LOCUS       DADXDL010000001       121806 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.001, whole genome shotgun sequence.
ACCESSION   DADXDL010000001 DADXDL010000000
VERSION     DADXDL010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 121806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 121806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..121806
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.001"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..668
                     /locus_tag="IRB70_000001"
     CDS             <1..668
                     /locus_tag="IRB70_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0629965.1"
                     /translation="VSSSKKYSDRAEWVLFLKVYSNAVLFIDIKHHDKNIEPNLFSQR
                     DLVETFIRNWPEAAEIFEMKGISGLACIHPTTDSDIANLRKNGINLPVVMDGKAYAPL
                     GMGITTARTAVSVSTYRNKIYHCAKHIEKIFMDEDSPYIKEIKSLGVNNPEFKMHMFN
                     DGGLGIVEINTRKGWKFLRKNADASHDVFSFLNNALMPEWASPVVLQFWEKTHCKMEG
                     IEN"
     gene            complement(843..1076)
                     /locus_tag="IRB70_000002"
     CDS             complement(843..1076)
                     /locus_tag="IRB70_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DinI family protein"
                     /protein_id="HBC0629966.1"
                     /translation="MRIEIMIDKEQKISQSILDALESELYRNLRPLYPKTVIRIRKGS
                     SNGVELTGLQLDEERKQVMKIMQKVWEDDSWLH"
     gene            complement(1087..1275)
                     /locus_tag="IRB70_000003"
     CDS             complement(1087..1275)
                     /locus_tag="IRB70_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0629967.1"
                     /translation="MQDYFLESLKLQRIDFFLKLVAASECSDEEKGLALQWVSELTDE
                     LMAKIRTHEYNRSMDVIS"
     gene            complement(1429..3843)
                     /locus_tag="IRB70_000004"
     CDS             complement(1429..3843)
                     /locus_tag="IRB70_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication endonuclease"
                     /protein_id="HBC0629968.1"
                     /translation="MSHADMNNCCGFNEAAASFSWNSPKKAINPYLDPAEVAPVSTLS
                     NLITLYAADNEQEQLRREALSDQVWERYFFNESRDPVQREMEQDKLISRAKLAHEQQR
                     FNPDMVILADVSAQPSHISKPLMQRIEYFSSLGRPKAYSRYLRETIKPCLERLEHVRD
                     SQLSASFRFMASHVGLDGLLILPEMSQDQVKRLSTLVAAHMSMCLDAACGDLYATDDV
                     KPEEIRKTWEKVAAETLRLDVIPPAFEQLRRKRNRRKPVPYELIPGSLARMLCADWWY
                     RKLWKMRCEWWEEQLRAVCLVSKKASPYVSYEAVMHKREQRRKSLEFFRSHELVNEEG
                     DTLDMEDVVNASSSNPAHRRNEMMACVKGLELIAEMRGDCAVFYTITCPSRFHSTLNN
                     GRPNPTWTNATVRQSSDYLVGMFAAFRKAMHKAGLRWYGVRVAEPHHDGTVHWHLLCF
                     MRKKDRRAITALLRKFAIREDREELGNNTGPRFKSELINPRKGTPTSYIAKYISKNID
                     GRGLAGEISKETGKSLRDNAEYVNAWASLHRVQQFRFFGIPGRQAYRELRLLAGQAAR
                     QQGDKKAGAPVLDNPRLDAILAAADAGCFATYIMKQGGVLVPRKYHLIRTAYEINEEP
                     TAYGDHGIRIYGIWSPIAEGKICTHAVKWKMVRKAVDVQEAAADQGACAPWTRGNNCP
                     LAENLNQQGKDKSADGDTRTDITRMNDKELHDYLHSMNKKERRELAARLRLVKPKRRR
                     DYKQRITDHQRQQLVYELKSRGFDGSEKEVDLLLRGGSIPSGAGLRIFYRNQRLQEDD
                     KWRNLY"
     gene            complement(3840..4697)
                     /locus_tag="IRB70_000005"
     CDS             complement(3840..4697)
                     /locus_tag="IRB70_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000104187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA adenine methylase"
                     /protein_id="HBC0629969.1"
                     /translation="MSTILKWAGNKTAIMSELKKHLPAGPRLVEPFAGSCAVMMETDY
                     PSYLVADINPDLINLYKKVAADCESFISRARVLFEIANREVAYYNIRQEFNYSTEITD
                     FMKAVYFLYLNRHGYRGLCRYNKSGHFNIPYGNYKNPYFPEKEIRAFAEKAQRATFIC
                     ASFDETLAMLKAGDVVYCDPPYDGTFSGYHTDGFTEDDQYHLASVLEHRSSEGHPVIV
                     SNSDTSLIRSLYRNFTHHYIKAKRSIGVAAGEGKSATEIIAVSGPRCWVGFDYSRGVD
                     SSAVYGVRA"
     gene            complement(4694..4921)
                     /locus_tag="IRB70_000006"
     CDS             complement(4694..4921)
                     /locus_tag="IRB70_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HBC0629970.1"
                     /translation="MADAMDLVQQRVEEERQRHIHAARAKTPGVSRVLCIECEAPIPP
                     ARRRAIPGVQLCITCQEIAELKGKHYNGGAV"
     gene            complement(4921..5154)
                     /locus_tag="IRB70_000007"
     CDS             complement(4921..5154)
                     /locus_tag="IRB70_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2732 family protein"
                     /protein_id="HBC0629971.1"
                     /translation="MRNIETLTTKTGPDDAGLNILLTEARLEERRARAEAMAARLDSL
                     ACHITSRQLNHVEAAELLRVTAEAIQNEAQEIH"
     gene            complement(5222..5563)
                     /locus_tag="IRB70_000008"
     CDS             complement(5222..5563)
                     /locus_tag="IRB70_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5347 domain-containing protein"
                     /protein_id="HBC0629972.1"
                     /translation="MAIEGAAATVPLSPGERLNGLNHIAELRAKVFGLNIESELERFI
                     KDMRDPRDINSEQNKRALAAIFFMAKIPAERHSISINELTTDEKRELIKAMNHFRAVV
                     SLFPRRLTMPN"
     gene            complement(5527..5727)
                     /locus_tag="IRB70_000009"
     CDS             complement(5527..5727)
                     /locus_tag="IRB70_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000956185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2724 domain-containing protein"
                     /protein_id="HBC0629973.1"
                     /translation="MLTKEPSFASLLVKQSPAMHYGHGWIMGEDGKRWHPCRSQDELL
                     AELSTKKRGNKWLLKALRRLFH"
     gene            complement(5735..6244)
                     /locus_tag="IRB70_000010"
     CDS             complement(5735..6244)
                     /locus_tag="IRB70_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory CII family protein"
                     /protein_id="HBC0629974.1"
                     /translation="MFDYQVSKHPHFDEACRAFALRHNLVQLAERAGMNVQILRNKLN
                     PAQPHLLTAPEIWLLTDLTEDSTLVDGFLAQIHCLPCVPINEVAKEKLPHYVMSATAE
                     IGRVAAGAVSGDVKTSAGRRDAISSINSVTRLMALAAVSLQARLQANPAMASAVDTVT
                     GFGASFGLL"
     gene            complement(6277..6498)
                     /locus_tag="IRB70_000011"
     CDS             complement(6277..6498)
                     /locus_tag="IRB70_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="regulator"
                     /protein_id="HBC0629975.1"
                     /translation="MTPNISITLNTPHVTIERYSELTGLSIDTINDMLADGRIPRHRL
                     RKDKKREKVMINLAALTVDALTDCNVVFN"
     gene            6594..7190
                     /locus_tag="IRB70_000012"
     CDS             6594..7190
                     /locus_tag="IRB70_000012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000107903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein CI"
                     /protein_id="HBC0629976.1"
                     /translation="MSTSKYPSEIKINPNKGGKAAIERLVEAYGFTTRQALADHLEVS
                     KSTLANRYLRDTFPADWIIQCALETGTSLKWLTTGQGLKQSSLTAATEELVKFRLAAG
                     KMIEDGSYVFDSSFLPANLSSPIVIQDGLVTYICDQKFSEVLDGNWLINIDGTYSIRK
                     ITRLPKGMIKITTAENSFECAFSDIEVVACIRSTIVSN"
     gene            7211..8887
                     /locus_tag="IRB70_000013"
     CDS             7211..8887
                     /locus_tag="IRB70_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBC0629977.1"
                     /translation="MNSFAIVIVLLAFLAPVLAVILFKQSKKHKAAIDNLTANNIALS
                     NQLIENQEKLAQTVRELSELEGRAAPLWQYEELHSAVMDAENKIKNADSIAKQKIDEA
                     QIKAAKTVNEANYQAQITISNANSEAIAITKDARDARLKAKERLDNANNKANELISNA
                     NDNAVKIISDAEERAKEIAGSAYEAKEFAEKYEAVAKSMKNKIEGYGDEWIIPNRSVL
                     DELAENYEFTDAGKELQKARELTKSLIKTNKAASCDYVEQNRRNTAINFVLDAFNGRV
                     DSILSKVKHNNFGKLSQEIKDAFQLVNYNGSAFRSAKISDIYLQARLNELKWGVAVNE
                     IMLEEKEEQRRIKEQLREEERARREYEKAIKEAEKEEKAIQQAINKATKELMLANEEQ
                     RLALEQKIAELQLKYEEAEAKNQRAISMAQQTRSGHVYIISNIGSFGEDVYKIGMTRR
                     LEPLDRVRELGDASVPFSFDVHAMIYSDDAPSLENHLHKVFNEKQVNKINSRKEFFNV
                     NLKEIKSVIEDMNINAHWTMFAEAKEYRESLAIEQERKAATSANDELHVA"
     gene            8970..10022
                     /locus_tag="IRB70_000014"
     CDS             8970..10022
                     /locus_tag="IRB70_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBC0629978.1"
                     /translation="MAVRKLTTGKWLCECYPAGRSGRRVRKQFATKGEALAFERYTMG
                     EIEAKPWLGESVDRRTLKDMVELWFKLHGKSLTAGQHVYNKLLLMVDALGNPLATDLT
                     SKMFAHYRDKRLTGEIYFSEKWKKGASPVTVNLEQSHLSSVFRELSRLGEWTLPNPLE
                     KMRKFTIAEKEMAWLTHEQIIELLSDCKRQNPILALVVKICLSTGARWREAINLTRSQ
                     VTKYRITFVRTKGKKNRSIPISKELYEEIMALDGFNFFTDCYFQFLSVMEKTSIVLPR
                     GQLTHVLRHTFAAHFMMSGGNILALQKILGHHDIKMTMRYAHLAPDHLETALRFNPLA
                     TLPNGDKVAAAVGITP"
     gene            complement(10127..10663)
                     /gene="rcdA"
                     /locus_tag="IRB70_000015"
     CDS             complement(10127..10663)
                     /gene="rcdA"
                     /locus_tag="IRB70_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RcdA"
                     /protein_id="HBC0629979.1"
                     /translation="MRRANDPQRREKIIQATLEAVKLYGIHAVTHRKIATLAGVPLGS
                     MTYYFSGIDELLLEAFSRFTEIMSRQYQAFFSDVSDAPGACQAITDMIYSSQVATPDN
                     MELMYQLYALASRKPLLKTVMQNWMQRSQQTLEQWFEPGTARALDAFIEGMTLHFVTD
                     RKPLSREEILRMVERVAG"
     gene            10747..11955
                     /locus_tag="IRB70_000016"
     CDS             10747..11955
                     /locus_tag="IRB70_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0629980.1"
                     /translation="MTVNSSRNALKRRTWALFMFFFLPGLLMASWATRTPAIRDILSV
                     SIAEMGGVLFGLSIGSMSGILCSAWLVKRFGTRNVILVTMSCALIGMMILSLALWLTS
                     PLLFAVGLGVFGASFGSAEVAINVEGAAVEREMNKTVLPMMHGFYSLGTLAGAGVGMA
                     LTAFGVPATVHILLAALVGIAPIYIAIQAIPDGTGKNAADGTQHGEKGVPFYRDIQLL
                     LIGVVVLAMAFAEGSANDWLPLLMVDGHGFSPTSGSLIYAGFTLGMTVGRFTGGWFID
                     RYSRVAVVRASALMGALGIGLIIFVDSAWVAGVSVVLWGLGASLGFPLTISAASDTGP
                     DAPTRVSVVATTGYLAFLVGPPLLGYLGEHYGLRSAMMVVLALVILAAIVAKAVAKPD
                     TKTQTAMENS"
     gene            11955..12770
                     /gene="ybjI"
                     /locus_tag="IRB70_000017"
     CDS             11955..12770
                     /gene="ybjI"
                     /locus_tag="IRB70_000017"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415365.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase"
                     /protein_id="HBC0629981.1"
                     /translation="MSIKLIAVDMDGTFLSDQKTYNRERFMAQYQQMKAQGIRFVVAS
                     GNQYYQLISFFPEIANEIAFVAENGGWVVSEGKDVFNGELSKDAFATVVEHLLTRPEV
                     EIIACGKNSAYTLKKYDDAMKTVAEMYYHRLEYVDNFDNLEDIFFKFGLNLSDELIPQ
                     VQKALHEAIGDIMVPVHTGNGSIDLIIPGVHKANGLRQLQKLWGIDDSEVVVFGDGGN
                     DIEMLRQAGFSFAMENAGSAVVAAAKYRAGSNNREGVLDVIDKVLKHEAPFNQ"
     gene            12856..13140
                     /locus_tag="IRB70_000018"
     CDS             12856..13140
                     /locus_tag="IRB70_000018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0629982.1"
                     /translation="MIMKNCLLLGALLMGFTGVAMAQSVTVDVPSGYKVVVVPDSVSV
                     PQAVSVATVPQTVYVAPAPAPAYRPHPYVRHLASVGEGMVIEHQIDDHHH"
     gene            complement(13181..14413)
                     /gene="mdfA"
                     /locus_tag="IRB70_000019"
     CDS             complement(13181..14413)
                     /gene="mdfA"
                     /locus_tag="IRB70_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdfA"
                     /protein_id="HBC0629983.1"
                     /translation="MQNKLASGARLGRQALLFPLCLVLYEFSTYIGNDMIQPGMLAVV
                     EQYQAGIDWVPTSMTAYLAGGMFLQWLLGPLSDRIGRRPVMLAGVVWFIVTCLAILLA
                     QNIEQFTLLRFLQGISLCFIGAVGYAAIQESFEEAVCIKITALMANVALIAPLLGPLV
                     GAAWIHVLPWEGMFVLFAALAAISFFGLQRAMPETATRIGEKLSLKELGRDYKLVLKN
                     GRFVAGALALGFVSLPLLAWIAQSPIIIITGEQLSSYEYGLLQVPIFGALIAGNLLLA
                     RLTSRRTVRSLIIMGGWPIMIGLLVAAAATVISSHAYLWMTAGLSIYAFGIGLANAGL
                     VRLTLFASDMSKGTVSAAMGMLQMLIFTVGIEISKHAWLNGGNGLFNLFNLVNGILWL
                     LLMVIFLKDKQMGNSHEG"
     gene            14698..15294
                     /gene="ybjG"
                     /locus_tag="IRB70_000020"
     CDS             14698..15294
                     /gene="ybjG"
                     /locus_tag="IRB70_000020"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBC0629984.1"
                     /translation="MLENLNLSLFSLINATPDSAPWMISLAIFIAKDLITVVPLLAAV
                     LWLWGLTAQRQLVIKIAIALAVSLLVSWTMGHLFPHDRPFVENIGYNFLHHAADDSFP
                     SDHGTVIFTFALAFLCWHRLWSGSLLMVLAVVIAWSRVYLGVHWPLDMLGGLLAGMIG
                     CLSAQIIWQAMGHKLYQRLQSWYRFCFALPIRKGWVRD"
     gene            15352..16110
                     /gene="deoR"
                     /locus_tag="IRB70_000021"
     CDS             15352..16110
                     /gene="deoR"
                     /locus_tag="IRB70_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor DeoR"
                     /protein_id="HBC0629985.1"
                     /translation="METRREERIGQLLQELKRSDKLHLKDAAALLGVSEMTIRRDLNN
                     HSAPVVLLGGYIVLEPRSASHYLLSDQKSRLVEEKRRAAKLAATLVEPDQTLFFDCGT
                     TTPWIIEAIDNEIPFTAVCYSLNTFLALKEKPHCRAFLCGGEFHASNAIFKPIDFQQT
                     LNNFCPDIAFYSAAGVHVSKGATCFNLEELPVKHWAMSMAQKHVLVVDHSKFGKVRPA
                     RMGDLKRFDIVVSDCCPEDEYVKYAQTQRIKLMY"
     gene            complement(16157..17359)
                     /gene="dacC"
                     /locus_tag="IRB70_000022"
     CDS             complement(16157..17359)
                     /gene="dacC"
                     /locus_tag="IRB70_000022"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HBC0629986.1"
                     /translation="MTQYSSLLRGLAAGSAFLFLFAPTAFAAEQTVEAPSVDARAWIL
                     MDYASGKVLAEGNADEKLDPASLTKIMTSYVVGQALKADKIKLTDMVTVGKDAWATGN
                     PALRGSSVMFLKPGDQVSVADLNKGVIIQSGNDACIALADYVAGSQESFIGLMNGYAK
                     KLGLTNTTFQTVHGLDAPGQFSTARDMALLGKALIHDVPEEYAIHKEKEFTFNKIRQP
                     NRNRLLWSSNLNVDGMKTGTTAGAGYNLVASATQGDMRLISVVLGAKTDRIRFNESEK
                     LLTWGFRFFETVTPIKPDATFVTQRVWFGDKSEVNLGAGEAGSVTIPRGQLKNLKASY
                     TLTEPQLTAPLKKGQVVGTIDFQLNGKSIEQRPLIVMENVEEGGFFGRMWDFVMMKFH
                     QWFGSWFS"
     gene            17606..18232
                     /gene="gstB"
                     /locus_tag="IRB70_000023"
     CDS             17606..18232
                     /gene="gstB"
                     /locus_tag="IRB70_000023"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308945.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase GstB"
                     /protein_id="HBC0629987.1"
                     /translation="MITLWGRNNSTNVKKVLLTLEELELPYEQILAGREFGINHDADF
                     LAMNPNGLVPLLRDDESDLILWESNAIVRYLAAQYGQKRLWIDSPARRAEAEKWMDWA
                     NQTLSNAHRGILMGLVRTPPEERDQAAIDASCKECDALFALLDAELAKVKWFSGDEFG
                     VGDIAIAPFIYNLFNVGLTWTPHPNLQRWYQQLTERPAVRKVVMIPVS"
     gene            complement(18229..19344)
                     /gene="yliI"
                     /locus_tag="IRB70_000024"
     CDS             complement(18229..19344)
                     /gene="yliI"
                     /locus_tag="IRB70_000024"
                     /EC_number="1.1.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose sugar dehydrogenase YliI"
                     /protein_id="HBC0629988.1"
                     /translation="MHRQFFFLVPLICLSSALWAAPATVNVEVLQDKLDHPWALAFLP
                     DNHGMLITLRGGELRHWQAGKGLSAPLSGVPDVWAHGQGGLLDVVLAPDFAQSRRIWL
                     SYSEVGDDGKAGTAVGYGRLSDDLSKVTDFRTVFRQMPKLSTGNHFGGRMVFDGKGYL
                     LIALGENNQRPTAQDLDKLQGKLVRLTDQGEIPDDNPFIKESGARAEIWSYGIRNPQG
                     MAMNPWSKALWLNEHGPRGGDEINIPQKGKNYGWPLATWGINYSGFKIPEAKGKIVAG
                     TEQPVFYWKDSPAVSGMAFYNSDKFPQWQQKLFIGALKDKDVIVMSVNGDKVTEDGRI
                     LTDRGQRIRDVRTGPDGYLYVLTDESSGELLKVSPRN"
     gene            complement(19455..19838)
                     /gene="bssR"
                     /locus_tag="IRB70_000025"
     CDS             complement(19455..19838)
                     /gene="bssR"
                     /locus_tag="IRB70_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssR"
                     /protein_id="HBC0629989.1"
                     /translation="MFVDRQRIDLLNRLIDARVDLAAYVQLRKAKGYMSVSESNHLRD
                     NFFKLNRELHDKSLRLNLHLDQEEWSALHHAEEALATAAVCLMSGHHDCPTVITVNAD
                     KLENCLMSLTLSIQSLQKHAMLEKA"
     gene            20051..21376
                     /gene="rimO"
                     /locus_tag="IRB70_000026"
     CDS             20051..21376
                     /gene="rimO"
                     /locus_tag="IRB70_000026"
                     /EC_number="2.8.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12 methylthiotransferase
                     RimO"
                     /protein_id="HBC0629990.1"
                     /translation="MSKVTPQPKIGFVSLGCPKNLVDSERILTELRTEGYDVVPSYDD
                     ADMVIVNTCGFIDSAVQESLEAIGEALNENGKVIVTGCLGAKEDQIREVHPKVLEITG
                     PHSYEQVLEHVHHYVPKPKHNPFLSLVPEQGVKLTPRHYAYLKISEGCNHRCTFCIIP
                     SMRGDLVSRPIGEVLSEAKRLVDAGVKEILVISQDTSAYGVDVKHRTGFHNGEPVKTS
                     MVSLCEQLSKLGIWTRLHYVYPYPHVDDVIPLMAEGKILPYLDIPLQHASPRILKLMK
                     RPGSVDRQLARIKQWREICPELTLRSTFIVGFPGETEEDFQMLLDFLKEARLDRVGCF
                     KYSPVEGADANALPDQVPEEVKEERWNRFMQLQQQISAERLQEKVGREILVIIDEVDE
                     EGAIGRSMADAPEIDGAVYLNGETNVKPGDILRVKVEHADEYDLWGSRV"
     gene            21602..21988
                     /locus_tag="IRB70_000027"
     CDS             21602..21988
                     /locus_tag="IRB70_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBC0629991.1"
                     /translation="MGVYKARRFSQSTKKLGIHDKVLMAAAEEVMQGIWEADLGSGVI
                     KKRLPLQQGKSGGARTIIFFKSANHVFFYDGWSKSGLSSKGTKEIEDDELAAYKKMAN
                     AFLAFSNKQIEDLIETGFLIEVKNER"
     gene            21978..22307
                     /locus_tag="IRB70_000028"
     CDS             21978..22307
                     /locus_tag="IRB70_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HBC0629992.1"
                     /translation="MSDKLQMMLEDAKELNALGLMSDSEVDAIAVMVKAREVSARIAK
                     VKSMTGEEIKAIRTRYGMSQSVLAHTMGMSKESVSKWERNEIKPSGPALRILNTLAIK
                     GPEVFAK"
     gene            complement(22377..23705)
                     /locus_tag="IRB70_000029"
     CDS             complement(22377..23705)
                     /locus_tag="IRB70_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBC0629993.1"
                     /translation="MSRINKFVLTVSLLIFIMISAVACGIYTQMVKERVYGLKQSVID
                     TAFAVANIAEYRRSVAIDLINTLNPTEEQLLVGLRTAYADSLSPSYLYDVGPYLISSD
                     ECIQVKEFEKNYCADIMQVVKYRHVKNTGFISFDGKTFVYYLYPVTHNRSLIFLLGLE
                     RFSLLSKSLAMDSENLMFSLFKNGKPVTGDEYNAKNAIFTVSEAMEHFSYLPTGLYVF
                     AYKKDVYFQVCTLIIFFAALVAVISGASCLYLVRRVINRGIVEKEAIINNHFERVLDG
                     GLFFSAADVKKLYSMYNSAFLDDLTKAMGRKSFDEDLKALPEKGGYLCLFDVDKFKNI
                     NDTFGHLLGDEVLMKVVKILKSQIPVDKGKVYRFGGDEFAVIYTGGTLEELLSILKEI
                     VHFQVGSINLSTSIGVAHSNECPTVERLKMLADERLYKSKKNGRAQISWQ"
     gene            complement(23713..26061)
                     /locus_tag="IRB70_000030"
     CDS             complement(23713..26061)
                     /locus_tag="IRB70_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBC0629994.1"
                     /translation="MLSLYEKIKIRLIILFLLAALSFIGLFFIINYQLVSERAVKRAD
                     SRFELIQKNVGYFFKDIERSALTLKDSLYLLKNTEEIQRAVILKMEMMPFLDSVGLVL
                     DDNKYYLFSRRANDKIVVYHQEQVNGPLVDESGRVIFADFNPSKRPWSVASDDSNNSW
                     NPAYNCFDRPGKKCISFTLHINGKDHDLLAVDKIHVDLNWRYLNEYLDQISANDEVLF
                     LKQGHEIIAKNQLAREKLIIYNSEGNYNIIDSVDTEYIEKTSAVPNNALFEIYFYYPG
                     GNLLNASDKLFYLPFAFIIIVLLVVYLMTTRVFRRQFSEMTELVNTLAFLPDSTDQIE
                     ALKIREGDAKEIISIKNSIAEMKDAEIERANKLLSLISYDQESGFIKNMAIIESNNNQ
                     YLAVGIIKLCGLEAVEAVFGVDERNKIVRKLCQRIAEKYAQCCDIVTFNADLYLLLCR
                     ENVQTFTRKIATVNDFDSSFGYRNLRIHKSAICEPLQGENAWSYAEKLKLAISSIRNH
                     MFSEFIFCDDAKLNEIEENIWIARNIRHAMEIGELFLVYQPIVDINTRAILGAEALCR
                     WVSAERGIISPLKFITIAEDIGFINELGYQIIKTAMGEFRHFSQRAVLKDGFLLHINV
                     SPWQLNEPHFHERFTTIMEENGLKANSLCVEITETVIERINEHFYLNIEQLRKQGVRI
                     SIDDFGTGLSNLKRFYEINPDSIKVDSQFTGDIFGTAGKIVRIIFDLARYNRIPVIAE
                     GVESEDVARELIKLGCVQAQGYLYQKPMPFSAWDKSGKLVKE"
     gene            complement(26238..27149)
                     /gene="gsiD"
                     /locus_tag="IRB70_000031"
     CDS             complement(26238..27149)
                     /gene="gsiD"
                     /locus_tag="IRB70_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiD"
                     /protein_id="HBC0629995.1"
                     /translation="MRLFNWRRQAVLNAMPLVKPDQVRTPWHEFWRRFRRQHMAMTAA
                     LFVILLIVVAIFARWIAPYDAENYFDYDNLNNGPSLQHWFGVDSLGRDIFSRVLVGAQ
                     ISLAAGVFAVFIGAAIGTLLGLLAGYYEGWWDRLIMRICDVLFAFPGILLAIAVVAVL
                     GSGIANVIIAVAIFSIPAFARLVRGNTLVLKQQTFIESARSIGASDMTILLRHILPGT
                     VSSIVVFFTMRIGTSIISAASLSFLGLGAQPPTPEWGAMLNEARADMVIAPHVAVFPA
                     LAIFLTVLAFNLLGDGLRDALDPKIKG"
     gene            complement(27152..28072)
                     /gene="gsiC"
                     /locus_tag="IRB70_000032"
     CDS             complement(27152..28072)
                     /gene="gsiC"
                     /locus_tag="IRB70_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter permease GsiC"
                     /protein_id="HBC0629996.1"
                     /translation="MLNYVIKRLLGLIPTLFIVSVLVFLFVHMLPGDPARLIAGPEAD
                     AQVIELVRQQLGLDQPLYHQFWHYISNAVQGDFGLAMVSRRPVGDEIASRFMPTLWLT
                     ITSMVWAVIFGMAAGIIAAVWRNRWPDRLSMTIAVSGISFPAFALGMLLIQVFSVELG
                     WLPTVGADSWQHYILPTLTLGAAVAAVMARFTRASFVDVLSEDYMRTARAKGVSETWV
                     VLKHGLRNAMIPVVTMMGLQFGFLLGGSIVVEKVFNWPGLGRLLVDSVEMRDYPVIQA
                     EILLFSLEFILINLVVDVLYAAINPAIRYK"
     gene            complement(28090..29628)
                     /gene="gsiB"
                     /locus_tag="IRB70_000033"
     CDS             complement(28090..29628)
                     /gene="gsiB"
                     /locus_tag="IRB70_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter substrate-binding
                     protein GsiB"
                     /protein_id="HBC0629997.1"
                     /translation="MARAVHRSGLVALGIATALMASCAFAAKDVVVAVGSNFTTLDPY
                     DANDTLSQAVAKSFYQGLFGLDKEMKLKNVLAESYTVSDDGLTYTVKLREGIKFQDGT
                     DFNAAAVKANLDRASDPANHLKRYNLYKNIAKTEAIDPTTVKITLKQPFSAFINILAH
                     PATAMISPAALEKYGKEIGFHPVGTGPYELDTWNQTDFVKVKKFAGYWQPGLPKLDSI
                     TWRPVADNNTRAAMLQTGEAQFAFPIPYEQAALLEKNKNIELMASPSIMQRYISMNVT
                     QKPFDNPKVREALNYAINRPALVKVAFAGYATPATGVVPPSIAYAQSYKPWPYDPAKA
                     RELLKEAGYPNGFSTTLWSSHNHSTAQKVLQFTQQQLAQVGIKAQVTAMDAGQRAAEV
                     EGKGQKESGVRMFYTGWSASTGEADWALSPLFASQNWPPTLFNTAFYSNKQVDDFLAQ
                     ALKTNDPAEKTRLYKAAQDIIWQESPWIPLVVEKLVSAHSKNLTGFWIMPDTGFSFED
                     ADLQ"
     gene            complement(29648..31519)
                     /gene="gsiA"
                     /locus_tag="IRB70_000034"
     CDS             complement(29648..31519)
                     /gene="gsiA"
                     /locus_tag="IRB70_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione ABC transporter ATP-binding protein
                     GsiA"
                     /protein_id="HBC0629998.1"
                     /translation="MPHSDELDAGDVLAVENLNIAFMQDQQKIAAVRNLSFSLQRGET
                     LAIVGESGSGKSVTALALMRLLEQAGGLVQCDKMLLRRRSREVIELSEQSAAQMRHVR
                     GADMAMIFQEPMTSLNPVFTVGEQIAESIRLHQNASREEAMVEAKRMLDQVRIPEAQT
                     ILSRYPHQLSGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEM
                     SMGVIFITHDMGVVAEIADRVLVMYQGEAVETGSVEQIFHAPQHPYTRALLAAVPQLG
                     AMKGLDYPRRFPLISLEHPAKQEPPIEQKTVVDGEPVLRVRNLVTRFPLRSGLLNRVT
                     REVHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLS
                     SGKLQALRRDIQFIFQDPYASLDPRQTIGDSIIEPLRVHGLLPGKEAAARVAWLLERV
                     GLLPEHAWRYPHEFSGGQRQRICIARALALNPKVIIADEAVSALDVSIRGQIINLLLD
                     LQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFENPQHPYTRKLLAA
                     VPVAEPSRQRPQRVLLSDDLPSNIHLRGEEVVAVSLQCVGPGHYVAQPQSEYAFMRR"
     gene            complement(31506..32471)
                     /gene="iaaA"
                     /locus_tag="IRB70_000035"
     CDS             complement(31506..32471)
                     /gene="iaaA"
                     /locus_tag="IRB70_000035"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBC0629999.1"
                     /translation="MGKAVIAIHGGAGAISRAQMSLQQELRYIEALSAIVETGQKMLE
                     AGESALNVVTEAVRLLEECPLFNAGIGAVFTRDETHELDACVMDGNTLKAGAVAGVSH
                     LRNPVLAARLVMEQSPHVMMIGEGAENFAFAHGMERVSPEIFSTPLRYEQLLAAREEG
                     ATVLDHSGAPLDEKQKMGTVGAVALDLDGNLAAATSTGGMTNKLPGRVGDSPLVGAGC
                     YANNASVAVSCTGTGEVFIRALAAYDIAALMDYGGLSLAEACERVVMEKLPALGGSGG
                     LIAIDHEGNVALPFNTEGMYRAWGYAGDTPTTGIYREKGDTVATQ"
     gene            32675..33910
                     /gene="moeA"
                     /locus_tag="IRB70_000036"
     CDS             32675..33910
                     /gene="moeA"
                     /locus_tag="IRB70_000036"
                     /EC_number="2.10.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin molybdotransferase MoeA"
                     /protein_id="HBC0630000.1"
                     /translation="MEFTTGLMSLDTALNEMLSRVTPLTAQETLPLVQCFGRILASDV
                     VSPLDVPGFDNSAMDGYAVRLADIASGQPLPVAGKSFAGQPYHGEWPAGTCIRIMTGA
                     PVPEGCEAVVMQEQTEQTDNGVRFTAEVRSGQNIRRRGEDISAGAVVFPAGTRLTTAE
                     LPVIASLGIAEVPVIRKVRVALFSTGDELQLPGQPLGDGQIYDTNRLAVHLMLEQLGC
                     EVINLGIIRDDPHALRAAFIEADSQADVVISSGGVSVGEADYTKTILEELGEIAFWKL
                     AIKPGKPFAFGKLSNSWFCGLPGNPVSATLTFYQLVQPLLAKLSGNTASGLPARQRVR
                     TASPLKKSPGRLDFQRGVLQRNADGELEVTTTGHQGSHIFSSFSLGNCFIVLERDRGN
                     VEVGEWVEVEPFNALFGGL"
     gene            33910..34659
                     /gene="moeB"
                     /locus_tag="IRB70_000037"
     CDS             33910..34659
                     /gene="moeB"
                     /locus_tag="IRB70_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-synthase adenylyltransferase MoeB"
                     /protein_id="HBC0630001.1"
                     /translation="MAELSDQEMLRYNRQIILRGFDFDGQEALKDSRVLIVGLGGLGC
                     AASQYLASAGVGNLTLLDFDTVSLSNLQRQTLHSDATVGQPKVKSARDALTRINPHIA
                     ITPVNALLDDAELAAMIAKHDLVLDCTDNVAVRNQLNAGCFAAKVPLVSGAAIRMEGQ
                     ITVFTYQDGEPCYRCLSRLFGENALTCVEAGVMAPLIGVIGSLQAMEAIKLLAGYGKP
                     ASGKIVMYDAMTCQFREMKLMRNPGCEVCGQ"
     gene            complement(34837..35499)
                     /gene="fsa"
                     /locus_tag="IRB70_000038"
     CDS             complement(34837..35499)
                     /gene="fsa"
                     /locus_tag="IRB70_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415346.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBC0630002.1"
                     /translation="MELYLDTSDVVAVKALSRIFPLAGVTTNPSIIAAGKKPLEVVLP
                     QLHEAMGGQGRLFAQVMATTAEGMVNDALKLRSIIADIVVKVPVTAEGLAAIKMLKAE
                     GIPTLGTAVYGAAQGLLSALAGAEYVAPYVNRIDAQGGSGIQTVTDLHQLLKMHAPQA
                     KVLAASFKTPRQALDCLLAGCESITLPLDVAQQMISYPAVDAAVAKFEQDWQGAFGRT
                     SI"
     gene            35630..36529
                     /locus_tag="IRB70_000039"
     CDS             35630..36529
                     /locus_tag="IRB70_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415345.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBC0630003.1"
                     /translation="MIFNIQRYSTHDGPGIRTVVFLKGCSLGCRWCQNPESRARTQDL
                     LYDPRLCLEGCELCAKAAPDVIERALNGLLIHREKLTPEHLTALTDCCPTQALTVCGE
                     VKSVEEIMATVLRDKPFYDRSGGGLTLSGGEPFMQPEMAMALLQASHEAGIHTAVETC
                     LHVPWKYIAPSLPYIDLFLADLKHVADAPFKQWTDGNAARVLDNLKKLASAGKKIIIR
                     VPLIQGFNADETSVKAITDFAADELHVGEIHFLPYHTLGINKYHLLNLPYDAPEKPLD
                     APELLDFAQQYACQKGLTATLRG"
     gene            36535..38967
                     /locus_tag="IRB70_000040"
     CDS             36535..38967
                     /locus_tag="IRB70_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBC0630004.1"
                     /translation="MTTLKLDTLSDRIKAHKNALVHIVKPPVCTERAQHYTEMYQQHL
                     DKPIPVRRALALAHHLANRTIWIKHDELIIGNQASEVRAAPIFPEYTVSWIEKEIDDL
                     ADRPGAGFAVSEENKRVLHEVCPWWRGQTVQDRCYGMFTDEQKGLLATGIIKAEGNMT
                     SGDAHLAVNFPLLLEKGLDGLREKVAERRSRINLTVLEDLHGEQFLKAIDIVLVAVSE
                     HIERFAALAREMATTETRESRRDELLAMAENCDLIAHQPPQTFWQALQLCYFIQLILQ
                     IESNGHSVSFGRMDQYLYPYYRRDVELNQTLDREHAIEMLHSCWLKLLEVNKIRSGSH
                     SKASAGSPLYQNVTIGGQNLVDGQPMDAVNPLSYAILESCGRLRSTQPNLSVRYHAGM
                     SNDFLDACVQVIRCGFGMPAFNNDEIVIPEFIKLGIEPQDAYDYAAIGCIETAVGGKW
                     GYRCTGMSFINFARVMLAALEGGRDATSGKVFLPQEKALSAGNFNNFDEVMDAWDTQI
                     RYYTRKSIEIEYVVDTMLEENVHDILCSALVDDCIERAKSIKQGGAKYDWVSGLQVGI
                     ANLGNSLAAVKKLVFEQGAIGQQQLAAALADDFDGLTHEQLRQRLINGAPKYGNDDDT
                     VDTLLARAYQTYIDELKQYHNPRYGRGPVGGNYYAGTSSISANVPFGAQTMATPDGRK
                     AHTPLAEGASPASGTDHLGPTAVIGSVGKLPTAAILGGVLLNQKLNPATLENESDKQK
                     LMILLRTFFEVHKGWHIQYNIVSRETLLEAKKHPDQYRDLVVRVAGYSAFFTALSPDA
                     QDDIIARTEHML"
     gene            39113..39928
                     /gene="ybiV"
                     /locus_tag="IRB70_000041"
     CDS             39113..39928
                     /gene="ybiV"
                     /locus_tag="IRB70_000041"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase YbiV"
                     /protein_id="HBC0630005.1"
                     /translation="MSVKVIVTDMDGTFLNDAKTYNQPRFMAQYQELKKRGIEFVVAS
                     GNQYYQLISFFPELKDEISFVAENGALVYEHGKQLFHGELTRHESRIVIGELLKDKQL
                     NFVACGLQSAYVSENAPEAFVALMAKHYHRLKPVKDYQEIDDVLFKFSLNLPDEQIPL
                     VIDKLHIALDGIMKPVTSGFGFIDLIIPGLHKANGISRLLKRWDLSPQNVVAIGDSGN
                     DAEMLKMARYSFAMGNAAENIKQIARYATDDNNHEGALNVIQAVLDNRSPFNS"
     gene            40080..41345
                     /locus_tag="IRB70_000042"
     CDS             40080..41345
                     /locus_tag="IRB70_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003570920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1479 domain-containing protein"
                     /protein_id="HBC0630006.1"
                     /translation="MASTFTSNTLPADHKAAIRQMKHALRAQLGDVQQIFNQLSDDIA
                     TRVAEINALKAQGDAVWPVLSYADIKAGHVTAEQREQIKRRGCAVIKGHFPREQALGW
                     DQSMLDYLDRNRFDEVYKGPGDNFFGTLSASRPEIYPIYWSQAQMQARQSEEMANAQS
                     FLNRLWTFESDGKQWFNPDVSVIYPDRIRRRPPGTASKGLGAHTDSGALERWLLPAYQ
                     RVFANVFNGNLAQYDPWHAAHRTEVEEYTVDNTTKCSVFRTFQGWTALSDMLPGQGLL
                     HVVPIPEAMAYVLLRPLLDDVPEDELCGVAPGRVLPVSEQWHPLLIEALTSIPQLEAG
                     DSVWWHCDVIHSVAPVENQQGWGNVMYIPAAPMCEKNLAYAHKVKAALEKGASPGDFP
                     REDYETNWEGRFTLADLNIHGKRALGIDS"
     gene            complement(41312..42415)
                     /locus_tag="IRB70_000043"
                     /pseudo
     CDS             complement(41312..42415)
                     /locus_tag="IRB70_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001589948.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
     gene            42708..44009
                     /locus_tag="IRB70_000044"
     CDS             42708..44009
                     /locus_tag="IRB70_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000077530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630007.1"
                     /translation="MSQGINNDMTASKPRHIVKNLRWWMLVLFLLGVTVNYITRNSLG
                     ILAPELKSSLGITTEQYSWIVGAFQLAYTLFQPLCGWLIDVIGLKLGFMICAGLWALA
                     CLMHAGAGNWVHLALLRFFMGGAEAAATPANAKTIGEWFPKSERPIAAGWAGVGFSIG
                     AMLAPPIIYFAHASFGWQGAFMFTGILAMLWVVLWWAFYHNPDKHPNLSKAELDFIRQ
                     DNEAPPVKLPFLTALKTVGKNKRFYGIAIPAFMAEPAWAVMSFWVPLYLSKSYGMDLK
                     QIALFAWLPFLAADLGSIASGYLTKLYTRLFGLSRVNSVVASSVSGAFLMVSLAVMAF
                     INNPYIAIVLISIGGFGHQIISCMLSALVVESFDKGQMATVNGMRGSAAWIASFLFSL
                     IIGVTADKIGFNPLFIAMGFFDLIGAFFLVTFIAERRAKRA"
     gene            44024..46387
                     /locus_tag="IRB70_000045"
     CDS             44024..46387
                     /locus_tag="IRB70_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 31 protein"
                     /protein_id="HBC0630008.1"
                     /translation="MKTLKNWTLHKQSAHHVELLVDGQHILCLYVLEENLFRVLLKRK
                     GELALDRTWSIAPAQDVPWEGRSREDLSGFSLPAWTLNQHDNTVVIATESLRATVHQP
                     LWLEWHYRNNEGEWLPLVNDRPTSAYLLNAHGDGVAHYQSRRKDERFYGLGDKAGDLQ
                     RNGKRYEMRNLDAMGYNAVSTDPLYKHIPFTITRRDDVSFGLFYDNLSSCWLDLGNEI
                     DNYHTAYRRWRAEAGDIDYYLFTGERVLDITKAFVRLTGKTLFGPKWSLGYSGSTMHY
                     TDAPDAQNQLMNFIRLCEEHAIPCDSFQLSSGYTSINGKRYVFNWNYDKVPQPKVMSQ
                     AFHDAGMHLAANIKPCLLQDHPRYNEVAERGLFIRDSETDEPERSSFWDDEGSNLDFT
                     NPQTIQWWQEGVTTQLLEMGIDSTWNDNNEFEVWDGEARCHGFGQTIAIKHIRPVMPL
                     LMMRASMEAQQRFAPEKRPYLISRSGCAGMQRYVQTWSGDNRTSWDTLRYNTRMGLGM
                     SLSGLYNLGHDVGGFSGDKPDPELFVRWVQNGVMHPRFTIHSWNDDHTVNEPWMYPGV
                     TPAIRSAIELRYRLLPYFYTLMWQAYADDEPMLRPTFLDHEHDVQTFEECDDFLLGRD
                     ILVASVVEQGERQRRVWLPDNETGWYDFYNGEWFSGGQWITLDAPLEKLPLMVRAGAG
                     LPLSKRITYVSAEQDDTRELKLFPLKGVGTTSGLLFEDDGESWGYQTGNALWVEWEMV
                     CDGATINLKVNARGDYRPAWSVLKVSLPVEEKRTLLVNGVEGSEWIR"
     gene            complement(46567..48162)
                     /locus_tag="IRB70_000046"
     CDS             complement(46567..48162)
                     /locus_tag="IRB70_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001522676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATPase"
                     /protein_id="HBC0630009.1"
                     /translation="MLVSSNVTMQFGSKPLFENISVKFGGGNRYGLIGANGSGKSTFM
                     KILGGDLEPTLGNVSLDPNERIGKLRQDQFAFEEFTVLDTVIMGHKELWEVKQERDRI
                     YALPEMSEEDGYKVADLEVKYGEMDGYSAEARAGELLLGVGIPVEQHYGPMSEVAPGW
                     KLRVLLAQALFADPDILLLDEPTNNLDIDTIRWLEQVLNERDSTMIIISHDRHFLNMV
                     CTHMADLDYGELRVYPGNYDEYMTAATQARERLLADNAKKKAQIAELQSFVSRFSANA
                     SKSRQATSRARQIDKIKLEEVKASSRQNPFIRFEQDKKLFRNALEVEGLTKGFDNGPL
                     FKNLNLLLEVGEKLAVLGTNGVGKSTLLKTLVGDLQPDSGTVKWSENARIGYYAQDHE
                     YEFENDLTVFEWMSQWKQEGDDEQAVRSILGRLLFSQDDIKKPAKVLSGGEKGRMLFG
                     KLMMQKPNILIMDEPTNHLDMESIESLNMALELYQGTLIFVSHDREFVSSLATRILEI
                     TPERVIDFSGNYEDYLRSKGIDG"
     gene            48381..49301
                     /gene="ldtB"
                     /locus_tag="IRB70_000047"
     CDS             48381..49301
                     /gene="ldtB"
                     /locus_tag="IRB70_000047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HBC0630010.1"
                     /translation="MNMKLKTLFAAAFAVVGFCSTASAVTYPLPTDGSRLVGQNQVIT
                     IPEGNTQPLEYFAAEYQMGLSNMMEANPGVDTFLPKGGTVLNIPQQLILPDTVHEGIV
                     INSAEMRLYYYPKGSNTVIVLPIGIGQLGKDTPINWTTKVERKKAGPTWTPTAKMHAE
                     YRAAGEPLPAVVPAGPDNPMGLYALYIGRLYAIHGTNANFGIGLRVSHGCVRLRNEDI
                     KFLFEKVPVGTRVQFIDEPVKATTEPDGSRYIEVHNPLSTTEAQFEGQEIVPITLTKS
                     VQTVTGQPDVDQVVLDEAIKNRSGMPVRLN"
     gene            complement(49360..50478)
                     /locus_tag="IRB70_000048"
     CDS             complement(49360..50478)
                     /locus_tag="IRB70_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion transporter"
                     /protein_id="HBC0630011.1"
                     /translation="MSLPFLSTLQGDRFFQLLILVGIGLSFFVPFAPKSWPAAIDWHT
                     IITLSGLMLLTKGVELSGYFDVLGRKMVRRFATERRLAMFMVLAAALLSTFLTNDVAL
                     FIVVPLTITLKRLCEIPVNRLIIFEALAVNAGSLLTPIGNPQNILIWGRSGLSFAGFI
                     AQMAPLAGAMMLTLLLLCWCCFPGKALQYHTGAQTPEWKPRLVWSCLGLYIVFLTALE
                     FKQELWGLVIVAAGFALLARCVVLSVDWTLLLVFMAMFIDVHLLTQLPALQGVLGNVS
                     HLSEPGLWLTAIGLSQVISNVPSTILLLNYVPPSLLLAWAVNVGGFGLLPGSLANLIA
                     LRMANDRRIWWRFHLYSIPMLLWAALVGYVLFVMLPAN"
     gene            complement(50475..50942)
                     /gene="mntR"
                     /locus_tag="IRB70_000049"
     CDS             complement(50475..50942)
                     /gene="mntR"
                     /locus_tag="IRB70_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-binding transcriptional regulator
                     MntR"
                     /protein_id="HBC0630012.1"
                     /translation="MSRRAGTPTAKKVTQLVNVEEHVEGFRQVREAHRRELIDDYVEL
                     ISDLIREVGEARQVDMAARLGVSQPTVAKMLKRLATMGLIEMIPWRGVFLTAEGEKLA
                     QESRERHQIVENFLLVLGVSPEIARRDAEGMEHHVSEETLDAFRLFTQKHGAK"
     gene            51128..51256
                     /gene="mntS"
                     /locus_tag="IRB70_000050"
     CDS             51128..51256
                     /gene="mntS"
                     /locus_tag="IRB70_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganase accumulation protein MntS"
                     /protein_id="HBC0630013.1"
                     /translation="MNEFKRCMRVFSHSPFKVRLMLLSMLCDMVNNKPQQDKPSDK"
     gene            51528..53111
                     /gene="opgE"
                     /locus_tag="IRB70_000051"
     CDS             51528..53111
                     /gene="opgE"
                     /locus_tag="IRB70_000051"
                     /EC_number="2.7.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HBC0630014.1"
                     /translation="MNLTLKESLVTRSRVFSPWTAFYFLQSLLINLGLGYPFSLLYTA
                     AFTAILLLLWRTLPRVQKVLVGVSSLVAACYFPFAQAYGAPNFNTLLALHSTNMEEST
                     EILTIFPWYSYLVGLFIFALGVIAIRRKKENEKARWNTFDSLCLVFSVATFFVAPVQN
                     LAWGGVFKLKDTGYPVFRFAKDVIVNNNEVIEEQERMAKLSGMKDTWTVTAVKPKYQT
                     YVVVIGESARRDALGAFGGHWDNTPFASSVNGLIFADYIAASGSTQKSLGLTLNRVVD
                     GKPQFQDNFVTLANRAGFQTWWFSNQGQIGEYDTAIASIAKRADEVYFLKEGNFEADK
                     NTKDEALLDMTAQVLAQEHSQPQLIVLHLMGSHPQACDRTQGKYETFVQSKETSCYLY
                     TMTQTDDLLRKLYDQLRNSGSSFSLVYFSDHGLAFKERGKDVQYLAHDDKYQQNFQVP
                     FMVISSDDKAHRVIKARRSANDFLGFFSQWTGIKAKEINIKYPFISEKKAGPIYITNF
                     QLQKVDYNHLGTDIFDPKP"
     gene            complement(53160..53675)
                     /gene="ompX"
                     /locus_tag="IRB70_000052"
     CDS             complement(53160..53675)
                     /gene="ompX"
                     /locus_tag="IRB70_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpX"
                     /protein_id="HBC0630015.1"
                     /translation="MKKIACLSALAAVLAFTAGTSVAATSTVTGGYAQSDAQGQMNKM
                     GGFNLKYRYEEDNSPLGVIGSFTYTEKSRTASSGDYNKNQYYGITAGPAYRINDWASI
                     YGVVGVGYGKFQTTEYPTYKHDTSDYGFSYGAGLQFNPMENVALDFSYEQSRIRSVDV
                     GTWIAGVGYRF"
     gene            complement(53728..53793)
                     /locus_tag="IRB70_000053"
     CDS             complement(53728..53793)
                     /locus_tag="IRB70_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630016.1"
                     /translation="METFCYMKWPVRHHKSRRVSH"
     gene            54028..54915
                     /gene="rhtA"
                     /locus_tag="IRB70_000054"
     CDS             54028..54915
                     /gene="rhtA"
                     /locus_tag="IRB70_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/homoserine exporter RhtA"
                     /protein_id="HBC0630017.1"
                     /translation="MPGSLRKMPVWLPIVILLVAMASIQSGASLAKSLFPLVGAPGVT
                     ALRLALGTLILIAFFKPWRLRFAKEQRLPLLFYGVSLGGMNYLFYLSIQTVPLGIAVA
                     LEFTGPLAVALFSSRRPVDFVWVVLAVLGLWFLLPLGQDVSHVDLTGCALALGAGACW
                     AIYILSGQRAGAEHGPATVAIGSLIAALIFVPIGALQAGEALWHWSVIPLGLAVAILS
                     TALPYSLEMIALTRLPTRTFGTLMSMEPALAAVSGMIFLGETLTPIQLLALGAIIAAS
                     MGSTLTVRKESKIKELDIN"
     gene            55215..55718
                     /gene="dps"
                     /locus_tag="IRB70_000055"
                     /gene_synonym="pexB"
     CDS             55215..55718
                     /gene="dps"
                     /locus_tag="IRB70_000055"
                     /gene_synonym="pexB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001730644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein Dps"
                     /protein_id="HBC0630018.1"
                     /translation="MSTAKLVKSKATNLLYTRNDVSDSEKKATVELLNRQVIQFIDLS
                     LITKQAHWNMRGANFIAVHEMLDGFRTALIDHLDTMAERAVQLGGVALGTTQVINSKT
                     PLKSYPLDIHNVQDHLKELADRYAIVANDVRKAIGEAKDDDTADILTAASRDLDKFLW
                     FIESNIE"
     gene            56122..56868
                     /gene="glnH"
                     /locus_tag="IRB70_000056"
     CDS             56122..56868
                     /gene="glnH"
                     /locus_tag="IRB70_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter substrate-binding
                     protein GlnH"
                     /protein_id="HBC0630019.1"
                     /translation="MKSVLKVSLAALTLAFAVSSHAADKKLVVATDTAFVPFEFKQGD
                     KYVGFDVDLWAAIAKELKLDYELKPMDFSGIIPALQTKNVDLALAGITITDERKKAID
                     FSDGYYKSGLLVMVKANNNDVKSVKDLDGKVVAVKSGTGSVDYAKANIKTKDLRQFPN
                     IDNAYMELGTNRADAVLHDTPNILYFIKTAGNGQFKAVGDSLEAQQYGIAFPKGSDEL
                     RDKVNGALKTLRENGTYNEIYKKWFGTEPK"
     gene            57007..57666
                     /gene="glnP"
                     /locus_tag="IRB70_000057"
     CDS             57007..57666
                     /gene="glnP"
                     /locus_tag="IRB70_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015367581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter permease GlnP"
                     /protein_id="HBC0630020.1"
                     /translation="MQFDWSAIWPAIPLLIEGAKMTLWISVLGLAGGLVIGLLAGFAR
                     TFGGWIANHVALVFIEVIRGTPIVVQVMFIYFALPMAFNDLRIDPFTAAVVTIMINSG
                     AYIAEITRGAVLSIHKGFREAGLALGLSRWETIRYVILPLALRRMLPPLGNQWIISIK
                     DTSLFIVIGVAELTRQGQEIIAGNFRALEIWSAVAVFYLIITLVLSFILRRLERRMKI
                     L"
     gene            57663..58385
                     /gene="glnQ"
                     /locus_tag="IRB70_000058"
     CDS             57663..58385
                     /gene="glnQ"
                     /locus_tag="IRB70_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000569103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine ABC transporter ATP-binding protein
                     GlnQ"
                     /protein_id="HBC0630021.1"
                     /translation="MIEFKNVSKHFGPTQVLHNIDLNIAQGEVVVIIGPSGSGKSTLL
                     RCINKLEEITSGDLIVDGLKVNDPKVDERLIRQEAGMVFQQFYLFPHLTALENVMFGP
                     LRVRGANKEEAEKLARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKPKMMLF
                     DEPTSALDPELRHEVLKVMQDLAEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDG
                     DPQVLIKNPPSQRLQEFLQHVS"
     gene            58501..60726
                     /gene="ybiO"
                     /locus_tag="IRB70_000059"
     CDS             58501..60726
                     /gene="ybiO"
                     /locus_tag="IRB70_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel protein"
                     /protein_id="HBC0630022.1"
                     /translation="MRWILFILFCLLGAPAHAVSIPGVTTTTTTDSTTEPAPEPDIEQ
                     KKAAYGALADVLDNDTSRKELIDQLRTVAATPPAEPVPKIVPPTLVEEQTVLQKVTEV
                     SRHYGEALSARFGQLYRNITGSPHKPFNPQTFSNALTHFSMLAVLVFGFYWLIRLCAL
                     PLYRKMGQWARQKNRERSNWLQLPAMIIGAFIIDLLLLALTLFVGQVLSDNLNAGSRT
                     IAFQQSLFLNAFALIEFFKAVLRLIFCPNVAELRPFTIHDETARYWSRRLSWLSSLIG
                     YGLIVAVPIISNQVNVQIGALANVIIMLCMTVWALYLIFRNKKEITQHLLNFAEHSLA
                     FFSLFIRAFALVWHWLASAYFIVLFFFSLFDPGNSLKFMMGATVRSLAIIGIAAFVSG
                     MFSRWLAKTITLSPHTQRNYPELQKRLNGWLSAALKTARILTVCVAVMLLLSAWGLFD
                     FWNWLQNGAGQKTVDILIRIALILFFSAVGWTVLASLIENRLASDIHGRPLPSARTRT
                     LLTLFRNALAVIISTITIMIVLSEIGVNIAPLLAGAGALGLAISFGSQTLVKDIITGV
                     FIQFENGMNTGDLVTIGPLTGTVERMSIRSVGVRQDTGAYHIIPWSSITTFANFVRGI
                     GSVVANYDVDRHEDADKANQALKDAVAELMENEEIRGLIIGEPNFAGIVGLSNTAFTL
                     RVSFTTLPLKQWTVRFALDSQVKKHFDLAGVRAPVQTYQVLPAPGATPAEPLPPGEPT
                     L"
     gene            complement(60723..61649)
                     /gene="rlmF"
                     /locus_tag="IRB70_000060"
     CDS             complement(60723..61649)
                     /gene="rlmF"
                     /locus_tag="IRB70_000060"
                     /EC_number="2.1.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415328.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(1618)-N(6))-methyltransferase
                     RlmF"
                     /protein_id="HBC0630023.1"
                     /translation="MSAQKPGLHPRNRHHSRYDLATLCQVNPELRQFLTLTPAGEQSV
                     DFANPLAVKALNKALLAHFYAVANWDIPDGFLCPPVPGRADYIHHLADLLAEATGSIP
                     ANASILDIGVGANCIYPLIGVHEYGWRFTGSETSSQALSSAQAIISANPGLNRAIRLR
                     RQKESGAIFNGIIHKNEQYDATLCNPPFHDSAAAARAGSERKRRNLGLNKDDALNFGG
                     QQQELWCEGGEVAFIKKMIEESKGFAKQVMWFTSLVSRGENLPPLYRALTDVGAVKVV
                     KKEMAQGQKQSRFIAWTFMNDEQRRRFVNRQR"
     gene            61925..62185
                     /locus_tag="IRB70_000061"
     CDS             61925..62185
                     /locus_tag="IRB70_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415327.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBC0630024.1"
                     /translation="MKKCLTLLIATVLSGISLTAYAAQPMSNLDSGQLRPAGTVSATG
                     ASNLSDLEDKLAEKAREQGAKGYVINSAGGNDQMFGTAIIYK"
     gene            62450..64732
                     /locus_tag="IRB70_000062"
     CDS             62450..64732
                     /locus_tag="IRB70_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor Fiu"
                     /protein_id="HBC0630025.1"
                     /translation="MENNRNFPARQFHSLTFFAGLCIGITPVAQALAAEGQTNADDTL
                     VVEASTPSLYAPQQSADPKFSRPVADTTRTMTVISEQVIKDQGATNLTDALKNVPGVG
                     AFFAGENGNSTTGDAIYMRGADTSNSIYIDGIRDIGSVSRDTFNTEQVEVIKGPSGTD
                     YGRSAPTGSINMISKQPRNDSGIDASASIGSAWFRRGTLDVNQVIGDTTAVRLNVMGE
                     KTHDAGRDKVKNERYGVAPSVAFGLGTANRLYLNYLHVTQHNTPDGGIPTIGLPGYSA
                     PSAGTAALNHSGKVDTHNFYGTDSDYDDSTTDTATMRFEHDINDNTTIRNTTRWSRVK
                     QDYLMTAIMGGASNITQPTSDVNSWTWSRTANTKDVSNKILTNQTNLTSTFYTGSIGH
                     DVSTGVEFTRETQTNYGVNPVTLPAVNIYHPDSSIHPGGLTRNGANANGQTDTFAIYA
                     FDTLQITRDFELNGGIRLDNYHTEYDSATACGGSGRGAITCPAGVAKGSPVTTVDTAK
                     SGNLVNWKAGALYHLTENGNVYINYAVSQQPPGGNNFALAQSGSGNSANRTDFKPQKA
                     NTSEIGTKWQVLDKRLLLTAALFRTDIENEVEQNDDGTYSQYGKKRVEGYEISVAGNI
                     TPAWQVIGGYTQQKATIKNGKDVAQDGSSSLPYTPEHAFTLWSQYQATDDISVGAGAR
                     YIGSMHKGSDGAVGTPAFTEGYWVADAKLGYRVNRNLDFQLNVYNLFDTDYVASINKS
                     GYRYHPGEPRTFLLTANMHF"
     gene            64774..65451
                     /gene="ybiX"
                     /locus_tag="IRB70_000063"
     CDS             64774..65451
                     /gene="ybiX"
                     /locus_tag="IRB70_000063"
                     /EC_number="1.14.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PKHD-type hydroxylase YbiX"
                     /protein_id="HBC0630026.1"
                     /translation="MMYHIPGVLSPKDVARFREQLEQAEWVDGRVTTGAQGAQVKNNQ
                     QVDTRSTLYAALQNEVLNAVNQHALFFAAALPRTLSTPLFNRYQNNETYGFHVDGAVR
                     SHPQNGWMRTDLSATLFLSDPESYDGGELVVNDTFGQHRVKLPAGDLVLYPSSSLHCV
                     TPVTRGVRVASFMWIQSMIRDDKKRAMLFELDTNIQSLKSRHGESEEILSLLNLYHNL
                     LREWSEI"
     gene            65525..65791
                     /gene="ybiI"
                     /locus_tag="IRB70_000064"
     CDS             65525..65791
                     /gene="ybiI"
                     /locus_tag="IRB70_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-type zinc finger protein YbiI"
                     /protein_id="HBC0630027.1"
                     /translation="MASGWANDDAVNEQINSTIEDAIARARGEIPHGESLYECEECGA
                     PIPQARREAIPGVRLCIHCQQEKDLQKPAYTGYNRRGSKDSQLR"
     gene            66056..66316
                     /locus_tag="IRB70_000065"
     CDS             66056..66316
                     /locus_tag="IRB70_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBC0630028.1"
                     /translation="MKTINTVVAAMALSTLSFGVFAAEPVTASQAQNMNKIGVVSADG
                     ASTLDALEAKLAEKAAAAGASGYSITSATNNNKLSGTAVIYK"
     gene            complement(66456..67541)
                     /gene="hcxB"
                     /locus_tag="IRB70_000066"
     CDS             complement(66456..67541)
                     /gene="hcxB"
                     /locus_tag="IRB70_000066"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcXB"
                     /protein_id="HBC0630029.1"
                     /translation="MESGHRFDAQTLHSFIQAVFRQMGSEEQEAKLVADHLIAANLAG
                     HDSHGIGMIPSYVRSWSQGHLQINHHAKIVKEAGAAVTLDGDRAFGQVAAHEAMALGI
                     EKAHQHGIAAVALHNSHHIGRIGYWAEQCAAAGFVSIHFVSVVGIPMVAPFHGRDSRF
                     GTNPFCVVFPRRDNFPLLLDYATSAIAFGKTRVAWHKGVPVPPGCLIDVNGVPTTNPA
                     VMQESPLGSLLTFAEHKGYALAAMCEILGGALSGGKTTHQETLQTSPDAILNCMTTII
                     INPELFGAPDCSAQTEAFAEWVKASPHDDDKPILLPGEWEVNTRRERQEQGIPLDAGS
                     WQAICDAARQIGMPEETLQAFCQQLAS"
     gene            complement(67682..68644)
                     /gene="ybiB"
                     /locus_tag="IRB70_000067"
     CDS             complement(67682..68644)
                     /gene="ybiB"
                     /locus_tag="IRB70_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein YbiB"
                     /protein_id="HBC0630030.1"
                     /translation="MDYRKIIKEIGRGKNHARDLDRDTARGLYAHMLNGEVPDLELGG
                     VLIALRIKGEGEAEMLGFYEAMQNHTIKLTPPADKPMPIVIPSYNGARKQANLTPLLA
                     ILLHKLGFPVVVHGVSEDPTRVLTETIFELMGITPTLHGGQAQAKLDEHQPVFMPVGA
                     FCPPLEKQLAMRWRMGVRNSAHTLAKLATPFAEGEALRLSSVSHPEYIGRVAKFFSDI
                     GGRALLMHGTEGEVYANPQRCPQINLIDREGMRVLYEKQDTAGSELLPQAKDPETTAQ
                     WIERCLAGSEPIPESLKIQMACCLVATGEAATISDGLARVNQAF"
     gene            complement(68672..70822)
                     /gene="dinG"
                     /locus_tag="IRB70_000068"
     CDS             complement(68672..70822)
                     /gene="dinG"
                     /locus_tag="IRB70_000068"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase DinG"
                     /protein_id="HBC0630031.1"
                     /translation="MALTAALKAQIAAWYKALQEQIPDFIPRAPQRQMIADVAKTLAG
                     EEGRHLAIEAPTGVGKTLSYLIPGIAIAREEQKTLVVSTANVALQDQIYSKDLPLLKK
                     IIPDLKFTAAFGRGRYVCPRNLTALASTEPTQQDLLAFLDDELTPNNQEEQKRCAKLK
                     GDLDTYKWDGLRDHTDIAIDDDLWRRLSTDKASCLNRNCYYYRECPFFVARREIQEAE
                     VVVANHALVMAAMESEAVLPDPKNLLLVLDEGHHLPDVARDALEMSAEITAPWYRLQL
                     DLFTKLVATCMEQFRPKTIPPLAIPERLNAHCEELYELIASLNNILNLYMPAGQEAEH
                     RFAMGELPDEVQEICQRLAKLTEMLRGLAELFLNDLSEKTGSHDIVRLHRLILQMNRA
                     LGMFEAQSKLWRLASLAQSSGAPVTKWATREEREGQLHLWFHCVGIRVSDQLERLLWR
                     SIPHIIVTSATLRSLNSFSRLQEMSGLKEKAGDRFVALDSPFNHCEQGKIVIPRMRVE
                     PSLDNEEQHIAEMAAFFRKQVESKKHLGMLVLFASGRAMQRFLDYVTDLRLMLLVQGD
                     QPRYRLVELHRKRVANGERSVLVGLQSFAEGLDLKGDLLSQVHIHKIAFPPIDSPVVI
                     TEGEWLKSLNRYPFEVQSLPSASFNLIQQVGRLIRSHGCWGEVVIYDKRLLTKNYGKR
                     LLDALPVFPIEQPEVPEGIVKKKEKTKSPRRRRR"
     gene            70942..71424
                     /gene="ybiA"
                     /locus_tag="IRB70_000069"
     CDS             70942..71424
                     /gene="ybiA"
                     /locus_tag="IRB70_000069"
                     /EC_number="3.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-glycosidase YbiA"
                     /protein_id="HBC0630032.1"
                     /translation="MPVRAQRIQHVMQDTIINFYSTGDDYGDFSNFAAWPIKVDGKTW
                     PTSEHYFQAQKFLDEKYREEIRRVSSPMVAARMGRDRSKPLRKNWESVKEQVMRKALR
                     AKFEQHAELRALLLATAPAKLVEHTENDAYWGDGGNGKGKNRLGYLLMELREQLAIEK
                     "
     gene            complement(71658..73019)
                     /gene="rhlE"
                     /locus_tag="IRB70_000070"
     CDS             complement(71658..73019)
                     /gene="rhlE"
                     /locus_tag="IRB70_000070"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlE"
                     /protein_id="HBC0630033.1"
                     /translation="MSFDSLGLSPDILRAVAEQGYREPTPIQQQAIPAVLEGRDLMAS
                     AQTGTGKTAGFTLPLLQHLITRQPHAKGRRPVRALILTPTRELAAQIGENVRDYSKYL
                     NIRSLVVFGGVSINPQMMKLRGGVDVLVATPGRLLDLEHQNAVKLDQVEILVLDEADR
                     MLDMGFIHDIRRVLTKLPAKRQNLLFSATFSDDIKALAEKLLHNPLEIEVARRNTASD
                     QVTQHVHFVDKKRKRELLSHMIGKGNWQQVLVFTRTKHGANHLAEQLNKDGIRSAAIH
                     GNKSQGARTRALADFKSGDIRVLVATDIAARGLDIEELPHVVNYELPNVPEDYVHRIG
                     RTGRAAATGEALSLVCVDEHKLLRDIEKLLKKEIPRIAIPGYEPDPSIKAEPIQNGRQ
                     QRGGGRGQGGGRGQQQPRRAESGAKSGNAKPAEKPSRRPGDAKPAGEQQRRRRPRKPA
                     AAQ"
     gene            73248..73919
                     /gene="cecR"
                     /locus_tag="IRB70_000071"
     CDS             73248..73919
                     /gene="cecR"
                     /locus_tag="IRB70_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415317.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CecR"
                     /protein_id="HBC0630034.1"
                     /translation="MNNPAMTIKGEQAKKQLIAAALAQFGEYGMNATTREIASQAGQN
                     IAAITYYFGSKEDLYLACAQWIADFIGEQFRPHAEEAERLFAQPQPDRAAIRELILRA
                     CRNMIKLLTQDDTVNLSKFISREQLSPTAAYHLVHEQVISPLHSHLTRLIAAWTGCDA
                     NDTRMILHTHALIGEILAFRLGKETILLRTGWTAFDEEKTELINQTVTCHIDLILQGL
                     SQRSL"
     gene            73922..74917
                     /gene="hlyD"
                     /locus_tag="IRB70_000072"
     CDS             73922..74917
                     /gene="hlyD"
                     /locus_tag="IRB70_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308900.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secretion protein HlyD"
                     /protein_id="HBC0630035.1"
                     /translation="MKKPVVIGLAVVVLAAVVAGGYWWYQSRQDNGLTLYGNVDIRTV
                     NLSFRVGGRVESLAVDEGDAVKAGQVLGELDHKPYEIALMQAKAGVSVAQAQYDLMLA
                     GYRDEEIAQAAAAVKQAQAAYDYAQNFYNRQQGLWKSRTISANDLENARSSRDQAQAT
                     LKSAQDKLRQYRSGNREQDIAQAKASLEQAQAQLAQAELNLQDSTLIAPSDGTLLTRA
                     VEPGTVLNEGGTVFTVSLTRPVWVRAYVDERNLDQAQPGRKVLLYTDGRPDKPYHGQI
                     GFVSPTAEFTPKTVETPDLRTDLVYRLRIVVTDADDALRQGMPVTVQFGDEAGHE"
     gene            74910..76646
                     /locus_tag="IRB70_000073"
     CDS             74910..76646
                     /locus_tag="IRB70_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415315.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0630036.1"
                     /translation="MNDAVITLNGLEKRFPGMDKPAVAPLDCTIHAGYVTGLVGPDGA
                     GKTTLMRMLAGLLKPDSGSATVIGFDPIKNDAALHAVLGYMPQKFGLYEDLTVMENLN
                     LYADLRSVTGEARKQTFARLLEFTSLGPFTGRLAGKLSGGMKQKLGLACTLVGEPKVL
                     LLDEPGVGVDPISRRELWQMVHELAGEGMLILWSTSYLDEAEQCRDVLLMNEGELLYQ
                     GEPKALTQTMAGRSFLMTSPHEGNRKLLQRALKLPQVSDGMIQGKSVRLILKKEATPD
                     DIRHADGMPEININETTPRFEDAFIDLLGGAGTSESPLGAILHTVEGTPGETVIEAKE
                     LTKKFGDFAATDHVNFAVKRGEIFGLLGPNGAGKSTTFKMMCGLLVPTSGQALVLGMD
                     LKESSGKARQHLGYMAQKFSLYGNLTVEQNLRFFSGVYGLRGRAQNEKISRMSEAFGL
                     KSIASHATDELPLGFKQRLALACSLMHEPDILFLDEPTSGVDPLTRREFWLHINSMVE
                     KGVTVMVTTHFMDEAEYCDRIGLVYRGKLIASGTPDDLKAQSANDEQPDPTMEQAFIQ
                     LIHDWDKEHGNE"
     gene            76639..77772
                     /locus_tag="IRB70_000074"
     CDS             76639..77772
                     /locus_tag="IRB70_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0630037.1"
                     /translation="MSNPILSWRRVRALCVKETRQIVRDPSSWLIAVVIPLLLLFIFG
                     YGINLDSSKLRVGILLEQRSEAALDFTHTMTGSPYIDATISDNRQELIAKMQAGKIRG
                     LVVIPVDFAEQMERANAIAPIQVITDGSEPNTANFVQGYVEGIWQIWQMQRAEDNGQT
                     FEPLIDVQTRYWFNPAAISQHFIIPGAVTIIMTVIGAILTSLVVAREWERGTMEALLS
                     TEITRTELLLCKLIPYYFLGMLAMLLCMLVSVFILGVPYRGSLLILFFISSLFLLSTL
                     GMGLLISTITRNQFNAAQVALNAAFLPSIMLSGFIFQIDSMPAVIRAVTYIIPARYFV
                     STLQSLFLAGNIPVVLVVNVLFLIASAVMFIGLTWLKTKRRLD"
     gene            77783..78889
                     /locus_tag="IRB70_000075"
     CDS             77783..78889
                     /locus_tag="IRB70_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0630038.1"
                     /translation="MFHRLWTLIRKELQSLLREPQTRAILILPVLIQVILFPFAATLE
                     VTNATIAIYDEDNGEHSVELTQRFARASAFTHVLLLKSPQEIRPTIDTQKALLLVRFP
                     ADFSRKLDTFQTAPLQLILDGRNSNSAQIAANYLQQIVKNYQQELLEGKPKPNNSELV
                     VRNWYNPNLDYKWFVVPSLIAMITTIGVMIVTSLSVAREREQGTLDQLLVSPLTTWQI
                     FIGKAVPALIVATFQATIVLAIGIWAYQIPFAGSLALFYFTMVIYGLSLVGFGLLISS
                     LCSTQQQAFIGVFVFMMPAILLSGYVSPVENMPVWLQNLTWINPIRHFTDITKQIYLK
                     DASLDIVWNSLWPLLVITATTGSAAYAMFRRKVM"
     gene            complement(78851..79261)
                     /locus_tag="IRB70_000076"
     CDS             complement(78851..79261)
                     /locus_tag="IRB70_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbhQ family protein"
                     /protein_id="HBC0630039.1"
                     /translation="MKWQQRVRVATGLSCWQIMLHLLVVALLVVGWMSKTLVHVGVGL
                     CALYCVTVVMMLVFQRHPEQRWREVADVLEELTTTWYFGAALIVLWLLSRVLENNFLL
                     AIAGLAILAGPAVVSLLAKDKKLHHLTSKHRVRR"
     gene            79394..80155
                     /locus_tag="IRB70_000077"
     CDS             79394..80155
                     /locus_tag="IRB70_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBC0630040.1"
                     /translation="MPDQTQQFSFKVLTINIHKGFTAFNRRFILPELRDAVRTVSADI
                     VCLQEVMGAHEVHPLHVENWPDTSHYEFLADTMWSDFAYGRNAVYPEGHHGNAVLSRY
                     PIEHYENRDVSVDGAEKRGVLYCRIVPPMTGKAIHVMCVHLGLREAHRQAQLAMLAEW
                     VNELPDGEPVLVAGDFNDWRQKANHPLKVQAGLDEIFTRAHGRPARTFPVQFPLLRLD
                     RIYVKNASASAPTALPLRTWRHLSDHAPLSAEIHL"
     gene            80152..81393
                     /gene="clsB"
                     /locus_tag="IRB70_000078"
     CDS             80152..81393
                     /gene="clsB"
                     /locus_tag="IRB70_000078"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsB"
                     /protein_id="HBC0630041.1"
                     /translation="MKCSWREGNKIQLLENGEQYYPAVFKAIGEAQERIILETFIWFE
                     DDVGKQLHAALLAAAQRGVKAEVLLDGYGSPDLSDEFVNELTAAGVVFRYYDPRPRLF
                     GMRTNVFRRMHRKIVVIDALIAFIGGLNYSAEHMSSYGPEAKQDYAVRLEGPIVEDIL
                     QFELENLPGQSAARRWWRRHHKAEENRQPGEAQVLLVWRDNEEHRDDIERHYLKMLTQ
                     ARREVIIANAYFFPGYRFLHALRKAARRGVRIKLIIQGEPDMPIVRVGARLLYNYLVK
                     GGVQVFEYRRRPLHGKVALMDDHWATVGSSNLDPLSLSLNLEANVIIHDRHFNQTLRD
                     NLNGIIAADCQQVDETMLPKRTWWNLTKSVLAFHFLRHFPALVGWLPAHTPRLAQVDP
                     PAQPTMETQDRVETENTGVKP"
     gene            81393..82349
                     /locus_tag="IRB70_000079"
     CDS             81393..82349
                     /locus_tag="IRB70_000079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0104 family protein"
                     /protein_id="HBC0630042.1"
                     /translation="MSKSHPRWRLAKKLLTWLFFIAVIVLLVVYAKKVDWEEVWKVIR
                     DYNRVALLSAVGLVVVSYLIYGCYDLLARFYCGHKLAKRQVMLVSFICYAFNLTLSTW
                     VGGIGMRYRLYSRLGLPGSTITRIFSLSITTNWLGYILLAGVIFTAGVVELPDHWYVD
                     QTTLRILGIGLLMIIAVYLWFCAFAKHRHMTIKGQKLVLPSWKFALAQMLISSVNWMV
                     MGAIIWLLLGQSVNYFFVLGVLLVSSIAGVIVHIPAGIGVLEAVFIALLAGEHTSKGT
                     IIAALLAYRVLYYFIPLLLALVCYLVLESQAKKLRAKNEAAM"
     gene            complement(82385..83098)
                     /locus_tag="IRB70_000080"
     CDS             complement(82385..83098)
                     /locus_tag="IRB70_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706665.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBC0630043.1"
                     /translation="MESFSQNSNKLDFQHEARILNGIWLITALGLVATAGLAWGAKYL
                     EITATKYDSPQMYIAIGLLLLCMYGLSKDINKINAAIAGVIYLFLISLVAIVVASLAP
                     VSAIIVVFSTAGSMFLISMLAGLLFKFDPGSHRFIIMMTLAGLALVIIVNATLMSERP
                     IWVISCLMIVLWSGIISHGRNKLLELTGKSHSEELWSPVRCAFIGALTLYYYFIGFFG
                     ILAAIAITLVWQRHTRFFH"
     gene            complement(83306..84010)
                     /locus_tag="IRB70_000081"
     CDS             complement(83306..84010)
                     /locus_tag="IRB70_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBC0630044.1"
                     /translation="MDRFPRSDSIVQTRTGLQTYMAQVYGWMTVGLLLTAFVAWYAAN
                     SAAVMELLFTNRIFLIGLVIAQLALVIVLSAMIQKLSAGVTTMLFMLYSALTGLTLSS
                     IFIVYTAASIASTFVVTAGMFGAMSLYGYTTKRDLSGFGNMLFMALIGIVLASLVNFW
                     LKSEALMWAVTYIGVIVFVGLTAYDTQKLKNMGEQIDTRDTSNLRKYSILGALTLYLD
                     FINLFLMLLRIFGNRR"
     gene            complement(84147..84599)
                     /gene="moaE"
                     /locus_tag="IRB70_000082"
     CDS             complement(84147..84599)
                     /gene="moaE"
                     /locus_tag="IRB70_000082"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase catalytic subunit MoaE"
                     /protein_id="HBC0630045.1"
                     /translation="MAETKIVIGPQPFSVGEEYPWLAERDEDGAVVTFTGKVRNHNLG
                     DSVKALTLEHYPGMTEKALAEIVDEARNRWPLGRVTVIHRIGELWPGDEIVFVGVTSA
                     HRSSAFEAGQFIMDYLKTRAPFWKREATPEGDRWVEARESDQQAAKRW"
     gene            complement(84601..84846)
                     /gene="moaD"
                     /locus_tag="IRB70_000083"
     CDS             complement(84601..84846)
                     /gene="moaD"
                     /locus_tag="IRB70_000083"
                     /EC_number="2.8.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin synthase sulfur carrier subunit"
                     /protein_id="HBC0630046.1"
                     /translation="MIKVLFFAQVRELVGTDATEVAADFPTVEALRQHLAAQSDRWAL
                     ALEDGKLLAAVNQTLVSFDHPLTDGDEVAFFPPVTGG"
     gene            complement(84839..85324)
                     /gene="moaC"
                     /locus_tag="IRB70_000084"
     CDS             complement(84839..85324)
                     /gene="moaC"
                     /locus_tag="IRB70_000084"
                     /EC_number="4.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic pyranopterin monophosphate synthase MoaC"
                     /protein_id="HBC0630047.1"
                     /translation="MSQLTHINAAGEAHMVDVSAKAETVREARAEAFVTMRSETLAMI
                     IDGRHHKGDVFATARIAGIQAAKRTWDLIPLCHPLMLSKVEVNLQAEPEHNRVRIETL
                     CRLTGKTGVEMEALTAASVAALTIYDMCKAVQKDMVIGPVRLLAKSGGKSGDFKVEAD
                     D"
     gene            complement(85327..85839)
                     /gene="moaB"
                     /locus_tag="IRB70_000085"
     CDS             complement(85327..85839)
                     /gene="moaB"
                     /locus_tag="IRB70_000085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor biosynthesis protein B"
                     /protein_id="HBC0630048.1"
                     /translation="MSQVSTEFIPTRIAILTVSNRRGEEDDTSGHYLRDSAQEAGHHV
                     VDKAIVKENRYAIRAQVSAWIASDDVQVVLITGGTGLTEGDQAPEALLPLFDREVEGF
                     GEVFRMLSFEEIGTSTLQSRAVAGVANKTLIFAMPGSTKACRTAWENIIAPQLDARTR
                     PCNFHPHLKK"
     gene            complement(85861..86850)
                     /gene="moaA"
                     /locus_tag="IRB70_000086"
     CDS             complement(85861..86850)
                     /gene="moaA"
                     /locus_tag="IRB70_000086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP 3',8-cyclase MoaA"
                     /protein_id="HBC0630049.1"
                     /translation="MASQLTDAFARKFYYLRLSITDVCNFRCTYCLPDGYKPSGVTNK
                     GFLTVDEIRRVTRAFASLGTEKVRLTGGEPSLRRDFTDIIAAVRENDAIRQIAVTTNG
                     YRLERDVANWRDAGLTGINVSVDSLDARQFHAITGQDKFNQVMAGIDAAFEAGFEKVK
                     VNTVLMRDVNHHQLDTFLNWIQHRPIQLRFIELMETGEGSELFRKHHISGQVLRDELL
                     RRGWIHQLRQRSDGPAQVFCHPDYAGEIGLIMPYEKDFCATCNRLRVSSIGKLHLCLF
                     GEGGVNLRDLLEDDTQQQALEARISAALREKKQTHFLHQNNTGITQNLSYIGG"
     regulatory      complement(86838..86982)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01055"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="molybdenum cofactor riboswitch; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="molybdenum cofactor"
                     /db_xref="RFAM:RF01055"
     gene            87247..88155
                     /gene="yvcK"
                     /locus_tag="IRB70_000087"
     CDS             87247..88155
                     /gene="yvcK"
                     /locus_tag="IRB70_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine diphosphate-N-acetylglucosamine-binding
                     protein YvcK"
                     /protein_id="HBC0630050.1"
                     /translation="MRNRTLADLDRVVALGGGHGLGRVLSSLSSLGSRLTGIVTTTDN
                     GGSTGRIRRSEGGIAWGDMRNCLNQLITEPSVASAMFEYRFGGNGELSGHNLGNLMLK
                     ALDHLSVRPLEAINLIRNLLKVDAHLIPMSEHPVDLMAIDDQGHEVYGEVNIDQLTAP
                     IQELLLTPNVPATREAVHAISEADLIIIGPGSFYTSLMPILLLKEIAQALRRTPAPMV
                     YIGNLGRELSLPAANLKLESKLAIMEQYVGKKVIDAVVVGPKADVSAVNNRIVIQEVL
                     EASDIPYRHDRQLLHNALEKALQALG"
     gene            complement(88193..90214)
                     /gene="uvrB"
                     /locus_tag="IRB70_000088"
     CDS             complement(88193..90214)
                     /gene="uvrB"
                     /locus_tag="IRB70_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit B"
                     /protein_id="HBC0630051.1"
                     /translation="MSKPFKLNSAFKPSGDQPEAIRRLEEGLEDGLAHQTLLGVTGSG
                     KTFTIANVIADLQRPTMVLAPNKTLAAQLYGEMKEFFPENAVEYFVSYYDYYQPEAYV
                     PSSDTFIEKDASVNEHIEQMRLSATKAMLERRDVVVVASVSAIYGLGDPDLYLKMMLH
                     LTVGMIIDQRAILRRLAELQYARNDQAFQRGTFRVRGEVIDIFPAESDDIALRVELFD
                     EEVERLSLFDPLTGQIVSTIPRFTIYPKTHYVTPRERIVQAMEEIKEELAARRNVLLE
                     NNKLLEEQRLTQRTQFDLEMMNELGYCSGIENYSRFLSGRGPGEPPPTLFDYLPADGL
                     LVVDESHVTIPQIGGMYRGDRARKETLVEYGFRLPSALDNRPLKFEEFEALAPQTIYV
                     SATPGNYELEKSGGDVVDQVVRPTGLLDPIIEVRPVATQVDDLLSEIRQRAAINERVL
                     VTTLTKRMAEDLTEYLEEHGERVRYLHSDIDTVERMEIIRDLRLGEFDVLVGINLLRE
                     GLDMPEVSLVAILDADKEGFLRSERSLIQTIGRAARNVNGKAILYGDKITPSMAKAIG
                     ETERRREKQQKYNEEHGITPQGLNKKVVDILALGQNIAKTKAKGRGKSRPIVEPDNVP
                     MDMSPKALQQKIHELEGLMMQHAQNLEFEEAAQIRDQLHQLRELFIAAS"
     gene            complement(90793..91470)
                     /gene="bioD"
                     /locus_tag="IRB70_000089"
     CDS             complement(90793..91470)
                     /gene="bioD"
                     /locus_tag="IRB70_000089"
                     /EC_number="6.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HBC0630052.1"
                     /translation="MSKRYFVTGTDTEVGKTVASCALLQAAKAAGYRTAGYKPVASGS
                     EKTPKGLRNSDALALQRNSSLQLDYATVNPYTFAEPTSPHIISAQEGRPIEALVMSAG
                     LRALEQQADWVLVEGAGGWFTPLSDTFTFADWVTQEQLPVILVVGVKLGCINHAMLTA
                     QAILHAGLTLAGWVANDVTPPGKRHAEYMTTLTRMIPAPLLGEIPWLAENPENAATGK
                     YINLALM"
     gene            complement(91463..92218)
                     /gene="bioC"
                     /locus_tag="IRB70_000090"
     CDS             complement(91463..92218)
                     /gene="bioC"
                     /locus_tag="IRB70_000090"
                     /EC_number="2.1.1.197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonyl-ACP O-methyltransferase BioC"
                     /protein_id="HBC0630053.1"
                     /translation="MATVNKQAIAAAFGRAAAHYEQHADLQRQSADVLLAMLPQRKYT
                     HVLDAGCGPGWMSRHWRERHAQVTALDLSPPMLVQARQKDAADHYLAGDIESLPLATA
                     TFDLAWSNLAVQWCGNLSTALRELYRVVRPGGVVAFTTLVQGSLPELHQAWQAVDERP
                     HANRSLPPDEIEQSLNGLHYQHHIQPITLWFDDALSAMRSLKGIGATHLHEGRDPRIL
                     TRSQLQRLQLAWPQKQGRYPLTYHLFLGVIARE"
     gene            complement(92205..93359)
                     /gene="bioF"
                     /locus_tag="IRB70_000091"
     CDS             complement(92205..93359)
                     /gene="bioF"
                     /locus_tag="IRB70_000091"
                     /EC_number="2.3.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-amino-7-oxononanoate synthase"
                     /protein_id="HBC0630054.1"
                     /translation="MSWQEKINAALDARRAADALRRRYPVAQGAGRWLVADDRQYLNF
                     SSNDYLGLSHHPQIIRAWKQSAEQFGVGSGGSGHVSGYSVAHQALEEELAEWLGYSRA
                     LLFISGFAANQAVIAAMMAKEDRIVADRLSHASLLEAASLSPSQLRRFAHNDVTHLAR
                     LLASPCPGQQLVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDDAHGTGVIGEQGRG
                     SCWLQKVKPELLVVTFGKGFGVSGAAVLCSSTVADYLLQFARHLIYSTSMPPAQAQAL
                     RASLAVIRSDEGDARREKLVSLIARFRAGVQDLPFTLADSWSAIQPLIVGDNSRALQL
                     AEKLRQQGCWVTAIRPPTVPAGTARLRLTLTAAHEMQDIDRLLEVLHGNG"
     gene            complement(93356..94396)
                     /gene="bioB"
                     /locus_tag="IRB70_000092"
     CDS             complement(93356..94396)
                     /gene="bioB"
                     /locus_tag="IRB70_000092"
                     /EC_number="2.8.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin synthase BioB"
                     /protein_id="HBC0630055.1"
                     /translation="MAHRPRWTLSQVTELFEKPLLDLLFEAQQVHRQHFDPRQVQVST
                     LLSIKTGACPEDCKYCPQSSRYKTGLEAERLMEVEQVLESARKAKAAGSTRFCMGAAW
                     KNPHERDMPYLEQMVQGVKAMGLEACMTLGTLSESQAQRLANAGLDYYNHNLDTSPEF
                     YGNIITTRTYQERLDTLEKVRDAGIKVCSGGIVGLGETVKDRAGLLLQLANLPTPPES
                     VPINMLVKVKGTPLADNDDVDAFDFIRTIAVARIMMPTSYVRLSAGREQMNEQTQAMC
                     FMAGANSIFYGCKLLTTPNPEEDKDLQLFRKLGLNPQQTAVLAGDNEQQQRLEQALMT
                     PDTDEYYNAAAL"
     gene            94483..95772
                     /gene="bioA"
                     /locus_tag="IRB70_000093"
     CDS             94483..95772
                     /gene="bioA"
                     /locus_tag="IRB70_000093"
                     /EC_number="2.6.1.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine--8-amino-7-oxononanoate
                     transaminase"
                     /protein_id="HBC0630056.1"
                     /translation="MTTDDLAFDQRHIWHPYTSMTSPLPVYPVASAEGCELILSDGRR
                     LVDGMSSWWAAIHGYNHPQLNAAMKSQIDAMSHVMFGGITHAPAIELCRKLVAMTPQP
                     LECVFLADSGSVAVEVAMKMALQYWQAKGEARQRFLTFRNGYHGDTFGAMSVCDPDNS
                     MHSLWKGYLPENLFAPAPQSRMDGEWDERDMVGFARLMAAHRHEIAAVIIEPIVQGAG
                     GMRMYHPEWLKRIRKMCDREGILLIADEIATGFGRTGKLFACEHAEIAPDILCLGKAL
                     TGGTMTLSATLTTREVAETISNGEAGCFMHGPTFMGNPLACAAANASLAIIESGDWQH
                     QVAAIEAQLREQLAPACDAEMVADVRVLGAIGVVETTRPVNMAALQKFFVEQGVWIRP
                     FGKLIYLMPPYIILPQQLQRLTAAVNRAVQDETFFCQ"
     gene            95831..96307
                     /locus_tag="IRB70_000094"
     CDS             95831..96307
                     /locus_tag="IRB70_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase inhibitor"
                     /protein_id="HBC0630057.1"
                     /translation="MKLISNDLRDGDKLPHRHVFNGMGYDGDNISPHLAWDDVPVGTK
                     SFVVTCYDPDAPTGSGWWHWVVVNLPADTRVLPQGFGSGLVAMPDGVLQTRTDFGKTG
                     YDGAAPPKGETHRYIFTVHALDVERIDVDEGASGAMVGFNVHFHSLASASITAMFS"
     gene            96459..97742
                     /locus_tag="IRB70_000095"
     CDS             96459..97742
                     /locus_tag="IRB70_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative acyl-CoA thioester hydrolase"
                     /protein_id="HBC0630058.1"
                     /translation="MNTFSVSRLALALAFGVTLTACSSTPPDQRPSDQTAPGTSSRPI
                     LSAKEAQNFDAQHYFASLTPGAAAWNPSPITLPAQPDFVVGPAGTQGVTHTTIQAAVD
                     AAIIKRTNKRQYIAVMPGEYQGTVYVPAAPGGITLYGTGEKPIDVKIGLSLDGGMSPA
                     DWRHDVNPRGKYMPGKPAWYMYDSCQSKRSDSIGVLCSAVFWSQNNGLQLQNLTIENT
                     LGDSVDAGNHPAVALRTDGDKVQINNVNILGRQNTFFVTNSGVQNRLETNRQPRTLVT
                     NSYIEGDVDIVSGRGAVVFDNTEFRVVNSRTQQEAYVFAPATLSNIYYGFLAVNSRFN
                     ASGDGVAQLGRSLDVDANTNGQVVIRDSAINEGFNTAKPWADAVISNRPFAGNTGNVD
                     DNDEVQRNLNDTNYNRMWEYNNRGVGSKVVAEAKK"
     gene            complement(97813..100074)
                     /locus_tag="IRB70_000096"
     CDS             complement(97813..100074)
                     /locus_tag="IRB70_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415292.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydratase"
                     /protein_id="HBC0630059.1"
                     /translation="MIKLSEKGVFLASNNEIIAEEYFTGEIKKEEAKKGTIAWSILSS
                     HNTSGNMDKLKIKFDSLASHDITFVGIVQTAKASGMERFPLPYVLTNCHNSLCAVGGT
                     INGDDHVFGLSAAQRYGGIFVPPHIAVIHQYMREMMAGGGKMILGSDSHTRYGALGTM
                     AVGEGGGELVKQLLNDTWDIDYPGVVAVHLTGKPALYVGPQDVALAIIGAVFKNGYVK
                     NKVMEFVGPGVAALSTDFRNSVDVMTTETTCLSSVWQTDEEVHNWLALHGRGQDYCQL
                     NPQPMAYYDGCISVDLSAIKPMIALPFHPSNVYEIDTLNQNLTDILREIEIESERVAH
                     GKARLSLLDKVENGRLKVQQGIIAGCSGGNYENVIAAANALRGQSCGNDTFSLAVYPS
                     SQPVFMDLAKKGVVADLIGAGAIIRTAFCGPCFGAGDTPINNGLSIRHTTRNFPNREG
                     SKPANGQMSAVALMDARSIAATAANGGYLTSASELDCWDNVPEYAFDVTPYKNRVYQG
                     FVKGATQQPLIYGPNIKDWPELGALTDNIVLKVCSKILDEVTTTDELIPSGETSSYRS
                     NPIGLAEFTLSRRDPGYVGRSKATAELENQRLAGNVSELTEVFARIKQIAGQEHIDPL
                     QTEIGSMVYAVKPGDGSAREQAASCQRVIGGLANIAEEYATKRYRSNVINWGMLPLQM
                     AEAPNFDVGDYIYIPGIKAALDNPGTTFKGYVIHEDAPVTEITLYMESLTAEEREIIK
                     AGSLINFNKNRQM"
     gene            complement(100257..101690)
                     /locus_tag="IRB70_000097"
     CDS             complement(100257..101690)
                     /locus_tag="IRB70_000097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anion permease"
                     /protein_id="HBC0630060.1"
                     /translation="MNKKSLWKLILILAIPCIIGFMPAPAGLSELAWVLFGIYLAAIV
                     GLVIKPFPEPVVLLIAVAASMVVVGNLSGGEFKTTAVLSGYSSGTTWLVFSAFTLSAA
                     FVTTGLGKRIAYLLIGKIGSTTLGLGYVTVFLDLVLAPATPSNTARAGGIVLPIINSV
                     AVALGSEPEKSPRRVGHYLMMSIYMVTKTTSYMFFTAMAGNILALKMINDILHLQISW
                     GGWALAAGLPGIIMLLVTPLVIYTMYPPEIKKVDNKTIAKAGLAELGPMKIREKMLLG
                     VFVLALLGWIFSKSLGVDESTVAIVVMATMLLLGIVTWEDVVKNKGGWNTLIWYGGII
                     GLSSLLSKVKFFEWLAEVFKNNLAFDGHGNVAFFVIIFLSIIVRYFFASGSAYIVAML
                     PVFAMLANVSGAPLMLTALALLFSNSYGGMVTHYGGAAGPVIFGVGYNDIKSWWLVGA
                     VLTILTFLVHITLGVWWWNMLIGWNML"
     gene            complement(101766..102818)
                     /locus_tag="IRB70_000098"
     CDS             complement(101766..102818)
                     /locus_tag="IRB70_000098"
                     /EC_number="5.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalomesaconate tautomerase"
                     /protein_id="HBC0630061.1"
                     /translation="MKKIPCVMMRGGTSRGAFLLAEHLPEDQTQRDKILMAIMGSGND
                     LEIDGIGGGNPLTSKVAIISRSSDPRADVDYLFAQVIVHEQRVDTTPNCGNMLSGVGA
                     FAIENGLIAATSPVTRVRIRNVNTGTFIEADVQTPNGVVEYEGSARIDGVPGTAAPVA
                     LTFLNAAGTKTGKVFPTDNQIDYFDDVPVTCIDMAMPVVIIPAEYLGKTGYELPAELD
                     ADKALLARIESIRLQAGKAMGLGDVSNMVIPKPVLISPAQKGGAINVRYFMPHSCHRA
                     LAITGAIAISSSCALEGTVTRQIVPSVGYGNINIEHPSGALDVHLSNEGQDATTLRAS
                     VIRTTRKIFSGEVYLP"
     gene            103002..103955
                     /locus_tag="IRB70_000099"
     CDS             103002..103955
                     /locus_tag="IRB70_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308823.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0630062.1"
                     /translation="MKHELSSMKAFVILAESSSFNNAAKLLNITQPALTRRIKKMEED
                     LHIQLFERTTRKVTLTKAGKRLLPEARELIKKFDETLFNIRDMNAYHRGMVTLACIPT
                     AVFYFLPLAIGKFNELYPNIKVRILEQGTNNCMESVLCNESDFGINMNNVTNSSIDFT
                     PLVNEPFVLACRRDHPLAKKQLVEWQELVGYKMIGVRSSSGNRLLIEQQLADKPWKLD
                     WFYEVRHLSTSLGLVEAGLGISALPGLAMPHAPYSSIIGIPLVEPVIRRTLGIIRRKD
                     AVLSPAAERFFALLINLWTDDKDNLWTNIVERQRHALQEIG"
     gene            complement(103996..104991)
                     /gene="pgl"
                     /locus_tag="IRB70_000100"
     CDS             complement(103996..104991)
                     /gene="pgl"
                     /locus_tag="IRB70_000100"
                     /EC_number="3.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconolactonase"
                     /protein_id="HBC0630063.1"
                     /translation="MKQTVYIASPESQQIHVWNLNHEGALTLTQVVDVPGQVQPMVVS
                     PDKRYLYVGVRPEFRVLAYRIAPDDGALTFAAESALPGSPTHISTDHQGQFVFVGSYN
                     AGNVSVTRLEDGLPVGVVDVVEGLDGCHSANISPDNRTLWVPALKQDRICLFTVSEDG
                     HLVAQDPAEVTTVEGAGPRHMVFHPNEQYAYCVNELNSSVDVWELKDPHGNIECVQTL
                     DMMPENFSDTRWAADIHITPDGRHLYACDRTASLITVFSVSEDGSVLSKEGFQPTETQ
                     PRGFNVDHSGKYLIAAGQKSHHISVYEIVGEQGLLHEKGRYAVGQGPMWVVVNAH"
     gene            105146..105964
                     /gene="ybhA"
                     /locus_tag="IRB70_000101"
     CDS             105146..105964
                     /gene="ybhA"
                     /locus_tag="IRB70_000101"
                     /EC_number="3.1.3.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyridoxal
                     phosphate/fructose-1,6-bisphosphate phosphatase"
                     /protein_id="HBC0630064.1"
                     /translation="MTTRVIALDLDGTLLTPKKTLLPSSIEALARAREAGYRLIIVTG
                     RHHVAIHPFYQALALDTPAICCNGTYLYDYHAKTVLEADPMPVNKALQLIEMLNEHHI
                     HGLMYVDDAMVYEHPTGHVIRTSNWAQTLPPEQRPTFTQVASLAETAQQVNAVWKFAL
                     THDDLPQLQHFGKHVEHELGLECEWSWHDQVDIARGGNSKGKRLTKWVEAQGWSMENV
                     VAFGDNFNDISMLEAAGTGVAMGNADDAVKARANIVIGDNTTDSIAQFIYSHLI"
     gene            complement(105965..107023)
                     /gene="modC"
                     /locus_tag="IRB70_000102"
     CDS             complement(105965..107023)
                     /gene="modC"
                     /locus_tag="IRB70_000102"
                     /EC_number="7.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum ABC transporter ATP-binding protein
                     ModC"
                     /protein_id="HBC0630065.1"
                     /translation="MLELNFSQTLGNHCLTINETLPANGITAIFGVSGAGKTSLINAI
                     SGLTRPQKGRIVLNGRVLNDAEKGICLTPEKRRVGYVFQDARLFPHYKVRGNLRYGMA
                     KSMVNQFDKLVALLGIEPLLDRLPGGLSGGEKQRVAIGRALLTAPELLLLDEPLASLD
                     IPRKRELLPYLQRLTREINIPMLYVSHSLDEILHLADRVMVLENGQVKAFGALEEVWG
                     SSVMNPWLPKEQQSSILKVTVLEHHPHYAMTALALGDQHLWVNKLDEPLQAALRIRIQ
                     ASDVSLVLQPPQQTSIRNVLRAKVVNSYDDNGQVEVELEVGGKTLWARISPWARDELA
                     IKPGLWLYAQIKSVSITA"
     gene            complement(107026..107715)
                     /gene="modB"
                     /locus_tag="IRB70_000103"
     CDS             complement(107026..107715)
                     /gene="modB"
                     /locus_tag="IRB70_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter permease subunit"
                     /protein_id="HBC0630066.1"
                     /translation="MILTDPEWQAVLLSLKVSSLAVLFSLPFGIFFAWLLVRCTFPGK
                     ALLDSVLHLPLVLPPVVVGYLLLVSMGRRGFIGERLYDWFGLSFAFSWRGAVLAAAVM
                     SFPLMVRAIRLALEGVDIKLEQAARTLGAGRWRVFFTITLPLTLPGIIVGTVLAFARS
                     LGEFGATITFVSNIPGETRTIPSAMYTLIQTPGGESGAARLCIISIALAMISLLISEW
                     LARISRERAGR"
     gene            complement(107715..108488)
                     /gene="modA"
                     /locus_tag="IRB70_000104"
     CDS             complement(107715..108488)
                     /gene="modA"
                     /locus_tag="IRB70_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBC0630067.1"
                     /translation="MARKWLNLFTGAALSFAVAGNALADEGKITVFAAASLTNAMQDI
                     ATQYKKEKGVDVVSSFASSSTLARQIEAGAPADLFISADQKWMDYAVDKKAIDTASRQ
                     TLLGNSLVVVAPKASEQKDFTIDSKTNWTSLLNGGRLAVGDPEHVPAGIYAKEALQKL
                     GAWDTLSPKLAPAEDVRGALALVERNEAPLGIVYGSDAVASKGVKVVATFPEDSHKKV
                     EYPVAVVEGHNNATVKAFYDYLKGPQAAEIFKRYGFTTK"
     gene            complement(108655..108804)
                     /gene="acrZ"
                     /locus_tag="IRB70_000105"
     CDS             complement(108655..108804)
                     /gene="acrZ"
                     /locus_tag="IRB70_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux pump accessory protein AcrZ"
                     /protein_id="HBC0630068.1"
                     /translation="MLELLKSLVFAVIMVPVVMAIILGLIYGLGEVFNIFSGVGKKDQ
                     PGQNH"
     gene            108933..109721
                     /gene="modE"
                     /locus_tag="IRB70_000106"
     CDS             108933..109721
                     /gene="modE"
                     /locus_tag="IRB70_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum-dependent transcriptional regulator"
                     /protein_id="HBC0630069.1"
                     /translation="MQAEILLTLKLQQKLFADPRRISLLKHIALSGSISQGAKDAGIS
                     YKSAWDAINEMNQLSEHILVERATGGKGGGGAVLTRYGQRLIQLYDLLAQIQQKAFDV
                     LSDDDALPLNSLLAAISRFSLQTSARNQWFGTITARDHDDVQQHVDVLLADGKTRLKV
                     AITAQSGARLGLDEGKEVLILLKAPWVGITQDEAVAQNADNQLPGIISHIERGAEQCE
                     VLMALPDGQTLCATVPVNEATSLQQGQNVTAYFNADSVIIATLC"
     gene            109789..111261
                     /gene="modF"
                     /locus_tag="IRB70_000107"
     CDS             109789..111261
                     /gene="modF"
                     /locus_tag="IRB70_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdate ABC transporter ATP-binding protein
                     ModF"
                     /protein_id="HBC0630070.1"
                     /translation="MSSLQILQGTFRLGDTKTLQLPRLTLNAGDSWAFVGSNGSGKSA
                     LARALSGELPLLKGERQSQFSHITRLSFEQLQKLVSDEWQRNNTDMLSPGEDDTGRTT
                     AEIIQDEVKDTPRCMQLAQQFGITALLDRRFKYLSTGETRKTLLCQALMSEPDLLILD
                     EPFDGLDVASRQQLAELLASLHQSGITLVLVLNRFDEIPEFVQFAGVLADCTLAETGA
                     KEELLQQALVAQLAHSEQLEGVQLPEPDEPSARHALPANEPRIVLNNGVVSYNDRPIL
                     NNLSWQVNPGEHWQIVGPNGAGKSTLLSLITGDHPQGYSNDLTLFGRRRGSGETIWDI
                     KKHIGYVSSSLHLDYRVSTTVRNVILSGYFDSIGIYQAVSDRQQKLVQQWLDILGIDK
                     RTADAPFHSLSWGQQRLALIVRALVKHPTLLILDEPLQGLDPLNRQLIRRFVDVLISE
                     GETQLLFVSHHAEDAPACITHRLEFVPDGDFYRYALTKIN"
     gene            111522..112538
                     /gene="galE"
                     /locus_tag="IRB70_000108"
     CDS             111522..112538
                     /gene="galE"
                     /locus_tag="IRB70_000108"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308814.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBC0630071.1"
                     /translation="MRVLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVI
                     ERLGGKHPTFVEGDIRNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNNVN
                     GTLRLISAMRAANVKNFIFSSSATVYGDQPKIPYVESFPTGTPQSPYGKSKLMVEQIL
                     TDLQKAQPDWSIALLRYFNPVGAHPSGDMGEDPQGIPNNLMPYIAQVAVGRRDSLAIF
                     GNDYPTEDGTGVRDYIHVMDLADGHVVAMEKLANKPGVHIYNLGAGVGSSVLDVVNAF
                     SKACGKPVNYHFAPRREGDLPAYWADASKADRELNWRVTRTLDEMAQDTWHWQSRHPQ
                     GYPD"
     gene            112548..113594
                     /gene="galT"
                     /locus_tag="IRB70_000109"
     CDS             112548..113594
                     /gene="galT"
                     /locus_tag="IRB70_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-phosphate uridylyltransferase"
                     /protein_id="HBC0630072.1"
                     /translation="MTQFNPVDHPHRRYNPLTGQWILVSPHRAKRPWQGAQETPAKQV
                     LPAHDPNCFLCAGNVRVTGDKNPDYTGTYVFTNDFAALMSDTPDAPESNDPLMGCQSA
                     RGTSRVICFSPDHSKTLPELSVAALTEIVKTWQEQTAELGKTYPWVQVFENKGAAMGC
                     SNPHPHGQIWANSFLPNEAEREDRLQKEYFAGQKSPMLVDYVQRELADGSRTVVETEH
                     WLAVVPYWAAWPFETLLLPKAHVLRITDLTDAQRSDLALALKKLTSRYDNLFQCSFPY
                     SMGWHGAPFNGEENQHWQLHAHFYPPLLRSATVRKFMVGYEMLAETQRDLTAEQAAER
                     LRAVSDIHFRESGV"
     gene            113598..114746
                     /gene="galK"
                     /locus_tag="IRB70_000110"
     CDS             113598..114746
                     /gene="galK"
                     /locus_tag="IRB70_000110"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001713229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBC0630073.1"
                     /translation="MSLKEKTQSLFANAFGYPATHTIQAPGRVNLIGEHTDYNDGFVL
                     PCAIDYQTVISCAPRDDRKVRVMAADYENQLDEFSLDAPIVAHESYQWANYVRGVVKH
                     LQLRNNSFGGVDMVISGNVPQGAGLSSSASLEVAVGTVLQQLYHLPLDGAQIALNGQE
                     AENQFVGCNCGIMDQLISALGKKDHALLIDCRSLGTKAVSMPKGVAVVIINSNFKRTL
                     VGSEYNTRREQCETGARFFQQPALRDVTIEEFNAVAHELDPIVAKRVRHILTENARTV
                     EAASALEQGDLKRMGELMAESHASMRDDFEITVPQIDTLVEIVKAVIGDKGGVRMTGG
                     GFGGCIVALIPEELVPAVQQAVAEQYEAKTGIKETFYVCKPSQGAGQC"
     gene            114740..115780
                     /gene="galM"
                     /locus_tag="IRB70_000111"
     CDS             114740..115780
                     /gene="galM"
                     /locus_tag="IRB70_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-1-epimerase"
                     /protein_id="HBC0630074.1"
                     /translation="MLNETPALAPDGQPYRLLTLRNNAGMVVTLMDWGATLLSARIPL
                     SDGSVREALLGCASPECYQDQAAFLGASIGRYANRIANSRYTFDGETVTLSPSQGVNQ
                     LHGGPEGFDKRRWQIVNQNDRQVLFALSSDDGDQGFPGNLGATVQYRLTDDNRISITY
                     RATVDKPCPVNMTNHVYFNLDGEQSDARNHKLQILADEYLPVDEGGIPHDGLKSVAGT
                     SFDFRSAKIIASEFLADDDQRKVKGYDHAFLLQAKGDGKKVAAHVWSADEKLQLKVYT
                     TAPALQFYSGNFLGGTPSRGTEPYADWQGLALESEFLPDSPNHPEWPQPDCFLRPGEE
                     YSSLTEYQFIAQ"
     gene            115983..116735
                     /gene="gpmA"
                     /locus_tag="IRB70_000112"
     CDS             115983..116735
                     /gene="gpmA"
                     /locus_tag="IRB70_000112"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000301556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBC0630075.1"
                     /translation="MAVTKLVLVRHGESQWNKENRFTGWYDVDLSEKGVSEAKAAGKL
                     LKEEGYSFDFAYTSVLKRAIHTLWNVLDELDQAWLPVEKSWKLNERHYGALQGLNKAE
                     TAEKYGDEQVKQWRRGFAVTPPELTKDDERYPGHDPRYAKLSEKELPLTESLALTIDR
                     VIPYWNETILPRMKSGERVIIAAHGNSLRALVKYLDNMSEEEILELNIPTGVPLVYEF
                     DENFKPLKRYYLGNADEIAAKAAAVANQGKAK"
     gene            complement(116901..117953)
                     /gene="aroG"
                     /locus_tag="IRB70_000113"
     CDS             complement(116901..117953)
                     /gene="aroG"
                     /locus_tag="IRB70_000113"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroG"
                     /protein_id="HBC0630076.1"
                     /translation="MNYQNDDLRIKEIKELLPPVALLEKFPATENAANTVAHARKAIH
                     KILKGNDDRLLVVIGPCSIHDPVAAKEYATRLLALREELKDELEIVMRVYFEKPRTTV
                     GWKGLINDPHMDNSFQINDGLRIARKLLLDINDSGLPAAGEFLDMITPQYLADLMSWG
                     AIGARTTESQVHRELASGLSCPVGFKNGTDGTIKVAIDAINAAGAPHCFLSVTKWGHS
                     AIVNTSGNGDCHIILRGGKEPNYSAKHVAEVKDGLNKAGLPAQVMIDFSHANSSKQFK
                     KQMDVCADVCQQIAGGEKAIIGVMVESHLVEGNQSLESGEPLAYGKSITDACIGWDDT
                     DALLRQLANAVKARRG"
     gene            118269..118649
                     /locus_tag="IRB70_000114"
     CDS             118269..118649
                     /locus_tag="IRB70_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgS-like family protein"
                     /protein_id="HBC0630077.1"
                     /translation="MKMTKLATLFLTATLSLASGAALAADSGAQTNNGQANAAADAGQ
                     VAPDARENVAPNNVDNNGVNTGSGGTMLHSDGSSMNNDGMTKDEEHKNTMCKDGRCPD
                     INKKVQTGDGINNDVDTKTDGTTQ"
     gene            118763..119704
                     /gene="zitB"
                     /locus_tag="IRB70_000115"
     CDS             118763..119704
                     /gene="zitB"
                     /locus_tag="IRB70_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family zinc transporter ZitB"
                     /protein_id="HBC0630078.1"
                     /translation="MAHSHSHTSSHLPEDNNARRLLYAFGVTAGFMLVEVIGGFLSGS
                     LALLADAGHMLTDTAALLFALLAVQFSRRPPTIRHTFGWLRLTTLAAFVNAIALVVIT
                     ILIVWEAIERFRTPRPVEGGMMMAIAVAGLLANILSFWLLHHGSEEKNLNVRAAALHV
                     LGDLLGSVGAIIAALIIIWTGWTPADPILSILVSLLVLRSAWRLLKDSVNELLEGAPV
                     SLDIAELKRRMCREIPEVRNVHHVHVWMVGEKPVMTLHVQVIPPHDHDALLDQIQHYL
                     MDHYQIEHATIQMEYQPCHGPDCHLNEGVSGHSHHHH"
     gene            complement(119701..120420)
                     /gene="pnuC"
                     /locus_tag="IRB70_000116"
     CDS             complement(119701..120420)
                     /gene="pnuC"
                     /locus_tag="IRB70_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide riboside transporter PnuC"
                     /protein_id="HBC0630079.1"
                     /translation="MDFFSVQNILVHIPIGAGGYDLSWIEAVGTIAGLLCIGLASLEK
                     ISNYFFGLINVTLFGIIFFQIQLYASLLLQMFFFAANIYGWYAWSRQTSQNEAELKIR
                     WLPLPKALCWLAVCVVSIGLMTVFINPVFAFLTRVAVIIMQALGLQVAMPELQPDAFP
                     FWDSCMMVLSIVAMILMTRKYVENWLLWVIINVISVVIFALQGVYAMSLEYIILTFIA
                     LNGSRMWINSARERGSRALSH"
     gene            complement(120458..121501)
                     /gene="nadA"
                     /locus_tag="IRB70_000117"
     CDS             complement(120458..121501)
                     /gene="nadA"
                     /locus_tag="IRB70_000117"
                     /EC_number="2.5.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinolinate synthase NadA"
                     /protein_id="HBC0630080.1"
                     /translation="MSVMFDPEAAIYPFPPKPTPLSIDEKAYYREKIKRLLKERNAVM
                     VAHYYTDPEIQQLAEETGGCISDSLEMARFGAKHPASTLLVAGVRFMGETAKILSPEK
                     TILMPTLQAECSLDLGCPVEEFNAFCDAHPDHTVVVYANTSAAVKARADWVVTSSIAV
                     ELIDHLDSLGEKIIWAPDKHLGRYVQKQTGADILCWQGACIVHDEFKTQALTRLQEEY
                     PDAAILVHPESPQAIVDMADAVGSTSQLIAAAKTLPHQRLIVATDRGIFYKMQQAVPD
                     KELLEAPTAGEGATCRSCAHCPWMAMNGLQAIAEALEQEGSNHEVHVDERLRERALVP
                     LNRMLDFAATLRG"
BASE COUNT        30158 a        31953 c        30240 g        29455 t
ORIGIN      
        1 cagtaagttc aagtaaaaaa tactcagatc gtgctgagtg ggtattattc ctgaaggtgt
       61 actcaaacgc tgtgcttttt attgatataa aacatcatga taaaaacata gaaccaaatc
      121 ttttttctca aagagatttg gtagaaacat tcatacgcaa ctggccagaa gcagcagaaa
      181 tatttgaaat gaaaggtatt tcaggcttag cttgtattca tccaactaca gattcagata
      241 ttgcaaactt aagaaaaaat ggaataaatc tgcccgtagt gatggatgga aaagcatatg
      301 ccccattagg aatgggaata acaacagcgc gtaccgctgt gagcgtatca acttatcgaa
      361 ataaaatata tcattgtgct aagcacatag agaaaatatt tatggatgaa gatagtccat
      421 acataaaaga aataaaatct ctaggtgtaa acaatcctga attcaagatg catatgttta
      481 atgatggtgg gttaggtatt gttgagataa atactagaaa aggctggaaa ttccttagaa
      541 aaaatgctga tgcgtctcat gatgttttca gttttttaaa taacgcactg atgccagagt
      601 gggctagtcc tgttgtatta cagttctggg aaaaaactca ttgtaaaatg gagggaattg
      661 aaaattaata ctgaaatttg tatggctcac atctcccccc gaggtaaata gttattacgc
      721 agttctgtta ttggtataaa gtgggtgata acttatcaaa atggcctccc acctaacgcc
      781 tcgtttcact cgttgctcaa actagccccc atcagaatga accctactgg gggcaacgtt
      841 tcttaatgca gccagctatc gtcttcccac accttctgca taattttcat cacttgcttc
      901 ctttcttcgt ccagttgcag tccggtcagt tccacaccgt tagagctacc tttgcggata
      961 cgaattaccg tttttggata cagggggcgc agattgcggt aaagctcgga ttcaagggcg
     1021 tccaggatag actggctaat cttctgctct ttatcgatca ttatttcaat gcgcataaaa
     1081 gtcacctcaa ctgatgacat ccattgagcg gttgtattcg tgggttctga tttttgccat
     1141 gagttcatct gttagttcag aaacccactg caaagccagc cccttctctt catcactaca
     1201 ctcactagcc gctacaagct taagaaaaaa atcaatgcgc tggagcttca aagactccaa
     1261 aaaatagtcc tgcatttttc ctcctatgac accacaagta atactgtatg cataaccact
     1321 gtttatattt acagtatata ataatcttac tgatgtaaaa cgttttttta cgttcatcag
     1381 cctgatatgc ctggtattat taagagcacg aattgttaac ccgcgtaatt aatacaggtt
     1441 ccgccactta tcatcttcct gcaaacgctg gttccgatag aagattcgca ggcctgctcc
     1501 tgacggaatg ctgccgccgc gaaggagtaa atcgacctct ttctcgctgc catcaaatcc
     1561 tctggacttc agttcataga cgagctgctg tcgttgatgg tctgtaattc gctgtttgta
     1621 gtctctacgc cgtttcggtt tcaccaggcg taaccttgca gccagttccc ggcgctcttt
     1681 tttgttcata ctgtgcagat aatcgtgcaa ctccttgtca ttcatgcggg taatgtccgt
     1741 tctggtatcc ccatcagctg atttgtcttt cccttgttgg ttcaaatttt cagcaagggg
     1801 acagttattg ccacgagtcc aaggggcgca agcgccctgg tcggctgccg cctcctgaac
     1861 gtcaacggcc ttacgaacca ttttccactt cactgcatga gtgcagatct tgccctctgc
     1921 aatgggtgac cagatgccat aaatacgaat accgtgatcg ccataggcgg ttggctcttc
     1981 gttgatttca taagcggttc tgatgaggtg atatttgcgg ggaaccagta cgccgccctg
     2041 cttcatgatg taggtggcaa aacaaccagc atcagcagca gccagaatgg catcaagacg
     2101 cgggttatcc agtaccggcg cacctgcttt tttgtcaccc tgttgccttg ccgcctgacc
     2161 agccagcaat cgcagttcac ggtaagcctg acgccccgga atgccaaaga agcggaattg
     2221 ctgaacacga tgcagagacg cccaggcatt aacgtattca gcgttatcac gcagggattt
     2281 acccgtttcc ttactgatct cgccagccag accacgcccg tcaatattct tactgatata
     2341 tttcgcaatg tagcttgtcg gcgttccttt gcgcgggttt atcagctcag acttaaagcg
     2401 tggccccgtg ttattgccca gctcctcgcg gtcttcacgg atggcaaact tacgcaacaa
     2461 tgcagtaatg gcgcggcggt cttttttgcg catgaaacac aacaggtgcc agtgaactgt
     2521 gccgtcatga tgcggctcag ccacccgcac gccataccag cgcaacccgg ctttgtgcat
     2581 agccttacga aatgcagcaa acatgccgac cagataatcg ctgctttgtc ttactgtcgc
     2641 attggtccag gtcgggtttg gcctgccgtt atttagcgtg gaatggaaac gtgacggaca
     2701 ggtgatggtg tagaaaacgg cgcagtcacc gcgcatttcc gcgataagct ccagaccttt
     2761 aacacaggcc atcatctcat tgcggcggtg cgccgggttg ctgctgctgg cgtttaccac
     2821 gtcttccata tccagcgtgt cgccctcttc gttcaccagt tcatgagaac ggaaaaactc
     2881 cagtgacttg cggcgctgct cacgtttatg catcacggct tcatagctga catagggaga
     2941 tgcttttttg ctgaccaggc agacagcacg caactgctct tcccaccatt cgcaacgcat
     3001 tttccataat ttccggtacc accagtcggc gcacaacata cgcgccagcg aacccggaat
     3061 gagttcatag ggcacgggtt tacggcggtt tcttttccga cggagttgct caaacgcagg
     3121 cgggatgaca tccagacgca gggtttccgc tgccaccttt tcccatgtct tgcggatttc
     3181 ttctggctta acgtcatcgg tggcatacaa atcaccacaa gctgcatcaa ggcacatgct
     3241 catatgcgca gcgacaaggg tagacaggcg tttcacctga tcctgactca tttcaggcag
     3301 aatcagcagg ccgtccagcc ctacatggct tgccataaaa cgaaaagatg cagatagctg
     3361 gctgtcgcgt acatgctcca gtcgttccag acatggctta atcgtctcac gtaaatagcg
     3421 ggaataagcc tttggcctgc ccaggctgct gaagtattca atacgttgca tcagcggctt
     3481 gctgatatgg gagggctggg cgctgacgtc tgccagaatg accatgtccg ggttaaaacg
     3541 ctgctgctca tgcgccaact ttgcccggct aatgagctta tcctgctcca tttcgcgctg
     3601 gacaggatca cgggattcat taaagaaata acgctcccag acctgatcac tcagcgcctc
     3661 acggcgcagc tgttcctgct cgttatcggc agcgtacaga gtgatcaggt ttgaaagcgt
     3721 agaaaccggc gcaacttccg ccgggtccag ataagggtta atggcctttt tcgggctgtt
     3781 ccatgagaac gatgcggcag cttcgttaaa gccgcagcag ttgttcatat cggcatgact
     3841 catgcacgta ctccgtacac ggcagaacta tccacgccac gcgaataatc aaatcccacc
     3901 cagcagcgcg gcccagaaac agcaatgatt tctgttgctg atttaccctc gccagctgcc
     3961 acaccgatgc tgcgttttgc cttgatgtag tggtgagtaa aattgcgata cagcgaacgg
     4021 atcagggatg tgtcactgtt agaaacaatg accggatgtc cttctgatga ccgatgttca
     4081 agaacagatg ccaggtgata ctggtcatct tcagtgaagc cgtcagtgtg atagccggaa
     4141 aacgtaccgt catacggcgg atcgcaatac accacatccc ccgccttcaa catcgccagc
     4201 gtttcatcaa agctggcgca gataaacgtt gctcgctggg ccttttctgc aaatgcgcga
     4261 atttcttttt cagggaaata cggattttta taattaccgt agggaatgtt gaaatgcccg
     4321 ctcttgttat agcgacataa accacggtaa ccgtgacgat tgagatacag gaaatatacc
     4381 gctttcatga aatcagtaat ttcagttgag taattaaact cctgccttat gttgtaataa
     4441 gccacctccc tgtttgcgat ctcaaataaa actctggcgc gagatataaa cgattcacaa
     4501 tcagcggcaa cctttttata gaggttgatt aaatcaggat taatatccgc aaccagatag
     4561 ctgggataat ccgtctccat catcacagca caggaacccg cgaaaggttc aaccagtcgc
     4621 gggccagcag gaagatgttt tttcagttcg gacattatgg cagttttatt tcccgcccat
     4681 ttcaggatgg tgctcataca gcacctccgt tgtaatgttt gcctttcagc tctgcgattt
     4741 cctgacaggt aatgcaaagc tgcacacccg gaatggcacg gcggcgtgct ggcggaattg
     4801 gcgcttcaca ctcaatgcaa agcacgcggg acacgcccgg cgttttggca cgggcagcat
     4861 ggatatgacg ctggcgttct tcttcaacgc gctgctgtac gagatccatt gcatcagcca
     4921 ttagtggatc tcctgcgctt cgttctggat tgcttcagca gtcacacgaa gcagttctgc
     4981 cgcttcgacg tggtttagct ggcgggatgt gatatgacac gccaggctat caaggcgagc
     5041 tgccattgct tcagcccttg cccggcgttc ttccagacga gcctctgtca gtaaaatatt
     5101 aagccctgcg tcatccggtc cggttttggt cgtgagggtt tcaatattac gcataatcaa
     5161 ttctcctgaa tttagataaa gggatgcctg gctggtttac gccattaatt tcattagttg
     5221 gttaattcgg catggttagc cgtctgggaa ataagctcac cactgcacga aaatgattca
     5281 ttgctttaat caactcccgc ttttcgtcag tggtcagctc attaatgctg atgctatgac
     5341 gttcagctgg aatttttgcc ataaagaata tggcagccag tgcccgttta ttttgttcgc
     5401 tattaatatc ccgtggatca cgcatatctt taataaaccg ttcaagctct gactcaatat
     5461 tcagaccaaa aactttcgcc cttaactccg caatgtgatt aagtccattc aggcgttcac
     5521 cggggcttaa tggaacagtc gccgcagcgc cttcaatagc catttgttcc cccgtttttt
     5581 cgtagatagt tctgccagca attcatcttg tgaacggcac ggatgccagc gtttaccatc
     5641 ctcacccatg atccagccgt gaccgtagtg cattgccggg ctttgtttaa caagcagcga
     5701 tgcaaatgat ggttctttcg taagcataag cacctcacag caaaccgaat gaagcaccga
     5761 agccagtcac ggtatcaact gcactcgcca tcgcagggtt agcctgtaaa cgggcctgca
     5821 atgaaacagc agccagcgcc atcagtcgtg ttactgagtt aatgctgctg atagcatcac
     5881 gacgacctgc actggttttt acatcgccag ataccgcacc tgcagcaaca cgtccgatct
     5941 ctgcggttgc actcatgacg taatgcggca gtttctcttt tgctacctca ttaatcggta
     6001 cacatggcag gcagtgaatc tgtgccagaa aaccatctac cagcgttgaa tcttcagtca
     6061 gatcggtaag caaccaaatt tctggtgcgg ttaataaatg aggttgagct gggttcagtt
     6121 tgttccgcag aatctgcaca ttcatacctg cacgttctgc cagttgcacc agattgtggc
     6181 gcagtgcgaa tgcacgacag gcttcatcaa aatgtggatg tttggaaact tggtaatcaa
     6241 acatggtcga cacctctgat gtatcccaaa atggaactag ttgaatacaa cattgcaatc
     6301 agtaagtgca tcaacggtaa gagcagcaag gttgatcatt accttttctc ttttcttgtc
     6361 tttacgaaga cgatgccgag gaatgcgacc atccgccaac atatcgttga ttgtgtcgat
     6421 tgaaagacca gtaagttcgc tataacgctc gattgtgacg tgtggcgtat tcagagttat
     6481 tgaaatgtta ggggtcatga tgcaacatct cctattggct tgtggtgagc ctgtagtaat
     6541 cgtgacaagt acccaattgg gtacaaaact gatactagga tcgcaaaaga gatatgtcaa
     6601 catcaaagta cccaagtgag atcaaaataa atcccaataa aggtggtaag gctgcgattg
     6661 agcgattagt cgaagcctat ggctttacga cacgacaggc tttagctgat cacttggaag
     6721 tatcaaaaag cacactagcg aacaggtatt tgcgggatac atttcctgct gactggataa
     6781 tccaatgtgc tcttgaaaca ggaacctccc tcaaatggtt aactaccgga caaggcctta
     6841 agcaaagctc gctgacagca gctacagaag agcttgttaa gtttcgcctt gccgcaggca
     6901 aaatgattga agacggttca tatgtcttcg attcatcatt tcttcctgca aacctttcat
     6961 caccaattgt tattcaggat ggactcgtca catacatttg tgatcaaaaa ttttctgaag
     7021 tacttgatgg aaactggtta atcaatatcg acggaaccta ttccattcga aaaatcacaa
     7081 ggcttcctaa aggaatgatt aaaattacaa cagcagagaa tagctttgaa tgtgcatttt
     7141 ctgatattga agtggttgct tgtataagaa gtacaatagt ctcgaattaa tatagtaaaa
     7201 ggattttaaa atgaattcat ttgccatcgt tatagtctta ttagcatttc tcgcccctgt
     7261 tctagctgta atattattta aacaaagtaa aaaacacaaa gcggctatag ataacctgac
     7321 agctaacaac atagcccttt ctaaccaact gattgaaaat caagaaaaac tagcacagac
     7381 cgtacgagaa ttatcagagc ttgaagggcg agcagcacca ttgtggcaat acgaagaatt
     7441 gcacagcgca gtaatggatg cagagaataa gataaaaaat gcggactcaa tagccaagca
     7501 aaaaatagat gaagcccaaa ttaaggcggc taaaacagta aacgaagcaa attatcaagc
     7561 tcagataaca ataagcaacg ctaatagcga agctatagca atcaccaaag acgctcgcga
     7621 tgcacgcctg aaagccaaag aacgtcttga taatgctaat aataaagcaa atgagctaat
     7681 ctcaaatgct aatgacaatg cagtaaaaat tatttctgat gcagaagaaa gagcaaagga
     7741 gattgctggt tcagcatatg aagctaaaga gtttgcagaa aaatatgaag cagttgcaaa
     7801 atcaatgaaa aataaaattg aaggttatgg tgatgaatgg atcatcccta accgtagtgt
     7861 acttgatgag ctggcagaaa attatgaatt tacagatgca ggcaaggaat tacaaaaagc
     7921 cagagagtta accaaatcat taataaaaac taataaagct gcttcgtgtg attatgttga
     7981 gcaaaacagg cgtaatactg ccataaactt tgttttggat gccttcaatg gaagagttga
     8041 cagtatttta tcaaaagtca aacacaacaa ttttggaaaa ctttcccaag aaataaaaga
     8101 tgcatttcaa ctagtaaatt acaatggctc tgcctttagg tccgcaaaaa taagtgacat
     8161 ctatcttcag gcaagactca acgagctaaa atggggtgta gcagttaatg aaattatgct
     8221 cgaagaaaaa gaagagcaaa gaaggattaa agaacagctt cgtgaagagg aaagagctcg
     8281 tagagaatat gaaaaagcga taaaagaagc tgaaaaagaa gaaaaagcta ttcagcaagc
     8341 tataaataaa gcaacgaaag aacttatgct tgcaaatgaa gaacaacgct tagctttaga
     8401 gcaaaaaata gctgaactac agttaaaata tgaagaagct gaagctaaaa atcaacgagc
     8461 tatttctatg gcccaacaaa ccagatcagg ccacgtctat atcattagta atattggttc
     8521 atttggcgaa gatgtatata aaattggaat gacacgccgc cttgaaccac ttgatcgtgt
     8581 tcgtgaactc ggagatgcta gtgttccttt ttcgttcgat gttcatgcga tgatttatag
     8641 tgatgatgca ccatcattag aaaaccatct gcataaagtt ttcaatgaaa agcaggtcaa
     8701 taaaattaac tcacgaaaag agttttttaa cgtaaattta aaagaaatca aatcagttat
     8761 tgaagacatg aacatcaacg cccactggac aatgtttgca gaggcgaaag aatatagaga
     8821 gtctctagct attgagcagg agcgcaaagc agccacttcc gccaacgatg aactacatgt
     8881 tgcttagcaa tgtatgtttc atagtaatca cacattgatt actggttaca tatacagtta
     8941 aatttagccc tctgatatga gggcttttta tggcagtacg aaaactaacc acagggaaat
     9001 ggctttgcga atgttacccc gccggacgta gcggacgccg tgtgcgtaaa caattcgcca
     9061 ccaaaggcga agcactggcc ttcgagcgat acaccatggg ggaaatagaa gcaaagccct
     9121 ggctgggcga atcagtggat cgtcggacac tgaaagatat ggttgagcta tggttcaaat
     9181 tacatggcaa atctcttact gccggacagc atgtctacaa caagctgctg ttgatggttg
     9241 acgccttggg aaatcccctt gcaactgatc tcacctcaaa aatgtttgct cactatcgcg
     9301 ataaacgcct tactggtgaa atctacttca gtgaaaaatg gaagaaagga gcaagcccag
     9361 ttactgttaa cctggagcaa agccatctaa gcagcgtttt cagagaactt tcccgcctgg
     9421 gtgaatggac acttccaaac ccattagaga agatgcgcaa attcactatc gcagaaaagg
     9481 aaatggcatg gcttacacat gagcagatta tcgaattact gtctgactgc aaacgtcaga
     9541 acccaattct ggcactggtg gtaaaaatat gtctaagtac cggcgcacgt tggcgagaag
     9601 caatcaatct tacccgctca caggtcacca agtaccgaat cacctttgtg agaacgaagg
     9661 ggaagaaaaa cagaagcatc cctatcagta aagagcttta tgaagagatc atggcgctcg
     9721 atgggttcaa tttcttcaca gactgctatt ttcaattttt atccgtgatg gaaaaaacgt
     9781 ctatcgttct ccctcgcggt caactgacac acgttctgcg ccatacgttt gcggcgcact
     9841 tcatgatgtc gggtggaaac atcttggcct tacaaaaaat tctcggacac cacgatataa
     9901 aaatgactat gcgttatgcg catctggcac cggatcattt ggaaacggcg ctccgtttca
     9961 atccactggc aacgttacca aatggcgaca aagtggcggc agcggttggc attaccccgt
    10021 aataaccacc actgaccacc acattaagtt attgtttttc atataactta ttgtttttat
    10081 taatccattt agataagtgg gttttttgtt gcctgaaatt tatctactac cctgcaaccc
    10141 tctcaaccat cctcaaaatc tcctcgcgcg atagcggctt acggtcggtg acaaaatgca
    10201 gcgtcatccc ctcaataaac gcatcaagcg cgcgggcggt tccgggttca aaccattgtt
    10261 cgagcgtttg ctgactgcgc tgcatccagt tttgcattac cgtttttaat agcggttttc
    10321 ggctagccag cgcgtagagc tggtacatca gctccatgtt atccggcgtt gcaacctgtg
    10381 agctgtagat catatcggtg atagcctggc atgcgcccgg agcatcacta acatcgctaa
    10441 aaaatgcctg atattgccgg gacatgatct cagtaaaacg gctgaacgcc tccagcaaca
    10501 actcatcaat tcctgaaaaa tagtaagtca tcgatcccaa cggtaccccg gcaagggtag
    10561 caattttgcg gtgtgtaaca gcatgtattc cataaagttt caccgcctcc agcgtggcct
    10621 ggataatttt ttctcgccgt tgcggatcgt tagcgcgacg catgtcattt cctctctcta
    10681 caattgtgta caaatgtaca caatcttgct aatgttgtct tccctcttct tattttgacg
    10741 tggtctatga ccgtaaattc ttcacgtaat gcattgaaac gccgaacctg ggcgctgttt
    10801 atgttcttct ttttgccagg cctgttaatg gcgtcctggg caacccgtac gcctgctatc
    10861 cgcgatattc tctctgtctc gatcgctgaa atgggcggtg ttctctttgg tctgtcgatc
    10921 ggttcgatga gcggtattct ctgctcggcg tggttagtga aacgctttgg gacgcgtaat
    10981 gtcatccttg tgacgatgtc ctgcgcattg attgggatga tgatactaag cctggcactc
    11041 tggctgacat cgcccctgct cttcgcggtt ggtctcggcg tctttggggc aagttttggt
    11101 tctgcggaag tggcgataaa cgttgaaggt gctgccgttg agcgagaaat gaataagacg
    11161 gttttgccga tgatgcacgg tttttatagc ctgggcacgc tggcaggcgc tggtgtcggg
    11221 atggcactga cggcctttgg cgttccggca acggtgcaca ttttattggc ggcgctggta
    11281 ggcatcgcgc ctatttatat cgccattcag gcaatccctg acggtacggg caaaaatgct
    11341 gccgatggca cccagcatgg tgaaaaaggc gtaccttttt atcgggatat ccagttgctg
    11401 ctgattggtg ttgtggtgct ggcgatggcc tttgccgaag gttctgccaa cgactggtta
    11461 cccttattaa tggttgacgg tcacggtttt agccctactt ccggctcgct gatttatgcc
    11521 ggttttaccc tggggatgac tgttggacgc tttaccggcg gttggttcat cgaccgttac
    11581 agtcgcgttg ccgtggttcg ggccagtgca ctaatgggag cgttgggtat tggcctgatt
    11641 atttttgtcg atagcgcctg ggtcgctggg gtgtctgttg tactttgggg actgggtgcc
    11701 tcgctgggct tccctctgac catttctgcc gccagcgata ccggccccga tgcaccaacc
    11761 cgcgtcagcg tggtagctac gaccggttat ctggctttcc tcgtcgggcc gccgctgctg
    11821 ggctatctcg gcgaacatta tggattacgt agtgcaatga tggttgtact ggcgctggtt
    11881 attctcgcgg ctattgtcgc gaaagccgtc gccaaacccg ataccaaaac gcagacggcg
    11941 atggagaata gttgatgagc attaaattaa ttgcggtaga catggatggt actttcttaa
    12001 gcgatcaaaa aacctataac cgtgagcggt ttatggctca gtatcagcaa atgaaagcac
    12061 aaggcattcg ctttgtggtc gccagcggga atcaatatta tcagttgatc tctttcttcc
    12121 ctgaaattgc taatgaaatt gcctttgtgg ctgaaaacgg cggctgggta gtgagcgaag
    12181 gcaaagatgt ttttaatggc gagctgtcga aagatgcgtt tgctactgtc gtggaacatt
    12241 tgctgacgcg cccggaagtg gaaattattg cctgcggaaa aaatagcgcc tataccctca
    12301 aaaaatatga cgatgccatg aaaacggtgg cggaaatgta ttatcaccgt ctggaatacg
    12361 tcgataactt tgacaactta gaagatatct tctttaagtt tggcctgaat ctttctgatg
    12421 aactgattcc acaagtacaa aaagcattac atgaggccat cggcgatatt atggtgccgg
    12481 tccacaccgg caacggcagc atcgatctga ttatccccgg cgtacataaa gccaatggcc
    12541 ttcgccaact gcagaaatta tggggaatag acgacagcga agtggtggtc tttggcgatg
    12601 gcggtaacga tattgagatg ctgcgtcagg caggctttag ttttgcaatg gaaaatgccg
    12661 gcagcgcggt cgtcgcagca gcaaaatacc gggcaggctc caataaccgt gaaggcgtac
    12721 tggatgtgat cgataaagtt cttaaacacg aagcgccatt taaccaataa aaacggcagc
    12781 acgcccggca acacaatgcc tgaatgaagg ctgcataatt cgcggaaatt aacccgctgc
    12841 attatttcag gcgaaatgat tatgaaaaat tgtctactgt tgggcgcgct tttaatgggc
    12901 tttactggtg tggcgatggc gcaaagtgtc accgtcgatg tgccgagtgg atacaaagtg
    12961 gttgtggttc ctgattcagt cagtgttcca caagcggtca gcgtcgcgac tgtgccgcaa
    13021 accgtctatg tggctcctgc gccagctccg gcttaccgcc cgcatcctta tgttcgccat
    13081 cttgccagcg taggtgaagg gatggttatc gaacaccaga ttgacgacca tcaccattaa
    13141 tttgagaatg cctgatcgca caaagcaatc aggcattttt ttacccttcg tgcgaatttc
    13201 ccatctgttt atcttttaaa aagataacca tcagcaacag ccacaaaatg ccgttgacaa
    13261 ggttgaagag attaaacagt ccgttgcccc cgttcagcca ggcatgtttg ctgatttcaa
    13321 taccgacggt aaagatcagc atttgcagca tccccatcgc cgcagaaacc gtacctttac
    13381 tcatatcgct ggcaaacagg gttaatcgca ccagtcccgc attcgccaga ccaataccga
    13441 aagcataaat acttaacccg gcggtcatcc ataaatacgc gtgcgatgag ataaccgttg
    13501 ccgcagcagc gaccaacaga ccaatcataa tcggccagcc gcccataata atcagcgaac
    13561 gtacggtgcg gcgcgaggtc agacgcgcta acagcaagtt acccgcaatt aacgccccaa
    13621 aaataggcac ttgcagcaag ccatattcat agctgctcaa ctgctcaccg gtaataatga
    13681 taatcggcga ctgggcgatc cacgccaaca acggcaggct aacgaatccc agcgccagcg
    13741 cccccgccac aaagcgaccg ttcttcagca ccagcttata gtcacgaccg agttctttca
    13801 gcgacagttt ctcgcctata cgcgtggcgg tttcaggcat ggctcgttgc agaccgaaaa
    13861 aggagatcgc tgccaatgcg gcaaacaaga caaacatccc ctcccagggc agcacatgga
    13921 tccacgccgc gcccaccagc ggaccaagta gcggagcaat cagcgccacg ttcgccatca
    13981 gcgcggtgat cttgatacaa accgcctctt cgaaggattc ctgaattgcg gcgtatccca
    14041 cagcgccaat gaaacagagg cttatgccct gcaagaagcg caacagggtg aattgttcaa
    14101 tgttttgcgc cagtaatatt gccagacagg tgacgataaa ccacaccact cccgccagca
    14161 tcaccggacg gcggccaata cgatccgaca gcggccccag gagccattgt aaaaacatcc
    14221 cgcccgccag atacgcggtc atcgaagtag gaacccaatc aatgcccgcc tgatattgtt
    14281 ccaccaccgc caacataccg ggttgaatca tatcgttgcc gatataggtt gaaaattcgt
    14341 aaagcaccag acagagaggg aaaagtaacg cctgacgtcc aagcctggca ccggaagcta
    14401 atttattttg catgcaattt cttcgccaat aataatcgcg caaagtttaa taaaagcgca
    14461 gctaacgaga aagcaaattt tgtagctgaa accacggtta agcacattct tacattattg
    14521 cgagtatagc tacgctttct ttaagtttta tttaacctat gcccgttaca atcacccacc
    14581 gtaaacaggc cgcttgaggg aaataagacg atgccgcttt acccagttta acctgcactt
    14641 tattctcaac gacttgcctg tattggctcc cttttaatca ctttgcgtcg ggaagttatg
    14701 ctggaaaatt tgaatctctc tctattctct cttattaacg cgacgccaga ctctgcgccg
    14761 tggatgatct cgttggcgat ttttattgct aaagatttga ttaccgtggt gccgctgctg
    14821 gccgcggtac tttggttgtg ggggcttaca gcacaacggc aactggtgat aaaaatcgct
    14881 atcgcgctgg cggtcagcct gttggtgtcc tggacgatgg gacatctttt tccgcacgac
    14941 cgaccctttg tcgaaaatat cggctataac ttcctgcatc atgcggcgga tgactcattc
    15001 ccgagcgatc acggtacggt gattttcacc tttgcactgg catttttatg ctggcatcgc
    15061 ctgtggtccg gctcactttt aatggtgctg gccgtcgtca ttgcctggtc gcgcgtttat
    15121 cttggcgtcc actggccgct ggatatgctc ggtggattgc tggcaggtat gattggctgc
    15181 cttagcgccc agattatctg gcaagcgatg gggcataaac tctatcaacg tctgcaatcg
    15241 tggtatcgct tctgttttgc attaccgatc cgcaaaggct gggtgcgtga ctgatctctg
    15301 ctaaaaagtg tagtattgag cggctcgctt caataactat tcagagggat tatggaaaca
    15361 cgtcgcgaag agcgtatcgg gcagctgctg caagaattaa aacgcagcga taagttacat
    15421 cttaaagacg ccgccgccct gcttggggtt tcggagatga cgattcgtcg cgatctgaac
    15481 aaccacagtg cgcccgtcgt tttgctcggc ggctatattg ttctggaacc gcgcagcgcc
    15541 agccattacc tgctaagcga tcaaaaatcc cgcctggtgg aagaaaaacg ccgggcggca
    15601 aaactggctg cgacgctggt agaacccgat cagaccctct tttttgactg tggcaccacc
    15661 acaccgtgga ttattgaagc gattgataat gaaatccctt tcaccgccgt ttgttattcg
    15721 ctaaatacct ttctggcact gaaagagaaa cctcattgcc gcgcgtttct ttgcggtggt
    15781 gaatttcacg ccagcaacgc cattttcaaa cccatcgatt ttcagcaaac gctgaataat
    15841 ttttgcccgg atatcgcttt ttattccgcg gcgggggtgc atgtcagtaa gggcgctacc
    15901 tgttttaatc ttgaagagtt gccggtaaaa cactgggcca tgtcgatggc gcaaaagcat
    15961 gtgctggttg tcgaccacag taaatttggc aaggtgcgtc cggcacgcat gggtgacctg
    16021 aaacgctttg atattgtagt gagcgattgt tgcccggaag atgagtatgt gaagtacgcg
    16081 cagacgcagc gtattaagtt gatgtattaa tgacgtataa ccggatgacg tttcgcgcca
    16141 tccggttatc acaaaattaa gagaaccagc tgccgaacca ctgatggaat ttcatcatca
    16201 cgaaatccca catccgacca aagaatccgc cctcttccac attttccatc acgatcagcg
    16261 gacgctgctc aatggattta ccgttaagct ggaaatcaat ggtcccgaca acctgacctt
    16321 ttttcagcgg tgcggtaagc tgcggttccg ttaacgtgta gctcgctttc aggtttttca
    16381 gctgcccacg cggtatggtc actgagcccg cttcgcctgc cccgagattc acttcgctct
    16441 tatcaccaaa ccagacgcgc tgagtcacaa aggtggcatc aggtttaatt ggcgtcacgg
    16501 tttcaaagaa gcggaaaccc caggtcaata atttctcaga ctcattaaaa cggatacggt
    16561 cagttttcgc ccccagcact acggagatta aacgcatatc accctgggta gccgaagcaa
    16621 ccagattata tcccgcgcct gcagtggttc ctgtcttcat gccatcaaca ttcagattgc
    16681 tgctccacag cagacggtta cggttaggct gacgaatttt gttgaaggtg aactctttct
    16741 ctttatgaat ggcatactct tccggcacat cgtggattaa tgctttaccc agcaatgcca
    16801 tatcgcgcgc ggtactgaac tgccccggcg catccagacc gtgcaccgtc tggaaggtag
    16861 tgttggtcag acccagtttt ttggcataac cattcatcaa accaataaat gactcctggc
    16921 tcccggcaac gtaatcggcc agcgcaatac aggcgtcatt accggactgg ataatcacac
    16981 ctttgttcaa gtctgccacc gaaacctgat cgcccggttt gaggaacatt accgatgaac
    17041 cacgcagtgc cggatttccc gtcgcccagg catctttacc gaccgtcacc atatcggtga
    17101 gtttaatctt atcggcctta agcgcctgcc caaccacata gctggtcatg attttagtca
    17161 ggctcgcggg atccagtttc tcatccgcat tgccttctgc cagcacttta ccgctggcgt
    17221 aatccattaa aatccatgca cgcgcatcca cgctcggcgc ttcaacggtt tgttcggccg
    17281 cgaatgccgt tggggcaaaa aggaataaaa atgcagaacc cgctgcaaga ccacgaagga
    17341 gagaggagta ttgcgtcata aatgccaccc gagtatccat tcaaaaaaaa tacgttatat
    17401 cgccgtatga taagttcggt gattaataac gcacacacaa acttaaagaa accgtaagtt
    17461 ggtaaagttt ttaaagttta tgcaatatcc tgccgcttcg ctgcttctgt tgtcattttt
    17521 ttgccagctg ttgcttaaaa gttaacttta cttcaccatc aaagtcctgt tcagcctgtg
    17581 gctgcctgtc ggaaaagggg tgagtatgat tacgctgtgg ggtcggaata attcaaccaa
    17641 cgtaaaaaaa gtattgctga cgctcgaaga actggaacta ccttatgagc aaattctcgc
    17701 gggccgtgag tttgggataa atcacgatgc tgattttctg gcgatgaacc ctaacgggct
    17761 ggtgccattg ttgcgtgacg acgaaagtga tctcattctt tgggaatcaa acgccattgt
    17821 ccgctatctg gcggcacagt acgggcaaaa acgcctgtgg atcgactcac cggcacgtcg
    17881 tgcggaagca gaaaaatgga tggactgggc aaaccagacg ctcagtaatg cccatcgcgg
    17941 gatcctgatg ggattagtca gaacaccacc ggaagagcgc gatcaggccg ccattgatgc
    18001 cagttgtaaa gagtgcgacg ccctgtttgc cctgctcgat gcggaactgg caaaagtaaa
    18061 atggttctcc ggcgacgagt ttggtgtggg cgatatcgct atcgcaccgt tcatctacaa
    18121 tttgtttaat gttggcctga cctggacacc gcatccaaat ctgcaacgct ggtatcagca
    18181 actcactgaa cgccccgcag tgcgcaaagt ggtgatgatt cccgttagct aattgcgtgg
    18241 gctaacttta agtaattccc cactggactc gtcggtgaga acgtataaat aaccgtcggg
    18301 tccagtgcga acatcacgaa ttcgctgccc tctgtccgtt aaaatacggc catcttctgt
    18361 cactttgtcg ccgttgacgc tcatcacaat gacatcttta tctttcagcg cgccaataaa
    18421 taatttttgc tgccactggg ggaatttatc gctgttatag aaggccatgc cgctcacggc
    18481 gggcgaatct ttccagtaaa aaacaggttg ctcggtcccg gcgacgatct tccctttcgc
    18541 ttccggtatc ttaaagcccg aatagttgat tccccaggtt gccagcggcc agccgtagtt
    18601 tttgcctttt tgcgggatat taatttcatc accaccgcgc gggccatgtt cattcagcca
    18661 tagtgcttta ctccacggat tcatcgccat tccttgtgga ttacgaatgc cataagacca
    18721 gatctcggcg cgtgcaccgg attcctttat aaaaggatta tcatccggga tttcgccctg
    18781 gtcggtcaga cgcaccagtt tgccctgtaa tttatccaga tcctgcgccg tcgggcgctg
    18841 attgttttcg cccagagcaa tcaaaagata acctttaccg tcgaatacca tccgcccgcc
    18901 aaaatggttg ccggtagaca gttttggcat ctgacgaaag acggtgcgga agtcggtcac
    18961 ttttgagaga tcatcactta agcggccata acccacagca gttccggctt tgccatcatc
    19021 gcctacttcg gaataactta accagatgcg gcgagactga gcaaaatcag gcgctaaaac
    19081 cacgtccagc aggccgccct gcccgtgcgc ccaaacgtcc ggcactccgg aaagcggcgc
    19141 agataatcct tttcctgctt gccagtgacg caactcgccg ccgcgcagag tgattaacat
    19201 accgtgattg tcgggtaaaa aggccagcgc ccagggatgg tcgagtttgt cttgcagtac
    19261 ttcgacattt accgttgcag gagccgccca gagagcggaa gaaagacaaa taaggggcac
    19321 aaggaaaaag aattgtcgat gcataacgcc tccggattga ctctggctta aagcgtagtc
    19381 agtggaggag agaacaaatt catttttaca aaaacttaaa catgaagggg gagacgcttt
    19441 ctccccctta gttttcaggc cttctcaagc atggcgtgct tctgcaggct ctggatactc
    19501 agcgttaagc tcatcagaca attttcaagc ttatcggcgt tgacggtaat aacagtcggg
    19561 caatcatggt gcccactcat caaacatact gcggctgtcg ctaatgcttc ttcagcatga
    19621 tgaagagcac tccactcttc ctgatccaga tgaagattca accgcagcga tttatcgtgc
    19681 agttcgcgat tcagtttaaa aaagttatct cgtagatgat tgctttcgct gacggacatg
    19741 tatccttttg ccttcctcag ttgcacgtat gcggcgaggt caacgcgtgc gtcgatcaac
    19801 cggttcagca gatcgattcg ctgtctgtca acgaacatac ttcgatcctc ctctttccag
    19861 ccttgttgca attaaatagt atggctattt tttgagcaaa atgctgtcca ggatcaattc
    19921 ttcacgccga attaacaaaa tttacatttc cttcgcctcc gccagcgtat gagattgcga
    19981 tacaaatttt atccagaact ctgtagaatc cctgccctga cctttcctgt aactgaatat
    20041 tttttaagct atgagcaaag taactcccca gccgaaaatc ggctttgttt cccttggctg
    20101 tccgaaaaac cttgtcgatt cagagcgtat tctcaccgaa ctacgcactg aaggttatga
    20161 cgtggtaccg agctatgacg atgcggacat ggtgatcgtc aacacctgcg gctttattga
    20221 cagcgcggta caagaatcac tggaagccat tggtgaagcg ttgaatgaaa acggcaaggt
    20281 aattgtgacc ggttgtctgg gggcaaaaga agatcagatc cgcgaagtcc acccgaaagt
    20341 gctggaaatc accgggcctc atagctatga gcaggttctg gagcacgttc atcactacgt
    20401 gccaaaaccg aaacacaacc cattcctgag cctggtgcca gaacaaggcg tgaaactgac
    20461 gccgcgtcat tatgcctatc tgaaaatttc tgaaggctgt aatcaccgct gcaccttctg
    20521 cattattccg tctatgcgcg gcgacctggt gagccgtccg attggcgaag tgttaagtga
    20581 agcgaaacgt ctggttgatg cgggcgttaa agagattctg gtgatctcgc aggatacttc
    20641 cgcctatggc gttgatgtta aacatcgtac tggcttccac aacggcgagc cggtaaaaac
    20701 cagcatggtc agcctgtgcg aacagttatc gaaactgggg atctggacac gtctgcacta
    20761 cgtttaccct tatccgcatg tggacgacgt catcccactg atggcagaag gcaaaatcct
    20821 gccgtatctg gacattccgt tgcagcacgc cagcccgcgc attctcaaac tgatgaagcg
    20881 tccgggttct gtagatcgcc aactggcgcg catcaaacag tggcgcgaaa tctgcccgga
    20941 actgacccta cgctcaacct ttattgtcgg tttccctggc gagacggaag aagatttcca
    21001 gatgctactc gacttcctga aagaagcacg tctggatcgc gttggctgct ttaaatacag
    21061 cccggttgaa ggtgcagacg ccaatgccct gcctgaccag gttccggaag aagtgaaaga
    21121 agaacgctgg aaccgtttca tgcagttgca gcagcagatt tccgccgagc gcctgcaaga
    21181 gaaagtgggc cgtgaaattc tggtgattat cgacgaagtg gacgaagaag gtgcgattgg
    21241 tcgcagcatg gcagatgcac cggaaatcga cggcgcggtt tatctcaatg gtgaaaccaa
    21301 cgttaagccg ggtgatatcc tgcgtgtgaa agtcgagcac gccgatgagt acgatttgtg
    21361 gggtagccgg gtttaattaa tcttaaggca gatctaacaa ggatattgtt cttcgatctg
    21421 cctctgctac ccttcccgat gtcctaccct tacgcacaaa atcccctgac gcataaatcg
    21481 agaaaaatga atcgtactcg aggcaactct cactttttca caccaaatta aagttttgat
    21541 cgcaattact tgaaataagc gtaatggtta ctatagtaaa cattaccaca aggatggatg
    21601 tatgggtgtg tataaggcaa gacgattcag ccaaagcacg aaaaaacttg gtattcacga
    21661 taaagttctc atggctgccg ctgaagaagt gatgcagggc atatgggagg ctgatttagg
    21721 tagcggtgtc atcaaaaaac gtttacccct ccaacaagga aagagtggtg gagccagaac
    21781 aattatcttt tttaaatcag caaatcatgt gtttttttat gatggttggt ccaagagtgg
    21841 tctaagtagt aaaggaacca aagaaatcga agatgatgaa ctggcggcct acaaaaaaat
    21901 ggcaaatgca tttctggcct ttagcaataa gcaaatagag gatttgatcg aaactggctt
    21961 tttgattgag gtgaaaaatg agcgataaat tacaaatgat gctggaagat gcaaaggaac
    22021 tgaatgcact gggcctgatg tctgatagtg aagttgatgc cattgccgtc atggtcaaag
    22081 ctcgtgaagt cagcgcccgt atagccaaag tcaaatcaat gacgggtgaa gagatcaaag
    22141 ccatccgcac ccgatacggc atgtcacaat ccgtgctggc acatacaatg ggaatgtcaa
    22201 aagaaagtgt ctcgaaatgg gaacgtaatg aaataaaacc gagcggcccg gcattacgta
    22261 ttttgaatac attggcaata aaagggccgg aagtttttgc aaagtaaaat gtttgcaaat
    22321 gatttaccac attcattagt accccttgat taaggggtac taacactatt ctaattctac
    22381 tgccagctaa tctgtgccct gccgtttttc ttactcttat acagccgctc atccgccagc
    22441 attttcaagc gttcgacggt aggacattca tttgaatgcg ctacaccgat actggtactt
    22501 aaattaatgc ttcccacctg gaaatgaacg atttctttta gaatcgatag caactcttcc
    22561 agcgtgccgc cagtataaat caccgcaaat tcgtcaccgc cgaagcggta gactttacct
    22621 ttatctaccg ggatctgtga tttaaggatt ttcaccactt tcatcaacac ttcatcgccc
    22681 agcaaatgac cgaaggtgtc gttaatgttt ttgaatttat cgacgtcaaa caggcacaaa
    22741 tagccgcctt tttccggcag ggcttttaaa tcttcatcaa aggattttct gcccattgct
    22801 ttggtcagat cgtccaggaa tgccgagtta tacatactgt agagtttttt gacatcggca
    22861 gccgaaaaga aaagcccgcc atccaggacg cgttcaaaat ggttattaat aatggcttct
    22921 ttctccacaa taccacgatt aatcactctg cgtaccagat agaggcaact ggcacccgat
    22981 atcactgcca ccaatgcggc aaagaaaata atcaatgtac atacctgaaa ataaacgtct
    23041 tttttatacg caaatacgta caatccggtc ggcaaatagg agaagtgctc cattgcttcc
    23101 gaaacggtga agatggcgtt tttagcgtta tattcatcac cggtcaccgg tttaccgttc
    23161 ttaaacaggg agaacatcag gttctcgcta tccatcgcca gcgattttga cagtaaagaa
    23221 aaacgttcca gaccaagcaa aaatatcaga ctacgattgt gagttaccgg atagaggtaa
    23281 tagacgaagg ttttaccatc aaaagagata aaccctgtat ttttgacatg tcgatacttc
    23341 acaacctgca taatatctgc acaataattt ttctcgaact cctttacctg aatacattcg
    23401 tcactggaaa tcagataagg accgacatcg tacaaataag agggtgaaag cgagtcggcg
    23461 taagctgtgc gtaagccaac caacagctgt tcctccgtag gatttagcgt gttgatcaga
    23521 tcaattgcca cactacgccg atattcagca atatttgcca ccgcaaaagc agtatcaata
    23581 acggactgtt tcaggccata cacccgttcc tttaccattt gagtgtagat cccgcaggca
    23641 actgctgaaa tcatgataaa aatcagcaga ctgactgtaa gtacgaactt attgattctg
    23701 gacatacgta aactactctt ttactaattt tccactttta tcccaggcgg agaacggcat
    23761 gggtttctgg tacagatacc cctgagcctg aacacatcct aatttgatta attcgcgcgc
    23821 aacgtcttcg ctctctacgc cttccgcaat caccgggatc cggttatagc gtgccagatc
    23881 gaaaataatg cgcacaattt ttcccgcagt accgaaaata tcgccggtaa attgtgagtc
    23941 cacttttatg ctatctggat taatttcata aaaacgtttc aggtttgaca aaccggtgcc
    24001 aaagtcatca atcgatatcc gtaccccttg tttacgcagt tgttcaatat tgagataaaa
    24061 atgttcatta attcgctcaa tcacggtttc agtgatctca acacagaggc tgttcgcctt
    24121 caggccattt tcttccatga tggtggtaaa acgctcatga aagtgtggtt cgtttaactg
    24181 ccagggcgaa acattaatat gcagtaagaa accgtccttc aggaccgcac gctgactaaa
    24241 atgtctgaat tcacccatcg cggttttaat aatctgataa cccagctcat tgataaaccc
    24301 gatatcttca gcaatggtaa tgaactttag cggtgaaatg atcccccgct ccgcagacac
    24361 ccaacggcac aacgcctccg cgcccagaat ggcgcgggtg ttaatatcaa cgatcggttg
    24421 atagacgagg aatagttcgc caatttccat tgcatggcga atattacgcg caatccagat
    24481 attctcttct atttcgttga gtttcgcatc atcacagaaa ataaactctg agaacatatg
    24541 gttgcggata ctggaaatcg ccagtttcag cttttctgcg taactccagg cgttttcccc
    24601 ctgcaaaggt tcacaaatag cagacttatg gatgcgcaga ttgcggtagc caaaactgct
    24661 gtcaaaatcg tttaccgtcg ctatcttacg ggtaaacgtc tgtacatttt cccggcacag
    24721 gagtaaatag agatcggcat taaatgtcac gatatcgcag cattgcgcat atttctcggc
    24781 aattcgctga cacaatttcc tgacgatttt attgcgttca tcaacaccaa acaccgcttc
    24841 cacagcttcc agaccacaca gtttgatgat ccccacagcc agatactgat tattgttgga
    24901 ctcaataatc gccatatttt taataaaacc gctttcctga tcgtaagaga tcagcgagag
    24961 caatttattt gcccgttcaa tttcagcatc tttcatttcc gcgatcgaat ttttgatact
    25021 gataatctct ttcgcatcgc cttcacgaat cttcagggcc tcgatttgat ccgtagagtc
    25081 aggcaaaaac gccagcgtat taaccagttc ggtcatttca gaaaattgcc gacggaaaac
    25141 tcgagtggtc attaaataaa ccaccagcaa tacgataata atgaaagcaa acggcagata
    25201 aaaaagttta tctgatgcgt tcaataaatt accaccagga taataaaaat agatttcgaa
    25261 taatgcgttg tttggcaccg ctgatgtttt ttcaatatat tccgtatcga cagaatcaat
    25321 aatattataa ttaccttcgc tattataaat aatcaatttt tcacgagcga gttgattctt
    25381 agcaatgatc tcatgacctt gctttaaaaa tagaacttca tcattagcgc tgatttgatc
    25441 aagatactcg ttcagatatc gccagtttaa atcgacatga attttatcca ccgctaacaa
    25501 atcgtgatct ttgccgttga tgtgtagcgt aaaagagata cattttttac ccggacgatc
    25561 aaagcaattg tatgccggat tccagctgtt gttagagtca tctgaagcca ccgaccacgg
    25621 tcgtttcgat gggttaaaat cggcaaaaat aacccgccct gactcgtcga caagcggtcc
    25681 atttacttgt tcctgatgat aaacaacgat tttatcattc gccctccgcg aaaagagata
    25741 atatttatta tcatcaagta ccagtcccac cgagtctaaa aatggcatca tttccatttt
    25801 cagaattacg gcgcgttgaa tctcctctgt attttttaat aaatacagtg agtcctttaa
    25861 tgtcagggcc gaacgttcaa tatctttaaa gaaatagcca acgtttttct gaataagttc
    25921 aaagcggcta tcggcacgtt ttaccgcgcg ttccgatacc agttgatagt taatgatgaa
    25981 aaaaagacca ataaatgaca gtgctgccaa taaaaataaa attatcagcc ttatctttat
    26041 cttttcgtat aaactcagca tgttaataca tttaacaaaa taactgtctg aacgctgtgc
    26101 cgctgcaaaa tagtcccttg ctgcggcttt ttaaccaaat tacccgattc tacaaaatca
    26161 gcagaaagtt acaacacttg cttagggcaa taatttcctg tgaggtgatt accctttcaa
    26221 gcaatattca aacgtaacta tcctttaatt ttcggatcca gcgcatcgcg taaaccatcg
    26281 cccaacaaat tgaacgccag tacggtcaga aaaatagcca gggccggaaa aacagcgaca
    26341 tgcggcgcga taaccatatc cgctcgtgcc tcattgagca ttgctcccca ctctggtgtc
    26401 ggcggctgcg caccgaggcc gagaaatgac aggctggcgg cagagataat cgaggtacca
    26461 atgcgcatgg tgaaaaacac cacgatagaa gagacggtcc caggcaggat atgacgcaat
    26521 aaaatggtca tatcgctggc accaatactg cgtgctgact caataaaggt ttgctgtttc
    26581 aacaccagcg tgttgccgcg caccagtcgg gcaaacgcgg ggatggaaaa aatggcgact
    26641 gcgataatca cgttagcaat gccgcttccc aacaccgcaa caacagcgat cgccagtaaa
    26701 atacccggga aggcaaacag cacatcgcaa atgcgcatga tcagccgatc ccaccagcct
    26761 tcataatatc cagccagcaa gcccagcaac gtcccgatcg ccgcaccgat aaacacggca
    26821 aacacgcccg ccgccagcga gatttgcgca ccaaccagga cacggctgaa aatgtcacgc
    26881 cccagtgaat cgacgccaaa ccagtgctgc aaagaaggtc cgttattcag attgtcataa
    26941 tcaaaataat tttcggcgtc atagggagca atccagcgtg caaaaatggc caccacaatc
    27001 aataaaataa cgaacaatgc ggcggtcatc gccatatgct gacggcgaaa tcgtcgccag
    27061 aattcatgcc acggtgtacg tacctggtca ggtttgacca gtggcatggc gtttaacacc
    27121 gcctgacgtc gccagttaaa tagtcgcatc cttacttgta cctgatagcc gggttaatgg
    27181 cggcgtaaag cacatccacc actaagttga taagaataaa ttccagcgag aaaagcagaa
    27241 tttccgcctg aatcaccggg taatcgcgca tttctacgga gtcaacgagt aagcgtccaa
    27301 gtccgggcca gttgaaaact ttctccacca cgatggaacc accgagcaaa aagccaaact
    27361 gtaagcccat catggtcact accgggatca tcgcgttgcg tagcccgtgc ttgaggacaa
    27421 cccaggtttc gctcacccct ttcgccctcg cggtacgcat ataatcttcg cttaaaacgt
    27481 cgacaaacga cgcgcgggta aagcgcgcca tcacggctgc cactgccgcg ccgagcgtca
    27541 gggtgggtaa aatgtagtgc tgccaactgt ctgctcccac ggtaggcagc cagcccagtt
    27601 caacggagaa tacctgaatt aaaagcatcc ccagagcaaa tgccggaaac gagatccccg
    27661 acaccgcaat ggtcatactc aatcgatccg gccaacgatt acgccagacg gcggcgataa
    27721 ttcccgccgc cataccaaat atcaccgccc agaccatact ggttatggtc agccacagcg
    27781 ttggcataaa gcggctggca atctcatcgc caaccggacg acgcgacacc atcgccaggc
    27841 caaaatcccc ctgcacagca ttgctgatat agtgccagaa ctggtgatac agcggctgat
    27901 ccaaccccag ctgctgacgc accagttcta taacctgcgc atcagcttcg ggcccggcaa
    27961 tcaatcgcgc cggatcgccg ggcagcatat ggacaaataa aaacaccagc accgagacga
    28021 taaacagcgt cggaatcaac cccagcaagc gtttgataac gtaattaagc attccactcc
    28081 ctgcgttgct tattgcaaat ccgcgtcttc aaagctgaag ccggtgtctg gcatgatcca
    28141 aaaaccggtc aggtttttac tgtgtgccga caccagtttt tctaccacca gcgggatcca
    28201 cggcgactct tgccagatga tatcctgcgc cgccttatat aaacgggtct tttccgccgg
    28261 atcattagtt ttcaatgcct gagccaggaa gtcatccacc tgtttattgc tgtaaaacgc
    28321 ggtattaaac agcgtcggtg gccagttctg cgaggcaaac agcggcgata gagcccagtc
    28381 tgcttcgccg gttgaagccg accagccagt gtagaacatc cgcacgccgc tctctttttg
    28441 ccctttacct tcaacttctg ccgcccgctg tccggcatcc atcgcagtca cctgggcttt
    28501 aatcccgacc tgcgctaact gctgctgggt aaattgcagc actttctgcg cagtgctgtg
    28561 gttatgtgac gaccacagcg tggtactgaa accgttggga tatcccgcct ctttcagtaa
    28621 ttcgcgcgct ttcgccggat cgtaaggcca cggtttataa ctttgcgcgt aggcgatact
    28681 cggcggtacc acaccagtag ctggcgttgc ataacccgcg aaggccactt tcaccagcgc
    28741 cgggcggtta atggcgtaat tcagcgcctc acggaccttc gggttatcga acggcttttg
    28801 cgtcacgttc atactgatat aacgctgcat aattgacgga ctggccatca actcgatatt
    28861 tttgtttttc tccagcagtg cggcctgctc gtagggaatg gggaaagcaa actgcgcttc
    28921 accggtttgc agcatggccg cgcgggtgtt gttatccgcc accggacgcc aggttatgct
    28981 gtccagtttg ggcaatcctg gctgccagta acccgcgaat tttttcacct tcacaaaatc
    29041 ggtctgattc caggtatcca gttcatacgg cccggttccc accggatgaa aaccaatctc
    29101 cttgccatat ttttccagcg ctgccggtga aatcatcgcg gtcgccggat gggcaagaat
    29161 attaataaac gctgagaacg gctgtttgag ggtaatcttt accgttgtcg gatcgatcgc
    29221 ttccgttttg gcaatattct tatacaggtt gtagcgttta agatgattcg ccggatcgct
    29281 ggcccggtcc agattcgctt ttaccgccgc tgcgttgaag tcggttccat cctggaattt
    29341 aattccttcc cgcagtttca cggtgtaagt aaggccgtca tcggaaacgg tataactctc
    29401 cgccagcacg tttttcagtt tcatctcttt atcgagaccg aacagcccct ggtaaaacga
    29461 tttcgctacg gcctgagata acgtgtcatt cgcgtcatat ggatcgagcg tggtgaagtt
    29521 cgatcctacc gccaccacca catctttggc agcgaatgca caagatgcca tcaacgctgt
    29581 cgcaatgccc agcgccacta acccactacg gtgtacagct cttgccattt tattctccgc
    29641 ctgaatgtta tctacgcatg aatgcgtatt ctgattgtgg ttgtgcgacg taatgccccg
    29701 gcccgacgca ttgcaacgag acggctacaa cctcttcacc acgcagatga atattgctgg
    29761 gaagatcgtc cgacagcagt acacgctgcg gtcgttgtcg ggacggttca gcgaccggaa
    29821 ctgccgccag taatttacgc gtataaggat gctgcggatt ttcaaagacc gcgcgccgtg
    29881 gaccaatttc aacaatttgt ccgagataca tcaccgccac acgatgacta atccgctcta
    29941 ccacggccat atcgtgggag ataaacagat acgcaatgcc gaaatcacgc tggagatcga
    30001 gcaacaagtt gataatctgc ccgcgaatag atacatccag cgccgagacg gcttcgtcgg
    30061 caatgatcac ttttggattc aatgccaacg cgcgagcaat gcagatgcgc tggcgctgac
    30121 cgccggaaaa ctcatgcggg taacgccagg catgttccgg taacaggccc acgcgctcca
    30181 gcaaccacgc aacgcgtgca gccgcttctt tacctggcaa taaaccgtgt acgcgcagcg
    30241 gttcgataat cgaatcaccg atggtctgac gtgggtccag cgaagcgtaa gggtcctgaa
    30301 aaataaactg aatatcgcgg cgcaatgcct gaagtttacc ggatgacaag gtatcgattc
    30361 gctgaccgtt aaagataatt tcgccgccct gcgattcgac caggcgcagc aacgcccgcc
    30421 cggtagtgga tttaccgctg ccagactcgc ccaccagcga tagcgtttcg ccaggccaga
    30481 gatcaaaact gactttctca acggcatgca cttcccgcgt tacgcgattc aacaaaccgc
    30541 tgcgcaaagg gaaacgggtg accagattac gcacccgtaa aacaggttcg ccatccacca
    30601 ccgttttctg ctcgatgggt ggttcctgtt tcgctggatg ttcaagcgat atcaatggga
    30661 aacgtcgggg ataatctaac cctttcatcg caccaagttg cggaacagca gctaacagcg
    30721 cacgggtgta aggatgttgc ggtgcatgaa aaatctgttc gacgctaccc gtttccaccg
    30781 cctcgccctg atacatcacc agtacccgat cggcaatctc tgccaccacg cccatatcgt
    30841 gagtgataaa gataacgccc atcgacatct ctttttgcaa tactttgatt aattgcagga
    30901 tctgcgcctg aatagtgaca tccagcgcgg tggttggctc atcggcaatc agcaccgccg
    30961 ggcggcatga cagcgccatc gcaatcatca ctcgctggcg catcccgcca gagagttgat
    31021 gcggataacg tgaaagaatg gtttgtgcct ccggaatgcg tacctgatcc agcatccgct
    31081 tcgcctcgac catcgcttct tcacgactgg cgttctgatg cagacgaatt gattcggcaa
    31141 tctgttcacc cacagtaaat accgggttca gcgatgtcat cggttcctga aatatcatcg
    31201 ccatatccgc accgcgcaca tggcgcattt gtgcagcgct ctgctcgcta agttcaatca
    31261 cttcgcgact gcgccgccgc aacagcattt tatcgcactg tactaaaccg cccgcctgtt
    31321 ccaacagacg catcaatgcc agcgcagtca ctgacttacc ggagccggat tcgccaacaa
    31381 ttgccagcgt ctcaccgcgt tgcaggctaa aagagagatt gcggaccgca gctattttct
    31441 gctggtcctg cataaaggca atattcagat tttcaaccgc cagcacatca ccggcatcaa
    31501 gttcatcact gtgtggcaac ggtgtcccct ttttcacggt agataccggt ggttggcgta
    31561 tcgcctgcgt agccccaggc gcgatacatt ccttcggtgt taaacggtag cgcgacattc
    31621 ccttcatggt cgatagcgat taagccaccg ctaccgccaa gcgcagggag tttttccatt
    31681 actacccgct cgcaggcttc cgcgagactt aatccgccgt aatccattaa cgcggcgatg
    31741 tcatatgccg ccagcgcgcg gatgaagact tcgcccgtgc cggtacaaga aactgccaca
    31801 ctggcgttat tggcgtagca tccggcaccc actaagggac tatcgccaac tcgtccgggt
    31861 aatttattgg tcattccgcc cgtggacgtg gctgccgcca gattgccgtc taaatccaac
    31921 gccacggccc ccacggtgcc cattttctgt ttttcatcca gtggcgcacc gctatggtcg
    31981 aggactgttg ccccttcctc gcgcgctgcc agtagttgtt cataacgcaa aggcgtggag
    32041 aaaatctccg gtgagacgcg ctccatgcca tgagcaaacg caaaattttc tgccccttcg
    32101 ccaatcatca tcacatgcgg gctttgctcc atcaccagtc gggcggcaag aaccggatta
    32161 cgcagatgac taacgcccgc caccgcaccg gctttcaggg tgttaccatc catcacacag
    32221 gcgtccagtt catgggtttc atcacgcgta aagacagcgc caattccggc gttaaacagt
    32281 ggacactctt ccagcagacg caccgcttcc gtcaccacat tcagcgcact ttcgcccgct
    32341 tccagcattt tctgcccggt ttcaacaatg gcagacagcg cctcgatgta gcgtaattcc
    32401 tgttgcagac tcatctgcgc gcggctaatt gcacctgcgc caccatgaat tgcaatgact
    32461 gctttgccca tagtattcgt ccattaaggg tggctcgcca cttttgctat aaatatcaga
    32521 atttttatga attactcatt caatttttga atatagaaag atggatatgg catgtaaagg
    32581 caggagccaa cgctacgccc gaggtggcat acagtctgtg gcgtttttct gacataatag
    32641 gcaaattcga ttttgcctcc gcaggagtgt tttcatggaa tttaccaccg gattgatgtc
    32701 gctcgacacc gcgcttaatg agatgctttc tcgcgttacc ccactgaccg cccaggaaac
    32761 gctgccactg gttcagtgtt ttggtcgtat tctggcgagc gatgtcgttt cgccactgga
    32821 tgtcccgggg tttgataact ccgctatgga cggctacgcg gtgcgtttag ccgatattgc
    32881 ctccgggcaa ccgctgcccg ttgccggtaa atcctttgcc ggtcagccgt accatggtga
    32941 atggcctgcg ggtacctgca ttcgtattat gaccggtgcg ccggtgccgg aaggctgcga
    33001 agcggtggtg atgcaggagc agactgaaca aacggacaat ggcgtgcgtt ttactgctga
    33061 agtgcgtagc gggcaaaata ttcgccgtcg cggtgaagat atctctgcag gtgcggttgt
    33121 tttcccggcg gggactcgcc tgactaccgc agagctgcca gtaattgctt cactggggat
    33181 tgccgaagtt ccggtgattc gtaaagtgcg tgtagcgctg ttttctaccg gtgatgaact
    33241 ccagttgcca ggccagccgc tgggcgacgg ccaaatctac gataccaacc gtctcgccgt
    33301 acacctgatg ttagaacagt tgggatgcga ggtaatcaac ttagggatta tccgcgacga
    33361 tccccatgcc ctgcgcgccg catttattga agccgacagc caggcggatg tggtgatcag
    33421 ttccggcggt gtttcagtgg gtgaagcgga ttacaccaaa accattcttg aagagctggg
    33481 ggagatcgcc ttctggaagc tggcgattaa accaggtaaa ccgttcgcgt tcggtaaact
    33541 cagcaatagc tggttctgcg gcctgccggg caacccggtt tcagcaacgc tgaccttcta
    33601 tcaactggta cagcctttgc tggcaaaact aagcggcaat accgccagcg gcctgcccgc
    33661 gcgccagcgt gtgcgcacgg catcgcctct gaagaaatcg ccaggacgcc ttgatttcca
    33721 gcgcggcgtg ctgcaacgca acgccgatgg cgaactggaa gtgacgacca ccggacatca
    33781 gggttcacat atatttagct cctttagcct cggcaactgc tttatcgtgc tggaacgcga
    33841 tcgcggcaat gtggaagtgg gcgaatgggt ggaagtagaa ccgtttaacg cgttgttcgg
    33901 aggcctgtaa tggcggaact cagcgatcag gagatgctgc gctacaaccg gcaaatcatt
    33961 ctgcgcggtt ttgattttga cggtcaggag gcgctaaaag attctcgtgt gctgatcgtc
    34021 ggcctcggtg gactcggctg cgcagcttcg cagtatctgg caagcgccgg tgtcggcaac
    34081 ctgacgctgc tcgacttcga cacggtttcg ctctcgaatc tgcaacgcca gacgctgcac
    34141 agcgatgcca cggtcgggca accgaaggtg aaatccgccc gtgacgccct gacgcggatc
    34201 aacccacata tcgcgattac gccagtcaat gcactgcttg atgacgctga acttgctgcg
    34261 atgattgcaa aacacgatct ggtgctcgac tgtacggata acgttgcagt acgtaatcaa
    34321 ctgaacgcag gctgttttgc cgcgaaggtg ccgctggttt ccggcgcggc aattcgtatg
    34381 gaagggcaaa tcacggtctt cacttatcag gacggcgaac cgtgctatcg ctgccttagc
    34441 cgtttgtttg gcgagaacgc gttaacctgc gtagaagcag gcgtgatggc accgttaatc
    34501 ggcgtaattg gttcgttgca ggcaatggaa gcgatcaaac tgctggcagg ttatggcaaa
    34561 ccggccagcg gaaaaatcgt gatgtacgat gcgatgacct gtcagtttcg cgaaatgaaa
    34621 ctgatgcgta atccggggtg tgaggtgtgc gggcagtaac tgccagcccc aggcctgata
    34681 agtcgcggca agcgtcgcat caggcatttg ctccagacgc cagatgcggc gtgaacgcct
    34741 tatctggcct acggttcggg cgcagatttc caggcgcggc aagcttggtg cactccacaa
    34801 cgttatcagc aattgatgag gatgcagaac gtccggttaa atcgacgttc tgccaaacgc
    34861 tccctgccag tcctgctcaa acttcgccac agcggcatca accgccggat agctaatcat
    34921 ctgttgtgcc acatccagtg gcagagtaat tgattcacat cctgccagta agcagtccag
    34981 cgcctgacgc ggggttttga aactcgcggc taacactttc gcctgcggcg catgcatttt
    35041 caataactgg tgtaagtcgg tcacagtctg aataccgcta ccgccctgag catcaatacg
    35101 attaacgtaa ggcgcaacat attccgcacc tgccagcgcc gacagtagcc cttgtgctgc
    35161 gccatatacc gcggttccca gcgtcggaat cccttccgct tttaacatct taatcgctgc
    35221 cagcccctcg gcggtcaccg gaactttcac cacgatatcc gcaataatag aacgcagctt
    35281 aagcgcgtca ttcaccatcc cttcggcagt ggtagccatt acctgggcaa acagacgccc
    35341 ctgaccgccc atcgcctcgt gaagttgcgg aagcacaacc tccagcggtt ttttacccgc
    35401 ggcgataatg cttgggttag tggtcacacc cgccagcgga aaaatacgtg acagcgcctt
    35461 caccgcaaca acgtctgaag tatccagata cagttccata accatcctca aaatgtactt
    35521 tttgtctgaa tgtagactat cacgggaaaa ctctctgaac agttgacgca catcaatcta
    35581 actttcattc gaaagtattt taatgtttga acgaaacaga gaggcaacta tgattttcaa
    35641 tattcagcgc tactcgaccc atgatggccc cggtatccgc acggtcgtat ttcttaaagg
    35701 ctgttcgctg ggctgccgct ggtgtcagaa cccggaaagc cgcgcccgca cgcaggatct
    35761 gctgtatgac ccacgtctgt gcctggaagg ctgtgagctg tgcgctaagg ccgcgccgga
    35821 cgtgattgag cgcgcgttga atggtttgct tattcatcgg gaaaagttaa ccccggagca
    35881 tctgacggcg ctaaccgact gctgcccgac acaggcgtta accgtgtgtg gtgaagtgaa
    35941 aagcgttgag gagatcatgg cgaccgttct gcgcgataaa ccgttttacg atcgcagcgg
    36001 cggcggctta acgctttctg gcggtgaacc gtttatgcag ccggaaatgg cgatggcgct
    36061 actgcaagcc agccacgagg ctggcattca tactgcggta gaaacctgtc tgcatgtgcc
    36121 gtggaaatat atcgcccctt ctctgcccta tatcgatctg tttcttgccg atttaaaaca
    36181 cgttgccgac gcgccgttta aacagtggac cgacggtaac gccgccagag tgctggataa
    36241 cctgaaaaaa ctcgcctcag cgggcaaaaa aatcattatc cgcgtaccgc tgattcaggg
    36301 ctttaatgcc gacgaaacct ctgtaaaagc cattaccgat tttgccgccg acgagctgca
    36361 cgttggcgaa attcattttc tgccctacca cacgctgggc atcaacaaat atcacttact
    36421 taatctgccc tatgacgccc cggaaaaacc gcttgatgcg ccagaactgc tcgactttgc
    36481 ccagcagtac gcctgccaga aagggttaac cgcgacctta cgaggataac aaccatgacc
    36541 acactgaaac tggacacgct cagcgaccgc attaaagcgc acaaaaatgc gctggtgcat
    36601 attgtgaaac caccagtctg taccgagcgc gcgcagcact ataccgagat gtatcaacaa
    36661 catctcgata agccgatccc ggtacgtcgc gcgctggcac tggcgcatca cctggcgaat
    36721 cgcaccatct ggatcaagca cgatgagttg atcatcggca accaggcaag cgaggttcgc
    36781 gccgcgccga tcttcccgga atataccgtc tcgtggatcg aaaaagagat tgatgatctg
    36841 gcagatcgtc cgggtgctgg ttttgcggtg agcgaggaga acaaacgtgt tctgcatgaa
    36901 gtgtgcccgt ggtggcgcgg tcagacggta caggatcgct gctacggcat gtttaccgat
    36961 gagcaaaaag gtctgctggc gaccggcatc attaaagcgg agggcaatat gacctccggc
    37021 gatgcgcacc tggcggtgaa tttcccgcta ctgctggaaa aagggcttga tggtctgcgt
    37081 gagaaagtgg cggaacgtcg ctcgcgcatc aatctgacgg tactggaaga tctgcacggc
    37141 gagcaattcc tgaaagcgat tgatatcgtg ctggtggcag tcagtgaaca cattgaacgt
    37201 ttcgctgccc tggcgcgtga aatggccacg accgaaaccc gcgaaagccg tcgcgatgaa
    37261 ctgctggcga tggcagaaaa ctgcgatctt atcgcccacc aaccgccgca gactttctgg
    37321 caggcgctgc aactgtgtta cttcatccag ttgatattgc agatcgaatc taacggtcac
    37381 tcagtatctt ttggtcgtat ggaccagtat ctctatccat actatcgccg tgacgttgaa
    37441 ctgaaccaga cactggatcg cgaacacgcc atcgagatgc tgcatagctg ctggttgaaa
    37501 ttgctggaag tgaacaaaat ccgctccggc tcacactcaa aagcctctgc gggaagtccg
    37561 ctgtatcaga acgtcaccat tggcgggcaa aatctggttg atggtcaacc gatggacgcg
    37621 gtaaatccac tctcttatgc gatcctcgaa tcctgcggtc gcctgcgttc gactcagcct
    37681 aacctcagcg tgcgttacca tgcgggtatg agtaacgatt tcctcgatgc ctgtgttcag
    37741 gtgatccgct gtggtttcgg gatgccggcg ttcaacaacg atgaaatcgt catcccggaa
    37801 tttattaaac tcggtattga accgcaggac gcttacgact acgcagcgat tggttgtatc
    37861 gaaaccgccg tcggtggcaa atggggctat cgctgtaccg gcatgagctt tatcaacttc
    37921 gcccgcgtga tgctggcggc gctggaaggc ggtcgtgatg ccaccagcgg caaagtgttc
    37981 ctgccacaag aaaaagcgtt gtcagcgggt aacttcaaca acttcgatga agtaatggac
    38041 gcatgggata cgcaaatccg ttactacacg cgtaaatcaa tcgaaatcga atatgtcgtc
    38101 gacaccatgc tggaagagaa cgtacacgat attctctgct cggcgctggt ggatgactgt
    38161 attgagcgag cgaaaagtat caagcaaggc ggcgcgaaat atgactgggt ttctggcctg
    38221 caggtcggca ttgctaacct cggcaacagc ctggcggcag tgaagaaact ggtatttgaa
    38281 cagggcgcga ttggtcagca acagctggct gccgcactgg cggatgactt cgacggcctg
    38341 actcacgagc agctgcgtca gcggctgatt aacggtgcgc ctaagtacgg caacgacgat
    38401 gatactgtcg atacgctgct ggctcgcgct tatcagacct atatcgacga actaaaacag
    38461 taccataacc cgcgctatgg tcgtggtccg gttggcggca attattacgc gggtacgtca
    38521 tctatctccg ctaacgtacc ctttggcgcg cagacgatgg caacgccgga cggacgtaaa
    38581 gcgcataccc cgctggcaga aggagctagt ccggcctccg gtactgatca tcttggccct
    38641 actgcggtca ttggctcggt gggtaaactg cctacggccg cgattctcgg cggcgtgttg
    38701 ctcaaccaga aactgaatcc ggcaacgctg gagaacgaat ctgacaagca gaaactgatg
    38761 atcctgctac gcaccttctt tgaagtgcat aaaggctggc atattcagta caacatcgtt
    38821 tcccgcgaaa cgctgctgga agcgaaaaaa catccggatc agtaccgcga tctggtagtg
    38881 cgtgtcgcgg gctattccgc cttcttcacc gcgctctctc cagacgctca ggacgatatc
    38941 atcgcccgta ctgaacatat gctgtaatct cctcagcccg gcgtcgtcgt cgccgggcta
    39001 aatcattcac atcatcaatt tcagcctcgc tttcattcga aatataattt gtgctctgcg
    39061 tcacattgtt attacactgt tacggtttca ttttcgagcc aggagcacac ctatgagcgt
    39121 aaaagttatc gtcacagaca tggacggtac ttttcttaac gacgccaaaa cgtacaacca
    39181 accacgtttt atggcgcaat atcaggaact gaaaaagcgc ggcattgagt tcgttgtcgc
    39241 cagcggtaat cagtattacc agcttatttc gttctttcct gagctaaagg atgagatctc
    39301 ttttgtcgcg gaaaacggcg cactggttta cgaacatggc aagcagttgt tccacggcga
    39361 actgacccga catgaatcgc ggattgttat tggcgagttg ctaaaagata agcaactcaa
    39421 ttttgtcgct tgcggtctgc aaagtgcata tgtcagcgaa aatgcccccg aagcattcgt
    39481 cgcactgatg gcaaaacact accatcgcct gaaacctgta aaagattatc aggagattga
    39541 cgacgtactg ttcaagtttt cgctcaacct gccggatgaa caaatcccgt tagtgatcga
    39601 caaactgcac atagcgctgg atggcattat gaaacccgtc accagtggtt ttggctttat
    39661 cgacctgatt attcccggtc tacataaagc aaacggtatt tcgcggttac tgaaacgctg
    39721 ggatctgtca ccgcaaaatg tggtagcgat tggcgacagc ggtaacgatg cggagatgct
    39781 gaaaatggcg cgttattcct ttgcgatggg caatgctgcg gaaaacatta aacaaatcgc
    39841 ccgttatgct accgatgata ataatcatga aggcgcgctg aacgtgattc aggctgtgct
    39901 ggataacaga tcccctttta acagctgacc tctctaccgg agccatgcgc tccggttttc
    39961 ccttcttttt acatcctgta catcacatca aatcattaaa cttgcattaa cttatttata
    40021 acttatattg tcacatgcaa atcagcatag tttcgaatga aagttaatgc gaggtggtta
    40081 tggcttctac ttttaccagc aacacattgc ctgccgatca caaagcagct atccgtcaga
    40141 tgaagcacgc gctgcgggcg cagcttggcg acgtccagca gatctttaat cagctaagcg
    40201 atgacattgc cacgcgagtg gctgaaatca acgcactcaa agcacagggc gatgcagtct
    40261 ggccggtgct gtcttatgcc gatatcaaag caggtcatgt tactgcagag caacgcgaac
    40321 agattaaacg tcgcggttgt gcggtgataa aaggccattt cccccgcgaa caagcgctag
    40381 gctgggatca gtcgatgctg gactatctgg accgcaaccg ctttgatgag gtctacaaag
    40441 gccccggcga taatttcttc gggacgctca gcgcttcacg tcccgagatt taccccatct
    40501 actggtcgca ggcgcaaatg caggcccgcc agagtgaaga aatggcgaat gcgcagtcgt
    40561 ttctcaatcg tctgtggaca tttgaaagtg atggaaagca atggtttaac ccggatgtga
    40621 gcgtcatcta ccctgaccgt atccgccgcc gtccgcccgg aacggcctcc aaaggtctcg
    40681 gagcgcatac cgactccggg gcactggaac gctggctgct tccagcgtat cagcgcgttt
    40741 tcgccaacgt ctttaatggc aatctggcgc aatatgatcc ctggcatgcg gcacatcgta
    40801 cagaagttga agagtacacg gtggacaaca ccaccaaatg ttccgtgttt cggacattcc
    40861 agggctggac agcgctctct gatatgctgc ctggtcaggg actgctgcac gtcgtgccca
    40921 ttcctgaagc catggcgtac gtgctgttac gtccgctgct tgatgatgtg ccggaggatg
    40981 aactgtgcgg cgtagcgccc ggaagagtgt tgccggtatc agagcaatgg catccactgt
    41041 tgattgaggc attaaccagc attccacaac tcgaagccgg agactccgtc tggtggcact
    41101 gcgacgtcat ccattccgtt gcccccgttg aaaatcaaca gggttggggc aacgtgatgt
    41161 acattcctgc ggcaccgatg tgcgagaaaa atcttgccta cgcgcacaag gtgaaggccg
    41221 cactggaaaa aggcgcatcg ccgggcgact tcccgcgcga ggactatgaa acaaactggg
    41281 aaggacgctt tacgcttgcc gacctcaaca ttcacggtaa gcgagcgctg ggaatcgaca
    41341 gctgattgtc gtacagccct tcccgttcca cggcggtgtt cccttttcct gggcgaaccc
    41401 gccgcaccga ctcccgcacc gctaatcgtc cgtgcagcag cagcgagccc accggagcat
    41461 ccgggcgaat cagccgctgt tgcaacattt gcaccgcttc attgcctagc tcatcgcgtg
    41521 gcacatgcac agccgtcagg ggaacatcct cgattgccgc aagattaaag ccgtcgatac
    41581 tcatcaccga gacatcctgt ggtacgcgca gaccacgacg atgtagcgca tttaccgttc
    41641 ccgccgccat aaaatccccg ccgaccagaa acgccgtcgg caacgtcttg ccattggcgg
    41701 catccagcca cgctccgacc ttttcttccg cttctttagc gctaaaactg ctgatattca
    41761 gcaaatgacg gtcatggtga aaggccagat tatgctgacg ccatgattct ttaatccctg
    41821 caaaccgctg ctccatagtg tagcggcgca ggcacataac gttcatcacc tcccggtgac
    41881 ccatttcaaa cagatagcgg gcggcgaacg caccaattaa ccgatggtcc ggcgcaatcg
    41941 tcgggaggcg cattcgttca tcacggcagt tgatcagcac gcaaggctta gcgagatcgg
    42001 cggccagatc atggatgtgc ggatcgtcaa tccccagcag gatcgccgcc tgcgtatctg
    42061 cttcattcat ccgcgagaga aatagcgcgg gatcgctgtc aaactcctcc agcgcgcagt
    42121 aacgcagccg cacttcatgc ggcgataacg ctttgctgat gctctggatc acacggtaat
    42181 aaaagatatc agatcgttag tcaaacgcgc gttgcggcgc aaaaataatc aggttgttca
    42241 gcaacatacg acctgctgcc atgccatcca tcacgcccaa ctcacgcgcg caggccagca
    42301 cctgttcgcg agcgcgtgca ctggtattcg ctttgccagc cagcacccgc gaaaccgtac
    42361 tcggcgataa tccggtacgt gcggcgatat cggcgatttt cagcttcttg tccattttgt
    42421 gatctgcctc taattcggaa atgacagaat tttcatgagc aaaaaagccc attctgtctg
    42481 gcattaaatc catttcagta atgtatatca gccactcatg gaaaaacgtg cacaaaaccc
    42541 gctttctttc gcttttagtg tctcttactg tgaattggta gaacaacttc catacaagaa
    42601 caatggaaaa acgaacaata aagactttat ttatcaaaag gttaaaagtg gtgtgacaac
    42661 tccagtctga cgttgccgcc ccccctatac cattctgtgg agtgcatatg agtcagggta
    42721 tcaataacga tatgactgcc agtaaaccgc gccatattgt caaaaatctg cgttggtgga
    42781 tgctggtcct ttttttgctc ggtgttactg tcaactacat cacacgtaat tcgctgggta
    42841 ttctcgcccc cgagttgaaa agcagcctgg ggattaccac cgaacaatat tcctggattg
    42901 taggtgcttt ccaactcgcc tataccctat ttcaaccgtt atgcgggtgg ctgattgacg
    42961 tcattggcct caaactgggc tttatgatct gcgcggggct gtgggcgctg gcctgtctga
    43021 tgcatgcggg ggcgggaaac tgggtacatc tggcgctgtt gcgcttcttt atgggcggtg
    43081 cggaagccgc ggccaccccg gcaaacgcca aaactatcgg tgaatggttt ccaaaatcag
    43141 aacgcccgat cgccgcaggc tgggcaggcg tcggtttttc catcggtgcc atgctggccc
    43201 caccgattat ctattttgcc cacgcttcat tcggctggca gggcgcattt atgttcactg
    43261 gcatcctggc gatgctgtgg gtggtgctgt ggtgggcgtt ctatcacaac ccggataagc
    43321 atcctaacct cagcaaagcc gagctggact ttatccgcca ggataacgaa gctcccccgg
    43381 tcaagttacc ttttctgacc gcactgaaaa ccgtgggcaa aaataaacgc ttttacggta
    43441 tcgctatccc agcctttatg gcagaaccgg cgtgggcggt gatgagtttc tgggttccgc
    43501 tatacctgtc caaatcctat ggcatggacc tgaagcagat cgcactcttc gcctggttgc
    43561 cgttcctcgc cgctgatctt ggcagtattg ccagcggcta tctgaccaaa ctttacaccc
    43621 gcctgtttgg gctgagtcgt gtgaactccg ttgtcgcatc atcggtcagt ggcgcattcc
    43681 tgatggtttc gctggcggtg atggccttta tcaataaccc gtatatcgcc atcgtcctta
    43741 tctccatagg cggcttcggt caccagatca tctcctgcat gcttagcgca ttagtagtgg
    43801 aatccttcga caaaggtcag atggccactg ttaacggcat gcgcggttct gccgcgtgga
    43861 tcgcaagttt cctgttctcc ctgattatcg gggttactgc tgacaaaatc ggctttaacc
    43921 ccctgtttat cgccatgggc ttctttgacc tgattggcgc tttcttcctg gtcaccttta
    43981 ttgctgaacg tcgcgcaaaa cgcgcctgag agtggatgta aacatgaaaa cgctgaaaaa
    44041 ctggaccctg cacaaacagt ctgcccacca cgttgaactg ctggtcgatg gccagcatat
    44101 cctgtgcctg tacgtgctgg aagaaaatct gttccgcgtg ctgttaaaac gcaaaggcga
    44161 gctggcgctg gatcgcacct ggagcattgc tccggcgcag gatgtgccat gggaagggcg
    44221 cagccgcgaa gatctcagcg gctttagcct gcccgcgtgg accttgaacc agcacgacaa
    44281 caccgtggtt atcgccaccg agtcactgcg tgccaccgtt caccagccgc tgtggctgga
    44341 gtggcactat cgtaacaacg aaggcgaatg gctgccgtta gtgaatgacc gaccgaccag
    44401 cgcttatctg ctgaatgccc acggtgacgg tgtggcgcac tatcagagcc gtcgtaaaga
    44461 tgaacgcttt tatggcctcg gagataaagc cggcgacctg caacgcaacg gtaaacgtta
    44521 cgagatgcgt aacctcgacg cgatgggcta caacgccgtg agtactgacc cgctgtacaa
    44581 acacattcca ttcaccatca cccgccgcga tgacgttagc ttcggcctgt tttatgacaa
    44641 cctcagcagc tgctggctgg atctgggaaa cgagatcgac aactaccaca ccgcctatcg
    44701 ccgctggcgg gcggaagcgg gtgatatcga ctactacctg tttacaggcg aacgcgtact
    44761 tgatatcacc aaagcctttg tacgcctgac cggaaaaact ctgttcgggc cgaaatggag
    44821 cctgggctac agcggttcaa ctatgcacta caccgatgcc ccggacgcac aaaatcagtt
    44881 gatgaacttt atccgcctgt gtgaagaaca tgcgattccc tgcgattcgt tccagctctc
    44941 ttccggttat acctcaatta acggcaagcg ctatgtgttc aactggaatt acgacaaagt
    45001 gccgcagccg aaagtgatga gccaggcatt tcacgatgcc ggtatgcacc tggctgccaa
    45061 tatcaagccg tgcctgttgc aggatcaccc acgctataac gaagtggcag aaagaggact
    45121 gttcatccgt gattcagaaa cagatgaacc agaacgttcc agcttctggg atgacgaagg
    45181 ttctaacctt gactttacta atccgcagac catccagtgg tggcaggaag gcgtgaccac
    45241 acagcttctg gagatgggta tcgactccac ctggaacgac aacaatgaat tcgaagtgtg
    45301 ggacggtgaa gcacgctgtc acggctttgg tcagacgatc gcgatcaaac atattcgccc
    45361 ggtgatgcca ctgctgatga tgcgagcctc gatggaagcc cagcaacgtt tcgctccgga
    45421 aaaacgtccg tacttgatct cccgctccgg ctgcgcggga atgcagcgct atgtgcagac
    45481 ctggagcggc gataaccgca ctagctggga cactctgcgc tacaacaccc gcatgggtct
    45541 ggggatgagc ctctccgggc tgtataacct cggtcacgac gtcggcggtt tctccggtga
    45601 taagccggac ccggaactgt ttgtgcgctg ggtacaaaac ggcgtgatgc atccgcgctt
    45661 tacgattcac tcgtggaacg atgaccatac cgtaaacgaa ccgtggatgt atccgggcgt
    45721 cactccggcg atccgcagcg ctattgagtt gcgctatcgc ctgctgccct acttttatac
    45781 cctgatgtgg caggcatacg ccgatgatga accaatgcta cgtccgactt tccttgacca
    45841 cgagcacgac gttcagactt ttgaagagtg tgatgacttc ctgcttggtc gcgatatttt
    45901 ggttgccagc gtcgtagagc aaggcgagcg ccagcgccgt gtatggctgc cggataacga
    45961 aactggctgg tacgatttct acaacggcga atggttcagt ggcggtcagt ggatcaccct
    46021 cgacgcaccg ctggagaaac tgccgctgat ggtgcgtgcc ggggctggtc taccgctcag
    46081 caaacgcatc acctatgtga gcgcagaaca agacgatacc cgcgaactga aactgttccc
    46141 gctgaaaggc gtgggcacaa cgtccggcct gctgtttgaa gacgatggcg aaagctgggg
    46201 ctaccaaact ggtaatgcgc tttgggtgga atgggaaatg gtttgcgatg gggcgaccat
    46261 caacctgaaa gtcaacgcgc gcggggatta tcgtcctgca tggagtgtac tgaaagtgtc
    46321 attaccagtg gaagaaaaac gcacgctgct ggtcaatggt gttgaaggga gtgaatggat
    46381 acgttaaacc attaccgggg ccgggaggcg actgcgcctt acccggtcca gccatcgaat
    46441 ccttttcctc agtatttcac gctgcagaaa ggcagcaaac ctgtataccc cgggagctta
    46501 aataagtaag tgaccggggt gaacaggtga agccaatgca tctgccgcat gaaagacggc
    46561 gggaaattaa ccgtcgatcc ctttactacg cagataatct tcgtaattac cgctaaagtc
    46621 gatcacgcgt tccggggtga tttccagaat acgggtcgcc agggagctta cgaactcacg
    46681 gtcgtgtgaa acaaagatca gcgtgccctg atacagttcc agcgccatgt tcagcgactc
    46741 aatagattcc atatccaggt ggttggtcgg ttcgtccatg atcagaatgt tcggcttctg
    46801 catcattaac ttaccaaaca gcatccgccc tttttcccca ccggaaagca ctttagctgg
    46861 ctttttaatg tcgtcctggc tgaacagcaa acgaccgaga atgctgcgta ccgcctgctc
    46921 gtcatcgcct tcctgcttcc actggctcat ccattcgaac acggtcagat cattttcaaa
    46981 ctcatattcg tggtcctgag catagtaacc aatgcgcgcg ttttcagacc attttacggt
    47041 gccgctgtcc ggttgcagat cgcccaccag cgttttcaac agcgttgatt taccgacgcc
    47101 gttggtaccc agtaccgcca gtttttcacc gacttccagc agcaggttga gatttttaaa
    47161 cagcggaccg ttatcaaacc ctttggtcag accttccact tccagcgcgt tacggaacag
    47221 tttcttatcc tgttcaaaac ggatgaacgg gttctgacgg ctggaggctt tcacctcttc
    47281 cagtttgatt ttatcaatct ggcgcgcgcg cgaagttgcc tggcgagatt tcgaggcgtt
    47341 ggcgctaaag cggctaacga aagattgcag ctcagcaatc tgcgccttct tcttggcgtt
    47401 atcagccagc agacgttcac gcgcctgggt cgccgccgtc atgtactcat cgtagttgcc
    47461 cggataaacg cgcagctcgc cgtaatccag atccgccatg tgggtacaaa ccatgttaag
    47521 gaagtgacgg tcgtgcgaga tgatgatcat ggtgctgtca cgctcgttca gcacctgttc
    47581 cagccaacga atggtgtcga tgtcgaggtt gttggtcggt tcgtcgagca ggagaatgtc
    47641 cggatcagca aacagcgcct gcgccagcag cacacgcagc ttccagccag gagcaacttc
    47701 actcatcggg ccgtagtgct gttccactgg aattcccacg ccaagcaaca gttcaccggc
    47761 gcgagcttcc gcagagtaac cgtccatttc gccgtatttc acttccagat cggccacttt
    47821 atagccgtct tcctcactca tttccggcaa agcatagatg cggtcgcgct cctgcttcac
    47881 ttcccataat tctttatgcc ccatgatcac cgtatccagc acagtgaact cttcaaaggc
    47941 aaactgatcc tgacgcagct taccaatgcg ctcgttggga tcgagggaaa cgttacccag
    48001 cgtcggctct aagtcgccgc cgaggatctt cataaaggtg gatttaccac taccgttcgc
    48061 gccaatcagg ccgtaacggt tgccgccgcc aaacttgacg gaaatgtttt caaacaacgg
    48121 cttactgccg aactgcatgg tgacgttact ggaaactaac acaggcgtat cctgaaaaga
    48181 gatatgacaa accgcgtatt atgccataag tctgaaagaa gatcccgtcc cccgcttaag
    48241 gtctacactc ttcccaaagg caaaaaatgt gatttcgtac acatctgatt tcactgtgag
    48301 ctggaatgaa cttataatgc gcttccaata ctctaatatt ctcaacccaa tggcctgcca
    48361 ggcacaaaat ctcgcttaac atgaatatga aattgaaaac attattcgca gcggccttcg
    48421 ctgttgtcgg cttttgcagt accgcctctg cggtaactta tcctctgcca accgacggga
    48481 gtcgcctggt tggtcagaat caggtaatca ccattcctga aggtaacact cagccgctgg
    48541 agtattttgc cgccgagtac cagatgggtc tttccaacat gatggaagct aacccgggtg
    48601 tggatacctt cctgccgaaa ggcggtactg tactgaacat tccgcagcag ctgatcctgc
    48661 cggataccgt tcatgaaggc attgtcatta acagcgcaga gatgcgtctc tattactatc
    48721 cgaaaggcag caacaccgtt atcgtgctgc ccatcggcat tggtcagtta ggcaaagaca
    48781 cgcctatcaa ctggaccacc aaagttgagc gtaagaaagc aggcccgacc tggacgccga
    48841 ccgccaaaat gcacgcagag taccgcgctg cgggcgaacc gcttccggct gtcgttccgg
    48901 caggtccgga taacccgatg ggtctgtatg cactctacat cggtcgcctg tacgctatcc
    48961 atggcaccaa cgccaacttc ggtatcggcc tgcgtgtaag tcatggctgt gtgcgtctgc
    49021 gtaacgaaga cattaaattc ctgttcgaga aagtgcctgt cggtactcgc gtgcagttta
    49081 ttgatgagcc ggtaaaagcg accaccgagc cagacggcag ccgttatatt gaagtccata
    49141 atccgctgtc taccaccgaa gcccagtttg aaggtcagga aattgtgcca attaccctga
    49201 cgaagagcgt gcagacagtg accggtcagc cagatgttga ccaggttgtt cttgatgaag
    49261 cgatcaaaaa tcgttctggg atgccggttc gtctgaatta atcgtcaaaa cgtaaaacag
    49321 aggcggactc atcatccgcc ttttttattt ggccagaccc tagttggccg ggagcataac
    49381 gaataaaacg tatcccacca gcgccgccca caacagcatc ggtatcgaat aaagatgaaa
    49441 acgccaccag atacggcgat cgttcgccat ccgtaacgca atcaaatttg ccagcgatcc
    49501 gggtaataaa ccaaagccac ctacgtttac cgcccatgcc aataataaag acggtggcac
    49561 ataattgagc agcaaaatcg tgctcggcac attactgatc acctgcgata aaccgattgc
    49621 cgttaaccat aacccgggtt cagataaatg actcacgtta cccaacacgc cttgcaacgc
    49681 tggaagctgg gtcagtaaat ggacgtcgat aaacatcgcc ataaacacca gcagcagcgt
    49741 ccagtccaca ctgagcacca cgcaacgtgc cagcagcgca aagccggccg ccacaatcac
    49801 cagtccccac agctcttgtt tgaactccag cgccgtcaga aaaacgatat acagccccag
    49861 acaactccac accagccgcg gtttccactc cggcgtttgc gcccccgtat ggtattgcag
    49921 cgcctttcca gggaaacaac accagcacaa cagcaggagt gtcagcatca ttgcgccagc
    49981 cagcggtgcc atttgggcaa taaatccggc aaacgaaaga ccagaacgtc cccagataag
    50041 aatattttgc gggttgccaa ttggcgtcag tagcgaacca gcgttgactg ccagcgcctc
    50101 aaaaataatc agccgattaa ccgggatctc acacagtctt tttagcgtga tagtcagcgg
    50161 aacaactata aacagcgcga catcgttggt cagaaaggta gaaagcagcg ccgccgccag
    50221 taccataaac atcgccagcc gacgctccgt agcaaaacgg cgcaccattt tgcgccccag
    50281 cacatcaaaa taaccgctta actcgacacc tttggtcagc agcatcaggc cgcttaaggt
    50341 gatgatggtg tgccagtcga tagcagcagg ccaggatttc ggtgcaaagg gaacgaaaaa
    50401 gcttaatccg atgccaacaa gaattaataa ctgaaaaaaa cgatcgcctt gcagcgtgct
    50461 taaaaaaggc aggctcattt ggcaccgtgt ttctgggtaa acaaacgaaa agcgtcgagc
    50521 gtctcttcac taacatggtg ctccatgcct tccgcgtcgc gacgggcgat ttccggactg
    50581 acgcccaaca ccaacaagaa attttcgact atctgatgtc gctcgcggct ttcctgcgcc
    50641 agcttctctc cttctgccgt taaaaacacg ccacgccagg ggatcatttc aatcagcccc
    50701 atggttgcca gtcgcttaag cattttagcc accgtcggtt gcgaaactcc caaacgagca
    50761 gccatgtcta cctgacgagc ttcccccact tccctgatca agtcagaaat cagctcaacg
    50821 taatcatcaa taagctcgcg ccgatgcgcc tctctgacct ggcggaaccc ttcaacgtgc
    50881 tcttccacgt tcactaactg cgtcactttt tttgctgttg gcgtacctgc gcgacgactc
    50941 attgtgcttc ctcattatgg tgacgcatac atagcgttct catttcgtgc gcacattgta
    51001 aaccagagtt gcgaaggtac aaaaaattaa cgttttagca atagctatat aatatagcct
    51061 gtgctatatc tgtatgtaat gcaatcatcc ctcaaggatc gacgggatta gcaagtcagg
    51121 aggtcttatg aatgagttca agaggtgtat gcgcgtgttt agtcattctc cctttaaagt
    51181 acggttaatg ctgctctcta tgttgtgcga tatggtcaac aacaaaccgc agcaagataa
    51241 accttccgat aaatagcggc gtcgcggtac gccgcttcac tcctgctttt atgcaggcac
    51301 aacgcgtttt ggtctgaaaa accccacttt ttgtcggatt tgcaatcccc ttcgcaaaag
    51361 atttgttcgt cagtagttga cctgaacggc ggctcgctct atcttcttgc agccctgcgt
    51421 atattgcggc tcgcggatgc ggaccccttt cccctctcca cgcactcttg caggtattga
    51481 cccttgacgc cagggtaagc acatggcgtt tgttacgata gtggcatatg aatttaaccc
    51541 tcaaagaatc gcttgttacc cgtagccggg tatttagccc gtggactgcg ttctactttt
    51601 tacagtcgct attaattaac ctcggcttag gttatccctt cagtttgctc tacaccgctg
    51661 cgtttacggc tattttgctt ttgctatggc gaacattgcc tcgcgtacaa aaagttctgg
    51721 tcggtgtcag ttcgctggtg gcggcttgtt atttcccttt tgctcaggcc tacggcgcgc
    51781 ctaatttcaa tacattgctg gcattgcact ccaccaatat ggaagagtcg accgaaatcc
    51841 tgacgatttt tccgtggtac agctacctgg tcggcttatt tatttttgcg ctcggcgtaa
    51901 tagcaatcag gcgaaaaaaa gagaatgaaa aagcgcgctg gaataccttc gacagcctgt
    51961 gtctggtatt cagtgtggcg acattttttg ttgctcccgt gcaaaacctg gcctggggcg
    52021 gcgtatttaa actgaaagat actggctatc cggtatttcg ttttgctaag gatgtcatcg
    52081 tcaataataa cgaggtgatt gaagagcaag aacggatggc aaaactttcc ggaatgaaag
    52141 atacctggac ggtcactgcc gttaagccga agtatcagac ctatgtggtg gtgatcggtg
    52201 aaagcgcgcg tcgcgatgcc ctcggtgcct ttggcggtca ctgggacaat accccgtttg
    52261 ccagcagcgt taacggtttg atatttgctg actacattgc cgccagtggc tccacgcaga
    52321 aatcgcttgg cttaacgctc aatcgcgttg tcgatggcaa accacagttt caggataact
    52381 ttgtcaccct ggcaaatcgc gcgggcttcc agacctggtg gttttccaac caggggcaaa
    52441 tcggcgaata cgataccgct atcgccagca tcgccaaacg tgcagatgaa gtgtacttcc
    52501 tgaaagaagg taattttgaa gcagataaaa acacgaaaga cgaagcgtta ctggatatga
    52561 ccgctcaagt gctggcgcaa gagcactcgc aaccgcagct gattgtttta catctgatgg
    52621 gctcacatcc gcaggcctgc gaccggacac aaggcaaata cgaaaccttt gtgcaatcga
    52681 aagaaacgtc gtgctatctc tataccatga cgcaaacgga cgatttactg cgtaagctgt
    52741 acgatcagtt acgcaacagc ggcagcagct tctcgctggt ttacttttct gaccacggtc
    52801 tggcctttaa agagcgcggc aaagacgtgc aataccttgc ccatgatgat aaatatcagc
    52861 agaatttcca ggtgcctttt atggtcattt cgagcgacga taaagcgcat cgggtgatta
    52921 aagcccgccg ctcagccaat gacttcttag gttttttctc ccagtggacg ggaattaaag
    52981 cgaaggaaat taacatcaaa tacccgttta tatctgagaa gaaagccggg ccgatataca
    53041 tcaccaactt ccagttacag aaggtagatt acaaccatct cggaaccgat attttcgacc
    53101 cgaaacctta aaaacaaaaa tccgccccga gaggcggatt ttttatatca ccgaagtgat
    53161 tagaagcggt aaccaacacc ggcaatccag gtgcctacgt caacgctacg aatacggctc
    53221 tgctcgtaag agaagtccag agcaacgttt tccatcgggt tgaactgcag accagcaccg
    53281 taggagaaac cgtagtcgct ggtgtcgtgt ttgtaggtcg ggtattcagt ggtctggaat
    53341 ttaccataac ccacacccac tacaccgtag atgcttgccc agtcgttaat gcggtaagcc
    53401 ggaccagcag tgatgccgta gtactggttt ttgttgtagt caccagagct tgcagtacgg
    53461 cttttctcgg tgtaagtgaa agaaccgatc acacccagcg ggctgttgtc ttcttcatag
    53521 cggtatttca ggttgaaacc gcccattttg ttcatttggc cctgagcgtc gctctgtgcg
    53581 taaccgccag ttacagtaga agtcgcagct acggaagtac ctgcggtgaa agccagaact
    53641 gcggccagtg ctgaaagaca tgcaattttt ttcataacca cctcaaatgt gattcaaata
    53701 agtcctaagt tttaaatata tcaaaaatta atgggaaact cttcgcgatt tgtgatgtct
    53761 aacgggccat ttcatgtaac agaacgtttc catacaccgc tatccatcta aatttaaatc
    53821 actttttcag agaactgcgt aagtattacg catgttttcc ctgtcattca tccagattat
    53881 tcctaatcac cagactaatg attccatcaa tcctggcgca ttttagtcaa aacgggggaa
    53941 aattttttca acaaatgctc aaccagcatt gggtatatcc agtacactcc acgctttact
    54001 taggtttaga tatttgtggg agaaaggatg cctggttcat tacgtaaaat gccggtctgg
    54061 ttaccaatag tcatattgct cgttgccatg gcgtctattc agagtggagc ctcgttagct
    54121 aagtcacttt ttcctctggt gggcgcaccg ggggtcactg cgctgcgtct ggcattaggc
    54181 acgctgatcc tcatcgcgtt ctttaagcca tggcgactgc gctttgccaa agagcagcgg
    54241 ttaccgctgt tgttttacgg cgtttcgctg ggggggatga attatctttt ttatctttct
    54301 attcagacgg taccgctggg tattgcggtg gcgctggagt tcaccggacc actggcggtg
    54361 gcgctgttct cttctcgtcg cccggtagat ttcgtctggg ttgttctggc ggttcttggt
    54421 ctgtggttcc tgctaccgct ggggcaagac gtttcccatg tcgatttaac cggctgtgcg
    54481 ctggctctgg gcgccggggc ttgttgggct atttacattt taagtgggca acgcgcagga
    54541 gcggaacatg gccctgcgac ggtggcaatt ggttcgttga ttgcagcgtt aattttcgtg
    54601 ccaattggag cgcttcaggc tggtgaagca ctctggcact ggtcggttat tccattgggt
    54661 ctggcggtcg ctattctctc gaccgctctg ccttattcgc tggaaatgat tgccctcacc
    54721 cgtttgccaa cacgcacatt tggtacgcta atgagcatgg aacctgcgct ggctgccgtt
    54781 tccgggatga ttttcctcgg agaaacactg acacccatac agctgctggc gctcggcgct
    54841 atcatcgccg cttcaatggg ttctacgctg acagtacgca aagagagcaa aataaaagaa
    54901 ttagatataa attaaattta catttctgca tggttatgca taaccatgca gattttctcg
    54961 ctacttttcc tctacaccgt ctttatatat cgaattatgc aaaagcatat ttattccgaa
    55021 aattcctggc gagcaaataa ataagaattg ttcttattaa tatatctaac tcattgagtt
    55081 tttattggtt ttgttttttc acgcttgtta ccactattag tgtgatagga acagccagaa
    55141 tagcggaaca catagctggt gctatactta gtctcgttaa ttactgggac ataacatcaa
    55201 gaggatatga aattatgagt accgctaaat tagttaaatc aaaagcgacc aatctgcttt
    55261 atacccgcaa cgatgtctct gacagcgaga aaaaagcaac agtagagttg ctgaatcgcc
    55321 aggttatcca gtttattgat ctttctttga ttaccaaaca agcgcactgg aacatgcgcg
    55381 gcgctaactt cattgccgta catgaaatgc tggatggctt ccgcactgca ctgatcgatc
    55441 atctggatac catggcagaa cgtgcagtgc agctgggcgg tgtagctctg gggaccactc
    55501 aagttattaa cagcaaaact ccgctgaaaa gttacccgct ggacatccac aacgttcagg
    55561 atcacctgaa agagctggct gaccgttacg caatcgtcgc taatgacgta cgcaaagcga
    55621 ttggcgaagc gaaagatgac gacaccgcag atatcctgac cgccgcgtct cgcgacctgg
    55681 ataaattcct gtggtttatc gagtctaaca tcgaataaat ccatcgctga tggtgcagaa
    55741 ctttagtaca cgataaaagc ggcttcctga caggaggccg ttttgttttg cagcccacct
    55801 caacgcactt atttagtgca tccatctgct atctccagct gattaagtaa attttttgta
    55861 tccacatcat cacacaatcg ttacataaag attgtttttt catcaggttt tacgctaaat
    55921 aatcactgtg ttgagtgcac aattttagcg caccagtttg gtgccccaga atggtgcatc
    55981 ttcagggtat tgccctataa atcgtgcatc acgtttttac cgcatctcga taaatcaatg
    56041 agttgcaaaa ctggcacgat tttttcatat atgtgaatgt cacgcagggg atcgtcccgt
    56101 ggatagaaaa aaggaaatgc tatgaagtct gtattaaaag tttcactggc tgcactgacc
    56161 ctggcttttg cggtttcttc tcatgccgcg gataaaaaat tagttgtcgc gacggatacc
    56221 gccttcgttc cgtttgaatt taaacagggc gataaatacg tgggctttga cgttgatctg
    56281 tgggctgcca tcgctaaaga actgaagctg gattacgaac tgaagccgat ggatttcagt
    56341 gggatcattc cggcactgca aaccaaaaac gtcgatctgg cgctggcggg cattaccatc
    56401 accgacgagc gtaaaaaagc gatcgatttc tctgacggct actacaaaag cggcctgtta
    56461 gtgatggtga aagccaacaa taacgatgtg aaaagcgtga aagatctcga cgggaaagtg
    56521 gttgctgtga agagcggcac tggctccgtt gattacgcga aagcaaacat caaaactaaa
    56581 gatctgcgtc agttcccgaa catcgataac gcctatatgg aactgggcac caaccgcgca
    56641 gacgccgttc tgcacgatac gccaaacatt ctgtacttca tcaaaaccgc cggtaacggt
    56701 cagttcaaag cggtaggtga ctctctggaa gcacagcaat acggtattgc gttcccgaaa
    56761 ggtagcgacg agctgcgtga caaagtcaac ggcgcgttga aaaccctgcg cgagaacgga
    56821 acttacaacg aaatctacaa aaaatggttc ggtactgaac cgaaataata acgctacgcc
    56881 tgtaaggcgc actggcagtt ccctctcccc tctggggaga ggattagggt gaggggcgca
    56941 aacccgctcc ggggccatta attaccctga atttgattat ttacaccacg gtaacaggaa
    57001 caacatatgc agtttgactg gagtgccatc tggcctgcca ttccgcttct gattgaaggt
    57061 gccaaaatga ccctgtggat ctcggtcctc ggtctggctg gcggcctggt gatcggattg
    57121 ctggcaggtt ttgcacgcac cttcggtggt tggatagcca accacgtcgc gctggtcttt
    57181 attgaagtga tccgcggcac acctatcgtc gtccaagtga tgtttatcta tttcgccctg
    57241 ccgatggcgt ttaacgactt acgcatcgac ccgtttactg cggcggtggt caccatcatg
    57301 atcaactctg gcgcgtacat tgcggaaatc acgcgtggtg cggtgctgtc tattcataaa
    57361 ggttttcgtg aagcaggact ggcgctcggt ctttcacgtt gggaaaccat tcgctacgtc
    57421 attttaccgc tggcactgcg tcgtatgctg ccgccgctgg gtaaccagtg gatcatcagc
    57481 attaaagaca cctcgctgtt tattgttatc ggcgtggcgg aactgacccg tcaggggcaa
    57541 gaaattattg ccggtaactt ccgcgccctt gagatctgga gcgccgtggc ggtgttctat
    57601 ctgattatta ccctggtgct gagctttatt ctgcgtcgtc tggaaagaag gatgaaaatc
    57661 ctgtgattga atttaaaaac gtctccaagc attttggtcc aacccaggtg ctgcacaata
    57721 tcgatttgaa cattgctcag ggcgaagtcg tggtgattat cgggccgtcc ggttccggta
    57781 aatcgaccct gctgcgctgc atcaacaaac tggaagaaat cacttccggc gatctgattg
    57841 tcgatggcct gaaggttaac gatccgaaag ttgacgagcg cctgattcgc caggaagcag
    57901 gtatggtgtt ccagcagttt tacctcttcc cgcatctgac ggcgctggaa aacgtcatgt
    57961 ttggtccgct acgcgtgcgt ggcgcgaaca aagaagaggc ggaaaaactg gcgcgtgagc
    58021 tgctggcgaa agtcggtctg gcagaacgtg cacatcacta cccttccgaa ctttctggtg
    58081 gtcaacagca gcgtgtggcg atcgcacgcg cgctggcggt gaagccgaaa atgatgctgt
    58141 ttgatgaacc gacttccgct cttgacccgg aactgcgcca tgaagtgctg aaggttatgc
    58201 aggatctggc tgaagaaggg atgacgatgg tgatcgtgac acacgaaatc ggttttgccg
    58261 agaaagtagc ttcgcgcctg atctttatcg acaaaggccg gattgcggaa gatggcgatc
    58321 cgcaggtgtt gatcaagaac ccaccgagcc agcgcttgca ggaatttttg cagcacgtct
    58381 cttaacttct cagcctccct ttccccgaaa gggaggcaca ccagattcct ctcatttaaa
    58441 atcgctcctc ccccagcatc tatacttatc tttttgctct gttttctcac tggaggagtc
    58501 atgcggtgga tcctgttcat cctcttctgc ctgctgggcg cacctgccca cgcggtatcc
    58561 atacccggcg ttacaaccac aacgacaacg gactcaacga ctgaaccggc cccggaaccg
    58621 gatatcgaac aaaaaaaagc ggcctatggc gcactggcgg atgtgctgga taatgacacc
    58681 tcgcgtaaag agttgatcga ccagttgcgc accgtcgccg cgacgccccc ggcagaaccc
    58741 gtaccgaaga tcgtgccgcc gacgctggtt gaagagcaaa ccgtgctgca aaaggtcacc
    58801 gaagtcagcc gccattatgg tgaagccctt tccgcccgct tcgggcaact ttatcgcaat
    58861 atcaccggct ccccgcataa gccgtttaat ccacaaacct tcagcaatgc gttgacccat
    58921 ttttcaatgt tagcggtatt agtgtttggt ttttactggc tgattcgcct gtgcgcactt
    58981 ccgctgtatc gcaaaatggg ccagtgggcg cggcaaaaaa atcgtgagcg cagtaactgg
    59041 ttgcagcttc cggcgatgat tatcggggcg tttattatcg acctgctgtt actggcactg
    59101 acattatttg tcggtcaggt tttaagcgac aacctgaatg cgggcagtcg caccatcgct
    59161 ttccaacaaa gtttgtttct caacgccttt gccctgattg aatttttcaa agccgtacta
    59221 cgcctgattt tttgcccaaa cgtggctgaa ctgcgcccgt tcacgattca tgacgagacc
    59281 gcccgttact ggagtcgtcg cctgagctgg ttaagcagcc tgattggcta tggtctgatt
    59341 gtggctgtgc cgattatctc taatcaggtg aatgtacaga taggtgcgct ggcgaacgtc
    59401 atcattatgc tgtgcatgac ggtctgggcg ctgtacctga tctttcgtaa taaaaaagag
    59461 attacccagc atttgctcaa cttcgcggag cattcgctgg cctttttcag cctgtttatc
    59521 cgcgcctttg cgctggtgtg gcactggctg gcaagcgcct attttatcgt gctgtttttc
    59581 ttttcgttgt tcgatccggg caacagcctg aaatttatga tgggtgcaac ggtgcgtagc
    59641 ctggcgatta ttggtatcgc agcatttgtt tccggtatgt tttcccgctg gctggcgaaa
    59701 accatcaccc tctcgccaca tactcagcga aattatccgg agctgcaaaa acggctgaac
    59761 ggctggcttt cggcggcatt gaaaacggcg cgtattctga ccgtctgcgt ggcggtaatg
    59821 ctgctgttga gcgcatgggg attgttcgat ttctggaact ggctgcaaaa cggtgcgggg
    59881 cagaaaaccg tagatatcct gatccgtatc gcactcattc ttttcttctc ggcggttggc
    59941 tggacggtgc tcgccagttt gatcgaaaac cggctggctt cggatattca tggccgcccg
    60001 ctacccagcg cccgcacgcg taccctgctt acgctgtttc gtaacgcgct ggcggtgatt
    60061 atcagtacca tcaccatcat gattgtgttg tcggaaatcg gcgtcaatat cgcgccattg
    60121 ctggcaggtg ccggggcatt aggtctggct atctcgtttg gttcgcaaac gctggtgaaa
    60181 gatattatca ccggggtatt tattcagttt gaaaacggta tgaacactgg agatttggtg
    60241 actatcgggc cgttgaccgg cactgtggaa cggatgtcga ttcgctccgt gggcgtgcgt
    60301 caggataccg gggcgtatca catcattccg tggtcttcta taactacctt tgctaacttc
    60361 gtccgcggca ttggttcggt ggtggcaaat tacgatgttg atcgccatga agatgctgat
    60421 aaagccaatc aggcactgaa agatgcggta gcggaattga tggaaaacga agaaattcgc
    60481 gggctgatta ttggtgaacc gaattttgcc gggattgtcg gcttaagcaa taccgcgttt
    60541 acactgcgtg tttcgttcac cacgctgcca ctcaaacagt ggacggtccg ctttgccctc
    60601 gacagccagg tgaaaaaaca tttcgacctg gcgggcgttc gcgcgccagt gcagacttat
    60661 caggtgctgc ctgctccggg cgcgaccccg gctgaaccgt tgccgccggg ggaaccaacg
    60721 ctttaacgct ggcgattgac aaaacggcgg cgctgctcgt cgttcataaa ggtccaggca
    60781 ataaagcgac tctgcttttg cccctgggcc atctcttttt taaccacctt caccgcgccc
    60841 acgtccgtca gggcacgata caacggcggt aagttttcac cacgagatac cagcgaggta
    60901 aaccacatca cctgcttcgc gaagcctttg ctctcttcaa tcatcttttt aataaaagcg
    60961 acttcaccgc cttcacacca caactcctgt tgctgaccac caaaattcag tgcatcgtct
    61021 ttgtttagcc ccaggttacg gcgtttacgt tcactacctg cccgtgccgc agcggcggaa
    61081 tcgtggaatg gcgggttaca caaggtcgcg tcgtattgct cgtttttatg gatgatgccg
    61141 ttaaaaatcg ccccactctc tttttgccga cgcagacgaa tggcgcggtt aagccccgga
    61201 ttagcactga tgattgcctg cgcactgctt aacgcctggc tgctggtttc actaccagta
    61261 aaacgccagc catattcatg tacgccaatc agcggataaa tacagttcgc accaacgccg
    61321 atatccagaa tgctggcatt agctggaatt gatcctgttg cttctgccag taaatcggca
    61381 aggtgatgaa tataatccgc ccggcccggt actggtgggc agagaaaacc gtcggggata
    61441 tcccagttcg ctacggcgta aaaatgggcc agcaacgcct tattgagcgc cttcaccgcc
    61501 agcggattgg caaagtctac gctttgctcc ccggcgggtg taagcgtgag gaattgcctg
    61561 agttcaggat tgacctgaca aagcgtggcg agatcgtagc ggctgtgatg acggttgcgc
    61621 ggatgcaacc ccggtttctg ggcggacata gcattctcct ttaagcagcg gcgtaagata
    61681 cccgcataac gcgacagggt aaatatctgg ctgcgtttat catttctata aaccttcaca
    61741 tggctatggt ttatggcaat tcatcataaa agtcagcatt atgcatatca ttgatttgtc
    61801 ttgttttgta aaaatatatc gttcaaaaaa caagcacatc tctgtcaatt ttttgcgtca
    61861 ttttcatcgc ccaggcgacc tacacttatc aggcactacc cgttgtattt atgaggatgt
    61921 cattatgaaa aagtgcctca cactactgat tgccaccgtc ctgagcggaa tctctctcac
    61981 ggcttatgcc gcgcaaccga tgagtaacct ggacagcggt cagctacggc ccgccggtac
    62041 cgtttcggca actggcgcat caaacctaag cgatctggag gataaactgg cagaaaaagc
    62101 gcgcgaacaa ggcgcgaaag gttatgtcat taattccgca ggcggaaatg accagatgtt
    62161 cggtactgca atcatctaca aataacccca ccaacgtaac tgcattcgcc tctggatgca
    62221 gttttcgtcc gatttgtaag caaaaaacat caaatatgaa cgcaatgtaa ataaatgtat
    62281 ttctttttcg cgcaatgggt gatagaaaat cgcgctaagt gataatgctt atcaaaatta
    62341 ttatcacttg cacgaacgct atcacgagat taacagtggc atcgcatccg cagagatgct
    62401 ttctcgtggc agtgaaaatt tcaacatata agaaaaagtc acctgcaaaa tggaaaacaa
    62461 tcgcaatttc cctgccagac aatttcattc gctcacgttc tttgccggtc tttgtattgg
    62521 catcacgcct gtggctcagg ctctcgccgc cgaagggcaa actaacgcgg atgacacgct
    62581 ggttgtcgaa gcatcaacgc cttcgcttta tgcgccacaa caatctgccg atccgaaatt
    62641 ctcgcgtccg gtagcggata ctacccgcac gatgacggtg atttctgaac aagtgattaa
    62701 agatcagggc gcaaccaacc ttaccgacgc gctcaaaaac gtccccggcg tgggtgcgtt
    62761 ttttgcgggt gagaacggta actccaccac tggcgacgcc atttatatgc gcggtgccga
    62821 tacttctaac agtatttata ttgatggcat tcgcgatatc ggcagcgtct cgcgcgacac
    62881 cttcaatacc gagcaggtcg aagtaattaa agggccgtcc ggcaccgact acgggcgcag
    62941 cgcgccgacg ggctcgatca atatgatcag caagcagccg cgcaatgatt cgggcattga
    63001 cgcctccgcg agtattggca gcgcctggtt ccgccgcggc acgctggacg tcaatcaggt
    63061 cattggtgat accactgcgg tgcgcctgaa cgtgatgggc gaaaaaacgc acgatgccgg
    63121 acgcgacaaa gtcaaaaatg agcgttacgg cgtcgcccct tctgtcgctt ttggccttgg
    63181 tacagcgaat cgtttgtatc ttaattatct gcatgtcacc cagcacaaca cgccagacgg
    63241 cggcattccg accatcggtt taccgggtta ttctgcccca tctgcgggaa cggcggccct
    63301 gaatcattcc ggaaaagttg atacgcataa cttttacggc acggattccg attacgacga
    63361 ttcgaccacc gacaccgcta ccatgcgttt tgagcacgac atcaacgata acaccaccat
    63421 tcgcaatact acccgttggt cgcgcgtgaa gcaggattac ctgatgacgg cgattatggg
    63481 cggggcgtcg aatattaccc agcccaccag cgatgtgaat agctggacct ggtcacgcac
    63541 ggcgaatact aaagatgtga gtaataaaat tctcaccaac cagaccaacc tgacctcgac
    63601 gttctatacc ggttctatcg gtcatgatgt cagtaccggc gtggaattta cccgtgaaac
    63661 gcagactaac tacggcgtta atccggtgac gttacctgcg gtaaatattt atcatcctga
    63721 cagcagcatt catcccggcg gcctgacgcg caacggcgca aacgccaatg gtcagacgga
    63781 taccttcgca atttacgcct tcgatacgct gcaaatcacc cgtgattttg agctgaacgg
    63841 cgggatccgt ctggataatt atcatactga atatgacagt gccaccgcct gcggcggcag
    63901 cggacgcggt gccatcacct gccctgctgg cgtggcaaaa ggttctccgg tcaccaccgt
    63961 cgataccgcc aagtcgggca atctggtgaa ctggaaagcc ggggcgctgt atcacctgac
    64021 ggaaaacggc aatgtctata ttaactatgc cgtttcccag cagccgccgg gcggcaacaa
    64081 cttcgccctt gcgcagtctg gcagcggtaa cagtgccaac cgcaccgatt ttaaaccgca
    64141 aaaagccaac accagcgaga ttggcaccaa atggcaggtt ctggataaac gcctgttgct
    64201 caccgccgcg ctgttccgta ctgatatcga aaatgaagtt gagcaaaatg atgacggaac
    64261 ttactcgcaa tacggtaaga aacgcgtcga aggctatgag atatccgtgg ccgggaatat
    64321 cactcccgcg tggcaggtga ttggcggcta tacccagcaa aaagcaacca tcaaaaacgg
    64381 caaagatgtt gcccaagatg gttcctcatc gctgccctat acgccggagc acgcctttac
    64441 cttatggagc caatatcagg caaccgatga tatttccgtt ggtgcgggcg cacggtatat
    64501 cggcagtatg cataaaggtt ctgacggcgc ggtgggaacg ccagcgttta ccgaaggtta
    64561 ttgggtcgcc gacgctaaac tggggtatcg ggttaatcgc aatctcgact tccagctaaa
    64621 cgtctacaac ctgtttgata ccgattacgt cgcctcaatc aacaagagcg gctaccgtta
    64681 tcacccgggc gagccaagaa ccttcttgct cacggccaat atgcatttct gattcagatg
    64741 tggggcgcag gccccatttt ttggagaact tgtatgatgt accacattcc cggcgtgcta
    64801 tcgccaaagg acgtcgcccg gtttcgcgaa caactggaac aagccgaatg ggtggatgga
    64861 cgcgtcacca ccggcgcaca aggtgcgcaa gttaagaaca atcaacaggt agacacccgc
    64921 agcacgttat acgccgccct gcaaaatgag gtgctgaacg cggttaatca acatgctttg
    64981 ttctttgccg cggccttgcc gcgtaccctt tccacgccgc tgtttaatcg ctatcagaac
    65041 aatgaaacct atggtttcca tgtggatggc gcagtacgca gccatccaca aaacggctgg
    65101 atgcgcactg acctttctgc cacgctgttt ttaagcgatc cagaaagcta cgacggcggc
    65161 gaactggtcg ttaatgacac cttcgggcaa catcgggtaa aactcccggc aggcgatctg
    65221 gtgttgtacc cttccagcag cctgcactgc gtgacacccg taacccgtgg cgtacgggtg
    65281 gcatcattta tgtggatcca gtcgatgatc cgcgatgata aaaagcgcgc catgctgttc
    65341 gaactggaca ccaatattca gtcgctgaaa agccgccatg gcgaaagtga agagatcctg
    65401 tcgctgctca atctttatca taatctgctg cgggaatggt cggagatctg acgcttgaac
    65461 tgcccgagtt cgtccctata ttagctacac ttagctgtac aagcattgat atggggagga
    65521 cgatatggca tccggttggg ctaatgatga cgccgtcaac gaacagatca acagtacaat
    65581 tgaagatgcg attgcccgcg ctcggggtga aattccgcat ggcgaaagcc tgtatgaatg
    65641 tgaagagtgc ggtgccccta tcccgcaggc ccgtcgggaa gccattcctg gcgtgcgctt
    65701 atgcattcat tgtcagcagg agaaagattt acaaaaacca gcttatacag gatataatcg
    65761 cagaggttcg aaagacagcc agttacgtta actacaactg gcgggatgta tagcgagtat
    65821 aatttgtatt ttgcgtggca ttccgtgcct ttaacgctac cgtgactgcc acgcggtata
    65881 aaacaagtcc ataagtacaa caaataaatg gtttatcagt atgttagata tcaatcaatt
    65941 tatttgaaca aggcggtcaa ttctcttcga ttttatctct cgtaaaaaaa cgtgatactc
    66001 atcacatcga cgaaacaacg tcacttatac aaaaatcacc tgcgagagat taattatgaa
    66061 aactatcaat actgttgttg ctgctatggc tctttcaact ctgtcatttg gcgtgttcgc
    66121 ggcggaaccg gtaacggcat cccaggcaca gaacatgaat aaaatcggcg tggtttctgc
    66181 cgatggcgca tccaccctcg atgccctgga agcgaaactg gctgagaaag ccgcggcggc
    66241 cggtgccagt ggatacagca tcacttctgc caccaacaac aataaattaa gcggtactgc
    66301 ggtaatttat aagtaattcg tatgctagat caggcggtta cgctacgttc agcacaagta
    66361 tttccctgtc tgtttgccga cagacgcata tgctctaacc ctcattgatc ctatgttacc
    66421 cttgtttgcc cgtccgccac tggacgggct tttttttagc tggctaactg ctgacagaaa
    66481 gcctgcaacg tctcttccgg cataccaatc tgccgcgctg catcacaaat ggcctgccag
    66541 cttcccgcat ccagtggaat cccctgctcc tgccgttcgc gacgcgtgtt cacttcccac
    66601 tcgcccggta gcaaaatcgg cttatcgtca tcatgcggcg aggctttcac ccactcggca
    66661 aaggcttcgg tctgtgcact acaatccggc gcgccgaaca gttccgggtt gatgatgatg
    66721 gtagtcatgc agttaagaat ggcatcggga ctggtttgta acgtttcctg atgcgtcgtt
    66781 ttaccgccgg aaagcgcccc accaagaatt tcacacatcg ctgcaagggc gtagccttta
    66841 tgttcggcaa aggtcaacag cgaacccaac ggcgactcct gcattaccgc cggattggtc
    66901 gtcggcacgc cgttaacgtc aatcaggcaa cctggcggca cggggacgcc tttatgccag
    66961 gcgacgcggg ttttgccaaa tgcgatggcg ctggtggcgt aatcaagcaa cagcgggaaa
    67021 ttatctctac gagggaaaac cacacagaac ggattggtgc caaagcggct gtcgcgaccg
    67081 tggaacggcg cgaccattgg aataccgacc acgctaacaa agtggatgga gacaaacccc
    67141 gccgctgcac actgctccgc ccagtaaccg atacggccga tatgatgcga gttatgtagc
    67201 gccacggcag caataccgtg ctgatgcgct ttctcaatcc ccaacgccat cgcttcgtgt
    67261 gccgcgacct gaccaaatgc gcgatcgcca tcgagcgtga ccgccgcccc cgcctcttta
    67321 acgattttgg catgatggtt aatttgcaga tgcccctgac tccaggagcg cacatagctt
    67381 gggatcatgc caataccatg tgaatcatgc cctgccaggt ttgccgcgat taaatgatcg
    67441 gcaactaatt tcgcttcttg ttcctcgcta cccatctgac gaaatacagc ctgaataaaa
    67501 ctgtgcaacg tctgagcatc aaagcgatga ccactttcca tggttaactc ctgtttatgt
    67561 tatgtgtttg ttgttttttt atgctgcacg ccgggcgcgg gaaggtcaat aaagatgcag
    67621 gaatttcata ttgcggtggg gtaaaagccg gatgacatgg ctcatccggc tgagaaaaga
    67681 attagaatgc ctgattaacg cgcgccaggc cgtcgctgat agttgccgct tcacccgtag
    67741 ccaccaggca gcaagccatc tggattttca gcgattcggg aatcggttcg ctgccagcca
    67801 ggcaacgctc aatccactgc gccgtggttt ccggatcttt tgcttgtggc agtaactcgc
    67861 taccagcagt gtcctgtttt tcatacagca cccgcatccc ttcacggtca atgagattga
    67921 tctgcgggca gcgctgcgga ttagcataca cttcaccttc agtaccatgc attagtagcg
    67981 cccgcccgcc gatatcgcta aagaacttcg cgacgcgtcc aatgtattcc ggatgcgaaa
    68041 cgctggaaag acgcagtgcc tcaccttcgg caaatggcgt cgccagtttc gccagggtat
    68101 gtgcactgtt acgcacgccc atccgccagc gcatcgccag ttgtttttcc agcggcgggc
    68161 aaaacgcgcc gacaggcata aacaccggtt gatgttcgtc gagcttcgcc tgcgcctgcc
    68221 cgccgtgcaa cgttggcgta atacccatca gttcgaaaat ggtttctgtc agcacgcggg
    68281 ttggatcttc gctaaccccg tgaaccacca caggaaaacc gagtttgtgc aggagaatcg
    68341 ccaacaacgg cgtcaggttg gcctgtttac gcgcgccgtt gtaactgggg atgacaatcg
    68401 gcatcggctt gtctgcaggc ggcgtcagct tgatggtgtg attttgcatg gcttcgtaaa
    68461 agccgagcat ctctgcttcc ccttcccctt tgatacgcag cgcaatcaat acgccgccca
    68521 actcaaggtc agggacttca ccattgagca tatgggcata cagaccgcgc gcagtatccc
    68581 ggtctaaatc gcgcgcgtgg tttttcccgc gcccgatctc tttaatgatt ttgcgatagt
    68641 ccatttacga ctccttacct gactcacatc attaacgccg ccgacggcgt ggggatttcg
    68701 ttttttcttt ctttttaact ataccttcag ggacttccgg ttgctctatc ggaaataccg
    68761 gtaatgcatc cagtagtcgc ttgccataat ttttggtcag caagcgtttg tcgtagataa
    68821 ccacttcccc ccagcaaccg tggcttcgaa tcagtcgccc aacctgctga atcaggttaa
    68881 acgaagcgct cggcaggctt tgcacctcaa acggatagcg gttgaggctt ttcagccatt
    68941 caccttcggt gatcaccacc ggactgtcga tgggcggaaa agcgattttg tggatatgca
    69001 cctggctgag cagatcgcct ttcagatcaa gcccttcggc aaatgactgt aagcccacca
    69061 gcacgctgcg ctcaccgttg gcgacgcgtt tgcggtgcag ttcaactaaa cggtaacgcg
    69121 gctgatcgcc ctgcaccagc aacatcagac gtaaatccgt cacatagtcg agaaagcgct
    69181 gcatcgcccg tccgctggca aacagtacca acataccgag atgttttttg ctctccacct
    69241 gcttacggaa aaaggccgcc atttcggcaa tatgctgctc ttcgttgtcg agagaaggct
    69301 caacgcgcat ccggggaata acaattttgc cctgttcgca gtggttgaag ggggaatcca
    69361 gcgccacaaa acggtcgccc gctttctctt tcagaccact catctcctgc aaacgcgaaa
    69421 aactgttcag cgaacgcaag gttgcggagg tgacaataat gtgcggaata ctgcgccaca
    69481 gcagcctttc cagctgatcg ctgacacgaa tacccacaca gtgaaaccag agatgcagct
    69541 gcccttcgcg ctcttcccgc gtcgcccatt tggtcaccgg cgcaccggaa gattgcgcca
    69601 gagacgccag ccgccagagt ttgctttgcg cctcgaacat ccccaacgcg cgattcatct
    69661 gcaaaatcaa ccgatgcaga cgtacaatgt catggctgcc ggttttctca cttaaatcgt
    69721 taagaaataa ctccgccagg ccacgcagca tctcggtgag ttttgccagc cgctggcaga
    69781 tctcctgcac ttcatcaggc agttcgccca tcgcaaaacg gtgctctgcc tcctgcccgg
    69841 caggcatgta gagattgaga atgttgttta acgaggcgat aagctcatac agctcttcac
    69901 aatgcgcatt caaacgttca gggatcgcca gcggtgggat ggtcttcggg cgaaactgct
    69961 ccatgcaggt agcgaccagt ttcgtgaaca agtccaactg tagtcgatac cagggcgcgg
    70021 tgatttcggc gctcatctcc agcgcatccc gcgccacatc tggcaggtga tgaccttcgt
    70081 ccagcaccag cagtaaattt ttcgggtcag gcaatacggc ttcgctttcc atcgccgcca
    70141 tcaccagcgc atggtttgcc accaccactt ccgcttcctg aatttcccga cgagcaacaa
    70201 aaaacgggca ttcgcgatag tagtaacagt tgcggttgag gcagctggct ttgtcggtac
    70261 tcaaacgacg ccagagatca tcatctatag cgatatcagt atgatcgcgc aggccatccc
    70321 atttataagt gtcgagatcg cccttcagct tcgcacaacg tttttgctct tcctgattgt
    70381 tcggtgtcag ctcgtcgtca agaaacgcca gcagatcctg ttgcgtgggt tcagtactgg
    70441 cgagcgccgt cagattacgc gggcaaacgt agcgcccacg cccaaaagca gcagtgaatt
    70501 taagatcggg aatgatcttt ttcagcagcg gtaaatcttt gctgtagatc tgatcctgca
    70561 atgccacgtt ggcggtactt accaccagcg ttttttgctc ttcgcgggca atggcgatgc
    70621 cggggatcaa ataggagagc gttttcccaa cgccggtggg tgcttcaatc gccagatgcc
    70681 gcccttcttc tccggccagc gttttggcga cgtccgcaat catctgccgc tgcggcgcac
    70741 ggggaataaa gtcggggatc tgttcctgaa gcgccttata ccaggcggca atttgcgctt
    70801 taagcgcggc ggttaatgcc atgagaaaac ctgaaatact gtataaacag ccaatattgt
    70861 ggcatttttc ggttttcagg ggtaatggtt tttctgtttc tggaaagcgg ctcgcaataa
    70921 ccatcaacat aatgcggttt aatgcccgtt cgagcacaaa ggatccaaca cgtcatgcaa
    70981 gacaccatca taaatttcta cagcaccggc gatgactacg gtgatttttc taactttgcc
    71041 gcctggccca tcaaggttga cgggaaaacc tggcccacct cagaacacta ttttcaggca
    71101 caaaaattcc ttgatgaaaa ataccgcgaa gagatccgtc gggtttcttc ccctatggtc
    71161 gccgcacgca tggggcgcga tcgttctaag cctctgcgta aaaactggga gtcggtcaaa
    71221 gaacaggtga tgcgaaaagc acttcgcgct aaattcgaac agcatgcaga actgcgtgcg
    71281 ctcttgctgg caaccgcgcc cgcaaaactg gttgagcata cggaaaatga tgcttactgg
    71341 ggagacggtg gtaatggtaa gggcaagaat cgactgggct accttttaat ggagttgcgc
    71401 gaacaattgg ctatagagaa gtaacgtctc gggtggctta tgggaggtaa aacagagaaa
    71461 ttttttcccg tgttctcaaa ttgctgacaa gtgcttgttg tgaaatgccg gatgcggcgt
    71521 aaacgcctta tccggcctac aaaagcatgc aaattcaata tattgcagag ttcacgtagg
    71581 cctgataagc gcagcgcatc aggcagtttt gcgtttgttc atcagcctga tgccgggcat
    71641 cgcccggcat caaaagatta ctgcgcagcg gcaggtttac gcggacggcg gcgacgttgt
    71701 tgttcgcctg ccggtttggc atcgccggga cgacgagacg gtttttctgc gggcttcgcg
    71761 ttaccagact tcgcaccact ttccgcacgg cgtggttgct gttgaccgcg accaccgcct
    71821 tgtccacgac cgccgccacg ttgctggcga ccgttctgta tcggttcggc tttgattgac
    71881 gggtccggct cataccccgg aatcgcaatg cgcgggatct cttttttcag cagtttttcg
    71941 atatcacgca gcagtttgtg ttcatcaaca cacaccagcg acaacgcttc accggtagca
    72001 gccgcacgac cggtacgccc gatacggtgg acataatctt ccggtacgtt tggcagttca
    72061 tagttgacca cgtgcggcag ctcttcaata tccaggccgc gcgcagcgat gtcagttgcc
    72121 accagtacac gaatatcgcc cgatttaaaa tcggccagcg cacgagtacg cgcaccttgc
    72181 gatttattac cgtggatcgc cgcactacgg atgccatctt tattgagctg ttcagcgaga
    72241 tggttagcgc catgtttggt acgggtaaac accagcacct gctgccagtt ccctttccca
    72301 atcatgtgcg acagcaattc gcgtttgcgt ttcttatcga caaagtgaac atgctgggtc
    72361 acctgatcag acgcggtatt gcggcgtgcc acttcgattt ccagcgggtt gtgcaacagt
    72421 ttttccgcca gagctttaat atcgtcagag aaggtcgcgg agaacaacag gttctggcgc
    72481 ttcgctggca gttttgttaa cacgcgacgg atatcgtgga taaagcccat gtcgagcatg
    72541 cggtcagctt catcgaggac gaggatttca acctgatcca gcttcaccgc attctgatgt
    72601 tccaggtcca gcagacgtcc cggcgttgcc accagcacat caacgccgcc gcgcaacttc
    72661 atcatctgcg ggttaatgct gacaccgcca aacaccacca gcgaacggat attcaggtat
    72721 ttgctgtaat cacggacgtt ttcgccaatc tgcgccgcca gttcacgggt tggggtaaga
    72781 atgagcgcac gtaccggacg acgccctttg gcgtgcggct ggcgagtgat caggtgttgc
    72841 aacagcggca gcgtaaagcc cgctgttttg ccggtaccgg tctgggcgct ggccatcagg
    72901 tcgcggcctt ccagcaccgc agggatcgcc tgctgctgaa taggggtggg ttcacggtaa
    72961 ccctgctcgg caacggcgcg caggatatca gggcttaaac ccaaagaatc gaaagacata
    73021 actactccga accgccccga ccgttaccgg tgtagttttc agggagatac tgaaaaggaa
    73081 aatgacaaaa accacaatgt catgagggag cggagtgtag cagtttttgt gacgcagcgc
    73141 ataaattatc cctgtgactg gcgtagctaa aattcttagc catactggac aactccccta
    73201 tggagtcata atcttaatca atcatttgat taagaatgga ctgtgcgatg aataatcctg
    73261 ccatgacaat caagggtgaa caggcgaaaa aacagctgat tgctgccgca ctggcgcagt
    73321 ttggtgaata tggaatgaac gccaccaccc gcgagatagc ctcccaggcc gggcagaata
    73381 tcgctgccat cacctactac ttcggttcga aagaggattt gtacctcgcc tgcgcccagt
    73441 ggattgccga ttttattggc gagcagttcc gtccgcacgc cgaagaagcc gaacgtttgt
    73501 tcgcgcaacc acagcctgat cgcgcagcta tccgtgaact gatccttcgc gcctgcagga
    73561 acatgattaa gctgctcacc caggatgaca ccgtcaacct cagcaagttt atctcccgtg
    73621 agcaactctc tcctacggca gcctaccacc tggtgcatga acaggtgatt agcccgctac
    73681 acagccacct tacacgcctg attgccgcct ggaccggctg cgacgccaac gacacccgca
    73741 tgatcctcca tacccatgcg ttgattggtg agattctggc gtttcgtctt ggcaaagaaa
    73801 ctattttgtt acgtaccggc tggaccgcgt tcgatgaaga aaagaccgaa ctgatcaacc
    73861 agacggtgac ctgtcatatc gacctgattt tgcaaggatt atcgcaaagg agtttgtagt
    73921 gatgaaaaaa cctgtcgtga tcggactggc ggtagtggta cttgccgccg tggttgccgg
    73981 aggctactgg tggtatcaaa gccgccagga taacggcctg acgctgtatg gcaacgtgga
    74041 tattcgtacg gtgaatctta gtttccgtgt tggggggcgc gttgagtcgc tggcggtgga
    74101 cgaaggtgat gcggtcaaag cgggccaggt gctgggcgaa ctggatcaca agccgtatga
    74161 gattgccctg atgcaggcga aagcgggcgt ttcggtggct caggcgcagt atgacctgat
    74221 gcttgccggg tatcgagatg aagaaatcgc tcaggccgcc gcagcggtga aacaggcgca
    74281 agctgcctat gactatgcgc agaacttcta taaccgccag caaggactgt ggaaaagccg
    74341 caccatttcg gcaaatgacc tggaaaatgc ccgctcctcg cgcgaccagg cgcaggccac
    74401 gctgaaatca gcgcaggata aattgcgtca gtaccgttcc ggtaaccgcg aacaggacat
    74461 cgcccaggcg aaagccagcc tcgaacaagc acaggcgcaa ctggcgcagg cggagctgaa
    74521 tttgcaggac tcaacgttga tagcaccgtc tgatggcacg ctgttaacgc gcgcggtaga
    74581 gcccggcacg gtgcttaatg aaggtggtac ggtatttacc gtctcgctga cgcgtccggt
    74641 gtgggtacgc gcctatgttg atgaacgtaa tcttgaccag gcccagccgg ggcgcaaagt
    74701 gttgctttat accgatggtc gcccggacaa gccgtatcac gggcagattg gtttcgtttc
    74761 gccgactgct gaatttaccc cgaaaaccgt cgaaacaccg gatctgcgta ccgatctcgt
    74821 ctatcgtctg cgtattgtgg tgaccgacgc cgatgatgcg ttacgccagg gaatgccggt
    74881 aacggtgcaa ttcggtgacg aggcaggaca tgaatgatgc cgttatcacg ctgaacggcc
    74941 tggaaaaacg ctttccgggc atggacaagc ccgccgtcgc accgctcgac tgcaccattc
    75001 acgccggtta tgtgacgggg ctggttgggc cggacggtgc gggcaaaacc acgctgatgc
    75061 ggatgctggc gggattactg aaacccgaca gcggcagtgc cacggtgatt ggctttgatc
    75121 cgatcaaaaa tgacgctgcg ctgcacgccg tgctcggcta tatgccgcag aaattcggcc
    75181 tgtatgaaga tctgacggtg atggagaacc tcaatctgta cgcggatttg cgcagcgtca
    75241 ccggtgaagc acggaagcag acttttgctc gcctgctgga gtttacgtct cttggcccgt
    75301 ttaccggacg cctggcgggc aagctctccg gtgggatgaa acaaaaactc ggcctggcct
    75361 gtaccctggt gggcgaaccg aaagtgttgc tgctcgatga acccggcgtc ggcgttgacc
    75421 ctatctcacg gcgcgaactg tggcagatgg tgcatgagct ggcgggcgaa gggatgttaa
    75481 tcctctggag tacctcgtat ctcgacgaag ccgagcagtg ccgtgacgtg ttactgatga
    75541 acgaaggcga gttgctgtat cagggggaac caaaagccct gactcaaact atggccggac
    75601 gcagctttct gatgaccagc ccgcacgagg gcaaccgcaa actgttgcaa cgggcattga
    75661 aactgccgca ggtcagcgac ggcatgattc aggggaaatc ggtacgcctg atcctcaaaa
    75721 aagaggccac accagacgat attcgccatg ccgacgggat gccggaaatc aacatcaacg
    75781 aaactacgcc gcgttttgaa gatgcgttta ttgatttgct gggcggtgcc ggaacctcgg
    75841 aatcgccgct gggtgcaata ttgcatacgg tagaaggcac acccggtgag acggtgatcg
    75901 aagcgaaaga actgaccaaa aaatttggcg attttgccgc caccgatcac gtcaactttg
    75961 ccgtcaaacg cggtgaaatc tttggtttgc tggggccaaa cggcgcgggt aaatcgacca
    76021 cctttaagat gatgtgcggt ttgctggtac cgacctctgg tcaggcgctg gtgctgggca
    76081 tggatctgaa agagagttcc ggtaaagcgc gccagcatct cggctatatg gcgcaaaaat
    76141 tttcgctcta cggcaacctg acggtcgaac agaatttacg ctttttctct ggtgtgtatg
    76201 gcttacgcgg tcgggcgcag aacgaaaaaa tctcccgtat gagcgaggca tttggcctga
    76261 aaagtattgc ctcacacgcc accgatgaac tgccattagg ttttaaacag cggctggcac
    76321 tggcctgctc gctgatgcat gaaccggaca ttctgtttct cgacgaaccg acgtccggcg
    76381 ttgatcccct cacccgccgc gaattctggc tgcacatcaa tagcatggta gagaaaggcg
    76441 tcacggtgat ggttaccacc cactttatgg atgaagcgga atattgcgac cgcattggcc
    76501 tggtgtatcg cgggaagctg attgccagcg gcacgccgga cgatttgaaa gcacagtcgg
    76561 ccaacgatga gcaacccgat cccaccatgg agcaggcctt tattcagttg atccacgact
    76621 gggataagga gcatggcaat gagtaatccg atcctgtcct ggcgtcgcgt gcgggcactg
    76681 tgcgtcaaag agacgcggca gatcgttcgc gatccgagta gctggctgat tgcggtggtg
    76741 atcccgctgc tactgctgtt tatttttggt tacggcatta acctcgactc cagcaagctg
    76801 cgggtcggga ttttactgga acagcgtagc gaagcggcgc tggatttcac ccacaccatg
    76861 accggttcgc cctacatcga cgccaccatc agcgataacc gtcaggaact gatcgccaaa
    76921 atgcaggcgg ggaaaattcg cggtctggtg gttattccgg tggatttcgc cgaacagatg
    76981 gagcgcgcca acgccattgc accgattcag gtgatcaccg acggcagtga gccgaatacc
    77041 gctaactttg tgcaggggta tgtcgaaggg atctggcaga tctggcaaat gcagcgcgcg
    77101 gaggataacg ggcagacttt tgaaccgctt attgatgtac aaacccgcta ctggtttaac
    77161 ccggcggcga taagccagca ctttattatc cccggtgcgg tgactattat catgacggtc
    77221 atcggtgcga ttctcacctc gctggtggtg gcgcgagaat gggaacgcgg caccatggag
    77281 gctttgctct ctacggagat tacccgcacg gagctgctgc tgtgtaagct gatcccttat
    77341 tactttctcg ggatgctggc gatgttgctg tgtatgctgg tgtcggtgtt tattctcggc
    77401 gtgccgtatc gcgggtcgct gctgattctg ttttttatct ccagcctgtt tttactcagt
    77461 accctgggga tggggctact gatttccacg attacccgca accagttcaa tgccgctcag
    77521 gtcgccctga acgccgcgtt cctgccgtcg attatgcttt ccggctttat ttttcagatc
    77581 gacagtatgc ccgcggtgat ccgcgcggtg acgtacatta ttcccgctcg ttatttcgtc
    77641 agcaccctgc aaagcctgtt cctcgccggg aatattccag tggtgctggt ggtaaacgtg
    77701 ctgtttttga tcgcttcggc ggtgatgttt atcggcctga cgtggctgaa aaccaaacgt
    77761 cggctggatt agggagaaga gcatgtttca tcgcttatgg acgttaatcc gcaaagagtt
    77821 gcagtcgctg ctgcgcgaac cgcaaacccg tgcgattctt attttacccg tgctgattca
    77881 ggtgatcctg ttcccgttcg ccgccacgct ggaagtgact aacgccacca tcgccatcta
    77941 cgatgaagat aacggcgagc attcggtgga gctgacccaa cgttttgccc gcgccagcgc
    78001 ctttacccat gtgctgctgc tgaaaagccc gcaggagatc cgcccgacca tcgacacaca
    78061 aaaggcgtta ctcctggtgc gtttcccggc tgacttctcg cgcaaactgg ataccttcca
    78121 gaccgcgccg ttacagttga tcctagacgg gcgtaactcc aacagtgcgc aaattgccgc
    78181 caactacctg caacagatcg tcaaaaatta tcagcaggag ctgctggaag gaaaaccgaa
    78241 acccaacaac agcgagctgg tggtacgcaa ctggtataac ccgaatctcg actacaaatg
    78301 gtttgtggtg ccgtcgctga tcgccatgat caccactatc ggcgtaatga tcgtcacttc
    78361 actttccgtc gcccgcgaac gtgaacaagg tacgctcgat cagttactgg tttcgccgct
    78421 caccacctgg cagatattca tcggcaaggc cgtaccggca ttaattgtcg ccaccttcca
    78481 ggccaccatt gtgctggcga ttggtatctg ggcgtatcaa atccccttcg ccggatcgct
    78541 ggcgctgttc tactttacga tggtgattta cggtttatcg ctggtaggct tcggtctgtt
    78601 gatttcatca ctctgctcga cacaacagca ggcgtttatc ggcgtgtttg tctttatgat
    78661 gcccgccatt ctcctttccg gttacgtttc gccggtggaa aacatgccag tgtggctgca
    78721 aaatctgacg tggattaacc ctattcgcca ctttacggac attaccaagc agatttattt
    78781 gaaggatgcg agtctggata ttgtgtggaa tagtttgtgg ccgctactgg tgataacggc
    78841 cacgacaggg tcagcggcgt acgcgatgtt tagacgtaag gtgatgtaac ttcttatctt
    78901 tcgccagcaa agacactacc gccgggccag caaggattgc cagccctgca attgccagca
    78961 aaaagttgtt ttccagtacg cgggacaaca gccacagcac aatcagcgct gcaccaaaat
    79021 accaggtcgt ggtcagctct tccagcacgt ctgccacctc acgccagcgt tgctcggggt
    79081 ggcgctgaaa caccagcatc atcactaccg tgacacaata cagtgcgcat aatcccacgc
    79141 cgacgtgaac cagagtctta ctcatccagc ccaccaccag cagcgccact accagtaaat
    79201 gcaacataat ctgccagcaa cttagacccg ttgcgacacg aacacgttgt tgccacttca
    79261 tggcttctct cctgaagaat ttatctctac ttattcagag taccgaactt tacggaaaat
    79321 tccgtaagac cgcacctttt tgtgacgccg actacactat ttcaatgaga taagaggcaa
    79381 agacaggaaa attatgcccg atcaaacaca acaattttcg ttcaaggtgc tcaccatcaa
    79441 tattcacaaa ggctttaccg cgtttaaccg acgcttcatt ttgccggaac ttcgcgacgc
    79501 cgtgcgtacc gtcagtgccg atattgtttg cctgcaggaa gtgatgggcg cgcacgaagt
    79561 tcatccgctg catgtggaaa actggcccga tacctcgcac tacgagtttc tcgccgacac
    79621 catgtggagc gatttcgcct acggtcgcaa tgccgtatac ccggaaggac atcacggtaa
    79681 tgcggttctt tcacgttatc ccattgaaca ttatgagaat cgtgatgttt cggtcgatgg
    79741 tgcggaaaag cgcggcgtgc tctactgccg cattgtgccg ccgatgaccg ggaaagcgat
    79801 tcatgtgatg tgcgtacatc tgggcctgcg tgaggcgcac cgtcaggcgc agcttgcgat
    79861 gctcgccgaa tgggtgaatg agctaccgga cggcgaaccg gtattggtgg cgggtgattt
    79921 caatgactgg cggcaaaaag ctaatcatcc gttaaaagtg caggccggac tggatgagat
    79981 ttttacccgc gcccacggac gcccggcgcg cacgtttccg gtgcaatttc ctctactacg
    80041 actggacagg atctacgtca aaaatgccag cgccagcgcg ccaaccgcgt tgccgctgcg
    80101 gacatggcga cacctttctg atcatgcccc tttaagtgcg gagattcatt tatgaaatgt
    80161 agctggcgcg aaggcaataa gatccagttg ctggaaaacg gcgagcaata ttatcccgcg
    80221 gtgtttaagg cgattggcga ggcgcaagaa cgcatcattc ttgaaacgtt tatctggttt
    80281 gaggatgacg tcggcaaaca gctgcatgcg gcgctactgg cagcagcgca acgcggggtg
    80341 aaagcggaag tcttgctgga tggctacggt tcgccggatc tcagcgatga gtttgtcaat
    80401 gaactgacgg cagctggcgt ggtatttcgc tactacgatc cccgcccgcg cctttttggt
    80461 atgcgcacca atgtgtttcg ccggatgcat cgcaaaattg tggtgatcga cgcgcttatc
    80521 gcctttattg gcgggctgaa ttactccgcc gagcatatgt ccagctacgg tccagaggct
    80581 aaacaggatt acgcggtgcg ccttgaaggg ccgattgtcg aagatattct gcaatttgaa
    80641 ctggaaaacc tgccaggaca gagcgcggca cgacgctggt ggcgacgtca tcacaaagcg
    80701 gaagagaacc gccagccggg agaagcgcag gtattgctgg tctggcgcga taacgaagaa
    80761 catcgcgatg atattgaacg tcactatctg aaaatgctca ctcaggcgcg gcgagaagtg
    80821 attatcgcca acgcctactt cttccccggc tatcgatttt tacacgcctt gcgtaaagcg
    80881 gcacggcgcg gggtgcggat caaactgatc attcagggcg aaccggatat gccgattgtc
    80941 agagtcggtg cgcgtttgct gtataactat ctggttaaag gcggcgttca ggtttttgag
    81001 taccgccgcc gcccgctcca cggcaaagta gcattgatgg acgatcactg ggcgacagta
    81061 gggtccagta atctcgatcc gctcagtttg tcactgaatc tcgaagcaaa tgtcatcatc
    81121 cacgatcgtc attttaacca gacgctgcgc gataatctga acggcatcat cgccgcagat
    81181 tgtcagcagg tggatgaaac catgctgccc aaacgcacct ggtggaacct gactaaaagc
    81241 gtgctggcgt tccacttttt acgccacttc ccggcgctgg ttggctggct tccggcacac
    81301 acgccacgtc tggcgcaggt tgatcccccc gcacaaccga caatggaaac gcaggatcgg
    81361 gtagaaactg aaaacacggg ggtaaaaccc tgatgagtaa atcacaccca cgctggcgct
    81421 tagcaaagaa actcctcacc tggctgtttt ttatcgcggt gattgtgttg ttggtggtct
    81481 acgccaaaaa agtggactgg gaagaggtct ggaaggtcat ccgcgactac aatcgcgttg
    81541 cgctgcttag tgcggtcggg ctggtggtcg tcagttatct gatttacggt tgctacgacc
    81601 tgctcgcccg tttctactgc ggtcacaaac tggcgaagcg ccaggtgatg ctggtgtcgt
    81661 ttatctgcta cgccttcaac ctgacactca gtacctgggt cggcggcatt ggtatgcgct
    81721 atcgtttgta ctcccgactg gggttaccgg gcagcactat tacgcggatt ttttcgctca
    81781 gtattaccac caactggcta ggctatattt tgctagcggg ggttatcttt accgcaggcg
    81841 tggtggagtt gccggaccac tggtatgtcg atcaaaccac gctgcgcatt ctcggcattg
    81901 gcttactgat gattatcgcg gtttatttgt ggttttgcgc tttcgcgaag caccgccata
    81961 tgaccatcaa aggacaaaaa ctggtgctgc cttcatggaa attcgccctc gcccaaatgc
    82021 tgatttccag tgttaactgg atggtaatgg gggcgattat ctggctgtta cttggtcaaa
    82081 gcgtgaacta tttctttgta ctgggcgtgt tactggttag tagtattgct ggcgtcatcg
    82141 tgcatattcc agcggggatt ggtgtgctgg aagcggtgtt tatcgcgcta ctggctgggg
    82201 agcatacatc caagggcaca attatcgccg ccctactcgc ttaccgtgtg ctgtattact
    82261 ttatcccgct gctgctggcg ctggtttgct atctggtact ggaaagccag gcgaagaagc
    82321 tgcgggcgaa aaatgaagcg gcgatgtgaa gtatagttaa gttctttagt atgtgcattt
    82381 acggctaatg aaaaaaccgc gtatgccttt gccagacaag cgttatagct atagcggcaa
    82441 gaatcccaaa gaagccgata aaatagtaat agagtgttaa tgcacctata aaagcacaac
    82501 gaaccggact ccataattct tcactatggc tttttcctgt caattcaagg agcttatttc
    82561 gtccatgcga gataatgcct gaccataaga caatcattaa gcaacttatt acccaaatgg
    82621 gtcgttcact cattaatgtg gcattcacga tgattaccag ggccaaccct gccaacgtca
    82681 tcataatgat aaaacggtga gaaccaggat caaatttaaa caatagacct gccagcatac
    82741 tgattaaaaa catcgatccc gcagtgctga acacgacgat aatggcagat acaggcgcta
    82801 aactcgcaac gacaatcgcc accaaagaga ttaaaaacag atatattacg cctgcgatgg
    82861 cggcatttat cttgttgata tccttactta agccatacat acaaagtaat aataatccta
    82921 tagcaatata catttgcggt gaatcatatt ttgttgccgt aatttcgaga tacttagcgc
    82981 cccaggccag ccctgcggtt gccaccaaac ccaaagcggt aatgagccat atgccgttta
    83041 atatcctggc ttcgtgctga aaatctaatt tattgctatt ttgcgagaat gattccattc
    83101 tttttgttgt ccttagaaaa aaacattaat attcaccatc aataaattta aaaccacgca
    83161 tacaaaatac ttttgcattt atggatacag aaaacacttc cgctcggcca taaggcatat
    83221 tttatacctg gtacttgtta agtgtcgttt ttagtaagaa aaaaaatccc ggcaccaggc
    83281 cgggatattg atggtgaaaa aagaattaac ggcggttgcc gaagatccgc agcaacatca
    83341 ggaacaggtt gatgaagtcc agatacaagg tcaacgcgcc aagaatggaa tatttgcgca
    83401 ggttcgacgt gtcgcgggta tcaatctgct cacccatatt tttcagtttc tgggtgtcat
    83461 acgccgtcaa tccgacaaag acaatcacgc cgatgtatgt gactgcccac atcaacgctt
    83521 cgcttttcag ccagaagttg accagcgatg ccagcacaat gccgatcaac gccataaaca
    83581 gcatattgcc gaaaccactt agatcgcgct tcgtggtgta accgtacagg ctcattgcgc
    83641 cgaacatccc ggcagtaacg acgaaagtac tggcgataga agcagcggta tagacaatga
    83701 aaatactgga aagcgtcagg ccagtcagcg cggaataaag cataaagagc atcgtcgtta
    83761 cacctgcgct cagcttttga atcatcgctg ataacacaat aaccagagct aattgtgcta
    83821 ttaccagacc aattaaaaag atgcggttgg tgaataatag ctccataacg gccgcggaat
    83881 tagccgcata ccaggcaaca aacgcagtaa gcagcaagcc tactgtcatc cagccataga
    83941 cctgtgccat ataggtttgc aggccagttc gggtttgtac gattgaatca gaacgtggga
    84001 atctgtccat gacgatctcc tgaagatata aggaatatct taaggatact gcaaaatgat
    84061 gaggctgtgc atcgacgcag cgtaaacgca tatactgagc ggtgaaattg ccggacgcag
    84121 cggtgcctta tccggctaac aaaaaactac cagcgttttg ccgcctgctg atcgctctcc
    84181 cgagcttcga cccagcggtc gccttccggc gtggcttcgc gcttccagaa cggtgcgcgg
    84241 gttttgagat aatccataat aaactgcccg gcttcaaacg cactgctgcg atgcgcactg
    84301 gtgacaccga caaaaacgat ttcatcgccc ggccataatt ccccgatgcg gtgaatcacc
    84361 gtgacgcgcc ccagcggcca gcggttacgc gcttcatcga caatttctgc cagtgctttt
    84421 tcagtcatcc ccggatagtg ttcgagggtt aatgctttga cgctgtcgcc aaggttatgg
    84481 ttgcgcacct taccggtaaa ggtgactacc gcaccgtctt catcacgctc cgccagccac
    84541 ggatactctt ctcctacgct gaacggctgc gggccgataa caattttggt ttctgccatc
    84601 ttaacctccg gttaccggcg ggaagaaagc cacttcgtcg ccgtcagtca gcggatggtc
    84661 aaaactcacc agcgtctggt tgacagcagc cagcaatttg ccatcttcca gcgccagcgc
    84721 ccagcgatcg ctctgcgcag ccagatgttg gcgtaacgct tcaacggttg ggaaatccgc
    84781 agctacttcg gttgcatctg ttcccaccaa ctcgcgcacc tgggcgaaaa aaagaacttt
    84841 aatcatccgc ttccacctta aagtcacctg atttgccgcc gctctttgcc agcaaacgta
    84901 ccggaccaat caccatatct ttttgcaccg ctttgcacat gtcataaatg gtcagcgccg
    84961 ccacggaggc cgcggttaat gcttccattt cgacaccggt tttcccggtc aggcggcata
    85021 aggtttctat acgtacccga ttgtgctccg gctcagcctg taaattgact tcaactttgc
    85081 tgagcatcag cgggtgacac agcgggatca gatcccaggt gcgttttgcc gcctgaatac
    85141 cggcaatacg cgcagtggca aatacgtcgc ctttgtggtg gcgaccatca ataatcatcg
    85201 ccagcgtctc gctgcgcatg gtgacaaagg cttcggcgcg cgcttcacgc acggtttccg
    85261 ctttggcgga gacatccacc atgtgcgctt cgccagcggc gttgatatgg gtcagttgcg
    85321 acatacttat ttcttcaaat gtggatggaa attacacgga cgcgtacggg catccagctg
    85381 cggcgcaatg atattttccc atgcggtacg gcacgctttg gtcgaacccg gcatggcgaa
    85441 aatcagcgtt ttgttagcga cgcccgctac cgcacgagat tgcaacgtgg aagtgccaat
    85501 ctcttcgaac gacaacatcc ggaacacttc accaaaacct tcaacttcac ggtcgaacaa
    85561 cggcagcagc gcttcgggag cctgatctcc ttccgtcagg ccagtaccac ccgtaatcaa
    85621 caccacttgt acatcgtcgc tggcgatcca cgcagatacc tgagcgcgaa tagcgtagcg
    85681 gttttctttc acaatggctt tatcgacaac gtgatggccc gcttcttgcg ccgagtcgcg
    85741 cagatagtga ccggaggtat cgtcttcttc accgcgacga ttagaaaccg taagaatagc
    85801 aatacgggtc gggataaatt cagtgcttac ctgactcatc tgatctctcc ttttgacgtt
    85861 ttagccacca atgtacgata agttttgcgt aataccggtg ttgttttgat gcaggaaatg
    85921 ggtctgtttt ttctcccgca gcgccgctga aatacgcgct tccagcgcct gttgctgggt
    85981 atcgtcttcc agcagatcgc gcaggttaac gccgccttca ccaaacaggc agagatggag
    86041 tttaccaatg gaggaaacgc gcaggcggtt gcaagtggcg cagaagtctt tttcatacgg
    86101 catgataagg ccaatctctc cggcgtaatc cggatgacaa aagacttgcg cgggaccgtc
    86161 gctgcgttga cgtaattggt ggatccagcc gcgacgcagt agctcgtccc gcagaacctg
    86221 accagagatg tgatgcttac ggaagagctc gctgccctcg cccgtttcca tcaattcgat
    86281 gaaacgcagc tggatagggc gatgctggat ccagttcaga aaggtgtcga gctgatgatg
    86341 attaacatca cgcatcagca cggtattgac tttgaccttc tcaaaaccgg cctcaaatgc
    86401 agcatcgatc cctgccatga cctggttgaa tttatcctgc ccggtaatgg catgaaactg
    86461 gcgagcgtca aggctatcaa cgctgacgtt gatgccagta agtccagcat cgcgccagtt
    86521 cgccacatcg cgttccagac ggtaaccatt ggtggtgacc gcaatctggc ggatagcgtc
    86581 gttttctcgc acagcggcga tgatatcggt aaagtcgcgg cgtaaagatg gctcaccgcc
    86641 cgtcagacgg actttttcgg tgccaagact ggcgaaggcg cgcgtaaccc ggcgaatttc
    86701 atcgacggta agaaagcctt tattggtgac gccgctcggt ttgtagccat ccggcaggca
    86761 gtaggtgcaa cgaaagttac acacatcggt aatcgacagg cgcaagtagt aaaacttacg
    86821 cgcaaatgca tcagtcagtt gtgaagccat gtacaccttt ccagatacgg gaggcgaagt
    86881 catttcttcc ttcgccctgg tggcaatctt tacgagcatt gtcacggcca aagcaccgta
    86941 tcagttgacc caggtgcaga ggctagagtg tttagtggtt aagccgatac tagcgtgtaa
    87001 atgagatttt taccatccac actttcgcta tgtaatcatg tatatagcgt catgatcgtg
    87061 ctatttcgct acagaataag ggaaaatggc ggttttactt tgatatacat catcaggaag
    87121 gcatagcgta catcgtcctt tagaggtaga agaaaatagt ttgtatcctc aatattggca
    87181 ggttaattgc tgtttccccg caatttgcgc tactgtagcg cggataatct gactccagga
    87241 aactatatgc gcaatcgtac gctggctgac cttgatcgtg tcgttgctct cggcggaggg
    87301 catggactgg gacgcgttct ctcatcactt tcgtctttgg gttctcgttt aacgggtatc
    87361 gtcaccacca cggataatgg tggctcgacg gggcgtattc gccgctcaga aggcggtatt
    87421 gcctggggcg atatgcgtaa ctgcctcaac cagctgataa ctgaacccag cgtcgcttcc
    87481 gcaatgtttg aatatcgttt cggcggtaat ggcgaacttt ccggacacaa ccttggaaac
    87541 ctgatgctga aggcactgga tcaccttagc gtgcgacctc ttgaagcgat caatctgatt
    87601 cgcaatctgc tgaaagtgga cgcacatttg attccgatgt cggagcatcc tgttgatctg
    87661 atggcgattg acgatcaggg gcatgaagtt tacggcgagg tcaatatcga ccagttaact
    87721 gcgccgattc aagagttatt gttaacgccg aatgtacccg caacgcgtga ggcggttcac
    87781 gctatcagtg aagcggatct catcattatt gggcctggca gtttttacac cagcctgatg
    87841 ccaattctgc tgctgaagga aatcgcacag gcattacgcc gcacgccagc gccgatggtc
    87901 tatatcggca atctggggcg tgagttgagt ttacctgcgg ctaatttgaa gctggaaagc
    87961 aagctggcaa ttatggagca gtatgtcggt aaaaaagtga ttgatgcggt agttgttggg
    88021 ccgaaagctg atgtatccgc agttaacaac agaattgtga ttcaggaagt actggaggcc
    88081 agcgatatcc cctatcgtca tgaccgccag ttgttacata acgcgctgga aaaggcatta
    88141 caggctttag gttaacacga agccggaaga atattccggc ttcgtcatct tgtcacgacg
    88201 cggcaataaa cagctcacgc agctgatgca actggtcacg aatttgcgcc gcttcttcga
    88261 actccagatt ctgcgcgtgt tgcatcatca acccttccag ttcatggatc ttctgctgca
    88321 acgctttagg cgacatatcc atcggcacat tatctggctc aacaatcggg cgcgattttc
    88381 ctctgccctt cgctttggtt ttggcaatgt tctgccccag cgccaggata tcgaccactt
    88441 tcttgttcaa gccttgcggc gtaatgccgt gttcctcgtt gtacttctgc tgtttctcgc
    88501 ggcgacgttc ggtttcgcca atcgctttcg ccattgatgg ggtgatctta tcgccgtaga
    88561 gaatcgcttt accgttaacg ttacgtgccg cacgaccaat ggtctggatc aacgaacgtt
    88621 cggaacgcag gaagccttct ttgtcagcgt cgaggatcgc caccagcgac acttccggca
    88681 tatccagacc ttcgcgcagt aagttgatcc ctaccaatac gtcgaactca cccagacgca
    88741 agtcgcggat aatctccata cgttcgacgg tgtcgatatc tgagtgaaga taacgcacgc
    88801 gctcaccgtg ttcttcgaga tattcagtga gatcttccgc catccgcttg gtcagagttg
    88861 taaccagtac gcgttcgtta attgccgctc gctgacgaat ctccgataga agatcatcga
    88921 cctgtgtcgc taccggacgc acttcaataa tcgggtcaag taagcctgtt ggacgcacca
    88981 cctgatccac cacatcgccg ccggattttt ccagctcgta attacccggc gtcgccgaaa
    89041 catagatggt ttgcggcgct aatgcttcga actcttcaaa tttcagcgga cggttatcca
    89101 gcgctgatgg caggcggaag ccgtactcca ccagcgtctc tttacgcgcc cggtcaccgc
    89161 gatacatgcc gccaatttgc ggaatggtaa cgtgagattc atcgaccacc agcagcccat
    89221 cggcaggcag gtaatcaaac agcgtcggcg gtggctcacc cggtccacga ccggagagga
    89281 agcgcgagta gttttcaatc cccgaacagt agcccagctc gttcatcatc tccagatcaa
    89341 actgggtacg ctgggtcagc cgctgctctt ccagcagttt gttgttttcc aacagcacat
    89401 tgcgtctggc agccagttct tctttaattt cttccatcgc ctgcacaatg cgctcgcgcg
    89461 gtgtgacgta gtgcgttttc gggtagatgg taaaacgtgg aatagtggaa acaatctgcc
    89521 cggtgagcgg atcaaataac gacaatcgtt ccacttcctc gtcaaacagt tccacgcgaa
    89581 gtgcaatgtc atccgattct gccgggaaga tgtcaatcac ctccccacga acgcggaaag
    89641 taccgcgctg gaaggcttga tcattacgag cgtattgcag ctccgccagt cgacgcagga
    89701 tcgcgcgctg atcgataatc ataccgaccg taagatggag catcatcttg agatataaat
    89761 caggatcgcc cagaccataa atcgcggaaa ccgatgccac cacaaccaca tcacgccgct
    89821 ccagcatcgc tttggtggcg gacaaacgca tctgctcgat atgttcgttt accgaggcat
    89881 ctttctcaat gaaggtgtcg gaactcggta cataggcttc cggctgataa tagtcgtagt
    89941 aggagacgaa atactccacc gcgttttccg ggaagaactc tttcatttcg ccatacagct
    90001 gggccgccag cgttttgttg ggcgcaagta ccatggtagg gcgctgaagg tcagcaatga
    90061 cattggcaat ggtgaaggtt ttcccggagc cagtcacgcc aagtaacgtc tggtgcgcca
    90121 ggccatcttc cagcccctct tcgagacgtc gaatcgcctc tggctgatcg ccagaaggtt
    90181 taaaagcgga attcagtttg aacggtttac tcatgagtcg ctacctgaag gagttgggcg
    90241 ggcaggtatg taattttact cgtcgtactt aattatgcca acaaattata ctggataaaa
    90301 aaacagtttc tcaccataat atttctgtta cagcgtaaac tcagctgtca atcatgagca
    90361 aaatttactc tgtggcgaga taaaactccg gccttaccgg gttatcccca aagcaacggc
    90421 ttttttaaca tttgtcaaga tgagtgatga cagttttatg gcaagagatg cctcttcagt
    90481 gactgccatt gcaattatct aaccagttaa aaaataaaag atatttcttt gagccgtctt
    90541 taacgccaat tcgcgtgcaa gccgcgtatt ctctcgcttg cctcgtgttt tctaactcta
    90601 atacacatgg ttatccacag gaatagtgga taactgtctg cagcccctat cccccgccgc
    90661 ctgggcaatt cccacattca ccgcatgatg cggaggtaaa atttttttcg tgattttttt
    90721 agaatttaat tggttaaatt gcagtcaatc gaagacgcga tctcgctcgc aatttaacca
    90781 agtacaggat gactacatta aggcaagatt gatgtacttt ccggttgccg cattttctgg
    90841 attttctgca agccagggaa tttcgcccag cagcggagcg ggaatcatgc gggtgagcgt
    90901 ggtcatatat tcagcgtgac gttttcccgg aggcgtgaca tcgttcgcca cccaacccgc
    90961 cagagtcagt ccggcgtgta gtattgcctg tgccgtcaac atcgcgtgat taatacagcc
    91021 gagtttcaca ccaactacca gtatcaccgg cagttgttcc tgtgttaccc aatccgcaaa
    91081 agtgaaagtg tcagaaagcg gcgtaaacca gccgccagcg ccttccacta acacccagtc
    91141 agcctgttgt tcaagcgcgc gtaatccggc gctcattacc aatgcttcta tcggcctgcc
    91201 ctcttgcgcg ctgatgatgt gcggcgaggt gggttctgcg aaggtgtaag gatttaccgt
    91261 tgcgtaatcc agctgcaggc tactgttgcg ctgtaacgcc agcgcgtcac tattacgtaa
    91321 gcctttcggg gtcttttcgc tgccagaggc caccggtttg taacctgccg tccggtagcc
    91381 tgctgccttt gcggcttgta aaagtgcaca actggcgacg gttttcccca cttcggtatc
    91441 cgttccggtg acaaaataac gtttactcac gagcaatcac tcccaaaaaa agatgatacg
    91501 tcagaggata tcgcccctgt ttttgtggcc aggccagttg caatcgctgc aactgcgaac
    91561 gcgttaatat ccgcgggtcg cgcccttcat gaagatgcgt ggcaccgatg cctttcagcg
    91621 aacgcatggc actgagcgca tcatcaaacc acagcgtgat gggctgaata tgatgttgat
    91681 aatgcaggcc gttcagcgac tgttcgattt catctggcgg taaagagcga ttagcatgcg
    91741 ggcgctcgtc caccgcctgc cacgcctgat gtaattcagg gagcgatccc tgcaccagcg
    91801 tggtaaacgc gaccacgcct ccggggcgca ccacgcgata cagctcgcga agtgccgtgg
    91861 ataaattacc gcaccactgc accgcgagat tgctccatgc aagatcgaag gttgcagtcg
    91921 ctaacggcag ggattcgata tctcccgcca gataatggtc tgcggcatcc ttctggcgtg
    91981 cctgaacaag cattggcggc gagagatcta acgccgtcac ctgcgcgtga cgttcacgcc
    92041 agtggcggct catccagcca ggtccacaac ccgcatccag tacgtgggtg tatttacgct
    92101 gtgggagcat tgccagtaag acgtcagcac tctggcgctg tagatccgca tgttgctcat
    92161 agtgcgcggc tgcccgacca aatgccgctg caatggcttg tttattaacc gttgccatgc
    92221 agcacctcca gcagacggtc gatatcctgc atttcatgcg cggcagttag tgttaagcgc
    92281 agtcgcgcag taccagcagg tacggttggc gggcgaatcg ccgtgaccca gcagccttgc
    92341 tggcgcagtt tttctgccag ttgtaacgca cggctgttat caccgacgat caatggctgg
    92401 atggcgctcc atgaatcagc aagcgtaaac ggcaaatcct gcactccggc acgaaaacgc
    92461 gcaatgagtg acaccagttt ttcgcgccgt gcatcaccct catcactgcg aatgaccgcc
    92521 agcgacgcac gtaatgcctg cgcctgagcg ggcggcatac tggtgctgta gataagatgg
    92581 cgggcgaatt gcagcagata atccgccacc gtactggagc aaagcaccgc tgccccactg
    92641 acgccaaatc ctttgccaaa agtcaccacc agcaattctg gttttacctt ttgcagccag
    92701 cagctgccac gcccctgctc cccgataacg cccgtgccgt gggcatcatc gaccatcaac
    92761 cagccattgt gctgttgcgt tacttgctgg atttccgcca gtggcgcact atcgccgtcc
    92821 atgctgaaca cgccttctgt caccaccagt tgctgccccg gacaggggga agcaagcagt
    92881 cgcgccagat gagtgacatc gttatgagca aaacggcgaa gctgcgacgg gcttaaactg
    92941 gcagcttcca gcaatgaggc atggctaagc cggtcagcaa caatgcggtc ctcttttgcc
    93001 atcatcgcgg caatgaccgc ctgattagcg gcaaaaccag agataaacag cagtgcccgc
    93061 gaatagccca gccactcggc cagttcttct tccagcgcct gatgcgccac gctataaccg
    93121 ctgacgtgac cggagccgcc gctaccgacg ccaaattgct ccgcactctg cttccaggca
    93181 cggataattt gcggatgatg gcttaaacct aaataatcgt tactggaaaa gttcagatac
    93241 tggcgatcgt ccgccaccag ccagcgtccg gctccttgcg ccactggata acggcgacgc
    93301 agggcatcgg cagcacgccg cgcatcgagc gccgcgttga ttttctcctg ccagctcata
    93361 gtgctgccgc gttgtaatat tcgtcagtgt ccggggtcat cagcgcctgc tccagacgct
    93421 gctgttgttc gttatcgccc gccagcacgg cagtttgctg cggatttagc cccagtttgc
    93481 ggaacagttg caggtcttta tcttcttccg gattcggcgt ggtcagcagt ttgcaaccgt
    93541 agaaaatcga gtttgcgcca gccataaagc acatcgcctg agtctgttcg ttcatctgct
    93601 cgcgtccggc agaaaggcgt acgtaagagg tcggcatcat gatccgcgca actgcaatgg
    93661 tgcgaataaa atcaaaggca tcgacatcat cgttatcagc aagcggcgtg cctttcacct
    93721 tcaccagcat gttgattggt acgctttccg gcggcgttgg caggtttgcc agttgcagca
    93781 ataatccggc gcgatctttt actgtttcgc ctaagcccac aatgccgccc gagcagactt
    93841 tgatcccggc gtcgcgcact ttttccagcg tatcgaggcg ttcctgatag gtacgcgtgg
    93901 tgatgatatt gccgtaaaac tccggcgagg tgtcgaggtt gtggttgtag taatccagcc
    93961 cggcattcgc caggcgctgc gcctgagatt cactcaacgt gcccagcgtc atacacgcct
    94021 ccagccccat cgcttttacc ccctgcacca tttgttccag gtacggcata tcgcgttcgt
    94081 ggggattctt ccacgccgcg cccatgcaga agcgcgtcga tcctgccgct ttcgctttgc
    94141 gcgccgactc cagcacctgt tcaacttcca tcaaccgctc ggcttccagc ccggttttgt
    94201 agcgcgagct ttgcgggcag tatttgcaat cttccggaca agctccggtc ttaattgaca
    94261 gcaaagtgct gacctgcacc tgacgaggat cgaaatgctg acgatgcacc tgctgcgctt
    94321 caaacagcag atccagcaac ggtttttcaa ataattctgt gacttgcgac aatgtccagc
    94381 gtgggcggtg agccatgggg cttctccaaa acgtgttttt tgttgttaat tcggtgtaga
    94441 ctcgtaaacc taaatctttt caatttggtt tacaagtcga ttatgacaac ggacgatctt
    94501 gcctttgacc aacgccatat ctggcaccca tacacatcca tgacctcccc gctaccggtt
    94561 tatccggtgg cgagcgccga aggttgcgag ctaattttgt ctgacggcag acgccttgtt
    94621 gacggtatgt cgtcctggtg ggcggcgatc cacggttaca atcacccgca gcttaatgcg
    94681 gcgatgaaat cgcaaattga tgctatgtcg catgtgatgt ttggcggtat cacccatgcg
    94741 cccgccattg agctgtgccg caaattggtg gcaatgacgc cgcaaccgct ggagtgcgtt
    94801 tttctcgcgg actccggctc cgtagcggta gaagtggcga tgaaaatggc gttgcagtac
    94861 tggcaggcca aaggcgaagc gcgccagcgt tttctgacct tccgcaatgg ttatcatggc
    94921 gatacctttg gcgcgatgtc ggtgtgcgat ccggacaact caatgcacag cctgtggaaa
    94981 ggctatctgc cagaaaactt gtttgctccc gctccacaaa gccgcatgga tggcgaatgg
    95041 gatgagcgcg atatggtggg ctttgcccgc ctgatggcgg cgcatcgtca tgaaatcgcg
    95101 gcggtgatca ttgaaccgat tgtccagggc gcaggcggga tgcgcatgta ccatccggaa
    95161 tggttaaaac gaatccgcaa aatgtgcgat cgcgaaggta tcttgctgat tgccgacgag
    95221 atcgccaccg gatttggtcg taccggcaaa ctgtttgcct gtgaacatgc agaaatcgcg
    95281 ccggatattt tgtgtctcgg taaagcctta accggcggca caatgaccct ttccgccacg
    95341 ctcaccacgc gcgaggttgc ggaaaccatc agtaacggcg aagccggctg ctttatgcat
    95401 gggccaactt ttatgggcaa tccgctggcc tgcgcagcag caaacgccag cctggcgatt
    95461 atcgaatctg gcgactggca gcatcaggtg gcggctattg aagcgcagtt acgcgagcaa
    95521 cttgcccccg cctgtgacgc cgaaatggtt gccgatgtgc gcgtactggg ggcaatcggc
    95581 gtggtcgaaa ccactcgtcc ggtgaatatg gcagcgctgc aaaaattctt tgtcgaacag
    95641 ggtgtctgga tccggccttt tggcaaactg atttacctga tgccgcccta tattattctc
    95701 ccgcaacagt tgcagcgtct gaccgcagcg gttaatcgtg cggtgcagga tgaaacattt
    95761 ttttgccaat aacgggaagt cagcgtgagg gtttctggct acactttctg caaacaagaa
    95821 aggagggctc atgaaactca tcagtaatga tttacgcgat ggcgataagt tgccacatcg
    95881 tcatgtcttt aacggcatgg gttacgatgg cgataatatt tcaccgcatc tggcgtggga
    95941 tgatgttcct gtgggaacga aaagttttgt tgtcacctgc tacgacccgg atgcgccaac
    96001 tggctccggc tggtggcact gggtagttgt taatttaccc gcggataccc gcgtattacc
    96061 gcaagggttt ggctctggtc tggtagcaat gccagacggc gttttgcaga cgcgtaccga
    96121 ctttggtaaa accggatacg atggcgcagc gccgccgaaa ggcgaaaccc atcgctacat
    96181 ttttaccgtt cacgcgctgg atgtagaacg tattgatgtc gatgaaggtg ccagcggcgc
    96241 gatggtcggg tttaacgttc attttcactc tctggcgagt gcctcgatta ctgcgatgtt
    96301 tagttaatca ctctgccaga tggcgcaatg ccatctggta tcacttaaag gtattaaaaa
    96361 caactttttg tctttttacc ttcccgtttc gctaaagtta gtataaaaaa gcaggcttca
    96421 acggattcat ttttctattt catagcccgg agcaacctgt gaacacattt tcagtttccc
    96481 gtctggcgct ggcattggct tttggcgtga cgctgaccgc ctgtagctca acaccgcccg
    96541 atcaacgtcc ttctgatcaa accgcgcctg gtacctcttc tcgcccgatt ctgtcggcaa
    96601 aagaagcgca gaatttcgat gctcaacact attttgcatc cctgacacca ggtgcggcag
    96661 cgtggaatcc ttccccgatt accctgcctg cgcaacctga ctttgttgtc ggcccggcgg
    96721 gtactcaagg tgtaacgcat accacgattc aggcggcggt agatgcggca attatcaagc
    96781 gtaccaacaa gcgccagtat attgccgtga tgcctggtga gtatcaggga acggtgtatg
    96841 tccctgccgc tccgggtgga attactctgt acggtacagg tgaaaaaccg attgatgtga
    96901 agattgggct ttcccttgat ggtggcatga gccctgccga ctggcgtcac gacgtcaacc
    96961 cgcgcggcaa atatatgcca ggtaaaccgg cgtggtatat gtacgatagc tgccagagta
    97021 aacgcagcga cagtatcggt gttctctgct ctgcggtctt ctggtcacaa aacaatggcc
    97081 tgcaactgca aaacctgacc atcgaaaaca cgctgggcga tagcgtagat gcgggtaacc
    97141 atccggcggt ggcactgcgt actgatggcg acaaagtgca gatcaataac gtcaacattc
    97201 tcggtcgtca gaacaccttc tttgtcacca acagcggtgt gcagaaccgt ctggaaacca
    97261 accgtcagcc gcgtacgctg gtgaccaaca gctatattga aggggatgtg gatatcgttt
    97321 ctggtcgcgg cgcagtggtg ttcgataaca ccgaattccg cgtggtgaac tcccgtaccc
    97381 agcaagaagc gtatgtgttt gcaccggcta cgctgtccaa catttactac ggtttcctcg
    97441 ccgtaaacag ccgtttcaat gcttccggtg atggcgtggc acaactgggc cgctcgctgg
    97501 atgttgatgc caataccaac ggtcaggtag tgatccgtga tagcgccatc aacgaaggtt
    97561 ttaacacggc gaaaccgtgg gccgatgcgg tgatttccaa tcgtccgttt gcgggtaata
    97621 ctggcaacgt tgatgataac gacgaagtac agcgcaatct gaatgacact aactacaacc
    97681 gcatgtggga atacaataac cgcggcgtgg gtagcaaagt ggttgcagag gcgaagaagt
    97741 aaaaaaagaa aacccgatag tctgaaccat cgggttaatg aaactgggcg ctatatttca
    97801 tagcgccttt ttttacatct gacggttttt attgaagtta atcaaactac ccgccttgat
    97861 aatctcgcgc tcttcagcag tcagactttc catatagagc gtaatctctg ttaccggcgc
    97921 atcttcatgg atcacataac ctttaaacgt cgtacccgga ttatccagcg ctgctttaat
    97981 gccagggatg taaatgtaat cacctacgtc aaagttcggt gcttccgcca tctgcagcgg
    98041 taacatcccc cagttgatga cgttagaacg gtagcgttta gtcgcgtact cctcggcaat
    98101 attcgccaga ccgccaatca cacgctgaca gctcgccgcc tgctcacgcg cagaaccatc
    98161 gcctggtttc accgcataga ccatgctgcc aatttcagtt tgcagcggat caatatgctc
    98221 ctgaccagca atctgcttaa tgcgcgcaaa cacctctgtc agctcgctga catttcccgc
    98281 cagacgctga ttttccagct cagcagtcgc tttacttcta ccaacataac ctggatcgcg
    98341 gcgtgacagg gtaaactccg ccagaccaat cggatttgaa cgataagaag aggtttcacc
    98401 ggaaggaatc agttcgtcgg tggtggtcac ttcgtcgagg atcttcgagc acactttgag
    98461 gacgatattg tcagtcagcg cacccaattc cggccagtct ttaatgttcg gtccgtaaat
    98521 cagcggttgc tgggtcgccc ctttcacaaa gccctgataa acacggtttt tatacggcgt
    98581 tacatcgaag gcgtactccg gcacgttgtc ccagcaatcg agttcgctgg cagaggttaa
    98641 atagccaccg tttgccgcag tcgcagcgat agaacgagcg tccatcaacg ccaccgctga
    98701 catctgacca ttagctggct tagagccttc gcggttcggg aagttacgcg tggtgtggcg
    98761 aatactcaaa ccgttattga ttggtgtatc gcccgcgcca aagcatgggc cgcagaacgc
    98821 ggttctgatg attgcgcctg cgccaatcaa atctgctacc acaccttttt tggcgagatc
    98881 cataaacacg ggctgtgatg acgggtaaac cgctaacgag aaggtgtcat tgccacagga
    98941 ttgaccgcgc agcgcattcg ccgccgcgat gacgttttca tagttaccgc cagaacagcc
    99001 cgcgataatc ccctgctgca ctttcaggcg accattttcc actttatcca gcagcgagag
    99061 tctggcttta ccgtgcgcca cacgttcgga ctcaatttca atctcacgca gaatgtcggt
    99121 caggttctgg ttcagcgtgt cgatttcata cacgttgctc gggtggaatg gcagcgcaat
    99181 cattggtttg atggcgctta aatcaacgct gatgcagcca tcgtagtacg ccattggttg
    99241 agggttaagt tggcagtaat cctggccgcg accgtgcagc gccagccagt tatggacttc
    99301 ttcatcggtt tgccagacag aacttaaaca ggtcgtttca gtggtcatca cgtcaacgct
    99361 gttacggaaa tcggtagaga gcgctgcaac accgggacct acgaactcca tcactttgtt
    99421 tttgacgtaa ccgtttttga acacggcacc gatgatagcc agcgccacat cctgtggccc
    99481 cacatacagc gctggttttc cggtcagatg caccgcaacc acgcccggat agtcgatatc
    99541 ccaggtgtca ttaagcagtt gttttaccag ctcgccgccg ccctcgccaa ccgccattgt
    99601 ccctaacgca ccgtaacggg tatggctgtc tgacccgagg atcattttgc cgccgcctgc
    99661 catcatttca cgcatatatt gatggatgac cgcaatatgc ggtggcacaa aaataccgcc
    99721 ataacgctgg gccgccgata aaccaaaaac atggtcatca ccgttaatgg tgccgccgac
    99781 ggcgcagagt gagttatggc agttggtcag cacatacggc agcgggaaac gttccatacc
    99841 ggacgcttta gcggtctgta caataccaac aaaggtaata tcgtgagagg ctaatgaatc
    99901 aaacttaatt ttaagtttat ccatatttcc ggacgtatta tgagaagaga gaatagacca
    99961 ggcaatagtg ccttttttgg cttcttcttt tttaatttcg ccggtgaaat attcttcggc
   100021 aattatttcg ttattactgg cgagaaacac gcctttttca gataacttga tcatcaaatg
   100081 ctccagatat ctgcgcaccg tgaagtgcgc agaaagataa taaatggata tactctaaat
   100141 aattcgagtt gcaggaaggc gacaagcgag tgaatcccca ggagcttaca taagtaagtg
   100201 actggggtga gcgaacgcag acgcagcaca tgcaacttga agtatgacga gtatatttac
   100261 agcatgttcc agccgatcag catattccac caccacacgc cgagggtgat atgcaccagg
   100321 aaggttaata tcgtcagtac cgcaccgacc aaccaccagg atttaatatc gttgtaaccc
   100381 acgccaaaga tgaccggacc tgccgcgccg ccatagtgag taaccatgcc gccataggag
   100441 ttagagaaca acagtgccag cgcggttaac attaacggcg cgccggagac gttcgccagc
   100501 atggcaaata ccggtaacat ggcaacgata taggcactac cggaagcgaa gaaataacgc
   100561 acgatgatgc tgaggaaaat aataacgaag aaagcaacgt taccgtgacc atcaaatgcc
   100621 aggttatttt taaagacttc agctaaccat tcgaagaatt taactttcga taataaggag
   100681 cttaagccga taataccgcc gtaccagatt aaggtattcc agccgccttt atttttaacc
   100741 acgtcttccc aggtaacgat acccagcagc agcatagtcg ccataacaac gattgccacg
   100801 gtggattcat caacccccag tgacttactg aaaatccagc ccagcagcgc cagcacgaag
   100861 acaccgagca gcattttttc gcggattttc atcggtccca gttcggcaag gcccgctttg
   100921 gcgatggttt tgttatccac cttcttaatt tctggcggat acatggtgta aatcaccagc
   100981 ggggtgacca gcagcataat gatgccaggc aatccggcgg ctagcgccca tccaccccag
   101041 ctaatttgca ggtgcagaat gtcgttgatc attttcagcg ccagaatgtt ccccgccatt
   101101 gcggtaaaga acatatagct ggtggttttg gtgaccatgt aaatggacat catcaggtaa
   101161 tgtccaacac gacgcggact tttttccggt tctgatccca aagccactgc cacgctgttg
   101221 atgatcggta acacgatgcc gcccgcacgc gcggtgttag acggtgttgc cggagccagt
   101281 accagatcga gaaataccgt aacgtaaccc agacccaggg tagtgctacc aattttacca
   101341 atcagcagat aggcaatacg tttacctaag cctgtggtta caaacgcggc gcttaaagta
   101401 aacgcagaaa acaccagcca ggtggtaccg gaagagtaac cgcttaatac agcggtggtt
   101461 ttaaattccc cacctgataa gttacccacc actaccatcg atgcggcgac ggcaattaac
   101521 agtacgacag gttccgggaa aggcttgata accagcccca caatggccgc caggtaaata
   101581 ccaaaaagca cccacgccag ttcgcttaat cctgctggag ctggcataaa gccaataata
   101641 catgggattg ctaatatcag aattagcttc cataacgatt tcttattcat ttaatatcct
   101701 gttctttctg tatgactcat acagaattcc tttattgatt gtcattatca cgacaacaaa
   101761 atttttcagg gaagataaac ttcaccggaa aatatttttc tggtcgtccg aataacagat
   101821 gcgcgtaacg tcgtggcatc ctgaccttca ttacttaaat gaacgtcgag cgcaccactg
   101881 gggtgttcaa tattgatatt gccgtatcct acagaaggga cgatttgtcg ggtgacggtg
   101941 ccttccaatg cacaactact ggaaatagca atagcaccgg ttatcgccaa agcgcgatgg
   102001 caagaatgcg gcataaaata acgcacatta attgccccgc ctttctgcgc tggagaaata
   102061 agtacaggtt tagggataac catattactg acatcgccta agcccattgc tttacccgct
   102121 tgtagacgga tagattcaat gcgggctaat aatgctttgt cggcatccag ctctgccggt
   102181 aattcatagc ctgtttttcc cagatattca gcaggaataa tgacaactgg catcgccata
   102241 tcgatacagg tcaccggcac atcgtcaaaa taatcaatct gattatccgt cgggaagact
   102301 tttccggttt tggttccggc ggcattcagg aaagtgagcg caaccggtgc ggcagtaccc
   102361 ggtacgccgt caattctggc gctaccctcg tactcgacaa caccatttgg cgtttgcaca
   102421 tcagcttcga tgaacgtacc cgtattgacg ttgcggatac gtacgcgggt aactggcgaa
   102481 gtcgctgcaa tcaaaccatt ttcaatggcg aatgccccaa cgccagacag catattgccg
   102541 cagttaggcg tggtatcgac acgttgctca tggacgataa cttgagcaaa cagataatcg
   102601 acatctgcac gcggatcgct ggagcggcta ataatggcga ctttactggt cagcggatta
   102661 ccgccgccaa taccgtcaat ttccagatcg ttaccggaac ccataattgc catcaatatt
   102721 ttatcgcgct gcgtttgatc ttcgggtaga tgttccgcta acaggaacgc gcccctcgag
   102781 gttccacctc gcatcatcac gcagggtatt tttttcataa taatgccctc aatttaaaaa
   102841 cataacttat tgcgatatgg ttacattaag ggcaaagcat ctctaatgac tttagctcaa
   102901 cgattaataa ctttttttca ttaatttaag ttggctaaat gcagttaaaa tttttaacgg
   102961 ccagccaccc aaaatcgacg cttccatttt ccggagtaat aatgaagcat gaattatcaa
   103021 gtatgaaggc atttgtcata ctggcagagt ccagttcatt taacaatgcc gctaaattac
   103081 tcaatattac gcaacctgca ttaacgcgaa gaataaaaaa gatggaggaa gatttacata
   103141 tccaactatt tgagcgtaca actcgcaagg ttacgttaac aaaagcagga aaaagattgc
   103201 tcccggaggc gcgggaatta ataaagaaat tcgatgaaac gctttttaat attcgtgata
   103261 tgaatgctta tcatcgtggt atggtgacat tagcgtgtat tccgaccgca gtattttatt
   103321 ttttaccgct ggcaatcggt aaatttaatg agctgtatcc caatattaaa gtgcggattc
   103381 tggaacaagg cacgaataat tgcatggaat cggtgctgtg taacgaatca gactttggca
   103441 taaacatgaa caacgtcaca aattcatcca tcgattttac cccactggtc aacgagccgt
   103501 tcgtgctggc ctgtcggcgt gaccatccat tggccaaaaa gcagcttgta gaatggcagg
   103561 agttagtggg ttacaaaatg attggcgtac gctcctccag cggcaaccga ctgttgatag
   103621 aacaacagct agccgacaag ccctggaagc tggactggtt ttacgaagtg cgtcatcttt
   103681 cgacgtcatt aggactggtg gaggcaggac tggggatttc ggcgcttcct ggtctggcaa
   103741 tgccccatgc gccctattct tcgattattg gtatcccact ggtggaaccc gttatacgtc
   103801 ggacattggg gattattcgc cgcaaagatg ccgtgctttc tccggcagct gaacgctttt
   103861 ttgccttgct gattaatttg tggactgacg ataaagacaa tttgtggacc aatatcgtcg
   103921 aacgccagag acatgcgtta caggagatag gttaatacac cggcgcagga gagactgcgc
   103981 cgggtaaatc agcggttagt gtgcgttaac caccacccac attggtccct gcccgaccgc
   104041 atagcggcct ttttcatgca gtagcccctg ctcgccaaca atttcgtata ccgagatgtg
   104101 gtgagatttt tgcccggcgg caatcagata cttgccgctg tgatcaacat tgaagccgcg
   104161 cggctgggtt tccgttggct ggaagccttc tttactcaac acgctgccat cttccgaaac
   104221 gctgaaaacg gtaatcaggc tggcggtacg gtcgcaggcg tataaatgac gaccatccgg
   104281 ggtgatatga atatcagccg cccaacgggt gtcggagaag ttttccggca tcatatccag
   104341 cgtctggaca cattcgatat tgccgtgcgg atctttcagt tcccagacat ccactgagct
   104401 gtttaactca ttgacgcaat acgcatattg ttcgtttgga tggaatacca tatgacgcgg
   104461 gccggcccct tcaacggtag tcacttccgc agggtcctgc gccaccagat gaccatcctc
   104521 gctgacagta aacaggcaaa tgcgatcctg ctttaatgcc ggaacccaca gcgtacggtt
   104581 gtccggtgag atattggcgg aatggcaacc gtccagcccc tcgaccacat cgacgacgcc
   104641 cactggcagg ccatcttcca gacgcgttac gctcacgtta cccgcattgt aagaaccgac
   104701 aaagacaaac tgcccctggt gatcggtgga aatatgcgtc ggactacccg gcagcgcaga
   104761 ctctgcggca aaggtcagcg cgccatcgtc cggggcgata cgatacgcca ggacgcgaaa
   104821 ctcagggcga acaccaacat agagataacg tttgtccggg ctgaccacca tcggctgcac
   104881 ctgccccggc acatcgacaa cctgtgtcag cgtcagtgcg ccttcatgat tcagattcca
   104941 gacgtgaatt tgctggctct cagggctggc gatataaact gtttgcttca tgaatgctcc
   105001 tttgcattta gcaactgact gtaacagcta aaattagtcg cttttggcgg tgaatgctga
   105061 attaaaacgc agaattttgt ccgatagtgg tatcggtgta ccattcgcgc agacgaaaat
   105121 tcttaacctt aatctggaat acgccatgac cacacgcgtg attgctctcg acttagacgg
   105181 caccttattg accccgaaaa agaccctgct tccatcatcg atagaagccc tggcccgtgc
   105241 tcgcgaagca ggctatcgat taatcatcgt cacaggtcgc catcacgtcg ctattcatcc
   105301 tttttatcag gcgctggcgc tggatacacc tgctatttgc tgtaatggca cctatttgta
   105361 tgattatcat gcaaaaacag tgctggaagc ggacccaatg cccgttaata aagccctgca
   105421 actcattgag atgctgaatg aacaccacat tcacggtctg atgtatgtcg atgatgcaat
   105481 ggtctatgag cacccgaccg ggcatgtcat tcgcacgtct aactgggcgc aaaccctgcc
   105541 gccggaacag cgtccgactt tcacacaagt cgcttctctg gctgaaacgg cgcaacaagt
   105601 taacgccgta tggaagttcg ccctgacgca cgatgacctg ccgcaattgc agcattttgg
   105661 taagcatgtc gaacatgaac tgggactgga gtgtgaatgg tcctggcacg atcaggttga
   105721 tattgcacgc ggcggcaaca gcaaaggtaa acgtttgacg aaatgggttg aggcacaagg
   105781 ttggtcgatg gaaaacgtcg tggcattcgg cgataacttt aatgatatca gtatgctgga
   105841 agccgctggt acaggcgtgg cgatgggcaa cgccgatgac gcggtaaaag cgcgcgccaa
   105901 cattgtgatt ggtgataaca ccaccgacag cattgcccag ttcatttata gccacctgat
   105961 ttaatcaggc ggttatcgac acacttttaa tttgcgcgta cagccacagg cctggtttga
   106021 tcgccagttc atccctggcc cacgggctga tacgcgccca cagcgtttta ccgccgactt
   106081 ccagctccac ttccacctgg ccgttgtcgt cataactatt aacaactttt gcccgcaata
   106141 cgttacgaat gctggtttgc tgcggcggtt gtaaaaccag agaaacatcg gaagcctgaa
   106201 tgcggatacg tagcgcagct tgcagcggtt cgtccagctt attgacccac aaatgctgat
   106261 cgcccagcgc cagcgcggtc atcgcgtaat gcggatgatg ctcaagcacc gtcactttca
   106321 gaatgctact ttgttgctct ttcggcagcc acggattcat cacgctactg ccccacactt
   106381 cttccagcgc gccaaaggct ttcacctgac cgttttccag taccatcact ctgtctgcca
   106441 gatggaggat ctcatccagc gaatggctga catacaacat cggaatgttg atttcccgcg
   106501 tcagacgttg cagataaggc aacagttcgc gtttacgcgg aatatccagt gacgccagcg
   106561 gttcatccag caacagcaat tccggtgctg tcagcaaagc ccgaccaatc gccacgcgct
   106621 gtttttcgcc tccggacagg ccgcctggta aacgatcaag caacggttca atgcctaaaa
   106681 gcgccaccag cttatcgaac tgattgacca tgctttttgc catgccgtag cgcaaattgc
   106741 cacgcacttt ataatgcgga aacagccgtg catcctgaaa cacatagcca acgcgacgct
   106801 tttctggcgt caggcagata cctttttcgg catcatttag tacccgacca ttgaggacaa
   106861 tccgcccttt ttgcgggcgc gtcagcccac tgatggcgtt aatcagcgag gtttttccag
   106921 caccagagac accaaaaata gcggtgatgc cattggcggg cagcgtttca ttaatggtca
   106981 ggcaatggtt gcccaacgtc tgggaaaaat tcagttccag catgattagc gccccgcccg
   107041 ttcacggctg attctggcca gccattctga aatcaacagg gagatcatcg ccagcgcaat
   107101 agaaataata cacagtctcg ccgcgccact ttccccgcct ggggtctgga tcagggtata
   107161 catagcagaa ggaatggttc gcgtttcacc aggaatgttc gacacaaagg tgatggttgc
   107221 gccaaattca ccgagcgaac gagcgaatgc cagtaccgta ccaacaataa ttcccggcaa
   107281 cgtcagcggt aaggtaatag tgaagaagac acgccagcgc ccggcaccca acgttcttgc
   107341 ggcctgctcc agtttgatat caacaccttc cagcgccaga cgaatcgccc gcaccatcag
   107401 cggaaaagac atgacagcgg cagcgagaac cgcaccacgc cagctaaacg cgaaagaaag
   107461 accaaaccag tcatacagac gttcaccgat aaatccgcgc cgtcccatcg aaactaataa
   107521 taagtaaccg acgaccacgg gcggtaacac cagcggtaga tgcagtacgc tgtcgagcag
   107581 agctttgccc ggaaacgtgc aacgtaccag taaccaggca aaaaagatcc caaacggcag
   107641 gctaaacagc acagccaggg aagaaacttt caggcttaat aaaactgcct gccattctgg
   107701 atcggtcagt atcattactt ggttgtaaat ccgtaacgtt taaagatttc cgcagcctgc
   107761 ggccccttca gataatcata aaatgctttc actgtcgcat tattatgccc ttccacaaca
   107821 gcaaccggat attccacttt tttatgtgaa tcttccggga aggtggcaac cacttttacc
   107881 cctttgctgg caactgcgtc agaaccgtaa acaataccca gcggcgcttc attgcgttcg
   107941 accaacgcca gcgcgccacg aacatcttcc gccggagcca gtttcgggga gagcgtatcc
   108001 catgcgccca gtttttgcag tgcttctttt gcataaatgc cagcagggac atgttccgga
   108061 tcgccaaccg cgaggcgacc gccattcagc agcgaagtcc agttagtttt gctgtcgatg
   108121 gtgaaatctt tctgctcgct ggctttcggt gctacaacga ccaggctatt gccgagcagt
   108181 gtctggcgcg aagccgtatc gatcgctttt ttatcaaccg cataatccat ccatttctga
   108241 tcggcagaaa taaacagatc cgcaggcgca cccgcttcaa tctgacgggc caaagtagat
   108301 gacgaagcga aagaagaaac cacatccacg cctttctctt ttttatactg cgtagcaatg
   108361 tcctgcattg cgttagtcag tgatgcggcg gcgaacaccg tgattttccc ttcatctgcc
   108421 agtgcattgc cagcaacagc gaaagagagt gccgccccgg taaacaagtt caaccattta
   108481 cgagccattg gtaacccctt aatgtaacgt tatgtaggcg tcaatataac ggcaagttcg
   108541 gaattttccc agcagttatt gctaaccttt gtgaggtaga tgagaaaaaa tatcggcagg
   108601 aaaagcagga agttgagaaa aagaaaatgc ccgactaagc gggcattcag ggaatcaatg
   108661 attttgtccg ggctggtctt ttttaccaac accagaaaag atgttgaata cttcaccaag
   108721 accgtaaatc agacccagga tgatggccat cacgacaggt accatgatta cggcgaatac
   108781 cagacttttt aataactcta acatggtcaa ctccagatat agtcatgaga ctattctaac
   108841 cgctaagcac agaaaagcac tccccttttg tgcggtcagc tttgcgtggc gttcgttttc
   108901 cgtcacaata agacttttgc caggacattg ttatgcaggc cgaaatcctt ctcaccctta
   108961 agctccaaca aaaattattc gccgacccgc gccgcatttc gctactaaaa cacattgcgc
   109021 tttccggttc cattagccag ggagcgaaag atgccggtat cagctataaa agcgcctggg
   109081 atgccattaa cgagatgaat cagttaagtg agcatattct ggttgagcgc gcaacaggcg
   109141 gtaaaggtgg cggcggcgca gtactgaccc gctatggtca gcgactgatt cagctctatg
   109201 acttactggc gcaaatccag caaaaagcct ttgatgtgtt aagtgacgat gacgccctgc
   109261 cgctgaacag cctgctggcc gcgatctcac gtttttcact gcaaaccagc gcccgtaacc
   109321 agtggttcgg taccatcacc gcccgcgatc atgatgacgt tcaacagcat gttgatgtct
   109381 tactggctga tggaaaaaca cgcctgaaag tcgcaattac cgcacaaagc ggcgcacgtc
   109441 tggggctgga tgaaggcaaa gaagtgttga tattgctaaa agcgccgtgg gtaggcatta
   109501 ctcaggacga ggcggtcgcg caaaacgctg acaaccaatt accgggtatt attagtcata
   109561 ttgagcgcgg cgcagagcag tgcgaagtat taatggcgct acccgacggg caaacactgt
   109621 gcgccacagt gccggtaaat gaagcgactt ctcttcagca aggacagaat gtcacggcct
   109681 actttaatgc cgacagcgtg attatcgcca cgctgtgcta agcgtgttga caatttgtta
   109741 tgaaacacgt atccctgtca gtaatcgctg cacaaaatgg gatataaaat gtcatcgttg
   109801 caaattttgc aaggcacgtt tcgtcttggc gacacaaaaa cgctgcaatt gcctcggcta
   109861 acgttaaacg cgggtgatag ttgggcgttt gtcggttcga atggaagcgg gaaatcggcg
   109921 ctggcccgcg cgctgtcggg ggaacttccg cttttgaaag gtgaacggca aagccagttt
   109981 tcccacatca ctcgtctctc cttcgagcaa ttgcaaaagc tcgtcagcga cgaatggcag
   110041 cggaataaca ccgatatgct tagtcctggc gaagatgaca ccgggcgtac cacggctgag
   110101 atcattcagg atgaagtaaa ggatactccg cgttgcatgc aactggcgca gcagttcggt
   110161 attaccgccc tcctcgaccg acgctttaaa tacctttcca ctggcgagac gcgaaaaacc
   110221 ctgctgtgtc aggcgctgat gtcggagcct gacttgttga ttcttgatga gccgttcgat
   110281 ggcctggatg ttgcctcacg tcagcagctg gctgagctac tcgcctcgtt acatcagtcc
   110341 ggtattactc tggtactggt gctcaatcgc ttcgatgaga tcccagaatt tgtccagttt
   110401 gctggcgtgc tggcggattg cacgttagcg gaaactggcg ctaaagaaga actgctccaa
   110461 caagcactcg tcgcgcaact ggcacatagc gaacagcttg aaggtgtgca actgccggag
   110521 ccggatgaac cttcagcacg tcacgcctta cccgccaacg aaccgcgcat tgtgctgaac
   110581 aacggcgtgg tttcttataa cgatcgcccc attcttaata accttagctg gcaggtgaat
   110641 ccaggcgaac actggcaaat tgtcgggcca aatggcgcgg gaaaatcgac gttattaagc
   110701 ctgattactg gcgatcatcc gcaaggttac agcaacgatt tgacgctttt cggacgacgt
   110761 cgcggcagcg gcgaaaccat ctgggatatc aaaaagcata tcggttacgt cagcagtagt
   110821 ttgcatctgg attaccgggt cagcactacc gtgcgtaatg tgattctttc tggctatttt
   110881 gattcgattg gcatttatca ggccgtttcg gatcgccagc aaaaactggt gcagcagtgg
   110941 ctggatattc tcggtattga taaacgcacg gctgacgctc cgttccatag tctttcctgg
   111001 ggacagcagc gtctggcgct gatcgtccgc gcactggtga aacatccgac gttgcttatt
   111061 ctcgatgaac cactacaggg gctggacccg ctcaatcgcc agcttatccg ccgttttgtt
   111121 gatgtgctga ttagcgaagg tgaaacgcaa ttgttgtttg tttcgcacca cgctgaagat
   111181 gcgcctgcct gtattaccca tcgtctggag ttcgtgccgg acggtgactt ttatcgctat
   111241 gcgctgacaa aaataaactg agtcggtaat gctgactgta ccggaggcgg cctaagcgcc
   111301 ctctccggcc tacagttaga cgcatccagg cataaaaccg agactttttt cagataaaaa
   111361 gcgcaatcat tcataaaccc tctgttttat aatcacttaa tcgcacataa aaaacggcta
   111421 aattcttgtg taaacgattc cactaattta ttccatgtca cacttttcgc atctttgtta
   111481 tgctatggtt atttcatacc ataagcctaa tggagcgaat tatgagagtt ctggttaccg
   111541 gtggtagcgg ttacattgga agtcatacct gtgtgcaatt actgcaaaac ggtcatgatg
   111601 tcatcattct tgataacctc tgtaacagta agcgcagcgt actgcctgtt atcgagcgtt
   111661 taggcggcaa acatccaacg tttgttgaag gcgatatccg taacgaagcg ttgatgaccg
   111721 agatcctgca cgatcacgct atcgacaccg tgatccactt cgccgggctg aaagccgttg
   111781 gcgaatcggt acaaaaaccg cttgaatatt acgacaacaa tgtcaacggt actctgcgcc
   111841 tgattagcgc catgcgcgcc gctaacgtca aaaactttat ctttagctcc tccgccaccg
   111901 tttatggcga tcagcccaaa attccatatg ttgaaagctt cccgaccggc acaccgcaaa
   111961 gcccttacgg caaaagcaag ctgatggtgg aacagatcct caccgatctg caaaaagccc
   112021 agccggactg gagcattgcc ctgctgcgct acttcaaccc ggttggcgca catccgtcgg
   112081 gcgatatggg cgaagatccg caaggcattc caaataacct gatgccatac atcgcccagg
   112141 ttgctgtagg ccgtcgcgac tcgctggcga tttttggtaa cgattatccg accgaagacg
   112201 gtactggcgt gcgcgattac atccacgtaa tggatctggc ggacggtcac gtcgtggcga
   112261 tggagaaact ggcgaacaag ccaggcgtac acatctacaa cctcggcgct ggcgtaggca
   112321 gcagcgtgct ggacgtggtt aatgccttca gcaaagcctg cggcaaaccg gttaattatc
   112381 attttgcacc gcgtcgcgag ggcgaccttc cggcctactg ggcggacgcc agcaaagccg
   112441 accgtgaact gaactggcgc gtaacgcgca cactcgatga aatggcgcag gacacctggc
   112501 actggcagtc acgccatcca cagggatatc ccgattaagg aacgaccatg acgcaattta
   112561 accccgttga tcatccacat cgccgctaca acccgctcac cgggcaatgg attctggttt
   112621 caccgcaccg cgctaagcgc ccctggcagg gggcgcagga aacgccagcc aaacaggtgt
   112681 tacctgcgca cgatccaaat tgcttcctct gcgcaggtaa tgtacgggtg acaggcgata
   112741 aaaaccccga ttacaccggg acttacgttt tcactaatga ctttgcggcc ttgatgtctg
   112801 acacgccaga tgcgccagaa agcaacgatc cgctaatggg ttgccagagc gcgcgcggta
   112861 ccagccgggt gatctgcttt tcaccggatc acagtaaaac gttgccagaa ctgagcgttg
   112921 cggcattgac ggaaatcgtc aaaacctggc aggagcaaac cgcagagctg ggaaaaacgt
   112981 acccgtgggt acaggtcttt gaaaacaaag gcgcggcgat gggctgctct aacccgcatc
   113041 cgcacggaca gatttgggca aatagcttcc tgcctaacga agctgagcgc gaagaccgcc
   113101 tgcaaaaaga atatttcgcc gggcagaaat caccaatgct ggtggattat gttcagcgcg
   113161 agctggcaga cggtagccgt accgttgtcg aaaccgaaca ctggttagcc gttgtacctt
   113221 actgggctgc ctggccgttc gaaacgctac tgctgcccaa agcccacgtt ttgcggatca
   113281 ccgatttgac cgacgcccag cgcagcgatt tggcactggc gttgaaaaag ctgaccagtc
   113341 gttatgacaa cctcttccag tgctccttcc cctactctat gggctggcac ggcgcgccat
   113401 ttaatggcga agagaatcaa cactggcagc tgcacgcgca cttttatccg cctctgttgc
   113461 gctccgccac cgtacgtaaa tttatggttg gttatgaaat gctggcagaa acccagcgag
   113521 acctgaccgc agaacaggca gcagagcgtt tgcgcgcagt cagcgatatc cattttcgcg
   113581 aatccggagt gtaagaaatg agtctgaaag aaaaaacaca atctctgttt gccaacgcat
   113641 ttggctaccc tgccactcac accattcagg cgcctggccg cgtgaatttg attggtgaac
   113701 acaccgacta caacgacggt ttcgttctgc cctgcgcgat tgattatcaa accgtgatca
   113761 gttgtgcacc acgcgatgac cgtaaagttc gcgtgatggc agccgattat gaaaatcagc
   113821 tcgacgagtt ttccctcgat gcgcccattg tcgcgcatga aagctatcaa tgggctaact
   113881 acgttcgtgg cgtggtgaaa catctgcaac tgcgtaacaa cagcttcggc ggcgtggaca
   113941 tggtgatcag cggcaatgtg ccgcagggtg ccgggttaag ttcttccgct tcactggaag
   114001 tcgcggtcgg aaccgtattg cagcagcttt atcatttgcc gctggacggc gcacaaatcg
   114061 cgcttaacgg tcaggaagca gaaaaccagt ttgttggctg taactgcggg atcatggatc
   114121 agctaatttc cgcactcggc aagaaagatc atgccttgct gattgactgc cgctcactgg
   114181 ggactaaagc agtttccatg ccgaaaggtg tggctgtcgt catcattaac agtaacttca
   114241 aacgtaccct ggttggcagc gaatacaaca cccgtcgtga acagtgcgaa accggtgcgc
   114301 gtttcttcca gcagccagct ctgcgcgatg tcaccattga agagttcaac gctgttgcgc
   114361 atgaactgga cccaatcgtg gcgaaacgcg tgcgtcatat cctgactgaa aacgcccgca
   114421 ccgttgaagc tgccagcgcg ctggagcaag gcgacctgaa acgtatgggc gagttgatgg
   114481 cggagtctca tgcctctatg cgcgatgatt tcgaaatcac cgtgccgcaa attgacactc
   114541 tggtagaaat cgtcaaagct gtgattggcg acaaaggtgg cgtacgcatg accggcggcg
   114601 gatttggcgg ctgcatcgtc gcgctgatcc cggaagagct ggtgcctgca gtacagcaag
   114661 ctgtcgctga acaatatgaa gcaaaaacag gtattaaaga gactttttac gtttgtaaac
   114721 catcacaagg agcaggacag tgctgaacga aactcccgca ctggcacccg atggtcagcc
   114781 gtaccgactg ttaactttgc gtaacaacgc agggatggta gtcacgctga tggactgggg
   114841 tgcgacttta ctttccgccc gtattccgct ttccgatggc agcgtccgcg aggcgctgct
   114901 tggctgcgcc agcccggaat gctatcagga tcaggccgca tttctggggg cctctattgg
   114961 tcgttatgcc aaccgcatcg ccaatagccg ttataccttt gacggtgaaa ccgtgacgct
   115021 ttcgccaagt cagggcgtta accagctgca cggcggcccg gaagggttcg acaaacgtcg
   115081 ctggcagatt gtgaaccaga atgatcgtca ggtgctattt gccctgagtt cagatgatgg
   115141 cgatcagggc ttcccgggta atctcggcgc gacggtgcaa tatcgtctga ccgacgataa
   115201 ccgtatctcc attacttatc gcgccacagt tgataaacct tgcccggtga atatgactaa
   115261 tcacgtctat ttcaatcttg acggcgagca gtctgacgcg cgcaatcata agttgcagat
   115321 tctggcggac gaatatctgc cggttgatga aggcggcatt ccgcacgacg gtctgaaatc
   115381 tgtcgccgga acctcttttg atttccgcag cgccaaaatc atcgccagtg agtttcttgc
   115441 cgacgacgat cagcgcaaag tgaaaggtta cgatcacgcg ttcttgttac aggccaaagg
   115501 cgatggcaag aaagtggcgg cgcatgtctg gtcagcagat gaaaaattgc agctgaaggt
   115561 ctacaccacc gctccggctc tgcaattcta ctccggcaac ttcctcggcg gcacaccgtc
   115621 gcggggaacc gaaccttacg ccgactggca agggctggct ctggaaagcg aatttctgcc
   115681 ggacagcccg aaccaccctg aatggccgca accggactgc ttcctgcgtc ctggcgaaga
   115741 gtattccagc ctgacggaat atcagtttat tgctcagtaa tgttaagccc tcgtcatgag
   115801 ggctttatcc tcatattgtt caaatcacca gcaaacaccg acatatttgc aactcaatat
   115861 tcacaacaac cttacactgc gacactattt tcgctatggt tatgcgtaag cattgctgtt
   115921 gcttcgtcac ggcaatataa tgagaattat tatcattaaa agatgatttg aggagtaagt
   115981 atatggctgt aactaagctg gttctggttc gtcatggcga aagtcagtgg aacaaagaaa
   116041 accgtttcac cggttggtac gacgtggatc tgtctgagaa aggcgtaagc gaagcaaaag
   116101 cagcaggtaa gctgctgaaa gaggaaggtt acagctttga ctttgcttac acctctgtgc
   116161 tgaaacgcgc tattcatacc ctatggaatg tgctggacga actggatcag gcatggctgc
   116221 ccgttgagaa atcctggaaa ctgaacgaac gtcactacgg tgcattgcag ggtctgaaca
   116281 aagcggaaac cgctgaaaag tatggcgacg agcaggtgaa acagtggcgt cgtggttttg
   116341 cggtgactcc gccggaactg actaaagatg atgagcgtta tccgggtcac gatccgcgtt
   116401 acgcgaaact gagcgagaaa gagctgccac tgacggaaag cctggcgctg accattgacc
   116461 gcgtgatccc ttactggaat gaaaccattc tgccgcgtat gaagagcggt gagcgcgtca
   116521 tcatcgctgc acacggtaac tcgttacgtg cgctggtgaa atatctcgat aacatgagcg
   116581 aagaagagat tcttgagctg aatatcccga ccggcgtgcc gctggtttat gagtttgacg
   116641 agaacttcaa accgctgaaa cgctattatc tgggtaatgc tgatgagatc gcggcgaaag
   116701 cagcagccgt tgcgaaccag ggtaaagcga agtaaacgtc attcgtttaa aaatgagaaa
   116761 gccgactgca agtgagtcgg cttttttgtt tgtcgttgct aacaatggag cacattgcct
   116821 gatgcgacgc tgcgcgtctt atcaggcctc cggtgattaa tcggatacgc cactctgacg
   116881 gcgcatccga caattaaact ttacccgcga cgcgctttta ctgcattcgc cagttgacgt
   116941 aacagagcat cggtatcatc ccagccaatg caggcatcgg tgatgctctt gccataggcc
   117001 agcggttccc cactctcgag gctctgattg ccttccacca gatggctttc caccatcacg
   117061 ccaataatag ccttttcgcc accggcaatc tgctggcaaa cgtcagcaca aacatccatc
   117121 tgctttttga attgtttgga cgagttggcg tggctgaaat cgatcatcac ctgcgctggc
   117181 agacctgctt tgttcagccc gtctttcact tcagcaacgt gcttcgcgct gtagttaggc
   117241 tctttaccgc cgcgcagaat gatatggcaa tcgccgttac cgctggtatt cacaatcgcc
   117301 gaatgccccc atttcgttac ggacaggaag cagtgcggcg caccggcggc attaatagca
   117361 tcgatagcca ctttaatcgt accatcagtg ccatttttga agcctaccgg gcaagaaaga
   117421 ccagacgcca gttcgcggtg cacctgcgat tccgtagtac gtgcgccaat tgcgccccag
   117481 ctcatcaggt cagcgagata ttgtggggtg atcatatcca ggaattcacc cgccgctggc
   117541 agaccgctgt cgttaatatc gagcagcaat ttgcgggcaa tacgcagacc gtcgttgatc
   117601 tggaagctgt tatccatatg cggatcgtta atcagccctt tccagcccac cgttgtacgc
   117661 ggcttttcaa aatagacgcg cattacgatt tccagctcat ctttcagctc ttcacgcagc
   117721 gccagcaagc gagtggcata ctcttttgct gcgacaggat catgaattga gcatgggcca
   117781 atcaccacca acaggcgatc atcattacct ttcaggatct tatggatcgc ttttcgggca
   117841 tgggcgaccg tattcgcggc attttcagta gcggggaatt tttccagcaa tgcgacagga
   117901 ggaagtaact ctttgatttc tttgatgcgt aaatcgtcgt tctgataatt catgtctgtt
   117961 ccagtgttgc catacttatc ttagtgaatg caatacttcc aatctatatc ttccgtcaga
   118021 atgtgtaaac ggggttttac actatgaacg gattaatcct ggaattagca agaaaaacgc
   118081 cagattgtcg cgaaaaacga gatctctcct acaatttcta actgtaactc ctttgtttgt
   118141 taattatttc aagattctct gctgggtatc tttgcctggc tgaaatctta aaccattgcc
   118201 ttatattcac ctgcaaatgc actgttggaa gaggttatcc gacataacga ccataacagg
   118261 agcatcctat gaaaatgaca aaactggcca cactattttt gactgccact ctaagccttg
   118321 ccagcggtgc cgcactggct gccgatagcg gagcacaaac taataacggc caggcaaacg
   118381 ccgcagctga tgcgggccag gtagcccctg acgcccgtga aaatgtcgcg ccaaataacg
   118441 tcgacaataa cggggtaaat accggttctg gtggcacaat gctgcattcg gatggttctt
   118501 caatgaacaa tgacggaatg accaaagatg aagagcacaa gaacaccatg tgcaaagatg
   118561 gccgctgtcc tgatatcaat aaaaaagtcc aaaccggtga tggcatcaac aatgatgtcg
   118621 ataccaaaac cgacggtacc acgcagtaac cctgcgaaat agccaataat gggagagcgg
   118681 agtctctccc ttttaatttt tcccttctaa aagcagtatg atgtcataaa gttaagtgag
   118741 aataattaag ggatgactcg tcatggcgca ctcacactca cacacttcct cacacctgcc
   118801 agaagataat aatgctcgtc gcttgttgta tgctttcggc gtgactgccg ggtttatgct
   118861 cgtagaagtc attggtggtt ttctttccgg ttctctggca ttgctggccg atgcgggtca
   118921 tatgttgacc gatactgccg ccctgctttt cgccctactc gcagtgcaat tttcccgtcg
   118981 tcctcccacc attcgccaca ctttcggttg gctaagattg accacgctcg cggcgtttgt
   119041 gaatgccatc gccctggtgg tgattactat tttgattgtc tgggaggcga tagaacgctt
   119101 ccgcactccg cgtccggtcg agggcggcat gatgatggca attgccgtgg ctgggctgct
   119161 ggcaaatata ctttctttct ggttacttca tcacggcagc gaagagaaaa acctcaacgt
   119221 gcgagcagcg gcactgcatg tgctcgggga cctgctgggt tcggttgggg ctattattgc
   119281 cgcgttgatt attatctgga ccggctggac acctgctgac cccattctct caatactggt
   119341 gtcgcttctg gttctgcgta gcgcgtggcg actgttgaaa gatagcgtga atgaattact
   119401 tgaaggtgca ccggtatcgc tggatatcgc cgaactgaag cgtcgtatgt gccgggaaat
   119461 cccggaagtc cgcaatgtgc accatgtaca tgtatggatg gtaggcgaga agccggtgat
   119521 gacgctgcat gtgcaggtga tcccgccaca cgatcacgat gccttgttag atcagatcca
   119581 acactacctg atggatcact atcagattga gcacgccact attcagatgg aatatcaacc
   119641 ttgtcatggg ccagactgcc acctgaatga aggggtgtct ggccattcac atcatcacca
   119701 ttaatgggac agcgcgcgtg agcctctttc gcgtgcgctg ttgatccaca tccggctgcc
   119761 gttgagcgca ataaaggtca ggatgatgta ctccagagac atggcgtaaa cgccctgaag
   119821 tgcaaaaata acgacgctaa tcacgttaat aatcacccac aacagccagt tttccacata
   119881 tttacgcgtc atcagaatca ttgccacgat agataacacc atcatgcagg aatcccagaa
   119941 cgggaaagcg tccggttgca gttcaggcat cgcaacctgt aatcctaatg cttgcatgat
   120001 gatgactgcc acgcgggtca aaaatgcaaa caccggattg ataaataccg tcatcagacc
   120061 aatcgaaaca acgcaaaccg ccaaccagca tagcgccttc ggcaatggca accagcgaat
   120121 tttcaactcc gcctcgttct gactggtttg tcgcgaccac gcataccagc cgtaaatatt
   120181 cgcggcaaag aaaaacatct gtaatagcag gctggcatac agctgaatct gaaagaaaat
   120241 aatgccaaac aaggtgacgt tgatcaggcc aaagaagtag ttgctgatct tctccagact
   120301 ggcaaggcca atacacaaca acccggcgat cgtgcctacc gcttcgatcc atgagagatc
   120361 ataaccgcct gctcctattg gtatatgtac caggatattc tgcacactaa aaaaatccat
   120421 ctttccccca aagcgtaacg ttacgcctta ttattcgtta tccacgtagt gtagccgcaa
   120481 aatccagcat acgattgagc ggcaccagcg ccctctctcg cagcctttca tcaacatgaa
   120541 cctcgtgatt gcttccttcc tgttctaatg cctctgcgat ggcctgaagg ccattcatgg
   120601 ccatccacgg acaatgcgcg cagctgcggc aggttgcacc ctcacccgcg gttggtgctt
   120661 ccagtaactc tttatctggc accgcctgct gcattttgta gaaaatgccc cgatcggttg
   120721 ccacgataag tcgctgatgt ggcaatgttt tcgcagcagc gatcagttga ctggtggaac
   120781 cgaccgcatc cgccatatcg acaatagctt gcggtgattc tggatgcacc agtatggcag
   120841 catccgggta ttcttcttgc aagcgggtta acgcctgagt cttaaactca tcatgcacaa
   120901 tgcaggcacc ctgccaacat aaaatgtctg cgcccgtctg tttttgcacg taacgcccca
   120961 gatgtttgtc gggtgcccag atgatttttt cacccaaact atccagatga tcaataagtt
   121021 cgacggcaat gcttgaagtt accacccaat ctgcccgcgc ttttaccgca gcagaagtgt
   121081 tggcgtagac gacgacagta tgatcgggat gggcatcgca aaatgcgtta aattcttcaa
   121141 cagggcagcc gagatccagt gaacattcag cctgaagtgt cggcatcaga attgtttttt
   121201 ccggactgag aattttggcg gtttctccca taaatctcac ccccgcgact aacaacgtag
   121261 aagcgggatg ctttgcaccg aagcgcgcca tttccagaga atcagaaata cagccaccgg
   121321 tttcttctgc cagttgttga atttcgggat cggtgtagta gtgggcaacc atcaccgcat
   121381 tacgttcttt tagcagacgt tttatcttct cacggtaata cgctttttca tcaatactta
   121441 acggcgtcgg cttcgggggg aaaggataaa tcgccgcttc aggatcaaac atcacgctca
   121501 tcttaccatc tcgttttaca ggcttaacgt taaaaccgac atgagcgtaa tattcgctgt
   121561 tatcggtgaa atttgtttta tatgctaaac aagatagtcg aatggtgggg aaaagtcact
   121621 cgaattacgc ctaattccac cgacgtagag ttgcttgcac agtaagctct gaagatgtca
   121681 tcaggttaca cagtgaaatt gaggatgcct gaatagcaaa aaagcgcctt tagggcgctt
   121741 ttttacattg gtgggtcgtg caggattcga acctgcgacc aattgattaa aagtcaactg
   121801 ctctac
//
LOCUS       DADXDL010000002       116167 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.002, whole genome shotgun sequence.
ACCESSION   DADXDL010000002 DADXDL010000000
VERSION     DADXDL010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 116167)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 116167)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..116167
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.002"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            165..280
                     /gene="rrf"
                     /locus_tag="IRB70_000118"
     rRNA            165..280
                     /gene="rrf"
                     /locus_tag="IRB70_000118"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
     gene            605..1903
                     /gene="kgtP"
                     /locus_tag="IRB70_000119"
     CDS             605..1903
                     /gene="kgtP"
                     /locus_tag="IRB70_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoglutarate permease"
                     /protein_id="HBC0630081.1"
                     /translation="MAESTVTADSKLTSSDTRRRIWAIVGASSGNLVEWFDFYVYSFC
                     SLYFAHIFFPSGNTTTQLLQTAGVFAAGFLMRPIGGWLFGRIADKHGRKKSMLLSVCM
                     MCFGSLVIACLPGYETIGTWAPALLLLARLFQGLSVGGEYGTSATYMSEVAVEGRKGF
                     YASFQYVTLIGGQLLALLVVVVLQHTMEDAALREWGWRIPFALGAVLAVVALWLRRQL
                     DETSQQETRALKEAGSLKGLWRNRRAFIMVLGFTAAGSLCFYTFTTYMQKYLVNTAGM
                     HANVASGIMTAALFVFMLIQPLIGALSDKIGRRTSMLCFGSLAAIFTVPILSALQNVS
                     SPYAAFGLVMCALLIVSFYTSISGILKAEMFPAQVRALGVGLSYAVANAIFGGSAEYV
                     ALSLKSIGMETAFFWYVTLMAVVAFLVSLMLHRKGKGMRL"
     gene            complement(1900..2223)
                     /locus_tag="IRB70_000120"
     CDS             complement(1900..2223)
                     /locus_tag="IRB70_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiM family lipoprotein"
                     /protein_id="HBC0630082.1"
                     /translation="MRILFVCSLLLLSGCSHMANDSWSGQDKAQHFIASAMLSAAGNE
                     YSQHQGMSRDRSAMFGLMFSVSLGASKELWDSRPEGSGWSWKDFAWDIAGASTGYTVW
                     QLTRH"
     gene            complement(2269..3624)
                     /gene="pssA"
                     /locus_tag="IRB70_000121"
     CDS             complement(2269..3624)
                     /gene="pssA"
                     /locus_tag="IRB70_000121"
                     /EC_number="2.7.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--serine
                     O-phosphatidyltransferase"
                     /protein_id="HBC0630083.1"
                     /translation="MLSKFKRNKHQQHLAQLPKISQSVDDVDFFYAPADFRETLLEKI
                     ASAKQRICIVALYLEQDDGGKGILNALYEAKRQRPELDVRVLVDWHRAQRGRIGAAAS
                     NTNADWYCRMAQENPGVDVPVYGVPINTREALGVLHFKGFIIDDSVLYSGASLNDVYL
                     HQHDKYRYDRYHLIRNRKMSDIMFEWVTQNIMNGRGVNRLDDVNRPKSPEIKNDIRLF
                     RQELRDAAYHFQGDADNDQLSVTPLVGLGKSSLLNKTIFHLMPCAEQKLTICTPYFNL
                     PAILVRNIIQLLREGKKVEIIVGDKTANDFYIPEDEPFKIIGALPYLYEINLRRFLSR
                     LQYYVNTDQLVVRLWKDDDNTYHLKGMWVDDKWMLVTGNNLNPRAWRLDLENAILIHD
                     PQLELAPQREKELELIREHTTIVKHYRDLQSIADYPVKVRKLIRRLRRIRIDRLISRI
                     L"
     gene            complement(3738..6398)
                     /gene="pat"
                     /locus_tag="IRB70_000122"
     CDS             complement(3738..6398)
                     /gene="pat"
                     /locus_tag="IRB70_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein lysine acetyltransferase"
                     /protein_id="HBC0630084.1"
                     /translation="MSQRGLEALLRPKSIAVIGASMKPNRAGYLMMRNLLAGGFNGPV
                     LPVTPAWKAVLGVLAWPDIASLPFTPDLAVLCTNASRNLALLEELGEKGCKTCIILSA
                     PVSQHEDLRACALRHNMRLLGPNSLGLLAPWQGLNASFSPVPIKRGKLAFISQSAAVS
                     NTILDWAQQREMGFSYFIALGDSLDIDVDELLDYLARDSKTSAILLYLEQLSDARRFV
                     SAARSASRNKPILVIKSGRSPAAQRLLNTTAGMDPAWDAAIQRAGLLRVQDTHELFSA
                     VETLSHMRPLRGDRLMIISNGAAPAALALDALWSRNGKLATLSEETCQKLRDALPGHV
                     AISNPLDLRDDASSEHYVKTLDILLHSEDFDALMVIHSPSAAAPATESAQALIEAVKH
                     HPRSKYVSLLTNWCGEYSSQEARRLFSEAGLPTYRTPEGTITAFMHMVEYRRNQKQLR
                     ETPALPSNLTSNTAEAHLLLQQAIAEGATSLDTHEVQPILQAYGMNTLPTWIANDSTE
                     AVHIAEQIGYPVALKLRSPDIPHKSEVQGVMLYLRTANEVQQAANAIFDRVKMAWPQA
                     RIHGLLVQSMANRAGAQELRVVVEYDPVFGPLIMLGEGGVEWRPEDQAVVALPPLNMN
                     LARYLVIQGIKSKKIRARSALRPLDVAGLSQLLVQVSNLIVDCPEIQRLDIHPLLASG
                     SEFTALDVTLDIAPFEGDNESRLAVRPYPHQLEEWVELKNGERCLFRPILPEDEPQLQ
                     QFISRVTKEDLYYRYFSEINEFTHEDLANMTQIDYDREMAFVAVRRIDQTEEILGVTR
                     AISDPDNIDAEFAVLVRSDLKGLGLGRRLMEKLITYTRDHGLQRLNGITMPNNRGMVA
                     LARKLGFNVDIQLEEGIVGLTLNLAQREES"
     gene            complement(6430..7128)
                     /gene="tapT"
                     /locus_tag="IRB70_000123"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
     CDS             complement(6430..7128)
                     /gene="tapT"
                     /locus_tag="IRB70_000123"
                     /gene_synonym="tuaA"
                     /gene_synonym="yfiP"
                     /EC_number="2.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311476.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-uridine aminocarboxypropyltransferase"
                     /protein_id="HBC0630085.1"
                     /translation="MTENAVLQLRAERIARATRPFLARGNRVRRCQRCLLPEKLCLCS
                     TITPAQAKSRFCLLMFDTEPMKPSNTGRLIADILPDTVAFQWSRTEPSLDLLDLVQNP
                     DYQPMVVFPASYADEQREVIFTPPAGKPPLFIMLDGTWPEARKMFRKSPYLDNLPVIS
                     VDLSRLSAYRLREAQAEGQYCTAEVAIALLDMVGDTGAAAGLGEHFTRFKTRYLAGKT
                     QHLGSITAEQLESV"
     gene            complement(7197..7616)
                     /gene="trxC"
                     /locus_tag="IRB70_000124"
     CDS             complement(7197..7616)
                     /gene="trxC"
                     /locus_tag="IRB70_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxC"
                     /protein_id="HBC0630086.1"
                     /translation="MNTVCTHCQAINRIPDDRIEDAAKCGRCGHDLFDGEVINATGET
                     LDKLLKDDLPVVIDFWAPWCGPCRNFAPIFEDVAQERSGKVRFVKVNTEAERELSSRF
                     GIRSIPTIMIFKNGQVVDMLNGAVPKAPFDSWLNESL"
     gene            7823..8860
                     /locus_tag="IRB70_000125"
     CDS             7823..8860
                     /locus_tag="IRB70_000125"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HBC0630087.1"
                     /translation="MNDEMKGKSGKVKVMYVRSDDDSDKRTHNPRTGKGGGRPGKSRA
                     DGGRRPARDDKQSQPRDRKWEESPWRTVSRAPGDETPEKADHGGISGKSFIDPEVLRR
                     QRAEETRVYGENACQALFQSRPEAIVRAWFIQSVTPRFKEALRWMAANRKAYHVVDEA
                     ELTKASGTEHHGGVCFLIKKRNGTTVQQWVSQAGAQDCVLALENESNPHNLGGMMRSC
                     AHFGVKGVVVQDAALLESGAAIRTAEGGAEHVQPITGDNIVNVLDDFRQAGYTVVTTS
                     SEQGKPLFKTSLPAKMVLVLGQEYEGLPDAARDPNDLRVKIDGTGNVAGLNISVATGV
                     LLGEWWRQNKA"
     gene            complement(8908..9597)
                     /gene="ung"
                     /locus_tag="IRB70_000126"
     CDS             complement(8908..9597)
                     /gene="ung"
                     /locus_tag="IRB70_000126"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBC0630088.1"
                     /translation="MANELTWHDVLAEEKQQPYFLNTLQTVASERQSGVTIYPPQKDV
                     FNAFRFTELGDVKVVILGQDPYHGPGQAHGLAFSVRPGIATPPSLLNMYKELENTIPG
                     FTRPNHGYLESWARQGVLLLNTVLTVRAGQAHSHASLGWETFTDKVISLINQHREGVV
                     FLLWGSHAQKKGAIIDKQRHHVLKAPHPSPLSAHRGFFGCNHFVLANQWLEQRGETPI
                     DWMPVLPAESE"
     gene            9902..10285
                     /gene="grcA"
                     /locus_tag="IRB70_000127"
     CDS             9902..10285
                     /gene="grcA"
                     /locus_tag="IRB70_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007728348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autonomous glycyl radical cofactor GrcA"
                     /protein_id="HBC0630089.1"
                     /translation="MITGIQITKAANDDLLNSFWLLDSEKGEARCIVAKAGFAEDEVV
                     AVSKLGDIEYREVPVEVKPEVRVEGGQHLNVNVLRRETLEDAVKHPEKYPQLTIRVSG
                     YAVRFNSLTPEQQRDVIARTFTESL"
     gene            complement(10340..10927)
                     /gene="eamB"
                     /locus_tag="IRB70_000128"
     CDS             complement(10340..10927)
                     /gene="eamB"
                     /locus_tag="IRB70_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/O-acetylserine transporter"
                     /protein_id="HBC0630090.1"
                     /translation="MTPTLLSAFWTYTLITAMTPGPNNILALSSATTHGFRQSTRVLA
                     GMSLGFLIVMLLCAGISFSLAVIDPAAVHLLSWAGAAYIVWLAWKIATSPTKEDGLQA
                     KPISFWASFALQFVNVKIILYGITALSTFVLPQTQALSWIIGVSVLLAMIGTFGNVCW
                     ALAGHLFQRLFRQYGRQLNIVLALLLVYCAVRIFY"
     gene            11030..11911
                     /locus_tag="IRB70_000129"
     CDS             11030..11911
                     /locus_tag="IRB70_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311470.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0630091.1"
                     /translation="MDLRRFITLKTVVEEGSFLRASQKLCCTQSTVTFHIQQLEQEFS
                     VQLFEKIGRRMCLTREGKKLLPHIYELTRVMDTLREAAKKESDPDGELRVVSGETLLS
                     YRMPQVLQRFRQRAPKVRLSLQSLNCYVIRDALLNDEADVGVFYRVGNDNALNRRELG
                     EQSLVLVASPQIADVDFTEQGRHNACSFIINEPQCVFRQIFESTLRQRRITVENTIEL
                     ISIESIKRCVAANIGVSYLPRFTVANELASGELIELPFGEQSQTITAMCAHHAGKAVS
                     PAMHIFIQCVEECFLPG"
     gene            complement(11944..13278)
                     /gene="srmB"
                     /locus_tag="IRB70_000130"
     CDS             complement(11944..13278)
                     /gene="srmB"
                     /locus_tag="IRB70_000130"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase SrmB"
                     /protein_id="HBC0630092.1"
                     /translation="MTVTTFSELELDESLLEALQDKGFTRPTAIQAAAIPPALDGRDV
                     LGSAPTGTGKTAAYLLPALQHLLDFPRKKSGPPRILILTPTRELAMQVADHARELAKH
                     THLDIATITGGVAYMNHAEVFSENQDIVVATTGRLLQYIKEENFDCRAVETLILDEAD
                     RMLDMGFAQDIEHIAGETRWRKQTLLFSATLEGDAIQDFAERLLEDPVEVSANPSTRE
                     RKKIHQWYYRADDLEHKTALLVHLLKQPEATRSIVFVRKRERVHELANWLREAGINNC
                     YLEGEMVQGKRNEAIKRLTEGRVNVLVATDVAARGIDIPDVSHVFNFDMPRSGDTYLH
                     RIGRTARAGRKGTAISLVEAHDHLLLGKVGRYIEEPIKARVIDELRPKTRAPSEKQTG
                     KPSKKVLAKRAEKKKAKEKEKPRVKKRHRDTKNIGKRRKPSGTGVPPQTTEE"
     gene            13410..14147
                     /gene="trmN"
                     /locus_tag="IRB70_000131"
     CDS             13410..14147
                     /gene="trmN"
                     /locus_tag="IRB70_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417070.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA(1)(Val)
                     (adenine(37)-N(6))-methyltransferase TrmN"
                     /protein_id="HBC0630093.1"
                     /translation="MSQSTSVLRRNGFTFKQFFVAHDRCAMKVGTDGILLGAWAPVAG
                     VKRCLDIGAGSGLLALMLAQRTDDSVMIDAVELESEAAAQAQENINQSPWAERINVHT
                     ADIQQWITQQTVRFDLIISNPPYYQQGVECATPQREQARYTTTLDHPSLLTCAAECIT
                     EEGFFCVVLPEQIGNGFTELALSMGWHLRLRTDVAENEARLPHRVLLAFSPQAGECFS
                     DRLVIRGPDQNYSEAYTALTQAFYLFM"
     gene            complement(14132..15754)
                     /gene="nadB"
                     /locus_tag="IRB70_000132"
     CDS             complement(14132..15754)
                     /gene="nadB"
                     /locus_tag="IRB70_000132"
                     /EC_number="1.4.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-aspartate oxidase"
                     /protein_id="HBC0630094.1"
                     /translation="MNTLPEHSCDVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEG
                     STFYAQGGIAAVFDETDSIDSHVEDTLIAGAGICDRHAVEFVASNARSCVQWLIDQGV
                     LFDTHVQPNGEESYHLTREGGHSHRRILHAADATGREVETTLVGKAQNHPNIRVLERS
                     NAVDLIVSDKIGLPGTRRVVGAWVWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD
                     ISSGDGIAMAWRAGCRVANLEFNQFHPTALYHPQARNFLLTEALRGEGAYLKRPDGTR
                     FMPDFDERGELAPRDIVARAIDHEMKRLGADCMFLDISHKPADFIRQHFPMIYEKLLG
                     LGIDLTKGPVPIVPAAHYTCGGVMVDDHGRTDVEGLYAIGEVSYTGLHGANRMASNSL
                     LECLVYGWSAAEDITRRMPYAHDVSTLPPWDESRVENPDERVVIQHNWHELRLFMWDY
                     VGIVRTTKRLERALRRITMLQQEIDEYYAHFRVSNNLLELRNLVQVAELIVRCAMMRK
                     ESRGLHFTLDYPELLTHSGPSILSPGNHYINR"
     gene            16010..16165
                     /gene="rseD"
                     /locus_tag="IRB70_000133"
     CDS             16010..16165
                     /gene="rseD"
                     /locus_tag="IRB70_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rpoE leader peptide RseD"
                     /protein_id="HBC0630095.1"
                     /translation="MIRLQHDKQKQMRYGTLQKRDTLTLCLLKLQLMEWRFDSAWKFG
                     LGRLYLG"
     gene            16162..16737
                     /gene="rpoE"
                     /locus_tag="IRB70_000134"
     CDS             16162..16737
                     /gene="rpoE"
                     /locus_tag="IRB70_000134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005070454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoE"
                     /protein_id="HBC0630096.1"
                     /translation="MSEQLTDQVLVERVQKGDQKAFNLLVVRYQHKVASLVSRYVPSG
                     DVPDVVQEAFIKAYRALDSFRGDSAFYTWLYRIAVNTAKNYLVAQGRRPPSSDVDAIE
                     AENFESGGALKEISNPENLMLSEELRQIVFRTIESLPEDLRMAITLRELDGLSYEEIA
                     AIMDCPVGTVRSRIFRAREAIDNKVQPLIRR"
     gene            16770..17420
                     /gene="rseA"
                     /locus_tag="IRB70_000135"
     CDS             16770..17420
                     /gene="rseA"
                     /locus_tag="IRB70_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-E factor RseA"
                     /protein_id="HBC0630097.1"
                     /translation="MQKEQLSALMDGETLDSELLNELAHNPEMQKTWESYHLIRDSMR
                     GDTPEVLHFDISSRVMAAIEEEPVRQPATLIPEAQPAPHQWQKMPFWQKVRPWAAQLT
                     QMGVAACVSLAVIVGVQHYNGQSETSQQPETPVFNTLPMMGKASPVSLGVPSEATANN
                     GQQQQVQEQRRRINAMLQDYELQRRLHSEQLQFEQAQTQQAAVQVPGIQTLGTQSQ"
     gene            17420..18376
                     /gene="rseB"
                     /locus_tag="IRB70_000136"
     CDS             17420..18376
                     /gene="rseB"
                     /locus_tag="IRB70_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-E factor regulatory protein RseB"
                     /protein_id="HBC0630098.1"
                     /translation="MKQLWFAMSLVTGSLLFSANASATPASGALLQQMNLASQSLNYE
                     LSFISINKQGVESLRYRHARLDNRPLAQLLQMDGPRREVVQRGNEISYFEPGLEPFTL
                     NGDYIVDSLPSLIYTDFKRLSPYYDFISVGRTRIADRLCEVIRVVARDGTRYSYIVWM
                     DTESKLPMRVDLLDRDGETLEQFRVIAFNVNQDISSSMQTLAKANLPPLLSVPVGEKA
                     KFSWTPTWLPQGFSEVSSSRRPLPTMDNMPIESRLYSDGLFSFSVNVNRATPSSTDQM
                     LRTGRRTVSTSVRDNAEITIVGELPPQTAKRIAENIKFGAAQ"
     gene            18373..18852
                     /gene="rseC"
                     /locus_tag="IRB70_000137"
     CDS             18373..18852
                     /gene="rseC"
                     /locus_tag="IRB70_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SoxR-reducing system protein RseC"
                     /protein_id="HBC0630099.1"
                     /translation="MIKEWATVVSWENGQALVSCDVKASCSSCASRAGCGSRVLNKLG
                     PQTTHTIVVPCEEPLVPGQKVELGIAEGSLLSSALLVYMSPLVGLFLIASLFQLLFAS
                     DIAALCGAILGGVGGFLIARGCSRKFAARSEWQPIILSVALPPGLVRFETSSEDASQ"
     gene            19050..20849
                     /gene="lepA"
                     /locus_tag="IRB70_000138"
     CDS             19050..20849
                     /gene="lepA"
                     /locus_tag="IRB70_000138"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBC0630100.1"
                     /translation="MKNIRNFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSM
                     DLERERGITIKAQSVTLDYKASDGETYQLNFIDTPGHVDFSYEVSRSLAACEGALLVV
                     DAGQGVEAQTLANCYTAMEMDLEVVPVLNKIDLPAADPERVAEEIEDIVGIDATDAVR
                     CSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSWFDNYLGVVSLIRIKNGTLR
                     KGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKCGEVGWLVCAIKDIHGAPVGDTLTL
                     ARNPAEKALPGFKKVKPQVYAGLFPVSSDDYEAFRDALGKLSLNDASLFYEPESSSAL
                     GFGFRCGFLGLLHMEIIQERLEREYDLDLITTAPTVVYEVETTSREVIYVDSPSKLPA
                     VNNIYELREPIAECHMLLPQAYLGNVITLCVEKRGVQTNMVYHGNQVALTYEIPMAEV
                     VLDFFDRLKSTSRGYASLDYNFKRFQASDMVRVDVLINGERVDALALITHRDNSQNRG
                     RELVEKMKDLIPRQQFDIAIQAAIGTHIIARSTVKQLRKNVLAKCYGGDISRKKKLLQ
                     KQKEGKKRMKQIGNVELPQEAFLAILHVGKDNK"
     gene            20865..21839
                     /gene="lepB"
                     /locus_tag="IRB70_000139"
     CDS             20865..21839
                     /gene="lepB"
                     /locus_tag="IRB70_000139"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBC0630101.1"
                     /translation="MANMFALILVIATLVTGILWCVDKFFFAPKRRERQAAAQAAAGD
                     SLDKATLKKVAPKPGWLETGASVFPVLAIVLIVRSFIYEPFQIPSGSMMPTLLIGDFI
                     LVEKFAYGIKDPIYQKTLIETGHPKRGDIVVFKYPEDPKLDYIKRAVGLPGDKVTYDP
                     ISKELTIQPGCSSGQACENALPVTYSNVEPSDFVQTFSRRNGGEATSGFFEVPKNETK
                     ENGIRLSERKETLGDVTHRILTVPIAQDQVGMYYQQPGQQLATWIVPPGQYFMMGDNR
                     DNSADSRYWGFVPEANLVGRATAIWMSFDKQEGEWPTGVRLSRIGGIH"
     gene            22112..22792
                     /gene="rnc"
                     /locus_tag="IRB70_000140"
     CDS             22112..22792
                     /gene="rnc"
                     /locus_tag="IRB70_000140"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004248457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBC0630102.1"
                     /translation="MNPIVINRLQRKLGYTFNHQELLQQALTHRSASSKHNERLEFLG
                     DSILSYVIANALYHRFPRVDEGDMSRMRATLVRGNTLAELAREFELGECLRLGPGELK
                     SGGFRRESILADTVEALIGGVFLDSDIQTVEKLILNWYQTRLDEISPGDKQKDPKTRL
                     QEYLQGRHLPLPTYLVVQVRGEAHDQEFTIHCQVSGLSEPVVGTGSSRRKAEQAAAEQ
                     ALKKLELE"
     gene            22789..23694
                     /gene="era"
                     /locus_tag="IRB70_000141"
     CDS             22789..23694
                     /gene="era"
                     /locus_tag="IRB70_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBC0630103.1"
                     /translation="MSIDKSYCGFIAIVGRPNVGKSTLLNKLLGQKISITSRKAQTTR
                     HRIVGIHTEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWT
                     PDDEMVLNKLRDGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNFLDIVPISAETGL
                     NVDTIAAIVRKYLPEATHHFPEDYITDRSQRFMASEIIREKLMRFLGAELPYSVTVEI
                     ERFVSNERGGYDINGLILVEREGQKKMVIGNKGAKIKTIGIEARKDMQEMFEAPVHLE
                     LWVKVKSGWADDERALRSLGYVDDL"
     gene            23706..24434
                     /gene="recO"
                     /locus_tag="IRB70_000142"
     CDS             23706..24434
                     /gene="recO"
                     /locus_tag="IRB70_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBC0630104.1"
                     /translation="MEGWQRAFVLHSRPWSETSLMLDVFTEESGRVRLVAKGARSKRS
                     TLKGALQPFTPLLLRFGGRGEVKTLRSAEAVSLALPLSGITLYSGLYINELLSRVLEY
                     ETRFSELFFDYLHCIQSLAGATGTPEPALRRFELALLGHLGYGVNFTHCAGSGEPVDD
                     TMTYRYREEKGFIASVVIDNKTFTGRQLKALNAREFPDADTLRAAKRFTRMALKPYLG
                     GKPLKSRELFRQFMPKRTVKTHYE"
     gene            24446..25177
                     /gene="pdxJ"
                     /locus_tag="IRB70_000143"
     CDS             24446..25177
                     /gene="pdxJ"
                     /locus_tag="IRB70_000143"
                     /EC_number="2.6.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 5'-phosphate synthase"
                     /protein_id="HBC0630105.1"
                     /translation="MAELLLGVNIDHIATLRNARGTAYPDPVQAAFIAEQAGADGITV
                     HLREDRRHITDRDVRILRQTLDTRMNLEMAVTEEMLAIAVETKPHFCCLVPEKRQEVT
                     TEGGLDVAGQREKMRDACKHLAEAGIQVSLFIDADEEQIKAAAEVGAPFIEIHTGCYA
                     DAKTDAEQAQELARIAKAATFAASLGLKVNAGHGLTYHNVKAIAAIPEMHELNIGHAI
                     IGRAVMTGLKDAVAEMKRLMLEARG"
     gene            25177..25557
                     /locus_tag="IRB70_000144"
     CDS             25177..25557
                     /locus_tag="IRB70_000144"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBC0630106.1"
                     /translation="MAILGLGTDIVEIARIESVIARSGERLARRVLSDNEWAIWKTHH
                     QPVRFLAKRFAVKEAAAKAFGTGIRNGLAFNQFEVFNDELGKPRLRLWGEALKLAEKL
                     GVVNMHVTLADERHYACATVIIES"
     gene            25979..26059
                     /gene="shoB"
                     /locus_tag="IRB70_000145"
     CDS             25979..26059
                     /gene="shoB"
                     /locus_tag="IRB70_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin ShoB"
                     /protein_id="HBC0630107.1"
                     /translation="MTDCRYLIKRVIKIIIAVLQLLLLFL"
     gene            complement(26253..26513)
                     /gene="yfhL"
                     /locus_tag="IRB70_000146"
     CDS             complement(26253..26513)
                     /gene="yfhL"
                     /locus_tag="IRB70_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster ferredoxin YfhL"
                     /protein_id="HBC0630108.1"
                     /translation="MALLITKKCINCDMCEPECPNEAISMGDHIYEINSDKCTECVGH
                     YETPTCQKVCPIPNTIVKDPQHVETEEQLWDKFVLMHHADKI"
     gene            complement(26569..27417)
                     /locus_tag="IRB70_000147"
     CDS             complement(26569..27417)
                     /locus_tag="IRB70_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417056.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBC0630109.1"
                     /translation="MNGLLRIRQRYQGLAQSDKKLADYLLLQPDTARHLSSQQLANEA
                     GVSQSSVVKFAQKLGYKGFPALKLALSEALASQPESPSVPIHNQIRGDDPLRLVGEKL
                     IKENTAAMYATLNVNSEEKLHECVAMLRSARRIILTGIGASGLVAQNFAWKLMKIGFN
                     AAAVRDMHALLATVQASSPDDLLLAISYTGVRRELNLAADEMLRVGGKVLAITGFTPN
                     ALQQRASHCLYTIAEEQATNSASISACHAQGMLTDLLFIALIQQDLELAPERIRHSEA
                     LVKKLV"
     gene            27626..28261
                     /gene="yfhb"
                     /locus_tag="IRB70_000148"
     CDS             27626..28261
                     /gene="yfhb"
                     /locus_tag="IRB70_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311453.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase C"
                     /protein_id="HBC0630110.1"
                     /translation="MATHERRVVFFDLDGTLHQQDMFGSFLRYLLRRQPLNALLVLPL
                     LPIIAIALLIKGRAARWPMSLLLWGCTFGHNEARLQALQADFVRWFRDNVTAFPLVQE
                     RLTTYLLSSDADIWLITGSPQPLVEAVYFDTPWLPRVNLIASQIQRGYGGWVLTMRCL
                     GHEKVAQLERKIGTPLRLYSGYSDSNQDNPLLYFCQHRWRVTPRGELQQLE"
     gene            28286..28822
                     /gene="tadA"
                     /locus_tag="IRB70_000149"
     CDS             28286..28822
                     /gene="tadA"
                     /locus_tag="IRB70_000149"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBC0630111.1"
                     /translation="MRRAFITGVFFLSEVEFSHEYWMRHAMTLAKRAWDEREVPVGAV
                     LVHNNRVIGEGWNRPIGRHDPTAHAEIMALRQGGLVMQNYRLIDATLYVTLEPCVMCA
                     GAMIHSRIGRVVFGARDAKTGAAGSLMDVLHHPGMNHRVEITEGILADECAALLSDFF
                     RMRRQEIKAQKKAQSSTD"
     gene            complement(28819..30375)
                     /gene="mltF"
                     /locus_tag="IRB70_000150"
     CDS             complement(28819..30375)
                     /gene="mltF"
                     /locus_tag="IRB70_000150"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417053.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltF"
                     /protein_id="HBC0630112.1"
                     /translation="MKKLKINYLFIGILALLLAVALWPSIPWFGKADNRIAAIQARGE
                     LRVSTIHTPLTYNEINGKPFGLDYELAKQFADYLGVKLKVTVRQNISQLFDDLDNGNA
                     DLLAAGLVYNSERVKNYQPGPTYYSVSQQLVYKVGQYRPRTLGNLTAEQLTVAPGHVV
                     VNDLQTLKDTKFPELSWKVDDKKGSAELMEDVIEGKLDYTIADSVAISLFQRVHPELA
                     VALDITDEQPVTWFSPLDGDNTLSAALLDFFNEMNEDGTLARIEEKYLGHGDDFDYVD
                     TRTFLRAVDAVLPQLKPLFEKYAEEIDWRLLAAIAYQESHWDAQATSPTGVRGMMMLT
                     KNTAQSLGITDRTDAEQSISGGVRYLQDMMSKVPESVPENERIWFALAAYNMGYAHML
                     DARALTAKTKGNPDSWADVKQRLPLLSQKPYYSKLTYGYARGHEAYAYVENIRKYQIS
                     LVGYLQEKEKQATEAAMQLAQDYPAVSPTELGKEKFPFLSFLSQSSSNYLTHSPSLLF
                     SRKGSEEKQN"
     gene            30634..34521
                     /gene="purL"
                     /locus_tag="IRB70_000151"
                     /gene_synonym="purI"
     CDS             30634..34521
                     /gene="purL"
                     /locus_tag="IRB70_000151"
                     /gene_synonym="purI"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase"
                     /protein_id="HBC0630113.1"
                     /translation="MMEILRGSPALSAFRINKLLARFQAARLPVHNIYAEYVHFADLN
                     APLNDDEHAQLERLLKYGPALASHAPQGKLLLVTPRPGTISPWSSKATDIAHNCGLQQ
                     VNRLERGVAYYIEAGTLTNEQWQQVTAELHDRMMETVFFALDDAEQLFAHHQPTPVTS
                     IDLLGQGRQALIDANLRLGLALAEDEIDYLQDAFTKLGRNPNDIELYMFAQANSEHCR
                     HKIFNADWIIDGEQQPKSLFKMIKNTFETTPDHVLSAYKDNAAVMEGSEVGRYFADHE
                     TGRYDFHQEPAHILMKVETHNHPTAISPWPGAATGSGGEIRDEGATGRGAKPKAGLVG
                     FSVSNLRIPGFEQPWEEDFGKPERIVTALDIMTEGPLGGAAFNNEFGRPALNGYFRTY
                     EEKVNSHNGEELRGYHKPIMLAGGIGNIRADHVQKGEINVGAKLVVLGGPAMNIGLGG
                     GAASSMASGQSDADLDFASVQRDNPEMERRCQEVIDRCWQLGDANPILFIHDVGAGGL
                     SNAMPELVSDGGRGGKFELRDILSDEPGMSPLEIWCNESQERYVLAVAADQLPLFDEL
                     CKRERAPYAVIGEATEELHLSLHDRHFDNQPIDLPLDVLLGKTPKMTREVQTLKAKGD
                     ALVREGITIADAVKRVLHLPTVAEKTFLVTIGDRSVTGMVARDQMVGPWQVPVANCAV
                     TTASLDSYYGEAMAIGERAPVALLDFAASARLAVGEALTNIAATQIGDIKRIKLSANW
                     MAAAGHPGEDAGLYEAVKAVGEELCPALGLTIPVGKDSMSMKTRWQEGNEEREMTSPL
                     SLVISAFARVEDVRHTITPQLSTEDNALLLIDLGKGNNALGATALAQVYRQLGDKPAD
                     VRDVAQLKGFYDAIQALVAQRKLLAYHDRSDGGLLVTLAEMAFAGHCGIDADIASLGD
                     DRLAALFNEELGAVIQVRAADREAVESVLAQHGLADCVHYVGQAVSGDHFVITANGQT
                     VFSESRTTLRVWWAETTWQMQRLRDNPECADQEHQAKSNDADPGLNVKLSFDINEDVA
                     APYIATGARPKVAVLREQGVNSHVEMAAAFHRAGFDAIDVHMSDLLAGRTGLEDFHAL
                     VACGGFSYGDVLGAGEGWAKSILFNDRVRDEFATFFHRPQTLALGVCNGCQMMSNLRE
                     LIPGSELWPRFVRNTSDRFEARFSLVEVTQSPSLLLQGMVGSQMPIAVSHGEGRVEVR
                     DAAHLAALESKGLVALRYVDNFGKVTETYPANPNGSPNGITAVTTESGRVTIMMPHPE
                     RVFRTVSNSWHPENWGEDGPWMRIFRNARKQLG"
     gene            35078..36505
                     /gene="qseE"
                     /locus_tag="IRB70_000152"
     CDS             35078..36505
                     /gene="qseE"
                     /locus_tag="IRB70_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417051.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two component system sensor histidine kinase
                     QseE/GlrK"
                     /protein_id="HBC0630114.1"
                     /translation="MKRWPVFPRSLRQLVMLAFLLILLPLLVLAWQAWQSLNALSDQA
                     ALVNRTTLIDARRSEAMTNAALEMERSYRQYCVLDDPTLAKVYQSQRKRYSEMLDAHA
                     GVLPDDKLYQALRQDLNNLAQLQCNNSGPDAAAAARLEAFASANTEMVQATRTVVFSR
                     GQQLQREIAERGQYFGWQSLVLFLVSLVMVLLFTRMIIGPVKNIERMINRLGEGRSLG
                     NSVSFSGPSELRSVGQRILWLSERLSWLESQRHQFLRHLSHELKTPLASMREGTELLA
                     DQVVGPLTPEQKEVVSILDSSSRNLQKLIEQLLDYNRKQADSAVELENVELAPLVETV
                     VSAHSLPARAKMMHTDVDLKATACLAEPMLLMSVLDNLYSNAVHYGAESGNICLRSSL
                     HGARVYIDVINTGTPIPQEERAMIFEPFFQGSHQRKGAVKGSGLGLSIARDCIRRMQG
                     ELYLVDESGQDVCFRIELPSSKNTK"
     gene            36670..37383
                     /gene="qseG"
                     /locus_tag="IRB70_000153"
     CDS             36670..37383
                     /gene="qseG"
                     /locus_tag="IRB70_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system QseEF-associated
                     lipoprotein QseG"
                     /protein_id="HBC0630115.1"
                     /translation="MRHIFQRLLPRRLWLAGLPCLALLGCVQSHNKPAIDTPAEEKIP
                     VYQLADYLSTECSDIWALQGKSTETNPLYWLRAMDCADRLMPAQSRQQARQYDDGSWQ
                     NTFKQGILLADAKITPYERRQLVARIDALSTEIPAQVRPLYQLWRDGQALQLQLAEER
                     QRYSKLQQSSDSELDTLRQQHHVLQQQLELTTRKLENLTDIERQLSTRKPAGNFSPDT
                     PHESEKPAPSTDEVTPDEP"
     gene            37373..38707
                     /gene="glrR"
                     /locus_tag="IRB70_000154"
     CDS             37373..38707
                     /gene="glrR"
                     /locus_tag="IRB70_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator GlrR"
                     /protein_id="HBC0630116.1"
                     /translation="MSHKPAHLLLVDDDPGLLKLLGLRLTSEGYSVVTAESGAEGLRV
                     LNREKVDLVISDLRMDEMDGMQLFAEIQKVQPGMPVIILTAHGSIPDAVAATQQGVFS
                     FLTKPVDKDALYQAIDDALEQSAPATDERWREAIVTRSPLMLRLLEQARLVAQSDVSV
                     LINGQSGTGKEIFAQAIHNASPRNSKPFIAINCGALPEQLLESELFGHARGAFTGAVS
                     NREGLFQAAEGGTLFLDEIGDMPAPLQVKLLRVLQERKVRPLGSNRDIDIDVRIISAT
                     HRDLPKAMARGEFREDLYYRLNVVSLKIPALAERTEDIPLLANHLLRQAAERHKPFVR
                     AFSTDAMKRLMTASWPGNVRQLVNVIEQCVALTSSPVISDALVEQALEGENTALPTFV
                     EARNQFELNYLRKLLQITKGNVTHAARMAGRNRTEFYKLLSRHELDANDFKE"
     gene            38768..39106
                     /gene="glnB"
                     /locus_tag="IRB70_000155"
     CDS             38768..39106
                     /gene="glnB"
                     /locus_tag="IRB70_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017373484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulatory protein P-II"
                     /protein_id="HBC0630117.1"
                     /translation="MKKIDAIIKPFKLDDVREALAEVGITGMTVTEVKGFGRQKGHTE
                     LYRGAEYMVDFLPKVKIEIVVPDDIVDTCVDTIIRTAQTGKIGDGKIFVFDVARVIRI
                     RTGEEDDAAI"
     gene            complement(39151..40341)
                     /gene="hmpA"
                     /locus_tag="IRB70_000156"
     CDS             complement(39151..40341)
                     /gene="hmpA"
                     /locus_tag="IRB70_000156"
                     /EC_number="1.14.12.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NO-inducible flavohemoprotein"
                     /protein_id="HBC0630118.1"
                     /translation="MLDAQTIATVKATIPLLVETGPKLTAHFYDRMFTHNPELKEIFN
                     MSNQRNGDQREALFNAIAAYASNIENLPALLPAVEKIAQKHTSFQIKPEQYNIVGEHL
                     LATLDEMFSPGQEVLDAWGKAYGVLANVFINREAEIYNENASKAGGWEGTRDFRIVAK
                     TPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKPDGKGYR
                     IAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMAVADDTPVTLISAGVGQTPMLA
                     MLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQALPRFTAHTWYRQPSEADRAK
                     GQFDSEGLMDLSKLEGAFSDPTMQFYLCGPVGFMQFAAKQLVDLGVKQENIHYECFGP
                     HKVL"
     gene            40669..41922
                     /gene="glyA"
                     /locus_tag="IRB70_000157"
     CDS             40669..41922
                     /gene="glyA"
                     /locus_tag="IRB70_000157"
                     /EC_number="2.1.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBC0630119.1"
                     /translation="MLKREMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVM
                     QAQGSQLTNKYAEGYPGKRYYGGCEYVDIVEQLAIDRAKELFGADYANVQPHSGSQAN
                     FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEK
                     QAKEHKPKMIIGGFSAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP
                     HAHVVTTTTHKTLAGPRGGLILAKGGSEELYKKLNSAVFPGGQGGPLMHVIAGKAVAL
                     KEAMEPEFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEAD
                     AALGRANITVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDS
                     INDEAVIERIKGKVLDICARYPVYA"
     gene            complement(41986..43179)
                     /locus_tag="IRB70_000158"
     CDS             complement(41986..43179)
                     /locus_tag="IRB70_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBC0630120.1"
                     /translation="MRACINNQQIRHHNKCVILELLYRQKRANKSTLARLAQISIPAV
                     SNILQELESEKRVVNIDDESQTRGHSSGTWLIAPEGDWTLCLNVTPTSIECQVANACL
                     SPKGEFERFQIDAPTPQALLSEIEKCWHRHRKLWPDRTINLALAIHGQVDPVTGVSQT
                     MPQAPWTTPVEVKYLLEEKLGIRVMVDNDCVMLALAEKWQNNSQERDFCVINVDYGIG
                     SSFVINEQIYRGSLYGSGQIGHTIVNPDGVVCDCGRYGCLETVASLSALKKQARVWLK
                     SQPVNTQLDPEKLTTAQLIAAWQSGEPWITSWVDRSANAIGLSLYNFLNILNINQIWL
                     YGRSCAFGENWLNTIIRQTGFNPFDRDEGPSVKATQIGFGQLSRAQQVLGIGYLYVEA
                     QLRQI"
     gene            43297..46578
                     /locus_tag="IRB70_000159"
     CDS             43297..46578
                     /locus_tag="IRB70_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5107 domain-containing protein"
                     /protein_id="HBC0630121.1"
                     /translation="MTPVKVWQERVEIPTYETGPQDIHPMFLENRVYQGSSGAVYPYG
                     VTDTLSEQKTLKSWQAVWLENDYIKVMILPELGGRVHRAWDKVKQRDFVYHNEVIKPA
                     LVGLLGPWISGGIEFNWPQHHRPTTFMPVDFTLEAHEDGAQTVWVGETEPMHGLQVMT
                     GFTLRPDRAALEIASRVYNGNATPRHFLWWANPAVKGGEGHQSVFPPDVTAVFDHGKR
                     AVSAFPIATGTYYKVDYSAGVDISRYKNVPVPTSYMAEKSQYDFVGAWCHDEDGGLLH
                     VANHHIAPGKKQWSWGHSEFGQAWDKSLTDNNGPYIELMTGIFADNQPDFTWLDAYEE
                     KRFEQYFLPYHSLGMVQNASRDAVIKLQRSERGIEWGLYAISPLNGYRLAIREIGKCN
                     ALLDDAVALMPATAIQGVLHGINPDRLTIELSDADGNIILSYQEHQPQELPLPDVAKA
                     PLSAQDITSTDEAWFIGQHLEQYHHASRSPFDYYLRGVALDLLDYRCNLALAMLEYNR
                     ADFPQTVAYATQALKRAHALNKNPQCGQASLIRASAYERQGQYQQAEEDFWRAVWSGN
                     SKAGGYYGLARLAARNGHFDAGLDFCQQSLRACPTNQEVLCLHNLLLVLSGRQDNARL
                     QREKLLRDYPLNATLWWLNWFDGRSESALAQWRGLCQGRDVNALMTAGQLINWGMPTL
                     AAEMLNALDCQRTLPLYLQASLLPKAERGELVAKAIDVFPQFVRFPNTLEEVAALESI
                     EECWFARHLLACFYYNKRSYNKAITLWQRCVEMSPEFADGWRGLAIHAWNKQHDYELA
                     ARYLDNAYQLAPQDARLLFERDLLDKLSGATPEKRLARLENNLEIALKRDDMTAELLN
                     LWHLTGQADKAADILATRKFHPWEGGEGKITSQFILNQLLRAWQHLDAREPQQASELL
                     HAALHYPENLSEGRLPGQTDNDIWFWQAICANAQGDETEAMRCLRLAATGDRTINIHS
                     YYNDQPVDYLFWQGMALRLLGEQQIAQQLFSEMKQWAQEMAKTSIEADFFAVSQPDLL
                     SLYGDLQQQHKEKCLMVAMLASAGLGEVAHYESARAELTAINPAWPKAALFTTVMPFI
                     FNYVH"
     gene            46675..47658
                     /locus_tag="IRB70_000160"
     CDS             46675..47658
                     /locus_tag="IRB70_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBC0630122.1"
                     /translation="MPKKMRITRNLLLIATLLGSALFARAADKEMTIGAIYLDTQGYY
                     AGVRQGVQDAAKDSSVQVQLIETNAQGDISKESTFVDTLVARNVDAIILSAVSENGSS
                     RTVRRASEAGIPVICYNTCINQKGVDKYVSAYLVGDPLEFGKKLGNAAADYFIANKID
                     QPKIAVINCEAFEVCVQRRKGFEEVLKSRVPGAQIVANQEGTVLDKAISVGEKLIIST
                     PDLNAIMGESGGATLGAVKAVRNQNQAGKIAVFGSDMTTEIAQELENNQVLKAVVDIS
                     GKKMGNAVFAQTLKVINKQADGEKVIQVPIDLYTKTEDGKQWLATHVDGLP"
     gene            47681..49192
                     /locus_tag="IRB70_000161"
     CDS             47681..49192
                     /locus_tag="IRB70_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBC0630123.1"
                     /translation="MFTATEAVPVAKVVAGNKRYPGVVALDNVNFTLNKGEVRALLGK
                     NGAGKSTLIRMLTGSERPDSGDIWIGETRLEGDEATLTRRAAELGVRAVYQELSLVEG
                     LTVAENLCLGQWPRRNGMIDYLQMAQDAQRCLQALGVDVSPEQLVSTLSPAQKQLVEI
                     ARVMKGEPRVVILDEPTSSLASAEVELVISAVKKMSALGVAVIYVSHRMEEIRRIASC
                     ATVMRDGQVAGDVMLENTSTHHIVSLMLGRDHVDIAPVAPQEIMDQAVLEVRALRHKP
                     KLEDISFTLRRGEVLGIAGLLGAGRSELLKAIVGLETYEQGEIVINGEKITRPDYDDM
                     LKRGIGYTPENRKEAGIIPWLGVDENTVLTNRQKISANGVLQWSTIRRLTEEVMQRMT
                     VKAASSETPIGTLSGGNQQKVVIGRWVYAASQILLLDEPTRGVDIEAKQQIYRIVREL
                     AAEGKSVVFISSEVEELPLVCDRILLLQHGTFSQEFHSPVNVDELMSAILSVH"
     gene            49217..50215
                     /locus_tag="IRB70_000162"
     CDS             49217..50215
                     /locus_tag="IRB70_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0630124.1"
                     /translation="MSASSLPLPQGKSVSLKQFVSRHINEIGLLVVIAILYLVFSLNA
                     PGFISLNNQMNVLRDAATIGIAAWAMTLIIISGEIDVSVGPMVAFVSVCLAFLLQFDV
                     PLAIACLLVLLLGALMGTLAGVLRGVFNVPSFVATLGLWSALRGMGLFMTNALPVPIN
                     ENEVLDWLGGQFLGVPVSALIMMVLFALFVFISRKTAFGRSVFAVGGNATAAQLCGIN
                     VRRVRILIFTLSGLLAAVTGILLAARLGSGNAGAANGLEFDVIAAVVVGGTALSGGRG
                     SLFGTLLGVLVITLIGNGLVLLGINSFFQQVVRGVIIVVAVLANILLTQRSSKAKR"
     gene            50248..51342
                     /locus_tag="IRB70_000163"
     CDS             50248..51342
                     /locus_tag="IRB70_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBC0630125.1"
                     /translation="MKINRIVNEGFMKTMLAAYLPGNSTVDLREVAVPTPGINQVLIK
                     MKSSGICGSDVHYIYHQHRATAAAPDKPLYQGFINGHEPCGQIVAMGLGCHHFKEGDR
                     VLVYHISGCGFCPNCRRGFPISCTGEGKAAYGWQRDGGHAEYLLAEEKDLILLPDALS
                     YEDGAFISCGVGTAYEGILRGEVSGSDNVLVVGLGPVGMMAMMLAKGRGAKRIIGVDM
                     LPERLAMAKQLGVMDHGYLATTEGLPQIIAELTHGGADVALDCSGNAAGRLLALQSTA
                     DWGRVVYIGETGKVEFEVSADLMHHQRRIIGSWVTSLFHMEKCAHDLTDWKLWPRNAI
                     THRFSLEQAGDAYALMASGKCGKVVINFPD"
     gene            51354..52226
                     /locus_tag="IRB70_000164"
     CDS             51354..52226
                     /locus_tag="IRB70_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase"
                     /protein_id="HBC0630126.1"
                     /translation="MTIYTLSHGPLKLDVSDRGGVIEGFWRDATPLLRPGKKSGVATD
                     ASCFPLVPFANRVSGNRFVWQGREYQLQPNVEWDAHYLHGDGWLGEWQCVSRSEDSLC
                     LVYEHRSGVYHYRVSQAFHLTADTLTVTLAVTNQGAETLPFGTGWHPYFPLSPQTRIQ
                     AQASGYWLEREQWLAGEFCEQLPQELDFNQLTPLPRQWVNNGFAGWNGQARIEQPQEG
                     YAIIMETTPPAPCYFIFVSDPAFDKGYAFDFFCLEPMSHAPDDHHRPEGGDLIALAPG
                     ESTTSEMSLRVALL"
     gene            complement(52274..52696)
                     /locus_tag="IRB70_000165"
     CDS             complement(52274..52696)
                     /locus_tag="IRB70_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417038.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HBC0630127.1"
                     /translation="MNTLRYFDFGAARPVLLLIARIAVVLIFIIFGFPKMMGFDGTVQ
                     YMASLGAPMPMLAAIIAVVMEVPAAILIVLGFFTRPLAVLFIFYTLGTAVIGHHYWDM
                     TGDAVGPNMINFWKNVSIAGAFLLLAITGPGAISLDRR"
     gene            complement(52793..53995)
                     /locus_tag="IRB70_000166"
     CDS             complement(52793..53995)
                     /locus_tag="IRB70_000166"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylpropionate dioxygenase ferredoxin
                     reductase subunit"
                     /protein_id="HBC0630128.1"
                     /translation="MKEKTIIIVGGGQAAAMAAASLRQQGFTGELHLFSDEQHLPYER
                     PPLSKSMLLEDSPQLQSVLPAHWWQENNVHLHSGVTIKTLGRDTRELVLTNGESWHWD
                     QLFIATGAAARPLPLLDALGERCFTLRHAGDAARLREVLQPERSVVIVGAGTIGLELA
                     ASATQRGCKVTVIELAATVMGRNAPPPVQRYLLQRHQQAGVRILLNNAIEHVVDGEKV
                     ELTLQSGETLRADVVIYGIGISANDQLAREANLDTANGIVIDEACRTCDPAIFAGGDV
                     AITRLDNGALHRCESWENANDQAQIAASAMLGLPLPRLPPPWFWSDQYSDNLQFIGDM
                     RGDDWLCRGNPETQKAIWFNLQNGVLIGAVTLNQGREIRLIRKWIQSGKTFDAKLLTD
                     EHIALKSL"
     gene            complement(54005..54817)
                     /gene="hcaB"
                     /locus_tag="IRB70_000167"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
     CDS             complement(54005..54817)
                     /gene="hcaB"
                     /locus_tag="IRB70_000167"
                     /gene_synonym="phdD"
                     /gene_synonym="yfhX"
                     /EC_number="1.3.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate-dihydrodiol/cinnamic
                     acid-dihydrodiol dehydrogenase"
                     /protein_id="HBC0630129.1"
                     /translation="MSDLHNESIFITGGGSGLGLALVERFIEEGAQVATLELSAAKVA
                     SLRQRFGEHILAVEGNVTCYTDYQRAIDQILTRSGKLDCFIGNAGIWDHNASLVNTPA
                     ETLETGFHELFNVNVLGYLLGAKACAPALIASEGSMIFTLSNAAWYPGGGGPLYTASK
                     HAATGLIRQLAYELAPKVRVNGVGPCGMASDLRGPQALGQSETSIMQSLTPEKIAAIL
                     PLQFFPQPADFTGPYVMLASRRNNRALSGVMINADAGLAIRGIRHVAAGLDL"
     gene            complement(54814..55134)
                     /locus_tag="IRB70_000168"
     CDS             complement(54814..55134)
                     /locus_tag="IRB70_000168"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-phenylpropionate/cinnamic acid
                     dioxygenase ferredoxin subunit"
                     /protein_id="HBC0630130.1"
                     /translation="MNRIYACPVADVPEGEALRIDTSPVIALFNVGGEFYAINDRCSH
                     GNASMSEGYLEDDATVECPLHAASFCLKTGKALCLPATDPLTTYPVHVEGGDIFIDLP
                     EAQP"
     gene            complement(55134..55652)
                     /locus_tag="IRB70_000169"
     CDS             complement(55134..55652)
                     /locus_tag="IRB70_000169"
                     /EC_number="1.14.12.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate/cinnamic acid dioxygenase
                     subunit beta"
                     /protein_id="HBC0630131.1"
                     /translation="MSAQVSLELHHRISQFLFHEASLLDDWKFRDWLAQLDEEIRYTM
                     RTTVNAQTRDRRKGVQPPTTWIFNDTKDQLERRIARLETGMAWAEEPPSRTRHLISNC
                     QVSETDIPNVFAVRVNYLLYRAQKERDEAFYVGTRFDKVRRLEDDNWRLLERDIVLDQ
                     AVITSHNLSVLF"
     gene            complement(55649..57010)
                     /locus_tag="IRB70_000170"
     CDS             complement(55649..57010)
                     /locus_tag="IRB70_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic ring-hydroxylating dioxygenase subunit
                     alpha"
                     /protein_id="HBC0630132.1"
                     /translation="MTTPSDLNIYQLIDTQNGRVTPRIYTDPDIYQLELERIFGRCWL
                     FLAHESQIPKPGDFFNTYMGEDAVVVVRQKDGSIKAFLNQCRHRAMRVSYADCGNTRA
                     FTCPYHGWSYGINGELIDVPLEPRAYPQGLCKSHWGLNEVPCVESYKGLIFGNWDTSA
                     PGLRDYLGDIAWYLDGMLDRREGGTEIVGGVQKWVINCNWKFPAEQFASDQYHALFSH
                     ASAVQVLGAKDDGSDKRLGDGQTARPVWETAKDALQFGQDGHGSGFFFTEKPDANVWV
                     DGAVSSYYRETYAEAEQRLGEVRALRLAGHNNIFPTLSWLNGTATLRVWHPRGPDQVE
                     VWAFCITDKAASDEVKAAFENSATRAFGPAGFLEQDDSENWCEIQKLLKGHRARNSKL
                     CLEMGLGQEKHRDDGIPGITNYIFSETAARGMYQRWADLLSSESWQEVLDKTAAYQQE
                     VMK"
     gene            57146..58036
                     /gene="hcaR"
                     /locus_tag="IRB70_000171"
     CDS             57146..58036
                     /gene="hcaR"
                     /locus_tag="IRB70_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HcaR"
                     /protein_id="HBC0630133.1"
                     /translation="MELRHLRYFVAVAQALNFTRAAEKLHTSQPSLSSQIRDLENCVG
                     VPLLVRDKRKVALTAAGECFLQDALAILEQAENAKLRARKIVQEDRQLTIGFVPSAEV
                     NLLPKVLPMFRLRQPDTLIELVSLITTEQEEKIRRGELDVGLMRHPVYSPEIDYLELF
                     DEPLVVVLPVDHPLAHEKEITAVQLDGVNFVSTDPAYSGSLAPIVKAWFAQENSQPNI
                     VQVATNILVTMNLVGMGLGVTLIPGYMNNFNTGQVVFRPIAGNVPAIALLMAWKKGEM
                     KPALRDFIAIVQERLACVTA"
     gene            58196..59335
                     /locus_tag="IRB70_000172"
     CDS             58196..59335
                     /locus_tag="IRB70_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phenylpropionate MFS transporter"
                     /protein_id="HBC0630134.1"
                     /translation="MVLQSTRWLALGYFTYFFSYGIFLPFWSVWLKGIGLTPETIGLL
                     LGAGLVARFLGSLLIAPRVSDPSRLISALRVLALLTLLFAVAFWAGAHVAWLMLVMIG
                     FNLFFSPLVPLTDALANTWQKQFPLDYGKVRLWGSVAFVIGSALTGKLVSMFDYRVIL
                     ALLTLGVASMLLGFLIRPTIQPQGASRQQESTGWSAWLALVRQNWRFLACVCLLQGAH
                     AAYYGFSAIYWQAAGYSASAVGYLWSLGVVAEVIIFALSNKLFRRCSARDMLLISAVC
                     GVLRWGIMGATTELLWLIMVQILHCGTFTVCHLAAMRYIAARQGSEVIRLQAVYSAVA
                     MGGSIAIMTVFAGFLYQYLGHGVFWVMALVALPAMFLRPKVVPSC"
     gene            complement(59327..60607)
                     /gene="csiE"
                     /locus_tag="IRB70_000173"
     CDS             complement(59327..60607)
                     /gene="csiE"
                     /locus_tag="IRB70_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary phase inducible protein CsiE"
                     /protein_id="HBC0630135.1"
                     /translation="MMPTLAPPSVLSAPQRRCQILLTLFQPGLTATTATFSELNGVDD
                     DIASLDISETGREILRYHQLTLTTGYDGSYRVEGTVLNQRLCLFHWLRRGFRLCPSFI
                     TSHFTPALKSELKRRGIARNFYDDTNLQALVNLCSRRLQKRFETRDIHFLCLYLQYCL
                     LQHHAGITPQFNPLQRRWAESCLEFQVAQEIGRHWQRRALQPVPPDEPLFMALLFSML
                     RVPDPLRDAHQRDRQLRQSIKRLVNHFRELGNVRFYDEQGLCDQLYTHLAQALNRSLF
                     AIGIDNTLPEEFARLYPRLVRTTRAALAGFESEYGVHLSDEESGLVAVIFGAWLMQEN
                     DLHEKQIILLTGNDSEREAQIEQQLREITLLPLNIKHMSVKAFLQTGAPRGAALIIAP
                     YTMPLPLFSPPLIYTDLTLTTHQQEQIRKMLESA"
     gene            complement(60798..61652)
                     /locus_tag="IRB70_000174"
     CDS             complement(60798..61652)
                     /locus_tag="IRB70_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417029.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBC0630136.1"
                     /translation="MALPVNKRILKILFILFVVAFCVYLVPRVAINFFYYPDDKIYGP
                     DPWSAESVEFTAKDGTRLQGWFIPSSTGPADNAIATIIHAHGNAGNMSAHWPLVSWLP
                     ERNFNVFMFDYRGFGKSKGTPSQAGLLDDTQSAINVVRHRSDVNPQRLVLFGQSIGGA
                     NILDVIGQGDREGIRAVILDSTFASYATIANQMIPGSGYLLDESYSGENYIASVSPIP
                     LLLIHGKADHVIPWQHSEKLYSLAKEPKRLILIPDGEHIDAFSDRHGDVYREQMVDFI
                     LSALNPQN"
     gene            complement(61797..62600)
                     /gene="suhB"
                     /locus_tag="IRB70_000175"
     CDS             complement(61797..62600)
                     /gene="suhB"
                     /locus_tag="IRB70_000175"
                     /EC_number="3.1.3.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000553460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol-1-monophosphatase"
                     /protein_id="HBC0630137.1"
                     /translation="MHPMLNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVD
                     KAAEAVIIDTIRKSYPQHTIITEESGELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVS
                     IAVRIKGRTEVAVVYDPMRNELFTATRGQGAQLNGYRLRGSTARDLDGTILATGFPFK
                     AKQYATTYINIVGKLFNECADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGEL
                     LVREAGGIVSDFTGGHNYMLTGNIVAGNPRVVKAMLANMRDELSDALKR"
     gene            62719..63459
                     /gene="trmJ"
                     /locus_tag="IRB70_000176"
     CDS             62719..63459
                     /gene="trmJ"
                     /locus_tag="IRB70_000176"
                     /EC_number="2.1.1.200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (cytosine(32)/uridine(32)-2'-O)-methyltransferase TrmJ"
                     /protein_id="HBC0630138.1"
                     /translation="MLQNIRIVLVETSHTGNMGSVARAMKTMGLTNLWLVNPLVKPDS
                     QAIALAAGASDVIGNAHIVDTLDEALAGCSLVVGTSARSRTLPWPMLDPRECGLKSVA
                     EAANTPVALVFGRERVGLTNEELQKCHYHVAIAANPEYSSLNLAMAVQVIAYEVRMAW
                     LATQENGEQVEHEETPYPLVDDLERFYGHLEQTLLATGFIRENHPGQVMNKLRRLFTR
                     ARPESQELNILRGILASIEQQNKGNKAE"
     gene            63730..64218
                     /gene="iscR"
                     /locus_tag="IRB70_000177"
     CDS             63730..64218
                     /gene="iscR"
                     /locus_tag="IRB70_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002913993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly transcriptional regulator
                     IscR"
                     /protein_id="HBC0630139.1"
                     /translation="MRLTSKGRYAVTAMLDVALNSEAGPVPLADISERQGISLSYLEQ
                     LFSRLRKNGLVSSVRGPGGGYLLGKDASSIAVGEVISAVDESVDATRCQGKGGCQGGD
                     KCLTHALWRDLSDRLTGFLNNITLGELVNNQEVLDVSGRQHTHDAPRTRTQDAIDVKL
                     RA"
     gene            64330..65544
                     /gene="iscS"
                     /locus_tag="IRB70_000178"
     CDS             64330..65544
                     /gene="iscS"
                     /locus_tag="IRB70_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017459011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBC0630140.1"
                     /translation="MKLPIYLDYSATTPVDPRVAEKMMQFMTMDGTFGNPASRSHRFG
                     WQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAANFYQKKGKHIITSKT
                     EHKAVLDTCRQLEREGFEVTYLAPQRNGIIDLKELEAAMRDDTILVSIMHVNNEIGVV
                     QDIAAIGEMCRARGIIYHVDATQSVGKLPIDLSQLKVDLMSFSGHKIYGPKGIGALYV
                     RRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAKEEMATEMERLRGLRNR
                     LWNGIKDIEEVYLNGDLEHGAPNILNVSFNYVEGESLIMALKDLAVSSGSACTSASLE
                     PSYVLRALGLNDELAHSSIRFSLGRFTTEEEIDYTIELVRKSIGRLRDLSPLWEMYKQ
                     GVDLNSIEWAHH"
     gene            65572..65958
                     /gene="iscU"
                     /locus_tag="IRB70_000179"
     CDS             65572..65958
                     /gene="iscU"
                     /locus_tag="IRB70_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold IscU"
                     /protein_id="HBC0630141.1"
                     /translation="MAYSEKVIDHYENPRNVGSFDNNDENVGSGMVGAPACGDVMKLQ
                     IKVNDEGIIEDARFKTYGCGSAIASSSLVTEWVKGKSLDEAQAIKNTDIAEELELPPV
                     KIHCSILAEDAIKAAIADYKSKREAK"
     gene            65975..66298
                     /gene="iscA"
                     /locus_tag="IRB70_000180"
     CDS             65975..66298
                     /gene="iscA"
                     /locus_tag="IRB70_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster assembly protein IscA"
                     /protein_id="HBC0630142.1"
                     /translation="MSITLSDSAAARVNTFLANRGKGFGLRLGVRTSGCSGMAYVLEF
                     VDEPTPEDIVFEDKGVKVVVDGKSLQFLDGTQLDFVKEGLNEGFKFTNPNVKDECGCG
                     ESFHV"
     gene            66394..66909
                     /gene="hscB"
                     /locus_tag="IRB70_000181"
     CDS             66394..66909
                     /gene="hscB"
                     /locus_tag="IRB70_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone HscB"
                     /protein_id="HBC0630143.1"
                     /translation="MDYFTLFGLPARYQLDTQALSLRFQDLQRQYHPDKFASGSQAEQ
                     LAAVQQSATINQAWQTLRHPLMRAEYLLSLHGFDLASEQHTVRDTAFLMEQLELREEL
                     DEIEQAKDEARLESFIKRVKKMFDTRHQLMVEQLDNETWDAAADTVRKLRFLDKLRSS
                     AEQLEEKLLDF"
     gene            66926..68776
                     /gene="hscA"
                     /locus_tag="IRB70_000182"
     CDS             66926..68776
                     /gene="hscA"
                     /locus_tag="IRB70_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S protein assembly chaperone HscA"
                     /protein_id="HBC0630144.1"
                     /translation="MALLQISEPGLSAAPHQRRLAAGIDLGTTNSLVATVRSGQAETL
                     ADHEGRHLLPSVVHYQQQGHSVGYDARTNAALDTANTISSVKRLMGRSLADIQQRYPH
                     LPYQFQASENGLPMIETAAGLLNPVRVSADILKALAARATEALAGELDGVVITVPAYF
                     DDAQRQGTKDAARLAGLHVLRLLNEPTAAAIAYGLDSGQEGVIAVYDLGGGTFDISIL
                     RLSRGVFEVLATGGDSALGGDDFDHLLADYIREQAGIPDRSDNRVQRELLDAAIAAKI
                     ALSDADSVTVNVAGWQGEISREQFNELIAPLVKRTLLACRRALKDAGVEADEVLEVVM
                     VGGSTRVPLVRERVGEFFGRPPLTSIDPDKVVAIGAAIQADILVGNKPDSEMLLLDVI
                     PLSLGLETMGGLVEKVIPRNTTIPVARAQDFTTFKDGQTAMSIHVMQGERELVQDCRS
                     LARFALRGIPALPAGGAHIRVTFQVDADGLLSVTAMEKSTGVEASIQVKPSYGLTDSE
                     IASMIKDSMSYAEQDVKARMLAEQKVEAARVLESLHGALAADAALLSAAERQDIDDAA
                     AHLSEVAQGDDVDAIEQAIKNVDKQTQDFAARRMDQSVRRALKGHSVDEV"
     gene            68778..69113
                     /gene="fdx"
                     /locus_tag="IRB70_000183"
     CDS             68778..69113
                     /gene="fdx"
                     /locus_tag="IRB70_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015683702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISC system 2Fe-2S type ferredoxin"
                     /protein_id="HBC0630145.1"
                     /translation="MPKIVILPHQDLCPDGAVLEANSGETILDVALRNGIEIEHACEK
                     SCACTTCHCIVREGFDSLPESSEQEDDMLDKAWGLEPESRLSCQARVTDEDLVVEIPR
                     YTINHAREH"
     gene            69125..69325
                     /gene="iscX"
                     /locus_tag="IRB70_000184"
     CDS             69125..69325
                     /gene="iscX"
                     /locus_tag="IRB70_000184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004104502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein IscX"
                     /protein_id="HBC0630146.1"
                     /translation="MGLKWTDSREIGEALYDAYPDLDPKTVRFTDMHQWICDLEDFDD
                     DPQASNEKILEAILLVWLDEAE"
     gene            69384..70667
                     /gene="pepB"
                     /locus_tag="IRB70_000185"
     CDS             69384..70667
                     /gene="pepB"
                     /locus_tag="IRB70_000185"
                     /EC_number="3.4.11.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417018.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase PepB"
                     /protein_id="HBC0630147.1"
                     /translation="MTEAMKITLSIQPADARWGEKATYSINNDGITLHLNGADDLGLI
                     QRAARKIDGLGIKHVQLSGEGWDADRCWAFWQGYKAPKGTRKVEWPDLDDAQRQELDN
                     RLMIIDWVRDTINAPAEELGPSQLAQRAVDLISNVAGDCVTYRITKGEDLRDQGYMGL
                     HTVGRGSERSPVLLALDYNPTGDKEAPVYACLVGKGITFDSGGYSIKQTAFMDSMKSD
                     MGGAATVTGALAFAITRGLNKRVKLFLCCADNLISGNAFKLGDIITYRNGKKVEVMNT
                     DAEGRLVLADGLIDASAQKPELIIDAATLTGAAKTALGNDYHALFSFDDALAGRLLAS
                     AAQENEPFWRLPLAEFHRSQLPSNFAELNNTGSAAYPAGASTAAGFLSHFVENYQQGW
                     LHIDCSATYRKAPVEQWSAGATGLGVRTIANLLTA"
     gene            70810..71586
                     /gene="sseB"
                     /locus_tag="IRB70_000186"
     CDS             70810..71586
                     /gene="sseB"
                     /locus_tag="IRB70_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311415.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
                     /protein_id="HBC0630148.1"
                     /translation="MSETKNELEDLLEKAATEPAHRPAFFRTLLESTVWVPGTAAQGE
                     AVVEDSALDLQHWEKEDGTSVIPFFTSLEALQQAVEDEQAFVVMPVRTLFEMTLGETL
                     FLNAKLPTGKEFMPREISLLIGEEGNPLSSQEVLEGGESLILSEVAEPPAQMIDSLTT
                     LFKTIKPVKRAFICSIKENKEAQPNLLIGIEADGDIEEIIQAAGSVATDTLPGDEPID
                     ICQVKKGEKGISHFITEHIVPFYERRWGGFLRDFKQNRII"
     gene            72182..72268
                     /locus_tag="IRB70_000187"
                     /pseudo
     CDS             72182..72268
                     /locus_tag="IRB70_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120414.1"
                     /note="enhances serine sensitivity caused by inhibition of
                     homoserine dehydrogenase I; incomplete; partial in the
                     middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="enhanced serine sensitivity protein SseB"
     gene            complement(72761..73606)
                     /gene="sseA"
                     /locus_tag="IRB70_000188"
     CDS             complement(72761..73606)
                     /gene="sseA"
                     /locus_tag="IRB70_000188"
                     /EC_number="2.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-mercaptopyruvate sulfurtransferase"
                     /protein_id="HBC0630149.1"
                     /translation="MSTTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLN
                     GHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAP
                     RAWWMLRTFGVEKVSILGGGLAGWQRDVLLLEEGAVELPEGEFNATFNPEAVVKVTDV
                     LLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDE
                     LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP
                     VEPLK"
     gene            73813..78771
                     /gene="yfhM"
                     /locus_tag="IRB70_000189"
     CDS             73813..78771
                     /gene="yfhM"
                     /locus_tag="IRB70_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha2-macroglobulin"
                     /protein_id="HBC0630150.1"
                     /translation="MKKLRVAACMLMLALAGCDNNDNAPTAVKKDAPSEVTKAASSEN
                     VSSAKLSAPERQKLAQQSAGKALTLLDLSEVQLDGAATLVLTFSIPLDPDQDFSRVIH
                     VVDKKSGKVDGAWELSDNLKELRLRHLEPKRDLIVTIGKEVKALNNATFSKDDEKTIT
                     TRDIQPSVGFASRGSLLPGKVIEGLPVMALNVNNVDVNFFRVKPESLPAFISQWEYRN
                     SLANWQSDKLLQMADLVYTGRFDLNPARNTREKLLLPLGDIKPLQQAGVYLAVMNQAG
                     RYDYSNPATLFTLSDIGVSAHRYHNRLDIFTQSLENGAAQQGIEVSLLNEKGQTLTQA
                     TSDAQGHVQLENDKNAALLLARKDGQTTLLDLKLPALDLAEFNIAGAPGYSKQFFMFG
                     PRDLYRPGETVILNGLLRDADGKALPDQPIKLDVIKPDGQVLRSVVSQPENGLYHFTW
                     PLDSNAATGMWHIRANTGDNQYRMWDFHVEDFMPERMALNLTGEKTPLTPKDEVKFSV
                     VGYYLYGAPANGNILQGQLFLRPLREAVSALPGFEFGEIAAENLSRTLDEVQLTLDDK
                     GRGEVSTESQWKETHSPLQVIFQGSLLESGGRPVTRRAEQAIWPADALPGIRPQFASK
                     SAYDYRTDSTVKQPIVDEGSNAAFDIVYSDAQGVKKAVSGLQVRLIRERRDYYWNWSE
                     DEGWQSQFDQKDLIENEQTLDLKADETGKVSFPVEWGAYRLEVKAPNEAVSSVRFWAG
                     YSWQDNSDGSGAVRPDRVTLKLDKASYRPGDTIKLHIAAPTAGKGYAMVESSEGPLWW
                     QEIDVPAQGLDLTIPVNKTWNRHDLYLSTLVVRPGDKSRSATPKRAVGVLHLPLGDEN
                     RRLDLALETPAKMRPNQPLTVKIKASTKNGEKPKQVNVLVSAVDSGVLNITGYVTPDP
                     WQAFFGQKRYGADIYDIYGQVIEGQGRLAALRFGGDGDELKRGGKPPVNHVNIVAQQA
                     LPVTLNEQGEGSVALPIGDFNGELRVMAQAWTADDFGSNESKVIVAAPVIAELNMPRF
                     MASGDTSRLTLDITNLTDKPQKLNVALTASGLLELVSDSPAAVELAPGVRTTLFIPVR
                     ALTGFGDGDIQATISGLALPGETVADQHKQWKIGVRPAFPAQTVNYGTALQPGETWAI
                     PADGLQNFSPVTLEGQLLLSGKPPLNIARYIKELKAYPYGCLEQTASGLFPSLYTNAA
                     QLQALGIKGDSDEKRRAAVDIGISRLLQMQRDNGGFALWDKNGDEEYWLTAYVMDFLV
                     RAGEQGYSVPTDAINRGNERLLRYLQDPGMMSIPYADNLKASKFAVQSYAALVLARQQ
                     KAPLGALREIWEHRADAASGLPLLQLGVALKTMGDATRGEEAIALALKTPRNDERKWL
                     GDYGSPLRDNALMLSLLEENKLLPDEQNTLLNTLSQQAFGERWLSTQESNALFLAART
                     VQDLPGKWQAQTSFSAEPLTGEKTLNSNLNSDQLATLQVTNSGDQPLWLRVDASGYPQ
                     SAPLPANNVLQIERHILGTDGKSKSLDSLRSGDLVLVWLQVKASNSVPDALVVDLLPA
                     GLELENQNLANGSASLEQSGGEVQNLLNQMQQASIKHIEFRDDRFVAAVAVDEYQPVT
                     LVYLARAVTPGTYQVPQPMVESMYVPQWRATGAAEDLLIVRP"
     gene            78772..81084
                     /gene="pbpC"
                     /locus_tag="IRB70_000190"
     CDS             78772..81084
                     /gene="pbpC"
                     /locus_tag="IRB70_000190"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417014.1"
                     /note="penicillin-binding protein 1C; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase PbpC"
                     /protein_id="HBC0630151.1"
                     /translation="MPRLLTKRGCWITLAAAPFLLFLAAWGADKLWPLPLHEVNPARV
                     VVAQDGTPLWRFADAEGIWRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARA
                     AWQDLTSGRVISGGSTLTMQVARLLDPHPKTFGGKIRQLWRALQLEWHLSKREILTLY
                     LNRAPFGGTLQGIGAASWAYLGKSPANLSYSEAAMLAVLPQAPSRLRPDRWPERAEAA
                     RNKVLERMAVQGVWSREQVKESREEPIWLAPRQMPQLAPLFSRMMLGKSKSDKIVTTL
                     DAGLQRRLEELAQNWKGRLPPRSSLAMIVVDHTDMRVRGWVGSVDLNDDSRFGHVDMV
                     NAIRSPGSVLKPFVYGLALDEGLIHPASLLQDVPRRTGDYRPGNFDSGFHGPISMSEA
                     LVRSLNLPAVQVLEAYGPKRFAAKLRNAGLPLYLPNGAAPNLSLILGGAGAKLENMAA
                     AYTAFARHGKAGKLRLQPDDPLLERPLMSSGAAWIIRRIMADEAQPLPDGALPRVAPL
                     AWKTGTSYGYRDAWAIGVNARYVIGIWTGRPDGTPVVGQFGFASAVPLLNQVNNILLS
                     RSANLPEDPRPDSVSRGVICWPGGQSLPEGDSNCRRRLATWLLDGSQPPTLLLPEQEG
                     INGIRFPIWLDENGKRVAADCPQARQEMINVWPLPLEPWLPASERRAVRLPPASTICP
                     PYGHDAQLPLQLTGVRDGAIIKRLPGAAEATLPLQSSGGAGERWWFLNGEPLTERGRN
                     VTLHLTDKGDYQLLVMDEVGQIATVKFVMQ"
     gene            81233..81664
                     /gene="ndk"
                     /locus_tag="IRB70_000191"
     CDS             81233..81664
                     /gene="ndk"
                     /locus_tag="IRB70_000191"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBC0630152.1"
                     /translation="MAIERTFSIIKPNAVAKNVIGSIFARFEAAGFKIVGTKMLHLTV
                     EQARGFYAEHDGKPFFDGLVEFMTSGPIVVSVLEGENAVQRHRDLLGATNPANALAGT
                     LRADYADSLTENGTHGSDSVESAAREIAYFFGEGEVCPRTR"
     gene            81814..82968
                     /gene="trmG/rlmN"
                     /locus_tag="IRB70_000192"
     CDS             81814..82968
                     /gene="trmG/rlmN"
                     /locus_tag="IRB70_000192"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (adenosine(37)-C2)-methyltransferase TrmG/ribosomal RNA
                     large subunit methyltransferase RlmN"
                     /protein_id="HBC0630153.1"
                     /translation="MSEQLVTPENVTTKDGKINLLDLNRQQMREFFKDLGEKPFRADQ
                     VMKWMYHYCCDNFDEMTDINKVLRGKLKEVAEIRAPEVVEEQRSSDGTIKWAIAVGDQ
                     RVETVYIPEDDRATLCVSSQVGCALECKFCSTAQQGFNRNLRVSEIIGQVWRAAKIVG
                     AAKVTGQRPITNVVMMGMGEPLLNLNNVVPAMEIMLDDFGFGLSKRRVTLSTSGVVPA
                     LDKLGDMIDVALAISLHAPNDEIRDEIVPINKKYNIETFLAAVRRYLEKSNANQGRVT
                     IEYVMLDHVNDGTEHAHQLAELLKDTPCKINLIPWNPFPGAPYGRSSNSRIDRFSKVL
                     MSYGFTTIVRKTRGDDIDAACGQLAGDVIDRTKRTLRKRMQGEAIDIKAV"
     gene            83253..84263
                     /gene="rodZ"
                     /locus_tag="IRB70_000193"
     CDS             83253..84263
                     /gene="rodZ"
                     /locus_tag="IRB70_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoskeleton protein RodZ"
                     /protein_id="HBC0630154.1"
                     /translation="MNTEATHDQNEALTTGARLRNAREQLGLSQQAVAERLCLKVSTV
                     RDIEEDKAPADLASTFLRGYIRSYARLVHIPEEELLPGLEKQAPLRAAKVAPMQSFSL
                     GKRRKKRDGWLMTFTWLVLFVVIGLSGAWWWQDHKAQQEEITTMADQSSAELNNNQSQ
                     SVPLDTSTTTDQAMATTPTSPVDTTATNTQTPAATTAPSPTVDSQQNAVVPPSQANVD
                     TAATPAPAATTTPDGAAPLPTDQAGVTTPAVDPNALVMNFTADCWLEVTDATGKKLFS
                     GMQRKDGNLNLTGQAPYKLKIGAPAAVQIQYQGKPVDLSRFIRTNQVARLTLNAEQSP
                     AQ"
     gene            84290..85408
                     /gene="ispG"
                     /locus_tag="IRB70_000194"
                     /gene_synonym="gcpE"
     CDS             84290..85408
                     /gene="ispG"
                     /locus_tag="IRB70_000194"
                     /gene_synonym="gcpE"
                     /EC_number="1.17.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin-dependent
                     (E)-4-hydroxy-3-methylbut-2-enyl-diphosphate synthase"
                     /protein_id="HBC0630155.1"
                     /translation="MHNQAPIQRRKSTRIYVGNVPIGDGAPIAVQSMTNTRTTDVEAT
                     VNQIKALERVGADIVRVSVPTMDAAEAFKLIKQQVNVPLVADIHFDYRIALKVAEYGV
                     DCLRINPGNIGNEERIRMVVDCARDKNIPIRIGVNAGSLEKDLQEKYGEPTPQALLES
                     AMRHVDHLDRLNFDQFKVSVKASDVFLAVESYRLLAKQIDQPLHLGITEAGGARSGAV
                     KSAIGLGLLLSEGIGDTLRVSLAADPVEEIKVGFDILKSLRIRSRGINFIACPTCSRQ
                     EFDVIGTVNALEQRLEDIITPMDVSIIGCVVNGPGEALVSTLGVTGGNKKSGLYEDGV
                     RKDRLDNNDMIDQLEARIRAKASQLDEARRIDVQQVEK"
     gene            85519..86793
                     /gene="hisS"
                     /locus_tag="IRB70_000195"
     CDS             85519..86793
                     /gene="hisS"
                     /locus_tag="IRB70_000195"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBC0630156.1"
                     /translation="MAKNIQAIRGMNDYLPGETAIWQRIEGTLKNVLGSYGYSEIRLP
                     IVEQTPLFKRAIGEVTDVVEKEMYTFEDRNGDSLTLRPEGTAGCVRAGIEHGLLYNQE
                     QRLWYIGPMFRHERPQKGRYRQFHQLGCEVFGLQGPDIDAELIMLTARWWRALGISEH
                     VTLELNSIGSLEARANYRDALVAFLEQHKEKLDEDCKRRMYTNPLRVLDSKNPEVQAL
                     LNDAPALGDYLDEESREHFAGLCKLLESAGIAYTVNQRLVRGLDYYNRTVFEWVTNSL
                     GSQGTVCAGGRYDGLVEQLGGRATPAVGFAMGLERLVLLVQAVNPEFKADPVVDIYLV
                     ASGADTQSAAMALAERLRDELPGVKLMTNHGGGNFKKQFARADKWGARVAVVLGESEV
                     ANGTAVVKDLRSGEQTAVAQDSVAAHLRTLLG"
     gene            86811..87431
                     /gene="yfgM"
                     /locus_tag="IRB70_000196"
     CDS             86811..87431
                     /gene="yfgM"
                     /locus_tag="IRB70_000196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ancillary SecYEG translocon subunit YfgM"
                     /protein_id="HBC0630157.1"
                     /translation="MEIYENENDQVEAVKRFFAENGKALAVGVILGVGALIGWRYWNS
                     HQVDSARSASLAYQNAVTAVSEGKPDSIPAAEKFAAENKNTYGALASLELAQQFVDKN
                     ELEKAATQLQQGLADTSDENLKAVINLRLARVQVQLKQADAALKTLDTIKGEGWAAIV
                     ADLRGEALLSKGDKQGARSAWEAGVKSDVTPALSEMMQMKINNLSI"
     gene            87442..88620
                     /gene="bamB"
                     /locus_tag="IRB70_000197"
     CDS             87442..88620
                     /gene="bamB"
                     /locus_tag="IRB70_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamB"
                     /protein_id="HBC0630158.1"
                     /translation="MQLRKLLLPGLLSVTLLSGCSLFNSEEDVVKMSPLPTVENQFTP
                     TTAWSTSVGSGIGNFYSNLHPALADNVVYAADRAGLVKALNADDGKEIWSVSLAEKDG
                     WFSKEPALLSGGVTVSGGHVYIGSEKAQVYALNTSDGTVAWQTKVAGEALSRPVVSDG
                     LVLIHTSNGQLQALNEADGAVKWTVNLDMPSLSLRGESAPATAFGAAVVGGDNGRVSA
                     VLMEQGQMIWQQRISQATGSTEIDRLSDVDTTPVVVNGVVFALAYNGNLTALDLRSGQ
                     IMWKRELGSVNDFIVDGNRIYLVDQNDRVMALTIDGGVTLWTQSDLLHRLLTSPVLYN
                     GNLVVGDSEGYLHWINVEDGRFVAQQKVDSSGFQTEPVAADGKLLIQAKDGTVYSITR
                     "
     gene            88738..90210
                     /gene="der"
                     /locus_tag="IRB70_000198"
     CDS             88738..90210
                     /gene="der"
                     /locus_tag="IRB70_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417006.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBC0630159.1"
                     /translation="MVPVVALVGRPNVGKSTLFNRLTRTRDALVADFPGLTRDRKYGR
                     AEIEGREFICIDTGGIDGTEDGVETRMAEQSLLAIEEADVVLFMVDARAGLMPADEAI
                     AKHLRSREKPTFLVANKTDGLDPDQAVVDFYSLGLGEIYPIAASHGRGVLSLLEHVLL
                     PWMEDLAPQEEVDEDAEYWAQFEAEENGEEEEEDDFDPQSLPIKLAIVGRPNVGKSTL
                     TNRILGEERVVVYDMPGTTRDSIYIPMERDGREYVLIDTAGVRKRGKITDAVEKFSVI
                     KTLQAIEDANVVMLVIDAREGISDQDLSLLGFILNSGRSLVIVVNKWDGLSQEVKEQV
                     KETLDFRLGFIDFARVHFISALHGSGVGNLFESVREAYDSSTRRVGTSMLTRIMTMAV
                     EDHQPPLVRGRRVKLKYAHAGGYNPPIVVIHGNQVKDLPDSYKRYLMNYFRKSLDVMG
                     SPIRIQFKEGENPYANKRNTLTPTQMRKRKRLMKHIKKSK"
     gene            90272..90487
                     /locus_tag="IRB70_000199"
     CDS             90272..90487
                     /locus_tag="IRB70_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBC0630160.1"
                     /translation="MELNCPICKTPLERNGETAHCATCDKDFTVQALCPECHQALQVL
                     KACGAVDYFCQHGHGLISKKRVEFIIA"
     gene            90697..92871
                     /gene="sinH"
                     /locus_tag="IRB70_000200"
     CDS             90697..92871
                     /gene="sinH"
                     /locus_tag="IRB70_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like inverse autotransporter SinH"
                     /protein_id="HBC0630161.1"
                     /translation="MLRWTRCIMLTFISGAAFAAPEINVEHKESLPDLGSQAAQQEEQ
                     TNKGKSLKERGADYVINSATQGFENLTPEALESQARSYLQSQITSTTQSYIEDTLSPY
                     GKVRTNLSLGQGGDLDGSSIDYFVPWYDNQTTVYFSQLSAQRKEDRTIGNIGLGVRHN
                     FDKWLLGGNIFYDYDFTRGHRRLGLGAEAWTDYLKFSGNYYHPLSDWKDSEDFDFYEE
                     RPARGWDIRAEAWLPAYPQLGGKIVFEQYYGNEVALFGTDNLEKDPFAVTLGVKYQPV
                     PLIAVGTDFKAGTGDNTDLSVNATLNYQFGVPLKDQLDPDKVSAAHSLMGSRHDFVER
                     NNFIVLEYKEKDPLDVTLWLKADATNEHPECVIKDTPEEAIGLEKCKWTINALINHHY
                     KIVAASWQAKNNAARTLVMPVIKENTLTEGNNNHWNLVLPAWQYSSDKAEQEKLNTWR
                     VRLALEDEKGNRQNSGVVEITVQQDRKIELIVNNIADVPDENNHSHEASAQADGVDGV
                     VMDLDITDSFGDNTDRNGNVLPQDNLNPQLFDANDKKVTLTNKPCTTETPCVFIAKQD
                     KEKGTVTLSSTLPGTFRWKAKAAPYDDSNYVDVTFLGSDIGGLNAFIYRVGAAKPVNL
                     IGNKEPLPLNSSYRFVLWRDANKDGVFQLSEKLTEEEMKQYDYQWEFTGHSVNGNTGA
                     QANTTNADIEIPATNKDAATKFSAQVTDGVQGYGLQVNYSKK"
     gene            92927..93919
                     /locus_tag="IRB70_000201"
     CDS             92927..93919
                     /locus_tag="IRB70_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630162.1"
                     /translation="MKPHMKRGLTRVALALMLAGYCAVPAAMAEDAAWVASGTTAEFE
                     GTIPWLYREGGNATINSDDADHIKVTSDGKGTRPSGSETDKRLYSGDTITLGWDIGDT
                     EGDIDDGPDGIDAKTTATIKWYSYSDNAGGGKTELIAAAGKTSYKLTDDERGRYIGVE
                     IQPITQTDNPFQGTSLTLLDISTASGGGSDTDNVDPGPVVNQNLKVAIFEKGTSTNLI
                     GGNTAIALNKTYVAKLYSDENQNGKYDAGTDVDVTANYDFAWVFNGNSKQLAAAGGIA
                     NASFDNNDIVIPQTNEQARTSLNGSDRNGKTGLAIPANGDGVQGYTLSIIYKHH"
     gene            94029..102104
                     /locus_tag="IRB70_000202"
     CDS             94029..102104
                     /locus_tag="IRB70_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000109691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RatA-like protein"
                     /protein_id="HBC0630163.1"
                     /translation="MSVCLKPGKIIVLLGMLAAFMLSDFARAGVEWQTYPGSTGEFNG
                     TVPIADSASVPVYQGSVQLDPAASHDVAFSAKPNEFSVDDDAANLIVANPQDSEGDQF
                     STPPALRWENQTPPTVSLVWADAATPDTPLNPQPIANRSFCAQGLAGRSLVAWPQIDT
                     QQSIPLLYLLTSTGYPYEGTVALADQKVTLNIAPAQGDLISVSASGYNETIAAAKTTV
                     GGTITLTVTTKDCQGNVAGNIPFIIKRKDAQNRQGAVNNTAPVVLGSTELTTTATEYR
                     GTSDANGTATITVTQPNGPGVKTPLVASISGIAQTSETAVIFTVLTSPDVAQATMWGH
                     MAETVEAHGYTFSRPKLAAEVSNENATVVDHNETWSTFTWSGADSHCTVLPGMRHFGA
                     LATVIPSTVQTVLGWPMQDDYYWTSLAGTTGQHHAADVSNRAEAQKPDSTTFLVSCVD
                     KPAPDVEPKIVLTPENYDDTAQAMKAKVGEDATMRLTITDNKNNDQPLAYYYFSLHLD
                     DGVNRKNQTDPAWETHPVQIAGGSNLQQVDAHTYEGITDVNGQASLTLSQPGGAGVKT
                     HITARMRSDFTATDAKDVIFTVITSPDSDKARMWGHMRGIIESGSLYKRPLLADETEH
                     ELGSVRENNEDWALYDQNTSMQAECGVGHIPRQSSLESLFSAHPGNAIGTEYGWPTAQ
                     QSYLSAVEQETHSSVNLANGSVDSYSGFKQNYLSCSGNEMVANVEVSTDHDVTVGSKA
                     QAKVGDTIVMTVRTVNGLNNTPVPFTAFTITKGMGYNRLGQVSGFDDPSSGAITMNDT
                     QYGTSQPSMVYAGTTDAQGVATVEIKQPQGVGLRTALSVTPVNSYLPNTVNYNVIFTT
                     PTSPDVSGAQMWGHMDETITVDSSTFTRPKLAAEIASPDGTLTENNEIWARVSQANTS
                     STSKGGCATNMLPRRSQLSALYSANSGNAVQTTHGWPTQRQPYWSSSPADVTPHFFTI
                     ALNDGAQAIGGNTPVYVSCLTTANKPASSITLEVVDKAQWNAGNNAATLKKGETLQVK
                     VTVKDAQGNALADMPFTLSRGDGYTRSGEKHIAGSGDALVAPVVVNGGLADETTLNDT
                     ATVYTAMTGSDGSKILNITRPDTHGTKTALTATLYSDATKKDSLDTIFTVVTSPDSSQ
                     AKMWGHMPETVTAEDGTVFKRPRLLKELSSQTGRTSTLEDNENWALFNINYASSSTTY
                     SGCGTNYIPTQAGLTSLFANNAGNTMKTVQGWPVATRYLSNTSDNGSMEQRNYKAVDL
                     SNGTSAAVSSTALQLLTCQTTPVTTVSQILLEAADPATLDTTYNVVKAKKGEESVVRV
                     TTKDAQGNLVGNTAFILTRANSVSRANASATMSVGSLTVTDAWGNTRNNFQSTSETIY
                     GVTGADGSTTLTLKQDNSTGLRTDLTAKLDTSSSVKATLPVVFTVVTSPDSPKANFWG
                     HMAETVAASDGSVYKRPLLLAELANTGGRQISSENGESWVRFTWNQSTDPSVSGCGVA
                     YMPTLAGLQALYDANSGNAMSTVQGWPVKATYLTNTPSDTQTGSRYYNVVQLDSGAAS
                     QITTNTGVLQTCRTTPLTAASQITLEAADPAQFVSIDSTLSAVKVQKGDSVPIRISTK
                     DAQGNFVGNTPFALKHANSINRQNVSSSQKVSVTTEVGTTVDTSATTTLYGVTGPDGT
                     TTMTLRQDASTGLRTDFYALLNDTGVSSDTLPVIFTVITSPDTPLAANWGHMAETFTS
                     SEGVTFKRPSLKAELSGGTAITVNNEVWSRLTAAEKVDASKAGCDETYQPLVNDMQGL
                     YADYPNGQLGSVLGLPTSAGYWWAYDMMMVSGNWTNQAFSPVNGQLMQASSSYTAIVM
                     CLVEPHTEAATIELTSTAQDAAKSASNGGRPSAVAKKGETIPLTVTVRDSAGNPMPYA
                     EFTLTRETTLDRSKATVNTSADDLTVTALVPANTNSVLAASGAKLIGTTGSDGKATFE
                     VSQNATTGLATPLTVTLARDTTKAATLDVIYTVITSPDSPSAKFWGHMPDTFTSSTGV
                     TFKRPLLKAETSSGSSISSNGEVWSYMSNAQNLTSTDCPLENQPRSNELLDLYSDHPN
                     GTLMTDLGLPVYAGNWWAYDMVMLSGTSWTYQLISLKDGTITQKGTTSALMLCLAQPH
                     PAGVSVTLTSSAQDDARTTSNGGRPSASAKKGNSIPIVVTVKDRDGNPLAGEAVTLKR
                     DSALSRSGTIVGTPANEIKLTELTPVSATFPLVSNGTQWLGFTGSDGTATFNVEQPDT
                     VGLAIPFNAILARDTARVSTLDLIFTVLTSPDAALATYWGHMPDTVTAENGAVFERPK
                     LWKELPSTSGVSQITNSNEAWPVFNATQRADSNLSPCEAARRPLSDDLEALYTRYPGN
                     TITAQIGWPTQYAWWAVDNWEGGSNPQAVSLVNGSRGQYNPAHQACLVNPRASVSSVT
                     LTSTALDDATQAATVKKGDAAPIVVTVKDSAGKPVPNIAFILKRGEAVPRNSGATLYG
                     DVDAMDDLTVQPSSGAAVTLADSGNTIDGVTGADGTASFTVRQDNTPGYKTPLTVTLT
                     DNATITATLDTIFTVPTSPNVATAYFWGHMADTATVSGKTLHRPLLKSELPSGATAAA
                     TPDVNNETWALAHVMDSSKWDVAQQCGSMNNVPSSAELQTLHSGFSTLGWPSSISFPY
                     LSTDKAGSFYCGVDEGSGSLNCGIQPAKTPGFATCFQ"
     gene            complement(102158..103525)
                     /gene="xseA"
                     /locus_tag="IRB70_000203"
     CDS             complement(102158..103525)
                     /gene="xseA"
                     /locus_tag="IRB70_000203"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBC0630164.1"
                     /translation="MLPSQSPAIFTVSRLNQTVRLLLEHEMGQVWISGEISNFTQPAS
                     GHWYFTLKDDTAQVRCAMFRNSNRRVTFRPQHGQQVLVRANITLYEPRGDYQIIVESM
                     QPAGEGLLQQKYEQLKAKLQAEGLFDQQLKKPLPSPAHCVGVITSKTGAALHDILHVL
                     KRRDPSLPVIIYPTAVQGDDAPGQIVRAIELANQRNECDVLIVGRGGGSLEDLWSFND
                     ERVARAIFASRIPVVSAVGHETDVTIADFVADLRAPTPSAAAEVVSRNQQELLRQVQS
                     ARQRLEMAMDYYLANRTRRFTQIHHRLQQQHPQLRLARQQTMLERLQKRMSFALENQL
                     KRAGQQQQRLTQRLNQQNPQPKIHRAQTRIQQLEYRLAETLRAQLSATRERFGNAVTH
                     LEAVSPLSTLARGYSVTSAADGAVLKQVKQVKVGETLTTRLGDGVVISEVSAVTKSRK
                     PRKKA"
     gene            103687..105153
                     /gene="guaB"
                     /locus_tag="IRB70_000204"
     CDS             103687..105153
                     /gene="guaB"
                     /locus_tag="IRB70_000204"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004151980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBC0630165.1"
                     /translation="MLRIAKEALTFDDVLLVPAHSTVLPNTADLSTQLTKTIRLNIPM
                     LSAAMDTVTEARLAIALAQEGGIGFIHKNMSIERQAEEVRRVKKHESGVVTDPQTVLP
                     TTTLREVKELTERNGFAGYPVVTEENELVGIITGRDVRFVTDLNQPVSVYMTPKERLV
                     TVREGEAREVVLAKMHEKRVEKALVVDDEFHLIGMITVKDFQKAERKPNACKDEQGRL
                     RVGAAVGAGAGNEERVDALVAAGVDVLLIDSSHGHSEGVLQRIRETRAKYPDLQIIGG
                     NVATAAGARALAEAGCSAVKVGIGPGSICTTRIVTGVGVPQITAVADAVEALEGTGIP
                     VIADGGIRFSGDIAKAIAAGASAVMVGSMLAGTEESPGEIELYQGRSYKSYRGMGSLG
                     AMSKGSSDRYFQSDNAADKLVPEGIEGRVAYKGRLKEIIHQQMGGLRSCMGLTGCGTI
                     DELRTKAEFVRISGAGIQESHVHDVTITKESPNYRLGS"
     gene            105222..106799
                     /gene="guaA"
                     /locus_tag="IRB70_000205"
     CDS             105222..106799
                     /gene="guaA"
                     /locus_tag="IRB70_000205"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBC0630166.1"
                     /translation="MTENIHKHRILILDFGSQYTQLVARRVRELGVYCELWAWDVTEA
                     QIRDFNPSGIILSGGPESTTEENSPRAPQYVFEAGVPVFGVCYGMQTMAMQLGGHVEA
                     SNEREFGYAQVEVVNDSALVRGIEDALTADGKPLLDVWMSHGDKVTAIPSDFITVAST
                     ESCPFAIMANEEKRFYGVQFHPEVTHTRQGMRMLERFVRDICQCEALWTPAKIIDDAV
                     ARIREQVGDDKVILGLSGGVDSSVTAMLLHRAIGKNLTCVFVDNGLLRLNEAEQVLDM
                     FGDHFGLNIVHVPAEDRFLSALAGENDPEAKRKIIGRVFVEVFDEEALKLEDVKWLAQ
                     GTIYPDVIESAASATGKAHVIKSHHNVGGLPKEMKMGLVEPLKELFKDEVRKIGLELG
                     LPYDMLYRHPFPGPGLGVRVLGEVKKEYCDLLRRADAIFIEELRKADLYDKVSQAFTV
                     FLPVRSVGVMGDGRKYDWVVSLRAVETIDFMTAHWAHLPYDFLGRVSNRIINEVNGIS
                     RVVYDISGKPPATIEWE"
     gene            106992..108242
                     /locus_tag="IRB70_000206"
     CDS             106992..108242
                     /locus_tag="IRB70_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBC0630167.1"
                     /translation="MLTDTKLKNLKPQDKLYKVSDRDGLYVAVLTSGTVSFRYDYRIN
                     GRRETLVIGQYGRDGISLAEAREELIAAKKLLKAGQSPAAAKRDGIKKIRGAETFAVH
                     TDSYMKHVILADSTRAMKQAVIDRDILPVLGNKMMAEITTSMVRDLCDRIVERGGRAT
                     AVQAREIISSVYRHANDRGHGLFNPAADIKPSSIAIFKPRERTLTPEEIGLFFRTLDA
                     IGAMGTMKMALKLVLITMVRKGEFTNATWDEIDFKKWTWTIPSDRMKGSRAHVIYLPK
                     QAQDILVGLQMCAGGSEYLVPGRYNFRKPLSNAALNSLIDRTVKIINEDGEHIQGFTV
                     HDMRRTASTLLHEAGYPSDWIEKALAHEQKGVRAVYNKAEYARQRAYMLQQWADMIDS
                     WINGEHTDLIPFSPSKFEKWMAGE"
     gene            complement(108274..108924)
                     /locus_tag="IRB70_000207"
     CDS             complement(108274..108924)
                     /locus_tag="IRB70_000207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor Ant"
                     /protein_id="HBC0630168.1"
                     /translation="MTSQLIPVFNGTISNETALLVNARDLHSFLDVGKRFASWIVERI
                     AEYGFVENQDFMIISQVREKIGRGRPAKDYHLTLDTAKELAMVERNEKGRQVRCYFIE
                     CEKRLRQQETKVEKVLSGFMPAIMEAIKLEDKKEYSAPLKPGYRSLIHSPSGVLGLTE
                     NSLLMNLLNKLQEDGHDVSGAAAELTTMFCYIVGVSKCLRDIQTHAEYINDKAGFF"
     gene            complement(109249..109497)
                     /locus_tag="IRB70_000208"
     CDS             complement(109249..109497)
                     /locus_tag="IRB70_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630169.1"
                     /translation="MKQIMVAHNGVRFEVVMVLTKYRNDEVLQRKETVTYRYKHRSSA
                     VRTLRKITEELKNDPHRVIEVKGNPYKITTSVELRHMQ"
     gene            complement(109494..110144)
                     /locus_tag="IRB70_000209"
     CDS             complement(109494..110144)
                     /locus_tag="IRB70_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine methylase"
                     /protein_id="HBC0630170.1"
                     /translation="MTKKYTLIYADPPWVYRDKAADGNRGAGFKYPVMSVLDICRLPV
                     WDLADENCLLAMWWVPTQPLEALKVVEAWGFRLMTMKGFTWIKCGSRQPDKLVMGMGH
                     MTRANSEDCLFAVKGKLPTRINAGIVQSFTAPRLEHSRKPDIVREKLVQLLGDVSRIE
                     LFARQTSHGFDVWGNQCEDPAVQLHPGYALDIGGLTNAFSNAPLSPTDNQGRERAA"
     gene            complement(110137..110388)
                     /locus_tag="IRB70_000210"
     CDS             complement(110137..110388)
                     /locus_tag="IRB70_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001429704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HBC0630171.1"
                     /translation="MRSPSKIVAVTPAAIEIEKRAIEREKKGQFRIAAHLWLQCMDVA
                     SGDVERARIAVRRDQCITKGNGLRRGDYSGIGCCGVVYD"
     gene            complement(110546..110794)
                     /locus_tag="IRB70_000211"
     CDS             complement(110546..110794)
                     /locus_tag="IRB70_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009485476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family phage regulatory protein"
                     /protein_id="HBC0630172.1"
                     /translation="MKGALGKKELLAVVPLSWSTIDRMERAGEFPKRWYITDKRCAWN
                     RDEVERWLDERQAASPAEFQGKKPPVQQRVYRPVSNAA"
     gene            complement(110844..111785)
                     /locus_tag="IRB70_000212"
     CDS             complement(110844..111785)
                     /locus_tag="IRB70_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001509282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBC0630173.1"
                     /translation="MSNDIANINAPVDTAIAGTAATIFSPDGLNQLMKFAEVMAQSRV
                     TVPAHLAGKPADCMAVAMQAAQWGMNPFAVAQKTHVVNGTLGYEAQLVNAVISTMSPT
                     KDRINYEWFGPWERVIGKFVEKTSKNGNPYIAPGWTLKDEEGCGVRVWATMKGEDQPR
                     VLELMLSQAQVRNSTLWASDPKQQLAYLATKRWSRLHCPDVIMGVYTPDELQETAPRV
                     ERDITPQTTTAAGMNSLINAKPAKKPDEQTRKSDSRDPEEMLMAFTSAAMNYSTVSEL
                     DKAYKYIAQKLSDDDELLAKATDVYSVRREELNETSM"
     gene            complement(111782..112603)
                     /locus_tag="IRB70_000213"
     CDS             complement(111782..112603)
                     /locus_tag="IRB70_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000802265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease-like domain-containing
                     protein"
                     /protein_id="HBC0630174.1"
                     /translation="MKPGIYFDISNEDYHAGDGVSKSQLDMVAKNPALLKWVQAAPED
                     EEKKSALDMGTALHCLLLEPGEFDKRFIVSPKFDRRTKQGKADEEEFLRDVADMGITV
                     LDAEQWRKLELMRDSAMAHPAARWMLEAPGYCEASMYWNDEETGELCRIRPDKWLNEH
                     NVIVDVKKVADMDRFARHIEEFRYHVQDAMYREGAMRVTGQPHGFFFLAVSESIDCGR
                     YPVRVFELDAQDVDAGHALFRRDLNTYHECRINDEWGGVEIIKRPEWARKQDMYI"
     gene            complement(112600..112899)
                     /locus_tag="IRB70_000214"
     CDS             complement(112600..112899)
                     /locus_tag="IRB70_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005028273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630175.1"
                     /translation="MNVNQQKNLQKIMLAFDKDYRLSEQLYDRQVELIESIRLHQLAS
                     TFDVVTVKGVRQEVLEAAKDSPEFEELMDAYRREAMAIIARWDLADQLDGQRDAA"
     gene            complement(112902..113054)
                     /locus_tag="IRB70_000215"
     CDS             complement(112902..113054)
                     /locus_tag="IRB70_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001198620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630176.1"
                     /translation="MQWKIINGWYCVTACGFMSWKFRTLQEGIKWAFVSKEARDVAND
                     NEIWEG"
     gene            complement(113208..113792)
                     /locus_tag="IRB70_000216"
     CDS             complement(113208..113792)
                     /locus_tag="IRB70_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000836290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0630177.1"
                     /translation="MKSIQDVRRQNLNDLIDREFNGVQTRMAEKLGTQANLVNRWALG
                     KKVIGDQVARKIEAAANKPRNWLDIDRSLSQEGFQPVGPSDIGQLAAHNLERWMSESR
                     DLSTQGKLHRASGVAQVTISRLLNNEVSVSISTLENVASAFGRHGYELLIHPHDPATI
                     NYDRSRYALLPETEKAKIESYIEFVINQNEKNKQ"
     gene            113947..114177
                     /locus_tag="IRB70_000217"
     CDS             113947..114177
                     /locus_tag="IRB70_000217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630178.1"
                     /translation="MSDNGHFDFKKHWLALTPDEREAFAQEAGTTSHYIQTHLTGKRK
                     MPGKVLMNGLFKACKTRQWLRSKAELAYFFYS"
     gene            114328..114528
                     /locus_tag="IRB70_000218"
     CDS             114328..114528
                     /locus_tag="IRB70_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000402896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630179.1"
                     /translation="MEIITRIDAAKRGLKRYYTGKTCKHGHDSERWVYNGHCVECTME
                     SNRRIRAEIKQIMINSSPQHSS"
     gene            114544..115359
                     /locus_tag="IRB70_000219"
     CDS             114544..115359
                     /locus_tag="IRB70_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001559621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0630180.1"
                     /translation="MSRHATDWAWETDPGSSSLKLILLSMADRADEYNLCYPSIERLV
                     KDTCLNKKTVQAGLISLMKMGLISDTGERKGATKRVRVFSLNITKNGNIKGNREGGNE
                     PENGNVTENGNIPKNGMLNDPKNGMLNDPKNGIQNQSYNQSFNQERESRTKSGDSVPH
                     DPGANNAVMNNFVPPGGPGQLGKFVMHEQWQPSDDFLRKSSLQGIYLDSLPTAQELAE
                     FRIYWMAEGKAYHQAQWEQKLARRLQISRQKQSTLPDNNVPHWNSPEAWEDFL"
     gene            115356..116141
                     /locus_tag="IRB70_000220"
     CDS             115356..116141
                     /locus_tag="IRB70_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBC0630181.1"
                     /translation="MNNVFTAIQNRDGEALSRMSGYEHQYVNNDNVVNMSAERLVDAL
                     FKQLKQLFPAAVVTNLKTPEQEVAAKQQWIAAFAEGGIRTREQVSAGMRHARASESPF
                     WPSPGQFIKWCKDSKMVLGVTIDDVMAEFHRYSKEKSLYPGGPERFPWRHPVMYWVVC
                     DTRRAMYQRQLSEIEVEKHARRLLDDWAKKVASGQQIPDPVISIQAKPEPMSTPPDTG
                     RDVYHPPGRSFGCMPNAATLGGITPAQWLMEEYRRGKAAGFIK"
BASE COUNT        28024 a        29181 c        31482 g        27480 t
ORIGIN      
        1 ataggccggg tgtgtaagcg cagcgatgcg ttgagctaac cggtactaat gaaccgtgag
       61 gcttaacctt acaacgccga agatgttttg gcggaagaga gaagattttc agcctgatac
      121 agattaaatc agaacgcaga agcggtctga tgaaacagaa tttgcctggc ggccttagcg
      181 cggtggtccc acctgacccc atgccgaact cagaagtgaa acgccgtagc gccgatggta
      241 gtgtggggtc tccccatgcg agagtaggga actgccaggc atcaaattaa gcagaaggcc
      301 atccgtcagg atggcctttt tgcattggtg cagaaaaaaa tgcctgatgc gatgctgcgc
      361 gtcttatact cccacatatg ccagattcag caacggatac ggtttcccca acttgcctac
      421 ttccatacgt gtcctcctta ccagaaattt atccttaagc tcctcaataa ccattttcct
      481 gctaactaaa ttcatggtta aggttgcata atgatacgca acaaatgtat aacatttttt
      541 taccaaaaaa aataaacaac agcgaccgac aaaagcatcg gattacggca ggagacataa
      601 tggcatggct gaaagtactg taacggcaga cagcaaactg acaagtagtg atactcgtcg
      661 ccgcatttgg gcgattgtgg gggcctcttc aggtaatctg gtcgagtggt tcgatttcta
      721 tgtctactcg ttctgttcac tctactttgc ccacatcttc ttcccttccg ggaacacgac
      781 gactcaacta ctacaaacag caggtgtttt tgctgcggga tttctgatgc gcccaatagg
      841 cggttggcta tttggccgca tagccgataa acatggtcgc aaaaaatcga tgctattatc
      901 ggtgtgtatg atgtgtttcg gctcactggt tatcgcctgt ttgccaggct acgaaacaat
      961 cggtacctgg gctccggcat tattgcttct tgctcgttta ttccagggat tatccgttgg
     1021 cggagaatat ggcaccagcg ccacctatat gagtgaagtt gccgttgaag ggcgcaaagg
     1081 tttttacgca tcatttcagt atgtgacgtt gatcggcggg caactgctag ctctactggt
     1141 tgtcgtggtt ttacaacaca ccatggaaga cgctgcactc agagagtggg gatggcgtat
     1201 tcctttcgcg ttaggagctg tgttagctgt tgtggcgttg tggttacgtc gtcagttaga
     1261 tgaaacttca caacaagaaa cgcgcgcttt aaaagaagct ggatctctga aaggattatg
     1321 gcgcaatcgc cgtgcattca tcatggttct cggttttacc gctgcgggct ccctttgttt
     1381 ctataccttc accacttata tgcagaagta tctggtaaat actgcgggaa tgcatgccaa
     1441 cgtggcgagt ggcattatga ctgccgcatt gtttgtattc atgcttattc aaccactcat
     1501 tggcgcgctg tcggataaga ttggtcgccg tacctcaatg ttatgtttcg gttcgctggc
     1561 agccattttt accgttccta ttctctcagc attgcaaaac gtttcctcgc cttatgccgc
     1621 ttttggtctg gtgatgtgtg ccctgctgat agtgagtttt tatacttcaa tcagtggaat
     1681 actgaaggct gaaatgttcc cggcccaggt tcgcgcatta ggtgttggtc tgtcatatgc
     1741 ggtcgccaat gctatatttg gtggttcggc ggagtacgta gcgttgtcgc tgaaatcaat
     1801 aggaatggaa acagccttct tctggtatgt gaccttgatg gccgtggtgg cgtttctggt
     1861 ttctttgatg ctacatcgca aagggaaggg gatgcgtctt tagtgacggg tcagttgcca
     1921 gacggtatag ccggtgcttg caccggcgat atcccaggca aaatccttcc agctccagcc
     1981 gctcccttcg gggcggctat cccaaagctc ttttgacgcc cccaaactga cagagaacat
     2041 caatccaaac atggcactgc gatcccggct catcccctga tgctgtgaat attcatttcc
     2101 ggcggcggaa agcatcgccg aggcgataaa gtgttgagct ttatcctgcc cgctccagct
     2161 atcgttagcc atatggctgc atccagaaag taacaatagc gaacagacaa aaagaatacg
     2221 caaaacgtgg cctccaaaaa acaaaccccg tacaggacgg ggttgtgatt acaggatgcg
     2281 gctaattaat cggtcgatgc ggatacggcg caaacggcgg atgagtttac gaaccttcac
     2341 cggataatcg gcaatacttt gcagatcgcg atagtgctta acgatggtgg tatgctcgcg
     2401 gatcagctcc agttctttct ctcgctgcgg cgcaagctcc agttgtggat cgtggatcaa
     2461 aatggcgttt tccagatcca gacgccaggc gcgcgggttc aggttattgc cggttaccag
     2521 catccactta tcatcaaccc acatcccttt caggtgatag gtgttgtcgt cgtctttcca
     2581 taaccgaacc actaactggt cagtattgac gtaatactgc aaacggctca ggaaacgacg
     2641 cagattgatc tcatagagat aaggcaatgc gccaattatc ttgaaaggtt catcttccgg
     2701 aatgtagaag tcattcgcgg ttttatcacc aacaataatt tcgacctttt tcccttcgcg
     2761 cagcaactgg ataatattgc gcacaaggat tgctggcagg ttgaagtatg gcgtacagat
     2821 ggttagtttc tgctcggcac aaggcataag atggaaaatg gtcttgttca acagactcga
     2881 tttccccagc cccactagcg gcgttacgga aagctgatcg ttgtcggcat cgccctggaa
     2941 atgataagcg gcatcacgca gctcctggcg gaacaggcga atgtcgttct tgatttccgg
     3001 gctttttggc cgattaacat catccagacg attaacgccg cggccattca taatattctg
     3061 tgtaacccat tcaaacataa tgtctgacat cttacggtta cggatcagat gataacggtc
     3121 gtagcgatat ttatcgtgct gatgcaggta aacatcgttc aggctggcac cgctataaag
     3181 tacgctatcg tcgatgataa agcctttaaa gtgcagaaca ccaagggctt cacgggtatt
     3241 gattggaacg ccataaaccg gaacatctac gcccggattt tcctgcgcca tgcggcagta
     3301 ccagtcagcg ttagtgttag atgccgcagc gccaatgcgt ccacgttgtg cacgatgcca
     3361 gtcgaccagc acccgtacat ccagttccgg acgctgcctt ttagcctcat acaacgcgtt
     3421 cagaatgcct ttgccaccgt catcctgttc gagatacagg gcgacaatgc aaatgcgctg
     3481 cttcgcgctg gctatttttt ccagcagcgt ctcccggaag tcggcgggag cgtaaaagaa
     3541 atcgacatca tcaactgatt gagaaatctt gggtagttgg gcaaggtgtt gttgatgttt
     3601 attacgctta aattttgaca acatcacagt gcatttcttc tctgttcatt gaagggtcct
     3661 ctgtgcaatg cagacgacat aagcgggcaa taataacacc agtcccgatt aagtggtcaa
     3721 catttccagt accttactca tgattcctcg cgctgggcaa gatttagcgt aagcccaacg
     3781 atcccctctt cgagctggat atcaacgtta aacccgagct tgcgggccag cgccaccatg
     3841 ccacgattgt ttggcatcgt aataccattc agacgttgca gtccgtgatc tcgcgtatag
     3901 gtaatcaatt tttccattaa gcgtcgacct aagcctaacc ctttgagatc cgagcgaacc
     3961 agcacggcaa attcggcatc gatgttatca gggtcggaga tcgcacgcgt gacgccgagg
     4021 atctcttccg tttgatcaat acgtcgtacc gctacaaatg ccatttcccg atcgtagtcg
     4081 atctgcgtca tgttggctaa atcttcatgg gtaaattcgt tgatctcgct aaagtagcgg
     4141 taataaagat cttctttggt gactcgcgaa atgaactgct gaagttgtgg ctcatcttct
     4201 ggcaaaatcg ggcggaacaa gcagcgttca ccgtttttca attctaccca ctcttccagc
     4261 tgatgcggat aagggcgcac tgccagccgg ctctcgttat cgccttcaaa cggcgcgata
     4321 tccagcgtga catccagcgc ggtaaattca ctgccagaag ccagcaaagg atgaatatcc
     4381 agccgttgaa tttccggaca atcgacaatc aagttggaaa cctgtaccag aagctggctc
     4441 aagcctgcaa catccaaggg gcgtagcgca ctgcgcgcac gaatcttttt acttttgatc
     4501 ccctgaataa ccagatagcg ggccaggttc atgttcagcg gtggtaacgc gacgacggct
     4561 tgatcttcag gacgccactc cacaccgcct tcgcccagca tgatcaacgg cccgaaaacc
     4621 ggatcgtact caaccacaac ccgcaactcc tgagcgccag cacggttagc catactttgc
     4681 accaacaggc cgtggatccg cgcctgcggc caggccattt ttacgcgatc gaaaatagcg
     4741 tttgccgctt gctggacttc attagctgta cgcaggtaga gcatgacgcc ctgaacttcc
     4801 gatttatgtg gaatatccgg cgaacgcaat ttcagcgcca ccggataacc aatctgttcg
     4861 gcaatatgca ccgcttcggt gctatcgttg gcaatccagg tggggagcgt gttcatgcca
     4921 tacgcttgca ggatgggctg aacctcatgg gtatcaagcg acgtagcccc ttcggcaatc
     4981 gcctgttgca acagaagatg cgcttctgcg gtattggagg tcagattgct gggcaacgcc
     5041 ggcgtttcgc gtagttgctt ctgattacgc cggtactcca ccatatgcat aaaagcagtg
     5101 atggttcctt ccggtgtgcg ataggtcggc agcccggctt cactgaataa tcgtcgtgcc
     5161 tcttgcgagg agtactcgcc acaccagttc gtcagcagag aaacatactt gctgcgggga
     5221 tgatgcttta ccgcttcaat taatgcttgc gcgctttctg ttgcgggagc agcggcgctg
     5281 ggcgaatgaa taaccatcag cgcatcaaaa tcctcgctgt ggagcagaat gtccagcgtt
     5341 ttgacataat gctcgctgct ggcgtcatcg cgcagatcga gagggttaga gattgccaca
     5401 tgtccaggca gtgcatcgcg cagtttctgg caggtttctt cgcttagcgt tgccagcttg
     5461 ccattgcgtg accataaggc atccagcgcc agcgcggcag gcgcagcacc gttgctgata
     5521 atcatcaacc ggtcaccacg cagcgggcgc atatggctaa gggtttccac cgccgaaaac
     5581 agttcgtggg tatcctgtac ccgcaacaaa ccggcacgct gaatagccgc atcccacgcc
     5641 ggatccattc ctgccgtggt gttcaacaga cgttgagccg ccgggctacg tccgctttta
     5701 atcaccagaa tcggtttatt gcgcgaggca ctacgggccg ccgaaacaaa gcgtcgcgcg
     5761 tcgcttaact gttcgagata gagcaggatg gcgctggttt tactgtcgcg tgccagatag
     5821 tcgagcaatt catcaacgtc gatatccagg ctgtcgccga gcgcaataaa gtaggaaaag
     5881 cccatctcac gctgttgcgc ccagtcgagg atggtgttgg agacagcagc cgattgcgaa
     5941 ataaacgcca gcttgccgcg tttaatcggc acaggcgaaa agctggcatt cagaccttgc
     6001 cagggagcca gtaaacccag actgtttggt ccaagcaggc gcatgttatg gcgcagggcg
     6061 caggcgcgga gatcttcgtg ttgcgatacc ggggcggaaa gaataatgca ggttttacag
     6121 cctttctcgc cgagctcttc cagaagagca agattacggc tggcattggt acataaaacc
     6181 gcaaggtctg gtgtaaaggg caagctggca atatccggcc aggccaacac acccaacact
     6241 gctttccagg caggcgtcac cgggagtacc ggtccgttaa agcctcccgc cagcaggtta
     6301 cgcatcatca ggtaacctgc gcgattgggt ttcatcgatg cgccaattac cgcaatcgat
     6361 tttggtcgca gtagtgcttc cagtcctcgc tgactcatac cggtctcccg cagaagtgac
     6421 cgaatgattt taaacgcttt ctaactgttc tgctgtgatg ctacccagat gttgcgtttt
     6481 tcctgccaga tagcgtgttt taaagcgggt aaaatgctcg cctaaccctg ccgccgcccc
     6541 ggtatcgccg accatatcta acagtgcgat ggctacctcg gcagtacaat attggccttc
     6601 agcctgggct tcacgcaggc gataggcaga aagccgggaa agatcgacgg aaatgacggg
     6661 aagattatcc agatacggac ttttacgaaa catcttgcga gcttccggcc aggtaccatc
     6721 gagcatgata aatagcggag gcttaccggc aggtggtgtg aagatcactt cccgttgctc
     6781 atcagcatac gaggcgggaa agaccaccat tggctgatag tccgggtttt gtaccagatc
     6841 cagcaaatct agcgagggtt cggtacgcga ccattgaaac gcaacggtat caggcaaaat
     6901 atcagcaatc agacgcccgg tattactggg cttcattggc tcggtgtcga acatcagcaa
     6961 acagaagcga ctttttgctt gtgctggggt aattgtcgaa cagagacata atttctctgg
     7021 caaaagacag cgttggcagc gacgaacgcg attaccgcgg gcaagaaaag gacgtgttgc
     7081 gcgcgcaata cgctcggcgc gtaactggag aacagcgttt tcggtcataa gagagcgtcg
     7141 aaaaaacgcc attgtcgcag aggagaaaac ggggcacaag atgcgccccg gtaagattaa
     7201 agagattcgt tcagccagct atcaaacggc gctttcggta ctgcgccatt aagcatgtcg
     7261 acaacctgac cgtttttgaa aatcatgatc gtcggtatac tacgaattcc aaagcgactg
     7321 ctcaattcac gttcagcttc ggtattcact ttcacaaagc gcactttacc gctacgctct
     7381 tgcgcgacat cttcaaaaat tggcgcgaaa ttacggcagg ggccgcacca cggtgcccag
     7441 aagtcgatca ccacaggtag atcatctttc agcaatttgt cgagcgtttc accggtcgca
     7501 ttaatcacct ctccgtcaaa caagtcgtga ccgcagcgtc cgcattttgc cgcatcttcg
     7561 atccgatcgt cgggaatgcg attgatggcc tgacaatggg tacaaacggt attcataact
     7621 aacctcggga tgagtaagga gacttatcgg caacgacgcc ggtatgtttc taatatgtta
     7681 catattatcg gggacattgt tccagacaac aatctgtttt attcaatagg tatgatagtc
     7741 gtaggctttg gtacgaaatc atggcgaacc gcgcgcactt cgggtaatct gcgcgcttcg
     7801 cgcagcgctg gtggagaaaa gcatgaacga tgaaatgaaa ggtaaaagcg gcaaggtcaa
     7861 agtgatgtat gtccgcagtg atgatgattc tgataaacgt acccacaacc cgcgtaccgg
     7921 gaaagggggc gggcgtccag gaaaatctcg tgctgacggt ggccgtcgcc ccgcccgcga
     7981 tgacaaacag agtcagcccc gtgaccgcaa gtgggaagag tcgccgtggc gcacagtttc
     8041 ccgcgcgccg ggtgatgaga cgccggaaaa ggccgatcac ggtggcatca gtggtaaaag
     8101 ttttattgat ccggaagttt tgcgtcgtca gcgtgcggaa gaaacccgcg tctacggaga
     8161 aaacgcctgt caggcactgt tccagagccg tccggaagcg attgttcgcg cctggtttat
     8221 ccagagcgta acgccacgtt ttaaagaagc cttgcgctgg atggcggcaa accgcaaagc
     8281 gtaccatgtg gtggatgaag cggaactgac aaaagcgtca ggcacggaac atcacggcgg
     8341 cgtttgcttc ctgatcaaaa agcgtaacgg tacaaccgtg cagcagtggg taagccaggc
     8401 tggcgcgcag gattgtgtac tggccctgga aaacgaatct aacccgcata acctgggcgg
     8461 catgatgcgt agctgtgcgc acttcggcgt gaaaggtgtt gtggtgcagg atgcagcact
     8521 gctggagtct ggggcggcta tccgtaccgc agaaggcggc gcagagcacg ttcagccgat
     8581 tactggcgac aacattgtta acgtgctgga tgatttccgt caggcgggtt acaccgtagt
     8641 gacaacttcc agcgagcagg gtaaaccgct gttcaaaacc agtctgccag cgaaaatggt
     8701 actggtgctg ggtcaggaat atgaagggtt accggatgcc gcacgcgatc cgaacgatct
     8761 gcgcgtgaag attgatggta ctggcaacgt tgccgggctg aatatctctg tcgcaaccgg
     8821 cgttcttctt ggcgaatggt ggcgtcagaa taaagcctga taaatcagcc gggtggcaac
     8881 tctgccatcc ggcattttcc cgcaaattta ctcactctct gccggtaata ctggcatcca
     8941 gtcaatcggc gtctcgccac gttgttccag ccactgattt gccagcacaa aatggttgca
     9001 gccaaagaat ccacgatgcg ccgaaagcgg cgacggatgc ggtgctttca gtacatgatg
     9061 gcgttgctta tctataatcg cccctttctt ttgcgcatgc gatccccaca acaaaaacac
     9121 cacgccttcg cgatgctggt taatcaggct gatgacttta tcagtaaacg tctcccagcc
     9181 gaggctagcg tgggaatgcg cctgacctgc gcgaaccgtc aacacagtat tgagtagcag
     9241 aacgccctga cgcgcccagc tttcaagata accatgatta gggcgggtga aaccgggaat
     9301 agtattttcc agctctttat acatattcag cagtgacggc ggtgtcgcaa tgccggggcg
     9361 aacggaaaat gccagaccat gcgcctgtcc cggtccgtga taaggatcct ggccgagaat
     9421 caccacttta acgtcaccca actctgtaaa gcggaacgcg ttaaagacat ccttttgtgg
     9481 cggatagata gtgacgccgg actgccgctc gctggcgacg gtctgtaggg tattaagaaa
     9541 atagggttgt tgcttctctt cagccagcac gtcatgccag gttaattcgt ttgccatctc
     9601 gctctcccgc gaatcttcaa tccgcctagc ttaactgctt ctttctacag aacaaaatca
     9661 tgctcatttt ttagacttaa acgagtgcaa aaaaatgtaa attggtaaaa tttcacacct
     9721 gcataagttg atgtaaaaca ataaaatcca tttgcgacca tacttgatgt gtggttttta
     9781 ttgatttaaa tcaaagattc aagggtgttt gaggagtata tatacactca agcaacaatg
     9841 gttttaccaa ttggccgcga caggctgaac aaatcaaata attttgccgg ggaggcatca
     9901 catgattaca ggtatccaga ttactaaagc cgctaacgac gatctgctga actctttctg
     9961 gctgctggac agcgaaaaag gcgaagcgcg ttgcatcgtt gcgaaagcag gttttgcaga
    10021 agacgaagtg gttgcagtaa gcaaactggg tgacattgag taccgtgaag ttccagtaga
    10081 agtgaaacca gaagttcgcg ttgaaggtgg tcaacacctg aacgtaaacg ttctgcgtcg
    10141 tgaaactctg gaagatgcag ttaagcatcc ggaaaaatat ccgcagctga ccatccgtgt
    10201 atccggttat gcagttcgct ttaactctct gactccggaa cagcagcgcg acgttatcgc
    10261 tcgtaccttt actgaaagcc tgtaaggctt aagtagcaag ttactaagcg gaagagggcg
    10321 acctcttccg cttttttcat taatagaaaa tgcgtaccgc gcaatagacc agcagcagcg
    10381 cgagcacgat atttaactgg cgaccatact ggcgaaacaa tcgctgaaac aggtgccccg
    10441 ccagcgccca gcacacattg ccaaacgtcc caatcatcgc cagcaaaacg ctgacgccaa
    10501 ttatccagct tagcgcctgc gtttgcggca ggacaaacgt cgacagtgct gtaatgccat
    10561 acaaaatgat tttgacgttc acaaactgca aagcaaagct ggcccaaaaa ctgattggtt
    10621 ttgcctgaag cccatcttcc tttgttggac tggtagcgat tttccacgcc agccagacaa
    10681 tatatgccgc ccccgcccaa ctcaacagat gcactgctgc cgggtcgata acagccagtg
    10741 aaaacgaaat tcccgcgcat agcaacatga cgattaaaaa tcccagactc atccctgcca
    10801 gcacgcgagt actctgacga aatccgtgcg ttgtagctga gctaagggcg agaatattgt
    10861 tcggtcctgg cgtcatggcg gtaatcaggg tgtaagtcca aaaagcactt aaaagggtcg
    10921 gtgtcacttg ttatctcctc tgttttggta gacagtaccc gacacggaac atttaaaaaa
    10981 atgaatgttt ttacattcta aattcgatat tttcgatagg tttggggtta tggatctgcg
    11041 ccgttttatt acacttaaaa ccgtggtgga agagggttcc tttttgcgag cttcgcaaaa
    11101 attgtgctgt acacaatcga cggtgacttt tcatattcag cagcttgagc aggagttctc
    11161 agtccagtta tttgagaaaa ttggtcgacg aatgtgcctt acccgcgaag gaaaaaagct
    11221 gctgccgcac atttatgaac tcaccagagt gatggatacc cttcgtgagg ctgccaaaaa
    11281 agagtcggat ccggacgggg aactacgcgt tgtttcaggc gaaacgttgc tctcttaccg
    11341 aatgccgcag gtgttgcagc gttttcggca acgcgcacca aaagtgcgtt tatcgttgca
    11401 gtctctgaac tgttacgtga tccgtgatgc gctactgaat gatgaggccg atgtcggggt
    11461 tttttatcgc gtagggaatg ataatgctct gaaccggcga gagttgggtg aacaatcgct
    11521 ggtgctggtg gcttcaccgc aaattgcaga tgtcgatttt actgagcagg gaagacataa
    11581 cgcctgtagt tttattatca atgaaccgca atgtgtcttc cgccagatat ttgagagcac
    11641 gctgcgccag cgacggatca cggtggaaaa caccattgag cttataagta tcgaaagcat
    11701 caagcgttgt gtcgcggcaa atatcggggt cagttacctg ccgcgcttta cagtggcaaa
    11761 tgaacttgcg agtggcgaat taatcgaatt gccttttggc gaacagtcgc agacgattac
    11821 ggcaatgtgc gctcaccatg ccggaaaagc ggttagcccg gcgatgcaca tttttattca
    11881 gtgtgttgaa gagtgttttt tgccgggata aaaataatgc cgggcttaaa cccggcattg
    11941 agattactct tctgtcgttt gcggtggcac gcccgttccg ctcggtttac ggcgcttacc
    12001 aatatttttg gtgtcgcgat ggcgtttttt cacccgcggc ttctctttct ctttagcttt
    12061 tttcttctcg gcgcgttttg ccagtacttt cttcgatggc ttgccggtct gcttctcgct
    12121 tggcgcacgc gttttcgggc gtaactcatc aattacacga gctttaattg gctcttcaat
    12181 atagcgacca actttgccca gcagcagatg gtcatgggct tctaccagcg aaattgcggt
    12241 gcctttacga ccggcgcgcg cggtacgtcc gatacggtgc aaataagtat cgccactgcg
    12301 cggcatatcg aagttaaaga cgtggctgac gtcaggaatg tcgataccgc gcgcggcaac
    12361 atcggttgca accagtacgt ttacgcgacc ttcggtcaaa cgcttgatcg cttcgttacg
    12421 cttgccctgt accatctcac cttcgagata gcagttgttg atgcccgctt cgcgcagcca
    12481 gtttgccagc tcatgcacac gctcacgctt acgcacaaac acaattgagc gggtcgcttc
    12541 cggctgtttt aacaggtgca ccagcaatgc ggttttatgt tccaggtcat cggcgcggta
    12601 ataccactga tgaatttttt tgcgctcacg ggtggacgga ttggcagaaa cctccaccgg
    12661 atcttccagc agacgctcgg caaagtcctg aatcgcatcg ccttccagcg ttgccgaaaa
    12721 gagcagggtc tgtttacgcc agcgcgtttc gccagcaata tgttcgatat cctgagcgaa
    12781 gcccatatcc agcatacggt ctgcttcgtc gaggatcagc gtttcaaccg cgcggcaatc
    12841 gaagttctct tcttttatgt attgcagcag acgtccggtc gtggcgacca caatgtcctg
    12901 gttttcgctg aacacttctg cgtggttcat ataggccacg ccgccggtga tggtggcaat
    12961 atccagatgc gtatgtttcg ccagttcgcg ggcatgatcg gccacctgca tcgccagctc
    13021 gcgagttggg gtaaggatca aaatacgcgg cggaccggat ttcttacgtg ggaaatcgag
    13081 caggtgctgc aacgctggca gcagatacgc cgccgtttta ccggtgcctg tcggcgcaga
    13141 accgagtaca tcacggccat cgagcgcagg cggaatggcg gcagcctgaa tggcggtcgg
    13201 gcgagtgaaa cctttatcct ggagggcttc cagcaggctt tcgtcgagtt caagttcgga
    13261 aaaagtcgtt acagtcatgt tctacctctg tgtggggcgc tgattataga cgttacggct
    13321 gcaatcttca tctgtttgta tggatatcgc ttctcgggta ttgttctcac ccggtgctat
    13381 cgccgttttt cctgcaaggt tttattttca tgtcacagtc tacatccgtg cttcgtcgta
    13441 atggatttac ttttaaacag ttttttgttg ctcacgatcg ttgtgcgatg aaagtgggaa
    13501 cggatggcat tttgctgggc gcatgggcac cggtggctgg ggtaaaacgc tgccttgata
    13561 tcggcgcggg tagcgggttg ctggcattaa tgctggcgca gcgaaccgat gacagcgtaa
    13621 tgattgatgc agttgaactg gaaagtgaag ctgccgcgca ggcgcaggaa aatatcaacc
    13681 agtccccgtg ggcagagcgg attaacgtcc atacggcgga tattcagcag tggatcacac
    13741 agcagacagt acgcttcgat ttaatcatca gtaacccacc ttactatcag cagggagtag
    13801 agtgcgcgac acctcaacgg gaacaggctc gctataccac tacgcttgat cacccatcgt
    13861 tgctgacctg tgcggcggag tgcattaccg aagagggatt tttctgcgtg gtgctgccag
    13921 agcagattgg taatggtttt actgaactgg cattaagtat gggctggcat ttacgtttgc
    13981 ggacggatgt ggcggaaaac gaagcgcgac tgccgcatcg ggtgctgctg gcattctccc
    14041 cgcaggcggg agaatgcttt agcgatcgct tagtcattcg tgggccagac cagaactatt
    14101 ccgaagcgta tacggcgctg acccaggctt tttatctgtt tatgtaatga ttgccggggg
    14161 aaaggatcga cggaccggaa tgggtgagca gttccggata atccagcgtg aaatgcaacc
    14221 cccgactctc cttgcgcatc atcgcacagc gaacaatcaa ctcggcaacc tgtaccagat
    14281 tacgcagctc cagcaaatta tttgagacgc ggaaatgggc gtaatattcg tctatttctt
    14341 gttggagcat ggttatccgc cgcagggcgc gttccaggcg cttcgttgtg cgcacaatgc
    14401 caacgtaatc ccacataaac agacgtagct cgtgccagtt atgttgaatc accacccgtt
    14461 cgtcagggtt ctcaacacgg ctttcatccc acggcggtaa cgtactgacg tcgtgggcat
    14521 aaggcatacg cctggtaata tcctccgccg ctgaccagcc gtaaaccaga cactccagta
    14581 atgaattcga ggccatgcgg ttagcgccgt gtaagccggt ataactcact tcgccaatgg
    14641 cgtacaaacc ttcgacgtcc gtacgcccat gatcatccac cattacacca ccgcaggtat
    14701 agtgtgcagc aggcacaatc ggcacagggc ctttcgtgag atcaatcccc agtcccaata
    14761 acttttcata aatcatcggg aaatgctgac gaataaaatc ggcgggctta tggctgatat
    14821 cgaggaacat acaatctgcg ccgaggcgtt tcatttcgtg atcaatagca cgggcgacaa
    14881 tatcgcgcgg agccagttcg ccgcgttcgt caaaatcagg catgaaacgc gtgccatccg
    14941 gtcgcttgag ataagcgcct tcgccgcgca gtgcttccgt taacagaaaa ttgcgtgcct
    15001 gcggatgata cagcgcggta ggatggaact gattaaattc gagattggcg acccggcagc
    15061 ccgcgcgcca cgccatagca ataccatcgc cagaagaaat atccggattg gtagtgtact
    15121 ggtaaacttt tgacgcaccg ccggttgcca gtaccactgc ttttgcgtgg caggtttcca
    15181 ccgtttcttt atttcggttc catacccacg cgccaacaac ccgtcgcgtg cccggcaggc
    15241 caattttgtc agaaacaatc agatcaaccg cgttgctgcg ctccaacacg cgaatattcg
    15301 gatggttctg cgccttgccc accagcgtgg tttctacttc tctaccggtg gcgtcggcgg
    15361 catgaagaat acgacggtga ctatgtccac cttcacgagt cagatggtag ctttcttcgc
    15421 cattcggctg aacgtgggta tcaaacagca ccccctggtc gattagccat tgcacacagg
    15481 atcgtgcatt gctggcgaca aattcaactg catggcgatc gcaaatacca gccccggcaa
    15541 tcaatgtgtc ttccacatgc gagtcaatgc tgtcagtctc atcaaacacg gcggctatac
    15601 cgccctgggc ataaaatgtt gaaccttccg ttaccgggcc tttacttaga acgatgacct
    15661 gatgctggtc agccaggcgt agcgccagtg aaagtccagc tgcgccgcta ccgataatca
    15721 acacgtcaca tgaatgttca gggagagtat tcattttctt tgtttaattt actaaacatg
    15781 gtttggtcag catagcatca tgttgtgcga ataaacacct gctattttaa tatttgttac
    15841 agttgctaaa cacgctgacg cagggcggcg agaaaaagag aagttactgg ctggtggagg
    15901 attaggtggt gaaataaaaa ggccgttggg ttactcttca ggcagttaaa tgggcatttc
    15961 tacacagata atgcgatgtt cagattctgt agacttataa tgatagataa tgatccgtct
    16021 acagcatgac aaacaaaaac agatgcgtta cggaacttta caaaaacgag acactctaac
    16081 cctttgcttg ctcaaattgc agctaatgga gtggcgtttc gatagcgcgt ggaaatttgg
    16141 tttggggaga ctttacctcg gatgagcgag cagttaacgg accaggtcct ggttgaacgg
    16201 gtccagaagg gagatcagaa agcctttaac ttactggtag tgcgctatca gcataaagtg
    16261 gcgagtctgg tttcccgcta tgtgccgtcg ggtgatgttc ccgatgtggt acaagaagct
    16321 tttattaaag cctatcgtgc gctggattcg ttccggggag atagcgcttt ttatacatgg
    16381 ctgtatcgga ttgctgtaaa tacagcgaaa aattacctgg ttgctcaggg gcgtcgtcca
    16441 ccttccagtg atgtggatgc cattgaagct gaaaacttcg aaagtggcgg cgcgttgaaa
    16501 gaaatttcga accctgagaa cttaatgttg tcagaagaac tgagacagat agttttccga
    16561 actattgagt ccctcccgga agatttacgc atggcaataa ccttgcggga gctggatggc
    16621 ctgagctatg aagagatagc cgctatcatg gattgtccgg taggtacggt gcgttcacgt
    16681 atcttccgag cgagggaagc tattgataac aaagttcaac cgcttatcag gcgttgacga
    16741 tagcgggata ctggataagg gtattaggca tgcagaaaga acaactttcc gctttaatgg
    16801 atggcgaaac gctggatagt gagctgctta acgaactggc tcataaccca gaaatgcaga
    16861 aaacctggga aagctatcac ttaatccgtg actcaatgcg gggtgatact cccgaggtgc
    16921 tccatttcga tatctcttca cgagtgatgg ccgccattga agaagagcca gtacgtcaac
    16981 cggcgacatt gatcccggaa gcccagcctg cgccgcatca atggcagaaa atgccattct
    17041 ggcagaaagt acgtccgtgg gcggcacagc ttacccaaat gggcgtagcc gcatgcgtat
    17101 cgcttgcagt tatcgttggc gtccagcact ataatggaca atctgaaacg tcccagcagc
    17161 ccgaaacgcc ggtatttaat acactgccga tgatgggtaa agccagcccg gtaagcctgg
    17221 gagtaccttc tgaagcgacc gcaaacaatg gtcaacagca gcaggtacag gagcagcgtc
    17281 gtcgcattaa tgcaatgttg caggattacg aactgcaacg ccgactccac tctgaacagc
    17341 ttcagtttga gcaggcgcaa acccagcaag ccgctgtaca ggtgccagga attcaaactt
    17401 taggaacgca atcgcagtaa tgaagcaact ttggtttgcc atgtcattag tgacaggtag
    17461 cctgttattc tctgctaacg cctcggccac tcccgcgtcc ggggcgttat tacagcagat
    17521 gaacctggcc agtcagtcac tgaattacga gctgtcattc atcagcatca ataaacaggg
    17581 tgttgagtct ctgcgttatc gacatgcacg cctcgataac cgtcctcttg cacaattgtt
    17641 gcaaatggat ggcccgcgcc gggaagtggt acagcgcggc aatgagatca gctattttga
    17701 accgggactt gaaccgttca cgcttaatgg cgattacatt gttgattctc tgccatcgct
    17761 catctatacc gatttcaaac gcctttctcc ttactacgac tttatctccg tcgggcgcac
    17821 gcgtattgct gatcgtcttt gcgaagttat tcgcgtggtt gcccgagatg gtacacgcta
    17881 cagctacatc gtgtggatgg acaccgaatc gaaattaccg atgagggttg atctccttga
    17941 tcgcgatggt gaaacgctgg aacaatttcg cgtgattgct tttaatgtca atcaggatat
    18001 cagcagcagt atgcagacgc tggcgaaggc aaatttgccg ccgttgcttt ctgttcctgt
    18061 aggtgaaaaa gctaaattca gctggacgcc aacctggttg ccacagggtt ttagcgaagt
    18121 ttccagtagt cgacgtccgc taccgacgat ggacaacatg cctattgaat cacgtctcta
    18181 ttccgacgga ttattcagct tctcggtaaa cgttaaccgc gctacgccat cgagcaccga
    18241 tcagatgttg cgcaccggac gcagaaccgt cagtacaagc gtacgtgata acgccgaaat
    18301 caccattgtc ggtgaactgc cgccgcaaac ggcgaaacgc attgccgaga atattaagtt
    18361 cggggcagcg caatgatcaa agagtgggct accgtcgtct cctgggaaaa cgggcaggcg
    18421 ctggttagtt gtgatgttaa agcctcatgc agcagctgcg cttcgcgcgc cggttgcggt
    18481 agccgcgtgt tgaataaact tggcccgcaa accacgcata ccattgtcgt accctgtgaa
    18541 gaaccgttag tgccggggca aaaagtagaa ttaggaatcg ccgaaggcag cctgcttagc
    18601 tccgcattac tggtttatat gtcgccgttg gtgggactat tcctcatcgc ttcactattt
    18661 cagctactct ttgcttcaga tattgcagca ttatgcggtg cgattctcgg tggcgttggt
    18721 ggattcctga ttgcacgtgg ctgctctcga aagtttgctg cccggtctga atggcaaccg
    18781 atcatcttaa gcgtggcatt gccgcctggc cttgtgcgat ttgaaacatc ttcggaagac
    18841 gcgagccagt gatttcactg gctttgttgc attttgcata acaaatgcga ggacgtttcc
    18901 agataccaca atccatacgg tatgaacatt tcctcgcctc aatgttgtag tgtagaatgc
    18961 ggcgtttcta ttaatacaga cgttaagctc agaacagcga cttctaaaag cctggttaac
    19021 cgggcattaa ggcacaataa tcatacttta tgaagaatat acgtaacttt tcgatcatag
    19081 ctcacattga ccacggtaaa tcgacgctgt ctgaccgtat tatccagatc tgcggtggcc
    19141 tgtctgaccg tgaaatggag gcgcaggttc tcgattccat ggatcttgag cgtgagcgtg
    19201 gcattaccat caaagcgcaa agcgtgacgc tggactacaa agcgtctgac ggcgaaacct
    19261 atcagcttaa ctttatcgac accccgggcc acgtagactt ctcctatgaa gtttcccgtt
    19321 cgctggctgc ctgtgaaggt gcattgctgg tggtcgacgc cgggcagggc gtagaagcgc
    19381 aaaccctggc aaactgctac accgccatgg aaatggatct cgaagtggtg ccggtactga
    19441 acaagattga cctgccggca gccgatcctg aacgcgtggc ggaagaaatt gaagatatcg
    19501 tcggcatcga tgccaccgac gcggtgcgct gttcagcgaa aaccggcgtt ggcgtgcagg
    19561 acgttctcga acgtctggtg cgcgacattc cgccgccgga aggcgatccg gaaggcccgt
    19621 tgcaggcact cattatcgac tcctggttcg acaactacct gggcgttgtt tcacttatcc
    19681 gtattaaaaa cggcaccctg cgtaagggcg acaaagtgaa agtcatgagt accgggcaga
    19741 cctataacgc cgaccgtctg ggcatcttca cgccgaagca ggttgaccgt actgaactga
    19801 aatgcggcga ggtaggctgg ctggtatgtg cgattaaaga tatccacggc gctccagtag
    19861 gcgataccct aacgttggcg cgtaatccgg cagaaaaggc gctgcctggc tttaagaaag
    19921 tcaaaccgca ggtatacgcc ggtctgttcc cggtaagttc cgacgactat gaagccttcc
    19981 gtgacgcgct gggcaaactc agcctgaacg atgcttcact gttctatgag ccggaaagct
    20041 ccagcgcgct gggctttggt ttccgctgcg gcttcctcgg cctgctgcac atggagatca
    20101 tccaggaacg tctggaacgt gaatacgatc tggatctgat caccactgcg ccgaccgtag
    20161 tgtatgaagt tgaaaccacg tcaagagaag ttatctacgt cgacagccca tccaagctgc
    20221 ctgcggtaaa taacatttac gaactgcgcg agccgattgc agagtgtcac atgctgctgc
    20281 cgcaggcata tctcggcaac gttattacgt tgtgcgtaga aaaacgcggc gtgcagacca
    20341 atatggttta ccacggtaat caggtggcgc tgacgtacga gatcccgatg gcggaagtgg
    20401 tgctcgattt cttcgatcgc ctgaaatcta cctcgcgtgg ttatgcgtct ctggattaca
    20461 acttcaaacg cttccaggcg tccgacatgg ttcgtgtaga cgtattaatc aacggtgaac
    20521 gtgttgatgc gctggcgttg atcacccacc gtgataattc gcaaaaccgc ggtcgcgagc
    20581 tggtggagaa gatgaaagat ctgatcccgc gccagcagtt tgatatcgcc attcaggcag
    20641 cgattggtac gcacatcatt gcgcgctcca ccgtgaaaca gctgcgtaaa aacgtactgg
    20701 ctaaatgtta tggcggcgat atcagccgta agaaaaagct gctgcagaag cagaaagaag
    20761 gtaagaaacg catgaagcag atcggtaacg tcgagctgcc gcaggaagcg ttcctcgcca
    20821 ttctgcacgt cggcaaagac aacaaataac ccttaggagt tggcatggcg aatatgtttg
    20881 ccctgattct ggtgattgcc acactagtga cgggcatttt atggtgcgtg gataaattct
    20941 ttttcgcacc taaacggcgg gaacgtcagg cagcggcgca ggcggctgcc ggtgactcac
    21001 tggataaagc aacactgaaa aaggttgcgc cgaagcctgg ctggctggaa accggtgctt
    21061 ctgtttttcc ggtgctggct atcgtattga ttgtgcgttc gtttatttat gaaccgttcc
    21121 agatcccgtc aggttcgatg atgccgactc tgttaatcgg tgattttatt ctggtagaga
    21181 agtttgctta tggcattaaa gatcctatct accagaaaac gctgatcgaa accggtcatc
    21241 cgaaacgcgg cgatatcgtg gtctttaaat atccggaaga tccaaagctt gattacatca
    21301 agcgcgcggt gggtttaccg ggcgataaag tcacttatga tccgatctcg aaagagctga
    21361 cgattcaacc gggatgcagt tccggccagg catgtgaaaa cgcgctgccg gtcacctact
    21421 ccaacgtgga accgagcgat ttcgttcaga ccttctcacg ccgtaatggt ggggaggcga
    21481 ccagcggatt ctttgaagtg ccgaaaaacg aaaccaaaga aaatggaatt cgtctttccg
    21541 agcgtaaaga gacactgggt gatgtgacgc atcgtattct gacagtgccg attgcgcagg
    21601 accaggtggg gatgtattac cagcagccag ggcaacaact ggcaacctgg attgttccgc
    21661 cgggacaata cttcatgatg ggcgacaacc gcgacaacag cgcggacagc cgttactggg
    21721 gctttgtgcc tgaagcgaat ctggtcggtc gggcaacggc tatctggatg agtttcgata
    21781 agcaagaagg cgaatggccg acaggtgtgc gcttaagtcg cattggcggc atccattaat
    21841 agcccatctt cgttcacgtt gtcgccgtta tggcgacaac gtgaattatt tatgagataa
    21901 atctcccgtg gctaacgaca tcccccgtcg ttgtgtatag aatattcccc cgaagtttaa
    21961 ggttggcacc tccaggttgc cacggcacac gaaacagcgt tggtccccat ataccggtaa
    22021 actgaaactg cagcgaagca gttagcagaa ccatgtatat caggtctgtt tcgtgtgctg
    22081 aattgttgac gcatttattt attggtatcg catgaacccc atcgtaatta atcggcttca
    22141 acggaagctg ggctacactt ttaatcatca ggaactgttg cagcaggcat taacccatcg
    22201 tagtgccagc agcaaacata acgagcgttt agaattttta ggcgactcta ttctgagcta
    22261 cgttatcgcc aatgcgcttt atcaccgttt ccctcgtgtg gatgaaggcg atatgagccg
    22321 gatgcgcgcc acgctggtcc gtggcaatac gctggcggaa ctggcgcgcg aatttgagtt
    22381 aggcgagtgc ttacgtttag ggccaggtga acttaaaagc ggtggatttc gtcgtgagtc
    22441 aattctcgcc gacaccgtcg aagcattaat tggtggcgta ttcctcgaca gtgatattca
    22501 aaccgtcgag aaattaatcc tcaactggta tcaaacccgt ctggacgaaa ttagcccagg
    22561 cgataaacaa aaagatccga aaacgcgctt gcaagaatat ttgcagggtc gccatctgcc
    22621 gctgccgact tatctggtag tccaggtacg tggcgaagcg cacgatcagg aatttactat
    22681 ccactgccag gtcagcggcc tgagtgaacc ggtggttggc acaggttcaa gccgtcgtaa
    22741 ggctgagcag gctgccgccg aacaggcgtt gaaaaaactg gagctggaat gagcatcgat
    22801 aaaagttact gcggatttat tgctatcgtc ggacgtccga acgttggcaa atccacatta
    22861 ttgaacaaac tgctggggca gaagatctcc atcacctccc gcaaggcgca aacaactcgt
    22921 caccgcattg tggggatcca tactgaaggc gcgtatcagg cgatctacgt tgatacccct
    22981 ggcctgcata tggaagaaaa acgcgccatt aaccgcctga tgaacaaagc ggcgagcagc
    23041 tctatcggcg acgttgagct ggtgattttt gtcgtagaag gcacccgctg gacgccggac
    23101 gatgaaatgg tgctcaacaa actgcgcgat ggcaaagcgc cggtaatcct cgcggtgaac
    23161 aaagtggata acgtgcagga aaaagccgat ctgctgccac acttacagtt cctggcaagc
    23221 cagatgaact tcctcgatat cgtgccgatc tctgccgaaa ccgggttgaa tgttgatact
    23281 attgcggcaa ttgtgcgtaa gtatctgcct gaagcgactc atcacttccc ggaagattac
    23341 atcaccgatc gctcacagcg ttttatggcg tctgaaatca tccgcgaaaa actgatgcgt
    23401 ttcctcggcg ctgaactgcc gtactccgtg accgtggaga tcgaacgttt cgtctctaac
    23461 gaacgcggcg gttatgacat caacggtttg attctcgttg agcgtgaagg gcagaagaag
    23521 atggttattg gcaacaaagg ggccaagatc aaaaccatcg ggattgaagc gcgtaaagac
    23581 atgcaggaaa tgttcgaagc gcctgttcac cttgagctgt gggtaaaagt gaaatccggt
    23641 tgggccgacg acgaacgcgc actgcgcagt ctcggttacg ttgacgatct ttaagagtaa
    23701 ctccgatgga aggctggcag cgcgcatttg tcctgcatag tcgcccgtgg agcgaaacca
    23761 gcttgatgct ggacgtcttc acggaggaat cgggtcgcgt gcgtctggtt gccaaaggcg
    23821 cacgctctaa acgctctact ctgaaaggtg cattacagcc tttcacccct ctcttgctac
    23881 gtttcggcgg gcgtggcgaa gtaaaaacgc tgcgcagtgc tgaagccgtc tcgctggcgc
    23941 tgccattaag cggtatcacg ctttacagcg gtctgtacat caacgaactt ctctcccgcg
    24001 tactggaata cgagacgcgc ttctctgaac tctttttcga ttacttgcac tgcattcagt
    24061 cacttgcagg tgccactggt acgccagaac ccgcgctgcg ccgctttgaa ctggcactgc
    24121 tcgggcatct gggctatggc gtcaatttta cccattgtgc gggtagcggc gagccggtag
    24181 atgacaccat gacgtatcgt tatcgcgaag aaaaagggtt tatcgcaagc gtcgttatcg
    24241 acaataaaac gttcaccgga aggcagttaa aagcgttaaa cgcgcgggaa tttcctgacg
    24301 cagacacact gcgcgccgcg aaacgcttta cccgcatggc gcttaagccg tatcttggcg
    24361 gtaaaccatt aaagagcagg gaactgttcc ggcagtttat gcctaagcga acggtgaaaa
    24421 cacattatga atgatgagga ttgtcatggc tgaattactg ttaggcgtca acattgacca
    24481 tattgcaacg ctgcgtaacg cacgcggtac tgcttacccg gatccggtgc aggcggcgtt
    24541 tattgccgag caggcgggag cggacggcat taccgtgcat ttacgtgaag atcgccgcca
    24601 cattaccgac cgcgatgtgc gcatcctgcg tcagacgctg gatacccgca tgaatctgga
    24661 gatggcggtg accgaagaga tgctggcgat cgccgttgag acgaagccac atttttgctg
    24721 tctggtaccg gaaaagcgtc aggaagtaac aaccgaaggc ggcctggacg tcgcaggaca
    24781 gcgtgaaaaa atgcgcgatg cctgcaaaca tctggcggag gccgggatcc aggtttctct
    24841 gtttatcgac gccgatgaag agcagatcaa agctgcggca gaggttggcg caccgtttat
    24901 cgagatccac accggttgct atgctgatgc caaaactgac gccgaacagg cgcaagagct
    24961 ggcgcgtatc gccaaagccg cgacctttgc cgctagtctc ggtctgaaag ttaacgctgg
    25021 tcacggtctg acctatcaca acgtgaaagc cattgccgcc atccctgaga tgcatgaact
    25081 gaatatcggt catgccatta ttggtcgtgc agtgatgacc ggactgaaag atgcggtggc
    25141 agaaatgaag cgtttgatgc tggaagcgcg tggctaatgg caatattagg tttaggtacg
    25201 gatattgtgg agatcgctcg cattgaatcg gtgatcgccc gatccggtga gcgcctggca
    25261 cgccgcgtat taagcgataa cgaatgggca atctggaaaa cgcaccacca gccggtgcgt
    25321 tttctggcga agcgttttgc tgtgaaagaa gcggcggcaa aagcgtttgg caccgggatc
    25381 cgcaatggtc tggcgtttaa tcaatttgaa gtattcaatg atgagctcgg caaaccacgg
    25441 ctacggctat ggggtgaggc attaaaactg gcggaaaagc tcggcgttgt aaatatgcat
    25501 gtaacgctgg cagatgaacg ccactatgct tgtgccacgg taattattga aagttaaaaa
    25561 aataccgttc tctttataaa gtaaaacccc cgaactggta aggaacgggg gttttcactt
    25621 tacaacttta attttgtgca gcacacgatt ccaacggaaa taattatgga tcaatttagt
    25681 tgacctgtac aagcaacttg caatctctga cataaaaaac gcgagccttt acgaagaaat
    25741 cgacattgat gaaaagatta acgtgaccgc tttttgataa gtacattaaa atcggtttcg
    25801 ttattggcaa ttttgctgtg ctttacacca tgccactgaa ttcccccatt gaaacgagtg
    25861 gtgtcgtcaa agctctggtg tggagtgcag cactcgattc caataactcg cacgttcagt
    25921 tttggggaga tgtaagggct aatctgaacg gctgcattcc ttgtttaagg aaaaacgaat
    25981 gactgattgc cgatacctta ttaaacgggt catcaaaatc atcattgctg ttttacagct
    26041 gctccttttg ttcttataac acaaggaaac gtacttaagg tgcgtccggt gaaccagtcg
    26101 gacgcgcctt taataactat aaataagtgt ctgggcagat actatataaa tttacttagt
    26161 gaatgattat gctaatttca tcatttaaat aaatataata gcgttaaggt ttctctataa
    26221 gataattaac actctacttc cagagcagaa tattaaattt tatccgcgtg gtgcatcagc
    26281 acaaatttat cccacaactg ttcttccgtc tcgacatgtt gcggatcttt cacaatagta
    26341 ttggggatcg gacacacctt ctggcaggtt ggtgtctcgt agtgccctac gcattcggta
    26401 cacttatcgc tgttaatctc gtagatatga tcgcccattg aaatcgcctc attcgggcat
    26461 tcgggttcac acatatcaca attgatgcat tttttagtga ttaacagcgc cataaggaaa
    26521 ctctcaaaac aacacaaacc gggcgggcat tatacgcgca ttctttactc agaccagttt
    26581 tttcaccagc gcttcactat gacgaatacg ttctggtgcc agttccagat cctgctgaat
    26641 cagcgcaatg aacagcaaat ccgttaacat tccctgcgcg tggcaagcag agattgaagc
    26701 actgtttgtc gcttgttctt cggcaatggt atacaggcaa tgagaagcac gctgttgcag
    26761 ggcattggga gtaaagccgg taatcgccag cacttttccg cccactcgca gcatctcatc
    26821 tgccgccagg tttaactcgc gccgtacacc ggtgtaggaa atggctaata acagatcgtc
    26881 aggggacgac gcctgtactg tagcgagtag cgcatgcata tcgcgcactg cggcagcatt
    26941 gaagccaatc ttcatcagct tccaggcaaa gttttgcgcc accagacccg aagcgccaat
    27001 accggtcaga attatccgcc gcgcagagcg caacattgcc acgcactcat gcagcttctc
    27061 ttcactatta acgtttagcg ttgcgtacat ggcggcagta ttttctttaa tcaatttttc
    27121 gccgaccagc cgtaacggat catcaccgcg gatttggtta tgaatgggca cggagggaga
    27181 ttccggctgg cttgccagcg cttcactcaa cgccaactta agtgccggaa aacctttata
    27241 gccgagtttt tgcgcgaact tcacgacgct ggactgactg actccggctt cgttggccag
    27301 ttgctgagag cttaaatggc gcgccgtatc aggttgtagc agcagataat ccgccagttt
    27361 tttatcactc tgggcaagcc cctggtaacg ctgacggata cgaagtaagc cgttcatatc
    27421 tttcctcgcg atgaaatagt ggcgacaaca ggcaatatga gacaaacgcg agtgaatttt
    27481 atattccatt gccgctaatt gccatgaatt aaaaattcca gttagccatg atgcggtcga
    27541 ttgttgccgg aaaagtgatg atctatctgt taggctatgt agtagcgaaa attaatcagg
    27601 atgtttcagt ccagaggagt atggtttggc aactcacgag cgtcgtgtgg tgttttttga
    27661 cttagatgga acattgcatc agcaggatat gttcggcagt tttttgcgtt atttactgcg
    27721 tcgccaaccg ctgaatgcgt tgcttgtcct gccgttgttg ccgatcatag ccattgcgtt
    27781 attgataaaa ggccgtgcgg cacgctggcc gatgagtctg cttctgtggg gatgcacttt
    27841 tggtcacaat gaagcgcgtt tgcaggcgtt gcaggccgat ttcgtacgct ggtttcgtga
    27901 caatgttacc gcctttccgc tggttcagga gcgattaacc acctacctgt taagttccga
    27961 tgctgatatc tggttgatta ccggctctcc gcagccgctg gttgaagcgg tttatttcga
    28021 tacgccctgg ctgccgcggg ttaatcttat cgccagtcag attcagcgtg gctatggtgg
    28081 ttgggtattg acgatgcgtt gcctcgggca tgagaaggtc gcgcaactgg agcgcaaaat
    28141 cggcacgccg ctgcggctgt acagtggcta tagcgacagt aatcaggaca acccgctgct
    28201 ttatttctgt cagcatcgtt ggcgagtaac cccgcgcggt gaactccagc aactggaata
    28261 gagtaaagca tagcgtccgt gtataatgcg ccgcgctttt ataaccggag ttttcttttt
    28321 gtctgaagtc gaatttagcc acgaatactg gatgcgtcat gcaatgacgc tggcgaagcg
    28381 tgcctgggat gagcgggaag taccggtcgg cgcggtatta gtgcataaca atcgtgttat
    28441 tggcgaaggc tggaaccgtc cgattggtcg acatgatccc accgcacatg cagaaatcat
    28501 ggccctacgg cagggcggtc tggtgatgca aaattatcgt ctgatcgacg ccacgttgta
    28561 tgtcacgctt gaaccctgtg taatgtgtgc cggagcgatg atccacagtc gcattggtcg
    28621 cgtggtcttt ggtgcgcgtg acgcgaaaac tggcgctgcg ggatctttaa tggatgtgct
    28681 acatcatccg ggtatgaatc accgggtgga aattacggaa ggaatactgg cggatgagtg
    28741 cgcggcgttg ctcagtgact tctttcgcat gcgccgccag gaaattaaag cgcagaaaaa
    28801 agcgcaatcc tcgacagatt aattttgttt ctcttcactc ccttttctgg aaaatagcag
    28861 agagggagag tgggtcaaat agtttgatga cgactgggaa agaaacgaga gaaaaggaaa
    28921 tttctctttg cccaactccg taggcgatac cgccggataa tcctgcgcca gttgcatcgc
    28981 cgcttctgta gcctgcttct ctttctcttg cagataaccc accaggctaa tctgatactt
    29041 acgaatattt tcgacataag cgtaggcttc atgcccacga gcgtagccgt aagtcagctt
    29101 gctgtaatag ggtttctggc taagtaaagg cagacgctgt tttacgtcag cccaactgtc
    29161 aggattccct ttggtttttg ccgtcagagc gcgggcatcc agcatatgcg catagcccat
    29221 attgtacgcg gcgagggcaa accaaatccg ttcgttctcc ggcacacttt ccggcacttt
    29281 actcatcata tcctgcaaat aacgcacgcc gccgctgatg ctctgttcgg catcggtacg
    29341 atccgtaatg ccgaggcttt gcgcggtatt tttggttagc atcatcatgc cgcgcacacc
    29401 cgtcggtgaa gtggcctgcg catcccagtg cgattcctga taagcaatag cggccagcaa
    29461 acgccagtca atttcttcgg cgtatttctc aaacaggggc tttaactgcg gcagtaccgc
    29521 atcgacggcg cgtaaaaatg tgcgcgtatc gacgtaatca aaatcatcgc catgccccag
    29581 gtatttctct tcaatgcgtg ccagcgtacc gtcttcattc atctcattga agaaatcgag
    29641 cagagcggcg gaaagggtat tatcgccatc taacgggcta aaccaggtca ctggttgttc
    29701 atcggtgata tcgagcgcta cggcgagttc cgggtgaacg cgctgaaaca ggctgatggc
    29761 gacagaatca gcaatggtgt aatcgagttt tccttcgatg acatcttcca ttaattccgc
    29821 agagcctttt ttgtcgtcta ccttccagct taattccggg aattttgtgt ctttcagggt
    29881 ctggagatcg ttaaccacca cgtgacccgg tgcaacggtg agttgctctg ccgtcaggtt
    29941 gcccagcgta cgtgggcgat actgacccac tttataaacc agttgttgtg acacggaata
    30001 ataggtagga ccaggctgat aattttttac ccgctcactg ttatagacca gtcctgccgc
    30061 cagcaggtcg gcgttaccat tatcgaggtc gtcaaacagc tggctgatat tctgccgcac
    30121 ggtcactttc agttttacac cgaggtaatc ggcaaactgt ttcgccagtt cgtaatccag
    30181 gccaaaaggt ttcccgttga tttcgttata cgtcagggga gtatgaatgg tgctcacacg
    30241 caactctccc cgcgcttgaa tggcggcgat acggttgtcg gctttaccaa accagggaat
    30301 ggatggccag agagcgaccg cgagcagcag tgccagaatg ccgatgaaca gataattaat
    30361 ctttaatttt ttcaattagt taattctctg tgtcgtgcgc gtcccagctt gaaaaaacgt
    30421 aataatagtg aaaggtttac tcataaatga gcggcatttt gcgtaaacct gcgccagttg
    30481 gcaacttatt acagccattg gcggcacgcg ttgctaattc acgatggtga ttttatttcc
    30541 acgcaaacgg tttcgtcagc gcatcagatt ctttataatg acgcccgttt cccccccctt
    30601 gggtacaccg aaagcttaga agacgagaga cttatgatgg aaattctgcg tggttcgcct
    30661 gcattgtcgg cattccgaat caacaaactg ctggcacgtt ttcaggctgc caggctcccg
    30721 gttcacaata tttacgccga gtatgtccat tttgctgacc tcaatgcgcc gttaaacgat
    30781 gatgagcacg cacaacttga acgcctgctg aaatatggcc cggcactcgc cagccacgcc
    30841 ccgcaaggca aactcctgct ggtgaccccg cgtcctggca ccatctctcc ctggtcttcg
    30901 aaagcgaccg atatcgccca taattgcggt ctacaacagg taaaccgcct tgagcgcggc
    30961 gtggcttact atatagaagc cggtacgctg actaatgaac aatggcagca ggtgaccgct
    31021 gaactgcacg accgcatgat ggaaacggtc ttttttgctt tagatgatgc agagcagttg
    31081 tttgctcatc atcagccaac cccggtcacc agcattgatt tgctggggca gggccgtcag
    31141 gcgctaatcg acgctaacct gcgtcttggt ctggcgctgg cggaagatga gattgactat
    31201 ctgcaggatg cgttcacaaa gcttggtcgt aacccgaacg acatcgagct gtatatgttc
    31261 gcgcaggcga actccgagca ctgccgtcac aaaattttta acgccgactg gattatcgac
    31321 ggtgaacagc agccgaaatc gctgttcaag atgatcaaaa acaccttcga aaccacgccg
    31381 gatcacgttc tctctgctta taaagataac gccgccgtca tggaagggtc tgaagtgggc
    31441 cgctactttg ctgaccacga aacgggccgc tacgatttcc atcaggaacc ggcgcatatt
    31501 ctgatgaaag tcgaaactca caaccacccg acggcgattt ctccgtggcc gggcgcggcg
    31561 accggttccg gcggtgaaat ccgcgatgaa ggtgccaccg ggcgtggcgc aaagccgaaa
    31621 gccggtctgg tcggtttctc cgtatccaac ttgcgtattc cgggctttga acagccgtgg
    31681 gaagaagatt tcggtaagcc tgagcgcatt gtcaccgcgc tggacatcat gaccgaaggc
    31741 ccgctgggcg gcgcggcgtt taacaacgaa tttggtcgcc cggcactgaa cggctacttc
    31801 cgtacttatg aagaaaaagt gaacagccac aatggcgaag agctgcgcgg ttatcacaaa
    31861 ccgatcatgc tggcgggtgg gatcggcaac attcgcgccg atcacgtaca aaaaggcgag
    31921 atcaacgttg gtgcgaagct ggtcgttctc ggcggcccgg caatgaacat cggtcttggc
    31981 ggcggcgcgg cgtcttccat ggcatctggt cagtctgatg cggacctcga ctttgcttcc
    32041 gtacagcgcg acaacccgga gatggagcgt cgctgccagg aagtgatcga ccgttgctgg
    32101 cagcttggtg atgccaaccc aatcctgttt atccacgacg ttggcgcagg cggtctttct
    32161 aacgccatgc cggaactggt gagcgacggc gggcgcggcg gtaaattcga actgcgcgat
    32221 atcctgagcg acgaaccggg catgagcccg ctggaaatct ggtgtaacga atcccaggaa
    32281 cgctacgtgc tggcggttgc tgccgatcag ttaccgctgt ttgacgaact gtgtaagcgt
    32341 gagcgcgcgc catacgcggt gattggcgag gccaccgaag aattacatct ttctttgcac
    32401 gatcgtcatt ttgataatca gccgatcgat ctgccgctgg acgtactgct tggtaaaacg
    32461 ccgaagatga cccgcgaagt acaaacgctg aaagcgaagg gtgatgcgct ggttcgtgaa
    32521 gggattacca ttgctgacgc ggtgaaacgc gtgctgcacc tgccgaccgt ggcggagaaa
    32581 actttcctgg tgaccattgg tgaccgcagc gtaaccggca tggtagcgcg cgatcagatg
    32641 gtgggtccgt ggcaggtgcc ggtcgctaac tgcgcggtca ctaccgccag cctcgatagc
    32701 tactacggcg aagcgatggc gattggcgag cgtgcgccgg ttgcgctgct ggatttcgcc
    32761 gcctctgccc gtctggcggt cggtgaagcg ttaaccaata ttgccgcaac acagattggc
    32821 gatatcaaac gcattaaact ttccgccaac tggatggcgg cggcaggcca ccctggtgaa
    32881 gatgcgggcc tgtatgaagc cgttaaagct gtgggcgaag aactttgtcc ggcgctgggc
    32941 ctgacgatcc cggtgggtaa agactctatg tcgatgaaaa cccgctggca ggaaggtaac
    33001 gaagagcgcg aaatgacgtc gccgctgtcg ctggtgattt ctgcatttgc ccgtgtggaa
    33061 gatgtgcgtc acaccatcac gccgcagctt tctaccgaag ataacgcatt actgctgatt
    33121 gatctgggca aaggcaataa cgcgctgggc gcaacggcgc tggcgcaggt ttatcgtcag
    33181 cttggcgaca aaccggcaga tgtacgcgat gttgcgcaac tgaaaggctt ctatgacgcg
    33241 attcaggcgc tggttgcaca acgtaagctg ctggcatatc acgaccgctc tgatggcggc
    33301 ctgctggtaa cgctggcgga aatggccttt gctggtcatt gtggcattga cgcagatatc
    33361 gcctctctgg gtgacgatcg cctggcggcg ttgtttaacg aagaactggg tgcggtgatt
    33421 caggttcgtg ccgctgaccg tgaagcggtc gagtccgtac tggcgcagca tgggcttgcg
    33481 gattgcgtcc attatgtagg gcaggcggtt tccggtgacc attttgtgat tactgccaac
    33541 gggcagactg tatttagcga aagccgcacc acgttgcgtg tctggtgggc agaaactacc
    33601 tggcagatgc agcgtctgcg tgacaacccg gagtgtgctg accaggagca ccaggcgaaa
    33661 tcaaacgacg ccgatccggg cctgaatgtg aaactgtcgt tcgatatcaa cgaagatgtg
    33721 gcagcaccgt atattgccac tggcgcacgt ccgaaagttg ccgtactgcg tgagcagggc
    33781 gtgaactcgc atgttgaaat ggcggcagct ttccaccgtg caggcttcga tgctatcgac
    33841 gtgcatatga gcgacctgct ggctggacgc acgggcctgg aggatttcca cgccctggtc
    33901 gcgtgcggtg gtttctccta cggtgatgta ctgggtgccg gtgaaggttg ggcgaagtct
    33961 atcctgttca atgaccgtgt acgcgatgag tttgcaacct tcttccaccg tccgcaaacg
    34021 ctggcgctgg gggtatgtaa cggttgccag atgatgtcta atctgcgtga actgatccct
    34081 ggtagcgagt tgtggccacg ttttgtgcgt aacacctccg atcgctttga agcgcgtttc
    34141 agtctggtag aagtaaccca aagcccgtcg ctgctgttgc aggggatggt gggctcgcag
    34201 atgccgattg ctgtctctca cggtgaaggg cgcgtggaag tgcgtgatgc ggcgcatctg
    34261 gcggcactgg aaagcaaagg gctggtggca ctgcgctatg tcgataactt cggcaaagtc
    34321 actgaaacat acccggctaa cccgaacggt tctccgaatg gtattacggc ggtcacgact
    34381 gaaagcggtc gagtcaccat tatgatgccg cacccggaac gtgttttccg tactgtcagt
    34441 aactcctggc atccggaaaa ctggggcgag gatgggccgt ggatgcgtat tttccgcaat
    34501 gcacgtaagc agttggggta agccgtcaac ccattggttt tgcagccgga tgaggcatta
    34561 agcaccaact actattataa gctcccaact tcgggagctt ttttgtgtct gtaaatcacg
    34621 acaatgggtg gtttaccgtg tcgctttctg gcgacactta actaattgat tttaatggca
    34681 tctaataagt ttatcttaag ttgtctcttt ttagcgacac agtggctgat ttacagccaa
    34741 atagcgaaga agccataacc ccttcaaaac agcgtacaat cagtacgtta ccaaactatt
    34801 ttctttattg gcacagttac tgcataatag taaccagtgg ctcattcacc gacttatgtc
    34861 agccccttcg ggacgtgcta cataaaattc gaatgacgca caacaaggtg cctgccgtcc
    34921 aacttctgat atcagcgtag ctatatcaac cctcgggcga aacgtcgagt taggcaccgc
    34981 cttattccat aacaaagccg ggtaattccc ggctttgttg tatctgaact tcccctcggt
    35041 tagcatcagg ctattcgcgt ctgacgagag taacaccttg aaacgctggc ccgtttttcc
    35101 ccgctcatta cgacaactgg taatgctggc atttttgctg attctgctac ccctgttggt
    35161 gctggcatgg caagcctggc aaagcctgaa tgcgcttagc gatcaggcgg cgctggttaa
    35221 ccgcactacg cttattgatg cccggcgcag tgaagcgatg accaacgcgg cactggaaat
    35281 ggagcgcagc taccgtcagt attgcgtgct ggacgaccct acgcttgcga aggtttatca
    35341 aagccagcgc aagcgttata gcgaaatgct cgatgcccac gcaggcgtgc tgccggacga
    35401 taaactctac caggcattac gtcaggattt gaataatctg gctcaacttc agtgtaacaa
    35461 cagcggtccc gatgctgctg ccgccgcgcg tctggaagcc tttgccagtg ccaataccga
    35521 aatggtgcag gccacgcgca cagtggtgtt ctctcgtggg cagcaacttc agcgtgaaat
    35581 cgccgaacgt gggcaatatt ttggttggca atcgctggtg ctatttctgg tgagtctggt
    35641 gatggtgcta cttttcacga ggatgattat cgggccggtg aaaaatatcg agcgcatgat
    35701 caaccggctg ggggaagggc gttctctggg caatagcgtc tcgttcagtg gaccgagcga
    35761 gttacgctcg gttgggcaac gtattctttg gttaagtgag cgcctgtcat ggctggaatc
    35821 ccaacgccat caatttttaa gacatttatc tcatgaatta aaaaccccgc tggcgagtat
    35881 gcgcgagggc actgaattac tggctgacca ggttgtcggg ccgcttacgc ccgagcaaaa
    35941 agaggtggtg agcatccttg atagcagcag ccgcaatttg caaaaactga tcgaacaact
    36001 gcttgattac aaccgtaaac aagcggacag tgcggtggaa ctggagaatg ttgagttagc
    36061 accgctggtg gagacagtag tttctgctca tagcctgccc gcacgggcta aaatgatgca
    36121 taccgacgtt gatctcaaag caacagcttg cctggcggag ccaatgctgc tgatgagcgt
    36181 actggataat ctttactcca atgcggtgca ctacggggct gaatccggta acatttgcct
    36241 tcgcagcagt ttacatggtg cgcgggttta tattgatgtc atcaatacag gcacgcccat
    36301 tccgcaagag gaacgcgcca tgatcttcga accctttttt cagggaagcc accagcgaaa
    36361 aggggcggtg aagggcagcg gtctgggatt aagcattgcc agggattgta ttcgccgtat
    36421 gcaaggggaa ctgtatctgg tcgacgagag cgggcaagat gtttgtttcc gcattgaatt
    36481 accgtcgtcg aaaaacacga aataatgcta acagcctatc ccatcaggct attttatttg
    36541 ccagtttggc cccgggcagt gctcgaaatc ttcacgtacg acatgtacgc tccggtttct
    36601 ccgcgctgtc catgtccaaa ctgcctgcaa caattacgcc cactgggata ggctttaagt
    36661 ctggtgaata tgcgacacat ttttcaacga ttattgcccc gacggctgtg gctggcaggg
    36721 ctgccatgtc tggcattgct gggttgcgtg cagagtcaca ataagccagc cattgatacg
    36781 ccagcagaag aaaaaattcc ggtttatcaa ctggctgact atctttctac tgaatgtagc
    36841 gacatctggg cgctgcaagg taaatcaacc gaaaccaatc cgctttactg gctgcgggcg
    36901 atggattgtg ctgatcgttt aatgcctgcg cagtcgcgtc agcaagcccg ccaatatgac
    36961 gacggcagct ggcaaaatac ctttaaacaa gggattttgc tcgccgacgc caaaattacg
    37021 ccgtatgagc gccgccagct ggtcgcgcgc attgatgcgc taagtaccga gatcccggca
    37081 caggttcgcc ctctgtatca actctggcgc gacggtcagg cgctgcaact gcaactggcg
    37141 gaagagcgcc aacgctacag taaactccag cagtccagcg acagcgagct ggatactttg
    37201 cgccagcaac atcacgttct acaacagcaa ctggaactca ctacccgcaa gctggaaaac
    37261 ctgaccgata ttgaacgcca gctctcgacc cgcaaaccgg ctggaaattt ctcgccggat
    37321 acgccgcacg agagtgaaaa gcccgcgcca tccaccgatg aggtcactcc tgatgagcca
    37381 taaacctgcg catttattat tggtcgatga cgatccggga ttgctgaaac tgcttggcct
    37441 gcgcctgacc agcgaaggct acagcgtggt cacggcggaa agtggcgctg aaggattacg
    37501 ggtactgaat cgcgaaaaag tagatttagt catcagcgac ctgcggatgg atgaaatgga
    37561 cggtatgcag ctgtttgctg aaatccagaa agtgcagccg ggaatgccag taattattct
    37621 taccgcgcat ggttctattc ccgatgccgt tgctgcaaca cagcagggcg tgttcagttt
    37681 tctcaccaag cctgtcgata aagacgcgct atatcaggca attgacgatg cgctggaaca
    37741 atccgcgcca gccaccgacg aacgctggcg cgaggcgatt gtcacccgca gcccgctgat
    37801 gctgcgtttg ctggaacagg cgcggctggt ggcgcaatca gacgttagcg ttttgattaa
    37861 cggccagagc ggcaccggga aagagatttt cgcccaggct atccacaacg ccagcccgcg
    37921 caacagcaaa ccatttattg ctattaactg tggcgcattg cccgagcaat tgctggagtc
    37981 ggagctgttt ggtcatgcgc gtggtgcgtt tactggcgct gtcagcaatc gcgaaggttt
    38041 attccaggcg gcggaaggcg gtacgctatt tctcgatgag attggcgata tgcctgcacc
    38101 gttgcaggtc aaactgctgc gcgtgttgca ggagcgtaaa gtgcgcccgc tgggcagtaa
    38161 ccgcgatatt gatatcgacg tgcggattat ttccgccact caccgcgacc tgccaaaagc
    38221 gatggcgcgc ggggaattcc gtgaagatct ctattaccgc ctcaacgttg tcagcctgaa
    38281 aattccggct ctggcagagc gcacagaaga cattccgcta ctggcaaatc acctgttgcg
    38341 ccaggcggca gagcgacata aaccgtttgt ccgcgcgttc tccaccgatg caatgaaacg
    38401 cctgatgacc gctagctggc cgggtaatgt acgccagttg gtcaacgtga ttgaacagtg
    38461 cgtggcgctg acctcatctc cggtgattag tgatgcatta gtagagcagg cgctggaggg
    38521 tgaaaatacg gcgctgccaa cctttgttga ggcacgtaat cagtttgaac tcaactattt
    38581 gcgtaagctg ctgcaaatta ccaaaggcaa cgtcacccac gcggcgagaa tggcggggcg
    38641 caaccggaca gaattttata aactgctttc ccgacacgag ctggatgcaa acgatttcaa
    38701 ggaatgaatt ggcgttatgt gttacgttta gcagatcaaa agacaggcga ccttttcaag
    38761 gaatagcatg aaaaagattg atgcgattat taaacccttc aagctggacg atgttcgcga
    38821 agcactggct gaagtcggca ttaccggcat gacggtcact gaggtgaaag gttttggccg
    38881 ccaaaaaggc cataccgagc tgtaccgcgg cgcggagtat atggtggatt ttctgccgaa
    38941 ggtgaaaatt gagattgtcg taccggacga cattgttgat acctgtgtcg ataccattat
    39001 tcgcacggcg caaaccggca aaatcggtga cggtaaaatc ttcgtcttcg acgtggcacg
    39061 ggtcattcgc atccgtaccg gtgaagagga cgacgcggca atttaaaccg cgtcaagggt
    39121 tgccggatgt ttccatccgg caacatcaaa tcacagcacc ttatgcggac caaagcattc
    39181 gtaatgaatg ttttcctgtt tcacgcccag atccactaac tgtttcgcgg caaactgcat
    39241 gaagccaacc gggccgcaga gatagaactg cattgtcgga tcgctgaacg caccttccag
    39301 tttgctcaaa tccatcagac cttcgctatc aaactgacct ttagcgcgat cggcttcgct
    39361 tggctgacga taccaggtgt gcgcggtaaa gcgcggcagt gcttgcccca gttccttaac
    39421 ttcatcggca aaggcgtgaa catcgccatt ttctgccgca tggaaccagt tcacttgtgc
    39481 tgtgtggcca gcttttgcca gcgtgtcgag cattgccagc attggcgttt gaccgacacc
    39541 ggcagagatt aacgtcactg gtgtgtcatc tgcgacagcc ataaagaaat cacctgccgg
    39601 agcgaccagt ttcacgacat cgccaacatt ggcgtgattg tgcagccagt tggatacctg
    39661 cccaccctct tcgcgtttca ccgcaatacg atagcctttg ccatccggtt tgcgagtcaa
    39721 agagtactga cgaatttcct gatgcgggaa accttccggc ttcagccaga cgccgagata
    39781 ttgccccgga cggtattctg ccactgcgcc accgtcgacc ggctccagtt cgaagctggt
    39841 gataagcgcg ctgcgcggtg ttttagccac aatgcggaaa tcgcgagtac cttcccagcc
    39901 accggctttg ctggcgtttt cgttatagat ttccgcctcg cgattgataa atacattagc
    39961 cagtacgcca taggctttac cccacgcgtc cagcacttcc tggcccgggc tgaacatttc
    40021 gtccagcgtc gccaacaggt gttcaccgac aatgttgtac tgttccggtt tgatctggaa
    40081 actggtgtgc ttctgcgcga ttttttctac cgctggcagc agcgcaggca ggttttcaat
    40141 attactggcg taggcggcaa tagcgttaaa cagggcttca cgttgatcgc cattgcgctg
    40201 gttactcatg ttaaaaattt ctttgagttc tgggttatga gtaaacatac ggtcgtagaa
    40261 atgggcggtt aactttggcc ccgtttccac cagtaaaggg atggtggctt ttactgtagc
    40321 gatggtttga gcgtcaagca tatggtcttc ctttttttgc atcttaattg atgtatctca
    40381 aatgcatctt ataaaaaata gccctgcaat gtaaatggtt ctttggtgtt tttcagaaag
    40441 aatgtgatga agtgaaaaat ttgcatcaca aacctgaaaa gaaatccgtt tccggttgca
    40501 agctctttat tctccaaagc cttgcgcagc ctgaaggtaa tcgtttgcgt aaattccttt
    40561 gtcaagacct gttatcgcac aatgattcgg ttatactgtt cgccgttgtc caacaggacc
    40621 gcctataaag gccaaaaatt ttattgttag ctgagtcagg agatgcggat gttaaagcgt
    40681 gaaatgaaca ttgccgatta tgatgccgaa ctgtggcagg ctatggagca ggaaaaagta
    40741 cgtcaggaag agcacatcga actgatcgcc tccgaaaact acaccagccc tcgcgtaatg
    40801 caggcgcagg gttctcagct gaccaacaaa tatgctgaag gttatccggg caaacgctac
    40861 tacggcggtt gcgagtatgt tgatatcgtt gaacaactgg cgatcgatcg tgcgaaagaa
    40921 ctgttcggcg ctgactacgc taacgtccag ccgcactccg gctcccaggc taactttgcg
    40981 gtgtacactg cgttgctgga accaggcgat accgttctgg gtatgaacct ggcgcatggc
    41041 ggtcacctga ctcacggttc tccggttaac ttctccggta aactgtacaa catcgttcct
    41101 tacggtatcg atgctaccgg tcatatcgac tacgccgatc tggaaaaaca agccaaagaa
    41161 cacaaaccga aaatgattat cggtggcttc tctgcatatt ccggcgtggt ggactgggcg
    41221 aaaatgcgtg aaatcgctga cagcatcggt gcttacctgt tcgttgatat ggcgcacgtt
    41281 gcgggcctgg ttgctgctgg cgtctacccg aacccggttc ctcatgctca cgttgttact
    41341 accaccactc acaaaaccct ggcgggtccg cgcggcggcc tgatcctggc gaaaggtggt
    41401 agcgaagagc tgtacaaaaa actgaactct gccgttttcc ctggtggtca gggcggcccg
    41461 ttgatgcacg taatcgctgg taaagcggtt gctctgaaag aagcgatgga gcctgagttc
    41521 aaaacttacc agcagcaggt cgctaaaaac gctaaagcga tggtagaagt gttcctggaa
    41581 cgcggctaca aagtggtttc cggcggcact gataaccacc tgttcctggt tgatctggtt
    41641 gataaaaacc tgaccggtaa agaagctgac gccgctctgg gccgtgctaa catcaccgtc
    41701 aacaaaaaca gcgtaccgaa cgatccgaag agcccgtttg tgacctccgg tattcgtgta
    41761 ggtactccgg cgattacccg tcgtggcttt aaagaagccg aagcgaaaga actggctggc
    41821 tggatgtgtg acgtgctgga cagcatcaat gatgaagctg ttatcgagcg catcaaaggt
    41881 aaagttctcg acatctgcgc acgttatccg gtttacgcat aagcgaaacg gttaatctgt
    41941 tgaaaaaagg cttccttcgg gaagcctttc tacgttattg cgccatcaaa tctgccgtaa
    42001 ctgcgcctca acatacaaat agccaattcc cagcacctgc tgtgcgcggc ttaattgccc
    42061 aaagccaatt tgcgtcgctt tcacgctcgg tccttcgtcg cggtcgaacg ggttaaatcc
    42121 cgtctggcga ataatggtat taagccagtt ctcaccaaag gcacaactgc gaccgtacaa
    42181 ccaaatctga ttaatattga ggatgttgag gaagttatac agactcaaac caatggcgtt
    42241 ggcagagcga tcaacccaac tggtgatcca cggttctcca ctctgccagg cagcgattaa
    42301 ctgcgcggta gttagttttt caggatcaag ctgagtatta accggttgtg attttagcca
    42361 tacccgggcc tgttttttta atgcgcttaa cgaggcgacg gtttccaggc agccgtaacg
    42421 cccgcagtcg cagacgacgc catccggatt aacgatggtg tgaccaattt gcccgctacc
    42481 atacaaactg ccgcgataaa tttgctcgtt aatcacgaac gacgagccaa tgccgtaatc
    42541 aacgttgatc acgcagaaat cccgttcctg cgaattattt tgccatttct ccgccagcgc
    42601 cagcatcacg cagtcattat cgaccatcac ccgaatgccg agcttctctt ccagcagata
    42661 ctttacctca accggcgttg tccacggcgc ttgcggcatg gtttgcgaca cgccagtcac
    42721 cggatcaacc tgaccgtgga ttgccagagc cagattgatg gtgcggtccg gccacaattt
    42781 acggtggcga tgccagcatt tttcgatttc ggacagcagc gcctgcggcg ttggagcgtc
    42841 aatctgaaag cgttcaaatt cgcctttcgg acttaaacag gcattagcga cctgacactc
    42901 aatgctggtg ggcgtcacgt tcaggcacag cgtccagtct ccttccggcg caatcagcca
    42961 tgtaccgcta ctatgcccgc gcgtctggct ttcatcgtcg atattcacca cccgtttttc
    43021 gctttccagt tcctgcaaaa tattactgac tgccggaatc gaaatttgcg ccagccgggc
    43081 cagcgttgat ttattggcgc gcttttgccg gtacagcagt tccagaatca cgcatttgtt
    43141 atggtggcga atctgttgat tattaatgca ggctctcatc ttcactaaac cttgtttagt
    43201 taattgcgtg attattccgc gaaaacattg ccagattgtt caatacactg ccacaaatct
    43261 tttaattcag tatgtcttgt taatattgag ggcaccatga ctccagtaaa agtgtggcaa
    43321 gagcgcgttg agatcccgac ctatgaaacc gggccgcagg atatacatcc catgttcctg
    43381 gaaaatcgcg tttatcaggg atcgtccggc gcggtttatc cctacggcgt gaccgatacg
    43441 ctgagcgagc agaaaaccct gaaatcctgg caggcggtgt ggctggaaaa tgactacatc
    43501 aaagtgatga tcctgccgga actgggcggt cgggtgcatc gcgcatggga taaagtgaaa
    43561 cagcgcgatt ttgtctatca caatgaagtc attaaacctg cgctggtggg gctgctggga
    43621 ccgtggatct ccggcgggat tgagtttaac tggccgcaac accatcgccc gaccaccttt
    43681 atgcccgttg atttcaccct cgaagcccat gaagacggcg cacagacagt gtgggtaggc
    43741 gaaacggagc cgatgcatgg tttacaggtg atgacaggtt tcaccctgcg ccctgaccgg
    43801 gcggcgctgg aaatcgccag ccgcgtctat aacggcaacg ccacgccgcg tcatttcttg
    43861 tggtgggcca acccggcagt gaaagggggg gaagggcatc agagcgtctt cccgccggat
    43921 gtaacggcgg tgtttgatca cggcaaacgg gccgtctctg ctttccccat cgccaccggc
    43981 acttactaca aagtggacta ctccgctgga gtggacattt ctcgctataa aaatgtgcct
    44041 gttccaacct catatatggc tgaaaaatca cagtacgatt ttgttggcgc gtggtgtcac
    44101 gatgaagatg gcggtttgct gcacgttgcc aaccaccata ttgcgccagg taaaaaacag
    44161 tggagttggg gacacagcga atttggccag gcgtgggata agagtctgac cgacaataac
    44221 ggcccgtata tcgaactgat gaccggtatt tttgccgata accagcctga ttttacctgg
    44281 cttgatgcgt acgaagagaa gcgtttcgag cagtatttcc tgccttacca ttctctgggc
    44341 atggtgcaaa atgcctcccg cgatgcggtg ataaaactcc agcgtagtga gcgggggatt
    44401 gagtgggggc tgtatgccat ctctccgttg aacggatacc gcctggcgat ccgcgaaatc
    44461 ggcaaatgca acgcgttact tgatgatgcc gtggcactga tgccagcgac cgccatccag
    44521 ggcgtgttgc acggtatcaa tcctgacaga ctaaccattg agctctccga tgccgacggc
    44581 aatatcatac tgagttatca ggaacatcag ccgcaagagt tgccgttgcc ggacgtcgcc
    44641 aaagcgccac tgtcagcaca agacattacc agtacagatg aagcctggtt tatcggtcag
    44701 catctggagc aatatcatca tgccagccgt tcccccttcg attactacct gcgcggcgtg
    44761 gcgctggact tgctggatta tcgctgtaac ctggcgttgg cgatgctgga atataaccgc
    44821 gccgacttcc cgcaaacggt ggcgtatgcc actcaggcgc tgaaacgcgc acatgcgctg
    44881 aacaaaaatc cgcagtgcgg acaggccagt ttgattcgcg ccagtgctta cgaacgtcag
    44941 ggacaatatc aacaagccga agaggatttc tggcgggcgg tctggagcgg caatagtaaa
    45001 gcaggcggct attatggtct ggcacgactg gcggcgcgta atggtcactt cgatgctggt
    45061 ctggattttt gccaacaaag tcttcgcgcc tgcccaacca atcaggaagt gctttgcctg
    45121 cataatctgc tgctggtgtt aagtggtcgt caggacaacg cgcgtttgca gcgcgagaaa
    45181 ctgctgcgcg attatccgct gaacgccact ctgtggtggc tgaactggtt cgatggtcgt
    45241 agcgaatcag ccctcgcgca gtggcgcggt ctgtgtcagg gacgcgacgt taacgccctg
    45301 atgaccgccg ggcaactgat taactgggga atgcccaccc tggcggcaga gatgctgaac
    45361 gcactggact gccagcgcac gctgccgctt tatctgcagg cgagtttatt gccgaaagcc
    45421 gaacgcggcg aactggtcgc aaaagccatt gatgtcttcc cgcagtttgt ccgtttcccg
    45481 aatacgctgg aagaagtggc ggcgctggag agtattgaag agtgctggtt tgcccgtcat
    45541 ttactggcct gcttctacta caacaagcgc agctacaaca aagccattac tttatggcaa
    45601 cgttgcgtag agatgtcgcc ggagtttgcc gacggctggc gcgggttagc gatccatgcg
    45661 tggaataagc aacacgatta tgagctggcc gcgcgttatc ttgataatgc ttatcagctt
    45721 gcgccgcagg atgcacgtct gcttttcgaa cgggatttgc tggataagtt aagcggagcc
    45781 acaccggaga aacgactggc gcgtctggaa aataatctgg aaattgcgct gaaacgcgac
    45841 gacatgaccg cagaactgct caatttgtgg catctcacgg ggcaggcaga caaagcggcg
    45901 gacattctcg ccacgcgcaa attccacccg tgggaaggcg gggaagggaa gatcaccagt
    45961 caatttatcc tcaaccagtt attacgcgcc tggcagcatc ttgatgccag agagccgcag
    46021 caggccagcg aactgcttca tgccgcgctg cattatccgg agaatttaag cgaaggccgt
    46081 ttaccggggc aaactgataa cgacatctgg ttctggcagg cgatatgcgc caacgcgcag
    46141 ggtgatgaaa ctgaagcgat gcgttgttta cgtctggcgg cgactggcga tcgcaccatt
    46201 aacattcaca gttattacaa cgatcagccg gttgattatc tcttctggca aggaatggcg
    46261 ctgcgactgc tgggcgaaca acaaatcgca cagcaactgt ttagtgaaat gaaacagtgg
    46321 gcgcaagaga tggcgaaaac cagtattgag gcggatttct ttgctgtttc acaacctgac
    46381 ctgttgtcgc tgtatggcga tttacaacag cagcataaag aaaaatgcct gatggtggcg
    46441 atgctggcgt ccgcgggact cggggaggtt gcgcactatg aatctgctcg cgctgaattg
    46501 acggcgatta atccggcctg gccgaaagcg gcattattca ccactgtgat gccttttatt
    46561 tttaactacg ttcactaaac cctattaact gtaatatttg agcggcacgc gctgccgctc
    46621 acgctcaaat aattaaaatg agccgttgta aataaaaacc ctacaggagg cactatgcct
    46681 aaaaaaatga gaataacccg taatctatta ttaatagcta cgctattagg tagcgcacta
    46741 tttgccaggg ctgcggataa agaaatgacc attggcgcaa tataccttga tacccaggga
    46801 tattacgctg gcgtgcgtca gggcgttcag gatgcggcaa aagattcttc agtacaggta
    46861 cagttaattg aaactaacgc ccagggtgat atttcgaaag aaagtacctt tgttgatacc
    46921 ctcgtggcgc gtaatgtcga tgccattatt ttatcggcag tgtctgaaaa tggcagtagc
    46981 cgtaccgttc gtcgcgccag tgaagcgggt attccggtga tttgctacaa cacctgtatt
    47041 aatcaaaaag gcgtcgataa atatgtctcg gcgtatctgg tcggcgatcc gctggaattt
    47101 ggtaaaaaac tgggtaatgc tgccgccgat tattttattg ccaacaaaat tgaccagccg
    47161 aaaattgccg tcatcaattg cgaagccttt gaagtttgtg tgcagcgacg taaaggattt
    47221 gaagaagtat taaaatcccg cgttcccggc gcgcaaatag tcgctaatca ggaagggact
    47281 gttttagata aagcgatttc cgttggtgaa aaactgatta tctccacgcc ggatctcaac
    47341 gccattatgg gggaatcggg cggagcgaca ctcggcgcgg taaaagcggt acgtaatcaa
    47401 aatcaggccg gaaaaattgc tgttttcggt tcggatatga ccactgaaat tgctcaggag
    47461 ctggaaaaca atcaggtgtt gaaagcggtg gtggatattt ccggtaagaa aatgggcaat
    47521 gctgttttcg cgcaaacttt gaaggttatc aataaacaag ccgacggtga aaaagtgatt
    47581 caggtgccta tcgatctcta taccaaaacg gaagacggta aacagtggct ggcaacgcac
    47641 gttgatggtc tgccctaatc gctgattcgc agaggtccct atgttcacgg caacagaggc
    47701 agtcccggta gcaaaagtgg tggcaggaaa taagcgttac cccggcgtcg ttgcgttgga
    47761 taacgttaac ttcacgctca ataaaggcga agttcgtgcg ctgttaggca aaaacggcgc
    47821 gggcaaatcg accctcattc gaatgcttac cggcagtgaa cgtccggata gcggtgatat
    47881 ctggattggc gagacgcgac tggaaggtga cgaagctacg ctgactcgcc gtgccgctga
    47941 actgggggtt cgtgcggttt atcaggagtt aagtctggtg gagggactga ctgtggcgga
    48001 aaacctctgc ctcggtcagt ggccccgccg caacggcatg attgattacc tgcaaatggc
    48061 gcaggacgcc caacgttgct tgcaggcgtt gggcgttgac gttagccctg aacaacttgt
    48121 ttcaacgcta agcccggcgc aaaagcaact ggtggaaatt gcgcgggtga tgaagggcga
    48181 gccgcgcgtg gtcattcttg atgaacccac cagctcgctt gccagtgcgg aagttgaact
    48241 ggtgatcagc gcggtgaaaa agatgtcggc actgggcgtg gcggtgattt atgtcagcca
    48301 ccggatggaa gaaattcgcc gcattgcctc ctgtgccacc gttatgcgcg atggtcaggt
    48361 agcgggcgat gtgatgctcg aaaacacctc tacgcatcat attgtgtcgc taatgctcgg
    48421 gcgcgatcac gttgatattg cgccggttgc ccctcaggaa attatggatc aagccgtgct
    48481 ggaagtccgt gcgttacgcc ataagcccaa gctggaggat atcagcttta cgctacgtcg
    48541 cggcgaagtg ctcggcattg ctggcctgct gggggcaggg cgcagtgaat tgttgaaagc
    48601 catagttggg ctggagacgt atgaacaggg cgaaattgtt atcaacggcg agaaaatcac
    48661 gcgccccgat tacgacgaca tgctgaaacg cggcattggc tatacgccag aaaaccgcaa
    48721 agaagcgggg atcattccct ggctgggcgt tgacgaaaat acagtgctga ccaatcggca
    48781 aaaaatcagc gccaacggtg tgctgcaatg gtccaccatc cgccgcctga ccgaagaggt
    48841 gatgcagcgg atgacggtca aggccgccag tagcgaaacg cccatcggca cgctttctgg
    48901 cggcaatcag caaaaagtgg tgatcggtcg ttgggtctat gccgccagcc agattttgtt
    48961 gctcgacgag ccaacgcgtg gcgtcgatat cgaagccaaa cagcagattt accgtattgt
    49021 ccgcgagctg gctgccgaag gaaaaagcgt ggtgtttatc tccagtgaag tggaggagtt
    49081 gccgctggtg tgtgaccgca tcctgttatt acagcacggt acgttctcgc aggagtttca
    49141 ctcgccggtc aatgtggatg agctgatgtc cgccattctg tctgtgcact gatgaatttt
    49201 accgaggaac ctgaagatgt ctgcttcgtc attaccattg ccgcagggca agagcgtctc
    49261 gctcaaacaa tttgtcagtc gccatattaa tgagatcggt ttgctggtgg tgattgccat
    49321 tctttatctg gtcttctccc tgaacgcgcc tggctttatc tcattgaata accagatgaa
    49381 cgtgctgcgc gatgctgcca ccatcgggat cgccgcctgg gcgatgacgc tgattattat
    49441 ctccggtgaa attgatgtca gcgttgggcc gatggtggct tttgtttcag tgtgcctggc
    49501 gtttttgctg caatttgacg ttccgctggc gattgcttgt ctgctggtgt tgctgttagg
    49561 tgcgctgatg ggaacgctcg ccggggtgct gcgcggcgtg tttaatgtgc caagttttgt
    49621 tgccacgctg ggtttatgga gcgccctgcg cggaatgggg ctgtttatga cgaacgcctt
    49681 gccagtgcca attaacgaaa acgaagtgct ggactggctg ggcggacaat ttctcggtgt
    49741 gccggtatcc gcgctgatca tgatggtgtt atttgcgctg tttgtgttca ttagccgcaa
    49801 aaccgctttc gggcgctcgg tttttgctgt tggcggtaat gccactgcag cgcagttgtg
    49861 cggtattaac gttcgtcggg tacgcattct tatttttacc ctttcgggat tattagcggc
    49921 ggtgaccggc attttgttgg cggcgcgcct cggttccggt aacgcaggtg ccgcaaacgg
    49981 tctggagttt gacgtcatcg ccgcggtcgt ggtcggcggt acggcgcttt ccggcggtcg
    50041 cggctcgttg ttcggtacgc tgcttggcgt actggtgatt acgctaatcg gtaacggtct
    50101 ggtgctgcta gggattaact cctttttcca gcaggtggtg cgcggcgtca tcatcgtggt
    50161 ggcggtgctg gcgaatatct tgctgactca gcgaagcagt aaagcgaaac gctaaaccta
    50221 aacgcccctg gcgcgggtgc ggcagggatg aaaattaatc gtattgttaa tgagggattt
    50281 atgaaaacga tgctggcagc ttatttacca ggaaattcga ccgtcgatct gcgggaagtt
    50341 gcggtgccga cgccgggtat taaccaggta ctgatcaaaa tgaaatcctc cggaatttgc
    50401 ggaagcgatg tccactatat ctaccaccag caccgcgcta cggcggcggc acccgataaa
    50461 ccgttatacc agggatttat caacggtcat gaaccgtgcg ggcaaattgt ggcgatgggg
    50521 ctaggctgcc accattttaa agagggcgac cgtgtgctgg tgtatcacat ttctggctgt
    50581 ggtttttgcc cgaactgccg tcgtggtttt cctatctctt gtactggcga aggaaaagcg
    50641 gcttacggct ggcagcgtga cggcggccat gctgaatacc tgctggcgga agaaaaagat
    50701 ctgatcctgc tcccggacgc gctgagctat gaagatggtg cgtttatcag ttgcggcgtt
    50761 ggtacagcgt atgaagggat tttgcgcggc gaagtttccg gcagtgataa cgtgctggtg
    50821 gtcggtctgg ggccggtcgg catgatggcg atgatgctgg cgaaaggtcg cggtgcaaaa
    50881 cggatcatcg gcgttgatat gctgccggaa cgtctggcga tggctaaaca gttaggggtg
    50941 atggatcacg gctatttagc aaccaccgaa ggtctgcctc agattatcgc cgaactcacc
    51001 cacggtggcg cggatgttgc gctcgattgt tccggtaatg ccgcaggtcg cttgctggca
    51061 ctgcaatcca ctgctgactg gggacgcgtg gtttacattg gtgaaaccgg aaaagtcgag
    51121 ttcgaggtta gcgccgacct gatgcaccat caacggcgga ttatcggctc ctgggtgacc
    51181 agtctgttcc atatggaaaa atgcgcccac gatttaacgg actggaaact gtggccgcgt
    51241 aatgccatta cccatcgctt ctcactggaa caggcaggag atgcctatgc gctgatggcg
    51301 agcggtaaat gcgggaaagt tgtgattaac ttcccggatt aaggagtcag cggatgacca
    51361 tctatacctt atctcacggg ccgctaaagc tggacgtttc tgaccggggc ggcgtcatcg
    51421 aaggcttctg gcgtgacgcg acgccgctct tacgtcccgg taaaaaaagc ggtgtggcaa
    51481 ccgatgcctc ttgttttccg ctggtgccgt ttgcaaaccg ggtgagcggc aatcgttttg
    51541 tctggcaggg gcgtgagtat caactgcaac cgaatgttga gtgggatgcg cactatctgc
    51601 acggcgacgg ctggttgggc gagtggcaat gtgtctcgcg cagcgaagat agcttgtgtc
    51661 tggtgtatga acatcgcagc ggtgtttatc actatcgggt aagtcaggcg tttcatttaa
    51721 cggcggatac gctgacggtg acgctcgctg ttaccaatca aggggcagag acgctgccat
    51781 ttggtaccgg ctggcatcct tattttccgt tgtcgccgca aacgcggatt caggcacagg
    51841 cgagcggtta ctggctggag cgggagcagt ggctggcggg tgagttttgc gagcagctac
    51901 cgcaggaact ggattttaac cagctcacgc cgttgccgcg ccagtgggta aacaatggtt
    51961 ttgccggatg gaatggtcag gcccgcatcg agcagccgca ggagggttat gccatcatca
    52021 tggaaacgac gccgcctgca ccgtgttatt tcatctttgt ttccgacccg gcgtttgata
    52081 aaggatatgc gtttgatttc ttctgtctgg aaccgatgag tcatgcgccg gatgaccatc
    52141 atcgcccgga aggtggtgac ctcattgcgc ttgcaccagg ggaatcaaca acttcagaga
    52201 tgtcgttgcg ggttgcgttg ctgtaattta taaaatgccg gataaggcgt tcacgccaca
    52261 tccggcatct ttcctaacgg cgatcgagag aaatcgcccc cggcccggta attgccaaca
    52321 gcaggaatgc gccagcgata ctgacattct tccagaaatt aatcatattt ggcccaaccg
    52381 catcgccggt catatcccag taatggtgac caattaccgc tgtacccagc gtgtagaaaa
    52441 taaacagcac cgccagcgga cgggtgaaaa agccaagcac gattaatatc gcggcgggca
    52501 cttccataac taccgcaata atagctgcca gcatcggcat cggcgcgccc agcgaggcca
    52561 tatattggac cgtaccgtca aagcccatca ttttgggaaa accaaaaata atgaaaatta
    52621 agaccacggc gatacgggca attaataaca aaacggggcg ggcagctcca aaatcaaaat
    52681 aacgtagtgt gttcataacc aatccctttg caagataatg tgatttaaac gtaatacaca
    52741 ctctggcacc tcgccacgcc ccaggcattg agatattcgc taattatcct ggttacagtg
    52801 atttaagcgc gatgtgctca tctgtcagca gtttcgcatc aaacgttttg ccgctctgga
    52861 tccatttgcg gattaagcga atctcacgcc cctgattcag cgttaccgca ccgataagca
    52921 cgccgttttg cagattaaac caaatcgcct tctgagtttc cgggttgcca cgacaaagcc
    52981 agtcatcacc acgcatatca ccaataaact gtaagttatc actgtactga tcgctccaga
    53041 accacggcgg cggcagtcgc ggaagcggta gccccaacat tgcggaagcg gcaatttgcg
    53101 cctggtcatt ggcgttttcc cagctttcgc agcggtgtag tgcaccatta tcaagacggg
    53161 tgattgccac atcgccaccg gcaaagatcg cgggatcgca ggtgcggcaa gcctcatcaa
    53221 tgacaatgcc attggcagta tcaaggttgg cctcgcgagc cagttggtcg ttggcgctga
    53281 taccaatacc gtaaatcacc acatcggccc gaagcgtttc gccactttgc agcgtcagtt
    53341 ctactttttc accatcgacc acatgttcaa tggcattatt gagcagaatg cgcacaccag
    53401 cctgctgatg gcgctgtaaa agatagcgtt gcacgggcgg tggtgcatta cggcccatga
    53461 cggttgccgc cagttcaatc actgtcacct tacatccacg ctgcgtggcg ctggcagcca
    53521 gttccagacc aatagttccg gcaccgacaa tcacgactga ccgttcgggc tgcagaactt
    53581 ctcgcagtct ggcggcatcg ccggcatggc gcagagtaaa gcagcgttct cccagtgcat
    53641 caagcaacgg cagcggtctg gctgccgcgc cggttgctat aaaaagctga tcccagtgcc
    53701 agctttcgcc gttggttaac actaactctc gtgtgtcgcg gcccaatgtt ttgatggtta
    53761 caccggaatg cagatgaaca ttgttttcct gccaccagtg agcgggtaac acagactgca
    53821 actgtgggga atcttccagc aacatggatt tcgagagcgg ggggcgttca taaggaagat
    53881 gttgctcatc ggaaaacaga tgcagctcac cggtgaaccc ttgctggcga agcgaggccg
    53941 cagccattgc cgccgcttgc ccaccaccga caataatgat cgttttttct ttcatcgtgc
    54001 ttccttaaag atccagccca gccgctacgt ggcgaatgcc gcgaatcgct aaacccgcat
    54061 cagcgttgat catcacaccg cttaatgcgc gattattgcg ccgcgatgcc aacatcacat
    54121 acggacccgt aaaatccgcc ggttgcggga aaaattgcag cggtaatatg gcggcaattt
    54181 tctccggcgt cagagactgc attatcgagg tttcactttg cccgagcgcc tgtgggccgc
    54241 gcaggtcgct ggccatacca cacgggccga cgccattcac ccgcactttc ggtgccagtt
    54301 cataagccag ttggcgaata agtccggttg cggcatgttt actggcggtg tacagcgggc
    54361 caccgccgcc gggataccag gcggcatttg acagtgtgaa aatcatgctg ccttcactgg
    54421 cgattaacgc cggagcgcag gcttttgcgc ccagcaggta accgagtacg ttgacgttaa
    54481 acagctcgtg gaagccggtt tcgagcgtct ctgcgggagt attaaccagt gaggcattgt
    54541 gatcccagat gcccgcattg ccgataaaac aatccagttt gccagaacga gtcaggatct
    54601 gatcgatcgc gcgttgataa tcggtataac aggtcacgtt gccttccacc gccagaatat
    54661 gttcaccaaa tcgctgacgc agactggcga ctttcgccgc cgacagttcc aacgtggcaa
    54721 cctgcgcgcc ttcttcgata aatcgctcga ccagcgccag gcctaatccc gaaccgccgc
    54781 cggtaataaa gatggactcg ttatgcagat cgctcatggc tgcgcctccg gtaagtcgat
    54841 gaagatgtca ccaccttcaa cgtgtactgg ataagtggtt agcggatcgg tggcgggcag
    54901 gcataatgct ttccccgttt tcaggcaaaa actggcggcg tgcagcgggc actccaccgt
    54961 ggcgtcatct tccagatacc cttctgacat cgacgcatta ccatggctgc aacgatcgtt
    55021 aatggcataa aactcgccgc ctacgttgaa cagggcgatg acgggcgagg tatcgatccg
    55081 gagagcctca ccctccggca catccgcaac gggacacgca taaattcgat tcatcagaac
    55141 agtacactca ggttatggga agtgatcacc gcttgatcca ggacgatatc ccgttccagc
    55201 aagcgccagt tgtcatcttc cagacggcga actttgtcaa aacgagtccc gacatagaac
    55261 gcttcatcgc gctctttttg tgcccgataa agcagataat ttacccgcac agcaaatacg
    55321 tttgggatgt cggtttcact tacctggcag ttgctgatta agtgacgggt gcgtgacggc
    55381 ggttcttctg cccaggccat acccgtttcc agacgggcga ttcgccgttc cagctggtct
    55441 ttggtgtcat tgaaaatcca ggtcgtcggc ggctggacgc ctttgcggcg gtcgcgtgtt
    55501 tgcgcgttaa ctgtggtgcg catggtgtaa cgaatctctt cgtcgagctg tgccagccag
    55561 tcacgaaatt tccagtcatc cagcagactg gcttcgtgaa agagaaactg gctaatgcgg
    55621 tgatgtaact ccagtgaaac ttgcgcactc atttcatcac ctcctgctgg taagcggcgg
    55681 ttttatcgag cacttcctgc cagctttcgc tactcagaag atcggcccag cgttggtaca
    55741 ttccacgagc ggcagtttct gaaaagatat agttagtaat gccaggaatg ccgtcgtcgc
    55801 ggtgcttttc ctgaccaagc cccatttcca gacacagttt gctgttgcgg gcgcggtggc
    55861 ctttaagcaa tttctggatt tcacaccagt tctccgagtc atcctgctcg agaaaaccag
    55921 caggaccaaa agcacgagtg gcgctgtttt caaaagcagc tttaacttca tcggaggcgg
    55981 ctttgtcagt aatacagaac gcccacactt cgacttgatc agggccgcgc ggatgccaga
    56041 cgcggagcgt ggcagtgccg ttgagccatg aaagcgtggg gaaaatattg ttatgacccg
    56101 ccaggcgcag ggcgcgaact tcacctaaac gttgttctgc ttcggcatag gtttctcggt
    56161 aatagcttga aactgcgcca tcgacccaga cattagcatc cggtttttca gtaaagaaga
    56221 aaccgctgcc gtgaccgtcc tgaccaaact gcagcgcatc tttggcggtt tcccacaccg
    56281 ggcgggcagt ttgtccatca ccgagacgct tatcgctgcc atcatctttc gcccctaata
    56341 cctgaacggc agaagcatgg ctgaacagag catgatactg gtcactggcg aactgctctg
    56401 ccgggaattt ccagttgcag ttgatcaccc acttttgtac gccgccgaca atttcggtgc
    56461 cgccttcgcg acgatccagc atgccatcca gataccaggc aatgtcacca aggtaatcac
    56521 gcaggcccgg tgcgctggta tcccagttgc caaaaatcag ccctttataa ctctccacac
    56581 aaggaacttc gtttagtccc cagtgggatt tacacaaccc ttgtgggtag gcgcgaggtt
    56641 ccagcggtac atcgatcaac tcgccgttaa tgccataaga ccagccgtga tacgggcagg
    56701 taaaggcgcg cgtgttgccg caatctgcat aactcacacg catggcccgg tggcggcatt
    56761 ggttgagaaa cgccttgatg ctgccgtctt tctggcgcac cacgacaacc gcatcttctc
    56821 ccatgtaggt gttaaagaaa tcaccgggtt ttgggatctg gctttcgtgg gcgagaaata
    56881 gccagcaacg accgaaaatg cgctcaagct ccagttggta aatgtccggg tcggtataaa
    56941 tacgcggagt gacccgaccg ttttgggtgt caatcagttg gtaaatgttc aaatctgagg
    57001 gtgtggtcat attttttaat cctgaaagat aagatgtatt gaccttctat ttttgtgcca
    57061 taaggatgtt gctggttggc tgctaatatg tgaaatagtt aatttctacc agctgagacg
    57121 ttttttcgat aacaagggga aggtgatgga actacggcat ttacgctatt tcgtcgcagt
    57181 ggcgcaggca ctgaacttta cccgtgcggc ggaaaaactg catacctcac agccttcgtt
    57241 aagcagccag atccgcgatc ttgaaaactg tgtcggtgtt ccgttactgg tgagggataa
    57301 gcgcaaagtc gcattgacgg cggcgggaga atgttttctc caggacgcgc tggcaatcct
    57361 cgaacaagcg gaaaatgcca aattacgggc gcggaaaatt gttcaggaag acagacaatt
    57421 aaccattggc tttgtgccat cggcggaagt gaatttactg ccaaaagtat taccgatgtt
    57481 tcgtctcaga cagccagaca ccttaattga gctggtgagt ttaatcacca cggaacagga
    57541 agaaaaaatt cgccgtggtg aactcgacgt cggcttaatg cgccatcccg tttatagccc
    57601 ggagattgat tatctggagc tttttgacga accattagtg gtggtgttac cggttgatca
    57661 ccctttagca catgaaaaag agatcactgc cgtgcaactg gatggcgtga atttcgtcag
    57721 tactgatcca gcgtattccg gttcgcttgc gccgatcgtt aaagcgtggt ttgcgcaaga
    57781 aaacagccag ccaaatatcg tccaggtggc aacgaatatt ctggtgacca tgaatctggt
    57841 ggggatgggg ctgggcgtca ctttgatacc cggttatatg aataatttta ataccggcca
    57901 ggtggtattt cgacccattg ccggaaatgt gcctgccatt gctttactga tggcgtggaa
    57961 gaaaggggag atgaagccgg cattacgcga tttcatcgcc attgtgcagg aacgtttggc
    58021 atgcgtaacg gcataattac gcattatttt tgcaacatgc gtcgcggctc gcagtttttt
    58081 agtgcttgtg aactggcgtt acagacatca ggaagcaggc tcgaatattc ttatttttca
    58141 acttgcacca acattcgatt aaccccagac taacgcctcc tgacgggagg gactcatggt
    58201 tttgcaatcc acgcgctggt tggcgctcgg ttatttcaca tactttttta gttacggcat
    58261 ttttctacct ttctggagcg tctggcttaa aggtattggt ttaacgccag aaaccatcgg
    58321 cctgttattg ggggcgggtc tggttgcccg tttcctcggg agtttgctca tcgcgccccg
    58381 cgtcagcgat ccttcccgcc tgatttccgc cttgcgcgtg ctggcactgc tgacacttct
    58441 ctttgctgtc gccttctggg cgggggcgca cgtagcgtgg ctgatgctgg tgatgattgg
    58501 ctttaacctc tttttctcac cgctggtacc gttgaccgat gcactggcga atacgtggca
    58561 aaagcagttc ccgcttgatt acggcaaagt gagactgtgg ggctcggtag cgtttgtcat
    58621 tggctcggcg ctgacgggca aactggtcag tatgtttgat tatcgggtga tcctcgcgct
    58681 gttgacgttg ggcgtggcat ccatgctgct cggctttctc atccgtccga cgattcagcc
    58741 acaaggggca agccgccagc aggagagcac cggttggtct gcgtggttgg cgttggttcg
    58801 ccagaactgg cgctttctgg cctgcgtttg tttattgcag ggggcacatg cggcctatta
    58861 cggttttagc gccatttact ggcaggcagc tggctactcg gcctcggcgg tgggctattt
    58921 gtggtcgctg ggcgtggtgg cagaagtcat tatctttgcg ctgagtaata agcttttccg
    58981 ccgttgtagc gcccgtgata tgttgctgat ctcggcagta tgtggggtat tgcgttgggg
    59041 aattatgggg gcaaccactg agctactgtg gttgattatg gtgcaaattt tgcattgcgg
    59101 caccttcacc gtgtgccatc tggccgctat gcgctacatt gctgctcgcc agggtagcga
    59161 agtcatccgt ttacaggcgg tttactctgc cgtcgcgatg ggcggcagta tcgccatcat
    59221 gaccgttttc gccggtttcc tgtatcaata tctcggccac ggcgtgttct gggtgatggc
    59281 gctggtggcg cttccggcaa tgtttttgcg cccgaaagtt gttccctcat gctgattcga
    59341 gcattttgcg gatctgctcc tgttgatgtg ttgtcaacgt caggtccgta tagatcagcg
    59401 gtggtgaaaa gagcggtaac ggcatggtat aaggcgcaat aatcagtgcc gcgccgcgcg
    59461 gagcgcctgt ctgcaaaaat gcctttaccg acatatgttt aatgttgagc ggcagtaacg
    59521 ttatttcgcg tagctgctgc tcaatctgcg cttctcgctc gctatcattc ccggtcagta
    59581 gaataatctg tttctcatgc aggtcgtttt cctgcattag ccaggcaccg aaaatcaccg
    59641 cgaccagacc gctttcctca tcagaaagat ggacgccgta ttcactttca aatccggcca
    59701 gcgccgcgcg ggtggtgcgc accaggcgtg gatacaggcg ggcgaactct tccggcaggg
    59761 tgttatcaat accgatggca aacaaactgc gatttaacgc ctgggcgagg tgggtataaa
    59821 gctgatcgca caacccctgt tcatcataaa aacgaacatt tcccagctca cgaaaatggt
    59881 ttaccagacg tttgatagac tgacgcagtt gtctgtcccg ctgatgcgca tcccgcagtg
    59941 gatcgggaac ccgcaacatg gaaaaaagta atgccatgaa cagtggctca tcaggcggta
    60001 caggctggag cgcccgacgc tgccagtggc gtccaatttc ctgcgctacc tgaaattcaa
    60061 ggcaggattc cgcccagcga cgttggagcg gattaaactg aggcgtaatt ccagcgtggt
    60121 gttgcagcaa acaatattgc agatacagac acaggaaatg aatatcgcgc gtttcaaagc
    60181 gtttttgcag ccgtcgggag cagagattca ctaacgcttg tagattggta tcgtcgtaaa
    60241 agttacgcgc aattccgcgc cgcttcagtt cactcttcag ggcgggggtg aaatggctgg
    60301 taataaatga cggacacaga cggaaaccac gtcgtagcca gtgaaataaa cacaaacgtt
    60361 ggttaagcac tgtaccttca acccggtagc taccgtcata accagtagtc agtgtgagtt
    60421 gatgatagcg caggatctct cgtcctgttt cgctgatatc aagactggca atatcatcat
    60481 ccacaccatt aagctcgctg aaagttgccg tggtggcggt caaccccggc tgaaagagcg
    60541 tcagcaagat ctggcagcgg cgctggggag ccgaaaggac agatggtgga gcaagcgtag
    60601 gcatcatctg tagatctccc ataagcataa ttgataagaa tagctaaagt ttgctcaggg
    60661 aaatggcgaa gggaatgcta atcatcagaa atgttggcaa gcgtcacaga atttttctca
    60721 tcttaaattg ttctgaccag tggattagca tgtcttaagg tggttttgtg aatgattatc
    60781 gtgctagcga tcatgggtta gttctgcgga ttcaacgcgc taaggataaa atccaccatc
    60841 tgttcgcgat aaacatcgcc gtgacgatcg gaaaaagcat caatgtgttc gccatccggg
    60901 attaggatca accgttttgg ctcttttgcc aggctataca acttttcgct gtgctgccat
    60961 gggataacgt gatcagcttt accgtgaatg agtaaaagcg ggatcgggct gacgctggcg
    61021 atgtaatttt cgccgctgta actctcatca agtaagtagc cactgccggg gatcatctgg
    61081 ttggcgatgg tcgcataaga ggcaaatgtg gagtcgagga tcaccgcacg tatgccttca
    61141 cgatcaccct gaccaataac atccagaata ttcgccccgc caatactctg cccgaacagc
    61201 accagccgtt gtgggtttac atcactgcga tggcgcacca cattgatggc actttgcgta
    61261 tcgtccagca atccggcctg ggacggcgtg ccttttgatt taccaaaccc gcgataatca
    61321 aacataaaaa cgttgaaatt acgctcgggt aaccaactga ccagcggcca gtgggcggac
    61381 atatttccgg cattgccgtg agcatgaata atggtagcaa tggcgttatc agcagggccc
    61441 gtcgaagaag gaataaacca gccttgcaga cgagtaccgt ccttagccgt aaattcgacg
    61501 gattccgccg accaggggtc gggaccgtat attttatcgt caggataata gaagaagttg
    61561 atggcgacgc gcggcactaa ataaacgcag aaggcaacaa caaagagaat aaacagaatt
    61621 ttgagaatgc gtttgttcac tggcagcgcc ataacctttc cttgcgactt ctttatcatc
    61681 cattaatcgg ggaaagatgg tgggagagtg acgaaagaaa gtaaagcggt gaggaagtat
    61741 ttcggaatag cgcctgaaag gcgagggcgg gtgagtgata tcacccgcct gagtcattaa
    61801 cgcttcagag cgtcgcttaa ctcgtcacgc atgttcgcca gcatggcttt aacaacgcgc
    61861 gggttaccag caacgatgtt accggtcagc atatagttat gaccaccggt gaagtcgctg
    61921 acgatgccgc ccgcttcacg aaccagcagc tcgcctgccg cgaaatccca cgggcgcaga
    61981 ccgatttcaa agaaaccgtc aacgcgaccc gcagcaacgt aagccagatc cagcgccgca
    62041 gaaccggtac gacggaagtc tgcacattcg ttgaacagtt tgccgacgat gttgatgtag
    62101 gtggtggcgt actgttttgc tttgaacggg aagccggtcg ccagaatagt accgtcgaga
    62161 tcgcgagcgg tgctgccgcg cagacggtag ccgttcagct gtgcgccctg accgcgagtg
    62221 gcggtgaaca gttcgttacg cataggatcg tataccacag caacttcggt gcggcctttg
    62281 atacgaacgg cgatagatac cgcgaagtgc ggcagacgtt tgataaagtt ggtagtgcca
    62341 tccagtggat cgataaccca ttgaacatcc tgatcagtac cttcaagttc accgctttct
    62401 tcggtgatga tggtgtgctg tgggtaagat ttacgaatcg tgtcgataat caccgcttcg
    62461 gcagctttat ctacgttggt cacgaagtcg ttactgcctt tctggctcgc ttctacagcg
    62521 tccggggttt catagttttt ggcaattaaa ttacccgcct tgcgcgctgc gcgcacggcg
    62581 atgttcagca tcggatgcat cggtctctct cactggatgt taaagaacgg gaaaacggcg
    62641 cagagtatag cagcgagatc ggcatctgtc ttcgttttat gataagatgc gcgaataatc
    62701 tttagacgaa gaaagacaat gctgcaaaat attcgaattg tgctggtgga gacgtcacac
    62761 accggcaata tgggttctgt tgcccgtgcc atgaaaacaa tgggattaac caatctgtgg
    62821 ctggttaatc cactggtgaa acccgactcc caggcgattg ccctggcagc aggggccagc
    62881 gatgtgattg gtaatgcgca catcgtcgat acgctcgacg aagcgttggc tggttgtagc
    62941 ctggtggtgg gcaccagcgc acgttctcgc acgctgccgt ggccgatgct cgacccgcgc
    63001 gaatgcggtc tgaaaagcgt cgctgaagcg gcaaataccc cggtggcgct ggtgtttggt
    63061 cgcgagcgcg tcggcttgac caatgaagag ctgcagaaat gccattatca tgtcgcgatt
    63121 gcggctaacc cggaatacag ttcgctgaac ctggcgatgg cggttcaggt tattgcctat
    63181 gaagtgcgca tggcctggct ggcaactcag gaaaatggcg agcaggtcga gcatgaagag
    63241 acgccgtatc cgctggtcga tgatctggag cgtttttatg gtcatctgga gcaaacgctg
    63301 ctggcaaccg gttttatccg tgaaaaccat ccggggcagg tgatgaataa attgcgccgt
    63361 ctgtttaccc gtgcacgccc ggaaagccag gaattgaata tcctgcgcgg gattctggct
    63421 tctattgagc agcagaataa aggtaacaag gccgaataac agtggttgcc tgatgcgatg
    63481 cttaacgcgt cttatcaggc ttgtaagtgc acggaatccc aggtcggata aggtgttcac
    63541 accgcatccg acaacaggta caaacgccac gataaaaaaa tggcactgaa ggttaaatac
    63601 ccgactaaat cagtcaagta aatagttgac caatttactc gggaatgtca gacttgaccc
    63661 tgctatgcaa tacccccact tttacaataa aaaaccccgg gcaggggcga gtttgaggtg
    63721 aagtaagaca tgagactgac atctaaaggg cgctatgccg tgaccgcaat gcttgacgtt
    63781 gcgctcaact ctgaagcggg cccggtaccg ttggctgata tttccgaacg tcagggaatt
    63841 tccctttctt atctggaaca actgttttcc cgtctgcgta aaaatggtct ggtttccagc
    63901 gtacgtggac caggcggtgg ttatctgtta ggcaaagatg ccagcagcat cgccgttggc
    63961 gaagtgatta gcgccgttga cgaatctgta gatgccaccc gttgtcaggg taaaggcggc
    64021 tgccagggcg gcgataaatg cctgacccac gcgctgtggc gtgatttgag cgaccgtctt
    64081 accggttttc tcaataacat tactttaggc gaactggtta ataaccagga agtgctggat
    64141 gtgtctggtc gtcagcatac tcacgacgcg ccacgcaccc gcacacaaga cgcgatcgac
    64201 gttaagttac gcgcttaata aaaagaattc agaatcaggc cggagtgcta aacactccgt
    64261 aaacacggtc gtacatccag ccggtagcct ggttccttgc attgagtgat gtacggagtt
    64321 tatagagcaa tgaaattacc gatttatctc gactactccg caaccacgcc ggtggacccg
    64381 cgtgttgccg agaaaatgat gcagtttatg acgatggacg gaacctttgg taacccggcc
    64441 tcccgttctc accgtttcgg ctggcaggct gaagaagcgg ttgatatcgc ccgtaatcag
    64501 attgccgatc tggtcggcgc tgacccgcgt gaaatcgtct ttacctctgg tgcaaccgaa
    64561 tctgacaacc tggcgatcaa aggtgcagcc aacttttatc agaaaaaagg caagcacatc
    64621 atcaccagta aaaccgaaca caaagcggta ctggatacct gccgtcagct ggagcgcgaa
    64681 ggtttcgaag tcacctacct ggcaccgcag cgtaacggca ttatcgacct gaaagaactg
    64741 gaagcagcga tgcgtgacga caccatcctc gtttctatca tgcacgtgaa taacgaaatc
    64801 ggcgtggtgc aggatatcgc ggctatcggc gaaatgtgcc gtgctcgtgg cattatctat
    64861 cacgttgatg caacccagag cgtgggcaaa ctgcctatcg acctgagcca gttgaaagtt
    64921 gacctgatgt cattctccgg tcacaaaatc tatggcccga aaggtatcgg tgcgctgtat
    64981 gtgcgtcgta aaccgcgcgt acgcatcgaa gcgcaaatgc acggcggcgg tcacgagcgc
    65041 ggtatgcgtt ccggcactct gcctgttcac cagatcgttg gtatgggcga agcctatcgc
    65101 atcgcaaaag aagagatggc gaccgagatg gaacgtctgc gcggcctgcg taaccgtctg
    65161 tggaacggca tcaaagatat cgaagaagtt tacctgaacg gtgacctgga acacggtgcg
    65221 ccgaacattc tcaacgtcag cttcaactac gttgaaggtg agtcgctgat tatggcgctg
    65281 aaagacctcg cggtttcttc aggttccgcc tgtacgtcag caagcctcga accgtcctac
    65341 gtgctgcgcg cgctggggct gaacgacgag ctggcacata gctctatccg tttctcttta
    65401 ggtcgtttta ctactgaaga agagatcgac tacaccatcg agttagttcg taaatccatc
    65461 ggtcgtctgc gtgacctttc tccgctgtgg gaaatgtaca agcagggcgt ggatctgaac
    65521 agcatcgaat gggctcatca ttaatcggta tcggaatcag gagaatttat aatggcttac
    65581 agcgaaaaag ttatcgacca ttacgagaat ccgcgtaacg tgggttcctt tgacaacaac
    65641 gacgagaacg tcggcagcgg catggtgggt gcaccggcct gtggcgacgt gatgaagttg
    65701 cagattaaag tcaacgatga aggtatcatt gaagacgcgc gttttaaaac ttacggctgc
    65761 ggttctgcta tcgcttccag ctccctggtc accgaatggg tgaaagggaa gtctctcgac
    65821 gaagcgcagg cgatcaaaaa caccgatatt gctgaagaac ttgaactgcc gccggtgaaa
    65881 attcactgtt ctattctggc agaagacgcg atcaaagccg ccattgcgga ctataaaagc
    65941 aaacgtgaag caaaataaga gttgaggttt ggttatgtcg attacactga gcgacagtgc
    66001 agcagcgcga gtaaatacct ttctggctaa ccgcggcaaa gggtttggcc tgcgtctggg
    66061 cgtgagaacc tccggatgtt caggtatggc ttatgtactg gaatttgttg acgaaccgac
    66121 gccggaagac atcgtgtttg aagacaaagg cgtgaaagtc gtggtcgatg gcaaaagcct
    66181 gcaatttctg gacggtacgc agctggactt cgtaaaagaa ggcctgaacg aagggtttaa
    66241 attcactaac ccgaacgtca aagatgagtg tggttgcggc gaaagcttcc acgtttgatg
    66301 cgcataccga taaccccacc gtggtcgcct gcgcgtgggg tttgttttac ctgattcgcc
    66361 gttatcgcgg cggatcgcag ccctgagaat gttatggatt acttcaccct ctttggcttg
    66421 cctgcccgtt atcaactcga tacccaggca ctgagcctgc gttttcagga tctacaacgt
    66481 cagtatcatc ctgataaatt cgccagcgga agccaggcgg aacaactcgc cgccgtacag
    66541 caatctgcaa ccattaacca ggcctggcaa acgctgcgtc atccgttaat gcgcgcggaa
    66601 tatttacttt ctttgcacgg ttttgatctc gccagcgagc agcatactgt gcgcgacacc
    66661 gcgttcctga tggaacagct ggaactgcgc gaagaactgg acgagatcga acaggcgaaa
    66721 gatgaagcgc ggctggaaag ctttatcaaa cgtgtgaaaa agatgtttga tacccgccat
    66781 cagttgatgg ttgaacagtt agacaacgag acgtgggacg cggcggcgga taccgtgcgt
    66841 aagctgcgtt ttctcgataa actgcgaagc agtgccgaac aactcgaaga aaaactgctc
    66901 gatttttaat ttctggaagc taaacatggc cttattacaa attagtgaac ctggtttgag
    66961 tgctgcgccg catcagcgtc gtctggcggc cggtatcgac ctgggcacaa ccaactcgct
    67021 ggtggcgaca gtgcgcagcg gtcaggccga aacgttagcc gaccatgaag gccgtcacct
    67081 gctgccatct gttgttcact atcaacagca agggcattcg gtgggttatg acgcgcgtac
    67141 taacgcagcg ctcgacaccg ccaacaccat tagttctgtt aaacgcctga tggggcgctc
    67201 gctggctgat atccagcaac gctatccaca tctgccttat caattccagg ccagcgaaaa
    67261 cggccttccg atgattgaaa cggcggcagg actgctgaac ccggtgcgcg tttctgcgga
    67321 catcctcaaa gcactggcgg cgcgggcaac tgaagccctg gcaggcgagc tggatggtgt
    67381 agttatcacc gttccggcgt actttgacga tgcccagcgt cagggcacca aagacgcggc
    67441 gcgtctggcg ggccttcacg tcctgcgctt acttaacgaa ccgaccgctg cggctatcgc
    67501 ctacgggctg gattccggtc aggaaggcgt gatcgccgtt tatgacctcg gtggcgggac
    67561 gtttgatatt tccattctgc gcttaagtcg cggcgtgttt gaagtgctgg caaccggcgg
    67621 tgattccgcg ctcggcggcg atgatttcga ccatctgctg gcggattata ttcgcgagca
    67681 ggcgggcatt cctgatcgta gcgataaccg cgttcagcgt gaactgctgg atgccgccat
    67741 tgcagccaaa atcgcgctga gcgatgcgga ctctgtgacc gttaacgttg cgggctggca
    67801 gggcgaaatc agccgtgaac aattcaatga actgatcgcg ccactggtaa aacgaacctt
    67861 actggcttgt cgtcgcgcgc tgaaagatgc gggcgtagaa gctgatgaag tgctggaagt
    67921 ggtgatggtg ggcggttcta ctcgcgtgcc gctggtgcgt gaacgagtag gcgaattttt
    67981 cggtcgtcca ccgctgactt ctatcgaccc ggataaagtc gtcgctattg gcgcggcgat
    68041 tcaggcggat attctggtgg gtaacaagcc ggacagcgaa atgctgttgc tggatgtgat
    68101 cccgctgtcg ctgggcctcg agaccatggg cggcctggtg gagaaagtga tcccgcgtaa
    68161 taccacgatt ccggtggccc gcgcccagga tttcaccacc tttaaagatg gtcagacggc
    68221 aatgtctatc catgtgatgc agggtgaacg tgaactggtg caggactgcc gctcgctggc
    68281 gcgttttgca ctgcgtggta tcccggcgct accggctggc ggcgcgcata ttcgcgtaac
    68341 gttccaggtc gatgccgacg gtcttttgag cgtgacggcg atggagaaat ccaccggcgt
    68401 tgaggcgtct attcaggtca aaccgtctta cggtctgacc gatagcgaaa tcgcttcgat
    68461 gatcaaagac tcaatgagct atgccgagca ggacgtaaaa gcccgtatgc tggcagaaca
    68521 aaaagtagaa gcggcgcgtg tgctggaaag tctgcacggc gcgctggctg ctgatgccgc
    68581 gctgttaagc gccgcagaac gtcaggatat cgacgatgct gccgctcacc tgagtgaagt
    68641 ggcgcagggc gatgatgttg acgccatcga acaagcgatt aaaaacgtag acaaacaaac
    68701 ccaggatttc gccgctcgcc gcatggacca gtcggttcgt cgtgcgctga aaggccattc
    68761 cgtggacgag gtttaatatg ccaaagattg ttattttgcc tcatcaggat ctctgccctg
    68821 atggcgctgt tctggaagcg aatagtggtg aaaccattct cgacgttgcg ctgcgtaacg
    68881 gtatcgagat tgaacacgcc tgtgaaaaat cctgtgcttg caccacctgc cactgcatcg
    68941 ttcgtgaagg ttttgactcg ctgccggaaa gctcagagca ggaagacgac atgctggaca
    69001 aagcctgggg actggagccg gaaagccgtt taagctgcca ggcgcgcgtt accgacgaag
    69061 atttagtggt cgaaatcccg cgttacacta tcaaccatgc gcgtgagcat taacagaggt
    69121 tagtatggga cttaagtgga ccgatagccg cgaaattggc gaagcactgt acgatgcgta
    69181 tcccgatctt gatccgaaaa cggttcgatt caccgatatg catcagtgga tttgcgatct
    69241 ggaagatttc gacgacgacc cgcaggcatc caacgaaaaa atcctcgaag cgattttgtt
    69301 ggtctggctt gacgaggccg agtaaatgaa cgggctgcct gggggtagcc cgttttgctg
    69361 ttaaacgaat aaggataact aaaatgacag aagcgatgaa aattaccctc tctatccaac
    69421 ctgccgatgc gcgctgggga gaaaaagcaa cttacagcat taataatgat ggcattaccc
    69481 tgcatttgaa cggggcagac gatctggggc ttatccagcg tgcggcgcgc aagattgatg
    69541 gtctgggcat caagcatgtt cagctaagcg gagaaggctg ggatgcggat cgctgctggg
    69601 cattctggca aggttacaaa gccccgaaag gcacgcgtaa agtggagtgg ccggatctgg
    69661 acgatgccca gcgccaggaa ctggataacc gcctgatgat catcgactgg gtgcgtgaca
    69721 ccatcaacgc accggcagaa gaactggggc catcgcaact ggcacagcgt gctgttgatc
    69781 tgatcagcaa tgtcgcgggc gattgtgtga cttaccggat caccaaaggc gaagatctgc
    69841 gtgatcaagg ttatatgggg ctgcacaccg tcggacgcgg ttcagaacgt tctccggtat
    69901 tgctggcgct ggattacaac ccaactggcg ataaagaagc gccagtgtac gcgtgcctgg
    69961 ttggtaaagg catcactttt gactccggcg gctacagcat caaacagacc gcatttatgg
    70021 actcgatgaa gtcggacatg ggcggcgcgg caacggttac cggggcgctg gcgtttgcca
    70081 ttacgcgcgg actgaacaag cgcgtgaagc tgttcctctg ctgtgcggat aacctgatca
    70141 gcggcaacgc gttcaaactg ggcgatatta ttacctatcg caacggtaaa aaagttgaag
    70201 tgatgaacac tgatgcggaa gggcgtctgg tgctggccga tggcctgatt gatgccagtg
    70261 cgcagaaacc ggaactgatc attgatgcgg cgaccctcac cggggcggcg aaaactgcgc
    70321 tgggtaatga ttatcacgcg ctgttcagtt ttgacgatgc gcttgccggt cgcttgctgg
    70381 cgagtgccgc gcaggagaat gaaccgttct ggcgtctgcc gctggcggag ttccaccgca
    70441 gccagctgcc gtctaacttt gccgaactga acaataccgg aagcgcggcg tacccggcag
    70501 gcgcgagcac ggcggcgggc ttcctgtcgc actttgttga gaactatcag caaggctggc
    70561 tgcatatcga ctgctcggcg acttaccgta aagcgccggt tgaacagtgg tctgcgggtg
    70621 ctacgggact tggtgtgcgc acgattgcta atctgttaac ggcgtaaact aatatgccgg
    70681 atgcggcgta aacgccatat ccggcctaca aagtattgca aattcaacaa attgtgaatc
    70741 ccttgtaggc ctgataagta tggcgcatca ggcacttgtg ccccgaacgt tgaatgaatt
    70801 gtggttctta tgtccgaaac aaaaaatgaa cttgaagacc tgctggaaaa agcagcaacc
    70861 gaaccggcgc accgcccggc ctttttccgt actctactgg aatccaccgt ctgggtgccg
    70921 ggtacggcgg cgcagggcga ggctgtggtt gaagatagcg cgcttgattt acagcactgg
    70981 gaaaaagaag acggcaccag cgtcattcct ttttttacct cgttagaagc acttcaacag
    71041 gcggttgaag acgaacaggc atttgtcgta atgcccgttc gcacattgtt tgagatgacc
    71101 cttggcgaaa cgctcttcct taatgccaaa ctgccaaccg gtaaagaatt tatgccgcgt
    71161 gaaatcagtt tgttgattgg tgaagaagga aatccgctga gcagccagga agtactggag
    71221 ggcggtgaat cgctgatatt atcggaagtc gcagagccac cagcacaaat gattgattct
    71281 ctcaccacct tatttaaaac tattaagccg gtgaagcgtg cttttatttg ttcaattaaa
    71341 gagaacaaag aggcacagcc taatttactt attggcattg aagccgatgg tgatatcgaa
    71401 gaaattattc aggcggcggg aagtgtagcg accgatacat tacctggcga tgaacccatc
    71461 gatatttgtc aggtgaaaaa aggggaaaaa ggaattagcc actttattac cgaacatatt
    71521 gtgccattct atgaacgtcg ctggggtggt tttttgcgtg actttaaaca gaaccggata
    71581 atctaaaata tgccgcccca aagggcggca ttcgggctta cctgctgttc tgaaggttgt
    71641 taaccaccaa taaattgttg ccggagagac tccggttatt atttacctcg gttaacagcg
    71701 caccagaaac aataagtacg atacaaaagc tccgtatctt cattgtgcgg tccatgcgaa
    71761 gaccgcatca cgacagcacc actggcgata ttgccgcgat agcaagcgct gtgaaacacc
    71821 tgcatttacg gccatggaac atcctttcct taagccagcg cccgtttgcg aaacggcgga
    71881 aagggccggt gtcgataata cgctaaataa acaatgatta ctctctttcg cttgacaaaa
    71941 agagagttac tggcgagtat tgctttgctg tgaagcacct gcgttgctca tgcaacacaa
    72001 gccaatctgc tggaaaggcc gcgaaccaaa ccagcaacaa aaaaccgcct gattttggcg
    72061 gttttttgtt gtttaaagaa agtgaattta cacgtttaag taatatcttt taccgattag
    72121 tatttttaat attgagctgg atttgtttat atttgtccga attcggacta ataagccagg
    72181 ttattttatt accgaacata ttgtgccatt ctatgaacgt cgctggggtg gttttttgcg
    72241 tgactttaaa cagaaccgga taatctaaaa tatgccgccc caaagggcgg cattcgggct
    72301 tacttgctgc tctgaagttt gttaaccacc agtaaattgt cgccggagag actccggtta
    72361 ttatttacct cggttaacag cgcaccagaa acaataagta cgatacaaaa gcaccgtatc
    72421 ttcattgtgc ggtccatgcg aagaccgcat cacgacagca ccactggcga tattgccgcg
    72481 atagcaagcg ctgagacgcg cttgctctaa cggtcgcgga acatcctttc cttaagccag
    72541 cgcccgcttg cgagacggcg gaaagggccg cagtggataa tacactaaca gaacaataat
    72601 aactctcttt tgcttgacaa aaagagagtt actggcgagt attgtgtccg ctgagacgcg
    72661 cttgcattac tacggtaata caacctgctg gaaaggccgc gaaccagacc agcaataaaa
    72721 aaccgccaaa ttcggcggtt ttttattgcc tgtaaaaagc ttatttcaat ggctcaaccg
    72781 gtaaatctgc ccgtgcgccc cattcactcc atgcgccgtc gtacagtttc acgtttggca
    72841 catccagcgt cgcgagtgcc aacaaaacca cggctgccgt tacaccagag ccgcagctga
    72901 cgataatcgg tttgtcatag ctgacgccgc gaccaaaaaa tatcgcatcc agttcatcgg
    72961 tcgtttttaa ttcgccttcg cgcaccagtt ccgtccacgg aacgttcaat gcaccgggaa
    73021 tatgtccgcg acgtaaacct gggcgaggtt catcaacttc tgcgttaaaa cgtgcagccg
    73081 ggcgggcatc aataatttgc gccgtatttt catggcttgc caataacaca tcggtgactt
    73141 tcaccacggc ttcaggatta aacgtggcgt taaactctcc ttccggcagc tctactgcac
    73201 cttcttctaa cagcagaaca tcgcgctgcc agcctgcaag tccacccccc agaatcgaca
    73261 ctttctctac accaaaggtg cgcagcatcc accatgctcg tggggctgag aaaagattac
    73321 cttcgtcata gacaatcagg tgcttatcct ggttaacgcc taactcacgc atcgccacgg
    73381 cgaacgtttc cgggcgcggc agcatgtgcg gaagcgggga agtgtgatca gaaagcgctt
    73441 cgatatcaaa aaacactgcg ccgggaatat gtccattcag atactcctga gcaacgttac
    73501 gatcttcctg tccaggcgac gccatgcggg catcgataat ctgaatttcc gggtcatcaa
    73561 tatgttcggc gagccagtcg gctcctacaa accatgtcgt ggacataggc atctccattt
    73621 ttgccggggt taggctaaat tgtcggatgt ttagtgaaaa gcgacaagca aaagaggctg
    73681 atttggctgt ctgagccaca attctcacta aaattcggat tgtatgggcg tgatactgaa
    73741 ttacataacg taaattctca cgcataataa ttattcgacg ttgctaacgg gccattgtgg
    73801 cagggatgaa aaatgaaaaa gttacgcgta gccgcctgca tgctaatgct ggcgctggca
    73861 gggtgcgaca acaacgataa cgcgccaaca gcggtgaaaa aagatgcgcc ttctgaagtt
    73921 actaaagcgg cctcttcaga aaacgtgagt tcagcaaaac tttccgcgcc ggagcgacaa
    73981 aaactggccc aacagagtgc cggtaaggcg ctgacattgc tggatctctc tgaagttcaa
    74041 cttgatggcg cagccacgct ggtgctgacg ttctccattc ctctcgaccc ggatcaggat
    74101 ttctcacgcg ttatccatgt cgtcgataag aaaagcggca aagtggatgg tgcctgggag
    74161 ctgtcagata atcttaaaga gttgcgttta cgccacctcg aaccgaaacg tgatttgatc
    74221 gtcactattg gcaaggaggt caaagcactc aacaacgcaa ccttcagtaa agatgacgaa
    74281 aaaactataa ctacccgtga tatccaaccc agcgtcggtt ttgccagccg tggttcgttg
    74341 ttacctggta aagttattga agggctgccg gtaatggcgc tcaacgttaa caatgtcgat
    74401 gttaacttct tccgtgtgaa accagaatca ctgcccgctt tcattagcca atgggaatac
    74461 cgcaattcgc tggcgaactg gcagtcagac aaactgctgc agatggcgga tctggtctac
    74521 actggacggt ttgatctcaa tcctgcgcgt aacacccgtg aaaaattatt gctgccgctg
    74581 ggcgatatca aaccgcttca gcaggcaggc gtgtatctgg ctgtgatgaa tcaggctgga
    74641 cgttacgatt acagtaatcc cgcgacgctg tttacgttaa gtgatatcgg cgtttcagct
    74701 caccgttatc acaatcgtct ggatatcttt acccaaagtc tggaaaacgg cgcggcccag
    74761 caaggaatag aagtctcttt attaaatgag aaagggcaga ctctgactca ggcaaccagt
    74821 gatgctcagg ggcatgtgca gctggaaaat gataaaaatg cggcattact gctggcgcgt
    74881 aaagacggtc agacaacgct actcgattta aaactcccgg cgctggactt agcggaattt
    74941 aacattgctg gcgcgccggg ctatagcaaa cagtttttca tgtttggccc gcgcgatctt
    75001 tatcgcccgg gtgaaacggt catcctcaat ggtttgctgc gtgatgcaga cggtaaagca
    75061 ttgcccgatc aacccatcaa gttagacgtg attaaacccg acgggcaggt actcaggagc
    75121 gtcgttagtc agccggagaa tggcctctac cactttacct ggccactcga tagcaatgcg
    75181 gcaaccggta tgtggcatat tcgcgctaac acgggcgata accagtaccg gatgtgggat
    75241 ttccacgtcg aagattttat gccagagcgc atggcgctga atctgaccgg tgagaaaacc
    75301 ccgctaacgc cgaaagatga agtgaaattc tccgtggtgg ggtactacct gtatggtgcg
    75361 cctgctaatg gtaatatttt gcaagggcaa cttttcctgc gcccactgcg tgaagctgtg
    75421 tcagccttac ctggtttcga attcggcgag atagctgccg aaaatctttc ccgcacgctg
    75481 gatgaagttc agttgacgct ggatgataaa gggcgtggcg aagtttctac agaaagccag
    75541 tggaaggaaa cgcattcccc attacaggtt attttccagg gtagtttgct ggaatcgggc
    75601 ggtcgcccgg tgacgcgccg cgctgagcag gctatctggc ctgccgatgc attgccgggg
    75661 atccgtccgc agttcgcctc gaaatcggct tacgattatc gcactgacag cactgtgaaa
    75721 cagcccattg ttgatgaagg cagtaacgcc gcttttgaca tcgtttatag cgatgcgcaa
    75781 ggcgtaaaaa aagccgtgtc gggcttgcag gtgcgcctga ttcgcgaacg ccgcgattac
    75841 tactggaact ggtcagaaga tgaaggctgg cagtcacagt ttgatcaaaa agatctgatc
    75901 gaaaatgaac aaactctgga tctgaaagcg gacgaaaccg gcaaggtcag tttcccggta
    75961 gagtggggcg cttatcgtct ggaagtcaaa gcgccgaatg aagcggtcag tagtgtgcgt
    76021 ttctgggctg gctatagctg gcaggacaac agcgacggga gcggtgccgt gcgacccgac
    76081 cgtgtcacgc tgaaactgga taaagccagt tatcgccctg gcgataccat taagttgcat
    76141 attgctgcgc caacggcggg taaaggttat gcgatggtcg agtccagtga agggccgctg
    76201 tggtggcaag agattgatgt tccggctcaa gggctggatc tgacgattcc ggtcaataaa
    76261 acctggaatc gtcatgatct ttatttgagt acgctggtgg tgcgtcctgg cgataaatct
    76321 cgctccgcga cgccaaaacg cgcggttggt gtgttgcatc tgccgcttgg tgatgaaaac
    76381 cgtcgcctcg atctggcgct ggaaacacca gcaaaaatgc gtcccaatca accattaacc
    76441 gtgaaaatta aagccagcac taaaaatggc gagaagccta aacaggtgaa tgtgctggtg
    76501 tctgccgttg atagtggtgt gctgaatatt actggctacg ttacgccaga tccgtggcag
    76561 gcgttctttg gtcagaaacg ctatggcgca gacatttacg atatttacgg tcaggttatt
    76621 gaaggtcagg ggcgtctggc agctctgcgt ttcggtggcg atggtgatga gctgaaacgt
    76681 ggtggtaaac cgccggtcaa tcacgtcaat attgtcgcgc agcaggcgct gccggtaacg
    76741 ctcaacgaac agggcgaagg ctcggttgca ctgccgattg gcgattttaa cggtgaattg
    76801 cgcgtcatgg cgcaagcctg gacggcagat gacttcggta gcaacgaaag caaagtgata
    76861 gttgccgcac cggtgattgc tgaactgaac atgccgcgct ttatggcgag tggcgatacc
    76921 tcgcgtctga cgctggatat cactaatctt accgataaac cgcaaaaact gaacgttgcc
    76981 ctgaccgcca gtggtttgct tgaactggtc agcgattcac ccgcagccgt tgaattagcg
    77041 ccaggggtgc gtactacgct gtttatcccg gtgcgtgctc tgacggggtt tggcgatggt
    77101 gacattcagg ccaccattag cgggttagcg ttaccggggg aaaccgttgc cgatcagcat
    77161 aaacagtgga aaatcggcgt ccgtccggca ttcccggcac aaacggtcaa ttacggtacg
    77221 gcgttgcagc ctggtgagac atgggcgatt ccagctgatg gattgcaaaa cttctcgcct
    77281 gttacgctgg aagggcaatt gttgttgagc ggcaaaccac cgttgaatat tgcacgttat
    77341 atcaaagagt taaaagcgta tccgtacggt tgtctggagc aaaccgccag cggcctgttc
    77401 ccgtcacttt acaccaacgc agcccaactg caggcgttgg gcatcaaagg cgacagtgat
    77461 gagaagcgcc gtgcggcagt cgatatcggc atttctcgtt tactgcaaat gcaacgtgat
    77521 aacggtggct ttgcgctgtg ggataaaaac ggtgatgaag agtactggct gacggcttac
    77581 gtgatggatt tcctggtccg cgcaggtgag cagggttaca gcgtgccgac agacgccatt
    77641 aaccggggga atgagcgtct actgcgctat ttacaagatc cgggcatgat gtcgattccg
    77701 tatgcggata atctcaaagc cagtaaattc gccgtacagt cttacgctgc gctggtgctg
    77761 gcccgtcagc aaaaagctcc actgggtgcg ctgcgtgaaa tctgggagca tcgtgcagat
    77821 gccgcttctg gtttaccgct gctgcaactt ggcgttgcgc tgaaaaccat gggtgatgcg
    77881 acgcgtggtg aagaagcaat tgcgctggcg ctgaaaacgc cgcgtaatga tgagcggaaa
    77941 tggctgggtg attacggtag cccactgcgc gacaacgcgt taatgctctc cttgctggaa
    78001 gaaaataaac tgctacccga tgagcagaac actttgctga atacgctttc gcagcaggcg
    78061 tttggtgaac gctggctatc gacgcaggaa agtaacgcgt tgttcctggc tgcccgtacg
    78121 gttcaggatt taccgggtaa atggcaggcg caaacctctt tctcagctga gccgctgaca
    78181 ggcgagaaaa cgctaaacag caatctgaat agtgatcaac ttgccacctt gcaggtgacc
    78241 aacagtggcg atcagccgtt atggctgcgt gtggatgcca gcggttatcc gcaatccgca
    78301 cctttaccgg cgaacaatgt gctgcaaatc gagcgtcata ttcttggtac tgatggtaag
    78361 agcaaatcgc tggactcgtt acgtagcggc gatctggtgc tggtctggtt gcaggtaaaa
    78421 gccagtaaca gcgtgccgga tgcgttagtc gtggatctgc tgcctgcggg tctggaactg
    78481 gaaaaccaga atctggcgaa cggtagcgcc agcctggagc aaagtggtgg cgaagtgcaa
    78541 aacttactga accagatgca gcaggcgagc attaagcaca ttgagttccg tgacgatcgc
    78601 tttgtggcgg cggttgccgt tgatgaatac caaccggtaa cgctggtgta tctggcgcgg
    78661 gcggtgacgc cgggaacgta tcaggtaccg caaccgatgg tggaatcaat gtatgttccc
    78721 caatggcggg cgaccggcgc ggctgaagat ttgctgattg tcagaccgta aatgcctcgc
    78781 ttgttaacca aacgcggctg ctggataacg ctggcagctg cgccatttct cctttttctt
    78841 gcagcgtggg gagcagataa actctggcct ctaccgctgc atgaagtcaa tcccgcacga
    78901 gtggttgtgg cgcaggatgg gacgccgctc tggcgctttg ccgatgcgga aggcatctgg
    78961 cgttatccgg taacaatcga agatgtttct ccacgttacc ttgaagcgct gatcaattat
    79021 gaagatcgct ggttctggaa gcatccgggg gtgaatccat tctcggtggc gcgcgcagca
    79081 tggcaagatc tcacttcggg aagggttatt tccggtggca gcacgctcac tatgcaggtt
    79141 gctcgtctgc ttgatcctca ccccaaaaca tttggcggca aaattcgcca gctctggcgc
    79201 gcgttgcaac tggagtggca tctgtctaag cgtgaaattc tgaccttgta tcttaaccgc
    79261 gctccgtttg gcggtacgtt gcaggggatc ggtgcggcaa gttgggctta tctcggaaaa
    79321 tcgcctgcga atttaagcta ttccgaggcg gcaatgctgg cggtgttgcc gcaagcgccc
    79381 agccgactgc gcccggatcg ctggccggaa cgtgccgaag ccgcgcgtaa taaagtgctc
    79441 gaaaggatgg ccgtgcaagg tgtgtggtcc cgtgagcagg taaaagagtc aagggaagaa
    79501 cccatctggc tggcaccccg acaaatgccg caactggcac cgctgttttc gcgcatgatg
    79561 ctcggtaaaa gcaaaagcga caaaatcgtt actacgctgg atgccggtct tcaacgacgt
    79621 ctggaagaac tggcgcaaaa ctggaaagga cgattgccac cgcgcagctc actggcgatg
    79681 atcgtggttg atcataccga tatgcgtgtt cgcggctggg tgggatcggt tgatctcaac
    79741 gatgattcac gctttggtca tgttgatatg gtcaatgcga tccgatcgcc aggatcggtg
    79801 ctcaaaccgt ttgtttatgg tctggcgctg gatgaaggct tgatccaccc ggcatcgctg
    79861 ttgcaagacg tcccccgacg caccggtgat taccgacctg gcaactttga cagcggtttt
    79921 catgggccga tcagcatgag tgaggcgctg gtgcgatcgc tgaacttacc tgctgtgcag
    79981 gtgctggaag cctatggacc gaaacggttt gcggcaaagt tacgcaatgc tggattgccg
    80041 ttatatttgc ccaacggtgc tgcgccgaat ctttcgctca ttctcggcgg cgctggtgca
    80101 aaactggaaa atatggcggc agcgtatacc gcgtttgctc gccacggcaa ggcaggtaaa
    80161 ttgcgcttac agcctgatga tccgctgctt gaacggcctt taatgtcgtc gggggctgcg
    80221 tggatcattc gccggattat ggctgatgaa gcgcaaccct tgccggatgg tgccttgccg
    80281 cgcgtcgccc cactggcatg gaaaacgggc accagctatg gctatcgtga tgcctgggcg
    80341 attggggtta acgctcgcta tgtcattggg atctggactg gcagaccgga cggcacgccc
    80401 gttgttggtc agtttggctt tgccagcgcc gtaccattgt tgaatcaggt caataatatc
    80461 ttactgtcgc gcagtgcgaa tctgccggaa gacccacgtc ctgactctgt aagtcgtggc
    80521 gttatctgct ggccgggcgg acagtctttg ccggaaggtg acagtaactg tcgccgccgc
    80581 ctggcaacct ggctgctgga cgggagtcag ccgccaactc tattactgcc ggagcaggaa
    80641 ggcattaatg gcattcgttt ccccatctgg ctggatgaaa acggcaaacg tgttgccgct
    80701 gattgccctc aggcgcgaca agaaatgata aatgtctggc cgctaccgct ggaaccctgg
    80761 ctgcccgcat cagaacgtcg cgctgtgcgc ttgccaccgg cctcgacaat ttgcccgcca
    80821 tacggtcacg atgcacaact cccgctgcag ctaacaggtg tgcgcgatgg cgcgattatt
    80881 aaacgtttac cgggcgcagc ggaagcgact ttgccgttac aatcaagtgg aggggcaggt
    80941 gaacgctggt ggtttctgaa cggcgaaccg ttaactgaac gtgggcgcaa cgtgaccctg
    81001 catttgacgg ataaaggcga ttatcaattg ctggtgatgg atgaggtggg gcaaatagcg
    81061 acagtgaaat ttgtcatgca atagtctgtt ttgcccctga ttgttgctta aactgggttt
    81121 attttaaaaa aatgttacct tcatcaatag tcaacggctc tgttgctcat tataatccgc
    81181 gccatctcgt acgctggtac agacaacaac agaacaattt acagaggtaa aaatggctat
    81241 tgaacgtact ttttccatca tcaaaccgaa cgcggtagca aaaaacgtga ttggtagtat
    81301 ctttgcgcgc tttgaagctg cagggttcaa aattgtcggc accaaaatgc tgcacctgac
    81361 cgttgaacag gctcgtggct tttatgctga acacgatgga aaaccgttct ttgatggtct
    81421 ggttgaattc atgacttctg gcccgatcgt tgtttccgtg ctggaaggtg aaaatgctgt
    81481 tcagcgtcac cgcgatctgc tgggcgcgac caatccggca aacgcactgg ccggtactct
    81541 gcgtgctgat tacgctgaca gcctgaccga aaatggtacc cacggttctg attccgtcga
    81601 atctgccgct cgcgaaatcg cttatttctt cggcgaaggc gaagtgtgcc cgcgcacccg
    81661 ttaataattt cgtaaatgct acgtgcaaac gtggcatccg tgcgccagaa tttgtacaat
    81721 gcagcgcccc cggacgagca gccgctcacc ggggcgtttc ttttttcaac cctccagggg
    81781 ccataacgtg taataacgag gccggaatag catatgtctg aacaattagt cacacctgaa
    81841 aacgtcacca ctaaagatgg aaaaatcaac ctgctggatc tcaaccgtca gcagatgcgg
    81901 gagtttttta aagatttagg tgaaaaaccc ttccgcgccg atcaggtgat gaagtggatg
    81961 tatcactatt gctgcgacaa ctttgatgag atgaccgaca tcaacaaagt gttgcgcggc
    82021 aaactgaaag aggtggcgga aatccgtgca ccggaagtgg ttgaagaaca gcgttcatct
    82081 gacggcacca ttaaatgggc aattgccgtt ggcgatcagc gcgtcgaaac ggtgtatatc
    82141 ccggaagacg accgtgccac gctctgcgtc tcttcgcagg tggggtgtgc gctggagtgt
    82201 aaattctgtt ccaccgccca gcagggcttt aaccgcaacc tgcgggtatc ggaaattatc
    82261 ggtcaggtgt ggcgtgcggc gaaaattgtc ggcgcagcaa aagtcaccgg tcagcgccca
    82321 atcactaacg tcgtgatgat gggtatgggc gagccgctgc tcaacctgaa caacgtcgtt
    82381 ccggcgatgg aaatcatgct tgatgatttc ggttttggcc tgtcaaaacg tcgcgtgacg
    82441 ctttccactt ccggtgtagt tccggcgctg gataaactgg gcgatatgat cgacgttgca
    82501 ctggcaattt ccctgcacgc gccgaacgac gaaattcgtg acgaaattgt gccgatcaac
    82561 aaaaagtaca atatcgaaac gttccttgct gcggtacgcc gttatctgga gaaatccaac
    82621 gccaatcagg gccgagtcac tattgaatac gtgatgcttg accacgttaa cgacggcact
    82681 gaacacgcgc accaactggc ggagctactg aaagatacgc cgtgtaagat caacctgatc
    82741 ccgtggaacc cgttccctgg cgcgccgtat ggacgcagct caaacagtcg tatcgaccgt
    82801 ttctctaaag tgctgatgag ctacggtttc accactattg tgcgtaaaac tcgtggtgat
    82861 gatatcgatg ctgcctgtgg tcagttggcg ggcgatgtta tcgaccgtac gaaacgtacc
    82921 ctgcgtaaac ggatgcaggg tgaagccatc gatattaaag cggtctgata gccattacgc
    82981 cacggttact ttatgtaccg tggcgtaatc ttttatgaat gaagtattaa gttgcaattg
    83041 tctggtcaat attaacggtg cgtttttgct gactttaagg cagtatgtaa cgatgcaaca
    83101 gtaagttagc cttagtgaat gtgggctttg tcacgagcac acagacggtc ttatactgta
    83161 tgataacggt taacttaacg gatgtttcgc ggtgtgggtg agcatgatgg ttcaccggca
    83221 tctcaattct catttaaacg tacctgcagc gaatgaatac tgaagccacg cacgaccaaa
    83281 atgaagcact tactaccggc gctcgcctgc gtaatgctcg cgaacaacta ggacttagtc
    83341 aacaggccgt tgccgagcga ctttgcctga aggtttccac ggtacgcgac attgaagaag
    83401 ataaggcacc cgccgatctt gcttcaacat tcctgcgcgg atatatccgc tcttatgcgc
    83461 gtctggtaca tattccagaa gaagaactgc tgccagggct ggaaaagcag gctccactac
    83521 gggctgcaaa agttgcgccg atgcagagtt tttccctcgg taaacgccgc aaaaaacgtg
    83581 acggctggct gatgaccttc acctggctgg tgttgtttgt ggttattggc ctgagcggtg
    83641 cctggtggtg gcaagaccac aaagctcagc aggaagagat caccactatg gccgatcaat
    83701 cttctgcgga actgaataat aatcaaagcc agagtgtacc gttagatacg tcgacaacca
    83761 cagatcaggc tatggcgacc acgccgacat caccggtgga taccaccgca actaacacgc
    83821 aaacacctgc cgcgacgacg gctccatcgc caaccgtcga ttcacaacag aatgcggttg
    83881 ttccaccttc gcaggcaaat gttgataccg ctgcgactcc ggcaccagcg gcaacaacaa
    83941 caccagatgg cgctgcgccg ttgccaaccg atcaggctgg cgtgactacg ccggcggttg
    84001 acccgaatgc gctggtgatg aactttactg ccgattgctg gctggaagtc accgatgcta
    84061 ccggtaaaaa actgtttagc ggtatgcagc gtaaagacgg taatttgaac ttaaccggcc
    84121 aggcaccgta caaactgaaa attggtgcgc cagccgcagt acagatccag tatcaaggga
    84181 aacctgtcga tctgagtcgt tttatcagaa ctaaccaggt tgcgcgtctg accctcaatg
    84241 ccgaacaatc accggcgcag taacagacgg gtaacgcggg agatttttca tgcataacca
    84301 ggctccaatt caacgtagaa aatcaacacg tatttacgtt gggaatgtgc cgattggcga
    84361 tggtgctccc atcgccgtac agtccatgac caatacgcgt acgacagacg tcgaagcaac
    84421 ggtcaatcaa atcaaggcgc tggaacgtgt tggcgctgat atcgtccgtg tctccgtacc
    84481 gacgatggac gcggcagaag cgttcaaact catcaaacag caggttaacg tgccgctggt
    84541 ggctgacatc catttcgact atcgcattgc gctgaaagta gcggaatacg gcgtcgattg
    84601 tctgcgtatt aaccctggca atatcggtaa tgaagagcgt attcgcatgg tggttgactg
    84661 tgcgcgcgat aaaaacattc cgatccgtat tggcgttaac gccggatcgc tggaaaaaga
    84721 tctgcaagaa aagtatggcg aaccgacgcc gcaggcgttg ctggaatccg ccatgcgtca
    84781 tgttgatcat ctcgatcgcc tgaacttcga tcagttcaaa gtcagcgtga aagcgtctga
    84841 cgtcttcctc gctgttgagt cttatcgttt gctggcaaaa cagatcgatc agccgctgca
    84901 tctggggatc accgaagcgg gtggtgcgcg cagcggggcg gttaaatccg ccattggttt
    84961 aggtctgctg ctgtctgaag gcatcggcga cacgctgcgc gtatcgctgg cggccgatcc
    85021 ggtcgaagag atcaaagtcg gtttcgatat tttgaaatcg ctgcgtatcc gttcgcgcgg
    85081 gatcaacttc atcgcctgtc caacctgttc gcgtcaggag tttgatgtta tcggtacggt
    85141 taacgcgctg gagcaacgcc tggaagatat catcactccg atggacgttt cgattatcgg
    85201 ctgcgtggtg aatggcccag gtgaggcgct ggtttctaca ctcggcgtca ccggcggcaa
    85261 caagaaaagc ggcctctatg aagatggcgt gcgcaaagac cgtctggaca acaacgatat
    85321 gatcgaccag ctggaagcgc gcattcgtgc gaaagccagt cagctggacg aagcgcgtcg
    85381 aattgacgtt cagcaggttg aaaaataata acgtgatggg aagcgcctcg cttcccgtgt
    85441 atgattgaac ccgcatggct cccgaaacat tgagggaagc gttgagggtt catttttata
    85501 ttcagaaaga gaataaacgt ggcaaaaaac attcaagcca ttcgcggcat gaacgattac
    85561 ctgcctggcg aaacggccat ctggcagcgc attgaaggca cactgaaaaa cgtgctcggc
    85621 agctacggtt acagtgaaat ccgcttgccg attgtagagc agaccccgct attcaaacgt
    85681 gcgattggtg aagtcaccga cgtggttgaa aaagagatgt acacctttga ggatcgcaat
    85741 ggcgacagcc tgactctgcg ccctgaaggg acggcgggct gtgtacgcgc cggcatcgag
    85801 catggtcttc tgtacaatca ggaacagcgt ctgtggtata tcgggcctat gttccgtcac
    85861 gagcgtccgc agaaagggcg ttatcgtcag ttccatcagt tgggctgcga agttttcggt
    85921 ctgcaaggtc cggatatcga cgccgaactg attatgctca ctgcccgctg gtggcgcgcg
    85981 ctgggtattt ccgagcacgt aactcttgag ctgaactcta tcggttcgct ggaagcacgc
    86041 gccaattacc gcgatgcgct ggtggcattc cttgagcagc ataaagaaaa gctggacgaa
    86101 gactgcaaac gccgcatgta cactaacccg ctgcgcgtgc tggattcaaa aaatccggaa
    86161 gtgcaggcgc ttctcaacga cgctccggca ttaggcgatt atctggacga ggaatctcgt
    86221 gagcattttg ccggtctgtg caaactgctt gagagcgcgg ggatcgctta caccgtcaac
    86281 cagcgtctgg tgcgtggtct ggattactat aaccgtaccg ttttcgagtg ggtgactaac
    86341 agtctcggct cccagggcac cgtgtgtgca ggcggtcgtt atgacggtct ggtggaacaa
    86401 ctgggcggtc gtgcaacacc ggctgtcggt tttgcgatgg gcctcgaacg tcttgtattg
    86461 ttagtacagg ccgttaatcc ggaatttaaa gccgatcctg ttgtcgatat atacctggtg
    86521 gcttcaggtg ctgatacaca atctgcggct atggcattag ctgagcgtct gcgtgatgaa
    86581 ttaccgggcg tgaaattgat gaccaaccac ggcggcggca actttaagaa acagtttgcc
    86641 cgtgctgata aatggggtgc ccgcgttgct gtggtgctgg gtgagtctga agtggctaac
    86701 ggcacagcag tagtgaagga tttgcgctct ggtgagcaaa cggcagttgc gcaggatagc
    86761 gtagccgcgc atttgcgcac gttactgggt taaggaagga gaaggacagc gtggaaattt
    86821 acgagaacga aaacgaccag gttgaagcgg ttaaacgctt ttttgctgaa aatggcaaag
    86881 cactggctgt tggggtgatt ttgggcgttg gcgcactgat tggctggcgc tactggaata
    86941 gccatcaggt tgattctgca cgctccgctt ctcttgccta tcaaaatgcg gttaccgcag
    87001 tgagcgaagg caaaccggat agcatcccgg cggcggaaaa atttgctgct gaaaataaaa
    87061 atacctatgg tgcgctggct tctttggaac ttgcgcagca atttgttgac aaaaatgaac
    87121 tagagaaagc tgccacccag ttacaacagg gattggcgga cacgagcgat gaaaatctca
    87181 aagccgtgat aaatctgcgt cttgcccgcg ttcaggtaca gctcaagcag gctgatgccg
    87241 cgctgaagac cctcgatacc atcaaaggtg aagggtgggc tgccattgtt gccgacctgc
    87301 gtggcgaagc attgctgagc aaaggtgata agcaaggtgc gcgtagtgca tgggaagcag
    87361 gcgtgaaaag cgatgttacc ccggcactga gcgaaatgat gcagatgaaa attaataatt
    87421 tgtccatctg agagggaccc gatgcaattg cgtaaattac tgctgccagg actgctttcc
    87481 gttacccttt taagcggctg ttcgctgttt aacagcgaag aagatgtggt aaagatgtcc
    87541 ccattgccaa ccgttgaaaa ccagtttacg ccgactactg cgtggagcac ttccgttggt
    87601 agcggcattg gcaacttcta ttccaatctt catccggcac tggcggacaa cgttgtctat
    87661 gcagcggacc gcgctggttt agtaaaagcg ctgaatgcgg atgatggcaa agaaatctgg
    87721 tctgtcagcc tggccgagaa agatggctgg ttctctaaag agcctgcatt actttctggc
    87781 ggtgtgaccg tgtctggtgg gcatgtctac attggcagcg aaaaggcgca ggtttacgcg
    87841 ctgaatacca gcgatggtac tgtggcatgg caaactaaag tcgcgggtga agcactttcg
    87901 cgtccggtgg tcagcgacgg tctggtgtta atccacacca gtaacggtca gttacaagcg
    87961 ctgaacgaag ctgacggcgc tgtcaaatgg acagttaacc tcgatatgcc ttcgctctct
    88021 ttgcgtggcg agtctgcgcc ggcaacggct tttggtgcgg ccgtcgtggg tggcgataat
    88081 ggtcgcgtca gcgcagtgct gatggaacag ggccagatga tttggcagca gcgtatttcc
    88141 caggcgaccg gttctaccga aattgaccgt ctgagcgatg ttgacacgac acccgtcgtt
    88201 gttaacggcg ttgttttcgc gctggcctat aatggtaacc tgacggcgct tgatctgcgc
    88261 agtggtcaga ttatgtggaa acgcgaactg ggttcggtga atgatttcat cgtcgacggc
    88321 aatcgcatct atctggtcga tcaaaatgac cgggtgatgg cgttgaccat tgatggcggc
    88381 gttacgctgt ggacacaaag cgatctgctg catcgcctgc tgacttctcc ggtgctgtat
    88441 aatggcaacc tggtggtagg tgacagtgaa ggttatctgc actggattaa cgtcgaagat
    88501 ggtcgtttcg ttgcccagca aaaagttgat agttccggtt tccagactga accggttgcc
    88561 gctgacggca aactgctgat ccaggcaaaa gacggaaccg tgtactctat tacacgttaa
    88621 tcgtctctgt cgttcacttt gaaaacggct cctggacagg ggccgttttc ctgtttttaa
    88681 caacgacacg aatatagcgt gcgttgtctg atgatttata aaaatgaggc tttaaacatg
    88741 gtacctgtgg tcgcgcttgt cgggcgccct aacgtaggaa aatccacgtt atttaaccgt
    88801 ctaactcgca cccgagatgc gctggttgcg gatttcccgg gtctgactcg tgaccgtaag
    88861 tacggtcgtg cggaaattga aggccgtgag tttatctgca ttgataccgg cgggattgat
    88921 ggcacagaag acggtgtaga aacccgcatg gcggaacagt cgctgctggc gattgaagaa
    88981 gcggacgtcg tactgtttat ggtggatgcg cgcgcgggcc tgatgccggc ggatgaagcg
    89041 attgctaaac atctgcgctc ccgtgaaaaa ccgaccttcc tggtggcaaa caaaactgac
    89101 ggtctggatc ccgatcaggc agtggttgat ttctactcgc ttggtttagg tgaaatctac
    89161 ccgatcgccg cgtctcacgg tcgtggcgta ttaagtctgc tggagcacgt gctgctgccg
    89221 tggatggaag atctcgcacc gcaagaagaa gtcgacgaag acgccgaata ctgggcgcaa
    89281 tttgaagcgg aagagaacgg cgaagaagaa gaggaagacg acttcgaccc gcaaagtctg
    89341 ccgatcaaac tggcgattgt gggtcgtccg aacgtcggta agtctacgct cactaaccgt
    89401 attctcggtg aagaacgcgt tgttgtttac gacatgcctg gcacgacgcg tgacagtatc
    89461 tacattccaa tggaacgcga cggacgtgag tatgtgctca ttgacaccgc tggcgtacgt
    89521 aaacgcggca aaatcaccga tgcggtagag aagttctcgg taatcaaaac gttgcaggcc
    89581 attgaagatg ccaacgtggt gatgttggtg attgatgcgc gtgaaggtat ttccgatcag
    89641 gatctctcct tgctgggctt tattctcaat agtgggcgct cacttgtgat tgtagtgaac
    89701 aagtgggacg gcctgagcca ggaagtgaaa gagcaggtga aagagacgct ggacttccgt
    89761 ctgggcttta tcgattttgc tcgtgtgcac tttatctctg ccttgcacgg cagtggtgtt
    89821 ggtaacttgt ttgaatcagt acgtgaagcg tatgacagct ccacccgtcg tgtggggacc
    89881 tctatgctga cgcgcatcat gacgatggcg gttgaagatc accaaccgcc gctggtacgc
    89941 ggtcgtcgag tgaagctgaa atatgcccac gccgggggtt ataacccgcc gattgtggtg
    90001 attcacggta atcaggtgaa agacctgcct gattcctaca agcgttacct gatgaactac
    90061 ttccgcaaat cgctggacgt aatgggatcg ccgattcgta ttcagttcaa agaaggggaa
    90121 aacccgtatg cgaacaagcg taataccctg acgccgactc agatgcgcaa gcgtaagcgt
    90181 ctgatgaagc acatcaagaa aagtaagtaa tcacttatct ggtttccctt tccacacgga
    90241 gagggaagcc tatgaaatgt gaggagcatt tatggaactc aattgcccaa tctgcaaaac
    90301 ccctctcgaa cgcaatggcg agactgctca ctgtgcaact tgcgacaaag actttaccgt
    90361 ccaggcactt tgccctgagt gtcatcaggc gttacaagtg ttaaaagctt gtggtgctgt
    90421 ggattatttc tgccaacatg ggcacggttt aatatctaaa aaacgcgttg aatttattat
    90481 tgcttaatat catgtgaatg tattgtttta tcatttatat ttaatgcatg aatggtaaaa
    90541 caatttgtta ttagtggaat aactaatgca attgagtgag atcactaatt taaataatta
    90601 agaatatatt tattctttat ggcatgcctt tctgaataat cagggataca atattaaagc
    90661 ttatttttga ctttatcatt gtcacaggaa aagtgcatgc tgcgatggac acgctgtatt
    90721 atgctaacat ttatctctgg ggctgctttt gcggctccag agataaatgt tgagcataaa
    90781 gaatcattac ctgatttagg tagtcaggcc gcacaacaag aagaacaaac caacaagggg
    90841 aaatcgctaa aagagcgtgg tgccgattac gtcattaact ccgctacgca agggtttgaa
    90901 aacctgacac ccgaggcgct ggagtcccag gccagaagct atctgcaaag tcaaattacc
    90961 tctacgacac aatcttatat tgaggataca ctctccccct acggtaaggt tcgaacgaat
    91021 ctttctcttg gccagggcgg tgatctggat ggcagttcca tcgattattt tgttccctgg
    91081 tatgataatc aaaccactgt ttatttcagc caactttctg cacaacgaaa agaagatcgt
    91141 acgatcggga atattgggct tggtgtaaga cataattttg ataaatggtt gttgggtgga
    91201 aatatatttt atgattatga ttttacccgt gggcatcgcc gtttaggttt aggcgccgaa
    91261 gcgtggactg attatttaaa attctctggc aactattatc acccgctttc tgactggaaa
    91321 gactccgaag attttgattt ttatgaggag cgtcctgcgc gcggctggga tattcgcgcc
    91381 gaagcctggc ttcccgctta tccgcagctt ggtggtaaaa ttgttttcga acagtattac
    91441 ggtaatgaag tcgcgctttt tggcactgat aatctggaga aagatccctt cgctgtcacg
    91501 ctgggtgtga aataccagcc cgttccgctc attgctgtcg gtacagattt caaagctggc
    91561 actggcgata ataccgatct ttctgttaac gcaacgctta attatcagtt tggcgtcccg
    91621 ctcaaagacc agcttgatcc tgacaaagtg agcgcggctc actcgcttat gggcagccgt
    91681 catgactttg ttgaacgtaa caactttatt gttctggaat acaaagaaaa agatcccctc
    91741 gacgtcactt tgtggctgaa agccgacgcc acgaatgaac atcccgagtg cgtgattaaa
    91801 gatacgcctg aagaagctat cgggctggaa aaatgtaaat ggaccattaa cgcgctcatt
    91861 aaccatcact acaaaatcgt cgctgcctcc tggcaggcga aaaacaatgc tgcacgtacg
    91921 ctggtgatgc cggttatcaa agaaaacacg cttaccgaag gtaacaacaa ccactggaat
    91981 ctggtgctgc ctgcctggca gtacagttct gataaagccg aacaagaaaa actcaatacc
    92041 tggcgggttc gtctggcgct ggaagatgaa aaaggtaatc gacagaattc cggcgtggtg
    92101 gaaatcaccg ttcagcagga tcgcaaaatt gagctcatcg ttaacaacat cgccgatgta
    92161 ccagacgaga acaatcacag tcatgaagcc agcgcacagg ccgatggtgt agatggtgtg
    92221 gtgatggatc tcgatattac tgatagcttt ggcgacaaca ctgaccgcaa cggtaatgtc
    92281 ttgccgcagg ataatctcaa cccgcagttg tttgacgcca acgataaaaa agtgacgctg
    92341 acgaataaac cctgcactac cgagactccc tgtgtcttta tcgccaaaca agataaagaa
    92401 aaggggaccg ttacgctctc cagtacattg cctggcacct tccgttggaa ggcgaaagcc
    92461 gctccctatg atgacagtaa ctatgttgac gtaacgttcc tgggttctga catcggcggg
    92521 ctgaatgcct ttatctatcg tgttggtgcg gctaagcccg tgaatcttat cggcaataaa
    92581 gagccgttgc ctctcaatag cagctatcgc tttgtgttgt ggcgtgacgc taacaaagac
    92641 ggcgtgttcc agctatcaga gaaactcact gaagaggaga tgaaacagta tgactatcag
    92701 tgggaattca cgggacatag cgtgaatggc aataccggtg cgcaagccaa taccactaac
    92761 gccgatatag agatcccggc aacgaacaag gacgcggcaa cgaagtttag tgcccaggta
    92821 accgatggcg tgcagggata cggtttgcag gtcaattaca gcaagaaata ggatcagcgc
    92881 catggctgat cgggccaccg ctgaatgtta accaaggaga gtgtttatga aacctcatat
    92941 gaaacgtggc ctgacaagag tcgcgctggc actgatgctg gctggatact gtgccgtgcc
    93001 agccgctatg gcggaagatg ccgcctgggt agccagtggg acgaccgctg aattcgaagg
    93061 gaccataccc tggctttatc gcgagggtgg gaatgccacg attaactcgg atgatgcgga
    93121 tcacatcaaa gtaacgtctg atggtaaagg tactcgtcct tcaggtagcg agacggataa
    93181 acgcctttac tcaggagata ccatcacgtt ggggtgggat atcggcgata ccgaagggga
    93241 tatcgacgat ggtccagacg gtattgatgc gaaaacgaca gccactatca aatggtacag
    93301 ttacagcgat aatgcgggtg gcggtaaaac ggagctgatc gcagcggcag gcaagacgag
    93361 ttataaactc actgatgacg aacgtgggcg ttatatcggt gttgaaatcc agcccatcac
    93421 ccagaccgat aatcctttcc agggaacatc gctgactctg ctggatattt caacggccag
    93481 cggtggcggc agcgatacgg ataatgttga tcctggcccg gttgtgaacc agaacctgaa
    93541 agttgccatc ttcgagaaag gcaccagtac caaccttatc ggtggtaata cagccattgc
    93601 gcttaacaaa acgtatgtgg ccaaactgta ctcggatgaa aaccagaatg gtaagtacga
    93661 tgcgggtacg gatgtggacg ttaccgctaa ctacgacttt gcgtgggtct ttaacggtaa
    93721 cagtaaacaa cttgcggcgg cgggcggtat tgccaacgcc agcttcgata acaatgacat
    93781 tgttattccg caaactaacg aacaagcaag aaccagcctt aacggtagtg accgtaatgg
    93841 taagaccggc cttgcaatcc cggcaaacgg cgacggcgtt cagggctata cgctgtctat
    93901 catttacaaa caccactaat gcgcacaaca gcattcccgt atgggaatgc tgttttccgc
    93961 ctgttttgct tagcgacgcg ttaagcaaaa cgggttgacg ttttgtttat catgctggag
    94021 ttttctacat gtcggtatgt ctgaaaccag gaaaaatcat tgtgcttctg ggcatgttgg
    94081 cagcctttat gctgtctgac tttgcacggg caggagtgga atggcagaca tatcctggtt
    94141 ctacaggcga gtttaacggt acagttccta ttgccgatag cgctagcgta cccgtttatc
    94201 agggaagcgt tcagcttgat cctgctgcat ctcatgatgt ggcgttttct gctaaaccga
    94261 atgaatttag cgttgacgat gacgctgcta acctgatagt cgctaatcct caggacagtg
    94321 aaggcgacca gttttccaca ccacctgcgc tgcgctggga aaaccagacg ccgccgaccg
    94381 tcagtctggt gtgggcggat gccgccacgc cggatacgcc gctcaacccg cagcccatcg
    94441 ccaaccgcag cttttgcgcg caaggtctgg ccgggcgttc gctggtggcc tggccgcaga
    94501 tagatacaca acaatccatt ccactgcttt acctgctgac ctcgaccggt tatccctatg
    94561 aggggacggt ggcgctggct gaccagaaag tgacgctgaa catcgcgccc gcacagggcg
    94621 atttaatttc ggtgagcgcc agtggttata acgaaacgat cgcggcggca aaaaccaccg
    94681 ttggtggcac tatcacgctg accgtcacca ccaaagattg tcagggcaac gtcgcgggta
    94741 atattccgtt tattatcaaa cgtaaagatg cccaaaaccg tcagggcgcg gtgaataata
    94801 ccgcgccggt ggtgctgggg agtaccgagt taacgacgac ggcaaccgag tatcgtggca
    94861 catcggatgc caacggtacg gcaaccatca cggtgaccca acctaacggc cccggcgtca
    94921 aaacgccgct ggtggcgagt atttccggca ttgcgcaaac cagcgaaacg gcggtgattt
    94981 ttaccgtact taccagcccg gacgtggcgc aggccacgat gtggggccat atggcggaaa
    95041 cggttgaggc acacggctac acgttcagca ggccaaaact ggcggcggaa gtcagcaatg
    95101 aaaatgccac ggtcgtcgat cacaacgaaa cctggtccac tttcacctgg agcggggcag
    95161 acagccattg caccgtgctg ccgggcatgc gccatttcgg cgcactggcg acggtgattc
    95221 cctccacggt acagactgtc cttggctggc cgatgcagga tgattattac tggacatcgc
    95281 tggcgggcac taccgggcag caccatgcag cggatgtctc taaccgtgct gaagcgcaaa
    95341 agccggatag caccacgttt ctggtaagct gcgtggacaa acccgcgcct gacgtcgaac
    95401 cgaaaatcgt ccttacgcca gaaaactatg atgatacggc acaggcgatg aaagcgaagg
    95461 tgggtgagga tgccacgatg cgtctgacga tcaccgacaa taaaaacaac gatcaaccgc
    95521 tggcgtatta ctacttctcg ctgcatctgg atgacggcgt taaccgcaaa aatcaaaccg
    95581 atcctgcctg ggaaacccat ccggtacaga ttgctggtgg ctcgaattta caacaggttg
    95641 atgctcacac ctatgaaggc ataactgatg tcaacggtca ggcttcgcta accctgagcc
    95701 agcccggcgg cgcgggcgtt aaaactcaca tcacggcgag aatgcgcagc gattttacgg
    95761 ccacagatgc caaagacgtg atttttaccg tgatcactag cccggacagc gacaaagcgc
    95821 ggatgtgggg ccatatgcgc ggcattattg agtccggcag tctgtataaa cgcccattac
    95881 tggcggatga aaccgagcat gaactgggat cggtgcggga aaataacgaa gactgggcgc
    95941 tgtacgatca aaacaccagt atgcaggcgg aatgcggggt gggtcatata ccgcgtcaga
    96001 gctcactgga aagcctgttt tcagcccatc ccggtaacgc gattggcact gagtatggct
    96061 ggcctaccgc acaacagagc tacctaagcg cggtggagca agaaacgcat tcatcggtga
    96121 atctggcgaa cgggagcgtc gacagctact ccggctttaa gcagaattac ctctcctgct
    96181 cgggcaatga gatggtggcg aatgtcgaag tcagcaccga tcatgatgtc accgttggca
    96241 gcaaggcgca ggccaaagtg ggtgacacca tcgtaatgac cgtgcgtacg gttaacgggt
    96301 tgaataacac gccggtgccg tttaccgcat tcaccattac caaaggcatg gggtataacc
    96361 ggttggggca ggtgagcggg tttgatgacc cgagcagcgg cgcaatcacg atgaatgaca
    96421 cacaatacgg cacatcccag ccatcgatgg tttatgcggg aacgaccgat gcccagggcg
    96481 tggcgacggt cgagattaaa caaccgcagg gcgtcgggct aagaacggcg ctgagcgtaa
    96541 cgccggtaaa ttcctacctg ccgaataccg ttaactacaa cgttattttt accaccccaa
    96601 ccagcccgga cgtttccggt gcgcaaatgt ggggccatat ggatgaaacg ataactgtcg
    96661 attcatcaac ctttacccgg cctaagctgg cggcggaaat cgccagcccg gacggaaccc
    96721 tgaccgaaaa taacgaaatc tgggcgcgcg tgagccaggc caatacgtcc agtaccagca
    96781 aaggcggctg cgctaccaat atgttgccgc gtcgctccca gctaagcgcg ctctatagcg
    96841 ccaacagtgg taatgcagtg caaacgacgc acggctggcc aacgcagcgt cagccctact
    96901 ggagcagctc tccggcggat gtgacgccgc actttttcac gatagcgctg aacgatggcg
    96961 cacaagctat cggcggcaat acgccggttt acgtcagttg cctgacgacg gcgaacaagc
    97021 ctgccagcag cattacgctg gaggtggttg ataaagcgca atggaatgcc gggaataacg
    97081 cggcaacgct gaaaaaaggc gaaacgctac aggttaaggt gacggtaaaa gatgcacagg
    97141 gcaacgcgtt agcggatatg ccatttaccc tcagtcgcgg tgatggctat acccgtagcg
    97201 gcgaaaaaca tattgccggt agcggcgatg cgctggtggc gccggtggtg gtcaatggcg
    97261 ggctggccga tgaaacaacg ttgaatgaca ccgcaacggt gtataccgcc atgaccggca
    97321 gtgacggcag caaaattctt aatattaccc gtccggatac ccacggcacc aaaacggcgc
    97381 tgacggcaac gctttactcc gatgcgacga aaaaagacag cctggacacg atctttacgg
    97441 tggttaccag cccggatagc agccaggcga aaatgtgggg gcatatgccg gaaacggtga
    97501 cggctgagga cggtacggtc tttaaacgcc cgcggttact gaaggaactg agcagtcaga
    97561 ctgggcgaac atcaacgctt gaagacaacg aaaactgggc gttgtttaac attaattatg
    97621 cgagctcttc cacgacgtat agtggctgtg gaaccaacta tattccgact caggccggtc
    97681 tgacgtcact gtttgctaat aatgcgggca acaccatgaa aaccgtgcag ggctggccgg
    97741 tggcaacgcg ctatttgtcc aacacgtccg acaatggcag catggagcag cgtaactaca
    97801 aggcggtcga tctcagcaat ggcacgagtg cggcagtgtc atcaacggcg ctgcaactgc
    97861 tgacctgtca gactacaccg gtaaccacgg tgagccaaat cctgctggaa gcggcagatc
    97921 cggcgacgct ggataccacc tataacgtgg taaaagcgaa aaaaggcgaa gaatccgtgg
    97981 tgcgcgtcac caccaaagat gcacaaggca acctggtggg caatacggca tttatcctga
    98041 cgcgtgccaa cagcgtgagt cgggctaatg catcagcgac gatgagcgtg ggctcgttga
    98101 cggtgacgga tgcctggggc aatacgcgaa ataatttcca gtcgacaagt gaaaccattt
    98161 acggcgtgac cggtgccgac gggtcaacga cattgaccct gaaacaggat aacagtaccg
    98221 ggttaagaac cgatctcacg gcaaaactgg atacgtccag cagcgtcaag gcaacgctac
    98281 cggtggtctt taccgtcgtg accagcccgg attcgccaaa agcgaatttt tggggacata
    98341 tggccgaaac ggtggcggcc tccgatggtt cagtctataa acgcccactg ttgctggcag
    98401 agctggccaa cactggcggg cgacaaatca gttcagagaa cggggaaagc tgggtacgat
    98461 tcacctggaa tcagtcgaca gatccttctg taagcggctg cggcgttgcg tatatgccaa
    98521 cgttggcagg cctgcaagcg ttgtatgacg ctaatagtgg taatgcaatg agtacggtac
    98581 agggatggcc ggtaaaagcg acctatctca ccaatacccc aagtgacacg caaacgggga
    98641 gccgttacta caatgtggtg caactggatt ctggcgcagc ctcgcaaatc acgacgaaca
    98701 cgggtgtact gcaaacctgc cgtacaacgc cgttgacggc tgccagccag attacgctgg
    98761 aggccgcgga tcctgcgcaa tttgtcagta ttgacagcac gcttagcgct gtcaaagtgc
    98821 agaaaggcga tagcgtgccg atccgcattt cgactaaaga tgcgcagggc aatttcgtcg
    98881 gcaatacgcc gtttgccctg aaacacgcga actcgatcaa tcgtcaaaat gtgtcgtcat
    98941 cgcagaaagt gtcggtcacg acggaggtgg gtacgacggt ggataccagt gcaacaacca
    99001 ccctgtatgg cgtaaccggg ccagacggaa ccaccacgat gacgctccga caggatgcgt
    99061 ccaccgggtt aagaaccgac ttttatgccc tgttgaacga taccggcgtg tcgtcggaca
    99121 ccttgccggt gatctttacc gtcatcacca gcccggatac gccgctggcg gccaactggg
    99181 gccatatggc ggaaaccttt accagtagcg aaggcgtcac cttcaagcgg ccttccctca
    99241 aagctgaact ctctggcggt acggccataa cggtcaataa tgaagtctgg tcgcgcctga
    99301 cagcggcgga gaaagtggat gccagcaagg ccgggtgtga tgagacgtat caaccgctgg
    99361 tgaatgacat gcaggggttg tatgcggatt accctaacgg ccagttagga tcggtgctcg
    99421 gcttgccgac gtctgccggg tattggtggg cctacgacat gatgatggtt tctggcaact
    99481 ggactaatca ggcattttca cctgttaatg gtcagttgat gcaggcatcg tccagctata
    99541 cggcgatcgt gatgtgtctg gtagaaccac atacggaagc agccacaata gagcttactt
    99601 caacggcgca ggacgcagca aaatcggcca gtaatggtgg acgaccgagc gccgtagcga
    99661 agaaaggcga gacgattccg ttgacggtga ccgtgcgtga tagcgccggg aacccgatgc
    99721 catatgctga gtttaccctc acgcgtgaaa cgacgctgga tcgctcgaaa gcaaccgtta
    99781 acacgagtgc ggacgacctt accgtaacgg cattggtacc cgcgaataca aatagtgtgt
    99841 tggcagcaag tggagcaaaa ctgatcggca cgacgggcag cgatggcaaa gcgacctttg
    99901 aggtgagtca gaatgcgacg accgggctgg cgacgccgtt aaccgtgacg ctggcgcgtg
    99961 atacgacgaa agccgccacg ctggatgtta tctatacggt gatcaccagc ccggattcgc
   100021 cgagtgcgaa attctggggg catatgccgg acacctttac cagctcgacg ggcgtcacct
   100081 tcaaacgacc gctgctgaaa gcagaaacca gctcaggctc atcgattagc tctaacggcg
   100141 aagtttggtc atatatgagc aacgcgcaaa atttaacatc gacagattgc ccgctcgaaa
   100201 atcaaccgcg cagtaatgag ctgttggatt tgtatagcga tcacccgaac ggcacgctaa
   100261 tgaccgacct ggggttaccc gtatatgcag gtaactggtg ggcctatgat atggtcatgc
   100321 tgagtggaac gtcgtggact tatcaactca tcagcctgaa agacggaacc attacgcaga
   100381 aggggacaac cagtgcgttg atgctttgcc tggcacagcc gcatccggcc ggcgtcagcg
   100441 taacattgac gtcatccgca caggatgacg ccagaaccac cagcaatggc ggccgtccca
   100501 gcgcgtcagc gaaaaaaggt aactcaatac cgattgtggt aacggtaaaa gatcgtgatg
   100561 gcaacccgtt ggcgggcgaa gcggtgacgc tcaaacgtga ttcagcgttg agccgttcag
   100621 gaacaatcgt ggggacgcca gcgaatgaaa taaagttgac ggaactgacg cccgtgtcgg
   100681 cgacattccc gctggtttca aatggtacac aatggcttgg tttcaccggt agcgatggta
   100741 cggcgacatt caatgttgaa cagcctgata ctgtcggcct ggcaatcccc tttaacgcca
   100801 tcctggcccg tgacacggcc agggtatcta ctctggatct gatttttacc gtcctcacca
   100861 gcccggatgc cgcattagca acttactggg gccatatgcc ggataccgtc acggcggaaa
   100921 acggtgctgt ctttgagcgc cctaaactgt ggaaagagct gccgtcgaca tccggggtaa
   100981 gtcagataac gaatagcaat gaagcctggc cagtgtttaa cgcaacgcag agggctgaca
   101041 gcaatctcag cccttgtgaa gcggcgcgtc gaccattgag cgatgattta gaagcgctct
   101101 atacacgtta tccaggaaac acgattaccg cgcaaattgg ctggcctacg cagtatgcat
   101161 ggtgggcggt ggataactgg gaagggggca gtaatccgca ggccgtcagc ctggtaaatg
   101221 gttcgagagg ccaatataat cccgctcatc aggcctgcct ggttaacccg cgtgcgagcg
   101281 tttccagcgt cacgctgaca tcaacggcgc tggatgacgc cacacaggcg gcgacggtga
   101341 aaaaaggcga cgccgcgccc attgtcgtta ccgtaaaaga cagcgccggg aagccggtgc
   101401 cgaatatcgc ttttatccta aaacgcggtg aggccgtgcc gcgtaacagc ggggcgacgc
   101461 tgtatggcga tgtggatgcg atggacgatt tgactgtgca accttcatcc ggtgcggcag
   101521 tcacgttggc tgacagtgga aataccatcg acggagtcac gggagcggac ggtacggcaa
   101581 gctttaccgt tcgtcaggat aatacgccag gatataaaac gccgttgacg gtgacgctaa
   101641 cggataacgc caccataacg gcgacgctgg acacgatttt caccgtgccg accagcccga
   101701 atgtcgccac ggcgtatttc tggggtcata tggcggatac cgccacggta agtggcaaga
   101761 cgctgcatcg cccgctatta aaatcggagt tgccgtcagg cgctaccgca gcagcaacgc
   101821 ctgatgtaaa taatgaaacc tgggcactgg cgcatgttat ggattcctct aaatgggatg
   101881 tcgcgcagca gtgtggcagt atgaataacg tgccgagcag tgccgaatta caaacattac
   101941 actccggctt tagcacattg ggatggccgt cctcgataag cttcccgtat ttatctactg
   102001 ataaggctgg gtcgttctat tgtggtgttg atgaaggctc tggcagtctc aactgtggca
   102061 ttcagcctgc gaaaacgccg gggtttgcaa cctgtttcca ataaccttat ccaccttgtc
   102121 aatatgaggt tctgaaagcc tgatacgcaa cgcgctatca ggctttttta cgtggcttgc
   102181 ggcttttcgt caccgcactc acttcactga tcactacgcc atcgcccagg cgagtggtca
   102241 gtgtctcacc cactttcacc tgcttaacct gttttaacac cgcgccatca gcggcgctgg
   102301 taacgctata accgcgagcg agtgtggaca gtggactcac cgcttcgaga tgcgttactg
   102361 cattaccgaa acgttcacgc gtggcgctaa gctgtgcgcg cagggtttct gctaaacgat
   102421 attccagttg ctgaatgcgc gtttgcgcgc gatgaatctt cggctgtgga ttttgctgat
   102481 tcagccgctg tgttaatcgc tgctgctgtt gcccggcacg cttaagctga ttttccagcg
   102541 caaagctcat ccgtttttgc aggcgttcaa gcatggtttg ttggcgtgcc agccggagct
   102601 gtggatgctg ctgctgcaag cgatgatgga tctgcgtaaa acgacgcgtg cggttggcga
   102661 gataataatc catcgccatc tccagccgtt gacgggccga ttgcacctgg cgcagtaatt
   102721 cttgctgatt gcggctcact acttcagcgg cggcagacgg cgttggcgca cgcagatcag
   102781 caacaaagtc ggcaatcgtc acatccgtct catgcccgac ggcgctgacc accggaatgc
   102841 gactggcaaa gatcgcccgc gctacacgtt cgtcgttaaa actccacaaa tcttccagcg
   102901 aaccgccgcc gcgcccgacg atcagcacat cacattcgtt acgctgattc gccagttcaa
   102961 tggcgcgaac aatttgccct ggcgcgtcat caccctgaac ggcggtgggg tagatgatca
   103021 ccggcaaaga cggatcgcga cgttttaaca catgcaaaat atcatgtagc gcagcaccgg
   103081 tttttgaggt gatcacaccg acgcagtgcg cgggggaggg aagcggtttc tttaactgct
   103141 gatcgaacaa accttcagcc tgcaatttcg ctttaagctg ttcgtatttt tgttgcagca
   103201 acccttcacc ggcaggctgc atactctcga cgataatctg ataatcgccg cgcggttcat
   103261 agagtgtaat attggcgcgc actaaaactt gttgtccgtg ctgcgggcga aaggtcaccc
   103321 gacggttgct gttgcggaac atcgcacagc gcacctgggc ggtgtcgtct ttgagcgtaa
   103381 aataccagtg accggaagct ggttgtgtga aattagagat ttcgccgctg atccacacct
   103441 gtcccatctc atgctcaagc agcagacgaa ccgtttgatt caggcgacta acggtaaaaa
   103501 ttgcagggga ttgagaaggt aacatgtgag cgagatcaaa ttctaaatca gcaggttatt
   103561 cagtcgatag taacccgccc tccggggata gcaagcattt tttgcaaaaa ggggtagatg
   103621 caatcggtta cgctctgtat aatgccgcgg caatatttat taaccactct ggtcgagata
   103681 ttgcccatgc tacgtatcgc taaagaagct ctgacgtttg acgacgttct cctcgttcct
   103741 gctcattcta ccgttctgcc gaatactgct gacctcagca cccagctgac gaaaactatt
   103801 cgtctgaata tccctatgct ttccgcagca atggataccg taacggaagc gcgcctggct
   103861 attgctctgg ctcaggaagg cggtatcggc tttatccaca aaaacatgtc cattgaacgc
   103921 caggcagaag aagttcgccg tgtgaaaaaa cacgaatctg gcgtggtaac tgatccgcag
   103981 accgtgctgc cgacaaccac cctgcgtgaa gtgaaagaac tgactgaacg taacggcttt
   104041 gcgggttacc cggtggttac cgaagaaaac gaactggtcg gcatcatcac cggtcgtgac
   104101 gtgcgttttg tgaccgatct gaatcaaccg gttagcgttt acatgacgcc gaaagagcgt
   104161 ctggtaaccg tgcgtgaagg cgaagcccgt gaagtggtgc tggcaaaaat gcacgaaaaa
   104221 cgcgttgaaa aggcgctggt ggttgatgac gaattccacc tgatcggcat gatcactgtg
   104281 aaagacttcc agaaagcgga acgtaaaccg aacgcctgta aagacgagca aggccgtctg
   104341 cgtgttggtg cagcggttgg cgctggcgct ggtaacgaag agcgtgtcga cgcgctggtt
   104401 gccgcaggcg ttgacgttct gctgatcgac tcctctcacg gtcactctga aggcgttctg
   104461 cagcgtatcc gtgaaactcg tgctaaatat ccggatctgc aaatcatcgg cggcaacgtg
   104521 gcaacagctg cgggggcacg cgctctggca gaagctggtt gcagcgcggt taaagtcggt
   104581 atcggccctg gctctatctg tacgacgcgt atcgtgactg gcgtaggtgt tccgcagatc
   104641 accgccgttg ctgacgcagt agaagccctg gaaggcaccg ggattccggt tatcgctgac
   104701 ggtggtattc gtttctctgg cgatatcgcc aaagctatcg ctgctggtgc aagcgcggtg
   104761 atggtaggtt ccatgctggc gggtactgaa gaatccccag gtgaaatcga gctctaccag
   104821 ggccgttctt acaagtctta ccgtgggatg ggctctctgg gcgcgatgtc caaaggttct
   104881 tctgaccgtt acttccagag cgacaacgct gccgacaaac tggtgccgga aggtatcgaa
   104941 ggtcgcgtgg cctataaagg tcgcctgaaa gagatcattc accagcagat gggcggcctg
   105001 cgctcctgta tgggcctgac cggctgtggt actatcgacg aactgcgtac taaagcggag
   105061 tttgtacgta tcagcggtgc gggcattcag gaaagccacg ttcacgacgt gaccattact
   105121 aaagagtccc cgaactaccg tctgggctcc tgattctctt cgcccgactt catgtcgggc
   105181 gatttatatt atctgtttca cttgcctcgg aataagcgtc aatgacggaa aacattcata
   105241 agcatcgcat cctcattctg gacttcggtt ctcagtacac ccaactggtt gcgcgccgcg
   105301 tgcgtgaact gggtgtttac tgcgaactgt gggcgtggga tgtgacagaa gcacaaattc
   105361 gtgacttcaa tccaagcggc attattcttt ccggcggccc ggaaagcacc accgaagaaa
   105421 acagcccgcg tgcgccgcag tatgtctttg aagcaggcgt accggtattc ggcgtttgct
   105481 atggtatgca gaccatggca atgcagttgg gtggtcatgt tgaagcctct aacgaacgtg
   105541 aatttggcta tgcgcaggtt gaagtcgtaa acgacagcgc actggttcgc ggtatcgaag
   105601 atgctctgac agcagacggt aaacctctgc tcgatgtctg gatgagccac ggcgataaag
   105661 ttaccgctat cccgtccgac ttcatcaccg tagccagcac cgaaagctgc ccgttcgcca
   105721 tcatggctaa cgaagaaaaa cgcttctatg gcgtacagtt ccacccggaa gtgactcaca
   105781 ctcgccaggg tatgcgcatg ctggagcgtt ttgtgcgtga tatctgccag tgtgaagccc
   105841 tgtggacgcc agcgaaaatt atcgacgatg ctgtagctcg catccgcgag caggtaggcg
   105901 acgataaagt catcctcggc ctctctggtg gtgtggattc ctccgtaacc gcaatgctgc
   105961 tgcaccgcgc tatcggtaaa aacctgactt gcgtattcgt cgacaacggc ctgctgcgtc
   106021 tcaacgaagc agagcaggtt ctggatatgt ttggcgatca ctttggtctg aacattgttc
   106081 acgtaccggc agaagatcgc ttcctgtcag cgctggctgg cgaaaacgat ccggaagcaa
   106141 aacgtaaaat catcggtcgc gttttcgttg aagtattcga tgaagaagca ctgaaactgg
   106201 aagacgtgaa gtggctggcg cagggcacta tctaccctga cgttatcgaa tctgctgctt
   106261 ctgcaaccgg taaagcacat gtcatcaaat ctcaccacaa cgtgggcggc ctgccgaaag
   106321 agatgaagat gggcctggtt gaaccgctga aagagctgtt caaagacgaa gtgcgtaaga
   106381 ttggtctgga gctgggcctg ccgtacgaca tgctgtaccg tcacccgttc ccgggaccag
   106441 gccttggcgt tcgtgttctg ggtgaagtga agaaagagta ttgtgacctg ctgcgccgtg
   106501 ctgacgccat cttcattgaa gaactgcgta aagcggacct gtacgacaaa gtcagccagg
   106561 cgttcaccgt cttcctgccg gtacgttccg ttggcgtaat gggcgatggt cgtaagtatg
   106621 actgggttgt ctctctgcgt gctgtcgaaa ccatcgactt tatgaccgca cactgggcgc
   106681 atctgccgta cgatttcctc ggtcgcgttt ccaaccgcat tatcaatgaa gtgaacggta
   106741 tttcccgcgt ggtgtatgac atcagcggca agccgccagc taccattgag tgggaatgat
   106801 taacagctaa ctcatagcaa ctcattccta ttcagatact aatttaaccc tctgttttta
   106861 cagagggttt ttgtttttat gtattcattt ctattcacta tacaccatat ttttcgtcgg
   106921 tacaggtgac ggtattacct taaaggtata ctctcatacc gtcatgaaaa tggtttctat
   106981 acgggtgaat tgtgcttacc gatacaaaat taaaaaacct caagccgcag gacaaactgt
   107041 acaaggtctc cgatcgtgac gggctgtatg tagctgtgct tacgtcaggc acggtctcgt
   107101 ttcgctatga ctaccgtatc aacggtcgcc gcgaaacact ggtaatcggg cagtatgggc
   107161 gtgacggtat cagcctggca gaagcgcggg aagaactgat tgctgcaaag aagctgctta
   107221 aagcaggcca gtcaccggct gcggctaaac gtgacggtat caaaaagatt cgtggtgccg
   107281 agacgtttgc ggtacatacc gacagttata tgaaacacgt tatcctggct gacagtaccc
   107341 gcgcaatgaa gcaggcggtg atcgaccgtg acatacttcc ggttcttggc aacaaaatga
   107401 tggctgaaat taccacatcg atggttcgtg atttgtgtga ccggattgtc gaacgcggtg
   107461 gtcgggcaac agcagtacag gccagggaga tcatcagcag cgtataccgt cacgccaatg
   107521 accgtggtca tggtttgttt aatcctgcgg ctgacattaa accttcgtct atcgccatat
   107581 ttaaaccacg agagcgaaca ctgacaccag aagaaattgg cctgttcttc cgcacgctgg
   107641 atgccattgg tgctatgggc actatgaaaa tggctttaaa gctggtgctt atcactatgg
   107701 ttcgtaaagg cgaattcacc aatgcaacgt gggatgaaat agattttaaa aaatggacat
   107761 ggacaattcc ttcagaccgc atgaagggaa gccgggcgca cgttatttac ctgcctaaac
   107821 aggcacagga tatattggtt gggttgcaga tgtgcgctgg tggaagtgaa tatctggttc
   107881 ctggtcgtta caatttccgg aagccattat ctaatgccgc gctgaactct ctgatcgaca
   107941 gaacggtgaa aataataaat gaagatggtg agcatattca gggcttcacc gtacacgata
   108001 tgcgccgtac agccagtacg ttgttgcatg aggctggtta tccttcagac tggattgaaa
   108061 aggctctggc acatgagcag aaaggtgtgc gcgccgtata taacaaagcg gaatacgcca
   108121 gacagcgcgc ctacatgttg cagcagtggg ccgatatgat tgattcctgg attaacgggg
   108181 agcatacgga tctgattccg ttctccccgt cgaagtttga gaagtggatg gcgggggaat
   108241 aattttgccc ggcacatccc tgtgccgccg ccgtcagaag aaccctgcct tgtcgttgat
   108301 gtactccgcg tgcgtctgga tatcacgcag gcatttactc acaccgacga tgtagcagaa
   108361 catggtggtc agttccgccg ccgcgcccga tacgtcgtgc ccgtcttcct gtaacttgtt
   108421 cagcagattc atcagcagtg agttctccgt caggccgaga acaccagacg gagaatgaat
   108481 caggctgcgg tagccgggct tcagtggggc gctgtattct tttttgtctt ccagcttgat
   108541 cgcctccata atggcgggca tgaagcctga caagaccttc tccacttttg tttcttgttg
   108601 tcttaaacgt ttctcgcatt caatgaagta gcatcgtacc tgacgacctt tttcgttacg
   108661 ctcgaccatc gccagctctt tggctgtatc gagggtgagg tggtagtctt ttgcaggacg
   108721 gcctctgcct attttttccc gaacttggga aataatcata aagtcttgat tttcaacgaa
   108781 accatattca gcaattcgtt cgacaatcca cgaagcaaat cgcttaccta catcgaggaa
   108841 agagtgtaaa tcacgggcat taacgagaag agcggtttcg ttggatatag tgccgttgaa
   108901 tacggggatg agttgactgg tcatgatgac ctcctttgaa gttttagtta gcaatcacca
   108961 gttagtagct ggtgatcggg tgtcaactag agccttcaaa gacgctccgg gcatattccc
   109021 cttttgggta ttgtattacg cctctccacc cgacctttgt acggatgtga ctatgccaaa
   109081 ttgcaggcat aaaaaagccg caaagctatc gggtgcgggt gaccgctttg aagttctagt
   109141 gcggtcagta tgcgatagct ctggcggcat tgtcaaatca tgcgccactg agtccagcaa
   109201 tctctgcaat accaatagcg agataatcgc gattcgtcag gcgtgatttt attgcatatg
   109261 tcttagctcc actgaagttg tgattttata tgggttgcct tttacctcaa taacacgatg
   109321 aggatcattt tttagttctt ccgtaatctt ccgtaatgtt ctaacagctg aacttcggtg
   109381 tttataacgg taagttacag tttcttttct ctgcaatacc tcatcattgc ggtacttagt
   109441 caaaaccatg acgacttcaa acctgacgcc gttgtgtgca accataatct gcttcatgct
   109501 gcacgctccc gcccctggtt gtctgttggt gacagcggag cattgctgaa tgcatttgtt
   109561 aatccgccaa tatccaacgc gtatccgggg tgtagttgca ctgccgggtc ttcacactga
   109621 ttaccccaaa catcgaagcc atgagacgtc tggcgggcga acagttcaat gcgagaaaca
   109681 tcgcctaaca attgcacaag tttttcacga acgatatctg gttttcttga atgctcaagc
   109741 cgcggtgcgg taaatgactg aacgatccct gcattaatgc gcgtaggtag ttttcccttt
   109801 actgcaaaca ggcaatcttc actattggcg cgagtcatgt gacccatacc cataaccagt
   109861 ttatctggtt gtcgactacc acattttatc cacgtgaatc ccttcatggt catcagacgg
   109921 aatccccagg cctcaacaac ttttagtgct tcgagtggtt gtgttggcac ccaccacatg
   109981 gccaacagac agttttcatc ggccaaatcc cacacaggaa ggcggcagat atccagcaca
   110041 ctcataaccg gatatttaaa accggcaccg cgattaccat ctgcggcttt gtcccggtat
   110101 acccagggtg gatctgcata gattagtgtg tatttcttag tcataaacca ccccacaaca
   110161 tcctatgccg ctatagtcgc cacggcgaag gccgttacct tttgtgatac attggtccct
   110221 gcgaaccgcg atccttgcac gctcaacatc accagaagca acatccatac actgaagcca
   110281 aaggtgagcg gcaatgcgga actgcccttt tttctctctt tcaatcgcgc gtttttcgat
   110341 ctctatcgcc gcaggagtaa cggcgacaat ctttgacgga ctgcgcattg aaaccttgtt
   110401 catgtgatat ttttcaagtc ggcttaactt tctcacttaa tccaaccctc tctgaaaatt
   110461 aatgccagca gataaagcca tgctgaaaca gaggccagga ataagtacca tcctgaccat
   110521 ttgctccagt gccttagcag cacactcatg ccgcgttgct cacgggacga tatacacgtt
   110581 gctgaacagg aggtttttta ccctggaact ctgccgggct tgctgcctga cgttcatcaa
   110641 gccaacgctc aacttcatca cggttccatg cgcagcgttt atcggtgata taccagcgtt
   110701 taggaaattc ccctgcgcgc tccatacggt cgatagtgct ccatgacagt ggaaccaccg
   110761 ccaggagttc cttcttacct aatgcacctt tcataaatac ctctcttggt tgcagtgcgg
   110821 cgcgcgtggc gccgcggtgg tggttacata gatgtttcgt ttaattcttc ccgacgaacg
   110881 ctgtaaacgt cggtggcttt tgccagcagt tcgtcatcat ctgaaagttt ttgtgcaatg
   110941 tatttgtaag ccttatccag ttcggagaca gtgctgtaat tcatcgctgc gctggtaaag
   111001 gccatcagca tttcttctgg atcacggctg tccgatttac gcgtttgctc atcaggcttt
   111061 ttcgctggtt tagcgttgat cagactgttc attcccgcag cagtggtcgt ttgcggagta
   111121 atgtctcgct caacgcgcgg tgccgtttcc tgtaattcgt ctggggtgta gacgcccatg
   111181 attacgtcag gacagtgcag gcgagaccag cgttttgtcg caaggtatgc gagttgttgt
   111241 ttcggatcac tggcccaaag tgtggagttt cttacctgtg cttgagacag cattaactca
   111301 agcactcgag gttgatcctc gcccttcatg gttgcccata cgcgaacacc gcagccttct
   111361 tcgtctttta gagtccagcc tggtgcgata tatggattgc cgtttttgga tgttttctca
   111421 acaaacttac cgatcacgcg ttcccacggc ccgaaccact cgtagttgat gcgatctttt
   111481 gttggcgaca tcgttgagat aactgcgttt actaattggg cttcataacc tagcgtgccg
   111541 ttcacaacat gggttttctg agccacggca aacgggttca ttccccactg cgcagcctgc
   111601 attgccacgg ccatgcaatc agctggtttc ccggcgaggt gcgccggtac cgttacgcgg
   111661 ctttgcgcca ttacctcggc gaatttcatc agttggttca agccgtctgg gctgaaaata
   111721 gttgcagcag ttccagcgat tgctgtgtct actggtgcgt tgatgtttgc gatgtcgttg
   111781 ctcatatgta catatcctgt ttgcgtgccc actcagggcg tttaatgatt tccacaccgc
   111841 cccattcatc attgatgcgg cattcgtgat aggtattcag atcccggcgg aacagagcgt
   111901 gcccggcatc gacatcctgc gcatccagct cgaacacgcg taccggatac cgaccacaat
   111961 caatgctttc gctcacggca agaaagaaaa aaccatgcgg ctgaccagta accctcattg
   112021 cgccttcgcg gtacattgcg tcctgcacgt ggtagcggaa ttcctcgatg tggcgtgcaa
   112081 aacggtccat atctgcaacc tttttcacgt cgacgatcac gttgtgctcg ttcagccatt
   112141 tgtctggacg aattcggcac aactcccccg tctcttcatc gttccagtac attgatgctt
   112201 cgcagtaacc aggtgcttcc agcatccagc gtgccgccgg gtgagccatt gcgctatcac
   112261 gcatcagctc cagtttccgc cactgctcgg catcaagtac cgtaatcccc atatccgcca
   112321 catcacgaag aaattcctct tcgtcagctt taccttgttt cgtccgacga tcgaatttcg
   112381 gtgaaacaat gaagcgtttg tcgaactctc caggctccag aagcagacag tgcaatgcgg
   112441 ttcccatatc cagtgcagac tttttctctt cgtcttctgg tgctgcctga acccatttaa
   112501 gaagcgccgg attcttggca accatgtcca gttgcgactt actcacgccg tcaccggcgt
   112561 ggtagtcttc gttgctgatg tcgaaataaa ttcccggttt catgccgcgt ccctctgtcc
   112621 atcaagctga tccgccagat cccagcgggc gataattgcc attgcctctc gccgataggc
   112681 atccatcagt tcttcgaact cagggctgtc tttagcagcc tccagtactt cctggcgaac
   112741 gcctttaact gttacaacgt cgaaagttga tgccagttga tgaagccgga tactctcaat
   112801 cagttcaact tgtcggtcat atagctgttc tgacagacgg tagtccttgt cgaatgccag
   112861 catgattttt tgaagatttt tctgctgatt aacgttcatt atcagccctc ccatatctcg
   112921 ttatcgttgg ccacatcgcg agcttctttg ctgacgaaag cccacttaat gccttcctgt
   112981 aaggtgcgga acttccagct catgaatccg catgcagtaa cgcagtacca accgttgatg
   113041 attttccact gcataacttg ttacctcggt ctgttaccgt tgaggtaata attatgcgta
   113101 tatggtttga tgtcaataga tatgagttaa aaaaattacc cgttaggtaa tcgaataggc
   113161 aataaaaaag ccgccataag gcggcttact tactgaaaaa tatggtttta ttgtttgttt
   113221 ttttcgttct ggttgatgac aaattcaatg taactttcga tctttgcttt ctcggtttcg
   113281 ggtaacaatg cgtagcgcga gcgatcatag ttgatggtcg cagggtcgtg cgggtgaatc
   113341 agtaattcat agccgtgacg cccgaatgcg gatgcaacat tctccagggt ggaaatggaa
   113401 acgctgacct cattgtttaa caggcggctg attgtcacct gggctacgcc ggatgcgcgg
   113461 tgaagttttc cctgtgttga aaggtcgcgg ctttcgctca tccagcgttc caggttgtga
   113521 gccgccagct ggccaatgtc gcttgggccg acaggctgaa aaccttcctg agaaagcgag
   113581 cgatcgatat caagccagtt acggggttta ttggcggcag cttcaatttt tcgcgcaacc
   113641 tgatcgccga taaccttctt accaagagcc cagcggttta ccagatttgc ctgagttcca
   113701 agtttttcag ccatccgcgt ctgaacacca ttgaattcac ggtcgatcaa gtcgttgaga
   113761 ttttgcctgc ggacgtcctg gatacttttc attttctgga aaatcgcctc atatatgaat
   113821 cagtagatga ttcaatttaa agcaatatta cccaacaggt aaatgcacct catgggtaac
   113881 tatccttgat ttttgttacc ttatgggtga atatttatta tctgaaataa atatcaggca
   113941 atagctatga gcgataacgg acatttcgat ttcaaaaagc actggcttgc acttactccg
   114001 gatgagcgtg aagccttcgc acaggaagcc ggaacgacga gtcactatat ccagactcac
   114061 ttaacaggta agcgcaaaat gccaggtaaa gtattgatga atgggctttt taaagcctgt
   114121 aaaacaagac aatggctgcg ctcaaaagca gaactggcat acttcttcta ctcatgatat
   114181 ccagctacaa ccctctgtag accgccaccc ggcggtcttt tcatatctat tcgtacctca
   114241 aaggtaataa aaaaccaaat atggttgata ttttttttgt gtcagcacaa aatgaccgta
   114301 atcccaatac taataacagg gcttaccatg gaaatcatta cacgtattga tgccgcaaag
   114361 cgcggactta aacgctacta caccggaaaa acatgtaagc acggacatga cagtgaacgc
   114421 tgggtttaca acggacactg tgttgagtgc accatggaat caaaccgtcg tatcagggca
   114481 gagattaagc agatcatgat taattcctcc ccacaacatt caagctgata gcggagatta
   114541 atcatgagca gacatgcaac agattgggcc tgggagacag atccaggtag ctcatcatta
   114601 aagctcatac tgctctcgat ggctgacaga gccgatgaat ataacctctg ctaccccagc
   114661 atagaacgcc tcgttaaaga cacttgcctg aataaaaaaa ccgtgcaggc cgggcttata
   114721 tcgctcatga aaatggggct tatttcagat accggagaga gaaagggagc gacaaaaaga
   114781 gtgcgggttt tctctcttaa tataaccaaa aacgggaaca ttaaaggcaa ccgggagggg
   114841 ggcaatgaac ccgaaaacgg taatgttacc gaaaacggga atatacccaa aaacgggatg
   114901 ttgaatgatc ccaaaaacgg gatgttgaat gatcccaaaa acgggatcca gaaccagtca
   114961 tataaccagt catttaacca agagagggag agcaggacaa aaagcgggga ttctgtgcct
   115021 catgaccccg gagcaaacaa cgccgtgatg aataactttg ttcctcctgg tgggccaggg
   115081 caattaggca aatttgtcat gcatgaacaa tggcagccat cagatgactt tcttcggaaa
   115141 agctcattgc aggggatcta cctggacagt ctgccaacgg cacaggaact tgcagagttc
   115201 agaatttact ggatggctga gggtaaggca taccatcagg cacagtggga gcagaagctg
   115261 gcaaggcggc tgcagattag cagacagaag caatcaacat tacctgataa caacgttccg
   115321 cactggaaca gccctgaagc atgggaggat ttcttgtgaa caacgttttt accgcgatac
   115381 aaaaccgtga cggagaagcc ctttctcgca tgtcaggtta tgagcatcag tacgtcaaca
   115441 atgacaatgt ggtgaacatg tcagcagaga ggcttgttga tgcccttttt aaacagctga
   115501 aacaactgtt tccggcggca gtggtaacca acctgaagac gccagagcag gaagttgctg
   115561 caaaacagca gtggattgct gcgtttgccg aaggggggat ccgaacccgt gaacaggttt
   115621 ctgctggtat gcgccacgcc cgcgccagtg aatctccgtt ctggccgtct ccagggcaat
   115681 ttatcaagtg gtgcaaagac agcaagatgg ttcttggcgt caccattgac gatgtgatgg
   115741 cggagtttca ccggtacagc aaggaaaaaa gtttatatcc tggtggtccc gaaagattcc
   115801 cgtggcgaca tccggttatg tactgggtcg tatgtgatac ccgccgtgca atgtatcagc
   115861 gccagcttag cgagattgag gttgagaaac acgcacgcag gctgctcgat gattgggcga
   115921 aaaaggtggc ttccggacag cagatacccg atccggtgat cagcatacag gcaaagccag
   115981 agcccatgag tacgcctccg gacacaggga gagacgttta ccatccacca gggcgaagtt
   116041 tcgggtgcat gcctaacgcc gccacccttg ggggaataac accggcgcag tggctgatgg
   116101 aggaatacag gcggggaaag gcggcaggat ttatcaagta ataccagcgc gatagcgcat
   116161 tttttta
//
LOCUS       DADXDL010000003       116058 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.003, whole genome shotgun sequence.
ACCESSION   DADXDL010000003 DADXDL010000000
VERSION     DADXDL010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 116058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 116058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..116058
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.003"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            141..401
                     /gene="iraP"
                     /locus_tag="IRB70_000221"
     CDS             141..401
                     /gene="iraP"
                     /locus_tag="IRB70_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraP"
                     /protein_id="HBC0630182.1"
                     /translation="MKNLIAELLFKLAQKEEESKELCAQVEALEIIVTAMLRNMAQND
                     QQRLIDQVEGALYEVKPDASIPDDDTELLRDYVKKLLRHPRQ"
     gene            502..1917
                     /gene="phoA"
                     /locus_tag="IRB70_000222"
     CDS             502..1917
                     /gene="phoA"
                     /locus_tag="IRB70_000222"
                     /EC_number="3.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414917.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase"
                     /protein_id="HBC0630183.1"
                     /translation="MKQSTIALALLPLLFTPVTKARTPEMPVLENRAAQGDITAPGGA
                     RRLTGDQTAALRDSLSDKPAKNIILLIGDGMGDSEITAARNYAEGAGGFFKGIDALPL
                     TGQYTHYALNKKTGKPDYVTDSAASATAWSTGVKTYNGALGVDIHEKDHPTILEMAKA
                     AGLATGNVSTAELQDATPAALVAHVTSRKCYGPSATSEKCPGNALEKGGKGSITEQLL
                     NARADVTLGGGAKTFAETATVGEWQGKTLREQAQARGYQLVSDAASLNAVTEANQQKP
                     LLGLFADGNMPVRWLGPKATYHGNIDKPAVTCTPNPQRNDSVPTLAQMTDKAIELLSK
                     NEKGFFLQVEGASIDKQDHAANPCGQIGETVDLDEAVQRALEFAKKDGNTLVIVTADH
                     AHASQIVAPDTKAPGLTQALNTKDGAVMVMSYGNSEEDSQEHTGSQLRIAAYGPHAAN
                     VVGLTDQTDLFYTMKAALGLK"
     gene            2036..2356
                     /gene="psiF"
                     /locus_tag="IRB70_000223"
     CDS             2036..2356
                     /gene="psiF"
                     /locus_tag="IRB70_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414918.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PsiF"
                     /protein_id="HBC0630184.1"
                     /translation="MKITLLVTLLFGLVFLTTVGAAERTLTPQQQRMTSCNQQATAQA
                     LKGDARKTYMSDCLKNSKSAPGEKSLTPQQQKMRECNNQATQQSLKGDDRNKFMSACL
                     KKAA"
     gene            2458..3573
                     /gene="adrA"
                     /locus_tag="IRB70_000224"
                     /gene_synonym="dgcC"
     CDS             2458..3573
                     /gene="adrA"
                     /locus_tag="IRB70_000224"
                     /gene_synonym="dgcC"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase AdrA"
                     /protein_id="HBC0630185.1"
                     /translation="MFPKIMNDENFFKKAAAHGEEPPLTPQNEHQRSGLRFARRVRLP
                     RAVGLAGMFLPIASTLVSHPPPGWWWLVLVGWAFVWPHLAWQIASRAVDPLSREIYNL
                     KTDAVLAGMWVGVMGVNVLPSTAMLMIMCLNLMGAGGPRLFVAGLVLMVVSCLVTLEL
                     TGITVSFNSAPLEWWLSLPIIVIYPLLFGWVSYQTATKLAEHKRRLQVMSTRDGMTGV
                     YNRRHWETMLRNEFDNCRRHNRDATLLIIDIDHFKSINDTWGHDVGDEAIVALTRQLQ
                     ITLRGSDVIGRFGGDEFAVIMSGTPAESAITAMLRVHEGLNTLRLPNTPQVTLRISVG
                     VAPLNPQMSHYREWLKSADLALYKAKKAGRNRTEVAA"
     gene            complement(3590..4399)
                     /gene="proC"
                     /locus_tag="IRB70_000225"
     CDS             complement(3590..4399)
                     /gene="proC"
                     /locus_tag="IRB70_000225"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBC0630186.1"
                     /translation="MEKKIGFIGCGNMGKAILGGLIASGQVLPGQIWVYTPSPDKVAA
                     LHDQFGINAAESAQEVAQIADIIFAAVKPGIMIKVLSEITSSLNKDSLVVSIAAGITL
                     DQLARALGHDRKIIRAMPNTPALVNAGMTSVTPNALVTPEDTADVLNIFRCFGEAEVI
                     AEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMPRAQAYKFAAQAVMGSAKMVLET
                     GEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAMTKCMEKSEKLSKS"
     gene            4519..4977
                     /locus_tag="IRB70_000226"
     CDS             4519..4977
                     /locus_tag="IRB70_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414921.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBC0630187.1"
                     /translation="MTIWVDADACPNVIKEILYRAAERMQMPLVLVANQSLRVPPSRF
                     IRTLRVAAGFDVADNEIVRQCEAGDLVITADIPLAAEAIEKGAAALNPRGERYTPATI
                     RERLTMRDFMDTLRASGIQTGGPDSLSQRDRQAFAAELEKWWLEVQRSRG"
     gene            5160..5684
                     /gene="aroL"
                     /locus_tag="IRB70_000227"
     CDS             5160..5684
                     /gene="aroL"
                     /locus_tag="IRB70_000227"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroL"
                     /protein_id="HBC0630188.1"
                     /translation="MTQPLFLIGPRGCGKTTVGMALADSLNRRFVDTDQWLQSQLNMT
                     VAEIVEREEWTGFRARETAALEAVTAPSTVIATGGGIILTEFNRHFMQNNGIVVYLCA
                     PVSVLVNRLQAAPEEDLRPTLTGKPLSEEVQEVLEERDALYREVAHIIIDATNEPSQV
                     ISEIRSALAQTINC"
     gene            5734..5925
                     /gene="yaiA"
                     /locus_tag="IRB70_000228"
     CDS             5734..5925
                     /gene="yaiA"
                     /locus_tag="IRB70_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YaiA"
                     /protein_id="HBC0630189.1"
                     /translation="MPTKPPYPREAYIVTIEKGKPGQTVTWYQLRADHPKPDSLISEH
                     PTAQEAMDAKKRYEDPDKE"
     gene            6183..6860
                     /locus_tag="IRB70_000229"
     CDS             6183..6860
                     /locus_tag="IRB70_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AroM family protein"
                     /protein_id="HBC0630190.1"
                     /translation="MSASLAILTIGIVPMQEVLPLLTEYIDEDNISHHSLLGKLSREE
                     VMAEYAPEAGEDTILTLLNDNQLAHVSRRKVERDLQGVVEVLDNQGYDVIILMSTANI
                     SSMTARNTIFLEPSRILPPLVSSIVEDHQVGVIVPVEELLTVQAQKWQILQKPPVFSL
                     GNPIHDSEQKIIDAGKELLAKGADVIMLDCLGFHQRHRDLLQKQLDVPVLLSNVLIAR
                     LAAELLV"
     gene            6932..7216
                     /gene="ppnP"
                     /locus_tag="IRB70_000230"
     CDS             6932..7216
                     /gene="ppnP"
                     /locus_tag="IRB70_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine/purine nucleoside phosphorylase"
                     /protein_id="HBC0630191.1"
                     /translation="MLQSNEYFSGKVKSIGFSSSSTGRASVGVMVEGEYTFSTAEPEE
                     MTIISGALNVLLPDATDWQVYEAGSVFNVPGHSEFHLQVAEPTSYLCRYL"
     gene            7364..7702
                     /locus_tag="IRB70_000231"
                     /pseudo
     CDS             7364..7702
                     /locus_tag="IRB70_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308469.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing protein"
     gene            7699..7782
                     /locus_tag="IRB70_000232"
     CDS             7699..7782
                     /locus_tag="IRB70_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630192.1"
                     /translation="MTQRPWSKLQRKTHNIAAQNIIARRSE"
     gene            complement(7860..8771)
                     /gene="rdgC"
                     /locus_tag="IRB70_000233"
     CDS             complement(7860..8771)
                     /gene="rdgC"
                     /locus_tag="IRB70_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-associated protein RdgC"
                     /protein_id="HBC0630193.1"
                     /translation="MLWFKNLMVYRLSREISLRAEEMEKQLASMAFTPCGSQDMAKMG
                     WVPPMGSHSDALTHVANGQIVICARKEEKILPSPVIKQALEAKIAKLEAEQARKLKKT
                     EKDSLKDEVLHSLLPRAFSRFSQTMMWIDTVNGLIMVDCASAKKAEDTLALLRKSLGS
                     LPVVPLSMENPIELTLTEWVRSGSAAQGFQLLDEAELKSLLEDGGVIRAKKQDLTSEE
                     ITNHIEAGKVVTKLALDWQQRIQFVMCDDGSLKRLKFCDELRDQNEDIDREDFAQRFD
                     ADFILMTGELAALIQNLIEGLGGEAQR"
     gene            8896..9804
                     /gene="mak"
                     /locus_tag="IRB70_000234"
     CDS             8896..9804
                     /gene="mak"
                     /locus_tag="IRB70_000234"
                     /EC_number="2.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308471.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructokinase"
                     /protein_id="HBC0630194.1"
                     /translation="MRIGIDLGGTKTEVIALGDAGEQLYRHRLPTPRDDYRQTIETIA
                     TLVDMAEQATGQRGTVGMGIPGSISPYTGVVKNANSTWLNGQPFDKDLSARLQREVRL
                     ANDANCLAVSEAVDGAAAGAQTVFAVIIGTGCGAGVAFNGRAHIGGNGTAGEWGHNPL
                     PWMDEDELRYREEVPCYCGKQGCIETFISGTGFATDYRRLSGHALKGSEIIRLVEESD
                     PVAELALRRYELRLAKSLAHVVNILDPDVIVLGGGMSNVDRLYQTVPQLIKQFVFGGE
                     CETPVRKAKHGDSSGVRGAAWLWPQE"
     gene            complement(9944..11128)
                     /gene="araJ"
                     /locus_tag="IRB70_000235"
     CDS             complement(9944..11128)
                     /gene="araJ"
                     /locus_tag="IRB70_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414930.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter AraJ"
                     /protein_id="HBC0630195.1"
                     /translation="MKKVILSLALGTFGLGMAEFGIMGVLTELAHNVGISIPAAGHMI
                     SYYALGVVVGAPIIALFSSRYSLKHILLFLVALCVIGNAMFTLSSSYLMLAIGRLVSG
                     FPHGAFFGVGAIVLSKIIKPGKVTAAVAGMVSGMTVANLLGIPLGTYLSQEFSWRYTF
                     LLIAVFNIAVMASVYFWVPDIRDEAKGKLREQFHFLRSPAPWLIFAATMFGNAGVFAW
                     FSYVKPYMMFISGFSETAMTFIMMLVGLGMVLGNVLSGRISGRYSPLRIAAVTDFIIV
                     LALLMLFFFGGMKITSLIFAFICCAGLFALSAPLQILLLQNAKGGELLGAAGGQIAFN
                     LGSAVGAYCGGMMLTLGMAYNYVALPAALLSFAAMSSLLLYGRYKRQQAADSPVLAKP
                     LG"
     gene            complement(11254..14397)
                     /gene="sbcC"
                     /locus_tag="IRB70_000236"
     CDS             complement(11254..14397)
                     /gene="sbcC"
                     /locus_tag="IRB70_000236"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcC"
                     /protein_id="HBC0630196.1"
                     /translation="MKILSLRLKNLNSLKGEWKIDFTREPFASNGLFAITGPTGAGKT
                     TLLDAICLALYHETPRLSNVSQSQNDLMTRDTAECLAEVEFEVKGEVYRAFWSQNRAR
                     NQPDGNLQVPRVELARCADGKILADKVKDKLELTATLTGLDYGRFTRSMLLSQGQFAA
                     FLNAKPKERAELLEELTGTEIYGQISAMVFEQHKSARTELEKLQAQASGVALLTPEQV
                     QSLTASLQVLTDEEKQLLTAQQQEQQSLNWLTRLDELQQEASRRQQALQQALAEEEKA
                     QPQLAALSLAQPARNLRPHWERIAEHSAALAHTRQQIEEVNTRLQSTMALRASIRHHA
                     AKQSAELQQQQQSLNAWLQEHDRFRQWNNELAGWRAQFSQQTSDREHLRQWQQQLTHA
                     EQKLNALAAITLTLTADEVASALAQHAEQRPLRQRLVALHGQIVPQQKRLAQLQVTIQ
                     NVTQEQTQRNAALNEMRQRYKEKMQQLADVKTICEQEARIKTLEAQRAQLQAGQPCPL
                     CGSTSHPAVEAYQALEPGVNQSRLLALENEVKKLGEEGATLRGQLDALTKQLQRDENE
                     AQSLRQDEQALTQQWQAVTASLNITLQPQDDIQPWLDAQDEHERQLRLLSQRHEVQGQ
                     IAAHNQQIIQYQQQIEQRQQQLLTALAGYALTLPQEDEEESWLATRQQEAQSWQQRQN
                     ELTALQNRMQQLTPILETLPQSDELPHSEETVALENWRQVHEQCLALHSQQQTLQQQD
                     VLAAQSLQKAQAQFDTALQASVFDDQQAFLAALMDEQTLTQLEQLKQNLENQRRQAQT
                     LVTQTAEALAQHQQHRPDGLDLSVTVEQIQQELAQTQQKLRENTTSQGEIRQQLKQDA
                     DNRQQQQTLMQQIAQMTQQVEDWGYLNSLIGSKEGDKFRKFAQGLTLDNLVHLANQQL
                     TRLHGRYLLQRKASEALEVEVVDTWQADAVRDTRTLSGGESFLVSLALALALSDLVSH
                     KTRIDSLFLDEGFGTLDSETLDTALDALDALNASGKTIGVISHVEAMKERIPVQIKVK
                     KINGLGYSKLESAFAVK"
     gene            complement(14394..15596)
                     /gene="sbcD"
                     /locus_tag="IRB70_000237"
     CDS             complement(14394..15596)
                     /gene="sbcD"
                     /locus_tag="IRB70_000237"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001221323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease subunit SbcD"
                     /protein_id="HBC0630197.1"
                     /translation="MRILHTSDWHLGQNFYSKSREAEHQAFLDWLLETAQIHQVDAII
                     VAGDVFDTGSPPSYARTLYNRFVVNLQQTGCHLVVLAGNHDSVATLNESRDIMAFLNT
                     TVVASAGHAPQILPRRDGTPGAVLCPIPFLRPRDIITSQAGLNGIEKQQHLLAAITDY
                     YQQHYADACKLRGDQPLPIIATGHLTTVGASKSDAVRDIYIGTLDAFPAQNFPPADYI
                     ALGHIHRAQIIGGMEHVRYCGSPIPLSFDECGKSKYVHLVTFSNGKLENVENLNVPVT
                     QPMAVLKGDLASITAQLEQWRDVSQEPPVWLDIEITTDEYLHDIQRKIQALTESLPVE
                     VLLVRRSREQRERVLASQQRETLSELSVEEVFNRRLALEELDESQQQRLQYLFTTTLH
                     TLAGEHEV"
     gene            15786..16475
                     /gene="phoB"
                     /locus_tag="IRB70_000238"
     CDS             15786..16475
                     /gene="phoB"
                     /locus_tag="IRB70_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000113934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate response regulator transcription
                     factor PhoB"
                     /protein_id="HBC0630198.1"
                     /translation="MARRILVVEDEAPIREMVCFVLEQNGFQPVEAEDYDSAVNQLNE
                     PWPDLILLDWMLPGGSGIQFIKHLKRESMTRDIPVVMLTARGEEEDRVRGLETGADDY
                     ITKPFSPKELVARIKAVMRRISPMAVEEVIEMQGLSLDPTSHRVMAGEEPLEMGPTEF
                     KLLHFFMTHPERVYSREQLLNHVWGTNVYVEDRTVDVHIRRLRKALEPGGHDRMVQTV
                     RGTGYRFSTRF"
     gene            16533..17828
                     /gene="phoR"
                     /locus_tag="IRB70_000239"
     CDS             16533..17828
                     /gene="phoR"
                     /locus_tag="IRB70_000239"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate regulon sensor histidine kinase PhoR"
                     /protein_id="HBC0630199.1"
                     /translation="MLERLSWKRLVLELLLCCLPAFILGAFFGYLPWFLLASVTGLLI
                     WHFWNLLRLSWWLWVDRSMTPPPGRGSWEPLLYGLHQMQLRNKKRRRELGNLIKRFRS
                     GAESLPDAVVLTTEEGGIFWCNGLAQQILGLRWPEDNGQNILNLLRYPEFTQYLKTRD
                     FSRPLNLVLNTGRHLEIRVMPYTHKQLLMVARDVTQMHQLEGARRNFFANVSHELRTP
                     LTVLQGYLEMMDEQPLEGAVREKALHTMREQTQRMEGLVKQLLTLSKIEAAPTHLLNE
                     KVDVPMMLRVVEREAQTLSQKKQTFTFEIDNGLKVSGNEDQLRSAISNLVYNAVNHTP
                     EGTHITVRWQRVPHGAEFSVEDNGPGIAPEHIPRLTERFYRVDKARSRQTGGSGLGLA
                     IVKHAVNHHESRLNIESTVGKGTRFSFVIPERLIAKNSD"
     gene            18235..19554
                     /gene="brnQ"
                     /locus_tag="IRB70_000240"
     CDS             18235..19554
                     /gene="brnQ"
                     /locus_tag="IRB70_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transporter carrier
                     protein BrnQ"
                     /protein_id="HBC0630200.1"
                     /translation="MTHQLRSRDIIALGFMTFALFVGAGNIIFPPMVGLQAGEHVWTA
                     AFGFLITAVGLPVLTVVALAKVGGGVDSLSTPIGKVAGVLLATVCYLAVGPLFATPRT
                     ATVSFEVGIAPLTGDSALPLFIYSLVYFAIVILVSLYPGKLLDTVGNFLAPLKIIALV
                     ILSVAAIIWPAGSISTATEAYQNAAFSNGFVNGYLTMDTLGAMVFGIVIVNAARSRGV
                     TEARLLTRYTVWAGLMAGVGLTLLYLALFRLGSDSASLVDQSANGAAILHAYVQHTFG
                     GGGSFLLAALIFIACLVTAVGLTCACAEFFAQYVPLSYRTLVFILGGFSMVVSNLGLS
                     QLIQISVPVLTAIYPPCIALVVLSFTRSWWHNSTRVIAPPMFISLLFGILDGIKASAF
                     SDILPSWAQRLPLAEQGLAWLMPTVVMVVLAIIWDRAAGRQVTSSAH"
     gene            19630..21003
                     /gene="proY"
                     /locus_tag="IRB70_000241"
     CDS             19630..21003
                     /gene="proY"
                     /locus_tag="IRB70_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline-specific permease ProY"
                     /protein_id="HBC0630201.1"
                     /translation="MESKNKLKRGLSTRHIRFMALGSAIGTGLFYGSADAIKMAGPSV
                     LLAYIIGGVAAYIIMRALGEMSVHNPAASSFSRYAQENLGPLAGYITGWTYCFEILIV
                     AIADVTAFGIYMGVWFPTVPHWIWVLSVVLIICAVNLMSVKVFGELEFWFSFFKVATI
                     IIMIVAGFGIIIWGIGNGGQPTGIHNLWSNGGFFSNGWLGMVMSLQMVMFAYGGIEII
                     GITAGEAKDPEKSIPRAINSVPMRILVFYVGTLFVIMSIYPWNQVGTAGSPFVLTFQH
                     MGITFAASILNFVVLTASLSAINSDVFGVGRMLHGMAEQGSAPKIFSKTSRRGIPWVT
                     VLVMTTALLFAVYLNYIMPENVFLVIASLATFATVWVWIMILLSQIAFRRRLPPEEVK
                     ALKFKVPGGVATTICGLIFLLFIIGLIGYHPDTRISLYVGFAWIVVLLIGWMFKRRHD
                     RQLAENQ"
     gene            21159..22976
                     /gene="malZ"
                     /locus_tag="IRB70_000242"
     CDS             21159..22976
                     /gene="malZ"
                     /locus_tag="IRB70_000242"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308480.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin glucosidase"
                     /protein_id="HBC0630202.1"
                     /translation="MMLNAWHLPVPPFVKQSKDQLLITLWLTGEDPPQRIMLRTEHDN
                     EETSVAMHKQRSQPQPGVTAWRAAIDLSSGQPRRRYSFKLLWHDRQRWFTPQGFSRMP
                     PARLEQFAVDVPDIGPQWAADQIFYQIFPDRFARSLPREAEQDHVYYHHAAGQEIILR
                     DWDEPVTAQAGGSTFYGGDLDGISEKLPYLKKLGVTALYLNPVFKAPSVHKYDTEDYR
                     HVDPQFGGDGALLRLRHHTQQLGMRLVLDGVFNHSGDSHAWFDRHNRGTGGACHNPES
                     PWRDWYSFSDDGTALDWLGYASLPKLDYQSESLVNEIYRGEDSIVRHWLKAPWNMDGW
                     RLDVVHMLGEAGGARNNLQHVAGITEAAKETQPEAYIVGEHFGDARQWLQADVEDAAM
                     NYRGFTFPLWGFLANTDISYDPQQIDAQTCMAWMDNYRAGLSHQQQLRMFNQLDSHDT
                     ARFKTLLGRDIARLPLAVVWLFTWPGVPCIYYGDEVGLDGKNDPFCRKPFPWQVEKQD
                     TALFALYQRMIALRKKSQALRRGGCQVLYAEDNVVVFGRVLNQQRVLVAINRGEACEV
                     VLPASPLLNVAQWQRKEGHGQLTDGILALPAISATVWIN"
     gene            23163..24608
                     /locus_tag="IRB70_000243"
     CDS             23163..24608
                     /locus_tag="IRB70_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630203.1"
                     /translation="MTISNSNLLKPFITGTELPPFKEDVFSKTEEQFKKSPHGKLLFI
                     SGNENLVNISAEKIDEIKNSKDFFSNIVNIIILLIKHPDKILPILHGCPAESIELIKN
                     AKRTGQWSYEMTDKNGQNIEVSYIFTDTIDDKSDGKLCLKICNSCNQNDSSTHEYKID
                     HQQLKNHIRQLEEWALLEKFYDNNAYYSKRTKQLEKKIADAGFITGKVNADNFNVKEF
                     KDDIASMLCEQPPMRTHQISSSGYLSADKVPDLYKTNLKDAQRDLKTTSVDIDGVSLK
                     SKTREKIAEKIAKKTEEKIAKQNAKTIEEKNSEKNKKETNPEDNFVLKFSPEEINEML
                     LDYSDEEQKKLRPFFTSDHIYCLFDAFSQGLHNVARNGSPRYTGLLHQIASNSEILQD
                     FDQQLFWRTFSGGVFHRRISVNSEPEKTDVWRFSTQFDFPHINDNGELSRTVLMFEGV
                     AESNFKDIANHSSECFSYSCYAAPLDANAKK"
     gene            complement(24629..25210)
                     /gene="acpH"
                     /locus_tag="IRB70_000244"
     CDS             complement(24629..25210)
                     /gene="acpH"
                     /locus_tag="IRB70_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP phosphodiesterase"
                     /protein_id="HBC0630204.1"
                     /translation="MNFLAHLHLAHLAESSLSGNLLADFVRGNPEESFPPDVVAGIHM
                     HRRIDVLTDNLPEVREAREWFRSETRRVAPITLDVMWDHFLSRHWSQLSPDFPLQEFV
                     CYAREQVMTILPDSPPRFINLNNYLWSEQWLVRYRDMDFIQNVLNGMASRRPRLDALR
                     DSWYDLNAHYAALETRFWQFYPRMMAQASRKAL"
     gene            25303..26373
                     /gene="queA"
                     /locus_tag="IRB70_000245"
     CDS             25303..26373
                     /gene="queA"
                     /locus_tag="IRB70_000245"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBC0630205.1"
                     /translation="MRVTDFSFELPESLIAHYPMPERSSCRLLSLDGPTGALTHGTFT
                     DLLDKLNPGDLLVFNNTRVIPARLFGRKASGGKIEVLVERMLDDKRILAHIRASKAPK
                     PGAELLLGDDESINATMTARHGALFEVEFNDDRSVLDILNSIGHMPLPPYIDRPDEDA
                     DRELYQTVYSEKPGAVAAPTAGLHFDEPLLEKLRAKGVEMAFVTLHVGAGTFQPVRVD
                     TIEDHIMHSEYAEVPQDVVDAVLAAKARGNRVIAVGTTSVRSLESAAQAAKNDLIEPF
                     FDDTQIFIYPGFQYKVVDALVTNFHLPESTLIMLVSAFAGYQHTMNAYKAAVEEKYRF
                     FSYGDAMFITYNPQAINERVGE"
     gene            26428..27555
                     /gene="tgt"
                     /locus_tag="IRB70_000246"
     CDS             26428..27555
                     /gene="tgt"
                     /locus_tag="IRB70_000246"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBC0630206.1"
                     /translation="MKFELDTTDGRARRGRLVFDRGVVETPCFMPVGTYGTVKGMTPE
                     EVEATGAQIILGNTFHLWLRPGQEIMKLHGDLHDFMQWKGPILTDSGGFQVFSLGDIR
                     KITEQGVHFRNPINGDPIFLDPEKSMEIQYDLGSDIVMIFDECTPYPADWDYAKRSME
                     MSLRWAKRSRERFDSLGNKNALFGIIQGSVYEDLRDISVKGLVDIGFDGYAVGGLAVG
                     EPKADMHRILEHVCPQIPADKPRYLMGVGKPEDLVEGVRRGIDMFDCVMPTRNARNGH
                     LFVTDGVVKIRNAKYKSDTGPLDPECDCYTCRNYSRAYLHHLDRCNEILGARLNTIHN
                     LRYYQRLMAGLRKAIEEGKLESFVTDFYQRQGREVPPLNVD"
     gene            27578..27910
                     /gene="yajC"
                     /locus_tag="IRB70_000247"
     CDS             27578..27910
                     /gene="yajC"
                     /locus_tag="IRB70_000247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBC0630207.1"
                     /translation="MSFFISDAVAATGAPAQGSPMSLILMLVVFGLIFYFMILRPQQK
                     RTKEHKKLMDSIAKGDEVLTNGGLVGRVTKVAENGYIAIALNDTTEVVIKRDFVAAVL
                     PKGTMKAL"
     gene            27938..29785
                     /gene="secD"
                     /locus_tag="IRB70_000248"
     CDS             27938..29785
                     /gene="secD"
                     /locus_tag="IRB70_000248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecD"
                     /protein_id="HBC0630208.1"
                     /translation="MLNRYPLWKYVMLIVVIVIGLLYALPNLFGEDPAVQITGARGVA
                     ASEQTLIQVQKTLQEEKITAKSVALEEGAILARFDSTDTQLRAREALMGVMGDKYVVA
                     LNLAPATPRWLAAIHAEPMKLGLDLRGGVHFLMEVDMDTALGKLQEQNIDSLRSDLRE
                     KGIPYTTVRKENNYGLSITFRDAKARDEAIAYLSKRHPDLVISSQGSNQLRAVMSDAR
                     LSEAREYAVQQNINILRNRVNQLGVAEPVVQRQGADRIVVELPGIQDTARAKEILGAT
                     ATLEFRLVNTNVDQAAAASGRVPGDSEVKQTREGQPVVLYKRVILTGDHITDSTSSQD
                     EYNQPQVNISLDSAGGNIMSNFTKDNIGKPMATLFVEYKDSGKKDANGRAVLVKQEEV
                     INIANIQSRLGNSFRITGINNPNEARQLSLLLRAGALIAPIQIVEERTIGPTLGMQNI
                     EQGLEACLAGLLVSILFMIIFYKKFGLIATSALIANLILIVGIMSLLPGATLSMPGIA
                     GIVLTLAVAVDANVLINERIKEELSNGRTVQQAIDEGYRGAFSSIFDANITTLIKVII
                     LYAVGTGAIKGFAITTGIGVATSMFTAIVGTRAIVNLLYGGKRVKKLSI"
     gene            29796..30767
                     /gene="secF"
                     /locus_tag="IRB70_000249"
     CDS             29796..30767
                     /gene="secF"
                     /locus_tag="IRB70_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein translocase subunit SecF"
                     /protein_id="HBC0630209.1"
                     /translation="MAQEYTVEQLNHGRKVYDFMRWDYWAFGISGLLLIAAIVIMGVR
                     GFNWGLDFTGGTVIEITLEKPAEIDVMRDALQKAGFEEPMLQNFGSSHDIMVRMPPAE
                     GETGGQVLGSQVLKVINESTNQNAAVKRIEFVGPSVGADLAQTGAMALMAALLSILVY
                     VGFRFEWRLAAGVVIALAHDVIITLGILSLFHIEIDLTIVASLMSVIGYSLNDSIVVS
                     DRIRENFRKIRRGTPYEIFNVSLTQTLHRTLITSGTTLMVILMLYLFGGPVLEGFSLT
                     MLIGVSIGTASSIYVASALALKLGMKREHMLQQKVEKEGADQPSILP"
     gene            30896..31243
                     /locus_tag="IRB70_000250"
     CDS             30896..31243
                     /locus_tag="IRB70_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH nuclease family protein"
                     /protein_id="HBC0630210.1"
                     /translation="MAIIPKNYARLESGYREKALKIYPWVCGRCSREFVYSNLRELTV
                     HHIDHDHTNNPEDGSNWELLCLYCHDHEHSKYTEADQYGTTVIAGEDAQKDVGEAKYN
                     PFADLKAMMNKKK"
     gene            complement(31281..32165)
                     /gene="tsx"
                     /locus_tag="IRB70_000251"
     CDS             complement(31281..32165)
                     /gene="tsx"
                     /locus_tag="IRB70_000251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-specific channel-forming protein Tsx"
                     /protein_id="HBC0630211.1"
                     /translation="MKKTLLAAGAVLALSSSFTVNAAENDKPQYLSDWWHQSVNVVGS
                     YHTRFGPQIRNDTYLEYEAFAKKDWFDFYGYADAPVFFGGNSDAKGIWNHGSPLFMEI
                     EPRFSIDKLTNTDLSFGPFKEWYFANNYIYDMGRNKDGRQSTWYMGLGTDIDTGLPMS
                     LSMNVYAKYQWQNYGAANENEWDGYRFKIKYFVPITDLWGGQLSYIGFTNFDWGSDLG
                     DDSGNAINGIKTRTNNSIASSHILALNYDHWHYSVVARYWHDGGQWNDDAELNFGNGN
                     FNVRSTGWGGYLVVGYNF"
     gene            complement(32463..33002)
                     /locus_tag="IRB70_000252"
     CDS             complement(32463..33002)
                     /locus_tag="IRB70_000252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414946.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HBC0630212.1"
                     /translation="MNTNVFRLLLLGSLFSLSACVQQSEVRQMKHSVSTLNQEMTQLN
                     KETVKITQQNRLNAKSSSGVYLLPGAKTPARLESQIGTLRMSLVNITPDTDGTTLTLR
                     IQGESNDPLPAFSGTVEYGQIQGTIDNFQEINVQNQLINAPASVLAPSDVDIPLQLKG
                     MSVDQLGFVRIHDIQPVMQ"
     gene            33153..33602
                     /gene="nrdR"
                     /locus_tag="IRB70_000253"
     CDS             33153..33602
                     /gene="nrdR"
                     /locus_tag="IRB70_000253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NrdR"
                     /protein_id="HBC0630213.1"
                     /translation="MHCPFCFAVDTKVIDSRLVGEGSSVRRRRQCLVCNERFTTFEVA
                     ELVMPRVVKSNDVREPFNEEKLRSGMLRALEKRPVSSDDVEMAINHIKSQLRATGERE
                     VPSKMIGNLVMEQLKKLDKVAYIRFASVYRSFEDIKEFGEEIARLED"
     gene            33606..34709
                     /gene="ribD"
                     /locus_tag="IRB70_000254"
     CDS             33606..34709
                     /gene="ribD"
                     /locus_tag="IRB70_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     diaminohydroxyphosphoribosylaminopyrimidine
                     deaminase/5-amino-6-(5-phosphoribosylamino)uracil
                     reductase RibD"
                     /protein_id="HBC0630214.1"
                     /translation="MQDEYYMARALKLAQRGRFTTHPNPNVGCVIVKDGEIVGEGYHQ
                     RAGEPHAEVHALRMAGEKAKGATAYVTLEPCSHHGRTPPCCDALIAAGVARVVAAMQD
                     PNPQVAGRGLYRLQQAGIDVSHGLMMSEAEQLNKGFLKRMRTGFPYIQLKLGASLDGR
                     TAMASGESQWITSPQARRDVQRLRAQSHAILTSSATVLADDPALTVRWSELDEQTQAL
                     YPQQNLRQPIRIVIDSQNRVTPEHRIVQQPGETWFARTQDDSREWPETVRTLLIPEHK
                     GHLDLVVLMMQLGKQQINSIWVEAGPTLAGALLQAGLVDELIVYIAPKLLGSDARGLC
                     SLPGLEKLADAPQFKFKEIRHVGPDVCLHLVGA"
     gene            34798..35268
                     /gene="ribE"
                     /locus_tag="IRB70_000255"
     CDS             34798..35268
                     /gene="ribE"
                     /locus_tag="IRB70_000255"
                     /EC_number="2.5.1.78"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6,7-dimethyl-8-ribityllumazine synthase"
                     /protein_id="HBC0630215.1"
                     /translation="MNIIEANVATPDARVAITIARFNNFINDSLLEGAIDALKRIGQV
                     KDENITVVWVPGAYELPLAAGALAKTGKYDAVIALGTVIRGGTAHFEYVAGGASNGLA
                     HVAQDSEIPVAFGVLTTESIEQAIERAGTKAGNKGAEAALTALEMINVLKAIKA"
     gene            35288..35707
                     /gene="nusB"
                     /locus_tag="IRB70_000256"
     CDS             35288..35707
                     /gene="nusB"
                     /locus_tag="IRB70_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBC0630216.1"
                     /translation="MKPAARRRARECAVQALYSWQLSQNDIADVEYQFLAEQDVKDVD
                     VLYFRELLAGVATNTAYLDGLMKPYLSRLLEELGQVEKAVLRIALYELSKRSDVPYKV
                     AINEAIELAKSFGAEDSHKFVNGVLDKAAPVIRPNKK"
     gene            35785..36762
                     /gene="thiL"
                     /locus_tag="IRB70_000257"
     CDS             35785..36762
                     /gene="thiL"
                     /locus_tag="IRB70_000257"
                     /EC_number="2.7.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine-phosphate kinase"
                     /protein_id="HBC0630217.1"
                     /translation="MACGEFSLIARYFDRVRSSRLDVELGIGDDCALLNIPEKQTLAI
                     STDTLVAGNHFLPDIDPADLAYKALAVNLSDLAAMGADPAWLTLALTLPDVDEAWLES
                     FSDSLFDLLNYYDMQLIGGDTTRGPLSMTLGIHGFVPMGRALTRSGAKPGDWIYVTGT
                     PGDSAAGLAILQNRLQVADAKDADYLIKRHLRPSPRILQGQALRDLANSAIDLSDGLI
                     SDLGHIVKASDCGARIDLALLPFSDALSRHVEPEQALRWALSGGEDYELCFTVPELNR
                     GALDVALGHLGVPFTCIGQMTADIEGLCFIRDGEPVTLDWKGYDHFATP"
     gene            36740..37258
                     /gene="pgpA"
                     /locus_tag="IRB70_000258"
     CDS             36740..37258
                     /gene="pgpA"
                     /locus_tag="IRB70_000258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBC0630218.1"
                     /translation="MTILPRHKDVAKSRLKMSNPWHLLAVGFGSGLSPIVPGTMGSLA
                     AIPFWYLMTFLPWQLYSLVVMLGICIGVYLCHQTAKDMGVHDHGSIVWDEFIGMWITL
                     MALPTNDWQWVAAGFVIFRILDMWKPWPIRWFDRNVHGGMGIMIDDIVAGVISAGILY
                     FIGHHWPLGILS"
     gene            complement(37312..38286)
                     /gene="yajO"
                     /locus_tag="IRB70_000259"
     CDS             complement(37312..38286)
                     /gene="yajO"
                     /locus_tag="IRB70_000259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414953.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxyxylulose-5-phosphate synthase YajO"
                     /protein_id="HBC0630219.1"
                     /translation="MQYKPLGKTDLRVSRLCLGCMTFGEPDRGNHAWTLPEESSRPII
                     KRALEGGINFFDTANSYSDGSSEEIVGRALRDFARREDVVVATKVFHRVGDLPEGLSR
                     AQILRSIDDSLRRLGMDYVDILQIHRWDYNTPIEETLEALNDVVKAGKARYIGASSMH
                     ASQFAQALELQKQHGWAQFVSMQDHYNLIYREEEREMLPLCYEEGVAVIPWSPLARGR
                     LTRPWGETTARLVSDEVGKNLYKESDENDAQIAERLTGVSEELGATRAQVALAWLLSK
                     PGIAAPIIGTSREEQLDELLNAVDITLKPEQIAELETPYKPHPVVGFK"
     gene            complement(38341..40203)
                     /gene="dxs"
                     /locus_tag="IRB70_000260"
     CDS             complement(38341..40203)
                     /gene="dxs"
                     /locus_tag="IRB70_000260"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBC0630220.1"
                     /translation="MSFDIAKYPTLALVDSTQELRLLPKESLPKLCDELRRYLLDSVS
                     RSSGHFASGLGTVELTVALHYVYNTPFDQLIWDVGHQAYPHKILTGRRDKIGTIRQKG
                     GLHPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGKNRRTVCVIGDGAITAGMA
                     FEAMNHAGDIRPDMLVVLNDNEMSISENVGALNNHLAQLLSGKLYSSLREGGKKVFSG
                     VPPIKELLKRTEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQ
                     FLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYSKIFGDWLCETAA
                     KDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAVGLAIGGYKPIVAIY
                     STFLQRAYDQVLHDVAIQKLPVLFAIDRAGIVGADGQTHQGAFDLSYLRCIPEMVIMT
                     PSDENECRQMLYTGYHYNDGPSAVRYPRGNAVGVELTPLEKLPIGKGIVKRRGEKLAI
                     LNFGTLMPEAAKVAESLNATLVDMRFVKPLDEALILEMAASHEALVTVEENAIMGGAG
                     SGVNEVLMAHRKPVPVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWLA"
     gene            complement(40228..41127)
                     /gene="ispA"
                     /locus_tag="IRB70_000261"
     CDS             complement(40228..41127)
                     /gene="ispA"
                     /locus_tag="IRB70_000261"
                     /EC_number="2.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl diphosphate synthase"
                     /protein_id="HBC0630221.1"
                     /translation="MDFPQQLEACVKQANQALSRFIAPLPFQNTPVVETMQYGALLGG
                     KRLRPFLVYATGHMFGVSTNTLDAPAAAVECIHAYSLIHDDLPAMDDDDLRRGLPTCH
                     VKFGEANAILAGDALQTLAFSILSDADMPEVSDRDRISMISELASASGIAGMCGGQAL
                     DLDAEGKRVPLDALERIHRHKTGALIRAAVRLGALSAGDKGRRALPVLDKYAESIGLA
                     FQVQDDILDVVGDTATLGKRQGADQQLGKSTYPALLGLEQARKKARDLIDDARQSLKQ
                     LAEQSLDTSALEALADYIIQRNK"
     gene            complement(41127..41369)
                     /gene="xseB"
                     /locus_tag="IRB70_000262"
     CDS             complement(41127..41369)
                     /gene="xseB"
                     /locus_tag="IRB70_000262"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBC0630222.1"
                     /translation="MPKKNEAPASFEKALSELEQIVTRLESGDLPLEEALNEFERGVQ
                     LARQGQAKLQQAEQRVQILLSDNEDASLTPFTPDNE"
     gene            41575..43023
                     /gene="thiI"
                     /locus_tag="IRB70_000263"
     CDS             41575..43023
                     /gene="thiI"
                     /locus_tag="IRB70_000263"
                     /EC_number="2.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBC0630223.1"
                     /translation="MKFIIKLFPEITIKSQSVRLRFIKILTGNIRNVLKHYDETLAVV
                     RHWDNIEVRAKDENQRLAIRDALTRIPGIHHILEVEDVPFTDMHDIFEKALVQYRDQL
                     EGKTFCVRVKRRGKHDFSSIDVERYVGGGLNQHIESARVKLTNPDVTVHLEVEDDRLL
                     LIKGRYEGIGGFPIGTQEDVLSLISGGFDSGVSSYMLMRRGCRVHYCFFNLGGAAHEI
                     GVRQVAHYLWNRFGSSHRVRFVAINFEPVVGEILEKIDDGQMGVILKRMMVRAASKVA
                     ERYGVQALVTGEALGQVSSQTLTNLRLIDNVSDTLILRPLISYDKEHIINLARQIGTE
                     DFARTMPEYCGVISKSPTVKAVKSKIEAEEEKFDFSILDKVVEEANNVDIREIAQQTE
                     QEVVEVETVNGFGPNDVILDIRSIDEQEDKPLKVEGIDVVSLPFYKLSTKFGDLDQSK
                     TWLLWCERGVMSRLQALYLREQGFNNVKVYRP"
     gene            complement(43077..43667)
                     /gene="yajL"
                     /locus_tag="IRB70_000264"
     CDS             complement(43077..43667)
                     /gene="yajL"
                     /locus_tag="IRB70_000264"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase YajL"
                     /protein_id="HBC0630224.1"
                     /translation="MSASALVCLAPGSEETEAVTTIDLLVRGGIKVTTASVASDGNLA
                     ITCSRGVKMLADAPLVEVADGEYDVIVLPGGIKGAECFRDSTLLVETVKQFHRSGRIV
                     AAICAAPATVLVPHDIFPIGNMTGFPTLKDKIPAEQWQDKRVVWDARVKLLTSQGPGT
                     AIDFGLKIIDLLVGREKAHEVASQLVMAAGIYNYYE"
     gene            complement(43630..44541)
                     /gene="panE"
                     /locus_tag="IRB70_000265"
     CDS             complement(43630..44541)
                     /gene="panE"
                     /locus_tag="IRB70_000265"
                     /EC_number="1.1.1.169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBC0630225.1"
                     /translation="MKITVLGCGALGQLWLTALCKQGHDVQGWLRVPQPYCSVNLVET
                     DGSIFNESLTANDPDFLATSDLLLVTLKAWQVSDAVKSLASTLPVTTPILLIHNGMGT
                     IEELQNIQQPLLMGTTTHAARRDGNVIIHVANGITHIGPARQQDGDYSYLADILQTVL
                     PDVAWHNNIRAELWRKLAVNCVINPLTAIWNCPNGELRHHPQEIMQICEEVAAVIERE
                     GHHTSAEDLRDYVMQVIDATAENISSMLQDIRALRHTEIDYINGFLLRRARAHGIAVP
                     ENTRLFEMVKRKESEYERIGTGLPRPW"
     gene            44709..45200
                     /gene="yajQ"
                     /locus_tag="IRB70_000266"
     CDS             44709..45200
                     /gene="yajQ"
                     /locus_tag="IRB70_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414960.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide binding protein YajQ"
                     /protein_id="HBC0630226.1"
                     /translation="MPSFDIVSEVDLQEARNAVDNASREVESRFDFRNVEASFELNDA
                     SKTIKVLSESDFQVNQLLDILRAKLLKRGIEGSSLDVPENIVHSGKTWFVEAKLKQGI
                     ESATQKKIVKMIKDSKLKVQAQIQGDEIRVTGKSRDDLQAVMAMVRGGDLGQPFQFKN
                     FRD"
     gene            complement(45328..46692)
                     /locus_tag="IRB70_000267"
     CDS             complement(45328..46692)
                     /locus_tag="IRB70_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630227.1"
                     /translation="MNDYKMTPGERRATWGLGTVFSLRMLGMFMVLPVLTTYGMALQG
                     ASEALIGIAIGIYGLTQAVFQIPFGLLSDRIGRKPLIVGGLAVFAAGSVIAALSDSIW
                     GIILGRALQGSGAIAAAVMALLSDLTREQNRTKAMAFIGVSFGITFAIAMVLGPIITH
                     KLGLHALFWMIAILATTGIALTIWVVPNSSTHVLNRESGMVKGSFSKVLAEPRLLKLN
                     FGIMCLHILLMSTFVALPGQMADAGFPAAEHWKVYLATMLIAFGSVVPFIIYAEVKRK
                     MKQVFVFCVGLIVVAEIVLWNAQTQFWQLVVGVQLFFVAFNLMEALLPSLISKESPAG
                     YKGTAMGVYSTSQFLGVAIGGSLGGWIDGMFDGQGVFLAGAMLAAVWLAVASTMKEPP
                     YVSSLRIEIPADIAANNALKVRLLETEGVKEVLIAEEEHSAYVKIDSKVTNRFEVEQA
                     IRQA"
     gene            complement(46841..47731)
                     /gene="cyoE"
                     /locus_tag="IRB70_000268"
     CDS             complement(46841..47731)
                     /gene="cyoE"
                     /locus_tag="IRB70_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX farnesyltransferase"
                     /protein_id="HBC0630228.1"
                     /translation="MMFKQYLQVTKPGIIFGNLISVIGGFLLASKGSIDYPLFIYTLV
                     GVSLVVASGCVFNNYIDRDIDRKMERTKNRVLVKGLISPAVSLVYATLLGIAGFMLLW
                     FGANPLACWLGVMGFVVYVGVYSLYMKRHSVYGTLIGSLSGAAPPVIGYCAVTGEFDS
                     GAAILLAIFSLWQMPHSYAIAIFRFKDYQAANIPVLPVVKGISVAKNHITLYIIAFAV
                     ATLMLSLGGYAGYKYLVVAAAVSVWWLGMALRGYKVADDRIWARKLFGFSIIAITALS
                     VMMSVDFMVPDSHTLLAAVW"
     gene            complement(47743..48072)
                     /locus_tag="IRB70_000269"
     CDS             complement(47743..48072)
                     /locus_tag="IRB70_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit IV"
                     /protein_id="HBC0630229.1"
                     /translation="MSHSTDHSGASHGSVKTYMTGFILSIILTVIPFWMVMTGAASPA
                     VILGTILAMAVVQVLVHLVCFLHMNTKSDEGWNMTAFVFTVLIIAILVVGSIWIMWNL
                     NYNMMMH"
     gene            complement(48072..48686)
                     /locus_tag="IRB70_000270"
     CDS             complement(48072..48686)
                     /locus_tag="IRB70_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit III"
                     /protein_id="HBC0630230.1"
                     /translation="MATDTLTHATAHAHEHGHHDAGGTKIFGFWIYLMSDCILFSILF
                     ATYAVLVNGTAGGPTGKDIFELPFVLVETFLLLFSSITYGMAAIAMYKNNKSQVISWL
                     ALTWLFGAGFIGMEIYEFHHLIVNGMGPDRSGFLSAFFALVGTHGLHVTSGLIWMAVL
                     MVQIARRGLTSTNRTRIMCLSLFWHFLDVVWICVFTVVYLMGAM"
     gene            complement(48676..50667)
                     /gene="cyoB"
                     /locus_tag="IRB70_000271"
     CDS             complement(48676..50667)
                     /gene="cyoB"
                     /locus_tag="IRB70_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002444673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit I"
                     /protein_id="HBC0630231.1"
                     /translation="MFGKLSLDAVPFHEPIVMVTIAGIILGGLALVGLITYFGKWTYL
                     WKEWLTSVDHKRLGIMYIIVAIVMLLRGFADAIMMRSQQALASAGEAGFLPPHHYDQI
                     FTAHGVIMIFFVAMPFVIGLMNLVVPLQIGARDVAFPFLNNLSFWFTVVGVILVNVSL
                     GVGEFAQTGWLAYPPLSGIEYSPGVGVDYWIWSLQLSGIGTTLTGINFFVTILKMRAP
                     GMTMFKMPVFTWASLCANVLIIASFPILTVTVALLTLDRYLGTHFFTNDMGGNMMMYI
                     NLIWAWGHPEVYILILPVFGVFSEIAATFSRKRLFGYTSLVWATVCITVLSFIVWLHH
                     FFTMGAGANVNAFFGITTMIIAIPTGVKIFNWLFTMYQGRIVFHSAMLWTIGFIVTFS
                     VGGMTGVLLAVPGADFVLHNSLFLIAHFHNVIIGGVVFGCFAGMTYWWPKAFGFKLNE
                     TWGKRAFWFWIIGFFVAFMPLYALGFMGMTRRLSQQIDPQFHTMLMIAASGAVLIALG
                     ILCLVIQMYVSIRDRDQNRDLTGDPWGGRTLEWATSSPPPFYNFAVVPHVHERDAFWE
                     MKEKGEAYKKPDHYEEIHMPKNSGAGIVIAAFSTIFGFAMIWHIWWLAIVGFAGMIIT
                     WIVKSFDEDVDYYVPVAEIEKLENQHFDEITKAGLKNGN"
     gene            complement(50689..51636)
                     /gene="cyoA"
                     /locus_tag="IRB70_000272"
     CDS             complement(50689..51636)
                     /gene="cyoA"
                     /locus_tag="IRB70_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome o ubiquinol oxidase subunit II"
                     /protein_id="HBC0630232.1"
                     /translation="MRLRKYNKSLGWLSLFAGTVLLSGCNSALLDPKGQIGLEQRSLI
                     LTAFGLMLIVVIPAILMAVGFAWKYRASNKDAKYSPNWSHSNKVEAVVWTVPILIIIF
                     LAVLTWKTTHALEPSKPLAHDEKPITIEVVSMDWKWFFIYPEQGIATVNEIAFPANTP
                     VYFKVTSNSVMNSFFIPRLGSQIYAMAGMQTRLHLIANEPGTYDGISASYSGPGFSGM
                     KFKAIATPDRAAFDQWVAKAKQSPNTMSDMAAFEKLAAPSEYNQVEYFSNVKPDLFAD
                     VINKFMAHGKSMDMTQPEGEHSAHEGMEGMDMSHAESAH"
     gene            complement(52096..53571)
                     /gene="ampG"
                     /locus_tag="IRB70_000273"
     CDS             complement(52096..53571)
                     /gene="ampG"
                     /locus_tag="IRB70_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muropeptide MFS transporter AmpG"
                     /protein_id="HBC0630233.1"
                     /translation="MSSQYLRIFQQPRSAILLILGFASGLPLALTSGTLQAWMTVENI
                     DLKTIGFFSLVGQAYVFKFLWSPLMDRYTPPFFGRRRGWLLATQILLLVAIAAMGFLE
                     PGTQLRWMAALAVVIAFCSASQDIVFDAWKTDVLPAEERGAGAAISVLGYRLGMLVSG
                     GLALWLADKWLGWQGMYWLMAALLIPCIIATLLAPEPTDTIPVPKTLEQAVVAPLRDF
                     FGRNNAWLILLLIVLYKLGDAFAMSLTTTFLIRGVGFDAGEVGVVNKTLGLLATIVGA
                     LYGGILMQRLSLFRALLIFGILQGASNAGYWLLSITDKHLYSMGAAVFFENLCGGMGT
                     SAFVALLMTLCNKSFSATQFALLSALSAVGRVYVGPVAGWFVEAHGWSTFYLFSVAAA
                     VPGLILLLICRQTLEYTRVNDNFISRTEYPAGYAFAMWTLAAGVSLLAVWLLLLTMDA
                     LDLTHFSFLPALLEVGVLVALSGVVLGGLLDYLALRKTHLT"
     gene            complement(53615..54193)
                     /locus_tag="IRB70_000274"
     CDS             complement(53615..54193)
                     /locus_tag="IRB70_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414968.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBC0630234.1"
                     /translation="MFKKILFPLVALFMLAGCAKPPTTIEVSPTITLPQQDPSLMGVT
                     VSINGADQRTDQALAKVTRDNQIVTLTASRDLRFLLQEVLEKQMTARGYMVGPNGPVN
                     LQIIVSQLYADVSQGNVRYNIATKADIAIIATAQNGNKMTKNYRASYNVEGAFQASNK
                     NIADAVNSVLTDTIADMSQDTSIHEFIKQNAR"
     gene            54498..54815
                     /gene="bolA"
                     /locus_tag="IRB70_000275"
     CDS             54498..54815
                     /gene="bolA"
                     /locus_tag="IRB70_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414969.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BolA"
                     /protein_id="HBC0630235.1"
                     /translation="MMIRERIEEKLRAAFQPVFLEVVDESYRHNVPAGSESHFKVVLV
                     SDRFTGERFLNRHRMIYSTLAEELSTTVHALALHTYTIKEWEGLQDTVFASPPCRGAG
                     SIA"
     gene            55159..56457
                     /gene="tig"
                     /locus_tag="IRB70_000276"
     CDS             55159..56457
                     /gene="tig"
                     /locus_tag="IRB70_000276"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBC0630236.1"
                     /translation="MQVSVETTQGLGRRVTITIAADSIETAVKSELVNVAKKVRIDGF
                     RKGKVPMNIVAQRYGASVRQDVLGDLMSRNFIDAIIKEKINPAGAPTYVPGEYKLGED
                     FTYSVEFEVYPEVELQGLEAIEVEKPIVEVTDADVDGMLDTLRKQQATWKEKDGAVEA
                     EDRVTIDFTGSVDGEEFEGGKASDFVLAMGQGRMIPGFEDGIKGHKAGEEFTIDVTFP
                     EEYHAENLKGKAAKFAINLKKVEERELPELTAEFIKRFGVEDGSVEGLRAEVRKNMER
                     ELKSAIRNRVKSQAIEGLVKANDIDVPAALIDSEIDVLRRQAAQRFGGNEKQALELPR
                     ELFEEQAKRRVVVGLLLGEVIRTNELKADEERVKGLIEEMASAYEDPKEVIEFYSKNK
                     ELMDNMRNVALEEQAVEAVLAKAKVTEKETTFNELMNQQA"
     gene            56703..57326
                     /gene="clpP"
                     /locus_tag="IRB70_000277"
     CDS             56703..57326
                     /gene="clpP"
                     /locus_tag="IRB70_000277"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006809880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBC0630237.1"
                     /translation="MSYSGERDNFAPHMALVPMVIEQTSRGERSFDIYSRLLKERVIF
                     LTGQVEDHMANLIVAQMLFLEAENPEKDIYLYINSPGGVITAGMSIYDTMQFIKPDVS
                     TICMGQAASMGAFLLTAGAKGKRFCLPNSRVMIHQPLGGYQGQATDIEIHAREILKVK
                     GRMNELMALHTGQSLEQIERDTERDRFLSAPEAVEYGLVDSILTHRN"
     gene            57452..58726
                     /gene="clpX"
                     /locus_tag="IRB70_000278"
     CDS             57452..58726
                     /gene="clpX"
                     /locus_tag="IRB70_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001396736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATP-binding subunit ClpX"
                     /protein_id="HBC0630238.1"
                     /translation="MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLC
                     NDIIREEIKEVAPHRERSALPTPHEIRNHLDDYVIGQEQAKKVLAVAVYNHYKRLRNG
                     DTSNGVELGKSNILLIGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
                     IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGT
                     VAAVPPQGGRKHPQQEFLQVDTSKILFICGGAFAGLDKVISHRVETGSGIGFGATVKA
                     KSDKASEGELLAQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEALIQILKEPKNALT
                     KQYQALFNLEGVDLEFRDEALDAIAKKAMARKTGARGLRSIVEAALLDTMYDLPSMED
                     VEKVVIDESVIDGQSKPLLIYGKPEAQQASGE"
     gene            58914..61268
                     /gene="lon"
                     /locus_tag="IRB70_000279"
     CDS             58914..61268
                     /gene="lon"
                     /locus_tag="IRB70_000279"
                     /EC_number="3.4.21.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001469947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endopeptidase La"
                     /protein_id="HBC0630239.1"
                     /translation="MNPERSERIEIPVLPLRDVVVYPHMVIPLFVGREKSIRCLEAAM
                     DHDKKIMLVAQKEASTDEPGVNDLFTVGTVASILQMLKLPDGTVKVLVEGLQRARISA
                     LSDNGEHFSAKAEYLESPTIDEREQEVLVRTAISQFEGYIKLNKKIPPEVLTSLNSID
                     DPARLADTIAAHMPLKLADKQSVLEMSDVNERLEYLMAMMESEIDLLQVEKRIRNRVK
                     KQMEKSQREYYLNEQMKAIQKELGEMDDAPDENEALKRKIDAAKMPKEAKEKAEAELQ
                     KLKMMSPMSAEATVVRGYIDWMVQVPWNARSKVKKDLRQAQEILDTDHYGLERVKDRI
                     LEYLAVQSRVNKIKGPILCLVGPPGVGKTSLGQSIAKATGRKYVRMALGGVRDEAEIR
                     GHRRTYIGSMPGKLIQKMAKVGVKNPLFLLDEIDKMSSDMRGDPASALLEVLDPEQNV
                     AFSDHYLEVDYDLSDVMFVATSNSMNIPAPLLDRMEVIRLSGYTEDEKLNIAKRHLLP
                     KQIERNALKKGELTVDDSAIIGIIRYYTREAGVRGLEREISKLCRKAVKQLLLDKSLK
                     HIEINGDNLHDYLGVQRFDYGRADNENRVGQVTGLAWTEVGGDLLTIETACVPGKGKL
                     TYTGSLGEVMQESIQAALTVVRARAEKLGINPDFYEKRDIHVHVPEGATPKDGPSAGI
                     AMCTALVSCLTGNPVRADVAMTGEITLRGQVLPIGGLKEKLLAAHRGGIKTVLIPFEN
                     KRDLEEIPDNVIADLDIHPVKRIEEVLTLALQNEPSGMQVVTAK"
     gene            61477..61749
                     /gene="hupB"
                     /locus_tag="IRB70_000280"
     CDS             61477..61749
                     /gene="hupB"
                     /locus_tag="IRB70_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-beta"
                     /protein_id="HBC0630240.1"
                     /translation="MNKSQLIDKIAAGADISKAAAGRALDAIIASVTESLKEGDDVAL
                     VGFGTFAVKERAARTGRNPQTGKEITIAAAKVPSFRAGKALKDAVN"
     gene            61941..63812
                     /gene="ppiD"
                     /locus_tag="IRB70_000281"
     CDS             61941..63812
                     /gene="ppiD"
                     /locus_tag="IRB70_000281"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBC0630241.1"
                     /translation="MMDSLRTAANSLVLKIIFGIIIVSFILTGVSGYLIGGGNNYAAK
                     VNDQEISRGQFENAFNSERNRMQQQLGDQYSELAANEGYMKTLRQQVLNRLIDEALLD
                     QYARELKLGISDEQVKQAIFATPAFQVDGKFDNSRYNGILNQMGMTADQYAQALRNQL
                     TTQQLINGVAGTDFMLKGETDELAALVAQQRVVREATIDVNALAAKQPVTEQEIASYY
                     EQNKNNFMTPEQFRVSYIKLDAATMQQPVSDADIQSYYDQHQDQFTQPQRTRYSIIQT
                     KTEDEAKAVLDELNKGGDFAALAKEKSADIISARNGGDMGWLEDATIPDELKNAGLKE
                     KGQLSGVIKSSVGFLIVRLDDIQPAKVKSLDEVRDDVAAKVKHEKALDAYYALQQKVS
                     DAASNDTESLAGAEQAAGVKATQTGWFSKDNLPEELNFKPVADAIFNGGLVGENGAPG
                     INSDIITVDGDRAFVLRISEHKPEAVKPLADVQEQVKALVQHNKAEQQAKVDAEKLLV
                     DLKAGKGAEAMQAAGLKFGEPKTLSRSGRDPISQAAFALPLPAKDKPSYGMATDMQGN
                     VVLLALDEVKQGSMPEDQKKAMVQGITQNNAQIVFEALMSNLRKEAKIKIGDALEQQ"
     gene            63963..64334
                     /locus_tag="IRB70_000282"
     CDS             63963..64334
                     /locus_tag="IRB70_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBC0630242.1"
                     /translation="MKHGIKALLITLSLACAGMSHSALAAAPAAKPTTVETKAEAPAA
                     QSKAAVPAKASDEEGTRVSINNASAEELARAMNGVGLKKAQAIVSYREEYGPFKTVED
                     LKQVPGMGNSLVERNLAVLTL"
     gene            64440..64838
                     /gene="fadM"
                     /locus_tag="IRB70_000283"
     CDS             64440..64838
                     /gene="fadM"
                     /locus_tag="IRB70_000283"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain acyl-CoA thioesterase FadM"
                     /protein_id="HBC0630243.1"
                     /translation="MQTQIKVRGYHLDVYQHVNNARYLEFLEEARWDGLENSDSFQWM
                     TAHNIAFVVVNININYRRPAVLSDLLTITSQLQQLNGKSGILSQVITLEPEGQVVADA
                     LITFVCIDLKTQKALALEGELREKLEQMVK"
     gene            complement(64890..65585)
                     /gene="queC"
                     /locus_tag="IRB70_000284"
     CDS             complement(64890..65585)
                     /gene="queC"
                     /locus_tag="IRB70_000284"
                     /EC_number="6.3.4.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine synthase QueC"
                     /protein_id="HBC0630244.1"
                     /translation="MKRAVVVFSGGQDSTTCLVQALQQYDEVHCVTFDYGQRHRAEID
                     VARELALKLGARAHKVLDVTLLNELAVSSLTRDSIPVPDYEPEADGIPNTFVPGRNIL
                     FLTLAAIYAYQVKAEAVITGVCETDFSGYPDCRDEFVKALNHAVSLGMAKDIRFETPL
                     MWIDKAETWALADYYGKLDLVRNETLTCYNGIKGDGCGHCAACNLRANGLNHYLADKP
                     TVMAAMKQKTGLN"
     gene            complement(65650..67350)
                     /locus_tag="IRB70_000285"
     CDS             complement(65650..67350)
                     /locus_tag="IRB70_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SgrR family transcriptional regulator"
                     /protein_id="HBC0630245.1"
                     /translation="MRLLNRLNQYQRLWQPSAGKPQTVTVSELAERCFCSERHVRTLL
                     RQAQEAGWLEWQAQSGRGKRGQLRFLVTPESLRNAMMEQALETGKQQDVLELAQLAPG
                     ELRTLLQPFMGGQWQNDTPTLRIPYYRPLEPLQPGFLPGRAEQHLAGQIFSGLTRFDN
                     NTQRPIGDLAHHWETSTDGLRWDFYLRSTLHWHNGDAVKASHLHQRLLMLLQLPAVDQ
                     LFISVKRIEVTHPQCLTFFLHRPDYWLAHRLASYCSHLAHPQFPLIGTGPFRLTQFTA
                     ELVRLESHDYYHLRHPLLKAVEYWITPPLFEKDLGTSCRHPVQITIGKPEELQRVSQV
                     SSGISLGFCYLTLRKSPRLSLWQARKVISIIHQSGLLQTLEVGENLITASHALLPGWT
                     IPQWQVPDEVKLPKTLTLVYHLPIELHTMAERLQATLAAEGCELTIIFHNAKNWDDTT
                     LLAHADLMMGDRLIGEAPEYTLEQWLRCDPLWPHVFDAPAYAHLQSTLDAVQVMPDEE
                     NRFNALKAVFSQLMADATLTPLFNYHYRISAPPGVNGVRLTPRGWFEFTEAWLPAPSQ
                     "
     gene            67450..68268
                     /gene="cof"
                     /locus_tag="IRB70_000286"
     CDS             67450..68268
                     /gene="cof"
                     /locus_tag="IRB70_000286"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HMP-PP phosphatase"
                     /protein_id="HBC0630246.1"
                     /translation="MARLAAFDMDGTLLMPDHHLGEKTLSTLARLRERDITLTFATGR
                     HALEMQHILGALSLDAYLITGNGTRVHSLEGELLHRDDLPADVAELVLYQQWDTRASM
                     HIFNDDGWFTGKEIPALLQAFVYSGFRYQIIDVKKMPLGSVTKICFCGDHDDLTRLQI
                     QLYEALGERAHLCFSATDCLEVLPVGCNKGAALTVLTQHLGLSLRDCMAFGDAMNDRE
                     MLGSVGSGFIMGNAMPQLRAELPHLPVIGHCRNQAVSHYLTHWLDYPHLPYSPE"
     gene            68421..68879
                     /gene="decR"
                     /locus_tag="IRB70_000287"
     CDS             68421..68879
                     /gene="decR"
                     /locus_tag="IRB70_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DecR"
                     /protein_id="HBC0630247.1"
                     /translation="MLDKIDRKLLALLQQDCTLSLQALAEAVNLTTTPCWKRLKRLED
                     DGILIGKVALLDPEKIGLGLTAFVLIKTQHHSSEWYCRFVTVVTEMPEVLGFWRMAGE
                     YDYLMRVQVADMKRYDEFYKRLVNSVPGLSDVTSSFAMEQIKYTTSLPIE"
     gene            68909..70681
                     /locus_tag="IRB70_000288"
     CDS             68909..70681
                     /locus_tag="IRB70_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdA family multidrug ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HBC0630248.1"
                     /translation="MRLFAQLSWYFRREWRRYLGAVALLVIIAMLQLVPPKVVGIVVD
                     GVTEQHFTTGQILMWIATMVLIAVVVYLLRYVWRVLLFGASYQLAVELREDYYRQLSR
                     QHPEFYLRHRTGDLMARATNDVDRVVFAAGEGVLTLVDSLVMGCAVLIMMSTQISWQL
                     TLFALLPMPVMAIMIKRNGDALHERFKLAQAAFSSLNDRTQESLTSIRMIKAFGLEDR
                     QSALFAADAEDTGKKNMRVARIDARFDPTIYIAIGMANLLAIGGGSWMVVQGSLTLGQ
                     LTSFMMYLGLMIWPMLALAWMFNIVERGSAAYSRIRTMLAEAPVVIDGSDKVPEGRGE
                     LDVNIRQFTYPQTDHPALENVNFALKPGQMVGICGPTGSGKSTLLSLIQRHFDVSEGD
                     IRFHDIPLTKLQLDSWRSRLAVVSQTPFLFSDTVANNIALGCPNATQQEIEHVARLAS
                     VHDDILRLPQGYDTEVGERGVMLSGGQKQRISIARALLVNAEILILDDALSAVDGRTE
                     HQILHNLRQWGQGRTVIISAHRLSALTEASEIIVMQHGHIAQRGNHDVLAQQSGWYRD
                     MYRYQQLEAALDDAPENREEAVDA"
     gene            70674..72455
                     /locus_tag="IRB70_000289"
     CDS             70674..72455
                     /locus_tag="IRB70_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SmdB family multidrug efflux ABC transporter
                     permease/ATP-binding protein"
                     /protein_id="HBC0630249.1"
                     /translation="MRSFSQLWPTLKRLLAYGSPWRKPLGIAVLMMWVAAAAEVSGPL
                     LISYFIDNMVAKNNLPLKVVAGLAAAYVGLQLFAAGLHYAQSLLFNRAAVGVVQQLRT
                     DVMDAALRQPLSEFDTQPVGQVISRVTNDTEVIRDLYVTVVATVLRSAALVGAMLVAM
                     FSLDWRMALVAIMIFPVVLVVMVIYQRYSTPIVRRVRAYLADINDGFNEIINGMSVIQ
                     QFRQQARFGERMGEASRSHYMARMQTLRLDGFLLRPLLSLFSSLILCGLLMLFGFSVS
                     GTIEVGVLYAFISYLGRLNEPLIELTTQQAMLQQAVVAGERVFELMDGPRQQYGNDDR
                     PLQSGTIEVDNVSFAYRDDNMVLKNINLSVPSRNFVALVGHTGSGKSTLASLLMGYYP
                     LTEGEIRLDGRPLSSLSHSALRQGVAMVQQDPVVLADTFLANVTLGRDISEERVWQAL
                     ETVQLAELARSMSDGIYTPLGEQGNNLSVGQKQLLALARVLVETPQILILDEATASID
                     SGTEQAIQHALAAVREHTTLVVIAHRLSTIVDADTILVLHRGQAVEQGTHQQLLAAQG
                     RYWQMYQLQLAGEELAASVREEESLSA"
     gene            72636..72974
                     /gene="glnK"
                     /locus_tag="IRB70_000290"
     CDS             72636..72974
                     /gene="glnK"
                     /locus_tag="IRB70_000290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBC0630250.1"
                     /translation="MKLVTVIIKPFKLEDVREALSSIGIQGLTVTEVKGFGRQKGHAE
                     LYRGAEYSVNFLPKVKIDVAIADDQLDEVIDIVSKAAYTGKIGDGKIFVAELQRVIRI
                     RTGEADEAAL"
     gene            73004..74290
                     /gene="amtB"
                     /locus_tag="IRB70_000291"
     CDS             73004..74290
                     /gene="amtB"
                     /locus_tag="IRB70_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter AmtB"
                     /protein_id="HBC0630251.1"
                     /translation="MKIATIKTGLASLAMLPGLVMAAPAVADKADNAFMMICTALVLF
                     MTIPGIALFYGGLIRGKNVLSMLTQVTVTFALVCILWVVYGYSLAFGEGNNFFGNINW
                     LMLKNIELTAVMGSIYQYIHVAFQGSFACITVGLIVGALAERIRFSAVLIFVVVWLTL
                     SYIPIAHMVWGGGLLASHGALDFAGGTVVHINAAIAGLVGAYLIGKRVGFGKEAFKPH
                     NLPMVFTGTAILYIGWFGFNAGSAGTANEIAALAFVNTVVATAAAILGWIFGEWALRG
                     KPSLLGACSGAIAGLVGVTPACGYIGVGGALIIGVVAGLAGLWGVTMLKRLLRVDDPC
                     DVFGVHGVCGIVGCIMTGIFAASSLGGVGFAEGVTMGHQLLVQLESIAITIVWSGVVA
                     FIGYKLADLTVGLRVPEEQEREGLDVNSHGENAYNA"
     gene            complement(74339..75199)
                     /gene="tesB"
                     /locus_tag="IRB70_000292"
     CDS             complement(74339..75199)
                     /gene="tesB"
                     /locus_tag="IRB70_000292"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase II"
                     /protein_id="HBC0630252.1"
                     /translation="MSQALKNLLTLLNLEKIEEGLFRGQSEDLGLRQVFGGQVVGQAL
                     YAAKETVPEERLVHSFHSYFLRPGDSKKPIIYDVETLRDGNSFSARRVAAIQNGKPIF
                     YMTASFQAPEAGFEHQKTMPSAPAPDGLPSETQIAQSLAHLLPPVLKDKFICDRPLEV
                     RPVEFHNPLKGHVAEPHRQVWIRANGSVPDDLRVHQYLLGYASDLNFLPVALQPHGIG
                     FLEPGIQIATIDHSMWFHRPFNLNEWLLYSVESTSASSARGFVRGEFYTQDGVLVAST
                     VQEGVMRNHN"
     gene            75417..75989
                     /locus_tag="IRB70_000293"
     CDS             75417..75989
                     /locus_tag="IRB70_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaY family lipoprotein"
                     /protein_id="HBC0630253.1"
                     /translation="MKLVHMASGLAVAIALAACADKSADIQTPAPAANTSISATQQPA
                     IQQPNVSGTVWIRQKVALPPDAVLTVTLSDASLADAPSKVLAQKAVRTEGKQSPFSFV
                     LPFNPADVQPNARILLSAAITVNDKLVFITDTVQPVINQGGTKADLTLVPVQQTAVPV
                     QASGGATTTVPSTSPTQVNPSSAVPAPTQY"
     gene            complement(76020..76331)
                     /locus_tag="IRB70_000294"
     CDS             complement(76020..76331)
                     /locus_tag="IRB70_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MGMT family protein"
                     /protein_id="HBC0630254.1"
                     /translation="MEKEDSFPQRVWQIVAAIPEGYVTTYGDVAKLAGSPRAARQVGG
                     VLKRLPEGSTLPWHRVVNRHGTISLTGPDLQRQRQALLAEGVMVSGSGQIDLQRYRWN
                     Y"
     gene            76494..76590
                     /gene="ffs"
                     /locus_tag="IRB70_000295"
     ncRNA           76494..76590
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="IRB70_000295"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            76710..77063
                     /locus_tag="IRB70_000296"
     CDS             76710..77063
                     /locus_tag="IRB70_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1428 domain-containing protein"
                     /protein_id="HBC0630255.1"
                     /translation="MKYVDGFVVAVPADKKDAYREMAAKAAPLFKEFGALRIVECWAS
                     DVPDGKVTDFRMAVKAEENEEVVFSWIEYPSKEVRDAANQKMMSDPRMKEFGESMPFD
                     GKRMIYGGFESIIDE"
     gene            complement(77105..78655)
                     /gene="pdeB"
                     /locus_tag="IRB70_000297"
     CDS             complement(77105..78655)
                     /gene="pdeB"
                     /locus_tag="IRB70_000297"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeB"
                     /protein_id="HBC0630256.1"
                     /translation="MRTRHLVGLISGVLILSVLLPVGLSIWLAHQQVETSFIEELNTY
                     SSRVAIRANKVATQGKDALQELERWQGAACSAAHLMEMRRVSYSYRYIQEVVYIDNNV
                     PLCSSLEHESPPDAFPEPGKISKDGYRVWLTSHNDLGIIRYMVAMGTAHYVVMIDPAS
                     FIDVIPYSSWQIDAAIIGNAHNVVITSSDEIAQGIITRLQKTPGEHIENNGIIYDILP
                     LPEMNISIITWASTKMLQKGWHRQVFIWLPLGLVIGLLAAMFVLRILRRIQSPHHRLQ
                     DAIENRDICVHYQPIVSLANGKIVGAEALARWPQTDGSWLSPDSFIPLAQQTGLSEPL
                     TLLIIKSVFEDMGDWLRQHPQQHISINLESTVLTSEKIPQLLREMINHYQVNPRQIAL
                     ELTEREFADPKTSAPIISRYREAGHEIYLDDFGTGYSSLSYLQDLDVDILKIDKSFVD
                     ALEYKNVTPHIIEMAKTLKLKMVAEGIETSKQEEWLRQHGVHYGQGWLYSKALPKEDF
                     LRWAEQHL"
     gene            complement(78819..79289)
                     /locus_tag="IRB70_000298"
     CDS             complement(78819..79289)
                     /locus_tag="IRB70_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaC family protein"
                     /protein_id="HBC0630257.1"
                     /translation="MTEIQRLLTETIESLNTREKRDNKPRFSISFIRKHPGLFIGMYV
                     AFFATLAVMLQSETLSGSVWLLVVLFILLNGFFFFDVYPRYRYEDIDVLDFRVCYNGE
                     WYNTRFVPAALVEAILNSPRVADVHKEQLQKMLVRKGELSFYDIFTLARAESTS"
     gene            complement(79405..79956)
                     /gene="maa"
                     /locus_tag="IRB70_000299"
     CDS             complement(79405..79956)
                     /gene="maa"
                     /locus_tag="IRB70_000299"
                     /EC_number="2.3.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose O-acetyltransferase"
                     /protein_id="HBC0630258.1"
                     /translation="MSTEKEKMIAGELYRSADETLSRDRLRARQLIHRYNHSLAEEHT
                     LRQQILAELFGQVTEAYIEPTFRCDYGYNIFLGNNFFANFDCVMLDVCPIRIGDNCML
                     APGVHIYTATHPIDPVARNSGAELGKPVTIGNNVWIGGRAIINPGVTIGDNVVVASGA
                     VVTKDVPDNVVVGGNPARIIKKL"
     gene            complement(80128..80346)
                     /gene="hha"
                     /locus_tag="IRB70_000300"
     CDS             complement(80128..80346)
                     /gene="hha"
                     /locus_tag="IRB70_000300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin expression modulator Hha"
                     /protein_id="HBC0630259.1"
                     /translation="MSEKPLTKTDYLMRLRRCQTIDTLERVIEKNKYELSDNELAVFY
                     SAADHRLAELTMNKLYDKIPSSVWKFIR"
     gene            complement(80372..80746)
                     /gene="tomB"
                     /locus_tag="IRB70_000301"
     CDS             complement(80372..80746)
                     /gene="tomB"
                     /locus_tag="IRB70_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hha toxicity modulator TomB"
                     /protein_id="HBC0630260.1"
                     /translation="MDEYSPKRHDIAQLKFLCETLYHDCLANLEESNHGWVNDPTSAI
                     NLQLNELIEHIATFALNYKIKYNEDNKLIEQIDEYLDDTFMLFSSYGINMQDLQKWRK
                     SGNRLFRCFVNATKENPASLSC"
     gene            complement(81292..84441)
                     /locus_tag="IRB70_000302"
     CDS             complement(81292..84441)
                     /locus_tag="IRB70_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HBC0630261.1"
                     /translation="MPNFFIDRPIFAWVIAIIIMLAGGLAILKLPVAQYPTIAPPAVT
                     ISASYPGADAKTVQDTVTQVIEQNMNGIDNLMYMSSNSDSTGTVQITLTFESGTDADI
                     AQVQVQNKLQLAMPLLPQEVQQQGVSVEKSSSSFLMVVGVINTDGTMTQEDISDYVAA
                     NMKDAISRTSGVGDVQLFGSQYAMRIWMNPNELNKFQLTPVDVITAIKAQNAQVAAGQ
                     LGGTPPVKGQQLNASIIAQTRLTSTEEFGKILLKVNQDGSRVLLRDVAKIELGGENYD
                     IIAEFNGQPASGLGIKLATGANALDTAAAIRAELAKMEPFFPSGLKIVYPYDTTPFVK
                     ISIHEVVKTLVEAIILVFLVMYLFLQNFRATLIPTIAVPVVLLGTFAVLAAFGFSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMAEEGLPPKEATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATMLKPIAKGDHGEG
                     KKGFFGWFNRMFEKSTHHYTDSVGGILRSTGRYLVLYLIIVVGMAYLFVRLPSSFLPD
                     EDQGVFMTMVQLPAGATQERTQKVLNEVTHYYLTKEKNNVESVFAVNGFGFAGRGQNT
                     GIAFVSLKDWADRPGEENKVEAITMRATRAFSQIKDAMVFAFNLPAIVELGTATGFDF
                     ELIDQAGLGHEKLTQARNQLLAEAAKHPDMLTSVRPNGLEDTPQFKIDIDQEKAQALG
                     VSINDINTTLGAAWGGSYVNDFIDRGRVKKVYVMSEAKYRMLPDDIGDWYVRAADGQM
                     VPFSAFSSSRWEYGSPRLERYNGLPSMEILGQAAPGKSTGEAMELMEQLASKLPTGVG
                     YDWTGMSYQERLSGNQAPSLYAISLIVVFLCLAALYESWSIPFSVMLVVPLGVIGALL
                     AATFRGLTNDVYFQVGLLTTIGLSAKNAILIVEFAKDLMDKEGKGLIEATLDAVRMRL
                     RPILMTSLAFILGVMPLVISTGAGSGAQNAVGTGVMGGMVTATVLAIFFVPVFFVVVR
                     RRFSRKNEDIEHSHTVDHH"
     gene            complement(84464..85657)
                     /gene="acrA"
                     /locus_tag="IRB70_000303"
     CDS             complement(84464..85657)
                     /gene="acrA"
                     /locus_tag="IRB70_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrA"
                     /protein_id="HBC0630262.1"
                     /translation="MNKNRGFTPLAVVLMLSGSLALTGCDDKQAQQGGQQMPAVGVVT
                     VKTEPLQITTELPGRTSAYRIAEVRPQVSGIILKRNFKEGSDIEAGVSLYQIDPATYQ
                     AAYDSAKGDLAKAQAAANIAQLTVNRYQKLLGTQYISKQEYDQALADAQQANAAVTAA
                     KAAVETARINLAYTKVTSPISGRIGKSNVTEGALVQNGQATALATVQQLDPIYVDVTQ
                     SSNDFLRLKQELANGTLKQENGKAKVSLITSDGIKFPQDGTLEFSDVTVDQTTGSITL
                     RAIFPNPDHTLLPGMFVRARLEEGLNPNAILVPQQGVTRTPRGDATVLVVGADDKVET
                     RPIVASQAIGDKWLVTEGLKAGDRVVISGLQKVRPGVQVKAQEVTADNNQQAASGAQP
                     EQSKS"
     gene            85799..86446
                     /gene="acrR"
                     /locus_tag="IRB70_000304"
     CDS             85799..86446
                     /gene="acrR"
                     /locus_tag="IRB70_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrR"
                     /protein_id="HBC0630263.1"
                     /translation="MARKTKQEAQETRQHILDVALRLFSQQGVSSTSLGEIAKAAGVT
                     RGAIYWHFKDKSDLFSEIWELSESNIGELELEYQAKFPGDPLSVLREILIHVLESTVT
                     EERRRLLMEIIFYKCEFVGEMAVVQQAQRNLCLESYDRIEQTLKHCIEAKMLPADLMT
                     RRAAIIMRGYISGLMENWLFAPQSFDLKKEARDYVAILLEMYLLCPTLRNPATNE"
     gene            86574..89936
                     /gene="mscK"
                     /locus_tag="IRB70_000305"
     CDS             86574..89936
                     /gene="mscK"
                     /locus_tag="IRB70_000305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive channel MscK"
                     /protein_id="HBC0630264.1"
                     /translation="MTMFQYYKRSRHFVFSAFIAFVFVLLCQNTAFARASSNGDLPTK
                     ADLQAQLDSLNKQKDLSAQDKLVQQDLTDTLATLDKIDRVKEETVQLRQKVAEAPEKM
                     RQATAALTALSDVDNDEETRKILSTLSLRQLETRVAQALDDLQNAQNDLASYNSQLVS
                     LQTQPERVQNAMYNASQQLQQIRSRLDGTDVGETALRPSQKVLMQAQQALLNAEIDQQ
                     RKSLEGNTVLQDTLQKQRDYVTANSARLEHQLQLLQEAVNSKRLTLTEKTAQEAVSPD
                     EAARIQANPLVKQELEINQQLSQRLITATENGNQLMQQNIKVKNWLERALQSERNIKE
                     QIAVLKGSLLLSRILYQQQQTLPSADELENMTNRIADLRLEQFEVNQQRDALFQSDAF
                     VNKLEEGHTNEVNSEVHDALLQVVDMRRELLDQLNKQLGNQLMMAINLQINQQQLMSV
                     SKNLKSILTQQIFWVNSNRPMDWDWIKAFPQSLKDEFKSMKITVNWEKAWPAVFIAFL
                     AGLPLLLIAGLIHWRLGWLKAYQQKLASAVGSLRNDSQLNTPKAILIDLIRALPVCLI
                     ILAVGLILLTMQLNISELLWSFSKKLAIFWLVFGLCWKVLEKNGVAVRHFGMPEQQTS
                     HWRRQIVRISLALLPIHFWSVVAELSPLHLMDDVLGQAMIFFNLLLIAFLVWPMCRES
                     WRDKESHTMRLVTITVLSIIPIALMVLTATGYFYTTLRLSGRWIETVYLVIIWNLLYQ
                     TVLRGLSVAARRIAWRRALARRQNLVKEGAEGAEPPEEPTIALEQVNQQTLRITMLLM
                     FALFGVMFWAIWSDLITVFSYLDSITLWHYNGTEAGAAVVKNVTMGSLLFAIIASMVA
                     WALIRNLPGLLEVLVLSRLNMRQGASYAITTILNYIIIAVGAMTVFGSLGVSWDKLQW
                     LAAALSVGLGFGLQEIFGNFVSGLIILFERPVRIGDTVTIGSFSGTVSKIRIRATTIT
                     DFDRKEVIIPNKAFVTERLINWSLTDTTTRLVIRLGVAYGSDLEKVRKVLLKAATEHP
                     RVMHEPMPEVFFTAFGASTLDHELRLYVRELRDRSRTVDELNRTIDQLCRENDINIAF
                     NQLEVHLHNEKGDEVTEVKRDYKGDDPTPAVG"
     gene            complement(89975..90139)
                     /gene="rsmS"
                     /locus_tag="IRB70_000306"
     CDS             complement(89975..90139)
                     /gene="rsmS"
                     /locus_tag="IRB70_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pleiotropic regulatory protein RsmS"
                     /protein_id="HBC0630265.1"
                     /translation="MSLENAPDDVKLAVDLIVLLEENQIPARTVLRALDIVKRDYEKK
                     LQSDETSQSE"
     gene            complement(90153..90680)
                     /gene="priC"
                     /locus_tag="IRB70_000307"
     CDS             complement(90153..90680)
                     /gene="priC"
                     /locus_tag="IRB70_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N''"
                     /protein_id="HBC0630266.1"
                     /translation="MKTTLLLEKLEGQLATLRQRCAPVAQFATLSARFDRHLFQTRAT
                     TLQACLDEAGDNLAALRHAVEQQQLPQAAWLAEHLAAQLEAIAREATAWSLREWDSAP
                     PKIARWQRKRIQHQDFERRLREMVAERRARLARVTDLVEQQTLHREVEAYEARLARCR
                     HALEKIENRLARLTR"
     gene            90750..91127
                     /locus_tag="IRB70_000308"
     CDS             90750..91127
                     /locus_tag="IRB70_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF454 family protein"
                     /protein_id="HBC0630267.1"
                     /translation="MQRIILIIIGWLAVVLGTLGVVLPVLPTTPFILLAAWCFARSSP
                     RFHAWLLYRSWFGSYLRFWQKHHAMPRGVKPRAIMLILLTFAISLWFVQMPWVRIMLL
                     VILACLLFYMWRIPVIDEKQEKH"
     gene            91280..91831
                     /gene="apt"
                     /locus_tag="IRB70_000309"
     CDS             91280..91831
                     /gene="apt"
                     /locus_tag="IRB70_000309"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBC0630268.1"
                     /translation="MTATAQQLEYLKNSIKSIQDYPKPGILFRDVTSLLEDPKAYALS
                     IDLLVERYKNAGITKVVGTEARGFLFGAPVALGLGVGFVPVRKPGKLPRETISETYDL
                     EYGTDQLEIHVDAIKPGDKVLVVDDLLATGGTIEATVKLIRRLGGEVADAAFIINLFD
                     LGGEQRLEKQGITSYSLVPFPGH"
     gene            91960..93891
                     /gene="dnaX"
                     /locus_tag="IRB70_000310"
     CDS             91960..93891
                     /gene="dnaX"
                     /locus_tag="IRB70_000310"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBC0630269.1"
                     /translation="MSYQVLARKWRPQTFADVVGQEHVLTALANGLSLGRIHHAYLFS
                     GTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRTKVE
                     DTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLLATTDPQ
                     KLPVTILSRCLQFHLKALDVEQIRHQLEHILNEEHIAHEPRALQLLARAAEGSLRDAL
                     SLTDQAIASGDGQVSTQAVSAMLGTLDDDQALSLVEAMVEANGERVMALINEAAARGI
                     EWEALLVEMLGLLHRIAMVQLSPAALGNDMAAIELRMRELARTIPPTDIQLYYQTLLI
                     GRKELPYAPDRRMGVEMTLLRALAFHPRMPLPEPEVPRQSFAPVAPTAVMTPTQVPPQ
                     PQSAPQQAPTVPLPETTSQVLAARKQLQRVQGATKAKKSEPAAATRARPVNNAALERL
                     ASVTDRVQARPVPSALEKAPAKKEAYRWKATTPVMQQKEVVATPKALKKALEHEKTPE
                     LAAKLAAEAIERDPWAAQVSQLSLPKLVEQVALNAWKEESDNAVCLHLRSSQRHLNNR
                     GAQQKLAEALSTLKGSTVELTIVEDDNPAVRTPLEWRQAIYEEKLAQARESIIADNNI
                     QTLRRFFDAELDEESIRPI"
     misc_feature    93224..93288
                     /gene="dnaX"
                     /locus_tag="IRB70_000310"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00382"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="DnaX frameshifting element; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00382"
     gene            93944..94273
                     /locus_tag="IRB70_000311"
     CDS             93944..94273
                     /locus_tag="IRB70_000311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001364632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBC0630270.1"
                     /translation="MFGKGGLGNLMKQAQQMQEKMQKMQEEIAQLEVTGESGAGLVKV
                     TINGAHNCRRVEIDPSLLEDDKEMLEDLVAAAFNDAARRIEETQKEKMASVSSGMQLP
                     PGFKMPF"
     gene            94273..94878
                     /gene="recR"
                     /locus_tag="IRB70_000312"
     CDS             94273..94878
                     /gene="recR"
                     /locus_tag="IRB70_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBC0630271.1"
                     /translation="MQTSPLLTQLMEALRCLPGVGPKSAQRMAFTLLQRDRSGGMRLA
                     QALTRAMSEIGHCADCRTFTEQEVCNICSNPRRQENGQICVVESPADIYAIEQTGQFS
                     GRYFVLMGHLSPLDGIGPDDIGLDRLEQRLAEEKITEVILATNPTVEGEATANYIAEL
                     CAQYDVEASRIAHGVPVGGELEMVDGTTLSHSLAGRHKIRF"
     gene            94988..96862
                     /gene="htpG"
                     /locus_tag="IRB70_000313"
     CDS             94988..96862
                     /gene="htpG"
                     /locus_tag="IRB70_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003903109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HtpG"
                     /protein_id="HBC0630272.1"
                     /translation="MKGQETRGFQSEVKQLLHLMIHSLYSNKEIFLRELISNASDAAD
                     KLRFRALSNPDLYEGDGELRVRVSFDKDKRTLTISDNGVGMTRDEVIDHLGTIAKSGT
                     KSFLESLGSDQAKDSQLIGQFGVGFYSAFIVADKVTVRTRAAGEKPENGVFWESAGEG
                     EYTVADITKEDRGTEITLHLREGEDEFLDDWRVRSIISKYSDHIALPVEIEKREEKDG
                     ETVISWEKINKAQALWTRNKSEITDEEYKEFYKHIAHDFNDPLTWSHNRVEGKQEYTS
                     LLYIPSQAPWDMRNRDHKHGLKLYVQRVFIMDDAEQFMPNYLRFVRGLIDSSDLPLNV
                     SREILQDSTVTRNLRNALTKRVLQMLEKLAKDDAEKYQTFWQQFGLVLKEGPAEDFAN
                     QEAIAKLLRFASTHTDSSAQTVSLEDYVSRMKEGQEKIYYITADSYAAAKSSPHLELL
                     RKKGIEVLLLSDRIDEWMMNYLTEFDGKPFQSVSKVDESLEKLADEVDESAKEAEKAL
                     TPFIDRVKALLGERVKDVRLTHRLTDTPAIVSTDADEMSTQMAKLFAAAGQKVPEVKY
                     IFELNPDHVLVKRAADTEDEAKFSEWVELLLDQALLAERGTLEDPNLFIRRMNQLLVS
                     "
     gene            97043..97687
                     /gene="adk"
                     /locus_tag="IRB70_000314"
     CDS             97043..97687
                     /gene="adk"
                     /locus_tag="IRB70_000314"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007706188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBC0630273.1"
                     /translation="MRIILLGAPGAGKGTQAQFIMEKYGIPQISTGDMLRAAVKSGSE
                     LGKQAKDIMDAGKLVTDELVIALVKERIAQEDCRNGFLLDGFPRTIPQADAMKEAGIN
                     VDYVLEFDVPDELIVDRIVGRRVHAPSGRVYHVKFNPPKVEGKDDVTGEELTTRKDDQ
                     EETVRKRLVEYHQMTAPLIGYYSKEAEAGNTKYAKVDGTKPVAEVRADLEKILG"
     gene            97819..98781
                     /gene="hemH"
                     /locus_tag="IRB70_000315"
     CDS             97819..98781
                     /gene="hemH"
                     /locus_tag="IRB70_000315"
                     /EC_number="4.99.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrochelatase"
                     /protein_id="HBC0630274.1"
                     /translation="MRQTKTGILLANLGTPDAPTPEAVKRYLKQFLSDRRVVDTSRLL
                     WWPLLRGVILPLRSPRVAKLYASVWMEGGSPLMVYSRQQQQALAQRLPETPVALGMSY
                     GSPSLESAVDELLAEHVDHIVVLPLYPQYSCSTVGAVWDELARILARKRSIPGISFIR
                     DYADNHDYINALANSVRASFAKHGEPDLLLLSYHGIPQRYADEGDDYPQRCRTTTREL
                     ASALGMAPEKVMMTFQSRFGREPWLMPYTDETLKMLGEKGVGHIQVMCPGFAADCLET
                     LEEIAEQNREVFLGAGGKKYEYIPALNATPEHIEMMANLVAAYR"
     gene            complement(98778..99737)
                     /gene="aes"
                     /locus_tag="IRB70_000316"
     CDS             complement(98778..99737)
                     /gene="aes"
                     /locus_tag="IRB70_000316"
                     /EC_number="3.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl esterase"
                     /protein_id="HBC0630275.1"
                     /translation="MKPENKLPVLDLISAEMKTVVNTLQPDLPPWPATGTIAEQRQHY
                     TLERRFWNAGAPEMATRAYMVPTKYGQVETRLFCPQPDSPATLFYLHGGGFILGNLDT
                     HDRIMRLLASYSQCTVIGIDYTLSPEACFPQAIEEIVAACCYFHQQAEDYQINMSRIG
                     FAGDSAGAMLALASALWLRDKQIDCGKVAGVLLWYGLYGLRDSVTRRLLGGVWDGLTQ
                     QDLQMYEEAYLSNDADRESPYYCLFNNDLTREVPPCFIAGAEFDPLLDDSRLLYQTLA
                     AHQQPCEFKLYPGTLHAFLHYSRMMKTADEALRDGAQFFTAQL"
     gene            99889..101193
                     /gene="gsk"
                     /locus_tag="IRB70_000317"
     CDS             99889..101193
                     /gene="gsk"
                     /locus_tag="IRB70_000317"
                     /EC_number="2.7.1.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/guanosine kinase"
                     /protein_id="HBC0630276.1"
                     /translation="MKFPGKRKSKHYFPVNARDPLLQQFQPENETSAAWVVGIDQTLV
                     DIEAKVDDEFIERYGLSAGHSLVIEDDVAEALYQELKQKNLITHQFAGGTIGNTMHNY
                     SVLADDRSVLLGVMCSNIEIGSYAYRYLCNTSSRTDLNYLQGVDGPIGRCFTLIGESG
                     ERTFAISPGHMNQLRAESIPEDVIAGASALVLTSYLVRCKPGEPMPEATMKAIEYAKK
                     YNVPVVLTLGTKFVIAENPQWWQQFLKDHVSILAMNEDEAEALTGESDPLLASDKALD
                     WVDLVLCTAGPIGLYMAGFTEDEAKRKTQHPLLPGAIAEFNQYEFSRAMRHKDCQNPL
                     RVYSHIAPYMGGPEKIMNTNGAGDGALAALLHDITANSYHRSNVPNSSKHKFTWLTYS
                     SLAQVCKYANRVSYQVLNQHSPRLTRGLPEREDSLEESYWDR"
     gene            complement(101277..102953)
                     /locus_tag="IRB70_000318"
     CDS             complement(101277..102953)
                     /locus_tag="IRB70_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kef family K(+) transporter"
                     /protein_id="HBC0630277.1"
                     /translation="MHHATPLITTIVGGLVLAFILGMLANKLRISPLVGYLLAGVLAG
                     PFTPGFVADTKLAPELAELGVILLMFGVGLHFSLKDLMAVKAIAIPGAIAQIAVATLL
                     GMALSAVLGWSLMTGIVFGLCLSTASTVVLLRALEERQLIDSQRGQIAIGWLIVEDLV
                     MVLTLVLLPAVAGMMEQGDVGFATLAVDMGITIGKVIAFIAIMMLVGRRLVPWIMARS
                     AATGSRELFTLSVLALALGIAFGAVELFDVSFALGAFFAGMVLNESELSHRAAHDTLP
                     LRDAFAVLFFVSVGMLFDPLILIQQPLAVLATLAIILFGKSLAAFFLVRLFGHSQRTA
                     LTIAASLAQIGEFAFILAGLGMALDLLPQAGQNLVLAGAILSIMLNPVLFALLEKYLA
                     KTETLEEQTLEEAIEEEKQIPVDICNHALLVGYGRVGSLLGEKLLASDIPLVVIETSR
                     TRVDELRERGVRAVLGNAANEEIMQLAHLECAKWLILTIPNGYEAGEIVASARAKNPD
                     IEIIARAHYDDEVAYITERGANQVVMGEREIARTMLELLETPPAGEVVTG"
     gene            complement(103191..104411)
                     /gene="fsr"
                     /locus_tag="IRB70_000319"
     CDS             complement(103191..104411)
                     /gene="fsr"
                     /locus_tag="IRB70_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fosmidomycin MFS transporter"
                     /protein_id="HBC0630278.1"
                     /translation="MAMSEQTQPVAGAAASTTKARTSFGILGAISLSHLLNDMIQSLI
                     LAIYPLLQSEFSLTFMQIGMITLTFQLASSLLQPVVGYWTDKYPMPWSLPIGMCFTLS
                     GLVLLALAGSFGAVLLAAALVGTGSSVFHPESSRVARMASGGRHGLAQSIFQVGGNFG
                     SSLGPLLAAVIIAPYGKGNVAWFVLAALLAIVVLAQISRWYSAQHRMNKGKPKATIIN
                     PLPRNKVVLAVSILLILIFSKYFYMASISSYYTFYLMQKFGLSIQNAQLHLFAFLFAV
                     AAGTVIGGPVGDKIGRKYVIWGSILGVAPFTLILPYASLHWTGVLTVIIGFILASAFS
                     AILVYAQELLPGRIGMVSGFFFGFAFGMGGLGAAVLGLIADHTSIELVYKICAFLPLL
                     GMLTIFLPDNRHKD"
     gene            104629..106281
                     /gene="ushA"
                     /locus_tag="IRB70_000320"
     CDS             104629..106281
                     /gene="ushA"
                     /locus_tag="IRB70_000320"
                     /EC_number="3.1.3.5"
                     /EC_number="3.6.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-sugar
                     hydrolase/5'-nucleotidase"
                     /protein_id="HBC0630279.1"
                     /translation="MKLLQRGVALALLTTFTLASETALAYEQDKTYKITVLHTNDHHG
                     HFWRNEYGEYGLAAQKTLVDGIRKEVAAEGGSVLLLSGGDINTGVPESDLQDAEPDFR
                     GMNLVGYDAMAIGNHEFDNPLTVLRQQEKWAKFPLLSANIYQKSTGERLFKPWALFKR
                     QDLKIAVIGLTTDDTAKIGNPEYFTDIEFRKPADEAKLVIQELQQTEKPDIIIAATHM
                     GHYDNGEHGSNAPGDVEMARALPAGSLAMIVGGHSQDPVCMAAENKKQVDYVPGTPCK
                     PDQQNGIWIVQAHEWGKYVGRADFEFRNGEMKMVNYQLIPVNLKKKVTWEDGKSERVL
                     YTPEIAENQQMISLLSPFQNKGKAQLEVKIGETNGRLEGDRDKVRFVQTNMGRLILAA
                     QMDRTGADFAVMSGGGIRDSIEAGDISYKNVLKVQPFGNVVVYADMTGKEVIDYLTAV
                     AQMKPDSGAYPQFANVSFVAKDGKLNDLKIKGEPVDPAKTYRMATLNFNATGGDGYPR
                     LDNKPGYVNTGFIDAEVLKAYIQKSSPLDVSVYEPKGEVSWQ"
     gene            complement(106318..106797)
                     /gene="ybaK"
                     /locus_tag="IRB70_000321"
     CDS             complement(106318..106797)
                     /gene="ybaK"
                     /locus_tag="IRB70_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase YbaK"
                     /protein_id="HBC0630280.1"
                     /translation="MTPAVKLLEKNKISFQIHTYEHDPAETNFGDEVVKKLGLNPDQV
                     YKTLLVAVNGDMKHLAVAVTPVAGQLDLKKVAKALGAKKVEMADPMVAQRSTGYLVGG
                     ISPLGQKKRLPTIIDTPAQEFATIYVSGGKRGLDIELAASDLAKILDAKFADIARRD"
     gene            complement(107001..107795)
                     /locus_tag="IRB70_000322"
     CDS             complement(107001..107795)
                     /locus_tag="IRB70_000322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraB/GumN family protein"
                     /protein_id="HBC0630281.1"
                     /translation="MDLLYRVKTLWAALRGNHYTWPAIDISLPGNRHFHLLGSIHMGS
                     HDMAPLPTRLLKKLKNADALIVEADVSTSDTPFANLPACEALEERISEEQLQNLQHIS
                     QEMGISTSLFSTQPLWQIAMVLQATQAQKLGLRAEYGIDYQLLQAAKQQHKPVIELEG
                     AENQIAMLLQLPDNGLALLDDTLTHWHTNARLLQQMMSWWLNTPPQNNEITLPNTFSQ
                     SLYDVLMHQRNLAWRDKLRAMPPGRYVVAVGALHLYGEGNLPQMLR"
     gene            107928..108230
                     /locus_tag="IRB70_000323"
     CDS             107928..108230
                     /locus_tag="IRB70_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000057540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBC0630282.1"
                     /translation="MAQKNNIRSFRDAWLADFFVHSTPHRKIPAEIHTTLSRKLDIIN
                     AATSHRDLRSPPGNRYEELSGKLQEYSSIRVNKQYRLIFKWVNGKAEELFLDPHNY"
     gene            108266..108607
                     /locus_tag="IRB70_000324"
     CDS             108266..108607
                     /locus_tag="IRB70_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415016.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HBC0630283.1"
                     /translation="MKQATRKPTTPGDILLYEYLEPLDLKINELAELLHVHRNSVSAL
                     INNNRKLTTEMAFRLAKVFDTTVDFWLNLQAAVDLWEVENNMRTQEELGRIETVAEYL
                     ARREERAKKVA"
     gene            complement(108665..111169)
                     /gene="copA"
                     /locus_tag="IRB70_000325"
     CDS             complement(108665..111169)
                     /gene="copA"
                     /locus_tag="IRB70_000325"
                     /EC_number="7.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-exporting P-type ATPase CopA"
                     /protein_id="HBC0630284.1"
                     /translation="MSQTIDLTLDGLSCGHCVKRVKESLEQRPDVEQADVSVTEAHVT
                     GTASAEQLIETIKQAGYDASVSHPKAKPLAESSIPSEALTAVSEALPAATADDDDSQQ
                     LLLSGMSCASCVTRVQNALQSVPGVTQARVNLAERTALVMGSASPQDLVQAVEKAGYG
                     AEAIEDDAKRRERQQETAVATMKRFRWQAIVALAVGIPVMVWGMIGDNMMVTADNRSL
                     WLVIGLITLAVMVFAGGHFYRSAWKSLLNGAATMDTLVALGTGVAWLYSMSVNLWPQW
                     FPMEARHLYYEASAMIIGLINLGHMLEARARQCSSKALEKLLDLTPPTARLVTNEGEK
                     NVPLADVQPGMLLRLTTGDRVPVDGEITQGEAWLDEAMLTGEPIPQQKGEGDSVHAGT
                     VVQDGSVLFRASAVGSHTTLSRIIRMVRQAQSSKPEIGQLADKISAVFVPVVVVIALV
                     SAAIWYFFGPAPQIVYTLVIATTVLIIACPCALGLATPMSIISGVGRAAEFGVLVRDA
                     DALQRASTLDTVVFDKTGTLTEGKPQVVAVKTFADVDEAQALRLAAALEQGSSHPLAR
                     AILDKAGDMQLPQVNGFRTLRGLGVSGEAEGHALLLGNQALLNDQQVDTKAIEADISA
                     QASQGATPVLLAVDGKAVALLAVRDPLRSDSVAALQRLHKAGYRLVMLTGDNPTTANA
                     IAKEAGIDEVIAGVLPDGKAEAIKRLQSEGRQVAMVGDGINDAPALAQADVGIAMGGG
                     SDVAIETAAITLMRHSLMGVADALAISRATLRNMKQNLLGAFIYNSIGIPVAAGILWP
                     FTGTLLNPVVAGAAMALSSITVVSNANRLLRFKPKE"
     gene            111432..112364
                     /gene="glsA"
                     /locus_tag="IRB70_000326"
     CDS             111432..112364
                     /gene="glsA"
                     /locus_tag="IRB70_000326"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBC0630285.1"
                     /translation="MLDANKLQQAVDQAYTQFHSLNGGQNADYIPFLANVPGQLAAVA
                     IVTCDGNIYRAGDSDYRFALESISKVCTLALALEDVGPQAVQDKIGADPTGLPFNSVI
                     ALELHGGKPLSPLVNAGAIATTSLINAENTEQRWQRILHIQQQLAGEQVALSDEVNQS
                     EQTTNFHNRAIAWLLYSAGYLYCDAMEACDVYTRQCSTLINTVELATLGATLAAGGVN
                     PLTHKRVLQADNVPYILAEMMMEGLYGRSGDWAYRVGLPGKSGVGGGILAVVPGVMGI
                     AAFSPPLDEEGNSVRGQKMVASVANQLGYNVFKG"
     gene            112367..113659
                     /locus_tag="IRB70_000327"
     CDS             112367..113659
                     /locus_tag="IRB70_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBC0630286.1"
                     /translation="MMNTEGNNDNKPLGLWNVVSIGIGAMVGAGIFALLGQAALLMEA
                     STWVAFAFGGIVAMFSGYAYARLGASYPSNGGIIDFFRRGLGNGVFSLALSLLYLLTL
                     AVSIAMVARAFGAYAVQFLHEGSQEEHLILLYALGIIAVMTLFNSLSNHAVGRLEVIL
                     VGIKMMILLLLIIAGVWSLQPAHISVSAPPSSGAFFSCIGITFLAYAGFGMMANAADK
                     VKDPQVIMPRAFLVAIGVTTLLYISLALVLLSDVSALELEKYADTAVAQAASPLLGHV
                     GYVIVVIGALLATASAINANLFAVFNIMDNMGSERELPKLMNKSLWRQSTWGNIIVVV
                     LIMLMTAALNLGSLASVASTTFLICYLAVFVVAIRLRHDIHASLPILIVGTLVMLLVI
                     VGFIYSLWSQGSRALIWIIGAILLSLIVAMVMKRNKTV"
     gene            113784..114191
                     /gene="cueR"
                     /locus_tag="IRB70_000328"
     CDS             113784..114191
                     /gene="cueR"
                     /locus_tag="IRB70_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(I)-responsive transcriptional regulator"
                     /protein_id="HBC0630287.1"
                     /translation="MNISDVAKITGLTSKAIRFYEEKGLVTPPMRSENGYRTYTQQHL
                     NELTLLRQARQVGFNLEESGELVNLFNDPQRHSADVKRRTLEKVAEIERHIEELQSMR
                     NQLLALANACPGDDSADCPIIENLSGCCHHRAG"
     gene            complement(114395..114817)
                     /locus_tag="IRB70_000329"
     CDS             complement(114395..114817)
                     /locus_tag="IRB70_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630288.1"
                     /translation="MMNSSIKSFSLLAVILLTGCSSPTSRIADCQAQGVSHDTCYLAE
                     QQRQTAILSASEAQAFKNAEAAQHAQAAKKAIYKGFGMTFRMSSKNFAYLNDSLCAID
                     EDNKDATVYQSGLYNVIVYHHTGKVALMKEGQFVGYLK"
     gene            complement(114902..115918)
                     /locus_tag="IRB70_000330"
     CDS             complement(114902..115918)
                     /locus_tag="IRB70_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YadA family autotransporter adhesin"
                     /protein_id="HBC0630289.1"
                     /translation="MKTVNVALLALIISATSSPVVLAGDTIEAAATELSAINSGMSQS
                     EIEQKITRFLERTDNSPAAYTYLTEHHYIPSETPDTTQTPTVQTDPDAGQKTVAATGD
                     AQTPARYQSMINARQSAVTDAQQTQITEQQAQIVATQKTLAATGDTQNTAHYQEMINA
                     RLAAQNEANQRTTTEQGQKMNALTTDVAAQQQKERAQYDKQMQSLAQKSVQAHEQIES
                     LRQDSAQTQQQLTNTQKRVADNSQQINTLNNHFDSLKNEVEDNRKEANAGTASAIAIA
                     SQPQVKTGDVMMVSAGAGTFNGESAVSVGTSFNAGTHTVLKAGISADTQSDFGAGVGV
                     GYSF"
BASE COUNT        28390 a        29120 c        30698 g        27850 t
ORIGIN      
        1 agagaaacgt ttcgctggta atcaaacaaa aaatatttgc gcaaagtatt tcctttgtca
       61 taaaaataat acttccagac actatgaagt tgtgaaacat aatgttaact tctccatact
      121 ttggataagg aaatacagac atgaaaaatc tcattgctga gttgttattt aagcttgccc
      181 aaaaagaaga agagtcgaaa gaactgtgtg cgcaggtaga agctttggag attatcgtca
      241 cggcaatgct tcgcaatatg gcgcaaaatg atcaacagcg gttgattgat caggtagagg
      301 gggcgctgta cgaggtaaag cccgatgcca gcattcctga cgacgatacg gagctgctgc
      361 gcgattacgt aaagaagtta ttgaggcatc ctcgtcagta aaaagttaat cttttcaaca
      421 gctgtcataa agttgtcacg gccaagactt atagtcgctt tgtttttatt ttttaatgta
      481 tttgtacatg gagaaaataa agtgaaacaa agcactattg cactggcact cttaccgtta
      541 ctgtttaccc ctgtgacaaa agcccggaca ccagaaatgc ctgttctgga aaaccgggct
      601 gctcagggcg atattactgc acccggcggt gctcgccgct taacgggtga tcagaccgcc
      661 gctctgcgtg attctcttag cgataaacct gcaaaaaata ttattttgct gattggcgat
      721 gggatggggg actcggaaat tactgccgca cgcaattatg ccgaaggtgc gggcggcttt
      781 tttaaaggta tcgatgcctt accgcttacc ggacaataca cacactatgc gctgaataaa
      841 aaaaccggca aaccggacta cgtcaccgac tcggctgcat cagcaaccgc ctggtcaact
      901 ggtgtcaaaa cctataacgg cgcgctgggc gtcgatattc acgaaaaaga tcacccaacg
      961 attctggaaa tggcaaaagc cgcaggtctg gcgaccggta acgtttctac cgcagagttg
     1021 caggatgcca cgcccgctgc gctggtggcg catgtgacct cgcgcaaatg ctacggtccg
     1081 agcgcgacca gtgaaaaatg tccgggtaac gctctggaaa aaggcggaaa aggatcgatt
     1141 accgaacagc tgcttaacgc ccgtgccgat gttacgcttg gcggcggcgc aaaaaccttt
     1201 gctgaaacgg caaccgtcgg cgaatggcag ggaaaaacgc tgcgtgaaca ggcacaggcg
     1261 cgtggttatc agttggtgag tgatgctgcc tcgctaaatg cggtgacgga agcgaaccag
     1321 caaaaacccc tgctaggact atttgctgac ggcaatatgc cagtgcgctg gctaggaccg
     1381 aaagcaacgt accacggcaa tatcgacaag cccgcagtta cctgtacgcc taatccgcaa
     1441 cgtaatgaca gcgtaccgac cctggcgcag atgaccgaca aagccattga attgttgagt
     1501 aaaaatgaga aaggcttttt cctgcaagtt gaaggtgcat caatcgataa acaggatcac
     1561 gctgcgaatc cttgtgggca aattggcgag acggtcgatc tcgatgaagc cgtacaacgt
     1621 gcgctggaat tcgctaaaaa ggatggcaac acgctggtca tagtcaccgc tgatcacgcc
     1681 cacgccagcc agattgtcgc gccggacacc aaagcgccgg gcctcaccca ggcgctaaat
     1741 accaaagatg gcgcagtgat ggtgatgagt tacgggaact ccgaagagga ttcacaagaa
     1801 cataccggca gtcagttgcg tattgcagcg tatggcccac atgccgccaa tgtcgttgga
     1861 ctgaccgacc agaccgatct cttctacacc atgaaagccg ccctggggct gaaataaaac
     1921 cgcgcccggc ggtgaatttt tgctgtcggg tggttttttt gctgttagca accagactta
     1981 atggcagatc acgggcgcaa acgctcatgg ttaaaacatg aagagggatg gtgctatgaa
     2041 aataacatta ctggttacct tgcttttcgg actggttttt ttaaccaccg tcggcgctgc
     2101 cgagagaacc ttaaccccgc aacaacagcg tatgacctcc tgtaatcagc aggcgacggc
     2161 gcaggcgttg aaaggggatg ctcgtaagac ctacatgagt gattgcctga agaacagcaa
     2221 gtctgcgcct ggtgaaaaaa gtttgacgcc acagcagcaa aagatgcgcg aatgtaataa
     2281 tcaagcaacg caacaatctc tgaaaggtga tgatcgtaat aagtttatga gcgcctgcct
     2341 caagaaagcc gcctgatacc tgatagtgct aacgggtgag ctacgaaaat ggctcacccg
     2401 aaatttcata cttctgcctt tagccccgtc tctataattt gggaaaattg tttctgaatg
     2461 ttcccaaaaa taatgaatga tgaaaacttt ttcaaaaaag cggcggcgca tggggaggaa
     2521 cctcctttaa ctcctcaaaa cgaacatcag cgatccgggc tgcgcttcgc ccgtcgcgtc
     2581 agactacccc gcgcggttgg cctggctggc atgttcttac cgattgcttc aacgctggtt
     2641 tcgcacccgc cgccgggctg gtggtggctg gtgttggtcg gctgggcgtt cgtctggccg
     2701 catttagcct ggcagatagc gagcagggcc gtcgatccgc ttagccggga aatttacaac
     2761 ttaaaaaccg atgcagtatt agcgggaatg tgggtaggcg taatgggcgt aaacgtgctg
     2821 ccttccaccg cgatgttgat gattatgtgt ctgaatttga tgggggcagg cggcccccgt
     2881 ctgtttgtcg cgggtctggt gttgatggtg gtttcctgcc ttgtcaccct cgaactgacg
     2941 ggcatcaccg tgtcgttcaa tagtgcgccg ctggaatggt ggctctccct tcccattatc
     3001 gtcatttatc ctctgctgtt tggctgggtc agctaccaga cggcgactaa actggcggaa
     3061 cataaacgca ggttgcaggt catgagtacc cgcgacggta tgacgggcgt gtataaccga
     3121 cgtcattggg aaactatgtt acgcaatgaa tttgataact gtcggcggca taaccgcgat
     3181 gcgacattac tgattatcga tatcgaccat ttcaagagca tcaacgatac ctggggccat
     3241 gatgtgggcg atgaagcgat tgtggcgctt acccgacagt tacaaataac cctgcgcggt
     3301 agcgatgtga ttggtcggtt tggcggcgat gagtttgcgg taatcatgtc cggtacgcca
     3361 gctgagagcg ccattaccgc catgttacga gtgcatgaag ggctaaatac attacgtctg
     3421 ccgaatacgc cacaggtaac tttacggatt agtgtggggg ttgcgccgct gaacccacaa
     3481 atgagtcact atcgtgagtg gttgaaatcg gcagatttgg cgctttacaa agcaaagaaa
     3541 gccggacgta accgcaccga agtggcggcc tgacgtccgg caaaagtcat caggatttac
     3601 tgagtttttc tgatttttcc atacacttcg tcatcgcttc gatcactgcg gcacggaagc
     3661 ctttctcttc cagtacgcgt accgcctcaa tggtggtgcc tcccggtgag cagaccatat
     3721 ctttcagtgc ccctggatgt tctcccgttt ccagcaccat ttttgcggaa cccattaccg
     3781 cctgagcggc aaatttatac gcctgggcgc gtggcatccc gcccagcacg gcggcgtcgg
     3841 ccatcgcttc gataaacata aagacgtagg ctggcgaaga accgctcaca ccgaccaccg
     3901 ggtggatcat cggctcggca attacttccg cttcgccaaa gcagcggaaa atattcagca
     3961 catcagcggt atcttctggg gttaccagcg cgtttggcgt tacggaggtc atcccggcat
     4021 taaccagcgc gggagtgttc ggcatggcgc ggataatttt ccggtcatgg cccagcgcgc
     4081 gggcaagctg gtcgagtgtg atacctgcag caatagaaac gaccagagag tctttattca
     4141 ggctggaggt gatttcgcta agcactttaa tcatgatgcc aggtttaacg gcggcaaaaa
     4201 tgatgtcggc gatttgcgcc acttcttgcg ccgattctgc ggcgttgatg ccgaactggt
     4261 catgcagggc ggcgacttta tccggggagg gggtatatac ccagatttgc cctggaagca
     4321 cctgaccgct ggcaatcaga ccgccgagaa tggcttttcc catattgccg cagccaataa
     4381 aaccgatttt cttttccatt gcctcactcc tgccgtgaaa ttcattgttt tgataatcgc
     4441 tggcagaagc ataaacagaa ctatgccgga aggcaaaagc gcgacacaat agaggattac
     4501 ccaacaaagg atgactttat gacaatttgg gtggatgccg acgcgtgtcc caatgtaatt
     4561 aaagagattt tgtatcgcgc ggcggaacgt atgcagatgc cgctggtact ggtagcaaac
     4621 cagagtttac gcgtgccgcc atcgcgattt attcgtacgc tgcgcgtcgc ggcaggtttc
     4681 gacgttgccg ataacgaaat tgtccggcag tgtgaagcgg gcgatttggt gatcaccgca
     4741 gatatacctt tggctgctga agccatcgag aaaggcgcgg cggcgcttaa tccacgcggc
     4801 gaacgttaca cgccagcgac cattcgtgag cgcctgacga tgcgcgattt tatggatacc
     4861 ttacgtgcca gtgggatcca gaccggagga ccagatagtc tttcacaacg tgaccgccag
     4921 gcctttgctg cggagctgga gaagtggtgg ctggaagtgc aacgtagtcg tggctaaatg
     4981 taatttatta tttacacttc attcttgaat atttattggt atagtaaggg atgtattgag
     5041 attttcacct taagtggaat tttttcttta caatcgaaat tgtactagtt tgatggtatg
     5101 atcgctattc tcatgacacc ggctttcgcc gcattgcgac ctattgggga aaacccacga
     5161 tgacacaacc tctttttctg atcgggcctc ggggctgtgg taaaacaacg gtcggaatgg
     5221 cccttgccga ttcgcttaac cgtcggtttg ttgataccga tcagtggttg caatcacagc
     5281 tcaatatgac ggttgcggag atcgtcgaaa gggaagagtg gacgggattt cgcgccagag
     5341 aaacggcggc gctggaagcg gtaactgcgc catccaccgt tatcgccacg ggcggcggca
     5401 ttattctgac ggaatttaat cgtcacttta tgcaaaataa cgggatcgtg gtttatttgt
     5461 gtgcgccagt atcagtcctg gttaaccgac tgcaagctgc accggaagaa gatttacggc
     5521 caaccttaac ggggaaacca ctgagcgaag aagttcagga agtgctggaa gaacgcgatg
     5581 cgctttatcg cgaagttgcg catattatca tcgacgcaac aaacgaaccc agccaggtga
     5641 tttctgaaat tcgcagtgcc ctggcacaga cgatcaattg ttgattttcg agcgcctata
     5701 cttaacgttc atcccgtgaa ataaggaaga acgatgccaa cgaaaccgcc ttatcctcgt
     5761 gaagcatata tagtgacgat tgaaaaagga aaaccaggac agacggtaac ctggtaccaa
     5821 ctcagagccg atcatcctaa accagactcg ttgatcagtg aacatccgac cgctcaggaa
     5881 gcgatggatg cgaaaaaacg ctatgaggac cctgacaaag agtgaccgca tcagactgct
     5941 cggaagggat tctgagtgcc accacaaggg atctgcgtca catttttcac aattcatgtt
     6001 tttcaaataa ttagaatatt aaagaataac aatccattac tggaatcatt tggaatcttt
     6061 acattatgcc gtgcaggtct gctgctacgc tttttgtcat ttgtagcaca ggtaagtgtc
     6121 agcagtggtg cttagcgctt gcccggtaat taacgacgaa ataaaagtaa ggtggaagaa
     6181 caatgagtgc gtcgttggcg atcctgacca tcggcattgt acctatgcag gaagttttgc
     6241 cgctcctgac agaatacatt gacgaagata atatttccca tcatagcctg ctggggaagt
     6301 taagccgcga agaagtgatg gcggagtacg cgccagaagc aggcgaagac accattctca
     6361 cattattaaa tgacaaccag ctggcccatg tttcgcgtcg taaagtggaa cgagacctgc
     6421 aaggtgtggt tgaagtgctc gataatcagg gttacgacgt cattatatta atgagtacag
     6481 caaacattag tagtatgacc gcgcgtaata cgatctttct tgagccgtcg cggatattgc
     6541 caccgctggt ttcctctatt gttgaagatc atcaggtggg ggttatcgtt ccggttgagg
     6601 agttgctgac cgttcaggca caaaaatggc aaattttgca gaaaccgcca gtattttcat
     6661 tgggtaaccc cattcatgat tcggaacaaa aaatcattga tgccgggaaa gaattactgg
     6721 caaaaggggc tgatgtcatc atgctggatt gtttaggatt tcaccaacgt catcgcgatt
     6781 tactgcaaaa acagctcgat gttcctgtct tgctctctaa cgtattgatt gcacggctgg
     6841 ctgcggaatt actggtgtaa ttttgcgtga cagccagcgc ctctggcccc tatagtgaag
     6901 tagatgttca actaccagac agggccagtt tatgcttcaa agtaatgagt acttttccgg
     6961 caaagtgaaa tcgatcggct tttccagcag cagcactggt cgcgccagcg tgggtgttat
     7021 ggttgaaggt gaatacacct tcagcaccgc tgagcctgaa gagatgacga taatcagtgg
     7081 cgcgctgaat gtgttactgc ctgacgcgac cgactggcaa gtgtatgaag ccggttcggt
     7141 gtttaatgtt cccggtcaca gcgagtttca tctgcaagtt gccgaaccca cctcttatct
     7201 gtgccgctat ctgtaattcc tcgccttccc cttgaacggg agggcatttt tctgaaatgt
     7261 cctctcttta acccataata atatttcctt tgctgggatt ttttcgattt ccgatatatt
     7321 cataattcat caaggttgat ataaatatca gcgaagatct ccagatattg ttgcggaact
     7381 ggcgacgata aaagataaat cagatgatga atggtggcgt gcattgctgc aaagtcgcaa
     7441 tgatcatttg cgccaaacgg cattgcgcaa cgcacatacc ccggtgttgt taacgacatt
     7501 gactgagtct caggatcggt cgctggctat taataatcca cagctggctg ccgatgtgaa
     7561 aacggtgtgg ctaaaagagg agccatcatt actcttattt gtcgatcaac ccgctctttc
     7621 gcagttacgg gatttagtga aaatcggggc aacgcggaaa attcgcagtg aagcgcgtca
     7681 ccggcttgag gaaaaacaat gacacaacgc ccctggagca agttacagcg taaaacgcat
     7741 aatattgctg cgcaaaatat tattgcccgc cgtagcgaat aattatatgc ctggtgtggc
     7801 ttcgtacgcc ggataagacg cggcaggcgt cgcatccggc attaaaggta aatcagcaat
     7861 taacgttgtg cttcgccacc taatccttca atcaggtttt gaattaacgc tgccagttca
     7921 ccagtcatca ggatgaaatc ggcatcaaaa cgctgggcga aatcttcacg gtcgatatct
     7981 tcgttttgat cgcgcagctc gtcgcagaac ttcagacgct tgagcgaacc atcgtcgcac
     8041 atcacaaact gaatgcgttg ctgccagtcg agcgccagtt tagtcaccac ttttccggct
     8101 tcgatgtggt tggtgatctc ttcgctggtc agatcttgtt tcttcgcgcg gatcacgcca
     8161 ccatcttcca gcagcgattt cagctcggct tcatcaagca actggaagcc ctgtgccgca
     8221 ctaccggagc gaacccattc ggtcagcgtc agttcaatcg ggttttccat gctcaatggt
     8281 acaaccggta acgaccccag gcttttacgc agtaatgcca gcgtatcttc cgcttttttg
     8341 gcactggcgc agtccaccat aatcaaaccg ttaaccgtgt cgatccacat cattgtctgg
     8401 ctaaaacggc tgaaagcacg cggcagcaga gagtgcagca cttcgtcttt cagcgaatct
     8461 ttttcggttt tcttcagctt acgcgcctgt tccgcttcca gtttggcgat tttcgcttcc
     8521 agcgcctgtt taatcaccgg agacgggagg attttttctt ctttgcgcgc gcagataaca
     8581 atttgaccat tggcaacgtg cgttaacgca tcgctgtgcg atcccatcgg aggaacccag
     8641 cccatcttcg ccatgtcctg gctgccgcat ggggtaaatg ccatcgaggc tagctgtttt
     8701 tccatctctt ctgcacgcag cgaaatctcg cggctaagac ggtaaaccat taaatttttg
     8761 aaccacagca tgataatttc cacggccttg tcgttaaatt tagcgggcat gataacgaat
     8821 tgtcggcggg cttgcattgc caatccggtt gtccgtctct acgctattga tattgaaaaa
     8881 aataaggaga gtaccgtgcg tataggtatc gatttaggcg gcaccaaaac tgaagtgatt
     8941 gcactgggcg atgcagggga gcagttgtac cgccatcgtc tgcccacgcc gcgtgatgat
     9001 taccggcaga ctattgaaac gatcgccacg ttggttgata tggcggagca ggcgacaggg
     9061 cagcgcggaa cggtaggtat gggcattcct ggctcaattt cgccttacac cggcgtggtg
     9121 aagaatgcca attcaacctg gctcaacggt cagccattcg ataaagactt aagcgcgagg
     9181 ttgcagcggg aagtgcggct ggcaaatgac gccaactgtc tggcggtttc agaagcagta
     9241 gatggcgcgg cagcgggagc gcagacggta tttgccgtga ttatcggcac gggatgcggc
     9301 gcgggcgtgg cattcaatgg gcgggcgcat atcggcggca atggcacggc aggcgagtgg
     9361 gggcacaatc cgctaccgtg gatggacgaa gacgaactgc gttatcgcga ggaagtccct
     9421 tgttattgcg gtaaacaagg ttgtattgaa acctttattt cgggcacggg attcgcgacg
     9481 gattatcgtc gtttgagcgg acatgcgctg aaaggcagtg aaattatccg cctggttgaa
     9541 gaaagcgatc cggtagcgga actggcattg cgtcgctacg agctgcggct ggcaaaatcg
     9601 ctggcacatg tcgtgaatat tctcgatccg gatgtgattg tcctgggggg cgggatgagc
     9661 aatgtcgacc gtttatatca aacggttccg cagttgatta aacaatttgt cttcggcggc
     9721 gaatgtgaaa cgccggtgcg taaggcgaag cacggtgatt ccagcggcgt acgcggcgct
     9781 gcgtggttat ggccacaaga gtaaaaaacc caggcaattg gcgcatcatg cctgatgcga
     9841 cgcttgccgc gtcttatcag gcctgcaaaa tgtgccggaa ccgcaggccg ataacgcgtt
     9901 catgccgcat ccggcaataa gcaacgcgca acgtgactgc aatctacccc agtggtttcg
     9961 ccagcaccgg actatccgcc gcttgctggc gcttatagcg accatacagc agcaacgacg
    10021 acatcgcagc aaacgaaagc agggcggcag gcagcgccac gtaattatat gccatcccca
    10081 gcgtcagcat cataccaccg caatatgcgc cgacggcgct accgaggtta aacgctattt
    10141 gcccacctgc ggcacctaat aactctccgc cttttgcgtt ttgcagtaac aatatttgca
    10201 gaggtgctga aagggcaaat aatcccgcgc aacaaataaa agcaaaaata agcgacgtta
    10261 ttttcatgcc gccgaagaaa aagagcatca acagtgccag tacaatgata aagtcagtca
    10321 ctgctgcaat gcgcagtggt gaataacgtc ctgaaatccg gccacttagc acattcccca
    10381 gcaccatccc tagccccact aacatcataa taaaggtcat cgccgtttcc gaaaaaccgg
    10441 aaataaacat catgtatggc tttacgtagc tgaaccaggc aaacacacct gcgttgccaa
    10501 acatcgtagc ggcgaaaatt aaccacgggg cagggctgcg taaaaagtga aattgttcgc
    10561 gtagttttcc tttcgcctcg tcgcgaatat ccggcaccca aaaatagacc gatgccatca
    10621 ccgcaatatt aaaaacagcg atcaacaaaa aggtgtagcg ccagctaaat tcctgactta
    10681 aatacgttcc cagtggaatg cccagcaaat tggcgactgt catcccggaa accatccctg
    10741 ccacggcggc ggtgactttg ccgggtttga taatttttga taacacgatc gctccgacgc
    10801 caaaaaatgc gccatgcgga aagccggata ccagccgacc aatggcgagc atcaggtaag
    10861 acgaagagag cgtgaacatg gcgttgccaa tgacgcacaa cgccaccaga aacaataaga
    10921 tatgtttgag tgagtagcga ctggaaaaaa gcgcgatgat tggcgcaccg accaccaccc
    10981 ccagcgcata atacgagatc atatgcccgg cggcaggaat cgaaattcct acgttatgcg
    11041 ccagctccgt gagcacgccc ataatgccaa attcggccat ccccaaacca aacgtgccca
    11101 gagccaaaga taaaatgact tttttcatac caccatcaca accaccagaa cggctactaa
    11161 tcaccgtagc caataaagtg atagcttgca ggataacgac cagcgaggcc aagagataat
    11221 tcgcccctct gtattcatta tcctgctgaa tagttatttc actgcaaacg cactttccag
    11281 tttgctgtag cccagtccat tgatcttttt cactttgatc tgcaccggaa tacgctcttt
    11341 catcgcttca acgtggctaa tcacaccgat ggttttgcca ctggcattca gggcatccag
    11401 cgcatcaagg gcggtatcca gcgtttcgct atccagcgtg ccaaaacctt catcaaggaa
    11461 cagcgagtca atacgcgttt tatggctgac cagatccgaa agcgccagcg ccagcgccag
    11521 actgacgagg aaactttcgc cgccggaaag ggtacgggta tcgcgtaccg catctgcctg
    11581 ccaggtatca acaacctcga cttccagcgc ctcgctggct ttgcgctgta acagatagcg
    11641 cccgtgcagc cgggtaagtt gctgattagc gagatggact aaattatcca gcgtcagccc
    11701 ctgggcaaac ttgcggaatt tatcgccctc tttggaacct attagcgaat tcagatatcc
    11761 ccagtcctca acctgctgcg tcatttgagc aatttgctgc attaaggttt gttgttgctg
    11821 acggttgtct gcatcctgct tcagctgctg gcgaatctcg ccctgactgg tggtattttc
    11881 acgcaacttt tgctgagttt gcgctaactc ttgctgaatc tgctccaccg tcacactgag
    11941 atccaggccg tcaggtcggt gttgctgatg ctgtgccagc gcttctgctg tctgagtgac
    12001 cagcgtttgc gcctgacggc gctggttttc cagattctgc ttgagctgtt ccagttgcgt
    12061 tagtgtttgt tcatccatta gcgccgcaag gaacgcctgt tgatcgtcaa agacactggc
    12121 ctgtagcgcg gtgtcaaact gcgcctgggc tttttgcaga ctttgcgccg ccagaacatc
    12181 ctgttgctgt aacgtctgct gctggctgtg taatgcgaga cattgttcat gaacctgccg
    12241 ccagttttcc agcgccacag tttcttcgct gtgcgggagt tcatcacttt gcggcaacgt
    12301 ttccagaatc ggcgtcagct gctgcatacg gttttgcagc gcggttaatt cgttctggcg
    12361 ttgctgccag ctctgggctt cttgctgacg cgtcgccaac cagctctctt cttcatcttc
    12421 ctgtggcaat gtcagtgcat aacccgccaa tgccgttaag agttgctgct ggcgttgttc
    12481 aatttgctgt tgatactgga taatttgttg attatgcgca gcaatctgcc cttgtacttc
    12541 atgtcgttgg ctgagtaatc gcagctggcg ctcgtgctca tcttgtgcat ccagccacgg
    12601 ttgaatatcg tcctgtggct gcaaggtgat attgaggctg gccgtgacgg cttgccattg
    12661 ttgagtaagt gcttgctcat cttgtcggag gctttgcgct tcgttttcat cacgctgaag
    12721 ttgctttgtt aaggcgtcca gttgcccacg tagcgtcgca ccttcttcac cgagcttttt
    12781 aacttcgttt tccagcgcca gtaatcgaga ctgattaacg ccaggctcca gcgcctgata
    12841 cgcctcgacc gccgggtggc tggtggaacc acaaagtgga caaggctgac ccgcctgtaa
    12901 ctgcgcgcgc tgggcttcca gcgttttgat gcgtgcttcc tgctcgcaaa tggttttgac
    12961 atcggcaagt tgctgcatct tttctttata acgctggcgc atttcgttaa gtgcggcgtt
    13021 acgttgcgtc tgttcttgcg tgacattctg gatagtgacc tgtaattgcg ccaggcgttt
    13081 ttgttgggga acaatctgtc catgcagcgc gaccaggcgc tgacgcagtg ggcgttgctc
    13141 ggcatgttgc gccagggcgc tagcaacttc atcggcggtt aacgtcaacg tgatcgccgc
    13201 aagcgcatta agtttttgct ctgcatgggt taactgttgc tgccattgcc gcagatgctc
    13261 gcgatcgctg gtttgttggg agaactgcgc acgccaaccc gccagttcgt tgttccactg
    13321 acggaagcgg tcgtgttcct gtagccaggc attcagactt tgttgctgct gctgtaattc
    13381 tgctgactgc ttcgccgcgt ggtggcgaat gctcgcccga agcgccattg tgctctgtaa
    13441 gcgagtattt acttcttcaa tctgctggcg agtatgcgcc agcgccgcgc tgtgttctgc
    13501 gatgcgttcc cagtgcggac gaagatttcg tgccggttgt gccagactga gcgccgccag
    13561 ttgaggttgc gctttttctt cttcggctaa cgcctgttgc aaggcctgtt gacggcggct
    13621 ggcttcttgc tgcaattcgt ccagacgcgt taaccagttt agtgattgtt gttcttgctg
    13681 ctgcgcggta agtaactgtt tttcttcgtc agtaagtacc tgcaaactcg ctgtcagcga
    13741 ttgcacttgt tctggcgtga gcaacgcgac gccgctggcc tgcgcttgca gcttttccag
    13801 ctctgtgcgg gccgatttgt gctgctcaaa aaccatcgcc gagatttgcc cgtagatttc
    13861 agtgccagtt aactcctcga gcaattccgc gcgttctttt ggtttggcat tcaggaaggc
    13921 agcaaattgc ccctgcgaaa gcagcatcga acgggtgaag cgcccgtaat ccagtccggt
    13981 taacgtcgcc gtcagttcca gcttatcttt cactttgtcg gcgagaattt tgccatcggc
    14041 gcagcgcgcc agctctacgc gtggcacctg caaattaccg tccggctggt tacgcgcccg
    14101 attctggctc cagaacgcgc gatacacttc acctttcact tcaaactcca cttccgccag
    14161 acattcggcg gtatcgcggg tcatgagatc attttgcgat tgtgaaacgt tagagaggcg
    14221 cggagtttcg tgatacagcg ccagacaaat ggcgtccagc agggtggttt tccccgcacc
    14281 ggttgggccg gtaatcgcaa acagcccgtt gctggcgaac ggctcgcggg tgaaatcaat
    14341 cttccattct ccttttaatg agttcaggtt tttcaggcgc aggctgagaa ttttcatact
    14401 tcgtgttctc cggcgagggt atgcaacgtc gtggtgaaaa gatactgcag acgttgctgc
    14461 tgcgattcat ccagttcttc cagtgccaga cggcgattga acacctcttc gacgctgagt
    14521 tcgctgaggg tttcacgctg ttggctggct aacacacgct cgcgctgttc acgactccgg
    14581 cgtaccagca atacttcaac gggcaatgat tcggttaatg cctggatttt gcgctgaata
    14641 tcatgcagat actcatcagt agtgatttcg atatccagcc agacaggtgg ctcctgtgat
    14701 acatcgcgcc actgttccag ctgtgcggta atcgacgcca gatcgccttt cagcaccgcc
    14761 atgggttgcg ttaccggtac gttcaggttt tccacgttct ctaatttgcc gtttgaaaat
    14821 gtcaccagat ggacatattt actcttaccg cattcatcaa aactcagtgg tatgggggaa
    14881 ccgcaatagc gaacatgttc catgccgcca ataatctgcg cgcggtgaat atgcccgagc
    14941 gcgatgtagt cggctggtgg aaagttttgt gccggaaacg cgtccagcgt gccaatataa
    15001 atgtcacgca cggcgtcact tttactggca cccacggtcg ttaaatgtcc cgtggcgatg
    15061 atgggcagag gctgatcgcc gcgcagtttg caggcatcgg cataatgttg ttgataataa
    15121 tcagtaatag ccgccagcaa atgctgctgt ttttcaatac cgttaagccc cgcctggctg
    15181 gtaataatgt cacgcgggcg taaaaaaggt atgggacaca gcactgcgcc tggcgtcccg
    15241 tcgcgacgag gcaagatttg cggcgcatgt ccggcgctgg cgaccacggt agtattgagg
    15301 aacgccatga tatcgcgcga ttcattcagc gtggcgaccg agtcatggtt tcctgccagt
    15361 accaccagat gacagccagt ttgctgtaaa ttgacaacaa aacggttgta taacgtgcgg
    15421 gcgtaactgg gcggcgagcc ggtatcgaaa acatcaccgg caacaataat cgcatccacc
    15481 tgatggatct gtgctgtctc cagcagccag tcaagaaaag cctgatgttc ggcttcgcgg
    15541 ctcttactgt agaagttctg gccgagatgc cagtctgagg tgtgaaggat gcgcataacg
    15601 gttccctggc gaaaaagcat gggcgcgatt atacccaaac agatgtgcca tttgcttttt
    15661 tctgcgccac ggaaatcaat aacctgaaga tatgtgcgac gagcttttca taaatctgtc
    15721 ataaatctga cgcataatga cgtcgcatta atgatcgcaa cctatttatt acaacagggc
    15781 aaatcatggc gagacgtatt ctggtcgtag aagatgaagc accaattcgc gaaatggtct
    15841 gcttcgtgct cgaacaaaat ggctttcagc cggtcgaagc ggaagattat gacagtgctg
    15901 tgaatcaact gaatgaaccc tggccggatt taattctcct tgactggatg ttacctggcg
    15961 gctccggtat ccagttcatc aaacacctca agcgcgagtc gatgacccgg gatattccag
    16021 tggtgatgtt gaccgccaga ggggaagaag aagatcgcgt gcgcggcctt gaaaccggtg
    16081 cggatgacta tatcaccaag ccgttttcgc cgaaggagct ggtggcgcga atcaaagcgg
    16141 taatgcgccg tatttcgcca atggcggtgg aagaggtgat cgagatgcag gggctaagtc
    16201 tcgacccgac atctcaccgg gtgatggcgg gcgaagaacc gctggagatg gggccgacag
    16261 aatttaaact gctgcacttt tttatgacgc atcctgagcg cgtgtacagc cgcgagcagc
    16321 tgttaaacca cgtctgggga accaacgtgt atgtggaaga tcgtacagtc gatgtccaca
    16381 ttcgtcgcct gcgtaaagca ctggagcccg gcgggcatga ccgcatggtg cagaccgtgc
    16441 gcggtacagg gtatcgtttt tcaacccgct tttaacgcct tgctcatcgg acgcagagca
    16501 gggcttatga attcttaact ggagtatctt acgtgctgga acggctgtcg tggaaaaggc
    16561 tggtgctgga gctgctactt tgctgcctcc cggctttcat cctgggtgca ttttttggtt
    16621 acctgccctg gtttttgctg gcatcggtaa cgggactgct tatctggcat ttctggaatt
    16681 tattgcgcct ttcatggtgg ctgtgggtgg atcgtagtat gaccccgcca ccggggcgtg
    16741 gtagctggga accgctgcta tacggcttac accagatgca gctgcgaaat aaaaaacgcc
    16801 gccgcgaatt gggcaatctg attaaacgct ttcgtagtgg cgcggagtcg ctgcccgacg
    16861 cggtagtgct gaccacggaa gagggcggta ttttctggtg taacggtctg gcgcaacaga
    16921 ttcttggttt gcgctggccg gaagataacg ggcagaacat ccttaacctg ctgcgttacc
    16981 cggagtttac gcaatatctg aaaacgcgtg atttttctcg cccgcttaat ctggtgctca
    17041 acaccgggcg gcatctggaa attcgcgtca tgccttatac ccacaaacag ttgctgatgg
    17101 tggcgcgtga tgtcacgcaa atgcatcaac tggaaggggc gcggcgtaac ttttttgcca
    17161 acgtgagcca tgagttacgt acgccattga ccgtgttaca gggttacctg gagatgatgg
    17221 atgagcaacc gctggaaggc gcggtacgtg aaaaagcgtt gcacaccatg cgcgagcaga
    17281 cccagcggat ggaagggctg gtgaagcaat tgctgacgct gtcgaaaata gaagccgcac
    17341 cgacgcattt gctcaatgaa aaggttgatg tgccgatgat gctgcgcgtt gttgagcgcg
    17401 aggctcagac tctgagtcag aaaaaacaga catttacctt tgagatagat aacggcctca
    17461 aggtgtctgg caacgaagat cagctacgca gtgcgatttc gaacctggtc tataacgccg
    17521 tgaatcatac gccggaaggc acgcatatca ccgtacgctg gcagcgagtg ccgcacggtg
    17581 ccgaatttag tgttgaagat aacggaccgg gcattgcacc ggagcatatt ccgcgcctga
    17641 ccgagcgttt ttatcgcgtt gataaagcgc gttcccggca aaccggtggt agcggattag
    17701 ggttagcgat cgtgaaacat gcggtgaatc atcacgaaag tcgcctgaat attgagagta
    17761 cagtaggaaa aggtacacgt ttcagttttg ttatcccgga acgtttaatt gccaaaaaca
    17821 gcgattaatt cgcctttgtc atcttttatt gccataagcc agccgatgct ggcttatttt
    17881 ctttgcagtc gaaatacggg cgttagattt tacaatggtt ggtgattttt tgttcgcatg
    17941 attagccatg tctttttcat tgaaatagtg ttttatactg gttggtgatt tcttatcgct
    18001 atatacctct ggtttttaga tcccttcttg ctttaaaacg ttataagcgt ttaaattgcg
    18061 cttcaggtgc tgtcatactg actgcattta cgcggtaaat cgaaaaacta ttcttcgccg
    18121 cgcctggttg ggagtatttc ccgctaaaat tgtttaaata taccgctgta tcatccccag
    18181 ggattggcac aaaaatttaa cgttacaaca ccacatccac aggcagtatg atttatgacc
    18241 catcaattaa gatcgcgcga tatcatcgct ctgggcttta tgacatttgc gttgttcgtc
    18301 ggcgcaggta acattatttt ccctccaatg gtcggcttgc aggcaggcga acacgtctgg
    18361 actgcggcat tcggcttcct cattactgcc gttggcctac cggtattaac ggtagtggcg
    18421 ctggcaaaag ttggcggcgg tgttgacagt ctcagcacgc caattggtaa agtcgctggc
    18481 gtactgctgg caacagtttg ttacctggcg gtggggccgc ttttcgctac gccgcgtaca
    18541 gctaccgttt cttttgaagt gggcattgcg ccgctgacgg gtgattccgc gctgccgctg
    18601 tttatctaca gcctggttta tttcgctatc gttattctgg tttcgctcta tccgggcaag
    18661 ctgctggata ccgtgggcaa cttccttgcg ccgctgaaaa ttatcgcgct ggtcatcctg
    18721 tctgttgccg caattatctg gccggcgggt tctatcagca cggcgactga ggcttatcaa
    18781 aacgctgcgt tttctaacgg cttcgtcaac ggctatctga ccatggatac gctgggcgca
    18841 atggtgtttg gtatcgttat tgttaacgcg gcgcgttctc gtggcgttac cgaagcgcgt
    18901 ctgctgaccc gttataccgt ctgggctggc ctgatggcgg gtgttggtct gactctgctg
    18961 tatctggcgc tgttccgtct gggttcagac agcgcgtcgc tggtcgatca gtctgcaaac
    19021 ggtgcggcga tcctgcatgc ttacgttcag catacctttg gcggcggcgg tagcttcctg
    19081 ctggcggcgt taatcttcat cgcctgcctg gtcacggcgg ttggcctgac ctgtgcttgt
    19141 gcagaattct tcgcccagta cgtaccgctc tcttatcgta cgctggtgtt tatcctcggc
    19201 ggcttctcga tggtggtgtc taacctcggt ttgagccagc tgattcagat ctctgtaccg
    19261 gtgctgaccg ccatttatcc gccgtgtatc gcactggttg tattaagttt tacacgctca
    19321 tggtggcata attcgacccg cgtgattgct ccgccgatgt ttatcagcct gctttttggt
    19381 attctcgacg ggatcaaagc atctgcattc agcgatatct taccgtcctg ggcgcagcgt
    19441 ttaccgctgg ccgaacaagg tctggcgtgg ttaatgccaa cagtggtgat ggtggttttg
    19501 gccattatct gggatcgtgc ggcaggtcgt caggtgacct ccagcgctca ctaaatcact
    19561 gaacatttgt tttaaccacg gggctgcgat gccccgtggt tttttattgt gttgatgggt
    19621 taggaattga tggaaagtaa gaacaagcta aagcgtgggc taagtacccg ccacatacgc
    19681 tttatggcac tgggttcagc aattggcacc gggttgtttt acggttcggc agacgccatc
    19741 aaaatggccg gtccgagcgt gttgttggcc tatattatcg gtggtgtcgc ggcgtatatc
    19801 attatgcgcg cgctggggga aatgtcggta cataacccgg ccgccagctc tttctcgcgt
    19861 tatgcgcagg aaaacctcgg cccgctggca ggttacatta ccggctggac ctactgcttt
    19921 gaaatcctaa ttgtcgccat cgccgatgtg accgcttttg gtatctatat gggtgtctgg
    19981 tttccgacgg tgccgcactg gatttgggta ctgagcgtgg tgctgatcat ttgcgccgta
    20041 aacctgatga gcgtgaaggt attcggtgag ctggagttct ggttctcgtt ctttaaagtc
    20101 gccactatca tcatcatgat tgtcgccggt ttcggcatca tcatctgggg aattggcaac
    20161 ggcgggcaac cgaccggtat tcataacctg tggagcaacg gcggcttctt cagtaacggc
    20221 tggcttggta tggtgatgtc gttgcaaatg gtgatgtttg cttacggtgg gatcgaaatt
    20281 atcgggatta ccgccggtga agcgaaagat cctgagaaat ctattccgcg cgcgattaac
    20341 tccgtgccga tgcgtattct ggtgttctac gtcggtacgc tgttcgtcat tatgtctatc
    20401 tacccgtgga atcaggttgg cactgccggt agcccgttcg tactgacgtt ccagcatatg
    20461 gggattacct ttgccgccag cattcttaac tttgttgtgc tgaccgcttc gctgtcggca
    20521 attaacagtg acgtatttgg cgtaggccgt atgctccacg gtatggcaga gcagggcagc
    20581 gcgccaaaaa ttttcagcaa aacctcgcgt cgcggtattc cgtgggttac ggtgctggtg
    20641 atgactaccg cgctgctgtt tgcggtgtat ctgaactaca tcatgccgga aaacgtcttc
    20701 ctggtgatcg cttcgctggc aaccttcgcc acggtgtggg tgtggattat gatcctgctg
    20761 tcgcaaatcg ccttccgtcg ccgtttgccg ccagaagaag ttaaggcgct gaaatttaaa
    20821 gtgccgggtg gggtcgcaac caccatctgc ggtttgattt tcctgctctt tattatcggg
    20881 ttgattggtt atcaccctga tacgcgtatc tcgctgtatg tcggtttcgc gtggattgtt
    20941 gtgctgttga ttggctggat gtttaagcgc cgccacgatc gtcagctggc tgaaaaccag
    21001 taatccttgc gttctgtaag ccggttcagg aggaaatcct gatccggcta ttccgaaagt
    21061 tatccgcccc cgtcctcctc ccccaaatat ccttcagatg atgagtgatc ctgcattagg
    21121 ctatggcaag gtgatcagat tttcatcaca ggggaattat gatgttaaat gcatggcatc
    21181 tgccggtgcc cccatttgtt aaacaaagca aagatcaact gctcattacg ctgtggctga
    21241 cgggcgaaga cccaccgcag cgcattatgc tgcgtacaga acacgacaac gaagaaacgt
    21301 cagtagcgat gcataagcag cgcagtcagc cgcagcctgg cgttaccgca tggcgggcgg
    21361 cgatcgatct ctccagcggg caacctcggc ggcgttatag tttcaaatta ctgtggcacg
    21421 atcgccagcg ttggtttaca ccgcagggct tcagccgaat gccgccagca cgactggagc
    21481 agtttgctgt cgatgtcccg gatatcggcc cacaatgggc tgcggatcag attttttatc
    21541 agatcttccc tgatcgtttc gcccgtagtc ttcctcgtga agctgaacag gatcatgttt
    21601 attaccatca cgcagccgga caagagatca tattgcgtga ctgggatgaa ccggtcacgg
    21661 cgcaggcggg cggatcaacg ttctatggcg gcgatctgga cgggataagc gaaaaactgc
    21721 cgtatctgaa aaaacttggc gtgacggcgc tgtatctcaa tccggtgttt aaagctccca
    21781 gcgtacataa atacgataca gaggattatc gccacgtcga tccgcagttt ggcggcgacg
    21841 gagcgttgct gcgtttgcga caccatacgc agcagctggg aatgcggctg gtgctggatg
    21901 gcgtgtttaa ccacagtggc gattcccatg cctggtttga caggcacaat cgtggcacgg
    21961 gtggtgcttg tcacaacccc gaatcgccct ggcgcgactg gtactcgttt agtgacgatg
    22021 gcacggcgct cgactggctg ggctatgcca gcttgccgaa actggattat cagtcggaaa
    22081 gtctggtgaa tgaaatttat cgcggggaag acagtattgt ccgccactgg ctgaaagcgc
    22141 cgtggaatat ggacggctgg cggctggatg tggtgcatat gctgggggaa gcgggtgggg
    22201 cgcgcaataa tttgcagcac gttgccggga tcaccgaagc ggcgaaagaa acccagccgg
    22261 aagcgtatat cgttggagag cattttggcg atgcacggca atggttacag gccgatgtgg
    22321 aagatgccgc catgaactat cgtggcttca cattcccgtt gtggggattt cttgccaata
    22381 ccgacatctc ttatgatccg cagcaaattg acgcccaaac ctgtatggcc tggatggata
    22441 attaccgcgc cggactttct catcaacagc aactgcgtat gtttaatcag ctcgatagcc
    22501 acgatactgc gcgatttaaa acgctgctcg gtcgggatat tgcgcgcctg ccgctggcgg
    22561 tggtctggtt gttcacctgg cctggtgtac cgtgcattta ttacggtgat gaagtgggac
    22621 tggatggtaa aaacgatccg ttttgccgta aaccgttccc ctggcaggtg gaaaagcagg
    22681 atacggcgtt attcgcgctg taccagcgaa tgattgcgct gcgtaagaaa agtcaggcgc
    22741 tgcgtcgtgg cggctgtcag gtgctgtatg cggaagataa cgtggtggta tttggccgcg
    22801 tgctgaatca gcagcgtgta ctggtggcaa tcaaccgtgg agaagcctgt gaagtggtgc
    22861 tacccgcgtc accgttgctt aatgttgcgc aatggcaacg caaagaaggc catgggcaac
    22921 tgacagacgg gattctggct ttgcctgcca tttcggctac ggtgtggatc aactaaagca
    22981 tctgttttat ttattacgtc gtagtcacca gccctgacac tacgcagcgc aaaaaagctg
    23041 ctcaatgtca gggctgagtt tgttaaatat ttgtcccgtt cgatatgagc gatttttggt
    23101 attctttgcc catgaggtta tgtacaacat gctccaggat aaccctgtag tggagcaaag
    23161 atatgacaat ttcaaattcg aatttattaa aaccgtttat tactggtact gagttgccac
    23221 cttttaaaga ggatgttttt tctaaaacag aagaacaatt taaaaaaagc ccccatggca
    23281 aattgctttt catttccgga aatgaaaact tagtaaacat ttcagcggaa aaaatcgatg
    23341 aaataaaaaa tagcaaagat ttcttttcaa acattgtaaa tataataatt ttactcatta
    23401 agcatcctga taaaattctg cccattcttc atggttgtcc tgcagagtcc atcgaactca
    23461 ttaagaatgc gaaacgaacg gggcaatggt catatgagat gactgataag aacgggcaga
    23521 atattgaagt gtcctatatt ttcactgata ccatagatga taaatctgat ggaaaattat
    23581 gcttaaaaat ctgtaactct tgcaaccaaa atgattctag tacacatgaa tataaaatag
    23641 atcatcaaca gttgaaaaat cacataaggc aacttgagga gtgggccctt cttgaaaagt
    23701 tttatgataa caacgcttat tattctaaac gtacaaaaca attagagaag aaaattgccg
    23761 atgcggggtt tataacaggg aaggttaatg ccgataactt taatgtaaaa gagtttaaag
    23821 acgatatagc ctcgatgctt tgtgaacagc cccccatgcg tacacaccag atttcttcat
    23881 ccggatactt atctgccgat aaagtgcctg atctctataa gacaaatttg aaagacgcgc
    23941 agagagatct gaaaacaaca tcggttgaca tcgatggtgt tagtctaaaa tcaaaaactc
    24001 gggaaaaaat tgcggaaaaa attgcgaaaa aaactgagga aaaaattgcg aaacaaaatg
    24061 cgaagaccat tgaggagaag aatagtgaaa aaaacaagaa agaaacaaat cctgaggata
    24121 attttgtctt aaaattctca ccggaagaaa tcaatgagat gctcctggat tacagcgatg
    24181 aagaacaaaa aaaattaaga ccttttttca ctagtgatca catctattgt ttgtttgatg
    24241 cttttagtca gggtttgcat aatgttgctc gtaatggcag tccacggtat acaggtttac
    24301 tacatcaaat agcatccaac tctgagatat tacaagattt tgatcaacaa ttgttctggc
    24361 gcacgttttc aggaggagtc ttccatcgac gtatctctgt gaacagcgag ccagaaaaga
    24421 cagatgtatg gcgattcagt acacaatttg attttccaca tataaatgac aacggagagt
    24481 tgtccagaac ggtactcatg ttcgaggggg ttgctgaaag caactttaaa gatatcgcca
    24541 atcattccag cgaatgtttt tcttacagtt gttatgccgc tccgctggat gcgaatgcta
    24601 aaaaatagtg acgccggagc ttgaagtttc agagcgcctt gcgtgacgcc tgcgccatca
    24661 tccgcggata aaactgccag aagcgggttt cgagggcggc ataatgtgcg tttaaatcgt
    24721 accaggagtc acgcagggca tccagacgtg ggcgacggct tgccatgccg tttaacacgt
    24781 tctggatgaa atccatatcg cgatagcgca ccagccactg ctctgaccac aagtaattgt
    24841 tcagattgat aaaacgtggc ggtgagtccg gcaaaatcgt catcacttgc tcgcgggcat
    24901 aacagacaaa ttcctgtagc ggaaagtccg gcgacagctg cgaccagtgg cgggaaagaa
    24961 agtgatccca catgacatcc agcgtaatag gcgcaacgcg gcgcgtttca ctacgaaacc
    25021 attcccgtgc ttcgcggact tccggcagat tgtcggttag tacatcaatg cgccgatgca
    25081 tatgaatgcc agccacgacg tcgggcggaa aactttcttc aggatttccg cgtacgaaat
    25141 cagccagtaa attgccggaa agcgagcttt ccgcgagatg ggctaaatgc aggtgagcta
    25201 aaaaattcat cgattatatt ctatccaaag gggggtaaag gttgcaggga gagcgccccg
    25261 gcactagact acccgcctct tattttagtc tgagtcagtg tcatgcgcgt taccgatttc
    25321 tcctttgaat tgcccgaatc cctgattgcc cactatccca tgcctgaacg cagtagctgt
    25381 cgtttactgt cgctggacgg gccgacgggc gcgctgacgc acggtacttt caccgattta
    25441 ctcgataagc tcaaccccgg cgatcttctg gtttttaata atacccgcgt gatcccggcg
    25501 cgtctgtttg ggcgtaaagc cagcggcggc aagattgaag tgctggttga gcggatgctc
    25561 gacgacaaac gcattcttgc gcatattcgc gcctcgaaag cgccaaaacc tggcgcagaa
    25621 ctgttgctgg gcgatgacga aagtattaac gcaacaatga ccgcgcgcca cggcgcactg
    25681 tttgaagtcg aatttaatga tgatcgttcg gtactggata tcctcaacag catcggccat
    25741 atgccgctgc cgccgtatat cgaccgtccg gacgaagacg ctgaccgcga actttatcaa
    25801 accgtttata gcgaaaaacc gggcgcggtt gcagccccga ccgctggtct gcattttgac
    25861 gaacctttgc tggaaaaatt acgcgccaaa ggcgtggaga tggcgtttgt caccctgcac
    25921 gttggtgcgg gcaccttcca gccggtgcgc gtcgacacca ttgaagatca catcatgcac
    25981 tcggaatacg ctgaagtacc gcaggatgtg gtagacgcgg tactggcggc gaaagcgcgc
    26041 ggtaaccggg tgattgcggt tggcaccacc tcggtacgtt cgctggaaag cgcggcccag
    26101 gcggcgaaaa acgatctcat cgaaccgttc tttgacgata cccaaatctt tatctatccc
    26161 ggcttccagt acaaagtggt cgatgcgctg gtgacgaact tccaccttcc tgaatcgacg
    26221 ctgattatgc tggtttcggc atttgccggc tatcaacaca ctatgaacgc ctataaagcg
    26281 gcggtagaag agaaatatcg cttttttagt tacggtgatg cgatgtttat cacgtacaat
    26341 ccgcaggcaa ttaatgagcg cgtcggggag taattccgcg gcgctggttt aaacgttgga
    26401 ctgtttttct gacgtagtgg agaaaaaatg aaatttgaac tggacaccac cgacggtcgc
    26461 gcacgccgtg gccgcctggt ctttgatcgt ggcgtagtgg aaacgccttg ttttatgcct
    26521 gttggcactt acggcaccgt aaaagggatg acgccggaag aagttgaagc cactggcgcg
    26581 caaattatcc tcggcaacac cttccacctg tggctgcgcc cgggccagga aatcatgaaa
    26641 ctgcacggcg atctgcacga ttttatgcag tggaaaggac caatccttac cgactccggc
    26701 ggcttccagg tcttcagcct tggtgatatt cgtaaaatca ccgaacaggg cgttcatttc
    26761 cgtaacccga tcaacggcga cccgattttc ctcgacccgg aaaagtcgat ggagattcag
    26821 tacgatcttg gttcggatat cgtcatgatc tttgatgagt gtacgccgta tcctgctgac
    26881 tgggattacg caaaacgctc catggagatg tctctgcgtt gggcgaagcg tagccgtgag
    26941 cgttttgaca gtctcggaaa caaaaatgcg ctgtttggta tcattcaggg cagcgtttac
    27001 gaagatttac gtgatatttc tgttaaaggt ctggtagata tcggttttga tggctacgct
    27061 gtcggcggtc tggctgtggg tgagccgaaa gcagatatgc accgcattct ggagcatgta
    27121 tgcccgcaaa ttccggcaga caaaccgcgt tacctgatgg gcgttggtaa accagaagac
    27181 ctggttgaag gcgtacgtcg cggtatcgat atgtttgact gcgtaatgcc aacccgcaac
    27241 gcccgaaatg gtcatttgtt cgtgaccgat ggcgtggtga aaatccgcaa tgcgaagtat
    27301 aagagcgata ctggcccact cgatcctgag tgtgattgct acacctgtcg caattattca
    27361 cgcgcttact tgcatcatct cgaccgttgc aacgaaatat taggcgcgcg actcaacacc
    27421 attcataacc ttcgttacta ccagcgtttg atggcgggtt tacgcaaggc tattgaagag
    27481 ggtaaattag agagcttcgt aactgatttt taccagcgtc aggggcgaga agtaccacct
    27541 ttgaacgttg attaatatta ataatgaggg aaatttaatg agctttttta tttctgatgc
    27601 ggtagcggca acgggtgcac cggcgcaagg tagcccgatg tctttgattt tgatgctggt
    27661 ggtattcggt ctgattttct atttcatgat cctgcgtcca cagcagaagc gcaccaaaga
    27721 acacaaaaag ctgatggact ccattgccaa aggtgatgaa gttctgacga acggtggcct
    27781 ggttggtcgc gtaaccaaag tagcggaaaa cggctacatt gctatcgcgc tgaatgacac
    27841 cactgaagta gttattaaac gtgacttcgt agctgccgtc ctgccgaaag gcaccatgaa
    27901 ggcgctgtaa ttaaaatttt tccctaaggg aattgccgtg ttaaaccgtt atcctttgtg
    27961 gaagtacgtc atgctgatcg tggtgattgt catcggtctg ctgtatgcgc ttcccaacct
    28021 gtttggtgag gatccggctg ttcagatcac tggtgcgcgc ggagtcgccg ccagtgagca
    28081 aacgctgatc caggtccaga aaacgttaca agaagaaaaa ataactgcta agtctgtggc
    28141 actggaagag ggcgctattc ttgcgcgctt cgactccact gacacccagc tgcgcgctcg
    28201 tgaagcatta atgggcgtta tgggtgacaa atacgtcgtg gcgcttaacc ttgccccggc
    28261 aacgccgcgc tggctggcag ctattcatgc tgagccgatg aagctcggcc ttgacctgcg
    28321 tggcggcgtt cacttcctga tggaagtgga tatggacacc gcgcttggca aactccagga
    28381 acaaaacatc gatagcctgc gcagcgacct gcgtgaaaag ggcatcccgt ataccaccgt
    28441 tcgtaaagaa aacaactacg gcctgagcat cactttccgc gatgctaaag ctcgtgatga
    28501 agccattgcg tatctgagca agcgccatcc ggacctggtg attagcagcc agggcagcaa
    28561 ccagctgcgt gcggtaatga gcgatgctcg cctgagtgaa gcgcgtgaat atgcggtgca
    28621 gcagaacatt aatatcctgc gtaaccgtgt aaaccaactt ggcgtggcgg agccggtggt
    28681 tcagcgtcag ggtgctgacc gtatcgttgt tgaactgcca ggtattcagg acaccgcgcg
    28741 tgcgaaagag attctgggtg cgacggcaac gctggaattc cgtctggtaa acaccaacgt
    28801 tgatcaggcc gctgcggcat ccggccgcgt accgggcgac tctgaagtga aacagacccg
    28861 cgaaggtcag ccggttgtgc tgtacaaacg cgtaattctg accggtgacc atatcaccga
    28921 ctccacttcc agccaggacg aatacaacca gccgcaggtt aacatttcgc tcgacagcgc
    28981 aggtggcaac attatgtcta acttcaccaa ggacaacatc ggcaaaccga tggcgaccct
    29041 gtttgtggag tacaaagaca gcggcaagaa agatgctaac ggtcgtgcgg ttctggtgaa
    29101 acaggaagag gtgattaaca tcgctaacat ccagtctcgt ctgggtaaca gcttccgtat
    29161 caccggtatt aacaacccga acgaagcccg tcagctttca cttttgctgc gtgccggtgc
    29221 gttgatcgcg ccaattcaga ttgttgaaga acgtaccatt ggcccgactc tgggtatgca
    29281 gaacattgaa caggggctgg aggcttgcct tgccggtctg ctggtttcta ttctgtttat
    29341 gatcatcttc tataagaagt ttggtctgat tgcgaccagt gctttgattg ccaacttgat
    29401 cttgatcgtc ggcattatgt cgctgttgcc aggcgcaacg ctgagtatgc caggtatcgc
    29461 gggtatcgtc ttaacccttg cggtagcggt cgacgcgaac gtactgatca acgaacgtat
    29521 taaagaagag ttgagcaacg gacgtactgt tcaacaggca attgatgaag gttatcgtgg
    29581 cgcattcagt tccatcttcg atgcgaacat caccacgctg attaaagtca tcatcctgta
    29641 cgcagtgggt accggggcaa ttaaagggtt cgcgattact accggtatcg gtgtggcgac
    29701 gtcgatgttt accgcgattg tcggtacgcg tgccatcgta aacctgctat atggcggcaa
    29761 gcgcgtcaag aagctgtcaa tctgaggagt gcgatgtggc acaggaatat actgttgaac
    29821 aactaaacca cggccgtaaa gtctatgact ttatgcgctg ggactactgg gctttcggca
    29881 tctctggtct gctgttaatc gccgctatcg ttattatggg cgtgcgcggc tttaactggg
    29941 ggctggattt caccggtggt acggttattg aaattacgct cgaaaaaccg gctgaaattg
    30001 acgtaatgcg tgatgcattg caaaaagccg gttttgaaga gccgatgctg caaaactttg
    30061 gtagcagcca cgacatcatg gtccgtatgc cgcctgctga aggcgaaacc ggcggtcagg
    30121 tgctgggcag ccaggttctg aaggtgatta acgaatccac caatcagaat gcggcagtga
    30181 agcgtattga gttcgtcggt ccgagcgtgg gggcagacct tgcgcaaacc ggtgcgatgg
    30241 cgttgatggc ggcgctgctg tctatcctcg tgtacgtagg tttccgcttt gagtggcgac
    30301 tggcggcagg ggttgttatt gcgctggcgc acgacgttat cattacgctg ggtattttgt
    30361 cgttattcca tatcgagatt gacctgacca ttgtggcatc gttgatgtca gttatcggtt
    30421 actcgcttaa cgacagtatc gtggtatcgg accgtattcg tgaaaacttc cgcaagatcc
    30481 gtcgcggtac gccttacgaa atctttaacg tgtccttgac ccagacgctg caccgtacct
    30541 tgatcacatc cggtactacc ttgatggtta tcctgatgct gtacctcttc ggtggtccgg
    30601 tactggaagg cttctcgctg accatgctta tcggtgtttc catcggtact gcatcttcca
    30661 tctacgtagc atcggcgctg gctctgaaac tgggtatgaa gcgcgaacac atgctgcagc
    30721 agaaagtgga aaaagaaggg gcggatcagc cgtcaattct gccgtaatca agttcccgtt
    30781 gatgttgaaa atcccggtca gaagatcggg attttttttg atgtatggag attgcgaaaa
    30841 tccccgcatc ttgggaaact gcgcgtaacc ctacatttca tccaggtaac ttttcatggc
    30901 tatcatccca aaaaactatg cgcgcttaga aagcggctat cgcgaaaaag cattaaaaat
    30961 ctatccgtgg gtctgcggtc gctgttcccg cgagtttgtt tattccaacc tgcgtgaact
    31021 taccgttcac cacattgatc acgaccatac caataacccg gaagatggca gtaactggga
    31081 attgctttgt ctctattgcc acgatcatga gcattcgaaa tataccgaag cggatcagta
    31141 tggtacgacc gttatcgcag gggaagatgc gcagaaagat gtcggtgaag cgaagtacaa
    31201 cccattcgct gacctgaaag cgatgatgaa caagaagaag tgataaaaaa tgccggatat
    31261 gaaatccggc attctcacaa tcagaagttg taacctacta ccaggtaacc accccagccg
    31321 gtagagcgaa cgttgaagtt gccgttgccg aagttcagtt ctgcatcgtc gttccactga
    31381 ccaccgtcgt gccagtaacg agctacgaca gagtagtgcc aatgatcgta gttcagagcc
    31441 agaatatggc tggaagcgat agagttatta gtacgggtct taataccgtt gattgcgtta
    31501 ccgctgtcat cccctaaatc ggaaccccag tcgaagttgg tgaagccgat gtagctcagc
    31561 tgaccgcccc acagatcggt aatcggcaca aagtatttaa ttttgaaacg gtaaccgtcc
    31621 cactcgtttt cgttcgctgc gccatagttc tgccactggt atttcgcata gacgttcatg
    31681 gacaggctca tcggcaggcc agtatcgata tcggtaccca gacccatgta ccaggtgctc
    31741 tggcgaccat ctttattacg acccatgtcg taaatgtagt tgttcgcgaa gtaccactct
    31801 ttgaacggac caaagctaag gtcagtattg gtcagcttgt cgatggagaa acgtggttcg
    31861 atttccataa acagcggaga accgtggttc cagatacctt ttgcatcgga gttaccgccg
    31921 aagaataccg gcgcatccgc ataaccatag aagtcgaacc agtctttttt agcgaatgct
    31981 tcgtactcaa ggtaggtatc gttgcggatc tgcggtccga aacgggtgtg atagcttccg
    32041 acaacgttaa cgctctggtg ccaccagtcg gaaagatact gcggtttgtc gttttcagct
    32101 gcgttgacag taaaagacga agagagcgcc agtaccgcac cggctgccag taatgttttt
    32161 ttcatatgta tgccactgtt tgaaaatccc ttgcgggagt gaaaaaggcg caaattgcgt
    32221 ttctaaatat ttcgtataca gaggagccta ttataaaaat cattgctcac aaaaatatgt
    32281 ttcgtttcac agttctatca tttacgtaat cgattgcgtt cacgtttaca cacattcggg
    32341 cagggattgt actgactttc acccttgttg caaactttta ctatcaatcc aggtgatgta
    32401 agcggagtaa caaaatgacg gggaagatgt tgcgggacgc acaatatcgc cccgcaatac
    32461 gtttactgca taacaggttg aatgtcgtgg atacgtacaa agcctaactg atccacagac
    32521 atacccttta actgtaacgg aatatcaaca tcgctggggg cgaggacgct ggcaggtgcg
    32581 ttaatcaatt gattctgcac attgatttcc tgaaagttgt ctattgttcc ctgaatttgc
    32641 ccatattcaa cagttccgct gaatgcgggc aagggatcat tcgactcgcc ctgaatacgt
    32701 agcgtcaggg tggtgccatc tgtatcaggc gtaatattca ccagcgacat acgtaaagta
    32761 ccgatctggc tttccagtct tgctggtgtt tttgctccag gcagaaggta aaccccactg
    32821 ctggattttg cattcagcct gttttgctga gtgattttga ccgtttcttt attgagttgc
    32881 gtcatctcct ggttcagcgt gctgacgctg tgtttcatct gtcgcacttc gctttgctgc
    32941 acacaggcgc taaggctgaa caggcttccc agcaggagca gtcgaaaaac gttagtattc
    33001 ataggtcgtc cctttctcgt cgcaattagc ctaatggtag agggtaaaag cagcgaaagc
    33061 atcgatcctt tatctcaaaa gcgttgcgcc tttgttgtat cgtcagttca gggtaaaata
    33121 gatttctgtt aaccacctgg tcaggacgcc gtatgcattg cccattctgt ttcgccgtgg
    33181 acactaaggt aattgactct cgtctcgtgg gcgagggttc atccgtacgc cgccgtcggc
    33241 agtgtctggt gtgtaatgaa cgtttcacca cctttgaagt ggcggagctg gttatgccgc
    33301 gtgttgtaaa aagcaacgac gtgcgtgaac cgtttaatga agagaaattg cgcagcggaa
    33361 tgctgcgggc gctggaaaaa cgtccggtga gttccgatga cgtcgaaatg gcaatcaatc
    33421 atattaaatc gcagctgcgc gccaccggtg agcgcgaagt gccgagcaag atgattggca
    33481 atctggtgat ggagcaattg aaaaagctcg ataaagtcgc ctatatccgt tttgcctctg
    33541 tctaccgcag tttcgaagat atcaaagaat ttggcgaaga gatcgcgcgc ctggaggact
    33601 aagccgtgca ggacgagtat tacatggcgc gggcgctaaa gctggcgcaa cgaggacgtt
    33661 ttaccaccca ccccaacccg aatgtcgggt gcgtcattgt caaagatggc gaaattgtcg
    33721 gtgaaggtta ccaccaacga gcgggtgaac cacatgccga agtacacgca ttgcgaatgg
    33781 cgggtgaaaa agccaaaggt gcgaccgcct atgtcacact cgaaccctgt agccatcatg
    33841 gtcgtacgcc accatgctgt gacgcactca tcgccgctgg cgtagcgcgc gtggttgcag
    33901 cgatgcagga ccccaatccg caggttgctg gacgtggact ttaccgtctg caacaggctg
    33961 gcattgacgt cagccacggg ctgatgatga gtgaagccga gcaattgaat aaaggatttc
    34021 tcaaacggat gcgcaccggc tttccttata ttcaattaaa acttggcgca tcgcttgatg
    34081 gtcgcacggc gatggcgagc ggcgaaagcc agtggatcac ttcgcctcag gcgaggcgcg
    34141 acgtacaacg actgcgcgca caaagtcatg ccattttaac cagcagcgcc acggtgctgg
    34201 cggatgatcc agccttaaca gtgcgttggt ctgaactgga tgaacaaact caggcgctct
    34261 atccgcaaca aaatctccgt cagccgatac gtattgtgat tgatagccaa aatcgcgtga
    34321 cgccggaaca tcgcattgtg cagcagcccg gcgaaacctg gttcgcgcgt actcaggatg
    34381 attctcgtga gtggccggaa acggtgcgta ccttgctgat tccagagcat aaaggtcatc
    34441 tggatctggt tgtactgatg atgcaactgg gtaaacagca aattaacagc atctgggtgg
    34501 aagcggggcc aacgctcgct ggcgcattgc tacaggcggg gttagtcgat gagctgattg
    34561 tctatatcgc acctaaacta ttaggcagcg acgcccgtgg attatgctcg ctgccagggc
    34621 ttgagaaatt agccgacgcc ccccaattta aattcaaaga gatacgtcat gtaggcccgg
    34681 atgtttgcct gcatttagtg ggtgcatgat ctcccggctc gaaagggaag cagcgcacga
    34741 aatattatgc taaaatccgc ccccctgcgg ggccatactc gaacccgaag gaagaaaatg
    34801 aacattattg aagctaacgt tgctaccccg gacgctcgcg tcgccatcac catcgcgcgt
    34861 ttcaacaact ttatcaatga cagcctgctg gaaggtgcaa ttgacgcact gaaacgtatc
    34921 ggtcaggtaa aagatgaaaa cattaccgtt gtttgggtgc ctggtgccta tgagctgccg
    34981 ctggcggcgg gtgcactggc taaaaccggt aaatacgacg cggtgattgc gctgggtacg
    35041 gttattcgtg gtggcactgc ccactttgaa tatgtcgctg gtggtgcaag caacggcctg
    35101 gcgcatgttg cccaggacag cgaaattccg gttgcttttg gggttctgac cactgaaagc
    35161 attgaacaag cgatcgaacg tgctggcacc aaagctggca acaaaggtgc agaagctgca
    35221 ctgaccgcgc ttgaaatgat taatgtattg aaagccatca aggcctgaaa ttagtaaggg
    35281 gaaatccgtg aaacctgctg ctcgtcgccg cgctcgtgag tgtgccgtcc aggcgctcta
    35341 ctcctggcag ttgtcccaga acgacatcgc tgatgttgaa taccagttcc tggctgaaca
    35401 ggatgtaaaa gacgttgacg tcctgtactt ccgtgagctg ctggccgggg tggcgactaa
    35461 caccgcatac ctcgacggac tgatgaagcc atacctgtcc cgcctgctgg aagaactggg
    35521 ccaggtagaa aaagcagtac tgcgcattgc gctgtacgag ctgtctaaac gtagcgatgt
    35581 gccatacaaa gtggccatta acgaagcgat cgaactggcg aaatcgttcg gcgcagaaga
    35641 cagccataag ttcgtcaacg gcgtactcga taaagcagca cctgtgattc gccctaacaa
    35701 aaagtgatat ccaggccggt agattcacgg aagaccgttc cgcgatcgcc ggccttttct
    35761 tttttacctg ctgaggcata acgtatggca tgtggcgagt tctccctgat tgcccgttat
    35821 tttgaccgtg taagaagttc tcgtcttgat gtcgaactgg gcattggcga cgattgcgca
    35881 cttctcaata tccccgagaa gcagaccctg gcgatcagca ctgatacgct ggtggcgggc
    35941 aaccacttcc tccctgatat cgatcctgct gatctggcat ataaagctct ggcagtgaat
    36001 ttaagcgatc tggccgcgat gggggccgat ccggcctggc tgacgctggc attaacctta
    36061 ccggacgtcg acgaagcgtg gcttgagtcc ttcagcgaca gtttgtttga tcttctcaat
    36121 tattacgata tgcaacttat tggcggcgat accacgcgtg ggccattatc aatgacgttg
    36181 ggtatccacg gctttgttcc gatgggacga gccttaacgc gctctggggc gaaaccgggt
    36241 gactggatct atgtgaccgg tacaccgggc gatagcgccg ccgggctggc gattttgcaa
    36301 aatcgtttgc aggttgccga tgctaaagat gcggactact tgatcaaacg tcatctccgt
    36361 ccgtcgccgc gtattttaca ggggcaggca ctgcgcgatc tggcaaattc agctatcgat
    36421 ctctctgacg gtctgatttc cgatctcggg catatcgtga aagccagcga ctgcggcgca
    36481 cgtattgacc tggcattgct gccgttttct gatgcgcttt ctcgccatgt tgaacctgaa
    36541 caggcgttgc gctgggcgct ctctggcggt gaagattacg agttgtgttt cacggtgccg
    36601 gaactgaacc gtggcgcgct ggatgtggct ctcggacacc tgggcgtacc gtttacctgt
    36661 atcgggcaaa tgaccgccga tatcgaaggg ctttgtttta ttcgtgacgg cgaacctgtc
    36721 acgttagact ggaaaggata tgaccatttt gccacgccat aaagatgtcg cgaaaagtcg
    36781 cctgaagatg agtaatccgt ggcatctgct tgctgtcgga ttcggaagtg gattaagccc
    36841 aatcgttcct ggcacgatgg gatcgctggc ggcgattccg ttctggtatc tgatgacctt
    36901 tttgccctgg cagctctatt cgctggtggt gatgctgggg atctgtatcg gcgtctatct
    36961 ttgtcatcaa acggcgaaag acatgggcgt gcacgatcac ggcagcattg tctgggacga
    37021 atttattggt atgtggatca cgctcatggc gctgccgacc aatgactggc agtgggtcgc
    37081 cgccgggttt gtgattttcc gtatcctgga tatgtggaaa ccgtggccga tccgctggtt
    37141 tgaccgcaat gtacatggcg gcatggggat catgatagat gatattgtcg ccggggtgat
    37201 ttccgcaggc atcctgtact ttattggaca tcactggccg ctgggtattc tgtcgtagtt
    37261 gtgcaccgat gcctgatgtg acacttgtca cgtctcatca ggcctgcata cctatttaaa
    37321 tcctacgacc ggatgcggtt tatacggcgt ttccagttca gcaatctgtt ccggctttaa
    37381 agtgatatcc accgcgttca acagctcatc aagctgttcc tcccgagaag ttccgataat
    37441 cggtgcggca atgcccggtt tactcaacaa ccaggccagc gcaacttgtg ctcgtgttgc
    37501 accgagttct tcactgacgc ccgttaaccg ctctgcgatc tgcgcgtcat tttcatcgct
    37561 ttctttatag agatttttac ccacctcatc agacaccagt cgtgcggtgg tttctcccca
    37621 aggacgcgtc aggcggcccc gcgccagcgg gctccacgga atgaccgcca cgccttcctc
    37681 ataacacagc ggcagcatct cgcgctcttc ttcacgataa atcagattgt agtgatcctg
    37741 catactgaca aactgcgccc agccgtgctg tttttgtagt tccagtgctt gagcaaactg
    37801 cgaagcgtgc atggatgacg cgccgatata acgcgctttc ccggctttta ccacgtcgtt
    37861 gagggcttcc agcgtctctt cgatcggcgt gttgtaatcc cagcgatgaa tttgcaggat
    37921 atcgacataa tccatgccga gacggcgcag gctgtcgtcg atagagcgca aaatttgtgc
    37981 acgggataat ccttccggta aatcaccaac gcgatggaac actttggtcg caacgaccac
    38041 gtcttcacga cgggcgaaat cccgcagtgc gcgaccgacg atctcttcgc tgctgccatc
    38101 ggaatagcta ttggcggtat caaagaaatt tatgccgcct tccagcgcgc gtttaatgat
    38161 gggacggctg ctttcttccg gcagtgtcca tgcgtgatta ccgcgatctg gctcgccaaa
    38221 ggtcatacag ccgaggcaaa gtcgggaaac gcgaaggtcg gtttttccta agggcttgta
    38281 ttgcatgctg ccactcctac catgaataat ttcttaagca tagcaggagt ggagtaggga
    38341 ttatgccagc caggccttga ttttggcttc cataccggcg gcatcgaggc cgagttcggc
    38401 gcgcatttct tcctgtgttc cttgtggaat aaagaagtcc ggcagaccaa tgttcagcac
    38461 gggtactggt ttacgatggg ccatcagcac ttcgttcacg ccgctgcctg caccacccat
    38521 aatggcgttt tcttctacgg taaccagcgc ttcatggctg gcggccattt ccagaattaa
    38581 cgcttcatca agcggtttca cgaaacgcat atcgaccagc gtagcgttca gcgattcagc
    38641 gactttcgcc gcttctggca tcagcgtacc aaagttaagg atcgccagtt tctcaccacg
    38701 acgcttcaca atgcctttgc caattggcag tttttccagc ggcgtcaatt ccacgccaac
    38761 cgcgttgccg cgcgggtagc gcaccgcgga cgggccatcg ttatagtgat agccggtata
    38821 gagcatctgg cgacattcgt tttcatcgct cggggtcata atgaccattt ccggtatgca
    38881 gcgcaggtaa gagagatcaa aagcgccctg gtgggtttga ccgtcagcac caacaatgcc
    38941 cgcgcggtcg atggcgaaca ggaccgggag tttttgaatc gccacgtcat gcaacacctg
    39001 atcataggca cgttgcagga aggtggagta aattgccacg atcggtttgt agccaccaat
    39061 cgccagaccg acggcaaagg tcaccgcgtg ttgctcggca atcgctacat caaaatagcg
    39121 atccgggaat ttacgtgaaa actcgaccat gccggaacct tcacgcatcg ccggagtaat
    39181 cgccatcagc ttgttgtctt tcgctgccgt ttcgcacaac cagtcgccaa agatttttga
    39241 atagctcggc aaaccgccgc tacttttcgg caaacaaccg ctggagggat caaatttagg
    39301 cacggcgtgg aaggtgattg ggtctttttc tgccggttca taaccacgac cttttttagt
    39361 catgatatgc aggaactgcg ggcctttcag gtcgcgcatg ttcttaagcg tggtgataag
    39421 ccccagcaca tcgtgaccgt ccaccgggcc gatgtagtta aagcccagct cttcaaacaa
    39481 cgtgccaggc actaccatgc ctttaatatg ttcttcggtg cgtttgagca gctctttaat
    39541 ggggggcacg ccagagaaaa cttttttccc gccttcgcgc agtgaagagt aaagcttacc
    39601 ggaaagcagt tgcgccagat ggttgttgag cgcgccaaca ttttcggaaa tcgacatttc
    39661 attgtcgttg agaaccacca gcatatcagg acggatatcg cccgcgtgat tcatcgcttc
    39721 aaacgccatg ccagcggtaa tcgcgccatc gccaatgaca cagacggtac ggcgattttt
    39781 gccttctttc tcggcagcaa ccgcaatacc aattccggca ctgatggagg ttgatgaatg
    39841 cccgacgctt aatacgtcat attcgctttc gccgcgccac gggaacgggt gcaggccgcc
    39901 tttctgacgg atggtgccga ttttgtcgcg gcgtccggtc aaaattttat gcggataagc
    39961 ctgatgcccc acatcccaga ttaactggtc aaacggggta ttgtagacat agtgcagcgc
    40021 cacggtcagt tcgaccgtgc ccagcccgga ggcgaagtgc ccgctggaac ggctcacgct
    40081 gtcgagtaaa tagcggcgca gttcgtcgca gagtttcggt aaactctctt tcggcaacag
    40141 tcgtaactcc tgggtggagt cgaccagtgc cagggtcggg tatttggcaa tatcaaaact
    40201 catcaggggc ctattaatac ttattgttta tttattacgc tggatgatgt agtccgctag
    40261 cgcttccagt gccgaggtat cgagtgactg ttcagccagt tgtttcagcg actgacgggc
    40321 atcgtcgatc agatcccggg ctttcttccg ggcttgctca agacccagaa gtgcagggta
    40381 ggtactttta ccaagttgct gatcggcacc ctggcgtttt cccaacgttg cagtatctcc
    40441 taccacatcc aggatgtcat cctgaacctg gaaggcaagg ccgatgctct ctgcgtactt
    40501 gtcgagtact ggcagagcac gacgcccttt atctccggcg cttaatgcac caaggcgaac
    40561 ggcggcgcga atcaatgcgc cagttttatg acgatgtata cgctcaagcg cgtccagagg
    40621 tacgcgtttg ccttccgcgt ctaaatctaa tgcctgacca ccgcacattc cggcaatacc
    40681 gctggcgctc gccagttcag aaatcatcga aattctgtcg cgatccgaca cttccggcat
    40741 atcagcatcg cttaaaatcg agaacgccag cgtttgtaaa gcatcgccag cgagaatcgc
    40801 gtttgcttcg ccaaacttca catggcaggt cggcaaaccg cgacgcagat cgtcatcatc
    40861 catcgccggt aaatcatcat gaattaatga gtaagcgtgg atacactcta cggcggcagc
    40921 gggtgcgtcc agtgtgtttg tgctaacgcc gaacatatga ccagtggcat aaaccaggaa
    40981 aggtcgcaga cgcttaccac ctaataatgc gccatactgc atggtttcga ccacgggagt
    41041 gttctgaaag ggcagtgggg cgataaaacg gctcagcgcc tggttggcct gcttaacgca
    41101 ggcttcgagt tgctgcggaa agtccattac tcattgtccg gtgtaaaagg ggttagagag
    41161 gcatcttcat tgtcagacag cagaatttgt acgcgctgtt cggcttgttg taatttggcc
    41221 tgcccctgac gtgccagctg cacgccgcgt tcgaactcgt tcagcgcctc ttccagcggc
    41281 aggtcgccac tttccagacg ggttacaatc tgttccagct cgctcagcgc cttttcaaag
    41341 ctggcgggag cctcattttt cttcggcata atgaatgtct gactctcagt atttttcgcc
    41401 ccgtcatggt aacggactca gggcaaatag caaataacgc gcaatggtaa ggtgatgtgc
    41461 gcagcaaagc gatgttagtg gtatacttcc gcgcctggat gcagccgcag gtgtgggctg
    41521 ctgtattttt ccctatacaa gtcgcttaag gcttgccaac gaaccattgc cgccatgaag
    41581 tttatcatta aattgttccc ggaaatcacc atcaaaagcc aatctgtgcg cttgcgcttt
    41641 ataaaaatcc ttaccgggaa cattcgtaac gttttaaagc actatgatga gacgctcgct
    41701 gtcgtccgcc actgggataa catcgaagtt cgcgcaaaag atgaaaacca gcgtctggct
    41761 attcgcgacg ccctgacccg tattccgggt atccaccata ttctcgaagt cgaagacgtg
    41821 ccgtttaccg acatgcacga tattttcgaa aaagcgttgg ttcagtatcg cgatcagctg
    41881 gaagggaaaa ccttttgcgt acgcgtgaag cgccgtggca aacatgattt tagctcgatt
    41941 gatgtggaac gttacgtcgg cggcggttta aatcagcata ttgagtccgc gcgcgtgaag
    42001 ctgaccaatc cggatgtgac tgtccatctg gaagtggaag acgatcgtct tctgctgatt
    42061 aaaggccgct acgaaggtat tggcggtttc ccgattggta cccaggaaga tgtgctgtcg
    42121 ctcatttctg gtggtttcga ctccggcgtt tccagttata tgttgatgcg tcgcggatgt
    42181 cgtgtgcatt actgcttctt taaccttggc ggcgcggcgc atgaaattgg cgtgcgtcag
    42241 gtagcgcatt atctgtggaa ccgctttggc agctcccacc gcgtgcgttt tgtcgctatt
    42301 aatttcgaac cggtcgtcgg ggaaattctc gagaaaatcg acgacggtca gatgggcgtt
    42361 atcctcaaac gtatgatggt gcgtgccgcg tccaaagtgg cagaacgtta cggcgttcag
    42421 gcgctggtta ccggtgaagc gctcggccag gtgtccagcc agacgctgac caacctgcgc
    42481 ctgattgata acgtctccga tacgctgatc ctgcgtccgc tgatctctta cgacaaagag
    42541 cacatcatca acctggctcg ccagattggc accgaagact ttgcccgcac gatgccggaa
    42601 tattgcggcg tgatttccaa aagcccgacg gtgaaagcgg ttaaatcgaa gattgaagcg
    42661 gaagaagaga agtttgactt cagcattctc gataaagtgg ttgaggaagc gaataacgtt
    42721 gatatccgcg aaatcgccca gcagaccgag caggaagtgg tggaagtgga aaccgtcaat
    42781 ggcttcggcc cgaacgacgt gatcctcgat atccgttcta tcgatgaaca ggaagataag
    42841 ccactgaaag tcgaagggat tgatgtggtt tctctgccgt tctataaact gagcaccaaa
    42901 tttggcgatc tcgaccagag caaaacctgg ctgttgtggt gtgagcgcgg ggtgatgagc
    42961 cgcctgcagg cgctctatct gcgcgagcag ggctttaaca atgtgaaggt gtatcgcccg
    43021 taatatgtgg ttgtaacgtc gcatctggtc agatgcgacg tttaccgcat ccgacactac
    43081 tcgtaataat tataaatccc tgccgccatc accagttgtg atgccacttc atgggctttc
    43141 tcgcgcccaa ccagcagatc gataattttc agaccaaagt cgatagctgt acccggcccc
    43201 tggctggtca gcaattttac tcgtgcatcc cagacgacgc gcttgtcctg ccattgttcg
    43261 gcgggaattt tgtctttcag cgtcgggaag ccggtcatat tgccaatcgg gaagatatcg
    43321 tgcgggacca gcacggtggc tggcgcggcg caaatagccg cgacgatacg cccggaacgg
    43381 tggaactgtt taacggtttc aaccagcagg gtgctatcgc gaaaacactc tgcgcctttg
    43441 atgccaccag gcagcacaat cacgtcatat tcgccatcag ccacttcgac cagcggcgca
    43501 tccgccagca tctttacgcc gcgcgagcag gtaattgcca ggttaccatc gctggcgacg
    43561 ctggcagtgg tgactttgat accgccgcga accaagaggt cgatagtggt gacggcttca
    43621 gtctcttcac taccaggggc gaggcaaacc agtgccgatg cgctcatatt cactctcctt
    43681 tctttttacc atttcaaaca ggcgggtgtt ttccggtacg gcaatcccat gcgcgcgggc
    43741 gcggcgtaag agaaaaccat tgatatagtc gatttcggtg tggcgcagcg cgcggatatc
    43801 ctgcaacatc gacgagatat tttccgctgt ggcatcaatc acctgcatca cgtaatcacg
    43861 caaatcttct gctgaagtat gatgcccttc gcgttcgatc actgccgcga cttcttcgca
    43921 tatctgcata atttcttgcg gatgatgacg taattcacca ttcgggcaat tccagatggc
    43981 ggtcagtgga ttaatcacac agttgactgc cagcttgcgc cacagctcgg cgcgaatatt
    44041 gttatgccac gcgacgtcag gcaatacggt ttgcaaaata tccgccagat aactgtaatc
    44101 gccgtcctgt tgccgtgccg gaccaatatg cgtgataccg tttgccacat gaataatgac
    44161 attgccgtcg cggcgggcgg catgggtggt ggtgcccatc agtaatggct gctgaatgtt
    44221 ttgcaactct tcgatggtac ccatgccgtt gtgaattaac agtattggcg tggttacagg
    44281 cagtgtggac gcgaggcttt tgacggcatc ggaaacctgc catgctttca gcgtcaccag
    44341 gagcagatcg ctggtggcga gaaaatcggg atcgttggcg gtcagcgatt cgttaaatat
    44401 cgaaccgtca gtctcaacca gattcacgct acaataaggt tgcggtacgc gcagccagcc
    44461 ctgaacgtcg tgaccctgtt tacaaagtgc tgtaagccat aattgcccta aggcaccgca
    44521 tcccaatacg gtaattttca ttgttcctcc tcacccgcaa ccactccggg tgttcaataa
    44581 ggctatccct taattgtgca tgctgttgcg actatgcaca attaagggat acgtcctggt
    44641 gcaggactgt tggttattta actttgcagg tattatgctt cgcatcaaaa atgaagggag
    44701 aggaaaagat gccatctttc gatattgtct ctgaagttga tcttcaggaa gcacgtaacg
    44761 cggtcgataa cgcgagccgc gaagtggagt cccgttttga cttccgtaat gttgaagcct
    44821 catttgagct gaacgacgcc agcaaaacca tcaaagtgtt gagcgagtcc gacttccagg
    44881 tcaatcagtt gctggatatt ctgcgtgcca agctgctgaa gcgcggcatt gaaggcagtt
    44941 cactggatgt accggaaaat atcgttcata gcggtaaaac ctggtttgtg gaagcgaaac
    45001 tgaaacaggg cattgagagc gcgacccaga agaaaatcgt caagatgatt aaagacagca
    45061 aactgaaagt gcaggcgcaa attcagggcg atgagatccg tgtaacgggt aaatctcgtg
    45121 atgatttgca ggctgtcatg gcgatggtac gtggtggtga tctcggtcag ccgttccagt
    45181 tcaaaaactt ccgcgattaa tcgcgacaat gtgcgttttg ttcatgtcag atgcggcatg
    45241 aacgcctgat tcggcttaca aaggtttgta actcaggaac ttagtaggcc tgataagcgt
    45301 agcgcagcag gcaatttcgc ctcgctttta tgcctggcga attgcctgtt caacctcaaa
    45361 gcgattcgtc actttgctgt cgattttcac atacgctgaa tgttcttctt ctgcaatcaa
    45421 cacttctttg acgccttcag tttccagcaa acgcactttt aacgcattgt ttgcggcaat
    45481 gtccgccggg atttcaatgc gcaagctgct gacatacggt ggttctttca tggtactggc
    45541 gactgccagc cacactgcgg ccagcattgc gccagcgaga aatactccct gaccgtcaaa
    45601 catgccgtca atccagccgc ccagcgaacc gccaatcgcc acgccaagaa actggctggt
    45661 ggagtaaaca cccatcgccg tacctttgta acctgctggc gattctttac tgataagtga
    45721 aggcagaagg gcttccatca aattaaacgc cacaaagaaa agctgcacgc cgaccaccag
    45781 ttgccagaac tgcgtttgtg cgttccacaa cacaatttcc gcgaccacga tcaacccgac
    45841 gcaaaagaca aagacttgct tcattttgcg cttaacttca gcgtagataa tgaaaggcac
    45901 gaccgagcca aaggcgatta acatcgttgc caggtagacc ttccagtgtt cagccgccgg
    45961 gaaccccgca tcagccatct gtccgggcag ggcaacaaag gtcgacatca gcaaaatatg
    46021 cagacacata atgccaaagt tgagtttcag cagccgcggt tcagccagca ctttactgaa
    46081 actgcctttc accattccgg actcacgatt aagtacgtga gtgctactgt tgggcacaac
    46141 ccaaatggtc aacgcaatgc cggttgttgc cagaatagcg atcatccaga acagcgcgtg
    46201 cagcccaagt ttgtgagtga tgatcgggcc aagcaccatc gcaatggcaa aggtaatgcc
    46261 aaagctcacg ccgataaacg ccatcgcttt ggtgcggttt tgttcgcgcg taagatcaga
    46321 aagtagtgcc ataacggcag cggcaatcgc tccagaacct tgtaacgccc ggcccagaat
    46381 aattccccag atggagtcgg agagcgcagc aataacgcta ccggcggcaa acaccgccag
    46441 cccaccgaca attaatggtt tgcgaccaat gcggtctgaa agcaggccaa acggaatctg
    46501 aaaaacggcc tgagtcagac cataaatacc aatggcaata ccgattaatg cttcgctggc
    46561 accttgcaga gccatgccgt acgtggtcag aaccggcaga accatgaaca tgcccagcat
    46621 gcgcaacgag aaaacggtgc ctaaacccca ggtcgcgcgc cgctcacctg gcgtcatttt
    46681 ataatcgttc attaccacct ctgttttaaa ttcgcgacta gtgtaaagcg gcaaacgaat
    46741 ggggtaaaca tgcggatttt ttagtaaata tttcgagagg gatatgattc taatgctaag
    46801 aaaaaaggtg ccgtagcacc tttttaactg agaggttgtg ttaccacaca gcagccagca
    46861 gcgtatgcga gtccggcacc ataaaatcaa cggacatcat taccgagagg gcagtgatgg
    46921 cgatgataga gaagccgaac agcttgcgcg cccagattcg atcatcagca actttataac
    46981 cgcgcagggc catacctaac caccagacgc tcaccgccgc ggcgaccacc agatatttat
    47041 acccagcgta accgccaaga gagagcatca gcgtggcaac ggcaaaggcg atgatataca
    47101 gcgtgatgtg attcttcgcc accgaaatgc cttttaccac tggcaatacc ggaatgtttg
    47161 ccgcttggta atccttaaag cggaaaatgg cgatggcata ggagtgaggc atctgccaca
    47221 ggctgaagat agccagcagg atcgctgcgc cgctatcgaa ctcgccggtt accgcacagt
    47281 agccaatcac cggcggcgca gcgcctgaga gcgaaccaat caatgtgccg tagactgagt
    47341 ggcgtttcat gtacaggcta taaacgccga cataaaccac aaagcccatc acccccagcc
    47401 agcaggccag cggattcgcg ccaaaccaca gcagcataaa gccagcaata cccagcaagg
    47461 tggcgtacac cagcgagaca gcaggagaga tcaggccttt aaccagcacc cgattcttcg
    47521 tcctttccat ctttctgtcg atatccctgt cgatgtagtt gttaaacaca caacccgacg
    47581 ccacaaccag tgacacccca accagcgtgt agataaacag gggataatca atgctgccct
    47641 ttgaggccag caggaatccc ccaatcaccg agatcaggtt gccaaagatg atgcctggtt
    47701 tcgttacttg caggtattgc ttaaacatca taaccgccgc tcttagtgca tcatcatgtt
    47761 gtagttgagg ttccacataa tccagatgga gcctacaacc aggatagcga tgattagcac
    47821 ggtgaagaca aacgccgtca tgttccagcc ttcatctgat ttggtattca tgtgcaggaa
    47881 gcacaccaga tgcaccagaa cctgtaccac tgccattgcc aggattgttc ccagaattac
    47941 ggccggagag gcagctcctg tcatcaccat ccagaacgga atcaccgtca gaatgatcga
    48001 caggataaag cctgtcatgt aggtttttac gctgccatgg gacgcgccgc tgtgatcggt
    48061 agaatgactc attacatcgc ccccatcaga taaacaacag tgaacacaca gatccaaacc
    48121 acatccagga agtgccagaa caggctcagg cacatgatgc gggtacggtt agtgctggtc
    48181 aggccgcgac gggcgatttg caccatcagc accgccatcc agataagacc ggaagtgacg
    48241 tgcagaccgt gcgtgccgac cagcgcaaag aacgctgaca ggaagccgct gcgatccgga
    48301 cccatgccgt taacaatcag gtgatggaat tcatagattt ccatcccgat aaatccggca
    48361 ccaaacaacc aggtcaacgc cagccaggag ataacctggc ttttgttgtt tttgtacatg
    48421 gcgatagccg ccatgccgta ggtgatggag ctgaacaaca gcaagaaagt ttcaaccaga
    48481 acaaacggca gttcgaaaat gtccttacct gtcgggccgc ctgcggtgcc gttcaccaga
    48541 acggcatagg tagcaaacaa gatagagaac agaatgcagt cgctcatcag gtagatccaa
    48601 aatccgaaga ttttggttcc gcctgcatcg tggtgcccgt gttcgtgcgc gtgggcagtc
    48661 gcgtgcgtca aagtatcagt tgccattttt cagccctgcc ttagtaatct catcgaaatg
    48721 ctggttttcc agtttttcga tttctgccac cggcacgtag taatccacgt cctcgtcgaa
    48781 gcttttcacg atccaggtga tgatcatgcc tgcgaagcca acaatcgcca gccaccagat
    48841 atgccagatc atggcgaaac cgaagatggt ggagaaagcc gcaatgacga taccggcacc
    48901 gctgtttttc ggcatatgaa tttcttcata gtggtcaggc tttttgtacg cttcgccttt
    48961 ctctttcatt tcccagaatg catcacgctc gtgaacgtgc ggcacaacgg caaagttata
    49021 gaacggaggc ggggaagagg ttgcccactc cagcgtacgg ccaccccacg ggtcgccagt
    49081 caggtcacgg ttctggtcgc ggtcacgaat tgaaacgtac atctgaataa cgaggcagag
    49141 aatacccagc gcaatcagta ccgcaccgct ggctgcaatc atcagcatgg tgtggaactg
    49201 cgggtcaatc tgctggctca aacgacgggt catgcccatg aagcccagcg catacagtgg
    49261 cataaaggca acgaagaagc cgatgatcca gaaccagaac gcgcgtttac cccaggtttc
    49321 gttcagtttg aaaccgaacg ctttaggcca ccagtaggtc atccctgcga agcagccgaa
    49381 gaccacgccg ccgatgatca cgttatggaa gtgcgcaatc aggaacaggc tgttatgcag
    49441 aacgaagtcc gcgcccggta ctgccagcag cacgccagtc atcccgccca ccgagaaggt
    49501 gacgataaaa ccgatggtcc acagcatcgc agaatggaac acgatgcggc cctgatacat
    49561 ggtgaacagc cagttgaaga tcttcacccc ggtcgggatg gcgataatca tcgtggtgat
    49621 accaaagaag gcgtttacgt tcgcgcccgc acccatcgta aagaagtggt gcagccagac
    49681 gatgaacgac agcacggtga tacagacggt tgcccatacc agcgaggtat aaccaaacag
    49741 acgtttacgc gagaaggttg ccgcaatttc ggagaacaca ccgaaaacag gcaggatcag
    49801 gatgtaaact tccgggtggc cccaggccca aatcaggttg atgtacatca tcatgttgcc
    49861 acccatatcg ttggtaaaga aatgggtgcc cagatagcga tccagggtca acaacgcgac
    49921 ggtaaccgtc agaattggga aggaagcaat aatcagtacg tttgcgcaca gtgatgccca
    49981 ggtaaatact ggcatcttga acatggtcat gcccggtgcg cgcatcttca gaatggtaac
    50041 gaagaagttg ataccggtaa gcgtcgtacc tataccggat agctggagac tccatatcca
    50101 gtaatcgaca ccgactcccg gactgtactc tattcccgat agcggtggat aggccagcca
    50161 gccggtctgc gcaaattcgc ccacgccgag agaaacgtta accagaatca caccaacaac
    50221 ggtaaaccag aagcttaagt tgttgaggaa cgggaacgca acgtcacgcg cgccgatctg
    50281 cagcggaacc accaggttca tcagaccgat aacgaaaggc atcgccacga agaagatcat
    50341 aatcacgccg tgcgcggtga agatctgatc gtagtggtga ggaggcagga agcccgcttc
    50401 gcccgccgag gcaagggcct gctggctacg catcataatg gcgtcagcaa aaccacgcag
    50461 caacatcaca atcgccacga tgatatacat gatacctagg cgtttatggt cgacggaggt
    50521 cagccactct ttccacaggt aggtccactt accgaagtaa gtgatcaggc caacgagcgc
    50581 cagacctccc aaaataatgc cagcgatcgt aaccatgacg ataggttcat ggaacgggac
    50641 tgcatcaagt gataattttc cgaacatctt tattcttcct caaccccttt aatgggcgga
    50701 ttccgcgtgg ctcatgtcca tgccttccat accttcgtgt gcactgtgct caccttctgg
    50761 ctgggtcatg tccatgctct taccgtgagc cataaacttg ttaatcacat cagcaaacaa
    50821 gtctggtttc acgttggaga aatattccac ctggttgtat tcgctaggcg cggccagttt
    50881 ttcgaacgct gccatgtcag acatggtgtt cggcgactgt ttcgcttttg cgacccattg
    50941 gtcgaatgcg gcgcgatccg gtgttgcaat agctttgaac ttcatgcctg agaagcccgg
    51001 gccgctgtag ctggcggaga taccgtcata agtaccgggt tcgttggcga tcagatgcag
    51061 gcgagtctgc ataccggcca tggcataaat ctggctaccc agacgcggaa tgaagaagga
    51121 gttcatcacg gagttggagg tcactttgaa gtacaccgga gtgttcgccg ggaaagcgat
    51181 ttcattcacg gtagcaatgc cctgttccgg gtagatgaag aaccatttcc agtccatgga
    51241 aaccacttcg atggtaatgg gcttctcgtc gtgtgccagc ggcttgctag gctcaagagc
    51301 gtgagtggtt ttccaggtca gtaccgcaag gaagatgatg attaagatag gtaccgtcca
    51361 gaccacagct tccactttat tggagtgtga ccagttcggg ctgtacttag catctttatt
    51421 gctcgcacgg tacttccagg cgaaaccaac agccatcaag attgcgggaa taacgacaat
    51481 caacatcagg ccaaatgccg tcagtatcag tgaacgttgc tccagaccaa tctgtccttt
    51541 gggatctaac agcgcagaat tacagccact gagcaataca gtgcctgcaa ataatgacaa
    51601 ccatcccaaa cttttattgt atttcctgag tctcatttaa cgacctcaat tccacgggat
    51661 ctggtggcgt ttaaagtgtg tgggcatttt acgggaaggt tacattactg taaacatgat
    51721 taaattcctg ttacttggat ttggcttcca ggtcacatat gttgcaaaac atatcggatt
    51781 gattttaaga agctgttgca aaagggcgtt ataacaaaag gggagtgcag aaggagtctg
    51841 ggcgggcaat tggtataacc aatgcgaaat aaaacaatta tttaacaaat aattatcatt
    51901 aaggtgacaa cttggtagtg agaaaataaa gactcattag ctgaatcgtg taagaaaaat
    51961 agaattcata aatggcgtca ataatttcca gacgctaagc cgcacaaaag aacaaatatt
    52021 aataagcgat gctgatgttt atttagccgt aataattacg gcgagtgatt actacagcta
    52081 aataatattt acagattacg tcagatgcgt ttttcgtagc gccagataat ccagtaaacc
    52141 accaagcacg acgccagaaa gggcgactaa aaccccgact tccagcagag caggcaggaa
    52201 agagaagtgc gtcaaatcca gcgcgtccat cgtcaacagc agtaaccaca cggccaacag
    52261 gctgacgccc gccgccagtg tccacatggc aaaggcataa cctgccggat attcggtacg
    52321 ggagataaag ttgtcattta ctcgtgtata ttcaagcgtc tggcgacaaa tcagcagtaa
    52381 aataagccct ggtacggcag cggcgacgga gaacagatag aatgtcgacc agccgtgtgc
    52441 ttcaacaaac caacccgcca cggggccgac ataaactcgc cctacagcag aaagcgctga
    52501 gagcagggca aattgagtag cggaaaatga cttattacac agcgtcatta acagcgcgac
    52561 aaaggctgat gtacccatcc cgccacagag gttttcgaaa aagacggctg cacccatgct
    52621 gtagagatgc ttatcagtaa tcgacagcag ccagtaaccg gcgttagatg caccttgtaa
    52681 aatgccgaaa atcagcagtg cacggaacag cgacaggcgc tgcatcaaaa tcccaccgta
    52741 caatgcgcca acaatggtcg ccagtaagcc aagcgttttg ttaaccacgc ctacttcacc
    52801 cgcatcaaac ccgacgccgc gaatcaaaaa cgtggttgtc aggctcatag cgaatgcgtc
    52861 gcccagctta tacagcacga taagaagcaa aataagccag gcattattgc gaccaaagaa
    52921 atcgcgcaga ggtgcaacaa ccgcttgttc cagcgttttg ggcacaggaa tggtgtcggt
    52981 gggttctggt gcaagcaacg tcgcgataat acaggggatc aacagcgccg ccatcaacca
    53041 gtacatgccc tgccagccca gccatttatc tgccagccac agggctaagc cgccggaaac
    53101 cagcatccct aaacggtaac ccagcacgct gattgccgcg cccgcaccac gttcttctgc
    53161 cgggagcaca tcggttttcc atgcatcgaa gacaatatcc tgggaggcag agcaaaaagc
    53221 gatcaccacc gccagtgccg ccatccagcg gagctgggtg cctggttcga gaaaacccat
    53281 cgccgcaatg gcgactaata acagaatttg cgtggcgagc agccaaccgc gccgccgccc
    53341 gaaaaatggg ggcgtgtagc ggtccatcag tggtgaccag aggaatttaa aaacgtaagc
    53401 ctggcctacc agagagaaga aaccaatggt tttaagatcg atattctcga ccgtcatcca
    53461 ggcctgtaag gtgccggacg tcagggcgag cggtagcccg gaagcaaaac ccagaatcag
    53521 caatatggct gaacgtggct gttgaaaaat acgtaaatat tgactggaca tgggcgtcta
    53581 caggcccggc ttgcaccggg ccagagggca gaaattaacg cgcgttctgc ttgatgaatt
    53641 cgtggatgct ggtgtcctga gacatatcag cgatggtatc ggtcagcaca ctgttaaccg
    53701 catcggcgat atttttgttg gaggcctgga acgcaccttc aacgttgtag ctggcacgat
    53761 agtttttggt cattttgttg ccattctgcg cggtagcgat gatagcgata tccgctttgg
    53821 tggcgatgtt atagcgcacg ttgccctggg acacgtcagc atacagttgg ctaacgatga
    53881 tttgcagatt aaccgggcca ttcggaccaa ccatgtaacc acgcgcggtc atctgttttt
    53941 ccagcacttc ttgcagcagg aaacgcagat cgcgggaggc ggtcagggta acgatttgat
    54001 tatcgcgggt gacttttgcc agcgcctgat cggtacgctg atcggcacca ttaatgctta
    54061 cggtgacgcc catcaggctt ggatcctgct gtggcagtgt tatcgtcggt gaaacttcaa
    54121 tagttgttgg cggttttgcg catcctgcaa gcataaacag agcaactaac gggaagagga
    54181 tttttttgaa catgttcggg ctctcagaga ctcttaagcg tgtttggtaa aaattcccgc
    54241 catcataaca ttgccaacgg cgaggggaag tgggtaaggc atgtaaattc atcatgttga
    54301 cgaaataatc gcccctggta aaagaaacgc tgatgcgagg cctgtgtttc aatctttaaa
    54361 tcagtaaact tcatacgctt gacggaaaaa ccaggacgaa acctaaatat ttgttgttaa
    54421 gctgcaatgg aaacggtaaa agcggctagt atttaaaggg atggatgaca tctcagcgtt
    54481 gtcggaggag atatttcatg atgatacgtg agcggataga agaaaaatta agggcggcgt
    54541 tccaacccgt attcctcgaa gtagtggatg aaagctatcg tcacaatgtc ccagccggct
    54601 ctgaaagcca ttttaaagtt gtgctggtca gcgatcgttt tacgggtgaa cgttttctga
    54661 atcgtcatcg aatgatttac agtactttag cggaggaact ctctactacc gttcatgcgc
    54721 tggctctgca tacttacact attaaggagt gggaagggtt gcaggatacc gtctttgcct
    54781 ctcctccctg tcgtggagca ggaagcatcg cgtaaaaacg catttgcaac tgtcggcgct
    54841 tttccagtat gttgctaaag attttatgaa aaacggcctg cgggccgttt tgttttgtct
    54901 ggattttgcg ctttttgccc agcattcaga cgaaaattgc ccgggaattg tgaaaaaata
    54961 cgcgacagcg cgcaataacc gttctcgact cataaaagtg atgccgctat aatgccgcgt
    55021 cctatttgaa tgctttcggg atgattctgg taacagggaa tgtgattgat tataagaaca
    55081 tcccggttcc gcgaagccaa caacctgtgc ttgcggggta agagttgacc gagcactgtg
    55141 attttttgag gtaacaagat gcaagtttca gttgaaacca ctcaaggcct tggccgccgt
    55201 gtaacgatta ctatcgctgc tgacagcatc gagaccgctg ttaaaagcga gctggtcaac
    55261 gttgcgaaaa aagtacgtat tgacggcttc cgcaaaggca aagtgccaat gaatatcgtt
    55321 gctcagcgtt atggtgcgtc tgtacgccag gacgttctgg gtgacctgat gagccgtaac
    55381 ttcattgacg ccatcattaa agaaaaaatc aatccggctg gcgcaccgac ttatgttccg
    55441 ggcgaataca agctgggtga agacttcacc tactctgtag agtttgaagt ttatccggaa
    55501 gttgaactgc agggtctgga agcgatcgaa gttgaaaaac cgatcgttga agtgaccgac
    55561 gctgacgttg acggcatgct ggatactctg cgtaaacagc aggcgacctg gaaagaaaaa
    55621 gacggcgctg ttgaagcaga agaccgcgta accatcgact tcaccggttc tgtagacggt
    55681 gaagagttcg aaggcggtaa agcgtctgat ttcgtactgg cgatgggcca gggtcgtatg
    55741 atcccaggct ttgaagacgg tatcaaaggc cacaaagctg gcgaagagtt caccatcgac
    55801 gtgaccttcc cggaagagta ccacgcagaa aacctgaaag gtaaagcagc gaaattcgct
    55861 atcaacctga agaaagttga agagcgtgaa ctgccggaac tgactgcaga attcatcaaa
    55921 cgtttcggcg ttgaagatgg ttccgtagaa ggtctgcgcg ctgaagtgcg taaaaacatg
    55981 gagcgcgagc tgaagagcgc catccgtaac cgcgttaagt ctcaggcgat cgaaggtctg
    56041 gtaaaagcta acgacatcga cgtaccggct gcgctgatcg acagcgaaat cgacgttctg
    56101 cgtcgccagg ctgcacagcg tttcggtggc aacgaaaaac aagctctgga actgccgcgt
    56161 gaactgttcg aagaacaggc taaacgtcgc gtagttgttg gcctgctgct gggcgaagtt
    56221 atccgcacca acgagctgaa agctgacgaa gagcgcgtga aaggcctgat cgaagagatg
    56281 gcttctgcgt acgaagatcc gaaagaagtt atcgagttct acagcaaaaa caaagaactg
    56341 atggacaaca tgcgcaatgt tgctctggaa gaacaggctg ttgaagctgt actggcgaaa
    56401 gcgaaagtga ctgaaaaaga aaccactttc aacgagctga tgaaccagca ggcgtaattt
    56461 acgcagcata acgcgctaaa ttcgcacaaa ggcccgtcac cgccaggtgg tgggcttttt
    56521 tttgtcatga attttgcatg gaaccgtgcg aaaagcctct ttcggtgtta gcgtaacaac
    56581 aaaagattgt tatgcttgaa atatggtgat gccgtaccca taacacaggg actagctgat
    56641 aatccgtcca taaggttaca atcggtacag caggtttttt caattttatc caggagacgg
    56701 aaatgtcata cagcggcgaa cgagataact ttgcacccca tatggcgctg gtgccgatgg
    56761 tcattgaaca gacctcacga ggtgagcgct cttttgatat ctattctcgt ctacttaagg
    56821 aacgcgtcat ttttctgact ggccaggttg aagaccacat ggctaacctg attgtggcgc
    56881 agatgctgtt cctggaagca gaaaacccag aaaaagatat ctatctgtac attaactctc
    56941 caggcggggt gattactgcc gggatgtcta tctatgacac catgcagttt atcaagcctg
    57001 atgtcagcac catctgtatg ggccaggcgg cctcgatggg cgctttcttg ctgactgcag
    57061 gggcaaaagg taaacgtttc tgcctgccga attcgcgcgt gatgattcac cagccgttgg
    57121 gcggctacca gggccaggcg accgatatcg aaattcatgc ccgtgaaatt ctgaaagtta
    57181 aagggcgcat gaatgaactt atggcgcttc atacgggtca atcattagaa cagattgaac
    57241 gtgataccga gcgcgatcgc ttcctttccg cccctgaagc ggtggaatac ggtctggtcg
    57301 attcgattct gacccatcgt aattgatgcc agaggcgcaa ctgtgccgct atacttatcc
    57361 agggcggcac aacgctgtaa gcggcttgcg cctgagaatg gcatttgcgt cgtcgtgtgc
    57421 ggcacaaaga acaaagaaga ggttttgacc catgacagat aaacgcaaag atggctcagg
    57481 caaattgctg tattgctctt tttgcggcaa aagccagcat gaagtgcgca agctgattgc
    57541 cggtccatcc gtgtatatct gcgacgaatg tgttgattta tgtaacgaca tcattcgcga
    57601 agagattaaa gaagttgcac cgcatcgtga acgcagtgcg ctaccaacgc cgcatgaaat
    57661 tcgcaaccac ctggacgatt acgttatcgg tcaggaacag gcgaaaaaag tgctggcggt
    57721 cgcggtatac aaccactaca aacgtctgcg caacggagat accagcaatg gcgtcgagtt
    57781 gggcaaaagt aacattctgc tgatcggtcc gaccggttcc ggtaaaacgc tgctggccga
    57841 aacgctggcg cgcctgctgg acgttccgtt caccatggct gacgcaacca cgctgaccga
    57901 agccggttat gtgggcgaag acgttgaaaa catcattcag aagctgttgc agaagtgcga
    57961 ttacgacgta cagaaagcgc agcgcgggat tgtctacatc gatgaaatcg acaagatttc
    58021 tcgtaagtca gacaacccgt ccattacccg agacgtttcc ggtgaaggcg tacagcaggc
    58081 actgttaaaa ctgatcgaag gtacggtagc tgctgttccg ccgcaaggtg ggcgtaaaca
    58141 tccgcaacag gaattcttgc aggttgatac ctctaagatc ctgtttatct gtggcggtgc
    58201 gtttgccggt ctggataaag tgatttccca tcgtgtagaa accggttccg gcattggttt
    58261 tggcgcgacg gtaaaagcga agtccgacaa agcaagcgaa ggtgaactgc tggcgcaggt
    58321 tgaaccggaa gatctgatca agtttggtct gatccctgag ttcattggtc gtctgccggt
    58381 tgtcgcaacg ttgaatgaac tgagcgaaga agctctgatt cagatcctca aagagccgaa
    58441 aaacgccctg accaagcagt atcaggcgct gtttaatctg gaaggcgtgg atctggaatt
    58501 ccgtgacgag gcgctggatg ctatcgctaa gaaagcgatg gcgcgtaaaa ccggtgcccg
    58561 tggcctgcgt tccatcgtag aagccgcact gctcgatacc atgtacgatc tgccgtccat
    58621 ggaagacgtc gaaaaagtgg ttatcgacga atcggtaatt gatggtcaaa gcaagccgtt
    58681 gctgatttat ggcaagccgg aagcgcaaca ggcatctggt gaataattaa ccattcccat
    58741 acaattagtt aaccaaaaag gggggatttt atctcccctt taatttttcc tctattctcg
    58801 gcgttgaatg tgggggaaac atccccatat actgacgtac atgttaatag atggcgtgaa
    58861 gcacagtcgt gtcatctgat tacctggcgg aaattaaact aagagagagc tctatgaatc
    58921 ctgagcgttc tgaacgcatt gaaatccccg tattgccgct gcgcgatgtg gtggtttatc
    58981 cgcacatggt catcccctta tttgtcgggc gggaaaaatc tatccgttgt ctggaagcgg
    59041 cgatggacca tgataaaaaa attatgctgg tcgcgcagaa agaagcttca acggatgagc
    59101 cgggtgtaaa cgatcttttc accgtcggga ccgtggcctc tatattgcag atgctgaaac
    59161 tgcctgacgg caccgtcaaa gtgctggtcg aggggttaca gcgcgcgcgt atttctgcgc
    59221 tctctgacaa tggcgaacac ttttctgcga aggcggagta tctggagtcg ccgaccattg
    59281 atgagcggga acaggaagtg ctggtgcgta ctgcaatcag ccagttcgaa ggctacatca
    59341 agctgaacaa aaaaattcca ccagaagtgc tgacgtcgct gaatagcatc gacgatccgg
    59401 cgcgtctggc ggataccatt gctgcacata tgccgctgaa actggctgac aaacagtccg
    59461 ttctggagat gtccgacgtt aacgaacgtc tggaatatct gatggcaatg atggaatcgg
    59521 aaatcgatct gctgcaggtt gagaaacgca ttcgcaaccg tgttaaaaag cagatggaga
    59581 aatcccagcg tgagtactat ctgaacgagc aaatgaaagc tattcagaaa gaactcggtg
    59641 aaatggacga cgcgccggac gaaaacgaag ccctgaagcg caaaatcgac gcggcgaaaa
    59701 tgccgaaaga ggcaaaagag aaagcggaag cagagttgca gaagctgaaa atgatgtctc
    59761 cgatgtcggc agaagcgacc gtagtgcgtg gttatatcga ctggatggta caggtaccgt
    59821 ggaatgcgcg tagcaaggtc aaaaaagacc tgcgtcaggc gcaggaaatc cttgataccg
    59881 accattatgg tctggagcgc gtgaaagatc gcatccttga gtatcttgcg gttcaaagcc
    59941 gtgtcaacaa aatcaaggga ccgatcctct gcctggtagg gccaccgggg gtaggtaaaa
    60001 cgtccctggg gcagtccatc gccaaagcca ccgggcgtaa atatgtccgt atggcgctgg
    60061 gcggcgtgcg tgatgaagcg gaaatccgtg gtcaccgccg tacttacatc ggttctatgc
    60121 cgggtaaact gatccagaaa atggcgaaag tgggcgtgaa aaacccgctg ttcctgctcg
    60181 atgagatcga caaaatgtct tctgacatgc gaggcgatcc ggcttccgca ctgcttgaag
    60241 tgctggatcc agagcagaac gtagcgttca gcgaccacta cctggaagtg gattacgacc
    60301 ttagcgacgt gatgtttgtc gcgacgtcga actccatgaa cattccggca ccgctgctgg
    60361 atcgtatgga agtgattcgc ctctccggtt ataccgaaga tgaaaaactg aacatcgcca
    60421 aacgtcacct gctgccgaag cagattgaac gtaatgcact gaaaaaaggt gagctgaccg
    60481 tcgacgatag cgccattatc ggcattattc gttactacac ccgtgaggcg ggcgtgcgtg
    60541 gtctggagcg tgaaatctcc aaactgtgtc gcaaagcggt taagcagtta ctgctcgata
    60601 agtcattaaa acatatcgaa attaacggcg ataacctgca tgactatctc ggtgttcagc
    60661 gtttcgacta tggtcgcgcg gataacgaaa accgtgtcgg tcaggtaact ggtctggcgt
    60721 ggacggaagt gggcggtgac ttgctgacca ttgaaaccgc gtgcgttccg ggtaaaggca
    60781 aactgaccta taccggatcg cttggcgaag tgatgcagga gtccattcag gcggcgttaa
    60841 cggtggttcg tgcgcgtgcg gaaaaactgg ggatcaaccc tgatttttat gaaaaacgcg
    60901 acatccacgt ccacgtaccg gaaggtgcga cgccgaaaga tggtccgagt gccggtattg
    60961 ctatgtgcac cgcgctggtt tcttgcctga ccggtaaccc ggttcgtgcc gatgtggcaa
    61021 tgaccggtga gatcactctg cgtggtcagg tactgcctat cggtggtttg aaagaaaaac
    61081 tactggcagc gcatcgcggc gggattaaaa cagtgttaat tccgttcgaa aataaacgcg
    61141 atctggaaga gattcctgac aacgtaattg ccgatctgga tattcatcct gtgaaacgca
    61201 ttgaggaagt tctgactctg gcgctgcaaa atgaaccgtc tggcatgcag gttgtgactg
    61261 caaaatagtg acctcgcgca aaatgcacta ataaaaacag ggctggcagg ctaattcgga
    61321 cttgccagcc tttttttgtc tcgctaagtt agatggcgga ttgggcttgc ccttattaag
    61381 gggtgttgta aggggatggc tggcctgata taactgctgc gcgttcgtac cttgaaggat
    61441 tcaagtgcga tataaattat aaagaggaag agaagagtga ataaatctca attgatcgac
    61501 aagattgctg caggggctga tatctctaaa gctgcggctg gccgtgcgtt agatgctatt
    61561 attgcttccg taactgaatc tctgaaagaa ggggatgatg tagcactggt aggttttggt
    61621 acttttgccg ttaaagagcg tgctgcccgt actggccgca acccgcagac cggtaaagag
    61681 atcaccatcg ctgccgctaa agtaccgagc ttccgtgcag gtaaagcact gaaagacgcg
    61741 gtaaactaag cgttgtcccc agtggggatg tgacgaagtt caagggcgca tctactgatg
    61801 tgcctttttt atttgtaatc ggtgactttc tgcgtcttgt gggctgacaa ttgcccccgt
    61861 ttcttgtcac aataggcctt tgcgcgcatc gatacgttgc gtgaggtaca cagtcatcta
    61921 cagcggagtg ttgttacacc atgatggaca gcttacgcac ggctgcaaac agtctcgtgc
    61981 tcaagattat tttcggtatc attatcgtgt cgttcatatt gaccggcgtg agtggttacc
    62041 tgattggcgg aggcaataac tacgccgcaa aagtgaatga ccaggaaatc agccgtgggc
    62101 agttcgagaa tgccttcaac agcgagcgta atcgcatgca gcaacagctg ggcgatcaat
    62161 actctgagct tgcagcgaac gaaggctata tgaaaaccct gcgtcaacag gtgctgaatc
    62221 gtctgatcga cgaggcgctt ctggatcagt acgctcgtga gctgaaactg ggtatcagcg
    62281 atgagcaggt taaacaggcg attttcgcga ccccagcctt ccaggttgac ggcaaatttg
    62341 ataacagccg ctataacggt atcctcaacc agatggggat gaccgccgat cagtacgccc
    62401 aggcgctgcg taaccagctc actacccaac agctgattaa cggcgttgcc ggtaccgatt
    62461 ttatgctgaa aggtgaaacc gacgagctgg cggcactggt agctcaacaa cgcgtggtgc
    62521 gtgaagcgac tatcgatgtt aacgcgctgg cggcgaagca gcctgtgacc gaacaggaaa
    62581 ttgccagcta ctacgaacaa aacaaaaaca atttcatgac gccggaacaa ttccgcgtga
    62641 gttacatcaa gctggatgcc gcaacgatgc agcaaccggt tagcgatgcg gatatccaga
    62701 gctactacga tcagcatcag gatcaattca cccagccgca gcgtacccgc tacagcatca
    62761 tccagaccaa aactgaagat gaagcgaaag cggtacttga tgagctgaat aaaggcggtg
    62821 attttgctgc gttagccaaa gaaaaatctg ccgatattat ctctgcccgt aacggcggcg
    62881 atatgggttg gttagaagat gccactatcc cggacgaact gaaaaatgct ggtctgaaag
    62941 aaaaaggcca actctctggt gtcatcaaat cttcggtcgg tttcctgatt gtacgtctgg
    63001 acgacattca gccagcgaaa gtgaagtcgt tagacgaagt gcgtgacgat gtcgcggcga
    63061 aagtgaaaca cgaaaaagcc ctcgatgcgt actacgcact gcagcagaaa gtgagcgatg
    63121 cagcaagcaa tgataccgag tctctggccg gtgcagagca agctgccggc gttaaagcca
    63181 ctcagacggg ttggttcagc aaagataacc tgccggaaga gttgaacttc aagccagttg
    63241 ccgacgctat cttcaacggc ggtctggtag gtgaaaacgg cgcgccgggc atcaactctg
    63301 acatcatcac cgtagacggc gaccgcgcat tcgtgctgcg catcagcgag cacaaaccgg
    63361 aagcggtgaa accgttggca gatgttcagg aacaagttaa ggcactggtt cagcacaaca
    63421 aagctgaaca acaggcgaaa gtggatgctg agaaactgct ggttgatttg aaagccggca
    63481 aaggtgcgga agctatgcag gctgccggtc tgaaatttgg cgagccgaaa accttaagcc
    63541 gttccggtcg tgacccgatt agccaggcgg cgtttgcact gccactgcca gcgaaagaca
    63601 aaccgagcta cggtatggcg accgatatgc aaggtaatgt ggttctgctg gcgctggatg
    63661 aagtgaaaca aggttcaatg ccggaagatc agaaaaaagc gatggtgcag ggtatcaccc
    63721 agaacaacgc acaaatcgtc tttgaagctc tgatgagtaa cctgcgtaaa gaggcgaaaa
    63781 tcaaaattgg cgatgcgctg gaacagcaat aatcctgaag ccgcctcgca aaaaaatgct
    63841 ttgcagctgt aacaagaaaa ggtcgctttc gcggcctttt ccatttctga acattgccat
    63901 ttgtttactg ttttcactgc cgttaaggtg attccactgt taacaaacaa ggagaaaaca
    63961 gtatgaaaca cggaattaaa gcactgctca ttaccctgtc tctggcttgt gccggaatgt
    64021 ctcatagcgc gctggcggca gctcctgcgg cgaaaccgac aacggtagaa accaaagcgg
    64081 aagctcctgc agcacaaagt aaagcagcag ttccggcgaa agccagtgac gaagaaggca
    64141 cccgggtcag cattaataat gccagcgcgg aagagttagc ccgcgcgatg aatggcgttg
    64201 gcctgaagaa agcgcaggcg attgtcagtt atcgcgaaga gtacggtccg tttaaaacgg
    64261 tggaggatct aaagcaggtg ccggggatgg gcaattcgct ggtggagcgt aatctggcag
    64321 tattaaccct gtaattaatt tgcatagtgg caattttttg ccagactgaa gaggtcatac
    64381 cagttatgac ctctgtactt ataacagttc ttataacaac aacgtaaggt tattgcgcta
    64441 tgcaaacaca aatcaaagtt cgtggatatc atctcgacgt ttaccagcac gtaaacaacg
    64501 cccgctacct tgaatttctc gaagaagccc gctgggatgg gttggaaaat agcgacagtt
    64561 ttcagtggat gacggcccat aacatcgcct tcgtcgtggt caatatcaat attaactatc
    64621 gtcgcccggc ggtattaagc gacctgttaa ctattaccag tcagttgcag caattaaacg
    64681 gtaaaagtgg catcttaagc caggtcatta cactggagcc ggaagggcag gtagtagcgg
    64741 atgcgcttat tacgtttgtt tgtattgatc ttaaaacgca gaaagcatta gctctggaag
    64801 gggaattgcg cgaaaagctg gagcagatgg ttaagtaaac gttttgtggt gccggatgct
    64861 caagccgcat ccggcgacac ccggaataat taattcaacc cggttttctg cttcatcgct
    64921 gccatcaccg tcggtttatc ggccagataa tgattcaaac cgttggcgcg taaattacat
    64981 gccgcacaat gaccgcaacc gtcgccttta atgccgttat agcaggtcag cgtttcgtta
    65041 cggactaaat ccagcttgcc gtaataatct gccagcgccc aggtttccgc tttatcaatc
    65101 cacatcagcg gcgtttcaaa acgaatatct ttcgccatgc ctaaactgac ggcatggttt
    65161 agtgctttca caaactcatc gcggcaatcc gggtagccgg agaaatccgt ttcgcagacg
    65221 ccggtaatta cggcttctgc ttttacctga tacgcatata ttgccgccag cgtcaggaac
    65281 aaaatattac gcccagggac aaacgtattc gggatgccat cggcttcagg ttcataatca
    65341 ggcaccggaa tgctgtcacg cgtcaggctg ctgaccgcca gctcgttgag cagcgttaca
    65401 tcaagaacct tatgcgcgcg tgctcccagt ttcagcgcca gttcgcgtgc cacgtcgatt
    65461 tctgcgcgat gtcgctgacc gtaatcgaac gtcacgcaat ggacttcatc atattgttgt
    65521 aatgcctgca ccagacaggt ggtggaatcc tggcctccac tgaacacaac gacagcacgt
    65581 ttcatagata atcctgcttg aacaataaaa gcgttatggt aacgcctgcg atgaacccgg
    65641 accagctatt cattgcgacg gcgcgggaag ccaggcttcg gtaaattcaa accagccgcg
    65701 cggtgtcagt cgcacaccgt tcacgccggg aggggcgcta atgcgatagt gatagttgaa
    65761 cagcggcgtc agcgtcgcat ctgccattaa ctggctaaaa accgctttca gggcattaaa
    65821 tcggttttcc tcatcaggca ttacttgcac cgcgtccagt gtcgattgca aatgtgcata
    65881 tgctggagcg tcgaaaacat gtggccacag tggatcgcaa cgcagccatt gctccagggt
    65941 atattccggt gcttcgccaa ttaatctgtc gcccatcatg aggtctgcgt gtgccagtag
    66001 ggtcgtgtcg tcccagtttt ttgcgttatg aaaaataatt gtaagttcac agccttccgc
    66061 tgccagtgtc gcctgtagac gttctgccat ggtatgaagt tctatcggta ggtgataaac
    66121 cagcgtcaag gttttcggta gtttgacctc atccggtact tgccattgcg gaatagtcca
    66181 gcctggcagt aatgcatgac tggcggtgat caggttttct ccgacttcta acgtttgtaa
    66241 taaaccggat tgatgaataa tggagatcac ttttcgcgcc tgccagaggg acagtcgggg
    66301 acttttgcgc aacgttaaat agcaaaaacc taaactgatg ccactactga cctggctgac
    66361 ccgttgcagc tcctccggtt tgccgatggt gatttgcacg ggatgccgac aactggttcc
    66421 caaatctttt tcgaaaagcg gcggagttat ccagtactca accgctttaa gcagcggatg
    66481 acgtaaatgg taataatcat ggctttccag gcgcaccagc tccgctgtga attgtgttaa
    66541 gcgaaaagga cccgtgccga tcagtgggaa ttgcggatgc gccagatggc tgcaatagct
    66601 cgccagccgg tgcgcaagcc agtaatcagg gcgatgtaaa aagaaggtca gacactgcgg
    66661 atgggtgact tcaatacgct tcacgctaat aaataattga tccactgctg gcagttgtaa
    66721 cagcatcaat aatcgctggt gtaagtgtga ggcttttact gcatcgccgt tatgccagtg
    66781 tagggttgaa cgaagataaa agtcccagcg taacccgtca gtagaggttt cccagtgatg
    66841 cgctaaatcg ccaatcgggc gctgggtatt attatcgaag cgggtcaggc cggaaaatat
    66901 ctgcccggcc agatgctgct cggcacggcc gggcaaaaag cccggttgta gcggttcgag
    66961 cgggcgatag tagggaatac gcaacgtggg cgtatcgttt tgccattgtc cgcccataaa
    67021 cggctgtaac agagtgcgca gctcacctgg ggccagttgc gccagctcca gcacatcttg
    67081 ctgctttccg gtttccagcg cctgttccat catcgcattg cgtagcgatt ctggcgtgac
    67141 cagaaagcgt aattgtccgc gctttccgcg tcctgactgc gcctgccact ccagccatcc
    67201 cgcctcctgt gcctggcgta acagcgtacg aacatggcgt tcgctgcaaa aacagcgttc
    67261 ggccagttcg ctgactgtga cggtttgcgg ctttccggcg gaaggttgcc acagacgttg
    67321 atactggtta agacggttga gcagtcgcat ataaacccgg aacaatatta tttaactatt
    67381 cactattact tccgtatata tcaggtgata ctcaatcact attaaccgtg tcacagagtg
    67441 gagaaagaaa tggctcgtct ggcagcattt gatatggatg gcactttatt gatgcctgac
    67501 catcatttag gtgagaaaac cctctctact ttggcgcggc tgcgtgaacg cgacattacc
    67561 ctcacttttg ccacggggcg tcatgcgctg gagatgcagc atattctcgg ggcgctatcg
    67621 ctggatgcat atttgattac cggcaacgga acgcgcgtgc attctctgga aggtgaactt
    67681 ttacatcgtg atgatttacc tgcggatgtc gcggagctgg tgctgtatca gcaatgggat
    67741 acccgagcca gcatgcatat cttcaatgac gatggttggt ttaccgggaa agagatccct
    67801 gcgttgttgc aggcatttgt ctatagcggt tttcgttatc agataatcga tgtcaaaaaa
    67861 atgccactcg gcagcgtcac caagatctgc ttctgtggcg atcacgacga tcttacacgc
    67921 ttgcagatcc agctatacga agcattaggc gagcgtgcac atttatgttt ttccgccacg
    67981 gattgcctcg aagtgctgcc ggtgggctgc aataaaggcg ctgcattgac ggtgctgacc
    68041 caacatttag gtttatcgtt acgcgattgc atggcctttg gtgatgcgat gaacgatcgc
    68101 gaaatgttag gcagtgtcgg tagcggattt attatgggca atgcgatgcc gcaactgcgc
    68161 gcggagctcc cgcatttacc ggtgattgga cattgccgaa atcaggctgt ctctcactat
    68221 ttgacgcact ggctggacta tccacatcta ccttattccc ccgaataacg agatcccttc
    68281 cagcaccggg caattgcccg gttttttttg cgttgaattt gtcattttgt gccgtggtgc
    68341 ttaaaccgca cagaataaat tgtcgcgatt tcacctttaa aatagaatta aaagagaaaa
    68401 aaattctctg tggaagggct atgttagata aaattgaccg taagctgctg gccttgctac
    68461 agcaggattg caccctctct ttgcaggcac tggctgaagc cgttaatctg acaaccaccc
    68521 cctgctggaa gcgtctgaaa cggctggagg acgacggtat ccttatcggc aaagtcgccc
    68581 tgctggatcc ggaaaaaata ggcctcggcc tgaccgcctt tgtgctgata aaaacgcaac
    68641 atcacagcag cgaatggtat tgccgctttg tcacggtggt taccgaaatg ccagaagtgc
    68701 tggggttctg gcgcatggcc ggtgaatacg attatctgat gcgcgtccag gttgccgaca
    68761 tgaaacgcta cgacgagttt tataagcgtc tggtaaacag cgtgccgggg ctgtcggacg
    68821 tcacttccag cttcgcgatg gaacagatta aatacaccac ttctttaccc atcgaataaa
    68881 tatccagaat caggtcagga cacaacgcgt gcgattattt gctcaattaa gctggtattt
    68941 ccgtcgggaa tggcgtcgct atctcggggc tgtcgccttg cttgtcatta tcgcgatgct
    69001 gcaactggtt ccgccaaaag tggttggtat tgttgtcgat ggcgtgacag aacaacactt
    69061 tactaccggg cagatcctga tgtggatcgc caccatggtg ctgattgccg ttgtggttta
    69121 tctcctgcgt tacgtctggc gcgtattgct gtttggtgcg tcttatcaac tggctgttga
    69181 actgcgtgaa gattattacc gccagctaag ccggcagcat cctgagtttt acctgcgtca
    69241 tcgcacgggt gacctcatgg ctcgtgcgac caatgacgtc gatcgcgtcg tgtttgccgc
    69301 cggagaaggg gtgctgacgc tggtggattc actggtaatg ggctgcgctg tgttgattat
    69361 gatgtctacg caaattagct ggcagttgac cttatttgcc ctgttgccga tgccagtgat
    69421 ggcgatcatg atcaagcgca acggcgatgc cttgcatgaa cgctttaagc tggcacaggc
    69481 ggcgttttcc agtcttaatg accgcaccca ggaaagcctc accagtatcc gcatgatcaa
    69541 agcttttggt ctggaagatc gtcagtcggc gttatttgcc gcggatgccg aagataccgg
    69601 caaaaaaaac atgcgggtgg cgcgtattga tgctcgtttc gacccgacca tctatatcgc
    69661 gattggtatg gcgaacttgc tggcgattgg cggcggtagt tggatggtgg tacagggcag
    69721 tttaacgctg ggccagctca ccagttttat gatgtattta ggtctgatga tttggccaat
    69781 gctggcgctg gcatggatgt ttaacattgt ggaacgtggc agcgcggcgt atagccgaat
    69841 tcgtaccatg ctggccgaag cgccagtcgt tattgatggt agtgataagg tgccagaagg
    69901 tcgtggtgaa ctggatgtga atattcgcca gtttacgtat ccgcagactg accatcctgc
    69961 gctggaaaac gtcaatttcg ccctgaaacc cggtcagatg gtaggtattt gcgggccgac
    70021 tggttccggc aaaagtaccc tgttgtcgct cattcagcgt catttcgacg tcagcgaggg
    70081 ggatatccgc tttcatgata ttcctctgac gaagttacaa ctcgatagct ggcgtagccg
    70141 cctggcggta gttagccaga caccgttcct tttttccgac accgtagcga acaacatcgc
    70201 gttgggttgc ccgaatgcca cccagcaaga gattgagcat gtcgcgcggt tagccagcgt
    70261 gcatgacgat attttgcgtt taccgcaagg ttacgataca gaagtgggcg agcgcggcgt
    70321 gatgctttcc ggtgggcaaa aacagcgtat ctccattgct cgtgcgttat tagtcaacgc
    70381 ggaaatcctc atccttgatg atgcgctttc ggcagtagac ggacgcacag agcaccagat
    70441 cctgcataac ctgcgccagt gggggcaggg aaggacggta atcatcagtg cccatcgcct
    70501 ttcggcactg acggaagcca gtgaaattat tgtgatgcag cacggacata tcgcccagcg
    70561 tggcaatcat gatgtgctgg cacaacaaag cggctggtat cgcgatatgt atcgctatca
    70621 acaactggag gcggcgctcg acgacgctcc ggaaaatcgc gaggaggccg tcgatgcgta
    70681 gttttagcca actgtggccg actctcaagc gtctgttagc gtacggttcg ccgtggcgta
    70741 aaccgttggg gattgcggtc ctgatgatgt gggttgcggc tgcggcagaa gtcagtgggc
    70801 cgctgcttat cagctatttt atcgacaata tggtagcgaa aaataacctg ccgttgaaag
    70861 tggttgcagg gctggctgcg gcgtatgttg ggctgcaact gtttgccgcc gggctacatt
    70921 acgcgcagtc gctgctgttt aatcgggcgg cagtaggcgt agtgcaacag ttgcgtaccg
    70981 acgtgatgga tgctgcgtta cgccagccat taagcgagtt tgatacccaa cccgtcgggc
    71041 aggtgatttc ccgcgtcacc aatgacactg aagtgatccg cgatctctac gttaccgtgg
    71101 tggcaactgt cctgcgtagc gccgcactgg tgggcgcgat gctggtggcg atgttcagcc
    71161 tcgactggcg aatggcgctg gtggcgataa tgattttccc ggtggtgctg gtggtaatgg
    71221 tgatatacca gcgttacagc acgccgattg tccgtcgtgt gcgcgcctat ctggcggata
    71281 tcaacgacgg ctttaacgaa atcatcaatg gcatgagcgt tatccagcag ttccgtcagc
    71341 aggcgcgatt tggcgaacgt atgggtgagg ccagtcgttc acactatatg gcgaggatgc
    71401 aaaccctgcg cctcgacggt tttctgctgc gtccgctgct gagtctgttt tcatcgctca
    71461 ttctttgtgg attgttgatg ctgtttggct tctctgtcag cggcaccatt gaagtgggcg
    71521 tactgtatgc gtttatcagc tatcttgggc ggcttaacga acccttaatc gaactgacca
    71581 cgcaacaggc gatgctgcaa caggctgttg ttgctggtga gcgcgtgttt gagctgatgg
    71641 acggaccgcg ccagcaatat ggcaatgatg atcgcccgtt gcagagcggc accattgaag
    71701 tcgataacgt gtcatttgct tatcgcgatg acaatatggt gctaaagaac attaatctct
    71761 cggtgccttc gcgcaacttt gtggcgctgg tcgggcatac cggcagtggt aaaagtaccc
    71821 tcgctagttt attgatgggc tattacccgc taacggaagg tgagattcgc cttgatggtc
    71881 gtccattaag ttcgctaagt cacagcgcgc tgcgccaggg cgtggcaatg gtgcagcaag
    71941 atccggtggt gctggcggat accttcctcg ccaacgtgac gctggggcgt gatatctccg
    72001 aagaacgcgt ctggcaggcg ctggaaaccg tgcaactggc ggagctggcg cgtagcatga
    72061 gtgatggtat ttacacgccg cttggcgagc aggggaataa tctctcagtc gggcaaaagc
    72121 aactgctggc actggcgcgc gtgttggtgg agacgccgca aatcctgatc cttgatgagg
    72181 caacagccag cattgactcc ggtactgaac aggcgattca acatgctctg gcggcggtgc
    72241 gtgagcatac cacgctggtg gtgattgctc accgcttatc aactattgtt gatgccgaca
    72301 ctattctggt gcttcatcgt gggcaagccg tggagcaggg cactcaccag caactgctgg
    72361 cggcccaggg acgctactgg cagatgtatc aactgcaact tgcgggcgaa gagctggcag
    72421 ccagcgtgcg tgaagaggaa tcattgagcg cctgaatagc gcaatatttc atcgttggtg
    72481 caaaaatgta acgcactgtg cactgtcata gtgcgttttc attttcaatc ttcttaactt
    72541 cctgctctct ttctcgtttt tcatttctgg cacaccgctt gcaatacctt cttcgtgtag
    72601 cagaaccatt accgaattct gaccggaggg gatctatgaa gctggtgacc gtgataatca
    72661 aaccattcaa gctggaagac gttcgtgaag cgttatcttc cattggtatt cagggcctga
    72721 ccgtcaccga agtgaaaggt ttcgggcgtc agaaaggaca tgccgagctg taccgggggg
    72781 cggaatacag cgtcaatttc ctgccaaaag taaaaattga tgtggcgatt gctgatgacc
    72841 aactcgatga agtgatcgat atcgtcagta aggcggctta caccggaaaa attggcgacg
    72901 gcaaaatctt cgtcgctgaa ttgcaacgcg tcattcgtat tcgtaccggc gaagccgacg
    72961 aagcggcgct gtaatctctg gcacacagca acaggaacga aaaatgaaga tagcgacgat
    73021 aaaaactggg cttgcttcac tggcgatgct gccgggactg gtaatggctg cacctgcggt
    73081 ggccgataaa gccgacaatg cgtttatgat gatttgtact gcgctggtgc tgtttatgac
    73141 tattccgggg attgccctgt tttacggtgg gttgattcgc ggcaaaaacg tgctgtcgat
    73201 gctgacgcag gtgacggtga cgtttgcact ggtctgtatt ctctgggtgg tttacggtta
    73261 ctcgctggcg tttggtgagg gaaacaactt cttcggcaac attaactggt tgatgctgaa
    73321 aaatatcgaa ctgacggcgg tgatgggcag catttatcag tatatccacg tagcgtttca
    73381 gggatcgttt gcctgcatta ccgtaggctt gatagttgga gcactggcgg aacgaatccg
    73441 tttctcagct gtgttgattt tcgtggtggt atggctgacg ctctcctaca ttccgattgc
    73501 gcatatggtc tggggcggcg gtttgctggc ttctcacggt gcactggatt ttgcgggtgg
    73561 cactgtggtg cacattaacg ccgcaatcgc cggtctggtg ggcgcgtatc tgataggcaa
    73621 acgcgtgggc ttcggcaaag aggcgtttaa accgcacaac ctgccgatgg tcttcaccgg
    73681 gactgccatt ctctatatcg gttggtttgg ctttaacgcc gggtcagcgg gcacggcgaa
    73741 tgaaatcgca gcactggcat ttgtgaatac tgtggtcgca acggcggcgg caattcttgg
    73801 ctggatcttc ggtgaatggg cgctgcgtgg taagccttca ctgctgggag cgtgttcagg
    73861 cgcgattgcc ggtctggtcg gcgtgacgcc agcgtgtggc tacattggtg ttggcggcgc
    73921 gttgattatc ggcgtggtag ctggtctggc gggcttgtgg ggcgttacca tgctcaaacg
    73981 cttgctgcgg gtggatgatc cctgcgatgt cttcggtgtg cacggcgttt gtggcattgt
    74041 cggctgtatc atgaccggga tttttgccgc cagttcgctg ggtggcgtgg gcttcgctga
    74101 aggtgtgacg atgggccatc agttgctggt acagctggaa agcatcgcca ttacgatcgt
    74161 ctggtccggt gtggtggcat ttattggcta caaactggcg gatctgacgg ttggcctgcg
    74221 tgtgccggaa gaacaagagc gagaagggct ggacgtcaac agccacggcg agaatgccta
    74281 taacgcgtaa caagcactgc aaaaaacagc cggacggttt tcacctccgg ctattttttt
    74341 aattgtgatt acgcattacc ccttcctgaa cggtcgaggc aaccagcacg ccgtcctgag
    74401 tataaaactc accgcgcaca aagccgcgtg cgctggacgc cgaggtgctt tccacgctat
    74461 acagcagcca ttcattcaaa ttaaacgggc gatggaacca catggaatgg tcaatggtgg
    74521 caatctgaat ccctggttcg agaaaaccga tgccgtgcgg ctgtagagct accggcagga
    74581 agttaagatc agaagcgtaa ccgagcagat actgatgaac gcgcagatca tccggcacgc
    74641 taccatttgc gcggatccac acctgacgat gcggttctgc gacgtgccct ttcagtgggt
    74701 tatgaaactc caccggacgg acttcaagcg gacgatcgca gatgaattta tctttcagca
    74761 ctggcggcag caggtgcgcc agcgattggg cgatttgcgt ttccgaaggc aggccatcag
    74821 gcgctggcgc ggacggcatt gttttttgat gttcgaaacc cgcttctggt gcctggaaag
    74881 aggcagtcat ataaaaaatc ggtttgccgt tttgaatagc agcaacccgg cgggcgctga
    74941 agctgttacc gtcacgcagc gtttcgacat cataaataat cggtttctta ctatcgcctg
    75001 ggcgaagaaa gtagctgtga aacgaatgta ccagccgctc ttcagggacg gtctcttttg
    75061 cagcatacaa ggcctgaccc acgacctggc cgccaaacac ctggcgtaaa cctaaatctt
    75121 cactctggcc gcgaaagagt ccttcctcaa ttttttccag atttaacaat gtcagtaaat
    75181 tttttagcgc ctgactcata taactctcca gtaacaaagc tgccgcagca agccaaagtg
    75241 agttgagtat aacgcaaatt tgccactggt ccgatgggtg caatggtctg aattacgggc
    75301 taattacagg cagaaatgcg tgatgtgtgc cacacttgtt gacgttacta ttttgttaac
    75361 cactcttccg gcgaggaaag ttagcccgct ggtgcattga taataaggag aagtgaatga
    75421 aactcgtgca catggccagt ggtttagcgg ttgcgattgc gttggcggct tgcgcagata
    75481 aaagcgcgga tattcagacg ccagcaccgg ctgcaaatac gtctatttca gcaacacaac
    75541 aacctgctat ccagcaaccg aatgtctccg gtaccgtctg gatccgtcag aaagtcgcac
    75601 tgccgcctga tgctgtgctg accgtgacac tttctgacgc gtctttagcc gatgcgccgt
    75661 cgaaagtgct ggcgcagaaa gcggtgcgta ccgaaggtaa acagtcacca ttcagctttg
    75721 ttctgccatt taacccggca gatgttcagc cgaatgcgcg tattctgttg agtgcggcga
    75781 ttaccgtgaa tgacaaactg gtatttatta ccgataccgt tcagccggtg atcaaccagg
    75841 gcggaactaa agccgacctg acattggtgc cggtgcagca aaccgccgtg ccggttcagg
    75901 ccagcggtgg cgcaacgact accgtacctt cgacttcacc aactcaggtg aatccgtctt
    75961 cggcagttcc agctcctacg caatattaag cgcagttaac cctctccgcc cggagagggt
    76021 tagtagttcc agcgataacg ctgcaagtcg atttgcccgc ttcccgatac catcacacct
    76081 tctgccagta atgcctgtcg ttgacgctgt aaatccggtc cggttagcga aattgtgccg
    76141 tggcgattaa ccacccggtg ccagggcaag gtgctgcctt cagggagacg ctttaacaca
    76201 ccgcccacct ggcgcgcggc gcggggcgat cctgccagtt tcgccacatc accgtaagtg
    76261 gtgacatagc cttcgggaat agcggcgacg atttgccaga cgcgttgggg aaatgaatct
    76321 tctttttcca tcttttcttc ctgaggtaat ttttcagcat aatctggaaa aacgcccgag
    76381 tgaagccgca ttgcgcaaga aaccagcatc tggcacgcaa tgggttgcaa ttagccgggg
    76441 cagcagtgat aatgcgcctg cgcgttggtt ctcaacgctc tcaatggggg ctctgttggt
    76501 tctcccgcaa cgctactctg tttaccaggt caggtccgga aggaagcagc caaggcagat
    76561 gacgcgtgtg ccgggatgta gctggcaggg cccccaccca tttctgcctc cccccgtttc
    76621 gtcaaaaaat cccaatatgg ctaaacttta accacaactg acgtcgcaag aattgtctgg
    76681 ctgcgcagta cgcttcggag gtatgtctga tgaagtatgt tgatggtttt gtggttgccg
    76741 ttcctgccga taaaaaggat gcctatcggg aaatggctgc taaggctgcg ccattgttta
    76801 aagagtttgg cgcgcttcgt attgtcgaat gctgggccag cgatgtaccg gatggtaaag
    76861 tgaccgattt tcgtatggcg gtgaaagcgg aagagaatga agaggttgtc tttagctgga
    76921 ttgaataccc ttcaaaagag gtccgcgacg ctgctaatca aaagatgatg tcggacccac
    76981 ggatgaaaga gttcggcgag tccatgccgt ttgatggcaa gcgaatgatc tatggcggat
    77041 tcgagtcaat catcgacgaa taggtagcgt gacgggctgt gcggcgtgcc gtcagcccaa
    77101 aaattcacaa atgttgctcg gcccagcgta agaaatcctc tttcggtaat gccttgctgt
    77161 agagccagcc ctggccgtag tgcacgccat gctggcgtag ccactcttct tgtttactgg
    77221 tttcgattcc ctccgctacc attttcagtt tcagtgtttt tgccatttcg atgatatgtg
    77281 gcgtgacatt tttatattcc agcgcatcaa cgaaagattt atcgatcttc agaatgtcga
    77341 catccagatc ctgtaaatag cttaaacttg aataccccgt accaaaatca tcgagataaa
    77401 tttcatggcc cgcctcccgg tagcgagaaa ttatcggggc gctggttttc ggatcggcaa
    77461 actcgcgttc agtgagttca agcgcgatct gtctgggatt aacctgatag tgattgatca
    77521 tttcacgcag caattgcggg attttttccg aggtgagcac ggtggattca agattgatcg
    77581 aaatatgctg ctgcggatgc tgacgcagcc agtcgcccat atcttcaaag acacttttta
    77641 taatcagtag cgtcaacggc tcagaaagcc ccgtttgctg tgccagcgga ataaaactat
    77701 ctggtgacaa ccaactaccg tctgtctgcg gccagcgcgc cagtgcctca gcaccgacaa
    77761 ttttgccatt ggctaaggag acaatcggct gatagtgcac gcaaatatca cgattttcga
    77821 tagcatcctg cagccgatga tgcggtgact ggatacggcg caaaatacgc agcacaaaca
    77881 tcgctgccag caggccaatc accaacccga gcggtaacca aataaagact tgccgatgcc
    77941 agcctttctg caacattttc gttgaagccc aggtgatgat cgaaatattc atctccggta
    78001 agggcaggat atcgtaaatg attccattat tttcgatatg ctcaccgggt gttttttgta
    78061 gtctggtaat aattccctga gcaatttcat cgctgctggt tatcacaacg ttatgggcat
    78121 tgccaataat ggcggcatca atttgccatg agctataggg aatgacatca ataaaggaag
    78181 cggggtcgat catgacgaca taatgtgccg ttcccatggc gaccatgtaa cggataatgc
    78241 ctaaatcgtt atgcgatgtt aaccagacac gataaccatc tttcgaaatt ttacctggct
    78301 cggggaaggc atcgggtggg ctttcatgct ccagagacga acacagggga acgttgttat
    78361 cgatataaac cacttcctga atatagcgat aactgtaaga tacccgacgc atttccatga
    78421 gatgggctgc gctacaggca gcgccttgcc atctttccag ctcttgcagc gcatctttcc
    78481 cttgtgtcgc caccttattg gcccgaatag cgacgcggga ggaatacgta ttcagctctt
    78541 caataaatga tgtttctacc tgctgatggg ccagccagat gcttaagccg acaggcagca
    78601 atactgaaag aatcagtact cccgaaataa ggccgaccag atgtcgtgtt ctcaccagca
    78661 tatccttatt aacacagtgt agggaaagta tatctgattg tggaaaaagg ctggcaggag
    78721 ataaggaggt agagccggga tttcatgaag tgatgggtgg aaacgaacgt tgtcatttga
    78781 ccaggcgcag agctttacgc ctggtatgta accctaactt aagatgttga ttcggcgcga
    78841 gcgagggtaa aaatatcgta aaaagacagt tcacctttac ggacgagcat tttttgcagt
    78901 tgttctttat gaacatccgc gacacgcgga gagttcaaga tggcttcaac cagcgcggca
    78961 ggtacaaagc gcgtgttgta ccattcgccg ttatagcaaa cgcggaaatc cagcacgtcg
    79021 atatcttcat agcggtagcg tgggtagaca tcgaaaaaga agaaaccatt cagcaggata
    79081 aataatacaa ccagtagcca gacagagcct gaaagcgttt cggactgcaa catcaccgcc
    79141 agggtggcaa aaaaagcaac gtacataccg ataaacagcc ccggatgttt acggataaaa
    79201 ctgatactaa agcggggttt gttgtcgcgt ttttcgcggg tattcagaga ctcaatcgtt
    79261 tcggtcagca ggcgttgtat ttcggtcatc gtttgccttc gtggtatctg caactttcca
    79321 gggaacaccc tattttaacg tgggaatagt agagggaaag taacagattt gccacgattt
    79381 tgcataacag ttgcgaaaaa ctggttacaa ttttttaatt attctggctg gattaccgcc
    79441 cacgacaacg ttgtccggga catcttttgt gacaactgca cctgaggcta ccacgacgtt
    79501 atcaccaatg gtcacaccag ggttaatgat cgcgcgtccg ccaatccaga cgttattacc
    79561 gatggtgacg ggtttcccca gttcagcacc gctattacgt gctacagggt cgatgggatg
    79621 tgttgccgtg tagatatgaa cgcctggtgc caacatacag ttatcaccga tgcgaatagg
    79681 gcagacatca agcatcacgc aatcgaagtt ggcgaaaaaa ttattgccga gaaaaatgtt
    79741 atagccataa tcacagcgaa acgttggctc aatataagcc tctgtcacct gaccgaataa
    79801 ttcagcgaga atttgctggc gtaatgtgtg ctcttccgcc agggaatgat tgtatcggtg
    79861 aataagctga cgagcgcgca ggcgatcgcg agataacgtc tcatctgccg agcgatacaa
    79921 ctcaccagca atcatctttt ctttttctgt gctcattact gacctccggt tgctgaaaat
    79981 gcggcaacac agtaagacga aaagtcagtg aagagaacgt tcccattacg tctgtgtgat
    80041 gaagatcaca tagggtatgc cttcatggcg ataaagtata aaattcttaa taaacagctg
    80101 gttatagctc cgaaagccaa ttatttatta gcgaataaat ttccatactg aggaagggat
    80161 cttgtcgtac agtttattca tagtcaattc ggcgaggcgg tgatctgcgg ctgagtaaaa
    80221 taccgccagt tcattatctg ataattcgta tttatttttc tcgataacac gctccagcgt
    80281 gtcaattgtc tggcaacgac gtaaacgcat taaataatcg gttttcgtta aaggtttttc
    80341 ggacatactt ctacccatgg ttgtaataat tctaacaaga taaactcgca ggattctctt
    80401 tcgtcgcatt gacaaaacaa cggaatagtc gattacctga cttccgccat ttctgaagat
    80461 cctgcatatt aataccataa ctgctgaaca acataaaggt gtcatccaga tattcgtcga
    80521 tctgctcaat gagcttattg tcttcattat acttaatttt gtaattaagt gcgaaggtcg
    80581 caatatgctc aatcagttca ttcaactgga ggttgatcgc cgaggttggg tcgttaaccc
    80641 agccatgatt gctttcttca aggtttgcaa gacagtcatg atacagggtt tcacagagaa
    80701 acttaagctg tgcgatatca tgtcttttgg gtgagtattc atccataacg cgtccccttc
    80761 ttagcggttg aactaacgga cacctttcgg gatggaaaaa acttactgac ctggacttgc
    80821 cctctcgttt gttagcttaa ctataagcca ctctttgcag gttttcatcg cattattacg
    80881 aaaaattaca attaggaagg aagcgggaca ggacttactt tttcatacta gcactaaccc
    80941 gcagcaggta aaagcagttt gctcgaactg ttcataacat ttcaggatta tcgccagatg
    81001 aaattggtaa cactaatacc aggattgctc tgaatatgac gtaataaccg aggaatgaat
    81061 aaagaattac cgcaaataat taagaatagc ctctaaatga ttatggatta ttaaatctat
    81121 tagcgctact taatataaat taactaacaa tcagtatttt ttatgaattt tatacgtgtt
    81181 taatactggt tttcgtatga gatcctgagt tggtggttca atgactcctt aatgttcgta
    81241 ggttatgcat aaaaaaggcc gcttgcgcgg ccttagtgat tacacgttgt atcaatgatg
    81301 atcgacagta tggctgtgct cgatatcttc attcttgcgg ctaaagcggc ggcgaaccac
    81361 cacaaagaat accggaacga agaagattgc cagtaccgtt gcggtcacca tcccgcccat
    81421 tacaccggta cctactgcat tctgtgcgcc ggaaccagca ccagtactga taaccagcgg
    81481 cataacgccg aggataaacg ccagcgaggt catcaggatc ggacgtaaac gcatccgcac
    81541 cgcatcaagc gtcgcttcaa tcagaccttt accttcttta tccatcaagt ctttggcgaa
    81601 ttcgacgata agtatcgcgt tcttcgccga caacccaatg gttgtgagca ggcctacctg
    81661 gaagtaaacg tcattggtca ggccacggaa ggtggcagcc agcaacgcac cgataacccc
    81721 cagcggaacg accagcataa cggagaacgg aatcgaccag ctctcgtaca gcgccgccag
    81781 acacaggaac acgacaatca acgaaatcgc gtacagtgaa ggtgcctggt tgccggagag
    81841 acgttcctga taggacatcc ccgtccagtc atagccaaca ccggtaggca gtttgctcgc
    81901 cagttgttcc atcagctcca ttgcttcacc ggtactttta cccggtgccg cctggcctaa
    81961 gatttccatg gatggcaggc cgttgtaacg ttccagacgc ggcgaaccgt actcccaacg
    82021 agaagaggag aacgccgaga acggcaccat ctgaccatca gcagcacgaa cataccagtc
    82081 gccgatatca tccggcagca tacggtattt cgcttctgac atgacgtaaa ctttcttcac
    82141 acgaccgcgg tcgataaagt cgttcacata gctaccgccc catgcagcgc ccagagtggt
    82201 gttaatgtcg ttgatagaaa cacccagcgc ctgcgctttt tcctggtcga tatcaatctt
    82261 aaactgcggg gtatcttcca gaccgtttgg acgtacgctg gtcaacatat cagggtgctt
    82321 cgctgcttct gcaagcagct ggttacgcgc ctgagtcagt ttttcgtgac caaggccagc
    82381 ctggtcaatc agctcaaagt caaagccggt tgcggtaccc agttccacga ttgcgggcag
    82441 gttaaaggcg aaaaccatcg catctttgat ttgcgagaaa gcacgtgttg cacgcatggt
    82501 aatcgcttca actttgtttt cttcgcccgg acgatcggcc cagtccttca aggaaacgaa
    82561 cgcaataccg gtattctgac cacgtcccgc aaagccgaag ccgttaacgg cgaacaccga
    82621 ctcaacgttg ttcttttctt tggtcagata gtaatgcgtt acctcattga gcactttctg
    82681 cgtacgttcc tgcgttgcac ctgctggcag ctgaaccatg gtcataaata cgccctggtc
    82741 ttcatctggc aagaaggagc ttggcagacg cacgaacaga taggccatgc cgaccacgat
    82801 gatcagatac agcaccaggt aacgccctgt actgcgcaga ataccgccta cgctgtcggt
    82861 gtagtggtgc gtgctctttt cgaacatgcg gttaaaccag ccgaagaagc cttttttacc
    82921 ttccccgtga tcgcctttgg caatcggttt cagcatggtg gcacaaagag ccggagtcag
    82981 gatcaacgcc accagtactg acagcgccat tgctgaaaca atggtaatag agaactgacg
    83041 ataaatagca ccggtagaac cgccaaagaa ggccatcggt acgaataccg ccgacagtac
    83101 catcgcgata ccgaccagag cgccctgaat ctgccccatc gacttacggg tagcttcttt
    83161 tggcggcaaa ccttcttccg ccataacacg ctcaacgttt tctaccacaa cgatggcgtc
    83221 atccaccaac aggccgatgg cgagcaccat cccgaacatt gttagcgtgt ttatcgagaa
    83281 gccaaaggcg gcaaggacgg caaaggtccc cagcaatacc accggtacgg caatggtcgg
    83341 aatcaacgtc gcgcggaagt tctgcaggaa cagatacata accaggaaca cgaggatgat
    83401 cgcttcgacc agcgttttaa ccacttcgtg aatagagatt ttcacgaacg gcgtggtgtc
    83461 atacgggtaa acaattttca gacccgacgg gaagaacggt tccatcttcg ccagttcagc
    83521 acggattgcc gcagcggtat ccagcgcgtt cgcaccggtc gccagcttga tccccagacc
    83581 ggaagccggt tggccgttaa actctgcgat gatgtcgtag ttctcaccac ccagctcaat
    83641 tttcgccaca tcacgcagca gcacgcggga accatcctga ttcactttca gcaggatttt
    83701 gccgaactct tcagtagagg tcagacgtgt ctgagcaata atagaggcgt taagctgttg
    83761 gcctttcacc ggcggcgtac caccgagctg acccgccgca acctgggcgt tctgcgcttt
    83821 gatggcggta atgacatcaa ccggtgttag ctggaatttg tttagttcat tcgggttcat
    83881 ccagatacgc atcgcgtact gtgaaccgaa caactgaacg tcacccacgc ccgacgtacg
    83941 gctgatggca tctttcatat tcgccgccac gtagtcggag atatcctcct gcgtcatggt
    84001 gccatcggtg ttgataacgc cgacaaccat caggaagctg ctggatgatt tctcaacgct
    84061 caccccttgc tgctgtactt cttgtggcag caacggcatc gccagctgca gtttgttctg
    84121 cacctgaacc tgcgcgatat ccgcatcagt accagactca aaggtcaggg tgatctgcac
    84181 ggtacccgtg gagtcactgt tagaggacat gtacatcagg ttatcgatac cgttcatatt
    84241 ctgttcgata acctgtgtca ccgtgtcctg cactgttttc gcatcagcgc cagggtagga
    84301 ggcggagatc gttactgccg gcggtgcaat cgtaggatat tgcgccaccg gcagtttgag
    84361 gatcgccagc ccccctgcca acatgatgat aatggcgatc acccacgcaa aaatcgggcg
    84421 atcgataaag aaattaggca tgtcttaacg gctcctgttt aagttaagac ttggactgtt
    84481 caggctgagc accgcttgcg gcttgctggt tattatcagc ggtaacttct tgtgctttta
    84541 cctggacacc aggacgcact ttctgcagcc cacttattac tacgcgatcg cctgctttca
    84601 gaccttctgt caccagccac ttatcgccga tagcctggct tgcaacgatc ggacgggttt
    84661 ccactttgtc atccgcgcca accaccagta cggtggcatc gccacgcggc gtacgggtta
    84721 cgccctgttg cgggactaaa atagcgtttg gattaagccc ttcttccaga cgtgcacgta
    84781 cgaacatacc cggcagcaga gtgtgatccg ggttcgggaa gatagcgcgt agggtgatag
    84841 acccggtggt ctgatcaacg gtaacgtcag agaattccag cgtaccgtcc tgcgggaact
    84901 taatgccgtc actggtgatc agcgacactt tggctttgcc gttctcttgt ttcagcgtgc
    84961 catttgccag ttcctgtttc aggcgcagga agtcgttgct ggactgggtc acatcaacgt
    85021 agatcggatc aagttgctgc acggttgcca gcgcagtcgc ctgaccgttc tgtaccaatg
    85081 cgccttctgt cacgttcgac ttaccaatgc gaccgctaat cggagaggtg actttggtgt
    85141 aagccagatt gatccgcgca gtttcaacgg cagctttcgc cgcagtgacc gcagcattcg
    85201 cctgttgcgc atcagccaga gcctgatcgt actcttgttt actgatgtac tgagtaccga
    85261 gcagtttctg ataacgattc accgtcaatt gcgcgatatt tgctgcagcc tgggctttcg
    85321 ccagatcacc tttcgcactg tcgtatgccg cctgataggt cgcaggatca atctgataga
    85381 gagagacacc tgcttcgatg tcgctacctt ctttgaaatt acgcttcagg ataatcccgc
    85441 taacttgagg acgaacttct gcgatccggt aggcactggt gcgacccgga agctcggttg
    85501 tgatctgcag aggttcagtt ttgactgtta ctacgccaac ggcgggcatc tgctggccac
    85561 cttgttgggc ctgtttgtcg tcacatcctg ttagggctaa gctgcctgag agcatcagaa
    85621 cgaccgccag aggcgtaaac cctctgtttt tgttcatatg taaacctcga gtgtccgatt
    85681 tcaaattggt caatggtcaa aagttaataa acccattgct gcgtttatat tatcgtcgtg
    85741 ctatggtaca tacattcaca aatgtatgta aatctaacgc ctgtaaattc acgaacatat
    85801 ggcacgaaaa accaaacaag aagcgcaaga aacgcgccaa cacatcctcg atgtggctct
    85861 acgtcttttc tcacagcagg gggtatcatc cacctcgctg ggtgagattg caaaagcagc
    85921 tggcgttacg cgcggtgcaa tctactggca ttttaaagac aagtcggatt tgttcagtga
    85981 gatctgggaa ctgtcagaat ccaatattgg tgaactagag cttgagtatc aggcaaaatt
    86041 ccctggcgat ccactctcag tattaagaga gatattaatt catgttcttg aatccacggt
    86101 gacagaagaa cggcgtcgat tattgatgga gattatattc tacaaatgcg aatttgtcgg
    86161 agaaatggct gttgtgcaac aggcacaacg taatctctgt ctggaaagtt atgaccgtat
    86221 agaacaaacg ttaaaacatt gtattgaagc gaaaatgttg cctgcggatt taatgacgcg
    86281 tcgcgcagca attattatgc gcggctatat ttccggcctg atggaaaact ggctctttgc
    86341 cccgcaatct tttgatctta aaaaagaagc ccgcgattac gtcgccatct tactggagat
    86401 gtatctcctg tgccccacgc ttcgtaatcc tgccactaac gaataaccct gaatctaact
    86461 ccaggatttt tcctggacat tttcgtcgtt gctattctgg ttcactgcgt cgtgatattc
    86521 ttgcggtttg actttttcag gtcgttcttc aggttcagaa accttcattc atcatgacta
    86581 tgttccagta ttacaaacga tcacggcatt ttgttttttc agcatttatt gcttttgttt
    86641 ttgtcttgtt atgccagaac acggcgtttg cgcgggcgtc atcgaatggt gatctgccga
    86701 caaaagcgga cctgcaggca caacttgact cactgaataa acaaaaagat ctttctgctc
    86761 aggacaaact ggtgcagcag gatctgacag atacattagc caccctcgat aaaatcgatc
    86821 gcgtaaaaga agagacagtt cagctacggc aaaaagtcgc tgaagcgccg gaaaaaatgc
    86881 gccaggcgac cgcggcgtta acagcactta gcgatgtcga taacgacgaa gaaacgcgca
    86941 aaattctgag cacgctttcg ttgcgccagc tggaaactcg cgttgcccag gcgctggacg
    87001 atttgcaaaa cgcacaaaac gatctggcgt cttataacag ccagctggtt tcgttacaga
    87061 cgcagcccga acgcgtgcaa aatgcgatgt ataacgcttc gcagcagctg caacaaattc
    87121 gcagtcgtct ggacgggact gatgtcggcg agactgcctt acgtcccagc cagaaagtgt
    87181 taatgcaggc tcagcaggct ttgctgaatg ccgagattga ccagcagcgt aaaagcctgg
    87241 aagggaacac cgtcttgcag gataccttgc aaaagcaacg tgattacgtg acggcgaaca
    87301 gcgcccgtct ggagcaccag ttgcagctgt tgcaagaagc agtaaacagc aagcgtctga
    87361 ctttaaccga aaaaacggcg caggaagccg tctccccgga tgaagccgcg cgtattcagg
    87421 ctaatccgct ggtgaagcag gaactggaaa ttaaccagca gttaagtcag cgtctgatta
    87481 ccgcgactga aaacggtaat cagttgatgc agcaaaacat taaagtcaaa aactggctgg
    87541 agcgggcgct gcaatcggaa cgcaatatta aagagcagat tgccgtcctg aagggcagcc
    87601 tgctgttgtc tcgtatcctt taccagcaac aacaaacgct gccctcggcg gatgaactgg
    87661 aaaacatgac caaccgcatc gcggatttgc gtctcgaaca gtttgaagtt aaccagcagc
    87721 gtgatgcact cttccagagc gatgcgttcg tcaacaaact ggaagaaggt cacaccaacg
    87781 aagtcaacag cgaagttcac gatgcgttat tgcaagtagt tgatatgcgt cgcgaattgc
    87841 tggatcagct taacaaacag ttgggtaacc agctgatgat ggccattaac ctgcaaatca
    87901 accagcagca gttaatgagt gtgtcgaaaa acctgaaatc catcctgact cagcaaatct
    87961 tttgggtgaa cagtaaccgt ccaatggact gggactggat caaagcgttc ccgcaaagcc
    88021 tgaaagatga atttaagtcg atgaaaatca cggtgaactg ggaaaaagcc tggcctgccg
    88081 tttttatcgc tttcctcgcc ggtttgccgc tgctgttgat tgccgggctg atccactggc
    88141 gtctgggctg gctgaaagcg tatcaacaaa aactggcttc cgctgtgggt tccctgcgta
    88201 acgacagcca gctcaacaca ccaaaagcga tccttatcga cctgatccgt gcgctgccgg
    88261 tgtgcctgat tattctcgcg gttggcctga ttctgttgac catgcagctc aacatcagcg
    88321 aactgctatg gtcgttcagt aaaaaactgg cgattttctg gctggtgttt ggcctgtgct
    88381 ggaaagtgtt ggagaaaaac ggcgttgccg tgcgtcactt cggcatgccg gaacagcaga
    88441 ccagccactg gcgtcggcaa attgtccgca tcagtctcgc attgctgcct atccatttct
    88501 ggtctgtggt ggcagaactt tccccgctgc atctgatgga tgatgtgctg gggcaggcga
    88561 tgattttctt caacttgctg ctgattgcct tcctggtgtg gccgatgtgc cgcgaaagct
    88621 ggcgtgataa agagtcgcac accatgcgac tggtcaccat taccgtactg tcgattatcc
    88681 cgattgcgtt gatggtgctg accgccacgg gttatttcta caccacgctg cgcctctccg
    88741 ggcgttggat tgaaaccgtt tatttggtga tcatctggaa cctgctgtac cagacggtat
    88801 tgcgcggctt aagcgtagcg gcgcggcgta tcgcctggcg tcgtgcgctg gcgcgtcggc
    88861 agaatctggt gaaagagggc gcagaaggtg ccgaaccgcc ggaagaaccc accattgcac
    88921 tggagcaagt taaccagcag acgctgcgta ttaccatgtt gctgatgttt gcgctgttcg
    88981 gtgtcatgtt ctgggcaatt tggtccgatt tgatcaccgt gttcagctat ctcgacagca
    89041 ttacgctctg gcattacaac ggtactgaag ctggtgctgc ggtggtgaaa aacgtcacca
    89101 tgggcagtct gttgtttgcg attatcgcct caatggtggc ctgggcgttg attcgcaacc
    89161 tgcctggttt gctggaagtg ctggtgctct cgcgactgaa tatgcgccag ggcgcgtcgt
    89221 atgccattac taccatcctt aactacatca ttattgccgt tggtgcgatg acggtgttcg
    89281 gatcgctggg cgtctcttgg gataaactcc agtggctggc agcagcatta tccgtaggtc
    89341 ttggttttgg tttacaagaa attttcggta acttcgtctc cggtttgatc attctgttcg
    89401 aacgtccggt gcgcattggc gatacggtaa ccattggtag cttctcgggg acggtaagta
    89461 agatccgtat tcgtgcgaca acgattaccg atttcgatcg caaagaagtg atcatcccga
    89521 acaaagcgtt tgttaccgag cgtctgatca actggtcgtt gactgacacg actacgcgtc
    89581 tggtgatccg tctcggcgtg gcctatggct ccgatctgga aaaagtgcgt aaagtgttac
    89641 tgaaggcggc gactgagcac ccaagggtga tgcacgaacc aatgccggaa gtcttcttta
    89701 cggcgtttgg tgccagcacg ttggatcatg agctgcgtct gtatgtgcgt gaactgcgtg
    89761 accgtagccg tactgtcgat gagctgaacc gtactatcga tcagctgtgc cgtgaaaacg
    89821 acatcaacat tgcctttaac cagcttgaag tgcatctgca caacgagaag ggcgatgagg
    89881 tgacggaagt caaacgcgac tacaaaggcg acgatccgac accagcggta gggtaaggac
    89941 aataaagggc gacagtgatg ccgcccttta ttttttactc gctttgtgaa gtctcatcgc
    90001 tctgtaactt cttttcataa tcgcgtttta caatatccag cgcgcgcagc acggtgcggg
    90061 ctgggatctg attttcttcc agcagcacaa ttaaatcgac ggccagtttg acatcgtcgg
    90121 gggcattttc cagtgacata ctctctccat tgctagcggg ttaaacgcgc taacctgttt
    90181 tcgatttttt ccagcgcatg gcgacaccgc gccaggcgcg cttcataggc ttccacttca
    90241 cgatgcagcg tttgctgttc cacgagatcg gtcacccgcg ccaggcgggc tcgacgttcg
    90301 gctaccatct cacgtagccg ccgctcaaaa tcctgatgct gaatacgttt acgctgccag
    90361 cgggcaattt tcggtggtgc gctatcccac tcgcgtagcg accaggctgt ggcttcacgc
    90421 gctatagcct ccagttgcgc cgccagatgt tctgccagcc aggcggcttg cggcagctgt
    90481 tgctgctcaa ccgcatgacg aagcgcagcc aggttatcgc ctgcctcatc gagacaagcc
    90541 tgcagtgttg tcgcacgggt ctgaaaaagg tgcctgtcaa aacgggcact tagcgtggca
    90601 aattgcgcta ccggggcaca acgctgacgc agcgtggcga gctgtccttc cagtttttcc
    90661 agcagcaggg tggttttcac gataagacct caatgaaaat gataattgtt atgctaaagt
    90721 agccactctg taagctgaca acactcaata tgcaacgaat cattttaatc atcattggct
    90781 ggctggcggt agtgctgggt acgctgggcg tggtattacc ggtattaccg acgacgccgt
    90841 ttatcctgct ggcggcctgg tgctttgccc gttcttcccc gcgctttcac gcctggttgc
    90901 tgtaccgctc atggtttggc agctatctac gtttctggca gaaacatcat gcgatgccgc
    90961 gcggcgtcaa accgcgggcg attatgctta ttttgctcac gtttgccatt tctctgtggt
    91021 tcgtccagat gccatgggtg cgcatcatgt tgctggtaat tctcgcctgt ttgctttttt
    91081 atatgtggcg aattccggtg attgatgaaa agcaagaaaa gcactgaagc acaacaatcg
    91141 cagttgcaat tattgcgtac agccagtaca ttctggcgtt ttcgagcaca ggcgcaggcg
    91201 gtcaaaggtt aaacaactgt tacttttgat acgtttaaaa cgcgccgtga gtaccaccgt
    91261 aacaagcagg catacactta tgaccgcgac tgcacagcag cttgagtatc tcaaaaatag
    91321 catcaaaagc attcaggact acccaaaacc cggcattctt ttccgcgatg tcaccagctt
    91381 actggaagac ccgaaagctt acgctctcag catcgacttg ctggttgagc gttacaaaaa
    91441 tgcgggcatt accaaagtgg tcggcaccga agcgcgtggc ttcttgtttg gcgctccggt
    91501 agctctgggt ctgggcgttg gctttgtacc ggtccgtaaa ccgggcaaac tgccgcgtga
    91561 aaccatcagt gaaacttacg acctggaata cggcaccgat cagctggaaa tccacgttga
    91621 tgccatcaaa ccgggcgaca aagttctggt ggtggacgac ctgctggcaa ccggcggcac
    91681 tatcgaagcg accgttaaac tgatccgtcg tctgggtggt gaagtggctg atgctgcgtt
    91741 cattatcaac ctgttcgatc tcggcggcga acagcgtctc gaaaaacagg gcattaccag
    91801 ctacagcctt gttccgttcc cgggccatta attatcgcca gtcttgtgct gcccacgcta
    91861 cggacagcac aagatgtgca ttcagcctcg ccgttctgac ggggctgtgt tagcattacc
    91921 ccttcgtgaa tccaccttcc agcgtttcag agcctgccaa tgagttatca ggtcttagcc
    91981 cgaaaatggc gcccacaaac ctttgctgac gtcgtcggcc aggaacatgt gctgaccgca
    92041 ctggcgaacg gcttgtcgtt agggcgtatt catcatgctt atcttttttc cggtacccgt
    92101 ggcgtcggaa aaacctctat cgcccgactg ctggcgaagg ggctaaactg cgaaaccggc
    92161 attaccgcga cgccgtgcgg cgtgtgcgat aactgtcgtg aaatcgagca ggggcgcttt
    92221 gtcgatctga ttgaaatcga cgccgcctcg cgtaccaaag tcgaagatac ccgcgacctg
    92281 ctggataacg tccagtacgc tccggcgcgt ggtcgtttca aagtttatct catcgacgaa
    92341 gtgcatatgc tgtcgcgtca cagctttaac gcactgttaa aaacccttga agagccgcca
    92401 gagcacgtta agtttttgct ggcgacgacc gatccacaga aattgccggt gacgattttg
    92461 tcacgctgtt tgcaatttca tctcaaggcg ctggatgtcg agcaaattcg ccatcagctt
    92521 gagcacatcc tcaacgaaga acatatcgct cacgagccgc gggcgttgca attactggcg
    92581 cgcgccgctg aaggcagcct gcgagatgcc ttaagtctga ccgaccaggc gattgccagc
    92641 ggtgacggcc aggtttcaac ccaggcggtc agtgcgatgc tgggtacgct tgacgacgat
    92701 caggcgctgt cgctggttga agcgatggtc gaggccaacg gcgagcgcgt aatggcgctg
    92761 attaatgaag ccgctgcccg tggtatcgag tgggaagcgt tgctggtgga aatgctcggc
    92821 ctgttgcatc gtattgcgat ggtacaactt tcgcctgctg cacttggcaa cgacatggcc
    92881 gccatcgagc tgcggatgcg tgaactggcg cgcaccatac cgccgacgga tattcagctt
    92941 tactatcaga cgctgttgat tggtcgcaaa gaattaccgt atgcgccgga ccgccgtatg
    93001 ggcgttgaga tgacgcttct gcgcgcgctg gcgttccatc cacgtatgcc gctgcctgag
    93061 ccagaagtgc cacgccagtc ctttgcgccc gtcgcgccaa cggcagtaat gacgccaacc
    93121 caggtgccgc cgcaaccgca atcagcgccg cagcaggcac cgactgtacc gctcccggaa
    93181 accaccagcc aggtgctggc ggcgcgcaag cagttgcagc gcgtgcaggg agcaaccaaa
    93241 gcaaaaaaga gtgaaccggc agccgctacc cgcgcgcggc cggtgaataa cgctgcgctg
    93301 gaaagactgg cttcggtcac cgatcgcgtt caggcgcgcc cggtgccatc ggcgctggaa
    93361 aaagcgccag ccaaaaaaga agcgtatcgc tggaaggcga ccactccagt gatgcagcaa
    93421 aaagaagtgg tcgccacgcc gaaggcgctg aaaaaagcgc tggaacatga aaaaacgccg
    93481 gaactggcgg cgaagctggc ggcagaagcc attgagcgcg acccgtgggc ggctcaggtg
    93541 agtcaacttt cgctaccaaa actggtcgaa caggtggcgt taaatgcctg gaaagaggag
    93601 agcgacaacg cagtatgtct gcatttgcgc tcctctcagc ggcatttgaa caaccgcggc
    93661 gcacagcaaa aactggctga agcgttgagc acgttaaaag gttcaacggt tgaactgact
    93721 atcgttgaag atgataatcc cgcggtgcgt acgccgctgg aatggcgtca ggcgatatac
    93781 gaagaaaaac ttgcgcaggc gcgcgagtcc attattgcgg ataataatat tcagaccctg
    93841 cgtcgattct tcgatgcgga gctggatgaa gaaagtatcc gccccatttg atcgtaagca
    93901 cagcttacgt tcgtcatcct taacgtgatt gagagagaaa cctatgtttg gtaaaggcgg
    93961 tctgggtaac ctgatgaagc aagcccagca gatgcaagaa aaaatgcaga aaatgcagga
    94021 agagatcgcg cagctggaag tcaccggcga atctggcgca ggtctggtaa aagtgaccat
    94081 caacggtgca cacaactgcc gtcgcgtaga gatcgacccg agcctgctgg aagacgacaa
    94141 agagatgctg gaagacctgg tggctgcagc attcaacgac gcagcacgtc gtattgaaga
    94201 aacgcagaaa gaaaaaatgg cctctgtatc ctccggaatg cagctgccgc ctggctttaa
    94261 gatgccgttc tgatgcaaac cagcccgctg ttaacacagc ttatggaagc actgcgctgt
    94321 ctgccgggcg ttggcccgaa gtcggcgcag cgtatggcgt tcacgctgct tcagcgcgat
    94381 cgtagcggcg ggatgcgtct ggcgcaggcg ctcacccggg cgatgtcgga aatcggccac
    94441 tgcgccgatt gccgcacttt caccgaacag gaagtctgta acatctgttc gaatccgcgt
    94501 cgtcaggaaa acggtcaaat ctgcgtggtg gagagtccgg cggacattta cgccattgag
    94561 cagacggggc agttttcagg tcgttatttt gtgttgatgg ggcacctgtc gccgctggac
    94621 ggcatcggtc cggatgacat cggccttgat cgcctggaac agcgtctggc agaggaaaaa
    94681 atcactgaag tgatcctcgc caccaacccc acggttgaag gtgaagctac cgctaactac
    94741 attgccgagc tttgtgcgca atatgacgtg gaagccagcc gaatcgctca tggcgtaccg
    94801 gttggcggcg aactggaaat ggtcgatggc accacgctgt cacattccct tgccgggcgt
    94861 cataagattc gtttttaagc aaacgagagc aggatcacct gctctcgctt gaaattattc
    94921 tcccttgtcc ccatctctcc ctcatcctgt ttttaacctt aaaatggcat tattgaggta
    94981 gacctacatg aaaggacaag aaactcgtgg ttttcagtca gaagtgaagc agcttctgca
    95041 cctgatgatc cattctctct attccaataa agaaatcttc ctgcgtgagc ttatctctaa
    95101 cgcctccgat gcggcggaca agctgcgttt ccgcgcgctt tctaacccgg acctgtacga
    95161 aggtgatggc gaactgcgcg ttcgtgtctc tttcgataaa gacaagcgca cgctgaccat
    95221 ctccgataac ggcgtgggga tgacccgcga cgaagtgatt gaccatctgg ggactatcgc
    95281 taaatccggc accaaatcat tcctcgaatc cctgggttct gaccaggcga aagacagcca
    95341 gctgatcggt cagtttggtg ttggtttcta ctctgcgttt atcgtggccg acaaagtgac
    95401 cgtgcgtact cgcgcggcag gcgaaaaacc agaaaacggt gttttctggg aatcggctgg
    95461 tgaaggtgaa tacaccgttg ccgacatcac caaagaagat cgtggtactg aaatcaccct
    95521 gcatctgcgt gaaggcgaag acgagttcct cgatgactgg cgcgtgcgtt ccatcatcag
    95581 caaatactcc gaccatatcg cgctgccggt agagatcgaa aaacgcgaag agaaagacgg
    95641 cgaaaccgtt atctcctggg agaaaatcaa caaagcgcag gcgctgtgga ctcgtaacaa
    95701 gtcggaaatc accgatgaag agtacaaaga gttctataaa cacatcgccc acgactttaa
    95761 cgatccgctg acctggagcc acaaccgcgt tgaaggtaag caggagtaca ccagcctgct
    95821 gtacattccg tctcaggcac cgtgggatat gcggaaccgc gatcataaac acggtctgaa
    95881 actgtatgtt cagcgtgtgt tcatcatgga cgacgcagaa cagttcatgc cgaattatct
    95941 gcgcttcgtg cgtggtctga ttgactccag cgatctgccg ctgaacgttt cccgtgaaat
    96001 cctccaggac agcacggtaa cgcgtaacct gcgcaatgcg ctgaccaagc gtgtgctgca
    96061 aatgctggaa aaactggcga aagacgacgc ggaaaaatac cagaccttct ggcaacagtt
    96121 tggcctggta ctgaaagaag gtccggcgga agatttcgct aaccaggaag cgatcgccaa
    96181 actgctgcgt tttgcttcta cccataccga ttcttctgcg cagaccgtat ctctggaaga
    96241 ctacgtttcc cgcatgaaag aagggcagga gaaaatctac tacatcaccg cagacagcta
    96301 tgcggcagcg aagagcagcc cgcacctgga actgctgcgt aagaaaggca tcgaagttct
    96361 gctgctttcc gaccgcatcg atgagtggat gatgaactat ctgactgagt tcgacggtaa
    96421 accgttccag tcggtgtcta aagttgacga gtcgctggaa aaactggctg acgaagttga
    96481 tgagagcgcg aaagaagcgg agaaagcact gactccgttc atcgaccgtg tgaaagccct
    96541 gctcggcgag cgcgtgaaag atgtccgtct gactcaccgt ctgaccgata cgccagcgat
    96601 tgtctctacc gacgcggacg aaatgagcac ccagatggcg aaactgtttg ccgcagcggg
    96661 ccagaaagtg ccggaagtga aatacatctt cgaactgaac ccggatcacg tactggtgaa
    96721 acgtgcggca gatactgaag atgaagccaa gttcagcgag tgggtagaac tgctgctgga
    96781 tcaggcgctg ctggcagaac gcggcacgct ggaagatccg aacctgttta ttcgtcgtat
    96841 gaaccagctg ctggtttcct gatgtcatgc cggatgacct ttttgtcatc cggcattttt
    96901 cttttcatca tctgcacttt ccgcaaatta tctcgccatt aaccgtttca gccccaggtg
    96961 cctttcttga ggcaatcgct tgttggtggt atcgtttatc gctttttcaa aaaattcgac
    97021 acattttaag gggattttcg caatgcgtat cattctgctt ggcgctccgg gcgcggggaa
    97081 agggactcag gctcagttca tcatggagaa atatggtatt ccgcaaatct ccactggcga
    97141 tatgctgcgt gctgcggtca aatctggctc cgagctgggt aaacaagcaa aagacattat
    97201 ggatgctggc aaactggtca ccgacgaact ggtgatcgcg ctggttaaag agcgcattgc
    97261 tcaggaagac tgccgtaatg gtttcctgtt ggacggcttc ccgcgtacca ttccgcaggc
    97321 agacgcgatg aaagaagcgg gcatcaatgt tgattacgtt ctggaattcg acgtaccgga
    97381 cgaactgatt gttgatcgta tcgtcggccg ccgcgttcat gcgccgtctg gtcgtgttta
    97441 tcacgttaaa ttcaatccgc ctaaagtaga aggcaaagac gacgttaccg gtgaagaact
    97501 gactacccgt aaagacgatc aggaagaaac cgtgcgtaaa cgtctggttg aataccatca
    97561 gatgactgca ccgctgatcg gctactactc caaagaagcg gaagcaggta acaccaaata
    97621 cgcgaaagtt gacggcacca agccggtggc tgaagttcgc gctgatctgg aaaaaatcct
    97681 cggctaatca agccgcagca gatctgctct cgggcaggtc tgctcatcct cctcaggcaa
    97741 tacctcttac agcaattagt tcttcttctt cacttttccg ctacaattat caacaagttg
    97801 aatcgataag aggcggtaat gcgtcaaaca aaaaccggta tcctgctggc aaacctgggt
    97861 acgcccgatg cccccacacc tgaagcggta aaacgctatc tgaaacaatt tttaagcgac
    97921 agacgtgtgg ttgatacctc acggttgtta tggtggccat tgctgcgcgg cgtgattttg
    97981 ccgctgcgtt cgccgcgtgt ggcgaagctg tatgcttctg tctggatgga aggtggctcg
    98041 ccactgatgg tttacagccg ccagcaacag caggcgctgg cgcaacgttt accggagacg
    98101 cccgtggcgc tgggaatgag ctacggctcg ccatcactgg aaagcgccgt agatgaactt
    98161 ctggcagagc atgtagatca tattgtggtg ctgccgcttt atccgcaata ctcctgttca
    98221 acggtcggtg cggtatggga tgaactggca cgcattctgg cgcgcaaacg tagcattccg
    98281 gggatatcgt ttattcgtga ttacgccgat aaccacgatt atattaatgc actggcgaac
    98341 agcgtacgtg cttcttttgc caaacatggc gaaccggatc tgctgttgct ctcttatcat
    98401 ggcattcccc agcgttatgc agatgaaggc gatgattacc cgcaacgttg tcgcacaacg
    98461 actcgcgaac tggcttccgc actggggatg gcaccggaaa aagtgatgat gacctttcag
    98521 tcgcgctttg ggcgggaacc ctggctgatg ccttataccg acgaaacgct gaaaatgctc
    98581 ggagaaaaag gtgtaggtca tattcaggtg atgtgcccgg gctttgctgc ggattgtctg
    98641 gagacgctgg aagagattgc cgagcaaaac cgtgaggtct tcctcggtgc gggcgggaaa
    98701 aaatacgaat atattccggc acttaatgcc acgccggaac atattgaaat gatggctaat
    98761 cttgttgccg cgtatcgcta aagctgagcg gtaaagaact gagcgccgtc gcgaagagcc
    98821 tcgtcggcgg ttttcatcat ccgtgaataa tgcaaaaagg cgtgcagcgt gcctgggtag
    98881 agtttgaact cacagggctg ctgatgcgcc gctaacgtct ggtaaagcag acggctgtca
    98941 tccagcagcg gatcgaactc cgccccggca ataaaacagg gcggaacttc gcgagtgaga
    99001 tcattattaa acaggcagta atacggcgac tcgcggtccg cgtcgttgct taaatacgcc
    99061 tcttcataca tctgtaaatc ctgttgcgtt aagccatccc agacaccgcc caacagacga
    99121 cgagtcacgg aatcccgtaa tccgtaaagc ccataccaca gcaaaacgcc cgcaacttta
    99181 ccgcaatcga tctgtttatc acgcaaccac aacgcactgg cgagcgccaa catggcacct
    99241 gcggaatcac cggcaaagcc aatgcgggac atattgattt gataatcttc cgcctgctgg
    99301 tggaaataac aacaggcagc cacaatttcc tctatcgctt gcggaaaaca cgcttcaggt
    99361 gaaagggtgt aatcaatgcc aatcaccgta cattggctgt agcttgccag caggcgcatg
    99421 atgcgatcgt gggtatcaag attgccgaga ataaaaccgc cgccatgcaa ataaaatagc
    99481 gtcgccgggc tatctggctg cggacaaaag agacgtgttt ccacctgccc atattttgtt
    99541 ggaaccatgt aagctctggt tgccatttct ggagcgcccg cattccagaa tcggcgctca
    99601 agcgtgtaat gctgtcgttg ctcagcaatc gttcccgttg cgggccaggg cggtaaatcc
    99661 ggctgaagag tattcacaac ggtcttcatt tcagcagaaa taaggtccag aacgggtaat
    99721 ttgttttccg gcttcatgca aaaactcctt tcaaattacg tcattgtaag gaaccactgc
    99781 catgaaaatg cgatcccgcc tgctgatatt gaaactggct gcgtctcgcg cgctcccgtc
    99841 agattgtgtt aacattcgcc gctcagttaa ccacccgtaa aaacaaccat gaaatttccc
    99901 ggcaaacgta aatccaaaca ttattttccc gtaaacgcac gcgatccgct gcttcagcaa
    99961 ttccagccag aaaacgaaac cagcgctgcc tgggtagtgg gtatcgatca aacgctggtc
   100021 gatattgaag cgaaagtgga tgatgaattt attgagcgtt atggattaag cgccgggcat
   100081 tcactggtga ttgaggatga cgtagccgaa gcgctttatc aggaactaaa acagaaaaac
   100141 ctgattaccc atcagtttgc gggtggcacc attggtaaca ccatgcacaa ctactcggtg
   100201 ctcgcggacg accgttcggt gctgctgggc gtcatgtgca gcaatattga aattggcagc
   100261 tatgcctatc gttacctgtg taacacttcc agccgtaccg atcttaacta tctacaaggc
   100321 gtggatggcc cgattggtcg ttgctttacg ctgattggcg agtccgggga acgtaccttt
   100381 gctatcagcc ccggccacat gaaccagctg cgggctgaaa gtattccgga agatgtgatt
   100441 gccggagcct cggctctggt tctcacctct tatctggtgc gttgcaagcc gggtgaaccc
   100501 atgccggaag caaccatgaa agctattgag tacgcgaaga aatataacgt accggtggtg
   100561 ctgacgctgg gcaccaagtt tgtcattgcc gagaatccgc agtggtggca gcaattcctc
   100621 aaagaccacg tctctatcct tgcgatgaac gaagatgaag ccgaagcgtt gaccggagaa
   100681 agcgatccgt tgttggcatc tgacaaggcg ctggactggg ttgatctggt gctgtgtacc
   100741 gcagggccaa tcggcttgta tatggcgggc tttaccgaag acgaagcgaa acgtaaaacc
   100801 cagcatccgc tgctgccggg tgctatagcg gaatttaacc agtatgagtt tagccgcgcc
   100861 atgcgccaca aggattgcca gaatccgttg cgtgtctatt cgcacattgc gccgtacatg
   100921 ggcgggccgg aaaaaattat gaataccaac ggagcagggg atggcgcact ggcagcgttg
   100981 ctgcatgaca ttaccgccaa cagctaccac cgtagcaacg taccaaactc cagcaaacat
   101041 aaattcacct ggttaactta ttcatcgtta gcgcaggtgt gtaaatatgc taaccgtgtg
   101101 agctatcagg tactgaacca gcattcacct cgtttaacgc gcggcttgcc ggagcgtgaa
   101161 gacagcctgg aagagtctta ctgggatcgt taagttatcg accagaccgg acgacgatgg
   101221 catccgtagg ccggataaga tgcgtcagca tcgcatccgg caatggaatc aatgttttac
   101281 cccgtcacca cctcacccgc cggtggcgtt tccagcagtt ccagcatagt acgggcaatt
   101341 tcacgctcac ccatcactac ctgattcgca ccacgttcgg tgatatacgc cacttcatcg
   101401 tcataatggg cgcgggcaat aatctcaata tccggatttt tcgcgcgggc agatgccaca
   101461 atctcgcccg cttcataacc gttgggaatc gtcaggatca gccattttgc acattccaga
   101521 tgcgccagtt gcataatttc ttcgttcgcc gcattgccca atactgcgcg gaccccgcgc
   101581 tctcgcagtt catcaacacg ggttcgtgac gtctcaatca ccaccagcgg aatatcagag
   101641 gcgagcaatt tctcccccag caggctgcct acacgaccgt aacctaccag tagcgcatgg
   101701 ttgcaaatat ccactgggat ctgcttctct tcttcgatag cctcttccag cgtctgctct
   101761 tccagcgttt cggtcttcgc cagatatttc tccagcagcg caaacaggac cgggttgagc
   101821 ataatcgaca aaatcgcccc tgccagtacc aggttctgcc cggcttgcgg caatagatcc
   101881 agcgccatgc ccagtcccgc caggataaac gcgaactcac caatttgcgc caggctggcg
   101941 gcgatagtta atgccgtacg ttgggagtga ccaaacagtc gcaccaggaa aaacgcggct
   102001 aacgacttac caaacagaat aatcgccagc gtcgccagca ctgccagcgg ttgctgaatc
   102061 agaattaacg gatcaaacaa catcccgacg gagacaaaaa acagcaccgc aaacgcgtcg
   102121 cgcaatggca gcgtatcgtg ggcggcacgg tgactcagtt cagactcgtt cagtaccatc
   102181 ccggcaaaga acgcaccgag tgcaaaggag acatcaaaca gctccaccgc accaaaggca
   102241 atccctaacg ccagcgccag caccgacagg gtaaacagct cgcgggaacc ggttgctgcg
   102301 ctacgtgcca taatccacgg caccagacgg cgacctacca gcatcataat ggcgataaat
   102361 gcgatcacct tgccgatggt gatccccata tcgacagcaa gagtggcaaa gcccacatcg
   102421 ccttgttcca tcattcctgc cactgcgggc agcaacacca gcgtcagaac catgaccagg
   102481 tcttccacaa tcaaccaacc gatggcgatt tgcccacgct gactgtcaat taattgccgt
   102541 tcttcaagtg cgcgcagtaa caccacggta ctggcggtgg aaaggcataa gccgaacacg
   102601 ataccggtca ttaacgacca gcccagcacg gcggagagcg ccatacccag cagcgtagcc
   102661 acggctatct gggcgatcgc gccgggaatg gcgatggcct ttaccgccat caaatccttg
   102721 agcgaaaagt gcaaaccgac gccaaacatc aacagaatga cgcccagttc agccagttcc
   102781 ggcgcaagct tggtatcggc aacaaagccc ggagtgaatg gtcctgccag cacacccgct
   102841 aacagatatc ccaccagagg agaaatacgt agtttattgg ccagcatgcc gaggataaag
   102901 gcgagcacaa ggccgccaac aatggtggtg ataagcgggg tggcgtgatg cattccgtct
   102961 ccttttcctg gtggttattg tccatttttg gccgggaaaa ccaaaattac aggtaatagt
   103021 ttatgacaat ttcattgatg atgtttatga ataattgttg aattttgcag aaaaatggaa
   103081 ttagctgcaa aaaaagcacg gatcggaaaa cagaaggcgg tttaacagag gaaaggctta
   103141 tggcgactgt aaaacgatgc agccaaagtt tgcctttggc tgcaatgaaa tcagtcttta
   103201 tgccggttat caggcaggaa tatggtcaac atccccaata gtggcaggaa agcacagatt
   103261 ttatagacta actcgatgct ggtgtgatcg gcgataagcc ccagaactgc cgctcccaga
   103321 cctcccatgc caaaagcaaa accgaaaaag aatccagaaa ccataccgat acgtcccgga
   103381 agtagctcct gagcgtagac cagaatggca gagaatgccg aagcgaggat aaatccaata
   103441 atcaccgtta aaacccccgt ccagtgcagg ctggcgtagg gtaaaatcag cgtaaacggc
   103501 gcaacgccga ggatagagcc ccaaatcaca tatttccgtc caattttatc ccctacaggc
   103561 ccgccgatca ccgtacctgc cgcaacggca aacaggaagg caaacagatg aagctgggca
   103621 ttctggatag ataatccgaa tttttgcatc agataaaagg tgtaatagct gctgatgctc
   103681 gccatataga aatatttcga gaaaatgagg attaacagaa tgctgaccgc cagtaccact
   103741 ttgttgcgcg gcagtggatt gataatcgtc gctttgggtt ttcctttatt cattcggtgc
   103801 tgtgccgagt accaacggct gatttgcgcc agcaccacga tcgccagcag tgccgcaagc
   103861 acaaaccagg caacgttgcc tttgccataa ggcgcgataa tcaccgccgc cagcaagggt
   103921 cccagggaac tgccaaagtt gccgccgacc tgaaagatag attgtgccag gccatgccgc
   103981 ccgccggacg ccatacgggc cacgcgagaa gattccggat gaaagaccga tgaaccggta
   104041 ccgaccagcg ccgccgccag cagaactgcg ccaaaactgc ccgccagcgc cagcagcacc
   104101 agaccactta aggtaaagca catgccaatt ggcaacgacc acggcatcgg atatttatcg
   104161 gtccagtagc cgacaactgg ttgcagtagc gaagaggcga gctggaaggt gagggttatc
   104221 atgccaatct gcataaatgt cagagaaaac tctgactgaa gcagcggata aatcgccaga
   104281 atcagcgatt ggatcatgtc gttcagcaga tgtgagaggc tgatagcacc taaaatacca
   104341 aacgatgttc gggccttggt cgttgacgca gccgcgcccg ccacaggctg ggtttgttca
   104401 ctcattgcca taggaaagtc actttttcag ggttgcgatg taaagaatga tcttatttgt
   104461 gattattacc cgactaacat acctgtatgc gccgcctgaa ggaagtctca acgctgaata
   104521 cagaatttct aatctggatg cagatttatc ttcaccggac gcagacttgt ctatgatgtc
   104581 gcgtcatact atttttcaac acgttgaaat caggtcaggg agagaagtat gaaattattg
   104641 cagcggggcg tggcgttagc actgttaacc acatttacac tggcgagtga aactgctctg
   104701 gcgtacgagc aggataaaac ctacaaaatt acagttctgc acaccaatga tcatcatggg
   104761 catttttggc gcaatgaata tggtgaatat ggtctggcgg cgcaaaaaac gctggtggat
   104821 ggtatccgca aagaggttgc ggctgaaggc ggtagcgtgc tgctactttc cggtggcgac
   104881 attaacactg gcgtgcccga gtccgactta caggatgccg aacctgattt tcgcggtatg
   104941 aatctggtgg gctatgacgc gatggcgatc ggtaatcatg aatttgataa cccgctcacc
   105001 gtattacgcc agcaggaaaa gtgggctaag ttcccgttgc tttccgccaa tatctaccag
   105061 aaaagtaccg gcgagcgcct gtttaaacca tgggcgctgt ttaagcgtca ggatctgaaa
   105121 attgccgtta ttggcctgac gacggatgac acagccaaaa ttggtaatcc ggaatatttc
   105181 actgatatcg aatttcgtaa gcccgctgat gaagcgaagc tggtgattca ggagctgcaa
   105241 cagacagaaa agccagacat tattatcgcg gcgacccata tggggcatta cgacaatggt
   105301 gagcacggct ctaacgcacc gggcgatgtg gagatggcac gcgcgctgcc tgccggatcg
   105361 ctggcgatga tcgtcggtgg tcactcgcaa gatccggtct gtatggcggc agaaaacaaa
   105421 aaacaggtcg attacgtgcc gggtacgcca tgcaaaccgg atcaacaaaa cggcatctgg
   105481 attgtgcagg cgcatgagtg gggcaaatac gtgggacggg ctgattttga gtttcgtaat
   105541 ggcgaaatga aaatggttaa ctaccagctg attccggtga acctgaagaa gaaagtgacc
   105601 tgggaagacg ggaaaagcga gcgcgtgctg tacacccctg aaatcgctga aaaccagcaa
   105661 atgatctcgc tgttatcacc gttccagaac aaaggcaaag cgcagctgga agtgaaaata
   105721 ggcgaaacca atggtcgtct ggaaggcgat cgtgacaaag tgcgttttgt acagaccaat
   105781 atggggcggt tgattctggc agcacaaatg gatcgcactg gtgccgactt tgcggtgatg
   105841 agcggaggcg gaattcgtga ttctatcgaa gcaggtgata tcagctataa aaacgtactg
   105901 aaagtgcagc cattcggcaa tgtggtggtg tatgccgaca tgaccggtaa agaggtgatt
   105961 gattacttga ccgccgtcgc gcagatgaag ccagattcag gtgcctaccc gcaatttgcc
   106021 aacgttagct ttgtggcgaa agacggtaaa ctgaacgacc tgaaaatcaa aggcgaaccg
   106081 gtcgatccgg cgaaaactta ccgcatggcg acattaaact tcaatgccac cggcggggat
   106141 ggctatccgc gccttgataa caaaccgggc tatgtgaata ccggctttat tgatgccgaa
   106201 gtgctgaaag cgtatatcca gaaaagctcg ccgctggatg tgagtgttta tgaaccgaaa
   106261 ggtgaggtga gctggcagta atccgaaagt gccggatgtt cgcatccggc acaatgctta
   106321 atcgcgacgg gcgatatcag caaatttggc atcgagtatc tttgccaggt cgcttgccgc
   106381 cagttcgata tccagaccgc gcttgccgcc ggaaacataa atagtggcaa attcttgtgc
   106441 gggggtgtcg ataatcgttg gcagacgttt tttctgcccc agtgggctaa tccctccaac
   106501 cagatatccc gtcgaacgct gcgcgaccat cggatcggcc atctcaactt tcttggcacc
   106561 cagcgctttt gctacttttt taagatccag ttgacctgcg accggcgtaa cggccacggc
   106621 aaggtgtttc atatcaccgt tcactgcgac cagcagcgtt ttgtagacct gatccggatt
   106681 caaacctaat tttttgacga cttcatcgcc aaaattggtt tcagccggat cgtgctcgta
   106741 ggtgtggatt tgaaacgaaa tcttgttttt ttcgagtaat ttaactgcgg gtgtcatggt
   106801 aattttcctg ccttaaacaa aaaaacgaag caagcatacg cctgatggcg gtccaaaaaa
   106861 aagagtcatc ttgcctaaga gtattggcag gatggtgaga ttgagcgaca atcgagttac
   106921 accgtcgctt aaagtgacgg cataataata aaaaaatgaa attcctcttt gacgggccaa
   106981 tagcgatatt ggccattttt ttagcgcaac atctgcggca aattcccttc tccatacagg
   107041 tgtagtgcac caaccgcgac cacatatcgc cccggcggca tggcgcgtaa tttgtcccgc
   107101 caggcgagat ttcgctgatg catcagcaca tcgtacagcg actgactgaa cgtattaggc
   107161 agcgttattt cattattttg tggcggtgta ttcagccacc agctcatcat ttgttgcagc
   107221 aaccgtgcgt tggtgtgcca gtgggtcagc gtatcgtcca gcagcgccag tccgttgtca
   107281 gggagctgga gcaacatggc aatctggttt tctgcccctt ccagttcaat cacgggttta
   107341 tgttgttgct tcgccgcctg caatagctgg taatcgatac cgtattctgc ccgcagcccc
   107401 agtttttgtg cctgcgtcgc ctgaagaacc atcgcgattt gccacagcgg ttgggtagaa
   107461 aagagtgagg tagaaatgcc catctcctgg ctaatgtgct gcaggttttg taattgctcc
   107521 tcgctaatgc gctcttccag cgcctcgcag gcaggcaaat tagcaaaagg cgtatcgctg
   107581 gtggaaacat ccgcctcgac gatcagcgca tcggcgtttt tgagcttttt gagcaaacgg
   107641 gtgggcaggg gagccatatc gtggctaccc atatgaatac tgccgagcag atgaaaatgg
   107701 cgattgccgg gaagagagat atcgatagca ggccaggtgt aatgattacc gcgcagcgcg
   107761 gcccaaagcg tttttacccg atacaacaga tccatacgac ctccctttgt gaaatatcat
   107821 gctagcgcgc ggggagggat ggcgcaaatg gagttgattg tcgcacttgt gcacagtgct
   107881 tgtgtgcatt acaataatta aacaatggac aaggagatga gaatggaatg gctcaaaaga
   107941 ataatataag gagttttcgt gatgcctggc tggctgattt ttttgtccat tcaacgccac
   108001 atcgaaagat ccctgctgaa atccatacca cgttatcacg aaagttggac atcattaatg
   108061 ctgccacttc tcatcgggat ttacgctccc ctccggggaa ccgatacgaa gagttgtctg
   108121 ggaaattaca ggaatattcc tccattagag tgaataaaca gtaccgactg atatttaaat
   108181 gggttaatgg caaggccgaa gaattgtttt tagacccaca caactactaa aacatagctg
   108241 tcgtattgac gagaaaggta aaaccatgaa acaggcaaca agaaaaccga cgacacccgg
   108301 agatattctt ctctatgaat atctggaacc gctcgatttg aaaatcaatg agttagcaga
   108361 gttactgcat gttcatcgta atagcgtcag tgcactgatc aataataatc gtaaactcac
   108421 cactgaaatg gcattccgtc tggcgaaagt ttttgatacc acagtcgatt tttggctaaa
   108481 cctccaggcg gcagttgatc tttgggaagt tgaaaacaac atgcgtaccc aggaagaatt
   108541 gggacggatt gaaacagtgg ctgaatattt ggcacgccgt gaagagcgtg caaaaaaggt
   108601 cgcgtagaat aatttcccta taacggatgc gccaccctaa agcagtgcat ccgtaatgat
   108661 gtacttattc cttcggttta aatcgcagca atcggttggc gttactcact acggtaatcg
   108721 acgagagcgc cattgccgct ccggcaacca ccgggttaag cagcgtaccg gtgaacggcc
   108781 acaaaatacc ggcggcgacc ggaataccaa tgctgttgta gataaacgca ccgagcaggt
   108841 tctgcttcat attgcgcagc gttgcgcggg aaatcgcgag cgcatctgca acacccatca
   108901 ggctatggcg catcagggta atcgccgcgg tttcaatggc aacatcactg ccgccaccca
   108961 tcgcaatacc gacatccgcc tgagccagcg ctggcgcgtc gttaatgccg tcgcccacca
   109021 ttgccacctg acgtccttca ctttgcagac gtttgatcgc ttcggcttta ccgtccggta
   109081 gcaccccggc tatcacctca tcaatccctg cttctttggc gatcgcattg gcggtggttg
   109141 ggttatcccc ggttagcatc accagacgat atcccgcttt atgcaggcgt tgcagcgccg
   109201 ccacgctatc actacgcaac ggatcgcgta cagccagcag ggctaccgct ttcccgtcaa
   109261 ccgccagcag cacaggcgtt gccccttgcg atgcctgagc tgaaatatct gcctcaatcg
   109321 ctttagtatc aacttgctgg tcatttaaca gcgcctgatt acccagcaat aacgcatgac
   109381 cttcagcttc accgctcacg cccagcccgc gcaatgtgcg gaaaccgttg acctgcggca
   109441 gctgcatatc acctgcttta tcgaggatcg ctcgtgccag cggatggctg gaaccttgct
   109501 ccagtgccgc cgccagacgc aatgcctgcg cttcatcaac atcagcaaac gttttcactg
   109561 cgacaacctg cggcttccct tcggtcagcg tcccggtttt atcgaacacg acggtgtcga
   109621 gcgtactggc gcgttgcagc gcgtcagcgt cccgcaccag cacgccaaac tcagccgccc
   109681 gcccgacgcc cgaaataatc gacatcggcg tcgccagtcc cagcgcacac ggacaggcaa
   109741 taatcagcac cgtggtggca atcaccaggg tatagacaat ttgcggtgcc ggaccaaaga
   109801 aataccagat tgccgcactg acaagcgcaa taaccactac taccggcaca aatacggctg
   109861 agattttatc cgccagttga ccgatttctg gcttgctgct ctgggcctgt cgcaccatgc
   109921 gaatgatccg tgacagcgta gtatggctgc cgaccgcact ggcgcgaaac agcacactgc
   109981 cgtcctgtac cactgtcccg gcatggacgc tatcgccttc gcctttttgc tgcgggattg
   110041 gttcgcccgt cagcatcgct tcatccagcc acgcttcgcc ctgggtaatt tcaccatcta
   110101 ccggcacccg atcacccgtc gtcaggcgca gcaacatacc tggctgaaca tctgccagcg
   110161 gcacgttttt ttcaccttcg ttggtgacca ggcgcgccgt cggtggggtt aaatcgagta
   110221 atttctccag cgccttagaa gaacactgac gtgcgcgcgc ttccagcata tgaccgagat
   110281 taatcagacc gataatcatc gcactggctt catagtaaag atgtcgcgct tccatcggga
   110341 accactgcgg ccacaggttg acgctcattg aatagagcca cgccacgccc gtacccagcg
   110401 ccaccagcgt atccatcgtc gctgcaccgt tcagcaggct tttccatgcg ctgcggtaaa
   110461 aatggccgcc ggcgaaaacc attaccgcca gggttatcag gccgataacc aaccacaggc
   110521 tgcggttgtc ggcggtgacc atcatgttat cgccgatcat cccccagacc atcaccggga
   110581 tacccaccgc cagtgcgaca atcgcctgcc agcggaagcg cttcatcgta gcgacggcgg
   110641 tttcttgctg gcgctcgcgg cgtttagcgt catcttcaat cgcttccgcg ccgtagcccg
   110701 ctttttccac cgcctgcact aaatcttgtg gggaggcact gcccatcacc agcgcagtac
   110761 gctccgccag gtttacccgt gcctgagtga cgcccggtac gctttgcaac gcattttgta
   110821 cgcgggtgac acagctggcg cagctcatgc cgctcagcag caactgctgg ctgtcatcgt
   110881 catcggcggt cgctgccgga agcgcctcag aaaccgctgt cagtgcttcc gacgggattg
   110941 atgactccgc cagcggttta gcctttgggt ggcttacaga tgcgtcataa cccgcttgtt
   111001 tgatggtttc gatcagctgt tctgcactgg cagtcccggt aacgtgcgct tcagtgacag
   111061 acacatccgc ctgctcaaca tccgggcgct gttcgagact ttctttcacg cgtttaacgc
   111121 agtgaccgca ggacaggccg tccagggtca ggtcgatagt ttgtgacata aaacactcct
   111181 tttaagacag ttttgactgg ctgtgataaa ggttaaacct tccagcaagg ggaaggtcaa
   111241 gaaattaata aaccaggcgg gtaaaagtac gtaaagatta aaaaatcggc tcgatttgca
   111301 tcaggattag acatttatct ctttgttttc ctgtagttaa gttgcgggtg ctaagttaaa
   111361 tcaggatgcc tgaaaattgg caccggggtg aggaattacc tcccgcatct ataaaaagga
   111421 gttaacaaaa gatgttagat gcaaacaaat tacagcaggc agtggatcag gcttacaccc
   111481 aatttcactc acttaacggc ggacaaaatg ccgactacat tccctttctg gcgaatgtac
   111541 ctggtcaact ggcagcagtg gctattgtga cctgcgatgg caacatctat cgcgcgggtg
   111601 atagtgatta ccgctttgcg ctggaatcca tctcgaaagt ctgtacgtta gcccttgcgt
   111661 tagaagatgt cggcccgcag gcggtacagg acaaaattgg cgctgacccg accggattgc
   111721 cctttaactc agttatcgcc ttagagttgc atggcggcaa accgctgtcg ccactggtaa
   111781 atgctggcgc tattgccacc accagcctga ttaacgctga aaatactgaa caacgctggc
   111841 agcgaatttt acatatccaa caacaactgg ctggtgagca ggtagcgctc tctgacgaag
   111901 tcaaccagtc ggaacaaaca accaacttcc ataaccgggc cattgcctgg ctgctgtact
   111961 ccgccggata tctctattgt gatgcaatgg aagcctgtga cgtgtacacc cgtcagtgct
   112021 ccacgctcat caatactgtt gaactggcaa cgcttggcgc gacgctggcg gcgggtggtg
   112081 tgaatccgct gacgcataaa cgcgttcttc aggccgacaa cgtgccgtac attctggctg
   112141 aaatgatgat ggaagggctg tatggtcgct ccggtgactg ggcgtatcgc gttggtttac
   112201 cgggcaaaag cggtgtaggt ggcggtattc tggcggtcgt ccctggcgtg atgggaattg
   112261 ccgcgttctc accaccgctg gacgaagaag gcaacagtgt tcgcggtcaa aaaatggtgg
   112321 catcggtcgc taatcaactc ggctataacg tgtttaaggg ctgatcatga tgaacacgga
   112381 aggtaataac gataacaaac ccctcggtct atggaacgtc gtttccatcg gtattggggc
   112441 aatggtgggg gcggggatct tcgcgctgct ggggcaggct gcgttgctaa tggaagcctc
   112501 gacctgggtc gcctttgctt ttggcggtat tgtggcgatg ttttccggtt atgcctatgc
   112561 gcgcctgggg gcgagctatc ccagcaatgg cggtattatc gacttctttc gtcgcggatt
   112621 aggcaacggc gtcttttcgc tggcactctc gttattgtac ctgttgacgc tggcggtgag
   112681 catcgccatg gtcgcccgtg cttttggcgc ttatgccgtg cagtttttgc atgaaggcag
   112741 tcaggaggag caccttatat tgctctacgc gttggggatc attgcggtga tgacgctttt
   112801 caactcctta agcaaccatg cggtagggcg gctggaagtg atcctcgtcg gcattaaaat
   112861 gatgatcctg ttattgctga tcattgccgg tgtctggtcg ctgcaaccgg cgcatatttc
   112921 cgtctctgcg ccccccagct ccggtgcgtt cttctcctgt atcgggataa ccttccttgc
   112981 ctatgcgggc tttggcatga tggcgaacgc ggcggataaa gtgaaagatc cgcaggtcat
   113041 tatgccacgg gcgtttctgg tggcgattgg cgttaccacg ttgctttata tctcgctggc
   113101 gctggttttg cttagcgatg tatcggcatt agagttagaa aaatatgccg ataccgccgt
   113161 agcgcaggca gcttctccgc tgctcgggca tgtgggttat gtgatcgtcg tcatcggcgc
   113221 tttactggcg acggcttcag ccatcaacgc gaacctgttc gccgtgttta acatcatgga
   113281 caacatgggc agcgaacgcg aactgccgaa gctaatgaat aaatccctgt ggcggcagag
   113341 tacctggggc aacatcattg tcgtggtgct gattatgctg atgacggcgg cgctgaattt
   113401 aggctcactc gccagcgttg ccagcaccac ctttttgatc tgctatctgg cggtgtttgt
   113461 ggtggcgatc cgcctacgtc atgatattca cgcctcgttg ccgattctta tcgttggtac
   113521 gttggtgatg ttgttggtga tcgttggctt tatctacagc ctgtggtccc agggcagccg
   113581 tgcgttgata tggattattg gtgcaatctt actcagcctt attgtggcaa tggtcatgaa
   113641 gcgcaataaa accgtataac atctctctgt gcgcagtact tcctgtatta ttgtggtggc
   113701 ggtcgatatt cgcactggca aaaaaacgtg cttgaatatt tgttgaaacc ctttaacaaa
   113761 gcacaggagg cgttgcgcga acgatgaaca ttagcgatgt agcaaaaatt accggcctga
   113821 ccagcaaagc cattcgcttc tatgaagaga aggggctggt gacgccgccg atgcgcagcg
   113881 aaaacggtta tcgcacctac acgcagcagc atctcaacga actgacctta ctgcgccagg
   113941 cacgccaggt gggctttaac ctggaggaga gcggcgaact ggtgaatctg tttaacgatc
   114001 cgcagcgtca tagtgccgac gtcaaacgtc gtacgctgga gaaggtggcg gagatcgaac
   114061 ggcatatcga agaactgcaa tccatgcgca accagctact ggcgctggcg aatgcctgcc
   114121 ctggcgatga cagcgccgac tgcccgatta tcgaaaatct ctccggctgc tgtcatcatc
   114181 gggcggggtg aaaatcagtt aatccccgtt tgcaccgaaa gaatatgctg caaactttct
   114241 accattatgc gccccgactg aaataagcct tcctggattt cgttgttaac attcacagcg
   114301 tgaaccaggg aggctaataa caccacttgc aagaaggcaa aaataaacgc accgataatc
   114361 ataatatgcg tcagggggat tttcctttgc tccttcattt taaataaccc acaaactgac
   114421 cttccttcat taaggcgact tttcccgtat ggtgataaac aatgacgtta taaagacctg
   114481 actgataaac agtggcatct ttattgtctt catcaattgc acataatgaa tcattgagat
   114541 aagcaaagtt cttactgctc attctaaagg tcatgccaaa tcctttataa atggctttct
   114601 ttgccgcctg ggcatgttgt gcggcttctg catttttaaa tgcctgcgcc tcggatgcac
   114661 ttaaaatagc cgtctgacgc tgttgttctg cgagataaca ggtgtcatgg ctgacgccct
   114721 gcgcctggca atctgcgatg cgggaagtgg gtgaactaca gccagtcagt aatataaccg
   114781 ccagcaggga aaacgattta atggagctat tcatcattgt taaccttaaa taatgtacaa
   114841 attaatgaag aggtgaaccc ggcaagcttc cttgctctta tttatattga ggattgaaat
   114901 attagaacga atatcccacg ccgacacctg cgccgaaatc agattgtgta tccgcagaaa
   114961 taccggcttt aagtaccgta tgcgttccgg cattaaaaga tgttcctaca gacaccgcag
   115021 attcaccgtt gaaggttccc gctcccgctg acaccatcat cacgtcaccg gttttcacct
   115081 gtggttgtga ggcgatagcg atggcagatg cagttcccgc attggcttct ttacgattgt
   115141 cctcaacttc gtttttcaga gaatcgaaat ggttattgag cgtgttaatt tgctggctgt
   115201 tatctgcaac ccgtttttgg gtgttggtta actgttgctg cgtttgtgcg gaatcttgtc
   115261 tcagactttc aatttgctca tgtgcctgga cagacttctg cgccagactt tgcatttgtt
   115321 tatcgtattg agccctttct ttttgctgtt gtgctgccac atcggttgtc agtgcattca
   115381 ttttctgccc ttgttccgtg gtagtgcgct gattagcctc attttgagcc gccagtctgg
   115441 cattaatcat ctcctgataa tgcgcagtat tttgcgtatc tccagtcgcg gcgagcgttt
   115501 tttgtgtggc tacgatctgc gcctgttgct ctgtaatttg cgtttgctgg gcatcagtta
   115561 ccgcagactg tcgggcgttg atcatgctct gataacgggc aggtgtctgt gcatcacctg
   115621 tagcggcaac ggttttttgt cctgcgtcag gatctgtctg gacagtggga gtctgagtgg
   115681 tatcaggtgt ttcagaaggg atgtagtgat gttcagtcaa ataggtatac gcagcggggc
   115741 tgttgtctgt gcgttctaaa aagcgggtaa tcttctgctc aatctccgat tgcgacatgc
   115801 cagagttaat ggctgaaagc tctgttgccg ccgcttcaat ggtatcacca gctaaaacaa
   115861 cagggctgga tgttgctgaa attatgagtg ccagtaaagc tacgtttaca gttttcattc
   115921 attttctctt gttcaaaata agttgcatta atgtttctat aagaaacaaa taatattatt
   115981 ttaagaaata aactgcgttg caatttaatc gaaatctacg ccgccatttg tgtgatgtaa
   116041 agcgcatttt tgtctggt
//
LOCUS       DADXDL010000004       113758 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.004, whole genome shotgun sequence.
ACCESSION   DADXDL010000004 DADXDL010000000
VERSION     DADXDL010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 113758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 113758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..113758
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.004"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            49..972
                     /locus_tag="IRB70_000331"
     CDS             49..972
                     /locus_tag="IRB70_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310054.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0630290.1"
                     /translation="MEKNSLFSQRIRLRHLHTFVAVAQQGTLGRAAETLNLSQPALSK
                     TLNELEQLTGARLFERGRQGAQLTLPGEQFLTHAVRVLDAINTAGQSLHRKEGLNNDV
                     VRVGALPTAALGILPSVIGQFHQQQKETTLQVATMSNPMILAGLKTGEIDIGIGRMSD
                     PELMTGLNYELLFLESLKLVVRPNHPLLQENVTLSRVLEWPVVVSPEGTAPRQHSDAL
                     VQSQGCKIPSGCIETLSASLSRQLTVEYDYVWFVPSGAVKDDLRHATLVALPVPGHGA
                     GEPIGILTRVDATFSSGCQLMINAIRKSMPF"
     gene            complement(1011..2651)
                     /gene="trg"
                     /locus_tag="IRB70_000332"
     CDS             complement(1011..2651)
                     /gene="trg"
                     /locus_tag="IRB70_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein Trg"
                     /protein_id="HBC0630291.1"
                     /translation="MNTTPSQRLGFLHHIRLVPLFACILGGILVLLALSSALAGYFLW
                     QADRDQRDVTAEIEIRTGLANSSDFLRSARINMIQAGAASRIAEMEAMKRNIAQAESE
                     IKQSQQGYRAYQNRSVKTPADEALDTELNQRFQAYITGMQPMLKYAKNGMFEAIINHE
                     SEQIRPLDNAYTDILNKAVKIRSTRANQLAELAHQRTRLGGMFMIGAFVLALVMTLIT
                     FIVLRRIVIRPLQHAAQRIEKIASGDLTMNDEPAGRNEIGRLSRHLQQMQHSLGMTVG
                     TVRQGAEEIYRGTSEISAGNADLSSRTEEQAAAIEQTAASMEQLTATVKQNADNAHHA
                     SKLAQEASIKASDGGQTVSGVVKTMGAISTSSKKISEITAVINSIAFQTNILALNAAV
                     EAARAGEQGRGFAVVASEVRTLASRSAQAAKEIEGLISESVRLIDLGSDEVATAGKTM
                     STIVDAVASVTHIMQEIAAASDEQSRGITQVSQAISEMDKVTQQNASLVEEASAAAVS
                     LEEQAARLTEAVDVFRLNKHSVSAEPRGAGESVSFATV"
     gene            3026..3175
                     /gene="hokB"
                     /locus_tag="IRB70_000333"
     CDS             3026..3175
                     /gene="hokB"
                     /locus_tag="IRB70_000333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokB"
                     /protein_id="HBC0630292.1"
                     /translation="MKRNPLVVCLLIICITILTFTLLTRQTLYELRFRDGDKEVAALM
                     ACTSR"
     gene            complement(3247..3420)
                     /locus_tag="IRB70_000334"
     CDS             complement(3247..3420)
                     /locus_tag="IRB70_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630293.1"
                     /translation="MKKLALILVLGALVSFYADAGRKPCSGSKGGISHCTAGGKFVCN
                     DGSISASKKTCTN"
     gene            complement(3665..4195)
                     /gene="cybB"
                     /locus_tag="IRB70_000335"
     CDS             complement(3665..4195)
                     /gene="cybB"
                     /locus_tag="IRB70_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415935.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b561"
                     /protein_id="HBC0630294.1"
                     /translation="MGNKYSRLQISIHWLVFLLVIVAYCAMEFRGFFPRSDRPLINMI
                     HVSCGISILVLMVVRLLLRLKYPTPPIIPKPKPMMTGLAHLGHLVIYLLFIALPVIGL
                     VMMYNRGNPWFAFGMTMPYASEANFERVDSLKSWHETLANLGYFVIGLHAAAALAHHY
                     FWKDNTLLRMMPRKRS"
     gene            4384..5384
                     /gene="gap"
                     /locus_tag="IRB70_000336"
                     /pseudo
     CDS             4384..5384
                     /gene="gap"
                     /locus_tag="IRB70_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310049.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
     gene            complement(5425..6864)
                     /gene="aldA"
                     /locus_tag="IRB70_000337"
     CDS             complement(5425..6864)
                     /gene="aldA"
                     /locus_tag="IRB70_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBC0630295.1"
                     /translation="MSVPVQHPMYIDGQFVTWRGDAWIDVVNPATEAVISRIPDGQAE
                     DARKAIDAAERAQPEWEALPAIERASWLRKISAGIRERASEISALIVEEGGKIQRLAE
                     VEVAFTADYIDYMSEWARRYEGEIIQSDRPGENILLFKRALGVTTGILPWNFPFFLIA
                     RKMAPALLTGNTIVIKPSEFTPNNAIAFAKIVDEIGLPRGVFNLVLGRGETVGQELAG
                     NPKVAMVSMTGSVSAGEKIMATAAKNITKVCLELGGKAPAIVMDDADLELAVKAIVDS
                     RVINSGQVCNCAERVYVQKGIYDQFVNRLGEAMQAVQFGNPAERNDIAMGPLINAAAL
                     ERVEQKVARAVEEGARVALGGKAVEGKGYYYPPTLLLDVRQEMSIMHEETFGPVLPVV
                     AFDTLEEAISMANDSDYGLTSSIYTQNLNVAMKAIKGLKFGETYINRENFEAMQGFHA
                     GWRKSGIGGADGKHGLHEYLQTQVVYLQS"
     gene            complement(7061..7861)
                     /locus_tag="IRB70_000338"
     CDS             complement(7061..7861)
                     /locus_tag="IRB70_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBC0630296.1"
                     /translation="MNITPFPTLSPATIDAINVIGQWLAQDDFSGEVPYQADCVILAG
                     NAVMPTIDAACKIARDQQIPLLISGGIGHSTTFLYSAIAQHPHYNTIRTTGRAEATIL
                     ADIAHQFWHIPHEKIWIEDQSTNCGENARFSIALLNQAVERVHTAIVVQDPTMQRRTM
                     ATFRRMTGDNPDAPRWLSYPGFVPQLGNNADSVIFINQLQGLWPVERYLSLLTGELPR
                     LHDDSDGYGPRGRDFIVHVDFPAEVIQAWQTLKHDAVLIEAMESRSLR"
     gene            complement(8134..12036)
                     /gene="hrpA"
                     /locus_tag="IRB70_000339"
     CDS             complement(8134..12036)
                     /gene="hrpA"
                     /locus_tag="IRB70_000339"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase HrpA"
                     /protein_id="HBC0630297.1"
                     /translation="MTEQQKLTFTALQQRLDSLMLRDRLRFSRRLHGVKKVKNPDAQQ
                     AIFQEMAKEIDQAAGKVLLREAARPEITYPDNLPVSQKKQDILEAIRDHQVVIVAGET
                     GSGKTTQLPKICMELGRGIKGLIGHTQPRRLAARTVANRIAEELKTEPGGCIGYKVRF
                     SDHVSDNTMVKLMTDGILLAEIQQDRLLMQYDTIIIDEAHERSLNIDFLLGYLKELLP
                     RRPDLKIIITSATIDPERFSRHFNNAPIIEVSGRTYPVEVRYRPIVEEADDTERDQLQ
                     AIFDAVDELSQESPGDILIFMSGEREIRDTADALNKLNLRHTEILPLYARLSNSEQNR
                     VFQSHSGRRIVLATNVAETSLTVPGIKYVIDPGTARISRYSYRTKVQRLPIEPISQAS
                     ANQRKGRCGRVSEGICIRLYSEDDFLSRPEFTDPEILRTNLASVILQMTALGLGDIAA
                     FPFVEAPDKRNIQDGVRLLEELGAITTDEQASAYKLTPLGRQLSQLPVDPRLARMVLE
                     AQKHGCVREAMIITSALSIQDPRERPMDKQQASDEKHRRFHDKESDFLAFVNLWNYLG
                     EQQKALSSNAFRRLCRTDYLNYLRVREWQDIYTQLRQVVKELGIPVNSEPAEYREIHI
                     ALLTGLLSHIGMKDADKQEYTGARNARFSIFPGSGLFKKPPKWVMVAELVETSRLWGR
                     IAARIDPEWVEPVAQHLIKRTYSEPHWERAQGAVMATEKVTVYGLPIVAARKVNYSQI
                     DPALCRELFIRHALVEGDWQTRHAFFRENLKLRAEVEELEHKSRRRDILVDDETLFEF
                     YDQRISHDVISARHFDSWWKKVSRETPDLLNFEKSMLIKEGAEKISKLDYPNFWHQGN
                     LKLRLSYQFEPGADADGVTVHIPLPLLNQVEESGFEWQIPGLRRELVIALIKSLPKPV
                     RRNFVPAPNYAEAFLGRVTPLELPLLDSLERELRRMTGVTVDREDWHWDQVPDHLKIT
                     FRVVDEKNKKLKEGRSLQDLKDALKGKVQETLSAVADDGIEQSGLHIWSFGQLPESYE
                     QKRGNYKVKAWPALVDERDSVAIKLFDNPLEQKQAMWNGLRRLLLLNIPSPIKYLHEK
                     LPNKAKLGLYFNPYGKVLELIDDCISCGVDQLIDANGGPVWTEEGFAALHEKVRAELN
                     DTVVDIAKQVEQILTAVFNINKRLKGRVDMTMALGLSDIKAQMGGLVYRGFVTGNGFK
                     RLGDTLRYLQAIEKRLEKLAVDPHRDRAQMLKVENVQQAWQQWINKLPPARREDEDVK
                     EIRWMIEELRVSYFAQQLGTPYPISDKRILQAMEQISG"
     gene            12237..12842
                     /gene="azoR"
                     /locus_tag="IRB70_000340"
     CDS             12237..12842
                     /gene="azoR"
                     /locus_tag="IRB70_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBC0630298.1"
                     /translation="MSKVLVLKSSILAGYSQSNQLSDYFVEQWREKHSADEITVRDLA
                     ANPIPVLDGELVGALRPSDAPLTPRQQEALALSDELIAELKSHDVIVIAAPMYNFNIS
                     TQLKNYFDLVARAGVTFRYTENGPEGLVTGKKAIVITSRGGIHKDGPTDLVTPYLSTF
                     LGFIGITDVKFVFAEGIAYGPEMAAKAQSDAKAAIDSIVAA"
     gene            complement(12896..14212)
                     /locus_tag="IRB70_000341"
     CDS             complement(12896..14212)
                     /locus_tag="IRB70_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310040.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2/dual specificity phosphatase
                     family protein"
                     /protein_id="HBC0630299.1"
                     /translation="MITERRNVLLQGAGWLLLLAPFFFFTYGFLNQFTATQDLNNHDI
                     PSQVFGWETAIPFLPWTIVPYWSLDLIYGFSLFICSSTFEQRRLVHRLILATVMACCG
                     FFLYPLKFSFIRPEVSGVTGWLFSQLELFDLPYNQSPSLHIILCWLLWRHFRQHLAVR
                     WRKVCGGWFLLIAISTLTTWQHHFIDVITGLAVGMLIDWMVPVDRRWNYQKPDQRRIK
                     IALPYVVGACSCIVLMELMIMLQLWWSVWLCWPVLSLFIIGRGYGGLGAITTGKDSQG
                     KLPPAVYWLTLPWRIGMWLSMRWFCLRLEPVSKITAGVYLGAFPRHIPAQNAVLDVTF
                     EFPRGRATKDQLYFCVPMLDLVVPEEGELRQAVAMLETLREEQGGVLVHCALGLSRSA
                     LVVAAWLLCYGHCKTVDEAISYIRARRSRIVLKEEHKAMLKLWENR"
     gene            complement(14202..15959)
                     /locus_tag="IRB70_000342"
     CDS             complement(14202..15959)
                     /locus_tag="IRB70_000342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional alpha/beta hydrolase/class I
                     SAM-dependent methyltransferase"
                     /protein_id="HBC0630300.1"
                     /translation="MENSRIPGEHFFTTSDNTALFYRHWPTLQPGAKKVIVLFHRGHE
                     HSGRLQHIVDELTMPDTAFYAWDARGHGKTSGPRGYSPSLARSVQDVDEFVRFAASDS
                     QVGLEEVVVIAQSVGAVLVATWVHDYAPAIRGLVLASPAFKVKLYVPLARPALALWHR
                     LRGLFFINSYVKGRYLTHDRQRVASFNNDPLITRAIAVNILLDLYKTSERIVSDAAAI
                     TLPTQLLISGDDYVVHRQPQIDFYQRLRSPLKELHLLPGFYHDTLGEENRAQAFEKMQ
                     SFISRLYANKSQKFDYQHEDRTGPSADRWRLLSGGPVPLSPVDLAYRFMRKAMKLFGT
                     HSAGLHLGMSTGFDSGSSLDYVYQNQPQGSNAFGRLIDKIYLNSVGWRGIRQRKTHLQ
                     ILIKQAVADLHAKGLAVRVVDIAAGHGRYVLDALANEPAVSDILLRDYSELNVAQGQE
                     MIAQRGMSGRVRFEQGDAFNPEELSALTPRPTLAIVSGLYELFPENEQVKNSLAGLAN
                     AIEPGGILIYTGQPWHPQLELIAGVLTSHKDGKPWVMRVRSQGEMDSLVHDAGFDKCT
                     QRIDEWGIFTVSMAVRRDN"
     gene            complement(15975..16871)
                     /locus_tag="IRB70_000343"
     CDS             complement(15975..16871)
                     /locus_tag="IRB70_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBC0630301.1"
                     /translation="MMEKSLATLFALLILATLINRFRVWRLPERKGDEVTLRIRTWWG
                     IVICFSLVISGPRWMTLTFFALISFLALKEYCTLISVHFPRWLYWGIPLNYLLIGHNC
                     FELFLLFIPLAGFLILATWQVFVGDPSGFLHTVSAIFWGWIMTVFALSHAAWLLMLPT
                     INIQGEALLVLFLLALTESNDIAQYLWGKSCGRRKVVPKVSPGKTLEGLVGGVITTMI
                     ASLIIGPLLTPLNTLQALLAGLLIGISGFCGDVVMSAIKRDIGVKDSGKLLPGHGGLL
                     DRIDSLIFTAPVFFYFIRYCCY"
     gene            complement(16871..17476)
                     /locus_tag="IRB70_000344"
     CDS             complement(16871..17476)
                     /locus_tag="IRB70_000344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBC0630302.1"
                     /translation="MTLYQIKPLFQSLLRPTMFWLYKHHVTANHITLAALALSLLTGL
                     LLMLVAQPILFLLLPIVLFIRMALNALDGMLARECNQQTRLGEILNETGDVISDIALY
                     LPFLFLPESNPSLVILMLFCTILTEFCGLLAQTINGIRSFAGPFGKSDRALIFGLWGL
                     AVAIYPQWMQWNNLLWGIASILLIWTAINRCRSVLLMSAER"
     gene            complement(17647..19953)
                     /locus_tag="IRB70_000345"
     CDS             complement(17647..19953)
                     /locus_tag="IRB70_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310036.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2773 domain-containing bactofilin"
                     /protein_id="HBC0630303.1"
                     /translation="MFKPRICSWIGLLPLFMLSLPVQADLRCVANAVDIEPFFSAATA
                     EDKQQVEQAINSSVNLVPFGLSASDWKVHRGDLVVDGNIESNQKLIVLGNLTVKGNIS
                     TFSLSNPWVILGNVTATNIVTDSPLLITGSINASGLVFIDSYYDNPSTIKGSINARGI
                     FINDIIAPVVASSTNSEFMVRASDKNDTENVKKALMIINPDAYYWDLINDEDALKEIF
                     KRSNIRMAGNVCNLMKKEALFRPKPSPELVQELQMLDEGNVAAFEGRDIATFDLAIMR
                     TLPRLKGISANLRKQLINSNDGQTIESMARYMPDNEILELTDQQLGYQPVVLGLLDRE
                     PLSVEIMTRMSHLPDGVGPLNLALRENLPLDIVMTLAKRDWDMIIQELYKDAWLLPES
                     IIDGYIRSDDSSIRQVGAGGQLTYNQAMQLANDSSNDVVTSLASKLAEMKHHGQLLRM
                     TPQESDKIAVYLYQKFENDDDLIGALFLALPDNLQFNFVKRMEKKSPAYFCCRDMQVI
                     HSDAALQRLLTRFNDPEGWSNLAKNQYLSTAMKQKIWHRALSHRKNNPKADSAAYETS
                     ADMILSELISYGEVDDQMLLNAASLIRSEGWDFLESALVSWDNLPAVVLKELQQNMPR
                     NDIWAKFFLRQENSSRAQVNEALRVYYALDPDALAQLDVLAKQPDRIWWSSLAKSNLT
                     FFKFGALNNRHTPSAALAAEIDPEWWIVAMNNPRFPVDVLKARLKRDPLLALELVKPE
                     LDLVRQLALNGKTRAIREQAMRKLDELY"
     gene            complement(20017..20877)
                     /gene="pdxI"
                     /locus_tag="IRB70_000346"
     CDS             complement(20017..20877)
                     /gene="pdxI"
                     /locus_tag="IRB70_000346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine 4-dehydrogenase"
                     /protein_id="HBC0630304.1"
                     /translation="MSSNTFTLGTKSVNRLGYGAMQLAGPGVFGPPRDRHVAITVLRE
                     ALALGVNHIDTSDFYGPHVTNQIIREALYPYSDDLTIVTKIGARRGEDASWLPAFSPA
                     ELQKAVHDNLRNLGLDVLDVVNLRVMMGDGHGPAEGSIEASLTVLAEMQEQGLVKHIG
                     LSNVTPTQVAEARKITEIVCVQNEYNIAHRADDAMIDALARDGIAYVPFFPLGGFTPL
                     QSSTLSDVAASLGATPMQVALAWLLQRSPNILLIPGTSSVAHLRENMAAEKLHLSEEV
                     LSTLDGISRE"
     gene            complement(21108..21698)
                     /gene="paaY"
                     /locus_tag="IRB70_000347"
     CDS             complement(21108..21698)
                     /gene="paaY"
                     /locus_tag="IRB70_000347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaY"
                     /protein_id="HBC0630305.1"
                     /translation="MPIYQIDGLTPVVPEESFVHPTAVLIGDVILGKGVYVGPNASLR
                     GDFGRIVVKDSANIQDNCVMHGFPEQDTVVEEDGHIGHSAILHGCIIRRNALVGMNAV
                     VIDGAVIGENSIVGASAFVKAKAEMPANYLIVGSPAKAIRELSEQELAWKKQGTHEYQ
                     VLVTRCKQTLHQVEPLREVEPGRQRLVFDENLRPKQ"
     gene            complement(21680..21862)
                     /locus_tag="IRB70_000348"
     CDS             complement(21680..21862)
                     /locus_tag="IRB70_000348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001340141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylacetic acid degradation protein PaaX"
                     /protein_id="HBC0630306.1"
                     /translation="MRDYQTFIGKLYQRVAPAALAFVSEKGETSVGELPAPGSLYFQR
                     FGGLNIEQEALCQFIR"
     gene            21827..22039
                     /locus_tag="IRB70_000349"
     CDS             21827..22039
                     /locus_tag="IRB70_000349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005154028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0630307.1"
                     /translation="MKFADKGLVVAQYIRNRRLDFCADAIRHAADDEKLAGIGFHWGF
                     SDQSHFSTVFKQRFGMTPGEYRRKFR"
     gene            complement(22210..22536)
                     /locus_tag="IRB70_000350"
     CDS             complement(22210..22536)
                     /locus_tag="IRB70_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbL family protein"
                     /protein_id="HBC0630308.1"
                     /translation="MKKTLLLCAFLVGLVSSNVMALTLDEARTQGRVGETFYGYLVAL
                     KTDAETEKLVNDINAERKASYQQLAKQNNVSVDDIAKLAGQKLVARAKPGEYVQGING
                     KWVRKF"
     gene            complement(22544..22729)
                     /locus_tag="IRB70_000351"
     CDS             complement(22544..22729)
                     /locus_tag="IRB70_000351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnbE family lipoprotein"
                     /protein_id="HBC0630309.1"
                     /translation="MKILLAALTSSFMLVGCTPRIEVAAPKEPITINMNVKIEHEIII
                     KADKDVEELLETRSDLF"
     gene            complement(22726..25365)
                     /locus_tag="IRB70_000352"
     CDS             complement(22726..25365)
                     /locus_tag="IRB70_000352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbH family protein"
                     /protein_id="HBC0630310.1"
                     /translation="MLGKYKAVLALLLLIILVPLTLLMTLGLWVPTLAGIWLPLGTRI
                     ALDESPRITRKGLIIPDLRYLVGDCQLAHITNASLSHPSRWLLNVGTVELDSACLAKL
                     PQTEQSPAAPKTLAQWQAMLPNTWINIDKLIFSPWQEWQGKLSLALTSDIQQLRYQGE
                     KVKFQGQLKGQQLTVSELDVVAFENQPPVKLVGEFTMPLVPNGLPVSGHATATLNLPQ
                     EPSLVDAELDWQENSGQLIVLARDNGDPLLDLPWQITRQQLTVSDGRWSWPYAGFPLS
                     GRLGVKVDNWQAGLENALVSGRLSVLTQGQAGKGNAVLNFGPGKLSMDNSQLPMQLTG
                     EAKQADLILYARLPAQLSGSLTDPTLAFEPGALLRSKGRVIDSLDIDEIRWPLAGVKV
                     TQRGVDGRLQAILQAHENELGDFVLHMDGLANDFLPDAGRWQWRYWGKGSFTPMNATW
                     DVAGKGEWHDSTITLTDLSTGFDQLQYGTMTVEKPRLILDKPVVWVRDAQHPSFSGAL
                     SLDAGQTLFTGGSVLPPSTLKFSVDGRDPTYFLFKGDLHAGEIGPVRVNGRWDGIRLR
                     GNAWWPKQSLTVFQPLVPPDWKMNLRDGELYAQVAFSAAPEQGFRAGGHGVLKGGSAW
                     MPDNQVNGVDFVLPFRFADGAWHLGTRGPVTLRIAEVINLVTAKNITADLQGRYPWTE
                     EEPLLLTDVSVDVLGGNVLMKQLRMPQHDPALLRLNNLSSSELVSAVNPKQFAMSGAF
                     SGALPLWLNNEKWIVKDGWLANSGPMTLRLDKDTADAVVKDNMTAGSAINWLRYMEIS
                     RSSTKINLDNLGLLTMQANITGTSRVDGKSGTVNLNYHHEENIFTLWRSLRFGDNLQA
                     WLEQNARLPGNDCPQGKECEEKQ"
     gene            25573..26562
                     /gene="ldhA"
                     /locus_tag="IRB70_000353"
     CDS             25573..26562
                     /gene="ldhA"
                     /locus_tag="IRB70_000353"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HBC0630311.1"
                     /translation="MKLAVYSTKQYDKKYLQQVNESFGFELEFFDFLLTEKTAKTANG
                     CEAVCIFVNDDGSRPVLEELKKHGVKYIALRCAGFNNVDLDAAKELGLKVVRVPAYDP
                     EAVAEHAIGMMMTLNRRIHRAYQRTRDANFSLEGLTGFTMYGKTAGVIGTGKIGVAML
                     RILKGFGMRLLAFDPYPSAAALELGVEYVDLPTLFSESDVISLHCPLTPENYHLLNEA
                     AFEQMKNGVMIVNTSRGALIDSQAAIEALKNQKIGSLGMDVYENERDLFFEDKSNDVI
                     QDDVFRRLSACHNVLFTGHQAFLTAEALTSISQTTLQNLSNLEKGETCPNELV"
     gene            26673..27095
                     /gene="hslJ"
                     /locus_tag="IRB70_000354"
     CDS             26673..27095
                     /gene="hslJ"
                     /locus_tag="IRB70_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HslJ"
                     /protein_id="HBC0630312.1"
                     /translation="MKKVAAFVALSLLMAGCVSNDKIAVTPEQLQHHRFVLESVNGKP
                     VTSDKNPPEISFGEKMMISGSMCNRFSGEGKLSNGELTAKGLAMTRMMCANPQLNELD
                     NTISEMLKEGAQVDLTANQLTLATAKQTLTYKLADLMN"
     gene            complement(27092..27358)
                     /locus_tag="IRB70_000355"
     CDS             complement(27092..27358)
                     /locus_tag="IRB70_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing protein"
                     /protein_id="HBC0630313.1"
                     /translation="MRAAFWVGCAALLLSACSSEPVQQATAAHVAPGLKASMSSSGEA
                     NCAMIGGSLSVARQLDGTAIGMCALPNGKRCSEQSLAAGSCGSY"
     gene            27632..31156
                     /gene="nifJ"
                     /locus_tag="IRB70_000356"
     CDS             27632..31156
                     /gene="nifJ"
                     /locus_tag="IRB70_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBC0630314.1"
                     /translation="MITIDGNGAVASVAFRTSEVIAIYPITPSSTMAEQADAWAGNGL
                     KNVWGDTPRVVEMQSEAGAIATVHGALQTGALSTSFTSSQGLLLMIPTLYKLAGELTP
                     FVLHVAARTVATHALSIFGDHSDVMAVRQTGCAMLCAANVQEAQDFALISHIATLKSR
                     VPFIHFFDGFRTSHEINKIVPLADDTILDLMPQAEIDAHRARALNPEHPVIRGTSANP
                     DTYFQSREATNPWYNAVYDHVEQAMNDFAAATGRQYQPFEYYGHPQAERVIILMGSAI
                     GTCEEVVDELLTRGEKVGVLKVRLYRPFSAKHLLQALPGSVRSVAVLDRTKEPGAQAE
                     PLYLDVMTALAEAFNNGERETLPRVIGGRYGLSSKEFGPDCVLAVFAELNAAKPKARF
                     TVGIYDDVTNLSLPLPDNTLPNSAKLEALFYGLGSDGSVSATKNNIKIIGNSTPWYAQ
                     GYFVYDSKKAGGLTVSHLRVSEQPIRSAYLIPQADFVGCHQLQFIDKYQMAERLKPGG
                     IFLLNTPYSADEVWSRLPQEVQAVLNQKKARFYVINAAKIARECGLAARINTVMQMAF
                     FHLTQILPGDSALAELQGAIAKSYSSKGQDLVERNWQALALARESVEEVPLQPVNPHS
                     ANRPPVVSDAAPDFVKTVTAAMLAGLGDALPVSALPPDGTWPMGTTRWEKRNIAEEIP
                     IWKEELCTQCNHCVAACPHSAIRAKVVPPEAMENAPASLHSLDVKSRDMRGQKYVLQV
                     APEDCTGCNLCVEVCPAKDRQNPEIKAINMMSRLEHVEEEKINYDFFLNLPEIDRSKL
                     ERIDIRTSQLITPLFEYSGACSGCGETPYIKLLTQLYGDRMLIANATGCSSIYGGNLP
                     STPYTTDANGRGPAWANSLFEDNAEFGLGFRLTVDQHRVRVLRLLDQFADKIPAELLT
                     ALKSDATPEIRREQVAALRQQLNDVAEAHELLRDADALVEKSIWLIGGDGWAYDIGFG
                     GLDHVLSLTENVNILVLDTQCYSNTGGQASKATPLGAVTKFGEHGKRKARKDLGVSMM
                     MYGHVYVAQISLGAQLNQTVKAIQEAEAYPGPSLIIAYSPCEEHGYDLALSHDQMRQL
                     TATGFWPLYRFDPRRADEGKLPLALDSRPPSEALEETLLHEQRFRRLNSQQPEVAEQL
                     WKDAAADLQKRYDFLAQMAGKAEKSNTD"
     gene            31517..32650
                     /gene="ompN"
                     /locus_tag="IRB70_000357"
     CDS             31517..32650
                     /gene="ompN"
                     /locus_tag="IRB70_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpN"
                     /protein_id="HBC0630315.1"
                     /translation="MKSKVLALLIPALLAAGAAHAAEVYNKDGNKLDLYGKVDGLHYF
                     SDNSAKDGDQSYARLGFKGETQINDQLTGYGQWEYNIQANNTESSTNQSWTRLAFAGL
                     KFADYGSFDYGRNYGVMYDIEGWTDMLPEFGGDSYTNADNFMTGRANGVATYRNTDFF
                     GLVNGLNFAVQYQGNNEGASNGQEGTNNGRDVRHENGDGWGLSTTYDLGMGFSAGAAY
                     TSSDRTNDQVNHTAAGGDKADAWTAGLKYDANNIYLATMYSETRNMTPFGDSDYAVAN
                     KTQNFEVTAQYQFDFGLRPAVSFLMSKGRDLHAAGGADNPAGVDDKDLVKYADVGATY
                     YFNKNMSTYVDYKINLLDEDDSFYAANGISTDDIVALGLVYQF"
     gene            32791..33225
                     /gene="uspF"
                     /locus_tag="IRB70_000358"
     CDS             32791..33225
                     /gene="uspF"
                     /locus_tag="IRB70_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310024.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspF"
                     /protein_id="HBC0630316.1"
                     /translation="MNRTILVPIDISDSELTQRVISHVEAEAKIDDAEVHFLTVIPSL
                     PYYASLGLAYSAELPAMDDLKAEAKSQLEEIIKKFKLPTDRVHVHVEEGSPKDRILEL
                     AKKIPAHMIIIASHRPDITTYLLGSNAAAVVRHAECSVLVVR"
     gene            33401..34336
                     /gene="ttcA"
                     /locus_tag="IRB70_000359"
     CDS             33401..34336
                     /gene="ttcA"
                     /locus_tag="IRB70_000359"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiocytidine(32) synthetase TtcA"
                     /protein_id="HBC0630317.1"
                     /translation="MSQNQEISKKEQYNLNKLQKRLRRNVGEAIADFNMIEEGDRIMV
                     CLSGGKDSYTMLEILRNLQQSAPINFSLVAVNLDQKQPGFPEHVLPEYLEKLGVEYKI
                     VEENTYGIVKEKIPEGKTTCSLCSRLRRGILYRTATELGATKIALGHHRDDILQTLFL
                     NMFYGGKMKGMPPKLMSDDGKHIVIRPLAYCREKDIQRFADAKAFPIIPCNLCGSQPN
                     LQRQVIADMLRDWDKRYPGRIETMFSAMQNVVPSHLCDTNLFDFKGITHGSEVVNGGD
                     LAFDREEIPLQPAGWQPEEDENQLDELRLNVVEVK"
     gene            complement(34465..35838)
                     /gene="dbpA"
                     /locus_tag="IRB70_000360"
     CDS             complement(34465..35838)
                     /gene="dbpA"
                     /locus_tag="IRB70_000360"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707684.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DbpA"
                     /protein_id="HBC0630318.1"
                     /translation="MTAFSTLNVLPPAQLTNLNELGYLTMTPVQAAALPAILAGKDVR
                     VQAKTGSGKTAAFGLGLLQQIDASLFQTQALVLCPTRELADQVAGELRRLARFLPNTK
                     ILTLCGGQPFGMQRDSLQHAPHIIVATPGRLLDHLQKGTVSLDALNTLVMDEADRMLD
                     MGFSDAIDDVIRFAPASRQTLLFSATWPEAIAAISGRVQRDPLAIEIDSTDALPPIEQ
                     QFYETSSKGKIPLLQRLLSLHQPSSCVVFCNTKKDCQAVCDALNEVEQSALSLHGDLE
                     QRDRDQTLVRFANGSARVLVATDVAARGLDIKSLELVVNFELAWDPEVHVHRIGRTAR
                     AGNSGLAISFCAPEEAQRANIISDMLQIKLNWQTPPVNSSIVPLEAEMATLCIDGGKK
                     AKMRPGDVLGALTGDIGLDGADIGKIAVHPAHVYVAVRQAVAHKAWKQLQGGKIKGKT
                     CRVRLLK"
     gene            complement(36316..37299)
                     /gene="zntB"
                     /locus_tag="IRB70_000361"
     CDS             complement(36316..37299)
                     /gene="zntB"
                     /locus_tag="IRB70_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZntB"
                     /protein_id="HBC0630319.1"
                     /translation="MEAIKGSDVNVPDAVFAWMLDGRGGVKPLENTDVIDEAHPCWLH
                     LNYVHHDSAQWLATTPLLPNNVRDALAGESTRPRVSRLGEGTLITLRCINGSTDERPD
                     QLVAMRVYMDGRLIVSTRQRKVLALDDVVSDLEEGTGPTDCGGWLVDVCDALTDHSSE
                     FIEQLHDKIIDLEDNLLDQQIPPRGFLALLRKQLIVMRRYMAPQRDVYARLASERLPW
                     MSDDQRRRMQDIADRLGRGLDEIDACIARTGVMADEIAQVMQENLARRTYTMSLMAMV
                     FLPSTFLTGLFGVNLGGIPGGGWQFGFSIFCILLVVLIGGVALWLHRSKWL"
     gene            37554..38786
                     /gene="dgcM"
                     /locus_tag="IRB70_000362"
     CDS             37554..38786
                     /gene="dgcM"
                     /locus_tag="IRB70_000362"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcM"
                     /protein_id="HBC0630320.1"
                     /translation="MITHNFNTLDLLTSPVWIVSPFEEQLIYANSAARLLMQDLTFSQ
                     LRTGPYSVSSQKELPKYLSDLQNQHDIIEILTVQRKEEETALSCRLVLRELTETEPVI
                     IFEGIEAPATLGLKASRSANYQRKKQGFYARFFLTNSAPMLLIDPSRDGQIVDANLAA
                     LNFYGYNHETMCQKHTWEINMLGRRVMPIMHEISHLPGGHKPLNFVHKLADGSTRHVQ
                     TYAGPIEIYGDKLMLCIVHDITEQKRLEEQLEHAAHHDAMTGLLNRRQFYHITEPGQM
                     QHLAIAQDYSLLLIDTDRFKHINDLYGHSKGDEVLCALARTLESCARKGDLVFRWGGE
                     EFVLLLPRTPLDTALSLAETIRVSVAKVSISGLPRFTVSIGVAHHEGNESIDELFKRV
                     DDALYRAKNDGRNRVLAA"
     gene            complement(38807..39370)
                     /gene="smrA"
                     /locus_tag="IRB70_000363"
     CDS             complement(38807..39370)
                     /gene="smrA"
                     /locus_tag="IRB70_000363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA endonuclease SmrA"
                     /protein_id="HBC0630321.1"
                     /translation="MNLDDKSLFLDAMEDVQPLKRATDVHWHPTRNQRAPQRIDTLQL
                     DNFLTTGFLDIIPLTQPLEFRREGLQHGVLDKLRSGKYPQQASLNLLRQPVEECRKMV
                     FSFIQQALADGLRNVLIIHGKGREDKSHANIVRSYVARWLTEFDDVQAYCTALPHHGG
                     SGACYVALRKTAQAKQENWERHAKRSR"
     gene            complement(39700..40608)
                     /locus_tag="IRB70_000364"
     CDS             complement(39700..40608)
                     /locus_tag="IRB70_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0630322.1"
                     /translation="MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELE
                     EGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELRAAQEDIRQRQGQLAGQINIGMG
                     ASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
                     FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQT
                     PQVGVVCETFSACISLVAKSDFLSILPEEMGCDPLHGQGLVMLPVSEILPKAAYYLIQ
                     RRDSRQTPLTASLITQFRRECGYLQS"
     gene            40784..42079
                     /gene="abgA"
                     /locus_tag="IRB70_000365"
     CDS             40784..42079
                     /gene="abgA"
                     /locus_tag="IRB70_000365"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415854.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgA"
                     /protein_id="HBC0630323.1"
                     /translation="MESLNQFINSLAPKLSHWRRDFHHYAESGWVEFRTATVVAEELH
                     QLGYSLALGREVVNESSRMGLPDEFTLQREFERARQQGALEQWIAAFEGGFTGIVATL
                     DTGRPGPVMAFRVDMDALDLSEEQDVSHRPYRDGFASCNAGMMHACGHDGHTAIGLGL
                     AHTLKQFESGLHGVIKLIFQPAEEGTRGARAMVDAGVVDDVDYFTAVHIGTGVPAGTV
                     VCGSDNFMATTKFDAHFTGTAAHAGAKPEDGHNALLAAAQATLALHAIAPHSEGASRV
                     NVGVMQAGSGRNVVPASALLKVETRGASDVINQYVFDRAQQAIQGAATMYGVGVETRL
                     MGAATASSPSPQWVAWLQSQAAQVAGVNQAIERVEAPAGSEDATLMMARVQQHQGQAS
                     YMVFGTQLAAGHHNEKFDFDEQVLTIAVETLARTALNFP"
     gene            42094..43539
                     /gene="abgB"
                     /locus_tag="IRB70_000366"
     CDS             42094..43539
                     /gene="abgB"
                     /locus_tag="IRB70_000366"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate hydrolase subunit AbgB"
                     /protein_id="HBC0630324.1"
                     /translation="MQEIYRFIDDAIEADRQRYTDIADQIWDHPETRFEEFWSAEHLA
                     SALESSGFIVTRNVGNIPNAFIASFGQGKPVIALLGEYDALAGLSQQASCAQPTSATP
                     GENGHGCGHNLLGTAAFAAAIAVKKWLEQYGQGGTVRFYGCPGEEGGSGKTFMVREGV
                     FDDVDAALTWHPEAFAGMFNTRTLANIQASWRFKGIAAHAANSPHLGRSALDAVTLMT
                     TGTNFLNEHIIEKARVHYAITDSGGISPNVVQAQAEVLYLIRAPEMTDVQHIYDRVAK
                     IAEGAALMTETTVECRFDKACSSYLPNRTLENAMYRALSHFGTPEWNCEELAFAKQIQ
                     ATLTPNDRQNSLNNIAATGGENGKAFALRHRETVLANEVAPYAATDNVLAASTDVGDV
                     SWKLPVAQCFSPCFAVGTPLHTWQLVSQGRTSIAHKGMLLAAKTMAATTLNLFIDSGL
                     LQECQQEHQQVTDTQPYHCPIPKNVTPSPLK"
     gene            43576..45102
                     /gene="abgT"
                     /locus_tag="IRB70_000367"
     CDS             43576..45102
                     /gene="abgT"
                     /locus_tag="IRB70_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415852.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-aminobenzoyl-glutamate transporter"
                     /protein_id="HBC0630325.1"
                     /translation="MSMSSIPSSSQSGKLYGWVERIGNKVPHPFLLFIYLIIVLMVTT
                     AILSAFGVSAKNPTDGTPVVVKNLLSVEGLHWFLPNVIKNFSGFAPLGAILALVLGAG
                     LAERVGLLPALMVKMASHVNARYASYMVLFIAFFSHISSDAALVIMPPMGALIFLAVG
                     RHPVAGLLAAIAGVGCGFTANLLIVTTDVLLSGISTEAAAAFNPQMHVSVIDNWYFMA
                     SSVVVLTIVGGLITDKIIEPRLGQWQGNSDEKLQTLTESQRFGLHIAGVVSLLFIAAI
                     ALMVIPENGILRDPINHTVMPSPFIKGIVPLIILFFFVVSLAYGIATRTIRRQADLPH
                     LMIEPMKEMAGFIVMVFPLAQFVAMFNWSNMGKFIAVGLTDILESSGLSGIPAFVGLA
                     LLSSFLCMFIASGSAIWSILAPIFVPMFMLLGFHPAFAQILFRIADSSVLPLAPVSPF
                     VPLFLGFLQRYKPDAKLGTYYSLVLPYPLIFLVVWLLMLLAWYLVGLPIGPGIYPRLS
                     "
     gene            45113..45628
                     /gene="ogt"
                     /locus_tag="IRB70_000368"
     CDS             45113..45628
                     /gene="ogt"
                     /locus_tag="IRB70_000368"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBC0630326.1"
                     /translation="MLRLLEEKIVTPLGPLWVICDEQFRLRAVEWEEYSERMVQLLDI
                     HYRKEGYERISATNPGGLSDKLREYFAGNLSIIDTLPTATGGTPFQREVWKTLRTIPC
                     GQVMHYGQLAEQLGRPGAARAVGAANGSNPISIVVPCHRVIGRNGTMTGYAGGVQRKE
                     WLLRHEGYLLL"
     gene            45823..46575
                     /gene="fnr"
                     /locus_tag="IRB70_000369"
     CDS             45823..46575
                     /gene="fnr"
                     /locus_tag="IRB70_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007849744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate/nitrate reduction transcriptional
                     regulator Fnr"
                     /protein_id="HBC0630327.1"
                     /translation="MIPEKRIIRRIQSGGCAIHCQDCSISQLCIPFTLNEHELDQLDN
                     IIERKKPIQKGQTLFKAGDELKSLYAIRSGTIKSYTITEQGDEQITGFHLAGDLVGFD
                     AIGSGHHPSFAQALETSMVCEIPFETLDDLSGKMPNLRQQMMRLMSGEIKGDQDMILL
                     LSKKNAEERLAAFIYNLSRRFAQRGFSPREFRLTMTRGDIGNYLGLTVETISRLLGRF
                     QKSGMLAVKGKYITIENNDALAQLAGHTRNVA"
     gene            46727..47677
                     /gene="uspE"
                     /locus_tag="IRB70_000370"
     CDS             46727..47677
                     /gene="uspE"
                     /locus_tag="IRB70_000370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspE"
                     /protein_id="HBC0630328.1"
                     /translation="MAMYQNMLVVIDPNQDDQPALRRAVYLHQRIGGKIKAFLPIYDF
                     SYEMTTLLSPDERTAMRQGVISQRTAWIHEQAKYYLNAGVPIEIKVVWHNRPFEAIIQ
                     EVISGGHDLVLKMAHQHDRLEAVIFTPTDWHLLRKCPSPVWMVKDQPWPEGGKALVAV
                     NLASEEPYHNALNEKLVKETIELAEQVNHTEVHLVGAYPVTPINIAIELPEFDPSVYN
                     DAIRGQHLLAMKALRQKFGINENMTHVEKGLPEEVIPDLAEHLQAGIVVLGTVGRTGI
                     SAAFLGNTAEQVIDHLRCDLLVIKPDQYQTPVELDDEEDD"
     gene            complement(47727..47984)
                     /locus_tag="IRB70_000371"
     CDS             complement(47727..47984)
                     /locus_tag="IRB70_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2534 family protein"
                     /protein_id="HBC0630329.1"
                     /translation="MIMAKLKSAKGKKFLFGLLAVFIIAASVVTRATIGGVIEQYNIP
                     LSEWTTSMYVIQSSMIFVYSLVFTVLLAIPLGIYFLGGEEQ"
     gene            48228..49259
                     /gene="ynaI"
                     /locus_tag="IRB70_000372"
     CDS             48228..49259
                     /gene="ynaI"
                     /locus_tag="IRB70_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low conductance mechanosensitive channel YnaI"
                     /protein_id="HBC0630330.1"
                     /translation="MIAELFTNNALNLVIIFGSCAALILMSFWFRRGNRKRKGFLFHA
                     VQFLIYTIIISAVGSIINYVIENYKLKFITPGVIDFICTSLIAVILTIKLFLLINQFE
                     KQQIKKGRDITSARIMSRIIKITIIVVLVLLYGEHFGMSLSGLLTFGGIGGLAVGMAG
                     KDILSNFFSGIMLYFDRPFSIGDWIRSPDRNIEGTVAEIGWRITKITTFDNRPLYVPN
                     SLFSSISVENPGRMTNRRITTTIGLRYEDAAKVGVIVEAVREMLKNHPAIDQRQTLLV
                     YFNQFADSSLNIMVYCFTKTTVWAEWLAAQQDVYLKIIDIVQSHGADFAFPSQTLYMD
                     NITPPDQGR"
     gene            complement(49310..50923)
                     /gene="mppA"
                     /locus_tag="IRB70_000373"
     CDS             complement(49310..50923)
                     /gene="mppA"
                     /locus_tag="IRB70_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415845.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide ABC transporter
                     substrate-binding protein MppA"
                     /protein_id="HBC0630331.1"
                     /translation="MKHSVSVTCCALLVSSISLSYAAEVPSGTVLAEKQELVRHIKDE
                     PASLDPAKAVGLPEIQVIRDLFEGLVNQNEKGEIVPGVATQWKSNDNRIWTFTLRDNA
                     KWADGTPVTAQDFVYSWQRLVDPKTLSPFAWFAALAGINNAQAIIDGKATPDQLGVTA
                     VDAHTLKIQLDKPLPWFVNLTANFAFFPVQKANVESSKEWTKPGNLIGNGAYVLKERV
                     VNEKLVVVPNTHYWDNAKTVLQKVTFLPINQESAATKRYLAGDIDITESFPKNMYQKL
                     LKDIPGQVYTPPQLGTYYYAFNTQKGPTADQRVRLALSMTIDRRLMTEKVLGTGEKPA
                     WHFTPDVTAGFTPEPSPFEQMSQEELNAQAKTLLSAAGYGPQKPLKLTLLYNTSENHQ
                     KIAIAVASMWKKNLGVDVKLQNQEWKTYIDSRNTGNFDVIRASWVGDYNEPSTFLTLL
                     TSTHSGNISRFNNPAYDKVLAQASTENTVKARNADYNAAEKILMEQAPIAPIYQYTNG
                     RLIKPWLKGYPINNPEDVAYSRTMYIVKH"
     gene            51106..51834
                     /gene="mpaA"
                     /locus_tag="IRB70_000374"
     CDS             51106..51834
                     /gene="mpaA"
                     /locus_tag="IRB70_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide amidase MpaA"
                     /protein_id="HBC0630332.1"
                     /translation="MTVTRPRAERGAFPPGTEHYGRSLLGAPLIWFPAPAASHESGLI
                     LAGTHGDENSSIVTLSCALRTLTPSLRRHHVVLCVNPDGCQLGLRANANGVDLNRNFP
                     AANWKEGETVYRWNSTAEERDVVLLTGDKPGSEPETQALCQLIHRIQPAWVVSFHDPL
                     ACIEDPRHSELGEWLAQAFELPLVTSVGYETPGSFGSWCADLNLHCITAEFPPISSDE
                     ASEKYLFAMANLLRWHPKDAIRPL"
     gene            complement(51809..52774)
                     /gene="ycjG"
                     /locus_tag="IRB70_000375"
     CDS             complement(51809..52774)
                     /gene="ycjG"
                     /locus_tag="IRB70_000375"
                     /EC_number="5.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-Ala-D/L-Glu epimerase"
                     /protein_id="HBC0630333.1"
                     /translation="MRTVKVFEEAWPLHTPFVIARGSRSEARVVVVELEEDGVKGTGE
                     CTPYPRYGESDASVMAQIMSVVPQLEKGLTREELQKILPAGAARNALDCALWDLAARK
                     QQQSLADLIGITLPETVTTAQTIVIGTPDQMANSASTLWQAGAKLLKVKLDNHLISER
                     MVAIRTAVPDATLIVDANESWRAEGLAARCQLLADLGVAMLEQPLSAQDDAALENFIH
                     PLPICADESCHTRSNLKALKGRYEMVNIKLDKTGGLTEALALATEARAQGFRLMLGCM
                     LCTSRAISAALPLVPQVSFADLDGPTWLAVDVEPALQFTTGELHL"
     gene            52893..53399
                     /gene="tpx"
                     /locus_tag="IRB70_000376"
     CDS             52893..53399
                     /gene="tpx"
                     /locus_tag="IRB70_000376"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol peroxidase"
                     /protein_id="HBC0630334.1"
                     /translation="MSQTVHFQGNPVTVANSIPQAGSKAQTFTLVAKDLSDVTLGQFA
                     GKRKVLNIFPSIDTGVCAASVRKFNQLATEIDNTVVLCISADLPFAQSRFCGAEGLNN
                     VITLSTFRNAEFLQAYGVAIADGPLKGLAARAVVVIDENDNVIFSQLVDEITTEPDYE
                     AALAVLKA"
     gene            complement(53443..54984)
                     /gene="tyrR"
                     /locus_tag="IRB70_000377"
     CDS             complement(53443..54984)
                     /gene="tyrR"
                     /locus_tag="IRB70_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TyrR"
                     /protein_id="HBC0630335.1"
                     /translation="MRLEVFCEDRLGLTRELLDLLVLRGIDLRGIEIDPIGRIYLNFA
                     ELEFESFSSLMAEIRRIAGVTDVRTVPWMPSEREHLALSALLEALPEPVLSVDMKSKV
                     DMANPASCQLFGQKLDRLRNHTAAQLINGFNFLRWLESEPQDSHNEHVVINGQNFLME
                     ITPVYLQDENDQHVLTGAVVMLRSTIRMGRQLQNVAAQDVSAFSQIVAVSPKMKHVVE
                     QAQKLAMLSAPLLITGDTGTGKDLFAYACHQASPRASKPYLALNCASIPEDAVESELF
                     GHAPEGKKGFFEQANGGSVLLDEIGEMSPRMQAKLLRFLNDGTFRRVGEDHEVHVDVR
                     VICATQKNLVELVQKGVFREDLYYRLNVLTLNLPPLRDCPQDIMPLTELFVARFADEQ
                     GVPRPKLAADLNTVLTRYAWPGNVRQLKNAIYRALTQLDGYELRPQDILLPDYDAATV
                     AVGEDAMEGSLDEITSRFERSVLTQLYRNYPSTRKLAKRLGVSHTAIANKLREYGLSQ
                     KKNEE"
     gene            complement(55132..56193)
                     /locus_tag="IRB70_000378"
     CDS             complement(55132..56193)
                     /locus_tag="IRB70_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01620 family protein"
                     /protein_id="HBC0630336.1"
                     /translation="MTEPLKPRIDFDGPLDVDQNPEFRAQQTFDENQAQNFAPATLDE
                     AQEEEGQVEAVMDAALRPKRSLWRKMVMGGLALFGASVVGQGVQWTMNAWQTQDWVAL
                     GGCAAGALIIGAGVGSVVTEWRRLWRLRQRAHERDEARDLLHSHGTGKGRAFCEKLAQ
                     QAGIDQSHPALQRWYASIHETQNDREVVSLYAHLVQPVLDAQARREISRSAAESTLMI
                     AVSPLALVDMAFIAWRNLRLINRIATLYGIELGYYSRLRLFKLVLLNIAFAGASELVR
                     EVGMDWMSQDLAARLSTRAAQGIGAGLLTARLGIKAMELCRPLPWIDDDKPRLGDFRR
                     QLIGQVKETLQKGKTPSEK"
     gene            complement(56190..57587)
                     /locus_tag="IRB70_000379"
     CDS             complement(56190..57587)
                     /locus_tag="IRB70_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcjX family protein"
                     /protein_id="HBC0630337.1"
                     /translation="MKRLKNELNALVNRGVDRHLRLAVTGLSRSGKTAFITAMVNQLL
                     NIHAGARLPLLSAVREERLLGVKRIPQRDFGIPRFTYDEGLAQLYGDPPAWPTPTRGV
                     SEIRLALRFKSNDSLLRHFKDTSTLYLEIVDYPGEWLLDLPMLAQDYLSWSRQMTGLL
                     NGQRGEWSAKWRMMCEGLDPLAPADENRLADIAAAWTDYLHHCKQQGLHFIQPGRFVL
                     PGDMAGAPALQFFPWPDVDAWGESKLAQADKHTNAGMLRERFNYYCEKVVKGFYKNHF
                     LRFDRQIVLVDCLQPLNSGPQAFNDMRLALTQLMQSFHYGQRTLFRRLFSPVIDKLLF
                     AATKADHVTIDQHANMVSLLQQLIQDAWQNAAFEGISMDCLGLASVQATTSGIIDVNG
                     EKIPALRGNRLSDGAPLTVYPGEVPARLPGQAFWDKQGFQFEAFRPQVMDVDKPLPHI
                     RLDAALEFLIGDKLR"
     gene            57742..58740
                     /locus_tag="IRB70_000380"
     CDS             57742..58740
                     /locus_tag="IRB70_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBC0630338.1"
                     /translation="MSPTIYDIARVAGVSKSTVSRVLNKQTNISPEAREKVLRAIEEL
                     QYQPNKLARALTSSGFDAIMVISTRSTKTTAGNPFFSEVLHAITAKAEEEGFDVILQT
                     SHNPAEDLQKCESKIKQKMIKGIIMLSSPADESFFAQLDKYEIPVVVIGKVEGQYSHV
                     YSVDTDNYGDSIALTNALIESGHKNIACLHAPLDVHVSVDRVNGYKQSLATHNIAVRD
                     EWIVDGGYTHETALQAARELLSQSPLPEAVFATDSLKLMSIYRAAAEKNIAIPQQLAV
                     VGYSNETLSFILTPAPGGIDVPTQELGQQSCELLFQLIAGKPSPQNITVATHMSLK"
     gene            complement(58791..59696)
                     /gene="ompG"
                     /locus_tag="IRB70_000381"
     CDS             complement(58791..59696)
                     /gene="ompG"
                     /locus_tag="IRB70_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monomeric porin OmpG"
                     /protein_id="HBC0630339.1"
                     /translation="MKKLLPCTALVMCAGMACAQAEEKNDWHFNIGAMYEIENVEGYG
                     EDMDGLAEPSVYFNAANGPWRISLAYYQEGPVDYSAGKRGTWFDRPELEVHYQFLESD
                     DFSFGLTGGFRNYGYHYVDEPGKDTANMQRWKIAPDWDVKLTDDLRFNGWLSMYKFAN
                     DLNTTGYADTRVETETGLQYTFNETVALRVNYYLERGFNMDDSRNNGEFSTQEIRAYL
                     PLTLGNHSVTPYTRIGLDRWSNWDWLDDIEREGHDFNRVGLFYGYDFQNGLSVSLEYA
                     FEWQDHDEGDSDKFHYAGVGVNYSF"
     gene            complement(59741..60823)
                     /locus_tag="IRB70_000382"
     CDS             complement(59741..60823)
                     /locus_tag="IRB70_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0630340.1"
                     /translation="MAQLSLQHIQKIYDNQVHVVKDFNLEIADKEFIVFVGPSGCGKS
                     TTLRMIAGLEEISGGDLLIDGKRMNDVPAKARNIAMVFQNYALYPHMTVYDNMAFGLK
                     MQKIAKEVIDERVNWAAQILGLREYLKRKPGALSGGQRQRVALGRAIVREAGVFLMDE
                     PLSNLDAKLRVQMRAEISKLHQKLNTTMIYVTHDQTEAMTMATRIVIMKDGIVQQVGA
                     PKTVYNQPANMFVAGFIGSPAMNFIRGTIDGDKFVTETLKLTIPEEKLAVLKTQESLH
                     KPIVMGIRPEDIHPDAQEENNISAKISVAELTGAEFMLYTTVGGHELVVRAGALNDYH
                     AGENITIHFDMTKCHFFDAETEIAIR"
     gene            complement(60837..61496)
                     /gene="pgmB"
                     /locus_tag="IRB70_000383"
     CDS             complement(60837..61496)
                     /gene="pgmB"
                     /locus_tag="IRB70_000383"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBC0630341.1"
                     /translation="MKLQGVIFDLDGVITDTAHLHFQAWQQIAAEIGISIDAQFNEFL
                     KGISRDESLRRILQHGGKEGDFNPQERAQLAYRKNLLYVHSLRELTVNAVLPGIHNLL
                     VELRAQQIPVGLASVSLNAPTILAALELREFFTFCADASQLKNSKPDPEIFLAACAGL
                     GVPPQACIGIEDAQAGIEAINASGMRSVGIGAGLTGAQLLLPSTESLTWSRLSAFWQN
                     V"
     gene            complement(61493..63760)
                     /locus_tag="IRB70_000384"
     CDS             complement(61493..63760)
                     /locus_tag="IRB70_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBC0630342.1"
                     /translation="MTRPVTLTEPHFSQHTLNKYASLMAQGNGYLGLRASHEEDYTRQ
                     TRGMYLAGLYHRAGKNDINELVNLPDVIGMEITLNGELFALSRETWQRELDFASGELR
                     RNVVWSSASGARYAIASRRFVSAEQLPLMALEISITPLDADASVLISTGIDATQTNHG
                     RQHLDETQVRVFGQHLMQGIYTTQDGRSDVAISCCCQVSGDVQQCYTAKERRLLQHTS
                     AQLPAGKTLTLQKRVWIDWRDDRHVALDEWGSASLRQLEMCVQQSYDQLLAASTENWR
                     QWWQKRRITVNGGDAHDQQALDYALYHLRIMTPAHDERSSIAAKGLTGEGYKGHVFWD
                     TEVFLLPFHLFSEPTIARSLLRYRWHNLPGAQEKARRNGWQGALFPWESARSGEEETP
                     EFAAINIRTGLRQKVASAQAEHHLVADIAWAVVQYWQTTGDESFIAHEGMALLLETAK
                     FWISRTVRVNDRLEIHDVIGPDEYTEHVNNNAFTSYMAYYNVQQALNIARQFGCSDDA
                     FIHRAEMFLKELRLPEIQPDRVLPQDDSFMAKPAINLAKYKAAAGKQTILLDYSRAEV
                     NEMQILKQADVVMLNYMLPEQYSAASCLANLQFYEPRTIHDSSLSKAIHGIVAARCGL
                     LAQSYQFWREGTEIDLGADPHSCDDGIHAAATGAIWLGAIQGFAGASVRNGELHLNPA
                     LPEQWQQLSFPLFWQGCELQVTLDAQRIAIRTSAPVSLRLNGQLISVSEESVFCLGDF
                     ILPFNGTATTHQEGE"
     gene            complement(63757..64812)
                     /locus_tag="IRB70_000385"
     CDS             complement(63757..64812)
                     /locus_tag="IRB70_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBC0630343.1"
                     /translation="MKSAMTSSPLRVAIIGAGQVADKVHASYYCTRNDLELVAVCDSR
                     LSQAQALAEKYGNASVWDDPQAMLLAVKPDVVSVCSPNRFHYEHTLMALEAGCHVMCE
                     KPPAMTPEQAREMCDTARKQGKVLAYDFHHRFALDTQQLREQVTNGVLGEIYVTTARA
                     LRRCGVPGWGVFTNKELQGGGPLIDIGIHMLDAAMYVLGFPAVKSVTAHSFQKIGTQK
                     SCGQFGEWDPATYSVEDSLFGTIEFHNGGILWLETSFALNIREQSIMNVSFCGDKAGA
                     TLFPAHIYTDNNGELMTLMQREMADDNRHLRSMEAFINHVQGKPVMIADAEQGYIIQQ
                     LVAALYQSAETGTRVEL"
     gene            complement(64822..65610)
                     /locus_tag="IRB70_000386"
     CDS             complement(64822..65610)
                     /locus_tag="IRB70_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415830.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBC0630344.1"
                     /translation="MKIGTQNQAFFPENILEKFRYIKEMGFDGFEIDGKLLVNNIEEV
                     KAAIKETGLPVTTACGGYDGWIGDFIEERRLNGLKQIERILEALAEVGGKGIVVPAAW
                     GMFTFRLPPMTSPRSLDGDRKMVSDSLRVLEQVAARTGTVVYLEPLNRYQDHMINTLA
                     DARRYIVENDLKHVQIIGDFYHMNIEEDNLAQALHDNRDLLGHVHIADNHRYQPGSGT
                     LDFHALFEQLRADNYQGYVVYEGRIRAEDPAQAYRDSLAWVRTC"
     gene            complement(65628..66680)
                     /locus_tag="IRB70_000387"
     CDS             complement(65628..66680)
                     /locus_tag="IRB70_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBC0630345.1"
                     /translation="MKKLVATAPRVAALVEYEDRAILANEVKIRVRFGAPKHGTEVVD
                     FRAASPFIDEDFNGEWQMFTPRPADAPRGIEFGKFQLGNMVVGDIIECGSDVTDYAVG
                     DSVCGYGPLSETVIINAVNNYKLRKMPQGSSWKNAVCYDPAQFAMSGVRDANVRVGDF
                     VVVVGLGAIGQIAIQLAKRAGASVVIGVDPITRRCEIARRHGADFCLNPIGADVGKEI
                     KTLTGKQGADVIIETSGYADALQSALRGLAYGGTISYVAFAKPFAEGFNLGREAHFNN
                     AKIVFSRACSEPNPDYPRWSRKRIEETCWELLMNGYLNCEDLIDPVVTFANSPESYMQ
                     YVDQHPEQSIKMGVTF"
     gene            complement(66711..67553)
                     /locus_tag="IRB70_000388"
     CDS             complement(66711..67553)
                     /locus_tag="IRB70_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBC0630346.1"
                     /translation="MATNKRTLSRIGFYCGLALFLIITLFPFFVMLMTSFKSAKEAIS
                     LHPTLLPQQWTLEHYVDIFNPMIFPFVDYFRNSMVVSVVSSVIAVFLGILGAYALSRL
                     RFKGRMTINASFYTVYMFSGILLVVPLFKIITALGVYDTEMALIITMVTQTLPTAVFM
                     LKSYFDTIPDEIEEAAMMDGLNRLQIIFRITVPLAMSGLISVFVYCFMVAWNDYLFAS
                     IFLSSASNFTLPVGLNALFSTPDYIWGRMMAASLVTALPVVIMYALSERFIKSGLTAG
                     GVKG"
     gene            complement(67540..68421)
                     /locus_tag="IRB70_000389"
     CDS             complement(67540..68421)
                     /locus_tag="IRB70_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBC0630347.1"
                     /translation="MNRLFSGRSDMPFALLLLAPSLLLLGGLVAWPMVSNIEISFLRL
                     PLNPNIESTFVGVSNYVRILSDPGFWHSLWMTVWYTALVVAGSTVLGLAVAMFFNREF
                     RLRKTARSLVILSYVTPSISLVFAWKYMFNNGYGIVNYLGVDLLHLYEQAPLWFDNPG
                     SSFVLVVLFAIWRYFPYAFISFLAILQTIDKSLYEAAEMDGANAWQRFRIVTLPAIMP
                     VLATVVTLRTIWMFYMFADVYLLTTKVDILGVYLYKTAFAFNDLGKAAAISVVLFIII
                     FAVILLTRKRVNLNGNK"
     gene            complement(68442..69734)
                     /locus_tag="IRB70_000390"
     CDS             complement(68442..69734)
                     /locus_tag="IRB70_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBC0630348.1"
                     /translation="MIKSKIVLLSALVSCALISGCKEENKTNVSIEFMHSSVEQERQA
                     VISQLIARFEKENPGITVKQVPVEEDAYNTKVITLSRSGSLPEVIETSHDYAKVMDKE
                     QLIDRLAVATVISNVGEGAFYDGVLRIVRTEDGSAWTGVPVSAWIGGIWYRKDVLAKA
                     GLDEPKNWQQLLDVAQKLNDPANKKYGIALPTAESVLTEQSFSQFALSNQANVFNAEG
                     KITLDTPEMMQALTYYRDLAANTMPGSNDIMEVKDAFMNGTAPMAIYSTYILPAVIKE
                     GDPKNVGFVVPTEKNSAVYGMLTSLTITAGQKSEETEAAEKFVTFMEQADNIADWVMM
                     SPGAALPVNKAVVTTATWKDNDVIKALGDLPNQLISELPNIQVFGAVGDKNFTRMGDV
                     TGSGVVSSMVHNVTVGKADLPGTLQASQKKLDELIEQH"
     gene            complement(69748..71427)
                     /gene="ycjM"
                     /locus_tag="IRB70_000391"
     CDS             complement(69748..71427)
                     /gene="ycjM"
                     /locus_tag="IRB70_000391"
                     /EC_number="2.4.1.352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415825.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosylglycerate phosphorylase"
                     /protein_id="HBC0630349.1"
                     /translation="MKQKITDYLDEIYGGTFTTTHLQKLVTRLESAKRLITLRRKKHW
                     DESDVVLITYADQFHSNDLKPLPTFNQFYPQWLQSIFSHVHLLPFYPWSSDDGFSVID
                     YQQVASEAGEWQDIQQLGECSHLMFDFVCNHMSAKSEWFKNYLQQQPGFEDFFIAVDP
                     QTDLSVVTRPRALPLLTPFQMRDHSTRHLWTTFSDDQIDLNYRSPEVLLAMVDVLLCY
                     LEKGAEYVRLDAVGFMWKEPGTSCIHLEKTHLIIKLLRSIIDDVAPGTVIITETNVPH
                     RDNIAYFGNGDDEAHMVYQFSLPPLVLHAVQKQNVEALCAWAQNLTLPSSNTTWFNFL
                     ASHDGIGLNPLRGLLPESEILALVEALQQEGALVNWKNNPDGTRSPYEMNVTYMDALN
                     RRESSDEERCARFILAHAILLSFPGVPAIYIQSILGSRNDYAGVEKLEYNRAINRKKY
                     YSEEITTELNNKTTLRHAVYHELSRLIKIRRSHNEFHPDNDFTIDTVNSSVMCIQRSN
                     ADGNCLTGLFNVSENIQHINITGLHGRDLISEVDIVGNEITLRPWQVMWIK"
     gene            complement(71641..71955)
                     /gene="pspE"
                     /locus_tag="IRB70_000392"
     CDS             complement(71641..71955)
                     /gene="pspE"
                     /locus_tag="IRB70_000392"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase PspE"
                     /protein_id="HBC0630350.1"
                     /translation="MFKKGLLALALVFSLPVFAAEHWIDVRVPEQYQQEHVQGAINIP
                     LKEVKERIATAVPDKNDTVKVYCNAGRQSGQAKDILSEMGYTHVENAGGLKDIAMPKV
                     KG"
     gene            complement(72030..72251)
                     /gene="pspD"
                     /locus_tag="IRB70_000393"
     CDS             complement(72030..72251)
                     /gene="pspD"
                     /locus_tag="IRB70_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspD"
                     /protein_id="HBC0630351.1"
                     /translation="MNTRWQQAGQKVKPGFKLAGKLVLLTALRYGPAGVAGWAIKSVA
                     RRPLKMLLAVALEPLLSRAANKLAQRYKR"
     gene            complement(72260..72619)
                     /gene="pspC"
                     /locus_tag="IRB70_000394"
     CDS             complement(72260..72619)
                     /gene="pspC"
                     /locus_tag="IRB70_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspC"
                     /protein_id="HBC0630352.1"
                     /translation="MAGINLNKKLWRIPQQGMVRGVCAGIANYFDVPVKLVRILVVLS
                     IFFGLALFTLVAYIILSFALDPMPDNMAFGEQLPSSSELLDEVDRELAASETRLREME
                     RYVTSDTFTLRSRFRQL"
     gene            complement(72619..72843)
                     /gene="pspB"
                     /locus_tag="IRB70_000395"
     CDS             complement(72619..72843)
                     /gene="pspB"
                     /locus_tag="IRB70_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response membrane protein PspB"
                     /protein_id="HBC0630353.1"
                     /translation="MSALFLAIPLTIFVLFVLPIWLWLHYSNRSGRSELSQSEQQRLA
                     QLADEAKRMRERIQALESILDAEHPNWRDR"
     gene            complement(72897..73565)
                     /gene="pspA"
                     /locus_tag="IRB70_000396"
     CDS             complement(72897..73565)
                     /gene="pspA"
                     /locus_tag="IRB70_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein PspA"
                     /protein_id="HBC0630354.1"
                     /translation="MGIFSRFADIVNANINALLEKAEDPQKLVRLMIQEMEDTLVEVR
                     STSARALAEKKQLTRRIEQASAREIEWQEKAELALLKEREDLARAALIEKQKLTDLIK
                     SLEHEVTLVDDTLVRMKKEIGELENKLSETRARQQALMLRHQAANSSRDVRRQLDSGK
                     LDEAMARFESFERRIDQMEAEAESHSFGKQKSLDDQFAELKADDAISEQLAQLKAKMK
                     QDNQ"
     gene            73732..74709
                     /gene="pspF"
                     /locus_tag="IRB70_000397"
     CDS             73732..74709
                     /gene="pspF"
                     /locus_tag="IRB70_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309907.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage shock protein operon transcriptional
                     activator"
                     /protein_id="HBC0630355.1"
                     /translation="MAEYKDNLLGEANSFLEVLEQVSHLAPLDKPVLIIGERGTGKEL
                     IASRLHYLSSRWQGPFISLNCAALNENLLDSELFGHEAGAFTGAQKRHPGRFERADGG
                     TLFLDELATAPMMVQEKLLRVIEYGELERVGGSQPLQVNVRLVCATNADLPAMVNEGT
                     FRADLLDRLAFDVVQLPPLRERESDIMLMAEHFAIQMCREIKLPLFPGFTERARETLL
                     NYRWPGNIRELKNVVERSVYRHGTSDYPLDDIIIDPFKRRPPEDAIAVSEITSLPTLP
                     LDLREFQMQQEKELLQLSLQQGKYNQKRAAELLGLTYHQFRALLKKHQI"
     gene            complement(74829..76094)
                     /gene="puuE"
                     /locus_tag="IRB70_000398"
     CDS             complement(74829..76094)
                     /gene="puuE"
                     /locus_tag="IRB70_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate transaminase"
                     /protein_id="HBC0630356.1"
                     /translation="MSNNEFHQRRLSATPRGVGVMCNFFAQSAENAMLKDVEGNEYID
                     FAAGIAVLNIGHRHPDLVAAVEQQLQQFTHTAYQIVPYESYVTLAEKINALAPVSGQA
                     KTAFFTTGAEAVENAVKIARAHTGRPGVIAFSGGFHGRTYMTMALTGKVAPYKIGFGP
                     FPGSVYHVPYPTDLHGVSTQDSLDAIERLFKSDIEAKQVAAIIFEPVQGEGGFNVAPK
                     ELVAAIRRLCDEHGIVMIADEVQSGFARTGKLFAMDHYADKPDLMTMAKSLAGGMPLS
                     GVVGNANIMDAPAPGGLGGTYAGNPLAVAAAHAVLNIIDKESLCERANQLGQRLTNTL
                     IDAKESVPAIAAVRGLGSMIAAEFNDPQTGEPSAAIAQKIQQRALAQGLLLLTCGAYG
                     NVIRFLYPLTIPDAQFDAAMKILQDALKD"
     gene            complement(76132..77412)
                     /gene="puuB"
                     /locus_tag="IRB70_000399"
     CDS             complement(76132..77412)
                     /gene="puuB"
                     /locus_tag="IRB70_000399"
                     /EC_number="1.4.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylputrescine oxidase"
                     /protein_id="HBC0630357.1"
                     /translation="MTEHTSSYYAASANKYAPFDTLNESISCDVCVVGGGYTGLSSAL
                     HLAEAGFDVVVLEASRIGFGASGRNGGQLVNSYSRDIDVIEKSYGMDTARMLGSMMFE
                     GGEIIRERIKRYQIDCDYRPGGLFVAMNDKQLATLEEQKENWERYGNKQLELLDANAI
                     RREVASDRYTGALLDHSGGHIHPLNLAIGEADAIRLNGGRVYELSAVTQIQHTTPAVV
                     RTANGQVTAKYVIVAGNAYLGDKVEPELAKRSMPCGTQVITTERLSEDLARSLIPKNY
                     CVEDCNYLLDYYRLTADNRLLYGGGVVYGARDPDDVERLVVPKLLKTFPQLKGVKIDY
                     RWTGNFLLTLSRMPQFGRLDTNIYYMQGYSGHGVTCTHLAGRLIAELLRGDAERFDAF
                     ANLPHYPFPGGRTLRVPFTAMGAAYYSLRDRLGV"
     gene            complement(77414..78901)
                     /gene="puuC"
                     /locus_tag="IRB70_000400"
     CDS             complement(77414..78901)
                     /gene="puuC"
                     /locus_tag="IRB70_000400"
                     /EC_number="1.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase PuuC"
                     /protein_id="HBC0630358.1"
                     /translation="MNFYHLAYWQDKALSLAIETRLFINGEYTAAEENETFETVDPVT
                     QAPLAKIARGKSVDIDRAVSAARGVFERGDWSLSSPAKRKAVLNKLADLMEANAEELA
                     LLETLDTGKPIRHSLRDDIPGAARAIRWYAEAIDKVYGEVATTSSHELAMIVREPVGV
                     IAAIVPWNFPLLLTCWKLGPALAAGNSVILKPSEKSPLSAIRLAGLAKEAGLPDGVLN
                     VVTGFGHEAGQALSRHNDIDAIAFTGSTRTGKQLLKDAGDSNMKRVWLEAGGKSANIV
                     FADCPNLQQAASATAAGIFYNQGQVCIAGTRLLLEESIADEFLALLKQQAQNWQPGHP
                     LDPATTMGTLIDCAHADSVHSFIREGESKGQLLLDGRNAELAAAIGPTIFVEVDPNAS
                     LSREEIFGPVLVVTRFTSEEQALQLANDSQYGLGAAVWTRDLSRAHRMSRRLKAGSVF
                     VNNYNDGDMTVPFGGYKQSGNGRDKSLHALEKFTELKTIWISLEA"
     gene            complement(79051..79608)
                     /gene="puuR"
                     /locus_tag="IRB70_000401"
     CDS             complement(79051..79608)
                     /gene="puuR"
                     /locus_tag="IRB70_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001464354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator PuuR"
                     /protein_id="HBC0630359.1"
                     /translation="MSDEGLAPGKRLSEIRQQQGLSQRRAAELSGLTHSAISTIEQDK
                     VSPAISTLQKLLKVYGLSLSEFFSEPEKPDEPQVVINQDDLIEMGSQGVSMKLVHNGN
                     PNRTLAMIFETYQPGTTTGERIKHQGEEIGTVLEGEIVLTINGQDYHLVAGQSYAINT
                     GIPHSFSNTSAGICRIISAHTPTTF"
     gene            complement(79635..80399)
                     /gene="puuD"
                     /locus_tag="IRB70_000402"
     CDS             complement(79635..80399)
                     /gene="puuD"
                     /locus_tag="IRB70_000402"
                     /EC_number="3.5.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415814.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase"
                     /protein_id="HBC0630360.1"
                     /translation="MENIMNNPVIGVVMCRNRLKGHATQTLQEKYLNAIIHAGGLPIA
                     LPHALAEPSLLEQLLPKLDGIYLPGSPSNVQPHLYGENGDEPDADPGRDLLSMALINA
                     ALERRIPIFAICRGLQELVVATGGSLHRKLCEQPELLEHREDPELPVEQQYAPSHEVL
                     VEEGGLLSALLPECSNFWVNSLHGQGAKVVSPRLRVEARSPDGLVEAVSVINHPFALG
                     VQWHPEWNSSEYALSRILFEGFITACQHHIAEKKRL"
     gene            80611..82029
                     /gene="puuA"
                     /locus_tag="IRB70_000403"
     CDS             80611..82029
                     /gene="puuA"
                     /locus_tag="IRB70_000403"
                     /EC_number="6.3.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415813.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-putrescine ligase"
                     /protein_id="HBC0630361.1"
                     /translation="METNIVEVENFVQQSEERRGSAFTQEVKRYLERYPNTQYVDVLL
                     TDLNGCFRGKRIPVSSLKKLEKGCYFPASVFAMDILGNVVEEAGLGQEMGEPDRTCVP
                     VLGSLTPSAADPEFIGQMLLTMVDEDGAPFDVEPRNVLNRLWQQLRQRGLFPVVAVEL
                     EFYLLDRQRDAEGYLQPPCAPGTDDRNTQSQVYSVDNLNHFADVLNDIDELAQLQLIP
                     ADGAVAEASPGQFEINLYHTDNVLEACDDALALKRLVRLMAEKHKMHATFMAKPYEEH
                     AGSGMHIHISMQNNRGENVLSDAEGEDSPLLKKMLAGMIDLMPSSMALLAPNVNSYRR
                     FQPGMYVPTQASWGHNNRTVALRIPCGDRHNHRVEYRVAGADANPYLVMAAIFAGILH
                     GLDNELPLQEEVEGNGLEQEGLPFPIRQSDALGEFIENDHLRRYLGERFCHVYHACKN
                     DELLQFERLITETEIEWMLKNA"
     gene            82178..82342
                     /locus_tag="IRB70_000404"
     CDS             82178..82342
                     /locus_tag="IRB70_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630362.1"
                     /translation="MPMIKSPHGEGGCVCAPPATDWTPPPLLPLLNRFDFRSTRPQTL
                     LRRGGSNYGY"
     gene            82332..83717
                     /gene="puuP"
                     /locus_tag="IRB70_000405"
     CDS             82332..83717
                     /gene="puuP"
                     /locus_tag="IRB70_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415812.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PuuP"
                     /protein_id="HBC0630363.1"
                     /translation="MAINSPLTIAAQSGKTRLRKSLKLWQVVMMGLAYLTPMTVFDTF
                     GIVSGISDGHVPASYLLALAGVLFTAISYGKLVRQFPEAGSAYTYAQKSINPHVGFMV
                     GWSSLLDYLFLPMINVLLAKIYLSALFPEVPPWVWVVTFVAILTAANLKSVNLVANFN
                     TLFVLVQISIMVVFIFLVVQGLHKGEGVGTVWSLQPFISENAHLIPIITGATIVCFSF
                     LGFDAVTTLSEETPDAARVIPKAIFLTAVYGGVIFIAASFFMQLFFPDISRFKDPDAA
                     LPEIALYVGGKLFQSIFLCTTFVNTLASGLASHASVSRLLYVMGRDNVFPERVFGYVH
                     PKWRTPALNVIMVGIVALSALFFDLVTATALINFGALVAFTFVNLSVFNHFWRRKGMN
                     KSWKDHFHYLLMPLVGALTVGVLWVNLESTSLTLGLVWASLGGAYLWYLIRRYRKVPL
                     YDGDRTPVSET"
     gene            83851..84096
                     /locus_tag="IRB70_000406"
     CDS             83851..84096
                     /locus_tag="IRB70_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmjA family protein"
                     /protein_id="HBC0630364.1"
                     /translation="MNHDIPLKYFDIADEYATECAEPVADAERTPLAHYFQLLLTRLM
                     NNEEISEEAQHEMAAEAGINPVRIDEIAEFLNQWGNE"
     gene            84409..86052
                     /gene="sapA"
                     /locus_tag="IRB70_000407"
     CDS             84409..86052
                     /gene="sapA"
                     /locus_tag="IRB70_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein SapA"
                     /protein_id="HBC0630365.1"
                     /translation="MRQVLSSLLVIAGLVSGQAIAAPESPPHADIRDSGFVYCVSGQV
                     NTFNPSKASSGLIVDTLAAQFYDRLLDVDPYTYRLMPELAESWEVLDNGATYRFHLRR
                     DVPFQKTDWFTPTRKMNADDVVFTFQRIFDRNNPWHNVNGSNFPYFDSLQFADNVKSV
                     RKLDNHTVEFRLAQPDASFLWHLATHYASVMSAEYAGKLEKEDRQEQLDRQPVGTGPY
                     QLSEYRAGQFIRLQRHDDFWRGKPLMPQVVVDLGSGGTGRLSKLLTGECDVLAWPAAS
                     QLSILRDDPRLRLTLRPGMNVAYLAFNTAKPPLNNPAVRHALALAINNQRLMQSIYYG
                     TAETAASILPRASWAYDNEAKITEYNPAKSREQLKALGLENLTLKLWVPTRSQAWNPS
                     PLKTAELIQADMAQVGVKVVIVPVEGRFQEARLMDMSHDLTLSGWATDSNDPDSFFRP
                     LLSCAAIHSQTNLAHWCDPKFDSVLRKALSSQQLAARIEAYDEAQSILAQELPILPLA
                     SSLRLQAYRYDIKGLVLSPFGNASFAGVYREKQDEVKKP"
     gene            86049..87014
                     /gene="sapB"
                     /locus_tag="IRB70_000408"
     CDS             86049..87014
                     /gene="sapB"
                     /locus_tag="IRB70_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapB"
                     /protein_id="HBC0630366.1"
                     /translation="MIIFTLRRILLLIVTLFLLTFVGFSLSYFTPHAPLQGASLWNAW
                     VFWFNGLIHWDFGVSSINGQPIAEQLKEVFPATMELCILAFGFALIVGIPVGMIAGIT
                     RHKWQDNLINAIALLGFSIPVFWLALLLTLFCSLTLGWLPVSGRFDLLYEVKPITGFA
                     LIDAWLSDSPWRDEMVMSAIRHMILPVITLSVAPTTEVIRLMRISTIEVYDQNYVKAA
                     ATRGLSRFTILRRHVLHNALPPVIPRLGLQFSTMLTLAMITEMVFSWPGLGRWLINAI
                     RQQDYAAISAGVMVCGSLVIIVNVISDILGAMANPLKHKEWYALR"
     gene            87001..87891
                     /gene="sapC"
                     /locus_tag="IRB70_000409"
     CDS             87001..87891
                     /gene="sapC"
                     /locus_tag="IRB70_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter permease SapC"
                     /protein_id="HBC0630367.1"
                     /translation="MPYDSVYSEKRPPGTLRTAWRKFYSDASAMVGLYGCAGLAVLCI
                     FGGWFAPYGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGA
                     FVVTLAATICGLVLGTFAGATHGLRSAVLNHILDTLLAIPSLLLAIIVVAFAGPSLSH
                     AMFAVWLALLPRMVRSIYSMVHDELEKEYVIAARLDGASTLNILWFAVMPNITAGLVT
                     EITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDALELIYVAPWTVMLPGAAIMIS
                     VLLVNLLGDGVRRAIIAGVE"
     gene            87891..88883
                     /gene="sapD"
                     /locus_tag="IRB70_000410"
     CDS             87891..88883
                     /gene="sapD"
                     /locus_tag="IRB70_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapD"
                     /protein_id="HBC0630368.1"
                     /translation="MPLLDIRNLTIEFKTGDEWVKAVDRVSMTLTEGEIRGLVGESGS
                     GKSLIAKAICGVNKDNWRVTADRMRFDDIDLLRLSARERRKLVGHNVSMIFQEPQSCL
                     DPSERVGRQLMQNIPAWTYKGRWWQRFGWRKRRAIELLHRVGIKDHKDAMRSFPYELT
                     EGECQKVMIAIALANQPRLLIADEPTNSMEPTTQAQIFRLLTRLNQNSNTTILLISHD
                     LQMLSQWADKINVLYCGQTVETAPSKELVTMPHHPYTQALIRAIPDFGSAMPHKSRLN
                     TLPGAIPLLEQLPIGCRLGPRCPYAQRECIVTPRLTGAKNHLYACHFPLNMEKE"
     gene            88885..89691
                     /gene="sapF"
                     /locus_tag="IRB70_000411"
     CDS             88885..89691
                     /gene="sapF"
                     /locus_tag="IRB70_000411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter ATP-binding protein
                     SapF"
                     /protein_id="HBC0630369.1"
                     /translation="MIETLLEVRNLSKTFRYRTGWFRRQTVEAVKPLSFTLREGQTLA
                     IIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHFGDYSFRSQRIRMIFQDPSTSLN
                     PRQRISQILDFPLRLNTDLEPEQRRKQIIETMRMVGLLPDHVSYYPHMLAPGQKQRLG
                     LARALILRPKVIIADEALASLDMSMRSQLINLMLELQEKQGISYIYVTQHIGMMKHIS
                     DQVLVMHQGEVVERGSTADVLASPLHELTKRLIAGHFGEALTADAWRKDR"
     gene            complement(89740..90903)
                     /locus_tag="IRB70_000412"
     CDS             complement(89740..90903)
                     /locus_tag="IRB70_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug effflux MFS transporter"
                     /protein_id="HBC0630370.1"
                     /translation="MARVSLSWALILGLLAGIGPMCTDLYLPALPEMSEQLAATTTIT
                     QLTLTASLIGLGVGQLLFGPLSDKIGRKRPLILSLLLFIVSSILCATTNNIYWLVVWR
                     FIQGIAGAGGSVLSRSIARDKYQGVTLTQFFALLMTVNGLAPVLSPVLGGYIVSTFDW
                     RTLFWVMAEISTVLLLGCLLFINETLPENKRGSSLLLTGRSVVQNRRFMRFCLIQSFM
                     LAGLFAYIGSSSFVLQKEFGFSPMQFSLVFGLNGIGLIIASWIFSRLARRINAMTLLR
                     GGLIAAILCALLTVLCAWIQLPIPALVALFFTIAFCSGIGTVGGAEAMSAVGTQESGT
                     ASALMGMSMFVFGGIAAPLSGIGGETLLKMSLAITVCYTLALLVALTRIDNQK"
     gene            complement(90912..92285)
                     /locus_tag="IRB70_000413"
     CDS             complement(90912..92285)
                     /locus_tag="IRB70_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TolC family protein"
                     /protein_id="HBC0630371.1"
                     /translation="MLRRSLIFLVLLSAGCVSLDPHYSTPESPIPATLPGAQGQGKAI
                     SHDWQQVIHDPRLQQVVTIALNSNRDVQKAIADIDSARALYGQTNASLFPTVNAALSS
                     TRSRSLANGTGTTAEADGTVSSYTLDLFGRNQSLSRAARETWLASEFTAQNTRLTLIA
                     EISTAWLTLAADNSNLALAKETMASAENSLKIIQRQQQVGTAAATDVSEAMSVYQQAR
                     ASVASYQTQVMQDKNALNLLAGTTLAENLLPGTLESLPEQMISLVPAGVSSDVLLRRP
                     DIQEAEHNLKSANADIGAARANFFPTISLTASAGVGSDALSSLFSHGMQIWSFAPSVT
                     LPLFTGGSNLAQLRYAEAQKRGLIATYEKTVQSAFKDVANALARRTTLEEQLDAQRQY
                     VKAEQQTVDVGLRRYQAGVGDYLTVLTAQRSLWSAQQELLALQLTDFTNRITLWQSLG
                     GGMSSLK"
     gene            complement(92289..95396)
                     /locus_tag="IRB70_000414"
     CDS             complement(92289..95396)
                     /locus_tag="IRB70_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HBC0630372.1"
                     /translation="MFSRFFVRRPVFAWVIAILIMLAGILAIRTLPVAQYPDVAPPTI
                     KISATYTGASAETLENSVTQVIEQQLTGLDNLLYFSSTSSSDGSVSINVTFEQGTDPD
                     TAQVQVQNKIQQAESRLPSEVQQTGVTVEKSQSNFLLIAAVYDTTDKASSSDIADWLV
                     SNVQDPLARVEGVGSLQVFGAEYAMRIWLDPAKLASYSLMPSDVQSAIEAQNVQVTAG
                     KIGALPSPDTQQLTATVRAQSRLQTVDQFKNIIVKSQSDGAVVRIKDVARVEMGSEDY
                     TAIGKLNGHPSAGVAVMLSPGANALNTATLVKDKIAEFQRNMPQGYDIAYPKDSTEFI
                     KISVEDVIQTLFEAIVLVVCVMYLFLQNLRATLIPALAVPVVLLGTFGVLALFGYSIN
                     TLTLFAMVLAIGLLVDDAIVVVENVERIMRDEGLPAREATEKSMGEISGALVAIALVL
                     SAVFLPMAFFGGSTGVIYRQFSITIISAMLLSVVVALTLTPALCGSVLQHVPPHKKGF
                     FGAFNRFYRRTEDKYQRGVIYVLRRAARTMGLYVVLGGGMALMMWKLPGSFLPTEDQG
                     EIMVQYTLPAGATAARTAEVNRQIIDWFLINEKANTDVIFTVDGFSFSGSGQNTGMAF
                     VSLKNWSQRKGAENTAQAIALRATKELGTIRDATVFAMTPPAVDGLGQSNGFTFELLA
                     NGGTDRETLLQMRNQLIEKANQSPELHSVRANDLPQMPQLQVDIDSNKAVSLGLSLND
                     VTDTLSSAWGGTYVNDFIDRGRVKKVYIQGDSEFRSAPSDLGKWFVRGSDNAMTPFSA
                     FATTRWLYGPERLVRYNGSAAYEIQGENATGFSSGDAMTKMEELANSLPAGTTWAWSG
                     LSLQEKLASGQALSLYAVSILVVFLCLAALYESWSVPFSVILVIPLGLLGAALAAWMR
                     DLNNDVYFQVALLTTIGLSSKNAILIVEFAEAAVAEGYSLSRAALRAAQTRLRPIIMT
                     SLAFIAGVMPLAIATGAGANSRIAIGTGIIGGTLTATLLAIFFVPLFFVLVKRLFAGK
                     PRRQE"
     gene            complement(95396..96517)
                     /locus_tag="IRB70_000415"
     CDS             complement(95396..96517)
                     /locus_tag="IRB70_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter periplasmic adaptor
                     subunit"
                     /protein_id="HBC0630373.1"
                     /translation="MKYIATSVVAMLLLSGCDNTQSNNSSPSETEVGVVTLKSQPVSV
                     VSELTGRTSAALSAEVRPQVGGIIQKRLFKEGDLVKAGQPLYQIDAASYQAAWNEARA
                     ALQQAQALVKADCQKAQRYARLVKENGVSQQDADDAQSTCAQDKASVEAKKAALETAR
                     INLDWTTVTAPISGRIGISSVTPGALVTASQDTALTTIRGLDTMYVDLTRSSVDLLRL
                     RKQSLATNSDTMSVSLILEDGTTYSEKGRLELTEVAVDESTGSVTLRAIFPNPQQQLL
                     PGMFVRARVDEGVMENAILAPQQGVTRDAKGNATALVVNKDNKVEQRTLETGETYGDK
                     WLVLNGLHNGDRLIVEGSAKVTSGQTVKAVEVQANGGNA"
     gene            complement(96666..97232)
                     /locus_tag="IRB70_000416"
     CDS             complement(96666..97232)
                     /locus_tag="IRB70_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBC0630374.1"
                     /translation="MTSKLEIRHKQRQDEIINAARRCFRRCGFHAASMSQIASEAQLS
                     VGQIYRYFANKDAIIEEMVRRIIDFRIAQMDIDARTDHFPEVLALRKSLNEDDDALML
                     EVAAEATRNPRVMAMLEEADARMFANGCAHMKRMHPHLSDEHIRCCVEVFATMMEGTV
                     YRRLTPQKSDPQHLQEIYQDIVSMLINK"
     gene            97710..98498
                     /gene="fabI"
                     /locus_tag="IRB70_000417"
     CDS             97710..98498
                     /gene="fabI"
                     /locus_tag="IRB70_000417"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBC0630375.1"
                     /translation="MGFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKL
                     KGRVEEFAAQLGSDIVLQCDVAEDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDG
                     DYVNAVTREGFKIAHDISSYSFVAMAKACRSMLNPGSALLTLSYLGAERAIPNYNVMG
                     LAKASLEANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRKMLAHCEAVTPIRR
                     TVTIEDVGNSAAFLCSDLSAGISGEVVHVDGGFSIAAMNELELK"
     gene            98642..99757
                     /locus_tag="IRB70_000418"
     CDS             98642..99757
                     /locus_tag="IRB70_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707196.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CMD domain-containing protein"
                     /protein_id="HBC0630376.1"
                     /translation="MEQRHITGKSHWYHETQSSTAEYDVLPLVPEAAKVSDPFLLDVI
                     LDEETLAPFLSWLVPARVLAVELFPDQLTVTRSQTFTAYERLSTALTVAQVCGVQRLC
                     NYYSARLTPLPGPDSSRESNHRLAQITQYARQLASSPSIIDNRSRQHLNDVGLTAWDC
                     VIINQIIGFIGFQARSIATFQAYLGHPVRWLPGLEIQNYADASLFADESIRWRSSYEV
                     EKLPEEHTKSSTAELCQLAETLSLHPISLSLLEKLLNSTRVNTQPDNQLAALLCARIN
                     GSPACFATCMDSSNEYKKISAGENEINQWADRHSVERATVQAIQWLTRAPDRFSAAQF
                     SPLLEHEKSSTQIINLLVWSGLCGWINRLKIALGETY"
     gene            99825..101759
                     /gene="rnb"
                     /locus_tag="IRB70_000419"
     CDS             99825..101759
                     /gene="rnb"
                     /locus_tag="IRB70_000419"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exoribonuclease II"
                     /protein_id="HBC0630377.1"
                     /translation="MFQDNPLLAQLKQQLHSQTPRAEGVVKATEKGFGFLEVDAQKSY
                     FIPPPQMKKVMHGDRIIAVIHSEKERESAEPEELVEPFLTRFVGKVQGKNDRLAIVPD
                     HPLLKDAIPCRAARGLNHEFKEGDWAVAEMRRHPLKGDRSFYAELTQYITFGDDHFVP
                     WWVTLARHNLEKEAPDGVATEMLDEGLVREDLTALDFVTIDSASTEDMDDALFAKALP
                     DDKLQLIVAIADPTAWIAEGSKLDKAAKIRAFTNYLPGFNIPMLPRELSDDLCSLRAN
                     EVRPVLACRMTLSADGTIEDNIEFFAATIESKAKLVYDQVSDWLENTGDWQPESEAIA
                     EQVRLLAQICQRRGEWRHNHALVFKDRPDYRFILGEKGEVLDIVAEPRRIANRIVEEA
                     MIAANICAARVLRDKLGFGIYNVHMGFDPANADALAALLKTHGLHVDAEEVLTLDGFC
                     KLRRELDAQPTGFLDSRIRRFQSFAEISTEPGPHFGLGLEAYATWTSPIRKYGDMINH
                     RLLKAVIKGETATRPQDEITVQMAERRRLNRMAERDVGDWLYARFLKDKAGTDTRFAA
                     EIVDISRGGMRVRLVDNGAIAFIPAPFLHAVRDELVCSQENGTVQIKGETAYKVTDVI
                     DVTIAEVRMETRSIIARPVA"
     gene            complement(101837..101941)
                     /locus_tag="IRB70_000420"
     CDS             complement(101837..101941)
                     /locus_tag="IRB70_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630378.1"
                     /translation="MTYMKLTAAKRIVFFIYLFVIQFWKNASFQTKVS"
     gene            101995..103980
                     /gene="pdeR"
                     /locus_tag="IRB70_000421"
     CDS             101995..103980
                     /gene="pdeR"
                     /locus_tag="IRB70_000421"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HBC0630379.1"
                     /translation="MKTVRESTTLYNFLGSHNPYWRLTESSDVLRFSTTETTEPDRTL
                     QLSAEQAARIREMTVITSSLMMSLTVDESDLSVHLVGRKINKREWAGNASAWHDTPAV
                     ARDLSHGLSFAEQVVSEAHSAIVILDSRGNIQRFNRLCEDYTGLKEHDVIGQSVFKLF
                     MSRREAAASRRNNRVFFRSGNAYEVELWIPTRKGQRLFLFRNKFVHSGSGKNEIFLIC
                     SGTDITEERRAQERLRILANTDSITGLPNRNAMQELIDHAINQADNNKVGVVYLDLDN
                     FKKVNDAYGHLFGDQLLRDVSLAILSCLEHDQVLARPGGDEFLVLASNTSQSALEAMA
                     SRILTRLRLPFRIGLIEVYTSCSVGISLSPEHGSDSAAIIRHADTAMYTAKEGGRGQF
                     CVFTPEMNQRVFEYLWLDTNLRKALENDQLVIHYQPKITWRGEVRSLEALVRWQSPER
                     GLIPPLDFISYAEESGLIVPLGRWVILDVVRQVAKWRDKGINLRVAVNISARQLADQT
                     IFTALKQVLQELNFEYCPIDVELTESCLIENDELALSVIQQFSQLGAQVHLDDFGTGY
                     SSLSQLARFPIDAIKLDQVFVRDIHKQPVSQSLVRAIVAVAQALNLQVIAEGVESKKE
                     DAFLTKNGINERQGFLFAKPMPAVAFERWYKRYLKRA"
     gene            104127..104300
                     /locus_tag="IRB70_000422"
     CDS             104127..104300
                     /locus_tag="IRB70_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630380.1"
                     /translation="MSEFDAQRVAERIDIVLDILVAGDYHSAVHNLEILKAELLRQVA
                     ESTPDIPKAPWEI"
     gene            104390..105139
                     /locus_tag="IRB70_000423"
     CDS             104390..105139
                     /locus_tag="IRB70_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBC0630381.1"
                     /translation="MNSRQQTILQMVIDQGQVSVTDLAKATGVSEVTIRQDLNTLEKL
                     SYLRRAHGFAVSLDSDDVETRMMSNYTLKRELAEFAASLVQPGETIFIENGSSNALLA
                     RTLGEQKKNVTIITVSSYIAHLLKDAPCEVILLGGVYQKKSESMVGPLTRQCIQQVHF
                     SKAFIGIDGWQPETGFTGRDMMRTDVVNAVLEKECEAIVLTDSSKFGAVHSYSIGPVE
                     RFNRVITDSKIRASDLMHLEHSKLTVHVVDI"
     gene            105408..105626
                     /gene="osmB"
                     /locus_tag="IRB70_000424"
     CDS             105408..105626
                     /gene="osmB"
                     /locus_tag="IRB70_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmB"
                     /protein_id="HBC0630382.1"
                     /translation="MFVTSKKMTAAVLAITLAMSLSACSNWSKRDRNTAIGAGAGALG
                     GAVLTDGSTLGTLGGAAIGGVIGHQVGK"
     gene            complement(105752..106078)
                     /gene="yciH"
                     /locus_tag="IRB70_000425"
     CDS             complement(105752..106078)
                     /gene="yciH"
                     /locus_tag="IRB70_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415798.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response translation initiation inhibitor
                     YciH"
                     /protein_id="HBC0630383.1"
                     /translation="MSDSNSRLVYSTETGRIDEPKAAPVRPKGDGVVRIQRQTSGRKG
                     KGVCLITGVDLDDAELTKLAAELKKKCGCGGAVKDGIIEIQGDKRDLLKSLLEAKGMK
                     VKLAGG"
     gene            complement(106078..106815)
                     /gene="pyrF"
                     /locus_tag="IRB70_000426"
     CDS             complement(106078..106815)
                     /gene="pyrF"
                     /locus_tag="IRB70_000426"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBC0630384.1"
                     /translation="MTLTASSSSRAVTNSPVVVALDYHNRDAALAFVDKIDPRDCRLK
                     VGKEMFTLFGPQFVRELQQRGFDIFLDLKFHDIPNTAAHAVAAAADLGVWMVNVHASG
                     GARMMTAAREALVPFGKDAPLLIAVTVLTSMEASDLADLGVTLSPADYAERLAALTQK
                     CGLDGVVCSAQEAVRFKQVFGQAFKLVTPGIRPQGSEAGDQRRIMTPEQALAAGVDYM
                     VIGRPVTQSVDPAQTLKAINASLQRSA"
     gene            complement(107007..108176)
                     /gene="lapB"
                     /locus_tag="IRB70_000427"
     CDS             complement(107007..108176)
                     /gene="lapB"
                     /locus_tag="IRB70_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapB"
                     /protein_id="HBC0630385.1"
                     /translation="MLELLFLLLPVAAAYGWYMGRRSAQQNKQDEANRLSRDYVAGVN
                     FLLSNQQDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLT
                     YEQRLLAIQQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKA
                     IDVAERLVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSI
                     MMGRVFMAKGEYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAV
                     EENTGADAELMLADIIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEAEEGRA
                     KESLMVLRDMVGEKVRSKPRYRCQKCGFTAYTLYWHCPSCRAWSTIKPIRGLDGL"
     gene            complement(108183..108491)
                     /gene="lapA"
                     /locus_tag="IRB70_000428"
     CDS             complement(108183..108491)
                     /gene="lapA"
                     /locus_tag="IRB70_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide assembly protein LapA"
                     /protein_id="HBC0630386.1"
                     /translation="MKYLLIFLLVLAIFVISVTLGAQNDQQVTFNYLLAQGEYRISTL
                     LAVLFAAGFAIGWLICGLFWLRVRVSLARAERKIKRLENQLSPATDVAVAPHSSASKE
                     "
     gene            complement(108640..109404)
                     /gene="pgpB"
                     /locus_tag="IRB70_000429"
     CDS             complement(108640..109404)
                     /gene="pgpB"
                     /locus_tag="IRB70_000429"
                     /EC_number="3.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase B"
                     /protein_id="HBC0630387.1"
                     /translation="MRSIARRTAVGTALLLVMPVAVWISGWRWQPGEQSWLLKAAFWV
                     TETVTQPWGVITHLILFGWFLWCLRFRIKAAIMLFAILAAAILVGQGVKSWIKDKVQE
                     PRPFVIWLEKTHHIPVDEFYTLKRAERGNLVKEQLAEEKNIPQYLRSHWQKETGFAFP
                     SGHTMFAASWALLAVGLLWPRRRTLTIAILLVWATGVMGSRLLLGMHWPRDLVVATLI
                     SWALVAVATWLAQRICGPLTPPAEENREIAQREQES"
     gene            109574..110164
                     /gene="ribA"
                     /locus_tag="IRB70_000430"
     CDS             109574..110164
                     /gene="ribA"
                     /locus_tag="IRB70_000430"
                     /EC_number="3.5.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase II"
                     /protein_id="HBC0630388.1"
                     /translation="MQLKRVAEAKLPTPWGDFLMVGFEELATGHDHVALVYGDISGHT
                     PVLARVHSECLTGDALFSLRCDCGFQLEAALTQIAEEGRGILLYHRQEGRNIGLLNKI
                     RAYALQDQGYDTVEANHQLGFAADERDFTLCADMFKLLGVNEVRLLTNNPKKVEILTE
                     AGINIVERVPLIVGRNPNNEHYLDTKAEKMGHLLNK"
     gene            complement(110228..112903)
                     /gene="acnA"
                     /locus_tag="IRB70_000431"
     CDS             complement(110228..112903)
                     /gene="acnA"
                     /locus_tag="IRB70_000431"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aconitate hydratase AcnA"
                     /protein_id="HBC0630389.1"
                     /translation="MSSTLREASKDTLQAKDKTYHYYSLPLAAKSLGDITRLPKSLKV
                     LLENLLRWQDGNSVTEEDIYALAGWLKNAHADREIAYRPARVLMQDFTGVPAVVDLAA
                     MREAVKRLGGDTAKVNPLSPVDLVIDHSVTVDRFGDDEAFEENVRLEMERNHERYVFL
                     KWGKQAFSRFSVVPPGTGICHQVNLEYLGKAVWSELQDGEWIAYPDTLVGTDSHTTMI
                     NGLGVLGWGVGGIEAEAAMLGQPVSMLIPDVVGFKLTGKLREGITATDLVLTVTQMLR
                     KHGVVGKFVEFYGDGLDSLPLADRATIANMSPEYGATCGFFPIDAVTLDYMRLSGRSE
                     DQVELVEKYAKAQGMWRNPGDEPIFTSTLELDMNDVEASLAGPKRPQDRVALPDVPKA
                     FAASNELEVNATHKDRQPVDYVMNGHQYQLPDGAVVIAAITSCTNTSNPSVLMAAGLL
                     AKKAVTLGLKRQPWVKASLAPGSKVVSDYLAKAKLTPYLDELGFNLVGYGCTTCIGNS
                     GPLPDPIETAIKKGDLTVGAVLSGNRNFEGRIHPLVKTNWLASPPLVVAYALAGNMNI
                     NLASEPIGHDRKGDPVYLKDIWPSAQEIARAVEQVSTEMFRKEYAEVFEGTAEWKEIN
                     VARSDTYGWQEDSTYIRLSPFFDEMQATPAPVEDIHGARILAMLGDSVTTDHISPAGS
                     IKPDSPAGRYLQGRGVERKDFNSYGSRRGNHEVMMRGTFANIRIRNEMVPGVEGGMTR
                     HLPDSDVVSIYDAAMRYKQEQTPLAVIAGKEYGSGSSRDWAAKGPRLLGIRVVIAESF
                     ERIHRSNLIGMGILPLEFPQGVTRKTLGLTGEEKIDIGDLQNLQPGATVPVTLTRADG
                     SQEVVPCRCRIDTATELTYYQNDGILHYVIRNMLK"
     gene            complement(113068..113163)
                     /locus_tag="IRB70_000432"
     CDS             complement(113068..113163)
                     /locus_tag="IRB70_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630390.1"
                     /translation="MINTNMKYWSWMGAFSLSMLFWAELLWIITH"
     gene            complement(113277..113444)
                     /locus_tag="IRB70_000433"
     CDS             complement(113277..113444)
                     /locus_tag="IRB70_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_304581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630391.1"
                     /translation="MVGQEQLESSPLCQHSDNEPETKRECSVVIPDDWQLTSQQQAFI
                     ELFAEDDQPKQ"
     gene            complement(113447..113611)
                     /locus_tag="IRB70_000434"
     CDS             complement(113447..113611)
                     /locus_tag="IRB70_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmiA family putative membrane protein"
                     /protein_id="HBC0630392.1"
                     /translation="MLISDGDYMRLAMPSGNQEPRRDPELKRKAWLAVFLGSALFWVV
                     IALLIWKVWG"
BASE COUNT        28078 a        29855 c        27531 g        28294 t
ORIGIN      
        1 caaacaactt cacttgtcag cgacaccgct tcgtttttaa catcgcttat ggaaaaaaat
       61 agtctgttta gtcagcgcat ccgtttgcgc caccttcata cattcgtagc tgtcgcacaa
      121 caaggaactt tggggcgcgc ggctgaaacc cttaatttga gtcaacctgc gctctctaag
      181 acattgaatg aactggagca gctgacgggc gctcgcttgt ttgagcgtgg tcgtcagggg
      241 gcgcaactta ccttacccgg cgaacaattt ttaacgcatg cagtcagagt tcttgacgcc
      301 atcaacactg ctggacagtc gcttcatcgt aaagaaggtc ttaataatga tgtcgtcagg
      361 gttggtgcac taccgactgc ggcactgggg atattacctt cggttatagg tcagtttcat
      421 cagcaacaaa aagagacgac cttgcaagtt gcgacaatga gtaaccctat gattcttgcg
      481 ggtttaaaaa ccggggaaat cgatatcggc attggtcgga tgtcagatcc tgaactgatg
      541 accggactta attacgaact gctgtttctt gaatcgctga agctggttgt ccgccctaat
      601 catccgctac ttcaggagaa cgtaacgcta agccgggtgc tggaatggcc ggtcgttgta
      661 tcaccagaag gcactgcgcc acgccagcat tcagatgcat tagtgcagag ccagggctgt
      721 aaaattcctt cgggctgtat cgaaacactg tctgcttcgc tatctcgtca acttacggtt
      781 gaatacgact acgtgtggtt tgtcccttct ggcgctgtaa aagacgacct gcgtcatgcc
      841 acgctggtgg ccctgcctgt tccgggacat ggtgcaggcg aaccgattgg aatactgacc
      901 cgcgtagatg cgacgttctc ttctggttgc cagttgatga ttaacgctat tcgaaaatca
      961 atgccgttct gaaaggtgaa gggatctgtc gatcccttcc ttgaacattt tcacaccgta
     1021 gcgaaactaa ctgattcacc cgctccgcga ggttctgccg acacagaatg tttgttcaga
     1081 cggaatacgt ccaccgcctc agttaatcgt gccgcctgtt cttcaaggga caccgccgcc
     1141 gctgaggcct cttctaccag agaagcattc tgttgcgtca ccttatccat ttctgaaatc
     1201 gcctggctaa cctgcgttat gcctctgctt tgttcatccg aggcggcggc aatttcctgc
     1261 atgatatgtg tgacactcgc gacggcatca acaatagtgc tcatggtttt ccctgccgtt
     1321 gccacctcat ccgatcccag gtcaattaat ctgactgatt cactgatcaa gccttcaatc
     1381 tctttcgccg cctgagcgct gcggcttgcg agtgtccgta cttcgctggc gacaacggca
     1441 aatccacgtc cttgctcacc cgctcgcgcg gcttcaacgg cagcattcag tgccagaata
     1501 ttcgtctgga aagcaatact gttgatgacg gcggtgatct cagaaatttt cttcgaactc
     1561 gtggagatag cgcccatcgt ttttactaca ccggaaaccg tctgcccgcc atcgctggct
     1621 ttaatagaag cctcctgcgc cagtttgctg gcatgatgcg cgttatctgc attctgtttc
     1681 accgtcgcag tgagttgctc catgctggcg gcagtttgtt caattgccgc cgcttgttct
     1741 tcggtgcgag atgaaaggtc cgcattgcca gcggaaattt cgctggtgcc acgataaatc
     1801 tcttccgcgc cctgtcgaac ggtccctaca gtcatcccca gtgaatgctg catttgctgt
     1861 aaatgacgac ttaagcgacc gatttcatta cgacccgccg gttcatcatt catcgtcaga
     1921 tcgccactgg cgattttttc aatccgttgt gcggcatgtt gcagtggacg aatgacgatc
     1981 cgacgtagca ctataaatgt tatcagcgtc atgaccaggg caagcacaaa cgcgccaatc
     2041 atgaacatcc cacccaggcg ggtgcgctga tgggccagtt ccgccagttg gttggctctg
     2101 gtgctacgta tcttaacggc tttgttcaaa atatcggtat aagcattatc cagcggtcgg
     2161 atctgctcac tttcatgatt gataatcgct tcaaacatgc catttttggc atatttcaac
     2221 atcggttgca tacccgtgat ataagcctgg aagcgttgat ttaattcagt gtcgagggct
     2281 tcatcagcag gtgttttcac cgaccgattc tgataagcac gataaccttg ctgcgactgt
     2341 ttaatctccg attcggcttg cgcaatattt cgcttcattg cttccatttc cgcaatacga
     2401 ctcgcagcac cggcctgaat catattgatc cgggctgaac gcaaaaaatc tgaactgttc
     2461 gctaacccgg tccgaatctc aatctccgca gtaacatcac gctgatcgcg atcggcctgc
     2521 cagaggaaat agccagccag agcagaactt aatgctaata gaactaagat accgccaaga
     2581 atgcaggcaa ataacggaac cagcctgatg tgatgcaaaa aacctaatcg ctgtgaggga
     2641 gttgtattca ttaccgttgt ctctcgtcca ggtttactcc tgatagaaag tcatcggcac
     2701 ttgacggtaa ttacttatga ccaaaaacct ctttgcgtca catttttaca acaattatgg
     2761 cagagaagaa taatgccatt ggaatgaaga gagtaacgaa cggctaaacc gaatgacgaa
     2821 aaattctgga aaacagcacg caatttcgtc aagtgattat tttcgtccct aaggaaacct
     2881 cataggatgc ctgcgggtgc ctgagacttt ctgttttcag gctaaccggg aatcagaaag
     2941 acgaaggccc cgaccgatat ttctatcaac tgtactgcac ccattttgtt agcctcttac
     3001 ccgccatccg gcaaggagaa aggctatgaa gcgcaaccct ctggtggtgt gtctgctcat
     3061 tatctgcatt acgattctga cattcacact cctgacccga caaacgctct acgaactgcg
     3121 gttccgggac ggtgataagg aggttgctgc gctcatggcc tgcacgtcca ggtaagggca
     3181 agcgcgggga ttttccccgc gcatctgact agcagattca ttttctcatg gcaccccttt
     3241 tacacttcag ttagtgcatg tttttttcga tgcactaata gaaccatcat tacagacaaa
     3301 tttgccgcct gccgtacagt gtgagatccc ccctttcgaa ccagaacagg gtttgcgccc
     3361 ggcatcggca taaaaggaaa caagcgctcc taaaaccaag ataagtgcca gttttttcat
     3421 ataacctcca tggtttatcg aatcttatgt tcgatttgaa cgttatacgc tggtttattt
     3481 tgataccgtt gatgagatca aagatcgggt gaattgatta aagataagcc agatggacgt
     3541 atggaccagg attatggttt tatttgtcat acaaataaat ataataggcg cttccgatgt
     3601 agacccgtat tcttcgcctg taccacgggt cggttttagt acaggcgttt tctttaaata
     3661 tccttcagga acgtttacgc ggcatcatgc gtagaagtgt gttgtccttc cagaaatagt
     3721 ggtgtgccag tgcagccgca gcgtgcaacc cgatgacaaa gtatcccaga ttcgccagcg
     3781 tttcatgcca cgactttaag ctatcaaccc gttcgaaatt ggcctctgat gcataaggca
     3841 tcgtcatacc aaacgcaaac cacgggttac cccggttata catcatcacc aaaccaatca
     3901 ctggcagcgc aataaacagg agatagatca ccaaatgtcc caaatgcgcc agtcccgtca
     3961 tcatcggttt tggcttaggt ataatcggcg gggttgggta tttcagcctt aacaaaagac
     4021 gaaccaccat cagtacgaga attgagatgc cacaggaaac atgaatcatg ttgatgaggg
     4081 gccgatcgct acgtgggaag aaaccacgaa actccattgc gcaatacgct acgataacca
     4141 gcaaaaagac cagccagtga atgctgattt gtaaccttga gtatttattt cccataacat
     4201 ttcctgcttt aacataattt tccgttaaca taacgggctt ttcttaaaat ttcattaaat
     4261 attgttcacc cgttttcagt acgttacgtt tcactgcaag aatgtagatt gcccatcccg
     4321 ccatcctggt ctaagcctgg aaaggatcaa ttttcatccg aacgttcctg acaggagaag
     4381 accatgagta aagttggtat taacggtttt ggtcgtatcg gtcgactggt gttgcgtcga
     4441 ttacttgaag tcaaaagcaa catagacatt gtcgctatta atgatctcac ttccccaaaa
     4501 attctcgcct acctgctgaa acatgattca aactacggac cgttcccctg gagcgttgat
     4561 tttacggaag attcacttat cgttgatggg aaaagtatcg cggtttacgc cgaaaaagag
     4621 gctaaaaata ttccgtggaa agcgaaaggc gcagaaatca ttgtcgaatg tactggcttt
     4681 tatacctccg ccgagaaatc tcaggcgcat ctcgatgctg gcgcgaagaa ggtgttgatt
     4741 tccgcccctg ccggtgaaat gaaaactatc gtttataacg tcaatgacga cactctggat
     4801 gcaacgacac cattgtttcc gtggcatcct gtaccactaa ctgtcttgct ccgatggcaa
     4861 aagccttgca tgacagtttc ggaatagaag tcggcacgat gacgaccatt catgcctata
     4921 ccggcactca gtcactggtg gatggtccgc gaggtaaaga tttacgcgct tcacgtgcag
     4981 cggcagaaaa tatcattccc cacactacag gtgcggcaaa agccattggt ctggtgatcc
     5041 ccgaacttag cggcaaactt aaaggccatg cgcaacgcgt gccagtgaaa acaggttcag
     5101 tgaccgagct ggtgtctatc ctggggaaaa aagtgactgc tgaagaggtg aataacgcac
     5161 ttaaaaaagc aacaaccgat aacgaatcgt ttggttatac cgacgaagaa attgtctctt
     5221 ccgatatcat tggcagccat ttcggttcgg tgtttgatgc gacccaaacg gaaatcaccg
     5281 cagtgggcga tttacaactg gtgaagaccg tcgcctggta cgataacgag tatggtttcg
     5341 tcactcaact cattcgtacc ctggaaaaat tcgccaaact ctgaccagca caggcggagg
     5401 aaaaacctcc gcctctttca ttcattacga ctgtaaataa accacctggg tctgcaggta
     5461 ttcatgcaag ccatgtttgc catctgcgcc gccaataccg gatttacgcc atccggcgtg
     5521 gaagccttgc atagcttcga agttttcacg gttgatgtaa gtttcaccaa acttcagccc
     5581 tttaatggct ttcatcgcga cgttcagatt ttgggtatag attgatgagg tcaggccgta
     5641 atcactatca ttcgccattg agatagcctc ttccagcgtg tcaaatgcga ccaccggcag
     5701 aaccgggcca aaggtttcct catgcataat cgacatttcc tggcgaacat ccagcagcaa
     5761 tgtcggcgga taataatatc ctttcccctc tactgccttg ccccccaacg ccactctcgc
     5821 cccttcttct actgcgcgcg ccactttttg ctcgaccctt tccagcgccg cggcgttaat
     5881 caacggcccc atcgcaatgt cgttgcgttc agcggggtta ccaaattgaa ccgcttgcat
     5941 cgcttcaccc aaccgattga caaactgatc ataaatgcct ttctgtacat aaacacgttc
     6001 tgcacagtta cacacttgcc cactattaat gacgcgtgaa tcaacgatgg ctttgactgc
     6061 cagttcaaga tcggcatcgt ccattacgat agccggtgct ttacccccca gttccaggca
     6121 cactttggtg atgtttttcg ccgcagtcgc cataatcttt tcacctgcag agacgctgcc
     6181 tgtcatactg accattgcga cctttgggtt acctgccagt tcttgcccaa cggtttcacc
     6241 acgccccaga acaaggttaa acacgccgcg cggaaggcct atttcatcga cgattttggc
     6301 gaatgcaatc gcattgtttg gcgtaaattc actgggttta atgacgatgg tattaccggt
     6361 caaaagagcg ggagccattt tgcgggcaat gaggaagaac gggaagttcc acggcagaat
     6421 gccggtagtc acgccaagcg cacgtttaaa cagaagaata ttttctcctg gacgatcgct
     6481 ttgaataatc tcgccttcat aacgccgtgc ccactccgac atgtaatcga tatagtccgc
     6541 agtaaaagcc acttcgactt cagccagccg ctggatctta cccccttctt caacaatcag
     6601 cgcactgatt tcactggcgc gttcgcggat cccggcggag attttgcgca accaactggc
     6661 gcgttcaata gcaggcaacg cttcccattc tggttgtgca cgttctgctg catcgattgc
     6721 cttacgggca tcctcggcct gaccatcggg aatgcgggaa atgacagcct ctgtagcagg
     6781 gtttaccaca tcaatccatg cgtctccacg ccaggtaaca aactgtccat caatatacat
     6841 aggatgttga acgggtactg acatgagcga ctcctgtgat ttatatgttt gtttttggta
     6901 aatacattgt taattaacat caatcatcag agagacggca tcatgaaagg acaattctgt
     6961 gaagggcttc ataaaaacaa gtgtaaaagg aataagaggc agaaataaaa ggcaggagtt
     7021 atgcccgttt gcaaacaagt ggttcacaaa cgggcaattt ttaacgtaac gagcgacttt
     7081 ccatcgcctc gatgagcacc gcatcgtgtt tcagcgtttg ccatgcctga atgacttctg
     7141 caggaaaatc aacgtgaacg ataaaatctc gcccgcgggg gccgtagcca tcgctatcat
     7201 cgtgtaaacg cggcagctcg ccagtgagta gtgatagata acgctcaacc ggccataatc
     7261 cttgtaactg attaataaag attacactgt ctgcgttatt tcctaactga ggaacgaatc
     7321 cgggataact taaccagcgt ggtgcatcgg gattgtcccc ggtcatacgg cggaacgtcg
     7381 ccatcgtgcg ccgctgcatg gtggggtcct gaacaacgat agctgtgtga actcgttcta
     7441 cggcctgatt caatagcgcg atgctaaagc gtgcgttttc accgcagttt gttgactggt
     7501 cttcaatcca gattttttca tgcggaatgt gccagaactg atgagcgata tccgccagaa
     7561 tggtagcttc tgctctgcca gtggtgcgga tagtgttgta gtgcggatgc tgtgcgatgg
     7621 cgctatacaa aaaagttgtc gagtgaccga taccaccact aatcagtaaa ggaatttgct
     7681 gatcgcgggc aatcttacat gccgcatcga tagtcggcat aaccgcattg cctgcaagga
     7741 tcacgcaatc ggcctgatac ggcacctcac cggagaaatc atcctgcgcc agccactgtc
     7801 cgataacatt tatggcatct atggttgccg gcgaaagcgt cggaaacggg gtaatgttca
     7861 tggttcctcc ttatcgttcc cttaagaata ctgcgtgaga taatagtgag aagcggagca
     7921 ctctgaaagg aggaagtcgt atttccttaa ccgccactcc gcaagcctga catatctttt
     7981 aaggaaatgc tgtagataaa cattattcat cttgcagcag agaattgtat ttttctgaac
     8041 tcctgaattt tttcccatac cgtttttaga attaataaaa aacccggcgc taaatgctta
     8101 ccgggtttta gatttatcag gcaaatagca gtgttaaccg ctaatctgct ccatcgcctg
     8161 caaaatacgc ttatctgaaa tcggataagg cgtaccaagt tgttgagcga agtaactaac
     8221 gcgcaactct tctatcatcc aacggatctc tttcacgtct tcatcctcac gacgtgcggg
     8281 cggcagttta ttgatccatt gctgccacgc ctgctggaca ttttcgactt tcagcatctg
     8341 agcacggtcg cgatgtgggt caaccgccag tttttccagc cgtttttcaa tcgcctgcaa
     8401 ataacgcagc gtgtcgccca accgtttgaa gccgttacca gtcacaaaac cgcgatacac
     8461 cagcccgccc atctgcgctt taatgtcaga aagccccagc gccatggtca tatccacccg
     8521 ccctttcaga cgtttgttga tattgaacac tgccgtaaga atttgctcga cctgcttcgc
     8581 aatatccacc accgtgtcgt tcagttcggc acgcactttc tcatgcagcg cagcaaagcc
     8641 ttcttccgtc cagaccgggc caccattggc gtcgatcagt tgatccaccc cgcaggagat
     8701 acagtcgtcg atcagctcca gcactttgcc atacgggtta aagtacagcc ccagcttggc
     8761 tttgttcggt aacttttcat gcaaatactt gatcggcgat ggaatattca gcagcagtag
     8821 acggcgaaga ccgttccaca ttgcctgctt ttgttccagc ggattatcaa acagtttgat
     8881 cgccacgctg tcgcgttcat ccaccagcgc cggccacgcc ttcactttgt agttgccgcg
     8941 cttctgctcg tagctttccg gcagctgacc aaaactccag atatgtaagc cgctctgctc
     9001 gataccgtca tccgccacgg cagacagcgt ttcctgcact ttgcctttca gggcgtcttt
     9061 cagatcctgt aatgagcgcc cttcttttag cttcttgttt ttttcatcca ccacgcggaa
     9121 ggtgattttc aggtgatcgg gcacctgatc ccagtgccag tcttcgcggt caacggtgac
     9181 gccagtcatc cgccgtaact cgcgctcaag gctgtcgagc aacggtaact ccagcggtgt
     9241 gacgcggcct aaaaacgctt ctgcgtagtt tggtgcaggc acaaaattac ggcgtaccgg
     9301 tttcggcaac gatttaatca gagcaatcac cagttcgcgg cgcaggccgg ggatttgcca
     9361 ttcaaacccg ctctcttcta cctgattaag cagcggcagc gggatatgca cagtcacacc
     9421 gtcagcatcc gcgccgggct caaactgata gctcaaacgc agcttgagat tgccctgatg
     9481 ccagaagttc ggataatcca gcttgctgat tttttccgcc ccttctttga tcaacatgct
     9541 cttttcaaag ttgagcaaat caggcgtttc gcggctgact tttttccacc agctatcgaa
     9601 gtgacgagcg gagattacat cgtggctgat gcgctggtcg tagaactcaa acagcgtttc
     9661 gtcatcaacc agaatatcgc ggcgacgtga tttgtgttcc agctcttcca cttcggcccg
     9721 cagtttcagg ttttcacgga agaatgcgtg acgcgtctgc cagtcacctt ccaccagagc
     9781 gtggcgaata aagagttcac gacataacgc cggatcgatc tggctgtagt tgaccttacg
     9841 cgcagcaaca atcggcaaac cataaacagt gactttttcc gttgccatca ccgcgccctg
     9901 cgcccgttcc cagtgcggtt cgctgtaggt gcgtttaatc aaatgctgag caacgggttc
     9961 tacccattcc gggtcgatac gcgcagcaat gcgcccccac aggcggctgg tttctaccag
    10021 ttccgccacc attacccatt tcggcggctt tttaaataag ccggaaccgg ggaaaatgga
    10081 gaaacgcgcg ttacgtgcgc cggtatattc ttgtttatcg gcatctttca tgccgatatg
    10141 ggaaagtaaa cccgtcagca acgcaatgtg aatttcacga tactccgccg gttcgctgtt
    10201 aaccggaatg ccaagttctt tcaccacctg gcgcaactgg gtgtagatat cctgccattc
    10261 gcgcacgcgc agatagttga gataatcggt acgacacagg cgacggaagg cgttggaaga
    10321 aagcgccttt tgctgctcgc caagataatt ccacagattt acaaacgcga ggaagtcgga
    10381 ttctttgtcg tggaagcggc gatgtttttc gtccgatgcc tgctgtttat ccatcggacg
    10441 ctcgcgcgga tcctgaatgg agagcgcgga cgtgataatc atcgcctcac gcacgcagcc
    10501 atgtttttgc gcttccagca ccatacgcgc cagacgtggg tcgacaggca actgcgagag
    10561 ctggcgaccg agcggcgtca gtttataggc gctggcctgt tcatccgtgg tgatcgcgcc
    10621 cagttcttcg agcagacgca cgccatcctg gatattgcgt ttatccggtg cttcaacaaa
    10681 cgggaacgca gcgatatcgc ccagccccag cgcagtcatc tgcaaaataa ccgaggccag
    10741 gttggtacgc agaatctccg gatcggtaaa ttccgggcgc gaaaggaaat cgtcttcgga
    10801 atagagacga atacagatcc cttcggacac acgaccacag cggcctttac gctgattggc
    10861 agacgcctgc gaaatgggtt caatcggcaa acgctgcact ttggtgcgat agctgtagcg
    10921 gctgatacgc gctgtaccgg ggtcgataac gtatttaata cccggtacgg tcagcgaggt
    10981 ttccgcgacg ttggtcgcca gcacaatgcg ccgtccactg tgcgactgga agacgcggtt
    11041 ctgttcgctg ttcgaaagcc gcgcataaag cggcaagatt tccgtatggc gtaagttcag
    11101 cttgttcagc gcatcggcgg tatcgcgaat ttctcgctcg ccgctcataa aaatcagaat
    11161 gtcgccaggg ctttcctggc tcagttcgtc tacggcatca aaaatcgcct gcaactggtc
    11221 gcgctcggtg tcatcagctt cttcaacaat cgggcgataa cgcacctcca ccggataggt
    11281 acgaccggag acttcgataa tcggcgcatt attaaagtgg cgcgaaaagc gttccgggtc
    11341 gatagtcgcg gaagtgataa tgatttttag gtcaggacgc cgcggcagca actctttcaa
    11401 atagccgagc agaaaatcga tattcaggct gcgttcgtgc gcttcgtcaa taatgatagt
    11461 gtcgtactgc atcagcaggc ggtcttgctg gatctccgcc agcaggatac cgtcggtcat
    11521 cagcttgacc atcgtgttat cacttacgtg atcgctgaaa cgcactttgt aaccgatgca
    11581 accgcccggc tccgttttca gctcttccgc aatacggttc gccaccgttc gtgccgccag
    11641 gcgacgcggt tgggtatgac cgatcagccc tttaataccg cgccccagct ccatacagat
    11701 tttcggtagc tgagtcgttt taccggaacc ggtttccccg gcgacgatca ccacctggtg
    11761 atcacgaatc gcttcgagaa tgtcctgctt tttctgacta accggcaaat tgtcaggata
    11821 agtaatttcc ggacgtgccg cttcacgcag caggactttc cctgccgcct ggtcaatctc
    11881 tttcgccatc tcctggaaaa tggcctgttg tgcatcagga tttttaacct tcttcacgcc
    11941 gtgcagacgg cgggaaaaac gcagtctgtc acgcagcatc agcgaatcca gccgctgctg
    12001 caaggccgta aaggtcaatt tttgttgttc tgtcataacg ttagtgggca gtaggctgcc
    12061 tgattaattt tcttttaaat gatagatata gagtaccaca tcgcggcttt ctatgcgttg
    12121 ttcaataaat tcgaacatag gcttcgattt attgcgctat ctctgtggca ggattgtgaa
    12181 taaagtgtca acaagcaacg gggcatcgcc cattcaaaca tctataagga aacaccatga
    12241 gcaaggtatt agttcttaaa tccagcatcc tggcagggta ctctcagtct aatcagttgt
    12301 ccgattattt tgttgaacaa tggcgcgaaa agcactccgc tgatgaaatc accgtgcgtg
    12361 acctggctgc aaatccgatt ccggtactgg atggcgaact ggttggtgca ctgcgtccga
    12421 gcgatgcgcc gctgactccg cgtcagcagg aagctctggc gctttccgat gagctgattg
    12481 ccgagctgaa atcccacgac gttatcgtta ttgcggcacc gatgtataac ttcaacatct
    12541 cgactcagtt gaaaaactat tttgacctgg ttgcacgtgc aggcgttact ttccgctata
    12601 ccgagaacgg tccggaaggt ctggtaacgg gtaaaaaagc catcgtgatt accagccgcg
    12661 gtgggatcca caaagatggc ccaacggatc tggtaacgcc gtatctgtcc acattcctgg
    12721 gctttatcgg cattaccgat gtgaaatttg tcttcgccga agggatcgcg tacggcccgg
    12781 aaatggcagc gaaagcacag tctgacgcga aagcagccat cgacagtatt gttgctgcat
    12841 aaccggacac tattttgatg tggactgtag atattcagtc cacatctcaa tccgcttacc
    12901 tgttttccca taatttcagc atcgctttgt gctcttcctt aagcacaatc cgcgagcgtc
    12961 tggctcgaat ataactaatc gcttcatcaa cggttttaca atgtccgtaa cataacagcc
    13021 atgccgccac caccagcgca ctgcgcgata atcccaacgc gcaatggacc agaacgccgc
    13081 cttgctcttc gcgtaatgtt tccaacatcg ccacggcctg tcggagctcc ccctcttccg
    13141 gaaccaccag atccagcatc ggtacacaaa aatagagttg atcttttgtg gctcgtccgc
    13201 gagggaattc aaaggtgacg tccagaaccg cattctgtgc cggaatatgt cgtggaaacg
    13261 cccctaaata aacaccagca gtaattttgc tcaccggctc caggcgaaga caaaaccaac
    13321 gcatagacag ccacatcccg atacgccagg gcaatgtcag ccagtaaacg gcgggcggga
    13381 gtttcccctg actatctttc cctgttgtta tcgcgccaag cccaccgtac ccacgaccaa
    13441 tgatgaatag cgataatact ggccaacata accagactga ccaccataac tgaagcatta
    13501 tcattagctc catcaacaca atgcacgagc acgcgcctac gacatatggc agtgctattt
    13561 tgattcgacg ttgatcaggt ttctgataat tccaacgacg gtcgacgggc accatccagt
    13621 caattaacat acctactgcc agccctgtga tgacatcaat aaaatgatgc tgccaggtcg
    13681 tcagcgtcga aatggcgatg agtaaaaacc atccgccgca gactttacgc cacctcacag
    13741 ccagatgctg acgaaagtga cgccaaagta gccagcagag aataatatgc agcgaaggag
    13801 actggttata aggcagatca aacagttcaa gttgcgaaaa tagccatcct gtcaccccac
    13861 tcacttcagg acggataaaa ctaaacttca gcggatagag aaaaaaaccg cagcaggcca
    13921 ttaccgttgc cagaataagc cggtgaacca gtcggcgctg ttcgaatgtc gagctacaaa
    13981 tgaacagcga aaatccatat ataagatcca gactccagta aggaacaata gtccagggaa
    14041 gaaaagggat cgccgtttcc caaccgaata cctgactggg gatatcatgg ttgttaagat
    14101 cctgagtcgc ggtgaactga ttaagaaatc cataggtgaa gaagaaaaac ggggccagca
    14161 acaataacca gccagctcct tgtagcaata cgttccggcg ttcagttatc acgacgcacc
    14221 gccatcgaaa ccgtaaaaat gccccactca tcaatccgtt gtgtgcattt atcaaatccg
    14281 gcatcatgca cgagcgaatc catctctcct tgagaacgca cgcgcattac ccacggttta
    14341 ccatctttat gactggttaa caccccggca atcagctcca gttgtgggtg ccacggctgc
    14401 ccggtgtaga tgagaatgcc acccggttcg atggcattgg caagacctgc gagggagttt
    14461 tttacctgct cattttcggg aaaaagctca tacaggccag agacaatcgc cagcgtaggc
    14521 cgcggagtta acgcgctgag ttcctccggg ttaaacgcat cgccctgttc aaaacgcacc
    14581 cgcccagaca ttccccgttg agcaatcatc tcttgcccct gtgcaacatt taactcgctg
    14641 taatcacgta acaaaatatc gcttacggca ggctcgtttg ccagcgcatc cagtacatag
    14701 cgcccatgcc ctgcggcaat gtcaaccacg cggacggcta aacctttggc gtggagatcg
    14761 gcaacggctt gtttaatcag tatttgtaaa tgggttttgc gctggcgaat accgcgccag
    14821 ccaacactgt tcaggtagat tttgtcgatt aagcgcccga atgcgttact accttgcggt
    14881 tgattttgat agacataatc cagcgaactg cctgaatcaa agccggtgct cattccgaga
    14941 tgcaggcccg cagagtgcgt cccgaacaat ttcatcgctt tacgcataaa gcgatacgcc
    15001 aaatcaaccg gcgataatgg cacgggtcca cctgaaagga gccgccagcg atccgctgat
    15061 ggtccagtgc ggtcttcatg ctgataatca aatttttgtg acttgttagc atataaacga
    15121 ctaataaagc tttgcatttt ttcaaatgcc tgcgccctgt tctcttcacc caacgtgtcg
    15181 tgataaaagc ctggcagcag atgcagctct ttcagagggc tacgtaatct ctgataaaaa
    15241 tcaatctgcg gttgacgatg caccacatag tcatcgcctg atatcagaag ttgcgtgggg
    15301 agcgtaatcg ccgccgcatc gctaacaata cgttcagacg ttttataaag atcgagcaag
    15361 atattaacgg caatcgcccg tgtgatcagc ggatcattat tgaaactcgc cacccgttgc
    15421 cgatcgtggg tcaaatagcg tcctttcaca taggaattaa taaaaaacag accacgcaga
    15481 cgatgccata acgccagcgc aggacgtgcc agcggcacat acaatttaac cttaaaggcc
    15541 ggagaagcca gcaccagccc gcgaatagca ggcgcataat catgaaccca tgtggcaacc
    15601 agcactgcgc cgacgctttg cgcgatcaca accacctctt ccagtccaac ctggctgtcg
    15661 ctggcagcaa aacggacaaa ttcatcgaca tcctgcactg aacgcgcaag agatgggcta
    15721 taaccacgcg gccctgacgt ttttccatgc cctcgggcat cccaggcata aaaagcagta
    15781 tctggcattg tcagttcatc aacgatatgt tgtagacgac cagaatgttc atggccacga
    15841 tgaaataaga cgatgacctt tttcgcaccc ggctgtaaag tgggccagtg ccgataaaac
    15901 aacgctgtat tatcactggt ggtaaaaaaa tgttccccag ggatgcgtga attttccatt
    15961 ttctctattt tccttcagta acagcagtag cgaataaaat aaaaaaatac cggagcggtg
    16021 aaaattaatg agtcaatcct gtcaaggagt ccgccatgtc ctggtaatag ttttccacta
    16081 tctttaacac caatatctcg tttgatggct gacatcacta catcgccgca aaaaccacta
    16141 ataccaatta acaaacccgc taataatgcc tgtaatgtat ttagcggtgt cagcaacggt
    16201 ccaataatta gtgacgcaat catggtggtg attacgcccc ccaccagacc ttccagcgtt
    16261 tttcccgggc tgactttggg gaccactttt cttctgccgc aggattttcc ccataaatac
    16321 tgtgcaatat cgtttgactc ggttaatgcc aaaagaaata acaccagtaa cgcctcgccc
    16381 tggatattta tggttggcaa cattaataac caggcggcat gactcaaggc gaaaacggtc
    16441 attatccagc cccaaaaaat ggcgctcact gtatgcagaa aaccggaggg gtcacccaca
    16501 aaaacttgcc aggtggctaa tatcagaaac ccagccaaag gtataaataa cagaaacagc
    16561 tcaaagcaat tatgaccgat aagcaaatag ttaagaggaa taccccaata taaccaacgc
    16621 ggaaaatgta cggatataag cgtacaatat tctttcaatg ccagaaaact tatcagcgca
    16681 aaaaacgtca acgtcatcca gcgtggacct gaaatcacca gtgaaaaaca aatgacgatg
    16741 ccccaccagg tacgaatacg taatgtaact tcatcccctt ttctctccgg taaccgccat
    16801 acccgaaaac ggtttatcag cgttgctaaa attaacaacg cgaaaagtgt tgccagagat
    16861 ttttccatca ttatctttca gcactcatca ggagcacact ccgacaacga ttaatcgcag
    16921 tccagataag cagaattgaa gcaatgcccc ataaaagatt attccattgc atccactgtg
    16981 gataaatggc aacggctagc ccccacagac caaatattaa cgcgcgatcg cttttgccaa
    17041 atggaccggc aaaactgcga ataccgttaa tcgtctgcgc gagtaaacca caaaactcag
    17101 tcaatatggt gcaaaataac atgagtatta cgagtgatgg gttactttcc ggtaaaaata
    17161 aaaacggtaa atagagcgca atatcggaaa taacatcgcc agtttcattc aaaatctccc
    17221 ccagacgtgt ttgctgattg cactcacgcg ccaacatgcc atccagcgca ttgagcgcca
    17281 tacggataaa aagcacgata ggcaatagca aaaagaggat gggttgtgcc accaacatca
    17341 acagcaatcc ggtaagaaga gaaagcgcca gtgcagcaag agtgatgtga ttcgctgtaa
    17401 cgtggtgctt ataaagccaa aacatcgtcg gccttaacag cgactgaaag agcggtttta
    17461 tctggtagag cgtcattatc aatccttgat aattcggttt gcgctatggt gcatcaattc
    17521 ccctgatgga gatatcgcaa cacgccgctt cattaaaaat tcagaatata tcaaggtatt
    17581 ggggactcac tgtcaggaat gattatcccc gattaatcaa agggttaaaa aatattacgc
    17641 tgttattcaa tacaactcat caagttttct catcgcttgt tcccgtattg cgcgcgtctt
    17701 accgttaagc gccagctggc ggactaaatc cagttcaggt ttaacaagct ctaacgccag
    17761 caaaggatca cgtttcagcc tcgcctttaa tacatcaact ggaaaacggg gattattcat
    17821 cgccacaatc caccactcgg gatcaatttc tgccgccagt gccgcagacg gtgtatggcg
    17881 attgttaagt gcaccgaact tgaaaaatgt aagattgctt ttcgccagcg aactccacca
    17941 tatacgatcc ggttgttttg ccagtacatc cagttgtgct aacgcatcgg ggtctagtgc
    18001 ataataaaca cgtaacgctt cgttaacctg cgcacgagag ctgttttcct gcctcagaaa
    18061 aaacttcgcc caaatatcat tgcgtggcat attttgctgt aattccttga ggacaacagc
    18121 gggtaaatta tcccaactaa ctaatgcact ctctaaaaag tcccagcctt ccgaacgtat
    18181 cagagaggcg gcatttaata gcatctggtc atcaacttca ccgtagctga taagctccga
    18241 caaaatcata tcagcgctgg tttcatatgc tgcagaatct gctttcggat tattttttcg
    18301 atgcgataaa gcgcgatgcc aaattttttg tttcatcgcc gtactcagat actgattttt
    18361 cgccagatta ctccacccct caggatcgtt gaaacgtgtc aataaccgtt gtaaagcagc
    18421 gtcagagtga attacctgca tatcccgaca gcaaaagtag gcaggggatt ttttctccat
    18481 ccttttaaca aaattaaact gtaagttatc tggcaacgct aaaaataacg cacctattag
    18541 atcatcgtca ttctcgaatt tttggtataa atatactgct attttgtcac tctcttgtgg
    18601 cgtcatccgc aacaattgac catggtgttt catctctgcc agctttgacg ctaagcttgt
    18661 gacaacatcg tttgatgaat cgttcgccaa ctgcattgcc tgattgtagg tgagttgtcc
    18721 tccagcaccg acctgacgaa tagaggaatc atcactgcgg atatagccat caataatgga
    18781 ttcgggcaat aaccacgcat ctttataaag ctcctgaatg atcatatccc aatctctttt
    18841 cgccagagtc atgacgatat ccagagggag attttcacgt agcgcaagat tcaacggacc
    18901 gacaccatca ggtagatgac tcattcgcgt cattatttcg acagagagcg gttcacggtc
    18961 gagcaacccc agaacaacag gctggtaacc caattgctga tcggtcaact ccagaatctc
    19021 attgtcaggc atatatctcg ccatactttc aatcgtttgt ccatcattgc tattaataag
    19081 ttgtttgcgt aggttagctg aaattccttt aagccttggg agagttcgca ttatggcaag
    19141 atcaaatgtc gcaatatctc gtccttcaaa tgcagcaacg ttgccttcat ccagcatttg
    19201 caattcctgc actaactcag gagaaggctt agggcgaaac agcgcttctt ttttcatcag
    19261 attacagaca ttccctgcca tgcgaatatt gcttcgctta aaaatttctt tcagagcatc
    19321 ttcatcattt attagatccc aataatatgc atcaggattt attatcatca gcgctttttt
    19381 gacattttca gtgtcatttt tgtcactcgc acggaccatg aattcactat ttgtcgaaga
    19441 cgcaacaaca ggtgcaatta tgtcattgat aaatatccca cgcgcattaa tactcccctt
    19501 aatcgtagac ggattatcgt aatatgagtc gataaatacc agtccacttg catttatcga
    19561 accggtaatt aacagtggtg aatccgtaac tatattcgtt gccgtcacgt taccgagaat
    19621 aacccatgga ttagaaagag agaaagtgga aatattacct ttgactgtca aattgccaag
    19681 aacaatcaat ttttgattac tctctatatt accgtctacc actaaatcgc cacgatgcac
    19741 tttccagtcc gatgcagata aaccgaaggg gacaagattc acgctactgt tgatagcttg
    19801 ttcaacttgt tgtttatctt cagcggtagc cgcagaaaaa aatggttcaa tatcaactgc
    19861 atttgcaaca catcgaaggt ccgcctgtac tggaagactc agcataaaca ggggaagtaa
    19921 acctatccag ctgcaaatcc tgggcttaaa catatgcact ccatgccatt aaaaaagaaa
    19981 caaaagggaa atgcatcttt cccttttgta tattcgttat tctcgcgaaa taccatccaa
    20041 cgtagacaac acttcctcag aaagatgcaa tttttctgcg gccatattct cccgtaaatg
    20101 cgcaacagaa gatgttccag gaatcaacaa aatattcggt gaacgttgta acagccacgc
    20161 cagcgctacc tgcattggtg ttgcacccag gctcgcagca acatcggaaa gcgttgaaga
    20221 ttgcagcggc gtaaagcccc cgagcggaaa gaacggcacg taggcaatgc cgtcacgagc
    20281 caaagcatca atcattgcgt catcagcacg atgagcaatg ttgtattcgt tctgcacaca
    20341 gacgatttcg gtaatcttac gcgcctctgc aacctgcgtc ggtgtgacgt tgctcaggcc
    20401 aatatgtttt accaggcctt gttcttgcat ctctgccagc acggtcaggc tggcttcaat
    20461 cgatccttcc gctgggccat gaccatcccc catcataacg cgcaggttaa ccacatccag
    20521 tacgtccagc ccgagattac gtagattatc gtgcaccgct ttttgcaact ctgccggaga
    20581 aaatgcgggc aaccaggagg cgtcctctcc acgccgcgcc ccaattttag taacaatggt
    20641 caggtcgtca gagtaaggat aaagcgcttc gcggataatc tgattggtga cgtgcggacc
    20701 ataaaagtcg ctggtatcaa tgtgattgac gcccaatgcc agcgcctcac gcagcacggt
    20761 tatagcgacg tggcgatctc ttggggggcc aaaaacccca ggacctgcca gttgcatcgc
    20821 gccataacca agacggttaa cggattttgt accgagagta aatgtattgc tgctcatcgc
    20881 accctgccct gtaataaaac gaattcagaa aaatcagtat agaaacgaaa agagttaaat
    20941 aatgcgaagg cgtaaacaag attactggat gagttgctct attgtcctgg aagacaccaa
    21001 aacaaaacgc gtcaagcgcc gcatccggca ataaaaaacc gcaacctgta tcagcgttgc
    21061 ggtttaggta tcacatgcta aaaattagaa cgtccagcat caggacgtta ctgtttcggt
    21121 cgcagattct catcaaatac caggcgctgc ctgccaggtt caacttcccg caatggctcg
    21181 acttgatgta acgtctgctt acagcgtgtc accagcacct ggtactcatg cgtaccctgc
    21241 tttttccatg ccaactcctg ctcactgagt tcacgaatcg ctttcgccgg gctgccgaca
    21301 atcaggtaat tagctggcat ttctgctttg gctttcacaa atgcggatgc gccaacaatg
    21361 ctgttctcgc caatcaccgc accgtctatc actaccgcgt tcattcccac taatgcattg
    21421 cggcggataa tgcagccgtg aaggatagcg ctatgaccaa tatgtccatc ttcttccacg
    21481 acagtatcct gctcgggaaa accgtgcata acgcaattat cctgaatgtt cgcgctatct
    21541 ttcaccacga tacgaccaaa atcgccacgc aggctggcat ttggcccaac gtaaacgccc
    21601 ttgccgagaa taacatcgcc gatcaatacc gctgtcggat ggacaaaact ctcttctggc
    21661 acaaccggag tcagaccgtc tatctgataa attggcataa cgcctcctgt tcaatattca
    21721 agccgccaaa acgttgaaaa tacaggcttc ccggcgcagg caattcaccg accgaggttt
    21781 cacctttttc actaacgaac gctaaagcag caggcgctac gcgctgataa agtttgccga
    21841 taaaggtttg gtagtcgcgc aatatatccg taaccgtcgt ctcgattttt gtgcagatgc
    21901 gattcgccat gccgcagatg atgaaaaact ggcaggcatt ggctttcatt ggggattttc
    21961 cgaccagagt catttttcaa cggtatttaa gcaacgcttt gggatgacgc caggcgagta
    22021 tcgacgtaaa ttccgctaac taattagcgt tgcatgtaca gcaacgctaa ttagttaaaa
    22081 cagatatttg actattcatt ttcagggcga aaggcaattt gacaggagtt tttgaataat
    22141 catcttgttt ccggaaaata gattaatcgc cttctcctgt agcgttatcc cgatagtgcg
    22201 gttttgctat taaaattttc gcacccattt accgtttatc ccttgtacat attcccccgg
    22261 tttggcccga gctacgagct tttgcccggc gagtttcgcg atatcatcta ccgacacatt
    22321 attttgcttt gccagttgtt ggtaactcgc tttacgttcg gcattaatgt cgtttactaa
    22381 tttctctgtt tcagcatctg ttttcagcgc aaccagataa ccataaaatg tttcacctac
    22441 ccgcccctga gttctggctt catccagagt caatgccatt acattgctgc ttaccagccc
    22501 aacaagaaac gcacaaagaa gtaatgtttt cttcatcatc gcctcagaaa agatcgctac
    22561 gagtttcaag cagctcttcg acatctttgt ctgccttgat gatgatctca tgctcaattt
    22621 taacgttcat attgatagtg atcggttcct taggggcagc gacttcaatg cgaggcgtac
    22681 agccaaccag cataaaagat gacgtcaacg cagccagtaa aattttcatt gtttttcctc
    22741 acactctttt ccttgcggac agtcatttcc cggcagacgt gcgttctgct ccaaccatgc
    22801 ctggagatta tcgccaaagc gtaaactgcg ccacagcgta aaaatattct cttcatgatg
    22861 gtaattaaga tttaccgtac cgcttttacc atcaacgcga ctggtacctg taatgttggc
    22921 ctgcatggtt aataaaccga gattatctaa attaattttt gtcgatgaac ggctaatttc
    22981 catatagcgc aaccagttaa ttgctgaacc cgcagtcata ttgtctttca ccaccgcatc
    23041 tgcggtgtct ttatccagcc gcaaggtcat tggcccgcta tttgccagcc aaccatcttt
    23101 cactatccat ttttcgttgt ttagccataa cggcaatgca ccactaaatg ccccggacat
    23161 ggcgaattgt ttcggattga cggcgctaac cagttcgctg gaggaaagat tattcagccg
    23221 caacagcgcc gggtcatgtt gcggcatacg taattgtttc atcagtacgt taccgcctaa
    23281 cacatcaacg ctaacatcag tcaacagcaa tggttcttct tcagtccacg gataacgacc
    23341 ttgcaaatca gccgtaatat ttttcgctgt caccagatta atcacttcgg caattcgcaa
    23401 cgtaacgggg ccgcgagtcc ccagatgcca ggctccatcg gcaaaacgga aaggcaggac
    23461 aaaatcgaca ccgttaacct gattatctgg catccaggca ctaccgcctt tcaacacacc
    23521 gtgccctccc gcgcggaatc cttgttcagg cgcagcagaa aatgcgacct gggcatatag
    23581 ttcgccatcg cgtaagttca tcttccagtc gggtggcacc agcggctgga atacggtcag
    23641 tgattgttta ggccaccagg cgttaccgcg cagacgaata ccgtcccagc gaccatttac
    23701 ccgaaccggg ccaatctcac cagcatgtaa atcgccttta aagaggaaat acgtcggatc
    23761 gcgtccatcg acgctaaatt ttaaggttga tggcggtaac acactgccgc cagtgaacag
    23821 cgtttgcccg gcgtccagtg acagcgcgcc gctaaaggag ggatgctgtg cgtcacgtac
    23881 ccagacgacg ggcttgtcga gaattagtcg cggcttttca accgtcatcg taccgtattg
    23941 taactggtcg aaaccggtgg agagatcggt cagcgtaatc gtgctgtcat gccactcacc
    24001 ctttcctgcg acatcccagg tggcattcat cggtgtaaaa ctgccttttc cccagtagcg
    24061 ccactgccag cggccagcgt cagggagaaa atcattcgcc agtccatcca tatgcagcac
    24121 gaaatcgccc agttcatttt catgcgcctg caaaatggcc tgcaaacgtc cgtcaacacc
    24181 acgttgggtg acttttacac ccgctaaagg ccagcggatt tcatcgatgt ccagcgaatc
    24241 gatgactctt cccttcgaac gtaataacgc gcctggctca aaggccagcg ttgggtcagt
    24301 cagacttccg cttagctgcg caggtaagcg ggcgtataaa atgagatccg cctgtttcgc
    24361 ttcaccggtc agctgcatag gcagctggct gttatccatg cttaattttc cagggccaaa
    24421 attaagcacc gcgttgccct tacccgcttg cccctgggtc agcacactca gtcgtccgct
    24481 gaccagagcg ttctcgagcc ctgcctgcca gttgtcgact ttgacaccca gtcggccact
    24541 caaaggaaaa cctgcatacg gccagctcca gcgaccatcg cttacggtca attgttgacg
    24601 agtaatttgc cacggcaaat cgagcaacgg atcgccgtta tcccgtgcca gcacgatcaa
    24661 ttgcccgcta ttttcctgcc agtccagctc tgcatccacc agtgacggtt cctgcggcaa
    24721 gtttaacgtc gcagtagcat gcccacttac cggaagtcca ttcggcacga gcggcatagt
    24781 aaattccccc accagtttaa ccggcggctg attttcaaac gcgacgacat ccagttcgct
    24841 gactgtaagt tgttgccctt tcagctggcc ttgaaattta actttttcgc cctgataacg
    24901 cagttgctgg atatcggagg ttaatgcgag agagagtttt ccctgccatt cctgccaggg
    24961 agaaaaaatc agtttatcga tattgatcca ggtgttaggc aacatggcct gccactgcgc
    25021 gagggttttt ggagcggctg gcgattgctc cgtctgcggc aatttcgcca gacaagcaga
    25081 atcaagttct accgtgccga cgttcaataa ccagcggctg ggatgtgaaa ggctggcgtt
    25141 ggtgatatgc gcaagctgac aatctcccac cagataacgg agatcgggaa tgattaaacc
    25201 tttacgcgta atgcgtgggc tttcatctaa tgcaatacgt gtcccgagcg gtagccagat
    25261 gcccgccagc gtaggaaccc acagcccgag cgtcatcagc agcgtcaacg gcacaagaat
    25321 aatcagtaat aacagcgcga gaacggcttt atatttaccc agcatgggta gttaatatcc
    25381 tgatttagcg aaaaattaag cattcaatac gggtattgtg gcatgtttaa ccgttcagtt
    25441 gaaggttgcg cctacactaa gcatagttgt tgatgaattt ttcaatatcg ccatagcttt
    25501 caattatatt tgaaattttg taaaatattt ttagtagctt aaatgtgatt caacatcact
    25561 ggagaaagtc ttatgaaact cgccgtttat agcacaaaac agtacgacaa gaagtacctg
    25621 caacaggtga acgagtcctt tggctttgag ctggaatttt ttgactttct gctgacggaa
    25681 aaaaccgcta aaactgccaa tggctgcgaa gcggtatgta ttttcgtaaa cgatgacggc
    25741 agccgcccgg tgctggaaga gctgaaaaag cacggcgtta aatatatcgc cctgcgctgt
    25801 gccggtttca ataacgtcga ccttgacgcg gcaaaagaac tggggctgaa agtagtccgt
    25861 gttccagcct atgatccaga agccgttgct gaacatgcca tcggtatgat gatgacgctg
    25921 aaccgccgta ttcaccgcgc gtatcagcgt acccgtgacg ccaacttctc tctggaaggt
    25981 ctgaccggct ttactatgta tggcaaaacg gcaggcgtta tcggtaccgg caaaatcggt
    26041 gtggcgatgc tgcgcattct gaaaggtttt ggtatgcgtc tgctggcgtt cgatccgtat
    26101 ccaagtgcgg cggcactgga actcggtgtg gagtatgtcg atctgccaac cctgttctct
    26161 gaatcagacg ttatctctct gcactgcccg ctgacaccgg aaaactatca tctgttgaac
    26221 gaagctgcct tcgaacagat gaaaaatggc gtgatgatcg tcaataccag tcgcggtgca
    26281 ttgattgatt ctcaggcagc aattgaagcg ctgaaaaatc agaaaattgg ttcgttgggt
    26341 atggacgtgt atgagaacga acgcgatctt ttctttgaag ataaatccaa cgacgtaatt
    26401 caggatgacg tattccgtcg cctgtctgcc tgccacaacg tgctgtttac cgggcatcag
    26461 gcattcctga cagcagaagc tctgaccagt atttctcaga ctacgctgca aaacttaagc
    26521 aatctggaaa aaggcgaaac ctgcccgaac gaactggttt aatcttgccg ctcccctgca
    26581 ttccagggga gcttattcag ataatcccca aagacctttc atcctctatt cttaaaatag
    26641 ccctgagtca gaaactgtaa ttgagaacca caatgaagaa agtagccgcg tttgttgcgc
    26701 taagcctgct gatggcggga tgtgtaagta atgacaaaat tgctgtaacc ccagaacagc
    26761 tacagcatca tcgctttgtg ctggaaagcg taaacggtaa gcccgtgacc agcgataaaa
    26821 atccgccaga aatcagcttt ggtgaaaaaa tgatgatttc cggcagcatg tgtaaccgct
    26881 ttagcggtga aggcaaactg tctaatggtg aactgacagc caaaggactg gcaatgaccc
    26941 gtatgatgtg cgccaaccca cagcttaatg aactcgataa caccattagc gaaatgctga
    27001 aagaaggtgc acaagtggat ctgaccgcga accagttaac gctggcgacc gcgaaacaga
    27061 cattaactta taagctggcg gatttaatga attaatagct gccacagctc ccggcggcaa
    27121 gtgactgttc gctacagcgt ttgccgttgg gtaatgcaca catcccaatc gccgtaccat
    27181 ccagttgacg ggcaacagaa agcgaaccgc cgatcattgc acaatttgct tctccactac
    27241 tggacatcga cgcttttaaa cctggcgcta cgtgcgccgc agtcgcctgc tgaacaggtt
    27301 cactactaca cgccgacaat aataaagcgg cacaccctac ccaaaacgct gctcgcatct
    27361 tttcttcctc tgatcttcaa gccaaacgac accgccataa ataataggca gcacagaggg
    27421 cggcgtcgag agctgtcctg cgcgttgccc cgcattttta cttttttatg gctatttttt
    27481 tgccctctgt ttgatcaaaa cattcattac actgatatgg gggacacaaa agcgaaaatg
    27541 cagaagaaag ccatttgcta aaattgaaag ataactactg ggcgcgcagc aatttcgtgc
    27601 gcccctcatt tgcgcaatgt aagggtgtca tatgattact attgacggta atggcgcggt
    27661 tgcttcggtg gcgtttcgca ccagtgaagt tatcgccatc taccctatta cccccagttc
    27721 cacgatggca gaacaggctg atgcctgggc cggaaacggc ttgaagaacg tttggggaga
    27781 cacaccacgc gtggttgaaa tgcagtcgga agcgggtgct atcgctaccg tgcatggcgc
    27841 tttgcagacg ggtgcccttt caacatcgtt tacgtcatcg cagggtttgc tgctgatgat
    27901 cccgacgctg tacaaactgg caggcgaact gacgccattt gtcctgcatg tagcggcacg
    27961 taccgttgcc acacatgcac tctctatttt tggcgatcat tccgacgtta tggcggtgcg
    28021 ccagacgggt tgcgcgatgt tgtgtgcggc taacgtccag gaagcgcaag actttgctct
    28081 catttcgcac atcgcaacgc tgaagagccg cgtgccattt attcatttct ttgatggttt
    28141 ccgcacgtcc cacgaaatca ataaaattgt cccgctggcc gatgacacta ttcttgatct
    28201 catgccgcag gccgaaattg atgctcatcg cgcccgggcg ctcaacccgg aacatccggt
    28261 gatccgcggt acgtccgcca atcctgacac ttatttccag tctcgcgaag ccaccaaccc
    28321 ctggtacaac gcggtctatg accatgttga acaggcgatg aatgatttcg ctgccgcgac
    28381 aggtcgtcag tatcagccgt ttgagtatta cgggcatccg caagcggaac gggtgattat
    28441 cctgatgggc tctgccattg gcacctgtga agaagtggtt gatgaactgc taacccgtgg
    28501 cgaaaaagtc ggcgtgctga aagttcgcct gtaccgtccc ttctccgcca aacacttgct
    28561 acaagctctg ccgggatccg tacgcagcgt ggcggtactg gacagaacca aagaacccgg
    28621 tgcccaggca gaaccgctct atctggatgt gatgaccgca ctggcagaag cctttaataa
    28681 tggtgagcgc gaaaccctgc cccgtgtcat tggtgggcgc tatggtcttt catccaaaga
    28741 atttggcccg gactgtgtac tggcggtatt tgccgagctc aacgcggcta aaccgaaagc
    28801 gcgctttacg gttggtattt acgatgatgt gaccaatctg tcactgccgt tgccggataa
    28861 caccctgcca aactcggcga aacttgaagc cttgttttat ggccttggta gtgatggcag
    28921 cgtttccgcg accaaaaaca atatcaagat tatcggtaat tccacgccgt ggtacgcaca
    28981 gggctatttt gtttacgact ccaaaaaggc gggcggcctg acggtttctc accttcgcgt
    29041 gagcgagcag ccgattcgtt ccgcttatct gattccccag gctgattttg ttggctgcca
    29101 ccagttgcag tttatcgata aatatcagat ggctgaacgt ttaaaacctg gcggcatttt
    29161 cctgctcaac acgccgtaca gcgcagatga agtatggtcg cgcttgccgc aggaagttca
    29221 ggccgtgtta aaccagaaaa aagcgcgctt ctatgtgatt aacgcggcga aaatcgcccg
    29281 cgaatgtggc ctggcggccc gtattaatac cgtcatgcag atggcttttt tccatcttac
    29341 gcaaattctg cctggcgata gcgccctcgc agaattgcag ggtgcgattg ccaaaagtta
    29401 cagtagcaaa ggtcaggatc tggtggaacg caactggcag gctctggcgc tggcacgtga
    29461 atccgtagaa gaagttccgc tgcaaccagt aaatccgcac agcgccaatc gaccgccagt
    29521 ggtttccgat gccgcccctg atttcgtgaa aaccgtaacc gcggcgatgc tcgccgggct
    29581 tggtgatgcc ctccccgttt cggcgctgcc gccagacggc acctggccga tgggcaccac
    29641 gcgctgggaa aaacgcaata tcgccgaaga gatccccatc tggaaagagg aactctgtac
    29701 ccaatgtaac cactgcgtcg ctgcttgccc acactcagct attcgcgcaa aagtggtacc
    29761 gcctgaagcg atggaaaacg cccctgccag cctgcattcg ctggatgtga aatcgcgtga
    29821 tatgcgcggg cagaaatatg tcttgcaggt ggctccggaa gattgcaccg gttgtaacct
    29881 gtgcgtcgaa gtttgcccgg cgaaagaccg tcagaatcca gagattaaag ccatcaatat
    29941 gatgtcgcgg ctggaacatg tcgaagaaga gaaaatcaat tacgatttct tcctcaacct
    30001 gccagaaatc gaccgtagca aactggaacg tattgatatt cgtacatcac agctgattac
    30061 accgctgttt gaatattccg gtgcttgctc cggttgtggc gagacgccgt atattaaatt
    30121 gctgactcag ctgtatggcg accggatgtt gatcgctaac gctacgggat gttcttcaat
    30181 ttatggcggt aacctgccct ctacaccgta tactaccgat gccaacggtc gcgggccggc
    30241 atgggcgaac tcgctgtttg aagataacgc cgaatttggc ctgggtttcc gcctgacggt
    30301 cgatcaacac cgtgtccgcg tgctgcgtct gctggatcaa tttgccgata aaatcccggc
    30361 ggaattactg actgcgttga aatcagacgc tacgccagag attcgtcgtg aacaggttgc
    30421 agctttacgc cagcaactca acgatgttgc cgaagcacat gaactgctac gtgacgcaga
    30481 tgctctggtg gaaaaatcaa tctggctgat tggtggtgac ggctgggctt acgatatcgg
    30541 ctttggtggt ctggatcatg tattgagttt gacggaaaac gtcaatattc tggtgctgga
    30601 tacgcaatgc tattccaaca ctggtggtca ggcgtcgaaa gcgacaccgc tgggtgcagt
    30661 aactaagttc ggcgagcacg gcaaacgtaa agcgcgtaaa gatcttggcg tcagtatgat
    30721 gatgtacggt catgtttatg tggcgcagat ttctctcggc gcgcagctga accagacggt
    30781 gaaagcgatt caggaagcgg aagcgtatcc gggaccatcg ctgatcattg cttatagccc
    30841 gtgtgaagag catggttacg atctggctct cagccacgac cagatgcgcc aactcactgc
    30901 taccggcttc tggccgttat atcgctttga tcctcgtcgt gccgatgaag gcaaactacc
    30961 gctggcgctg gattcacgcc cgccgtcaga agcactggaa gaaacgttac ttcacgagca
    31021 gcgtttccgt cgtctgaatt cgcagcagcc agaagtggca gaacagttat ggaaagatgc
    31081 tgcagctgat ttgcaaaaac gctatgactt cctggcacaa atggccggaa aagctgaaaa
    31141 aagcaacacc gattaaatgc tctggataag gattatccaa ttctaaaaaa aagcccggac
    31201 gactgttcgg gcttgtctca ttatttgttg gataaacagt aacaagggtc caacagaaaa
    31261 taatctttgt gacaataaag gcatataacc cgcgaagaat aacgcatcac tatttaaatg
    31321 tataattttt attttgtata tgtcgccaac aatatattca ccaaacttat tatcatttcc
    31381 gtagaattat ttgattaagg ttttacttaa ggcgtaacaa atgatattta tcggctaact
    31441 gaacttctcc tttaggatgt tttcactccc cgaaatgggg ataaaaggca aataaaataa
    31501 ctaaaggatt tattcaatga aaagcaaagt actggcactt ttaattcctg ccctgctcgc
    31561 cgcaggtgct gcacatgcag ccgaagttta taataaagac ggcaacaaat tggatctgta
    31621 tggcaaagtt gatggcctgc attatttttc tgataattca gcgaaagatg gcgaccagag
    31681 ctatgcgcgt ctgggtttta aaggcgaaac ccaaattaac gatcaactca ctggctacgg
    31741 tcaatgggaa tacaatattc aggcaaacaa cactgaatct tcaacaaacc agtcatggac
    31801 ccgtctggca tttgccggac tgaaatttgc agattacggt tctttcgatt acggacgtaa
    31861 ttatggcgta atgtacgaca tcgaaggctg gaccgatatg ctgcctgaat ttggcggtga
    31921 ctcttatacc aatgcagaca actttatgac tggtcgtgcc aacggcgtcg cgacttatcg
    31981 taatactgat ttcttcggtc tggtaaatgg tctgaacttc gcggtgcagt atcaaggtaa
    32041 caacgaaggt gccagtaatg gtcaggaagg caccaacaac ggacgtgatg ttcgccatga
    32101 aaacggtgac ggctggggtc tttccacaac atatgattta ggcatgggct ttagcgctgg
    32161 tgcggcatac acctcatctg accgcaccaa tgaccaggtt aaccatactg cggcaggtgg
    32221 tgataaagca gacgcgtgga ctgctgggct aaaatacgat gctaacaata tttacctggc
    32281 aaccatgtat tcagaaacgc gtaacatgac cccgtttggc gacagcgatt atgcagttgc
    32341 gaacaaaacc cagaactttg aagttactgc acagtaccag tttgattttg gtctgcgtcc
    32401 ggcagtctct ttcctgatgt ctaaaggccg tgaccttcac gctgccggtg gtgcagacaa
    32461 cccggcaggt gttgatgata aagatctggt taaatacgcc gatgttggcg cgacttacta
    32521 tttcaacaaa aatatgtcca cctacgttga ctataaaatc aacctgttgg atgaagatga
    32581 cagcttctac gctgccaacg gcatctctac cgatgatatt gtcgctttag gtctggttta
    32641 tcagttctaa atcctcctgc ccgctgttat ggcgggcttt ttctgcttat tcttcctcct
    32701 ttgatctaaa ttaaaaatgt gaactccgtc attacacaaa aagtgtcatc tggcgttaca
    32761 ctttatgcgg atactaaaac aggaggtttt atgaacagaa cgattcttgt ccctatcgat
    32821 atttccgatt cagaattaac tcaacgcgtg attagccacg ttgaggcaga ggcaaagatt
    32881 gatgatgcag aggttcattt cctgacggta ataccttcac tgccctacta tgcctctctg
    32941 ggtttagcgt attccgcaga attaccggca atggatgacc tgaaagcgga agccaaatcg
    33001 caactggaag agatcattaa aaaatttaaa ctgccaaccg acagagtgca tgtccatgtt
    33061 gaggaaggct cgcccaaaga ccgcattctg gaattggcga agaagatccc cgctcatatg
    33121 atcatcattg cttcccatcg accggatatc accacttatc tgctcggttc taacgccgca
    33181 gctgtcgtgc gtcacgcaga gtgctccgtg ctggttgtgc gctgacacta acgcccgcac
    33241 attgctgcgg gctttttgat tcatttcgca aatgtgctga cattttcccc tctaatccgt
    33301 accatacacg ccacagtttt tatatcagat ttcttatgct gggcgttccg gcatgacgca
    33361 tactcttctg atgccatata acgaattgag tcgcttttaa atgtcgcaaa atcaagaaat
    33421 tagtaagaaa gaacaataca acctgaacaa attacaaaaa cgtctgcgtc gtaatgtggg
    33481 cgaagccatt gctgacttca atatgattga agaaggcgat cgcatcatgg tttgcctctc
    33541 agggggtaaa gacagctata ccatgctgga gattctgcgc aatttgcagc aaagcgcgcc
    33601 aatcaatttt tcgctggtgg ctgtcaacct cgatcaaaaa caaccgggct tcccggaaca
    33661 cgttctgccc gagtatcttg aaaaactggg cgttgagtac aagattgtgg aagagaacac
    33721 ttacggtatc gtgaaagaga agattccgga gggcaaaacc acttgctcac tgtgttctcg
    33781 tcttcgtcgc ggaattcttt accgtaccgc aacggaactg ggagcgacga agatcgcgct
    33841 gggtcaccat cgtgacgata tcctgcaaac gttgttctta aatatgttct acggcggcaa
    33901 gatgaaaggt atgcctccga aactgatgag cgatgatggc aaacatatcg ttattcgtcc
    33961 gctggcctac tgccgcgaga aagatattca gcgctttgcc gatgcaaaag cgttcccgat
    34021 tattccgtgc aacctgtgcg gttcacagcc taacctgcaa cgtcaggtga ttgctgacat
    34081 gttgcgtgac tgggataaac gttatccggg gcgtatcgag acgatgttca gcgcgatgca
    34141 gaatgtggtg ccgtcgcatc tgtgcgatac caacctgttc gatttcaaag gcattaccca
    34201 cggttctgaa gtggttaacg ggggtgatct ggcgtttgat cgcgaagaga tccctctaca
    34261 accggcgggt tggcagcctg aagaagatga aaatcagttg gatgagttac gactgaatgt
    34321 ggttgaagtg aaataacccg gatagcgccc gatgcgcaag cttatcgggc tactcttatg
    34381 gaggccggag aagacgcggc cagcgtcgca tccggcaatc ccgaataaga tgtttactct
    34441 tgcacccggc aattcaacat ttcattattt taataaccgc acccggcacg tttttccttt
    34501 aatcttcccg ccctgtaact gtttccatgc tttatgagca acagcctgac gcaccgcgac
    34561 atagacatgc gccggatgca cggcgatttt gccaatatct gcgccatcaa gcccgatgtc
    34621 tcctgtcagc gcacctaata catcacccgg gcgcattttg gcttttttcc cgccatcgat
    34681 acataacgtt gccatttctg cttccagcgg cacaatggaa ctattaactg gcggcgtttg
    34741 ccagttaagt tttatctgca acatgtcaga aatgatattg gcccgctgtg cttcttccgg
    34801 ggcacagaaa ctgatcgcca gaccgctatt tcctgcacgc gctgtacggc cgatgcgatg
    34861 tacatgaact tcagggtccc acgccagctc aaagttcacc accagctcaa gcgatttaat
    34921 atccagacca cgcgcagcaa catcagtcgc aaccagtaca cgggcgctac cgttagcaaa
    34981 acgtaccagg gtctgatcgc gatcacgttg ctccagatcg ccgtgtaacg acaatgcact
    35041 ttgctctact tcattcagcg cgtcgcagac agcctggcaa tcttttttgg tattgcaaaa
    35101 caccacgcaa gaggatggct gatgcaaact taataaccgt tgcaacaacg gaattttgcc
    35161 tttgctggat gtctcataaa attgttgttc aataggtggc agagcatctg ttgagtcaat
    35221 ttcaatcgct aaaggatcgc gctgcactct tccgctgatt gcggcgatgg cttccggcca
    35281 ggttgccgaa aacagaagcg tctgtcgaga tgcaggcgca aaacggatga catcatcaat
    35341 ggcatcgcta aatcccatat ccagcatgcg gtcggcctca tccatcacca aagtattcag
    35401 cgcatccagt gataccgtgc ctttttgcaa gtgatccagc aaacggcccg gcgttgccac
    35461 gataatatgc ggcgcatgtt gcaacgaatc acgctgcata ccgaacggtt gaccaccgca
    35521 caacgtcaaa attttggtat ttggcagaaa acgcgccagc cgacgcaatt cacctgccac
    35581 ctgatccgcc agttcacgcg taggacacag cactaaagcc tgggtttgaa atagcgacgc
    35641 atcaatttgc tgtaacaagc cgaggccaaa agccgccgtt ttgccgctgc cggttttcgc
    35701 ctgcacgcga acatcttttc cggcaaggat cgccggaagc gcggcagcct gcaccggcgt
    35761 catagttaaa taacccaact cattaaggtt cgtgagttgg gcgggaggca aaacattcag
    35821 ggtagaaaaa gcggtcacaa tctattctcg tggtcatcga cgcaaagtta gcaggcgcgt
    35881 atcctcgcag atctacgctc acgatgcgac aatttaatcg gttcttcatc gggtggtggg
    35941 tcaggcatgg gttgcgggcg agggatcgga tctggtactg gaacaggatc gccaggaatc
    36001 ggttcaggga caggaatttg caaataaata agtgtcgtca tatttccctc cggtcattgg
    36061 gtggactctt aaagggtaga cgctgataaa taacaggcaa aaaaaagccg actcatcaaa
    36121 gtcggcgtcg tacgaatcaa ttgtgctatg cagtaattca aaaaaggaag taagacaata
    36181 tggagcgcaa cgcccatcgc ttgacgttgc attcacctgc gagagagata ttgccctgaa
    36241 taggtaggga gtttattgac ttcgctcaaa ctttacggcg tttttgtata cagaatcccg
    36301 gagaaattgc ttttgttaca accatttact acgatgcaac cataaagcaa caccgccaat
    36361 aagaacaact aacagaatac aaaaaattga aaatccgaat tgccacccgc cgccagggat
    36421 cccaccaagg ttgacgccaa ataacccggt cagaaaggta ctgggtaaaa agaccattgc
    36481 catcaacgac attgtatagg tacgacgcgc taaattttcc tgcatcacct gagcgatttc
    36541 atccgccatc acgccagtcc gtgctataca ggcgtcgatt tcgtcaaggc cgcgcccaag
    36601 gcgatcggca atatcctgca tccgacggcg ttggtcatcg ctcatccacg gcaaacgttc
    36661 actggcaaga cgagcataaa catcacgttg cggtgccata tagcgacgca tcacaattaa
    36721 ttgtttgcgc agcagagcca ggaatccacg cggtggaatt tgctgatcaa ggagattatc
    36781 ttcaaggtcg ataattttat cgtgcagctg ctcgataaat tcgctggaat gatcggtcaa
    36841 cgcatcgcac acatccacca gccatccccc gcaatcggtc ggacccgtgc cctcttccag
    36901 atcgcttacc acatcgtcca gcgccagcac tttgcgttgt cgggtcgaaa caattaaccg
    36961 cccgtccata tatacacgca tggcgaccag ttgatcgggg cgttcatcgg tgctgccgtt
    37021 tatacagcgc aatgtaatca gcgtaccttc accgagacgg ctgactcggg gccgtgtgct
    37081 ctcgcccgcc agcgcatcac gtacgttatt gggaagcagc ggtgttgtcg ccagccattg
    37141 ggcgctatca tggtgtacat aattaaggtg gagccagcag ggatgcgctt catcaatcac
    37201 atctgtattt tccagcggtt taacgccgcc tctaccatcc agcatccagg caaatactgc
    37261 atccgggaca ttaacgtccg atcccttaat cgcttccaca gtgcctccat catcaacgca
    37321 ttattttgta gtctagcctt ctggccctgt tacgcaacat ctcatcaccc cattaccctg
    37381 aaatgattaa taaaattctg tctaaattga atacaaaaag caaaatgctt ttccgtatac
    37441 aaaccgtgtg aagtgttaaa tagcgtctat cattatcaga attatctgat catatgacgt
    37501 ggcttttttg cgatcggata gcaacaaaaa ttgataaaaa taacgggatc tcaatgatta
    37561 cgcacaactt caataccctg gacttactca ccagtcctgt ctggatcgtt tcgccctttg
    37621 aggaacagtt aatttatgcc aacagcgcgg cgcgactgtt gatgcaagac ctcacgttta
    37681 gtcagctacg aaccggtccc tattccgtct cctcacaaaa agaactgccg aaatacctct
    37741 ccgatctgca aaaccaacac gatattatcg aaatcctcac cgttcaacgt aaagaagagg
    37801 aaacagcatt aagctgtcgg cttgttttgc gagagctgac agaaacagaa ccggtgatta
    37861 ttttcgaagg tatcgaagcg ccggcaacgc tgggtttaaa agccagtcgc tcggcaaatt
    37921 atcagcgcaa aaaacaaggt ttttatgcgc gcttttttct gactaactct gcaccaatgt
    37981 tgttgattga cccctcacga gatggccaaa tcgttgatgc taacctcgcc gcgctcaatt
    38041 tctatggtta taaccatgaa acgatgtgcc agaaacatac ctgggaaata aatatgctcg
    38101 ggcgacgcgt catgcctatc atgcatgaaa tttcgcattt acccggtggc cataagcctt
    38161 tgaattttgt tcataaattg gcggatggtt cgactcgtca tgtgcagacc tatgctgggc
    38221 cgattgaaat ttatggcgac aagctcatgt tatgtattgt gcatgatatt actgagcaaa
    38281 aacggctgga ggagcagctg gaacatgctg cccaccatga cgcgatgacc ggattactga
    38341 atcggcgaca gttttatcac attaccgagc ctggccaaat gcagcacctc gccatcgctc
    38401 aggattacag cttattgctc atcgacaccg atcgttttaa acacattaac gatctctatg
    38461 ggcattctaa aggtgatgag gtgttatgcg ccctcgcccg caccctcgaa agttgcgctc
    38521 gcaaaggcga tttggtgttt cgttggggag gcgaagagtt tgtcttattg ctaccaagaa
    38581 ccccactgga taccgcgctt tcgctggctg aaactatccg cgtaagcgtg gcaaaagtga
    38641 gtatttcggg cttaccacgc tttaccgtca gcattggtgt ggcgcatcac gaaggaaatg
    38701 aaagcatcga tgagctgttt aaacgcgttg atgatgcttt gtatcgggcg aaaaatgatg
    38761 gacgcaaccg cgtgctggcg gcataagccg cggatgcgtc tcgagatcaa cgactgcgct
    38821 tagcgtggcg ctcccagttt tcttgctttg cctgtgccgt tttacgtagt gcgacgtaac
    38881 acgccccgct gccgccatga tgcggtagcg cggtacaata tgcctggaca tcatcaaatt
    38941 cggtcaacca gcgcgccaca tagctgcgga caatattggc atgcgattta tcttcccgcc
    39001 ctttaccatg aataatcagc acattacgca aaccatccgc cagggcttgt tgaatgaaac
    39061 tgaacaccat tttgcggcac tcttccaccg gctggcgcaa aagattcagg ctcgcctgtt
    39121 gcgggtattt accactgcgc agcttatcca gcaccccatg ttgcaaccct tcccgccgaa
    39181 actccagcgg ctgagttagc gggatgatgt cgagaaatcc agtggtgagg aaattatcaa
    39241 gttgcagcgt gtcgatacgc tgcggcgcac gttggttacg cgttggatgc cagtggacat
    39301 ctgtagcacg tttcagcggc tggacatctt ccatggcgtc aagaaacagc gatttgtcgt
    39361 caaggttcat gttacatcct cccgcaatta agagcgcgat atgataacca gaccgggctg
    39421 gtccaacaac gtattaccca aatttccagt aataagttcc aaatgttgcc gatattttaa
    39481 gcaaaatgct tatgcatgat tattcattca cgatattaat aatgtaactt atattttcgt
    39541 gaaatctgtc actgaagaaa attggcaact aaaggttaaa accgttataa cacagtcacc
    39601 ggcgcagagg agaccatgcc ggatttaaga cgcggatgca ctgctgtgtg tactgtagag
    39661 tctggcggat gtcgacagac tctatttttt tatgcagttt taactttgca gatagccgca
    39721 ttctcgccgg aattgcgtga ttaatgacgc ggtcagtggt gtctggcgac tatcacgccg
    39781 ctgaatcaaa taataggccg ctttcggtaa aatttcgcta accggcaaca tcaccagccc
    39841 ctgtccgtgc aagggatcgc agcccatttc ttcaggtagt atgctgagaa aatcgctttt
    39901 tgccaccaga ctgatacagg ctgagaacgt ctcgcagact acgccgacct gtggcgtttg
    39961 cgcctgatcg tcaagcaatt cactcaactg tttgtagtag ctgccgtgtg gcgtcggcat
    40021 tgtccagctg tagtccagta actgtttgat cgaacgggca ccaatggcgg gatgtcccgg
    40081 gcggcaaaag atcgcgaatt gcttttccag taatttctca aaagtaaatt cgtggtcgta
    40141 gggtccctga taataggtat tgatggtgaa atccagttct ccctggcgca attcattaat
    40201 catcgacacc agttgccctt ccataatgcg tacttttacc tgcggatgct gctgatgaaa
    40261 acgagatatg acagctggca tcagactgcg ggaaatactg gcccccatgc cgatattaat
    40321 ttgccctgcc agttgccctt gtcgttggcg aatatcctct tgcgctgcgc gcagctcttc
    40381 aagaataaga ctggcgtgct gataaaaact ttcaccggca tcagttaacg tcacgccttt
    40441 actacggcga aaaaagagtt gtgccgccaa cccttcttcc agttcctgaa tagatttact
    40501 cagtgccggt tgcgacatat tcaacattcg gctcgctccg cgaatgctgc cctgacgagc
    40561 cacttcaaca aaagcccgaa tttgatgaat ttttacctga aaagccatga cgccaccgat
    40621 aaccgttatt tatcagacca aagaaactgg catctacttt aatgcagatg attgtgtcag
    40681 ggtaatttat gaacggttaa aactgtgaaa aatcagttag tgataagtaa aaactatcgc
    40741 tacgtgaacc gggtcacact ttttactgat gacgggaaag gttatggagt ctttgaatca
    40801 atttattaat tcgcttgccc caaaattatc gcactggcga cgtgattttc accactatgc
    40861 agagtctggc tgggtggaat tccgcactgc caccgttgtt gcggaagaat tgcaccagct
    40921 cggttattca ctggcgctgg gccgcgaagt cgttaatgaa agtagccgga tgggattacc
    40981 tgatgaattc actctacaac gcgaattcga gcgcgctcgt caacaggggg cgctagaaca
    41041 atggattgcg gcttttgaag gcggtttcac tggcatcgtc gctaccctgg atactggtcg
    41101 ccccggtccg gtgatggctt tccgtgtcga tatggacgcg ctggatctca gtgaagagca
    41161 agatgtcagc catcgcccct accgcgacgg ttttgcgtca tgtaacgccg gaatgatgca
    41221 tgcctgtggt catgatggac ataccgccat tgggcttggg ctggcgcata cccttaaaca
    41281 gttcgagtcc ggactacatg gcgtcatcaa actgattttt caacctgcag aggaaggtac
    41341 gcgtggcgcg cgggcgatgg tcgatgcagg agtagtggat gatgttgatt attttactgc
    41401 cgttcacatt ggcactggcg tacctgcggg caccgtggtg tgcggcagtg ataattttat
    41461 ggcaaccacc aaatttgacg cgcacttcac cgggaccgcc gctcacgcag gcgcaaaacc
    41521 agaagacggt cacaatgcct tgttggctgc agcacaagca actcttgcac tgcatgcaat
    41581 cgccccgcac agcgaaggcg cttccagagt aaacgtgggc gttatgcagg caggaagcgg
    41641 tcgtaatgtt gttcccgcct cagcgttgct gaaagtggaa acacgcgggg ccagcgacgt
    41701 cattaatcaa tatgtttttg accgtgcaca acaagcgatt cagggcgcag caaccatgta
    41761 tggtgtcggc gttgaaactc gtctgatggg tgcagctacc gccagttctc cttcgccgca
    41821 atgggtcgca tggttgcaaa gtcaggcagc tcaggtcgcg ggggtcaatc aggcaattga
    41881 acgtgttgaa gcgcctgcgg gttccgaaga tgccacatta atgatggccc gcgtgcagca
    41941 acatcaaggg caagcctcct atatggtgtt tggcacacag ctggcggcag gtcaccacaa
    42001 cgaaaaattc gattttgacg agcaggttct cactattgcc gtcgaaacgc tggcgcgcac
    42061 cgcgctcaat tttccctgaa cgcgaggtat ctgatgcagg aaatctatcg ttttatcgac
    42121 gatgcgattg aagccgatcg ccaacgttat accgatattg ccgatcaaat ctgggatcat
    42181 ccagaaacac gttttgaaga gttctggtca gcggagcatc tggcttcggc gctggaatct
    42241 tcaggcttca tcgttacccg caacgtaggc aatatcccaa atgcctttat tgcttcgttt
    42301 ggtcaaggca aaccggttat cgccctgctg ggggaatatg acgccctggc aggtttaagt
    42361 cagcaagcaa gttgcgcgca acctacatcc gcgacgcccg gtgaaaatgg tcacggttgc
    42421 ggacacaatt tgctgggaac cgccgccttt gccgctgcaa tagccgtcaa gaaatggctg
    42481 gaacaatatg ggcaaggcgg cacggtgcgc ttttatggtt gtcctggcga agaaggcggc
    42541 tcgggtaaaa cgttcatggt ccgcgagggg gtatttgatg atgtggatgc ggcactcacc
    42601 tggcacccgg aagcctttgc cggtatgttc aatacccgca cgctggcaaa cattcaggca
    42661 tcatggcgct ttaaagggat cgcagcacat gccgcgaatt cccctcattt gggacgcagc
    42721 gcccttgatg ccgtaacgtt gatgaccact ggcaccaact tcctcaacga acatattatt
    42781 gaaaaagcgc gcgtacacta tgccatcaca gatagcggcg ggatctcgcc caacgtggtc
    42841 caggcgcagg cagaagtgct ttatcttatc cgcgcccccg aaatgaccga tgtgcagcat
    42901 atttatgatc gggtcgccaa aatcgccgaa ggtgcggcat tgatgaccga aaccacggtt
    42961 gaatgccgct tcgacaaagc ctgttccagt tatctcccga atcgcacctt agaaaatgcc
    43021 atgtaccgag ccctatccca ttttggtacc ccggaatgga actgcgaaga actggctttt
    43081 gcgaaacaaa ttcaggctac gctcaccccc aacgatcggc aaaacagttt gaacaatatc
    43141 gctgcaaccg gtggcgaaaa cggcaaggct tttgcactac gtcatcgtga aacggtactg
    43201 gcgaatgaag tcgctccata tgccgccacc gataacgtgc ttgcggcatc gactgatgtc
    43261 ggcgacgtca gttggaaact gcctgttgcc cagtgtttca gcccctgctt tgccgtcggt
    43321 accccgctac atacgtggca actggttagc caggggcgaa catctattgc tcataaagga
    43381 atgctgctgg cggcgaaaac tatggcagca accacactta atctcttcat tgattcaggg
    43441 ctattgcaag aatgccaaca agagcatcag caagttacgg acacgcaacc gtatcactgc
    43501 cctatcccga aaaacgtgac accgtcacct ttaaaataac aacaacaacg caaacacaac
    43561 aaacgaggaa tgcccatgag tatgtcatcc ataccgtcgt cctcccaatc cgggaagctc
    43621 tatggctggg tcgaaagaat tggtaacaag gttccccatc cttttttgct ctttatctat
    43681 ttgattatcg tactcatggt gacgacggca attttgtcgg cctttggcgt cagtgcgaaa
    43741 aacccgaccg atggtacgcc agtggtcgtg aaaaacctgc tcagtgtgga aggattacac
    43801 tggtttttac ccaatgttat taaaaacttt agcggttttg ctccacttgg cgcgatcctg
    43861 gcgctggttt taggtgccgg tctggcggag cgcgtcggct tactgccagc gttgatggtt
    43921 aaaatggcat cgcatgtgaa tgcccgctac gccagttata tggtgctgtt tattgctttt
    43981 ttcagccaca tttcttccga tgcggcgtta gtgatcatgc caccgatggg tgcgctaatt
    44041 tttctggcgg tgggcaggca tccagttgca ggtttacttg ccgccattgc aggcgtaggt
    44101 tgcggcttta cggctaattt actgattgtc acaaccgacg tgttgctgtc ggggatcagc
    44161 acggaggctg cggctgcgtt caatccgcaa atgcacgtca gtgtaattga taactggtat
    44221 tttatggcca gctccgtagt cgtactgacg attgttggcg gcctgataac cgacaaaatc
    44281 attgagccac gtttaggtca atggcaggga aacagcgatg agaaactgca gacattgacc
    44341 gaaagtcagc gttttggttt acacatagca ggtgtcgtat cgctactttt tattgctgcg
    44401 attgcgctga tggtgatccc ggaaaacggg atattgcgcg atccgattaa tcacaccgtg
    44461 atgccatcac cctttattaa aggtatcgtg ccactgatca ttcttttttt ctttgtggtc
    44521 tcgctggctt atggcatcgc tacccgcaca attcgacgtc aggcggattt accgcattta
    44581 atgattgaac cgatgaaaga gatggcggga tttatcgtga tggtttttcc cctcgcccag
    44641 tttgtcgcca tgtttaactg gagcaacatg gggaaattca tcgccgtggg gctgaccgat
    44701 atactggaaa gttcagggct tagcggcatc ccggcgtttg tcggtctggc gttgctttcc
    44761 tctttcttat gcatgtttat cgccagcggt tccgcaatct ggtcgattct ggcccccatt
    44821 ttcgtaccaa tgtttatgct acttggcttt cacccggcat ttgcgcaaat cctctttcgt
    44881 attgccgact catccgtatt gcctttagcg ccggtatctc cttttgttcc actgtttctt
    44941 ggattcctgc aacgttacaa accagacgcg aaactgggta cttactattc gttagttttg
    45001 ccctatccac ttatcttttt ggtggtatgg ctgctgatgt tgctggcgtg gtatcttgtt
    45061 ggtctgccga taggtccggg gatttaccca cgtttgtctt aagagagaac ggatgctgag
    45121 attacttgaa gaaaaaattg tcacgccact gggtccactg tgggtgattt gcgatgagca
    45181 atttcgcctg cgggcggttg aatgggaaga gtacagcgaa cgcatggtgc agctgctgga
    45241 catccattat cgcaaagaag gctatgagcg catttctgcc accaacccag gtggtttaag
    45301 cgacaagctt cgtgaatatt ttgccggtaa tcttagcatt attgatacgc ttcccactgc
    45361 cacggggggg acgccatttc agcgcgaagt ctggaaaaca ttacgcacaa tcccctgcgg
    45421 gcaggtaatg cattacggcc aactggctga acaattgggc cgccccggtg cggcgcgtgc
    45481 cgtaggtgcg gcaaatggat cgaatcccat cagcattgtt gtgccttgtc atcgggtcat
    45541 tggcagaaac ggtaccatga ccggatatgc aggcggagtt cagcgaaaag agtggttatt
    45601 gcgccacgaa ggttatcttt tgctgtaaac attaaacaat ttgtgccagc ttgttcacac
    45661 ttttatgtaa agttaccctt aacaacttaa gggttttcaa atagatagac atatatttac
    45721 atctaatatc ggaattctct gctgttaagg tttgcttaga cttacttgct ccctaaaaag
    45781 atgttaaaat tgacaaatat caattacggc ttgagcagac ctatgatccc ggaaaagcga
    45841 attatacggc gcattcagtc tggcggttgt gctatccatt gccaggattg cagcatcagc
    45901 cagctttgca tcccgttcac actcaacgaa catgagcttg atcagcttga taatatcatt
    45961 gagcggaaga agcctattca gaaaggccag acgctgttta aggctggtga tgaacttaaa
    46021 tcgctttatg ccatccgctc cggtacgatt aaaagttata ccatcactga gcaaggcgac
    46081 gagcaaatca ctggtttcca tttagcaggc gacctggtgg gatttgacgc tatcggcagc
    46141 ggtcatcacc cgagcttcgc tcaggcgctg gaaacctcga tggtatgtga aatcccgttc
    46201 gaaacgctgg acgatttgtc cggtaaaatg ccgaatctgc gtcagcagat gatgcgtctg
    46261 atgagcggtg aaatcaaagg cgatcaggac atgatcctgc tgttgtcgaa gaaaaatgcc
    46321 gaggaacgtc tggctgcatt catctacaac ctgtcccgtc gttttgccca acgcggcttc
    46381 tcccctcgtg aattccgcct gacgatgact cgtggtgata tcggtaacta tctgggcctg
    46441 acagttgaaa ccatcagccg tctgctgggt cgcttccaga aaagcggtat gctggcagtc
    46501 aaaggtaaat acatcactat cgaaaataac gatgcgctgg cccagcttgc tggtcacacg
    46561 cgtaacgttg cctgattctt ccgcataact cactatcctt ctgtcatatc attaaatttt
    46621 tctgatttat tgatctgaca gaaggttcat cactgtttca ttcaccagat atgggttaat
    46681 cttttaatta caaactgcgt tgacagttgt tgtaaggaga ccctgtatgg ctatgtatca
    46741 gaacatgctc gttgttatcg atcctaacca ggacgaccaa ccagcattgc ggcgagctgt
    46801 ttatttacat caacggattg gtggcaaaat taaagccttt ttgccgatct atgacttctc
    46861 atacgaaatg accaccctgc tctctccgga cgaacgtacc gctatgcgtc agggcgtcat
    46921 cagccagcgt acagcctgga tccacgagca ggcaaaatat tatctcaatg ctggcgttcc
    46981 cattgaaatt aaagtggtct ggcataaccg tcctttcgaa gccatcattc aggaagtgat
    47041 cagcggcggg cacgatttgg tgctaaaaat ggcgcaccaa catgaccgtc tggaagcggt
    47101 gatttttacg ccaacggact ggcatctgtt acgcaaatgc ccaagccccg tgtggatggt
    47161 gaaagaccag ccgtggccgg aagggggtaa ggcgctggtg gcggtgaatc tcgccagtga
    47221 agagccgtac cataatgcgc tcaatgaaaa actggtcaaa gagacgatcg aactggcgga
    47281 acaagtcaac cataccgaag ttcatctggt tggcgcttat ccggtaacgc caattaatat
    47341 cgcgattgaa ctgccggaat ttgatccgag cgtttataac gatgccattc gtgggcaaca
    47401 tttgctggca atgaaagccc tgcggcagaa attcggcatt aatgaaaaca tgacgcacgt
    47461 agaaaaaggt ctgcccgaag aggtgattcc tgatttggcg gagcacttac aggcggggat
    47521 tgtggttctg ggcacggtcg gacgcaccgg tatttcagca gcattccttg gcaacacggc
    47581 ggaacaggtg attgatcatc ttcgctgcga cctgctggtc attaaacctg accagtatca
    47641 gacacccgtt gaactggatg acgaagaaga cgattaacga ctcttcaata actgacaagg
    47701 cccgagttat cgggcctatt ttttacttac tgctcttcgc cgccaagaaa ataaattccc
    47761 aacggtattg ccagcaacac agtaaagacc aggctataaa caaaaatcat cgatgactga
    47821 atcacataca ttgatgtcgt ccactcagac agcggaatat tgtactgttc tataacgccg
    47881 ccgatggtcg cgcgagtcac aaccgacgcc gcaataatga aaaccgccaa caaaccaaag
    47941 agaaatttct tccctttcgc tgacttcagt ttcgccataa tcatgatgta atccttgtgc
    48001 agacaaattt cttgttacct aaacgtaaca ataccatgac atttcaccgt tgtctgctct
    48061 gaaaacctca cctcttagct ggatttacaa tcaacgtatt gattagttag ctaatgttgc
    48121 tacttccttc cctgactatt gatgatctga atgaattgtc gcggtaaaat agtcccgcca
    48181 ggggtttccg gcatgacgac aattatctgg aggagcctga taaaacaatg atcgctgaac
    48241 tgtttacaaa taatgcgctt aatctggtca ttattttcgg tagctgcgca gcattgattc
    48301 tgatgagctt ttggtttcgc cgtggaaatc gtaaaagaaa aggattttta ttccatgcgg
    48361 tgcaattttt aatctacacc ataattatta gtgctgttgg tagcatcatt aactatgtta
    48421 tagaaaacta taaactcaaa tttatcaccc caggcgttat cgattttatc tgtacgtccc
    48481 tgattgcggt tattctgacg attaagctat ttctgctgat taatcagttt gaaaaacagc
    48541 agattaaaaa aggtcgcgat atcaccagtg cgcggatcat gtcgcgcatt atcaaaatca
    48601 ccattattgt ggtgcttgtt ctgctttatg gcgaacattt cggcatgagc ctttctggct
    48661 tgttgacctt tggtggtatt ggtggtctgg ctgtcggtat ggccggtaaa gatattttga
    48721 gtaacttctt ttccgggatt atgctctatt tcgaccgtcc ttttagtatt ggcgactgga
    48781 tccgttcacc ggacagaaat atcgaaggta cagtagcgga aattggctgg cgaattacca
    48841 aaattacgac ttttgataat cgtccgttgt acgtaccgaa ctcgttgttt tcgtcaatca
    48901 gcgtagaaaa cccaggacga atgaccaacc ggcgcattac cacgaccatt ggtttacgtt
    48961 atgaggatgc ggcaaaagtg ggcgttattg tcgaagccgt acgtgagatg ctgaaaaatc
    49021 acccggccat cgaccagcga caaaccttac tggtttattt caaccagttt gctgactcct
    49081 cattgaatat tatggtttat tgctttacca aaaccacggt atgggctgaa tggcttgctg
    49141 cacagcaaga cgtttatttg aagattatcg atattgtaca gtcacacggt gcggactttg
    49201 ccttccccag ccagacgctg tatatggata acattacacc gccggaccag ggtcgctaaa
    49261 tcagacatca ctggcgttat ccacaagggt aacgccagtt ctcatcacat caatgcttca
    49321 caatatacat agtccgactg tacgccacat cttcagggtt attaatggga taacctttca
    49381 gccacggctt gattaatcgt ccattggtat attgataaat tggtgcaatc ggtgcttgct
    49441 ccatgaggat tttttctgcc gcgttgtaat cggcattacg cgctttaacg gtattttccg
    49501 tcgatgcctg ggccagaact ttgtcatatg ccggattgtt aaagcgtgaa atattcccgg
    49561 aatgcgttga cgttaataat gtcaggaaag tggagggttc attataatcc cctacccacg
    49621 aggcgcggat aacatcaaaa ttgccggtgt tacggctatc gatataggtt ttccattcct
    49681 gattttgcaa tttaacatct acgccaaggt tctttttcca cattgatgct acagcaatcg
    49741 caattttttg atggttttct gaagtgttat acaaaagcgt cagcttcagc ggtttttgcg
    49801 gaccataacc agctgcgctc aacaaagttt ttgcctgcgc attcagttct tcctgactca
    49861 tttgttcaaa cggcgaaggt tccggcgtaa atcccgcggt aacatctggt gtaaaatgcc
    49921 acgctggctt ttcgcccgtc cctaatactt tttcggtcat caggcggcga tctatcgtca
    49981 tacttaatgc caggcgaacg cgctgatctg ccgtcggccc tttttgcgtg ttaaacgcat
    50041 aataataggt cccgagctgc ggcggcgtat aaacctgccc cggaatatcc ttcaacagct
    50101 tctgatacat atttttcggg aaggattcag tgatatcaat atcccccgcg aggtaacgct
    50161 tagtggctgc ggattcctga ttaattggca ggaaggtcac tttttgcagt accgttttgg
    50221 cgttatccca ataatgggta ttcggcacta cgaccagttt ttcattgact acgcgctctt
    50281 taagaacata agcgccattg ccgatcagat ttccgggttt cgtccactct ttactgcttt
    50341 ctacgttggc tttttgcacc gggaagaagg caaagttagc ggttaaattc acaaaccacg
    50401 gcaacggttt atcaagctgg attttcaaag tatgggcatc aactgcggtg acgccaagct
    50461 ggtcaggcgt ggctttacca tcaataatcg cctgtgcgtt gttgattccc gccagcgcgg
    50521 caaaccatgc aaatggcgac aatgtttttg ggtccaccag acgttgccag ctgtagacaa
    50581 aatcttgcgc cgttaccgga gtgccatccg cccattttgc gttatcgcgc agggtaaatg
    50641 tccagatacg gttgtcatta cttttccact gagtcgcaac gccggggaca atctcccctt
    50701 tctcgttctg attcaccagt ccttcaaaca gatcgcgaat gacctgaatc tctggcaggc
    50761 ccacggcttt agcgggatcc agcgacgcag gctcatcttt aatgtggcgc accagctcct
    50821 gcttctctgc cagtactgtg ccgctcggaa cttcagcagc atacgaaaga gaaatgctgc
    50881 tgaccaacag cgcacaacac gtgactgaaa cagagtgctt cataagtttc cctctaaccg
    50941 acattaaaat tgatgcgtaa ttatttgttt cgccttaaag aaatgcaaac aacttccggc
    51001 aaaaaagtga tacaagatcg ataacatagc gttgaagaaa aggatttgat aatccgcaaa
    51061 atttgcacaa cactgcctgt aatacttcct gaaccagaga cgatcatgac cgtaactcgc
    51121 ccacgcgccg aacgcggcgc atttccgccc ggtacagaac attacggacg ttcattattg
    51181 ggcgcgcctt tgatctggtt tccggcccca gccgccagtc acgaaagtgg tttgattctg
    51241 gctggcactc acggtgatga aaactcttcg atcgtcacgc tctcctgtgc tctgcggact
    51301 ttgacaccgt ctttgcgccg ccatcatgtg gtgctgtgtg tgaatcctga cggctgccag
    51361 ttagggttac gggccaatgc taatggtgtg gatttaaacc gaaactttcc ggcagcgaac
    51421 tggaaggaag gtgaaacagt ttatcgctgg aacagcaccg ctgaagaacg tgatgtcgtt
    51481 ttactgacag gtgacaaacc tggctccgaa cctgaaactc aggcgctgtg ccagcttata
    51541 caccgcattc aacctgcctg ggtggtctca ttccacgatc cactggcctg tattgaagac
    51601 cccagacaca gcgaattagg tgaatggctg gcccaggcgt ttgaattgcc actggtaacc
    51661 agcgtcggtt atgaaacgcc tggctctttc ggcagttggt gtgcggatct caacctgcat
    51721 tgcatcaccg cagagtttcc gcccatctcc tccgacgaag ccagcgaaaa atatctcttt
    51781 gcgatggcaa acttgctgcg ctggcatcct aaagatgcaa ttcgcccgtt gtgaactgaa
    51841 gcgccggttc cacatctacc gccagccagg tcggtccgtc aagatcggcg aaactgacct
    51901 gcggcaccag cggtaaagcg gcgctaatgg cccgagaggt acacaacatg cagcccagca
    51961 tcagacgaaa accttgtgca cgcgcttcag tcgccagcgc cagcgcttcc gtcagaccac
    52021 cggttttatc aagcttaatg ttaaccatct catagcgccc tttcagcgcc ttcagattgc
    52081 tacgagtatg acaactttca tcagcacaaa tcggtaacgg atgaataaaa ttctccagcg
    52141 ccgcatcgtc ctgcgcagaa agcggttgtt caagcatcgc aacgcctaaa tctgccaata
    52201 gctggcaacg cgccgccaac ccttctgcac gccaggattc atttgcatca acgatcagcg
    52261 tcgcatcggg cacagctgtg cgaattgcca ccatccgctc actgataaga tggttatcca
    52321 gcttcacttt cagtaatttc gcgcctgcct gccagagtgt tgatgcacta ttggccatct
    52381 gatcaggcgt accgatgact atcgtctgtg ccgtggtgac tgtctcggga agcgttatgc
    52441 cgatcaaatc agccagcgat tgctgctgtt ttcgcgccgc cagatcccac aatgcacaat
    52501 ccagcgcatt acgtgctgcg ccggcaggga ggattttttg caactcctcc cgtgtcagcc
    52561 ctttctctaa ttgcggcacg acgctcataa tttgcgccat taccgaggca tcactttcgc
    52621 catagcgcgg ataaggcgta cattcgcccg tacctttgac gccatcttct tccagttcaa
    52681 ccaccaccac gcgcgcttca ctgcgacttc cccgggcaat cacaaacggg gtatgtaagg
    52741 gccaggcctc ctcaaatacc ttaacggttc tcatctttac tccttgttgt cgcggtggtc
    52801 tgcggattaa gcgcaaatag cgtttgctgt gttattgaca gttagcataa actaggtgtg
    52861 acgttaacta tatgtaaaca ggaaagataa tcatgtcaca aaccgttcat ttccagggca
    52921 acccggttac agtcgccaat tccatcccgc aggcgggtag caaagcgcag acttttactc
    52981 tcgtggcaaa agatctgtct gacgtcaccc tcggtcagtt tgcgggtaaa cgcaaagtgc
    53041 tgaacatttt cccgagtatt gataccggtg tttgcgccgc atcagtacgt aagtttaacc
    53101 aactggcaac cgagatcgac aacaccgttg tgctgtgtat ctctgccgat ctgccattcg
    53161 cccagtctcg tttctgcggc gcagaaggtc tgaacaacgt tatcaccctc tccactttcc
    53221 gtaacgctga attcctgcaa gcctacggtg tggcaattgc tgatggccca ctgaaaggtc
    53281 tggcagcgcg tgccgttgtg gttattgatg aaaatgacaa tgtgattttc agccagctgg
    53341 tggatgaaat caccaccgag ccggattacg aagcagctct ggctgtactg aaagcataag
    53401 ttaatatgcc tgatggtgtt gcaccatcag gcatattcac gcttactctt cgttcttctt
    53461 ctgactcaga ccatattccc gcaacttatt ggcaatcgcg gtatgtgaaa cgccgagacg
    53521 ttttgccagt ttgcgcgtgc tgggataatt gcgataaagc tgggttaata ccgagcgttc
    53581 aaaacggctg gtgatttcgt ccagcgaacc ttccatcgca tcttcgccca cggctaccgt
    53641 tgcggcgtca taatccggca acaaaatatc ctgtggacgc agctcataac cgtccagttg
    53701 tgtcagtgca cgatagatag cgttctttaa ctgccgcaca tttcccggcc acgcataacg
    53761 cgtaagtaca gtattcagat cagcggccag tttcggacgc ggcacgccct gctcgtcggc
    53821 aaagcgggcg acgaacagct cggttaacgg catgatgtcc tgcggacagt cacgtagcgg
    53881 cggcagattg agcgtcaaca cgttcagacg ataatagaga tcttcacgga acacgccttt
    53941 ttgcaccagt tcgaccagat tcttctgcgt agcacaaatc acccgcacat cgacatgcac
    54001 ctcatggtct tcgccaaccc gacggaaggt gccatcatta aggaaacgca gtaatttcgc
    54061 ctgcatccgt ggtgacattt cccctatttc atccaacagc accgaaccac cgttcgcctg
    54121 ctcaaagaac cctttcttcc cttccggagc atgaccaaac agttcactct cgaccgcatc
    54181 ttccggtata gacgcacagt tcagcgccag gtaaggtttg ctcgctctgg ggcttgcctg
    54241 atgacaggcg taggcaaaga gatcttttcc ggtgccggta tcacccgtaa tcagcagtgg
    54301 cgcgcttagc atcgccagtt tctgcgcctg ttcgacaaca tgcttcattt tcgggctgac
    54361 ggcgacaatt tgactaaagg cgctgacgtc ctgggcagcg acattttgca actgacggcc
    54421 catacgaatc gttgatcgca gcatcaccac cgcaccggtc aggacgtgtt gatcattttc
    54481 atcctgaaga taaacaggcg taatctccat caggaaattc tgcccattaa taacgacatg
    54541 ctcgttatgc gaatcttgcg gttcgctttc cagccagcgt aaaaaattaa agccgttaat
    54601 caattgcgcg gcggtatggt tgcgcaggcg atccaatttt tgcccaaaaa gctgacagct
    54661 cgccgggttc gccatatcca ctttgctttt catatcgaca gagagcacag gttcaggcaa
    54721 tgcctccagt aacgcgctca acgccagatg ctcacgttcg gaaggcatcc acgggacagt
    54781 acgcacatcg gtaacacctg caatacggcg tatttcggcc atcagactgc tgaaactctc
    54841 aaactccagt tcagcaaaat tgaggtagat tcgcccaatg ggatcaatct caataccgcg
    54901 taaatcaatg cctcttagca cgagtagatc gagtaattcg cgggtcagac cgagtcggtc
    54961 ttcacaaaag acttccagac gcatgggaac cttcacctga aaaaagaaca attaatatga
    55021 tgatatgaca ctatttgaat agcaggaagg tttctgtcaa caatcattga cacaaagacg
    55081 gaaaaacggg cacttcggcg taaagatatc cggtcagcac ccgatattgc attatttttc
    55141 gctgggcgtt ttgccttttt gcagagtttc tttcacctga ccgataagct gacgacggaa
    55201 atccccgagg cgtggcttgt catcgtcaat ccacggcagc gggcggcaaa gctccatagc
    55261 tttaatcccc agtcgtgccg tcagaagtcc tgcaccaatc ccctgagctg cgcgggtaga
    55321 caaacgagca gcgagatctt gcgacatcca gtccatcccc acttcgcgca ccagttcgct
    55381 ggctccggcg aaagcgatat tcagcaatac cagcttgaac aggcgcaaac ggctgtaata
    55441 ccccagttca atgccataca gcgtggcgat gcgattaatc aaacgcagat tgcgccaggc
    55501 gataaatgcc atatccacca gcgccagcgg gctgaccgca atcatcaatg ttgattccgc
    55561 tgccgaacgg ctgatttcgc gccgtgcctg ggcatctaaa actggctgga ccaaatgcgc
    55621 atacaaactg accacttcac ggtcgttttg cgtttcatgg attgaggcat accagcgttg
    55681 cagcgccgga tgtgactgat cgatgcccgc ctgctgcgcc agtttttcgc aaaatgcgcg
    55741 gcctttgccg gtgccatggc tgtgcaataa atcacgcgct tcgtcgcgtt catgggcgcg
    55801 ctgtcgcaag cgccataagc gccgccactc tgttaccaca gaacctacgc cagcgccgat
    55861 aatcaatgcc cctgcggcac atccacccag cgctacccag tcctgggttt gccaggcatt
    55921 cattgtccac tgtaccccct gcccgacaac gcttgcgcca aacagagcca gcccgcccat
    55981 caccattttg cgccacaggc tgcgtttcgg acgtaacgct gcgtccatca ccgcttcaac
    56041 ttgcccctct tcttcctgcg cttcgtcgag cgtggccggg gcaaaatttt gcgcctgatt
    56101 ttcgtcaaag gtctgctgcg ccctgaattc aggattctga tcgacatcca gcggaccgtc
    56161 gaaatcaata cgtggtttta acggttcggt catcgcaatt tatctcctat taaaaattcc
    56221 agcgcagcat caaggcgaat atgcggcagc ggtttgtcaa catccatcac ctgcggacga
    56281 aacgcctcaa actggaagcc ttgcttatcc cagaacgcct gaccgggcaa acgagcggga
    56341 acttcgccag gataaacagt gagcggtgcg ccatcgctga gtcgattacc gcgcagcgcc
    56401 gggattttct caccgttaac atcaataatg ccgctggtgg tcgcctgaac tgacgccagc
    56461 cccaggcagt ccatgctgat cccttcgaac gccgcatttt gccaggcatc ctgaatcagt
    56521 tgttgcagta atgaaaccat attggcgtgc tgatcgatgg tcacatggtc tgctttagtg
    56581 gcagcaaaca atagcttatc gataaccggt gaaaacaaac gccggaacag ggttcgctgc
    56641 ccgtagtgaa aactttgcat cagttgcgtc agcgccagac gcatatcatt aaatgcctgt
    56701 ggcccactgt tgagaggttg caggcagtcc accagcacaa tctggcggtc aaagcgcaga
    56761 aaatgattct tatagaaccc cttcaccact ttctcgcagt aataattaaa ccgctcgcgc
    56821 aacattccgg cattggtgtg cttatcggcc tgcgccagtt tggactcgcc ccaggcatcg
    56881 acatctggcc acgggaagaa ttgcagcgcg ggcgcacctg ccatatctcc cggcaagaca
    56941 aagcgcccag gctgaataaa gtgcagcccc tgctgtttac agtggtggag ataatcggtc
    57001 cacgcggcgg caatgtctgc cagccggttt tcgtcggcag gcgctagcgg gtccagccct
    57061 tcgcacatca ttcgccattt cgccgaccat tcgccgcgct gaccattaag taagcccgtc
    57121 atctggcgcg accagcttaa atagtcctgc gccagcatcg gcaggtcgag caaccattcg
    57181 ccgggataat ccacaatctc cagatacagc gtggaggtat ccttaaagtg gcgtagcagc
    57241 gaatcgttcg atttaaaacg tagcgccagg cgaatttcgc tgacgccgcg cgttggcgtt
    57301 ggccaggcgg gtggatcgcc atataactgc gccagccctt catcataggt gaagcgcgga
    57361 atgccaaagt cacgctgggg aatgcgtttt acgcccagca gccgttcttc acgcaccgcg
    57421 cttaacagcg gcaaccttgc tccggcgtga atattgagca actgattgac catcgcagtg
    57481 ataaacgccg ttttgccgct gcggctaagt ccggttacgg cgaggcgcag atgtctgtcg
    57541 acaccccgat tcaccagcgc attaagttca tttttaagtc gcttcattgc tgtcctgtgc
    57601 tgctctgaag accagaaaaa aatcattcgt aagaatatga atgtgggggc caggccattg
    57661 attatcaact gcccgtgttg tcatcgacgg gcgaactcca taagatgtgc aacattcacg
    57721 ttcggacgga gttcctgacc tatgtcccct actatttatg atattgccag ggttgcaggc
    57781 gtatcaaaat ccaccgtatc acgcgtgctg aataagcaaa ccaatatctc cccggaagcg
    57841 cgcgaaaaag tgttacgggc cattgaagaa ttacagtatc aaccaaacaa gctggcacgc
    57901 gcgctgacct cttcgggttt tgatgccatt atggtgattt ctacccgttc gaccaaaact
    57961 acggcgggta atccgttttt ctctgaagtt ttgcatgcca tcaccgccaa agcggaagaa
    58021 gaaggtttcg acgtgatatt acaaacgtcg cacaatccgg cagaagatct gcaaaaatgc
    58081 gaaagcaaaa ttaagcagaa aatgattaaa ggcattatta tgctaagttc gcctgccgat
    58141 gaatccttct ttgcacaact cgacaaatac gagatcccgg tagtggtaat tggcaaagtt
    58201 gaaggtcaat acagccatgt ttattccgtc gataccgata attatggcga cagtattgcg
    58261 ctgaccaatg cgttaattga aagcgggcat aagaatattg cctgcctgca tgcgccgctt
    58321 gatgttcatg tttcagtgga tcgggtaaat ggttataagc aaagcctggc tacgcataat
    58381 attgcagtgc gtgatgaatg gattgttgac ggcggttata cccatgaaac agccttgcaa
    58441 gccgcacggg aattattaag ccagtcaccg ttgcctgagg cagtgtttgc tactgacagc
    58501 ctgaaattaa tgagtattta tcgtgcggcg gcagagaaaa acattgctat tccgcagcag
    58561 ttagcggtgg tgggttatag taatgaaacg ctgtcgttta tattaacgcc tgcaccaggc
    58621 ggcatcgatg ttccgacgca ggagttaggt caacaaagct gcgagttatt attccagcta
    58681 attgccggaa aaccgtcacc acaaaatatt accgttgcta cgcatatgtc gttgaaataa
    58741 atgtatgccg gatttagcgc tcgcgccgca tccggcaatt taacccatta tcagaacgag
    58801 taatttacgc cgacacctgc ataatggaat ttatcgctgt cgccttcgtc gtgatcctgc
    58861 cactcaaacg cgtattccag cgaaacggaa agaccattct ggaaatcata accgtaaaat
    58921 aaccccacac ggttaaaatc atggccttca cgttcaatat catccagcca gtcccagtta
    58981 ctccagcgat ccagcccaat gcgcgtatac ggcgtcaccg agtggttgcc gagcgtcagc
    59041 ggcaaatagg cacgaatttc ttgcgtggaa aactcaccgt tattgcggct gtcgtccata
    59101 ttgaagccgc gctcgagata atagttcact cgcaaagcaa ccgtttcgtt gaaggtatat
    59161 tgcagacctg tttccgtttc gactcgggta tcagcgtaac cggtcgtgtt cagatcgttg
    59221 gcaaatttat acatcgataa ccaaccgttg aaacgtaaat cgtcagtcag tttcacatcc
    59281 cagtctggcg cgattttcca acgctgcata ttcgccgtgt ctttacccgg ttcatcaacg
    59341 tagtgataac cataattacg gaaaccacca gtcagaccga aactgaaatc atcgctttcg
    59401 aggaactgat aatgtacctc cagctccggg cgatcaaacc acgttccacg tttacccgcg
    59461 ctataatcta ccggcccttc ctgataatag gccagagaaa ttctccacgg cccgttggcg
    59521 gcattaaaat agacagaagg ctccgcgagc ccatccatat cttcgccata accttcgacg
    59581 ttttctattt cgtacatcgc gccgatatta aagtgccagt cgttcttttc ctcggcctgt
    59641 gcgcaagcca ttcccgcaca catcaccagt gcggtacagg gtaataactt tttcattatt
    59701 gttccttgta ttattctggg ggaatgcctt ccccctgtat ttagcgaatt gctatttccg
    59761 tttctgcatc aaagaaatga catttagtca tatcaaaatg aatagtgata ttttctcctg
    59821 catgataatc atttaacgca ccagcacgga ccactaactc gtgcccccca accgtggtgt
    59881 agagcataaa ttccgcaccg gttaattctg ccacgctaat tttggcggaa atgttatttt
    59941 cctcttgcgc gtccggatga atatcttccg ggcgtattcc catcacgatg ggcttatgca
    60001 aactttcctg tgttttcaga accgctaatt tctcttcggg tatggttaat ttaagcgttt
    60061 ccgtaacgaa tttatcgcca tcgatcgtgc cgcgaataaa attcatcgca ggcgatccaa
    60121 taaatccggc aacaaacata ttcgcaggtt ggttataaac cgttttcggc gcaccgacct
    60181 gctgaacaat cccatccttc ataatcacaa tccgcgtcgc catggtcatc gcttcggtct
    60241 gatcgtgggt cacgtagatc atggtggtgt tcagtttctg atgcagcttg ctgatctctg
    60301 cgcgcatttg tacgcgcagc ttggcatcaa ggttagagag cggttcatcc attaaaaaca
    60361 cgcccgcttc gcgcacaatc gcccgtccga gcgccacacg ctggcgttgc ccgccagaaa
    60421 gcgcgcccgg cttgcgtttc aggtactcac gcaggccgag gatttgcgcc gcccagttaa
    60481 cccgctcatc aatcacctct ttggcgattt tttgcatctt caggccaaac gccatgttgt
    60541 cgtagaccgt catatgcgga tacagcgcgt agttctggaa caccatcgcg atattgcgcg
    60601 ctttggctgg aacgtcattc attcgtttgc cgtcgatcaa cagatcgcca ccgctgatct
    60661 cctcaagccc ggcaatcatg cgcagcgtag tcgatttacc gcagcctgac ggaccgacaa
    60721 agacaatgaa ctctttatcg gcaatttcca ggttgaagtc cttcaccaca tgcacctggt
    60781 tatcgtagat tttttgaata tgttgtaacg aaagctgagc catgttgatt cctttgctat
    60841 acgttttgcc agaaggccga taaccgcgac catgtgagag attccgttga gggcaacagc
    60901 aattgcgccc cggttaagcc cgcgccgatc cccaccgagc gcataccgct ggcgttaatg
    60961 gcttcaatgc ccgcctgcgc atcttcaatg ccgatacatg cctgtggcgg cacgcccagc
    61021 cctgcacagg cggcgagaaa gatttccggg tccggtttcg aatttttgag ttgggaagcg
    61081 tccgcgcaga aggtgaaaaa ctcgcgcagc tccagcgctg ctaaaatcgt cggcgcattc
    61141 agggagacag aagccagccc aaccggaatc tgctgtgctc ggagctctac cagcaaattg
    61201 tgaatgccag gcagcacagc attaaccgtc agttcgcgca gtgagtggac gtaaagcaga
    61261 tttttgcgat acgccagttg cgcccgttcc tgtgggttaa aatcgccctc tttacccccg
    61321 tgctgcagaa ttcgccgcag ggactcatcg cggctgatcc cttttaggaa ttcgttaaac
    61381 tgcgcatcaa tgctgatgcc aatttcagcg gcaatctgct gccacgcctg gaaatgcaga
    61441 tgtgcggtat cggtgattac tccatccaga tcgaaaatta ccccttgcag tttcattcac
    61501 cctcctgatg cgtggtagcg gtcccattga agggcaaaat aaaatcccct aaacagaaaa
    61561 cagattcttc agagactgaa ataagctgac cgttcaaacg cagtgaaact ggcgcagaag
    61621 tccgaatcgc aatgcgctgc gcgtcaagag tgacctgtaa ttcacagccc tgccagaaca
    61681 gagggaaaga caactgttgc cactgctcag gtaacgccgg attgagatgt aattcaccgt
    61741 tgcgcacgct cgccccggca aaaccctgaa tcgcccccaa ccagattgcg ccagttgcgg
    61801 cagcgtggat accgtcatca cagctatgcg gatcagcacc aagatcgatt tcagtcccct
    61861 cccgccagaa ctgataactt tgcgccaaca ggccacagcg tgcggcaaca atgccgtgga
    61921 tcgctttact cagtgaagag tcgtgaatgg tgcgcggttc ataaaattgc agattggcaa
    61981 gacacgatgc cgctgagtac tgctccggca gcatgtaatt gagcatcacc acatcagctt
    62041 gtttgaggat ctgcatctcg ttcacttctg cgcgtgaata atccagcaga atggtttgct
    62101 tccccgccgc cgctttgtat ttcgccagat taatcgctgg tttcgccata aacgaatcat
    62161 cctgcggcaa aacgcggtcg ggctgaattt ctggcagccg cagttcttta aggaacattt
    62221 cggcgcgatg gataaacgca tcgtcgctac agccaaattg acgagcgatg ttcagcgcct
    62281 gctggacgtt gtaatacgcc atatagctgg tgaaggcgtt attattgaca tgttcggtat
    62341 attcgtctgg cccaataaca tcatgaattt ccagacggtc gttaaccctc accgtgcggc
    62401 taatccagaa ctttgcagtt tccagaagta gcgccatgcc ttcatgagca atgaaacttt
    62461 catcccccgt ggtctgccag tattgaacaa ccgcccaggc gatatcggcg accagatgat
    62521 gttccgcctg cgccgaggcc actttttgcc gcagcccggt gcgaatgtta atggcggcaa
    62581 attccggcgt ctcttcttcg ccgctgcgcg cgctttccca cggaaatagc gcgccctgcc
    62641 agccgttgcg tcgcgctttc tcctgcgcgc ctggcaagtt gtgccagcga taacgcagta
    62701 aacttctggc aatcgtcggt tcgctaaaca gatggaacgg cagtaaaaat acttccgtat
    62761 cccagaaaac gtggcctttg tagccttccc cggtcaaacc ttttgccgca atactgctgc
    62821 gctcgtcgtg agcaggcgtc atgatgcgta ggtgataaag cgcataatct aacgcttgct
    62881 gatcgtgcgc atcgccaccg tttaccgtga tacgacgttt ctgccaccat tgacgccagt
    62941 tttctgtgga tgctgcaaga agttggtcgt aactctgctg tacacacatt tcaagctgac
    63001 gaagcgatgc actaccccac tcgtctaaag cgacgtgtct gtcgtcccgc cagtcgatcc
    63061 acacccgttt ttgcagcgtc agcgttttgc ccgcaggtag ttgtgcactg gtatgttgca
    63121 gcaagcggcg ctctttggcg gtatagcatt gctgcacgtc accgctcacc tggcagcaac
    63181 agctgatggc cacatcactg cgtccatcct gagtggtata gatcccctgc atcaaatgct
    63241 gaccaaacac ccgcacctgg gtttcgtcga gatgttgtcg tccgtggttg gtttgcgtgg
    63301 cgtcaatgcc tgttgaaatc agcactgacg cgtcagcgtc cagcggcgta atgctgattt
    63361 ccagcgccat cagcggcagt tgttctgccg aaacaaagcg acggctggca atggcataac
    63421 gtgcgccgct ggctgaagac cagacgacat tgcgacgtaa ttcaccactg gcgaagtcaa
    63481 gctcgcgctg ccacgtttcg cgggatagcg caaaaagttc accattcaag gtaatctcca
    63541 tccctatgac gtcaggcagg ttcaccagtt cgttgatgtc atttttcccc gcgcgatgat
    63601 aaagccccgc cagatacata ccgcgtgtct ggcgcgtata atcttcttca tggctggcgc
    63661 gaagcccaag atagccgttc ccctgcgcca tcagcgaagc atacttgttc agggtatgct
    63721 ggctgaaatg gggttccgtt aacgttactg gcctggtcat aattccacac gcgttcctgt
    63781 ttctgcggat tgatacaacg ccgccaccag ttgctggatg atgtacccct gctcggcgtc
    63841 ggctatcatc acgggcttac cttgtacgtg gttgataaag gcttccatac tgcgcagatg
    63901 acggttgtcg tctgccattt cccgttgcat cagcgtcatt aactcaccgt tgttatcggt
    63961 gtagatatgt gctggaaaca gcgtcgcccc ggctttatca ccacaaaagc tgacgttcat
    64021 aatcgactgt tcgcggatgt tgagtgcaaa tgaggtctca agccacagaa tgccgccgtt
    64081 atgaaattca atggtgccaa acagcgaatc ttcgacgctg taggttgccg ggtcccactc
    64141 gccaaattga ccgcagctct tttgcgttcc gatcttttga aagctatgcg cggtcacgct
    64201 tttcaccgcc ggaaagccca gtacatacat cgccgcatcc agcatatgaa tgccgatgtc
    64261 aataagcggc ccgccgccct gcaattcttt attagtaaag acaccccagc cgggaacacc
    64321 gcagcgacgc agggcgcggg cggtggtaac gtaaatctct cccaaaacgc cgttggtcac
    64381 ctgttcacgc agctgttgcg tatcgagtgc aaaacgatgg tgaaagtcgt aggccagcac
    64441 cttgccctgt ttgcgcgcgg tatcgcacat ttcccgcgct tgttctggcg tcatggcggg
    64501 cggtttttcg cacatcacat ggcagcccgc ttccagcgcc atcagggtat gttcgtaatg
    64561 aaaacggtta ggtgagcaga cgctaaccac atcaggtttc accgccagca gcatggcctg
    64621 cggatcgtcc cacacggatg cattcccgta tttttctgcc agcgcctgcg cctgggaaag
    64681 gcggctgtca cagacagcca ccagttccag atcgttgcgg gtgcagtagt acgaagcatg
    64741 aactttatcc gccacctggc ccgcgcctat gatcgcgact cgcagcggag agcttgtcat
    64801 tgcacttttc acaaagacct cttagcaggt acgcacccag gccaaagaat cacggtacgc
    64861 ctgggcagga tcttctgccc ggatacgccc ttcatacacc acataaccct gatagttatc
    64921 ggcgcgcagc tgttcaaaca gcgcgtggaa atcgagggtg ccgctgcccg gctggtaacg
    64981 atggttatcg gcaatatgca catgaccgag caagtcgcgg ttgtcgtgca acgcctgcgc
    65041 caggttatct tcttcgatat tcatgtgata gaaatcgccg ataatctgta catgtttaag
    65101 atcgttttcg acgatgtaac ggcgggcatc ggcgagggtg ttgatcatgt gatcctgata
    65161 acggtttaac ggttcgagat acaccacggt tccggtacgc gctgccacct gctccagtac
    65221 gcgcagggaa tcactcacca ttttgcggtc gccatccagg ctgcgcggcg aggtcatcgg
    65281 cggtaaacgg aaggtaaaca tgccccatgc agcaggaacg acgatacctt taccgcccac
    65341 ttcggccagc gcttcaagaa tgcgttcgat ctgctttaag ccattaagac gacgctcttc
    65401 gataaagtcg ccaatccagc cgtcatagcc gccgcaggcg gtggtcaccg gtaagccggt
    65461 ttctttgatt gccgctttga cttcttcgat gttgttgacc agcagtttgc cgtcaatctc
    65521 aaaaccatcg aagcccatct ctttgatata acgaaatttc tccagaatat tttccggaaa
    65581 gaatgcctga ttctgtgtgc ctattttcat tttttcattc ctttgaatta aaacgtaacg
    65641 cccattttga tgctctgttc cggatgctga tcgacatact gcatgtagct ttccgggcta
    65701 ttggcaaagg tcaccaccgg gtcgatcaaa tcttcacaat tgagataacc gttcatcagc
    65761 aattcccagc aggtttcttc aatacgcttg cgactccagc gcggataatc cgggttcggt
    65821 tcactgcacg cacgagagaa gacaattttg gcgttgttga aatgggcttc acgtccgagg
    65881 ttgaaacctt cggcaaatgg tttggcaaat gcgacatacg agatggtgcc gccatatgcc
    65941 aggccgcgaa gtgccgattg cagcgcgtcg gcgtagccgc tggtttcgat aatcacatcg
    66001 gcaccctgct tgccggtcag cgttttgatc tctttaccta cgtcagcgcc aatggggtta
    66061 agacagaaat ccgcaccgtg gcgacgggca atctcacaac gacgggtaat aggatcgacg
    66121 ccaattacca ccgacgcgcc agcgcgtttt gccagttgga tggcaatttg accgatcgcg
    66181 ccaagcccta ccaccacgac aaaatcccct acgcgtacgt tggcatcgcg cacgccgctc
    66241 atggcaaact gcgccgggtc gtaacagacg gcgtttttcc aggagctgcc ttgcggcatt
    66301 ttgcgcagct tgtagttatt cactgcgtta atgatgaccg tctcggagag cgggccgtag
    66361 ccgcatacgc tgtcgcccac cgcgtagtcg gtaacgtcgc tgccgcactc gataatgtcg
    66421 ccaaccacca tgttgccaag ctggaatttg ccaaactcaa tgccgcgcgg cgcatctgcg
    66481 ggacgcgggg tgaacatctg ccactcgccg ttaaagtctt catcgataaa cgggctggcg
    66541 gcgcggaagt cgaccacttc cgttccgtgt ttcggtgcgc cgaaacgcac gcggatcttc
    66601 acttcattgg ctaaaatcgc ccgatcttca tactcaacca gcgcggcaac gcgcggtgct
    66661 gtggctacta actttttcat gtaaaactcc ttgtcaagaa actggccgct ttagcccttc
    66721 acgccaccgg cggtcaaacc actcttaata aaacgctccg aaagcgcata cataatcacc
    66781 accggcaatg cggtcaccag cgaggccgcc atcatccgtc cccagatgta atcaggcgta
    66841 ctgaacagcg cgttcaggcc gactggtaag gtgaaattgc tggcgctgga gaggaaaatc
    66901 gacgcaaaca gatagtcgtt ccatgccacc ataaagcagt agacgaatac ggatatcagc
    66961 ccggacatcg ccagcggtac cgtgatgcgg aagatgattt gcagccggtt gaggccatcc
    67021 atcatcgccg cttcttcgat ttcatcgggg atggtgtcga agtagctttt cagcataaac
    67081 acggcggtag gcagggtttg cgtaaccatg gtgatgatca gcgccatctc ggtgtcgtaa
    67141 acgccaagcg cggtgatgat tttgaacagc ggcaccacca gcaaaatgcc ggagaacatg
    67201 tacaccgtgt agaagctggc gttgatggtc attcgccctt taaagcgcag gcgggaaagc
    67261 gcgtaagccc cgagaatgcc gagaaatact gctatcacgg atgaaactac cgacaccacc
    67321 atgctgttac ggaaataatc gacaaacggg aaaatcatcg ggttaaaaat gtcgacataa
    67381 tgctccagcg tccactgctg cggcagcagc gtaggatgca gcgagatcgc ctcttttgcg
    67441 ctcttgaacg aggtcatcag catcacaaaa aacggaaaca gcgtgatgat gagaaacagc
    67501 gccagcccgc agtaaaaacc gatgcgactg agtgtgcgtt tatttgttgc cattgaggtt
    67561 cacccgtttc ctggtcagca gaatgacagc gaaaataatg atgaagagca ccaccgagat
    67621 cgccgccgct ttccctaagt cattaaaggc aaaggcggtt ttgtagagat agacaccgag
    67681 aatatcgacc ttggtcgtca gcagataaac atccgcgaac atgtagaaca tccagatggt
    67741 gcgcagggtc accaccgtcg ccaggaccgg cataatcgcg ggcagcgtga cgatacgaaa
    67801 ccgttgccag gcattagcgc catccatctc tgccgcttcg tacagcgatt tgtcgatggt
    67861 ctgcaaaatc gccagaaacg aaataaaggc ataggggaag tagcgccaga tggcgaacag
    67921 caccaccagc acaaagctac tgcccggatt atcgaaccac agcggtgcct gctcatagag
    67981 atgcagaaga tcgacgccga ggtagttcac aatgccgtaa ccgttgttga acatgtattt
    68041 ccaggcgaac accagcgaaa tagacggcgt tacgtaggag aggatcacca gcgaacgcgc
    68101 ggttttgcgc aggcggaact cgcggttgaa aaacatcgcc acggccagcc cgagcacggt
    68161 gctgcccgcc accaccagcg cggtatacca gaccgtcatc cacagcgagt gccagaagcc
    68221 gggatcggag agaatacgca catagttact caccccaaca aaggttgact cgatgttggg
    68281 attgagcggc agacgtaaaa aactgatttc gatattcgac accatcggcc acgccaccag
    68341 accgcccagc agtaataagc tgggcgcgag aagcagcagt gcaaaaggca tatcggaacg
    68401 acctgaaaaa agcctgttca ttgcggattc ctgtcctggg tttagtgctg ttcgatcagt
    68461 tcatccagct ttttctggct cgcttgcagc gtgccaggga gatcggcttt ccccacggtg
    68521 acgttatgca ccattgaact caccacgcca gaccccgtca catcgcccat gcgggtaaag
    68581 tttttatccc ctactgcgcc aaagacctga atatttggca gttcgctaat caactgattc
    68641 ggcaagtctc ccagcgcctt aatcacgtcg ttatctttcc aggtggcagt cgtcacaacc
    68701 gctttgttca ccggcagcgc cgcgcctggc gacatcatca cccagtcggc aatgttgtcc
    68761 gcctgctcca taaaggtgac aaatttttcc gccgcctccg tctcttcgct cttttgcccg
    68821 gcggtaatgg ttagcgaggt caacatgccg tagaccgccg agtttttctc ggttggcacc
    68881 acgaaaccga catttttcgg gtcgccttct ttaatcacag ccggaaggat ataggtggag
    68941 taaatcgcca tcggcgcggt gccgttcata aaggcgtctt tcacttccat aatgtcgtta
    69001 gaacccggca tggtgttggc agcaaggtcg cggtaatagg tcagcgcctg catcatctct
    69061 ggggtatcaa gggtgatttt gccttcggcg ttaaagacgt tagcctgatt ggataacgca
    69121 aactgggaga aagattgctc cgtcagcacg ctttctgccg tcggcagtgc aataccgtat
    69181 tttttattcg ccggatcgtt cagtttctgt gcgacatcca gcaactgttg ccagtttttc
    69241 ggctcatcca gcccggcttt tgccagcaca tctttgcgat accagatgcc gccaatccag
    69301 gcgctgacag gaacaccggt ccatgcgcta ccatcttcgg tgcgcacaat ccgcagaacg
    69361 ccatcgtaga acgcgccttc accgacgttg ctgatgaccg tggcaaccgc caggcgatcg
    69421 ataagctgct ctttgtccat aactttggcg tagtcatggc tggtttcgat cacttccggc
    69481 agcgaaccac tacgtgaaag ggtaatgact ttggtgttat aggcgtcttc ttccacgggc
    69541 acttgtttaa cggtgatgcc cgggttttct ttttcaaaac gcgcaattaa ctgactaatt
    69601 accgcctggc gttcctgttc caccgaagaa tgcataaact caatggagac attcgtttta
    69661 ttttcttctt tacaacctga aatcagggcg caggaaacca gtgctgataa cagcacgatt
    69721 tttgatttaa tcatgagatg ttccttttta tttaatccac ataacctgcc aggggcgcag
    69781 cgttatttca ttacccacta tatcaacttc actaatcaga tcccgaccgt gcaggccagt
    69841 aatatttata tgctgaatat tttcactgac attaaacaat cctgtcagac aattaccatc
    69901 cgcgttgctt ctttgaatac acattacgga tgaattaacc gtgtcgatgg taaaatcatt
    69961 atctggatga aactcgttat gacttcgacg aattttaatt agtcgcgaca attcatgata
    70021 taccgcgtgc cttaacgtcg ttttattgtt cagttcggtc gtgatctctt cactgtaata
    70081 ttttttacgg ttaatcgcac ggttatattc cagtttttcg acacctgcgt aatcattacg
    70141 cgagcccaga atactttgaa tatatatcgc tggcacaccg gggaaactta acaaaatcgc
    70201 atgggcaagg ataaacctgg cgcaacgttc ttcatcgcta ctctcgcggc ggtttaacgc
    70261 atccatataa gtgacattca tttcatacgg gctacgcgta ccgtcgggat tatttttcca
    70321 gttaactaat gccccttcct gctgtaatgc ctcgaccagc gctaatattt cgctttcggg
    70381 tagcaagcca cgcagtgggt taagcccgat gccatcgtga gaggcgagga agttaaacca
    70441 ggtggtgttg ctggaaggta gtgtcaggtt ttgcgcccac gcacaaagcg cctcaacgtt
    70501 ctgtttttgc accgcatgca gcaccagcgg cggcagcgag aactggtaca ccatatgcgc
    70561 ttcgtcatca ccgttgccaa agtaagcaat gttgtctctg tgcggaacat tggtctcggt
    70621 aatgatcact gtacctggtg ctacgtcatc aataatcgac cgtaacagtt tgataatcag
    70681 atgtgttttt tccagatgga tgcagcttgt tcccggctct ttccacataa agccaacggc
    70741 atccagacgg acatattctg cgcccttttc caggtagcac agcaatacat ccaccatcgc
    70801 cagtaacact tcagggctac ggtaattcag gtcaatttga tcgtcactaa aggtggtcca
    70861 taaatggcgc gttgaatgat cgcgcatctg gaatggcgtt aataacggta acgcacgcgg
    70921 gcgagtgacg acgctgagat cggtttgcgg gtcaacggca ataaaaaaat cttcaaaacc
    70981 tggctgctgt tgtaaatagt ttttaaacca ttcacttttt gccgacatat ggttgcagac
    71041 aaaatcaaac attaaatgac tgcattcacc gagttgctga atatcctgcc actcccccgc
    71101 ttcactagcg acctgttgat aatcaattac cgaaaagcca tcatcagatg accatggata
    71161 aaaaggtaat aaatgaacat gtgaaaaaat gctttgcagc cattgagggt aaaactgatt
    71221 aaatgtgggt agtggtttta aatcattact gtgaaattga tcggcatagg tgattaacac
    71281 gacatcactt tcatcccagt gttttttacg tcgcagtgta attaatcgtt tcgcactctc
    71341 aagacgcgtt acaagtttct gtaaatgagt tgtggtaaat gttccaccgt agatttcgtc
    71401 caggtaatcc gtaattttct gtttcatgtt gcctttccgt ggtagcggtc ccatgaagcg
    71461 agagactact ccgcagaaaa taaactgtca attgagcaca agggttttag tcacgcagga
    71521 aatcattttt taccagggaa aaagcgtatt tgtgagctga cgcaaataat ctatggggat
    71581 gtaaataagg tgtgacagaa aaagtaaacg gcgcataagc gccgcttagg gtggattctt
    71641 ttaacctttg accttcggca ttgcgatgtc tttcaggccg ccggcgttct caacgtgggt
    71701 atatcccatc tcgctaagga tgtcttttgc ctgccctgac tggcgtccgg cattgcaata
    71761 cactttcacg gtgtcgtttt tatccggaac ggcggtggca atgcgctctt tcacttcctt
    71821 caggggaata ttgatggccc cctgaacgtg ctcttgctga tactgctcag gaacacgaac
    71881 atcgatccag tgttcagcgg cgaaaacggg cagtgaaaac accagtgcca gagcaagtaa
    71941 gcctttttta aacatgtaag cgtccttcta tggatgaaaa ttgccatcca taatacgcct
    72001 tagctttaac aatttttgcg aaactcccct caccttttat aacgctgcgc cagtttattg
    72061 gcagcccgac ttaacagcgg ttccagcgcc acagccagca acattttcag cggtcggcga
    72121 gcaactgatt ttatcgccca gcccgccaca cccgccgggc catagcgcag tgcggtaaga
    72181 agtaccagct tgcctgctaa tttgaaacca ggcttcacct tttgcccggc ctgttgccag
    72241 cgagtattca taactttcct cacagttgac ggaaacggct acgtaacgtg aaagtatcgg
    72301 aagtgacata acgttccatc tcgcgtaaac gcgtttcact tgccgccagt tcacggtcga
    72361 cttcatccag caattcactg ctggaaggta gctgctcacc aaaggccatg ttgtccggca
    72421 ttggatcaag cgcaaatgac aaaatgatgt aagcaaccag ggtaaacagc gccagaccga
    72481 agaaaatcga cagcaccacc aggatacgca ccagttttac tggtacatca aaatagttgg
    72541 caatcccggc gcagacgcca cggaccatgc cctgctgtgg aatacgccat aattttttat
    72601 tgagattaat gcccgccatt agcgatccct ccagttcgga tgttctgcat caagaatgga
    72661 ttccagcgcc tgaatacgtt cgcgcatccg ttttgcttca tcagccagtt gcgctaatcg
    72721 ctgctgctca ctttgcgaca attcactgcg accagaacga ttgctgtaat gcagccataa
    72781 ccagatcggt aaaacaaaca gcacaaaaat ggttaacgga atagccagaa atagcgcgct
    72841 cataaggact ccttagacga tgagcggcgg cgcgttcgga cgccgcctgg atgttattat
    72901 tgattgtctt gcttcatttt ggcttttaat tgtgccagtt gctcgctgat tgcatcatcg
    72961 gctttcagtt cggcaaactg atcgtccagc gatttttgtt taccgaagct gtggctttct
    73021 gcttccgctt ccatctggtc aattcgacgt tcgaaagatt cgaaacgagc cattgcttca
    73081 tccagtttgc cactgtccag ctgacgacgc acatcgcgcg acgagtttgc cgcctgatgg
    73141 cgtaacatca atgcctgctg gcgagcgcgt gtttcgctca atttgttttc cagctcgccg
    73201 atctctttct tcatacgcac cagcgtatcg tccaccagcg tcacttcatg ttccaggctc
    73261 ttaatcagat cggtcagttt ctgtttttca attaacgccg cacgcgccag atcctctctc
    73321 tctttcagca gtgccagttc cgctttttcc tgccattcaa tttcacgagc cgacgcttgt
    73381 tcaatacggc gagtcagctg tttcttttct gccagcgcac gcgccgaagt agaacgtact
    73441 tcaaccaatg tatcttccat ctcctggatc atcagacgca ccagtttctg tggatcttcc
    73501 gctttctcta acagagcgtt gatgttggca ttcacgatgt cggcaaagcg agaaaaaata
    73561 cccataatgt tgtcctcttg atttctgcgt tcaggattgt cctgctgaac tgttaataca
    73621 atttgcgtgc caatttttta tctttttgat ttataaagat ctgattgaag aatcaacagc
    73681 aacatgccag gatgaattag cgaattacac taacaagtgg cgaatttcat catggcagaa
    73741 tacaaagata atttactcgg tgaggcgaac agctttctcg aagtgctgga acaggtttcg
    73801 catctcgcac cgctggacaa accggtgctc atcatcggcg agcgcggcac aggtaaagag
    73861 ctgattgcca gccgtctgca ttatctctcc tcccgttggc aagggccgtt tatttccctt
    73921 aactgcgcgg cgttaaatga aaatctgctg gattccgaac tgtttggtca cgaagcgggg
    73981 gcgtttaccg gtgcgcaaaa acgtcatcct gggagatttg aacgtgccga tggcggtacg
    74041 ctatttcttg atgaactcgc tacggcaccg atgatggtgc aggaaaaatt attgcgtgtg
    74101 attgagtacg gtgaactgga gcgcgttggc ggtagccagc cattgcaggt gaatgtgcgg
    74161 ttggtatgcg cgacgaatgc cgatctcccg gcgatggtca atgaaggtac ttttcgcgct
    74221 gacctgctcg accggctggc tttcgatgta gtgcaactgc cgcccctgcg cgagcgcgaa
    74281 agcgacatta tgctgatggc agaacacttt gccattcaga tgtgtcggga aatcaagctg
    74341 cctctgttcc cgggttttac ggagcgcgcc agagaaacat tgctgaatta tcgctggccg
    74401 ggaaatattc gtgaattgaa aaacgtggtg gaacgttcag tgtatcgcca cggcaccagc
    74461 gattatccgc ttgatgacat cattattgat ccctttaaac ggcgtccgcc tgaagacgct
    74521 atcgccgttt cagaaatcac ctcgcttcca acactgccgc tggatttacg tgagtttcag
    74581 atgcagcagg aaaaagagtt gctgcaactc agtttgcaac aagggaaata taaccagaag
    74641 cgcgcagctg aattgctggg gttaacctat catcagttcc gcgcgttgtt gaaaaagcac
    74701 cagatttagc gaagttgggc aatacaactt gccggatgcg gcgtgaatgc tttatccggc
    74761 atacataatc aatacgtcgt ttgcaggcct gataagcgca gcgcattaga cattattgcg
    74821 ttgggctatt aatctttcag cgcatcctgc aaaattttca ttgccgcatc gaattgcgca
    74881 tccgggatgg tcagcggata caggaaacga atcacgttgc cgtatgcgcc acaggtcagc
    74941 aggagcagcc cctgcgccag cgcgcgttgc tggattttct gtgcaatcgc cgctgacggc
    75001 tcgcccgttt gcggatcgtt aaactctgcc gcaatcatag accccagacc gcgtaccgcc
    75061 gcgatggccg gaacgctttc tttggcatca atcaacgtgt ttgtcaggcg ctggcccagt
    75121 tgattcgcgc gttcacagag tgattctttg tcgataatgt tgagcacagc gtgcgcggca
    75181 gccaccgcca gcgggttccc ggcgtaagta ccacccaacc cgcccggcgc gggcgcgtcc
    75241 ataatattcg cgttaccgac cacgcccgaa agcggcatgc cgcccgcgag gcttttcgcc
    75301 atcgtcatta agtccggctt atcggcgtag tgatccatgg caaacagttt accggtacgc
    75361 gcaaagccgc tttgcacttc atcggcaatc atcacaatgc cgtgctcgtc gcacaggcgg
    75421 cgaatggcgg caaccagctc ttttggtgca acgttgaaac cgccttcgcc ctgcaccggt
    75481 tcgaaaataa tcgccgccac ctgcttcgct tcaatgtccg atttaaacaa gcgttcgatg
    75541 gcgtcgagag agtcctgcgt tgaaacgcca tgtaaatctg tcggataagg tacgtgatat
    75601 accgaaccgg ggaacgggcc gaagccgatt ttgtacggcg cgacctttcc ggtcagcgcc
    75661 atggtcatat atgtacgacc gtggaagccg ccgctaaacg caatcacgcc agggcgtccg
    75721 gtatgggcgc gggcgatttt caccgcgttc tccaccgctt ccgcaccggt ggtgaagaac
    75781 gcagttttag cctgcccgct caccggggca agggcgttga ttttctccgc cagggtgacg
    75841 tagctttcgt acggcacaat ctgatacgcc gtgtgggtaa actgttgcaa ttgctgctcc
    75901 accgccgcga ccagatcagg gtggcgatgc ccgatattca gcaccgcaat gcctgcggcg
    75961 aaatcgatgt attcgttgcc ctctacgtcc ttcagcatgg cgttttctgc cgactgggcg
    76021 aagaagttac acatcacgcc aaccccgcga ggggtagcag aaagacgacg ctgatggaat
    76081 tcattgttgc tcatgtttca caccttttga ctcttcactg ttaatcggaa attaaacgcc
    76141 cagacgatcg cgcaggctgt aataagccgc gcccatcgcg gtaaacggaa cgcgcagcgt
    76201 gcgcccgccg gggaacgggt aatgcggcag attggcgaag gcgtcgaagc gttcggcgtc
    76261 accgcgcagc agttcagcaa tcaaacgccc ggcaagatgg gtacaggtga cgccgtggcc
    76321 gctgtagccc tgcatgtagt agatgttggt atcgaggcga ccaaactgcg gcatgcgtga
    76381 cagggtcagc aggaagttgc ccgtccagcg gtaatcaatt ttcacgccct tcagctgcgg
    76441 gaaggttttc agcagtttcg gcaccacaag gcgctcaacg tcatccgggt cgcgcgcgcc
    76501 gtagaccacg ccgccgccgt acagcaggcg gttatcggcg gtaagacggt agtaatcaag
    76561 cagatagtta cagtcttcca cacagtagtt tttcggaatc agcgaacggg ctaaatcttc
    76621 cgacagccgt tcagtggtga tcacctgcgt gccgcacggc atgctgcgtt tcgctagttc
    76681 cggctctact ttatcgccca gatacgcatt cccggcgaca atcacatact tcgccgtcac
    76741 ctgaccattg gcagtccgca ccacggctgg cgtggtgtgc tggatctgcg tcacggcgga
    76801 aagctcatac acgcgccctc cgttcaggcg gatggcatcg gcttcaccaa tggcgaggtt
    76861 tagcgggtga atatgcccac cgctgtgatc cagcagcgca ccagtgtagc gatcgctggc
    76921 tacttcacgg cgaatggcgt tggcatccag cagctccagc tgtttattgc cgtagcgttc
    76981 ccagttctct ttctgctctt cgagtgtggc gagctgttta tcattcatcg ccacaaacag
    77041 gccgccgggg cggtagtcgc agtcaatctg ataacgtttg atacgttcgc ggatgatctc
    77101 tccgccttca aacatcatgc tgccgagcat acgggcggtg tccatgccgt agcttttttc
    77161 gatcacgtcg atgtcgcggc tgtaggagtt cacaagctgc ccgccattgc gtccgcttgc
    77221 gccgaagccg atgcgtgagg cttcgagaac cactacatca aagcccgctt ccgccagatg
    77281 cagcgcggag gaaagcccgg tatagccgcc accgaccacg caaacgtcgc aggaaatcga
    77341 ctcattcagc gtgtcgaatg gcgcgtattt attcgcactg gcggcgtagt aactgctggt
    77401 atgttcggtc atttcaggcc tccaggctta tccagatggt tttcagttcg gtgaattttt
    77461 caagggcatg cagggatttg tcgcgcccgt tgccgctctg cttatagccg ccaaacggca
    77521 cggtcatatc gccgtcgttg tagttattga cgaagacgga gccggctttc aggcggcgac
    77581 tcatgcggtg cgcgcgggag aggtcgcgcg tccataccgc cgcgccaagt ccgtactggc
    77641 tgtcgttggc aagctgtagc gcctgttctt ctgatgtgaa acgcgtgacc accagcaccg
    77701 gaccgaaaat ctcttcgcgg cttaaggacg cattcgggtc tacctccaca aagatggtcg
    77761 ggccgatggc ggcagccagc tcggcgttac ggccatccag cagcagttgc cctttgcttt
    77821 cgccttcccg aataaagcta tggaccgagt cggcgtgggc gcagtcgatt aaggtgccca
    77881 tggtggttgc gggatcaagt ggatggcccg gctgccagtt ttgcgcctgc tgttttaaca
    77941 gggctaagaa ttcatcggca atgctctctt ccagcaacaa acgcgttccg gcgatgcaca
    78001 cctggccctg gttgtagaaa atgcctgcgg cggtggcgct tgccgcctgt tgcaaattcg
    78061 ggcagtcggc gaaaacgatg ttggcgcttt tgccgcccgc ctccagccag acgcgtttca
    78121 tgttgctgtc gcccgcgtcc ttcagcagct gtttcccggt gcgggttgag ccagtaaagg
    78181 caatggcatc gatatcgtta tggcgcgaaa gcgcctgccc ggcttcatga ccaaaacccg
    78241 tcaccacgtt caacacacca tccggcagcc ccgcttcttt cgccagcccc gcgagacgaa
    78301 tcgcactgag cggtgatttt tcagacggtt ttagaatcac gctgtttccc gccgccagcg
    78361 ccgggccgag tttccagcaa gtcagcagca gcgggaagtt ccacggcacg atggcggcaa
    78421 tcacgccgac cggttcacgc acgatcatcg ccagctcatg gctactggtg gtcgccactt
    78481 cgccatacac tttgtcgatc gcttcggcgt accagcgaat ggcgcgcgcc gcgccgggaa
    78541 tatcatcacg caggctgtga cgaatcggtt tgccggtgtc gagcgtttcc agcagtgcca
    78601 gctcttcggc gttggcttcc attaaatcgg cgagtttatt cagtaccgct ttacgtttag
    78661 ccggagaaga gagtgaccag tcgccgcgtt caaatacgcc gcgtgctgcg ctcaccgcac
    78721 ggtcgatatc gacgctcttg ccgcgggcaa ttttcgccag cggtgcctgg gtgaccggat
    78781 caacggtttc aaaagtttca ttttcctccg cagcagtata ttcaccgtta ataaataagc
    78841 gggtttcaat ggcgagactt aacgctttat cctgccagta agccagatga taaaaattca
    78901 ttatgactcc tgtttcacgt ctatcagata tatgcagttt gtgaacgtca gggcgcagag
    78961 atccccgggc cgtatgcccg tttatttctg gcgacattct ttatggattg ccgggcgcat
    79021 tgcgcttacc cggcttacag aacaaaaaga ttaaaacgtg gtgggcgtat gggcgctgat
    79081 aattcggcaa atacctgccg acgtattact gaaactgtgc gggatgccgg tattaatggc
    79141 ataactttgc cccgcgacga gatgataatc ctgaccatta atggtcagaa caatttcacc
    79201 ttccagtaca gtgcctattt cctcaccctg atgcttaatt ctttccccag tggttgtgcc
    79261 cggctggtaa gtttcaaaga tcatcgccag cgtgcgattc gggttaccgt tatgaaccag
    79321 cttcattgac acaccctgac tgcccatctc aattaagtcg tcctgattaa tgacgacctg
    79381 cggctcatca ggtttttccg gctcggaaaa gaattccgag agtgacagac catacacctt
    79441 cagcagcttt tgcagcgtac tgatggcagg gctgacttta tcttgttcta tcgtactgat
    79501 agcactgtga gtcagcccgg agagttcggc ggcacgacgt tgtgaaagcc cctgctgctg
    79561 gcggatttcc gacaagcgtt ttcctggcgc cagtccctca tcactcatat ttgcatttcc
    79621 ttaaactgta gtggtcagag tcgctttttt tcagcgatat ggtgctgaca agcggtgata
    79681 aagccctcga acaatatacg cgaaagcgcg tactcgctac tgttccattc cgggtgccac
    79741 tgtacgccca gcgcaaaagg atgattgatg acgctaaccg cctcaactaa gccatccggc
    79801 gagcgagctt caacacgcaa ccgtgggcta acgaccttcg ccccttgtcc atgcagagag
    79861 tttacccaaa agttgctaca ttcaggtaac aacgcagaca gtaatccccc ctcttcaacc
    79921 agaacttcat gcgacggcgc atattgctgc tccaccggca gttcgggatc ttcccgatgt
    79981 tccagcaatt caggctgttc gcacagcttg cgatgcaacg aaccaccggt tgccaccacc
    80041 agttcctgta aaccccggca gatggcgaaa atggggatgc gcctttcgag tgcggcatta
    80101 attaacgcca tgctcagaag atcacgcccg ggatcggcgt caggctcatc gccgttttca
    80161 ccatataggt gcggctgcac attgctggga ctaccaggaa gataaatacc atcgagtttc
    80221 ggcaaaagtt gttcaagtaa tgacggttcc gccagcgcat gtggcagcgc aattggcaag
    80281 ccgcctgcgt ggatgatggc attcaggtac ttttcttgca gagtctgggt cgcatgaccc
    80341 ttaagcctgt tcctgcacat tacgacaccg ataaccggat tgttcattat attttccatg
    80401 ctcaatctca caaagtggac taaattatcg ccattactgc gctttaaatg acctttatgt
    80461 tcaatatttt ttcaatctag cagcgggttt tcatttttgc aaactcaatt taacatttga
    80521 caaacattta gtttgcatac agattcgaat agtggtcatt atattttacg ctttgataac
    80581 gagcggaaaa caaaccaaag gcgaagaatc atggaaacca atatcgttga agtagagaac
    80641 tttgttcagc agtcagaaga gaggcggggt agcgccttta cgcaggaagt gaaacgctac
    80701 ctggagcgct acccgaatac gcaatatgtt gatgttttac ttaccgattt gaatggttgc
    80761 ttccgtggaa aacgtattcc tgtttcaagc ctgaagaagc tcgagaaagg gtgttatttc
    80821 ccggcctcgg tgtttgcaat ggatattctg ggcaacgtag tagaagaagc gggcctgggt
    80881 caggaaatgg gcgagccgga tcgtacctgt gttcctgttc tcggttcctt aaccccttct
    80941 gccgccgatc cagagtttat cggtcagatg ctcctgacca tggtcgatga agatggcgct
    81001 ccctttgacg ttgagccgcg gaacgttctt aaccgcctgt ggcagcagct gcgccagcgc
    81061 ggattgttcc cggtcgtagc ggtagagctg gagttctatt tactggatcg ccagcgcgac
    81121 gctgaagggt atctgcaacc gccctgcgcg cccggcaccg atgaccgcaa tacacaaagc
    81181 caggtttact ccgttgataa tctcaaccac ttcgccgacg tgctcaatga tattgatgaa
    81241 ctggcgcagt tacagctgat tccggctgat ggcgcggtcg ctgaggcctc gccgggtcag
    81301 tttgaaatca atctttacca taccgataac gtgctggaag cttgcgatga tgcgctggca
    81361 ctaaaacgcc tggtgcgtct gatggcagaa aagcataaga tgcacgccac ttttatggcg
    81421 aagccgtatg aagagcacgc gggcagcggg atgcatatcc atatcagtat gcaaaataac
    81481 cgtggcgaga acgtgctttc tgacgcggaa ggcgaagatt cgccgctgct gaaaaagatg
    81541 cttgccggga tgattgacct gatgccgtca tcaatggcgt tgctggcacc aaacgtgaac
    81601 tcgtatcgcc gcttccagcc aggtatgtat gtaccgacgc aggcgtcgtg gggccataac
    81661 aaccgcaccg tcgccctgcg tattccctgc ggcgatcgcc ataatcaccg cgtggaatat
    81721 cgcgtggcgg gtgccgatgc caacccgtat ctggtgatgg cggcgatttt tgccggtatt
    81781 ttgcatggcc ttgataacga actgccatta caggaagaag tcgaaggtaa cgggctggaa
    81841 caggaaggct tacccttccc gattcgccag agcgatgccc tgggtgagtt tatcgagaat
    81901 gatcacctgc gccgctattt aggcgaacgc ttctgccatg tctatcacgc ctgtaaaaat
    81961 gatgagctgt tgcagtttga gcgcctcatc acagaaacag aaattgagtg gatgttgaaa
    82021 aacgcgtaat accccttgcg gggttgtttc atcggcctga gcggagccag gcctgacatt
    82081 tgctggtaat ccagacattt cccggatgtc gcgttatgga gcgcaggcgg caacgggctt
    82141 ccgttaacga ttaagactgt gacgaggaaa tgagatgatg ccgatgatta aatccccgca
    82201 tggcgaggga ggctgcgtat gcgcccctcc tgcgactgac tggactccgc cccctttgct
    82261 tcccttgcta aacaggtttg atttcaggtc gacacgaccg caaaccttat tacgcagggg
    82321 aggcagcaac tatggctatt aattcaccac tgactattgc tgcgcaatct ggcaaaaccc
    82381 gtctgcgaaa atcactgaaa ttgtggcagg tggtgatgat gggtctggcc tatctcacgc
    82441 cgatgaccgt atttgatact tttggtattg tctccggcat tagcgacggt cacgttccgg
    82501 cgtcctattt gctggcgctg gcgggcgtgc tgtttaccgc tatcagctac ggcaaactgg
    82561 ttcgccagtt tccggaagcc ggttcggcct atacctacgc gcaaaagtcg attaacccgc
    82621 acgtcggatt tatggtcggc tggtcatcgc tgctggatta tctctttttg ccgatgatca
    82681 acgtcttgtt ggcgaaaatc tatctctccg ccctcttccc ggaagtgccg ccgtgggtgt
    82741 gggtggtaac cttcgtcgcc attttaaccg ccgcgaatct gaagagcgtc aacctggttg
    82801 ctaacttcaa taccctgttt gtgttggtgc aaatctccat catggtggtg tttatcttcc
    82861 tggtggttca gggactgcat aaaggagaag gcgttggcac cgtctggtca cttcagccgt
    82921 ttatcagcga gaacgcgcac ctgatcccga ttattaccgg ggcgacgatt gtctgttttt
    82981 ccttcctcgg tttcgatgcg gtgaccacgc tttcggaaga gacgccggac gccgcacgcg
    83041 tgatcccgaa agccatcttc ctgacggcgg tctacggtgg cgttatcttt atcgctgcgt
    83101 cgttctttat gcagctgttc tttcctgata tcagccgctt taaagacccg gacgccgcac
    83161 tacctgagat tgcgctgtac gtcggcggca agctcttcca gtcgattttc ctctgtacca
    83221 cgtttgtgaa cacgttagcg tctggcctgg cgtcgcacgc cagcgtgtcg cgtctgctgt
    83281 atgtgatggg gcgtgacaat gtgtttccgg agcgcgtgtt tggctatgtg cacccaaaat
    83341 ggcggactcc ggcactgaac gtcattatgg tcgggattgt cgcgttgtcg gcgctgttct
    83401 tcgatttagt taccgccaca gcattgatta acttcggtgc tctggtggca tttaccttcg
    83461 taaatctgtc ggtgtttaat catttctggc ggcgtaaagg aatgaataaa agctggaagg
    83521 atcacttcca ctatttgctg atgccgctgg ttggcgcgct gacggtgggt gtgctgtggg
    83581 ttaacctcga gtcaacgtca ctgacactcg gtctggtatg ggcttcgtta ggcggcgcat
    83641 atttgtggta tctgatccgc cgctatcgca aagtgccgtt gtatgatggt gacagaacgc
    83701 cggtgagcga aacgtaatag tcggatgcgc ggcgcattat cctggctgag ggtaatgcac
    83761 cgcgccatta actataaaaa gatgtatgac ccggatcacg agtgctatca tccgccctta
    83821 tgcttagcgc attaacccca ggggcaaata atgaaccacg atatcccgct aaaatatttt
    83881 gatattgccg atgagtacgc gaccgaatgc gcagagcctg tcgcagacgc tgaacgcaca
    83941 ccgctggccc actacttcca gttactgctc acccgtttga tgaacaatga agagatcagt
    84001 gaagaagccc aacatgaaat ggctgctgaa gcggggatta atcccgtacg cattgatgag
    84061 atcgcagagt ttttgaatca atggggtaat gagtaattat ttcattgcag acgatgggtc
    84121 agtatcgttg tccggataaa gcgttcacgc cgcatccggc taacaatgac acgcactgca
    84181 gtgtgcctca atgggtttct cacgatcgta ccgctctgct cctcgctaag ttgttctgtg
    84241 agttatagtt atagagaaat cacgggtacg aatgttgaac agatggcgac gccacctgtt
    84301 caacgaccaa ccacacggcc ctcattacga cccctgaaca caaacggtaa tggcaaatgt
    84361 cattaaatat tagtaagata gcctctttac ataaaatcca ttaatattat gcgccaggta
    84421 ttatcgtctc ttttggtgat tgctggactt gtgagtggtc aggcaatcgc cgcgcctgaa
    84481 tcccccccgc atgctgatat ccgcgacagc ggttttgtct attgcgtcag cgggcaagtc
    84541 aacaccttta acccatccaa agcgagcagt gggttaattg tcgataccct tgccgcccag
    84601 ttttatgatc gactgctgga tgtcgatccc tatacctatc gcctgatgcc ggaacttgcc
    84661 gaaagctggg aagtactcga caacggcgcg acctatcgct tccacctgcg tcgcgatgtt
    84721 ccgtttcaaa aaaccgactg gtttactccc actcgtaaaa tgaatgccga cgatgtggtg
    84781 tttaccttcc agcgaatttt tgaccgcaac aacccgtggc ataacgttaa tggcagcaac
    84841 ttcccctatt tcgacagcct gcaatttgcc gataacgtga aaagcgtccg caaactggat
    84901 aatcataccg ttgagttccg tctggctcag ccggatgctt cttttttgtg gcacctcgcg
    84961 acccattatg cttcggtcat gtcggcagaa tatgcaggga agttagagaa agaagatcgc
    85021 caggagcaac tcgaccgtca accggtcggc actggaccgt atcagttgtc ggaataccgc
    85081 gccgggcaat ttattcgcct acaacgtcat gatgacttct ggcgcggcaa accgttaatg
    85141 ccgcaggtgg tggtggattt aggctccggc ggtaccggac gtctgtcgaa actcctgacc
    85201 ggggaatgcg acgttctggc ctggcctgcc gccagtcagc tatccatttt gcgtgacgac
    85261 ccgcgcttgc gtttaacgct gcgcccgggg atgaacgtcg cctatctggc gtttaacacc
    85321 gctaaaccgc cgctaaataa tccggcggtc cgccatgcac tggcactggc gattaataac
    85381 cagcgcctga tgcaatccat ctattatggt acggctgaaa cggcggcctc tattttaccg
    85441 cgcgcctcgt gggcctatga caacgaggct aaaattactg aatacaatcc ggcaaaatcg
    85501 cgcgaacagt tgaaggcgtt ggggctggaa aacttaacgc tgaaactgtg ggtgcccaca
    85561 cgttcgcagg cgtggaaccc cagtccactg aaaaccgccg aactgattca ggcggatatg
    85621 gcacaggttg gcgtaaaagt ggtgattgtg ccggtagaag gtcgttttca ggaggcgcgg
    85681 ttgatggata tgagccatga tctgacgtta tccggttggg cgacggacag taacgacccg
    85741 gacagtttct tccgtccgtt actgagctgc gcggcaattc attcacagac caacctcgcc
    85801 cactggtgcg atccgaaatt cgacagcgtg ttgcgtaagg cgctctcctc gcagcagctg
    85861 gcggcgcgta ttgaagccta tgacgaagcg caaagtattc tggcgcagga attacctatt
    85921 ctgccgctgg cgtcgtcatt gcgtttgcag gcctatcggt acgatatcaa aggtctggta
    85981 cttagcccgt ttggtaacgc ctcctttgct ggggtgtatc gcgagaaaca ggatgaggtg
    86041 aaaaagccat gattatcttc accttacgcc gtattttgtt attgattgtc accttgttcc
    86101 tgctgacctt cgttggcttc agcttgagct atttcacccc acatgcgccg ttacaaggcg
    86161 cgtcactgtg gaatgcctgg gtgttctggt ttaatggcct gatccactgg gattttggtg
    86221 tttccagcat taacggccaa ccgattgccg aacagttaaa agaggtcttc ccggcgacga
    86281 tggaactgtg catcctcgcc ttcggttttg cgctgattgt tggcatcccc gtggggatga
    86341 ttgccgggat tacgcgccat aagtggcagg ataacttgat caacgccatc gccttactgg
    86401 gcttttcaat cccggtgttc tggctggcgc ttctgttgac gctgttttgt tcactcacgc
    86461 taggttggtt gcccgtttct gggcgtttcg atttgctcta cgaagtgaaa ccgattaccg
    86521 gttttgcgtt gattgatgcc tggctttcgg actcaccgtg gcgggatgaa atggtcatga
    86581 gcgcaatccg ccatatgata ttacccgtga tcaccctgtc ggttgcgcca acaactgaag
    86641 tgatccgact aatgcgtatc agcactatcg aagtgtatga ccagaactat gttaaagcag
    86701 cggcgacccg cggtttgtcg cgctttacta ttttgcgtcg ccacgttctg cataacgcgt
    86761 tacctccggt tattcctcgc ctgggcttac agttttctac catgctgacg ctggcgatga
    86821 tcaccgaaat ggtttttagc tggccgggtt tagggcgctg gttaattaac gccatccgcc
    86881 agcaggatta cgcagccatt tccgccggag tgatggtgtg tggctcattg gtcattattg
    86941 ttaacgtgat ttctgatatt ttgggtgcca tggctaaccc tctgaaacat aaggaatggt
    87001 atgccttacg atagcgtata cagcgaaaag cgcccgccgg gcacgctgcg taccgcctgg
    87061 cgcaaatttt atagtgacgc ctctgcgatg gtcggcctgt acggctgcgc ggggctggct
    87121 gtactgtgta tttttggcgg ctggtttgcg ccttacggca tcgaccagca atttctcggt
    87181 taccaattat tgccgccgtc atggtcgcgc tatggcgaag tttctttctt cctggggact
    87241 gacgacctcg gacgcgatgt tttaagccgt ttactgagcg gagctgcgcc aaccgtaggt
    87301 ggcgcatttg tggtgacgct tgccgcgacg atctgtggcc tggttctggg caccttcgcc
    87361 ggggcgaccc acggcctccg ctcagcggtg cttaaccata ttctggatac cttactggcg
    87421 atcccttccc tactgctggc aattatcgtt gtagcgtttg ccggaccgag tttgtctcac
    87481 gccatgtttg ccgtctggct ggcgctgctg ccgcgtatgg tacgttcgat ttacagcatg
    87541 gtgcatgacg aactggaaaa agagtacgtt atcgccgccc gtctggatgg cgcatcaacg
    87601 ctgaatattc tctggtttgc tgtgatgcca aacatcaccg ccgggctggt caccgagatc
    87661 acccgcgcac tgtcgatggc aattctcgat atcgccgcgc tgggctttct cgatctcggc
    87721 gcacaactcc cctcgcctga atggggagcg atgctcggtg atgcgctgga actgatttat
    87781 gtcgccccgt ggactgtcat gctgccaggt gcggcaatta tgattagcgt gctgttggtt
    87841 aacctccttg gcgacggtgt ccgtcgtgca attattgcgg gggtggaata atgccattac
    87901 tcgatattcg taacctgacc attgaattta aaaccggtga tgagtgggtt aaagccgtcg
    87961 accgcgtaag tatgacctta accgaaggtg aaatccgcgg tcttgttggc gaatcaggtt
    88021 ccggcaaaag tttgattgcg aaagcgattt gtggggtgaa taaagataac tggcgtgtca
    88081 cagctgatcg tatgcgtttt gatgatatcg atttgctgcg tctctccgca cgcgaacggc
    88141 gcaagctggt tggtcacaac gtgtcgatga ttttccagga accgcagtcg tgtcttgacc
    88201 cttcagaacg tgtgggtcgc cagttgatgc aaaacatccc agcctggacc tataaaggcc
    88261 gttggtggca gcgttttggc tggcgcaaac gccgtgccat tgaactgctg caccgcgtgg
    88321 ggattaaaga tcacaaagat gcgatgcgca gttttcccta tgagttgacc gaaggtgaat
    88381 gtcagaaagt gatgatagcc attgcactgg cgaatcaacc gcgtctgctg attgctgacg
    88441 aaccgacaaa ctcaatggag ccaacaaccc aggcgcaaat ctttcgcctg ctgacgcgtc
    88501 tcaaccaaaa cagcaatacc actattttgc ttatcagcca tgacttacaa atgcttagcc
    88561 aatgggcgga taaaattaac gtgctttact gcggtcaaac ggtggaaacc gcgccaagta
    88621 aggagttggt gacaatgcca catcatcctt atacccaggc gctgatccgc gcgataccag
    88681 acttcggcag cgcgatgccg cataaaagtc gcctcaatac gctgcccggc gctatcccac
    88741 tgctggaaca gttaccgatt gggtgtcgtc tggggccgcg ttgcccgtat gcacaacgag
    88801 aatgcattgt gacgccacgt ttgacggggg cgaaaaatca tctctatgcc tgtcatttcc
    88861 cgctgaacat ggagaaagag tgagatgatc gaaacgctac ttgaagtgcg taatttaagt
    88921 aaaacgttcc gctaccggac cggctggttt cgtcgtcaga ccgtagaagc ggtaaaaccc
    88981 ttgagcttta cgctacgtga aggccagaca ctggcgatta ttggcgagaa tggttcgggt
    89041 aaatccacgc tggcaaaaat gctggcggga atgatagaac ctaccagcgg cgagttattg
    89101 attgacgatc atccgctgca ttttggcgat tattccttcc gcagtcagcg tattcgcatg
    89161 atttttcagg atccttcgac ctcgttgaat ccccgtcaac gtatctcgca aattctggat
    89221 tttccactgc gtctgaacac cgatctggaa ccggaacagc gtcgcaaaca gattattgaa
    89281 acgatgcgta tggttgggct gctaccggat cacgtcagtt actatccgca tatgttggca
    89341 cccgggcaaa aacagcgtct gggtctggcg cgcgcgctga tattgcgccc aaaagtcatt
    89401 attgccgatg aagccctcgc ctcactggat atgtcgatgc gttcgcagtt gattaacctg
    89461 atgctggagt tacaggaaaa acagggcatt tcgtatattt atgttaccca gcatatcgga
    89521 atgatgaagc acattagcga ccaggtgctg gtgatgcatc agggcgaggt tgtcgagcga
    89581 ggcagcaccg cggatgtgct ggcatcgccg ctgcatgaac tcaccaaacg gctgatcgcc
    89641 ggtcattttg gcgaggcatt gacggcggat gcgtggcgta aggaccgtta gtgttttgca
    89701 cctcatcctg acagggcccc cctcaggatg aggtgttcat tacttttgat tgtcgattct
    89761 ggtgagagca accagcaatg ccagcgtata acacaccgta attgccagac tcatttttaa
    89821 cagtgtttct ccgccaattc ccgacaatgg cgcggctata ccgccgaaga caaacatgct
    89881 catccccatc aacgcagacg ccgttccaga ttcctgcgtc cctactgcac tcatagcctc
    89941 tgccccgcca acagtgccga tgccgctaca aaatgcgatg gtgaaaaata atgccaccag
    90001 tgccggaatg ggcaattgta tccatgcgca taagaccgtg agcaatgcac acaaaattgc
    90061 cgctatcagg ccacctcgca acaatgtcat cgcgttaatc cggcgcgcca ggcgcgagaa
    90121 gatccatgaa gcaatgataa gtccgatgcc gttaaggcca aacaccaggc taaattgcat
    90181 tggactaaag ccaaattcct tctgcaacac gaacgacgaa gagccgatat atgcaaacaa
    90241 accggccagc ataaaacttt gaatcaggca aaagcgcata aaacggcggt tctgcaccac
    90301 gcttcgtccg gttaatagca atgatgagcc ccttttattt tctggcaagg tctcattaat
    90361 aaataacaga cagcccagca acagtacggt gctaatttca gccattaccc agaataaagt
    90421 gcgccagtca aaagtgctaa caatgtaccc gcccagcact ggcgacaaca ccggtgccag
    90481 gccattcacc gtcattaaca gcgcaaaaaa ctgggtcaac gttactccct gatatttgtc
    90541 acgagcaata gaacgagaga gcaccgaacc acccgccccc gcgatccctt gaataaaacg
    90601 ccagaccacc agccagtaaa tattgttcgt tgtcgcgcac aaaatggaag aaacaataaa
    90661 caatagcaac gacaagatta acggacgttt acgccctatt ttgtcgctca gagggccaaa
    90721 taacagttgt ccgacgccaa gaccaatcag tgatgcggtc agagttaatt gcgttatggt
    90781 cgtggttgcc gccagttgct cagacatctc cggcaaagcc ggcaaataaa gatcggtaca
    90841 catcgggccg ataccggcta aaagaccaag aatcaatgcc catgaaagag agactctagc
    90901 catattattc cttacttgag tgatgacatg ccgccgccca gcgactgcca gagcgtgatt
    90961 cggtttgtaa aatcagtcag ttgcagtgcc agcagctcct gctgtgcgct ccacaagctg
    91021 cgctgcgccg tcaacacggt caggtaatca ccaacacccg cctgatagcg acgcaagcca
    91081 acatcgaccg tttgttgttc agctttaaca tactggcgct gtgcatccag ttgctcttca
    91141 agcgtggtcc gccgcgccag tgcgttagcg acatctttaa atgcgctctg aacggttttt
    91201 tcataggtgg caatgagtcc acgcttttgt gcttctgcgt aacgaagctg cgccagatta
    91261 cttccgccag taaacagcgg taatgtgacc gatggcgcaa atgaccagat ctgcattccg
    91321 tggctgaaca acgacgacaa cgcgtcactg ccaacaccgg cactggcagt aagcgaaatc
    91381 gtcgggaaaa agttagcccg cgccgcgcca atatctgcat tggcgctctt caaattatgt
    91441 tccgcttcct ggatatccgg gcgacgcagc agaacatcag atgatactcc cgcaggaacc
    91501 agacttatca tttgttccgg caggctttcc agtgttcccg gtagcagatt ttccgcaagc
    91561 gttgtacctg ccagtaagtt cagcgcattt ttatcctgca tcacttgtgt ctgatagctg
    91621 gcaacgctgg cgcgcgcttg ctgataaaca ctcatcgcct cactgacatc tgtcgctgcc
    91681 gccgtgccaa cctgttgctg gcgctggata attttcaatg agttttctgc actggccatc
    91741 gtttcttttg ccagggccag gttgctgtta tcagccgcca gtgtcagcca ggcggtgctg
    91801 atttcagcaa tcagcgttaa acgagtgttc tgggctgtaa attcactggc aagccaggtt
    91861 tcccgcgccg cccgagataa actctgatta cgaccaaaca gatctaacgt ataactggac
    91921 accgtgccgt cagcctcggc agttgttccc gtaccattcg ccagcgaacg actgcgagtc
    91981 gaacttaagg ccgcattcac cgtcggaaat aacgacgcat tagtttgccc atagagcgcc
    92041 cgtgctgagt caatatcagc aatcgctttt tgcacatcgc ggttactgtt cagtgcaatg
    92101 gttactacct gctgcaatcg gggatcgtgg atcacctgct gccagtcatg gctgattgcc
    92161 ttcccctggc cctgtgctcc cggcaaggtc gccgggattg gggattcagg cgtgctgtag
    92221 tggggatcga gcgagacaca tcccgcactc aacagcacca gaaaaataag agagcgacgc
    92281 aacataactt actcctgacg gcgcggttta ccggcaaaca aacgtttcac cagtacaaaa
    92341 aacagaggaa caaagaaaat agccagcaac gtagcggtca gcgtaccgcc aataatgccc
    92401 gtaccaatgg cgatgcggct gttcgcccct gcgccggttg ctatcgccag cggcattacc
    92461 cccgcaataa acgccagcga ggtcatgatg attgggcgta aacgagtctg cgccgcgcgt
    92521 aatgccgcac gactcaagga atagccctct gcaaccgccg cttcagcaaa ttccacaatc
    92581 agaatggcgt ttttcgatga caagccgata gtagttaata gcgctacctg gaagtaaacg
    92641 tcgttgttta aatcacgcat ccaggccgcc agcgccgcgc caagaagccc cagagggatc
    92701 accagaatga ccgagaacgg gactgaccag ctttcgtaca gtgctgcaag gcagaggaaa
    92761 accaccagaa tagaaactgc atacagactt aatgcctgac cgctggccag tttctcctgc
    92821 aatgacaaac cactccaggc ccaggttgtt cccgcaggaa gactgtttgc cagttcctcc
    92881 atttttgtca ttgcatcgcc ggaactaaag ccagtcgcgt tttcgccctg aatttcatag
    92941 gctgccgagc cgttgtagcg caccagtctt tccggtccat acagccagcg ggtggtcgca
    93001 aaagcagaga atggtgtcat ggcgttatcg ctaccgcgca caaaccattt acctaagtct
    93061 gacggcgcgg aacgaaattc gctgtcgccc tgaatgtaga cttttttcac acgaccacgg
    93121 tcaataaagt cattcacata agtaccgccc cacgcactgg acagggtgtc ggtgacatca
    93181 ttcaaactca accctaatga caccgcttta ttgctatcaa tatctacctg caattgcggc
    93241 atttgtggca aatcattggc gcgtacagaa tgtaactccg gactttgatt cgctttttct
    93301 atcaactgat tacgcatttg cagcagtgtt tcacgatcgg ttccaccgtt agctaacaat
    93361 tcaaacgtaa aaccattgct ttgccccagc ccatcaacgg ctggcggcgt catcgcaaat
    93421 accgtggcat cacgaattgt gcccaactct ttggttgccc gtagggcgat agcctgggcg
    93481 gtgttttctg cccctttacg ttgagaccag tttttcaacg aaacaaacgc catcccggta
    93541 ttctgtccgc tgccgctaaa actgaaacca tcaacggtaa aaatgacatc ggtatttgct
    93601 ttctcgttaa tcaggaacca gtcaataatc tggcgattca cttctgctgt acgggcagcg
    93661 gtcgccccgg ccggcagcgt gtactgcacc atgatttcgc cctggtcttc agtgggtaag
    93721 aaactgcccg gcagtttcca catcatcagg gccattccac cacccagtac gacataaagc
    93781 cccatcgttc gagcagcacg gcgcaggaca taaattacgc ctcgctgata tttatcttca
    93841 gtacgacggt aaaagcggtt aaatgcgccg aaaaagcctt ttttatgtgg cggaacatgc
    93901 tggaggacgg aaccgcacag ggcgggagtc aaggtcaatg ccactaccac ggaaagcagc
    93961 attgcggaga taatggttat cgaaaactga cgataaatta cccccgtaga tcccccaaag
    94021 aaggccatag gcaggaatac ggctgacaac accagcgcaa tggcaaccag tgcgccagaa
    94081 atctcgccca ttgatttttc cgtggcttca cgcgcgggca acccttcgtc acgcataatg
    94141 cgttcaacgt tctccaccac cacaatggca tcgtccacca gcaagccgat cgccagcacc
    94201 attgcaaaca acgtcagggt attaatcgaa tagccaaaca acgcaagaac gccgaatgtg
    94261 cccagcaaaa cgacggggac agctaacgcc ggaatcagtg tggcacgcag gttttgcagg
    94321 aataaataca tcacgcaaac caccaatacg atggcttcaa acagcgtctg aattacgtcc
    94381 tctacggaga ttttaataaa ttcagtgctg tctttcgggt atgcgatgtc gtatccctgc
    94441 ggcatgttcc gctggaattc ggcaatctta tccttgacca gcgtcgccgt attcagcgca
    94501 ttcgcaccgg gcgaaagcat tacagcaacc ccggcagacg ggtgaccgtt aagtttgcca
    94561 atagcggtat aatcttcact gcccatctca acgcgagcca catcttttat acgaacaact
    94621 gcgccgtctg actggctttt cacgataata tttttgaact gatccaccgt ctgcaaacga
    94681 gactgcgcac gtaccgttgc ggtcagttgc tgagtatccg gtgaaggcaa tgcccctatt
    94741 ttcccggcag taacctgcac gttttgcgct tcaatagcac tttgcacgtc tgaaggcatc
    94801 agcgagtaag acgccagttt ggccgggtcg agccagatgc gcatagcgta ttccgcgcca
    94861 aagacttgca gactccccac accttcaaca cgcgccagcg ggtcctgaac gttactgacc
    94921 agccagtcgg cgatatccga actggaggct ttgtcagtgg tgtcatacac ggcagcaatc
    94981 agcaaaaagt tgctttgtga tttctccacc gtaacacccg tttgctgcac ttcgctgggt
    95041 aggcgcgact ccgcctgctg aattttattc tgcacctgaa cctgtgcagt atctggatcg
    95101 gtaccttgtt caaaggtcac attaatactg accgaaccat cagagctact ggttgagctg
    95161 aaatagagta aattatcaag cccagtgagt tgttgctcga taacctgagt cacgctgttc
    95221 tccagcgttt cggcagaagc accagtataa gtggctgaaa ttttaatggt cggcggtgca
    95281 acgtcaggat attgcgcgac gggcaatgtg cgaatagcca gaatccccgc caacataatc
    95341 aaaatggcga taacccaggc aaagaccggg cggcgaacaa aaaagcgcga aaacatcagg
    95401 cgttgcctcc attagcctga acttcaacag ccttgacggt ctgccctgaa gtgactttgg
    95461 cagaaccttc aacaatcagt cggtcgccgt tgtgcaggcc gttcagcacc agccatttat
    95521 caccatacgt ttctcccgtt tcgagcgttc gctgctctac tttattgtct ttattcacca
    95581 ccagcgcagt tgcattgcct ttagcatcgc gcgtaacgcc ctgttgaggc gcgagaatag
    95641 cgttttccat cacgccttca tcgacacgag cgcgaacaaa cattcccggt aataactgct
    95701 gttgtggatt ggggaaaatt gcccgtaatg tcaccgaacc ggtagactca tccaccgcaa
    95761 cttcggtgag ttccagacgc cctttttcgc tgtaggttgt gccatcttcc agaataagtg
    95821 agacgctcat ggtgtcactg ttggtcgcca gtgactgttt acgcagacgt aataaatcga
    95881 cactggagcg agtgaggtcg acatacattg tatccagacc acgaatagtc gttaacgctg
    95941 tatcctgcga cgcggtcacc agtgcgccag gggttaccga cgaaatacca atacgccccg
    96001 aaatcggtgc ggttaccgtg gtccagtcaa gattaatgcg cgcagtttcc agtgcggctt
    96061 ttttcgcctc tacactggct ttatcttgtg cacaggtaga ctgagcatca tcagcatcct
    96121 gttgtgaaac accattctct ttcaccagtc gggcataacg ctgcgctttc tggcaatcgg
    96181 cttttaccag tgcctgtgct tgttgtaatg ctgcccgggc ttcattccat gcagcctgat
    96241 aactggccgc atcaatctgg tagagaggct gtccagcctt gaccagatca ccttccttaa
    96301 ataagcgttt ctggataatt cccccaacct gcggacgtac ttcagcactg agcgcagcac
    96361 tggtgcgtcc ggttaattca ctgactaccg aaaccggttg agatttgagc gtaacaacgc
    96421 cgacttctgt ttctgacggg gatgaattgt tactttgcgt attatcacaa cccgataaga
    96481 gcagcattgc cactacagat gttgctatat acttcattat tttctccagg gtgagaaata
    96541 ccctcctcat taaaattaat gaggatatgt cagggatatt cagttataac gaacccgcat
    96601 cgcaaaatga atttcgcaat gaaataaggg ggattaatat cccccgctat tggttaattc
    96661 tgttcttatt tatttatcaa catactaaca atatcctgat atatttcctg cagatgttgt
    96721 ggatcgcttt tttgcggtgt taaacgacga taaaccgtac cttccatcat ggtagcaaac
    96781 acttcaacgc agcaacgaat gtgctcgtcg ctaagatggg gatgcattct tttcatatgt
    96841 gcacaaccgt tagcgaacat tctggcgtca gcttcttcaa gcattgccat aacccgcggg
    96901 ttgcgtgtgg cttctgcagc cacttccagc atcagcgcgt cgtcgtcctc atttaaggat
    96961 ttacgcaagg caaggacttc cgggaagtga tcggtacgcg cgtcaatgtc catttgggca
    97021 atacgaaagt cgatgatacg gcgaaccatc tcttcaataa tggcgtcttt gttggcgaag
    97081 taacgatata tctgacccac gctaagctga gcttcgctgg caatttgcga catactggcg
    97141 gcatgaaatc cgcagcgacg aaaacaccga cgggcggcgt taatgatttc atcctgacgc
    97201 tgtttgtggc gtatctccag cttgctggtc atttctgtct cctggcctat cacttggtga
    97261 gaatgatcgt tctcattttt gctgattata cgtttctcca aagtaatgga aagtattttt
    97321 atcttattca tggtgcatat tctgataatg aagagattgt ggagattctg tgaaaatagt
    97381 tgacaatatt aagttggggt caattcatca gaaaggcagc gacttgttgt cgccagttct
    97441 gttttcatca tcaaacttat cggagctaat acgaatagtt tcatagtcag attctataag
    97501 atatttcccc aacctacccc ttgcaggcgt caagagtaga taacgcaaaa tgctctgtac
    97561 cgcagcttct ctccgctaca gaaagcgcaa ctatagccac ccacagccag gttgattata
    97621 ataaccgttt atctgttcgt actgtttact aaaacgacga atcgcctgat tttcaggcac
    97681 aacaagcatc aacaataagg attaaagcta tgggttttct ttccggtaag cgcattctgg
    97741 taaccggtgt tgccagcaaa ctgtccatcg cctacggtat cgctcaggcg atgcaccgcg
    97801 aaggagctga actggcattc acctaccaga acgacaaact gaaaggccgc gtagaagaat
    97861 ttgccgctca attgggttct gacatcgttc tgcagtgcga tgttgccgaa gatgccagca
    97921 tcgacaccat gttcgctgaa ctggggaaag tttggccgaa atttgatggt ttcgtacact
    97981 ctattggttt tgcacctggc gatcagctgg atggtgacta tgttaacgcc gttacccgtg
    98041 aaggcttcaa aattgcccac gacatcagct cctacagctt cgttgcaatg gcaaaagctt
    98101 gccgctccat gctgaatccg ggttctgccc tgctgaccct ttcctacctt ggcgctgagc
    98161 gcgctatccc gaactacaac gttatgggtc tggcaaaagc gtctctggaa gcgaacgtgc
    98221 gctatatggc gaacgcgatg ggtccggaag gtgtgcgtgt taacgccatc tctgcgggtc
    98281 cgatccgtac tctggcggct tccggtatca aagacttccg caaaatgctg gctcattgcg
    98341 aagccgttac cccgattcgc cgtaccgtta ctattgaaga tgtgggtaac tccgcggcat
    98401 tcctgtgctc cgatctctct gccggtatct ccggtgaagt ggtccacgtt gacggcggtt
    98461 tcagcatcgc tgcaatgaac gaactcgaac tgaaataatc gttctgttgg taaagatggg
    98521 cggcgttctg ccgcccgtta tctctgttat acctttctga tatttgttat cgccgatccg
    98581 tctttctccc cttcccgcct tgcgtcagga taacgatttc ctttacgacc aaggagcgcc
    98641 catggaacaa cgccacatca ccggcaaaag ccactggtat catgaaacgc aatccagtac
    98701 tgcggagtat gacgttctac ctctggtccc ggaagccgca aaggtcagcg atccctttct
    98761 gctcgacgtg atccttgatg aagaaacgct ggcacccttc ctttcatggc tggtccctgc
    98821 gcgcgttctt gcagtagagt tgttccctga ccagcttacc gtgacccgtt cacagacctt
    98881 caccgcttat gaacgcttgt cgacggccct gacggttgct caggtttgcg gcgtccaacg
    98941 gttatgtaac tactattcgg cgcgacttac gccgctcccc gggcctgatt cctccaggga
    99001 aagtaatcat cggttagcac aaatcacgca atatgcccgc caactggcta gctcgccttc
    99061 tattatcgac aaccgatcgc gccagcatct gaatgacgtc ggcctaactg cctgggactg
    99121 tgtaatcatt aaccaaatca ttggttttat tggctttcag gcgcggtcaa ttgcgacatt
    99181 tcaggcttat ctcgggcatc cggtacgctg gttacccggt ctggagatac aaaactatgc
    99241 cgacgcgtca ctgtttgctg atgaatcaat acgctggcga agcagctatg aggtggaaaa
    99301 actccctgaa gagcacacaa aaagttcaac tgcagaactt tgccaactgg ccgaaacact
    99361 ctctctccac cctatttcac tttcccttct cgaaaagttg ctaaacagca cacgggtcaa
    99421 tacacagccg gataatcagc ttgcggcgtt gttatgcgcg cggataaatg gcagtcctgc
    99481 ttgttttgcc acctgtatgg attcatcaaa tgaatataaa aaaatcagcg cgggcgaaaa
    99541 tgaaattaac caatgggctg accgtcattc tgttgagcgc gctaccgttc aggcgataca
    99601 atggctgacc cgagcacccg atcgctttag cgccgcccag ttcagcccat tactcgaaca
    99661 cgaaaaatca tcaacgcaga ttattaatct gctggtatgg agcgggctgt gtggctggat
    99721 aaatcgctta aaaatcgcgt tgggtgagac atattaacct tgccgcgtca gacagattcg
    99781 cgtaaaactg tcagccgctc taatggccac caaaatagac aattatgttt caggacaacc
    99841 cgctgctagc gcagcttaaa cagcaactgc attcccagac gccacgcgct gaaggggtgg
    99901 taaaagccac agaaaaaggc tttggcttcc tggaagtcga cgcgcaaaaa agttatttca
    99961 ttccgccgcc gcagatgaaa aaagtcatgc atggcgaccg aattatcgcg gtgatccaca
   100021 gtgaaaaaga acgtgaatcc gcagagccag aagaactggt tgaaccgttc ctgactcgtt
   100081 tcgtgggtaa agttcagggc aaaaatgacc gtctggccat cgttcctgat catccactct
   100141 taaaagacgc cattccttgc cgcgcagccc gtggcctgaa ccacgagttt aaagaaggcg
   100201 actgggcggt tgccgaaatg cgccgtcatc cgctgaaagg cgatcgttct ttctatgctg
   100261 aactgacaca atacatcact tttggtgacg atcactttgt accgtggtgg gttacccttg
   100321 cgcgccataa tctggaaaaa gaagcaccag acggcgtcgc taccgaaatg ctcgatgaag
   100381 gtctggttcg tgaagatctg actgcgctgg attttgtcac catcgacagt gccagcacag
   100441 aagatatgga tgacgccctt ttcgctaagg cgttgccgga tgacaaactt cagctgattg
   100501 tggcgattgc cgatccaacc gcgtggattg ctgaaggcag caagctggac aaagccgcga
   100561 aaattcgcgc attcaccaac tatctgcctg gcttcaacat ccctatgctg cctcgcgagc
   100621 tttctgacga tctctgctca ctgcgcgcca atgaagtccg cccggtactg gcatgccgca
   100681 tgacgctctc cgctgatggc accattgaag ataatatcga attctttgcc gccaccatcg
   100741 aatccaaagc gaagctggtg tatgaccagg tttctgactg gctggaaaat accggtgact
   100801 ggcagcctga aagcgaagca attgccgaac aagtccgttt gctagcgcaa atttgccaac
   100861 gccgcggcga gtggcgtcat aaccacgcac tggtgtttaa agatcgcccg gattaccgct
   100921 ttattctcgg tgaaaaaggt gaagtgctgg atatcgtcgc cgagcctcgt cgcattgcca
   100981 accgtatcgt cgaagaagcg atgattgccg ctaacatttg tgcggcccgc gtactgcgcg
   101041 ataagctcgg ttttggcatc tataacgtgc atatgggctt tgatccggcg aatgccgacg
   101101 cgctggcagc gttgctgaaa acccacggtc tgcatgtcga tgccgaagaa gtgctcacgc
   101161 tggacggttt ctgcaaactg cgtcgtgaac tggatgcgca accaactggt ttcctcgaca
   101221 gccgcattcg tcgcttccag tcatttgctg aaattagcac tgaacccggt cctcactttg
   101281 gcctcggtct ggaggcatac gccacctgga cttcgccgat ccgtaaatat ggcgacatga
   101341 tcaaccaccg tctgctgaaa gcggttatca aaggcgaaac tgcgacgcgt ccgcaggatg
   101401 aaatcactgt ccaaatggcc gagcgtcgcc gtctcaaccg aatggcagaa cgtgatgttg
   101461 gcgactggtt atacgcacgc ttcctgaaag acaaagccgg gaccgacacc cgtttcgcgg
   101521 cggaaattgt cgatatcagc cgtggcggca tgcgtgttcg tttggttgat aacggcgcta
   101581 tcgcctttat tccggcacct ttcttacacg ctgtgcgcga tgaactggtt tgcagccagg
   101641 aaaacggcac tgtacaaatt aaaggtgaaa cggcttacaa agtgactgac gttattgacg
   101701 tcaccattgc cgaagtccgc atggaaaccc gcagcattat tgcgcgcccg gtcgcgtaat
   101761 ctcctttcac ggcccattcc tcatgaatgg gccgtttatt tccccgctcc accttcgtca
   101821 tatcccggca gattttttaa ctgactttcg tttgaaaact ggcgtttttc caaaactgga
   101881 ttacaaataa atatataaaa aaaacaatgc gtttagccgc cgttaatttc atgtaagtca
   101941 tgttgttcct tttatttaac cgcggactcc gctgttaacc ggaggatatg catcatgaaa
   102001 accgttaggg agtccacaac gttgtacaac tttctcggat cgcacaatcc atactggcgg
   102061 ttaacggaaa gcagcgatgt tttgcgcttt tctaccaccg aaaccacaga acctgatcgt
   102121 actttgcagt tatctgccga acaggctgct cgcatcaggg aaatgacggt catcacctcc
   102181 agcctgatga tgagtctgac cgtcgatgaa agcgatcttt ctgtgcatct ggtaggacga
   102241 aaaatcaata aacgggaatg ggctggcaac gcgtctgcat ggcatgacac accggcagtt
   102301 gctcgtgatt tatcacacgg gctttccttt gctgagcagg tagtttctga agcacattcc
   102361 gcaatagtga ttctcgacag ccgggggaat atccaacgct tcaatcggtt atgtgaagat
   102421 tacactgggt tgaaagaaca cgacgtcatt ggccaaagcg tgtttaaact gtttatgagc
   102481 cgtcgtgaag ctgcggcatc caggcgcaat aaccgtgtat tttttcgaag cggcaatgca
   102541 tatgaagtcg aactgtggat accaacacgt aaaggccagc ggctgtttct gtttcgcaat
   102601 aaatttgtcc acagcggcag tggcaagaac gagatttttt taatctgttc cggcaccgac
   102661 attaccgaag agcgccgcgc tcaggagcga ctgcgtattc tggcaaatac cgacagtatc
   102721 accggactgc cgaatcgtaa cgcaatgcag gagttaatcg atcacgctat taatcaggca
   102781 gataacaata aagttggggt tgtgtatctt gatttggata attttaaaaa ggtcaacgac
   102841 gcctatgggc atttatttgg tgaccagtta ttacgcgacg tgtcattggc cattttaagc
   102901 tgtctcgaac atgatcaggt gttggcgcgt ccaggtggcg atgagtttct ggtactggca
   102961 tccaatacct cacaaagcgc gctggaagca atggcatcac gaattttgac ccgcttacga
   103021 ctccccttcc gcattggttt aattgaagtt tataccagct gttcagtggg tatttcactc
   103081 tctcccgaac atggttcgga cagcgcggct attattcgtc acgccgacac agcaatgtac
   103141 acagcgaagg aaggcggacg aggacaattt tgcgttttta ctccagaaat gaatcagcgg
   103201 gtatttgaat atctctggct ggataccaac ttgcgtaaag cactggaaaa cgatcagttg
   103261 gttattcact atcaaccgaa aatcacctgg cgtggcgaag tgcgcagtct ggaagcacta
   103321 gtacgttggc agtcacctga acgtgggttg attccaccgt tggacttcat ttcctacgcc
   103381 gaagagtcag ggctaattgt gcctttaggc cgttgggtga ttctcgatgt cgtacgccag
   103441 gtggcaaagt ggcgggataa aggtattaac ctgcgagtgg cggtaaacat ttctgcacgt
   103501 cagctcgccg atcaaaccat tttcaccgcc ctgaaacagg ttctccagga actcaatttt
   103561 gaatactgcc ctattgatgt tgaactgacg gagagctgcc tgattgagaa tgatgaactt
   103621 gcactgtctg ttattcaaca atttagccaa ctaggtgcgc aagtgcatct ggacgatttt
   103681 ggtaccggct actcttcact ttcgcaactg gcgcgctttc cgatcgatgc catcaaactt
   103741 gaccaggttt ttgttcggga tattcacaaa cagcctgtct cgcagtcact ggtccgggcg
   103801 atcgttgctg tggcacaggc attgaatctt caggtgatcg ctgaaggtgt ggagagtaaa
   103861 aaggaagatg cttttttaac caagaacggg atcaatgagc ggcaaggatt tttgtttgcc
   103921 aaaccgatgc ccgccgtcgc cttcgaacgc tggtataaac gctatctgaa gcgcgcataa
   103981 gtagatgaat atatatactt agcgatatat tccgtcatta tatatcgtat tactggatga
   104041 taattagccg ttgctgttaa acacttctct tttagcggca atttttgcat tattcctttt
   104101 ccacttttgc tataaggatg tccttgatgt ctgaatttga tgcccagcgc gttgccgaac
   104161 gtattgatat tgtgttagat atccttgtgg caggcgatta ccactctgcg gtccataatc
   104221 tcgagatact taaagcagaa ctcttgcgcc aggttgctga atctacgcca gacatcccga
   104281 aggcaccgtg ggagatttaa caatcgtgcc ttcaggtttt cctatttgag gatgcccggc
   104341 gcgtcagtat ttttttattt agtattataa cgttataaga attacagcga tgaattcccg
   104401 acaacaaact attctacaga tggtcattga ccagggtcag gttagcgtaa ccgatctggc
   104461 aaaagccact ggagtttctg aagttaccat tcgccaggat ctcaacaccc tcgaaaaact
   104521 gagttacctc cgccgtgcac atggctttgc agtatcgctt gatagtgatg acgtcgaaac
   104581 tcgtatgatg agcaactata cgctgaagcg tgaactcgcc gagtttgccg cgtcactggt
   104641 tcaaccgggc gaaaccatct ttatcgaaaa tggcagcagc aatgccctgc tcgcccggac
   104701 tctgggcgag cagaagaaaa atgtcacgat catcacggtc agcagctaca tcgcgcattt
   104761 gctgaaagac gcgccttgtg aagttatttt gctcggtggc gtgtaccaga aaaaaagcga
   104821 aagtatggtt ggtccattga cacgccagtg catccaacag gtgcatttca gcaaagcatt
   104881 tattggtatt gatggctggc aacctgaaac tgggtttacc ggtcgcgata tgatgcgtac
   104941 cgatgtggtc aatgccgtgc tggaaaaaga gtgcgaggcg atagtcctga ctgacagctc
   105001 gaaatttggt gctgtacatt catactccat cggccccgtt gagcgattca atcgcgtgat
   105061 taccgattcg aaaatacgcg ccagcgatct gatgcatctt gagcacagta aactcaccgt
   105121 tcacgtcgtt gacatttaac catttccctt ctctacggat gatttgcagt ttggcaaatc
   105181 atccgctcta agatgattcc tggttgataa ttaagactat ttacctgtta ttaacactct
   105241 caagatataa aattattatc agcgatataa caggaagtca ttatcacctg cgtgatataa
   105301 ccctgcgcgc gagcggattt cacggaataa tttcaccagg cttattctta gctattatag
   105361 ttatagagag cttacttccg tgaatcataa attcaggaga gagtattatg tttgtaacga
   105421 gcaaaaaaat gaccgcggct gttctggcaa ttaccctggc aatgtctctg agtgcctgtt
   105481 ctaactggtc taaacgagac cgtaacaccg caattggcgc gggcgcaggt gcattaggcg
   105541 gtgcagtact gaccgatggc agtacgttgg gtacattagg tggtgcagcc atcggtggtg
   105601 ttattggtca ccaggtcggt aaataatcgt aaataaatgt cgattatcga ctcgcaatta
   105661 taatacgctt gattctgttc agtacgaaat aactgaataa tacacacagt aaaatattcg
   105721 aaagccacgg atatatccgt ggctttttat gttagccgcc tgcgagtttt accttcatcc
   105781 ctttcgcttc aagcagtgat tttaataaat cacgcttatc gccctggatt tcaataattc
   105841 catctttaac tgctccgccg cagccgcatt ttttcttcag ttccgctgcc agtttcgtca
   105901 gttcggcatc atcgagatcg acaccggtaa tcaggcaaac gcccttacct ttacgtccac
   105961 tggtctgacg ctgaatacgc accacaccgt cgcctttagg gcgtacaggg gccgcttttg
   106021 gctcatcaat acgtccggtt tccgttgagt agaccagacg gctgttggaa tcactcatca
   106081 tgcactccgc tgtaaagagg cgttgatcgc tttcagcgtc tgcgctggat ctaccgattg
   106141 cgttaccggg cgaccaatca ccatataatc aacaccagcc gccaacgcct gttctggcgt
   106201 cataatgcgg cgctggtcac ctgcttcact cccctgcgga cgaatgcccg gtgtaaccag
   106261 tttgaacgcc tgaccgaata cctgtttaaa gcgcacagct tcctgagcag aacacaccac
   106321 accatcaagg ccacattttt gcgtcagtgc cgccagacgt tctgcataat ctgcaggtga
   106381 cagtgtcacg ccaagatcgg ccaggtcgct ggcttccatg ctggtcaata ctgtcacagc
   106441 aatcaaaagc ggtgcatctt tgccaaacgg aaccagtgcc tcacgcgctg cggtcatcat
   106501 acgcgcccca ccggaggcgt gaacattcac catccacacg cctaagtcag ctgcagcagc
   106561 gacagcgtgc gctgcagtgt tgggaatatc gtgaaatttc aggtcgagga agatatcaaa
   106621 accacgctgt tgaagttcgc gtacaaattg aggtccaaac agcgtaaaca tctctttgcc
   106681 gactttcaga cgacaatcgc gtgggtcgat cttgtcgaca aaggccagcg cggcatcacg
   106741 attatgataa tcaagggcaa caaccacagg agaattcgta acagcgcggg aagaagatga
   106801 agcagttaac gtcatgacca gaccttcttg atgatgggca ccggaagtgg cgcgaaacag
   106861 gtaaacggcg agcattctac ccgtggaaat aaaaaattaa cagttgcgat ttctcctctg
   106921 gcaggctttt ccgcgccgtc ggtgccggag cacaatagaa catcaataat tagtatgttg
   106981 taactaaagt cggatttttt taaaaattac aggccatcaa gaccgcgaat cggtttaatg
   107041 gttgaccagg cccgacaaga cggacaatgc cagtagagag tgtatgcggt aaaaccacat
   107101 ttctggcagc gataacgagg cttactacgc accttctcgc caaccatgtc acgcagcacc
   107161 atcagactct ctttggcacg cccttcttct gcttcattta agtggtaatc cattaactta
   107221 tggaacacac gcatggtcgg atgacgctga agctggcgcg taatatagac ctgtgcggcc
   107281 tcactaccgt cgcgcgcttc gatgatgtcc gcaagcatca gttcagcatc ggcaccggtg
   107341 ttctcttcca ccgcgcgctg caggaactct gcccattcgg cagttttacc caactgctgg
   107401 tagcaggttt gcagcatttc cagcgtttcg ctgaccagtt ctctgtcctg ggatatgaca
   107461 cgttgcaaac tttcgacggc tttggcgtat tctcctttcg ccataaacac gcgtcccatc
   107521 atgatggata cgcgggcgct gtttttatct gccgccgcac ctttttttag caaagtcatg
   107581 gcacgatcga gatcgtcgct ggccatatgc tgcagagcta actcacagta gaaatgggca
   107641 atttcgacgc gctgtttatc tttacccagc ttcaccaggc gttcggcaac atcaattgct
   107701 ttctgccact cgctggtagc ctggtagatt tgtagcaact gttgcagcgc gccaatgcgg
   107761 aagtcagttt catctgtcag ctgattgaac atgtcttccg cgcggtcgta taacccggca
   107821 gccatgtaat cacgccccag ttgttgaatc gccaaaagcc gctgttcata ggtcagcgag
   107881 gcgctttcca ttagggtctg atggatgcga atagcgcgat caacttcgcc acgcgaacgg
   107941 aacaggtttc cgagcgtaag gtgggcttca acggtacctg tatcctcttt aagcatatcg
   108001 agaaacaggt ctaccgcttt atcctgttga ttactaagca ggaagttaac ccccgctacg
   108061 taatcacgcg acaagcggtt ggcttcatct tgcttgtttt gttgcgcact tctgcggccc
   108121 atataccagc cataggcagc ggctacaggc aaaagcagaa acaacaactc cagcatagaa
   108181 agttattcct tcgacgcaga cgagtgcggc gctacagcca cgtcagtcgc gggtgaaagc
   108241 tggttttcca gtcgctttat tttacgttca gcgcgcgcca gggaaacacg aactcgcagc
   108301 cagaaaaggc cgcaaatcag ccaaccgata gcaaaccccg cagcaaacaa taccgccagc
   108361 aatgtggaaa tacggtactc cccttgcgct aacagataat taaacgtcac ctgttgatcg
   108421 ttctgcgcac ctaacgtaac cgaaatcacg aagatcgcta acaccagtaa gaaaatgagt
   108481 aaatatttca cattacttcc cgttatgtgg ttagagcgaa taaattatgg tcaacttacc
   108541 gcaatagccc tttaaagtac cattttcgcg ccgtctgcga aatggcatcc acgcgtattg
   108601 ttgatgattt aagggctaaa ttcggaaaat caaccagcgt taactttctt gttctcgttg
   108661 tgcaatttcg cgattttctt ccgcaggtgg tgttaatggc ccacaaattc gttgcgcaag
   108721 ccacgttgcc accgccacca gcgcccacga aatcaacgta gctaccacca gatcgcgtgg
   108781 ccaatgcatc ccgagcagca ggcggcttcc catgactccc gttgcccaga ccaacaagat
   108841 agcaatggtt aacgttcgcc gacgcggcca cagcaaacca acggccagca gtgcccaact
   108901 ggcagcaaac atcgtgtgac cggaaggaaa agcaaacccc gtctctttct gccagtgtga
   108961 acgcaaatat tgtgggatat ttttctcttc agccaactgt tctttcacca gatttccgcg
   109021 ttctgctcgc tttaaagtgt agaactcatc aaccggaata tgatgtgttt tttccagcca
   109081 gataacaaaa ggtcgtggtt cctggacttt gtctttgatc caggatttaa cgccttgtcc
   109141 cacaagaatt gccgccgcca gaatggcaaa taacataatg gcagccttaa tgcgaaaacg
   109201 cagacaccag agaaaccagc cgaataaaat caaatgtgta atgacgcccc agggctgggt
   109261 gacagtttca gtaacccaaa aagccgcttt tagtaaccaa ctttgttctc caggttgcca
   109321 acgccagcca gaaatccata cggctactgg cataacaagc aatagtgcag ttcccactgc
   109381 ggtacgtctg gcaatcgaac gcatggcctc tcctttttga taagtcccac aatcataact
   109441 gaaaatgcca gttccaggaa aaattgacag atttgtgcca ttccgtgaac gatcgacgcg
   109501 tcgtgattag gtgaacccct tctcgttatg gcaaaataag ccaatacaga accagcatta
   109561 tctggagaat ttcatgcagc ttaaacgtgt ggcagaagcc aaactgccaa ccccatgggg
   109621 cgatttcctg atggtgggat ttgaagaact ggcaaccgga cacgatcatg tcgcgctagt
   109681 ctatggcgat atttccgggc ataccccggt acttgcgcgc gtccattccg aatgtctgac
   109741 cggtgacgcc ctgttcagct tgcgctgcga ttgtggcttc cagctcgaag cggcactgac
   109801 gcaaattgcc gaagaaggcc gtggtatttt gctgtatcac cgtcaggaag gtcgtaacat
   109861 tggtctgctg aataaaatcc gcgcttatgc actgcaggat caaggttacg atactgtaga
   109921 ggctaaccac cagttaggct tcgccgctga tgagcgcgac ttcactcttt gcgctgatat
   109981 gttcaaactc cttggcgtca atgaagtccg cttgttaacc aacaacccga aaaaagtcga
   110041 aattctgacc gaagcaggga ttaatattgt tgaacgcgta ccgttgattg taggtcgtaa
   110101 ccccaataac gaacattatc tcgataccaa agccgagaaa atgggtcatt tgctgaacaa
   110161 ataaccctct tgcattgtgt aattaatttg cttgccggaa gcaaaataac cggcaagcaa
   110221 atactcgtta cttcaacata ttacgaatga cataatgcaa aatgccgtcg ttctggtagt
   110281 aggtcaactc cgtcgcggtg tcgatacgac aacggcaggg tacgacttcc tggctaccat
   110341 ccgcgcgcgt aagcgtcacc ggaaccgtcg caccgggctg taaattttgc agatcgccaa
   110401 tatcaatctt ctcttccccg gttagcccta acgttttacg cgttacgcct tgcggaaatt
   110461 ccagcggcag gatgcccatg ccaattaaat tcgaacggtg aattcgttca aacgattcgg
   110521 caatcaccac acgaattcca agcagacgag gaccttttgc cgcccagtca cggctggagc
   110581 ctgatccata ctctttcccg gcaatcaccg ccagcggcgt ttgttcctgc ttatagcgca
   110641 tcgcagcatc ataaatagag actacgtcgc tgtcaggtaa atgccgcgtc atcccccctt
   110701 caacgccagg caccatttca ttacggatgc gaatattggc gaaggtgccg cgcatcatca
   110761 cttcatggtt accacgccgc gaaccgtagg agttaaagtc tttgcgctca acaccccgac
   110821 cttgtagata tcgccccgct gggctgtcgg gcttaatact gcccgccgga gagatatggt
   110881 cagtggtgac tgaatccccc agcattgcga ggatccgcgc accgtgaata tcttccacag
   110941 gtgctggtgt tgcctgcatt tcatcaaaga aaggcgataa gcgaatatag gttgaatcct
   111001 cctgccaacc gtaggtatcg gatcgtgcga cgttaatttc cttccactct gctgtgcctt
   111061 caaaaacttc tgcgtactct ttacggaaca tttctgtgga gacttgttct accgcacggg
   111121 caatttcttg tgccgatggc cagatatctt tcagatatac cggatcgcct ttgcgatcat
   111181 ggccgatagg ctcagatgcg aggttaatat tcatatttcc cgccagcgca taggcaacca
   111241 ccagcggcgg cgaggccagc cagttagttt taaccagcgg atggatacgg ccttcaaagt
   111301 tacggttgcc ggacagcacc gcaccgacgg ttaaatcgcc ttttttgatt gccgtttcga
   111361 taggatcggg caatggacca gagttaccaa tacaggtggt acaaccgtat cccacaaggt
   111421 taaaccccag ttcatcgaga tacggtgtca atttcgcttt tgccagataa tcagaaacga
   111481 ctttcgaacc cggtgccagc gacgctttga cccacggttg ccgcttgagg cccagtgtta
   111541 cagctttttt cgccagcaaa cctgcggcca tcagcacact tgggttagag gtgttggtgc
   111601 acgaggttat cgcagcaatg accaccgcgc catcaggtaa ctgatactga tgtccgttca
   111661 taacataatc gaccggctgg cgatctttat gcgtggcatt tacttccagt tcgttactgg
   111721 cggcaaatgc ttttggtaca tcgggcagtg caacgcgatc ctgtgggcgt tttggccctg
   111781 ccaggctcgc ttcaacgtca ttcatatcca gttctaacgt actggtaaaa atcggttcat
   111841 cgcccgggtt acgccacatg ccctgcgctt tggcatattt ttcgaccaac tcgacctgat
   111901 cttcgctgcg cccgcttaaa cgcatgtaat cgagggtgac agcatcgatt gggaagaagc
   111961 cacaggtcgc accatattct ggcgacatat tggcaatggt ggcgcgatcc gccagcggta
   112021 gtgaatccag cccatcacca taaaattcga cgaatttccc caccacgcca tgtttgcgca
   112081 gcatttgggt aacggtgaga accaggtctg tggcggtaat accttcacgt aattttccgg
   112141 taagtttaaa gcctactacg tccgggataa gcatggaaac cggctggcct aacattgcgg
   112201 cttcggcttc gatcccacca acgccccacc ccagcacgcc aaggccgttg atcatggtgg
   112261 tgtgcgagtc agtaccaacg agtgtatccg gataagcaat ccattcaccg tcctgcaatt
   112321 cgctccacac tgctttgccg agatattcga ggttaacctg atggcaaatg cctgtgcctg
   112381 gcggcacgac gctaaaacga ctgaacgcct gctttcccca tttcaggaac acataacgtt
   112441 cgtggttgcg ctccatttcc aggcgcacgt tttcttcaaa tgcctcatca tcaccaaaac
   112501 gatcgacggt caccgagtgg tcaatgacca ggtcgaccgg tgagagcggg ttaacctttg
   112561 cagtatcgcc gccgaggcgt ttaaccgctt cgcgcattgc cgccagatca acaacggcag
   112621 gtacgccggt aaagtcctgc atcagcaccc ttgccgggcg gtaggcaatt tcacggtcag
   112681 catgggcatt tttcagccat cccgccagcg cgtagatatc ctcttcggta accgagttac
   112741 catcctgcca gcgcagcagg ttttcgagca aaactttgag tgacttgggc agacgggtga
   112801 tatcgcccag tgatttggca gcaagcggca ggctgtagta gtggtaagtt ttatctttgg
   112861 cctgtaacgt gtccttactg gcttctcgta gggttgacga catagctcct ccttaatgac
   112921 agggttgcga cgccctgatt ctcttcaggg tgaatattaa agataacaca aacatcgcgt
   112981 aacgatttga taacaaccca aattgataaa agaggagaaa ccttgtggca aagcaaatga
   113041 aaacccccgc cgcagcgggg tcagggatta gtgagtaatg atccagagga gttcagccca
   113101 gaagagcatc gacagagaaa acgcgcccat ccaggaccaa tatttcatat ttgtgttgat
   113161 cataggctac acccttaacg gttattactt tgtgttgaga taactcaacc tgttattgct
   113221 gcggtgtatt aaaagccctg taattcatta aaaatgggta ataagaatga tgataattat
   113281 tgtttcggct gatcatcttc agcaaacagt tctataaagg cttgctgctg cgatgttagt
   113341 tgccagtcgt ctggaataac gacggaacat tcccgtttcg tttctggttc attatcacta
   113401 tgctgacata atggtgacga ctccagttgc tcctgaccga ccatagttat ccccacactt
   113461 tccaaatcag cagtgcgata accacccaga aaagtgcaga accaagaaaa accgccagcc
   113521 aggctttacg ttttaattca ggatcgcggc ggggttcctg atttccagaa ggcattgcta
   113581 acctcatata atcgccatca cttatcagca agacgttgaa cgattggtgt aattaatcat
   113641 acgatgagac aaatcctaaa gaaactttag tcaaaaatcc agcgaattta cgaatcgtcg
   113701 ccagtgaata attcaatctt ttgacctgaa atagatattt gaaaacggga atttgcta
//
LOCUS       DADXDL010000005       108129 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.005, whole genome shotgun sequence.
ACCESSION   DADXDL010000005 DADXDL010000000
VERSION     DADXDL010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 108129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 108129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..108129
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.005"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(6..113)
                     /gene="rprA"
                     /locus_tag="IRB70_000435"
     ncRNA           complement(6..113)
                     /ncRNA_class="antisense_RNA"
                     /gene="rprA"
                     /locus_tag="IRB70_000435"
                     /product="antisense sRNA RprA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00034"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00034"
     gene            complement(299..1411)
                     /gene="ydiK"
                     /locus_tag="IRB70_000436"
     CDS             complement(299..1411)
                     /gene="ydiK"
                     /locus_tag="IRB70_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter YdiK"
                     /protein_id="HBC0630393.1"
                     /translation="MVNVRQPRDVAQILLSVLFLAIMIVACLWIVQPFILGFAWAGTV
                     VIATWPVLLRLQKFMFGRRSLAVLVMTLLLVMVFIIPIALLVNSIVDGSGPLIKAISS
                     GDMTLPDLAWLNTIPVIGAKLYAGWHNLLDMGGTAIMAKVRPYIGTTTTWFVGQAAHI
                     GRFMVHCALMLLFSALLYWRGEQVAQGIRHFATRLAGVRGDAAVLLAAQAIRAVALGV
                     VVTALVQAVLGGIGLAVSGVPYATLLTVLMILSCLVQLGPLPVLIPAIIWLYWTGDTT
                     WGTVLLVWSGVVGTLDNVIRPMLIRMGADLPLILILSGVIGGLIAFGMIGLFIGPVLL
                     AVSWRLFAAWVEEVPPPTDQPEEILEELGEIEKSNK"
     gene            1800..4856
                     /locus_tag="IRB70_000437"
     CDS             1800..4856
                     /locus_tag="IRB70_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBC0630394.1"
                     /translation="MIPQISQAPGVVQLVLNFLQELEQQGFTGDTATSYADRLTMSTD
                     NSIYQLLPDAVVFPRSTADVALIARLAAQERYSSLIFTPRGGGTGTNGQALNQGIIVD
                     MSRHMNRIIEINPEEGWVRVEAGVIKDQLNQYLKPFGYFFAPELSTSNRATLGGMINT
                     DASGQGSLVYGKTSDHVLGVRAVLLGGDILDTQPLPVELAETLGKSNTTIGRIYNTVY
                     QRCRQQRQLIIDNFPKLNRFLTGYDLRHVFNDEMTEFDLTRILTGSEGTLAFITEARL
                     DITRLPKVRRLVNVKYDSFDSALRNAPFMVEARALSVETVDSKVLNLAREDIVWHSVS
                     ELITDVPDKEMLGLNIVEFAGDDEALIDERVSALCARLNELIASQQAGVIGWQVCSEL
                     AGVERIYAMRKKAVGLLGNAKGAAKPIPFAEDTCVPPEHLADYIAEFRALLDSHGLSY
                     GMFGHVDAGVLHVRPALDMCDPQQEILMKQISDDVVALTAKYGGLLWGEHGKGFRAEY
                     SPAFFGEELFAELRKVKAAFDPHNRLNPGKICPPEGLDAPMMKVDAVKRGTFDRQIPI
                     AVRQQWRGAMECNGNGLCFNFDARSPMCPSMKITQNRVHSPKGRATLVREWLRLLADR
                     GVDPLKLEQELPESGVSLRTLIARTRNSWHANKGEYDFSHEVKEAMSGCLACKACSTQ
                     CPIKIDVPEFRSRFLQLYHTRYLRPLRDHLVATVESYAPLMARAPKTFNFFINQPLVR
                     KLSEKHIGMVDLPLLSVPSLQQQMVGHRSANMTLEQLEALNAEQKARTVLVVQDPFTS
                     YYDAQVVADFVRLVEKLGFQPVLLPFSPNGKAQHIKGFLNRFAKTAKKTADFLNRMAK
                     LGMPMVGVDPALVLCYRDEYKLALGEERGEFNVLLANEWLASALDSQPVATVSGESWY
                     FFGHCTEVTALPGAPAQWAAIFARFGAKLENVSVGCCGMAGTYGHEAKNHKNSLGIYE
                     LSWHQAMQRLPRNRCLATGYSCRSQVKRVEGTGVRHPVQALLEIIK"
     gene            4853..5263
                     /gene="menI"
                     /locus_tag="IRB70_000438"
     CDS             4853..5263
                     /gene="menI"
                     /locus_tag="IRB70_000438"
                     /EC_number="3.1.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA hydrolase"
                     /protein_id="HBC0630395.1"
                     /translation="MIWKRKITLEALNAMGEGNMVGLLDIRFEHIGDDTLEATMPVDS
                     RTKQPFGLLHGGASVVLAESIGSVAGYLCTEGEQKVVGLEINANHVRSAREGRVRGVC
                     KPLHLGSRHQVWQIEIFDEKGRLCCSSRLTTAIL"
     gene            5363..5551
                     /locus_tag="IRB70_000439"
     CDS             5363..5551
                     /locus_tag="IRB70_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416200.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiH family protein"
                     /protein_id="HBC0630396.1"
                     /translation="MSTQLDPTQLAIEFLRRDQSNLSPAQYLKRLKQLELEFADLLTL
                     SSAELKEEIYFAWRLGVH"
     gene            6100..6468
                     /gene="sufA"
                     /locus_tag="IRB70_000440"
     CDS             6100..6468
                     /gene="sufA"
                     /locus_tag="IRB70_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly scaffold SufA"
                     /protein_id="HBC0630397.1"
                     /translation="MDMHSGTFNPQDFAWQGLTLTPAAAVHIRELVAKQPGMVGVRLG
                     VKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFIDGTEVDFVREGLNQI
                     FKFHNPKAQNECGCGESFGV"
     gene            6477..7964
                     /gene="sufB"
                     /locus_tag="IRB70_000441"
     CDS             6477..7964
                     /gene="sufB"
                     /locus_tag="IRB70_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416198.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBC0630398.1"
                     /translation="MSRNTEATDDVKTWTGGPLNYKEGFFTQLATDELAKGINEEVVR
                     AISAKRNEPEWMLEFRLNAYRAWLEMEEPHWLKAHYDKLNYQDYSYYSAPSCGNCDDN
                     CASEPGAVQQTGANAFLSKEVEAAFEQLGVPVREGKEVAVDAIFDSVSVATTYREKLA
                     EQGIIFCSFGEAIHDHPELVRKYLGTVVPGNDNFFAALNAAVASDGTFIYVPKGVRCP
                     MELSTYFRINAEKTGQFERTILVADEDSYVSYIEGCSAPVRDSYQLHAAVVEVIIHKN
                     AEVKYSTVQNWFPGDNNTGGILNFVTKRALCEGENSKMSWTQSETGSAITWKYPSCIL
                     RGDNSIGEFYSVALTSGHQQADTGTKMIHIGKNTKSTIISKGISAGHSQNSYRGLVKI
                     MPTATNARNFTQCDSMLIGANCGAHTFPYVECRNNSAQLEHEATTSRIGEDQLFYCLQ
                     RGISEEDAISMIVNGFCKDVFSELPLEFAVEAQKLLAISLEHSVG"
     gene            7974..8720
                     /gene="sufC"
                     /locus_tag="IRB70_000442"
     CDS             7974..8720
                     /gene="sufC"
                     /locus_tag="IRB70_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBC0630399.1"
                     /translation="MLSIKDLHVSVEDKAILRGLSLDVRPGEVHAIMGPNGSGKSTLS
                     ATLAGREDYEVTGGTVEFKGKDLLALSPEDRAGEGIFMAFQYPVEIPGVSNQFFLQTA
                     LNAVRSYRGQETLDRFDFQDLMEEKIALLKMPEDLLTRSVNVGFSGGEKKRNDILQMA
                     VLEPELCILDESDSGLDIDALKVVADGVNSLRDGKRSFIIVTHYQRILDYIKPDYVHV
                     LYQGRIVKSGDLTLVKQLEEQGYGWLTEQQ"
     gene            8695..9966
                     /gene="sufD"
                     /locus_tag="IRB70_000443"
     CDS             8695..9966
                     /gene="sufD"
                     /locus_tag="IRB70_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBC0630400.1"
                     /translation="MAGLPNSSNALQQWHHLFEAEGAKRSPQAQQHLQQLLRTGLPTR
                     KHENWKYTPLEGLTNSRFVSIAGEISPQQRDALALTLDAVRLVFVDGRYVPALSDATE
                     GSGYEVSINDDRQGLPDAIQAEVFLHLTESLAQSVTHIAVKRGQRPAKPLLLMHITQG
                     VAGEEVNTAHYRHHLDLAEGAEATVIEHFVSLNDARHFTGARFTINVAANAHLQHIKL
                     AFENPVSHHFAHNDLLLADDATAFSHSFLLGGAVLRHNTSTQLNGENSTLRINSLAMP
                     VKNEVCDTRTWLEHNKGFCNSRQLHKTIVSDKGRAVFNGLINVAQHAIKTDGQMTNNN
                     LLMGKLAEVDTKPQLEIYADDVKCSHGATVGRIDDEQMFYLRSRGINQQDAQQMIIYA
                     FAAELTEALRDEGLKQQVLARIGQRLPGGAR"
     gene            9963..11183
                     /gene="sufS"
                     /locus_tag="IRB70_000444"
     CDS             9963..11183
                     /gene="sufS"
                     /locus_tag="IRB70_000444"
                     /EC_number="2.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase SufS"
                     /protein_id="HBC0630401.1"
                     /translation="MTFSVDKVRADFPVLSREVNSLPLAYLDSAASAQKPSQVIDAEA
                     EFYRHGYAAVHRGIHTLSAQATEKMENVRKRASLFINARSAEELVFVRGTTEGINLVA
                     NSWGNSNVRSGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLEMLPNL
                     FDEKTRLLAITHVSNVLGTENPLAEMITLAHQHGAKVLVDGAQAVMHHPVDVQALDCD
                     FYVFSGHKLYGPTGIGILYVKEALLQEMPPWEGGGSMIATVSLSEGTTWTKAPWRFEA
                     GTPNTGGIIGLGAALEYVSALGLNNIAEYEQNLMHYALAQLESVPDLTLYGPQNRLGV
                     IAFNLGKHHAYDVGSFLDNYGIAVRTGHHCAMPLMAYYNVPAMCRASLAMYNTHEEVD
                     RLVTGLQRIHRLLG"
     gene            11196..11612
                     /gene="sufE"
                     /locus_tag="IRB70_000445"
     CDS             11196..11612
                     /gene="sufE"
                     /locus_tag="IRB70_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfuration protein SufE"
                     /protein_id="HBC0630402.1"
                     /translation="MALLPDKEKLLRNFLRCANWEEKYLYIIELGQRLPELRDEDRSP
                     QNSIQGCQSQVWIVMRQNAQGIIELQGDSDAAIVKGLIAVVFILYDQMTPQDIVNFDV
                     RPWFEKMALTQHLTPSRSQGLEAMIRAIRAKAAALS"
     gene            11761..12765
                     /gene="ldtE"
                     /locus_tag="IRB70_000446"
     CDS             11761..12765
                     /gene="ldtE"
                     /locus_tag="IRB70_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtE"
                     /protein_id="HBC0630403.1"
                     /translation="MKRASLLTLTLIGAFSAIQAAWAVDYPLPPTGSRLVGQNQTYTV
                     QEGDKNLQAIARRFDTAAMLILEANNTIAPVPKPGTTITIPSQLLLPDAPRQGIIVNL
                     AELRLYYYPPGENIVQVYPIGIGLQGLETPVMETRVGQKIPNPTWTPTAGIRQRSLER
                     GIKLPPVVPAGPNNPLGRYALRLAHGNGEYLIHGTSAPDSVGLRVSSGCIRMNAPDIK
                     ALFSSVRTGTPVKVINEPVKYSVEPNGMRYVEVHRPLSAEEQQNVQTMPYTLPAGFTQ
                     FKDNKAVDQKLVDKALYRRAGYPVAVSSGATPAASNTPSVESAQNGEPEQGNMLRATQ
                     "
     gene            complement(12829..13065)
                     /gene="lpp"
                     /locus_tag="IRB70_000447"
     CDS             complement(12829..13065)
                     /gene="lpp"
                     /locus_tag="IRB70_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein lipoprotein Lpp"
                     /protein_id="HBC0630404.1"
                     /translation="MKATKLVLGAVILGSTLLAGCSSNAKIDQLSSDVQTLNAKVDQL
                     SNDVNAMRSDVQAAKDDAARANQRLDNMATKYRK"
     gene            complement(13376..14788)
                     /gene="pykF"
                     /locus_tag="IRB70_000448"
     CDS             complement(13376..14788)
                     /gene="pykF"
                     /locus_tag="IRB70_000448"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010346010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase PykF"
                     /protein_id="HBC0630405.1"
                     /translation="MKKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHG
                     QRIQNLRNVMSKTGKTAAILLDTKGPEIRTMKLEGGNDVSLKAGQTFTFTTDKSVIGN
                     SEMVAVTYEGFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNL
                     PGVSIALPALAEKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHII
                     SKIENQEGLNNFDEILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVIT
                     ATQMLDSMIKNPRPTRAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICER
                     TDRVMNSRLEFNNDNRKLRITEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFP
                     DATILALTTNEKTAHQLVLSKGVVPQLVKEITSTDDFYRLGKELALQSGLAHKGDVVV
                     MVSGALVPSGTTNTASVHVL"
     gene            15345..15554
                     /gene="fumD"
                     /locus_tag="IRB70_000449"
     CDS             15345..15554
                     /gene="fumD"
                     /locus_tag="IRB70_000449"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate hydratase FumD"
                     /protein_id="HBC0630406.1"
                     /translation="MGNRTKEDELYREMCRVVGKVVLEMRDLGQEPKHIVIAGVLRTA
                     LANKRIQRSELEKQAMETVINALVK"
     gene            16010..16636
                     /locus_tag="IRB70_000450"
     CDS             16010..16636
                     /locus_tag="IRB70_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein"
                     /protein_id="HBC0630407.1"
                     /translation="MNPVDRPLLDIGLTRLEFLRISGKGLAGLTIAPALLSLLGCKQE
                     DIDSGTVGLINTPKGVLVTQRARCTGCHRCEISCTNFNDGSVGTFFSRIKIHRNYFFG
                     DNGVGSGGGLYGDLNYTADTCRQCKEPQCMNVCPIGAITWQQEEGCITVDHKRCIGCS
                     ACTTACPWMMATVNTESKKSSKCVLCGECANACPTGALKIIEWKDITV"
     gene            16657..18759
                     /locus_tag="IRB70_000451"
     CDS             16657..18759
                     /locus_tag="IRB70_000451"
                     /EC_number="1.2.7.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde ferredoxin oxidoreductase"
                     /protein_id="HBC0630408.1"
                     /translation="MANGWTGNILRVNLTTGNITLEDSSKFKSFVGGMGFGYKIMYDE
                     VPPGTKPFDEANKLVFATGPLTGSGAPCSSRVNITSLSTFTKGNLVVDAHMGGFFAAQ
                     MKFAGYDVIIIEGKAKSPVWLKIKDDKVSLEKADFLWGKGTRATTEEICRLTSPETCV
                     AAIGQAGENLVPLSGMLNSRNHSGGAGTGAIMGSKNLKAIAVEGTKGVNIADRQEMKR
                     LNDYMMTELIGANNNHVVPSTPQSWAEYSDPKSRWTARKGLFWGAAEGGPIETGEIPP
                     GNQNTVGFRAYKSVFDLGPAAEKYTVKMSGCHSCPIRCMTQMNIPRVKEFGVPGTGGN
                     TCVANFVHTTIFPNGPKDFEDKDDGRVIGNLVGLNLFDDYGLWCNYGQLHRDFTYCYS
                     KGVFKRVLPAEEYAEIRWDQLEAGDVNFIKDFYYRLAHRVGELSHLADGSYAIAERWN
                     LGEEYWGYAKNKLWSPFGYPVHHANEASAQVGSIVNCMFNRDCMTHTHINFIGSGLPL
                     KLQREVAKELFGSEDAYDETKNYTPINDAKIKYAKWSLLRVCLHNAVTLCNWVWPMTV
                     SPLKSRNYRGDLALEAKFFIAITGEDMTQEKLDLAAERIFTLHRAYTVKLMQTKDMRN
                     EHDLICSWVFDKDPQIPVFTEGTDKMDRDDMHASLTMFYKEMGWDPQLGCPTRETLQR
                     LGLEDIAADLAAHNLLPA"
     gene            18772..19410
                     /locus_tag="IRB70_000452"
     CDS             18772..19410
                     /locus_tag="IRB70_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310406.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdhW family putative oxidoreductase system
                     protein"
                     /protein_id="HBC0630409.1"
                     /translation="MNHKDELPLAEVSEIDEAKRQWLQGMRHPVDTVTEPEPAEILAE
                     FIRQHSAAGQLVARAVFLSPPYSVAEEELSVLLENIKQNGDYADIACMTGSQDDYYYS
                     TQAMSENYAAMSLQVVEQDICRAIAHAVRFECQTYPRPYKVAMLMQAPYYFQEAQIEA
                     AIAAMDVAPEYADIRQVESSTAVLYLFSERFMTYGKAYGLCEWFEVEQFQNP"
     gene            19474..20142
                     /locus_tag="IRB70_000453"
     CDS             19474..20142
                     /locus_tag="IRB70_000453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416186.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBC0630410.1"
                     /translation="MSFTRRKFVLGMGTVIFFTGSASSLLANTRQEKKVRYAMIHDES
                     RCNGCNICARACRKTNHVPAQGSRLSIAHIPVTDNDNETQYHFFRQSCQHCEDAPCID
                     VCPTAASWRDEQGIVRVEKSQCIGCSYCIGACPYQVRYLNPVTKVADKCDFCAESRLA
                     KGFPPICVSACPEHALIFGREDSPEIQAWLQENKYYQYQLPGAGKPHLYRRLGQHLIK
                     KENV"
     gene            20139..20924
                     /locus_tag="IRB70_000454"
     CDS             20139..20924
                     /locus_tag="IRB70_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate reductase cytochrome B subunit"
                     /protein_id="HBC0630411.1"
                     /translation="MNPSQHAEQFQNQLANYVPQFTPQFWPVWLIIAGLLLVGMWLVL
                     GLHALLRARGVKKSATDHGEKVYLYSKAVRLWHWSNALLFVLLLASGLINHFALVGAT
                     AVKSLVAVHEVCGFLLLACWLGFVLINAVGGNGHHYRIRRQGWLERAAKQTRFYLFGI
                     MQGEEHPFPATTQSKFNPLQQVAYLGVMYGLLPLLLLTGLLCLYPQAVGDMFPGVRYW
                     LLQAHFALAFISLFFIFGHLYLCTTGRTPHETFKSMVDGYHRH"
     gene            20928..21740
                     /locus_tag="IRB70_000455"
     CDS             20928..21740
                     /locus_tag="IRB70_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630412.1"
                     /translation="MIITRADLREWRIGAVMYRWFLRHFPRGGSYADIHHALIEEGYT
                     DWAESLVEYAWKKWLADENFAHQEVSSMQKLATHPGERPFCSQFARSDDHARIGCCED
                     NARIATAGYAAQIASMGYSVRIGSVGFNSHIGSSGERARVAVTGNSSRISSAGDSSRI
                     ANTGMRVRVCTLGERCHVASNGDLVQIASFGANARIANSGDNVHIIASGENSTVVSTG
                     VVDSIILGPGGSAALAYHDGERVRFAVAIEGENNIRAGVRYRLNEQHQFVEC"
     gene            complement(21752..23356)
                     /locus_tag="IRB70_000456"
     CDS             complement(21752..23356)
                     /locus_tag="IRB70_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-NAD(P)-binding protein"
                     /protein_id="HBC0630413.1"
                     /translation="MKKIAIVGAGPTGIYTLFSLLQQQTPLSISIFEQADEAGVGMPY
                     SDEENSKLMLANIASIEIPPIYCTYLEWLQKQEASHLQRYGVKKETLHDRQFLPRILL
                     GEYFRDQFLRLVDQARQQKFAVAVYESCQVTDLQITNAGVMIATNQDLPSETFDLAVI
                     ATGHVWPDEEEATRTYFPSPWSGLMEAKVDACNVGIMGTSLSGLDAAMAVAIQHGSFI
                     EDDKQHVVFHRDNASEKLNITLMSRTGILPEADFYCPIPYEPLHTVTDQALNAEIQKG
                     EYGLLDRVFRLIVEEIKFADPGWSQRIALESLNVDSFAQAWFAERKQRAPFDWAEKNL
                     QEVERNKREKHTVPWRYVILRLHEAVQEIVPHLNEHDHKRFSKGLARVFIDNYAAIPS
                     ESIRRLLALREAGIIHILALGEDYEMEINESRTVLKTEDNSYSFDVFIDARGQRPLKV
                     KDIPFPGLREQLQKTGDEIPDVGEDYTLQQPEEIRGRVAFGALPWLMHDQPFVQGLTA
                     CAEIGEAMARAVVKPASRARKRLSFD"
     gene            complement(23482..23787)
                     /locus_tag="IRB70_000457"
     CDS             complement(23482..23787)
                     /locus_tag="IRB70_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monooxygenase"
                     /protein_id="HBC0630414.1"
                     /translation="MATLLQLHFSFNGPFGDAMAEQLKPLAESINQEPGFLWKVWTES
                     EKNHEAGGIYLFTDEKSALAYLEKHTARLKNLGVEEVVAKVFDVNEPLSQINQAKLA"
     gene            complement(23896..23972)
                     /locus_tag="IRB70_000458"
     tRNA            complement(23896..23972)
                     /locus_tag="IRB70_000458"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23936..23938),aa:Val,seq:gac)
     gene            complement(23977..24053)
                     /locus_tag="IRB70_000459"
     tRNA            complement(23977..24053)
                     /locus_tag="IRB70_000459"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(24017..24019),aa:Val,seq:gac)
     gene            24361..25617
                     /locus_tag="IRB70_000460"
     CDS             24361..25617
                     /locus_tag="IRB70_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA repeat-containing protein"
                     /protein_id="HBC0630415.1"
                     /translation="MGSDAKNLMSDGNVQIVKTGEVIGATQLTEGELIVEAGGRAENT
                     VVTGAGWLKVATGGIAKCTQYGNNGTLSVSDGAIATDIVQSEGGAISLSTLATVNGRH
                     PEGEFSVDKGYACGLLLENGGNLRVLEGHRAEKIILDQEGGLLVNGTTSAVVVDEGGE
                     LLVYPGGEASNCEINQGGVFMLAGKANDTLLAGGTMNNLGGEDSDTIVENGAIYRLGT
                     DGLQLYSSGKTQNLSVNVGGRAEVHAGTLENAVIQGGTVILLSPTSADENFVVEEDRA
                     PVELTGSVALLDGASMIIGYGADLQQSTITVQQGGVLILDGSTVKGDSVTFSVGNINL
                     NGGKLWLITGAATHVQLKVKRLRGEGAICLQTSAKEISPDFINVKGEVTGDIHVEITD
                     ASRQTLCNALKLQPDEDGIGATLQPA"
     gene            complement(25658..27031)
                     /gene="mdtK"
                     /locus_tag="IRB70_000461"
     CDS             complement(25658..27031)
                     /gene="mdtK"
                     /locus_tag="IRB70_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MATE transporter MdtK"
                     /protein_id="HBC0630416.1"
                     /translation="MQKYISEARLLLALAIPVILAQIAQTAMGFVDTVMAGGYSATDM
                     AAVAIGTSIWLPAILFGHGLLLALTPVIAQLNGSGRRERIAHQVRQGFWLAGFVSVLI
                     MLVLWNAGYIIRSMENIDPALADKAVGYLRALLWGAPGYLFFQVARNQCEGLAKTKPG
                     MVMGFIGLLVNIPVNYIFIYGHFGMPELGGVGCGVATAAVYWVMFLAMVSYIKRARSM
                     RDIRNEKGTAKPDPAVMKRLIQLGLPIALALFFEVTLFAVVALLVSPLGIVDVAGHQI
                     ALNFSSLMFVLPMSLAAAVTIRVGYRLGQGSTLDAQTAARTGLMVGVCMATLTAIFTV
                     SLREQIALLYNDNPEVVTLAAHLMLLAAVYQISDSIQVIGSGILRGYKDTRSIFYITF
                     TAYWVLGLPSGYILALTDLVVEPMGPAGFWIGFIIGLTSAAIMMMLRMRFLQRLPSAI
                     ILQRAAR"
     gene            27246..27887
                     /gene="ribE"
                     /locus_tag="IRB70_000462"
     CDS             27246..27887
                     /gene="ribE"
                     /locus_tag="IRB70_000462"
                     /EC_number="2.5.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin synthase"
                     /protein_id="HBC0630417.1"
                     /translation="MFTGIVQGTAKLVSIDEKPNFRTHVVELPDHMLDGLETGASVAH
                     NGCCLTVTEINGNHVSFDLMKETLRITNLGDLKVGDWVNVERAAKFSDEIGGHLMSGH
                     IMTTAEVAKILTSENNRQIWFKVQDSQLMKYILYKGFIGIDGISLTVGEVTPTRFCVH
                     LIPETLERTTLGKKKLGARVNIEIDPQTQAVVDTVERVLAARENAMNQPGTEA"
     gene            complement(27927..29075)
                     /gene="cfa"
                     /locus_tag="IRB70_000463"
     CDS             complement(27927..29075)
                     /gene="cfa"
                     /locus_tag="IRB70_000463"
                     /EC_number="2.1.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclopropane fatty acyl phospholipid synthase"
                     /protein_id="HBC0630418.1"
                     /translation="MSSSCIEEVSVPDDNWYRIANELLSRAGIAINGSAPADIRVKNP
                     DFFKRVLQEGSLGLGESYMDGWWECDRLDMFFSKVLRAGLENQLPHHFKDTLRIAGAR
                     LFNLQSKKRAWIVGKEHYDLGNDLFSRMLDPFMQYSCAYWKDADNLESAQQAKLKMIC
                     EKLQLKPGMRVLDIGCGWGGLAHYMASNYDVSVVGVTISAEQQKMAQERCEGLDVTIL
                     LQDYRDLNDQFDRIVSVGMFEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGSKKTDLN
                     VDPWINKYIFPNGCLPSVRQIAQSSEPHFVMEDWHNFGADYDTTLMAWYERFLAAWPE
                     IADNYSERFKRMFTYYLNACAGAFRARDIQLWQVVFSRGVENGLRVAR"
     gene            complement(29366..30577)
                     /locus_tag="IRB70_000464"
     CDS             complement(29366..30577)
                     /locus_tag="IRB70_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bcr/CflA family multidrug efflux MFS
                     transporter"
                     /protein_id="HBC0630419.1"
                     /translation="MQPGKRFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPASAVS
                     ASLSLFLAGFAAAQLLWGPLSDRYGRKPVLLIGLTIFALGSLGMLWVENAATLLVLRF
                     VQAVGVCAAAVIWQALVTDYYPSQKVNRIFATIMPLVGLSPALAPLLGSWLLVHFSWQ
                     AIFATLFAITVVLILPIFWLKPTTKARNNSQDGLTFTDLLRSKTYRGNVLIYAACSAS
                     FFAWLTGSPFILSEMGYSPAVIGLSYVPQTIAFLIGGYGCRAALQKWQGKQLLPWLLV
                     LFAVSVIATWAAGFISHVSLVEILIPFCVMAIANGAIYPIVVAQALRPFPHATGRAAA
                     LQNTLQLGLCFLASLVVSWLISISTPLLTTTSVMLSTVVLVALGYMMQRCEEVGCQNH
                     GNAEVAHSESH"
     gene            30690..31622
                     /locus_tag="IRB70_000465"
     CDS             30690..31622
                     /locus_tag="IRB70_000465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0630420.1"
                     /translation="MWSEYSLEVVDAVARNGSFSAAAQELHRVPSAVSYTVRQLEEWL
                     AVPLFERRHRDVELTAAGAWFLKEGRSVVKKMQITRQQCQQIANGWRGQLAIAVDNIV
                     RPERTRQMIVDFYRHFDDVELLVFQEVFNGVWDALSDGRVELAIGATRAIPVGGRYAF
                     RDMGMLSWSCVVASHHPLALMDGPFSDDTLRNWPSLVREDTSRTLPKRITWLLDNQKR
                     LVVPDWESSATCISAGLCIGMVPTHFAKPWLNEGKWVALELENPFPDSACCLTWQQND
                     MSPALTWLLEYLGDSETLNKEWLREPEETPATGD"
     gene            complement(31619..32644)
                     /gene="purR"
                     /locus_tag="IRB70_000466"
     CDS             complement(31619..32644)
                     /gene="purR"
                     /locus_tag="IRB70_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor PurR"
                     /protein_id="HBC0630421.1"
                     /translation="MATIKDVAKRANVSTTTVSHVINKTRFVAEETRNAVWAAIKELH
                     YSPSAVARSLKVNHTKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLE
                     KQRAYLSMMAQKRVDGLLVMCSEYPEPLLAMLEEYRHIPMVVMDWGEAKADFTDAVID
                     NAFEGGYMAGRYLIERGHREIGVIPGPLERNTGAGRLAGFMKAMEEAMIKVPESWIVQ
                     GDFEPESGYRAMQQILSQPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDN
                     VRNARYFTPALTTIHQPKDSLGETAFNMLLDRIVNKREEPQSIEVHPRLIERRSVADG
                     PFRDYRR"
     gene            32943..33032
                     /gene="ynhF"
                     /locus_tag="IRB70_000467"
     CDS             32943..33032
                     /gene="ynhF"
                     /locus_tag="IRB70_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein YnhF"
                     /protein_id="HBC0630422.1"
                     /translation="MSTDLKFSLVTTIIVLGLIVAVGLTAALH"
     gene            33198..34367
                     /locus_tag="IRB70_000468"
     CDS             33198..34367
                     /locus_tag="IRB70_000468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630423.1"
                     /translation="MKINYPLLALAIGAFGIGTTEFSPMGLLPVIARGVDVSIPAAGM
                     LISAYAVGVMVGAPLMTLLLSHRARRSALIFLMAIFTLGNVLSAIAPNYMTLMLSRIL
                     TSLNHGAFFGLGSVVAASVVPKHKQASAVATMFMGLTLANIGGVPAATWLGETIGWRM
                     SFLATAGLGVISMVSLFFSLPKGGAGARPEVKKELAVLMRPQVLSALLTTVLGAGAMF
                     TLYTYISPVLQSITHATPVFVTAMLVLIGVGFSIGNYLGGKLADRSVNGTLKGFLLLL
                     MVIMLAIPFLARNEFGAAISMVVWGAATFAVVPPLQMRVMRVASEAPGLSSSVNIGAF
                     NLGNALGAAAGGAVISAGLGYSFVPVMGAIVAGLALLLVFMSARKQPETVCVANS"
     gene            complement(34513..35094)
                     /gene="sodB"
                     /locus_tag="IRB70_000469"
     CDS             complement(34513..35094)
                     /gene="sodB"
                     /locus_tag="IRB70_000469"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Fe]"
                     /protein_id="HBC0630424.1"
                     /translation="MSFELPALPYAKDALAPHISAETIEYHYGKHHQTYVTNLNNLIK
                     GTAFEGKSLEEIIRSSEGGVFNNAAQVWNHTFYWNCLAPNAGGEPTGKVAEAIAASFG
                     SFADFKAQFTDAAIKNFGSGWTWLVKNSDGKLAIVSTSNAGTPLTTDATPLLTVDVWE
                     HAYYIDYRNARPGYLEHFWALVNWEFVAKNLAA"
     gene            complement(35222..36049)
                     /gene="mepH"
                     /locus_tag="IRB70_000470"
     CDS             complement(35222..36049)
                     /gene="mepH"
                     /locus_tag="IRB70_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-endopeptidase MepH"
                     /protein_id="HBC0630425.1"
                     /translation="MARINRISITLCALLFTTLPLTPMAHASKQARESSATTHITKKA
                     DKKKSTATTKKTQKASQKTAKKAASKSTIKSKTASSVKKSSITASKNAKTRSKHAVNK
                     TASANFTEKCTKRKGYKSHCVKVKNAASGTLADAHKAKVQKATKVAMNKLMQQIGKPY
                     RWGGSSPRTGFDCSGLVYYAYKDLVKIRIPRTANEMYHLRDAAPIERSELKNGDLVFF
                     RTQGRGTADHVGVYVGNGKFIQSPRTGQEIQITSLSEDYWQRHYVGARRVMTPKTLR"
     gene            36384..36731
                     /gene="grxD"
                     /locus_tag="IRB70_000471"
     CDS             36384..36731
                     /gene="grxD"
                     /locus_tag="IRB70_000471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monothiol glutaredoxin 4"
                     /protein_id="HBC0630426.1"
                     /translation="MSTTIEKIQRQIAENPILLYMKGSPKLPSCGFSAQAVQALAACG
                     ERFAYVDILQNPDIRAELPKYANWPTFPQLWVDGELVGGCDIVIEMYQRGELQQLIKE
                     TAAKYKSEEPDAE"
     gene            complement(36782..41398)
                     /locus_tag="IRB70_000472"
     CDS             complement(36782..41398)
                     /locus_tag="IRB70_000472"
                     /EC_number="3.6.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBC0630427.1"
                     /translation="MADNLNPSSPLPDVFSPATRDWFLRAFKQPTAVQSQTWHVAARG
                     EHALVIAPTGSGKTLAAFLYALDQLFREGGEDTREAHKRKTSRILYISPIKALGTDVQ
                     RNLQIPLQGIADERRRRGETEVNLRVAIRTGDTPAQERSKLTRNPPDILITTPESLYL
                     MLTSRARETLRGVETVIIDEVHAVAGSKRGAHLALSLERLDALLHTSAQRIGLSATVR
                     SASDVAAFLGGDRPVTVVNPPAMRHPQIRIVVPVANMDDVSSVASGTGEDSHAGREGS
                     IWPYIETGILDEVLRHRSTIIFTNSRGLAEKLTARLNELYAARLQRSPSIAVDAAHFE
                     STSGATSNRVQSSDIFIARSHHGSVSKEQRAITEQALKSGELRCVVATSSLELGIDMG
                     AVDLVIQVATPLSVASGLQRIGRAGHQVGGVSKGLFFPRTRRDLVDSAVIVECMFAGR
                     LENLTPPHNPLDVLAQQTVAAAAMDALQVDEWYSRVRRAAPWKDLPGRVFDATLDMLS
                     GRYPSGDFSAFRPKLVWNRETGILTARPGAQLLAVTSGGTIPDRGMYSVLLPEGEEQA
                     GSRRVGELDEEMVYESRVNDIITLGATSWRIQQITRDQVIVTPAPGRSARLPFWRGEG
                     NGRPAELGEMIGDFLHLLADGAFFSGTIPPWLAEENTIANIQGLIDEQRNATGIVPGS
                     RHLVLERCRDEIGDWRIILHSPYGRRVHEPWALAIAGRIHALWGADASVVASDDGIVA
                     RIPDTDGKLPDAAIFLFEPEKLLQIVREAVGSSALFAARFRECAARALLMPGRTPGHR
                     TPLWQQRLRASQLLEIAQGYPDFPVILETLRECLQDVYDLPALERLMRRLNGGEIQIS
                     DVTTTTPSPFAASLLFGYVAEFMYQSDAPLAERRASVLSLDSELLRNLLGQVEPGELL
                     DPQVIRQVEEELQRLAPGRRAKGEEGLFDLLRELGPMTVEDLAQRHTGSSEEIASYLE
                     NLLAVKRIFPTMISGQERLACMDDAARLRDALGVRLPESLPEIYLHRVSYPLRDLFLR
                     YLRAHALVTAEQLAHEFSLGIAIVEEQLQQLREQGLVMNLQQDIWVSDEVFRRLRLRS
                     LQAAREATRPVAATTYARLLLERQGVLPATDGSPALFASTSPGVYEGVDGVMRVIEQL
                     AGVGLPASLWESQILPARVRDYSPEMLDELLATGAVIWSGQKKLGEDDGLVALHLQEY
                     AAESFTPAEADQANRSALQQAIVAVLADGGAWFAQQISQRIRDKIGESVDPSALQEAL
                     WALVWQGVITSDIWAPLRALTRSSSNARTSTRRSHRARRGRPVYAQPVSPRVSYNTPK
                     LAGRWSLLQVEPLNDTERMLALAENMLDRYGIISRQAVIAENIPGGFPSMQTLCRSME
                     DSGRIMRGRFVEGLGGAQFAERLTIDRLRDLATQTAQTRHYTPVALSANDPANVWGNL
                     LPWPAHPATLVPTRRAGALVVVSGGKLLLYLAQGGKKMLVWQEKEELLAPEVFHALTT
                     ALRREPRLRFTLTEVNDLPVRQTPMFTLLREAGFSSSPQGLDWG"
     gene            complement(41491..42138)
                     /gene="rnt"
                     /locus_tag="IRB70_000473"
     CDS             complement(41491..42138)
                     /gene="rnt"
                     /locus_tag="IRB70_000473"
                     /EC_number="3.1.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease T"
                     /protein_id="HBC0630428.1"
                     /translation="MSDNAQLTGLCDRFRGFYPVVIDVETAGFNAKTDALLEIAAITL
                     KMDEQGWLMPDTTLHFHVEPFVGANLQPEALAFNGIDPNDPDRGAVSEYEALHEIFKV
                     VRKGIKASGCNRAIMVAHNANFDHSFMMAAAERASLKRNPFHPFATFDTAALAGLALG
                     QTVLSKACQTAGMDFDSTQAHSALYDTERTAVLFCEIVNRWKRLGGWPLPAAEEV"
     gene            complement(42241..42648)
                     /gene="gloA"
                     /locus_tag="IRB70_000474"
     CDS             complement(42241..42648)
                     /gene="gloA"
                     /locus_tag="IRB70_000474"
                     /EC_number="4.4.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008500591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBC0630429.1"
                     /translation="MRLLHTMLRVGDLQRSIDFYTKVLGMKLLRTSENPEYKYSLAFV
                     GYGPETEEAVIELTYNWGVDKYELGTAYGHIALSVDNAAEACEKIRQNGGNVTREAGP
                     VKGGTTVIAFVEDPDGYKIELIEEKDAGRGLGN"
     gene            complement(42729..43826)
                     /gene="nemA"
                     /locus_tag="IRB70_000475"
     CDS             complement(42729..43826)
                     /gene="nemA"
                     /locus_tag="IRB70_000475"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-ethylmaleimide reductase"
                     /protein_id="HBC0630430.1"
                     /translation="MSSEKLYSPLKVGAITAANRIFMAPLTRLRSIEPGDIPTPLMAE
                     YYRQRASAGLIISEATQISAQAKGYAGAPGIHSPEQIAAWKKITAGVHAENGHMAVQL
                     WHTGRISHASLQPGGQAPVAPSALSAGTRTSLRDENGQAIRVETSMPRALELEEIPGI
                     VNDFRQAISNAREAGFDLVELHSAHGYLLHQFLSPSSNHRTDQYGGSVENRARLVLEV
                     VDAGIEEWGADRIGIRVSPIGTFQNTDNGPNEEADALYLIEQLGKRGIAYLHMSEPDW
                     AGGEPYTDAFREKVRARFHGPIIGAGAYTVEKAETLIGKGLIDAVAFGRDWIANPDLV
                     ARLQRKAELNPQRAESFYGGGAEGYTDYPTL"
     gene            complement(43863..44462)
                     /gene="nemR"
                     /locus_tag="IRB70_000476"
     CDS             complement(43863..44462)
                     /gene="nemR"
                     /locus_tag="IRB70_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310384.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NemR"
                     /protein_id="HBC0630431.1"
                     /translation="MNKHTEHDTREHLLATGEQLCLQRGFTGMGLSELLKTAEVPKGS
                     FYHYFRSKEAFGVAMLERHYAAYHQRLTELLQSGEGNYRDRILAYYQQTLNQFCQHGT
                     ISGCLTVKLSAEVCDLSEDMRSAMDKGARGVIALLSQALENGRDSHCLTFCGEPLQQA
                     QVLYALWLGANLQAKISRNSEPLENALAHVKTIIATPAV"
     gene            44565..44804
                     /locus_tag="IRB70_000477"
     CDS             44565..44804
                     /locus_tag="IRB70_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1289 domain-containing protein"
                     /protein_id="HBC0630432.1"
                     /translation="MAEQLEFFPVQSPCRGICQSDERGFCRGCFRSRDERFNWNKMSD
                     GEKQEVLRLCRQRLMRKLRANKPASSDEPEQPSLF"
     gene            44853..45749
                     /locus_tag="IRB70_000478"
     CDS             44853..45749
                     /locus_tag="IRB70_000478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase family oxidoreductase"
                     /protein_id="HBC0630433.1"
                     /translation="MVQRITIAPQGPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDL
                     GVTTVDHADIYGGYQCEAAFGEALKLAPHLRERMEIVSKCGIATTAREENVIGHYITD
                     RDHIIKSAEQSLINLATDHLDLLLIHRPDPLMDADEVADAFKHLHQSGKVRHFGVSNF
                     TPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGGRLF
                     NDDYFQPLRDELAVVAEELNAGSIEQVVYAWVLRLPSQPLPIIGSGKIERVRAAVEAE
                     TLKMTRQQWFRIRKAALGYDVP"
     gene            45830..46351
                     /gene="sodC"
                     /locus_tag="IRB70_000479"
     CDS             45830..46351
                     /gene="sodC"
                     /locus_tag="IRB70_000479"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Cu-Zn] SodC2"
                     /protein_id="HBC0630434.1"
                     /translation="MKRFSLAILALVVATGAQAASEKVEMNLVTSQGVGQSIGSVTIT
                     ETDKGLEFSPDLKALPPGEHGFHIHAKGSCQPATKDGKASAAESAGGHLDPQNTGKHE
                     GPEGAGHLGDLPALVVNNDGKATDAVIAPRLKSLDEVKDKALMVHVGGDNMSDQPKPL
                     GGGGERYACGVIK"
     gene            complement(46352..48364)
                     /locus_tag="IRB70_000480"
     CDS             complement(46352..48364)
                     /locus_tag="IRB70_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBC0630435.1"
                     /translation="MNASSWSLRNLPWFRATLAQWRYALRNTIAMCLALTVAYYLNLD
                     EPYWAMTSAAVVSFPTVGGVISKSLGRIAGSLLGAIAALLLAGHTLNEPCFFLLSMAA
                     WLGFCTWACAHFTNNVAYAFQLAGYTAAIIAFPMVNITEASQLWDIAQARVCEVIVGI
                     LCGGMMMMILPSSSDATALLTALKNMHARLLEHASLLWQPETTDAIRAAHEGVIGQIL
                     TMNLLRIQAFWSHYRFRQQNARLNALLHQQLRMTSVISSLRRMLLNWPSPPGATREIL
                     EQLLTALASSQTDVYTVARIIAPLRPTNVADYRHVAFWQRLRYFCRLYLQSSQELHHL
                     QSGVDDHTRLPRTSGLARHTDNAEAMWSGLRTFCTLMMIGAWSIASQWDAGANALTLA
                     AISCVLYSAVAAPFKSLSLLMRTLVLLSLFSFVVKFGLMVQISDLWQFLLFLFPLLAT
                     MQLLKLQMPKFAALWGQLIVFMGSFIAVTNPPVYDFADFLNDNLAKIVGVALAWLAFA
                     ILRPGSDARKSRRHIRALRRDFVDQLSRHPSLSESEFESLTYHHVSQLSNSQDAMARR
                     WLLRWGVVLLNCSHVVWQLRDWESRSDPLSRVRDNCISLLRGVMSERGVQQKSLAATL
                     EELQRICDSLARHHQPAARELAAIVWRLYCSLSQLEQAPPQGTLAS"
     gene            complement(48364..49221)
                     /locus_tag="IRB70_000481"
     CDS             complement(48364..49221)
                     /locus_tag="IRB70_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416161.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBC0630436.1"
                     /translation="MSIKTIKYFSTIIVAVVAVLAGWWLWNYYMQSPWTRDGKIRAEQ
                     VSITPQVSGRIVELNIKDNQLVNAGDLLLTIDKTPFQIAELNAQAQLAKAQSDLAKAN
                     NEANRRRHLSQNFISAEELDTANLNVKAMQASVDAAQATLKQAQWQLAQTEIRAPVSG
                     WVTNLTTRIGDYADTGKPLFALVDSHSFYVIGYFEETKLRHIREGAPAQITLYSDNKT
                     LQGHVSSIGRAIYDQSVESDSSLIPDVKPNVPWVRLAQRVPVRFALDKVPGDVTLVSG
                     TTCSIAVGQ"
     gene            complement(49224..49460)
                     /locus_tag="IRB70_000482"
     CDS             complement(49224..49460)
                     /locus_tag="IRB70_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1656 domain-containing protein"
                     /protein_id="HBC0630437.1"
                     /translation="MKFMLNATGLPLQDLVFGASVYFPPFFKAFAFGFVIWLVVHRLL
                     RGWIYAGDIWHPLLMDLSLFAICVCLALAILIAW"
     gene            49661..50095
                     /gene="slyA"
                     /locus_tag="IRB70_000483"
     CDS             49661..50095
                     /gene="slyA"
                     /locus_tag="IRB70_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416159.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SlyA"
                     /protein_id="HBC0630438.1"
                     /translation="MESPLGSDLARLVRIWRALIDHRLKPLELTQTHWVTLHNIHQLP
                     PDQSQIQLAKAIGIEQPSLVRTLDQLEEKGLISRQTCASDRRAKRIKLTEKAEPLISE
                     MEAVINKTRAEILHGISAEELEQLIKLIAKLEHNIIELQAKG"
     gene            complement(50142..50609)
                     /gene="slyB"
                     /locus_tag="IRB70_000484"
     CDS             complement(50142..50609)
                     /gene="slyB"
                     /locus_tag="IRB70_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein SlyB"
                     /protein_id="HBC0630439.1"
                     /translation="MIKRVLVVSMVGLSLVGCVNNDTLSGDVYTASEAKQVQNVSYGT
                     IVNVRPVQIQGGDDSNVIGAIGGAVLGGFLGNTVGGGTGRSLATAAGAVAGGVAGQGV
                     QSAMNKTQGVELEIRKDDGNTIMVVQKQGNTRFSPGQRVVLASNGSQVTVSPR"
     gene            50883..51992
                     /gene="anmK"
                     /locus_tag="IRB70_000485"
     CDS             50883..51992
                     /gene="anmK"
                     /locus_tag="IRB70_000485"
                     /EC_number="2.7.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anhydro-N-acetylmuramic acid kinase"
                     /protein_id="HBC0630440.1"
                     /translation="MKSGRFIGVMSGTSLDGVDVVLATIDEHRVAQLASLSWPIPVSL
                     KQAVLDICQGQQLTLSQFGQLDTQLGRLFADAVNALLKEQNLQARDIVAIGCHGQTVW
                     HEPTGVAPHTLQIGDNNQIVARTGITVVGDFRRRDIALGGQGAPLVPAFHHALLAHPT
                     ERRMVLNIGGIANLSLLIPGQPVGGYDTGPGNMLMDAWIWRQAGKPYDKDAEWARAGK
                     VILPLLQNMLSDPYFSQPAPKSTGREYFNYGWLERHLRHFPGVDPRDVQATLAELTAV
                     TISEQVLLSGGCERLMVCGGGSRNPLLMARLAALLPGTEVTTTDAVGISGDDMEALAF
                     AWLAWRTLAGLPGNLPSVTGASQETVLGAIFPANL"
     gene            52090..52419
                     /gene="mliC"
                     /locus_tag="IRB70_000486"
     CDS             52090..52419
                     /gene="mliC"
                     /locus_tag="IRB70_000486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416156.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C-type lysozyme inhibitor"
                     /protein_id="HBC0630441.1"
                     /translation="MSMKKLLLICLPVLLTGCSAFNQLVERMQTDTLEYQCDEKPLTV
                     KLNNPRQEVSFVYDNQLLHLKQGISASGARYTDGIYVFWSKGEEATVYKRDRIVLNNC
                     QLQNPQR"
     gene            52478..53134
                     /gene="pdxH"
                     /locus_tag="IRB70_000487"
     CDS             52478..53134
                     /gene="pdxH"
                     /locus_tag="IRB70_000487"
                     /EC_number="1.4.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxamine 5'-phosphate oxidase"
                     /protein_id="HBC0630442.1"
                     /translation="MSDNDELQQIAHLRREYTKGGLRRRDLPADPLTLFERWLSQACD
                     AKLADPTAMVVATVDEHGQPYQRIVLLKHYDEKGMVFYTNLGSRKAHQIENNPRVSLL
                     FPWHTLERQVMVIGKAERLSTLEVMKYFHSRPRDSQIGAWVSKQSSRISARGILESKF
                     LELKQKFQQGEVPLPSFWGGFRVSLEQIEFWQGGEHRLHDRFLYQRENDAWKIDRLAP
                     "
     gene            53263..54537
                     /gene="tyrS"
                     /locus_tag="IRB70_000488"
     CDS             53263..54537
                     /gene="tyrS"
                     /locus_tag="IRB70_000488"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBC0630443.1"
                     /translation="MASSNLIKQLQERGLVAQVTDEEALAERLAQGPIALYCGFDPTA
                     DSLHLGHLVPLLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVD
                     KIRKQVAPFLDFDCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQR
                     LNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQN
                     QVFGLTVPLITKADGTKFGKTEGGAVWLDPKKTSPYKFYQFWINTADADVYRFLKFFT
                     FMSIEEINALEEEDKNSGKAPRAQYVLAEQVTRLVHGEEGLQAAKRITECLFSGSLSA
                     LSEADFEQLAQDGVPMVEMEKGADLMQALVDSELQPSRGQARKTIASNAITINGEKQS
                     DPEYFFKEEDRLFGRFTLLRRGKKNYCLICWK"
     gene            54598..55458
                     /gene="pdxY"
                     /locus_tag="IRB70_000489"
     CDS             54598..55458
                     /gene="pdxY"
                     /locus_tag="IRB70_000489"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310372.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal kinase PdxY"
                     /protein_id="HBC0630444.1"
                     /translation="MKNILAIQSHVVYGHAGNSAAEFPMRRLGANVWPLNTVQFSNHT
                     QYGKWTGCVMPPSHLTEIVQGIAAIDKLHTCDAVLSGYLGSAEQGEHILGIVRQVKAA
                     NPQAKYFCDPVMGHPEKGCIVAPGVAEFHVRHGLPASDIIAPNLVELEILCEHPVNNV
                     EEAVLAARELIAQGPQIVLVKHLARAGYSRDRFEMLLVTADEAWHISRPLVDFGMRQP
                     VGVGDVTSGLLLVKLLQGATLQEALEHVTAAVYEIMVTTKAMQEYELQVVAAQDRIAK
                     PEHYFSATKL"
     gene            complement(55502..56107)
                     /gene="gstA"
                     /locus_tag="IRB70_000490"
     CDS             complement(55502..56107)
                     /gene="gstA"
                     /locus_tag="IRB70_000490"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase GstA"
                     /protein_id="HBC0630445.1"
                     /translation="MKLFYKPGACSLASHITLRESGKDFTLVSVDLMKKRLENGDDYF
                     AVNPKGQVPALLLDDGTLLTEGVAIMQYLADSVPDRQLLAPVNSISRYKTIEWLNYIA
                     TELHKGFTPLFRPDTPEEYKPTVRAQLEKKLQYVNDALKDEHWICGQRFTIADAYLFT
                     VLRWAYAVKLNLEGLEHIAAFMQRMAERPEVQDALSAEGLK"
     gene            complement(56213..57715)
                     /gene="dtpA"
                     /locus_tag="IRB70_000491"
     CDS             complement(56213..57715)
                     /gene="dtpA"
                     /locus_tag="IRB70_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpA"
                     /protein_id="HBC0630446.1"
                     /translation="MSTANQKPTESVSLNAFKQPKAFYLIFSIELWERFGYYGLQGIM
                     AVYLVKQLGMSEADSITLFSSFSALVYGLVAIGGWLGDKVLGTKRVIMLGAIVLAIGY
                     ALVAWSGHDAGIVYMGMAAIAVGNGLFKANPSSLLSTCYEKNDPRLDGAFTMYYMSVN
                     IGSFFSMIATPWLAAKYGWSVAFALSVVGLLITIVNFAFCQRWVKQYGSKPDFEPINY
                     RNLLLTIIGVVALIAIATWLLHNQEVARMALGVVAFGIVVIFGKEAFAMKGAARRKMI
                     VAFILMLEAIIFFVLYSQMPTSLNFFAIRNVEHTILGLAVEPEQYQALNPFWIIIGSP
                     ILAAIYNKMGDTLPMPTKFAIGMVMCSGAFLILPLGAKFASDAGIVSVSWLVASYGLQ
                     SIGELMISGLGLAMVAQLVPQRLMGFIMGSWFLTTAGANLIGGYVAGMMAVPDNVTDP
                     LMSLEVYGRVFLQIGVATAVIAVLMLLTAPKLHRMTQDDAADKAAKAAVA"
     gene            complement(58326..58961)
                     /gene="nth"
                     /locus_tag="IRB70_000492"
     CDS             complement(58326..58961)
                     /gene="nth"
                     /locus_tag="IRB70_000492"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBC0630447.1"
                     /translation="MNKAKRLEILTRLRENNPHPTTELNFSSPFELLIAVLLSAQATD
                     VSVNKATAKLYPVANTPAAMLELGVEGVKTYIKTIGLYNSKAENIIKTCRILLEQHNG
                     EVPEDRAALEALPGVGRKTANVVLNTAFGWPTIAVDTHIFRVCNRTQFAPGKNVEQVE
                     EKLLKVVPAEFKVDCHHWLILHGRYTCIARKPRCGSCIIEDLCEYKEKVDI"
     gene            complement(58961..59656)
                     /gene="rsxE"
                     /locus_tag="IRB70_000493"
     CDS             complement(58961..59656)
                     /gene="rsxE"
                     /locus_tag="IRB70_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxE"
                     /protein_id="HBC0630448.1"
                     /translation="MSEIKDVIVQGLWKNNSALVQLLGLCPLLAVTSTATNALGLGLA
                     TTLVLTLTNLTISTLRHWTPAEIRIPIYVMIIASVVSAVQMLINAYALGLYQSLGIFI
                     PLIVTNCIVVGRAEAFAAKKGPALSALDGFSIGMGATCAMFVLGSLREIIGNGTLFDG
                     ADALLGSWAKVLRVEIFHTDSPFLLAMLPPGAFIGLGLMLAGKYLIDEKMKKRRTEAA
                     AERALPNGETGNV"
     gene            complement(59660..60280)
                     /gene="rsxG"
                     /locus_tag="IRB70_000494"
     CDS             complement(59660..60280)
                     /gene="rsxG"
                     /locus_tag="IRB70_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxG"
                     /protein_id="HBC0630449.1"
                     /translation="MLKTIRKHGITLALFAAGSTGLTAAINQMTKTTIAEQASLQQKA
                     LFDQVLPAERYNNALAQSCYLVTAPELGKGEHRVYIAKQDDKPVAAVLETTAPDGYSG
                     AIQLLVGADFNGTVLGTRVTEHHETPGLGDKIELRLSDWITHFAGKKISGADDAHWAV
                     KKDGGDFDQFTGATITPRAVVNAVKRAGLYAQTLPSQLSQLPACGE"
     gene            complement(60284..61342)
                     /gene="rsxD"
                     /locus_tag="IRB70_000495"
     CDS             complement(60284..61342)
                     /gene="rsxD"
                     /locus_tag="IRB70_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxD"
                     /protein_id="HBC0630450.1"
                     /translation="MVFRIASSPYTHNQRQTSRIMLLVLLAAVPGIAAQLWFFGWGTL
                     VQILLASVSALLAEALVLKLRKQSVAATLKDNSALLTGLLLAVSIPPLAPWWMVVLGT
                     VFAVIIAKQLYGGLGQNPFNPAMIGYVVLLISFPVQMTSWLPPHEIAVNIPGFIDAIQ
                     VIFSGHTASGGDMNTLRLGIDGISQATPLDTFKTSVRAGHSVEQIMQYPIYSGMLAGA
                     GWQWVNLAWLAGGVWLLWQKAIRWHIPLSFLVTLALCATLGWLFSPDTLAAPQIHLLS
                     GATMLGAFFILTDPVTASTTNRGRLIFGALAGLLVWLIRSFGGYPDGVAFAVLLANIT
                     VPLIDYYTRPRVYGHRKG"
     gene            complement(61343..63565)
                     /gene="rsxC"
                     /locus_tag="IRB70_000496"
     CDS             complement(61343..63565)
                     /gene="rsxC"
                     /locus_tag="IRB70_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxC"
                     /protein_id="HBC0630451.1"
                     /translation="MLKLFSAFRKNKIWDFNGGIHPPEMKTQSNGTPLRQVPLAQRFV
                     IPLKQHIGAEGELCVSVGDKVLRGQPLTRGRGKMLPVHAPTSGTVTAIAPHSTAHPSA
                     LAELSVIIDADGEDCWIPRDGWDDYRSRSREELIERIHQFGVAGLGGAGFPTGVKLQG
                     GGDKIETLIINAAECEPYITADDRLMQDCAAQVVEGIRILAHILQPREILIGIEDNKP
                     QAISMLRAVLADSHDISLRVIPTKYPSGGAKQLTYILTGKQVPHGGRSSDIGVLMQNV
                     GTAYAVKRAVIDGEPITERVVTLTGEAIARPGNVWARLGTPVRHLLNDAGFCPSADQM
                     VIMGGPLMGFTLPWLDVPVVKITNCLLAPSANELGEPQEEQSCIRCSACADACPADLL
                     PQQLYWFSKGQQHDKATTHNIADCIECGACAWVCPSNIPLVQYFRQEKAEIAAIRQEE
                     KRAAEAKARFEARQARLEREKAARLERHKSAAVQPAAKDKDAIAAALARVKEKQAQAT
                     QPIVIKAGERPDNSAIIAAREARKAQARAKQAELQQTNDAATVADPRKTAVEAAIARA
                     KARKLEQQQANAEPEEQVDPRKAAIEAAIARAKARKLEQQQANAEPEQQVDPRKAAVE
                     AAIARAKARKLEQQQANAEPEQQVDPRKAAVEAAIARAKARKLEQQQANAEPEEQVDP
                     RKAAVEAAIARAKARKLEQQQANAEPEEQIDPRKAAVAAAIARVQAKKAAQQKVVNED
                     "
     gene            complement(63558..64136)
                     /gene="rsxB"
                     /locus_tag="IRB70_000497"
     CDS             complement(63558..64136)
                     /gene="rsxB"
                     /locus_tag="IRB70_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxB"
                     /protein_id="HBC0630452.1"
                     /translation="MNAIWIAVAAVSLLGLAFGAILGYASRRFAVEDDPVVEKIDEIL
                     PQSQCGQCGYPGCRPYAEAISCNGEKINRCAPGGEAVMLKIAELLNVEPQPLDGEAQE
                     LTPAQMVAVIDENNCIGCTKCIQACPVDAIVGATRAMHTVMSDLCTGCNLCVDPCPTH
                     CISLQPVAETPDSWKWDLNTIPVRIIPVEHHA"
     gene            complement(64136..64717)
                     /gene="rsxA"
                     /locus_tag="IRB70_000498"
     CDS             complement(64136..64717)
                     /gene="rsxA"
                     /locus_tag="IRB70_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017456621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport complex subunit RsxA"
                     /protein_id="HBC0630453.1"
                     /translation="MTDYLLLFVGTVLVNNFVLVKFLGLCPFMGVSKKLETAMGMGLA
                     TTFVMTLASICAWLIDTWILIPLNLIYLRTLAFILVIAVVVQFTEMVVRKTSPVLYRL
                     LGIFLPLITTNCAVLGVALLNINLGHNFLQSALYGFSAAVGFSLVMVLFAAIRERLAV
                     ADVPAPFRGNAIALITAGLMSLAFMGFSGLVKL"
     gene            complement(64794..65234)
                     /locus_tag="IRB70_000499"
     CDS             complement(64794..65234)
                     /locus_tag="IRB70_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707526.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2569 domain-containing protein"
                     /protein_id="HBC0630454.1"
                     /translation="MTTTTPQRIGGWLLGPLAWLLVALLSTTLALLLYTAALSSPQTF
                     QTLGGQALTTQILWGVSFITAIAMWYYTLWLTIAFFKRRRCVPKHYIIWLLISVLLAV
                     KAFAFSPVEDGIAVRQLLFTLLATALIVPYFKRSSRVKATFVNP"
     gene            complement(65320..65535)
                     /gene="ydgT"
                     /locus_tag="IRB70_000500"
     CDS             complement(65320..65535)
                     /gene="ydgT"
                     /locus_tag="IRB70_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription modulator YdgT"
                     /protein_id="HBC0630455.1"
                     /translation="MTVQDYLLKFRKISSLESLEKLYDHLNYTLTDDQELINMYRAAD
                     HRRAELVSGGRLFDLGQVPKSVWHYVQ"
     gene            complement(65808..65933)
                     /gene="blr"
                     /locus_tag="IRB70_000501"
     CDS             complement(65808..65933)
                     /gene="blr"
                     /locus_tag="IRB70_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division septum protein Blr"
                     /protein_id="HBC0630456.1"
                     /translation="MNRLIELTGWIVLVVSVILLGVASHIDNYQPPEQSTTVQHK"
     gene            66176..67216
                     /locus_tag="IRB70_000502"
     CDS             66176..67216
                     /locus_tag="IRB70_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310359.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBC0630457.1"
                     /translation="MSDNIRVGLIGYGYASKTFHAPLIAGTPGLELAVISSSDETKVK
                     ADWPTVAVVSEPKHLFNDPNIDLIVIPTPNDTHFPLAKAALEAGKHVVVDKPFTVTLS
                     QARELEALAKSLGRVLSVFHNRRWDSDFLTLKGLLAEGVLGEVAYFESHFDRFHPQVR
                     DRWREQGGPGSGIWYDLAPHLLDQAITLFGLPVSMTVDLAQLRPGAQSTDYFHAILSY
                     PQRRVILHGTMLAAAESARYIVHGSRGSYVKYGLDPQEERLKNGERLPQEDWGYDMRD
                     GVLTRVEGEERVEETLLTVPGNYPAYYAAIRDALNGDGENPVPASQAIQVMELIELGI
                     ESAKHRATLCLA"
     gene            complement(67252..68253)
                     /gene="add"
                     /locus_tag="IRB70_000503"
     CDS             complement(67252..68253)
                     /gene="add"
                     /locus_tag="IRB70_000503"
                     /EC_number="3.5.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBC0630458.1"
                     /translation="MIDTTLPLTDIHRHLDGNIRPQTILELGRQYNISIPAQSLETLI
                     PHVQVIANEPDLVSFLTKLDWGVKVLASLDACRRVAFENIEDAARNGLHYVELRFSPG
                     YMAMAHQLPVAGVVEAVIDGVREGCRTFGVQAKLIGIMSRTFGEAACQQELEAFLAHR
                     DQITALDLAGDELGFPGSLFLSHFNRARDAGWHITVHAGEAAGPESIWQAIRELGAER
                     IGHGVKAIEDRALMDFLAEQQIGIESCLTSNIQTSTVAELAAHPLKMFLEHGIRASIN
                     TDDPGVQGVDIIHEYTVAAPAAGLSREQIRQAQINGLEMAFLSAEEKRALREKVAAK"
     gene            complement(68357..69529)
                     /gene="malY"
                     /locus_tag="IRB70_000504"
     CDS             complement(68357..69529)
                     /gene="malY"
                     /locus_tag="IRB70_000504"
                     /EC_number="4.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional maltose regulon transcriptional
                     repressor/cystathionine beta-lyase MalY"
                     /protein_id="HBC0630459.1"
                     /translation="MFDFSKVVDRHGTWCTQWDYVADRFGTADLLPFTISDMDFATAP
                     CIIEALNQRLMHGVFGYSRWKNDEFLAAIAHWFSTQHYTAIDPQSVVYGPSVIYMVSE
                     LIRQWSETGEGVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLAK
                     PECKIMLLCSPQNPTGKVWTCDELEIMADLCERHGVRVISDEIHMDMVWGEQPHIPWC
                     NVARGDWALLTSGSKSFNIPALTGAYGIIENSSSRDAYLSALKGRDGLSSPSVLALTA
                     HIAAYQQGAPWLDALRVYLKDNLTYIADKMNAAFPELNWQIPQSTYLAWLDLRPLNID
                     DNALQKALIEQEKVAIMPGYTYGEEGRGFVRLNAGCPRSKLEKGVAGLINAIRAVR"
     gene            complement(69539..71131)
                     /gene="malX"
                     /locus_tag="IRB70_000505"
     CDS             complement(69539..71131)
                     /gene="malX"
                     /locus_tag="IRB70_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS maltose transporter subunit IICB"
                     /protein_id="HBC0630460.1"
                     /translation="MTAKTAPKVTLWEFFQQLGKTFMLPVALLSFCGIMLGIGSSLSS
                     HDVITLIPVLGNPVLQAIFTWMSKIGSFAFSFLPVMFCIAIPLGLARENKGVAAFAGF
                     VGYAVMNLAVNFWLTNKGILPTTDAAVLKANNIQSILGIQSIDTGILGAVIAGIIVWM
                     LHERFHNIRLPDALAFFGGTRFVPIISSLVMGLVGLVIPLVWPIFAMGISGLGHMINS
                     AGDFGPMLFGTGERLLLPFGLHHILVALIRFTDAGGTQEVCGQTVSGALTIFQAQLSC
                     PTTHGFSESATRFLSQGKMPAFLGGLPGAALAMYHCARPENRHKIKGLLISGLIACVV
                     GGTTEPLEFLFLFVAPVLYVIHALLTGLGFTVMSVLGVTIGNTDGNIIDFVVFGILHG
                     LSTKWYMVPVVAAIWFVVYYVIFRFAITRFNLKTPGRDSEVASSIEKAVAGAPGKSGY
                     NVPAILEALGGADNIVSLDNCITRLRLSVKDMSLVNVQALKDNRAIGVVQLNQHNLQV
                     VIGPQVQSVKDEMAGLMHTVQA"
     gene            71306..72334
                     /gene="malI"
                     /locus_tag="IRB70_000506"
     CDS             71306..72334
                     /gene="malI"
                     /locus_tag="IRB70_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mal regulon transcriptional regulator MalI"
                     /protein_id="HBC0630461.1"
                     /translation="MATAKKITIHDVALAAGVSVSTVSLVLSGKGRISTSTGERVNAA
                     IEELGFVRNRQASALRGGQSGVIGLIVRDLSAPFYAELTAGLTEALEAQGRMVFLLHG
                     GKDGEQLAQRFSLLLNQGVDGVVIAGAAGSSDDLRRMAEEKAIPVIFASRASYLDDVD
                     TVRPDNMQAAQLLTEHLIRNGHQRIAWLGGQSSSLTRAERVGGYCATLLKFGLPFHSD
                     WVLECSSSQKQAAEAITALLRHNPTISAVVCYNETIAMGAWFGLLKAGRQSGESGVDR
                     YFEQQVSLAAFTDATPTTLDDIPVTWASTPARELGTTLADRMMQKITHEETHSRNFII
                     PARLIAAK"
     gene            72446..73213
                     /gene="hdhA"
                     /locus_tag="IRB70_000507"
     CDS             72446..73213
                     /gene="hdhA"
                     /locus_tag="IRB70_000507"
                     /EC_number="1.1.1.159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-alpha-hydroxysteroid dehydrogenase"
                     /protein_id="HBC0630462.1"
                     /translation="MFNSDNLRLDGKCAIITGAGAGIGKEIAITFATAGASVVVSDIN
                     ADAANHVVDEIQQLGGQAFACRCDITSEQELSALADFAVSKLGKVDILVNNAGGGGPK
                     PFDMPMADFRRAYELNVFSFFHLSQLVAPKMEKNGGGVILTITSMAAENKNINMTSYA
                     SSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQKMLQHTPIRRL
                     GQPQDIANAALFLCSPAASWVSGQILTVSGGGVQELN"
     gene            73442..74032
                     /gene="uidR"
                     /locus_tag="IRB70_000508"
     CDS             73442..74032
                     /gene="uidR"
                     /locus_tag="IRB70_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator UidR"
                     /protein_id="HBC0630463.1"
                     /translation="MMDNMQTEAQPTRTRILNAAREIFSENGFHSASMKAICKSCAIS
                     PGTLYHHFISKEALIQAIILQDQERALARFREPIEGIHFVDYMVESIVSLTHEAFGQR
                     ALVVEIMAEGMRNPQVAAMLKNKHMTITEFVAQRMRDAQQKGEISPDINTAMTARLLL
                     DLTYGVLADIEAEDLAREASFAQGLRAMIGGILTAS"
     gene            74422..74607
                     /locus_tag="IRB70_000509"
                     /pseudo
     CDS             74422..74607
                     /locus_tag="IRB70_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
     gene            complement(74801..76309)
                     /locus_tag="IRB70_000510"
     CDS             complement(74801..76309)
                     /locus_tag="IRB70_000510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdgA family protein"
                     /protein_id="HBC0630464.1"
                     /translation="MNKSLVAVGVIVALGVVWTGGAWYTGKKIETHLEDMVAQANAQL
                     KLTAPESNLEVSYQNYHRGVFSSQLQLLVKPIAGKENPWIKSGQSVIFNESVDHGPFP
                     RAQLKKLNLIPSMASIQTTLVNNEVSKPLFDMAKGETPFEINSRIGYSGDSSSDISLK
                     PLNYEQKDEKVAFSGGEFQLNADRDGKAISLSGEAESGRIDAVNEYNQKVQLTFNNLK
                     TDGSSTLASFGERVGNQKLSLEKMTISVEGKELALLEGMEISGKSDLVNDGKTINSQL
                     DYSLNSLKVQNQDLGSGKLTLKVGQIDGEAWHQFSQQYNAQTQALLAQPKIANNPELY
                     QEKVTEAFFSALPLMLKGDPVITIAPLSWKNSQGESALNLSLFLKDPATTKEAPQTLA
                     QEVDRSVKSLDAKLTIPVDMATELMTQVAKLEGYQEDQAKKLAKQQVEGASAMGQMFR
                     LTTLQDNTITTSLQYANGQITLNGQKMPLEDFVGMFAMPTLNVPAVPAIPQQ"
     gene            complement(76410..77585)
                     /gene="manA"
                     /locus_tag="IRB70_000511"
     CDS             complement(76410..77585)
                     /gene="manA"
                     /locus_tag="IRB70_000511"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416130.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase"
                     /protein_id="HBC0630465.1"
                     /translation="MQKLINSVQNYAWGSKTALTELYGMENPSSQPMAELWMGAHPKS
                     SSRVQNAAGDIVSLRDVIESDKATLLGDAVAKRFGELPFLFKVLCAAQPLSIQVHPNK
                     RNSEIGFAKENAAGIPMDAAERNYKDPNHKPELVFALTPFLAMNAFRDLSEIVSLLQP
                     VAGAHPAIAHFLQQPDAERLSELFASLLNMQGEEKSRALAILKSALDSQQGEPWQTIR
                     LISEFYPEDSGLFSPLLLNVVKLNPGEAMFLFAETPHAYLQGVALEVMANSDNVLRAG
                     LTPKYIDIPELVANVKFEAKPANQLLTQPVKQGAELDFPIPVDDFAFSLHDLSDKETN
                     ISQQSAAILFCVEGDATLCKGSQQLQLKPGESAFIAANESPVTVKGHGRLARVYNKL"
     gene            77784..79430
                     /gene="fumB"
                     /locus_tag="IRB70_000512"
     CDS             77784..79430
                     /gene="fumB"
                     /locus_tag="IRB70_000512"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000066594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HBC0630466.1"
                     /translation="MSNKPFHYQAPFPLKKDDTEYYLLTSEHVSVSEFEGQEILKVAP
                     EALTLLARQAFHDASFMLRPAHQQQVADILRDPEASENDKYVALQFLRNSDIAAKGIL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEAALARGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCIAKGGGSANKTYLYQETKALLTPGKLKNYLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAKYYDELPTEGNEHGQAFRDVELEKEL
                     LIEAQNLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINRQGIW
                     IEKLEHNPGKYIPEELRKAGEGEAVRVDLNRPMKEILAQLSQYPVSTRLSLNGTIIVG
                     RDIAHAKLKERMDNGEGLPQYIKDHPIYYAGPAKTPEGYASGSLGPTTAGRMDSYVDQ
                     LQAQGGSMIMLAKGNRSQQVTDACKKHGGFYLGSIGGPAAVLAQGSIKSLECVEYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIQLTQCTRCVK"
     gene            79573..80976
                     /gene="fumC"
                     /locus_tag="IRB70_000513"
     CDS             79573..80976
                     /gene="fumC"
                     /locus_tag="IRB70_000513"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fumarate hydratase"
                     /protein_id="HBC0630467.1"
                     /translation="MNTVRSEKDSMGAIDVPADKLWGAQTQRSLEHFRISTEKMPTSL
                     IHALALTKRAAAKVNEDLGLLSEEKASAIRQAADEVLAGQHDDEFPLAIWQTGSGTQS
                     NMNMNEVLANRASELLGGVRGMERKVHPNDDVNKSQSSNDVFPTAMHVAALLALRKQL
                     IPQLKTLTQTLSEKSRAFADIVKIGRTHLQDATPLTLGQEISGWVAMLEHNLKHIEYS
                     LPHVAELALGGTAVGTGLNTHPEYARRVADELAVITCAPFVTAPNKFEALATCDALVQ
                     AHGALKGLAASLMKIANDVRWLASGPRCGIGEISIPENEPGSSIMPGKVNPTQCEALT
                     MLCCQVMGNDVAINMGGASGNFELNVFRPMVIHNFLQSVRLLADGMESFNKHCAVGIE
                     PNRERINQLLNESLMLVTALNTHIGYDKAAEIAKKAHKEGLTLKAAALALGYLSEAEF
                     DSWVRPEQMVGSMKAGR"
     gene            complement(80973..81902)
                     /gene="tus"
                     /locus_tag="IRB70_000514"
     CDS             complement(80973..81902)
                     /gene="tus"
                     /locus_tag="IRB70_000514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication terminus site-binding protein"
                     /protein_id="HBC0630468.1"
                     /translation="MARYDLVDRLNTTFRQMEQELAAFAAHLEQHKLLVARVFSLPEV
                     KKEDEHNPLNRIEVKQHLGNDAQSLALRHFRHLFIQQQSENRSSKAAVRLPGVLCYQV
                     DNLSQAALVSHIQHINKLKTTFEHIVTVESELPTAARFEWVHRHLPGLITLNAYRTLT
                     VLHDPATLRFGWANKHIIKNLHRDEVLAQLEKSLKSPRSVAPWTREEWQRKLEREYQD
                     IAALPQNAKLKIKRPVKVQPIARVWYKGDQKQVQHACPTPLIALINRDNGAGVPDVGE
                     LLNYDADNVQHRYKPQAQPLRLIIPRLHLYVAD"
     gene            complement(81978..83279)
                     /gene="rstB"
                     /locus_tag="IRB70_000515"
     CDS             complement(81978..83279)
                     /gene="rstB"
                     /locus_tag="IRB70_000515"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RstB"
                     /protein_id="HBC0630469.1"
                     /translation="MKKLFIQFYLLLFVCFLVMSLLVGLVYKFTAERAGKQSLDDLMN
                     SSLYLMRSELREIPPHDWGKTLKEMDLNLSFDLRVEPLSKYHLDDISMHRLRGGEIVA
                     LDDQYTFLQRIPRSHYVLAVGPVPYLYYLHQMRLLDIALIAFIAISLAFPVFIWMRPH
                     WQDMLKLEAAAQRFGDGHLNERIHFDEGSSFERLGVAFNQMADNINALIASKKQLIDG
                     IAHELRTPLVRLRYRLEMSDNLSAAESQALNRDISQLEALIEELLTYARLDRPQNELH
                     LSEPDLPLWLSTHLADIQAVTPDKTVRIKTLAQGHYAALDMRLMERVLDNLLNNALRY
                     CHSTVETSLLLSGNRATLIVEDDGPGIAPENREHIFEPFVRLDPSRDRSTGGCGLGLA
                     IVHSIALAMGGTANCDTSELGGARFSFSWPLWHNIPQFTSA"
     gene            complement(83283..84002)
                     /gene="rstA"
                     /locus_tag="IRB70_000516"
     CDS             complement(83283..84002)
                     /gene="rstA"
                     /locus_tag="IRB70_000516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416125.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RstA"
                     /protein_id="HBC0630470.1"
                     /translation="MNTIVFVEDDAEVGSLIAAYLAKHDMQVTVEPRGDRAEETILRE
                     NPDLVLLDIMLPGKDGMTICRDLRAKWSGPIVLLTSLDSDMNHILALEMGACDYILKT
                     TPPAVLLARLRLHLRQNEQATVTKGIQETSLTPYKALHFGTLTIDPINRVVTLANTEI
                     SLSTADFELLWELATHAGQIMDRDALLKNLRGVSYDGLDRSVDVAISRLRKKLLDNAA
                     EPYRIKTVRNKGYLFAPHAWE"
     gene            84131..84466
                     /locus_tag="IRB70_000517"
     CDS             84131..84466
                     /locus_tag="IRB70_000517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlpM family protein"
                     /protein_id="HBC0630471.1"
                     /translation="MGLVIKAALGALVVLLIGVLAKTKNYYIAGLIPLFPTFALIAHY
                     IVASERGIEALRATIIFSMWSIIPYFVYLASLWYFTGMMRLPAAFVGSVACWGISAWV
                     LIICWIKLH"
     gene            complement(84463..85185)
                     /gene="folM"
                     /locus_tag="IRB70_000518"
     CDS             complement(84463..85185)
                     /gene="folM"
                     /locus_tag="IRB70_000518"
                     /EC_number="1.5.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydromonapterin reductase"
                     /protein_id="HBC0630472.1"
                     /translation="MGKTQPLPILITGGGRRIGLALAWHFINQKQPVIISYRTHYPAI
                     DGLINAGAQCIQADFSTNDGVMAFADEVLKSTHGLRAILHNASAWMAEKPGALLTDVL
                     ACMMQIHVNTPYLLNHALERLLRGHGHAASDIIHFTDYVVERGSDKHIAYAASKAALD
                     NMTRSFARKLAPEVKVNSIAPSLILFNEHDDAEYRQQALNKSLMKTAPGEKEVIDLVD
                     YLLTSCFVTGRSFPLDGGRHLR"
     gene            complement(85222..86604)
                     /locus_tag="IRB70_000519"
     CDS             complement(85222..86604)
                     /locus_tag="IRB70_000519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBC0630473.1"
                     /translation="MEKKLGLSALTALVLSSMLGAGVFSLPQNMAAVASPAALLIGWG
                     ITGAGILLLAFAMLILTRIRPELDGGIFTYAREGFGELIGFCSAWGYWLCAVIANVSY
                     LVIVFSALSFFTDTPELRLFGDGNTWQSIVGASALLWIVHFLILRGVQTAASINLVAT
                     LAKLLPLGLFVVLAMMMFKLDTFKLDFTGLALGVPVWEQVKNTMLITLWVFIGVEGAV
                     VVSARARNKRDVGKATLLAVLSALGVYLLVTLLSLGVVARPELAEIRNPSMAGLMVEM
                     MGPWGEIIIAAGLIVSVCGAYLSWTIMAAEVPFLAATHKAFPRIFARQNAQAAPSASL
                     WLTNICVQICLVLIWLTGSDYNTLLTIASEMILVPYFLVGAFLLKIATRPLHKAVGVG
                     ACIYGLWLLYASGPMHLLLSVVLYAPGLLVFLYARKTHTHDNVLNRQEMVLIGMLLIA
                     SVPATWMLVG"
     gene            complement(86790..87734)
                     /locus_tag="IRB70_000520"
     CDS             complement(86790..87734)
                     /locus_tag="IRB70_000520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBC0630474.1"
                     /translation="MKLKNTLLASALLSATAFSVNAATELTPEQAAAVKPFDRVVVTG
                     RFNAIGEAVKAVSRRADKEGAASFYVVDTSDFGNSGNWRVVADLYKADAEKAEETSNR
                     VINGVVELPKDQAVLIEPFDTVTVQGFYRSQPEVNDAITKAAKAKGAYSFYIVRQIDA
                     NQGGNQRITAFIYKKDAKKRIVQSPDVIPADSEAGRAALAAGGEAAKKVEIPGVATTA
                     SPSSEVGRFFETQSSKGGRYTVTLPDGTKVEELNKATAAMMVPFDSIKFSGNYGNMTE
                     VSYQVAKRAAKKGAKYYHITRQWQERGNNLTVSADLYK"
     gene            88258..89790
                     /gene="pntA"
                     /locus_tag="IRB70_000521"
     CDS             88258..89790
                     /gene="pntA"
                     /locus_tag="IRB70_000521"
                     /EC_number="1.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit alpha"
                     /protein_id="HBC0630475.1"
                     /translation="MRIGIPRERLTNETRVAATPKTVEQLLKLGFTVAVESGAGQLAS
                     FDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLDDEIALLNPGTTLVSFIWPAQNPELM
                     QKLAERNVTVMAMDSVPRISRAQSLDALSSMANIAGYRAIVEAAHEFGRFFTGQITAA
                     GKVPPAKVMVIGAGVAGLAAIGAANSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKE
                     EAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGKPAPKLITREMVDSMK
                     AGSVIVDLAAQNGGNCEYTVPGEIFTTENGVKVIGYTDLPGRLPTQSSQLYGTNLVNL
                     LKLLCKEKDGNITVDFDDVVIRGVTVIRAGEITWPAPPIQVSAQPQAAQKAAPEVKTE
                     EKCACSPWRKYALMALAIILFGWMASVAPKEFLGHFTVFALACVVGYYVVWNVSHALH
                     TPLMSVTNAISGIIVVGALLQIGQGGWVSFLSFIAVLIASINIFGGFTVTQRMLKMFR
                     KN"
     gene            89801..91189
                     /gene="pntB"
                     /locus_tag="IRB70_000522"
     CDS             89801..91189
                     /gene="pntB"
                     /locus_tag="IRB70_000522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000014033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Re/Si-specific NAD(P)(+) transhydrogenase
                     subunit beta"
                     /protein_id="HBC0630476.1"
                     /translation="MSGGLVTAAYIVAAILFIFSLAGLSKHETSRQGNNFGIAGMAIA
                     LIATIFGPDTGNVGWILLAMVIGGAIGIRLAKKVEMTEMPELVAILHSFVGLAAVLVG
                     FNSYLHHDAGMAPILVNIHLTEVFLGIFIGAVTFTGSVVAFGKLCGKISSKPLMLPNR
                     HKMNLAALVVSFLLLIVFVRTDSVGLQVLALLIMTAIALVFGWHLVASIGGADMPVVV
                     SMLNSYSGWAAAAAGFMLSNDLLIVTGALVGSSGAILSYIMCKAMNRSFISVIAGGFG
                     TDGSSTGDDQEVGEHREITAEETAELLKNSHSVIITPGYGMAVAQAQYPVAEITEKLR
                     ARGINVRFGIHPVAGRLPGHMNVLLAEAKVPYDIVLEMDEINDDFADTDTVLVIGAND
                     TVNPAAQDDPKSPIAGMPVLEVWKAQNVIVFKRSMNTGYAGVQNPLFFKENTHMLFGD
                     AKASVDAILKAL"
     gene            complement(91214..92248)
                     /gene="tqsA"
                     /locus_tag="IRB70_000523"
     CDS             complement(91214..92248)
                     /gene="tqsA"
                     /locus_tag="IRB70_000523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2 transporter TqsA"
                     /protein_id="HBC0630477.1"
                     /translation="MAKPIITLNGLKIVIMLGMLVIILCGIRFAAEIIVPFILALFIA
                     VILNPLVQHMVRWRVPRVLAVSILMTIIVMAMVLLLAYLGSALNELTRTLPQYRNSIM
                     TPLQAIEPLLQRVGIDVSVDQLAHYIDPNAAMTLLTNLLTQLSNAMSSIFLLLLTVLF
                     MLLEVPQLPGKFQQMMVRPVEGMAAIQRAIDSVSHYLVLKTAISIITGLVAWAMLAAL
                     DVRFAFVWGLLAFALNYIPNIGSVLAAIPPIAQVLVFNGFYEALLVLAGYLLINLVFG
                     NILEPRIMGRGLGLSTLVVFLSLIFWGWLLGPVGMLLSVPLTIIVKIALEQTAGGQSI
                     AVLLSDLNKE"
     gene            92660..93025
                     /gene="mdtJ"
                     /locus_tag="IRB70_000524"
     CDS             92660..93025
                     /gene="mdtJ"
                     /locus_tag="IRB70_000524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtJ"
                     /protein_id="HBC0630478.1"
                     /translation="MYIYWILLGLAIATEITGTLSMKWASVSEGNGGFILMLVMISLS
                     YIFLSFAVKKIALGVAYALWEGIGILFITLFSVLLFDESLSLMKIAGLTTLVAGIVLI
                     KSGTRKARKPELEVNHGAV"
     gene            93012..93341
                     /gene="mdtI"
                     /locus_tag="IRB70_000525"
     CDS             93012..93341
                     /gene="mdtI"
                     /locus_tag="IRB70_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug/spermidine efflux SMR transporter
                     subunit MdtI"
                     /protein_id="HBC0630479.1"
                     /translation="MAQFEWVHAAWLALAIVLEIVANVFLKFSDGFRRKIFGLLSLAA
                     VLAAFSALSQAVKGIDLSVAYALWGGFGIAATLAAGWILFGQRLNRKGWIGLVLLLAG
                     MIMVKLA"
     gene            complement(93380..94201)
                     /locus_tag="IRB70_000526"
     CDS             complement(93380..94201)
                     /locus_tag="IRB70_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease"
                     /protein_id="HBC0630480.1"
                     /translation="MRTTIAVVLGAISLTSAFVFADKPDVAKSANDEVSTLFFGHDDR
                     VPVNDTTQSPWDAVGQLETASGNLCTATLIAPNLALTAGHCLLTPPKGKADKAVALRF
                     VSNKGLWRYEIHDIEGRVDPTLGKRLKADGDGWIVPPAAAPWDFGLIVLRNPPSGITP
                     LPLFEGDKAALTAALKAAGRKVTQAGYPEDHLDTLYSHQNCEVTGWAQTSVMSHQCDT
                     LPGDSGSPLMLHTDDGWQLIGVQSSAPAAKDRWRADNRAISVTGFRDKLDQLSQK"
     gene            complement(94301..94384)
                     /locus_tag="IRB70_000527"
     CDS             complement(94301..94384)
                     /locus_tag="IRB70_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630481.1"
                     /translation="MVGRYRFEFILIILILCALIAARFYLS"
     gene            complement(94477..94812)
                     /locus_tag="IRB70_000528"
     CDS             complement(94477..94812)
                     /locus_tag="IRB70_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310330.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid shock protein"
                     /protein_id="HBC0630482.1"
                     /translation="MKKQIEGMTMKKVLALVVAAAMGLSSAAFAAETATTPAPTATTT
                     KAAPAKTTHHKKQHKAAPAQKAQAAKKHHKNAKAEQKAPEQKAQAAKKHAKKHSHQQP
                     AKPAAQPAA"
     gene            complement(95209..96462)
                     /locus_tag="IRB70_000529"
     CDS             complement(95209..96462)
                     /locus_tag="IRB70_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630483.1"
                     /translation="MSRTTTVDGAPASDTDKQSISQPNQFIKRGTPQFMRVTLALFSA
                     GLATFALLYCVQPILPVLSQEFGLTPANSSISLSISTAMLAIGLLFTGPLSDAIGRKP
                     VMVTALLLASICTLLSTMMTSWHGILIMRALIGLSLSGVAAVGMTYLSEEIHPSFVAF
                     SMGLYISGNSIGGMSGRLISGVFTDFFNWRIALAAIGCFALASALMFWKILPESRHFR
                     PTSLRPKTLFINFRLHWRDRGLPLLFAEGFLLMGSFVTLFNYIGYRLMLSPWHVSQAV
                     VGLLSLAYLTGTWSSPKAGTMTTRYGRGPVMLFSTGVMLFGLLMTLFSSLWLIFAGML
                     LFSAGFFAAHSVASSWIGPRAKRAKGQASSLYLFSYYLGSSIAGTLGGVFWHNYGWNG
                     VGAFIALMLVIALLVGTRLHRRLHA"
     gene            96569..97462
                     /locus_tag="IRB70_000530"
     CDS             96569..97462
                     /locus_tag="IRB70_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0630484.1"
                     /translation="MNIELRHLRYFVAVAEELHFGRAAARLNISQPPLSQQIQALEQQ
                     IGARLLARTNRSVLLTAAGKQFLADSRQILSMVDDAAARAERLHQGEAGELRIGFTSS
                     APFIRAVSDTLSLFRRDYPDVHLQTREMNTREQIAPLIEGTLDMGLLRNTALPETLEH
                     AVIVHEPLMAMIPHDHPLANNPNVTLAELAKEPFVFFDPHVGTGLYDDILGLMRRYHL
                     TPVITQEVGEAMTIIGLVSAGLGVSILPASFKRVQLNEMRWVPIAEEDAVSEMWLVWP
                     KHHEQSPAARNFRIHLLNALR"
     gene            97597..98817
                     /gene="mlc"
                     /locus_tag="IRB70_000531"
                     /gene_synonym="dgsA"
     CDS             97597..98817
                     /gene="mlc"
                     /locus_tag="IRB70_000531"
                     /gene_synonym="dgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor Mlc"
                     /protein_id="HBC0630485.1"
                     /translation="MVAENQPGHIDQIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAP
                     ASITKIVREMLEAHLVQELEIKEAGNRGRPAVGLVVETEAWHYLSLRISRGEIFLALR
                     DLSSKLVVEEAQELALKDDSPLLDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTE
                     NGIVHRMPFYEDVKEMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQV
                     VIDHNVGAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSILE
                     LAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGRILAIMVNLFN
                     PQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVESTQFSNQGTMAGAALVKD
                     AMYNGSLLIRLLQG"
     gene            98942..99637
                     /gene="bioD"
                     /locus_tag="IRB70_000532"
     CDS             98942..99637
                     /gene="bioD"
                     /locus_tag="IRB70_000532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310326.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent dethiobiotin synthetase BioD"
                     /protein_id="HBC0630486.1"
                     /translation="MLKRFFITGTDTSVGKTVVSRALLQALASQGKTVAGYKPVAKGS
                     KETPEGLRNKDALVLQSVSTIELPYEAVNPIALSEEESSVAHSCPINYTLISNGLANL
                     TDKVDHVVVEGTGGWRSLMNDLRPLSEWVVQEQLPVLMVVGIQEGCINHALLTAQAIA
                     NDGLPLIGWVANRINPGLAHYAEIIDVLGKKLPAPLIGELPYLPRAEQRELGQYIRLA
                     MLRSVLAVDRVTV"
     gene            complement(99590..100882)
                     /gene="clcB"
                     /locus_tag="IRB70_000533"
     CDS             complement(99590..100882)
                     /gene="clcB"
                     /locus_tag="IRB70_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated ClC-type chloride channel ClcB"
                     /protein_id="HBC0630487.1"
                     /translation="MHHLHIYPDLRTMFRRLLIATVVGILAAFAVAGFRHAMLLLEWL
                     FLNNDSGSLVNAATNLSPWRRLLTPALGGLAAGLLLMGWQKFTQQRPHAPTDYMEALQ
                     TDGQFDYAASLVKSLASLLVVTSGSAIGREGAMILLAALAASCFAQRFTPRQEWKLWI
                     ACGAAAGMAAAYRAPLAGSLFIAEVLFGTMMLASLGPVIISAVVALLVSNLINHSDAL
                     LYSVQLSVTVQARDYALIISTGVLAGLCGPLLLTLMNACHRGFVSLKLAPPWQLALGG
                     LIVGLLSLFTPAVWGNGYSTVQSFLTAPPLLMIIAGIFLCKLFAVLASSGSGAPGGVF
                     TPTLFIGLAIGMLYGRSLGLWFPDGEEITLLLGLTGMATLLAATTHAPIMSTLMICEM
                     TGEYQLLPGLLIACVIASVISRTLHRDSIYRQHTAKHS"
     gene            complement(101041..101655)
                     /gene="dmsD"
                     /locus_tag="IRB70_000534"
     CDS             complement(101041..101655)
                     /gene="dmsD"
                     /locus_tag="IRB70_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707489.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tat proofreading chaperone DmsD"
                     /protein_id="HBC0630488.1"
                     /translation="MTHFSQQDNFSVAARVLGALFYYAPESAEAAPLVAVLTNDSWET
                     QWPLPEASLAPLVTAFQTQSEETHAQAWQRLFVGPWALPSPPWGSVWLDRESVLFGDS
                     TLALRQWMREKGIQFEMQQNEPEDHFGSLLLMAAWLAENGRQTECEELLAWHLFPWST
                     RFLDVFIEKAEHPFYRALGELARLTLAQWQSQLLIPVAVKPLFR"
     gene            complement(101698..102552)
                     /locus_tag="IRB70_000535"
     CDS             complement(101698..102552)
                     /locus_tag="IRB70_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit"
                     /protein_id="HBC0630489.1"
                     /translation="MGNGWHEWPLVIFTVLGQCVVGALIVSGIGWFAAKNDADRQRIV
                     RGMFFLWLLMGIGFIASVMHLGSPLRAFNSLNRIGDSGLSNEIAAGSIFFAVGGLWWL
                     VAVIGKMPQALGKLWLLVSMALGVIFVWMMTCVYQIDTVPTWHNGYTTLAFFLTVLLS
                     GPILAAAILRAARVTFNTTPFAIISVLALIACAGVIVLQGLSLASIHSSVQQASALVP
                     DYASLQVWRVVLLCAGLGCWLCPLIRRREPHVAGLVLGLILILGGEMIGRVLFYGLHM
                     TVGMAIAG"
     gene            complement(102554..103171)
                     /gene="dmsB"
                     /locus_tag="IRB70_000536"
     CDS             complement(102554..103171)
                     /gene="dmsB"
                     /locus_tag="IRB70_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HBC0630490.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDFKDLGPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCDDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNAEKGHMTKCDGCYSRVAEGKQPICVESCPLRALEFGPIEELRQ
                     KHGTLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPEEV"
     gene            complement(103182..105605)
                     /locus_tag="IRB70_000537"
     CDS             complement(103182..105605)
                     /locus_tag="IRB70_000537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416105.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HBC0630491.1"
                     /translation="MKIHTTEALMKAEISRRSLMKTSALGSLALASSAFTLPFSQMVR
                     AAETPVEEKAVWSSCTVNCGSRCLLRLHVKDDTVYWVESDTTGDDVYGNHQVRACLRG
                     RSIRRRMNHPDRLKYPMKRVGKRGEGKFERISWDEALDTISDNLRRILKDYGNEAVHV
                     LYGTGVDGGNITNSNVPYRLMNSCGGFLSRYGSYSTAQISAAMSYMFGANDGNSPDDI
                     ANTKLVVMFGNNPAETRMSGGGVTYYVEQARERSNARMIVIDPRYNDTAAGREDEWLP
                     IRPGTDGALACAIAWVLITENMVDQPFLDKYCVGYDEKTLPANAPRNAHYKAYILGEG
                     PDGIAKTPEWAAKITSIPAEKIIQLAREIGSAKPAYICQGWGPQRHSNGEQTSRAIAM
                     LSVLTGNVGINGGNSGVREGSWDLGVEWFPMLENPVKTQISVFTWTDAIDHGTEMTAT
                     RDGVRGKEKLDVPIKFLWCYASNTLINQHGDINHTHEVLQDDSKCEMIVGIDHFMTAS
                     AKYCDILLPDLMPTEQEDLISHESAGNMGYVILAQPATSAKFERKPIYWILSEVAKRL
                     GPDVYQTFTEGRSQHEWIKYLHAKTKERNPEMPDYEEMKTTGIFKKKCPEEHYVAFRA
                     FREDPQANPLKTPSGKIEIYSERLATIADTWELKKDEIIHPLPAYTPGFDGWDDPLRK
                     TYPLQLTGFHYKARTHSSYGNIDVLQQACPQEVWINPIDAQARGIRHGDTVRVFNTNG
                     EMLIAAKVTPRILPGVTAIGQGAWLKADMFGDRVDHGGSINILTSHRPSPLAKGNPSH
                     SNLVQIEKV"
     gene            complement(105666..108092)
                     /locus_tag="IRB70_000538"
     CDS             complement(105666..108092)
                     /locus_tag="IRB70_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase subunit A"
                     /protein_id="HBC0630492.1"
                     /translation="MSKNEQMVGISRRTLVKSTAIGSLALAAGGFSLPFTLRSAAAAV
                     QQASEKVVWGACSVNCGSRCALRLHVKDNEVTWVETDNTGNDEYGNHQVRACLRGRSI
                     RRRINHPDRLNYPMKRVGKRGEGKFERISWDEALDTIASSLKKTVEQYGNEAVYIQYS
                     SGIVGGNMTRSSPSASAVKRLMNCYGGSLNQYGSYSTAQISCAMPYTYGSNDGNSTTD
                     IENSKLVVMFGNNPAETRMSGGGITYLLEKAREKSNAKMIVIDPRYTDTAAGREDEWL
                     PIRPGTDAALVAGIAWVLINENLVDQPFLDKYCVGYDEKTLPADAPINGHYKAYILGE
                     GDDKTAKTPQWASQITGIPVDRIIKLAREIGTAKPAYICQGWGPQRQANGELTARAIA
                     MLPILTGNVGISGGNSGARESTYTITIERLPVLDNPVKTSISCFSWTDAIDHGPQMTA
                     IRDGVRGKDKLDVPIKFIWNYAGNTLVNQHSDINKTHEILQDESKCEMIVVIENFMTS
                     SAKYADILLPDLMTVEQEDIIPNDYAGNMGYLIFLQPVTSEKFERKPIYWILSEVAKR
                     LGPDVYQKFTEGRTQEQWLQHLYAKMLAKDPALPSYDELKKMGIYKRKDPNGHFVAYK
                     AFRDDPEANPLKTPSGKIEIYSSKLAEIARTWELEKDEVISPLPVYASTFEGWDSPER
                     STFPLQLFGFHYKSRTHSTYGNIDVLKAACRQEVWINPIDAQKRGIANGDMVRVFNHR
                     GEVRLPAKVTPRILPGVSAMGQGAWHEANMSGDKIDHGGCVNTLTTLRPSPLAKGNPQ
                     HTNLVEIEKI"
BASE COUNT        27236 a        26696 c        28072 g        26125 t
ORIGIN      
        1 aaatgttaaa aaaaagccca tcgtgggaga tgggcaaaga ctacacacag caattcgttg
       61 tttcactcag gggatttcca tgcttataaa tcaatatgtt gatttataac cgtgagctaa
      121 tagtaggcat acggactttt tgcgtcgatc agattcgtct cattagttta aaaactgtaa
      181 agaatttgcg acaggtacta ccagctgaat ggcggtaagc aggaaaatat ggggaagagc
      241 aagcaaatat caattagcag gggttaacaa tcaggcggca gagccgcctg atgagaaatt
      301 acttattcga tttctcgatt tcgccaagtt cttcgagaat ttcttccggt tggtccgtcg
      361 gcggtgggac ttcttccacc cacgcggcaa aaagacgcca ggaaacggct aacagaaccg
      421 gaccaataaa caggccgatc atcccgaaag caatcaaacc accaataacg ccagagagaa
      481 tcaggatcag cggtaaatcg gcacccatgc gaattaacat tgggcggatg acgttatcca
      541 gcgtgccaac cacaccgctc cacactaaca ataccgttcc ccaggtggta tcgccagtcc
      601 agtagagcca gataatcgcc ggaatcagta ccggcaacgg tccaagctgg acaaggcagg
      661 agaggatcat taacaccgtg agcaaagttg cataaggtac gccggatacg gcgaggccga
      721 taccgccaag cactgcctgt actaacgctg tcaccacaac acccagcgcc accgcgcgga
      781 tagcctgtgc cgccagcagc acggcggcat ctccacgaac gcctgccaga cgggttgcaa
      841 aatggcgaat gccttgtgcc acctgttcac cgcgccagta cagcagggcg ctgaagagaa
      901 gcatcagcgc acaatgcacc ataaagcgcc cgatatgcgc cgcctgccca acgaaccagg
      961 tggtggtggt gccaatataa ggacggactt ttgccatgat cgccgtcccc cccatatcca
     1021 gcaagttgtg ccagcctgca tatagcttcg cgccaatcac cggaatggta ttaagccacg
     1081 ccagatcggg taacgtcatg tcaccgctgg aaatggcttt aattagcggg ccgctgccgt
     1141 cgacgatact gttaaccagc aaggcaatag ggatgataaa caccatcact aataacagcg
     1201 tcatcaccag aacggcgaga gagcggcgac caaacatgaa cttttgcaaa cgtaacaata
     1261 ccggccaggt ggcgataacc accgtaccag cccatgcaaa gccgagaata aagggttgta
     1321 caatccacag acatgccaca atcatgatgg ctaaaaagag caccgaaagc agaatttgtg
     1381 cgacatccct gggctgacga acatttacca taactacttt tcaccttttt tgtgcgtcaa
     1441 atcgtcgacg cgacgtgaac acgcgaaact cacctgcata atgatgagca atttcagcgg
     1501 tttttaacag gccgattctg cccttaattc tgatgggcgt gttagaaaaa aatgtggtac
     1561 aacaactcag gcaacacgca aacgatttac tcgtcgtatt ttaaattgca tgtgctgcgg
     1621 ctacgttcgt tcaccccagt cacttactat tgtaagctcc tggagttcac tcgcttgccg
     1681 ccttcctgca acacgaaatc catagagtaa acaaacatca cctttcagtg cgctattgca
     1741 gcagcctgaa agaacagtgt atcgacctac atcacagacc gcaggaaagg gtcaatataa
     1801 tgattccaca gatttcccag gcacccggcg tcgttcaact ggtgcttaat tttttgcaag
     1861 agctggagca acaaggtttt accggcgata cggcgacaag ttatgccgat cgtttgacaa
     1921 tgtcgaccga caacagtatt taccaacttc tccccgatgc ggtggtattt ccgcgttcaa
     1981 ccgcagatgt ggcgctgatc gcccgtcttg ccgcgcagga acgctattca tcgctgatct
     2041 ttaccccccg aggcggcggc accggcacta acggtcaggc gctcaaccag gggattattg
     2101 ttgatatgtc ccgccatatg aaccgcatca tcgaaattaa ccctgaagag ggctgggtgc
     2161 gcgttgaggc cggggtgata aaagatcaac tcaatcagta cctgaaaccg ttcggctact
     2221 tttttgcgcc ggaactttcc accagcaacc gggcaacgct cggcgggatg atcaataccg
     2281 atgcatccgg tcagggatcg ctggtctatg gcaaaacgtc agatcacgta cttggcgtac
     2341 gcgcggtgtt gttggggggc gatattctcg atacgcaacc tttacccgtc gaactggcgg
     2401 aaacgctggg taaatccaat accacaatcg ggcgaattta taacacggtt tatcaacgtt
     2461 gccgtcagca acgccagtta atcatcgaca acttccccaa gcttaaccgc tttcttaccg
     2521 gttacgatct gcgtcatgtc tttaacgatg agatgaccga gttcgatctg acgcgcattc
     2581 tgacgggttc agaagggacg ctggccttta ttaccgaagc gcggctggat attacgcgct
     2641 tgcctaaagt gcgccgtctg gtgaacgtca aatatgactc ttttgactct gcgctgcgta
     2701 acgcgccgtt tatggttgag gcgcgggcgc tttcggtaga gacggttgac tcaaaagtgc
     2761 tgaatctggc gcgggaagat attgtctggc attccgtcag cgagttgatt accgatgtac
     2821 ctgacaaaga aatgctcggg ctgaatattg ttgaatttgc cggcgatgat gaggcgctga
     2881 ttgacgagag ggtaagtgca ctctgtgcgc gactgaatga gttaatcgcc agccagcaag
     2941 caggtgtgat cggctggcag gtatgcagtg agctggcagg tgttgaacgt atctatgcga
     3001 tgcgcaaaaa agctgtcggc ctgctcggta atgccaaagg agcagccaag ccaattccgt
     3061 ttgctgagga tacctgcgta ccgccggaac atctggccga ttatattgct gaatttcgcg
     3121 cgctgctcga cagccacggc ttaagctacg gtatgttcgg tcacgtcgac gcaggtgtct
     3181 tgcacgtccg tccggcactg gatatgtgcg atccacaaca agagattttg atgaagcaaa
     3241 tctctgatga cgtggtggcg ctgactgcga aatacggtgg tttgttgtgg ggcgagcacg
     3301 gcaaaggttt tcgcgctgaa tacagcccgg cgtttttcgg tgaggaactt tttgcagaac
     3361 tgcgcaaagt gaaagcggca tttgacccgc ataaccgact caacccaggg aagatttgcc
     3421 cgccagaagg tctcgatgcg ccgatgatga aagtggacgc ggtgaagcgc ggtacatttg
     3481 atcggcagat ccccattgcg gtacgccagc agtggcgcgg tgcgatggag tgtaacggca
     3541 acggtttatg cttcaacttt gatgcccgta gtccgatgtg tccgtcgatg aagatcaccc
     3601 agaaccgggt tcattcaccg aaagggcgcg caacgctggt gcgtgaatgg ctgcgcttgt
     3661 tggcggatcg cggcgttgac ccactcaaac tggaacaaga actgcctgaa tccggcgtca
     3721 gtttacggac gttaattgcc cgcacgcgca atagctggca tgcgaataaa ggcgaatacg
     3781 acttctcaca cgaagtcaaa gaggctatgt cgggctgtct ggcctgtaaa gcgtgttcga
     3841 cccagtgccc catcaaaatt gatgtgccgg agtttcgctc tcgttttctg cagctctatc
     3901 acacccgtta tttacgcccg cttcgcgacc acctcgttgc tacggtcgag agctacgcac
     3961 cgctgatggc acgcgcgccg aaaaccttta acttctttat taaccagccg ctggtgcgca
     4021 aactctcgga aaaacatatc ggcatggttg atttgccact gctgtcagtc ccctcgctac
     4081 aacaacaaat ggtggggcat cgctcggcaa acatgacgct ggaacagctt gaagctctca
     4141 atgcagagca gaaagcgcgc acggtgttgg tggtgcagga cccctttacc agctattacg
     4201 atgcgcaagt ggtggcggat tttgtccgtc tggtcgaaaa attaggtttc cagcctgtgt
     4261 tactgccatt ttcgccaaat ggcaaagccc agcatatcaa aggctttctt aatcgttttg
     4321 cgaagacggc gaaaaagacg gcggatttcc tcaaccgtat ggcgaagctg gggatgccaa
     4381 tggtgggcgt cgatccggcg ctggtacttt gttatcgcga tgaatataaa ctggcgctgg
     4441 gcgaggaacg tggcgagttt aacgtattac tggcgaatga atggctggca agcgcacttg
     4501 actcacagcc agtggctaca gtcagcggtg aatcatggta tttctttggt cactgtaccg
     4561 aagttaccgc tttgccgggc gcgccagcac aatgggccgc gatatttgcc cgttttggcg
     4621 cgaaactgga aaatgtcagc gtgggttgct gcggcatggc agggacttac ggacatgaag
     4681 cgaaaaacca taaaaattcg ctcgggatct atgagttatc ctggcatcag gcgatgcagc
     4741 gactgccgcg taatcgctgt ctggcgaccg gatattcctg ccgtagccag gtaaaacggg
     4801 tcgaaggcac gggggtacgc catcctgtgc aggctttact ggagattatt aaatgatatg
     4861 gaaacgaaaa atcaccctgg aagcattgaa tgctatgggt gaaggaaaca tggtggggtt
     4921 gctggatatt cgctttgaac atattggtga tgacaccctt gaagcgacaa tgccagtaga
     4981 ctcccggaca aagcagcctt tcgggttgct gcatggaggc gcgtctgtgg tgctggccga
     5041 aagtatcggt tccgttgccg gttatttatg taccgaaggt gagcaaaagg tggttggtct
     5101 ggaaatcaat gctaaccacg tccgctcggc acgagaaggg cgggtgcgcg gcgtatgcaa
     5161 accgttgcat ctcggttcgc gtcaccaggt ctggcagatt gaaatcttcg atgagaaagg
     5221 gcgtttgtgc tgttcgtcac gattgacgac cgccattttg tgacgttgtc accagaaaag
     5281 tgtgacgcat attgcttttg gtcattatct gcacagtaaa cggtggtata ctgtgcaggt
     5341 cttgtctaaa agcgaggatg ctatgtctac tcaacttgat cccacccagc tggccattga
     5401 atttttacgc cgtgaccaga gcaatctttc acctgcccaa tatctcaaac gtctgaaaca
     5461 actagaactt gaatttgctg acctgcttac tctctcttct gctgaattaa aagaagaaat
     5521 ctactttgcc tggcgtctgg gcgtgcattg atcctgactt aatgccgcaa gttcgccata
     5581 tcgacctgga ttaatctccg tccaggttcg atggccttct taatactgct tatctacccg
     5641 cctgatattg ttcaaaaata atactaatcg cagtttgtgt taaaacggcg ggttagcttt
     5701 atgagattat tcttatcgcc ccttcaagag ctaagccact gagagtgccg gagataagcg
     5761 ccggatgggg tagaaaccct taagcctgtg tcgcacagac ttaagggttt tcttatttct
     5821 gaacgctgca cttttttacc tatctcttaa atagtcattt tcaatacaac tttttctttt
     5881 tcatcacagc cttaatgctc cttagataat aatcattatc taacaatgag atacctaatt
     5941 cttagcgtgc ctgttaaccc acacatcagg gtctatgctt attaaaagca ggaaaaaagc
     6001 atgttttacg gtaaagcccc tgcgtttgtt gggttgaact gataatcatt atcactaaca
     6061 tgctgttata cgctgaaagc gatgaagtga ggtaaatcga tggacatgca ttcaggaacc
     6121 tttaatccac aggatttcgc ctggcagggc ttaacgctga cacccgcagc cgctgtccac
     6181 atccgcgagc tggtggcaaa gcagccgggt atggtcggcg tgcgcttagg cgtgaagcaa
     6241 acgggctgcg cgggctttgg ctatgtgctc gatagtgtta gcgagccgga caaagacgat
     6301 ctgctgtttg aacacgacgg tgcgaagctg tttgtcccgc tgcaagcgat gccgtttatt
     6361 gatggcacgg aagtcgattt cgttcgtgaa ggacttaatc agatattcaa atttcacaac
     6421 cctaaagccc agaatgaatg tggctgtggc gaaagctttg gggtataggc ggtactatgt
     6481 ctcgtaatac tgaagcaact gacgatgtca aaacctggac cggcggcccg ctgaattata
     6541 aagaaggatt cttcacccag ttagccaccg atgagctggc aaaggggata aacgaagagg
     6601 tggtgcgcgc aatttcggcg aagcgtaatg agccggagtg gatgctggag tttcgtctca
     6661 acgcctatcg cgcatggctg gagatggaag aaccgcactg gttgaaagcg cactacgaca
     6721 agctgaatta tcaggattac agctactact cagcaccatc gtgcggtaat tgtgacgaca
     6781 actgcgcgtc tgaacccggc gcggtgcagc aaactggcgc gaacgccttt ttaagtaaag
     6841 aggtggaggc ggcgtttgag cagttgggcg ttcccgtgcg ggaaggcaaa gaggtggcgg
     6901 tggatgccat tttcgactct gtttcggttg ccaccactta tcgcgaaaaa ctggcggagc
     6961 agggaattat tttctgttcc tttggcgagg cgatccacga tcacccggaa ctggtgcgta
     7021 aatatctcgg caccgtggtg ccggggaatg acaacttctt tgccgcactt aatgcggcgg
     7081 tagcctctga cggtacgttt atttatgtgc ctaaaggcgt gcgctgcccg atggaacttt
     7141 ccacctattt tcgtattaac gcggaaaaaa ccgggcagtt tgagcgcacc attctggtgg
     7201 ccgacgaaga cagctacgtc agctacattg aaggctgttc cgctccggtg cgtgacagct
     7261 atcagttaca cgcggcggtg gtggaagtca tcatccataa aaacgccgag gtgaaatatt
     7321 ccacggtaca aaactggttc cctggtgata acaacaccgg cggtattctc aacttcgtca
     7381 ccaagcgtgc tttgtgcgaa ggcgaaaaca gcaaaatgtc atggacgcaa tcagaaaccg
     7441 ggtcagcgat tacgtggaaa tatcccagct gcattttgcg cggcgataac tccattggtg
     7501 agttttactc agtggcactg accagcggtc atcagcaagc ggataccggc accaagatga
     7561 tccacatcgg taaaaacacc aaatcgacca ttatctcgaa agggatctct gccggacata
     7621 gtcagaacag ttatcgcggc ttagtgaaaa tcatgccgac ggcaaccaat gcgcgcaatt
     7681 tcactcagtg cgactcaatg ctgattggcg ctaattgtgg ggcgcatacc ttcccgtatg
     7741 tcgaatgtcg caataacagc gcacaactgg agcacgaggc aacgacatca cgtattggtg
     7801 aagatcaact gttttactgc ctgcaacgcg ggatcagcga agaagacgcc atctcgatga
     7861 ttgttaacgg tttctgcaaa gacgtgttct cagaactgcc gctggaattt gccgttgaag
     7921 cacaaaaact cctcgccatc agtcttgaac acagcgtcgg ataaggaata aacatgttaa
     7981 gtattaaaga tttacacgtc agcgtggaag ataaagctat cctgcgtgga ttaagcctcg
     8041 acgttcgtcc cggcgaagtt cacgccatta tggggccaaa cggttctggc aaaagtacct
     8101 tatcggcaac gcttgccgga cgagaagatt atgaggtgac gggcggcacg gttgagttca
     8161 aaggcaaaga tttgcttgcg ctgtcgccgg aagatcgtgc aggtgaaggc atctttatgg
     8221 ccttccagta tccggtggaa attcccggcg tcagtaacca gtttttcctg caaacggcac
     8281 ttaatgcggt gcgcagctat cgcggccagg aaacgctcga ccgctttgat tttcaggatt
     8341 tgatggaaga gaaaatcgct ctcctgaaga tgccggagga tttattaacc cgttcggtaa
     8401 acgttggttt ttccggcggc gagaaaaagc gcaacgatat tttgcaaatg gcggtgctgg
     8461 aaccggagtt atgcattctt gatgagtcgg actccgggct ggatattgac gcattaaaag
     8521 tggttgccga tggcgtgaac tcgctgcgtg acggcaagcg ttcattcatc attgttacgc
     8581 actaccaacg cattctcgac tacatcaagc ctgattacgt ccatgtgctg tatcagggac
     8641 gaattgtgaa atccggtgat ttaacgttgg tcaaacaact ggaggagcag ggttatggct
     8701 ggcttaccga acagcagtaa cgcgctgcaa cagtggcatc atttgtttga agctgaaggg
     8761 gcgaaacgct ccccgcaagc acagcagcat ttacaacaat tgctgcgtac cggactgccg
     8821 acacgtaaac atgaaaactg gaaatatacg ccgctggaag ggctgaccaa tagccggttt
     8881 gtcagcattg cgggagagat atccccacag cagcgagatg ccttagcgtt aacgttagac
     8941 gccgtgcggc tggtgtttgt cgatggacgt tacgtgcctg cgctgagcga tgcaactgaa
     9001 ggcagcggat atgaagtgag cattaacgac gaccgtcagg ggttacccga cgctattcag
     9061 gcggaagtgt ttctgcattt gacggaaagc ctggcgcaaa gcgtgacgca tatcgccgtg
     9121 aagcgcggtc aacgaccggc aaagccattg ctgttaatgc atatcaccca gggcgtggca
     9181 ggtgaagagg tgaatactgc ccattaccga catcatctgg atctggcgga aggtgccgaa
     9241 gcaacggtga tcgaacattt tgtcagcctt aatgatgctc gtcacttcac cggcgcacgg
     9301 ttcactatca acgtcgcagc gaacgcccac ttgcagcata tcaagctggc gtttgaaaac
     9361 ccggtcagtc accactttgc ccataacgat ttgttgctgg ctgacgatgc caccgcattt
     9421 agccacagtt tcctgctggg tggcgcagtg ttacgacaca acaccagtac gcaactcaat
     9481 ggcgaaaaca gcacgctgcg gatcaatagc ctggcgatgc cggtgaaaaa cgaggtgtgt
     9541 gatacccgta cctggctgga acacaataaa ggtttttgta acagtcgaca gttgcataaa
     9601 actatcgtca gcgacaaagg ccgcgcggta tttaacggtt tgatcaacgt cgcgcagcac
     9661 gccatcaaaa cggatggtca gatgaccaac aataatctgc tgatgggaaa actggcggaa
     9721 gtggatacta aaccgcagtt ggaaatctat gcagatgatg tgaaatgcag ccacggcgcg
     9781 acggtggggc gtattgatga tgaacagatg ttctatctgc gctcgcgcgg gatcaatcag
     9841 caggatgccc agcagatgat catttacgcc tttgctgccg aactgacgga agcactgcgt
     9901 gatgaagggc ttaaacagca ggtgctggcc cgaatcggtc aacggctgcc aggaggtgca
     9961 agatgacttt ttccgttgat aaggtgcggg ccgatttccc ggtgctttcg cgtgaggtga
    10021 acagtttgcc gctagcttat ctcgacagcg ccgccagtgc gcagaaaccg agccaggtga
    10081 ttgatgccga ggctgagttt tatcgtcatg gctacgcggc ggtgcatcgc ggtattcata
    10141 ccttaagcgc ccaggcgacc gagaaaatgg agaacgtgcg caagcgtgct tcgctgttta
    10201 tcaatgcccg ttccgcggaa gaattggtgt ttgtccgcgg caccacggaa ggcattaacc
    10261 tggtcgccaa tagctgggga aacagcaacg tgcggtcagg cgataacatc atcatcagtc
    10321 agatggagca ccacgctaac attgtcccct ggcagatgct ttgtgcacgc gttggcgcag
    10381 agctgcgtgt gatccctctc aaccccgacg gtacgctgca actggagatg ctacctaatc
    10441 tgttcgatga gaaaactcgc ctgctggcaa ttactcatgt ctccaacgtg ctgggaacgg
    10501 aaaatccgct ggcggaaatg atcacacttg cgcatcaaca tggcgcaaaa gtgctggtgg
    10561 atggcgctca ggcggtgatg catcatccgg tggatgttca ggcgctggat tgcgattttt
    10621 acgtgttttc cgggcataaa ctgtatggcc ctaccggaat tggcattctt tatgtcaaag
    10681 aagccttgtt gcaggagatg ccgccgtggg aagggggcgg ttctatgatc gccaccgtca
    10741 gcctgagtga aggcactacc tggaccaaag caccatggcg gtttgaagcc ggtacaccca
    10801 ataccggggg catcattggt cttggcgcgg cgctggagta tgtgtcggcg ctggggctta
    10861 ataacatagc cgagtatgaa cagaatctga tgcactacgc gctagcacag ctggagtctg
    10921 taccggatct cactctctat ggcccacaga acaggcttgg cgttattgct tttaatctcg
    10981 gtaaacacca cgcctatgat gttggcagtt ttctcgataa ctacggcatt gctgtgcgta
    11041 ccggacatca ctgcgcaatg ccattgatgg cctattacaa cgttcctgct atgtgtcggg
    11101 cgtcgctggc catgtataac acccatgaag aagtggatcg tctggtgacc ggcctgcaac
    11161 gtattcaccg tttgctggga taacagggag gcactatggc tttattgccg gataaagaaa
    11221 aattgctgcg taatttttta cgctgcgcca actgggaaga gaaatatctc tacattattg
    11281 agctgggcca gcgtctgcca gaattacgcg acgaagaccg aagcccacaa aatagcattc
    11341 agggctgcca gagtcaggtg tggattgtca tgcgccagaa tgcgcaggga attattgaat
    11401 tgcagggtga cagcgatgcg gcgattgtga aagggcttat tgcggtcgtc tttattctct
    11461 acgatcagat gacgccgcag gatattgtca atttcgatgt gcgtccgtgg tttgaaaaaa
    11521 tggcgctcac ccaacatctc accccatctc gttcacaagg tctggaagcg atgattcgcg
    11581 caattcgcgc caaagccgct gcacttagct aaactaaagg gacagctttc atccggttgg
    11641 ctcacattgc cggatggtca atgtttacac tgacctgcac aggagtgttt tggtttcagg
    11701 tgaacataag caccatccga cgtttcagcg tgagtctccg gcaaatacag gaggtttaca
    11761 atgaaacgcg cgtctttgct tacactcacg cttatcggcg cttttagcgc catccaggca
    11821 gcctgggcgg ttgattatcc gctacctcca accggaagcc gactggttgg gcaaaatcaa
    11881 acgtatacgg tgcaagaagg ggataaaaac cttcaggcca tcgcccgacg ttttgatact
    11941 gcggcaatgt tgatccttga agctaataac actatcgctc cggtgccaaa acccggtacg
    12001 acgataacta ttccttcgca actgttatta cctgatgcgc cgcgtcaggg gattatcgtt
    12061 aaccttgcag agctgcgcct ttattattat ccgccgggag aaaatatcgt gcaggtttat
    12121 ccgattggta ttggtttgca ggggctggaa acgccggtga tggaaacgcg tgtggggcag
    12181 aaaatcccta acccaacctg gacgcctacg gcgggcattc gtcagcgttc gctggagcgt
    12241 ggcattaaat taccgccagt cgttcctgcc gggccaaata acccactagg acgttacgca
    12301 ctgcgcctcg cgcatggtaa tggcgaatac ctcattcatg gcaccagtgc gccggacagc
    12361 gtcggtttgc gcgtcagttc gggctgtatt cgcatgaatg cgccggatat taaagcctta
    12421 ttctccagcg tgcggacggg aacgccggtg aaagtgatca acgaaccggt gaaatattcc
    12481 gtggaaccga acgggatgcg ttatgttgaa gtacatcgac cactatcagc agaagaacag
    12541 cagaacgttc agacaatgcc atacacgctg ccagcaggct ttacgcaatt taaagacaat
    12601 aaggctgtag atcagaagtt agtcgataaa gcgttgtatc gtcgggcagg gtatccggtt
    12661 gcggtgagca gtggagcaac tcccgcagcc agcaatacgc cttcagtaga gtcagcgcag
    12721 aatggtgaac cagagcaagg gaatatgtta cgcgcgacgc agtagcggta aatggcaggc
    12781 aaaaaaaatg gcgcacaatg tgcgccattt ttcacttcac aggtactatt acttgcggta
    12841 tttagtagcc atgttgtcca gacgctggtt agcacgagct gcgtcatctt tagcagcctg
    12901 aacgtcggaa cgcattgcgt tcacgtcgtt gctcagctgg tcaactttag cgttcagagt
    12961 ctgaacgtca gaagacagct gatcgatttt agcgttgctg gagcaacctg ccagcagagt
    13021 agaacccagg attaccgcgc ccagtaccag tttagtagct ttcattatta ataccctcta
    13081 gattgagtta atctccatgt agcgttacaa gtattacaca aagtttttta tgttgagaat
    13141 atttttttga tgggaaggca cttatttttg atcgttcgct caaagaagca tcgaacgctg
    13201 ggttttagat aaaaaaattg agagaaaaca ggatgcttcc atcggattca tcttagataa
    13261 agtgagatta tatagtgaaa tccgatttga ttttttattg cttctggtta tcgattaaat
    13321 aaaaaaagcg cccatcaggg cgcttcgata tacaaattaa ttcacaaaag caatattaca
    13381 ggacgtgaac agatgcggtg ttagtagtgc cgctcggtac cagtgcacca gaaaccataa
    13441 ctacgacgtc gcctttgtgt gccagaccgc tctgcagagc cagttcttta cccagacggt
    13501 agaaatcatc agtagaagtg atctctttaa ccagctgcgg cacaacgcct ttgctcagta
    13561 ccaactgatg agccgttttt tcgttggtgg tcagtgccag gatggtggca tccgggaagt
    13621 atttacgtac tgcgcgagca gatttaccgc cctgggtagc aaccacgatc agcggagcat
    13681 ccagtttttc agcagtttca acggcaccac ggcataccgc ttcggtaatg cgcagtttac
    13741 ggttgtcatt gttgaactcg agacggctgt tcatcacgcg gtcggtacgt tcgcagatgg
    13801 tcgccatgat agaaaccgct tccagcgggt atttaccttt tgcggattca ccagacagca
    13861 tcactgcgtc agtaccgtcg aggatggcgt ttgcaacgtc accggcttct gcgcgagtcg
    13921 ggcgtgggtt tttgatcatg gaatccagca tctgggtcgc agtgataacg actttacgtg
    13981 cacggataca tttttcgatc atcatcttct gggcgaagat aacttcttct accgggattt
    14041 ctacacccag gtcgccacgc gcaaccatga tgccgtcaga ggcttcgagg atttcgtcga
    14101 agttgttgag gccttcctgg ttttcgattt tggagatgat gtggatgttt tcgccgccgt
    14161 gcgctttcag gtgctcacgg atttcgataa cgtcagaacg cttacgaata aaggaagcag
    14221 cgacaaagtc tacgccttgt tcgcaaccaa agatcaggtc ctgtttgtct ttttcagcca
    14281 gtgctggcag ggcaatggaa acgccaggca ggttcacacc tttgttttca cccaggtcgc
    14341 cgttgttcag cactttacag ataactttgt taccttcaat ggcagtaact tccataccga
    14401 tcagaccatc gtcaaccagt acggtgttgc caacagacag gtcagttgtg aaaccttcat
    14461 acgttaccgc aaccatttcg ctgttgccga taacagattt atcagtagtg aaagtaaagg
    14521 tctgacccgc tttcagagaa acgtcgttac cgccttccag tttcatggtg cggatttccg
    14581 gacctttggt atcaagcagg atagcggcgg ttttaccagt tttgctcatc acgttgcgca
    14641 gattctgaat gcgctgaccg tgttctgcat agtcaccatg agagaagttc agacgcataa
    14701 cgttcatgcc agcgtccagc attttagcta acatctcttc agattcggtt ttcggtccga
    14761 tggtgcaaac aattttggtc tttttcatga cagtcttagt ctttaagttg agaaggatgg
    14821 gagaaacttg ctttctgggc gcactgccgg aaagcgaatc cggtattacg aaagtggtgg
    14881 tgcctcgctc taaggatagg tgacatcgaa aaagcgtgca gaggaatgtg tgcttgtgtc
    14941 tcagcccaac gtgagtgcct gtttttgagt cgttgagttc tacagtccaa agtgctgaaa
    15001 ccattcaaga gtcaattggc gcgcattata cgctgaaatt aatccaaaag gaaaacaaaa
    15061 acagcgtttc aaaaaatata caacttgtta gacaataaat tgttatcaaa gatttaacgt
    15121 tccagggaaa aggttacgca aaaacttcgc tgtttgcgca acgtctggtg ccggggttgt
    15181 cactgtgaag ataagtgaaa gttcatccgg tgtataaata catcatcgct caattgctac
    15241 agttaaaata atttatcgcg ttatttgtct gattttgttt gatttttgtc taattggtta
    15301 gattgatata tgctgatagt tggcatgata aataggtata aagaatggga aatcggacaa
    15361 aagaggatga actgtaccga gaaatgtgca gagttgtcgg taaagttgtg ctggaaatgc
    15421 gcgatctggg gcaggaacca aagcatattg ttatcgcagg cgtattacgt acagcattag
    15481 ccaataaacg cattcagcgc agtgagctgg aaaagcaggc gatggaaacc gtcattaacg
    15541 cactggtaaa atgaccattc aggatgaggc gataagcttc atcctgatat tcttgcttca
    15601 gttgcggtcg agttaatcat tctaaataac aactgctgaa attaaacgaa tttcgatatg
    15661 tgttttaatt tataacgata atattatttt tgttttctgc aatgaccgtc acaaataatt
    15721 gtcgcttaag ttaaatttat ttcaaatgat aataaatatc agttcactta taatttcttg
    15781 ctttgtaatt ttaattgata acgatcaatg ttaagggctc agaataatca cattattttt
    15841 tctcctaacc ataaaggatt agtttatcgg cgttaaatct tttctcatac actatcaggt
    15901 tagggaaaat atctggtgtt gaggacagag tcagcagcgt attagttgaa tgcttaatat
    15961 caatctgctg aattgtcagc actgtgtttg cgaagaggat gcgaaataaa tgaacccggt
    16021 tgatcgtcca ctattagata ttggcttaac gcgattagaa ttcttgcgta tatcaggaaa
    16081 aggccttgct ggtttaacaa ttgcccctgc gttactgtca cttttgggtt gcaaacagga
    16141 agatattgat agcggcacag tagggttgat aaatacaccc aaaggagtgc tggtgaccca
    16201 acgtgctcga tgcacgggtt gccaccgctg tgaaatctct tgtaccaact tcaacgatgg
    16261 ctcagtaggg acattcttct cccgtatcaa aatccatcgc aattatttct ttggcgataa
    16321 cggggttggc tctggtggcg gcctgtatgg cgatctcaac tatactgcgg acacctgccg
    16381 tcaatgcaaa gaaccgcaat gcatgaatgt ctgcccgatt ggtgcgatta cctggcaaca
    16441 ggaagaaggc tgtattaccg tcgatcataa acgttgtatt ggctgtagcg cctgtacgac
    16501 ggcgtgcccg tggatgatgg ccaccgtaaa taccgaaagt aaaaaatcct cgaaatgtgt
    16561 gttatgcggt gaatgcgcaa acgcctgccc aacaggggcg ttaaaaatta tcgagtggaa
    16621 agatattact gtgtgaatct tgcaaaggaa aaaatcatgg ctaacggttg gacaggtaat
    16681 atattaagag tcaatctcac gacaggaaat attaccctcg aagattccag taagtttaaa
    16741 agttttgtcg gtggtatggg cttcggctac aaaattatgt atgacgaagt accgccaggc
    16801 acgaaacctt tcgatgaagc gaataaatta gtctttgcta ccggcccatt aactggatct
    16861 ggtgccccct gtagttctcg tgtaaatatc acctcacttt ctacttttac caaaggaaat
    16921 ttagtcgtcg atgcccatat gggtggcttt tttgcagcgc aaatgaaatt cgctggctac
    16981 gacgtcatta ttatcgaagg gaaagcgaaa tcaccggtat ggctgaagat taaagatgac
    17041 aaagttagcc tggaaaaagc cgatttctta tggggaaaag ggacgcgcgc aacgacggaa
    17101 gaaatttgtc gcttgaccag tccggaaacc tgtgtggcgg ctattggtca ggctggggaa
    17161 aaccttgttc ctctctctgg catgttgaat agccgtaacc acagcggtgg tgcgggaact
    17221 ggcgcaataa tgggttcgaa aaacctgaaa gcgattgcgg ttgaagggac gaaaggggtc
    17281 aacattgccg atcgtcagga gatgaagcgt ctcaacgatt acatgatgac tgaacttatc
    17341 ggtgcgaata acaaccatgt cgtgccaagt acgccgcaat cgtgggcaga gtattcagat
    17401 cccaagtcac gttggacagc acgtaaaggg ctgttttggg gcgcggctga aggtggtccg
    17461 attgaaacgg gtgagattcc gccaggcaat cagaacacgg tcggctttcg tgcctataaa
    17521 tccgtttttg acttaggtcc ggcggcagag aaatacacag taaaaatgag cggctgccac
    17581 tcttgcccga tccgttgtat gacccaaatg aatattcctc gggtgaaaga gtttggcgtg
    17641 cctggcaccg gtggtaacac ttgtgtagca aactttgtcc ataccactat cttcccaaac
    17701 gggccgaaag attttgaaga taaagacgat ggtcgtgtga ttggtaacct ggttggtctg
    17761 aatctgttcg atgactacgg cctatggtgt aactatggtc agcttcatcg cgactttacc
    17821 tattgttaca gcaaaggggt gttcaagcgt gttctgcctg ctgaagagta tgcggaaatt
    17881 cgctgggatc aactggaagc gggtgacgtt aacttcatta aagattttta ctaccgtctg
    17941 gcgcatcgtg tgggtgagct gagtcacctg gctgatggtt catatgccat cgcagaacgc
    18001 tggaatttgg gtgaagagta ctggggctac gcgaaaaata aactctggtc gccgtttggc
    18061 tatccggttc accatgccaa tgaagcgtca gcgcaggtcg gttccattgt taactgtatg
    18121 ttcaaccgtg actgcatgac gcatacccat atcaacttta ttggttccgg cttgccattg
    18181 aaactgcaac gtgaagtggc gaaagaactt tttggttctg aagatgctta cgacgaaacc
    18241 aaaaactaca cgccaatcaa tgacgcaaaa attaaatatg ctaagtggtc gctgctgagg
    18301 gtctgtttgc ataacgccgt caccctgtgc aactgggtct ggccaatgac cgtttcgccg
    18361 ctgaaaagcc gtaattatcg gggcgatctg gcgcttgaag ccaaattctt catagcgatc
    18421 actggcgaag atatgactca ggaaaaatta gatttagctg cagagcgtat ctttacgttg
    18481 catcgcgcct acacggtaaa actgatgcaa accaaagata tgcgtaatga acacgatctt
    18541 atctgttcct gggtattcga caaggatccg cagatcccgg tctttactga aggtactgac
    18601 aaaatggatc gtgacgatat gcatgcttcg ctcacgatgt tctacaaaga aatgggctgg
    18661 gacccacagc ttggttgtcc gacccgcgaa acattgcagc gtctggggct ggaagatatt
    18721 gccgccgatc tggcagcaca caatctactg cctgcgtaag gaatgggtga gatgaaccat
    18781 aaggatgaat tgccgttagc ggaagtcagc gaaattgacg aggcgaagcg gcaatggttg
    18841 caggggatgc gtcaccccgt tgatacggta accgaaccag aacctgctga aatcctggca
    18901 gagttcattc gccagcattc tgcggctggg cagctggtgg cgcgcgccgt gtttctctcg
    18961 ccgccctatt cggttgcaga agaggaactg tcagttttgc tggaaaacat taagcagaac
    19021 ggagactacg cggatatcgc gtgtatgacg ggaagccagg atgattacta ttactcaacg
    19081 caggccatga gtgaaaacta cgcggcgatg tctttgcaag ttgtggagca ggacatttgt
    19141 cgcgctattg cacacgccgt tcgttttgag tgccagacgt atcctcgtcc ttacaaagtc
    19201 gccatgctga tgcaagcgcc atattacttc caggaagcgc agattgaagc cgcgatcgcc
    19261 gcgatggatg ttgcacctga atatgccgat atacggcagg tggagtcatc gacggcggtg
    19321 ttgtacttgt ttagcgagcg atttatgacc tatggcaagg cgtatggctt atgcgaatgg
    19381 ttcgaggtag agcagtttca gaacccctga aatttcaggg agatgtcatg gatagggtgg
    19441 acagttgcag ccactgcatt aggggataat cagatgtcct tcactcgacg caaatttgtt
    19501 ctggggatgg gaacagtaat cttttttact ggttctgcgt cttctctgtt agcgaacacg
    19561 aggcaagaaa agaaagttcg gtatgccatg attcatgacg agtcacggtg caatggctgt
    19621 aatatttgcg cccgcgcatg ccgtaaaacc aatcacgtcc ccgctcaggg aagccgttta
    19681 tcgatagcac acattccagt caccgataac gacaacgaaa cgcagtatca cttttttcgc
    19741 cagtcatgtc agcactgcga agatgctccg tgcatcgacg tttgtccgac agcggcatcg
    19801 tggcgtgatg agcaggggat cgtacgggta gaaaaatcgc agtgcatcgg ctgcagttat
    19861 tgcattggcg cttgtcctta ccaggttcgc taccttaacc ctgtcactaa agtggcagat
    19921 aaatgtgatt tctgcgctga gtcccgactg gcaaaaggct ttccgcccat ttgcgtcagc
    19981 gcctgcccgg aacacgcctt gatctttggt cgcgaagata gcccagaaat tcaggcgtgg
    20041 ttgcaggaaa ataaatacta tcaatatcag ctacctggtg ccgggaaacc gcacctgtat
    20101 cgccggttag gtcaacattt gattaaaaag gaaaatgtat gaacccgtcg caacatgctg
    20161 aacagtttca gaaccagttg gcgaactatg tgccacagtt cactccccaa ttttggccgg
    20221 tgtggttgat cattgccgga ctattgctgg tagggatgtg gttggtgctg gggctgcatg
    20281 ccttgcttcg tgctcgtggc gtgaagaaat cagccaccga ccatggtgag aaggtttatc
    20341 tttacagcaa agcggtcaga ttatggcact ggtcgaatgc gttactcttt gtattgttgc
    20401 tggcaagtgg gctgataaat cactttgcgc tggtgggcgc aactgcggtt aaaagtctgg
    20461 ttgcggtgca tgaagtttgc ggatttttgt tactggcatg ctggctcggc tttgttctga
    20521 tcaatgccgt tgggggtaat ggtcaccact atcgcattcg tcgtcagggg tggctggagc
    20581 gagcggcaaa acaaacgcga ttctatttgt ttggcattat gcagggggaa gaacatcctt
    20641 tcccggcaac aacccagtct aaatttaatc ccttacagca ggtcgcctat cttggtgtca
    20701 tgtatggatt gctgccgttg ttactattga cggggctgct gtgtctctat ccgcaagccg
    20761 tgggagatat gtttcctggc gtaagatact ggttattgca ggcgcatttt gctctggcat
    20821 ttataagcct cttttttatc ttcggtcatc tttatctttg caccacgggg cgtacgccac
    20881 acgaaacctt taaaagcatg gtcgatggct atcaccggca ctaacgaatg atcattacac
    20941 gagcagacct gcgagaatgg cgtatcggag cggtgatgta tcgctggttc ctgcgccatt
    21001 tcccacgcgg cggtagttat gccgatattc atcatgcact gattgaggaa ggatatacgg
    21061 actgggcgga gagtctggtt gagtatgcgt ggaaaaaatg gctggcggat gaaaacttcg
    21121 cgcatcagga agtttcttct atgcaaaaac tggccacaca tcccggagag agaccatttt
    21181 gcagtcagtt tgcccgcagc gacgatcatg ctcgcatcgg ctgttgtgag gataatgcca
    21241 gaatcgcaac tgctgggtat gccgcgcaaa ttgccagtat gggttatagc gtgcggattg
    21301 gaagtgtcgg ctttaacagt cacattggca gctccggtga acgcgcacgg gttgctgtaa
    21361 ccggcaattc ttcgcggata agcagcgctg gagatagcag taggattgcg aataccggaa
    21421 tgcgagtacg cgtttgtaca ttgggtgaac gatgtcatgt cgccagtaat ggtgacctgg
    21481 tgcaaatcgc cagctttggc gcaaacgcca gaattgccaa cagcggcgac aatgtacaca
    21541 tcattgccag cggtgaaaat tcaacggtag tgagcacggg cgtggtcgac tcaattattc
    21601 tcgggccagg aggaagcgcc gcactggcat atcatgacgg tgaaagagtt cgcttcgccg
    21661 tcgccattga aggtgaaaac aatattcgag ccggagtccg ctatcgtctt aatgaacagc
    21721 atcagtttgt tgagtgctga tagctttacc tttaatcaaa cgaaagacgt ttacgtgcac
    21781 gggaggcagg ttttacgaca gcccgagcca tcgcctcacc aatttctgca catgccgtaa
    21841 gcccctgaac gaaaggctgg tcgtgcatta accagggcaa cgcgccgaac gctacgcgcc
    21901 cacgaatttc ttcgggttgc tgtagcgtat aatcttcgcc aacatcaggg atttcatccc
    21961 ctgttttctg taattgttcg cgtagtccag ggaaaggaat atctttcact ttaagcggac
    22021 gctgcccgcg ggcatcaata aaaacgtcaa acgagtagct attgtcttcc gttttcagga
    22081 cggtgcgcga ctcattaatt tccatttcgt agtcttcacc gagggcgagt atatgaatga
    22141 ttcccgcttc acgtaaggcc agcagccgac gaatagactc tgaagggatt gcggcataat
    22201 tatctatgaa aactcgggca aggcctttac tgaaccgttt atggtcgtgt tcattcagat
    22261 gtggaacaat ttcctgtaca gcttcatgca ggcgcagaat gacataacgc cagggaacag
    22321 tatgtttttc tcgtttattg cgttcgactt cctggagatt tttttctgcc cagtcaaatg
    22381 gggcgcgttg tttgcgctcg gcaaaccagg cttgagcaaa ggaatcgaca ttcaggctct
    22441 ctaaggctat gcgttggctc cagcctggat cagcaaactt gatttcctct actatcaatc
    22501 taaatacccg atccaaaagg ccatattcgc ctttttgaat ctcagcattt aatgcctgat
    22561 cagtgacggt gtgtaagggc tcgtagggaa tagggcaata gaaatcggct tcgggtaaaa
    22621 tacccgtgcg cgacattaac gtaatattta gcttttcact tgcgttatcg cggtgaaaaa
    22681 cgacgtgttg tttatcatct tcaatgaacg aaccatgctg aatagccact gccattgccg
    22741 catccagtcc gctcaaggat gttcccataa tacccacgtt acacgcatcg acctttgctt
    22801 ccatcaggcc tgaccacggg ctgggaaaat acgttctggt tgcttcttct tcatcaggcc
    22861 agacgtgacc cgtggcaatc accgctaaat caaacgtctc gctgggtaaa tcctgatttg
    22921 tagcgatcat gacgccagca tttgtaattt gcagatcggt aacctggcat gattcataaa
    22981 cagccactgc aaatttttgc tgtcgtgcct ggtctactaa tcgtaaaaat tgatcgcgga
    23041 aatattcgcc cagcagaatt cgcggtaaaa actgacgatc gtgcaaagtt tcttttttaa
    23101 cgccataacg ttggagatgg ctggcttctt gcttttgtag ccattcgaga tacgtacaat
    23161 aaatcggcgg tatttcaata ctggcaatat ttgccagcat cagttttgag ttttcctcat
    23221 cactgtatgg catcccgaca ccggcttcat cagcctgctc gaagatagaa atagaaagtg
    23281 gcgtttgttg ctgtagaagc gagaataagg tgtagatccc cgtaggcccg gcacccacaa
    23341 tagcaatttt tttcattgtt acttacctgt acgcattctt tcgaatttag tgttatcaga
    23401 taagtttggt tgagattttt agaatttgag aaatttcaga cagggatgaa aagggcgcta
    23461 accgcccttg attaaattct gtcaggcgag ttttgcctga ttgatttgac tcagtggctc
    23521 attgacatcg aaaactttgg cgacaacttc ctcaacgccg agatttttca gtcgggcagt
    23581 atgtttttcc agataggcaa gggcgctttt ttcatcagta aaaaggtaga tcccaccggc
    23641 ttcgtggttc ttttcacttt ctgtccatac cttccacaga aaaccaggtt cctgattaat
    23701 cgactcagca agcggtttaa gctgctcagc cattgcgtcg ccaaatgggc cattgaaaga
    23761 aaaatgaagt tgtaacaaag ttgccatagc gattctcctt ctgataacgc atacgaagac
    23821 agtgtaaatc ttttaacgta ttggatacag agaagaaaca gagggaaaaa aggagaagac
    23881 cagattaaga aaatctggtg cgtccgagtg gactcgaacc accgaccccc accatgtcaa
    23941 ggtggtgctc taaccaactg agctacggac gcaggatggt gcgttcaatt ggactcgaac
    24001 caacgacccc caccatgtca aggtggtgct ctaaccaact gagctatgaa cgcaacgttg
    24061 taggtgacaa cggggacgaa tattagcggc agagtgggaa ggtggcaaga ggcaaaacgt
    24121 aattttctgc gctatttcga ccgtttgcag agcttttaag caaattggct atattttgtt
    24181 gatttgcaag ggcgattttt attcaggatc gcatttacat ctgatacaac ccaataatcc
    24241 gtgtatcaga gtttaaacag agttgtttgc caccatctca aatctgtcgt ggataaatcc
    24301 ttcgtagcct ttacacttag gtagcaataa aggcacacag atgcagcaaa ggaataaatc
    24361 atgggatctg atgcgaaaaa cttgatgagc gacgggaacg tgcaaattgt taagaccggc
    24421 gaggtcattg gcgcgacgca acttactgaa ggcgagttaa ttgttgaggc tggcggaaga
    24481 gccgaaaata ccgtggtcac gggggctggc tggttgaaag tggcaaccgg tgggatcgcc
    24541 aaatgcacac agtacggcaa caatggcacg ctatcggtca gcgacggtgc cattgccaca
    24601 gatattgttc agtccgaggg aggcgcaatt agtctctcta cgctcgctac ggttaatggc
    24661 cgccatcccg aaggtgaatt cagcgttgat aaaggttatg cctgcggttt gttgctggaa
    24721 aatggcggta acctgcgtgt actggaaggc catcgcgcgg aaaaaattat tctcgatcaa
    24781 gagggtggcc tgttggtcaa tgggacaacc tcagcggtcg tggtagatga aggtggtgaa
    24841 ttgttggtgt atccaggtgg ggaagccagc aattgtgaga ttaatcaggg cggcgttttt
    24901 atgctggcgg ggaaagccaa tgatacgttg cttgctggtg gcaccatgaa taatctcggt
    24961 ggtgaagact ctgacactat tgttgagaat ggagccatct atcgtctggg gacggatggt
    25021 cttcagctct acagttccgg taagacgcaa aacctgtccg ttaatgtggg tggtcgggct
    25081 gaagtgcatg ctggtacgct ggaaaacgcg gtaatacaag gtgggacagt gatcctgttg
    25141 tcacccacca gcgcggacga aaattttgtc gtagaggaag atcgcgcacc ggttgaactg
    25201 accggtagtg ttgcattact ggacggcgct tcaatgatta ttggctatgg cgcagatctg
    25261 caacaatcaa cgattactgt acagcagggc ggtgtattga ttctcgacgg cagtacggta
    25321 aaaggtgaca gtgtcacttt cagtgttggt aacatcaatc tcaatggcgg aaaactgtgg
    25381 ctaatcactg gtgcggcaac gcatgtgcaa ctgaaagtga aacgcctgcg cggagaggga
    25441 gcgatttgcc tgcaaaccag tgcgaaagaa atttcacctg acttcatcaa tgtgaaaggg
    25501 gaagttactg gtgatataca cgttgagata acagatgcca gtcggcaaac tctgtgtaac
    25561 gcactgaaac tacagccaga cgaagacggg attggcgcaa cgctccagcc tgcgtaaaaa
    25621 cacaggcgca acccgtgaag gttgcgcctt gtctttacta gcgagctgct cgttgcagaa
    25681 tgatggctga cggcagacgt tgcaggaacc gcatacgcag catcatcata atggctgccg
    25741 aagtcaggcc aataataaag cctatccaga agcctgctgg ccccataggt tcaacgacca
    25801 gatcggtcag tgccagaata tagccgcttg gcaagcccag cacccagtaa gccgtaaagg
    25861 tgatatagaa aatggaacgt gtatctttat aaccacgcaa aatcccactg ccaatcacct
    25921 ggatagagtc agaaatctga tataccgccg ccagcagcat caaatgcgca gccagcgtta
    25981 caacctcggg attgtcgttg tacaacaggg cgatttgctc tcgcagtgaa accgtgaata
    26041 tggccgtcag ggttgccata cagacaccca ccataagccc ggtccgcgca gcggtttgcg
    26101 catccagcgt tgagccttga cccagacgat aacctacgcg gatagttacc gctgccgcca
    26161 gcgacatggg aagcacgaac atcagtgaac taaagttcag ggcaatctga tgtcctgcga
    26221 catcaacaat accgagcgga gacactaaca gagccacgac ggcaaacagc gttacttcaa
    26281 agaacagtgc cagcgcaatt ggcaaaccga gttgaatcag tcgtttcata accgcaggat
    26341 cgggcttcgc ggtgcctttt tcgttacgaa tatcgcgcat cgagcgggcg cgtttaatgt
    26401 aagaaaccat ggcaaggaac atgacccaat acaccgccgc agtagccacg ccacaaccaa
    26461 cgccaccgag ctcaggcata ccgaaatgac cataaataaa gatatagttc accggaatgt
    26521 tcaccagcag gccgataaag cccatcacca tacccggctt ggtttttgcc agaccttcac
    26581 actggttacg ggcaacctgg aagaaaagat agcccggcgc gccccatagc aacgcacgca
    26641 gataacccac ggctttgtcc gccagagccg gatcgatgtt ttccatggag cggataatgt
    26701 agcctgcatt ccacagcacc agcataatga gaacggaaac aaaacctgcc agccagaaac
    26761 cttgtcgcac ctgatgcgca atgcgctcac gtcgaccgga gccatttaat tgcgcgataa
    26821 ccggcgttaa tgccagcagc agtccgtgac caaagaggat cgccggaagc cagatagaag
    26881 ttccgatagc gaccgccgcc atgtcggtgg cactatagcc gcccgccatc acggtatcga
    26941 caaaacccat cgcagtttgg gcgatttgcg cgagaatcac cgggattgct aatgctaata
    27001 acagacgcgc ttcactgata tacttctgca cgtgaacacc ttttatttgt agttatatga
    27061 gagactaaaa agccgcctga atgggcagca aaaagaagaa gcaggggaaa ttcagtctat
    27121 tgtagcgagg atttattaat tctccagtga aaaaatagcc attcttaccc cttcactggt
    27181 aagggcgttt tccacctgct attgtgctga acagaatgtc ttaactgatt tcaggagttg
    27241 taagtatgtt tacggggatt gtacagggca ccgcaaaact ggtgtcgatt gacgagaaac
    27301 caaattttcg cacgcatgtg gtggagttac ccgaccacat gctggacggt ctggaaaccg
    27361 gtgcttccgt ggcgcataac ggttgctgcc tgaccgtgac ggaaattaac ggcaaccatg
    27421 tcagttttga cctgatgaaa gaaacgttac gcattactaa tcttggcgat ttaaaagtgg
    27481 gggattgggt aaacgttgag cgtgcggcga aattcagcga tgaaattggc ggacacttaa
    27541 tgtcaggtca tattatgacc accgctgaag tagcgaaaat attaacctcg gaaaataatc
    27601 gtcagatctg gtttaaagtc caggatagtc agttgatgaa atatatcctg tacaaaggat
    27661 ttattggcat cgacggtatt agcctgaccg tcggcgaagt cacgccaacg cgtttttgcg
    27721 tccatttaat tccggaaaca ctggaacgca cgactcttgg gaagaaaaaa cttggcgcac
    27781 gcgtcaacat tgaaatcgat ccacaaactc aggcagtggt tgatacggta gaacgtgtgc
    27841 tggcggcacg agaaaatgcc atgaatcaac caggtacaga agcctgatct gaaatcgccc
    27901 ccggagcggg ggcgatagaa tagcctctag cgagcgactc gaaggccgtt ttcgactccg
    27961 cgagagaaca ccacctgcca gagctgaata tcacgggcgc ggaaagcacc tgcacaggca
    28021 ttcagataat aggtaaacat ccgtttaaag cgttcactgt agttatccgc aatttctggc
    28081 catgcggcga ggaaacgttc ataccacgcc atcaacgtag tatcgtaatc agcaccgaag
    28141 ttatgccagt cttccatcac aaagtggggt tcgctggact gagcaatctg gcgtacagag
    28201 ggcaggcaac cgttcggaaa aatatattta ttaatccagg gatcaacatt cagatcggtt
    28261 tttttcgaac cgatggtatg gagcaggaat ataccttccg gtttcaaatt acgatccacc
    28321 accgcaaaat aggtatcgta atttttcggt ccgacgtgtt cgaacatccc cacagaaaca
    28381 atacggtcaa actggtcgtt caggtcacga taatcttgca gcaaaatggt gacatccagg
    28441 ccttcacagc gttcctgagc cattttttgc tgttcggcag aaatggttac gccgaccacg
    28501 cttacgtcat aattagacgc catgtagtgc gccagtccgc cccagccaca gccaatatcc
    28561 agtacgcgca tccctggttt taactgcaat ttttcacaaa tcattttgag cttcgcctgc
    28621 tgggcagatt ccagattatc ggcatctttc cagtaagcac aggaatattg catgaaggga
    28681 tcaagcatgc ggctgaacaa gtcattaccc aaatcgtaat gctctttgcc gactatccag
    28741 gcacgttttt tactctgcag attgaagaga cgagcgccgg caatacgcag cgtgtctttg
    28801 aaatgatggg ggagttggtt ctcgagacct gcgcgtaaga ctttgctaaa aaacatatcc
    28861 agtcggtcac attcccacca gccatccata taactttcgc ctaaccccaa cgatccttcc
    28921 tgcaaaacgc gtttaaaaaa atcggggttt ttgacacgaa tatccgccgg ggcagaaccg
    28981 ttaatggcta taccggcacg gctaagtaat tcgttggcga tacggtacca gttgtcatcc
    29041 ggtacactga cttcttctat acacgatgaa ctcatagttt ctccatcact ggtcggtgat
    29101 cagaacctta aaacagcgta gacgcttttt gggctttgtg agaaatctcg cagaaaaaac
    29161 cgcgagtcta taatccgacg tagaacagag ggaaaggagg aacccttgcc gaaatgacca
    29221 tccatagtga gtcgggaacg atcctgtccc cgtaaaaaca taatatttat cgtagcttta
    29281 acaactcgaa attagtatag gccgctaatt tcaatcatac aacaaaattt tgttagcagc
    29341 ctaagtataa gtatatcgat atagatcagt gtgattcgct atgagcgact tcggcattgc
    29401 catgattctg gcagccaact tcttcacaac gttgcatcat gtaacccaga gcgaccagca
    29461 ctactgttga taacatcacg ctggtggtgg tgagcaatgg cgtgctgata ctgataagcc
    29521 aggaaactac cagacttgcg aggaagcaca gacccagttg cagagtgttc tgcaacgctg
    29581 cggcgcgacc ggttgcatgt gggaagggac gcagcgcctg ggcgacaaca atcgggtaga
    29641 tcgcaccgtt ggcaatcgcc atcacacaga atgggatcag gatttcgacc agcgacacat
    29701 ggctaatgaa gcccgcagcc caggtcgcaa tgacgctgac agcaaacagt accagcaacc
    29761 acggtaataa ctgcttgcct tgccatttct gcagcgcggc gcgacagcca taaccaccaa
    29821 tcagaaacgc gatagtttgc gggacataac ttaaaccaat aactgccggg ctgtagccca
    29881 tttcactaag gatgaacggt gagccggtca gccatgcaaa aaaactggct gaacaggccg
    29941 catatatcag cacgttgccg cgataggttt tagaacgtag caggtcggta aaggtcagac
    30001 catcctgact attgttacgg gccttcgtcg tgggtttgag ccagaaaata ggcagaatca
    30061 gcaccacggt aatggcaaac agggtggcga aaatcgcctg ccaggaaaaa tggaccagca
    30121 gccagcttcc taacagagga gccagtgccg gagatagacc caccagcggc atgatggtcg
    30181 caaaaatacg gttaactttc tgtgaaggat aataatccgt cactaacgct tgccagataa
    30241 ccgccgcggc gcagacaccc acagcctgta caaaacgcaa taccagcagc gtagcggcgt
    30301 tttctaccca cagcatcccc agactaccta acgcaaaaat tgtcaggccg attaataata
    30361 ccggtttacg accataacgg tcggagagcg gcccccacag aagctgggct gcggcaaatc
    30421 cggcaaggaa cagactaagg ctggcactga cagcagacgc aggcgtttgc aggtcggcct
    30481 gtatggcggc gaaagcaggc agatacatat cggttgccag aaaaccgagt acgctcaaac
    30541 ctgccagcca gactaaaaat cttttcccag gttgcatgta tattctctaa atctctcaat
    30601 taaacaccgc cgcaaagtgt agggagtgaa attagtgttg tgaaacggta atatttgatg
    30661 actggtttca aaaattttgc aggcagacta tgtggtcaga atattcactc gaagttgttg
    30721 atgcggtagc gcgtaatggt agttttagcg ctgcagccca ggagttgcat cgcgttcctt
    30781 ctgcggtcag ctataccgtg cgtcagctgg aagagtggct ggcggtgccg ctgtttgaac
    30841 gacgtcaccg tgatgtggaa ctgaccgctg ccggggcgtg gtttctcaaa gaagggcgct
    30901 ctgttgtcaa aaaaatgcag atcacccggc agcaatgtca gcagatagcg aacggctggc
    30961 gcggtcagtt agctatcgca gtggataata ttgtcaggcc agaacgtaca cggcagatga
    31021 tcgttgattt ttatcgccat tttgatgatg tcgaacttct tgtctttcag gaagtgttca
    31081 acggtgtctg ggatgcgctt tccgacgggc gcgtggaact ggcgattggc gcaacacgcg
    31141 cgattccggt aggtggtcgt tatgccttcc gggatatggg gatgctaagc tggagttgcg
    31201 ttgttgccag tcaccacccg ctggcgttga tggatggccc gttcagcgat gatacgttgc
    31261 gcaactggcc gtcgttggtg cgcgaagaca cctcgcgaac gctacctaaa cgtattacct
    31321 ggttgctgga taaccaaaaa agacttgtcg tgcctgactg ggaatcatcg gcaacctgta
    31381 tctctgcagg attatgcata gggatggtgc caacacattt cgccaaaccg tggcttaatg
    31441 agggtaagtg ggtagcacta gaactggaaa accccttccc ggattcggca tgttgtctga
    31501 catggcagca aaatgatatg tcgcctgcgt taacctggtt gcttgagtat ctcggcgata
    31561 gtgagacgct gaataaggag tggctgcggg agccggaaga gactcccgca acgggtgatt
    31621 aacgacgata gtcgcggaac gggccgtcag ccacggagcg gcgttcaatc aaccgcggat
    31681 gcacttcaat ggattgcggt tcttcgcgtt tattgacgat acgatccaac agcatgttga
    31741 acgccgtttc gcccagcgaa tcttttggct gatggatcgt ggtcagcgcc ggcgtaaaat
    31801 agcgggcgtt gcgcacgtta tcataaccga tcagcgaaac atcctgcggc acgcgcagac
    31861 ccatttcatc agcagcacaa agtgcgccca ttgccatgat atcgccacca cagaagacgg
    31921 cagtagggcg atgcggttgc gacagtattt gctgcatggc gcgataaccg gattcaggtt
    31981 caaaatcacc ctgtacaatc cagctttccg gcaccttgat catcgcttct tccatcgcct
    32041 tcataaaacc ggcaaggcgg cctgcgccag tgttacgttc cagcggaccg gggataacgc
    32101 cgatttcgcg gtgaccgcgt tctatcagat aacgcccggc catgtaaccg ccttcgaacg
    32161 cgttatcaat gaccgcatcg gtgaagtcag cttttgcttc accccagtcc attaccacca
    32221 ttgggatatg gcgatactct tccagcatcg ccagcaacgg ctctgggtac tcagaacaca
    32281 tcaccagcag accatcgacg cgtttttgcg ccatcatcga cagataagct cgctgtttct
    32341 caagattgtt ccacgcattg cccagaatca gggtgtaacc tttctggaag caattttttt
    32401 cgaccgcttc aatgatctcg gcaaaatagg ccgcttcgct gctggtcgcc agcaaaccga
    32461 tagacttagt gtggttaacc ttcagactac gcgccaccgc gctaggggag tagtgtaatt
    32521 ctttgatcgc tgcccacacg gcgttgcgcg tttcttcagc gacgaaacgt gttttgttga
    32581 tcacgtgtga cacagttgta gtggaaacgt ttgctcgttt cgctacatct tttattgttg
    32641 ccattccatt tcactccaga ccctaacttc agctcctgca aaatcgcaag gtaaacgttt
    32701 gcctttacac accttacgca caacaaaagt gttgcggtac gccggaaaaa cgacacggag
    32761 cgtcaggaag gggtcaatgg ccagtacgca aatagtgtaa gcgtggaatt ttggccgatc
    32821 ttgacgaaaa ggggaagtgg taaaaacact tatcattata aatgacggga gattttttca
    32881 tcatagtgtg taaaaatgcg taatatcact ttttgtgtgg taataaaaaa ggagaaaact
    32941 tgatgagcac cgaccttaaa ttttcactgg taacaacgat tatcgtcctc ggtttgatcg
    33001 tggccgtggg tttgactgcc gcgctgcact gatttcctct cgagggagcg cgttctccct
    33061 cgcatctcct tcctgtttgt tagcaaaatg gcaaaagtgt tttctctttt tgttattttc
    33121 atttttttgt gattgctgtc atgctttcgc cactttaatg aatatcgcgt aatgacgcga
    33181 agaggtggag ataaggcatg aaaattaact atccgttgct ggcgctggcg attggcgcgt
    33241 ttggtatcgg gacaacggag ttctcgccaa tgggcttgtt gcccgtcatt gcgcgcggtg
    33301 tggatgtctc gattcccgct gccggaatgt taatcagtgc ctatgcagtt ggcgtaatgg
    33361 tgggcgcgcc gctgatgacg cttctacttt ctcatcgtgc ccgccgcagt gcgttgattt
    33421 tcctgatggc gattttcacg ctcggcaacg tactttccgc catcgcgccg aattatatga
    33481 ccctgatgct ttctcgcatt ttgaccagcc tgaatcacgg agcatttttt ggtttgggtt
    33541 cagtcgtggc cgcaagcgtg gtgccaaaac ataaacaggc cagcgcagtt gccactatgt
    33601 ttatggggtt aaccctggca aatatcggtg gcgtgccggc ggcgacctgg ttgggtgaaa
    33661 ccatcggctg gcggatgtca tttctggcaa cggcggggct gggagtgatt tcaatggtaa
    33721 gtctgttctt ctcattacct aaaggtggtg caggggcacg acctgaagtg aaaaaagagc
    33781 tggcggtatt aatgcgtccg caggtgctgt ctgcattgct gacgacggta ctgggagctg
    33841 gtgcaatgtt taccctctac acctatatct ctccggtact gcaaagtatt acccacgcaa
    33901 caccggtgtt cgtcacagca atgctggtgc tgattggtgt cggattctct atcggtaact
    33961 atctcggcgg caaactggca gatcgttcag ttaacggcac gttgaaaggc tttttgttgc
    34021 tgctgatggt gattatgctg gcaatcccgt tcctggcccg caatgagttc ggcgcagcta
    34081 ttagcatggt ggtgtggggc gctgcaacct ttgcggtcgt accgccgtta cagatgcgcg
    34141 tgatgcgtgt cgccagtgaa gcgccaggtc tgtcttcatc agtcaatatt ggtgccttta
    34201 atcttggaaa tgcgctggga gcagctgctg gtggtgcggt aatttccgct gggctgggat
    34261 acagctttgt gccggtgatg ggggcgattg tcgcgggact ggcattattg ctggtgttta
    34321 tgtcagccag aaaacaacct gaaacagttt gcgttgccaa cagctaatta aacaaaaacg
    34381 cagaaggata accttctgcg ttacagtagc tggcaacgtg cgatttatct tgccggatgc
    34441 ggtgttaacg actcatccgt gttggcatgg taagcgaagc gcatcaggca atgctgcatt
    34501 tgccatcagt tattatgcag cgagattttt cgctacgaat tcccagttca ccagcgccca
    34561 gaagtgctcc agatagccag gacgtgcatt gcgatagtcg atgtaataag cgtgttccca
    34621 gacatcaacg gtcagcagcg gagttgcatc ggtggtcagt ggagtacccg cgttagaggt
    34681 tgaaacgata gccagcttgc catcgctgtt tttcaccagc caggtccagc cagaaccaaa
    34741 gtttttgatc gctgcatcag taaactgagc tttgaaatcg gcaaagctgc caaaagatgc
    34801 ggcgatagct tcagcgactt ttccagtcgg ttcgccaccc gcgttcggtg ccaggcagtt
    34861 ccagtagaaa gtatggttcc agacctgagc tgcgttgttg aatacgccac cttcagagct
    34921 gcgaataatc tcttccagtg atttaccttc aaacgcggta cctttaatca ggttgttcag
    34981 gttagtcaca taagtctgat gatgcttgcc gtagtgatac tcgatggttt ccgcagaaat
    35041 gtgcggtgcc agagcatctt tagcatatgg tagtgcaggt aattcgaatg acattgctac
    35101 tctcctttat tattaatttg catacgtaca atagccttat tgtgcgtatg gatagggtag
    35161 caaattaaaa ggtgagacaa aagatgaact taccctgttg ccgtaacaac agggtaaagt
    35221 tttagcgaag tgtttttggg gtcattaccc ggcgagcgcc aacatagtgg cgctgccagt
    35281 agtcttcact gagagaagtg atttgaattt cctgacccgt acgcggtgac tgaataaatt
    35341 tgccgttgcc gacatatacg ccgacatgat cggctgtacc gcgtccctga gtacggaaaa
    35401 agaccaggtc gccgtttttc agttcactac gttcgattgg cgctgcatct cgcaggtgat
    35461 acatttcatt cgccgtacgc ggaatacgaa ttttcaccaa atctttataa gcgtaataaa
    35521 ccaggccgct gcaatcaaaa ccggtacgcg gtgagctgcc gccccaacga tatggcttac
    35581 caatttgctg catcagttta ttcattgcca ctttcgtggc tttttgcacc ttcgctttgt
    35641 gcgcgtcggc aagggttcct gacgcggcat ttttgacttt cacacaatgc gatttatagc
    35701 ccttacgttt ggtacacttt tcggtaaagt tggctgaggc cgttttattg acggcgtgtt
    35761 tgctgcgagt tttggcgttt ttagaagcgg taatggaaga ttttttaacg gaagaagcgg
    35821 ttttgctttt gatcgtactt ttactggcgg cttttttcgc tgttttctgg ctggctttct
    35881 gggtcttttt ggtggttgcc gtgcttttct ttttatctgc ttttttggtg atatgagtag
    35941 tagcagaact ctccctggct tgctttgaag catgggccat aggcgttaaa ggcagggtgg
    36001 taaaaagtaa agcacagagc gtgatcgaaa tacggtttat ccgcgccact gagcgtccct
    36061 ctgttaaggc aggtctatca tgcctgcgtc tgatttacaa aacttgatga ttctaatgca
    36121 tagaagaaga gaaagttaat agcttttatt gttaaaaaat acgtttcgtc ggcgagcgca
    36181 aaaaaatgca gcagtgaaag ctaaaaatgg ttataaacac gccagtttgc cgtgcataag
    36241 ggaagaaacg aatatttgaa atgcaacaaa tagaacaaag ggataaaata gcaaaagcgt
    36301 gatgaaaatg ttattttccg atgccgcact gacccgctac aatgtcagat tactgccgta
    36361 aagaagtttg aggaagcaag acaatgagca ccactatcga aaaaatccaa cgccagattg
    36421 ctgaaaaccc gatcctgctg tacatgaaag gttcaccgaa actgccgagc tgcggtttct
    36481 ctgcccaggc agtccaggcg cttgccgcat gtggcgaacg ttttgcctat gttgatatcc
    36541 tgcagaatcc ggacattcgt gcggaactgc cgaaatatgc taactggccg actttcccgc
    36601 aactgtgggt tgacggcgag ctggtcggcg gttgtgatat cgtgatcgaa atgtatcagc
    36661 gtggcgaact gcagcagctg atcaaagaaa ctgccgctaa atacaagtct gaagagccgg
    36721 acgcggaata atccgtcctg caatactgac ggatgcgaac gggcatccgt cagttcttta
    36781 tctatcccca atccagccct tgtggcgaac ttgaaaatcc cgcctcacgc agcagcgtaa
    36841 acatcggcgt ttgtcggact ggtagatcat tcacttctgt cagcgtaaag cgcagccgtg
    36901 gttcgcgacg cagtgcggta gtcagcgcgt ggaaaacctc tggggcgagt aattcctctt
    36961 tttcctgcca gaccagcatt tttttgccac cttgcgccag ataaagtaac aatttgccgc
    37021 cagaaacgac caccagcgca cccgcccgac gcgttggaac cagcgttgcc ggatgtgcag
    37081 gccagggcag aagatttccc cacacattag ccggatcgtt ggcggagagc gccactggtg
    37141 tatagtggcg cgtttgcgcg gtttgtgtcg ccaggtcacg caatcggtca atagtcagac
    37201 gttcagcgaa ttgcgcgcca cccagacctt ctacaaaacg accccgcata attcgcccgg
    37261 agtcttccat acttcgacaa agcgtttgca tcgatggaaa accgccaggg atattttcgg
    37321 ctatcaccgc ctgacgactg atgatgccgt agcggtcgag catattttcc gccagcgcca
    37381 gcatcctttc ggtatcgttt agtggctcca cctgcaataa cgaccagcgt ccggccagct
    37441 ttggtgtgtt gtaagatacc cgcggcgaga cgggttgcgc atagacagga cgcccacgac
    37501 gagcccggtg actgcggcga gttgaggtgc gtgcgttgga actgctgcgg gtgagggcgc
    37561 gtaacggtgc ccaaatatcg ctggtgatga cgccttgcca gaccagcgcc cataacgcct
    37621 cttgcagtgc cgagggatca accgattcgc cgattttatc gcgtatccgt tggctgattt
    37681 gttgtgcaaa ccaggctcct ccgtcagcca gaacagcgac tatcgcttgc tgcagcgccg
    37741 aacgattcgc ctgatccgct tcggcgggag tgaacgattc tgcggcatat tcctgtagat
    37801 gcagtgccac caggccgtca tcttcaccca gctttttttg tcccgaccag ataaccgctc
    37861 cggttgccag taattcatcg agcatttctg gcgaatagtc gcgtacgcgg gcaggcagga
    37921 tctggctttc ccagagtgag gcgggtaaac cgactcctgc aagctgttcg atcacccgca
    37981 tcacgccatc cacgccctca taaacgcctg gcgatgttga ggcaaagagt gccgggctac
    38041 catcggtggc gggtaatacg ccctgacgtt ccagcagcaa tcgcgcatag gtcgtggccg
    38101 caacgggacg tgtcgcttct ctggcggctt gcagcgagcg caaacgcaga cgacgaaata
    38161 cttcatcgct cacccagatg tcttgttgca gattcatcac cagaccctgt tcgcgcagtt
    38221 gctgaagttg ctcttcgaca atggcaatac cgagactaaa ctcatgagcc agttgttcag
    38281 ccgtgaccag agcatgagcc cggagatagc gcagaaagag gtcgcgaagc gggtaactga
    38341 ctcggtgcaa ataaatctct ggcagtgact ctggtagtcg tacgccgagg gcatcgcgca
    38401 gcctggcggc atcatccata caggcaagac gctcctgccc gctaatcatc gtcgggaaga
    38461 ttcgttttac tgcaagaaga ttttccagat acgacgcaat ctcttcactg ctgcctgtat
    38521 gccgttgcgc caggtcttca acggtcattg gccccagttc gcgcagcagg tcgaacaatc
    38581 cttcttcacc tttcgctctt ctgccaggag ccagtcgttg caactcttct tccacctggc
    38641 gaatgacctg cgggtcgagt aattcccccg gttcgacctg tccgagtaga ttgcgcagta
    38701 actcgctgtc cagcgacagt acggatgccc ggcgctctgc cagcggggcg tcgctctggt
    38761 acataaattc cgcgacatag ccgaacaata aactggcggc gaaaggcgag ggcgtagtgg
    38821 tcgttacatc ggatatttga atttcgccac cgttcaggcg acgcatcaaa cgttccagcg
    38881 cgggaagatc ataaacatct tgcagacatt cgcgtagggt ttcgagaatg accggaaaat
    38941 ccggatatcc ctgagcgatt tccagcaact gactggcgcg cagtcgttgt tgccagagcg
    39001 gggtgcgatg gcccggcgtg cggcccggca ttaataatgc ccgcgcggcg cattcgcgaa
    39061 aacgggcggc gaaaagtgcc gagctgccta ccgcctcgcg gacaatttgc agcaactttt
    39121 ctggttcaaa caaaaaaatc gcggcatcag gcaatttacc atcggtgtca ggaatgcgcg
    39181 caacaatgcc gtcatcactg gcaaccacag acgcgtcagc gccccatagt gcatgtattc
    39241 gcccggcaat cgccagcgcc cagggttcat gcacccgtct tccataggga gagtgcaaaa
    39301 taatacgcca gtcaccaatt tcatcacggc accgttcgag gacaagatga cgactacccg
    39361 gaacgatacc cgtcgcgttg cgctgctcgt caatcaaccc ctgaatattg gcgatcgtat
    39421 tttcttctgc caaccacggg ggaatagtcc cggaaaagaa cgcgccatcc gccagtaaat
    39481 ggagaaaatc gccgatcatc tcgcctaatt ctgccggacg tccgttacct tcaccacgcc
    39541 agaagggaag gcgggcagaa cgacccggag caggagtcac aatcacctga tcgcgggtga
    39601 tttgctggat ccgccatgag gttgcgccaa gagtgataat atcgttcacc cgtgactcat
    39661 ataccatctc ctcatccagt tcacccaccc gccgcgaacc ggcctgttct tcaccttcgg
    39721 gtaataacac gctatacatg ccacgatccg gaatggtgcc gccgctggta accgccaaca
    39781 attgagcgcc aggtcgggcg gtcaatatcc cggtctccct gttccagacc agtttggggc
    39841 gaaaagcaga aaaatcgcca gagggatagc gcccggaaag catatccagc gtggcgtcaa
    39901 aaacacgtcc tggcagatct ttccacggtg cggcacggcg tacgcgggag taccattcgt
    39961 ctacctgtaa tgcatccatc gccgcggcgg caacggtttg ctgcgcaagg acgtcgagtg
    40021 gattatgcgg tggtgtcagg ttttccagcc tgcctgcgaa catacactct acaatgactg
    40081 cggaatcgac taagtcacgc cgggttcggg ggaaaaaaag ccctttagat acaccgccaa
    40141 cctgatgtcc ggcacgtcca atgcgttgta acccactggc aacagaaagc ggcgttgcca
    40201 cctgaatcac cagatccacc gcgcccatat caatccccag ttcgagactg gaggttgcga
    40261 ccacgcagcg taattcaccc gatttcagcg cctgttcggt gattgctcgt tgttctttag
    40321 agacggagcc gtggtgtgag cgggcaataa aaatgtcgct actttgtaca cggttagagg
    40381 ttgcgccgga ggtcgactcg aaatgggccg catcaacggc gatagacggg gaacgctgta
    40441 agcgagcggc gtaaagctca tttaatcgtg ccgtcagttt ttccgccagc ccgcgcgaat
    40501 tagtaaagat aatggtcgag cgatggcgca acacttcatc aaggataccc gtttcaatat
    40561 atggccagat ggagccttcc cggccggcat ggctgtcttc gccggtgccg ctggcgactg
    40621 atgagacatc atccatattg gcgaccggta cgacaatccg tatctgcgga tggcgcattg
    40681 cgggcgggtt gactaccgta accgggcgat cgccaccaag aaatgctgcc acatcgctcg
    40741 ctgagcgcac agtggcagaa aggccaattc gctgtgctga ggtgtggagc agcgcatcga
    40801 gccgctccag acttaacgcc agatgcgcac cacgtttact gcctgctacc gcgtggactt
    40861 catcaataat taccgtttcg acgccgcgta gcgtttcgcg cgcgcgggag gtcagcatca
    40921 gatagagtga ttcgggtgtg gtgatcagaa tatccggcgg attacgggtg agtttgctgc
    40981 gttcctgtgc aggcgtatcg ccagtacgga tcgccacgcg aagattgact tccgtttcgc
    41041 cgcgccgccg ccgttcatcg gcaataccct gtaacgggat ctgcaagttg cgctgaacgt
    41101 cggtgcccag agctttgatc ggtgaaatat agagaatgcg tgaggtttta cgcttatgcg
    41161 cctcgcgggt atcttcgccg ccttcgcgga agagctgatc gagggcgtag agaaatgctg
    41221 ccagcgtttt cccggagcca gtcggtgcaa tcaccagcgc atgttcgcct cgcgccgcca
    41281 catgccaggt ttgcgactgg acagcggtcg gctgtttaaa ggcgcgaaga aaccagtcgc
    41341 gggtcgccgg tgaaaacacg tccggcaggg gcgaggaagg gtttagatta tctgccatta
    41401 acgctattcc ccgtgaatat catgcatgat gcgtggaata gcctcactat agatgcctga
    41461 atcattgcat gtcatcaggc atcgactcga ttacacctct tcggcggcag gtagcggcca
    41521 gcctcccaga cgtttccagc ggttgacgat ttcacaaaac agcacagcag tgcgttcggt
    41581 gtcgtacaac gcggagtgcg cctgggtgct gtcgaagtcc atgccagcgg tctggcaagc
    41641 ctttgacaat acggtttgtc cgagtgccag cccggccagt gcagcagtgt caaaagtggc
    41701 gaaagggtgg aacgggttac gtttcagtga ggcgcgttct gcggcggcca tcataaagct
    41761 gtgatcgaaa ttggcgttgt gcgccaccat aatggcgcgg ttacagccgc tcgctttaat
    41821 gcctttacgt acaactttaa aaatttcgtg cagcgcctcg tattcgctga ccgcgccgcg
    41881 atcgggatcg ttcgggtcaa taccgttgaa ggcgagggcc tctggctgca aatttgcgcc
    41941 gacaaatggt tcgacgtgga aatgtaatgt ggtgtccggc atcagccagc cttgttcatc
    42001 cattttcagg gtgatggcgg caatctcaag cagcgcatcg gttttggcgt taaatccggc
    42061 tgtttcaaca tcgatcacaa caggataaaa accacgaaaa cggtcgcaca gaccggtaag
    42121 ttgagcgtta tcggacatct gattctctta atacggataa attgcagcgc gcattatgac
    42181 aaatattact tgtcgatgca gtaaagatgc gggcgcgagg agttcacgcc cggcaggaga
    42241 ttagttgccc agaccgcgac cggcgtcttt ctcttcgatt aactcaattt tgtaaccgtc
    42301 cggatcttcc acaaacgcga taaccgtagt accgcctttt accggacccg cttcacgggt
    42361 cacgttaccc ccgttttgac ggattttttc gcacgcttca gcggcgttat caacgctaag
    42421 cgcgatgtga ccataagcag tgccgagttc gtatttatcc acgccccagt tgtaggtcag
    42481 ttcaatcacc gcttcttcgg tttccgggcc gtagccaaca aacgccagtg agtatttgta
    42541 ttccgggttt tcgctggtac gcagcagttt catgcccagt actttggtat aaaaatcgat
    42601 ggagcgttgc agatcgccaa cgcgcagcat ggtatgaaga agacgcatct ttatatcctc
    42661 aaaatggcta acagattcaa aatgttgttt tagtatagcg gcggctttgc gccgctcgca
    42721 atgttggatt acagcgtcgg gtaatcagtg tagccttccg cgccgccacc gtaaaaactt
    42781 tcggcacgct gtgggttaag ctcagctttg cgttgcaagc gggcgaccag atccgggttc
    42841 gcaatccagt cacgaccaaa tgccaccgca tcaattaacc ctttgccgat cagcgtttcg
    42901 gctttttcta ccgtgtatgc acctgcgccg ataatcggac cgtggaaacg ggcgcgtact
    42961 ttttcgcgga acgcatcagt atacggctca ccccccgccc aatctggttc tgacatatgc
    43021 agataagcaa tgccgcgttt acccagttgt tcaatcagat acagtgcatc ggcttcttca
    43081 ttcgggccgt tatctgtgtt ctggaaagta ccgattggcg aaacgcgaat gccaatgcga
    43141 tcggcacccc attcttcaat ccctgcatcg accacttcca gcaccagacg tgcgcgattt
    43201 tccacgctgc cgccgtactg atcggtacga tggtttgaag aaggagaaag gaactgatgc
    43261 agcaaataac catgagcaga gtggagctct accagatcaa aaccggcttc acgcgcgtta
    43321 gaaatggcct gacggaaatc attgacgata cccggaatct cttccagttc aagcgcacgc
    43381 ggcatggatg tttcaacacg gatcgcctga ccattttcat cgcgcagaga agtacgtgtt
    43441 cccgcgctaa gtgcggaagg cgctaccggt gcctgaccgc caggttgcag gctggcgtga
    43501 gaaatgcgtc cggtgtgcca cagctgtacg gccatatgac cattttcagc atgaacgcca
    43561 gcggtaattt ttttccatgc ggcaatttgt tccggactat ggatgccagg tgcaccagca
    43621 tacccttttg cctgggcaga aatttgcgtg gcttcgctaa taatcaaacc ggcactggca
    43681 cgttggcgat agtattccgc catcaacggg gtagggatgt cacccggttc aatactgcga
    43741 agacgcgtca gcggtgccat aaaaatacgg tttgccgccg tgatcgcgcc cactttcagt
    43801 ggggaataca gtttttcaga tgacataaag gctcccggtc gtctggtgat aaaaaatgcc
    43861 tgctaaacgg caggcgtcgc aataatggtt tttacatgtg ccagcgcgtt ttccagtggc
    43921 tcggaattgc gcgaaatttt ggcctgcaga ttcgcaccca gccacagtgc gtaaagcact
    43981 tgtgcctgtt gcagcggttc gccacaaaag gttaaacaat ggctatcacg gccattttcc
    44041 agcgcctgcg agagcagggc gatcacgccg cgagcgcctt tatccatcgc gctacgcata
    44101 tcttctgaca gatcgcacac ttcggcagag agttttactg tcaggcaacc actgatggtt
    44161 ccatgttggc aaaactggtt cagtgtttgc tggtaataag ccagtatgcg gtcgcggtag
    44221 ttaccttcgc cggattgcag caactcagtc agtcgctggt gatatgcggc gtaatggcgc
    44281 tcaagcatgg caacgccaaa cgcttcttta gagcgaaagt agtgatagaa ggaccctttc
    44341 ggcacttcag cagtttttag gagttcgctt agccccatcc cggtgaatcc acgttgcagg
    44401 caaagttgct cgcccgtcgc caggagatgt tcgcgagtat catgttcggt gtgtttgttc
    44461 atgcgttgga gtgtagtaga ccagtcggtc tagtgcaagc aaagttgcta ctttgggcat
    44521 taacagcttc aatagtggta ataatcttat ctgaggaggg cgaagtggcg gagcaattag
    44581 agttctttcc cgtccagagc ccgtgccggg gaatttgcca gtctgacgaa cgcggatttt
    44641 gtcgcggctg ctttcgcagt cgggatgagc gttttaactg gaataaaatg agcgatggcg
    44701 aaaaacaaga ggtactgcgc ctttgtcggc agcgattaat gcgcaaatta cgtgcaaata
    44761 agccggcgtc atcagatgaa ccggagcaac catcactctt ttgagcctaa tcttgcgtat
    44821 actcctctca tatctgataa gaggaagcga ttatggttca gcgtattact attgcgccgc
    44881 aaggcccgga gttttcccgt tttgtgatgg gctactggcg attgatggac tggaatatgt
    44941 ccgcccgcca gctggtcagt tttattgaag agcatctgga tctcggcgtg accaccgtgg
    45001 accatgctga tatttatggt ggctatcagt gcgaagcggc gtttggcgag gcgctgaaac
    45061 tggcacctca cctgcgtgaa cggatggaaa tcgtcagtaa atgcggtatc gcgacgaccg
    45121 cgcgtgaaga aaacgtcatt ggtcattaca tcactgaccg cgatcacatc attaagagcg
    45181 ccgaacagtc gctaattaat ctcgcgaccg atcatctgga tctgctgtta atccaccgac
    45241 cagacccgtt aatggatgcc gatgaagtgg cggacgcgtt taaacatctg catcagagcg
    45301 gcaaagtgcg ccattttggc gtatccaact tcacgcccgc gcaatttgcc ctgttgcaat
    45361 cacgcctgcc gtttaccctt gccactaatc aggtggaaat atccccggtg catcagccgt
    45421 tactgctgga tggcacgctc gaccaactgc aacaactgcg tgttcgtccg atggcgtggt
    45481 cctgccttgg tggtggtcgt ctgtttaatg atgattattt ccagccgctg cgtgatgaac
    45541 tggctgtggt ggcggaggag ttaaacgcgg gctcgattga acaggtggtt tacgcctggg
    45601 tattacgttt accgtcgcag ccgctgccaa ttatcggctc aggtaaaatt gagcgcgtac
    45661 gggcagctgt cgaagctgaa acactgaaaa tgacccgtca acaatggttc cgtatccgta
    45721 aagcggcatt gggttacgac gtaccgtaag cacttttagg aatagccgcc gttcaaaaat
    45781 gtgtcactgg tttacactta ttcaggaatg cacaatgaac ggaggtccta tgaaacgttt
    45841 tagtctggcc attctggcgc tggttgttgc gaccggcgca caagctgcca gtgaaaaagt
    45901 cgagatgaac ctcgtcacgt cgcaaggggt tgggcagtca attggtagcg tcaccattac
    45961 tgaaaccgat aaaggtctgg agttttcgcc cgacctgaaa gcattacccc ccggtgaaca
    46021 tggcttccat attcatgcca aaggaagctg ccagccagcc accaaagatg gcaaagccag
    46081 cgccgcggaa tccgcaggcg ggcatcttga tccacaaaat accggtaaac atgaagggcc
    46141 agaaggtgcc gggcatttag gcgatctgcc tgcactggtc gtcaataatg acggcaaagc
    46201 taccgatgcc gtcatcgcgc ctcgtctgaa atcactggat gaagtcaaag acaaagcact
    46261 gatggtccac gttggcggcg ataatatgtc cgatcaacct aaaccgctgg gcggtggcgg
    46321 tgaacgctat gcctgtggtg taattaagta attaagaggc cagcgtacct tgcggcggtg
    46381 cttgctcaag ttgcgaaagc gagcagtaca gccgccagac aattgccgcc agctcacggg
    46441 cggcaggttg atgatgacgg gcaaggctgt cgcaaattcg ctgtaattct tcaagtgtgg
    46501 ccgccagtga tttttgctga acgccacgct cactcatcac tccgcgcaac agtgaaatac
    46561 agttatcccg tactcgcgat aacggatcgg aacgcgattc ccagtcgcgc aattgccaga
    46621 caacatgaga acagttcagc agcactacac cccagcgtaa taaccaacgg cgagccatcg
    46681 catcctggct gttactcaac tgactgacgt gatgataagt gagcgattca aattcgcttt
    46741 cactcagtga tggatggcgg cttagttgat cgacaaaatc ccggcgcagc gcgcgaatat
    46801 gacgacggct tttacgagcg tcagacccag gtcgcagaat ggcgaacgct agccacgcca
    46861 acgcgacgcc aacaattttt gccagattat cgttaagaaa atcagcaaaa tcatacaccg
    46921 gaggattagt gacagcgata aacgaaccca taaaaacaat cagttgcccc cacagtgcgg
    46981 caaatttggg catctgcaat ttaagaagct gcatcgtcgc cagtagtggg aagagaaaca
    47041 gtaaaaattg ccacagatcg ctaatctgca ccatcaggcc aaatttgacc acaaagctga
    47101 atagcgaaag taacaccagc gtgcgcatta gcagtgacaa ggacttaaac ggtgccgcga
    47161 cggcggagta gagtacgcag ctaattgcgg ccagcgttaa tgcattggca ccggcatccc
    47221 attgcgaagc aatactccat gcgccaatca tcatcaacgt acaaaatgta cgcagtccgc
    47281 tccacatagc ttcggcgtta tcggtatgac gagccaggcc ggatgtccgt gggagtctgg
    47341 tatgatcatc cacaccgctt tgcagatgat gtaattcctg actactttgc agataaaggc
    47401 ggcaaaaata acgtagtcgc tgccagaagg cgacgtgccg atagtcggcg acgttggtcg
    47461 ggcgtagcgg ggcgataata cgtgcgacgg tgtaaacatc tgtttgcgaa ctggcgagcg
    47521 ccgtcagcag ctgttcgaga atttctcgtg tggcacctgg cggtgagggc cagttgagca
    47581 acatacgtcg caggctggag atgacactgg tcatacgtaa ttgctggtgg agcagcgcat
    47641 taaggcgtgc gttttgctgg cgaaaacgat agtggctcca gaaagcctgg atacggagca
    47701 aattcatggt cagtatctgc ccaatcaccc cttcatgtgc tgcacgaatg gcatcggttg
    47761 tttcaggctg ccagagtaaa ctggcatgtt ccagcaatcg ggcgtgcatg tttttcaatg
    47821 cggttaaaag ggctgtagca tcggaactgc tcggcaggat catcatcatc atgccgccgc
    47881 acaaaatacc gacaatcacc tcgcaaacgc gcgcctgagc gatatcccac agctggctgg
    47941 cctcagtaat attaaccatc ggaaaggcga tgatggcagc cgtgtagccc gccagttgaa
    48001 atgcatacgc gacattattc gtgaagtgcg cacaggccca ggtacaaaag ccaagccacg
    48061 ccgccatgct caaaagaaaa aaacacggct cattaagtgt atgtccggca agaagcagtg
    48121 ccgcaatggc tccgagcaaa ctgccagcga tgcgtccgag gcttttgctg atgacaccgc
    48181 caacggtggg aaagctaacc acggcagccg aggtcatcgc ccaatagggt tcatccagat
    48241 ttaaataata ggcaaccgtc agcgccagac acatggcaat agtattgcgt aacgcataac
    48301 gccattgcgc cagcgtggcc ctgaaccagg gcaaattgcg caaggaccat gacgatgcgt
    48361 tcattattga cctacggcaa tgctacaggt ggtgcccgac accagcgtga catcgcctgg
    48421 gactttatcc agcgcaaagc ggacgggaac gcgttgggcg agtcgaaccc aggggacgtt
    48481 aggtttcaca tccggaataa ggcttgagtc actttcaacg ctctgatcat aaatcgcccg
    48541 accgatactg gaaacgtgac cctgtaacgt tttgttatca ctatagaggg taatttgtgc
    48601 tggtgcacct tcgcggatat ggcgcaactt ggtttcttca aaataaccaa tgacgtaaaa
    48661 cgagtggctg tcgacaaggg caaacagcgg tttcccggtg tctgcgtaat cgccgatgcg
    48721 ggtagtgagg ttagtcaccc atccactcac cggggcgcga atttccgttt gcgccagttg
    48781 ccattgtgcc tgtttcagcg tcgcctgtgc ggcatcaaca ctggcctgca tcgctttaac
    48841 attgaggtta gcggtatcga gttcttcggc agaaataaaa ttttgtgaga gatgacgacg
    48901 acgattcgct tcattattgg cttttgcgag gtcagattgc gctttcgcca gctgagcctg
    48961 tgcgttcagc tcggcgatct gaaagggcgt tttatcgatc gtgagcagaa gatcccccgc
    49021 gttaaccagt tggttgtctt ttatattcag ctcaacaata cgtcccgaca cctgaggggt
    49081 gatagaaacc tgttctgcgc gtattttccc gtcgcgtgtc cacggagatt gcatgtaata
    49141 attccacagc caccatccgg caagaaccgc aactaccgct acaatgattg ttgagaaata
    49201 cttaattgtt ttaattgaca tagttaccac gcaatcagta ttgccagggc aaggcaaacg
    49261 caaatcgcaa acagcgataa atccattaac aagggatgcc agatgtcacc ggcgtagatc
    49321 cagccacgaa gcaggcggtg tacgacaagc cagatgacga atccaaacgc gaaggctttg
    49381 aaaaacggag gaaagtagac ggacgcaccg aacaccagat cttgtaaggg caatcctgtt
    49441 gcattgagca taaacttcac aaagtagatt cctttacgac cgaatatatt gcgttagatt
    49501 aataaatatt ctttaagtgc gaaaaattta cgcgcaattt ctgaaaaata tgtctgacgg
    49561 taaccaaatg cagcaataca tttgttttag caatacaatt gctgcacact attctaaaag
    49621 ccgcataata tcttagcaag ctaattataa ggagatgaaa ttggaatcgc cactaggttc
    49681 tgatctggca cggttggtgc gcatatggcg tgctctgata gaccatcgcc tgaaaccgct
    49741 ggagttaaca caaacccatt gggttacgtt acacaatatc catcagttac ctccagacca
    49801 gtcgcaaatt caactggcaa aagcgattgg catcgagcag ccatcactgg tccgtactct
    49861 ggaccaactg gaagaaaaag ggttaatttc gcgtcaaact tgtgccagcg atcgtcgggc
    49921 taaacgtatt aaactgacgg aaaaggcaga gccgctgatc agcgaaatgg aagctgttat
    49981 taacaaaacc cgcgcggaaa ttttacatgg catctccgca gaggaactgg aacaactgat
    50041 taagctcatc gcaaaacttg agcataatat cattgagtta caggccaaag ggtgaaatga
    50101 agggggcgtg tggtcagtaa cctgaccaca cgcaaactta tttagcgcgg ggaaacggtc
    50161 acctgactgc cattgctggc cagtacgaca cgttggcccg gagagaaacg agtgttgcct
    50221 tgtttctgta ccaccatgat ggtattacca tcgtctttac gaatttccag ctcgacaccc
    50281 tgcgttttgt tcattgcact ctgtacgccc tgaccggcta cgccacctgc aacagcgcct
    50341 gctgcagtag ccagagaacg cccggttccg ccaccaacag tattccccag gaaaccacca
    50401 agaacagcac cgccaattgc accgataacg ttagaatcat caccgccctg aatctgtacc
    50461 ggacgtacgt taacgatggt gccatagctg acattctgta cttgtttcgc ttcagaagcg
    50521 gtataaacat cccctgacag ggtgtcgtta ttaacacaac cgacaagaga cagacctacc
    50581 attgaaacaa ccaatacgcg tttaatcatt gaaaaatctc ctgttcacca tgaaacgcca
    50641 cgcaagcatc cctcatggtc aaagtatatg gcatatgtga atccatggtt acatgttcta
    50701 ccaaatatga gcaaatcata atgaaagtag gatcaaccaa ttataaacaa aacattcatg
    50761 atgattattg atttgaagat aatgttttac taccaacgat aaaaatcggt cattccgcat
    50821 ggtattcacg aaaagtttat gtttgagtgg tgcgcaaacg tcagattgaa aaaggatgaa
    50881 ctatgaaatc gggccgcttt attggcgtta tgtcaggcac cagccttgat ggtgttgatg
    50941 ttgtgttggc gacaattgat gaacaccggg tcgcacagct ggcaagtttg agctggccga
    51001 tcccggtgtc tctgaaacag gctgtactgg atatttgcca gggccagcag cttacacttt
    51061 cgcagtttgg acagcttgat actcaactcg ggcgactttt tgctgatgcg gtcaatgcct
    51121 tgcttaagga acaaaacctg caggcgagag atatcgttgc gatcggctgt cacggtcaaa
    51181 ccgtctggca tgaaccgacg ggcgtggcac cacacacttt acagattggc gataacaatc
    51241 aaattgtggc gcgcaccgga attacggttg tcggtgattt tcgccgtcgc gatattgcct
    51301 tgggaggaca aggcgcaccg ctggtacctg cgttccatca tgcgctgctg gctcacccaa
    51361 ccgagcgacg aatggtgctc aatattggtg gcatcgccaa tctgtcactg ctcattcctg
    51421 ggcagccggt agggggctac gataccggcc ctggtaacat gctgatggat gcctggatct
    51481 ggcgtcaggc cggtaaacct tacgataaag atgccgagtg ggcacgggcg ggtaaagtca
    51541 ttctcccact gctgcaaaat atgctcagcg acccatattt ctcgcaacct gcaccgaaaa
    51601 gtaccggacg cgaatacttt aactacggct ggctggagcg ccatttgcgc cattttccgg
    51661 gggttgatcc ccgagatgta caggcgacac tggcagaact caccgccgtg accatttctg
    51721 aacaagtttt gttgagcggt ggctgcgaac gattgatggt atgtggtgga ggaagtcgta
    51781 atccgctact catggcgcgt ctggcggcat tactgccagg cacagaagtc accaccaccg
    51841 atgccgttgg cattagtggc gatgacatgg aagcattggc tttcgcctgg cttgcctggc
    51901 ggacgctggc gggattacca ggaaatctgc cttccgtcac tggcgcaagc caggagacgg
    51961 tactgggggc tattttcccc gctaacctgt gatatcagag ttaactgaat ttttcttacc
    52021 gcgtctgccg ttacacttgg aacgttaggg agggcgtatt gccctccaga ccaggaaagt
    52081 cttcgggata tgtctatgaa aaaactgtta ctgatctgtt tgccggtcct tctcaccggc
    52141 tgtagcgcgt tcaatcaact ggttgagcgc atgcaaaccg atacgctgga ataccagtgt
    52201 gatgaaaaac cgttgacggt caaactgaat aatccgcgcc aggaagtcag ttttgtttat
    52261 gataatcaac tattgcatct caaacagggc atttctgcgt ctggtgcacg ttacaccgac
    52321 gggatctatg ttttctggtc gaaaggcgag gaagcgactg tctataaacg cgaccgcatc
    52381 gtcttgaata actgtcagtt acaaaatcca cagcgttgag atttttccag gggcggcgca
    52441 caatagcgtc acccactgac aatccgtaaa gaaaaccatg tctgataacg acgaattgca
    52501 gcaaatcgcg catctgcgcc gtgaatacac caaaggcggg ttacgccgcc gcgatcttcc
    52561 cgccgatcca ttaacccttt ttgaacgctg gctctctcag gcttgtgacg ccaaactggc
    52621 ggaccctacc gcgatggtgg tcgctaccgt ggatgaacat ggtcagcctt atcagcgcat
    52681 cgttttactc aaacattacg acgaaaaagg catggtgttt tacaccaacc tcggcagccg
    52741 taaagcacat caaatcgaaa ataatccgcg cgttagcctg ctgttcccgt ggcataccct
    52801 tgagcgccag gtgatggtga tcggtaaagc ggaacgactt tcgactctcg aagtgatgaa
    52861 atattttcat agtcgcccgc gtgatagcca gattggtgca tgggtttcga agcagtccag
    52921 tcgcatttct gcccgcggta tccttgaaag taaattcctg gagctgaagc agaagtttca
    52981 acagggcgaa gtgccattgc cgagtttttg gggcggtttt cgcgtcagcc ttgaacagat
    53041 tgagttctgg cagggcggtg agcatcgcct gcatgaccgc tttttgtacc agcgtgaaaa
    53101 tgatgcgtgg aagattgatc gtcttgcccc ctgaaaagat gcaaaaatct tgctttaatc
    53161 gctggtactc ctgattctgg cactttattc tatgtctctt tcgcatctgg cgaaaagtcg
    53221 tgtaccggca aaggtgcagt cgttatatac atggagattt tgatggcaag cagtaacttg
    53281 attaaacaat tgcaagagcg ggggctggta gcccaagtga cggacgagga agcgttagca
    53341 gagcgactgg cgcaaggccc gatcgcgctc tattgcggct tcgatcctac cgctgacagc
    53401 ttgcatttgg ggcatcttgt tccattgtta tgcctgaaac gcttccagca ggcgggccac
    53461 aagccggttg cgctggtagg cggcgcgacg ggtctgattg gcgacccgag cttcaaagct
    53521 gctgagcgta agctgaacac cgaagaaact gttcaggaat gggtggacaa aatccgcaag
    53581 caggttgccc cgttcctcga tttcgactgt ggagaaaact ctgctatcgc ggcgaacaac
    53641 tatgactggt tcggcaatat gaatgtgctg accttcctgc gcgatattgg caaacacttc
    53701 tccgttaacc agatgatcaa caaagaagcg gttaagcagc gtctcaaccg tgaagatcag
    53761 gggatttcgt tcactgagtt ttcctacaac ctgttgcagg gttatgactt cgcctgtctg
    53821 aacaaacagt acggtgtggt gctgcaaatt ggtggttctg accagtgggg taacatcact
    53881 tctggtatcg acctgacccg tcgtctgcat cagaatcagg tgtttggcct gaccgttccg
    53941 ctgatcacca aagcagacgg caccaaattt ggtaaaactg aaggcggcgc agtctggttg
    54001 gatccgaaga aaaccagccc gtacaaattc taccagttct ggattaacac tgcggatgcc
    54061 gacgtttacc gcttcctgaa gttcttcaca tttatgagca ttgaagagat caacgccctg
    54121 gaagaagaag ataaaaacag cggtaaagca ccgcgcgccc agtatgtact ggcggagcag
    54181 gtgactcgtc tggttcacgg tgaagaaggt ttacaggcgg caaaacgtat taccgaatgc
    54241 ctgttcagcg gttctttgag tgcgctgagt gaagcggact tcgaacagct ggcgcaggac
    54301 ggcgtaccga tggttgagat ggaaaagggc gcagacctga tgcaggcgct ggtcgattct
    54361 gaactgcaac cttcccgtgg tcaggcacgt aaaactatcg cctctaatgc catcaccatt
    54421 aacggtgaaa aacagtccga tcctgaatac ttctttaaag aagaagatcg tctgtttggt
    54481 cgttttacct tactgcgtcg cggcaaaaag aattactgtc tgatttgctg gaaataatgc
    54541 attaagtgga aagggggagt gagaaatcac tcccctggtt tttatacagg gaacatgatg
    54601 aaaaatattc tcgctatcca gtctcacgtt gtttatggtc atgcgggtaa cagtgcggca
    54661 gagtttccga tgcgccgcct gggcgcgaac gtctggccgc tgaacaccgt tcaattttct
    54721 aatcacaccc aatacggcaa atggaccggc tgcgtgatgc cgcccagcca tttaaccgaa
    54781 atagtgcaag gcattgccgc cattgataaa ttacacacct gtgatgccgt attaagtggc
    54841 tatctgggtt cggcggagca gggtgaacat atcctcggta tcgtccgtca ggtgaaagcc
    54901 gcgaatccgc aggcgaaata tttttgcgat ccggtaatgg gtcatccgga aaaaggctgt
    54961 atcgttgcac cgggtgtcgc agagtttcat gtgcgtcacg gtttgcctgc cagcgatatc
    55021 attgcgccga atctggttga gctggagata ctctgtgagc atccggtaaa taacgtcgaa
    55081 gaagcggttc tggcagcgcg tgaactcatt gcgcaagggc cacaaattgt gttggttaaa
    55141 cacctggcgc gggctggcta cagccgtgac cgttttgaaa tgctgctggt taccgccgat
    55201 gaagcctggc atatcagccg tccgctggtg gattttggta tgcgccagcc ggtaggtgtt
    55261 ggtgatgtga cgagcggttt actgctggtg aaactgcttc agggggcaac gctgcaggag
    55321 gccctggaac atgtgaccgc tgcagtatac gaaatcatgg tgaccaccaa agcaatgcag
    55381 gaatatgagt tgcaagtggt tgctgctcag gatcgtattg ccaaaccaga acattatttc
    55441 agcgcaacaa agctctgaaa tatctcattt cggcccacaa cgacctgtgg gccgatggct
    55501 attactttaa gccttccgct gacagcgcgt cttgtacttc cggacgttca gccatacgtt
    55561 gcataaatgc cgcaatgtgc tctaaccctt ccagattcag tttcaccgcg tatgcccagc
    55621 gcagaaccgt aaacagatag gcatcagcaa ttgtaaatcg ttgcccgcag atccagtgct
    55681 catccttcag agcatcgttc acatattgca gcttcttctc cagctgcgcg cgaactgttg
    55741 gtttgtactc ttccggtgta tcagggcgaa acagaggtgt gaagccttta tgcagctcgg
    55801 tggcgatgta attcagccat tcgatggttt tatagcggga aatactgttt accggtgcca
    55861 gcaactggcg gtcggggacg ctgtcggcaa gatactgcat aattgctacg ccttccgtca
    55921 gcaaagtacc atcgtccagc agcaatgcag gcacttgtcc cttagggtta acggcaaagt
    55981 aatcgtcacc gttttcgaga cgttttttca ttaaatccac actgacgagc gtaaaatcct
    56041 ttccgctctc acgcagggtg atatgggaag cgagagagca ggcgcccggt ttgtagaaca
    56101 atttcatcgg taactccttt tgtctgtggt ttaaagtatg gtagtgcgtt gctgaacaaa
    56161 aaaaaagccg ctaacgaaaa gttagcggct tgtaaaagag tttccctgaa ttttacgcta
    56221 cagcagcttt cgccgctttg tctgcagcgt catcctgcgt catgcggtgc agtttcggcg
    56281 cggtcagcag catcagtact gcaataacgg cagtagcaac accaatctgc aagaatacgc
    56341 gaccatagac ttccagtgac atcagtggat cggtaacgtt atccggcaca gccatcatac
    56401 ccgcaacata accaccaatc aggtttgcac cggcagtggt caggaaccag ctacccataa
    56461 tgaagcccat cagacgctgc ggaacgagtt gtgcaaccat tgccagaccc agaccagaga
    56521 tcataagttc cccgatactc tgcaggccat agcttgcgac cagccagctt acagacacga
    56581 tacctgcgtc agacgcgaat tttgcaccca gcggcagaat caggaacgca ccagaacaca
    56641 tcaccatacc gattgcaaac ttagttggca tcggcagggt atcgcccatc ttgttataga
    56701 tagcggccag aatcgggcta ccaatgatga tccagaacgg gttcagtgcc tgatactgct
    56761 caggttctac ggccaggccc agaatggtgt gttcaacgtt acgaatcgca aagaagttca
    56821 gtgacgttgg catctggctg tacagcacga agaagataat ggcttcgagc atcaggatga
    56881 aggcaacgat cattttacga cgcgcagcac ctttcatcgc gaaggcttct ttaccgaaga
    56941 taaccacgat accaaaggca acaacgccca gcgccatacg cgcaacttcc tgattgtgaa
    57001 gcagccaggt ggcgatagcg atcagtgcca caacaccaat aatggtcagc agcaggttac
    57061 ggtagttgat aggctcgaag tctggttttg aaccgtactg tttaacccag cgttggcaga
    57121 aggcgaagtt aacgatagtg atcagcaggc ctacaacgct caacgcaaac gcaacactcc
    57181 agccgtattt cgcggccagc cacggggtgg cgatcataga gaagaaagag ccgatgttga
    57241 cggacatgta gtacatggtg aatgcaccgt ccagacgcgg gtcgtttttc tcatagcatg
    57301 tagaaagcag agaagacggg ttagctttaa acaggccgtt accgaccgca atagccgcca
    57361 tacccatata aacgataccg gcgtcgtgac cagaccaggc caccagagca taaccaatcg
    57421 ccagcacaat agcgccaagc ataattacgc gtttagtacc cagtaccttg tcacctaacc
    57481 agccgccgat agcgaccaga ccataaacca gggcactaaa ggaagagaaa agggtgattg
    57541 aatccgcttc agacataccc agttgtttaa ccaggtaaac agccataatt ccttgtaggc
    57601 cgtaataacc aaaacgttcc cataactcaa tcgagaagat gagatagaac gccttcggtt
    57661 gtttgaaagc gttcaaactg acgctttcag ttggtttttg gtttgcagtg gacactttta
    57721 cctctttttt tacatcccat attaacgggg gtgctttctc gcgttatgcc taaaaaacat
    57781 acgcgcaatt gttatagtgg gaggggaaac ggcaggtaat gttcactatc ttgcactttc
    57841 agacaagtcc tttgtaataa tctgttacat ataactgagg cggggaattc aaccattccg
    57901 ggaaatgtta tccagcgtta aatttttcaa aaaacgtaac ggcagatttt ttcactaccc
    57961 tgagaggggg atgatggctt aacggcgata tgttctgcta tttagcgttt ttcctagtga
    58021 gatagtccag tttctgaaaa atagccagtg taatgttttg taggtcaata tttgttgcgt
    58081 gtgtaaattt aaatgatttt aacctagttc ttgcaatgtt tttacattgc cacagcatcg
    58141 tgatcttgat cacgaatgaa tagaaaattt cgctattaaa aaaacaatta acctgcattt
    58201 ttggttatcc gcaaacggat tacctgatga taacgctaag caatggcatc attgacgtta
    58261 aaaagatgtt ttaaaagagg ataaagaaag gttatcaatg gggtaatcgg tgttacccct
    58321 tttcttcaga tgtcaacttt ctctttgtat tcacaaagat cttcaataat acaagagcca
    58381 cagcggggct tgcgggcaat gcaggtataa cgcccgtgca ggatcaacca atggtggcag
    58441 tcgactttaa actctgcagg aaccactttc agtagctttt cttctacctg ttcgacgttt
    58501 ttccccggcg caaattgagt acgattacaa acgcggaaaa tgtgcgtgtc gacagcaata
    58561 gtcggccagc cgaatgcagt gtttaatacg acgttggctg ttttacgacc tacgccaggc
    58621 agggcttcaa gcgcagcacg atcttccgga acctcgccat tatgttgttc cagtaagata
    58681 cggcaggttt tgatgatatt ttctgctttg ctgttataaa gcccaatggt tttgatatag
    58741 gttttcaccc cttcgacgcc cagttcaagc atcgctgcag gtgtattcgc caccgggtag
    58801 agtttcgccg tcgccttatt aacactgaca tcggtcgcct gagcggaaag cagcacggca
    58861 atcagcaatt caaaaggcga actgaaatta agctcggtgg tgggatgagg attgttctca
    58921 cgcaggcgag tgaggatctc caggcgtttt gctttgttca tcagacattc cctgtttcac
    58981 cgtttggcaa tgcacgttcg gcagctgctt cagtacggcg ctttttcatt ttttcatcaa
    59041 tcaggtattt tcctgccagc atcagtccca ggccaataaa tgcacctggt ggcagcatcg
    59101 ccagcaggaa aggggagtcg gtgtggaaaa tctccacgcg taatactttc gcccagctac
    59161 ctaacagcgc atctgcaccg tcaaacaacg tgccattgcc gataatttcg cgtagtgaac
    59221 ccagcacgaa catggcgcag gttgcgccca taccaattga aaagccgtcc agtgccgaaa
    59281 gcgccggacc ttttttggcg gcgaaggctt cagcgcggcc cacaacgata cagttagtga
    59341 caatcagcgg aataaaaatc cctaatgatt gatacaggcc taaggcgtag gcgttgatca
    59401 gcatctgtac agcgctgacc accgaggcga tgatcatcac gtaaatggga atgcggatct
    59461 cggctggcgt ccagtgacgc agcgtcgaaa tggtcaagtt ggtcagcgtc agtaccagcg
    59521 tagtcgcaag tcctaaaccc agagcgttag tggcagtgga cgtgaccgcc aatagcggac
    59581 agaggccgag cagctggacc agcgcagagt tgtttttcca caacccctga acaataacgt
    59641 ctttaatttc gctcacgctt tattctccac aggcaggaag ttgagaaagt tgtgacggta
    59701 acgtctgagc gtacaatccg gcgcgtttta ccgcattaac caccgcgcgg ggagtaatcg
    59761 tcgcgccggt gaactggtcg aaatcaccac catctttctt caccgcccag tgcgcatcat
    59821 ccgcaccact gattttttta cccgcaaaat gggtgatcca gtcagaaagg cgcagttcga
    59881 ttttatcgcc aagccctggc gtttcgtggt gctctgtcac gcgcgtgcca agtaccgtgc
    59941 cgttaaaatc ggctcccacc agcagctgaa tcgcaccgga atagccatct ggcgcggttg
    60001 tttccagaac ggcggctacc ggtttgtcat cctgtttggc gatgtaaacc cgatgctcac
    60061 ctttacctaa ctctggcgca gtgaccagat agcaactctg tgccagcgca ttgttatagc
    60121 gttcggctgg cagcacctga tcaaataacg ccttttgttg cagactggcc tgttcagcaa
    60181 tcgtcgtttt ggtcatctgg ttgatggccg cagttaaccc tgttgaaccc gctgcaaata
    60241 gcgccaacgt aatgccgtgt tttcggatag ttttcagcat ggtttaccct ttgcgatggc
    60301 cgtagacgcg cggacgcgtg tagtaatcga tcagaggaac cgtgatgttc gccagcagga
    60361 cggcaaaagc aacgccgtca ggatagccgc cgaaactgcg gatcaaccag actaataagc
    60421 ccgccagcgc gccgaaaata agacgaccac gattggtcgt agaagcggta accgggtcag
    60481 tcaaaataaa gaatgcgccg agcatggtcg caccagacag cagatgaatt tgcggtgctg
    60541 ccagagtatc tggtgagaac aaccagccca acgttgcgca taacgccagc gttactaaga
    60601 agctgagggg aatatgccag cgaatcgctt tctgccatag caaccacacg ccgccagcca
    60661 gccaggcgag atttacccat tgccaaccag cgcccgccag cataccgctg tagatcggat
    60721 attgcataat ctgttcaacc gaatgaccgg cacggacaga ggttttaaat gtatccagcg
    60781 gtgtcgcctg actaatgcca tcaataccta agcgtagcgt gttcatatca ccaccactgg
    60841 cggtatgacc gctgaaaata acctgtatgg cgtcgataaa accagggatg ttgaccgcaa
    60901 tttcatgcgg cggtaaccag ctggtcatct gcaccgggaa ggagatcagt aagaccacat
    60961 aaccaatcat tgccggatta aacgggtttt gccccagacc gccatacaac tgtttagcga
    61021 tgatcaccgc aaacaccgta cccagtacga ccatccacca tggcgcgagg gggggaatac
    61081 ttaccgccag caataagcct gtcagcaatg ctgagttatc tttcaacgtt gcggctaccg
    61141 actgcttgcg tagtttgagt acgagagctt cggctaacag agcactgacc gacgccaaca
    61201 ggatctgaac gagagtaccc caaccaaaaa accacagttg cgctgcgatt cctggcacgg
    61261 ctgcgagcaa caccaacagc ataatgcgcg atgtttggcg ctggttatgg gtataagggg
    61321 agctagctat tctgaatacc atttagtcct cgtttacaac cttttgctgg gcggcttttt
    61381 tggcctgaac gcgggcaata gccgcagcaa ctgccgcttt gcgcggatca atctgttctt
    61441 ctggctccgc attagcctgt tgctgctcca gcttgcgtgc tttggcgcgg gcaatagcgg
    61501 cttcgacggc ggctttgcgc ggatcgacct gttcttctgg ttccgcatta gcctgttgct
    61561 gctccagctt gcgtgctttg gcacgggcaa tagcggcttc gacggcggct ttgcgcggat
    61621 cgacctgttg ttctggctcg gcattagcct gttgctgttc cagcttgcgt gctttggcac
    61681 gggcaatagc ggcttcgacg gcggctttgc gcgggtcaac ctgttgttct ggctccgcat
    61741 tagcctgttg ctgctccagc ttgcgcgctt tggcgcgggc gatagcggct tcgatggcgg
    61801 ctttgcgcgg gtcaacctgt tcttctggtt ccgcattagc ctgttgctgc tccagcttgc
    61861 gtgctttggc gcgggcgata gcggcttcaa cggcagtttt acgtggatca gcaacggttg
    61921 ctgcgtcgtt agtttgctgc agttctgcct gtttcgctct ggcttgcgct ttacgggctt
    61981 cccgtgctgc aataattgca ctgttatccg ggcgttcgcc cgctttaatc acaataggct
    62041 gtgtagcctg ggcctgtttc tctttcaccc gcgccagagc ggcagcaatc gcatctttat
    62101 ctttggctgc aggttgaacg gctgcgctct tatgtcgttc aaggcgagcc gctttttcgc
    62161 gctcaaggcg agcctggcgc gcttcgaaac gcgctttggc ttctgcggcg cgcttttctt
    62221 cctgacgaat agccgcaatt tcagcttttt cctgacggaa atattgcacc aggggaatat
    62281 tgctcgggca aacccacgcg caagccccac attcaatgca gtcggcaatg ttatgtgtgg
    62341 tggctttatc gtgttgctga cctttgctga accagtacaa ctgttgcggc aaaagatctg
    62401 cagggcaggc gtcagcacag gcgctacaac ggatgcaact ttgttcttcc tgtggttcgc
    62461 caagttcatt ggcagaggga gccaaaagac agttggtaat ctttacgacc gggacatcca
    62521 gccacggcaa ggtaaagccc attagcgggc cgcccataat caccatttga tcggcagagg
    62581 ggcagaatcc ggcatcattc aataaatgac gcactggcgt acccagccgt gcccagacgt
    62641 tgcccgggcg agcgattgct tcgccagtca gggttacgac acgctcggta atcggctcgc
    62701 catcaataac ggcacgtttc actgcataag cagtgccgac gttttgcatt aatacgccga
    62761 tatcggatga acgcccgcca tgtggaacct gcttcccggt cagaatgtag gttaattgtt
    62821 tagcaccgcc agaaggatat ttggttggaa tcacccgcag agaaatatcg tgagagtccg
    62881 ccagcaccgc gcgcagcatg gaaatcgcct gcggtttgtt atcttcaatg ccgataagaa
    62941 tttcgcgtgg ctgcagaata tgcgcaagaa tgcgaatacc ctctacgacc tgagccgcgc
    63001 aatcctgcat caaacggtca tcggcggtaa tgtacggctc gcactcagca gcgttgataa
    63061 tcaacgtttc aatcttatct ccgccgccct gcaatttaac gcctgtcggg aatcccgcac
    63121 cacccagccc ggcaacacca aactgatgaa tgcgctcgat taactcttcg cgactgcgag
    63181 agcgataatc gtcccagccg tcgcgcggga tccagcagtc ttcgccatcg gcatcaataa
    63241 tcacgcttaa ttcagctaaa gctgaaggat gagccgtaga gtggggcgca atagccgtaa
    63301 cggtacccga ggtgggcgcg tgaaccggca gcattttgcc gcgtccacgg gtaagcggct
    63361 ggccgcgcag tactttatcg ccgacgctaa cgcacaactc accttcagcg ccaatatgtt
    63421 gtttcagtgg tatgacaaaa cgctgcgcca gtggtacctg gcgcaggggc gtaccgttgg
    63481 actgggtttt catctccggt ggatggatgc cgccgttgaa atcccagatt ttattttttc
    63541 tgaatgcaga gaataactta agcatggtgt tccacgggaa tgatacgcac gggaatggtg
    63601 ttcagatccc atttccagga gtcaggtgtt tctgcaaccg gttgcaacga gatgcagtgc
    63661 gtcgggcacg gatcaacaca taaattgcag cccgtacaga gatcactcat taccgtatgc
    63721 atggcgcggg tagcgccaac gatggcgtct accggacacg cctgaataca tttagtgcag
    63781 ccaatacagt tattttcatc aataaccgcc accatctgcg caggcgttag ctcttgcgct
    63841 tcgccatcca gcggctgtgg ctcgacatta agcaactcag caatttttag catcacagct
    63901 tcgccacctg gggcgcaacg gttgattttt tcaccgttac agctgatggc ttccgcgtag
    63961 gggcgacagc cgggataacc gcactgacca cactggctct gcggtaagat ttcgtcaatt
    64021 ttctcaacga ccggatcgtc ttccaccgca aaacggcggg aggcataacc cagaatggcg
    64081 ccaaacgcca ggcccagcag gctcacggcg gcaacggcaa tccagatagc attcattaca
    64141 acttcaccaa accactaaag cccataaagg ccagagacat aagacctgcg gtaattaacg
    64201 caatggcatt accgcgaaaa ggtgccggga catcagccac agcgaggcgt tcgcggatgg
    64261 cggcgaagag caccatcacc agcgagaaac cgacagcggc ggaaaaaccg tacagcgccg
    64321 actgcaagaa attgtgcccg agattgatat tcagcaacgc cacgccgagc acggcacagt
    64381 tggtggtgat aagcggcaaa aaaatcccca gcagacggta aagcaccggg ctggttttgc
    64441 gcaccaccat ctcggtgaac tgcacaacca cagcaatcac cagaataaac gccagggtgc
    64501 gcaggtaaat cagattaagc gggatcaaaa tccacgtatc gataagccag gcgcaaatag
    64561 acgccagcgt cattacaaac gttgttgcca gccccatgcc catcgcggtt tccagctttt
    64621 tggaaacccc cataaacgga cagagaccga gaaacttgac cagtacaaag ttattgacca
    64681 gtacagttcc gacaaacagt aacaggtagt cagtcatttt tcggcctgaa ataaaaaagc
    64741 cgcctattat ccgttaatcc agagcaggcg acaacaggtt aactgtaagg ttattacgga
    64801 ttcacaaacg tcgctttcac ccgcgacgag cgtttgaaat aggggacgat caatgcggtt
    64861 gccaacaaag taaacagcaa ctggcgaacg gctatgccat cttctacggg tgaaaaagcg
    64921 aacgctttta ctgccagcaa tacggaaata agcagccaga taatatagtg tttaggaaca
    64981 caacgccgac gtttaaagaa agcgatggtc aaccacagtg tgtaatacca catggcgata
    65041 gcggtaataa aagaaacgcc ccataagatt tgtgtcgtca gtgcttgtcc gccgagcgtt
    65101 tgaaatgttt gcggagaaga taacgcagcg gtatacagca acaacgccag cgtcgtactt
    65161 aacagagcga ctaaaagcca ggccaatggg ccaagtaacc agcctccaat acgttgtggc
    65221 gttgtggtgg tcataggttc tccagaatag cgacgcaaac aggcaaatct aattttaggg
    65281 gcgttattat aaggctttta taaccgatcg ctactttctt tactggacat agtgccagac
    65341 ggacttcggt acctggccga ggtcaaacaa acgcccgcca gaaaccagct ctgcgcggcg
    65401 gtgatcggca gcacgataca tattgatcag ttcctgatca tccgtcagag tgtaattaag
    65461 atggtcgtag agtttttcca gactttcgag tgaactgatt ttgcgaaatt ttaataagta
    65521 gtcctgaaca gtcataaaag gtccataaaa taattaatac caaaggagta ggtattatta
    65581 gtgatgataa aatttcacca aaagtgaacg cgtgtgttat tacaataata agaatgcgct
    65641 gatggcaaat attcagagat gaaaaactgc tctgaaaaga gtaacgcgct ttactatccc
    65701 tgacaatcac caacaacatc gaacaagata ataaattcct ggtttaatat ccgacaagtg
    65761 aaaacatgca cccggacggg cagcatgtcg ctctacaagc gcagagctta cttgtgttgt
    65821 accgtagtac tctgttcagg tggctgatag ttgtcaatgt gactcgccac gccaagaaga
    65881 atgactgaaa cgacaagaac gatccaacct gttaattcaa taagacgatt cattacagcc
    65941 cacatctctg ttgattgatc cattaacttc agggggtaaa tgttacttag caataatagc
    66001 tccagcaaga tttttactga ggtttttgcg atatttagct tttgtcgttg gaaaattcgc
    66061 tatttttttg acttaagtta aacaacatcc cttattgctg gcaggttatt aaactgttga
    66121 gcgagggtaa aggatagtgt caaatagcca tcatacttca atgagaggca atgacatgag
    66181 cgacaacatc cgtgttgggt tgattgggta tggttatgcg agcaaaacct tccatgcgcc
    66241 cctgattgcg ggcacgcccg ggctggaact ggcggtaatc tccagcagcg atgaaacaaa
    66301 agtaaaagcc gactggccaa cggttgcggt tgtctctgag ccgaagcatc tgtttaacga
    66361 tcccaacata gacctgattg tcattcctac acccaacgat acccatttcc cgttagccaa
    66421 agcggcgctt gaggcgggta aacatgtggt cgttgataaa ccctttaccg tgacactgtc
    66481 acaagcgcga gagctggaag cgctggcaaa aagcctgggg cgtgtgctgt ctgtattcca
    66541 taaccgtcgc tgggatagcg atttcctgac gctaaaaggt ttgctcgcgg aaggcgtact
    66601 gggtgaagtt gcttactttg agtctcattt tgaccgcttc catccgcagg tgcgcgatcg
    66661 ttggcgtgaa cagggcggtc ctggcagcgg tatctggtac gatttagcac cgcatcttct
    66721 tgatcaggcc attacgctat ttggtttacc ggtcagcatg acggttgatt tggcacagtt
    66781 acggcccgga gcgcagtcga ctgattattt ccacgccatc ttgtcctatc cgcagcggcg
    66841 agtcatttta cacggcacca tgctggcagc cgctgagtca gcacgttata tcgtgcatgg
    66901 atcccgaggc agttatgtga aatatggcct cgatccacag gaagaacgtc tgaaaaatgg
    66961 cgagcgtctg ccgcaggaag actggggcta cgatatgcgt gatggcgtac ttacccgcgt
    67021 ggaaggtgag gaacgtgtcg aagaaacgct gttgacagta ccagggaatt atccggctta
    67081 ctatgcggct attcgtgatg cgttaaatgg cgatggtgaa aatccggttc cggcaagtca
    67141 ggcaatccag gtaatggagt tgattgagct gggcatcgaa tccgccaaac atcgcgcgac
    67201 gctgtgcctt gcgtgaaaag aggatggtgc aattagcacc atccattttt gttacttcgc
    67261 ggcgactttt tctcgcagtg cgcgtttttc ctctgcgctg aggaaagcca tttccagacc
    67321 attaatctgc gcctggcgga tttgctcgcg ggataaccca gcagccggcg cggcaacggt
    67381 atattcgtga atgatatcca ctccctgtac gccgggatcg tcagtgttaa tgctggcacg
    67441 aatgccatgc tcaaggaaca ttttcagcgg atgtgccgcc agctctgcca cggtgctggt
    67501 ctgaatattg gaggtcagac aggattcaat accaatttgc tgctcggcga gaaaatccat
    67561 cagcgcccga tcttcaatgg cttttacgcc atgtccaata cgctctgccc ccagttcacg
    67621 aatcgcctgc cagatgcttt ccggcccggc agcttcgcct gcatggacgg taatatgcca
    67681 gcccgcatca cgcgcgcggt tgaagtgaga aagaaacaga cttcccggga aaccaagttc
    67741 atcaccggct aaatcaagtg cggtaatctg gtcacggtgg gctaaaaagg cctccagctc
    67801 ttgctgacag gctgcttcac cgaaggtccg gctcataatg ccgataagct tcgcctgcac
    67861 accaaaggtg cggcaacctt cacgtacgcc atcgatcacc gcttcgacaa cacccgctac
    67921 aggcagctga tgtgccattg ccatgtagcc cggtgaaaaa cgcagctcga catagtgcag
    67981 gccgttacgg gctgcatctt caatgttttc aaatgccacg cggcggcaag catcaagaga
    68041 ggcgagaact ttaacgcccc agtcaagttt agtcagaaag ctcaccagat cgggttcgtt
    68101 ggcaatgacc tgaacgtggg gaatcagtgt ttccagggat tgtgcaggaa tcgagatatt
    68161 atactggcgg ccaagttcaa gaatggtctg gggacgaatg ttgccatcaa ggtggcgatg
    68221 gatatcagtt aatggcaggg tggtatcaat catggtcgca ctctttttct ggatataaaa
    68281 gtgcgcacca ttataaaaac aaagcagggt aaaaatccac gattgcgcaa cgatttttta
    68341 cgttgcgcaa ttggggttaa cgaacagcgc ggatggcgtt aattaatcca gcaacacctt
    68401 tttccagttt cgaacgcggg cacccggcat tgagtcggac aaaaccacga ccttcttcac
    68461 cgtaggtata tcccggcatg atcgcgacct tttcttgctc gataagcgct ttttgcaacg
    68521 cgttgtcgtc aatgttcaat ggacgtagat caagccaggc cagataagtg gattgcggga
    68581 tctgccagtt gagttcagga aacgcagcgt tcattttatc tgcgatatac gtcaggttat
    68641 ctttcagata gacgcgtaag gcatccagcc acggcgcgcc ttgctgatag gcggcgatat
    68701 gagcagttaa cgccagtacc gaaggagaag aaagcccatc acgtcctttc agtgccgata
    68761 aataggcatc gcggctactg ctattttcta taatcccgta agcaccggtc agggcgggaa
    68821 tattgaaact ttttgatccc gacgttagca acgcccagtc tccgcgcgcc acattacacc
    68881 agggaatatg cggctgctcg ccccaaacca tatccatatg gatttcatcg gaaataaccc
    68941 gcacaccatg acgctcgcac aggtcagcca tgatctccag ctcatcgcac gtccacactt
    69001 tcccggtagg attctgtggg ctacacagga gcataatttt acattctggt ttcgccagca
    69061 cggcttccag cttgcccata tcgcaaaacc agccgtcagc ctgcttctct aaagcaacgg
    69121 gcattactgt gcgctggtta ccttcaatgg ccttgtaaaa tgcgtcatag gcgggtgtgt
    69181 ggatcaccac gccttcacct gtttcagacc actgacgaat cagttctgaa accatataga
    69241 tgacagaagg gccatacacc accgactgag gatcgatggc ggtgtaatgc tgggtggaaa
    69301 accagtgggc aatagccgcg agaaactcat cgtttttcca gcggctgtag ccaaacacgc
    69361 cgtgcatcag acgctgattc agcgcctcga taatgcaggg ggcagtggca aaatccatgt
    69421 ctgaaatcgt gaacggtaac aggtcagcag tgccgaaacg gtcggcgaca taatcccact
    69481 gcgtacacca tgtgccatga cgatccacga cctttgaaaa atcgaacata tcttatcctt
    69541 atgcctggac agtatgcatc agaccggcca tttcatcttt tactgactga acttgtggcc
    69601 cgataacaac ctgcaggtta tgttgattaa gttgtactac gccaattgcc cgattgtcct
    69661 tcagtgcctg cacattaaca agcgacatat cttttacaga caaacgcaga cgggtaatgc
    69721 agttatcgag actgacaata ttgtcggctc cgcctaaggc ttcgaggatt gccggaacgt
    69781 tgtaacctga tttacccggc gcaccggcaa cggctttttc gattgaactg gcaacttcac
    69841 tatcgcgccc cggggttttc agattgaagc gggtgatagc gaaacggaag atgacgtagt
    69901 aaacgacaaa ccatattgcc gccactactg gcaccatgta ccacttggtt gacagaccat
    69961 gcaaaatacc gaacaccaca aagtcgatga tattgccgtc ggtattaccg atggtgacgc
    70021 cgagcacaga catgacagtg aagccgaggc cggttaacag cgcgtggatg acatacagaa
    70081 ctggcgctac gaacaggaac aggaattcca gcggttcggt cgtgccgcca acgacacagg
    70141 cgatcaggcc agaaatcagc agacctttaa ttttatggcg attttccggg cgcgcacagt
    70201 gatacatagc taacgctgca cctggcagac cgccgagaaa cgcaggcatt ttaccttgcg
    70261 aaaggaaacg cgtggcgctt tcagaaaaac cgtgagtggt cgggcaactc aattgcgcct
    70321 ggaagatggt cagtgcaccg ctgacggttt gaccgcagac ttcctgcgtg ccgcctgcgt
    70381 cggtaaagcg aattaatgcc accagaatgt gatgcagacc aaacggcaac agcagacgtt
    70441 caccggtacc aaacagcatc ggtccgaaat cacccgcgct gttgatcata tggcctaatc
    70501 cgctaatacc catggcgaaa attggccaga ctaatggaat caccaggccg acaagaccca
    70561 tcaccagcga ggagatgatt ggtacgaagc gcgtaccgcc gaagaatgcc agcgcatctg
    70621 gcaggcggat attatggaaa cgctcatgca gcatccagac gataataccg gcgatcaccg
    70681 caccgaggat cccggtgtcg atcgactgga tcccaagaat gctctgaatg ttattggctt
    70741 tcagaaccgc ggcgtccgtg gttggcagaa tgcctttatt ggtcaaccag aagtttaccg
    70801 cgaggttcat taccgcataa ccgacgaagc cagcgaatgc cgctacgcct ttgttttcgc
    70861 gtgccagacc cagcgggatg gcgatacaga acatgactgg caggaaacta aaagcaaacg
    70921 agccaatctt actcatccag gtaaagatag cctgcaacac ggggttgccc aggaccggga
    70981 tcagggtgat gacatcatgg ctgctaagag aactaccaat gccgagcata atgccgcaga
    71041 acgacaataa tgccacgggt aacatgaagg ttttgcctaa ctgctggaag aattcccaca
    71101 gcgtgacttt cggtgctgtt ttcgccgtca taaaacgact cctcgtagag aacaatctgg
    71161 attcagtaaa ttgcgcgaga agataaaacg ttttatcaaa ttttagtgag gcataaatca
    71221 cattacgcaa cgataatagc gggtataaga taaataaaag gtaaaacgtt ttatctgtca
    71281 cataatcagg gagtaggtca tctgcatggc taccgccaaa aaaataacca ttcatgatgt
    71341 tgcgctggct gcgggcgtgt cggtaagcac cgtttcgctg gtgctaagtg gcaaagggcg
    71401 aatctctacc tccacaggag aacgcgttaa cgccgccatt gaagagctgg gatttgtgcg
    71461 caatcgtcag gcgtcggcgc tgcgcggcgg gcaaagcggc gtcattggtt tgatcgtccg
    71521 tgatttatct gcgccgtttt acgccgaatt aacggccgga ttgacggaag ctctggaagc
    71581 gcagggacgg atggtttttt tgcttcacgg cggtaaagac ggcgagcagc tggcacaacg
    71641 gttttcactg ttactgaatc agggggtcga tggtgtggta attgccgggg ctgcaggaag
    71701 cagcgatgac ctgcgacgga tggcagaaga aaaagctatc ccggttattt tcgcttcccg
    71761 tgccagttat cttgatgatg ttgatacggt tcgcccggac aacatgcagg ctgcacagtt
    71821 gttgacggag catctcattc gcaatgggca tcagcgtatc gcctggctgg gagggcaaag
    71881 ttcctcatta acccgggcag aacgggtggg gggctattgt gcaactctac taaaatttgg
    71941 cctgccgttt cacagcgatt gggtgttgga gtgctcttcc agccagaagc aagccgcgga
    72001 agctatcacg gcgcttttac gtcataaccc gaccatcagt gctgtggttt gctataacga
    72061 aactattgcg atgggggcat ggtttggttt gctgaaagca gggaggcaaa gcggggaaag
    72121 cggagtcgat cgttactttg agcaacaggt ttcgctggcg gcatttaccg atgcaacgcc
    72181 taccacactt gatgatatac ccgttacctg ggccagcacg ccagcgcggg aacttggtac
    72241 cacacttgcg gatcgcatga tgcaaaaaat cacccatgaa gagacgcatt cacgcaattt
    72301 tattattcct gcccggctca ttgcggcgaa ataatcctct ctttatctgc tatacctggt
    72361 agtgtccttt cctcaaggtt aatgataaaa aatgtggcac acaggcggtg ccttttatct
    72421 ttactgaagt tcacaggagg tttatgtgtt taattctgac aacctgagac tcgacggaaa
    72481 atgcgccatc atcacaggtg cgggtgcagg tattggtaaa gaaattgcca ttacattcgc
    72541 gacagctggc gcatctgtgg tggtcagtga tattaacgcc gacgcagcta accatgttgt
    72601 agatgaaatt caacaactgg gtggtcaggc atttgcctgc cgctgcgata ttacttccga
    72661 acaggaactc tctgcactgg cagactttgc cgtcagtaag ctgggtaaag ttgatatcct
    72721 agttaacaac gccggtggcg gtggtcctaa accgtttgat atgccaatgg cagattttcg
    72781 ccgtgcttat gaactgaatg tgttttcttt tttccatctg tcacaacttg ttgcgccaaa
    72841 aatggaaaaa aatggcggtg gcgttattct gaccatcact tctatggcgg cagaaaataa
    72901 aaatataaac atgacttctt atgcatcatc taaagctgcg gccagtcatc tggtcagaaa
    72961 tatggcgttt gacctgggtg aaaaaaatat tcgggtgaat ggcattgcgc cgggggcaat
    73021 attaaccgat gccctaaaat ccgttattac accagaaatt gaacaaaaaa tgttacagca
    73081 cacaccgatc agacgtctgg gccaaccgca agatattgct aacgcggcgc tgttcctttg
    73141 ctcgcctgca gccagctggg taagcggaca aattctcacc gtctccggtg gtggggtaca
    73201 ggagctcaat taatacacta acggaccggt aaacagccgt acgtgttgtt taccgggata
    73261 gcgtgaacaa ctcatcaacg tctctgcgaa acaactgaca gccaaatcac ggctattggt
    73321 taaccaattg ctgggtgaaa agtatacgaa tagagtgtgc cttcgcacta ttcaacagca
    73381 atgataggcg ctcacctgac aacgcggtaa actagttatt cacgctaact ataatggttt
    73441 aatgatggat aacatgcaga ctgaagcaca accgacacgg acccggatcc tcaatgctgc
    73501 gagagagatt ttttcagaaa atggatttca cagtgcctcg atgaaagcca tctgtaaatc
    73561 ttgcgccatt agtcccggga cgctctatca ccatttcatc tccaaagaag ccttgattca
    73621 ggcgattatc ttacaggacc aggagagggc gctggcccgt ttccgggaac cgattgaagg
    73681 gattcatttc gttgactata tggtcgagtc tattgtctct ctcacccatg aagcctttgg
    73741 acaacgggcg ctggtggtcg aaattatggc ggaagggatg cgtaacccac aggtcgccgc
    73801 catgcttaaa aataaacata tgacgatcac ggaatttgtt gcccagcgga tgcgtgatgc
    73861 ccagcaaaaa ggcgagataa gcccagacat caacacggca atgactgcac gtttactgct
    73921 ggatctgacc tacggtgtac tggccgatat cgaagcggaa gacctggctc gtgaagcgtc
    73981 gtttgctcag ggtttacgcg cgatgattgg cggtatctta accgcatcct gatcctctct
    74041 ctctttccgc gggctggtga caactgtgcc cgcgtttcat atcgtaattt ctctgtgcaa
    74101 aaatcatcct cccagggatc ggagaatccc acctaaatat tcatcgtagc aatatatcat
    74161 gagggtttat cgctcccaat atgttcgaac gaacgttcga ttgcttattt tgtggcttct
    74221 gtcaacgctg ttttaaagat taatgcgatc aatatcacgc tgtgggtatt gcagtttttg
    74281 gttttttgat cgcggtgtca gttcttttta tttccatttc tcttccatgg gtttctcaca
    74341 gataactgtg tgcaacacag aattggttaa ctaatcagat taaaggttga ccagtatttt
    74401 tatcttaatg aggagtccct tatgttacgt cctgtagaaa ccccaacccg tgaaatcaaa
    74461 aaactcgacg gcctgtgggc attcagtctg gatcgcgaaa actgtggaat tgatcagcgt
    74521 tggtgggaaa gcgcgttaca agaaagccgg gcaattgctg tgccgggcag ttttaacgat
    74581 cagttcgccg atgcagatat tcgtaatatc gggtcagcga agggccgtta caagggatga
    74641 atttctttct tgctgccgat aaagggcggg aaaagcgcga tggcagtgcg ctgggcgatc
    74701 gcctgaatta ctgggatgtg aaaatgagta ttcagtatga ctttatgctg aagtaagaaa
    74761 aaacgccgga gagaaaaatc tccggcgttt tggctgtgaa ttactgctgc ggaatagcgg
    74821 gtacagccgg aacgtttaat gtcggcatcg caaacatacc cacgaaatct tccagtggca
    74881 ttttctgccc gtttaacgtt atctgaccgt tagcatattg caggctggtg gtgatggtat
    74941 tgtcctgcaa ggtggtcaga cggaacatct gccccattgc tgatgcacct tcaacttgct
    75001 gtttcgccag ttttttcgct tgatcttcct gataaccttc cagcttcgct acctgagtca
    75061 tcaactcagt tgccatatcc accggaatgg tcagtttcgc atccagagat ttaaccgagc
    75121 ggtccacttc ctgcgccagc gtttgcggcg cttctttagt tgttgccgga tctttcagga
    75181 acagcgacag attcagcgca ctttcaccct gactgttttt ccagcttagc ggcgcgatag
    75241 taatcaccgg atcgcctttc aacatcagcg gcagggcgct aaagaaggct tccgtcactt
    75301 tctcctgata aagttcggga ttgttggcaa tttttggctg tgccagcagc gcctgagttt
    75361 gcgcgttata ttgctggcta aactgatgcc aggcttcacc atcaatctgg ccgactttta
    75421 aagtcagctt gccgctgccc agatcctgat tctgtacctt caggctgttt agcgagtaat
    75481 ccagttggct attgatcgtt ttaccgtcat tgaccagatc cgatttaccg ctgatctcca
    75541 tgccttccag cagtgccagt tctttgcctt ccactgaaat ggtcattttt tccagtgaca
    75601 gtttttggtt tcctacgcgc tcaccaaaac ttgccagcgt gctggaaccg tcggttttca
    75661 gattattaaa ggtcaactgt actttctggt tgtattcgtt aactgcgtct atccgaccac
    75721 tttccgcctc tccggaaagg gagatagctt tgccgtctct gtccgcattt aactggaact
    75781 cgccgccgct aaaggcgact ttttcatcct tttgctcgta attcagcggc ttgagcgaaa
    75841 tatcggaact ggaatctccg ctgtaaccaa tgcgggagtt aatctcaaaa ggcgtttcac
    75901 cttttgccat atcaaacagt ggcttgctaa cttcgttatt aaccagcgtg gtttgaattg
    75961 atgccatcga cgggatcagg ttcagttttt ttagctgggc acgggggaag ggaccatgat
    76021 caaccgattc gttgaagatg acgctctgac cgcttttaat ccacggattt tctttcccgg
    76081 caatgggttt caccaacagt tgcagctgac tgctgaatac gccgcgatga tagttttgat
    76141 aactcacttc caggttggat tcaggagcgg tcagtttgag ttgcgcgttc gcctgcgcga
    76201 ccatgtcttc gagatgggtt tcaatcttct tgcctgtata ccatgcgccg cctgtccaga
    76261 ctacgcctag cgcaacaatg acgcctaccg ctaccagcga tttattcata atgattatcc
    76321 ataaaatgaa atcaggcgga ctggccgcct gaaggtgtta taagccttta ataagcttag
    76381 caagagatgt taattttttc agtaagctct tacagcttgt tgtaaacacg cgctaaacgg
    76441 ccgtggcctt tgacagtcac cggtgattcg ttggcggcaa taaacgctga ttcacccggt
    76501 ttaagctgta actgctgaga acctttacac agcgttgcat cgccttcgac gcagaacaaa
    76561 atggcggcac tctgctggct gatgttggtt tctttatcac taagatcatg cagcgagaag
    76621 gcaaaatcat caacaggaat cgggaagtcc agttctgcac cttgtttcac cggctgggtc
    76681 aacaactggt tagccggttt ggcttcgaac ttcacattgg caaccagttc cggaatatca
    76741 atgtatttag gcgtcagacc tgcacgcagc acgttatcgg agttcgccat cacttccagc
    76801 gccacgcctt gcaggtaagc gtgcggtgtt tcagcgaaca ggaacatcgc ttcgccaggg
    76861 ttcaatttca ccacattcag caatagcggg gagaacagac cgctgtcttc cgggtaaaat
    76921 tcagaaatta aacgaatcgt ttgccacggt tcaccctgct ggctgtcgag ggccgatttt
    76981 aaaatcgcca gcgcgcggga tttttcttca ccctgcatat tcaacaggct ggcgaacagt
    77041 tcgcttaaac gttcggcatc aggctgttgt aaaaagtgag caatcgccgg atgtgcacct
    77101 gcgaccggct ggagcaggga gacaatctcg gataaatcac gaaacgcgtt catcgcaagg
    77161 aaaggcgtca gcgcaaaaac cagctccggc ttgtggttag gatctttata gttacgctcg
    77221 gcggcatcca tcggaatacc tgcggcattt tctttggcaa aaccgatttc agaattgcgt
    77281 ttgtttggat gaacctgaat ggagagcggc tgtgctgcgc ataatacttt gaacaggaaa
    77341 ggcagttcgc caaagcgttt ggcaacggca tctcccaaaa gagtcgcttt atcactctca
    77401 atcacatcac gcagtgaaac gatatctccg gcggcattct gcacccgtga actgcttttc
    77461 ggatgtgcgc ccatccacag ctcggccatc ggctggctgg acggattttc cataccataa
    77521 agttcagtca acgccgtttt gctgccccag gcatagtttt gcactgagtt aatgagtttt
    77581 tgcatgatca atccctgttt aaatgtggaa attaatcccg ctattaaagc aagaatccta
    77641 cgggaagtaa cctggagccg caaaaagtcg tactagtctc agtttttgtt aaaaaagtgt
    77701 gtaggatatt gttactcgct tttaacaggg caacggaaca cccgcccaga gcataaccaa
    77761 accaggcagt aagtgagaga acaatgtcaa acaaaccctt tcattatcag gctccttttc
    77821 cactcaaaaa agatgatact gagtattacc tgctaaccag cgaacacgtt agcgtatctg
    77881 aatttgaagg gcaggagatt ttgaaagtcg cacccgaagc gttaactttg ttggcgcgtc
    77941 aagcgtttca tgatgcgtca tttatgctgc gtccggctca ccaacaacag gtggccgaca
    78001 ttctgcgtga cccggaagcc agcgaaaatg ataaatatgt ggcgctgcaa ttcctgcgta
    78061 actccgacat cgccgcaaaa ggcattctgc cgacctgtca ggataccggc accgcgatta
    78121 ttgttggtaa aaaagggcag cgtgtatgga ccggtggcgg tgatgaagcg gcgctggcac
    78181 gcggtgttta taacacttat atcgaagata atctgcgcta ctcgcaaaac gcgccgctgg
    78241 atatgtataa agaggtgaat accggcacca atctaccagc gcagatcgat ctttatgccg
    78301 ttgatggcga cgagtacaaa ttcctctgta tcgccaaagg tggcggttcg gcaaacaaga
    78361 cgtatctcta tcaggaaacc aaagcgttac tgacgccggg gaaactgaaa aattacctgg
    78421 ttgagaagat gcgcacgctg ggtacggcgg cctgtcctcc gtatcatatt gcgttcgtta
    78481 ttggtggaac ttctgcggaa acgaacctta aaacggtgaa actggcttcc gctaaatact
    78541 atgatgaact gccaacggaa gggaatgagc acggtcaggc attccgcgat gtggaactgg
    78601 aaaaagaatt gctgatcgaa gcgcaaaatc tcggtctggg tgcgcagttt ggtggtaaat
    78661 acttcgctca cgacatacgc gtgattcgcc tgccacgtca cggcgcatcc tgtccggttg
    78721 gtatgggtgt ttcctgctct gctgaccgta atatcaaagc gaagatcaac cgtcagggga
    78781 tctggatcga aaaactggaa cataatccag gtaaatatat ccctgaagag ctgcgtaaag
    78841 cgggagaagg cgaagcggtg cgcgttgacc ttaaccgtcc gatgaaagag atcctcgcac
    78901 agttgtcgca gtatcccgtt tctacacgct tatcgcttaa cggcacgatt atcgtcggtc
    78961 gtgatattgc tcacgccaaa ctgaaagagc ggatggataa cggtgaaggg ctgccgcagt
    79021 acattaaaga tcatccgatt tactacgcgg gtccggccaa aacgccggaa ggttatgcct
    79081 ccggttctct tggcccaacg accgccggac ggatggattc ttatgtcgat caactgcaag
    79141 cgcagggcgg aagtatgatc atgctggcga aaggcaaccg cagccagcag gtgacggatg
    79201 cctgtaaaaa acacggcggc ttctaccttg gcagtatcgg tggtccggcc gctgtattgg
    79261 cgcagggaag tattaagagc ctggaatgtg ttgaatatcc ggaactggga atggaagcca
    79321 tctggaaaat tgaagtggaa gatttcccgg cgtttatcct tgtggatgat aaaggaaatg
    79381 acttcttcca gcagatacaa ctcacacagt gcactcgctg tgtgaaataa acagagccgc
    79441 ccttcggggc ggttttttta catggcacga aagaccaaac atttgttatc aaatagtaaa
    79501 taataagtga gctaaaagtt gcttaacgaa agcaaaacag aaagaaaaaa ttaaacaggt
    79561 gaggagcagg ccatgaatac agtacgcagc gaaaaagatt cgatgggggc gattgatgtc
    79621 ccggcagata agctgtgggg cgcacaaact caacgctcgc tggagcattt ccgcatttcg
    79681 acggagaaaa tgcccacctc actgattcat gcgctggcgc taaccaagcg cgcagcggca
    79741 aaagttaatg aagatttagg cttgttgtct gaagagaaag cgagcgccat tcggcaggcg
    79801 gcggatgaag tactggcagg acagcatgac gacgaattcc cgctggctat ctggcagacc
    79861 ggctccggca cgcaaagtaa catgaacatg aacgaagtgc tggctaaccg ggccagtgaa
    79921 ttactcggcg gcgtgcgcgg gatggaacgt aaagttcacc ctaacgacga cgtgaacaaa
    79981 agccaaagtt ccaacgatgt ctttccgacg gcgatgcacg ttgcggcgct gctggcgctg
    80041 cgcaagcaac tcattccgca gcttaaaacc ctgacacaga cactgagtga aaaatcgcgt
    80101 gcatttgccg atatcgtcaa aatcggtcga acccacttgc aggacgccac gccgctaaca
    80161 ctagggcagg agatttccgg ctgggtagcg atgctcgagc ataatctcaa acatatcgaa
    80221 tacagcctgc ctcacgtagc ggaactggct cttggcggta cagcggtggg tactggacta
    80281 aatacccatc cggagtatgc gcgtcgcgta gcagatgaac tggcagtcat tacctgtgca
    80341 ccgtttgtta ccgcgccgaa caaatttgaa gcgcttgcga cctgtgatgc cctggttcag
    80401 gcgcacggcg cgttgaaagg gttggctgcg tcactgatga aaatcgccaa tgatgtccgc
    80461 tggctggcct ctggcccgcg ctgcggaatt ggtgaaatct caatcccgga aaatgagccg
    80521 ggcagctcaa tcatgccggg gaaagtgaac ccaacccagt gtgaagcatt aaccatgctc
    80581 tgctgtcagg taatggggaa cgacgtggcg atcaacatgg gtggcgcttc cggtaacttt
    80641 gaactgaacg tcttccgtcc gatggtgatc cataatttcc tgcaatcggt gcgcttgctg
    80701 gcagatggca tggaaagttt taacaaacac tgcgcagtgg gtattgaacc gaatcgtgag
    80761 cgaatcaatc aattactcaa tgaatcgctg atgctggtga ctgcgcttaa cacccacatt
    80821 ggttatgaca aagccgcgga gatcgccaaa aaagcgcata aagaagggct gaccttaaaa
    80881 gctgcggccc ttgcgctggg gtatcttagc gaagccgagt ttgacagctg ggtacggcca
    80941 gaacagatgg tcggcagtat gaaagccggg cgttaatctg caacatacag gtgcagccgt
    81001 ggaatgatca aacgaagcgg ctgcgcctgt ggtttataac ggtgctgcac attgtcggca
    81061 tcgtaattta acaactcacc aacgtctggc acgcccgcac cattatcccg attaatcagt
    81121 gcaatcagcg gtgtagggca ggcgtgttgc acttgttttt gatctccttt gtaccagacg
    81181 cgggcaatcg gctgcacctt caccggacgt ttgattttta acttcgcgtt ctgtggcagg
    81241 gcagcgatat cctgatactc tcgctccagt tttctttgcc actcctcgcg cgtccacggt
    81301 gcgacactgc gtggtgattt caggcttttt tccagctgtg ccaggacttc atcacgatgc
    81361 aaattcttaa tgatatgttt attagcccaa ccaaagcgta aagtggcggg gtcgtgcaga
    81421 acggtgagcg tgcggtaagc attaagggtg atcagccccg gcaaatgacg atgcacccat
    81481 tcaaaacgtg ccgcggtggg gagttctgat tcaaccgtga cgatatgctc gaacgtggtc
    81541 ttgagtttat tgatgtgctg aatatgactg accaacgctg cttgcgaaag gttatcgacc
    81601 tggtaacaca acacgccagg cagacggaca gcggccttgc tgctgcgatt ttcggactgt
    81661 tgttgaataa ataaatggcg gaaatgacgc aacgccagcg actgcgcgtc gttgccgaga
    81721 tgttgtttta cctcaatacg attaagcgga ttatgctcat cctctttttt tacctccggc
    81781 aaagagaaca cgcgggcaac caatagcttg tgttgctcaa gatgagcggc aaatgcagcc
    81841 agctcttgtt ccatctggcg aaaagtagtg ttgagtcggt ctacgagatc gtaacgcgcc
    81901 ataatattaa ccactttagt tacaacatcc ttattttata gcacaatggt ggtgacttga
    81961 ccaccgtgcg catagtgtca ggcagaggta aattgcggga tgttatgcca taacggccag
    82021 ctgaacgaga agcgggcacc acccagttcg ctggtgtcac aattagccgt accgcccatt
    82081 gccagtgcta tagagtggac aatggccagc cccagcccgc agccgccggt tgagcgatcc
    82141 cggctgggat cgaggcgaac aaaaggttca aagatatgtt cgcggttttc tggggcaatc
    82201 cctgggccat catcctcaac aattaatgtc gctctattcc ccgacagtag caggctggtt
    82261 tcaaccgttg aatgacagta gcgcagggcg ttattgagca aattatccag cacacgctcc
    82321 attaagcgca tatccaacgc cgcataatgg ccttgcgcga gcgtttttat ccgtaccgtt
    82381 ttatcgggcg ttactgcctg aatgtctgcc agatgcgttg acagccacaa cggcaggtct
    82441 ggttcgctaa gatgaagctc gttttgtggg cgatcgagtc gggcataagt cagaagctct
    82501 tcaattaaag cttcaagttg actgatatcg cggttcaacg cctgggattc ggcggcgctc
    82561 aggttatcgc tcatctccag tcgataacgc aggcgcacta acggtgttcg cagttcgtga
    82621 gcgataccgt caataagctg ttttttgctg gcaatcaagg cgttgatatt gtccgccatc
    82681 tggttaaatg caacaccaag tcgttcaaag ctcgaaccct catcaaagtg gatacgttca
    82741 ttgagatgcc catcgccaaa tcgttgcgcc gctgcttcca gttttaacat atcctgccag
    82801 tgcggacgca tccagataaa caccggaaag gcgagggaaa tggcaataaa agcgatcagg
    82861 gcgatatcca gcaatcgcat ctgatggagg taataaagat aaggaacagg accaactgcc
    82921 agcacgtagt ggctgcgcgg gatacgttgc aaaaaggtgt actgatcgtc cagagcgaca
    82981 atttcgccgc cacgcagccg gtgcatggaa atatcatcaa gatggtattt actcagcggc
    83041 tcgacacgca gatcgaaaga gagatttaaa tccatctctt tcagcgtctt accccagtcg
    83101 tgtgggggga tctcacgcaa ttcgctgcgc atcagataca gcgaactgtt catcaaatca
    83161 tccagcgact gtttgcctgc gcgttcggcg gtaaatttgt acaccagccc gaccagcaga
    83221 gacatcacaa ggaagcagac aaacaataac aggtaaaact ggataaacag ttttttcatc
    83281 gcttattccc acgcatgagg cgcaaaaaga tagcctttgt tacgcacggt tttaatacga
    83341 taaggttctg cggcgttatc gagcagtttt tttcttaacc gcgaaatagc cacgtccacg
    83401 ctacgatcca gaccgtcata actgacgccg cgtaaatttt tcagcaatgc atcgcggtcc
    83461 atgatttgcc cggcatgggt agctaattcc cacaataatt cgaaatcagc tgtcgagagc
    83521 gagatttcag tgttagccag ggtgactacg cggttgatgg gatcgatggt caacgtgccg
    83581 aaatgcaggg ctttgtaggg agtcagagac gtttcctgaa tacctttggt cactgtagct
    83641 tgctcattct gacgcaaatg caaacgtaaa cgcgctagca aaacagcagg gggcgtcgtt
    83701 ttgagaatat agtcgcaggc gcccatttcc agtgccagga tgtggttcat atcgctatcg
    83761 agagaggtta gaagaacaat cggtccggac cactttgcgc gtaaatcacg acaaatggtc
    83821 atgccgtcct tgcctggtag catgatatcg agtaacacca aatccggatt ttctcgcaga
    83881 atagtttctt cggcccggtc gccgcgcggt tccacggtaa cctgcatatc atgttttgcc
    83941 aggtacgcag caatcagtga accgacttcc gcatcatctt ccacaaatac gatagtgttc
    84001 ataacattca cggtagatat aaaaacgtca caatacaccg cactgttttt acttactatc
    84061 aatcgtttct aaacaaggtt tcatcaggta ttctactgat gacttgttat ggaagtgtta
    84121 aggtaaaaag atggggctgg taatcaaagc cgcgctcggt gcgctggtag tgctgttgat
    84181 tggtgtttta gcaaaaacga aaaattatta tatcgccggg ctgattccac ttttcccgac
    84241 ctttgcgctt atcgcgcatt atattgttgc cagcgaacgc ggcattgaag ccttacgcgc
    84301 aaccatcatt tttagtatgt ggtcgattat tccctatttt gtttacctgg cgtcgctgtg
    84361 gtatttcacc ggaatgatgc gcttgcccgc tgcttttgtt ggctctgttg cgtgctgggg
    84421 aataagcgca tgggtgttga ttatatgctg gataaagctg cattaacgca gatgacgacc
    84481 gccatcaaga gggaaactgc gtccggtgac aaagcagctg gtaagtaagt aatcgaccag
    84541 gtcgatcact tctttctcgc caggcgctgt tttcatcagt gatttattca gcgcctgttg
    84601 tcgatattcg gcatcatcat gttcattaaa caggatcagc gatggcgcaa tagaattcac
    84661 tttcacttcc ggtgccagct tgcgggcaaa cgagcgggtc atattatcca gtgccgcttt
    84721 gcttgcagca tacgcaatat gtttatcgct accgcgctcc accacataat cggtaaagtg
    84781 aatgatatcg ctggcggcgt gtccgtgccc acgcagtaat ctttccagag catggttgag
    84841 caggtatggg gtattaacgt ggatctgcat catgcaagcc agtacgtcgg tcagtagcgc
    84901 acccggtttt tccgccatcc acgcgctggc gttatgcaaa atagcacgca ggccatgggt
    84961 gctttttagt acttcatcgg caaacgccat cacaccgtcg ttggtcgaaa aatcagcctg
    85021 aatacactgc gcacctgcgt taatcagtcc atcaatggct ggatagtgcg tccgatagct
    85081 gataatcacc ggttgctttt gattaatgaa atgccaggcg agggcgaggc cgatgcgacg
    85141 accaccgcca gtaattaata ttggcaaggg ctgggtttta cccatcgtga tctcctttgc
    85201 tatccaacga tgggatgaac gttatcccac cagcatccag gtcgccggaa ctgaggcaat
    85261 taacagcatg ccaatcagca ccatttcctg acgattcagt acattatcat gggtatgcgt
    85321 tttacgcgcg tacaggaaaa ccagcagccc cggtgcatac agaacaacgg ataacagcaa
    85381 gtgcattgga ccagaggcgt acaataacca taagccataa atgcaggcac cgacacctac
    85441 cgctttatgc agtggacggg ttgcgatttt tagcaagaac gcgccgacca ggaaataggg
    85501 caccagaatc atttctgagg cgatggtcag caatgtgttg taatcggaac cggtcagcca
    85561 gatgagcacc agacaaattt gcacgcagat gttggtcagc cacagtgaag cggatggcgc
    85621 agcttgtgcg ttctggcgcg caaaaatgcg cgggaatgct ttatgagtgg cggccaggaa
    85681 cggaacttct gccgccatga tggtccagct taagtacgcg ccgcaaacgg aaacgatcaa
    85741 accggcagcg atgatgattt cgccccacgg tcccatcatt tccaccatca gaccggccat
    85801 tgacgggtta cgaatttcag ccagttcagg acgtgccacc acgcccagcg aaagcagcgt
    85861 taccagcaag taaacgccca gagcggagag aaccgccagc agtgtcgctt tgccaacatc
    85921 acgtttatta cgcgcacgcg cagaaacaac cacggcacct tccacaccaa tgaaaaccca
    85981 cagggtgatc agcatggtgt ttttcacctg ttcccacacg ggtacgccaa gtgcaagtcc
    86041 ggtgaagtcg agcttgaagg tatccagttt gaacatcatc atcgccaaca caacaaacag
    86101 acccagcggc aacagttttg ccagtgttgc caccaggtta atgctggcag cggtttgcac
    86161 cccgcgcagg atcaaaaagt gaacaatcca caataaagcc gatgcaccga cgatcgattg
    86221 ccaggtatta ccatcgccaa acaggcgcaa ttccggcgtg tccgtaaaaa agcttaacgc
    86281 ggaaaaaacg atcaccagat aggagacgtt ggcgatgacc gcgcacagcc agtatcccca
    86341 tgcggaacaa aagccgatta gctcgccaaa cccttcgcgg gcataggtaa agataccgcc
    86401 gtcaagttcg ggacgaatgc gcgtgaggat cagcatggca aaggccagca ataaaatgcc
    86461 agctccagta ataccccagc cgatgagcag tgctgccggg ctggcaactg ccgccatatt
    86521 ttgcggcaga ctgaaaacac ccgcgcccag cattgagctt aataccagcg cggtgagtgc
    86581 gctcagtccc agtttctttt ccatcgatat ccagtgatta aaacgtgata agaagaataa
    86641 atattagggc aaaacgcata aaaatggagt ttgccactga agcgcgggat tttacgaaga
    86701 gatgtgtctg catgcaatgg tcgcggggaa atttgtgact aaaaatgcga aaggcggcat
    86761 caagccgcct tataggagta actgaatagt tatttataca gatctgcgct gacggtcagg
    86821 ttattaccac gttcctgcca ctggcgggtg atgtggtaat acttagcacc tttcttcgcg
    86881 gcacgtttcg caacctgata ggagacttcg gtcatgttgc cgtagttgcc agagaatttg
    86941 atgctgtcga acgggaccat catcgctgcg gtcgctttgt tcagttcttc gactttagtg
    87001 ccatccggga gcgtgacggt gtaacgcccg ccttttgatg actgggtttc aaagaagcga
    87061 ccgacttcag aacttggtga tgcggtagtc gcaacacccg ggatctcaac tttcttcgca
    87121 gcttcgccac cggcagccag agctgcacgt cctgcttcgg aatctgccgg gatcacatcc
    87181 gggctctgga cgatacgttt cttagcatct tttttataga tgaatgcagt aatacgctgg
    87241 ttaccgccct ggttggcatc gatttgacga acaatgtaga aagagtaggc acctttcgct
    87301 tttgctgctt tggtgatggc atcattgact tctggctggc tacgatagaa gccctggacg
    87361 gtgaccgtgt caaacggttc aatcagaaca gcctgatctt tcggcagttc gacaacaccg
    87421 ttaattacgc gattacttgt ttcttctgct ttttcagcat cggctttata gaggtcagcg
    87481 accacacgcc agttaccgct gttaccaaaa tcagaagtgt cgacaacata aaaagaggcg
    87541 gcaccttctt tatctgcgcg acgagaaacg gctttcaccg cttcgccaat agcattaaaa
    87601 cgaccggtaa ccactacacg gtcaaaaggt ttaaccgctg ccgcttgctc cggtgtcagt
    87661 tctgttgctg cgttaacgga gaatgccgta gcagaaagca gtgccgacgc caggagggtg
    87721 ttcttaagct tcataaaaat aatccttcgc cttgcgcaaa ccaggtactg gtattgttat
    87781 taacgagaaa cgtggctgat tattgcattt aaacggtgta actgtctgcg tcatttttca
    87841 tatcacattc cttaagccaa ttttaatcct gctcaaatga ccgtctatgc ttaaaaaaca
    87901 gacgtatcag catcaatact actgaagcaa ctgaattgta taagttaatt taatgttaag
    87961 tagtgattcg taccggggcg atgtctcgtt ttacctgacc gtcgaagaca attatcagtc
    88021 tttatccggc gttctaaggt gtttatccca ctatcacggc tgaatcgtta atattttgcg
    88081 agttcacgcc gaaatactga tttttggcgc tagatcacag gcataatttt cagtacgtta
    88141 tagggcgttt gttactaatt tattttaacg gagtaacatt tagctcgtac atgagcggct
    88201 tgtgtggctc ctgacacagg caaaccatca tcaataaaac cgatggaagg gaatatcatg
    88261 cgaattggca taccaagaga acggttaacc aatgaaaccc gtgttgcagc aacgccaaaa
    88321 acagtggaac agctgctgaa actgggtttt accgtcgcgg tagagagcgg cgcgggtcaa
    88381 ctggcaagtt ttgacgataa agcgtttgtg caagcgggcg ctgaaattgt agaagggaat
    88441 agcgtctggc agtcagagat cattctgaag gtcaatgcgc cattagatga tgaaattgcg
    88501 ttactgaatc ctgggacaac gctggtgagt tttatctggc ctgcgcagaa tccggaatta
    88561 atgcaaaaac ttgcggaacg taacgtgacc gtgatggcga tggactctgt gccgcgtatc
    88621 tcacgcgcac aatcgctgga cgcactaagc tcgatggcga acatcgccgg ttatcgcgcc
    88681 attgttgaag cggcacatga atttgggcgc ttctttaccg ggcaaattac tgcggccggg
    88741 aaagtgccac cggcaaaagt gatggtgatt ggtgcgggtg ttgcaggtct ggccgccatt
    88801 ggcgcagcaa acagtctcgg cgcgattgtg cgtgcattcg acacccgccc ggaagtgaaa
    88861 gaacaagttc aaagtatggg cgcggaattc ctcgagctgg attttaaaga ggaagcgggc
    88921 agcggcgatg gctatgccaa agtgatgtcg gacgcgttca tcaaagcgga aatggaactc
    88981 tttgccgccc aggcaaaaga ggtcgatatc attgtcacca ccgcgcttat tccaggcaaa
    89041 ccagcgccga agctaattac ccgtgaaatg gttgactcca tgaaggcggg cagtgtgatt
    89101 gtcgacctgg cagcccaaaa cggcggcaac tgtgaataca ccgtgccggg tgaaatcttc
    89161 actacggaaa atggtgtcaa agtgattggt tataccgatc ttccgggccg tctgccgacg
    89221 caatcctcac agctttacgg cactaacctc gttaatctgc tgaaactgtt gtgcaaagag
    89281 aaagacggca acatcactgt ggattttgat gatgtggtga ttcgcggcgt gaccgtgatc
    89341 cgtgcgggcg aaattacctg gccggcaccg ccgattcagg tatcagctca gccgcaggcg
    89401 gcacaaaaag cggcaccgga agtgaaaact gaggaaaaat gtgcctgctc accatggcgt
    89461 aaatacgcgt tgatggcgtt ggcaatcatc cttttcggct ggatggcaag cgttgcgcca
    89521 aaagagttcc ttgggcactt cactgtgttc gcgctggcct gcgttgtcgg ttattacgtg
    89581 gtgtggaatg tatcgcacgc gctgcataca ccgttgatgt cggtcaccaa cgcgatttca
    89641 gggattattg ttgtcggagc actgttgcag attggccagg gcggctgggt tagcttcctt
    89701 agttttatcg cggtgcttat agccagcatt aatattttcg gtggcttcac cgtgactcag
    89761 cgcatgctga aaatgttccg caaaaattaa ggggtaacat atgtctggag gattagttac
    89821 agctgcatac attgttgccg cgatcctgtt tatcttcagt ctggccggtc tttcgaaaca
    89881 tgaaacgtct cgccagggta acaacttcgg tatcgccggg atggcgattg cgttaatcgc
    89941 aaccattttt ggaccggata cgggtaatgt tggctggatc ttgctggcta tggtcattgg
    90001 tggggcaatt ggtatccggc tggcgaaaaa agttgaaatg accgaaatgc cagaactggt
    90061 ggcgatcctg catagcttcg tgggtctggc ggcagtgctg gttggcttta acagctatct
    90121 gcatcatgac gcgggaatgg caccgattct ggtcaatatt cacctgacgg aagtgttcct
    90181 cggtatcttc atcggggcgg taacgttcac gggttcggtg gtggcgttcg gcaaactgtg
    90241 tggcaagatt tcgtctaaac cgttgatgct gccaaaccgt cacaaaatga acctggcggc
    90301 tctggtcgtt tccttcctgc tgctgattgt atttgttcgc acggacagcg tcggcctgca
    90361 agtgctggca ttgctgataa tgaccgccat tgcgctggta tttggctggc atttggtcgc
    90421 ctctattggt ggtgcagata tgccagtggt ggtatcaatg ctgaactcgt actccggctg
    90481 ggcggctgcg gctgcgggct ttatgctcag caacgacctg ctgattgtga ccggtgcgct
    90541 ggtcggttct tcgggggcta tcctttctta cattatgtgt aaggcgatga accgttcttt
    90601 tatcagcgtt attgcgggtg gtttcggcac cgacggctct tctactggcg atgatcagga
    90661 agtgggcgag caccgcgaaa tcaccgcaga agagacagcg gaactgctga aaaactccca
    90721 ttcagtgatc attactccgg ggtacggcat ggcagtcgcg caggcgcaat atcctgtcgc
    90781 tgaaattacc gagaaactgc gcgctcgtgg tatcaacgtg cgtttcggta tccacccggt
    90841 tgcggggcgt ttgcctggac atatgaacgt attgctggct gaagcaaaag taccgtatga
    90901 catcgtgctg gaaatggacg agatcaacga tgactttgct gataccgata ccgtactggt
    90961 gattggtgct aacgatacgg ttaacccggc ggcgcaggat gatccgaaga gtccgattgc
    91021 tggtatgcct gtgctggaag tgtggaaagc gcagaacgtg attgtcttta aacgttcgat
    91081 gaacactggc tatgctggtg tgcaaaaccc gctgttcttc aaggaaaaca cccacatgct
    91141 gtttggtgac gccaaagcca gcgtggatgc aatcctgaaa gctctgtaac cctgacggcc
    91201 tctgcggagg ccgtcactct ttattgagat cgcttaacag aacggcgatg ctttgacctc
    91261 ccgctgtttg ttcaagtgca attttgacaa taattgttaa cggcacggaa agcagcatac
    91321 ccaccggtcc taacaaccat ccccaaaaaa tcaacgacaa aaataccacc aatgtggaaa
    91381 gccccagccc acgacccatg atgcgcggct ccagaatatt gccgaagacc agattaatta
    91441 gcagatatcc cgccagcacc agcaacgctt cgtagaagcc attaaacacc agtacctgag
    91501 cgataggggg gattgccgcg agaactgaac caatattagg gatgtaatta agcgcaaagg
    91561 ccagcaatcc ccagacaaaa gcgaagcgaa catcgagtgc ggcgagcatc gcccaagcga
    91621 ccaggccggt gatgatgctg atggctgttt tcagcaccag ataatgagac acactgtcaa
    91681 tcgcacgctg aatcgccgcc atcccttcaa ccggacgcac catcatttgc tgaaattttc
    91741 cgggcaattg tggcacttcg agcaacataa acagcaccgt cagcagcaat aaaaagattg
    91801 atgacatggc attagataac tgcgtcaata agttggtgag caacgtcatt gccgcgttcg
    91861 gatcaatgta atgcgccagt tggtcaactg agacatcaat ccctacgcgt tgcaacaacg
    91921 gttcaatcgc ttgcagcggc gtcataatag agttgcgata ttgcggtaac gtccgcgtca
    91981 actcgttgag cgcggaaccc agataagcta acagcaacac catcgccatc acgatgatgg
    92041 tcatcaaaat cgacaccgcc agtacacgcg gcactcgcca gcggaccatg tgttgcacca
    92101 gcgggttaag aataacagca ataaataatg cgagaataaa cggcacgatg atctcggcgg
    92161 caaaacggat accgcagaga ataatgacca gcattcccaa cataatgacg atttttaggc
    92221 cattgagcgt gatgatcggc tttgccatgc ttgtccccgt tttttcttcc tttgctaata
    92281 ataatgtctt tttcgctccg tcatcataac gaaaatcaaa ccgctcaggt aaagaagtga
    92341 aaatattttg agttaattct taagctatga tacaaatcag gcgtgttcaa ctaccgagga
    92401 caattatcat ccgcgatgac gagaagcaac actgcggata attgtaatat tatggacaat
    92461 ttgttcagga cgttattttc tacatttacc catcttcgta cctcatccac tatcttgctc
    92521 gtaggtgagc agcactggcg caacgcgctt tagtcctttc tcctgcttaa gcttgcgcta
    92581 tgcgcggggc ttgaccactt tactttggtt tcgctgaatt aagcgaaaat taaaataatt
    92641 ctcttgcagg agaaggacaa tgtatattta ttggatttta ttaggtctgg ctattgctac
    92701 agaaattacc ggtacgctgt ctatgaaatg ggcgagcgtc agtgagggaa atggcggctt
    92761 tattttaatg ctggtgatga tttctctgtc gtatatattt ctctctttcg ccgttaaaaa
    92821 gatcgcctta ggcgtggctt atgcgctgtg ggaaggtatc ggtattttat ttattacctt
    92881 gtttagcgtt ttgttattcg acgaaagttt atcgctgatg aaaattgccg ggttaaccac
    92941 cctggtcgcc gggattgtgt tgatcaaatc aggtactcgt aaagcgcgta aacctgaact
    93001 ggaggtgaac catggcgcag tttgaatggg ttcacgccgc ctggctggca ttggcaatcg
    93061 tgctggaaat cgttgctaac gtctttttga aattttctga cggctttcgt cgcaaaatat
    93121 ttggcttgct ctccctggcg gcggtgctgg ctgcctttag tgcgctttct caggccgtta
    93181 aagggatcga cttgtctgtc gcttatgcat tgtggggcgg gtttggtatt gccgccacgt
    93241 tagccgcagg ttggatcttg tttggtcaac ggttaaatcg taaaggctgg attggcctgg
    93301 tcttgctgtt ggctggaatg atcatggtga aacttgcctg atgaacacgc tgcccgcact
    93361 gtcgggcagc gtttgaacat tatttttgcg acagttgatc cagcttgtcg cgaaaaccgg
    93421 taacagaaat ggcccggtta tcggcgcgcc agcgatcttt cgcggcagga gccgaacttt
    93481 gcaccccaat taattgccag ccgtcatcgg tatgcaacat cagaggcgaa ccgctgtctc
    93541 ccggcaaggt atcgcactga tgcgacatca ccgacgtttg cgcccagcca gtcacttcac
    93601 agttttgatg actgtacaac gtatcgagat gatcttcagg gtatcctgcc tgagtcactt
    93661 tacgacctgc cgcttttaat gcggcggtaa gtgcggcttt atctccctca aataacggca
    93721 atggtgtaat gccagaaggg ggattacgta gcacaatcaa accgaagtcc cacggcgcag
    93781 ctgcgggagg tacaatccag ccatccccat ctgcttttaa ccgctttccc agtgtcggat
    93841 caacgcggcc ttctatgtcg tggatctcat agcgccaaag acctttattt gacacgaaac
    93901 gcagcgctac cgctttatcg gctttaccct ttggcggcgt caataaacag tgtcctgccg
    93961 ttaatgccag attgggtgca atcagcgtcg ccgtacataa attgccgctg gccgtttcca
    94021 gttgcccaac agcatcccac ggtgattggg tcgtgtcatt cactggcaca cgatcatcat
    94081 gaccaaaaaa cagggtgctg acctcatcgt ttgccgattt ggcaacgtct ggtttatctg
    94141 caaacacaaa agcagacgtc aaactaattg cacccaacac tacagcaatg gttgtacgca
    94201 tatcacactc tggtgggtaa ttatgattat taaaagcaaa ccctcataaa tactatagac
    94261 gggacgggat gaaagtggga gtaaaatcag ataactacga tcaggaaaga taaaaacggg
    94321 cggcaatcag tgcgcataaa ataaggatga taagaatgaa ctcaaagcga taacggccca
    94381 ccatactacc ctccgctaaa ggcggtgcta aacgttaccc gcttagcacc gtaattttca
    94441 ggcgcgaggg ggcgcgccag cattactgtt gaaaacttac gctgcgggtt gtgcagcagg
    94501 ttttgccggt tgctgatggc tgtgtttttt ggcgtgtttc ttcgctgcct gcgctttttg
    94561 ttcaggagct ttctgttcag ctttcgcatt tttatgatgc tttttagccg cctgcgcttt
    94621 ctgggcaggt gctgctttat gctgtttttt atgatgtgta gttttcgccg gcgctgcttt
    94681 ggtggtcgtc gcagtcggag caggtgtggt cgcagtttct gcagcaaagg cggcagaaga
    94741 cagacccata gcagcggcaa caaccagagc taatactttt ttcattgtca taccctcaat
    94801 ttgttttttc atttaacccc actgcggggc cgttgaaata actatatccc tgggaatggc
    94861 agacttccgt gagtggttgg tttcagcgtg taacgatatg tacaaacgct gaataaatta
    94921 cagcgttgat aataacgtat tgtgacttaa gggaaattta gctaccaata atagtagtct
    94981 tgatcgggtt aactatttta ctacttacaa agcggtagaa taactgcgca tcagtaataa
    95041 atgacacaca gcaaaatgaa tccgtttatt tgggtactta taatcctgat gacgctagat
    95101 gcgctgcggg aattggctgg cgcttcgtct attttagaat ggctattaac gttggtttga
    95161 gcaggcaata agtccggatg ggtatttacc gcagtccgga cttatttttc aggcgtgcag
    95221 acgacgatgc aaacgcgtcc cgaccagcag agcaatgacc agcatcagag caataaatgc
    95281 gccgacgccg ttccagccat agttatgcca gaaaacacca cccagcgtcc cggcaatact
    95341 cgaccccaga tagtaactga acagatacag cgaggaggcc tggcctttag cgcgttttgc
    95401 gcgggggccg atccagctgc tggctactga gtgggctgcg aagaatccgg ctgagaagag
    95461 taacattccg gcaaagatca gccacagcga gctaaataag gtcatcagta aaccaaacag
    95521 cataaccccc gtcgaaaaca acatcaccgg accgcgccca tagcgggtgg tcatggttcc
    95581 ggctttgggt gagctccatg taccggtcaa ataggccagc gataataagc caaccacagc
    95641 ctgactgaca tgccaggggg agagcatcaa ccgatagccg atgtaattaa acagcgtgac
    95701 gaacgacccc atcagcaaaa agccttctgc gaacaataac ggtaatcccc ggtcacgcca
    95761 gtgcagacga aagttgataa acaacgtctt aggtcgcagc gaagtcgggc gaaaatggcg
    95821 tgattccggg aggattttcc agaacatcaa cgccgaggcc agcgcgaaac aaccgattgc
    95881 cgccagcgca attcgccagt tgaaaaagtc cgtgaagaca ccgctaatta agcgtccgct
    95941 catgccgcca attgagttgc cgctgatata caaccccatc gaaaaggcca cgaaactggg
    96001 gtggatttcc tcgctaagat aagtcatgcc aacggctgcc acgccactta acgaaagccc
    96061 aatcaaggcg cgcataatca aaatgccgtg ccagctggtc atcattgtcg aaagtaacgt
    96121 acaaatggag gccaacagta gcgccgtgac catcactggt ttgcgaccaa tggcatcgga
    96181 tagcgggcca gtaaacagca aaccgatagc caacatcgcc gttgaaatgg acagtgaaat
    96241 actactgttc gcgggcgtta agccaaactc ctgcgaaagc accggaagga taggttgcac
    96301 acaatagaga agtgcgaagg ttgccagtcc ggcagagaac agcgccaggg tgacgcgcat
    96361 aaattgcggc gtaccgcgtt taataaattg atttggctga gaaatgcttt gcttgtcagt
    96421 gtcgcttgcc ggagcgccat caacagttgt agtacggctc acttgaaatc cttgctaaat
    96481 atgcctgtgg atcaggctta tgaatagatt aggaaaatgg aattgttctg tctaatatat
    96541 taataatctc aaataagatg ttttaaatat gaatattgaa cttcgtcatc tgcgttactt
    96601 tgttgctgtt gcagaagagc tgcatttcgg gcgcgccgct gcccgcctga atatttcgca
    96661 accgccgcta agccagcaga ttcaggcgct ggaacaacaa attggtgccc gactgctggc
    96721 acgaaccaat cgcagtgtat tgctgacggc agcaggaaaa cagtttcttg cagatagtcg
    96781 gcaaatcctg tctatggtgg atgacgctgc cgctcgcgct gaaagactgc atcagggtga
    96841 agcgggggag ttgcgtattg gttttacttc gtccgctcct tttattcggg cggtgtccga
    96901 tacgttatcg ctgtttcgcc gtgattatcc tgatgtccat ttacaaaccc gcgaaatgaa
    96961 cactcgcgag caaatcgctc cgctcattga aggaacgctg gatatgggat tgctgcgtaa
    97021 cacagcgtta ccggagacgc ttgaacacgc agtcatcgtc catgaaccgc ttatggcgat
    97081 gatcccgcac gatcatcccc tggcaaataa cccgaatgta acgctggctg aactggcgaa
    97141 agaacccttt gtcttttttg atccgcacgt cgggacaggg ctgtatgacg atattctcgg
    97201 actgatgcga cgttaccatt tgacgcccgt catcactcag gaggtgggcg aggcaatgac
    97261 catcatcggt ctggtttccg ccggtctggg tgtctcaatt ttgcctgcgt catttaaacg
    97321 agttcagctc aacgaaatgc gctgggtgcc gattgctgaa gaggatgcgg tttctgaaat
    97381 gtggttggtc tggccgaaac atcatgaaca aagtccagct gcgcgaaact ttcgtattca
    97441 tctgctgaat gctctcaggt gagggaaatt tcagcgaaaa agcccgaaaa atgtgctgtt
    97501 aatcacatgc ctaagtaaaa atttgacgac acgtattgaa gtgcttcacc atagcctaca
    97561 gattatttcg gagcgcgaaa atatagggag tatgcggtgg ttgctgaaaa tcagcctggg
    97621 cacattgatc aaataaagca gaccaacgcg ggcgcggttt atcgcctgat tgatcagctt
    97681 ggtccagtct cgcgtatcga tctttcccgt ctggcgcaac tggctcctgc cagtatcact
    97741 aaaattgtcc gtgagatgct cgaagcacac ctggtgcaag agctggaaat caaagaagcg
    97801 gggaaccgtg gccgtccggc ggtggggctg gtggttgaaa ctgaagcctg gcactatctt
    97861 tctctgcgca ttagtcgcgg ggagattttc cttgctctgc gcgatctgag cagcaaactg
    97921 gtggtggagg aggcgcagga actggcgtta aaagatgact caccattgct ggatcgtatc
    97981 atttcccata tcgatcagtt ttttatccgc caccagaaaa aacttgagcg tctaacttcg
    98041 attgccataa ccttgccggg aattattgat acggaaaatg gcattgtaca tcgcatgccg
    98101 ttctacgagg atgtaaaaga gatgccgctc ggcgaggcgc tggagcagca taccggcgta
    98161 ccggtttata tccagcatga tatcagcgca tggacgatgg cagaggcctt gtttggtgcc
    98221 tcacgcgggg cgcgcgatgt gattcaggtg gttatcgatc acaacgtggg ggcgggcgtc
    98281 attaccgatg gtcatctgct acacgccggc agcagtagcc tcgtggaaat aggtcacacg
    98341 caggtcgacc cgtatgggaa acgctgttat tgcgggaatc acggctgcct cgaaaccatc
    98401 gccagtgtgg acagtattct tgagctggca cagctgcgtc tcaatcaatc catgagctcg
    98461 atgttacatg gacagccgtt aaccgtggac tcattgtgtc aggcggcatt gcgcggcgat
    98521 ctactggcaa aagacatcat taccggggtg ggcgcgcatg tcgggcgcat tcttgccatc
    98581 atggtgaatt tatttaaccc acaaaaaata ctgattggct caccgttaag taaagcggca
    98641 gatatcctct tcccggtcat ctcagatagc atccgtcagc aggcccttcc tgcgtatagt
    98701 cagcacatta gcgttgagag tactcaattt tctaaccagg gtacgatggc aggggctgcg
    98761 ctagtaaaag acgcgatgta taacggttct ttgttgattc gtctgttgca gggttaacat
    98821 tttttaactg ttctaccaaa atttgcgcta tctcaatttg ggccaggaaa gcataactta
    98881 gactttcaag gttaattatt ttcctggttt atatttgtga agcataacgg tggagttagt
    98941 gatgctgaag cgtttcttta ttaccggtac agacacttct gtagggaaaa cggtggtttc
    99001 ccgcgcattg ctacaagcgt tagcctccca gggaaaaacg gttgcgggat ataaacccgt
    99061 agcgaagggg agcaaagaga cacccgaagg gctgcgtaat aaagatgccc tggtgttgca
    99121 gagtgtttca accatcgaac tgccttatga agcagttaat cctatcgcgt taagcgaaga
    99181 agaaagtagc gtggcgcaca gttgcccaat caattacacc ctcatttcaa acggcctggc
    99241 aaacctgacc gataaagtcg atcatgtggt ggtagaaggg actggcggct ggcgcagtct
    99301 gatgaatgat ttgcgtccgc tctctgaatg ggtggtgcag gaacaactgc cggtgttgat
    99361 ggttgtcggt attcaggaag gttgcattaa ccatgcactg ctaacagctc aggcgatcgc
    99421 caacgacggg ctaccgctca ttggctgggt ggctaaccga atcaatccag gactggcgca
    99481 ttatgcggaa atcattgatg tgctcggtaa aaaacttccg gcaccgctca ttggtgaact
    99541 gccttatctg ccgcgcgccg aacagcgtga actggggcaa tacatccgct tagctatgct
    99601 tcgcagtgtg ctggcggtag atagagtcac ggtgtaacgt ccgcgaaatt accgacgcaa
    99661 ttacgcaggc aatcaataaa ccggggagta gctgatactc cccggtcatt tcacatatca
    99721 tcaacgtcga cataatcggc gcgtgcgtgg ttgccgccaa cagtgtcgcc atcccggtca
    99781 atccgagtaa aagcgtaatt tcttcgccat cagggaacca taatcccagg ctacgaccat
    99841 acaacatgcc aatggcaaga ccgataaata gcgtcggtgt aaagacacca ccgggcgcgc
    99901 cagaaccact actcgccagc acggcaaaca gtttacagag gaagatcccg gcaatgatca
    99961 ttaacagtgg cggggcggtt aaaaaggatt gtacggtgct atagccgttg ccccacactg
   100021 caggtgtgaa cagggaaagc agacccacga tcaacccgcc cagtgccagt tgccagggcg
   100081 gcgcaagttt gagacttaca aatccacgat gacaggcgtt cattaacgtt aacaacagtg
   100141 gtccgcacag acctgccagc acacctgtac tgataatcag cgcatagtca cgagcctgaa
   100201 ccgtcactga gagttgtacg ctgtagagta acgcgtcgct atgattaatc agattgctaa
   100261 ccagcaacgc cacgacggcg gaaataatca ccgggccgag agaggccaac atcatagtgc
   100321 caaacagcac ttcggctata aataaactgc cagcaagcgg ggcgcgatag gccgcagcca
   100381 ttcccgccgc agctccacag gcgatccata atttccactc ctggcgtggc gtaaaacgtt
   100441 gggcaaaaca ggaggcggca agggcagcta aaagaatcat cgcaccttcg cgaccaattg
   100501 cactgccgct ggttactacc agcagagagg caagcgattt aaccaggctt gctgcgtaat
   100561 cgaactgacc atcggtttgc aacgcttcca tgtaatcggt cggcgcatga gggcgttgct
   100621 gggtaaattt ctgccagccc atcagcaaca aacccgccgc cagtccgccg agcgccggag
   100681 ttagcagccg tcgccatggg gaaagatttg tcgctgcatt gaccagactg ccggagtcat
   100741 tattgaggaa caaccactcc agtagcagca ttgcatgacg aaacccggca acggcaaagg
   100801 ccgcgagaat accgacgact gttgcgataa gcagacggcg gaacatagtg cgcagatccg
   100861 gatagatgtg tagatgatgc atgagcagaa atgggcaatg aaacacgggc gactattttg
   100921 cggcaaaaga ggccagccgc aaaagcagtg cgtgctttaa gagataaaaa aacgtgacac
   100981 tgtaacgtat tattgccgaa tcgcgcgtaa tcgtcaccat ccggcaatat tacggtgatc
   101041 ctatcgaaac agcggtttaa ccgcgacagg aatcaacagt tgtgattgcc attgcgccag
   101101 cgttaagcga gcgagttcac ccagtgcacg gtagaaaggg tgttctgctt tttcgataaa
   101161 aacgtcaaga aaacgtgttg accacggaaa aaggtgccat gccagcaatt cttcgcattc
   101221 tgtctggcga ccattctccg ccaaccacgc agccatcaac agcagtgaac caaaatgatc
   101281 ttccggttcg ttttgctgca tttcaaactg aatgcctttc tcgcgcatcc actgacgaag
   101341 tgccaatgtt gaatcgccaa acagcacaga ttcgcgatcc agccagaccg atccccacgg
   101401 cggtgacggc agtgcccacg ggccgacaaa caaacgctgc caggcctggg cgtgagtctc
   101461 ttcactctgt gtctgaaaag cagtcaccag cggcgctaat gacgcttctg gtagaggcca
   101521 ctgagtttcc cagctgtcat tggtgagtac cgcaaccaga ggtgcggctt ccgcactctc
   101581 tggagcgtaa taaaacagcg cgcccaacac gcgcgccgcg acagaaaaat tatcttgctg
   101641 tgaaaaatgg gtcattccta acatcctgaa atgtgcgggt tgccccgcac caatttgtta
   101701 acctgcaata gccattccta ccgtcatgtg caggccataa aagagcacac gcccgatcat
   101761 ctcaccgcca agtatgagga ttagccccag aacaagtccg gcaacgtgag gttcacggcg
   101821 acgaatgagc ggacaaagcc agcatcctag acctgcgcat aacaatacca cacgccagac
   101881 ctgtaaggag gcgtaatctg gtaccagtgc gctggcttgt tgtacggatg agtgaataga
   101941 cgccagagac aaaccttgca gcacaatcac cccggcacaa gcgatcagcg ccagaacgct
   102001 aatgatggca aatggtgtgg tattaaatgt aacgcgggct gctcgcagaa ttgcggcagc
   102061 aagtattgga ccgctcaaca atactgtcag gaagaaagcc agcgtagtgt aaccgttatg
   102121 ccaggttggc actgtgtcga tttgatacac gcaggtcatc atccagacga aaatgacgcc
   102181 gagcgccatg ctgacaagta accagagttt ccccaacgct tgcggcattt taccgatgac
   102241 tgccaccagc caccataatc cgccaacggc aaaaaatatg gaaccggcag caatctcgtt
   102301 actcagacca gaatctccga ttcgattcag cgagttaaac gcccgcagtg gcgaccccag
   102361 gtgcatgaca gaggcaataa acccgatgcc catcaacagc cagaggaaaa acatgccacg
   102421 gacaatacgc tgacggtctg cgtcattttt ggcggcgaac cagccaattc cgctaacaat
   102481 cagcgcgcct actacgcatt gacccaatac ggtaaagata accagtggcc attcatgcca
   102541 tccatttccc attttacact tcctccggat tagccagata accagtggta tcgccggtcg
   102601 ggcggctgtt ggcgttaggt ttgataacga tattgggttt tgtgaaatgc gcgcgcggca
   102661 gtggcgcaac ggcagccaga gtgccgtgct tctggcgcag ctcttcaatt ggaccgaatt
   102721 caagtgcacg cagcgggcag gattcgacac atatgggttg tttcccctcg gcgacgcgcg
   102781 aataacaacc atcgcacttc gtcatgtgcc ctttttcagc attgtactgt ggtgcgccgt
   102841 acggacaagc catgtggcag tagcggcagc cgatacaaac atcttcatca accaccacaa
   102901 agccatcttc acgcttatgc attgcgccgc tggggcagac ttttgtacat gcggggtcat
   102961 cgcaatggtt acaggagatg gagagataat aagcgaacac gttctggtgc cagacgccat
   103021 tatcttcctg ccagtcgccg ccagcatatt cataaatacg gcggaaactg acttccgggc
   103081 caagatcttt aaaatctttg cacgccagtt cgcaggtttt acagccagta cagcggctgg
   103141 aatcgataaa aaatccatat tgtgtggtca tgggctactc cttaaacctt ttcgatctgg
   103201 acgagattgc tgtgcgacgg gtttcccttt gccagcggtg aagggcggtg agaggtcaga
   103261 atattgatac tgccgccgtg atcgacccgg tcaccaaaca tatccgcttt aagccacgca
   103321 ccttgcccga tggcggtaac gccaggcaga atacgcggag tcacttttgc ggcaatcagc
   103381 atttctccat tagtgttaaa tacccgcacg gtatcgccat gacggatacc gcgtgcctga
   103441 gcatcaatag ggttgatcca cacctcttgt gggcaggcct gctgtaacac atcaatattg
   103501 ccgtagctgg agtgggtacg cgctttgtag tggaagcccg ttaactgcag tggataggtt
   103561 ttccgcaggg gatcgtccca gccatcaaaa cctggggtat atgcaggaag gggatgaata
   103621 atttcatctt ttttcaattc ccaggtatcc gcaatcgtcg ccagtcgttc agaataaatt
   103681 tcgattttcc ccgaaggtgt tttcaacggg tttgcctgtg gatcttcacg gaatgcgcgg
   103741 aaagcgacgt agtgttcttc cgggcatttt ttcttaaaga tcccggtcgt tttcatctcc
   103801 tcgtagtcgg gcatctcagg gttacgttcc ttcgttttcg catggagata tttgatccat
   103861 tcatgctgac tgcgaccttc agtaaaggtt tgataaacgt ctggtcctaa gcgtttggcg
   103921 acttcactca gaatccagta gatgggtttg cgttcaaatt ttgctgaggt tgcgggttgg
   103981 gcgaggatca catatcccat attccctgca gattcatgag agataaggtc ttcttgctct
   104041 gttggcatca ggtcgggcaa caggatatcg caatacttag ccgaggcagt catgaagtgg
   104101 tcaatgccaa caatcatctc gcacttgctg tcatcctgaa gcacctcatg ggtgtgattg
   104161 atgtcgccat gttgattgat caatgtgtta ctggcgtagc accataaaaa cttgatgggg
   104221 acatccagtt tttcttttcc acgaacacca tcacgggtcg cggtcatttc cgtaccatgg
   104281 tcgatggcat ctgtccatgt aaagacggaa atctgcgttt taacaggatt ctcgagcatc
   104341 gggaaccatt ctactcccag atcccagcta ccttcgcgta cacctgagtt gccgccgttt
   104401 atgccgacgt taccggtgag aacggaaagc atggcaatag cgcgggatgt ttgctcgccg
   104461 ttggaatgtc gttgtggccc ccaaccctga caaatataag ccggttttgc tgaaccgatc
   104521 tctcgtgcca actggataat tttttctgcc gggatgctgg tgatttttgc tgcccattcc
   104581 ggcgttttag ctatgccgtc aggcccttcg cccagaatat aggctttata atgcgcgtta
   104641 cgaggtgcgt tggcgggcag cgttttttca tcgtaaccaa cacaatattt gtcgagaaat
   104701 ggctgatcga ccatgttttc agtaatcagt acccaggcaa tcgcacaggc cagtgcgcca
   104761 tcggtgccag ggcgaatggg cagccattca tcttcacgcc cggcagcagt gtcgttataa
   104821 cgtggatcga tgacgatcat gcgtgcattt gaacgttcgc gggcttgctc gacgtagtaa
   104881 gtgacaccac cgccgctcat ccgggtttct gccgggttat ttccgaacat aacgaccagt
   104941 ttcgtattgg cgatatcatc cgggctgttg ccatcattgg caccgaacat ataactcatc
   105001 gcggcactga tctgtgcggt actgtagcta ccatagcgac tgagaaaacc accgcatgag
   105061 ttcatcagac ggtacgggac gttcgagttg gtgatgtttc cgccatctac gcctgttccg
   105121 tacaggacat gtacagcctc attgccgtaa tctttaagga tccgccgaag attatcactg
   105181 atggtatcca gggcttcatc ccaacttatc cgttcaaatt taccttcacc gcgcttgccg
   105241 acgcgcttca tgggatattt caacctgtca ggatgattca tccgtcggcg gatagagcgc
   105301 ccgcgtaaac atgcccgaac ctgatgatta ccgtaaacgt cgtctcctgt cgtatcagac
   105361 tccacccagt acacggtgtc atctttcaca tgcaaacgta acagacagcg gctcccgcag
   105421 ttaacggtgc aggaactcca gaccgctttc tcttctaccg gtgtctctgc cgctcggacc
   105481 atttgggaaa atggcagagt gaaagcactg cttgccagcg caagactgcc aagtgcggag
   105541 gttttcatca gacttctacg gctgatttca gccttcatga gcgcctctgt ggtatggatt
   105601 ttcatcatta ctcacttatt gcttttcaaa caaaatgtca tgccagaatt tatggttgta
   105661 gagggttata ttttttcgat ctcgaccaga ttagtgtgct gcgggtttcc cttcgccagt
   105721 ggtgaggggc gcagagtggt tagcgtattc acacagccgc catggtcgat tttatcgcca
   105781 gacatattgg cctcgtgcca ggctccctgg cccatagcgc taaccccagg gagaatgcgt
   105841 ggtgtcactt tggctggtag ccgaacttcg ccacgatggt taaacacccg caccatatcg
   105901 ccgttggcaa tcccacgttt ctgtgcatct atagggttga tccacacttc ctgacggcag
   105961 gctgccttca ggacatcaat attgccgtag gtcgagtgag tacgggattt gtaatggaaa
   106021 ccaaacagtt gcagtggaaa ggtactacgt tcaggggagt cccagccttc aaaggttgag
   106081 gcataaaccg gcagtgggct tatcacttca tctttttcca gttcccaggt acgggcaatt
   106141 tccgccagct tgctggagta aatttcgatc ttaccggaag gcgttttaag tggatttgcc
   106201 tcggggtcgt cacgaaatgc tttgtaggcg acaaaatgac cattgggatc tttacgctta
   106261 tagataccca tttttttcag ttcgtcgtaa gacggtaacg ccggatcttt ggcaagcatt
   106321 ttggcgtaca gatgttgtaa ccattgttcc tgagtgcgac cttcagtgaa cttttgatag
   106381 acgtcaggtc caagacgttt cgcgacctca ctcaggatcc agtaaatcgg tttgcgttcg
   106441 aatttttcgc tggtgactgg ctgaaggaaa atgagatatc ccatgttacc ggcgtaatcg
   106501 ttaggaataa tatcttcctg ctcaacggtc atcaggtctg gcagcagaat gtcggcatat
   106561 tttgccgatg aggtcataaa gttttcgatg accacaatca tttcgcattt cgattcgtcc
   106621 tgcagaattt catgcgtttt gttgatgtca gaatgctgat taaccagggt atttcccgcg
   106681 tagttccaga tgaacttaat gggcacatcc agtttatctt tgccccggac gccgtcgcgg
   106741 attgccgtca tttgcgggcc atgatcgata gcatccgtcc agctgaagca ggagattgac
   106801 gttttgaccg gattatccag caccggcagg cgttctatgg taatggtata ggtcgattca
   106861 cgcgcgccac tatttccgcc gctgatgccg acattgcccg tcaaaatagg caacatagca
   106921 atagcgcgtg cggtcagctc accgtttgcc tggcgttgcg gcccccagcc ctggcagata
   106981 taagcgggtt ttgctgtgcc aatttcacgc gccagcttga tgatacggtc caccgggata
   107041 ccggtaattt gcgaagccca ctgcggcgtt ttcgctgttt tatcatcacc ttcaccaaga
   107101 atataggctt tatagtgacc atttattggt gcatctgcgg gtaaggtttt ttcgtcatag
   107161 ccgacgcagt atttatcgag aaaaggttga tcaacgagat tttcgttaat caatacccag
   107221 gcaatacccg caaccagcgc ggcatcggtg cccgggcgaa taggtagcca ttcgtcttca
   107281 cgaccagcag ccgtatcggt atatcgcgga tcgataacaa tcatttttgc gttcgatttc
   107341 tcgcgcgctt tttcaagaag ataagtgatg ccaccgccgc tcatgcgggt ttctgccggg
   107401 ttgttaccaa acatcacgac cagcttgctg ttttcaatat ccgtggtgct gttgccatca
   107461 ttactgccgt aggtgtaggg catggcacag gaaatttgcg cggtgctgta ggagccatac
   107521 tgattgagtg aaccgccgta gcagttcatc aggcgtttga ccgccgaggc tgatggtgaa
   107581 gagcgggtca tattgccgcc aacgatccct gaagagtact gaatatatac agcctcattg
   107641 ccatattgtt cgacggtttt tttcaggcta ctggcgatag tatccagggc ttcatcccag
   107701 ctaatccgtt cgaatttgcc ttcgccgcgt ttgcccacgc gtttcattgg gtaattcaag
   107761 cgatcgggat gattaatacg ccgacggatg gagcgaccgc gcaaacaggc acgtacttga
   107821 tgattgccat actcgtcgtt gccggtgttg tcagtttcca cccaggtcac ttcattatct
   107881 ttaacatgca gacgaagtgc acagcggcta ccacagttga cggaacaggc accccagacc
   107941 actttctcgc tggcctgttg taccgctgcc gctgcactgc gcagggtgaa cggtaaagaa
   108001 aaaccacctg cagccagcgc cagagaacct atcgcggtag atttaacgag tgttctgcgg
   108061 ctgatgccca ccatttgttc atttttggac ataactcact ccctgttctt tatcgttata
   108121 taaaagttt
//
LOCUS       DADXDL010000006        96395 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.006, whole genome shotgun sequence.
ACCESSION   DADXDL010000006 DADXDL010000000
VERSION     DADXDL010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 96395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 96395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..96395
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.006"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1181
                     /gene="proV"
                     /locus_tag="IRB70_000539"
     CDS             <1..1181
                     /gene="proV"
                     /locus_tag="IRB70_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein ProV"
                     /protein_id="HBC0630493.1"
                     /translation="NLYKIFGEHPQRAFKYIEQGLSKEQILEKTGLSLGVKDASLAIE
                     EGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKKIAM
                     VFQSFALMPHMTVLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGG
                     MRQRVGLARALAINPDILLMDEAFSALDPLIRTEMQDELVKLQAKHQRTIVFISHDLD
                     EAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRGVDISQVFSAKDIARRTP
                     NGLIRKTPGFGPRSALKLLQDEDREYGYVIERGNKFVGAVSIDSLKTALTQQQGLDAA
                     LIDAPLAVDAQTPLSELLSHVGQAPCAVPVVDEDQQYVGIISKGMLLRALDREGVNNG
                     "
     gene            1174..2238
                     /gene="proW"
                     /locus_tag="IRB70_000540"
     CDS             1174..2238
                     /gene="proW"
                     /locus_tag="IRB70_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     permease ProW"
                     /protein_id="HBC0630494.1"
                     /translation="MADQNNPWDTTPAADSAAQSADAWGTPAAAPTDGGGADWLTSTP
                     APNVEHFNILDPFHKTLIPLDSWVTEGIDWVVTHFRPVFQGVRVPVDYILNGFQQLLL
                     GMPAPVAIIVFALIAWQISGVGMGVATLVSLIAIGAIGAWSQAMVTLALVLTALLFCI
                     VIGLPLGIWLARSPRAAKIIRPLLDAMQTTPAFVYLVPIVMLFGIGNVPGVVVTIIFA
                     LPPIIRLTILGINQVPADLIEASRSFGASPRQMLFKVQLPLAMPTIMAGVNQTLMLAL
                     SMVVIASMIAVGGLGQMVLRGIGRLDMGLATVGGVGIVILAIILDRLTQAVGRDSRSR
                     GNRRWYTTGPVGLLTRPFIK"
     gene            2295..3287
                     /gene="proX"
                     /locus_tag="IRB70_000541"
     CDS             2295..3287
                     /gene="proX"
                     /locus_tag="IRB70_000541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     substrate-binding protein ProX"
                     /protein_id="HBC0630495.1"
                     /translation="MRHSVLFATAFATLISTQTFAADLPGKGITVNPVQSTITEETFQ
                     TLLVSRALEKLGYTVNKPSEVDYNVGYTSLASGDATFTAVNWTPLHDNMYEAAGGDKK
                     FYREGVFVNGAAQGYLIDKKTADQYKITNIAQLKDPKIAKLFDTNGDGKADLTGCNPG
                     WGCEGAINHQLAAYGLTNTVTHNQGNYAAMMADTISRYKEGKPVFYYTWTPYWVSNEL
                     KPGKDVVWLQVPFSALPGDKNADTKLPNGANYGFPVSTMHIVANKAWAEKNPAAAKLF
                     AIMQLPVADINAQNAIMHDGKASEGDIQGHVDGWIKAHQQQFDGWVNEALAAQK"
     gene            3479..4663
                     /locus_tag="IRB70_000542"
     CDS             3479..4663
                     /locus_tag="IRB70_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630496.1"
                     /translation="MTKPNHELSPALIVLMSIATGLAVASNYYAQPLLDTIARNFSLS
                     ASSAGFIVTAAQLGYAAGLLFLVPLGDMFERRRLIVSMTLLAAGGMLITASSQSLAMM
                     ILGTALTGLFSVVAQILVPLAATLASPDKRGKVVGTIMSGLLLGILLARTVAGLLASL
                     GGWRTVFWVASVLMALMALALWRGLPQMKSETHLNYPQLLGSVFSMFISNKILRTRAL
                     LGCLTFANFSILWTSMAFLLAAPPFNYSDGVIGLFGLAGAAGALGARPAGGFADKGKS
                     HHTTTFGLLLLLLSWLAIWFGHTSVLALVIGILVLDLTVQGVHITNQTVIYRIYPDAR
                     NRLTAGYMTSYFIGGAAGSLISASAWQHGGWAGVCLAGATIALVNLLVWWRGFHRQEA
                     AN"
     gene            4787..5524
                     /gene="ygaZ"
                     /locus_tag="IRB70_000543"
     CDS             4787..5524
                     /gene="ygaZ"
                     /locus_tag="IRB70_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine exporter subunit YgaZ"
                     /protein_id="HBC0630497.1"
                     /translation="MESPTPQPAPGSATFMEGCKDSLPIVISYIPVAFAFGLNATRLG
                     FSPLESVFFSCIIYAGASQFVITAMLAAGSSLWVAALTVMAMDVRHVLYGPSLRSRII
                     QRLQKSKTALWAFGLTDEVFAAATAKLVRNNRRWSENWMIGIAFSSWSSWVFGTVIGA
                     FSGSGLLQGYPAVEAALGFMLPALFMSFLLASFQRKQSLCVTAALVGALAGVTLFSIP
                     VAILAGIVCGCLTALIQAFWQGAPDEL"
     gene            5514..5849
                     /gene="ygaH"
                     /locus_tag="IRB70_000544"
     CDS             5514..5849
                     /gene="ygaH"
                     /locus_tag="IRB70_000544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-valine transporter subunit YgaH"
                     /protein_id="HBC0630498.1"
                     /translation="MSYEVLLLGLLVGTANYCFRYLPLRLRVGNARPTKRGAIGILLD
                     TIGIASICALLVVSTAPEVMHDTRRFVPTLVGFAVLGASFYKTRSIIIPTLLSALAYG
                     LAWKVMAII"
     gene            5940..6470
                     /gene="emrR"
                     /locus_tag="IRB70_000545"
     CDS             5940..6470
                     /gene="emrR"
                     /locus_tag="IRB70_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter EmrAB
                     transcriptional repressor EmrR"
                     /protein_id="HBC0630499.1"
                     /translation="MDSSFTPIEQMLKFRASRHEDFPYQEILLTRLCMHMQSKLLENR
                     NKMLKAQGINETLFMALITLESQENHSIQPSELSCALGSSRTNATRIADELEKRGWIE
                     RRESDNDRRCLHLQLTEKGHEFLREVLPPQHNCLHQLWSALSTTEKDQLEQITRKLLS
                     RLDQMEQDGAVLEAMS"
     gene            6597..7769
                     /gene="emrA"
                     /locus_tag="IRB70_000546"
     CDS             6597..7769
                     /gene="emrA"
                     /locus_tag="IRB70_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrA"
                     /protein_id="HBC0630500.1"
                     /translation="MSANAETQTPQQPVKKSGKRKRLLLLLTLLFIIIAVAIGIYWFL
                     VLRHFEETDDAYVAGNQIQIMSQVSGSVTKVWADNTDFVKEGDVLVTLDPTDARQAFE
                     KAKTALASSVRQTHQLMINSKQLQANIEVQKIALAKAQSDYNRRVPLGNANLIGREEL
                     QHARDAVTSAQAQLDVAIQQYNANQAMILGTKLEDQPAVQQAATEVRNAWLALERTRI
                     VSPMTGYVSRRAVQPGAQISPTTPLMAVVPATNMWVDANFKETQIANMRIGQSVTITT
                     DIYGDDVKYTGKVVGLDMGTGSAFSLLPAQNATGNWIKVVQRLPVRIELDQKQLEQYP
                     LRIGLSTLVSVNTTNRDGQVLANKVRSTPVAVSTAREISLAPVNKLIDDIVKANAG"
     gene            7786..9324
                     /gene="emrB"
                     /locus_tag="IRB70_000547"
     CDS             7786..9324
                     /gene="emrB"
                     /locus_tag="IRB70_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrB"
                     /protein_id="HBC0630501.1"
                     /translation="MQQQKPLEGAQLVIMTIALSLATFMQVLDSTIANVAIPTIAGNL
                     GSSLSQGTWVITSFGVANAISIPLTGWLAKRVGEVKLFLWSTIAFAIASWACGVSSSL
                     NMLIFFRVIQGIVAGPLIPLSQSLLLNNYPPAKRSIALALWSMTVIVAPICGPILGGY
                     ISDNYHWGWIFFINVPIGVAVVLMTLQTLRGRETRTERRRIDAVGLALLVIGIGSLQI
                     MLDRGKELDWFSSQEIIILTVVAVVAICFLIVWELTDDNPIVDLSLFKSRNFTIGCLC
                     ISLAYMLYFGAIVLLPQLLQEVYGYTATWAGLASAPVGIIPVILSPIIGRFAHKLDMR
                     RLVTFSFIMYAVCFYWRAYTFEPGMDFGASAWPQFIQGFAVACFFMPLTTITLSGLPP
                     ERLAAASSLSNFTRTLAGSIGTSITTTMWTNRESLHHAQLTESVNPFNPNAQAMYSQL
                     EGLGMTQQQASGWIAQQITNQGLIISANEIFWMSAGIFLVLLGLVWFAKPPFGAGGGG
                     GGAH"
     gene            complement(9388..9903)
                     /gene="luxS"
                     /locus_tag="IRB70_000548"
     CDS             complement(9388..9903)
                     /gene="luxS"
                     /locus_tag="IRB70_000548"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008458247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBC0630502.1"
                     /translation="MPLLDSFTVDHTRMEAPAVRVAKTMNTPHGDAITVFDLRFCVPN
                     KEVMPERGIHTLEHLFAGFMRNHLNGNGVEIIDISPMGCRTGFYMSLIGTPDEQRVAD
                     AWKAAMEDVLKVQDQNQIPELNVYQCGTYQMHSLQEAQDIARSILERDVRINSNEELA
                     LPKEKLQELHI"
     gene            complement(10053..11609)
                     /gene="gshA"
                     /locus_tag="IRB70_000549"
     CDS             complement(10053..11609)
                     /gene="gshA"
                     /locus_tag="IRB70_000549"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HBC0630503.1"
                     /translation="MIPDVSQALAWLEKHPQALKGIQRGLERETLRVNADGTLATTGH
                     PEALGSALTHKWITTDFAEALLEFITPVDGDIEHMLTFMRDLHRYTARNMGDERMWPL
                     SMPCYIAEGQDIELAQYGTSNTGRFKTLYREGLKNRYGALMQTISGVHYNFSLPMAFW
                     QAKCGDISGADAKEKISAGYFRVIRNYYRFGWVIPYLFGASPAICSSFLQGKPTSLPF
                     EKTECGMYYLPYATSLRLSDLGYTNKSQSNLGITFNDLYEYVAGLKQAIKTPSEEYAK
                     IGIEKDGKRLQINSNVLQIENELYAPIRPKRVTRSGESPSDALLRGGIEYIEVRSLDI
                     NPFSPIGVDEQQVRFLDLFMVWCALADAPEMSSSELACTRVNWNRVILEGRKPGLTLG
                     IGCETAQFPLPQVGKDLFRDLKRVAQTLDSINGGEAYQKVCDELVACFDNPDLTFSAR
                     ILRSMIDTGIGGTGKAFAEAYRNLLREEPLEILREEDFVAEREASERRQQEMEAADTE
                     PFAVWLEKHA"
     gene            complement(11682..12110)
                     /locus_tag="IRB70_000550"
     CDS             complement(11682..12110)
                     /locus_tag="IRB70_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBC0630504.1"
                     /translation="MSEALSLFSLFASSFLSATLLPGNSEVVLVAMLLSGISHPWVLV
                     LTATMGNSLGGLTNVILGRFFPLRKTSRWQEKATGWLKRYGAVTLLLSWMPVVGDLLC
                     LLAGWMRISWGPVIFFLCLGKALRYVAVAAATVQGMMWWH"
     gene            complement(12107..12673)
                     /gene="yqaB"
                     /locus_tag="IRB70_000551"
     CDS             complement(12107..12673)
                     /gene="yqaB"
                     /locus_tag="IRB70_000551"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-1-phosphate/6-phosphogluconate
                     phosphatase"
                     /protein_id="HBC0630505.1"
                     /translation="MYERYAGLIFDMDGTILDTEPTHRKAWREVLGHYGLQYDVQAMI
                     ALNGSPTWRIAQAIIELNQADLDPHALAREKTEAVRSMLLDSVEPLPLVEVVKSWHGR
                     RPMAVGTGSESAIAEALLAHLGLRRYFDAVVAADHVKHHKPAPDTFLLCAQRMGVQPT
                     QCVVFEDADFGIQAARAAGMDAVDVRLL"
     gene            complement(12953..13029)
                     /locus_tag="IRB70_000552"
     tRNA            complement(12953..13029)
                     /locus_tag="IRB70_000552"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(12993..12995),aa:Arg,seq:acg)
     gene            complement(13093..13169)
                     /locus_tag="IRB70_000553"
     tRNA            complement(13093..13169)
                     /locus_tag="IRB70_000553"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13133..13135),aa:Arg,seq:acg)
     gene            complement(13234..13310)
                     /locus_tag="IRB70_000554"
     tRNA            complement(13234..13310)
                     /locus_tag="IRB70_000554"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13274..13276),aa:Arg,seq:acg)
     gene            complement(13314..13406)
                     /locus_tag="IRB70_000555"
     tRNA            complement(13314..13406)
                     /locus_tag="IRB70_000555"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(13370..13372),aa:Ser,seq:gct)
     gene            complement(13722..13907)
                     /gene="csrA"
                     /locus_tag="IRB70_000556"
     CDS             complement(13722..13907)
                     /gene="csrA"
                     /locus_tag="IRB70_000556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon storage regulator CsrA"
                     /protein_id="HBC0630506.1"
                     /translation="MLILTRRVGETLMIGDEVTVTVLGVKGNQVRIGVNAPKEVSVHR
                     EEIYQRIQAEKSQQSSY"
     gene            complement(14142..16772)
                     /gene="alaS"
                     /locus_tag="IRB70_000557"
     CDS             complement(14142..16772)
                     /gene="alaS"
                     /locus_tag="IRB70_000557"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBC0630507.1"
                     /translation="MSKSTAEIRQAFLDFFHSKGHQVVASSSLVPHNDPTLLFTNAGM
                     NQFKDVFLGLDKRNYSRATTSQRCVRAGGKHNDLENVGYTARHHTFFEMLGNFSFGDY
                     FKHDAIQFAWELLTSEKWFALPKERLWVTVYESDDEAYEIWEKEVGIPRERIIRIGDN
                     KGAPYASDNFWQMGDTGPCGPCTEIFYDHGDHIWGGPPGSPEEDGDRYIEIWNIVFMQ
                     FNRQADGTMEPLPKPSVDTGMGLERIAAVLQHVNSNYDIDLFRTLIQAVAKVTGATDL
                     SNKSLRVIADHIRSCAFLIADGVMPSNENRGYVLRRIIRRAVRHGNMLGAKETFFYKL
                     VGPLIDVMGSAGEDLKRQQAQVEQVLKTEEEQFARTLERGLALLDEELAKLSGDTLDG
                     ETAFRLYDTYGFPVDLTADVCRERNIKVDEAGFEAAMEEQRRRAREASGFGADYNAMI
                     RVDSASEFKGYDHLELNGKVTALFVDGKAVDAVNAGQEAVVVLDQTPFYAESGGQVGD
                     KGELKGANFSFAVEDTQKYGQAIGHIGKLATGSLKVGDAVQADVDEARRARIRLNHSA
                     THLMHAALRQVLGTHVSQKGSLVNDKVLRFDFSHNEAMKPEEIRAVEDLVNAQIRRNL
                     PIETNIMDLEAAKAKGAMALFGEKYDERVRVLSMGDFSTELCGGTHASRTGDIGLFRI
                     ISESGTAAGVRRIEAVTGEGAIATVHADSDRLSEVAHLLKGDSNNLADKVRSVLERTR
                     QLEKELQQLKEQAAAQESANLSSKAIDVNGVKLLVSELSGVEPKMLRTMVDDLKNQLG
                     STIIVLATVAEGKVSLIAGVSKDVTDRVKAGELIGMVAQQVGGKGGGRPDMAQAGGTD
                     AAALPAALASVKGWVSAKLQ"
     gene            complement(16901..17401)
                     /gene="recX"
                     /locus_tag="IRB70_000558"
     CDS             complement(16901..17401)
                     /gene="recX"
                     /locus_tag="IRB70_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBC0630508.1"
                     /translation="MTESTSRRPAYARLLDRAVRILAVRDHSEQELRRKLAAPIMGKN
                     GPEEIDATAEDYERVIAWCHEHGYLDDSRFVARFIASRSRKGYGPARIRQELNQKGIS
                     REATEKAMRECDIDWCELARDQATRKYGEPLPTAFSEKVKIQRFLLYRGYLMEDIQDI
                     WRNFAD"
     gene            complement(17470..18531)
                     /gene="recA"
                     /locus_tag="IRB70_000559"
     CDS             complement(17470..18531)
                     /gene="recA"
                     /locus_tag="IRB70_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBC0630509.1"
                     /translation="MAIDENKQKALAAALGQIEKQFGKGSIMRLGEDRSMDVETISTG
                     SLSLDIALGAGGLPMGRIVEIYGPESSGKTTLTLQVIAAAQREGKTCAFIDAEHALDP
                     IYARKLGVDIDNLLCSQPDTGEQALEICDALARSGAVDVIVVDSVAALTPKAEIEGEI
                     GDSHMGLAARMMSQAMRKLAGNLKQSNTLLIFINQIRMKIGVMFGNPETTTGGNALKF
                     YASVRLDIRRIGAVKEGENVVGSETRVKVVKNKIAAPFKQAEFQILYGEGINFYGELV
                     DLGVKEKLIEKAGAWYSYKGEKIGQGKANATAWLKDNPETAKEIEKKVRELLLSNPNS
                     TPDFSVDDSEGVAETNEDF"
     gene            complement(18611..19108)
                     /gene="pncC"
                     /locus_tag="IRB70_000560"
     CDS             complement(18611..19108)
                     /gene="pncC"
                     /locus_tag="IRB70_000560"
                     /EC_number="3.5.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide-nucleotide amidase"
                     /protein_id="HBC0630510.1"
                     /translation="MTDSELMQLSEQVGQALKARGATVTTAESCTGGWVAKVITDIAG
                     SSAWFERGFVTYSNEAKAQMIGVREETLAQHGAVSEPVVVEMAIGALKAARADYAVSI
                     SGIAGPDGGSEEKPVGTVWFAFATARGEGITRRECFSGDRDAVRRQATAYALQTLWQQ
                     FLQNT"
     gene            complement(19253..20338)
                     /gene="mltB"
                     /locus_tag="IRB70_000561"
     CDS             complement(19253..20338)
                     /gene="mltB"
                     /locus_tag="IRB70_000561"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic murein transglycosylase B"
                     /protein_id="HBC0630511.1"
                     /translation="MFKRRYVTLLPLFVLLAACSSKPKPTETETTTGTPSGGFLLEPQ
                     HNVMQMGGDFANNPNAQQFIDKMVNKHGFNRQQLQEILSQAKRLDSVLRLMDNQAPTT
                     SVKPPSGPNGAWLRYRKKFITPDNVQNGVVFWNQYEDALNRAWQVYGVPPEIIVGIIG
                     VETRWGRVMGKTRILDALATLSFNYPRRAEYFSGELETFLLMARDEQDDPLNLKGSFA
                     GAMGYGQFMPSSYKQYAVDFSGDGHINLWDPVDAIGSVANYFKAHGWVKGDQVAVMAN
                     GQAPGLPNGFKTRYSISQLAAAGLTPQQPLGNHQQASLLRLDVGTGYQYWYGLPNFYT
                     ITRYNHSTHYAMAVWQLGQAVALARVQ"
     gene            20595..21158
                     /gene="srlA"
                     /locus_tag="IRB70_000562"
                     /gene_synonym="gutA"
     CDS             20595..21158
                     /gene="srlA"
                     /locus_tag="IRB70_000562"
                     /gene_synonym="gutA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBC0630512.1"
                     /translation="MIETITHGAEWFIGLFQKGGEVFTGMVTGILPLLISLLVIMNAL
                     INFIGQHRIERFAQRCAGNPVSRYLLLPCIGTFVFCNPMTLSLGRFMPEKYKPSYYAA
                     ASYSCHSMNGLFPHINPGELFVYLGIASGLTTLNLPLGPLAVSYLLVGLVTNFFRGWV
                     TDLTTAIFEKKMGIQLEQKVHLAGATS"
     gene            21155..22114
                     /gene="srlE"
                     /locus_tag="IRB70_000563"
                     /gene_synonym="gutE"
     CDS             21155..22114
                     /gene="srlE"
                     /locus_tag="IRB70_000563"
                     /gene_synonym="gutE"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBC0630513.1"
                     /translation="MTRIRIEKGTGGWGGPLELEAKPGKKIVYITAGTRPAIVDKLAQ
                     LTGWQAIDGFKEGEPAEAEIGVAVIDCGGTLRCGIYPKRRIPTINIHSTGKSGPLAQY
                     IVEDIYVSGVKEENITVVGDATPQPSSVGRDYDTSKKITEQSDGLLAKVGMGMGSAVA
                     VLFQSGRDTIDTVLKTILPFMAFVSALIGIIMASGLGDWIAHGLAPLASHPLGLVMLA
                     LICSFPLLSPFLGPGAVIAQVIGVLIGVQIGLGNIPPHLALPALFAINAQAACDFIPV
                     GLSLAEARQDTVRVGVPSVLVSRFLTGAPTVLIAWFVSGFIYQ"
     gene            22125..22496
                     /gene="srlB"
                     /locus_tag="IRB70_000564"
                     /gene_synonym="gutB"
     CDS             22125..22496
                     /gene="srlB"
                     /locus_tag="IRB70_000564"
                     /gene_synonym="gutB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBC0630514.1"
                     /translation="MTVIYQTTITRIGASATDALSDQMLITFREGAPADLEEYCFIHC
                     HGELKGALHPGLQFSLGQHRYPVTAVGSVAEDNLRELGHVTLRFDGLNEAEFPGTVHV
                     AGPVPDDIAPGSVLKFESVKE"
     gene            22500..23279
                     /gene="srlD"
                     /locus_tag="IRB70_000565"
     CDS             22500..23279
                     /gene="srlD"
                     /locus_tag="IRB70_000565"
                     /EC_number="1.1.1.140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sorbitol-6-phosphate dehydrogenase"
                     /protein_id="HBC0630515.1"
                     /translation="MNQVAVVIGGGQTLGAFLCHGLAAEGYRVAVVDIQSDKAANVAQ
                     EINAEYGEGTAYGFGADATSEQSVLALSRGVDEIFGRVDLLVYSAGIAKAAFISDFQL
                     GDFDRSLQVNLVGYFLCAREFSRLMIRDGIQGRIIQINSKSGKVGSKHNSGYSAAKFG
                     GVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSLLPQYATKLGIKPDQVEQYYIDK
                     VPLKRGCDYQDVLNMLLFYASPKASYCTGQSINVTGGQVMF"
     gene            23385..23744
                     /gene="gutM"
                     /locus_tag="IRB70_000566"
     CDS             23385..23744
                     /gene="gutM"
                     /locus_tag="IRB70_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator GutM"
                     /protein_id="HBC0630516.1"
                     /translation="MVSALITVAVIAWCAQLALGGWQISRFNRAFDTLCQQGRVGVGR
                     SSGRFKPRVVVAIALDDQQRIVDTLFMKGLTVFARPQKIPAITGMHAGDLQPDVIFPH
                     DPLSQNALSLALKLKRG"
     gene            23811..24584
                     /gene="srlR"
                     /locus_tag="IRB70_000567"
                     /gene_synonym="gutR"
     CDS             23811..24584
                     /gene="srlR"
                     /locus_tag="IRB70_000567"
                     /gene_synonym="gutR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucitol operon DNA-binding transcriptional
                     repressor SrlR"
                     /protein_id="HBC0630517.1"
                     /translation="MKPRQRQAAILEYLQKQGKCSVEELAQYFDTTGTTIRKDLVILE
                     HAGTVIRTYGGVVLNKEESDPPIDHKTLINTHKKELIAEAAVSFIHDGDSIILDAGST
                     VLQMVPLLSRFNNITVMTNSLHIVNALSELDNEQTILMPGGTFRKKSASFHGQLAENA
                     FEHFTFDKLFMGTDGIDLNAGVTTFNEVYTVSKAMCNAAREVILMADSSKFGRKSPNV
                     VCSLESVDKLITDAGIDPAFRQALEKKGIDVIITGESNE"
     gene            24577..25542
                     /gene="gutQ"
                     /locus_tag="IRB70_000568"
     CDS             24577..25542
                     /gene="gutQ"
                     /locus_tag="IRB70_000568"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311591.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase GutQ"
                     /protein_id="HBC0630518.1"
                     /translation="MSEALLNAGRQTLMLELQEASRLPERLGDDFVRAANIILHCEGK
                     VVVSGIGKSGHIGKKIAATLASTGTPAFFVHPAEALHGDLGMIESRDVMLFISYSGGA
                     KELDLIIPRLEDKSIALLAMTGKPTSPLGLAAKAVLDISVEREACPMHLAPTSSTVNT
                     LMMGDALAMAVMQARGFNEEDFARSHPAGALGARLLNKVHHLMRRDDAIPQVALTASV
                     MDAMLELSRTGLGLVAVCDAQQQVQGVFTDGDLRRWLVGGGALTTPVNEAMTVGGTTL
                     QSQSRAIDAKEILMKRKITAAPVVDENGKLTGAINLQDFYQAGII"
     gene            complement(25539..27053)
                     /gene="norR"
                     /locus_tag="IRB70_000569"
     CDS             complement(25539..27053)
                     /gene="norR"
                     /locus_tag="IRB70_000569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311592.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide reductase transcriptional regulator
                     NorR"
                     /protein_id="HBC0630519.1"
                     /translation="MSFSVDVLANIAIELQRGIGHQDRFQRLITTLRQVLECDASALL
                     RYDSRQFIPLAIDGLAKDVLGRRFALEGHPRLEAIARAGDVVRFPADSELPDPYDGLI
                     PGQESLKVHACVGLPLFAGQNLIGALTLDGMQPDQFDVFSDEELRLIAALAAGALSNA
                     LLIEQLESQNMLPGDAAPFEAVKQTQMIGLSPGMTQLKKEIEIVAASDLNVLISGETG
                     TGKELVAKAIHETSPRAVNPLVYLNCAALPESVAESELFGHVKGAFTGAISNRSGKFE
                     MADNGTLFLDEIGELSLALQAKLLRVLQYGDIQRVGDDRSLRVDVRVLAATNRDLREE
                     VLAGRFRADLFHRLSVFPLSVPPLRERGDDVILLAGYFCEQCRLRLGLSRVVLSAGAR
                     NLLQHYSFPGNVRELEHAIHRAVVLARATRSGDEVILEAQHFAFPEVTLPPPEAAAVP
                     IVKQNLREATEAFQRETIRQALAQNHHNWAASARMLETDVANLHRLAKRLGLKD"
     gene            27240..28679
                     /gene="norV"
                     /locus_tag="IRB70_000570"
     CDS             27240..28679
                     /gene="norV"
                     /locus_tag="IRB70_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic nitric oxide reductase
                     flavorubredoxin"
                     /protein_id="HBC0630520.1"
                     /translation="MSIVVKNNIHWVGQRDWEVRDFHGTEYKTLRGSSYNSYLIREEK
                     NVLIDTVDHKFSREFVQNLRNEIDLADIDYIVINHAEEDHAGALTELMAQIPDTPIYC
                     TANAIDSINGHHHHPEWNFNVVKTGDTLDIGNGKQLIFVETPMLHWPDSMMTYLTGDA
                     VLFSNDAFGQHYCDEHLFNDEVDQTELFEQCQRYYANILTPFSRLVTPKITEILGFNL
                     PVDMIATSHGVVWRDNPTQIVELYLKWAADYQEDRITIFYDTMSNNTRMMADAIAQGI
                     AETDPRVAVKIFNVARSDKNEILTNVFRSKGVLVGTSTMNNVMMPKIAGLVEEMTGLR
                     FRNKRASAFGSHGWSGGAVDRLSTRLQDAGFEMSLSLKAKWRPDQDALELCREHGREI
                     ARQWALAPLPQSTVNTVVKEETSAATTADLGPRMQCSVCQWIYDPAKGEPMQDVAPGT
                     PWSEVPDNFLCPECSLGKDVFDELASEAK"
     gene            28676..29809
                     /gene="norW"
                     /locus_tag="IRB70_000571"
     CDS             28676..29809
                     /gene="norW"
                     /locus_tag="IRB70_000571"
                     /EC_number="1.18.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH:flavorubredoxin reductase NorW"
                     /protein_id="HBC0630521.1"
                     /translation="MSNGIVIIGSGFAARQLVKNIRKQDASIPLTLIAADSMDEYNKP
                     DLSHVISQGQRADDLTRQTAGEFAEQFNLRLFPHTWVTDIDAEAHVVKSQNNQWQYDK
                     LVLATGASAFVPPVPGRELMLTLNSQQEYRACETQLRDARRVLIVGGGLIGSELAMDF
                     CRAGKAVTLIDNAASILASLMPPEVSSRLQHRLTEMGVHLLLKSQLQGLEKTDSGILA
                     TLDRQRCIEVDAVIAATGLRPETALARRAGLTINRGVCVDSYLQTSNADIYALGDCAE
                     INGQVLPFLQPIQLSAMVLAKNLLGNNTPLKLPAMLVKIKTPELPLHLAGETQRQDLR
                     WQINTERQGMVARGVDDADQLRAFVVSEDRMKEAFGLLKTLPM"
     gene            complement(29888..32128)
                     /gene="hypF"
                     /locus_tag="IRB70_000572"
     CDS             complement(29888..32128)
                     /gene="hypF"
                     /locus_tag="IRB70_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyltransferase HypF"
                     /protein_id="HBC0630522.1"
                     /translation="MAKNTSCGVQLRIRGKVQGVGFRPFVWQLAQQLNLHGDVCNDGD
                     GVEVRLLEDPETFLVQLHQHCPPLARIDSVEREPFIWSQLPTEFTIRQSTGGTMNTQI
                     VPDAATCPACLAEMNTPGERRYRYPFINCTHCGPRFTIIRAMPYDRPFTVMAAFPLCP
                     ACDKEYCDPLDRRFHAQPVACPECGPHLEWVSHGEHAEQEAALQAAIAQLKMGNIVAI
                     KGIGGFHLACDARNSNAVATLRARKHRPAKPLAVMLPVADGLPDAARQLLTTPAAPIV
                     LVDKKYVPELCDDIAPGLNEVGVMLPANPLQHLLLQELQCPLVMTSGNLNGKPPAISN
                     EQALADLQGIADGFLIHNRDIVQRMDDSVVRENGEMLRRSRGYVPDALALPPGFKNVP
                     PVLCLGADLKNTFCLVRGKQAVLSQHLGDLSDDGIQMQWREALRLMQNIYDFTPQYVV
                     HDAHPGYVSSQWAREMNLPTQTVLHHHAHAAACLAEHHWPLDGGDVIALTLDGIGMGE
                     NGALWGGECLRVNYRECEHLGGLPAVALPGGDLAAKQPWRNLLAQCLRFVPEWQNYPE
                     TASVQQQNWSVLARAIERGINAPLASSCGRLFDAVAAALGCAPATLSYEGEAACALEA
                     LAASSQGVTHPVTMPLVDNQLDLATFWQQWLNWQAPVNQRAWAFHDALAQGFAALMRE
                     QATMRGITTLVFSGGVIHNRLLRTRLAHYLADFTLLFPQSLPAGDGGLSLGQGVIAAA
                     RILHAA"
     gene            complement(32281..32808)
                     /gene="hydN"
                     /locus_tag="IRB70_000573"
     CDS             complement(32281..32808)
                     /gene="hydN"
                     /locus_tag="IRB70_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transport protein HydN"
                     /protein_id="HBC0630523.1"
                     /translation="MNRFIIADASKCIGCRTCEVACVVSHQENQDCASLTPETFLPRI
                     HVIKGVNISTATVCRQCEDAPCANVCPNGAISRDKGFVHVMQERCIGCKTCVVACPYG
                     AMEVVVRPVIRNSGAGLNVRADKAEANKCDLCNHREDGPACMAACPTHALICVDRNKL
                     EQLSAEKRRRTALMF"
     gene            complement(32957..33967)
                     /gene="ascG"
                     /locus_tag="IRB70_000574"
     CDS             complement(32957..33967)
                     /gene="ascG"
                     /locus_tag="IRB70_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator AscG"
                     /protein_id="HBC0630524.1"
                     /translation="MTTMLEVAKRAGVSKATVSRVLSGNGYVSQETKDRVFQAVEESG
                     YRPNLLARNLSAKSTQTLGLVVTNTLYHGIYFSELLFHAARMAEEKGRQLLLADGKHS
                     AEEERQAIQYLLDLRCDAIMIYPRFLSVDEIDDIIDAHSQPIMVLNRRLRKNSSHSVW
                     CDHKQTSFNAVAELINAGHQEIAFLTGSMDSPTSVERLAGYKDALAQHGIALNEKLIA
                     NGKWTPASGAEGVETLLERGAKFSALVASNDDMAIGAMKALHERGVAVPEQVSVIGFD
                     DIAIAPYTVPALSSVKIPVTEMIQEIIGRLIFMLDGGDFSPPKTFSGKLIRRGSLIAL
                     SQ"
     gene            34226..35683
                     /gene="ascF"
                     /locus_tag="IRB70_000575"
     CDS             34226..35683
                     /gene="ascF"
                     /locus_tag="IRB70_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose/arbutin/salicin transporter
                     subunit IIBC"
                     /protein_id="HBC0630525.1"
                     /translation="MAKNYAALARSVIAALGGVDNISAVTHCMTRLRFVIKDDQLIDS
                     PTLKTIPGVLGVVRSDNQCQVIIGNTVSQAFQEVVSLLPGDMQPAQPVGKPKLTLRRI
                     GAGILDALIGTMSPLIPAIIGGSMVKLLAMILEMSGVLTKGSPTLTILNVIGDGAFFF
                     LPLMVAASAAIKFKTNMSLAIAIAGVLVHPSFIELMAKAAQGEHVEFALIPVTAVKYT
                     YTVIPALVMTWCLSYIERWVDSITPAVTKNFLKPMLIVLIAAPLAILLIGPIGIWIGS
                     AISALVYTIHGYLGWLSVAIMGALWPLLVMTGMHRVFTPTIIQTIAETGKEGMVMPSE
                     IGANLSLGGSSLAVAWKTKNPELRQTALAAAASAIMAGISEPALYGVAIRLKRPLIAS
                     LISGFICGAVAGMAGLASHSMAAPGLFTSVQFFDPANPMSIVWVFAVMALAVVLSFIL
                     TLLLGFEDIPVEEATAEVRKHQSAQPTVAKEVSLN"
     gene            35692..37116
                     /gene="ascB"
                     /locus_tag="IRB70_000576"
     CDS             35692..37116
                     /gene="ascB"
                     /locus_tag="IRB70_000576"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase AscB"
                     /protein_id="HBC0630526.1"
                     /translation="MSVFPEGFLWGGALAANQSEGAYREGGKGLTTVDMIPHGEHRMA
                     VKLGLEKRFQLRDDEFYPSHEATDFYHRYKEDIALMAEMGFKVFRTSIAWSRLFPQGD
                     ELTPNQQGIAFYRAVFEECKKYGIEPLVTLCHFDVPMHLVTEYSSWRNRKLVEFFSRY
                     ARTCFEAFNGLVKYWLTFNEINIMLHSPFSGAGLVFEEGENQDQVKYQAAHHQLVASA
                     LATKIAHEVNPQNQVGCMLAGGNFYPYSCKPEDVWAALEKDRENLFLIDVQARGAYPA
                     YSARVFREKGVTINKAPGDDEILKNTVDFVSFSYYASRCASAEMNANNSSAANVVKSL
                     RNPYLQVSDWGWGIDPLGLRITMNMMYDRYQKPLFLVENGLGAKDEFAANGEINDDYR
                     ISYLREHIRAMGEAIADGIPLMGYTTWGCIDLVSASTGEMSKRYGFVYVDRDDAGNGT
                     LARTRKKSFWWYKKVIASNGEDLE"
     gene            complement(37195..37614)
                     /locus_tag="IRB70_000577"
     CDS             complement(37195..37614)
                     /locus_tag="IRB70_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001696729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0630527.1"
                     /translation="MTANAARAVKATRELVNAVPFLGGSDSEDDYREALELVEYLIEE
                     DDTNPLIDFLASRIAEYENNNEKFAEFDKAVAAMPVGVALLHTLIDQHNLTYADLKNE
                     IGSKSLVSQILSGQRSLTISHIKALSARFGVKPEWFL"
     gene            complement(37640..37825)
                     /locus_tag="IRB70_000578"
     CDS             complement(37640..37825)
                     /locus_tag="IRB70_000578"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630528.1"
                     /translation="MNIRTGMCAFLLSLVLPAQATSFTEYLPMSDSEYAQKRALKPLL
                     TMPYDAEQTWHFRKVGV"
     gene            complement(37850..38320)
                     /gene="hycI"
                     /locus_tag="IRB70_000579"
     CDS             complement(37850..38320)
                     /gene="hycI"
                     /locus_tag="IRB70_000579"
                     /EC_number="3.4.23.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation peptidase HycI"
                     /protein_id="HBC0630529.1"
                     /translation="MTDVLLCVGNSMMGDDGAGPLLAEKCAAAPKGNWVVIDGGSAPE
                     NDIVAIRELRPTRLLIVDATDMGLNPGEIRIIDPDDIAEMFMMTTHNMPLNYLIDQLK
                     EDIGEVIFLGIQPDIVGFYYPMTQPIKDAVETVYQRLEGWEGNGGFAQLAVEEE"
     gene            complement(38313..38723)
                     /gene="hycH"
                     /locus_tag="IRB70_000580"
     CDS             complement(38313..38723)
                     /gene="hycH"
                     /locus_tag="IRB70_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase assembly protein HycH"
                     /protein_id="HBC0630530.1"
                     /translation="MIEKVVFSQLSRKFIDENDATPAEAQQVVYYSLAIGHHLGVIDC
                     LEAALTCPWDDYLAWIATLEAGSEARRKMEGVPKYGEIVIDINHVPMLANAFDKARAA
                     QTSQQKEWSTMLLSMLHDIHQENAIYLMVRRLRD"
     gene            complement(38720..39487)
                     /gene="hycG"
                     /locus_tag="IRB70_000581"
     CDS             complement(38720..39487)
                     /gene="hycG"
                     /locus_tag="IRB70_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycG"
                     /protein_id="HBC0630531.1"
                     /translation="MSNLLGPRDANGIPVPMTVDESIASMKASLLKKIKRSAYVYRVD
                     CGGCNGCEIEIFATLSPLFDAERFGIKVVPSPRHADILLFTGAVTRAMRSPALRAWQS
                     APDPKICISYGACGNSGGIFHDLYCVWGGTDKIVPVDVYIPGCPPTPAATLYGFAMAL
                     GLLEQKIHARGPGEQDEQPAEILHGDMVQPLRVKVDREARRLAGYRYGRQIADDFLTQ
                     LGQGEEQVARWLEAENDPRLNEIVSHLNHVVEEARIR"
     gene            complement(39487..40029)
                     /gene="hycF"
                     /locus_tag="IRB70_000582"
     CDS             complement(39487..40029)
                     /gene="hycF"
                     /locus_tag="IRB70_000582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycF"
                     /protein_id="HBC0630532.1"
                     /translation="MFTFIKKVIKTGTATSSYPLEPIAVDKNFRGKPEQNPQQCIGCA
                     ACVNACPSNALTVETDLATGELAWQFNLGRCIFCGRCEEVCPTAAIKLSQEYELAVWK
                     KEDFLQQSRFALCNCRVCNRPFAVQKEIDYAIALLKHNGDSRAENHRESFETCPECKR
                     QKCLVPSDRIELTRHMKEAI"
     gene            complement(40039..41748)
                     /gene="hycE"
                     /locus_tag="IRB70_000583"
     CDS             complement(40039..41748)
                     /gene="hycE"
                     /locus_tag="IRB70_000583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycE"
                     /protein_id="HBC0630533.1"
                     /translation="MSEEKLGQHYLAALNEAFPGVVLDHAWQTKDQLTVTVKVNYLPE
                     VVEFLYYKQGGWLSVLFGNDERKLNGHYAVYYVLSMEKGTKCWITVRVEVDANKPEYP
                     SVTPRVPAAVWGEREVRDMYGLIPVGLPDERRLVLPDDWPDELYPLRKDSMDYRQRPA
                     PTTDAETYEFINELGDKKNNVVPIGPLHVTSDEPGHFRLFVDGENIIDADYRLFYVHR
                     GMEKLAETRMGYNEVTFLSDRVCGICGFAHSTAYTTSVENAMGIQVPERAQMIRAILL
                     EVERLHSHLLNLGLACHFTGFDSGFMQFFRVRETSMKMAEILTGARKTYGLNLIGGIR
                     RDLLKDDMIQTRQLAQQMRREVQELVDVLLSTPNMEQRTVGIGRLDPEIARDFSNVGP
                     MVRASGHARDTRADHPFVGYGLLPMEVHSEQGCDVISRLKVRINEVYTALNMIDYGLD
                     NLPGGPLMVEGFTYIPHRFALGFAEAPRGDDIHWSMTGDNQKLYRWRCRAATYANWPT
                     LRYMLRGNTVSDAPLIIGSLDPCYSCTDRMTVVDVRKKKSKVVPYKELERYSIERKNS
                     PLK"
     gene            complement(41766..42689)
                     /gene="hycD"
                     /locus_tag="IRB70_000584"
     CDS             complement(41766..42689)
                     /gene="hycD"
                     /locus_tag="IRB70_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycD"
                     /protein_id="HBC0630534.1"
                     /translation="MSVLYPLIQALVLFAVAPLLSGITRVARARLHNRRGPGVLQEYR
                     DIIKLLGRQSVGPDASGWVFRLTPYVMVGVMLTIATALPVVTVGSPLPQLGDLITLLY
                     LFAIARFFFAISGLDTGSPFTAIGASREAMLGVLVEPMLLLGLWVAAQVAGSTNISNI
                     TDTVYHWPLSQSIPLVLALCACAFATFIEMGKLPFDLAEAEQELQEGPLSEYSGSGFG
                     VMKWGISLKQLVVLQMFVGVFIPWGQMETFTVGGLLLALVIAIVKLVVGVLVIALFEN
                     SMARLRLDITPRITWAGFGFAFLAFVSLLAA"
     gene            complement(42692..44518)
                     /gene="hycC"
                     /locus_tag="IRB70_000585"
     CDS             complement(42692..44518)
                     /gene="hycC"
                     /locus_tag="IRB70_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit 3"
                     /protein_id="HBC0630535.1"
                     /translation="MSAISLINSGVAWFVAAAVLAFLFSFQKALSGWIAGIGGAVGGL
                     YTAAAGFTVLTGAVGVSGALSLVSYDVQISPLNAIWLITLGLCGLFISLYNIDWHRHA
                     QVKCNGLQINMLMAAAVCAVIASNLGMFVVMAEIMALCAVFLTSNSKEGKLWFALGRL
                     GTLLLAIACWLLWQRYGTLDLRLLDMRMQQLPLGSDIWLLGVIGFGLLAGIIPLHGWV
                     PQAHANASAPAAALFSTVVMKIGLLGILTLSLLGGNAPLWWGIALLVLGMITAFVGGL
                     YALMEHNIQRLLAYHTLENIGIILLGLGAGVTGIALEQPALIALGLVGGLYHLLNHSL
                     FKSVLFLGAGSVWFRTGHRDIEKLGGIGKKMPVISIAMLVGLMAMAALPPLNGFAGEW
                     VIYQSFFKLSNSGAFVARLLGPLLAVGLAITGALAVMCMAKVYGVTFLGAPRTKEAEN
                     ATCAPLLMSVSVVALAICCVIGGVAAPWLLPMLSAAVPLPLEPANTTVSQPMITLLLI
                     ACPLLPFIIMAICKGDRLPSRSRGAAWVCGYDHEKSMVITAHGFAMPVKQAFAPVLKL
                     RKWLNPVSLVPGWQCEGSALLFRRMALVELAVLVVIIVSRGA"
     gene            complement(44515..45126)
                     /gene="hycB"
                     /locus_tag="IRB70_000586"
     CDS             complement(44515..45126)
                     /gene="hycB"
                     /locus_tag="IRB70_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase subunit HycB"
                     /protein_id="HBC0630536.1"
                     /translation="MNRFVIADSTLCIGCHTCEAACSETHRQHGLQSMPRLRVMLNEK
                     ESAPQLCHHCEDAPCAVVCPVNAITRVDGAVQLNESLCVSCKLCGIACPFGAIEFSGS
                     RPLDIPANANTPKAPPAPPAPARVSTLLDWVPGIRAIAVKCDLCSFDEQGPACVRMCP
                     TKALHLVDNTDIARVSKRKRELTFNTDFGDLTLFQQAQSGEAK"
     gene            complement(45251..45712)
                     /gene="hycA"
                     /locus_tag="IRB70_000587"
     CDS             complement(45251..45712)
                     /gene="hycA"
                     /locus_tag="IRB70_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase regulator HycA"
                     /protein_id="HBC0630537.1"
                     /translation="MTIWEISEKADYIAQRHRRLQDQWHIYCNSLVQGITLSKARLHH
                     AMSCAPDKELCFVLFEHFRIYVTLADGFNSHTIEYYVETKEGEDKQRIAQAQLSIDGM
                     IDGKVNIRDREQVLEHYLEKIAGVYDSLYTAIENNVPVNLSQLVKGQSPAA"
     gene            45924..46274
                     /gene="hypA"
                     /locus_tag="IRB70_000588"
     CDS             45924..46274
                     /gene="hypA"
                     /locus_tag="IRB70_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HBC0630538.1"
                     /translation="MHEITLCQRALELIEQQAAKHGAKRVTGVWLKIGAFSCVETSSL
                     AFCFDLVCRGSVAEGCKLHLEEQEAECWCETCQQYVTLLTQRVRRCPQCHGDMLQIVA
                     DDGLQIRRIEIDQE"
     gene            46278..47150
                     /gene="hypB"
                     /locus_tag="IRB70_000589"
     CDS             46278..47150
                     /gene="hypB"
                     /locus_tag="IRB70_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase nickel incorporation protein HypB"
                     /protein_id="HBC0630539.1"
                     /translation="MCTTCGCGEGNLYIEGDEHNPHSAFRSAPFAPAARPKMKITGIK
                     TPEFTPSQTEEGDLHYGHGEAGTHAPGMSQRRMLEVEIDVLDKNNRLAERNRARFAAR
                     KQLVLNLVSSPGSGKTTLLTETLMRLKDSVPCAVIEGDQQTVNDAARIRATGTPAIQV
                     NTGKGCHLDAQMIADAAPRLPLDDNGILFIENVGNLVCPASFDLGEKHKVAVLSVTEG
                     EDKPLKYPHMFAAASLMLLNKVDLLPYLNFDVEKCIACAREVNPEIEIILISATSGEG
                     MDQWLNWLETQRCA"
     gene            47141..47413
                     /gene="hypC"
                     /locus_tag="IRB70_000590"
     CDS             47141..47413
                     /gene="hypC"
                     /locus_tag="IRB70_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 3 maturation protein HypC"
                     /protein_id="HBC0630540.1"
                     /translation="MCIGVPGQIRTIDGNQAKVDVCGIQRDVDLTLVGSYDENGQPRV
                     GQWVLVHVGFAMSVINEAEARDTLDALQNMFDVEPDVGALLYGEEK"
     gene            47413..48534
                     /gene="hypD"
                     /locus_tag="IRB70_000591"
     CDS             47413..48534
                     /gene="hypD"
                     /locus_tag="IRB70_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase formation protein HypD"
                     /protein_id="HBC0630541.1"
                     /translation="MRFVDEYRAPEQVMQLIEHLRERASHLSYTAERPLRIMEVCGGH
                     THAIFKFGLDQLLPENVEFIHGPGCPVCVLPMGRIDTCVEIASHPEVIFCTFGDAMRV
                     PGKQGSLLQAKARGADVRIVYSPMDALKLAQENPTRKVVFFGLGFETTMPTTAITLQQ
                     AKARDVQNFYFFCQHITLIPTLRSLLEQPDNGIDAFLAPGHVSMVIGTDAYNFIASDF
                     HRPLVVAGFEPLDLLQGVVMLVEQKIAAHSKVENQYRRVVPDAGNLLAQQAIADVFCV
                     NGDSEWRGLGVIESSGVHLTPDYQRFDAEAHFRPAPQQVCDDPRARCGEVLTGKCKPH
                     QCPLFGNTCNPQTAFGALMVSSEGACAAWYQYRQQESEA"
     gene            48531..49541
                     /gene="hypE"
                     /locus_tag="IRB70_000592"
     CDS             48531..49541
                     /gene="hypE"
                     /locus_tag="IRB70_000592"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417210.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation carbamoyl dehydratase
                     HypE"
                     /protein_id="HBC0630542.1"
                     /translation="MNNIQLAHGSGGQAMQQLINSLFMEAFANPWLAEQEDQARLDLA
                     QLVAEGDRLAFSTDSYVIDPLFFPGGNIGKLAICGTANDVAVSGAIPRYLSCGFILEE
                     GLPMETLKAVVTSMAETARAAGIAIVTGDTKVVQRGAADKLFINTAGMGAIPANIHWG
                     AQTLTAGDVLLVSGTLGDHGATILNLREQLGLDGELVSDCAVLTPLIQTLRDIPCVKA
                     LRDATRGGVNAVVHEFAEACGCGIEISEAALPVKPAVRGVCELLGLDALNFANEGKLV
                     IAVERNAAEQVLAALHSHPLGKDAALIGEVVERKGVRLAGLYGVKRTLDLPHAEPLPR
                     IC"
     gene            49615..51693
                     /gene="flhA"
                     /locus_tag="IRB70_000593"
     CDS             49615..51693
                     /gene="flhA"
                     /locus_tag="IRB70_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase transcriptional activator
                     FlhA"
                     /protein_id="HBC0630543.1"
                     /translation="MSYTPMSDLGQQGLFDITRTLLQQPDLASLCEALSQLVKRSALA
                     DNAAIVLWQAQTQRASYYASREKDTPIKYEDETVLAHGPVRSILSRPDTLHCSYEEFC
                     ETWPQLAAGGLYPKFGHYCLMPLAAEGHIFGGCEFIRYDDRPWSEKEFNRLQTFTQIV
                     SVVTEQIQSRVVNNVDYELLCRERDNFRILVAITNAVLSRLDMDELVSEVAKEIHYYF
                     DIDDISIVLRSHRKNKLNIYSTHYLDKQHPAHEQSEVDEAGTLTERVFKSKEMLLINL
                     HERDDLAPYERMLFDTWGNQIQTLCLLPLMSGDTMLGVLKLAQCEEKVFTTTNLSLLR
                     QIAERVAIAVDNALAYQEIHRLKERLVDENLALTEQLNNVDSEFGEIIGRSEAMYSVL
                     KQVEMVAQSDSTVLILGETGTGKELIARAIHNLSGRNNRRMVKMNCAAMPAGLLESDL
                     FGHERGAFTGASAQRIGRFELADKSSLFLDEVGDMPLELQPKLLRVLQEQEFERLGSN
                     KIIQTDVRLIAATNRDLKKMVADREFRSDLYYRLNVFPIHLPPLRERPEDIPLLAKAF
                     TFKIARRLGRNIDSIPAETLRILSNMEWPGNVRELENVIERAVLLTRGNVLQLSLPDI
                     ALPEPETPPAATVVAQEGEDEYQLIVRVLKETNGVVAGPKGAAQRLGLKRTTLLSRMK
                     RLGIDKSALI"
     gene            51738..52166
                     /locus_tag="IRB70_000594"
     CDS             51738..52166
                     /locus_tag="IRB70_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012134844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TOBE domain-containing protein"
                     /protein_id="HBC0630544.1"
                     /translation="MAVSARNQLTGTVSAVAMGAVNDEVELTLAGGAKLVAIVTHSSQ
                     QALGLAKGKEAIALIKAPWVTLATEDCGLKFSARNQFAGSVSTITEGAVNATVHIKTD
                     AGFEIVAVVTNESQDEMKLTTGSRVIALIKASAILIATKA"
     gene            complement(52205..52549)
                     /locus_tag="IRB70_000595"
     CDS             complement(52205..52549)
                     /locus_tag="IRB70_000595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrous oxide-stimulated promoter family
                     protein"
                     /protein_id="HBC0630545.1"
                     /translation="MSGKRISREKLTIKKMIDLYQAKCPQASAEPEHYDALFAYAQKR
                     LDKCVFGEEKPACKQCPVHCYQPAKREEMKQIMRWAGPRMLWRHPILTVRHLIDDKRP
                     VPELPEKYRPKK"
     gene            complement(52626..52760)
                     /locus_tag="IRB70_000596"
     CDS             complement(52626..52760)
                     /locus_tag="IRB70_000596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630546.1"
                     /translation="MIPELIISGEEANGEFLMVIPGKMLFCSFCVMLMKQVRKIASVE
                     "
     gene            52836..55397
                     /gene="mutS"
                     /locus_tag="IRB70_000597"
     CDS             52836..55397
                     /gene="mutS"
                     /locus_tag="IRB70_000597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBC0630547.1"
                     /translation="MSAIENFDAHTPMMQQYLKLKAQHPEILLFYRMGDFYELFYDDA
                     KRASQLLDISLTKRGASAGEPIPMAGIPYHAVENYLAKLVNQGESVAICEQIGDPATS
                     KGPVERKVVRIVTPGTISDEALLQERQDNLLAAIWQDSKGFGYATLDISSGRFRLSEP
                     ADRETMAAELQRTNPAELLYAEDFAEMSLIEGRRGLRRRPLWEFEIDTARQQLNLQFG
                     TRDLVGFGVENAPRGLCAAGCLLQYAKDTQRTTLPHIRSITMEREQDSIIMDAATRRN
                     LEITQNLAGGAENTLASVLDCTVTPMGSRMLKRWLHMPVRDTRVLLERQQTIGALQDF
                     TAELQPVLRQVGDLERILARLALRTARPRDLARMRHAFQQLPELRALLENVESAPVQA
                     LREKMGEFAELRDLLERAIIDTPPVLVRDGGVIAPGYNEELDEWRALADGATDYLERL
                     EIRERERTGLDTLKVGFNAVHGYYIQISRGQSHLAPINYMRRQTLKNAERYIIPELKE
                     YEDKVLTSKGKALALEKQLYEELFDLLLPHLEALQQSASALAELDVLVNLAERAYTLN
                     YTCPTFIDKPGIRITEGRHPVVEQVLNEPFIANPLNLSPQRRMLIITGPNMGGKSTYM
                     RQTALIALMAYIGSYVPAQKVEIGPIDRIFTRVGAADDLASGRSTFMVEMTETANILH
                     NATEYSLVLMDEIGRGTSTYDGLSLAWACAENLANKIKALTLFATHYFELTQLPEKME
                     GVANVHLDALEHGDTIAFMHSVQDGAASKSYGLAVAALAGVPKEVIKRARQKLRELES
                     ISPNAAATQVDGTQMSLLSAPEETSPAVEALENLDPDSLTPRQALEWIYRLKSLV"
     gene            55503..56159
                     /gene="pphB"
                     /locus_tag="IRB70_000598"
     CDS             55503..56159
                     /gene="pphB"
                     /locus_tag="IRB70_000598"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HBC0630548.1"
                     /translation="MPSTRYQKINAHHYRYIWAVGDIHGDYQLLQSRLHQLSFCPETD
                     LLISTGDNIDRGPKSLNVLHLLNQPWFTSVKGNHEAMALDAFETGDGNMWLASGGDWF
                     FDLNDSEQQAAIDLLLKFHHLPHIIEVTNDNTKYVITHADYPGNEYLFGKEIAESELL
                     WPVDRVQKSLNGELQQINGADYFIFGHMVFDNIQTFANQIYIDTGSPKSGRLSFYKIK
                     "
     gene            complement(56200..56436)
                     /locus_tag="IRB70_000599"
     CDS             complement(56200..56436)
                     /locus_tag="IRB70_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630549.1"
                     /translation="MICPRCADEQIEVMAKSPVKDVWTVYQCQHCLYTWRDTEPLRRT
                     SREHYPEAFRMTQKDIDDAPMVPSIPPLLAADKR"
     gene            complement(56447..57874)
                     /locus_tag="IRB70_000600"
     CDS             complement(56447..57874)
                     /locus_tag="IRB70_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBC0630550.1"
                     /translation="MAFDDLRSFLQALDDHGQLLKISEEVNAEPDLAAAANATGRIGD
                     GAPALWFDNIRGFTDARVAMNTIGSWQNHAISLGLPPNTPVKKQIDEFIRRWDNFPIA
                     PERRANPAWAQNTVDGDEINLFDILPLFRLNDGDGGFYLDKACVVSRDPLDPDNFGKQ
                     NVGIYRMEVKGKRKLGLQPVPMHDIALHLHKAEERGEDLPIAITLGNDPIITLMGATP
                     LKYDQSEYEMAGALRESPYPIATAPLTGFDVPWGSEVILEGVIESRKREIEGPFGEFT
                     GHYSGGRNMTVVRIDKVSYRSKPIFESLYLGMPWTEIDYLMGPATCVPLYQQLKAEFP
                     EVQAVNAMYTHGLLAIISTKKRYGGFARAVGLRAMTTPHGLGYVKMVIMVDEDVDPFN
                     LPQVMWALSSKVNPAGDLVQLPNMSVLELDPGSSPAGITDKLIIDATTPVAPDNRGHY
                     SQPVVDLPETKAWAEKLTAMLAARK"
     gene            complement(57874..58468)
                     /locus_tag="IRB70_000601"
                     /pseudo
     CDS             complement(57874..58468)
                     /locus_tag="IRB70_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311620.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
     gene            58615..59022
                     /locus_tag="IRB70_000602"
     CDS             58615..59022
                     /locus_tag="IRB70_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBC0630551.1"
                     /translation="MALRNKAFHQLRQLFQQHTARWQHELPDLTKPQYAVMRAIADKP
                     GIEQVALIEAAVSTKATLAEMLARMENRGLVRREHDAADKRRRFVWLTAEGEKVLAAA
                     IPIGDSVDEEFLGRLSGEEQELFMQLVRKMMSK"
     gene            complement(59143..60135)
                     /gene="rpoS"
                     /locus_tag="IRB70_000603"
     CDS             complement(59143..60135)
                     /gene="rpoS"
                     /locus_tag="IRB70_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000081498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoS"
                     /protein_id="HBC0630552.1"
                     /translation="MSQNTLKVHDLNEDAEFDENGVEVFDEKALVEEEPSDNDLAEEE
                     LLSQGATQRVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV
                     VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQTIERAIMN
                     QTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQLDKPVDDVSRMLRLNER
                     ITSVDTPLGGDSEKALLDILADEKENGPEDTTQDDDMKQSIVKWLFELNAKQREVLAR
                     RFGLLGYEAATLEDVGREIGLTRERVRQIQVEGLRRLREILQTQGLNIEALFRE"
     gene            complement(60198..61337)
                     /gene="nlpD"
                     /locus_tag="IRB70_000604"
     CDS             complement(60198..61337)
                     /gene="nlpD"
                     /locus_tag="IRB70_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator NlpD"
                     /protein_id="HBC0630553.1"
                     /translation="MSAGSPKFTVRRIAALSLVSLWLAGCSDTSNPPAPVSSVNGNAP
                     TNTNSGMLITPPSKMGTTSTAQQPQIQPVQQPQIQATQQPQIQPVQPVAQQPVQMENG
                     RIVYNRQYGNIPKGSYSGSTYTVKKGDTLFYIAWITGNDFRDLAQRNNIQAPYALNVG
                     QTLQVGNASGTPITGGNAITQADAAEQGVVIKPAQNSTVAVASQPTITYSESSGEQSA
                     NKMLPNNKPTATTVTAPVTVPTASTTEPTVSSTSTSTPISTWRWPTEGKVIETFGASE
                     GGNKGIDIAGSKGQAIIATADGRVVYAGNALRGYGNLIIIKHNDDYLSAYAHNDTMLV
                     REQQEVKAGQKIATMGSTGTSSTRLHFEIRYKGKSVNPLRYLPQR"
     gene            complement(61477..62103)
                     /gene="pcm"
                     /locus_tag="IRB70_000605"
     CDS             complement(61477..62103)
                     /gene="pcm"
                     /locus_tag="IRB70_000605"
                     /EC_number="2.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-L-isoaspartate O-methyltransferase"
                     /protein_id="HBC0630554.1"
                     /translation="MVSRRVQALLDQLRAQGIQDEQVLNALAAVPREKFVDEAFEQKA
                     WDNIALPIGQGQTISQPYMVARMTELLELTPQSRVLEIGTGSGYQTAILAHLVQHVCS
                     VERIKGLQWQARRRLKNLDLHNVSTRHGDGWQGWQARAPFDAIIVTAAPPEIPTALMT
                     QLDEGGILVLPVGEEHQYLKRVRRRGGEFIIDTVEAVRFVPLVKGELA"
     gene            complement(62097..62858)
                     /gene="surE"
                     /locus_tag="IRB70_000606"
     CDS             complement(62097..62858)
                     /gene="surE"
                     /locus_tag="IRB70_000606"
                     /EC_number="3.1.3.5"
                     /EC_number="3.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'/3'-nucleotidase SurE"
                     /protein_id="HBC0630555.1"
                     /translation="MRILLSNDDGVHAPGIQTLAKALREFADVQVVAPDRNRSGASNS
                     LTLESSLRTFTFENGDIAVQMGTPTDCVYLGVNALMRPRPDIVVSGINAGPNLGDDVI
                     YSGTVAAAMEGRHLGFPALAVSLDGHKHYDTAAAVTCSILRALCKEPLRTGRILNINV
                     PDLPLDQIKGIRVTRCGTRHPADQVIPQQDPRGNTLYWIGPPGGKCDAGPGTDFAAVD
                     EGYVSITPLHVDLTAHSAQDVVSDWLNSVGVGTQW"
     gene            complement(62839..63888)
                     /gene="truD"
                     /locus_tag="IRB70_000607"
     CDS             complement(62839..63888)
                     /gene="truD"
                     /locus_tag="IRB70_000607"
                     /EC_number="5.4.99.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(13) synthase TruD"
                     /protein_id="HBC0630556.1"
                     /translation="MIEFDNLTYLHGKPQGTGLLKANPEDFVVVEDLGFEPDGEGEHI
                     LVRILKNGCNTRFVADALAKFLKIHSREVSFAGQKDKHAVTEQWLCARVPGKEMPDLS
                     AFQLEGCQVLEYARHKRKLRLGALKGNAFTLVLREVSNRDDVEQRLIDICVKGVPNYF
                     GAQRFGIGGSNLQGALRWAQTNTPVRDRNKRSFWLSAARSALFNQIVAERLKKADVNQ
                     VVDGDALQLAGRGSWFVATTEELVELQRRVNDKELMITAALPGSGEWGTQREALAFEQ
                     AAVAAETELQALLVREKVEAARRAMLLYPQQLSWNWWDDVTVEIRFWLPAGSFATSVV
                     RELINTTGDYAHIAE"
     gene            complement(63885..64364)
                     /gene="ispF"
                     /locus_tag="IRB70_000608"
     CDS             complement(63885..64364)
                     /gene="ispF"
                     /locus_tag="IRB70_000608"
                     /EC_number="4.6.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 2,4-cyclodiphosphate
                     synthase"
                     /protein_id="HBC0630557.1"
                     /translation="MRIGHGFDVHAFGGEGPIIIGGVRIPYEKGLLAHSDGDVALHAL
                     TDALLGAAALGDIGKLFPDTDPAFKGADSRELLREAWRRIQAKGYTLGNVDVTIIAQA
                     PKMLPHIPQMRVFIAEDLGCHMDDVNVKATTTEKLGFTGRGEGIACEAVALLIKATK"
     gene            complement(64364..65074)
                     /gene="ispD"
                     /locus_tag="IRB70_000609"
     CDS             complement(64364..65074)
                     /gene="ispD"
                     /locus_tag="IRB70_000609"
                     /EC_number="2.7.7.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-C-methyl-D-erythritol 4-phosphate
                     cytidylyltransferase"
                     /protein_id="HBC0630558.1"
                     /translation="MATTHLDVCAVVPAAGFGRRMQTECPKQYLSIGNQTILEHSVHA
                     LLAHPRVKHVVIAISPGDSRFAQLPLANHPQITVVDGGDERADSVLAGLKAAGDAQWV
                     LVHDAARPCLHQDDLARLLALSETSRTGGILAAPVRDTMKRAEPGKNAIAHTVDRNGL
                     WHALTPQFFPRELLHDCLTRALNEGATITDEASALEYCGFHPQLVEGRADNIKVTRPE
                     DLALAEFYLTRTIHQENT"
     gene            complement(65093..65404)
                     /gene="ftsB"
                     /locus_tag="IRB70_000610"
     CDS             complement(65093..65404)
                     /gene="ftsB"
                     /locus_tag="IRB70_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsB"
                     /protein_id="HBC0630559.1"
                     /translation="MGKLTLLLLAILVWLQYSLWFGKNGIHDYTRVNDDVAAQQATNA
                     KLKARNDQLFAEIDDLNGGQEALEERARNELSMTRPGETFYRLVPDASKRAQSAGQNN
                     R"
     gene            complement(65598..65921)
                     /locus_tag="IRB70_000611"
     CDS             complement(65598..65921)
                     /locus_tag="IRB70_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3561 family protein"
                     /protein_id="HBC0630560.1"
                     /translation="MRNSHNITLTNNDSLTEDEETTWSLPGAVVGFISWLFALAMPML
                     IYGSNTLFFFIYTWPFFLALMPVAVVVGIALHSLMDGKLRYSIVFTLVTVGIMFGALF
                     MWLLG"
     gene            complement(65971..66576)
                     /gene="cysC"
                     /locus_tag="IRB70_000612"
     CDS             complement(65971..66576)
                     /gene="cysC"
                     /locus_tag="IRB70_000612"
                     /EC_number="2.7.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylyl-sulfate kinase"
                     /protein_id="HBC0630561.1"
                     /translation="MALHDENVVWHSHPVTVQQRELHHGHRGVVLWFTGLSGSGKSTV
                     AGALEEALHKLGVSTYLLDGDNVRHGLCSDLGFSDADRKENIRRVGEVANLMVEAGLV
                     VLTAFISPHRAERQMVRERVGEGRFIEVFVDTPLAICEARDPKGLYKKARAGELRNFT
                     GIDSVYEAPESAEIHLNGEQLVTNLVQQLLDLLRQNDIIRS"
     gene            complement(66576..68003)
                     /gene="cysN"
                     /locus_tag="IRB70_000613"
     CDS             complement(66576..68003)
                     /gene="cysN"
                     /locus_tag="IRB70_000613"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysN"
                     /protein_id="HBC0630562.1"
                     /translation="MNTALAQQIANEGGVEAWMIAQQHKSLLRFLTCGSVDDGKSTLI
                     GRLLHDTRQIYEDQLSSLHNDSKRHGTQGEKLDLALLVDGLQAEREQGITIDVAYRYF
                     STEKRKFIIADTPGHEQYTRNMATGASTCELAILLIDARKGVLDQTRRHSFISTLLGI
                     KHLVVAINKMDLVDYSEETFTRIREDYLTFAGQLPGNLDIRFVPLSALEGDNVASQSE
                     SMPWYSGPTLLEVLETVEIQRVVDAQPMRFPVQYVNRPNLDFRGYAGTLASGRVEVGQ
                     RVKVLPSGVESNVARIVTFDGDREEAFAGEAITLVLTDEIDISRGDLLLAADEALPAV
                     QSASVDVVWMAEQPLSPGQSYDIKIAGKKTRARVDGIRYQVDINNLTQREVENLPLNG
                     IGLVDLTFDEPLVLDRYQQNPVTGGLILIDRLSNVTVGAGMVHEPVSQATAAPSQFSV
                     FELELNALVRRHFPHWGARDLLGDK"
     gene            complement(68005..68913)
                     /gene="cysD"
                     /locus_tag="IRB70_000614"
     CDS             complement(68005..68913)
                     /gene="cysD"
                     /locus_tag="IRB70_000614"
                     /EC_number="2.7.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate adenylyltransferase subunit CysD"
                     /protein_id="HBC0630563.1"
                     /translation="MDQKRLTHLRQLEAESIHIIREVAAEFSNPVMLYSIGKDSSVML
                     HLARKAFYPGTLPFPLLHVDTGWKFREMYEFRDRTAKAYGCELLVHKNPEGVAMGINP
                     FVHGSAKHTDIMKTEGLKQALNKYGFDAAFGGARRDEEKSRAKERIYSFRDRFHRWDP
                     KNQRPELWHNYNGQINKGESIRVFPLSNWTEQDIWQYIWLENIDIVPLYLAAERPVLE
                     RDGMLMMIDDNRIDLQPGEVIKKRMVRFRTLGCWPLTGAVESNAQTLPEIIEEMLVST
                     TSERQGRVIDRDQAGSMELKKRQGYF"
     gene            69165..70202
                     /gene="iap"
                     /locus_tag="IRB70_000615"
     CDS             69165..70202
                     /gene="iap"
                     /locus_tag="IRB70_000615"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase isozyme conversion
                     aminopeptidase"
                     /protein_id="HBC0630564.1"
                     /translation="MFSALRHRTAALALGVCFILPVHASSPKPGDFANTQARHIATFF
                     PGRMTGTPAEMLSADYIRQQFQQMGYRSDIRTFNSRYIYTARDNRKSWHNVTGSTVIA
                     AHEGKAPQQIIIMAHLDTYAPLSDADADANLGGLTLQGMDDNAAGLGVMLELAERLKN
                     TPTEYGIRFVATSGEEEGKLGAENLLKRMSDTEKKNTLLVINLDNLIVGDKLYFNSGV
                     KTPEAVRKLTRDRALAIARSHGIAATTNPGLNKNYPKGTGCCNDAEVFDKAGIAVLSV
                     EATNWNLGNKDGYQQRSKTPAFPAGNSWHDVRLDNQQHIDKALPGRIERRCRDVMRII
                     LPLVKKLAKAS"
     repeat_region   70223..71106
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=70284..70312
                     /rpt_unit_seq="cggtttatccccgctggcgcggggaactc"
     gene            complement(71212..71496)
                     /gene="cas2"
                     /locus_tag="IRB70_000616"
     CDS             complement(71212..71496)
                     /gene="cas2"
                     /locus_tag="IRB70_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endoribonuclease
                     Cas2"
                     /protein_id="HBC0630565.1"
                     /translation="MSMLVVVTENVPPRLRGRLAIWLLEVRAGVYVGDVSARIREMIW
                     EQISGLAEEGNVVMAWATNTESGFEFQTFGVNRRTPVDLDGLRLVSFLPV"
     gene            complement(71498..72415)
                     /gene="cas1e"
                     /locus_tag="IRB70_000617"
     CDS             complement(71498..72415)
                     /gene="cas1e"
                     /locus_tag="IRB70_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated endonuclease Cas1"
                     /protein_id="HBC0630566.1"
                     /translation="MTWLPLNPIPLKDRVSMIFLQYGQIDVIDGAFVLIDKTGIRTHI
                     PVGSVACIMLEPGTRVSHAAVRLAAQVGTLLVWVGEAGVRVYASGQPGGARSDKLLYQ
                     AKLALDEDLRLKVVRKMFELRFGEPAPARRSVEQLRGIEGSRVRATYVLLAKQYGVKW
                     NGRRYDPKDWEKGDTVNQCISAATSCLYGVTEAAILAAGYAPAIGFVHTGKPLSFVYD
                     IADIIKFDTVVPKAFEIARRNPGEPDREVRLACRDIFRSSKTLAKLIPLIEDVLAAGE
                     IQPPAPPEDAQPVAIPLPVSLGDAGHRSS"
     gene            complement(72431..73030)
                     /gene="cas6e"
                     /locus_tag="IRB70_000618"
     CDS             complement(72431..73030)
                     /gene="cas6e"
                     /locus_tag="IRB70_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas6/Cse3/CasE"
                     /protein_id="HBC0630567.1"
                     /translation="MYLSKVIIARAWSRDLYQLHQGLWHLFPNRPDAARDFLFHVEKR
                     NTPEGCHVLLQSAQMPVSTAVATVIKTKQVEFQLQVGVPLYFRLRANPIKTILDNQKR
                     LDSKGNIKRCRVPLIKEAEQIAWLQRKLGNAARVEDVHPISERPQYFSGDGKSGKIQT
                     VCFEGVITINDAPALIDLVQQGIGPAKSMGCGLLSLAPL"
     gene            complement(73017..73691)
                     /gene="cas5e"
                     /locus_tag="IRB70_000619"
     CDS             complement(73017..73691)
                     /gene="cas5e"
                     /locus_tag="IRB70_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417237.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cas5/CasD"
                     /protein_id="HBC0630568.1"
                     /translation="MRSYLILRLAGPMQAWGQPTFEGTRPTGRFPTRSGLLGLLGACL
                     GIQRDDTSSLQALSESVQFAVRCDELILDDRRVSVTGLRDYHTVLGAREDYRGLKSHE
                     TIQTWREYLCDASFTVALWLTPHATMVISELEKAVLKPRYTPYLGRRSCPLTHPLFLG
                     TCKASDPQKALLNYEPVGGDIYSEESVTGHYLKFTARDEPMITLPRQFASREWYVIKG
                     GMDVSQ"
     gene            complement(73694..74785)
                     /gene="cas7e"
                     /locus_tag="IRB70_000620"
     CDS             complement(73694..74785)
                     /gene="cas7e"
                     /locus_tag="IRB70_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein
                     Cas7/Cse4/CasC"
                     /protein_id="HBC0630569.1"
                     /translation="MSNFINIHVLISHSPSCLNRDDMNMQKDAIFGGKRRVRISSQSL
                     KRAMRKSDYYAQNIGESSLRTIHLAQLRDVLRQKLGERFDQKIIDKTLALLSGKLVDE
                     AEKISADAVTPWVVGEIAWFCEQVAKAEADNLDDKKLLKVLKEDIAAIRVNLQQGVDI
                     ALSGRMATSGMMSELGKVDGAMSIAHAITTHQVDSDIDWFTAVDDLQEQGSAHLGTQE
                     FSSGVFYRYANINLAQLQENLGGASREQALEIATHVVHMLATEVPGAKQRTYAAFNPA
                     DMVMVNFSDMPLSMANAFEKAVKAKDGFLQPSIQAFNQYWDRVANGYGLNGAAAQFSL
                     SDVDPITAQVKQMPTLEQLKSWVRNNGEA"
     gene            complement(74798..75280)
                     /gene="casB"
                     /locus_tag="IRB70_000621"
     CDS             complement(74798..75280)
                     /gene="casB"
                     /locus_tag="IRB70_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse2/CasB"
                     /protein_id="HBC0630570.1"
                     /translation="MADEIDAMALYRAWQQLDNGACAQIRRVSEPDELRDIPAFYRLV
                     QPFGWENPRHQQALLRMVFCLSAGKNVIRHQDKKPEQTTGISLGRALANSGRINERRI
                     FQLIRSDRTADMVQLRRLLTHAEPVLDWPLMARMLTWWGKRERQQLLEDFVLTTNKNA
                     "
     gene            complement(75273..76781)
                     /gene="casA"
                     /locus_tag="IRB70_000622"
     CDS             complement(75273..76781)
                     /gene="casA"
                     /locus_tag="IRB70_000622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I-E CRISPR-associated protein Cse1/CasA"
                     /protein_id="HBC0630571.1"
                     /translation="MNLLIDNWIPVRPRNGGEVQIINLQSLYCSRDQWRLSLPRDDME
                     LAALALLVCIGQIIAPAKDDVEFRHRIMNPLTEDEFQQLIAPWIDMFYLNHAEHPFMQ
                     TKGVKANDVTPMEKLLAGVSGATNCAFVNQPGQGEALCGGCTAIALFNQANQAPGFGG
                     GFKSGLRGGTPITTFVCGIDLRSTVLLNVLTIPRLQKQFPNELHTENQPTWVKPVKPN
                     ESVPASSIGFVRGLFWQPAHIELCDPIGIGKCSCCGQESNLRYTGFLKEKFTFTVNGL
                     WPHPHSPCLVTVKKGEVEEKFLAFTTSAPSWTQISRVVVDKIIQNENGNRVAAVVNQF
                     RNIAPQSPLELIMGGYRNNQASILERRHDVLMFNQGWQQYGNVINEIVTVGLGYKTAL
                     RKALYTFAEGFKNKDFKGAGVSVHETAERHFYRQSELLIPDVLANINFSQADEVIADL
                     RDKLHQLCEMLFNQSEAPYAHHPKLISTLALARATLYKHLRELKPQGGPSNG"
     gene            complement(77196..79862)
                     /gene="cas3"
                     /locus_tag="IRB70_000623"
     CDS             complement(77196..79862)
                     /gene="cas3"
                     /locus_tag="IRB70_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRISPR-associated helicase/endonuclease Cas3"
                     /protein_id="HBC0630572.1"
                     /translation="MEPFKYICHYWGKSSKSLTKGNDIHLLIYHCLDVAAVADCWWEQ
                     SVVLQNAFCQNEMLSKQMVKAWLLFFIALHDIGKFDIRFQYKSAESWLKLNPATPSLN
                     GPSTQMCRKFNHGAAGLYWFNQDSLSEQSPGDFFSFFDAAPHPYESWFPWVEAVTGHH
                     GFILHSQDQDKSRWEMPASLASYAAQDKQAREEWISVLEALFLTPAGLSINDIPPDCS
                     SLLAGFCSLADWLGSWTTTNTFLFKEDAPSNINALRTYFQDRQQDASRVLELSGLVSN
                     KRCYEGVHALLDNGYQPRQLQVLVDALPAAPGLTVIEAPTGSGKTETALAYAWKLIDQ
                     QLADSVIFALPTQATANAMLSRMEANASRLFTSPNLILAHGNSRFNHLFQSIKSRAFT
                     EQGQEEAWVQCCQWLSQSNKKVFLGQIGVCTIDQVLISVLPVKHRFIRGLGIGRSVLI
                     VDEVHAYDTYMNGLLEAVLKAQADVGGSVILLSATLPMKQKQKLLDTYGLHTDPEENN
                     SAYPLINWRGVNGAQRFDLLAHSEQLPPRFSIRPEPIYLADMLPDLRMLERMIVAANA
                     GAQVCLICNLVDVAQLCHQRLKELNNTQVDIDLFHARFTLNDRREKENRVISNFGKNG
                     KRNVGRILVATQVVEQSLDVDFDWLITQHCPADLLFQRLGRLHRHHRKYRPAGFEVPL
                     ASVLLPDGEGYGRHEHIYSNVRVMWRTQQHIEELNGASLFFPDAYRQWLDSIYDDAEM
                     DEPEWVIKGMDKYESAECEKRFKARKVLQWAEEYSLQDNDETILAVTRDGEMSLPLLP
                     YLQTSSGKQLLDGQVYEDLSHEQQYEALALNRVNVPFTWKRNFSEVVDEDGVLWLEGK
                     QNQDGWIWQGNNIVITYTRDEGMTRVIPANPK"
     gene            complement(80221..80955)
                     /gene="cysH"
                     /locus_tag="IRB70_000624"
     CDS             complement(80221..80955)
                     /gene="cysH"
                     /locus_tag="IRB70_000624"
                     /EC_number="1.8.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HBC0630573.1"
                     /translation="MSKLDLNALNELPKVDRILALAETNAELEKLDAEGRVAWALDNL
                     PGEYVLSSSFGIQAAVSLHLVNQIHPDIPVILTDTGYLFPETYRFIDELTDKLKLNLK
                     VYRATESAAWQEARYGKLWEQGVEGIEKYNDINKVEPMNRALKELNAQTWFAGLRREQ
                     SGSRANLPVLAIQRGVFKVLPIIDWNNRTIYQYLQKHGLKYHPLWDEGYLSVGDTHTT
                     RKWEPGMAEEETRFFGLKRECGLHEG"
     gene            complement(81029..82741)
                     /gene="cysI"
                     /locus_tag="IRB70_000625"
     CDS             complement(81029..82741)
                     /gene="cysI"
                     /locus_tag="IRB70_000625"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001290736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="assimilatory sulfite reductase (NADPH)
                     hemoprotein subunit"
                     /protein_id="HBC0630574.1"
                     /translation="MSEKHPGPLVVEGKLTDAERMKLESNYLRGTIAEDLNDGLTGGF
                     KGDNFLLIRFHGMYQQDDRDIRAERAEQKLEPRHAMLLRCRLPGGVITTKQWQAIDKF
                     AGENTIYGSIRLTNRQTFQFHGILKKNVKPVHQMLHSVGLDALATANDMNRNVLCTSN
                     PYESQLHAEAYEWAKKISEHLLPRTRAYAEIWLDQEKVATTDEEPILGQTYLPRKFKT
                     TVVIPPQNDIDLHANDMNFVAIAENGKLVGFNLLVGGGLSIEHGNKKTYARTASEFGY
                     LPLEHTLAVAEAVVTTQRDWGNRTDRKNAKTKYTLERVGVETFKAEVERRAGIKFEPI
                     RPYEFTGRGDRIGWVKGIDDNWHLTLFIENGRILDYPGRPLKTGLLEIAKIHKGDFRI
                     TANQNLIIAGVPESEKAKIEKIAKESGLMNAVTPQRENSMACVSFPTCPLAMAEAERF
                     LPSFIDNIDNLMAKHGVSDEHIVMRVTGCPNGCGRAMLAEVGLVGKAPGRYNLHLGGN
                     RIGTRIPRMYKENITEPEILASLDELIGRWAKEREAGEGFGDFTVRAGIIRPVLDPAR
                     DLWD"
     gene            complement(82741..84540)
                     /gene="cysJ"
                     /locus_tag="IRB70_000626"
     CDS             complement(82741..84540)
                     /gene="cysJ"
                     /locus_tag="IRB70_000626"
                     /EC_number="1.8.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent assimilatory sulfite reductase
                     flavoprotein subunit"
                     /protein_id="HBC0630575.1"
                     /translation="MTTQVPPSALLPLNPEQLARLQAATTDLTPTQLAWVSGYFWGVL
                     NQQPAALAATPAPAAEMPGITIISASQTGNARRVAEALRDDLLAAKLNVKLVNAGDYK
                     FKQIASEKLLIVVTSTQGEGEPPEEAVALHKFLFSKKAPKLENTAFAVFSLGDSSYEF
                     FCQSGKDFDSKLAEQGGERLLDRVDADVEYQAAASEWRARVVDALKSRAPVAAPSQSV
                     ATGAVNEIHTSPYSKDAPLVASLSVNQKITGRNSEKDVRHIEIDLGDSGLRYQPGDAL
                     GVWYQNDPALVKELVELLWLKGDEPVTVEGKTLPLNEALQWHFELTVNTANIVENYAT
                     LTRSESLLPLVGDKAKLQHYAATTPIVDMVRFAPAQLDAEALVGLLRPLTPRLYSIAS
                     SQAEVESEVHVTVGVVRYDIEGRARAGGASSFLADRVEEEGEVRVFIEHNDNFRLPAN
                     PETPVIMIGPGTGIAPFRAFMQQRAADEAPGKNWLFFGNPHFTEDFLYQVEWQRYVKE
                     GVLTRIDLAWSRDQKEKVYVQDKLREQGAELWRWINDGAHIYVCGDANRMAKDVEQAL
                     LEVIAEFGGMDTEAADEFLSELRVERRYQRDVY"
     gene            84859..85221
                     /gene="queD"
                     /locus_tag="IRB70_000627"
     CDS             84859..85221
                     /gene="queD"
                     /locus_tag="IRB70_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708563.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-carboxytetrahydropterin synthase QueD"
                     /protein_id="HBC0630576.1"
                     /translation="MSTTLFKDFTFEAAHRLPHVPQGHKCGRLHGHSFMVRLEITGEV
                     DPHTGWIIDFAELKAAFKPTYERLDHHYLNDIPGLENPTSEVLAKWIWDQVKPVVPLL
                     SAVMVKETCTAGCIYRGE"
     gene            85299..86570
                     /locus_tag="IRB70_000628"
     CDS             85299..86570
                     /locus_tag="IRB70_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417246.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBC0630577.1"
                     /translation="MEDDCDIIIIGAGIAGTACALRCARAGLSVLLLERAEIPGSKNL
                     SGGRLYTQALAELLPQFHLTAPLERRITHESLSLLTPDGATTFSSLQPGGESWSVLRA
                     RFDPWLVAEAEKEGVECIPGATVDALYEENGRVCGVICGDDILRACYVVLAEGANSVL
                     AERHGLVTRPAGEAMALGIKEVLSLETSAIEERFHLENNEGAALLFSGGICDDLPGGA
                     FLYTNQQTLSLGIVCPLSSLTQSRVPASELLARFKTHPAVRPLIKNTESLEYGAHLVP
                     EGGLHSMPVQYAGNGWLLLGDALRSCVNTGISVRGMDMALTGAQAAAQTLISACQHRE
                     PQNLFALYHHNVERSLLWDVLQRYQHVPALLQRPGWYRAWPALMQDISRDLWDQGDKP
                     VPPLRQLFWRHLRRHGLWHLAGDVIRSLRCL"
     gene            86561..86821
                     /locus_tag="IRB70_000629"
     CDS             86561..86821
                     /locus_tag="IRB70_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417247.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HBC0630578.1"
                     /translation="MSVARNLWRVADAPHIVPADSVERQTVQWLINACPAGLFSLTPE
                     GDLRIDYRSCLECGTCRLLCDEKTLQQWRYPPSGFGITYRFG"
     gene            86838..87413
                     /locus_tag="IRB70_000630"
     CDS             86838..87413
                     /locus_tag="IRB70_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate responsive antiterminator"
                     /protein_id="HBC0630579.1"
                     /translation="MPLLHLLRQNPVIAAVKDNASLQLAIDSECQFISVLYGNICTIS
                     HIVKKIKSAGKYAFIHVDLLEGASNKEVVIQFLKLVTEADGIISTKASMLKAARAEGF
                     FCIHRLFIVDSISFHNIDKQVAQSNPDCIEILPGCMPKVLGWVTEKIRQPLIAGGLVC
                     DEEDARNAINAGVVALSTTNTGVWTLAKKLL"
     gene            complement(87560..88420)
                     /locus_tag="IRB70_000631"
     CDS             complement(87560..88420)
                     /locus_tag="IRB70_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417249.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBC0630580.1"
                     /translation="MNIAIVTINQENAAIASWLAAQDFSGCTLAHWQIEPQPVVAEQV
                     LDALVEQWQRTPADVVLFPPGTFGDELSTRLAWRLHGASICQVTSLDIPTVSVRKSHW
                     GNALTATLQTDKRPLCLSLARQAGADKNATLPSGMQQLNIVPGALPDWLVSLENLKNV
                     TRDPLAEARRVLVVGQGGEADNQEIAMLAEKLGAEVGYSRARVMNGGVDAEKVIGISG
                     HLLAPEVCIVVGASGAAALMAGVCNSKFVVAINHDASAAVFSQADVGVVDDWKVVLEA
                     MVTNIHADCQ"
     gene            complement(88417..89196)
                     /locus_tag="IRB70_000632"
     CDS             complement(88417..89196)
                     /locus_tag="IRB70_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708567.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit beta/FixA
                     family protein"
                     /protein_id="HBC0630581.1"
                     /translation="MNILLAFKAEPDAGMLAEKEWQAAAQGNIGPDVSLLRSLLGADE
                     QAAAALLLAQRKNGTPMSLTALSMGDERALHWLRYLMALGFEDAVLLETVADLRFAPE
                     FVARHIAEWQRQNPLDLIITGCQSSEGQNGQTPFLLAEMLGWPCFTQVERFTLDAPFI
                     TLEQRTENGLRCCRVRLPAVIAVRQCGEVALPVPGMRQRMAAGKAAIIRKTVAVELPA
                     MQCLHLARAEQRRGATLIDGQTVAEKAQKLWQNYLRQRMQP"
     gene            complement(89174..90583)
                     /locus_tag="IRB70_000633"
     CDS             complement(89174..90583)
                     /locus_tag="IRB70_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630582.1"
                     /translation="MTGRCLFGFSGEKPFLLPDNEGVKMNTSPVRMDDLPLNRFHCRI
                     AALTFGAHLTDGYVLGVIGYAIIQLTPAMQLTPFMAGMIGGSALLGLFLGSLVLGWIS
                     DHIGRQKIFTFSFLLITLASFLQFFATTPEHLIGLRILIGIGLGGDYSVGHTLLAEFS
                     PRRHRGILLGAFSVVWTVGYVLASIAGHHFISENPEAWRWLLASAALPALLITLLRWG
                     TPESPRWLLRQGRFAEAHAIVHRYLGPHVLLGDEVAAATHKHIKTLFSSRYWRRTAFN
                     SVFFVCLVIPWFVIYTWLPTIAQTIGLEDALTASLMLNALLIVGALLGLVLTHLLAHR
                     KFLLGSFLLLAATLVVMACLPSGSSLTLLLFVLFSTTISAVSNLVGILPAESFPTDIR
                     SLGVGFATAMSRLGAAVSTGLLPWVLAQWGMQATLLLLAAVLLVGFVVTWLWAPETKA
                     LPLVAAGNVGGANEHSVSV"
     gene            complement(90605..92059)
                     /locus_tag="IRB70_000634"
     CDS             complement(90605..92059)
                     /locus_tag="IRB70_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBC0630583.1"
                     /translation="MSLSRAAIVDQLKEIVGADRVITDETVLKKNSIDRFRKFPDIHG
                     IYTLPIPAAVVKLGSTEQVSRVLNFMNAHKINGVPRTGASATEGGLETVVENSVVLDG
                     SAMNQIINIDIENMQATAQCGVPLEVLENALREKGYTTGHSPQSKPLAQMGGLVATRS
                     IGQFSTLYGAIEDMVVGLEAVLADGTVTRIKNVPRRAAGPDIRHIIIGNEGALCYITE
                     VTVKIFKFTPENNLFYGYILEDMKTGFNILREIMVEGYRPSIARLYDVEDGTQHFTHF
                     ADGKCVLIFMAEGNPRIAKATGEGIAEIVARYPQCQRVDSKLIETWFNHLNWGPDKVA
                     AERVQILKTGNMGFTTEVSGCWSCIHEIYESVINRIRTEFPHADDITMLGGHSSHSYQ
                     NGTNMYFVYDYNVVDCKPEEEIDKYHNPLNKIICEETIRLGGSMVHHHGIGKHRVHWS
                     KLEHGSAWTLLEGLKKQFDPNGIMNTGTIYPIEK"
     gene            complement(92129..92914)
                     /locus_tag="IRB70_000635"
     CDS             complement(92129..92914)
                     /locus_tag="IRB70_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBC0630584.1"
                     /translation="MSIESLNAFSMDFFSLKGKTAIVTGGNSGLGQAFAMALAKAGAN
                     VFIPSFVKDNGETKEMIEKQGVEVDFMQVDITAEGAPQKIIAACCERFGTVDILVNNA
                     GICKLNKVLDFGRADWDPMIDVNLTAAFELSYEAAKIMIPQKSGKIINICSLFSYLGG
                     QWSPAYSATKHALAGFTKAYCDELGQYNIQVNGIAPGYYATDITLATRSNPETNQRVL
                     DHIPANRWGDTQDLMGAAVFLASPASNYVNGHLLVVDGGYLVR"
     gene            93233..94510
                     /locus_tag="IRB70_000636"
     CDS             93233..94510
                     /locus_tag="IRB70_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630585.1"
                     /translation="MQHNSYRRWITLAIISFSGGVSFDLAYLRYIYQIPMAKFMGFSN
                     TEIGLIMSTFGIAAIILYAPSGVIADKFSHRKMITSAMIITGLLGLLMATYPPLWVML
                     CIQVAFAITTILMLWSVSIKAASLLGDHSEQGKIMGWMEGLRGVGVMSLAVFTMWVFS
                     RFAPDDSASLKTVIIIYSVVYILLGILCWFFVSDNNNLRSANNEEKQSFQLSDILAVL
                     RISTTWYCSMVIFGVFTIYAILSYSTNYLTEMYGMSLVAASYMGIVINKIFRALCGPL
                     GGIITTYSKVKSPTRVIQILSIIGLLALTALLVTNSNPQSVAMGIGLILLLGFTCYAS
                     RGLYWACPGEARTPSYIMGTTVGICSVIGFLPDVFVYPIIGHWQDTLPAAEAYRNMWL
                     MGMAALAMVIIFTFLLFQKIRTADSAPAMASSK"
     gene            94537..96015
                     /locus_tag="IRB70_000637"
     CDS             94537..96015
                     /locus_tag="IRB70_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBC0630586.1"
                     /translation="MSKKYIIGIDGGSQSTKVVMYDLEGNVVCEGKGLLQPMHTPDAD
                     TAEHPDDDLWASLCFAGHDLMSQFAGNKEDIVGIGLGSIRCCRALLKADGTPAAPLIS
                     WQDARVTRPYEHTNPDVAYVTSFSGYLTHRLTGEFKDNIANYFGQWPVDYKTWAWSED
                     AAVMEKFNIPRHMLFDVQMPGTVLGHITPQAALATHFPAGLPVVCTTSDKPVEALGAG
                     LLDDETAVISLGTYIALMMNGKALPKDPVAYWPIMSSIPQTLLYEGYGIRKGMWTVSW
                     LRDMLGESLIQDAKAQDLSPEDLLNKKASCVPPGCNGLMTVLDWLTNPWEPYKRGIMI
                     GFDSSMDYAWIYRSILESVALTLKNNYDNMCNEMNHFAKHVIITGGGSNSDLFMQIFA
                     DVFNLPARRNAINGCASLGAAINTAVGLGLYPDYATAVDKMVRVKDIFMPVESNAKRY
                     DAMNKGIFKDLTKHTDVILKKSYEVMHGELGNEDSIQSWSNA"
BASE COUNT        23045 a        25823 c        24387 g        23140 t
ORIGIN      
        1 aaaatcttta taaaatattt ggtgagcatc cacagcgagc tttcaaatat atcgaacaag
       61 gactttcaaa agaacaaatt ctggaaaaaa ctgggctatc gcttggcgta aaagacgcca
      121 gtctggccat tgaagaaggc gagatatttg tcatcatggg attatccggt tcgggtaaat
      181 ccacaatggt acgccttctc aatcgcctga ttgaacccac ccgcgggcaa gtgctgattg
      241 atggtgtgga tattgccaaa atatccgacg ccgaactccg tgaggtgcgc agaaaaaaga
      301 ttgcgatggt cttccagtcc tttgccttaa tgccgcatat gaccgtgctg gacaatactg
      361 cgttcggtat ggaattggcc ggaattaatg ccgaagaacg ccgggaaaaa gcccttgatg
      421 cactgcgtca ggtcgggcta gaaaattatg cccacagcta cccggatgaa ctctctggcg
      481 ggatgcgtca acgtgtggga ttagcccgcg cgttagcgat taatccggat atattattaa
      541 tggacgaagc cttctcggcg ctcgatccat taattcgcac tgagatgcag gatgagctgg
      601 taaaattaca ggcgaaacat cagcgcacca ttgtctttat ttctcacgat ctcgacgaag
      661 ctatgcgtat tggtgaccga attgccatta tgcaaaatgg tgaagtggtg caggttggta
      721 caccggatga aattcttaat aatccggcga atgattatgt ccgtaccttc ttccgtggcg
      781 tcgatattag tcaggtattc agtgcgaaag atattgctcg ccggacaccg aacggcttaa
      841 ttcgtaaaac ccccggcttc ggcccgcgtt cggcactgaa attattgcag gatgaagatc
      901 gcgaatatgg ctacgtcatc gaacgtggta ataagtttgt cggcgcagtg tctatcgatt
      961 cgcttaaaac cgcgttaacg cagcagcaag gtcttgatgc ggcgctgatt gatgcgccgt
     1021 tagcggtcga tgcacaaacg cctcttagcg agttgctctc tcatgtcgga caggcaccct
     1081 gtgcggtgcc cgtggtcgac gaggaccaac agtatgtcgg catcatttcg aaaggaatgc
     1141 tgctgcgcgc tttagatcgt gagggggtaa ataatggctg atcaaaataa tccgtgggat
     1201 accacgccag cggcggacag tgctgcacaa tccgcagacg cctggggtac accggctgct
     1261 gcaccgactg acggcggtgg tgctgactgg ctgaccagta cgcctgcgcc aaacgtcgag
     1321 cattttaata ttctcgatcc gttccataaa actctgatcc cgctcgacag ttgggtcact
     1381 gaagggatcg actgggtcgt tacccatttc cgtcccgtct tccagggcgt gcgcgttccg
     1441 gttgattata tcctcaacgg tttccagcaa ttgctgctgg gtatgcccgc gccggtggcg
     1501 attatcgttt tcgctctcat cgcctggcag atttccgggg tcggaatggg cgtggcgacg
     1561 ctggtttcgc tgattgccat cggcgcaatc ggtgcctggt cgcaggccat ggttaccctg
     1621 gcgctggtgt taaccgccct gctgttctgt atcgtcatag gtttgccgtt ggggatctgg
     1681 ctggcgagaa gtccgcgagc ggcgaaaatt attcgtccac tgcttgatgc catgcagacc
     1741 acgcccgcgt ttgtttatct ggtgccaatc gtcatgctgt ttggtatcgg caacgtgccg
     1801 ggcgtggtgg tgacgatcat ctttgcgctg ccgccgatta tccgtctgac gattctggga
     1861 attaaccagg ttccggcgga tctgattgaa gcctcgcgct cattcggtgc cagcccgcgc
     1921 cagatgctgt tcaaagttca gttaccgctg gcgatgccaa ccattatggc gggcgttaac
     1981 cagacgctga tgctggccct ttctatggtg gtcatcgcct cgatgattgc cgtcggcggg
     2041 ctgggtcaga tggtacttcg cggtatcggt cgtctggata tggggcttgc caccgttggc
     2101 ggcgtcggga ttgtgatcct cgccattatc ctcgaccgcc tgacgcaggc cgttgggcgc
     2161 gactcacgca gtcgcggcaa ccgtagatgg tacaccactg gccctgttgg tctgctgacc
     2221 cgcccattca ttaagtaact ctgcacttgc ccggtaacgc cgggcatatc accctgccaa
     2281 aaaaaggaat aacaatgcga catagcgtac tttttgcgac agcgtttgcc acgcttatct
     2341 ctacacaaac ttttgctgcc gacctgccgg gcaaaggcat tactgttaat ccggttcaga
     2401 gcaccatcac cgaagaaact ttccagacgc tgctggtcag ccgcgcgctg gagaaattag
     2461 gttataccgt caataaaccc agcgaagtgg attacaacgt tggctacacc tcgcttgctt
     2521 ccggcgatgc aaccttcacc gcagtgaact ggacgccact gcatgacaac atgtacgaag
     2581 ctgccggtgg cgataagaaa ttttatcgtg aaggagtatt tgttaacggc gcggcacagg
     2641 gttacctgat cgataagaaa accgccgacc agtataaaat taccaacatc gcgcaactta
     2701 aagatccgaa gatcgccaaa ctgttcgata ccaacggcga cggtaaagcg gatttaaccg
     2761 gctgtaaccc aggctggggc tgcgaaggtg cgatcaacca ccagcttgcc gcgtatggac
     2821 tgaccaatac cgtgacgcat aatcagggga actacgcagc gatgatggct gacaccatca
     2881 gtcgttacaa agagggtaag ccggtgtttt actacacctg gacgccgtac tgggtgagta
     2941 acgaactgaa accggggaaa gatgtggtct ggttgcaggt gccgttctcc gcactgccgg
     3001 gcgataaaaa tgccgatacc aaactgccga atggcgcgaa ttacggcttc ccggtcagta
     3061 ccatgcatat cgttgccaac aaagcctggg ccgagaaaaa cccggcagca gcgaaactgt
     3121 ttgccattat gcagttacca gtggcagata ttaacgccca gaacgccatt atgcatgacg
     3181 gcaaagcctc agaaggcgat attcagggcc acgttgatgg ctggatcaaa gcccaccagc
     3241 agcagttcga tggctgggtg aatgaggcgc tggcagcgca gaagtaattt ttattcgggc
     3301 ggataaggcg tttttgcctc atccgccgct ctgtacacaa tgcctgatgc gacgctggtg
     3361 cgtcttatca tacctacaaa ccacaccgca catttcaaca atctatcttt catcccatat
     3421 tcatcaacat ccgctattat tgatttccag cttaatcatc acctgatgaa caaaaataat
     3481 gactaaacct aatcatgagc ttagcccggc gctgatcgtg ctgatgtcta tcgccaccgg
     3541 tctggcggta gccagtaact attacgccca gccattgctc gacaccatcg cgcgtaactt
     3601 ttccctttcc gccagttcgg caggctttat tgttaccgcc gcgcagttgg gctatgccgc
     3661 aggtctgctg tttcttgttc ccctcggtga tatgtttgaa cgccgccgcc tgattgtctc
     3721 gatgacctta ctggcggcag gcggcatgtt aatcactgcc agcagtcagt cgctggcgat
     3781 gatgatcctc ggtacggcat taaccggttt attctcagtc gtggcacaaa ttctggttcc
     3841 gctggcagcg acgctggctt caccggacaa acgcggcaaa gtggtcggca ccattatgag
     3901 cgggctgctg ttggggatct tgctggcacg gaccgttgcc ggattgctgg cgagtctcgg
     3961 tggctggcga actgtctttt gggtcgcttc ggtattaatg gcactgatgg cgctggcgtt
     4021 atggcgtggt ctgccacaaa tgaaatcaga aacccacctc aactacccac agttgttggg
     4081 ttccgttttc agcatgttta tcagcaataa gatcctgcgc acccgcgcgt tgctgggctg
     4141 cctgaccttt gccaacttca gcattctctg gacctcaatg gcctttttgc ttgccgctcc
     4201 accttttaac tacagcgatg gtgtaattgg tctgtttggg cttgcgggag ctgccggagc
     4261 gttgggcgct cgtccggcgg gcggttttgc cgataagggc aaatcacacc acaccacaac
     4321 tttcggcctg ctgctgctgt tactttcatg gctggctatc tggtttggac acacttctgt
     4381 actggcgctg gttatcggca tcctggtgct ggacctcacc gtgcaggggg tgcacatcac
     4441 taaccagacg gtaatttatc gaatttaccc cgatgcgcgt aatcgcctga ctgcaggtta
     4501 catgaccagc tactttattg gcggtgctgc cggttcgcta atttcagcct cagcctggca
     4561 acatggcggt tgggctggcg tttgtctggc tggcgcgacg attgccctgg ttaacttact
     4621 ggtctggtgg cgaggttttc atcgtcagga agccgcaaat taagcaatca gcaaccgttt
     4681 tcgtggcttt acacttataa gggtgttaag aagcccatca gtctgataag gttaagatat
     4741 tcattcagtc tatttataat attaacaatc gttaagcgta cactctatgg aaagccctac
     4801 tccacagcct gctcctggtt cggcgacctt catggaagga tgcaaagaca gtttaccgat
     4861 tgttattagt tatattccgg tggcctttgc gttcggtctg aatgcgaccc gtctgggatt
     4921 ctctcctctc gaaagcgttt ttttctcctg catcatttat gcaggcgcga gccagttcgt
     4981 cattaccgcg atgctggcag ccgggagtag tttgtgggtt gctgcactga ccgtcatggc
     5041 aatggatgtt cgccatgttt tgtatggccc gtcactgcgt agccgtatta ttcagcgtct
     5101 gcaaaaatcg aaaaccgccc tgtgggcatt tggcctgacg gatgaggttt ttgccgccgc
     5161 aaccgcaaaa ctggtacgca ataatcgccg ctggagcgag aactggatga tcggcattgc
     5221 cttcagttca tggtcatcgt gggtatttgg tacggtaata ggggcattct ccggcagcgg
     5281 cttgctgcaa ggatatcccg ccgttgaagc agcattaggt tttatgcttc cggcactctt
     5341 tatgagtttc ctgctcgcct ctttccagcg caaacaatct ctttgcgtta ccgcagcgtt
     5401 agttggtgcc cttgcaggcg taacgctatt ttctattccc gtcgccattc tggcaggcat
     5461 tgtctgtggc tgcctcactg cgttaatcca ggcattctgg caaggagcgc ccgatgagct
     5521 atgaggtttt gctgcttggg ttactggttg gcacggcgaa ttattgcttc cgctatttgc
     5581 cgctgcgcct gcgtgtgggt aatgcccgcc caaccaaacg tggcgcgata ggcatattgc
     5641 tcgacaccat tggcatcgcc tcgatatgcg ctctgctggt tgtctctacc gcaccagaag
     5701 tgatgcacga tacacgccgt ttcgtgccca cactggtcgg cttcgcggta ctgggtgcca
     5761 gtttctataa aacacgcagc attatcatcc caacactgct tagtgcgctg gcctacgggc
     5821 tcgcctggaa agtgatggcg attatataac ccacaagaat catttttcta aaacaataca
     5881 tttactttat ttgtcactgt cgttactata tcggctgaaa ttaatgaggt catacccaaa
     5941 tggatagttc gtttacgccc attgaacaaa tgctaaaatt tcgcgccagc cgccacgaag
     6001 attttcctta tcaggagatc cttctgactc gtctttgcat gcacatgcaa agcaagctgc
     6061 tggagaaccg caataaaatg ctgaaggctc aggggattaa cgagacgttg tttatggcgt
     6121 tgattacgct ggagtctcag gaaaaccaca gtattcagcc ttctgaattg agttgtgctc
     6181 ttggatcatc ccgtaccaac gcgacgcgta ttgccgatga actggaaaaa cgcggttgga
     6241 tcgaacgtcg tgaaagcgat aacgatcgcc gctgcctgca tctgcaatta acggaaaaag
     6301 gtcacgagtt tttgcgcgag gttttaccac cgcagcataa ttgcctgcat caactctggt
     6361 ccgcgctcag cacaacagaa aaagatcagc tcgagcaaat cacccgcaaa ttgctctccc
     6421 gtctcgacca gatggaacaa gacggtgcgg ttctcgaagc gatgagctaa cgcgtcatct
     6481 cgctcaaaaa tccagattta taaaagaaaa aatgactggc cagcatcgca acatgctggc
     6541 ctttttggca agcaggtcgg ctcagccgat gagttaagaa gatcgtggag aacaatatga
     6601 gcgcaaatgc ggagactcaa accccgcagc aaccggtaaa gaagagcggc aaacgtaagc
     6661 gtctgctcct ccttctcacc ttgctcttta taattattgc cgtagcgata gggatttatt
     6721 ggtttttggt actgcgtcat ttcgaagaaa ccgatgacgc atacgtggca gggaatcaga
     6781 ttcaaattat gtctcaggtg tctggcagcg tgacgaaagt ctgggccgat aacaccgatt
     6841 ttgtaaaaga aggcgacgtg ctggtcactc tcgacccgac agatgctcgc caggcatttg
     6901 aaaaagccaa aacggcactg gcttccagcg ttcgccaaac ccaccagctg atgattaaca
     6961 gcaaacagtt gcaggcgaat attgaggtgc aaaaaatcgc cctcgcgaaa gcacaaagcg
     7021 actacaaccg ccgtgtgccg ctgggcaatg ccaacctgat tggtcgcgaa gagctgcaac
     7081 acgcccgcga cgccgtcacc agtgcccagg cacaactgga cgtcgctatt caacaataca
     7141 atgccaatca ggcgatgatt ctggggacga aactggaaga tcagcctgcc gtgcaacagg
     7201 ctgccaccga agtacgtaac gcctggctgg cgctggagcg tacccgtatt gtcagtccga
     7261 tgaccggtta tgtctcccgc cgcgcggtac agcctggggc gcaaattagc ccaacgacgc
     7321 cgctgatggc ggtcgttcca gccaccaata tgtgggtgga tgccaacttt aaagagacgc
     7381 agattgccaa tatgcgtatc ggtcaatcgg tcaccatcac caccgatatt tacggcgatg
     7441 atgtgaaata caccggaaaa gtggttggtc tggatatggg cacaggtagc gcgttctcac
     7501 tgcttccggc gcaaaatgcg accggtaact ggatcaaagt cgttcagcgt ctgcctgtgc
     7561 gtattgaact ggaccagaaa cagctggagc aatacccgct gcgtatcggt ttatccacgc
     7621 tggtgagcgt caataccact aaccgtgacg gtcaggtact ggcaaataaa gtacgttcca
     7681 caccggtagc ggtaagcacc gcgcgtgaaa tcagcctggc acctgtcaat aaactgatcg
     7741 acgatatcgt aaaagctaac gctggctaat ccagaggtgc gtgtgatgca acagcaaaaa
     7801 ccgctggaag gcgcgcaact ggtcattatg acgattgcgc tgtcactggc gacattcatg
     7861 caggtgctgg actccaccat tgctaacgtg gcgatcccca ctatcgccgg gaatctgggc
     7921 tcatcgctca gccagggaac gtgggtaatc acttctttcg gggtggcgaa tgccatctcg
     7981 atcccgctta ccggctggct ggcaaagcgc gtcggggaag tgaaactgtt cctctggtcc
     8041 accatcgcct ttgctattgc gtcgtgggcg tgtggtgtct ccagcagcct gaatatgctg
     8101 atcttcttcc gcgtgattca ggggattgtc gccgggccgt taattccgct ttcgcaaagt
     8161 ctattgctga ataactaccc gccagccaaa cgctcgatcg cgctggcgtt gtggtcgatg
     8221 acggtgattg tcgcgccaat ttgcggcccg atcctcggcg ggtatatcag tgacaattac
     8281 cactggggct ggatattctt catcaacgta ccgattggcg tggcggtggt gttgatgaca
     8341 ctgcaaaccc tgcgcggacg cgaaacccgc accgaacggc ggcggattga tgccgtgggg
     8401 ctggcactgc tggttattgg tatcggcagc ctgcagatta tgctcgaccg cggtaaagag
     8461 ctggactggt tctcatcaca ggaaattatc atcctcaccg tggtggcggt ggtggctatc
     8521 tgcttcctga ttgtctggga gctgaccgac gataacccga tagtcgatct gtcgttgttt
     8581 aagtcgcgca acttcaccat cggctgcttg tgtatcagcc tcgcgtatat gctctacttc
     8641 ggcgcgattg ttctgctgcc gcagttgttg caggaggtct acggttacac ggcaacgtgg
     8701 gcaggtctgg cctctgcgcc ggtaggaatt attccggtga tcctgtcgcc gattatcggc
     8761 cgcttcgcgc ataaactgga tatgcggcgg ctggtaacct tcagctttat tatgtatgcc
     8821 gtctgcttct actggcgtgc ctataccttt gaaccgggta tggattttgg cgcgtcggcc
     8881 tggccgcagt ttatccaggg ttttgcggtg gcctgcttct ttatgccgct aaccaccatt
     8941 acgctgtccg gtttgccacc ggaacgactg gcggcagcat cgagcctctc caactttacg
     9001 cgaacgctgg cggggtctat cggcacgtcg ataaccacga ccatgtggac caaccgcgag
     9061 tcgctgcacc atgcgcagtt gactgagtcg gtaaacccgt tcaacccgaa tgcccaggcg
     9121 atgtacagtc aactggaagg gcttgggatg acgcaacagc aggcatcagg ctggattgcc
     9181 cagcagatca ccaatcaggg gctgattatt tccgccaatg agatcttctg gatgtcagcc
     9241 gggatattcc tcgtcctgct ggggctggtg tggtttgcta aaccgccatt tggcgcaggt
     9301 ggcggcggag gcggtgcgca ctaagtacaa ctaagccagt tcatttgaac tggctttttt
     9361 caattaattg tgaagatagt ttactgacta gatgtgcagt tcctgcaact tctctttcgg
     9421 cagcgccagt tcttcgttgc tgttgatgcg cacgtcacgt tccagaatgc tacgcgcaat
     9481 atcctgcgct tcctgcaacg agtgcatctg gtaagtgcca cactggtaga cgttcagttc
     9541 cgggatctga ttctgatcct gcactttcag cacgtcttcc attgccgctt tccaggcatc
     9601 agcgacacgc tgctcatctg gcgtaccaat cagactcata taaaaaccgg tgcggcagcc
     9661 cattggcgag atatcgataa tctctacgcc attaccgtta agatggttac gcataaaacc
     9721 agcaaacagg tgctccaggg tatggatccc tctttctggc atcacttctt tgttcggcac
     9781 gcagaagcgc agatcgaaca cggtgattgc gtcgccatgc ggggtgttca ttgttttcgc
     9841 cacccgaact gcaggcgctt ccatccgggt atgatcgact gtgaagctat ctaacaacgg
     9901 catttagcca cctccggtaa tttttttaaa aattttctga actctttctt cccaggcgag
     9961 tctgagtata tgaaagacgc gcatttgtta tcatcatccc tgaattcaga gatgaaattt
    10021 tggccactca cgagtggcct ttttcttttc tgtcaggcgt gtttttccag ccacaccgca
    10081 aacggttcgg tatcagcggc ttccatttcc tgctgacggc gttcagacgc ctcgcgctcg
    10141 gcgacaaaat cctcttcgcg cagaatttcc agcggctctt cacgcagcag attacggtac
    10201 gcttcagcaa acgctttgcc tgttccgcca ataccagtat caatcataga ccttaagata
    10261 cgggcagaga aagtcagatc gggattatcg aagcaggcga ccagttcatc acacactttc
    10321 tgatacgctt cgccgccgtt aatgctatcc agcgtttgcg cgacgcgttt cagatcgcgg
    10381 aacagatctt tacccacctg cggtaacggg aactgcgcag tttcgcagcc gatacccagc
    10441 gtcaggcccg gtttgcgacc ttcgaggatc acccggttcc agttaacgcg tgtacaggca
    10501 agttcgctac tgctcatttc cggtgcatca gccagcgcac accagaccat aaacaggtcg
    10561 aggaatcgca cctgctgttc atctacacca atcggcgaga atgggttgat gtccagcgaa
    10621 cgcacttcaa tatattcaat gccgccacgt aacagcgcat cagaaggcga ctcgccgctg
    10681 cgggtaacgc gttttggacg aatcggcgcg tacagttcgt tttcaatctg cagcacgttg
    10741 ctgttgattt gcagccgctt accgtctttc tcaataccaa tcttcgcgta ctcttccgat
    10801 ggcgttttga ttgcctgttt aaggcccgcc acgtactcgt agagatcatt gaaggtgata
    10861 ccaagattgc tttgcgattt attggtatag ccaagatcgc tcaaacgaag agaggtcgca
    10921 tacggcaggt aatacatacc gcactcggtt ttctcaaacg gcagcgacgt tggttttcct
    10981 tgcaagaaag aagaacaaat cgctggagac gcaccaaaca gataaggaat gacccaaccg
    11041 aaacgatagt aattgcggat aacgcggaaa tagcccgcag aaattttctc tttggcatca
    11101 gcgcccgaga tatcaccgca cttcgcttgc cagaatgcca ttggcaaaga gaaattgtag
    11161 tgcacgccgg aaatggtttg catcagcgcg ccgtagcgat ttttcagccc ttcacgatac
    11221 agcgttttaa agcgtccggt gttagaagtg ccgtactgtg ccagttcgat gtcctgacct
    11281 tctgcgatgt agcatggcat acttaacggc cacatccgct catcgcccat attgcgcgcc
    11341 gtataacgat gcagatcgcg cataaaggtc aacatatgtt caatatcacc atccactggt
    11401 gtaatgaatt ccagcaatgc ttccgcaaaa tcggtagtaa tccatttgtg cgtcagtgcg
    11461 gaacctaatg cttcaggatg acctgttgtt gccagtgttc catcagcatt aacacgcaaa
    11521 gtttcgcgtt ccagcccacg ctgtatcccc tttaacgcct gaggatgttt ttccagccag
    11581 gccagcgcct gtgatacgtc cgggatcaaa ttgacctccc gcctgtcaaa atcgttttaa
    11641 ttagcataac tgtaatggtg accatatgtg caggcctaca attagtgcca ccacatcatg
    11701 ccctgaacgg tagctgctgc aactgcaaca tagcgtaacg ctttaccaag gcacaaaaaa
    11761 aagattaccg gtccccacga gatgcgcatc catcccgcta acagacacag taaatcgcca
    11821 accacgggca tccagcttaa taatagcgtg actgcaccat agcgtttcag ccagccggta
    11881 gctttctctt gccagcgcga tgttttacgc aatggaaaga aacgcccaag gataacgtta
    11941 gttaaccctc caaggctatt acccattgtt gctgttaaaa ctaaaaccca gggatgactg
    12001 atcccggaaa gcaacattgc caccagcacg acttcggagt tgccgggtaa tagtgtagcg
    12061 ctgagaaaac tactggcaaa caacgagaaa agcgataacg cttcactcac agcaagcgaa
    12121 catccacagc gtccatgcct gctgcacggg ccgcctgaat accgaaatcg gcatcttcaa
    12181 agaccacaca ctgcgtcggt tgcacgccca tacgctgcgc gcacaacaaa aatgtgtctg
    12241 gcgcgggttt atggtgtttg acgtgatcgg cagcaacgac ggcgtcaaaa taacggcgta
    12301 atcccaggtg tgccagcaat gcctcagcga tggcgctttc actccccgtt cctacagcca
    12361 ttgggcgacg accatgccag cttttcacca cttcaacaag aggaagcggc tcgacactat
    12421 ccagcagcat acttcttact gcttctgttt tttcacgcgc taacgcatgc gggtcgagat
    12481 cggcctgatt cagctcaata atcgcctgag caatacgcca ggtgggcgag ccattaagcg
    12541 caatcatcgc ctgaacgtcg tactgaagac cgtagtgccc taatacttcg cgccacgctt
    12601 tacggtgcgt aggctccgta tccaggattg tgccatccat atcaaaaatt aaacctgcat
    12661 aacgctcgta catggtcttc tcgcaagtcg aaaaatatga cgctacttta gcgtaattgc
    12721 ttgattttgt cgctgatggc gaaggagaag aaaattcagg aaatggataa agtagttatt
    12781 tagaaatgag atatttttga aggaaatttt ttggagaaga tggtgcatcc gggaggatga
    12841 ctcactggcg ttcgcccttc gggccgttgc tggccggcgt tatcctccct ggtgcctgcg
    12901 gttaataccg ctacctcttc gatatcttca ttgctgaagg ttacggagaa gatggtgcat
    12961 ccgggaggat tcgaacctcc gaccgctcgg ttcgtagccg agtactctat ccagctgagc
    13021 tacggatgca tcgggaaaat ttattttatt gctgatattg ataccgctac taaagccata
    13081 tcaagtaaga gatggtgcat ccgggaggat tcgaacctcc gaccgctcgg ttcgtagccg
    13141 agtactctat ccagctgagc tacggatgca tcgggaaact tactttactg cagatttttt
    13201 gataccgcca ctaaagccgt atcaagtaag agatggtgca tccgggagga ttcgaacctc
    13261 cgaccgctcg gttcgtagcc gagtactcta tccagctgag ctacggatgc aaatggcggt
    13321 gaggcgggga ttcgaacccc ggatgcagct tttgaccgca tactccctta gcaggggagc
    13381 gccttcagcc tctcggccac ctcaccacac gcctcttacg agtgcttcga agaacttgtt
    13441 tatcgctcat cgtcgctgcg tggcgcacat attactttct gagacttata agtcaaacaa
    13501 tttttcccac acttttatcg tttgcacact tcacgctcaa ttagtctgta aaaacgtcaa
    13561 aaagagtgtt ttatcaacag aaaaacggag gtctgacaga tagcagtaat gcaaaaaaat
    13621 ggagacttaa gttgaatgaa cgggagtaaa gcgaaaagac aatggagtga aagagaaatt
    13681 ttgagggtgc gtctcaccga taaagatgag acgcggaaag attagtaact ggactgctgg
    13741 gatttttcag cctggatacg ctggtagatc tcttcacggt gaacagaaac ttccttcggg
    13801 gcatttacgc caatacgtac ctggttgccc tttaccccta aaactgtcac ggtgacctca
    13861 tccccaatca tgagggtctc accaactcga cgagtcagaa tcagcattct ttgctccttg
    13921 aaagattaaa agagtcgggt ctctctgtat cccggcatta tccatcatat aacgccaaaa
    13981 agtaagcaat gacaaacaca ttacatctaa gcagtcatgg cattacattc tgttaaacct
    14041 aagtttagcc gatatacaca acttcaacct gactttatcg ttgtcgatag cgttaatgcg
    14101 aatgccgtga agcgagtcca cggcattgcc tgacgcttat attattgcaa tttcgcgctg
    14161 acccagcctt tcacactggc taacgctgca ggtaaggccg cagcatccgt accaccggct
    14221 tgcgccatgt caggacgtcc accacccttg ccgcccacct gctgagcgac cataccaatc
    14281 agctcccctg ctttcacacg atctgtgacg tccttagata cgcctgcaat cagagaaacc
    14341 ttaccttcgg ctaccgttgc cagcacgata attgtcgacc ccagctgatt ttttaaatcg
    14401 tcaaccatgg tacgcaacat tttcggctca acaccgctaa gctcgctaac caacagctta
    14461 acaccattaa catcaattgc cttactggaa agatttgcgc tctcctgtgc ggcagcttgt
    14521 tctttaagct gttgtaactc tttttccaac tgacgcgtac gttccagtac tgaacgcact
    14581 ttatcagcca gattattgct atcgcctttc agcagatgcg cgacttcgct taagcgatca
    14641 ctgtctgcat gaacggtggc gatagcgcct tctccggtta ccgcttcgat acgacgaacg
    14701 cctgcagcag tacccgattc agagatgatg cggaacagac caatatcacc agtgcggctg
    14761 gcgtgagtac cgccacacaa ctcggtggag aaatcaccca tgctcagcac gcgtacgcgc
    14821 tcatcatact tctcgccaaa cagcgccatc gcacctttcg ctttcgccgc ttcgagatcc
    14881 atgatgttgg tttcgatcgg caagttacgg cgaatctgtg cgttcaccag gtcttcgacc
    14941 gcacgaatct cttctggttt catcgcttcg ttgtgtgaga agtcgaagcg cagcactttg
    15001 tcgttaacca gtgaaccttt ctgcgataca tgagtaccca gaacctggcg cagcgcagcg
    15061 tgcatcaggt gcgttgcgga gtgattcaga cgaatacggg cgcgacgagc ctcatcaaca
    15121 tcagcctgca cagcgtcgcc cactttcaga gaacccgtag caagtttacc gatgtgacca
    15181 atcgcctggc cgtatttctg agtatcttcc accgcaaagg agaagttagc gcctttcagt
    15241 tcgcctttat caccaacctg accgccggat tccgcataga atggcgtttg atccagcacg
    15301 accacagctt cctggcctgc attgacggca tcaaccgctt taccatcaac aaacagcgcg
    15361 gtcactttgc cgttcagttc cagatggtca tagcctttaa attcagatgc actgtcaaca
    15421 cggatcattg cgttgtaatc ggcaccaaag ccgctggctt cgcgcgcacg acgacgctgc
    15481 tcttccattg ctgcttcaaa tccagcttcg tcaactttga tgttgcgctc acgacaaaca
    15541 tcagccgtca ggtcaaccgg gaagccatag gtgtcgtaca aacggaaagc agtttcacca
    15601 tccagcgtat caccagaaag ttttgccagc tcttcatcca gcaacgccag accgcgctcc
    15661 agagtacgag caaactgctc ttcttcagtc ttcagcacct gctcaacctg cgcctgctgg
    15721 cgtttcaggt cttcacccgc agagcccata acgtcgatca gcggaccaac cagtttgtag
    15781 aaaaaggttt ctttcgcgcc gagcatatta ccgtgacgca ctgcgcgacg aatgatacga
    15841 cgcagtacat aaccacggtt ttcgttggac ggcattacgc catccgcgat caggaacgca
    15901 caagaacgaa tgtggtcagc gattacgcgc agcgatttat tgctcagatc ggttgcgcca
    15961 gtgactttcg ctaccgcctg gatcagcgtg cggaacaagt cgatgtcata gttagagtta
    16021 acgtgttgca gcaccgcagc aatacgctcc agacccatac cggtatctac agacggcttc
    16081 ggcagcggtt ccatcgtgcc atcggcctgg cggttgaact gcatgaagac gatgttccag
    16141 atctcaatgt agcgatcgcc gtcttcttcc ggacttcccg gagggccacc ccaaatgtgg
    16201 tcgccgtgat cgtagaagat ttcggtgcac gggccgcacg gaccagtgtc acccatctgc
    16261 cagaagttgt cagatgcgta tggcgcacct ttgttatcgc cgatgcgaat aatacgttcg
    16321 cgcgggatcc ctacttcttt ttcccagatt tcgtaggctt cgtcgtcgct ttcatagacg
    16381 gtaacccaca gacgctcttt cggcagggca aaccattttt cactggtcag cagttcccat
    16441 gcaaactgaa tggcatcgtg tttgaaatag tcgccgaagc tgaagttgcc cagcatttcg
    16501 aagaaggtat ggtgacgcgc ggtgtaaccg acgttttcca ggtcgttgtg tttaccaccc
    16561 gcacgcacgc agcgttggga agtggtagcg cgggaataat tacgcttgtc gagcccaagg
    16621 aacacatcct tgaactggtt catcccggcg ttggtaaaca acaaagttgg gtcgttatgg
    16681 ggtaccaggg agctgctggc aactacctga tgtcccttac tatggaaaaa gtcgagaaac
    16741 gcctgacgga tctcagcggt gctcttgctc ataattatcc tgaaatcaag ctaacgaaat
    16801 atcgctacca gccgttgcgt gtcgttaacc gcccggctgg taactgaaaa gtgggaataa
    16861 gataagtttt cttgactggg aagtaaaatc ccgtatgcgt tcagtcggca aaatttcgcc
    16921 aaatatcctg gatatcttcc atcagatagc cacgatagag cagaaaacgc tggatcttaa
    16981 ctttttctga aaaggcagtt ggcaaaggtt cgccatattt tcgcgtcgcc tgatcgcgcg
    17041 ccagttcgca ccagtcgatg tcacattcac gcatcgcttt ttctgtcgct tcgcgggaaa
    17101 tacctttctg attcagttcc tgacgaatac gcgcaggtcc ataacctttg cgactacgac
    17161 tggcaataaa gcgcgccaca aatcggctgt catcgagata gccatgttca tggcaccagg
    17221 cgataacccg ctcgtaatct tctgccgtag catcaatctc ttccgggcca tttttgccca
    17281 taatcggtgc cgcgagttta cgccgcagtt cttgctcact gtgatcgcgc accgccagaa
    17341 tgcgtaccgc acgatccaac aggcgagcat atgccgggcg acgggatgtt gattctgtca
    17401 tggcatatcc ttacaactta aaaaagcaaa agggccgcag atgcgaccct tgtgtatcaa
    17461 acaagacgat taaaaatctt cgttagtttc tgctacgcct tcgctgtcat ctacagagaa
    17521 atccggcgtt gagttcgggt tgctcagcag caactcacgt actttcttct cgatctcttt
    17581 cgcggtttcc gggttatctt tcagccaggc agtcgcattc gctttaccct gaccgatctt
    17641 ctcacctttg tagctgtacc acgcgcctgc tttctcgatc agcttctctt tcacgcccag
    17701 gtcaaccagc tcgccgtaga agttgatacc ttcgccgtag aggatctgga attcagcctg
    17761 tttaaacggc gcagcgattt tgttcttcac cactttcacg cgggtttcgc tacccaccac
    17821 gttttcgccc tctttcaccg cgccgatacg acggatgtcg agacgaacag aggcgtagaa
    17881 tttcagcgcg ttaccaccgg tagtggtttc cgggttaccg aacatcacac caattttcat
    17941 acggatctgg ttgatgaaga tcagcagcgt gttggactgc ttcaggttac ccgccagctt
    18001 acgcatcgcc tggctcatca tacgtgccgc aaggcccatg tgagagtcgc cgatttcgcc
    18061 ttcgatttcc gctttcggcg tcagtgccgc cacggagtca acgacgataa cgtctactgc
    18121 gccagaacgc gccagggcgt cacagatttc cagtgcctgc tcgccggtgt ccggctggga
    18181 gcacagcagg ttgtcgatat cgacgcccag tttacgtgcg tagattgggt ccagcgcgtg
    18241 ttcagcatcg ataaacgcac aagttttacc ttcgcgctgg gctgcggcga tcacctgcaa
    18301 cgtcagcgtg gttttaccgg aagattccgg tccgtagatt tcgacgatac ggcccatcgg
    18361 cagaccacct gccccaagcg cgatatccag tgaaagcgaa ccggtagaga tggtttccac
    18421 atccatggaa cggtcttcac ccaggcgcat gatggagcct ttaccaaatt gtttctcaat
    18481 ctggcccagt gctgccgcca acgctttctg tttgttttcg tcgatagcca tttttactcc
    18541 tgtcatgccg ggtaataccg gatagtcaat atgttctgtt gaagcaatta tactgtatgc
    18601 tcatacagta tcaagtgttt tgtagaaatt gttgccacaa ggtctgcaat gcatacgcag
    18661 tagcctgacg acgcaccgca tcacggtcac cgctgaagca ttcccggcgg gtaatacctt
    18721 cgccgcgggc ggtggcaaaa gcaaaccaga cggtgccgac aggcttctct tcactgccgc
    18781 catccggccc ggcgatacca ctaatagaca cggcataatc agcacgagcc gctttcagtg
    18841 cgcctatcgc catttccacc acgacaggct cgctcaccgc gccatgctgc gccagcgtct
    18901 cttcacgtac gccgatcatt tgcgctttgg cttcgttact gtaggtgaca aatccgcgtt
    18961 caaaccaggc ggagctaccg gcaatatcgg taatcacttt cgctacccaa ccaccggtac
    19021 aagactcagc agttgttacg gttgcgccac gggctttcag cgcctgccca acctgttcgc
    19081 ttaactgcat cagttcactg tcagtcatca caacctctgt cagtcaaaaa tttatgccgg
    19141 acaagatagc actttcgtca ggaagatggt gttggcgttg caattttacg aggaggattc
    19201 agaaaaaagc tgattagcca gagggaagct cacgcccccc tcttgcaaat agttactgca
    19261 cgcgcgccag cgccacggct tgtcctaact gccagaccgc cattgcgtaa tgggtgctgt
    19321 ggttataacg ggtaatggtg tagaagttcg gcagaccgta ccagtactgg taacctgttc
    19381 caacatccag acgcagcagg ctggcttgtt gatggttgcc cagcggctgc tgtggcgtta
    19441 aacctgccgc ggcaagttgt gaaatgctgt acctggtttt gaagccattt ggcaagcctg
    19501 gagcctgacc gtttgccatc accgcaacct gatcaccttt cacccagccg tgcgctttga
    19561 aatagttcgc cacactacca atggcatcaa ccggatccca caggttgata tgcccgtcgc
    19621 cgctgaaatc taccgcatat tgtttgtaag acgacggcat aaactgtccg tagcccatcg
    19681 ccccggcaaa ggaacctttc agattgagcg gatcgtcctg ctcgtcgcgc gccatcagca
    19741 ggaaggtttc cagctcgcca gagaaatact ccgcgcggcg tgggtagtta aatgacagcg
    19801 ttgccagcgc atcgaggatg cgagttttcc ccatcacgcg tccccagcgg gtttcaacgc
    19861 cgataatccc gacgataatt tctggcggta cgccatacac ttgccatgcg cgattcagcg
    19921 catcttcata ctgattccag aaaaccacgc cgttttgcac gttgtccggc gtaataaatt
    19981 ttttgcgata acgcagccat gcgccgttcg gacctgatgg cggcttcacc gatgtggttg
    20041 gtgcctggtt atccatcagc cgcagtaccg aatccagacg tttcgcctgg gagagaattt
    20101 cctgcaactg ctgacgattg aaaccgtgtt tgttcaccat tttgtcgatg aactgctggg
    20161 cattcgggtt attggcgaag tcaccgccca tctgcatcac attgtgctgc ggctcaagca
    20221 ggaagccgcc agacggcgtt ccggtggtcg tttcagtctc agtaggtttt ggcttgctgc
    20281 tacaggcggc aagcaacaca aaaaggggaa gcaatgttac ataacgacgc ttgaacatga
    20341 ggggtccatt taacagattc aaccaggggc aagtatggta aagcatcccg ccccgcacaa
    20401 ggaagcggta gtcactgccc gatacggact ttacataact caactcattc tcctcactac
    20461 cttctttata taaactttca aaataaaata tttatctttc attttgcgat caaaataaca
    20521 cttttaaatc tttcaatctg attagattag attgccgttt ggtaataaaa caataaatcc
    20581 tgaaggagag aacaatgata gaaaccatta ctcatggcgc agagtggttc atcgggctgt
    20641 tccagaaagg cggagaagtg tttaccggga tggtaaccgg cattcttccg ctgttgatta
    20701 gtctgttggt tatcatgaac gcactgatta attttatcgg tcagcatcgt attgaacgtt
    20761 ttgctcaacg ttgcgccggt aaccctgttt cccgttatct gctgttaccg tgcattggca
    20821 cgtttgtctt ttgcaatccg atgaccttaa gcctgggtcg ctttatgccg gaaaagtaca
    20881 aacccagcta ctacgcggcc gcctcttata gctgccactc aatgaatggc ctcttccccc
    20941 atatcaaccc aggcgaactg tttgtttatc ttggcattgc cagcggtctg acaacgctga
    21001 acctgccact tggcccactg gcggtgagtt atctgctggt tggtctggtc accaacttct
    21061 tccgcggctg ggtgaccgat ctgaccaccg ctatttttga gaaaaagatg ggcattcaac
    21121 ttgaacaaaa agttcatctg gcaggagcaa catcatgacg cgtattcgga tcgaaaaagg
    21181 aacgggtggc tggggcggcc cgcttgagct ggaagccaaa ccgggaaaaa aaatcgtcta
    21241 tatcaccgcc ggtacccggc ctgcgattgt tgacaaactg gcacagctta ctggctggca
    21301 ggctattgac ggatttaaag aaggtgaacc cgcggaggcg gaaattggtg tcgcggtaat
    21361 cgactgtggc ggcacattac gctgcggcat ctatccgaaa cgacgtattc ccaccattaa
    21421 tatccactcg acgggcaagt ccggtccact ggcgcagtac attgtggaag atatttatgt
    21481 ctctggcgta aaagaagaaa acatcactgt agtgggtgat gcgacaccac aaccctcttc
    21541 cgtgggccgt gactatgaca ccagcaagaa aatcaccgaa caaagcgatg gtttactggc
    21601 gaaggtggga atgggtatgg gttctgccgt tgccgtgctg ttccagtctg gccgtgacac
    21661 catcgacacg gtattaaaaa ccattctgcc gtttatggcg ttcgtctcgg cgctcattgg
    21721 catcattatg gcttctggcc ttggtgactg gattgcccac ggtcttgctc cgctggcgag
    21781 ccatccactg ggtctggtca tgctggcgct catctgctcc ttcccgctgc tttcaccttt
    21841 cctcggccca ggcgcagtta tcgcgcaggt tatcggcgta ttgattggtg tgcagattgg
    21901 tctcggcaat attccgccgc atctggcttt acctgcactg tttgccatca acgcgcaggc
    21961 ggcctgcgac ttcatcccgg tcggtttgtc gctggcggaa gctcgtcagg acacggttcg
    22021 cgtcggtgtc ccttctgttc tggtgagccg ctttttaacc ggcgcgccaa ctgtactgat
    22081 cgcctggttt gtctccggtt ttatctatca atagaggctg aaacatgacc gttatttatc
    22141 agaccaccat cacccgtatt ggcgcgagcg ccactgacgc cctcagcgac cagatgctca
    22201 tcacctttcg tgaaggcgcg cctgcggatc tcgaagagta ttgcttcatt cattgccacg
    22261 gcgagttgaa aggtgcactc catcccggtt tgcaattttc actcgggcag catcgctatc
    22321 cggtgaccgc cgttggcagc gtggcggaag acaaccttcg cgaactgggt catgtcaccc
    22381 tgcgcttcga tggtttaaac gaagcggaat tcccgggcac tgtccatgtg gcaggccctg
    22441 tacccgacga tatcgcgccg ggatcggttt tgaagtttga atctgttaag gagtaaaaaa
    22501 tgaatcaggt tgccgttgtc atcggtggtg ggcaaacctt aggcgcgttc ctgtgccacg
    22561 gtctggctgc cgaggggtat cgcgtcgcgg ttgtcgatat tcagagcgac aaagctgcaa
    22621 atgtggcgca agaaattaac gccgaatatg gtgaaggaac agcttacggt tttggtgctg
    22681 acgccaccag cgagcaaagc gttctggcgc tttctcgtgg ggtagatgaa atctttggtc
    22741 gcgtggattt gctggtctac agcgccggaa tagcaaaagc agcctttatc agcgacttcc
    22801 agctcggcga ttttgaccgt tcgctacagg tgaatctggt gggttatttc ctgtgtgcgc
    22861 gtgaattttc gcgtttgatg atccgcgacg ggattcaggg gcgcattatt cagatcaact
    22921 cgaaatccgg caaagtgggc agcaaacaca actctggcta cagcgcagcg aaatttggtg
    22981 gcgtcgggct gactcaatca ctggcgctgg atctggcgga gtacggcatt acggtgcatt
    23041 cactgatgct cggtaacctg ctgaaatcgc cgatgttcca gtcactgttg ccacaatacg
    23101 cgaccaagct gggtatcaaa ccggatcaag tcgagcagta ttacatcgat aaagtaccgc
    23161 tcaaacgcgg ctgcgattat caggatgtgc tgaatatgct gctgttctac gccagtccta
    23221 aggcgtcgta ctgcactggt cagtcgatca atgtcaccgg cggtcaggtg atgttctgat
    23281 taacagcgga gatccgttaa ggatctccgc gagactaata gaatgcctga tgcgctacgc
    23341 ttatcaggcc tacaggactt ccgccactac attaaggaga agttatggta tccgcactca
    23401 tcaccgtcgc cgttatcgcc tggtgtgcgc aactggcctt aggcggctgg caaatttctc
    23461 gttttaaccg tgccttcgac acactatgcc agcaagggcg ggttggcgtg ggccgttcca
    23521 gcgggcgctt taaaccgcgg gtcgtggtcg ccatcgccct ggacgatcag cagcgcatcg
    23581 tcgacacctt gtttatgaaa ggactgaccg tcttcgcccg accgcaaaaa attcccgcaa
    23641 ttaccggtat gcatgcgggt gatttacagc ccgatgtgat ctttccccat gatccactat
    23701 cacagaatgc tctatcattg gcgcttaaac tgaaacgtgg ataatttcgt tgtgaatgtt
    23761 acttgcttgc gaagttatca ttttgaaacc taaatcaggt aatcacgccc atgaaacctc
    23821 gtcagcgtca ggccgccatt ctggagtatc tgcaaaagca gggtaaatgc tcggttgaag
    23881 aattggcgca atactttgac accacaggca caaccattcg caaagatctg gtcattctgg
    23941 aacatgccgg aaccgtcatt cgtacttatg gcggagtggt gttgaataaa gaggaatccg
    24001 atccgcctat cgatcataaa acactcatca acacccacaa gaaagagctg attgcagaag
    24061 ctgccgttag ttttatccat gatggcgatt cgatcattct tgatgctggc agtaccgttt
    24121 tgcagatggt tcccctgctc tcgcgcttta ataacatcac agtgatgacc aacagcctgc
    24181 atatcgtcaa tgcgctatcc gaactggata acgaacaaac tatcctgatg ccaggcggaa
    24241 catttcgtaa aaaatcggcc tcatttcacg ggcaactggc agagaatgcc ttcgagcatt
    24301 tcaccttcga taaattgttt atgggcaccg acggcatcga tctcaatgcg ggcgtaacca
    24361 cgttcaacga ggtttatacc gtcagtaagg caatgtgcaa tgccgcgcgc gaagtgattt
    24421 tgatggcgga ctcatcaaag tttggccgta aaagccccaa cgtagtttgc agtcttgaaa
    24481 gcgtcgataa gctaattacc gacgcaggta tcgatccagc gtttcgtcag gcgctggaaa
    24541 agaaagggat cgacgtgatc ataaccggag agagcaatga gtgaagcact actgaacgcg
    24601 ggacgtcaga cgttaatgct ggagttgcag gaagcaagcc gtttaccgga acgtctgggc
    24661 gatgattttg ttcgcgccgc caatatcatc ctgcactgcg aaggcaaagt ggtggtttcg
    24721 ggaattggca aatcgggcca cattggtaag aaaatcgccg caacgcttgc cagcaccggc
    24781 actcctgcct tttttgtcca tccggcagag gcattgcacg gcgacctggg gatgatcgaa
    24841 agccgcgatg tgatgctgtt tatctcttac tccggtggcg cgaaggaact ggatctgatt
    24901 attccgcgtc tggaagataa atctatcgcg ctgctggcga tgaccggcaa accgacgtca
    24961 ccgctgggcc tggcggcgaa agcggtgctg gatatctccg tagaacgcga agcctgtccg
    25021 atgcaccttg cgccgacctc cagcaccgtg aataccctga tgatgggtga cgcgctggcg
    25081 atggcggtca tgcaggcgcg cggatttaat gaagaagatt ttgcccgctc ccaccctgct
    25141 ggagcactgg gcgctcgctt gctgaataaa gtgcatcatc tgatgcgccg tgatgacgct
    25201 atcccgcagg tagcgttaac cgccagcgtg atggatgcga tgctggaact cagccgcact
    25261 ggtctggggc tggtggcggt atgtgacgct caacaacagg tacaaggcgt ctttaccgac
    25321 ggcgatttac gtcgctggct ggttggcggc ggtgcactca ccacgccagt caatgaagcg
    25381 atgacggtcg gcggcaccac gttgcaatcg caaagccgtg ccatcgacgc caaagaaatc
    25441 ctgatgaaac gcaaaatcac cgccgcaccg gtagtggatg aaaacggcaa actcaccggc
    25501 gcaattaacc tgcaggattt ctatcaggcc gggattattt aatccttcag ccccagacgt
    25561 ttcgccaacc gatgcaagtt ggcgacgtcg gtttccagca tccgtgcgct ggcagcccag
    25621 ttgtgatgat tttgtgccag tgcctgacga atggtttcac gctggaacgc ttctgtcgct
    25681 tcacgcaggt tttgcttaac gataggcacc gccgccgctt ctggcggcgg caacgtcacc
    25741 tcaggaaaag caaaatgttg cgcttcaaga atcacttcat cgccgctgcg ggtcgctctc
    25801 gccagcacca ccgcccgatg aatagcatgt tccagttcgc gcacgtttcc cggaaaactg
    25861 tagtgttgca gtaaatttcg cgccccggca cttaatacca cgcgggagag ccccagccgc
    25921 aaacgacact gctcgcagaa ataccccgcc agcagaatga catcatcgcc ccgctcacgc
    25981 agcggcggca ccgaaagtgg gaacacgctc aggcgatgaa acaaatcggc gcggaatcgc
    26041 cctgccagca cctcttcgcg taagtcgcgg ttagtcgccg ccagcacgcg cacatcgacc
    26101 cgcaaactgc ggtcatcgcc aacgcgctga atatcgccat actgcaacac cctcagcagc
    26161 ttggcctgca atgccaacga cagctcgccg atctcatcga gaaacagtgt gccgttatcc
    26221 gccatttcaa acttcccgct gcggttactg atagcgccag taaacgctcc tttcacatgc
    26281 ccgaacaact cactttccgc cacactttcc ggcagtgcgg cacagttgag atagaccagc
    26341 ggattcaccg cccttggcga ggtttcatga atcgctttcg ccaccagctc cttaccggtt
    26401 cccgtctcac cgctgattaa gacgttgaga tcggacgccg ccacaatctc aatctctttt
    26461 ttcaattgcg tcatgcctgg cgacaagcca atcatctgcg tctgtttcac cgcttcaaac
    26521 ggcgcggcat cgcccggcag catattctgg ctttccagtt gctcaatcag caacgcattg
    26581 cttaacgctc ccgccgccag cgcggcaatc aggcgtaact cttcgtcgct gaaaacatcg
    26641 aactgatcgg gttgcatccc gtcgagcgtc aatgcgccga tcaggttttg cccggcaaac
    26701 aatggcagac caacgcaggc gtgaaccttc agactctcct gcccgggaat caaaccgtca
    26761 tagggatcgg gcaattcgct gtctgcggga aagcgcacca cgtccccggc gcgggcaatc
    26821 gcttccagcc gtggatgccc ttccagcgca aagcgtctac cgagtacatc cttcgccagc
    26881 ccgtcgatgg caagcggaat aaactgccgc gagtcataac gtagcaacgc agaggcatca
    26941 cactccagca cctgacgcag cgtggtgatc aggcgctgaa aacgatcctg atgaccaatc
    27001 ccacgctgca attcgatggc gatattcgcc agcacatcaa cggaaaaact catctttgcc
    27061 tcactgtcaa tttgactata gatattgtca tatcgaccat tttattgata gtcattttga
    27121 ctactcatta atgagcacaa ttttatttat agagtaaaaa caatcagata aaaaactggc
    27181 acgcaatctg caattagcaa gacatctttt tagaacacgc tgaataaatt gaggttgcta
    27241 tgtctattgt ggtgaaaaat aacattcatt gggttggtca acgtgactgg gaagtgcgtg
    27301 attttcacgg tacagaatat aaaacgctgc gcggcagcag ctacaacagc tacctcatcc
    27361 gtgaagaaaa aaacgtgctg atcgacaccg tcgaccataa attcagccgc gaatttgtgc
    27421 agaacctgcg taatgaaatc gatctggcag atatcgatta catcgtaatt aaccatgctg
    27481 aagaggacca cgccggggcg ctgaccgaac tgatggcgca aattcccgat acgccgatct
    27541 actgtacagc caacgctatc gactcgataa atggtcatca ccatcatccg gagtggaatt
    27601 ttaatgtggt gaaaactggc gacacgctgg atatcggcaa cggcaaacag ctcatttttg
    27661 tcgaaacgcc aatgctgcac tggccggaca gcatgatgac ttacctgaca ggcgacgcgg
    27721 tgctattcag taacgatgct ttcggtcagc actactgcga cgagcatctg ttcaacgatg
    27781 aagtggatca gacggagctt ttcgagcagt gccagcgtta ctacgccaat atcctgacgc
    27841 cgttcagccg cctggtaacg ccgaaaatta ccgagatcct gggctttaac ttgccagtcg
    27901 atatgatagc gacctctcac ggcgtggtat ggcgcgataa cccgacgcaa attgtcgagc
    27961 tgtacctgaa atgggcggcg gattatcagg aagacagaat caccattttc tacgacacca
    28021 tgtcgaataa cacccgcatg atggctgacg ctatcgccca ggggattgcg gaaaccgacc
    28081 cacgcgtggc ggtgaaaatt ttcaacgtcg cccgaagcga taaaaacgaa atcctgacca
    28141 atgtcttccg ctcaaaaggc gtcctggtcg gcacttcgac gatgaataat gtgatgatgc
    28201 cgaaaatcgc cgggctggtg gaggagatga ccggattacg cttccgtaac aaacgcgcca
    28261 gtgctttcgg ctctcacggc tggagcggcg gtgcggtgga tcgtctttcc acgcgcctgc
    28321 aggatgcggg tttcgaaatg tcgcttagcc tgaaagccaa atggcgacca gaccaggacg
    28381 ctctggagtt atgtcgtgaa cacggtcgcg aaatcgcccg tcagtgggcg ctcgcgccgc
    28441 tgccgcagag cacggtgaat acggtggtta aagaagaaac ctctgccgcc acgacggctg
    28501 acctcggccc acggatgcaa tgcagcgtct gccagtggat ttacgatccg gcaaaaggtg
    28561 agccaatgca ggacgttgcg ccaggaacgc cgtggagtga agtcccggat aacttcctgt
    28621 gcccggaatg ctctctcggc aaagacgtct ttgacgaact ggcatcggag gcaaaatgag
    28681 caacggcatt gtgatcattg gttcgggctt cgccgcccgc caactggtga aaaatattcg
    28741 caaacaggac gccagtattc cattaactct gattgccgcc gacagcatgg atgagtacaa
    28801 caaacctgac ctcagccatg ttatcagtca ggggcaacgt gccgatgacc ttacccgcca
    28861 gacggcaggt gaatttgccg agcagtttaa tctgcgcttg tttccgcaca cctgggtaac
    28921 ggatatcgat gccgaagccc atgtggtgaa aagtcagaat aatcagtggc aatacgacaa
    28981 gttagtgctg gcaaccggtg ccagcgcctt tgtcccgcca gtgcccgggc gtgagttaat
    29041 gctgacgtta aatagtcagc aagagtatcg cgcctgtgaa acgcaactgc gggatgcccg
    29101 acgcgtgttg attgttggcg gtggcttgat tggtagcgag ctggcgatgg atttttgtcg
    29161 ggcaggcaaa gcggtcacgc taatcgacaa cgctgccagt attctggcgt cgttaatgcc
    29221 accggaagta agcagccgct tgcagcatcg gttgacggag atgggcgttc atctgctgtt
    29281 aaaatctcag ttgcagggac tggaaaaaac agattctggc attctggcaa cgctggaccg
    29341 ccagcgctgc attgaagtgg atgcggtaat tgccgccacc ggactgcgcc cggaaaccgc
    29401 cctggcacga cgcgccgggc tgacgattaa tcgtggcgtt tgcgtcgata gctatctgca
    29461 aaccagtaat gccgatattt atgcgctggg cgattgcgcg gaaattaacg gtcaggtatt
    29521 gccgttcctc cagccgattc aacttagcgc aatggtgctg gcaaaaaatc ttctcggcaa
    29581 taacacgccg ctgaaactac cggcgatgct ggtgaaaatc aaaacgccgg aattaccgct
    29641 gcatctggca ggcgaaaccc agcgtcagga tttacgctgg caaattaata ccgaacgcca
    29701 gggaatggtt gcgcgcggtg ttgacgatgc tgaccagctt cgcgcctttg tggtcagtga
    29761 ggatcggatg aaagaggcgt ttggattgtt gaaaacgttg ccgatgtagg catggttttc
    29821 tccctcgccc aaagggcgag gggactgtcc gcgctacttt taacgcttag ttacgccaca
    29881 tccgccacta tgcagcatgc aggatgcgcg ccgcagcaat aaccccctgc cccagagaca
    29941 agccgccatc acccgccggt aaactctgcg gaaagagtaa tgtgaaatca gcgagataat
    30001 gcgccaggcg tgtacgcagc aatcggttat gaataacccc accgctaaat accagcgtag
    30061 tgataccgcg catcgtggcc tgctcacgca tcaacgcggc aaaaccctgc gccagcgcat
    30121 catgaaacgc ccacgcgcgt tgattaaccg gtgcctgcca gttcagccac tgctgccaga
    30181 aggtggcgag atccagttga ttgtccacca gcggcatcgt caccggatgc gtcactccct
    30241 ggctcgaagc cgccagcgcc tcgagggcgc aagccgcttc accttcataa cttaacgtgg
    30301 ctggcgcaca gcccaacgcc gccgctacgg catcgaacaa acgtccacac gatgatgcca
    30361 gcggcgcgtt aattccacgc tcaatggccc gcgccagcac gctccagttt tgctgttgca
    30421 cacttgccgt ttcagggtaa ttctgccact ccggcacaaa gcgcaggcac tgcgccagca
    30481 ggttacgcca cggctgcttt gcagccaaat cgccccccgg aagcgccacc gcaggcaagc
    30541 cgcccaggtg ttcacattcg cgatagttca cccgcaggca ctcgccgccc cataaagcgc
    30601 cgttctcccc cataccgata ccgtcgagcg tcaacgcaat gacatcaccg ccatccagcg
    30661 gccagtgatg ttctgccaga cacgccgccg catgagcatg atgatgcagc accgtttgcg
    30721 tcggcagatt catttcgcgc gcccactggc tggagacata gcccggatgc gcgtcatgca
    30781 caacgtattg cggagtgaaa tcgtagatgt tttgcatcag gcgtaacgct tcgcgccact
    30841 gcatctggat gccatcgtca cttaaatcgc ccagatgctg actcaacacc gcttgtttac
    30901 cgcgcaccag gcagaaggta tttttcagat ccgcgccgag acacagcaca ggcggaacat
    30961 ttttaaagcc tggaggcaaa gccagcgcat ccggcacata cccccgcgaa cggcgcagca
    31021 tttcgccgtt ttcgcgcacc accgaatcat ccatccgctg cacgatgtcg cggttatgta
    31081 tcaagaatcc gtcggcaatc ccctgcaaat ccgccagcgc ctgttcgttg ctgatagctg
    31141 gtggtttacc gttcaggttg ccggaggtca tcaccagcgg gcattgcagt tcctgtaaca
    31201 gcaaatgttg gagcgggttc gcaggcaaca tcaccccaac ttcgttaagg ccaggggcga
    31261 tatcatcaca aagctcagga acgtattttt tatccaccag aacaatcggc gcggcgggcg
    31321 tggtaagcaa ctggcgcgca gcgtcaggta aaccgtcagc cactggcaac atgaccgcca
    31381 gcggtttcgc cgggcgatgt ttgcgtgccc gtagtgtcgc caccgcgtta ctgttacgcg
    31441 catcgcaggc gagatgaaat ccgccaatcc ctttgatggc gacaatgttg cccattttta
    31501 actgtgcgat agccgcctgt aatgccgcct cttgttctgc atgttcacca tgacttaccc
    31561 attcaagatg tgggccacac tccgggcagg ccaccggctg ggcgtggaag cgacgatcga
    31621 gcgggtcaca gtactctttg tcacaagccg gacacagcgg aaacgccgcc atcacggtaa
    31681 acgggcgatc gtaaggcatg gcgcgaataa tggtgaaacg cgggccacag tgggtacagt
    31741 tgataaacgg ataacgataa cgccgctcgc ctggggtatt catttcggca aggcaagcag
    31801 ggcaagtggc ggcatccggg acaatttgcg tattcatagt gccgcctgtg ctctggcgga
    31861 tagtgaactc agtgggcagt tgtgaccaga taaacggctc acgctcgacg ctatcaatac
    31921 gcgccagcgg cgggcagtgc tgatgcaact gcacaagaaa cgtttccggg tcttccagca
    31981 gccggacttc tacgccatcg ccgtcattac agacatcgcc gtgaagattt aattgctgtg
    32041 ccagttgcca gacaaacgga cgaaaaccga cgccctgcac tttgccacga atacgcagtt
    32101 ggacaccgca agatgtgttt tttgccattg agttattccc gccatcatga attgcgtaac
    32161 ccgcccagcc ggacacgaca gcgtcgtatc cggcaatcac aggtcggcga tactgcccgc
    32221 ttcgtattct acgaatattt ccgggaattc ctttgatgcc agaacagttc tgtaagattt
    32281 ttagaacatc agcgccgtac ggcgacgttt ttctgcgctc agttgttcaa gtttattacg
    32341 atcgacacaa atcagcgcat gggtcgggca agccgccata cacgccgggc cgtcttcacg
    32401 atggttacag aggtcgcatt tattggcttc ggctttgtca gcccgtacgt taagccctgc
    32461 gccgctgttg cgaatcaccg gacgtaccac cacttccatc gcgccatacg ggcaagccac
    32521 aacgcaggtt ttgcaaccaa tgcaacgttc ctgcatcaca tgaacaaacc ctttatcacg
    32581 gctgatagca ccattcgggc agacgttagc gcacggtgca tcttcacact gacggcagac
    32641 tgttgccgta gaaatgttca cacctttaat gacatggatt cgcggtaaaa aagtttccgg
    32701 ggtcagcgat gcacagtcct gattctcctg atgagaaacc acgcacgcca cttcacaggt
    32761 acggcaacca atacatttac tcgcgtcagc aatgatgaaa cggttcatca aattctccag
    32821 caatgacagt taatgcgccg atacattcac aaatcatgcc agtttttaat ttactgttat
    32881 ttaaagaaat taaattctgt aatgcaggaa aaacgatgtc atcgacacta gtgacgatga
    32941 catgtgttga caatgtttat tgcgaaagag caatgaggga gccgcggcgg atcagttttc
    33001 cgctgaaggt tttcggcggt gagaaatccc cgccatcgag cataaaaatc agccgtccaa
    33061 taatttcctg aatcatctca gttaccggaa tttttacgct ggagagcgcc ggaacggtgt
    33121 agggggcaat tgcgatatca tcgaatccga taactgacac ctgctctggc accgctacgc
    33181 cgcgctcgtg caacgctttc atcgcaccta tcgccatatc gtcgttactg gcaactaacg
    33241 cgctaaattt agccccacgt tcgagcaacg tttctacccc ttcggccccg ctggcgggcg
    33301 tccatttacc gttagcgata agtttttcat tgagcgcaat accatgctgc gccagcgcgt
    33361 ctttataccc ggcaagacgt tcaacgctgg tgggggaatc catcgagccg gtaaggaaag
    33421 caatctcctg atgtccggcg tttatcaact ctgccacggc gttaaagctg gtctgtttat
    33481 gatcgcacca gacgctatgg ctgctgtttt tgcgcaggcg gcgattaagc accattatcg
    33541 gctgactgtg tgcgtcaatg atgtcatcaa tctcatccac gcttaaaaaa cgcgggtaaa
    33601 tcataatggc gtcgcagcgc aaatccagca gatactgaat cgcctggcgc tcttcttcgg
    33661 cgctgtgttt accatctgcc aatagcaact gtcgcccttt ctcttcagcc attcgcgcgg
    33721 catgaaacag tagttcacta aaataaatgc cgtggtaaag cgtgttggtc actaccagcc
    33781 ccagcgtctg agtactcttc gccgacagat tgcgcgccag caagtttggg cggtaaccgc
    33841 tctcttctac cgcctgaaac acgcgatctt tagtctcctg gctgacgtag ccattacctg
    33901 aaagcacgcg ggaaacggtc gcttttgaaa ccccggcgcg cttcgccact tccagcatcg
    33961 tcgtcatcat tttcatccct ttacacgcaa tcaacgcagt gtactgcacc gtttgccgat
    34021 tgtccttgcg caatcggcgg gaaaaatatt caggtgaccg gtttcacaaa tataaaaaat
    34081 gaacaattaa ctctcttgct tatttagtga caactattca tgattttgtg aaaccggttt
    34141 cctaattccg tttcagcatc ggcattttcc gtcacgtcga ctgataacaa ctacatctac
    34201 cctactgata acaggataaa atccgatggc caaaaattat gcggcgctgg cacgctcggt
    34261 aatagcggca ctgggcggcg ttgataacat ctcggcagtc acgcactgta tgacgcgttt
    34321 gcgctttgtt atcaaagatg accagcttat cgacagcccg acgttgaaaa ccatccccgg
    34381 cgtgctcggc gtggtacgta gtgacaacca gtgtcaggtg attatcggca ataccgtttc
    34441 acaagccttt caggaagtcg tcagcctgct gccgggagat atgcagcccg cacagcccgt
    34501 gggtaaaccc aaactcacgc tgcgtcgcat tggtgcgggg atcctcgatg cgctgatcgg
    34561 caccatgtca ccgctgatcc cggcgattat cggcggatcg atggtcaaac tgctggcgat
    34621 gatcctcgag atgagcggcg tgctgacaaa aggatcgccg accttaacca ttctgaatgt
    34681 gattggtgac ggtgctttct tcttcctgcc gctgatggtc gcggcttctg ccgccatcaa
    34741 atttaagacc aatatgtcgc tggcgattgc catcgcgggt gtgctggtac atccgagttt
    34801 tattgaactg atggcgaaag cggcccaggg tgaacatgtc gaatttgccc tgatcccggt
    34861 caccgcggtg aaatacacct acacggtgat cccggcgctg gtgatgacct ggtgcctgtc
    34921 atatatcgaa cgctgggtgg acagcattac accggcggtg acgaaaaact tcctcaagcc
    34981 aatgctgatt gtgttgattg ccgcaccgct ggcaatcctg ctgattggcc cgattggtat
    35041 ctggatcggt agcgccattt cggcgctggt ttacaccatt catggttatc tgggctggct
    35101 ttcagtcgcc attatgggcg cgctgtggcc tctgctggta atgaccggga tgcaccgcgt
    35161 ctttacgcca accatcattc agaccattgc cgaaaccggc aaagaaggaa tggtcatgcc
    35221 gtcagagatc ggcgctaacc tgtcgctggg cggttcatca ctggcggtgg cgtggaaaac
    35281 gaaaaacccg gaactgcgcc agacggcgct cgcagcggcg gcatcagcca ttatggcggg
    35341 gatttccgaa ccggcgttat atggcgtggc gatccgcctg aaacgtccgc ttatcgccag
    35401 tcttatcagc ggttttattt gcggcgcggt tgccggtatg gcggggcttg ccagccactc
    35461 aatggcagcg ccggggctat ttaccagcgt gcagttcttc gatccggcga atccaatgag
    35521 catcgtctgg gtgttcgccg tcatggcgct ggcggtcgtg ctgtcgttca tcctcacact
    35581 gttgctcggc tttgaggata ttcctgttga ggaagcgact gccgaggtgc gaaagcatca
    35641 gagcgcacaa ccgaccgtcg ccaaagaagt aagtcttaat tgaggatgaa aatgtcagta
    35701 tttccagaag gttttttatg gggcggcgcg cttgccgcca accagtctga aggtgcgtac
    35761 cgtgaaggtg gcaaagggct gaccaccgtc gatatgatcc cacacggcga gcatcgaatg
    35821 gcggtgaaac tgggactgga aaaacgtttt cagttgcgtg atgacgagtt ttatcccagc
    35881 catgaagcga cggattttta tcatcgttat aaagaagata tcgccctgat ggcagagatg
    35941 gggttcaaag tgttccgtac ctcaattgcc tggagccgcc tctttccgca gggcgatgag
    36001 ctgacaccca accagcaggg cattgctttt tatcgcgcgg tatttgaaga gtgtaaaaag
    36061 tacggtatcg aaccgctggt cacgttatgc cacttcgatg tgccgatgca tctggtcacc
    36121 gaatatagct cctggcgtaa ccgcaagctg gtggagtttt tcagccgcta cgcccggacc
    36181 tgctttgaag catttaatgg tctggtgaaa tactggctta ccttcaatga aatcaacatt
    36241 atgttgcata gcccgttctc cggcgcgggt ctggtgtttg aagaagggga aaatcaggat
    36301 caggtgaaat atcaggccgc gcatcaccag ctggttgcca gtgcgctagc caccaaaata
    36361 gcccatgagg ttaacccgca aaatcaggtg ggctgtatgc tggcgggcgg taacttctac
    36421 ccttacagtt gcaagccgga agatgtctgg gcggcgctgg agaaagatcg ggagaacctg
    36481 tttttaatcg atgtgcaggc gcgcggcgcg tatccggctt actctgcccg cgtattccgc
    36541 gaaaaagggg taaccatcaa caaagcaccg ggcgatgatg aaatcctgaa aaacaccgtc
    36601 gattttgtct cattcagcta ttacgcctcg cgctgcgcct cggcggagat gaacgccaac
    36661 aacagcagtg cggcgaatgt agtgaaatcg ctgcgtaacc cgtatctaca ggtaagcgac
    36721 tggggctggg gtattgatcc actcggtctg cgtatcacca tgaacatgat gtacgaccgc
    36781 tatcagaagc cgctgtttct ggtggaaaac ggcctcggcg caaaagatga atttgctgcc
    36841 aacggtgaga ttaacgatga ctatcgcatc agctatttac gcgaacatat ccgcgcaatg
    36901 ggcgaagcga ttgcagatgg cattccgctg atgggctaca ccacctgggg ctgtattgat
    36961 ttggtttccg cctcaacggg tgaaatgagc aaacgctacg gttttgtcta tgtagaccgt
    37021 gacgatgcag gcaacggcac gctggcgcgc acgcgtaaga aatcgttctg gtggtataaa
    37081 aaagtgattg ccagtaatgg tgaggattta gagtaagcaa ctaccgtcgc acgaaccagg
    37141 aaagcccgat aagcgtagcg catcgggcaa tctggggttt ggcatcagtc aaaatcaaag
    37201 aaaccattcc ggcttaacac caaatcgggc tgaaagtgcc ttaatgtggg atattgtcag
    37261 ggatcgttgt ccagacaaaa tctgactgac cagggattta gagccgattt cgttcttcaa
    37321 atccgcgtag gtcagattat gttgatcaat cagcgtatga agtaacgcca cgccaaccgg
    37381 cattgctgca acggctttgt cgaactctgc aaacttttcg ttattgtttt catattctgc
    37441 aatgcggctc gccagaaagt cgataagtgg attagtatca tcttcttcaa tcaaatattc
    37501 gaccagttcc agtgcttcac gataatcatc ttctgagtca ctgcctccca gaaaggggac
    37561 tgcattgacc agttctcttg ttgctttaac agcgcgtgca gcattagcag tcattctttg
    37621 ttctctctgt agtatcgtgt cagacgccca cttttctaaa atgccaggtt tgctcggcat
    37681 cataaggcat ggtcaggaga ggtttcagcg cccgcttttg cgcgtattcg ctgtcactca
    37741 tcggcagata ttcggtaaag ctggtggcct gtgcaggcag cactaagctc aataaaaaag
    37801 cgcacatccc tgttctgatg ttcaattccc tgaattcctt actgaaaaac tactcttctt
    37861 ccaccgctaa ctgcgcgaag ccgccgttcc cttcccagcc ttccagacgt tgataaacgg
    37921 tttccaccgc atctttaatc ggctgggtca tcgggtagta aaagccgacg atatccggct
    37981 ggatgccgag gaaaatcact tcgccaatgt cttctttcaa ctggtcgata aggtagttca
    38041 gcggcatgtt atgggtagtc atcataaaca tctcggcgat atcatccggg tcgatgatgc
    38101 ggatttcgcc ggggtttagc cccatatccg tggcgtcaac aatcagcagt cgtgtagggc
    38161 gcagttcacg gatagcgacg atgtcgtttt ccggtgcgct accgccgtca atcaccaccc
    38221 agttaccttt cggtgcggcg gcgcactttt ccgccagcag cggacctgcg ccatcatcgc
    38281 ccatcatgct attgccaaca cagagtaaaa cgtcagtcac gcagtctcct caccatcaaa
    38341 tagatggcgt tttcctgatg aatatcatgc agcatactta acagcattgt actccattct
    38401 ttctgctgcg aagtttgcgc tgcccgggct ttatcgaatg cgttggccag catcggcaca
    38461 tggttaatgt cgatgacgat ctcaccatat ttcggcacgc cttccatttt gcggcgggct
    38521 tcgctgcccg cctccagagt ggcaatccat gccagatagt catcccacgg gcaggtaagt
    38581 gccgcttcca ggcaatcgat aaccccaagg tggtgaccaa tcgccaggct gtaatagacc
    38641 acctgctgcg cctcggcggg cgtggcatcg ttctcatcaa taaatttacg gctcagttga
    38701 ctgaacacca ccttttcaat catcggatac gcgcctcttc aacaacatga ttcagatggc
    38761 tgacaatctc gttcagacgc ggatcgtttt ccgcttccag ccagcgtgca acctgttctt
    38821 cgccctgccc taactgtgtc aggaagtcat cggcaatctg acgaccgtaa cgataacccg
    38881 ccaggcggcg tgcttcgcga tccactttca cgcgcagcgg ctgcaccata tcgccatgaa
    38941 ggatttccgc cggttgttca tcctgctcac ccgggccacg ggcgtgaatt ttctgctcca
    39001 gcaggccgag cgccattgca aagccgtaca gcgtggcggc tggcgttggc gggcaccccg
    39061 gaatgtagac atccaccggg acgattttat ccgtaccgcc ccacacgcag tagagatcgt
    39121 ggaaaatgcc accgctgtta ccgcaggcac cgtaggagat acagattttc gggtccggcg
    39181 cggactgcca cgcacgcagc gcaggggatc gcattgcacg ggtgaccgcg ccggtaaaca
    39241 gtaaaatatc cgcatgacgc ggtgaaggaa cgactttaat gccgaagcgt tctgcatcaa
    39301 acagcggcga aagcgtggcg aaaatttcga tttcgcagcc gttgcagccg ccgcagtcca
    39361 cgcggtaaac gtaggcagaa cgtttgattt ttttcagtaa cgacgccttc atgctggcga
    39421 tggattcatc caccgtcatc gggaccggaa tgccgttggc gtcacggggg cctaataaat
    39481 tgctcatcag atggcctctt tcatatggcg agtcagttca atacggtcgg acggcaccag
    39541 gcatttctgg cgcttacatt ccgggcaagt ctcaaagctt tcgcggtggt tttccgcgcg
    39601 gctgtcgccg ttgtgcttaa gcagcgcaat ggcgtagtcg atctctttct ggacggcgaa
    39661 aggacgattg cagacgcggc agttgcacag cgcgaagcgg gactgttgca ggaagtcttc
    39721 tttcttccac accgccagtt cgtattcttg cgacagctta atcgccgccg tcggacagac
    39781 ttcttcacag cgtccacaga agatgcagcg cccgagattg aactgccacg ccagctctcc
    39841 tgtggcgagg tcagtttcaa ccgttaaggc gtttgacggg caggcattga cgcaggccgc
    39901 acagccgatg cactgctgcg ggttctgctc tggcttacca cggaagtttt tatcaaccgc
    39961 aatcggctcc agcggataag acgaggtcgc cgtgccggtt ttgataactt ttttgataaa
    40021 ggtaaacatg gcgactcctt atttcagcgg cgagttttta cgctcaatgc tgtagcgctc
    40081 gagttctttg tacggcacca ctttgctctt cttcttacgt acatcgacca cggtcatgcg
    40141 gtcggtacag gagtagcaag ggtccaggct accgataatc aacggcgcat cggaaacggt
    40201 gttgccgcgc agcatgtagc gcagggtcgg ccagtttgcg taggtcgccg cacggcagcg
    40261 ccagcggtac agcttctggt tgtcgccggt catgctccag tggatatcgt cgccgcgcgg
    40321 cgcttcggca aagcccagcg cgaaacggtg cggaatgtag gtaaagcctt ccaccatcag
    40381 cgggccgccc ggcaggttat ccagaccgta atcgatcata ttcagcgcgg tatagacttc
    40441 gttgatacgc actttcagac gggaaataac gtcgcagccc tgctcgctgt ggacttccat
    40501 tggcagcagg ccataaccaa caaacgggtg atcggcacgg gtatcacggg cgtgaccgct
    40561 ggcacggacc atcgggccaa cgttactgaa gtcgcgagcg atttccgggt ccagacgacc
    40621 aataccgacg gtgcgttgtt ccatgttcgg tgtgctcagc agcacatcca ccagctcctg
    40681 cacttcacga cgcatctgtt gtgccagctg gcgggtctgg atcatgtcgt ctttcagcag
    40741 atcgcgacga atcccgccga tcaggttcag gccgtaggtt ttacgtgcac cggtaaggat
    40801 ctctgccatt ttcatggagg tttcacgcac gcggaagaac tgcataaagc cggagtcgaa
    40861 gccggtaaag tgacaggcga ggccgaggtt gagcagatgc gagtgcaggc gttctacctc
    40921 cagcagaatg gcgcggatca tctgcgcacg ttctggcacc tgaataccca tcgcgttttc
    40981 caccgacgtg gtgtaggcgg tgctgtgagc aaagccgcag atcccgcaca cacggtcaga
    41041 gaggaaggtc acttcgttgt aacccatgcg ggtttccgcc agtttttcca tgccgcgatg
    41101 gacatagaac aggcggtagt cggcgtcgat aatgttttcg ccatcgacga acagacggaa
    41161 gtggcccggt tcgtcagaag tgacgtgcag cggaccaatc ggcacgacat tgtttttctt
    41221 gtcgcccagt tcgttgatga actcgtaggt ttcagcatcg gtagtcggtg ccggacgctg
    41281 acgataatcc atgctgtctt tacgcagcgg ataaagttca tccggccagt catccggcag
    41341 caccagacga cgttcatccg gaagccctac cggaatcaaa ccgtacatat cgcgcacttc
    41401 gcgctcgccc cacaccgccg ccggaacgcg cggtgtcacg gacggatatt ccggtttgtt
    41461 ggcgtcaact tcgacgcgca cggttatcca gcatttggtg cccttctcca tcgacagcac
    41521 gtagtaaacg gcgtaatgac cattcagttt gcgttcgtcg ttaccaaaca gcaccgacag
    41581 ccagccaccc tgcttgtaat agagaaactc caccacttcc ggcaggtagt ttaccttcac
    41641 ggtcacggtc agctgatctt tggtctgcca ggcgtggtcc agcacgacgc ccggaaatgc
    41701 ctcattcagc gcggcgagat aatgttgacc taatttttct tcagacatgc tcaaactctc
    41761 tttaatcacg ccgccagcaa ggagacgaac gctaaaaatg caaagccaaa cccagcccag
    41821 gtaatgcgcg gagtaatatc aagacgcaga cgggccatgc tgttttcgaa cagcgcgata
    41881 accagtacgc cgaccaccag tttgacgatg gcaatcacca gtgccagcag cagcccaccg
    41941 acggtgaagg tttccatttg tccccacgga ataaacaccc cgacgaacat ctgcaacacc
    42001 accagctgtt tcaggctgat gccccatttc atgacgccaa aaccgctgcc gctgtactca
    42061 gagagcggac cttcctgcaa ctcctgctcg gcttccgcca ggtcgaacgg cagtttgccc
    42121 atttcgataa aagtggcgaa cgcacaggca caaagcgcca gcaccagcgg gatgctctgg
    42181 ctcagtggcc agtgataaac ggtgtcggtg atgttgctga tgttggtgga accggcaacc
    42241 tgtgcggcga cccacagacc aagcagcagc atcggttcaa ccaacacgcc aagcatcgct
    42301 tcacggctcg cgccgatagc ggtaaacggg ctaccggtat ccagaccaga aatggcaaag
    42361 aagaaacgcg cgatggcgaa gagatacagt aaggtgatca aatcgcccag ttgcggcagc
    42421 ggagaaccca cggtcaccac cggcagcgca gtggcgatag tcagcatgac gcccaccatc
    42481 acatacggcg tcaggcggaa cacccagccg gaggcatccg ggccaacgct ctggcgaccc
    42541 agcagtttga taatgtcgcg atactcctgc aacacgcccg gcccgcgacg gttatgcaag
    42601 cgggcgcgcg ccacgcgggt tataccggag agcagcggcg caacggcaaa taacaccagc
    42661 gcctgaatta acggatataa aacactcatt ctcaggctcc tcgtgaaaca ataatcacca
    42721 ccagcaccgc cagttcaacc agcgccatcc ggcggaacag caacgcactc ccctcgcact
    42781 gccagcccgg caccagcgac accggattca gccatttgcg tagtttcagc accggcgcaa
    42841 acgcctgttt caccggcatg gcaaaaccgt gagcggtaat caccattgat ttttcatgat
    42901 cgtagccgca cacccaggcc gcgccgcggg aacgcgacgg caaacgatcg cctttgcaaa
    42961 tcgccataat gatgaatggc agcagcgggc aggcaatcag cagcaacgtg atcatgggtt
    43021 gagaaacggt ggtgttagca ggctccagcg gcagaggtac agcagcagag agcatcggca
    43081 gtagccacgg cgcagcaaca ccgccaatta cgcagcaaat cgccagtgcc actacgctta
    43141 cgctcatcag gagcggcgca caggtggcgt tttcggcctc tttggtacgc ggcgcgccga
    43201 ggaaagtaac gccataaact ttcgccatac acatcaccgc cagcgcaccg gtaattgcca
    43261 gccccacggc aagcagcggc ccgagaagac gggcaacaaa cgcgccacta ttgctcagtt
    43321 tgaagaagga ttgatagata acccattccc cggcaaaccc gttcagcggc ggcagcgcag
    43381 ccattgccat cagcccgact aacatggcga tggagataac cggcattttc ttgccaatac
    43441 caccgagttt ttcgatatcg cgatgaccgg tacggaacca gacgctcccc gccccgagga
    43501 aaagcacgct tttgaacagg ctatggttaa gcagatggta cagaccacca accagaccaa
    43561 gggcaatcag cgccggttgt tcgagcgcga tacccgttac gccagcgccc agccccagca
    43621 ggataatgcc gatattttcc agggtgtggt aagccagcag gcgctggatg ttatgctcca
    43681 tcagcgcata cagaccaccg acgaacgcgg tgatcatacc gagcaccagc agcgcgatcc
    43741 cccaccacag cggtgcgtta ccgcccagca gtgacagggt taaaatgccc agcaggccaa
    43801 ttttcatgac taccgtagaa aacaacgcgg cagctggcgc agaggcgtta gcatgtgcct
    43861 gcggcaccca gccgtgcagc ggaataatcc ctgccagcag accaaagcca atcacaccga
    43921 gcagccagat atcggaaccg agcggcagct gttgcatacg catatccagc aggcgcagat
    43981 ccagcgtgcc gtaacgctgc cacagcagcc agcaagcaat cgccagcagc agagtgccaa
    44041 gacgtcccag agcaaaccac agtttgccct ctttgctgtt gctggtgagg aacaccgcac
    44101 acagggccat gatttcggcc attaccacga acatgccgag gttgctggcg atgacggcac
    44161 agacggcggc agccatcaac atattgatct gcaagccgtt gcacttcacc tgcgcgtggc
    44221 gatgccagtc aatgttgtag aggctgataa acagaccgca cagaccgagc gtaatcagcc
    44281 aaatcgcgtt aagcggagag atttgcacat cgtagcttac cagcgacagc gcaccgctca
    44341 cgccaaccgc gccagtcagc actgtgaagc ccgcggctgc cgtatacagg ccacccaccg
    44401 cgccgccaat tccggctatc cagccgctta gcgccttttg aaaagaaaag agaaatgcca
    44461 gaacagcggc ggcgacaaac cacgccacgc cgctattgat cagggaaatt gcgctcattt
    44521 agcctctcca ctttgagcct gctgaaacaa ggtgagatcg ccaaagtccg tgttaaaagt
    44581 cagctcacgc ttacgtttgc tgacgcgggc gatatcggtg ttatccacca gatgcagggc
    44641 tttagtcggg cacatccgca cgcaggccgg accttgttca tcaaaactac aaaggtcaca
    44701 tttgacggcg atcgcgcgaa tacctggcac ccagtcaagc aatgtgctga cacgcgccgg
    44761 agcaggcggt gccggtggcg ctttcggggt attggcgttt gccggaatat ccagcggacg
    44821 gctgccggaa aattcaattg cgccaaacgg gcaggcgatg ccgcacagtt tgcagcttac
    44881 gcacagactt tcattcaact gcacggcccc atcaacgcgg gtgatggcgt taaccgggca
    44941 aaccaccgca cagggcgcat cttcacagtg gtgacagagc tgcggcgcag attctttttc
    45001 attgagcatc actcgcaggc gcggcattga ttgcaggccg tgctggcgat gcgtctctga
    45061 acaggcggcc tcacaggtgt ggcagccgat acagagcgtg gagtcagcaa ttacaaaacg
    45121 attcaccagg cattcctcag gtgattgtca tttttgacga aaacatgccg atgaaatgtc
    45181 attttcgaca ctcatcgaca cgcccatccc caaacaggcg taacgcctgc aaaacgggca
    45241 aagcctcagc tcatgctgcc gggctttgtc cctttaccag ttggcttaaa ttcaccggca
    45301 cattgttttc aatggcggtg tataagctgt cgtaaacgcc agcgattttt tcgagatagt
    45361 gttccagaac ctgttcgcga tcgcggatgt tgaccttgcc atcaatcatg ccgtcaatgc
    45421 tcagttgcgc ctgcgcaatc cgctgtttgt cttcaccctc tttcgtttcg acgtaatact
    45481 cgatggtgtg gctgttaaag ccatccgcca gggtgacgta aatacgaaaa tgttcaaaaa
    45541 ggacgaaaca gagttctttg tccggcgcgc agctcatggc gtgatgcagg cgcgctttcg
    45601 ataacgtgat cccctgaacc agcgaattgc agtagatgtg ccactggtcc tgtaggcgac
    45661 gatgccgctg tgcgatgtaa tcggctttct cgcttatttc ccaaatagtc attgtcaggt
    45721 tacccgttta acagagatgc cagctttaag cattttttat gccaactttt aattcattgt
    45781 tattaaaacg atttttaagc taaagatgaa tttcgtcgcc gtgtcgacgt gtcatttcga
    45841 catcatcgac attattcacc gcagggataa tcaacactgg cacaattatt gcttgtagct
    45901 ggcaatagtt aatgggaggc gatatgcacg aaataaccct ctgccaacgg gcactggaat
    45961 tgatcgaaca gcaggccgca aaacacggcg caaaacgcgt aactggggtc tggctcaaaa
    46021 ttggcgcatt ttcttgtgtc gaaaccagct ctcttgcctt ttgttttgat ctggtttgcc
    46081 gcggcagcgt ggcggaaggt tgtaaactgc acctcgaaga acaagaggcc gaatgctggt
    46141 gtgaaacatg ccaacagtat gtgacgctac tgacccagcg cgtccgccgc tgtccacagt
    46201 gtcatggcga catgctacaa attgtggcag acgacggttt acagattcgg cggatagaaa
    46261 tagaccagga gtgagcgatg tgtacaacat gcggttgcgg tgaaggcaac ctgtatatcg
    46321 agggtgatga acataaccct cattccgcgt ttcgtagcgc gccatttgcc ccggcggcac
    46381 gcccgaagat gaaaatcacc ggcattaaaa cgcctgaatt tacccccagc cagactgaag
    46441 aaggcgacct gcattacggt catggcgaag cgggcactca cgcgccgggc atgagccagc
    46501 gtcggatgct ggaagtcgaa attgacgtgc tggacaaaaa taaccgtctg gctgaacgca
    46561 accgcgcgcg ctttgctgcc cgcaagcaac tggtgctcaa cctggtttcc agccctggtt
    46621 ccggtaaaac caccctgctg acggaaacct taatgcgcct gaaagacagc gttccgtgcg
    46681 cggttattga aggcgatcag caaaccgtga acgatgccgc acgcattcgt gctaccggca
    46741 caccagcgat tcaggtgaat accggtaaag gctgccatct cgacgctcag atgattgccg
    46801 acgccgcacc gcgcctgcca ctggacgata acggtattct gtttatcgaa aacgttggca
    46861 acctggtatg cccggccagc ttcgatctcg gtgaaaaaca caaagtggcg gtgctttccg
    46921 ttaccgaagg tgaagacaaa ccgctgaaat atccgcacat gtttgccgcc gcctcgctga
    46981 tgctgctcaa caaagttgac ttgctgccgt atctcaattt cgacgttgag aagtgcatcg
    47041 cctgcgcccg tgaagtcaat ccagaaattg aaatcatcct tatttccgcc accagcggcg
    47101 aagggatgga ccagtggctg aactggctgg agacacagcg atgtgcatag gcgttcccgg
    47161 ccagatccgc accattgacg gcaaccaggc gaaagtcgac gtctgcggca ttcagcgcga
    47221 tgtcgattta acgttagtcg gcagctacga tgaaaacggt cagccacgcg taggccagtg
    47281 ggtactggtt cacgttggct ttgccatgag cgtaattaat gaagccgaag cgcgcgacac
    47341 tctcgacgcc ttacaaaaca tgtttgacgt tgagccggat gtcggtgcgc tgttgtatgg
    47401 cgaggaaaaa taatgcgttt tgttgatgaa tatcgcgcgc cggaacaggt gatgcagtta
    47461 attgagcatc tgcgcgaacg tgcttcacat ctctcttaca ccgccgaacg ccctctgcgg
    47521 attatggaag tgtgtggcgg tcatacccac gccattttta aattcggcct cgaccagttg
    47581 ctgccggaaa acgttgagtt tatccacggt cccggttgcc cggtgtgtgt actgccgatg
    47641 ggtagaatcg acacctgcgt ggagattgcc agccatccgg aagtcatctt ctgtaccttt
    47701 ggcgacgcca tgcgcgtacc agggaaacag ggttcgctgt tacaggcaaa agcgcgcggt
    47761 gccgatgtgc gcatcgttta ctcgccgatg gatgcgttga aactggcgca ggagaatcca
    47821 acccgcaaag tggtgttctt cggcttaggt tttgaaacca ccatgccgac caccgccatc
    47881 actctgcaac aggcaaaagc ccgcgatgtg cagaattttt acttcttctg ccagcacatt
    47941 acgctcatcc caacactgcg cagtttgctg gaacagccgg ataacggtat cgacgcgttc
    48001 ctcgcgcccg gccacgtcag tatggtgatt ggcactgatg cctataattt tatcgccagc
    48061 gattttcatc gtccgctggt ggtggctggt ttcgaaccgc ttgatctact gcaaggcgtg
    48121 gtcatgctgg tggagcagaa aatagcggcc cacagcaagg tagagaatca gtatcgtcgg
    48181 gtggtgccgg atgccggtaa cctgctggcg caacaggcga ttgccgatgt gttctgtgtc
    48241 aacggcgaca gcgaatggcg cggcttaggc gtgattgaat cttctggtgt acacctgacg
    48301 ccggattatc aacgattcga tgccgaagcg catttccgcc cggcaccgca gcaggtctgc
    48361 gatgacccgc gcgcacgttg tggagaagta ttaacgggca aatgtaagcc gcatcaatgc
    48421 ccgctgtttg gtaacacctg taatcctcaa accgcgtttg gtgcgctgat ggtttcctcc
    48481 gaaggagcgt gcgccgcgtg gtatcagtat cgtcagcagg agagtgaagc gtgaataata
    48541 tccaactcgc ccacggtagc ggcggccagg cgatgcagca attaatcaac agcctgttta
    48601 tggaagcctt tgccaacccg tggctggcag agcaggaaga tcaggcccgt cttgatctgg
    48661 cgcagctggt agcggaaggc gaccgtctgg cgttctccac cgacagctac gtcatcgacc
    48721 cgctgttctt tcctggtggc aatatcggca agttggcgat ttgcggcacc gcgaacgacg
    48781 tagcggtcag tggcgctatt ccgcgttatc tctcctgtgg atttatcctt gaagaaggat
    48841 taccgatgga gacgctgaaa gccgttgtga ccagcatggc agaaaccgcc cgcgcggcag
    48901 gcattgccat cgttactggc gacactaaag tggtgcagcg cggcgcggca gataaactgt
    48961 ttatcaacac cgctggtatg ggcgcaattc cggcgaatat tcactggggc gcacagacgc
    49021 taaccgcagg cgatgtattg ctggttagcg gtacactcgg cgaccacggg gcgactatcc
    49081 ttaacctgcg tgagcagctg gggctggatg gcgaactggt cagcgactgt gcggtactaa
    49141 cgccgcttat tcagacgctg cgtgacattc cctgcgtgaa agcgctgcgt gatgccaccc
    49201 gtggtggtgt aaacgcggtg gtacatgagt tcgcggaagc ctgcggttgt ggtattgaaa
    49261 tttcagaagc ggcactgccg gttaaacctg ctgtgcgcgg cgtttgcgaa ctgctgggac
    49321 tggacgccct taactttgcc aacgaaggca aactggtgat cgccgttgaa cgcaacgcgg
    49381 cagagcaagt gctggcagcg ttacattccc atccactggg aaaagacgcg gcgctgattg
    49441 gtgaagtggt ggaacgtaaa ggtgttcgtc ttgccggtct atatggcgtg aaacgaaccc
    49501 tcgatttacc acacgccgaa ccgcttccgc gtatatgcta ataaaattct aaatctccta
    49561 tagttagtca atgacctttt gcaccgcttt gcggtgcttt cctggaagaa caaaatgtca
    49621 tatacaccga tgagtgatct cggacaacaa gggttgttcg acatcactcg gacactattg
    49681 cagcagcccg atctggcctc gctgtgtgag gctctttcgc aactggtaaa gcgttctgcg
    49741 ctcgccgaca acgcggctat tgtgttgtgg caagcgcaga ctcaacgtgc gtcttattac
    49801 gcgtcgcgtg aaaaagacac ccccattaaa tatgaagacg aaactgttct ggcacacggt
    49861 ccggtacgca gcattttgtc gcgccctgat acgctgcatt gcagttacga agaattttgt
    49921 gaaacctggc cgcagctggc cgcaggtggg ctatacccca aatttggtca ctattgcctg
    49981 atgccactgg cggcggaagg gcatattttt ggtggctgtg aatttattcg ttatgacgat
    50041 cgcccgtgga gtgaaaaaga gttcaatcgc ctgcaaacat ttacgcagat cgtttctgtc
    50101 gtcaccgaac aaatccagag ccgcgtcgtt aacaatgtcg actatgagtt gttatgccgg
    50161 gaacgcgata acttccgcat cctggtcgcc atcaccaacg cggtgctttc ccgcctggat
    50221 atggacgaac tggtcagcga agtcgccaaa gaaatccatt actatttcga cattgacgat
    50281 atcagcattg tcttacgcag ccaccgtaaa aacaaactca acatctactc cactcactat
    50341 cttgataaac agcatcccgc ccacgaacag agcgaagtcg atgaagccgg aaccctcacc
    50401 gaacgcgtct tcaaaagtaa agagatgctg ttgattaatc tccacgagcg ggacgattta
    50461 gccccctatg aacgcatgtt gttcgacacc tggggcaacc agattcaaac cttgtgcctg
    50521 ttaccgctga tgtctggcga caccatgctg ggcgtgctga aactggcgca atgcgaagag
    50581 aaagtattta ccactaccaa tctgagctta ctgcgccaga ttgccgaacg tgtggcaatc
    50641 gctgtcgata acgccctcgc ctatcaggaa attcatcgtc tgaaagaacg gctggttgat
    50701 gaaaacctcg ccctgaccga gcagctcaac aatgttgata gtgaatttgg cgagattatt
    50761 ggccgcagcg aagccatgta cagcgtactt aaacaagttg aaatggtggc gcaaagtgac
    50821 agtaccgtgc tgatcctcgg tgaaactggt acaggtaaag agctgattgc ccgcgcgatc
    50881 cataatctca gtgggcgtaa taatcgccgc atggtcaaaa tgaactgcgc ggcgatgcct
    50941 gccggattgc tggagagcga tctatttggt catgagcgtg gggcttttac cggtgccagc
    51001 gctcagcgca ttggtcgttt tgaactggcg gataaaagct cactattcct cgatgaagtg
    51061 ggcgatatgc cgctggagtt acagccgaag ttgctgcgtg tattacagga acaggagttt
    51121 gaacgtcttg gcagcaacaa aatcattcag acggacgtac gtttaattgc cgcgactaac
    51181 cgcgatctga aaaaaatggt cgcagaccga gagttccgta gcgatctcta ttaccgcctg
    51241 aacgtattcc cgatccacct gccgccacta cgcgagcgtc cggaagatat tccgctgctg
    51301 gcgaaagcct ttaccttcaa aattgcccgt cgtctggggc gcaatatcga cagcattcct
    51361 gccgagacgc tgcgcatcct gagcaacatg gaatggccgg gcaacgtgcg tgagctggaa
    51421 aacgtcattg agcgcgcggt attgctaaca cgcggcaacg tgctgcagct gtcattgcca
    51481 gatattgctt taccagaacc tgaaacgccg cctgccgcaa cggttgtcgc ccaggagggc
    51541 gaagatgaat atcagttgat tgttcgcgtg ctgaaagaaa ccaacggcgt ggttgccggg
    51601 cctaaaggcg ctgcgcaacg tctggggctg aaacgcacga ctctgctgtc acggatgaag
    51661 cgactgggaa ttgataaatc ggcattgatt taacagatgt ggttatactc gatcaacatt
    51721 caatgaaagg aggcagtatg gcagtttcag caagaaatca attaaccgga acagttagcg
    51781 cagtagcaat gggcgctgtg aatgatgaag tagaactgac gctggcaggt ggtgcaaaac
    51841 tggtggcaat tgttacacac agcagccagc aggctcttgg tctggcaaaa gggaaagaag
    51901 cgattgccct gattaaagcc ccgtgggtaa cactggcaac ggaagactgt ggactgaaat
    51961 tctctgctcg caaccagttt gctggcagcg tgtcgacaat caccgaaggc gcagtgaacg
    52021 ccactgtcca tatcaaaacg gatgcgggtt ttgaaattgt ggcagtggta acaaatgaaa
    52081 gtcaggatga aatgaaactc accactggct cgcgcgttat tgcattgatc aaagcatcag
    52141 ccatcctgat tgccaccaaa gcgtaaacgc cttatttgcc ggagagtatg gctctccggc
    52201 agatttattt ctttggacga tatttttctg gcaactccgg caccggacgc ttgtcatcga
    52261 tgagatgacg cacggttaag atcggatgac gccacagcat tcgcggcccg gcccaacgca
    52321 taatctgttt catctcttca cgctttgctg gctggtaaca gtgcaccgga cactgcttac
    52381 aggctggttt ctcttcgccg aacacacatt tatccagccg cttttgcgcg taggcaaaca
    52441 gcgcgtcgta atgctccggc tccgctgacg cctgcgggca tttcgcttga taaagatcga
    52501 tcattttttt aatcgtcagt ttttcacgag agatacgctt gccggacatg ctgcctccat
    52561 actcttaagg tgtatttata ttacaactta atttgaaagg ggactatggc tctgaaggag
    52621 gaggtttatt caaccgacgc aattttgcgt acttgcttca taagcatcac gcaaaagctg
    52681 caaaacagca tctttcccgg aatcaccatc aagaactcgc cgttcgcttc ttcccctgaa
    52741 atgattaact ccggtatcat gtgcgcctta tgtgataaca acgaaaataa aaaccatcac
    52801 accccattta atatcaggga accggacata accccatgag tgcaatagaa aatttcgatg
    52861 cccatacgcc catgatgcag cagtatctca agctgaaagc ccagcatccc gagatcctgc
    52921 tgttttaccg gatgggcgac ttttatgaac tgttttatga cgacgcaaaa cgggcgtcgc
    52981 aactgctgga tatttcactg accaaacgcg gtgcttcagc gggagagcca atcccgatgg
    53041 cggggattcc ctaccatgcg gtggaaaact acctcgccaa actggtgaac cagggcgaat
    53101 cggttgctat ttgtgaacag attggcgatc cggcgaccag caaagggccg gtcgagcgca
    53161 aagttgtccg tatcgttacg ccgggcacca tcagcgatga agcgctgttg caggaacgtc
    53221 aggacaacct gctggcggct atctggcagg acagtaaagg tttcggctac gcaacgctgg
    53281 atatcagttc cggtcgtttt cgcctgagcg aaccggcgga ccgcgaaacg atggcggcag
    53341 aactgcaacg tacgaatcca gcggaattac tgtatgcgga agatttcgcc gagatgtcgc
    53401 tgattgaagg tcgccgcggc ctgcgtcgtc gcccgctgtg ggagtttgaa atcgacaccg
    53461 cgcgccagca gttaaacttg caatttggca ctcgcgatct ggtcggtttt ggcgtcgaga
    53521 acgcgccgcg cggactttgt gccgccggtt gtctgttgca atatgcgaaa gatacccaac
    53581 gcacgaccct gccgcatatt cgttctatca ctatggaacg tgagcaggac agcatcatta
    53641 tggatgccgc gacgcgtcgt aacctggaaa tcacccagaa tctggcgggt ggtgcggaaa
    53701 atacgctggc ttctgtgctc gactgcaccg tcacgccgat gggcagccgt atgctgaaac
    53761 gctggctgca tatgccagtg cgcgataccc gcgtcttgct tgagcgccag caaactattg
    53821 gcgcattgca ggatttcacc gccgagctgc agccggtact gcgtcaggtc ggcgacctgg
    53881 aacgtattct ggcgcgtctg gctttacgaa ccgctcgccc acgcgatctg gcccgtatgc
    53941 gtcacgcttt ccagcaactg ccggagctgc gtgcactatt agaaaatgtc gaaagcgcac
    54001 cggtacaggc gctgcgtgag aagatgggcg agtttgccga actgcgcgat ctgctggagc
    54061 gggccattat cgacacaccg ccggtactgg tgcgcgacgg tggtgttatc gcgccgggct
    54121 ataacgaaga gctggatgag tggcgggcgc tggctgacgg cgcgaccgat tatctggagc
    54181 gtctggaaat ccgcgagcgt gaacgtaccg gcctggacac gctgaaagtc ggctttaacg
    54241 cggttcatgg ttattacatt cagatcagcc gtggacaaag ccatctggca cccatcaact
    54301 atatgcgtcg ccagacgctg aaaaacgccg aacgctacat tattccagag ctaaaagagt
    54361 atgaagacaa agtactcacc tcgaaaggta aagcactggc actggaaaaa cagctttatg
    54421 aagagttgtt cgacctgctg ttgccgcatc tggaagcgtt gcaacagagc gcgagcgcgc
    54481 tggcggaact cgacgtgctg gtgaacctgg cggaacgggc ctataccctg aactacacct
    54541 gcccgacctt tattgataaa cctggcattc gcattaccga aggccgccat ccagtggttg
    54601 aacaggtact gaacgaaccg tttatcgcta acccgctaaa cctgtcgcca cagcgccgca
    54661 tgttgatcat taccggtccg aacatgggcg gtaaaagtac ctatatgcgc cagaccgcgt
    54721 tgattgcgct gatggcgtat atcggcagct acgtaccggc gcaaaaagtc gagattggcc
    54781 cgatcgaccg tatctttacc cgcgtaggcg cggcagacga tctggcatcc gggcgttcaa
    54841 cctttatggt ggagatgacc gaaaccgcca atattttaca taacgccacc gaatatagtc
    54901 tggtgttgat ggatgagatc gggcgtggaa cgtccactta cgatggtctg tcgctggcgt
    54961 gggcatgcgc ggaaaatctg gcaaataaga tcaaagcgtt gacgctgttt gctacccact
    55021 atttcgagct gacccagtta ccggagaaaa tggaaggcgt cgccaacgtg catctcgatg
    55081 cgctggagca cggcgacacc attgccttta tgcacagcgt gcaggatggc gcggcgagca
    55141 aaagctacgg cctggcggtt gcagctctgg caggcgtgcc aaaagaggtt attaagcgcg
    55201 cacggcaaaa actgcgtgag ctggaaagca tttcgccgaa cgccgccgct acacaggttg
    55261 atggtacgca gatgtccctg ctttctgcgc cagaagaaac gtcgcctgcg gtcgaggcac
    55321 tggaaaacct cgacccggat tcactgactc cgcgtcaggc gctggagtgg atttatcggt
    55381 tgaagagtct ggtgtaataa caattcccga tagtcttttg ctatcgggaa tattaacgac
    55441 aactgacgaa tcaaataaaa ataccctgta taataggaaa tcttatttta cagggtaaaa
    55501 ccatgccatc tacacgctat caaaaaatta atgcccatca ctatcgttat atatgggccg
    55561 ttggtgatat tcatggtgac tatcaattat tacaatcccg cttacatcaa ctctcttttt
    55621 gccctgaaac cgacttactt atttccacag gcgataatat tgatcgtggg ccgaagagtc
    55681 ttaacgtgct gcacctgcta aaccaaccct ggtttacgtc ggttaaaggc aaccacgaag
    55741 cgatggcgtt ggatgcattc gaaactggcg atggaaatat gtggcttgcc agcggtggtg
    55801 actggttttt cgatttaaat gattcagagc aacaagcggc aatagatctg ttgctgaaat
    55861 tccatcacct tccacatatt attgaagtta ctaacgacaa cacaaaatat gtcatcacac
    55921 atgcagatta tccggggaat gaatatctct ttggtaaaga aatagcggag agcgaattac
    55981 tctggcctgt tgatcgtgtg cagaaatcgc ttaatggcga gttacaacaa ataaacggcg
    56041 ctgattattt tatatttgga catatggtgt ttgataacat tcagacgttc gcaaaccaga
    56101 tttatattga taccggatcg ccgaaaagcg ggcggctgtc attttataaa ataaagtaat
    56161 gaggccgggt aaagcaaagc cactacccgg cactttttat taacgcttat ctgccgccag
    56221 cagcggcggg atgctcggca ccatcggcgc gtcatcaata tctttctgcg tcatgcggaa
    56281 cgcttcaggg taatgttcgc ggctggtgcg gcgcagcggt tcagtatcgc gccaggtata
    56341 aaggcaatgc tggcactgat ataccgtcca gacatctttc actggcgatt tcgccatcac
    56401 ttcaatctgt tcatcggcac aacgtggaca aatcatcttg ttctccttat ttacgtgcgg
    56461 ccagcatagc ggtcagtttt tcagcccagg ctttggtttc cggtaaatcc accaccggct
    56521 ggctgtagtg accacggttg tccggggcga caggcgtggt ggcgtcgata atcagcttgt
    56581 cggtgatccc cgccgggctt gagccggggt cgagttccag cacggacata ttcggcaact
    56641 gtaccaggtc ccctgccggg ttcactttcg acgaaagcgc ccacatcacc tgcggcaggt
    56701 tgaacggatc aacatcttca tcgaccataa tcaccatctt cacgtagccc agtccgtgtg
    56761 gtgtggtcat cgcacgcagg cctactgcgc gggcaaaacc gccgtagcgt tttttggtgg
    56821 agataatcgc caacaggccg tgggtgtaca tggcgttcac cgcctgcact tccgggaact
    56881 cggctttcag ttgctgatac agcggcacac aggtggctgg ccccatcagg tagtcgattt
    56941 ccgtccacgg catcccgaga tagagcgatt caaaaatggg tttgctgcga taagagactt
    57001 tatcgatgcg caccacggtc atgttacgcc cgccggagta gtgcccggta aactcaccga
    57061 acggcccttc gatttcgcgt ttacggcttt cgatgacccc ttcgaggatc acttctgaac
    57121 cccacggcac atcaaaaccg gtcagcgggg cggtggcgat cgggtacgga ctttcacgca
    57181 gcgcgcctgc catttcatac tcagactgat cgtatttcaa cggcgtggcc cccatcagcg
    57241 tgatgatcgg atcgttaccg agcgtgatcg caatcggcag atcttcaccg cgctcttctg
    57301 ctttatgcag atgcagggcg atatcgtgca tcggcaccgg ttgcagaccg agcttacgct
    57361 tacccttcac ttccatacga tagataccga cgttctgctt gccgaagtta tccgggtcga
    57421 gcggatcgcg ggaaaccacg caggctttgt cgagatagaa accgccatcg ccatcgttta
    57481 aacgaaacag cggcagaata tcgaacagat tgatctcatc tccatcgacg gtgttctgcg
    57541 cccaggctgg attggcgcgg cgttccgggg ctatcgggaa gttatcccag cggcggataa
    57601 actcatcaat ctgtttttta accggggtat ttggcggcaa gccgagagaa atcgcgtggt
    57661 tctgccagga accgatggtg ttcatcgcca cgcgcgcatc ggtaaagccg cgaatattgt
    57721 caaaccacag cgcgggcgcg ccgtcgccga tacgcccggt ggcgttagct gctgctgcca
    57781 gatccggttc cgcgttcacc tcttcgctga ttttcagcaa ttgcccatgg tcgtcgagcg
    57841 cctgtaaaaa gctgcgtaaa tcatcaaatg ccattattca ttctcctgag aaaaattccg
    57901 ggcctgcggc aatccttgcc agcgcctggc gtgaggatgt tcgaggccaa attgatccag
    57961 cacgcgggct accacgtgct ggacaatgtc atctaccgtt tcgggatggt tataaaaggc
    58021 aggcatcggc ggcaccatcg ccacgcccat gcgcgaaagt gcgagcatat tttcgagatg
    58081 gatggtgcta agcggcattt cacgcggcac cagcaccagt ttgcggcctt ctttgagcac
    58141 gacgtccgcc gcgcgcccta ccaggccatc ggcgtaacca gcgcggatac cggcgagcgt
    58201 tttcatactg cacggaataa cgatcatgcc gtcggtacga aaggaacctg aggagatggt
    58261 tgcggcctga tccgccgggt tatggcagaa gtctgcgagg gcagcaacat cgcgggcgtt
    58321 gtaaggcgtt tccagttcaa tggtggtttt cgcccacttc gacatcacca gatgagtctc
    58381 gacattcggc atctcccgca gcgcttgcag taatgccaca cctaagaggc gcaccggtag
    58441 cccctgtcat cccgacgatc agtttcattg cttactctct taattgttcg tatacgaacg
    58501 ttattattaa catactcctt catttccaca gcggcaagga ttgaaaagta acaacatctt
    58561 cttcgtcact gaaaaaccgc tatgatagcg acagagaatt agcccggagt ttacatggcg
    58621 ttacgaaata aagcgttcca tcagttacga cagctttttc agcagcatac ggcccgctgg
    58681 cagcacgagt tacctgacct gaccaaacca cagtacgcgg tgatgcgcgc cattgctgat
    58741 aagcctggta tcgaacaggt ggcactgata gaagcagcag tcagcaccaa agcaacgctg
    58801 gcagaaatgt tggcaagaat ggaaaatcgt ggcttagtca gacgtgaaca tgacgccgct
    58861 gataagcggc gacgctttgt ctggctgact gccgaaggag aaaaggtact tgctgcggcg
    58921 ataccgattg gcgacagtgt ggatgaggaa tttttggggc gtttgagtgg agaagagcag
    58981 gagctgttta tgcagctggt gcgcaagatg atgagcaaat aggatgttga ttgccggatg
    59041 ggacgctgac gtgtcttatc caggcgacga aacacaccaa ctccccatac aaaagaaaaa
    59101 ggccagcctc ataagagact ggcctttatg acagatgctt acttattcgc ggaacagcgc
    59161 ttcgatattc agcccctgcg tttgcaggat ttcgcgcaaa cggcgcaggc cttcaacctg
    59221 aatctggcga acacgttcac gggtgaggcc aatttcacga cctacatctt ccagtgttgc
    59281 cgcttcgtac cccagcaaac cgaatcgacg tgccagtact tcacgctgtt tggcgttcag
    59341 ctcgaacagc catttgacga tgctctgctt catatcgtca tcttgcgtgg tatcttccgg
    59401 accgttctct ttttcatcgg ccaggatgtc cagcaacgct ttttcggaat caccacccag
    59461 cggggtgtct accgaggtaa tgcgctcgtt aagacgaagc atacggctga cgtcatcaac
    59521 tggcttatcc agttgctctg cgatctcttc cgcacttggt tcatggtcca gtttatggga
    59581 caactcgcgt gcggttcgca ggtaaacgtt cagctccttt acgatgtgaa tcggcaaacg
    59641 aatagtacgg gtttggttca taatcgcccg ttcgatcgtc tggcgaatcc accaggttgc
    59701 gtatgttgag aagcggaaac cacgttccgg gtcaaacttc tctaccgcgc ggatcagccc
    59761 caggttgccc tcttcgataa gatccagcaa agccagacca cgattgccat aacggcgggc
    59821 aatttttacc accagacgca agttactctc gatcatccgg cggcgagagg caacatctcc
    59881 acgcagtgcg cgacgcgcaa aataaacttc ttcttcggcc gttaacagtg gtgaataacc
    59941 aatctcacca aggtaaagct gagtcgcgtc cagcacacgc tgtgtggctc cctgcgataa
    60001 cagttcctct tcggccaaat cgttatcact gggttcctct tctactaagg ccttttcgtc
    60061 aaaaacctca actccgttct catcaaattc cgcatcttca tttaaatcat gaactttcag
    60121 cgtattctga ctcataaggt ggctcctacc cgtgatccct tgacggaaca ttcaagcaaa
    60181 agcctggttc cgccgattta tcgctgcggc aaataacgca gcgggtttac ggatttcccc
    60241 ttgtaacgaa tttcaaaatg caagcgtgtt gaactggttc cggtgctacc catggttgct
    60301 attttttgcc ccgccttcac ttcttgttgt tcccggacca gcattgtgtc gttatgggcg
    60361 taggcactca ggtaatcatc attatgtttg atgataatca gattaccgta gccgcgcagc
    60421 gcgttaccgg cataaacaac gcggccatct gcagtcgcga taattgcctg tcctttgctg
    60481 cctgcgatat caatcccctt gttgcccccc tcagaagcgc caaaggtttc gatcactttg
    60541 ccctcagtcg gccagcgcca ggtggagata ggcgtactgg ttgatgtact gctgacagtc
    60601 ggctcggttg tgcttgctgt tggtaccgtt acaggcgctg tgaccgtggt cgcagttggc
    60661 ttgttgttcg gcaacatttt gttagcactc tgttcacccg aagactcaga atacgtaatt
    60721 gtcggttgcg aagcaacagc aacggtggaa ttttgtgcag gcttgatcac aactccttgc
    60781 tctgctgcgt cggcctgggt aatggcattt ccgccagtga ttggcgtacc ggaagcattc
    60841 cccacctgta aggtctgacc gacgttcagc gcatatggtg cctgaatatt gttgcgctga
    60901 gcaaggtcac ggaaatcgtt gccagtaatc caggcgatat agaaaagtgt gtcgcctttt
    60961 ttcacggtgt atgtactgcc gctataactg cctttcggaa tgttcccata ctgacggttg
    61021 tagacgattc gtccgttttc catctgtacc ggctgctgag ctactggctg cacaggctgg
    61081 atttgcggtt gttgagtagc ctgaatttgt ggctgctgta ccggctgaat ttgcggttgc
    61141 tgcgctgtag acgtcgtccc cattttcgac ggcggcgtaa tcaacatacc agaattggta
    61201 tttgtaggcg cattgccatt aacggagctg accggtgccg gtggatttga agtgtcagaa
    61261 cagcctgcca gccatagcga aaccagtgac aaagccgcaa tgcggcgaac ggtgaatttt
    61321 gggcttcccg cgctcattta tcccccagga aaaattggtt aataaccagt gacataatta
    61381 ccgtgcaagg caccatactg aacactggaa aagatgttca cgatacgctg acttgcggca
    61441 aaataaccag gaaaaatcca ggtatttcct cacgttttaa gccagctcac ccttcactaa
    61501 agggacaaag cgcacggcct ccacggtatc gataataaat tcgcctcccc gacgacgcac
    61561 ccgtttcaaa tactggtgct cctcccctac gggtaagacg agaatcccgc cttcgtccag
    61621 ctgcgtcatt agcgcagttg gaatttccgg cggtgccgcc gtaacaatga tagcgtcaaa
    61681 cggcgcacgt gcctgccaac cttgccatcc atcgccatga cgggttgaaa cattatgtaa
    61741 atcaagattt ttcaggcggc gacgtgcctg ccactgcaag cctttaatcc gttcaaccga
    61801 gcaaacatgc tggacaagat gcgccaggat tgccgtttga tatcccgaac cagtgccaat
    61861 ttccagcacc cgcgactgcg gcgtcagctc gagtaattcg gtcattcgcg ccaccatata
    61921 cggctgcgaa attgtctgcc cctgacctat cggcaaggcg atattgtccc aggctttttg
    61981 ttcaaacgct tcatcaacga atttttcacg cggcacggcg gcaagtgcat tcagcacctg
    62041 ctcatcctga ataccttgcg cacgtaattg atccagaagt gcttgtacgc gtctgcttac
    62101 cattgcgtgc caactcccac gctgtttaac cagtctgaaa ccacatcttg cgcgctatgc
    62161 gcagttaaat ccacatgcag cggcgtgatg gagacatagc cctcatctac cgcagcaaaa
    62221 tcggtccccg gaccggcatc acatttaccg cccggcgggc caatccagta cagcgtattg
    62281 ccgcgcggat cttgctgcgg gatcacctga tctgccggat gtcgtgtacc gcagcgcgtc
    62341 acgcgaatac ctttgatttg atccaatggt aaatccggaa cgttaatgtt aagaatacgt
    62401 ccggtgcgca gcggctcttt acacagtgcg cgcaaaattg aacaggttac cgccgcggca
    62461 gtgtcgtaat gtttatgccc gtcaagcgag acggcaagcg ccggaaaacc taaatgacgg
    62521 ccttccatcg cggcggctac cgtaccggaa taaataacat catcccccag attcggcccg
    62581 gcgttaattc cggacacaac aatgtccggg cgcggacgca tcagagcatt cacgccaaga
    62641 tagacgcaat cggtcggggt tcccatttgc acagcaatat caccattttc aaaggtaaac
    62701 gtgcgcaggg aggattccag tgtcagagaa tttgaagcgc cgctgcggtt acgatcgggg
    62761 gcgaccacct gaacgtcagc aaactcacgc aaggctttcg ccagcgtttg tataccgggt
    62821 gcatgtaccc cgtcatcatt actcagcaat atgcgcataa tcacctgttg tgttgataag
    62881 ttccctgaca acgctggttg caaaactacc cgccggaagc cagaaacgga tttctacggt
    62941 gacgtcatcc caccagttcc agcttaattg ttgcggatac agcagcatcg ctctgcgcgc
    63001 ggcttcaact ttttcgcgca ccagtaaggc ttgtaattca gtttctgcgg cgacagctgc
    63061 ttgttcgaat gccagcgctt cacgctgagt tccccattcg ccactgcccg gcaatgcggc
    63121 ggttatcatc agctctttat cgttgacgcg acgctgtaat tccaccagtt cttcggtggt
    63181 tgcgacaaac cagctaccac gtccggctaa ttgtagcgca tcgccgtcaa caacttgatt
    63241 aacgtctgct tttttgaggc gctcagcaac aatctgatta aacaacgcac tgcgggctgc
    63301 cgacaaccaa aaactccgtt tattgcgatc gcgcaccgga gtattggttt gcgcccagcg
    63361 cagcgcgccc tgcaagttgc taccgccaat cccaaaacgt tgggcaccga agtagttcgg
    63421 tacacctttt acgcaaatat cgatcagacg ttgttcaacg tcatcgcgat tgctcacttc
    63481 gcgcagaacc agggtaaagg cgttaccttt cagcgcgcct aaacgcagct tgcgcttgtg
    63541 ccgcgcatac tccagcacct ggcagccttc cagttgaaag gcgctcagat cgggcatctc
    63601 tttgcccggc acgcgagcgc ataaccactg ttccgtaaca gcatgtttgt ctttttgccc
    63661 agcgaagctg acttcacggg aatgaatttt caggaatttc gccagtgcat ccgccacaaa
    63721 acgggtattg cagccgtttt tgaggattct aaccagaata tgctcacctt caccatcagg
    63781 ctcaaagccc aaatcttcca ccaccacaaa gtcttccgga ttggctttca gcagcccggt
    63841 gccttgcggt ttaccgtgga ggtaagtgag attatcaaac tcaatcattt tgttgcctta
    63901 atgagtagcg ccaccgcttc acaggcaatc ccttccccac gtccggtaaa tccaagtttt
    63961 tccgtagtag tggctttcac gttaacatca tccatatggc agccgagatc ttcggcaata
    64021 aacacgcgca tttgtggaat gtgcggcaac atcttcggtg cctgagcgat gatagtgaca
    64081 tcgacgttgc caagggtata acccttcgcc tgaatacgac gccaggcttc gcgtagcagc
    64141 tcgcggctgt cggcaccttt aaatgccgga tcggtatccg ggaacagttt gccgatatcc
    64201 cccagcgccg ccgcgccaag caatgcatcg gtcaacgcat ggagcgccac atcgccatca
    64261 gaatgcgcca gcaatccttt ttcgtaagga atgcgtacgc caccaatgat aattgggcct
    64321 tcaccgccaa aggcgtgtac gtcaaaaccg tgtccaattc gcattatgta ttctcctgat
    64381 ggatggttcg ggtgaggtaa aactcggcca gtgccaaatc ttccgggcgc gtgactttaa
    64441 tgttatccgc gcggccttcg accaactgcg gatgaaatcc gcaatattcc agcgccgagg
    64501 cttcgtcggt aatggtagcg ccttcattta gagcgcgcgt caggcagtca tgtaacagct
    64561 cacgagggaa aaattgcggc gtcagcgcgt gccataagcc gttgcgatca acggtatgag
    64621 caatggcatt tttgcccggt tcggcacgtt tcatcgtatc gcgcactggt gcggcgagga
    64681 tcccccccgt gcggctggtt tcgctcaacg ccaacaggcg cgcgaggtca tcctgatgca
    64741 gacaaggacg agcggcatca tgcaccaata cccactgcgc gtcgccagcg gctttcaaac
    64801 ctgccagcac ggaatcggca cgctcatcac cgccatctac aacggtgatt tgcggatgat
    64861 tcgccagagg aagttgtgca aaacggctat cgccaggact tatggcaatg acgacatgtt
    64921 tcacccgggg atgcgccagc agcgcatgca ccgagtgttc aagaatggtt tgattaccga
    64981 ttgagagata ttgcttagga cattccgttt gcattcgacg gccaaatccg gccgccggaa
    65041 ccacggcgca aacatccaaa tgagtggttg ccatgttaat tcctgggctg atttatcgat
    65101 tgttttgccc cgcagactgt gcgcgcttcg acgcgtcagg caccagacga taaaaagttt
    65161 cgcccggcct ggtcatgctg agttcattac gcgcacgctc ttcgagcgcc tcctggccgc
    65221 cattgagatc gtcaatttcg gcaaaaagtt gatcgtttcg cgctttaagt ttcgcgtttg
    65281 tagcttgctg tgccgccaca tcatcattga cgcgggtata gtcatgtata ccgttcttac
    65341 cgaaccacag cgaatactgt agccagacca gaatagccag caacagcagc gttagtttac
    65401 ccatcctgcc ccctgaaaaa cggcatcatc atcccatgca tccgaagacg actctacatc
    65461 ctctgttggg gataccgcga caacgcgggc aaatgtacca catttgtcca ttgttacgta
    65521 tacccagggc gtgcagaaca taatctcatt attagttacg gtttgaatta tgaacagagg
    65581 agacaagaaa gtacaaatta gcccagtagc cacataaaca gtgcgccaaa cataatgcct
    65641 actgtcacca gggtgaaaac aatactgtag cgtagctttc cgtccatcaa tgaatgcagc
    65701 gcaatcccca ccactaccgc gacaggcatc agtgccagaa agaaaggcca ggtgtagata
    65761 aagaagaaca gcgtgttaga gccataaatc aacatcggca tcgccagcgc aaataaccat
    65821 gagataaaac cgaccacggc accaggcagt gaccatgtgg tttcttcatc ctcagtaagg
    65881 ctgtcgttat ttgttagtgt aatgttatgg ctattacgca tatttgatcc tgttactttg
    65941 acgaaccggg catggaaacc cggtggtgtc tcaggatctg ataatatcgt tctgtctcaa
    66001 cagatctaat aattgctgta ccaaatttgt tactaattgt tcaccattga gatgaatttc
    66061 tgccgattca ggcgcttcgt aaacggaatc tattcccgta aagttgcgca gttcaccggc
    66121 acgcgctttc ttatataagc cttttggatc gcgggcttcg caaatcgcca gcggtgtatc
    66181 gacaaacact tcgataaagc gcccttctcc tacgcgttcg cgaaccatct ggcgttcggc
    66241 gcggtgtggc gagataaatg cggtcagcac caccagtccg gcttcaacca tcaaattcgc
    66301 cacttcaccg acgcgacgga tattctcttt acgatcggca tcgctaaaac cgagatcgct
    66361 gcataatccg tggcgaacat tgtcgccatc cagcagatac gtactgacgc cgagtttatg
    66421 taacgcctcc tccagcgccc cggcgaccgt tgatttaccg gacccggaga ggccggtaaa
    66481 ccacagcact acaccacgat gaccgtggtg tagctcgcgt tgttgcacag tgactggatg
    66541 gctatgccag acgacgtttt cgtcatgcag cgccattatt tatctcccag caaatcgcgc
    66601 gcgccccagt gcggaaagtg gcggcgaacc agagcattca attccagttc gaatacactg
    66661 aattgagatg gcgcagcagt tgcctggcta actggctcgt gcaccatacc ggcacctacg
    66721 gtcacattgc tcaggcgatc gattaaaatc agcccaccgg tcaccggatt ttgctgataa
    66781 cgatctaaca ccagtggctc gtcaaaggtg agatctacca ggccgatgcc gttcagcggc
    66841 aggttttcaa cttcgcgttg ggtaaggtta ttaatatcaa cctgataacg aataccatca
    66901 acacgagcac gcgtcttctt accggcaatt ttgatgtcat aactctggcc cggggaaagc
    66961 ggctgttccg ccatccatac cacatccacc gacgcgctct gcacagccgg taacgcttcg
    67021 tctgccgcca gcagcagatc gccacggctg atgtcgatct catccgtcag caccagggtg
    67081 atcgcttctc cggcaaaggc ttcttcgcga tcgccatcaa aagtcacgat ccgcgcgacg
    67141 tttgattcca caccagaggg cagcactttg acacgttgcc cgacttccac gcgaccggat
    67201 gccagcgttc cggcgtagcc acgaaaatcg agattcggac ggttaacgta ctgcaccggg
    67261 aagcgcattg gctgagcatc caccactcgc tggatctcca cggtttccag cacttctagc
    67321 agtgtcggac cgctgtacca cggcatactt tcactttgcg aagccacgtt gtcgccttcc
    67381 agtgcggaga gcggcacaaa gcggatatcc agattacccg gcagctgccc ggcaaaagtc
    67441 agataatctt cacgaatacg ggtgaacgtc tcttcactgt aatccaccag atccattttg
    67501 ttgatcgcca cgaccagatg tttgatcccc aacagtgtgg agataaaact gtgacgacgg
    67561 gtttgatcga gcacgccttt acgggcatcg atcagtaaga tcgccagttc acatgtcgat
    67621 gcgccagtcg ccatattgcg ggtgtactgc tcgtgccctg gggtgtcggc gataataaat
    67681 ttacgcttct cggtagagaa atagcggtag gccacatcaa tagtgatgcc ctgttcgcgc
    67741 tcagcttgca ggccgtccac cagcagtgcc agatccagct tttcgccctg ggtgccgtga
    67801 cgcttactgt cgttatgcag cgatgagagc tgatcttcgt agatttggcg ggtatcgtgt
    67861 agcaggcgac caatcagggt acttttgccg tcatcgacgc taccacaggt cagaaaacgc
    67921 agcaggcttt tatgttgttg cgcaatcatc caggcttcga cgccgccttc attggcgatt
    67981 tgttgtgcaa gtgcggtgtt catcttaaaa atacccctga cgttttttca gctccataga
    68041 ccccgcctgg tcgcggtcaa tcacgcggcc ctgacgttca ctggtggtgg aaaccagcat
    68101 ctcttcgatg atctccggca gtgtttgtgc atttgactcc accgcaccgg tcagcggcca
    68161 gcagcccagc gtacggaaac gcaccatccg ttttttaatc acttcgcccg gttgcaggtc
    68221 gatacggttg tcatcaatca tcatcaacat accgtcgcgt tccagaaccg gacgttccgc
    68281 agcgagatac agcggcacaa tgtcgatatt ttccagccag atgtattgcc agatatcctg
    68341 ctcggtccag ttagagagcg ggaagacgcg gatgctttcg cctttgttaa tttgcccgtt
    68401 gtagttgtgc cacagctccg ggcgctgatt tttcggatcc cagcgatgga agcggtcacg
    68461 gaaagagtag attcgctctt tagcgcggga tttctcttcg tcacgacgtg cgccaccgaa
    68521 ggcggcatca aaaccgtatt tgttcagcgc ctgtttcagg ccttcagttt tcataatatc
    68581 ggtatgtttc gcgctgccgt gtacgaatgg attaatcccc atcgccacgc cttccgggtt
    68641 tttatgcacc agcagctcgc agccgtaggc tttcgccgta cgatcgcgga actcatacat
    68701 ctcgcggaat ttccagccgg tatcgacatg cagcaacggg aaaggcagcg tacctggata
    68761 aaacgccttg cgcgccagat gcagcatgac gctggaatct ttaccgatag agtagagcat
    68821 caccggattt gagaattctg cagccacctc gcgaataatg tggatgcttt ccgcctccag
    68881 ttgccgcagg tgagtaagtc gtttttgatc cataaccgtt cctttgcaat accgctattt
    68941 tcttgccatc agatgtttcg actataggga gcgcaggaga acgaatgaaa ttaccaatta
    69001 gaatgagtag ttccttaacg gaataacgat ttggcaaagc taatgtcaaa aagtgcttaa
    69061 ggcaccagat ttcgggcgtt taggaagatt tgaaattgtt ttagcgcatc ggcagtttca
    69121 tactatggcg gtaaaaaaat ttgcatggta tttaaggact cactatgttt tccgcattgc
    69181 gccaccgtac cgctgccctg gcgctcggcg tatgctttat tctccccgta cacgcctcgt
    69241 cacctaaacc tggcgatttt gctaataccc aggcacgaca tattgctact ttctttccgg
    69301 gacgcatgac cggaactcct gcagaaatgt tatctgccga ttatattcgc caacagtttc
    69361 agcaaatggg ttatcgcagt gatattcgga catttaatag tcggtatatt tataccgccc
    69421 gcgataatcg caagagctgg cataacgtga cgggaagtac ggtgattgcc gctcatgaag
    69481 gcaaagctcc gcagcagatt atcattatgg cgcatctgga tacttacgcc ccgctgagcg
    69541 atgctgacgc cgatgccaat ctcggcgggc tgacgttaca aggaatggat gataacgccg
    69601 caggtttagg tgtcatgctg gaattggcag aacgcctgaa aaatacgcct accgagtatg
    69661 gtattcgatt tgtggcgacc agcggcgaag aggaagggaa attaggcgct gagaatttac
    69721 tcaagcggat gagtgacacc gaaaagaaaa atacgctgct ggtgattaat ctcgataact
    69781 taattgttgg cgataaattg tatttcaaca gtggtgtaaa aacccctgaa gcagtaagga
    69841 aattaacgcg cgacagggca ctggcaattg cgcgtagtca tggaattgcc gcaacgacca
    69901 atccgggttt gaataaaaat tatccgaagg gtactggctg ttgtaatgac gccgaagttt
    69961 tcgacaaagc cggtattgcg gtactttcgg tggaggcgac caactggaat cttggaaata
    70021 aggatggtta tcagcaacgc tcaaaaacac cggccttccc ggcgggaaat agctggcatg
    70081 atgtaaggct tgataatcaa cagcatattg ataaggcgct tcctggaaga atagaacgtc
    70141 gttgccgtga tgttatgcgg ataatactac cgctggtgaa gaaactggcg aaggcgtctt
    70201 gatgggtttg aaaatgggag ctgcgagttc taccgcaggg gcggggaatt ctaagtgata
    70261 tccatcatcg catccagtgc gcccggttta tccccgctgg cgcggggaac tcgccggaaa
    70321 atattcatga tgggggtggt tatggcggtt tatccccgct ggcgcgggga actcggggcc
    70381 gccgtgttca catttgccta atttcccggt ttatccccgc tggcgcgggg aactcaacat
    70441 gtctttcgtc aattttggcg ctataaacgg tttatccccg ctggcgcggg gaactctata
    70501 taaacgaggt gaatttatgg aaactgtacg gtttatcccc gctggcgcgg ggaactcgtt
    70561 agttttctga aaaaattgtt ttcttacgct ggtttatccc cgctggcgcg gggaactcaa
    70621 tattgtcgtg gacaaatgcc ggtgttattg cggtttatcc ccgctggcgc ggggaactct
    70681 tcgagacact tctctgcaaa attaatgaaa tcggtttatc cccgctggcg cggggaactc
    70741 caggtatcaa gaaataatcg aagccttcat gacggtttat ccccgctggc gcggggaact
    70801 caattgattg ctgggtgata ttggaaaatg ttgcggttta tccccgctgg cgcggggaac
    70861 tctaccgtac agactgccgg atattatttt tttgcggttt atccccgctg gcgcggggaa
    70921 ctccgacgtt cgacgaaatg cgcgatggcg gtcggcggtt tatccccgct ggcgcgggga
    70981 actcttctgc gtccccgatg tctggcccga ctggtccggt ttatccccgc tggcgcgggg
    71041 aactctatat gaccggaaca cttccgcctg acgtttgcgg tttatccccg ctggcgcggg
    71101 gaactctcta aaagtataca tttgttctta aagcattttt tcccataaaa acaacccacc
    71161 aaccttaatg taacatttcc ttattattaa agatcagcta attctttgtt tttaaacagg
    71221 taaaaaagag accaacctta aaccatccaa atctaccgga gtacgcctgt ttaccccaaa
    71281 tgtctggaac tcaaatcccg attccgtatt cgtagcccat gccatcacca cattgccttc
    71341 ttccgccagt ccagatattt gttcccagat catttcacgg attcttgcgg atacatcacc
    71401 tacatacacc cctgcacgta cctccaacaa ccagatggct aatctgcctc gtaagcgcgg
    71461 aggtacattt tcagtgacca cgaccaacat actcatttca gctactccga tggcctgcat
    71521 ctcccagtga aacaggaagc ggaatggcaa caggctgtgc atcttcaggt ggggccggcg
    71581 gttgtatttc tccagcagca agcacgtcct ctataagcgg aatcaatttg gctaatgttt
    71641 tactactgcg aaaaatatcc ctgcacgcca aacggacttc ccggtccggc tcaccaggat
    71701 tacgacgcgc tatctcaaaa gctttcggta caacagtgtc aaatttaatg atgtccgcga
    71761 tatcgtaaac aaaggaaaga ggctttcctg tatgcacaaa cccaatagct ggtgcataac
    71821 cagctgcaag tatcgccgct tcagttacgc catataaaca agaagttgca gcgctaatgc
    71881 attggttgac cgtatcgccc ttttcccagt ctttcggatc gtaacgacgt ccattccatt
    71941 tcaccccgta ttgcttcgcc agaagtacat aggttgctcg cacacgactt ccttctatac
    72001 ctctgagttg ctctacggag cgccgggcag gcgcaggttc tccaaaccga agttcaaaca
    72061 ttttacgtac gaccttcaga cgcaaatctt catccagagc aagttttgcc tgatagagca
    72121 gcttatctga acgcgcacca ccaggctgac cagaagcata aacacgaacg cccgcttccc
    72181 ccacccatac caataatgtt ccaacttgcg cagccaggcg tacagctgca tgcgaaaccc
    72241 gtgtaccagg ttccaacatg atgcaggcaa ccgagccaac aggaatatga gtgcggatcc
    72301 ctgtcttgtc gataagtaca aacgcgccat ctattacatc gatctgccca tattgcagaa
    72361 agatcatgga gacgcgatct ttaagtggaa tgggattaag gggaagccag gtcattttat
    72421 tacacctaaa tcacagtgga gccaaagata gcaagccaca tcccatcgat ttagctggcc
    72481 caataccttg ctgtacaaga tctattaacg ctggcgcgtc gttgatggtg atcacccctt
    72541 caaagcaaac cgtttgaatc tttccacttt taccatcacc agaaaaatac tgtggccgtt
    72601 ccgatatggg atgcacatct tcaacgcgcg ccgcattgcc caatttacgt tgcaaccacg
    72661 cgatttgttc tgcttctttt attaacggaa cccgacagcg tttaatattc cctttactgt
    72721 ccaggcgctt ttgattgtcg agaatagttt tgatcggatt tgcccgaagc cgaaaataga
    72781 gtggaacacc aacctgaagt tgaaattcaa cctgtttagt tttaatgact gtcgcaacgg
    72841 cagttgaaac aggcatttgc gctgactgca ataaaacatg acagccttct ggtgtgtttc
    72901 gcttctcaac atgaaaaaga aaatcacgag cagcatccgg tctgtttgga aataaatgcc
    72961 ataatccctg gtgaagttgg taaagatccc tgctccaggc cctggcaatg atgactttac
    73021 tgagatacat ccatacctcc tttaatcaca taccattctc gggaagcaaa ttgtcgaggt
    73081 aaggtgatca tcggttcgtc gcgcgccgta aattttaaat aatgccctgt aactgattcc
    73141 tcactataaa tatcgccgcc aacgggctca taatttaata gcgccttctg aggatccgat
    73201 gccttacatg tccccaaaaa aagcgggtgt gttagtgggc aacttctccg ccccaggtag
    73261 ggtgtatacc gaggctttaa tactgctttt tcaagttctg agataaccat cgttgcatgg
    73321 ggtgttaacc agagagcgac ggtaaaggag gcatcacata aatattcgcg ccatgtttga
    73381 atcgtttcat gacttttcaa accacggtaa tcttctcgcg ctccaaggac tgtatggtaa
    73441 tcacgcaacc ccgttacaga cacacgacga tcgtcaagaa tgagttcatc gcagcgcact
    73501 gcaaattgca cactctctga taacgcctgt aatgaagaag tatcatcacg ttggatccca
    73561 agacaagcac cgagtagccc taataacccg cttcgggtcg gaaatcttcc ggtaggtcgc
    73621 gttccttcaa aggtcggctg cccccaggct tgcattggcc cagcaagccg caagatcaaa
    73681 taagatctca tgttcacgcc tcgccattat tacgaaccca ggattttaac tgttctaaag
    73741 taggcatttg tttaacttga gcagtaattg ggtctacatc agataagctg aattgcgcag
    73801 cagctccgtt cagaccatat ccattggcaa cgcgatccca atattgatta aaagcctgta
    73861 tagacggttg caaaaagcca tctttcgctt taaccgcttt ttcaaaagca tttgccatag
    73921 aaagtggcat atcggagaaa ttaaccatta ccatatccgc agggttaaaa gcggcataag
    73981 tacgctgttt tgctccaggg acctctgttg ccagcatatg aacaacatgg gttgcaattt
    74041 ccagagcctg ctccctggag gcaccaccta aattttcctg aagttgagcg aggttaatgt
    74101 tggcataacg ataaaaaaca cccgatgaaa attcctgagt tcccagatgt gcagaacctt
    74161 gttcctgtaa atcatctaca gcggtgaacc agtcaatatc agaatcaacc tgatgagtag
    74221 tgatcgcatg cgcaatggac attgcaccat caacttttcc caactcactc atcatgccgc
    74281 tggttgccat tcttccacta agcgcaatat caacaccctg ctgtaaattc acacgtatgg
    74341 cggcaatatc ttccttaaga actttgagca gctttttatc atccagatta tcagcctctg
    74401 cttttgcaac ctgctcacag aaccaggcta tttctcccac aacccaggga gtaaccgcat
    74461 cggcagaaat cttttcggct tcatcaacta atttaccgga gagcagcgct aatgtcttat
    74521 cgatgatttt ttggtcaaaa cgttcaccaa gtttttgccg aagaacatca cgtaattgtg
    74581 caagatgaat tgttctgaga ctggattcac caatattttg tgcgtaataa tcacttttac
    74641 gcatcgcacg tttaaggctt tgacttgaaa ttcttactcg tcttttcccg ccgaaaatag
    74701 cgtctttctg catgttcata tcgtcgcggt tcagacatga agggctgtga gaaatcagaa
    74761 catgaatatt gataaagtta gacatagaaa ggtttcctta cgcatttttg tttgtggtca
    74821 atacaaaatc ttccagaagt tgctggcgtt cgcgctttcc ccaccaggtc aacatcctgg
    74881 ccattaatgg ccagtcaagt acgggttcgg cgtgagtaag taatcgacgt aactggacca
    74941 tatcggctgt tctgtcagac cgaattaatt gaaagatacg gcgctcgtta attcttccac
    75001 tattggctaa agctcttccc aacgagatac ctgttgtttg ctccggtttt ttgtcctgat
    75061 gtcggatgac attctttcct gcgctcaggc aaaacaccat gcgcaaaaga gcctgctggt
    75121 gacgtgggtt ttcccaacca aaaggttgca ccagcctata aaacgcaggg atatcgcgta
    75181 attcatcagg ttctgaaaca cgtctaattt gcgcacatgc tccattatcc agttgttgcc
    75241 aggctcgata taaagccatt gcatcaattt catcagccat ttgatggccc tccttgcggt
    75301 tttaactccc gtaaatgttt gtatagcgtg gcgcgggcaa gcgctaatgt gcttattaat
    75361 ttaggatgat gtgcataggg agcttcagat tgattaaata gcatttcaca caattgatga
    75421 agtttgtctc gtaaatcagc tattacctca tcagcttggg aaaaattaat attcgccagt
    75481 acatcgggaa ttaataattc actctgtcga tagaaatgcc tttctgcagt ctcatgaaca
    75541 gagactccgg cccctttgaa atctttattt ttaaaccctt ctgcaaaggt atataacgcc
    75601 ttgcgtaagg ctgttttata tcccaaacca acagtcacta tttcgtttat cacattgccg
    75661 tattgttgcc acccctgatt aaacatcaac acatcatgac gccgttcaag aatagatgct
    75721 tgattattac gatatccccc cataatcaat tcaagaggac tttgcggcgc aatatttctg
    75781 aattgattca caaccgccgc cacgcgattt ccattttcat tttgaataat cttatctacc
    75841 acaactcggc tgatttgtgt ccatgatggt gcggaggtgg tgaaagcaag aaatttttcc
    75901 tcaacctccc ctttcttgac tgttaccaga caaggggaat gcggatgggg ccatagccca
    75961 ttaactgtaa aggtaaattt ttccttaaga aaaccggtat aacgcaaatt gctttcctgt
    76021 ccacagcaag aacatttacc aatcccaatg ggatcgcata attcaatatg cgctggttgc
    76081 cagaataagc cacggacaaa cccaattgac gaagctggca cagattcatt gggtttgaca
    76141 ggcttaaccc aggtaggttg gttttccgta tgtaattcat tgggaaattg tttttgaaga
    76201 cgaggtattg tgaggacatt gagtaatacc gtcgagcgaa gatcgatccc acatacgaag
    76261 gtggttatag gtgttcctcc acgtaaaccg cttttaaagc caccaccaaa accaggtgcc
    76321 tgattcgcct ggttgaataa cgcaatcgca gtgcatccac cacataatgc ttcaccctgc
    76381 cccggttgat tgacaaatgc acaattcgtc gcgccgctta ccccagccaa cagtttttcc
    76441 attggagtca catcatttgc tttgacacct ttggtctgca taaagggatg ttctgcgtga
    76501 ttaaggtaga acatatctat ccacggcgcg atgagttgtt gaaactcatc ttcagtgagc
    76561 ggattcatta tgcgatgtcg aaattcaacg tcatcttttg ccggggcgat aatttgccca
    76621 atgcaaacca gcagtgctaa agcggccagt tccatatcgt cacggggcaa acttaatcgc
    76681 cactgatctc tactgcagta tagcgattgc agatttatga tttggacttc ccccccgttt
    76741 cgcgggcgta cagggatcca gttatcaata agcaaattca tttgttctcc ttcatatgct
    76801 ccgacatttc tcctgcattt ctatacgtcg gcacacttcc gttatcggta aaaacaaaga
    76861 aaaaatacgg cgtaattaat tcaataatca cattcactgc aaaaatatat tcattggttt
    76921 aatacaatta acctatgcat atattaagat gtgttgaatt gtttaaagac aataatgcat
    76981 gcatttcaaa tctgcaagtt attcgtttta ttatcaaaga aatttttagt tataataatt
    77041 accataaatt ttattacata aaatattcat actgtgaata taaaatctca taccgggaaa
    77101 ttaaaagaag atgtacattg tgcaccttcc ctacttaagt agggataaac cgttattggt
    77161 cttgttatcg tcattgatac caatcattcc cgaagttatt tgggatttgc agggatgact
    77221 ctggtcatcc cttcatcccg agtgtaggta ataacaatat tattaccctg ccagatccat
    77281 ccatcctgat tctgtttccc ttccagccaa agtaccccat cttcatctac tacttcagaa
    77341 aaattacgtt tccaggtgaa gggtacattg acgcgattaa gtgctaacgc ctcatactgc
    77401 tgttcatgac ttaggtcctc gtagacctgg ccatcgagca gttgtttacc tgaagacgtt
    77461 tgtaaataag gcaataatgg caggctcatt tccccatccc tcgttaccgc aagaattgtt
    77521 tcatcgttat cctgcaagct atattcttca gcccactgca gaaccttgcg agccttgaac
    77581 ctcttttcac actcagcact ttcatactta tccatgcctt tgatgaccca ttctggctca
    77641 tccatttcag catcatcgta aatgctatcc agccattgcc ggtaggcatc agggaaaaat
    77701 aaggatgctc cattaagttc ctcaatatgt tgctgcgtcc gccacatgac tctaacgttg
    77761 ctataaatat gctcatgtcg tccgtaacct tcgccatcag gcagcaaaac gctggcaaga
    77821 ggaacctcaa aaccagcggg acgatatttg cgatgatggc gatgtaaacg gcccaatcgt
    77881 tggaaaagta aatctgcggg gcaatgctga gtaattaacc aatcaaaatc aacgtcgagt
    77941 gattgttcca cgacctgggt ggcgacaagt atccgtccaa catttcgctt cccatttttg
    78001 ccgaaattgc taataactcg attctctttt tcacgacgat cgttcagcgt aaagcgcgca
    78061 tgaaacaaat ctatatctac ttgcgtgtta tttagttcct ttaaccgttg gtggcatagt
    78121 tgtgcaacat caaccaaatt gcagataaga cagacttgtg cacccgcatt tgccgctacg
    78181 atcattcgct ctaacatcct aaggtcaggt aacatgtcag ctaaataaat aggttctggc
    78241 cgaatcgaaa agcggggcgg gagttgttct gaatgagcta acagatcaaa acgttgtgca
    78301 ccattcacac ctcgccagtt aatgagtgga tatgcggagt tattttcctc tggatctgta
    78361 tgcagaccat aagtatccag aagtttctgt ttttgtttca ttggtagagt tgcggaaaga
    78421 agaataacac tcccccccac atcagcctga gccttgagca cagcctccag caagccgttc
    78481 atatacgtgt cgtaagcatg aacttcatca acaattaaaa cacttcgacc aattcccaaa
    78541 ccacggataa agcggtgttt aactggcaat accgatatca acacctgatc aatcgtgcaa
    78601 acgccgattt gcccaagaaa cactttctta ttgctttgtg acaaccactg acaacactga
    78661 acccatgctt cttcttgccc ctgctcagta aatgcgcgtg attttattga ttgaaaaagg
    78721 tggttaaaac gtgaattacc atgagcaaga ataagatttg gggaggtaaa taaacggctc
    78781 gcgttcgctt ccattctgct gagcattgca tttgcagtag cttgtgtagg gagggcaaaa
    78841 ataacactat ccgcaagttg ttggtcaata agtttccagg cataggccag cgctgtttcg
    78901 gttttacctg atcccgtagg tgcctcaatc accgtcagcc cgggagctgc aggaagagca
    78961 tcaactaaca cttgtaattg tctgggttga tagccattgt ccagtagagc atgaacacct
    79021 tcataacatc gcttatttga tacaaggccg ctcaactcca atacccggct cgcatcctgc
    79081 tgtcggtcct ggaaatacgt tcttagagca tttatgttgg aaggtgcatc ctctttaaac
    79141 agaaaggtat tcgttgtagt ccaggagcct aaccagtcag caagcgagca aaaacctgct
    79201 aacagtgatg aacaatcagg tggtatatcg tttatagata acccggctgg cgttaaaaat
    79261 aatgcttcga gtacagatat ccactcctca cgagcctgtt tatcttgcgc agcataagat
    79321 gccagagaag ctggcatttc ccaacgcgac ttatcttgat cctgggaatg taatataaaa
    79381 ccatgatgtc ctgtaacggc ctctacccat ggaaaccagg actcataagg atgaggagcg
    79441 gcatcaaaaa aactgaaaaa atccccggga gattgctctg aaagtgaatc ctggttaaac
    79501 caatacagac cggctgcacc atgattaaat ttacggcaca tttgtgttga tggaccatta
    79561 agtgatggcg ttgcaggatt taatttcagc caactttctg ctgatttata ttggaatcgt
    79621 atatcaaact ttccgatatc atgaagggca atgaaaaata acagccaggc tttcaccatc
    79681 tgttttgata gcatttcatt ttggcaaaaa gcattttgta gtacgactga ttgttcccac
    79741 cagcaatctg caacagctgc aacatccagg caatgataaa tcaacagatg aatatcattt
    79801 cctttcgtca ggctttttga ggatttcccc cagtaatgac atatatattt aaaaggttcc
    79861 attaatagcc tccctgtttt tttagtatta tcgatgatat cagtggacta tttttcgatg
    79921 ctgctcataa atatcgaatt acagtgatat acacatgtct tgcctccctg caaagaagag
    79981 actaacatcc gaattgctta ggttcgaacg ctggcctcag gttgatagaa atatcgcctg
    80041 gggcttttgt ccatctggta cctcgcgaat gcttaatgcc agacagcctc aagcacccaa
    80101 cgccattcta tacctgttaa ttcttccaac gacgttcacg tttaaaatca ggaatgctgc
    80161 tcgcaaaata aaaacgcccc catcatttct gacagaggcg tttaatttat ccggcaatat
    80221 ttacccttcg tgtaatccac attccctttt taagccaaag aaacgcgttt cttcttccgc
    80281 catgccgggt tcccatttac gggttgtatg ggtatcgccc accgataaat atccttcgtc
    80341 ccataatggg tgatatttca ggccatgttt ttgcaggtac tgatatatcg ttcggttatt
    80401 ccagtcgata atcggcagca ctttaaatac gccacgctga attgccagca ccggtaaatt
    80461 ggcgcggctg ccggattgtt cacggcgcag gccagcaaac cacgtttgcg cattcagttc
    80521 tttcagcgcc cggttcatcg gttcgacttt gttgatgtca ttgtactttt caatgccttc
    80581 aacgccctgc tcccacagtt tgccgtagcg tgcttcctgc caggcggcgc tttcagtagc
    80641 acggtacact ttcaggttga gcttgagttt gtccgttaac tcgtcaataa agcggtaggt
    80701 ttccgggaac agatagccgg tatcggtgag gatcactgga atatccgggt gaatctgatt
    80761 caccagatgc aggctcaccg ccgcctgaat gccaaagctg gaagaaagta catattcacc
    80821 aggcagatta tccagcgccc aggcaacgcg gccttcagcg tccagttttt ccagttcggc
    80881 gttagtttcc gccagcgcca gaatgcgatc taccttcggc agttcgttca gggcgtttag
    80941 atcgagtttg gacatagatt cctcactgtt tgccttgcct gatgcgacgc tcacgcgtct
    81001 tattaggcct acaagaccgg gctgatggtt aatcccataa atcgcgcgcc ggatcgagca
    81061 ccgggcgaat gatgcccgca cgcaccgtaa agtcgccgaa gccttcaccc gcttcgcgct
    81121 ctttcgccca gcgccctatc agttcatcaa gcgacgccag gatttccggc tcggtgatgt
    81181 tttctttata catccgtggg atacgtgtcc caatgcggtt gccgccaaga tgcaggttgt
    81241 agcgacccgg cgctttcccc accaggccca cttccgccag catcgcgcga ccacaaccgt
    81301 tcgggcagcc tgttacacgc atcacgatat gctcatcgct gacaccatgt ttcgccatta
    81361 aattatcgat gttgtcgata aaagacggca ggaaacgctc cgcttccgcc atcgccagcg
    81421 ggcaagtcgg gaatgacacg caggccattg agttttcacg ctgcggcgtg acggcattca
    81481 ttaacccgct ttctttggcg atcttctcga tcttcgcttt ctcgctttcc ggcacgccgg
    81541 cgatgatcag attctggttc gccgtaatgc ggaaatcacc tttgtggatc ttcgcgatct
    81601 ccagcaggcc agttttcagc ggacgccccg gataatcaag gatgcgacca ttttcgataa
    81661 atagcgtcag gtgccagtta tcatcaatgc ccttaaccca accaatacga tcgccgcgtc
    81721 cggtgaactc atacggacgg atcggttcaa atttgatccc cgcgcgacgc tccacttccg
    81781 ctttaaacgt ctcaaccccc acgcgctcca gcgtgtattt ggttttggca tttttacgat
    81841 cggttcggtt accccagtca cgctgagttg tcacgacggc ttccgccacc gccagcgtat
    81901 gctccagcgg cagatagcca aactcactcg ccgtgcgggc gtaggttttc ttgttgccgt
    81961 gttcgataga aagcccaccc cccaccagca ggttaaagcc caccagcttg ccgttttcgg
    82021 cgattgccac gaagttcatg tcgttggcat gcagatcgat atcgttctgc ggcgggatca
    82081 ctaccgtggt tttgaattta cgcggcaaat aagtctgacc gaggatcggt tcttcatcgg
    82141 tggtggcgac tttttcctga tcgagccaga tctccgcata cgcgcgggta cgcggcagca
    82201 gatgttcaga tattttctta gcccattcat aggcttccgc gtgcagctgc gactcgtaag
    82261 ggttcgaggt gcagagtacg ttacggttca tgtcgttagc agtcgccagc gcatcaagac
    82321 cgaccgagtg cagcatctgg tgcaccggtt tgacgttctt tttcagaatg ccgtggaact
    82381 gaaacgtctg gcggttggtc aggcgaatgc tgccatagat ggtgttttca ccggcaaatt
    82441 tatcgatcgc ctgccactgt ttggtggtaa tcaccccacc cggcagacga cagcgcaaca
    82501 gcatcgcgtg gcgcggctcc agcttctgtt cagcacgttc ggcgcggatg tcgcggtcat
    82561 cctgctgata catgccgtgg aagcggatca gcaggaagtt gtcgccctta aagccgccgg
    82621 tcagaccgtc gtttaaatct tccgcaatgg tgccgcgcag gtagttgctt tcaagcttca
    82681 tgcgctcggc gtctgtcagt tttccttcga ccactaaagg ccctggatgt ttttcgctca
    82741 ttagtagaca tctcgctgat aacggcgctc tacgcgcagc tcacttaaaa attcatccgc
    82801 cgcttcggtg tccatgccac caaattcggc aatcacttcc agaagtgcct gttcaacgtc
    82861 tttcgccatg cgattagcgt cgccgcagac ataaatgtgg gcaccgtcat tgatccagcg
    82921 ccacagctct gcgccctgtt cgcgcagttt gtcttgtaca taaacttttt ctttttggtc
    82981 gcgcgaccag gcaagatcga tacgcgtcag cacgccctct ttgacgtagc gctgccattc
    83041 cacctggtag aggaaatctt ccgtaaagtg cgggttgcca aagaacaacc agtttttccc
    83101 cggcgcttcg tcggcggcgc gttgctgcat aaaggcgcgg aacggcgcga tgccggtgcc
    83161 tgggccaatc ataatgaccg gcgtttccgg gttcgccggc agacggaagt tgtcgttgtg
    83221 ctcgataaag acgcgaactt cgccctcctc ttcgacacgg tcagccagga agctggatgc
    83281 accgcccgcg cgagcacggc cttcgatgtc ataacgcacc acacccacgg tcacgtggac
    83341 ttcgctttcc acttccgcct gcgaagaggc gatagagtaa agacgcggcg tcagtggacg
    83401 taacaggcca accagcgctt ctgcatccag ctgtgctggc gcgaaacgca ccatatcaac
    83461 aatcggcgtg gtggccgcat agtgctgcaa cttcgcttta tcgcccacta acggcagcaa
    83521 ggattcgctg cgcgtcaagg tggcgtaatt ctcaacgatg ttggccgtgt tgacggtcag
    83581 ttcaaaatgc cactgtagcg cctcattcag cggcagggtt ttgccctcaa cggtgacagg
    83641 ttcatcacct ttcagccaca gcagttcgac aagttctttc accagtgccg gatcgttctg
    83701 ataccagacg cccagcgcgt cacccggctg gtaacgcagg cccgagtcac ctaagtcaat
    83761 ttcgatatgg cgaacgtctt tttcagagtt acgcccggta attttctggt taacagagag
    83821 gctcgccacc agcggcgcgt ctttgctgta cgggctggtg tggatttcat ttaccgcgcc
    83881 agtagcgacg gattgcgaag gtgccgcgac aggcgcacgc gatttaagcg catcaaccac
    83941 gcgggcgcgc cactcgctgg cagcggcctg atattcaacg tcggcatcga cacggtcgag
    84001 caggcgttca ccgccctgtt ccgccagctt gctgtcaaaa tctttcccgg actggcagaa
    84061 aaattcataa gagctatcgc cgaggctaaa cacggcaaat gcggtgtttt ccagcttcgg
    84121 cgcttttttg gagaacagga acttatgcag cgcgacggct tcttccggcg gttccccttc
    84181 cccttgcgtt gacgtcacca cgatgagcag tttttcgctg gcgatttgtt tgaatttata
    84241 gtcgcccgcg ttcaccagct taacgttcag ttttgccgcc aataaatcat cgcgtaatgc
    84301 ttcagcaacc cggcgcgcat tgccggtttg cgaggcggag ataatagtta tacccggcat
    84361 ttctgcggcg ggcgctggcg tcgctgcaag cgcagcaggc tgctggttga gcacgcccca
    84421 gaaatagcca gaaacccagg caagctgggt aggagttaaa tcggtcgtgg ccgcctgaag
    84481 gcgtgccagt tgctccgggt tcaacggaag caacgcggaa ggtgggacct gtgtcgtcat
    84541 gcgtcgttat gttccagtaa gcaaagctgt ttctgcgccc tgtcagcgcc cataaaacag
    84601 aagagaaggt aaggttaacg gggtgaacgg tgtggattaa agacgggata gcgataacta
    84661 ataaccaaat cgactaacct gttttagcaa tagtctttaa caacaaaata gattaaccaa
    84721 cccaatgaaa aacaaatgaa tattgcccat caataagata aatcagcgat tttgcgcaac
    84781 aaagtcgttt tagataatgc gaaaaaacag cctttccggt actctacggc ggttttatcg
    84841 tcatgtagag aaattatgat gtccaccacg ttatttaaag atttcacctt cgaagccgct
    84901 caccgcttgc cgcacgtccc acaagggcat aaatgtggtc gcctgcacgg gcattccttt
    84961 atggtgcgac tggaaattac cggggaagtc gatccgcata cgggctggat tatcgatttc
    85021 gctgaactga aagcggcgtt taagccaacc tacgagcgcc tcgatcacca ttatctcaat
    85081 gatattccag gtctggaaaa cccaaccagc gaggttttag caaaatggat ttgggatcag
    85141 gttaaaccgg ttgttccgct gttaagtgcg gttatggtga aagaaacctg caccgcaggt
    85201 tgcatctatc gcggcgaatg ataagagtgt gtcggcggtc aatttccctt aagtaacgct
    85261 atgttagggt gttgtgttct ggatatttgg ggcatgacat ggaagacgac tgcgacatta
    85321 ttattattgg tgccggtatt gcaggcaccg cttgcgcgtt acgctgcgcg cgagcgggtt
    85381 tatccgtttt gttactggaa cgcgctgaaa tccccggcag caaaaatctt tccggcgggc
    85441 gtttatatac ccaggcgctc gcggaactcc tcccacaatt tcatctgacc gcgcctcttg
    85501 aacgacgcat cactcacgaa agcctttccc tgttaacgcc ggatggcgca acgacgtttt
    85561 ccagcttaca gcccggcggt gaatcctgga gtgtattacg tgcacggttc gatccgtggc
    85621 tggttgccga agccgaaaaa gaaggtgtcg aatgcatccc cggtgcgacg gtggatgcgt
    85681 tgtatgaaga aaacggcagg gtgtgtggtg tcatttgtgg tgacgatatt ctccgcgcct
    85741 gttatgtggt gctggcagaa ggtgccaaca gcgtcctggc tgaacgtcac gggttagtga
    85801 ctcgtcctgc tggcgaagcg atggcgttgg ggatcaaaga agtgctgtcg ctggaaacat
    85861 ccgctattga agaacgtttt catctggaga ataacgaagg cgcagcgttg ctgttcagcg
    85921 gcgggatctg tgatgactta cccggcggcg catttcttta tactaatcaa caaacgctct
    85981 cgttagggat tgtttgcccg ctctcttccc ttacgcaaag tcgtgttccg gcaagcgagc
    86041 tgctggctcg ctttaaaacg catccggcag tgcgcccgct tatcaaaaac acggaatcac
    86101 tggagtatgg tgcgcatctg gtgccagaag gtggcttgca cagtatgccg gtgcaatacg
    86161 ccggtaacgg ctggctgctg ctgggcgatg cgttgcgcag ttgcgtcaat accggaattt
    86221 ccgtgcgcgg catggatatg gcgctaactg gcgcgcaggc ggcggcacaa acgctgataa
    86281 gcgcctgcca gcaccgcgag ccgcaaaatc tgtttgcgct ttatcatcac aacgtagagc
    86341 gcagcctgct gtgggatgtt ctacaacgtt atcagcatgt tccggcgctt ttgcaacgcc
    86401 ctggctggta tcgggcgtgg cctgcgttaa tgcaggatat ttcccgcgat ttatgggatc
    86461 agggtgataa acctgttcca ccgctgcgcc agttattctg gcgtcattta cgtcgtcacg
    86521 gcctgtggca tctggcgggc gatgttatca ggagtctgcg atgtctgtag cccgtaatct
    86581 ctggcgcgtt gccgatgcgc cgcacattgt tccggctgac tccgttgagc gtcagacggt
    86641 acaatggttg attaacgctt gtccggctgg tcttttttcg ctcacaccag aaggtgactt
    86701 acgtattgac tatcgcagtt gcctggagtg tggcacctgc cgtttgctgt gcgacgaaaa
    86761 aacactacaa cagtggcgct atccaccttc cggattcggc atcacctacc gttttggata
    86821 aataataagg ataatttatg cccctcttac acctgctccg ccagaatccg gtgattgctg
    86881 ccgttaaaga taatgccagc ctgcaactgg caatcgactc tgaatgccag tttatttccg
    86941 tgttgtacgg caatatctgc accatcagtc atatcgtcaa aaagattaaa agtgccggga
    87001 aatatgcctt tattcatgtc gatttgctgg aaggcgcatc gaacaaagaa gtggtgattc
    87061 agtttctgaa actggtgacc gaggcggacg gcattatcag cacgaaagca tcgatgctga
    87121 aagcagcaag agcggaaggt tttttctgta ttcatcgcct gtttattgtt gattcgattt
    87181 cgtttcacaa cattgataag caagttgcgc aatcgaatcc ggattgtatt gagatcctgc
    87241 ctggctgtat gcccaaagtg ctgggctggg tgacggagaa aatccgccaa ccgctgattg
    87301 ctggcgggct ggtgtgcgat gaagaagatg cgcgtaatgc gattaacgca ggtgtcgtgg
    87361 cgctttccac cacgaatacc ggggtctgga cgctagcgaa aaaattgctt tgacgggata
    87421 atcgtaacga attgaatttg tgtgatttgt aggctgtacg ccacatcgga cattcagcgc
    87481 ctgatgcgac gcttgacgcg tcttatcagg cctacaagtc cccaggccag aaccgtaggc
    87541 aggatcatcc agcaacacgt tattggcaat ctgcgtgaat gtttgtcacc attgcctcca
    87601 gcaccacttt ccagtcatca accacgccaa catctgcctg tgaaaatacc gctgcgctgg
    87661 cgtcatgatt aatcgccacc acaaacttgc tattgcatac gcccgccatt aacgctgctg
    87721 cgccagaagc gccaacaaca atacacacct caggtgccag cagatgtccg gaaataccaa
    87781 tcactttttc agcatcaacg ccaccgttca tcactcgcgc ccgactgtag cccacttcgg
    87841 ctcccagctt ttctgccagc atagcgattt cctggttatc tgcctctccg ccctgcccca
    87901 ccaccagcac ccgtctggct tcagctaatg ggtcgcgggt aacatttttc aggttttcta
    87961 ggctaaccag ccagtcggga agcgcgccgg ggacaatgtt cagttgctgc atcccagagg
    88021 gcaacgtggc gtttttatct gctcccgcct gacgcgccag cgaaaggcat agcgggcgtt
    88081 tgtctgtttg cagcgtcgcc gtcaacgcat ttccccagtg ggatttgcgc acgcttacgg
    88141 ttggaatatc taacgaagtc acctggcaga tgcttgcacc atgtaaacgc caggccagcc
    88201 gggtcgacag ttcatcgcca aacgttcccg gcggaaagag aacaacgtcc gcaggcgttc
    88261 gctgccactg ttccaccaac gcatccagca cctgttccgc cactacgggc tgaggttcaa
    88321 tctgccagtg cgccagggta caaccgctga aatcctgcgc cgccagccag ctcgctattg
    88381 cggcattctc ctgatttatt gtcacaattg cgatattcat ggctgcatcc tttggcgtaa
    88441 atagttctgc catagctttt gcgctttttc tgctaccgtt tgcccatcaa tcagcgtcgc
    88501 tccgcgtcgt tgctctgctc ttgccagatg cagacactgc atcgctggca attcgacagc
    88561 aacagtttta cggataattg ctgctttccc cgcagccatt cgctggcgca ttcccggtac
    88621 tggcaaggcc acttcaccac actggcgcac ggcaatcacc gcaggcaagc gaacccggca
    88681 acagcgcagc ccgttttcag tacgctgttc aagggtgata aacggcgcgt cgagagtaaa
    88741 acgctccacc tgggtgaagc agggccagcc cagcatttcc gccagcaaaa atggcgtttg
    88801 cccattctgc ccttcgctgc tttggcagcc ggtaatgatc agatccagcg gattctgacg
    88861 ctgccattcg gcaatatggc gagcgacaaa ttccggcgca aagcgcagat ctgccaccgt
    88921 ctccagcaat acagcgtcct caaacccaag agccatgaga tagcgcagcc agtgcaacgc
    88981 ccgttcatcc cccatgctca acgcggttaa agacatcggc gtaccgtttt ttctctgcgc
    89041 caacagcagc gcggcggcag cctgttcatc agcaccgagt aaacttcgca gtagcgaaac
    89101 atctggtcca atattaccct gagccgccgc ctgccactct ttttccgcca gcattccggc
    89161 atccggttcg gctttaaacg ctaacagaat gttcattcgc acctcctaca tttcccgccg
    89221 ccaccagcgg gagtgctttg gtttctggtg cccatagcca ggtcacaaca aaaccaacca
    89281 acaacactgc cgccaggagc aataaggtgg cttgcattcc ccactgcgcc agcacccacg
    89341 gcagcaggcc agtacttacc gccgccccca accgactcat ggcggtggca aaaccgacgc
    89401 ccagcgagcg aatgtcagta ggaaaacttt ccgcaggcaa aatgcccacc agattactga
    89461 ctgccgaaat ggtggtgctg aagagaacaa aaagcagcag cgttaatgaa ctgccggaag
    89521 gcaaacaggc catcactacc agcgttgccg ccagcagcaa aaaacttccc agcaaaaact
    89581 tgcgatgtgc cagcaggtgc gtcagaacta atcccagcag cgcgcccaca attaacaacg
    89641 cattaagcat caggctggcg gtcagcgcat cctccagacc aatagtctgg gcgatggtcg
    89701 gcagccaggt ataaatcaca aaccatggga ttacgaggca gacaaagaag acgctgttaa
    89761 acgccgtgcg tcgccagtag cgcgaagaaa acaaggtttt gatgtgttta tgggtcgccg
    89821 ctgccacttc atcgcccagt aaaacatgtg gccccaaata gcgatgcaca atagcgtgag
    89881 cttcagcaaa acgtccctgg cgcagtagcc agcgtggcga ttccggcgtg ccccaacgta
    89941 gcagcgtaat cagcaaggct ggtaacgccg ctgatgccag cagccagcgc caggcctccg
    90001 ggttttcgga aataaagtga tgtccggcaa tacttgccaa cacatagcct acggtccaca
    90061 ccacgctgaa tgcgcccagt aaaataccgc gatggcggcg cggggaaaat tcagccagca
    90121 aggtgtgacc gactgagtaa tcgcctccca gaccaatgcc gatcaaaatg cgcagcccaa
    90181 taagatgctc tggcgtggtg gcaaaaaatt gcaagaacga agcgagcgta atcagcaaaa
    90241 agctgaaggt gaagattttt tgccgaccaa tatggtcgga gatccatcca agaaccaggc
    90301 tgccaagaaa caaaccaagg agtgctgagc cgccaatcat tcccgccata aacggcgtca
    90361 gttgcatggc tggagtaagc tgaataatgg cgtaaccaat gacgccgagg acataaccgt
    90421 cggtcaggtg cgcaccgaaa gtgagcgcag caatgcggca gtgaaaacgg ttaagtggta
    90481 aatcatccat tcgcaccggt gaagtgttca tctttacccc ttcattgtcc ggtaataaga
    90541 acggcttctc gcctgagaag ccgaaaaggc aacgccccgt catcgcggaa cgctgcctca
    90601 cacattattt ttcaatcgga tagatagtac ccgtattcat aatgccgtta ggatcgaact
    90661 gttttttcag cccttccagc aacgtccacg cgctgccgtg ttccagtttg ctccagtgaa
    90721 cgcgatgttt accaataccg tggtggtgca ccatcgaacc gccgagacga atggtttctt
    90781 cgcagatgat tttgttgagc ggattgtggt acttgtcgat ttcctcttcc ggcttacagt
    90841 caacgacgtt gtagtcgtag acgaagtaca tgttggtacc gttctgatag ctatgagagg
    90901 agtgaccgcc cagcatggtg atgtcgtcgg cgtgcgggaa ctcggtacga atacggttaa
    90961 taacgctttc gtagatttcg tggatgcagc tccagcagcc ggacacttcg gtggtaaagc
    91021 ccatgttgcc ggttttgagg atctgcacac gttcagcggc cactttatcc ggcccccagt
    91081 tcaggtgatt aaaccaggtt tcgatcagct tgctgtccac gcgctggcat tgcgggtaac
    91141 gtgccacgat ttcagcaatc ccttcgcccg tcgccttcgc aatgcgaggg ttaccttcag
    91201 ccataaagat cagcacgcat ttaccatcgg caaaatgggt gaagtgttgg gtgccatctt
    91261 caacgtcata taaacgagcg atcgacggac gatacccttc caccatgatt tcacgcagga
    91321 tgttgaagcc ggttttcata tcttccagga tatagccgta gaagaggttg ttttccgggg
    91381 tgaatttaaa gattttcact gttacttcag tgatatagca cagtgcacct tcgttgccga
    91441 tgatgatgtg acgaatgtcc gggccagccg cgcggcgtgg cacgttttta atacgtgtga
    91501 cggtaccatc tgccagtacc gcttccagac caacgaccat atcttcgatt gcgccgtaga
    91561 gtgtggagaa ctgcccgata ctgcgggttg ctaccaggcc gcccatctgc gccagcggtt
    91621 ttgattgcgg tgaatgcccc gtggtgtaac ctttttcacg caacgcgttt tccagcacct
    91681 ccagcggaac gccacattgc gccgtggcct gcatattctc aatatcaata ttaatgattt
    91741 gattcatggc agagccgtcg agcaccaccg agttttccac aacggtttcc agcccgcctt
    91801 cagtggcgga agcaccggta cgcggcacac cgttaatttt gtgcgcattc ataaaattca
    91861 gcacacggga cacttgttct gtggaaccga gttttacgac cgctgccgga atcggcaaag
    91921 tataaatgcc atgaatatcc ggaaatttgc gaaaacggtc aatactgttt ttctttaata
    91981 ctgtttcatc ggtaattacg cgatctgcac caacaatttc ctttagctgg tcgacaatcg
    92041 ctgcgcgaga taaagacata gtaattcctt cctgataata aaaatggaat aatcattaat
    92101 aagagaaaac agaaaccacc gttatggatt agcgcactaa ataaccgcca tcgaccacta
    92161 ataaatgccc gttaacataa tttgaagccg gacttgcgag gaagacggct gcgcccatta
    92221 aatcctgtgt atcgccccaa cggtttgccg gaatatgatc aagaacgcgc tgattagttt
    92281 caggattact gcgtgtcgcc agcgtaatat ctgttgcata ataacctgga gcaataccat
    92341 ttacctgaat attatattga cctagttcat cacaataagc tttggtgaat ccagcaagag
    92401 catgtttagt tgcagaatat gcaggtgacc attgtccacc taagtaagag aacaatgaac
    92461 agatattaat aattttaccg cttttctgcg ggatcataat ttttgccgct tcgtagctta
    92521 actcgaatgc ggcggtcagg ttcacatcaa tcatcgggtc ccagtcggca cgaccgaagt
    92581 ccagcacctt attcagctta caaataccgg cattgttaac cagaatatct acggtaccga
    92641 agcgctcaca gcaggcagcg ataatcttct gcggcgcgcc ttctgcggtg atatccacct
    92701 gcataaaatc aacttcgaca ccctgttttt caatcatttc ctttgtttcg ccgttatctt
    92761 tgacgaagct agggataaag acatttgcgc cagctttggc caacgccatg gcaaatgcct
    92821 ggcctaaacc gctattcccg ccggtaacaa ttgctgtttt acctttcagg gagaaaaaat
    92881 ccattgagaa cgcattgaga gattcgattg acatagttag ctccaatttc cgtaaggcaa
    92941 aaaaaaagaa aggtaacttc ccccgcgaga gggaagttac ctttctcatt atctctggta
    93001 actggagata atttttagca taagggcata agcgctaatg tgatcgtaat cacagtgtga
    93061 tattcgtatt atcaaataat tttaaaaagc agaagcgtga ctactctcac acaacaccac
    93121 tgctttccat gttatttctt attgcaatta ctagagacct gagaaaagta atccacctga
    93181 aagggcggct tacttttctc ttttttttgt ctattacaaa tgggaatacg atatgcaaca
    93241 caactcatat cgccgttgga taaccctcgc gataattagt tttagcggcg gcgttagttt
    93301 cgacctggct tatttacgtt atatttatca aattcccatg gcgaaattta tgggattcag
    93361 caataccgag ataggtttaa taatgagtac ctttggtatt gcagctatta ttctttatgc
    93421 gcccagtggc gttattgccg ataaattctc acatcgcaaa atgattactt ccgcgatgat
    93481 cattaccgga ttactgggtc tgttaatggc aacttatcca ccgctgtggg taatgctctg
    93541 tattcaggtc gcctttgcga taacgacgat tttaatgctg tggtcggtgt cgattaaagc
    93601 cgcatcgttg ctgggcgatc atagcgagca agggaaaatt atgggctgga tggaagggct
    93661 gcgcggcgtc ggtgtaatgt cgctggcggt gtttaccatg tgggtctttt ctcgctttgc
    93721 accggatgac agcgccagcc tgaaaacggt cattatcatc tatagtgtgg tttacatctt
    93781 gttggggatt ctgtgctggt tttttgttag cgataacaac aacctgcgca gtgccaataa
    93841 cgaagaaaaa caatcattcc agcttagcga catcctggct gttttgcgca tcagcaccac
    93901 ctggtattgc agcatggtga tttttggcgt cttcaccatc tacgccattc tgagttactc
    93961 caccaactat ctcaccgaaa tgtacggcat gtcgctggtg gcggcgagct acatggggat
    94021 tgtgatcaac aaaatattcc gcgcgctgtg tggtccactt ggcggcatta tcaccaccta
    94081 cagtaaagtg aaatccccta cccgcgtaat tcaaatcctt tccatcatcg gcctgctggc
    94141 actgactgcc ctgcttgtta ccaactctaa cccgcaatcg gtcgctatgg ggattggcct
    94201 gattttacta ctgggattca cctgctacgc ctcacgtgga ctgtactggg cctgccccgg
    94261 cgaagcgaga acaccgtctt acattatggg caccacggta ggtatttgtt cggtgattgg
    94321 attcctgccg gatgtcttcg tttacccgat tatcggccac tggcaagaca ccctgcccgc
    94381 tgcagaagcc taccgcaaca tgtggctaat gggcatggcc gcgcttgcca tggtgatcat
    94441 ctttaccttt ttgctgttcc aaaaaattcg tactgctgat agcgcccccg caatggctag
    94501 cagcaagtaa gccaggaaaa ttacaggaga aaaatcatgt cgaaaaaata catcataggg
    94561 attgatggcg gaagtcagag cacaaaagtg gtgatgtacg atctggaagg taatgtggtt
    94621 tgcgaaggca aaggcttatt gcagccgatg cacacgccag atgccgatac cgcagaacat
    94681 cctgacgacg atttatgggc atcattatgt tttgccggtc acgatttgat gagtcagttt
    94741 gccggaaata aagaagatat tgtcggtatt ggtctgggat ccatccgttg ctgccgtgcg
    94801 ttattgaaag ccgatggcac gccagctgcg ccgttgatta gctggcagga tgcacgcgtt
    94861 acacgccctt acgaacatac gaatcctgac gtggcatatg tcacctcttt ttcaggttat
    94921 ctgacgcatc gcttaaccgg cgagtttaaa gacaatatcg ccaactattt tggtcagtgg
    94981 ccggtggatt ataagacctg ggcatggagt gaagatgccg cagtcatgga gaagtttaat
    95041 atcccccgtc atatgctgtt tgatgtgcaa atgccgggca ctgttcttgg gcatatcact
    95101 cctcaagccg cgctggcgac acatttccca gctgggctgc cggttgtttg taccaccagt
    95161 gataaaccgg tagaagctct gggagccgga ttactggatg atgaaacggc ggtgatttct
    95221 cttggcacct acatcgcgct gatgatgaac ggtaaagcac tgccgaaaga tccggtggcg
    95281 tactggccga ttatgtcttc tattccgcaa acattgctgt atgaaggtta cggtattcgc
    95341 aaaggcatgt ggacggtgag ctggctgcgc gacatgttag gcgagtcgtt aattcaggat
    95401 gccaaagcac aggatctttc accggaagat ttgctcaaca aaaaagcgtc ttgtgtgccg
    95461 cctggctgta atggtctgat gacggtgctg gactggctga ccaatccgtg ggaaccatac
    95521 aaacgcggga ttatgatcgg ctttgattcc agcatggatt acgcatggat atatcgttcg
    95581 atactggaaa gcgtggcgct gacgctgaag aacaattacg acaatatgtg taatgaaatg
    95641 aatcactttg caaagcatgt gatcattact ggcggcggtt cgaacagcga tctgtttatg
    95701 cagatttttg ccgacgtgtt caaccttccg gcacgccgta acgccattaa tggttgtgca
    95761 agtctggggg cagcgatcaa tacggcggta ggtctggggc tatacccgga ttacgcaacg
    95821 gctgtcgaca aaatggttcg cgtgaaagat atctttatgc ctgttgagag caacgccaaa
    95881 cgctacgacg cgatgaataa aggcattttc aaagacctaa ccaagcacac tgatgtgatc
    95941 ctgaaaaaat cgtatgaagt gatgcatggt gagctgggga atgaagattc gatccagagc
    96001 tggtcgaatg cgtaagtgag gaagaccggg cgggaaactg cccggcctga acatacctga
    96061 atggttatcc ccgctgacgc ggggaacata agttcgacaa cttaaaaaat gataacaagt
    96121 ccggtttatc cccgctgatg cagggaacat aataaaaact ttaactagtt cgtttatccc
    96181 tgttgttaca aggaatatta actacactcg atgtctttag aataaaagac aatacgaatc
    96241 gcactttatc aattttcact taaagtatga actggatatc tttattcata agaactattc
    96301 atcaacagcg tatagaggcg gttatgtaaa accactcatt agcctcaaaa caaagacaaa
    96361 cttccagatt tattacttaa tcaatgaata acaag
//
LOCUS       DADXDL010000007        95433 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.007, whole genome shotgun sequence.
ACCESSION   DADXDL010000007 DADXDL010000000
VERSION     DADXDL010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 95433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 95433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..95433
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.007"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            188..511
                     /gene="iraM"
                     /locus_tag="IRB70_000638"
     CDS             188..511
                     /gene="iraM"
                     /locus_tag="IRB70_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HBC0630587.1"
                     /translation="MKWIVIDTVIQPTCGISFSAIWGDMKMIIWYQSTIFLPPGRIFT
                     PVKSGIILKDKEYPITIYNIAPFNKDLWSLLKSSQECPPGESKITNKCLHNSCIIKIC
                     PYGLK"
     gene            complement(614..1864)
                     /gene="icd"
                     /locus_tag="IRB70_000639"
     CDS             complement(614..1864)
                     /gene="icd"
                     /locus_tag="IRB70_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000444467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent isocitrate dehydrogenase"
                     /protein_id="HBC0630588.1"
                     /translation="MESKVVVPAQGKKITLQNGKLNVPENPIIPYIEGDGIGVDVTPA
                     MLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAETLDLIREYRVAIKGP
                     LTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTDMVIFRENSEDIY
                     AGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKRLVRAAIEYAI
                     ANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVKNPNTGKEIV
                     IKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAAQVGGIGIAPGANIGDECAL
                     FEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAINAKTVTYD
                     FERLMEGAKLLKCSEFGDAIIKNM"
     gene            2444..2893
                     /locus_tag="IRB70_000640"
     CDS             2444..2893
                     /locus_tag="IRB70_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000381622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630589.1"
                     /translation="MDTTEERNGTYFYRGHPNLSKIELLNVIFLEEFCKELGIDSVSG
                     AAILSGQPWLGTRAKPQGATLGTSVVSKYARILMRDARMPFGISVHTPVGVRMQKSNK
                     LAAIIARWVPWIGWASLSMSLYRVSTRTQEKYNLIAKPQDRIKWTSF"
     gene            2878..3228
                     /locus_tag="IRB70_000641"
     CDS             2878..3228
                     /locus_tag="IRB70_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1493 family protein"
                     /protein_id="HBC0630590.1"
                     /translation="MDFLLMATTITDEVLALFRDEIPGYQDDHGKEIPLELDSDLFDY
                     PRDDLEDAIRKYKERFGINLDNLDWSLYLPWESAPLLQRWFKLKREEVETTRLPLTVR
                     MFAESAEAGKWLYQ"
     gene            3561..4199
                     /gene="rluE"
                     /locus_tag="IRB70_000642"
     CDS             3561..4199
                     /gene="rluE"
                     /locus_tag="IRB70_000642"
                     /EC_number="5.4.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2457) synthase RluE"
                     /protein_id="HBC0630591.1"
                     /translation="MKYFSDSKSSFRKKQVSRLNSQHSTKRKPENQPTRVILFNKPYD
                     VLPQFTDEAGRKTLKEFIPVQGVYAAGRLDRDSEGLLVLTNNGALQARLTQPGKRTGK
                     IYYVQVEGIPTQDALEALRNGVTLNDGPTLPAGVELVDEPAWLWPRNPPIRERKSIPT
                     SWLKITLYEGRNRQVRRMTAHVGFPTLRLIRYAMGDYSLDNLANGEWRDATD"
     gene            4209..4670
                     /gene="nudJ"
                     /locus_tag="IRB70_000643"
     CDS             4209..4670
                     /gene="nudJ"
                     /locus_tag="IRB70_000643"
                     /EC_number="3.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase NudJ"
                     /protein_id="HBC0630592.1"
                     /translation="MFKPHVTVACVVHAEGKFLVVEETINGKALWNQPAGHLEADETL
                     VEAAARELWEETGISAQPQHFIRMHQWIAPDKTPFLRFLFAIELEQICPTQPHDSDID
                     CCRWVSAEEILQASNLRSPLVAESIRCYQSGQRYPLEMIGDFNWPFTKGVI"
     gene            4724..5830
                     /gene="mnmA"
                     /locus_tag="IRB70_000644"
     CDS             4724..5830
                     /gene="mnmA"
                     /locus_tag="IRB70_000644"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBC0630593.1"
                     /translation="MSETAKKVIVGMSGGVDSSVSAWLLQQQGYQVEGLFMKNWEEDD
                     GEEYCTAAADLADAQAVCDKLGIELHTVNFAAEYWDNVFELFLAEYKAGRTPNPDILC
                     NKEIKFKAFLEFAAEDLGADYIATGHYVRRADVDGKSRLLRGLDSNKDQSYFLYTLSH
                     EQIAQSLFPVGELEKPQVRKIAEDLGLVTAKKKDSTGICFIGERKFREFLGRYLPAQP
                     GKIITVDGDEIGEHQGLMYHTLGQRKGLGIGGTKDGTEEPWYVVDKDVENNILIVAQG
                     HEHPRLMSVGLIAQQLHWVDREPFTGTMRCTVKTRYRQTDIPCTVKALDDDRIEVIFD
                     EPVAAVTPGQSAVFYNGEVCLGGGIIEQRLPLPV"
     gene            5866..6507
                     /gene="hflD"
                     /locus_tag="IRB70_000645"
     CDS             5866..6507
                     /gene="hflD"
                     /locus_tag="IRB70_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high frequency lysogenization protein HflD"
                     /protein_id="HBC0630594.1"
                     /translation="MAKNYYDITLALAGICQSARLVQQLAHQGHCDGDALHVSLNSII
                     DMNPSSTLAVFGGSEANLRVGLETLLGVLNASSRQGLNAELTRYTLSLMVLERKLSSA
                     KGALDTLGNRINGLQRQLEHFDLQSETLMSAMAAIYVDVISPLGPRIQVTGSPAVLQS
                     PQVQAKVRATLLAGIRAAVLWHQVGGGRLQLMFSRNRLTTQAKQILAHLTPEL"
     gene            6511..7881
                     /gene="purB"
                     /locus_tag="IRB70_000646"
     CDS             6511..7881
                     /gene="purB"
                     /locus_tag="IRB70_000646"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002950897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBC0630595.1"
                     /translation="MELSSLTAVSPVDGRYGDKVSALRGIFSEYGLLKFRVQVEVRWL
                     QKLAAHAAIKEVPAFAADAIGYLDAIVASFSEEDAARIKTIERTTNHDVKAVEYFLKE
                     KVAEIPELHAVSEFIHFACTSEDINNLSHALMLKTARDEVILPYWRQLIDGIKDLAAQ
                     YRDIPLLSRTHGQPATPSTIGKEMANVAYRMERQYRQLNQVEILGKINGAVGNYNAHI
                     AAYPEVDWHQFSEEFVTSLGIQWNPYTTQIEPHDYIAELFDCVARFNTILIDFDRDVW
                     GYIALNHFKQKTIAGEIGSSTMPHKVNPIDFENSEGNLGLSNAVLQHLASKLPVSRWQ
                     RDLTDSTVLRNLGVGIGYALIAYQSTLKGVSKLEVNRDHLLDELDHNWEVLAEPIQTV
                     MRRYGIEKPYEKLKELTRGKRVDAEGMKLFIDGLALPEEEKARLKAMTPANYIGRAIT
                     MVDELK"
     gene            8050..8721
                     /gene="phoP"
                     /locus_tag="IRB70_000647"
     CDS             8050..8721
                     /gene="phoP"
                     /locus_tag="IRB70_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator PhoP"
                     /protein_id="HBC0630596.1"
                     /translation="MRVLVVEDNALLRHHLKVQIQDAGHQVDDAEDAKEADYYLNEHL
                     PDIAIVDLGLPDEDGLSLIRRWRSNDVSLPILVLTARESWQDKVEVLSAGADDYVTKP
                     FHIEEVMARMQALMRRNSGLASQVISLPPFQVDLSRRELSINDEVIKLTAFEYTIMET
                     LIRNNGKVVSKDSLMLQLYPDAELRESHTIDVLMGRLRKKIQAQYPQEVITTVRGQGY
                     LFELR"
     gene            8721..10181
                     /gene="phoQ"
                     /locus_tag="IRB70_000648"
     CDS             8721..10181
                     /gene="phoQ"
                     /locus_tag="IRB70_000648"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PhoQ"
                     /protein_id="HBC0630597.1"
                     /translation="MKKLLRLFFPLSLRVRFLLATAAVVLVLSLAYGMVALIGYSVSF
                     DKTTFRLLRGESNLFYTLAKWENNKLHVELPENIDKQSPTMTLIYDENGQLLWAQRDV
                     PWLMKMIQPDWLKSNGFHEIEADVNDTSLLLSGDHSIQQQLQEVREDDDDAEMTHSVA
                     VNVYPATSRMPKLTIVVVDTIPVELKSSYMVWSWFIYVLSANLLLVIPLLWVAAWWSL
                     RPIEALAKEVRELEEHNRELLNPATTRELTSLVRNLNRLLKSERERYDKYRTTLTDLT
                     HSLKTPLAVLQSTLRSLRSEKMSVSDAEPVMLEQISRISQQIGYYLHRASMRGGTLLS
                     RELHPVAPLLDNLTSALNKVYQRKGVNISLDISPEISFVGEQNDFVEVMGNVLDNACK
                     YCLEFVEISARQTDEHLYIVVEDDGPGIPLSKREVIFDRGQRVDTLRPGQGVGLAVAR
                     EITEQYEGKIVAGESMMGGARMEVIFGRQHSAPKDE"
     gene            10257..11378
                     /gene="roxA"
                     /locus_tag="IRB70_000649"
                     /gene_synonym="ycfD"
     CDS             10257..11378
                     /gene="roxA"
                     /locus_tag="IRB70_000649"
                     /gene_synonym="ycfD"
                     /EC_number="1.14.11.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309600.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[50S ribosomal protein L16]-arginine
                     3-hydroxylase"
                     /protein_id="HBC0630598.1"
                     /translation="MEYQLTLNWPDFLERHWQKRPVVLKRGFNNFIDPISPDELAGLA
                     MESEVDSRLVSHQDGKWQVSHGPFESYDHLGETNWSLLVQAVNHWHEPTAALMRPFRE
                     LPDWRIDDLMISFSVPGGGVGPHLDQYDVFIIQGTGRRRWRVGEKLQMKQHCPHPDLL
                     QVDPFEAIIDEELEPGDILYIPPGFPHEGYALENAMNYSVGFRAPNTRELISGFADYV
                     LQRELGGNYYSDPDVPPRAHPADVLPQEMDKLREMMLELINQPEHFKQWFGEFISQSR
                     HELDIAPPEPPYQPDEIYDALKQGDVLVRLGGLRVLRIGDDVYANGEKIDSPHRPALD
                     ALASNIALTAENFGDALEDPSFLAMLAALVNSGYWFFEG"
     gene            complement(11427..12653)
                     /gene="pepT"
                     /locus_tag="IRB70_000650"
     CDS             complement(11427..12653)
                     /gene="pepT"
                     /locus_tag="IRB70_000650"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBC0630599.1"
                     /translation="MDKLLERFLNYVSLDTQSKAGVRQVPSTEGQWKLLHLLKEQLEE
                     MGLINVTLSEKGTLMATLPANVPGDIPAIGFISHVDTSPDCSGKNVNPQIVENYRGGD
                     IALGIGDEVLSPVMFPVLHQLLGQTLITTDGKTLLGADDKAGIAEIMTALAVLQQKNI
                     PHGDIRVAFTPDEEVGKGAKHFDVDAFDARWAYTVDGGGVGELEFENFNAASVNIKIV
                     GNNVHPGTAKGVMVNALSLAARIHAEVPADESPEMTEGYEGFYHLASMKGTVERADMH
                     YIIRDFDRKQFEARKRKMMEIAKKVGKGLHPDCYIELVIEDSYYNMREKVVEHPHILD
                     IAQQAMRDCDIEPELKPIRGGTDGAQLSFMGLPCPNLFTGGYNYHGKHEFVTLEGMEK
                     AVQVIVRIAELTAQRK"
     gene            12903..14039
                     /gene="potA"
                     /locus_tag="IRB70_000651"
     CDS             12903..14039
                     /gene="potA"
                     /locus_tag="IRB70_000651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     ATP-binding protein PotA"
                     /protein_id="HBC0630600.1"
                     /translation="MGQSKKLNKQPSSLSPLVQLAGIRKCFDGKEVIPQLDLTINNGE
                     FLTLLGPSGCGKTTVLRLIAGLETVDSGRIMLDNEDITHVPAENRYVNTVFQSYALFP
                     HMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLETFAQRKPHQLSGGQQQRVAIAR
                     AVVNKPRLLLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRI
                     VVMRDGRIEQDGTPREIYEEPKNLFVAGFIGEINMFNATVIERLDEQRVRANVEGREC
                     NIYVNFAVEPGQKLHVLLRPEDLRVEEINDDNHAEGLIGYVRERNYKGMTLESVVELE
                     NGKMVMVSEFFNEDDPDFDHSLDQKMAINWVESWEVVLADEEHK"
     gene            14023..14880
                     /gene="potB"
                     /locus_tag="IRB70_000652"
     CDS             14023..14880
                     /gene="potB"
                     /locus_tag="IRB70_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000799378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotB"
                     /protein_id="HBC0630601.1"
                     /translation="MKNTSKFQNVVIVTIVGWLVLFVFLPNLMIIGTSFLTRDDASFV
                     KMVFTLDNYTRLLDPLYFEVLLHSLNMALIATLACLVLGYPFAWFLAKLPHKVRPLLL
                     FLLIVPFWTNSLIRIYGLKIFLSTKGYLNEFLLWLGVIDTPIRIMFTPSAVIIGLVYI
                     LLPFMVMPLYSSIEKLDKPLLEAARDLGASKLQTFIRIIIPLTMPGIIAGCLLVMLPA
                     MGLFYVSDLMGGAKNLLIGNVIKVQFLNIRDWPFGAATSITLTIVMGLMLLVYWRASR
                     LLNKKVELE"
     gene            14877..15671
                     /gene="potC"
                     /locus_tag="IRB70_000653"
     CDS             14877..15671
                     /gene="potC"
                     /locus_tag="IRB70_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter permease
                     PotC"
                     /protein_id="HBC0630602.1"
                     /translation="MIGRLLRGGFMTAIYAYLYIPIIILIVNSFNSSRFGINWQGFTT
                     KWYSLLMNNDSLLQAAQHSLTMAVFSATFATLIGSLTAVALYRYRFRGKPFVSGMLFV
                     VMMSPDIVMAISLLVLFMLLGIQLGFWSLLFSHITFCLPFVVVTVYSRLKGFDVRMLE
                     AAKDLGASEFTILRKIILPLAMPAVAAGWVLSFTLSMDDVVVSSFVTGPSYEILPLKI
                     YSMVKVGVSPEVNALATILLVLSLVMVIASQLIARDKTKGNTGDVK"
     gene            15668..16714
                     /gene="potD"
                     /locus_tag="IRB70_000654"
     CDS             15668..16714
                     /gene="potD"
                     /locus_tag="IRB70_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotD"
                     /protein_id="HBC0630603.1"
                     /translation="MKKWSRHLLAAGALALGMSAAHADDNNTLYFYNWTEYVPPGLLE
                     QFTKETGIKVIYSTYESNETMYAKLKTYKDGAYDLVVPSTYYVDKMRKEGMIQKIDKS
                     KLTNFSNLDPDMLNKPFDPNNDYSIPYIWGATAIGVNGDAVDPKSVTSWADLWKPEYK
                     GSLLLTDDAREVFQMALRKLGYSGNTTDPKEIEAAYNELKKLMPNVAAFNSDNPANPY
                     MEGEVNLGMIWNGSAFVARQSGTPIDVVWPKEGGIFWMDSLAIPANAKNKEGALKLIN
                     FLLRPDVAKQVAETIGYPTPNLAARKLLSPEVANDKTLYPDAETIKNGEWQNDVGVAS
                     SIYEEYYQKLKAGR"
     gene            16772..17233
                     /locus_tag="IRB70_000655"
     CDS             16772..17233
                     /locus_tag="IRB70_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3592 domain-containing protein"
                     /protein_id="HBC0630604.1"
                     /translation="MSQDSKVFFRIFFGIGLVLILISVVIFYNQFTYSKDAIHTEGVI
                     VDTVWHSSHSHRTGKNGSWYPVVAFRPTPDYTLIFNSSIGSDFYEDSEGDKVNVYYSP
                     GHPEKAEINNPWVNFFKWGFIGIMGVIFIAVGLLISMPSSKKTRRKRKSRP"
     gene            17230..18018
                     /locus_tag="IRB70_000656"
     CDS             17230..18018
                     /locus_tag="IRB70_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBC0630605.1"
                     /translation="MKKIMILLSLLMFLPLTAISKPLIPIMKTLFTDVTGTVPDAEEI
                     AHKAELFRQQTGVVPFIVVLPDINNEASLRQNGKAMLAHAASSMSNVKGSVLLLFTTR
                     EPRLIMITNGQVESSMDDKHLGLLVENHTLAYLHVDLWYQGINNALAVLQAQILKQPT
                     PPLTYYPHPGQQQENDPPGSTTTLGLFAWAVAFIVFTAFFNYTTRLNYALKFAVAMTV
                     ANMGYQALCLYIDNSFAITRISPLWAGLIGVCTFIAALLLTSKR"
     gene            complement(18156..18977)
                     /gene="cobB"
                     /locus_tag="IRB70_000657"
     CDS             complement(18156..18977)
                     /gene="cobB"
                     /locus_tag="IRB70_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBC0630606.1"
                     /translation="MLSRRGHRLSRFRKNKRRLRERLRQRIFFRDKVVPEAMEKPRVL
                     VLTGAGISAESGIRTFRAADGLWEEHRVEDVATPEGFDRDPELVQAFYNARRRQLQQP
                     EIQPNAAHLALAKLQDALGDRFLLVTQNIDNLHERAGNTNVIHMHGELLKVRCSQSGQ
                     VLDWTGDVTPEDKCHCCQFPAPLRPHVVWFGEMPLGMDEIYMALSMADIFIAIGTSGH
                     VYPAAGFVHEAKLHGAHTVELNLEPSQVGNEFAEKYYGPASQVVPEFVEKLLKGL"
     gene            complement(18993..19904)
                     /gene="nagK"
                     /locus_tag="IRB70_000658"
     CDS             complement(18993..19904)
                     /gene="nagK"
                     /locus_tag="IRB70_000658"
                     /EC_number="2.7.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine kinase"
                     /protein_id="HBC0630607.1"
                     /translation="MYYGFDIGGTKIALGVFDSGRQLQWEKRVPTPRDSYDAFLDAVC
                     ELVAEADQRFGCKGSVGIGIPGMPETEDGTLYAANVPAASGKPLRADLSARLDRDVRL
                     DNDANCFALSEAWDDEFTQYPLVMGLILGTGVGGGLIFNGKPITGKSYITGEFGHMRL
                     PVDALTMMGLDFPLRRCGCGQHGCIENYLSGRGFAWLYQHYYHQPLQAPEIIALYDQG
                     DEQARAHVERYLDLLAVCLGNILTIVDPDLVVIGGGLSNFPAITTQLADRLPRHLLPV
                     ARVPRIERARHGDAGGMRGAAFLHLTD"
     gene            complement(19933..21177)
                     /gene="lolE"
                     /locus_tag="IRB70_000659"
     CDS             complement(19933..21177)
                     /gene="lolE"
                     /locus_tag="IRB70_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolE"
                     /protein_id="HBC0630608.1"
                     /translation="MAMPLSLLIGLRFSRGRRRGGMVSLISVISTIGIALGVAVLIVG
                     LSAMNGFERELNNRILAVVPHGEIEAVDQPWTNWQEALDNVQKVPGIAAAAPYINFTG
                     LVESGANLRAIQVKGVNPQQEQRLSALPSFVQGDAWRNFKAGEQQIIIGKGVADALKV
                     KQGDWVSIMIPNSNPEHKLMQPKRVRLHVAGILQLSGQLDHSFAMIPLADAQQYLDMG
                     SSVSGIALKMTDVFNANKLVRDAGEVTNSYVYIKSWIGTYGYMYRDIQMIRAIMYLAM
                     VLVIGVACFNIVSTLVMAVKDKSGDIAVLRTLGAKDGLIRAIFVWYGLLAGLFGSLCG
                     VIIGVVVSLQLTPIIERIEKLIGHQFLSSDIYFIDFLPSELHWLDVFYVLVTALLLSL
                     LASWYPARRASNIDPARVLSGQ"
     gene            complement(21177..21878)
                     /gene="lolD"
                     /locus_tag="IRB70_000660"
     CDS             complement(21177..21878)
                     /gene="lolD"
                     /locus_tag="IRB70_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309522.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter
                     ATP-binding protein LolD"
                     /protein_id="HBC0630609.1"
                     /translation="MNKILLQCDNLCKRYQEGSVQTDVLHNVSFSVGEGEMMAIVGSS
                     GSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAAKAELRNQKLGFIYQFHHLLPDF
                     TALENVAMPLLIGKKKPAEINSRALEMLKAVGLEHRANHRPSELSGGERQRVAIARAL
                     VNNPRLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAKRMSRQLEM
                     RDGRLTAELSLMGAE"
     gene            complement(21871..23070)
                     /gene="lolC"
                     /locus_tag="IRB70_000661"
     CDS             complement(21871..23070)
                     /gene="lolC"
                     /locus_tag="IRB70_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004976588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein-releasing ABC transporter permease
                     subunit LolC"
                     /protein_id="HBC0630610.1"
                     /translation="MYQPVALFIGLRYMRGRAADRFGRFVSWLSTIGITLGVMALVTV
                     LSVMNGFERELQNNILGLMPQAILSSEHGSLNPQQLPETAVKLDGVNRVAPITTGDVV
                     LQSARSVAVGVMLGIDPAQKDPLTPYLVNVKQTDLEPGKYNVILGEQLASQLGVNRGD
                     QIRVMVPSASQFTPMGRIPSQRLFNVIGTFAANSEVDGYEMLVNIEDASRLMRYPAGN
                     ITGWRLWLDEPLKVDSLSQQKLPEGSKWQDWRDRKGELFQAVRMEKNMMGLLLSLIVA
                     VAAFNIITSLGLMVMEKQGEVAILQTQGLTPRQIMMVFMVQGASAGIIGAILGAALGA
                     LLASQLNNLMPIIGVLLDGAALPVAIEPLQVIVIALVAMAIALLSTLYPSWRAAATQP
                     AEALRYE"
     gene            23331..24404
                     /locus_tag="IRB70_000662"
     CDS             23331..24404
                     /locus_tag="IRB70_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HBC0630611.1"
                     /translation="MKQKELWINQIKGLCICLVVIYHSVITFYPHLTTFQHPLSEVLS
                     KCWIYFNLYLAPFRMPVFFFISGYLIRRYIDSVPWGNCLDKRIWNIFWVLALWGVVQW
                     LALSALNQWLAPERDLSNASNAAYADSTGEFLHGMITASTSLWYLYALIVYFVVCKIF
                     SRLALPLFALFVLMSVAVNFVPTPWWGMNSVIRNLPYYSLGAWFGATLMTCVKEVPLR
                     RHLLMASLLTVLAVGAWLCTISLLLSLVSIVVIIKLFYQYEQRFGMRSTSLLNVIGSN
                     TIAIYTTHRILVEIFSLTLLAQMNAARLSPQVELTLLLVYPFVSLFICTVAGLLVRKL
                     SQRAFSDLLFSPPSLPAAVSYSR"
     gene            24532..27978
                     /gene="mfd"
                     /locus_tag="IRB70_000663"
     CDS             24532..27978
                     /gene="mfd"
                     /locus_tag="IRB70_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBC0630612.1"
                     /translation="MPEQYRYTLPVKAGEQRLLGELTGAACATLVAEIAERHTGPVVL
                     IAPDMQNALRLHDEISQFTDQMVMNLADWETLPYDSFSPHQDIISSRLSTLYQLPTMQ
                     RGVLIVPVNTLMQRVCPHSFLHGHALVMKKGQRLSRDALRTQLDSAGYRHVDQVMEHG
                     EYATRGALLDLFPMGSELPYRLDFFDDEIDSLRVFDVDSQRTLEEVEEINLLPAHEFP
                     TDKAAIELFRSQWRDTFEVKRDPEHIYQQVSKGTLPAGIEYWQPLFFSEPLPPLFSYF
                     PANTLLVNTGDLENSAERFQTDTLARFENRGVDPMRPLLPPQSLWLRVDDLFSELKNW
                     PRVQLKTEHLPTKAANANLGFQKLPDLAVQAQQKAPLDALRKFLESFDGPVVFSVESE
                     GRREALGELLARIKIAPQRIMRLDEASDRGRYLMIGAAEHGFVDTVRNLALICESDLL
                     GERVARRRQDSRRAINPDTLIRNLAELHIGQPVVHLEHGVGRYAGMTTLEAGGITGEY
                     LMLTYANDAKLYVPVSSLHLISRYAGGAEENAPLHKLGGDAWSRARQKAAEKVRDVAA
                     ELLDIYAQRAAKEGYAFKHDREQYQLFCDSFPFETTPDQAQAINAVLSDMCQPLAMDR
                     LVCGDVGFGKTEVAMRAAFLAVDNHKQVAVLVPTTLLAQQHYDNFRDRFANWPVRIEM
                     ISRFRSAKEQTQILAEVAEGKIDILIGTHKLLQNDVKFKDLGLLIVDEEHRFGVRHKE
                     RIKAMRANVDILTLTATPIPRTLNMAMSGMRDLSIIATPPARRLAVKTFVREYDSLVV
                     REAILREILRGGQVYYLYNDVENIQKAAERLAELVPEARIAIGHGQMRERELERVMND
                     FHHQRFNVLVCTTIIETGIDIPTANTIIIERADHFGLAQLHQLRGRVGRSHHQAYAWL
                     LTPHPKAMTTDAQKRLEAIASLEDLGAGFALATHDLEIRGAGELLGEEQSGSMETIGF
                     SLYMELLENAVDALKAGREPSLEDLTSQQTEVELRMPSLLPDDFIPDVNTRLSFYKRI
                     ASAKTENELEEIKVELIDRFGLLPDPARTLLDIARLRQQAQKLGIRKLEGNEKGGVIE
                     FAEKNHVNPAWLIGLLQKQPQHYRLDGPTRLKFIQDLSERKTRIEWVRQFMRELEENA
                     IA"
     gene            28121..29083
                     /gene="ldtC"
                     /locus_tag="IRB70_000664"
     CDS             28121..29083
                     /gene="ldtC"
                     /locus_tag="IRB70_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase LdtC"
                     /protein_id="HBC0630613.1"
                     /translation="MMIKTRFSRWLTFFTFAAAVALALPAKANTWPLPPAGSRLVGEN
                     KFHVVENDSGSLEAIAKKYNVGFLALLQANPGVDPYVPRAGSVLTIPLQTLLPDAPRE
                     GIVINIAELRLYYYPPGKNSVTVYPIGIGQLGGDTLTPTMVTTVSDKRANPTWTPTAN
                     IRARYKAQGIELPAVVPAGPDNPMGHHAIRLAAYGGVYLLHGTNADFGIGMRVSSGCI
                     RLRDDDIKTLFSQVTPGTKVNIINIPIKVSAEPNGARLVEVHQPLSEKIDDDPQLLPI
                     TLNSAMQSFKDAAQTDAEVMQHVMDVRSGMPVDVRRHQVSPQTL"
     gene            complement(29167..29424)
                     /gene="bhsA"
                     /locus_tag="IRB70_000665"
     CDS             complement(29167..29424)
                     /gene="bhsA"
                     /locus_tag="IRB70_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple stress resistance protein BhsA"
                     /protein_id="HBC0630614.1"
                     /translation="MKNVKTLIAAAILSSMSFASFAAVEVQSTPEGQQKVGTISANAG
                     TNLGSLEEQLAQKADEMGAKSFRITSVTGPNTLHGTAVIYK"
     gene            29665..30297
                     /gene="comR"
                     /locus_tag="IRB70_000666"
     CDS             29665..30297
                     /gene="comR"
                     /locus_tag="IRB70_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415629.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family copper-responsive transcriptional
                     repressor ComR"
                     /protein_id="HBC0630615.1"
                     /translation="MATDSTQCIKKSRGRPKVFDRDAALDKAMKLFWQHGYEATSLAD
                     LVEATGAKAPTLYAEFTNKEGLFRAVLDRYIDRFAAKHEAQLFCEEKSVESALADYFA
                     AIANCFTSKDTPAGCFMINNCTTLSPDSGDIANTLKSRHAMQERTLQQFLCQRQARGE
                     IPTHCDVTHLAEFLNCIIQGMSISAREGASQEKLMQIARTTLRLWPELLK"
     gene            complement(30359..30898)
                     /locus_tag="IRB70_000667"
     CDS             complement(30359..30898)
                     /locus_tag="IRB70_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HBC0630616.1"
                     /translation="MNKSMLAGIGIGVAAALGVAAVASLNVFERGPQYAQVVSATPIK
                     ETVKTPRQECRNVTVTHRRPVQDENRITGSVLGAVAGGVIGHRFGGGRGKDVATVVGA
                     LGGGYAGNQIQGSLQESDTYTTTQQRCKTVYDKSEKMLGYDVTYKIGDQQGKIRMDRD
                     PGTQIPLDSNGQLILNNKA"
     gene            complement(31125..32429)
                     /gene="ndh"
                     /locus_tag="IRB70_000668"
     CDS             complement(31125..32429)
                     /gene="ndh"
                     /locus_tag="IRB70_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017384716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone dehydrogenase"
                     /protein_id="HBC0630617.1"
                     /translation="MTTPLKKIVIVGGGAGGLEMATQLGHKLGRKKKAKITLVDRNHS
                     HLWKPLLHEVATGSLDEGVDALSYLAHARNHGFQFQLGSVIDIDREAKTITIAELRDE
                     KGELLVPERKIAYDTLVMALGSTSNDFNTPGVKENCIFLDNPHQARRFHQEMLNLFLK
                     YSANLGANGKVNIAIVGGGATGVELSAELHNAVKQLHSYGYKGLTNEALNVTLVEAGE
                     RILPALPPRISAAAHSELTKLGVRVLTQTMVTSADEGGLHTKDGEYIEADLMVWAAGI
                     KAPDFLKDIGGLETNRINQLVVEPTLQTTRDPDIYAIGDCASCPRPEGGFVPPRAQAA
                     HQMATCAMNNILAQMNGKPLKSYQYKDHGSLVSLSNFSTVGSLMGNLTRGSMMIEGRI
                     ARFVYISLYRMHQIALHGYFKTGLMMLVGSINRVIRPRLKLH"
     gene            complement(32829..33371)
                     /locus_tag="IRB70_000669"
     CDS             complement(32829..33371)
                     /locus_tag="IRB70_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBC0630618.1"
                     /translation="MIIYLHGFDSNSPGNHEKVLQLQFIDPDVRLISYSTRHPKHDMQ
                     HLLKEVDKMLQLNVDERPLICGVGLGGYWAERIGFLCDIRQVIFNPNLFPYENMEGKI
                     DRPEEYADIATKCVTNFREKNRDRCLVILSRNDEALNSQRTSEELHHYYEIVWDEEQT
                     HKFKNISPHLQRIKAFKTLG"
     gene            complement(33394..34419)
                     /gene="nagZ"
                     /locus_tag="IRB70_000670"
     CDS             complement(33394..34419)
                     /gene="nagZ"
                     /locus_tag="IRB70_000670"
                     /EC_number="3.2.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-N-acetylhexosaminidase"
                     /protein_id="HBC0630619.1"
                     /translation="MGPVMLDVEGYELDAEEREILAHPLVGGLILFTRNYHDPAQLRE
                     LVRQIRAASRNHLVVAVDQEGGRVQRFREGFTRLPAAQSFAALLGMEEGGKLAQEAGW
                     LMASEMIAMDIDISFAPVLDVGHISAAIGERSYHADPEKALAIASRFIDGMHEAGMKT
                     TGKHFPGHGAVTADSHKETPCDPRPQAEIRAKDMSVFSSLIRENKLDAIMPAHVIYSD
                     VDPRPASGSPYWLKTVLRQELGFDGVIFSDDLSMEGAAIMGSYAERGQASLDAGCDMI
                     LVCNNRKGAVSVLDNLSPIKAERVTRLYHKGSFSRQELMDSARWKAISARLNQLHERW
                     QEEKAGH"
     gene            complement(34430..35254)
                     /gene="thiK"
                     /locus_tag="IRB70_000671"
     CDS             complement(34430..35254)
                     /gene="thiK"
                     /locus_tag="IRB70_000671"
                     /EC_number="2.7.1.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine kinase"
                     /protein_id="HBC0630620.1"
                     /translation="MPFRSNNPITRDELLSCFFPQFHPVTTFNSGLSGGSFLIEHQGQ
                     RFVVRQPHDPDAPRFAFLRQYRALSQLPACIAPKPHLYLRDWMVVDYLPGEVKTYLPD
                     TNELAGLLYYLHQQPRFGWRITLLPLLELYWQQSDPVRRTVGWLRMLKRLRKAREPRP
                     LRLSPLHMDVHAGNLVHSASGLKLIDWEYAGDGDIALELAAVWVENTDQHRQLVNDYA
                     TRAKIYPAQLWRQVRRWFPWLLMLKAGWFEYRWRQTGDQQFIRLADDTWRQLLIKQ"
     gene            complement(35235..35876)
                     /gene="lpoB"
                     /locus_tag="IRB70_000672"
     CDS             complement(35235..35876)
                     /gene="lpoB"
                     /locus_tag="IRB70_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoB"
                     /protein_id="HBC0630621.1"
                     /translation="MTKMSRYALITALAMFLAGCVGQREPAPVEEVKPAPEQPAEPQQ
                     PVPTVPSVPTIPQQPGPIEHEDQTAPPAPHIRHYDWNGAMQPMVSKMLGADGVTAGSV
                     LLVDSVNNRTNGSLNAAEATETLRNALANNGKFTLVSAQQLSMAKQQLGLSPQDSLGT
                     RSKAIGIARNVGAHYVLYSSASGNVNAPTLQMQLMLVQTGEIIWSGKGAVSQQ"
     gene            complement(35890..36267)
                     /locus_tag="IRB70_000673"
     CDS             complement(35890..36267)
                     /locus_tag="IRB70_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcfL family protein"
                     /protein_id="HBC0630622.1"
                     /translation="MRKGCFGLVSLALLVLVGCRTHPEIPVNDEQSLVMESSLLAAGI
                     SAEKPVLSTSDIQPSASSTLYNERQEPVTVHYRFYWYDARGLEMHPLERPRSVTIPAH
                     SAVTLYGSANFLGAHKVRLYLYL"
     gene            complement(36270..36629)
                     /gene="hinT"
                     /locus_tag="IRB70_000674"
     CDS             complement(36270..36629)
                     /gene="hinT"
                     /locus_tag="IRB70_000674"
                     /EC_number="3.9.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415621.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleoside phosphoramidase"
                     /protein_id="HBC0630623.1"
                     /translation="MAEETIFSKIIRREIPSDIVYQDDLVTAFRDISPQAPTHILIIP
                     NILIPTVNDVSAEHEQALGRMITVAAKIAEQEGIAEDGYRLIMNTNRHGGQEVYHIHM
                     HLLGGRPLGPMLAHKGL"
     gene            36963..39152
                     /gene="fhuE"
                     /locus_tag="IRB70_000675"
     CDS             36963..39152
                     /gene="fhuE"
                     /locus_tag="IRB70_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric-rhodotorulic acid/ferric-coprogen
                     receptor FhuE"
                     /protein_id="HBC0630624.1"
                     /translation="MLSTQFNRDNQHQAIIKPSLLAGCIALALLPSAAFAAPVTEETV
                     IVEGSATAPDDGENDYNVTSTSAGTKMQMTQRDIPQSVTIVSQQRMEDQQLQTLGEVM
                     ENTLGISKSQADSDRALYYSRGFQIDNYMVDGIPTYFESRWNLGDALSDMALFERVEV
                     VRGATGLMTGTGNPSAAINMVRKHATSREFKGDVSAEYGSWNKERYVADLQSPLTEDG
                     KIRARIVGGYQNNDSWLDRYNSEKTFFSGIVDADLGDLTMLSAGYEYQRIDVNSPTWG
                     GLPRWNTDGSSNSYDRARSTAPDWAYNDKEINKVFMTLKQRFADTWQATLNATHSEVE
                     FDSKMMYVDAYVNKADGMLVGPYSNYGPGFDYVGGTGWNSGKRKVDALDLFADGSYEL
                     FGRQHNLMFGGSYSKQNNRYISSWANIFPDEIGSFYNFNGNFPQTDWSPQSLAQDDTT
                     HMKSLYAATRVTLADPLHLILGARYTNWRVDTLTYSMEKNHTTPYAGLVFDINDNWST
                     YASYTSIFQPQNDRDSSGKYLAPITGNNYELGLKSDWMNSRLTTTLAIFRIEQDNVAQ
                     STGTPIPGSNGETAYKAVDGTVSKGVEFELNGAITDNWQLTFGATRYIAEDNEGNAVN
                     PNLPRSTVKMFTSYRLPVMPELTVGGGVNWQNRVYTDTVTPYGTFRAEQGSYALVDLF
                     TRYQVTKNFSLQGNVNNLFDKTYDTNVEGSIVYGAPRNFSITGTYQF"
     gene            complement(39212..40645)
                     /gene="ptsG"
                     /locus_tag="IRB70_000676"
     CDS             complement(39212..40645)
                     /gene="ptsG"
                     /locus_tag="IRB70_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000475716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIBC"
                     /protein_id="HBC0630625.1"
                     /translation="MFKNAFANLQKVGKSLMLPVSVLPIAGILLGVGSANFSWLPAVV
                     SHVMAEAGGSVFANMPLIFAIGVALGFTNNDGVSALAAVVAYGIMVKTMAVVAPLVLH
                     LPAEEIASKHLADTGVLGGIISGAIAAYMFNRFYRIKLPEYLGFFAGKRFVPIISGLA
                     AIFTGVVLSFIWPPIGSAIQTFSQWAAYQNPVVAFGIYGFIERCLVPFGLHHIWNVPF
                     QMQIGEYTNAAGQVFHGDIPRYMAGDPTAGKLSGGFLFKMYGLPAAAIAIWHSAKPEN
                     RAKVGGIMISAALTSFLTGITEPIEFSFMFVAPILYIIHAILAGLAFPICILLGMRDG
                     TSFSHGLIDFIVLSGNSSKLWLFPIVGIGYAIVYYTIFRVLIKALDLKTPGREDATED
                     AKATGTSEMAPALVAAFGGKENITNLDACITRLRVSVADVSKVDQAGLKKLGAAGVVV
                     AGSGVQAIFGTKSDNLKTEMDEYIRNH"
     gene            complement(40940..41737)
                     /locus_tag="IRB70_000677"
     CDS             complement(40940..41737)
                     /locus_tag="IRB70_000677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBC0630626.1"
                     /translation="MFLVDSHCHLDGLDYESLHKDVDDVLAKAAARDVKFCLAVATTL
                     PGYLHMRDLVGERDNVVFSCGVHPLNQNDPYDVEDLRRLAAEEGVVALGETGLDYYYT
                     PETKVRQQESFIHHIQIGRELNKPVIVHTRDARADTLAILREEKVTDCGGVLHCFTED
                     RETAGKLLDLGFYISFSGIVTFRNAEQLRDAARYVPLDRLLVETDSPYLAPVPHRGKE
                     NQPAMVRDVAEYMAVLKGVAVEELAQVTTDNFARLFHIDASRLQSIR"
     gene            complement(41748..42752)
                     /gene="holB"
                     /locus_tag="IRB70_000678"
     CDS             complement(41748..42752)
                     /gene="holB"
                     /locus_tag="IRB70_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBC0630627.1"
                     /translation="MRWYPWLRPDFEKLVASYQAGRGHHALLIQALPGMGEDALIYAL
                     SRYLLCQQPQGHKSCGHCRGCQLMQAGTHPDYYTLAPEKGKNALGIDAVREVTEKLNE
                     HARLGGAKVVWVTDAALLTDAAANALLKTLEEPPAETWFFLATREPERLLATLRSRCR
                     LHYLAPPPEQYAVTWLSREVTMSQDALLAALRLSAGSPGAALALFQGDNWQARETLCQ
                     ALAYSVPSGDWYSLLAALNHEQAPARLHWLATLLMDALKRHHGAAQVTNVDVPGLVVE
                     LANHLSPSRLQAILGDVCHIREQLMSVTGINRELLITDLLLRIEHYLQPGVVLPVPHL
                     "
     gene            complement(42749..43390)
                     /locus_tag="IRB70_000679"
     CDS             complement(42749..43390)
                     /locus_tag="IRB70_000679"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBC0630628.1"
                     /translation="MRSKYIVIEGLEGAGKTTARNVVVETLEQLGIRDMVFTREPGGT
                     QLAEKLRSLVLDIKSVGDEVITDKAEVLMFYAARVQLVETVIKPALANGTWVIGDRHD
                     LSTQAYQGGGRGIDQHMLATLRDAVLGDFRPDLTLYLDVTPEVGLKRARARGELDRIE
                     QESFDFFNRTRARYLELAAQDKSIHTIDATQPLESVMDAIRTTVTNWVKELDA"
     gene            complement(43380..44402)
                     /gene="yceG"
                     /locus_tag="IRB70_000680"
     CDS             complement(43380..44402)
                     /gene="yceG"
                     /locus_tag="IRB70_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YceG"
                     /protein_id="HBC0630629.1"
                     /translation="MKKVLLIILLLLVVLGIAAGVGVWKVRHLADSKLLIKEETIFTL
                     KPGTGRLALGEQLYADKIINRPRVFQWLLRIEPDLSHFKAGTYRFTPQMTVREMLKLL
                     ESGKEAQFPLRLVEGMRLSDYLKQLREAPYIKHTLSDDKYATVAQALELENPEWIEGW
                     FWPDTWMYTANTTDVALLKRAHKKMVKAVDSAWEGRADGLPYKDKNQLVTMASIIEKE
                     TAVASERDQVASVFINRLRIGMRLQTDPTVIYGMGERYNGKLSRADLETPTAYNTYTI
                     TGLPPGAIATPGADSLKAAAHPAKTPYLYFVADGKGGHTFNTNLASHNKSVQDYLKVL
                     KEKNAQ"
     gene            complement(44405..45214)
                     /gene="pabC"
                     /locus_tag="IRB70_000681"
     CDS             complement(44405..45214)
                     /gene="pabC"
                     /locus_tag="IRB70_000681"
                     /EC_number="4.1.3.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate lyase"
                     /protein_id="HBC0630630.1"
                     /translation="MFLINGHKQESLAVSDRATQFGDGCFTTARVIDGKVSLLSAHIQ
                     RLQDACQRLMISCDFWPQLELEMKTLAAEQQNGVLKVVISRGSGGRGYSTLNSGPATR
                     ILSVTVYPAHYDRLRNEGMTLALSPVRLGRNPHLAGIKHLNRLEQVLIRSHLEQTNAD
                     EALVLDSEGWVTECCAANLFWRKGNVVYTPRLDQAGVNGIMRQFCIRLLAQSSYQLVE
                     VQASLEEALQADEMVICNALMPVMPVRACGDVSFSSATLYEYLAPLCERPN"
     gene            complement(45334..46575)
                     /gene="fabF"
                     /locus_tag="IRB70_000682"
     CDS             complement(45334..46575)
                     /gene="fabF"
                     /locus_tag="IRB70_000682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBC0630631.1"
                     /translation="MSKRRVVVTGLGMLSPVGNTVESTWKALLAGQSGISLIDHFDTS
                     AYATKFAGLVKDFNCEDIISRKEQRKMDAFIQYGIVAGVQAMQDSGLEITEENATRIG
                     AAIGSGIGGLGLIEENHTSLMNGGPRKISPFFVPSTIVNMVAGHLTIMYGLRGPSISI
                     ATACTSGVHNIGHAARIIAYGDADVMVAGGAEKASTPLGVGGFGAARALSTRNDNPQA
                     ASRPWDKERDGFVLGDGAGMLVLEEYEHAKKRGAKIYAELVGFGMSSDAYHMTSPPEN
                     GAGAALAMANALRDAGIEASQIGYVNAHGTSTPAGDKAEAQAVKTIFGEAASRVLVSS
                     TKSMTGHLLGAAGAVESIYSILALRDQAVPPTINLDNPDEGCDLDFVPHEARQVSGME
                     YTLCNSFGFGGTNGSLIFKKI"
     gene            complement(46663..46899)
                     /gene="acpP"
                     /locus_tag="IRB70_000683"
     CDS             complement(46663..46899)
                     /gene="acpP"
                     /locus_tag="IRB70_000683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016535861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBC0630632.1"
                     /translation="MSTIEERVKKIIGEQLGVKQEEVTNNASFVEDLGADSLDTVELV
                     MALEEEFDTEIPDEEAEKITTVQAAIDYINGHQA"
     gene            complement(47110..47844)
                     /gene="fabG"
                     /locus_tag="IRB70_000684"
     CDS             complement(47110..47844)
                     /gene="fabG"
                     /locus_tag="IRB70_000684"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase FabG"
                     /protein_id="HBC0630633.1"
                     /translation="MNFEGKIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQA
                     ISDYLGANGKGMMLNVTDPASIESVLEKIRAEFGEVDILVNNAGITRDNLLMRMKDEE
                     WNDIIETNLSSVFRLSKAVMRAMMKKRHGRIITIGSVVGTMGNGGQANYAAAKAGLIG
                     FSKSLAREVASRGITVNVVAPGFIETDMTRALSDDQRAGILAQVPAGRLGGAQEIANA
                     VAFLASDEAAYITGETLHVNGGMYMV"
     gene            complement(47857..48786)
                     /gene="fabD"
                     /locus_tag="IRB70_000685"
     CDS             complement(47857..48786)
                     /gene="fabD"
                     /locus_tag="IRB70_000685"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBC0630634.1"
                     /translation="MTQFAFVFPGQGSQTVGMLADMAASYPIVEETFAEASAALGYDL
                     WALTQQGPAEELNKTWQTQPALLTASVALYRVWQQQGGKAPAMMAGHSLGEYSALVCA
                     GVIDFADAVRLVEMRGKFMQEAVPEGTGAMAAIIGLDDASIAKACEEAAEGQVVSPVN
                     FNSPGQVVIAGHKEAVERAGAACKAAGAKRALPLPVSVPSHCALMKPAADKLAVELAK
                     ITFNAPTVPVVNNVDVKCETNGDAIRDALVRQLYNPVQWTKSVEYMAAQGVEHLYEVG
                     PGKVLTGLTKRIVDTLTASALNEPSAMAAALEL"
     gene            complement(48802..49755)
                     /gene="fabH"
                     /locus_tag="IRB70_000686"
     CDS             complement(48802..49755)
                     /gene="fabH"
                     /locus_tag="IRB70_000686"
                     /EC_number="2.3.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase III"
                     /protein_id="HBC0630635.1"
                     /translation="MYTKIIGTGSYLPEQVRTNADLEKMVDTSDEWIVTRTGIRERHI
                     AAPNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGIKG
                     CPAFDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDRGTIIIFGDG
                     AGAAVLAASEEPGIISTHLHADGSYGELLTLPNADRVNPENSIHLTMAGNEVFKVAVT
                     ELAHIVDETLAANNLDRSQLDWLVPHQANLRIISATAKKLGMSMDNVVVTLDRHGNTS
                     AASVPCALDEAVRDGRIKPGQLVLLEAFGGGFTWGSALVRF"
     gene            complement(49823..50893)
                     /gene="plsX"
                     /locus_tag="IRB70_000687"
     CDS             complement(49823..50893)
                     /gene="plsX"
                     /locus_tag="IRB70_000687"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415608.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBC0630636.1"
                     /translation="MTRLTLALDVMGGDFGPSVTVPAALQALNSNSQLTLLLVGNPDA
                     ITPLLAKADFEQRSRLQIIPAQSVIASDARPSQAIRASRGSSMRVALELVKEGRAQAC
                     VSAGNTGALMGLAKLLLKPLEGIERPALVTVLPHQQKGKTVVLDLGANVDCDSTMLVQ
                     FAIMGSVLAEEVVEIPNPRVALLNIGEEEVKGLDSIRDASAVLKTIPSINYIGYLEAN
                     ELLTGKTDVLVCDGFTGNVTLKTMEGVVRMFLSLLKSQGEGKKRSWWLLLLKRWLQKS
                     LTRRFSHLNPDQYNGACLLGLRGTVIKSHGAANQRAFAVAIEQAVQAVQRQVPQRIAA
                     RLESVYPAGFELLDGGKSGTLR"
     gene            complement(50974..51147)
                     /gene="rpmF"
                     /locus_tag="IRB70_000688"
     CDS             complement(50974..51147)
                     /gene="rpmF"
                     /locus_tag="IRB70_000688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBC0630637.1"
                     /translation="MAVQQNKPTRSKRGMRRSHDALTAVTSLSVDKTSGEKHLRHHIT
                     ADGYYRGRKVIAK"
     gene            complement(51199..51720)
                     /gene="yceD"
                     /locus_tag="IRB70_000689"
     CDS             complement(51199..51720)
                     /gene="yceD"
                     /locus_tag="IRB70_000689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001174481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA accumulation protein YceD"
                     /protein_id="HBC0630638.1"
                     /translation="MQKVKLPLTLDPVRTAQKRLDYQGIYTPDQVERVAESVVSVDSD
                     VECSMSFAIDNQRLAVLNGDAKVTVTLECQRCGKPFTHQVYTTYCFSPVRSDEQAEAL
                     PEAYEPIEVNEFGEIDLLAMVEDEIILALPVVPVHDSEHCEVSEADMVFGELPEEAQK
                     PNPFAVLASLKRK"
     gene            51919..52503
                     /gene="yceF"
                     /locus_tag="IRB70_000690"
     CDS             51919..52503
                     /gene="yceF"
                     /locus_tag="IRB70_000690"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-methyl-GTP pyrophosphatase"
                     /protein_id="HBC0630639.1"
                     /translation="MPKLILASTSPWRRALLEKLQISFECAAPEVDETPRSDESPRQL
                     VLRLAQEKAQSLASRYPDHLIIGSDQVCVLDGEITGKPLTEENARLQLRKASGNIVTF
                     YTGLALFNSANGHLQTEVEPFDVHFRHLSEAEIDNYVRKEHPLHCAGSFKSEGFGITL
                     FERLEGRDPNTLVGLPLIALCQMLRREGKNPLMG"
     gene            complement(52615..53574)
                     /gene="rluC"
                     /locus_tag="IRB70_000691"
     CDS             complement(52615..53574)
                     /gene="rluC"
                     /locus_tag="IRB70_000691"
                     /EC_number="5.4.99.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(955/2504/2580) synthase
                     RluC"
                     /protein_id="HBC0630640.1"
                     /translation="MKTETPSVKIVAITADEAGQRIDNFLRTQLKGVPKSMIYRILRK
                     GEVRVNKKRIKPEYKLEAGDEVRIPPVRVAEREEEAVSPHLQKVAALADVILYEDDHI
                     LVLNKPSGTAVHGGSGLSFGVIEGLRALRPEARFLELVHRLDRDTSGVLLVAKKRSAL
                     RSLHEQLREKGMQKDYLALVRGQWQSHVKSVQAPLLKNILQSGERIVRVSQEGKPSET
                     RFKVEERYAFATLVRCSPVTGRTHQIRVHTQYAGHPIAFDDRYGDREFDRQLTEAGTG
                     LNRLFLHAAALKFTHPGTGEVMRIEAPMDEGLKRCLQKLRKAR"
     gene            54147..57320
                     /gene="rne"
                     /locus_tag="IRB70_000692"
     CDS             54147..57320
                     /gene="rne"
                     /locus_tag="IRB70_000692"
                     /EC_number="3.1.26.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E"
                     /protein_id="HBC0630641.1"
                     /translation="MKRMLINATQQEELRVALVDGQRLYDLDIESPGHEQKKANIYKG
                     KITRIEPSLEAAFVDYGAERHGFLPLKEIAREYFPANYSAHGRPNIKDVLREGQEVIV
                     QIDKEERGNKGAALTTFISLAGSYLVLMPNNPRAGGISRRIEGDDRTELKEALASLEL
                     PEGMGLIVRTAGVGKSAEALQWDLSFRLKHWEAIKKAAESRPAPFLIHQESNVIVRAF
                     RDYLRQDIGEILIDNPKVLELARQHIAALGRPDFSSKIKLYTGEIPLFSHYQIESQIE
                     SAFQREVRLPSGGSIVIDSTEALTAIDINSARATRGGDIEETAFNTNLEAADEIARQL
                     RLRDLGGLIVIDFIDMTPVRHQRAVENRLREAVRQDRARIQISHISRFGLLEMSRQRL
                     SPSLGESSHHVCPRCSGTGTVRDNESLSLSILRLIEEEALKENTQEVHAIVPVPIASY
                     LLNEKRSAVNAIETRQDGVRCVIVPNDQMETPHYHVLRVRKGEETPTLSYMLPKLHEE
                     AMALPSEEEFAERKRPEQPALATFAMPDVPPAPTPAEPAAPVVAPAPKAAPATPAAPA
                     QPGLLSRFFGALKALFSGGEETKPAEQPAPKAEAKPERQQDRRKPRQNNRRDRNERRD
                     SRSERTEGSDNREENRRNRRQAQQQTAETRESRQQAEVTEKARTTDEQQAPRRERSRR
                     RNDDKRQAQQEAKALNVEEQSVQETEQEERVRPVQPRRKQRQLNQKVRYEQSVAEEAV
                     VAPVVEETVVAEPIVQEAPAPRTELVKVPLPVVAQAAPEQQEENNADNRDNGGMPRRS
                     RRSPRHLRVSGQRRRRYRDERYPTQSPMPLTVACASPELASGKVWIRYPIVRPQDVQV
                     EEQREQEEVQVQPMVTEVPVAAAVEPVVSAPVVEEVAEVVEAPVQVAEPQPEMAETTH
                     PEVIAAAVTEQPQVITESDVAVAQEVAEHAEPVVEPQEETADIEEVAETAEVVVAEPE
                     VVAQPAAPVAAEVETVAAVEPEITVEHNHATAPMTRAPAPEYVPEAPRHSDWQRPTFA
                     FEGKGAAGGHTATHHASAAPARPQPVE"
     gene            57454..57747
                     /locus_tag="IRB70_000693"
     CDS             57454..57747
                     /locus_tag="IRB70_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011092560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1778 domain-containing protein"
                     /protein_id="HBC0630642.1"
                     /translation="MAAANNIPARRESLNLRIKPAERDLIDRAAKARGKNRSEFVLEA
                     ARAAAEEALIEQRIFRIDSDDYQLFLNRLDQPPAPNAALRKTMQTPAPWEQKK"
     gene            57744..58238
                     /locus_tag="IRB70_000694"
     CDS             57744..58238
                     /locus_tag="IRB70_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000613627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBC0630643.1"
                     /translation="MIQAPEPLMARHQFTSFCSGVETMDNWLKQRALKNQLAGASRTF
                     VSCDTYSNVLAYYSLASSAVETYVATGRFRRNMPEPIPVVVLGRLAIDKSLQGQGIGR
                     AMVRDAGLRVLQAAEVIGIRGMLVHALSDQAREFYLRVGFEPSPVDSMILMATLADLQ
                     ECLK"
     gene            complement(58333..59286)
                     /gene="flgL"
                     /locus_tag="IRB70_000695"
     CDS             complement(58333..59286)
                     /gene="flgL"
                     /locus_tag="IRB70_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgL"
                     /protein_id="HBC0630644.1"
                     /translation="MRFSTQMMYQQNMRGITNSQAEWMKYGEQMSTGKRVVNPSDDPI
                     AASQAVVLSQAQAQNSQYTLARTFATQKVSLEESVLSQVTTAIQNAQEKIVYASNGTL
                     SDDDRASLATDIQGLRDQLLNLANTTDGNGRYIFAGYKTESAPFSEEDGKYEGGAESI
                     KQQVDASRSMVIGHTGDKIFDSITSNAVAEPDGSASETNLFAMLDSAIAALKTPVADS
                     EADKETAAAALDKTNRGLKNSLNNVLTVRAELGTQLNELESLDSLGSDRALGQTQQMS
                     DLVDVDWNATISSYIMQQTALQASYKAFTDMQGLSLFQLNK"
     gene            complement(59298..60941)
                     /gene="flgK"
                     /locus_tag="IRB70_000696"
     CDS             complement(59298..60941)
                     /gene="flgK"
                     /locus_tag="IRB70_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-associated protein FlgK"
                     /protein_id="HBC0630645.1"
                     /translation="MSSLINNAMSGLNAAQAALNTASNNISSYNVAGYTRQTTIMAQA
                     NSTLGAGGWVGNGVYVSGVQREYDAFITNQLRAAQTQSSGLTARYEQMSKIDNMLSTS
                     TSSLATQMQDFFTSLQTLVSNAEDPAARQALIGKSEGLVNQFKTTDQYLRDQDKQVNI
                     AIGASVDQINNYAKQIASLNDQISRLTGVGAGASPNNLLDQRDQLVSELNQIVGVEVS
                     VQDGGTYNITMANGYSLVQGSTARQLAAVPSSADPSRTTVAYIDGTAGNIEIPEKLLN
                     TGSLGGILTFRSQDLDQTRNTLGQLALAFAEAFNTQHKAGFDANGDAGEDFFAIGKPA
                     VLQNTKNKGDVAIGATVTDASAVLATDYKISFDNNQWQVTRLASNTTFTVTPDANGKV
                     AFDGLELTFTGTPAVNDSFTLKPVSDAIVNMDVLITDEAKIAMASAEDAGDSDNRNGQ
                     ALLDLQSNSKTVGGAKSFNDAYASLVSDIGNKTATLKTSSATQGNVVTQLSNQQQSIS
                     GVNLDEEYGNLQRFQQYYLANAQVLQTANAIFDALINIR"
     gene            complement(61007..61948)
                     /gene="flgJ"
                     /locus_tag="IRB70_000697"
     CDS             complement(61007..61948)
                     /gene="flgJ"
                     /locus_tag="IRB70_000697"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly peptidoglycan hydrolase FlgJ"
                     /protein_id="HBC0630646.1"
                     /translation="MISDSKLLASAAWDAQSLNELKAKAGEDPAANIRPVARQVEGMF
                     VQMMLKSMRDALPKDGLFSSEHTRLYTSMYDQQIAQQMTAGKGLGLAEMMVKQMTPEQ
                     PLPEESTPAAPMKFPLETVVRYQNQTLSQLVQKAVPRNYDDSLPGDSKAFLAQLSLPA
                     QLASQQSGVPHHLILAQAALESGWGQRQIRRENGEPSYNLFGVKASGNWKGPVTEITT
                     TEYENGEAKKVKAKFRVYSSYLEALSDYVGLLTRNPRYAAVTTAASAEQGAQALQDAG
                     YATDPHYARKLTSMIQQMKSISDKVSKTYSMNIDNLF"
     gene            complement(61948..63045)
                     /gene="flgI"
                     /locus_tag="IRB70_000698"
     CDS             complement(61948..63045)
                     /gene="flgI"
                     /locus_tag="IRB70_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415598.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring protein FlgI"
                     /protein_id="HBC0630647.1"
                     /translation="MIKFLSALILLLVTTAVQAERIRDLTSVQGVRQNSLIGYGLVVG
                     LDGTGDQTTQTPFTTQTLNNMLSQLGITVPTGTNMQLKNVAAVMVTASLPPFGRQGQT
                     IDVVVSSMGNAKSLRGGTLLMTPLKGVDSQVYALAQGNILVGGAGASAGGSSVQVNQL
                     NGGRITNGAVIERELPSQFGVGNALNLQLNEEDFSMAQQIADTINRVRGYGSATALDA
                     RTIQVRVPSGNSSQVRFLADIQNMQVNVTPQDAKVVINSRTGSVVMNREVTLDSCAVA
                     QGNLSVTVNRQANVSQPDTPFGGGQTVVTPQTQIDLRQSGGSLQSVRSSASLNNVVRA
                     LNALGATPMDLMSILQSMQSAGCLRAKLEII"
     gene            complement(63057..63755)
                     /gene="flgH"
                     /locus_tag="IRB70_000699"
     CDS             complement(63057..63755)
                     /gene="flgH"
                     /locus_tag="IRB70_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body L-ring protein FlgH"
                     /protein_id="HBC0630648.1"
                     /translation="MQKNAAHTYAISSLLVLSLTGCAWIPSTPLVQGATSAQPVPGPT
                     PVANGSIFQSAQPINYGYQPLFEDRRPRNIGDTLTIVLQENVSASKSSSANASRDGKS
                     NFGFDTVPRYLQGLFGNARADVEASGGNTFNGKGGANASNTFSGTLTVTVDQVLVNGN
                     LHVVGEKQIAINQGTEFIRFSGVVNPRTISGSNTVPSTQVADARIEYVGNGYINEAQN
                     MGWLQRFFLNLSPM"
     gene            complement(63808..64590)
                     /gene="flgG"
                     /locus_tag="IRB70_000700"
     CDS             complement(63808..64590)
                     /gene="flgG"
                     /locus_tag="IRB70_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgG"
                     /protein_id="HBC0630649.1"
                     /translation="MISSLWIAKTGLDAQQTNMDVIANNLANVSTNGFKRQRAVFEDL
                     LYQTIRQPGAQSSEQTTLPSGLQIGTGVRPVATERLHSQGNLSQTNNSKDVAIKGQGF
                     FQVMLPDGSSAYTRDGSFQVDQNGQLVTAGGFQVQPAITIPANALSITIGRDGVVSVT
                     QQGQAAPVQVGQLNLTTFMNDTGLESIGENLYTETQSSGAPNESTPGLNGAGLLYQGY
                     VETSNVNVAEELVNMIQVQRAYEINSKAVSTTDQMLQKLTQL"
     gene            complement(64727..65482)
                     /gene="flgF"
                     /locus_tag="IRB70_000701"
     CDS             complement(64727..65482)
                     /gene="flgF"
                     /locus_tag="IRB70_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal-body rod protein FlgF"
                     /protein_id="HBC0630650.1"
                     /translation="MDHAIYTAMGAASQTLNQQAVTASNLANASTPGFRAQLNALRAV
                     PVEGLSLPTRTLVTASTPGADMTPGKMDYTSRPLDVALQQDGWLAVQTDDGSEGYTRN
                     GSIQVDPTGQLTIQGHPVIGEAGPIAVPEGAEITIAADGTISALNPGDPANTVAPVGR
                     LKLVKATGSEVQRGDDGIFRLSAESQATRGPVLQADPTLRVMSGVLEGSNVNAVAAMS
                     DMIASARRFEMQMKVISSVDDNAGRANQLLSMS"
     gene            complement(65502..66707)
                     /gene="flgE"
                     /locus_tag="IRB70_000702"
     CDS             complement(65502..66707)
                     /gene="flgE"
                     /locus_tag="IRB70_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook protein FlgE"
                     /protein_id="HBC0630651.1"
                     /translation="MAFSQAVSGLNAAATNLDVIGNNIANSATYGFKSGTASFADMFA
                     GSKVGLGVKVAGITQDFTDGTTTNTGRGLDVAISQNGFFRLVDSNGSVFYSRNGQFKL
                     DENRNLVNMQGLQLTGYPATGTPPTIQQGANPTNISIPNTLMAAKTTTTASMQINLNS
                     SDPLPSVKAFDASNADSYNKKGSVTVFDSQGNAHDMSVYFVKTGDNNWDVYTLDSSDP
                     TGTANPATTLVFNANGVLTSGPTKDITTGAINGADPATFSLSFLNSMQQNTGANNIVA
                     TTQNGYKPGDLVSYQINDDGTVVGNYSNEQTQLLGQIVLANFANNEGLASEGDNVWSA
                     TQSSGVALLGTAGTGNFGTLTNGALEASNVDLSKELVNMIVAQRNYQSNAQTIKTQDQ
                     ILNTLVNLR"
     gene            complement(66732..67427)
                     /gene="flgD"
                     /locus_tag="IRB70_000703"
     CDS             complement(66732..67427)
                     /gene="flgD"
                     /locus_tag="IRB70_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook assembly protein FlgD"
                     /protein_id="HBC0630652.1"
                     /translation="MSIAVTTTDPTNTGVSTTSSSSLTGSNAADLQSSFLTLLVAQLK
                     NQDPTNPMENNELTSQLAQISTVSGIEKLNTMLGSISGQIDNSQSLQASNLIGHGVMI
                     PGTTVLAGTGSDEGAVTTTTPFGVELQQAADKVTATITDKNGAVVRTIDIGELTAGVH
                     SFTWDGTLTDGSTAPNGSYNVAISASSGGTQLVAQPLQFALVQGVIRGNNGNTLDLGT
                     YGTTTLDEVRQII"
     gene            complement(67439..67843)
                     /gene="flgC"
                     /locus_tag="IRB70_000704"
     CDS             complement(67439..67843)
                     /gene="flgC"
                     /locus_tag="IRB70_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgC"
                     /protein_id="HBC0630653.1"
                     /translation="MALLNIFDIAGSALTAQSQRLNVAASNLANADSLTGPDGQPYRA
                     KQVVFQVNAAPGAATGGVKVADVIESQAPDKLVYEPGNPLADAKGYVKMPNVDVVGEM
                     VNTMSASRSYQANVEVLNTVKSMMLKTLTLGQ"
     gene            complement(67847..68263)
                     /gene="flgB"
                     /locus_tag="IRB70_000705"
     CDS             complement(67847..68263)
                     /gene="flgB"
                     /locus_tag="IRB70_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body rod protein FlgB"
                     /protein_id="HBC0630654.1"
                     /translation="MLDKLDAALRFQQEALNLRAQRQEVLAANIANADTPGYQARDID
                     FASELKKVMQRGRDATSVVALTMTSTQHIPAQALTPPTAELQYRIPDQPSLDGNTVDM
                     DRERTQFADNSLQYQMSLSALSGQIKGMMNVLQSGN"
     gene            68418..69077
                     /gene="flgA"
                     /locus_tag="IRB70_000706"
     CDS             68418..69077
                     /gene="flgA"
                     /locus_tag="IRB70_000706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body P-ring formation protein
                     FlgA"
                     /protein_id="HBC0630655.1"
                     /translation="MLTIKRSVTIIAILFSPLSTASNLTSQLHTFFSAQLAGVSDEVR
                     VSIRTAPSLLPPCEQPLLSMSNNSRLWGNVNVLARCGNDKRYLQVNVQATGNYVVAAM
                     PIVRGGKLEAGNVKLKRGRLDTLPPRTVLDINQLVDAVSLRDLSPDQPIQLTQFRQAW
                     RVKAGQRVNVIASGDGFSANAEGQALNNAAVAQNARVRMVSGQVVSGVVDADGNILIN
                     L"
     gene            69153..69446
                     /gene="flgM"
                     /locus_tag="IRB70_000707"
     CDS             69153..69446
                     /gene="flgM"
                     /locus_tag="IRB70_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-sigma-28 factor FlgM"
                     /protein_id="HBC0630656.1"
                     /translation="MSIDRTSPLKPVSTVQPRETTDAPVTNTRAAKTTASTSTSVTLS
                     DAQAKLMQPGSSDINLERVEALKLAIRNGELKMDTGKIADALINEAQQDLQSN"
     gene            69451..69867
                     /gene="flgN"
                     /locus_tag="IRB70_000708"
     CDS             69451..69867
                     /gene="flgN"
                     /locus_tag="IRB70_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FlgN"
                     /protein_id="HBC0630657.1"
                     /translation="MTRLAEILDQMSAVLNDLKTVMDQEQQHLSMGQINGSQLQWITE
                     QKSSLLATLDYLEQLRRKEPNSANSVDISQRWQEITVKTQQLRQMNQHNGWLLEGQIE
                     RNQQALEMLKPHQEPTLYGANGQTSTTHRGSKKISI"
     gene            complement(69907..71442)
                     /gene="murJ"
                     /locus_tag="IRB70_000709"
     CDS             complement(69907..71442)
                     /gene="murJ"
                     /locus_tag="IRB70_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706990.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein biosynthesis integral membrane protein
                     MurJ"
                     /protein_id="HBC0630658.1"
                     /translation="MNLLKSLAAVSSMTMFSRVLGFARDAIVARIFGAGMATDAFFVA
                     FKLPNLLRRIFAEGAFSQAFVPILAEYKSKQGEDATRVFVSYVSGLLTLALAVVTVAG
                     MLAAPWVIMVTAPGFADTADKFALTSQLLKITFPYILLISLASLVGAILNTWNRFSIP
                     AFAPTLLNISMIGFALFAAPYFNPPVLALAWAVTVGGILQLVYQLPHLKKIGMLVLPR
                     INFHDAGAMRVVKQMGPAILGVSVSQISLIINTIFASFLASGSVSWMYYADRLMEFPS
                     GVLGVALGTILLPSLSKSFASGNHDEYNRLMDWGLRLCFLLALPSAVALGILSGPLTV
                     SLFQYGKFTAFDALMTQRALIAYSVGLIGLIVVKVLAPGFYSRQDIKTPVKIAIVTLI
                     LTQLMNLAFIGPLKHAGLSLSIGLAACLNASLLYWQLRKQKIFTPQPGWMAFLLRLVV
                     AVLVMSGVLLGMLHIMPEWSLGTMPWRLLRLMAVVLAGIAAYFAALAVLGFKVKEFAR
                     RTV"
     gene            complement(71552..72475)
                     /locus_tag="IRB70_000710"
     CDS             complement(71552..72475)
                     /locus_tag="IRB70_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBC0630659.1"
                     /translation="MKKLRIGVVGLGGIAQKAWLPVLAAASDWTLQGAWSPTRAKALP
                     ICDSWRIPYADSLSSLAASCDAVFVHSSTASHFDVVSTLLNAGVHVCVDKPLAENLRD
                     AERLVELAARKKLTLMVGFNRRFAPLYGELKTQLATAASLRMDKHRSNSVGPHDLYFT
                     LLDDYLHVVDTALWLSGGKASLDGGTLLTNDAGEMLFAEHHFSAGPLQITTCMHRRAG
                     SQRETVQAVTDGALIDITDMREWREERGQGVVHKPIPGWQSTLEQRGFVGCARHFIEC
                     VQNQTVPQTAGEQAVLAQRIVDKIWRDAMSE"
     gene            complement(72477..73124)
                     /locus_tag="IRB70_000711"
     CDS             complement(72477..73124)
                     /locus_tag="IRB70_000711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceH family protein"
                     /protein_id="HBC0630660.1"
                     /translation="MKYQLTALEARVIGCLLEKQVTTPEQYPLSVNGVVTACNQKTNR
                     EPVMNLSESEVQEQLDNLVKRHYLRTVSGFGNRVTKYEQRFCNSEFGDLKLSAAEVAL
                     ITTLLLRGAQTPGELRSRAARMYEFSDMAEVKSTLEQLANREDGPFVVRLAREPGKRE
                     SRYMHLFSGEVEDQPAVMDMSNAVDGDLQARVEALEIEVAELKQRLDSLLAHLGD"
     gene            complement(73135..73719)
                     /gene="rimJ"
                     /locus_tag="IRB70_000712"
     CDS             complement(73135..73719)
                     /gene="rimJ"
                     /locus_tag="IRB70_000712"
                     /EC_number="2.3.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S5-alanine
                     N-acetyltransferase"
                     /protein_id="HBC0630661.1"
                     /translation="MFGYRSNVPKVRLTTDRLVVRLVHDRDAWRLADYYAENRHFLKP
                     WEPVRDESHCYPSGWQARLGMINEFHKQGSAFYFGLFDPDEKEIIGVANFSNVVRGSF
                     HACYLGYSIGQKWQGKGLMFEALTAAIRYMQRTQHIHRIMANYMPHNKRSGDLLARLG
                     FEKEGYAKDYLLIDGQWRDHVLTALTTPDWTPGR"
     gene            73955..75163
                     /gene="mdtH"
                     /locus_tag="IRB70_000713"
     CDS             73955..75163
                     /gene="mdtH"
                     /locus_tag="IRB70_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415583.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtH"
                     /protein_id="HBC0630662.1"
                     /translation="MSRVSQARNLGKYFLLIDNMLVVLGFFVVFPLISIRFVDQMGWA
                     AVMVGIALGLRQFIQQGLGIFGGAIADRFGAKPMIVTGMLMRAAGFATMGIAHEPWLL
                     WFSCLLSGLGGTLFDPPRSALVVKLIRPQQRGRFFSLLMMQDSAGAVIGALLGSWLLQ
                     YDFRLVCATGAVLFVLCAAFNAWLLPAWKLSTVRTPVREGMTRVMRDKRFVTYVLTLA
                     GYYMLAVQVMLMLPIMVNDVAGAPSAVKWMYAIEACLSLTLLYPIARWSEKHFRLEHR
                     LMAGLLIMSLSMMPVGMVSGLQQLFTLICLFYIGSIIAEPARETLSASLADARARGSY
                     MGFSRLGLAIGGAIGYIGGGWLFDLGKSAHQPELPWMMLGIIGIFTFLAVGWQFSQKR
                     TARRLLERDA"
     gene            75227..75874
                     /gene="grxB"
                     /locus_tag="IRB70_000714"
     CDS             75227..75874
                     /gene="grxB"
                     /locus_tag="IRB70_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 2"
                     /protein_id="HBC0630663.1"
                     /translation="MKLFIYDHCPYCLKARMIFGLKNIPVELHVLLNDDAETPTRMVG
                     QKQVPILQKDDSRYMPESMDIVHYVDKLDGKPLLTGKRSPAIEEWLRKVNGYANKLLL
                     PRFAKSAFDEFSTPAARKYFVDKKEASAGNFADLLAHSDGLIKNISDDLRALDKLIVK
                     PNAVNGELSEDDIQLFPLLRNLTLVAGINWPSRVADYRDNMAKQTQINLLSSMAI"
     gene            76008..76568
                     /locus_tag="IRB70_000715"
     CDS             76008..76568
                     /locus_tag="IRB70_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBC0630664.1"
                     /translation="MNKFLFAAALIVSGLLVGCNQLTQYTITEQEINQSLAKHNNFSK
                     DIGLPGVADAHIVLTNLTSQIGREEPNKVTLTGDANLDMNSLFGSQKATMKLKLKALP
                     VFDKEKGAIFLKEMEVVDATVQPEKMQTVMQTLLPYLNQALRNYFNQQPAYVLREDGS
                     QGEAMAKKLAKGIEVKPGEIVIPFTD"
     gene            76674..77720
                     /gene="pyrC"
                     /locus_tag="IRB70_000716"
     CDS             76674..77720
                     /gene="pyrC"
                     /locus_tag="IRB70_000716"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBC0630665.1"
                     /translation="MTAPSQVLKIRRPDDWHLHLRDGDMLKTVVPYTSEIYGRAIVMP
                     NLAPPVTTVEAAVAYRQRILDAVPAGHDFTPLMTCYLTDSLDPNELERGFNEGVFTAA
                     KLYPANATTNSSHGVTSVDAIMPVLERMEKIGMPLLVHGEVTHADIDIFDREARFIES
                     VMEPLRQRLTALKVVFEHITTKDAADYVRDGNERLAATITPQHLMFNRNHMLVGGVRP
                     HLYCLPILKRNIHQQALRELVASGFNRVFLGTDSAPHARHRKESSCGCAGCFNAPTAL
                     GSYATVFEEMNALQHFEAFCSVNGPQFYGLPVNDTFIELVREEQQVAESIALTDDTLV
                     PFLAGETVRWSVKQ"
     gene            77794..78039
                     /gene="dinI"
                     /locus_tag="IRB70_000717"
     CDS             77794..78039
                     /gene="dinI"
                     /locus_tag="IRB70_000717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein I"
                     /protein_id="HBC0630666.1"
                     /translation="MRIEVTIAKTSPLPAGAIDALAGELSRRIQYAFPDNEGHVSVRY
                     AAANNLSVIGATKEDKQRISEILQETWESADDWFVSE"
     gene            78329..78583
                     /gene="bssS"
                     /locus_tag="IRB70_000718"
     CDS             78329..78583
                     /gene="bssS"
                     /locus_tag="IRB70_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415578.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator BssS"
                     /protein_id="HBC0630667.1"
                     /translation="MEKNNEVIQTHPLVGWDISTVDSYDALMLRLHYQTPNKSEQEGT
                     EVGQTLWLTTDVARQFISILEAGIAKIESGDFQVNEYRRH"
     gene            78698..79816
                     /gene="solA"
                     /locus_tag="IRB70_000719"
     CDS             78698..79816
                     /gene="solA"
                     /locus_tag="IRB70_000719"
                     /EC_number="1.5.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-methyl-L-tryptophan oxidase"
                     /protein_id="HBC0630668.1"
                     /translation="MKYDLIIIGSGSIGAAAGYYATRAGLNVLMTDAHMPPHQHGSHH
                     GDTRLIRHAYGEGEKYVPLVLRAQMLWDELSRHNEDDPIFVRSGVINLGPADSAFLAN
                     VAHSAEQWQLNVEKLDAQGIMARWPEIRVPDNYIGLFETDSGFLRSELAIKTWIQLAK
                     EAGCAQLFNCPVTAIRHDDDGVTIETADGEYRAKKAIVCAGTWVKDLLPELPVQPVRK
                     VFAWYQADGRYSVKNKFPAFTGELPNGDQYYGFPAENDALKIGKHNGGQVIHSADERV
                     PFAEVVSDGSEAFPFLRNVLPGIGCCLYGAACTYDNSPDEDFIIDTLPGHDNTLLITG
                     LSGHGFKFASVLGEIAADFAQDKKSDFDLTPFRLSRFQ"
     gene            79864..79977
                     /locus_tag="IRB70_000720"
     CDS             79864..79977
                     /locus_tag="IRB70_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706980.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceO family protein"
                     /protein_id="HBC0630669.1"
                     /translation="MRRLLHYLINNIRKHLMLYLFLWGLLAIMDLIYVFYF"
     gene            80238..80804
                     /locus_tag="IRB70_000721"
     CDS             80238..80804
                     /locus_tag="IRB70_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HBC0630670.1"
                     /translation="MSFTNTPERYGVISAAFHWLSAIIVYGMFALGLWMVTLSYYDGW
                     YHKAPELHKSIGILLMMGLVIRVLWRVISPPPGPLPSYSPITRLAAKAGHLALYLLLF
                     AIGISGYLISTADGKPISVFGWFDVPATLADAGAQADFAGALHFWLAWSVVVLSVMHG
                     FMALKHHFIDKDDTLKRMLGKSSSDYGV"
     gene            80808..81383
                     /locus_tag="IRB70_000722"
     CDS             80808..81383
                     /locus_tag="IRB70_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceI family protein"
                     /protein_id="HBC0630671.1"
                     /translation="MKKSLLGLTFASLMFSAGSAVAADYKIDKEGQHAFVNFRIQHLG
                     YSWLYGTFKDFDGTFTFDEKNPAADKVNVTINTTSVDTNHAERDKHLRSADFLNTAKY
                     PQATFTSTSVKKDGDELDITGDLTLNGVTKPVTLEAKLIGQGDDPWGGKRAGFEAEGK
                     IKLKDFNIKTDLGPASQEVDLIISVEGVQQK"
     gene            complement(81425..82477)
                     /locus_tag="IRB70_000723"
     CDS             complement(81425..82477)
                     /locus_tag="IRB70_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706977.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBC0630672.1"
                     /translation="MPVLHNRISNDALKAKMLAESEPRTTISFYKYFHIADPKATRDA
                     LYQLFTALNVFGRVYLAHEGINAQISVPESNVETFRAQLYAFDPALEGLRLNIALDDD
                     GKSFWVLRMKVRDRIVADGIDDPHFDASNVGEYLQAAEVNAMLDDPDALFIDMRNHYE
                     YEVGHFENALEIPADTFREQLPKAVEMMQAHKDKKIVMYCTGGIRCEKASAWMKHNGF
                     NKVWHIEGGIIEYARKAREQGLPVRFIGKNFVFDERMGERISDEIIAHCHQCGAPCDS
                     HTNCKNDGCHLLFIQCPVCAEKYKGCCSEICCEESALPPEEQRRRRAGRENGNKIFNK
                     SRGRLNTTLGIPDPTE"
     gene            82702..83622
                     /gene="lpxL"
                     /locus_tag="IRB70_000724"
     CDS             82702..83622
                     /gene="lpxL"
                     /locus_tag="IRB70_000724"
                     /EC_number="2.3.1.241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) lauroyltransferase"
                     /protein_id="HBC0630673.1"
                     /translation="MTNLPKFSTALLHPRYWLTWLGIGVLWLVVQLPYPVIYRLGCGL
                     GKLALRFMKRRAKIVHRNLELCFPEMSEQERRKMVVKNFESVGMGLMETGMAWFWPDR
                     RIARWTEVIGMEHIRDVQAQKRGILLVGIHFLTLELGARQFGMQEPGIGVYRPNDNPL
                     IDWLQTWGRLRSNKSMLDRKDLKGMIKALKKGEVVWYAPDHDYGPRSSVFVPLFAVEQ
                     AATTTGTWMLSRMSGACLVPFVPRRKPDGKGYQLIILPPECSPPLDDAETTAAWMNKV
                     VEKCIMMAPEQYMWLHRRFKTRPEGVPSRY"
     gene            83794..85020
                     /gene="mdtG"
                     /locus_tag="IRB70_000725"
     CDS             83794..85020
                     /gene="mdtG"
                     /locus_tag="IRB70_000725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtG"
                     /protein_id="HBC0630674.1"
                     /translation="MSPCENDTPINWKRNLIVAWLGCFLTGAAFSLVMPFLPLYVEQL
                     GVTGHSALNMWSGIVFSITFLFSAIASPFWGGLADRKGRKLMLLRSALGMGIVMVLMG
                     LAQNIWQFLILRALLGLLGGFVPNANALIATQVPRNKSGWALGTLSTGGVSGALLGPM
                     AGGLLADSYGLRPVFFITASVLILCFFVTLFCIREKFQPVSKKEMLHMREVVTSLKNP
                     KLVLSLFVTTLIIQVATGSIAPILTLYVRELAGNVSNVAFISGMIASVPGVAALLSAP
                     RLGKLGDRIGPEKILITALIFSVLLLIPMSYVQTPLQLGILRFLLGAADGALLPAVQT
                     LLVYNSSNQIAGRIFSYNQSFRDIGNVTGPLMGAAISANYGFRAVFLVTAGVVLFNAV
                     YSWNSLRRRRIPQVSN"
     gene            85103..85477
                     /locus_tag="IRB70_000726"
     CDS             85103..85477
                     /locus_tag="IRB70_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309456.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HBC0630675.1"
                     /translation="MTMYATLEEAIDAAREEFLADNPGIDAEDANVQQFNAQKYVLQD
                     GDIMWQVEFFADEGEEGECLPMLSGEAAQSVFDGDYDEIEIRQEWQEENTLHEWDEGE
                     FQLEPPLDTEEGRAAADEWDER"
     gene            complement(85478..85705)
                     /locus_tag="IRB70_000727"
     CDS             complement(85478..85705)
                     /locus_tag="IRB70_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HBC0630676.1"
                     /translation="MRLIVVSIMVTLLSGCGSIISRTIPGQGHGNQYYPGVQWDVRDS
                     AWRYVTILDLPFSLVFDTLLLPIDIHHGPYE"
     gene            complement(85878..88421)
                     /gene="mdoH"
                     /locus_tag="IRB70_000728"
     CDS             complement(85878..88421)
                     /gene="mdoH"
                     /locus_tag="IRB70_000728"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis glucosyltransferase MdoH"
                     /protein_id="HBC0630677.1"
                     /translation="MNKTTEYIDAMPIAASEKAALPKTDIRAVHQALDAEHRTWARED
                     DSPQGSVKARLEQAWPDSLADGQLIKDDEGRDQLKAMPEAKRSSMFPDPWRTNPVGRF
                     WDRLRGRDVTPRYLARLTKEEQESEQKWRTVGTIRRYILLILTLAQTVVATWYMKTIL
                     PYQGWALINPMDMVGQDVWVSFMQLLPYMLQTGILILFAVLFCWVSAGFWTALMGFLQ
                     LLIGRDKYSISASTVGDEPLNPEHRTALIMPICNEDVNRVFAGLRATWESVKATGNAK
                     HFDVYILSDSYNPDICVAEQKAWMELIAEVGGEGQIFYRRRRRRVKRKSGNIDDFCRR
                     WGSQYSYMVVLDADSVMTGDCLCGLVRLMEANPNAGIIQSSPKASGMDTLYARCQQFA
                     TRVYGPLFTAGLHFWQLGESHYWGHNAIIRVKPFIEHCALAPLPGEGSFAGSILSHDF
                     VEAALMRRAGWGVWIAYDLPGSYEELPPNLLDELKRDRRWCHGNLMNFRLFLVKGMHP
                     VHRAVFLTGVMSYLSAPLWFMFLALSTALQVVHALTEPQYFLQPRQLFPVWPQWRPEL
                     AIALFASTMVLLFLPKLLSILLIWCKGTKEYGGFWRVTLSLLLEVLFSVLLAPVRMLF
                     HTVFVVSAFLGWEVVWNSPQRDDDSTSWGEAFKRHGSQLLLGLVWAVGMAWLDLRFLF
                     WLAPIVFSLILSPFVSVISSRATVGLRTKRWKLFLIPEEYSPPQVLVDTDRFLEMNRQ
                     RSLDDGFMHAVFNPSFNALATAMATARHRASKVLEIARDRHVEQALNETPEKLNRDRR
                     LVLLSDPVTMARLHFRVWNSPERYSSWVSYYEGIKLNPLALRKPDAASQ"
     gene            complement(88414..89949)
                     /gene="mdoG"
                     /locus_tag="IRB70_000729"
     CDS             complement(88414..89949)
                     /gene="mdoG"
                     /locus_tag="IRB70_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoG"
                     /protein_id="HBC0630678.1"
                     /translation="MMKMRWLSAAVMLTLYTSSSWAFSIDDVAKQAQSLAGKGYEAPK
                     SNLPSVFRDMKYADYQQIQFNHDKAYWNNLKTPFKLEFYHQGMYFDTPVKINEVTATA
                     VKRIKYSPDYFTFGDVQHDKDTVKDLGFAGFKVLYPINSKDKNDEIVSMLGASYFRVI
                     GAGQVYGLSARGLAIDTALPSGEEFPRFKEFWIERPKPTDKRLTIYALLDSPRATGAY
                     KFVVMPGRDTVVDVQSKIYLRDKVGKLGVAPLTSMFLFGPNQPSPANNYRPELHDSNG
                     LSIHAGNGEWIWRPLNNPKHLAVSSFSMENPQGFGLLQRGRDFSRFEDLDDRYDLRPS
                     AWVTPKGEWGKGSIELVEIPTNDETNDNIVAYWTPDQLPEPGKEMNFKYTITFSRDED
                     KLHAPDNAWVQQTRRSTGDVKQSNLIRQPDGTIAFVVDFTGAEMKKLPEDTPVTAQTS
                     IGDNGEIVESTVRYNPVTKGWRLVMRVKVKDAKKTTEMRAALVNADQTLSETWSYQLP
                     ANE"
     gene            90343..91500
                     /gene="mdoC"
                     /locus_tag="IRB70_000730"
     CDS             90343..91500
                     /gene="mdoC"
                     /locus_tag="IRB70_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706958.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucans biosynthesis protein MdoC"
                     /protein_id="HBC0630679.1"
                     /translation="MNPVPAQREYFLDSIRAWLMLLGIPFHISLIYSSHTWHVNSAEP
                     SLWLTLFNDFIHSFRMQVFFVISGYFSYMLFLRYPLKKWWKVRVERVGIPMLTAIPLL
                     TLPQFIMLQYVKGKAESWPGLSMYDKYNTLAWELISHLWFLLVLVVMTTLCVWIFKRI
                     RNNLENSDKTNKKFSMVKLSVIFLCLGIGYAVIRRTIFIVYPPILSNGMFNFIVMQTL
                     FYLPFFILGALAFIFPHLKALFTTPSRGCTLAAALAFVAYLLNQRYGSGDAWMYETES
                     VITMVLGLWMVNVVFSFGHRLLNFQSARVTYFVNASLFIYLVHHPLTLFFGAYITPHI
                     TSNWLGFLCGLIFVVGIAIILYEIHLRIPLLKFLFSGKPVVKRENDKAPAR"
     gene            complement(91508..92989)
                     /gene="clsC"
                     /locus_tag="IRB70_000731"
     CDS             complement(91508..92989)
                     /gene="clsC"
                     /locus_tag="IRB70_000731"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706957.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase ClsC"
                     /protein_id="HBC0630680.1"
                     /translation="MMKKTPTSTKDSLPNKEMNDLPRLASAVLPLCSQHPGQCGLFPL
                     EKSLDAFAARYRLAEMAEHTLDVQYYIWQDDMSGRLLFSALLAAAKRGVRVRLLLDDN
                     NTPGLDDILRLLDSHPRIEVRLFNPFSFRLLRPLGYITDFSRLNRRMHNKSFTVDGVV
                     TLVGGRNIGDAYFGAGEEPLFSDLDVMAIGPVVEDVADDFARYWYCKSVSPLQQVLDV
                     PEGEMADRIELPASWHNDAMTHRYLRKMESSPFINHLVDGTLPLIWAKTRLLSDDPAK
                     GEGKAKRHSLLPQRLFDIMGSPSERIDIISAYFVPTRAGVAQLLRMVRKGVKIAILTN
                     SLAANDVAVVHAGYARWRKKLLRYGVELYELKPTREQSSTLHDRGITGNSGASLHAKT
                     FSIDGKTVFIGSFNFDPRSTLLNTEMGFVIESETLAQLIDKRFIQSQYDAAWQLRLDR
                     WGRINWVDRHAKKEIILKKEPATSFWKRVMVRLASILPVEWLL"
     gene            complement(92931..93464)
                     /gene="ymdB"
                     /locus_tag="IRB70_000732"
     CDS             complement(92931..93464)
                     /gene="ymdB"
                     /locus_tag="IRB70_000732"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyl-ADP-ribose deacetylase"
                     /protein_id="HBC0630681.1"
                     /translation="MKTRIHVVQGDITKLAVDVIVNAANPSLMGGGGVDGAIHRAAGP
                     ALLDACLKVRQQQGDCPTGHAVITLAGDLPAKAVVHTVGPVWRGGEQNEDQLLQDAYL
                     NSLRLVAANSYTSVAFPAISTGVYGYPRAAAAEIAVKTVSEFITRHALPEQVYFVCYD
                     EENAYLYERLLTQQGDE"
     gene            complement(93559..93870)
                     /locus_tag="IRB70_000733"
     CDS             complement(93559..93870)
                     /locus_tag="IRB70_000733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBC0630682.1"
                     /translation="MFRPFLDSLMLGSMFFPFIAIAGSSAQGGVIHFYGQIVEPACDV
                     STQSSPVEMNCPQNGSVPGRTYSSKALMSGNVKNAQIASVKVQYLDKQKKLAVMNIEY
                     N"
     gene            complement(93991..94323)
                     /gene="csgC"
                     /locus_tag="IRB70_000734"
     CDS             complement(93991..94323)
                     /gene="csgC"
                     /locus_tag="IRB70_000734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli assembly protein CsgC"
                     /protein_id="HBC0630683.1"
                     /translation="MNALLLLAALSSQITFNTTQQGDMYTIIPEVTLTQSCLCRVQIL
                     SLREGSSGQSQTKQEKTLSLPANQPIALTKLSLNISPDDRVKIVVTVSDGQSLHLSQQ
                     WPPSSEKS"
     gene            complement(94382..94837)
                     /gene="csgA"
                     /locus_tag="IRB70_000735"
     CDS             complement(94382..94837)
                     /gene="csgA"
                     /locus_tag="IRB70_000735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin major subunit CsgA"
                     /protein_id="HBC0630684.1"
                     /translation="MKLLKVAAIAAIVFSGSALAGVVPQYGGGGNHGGGGNNSGPNSE
                     LNIYQYGGGNSALALQADARNSDLTITQHGGGNGADVGQGSDDSSIDLTQRGFGNSAT
                     LDQWNGKDSTMTVKQFGGGNGAAVDQTASNSSVNVTQVGFGNNATAHQY"
     gene            complement(94878..95333)
                     /gene="csgB"
                     /locus_tag="IRB70_000736"
     CDS             complement(94878..95333)
                     /gene="csgB"
                     /locus_tag="IRB70_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curlin minor subunit CsgB"
                     /protein_id="HBC0630685.1"
                     /translation="MKNKLLFMMLTILGAPGIAAAAGYDLANSEYNFAVNELSKSSFN
                     QAAIIGQAGTNNSAQLRQGGSKLLAVVAQEGSSNRAKIDQTGDYNLAYIDQAGNANDA
                     SISQGAYGNTAMIIQKGSGNKANITQYGTQKTAIVVQRQSQMAIRVTQR"
BASE COUNT        23455 a        25044 c        23549 g        23385 t
ORIGIN      
        1 atgttttcac taaatctcat tttgtttaat ctctattgag attccttgct ttaaattttg
       61 ttttatatag ataatgacat taatttttaa ttaatttatt tttttgggag taatatacac
      121 atatgcaaaa tcaagaaatg aacatccaaa tgaactatat taagcaccgt gggataagac
      181 ataacaaatg aagtggatag taattgacac ggtaattcaa cctacatgcg gcatatcttt
      241 ttcagccata tggggtgata tgaaaatgat catctggtat caatccacta tatttcttcc
      301 tcctggcagg atatttacac cggttaaatc tggtattatc cttaaggata aagaatatcc
      361 tattactatt tataacatcg caccattcaa caaggattta tggagtttac tcaaaagcag
      421 tcaagagtgt cctccaggag aaagcaaaat aacaaataaa tgtttgcata atagttgcat
      481 tataaaaata tgcccatatg ggctcaagta atgggcttca tataaatatg ctcaatgtgc
      541 tattaataat acccacataa ataaaacaac gggcgtgtta tacgcccgtt acaatattta
      601 acacatgtag taattacata ttcttgatga tcgcgtcacc aaactctgaa catttcagca
      661 gtttagcgcc ttccatcaga cgttcgaagt cataggttac agtcttggcg ttgattgcgc
      721 cttccatacc tttaacaatc aagtctgcgg cttcagtcca gcccatatgg cgtaacatca
      781 tctcagcgga gagaataata gagcctgggt ttactttgtc ctgaccggca tatttcggcg
      841 cagtaccgtg ggtggcttca aacagggcgc attcgtcacc gatgtttgcg ccaggggcga
      901 taccgatacc gccaacctgc gctgccaggg cgtcagaaat gtagtcaccg ttcaggttca
      961 tacaggcgat aacatcatat tcagccggac gcagcaggat ctgttgcagg aatgcatcag
     1021 caatcacgtc tttaatgacg atctctttgc cggtgttcgg gtttttaact ttcagccacg
     1081 ggccgccgtc gatcagttca ccgccaaact cttcacgcgc cagctggtag ccccagtctt
     1141 taaacgcgcc ttcggtgaac ttcatgatgt tgcctttgtg caccagggtc acagagtcac
     1201 gatcgttagc aattgcgtat tcgatcgctg cacgaaccag acgtttggtg ccttcttcag
     1261 aacacggctt aataccgatg ccgcaatgtt ccgggaagcg aattttcttc acgcccatct
     1321 cttcacgcag gaatttaatc actttctcag cgtcggcaga gtctgctttc cattcgatac
     1381 ccgcataaat gtcttccgag ttttcacgga agataaccat atcggtcagt tcagggtgtt
     1441 taaccgggct tggagtgccc tgatagtaac gtaccggacg caggcagatg tagagatcca
     1501 gttcctggcg cagagcaacg ttgagagagc gaataccacc accaaccgga gtggtcagcg
     1561 ggcctttgat ggcaacgcga tattcacgaa tcagatcaag ggtttcagca ggtagccaga
     1621 catcctgacc ataaacctgt gtggattttt caccggtgta aatttccatc caggagattt
     1681 tacgctcgcc tttataggct ttctcgactg cagcgtcgac cactttcagc atggctgggg
     1741 ttacatctac accgattcca tcaccttcaa tgtaagggat aatcggattt tcaggaacgt
     1801 tgagtttgcc gttttgcagg gtgatcttct tgccttgtgc cggaacaact actttacttt
     1861 ccattcacct ctccttcgag cgctactggt ttgctcgtct gccaccacgt tgcatatgcg
     1921 tttgcgtcct gcgatacgga tgctttagag caatttttta ttaatgattt gtaattggct
     1981 tgtcaatact accctattgt ttgccgtcat gaaagatgcg cgttattagg ctataatgcg
     2041 gcaattcata atctctgaaa ataccatgca aaaaacttct tttagaccaa agacagtatt
     2101 tttctgacct tcaaataagg tattaaatat caataattta catcagattt taagcaataa
     2161 aaaaaacacc agagataact aacaaggtgc tatttggtca aaatttgaca ttactcgact
     2221 cagcgactat ctcactttga gcactattgg gaaaattatc aaaagtcatg gttgaagcga
     2281 caagcaacga gtaaattatg gcatccccct ttttgaggtt cacatgaaac gctttgcact
     2341 gatagctgtg aaactcgttg cctttactgg ttctgcatct gctgcaaccg aagaaatcaa
     2401 cttcaagtaa cagaaacact atataacaat ggagtgttga caaatggata ctaccgaaga
     2461 acgcaatgga acatatttct acagaggaca cccgaacctg tccaaaatag aactactcaa
     2521 cgtcatattc cttgaagaat tctgtaagga attggggatt gattcggtat caggtgcagc
     2581 aatcttatct ggtcaaccgt ggctgggtac aagagcgaag ccgcaagggg caaccctggg
     2641 aacaagtgtt gtctcaaagt atgcgcgtat actgatgaga gatgcacgca tgccttttgg
     2701 tatttctgtt catacaccag tgggtgtaag gatgcagaaa tctaataagc ttgctgcaat
     2761 tatcgctcgt tgggtcccgt ggattggttg ggcttcactg tcgatgagtc tttacagggt
     2821 ttcgactcgt acccaggaaa aatacaatct gattgccaaa cctcaagacc gtattaagtg
     2881 gacttccttc taatggcgac aacaatcaca gacgaagttt tagcactgtt ccgtgatgag
     2941 attccaggtt atcaggatga ccacgggaag gaaattccgt tagaactgga ctctgatttg
     3001 ttcgactatc cacgagatga tttagaggac gctatacgga aatacaaaga gaggtttggg
     3061 attaacctgg ataatctgga ctggtctttg taccttccat gggagtctgc accattgctt
     3121 caacgatggt tcaagctcaa gcgggaagag gtagaaacaa cacgtttacc gttaactgta
     3181 cggatgtttg cagaatcagc agaagcggga aaatggctgt atcagtagaa taaaaaagaa
     3241 ggctgcgatg cccctcttat tactgctgat gatggtagtg gtaaagcatc atcctaaact
     3301 tgaacagtga agtgctgtca cccatcagta atacagaaac actatttttc ataccagtat
     3361 ttattcaatt catcaatgta aaatgtgttc attgggccat atttatcacc atgcagccac
     3421 acaaccgctg ctcactaacc caggtattga tgaaaccgcg ctgaagagcc tgaaccctga
     3481 acctctaacg agtaccttaa aagtccaatg caatccgaca ctgtgctacc ctctgcgtat
     3541 agctctattt ggaatttacc atgaaatact ttagcgattc taaatcttct tttagaaaaa
     3601 aacaggttag tcgactaaac tcgcaacact ccactaagcg taaacctgaa aaccagccca
     3661 cgcgtgtgat cctgttcaat aaaccctacg atgttcttcc gcagttcacc gatgaagccg
     3721 gacgcaaaac attaaaagaa ttcatcccgg ttcagggcgt ttatgcagca ggtcgtcttg
     3781 accgcgatag cgaagggtta ctggtgctga ccaataacgg cgcgttgcag gcgcgtttaa
     3841 cccagccggg taaacgcacc ggaaaaatct attatgtgca ggtggaaggt attcccacac
     3901 aagacgcact tgaagccttg cgcaatggcg taaccttaaa tgatggccct accctgcccg
     3961 caggcgtaga gctggttgac gaacccgcgt ggttatggcc gcggaatcca ccaattcgtg
     4021 aacgcaaaag tattcccacc agctggctga agatcacctt atatgaagga cgtaatcgcc
     4081 aggtgcgccg catgaccgcc catgttggtt tccccacgct gcgactgatt cgctatgcga
     4141 tgggtgatta ctctttggat aatcttgcca atggcgaatg gcgagacgcg acagattaag
     4201 gatgcaaaat gtttaaaccg cacgttaccg ttgcctgcgt ggtgcacgca gaaggcaaat
     4261 ttttagtcgt tgaagagacg attaatggta aagcgttatg gaaccaacct gccgggcatc
     4321 tggaagccga tgaaacctta gtggaagccg ccgcccgtga gctgtgggaa gaaaccggca
     4381 tcagcgcgca gccgcaacac tttattcgta tgcatcagtg gattgcgcca gataaaacgc
     4441 cgtttttgcg tttcctcttt gccattgagc ttgagcaaat atgcccgacc cagcctcatg
     4501 acagcgatat cgactgctgc cgttgggtta gcgccgaaga aattttacag gcgtcaaatc
     4561 tgcgttcgcc gctggtggcg gaaagtattc gttgttatca aagcgggcaa cgctatccgc
     4621 tggagatgat tggcgatttt aactggcctt ttacaaaggg tgtcatctaa aaggctgcgt
     4681 gatagaatac gccgccttga agttcaatgt cgtgagtgat ccaatgtctg aaaccgcaaa
     4741 aaaagtaatc gtcggcatgt ccggcggtgt cgattcctcc gtttctgcct ggctgttgca
     4801 acaacaggga tatcaggtcg aaggcctgtt tatgaagaac tgggaagaag acgacggtga
     4861 ggaatattgc acagcggcag cggatctggc tgatgcccag gctgtctgcg acaagctcgg
     4921 cattgaactg cacaccgtta actttgctgc cgagtactgg gacaacgtct tcgaactgtt
     4981 ccttgccgaa tataaagccg gtcgcacgcc aaatccggat attctgtgca acaaagagat
     5041 caaatttaaa gctttcctcg aatttgccgc cgaagattta ggtgccgatt atatcgctac
     5101 cggtcattac gtacgtcggg cagatgtcga tggcaagagc cgcctgctgc gtggtctgga
     5161 cagcaataaa gaccagagct acttccttta tacgctcagc catgagcaaa ttgcgcaaag
     5221 cctgttcccg gtcggcgaac tggaaaaacc gcaggtgcgt aagattgctg aagatctcgg
     5281 tctggtcacc gcgaagaaaa aagattctac cggtatctgc tttatcggcg agcgtaaatt
     5341 ccgcgagttc ctgggccgtt atctcccggc gcaaccgggc aaaatcatta ccgtcgatgg
     5401 cgatgaaatt ggtgagcacc aggggctgat gtatcacacc ctcggtcagc gtaaaggtct
     5461 gggtatcggt ggcaccaaag acggcaccga agaaccgtgg tatgtggtcg ataaagacgt
     5521 cgaaaacaac attctgattg ttgcgcaagg ccatgaacac ccgcgtctga tgtctgtcgg
     5581 tctgattgcc cagcagctgc actgggtcga tcgcgagccg ttcaccggta ctatgcgttg
     5641 cacagtaaaa acccgctatc gccagaccga catcccgtgc accgtcaagg cgctggacga
     5701 tgatcgcatt gaagtgattt tcgatgagcc ggttgccgcc gtgacgccgg gccagtctgc
     5761 cgttttctat aacggtgaag tgtgcctcgg tggcggtatt attgagcagc gtctgccgct
     5821 gccggtctga ttattatctt tacttaaaac aaggaagcag tgaacgtggc aaagaattac
     5881 tatgacatca ccctcgccct ggccggtatt tgtcagtcgg cacgcctggt gcaacaactc
     5941 gctcaccagg ggcattgtga tggcgatgcg ctacacgtct cactcaacag tattatcgat
     6001 atgaacccca gctcaacgct ggcggttttt ggcggcagcg aagccaacct gcgcgtcggg
     6061 ctggaaaccc tgctcggcgt gctcaatgcc agcagtcgcc agggcttaaa cgctgaatta
     6121 acccgctaca cactcagcct gatggtgctt gagcgcaaac tctcctcagc gaaaggtgcg
     6181 ctcgacactc tgggcaaccg gatcaacggc ctgcaacgcc agctcgaaca cttcgattta
     6241 cagtccgaaa cgctgatgag cgcgatggct gctatctatg ttgatgtgat tagcccgctt
     6301 ggcccgcgca ttcaggtaac cggttcccct gctgtactgc aaagcccaca agtgcaggcg
     6361 aaagttcgcg caaccctgct ggcaggcatt cgcgccgccg tgctctggca ccaggttggc
     6421 ggcggacgtc tgcaactgat gttttctcgt aatcgcctga ccactcaggc aaaacaaatt
     6481 cttgctcatt taaccccgga gttgtgatct atggaattat cctcactgac cgccgtttcc
     6541 cctgtcgatg gacgctacgg cgataaagtc agcgcgctgc gcgggatttt cagcgaatat
     6601 ggtttgctga aattccgtgt acaagttgaa gtacgttggc tgcaaaaact ggccgcgcac
     6661 gcagcgatca aggaagttcc tgcttttgct gccgacgcaa tcggttacct tgatgcaatt
     6721 gtcgccagtt tcagcgaaga agatgccgca cgcatcaaaa ccatcgagcg taccactaac
     6781 cacgacgtta aagcggttga gtatttcctg aaagaaaaag tggcggagat cccggaactg
     6841 cacgcggttt ctgaattcat ccactttgcc tgtacttcgg aagatatcaa taacctctcc
     6901 cacgcattaa tgctgaaaac cgcgcgtgat gaagtgatcc tgccgtactg gcgtcaactg
     6961 attgatggca ttaaagatct cgccgctcag taccgcgata tcccgctgct gtcccgtacc
     7021 cacggtcagc cagccacgcc gtcaaccatc ggtaaagaga tggctaacgt cgcctaccgt
     7081 atggagcgcc agtaccgcca gcttaaccag gtggagatcc tcggcaaaat caacggtgcg
     7141 gtcggtaact ataacgccca catcgccgct tacccggaag ttgactggca tcagttcagc
     7201 gaagagttcg tcacctcgct gggtattcag tggaacccgt acaccaccca gatcgaaccg
     7261 cacgactaca ttgccgaact gtttgattgc gttgcgcgct tcaacaccat tctgatcgac
     7321 tttgaccgtg acgtctgggg ttatatcgcc cttaaccact tcaaacagaa aaccattgct
     7381 ggtgagattg gttcttccac catgccgcat aaagttaacc cgatcgactt cgaaaactcc
     7441 gaaggaaacc tgggcctttc caacgcggta ttgcagcacc tggcaagcaa actgccagtt
     7501 tcccgctggc agcgtgacct gaccgactcc accgtgctgc gtaacctcgg cgtgggtatc
     7561 ggttatgcgc tgattgcgta tcaatccacc ctgaaaggcg tgagcaaact ggaagtgaac
     7621 cgtgaccatc tgctggatga actggatcac aactgggaag tgctggctga gccaatccag
     7681 acagttatgc gtcgctatgg catcgaaaaa ccgtacgaga agctgaaaga gctgactcgc
     7741 ggtaagcgcg ttgacgccga aggcatgaag ctgtttatcg acggtctggc gttgccagaa
     7801 gaagagaaag cccgcctgaa agcgatgacg ccggcaaact acattggtcg cgccatcacc
     7861 atggttgatg agctgaaata aactcgtatc agtgccggat agcgatgctg tccggcctgc
     7921 ttattaagat tatccgcttt ttattttttc actttacctc ccctcccccg ctggtttatt
     7981 taatgtttac ccccataacc acataatcgc gttacactat tttaataatt aagacaggga
     8041 gaaataaaaa tgcgcgtact ggttgttgaa gacaatgcgt tgttacgtca ccaccttaaa
     8101 gttcagattc aggatgctgg tcatcaggtc gatgacgcag aagatgccaa agaagccgat
     8161 tattatctca atgaacattt accggatatt gcgattgtcg atctcggatt gcctgacgag
     8221 gatggtctgt cactgattcg ccgctggcgt agcaatgatg tttcactgcc gattctggta
     8281 ttaaccgccc gtgaaagctg gcaggacaaa gtcgaagtat taagtgccgg tgctgatgat
     8341 tacgtgacta aaccgtttca tattgaagag gtgatggcgc gaatgcaggc attaatgcgg
     8401 cgtaatagcg gtctggcttc acaggtcatt tcgctaccac cgtttcaggt tgatctctcc
     8461 cgccgtgaat tatctattaa tgacgaagtg atcaaactga ccgcgttcga atacaccatt
     8521 atggaaacgt tgatacgcaa taatggcaaa gtggtcagca aagattcgtt aatgctacaa
     8581 ctctacccgg atgcggagct gcgggaaagc cataccattg atgtactgat gggacgtctg
     8641 cgcaaaaaaa ttcaggcaca atatccgcaa gaagtgatta ccaccgttcg cggccagggc
     8701 tatctgttcg aattgcgctg atgaaaaaat tactgcgtct ttttttcccg ctctcgctgc
     8761 gggtacgttt tctgttggca acggcagcgg tagtactggt gctttcgctt gcctacggaa
     8821 tggtcgcgct gatcggttat agcgtcagtt tcgataaaac tacgtttcgg ctgttacgtg
     8881 gcgagagcaa tctgttctat acccttgcga agtgggaaaa caataagttg catgtcgagt
     8941 tacccgaaaa tatcgacaag caaagcccca ccatgacgct aatttatgat gagaacgggc
     9001 agcttttatg ggcgcaacgt gacgtgccct ggctgatgaa gatgatccag cctgactggc
     9061 tgaaatcgaa tggttttcat gaaattgaag cggatgttaa cgataccagc ctcttgctga
     9121 gtggagatca ttcgatacag caacagttgc aggaagtgcg ggaagatgat gacgacgcgg
     9181 agatgaccca ctcggtggcg gtaaacgtct acccggcaac atcgcggatg ccaaagttaa
     9241 ccattgtggt ggtggatacc attccggtgg agctaaaaag ttcctatatg gtctggagct
     9301 ggtttatcta tgtgctctca gccaatctgc tgttagtgat cccgctgctg tgggtcgccg
     9361 cctggtggag tttacgcccc atcgaagccc tggcaaaaga agtccgcgaa ctggaagaac
     9421 ataaccgcga attgctcaat ccagccacaa cgcgagaact gacaagtctg gtacgaaacc
     9481 tgaaccgatt gttaaaaagt gaacgcgaac gttacgacaa atatcgtaca acgctcaccg
     9541 acctgaccca tagtctgaaa acgccactgg cggtgctgca aagtacgctg cgttctctgc
     9601 gtagtgagaa gatgagcgtc agtgatgctg agccggtaat gctggagcaa atcagccgca
     9661 tttcacagca aattggctac tacctgcatc gtgccagtat gcgcggcggg acattgctca
     9721 gccgcgaact gcatccggtc gccccactgc tggacaatct cacctcggcg ctgaacaaag
     9781 tgtatcaacg caaaggggtc aatatctctc tcgatatttc gccagagatc agctttgttg
     9841 gtgagcagaa cgattttgtc gaggtgatgg gcaatgtgct ggataatgcc tgtaaatatt
     9901 gcctcgagtt tgtcgaaatt tctgcaaggc aaaccgacga gcatctctat attgtggtcg
     9961 aggatgatgg ccccggtatt ccattaagca agcgagaggt cattttcgac cgtggtcaac
    10021 gggttgatac tttacgccct gggcaaggtg tggggctggc ggtagcccgc gaaatcaccg
    10081 agcaatatga gggtaaaatc gtcgccggag agagcatgat gggcggtgcg cggatggagg
    10141 tgatttttgg tcgccagcat tctgcgccga aagatgaata aatatgtcca tacttcacgc
    10201 attacgttaa gcatccgtta taatcggttg cagataccag cctgtggatg cttaacatgg
    10261 aataccaact cactcttaac tggcccgatt ttcttgaacg tcactggcag aaacgcccgg
    10321 tggtgttaaa acgcggcttt aataatttta ttgacccgat ctctccagac gagttggcgg
    10381 gtctggcgat ggaaagcgaa gtcgacagtc gactggtcag tcaccaggat ggcaaatggc
    10441 aggtcagcca cggcccgttc gaaagctacg atcatctcgg tgaaaccaac tggtcgttac
    10501 tggtacaggc agtgaaccac tggcatgagc cgaccgccgc gctaatgcga ccgttccgtg
    10561 aactaccgga ctggcgtatt gatgacctga tgatctcttt ttccgtacct ggcggcggcg
    10621 tcggcccaca tctcgatcag tacgacgtgt ttattattca gggtaccgga cgtcgtcgct
    10681 ggcgagtggg tgaaaagctg caaatgaaac agcactgccc acatccggat ctgttacagg
    10741 tcgatccgtt cgaagccatc atcgatgaag agctggagcc tggtgatatt ctttatattc
    10801 cgccaggatt cccgcatgaa ggctacgcgc tggaaaatgc gatgaactat tccgtaggtt
    10861 ttcgcgcgcc aaatacgcgg gaactgatta gtggatttgc cgattatgtg ctgcaacgtg
    10921 aactgggcgg caactactac agcgatcctg atgttccacc tcgcgctcat cctgcggacg
    10981 ttctgccgca agagatggat aaactgcgtg agatgatgct cgaattgatc aaccagccgg
    11041 aacattttaa gcaatggttt ggcgagttta tatcccagtc acgtcatgaa ctggatatcg
    11101 cgccgccaga gccgccttat cagccggatg aaatctacga tgcgctgaaa caaggtgatg
    11161 tgctggtgcg cctggggggt ctgcgcgtat tgcgcattgg cgacgatgtg tatgccaatg
    11221 gtgagaagat cgattccccg caccgtccgg cactggatgc gctcgccagc aacattgcgc
    11281 tgaccgcgga gaattttggc gatgcgctgg aagatccgtc attcctcgcg atgctcgcgg
    11341 cgctggtcaa tagcggatac tggttcttcg aagggtaagt ttggatttaa gccggatgcg
    11401 gcatcacatg ccgcatccct tttcgcttac ttccgttgcg ccgtcaactc ggcaatacgg
    11461 acgatcacct gcaccgcttt ttccatacct tccagagtca caaactcatg cttaccatga
    11521 tagttgtaac cgccagtgaa caggttcggg cacggtaatc ccataaacga caactgcgcg
    11581 ccgtcggtac cgccgcggat cggtttcagt tccggttcaa tatcgcagtc acgcatcgcc
    11641 tgctgggcga tatcgagaat atgcggatgc tcaaccactt tctcgcgcat attgtagtaa
    11701 ctgtcttcaa tcaccagttc aatgtagcaa tcaggatgta accctttgcc cacttttttg
    11761 gcgatctcca tcattttacg tttacgcgct tcaaactgtt tacggtcgaa atcacggatg
    11821 atgtagtgca tatcggcccg ttcaacggtg cctttcatgc tcgccaggtg atagaaacct
    11881 tcatagcctt ctgtcatttc cgggctttca tccgccggaa cttccgcatg aatacgtgcc
    11941 gccagcgaca gcgcatttac catcacgcct ttcgccgtgc ccggatgaac attgttaccg
    12001 acaattttga tattgaccga cgcggcgttg aagttttcaa actccagttc gcctacgcca
    12061 ccaccatcaa cagtgtaagc ccagcgggca tcgaaggcgt caacatcaaa atgtttcgcc
    12121 cctttgccca cttcttcatc cggggtaaag gcgacgcgaa tatcaccatg cggaatgttt
    12181 ttttgttgca ataccgccag cgcggtcatg atttctgcaa tacctgcttt gtcatcggca
    12241 cctaacaagg ttttaccatc ggtggtaatc agcgtctgac ccagtagctg atgcagcacc
    12301 gggaacataa ccggtgataa aacttcatcg ccgataccca gcgcaatatc gccaccgcga
    12361 tagttttcaa caatttgcgg attcacattt ttgccgctgc aatccggtga ggtatccaca
    12421 tgagaaataa agccaatcgc cgggatatcg ccagggacgt tagccggtaa cgtcgccatc
    12481 aaagtgccct tctcacttaa ggtcacattg ataagcccca tctcttcgag ctgctctttc
    12541 agcagatgca ataacttcca ttggccttcc gtgctgggaa cctgtctcac ccctgccttt
    12601 gattgggtat ccagagacac gtagttcaaa aatcgctcaa gtagtttatc catgtagtca
    12661 ccctcacttt ttgtgacaac attattaaga agcaagaaaa gacaaatatt gcgtcaggtc
    12721 acttttaccc ctgcaagcgg gaatatttat cagcattacc ttaatgaata taaagctaag
    12781 ccagtaattc acaacaaaga ttggcgattc aagcggtttg ccgtagaatt accgccctca
    12841 ttaagagtca ccaaggtggt taaccacaaa ccccgcatcg gtaagccatc cgttgcgttt
    12901 acatgggaca gagtaaaaaa ttgaataaac aaccgagttc gctttcaccg ctggtgcaat
    12961 tggcgggaat tcgcaaatgc tttgatggta aagaggtcat tccccagctg gatctgacta
    13021 tcaacaatgg cgagttcctc acgctgcttg gcccttctgg ctgcggtaaa acaaccgttc
    13081 ttcgcctgat tgcaggtctg gaaactgttg attccggacg tatcatgctg gataacgagg
    13141 acatcaccca cgttccggcg gaaaaccgct atgtgaatac tgttttccaa agctacgcac
    13201 ttttccccca catgaccgtg ttcgaaaatg tggcctttgg gttgcgcatg caaaaaaccc
    13261 ccgctgctga aattacgccc cgcgtgatgg aagccctgcg gatggtgcag ctggaaacct
    13321 tcgctcaacg caaaccgcat cagctctctg gtggtcaaca gcaacgcgtc gccattgctc
    13381 gcgcggtggt taacaagcct cgtctgttgt tgctggatga gtcgctctca gcgctggatt
    13441 acaaactgcg caagcaaatg cagaacgagc tgaaagcgtt acagcgtaag cttggcatta
    13501 cattcgtgtt cgtgactcac gaccaggaag aagcacttac catgtcggac aggatcgtgg
    13561 tgatgcgcga tggtcgcatt gagcaagacg gcacgccgcg tgaaatctat gaagagccga
    13621 aaaacctgtt tgttgctggg tttattggcg aaatcaatat gtttaacgcc actgtcatcg
    13681 aacgtctcga cgagcagcgc gtacgcgcca acgttgaagg ccgcgaatgt aatatctacg
    13741 ttaacttcgc cgttgaaccg gggcaaaaac tgcatgttct gctgcgcccg gaagacttac
    13801 gtgttgaaga gattaacgac gacaaccacg ctgaagggct gattggttac gttcgcgagc
    13861 gtaactacaa aggcatgacg ctggagtcgg ttgttgaact ggaaaatggc aagatggtga
    13921 tggtcagcga attcttcaat gaagacgatc ctgactttga ccactctctc gaccaaaaaa
    13981 tggccattaa ttgggtagaa agctgggagg tcgtactggc tgatgaagaa cacaagtaag
    14041 ttccagaatg tagtgattgt cactattgtc ggttggcttg tgttgtttgt ctttctgccc
    14101 aacctgatga tcattggcac cagctttttg acccgcgacg acgccagttt cgtcaaaatg
    14161 gtctttacgc tggataacta cacgcgtctg ctcgatccgc tctattttga agtgctattg
    14221 cactcgctga atatggcgct gatcgccacc ctcgcctgcc tggtgctggg ctatcctttt
    14281 gcctggtttc tggcgaagtt gccacacaag gtgcgtccgc tgctgctgtt tctgctgatt
    14341 gttccgttct ggaccaactc attgattcgt atctacgggc tgaaaatttt cctcagcacc
    14401 aaaggctatc tcaacgagtt tttgctctgg ctgggcgtta tcgatacacc aattcgcatc
    14461 atgttcacgc ccagtgcggt gattatcggt ctggtttaca ttctgctgcc gtttatggtg
    14521 atgccgctgt actccagtat cgaaaaactg gataagccgt tgcttgaggc ggcgcgcgat
    14581 ctcggtgcca gcaagttaca gacttttatc cgcatcatta ttccactgac gatgccgggg
    14641 attattgccg gatgtctgct ggtgatgctg ccagcgatgg gcctgttcta tgtgtccgac
    14701 ctgatgggcg gtgcgaaaaa cctgctgatc ggtaacgtca tcaaagtaca gttcctcaat
    14761 attcgtgact ggccgtttgg tgcagccacc agcattacgc tgactatcgt aatgggcctg
    14821 atgttgctgg tttactggcg cgcttctcgt ttgctgaata agaaggtgga actcgaatga
    14881 tcggtcgact gcttcgcggc ggttttatga ccgctatcta cgcgtacctg tatatcccaa
    14941 tcattatttt gattgtgaac tcctttaaca gctcgcgctt tggcatcaac tggcaaggtt
    15001 ttaccaccaa atggtatagc ctgctgatga acaacgacag cctgttacag gcagcgcagc
    15061 attcactaac aatggcggtg ttttcggcga cgtttgctac gcttatcggt tcactgacgg
    15121 cagttgcgct gtaccgttat cgctttcgtg gtaagccgtt cgttagcgga atgctgtttg
    15181 tggtgatgat gtcaccagat atcgtgatgg cgatttcgct gctggtgctg tttatgctgc
    15241 tgggtattca gcttggcttc tggtcgctgc tgttctcgca tatcaccttc tgcctgccat
    15301 ttgtggtagt gacagtgtat tcgcgcctga aaggttttga cgtgcgaatg ctggaagcgg
    15361 cgaaagatct cggtgccagc gaatttacca ttctgcgaaa aatcattctg ccactggcaa
    15421 tgccagcggt agcggcgggc tgggtgttaa gctttaccct gtcgatggac gatgtagtag
    15481 tttcttcgtt tgtcaccggg ccgagttatg aaattctgcc gttaaaaatt tattcgatgg
    15541 tcaaagtcgg cgtatcgccg gaagttaacg cgctggcaac catattactg gtgctgtcgc
    15601 tggtgatggt aattgccagc cagcttattg ctcgtgataa aacgaaaggt aacacagggg
    15661 acgttaaatg aaaaaatggt cacgccacct gctcgcggcg ggtgctctgg cactgggcat
    15721 gagcgccgct cacgccgatg acaacaacac gctgtatttc tacaactgga ccgagtacgt
    15781 gccgccagga ctgcttgaac agttcaccaa agaaaccggt attaaggtta tctattcgac
    15841 ttacgagtcg aacgaaacca tgtatgccaa gctgaaaacg tacaaagacg gtgcctatga
    15901 cctggtggtt ccttcaacct attacgtcga taaaatgcgt aaagaaggga tgatccagaa
    15961 gatcgacaag tcgaagttaa cgaacttcag caatctcgat ccagacatgc tcaataagcc
    16021 gtttgacccg aataacgatt actccattcc gtatatctgg ggggcgacgg cgattggcgt
    16081 taacggtgat gcggtagatc cgaaatccgt taccagctgg gccgatctgt ggaagcctga
    16141 gtacaaaggc agcctgctgc tgaccgacga tgcccgtgaa gtgttccaga tggcgctgcg
    16201 taagctaggc tactccggta acaccaccga tccgaaagag attgaagctg catacaacga
    16261 gctgaaaaaa ctgatgccaa acgtcgcggc gtttaactcc gataaccccg ctaacccgta
    16321 tatggaaggc gaagttaacc tcggcatgat ctggaacggt tctgctttcg ttgcacggca
    16381 gtcgggtacg ccaattgacg tggtgtggcc gaaagaaggc ggcattttct ggatggacag
    16441 cctggcgatc ccggcaaatg ccaaaaacaa agaaggcgcg ctgaaattga tcaacttcct
    16501 gctgcgcccg gatgtggcaa aacaggttgc tgaaactatc ggttatccaa cgccaaacct
    16561 tgcggcgcgt aagctgttaa gtccggaagt ggcgaacgat aaaacgctct acccggatgc
    16621 tgaaaccatt aaaaatggtg aatggcagaa tgacgttggc gtagccagca gcatttatga
    16681 agagtattat cagaagctga aagcaggacg ttaattcagc aagcgggcgg tggtattacc
    16741 gcccgttttt tatttagcaa ggatgtggct aatgagtcag gacagtaaag ttttctttcg
    16801 tatattcttc ggtatcggtc tggtactgat cctcatttct gttgttatct tttataacca
    16861 gttcacctat agcaaagacg cgattcatac tgaaggcgtc attgttgata ccgtctggca
    16921 ctccagtcat tctcatcgca cgggtaaaaa tggttcgtgg tatcccgtcg ttgcctttcg
    16981 tccgacgcca gattacacgc taattttcaa ttcgagtatt ggcagcgatt tttatgaaga
    17041 cagcgaaggc gataaagtta atgtttatta ttctccagga catcctgaaa aggctgagat
    17101 aaataacccg tgggttaatt tttttaaatg ggggtttatc ggcattatgg gcgttatttt
    17161 tatcgccgtc ggtttattaa tcagtatgcc ctcctctaaa aagacacgca ggaaacggaa
    17221 gtcccgccca tgaaaaaaat catgatactg ctcagtttac tgatgttcct gcctctgacg
    17281 gcaatcagta agcccttaat tccaataatg aagacacttt ttacggatgt taccggtact
    17341 gtaccagatg ctgaagagat cgcgcataaa gccgaacttt ttcgccaaca aaccggagtt
    17401 gtaccgttta ttgtggtttt acccgacatt aataatgaag ccagtctcag gcaaaatggc
    17461 aaagcgatgc tggcgcatgc ggcatcttca atgagtaatg taaaaggaag tgttctgtta
    17521 ctctttacta cccgcgagcc acggttaatt atgataacca acggccaggt cgaaagcagt
    17581 atggacgata aacatctcgg ccttctggta gaaaatcaca ctctggctta tttacatgta
    17641 gatctctggt atcagggaat caataatgca ttggctgttt tacaagcaca gatattaaaa
    17701 caaccgacgc cgccactgac atattatccg catcccggac aacagcagga gaatgatcct
    17761 cccggcagta ccacgacatt aggccttttt gcctgggcgg ttgcattcat cgtctttacg
    17821 gcatttttta actacacgac gcgccttaat tatgcattaa agtttgcagt ggcgatgact
    17881 gttgccaata tgggctatca ggctttatgc ctgtatatcg ataatagctt tgcaattacc
    17941 agaatatcgc cgctctgggc agggctgatt ggtgtctgta cgtttattgc cgcgttgtta
    18001 ttgacgagta aacggtaaaa gaggcagtaa agtgtgcgtc tattatgccg gatgcggcgc
    18061 gaacgcctta tctggcccac aaaacccgca aattcaatta attgcgtccc cttgtaggcc
    18121 tgataagcgt agcgcatcag gcaatgcttc ccgctttata agcccttcag caacttttca
    18181 acaaattctg gcaccacctg gcttgccggg ccgtaatatt tctcggcgaa ttcattaccg
    18241 acctgacttg gttcaagatt cagttccacg gtgtgcgcgc catgcagttt cgcttcgtga
    18301 acaaacccag ccgctggata aacatgcccc gaagtaccaa tggcaatgaa aatatcggcc
    18361 atcgacaacg ccatataaat ttcatccatg ccgagtggca tttcgccaaa ccacactacg
    18421 tgcggtcgca agggtgccgg gaactggcag caatggcatt tatcttctgg ggtaacgtct
    18481 ccggtccagt cgagaacctg accactttgt gaacaacgaa ctttcagcag ttccccatgc
    18541 atatgaataa cattggtgtt accggcacgc tcatgaaggt tgtcgatatt ctgcgtcacc
    18601 agcaaaaagc gatcgccgag ggcgtcttgc agtttagcca gcgcaagatg cgcggcgtta
    18661 ggctgaattt ctggctgctg cagctgtcgg cgacgggcgt tataaaacgc ttgtaccagt
    18721 tcaggatcgc gatcgaaacc ttccggcgtt gccacatctt caacccgatg ttcttcccac
    18781 aggccatctg cggcgcgaaa ggtacgaata cctgattccg cagaaatccc tgcccctgtc
    18841 agtacgagta ctcttggttt ttccattgct tccggcacca ctttatctct gaaaaaaata
    18901 cgctgacgca aacgctcgcg cagacggcgt ttatttttac gaaaacgact taaccgatga
    18961 ccccgacgcg acagcatagc aacctctgtt gattaatcgg ttagatgtag gaaggccgca
    19021 ccacgcattc cccccgcatc accgtggcgc gcgcgttcaa tgcgcggaac acgagctaca
    19081 ggtaagagat gacgaggcag cctgtccgcc agttgcgttg tgattgccgg gaaattcgat
    19141 aagccaccac caatgacgac caggtcaggg tcaacaatgg tcaggatatt tcccagacaa
    19201 accgctaata aatccagata acgctcaacg tgcgcccttg cctgctcatc gccttgatca
    19261 taaagcgcaa tgatctcagg agcctgcaac ggttgatgat aatagtgttg atacagccac
    19321 gcaaaaccgc gaccagacag ataattttca atgcagccat gctgaccaca gccgcagcgg
    19381 cgtaacggga aatccaaccc catcatggtt aacgcatcaa ccggcagacg catatggcca
    19441 aactcgccgg taatgtagct tttaccggta atcggtttgc cgttgaaaat cagcccaccg
    19501 ccaacgccgg tgccgagaat caaccccatc accagtggat attgagtaaa ttcatcatcc
    19561 caggcttctg aaagggcaaa acagttggca tcgttatcaa ggcgtacatc gcgatcaaga
    19621 cgtgcgctca ggtcggcacg cagcggttta ccgctggcag cggggacatt ggcggcatac
    19681 agcgtaccat cttctgtttc cggcattccc ggaataccga tgccgacaga gcctttacag
    19741 ccaaaacgtt ggtcagcttc agctaccagc tcacacactg catctaaaaa tgcgtcatag
    19801 ctgtcacgcg gtgtcggcac ccgcttttcc cactgcaact gccgaccgct atcaaacacg
    19861 cctagcgcaa tttttgttcc accaatatca aacccgtaat acattgccgc tccttgtttt
    19921 aatgtactgc ctttactggc cgctaaggac tcgcgcaggg tcaatattac tggcgcgccg
    19981 cgccggatac caacttgcca aaagactcaa caacaatgct gtgaccagta cgtagaagac
    20041 gtccagccag tgcaattccg atggcaggaa gtcaataaaa tagatatcgc tggagaggaa
    20101 ctgatgaccg atcagctttt caatccgctc aataatcggg gtaagttgca gtgaaaccac
    20161 tacgccgata atcaccccac acaggctgcc gaacagccct gccagcaatc cataccagac
    20221 aaagatggcg cgaattaaac catctttcgc ccccagcgtt cttaatactg cgatatcgcc
    20281 actcttgtct ttcaccgcca tcactaaggt ggagacgatg ttgaaacagg ccacgccaat
    20341 caccagtacc atcgccagat acataatggc gcggatcatc tggatatcgc gatacatata
    20401 gccgtaagta ccaatccagc ttttaatata aacatagctg ttggtcactt cacccgcatc
    20461 gcgtaccagc ttattggcgt tgaaaacatc cgtcatttta agggcaatac ctgacacgct
    20521 ggaacccata tcaagatatt gttgggcatc cgccagcggg atcatggcaa aactgtgatc
    20581 gagttgacca ctcaactgca aaataccggc aacgtgcaaa cgcacacgtt ttggctgcat
    20641 cagtttatgc tcgggattcg agttggggat cataatcgat acccaatcgc cctgcttcac
    20701 tttcagcgca tccgccacgc ctttgccgat gataatttgc tgttcgcccg ctttaaaatt
    20761 gcgccacgca tcgccctgga caaacgaggg taatgcgctc agacgctgtt cctgttgcgg
    20821 gttaacgccc ttcacctgga ttgcgcgcag attggcacca ctttctacca gtccggtgaa
    20881 attgatatac ggcgcagcgg cggcaatacc cggcactttc tgcacgttat ccagtgcttc
    20941 ctgccagtta gtccacggct gatccaccgc ttcgatttca ccatgcggca ccaccgccag
    21001 aatgcggtta ttcagttcgc gttcaaagcc gttcatcgcg cttaagccga cgatcaatac
    21061 cgccacgccg agggcaatgc cgatggtaga aatgacggag atcagcgaca ccatgccgcc
    21121 gcgccgccgt ccgcgactaa aacgcaggcc aattaataac gataaaggca tcgccattac
    21181 tccgccccca tcaggctcag ttccgccgtc agacgaccat cacgcatctc cagttggcgg
    21241 ctcatacgtt tcgccagttg caggtcgtga gtaaccacca ggaaggcggt gccctgcaaa
    21301 cgattcaact ccccaagcaa ctggaagatg ctgtcggcgt tacgcgcatc gaggttaccg
    21361 gtaggttcat ccgccagtac cagacgcggg ttattgacca gcgcacgggc aatcgccaca
    21421 cgctggcgtt cgccgccaga aagttcagat gggcggtgat tcgcacgatg ctccagaccc
    21481 accgctttta acatctccag tgcacggctg ttgatttcag cgggcttttt cttgccaatc
    21541 agcagcggca tagccacgtt ttccagggca gtaaaatccg gcagcaggtg gtgaaactga
    21601 taaataaagc ccagcttctg gttgcgcagt tctgctttcg ccgccgaaga cagtttgctc
    21661 atcggttgac cgttaaagat cacatcgccg gaggttggcg tatccagccc gcccagcagg
    21721 tgcagcaagg tgcttttacc ggaaccagag ctaccgacga tcgccatcat ttcaccttcg
    21781 ccgacgctga aactgacatt gtgcagtaca tcggtttgca cactgccttc ctgatagcgt
    21841 ttgcacaggt tgtcgcattg caacaggatc ttattcataa cgtaaagcct cagcgggttg
    21901 tgtggcggca gcgcgccatg aagggtaaag cgtagacagc agcgcgatag ccatcgccac
    21961 cagcgcaata acaatgacct gtaaaggttc gatagcgacc ggcagcgccg cgccatcaag
    22021 caggacgccg attatcggca tcaggttatt taactggctg gcaagcagtg caccaagcgc
    22081 cgctccgagg atcgcaccga taatcccggc gctggcccct tgcaccataa agaccatcat
    22141 gatttgtcgc ggagttaagc cttgcgtttg caggatcgcg acttcgccct gcttctccat
    22201 caccatcagc cccagcgagg taataatgtt aaacgccgct acggcaacaa tcaggctcag
    22261 cagcaagccc atcatatttt tttccatgcg aacggcctgg aacagctcgc ctttacggtc
    22321 acgccagtcc tgccatttgc tgccttcagg cagtttttgc tgacttaaag agtcaacttt
    22381 cagcggctca tccagccaca aacgccagcc ggtaatattg cctgccggat aacgcatcag
    22441 acgcgaggca tcctcaatat tcaccagcat ttcatagcca tcgacttcac tgttggcggc
    22501 gaaagtgcca atcacattga acaggcgctg gcttggaata cgccccatcg gcgtgaactg
    22561 gctggcagat ggcaccatca cgcggatttg atcaccgcga ttgacgccca actgtgaggc
    22621 aagctgttca ccgaggatga cattatattt ccccggctcg aggtcagttt gtttcacatt
    22681 gaccagatac ggcgttagtg gatctttttg cgccgggtcg atacccagca tcaccccgac
    22741 cgccacgctg cgcgcgcttt gcagtaccac atcaccggta gtaataggtg cgacgcgatt
    22801 aacgccgtcc agtttgactg ccgtttccgg gagttgctgc gggttaagag agccatgctc
    22861 agaagagaga attgcctgtg gcatcaggcc aaggatgttg ttttgcagct cgcgctcaaa
    22921 gccgttcatc actgacaata ctgtgaccag cgccatcacc ccgagggtaa tgccgatggt
    22981 agaaagccag gagacgaaac gaccgaagcg atccgctgca cgcccacgca tgtaacgcag
    23041 gccaataaat agagcgacag gttggtacat gaaatccgtc tggttgctgt agcaaagaca
    23101 cgagtatata agcgaaagcg ggatgggtaa acgtctgaac tgtaagtgat cgtcagggct
    23161 aatctgaaaa gtaccagcaa atcaatcgac taaagggcct cattatctca ttggccttgt
    23221 ggcctgatct ttatctgaaa aataaccaaa tacagacaga tacgcattac accacgcgac
    23281 tggcccctca ggatcaacag catgttaaat aaaaagagcg tgttgtcctg atgaaacaaa
    23341 aagagctatg gattaaccag atcaaagggt tatgtatttg tctggtggtg atttatcact
    23401 cggtcattac cttttatccg catctcacca cttttcagca tccgttatcg gaagtcctga
    23461 gcaaatgctg gatctatttc aatctttacc ttgccccctt tcgtatgccg gtttttttct
    23521 ttatttccgg ctatttgatt cgccgctata tcgacagcgt accgtgggga aattgtctcg
    23581 ataaacgcat ctggaacatc ttctgggtgc tggcgctttg gggcgtggtg cagtggctgg
    23641 cgttaagtgc gttgaaccag tggctggcac ctgagcgcga tttaagcaat gcctccaatg
    23701 ccgcgtatgc cgattccacc ggtgagttcc tgcacgggat gatcaccgcc agcaccagtt
    23761 tgtggtatct gtatgcgtta attgtctatt tcgtggtatg taaaattttt agccgtctgg
    23821 cgctgccact attcgccttg tttgtactga tgagtgtggc ggttaatttc gttcccacgc
    23881 cgtggtgggg aatgaacagt gtgatccgca atttgcctta ttacagcctt ggcgcatggt
    23941 ttggcgcaac attaatgacc tgtgttaaag aggtgccgtt gcgccgccat ctgctgatgg
    24001 cttctttgct gaccgttctg gcggtcggtg cctggttgtg tactatctcg ctgctgttgt
    24061 cgctggtatc gattgtggtg atcataaagc tgttttatca atacgagcaa cgtttcggta
    24121 tgcgctccac cagcctgctg aatgtgattg gttccaacac cattgctatc tacaccaccc
    24181 atcgcattct ggttgaaata ttcagcttaa ctctgcttgc gcaaatgaac gcagcacgct
    24241 tgtcgccgca agtcgaactg acactcctgc tggtttaccc ctttgttagt ttgttcatct
    24301 gtactgttgc gggcttgctg gtaagaaaac tttcacagcg cgcattcagc gatctgttgt
    24361 tctccccgcc ttctctgccc gcggccgtca gttactcccg ctaagccatc gccccagccg
    24421 gggcgattca atttgctaaa ccatgtcgat tacggataat gaacagcatt gcttatcaga
    24481 gatatgcccc catatgttga ggcgtatcct aacgagaatc tgacaaccgt tatgcctgaa
    24541 caatatcgtt atacgctgcc cgtcaaagcg ggtgagcagc gtctgctggg cgagttaacc
    24601 ggcgctgcct gtgcgacgct ggtagcggaa attgccgaac gtcacaccgg accggtggtg
    24661 cttattgcgc cagatatgca aaatgctctg cgtttgcatg atgaaatcag ccagtttacc
    24721 gatcagatgg tgatgaatct ggcggactgg gaaacccttc cctatgacag tttttcgcct
    24781 catcaggaca ttatctcctc gcgcctttcc accctttacc agctaccgac gatgcagcgt
    24841 ggcgtactga ttgttccggt gaatacgctt atgcagcgcg tttgcccgca cagttttctc
    24901 cacggtcatg cgctggtgat gaaaaaaggt cagcgcctgt cacgagatgc attacgaacc
    24961 caactggaca gcgccggtta tcgccatgtt gaccaggtga tggagcacgg cgaatacgcc
    25021 acgcgcggcg cgttgctgga tctcttcccg atggggagtg agctgcctta tcgtcttgat
    25081 ttctttgatg atgaaatcga cagcctgcga gtgtttgacg tcgatagcca gcgcacgctg
    25141 gaggaagtag aagagatcaa tctgctgccc gcgcacgaat ttccgaccga taaagcggca
    25201 attgaactgt tccgcagcca gtggcgtgat accttcgaag tgaagcgcga tccggaacat
    25261 atttatcagc aagtgagtaa aggcacatta cctgccggga tcgagtactg gcagccgcta
    25321 ttcttcagcg aaccgctgcc gccactgttc agttatttcc ctgccaatac gctgttggtg
    25381 aatactggcg atctggaaaa cagtgccgaa cgtttccaga ctgacacgct ggcgcgtttt
    25441 gaaaatcgcg gcgtcgatcc gatgcgcccg ctattaccgc cacaatcgct ctggctgcgc
    25501 gtggacgatc tcttctcaga gctgaaaaac tggccgcggg tgcagctaaa aactgaacat
    25561 ttaccgacaa aagcagcgaa tgccaattta ggttttcaga agctgccaga cctggccgtt
    25621 caggcacaac aaaaagcgcc gctggatgcg ctgcgtaagt tcctcgagtc tttcgacggt
    25681 ccggtggtgt tctcggtaga aagtgaaggt cgccgtgaag cactgggtga actgctcgcg
    25741 cgaattaaaa ttgctcctca acgcattatg cgtcttgatg aagccagcga ccgtgggcgt
    25801 tatctgatga ttggcgctgc cgaacatggt tttgtcgata cggtacgtaa tctggcgctg
    25861 atctgcgaaa gcgatctgct cggtgaacgc gttgcccgcc gtcgtcagga ttctcgccgc
    25921 gccatcaacc ccgatacact gatccgtaac ctcgcggagc tgcatattgg tcagccggtg
    25981 gtccatctgg agcacggtgt cggtcgttat gcaggaatga ccacgctgga agcgggcggc
    26041 attactggcg agtacctgat gctcacctat gccaacgacg ccaaactgta tgttcctgtg
    26101 tcgtcactgc atctgattag ccgttacgca ggtggcgcgg aagaaaacgc cccgctgcat
    26161 aaacttggcg gcgatgcgtg gtcacgcgcg cggcagaaag cggcggaaaa agtgcgtgat
    26221 gtggcggcag aattgctgga tatctacgcg caacgcgccg ccaaagaggg ctacgcgttt
    26281 aaacacgatc gtgagcagta tcagttgttc tgcgacagct tcccgtttga aaccacgccg
    26341 gatcaggcgc aggccattaa tgcggtgctt agcgacatgt gtcagccgct ggcaatggat
    26401 cgtctggtgt gcggcgatgt tggctttggt aaaacagaag tggcgatgcg cgccgctttc
    26461 ctggcggtag ataaccacaa acaggtggcg gtgctggtgc ctaccaccct tctcgcgcag
    26521 cagcattacg acaacttccg cgaccgtttc gccaactggc cggtacgtat cgaaatgatc
    26581 tcccgtttcc gcagcgccaa agagcagacg caaatccttg cggaagtggc ggaagggaaa
    26641 atcgatattc tgatcggtac gcacaaactg ctgcaaaatg acgtcaagtt taaagattta
    26701 ggtctgctga ttgtcgatga agaacaccgc ttcggggtgc gtcataaaga gcgcattaaa
    26761 gcgatgcggg cgaacgtgga tattctgaca cttaccgcaa cgccgatccc acgtacgctg
    26821 aatatggcaa tgagcggaat gcgtgacctg tcgattatcg ccacgccgcc cgcccgtcgt
    26881 ctggcagtta aaacctttgt ccgtgagtat gacagcctgg tggtcaggga ggcgatcctg
    26941 cgtgaaattt tgcgcggggg gcaggtttat tatctttaca atgatgtgga aaacatccag
    27001 aaagccgccg aacggctggc agaactggta cctgaagcgc ggattgccat cggtcacggg
    27061 cagatgcgtg agcgcgaact ggaacgggtg atgaatgatt tccatcatca acgtttcaac
    27121 gtgctggttt gtaccaccat tatcgaaacc gggatcgaca ttcctaccgc caacaccatt
    27181 atcattgaac gcgcggatca cttcggtctg gcacagttgc accagttgcg cggtcgcgtc
    27241 ggacgttcgc atcatcaggc atatgcatgg ttgctgacac cgcatccaaa agcgatgact
    27301 accgatgcac aaaaacgtct tgaagcgatt gcctcgctgg aagatctcgg ggcaggtttt
    27361 gcgctggcaa cgcacgatct ggagattcgc ggcgcgggtg aactgcttgg cgaagaacaa
    27421 agcggctcaa tggaaaccat cggtttctcg ctgtatatgg agttgctgga aaacgccgtc
    27481 gatgcactga aagccggacg cgagccgtcg ctggaagatc tcaccagcca gcaaacagaa
    27541 gtcgagctgc ggatgccgtc gctattgcca gatgatttca tccctgacgt gaacacgcgt
    27601 ctgtcgttct acaaacgtat tgccagcgcc aaaacggaaa acgaactgga agagatcaaa
    27661 gtcgagctta tcgatcgctt cggcctgctg ccggatccgg cgcgtaccct gctggatatt
    27721 gcccgtctgc gccagcaagc gcagaaactg gggatcagga agctggaagg taatgagaaa
    27781 ggcggcgtga tcgaatttgc cgagaagaat cacgttaatc cggcctggtt gattggtttg
    27841 ctgcaaaaac agccgcagca ttaccgtctt gatggtccga cgcgcctgaa atttattcag
    27901 gatttgagtg agcggaaaac gcgtatcgaa tgggtacgcc agtttatgcg tgaactggaa
    27961 gagaacgcga tcgcttaatg gtaaatcggg ggcgtttctg cgcccccatc tgcaacattt
    28021 acaaattctt tgcacttccc tgcactatcc gacactgtca ccctccataa ttcagactta
    28081 tctttttatt acaataacct tatatttatt atggactttg gtgatgatca aaacgcgttt
    28141 ttctcgctgg ctaacgtttt ttacgttcgc cgctgccgtg gcgctggcgc taccggcaaa
    28201 agccaacacc tggccgctgc cgccagcggg cagtcgtctg gttggtgaaa acaaatttca
    28261 tgtggtggaa aatgacagtg gctctctgga agcgatcgcc aaaaaatata acgtcggctt
    28321 tctcgctctg ttacaggcca accccggcgt tgatccttac gtaccgcgcg cgggtagcgt
    28381 gttaacgatc ccgttgcaaa ccctacttcc agacgcgccg cgcgaaggta ttgtgatcaa
    28441 cattgcggag ctgcgtctct attactaccc gccgggtaaa aattcggtaa ccgtgtatcc
    28501 catcggcatt ggtcagttag gtggtgacac gctgacgcca acgatggtga ccaccgtttc
    28561 agacaaacgt gcaaacccaa cctggacgcc aacggcaaac attcgcgccc gttataaagc
    28621 acagggaatt gagttgcctg cggtagtgcc ggctggaccg gataatccaa tgggccatca
    28681 tgcgattcgc ctggcggcct atggcggcgt ttatttgctc cacggtacga acgccgattt
    28741 cggcattggc atgcgggtaa gttctggctg tattcgtctg cgggatgacg atatcaaaac
    28801 actctttagc caggtcaccc caggcaccaa agtgaatatc atcaacattc cgataaaagt
    28861 ctctgccgaa ccaaacggtg cgcgtctggt tgaagtacat caaccgctgt cagagaagat
    28921 tgatgacgat ccgcagctgc tgccaattac gctgaatagc gcaatgcaat catttaaaga
    28981 tgcagcacaa actgacgctg aagtgatgca acatgtgatg gatgtccgtt ccgggatgcc
    29041 ggtggatgtc cgccgtcatc aagtgagccc acaaactttg taaatcctgg ataaaaaaaa
    29101 tccccgcgac acggcatgtc gcggggaaaa aaatcagcag tagcaggcat taatgagggt
    29161 taatgcttat ttataaatta ctgctgttcc atggagggta ttcggaccgg ttacagaagt
    29221 aatacggaaa gattttgcgc ccatctcatc cgctttttgc gccagctgct cttccagcga
    29281 tcccagattt gtccccgcat tagcactgat agtaccgact ttttgttggc cttctggcgt
    29341 tgactgaact tcgacagccg caaagctggc aaatgacatt gagcttaaaa tcgccgcagc
    29401 gatgagggtt tttacgtttt tcataatagt ggccttatgc agatgaatga cgtcgcaagc
    29461 aattacttaa cgatcgataa ctaaatgata gatgtgatct ggatcacata caagatattt
    29521 tttataacaa tcattaatta atttaaaaat ctttaaattt cagttaaata gaaagcgatt
    29581 atttttatgg tttctggact ggtgaacgga ggtgattatt tttataataa cctttaattc
    29641 acagtcacca ggtacaacgg catcatggca actgactcaa cacaatgtat aaaaaaaagc
    29701 cgtggccgcc caaaagtgtt cgacagggat gccgcgcttg ataaggccat gaaattgttc
    29761 tggcagcacg gttatgaagc gacttctctt gcggacctcg ttgaagcgac cggagctaaa
    29821 gcgcccacgc tatacgcgga atttaccaac aaagaggggt tattccgcgc cgtactcgac
    29881 cgctatatcg atcgttttgc cgctaagcat gaagcacagc tgttttgtga agagaaaagc
    29941 gtggagtctg cgctggctga ctattttgct gccatcgcca actgctttac cagcaaagac
    30001 actccggctg gctgcttcat gatcaacaac tgcaccaccc tctccccgga ttcaggagat
    30061 atcgccaata cgctgaaatc acgccatgcg atgcaagagc gcactttgca gcagttttta
    30121 tgtcaacgac aagcgcgcgg ggaaatcccg acccactgtg acgtgacgca tctggcagaa
    30181 ttccttaatt gtattattca ggggatgtcg atcagcgcac gcgaaggtgc atcgcaggaa
    30241 aaactgatgc agattgcccg aacgactttg cgtttatggc cggaactgct gaaataggtc
    30301 gcaaaaaaag cccctcagct tgagcgaatg aggggctaaa ttgcagagta caaccttgtt
    30361 atgctttgtt attcaaaatc agctgcccgt tgctatctag cgggatctgc gtacccggat
    30421 cgcggtccat tcggattttg ccctgctgat cgccaatctt ataggtcaca tcataaccga
    30481 gcattttttc tgacttgtca tacaccgttt tacaacgctg ttgcgtagtc gtgtaagtat
    30541 cactttcctg gagagagccc tggatctggt taccggcata tccaccaccc agcgccccca
    30601 caacagtagc gacatcttta ccgcgaccac caccaaaccg atgccctatc acgccaccag
    30661 caacagcgcc gagcaccgac ccggtaatgc gattttcatc ctgcaccggt cgacgatggg
    30721 tcactgtgac gttgcgacac tcctgacgcg gtgttttaac cgtttccttg attggggttg
    30781 cagaaacaac ctgagcgtat tgcgggccac gttcaaacac gttcagactg gccactgccg
    30841 ctacgcccag cgcagctgcg acaccaatcc cgatacccgc caacattgat ttattcacgg
    30901 gaacacctcc ttctttgctg ttatgccaat catgcaagcg aaggagaaaa gcagctatca
    30961 gacagaagat gaaaagcgcg agaatggctg gaaatactta aggattcgga ggagtctgaa
    31021 ggaatgcctg atgcgacgct taacgcgtct tatcaggcct accgctcgta ccatttgtcc
    31081 agggcggatg aggcgtttat gccccatccg ccagtacaag ccgattaatg caacttcaaa
    31141 cgtgggcgga taacgcggtt aatactcccc accagcatca ttaatccggt tttaaagtaa
    31201 ccatgcagcg caatctggtg cattcggtac aacgagatgt atacaaagcg cgcaattcgt
    31261 ccttcaatca tcattgagcc gcgcgtcagg ttacccatca ggctaccgac ggtggagaag
    31321 ttcgacagcg ataccagaga accgtgatct ttatactgat aacttttcag cggcttaccg
    31381 ttcatctgcg ccagaatgtt gttcattgcg caagttgcca tctggtgtgc agcctgagcg
    31441 cgcggcggaa caaagccccc ttccggacgc gggcatgacg cgcaatcgcc aatagcgtaa
    31501 atgtctggat cgcgggtggt ttgcagcgtc ggttccacca ccagctggtt gatacggttg
    31561 gtttcaagac caccgatatc tttcaggaag tctggcgctt tgatcccggc tgcccacacc
    31621 atcagatcag cctcaatata ttcgccatct ttagtatgca ggccgccttc atcagcactg
    31681 gtgaccatgg tttgcgtcag cacgcgaacg ccaagtttcg ttaactcact atgggccgca
    31741 gcagagatac gtggcggcaa tgcaggcaaa atacgttcgc ccgcttctac cagcgttacg
    31801 ttcagggctt cgttggtcag acctttatag ccgtagctgt gcagttgctt gaccgcgttg
    31861 tgcaattcag cggagagttc tacacccgtc gcgccgccgc cgacaatcgc aatgttcact
    31921 ttgccattcg cgcccaggtt ggcggagtat ttcagaaaca gattcagcat ctcctggtgg
    31981 aagcgacgcg cctggtgcgg attatcgagg aaaatgcagt tctctttgac acctggcgta
    32041 ttgaaatcgt tagaggtgct acccagcgcc attaccaggg tgtcataggc gattttacgt
    32101 tccggaacca gcaattcacc tttttcgtcg cgcagttctg caatagtgat tgttttcgct
    32161 tcacgatcaa tatcaatgac ggaacccagc tggaactgga aaccatgatt acgcgcatgg
    32221 gccagatagc tcaacgcatc gacgccttca tcaagcgagc cagtcgccac ttcgtgcagc
    32281 agcggtttcc acaggtggct gtggttacga tcgaccagcg taattttggc ttttttcttg
    32341 cgtcccagct tatgccccag ctgtgttgcc atttccagcc caccagcacc gccgccgaca
    32401 atcacaattt ttttcaatgg cgtagtcaac gtgaccccct taaatttatt aaccaattgt
    32461 taattaatgg ttattggcat agctcttaat taacaacagg ttacagcaat gaaaatgttc
    32521 ttcgctaatg agaataacat gaatggtgca ttggtcatac caaaattgat gttaatcaag
    32581 ttttgttgct gaaaagatag gcgactttac cgggtgagat caaaaaacag agtttgttgt
    32641 ttattatttg agctgatttg tgagaatgat atagagtgag gtgtgtatgg agggcgtttg
    32701 gtagtcctga taagaagcgc atcaggcatt gatgctcgac tgtcggatgc ggcgtgaacg
    32761 ccttttccga cccacagaat ccggagcgca tcaggtaccg gcaaggttac ctgatgcgac
    32821 gagggcattt acccgagggt tttgaacgct ttaatgcgct gtaaatgcgg ggagatattc
    32881 ttgaatttgt gcgtctgctc ttcgtcccag acaatctcgt aataatgatg caactcttca
    32941 gatgtccgct ggctgttaag cgcttcatca ttacgcgaca aaatcaccag gcaacgatcg
    33001 cgattctttt cgcggaagtt ggtcacacac ttagtggcaa tatcggcata ctcttccggg
    33061 cgatcaatct tgccttccat gttctcataa gggaacaaat tagggttgaa gatcacctgg
    33121 cggatatcgc aaagaaaacc aatccgttcc gcccagtatc cgcccagacc aacgccgcaa
    33181 atcagcggac gctcgtcgac gttcagttgc aacattttgt ccacttcttt gagcagatgc
    33241 tgcatatcat gtttcggatg ccgcgtactg tagcttatta gccgtacatc cgggtcaata
    33301 aactgcaatt gtaagacttt ctcgtggtta cccggactgt tagagtcaaa accgtgcaaa
    33361 tagataatca tcgcttcctc acataagcca gggttaatga cctgccttct cttcctgcca
    33421 gcgttcatgt aactgattca gacgggcgct gatcgctttc cagcgagccg agtccatcag
    33481 ttcctgtcgc gaaaatgaac ctttatgata caaacgtgta acacgttctg ccttgatcgg
    33541 tgacagatta tctaacacgc tgacggcccc tttacgatta ttgcagacca ggatcatatc
    33601 gcaacctgca tccagtgatg cctgtccacg ctcggcataa ctgcccataa tcgctgcgcc
    33661 ttccatcgat aaatcgtcag agaaaatcac gccgtcaaaa cccaattcct gacgcaaaac
    33721 ggttttcagc cagtagggag aaccgctcgc cggacgcgga tcaacatcac tgtagatcac
    33781 atgcgcaggc ataatggcgt cgagtttatt ttcgcggatt aaggaactga agaccgacat
    33841 atctttagcg cgaatctccg cttgcggacg tgggtcacac ggtgtttctt tgtgtgagtc
    33901 tgccgttact gcaccgtgtc ctgggaagtg tttcccggta gttttcattc cggcttcatg
    33961 cataccatca ataaaccggc tggcaattgc cagggctttt tcgggatcgg catgataaga
    34021 acgctcgcca atcgccgcgc tgatatgccc gacgtccagc actggcgcaa agctgatatc
    34081 aatatccata gcaatcattt cgctggccat caaccaacct gcctcttgcg ccagttttcc
    34141 gccttcttcc attcccaaca gcgcagcaaa tgattgtgcc gctggcaagc gggtaaaacc
    34201 ttcacgaaaa cgctgcacgc gtccaccttc ctgatcaacc gccaccacca gatgattgcg
    34261 cgaagctgcg cggatctggc gcaccagttc acgtaactgg gcaggatcat gatagttacg
    34321 cgtaaagaga atcagccctc ccaccagcgg atgcgccagt atttcacgct cttccgcgtc
    34381 cagttcgtaa ccttcgacat ccaacattac tggacccaca ctgctctcct tattgtttta
    34441 ttaatagctg ccgccaggtg tcatcggcca gcctgataaa ttgttgatcg ccggtttgtc
    34501 gccagcggta ctcaaaccac cctgctttga gcatcagcag ccagggaaac catcgcctga
    34561 cctgacgcca taattgcgcc ggataaatct tcgcgcgagt ggcatagtca ttgaccaatt
    34621 gccgatgctg gtcagtattt tccacccaca ccgccgccag ttccagcgcg atatcaccat
    34681 ctccggcata ctcccagtcg atgagtttta accctgacgc gctatgcact aaatttccgg
    34741 cgtggacatc catatgcaat ggacttaagc gtaaaggccg tggttcccgc gctttgcgca
    34801 gacgttttaa cattcgcagc caacccactg tccgcctcac cggatcgctt tgctgccagt
    34861 acagttccag taacggcaac agcgttattc gccagccaaa acgcggttgt tgatgtagat
    34921 aatacagcaa gcctgccagt tcgttggtat ccggcaaata cgtttttacc tcgccgggca
    34981 gatagtcgac caccatccag tcacggagat ataaatgcgg cttcggtgca atgcatgcgg
    35041 gtagttgtga taaagcccga tactggcgca agaacgcgaa ccgcggcgca tcaggatcgt
    35101 gcggctgacg cacaacaaaa cgctggccct gatgttcaat gagaaaactc ccgccactaa
    35161 gcccactatt aaacgtcgtg acgggatgaa attgcgggaa aaagcacgac agcaattcgt
    35221 cgcgcgtgat gggattattg ctgcgaaacg gcacctttac ctgaccagat aatttcgccc
    35281 gtctgcacca gcatcagctg catttgtagg gtcggagcgt taacgttgcc agaggcgctg
    35341 gagtacagca cgtaatgagc gccgacattg cgggcaatgc ctatggcttt actacgggta
    35401 cctaaactgt cctgcggcga caaacctaac tgttgcttcg ccatcgacag ctgctgggcg
    35461 gaaaccaggg taaatttacc gttattagcc agcgcatttc gcagcgtttc ggtcgcttct
    35521 gcggcattca gcgaaccgtt agtacggttg ttaacgctat caaccagcag gacgctaccc
    35581 gcagtcacgc catcagcccc aagcatctta ctgaccatcg gctgcattgc gccattccag
    35641 tcataatggc gaatatgcgg cgcaggcggt gcagtttgat cttcgtgctc aattgggcct
    35701 ggctgctgcg gtatcgtcgg caccgatggc actgtgggga caggctgttg cggctcggct
    35761 ggttgttccg gcgctggttt cacttcttct accggcgcag gttcacgttg ccccacacac
    35821 ccggcgagaa acatcgccag cgcggtaatc aaggcgtagc gactcatttt tgtcatcaag
    35881 attcacccct tacaaatata gataaagtct gactttgtgc gcccccagaa aattggcgct
    35941 gccgtacagc gtgaccgccg aatgtgcggg aatggtaacg ctgcgtggcc tttccagagg
    36001 atgcatctcc agccctctgg cgtcatacca gtaaaaacga taatgaacgg taacgggttc
    36061 ttgcctttcg ttataaagcg ttgaggatgc tgaaggttga atatcagacg tcgaaaggac
    36121 gggcttttct gcactgatgc ccgcagccaa taaagatgac tccatcacca gcgattgctc
    36181 atcattcacc ggaatttccg gatgtgtacg acagcccacc agcactaaca acgccagaga
    36241 caccagccca aagcatcctt ttctcatcgt tacagacctt tatgcgccag cattggtccc
    36301 agcggacggc cacccaacaa gtgcatatgg atgtggtaaa cctcttgtcc gccgtggcgg
    36361 ttggtgttca tgatcagacg atagccatct tcggcaatac cttcttgctc agcaattttt
    36421 gccgctacgg tgatcatgcg tcccagcgcc tgctcatgct cagcagacac gtcgttcaca
    36481 gtcggaatga ggatattcgg aatgatcaga atatgcgttg gcgcttgcgg cgaaatatcg
    36541 cgaaacgccg ttaccagatc atcctggtag acgatatcgg aggggatctc acgacgaata
    36601 attttgctga atatagtttc ttctgccacg acattttcct ttttcaaata gccatgcgtt
    36661 gcgccatgct acgccgcgcc acactgcgag tatagagtat ggtcgagtta aacctgctct
    36721 ttcaacctta actcacgatt tcttaagcaa aaaatcgttt tgctgccgta tatatcgcca
    36781 ttattcccat ttctgcctgc gaatgcgctg aaaagacatt ctctgtttgg tttacacact
    36841 aaatatgaat gcgtatattt ctcatttgca tttacataca aaattattcg cacactaaat
    36901 ataaccgctc atcaccctgc tccggcatga gcctgacgcc aacataaacc aagagatttc
    36961 aaatgctttc gacacaattt aacagggata atcaacatca agctatcatc aaaccgtcac
    37021 tccttgccgg ttgcatagca ctggcactat taccttccgc cgcttttgct gcaccagtca
    37081 ctgaagaaac ggtgattgtt gagggttcag ccacagcccc agatgatggc gaaaatgatt
    37141 acaacgtaac gtctacctct gcgggtacaa aaatgcagat gactcaacgt gatattcctc
    37201 agtcggtcac tattgttagc cagcagcgga tggaagatca gcagttacaa acgctgggcg
    37261 aagtgatgga aaacacgctg gggatcagca aaagtcaggc ggattccgat cgtgctcttt
    37321 attattcccg cggattccag atcgataact atatggttga tggtatcccc acctattttg
    37381 aatcgcgctg gaatctgggc gacgcacttt ctgatatggc actgtttgaa cgcgtagaag
    37441 tagtgcgtgg cgcgacaggc ctcatgaccg ggacgggtaa tccatctgcg gcaattaata
    37501 tggttcgaaa acacgcgacc agtcgtgaat ttaaaggcga tgtctcggcg gaatacggta
    37561 gctggaacaa agaacggtat gtggcggatt tacaaagccc actcaccgaa gatggtaaaa
    37621 tccgcgcacg aattgtcggc ggctaccaga ataacgactc atggctggac cgctacaaca
    37681 gtgaaaagac cttcttctcc ggcattgtcg atgctgattt aggcgatctt acgatgcttt
    37741 cagccggtta cgaatatcag cgcattgatg ttaatagccc aacctggggc ggtttaccgc
    37801 gctggaatac tgatggcagc agcaacagtt acgatcgcgc acgcagtacc gcacctgact
    37861 gggcgtataa cgataaagag atcaacaagg tctttatgac cctcaagcag cggtttgctg
    37921 atacctggca agcgacactg aatgccaccc actccgaagt cgaatttgac agtaaaatga
    37981 tgtatgtcga tgcctatgta aacaaagcgg atggtatgct ggttgggcca tacagtaatt
    38041 atggacctgg ttttgattat gtcggcggca ccggttggaa cagcggcaaa cgtaaagttg
    38101 atgcgctgga tttgtttgct gacggtagtt atgaattgtt tggtcgtcag cacaatctaa
    38161 tgtttggtgg cagttacagc aaacaaaaca atcgttacat cagttcatgg gccaacatct
    38221 tcccggatga aattggcagt ttctacaact ttaatggcaa tttcccacaa accgactggt
    38281 caccacagag cctggcgcag gacgatacca cacatatgaa atcgttatat gctgccactc
    38341 gtgtcaccct tgccgatccg ctgcatctga tcctcggcgc tcgttatacc aactggcggg
    38401 ttgatacgct gacttacagc atggagaaaa accacaccac gccttatgct ggtctggtgt
    38461 ttgacatcaa tgacaactgg tcgacctacg ccagctatac ctctattttc cagccgcaaa
    38521 atgatcgtga cagttcaggc aaatatctgg ctccaatcac cggtaacaac tacgagctgg
    38581 gtctgaaatc ggactggatg aatagccgtc tgaccaccac gttagccatc ttccgtattg
    38641 agcaggataa tgtagctcag tccaccggta cacctatccc cggcagcaac ggcgaaaccg
    38701 cctataaagc ggtggatggg acagtcagta aaggtgtgga atttgaactc aacggcgcaa
    38761 ttaccgacaa ctggcagctg acgtttggcg caacacgcta tattgcagaa gataacgaag
    38821 gaaacgccgt taatcctaat ctgccacgct ccacggttaa aatgttcacc agctatcggt
    38881 tgcctgtcat gccagagttg acggtcggcg gtggtgttaa ctggcaaaat cgcgtgtata
    38941 ccgacaccgt gacaccgtat ggcaccttcc gcgccgagca aggtagctac gcgctggtgg
    39001 atctcttcac ccgctaccag gtgacgaaaa acttctcgtt acaggggaac gtcaataacc
    39061 tgttcgacaa aacctacgat accaacgtgg aaggttctat cgtctacggc gcaccgcgta
    39121 atttcagcat taccggcacg tatcaattct gaataacacc tgtaaaaaag gcagccatct
    39181 ggctgcctta gtctccccaa cgtcttacgg attagtggtt acggatgtac tcatccatct
    39241 cggttttcag gttatcggat ttagtaccga aaatcgcctg aacaccagaa ccagcaacca
    39301 ctacgcccgc tgcgcccagt ttcttcaggc cagcctgatc cactttagac acatcagcaa
    39361 cgctgacgcg cagacgggta atacatgcgt cgaggttagt aatgttttct ttaccaccaa
    39421 atgcagcaac cagagccggt gccatttcgc tggtacctgt cgcttttgca tcttcagtcg
    39481 catcttcacg acccggcgtt ttcagatcca gtgctttaat cagcacgcgg aagatggtgt
    39541 agtaaacaat cgcataaccg ataccgacga tcgggaacag ccacagtttg ctgctgttac
    39601 cagacagaac gatgaagtcg atcagaccgt gcgagaacga cgtaccgtca cgcatcccca
    39661 aaagaataca gattgggaat gccaggcctg ccagaatcgc gtggatgatg tacaggatcg
    39721 gcgcaacgaa catgaaggag aactcgatcg gctcggtgat accggtcagg aacgaggtca
    39781 gcgccgcgga gatcataata ccgcccactt tcgcgcggtt ttctggttta gcagagtgcc
    39841 agatagcaat tgcggcagct ggcagaccgt acattttgaa caggaagcca ccagacagtt
    39901 tacccgcagt cgggtcaccc gccatataac gcggaatgtc gccgtggaaa acctgacctg
    39961 ctgcgttagt gtattcacca atttgcatct ggaaaggtac gttccagatg tggtgcagac
    40021 caaacggtac caggcaacgt tcgatgaaac cgtaaatgcc aaacgcaact accgggttct
    40081 ggtaagcagc ccactgagag aaggtctgga ttgcagaacc aatcggcggc caaatgaagg
    40141 acagcacaac gccagtaaag atggcagcca ggccagaaat gatcggcaca aagcgtttac
    40201 cggcaaagaa gccaagatac tcaggcagct taatacggta gaaacggtta aacatatacg
    40261 ctgcaatcgc accggagata atccctccga gtacgccagt atccgccagg tgtttagagg
    40321 cgatttcttc agcaggtaaa tgcagtacca gtggcgcaac cacggccatg gttttaacca
    40381 tgatgccata ggcaacaact gcggccagcg cggatacgcc atcgttattg gtaaagccga
    40441 gggcgacacc gatcgcaaaa atcagtggca tgtttgcaaa gacggaaccg cctgcttctg
    40501 ccataacatg cgatacaacg gcgggcagcc agctgaaatt cgcggaaccg acgcccagca
    40561 gaatacctgc gataggcagt acggataccg gcagcatcag cgatttaccg accttttgca
    40621 ggttagcaaa tgcattctta aacataattg agagtgctcc tgagtatggg tgcttttttt
    40681 acgttctcac gcgtggcaag gggggagagc ctcgccgtgt acagggcatc taagcgccct
    40741 ttatttatta cacagagtaa aataattcag tgccgatttg tttgacggct atcacgtttc
    40801 aacttcagat cattggagaa gttgcacatt ttgacaaaac atatgtcaca atatttcaaa
    40861 cgtggttatt caccgcccaa ttttcggcgg tgaactttac tcgttttagc cattaattac
    40921 gagctttaaa aaaactcatt caacggatgg attgaaggcg ggaagcgtcg atgtgaaaca
    40981 gacgggcgaa gttatcggtg gttacctgcg ccagttcttc aacggcaaca cctttcaaca
    41041 cagccatgta ttctgcaacg tcacgaacca tcgcaggttg attctctttt cctcgatgcg
    41101 gtaccggcgc aaggtaaggt gagtcagttt ccaccagtaa ccgatccagg gggacataac
    41161 gcgcagcatc gcgcagttgc tccgcattac ggaaggtcac aatgccggaa aaggagatgt
    41221 aaaatccgag atccagtaat ttacccgccg tttctctgtc ctctgtaaaa cagtgtagta
    41281 cgccaccgca atccgtcact ttttcttcgc gcagaattgc cagcgtatcg gcgcgggcgt
    41341 cacgggtgtg gacgataacc ggcttgttca gttcacgacc aatctggata tgatggatga
    41401 aggactcttg ctgacgtact ttagtttcag gcgtgtaata ataatccagc ccggtttcac
    41461 ccagcgctac aacgccctct tctgccgcca gacgacgtaa atcttctaca tcgtagggat
    41521 cattctggtt gagtggatgc acgccacaag aaaatacgac gttgtcgcgt tcgcctacca
    41581 gatcccgcat gtgtaaataa ccaggtaatg ttgtggcgac tgccagacaa aatttcacat
    41641 cgcgtgcggc ggctttcgcc agaacgtcat ccacgtcctt atgcaaagat tcataatcca
    41701 gaccatcgag atggcagtgt gagtcgacta aaaacatgat gtctctctta aagatgagga
    41761 accggtagca caacgcccgg ttgcaggtaa tgctcaatac gcagtaaaag atcggtgatg
    41821 agaagctcgc ggttaatacc tgtgacagac attaactgtt cacgaatgtg gcaaacatcc
    41881 cccagtatag cctgcaggcg cgagggagat agatggtttg ccagttcgac gaccaggccc
    41941 ggcacatcaa cattggtcac ctgcgcagcg ccatgatggc gttttagcgc atccatcagc
    42001 aacgttgcca gccagtgtaa acgcgccgga gcttgttcat gattaagggc cgctagcagc
    42061 gaataccagt cgcccgatgg cacgctatat gccaacgcct gacacaatgt ttcacgagcc
    42121 tgccagttat ctccctgaaa caacgccagt gccgcgccag gcgaaccggc gcttaagcgc
    42181 aatgcggcaa gtaatgcatc ctgtgacatt gtcacttcgc gtgaaagcca ggtcacggcg
    42241 tactgttccg gcggcggcgc aaggtaatgt aaccgacaac gactacgtaa tgttgccagt
    42301 aaacgttcag gctcgcgggt agccaggaaa aaccaggttt ctgctggtgg ctcttcaagc
    42361 gttttcagca atgcgttagc cgcggcgtcg gtcagtaagg cagcatcggt tacccagaca
    42421 actttcgcac cacctaaacg tgcgtgctca tttaactttt cggtgacttc acgtaccgca
    42481 tcaatgccca gcgcattttt ccctttctcg ggagccaggg tgtaataatc gggatgcgta
    42541 ccagcctgca tcaactgaca tccacgacag tgaccgcaac ttttgtggcc ctgcggttgt
    42601 tggcagagta aataacggct cagggcgtag attaaagcat cctcgcccat acccggtaac
    42661 gcctgaatga gtagcgcatg gtgacctctt ccggcctgat agctggctac cagtttttcg
    42721 aaatcaggtc gtaaccatgg ataccatctc atgcgtccaa ctccttcacc caattggtca
    42781 cggtagtgcg gattgcatcc atcacggact ccagcggctg ggtggcatca atggtatgaa
    42841 tgcttttatc ttgtgctgcc agttccagat agcgggcgcg ggtgcgatta aagaaatcga
    42901 aagactcttg ctcaatacga tccagctcgc cgcgagcacg cgcacgtttt aagccaactt
    42961 ccggggtaac atcgagatag agcgttaagt cggggcgaaa atccccgaga acagcatcac
    43021 gcaatgttgc cagcatatgt tggtcaatac cacgtccgcc gccctgatac gcctgagtgg
    43081 agagatcgtg gcgatcgcca atcacccaag tgccgttagc cagcgctggt ttgatgaccg
    43141 tttctaccag ttgaacgcgc gcggcataaa acatcagaac ttcggcttta tcggtaatga
    43201 cttcatcgcc taccgatttg atatccagca ccaggcttct taacttttcg gcaagttgcg
    43261 taccgccagg ttcccgagtg aaaaccatgt cgcggatacc cagttgctcg agcgtctcaa
    43321 ccaccacgtt acgcgcggta gttttgcctg cgccttccag cccctcaatg acgatatact
    43381 tactgcgcat ttttttcctt aagcactttc agataatcct gcacagactt gttatgactg
    43441 gcaagattgg tattaaacgt gtgaccacct ttaccatcgg ccacaaaata gagatacggc
    43501 gtttttgccg gatgcgcagc agccttcagc gaatccgccc ccggcgtagc tattgcacct
    43561 ggcggcaaac cggtaatggt ataggtgtta tacgctgtcg gcgtttccag gtctgcacga
    43621 gaaagtttgc cattataacg ctctcccatc ccgtaaatca cggtcgggtc ggtctgcagg
    43681 cgcataccaa tgcgtaaccg gttgataaat accgaggcaa cctgatcgcg ttcactggca
    43741 acggcggttt ctttttcgat aattgatgcc atcgtcacca gctggttttt atctttatag
    43801 ggcagaccgt ccgcacgccc ttcccaggcg ctatcgaccg ctttcaccat tttcttgtgc
    43861 gctcgcttga gtaacgcgac atcggtggta ttggcggtat acatccaggt gtctggccag
    43921 aaccaacctt caatccactc tgggttttcc agttcaagtg cctgcgctac ggtggcgtac
    43981 ttatcgtcgc tcagcgtatg cttgatatac ggggcctcac gcaattgctt gaggtaatcg
    44041 ctcagacgca tcccttctac cagtcgcaga gggaactgtg cttctttacc gctttccagc
    44101 aatttcagca tctcgcgcac ggtcatctgc ggtgtaaagc ggtaagtccc ggctttaaag
    44161 tgagaaagat ccggttcgat acgcagcagc cattgaaaaa cccgtgggcg attgatgatc
    44221 ttatcggcat aaagctgttc acctagcgcc agacgtccgg tccctggctt cagggtaaat
    44281 atcgtctctt ctttgataag caatttgctg tcggcaagat ggcgaacctt ccagacgccc
    44341 acaccagcgg cgatacccag taccaccagc aataacaaga taatcaataa cacttttttc
    44401 atgactaatt cgggcgctca caaagtgggg ctaaatattc atataacgtt gctgacgaaa
    44461 aggagacatc gccacaggca cgtacgggca tcactggcat taacgcatta caaataacca
    44521 tctcatctgc ctgcaacgcc tcctccagcg aggcttgcac ttcgacaagc tgataagagg
    44581 attgtgccag taaacggata cagaattgtc gcataatgcc gttaacacct gcctgatcca
    44641 gtcgcggcgt ataaactacg ttgcccttcc gccagaacaa attagccgca cagcattccg
    44701 taacccaccc ttcgctgtca aggaccagcg cctcatcagc gtttgtctgc tcaagatgag
    44761 agcggatcaa tacttgctca agccgattaa gatgtttaat acctgcaaga tgaggattgc
    44821 gccccagccg caccgggctt agcgccaacg tcatcccctc gttacgcaaa cggtcgtaat
    44881 gtgcgggata aaccgtaacg gagagaatcc gcgttgccgg tccgctgttc aatgtgctgt
    44941 atcctcgccc gccactaccg cgactgatca ccactttcag cacaccattt tgctgttctg
    45001 ctgccagcgt tttcatctct agttcaagct gaggccagaa gtcacaggaa atcatcaacc
    45061 gctgacaagc atcctgtagt cgctggatat gcgccgataa caaactgact ttaccgtcga
    45121 taactctggc ggtggtaaaa caaccatcac caaactgcgt tgcccgatcg cttactgcca
    45181 gcgattcctg cttatgaccg ttaattaaga acataccggc tccttatcag agaattgtta
    45241 gtgtggcagc atgttcacta cggaacaagt cggaataaaa gctaagaaaa aaggcccgca
    45301 agcggacctt ttataagggt gggaaatgac aacttagatc tttttaaaga tcaaagaacc
    45361 attagtgcca ccgaagccga aggagttaca cagcgtgtat tccattccgc ttacctggcg
    45421 cgcttcgtgc ggtacgaaat ccagatcgca accttcatcc gggttatcca ggttgatggt
    45481 tggcggaaca gcctgatcgc gcagcgccag gatggagtag atagattcta ctgcacccgc
    45541 cgcacctaac aggtgaccgg tcatagattt cgtggagctt accaacacac ggcttgcagc
    45601 ttcaccgaag atggttttca ccgcctgcgc ttcagcttta tcgccagccg gcgtagaagt
    45661 accgtgcgcg ttaacgtagc caatctgact cgcttcaatg cctgcatcac gcagagcatt
    45721 tgccatcgcc agagctgcgc ctgcgccatt ttctggcggt gacgtcatat gataagcatc
    45781 gctgctcata ccaaagccga cgagttcagc gtaaattttc gcaccgcgtt ttttcgcgtg
    45841 ttcgtactct tcaagtacca gcataccggc accatcgccc agtacgaaac catcacgctc
    45901 tttatcccac gggcggctcg ccgcttgcgg gttatcattg cgggtagata atgcacgtgc
    45961 cgcgccaaaa ccaccaacgc ccagcggcgt actggctttc tctgcgccac ctgcaaccat
    46021 cacgtcagca tcgccatacg cgataatacg cgcagcatgg ccaatgttgt gcacgccgga
    46081 agtacaggcg gtcgcgatag agatgcttgg gccacgcagg ccatacatga tagtcagatg
    46141 acctgccacc atgttcacaa tcgttgacgg aacgaagaat gggctgatct tacgtggacc
    46201 accgttcatc agagatgtgt ggttttcttc gatcagtccg aggccgccaa tcccggagcc
    46261 aattgcggca ccaatgcggg ttgcgttctc ttccgttatt tcaaggccag aatcctgcat
    46321 ggcctgaacg ccagcgacaa ttccatattg aatgaaggca tccatcttgc gctgttcttt
    46381 gcgcgagata atgtcctcac agttaaaatc ctttactaag ccagcaaatt tcgttgcata
    46441 ggcgctagta tcgaaatggt cgattaggct gatgccactc tgaccggcaa gcagagcttt
    46501 ccaggtagac tctacggtat tgccgacagg agacaacatg cccagtccgg tcacaactac
    46561 acgacgctta gacacgtttg tcctccaggg agggaaaaaa tgattctagt gggacaaaaa
    46621 gataaaactc aggcggtcga acgaccgcct ggagatgttc acttacgcct ggtggccgtt
    46681 gatgtaatca atggcagcct gaacggtggt gattttctca gcttcttcgt ccggaatctc
    46741 agtatcaaac tcttcttcca gagccattac cagctcaacg gtgtcaagag aatccgcgcc
    46801 caggtcttca acgaaagaag cattgttggt aacttcttcc tgcttaacgc ccagctgttc
    46861 gccgataatt ttcttaacgc gttcttcgat agtgctcata ctcttaaatt tcctatcaaa
    46921 actcgctttc gcgatggttt tcgtagtgta taaaatgttg aaaaatttgc aactaaatcc
    46981 cggcaggtct taccacgatt ttacgttatt ttgaggcctt accccccaat aacgcaaatc
    47041 attttgcact aattattact cataaccacg cagactgcgc gcaacatgag cattttgtgc
    47101 aaatcgcggt cagaccatgt acatcccgcc gttcacatgc aaagtttcac ccgtgatgta
    47161 agctgcttcg tcggatgcca ggaatgcaac cgcgttggcg atttcctgtg cgccgccgag
    47221 gcgacccgca ggaacctgcg ccaggatacc cgcacgctgg tcatcgctca gcgcacgtgt
    47281 catgtccgtt tcaataaagc ccggagcaac aacgtttaca gtaataccgc gtgacgcaac
    47341 ttcgcgcgcc agtgatttac tgaagccgat caagcccgct ttcgccgcag cgtagttggc
    47401 ctgaccgcca tttcccatgg taccaaccac agaaccgata gtgataatac gaccatgacg
    47461 ctttttcatc atagcgcgca ttaccgcttt tgacagacgg aaaacagatg aaaggttagt
    47521 ttcgataata tcgttccact cttcatcttt cattcgcatt aacaggttat cacgagtgat
    47581 accggcatta ttgaccagga tatccacttc accaaattct gcgcgaattt tttccagaac
    47641 agattcgata gatgccgggt cggtcacatt caacatcata cctttgccgt tggcacctaa
    47701 ataatcactg atcgcctgag cgccattttc actggtcgca gtgccaataa ctttcgcgcc
    47761 acgggctgcg agcgtttcag caattgcacg gccaattccg cggcttgcac cggttaccag
    47821 tgcgattttt ccttcaaaat tcatgatttt cctcttttaa agctcgagcg ccgctgccat
    47881 cgctgaaggt tcgttcagcg ccgaggcggt cagggtgtcg acaatgcgtt tcgtcaggcc
    47941 agtaagcact ttgcccgggc cgacttcata gagatgttct acgccttgcg ctgccatgta
    48001 ttcaacagac ttcgtccact gaaccgggtt atacaactga cgtaccagtg cgtcacggat
    48061 ggcatcacca ttggtttcgc atttcacatc aacgttattc acaacaggaa ctgttggtgc
    48121 gttaaaggtg attttcgcta attctactgc cagtttgtcg gctgctggtt tcatcagcgc
    48181 acagtgagac ggtacgctca ctggtaacgg tagagcgcgt tttgcgcccg cagctttaca
    48241 ggcagcgcca gcacgctcaa ctgcttcttt atgaccggca ataaccacct gtcccggaga
    48301 gttaaagttt accggagaaa cgacctgacc ttctgcagct tcttcacacg ctttcgcaat
    48361 agacgcatca tccagaccga tgattgccgc catagcgccc gttccttccg gtacggcttc
    48421 ttgcataaac ttaccgcgca tctcaaccag acgcaccgca tcagcgaaat caatcacgcc
    48481 agcgcatacc agcgcggagt attcccccag gctgtgaccg gccatcattg ccggtgcttt
    48541 accgccctgc tgctgccata cgcgatacag cgcaacagat gcagtcaaca gcgctggctg
    48601 ggtttgccag gttttattca gttcttcagc tggcccctgc tgggtcagcg cccacaggtc
    48661 gtagcccagc gccgcagaag cttcagcaaa cgtttcttcg acaattggat agctcgccgc
    48721 catatcagcc agcattccaa cggtttgaga accctgtcca gggaacacaa atgcaaattg
    48781 cgtcatgttt taatccttat cctagaaacg aaccagcgcg gagccccagg tgaatccacc
    48841 gccaaaggct tcaagcagaa ccaactgccc cggcttaatg cgcccgtcgc gtacagcttc
    48901 atccagagcg cacgggacag aggccgcaga ggtattaccg tggcgatcca gcgtcaccac
    48961 gacattgtcc atcgacatac cgagtttttt cgccgttgca ctgataatac gcaggttagc
    49021 ctgatgcgga accagccagt ccagttgaga acggtcaaga ttattcgccg ccagcgtctc
    49081 atcaacgatg tgcgccagtt ctgttaccgc aaccttgaag acttcgttgc ccgccatcgt
    49141 cagatgaatt gaattctctg gattcacacg gtcagcatta ggcagcgtca gcaactcacc
    49201 atagctaccg tcggcatgca gatgggtgga gatgattccc ggctcttcag aggcagccag
    49261 caccgcagcg cccgcgccat cgccaaaaat aataatagtc ccacgatcgg ttggatcgca
    49321 ggtgcgcgcc agtacatcgg aaccgacgac cagagcatac ttcaccgccc cagatttcac
    49381 gtattgatcg gctacgctta atgcataggt gaaacctgcg caggctgctg caacgtcaaa
    49441 tgccgggcaa cctttaatgc ccagcatgct ttgaatctga caagctgcgc tcgggaaagc
    49501 gtgcgtcgca gaagtcgttg ccacaacgat caggccaatc tggtctttct caatacccgc
    49561 catctcaatt gcgcgtgtcg ccgcttcaaa gcccatggtt gaaacggttt cgtttggcgc
    49621 ggcaatgtgg cgttcgcgga taccggtacg agtgacaatc cactcgtcag aggtgtccac
    49681 cattttttcc aaatcggcgt ttgtccgcac ttgttcgggc agatagctgc cagtaccaat
    49741 aatcttcgta tacatgtacg ctcagtcact tttcggttat ataccgtcac ttgcaaactg
    49801 cgagttcgct ggcagcgtcc tgctaccgca gagttccgct tttgccaccg tccagcagct
    49861 caaaaccagc tgggtataca gattccaggc gagcggcaat tcgctgagga acttgtcgct
    49921 gcaccgcctg cactgcctgt tcaatcgcga ccgcaaaagc tcgctgattg gctgcaccat
    49981 gactttttat caccgtgccg cgcaatccta acagacaggc gccgttatac tggtcggggt
    50041 tgaggtgact gaatcgcctc gtcaggctct tttgtagcca acgctttaat aacagtagcc
    50101 accacgaccg ttttttccct tcaccctgag atttcagcag agaaaggaac atcctgacaa
    50161 caccttccat cgtctttaat gtgacatttc ctgtaaagcc gtcacaaacc agcacatctg
    50221 tcttgccagt taacaactca ttggcttcaa gatagccgat ataattgata gaagggattg
    50281 ttttaagcac cgctgaggca tcccgaatac tgtcgagacc ctttacttct tcttcaccaa
    50341 tattgagcaa cgccacgcga ggattaggaa tttccaccac ctcttcagcc agaactgagc
    50401 ccataatggc aaattgcacc aacattgtac tgtcacaatc gacgttggcc cctaaatcga
    50461 ggaccaccgt tttgcccttt tgctgatgcg gtaataccgt caccagcgcc ggacgctcaa
    50521 tcccctccag gggcttgagt aataattttg ccagccccat cagcgccccg gtattaccgg
    50581 cactgacaca ggcttgcgct cgaccttctt tcaccagctc cagggccacg cgcattgaac
    50641 tcccacgact ggcgcggata gcttgcgaag gccgggcatc actggcgata actgactgcg
    50701 caggaataat ctgcagacgc gaacgttgtt caaagtcagc tttagcaagt aatggcgtga
    50761 tggcgtcggg attgccgact aaaagaagag tgagttgcga attagaattc agtgcctgca
    50821 atgctgcagg cactgtcacg gaagggccaa aatcccctcc catgacatct aacgccaggg
    50881 ttagacgtgt caaggtatcg tcgccgcccg gtttggtctt tccccagttg cctggggaaa
    50941 atcctcacta agcttcacca cgcagacgcg tgattactta gcgatgacct tgcggccgcg
    51001 gtagtaaccg tcggcagtga tgtggtgacg caggtgtttt tcaccagaag ttttgtctac
    51061 agacaggctg gtgactgcgg tcagcgcgtc atgggaacga cgcatgccac gtttggaacg
    51121 ggttggttta ttctgttgta cggccatgga ccttactcct caattacggt ttatccccga
    51181 tccaacgggg agcaccaatt acttacgctt taagctggct aatacggcaa atgggtttgg
    51241 cttttgcgct tcttcaggca gttcaccaaa gaccatgtcc gcttcggaca cttcacagtg
    51301 ttcagaatca tgcaccggaa ctaccggcaa ggcgaggatg atttcatctt caaccattgc
    51361 aagcagatcg atttcaccga attcgttaac ctcaatcggt tcatacgctt ccggcagtgc
    51421 ttcagcctgt tcgtctgaac gcacaggact aaaacaatac gttgtgtaga cctgatgagt
    51481 aaacggcttc ccgcaacgct gacactcgag cgttaccgtc accttcgcat cgccgtttaa
    51541 cactgcgaga cgttggttat cgatagcgaa cgacatggag cattccacat cactgtccac
    51601 actgactacg gattcggcga cgcgctcaac ctgatcagga gtatagatac cctggtaatc
    51661 aaggcgtttt tgagccgtac gaaccggatc gagagtcagg ggtaatttta ccttttgcat
    51721 agggcgcgca tattaacttt gtaacgtcat agagtcaaag aaaaaggcag cctgtggttg
    51781 ccttttgcca ataattcgca cacattgcgg gttactgctt tattttcgtt cagtgctgat
    51841 aacgaacatc aacctgcaaa acgaagcgca tagtttaaaa tggctatcat caatacgcta
    51901 tatctgatgg aaaaaaatat gcctaaactt attttagcct ccacttcgcc ctggcgtcgc
    51961 gctcttctgg aaaaactgca aatctctttt gaatgtgcag caccagaggt cgacgaaacc
    52021 ccacgcagcg acgaatcacc gcgacagttg gtgcttcgac tggcacaaga aaaagcgcaa
    52081 tctctggcgt cacgttatcc ggatcattta attattggtt cagaccaggt atgtgttctt
    52141 gatggcgaaa tcaccggtaa accgttaacg gaagaaaatg cccgtctgca attacgcaaa
    52201 gccagcggca atatcgtcac cttctatact ggactggcgt tgtttaattc ggcgaatggg
    52261 catctgcaaa cagaagtgga gccttttgac gtccatttcc gtcacctgag cgaggcggag
    52321 attgataatt acgtgcgtaa ggagcatccc ctgcactgcg cgggtagctt taagagtgaa
    52381 ggatttggca ttacgctgtt tgagcgttta gaggggcgag atcctaacac gctggttggt
    52441 ttaccgctaa tcgcgctgtg tcagatgtta cgtcgggaag ggaaaaaccc gctgatggga
    52501 tagttgtttg cgccggatgc ggttacgtcg catccggcaa tcggtgctgg cggcctgatg
    52561 cggcgtaaac gccttatcag gccaaccgcc cattatcagg tttatatgct tgtattagcg
    52621 cgccttacgc agcttttgca aacaacgctt caaaccttca tccatcggcg cttcgatacg
    52681 catcacctct ccggtccccg gatgggtaaa tttcaacgct gcggcgtgca ggaacagacg
    52741 atttaatccc gtgccggctt cagtgagctg tctgtcaaat tcacggtcac cgtagcgatc
    52801 gtcaaaggca atcggatgac ccgcatattg tgtatgcaca cggatctgat gagtacgccc
    52861 tgttaccggg ctacaacgca ccagggtggc aaatgcatag cgttcttcca ctttaaagcg
    52921 tgtttccgac ggtttgcctt cctgactcac acgcacaata cgttcgccgc tttgcagaat
    52981 atttttcaat aacggcgctt gaacgctctt cacatgcgac tgccactgac cgcgcaccag
    53041 cgccaggtaa tctttttgca tccctttttc acgtaattgc tcatgcagag aacgcaacgc
    53101 cgagcgtttt ttcgctacca gcaacacacc tgaagtgtcc cggtcgagac gatgaaccag
    53161 ttcaaggaac cgcgcttccg ggcgcaacgc ccgcaaacct tcgataacgc cgaagcttaa
    53221 accactgccg ccatgtaccg ccgtaccgga aggtttattc agcaccagga tatggtcatc
    53281 ttcatataag atgacgtccg ccagcgctgc caccttttgc agatgtggcg aaaccgcctc
    53341 ttcttcccgt tcagcaacgc gaaccggtgg gatgcgtacc tcatcacccg cttcgagttt
    53401 atattcaggc ttaatacgtt ttttgttcac ccgcacttcg cctttacgca aaatacggta
    53461 aatcatactt tttggtacac ctttcaattg ggtacgcaaa aagttatcga tacgttgccc
    53521 cgcttcgtca gcggtgatag caacaatttt tacggatgga gtctctgttt tcatggtggg
    53581 cgattctaat tagccaacag gattcgcgcc actcattttt ctatgcttat atttagtttt
    53641 gcaccttatt acttcactac gtgatcactt tattgatggt tattaaacca atcaccagca
    53701 agaagtgaaa aaactgtgag taagcaggtg ataaatggta aaagtcatct tgctataaca
    53761 aggcttgcag tggaataatg aggccgtttc cgtgtccatc cttgttaaaa caagaaattt
    53821 tacggaataa cccattttgc ccgaccgatc atccacgcag caatggcgta agacgtattg
    53881 atctttcagg cagttagcgg gctgcgggtt gcagtcctta ccggtagatg gaaatatttc
    53941 tggagagtaa tacccagtct gtttctttga taattgcgct gtttttccgc atgaaaaacg
    54001 ggcaaccgac actctgcgcc tctttgagct gacgataacc gtgaggttgg cgacgcgact
    54061 agacacgagg ccatcggttc acacccggaa aggcgttact ttgcccgcag cttagtcgtc
    54121 aatgtaagaa taatgagtaa gttacgatga aaagaatgtt aatcaacgca actcagcagg
    54181 aagagttgcg cgttgccctt gtagatgggc agcgtctgta tgacctggat atcgaaagtc
    54241 cagggcacga gcagaaaaag gcaaacatct acaaaggtaa aatcacccgc attgaaccga
    54301 gtctggaagc tgcttttgtt gattacggcg ctgaacgtca cggtttcctc ccactaaaag
    54361 aaattgcccg cgaatatttc cctgctaact acagtgctca tggtcgtccc aacattaaag
    54421 atgtgttgcg tgaaggtcag gaagtcattg ttcagatcga taaagaagag cgcggcaaca
    54481 aaggcgcggc attaaccacc tttatcagtc tggcgggtag ctatctggtt ctgatgccga
    54541 acaacccgcg cgcgggtggc atttctcgtc gtatcgaagg cgacgaccgt accgaattaa
    54601 aagaagcact ggcaagcctt gaactgccgg aaggcatggg gcttatcgtg cgcaccgctg
    54661 gcgtcggcaa atctgctgag gcgctgcaat gggatttaag cttccgtctg aaacactggg
    54721 aagccatcaa aaaagccgct gaaagccgcc cggctccgtt cctgattcat caggagagca
    54781 acgtaatcgt tcgcgcattc cgcgattact tacgtcagga catcggcgaa atccttatcg
    54841 ataacccgaa agtgctcgaa ctggcacgcc agcatatcgc tgcattaggt cgcccggatt
    54901 tcagcagcaa aatcaaactg tacaccggcg agatcccgct gttcagccac taccagatcg
    54961 agtcacagat tgagtccgcc ttccagcgtg aagttcgtct gccatccggt ggttccattg
    55021 ttatcgacag caccgaagcg ttaaccgcca tcgacatcaa ctccgcacgc gcgacccgcg
    55081 gcggcgatat cgaagaaacc gcgtttaaca ccaacctcga agctgccgat gagattgctc
    55141 gtcagctgcg cctgcgtgac ctcggcggcc tgattgttat cgacttcatc gacatgacgc
    55201 cagtacgcca ccagcgtgcg gtagaaaacc gtctgcgtga agcggtgcgt caggaccgtg
    55261 cgcgtattca aatcagccat atttctcgct ttggcctgct ggaaatgtcc cgtcagcgcc
    55321 tgagcccatc actgggtgaa tccagccatc acgtctgccc gcgctgctcc ggtaccggta
    55381 ccgtgcgtga caacgaatcg ctgtcgctct ctattctgcg tctgatcgaa gaagaagcgc
    55441 tgaaagagaa cacccaggaa gttcacgcca ttgttcctgt gccaatcgcg tcttatctgc
    55501 tgaatgaaaa acgttctgca gtgaatgcga ttgaaactcg tcaggacggc gtgcgctgtg
    55561 tgattgtgcc aaacgatcag atggaaaccc cgcactacca tgtgctgcgc gtgcgtaaag
    55621 gggaagaaac tccaacctta agctacatgc tgccgaagct gcatgaagaa gcgatggcgc
    55681 tgccgtctga agaagagttc gctgaacgta agcgtccgga acaacctgcg ctggctacct
    55741 ttgccatgcc ggatgtgccg ccagcgccaa cgccagctga acctgccgcg cctgtcgtag
    55801 ccccagcacc taaagctgca ccggcaacac cagcagctcc tgcacaacct gggttgttga
    55861 gccgcttctt cggcgcactg aaagcgctgt tcagcggtgg tgaagaaacc aaaccggccg
    55921 agcaaccagc accgaaagca gaagcgaaac cggaacgtca acaggatcgt cgcaagcctc
    55981 gtcagaacaa ccgccgtgac cgtaatgagc gccgcgactc ccgtagtgaa cgtacagaag
    56041 gcagcgataa tcgcgaagaa aaccgtcgta atcgtcgcca ggcacagcag caaactgccg
    56101 agacgcgtga gagccgtcag caggctgagg taacggaaaa agcgcgtacc accgacgagc
    56161 agcaagcgcc gcgtcgtgaa cgtagccgcc gccgtaacga tgataaacgt caggcgcaac
    56221 aagaagcgaa ggcgctgaat gttgaagagc aatctgttca ggaaaccgaa caggaagaac
    56281 gtgtacgtcc ggttcagccg cgtcgtaaac agcgtcagct caatcagaaa gtgcgttacg
    56341 agcaaagcgt agccgaagaa gcggtagtcg caccggtggt tgaagaaact gtcgttgccg
    56401 aaccaattgt tcaggaagcg ccagctccac gcacagaact ggtgaaagtc ccgctgccag
    56461 tcgtagcgca agctgcacca gaacagcaag aagagaacaa tgccgataac cgtgacaacg
    56521 gtggcatgcc gcgtcgttct cgccgctcgc ctcgtcacct gcgcgtgagt ggtcagcgtc
    56581 gtcgtcgcta tcgtgacgag cgttatccaa cccaatcgcc aatgccgttg accgtagcgt
    56641 gcgcatctcc ggaactggcc tctggcaaag tctggatccg ctatccaatt gtacgtccgc
    56701 aagatgtaca ggtcgaagag cagcgcgaac aggaagaagt acaagtgcag ccgatggtga
    56761 ctgaggtccc tgtcgccgcc gctgtcgaac cggttgttag cgcaccggtt gttgaagaag
    56821 tggctgaagt cgtagaagcc cccgttcagg ttgccgaacc gcaaccggaa atggctgaaa
    56881 cgacgcatcc tgaagtaatt gccgccgcgg taactgaaca gccgcaggtg attaccgagt
    56941 ctgatgttgc cgtagcccag gaagttgcag aacacgcaga accggtagtt gaaccgcagg
    57001 aagagacggc tgatattgaa gaagttgccg aaactgctga ggttgtggtt gctgaacctg
    57061 aagttgttgc tcaacctgcc gcaccagtcg cagcagaagt tgaaacggta gccgcggttg
    57121 aaccagagat caccgttgag cataaccacg ctaccgcgcc aatgacgcgc gctccggcac
    57181 cggaatatgt tccggaggca ccgcgtcaca gtgactggca gcgccctact tttgccttcg
    57241 aaggcaaagg tgccgcaggt ggtcatacgg caacgcatca tgcctctgcc gctcctgcgc
    57301 gtccgcaacc tgttgagtaa taattagctc aagcaatcaa gccctggtaa ctgccagggc
    57361 ttttttattt caggggtagc atctttgctg taatgacatt agcgttacat gtgctgtata
    57421 attatcatcc acgcaaagcc gaaggatata tttatggcag cagccaataa cattccagcc
    57481 aggcgcgaat ctttaaactt gcgcataaaa cccgcagaac gcgatcttat agaccgggcc
    57541 gctaaagccc gaggaaaaaa tcgctccgaa tttgtccttg aggccgccag agccgcagct
    57601 gaagaggcgc tcattgagca gagaattttc aggatcgatt ctgatgatta ccagctattt
    57661 ttgaatcgtc tggatcagcc ccccgcgccc aatgctgcat tacgcaaaac catgcaaaca
    57721 cccgcgccgt gggagcaaaa aaaatgattc aggcccccga gccactcatg gcaaggcatc
    57781 aattcacctc tttttgctcg ggagtagaaa cgatggataa ctggctaaag cagagagccc
    57841 taaaaaatca gcttgccggc gcatcacgta catttgttag ctgtgatacg tatagcaacg
    57901 ttttggcata ttattcgctt gcttccagcg ccgttgaaac gtatgtcgcg acaggacgat
    57961 ttcgccgaaa tatgccagaa ccgatccctg ttgtagtact tggtcgtctg gcaatagata
    58021 aatcattaca gggtcagggc atcggtcgtg cgatggtcag agatgccggt ctacgagtac
    58081 tacaggcggc tgaagtcatt ggtattcgcg gaatgttggt ccatgcgtta tcagaccagg
    58141 cccgtgagtt ttatctgcga gtggggtttg aaccatcgcc tgtcgattct atgatactga
    58201 tggcaacatt ggctgatttg caggaatgtc ttaaatagtt cgttatgtct catgcaaaaa
    58261 aatgcccgcc ccggcgatcc cagagcaggc agacaaaaca tacccagttt catgatatgt
    58321 tttaaagcga aattatttgt tgagctggaa gagcgacaat ccctgcatat cggtaaatgc
    58381 tttatacgac gcctgcaatg ccgtttgctg catgatgtaa gatgaaatag ttgcattcca
    58441 gtccacatca accagatcgc tcatctgctg cgtttgccct aaagcgcgat cgctacctaa
    58501 tgaatccagc gactccagtt cgttcagctg cgtgcctaat tccgcgcgaa cagtcagcac
    58561 attgttcagc gagtttttca gtccgcggtt ggttttatcc agtgccgcag cggcggtttc
    58621 tttatccgct tcgctatccg cgaccggcgt tttcagggct gcgatggcgc tatccagcat
    58681 ggcaaaaaga ttggtttcag aagcgctacc gtctggttcc gctaccgcgt tgctggtaat
    58741 actgtcgaaa attttgtcac ccgtgtgccc tatcaccatc gaacgcgaag catcgacctg
    58801 ttgtttaata ctttctgctc cgccttcgta tttgccatcc tcctcgctaa acggtgcgga
    58861 ttctgtttta taaccggcaa aaatgtagcg cccgttaccg tcagtggtgt tcgccagatt
    58921 cagcaactgg tcacgaagcc cctgaatatc cgtagccagc gaggcccggt catcgtcact
    58981 caaggtgcca ttgctggcgt agacaatttt ttcctgagca ttctggatag cggtggtgac
    59041 ctggctaagt acactctctt ccagtgacac tttttgagtg gcgaaagtac gcgccagcgt
    59101 gtactggctg ttttgcgcct gtgcctggga gagaacaaca gcttgtgatg cagcaatggg
    59161 atcatctgaa gggttaacga ctcgcttacc cgtcgacatc tgttcaccgt acttcatcca
    59221 ttctgcctga gaattggtga tgccgcgcat gttttgctgg tacatcatct gggtactgaa
    59281 acgcatttta tctcccctta gcgaatgtta atcagcgcat caaaaatcgc gtttgccgtc
    59341 tgcagaacct gcgcattcgc gaggtaatac tgctgaaaac gttgcagatt tccgtactcc
    59401 tcatcgagat tgacaccgga aatcgactgc tgctgattgg aaagctgcgt caccacatta
    59461 ccttgcgtgg cgctactggt tttcaacgtc gcggttttat taccgatatc actcactaac
    59521 gaggcataag cgtcgttaaa ggatttcgca ccgcccaccg ttttactgtt gctttgcaga
    59581 tccagcaggg cctgaccgtt gcggttgtcg ctatcacccg catcttctgc gctcgccatg
    59641 gcgattttcg cttcgtcagt gattaataca tccatgttga cgatggcgtc acttaccggt
    59701 ttcaacgtga agctgtcgtt aacggcaggc gttcctgtaa acgtcaactc cagaccatca
    59761 aatgccactt taccgttggc atccggcgtc accgtaaaag tggtattgct ggcaaggcgg
    59821 gtgacctgcc actgattatt atcgaacgag attttgtaat ctgtcgccag taccgcggag
    59881 gcatcagtta ccgttgcacc gatcgcaacg tcacctttgt ttttcgtgtt ttgcagaacc
    59941 gcgggcttac cgatagcaaa gaaatcttca ccggcatcgc cgttagcatc aaatccggct
    60001 ttgtgttggg tgttgaaagc ctcggcaaat gccagcgcca gttgtccaag cgtattacgc
    60061 gtctggtcca gatcctgaga acggaatgtc agaatgccgc ccagcgaccc ggtattcagc
    60121 aatttctccg ggatctcaat attgcctgcc gtcccatcaa tataagcgac agtcgtacga
    60181 gaagggtcgg cgctggaagg aactgccgcc agctgccgcg ccgtacttcc ctgaaccagt
    60241 gagtagccat tggccatcgt gatgttataa gtgccaccat cctgaacgct aacttctacg
    60301 ccaacaatct ggtttaattc actcaccagt tgatcgcgtt gatccagcag attgttaggt
    60361 gacgcccctg cccccacgcc tgtcagacgc gagatttgat cgttcaggct ggcgatttgt
    60421 ttagcgtaat tgttgatctg atcaacgctg gcacctatcg cgatattgac ctgtttgtcc
    60481 tggtcgcgca gatattgatc ggtggtttta aactgattca ccaacccttc tgatttccca
    60541 atcagcgcct ggcgcgctgc cgggtcttcc gcgttactca ccagcgtttg caggctggtg
    60601 aagaaatcct gcatctgtgt tgccagcgaa gaggtactgg tggagagcat attgtcgatt
    60661 ttcgacatct gctcatagcg ggcagtcagg ccgctacttt gcgtctgcgc agcacgtaac
    60721 tggttggtaa taaacgcatc atactcacgc tgcacaccag aaacgtagac gccattgcca
    60781 acccagccgc cagcgcccaa cgtgctattg gcctgcgcca taatagtggt ttggcgggta
    60841 tatccggcaa cgttatagct ggagatatta ttacttgccg tatttaacgc cgcctgggcc
    60901 gcgttcagtc cgctcatggc gttattgatc aagctggaca tggaggttcc ttataagcct
    60961 tcaattacag agtattatcg gcagcgaccc gccggacttg agttattcag aacagattat
    61021 caatgttcat gctgtaggtt ttgctcacct tgtcgcttat cgatttcatc tgctgaatca
    61081 tgctggtgag tttgcgggca tagtgaggat cggtggcata gcccgcgtcc tgtagggcct
    61141 gcgccccctg ctccgcactc gcggcggtcg tcacggcggc gtagcgcggg ttacgcgtta
    61201 acagcccaac gtaatccgac aatgcttcca gatacgagct gtagacccga aacttcgctt
    61261 ttactttctt cgcttcgcca ttttcatatt cagtcgtggt gatttcagtg actggccctt
    61321 tccagttgcc agaggctttg acgccaaaca ggttatagct cggctcgccg ttttcacggc
    61381 ggatttgccg ttgtccccag ccagattcca gcgccgcctg cgcgaggatc aaatgatgtg
    61441 gcacaccgct ttgctggctt gccagttggg cgggcaacga gagttgcgcg aggaatgctt
    61501 tactgtcacc cggcagcgaa tcatcgtagt tacgtggtac ggccttttgc accagctgcg
    61561 aaagcgtctg attttgataa cgcaccacgg tttcgagcgg gaatttcatc ggtgctgctg
    61621 gcgtggactc ctctggcaat ggttgttctg gcgtcatctg tttaaccatc atctctgcca
    61681 gccccagacc tttgcccgcc gtcatctgtt gggcaatctg ctggtcatac atactggtat
    61741 acaggcgagt gtgctcgctg ctgaacaggc catcttttgg taaagcgtcg cgcatgcttt
    61801 tcaacatcat ctgcacgaac atcccttcca cctggcgggc caccggacgg atatttgccg
    61861 ccggatcttc gcccgctttc gccttaagtt cgttgagcga ttgtgcatcc caggccgcac
    61921 ttgccagtag tttgctgtcg ctgatcatca gatgatttcc agttttgccc gcagacatcc
    61981 cgcactttgc attgattgca gtatggacat cagatccatc ggcgtagcgc ccagcgcatt
    62041 gagcgcacgc accacgttat tgaggctggc gctggaacgt acgctttgca gcgaaccgcc
    62101 gctctggcgt aaatcgatct gcgtttgtgg cgttaccacg gtctgcccgc caccaaacgg
    62161 tgtatctggc tggctgacat tggcctgacg attaactgtt actgagagat tcccctgcgc
    62221 taccgcgcag ctgtcgaggg tcacttcgcg attcatcacc accgaaccag tgcgcgagtt
    62281 aatcactact ttagcgtcct gcggggtaac attaacctgc atattctgga tatcggcaag
    62341 gaaacggacc tgggaactgt tgccactcgg tacgcgcacc tgaatagtcc gcgcatctaa
    62401 cgcggtggcg ctgccatatc cacgcacgcg gttgatggtg tcagcgattt gctgcgccat
    62461 actgaaatct tcttcgttaa gttgcaaatt aagggcattc ccgacgccaa actggctggg
    62521 caattcacgt tcaataaccg caccattggt gatccgtcca ccgttcagtt ggttcacctg
    62581 aacactgcta ccgccagcgg aggcccctgc gccgccaacc agaatattgc cctgtgccag
    62641 cgcatacacc tgactgtcaa cgcccttaag cggtgtcatc aataacgtac cgccacgcag
    62701 acttttggca tttcccatgg aagaaaccac cacgtcaatg gtttgcccct ggcgtccaaa
    62761 cggtggaagt gacgccgtca ccattaccgc agcgacgttt tttagctgca tattggtgcc
    62821 cgtcggaacg gtaattccca gctgtgagag catgttatta agcgtttgtg tggtaaacgg
    62881 cgtctgagtt gtctggtcac ctgtaccatc aagccccacc accaggccat agccaatcag
    62941 tgagttttgc cttaccccct gaacactggt gagatcgcga atacgctcag cctgaaccgc
    63001 cgtcgtaacc agtagaagaa ttaatgcaga gagaaattta atcaccacag cctcacttac
    63061 attggcgaca gattaaggaa gaaacgttgc aaccagccca tattttgcgc ttcgttaatg
    63121 tagccattgc ctacgtattc aatgcgcgca tccgccacct gagtagacgg tacggtattg
    63181 ctgccgctga tagtgcgtgg attaactaca ccagagaagc gaataaattc ggtaccctga
    63241 ttaatggcga tctgtttttc acccaccaca tgcaggttgc cgttgaccag tacctggtca
    63301 accgtcaccg tcaacgtgcc gctaaaggta ttgctggcat tggccccgcc ttttccgttg
    63361 aacgtgttac caccggaggc ttcgacatcg gcacgagcgt taccaaacag cccctgcaaa
    63421 tagcgcggca cagtatcaaa gccaaaatta gatttaccgt cacggctggc attcgcagag
    63481 gagcttttgc tggcgctgac gttctcctgc aacacgatgg tcagcgtatc gccaatattg
    63541 cgtggtcgac gatcttcaaa cagcggttga tagccatagt taatcggctg agcagactgg
    63601 aaaatagaac cgttggcgac gggcgtcgga ccgggaaccg gttgtgcact ggtcgccccc
    63661 tgtaccagcg gcgtggaggg tatccaggcg cagccggtta gtgaaagcac caacaagctg
    63721 gaaatggcat aagtatgcgc agcatttttt tgcatggcta tcatcttcaa aaatcagtaa
    63781 accggtgaat ctgccaccgg ttatgcctta gagttgcgtc agtttttgca gcatctgatc
    63841 ggtggtggat accgctttac tgttgatttc gtaagcgcgt tgcacctgaa tcatattgac
    63901 cagttcttcc gccacgttga cgttagacgt ttcaacatac ccttgataca gcagtcccgc
    63961 gccgttcagg cccggcgtgc tttcgttcgg tgcaccggag gattgcgttt cggtgtagag
    64021 gttttcgcca atactctcca gtccggtatc attcataaag gtggtgagat tgagctgccc
    64081 aacctgaacc ggagctgcct ggccttgttg ggttacgctg accacgccat cacgaccgat
    64141 ggtgatactt aacgcattcg ccggaatggt gatcgctggc tgcacctgaa aaccaccagc
    64201 cgtcaccagc tgcccgttct gatccacctg gaaagagccg tcacgggtat aggctgatga
    64261 gccatctggc aacatcacct ggaaaaagcc ctgcccttta atcgcgacat ctttgctgtt
    64321 attggtttgc gacaggttgc cctggctgtg taagcgttca gtggcgaccg ggcgtacccc
    64381 cgtaccgatt tgtaatccgg atggtaaggt ggtttgttcg gaagactgtg cccccggctg
    64441 gcgaatggtt tgataaagca gatcttcaaa caccgcgcgc tgacgcttaa aaccgttggt
    64501 actaacgttt gccaggttgt tggcaatgac gtccatattg gtttgctggg cgtcaaggcc
    64561 cgttttggcg atccataatg aactgatcat aaaatgtcct gtagtggatt agtgacaagc
    64621 agagcagaag cacgcgacgg tgcgaatttc ccctcaccct aacctctccc aaaatgggcg
    64681 agagaatagt ccgcgcgctt ttattgcaat gtcatcaatc gtttaattaa ctcattgaca
    64741 gcagttggtt ggcacggcct gcgttatcat cgacgctgct gatcaccttc atctgcattt
    64801 caaaacgccg cgcgctggca atcatgtcgc tcattgccgc aacggcattg acgttactgc
    64861 cttccagaac tcccgacatc acacgcaagg ttggatctgc ctgcagtacc ggcccacgcg
    64921 tggcctggct ttccgcgctt aaacgaaaaa tgccgtcgtc accgcgctgc acttcgctgc
    64981 ccgtggcttt caccagtttc agacgcccca ctggcgcaac cgtatttgcc ggatcgcccg
    65041 gattcagcgc cgagattgtt ccatcggcag caatagtgat ttccgcccct tccggcacag
    65101 caattggccc cgcctcgcct atcaccggat gcccctgaat tgtcagttgc ccggtgggat
    65161 caacctgaat gctgccatta cgcgtatacc cttcgctacc gtcatcggtc tgcacggcca
    65221 gccagccatc ctgctgcaac gcaacgtcca gcgggcgcga ggtgtaatcc atcttgccgg
    65281 gcgtcatgtc tgcacccggc gttgacgccg ttaccagcgt gcgcgtgggc agtgaaagcc
    65341 cttccaccgg cactgcgcgc aaggcgttta actgcgcgcg aaaaccgggc gtagaggcat
    65401 tggccagatt actggcggtt accgcctgtt gattcagcgt ctggctggct gctcccatcg
    65461 cggtataaat tgcgtgatcc attgagctat cccgtcagcg attagcgtaa gttaaccagc
    65521 gtgttgagga tctggtcctg ggttttgatg gtctgggcgt tagactgata gttacgctgg
    65581 gcaacgatca tattgaccag ttctttactg agatcgacgt tggacgcttc cagcgcaccg
    65641 ttggtcagcg taccaaagtt gcccgtcccg gcagtcccca acagcgccac gccagaagat
    65701 tgcgtcgcag accagacgtt gtcaccttca gatgccagac cttcgttgtt ggcaaagttc
    65761 gccagtacaa tctgccccag cagttgggtt tgttcgttgg aatagttgcc gacaaccgta
    65821 ccgtcatcat tgatttgata actcaccaga tcacccggtt tgtagccatt ctgggtggtt
    65881 gccacgatgt tgttagcgcc ggtattttgc tgcatagaat tgaggaagct caggctaaac
    65941 gtggcgggat ctgcgccgtt aattgcgccg gtggtaatat cctttgttgg acctgaggtc
    66001 agaacgccat tggcattaaa caccagcgtc gttgcagggt tagctgtgcc tgttggatca
    66061 ctgctatcca gggtgtaaac atcccagttg ttatccccgg tcttcacaaa ataaacgctc
    66121 atatcatgag cattaccctg actatcgaaa acagtcaccg aacctttttt gttatagcta
    66181 tccgcattgc tggcatcgaa tgctttaaca gagggaagcg gatcactgga attcaggttg
    66241 atctgcatcg acgccgtggt agtagttttc gctgccatca gggtattcgg aatcgaaata
    66301 ttggtcggat tcgccccttg ctgaatagtc ggcggcgtac cggttgccgg gtaacccgtc
    66361 agctgtaaac cttgcatatt caccaggtta cggttttcat ccagcttaaa ttgtccgtta
    66421 cggctgtaga acaccgaacc gttgctgtct accagacgga aaaaaccgtt ctggctgata
    66481 gcaacgtcca gacctcgccc ggtgttggtg gtcgtgccat cggtaaagtc ctgagtgata
    66541 ccggcaactt ttacccccag tcccactttc gaaccggcaa acatatcggc aaaagaggcc
    66601 gtgcctgatt taaagccgta ggtggcggag ttggcgatat tgttgccaat aacatcgagg
    66661 ttggtggcgg cagcgtttaa tccgctaacc gcttgagaaa aggccatgac tgactcctga
    66721 aatgtgaagg cttaaattat ctgccgtact tcgtcgaggg tggtggtgcc gtaagtgccg
    66781 agatccagcg tattaccgtt gttgccgcgg atcacaccct gcaccagagc aaactgcagc
    66841 ggctgggcaa ccagttgtgt accaccgcta ctggcgctaa tcgctacatt gtaagaaccg
    66901 ttcggcgcag tgctgccgtc agtcaacgta ccgtcccagg tgaaactgtg gactccggca
    66961 gtcagttcac cgatatcaat ggtacggaca actgcaccgt ttttatcggt gatggtggcc
    67021 gtcactttgt ctgccgcctg ttgcagctca acaccaaacg gcgtggtcgt ggtcacagcc
    67081 ccttcatcac tgccggttcc cgcaagaact gtggtaccgg ggatcatcac gccgtgaccg
    67141 atcaggttac tggcctgtaa cgactggctg ttatcaatct gtccggaaat agatccgagc
    67201 atggtattga gtttttcaat cccgcttacc gtgctgattt gagccaattg cgacgtcagc
    67261 tcgttgtttt ccattggatt ggtcgggtcc tggtttttca gctgcgccac caacaaagtc
    67321 agaaaactgc tttgtaaatc tgcggcgttg ctgcccgtga gcgaactact actggtggtg
    67381 cttacgccgg tatttgtcgg atcggtggtg gttaccgcaa tggacatagc tttctccttt
    67441 attgaccgag cgtaagggtt ttcagcatca tgcttttcac cgtgttgagc acttcaacat
    67501 tggcctgata gctgcgtgac gccgacatgg tgttaaccat ctctccgacg acatcaacgt
    67561 ttggcatttt cacgtagccc tttgcatccg ccagcggatt acccggttca taaaccagtt
    67621 tgtccggggc ctgactttct ataacatcgg ccacctttac gccgcctgtc gcagcacctg
    67681 gcgcagcgtt aacctgaaat accacctgtt ttgcccgata tggctgtcca tcgggaccgg
    67741 tcaagctatc agcattcgcc agattactgg ccgccacgtt caggcgctgg gactgggcag
    67801 ttaacgccga accggcgata tcaaaaatat tcagcagtgc catccgttaa tttccgctct
    67861 gtaaaacgtt catcatgcct ttgatttgcc cgctcaacgc gctaaggctc atctggtatt
    67921 gcaggctgtt atcggcaaac tgggtgcgtt cgcgatccat atcgacggta ttaccgtcaa
    67981 gcgaaggctg gtccggaata cggtattgca gttctgcggt aggaggcgtc agcgcctgcg
    68041 ccggaatgtg ttgcgttgag gtcatcgtca gagcaaccac actggttgca tcccgtccac
    68101 gttgcatgac ttttttaagt tcactggcaa aatcgatatc gcgagcctga taaccagggg
    68161 tatcggcatt ggcgatgttt gctgccagca cttcctgacg ctgggcgcgc agattgagcg
    68221 cctcttgttg aaaacgtaag gcggcgtcga gcttatcgag catatctcct ccgcaggtat
    68281 caaaattctg ccatcagctt aaatgccttt acgcgcgcgt tatcggcgga ataaacgcaa
    68341 aatgggtcgc tatttatgcc gttgatggtc attgcggaca ggtacaattc acgttgtaga
    68401 aatggctggg ggcgaaaatg ctgacaataa aacgtagcgt gacgatcatc gcgatactgt
    68461 tcagtccgtt aagtacggcg agcaatctca catcgcaatt gcacaccttt tttagcgccc
    68521 agctcgcggg ggtaagtgat gaggttcgtg tttctattcg tacagcgccc agtctactgc
    68581 cgccgtgcga gcagccattg ctttcgatga gcaataattc ccgcctgtgg ggcaatgtga
    68641 atgtgttggc acgctgcggt aacgacaaac gatatttaca ggttaatgtg caggccacag
    68701 gaaattatgt ggttgccgca atgcccattg tgcggggagg aaagctggaa gctggcaatg
    68761 tcaaactgaa acgcggacgg ctggacacct tgccaccgcg tacggtactg gatatcaatc
    68821 aacttgttga tgccgttagc ctgcgcgatc tatcacccga tcaacctatc cagttaaccc
    68881 agtttcgcca ggcatggcgg gtaaaagcgg gacaacgcgt caacgtgatc gccagcggtg
    68941 atgggtttag cgccaacgca gaaggtcagg cgctgaacaa tgctgccgtc gcacagaatg
    69001 cgcgggtgcg catggtatcg ggacaggtgg tcagcggcgt tgttgatgca gatgggaata
    69061 ttcttataaa cctgtaagct gttaaagatt acccatccct tgccgataaa taagcaacac
    69121 atgataaaag cgccctcaat gaggaataaa ccatgagtat tgatcgcact tcgcctctga
    69181 agcccgtaag caccgttcaa ccgcgcgaaa ccactgacgc gccggtaacg aacacccggg
    69241 cggcaaaaac aaccgcctcc accagcacta gtgtgacgtt aagcgacgcg caagcaaaac
    69301 tgatgcaacc cggcagcagt gatatcaatc ttgaacgtgt cgaagcgtta aaactggcga
    69361 ttcgtaacgg tgaactaaaa atggacaccg gcaaaattgc cgatgcgctg atcaacgaag
    69421 cgcagcaaga cttgcagagt aactgatcgt atgacgcgtc ttgcagagat cctcgaccag
    69481 atgtccgctg tgcttaacga tctcaaaacg gtaatggatc aagaacagca acatctctct
    69541 atggggcaga tcaacggcag ccagttgcaa tggattacag aacaaaaaag ctcactgctg
    69601 gcgacgctgg attacctcga acagttacgc aggaaagaac ccaattcagc aaatagcgtt
    69661 gatattagtc aacgctggca ggaaattact gtgaaaacgc agcaactacg ccaaatgaat
    69721 caacataacg gctggttact ggaaggacag attgagcgca atcaacaggc gctggaaatg
    69781 ttgaaaccgc atcaggaacc gacgctatat ggagcgaacg gtcagacctc aacaacccat
    69841 cgcggcagta aaaagatttc gatctgaaga ttatctccgg cctgcactgc aggccggaat
    69901 gcattgttac accgtccggc gggcaaactc tttaactttg aagcccagta ccgccagtgc
    69961 agcgaagtac gcggcaatcc ccgccagcac gaccgccatt aaacgcagta aacgccaggg
    70021 catggtaccc aatgaccact ccggcatgat atgtaacata cctaaaagca cgccagacat
    70081 caccagtacc gccaccacca gacgcaacag aaacgccatc cagccgggtt gcggggtaaa
    70141 gattttctgt ttacgcaact gccagtaaag cagcgaagca ttcagacacg ccgccagacc
    70201 aatagaaagt gacagcccgg catgtttcaa cggaccaata aacgccaggt tcatcaattg
    70261 cgttaaaatc agcgtaacga tggcaatttt cactggcgtt ttaatgtcct ggcgggaata
    70321 aaagccagga gccaacactt tcactacaat caggccaatc aaacccaccg agtaggcaat
    70381 taacgcccgc tgggtcatca gtgcatcaaa ggcggtaaat ttaccgtact ggaacagcga
    70441 aacggttaac ggaccggaaa gaatgcccaa cgcaaccgca ctcggcagcg ccaacaggaa
    70501 acaaagacgc agcccccagt ccatcaaacg gttgtattca tcatgattgc cactggcaaa
    70561 acttttcgac agcgacggca gcaaaatggt gccaagcgcc acgcccagta caccggacgg
    70621 aaactccatt aagcggtcgg cgtaatacat ccacgacacc gaaccggaag caagaaacga
    70681 ggcaaaaatg gtgttgatga ttaaggagat ctggctcaca gagacgccaa ggatcgccgg
    70741 tcccatctgt ttcaccacgc gcattgctcc ggcatcgtgg aagttaatgc gtggcaaaac
    70801 cagcatgccg atcttcttca gatgcggtag ctgatacacc agctgcagga tgccgccgac
    70861 cgtaacagcc caggccagcg ccagcaccgg tggattaaag tacggcgcgg caaacagcgc
    70921 aaagccaatc atgctgatat tgagcaatgt cggggcaaac gccggaattg agaagcggtt
    70981 ccaggtattc agaatcgctc ccaccagcga cgccagggag atcagcaaga tatagggaaa
    71041 ggttatcttt agtagctggc tggtcagggc aaatttgtcg gcagtgtcag cgaagccagg
    71101 cgcggtcacc atgatcaccc acggtgcagc gagcatgcca gcgaccgtca caaccgccag
    71161 cgcaagtgtc agcaggccag aaacataaga gacaaagacc cgcgtggcgt cttcaccctg
    71221 cttgctttta tattccgcca gaatcggtac aaatgcctgg gaaaatgccc cttcggcaaa
    71281 aatacggcgc aacaagttag gaagtttaaa agcgacgaaa aaggcgtcgg ttgccatccc
    71341 tgcgccaaag attctggcga caattgcgtc acgtgcgaag ccaagcacac gcgaaaacat
    71401 ggtcatcgag ctgacggcgg ccagcgattt taataaattc atcggtgttc taatccagac
    71461 ccacgggcaa aacgcctgca aggcaggcgc tgaaagaggc gaatagtcta cctggattat
    71521 ggtgaattgc taccgccaga tgttacaggg tttattcact catcgcatcg cgccagatct
    71581 tgtcaacgat acgttgcgcc agcactgcct gttcgccggc ggtttgcgga actgtctgat
    71641 tttgcacgca ttcaatgaag tgccgcgcac agccgacaaa tccacgttgc tcaagcgtac
    71701 tctgccaacc aggaatcggt ttatgcacta cgccctgccc gcgctcctca cgccattcgc
    71761 gcatatccgt aatgtcgatg agcgcaccgt cagtcacggc ctgcacggtt tcacgctgac
    71821 ttccggcacg gcgatgcata caggtggtga tctgcaaagg accggccgaa aaatggtgct
    71881 cggcaaacag catttcgcca gcgtcattag tcagtagcgt accgccatcc agagaggctt
    71941 taccgcccga caaccacagc gcggtatcca ccacatgcag ataatcatcc agcaacgtga
    72001 aataaagatc gtgtggcccg acgctattgc tacgatgttt atccattctt agcgaggctg
    72061 cggtggcgag ttgcgttttt aactcaccgt agagtggtgc gaaacgacgg ttaaaaccga
    72121 ccatcaacgt caattttttc cgcgccgcca gttccaccag ccgttcagca tcgcgcagat
    72181 tttctgccag cggtttatcg acacagacat gtacccccgc attgagtaac gtactgacca
    72241 cgtcaaagtg gctggcggtg ctggaatgca caaaaaccgc atcgcaactg gcggcaaggc
    72301 tggataacga atcagcataa ggaatgcgcc agctgtcaca aattggcagg gctttggcgc
    72361 gcgtaggcga ccacgcacct tgtaacgtcc agtcagacgc tgccgccagc accggtaacc
    72421 acgctttttg cgcgatgccg cctaacccca ctacgccgat acgtaatttt ttcactttaa
    72481 tctcccagat gggccagcaa cgaatcaaga cgctgtttca gttctgccac ttcgatttcc
    72541 agggcttcga cgcgtgcctg taaatcaccg tcaaccgcgt tcgacatatc catcaccgcc
    72601 ggctgatctt caacctcacc actgaaaaga tgcatgtagc ggctttcacg tttacccggt
    72661 tcgcgggcca gacgcaccac aaaaggacca tcttcgcgat ttgccagttg ttccagcgtc
    72721 gacttcactt ccgccatatc gctgaattca tacattcgcg cggcgcggct gcgcagttca
    72781 cccggcgtct gggcaccacg caataacaac gtggtgatta acgccacttc tgcggcgctc
    72841 agtttcagat cgccaaattc tgaattacaa aaacgttgct catatttggt gacccgatta
    72901 ccaaaaccgc tcaccgtgcg tagataatga cgtttgacca gattatccag ctgttcctgc
    72961 acttcagatt cactcagatt cataaccggt tcacggttcg ttttctgatt acaggccgtg
    73021 actacaccat tgactgagag cgggtattgc tccggcgtgg tcacctgctt ttccagcaag
    73081 cagccaatca cgcgagcttc cagggcagta agttgatatt tcatgagatt ctccttagcg
    73141 gccgggcgtc cagtctgggg tagttaatgc cgtcagtacg tgatcgcgcc attgtccatc
    73201 aatcaacaga tagtctttcg catagccttc tttttcaaaa cccagtcgcg ccagtaaatc
    73261 accgctgcgt ttattgtgcg gcatataatt agccataatg cgatgaatat gttgggtgcg
    73321 ctgcatataa cgaatggctg cggtcagggc ttcaaacatg agtcctttgc cctgccattt
    73381 ttgcccaatc gaataaccga gatagcaggc atgaaaagag ccacgaacaa cattggaaaa
    73441 attggcaacg ccaataatct ctttttcgtc cgggtcgaat aagccaaagt agaaagctga
    73501 accttgttta tgaaattcgt taatcatccc tagcctggcc tgccagcctg atggataaca
    73561 gtggctttcg tcgcgcactg gctcccaggg cttgaggaaa tggcgattct ctgcgtaata
    73621 atccgcaaga cgccaggcat cacgatcatg caccagacgc acgaccagtc ggtctgtggt
    73681 taagcgcact tttggcacgt tactgcgata gccaaacatt ctatacctac tccttcccgt
    73741 aacgtcttta atacgctgta agtattacta tacctgcgca accagaccct gtgaaaagtc
    73801 cagaatgcca ttttctgcat tattcacata tttgataaaa actctctatc aaagcgacgt
    73861 tttgataaaa aaatattgtc cccgaagtga tgggaaaagt cttagcggca atgcagaata
    73921 gaaagtgctc atcttttatt tcccgggagg ggaaatgtcc cgcgtgtcgc aggcgaggaa
    73981 cctgggtaaa tatttcctgc tcatcgataa tatgctggtc gtgctggggt tctttgttgt
    74041 cttcccgctg atctctatcc gcttcgttga tcaaatgggc tgggccgccg tcatggtcgg
    74101 tattgccctc ggcctacgcc agtttattca gcaaggtctg ggtattttcg gcggcgcaat
    74161 tgctgaccgc tttggcgcca aaccgatgat tgtcaccggt atgctgatgc gtgccgccgg
    74221 attcgccaca atgggtatcg cccacgaacc gtggctactg tggttttcat gcctgctttc
    74281 gggactcggc ggcacgttgt ttgatcctcc gcgttcggcg ctggtggtga aattaatccg
    74341 tccacagcag cgtggtcgtt ttttctcgct gttgatgatg caggacagtg ccggtgcggt
    74401 cattggcgca ttgttgggga gctggctgtt gcaatacgac tttcgcctgg tctgcgccac
    74461 aggggcagtt ttgtttgtgc tgtgtgcagc gttcaatgcg tggttgttac cggcatggaa
    74521 actctccacc gtacgcacgc ccgttcgcga aggcatgacc cgcgtgatgc gcgacaagcg
    74581 ttttgtcacc tatgtcctga cgctggcggg ttactacatg ctggctgtac aagtgatgct
    74641 gatgctgcca attatggtca acgacgtggc gggcgcgccc tctgccgtta aatggatgta
    74701 tgccattgaa gcgtgtctgt cgttaacgtt gctctaccct atcgcccgct ggagtgaaaa
    74761 gcattttcgt ctggaacacc ggttgatggc tgggctgttg ataatgtcat taagcatgat
    74821 gccggtgggc atggtcagtg gcctgcaaca acttttcacc ctgatttgtc tgttttatat
    74881 cgggtcgatc attgccgagc ctgcgcgtga aaccttaagt gcttcgctgg cagacgcaag
    74941 agctcgcggc agctatatgg ggtttagccg tctgggtctg gcgattggcg gcgctattgg
    75001 ttatatcggt ggcggctggc tgtttgacct gggcaaatcg gcgcaccagc cagagcttcc
    75061 gtggatgatg ctgggcatta ttggcatctt cactttcctt gcggtgggtt ggcagtttag
    75121 ccagaaacgc accgcgcgtc gtttgcttga acgcgacgcc tgatttgata ctcccccctg
    75181 actcctccat actgaaagtg aactgacagc caaatggagg agtcacgtga agctattcat
    75241 ttacgatcac tgcccttact gcctcaaagc ccgcatgatt ttcggcctga aaaatatccc
    75301 cgtcgaatta catgttctac tcaacgacga cgcagaaaca cccacccgga tggtcggtca
    75361 aaaacaggtt cccattctgc aaaaagatga cagccgctat atgccagaaa gcatggacat
    75421 cgttcactat gtcgataaac tcgacggcaa accgttactg accggcaaac gttcccctgc
    75481 cattgaagaa tggctgcgca aggtcaatgg ctacgccaac aaactgctgt tgccgcgttt
    75541 tgccaaatcg gcatttgatg agttttctac tcctgccgcg cgcaaatatt tcgtcgacaa
    75601 gaaagaggcc agcgcgggta attttgccga cctgctggcc cactctgacg gtctgattaa
    75661 gaatatcagc gatgatttac gtgcgctgga caaactgatc gtcaaaccga acgccgtgaa
    75721 tggcgaactt tcggaagatg atattcagct atttccgctc ctgcgtaatc tgacgctggt
    75781 agccggaatt aactggccaa gccgcgttgc tgattaccgc gataatatgg cgaaacagac
    75841 acaaatcaat ttgttatcat caatggcgat ttaatcctga cccgccgcgg cagcctgtat
    75901 tcgcgggttg ccgccgtttt cagttttttc tgctggcgcg tttatcgctg gtgacacatg
    75961 ctgcgttgtg tcaggatatt gacgcagatt tcatgtcgag gactaccatg aacaagtttt
    76021 tatttgccgc tgcattgatc gtcagtggcc tgctcgttgg ctgtaatcaa ctcacccaat
    76081 acaccatcac cgaacaagaa attaaccagt cgcttgcgaa acataataat ttctcaaaag
    76141 atatcggttt acccggcgtg gctgacgccc atattgttct gacaaacctg accagccaaa
    76201 ttggtcgcga agagccgaat aaggttaccc taaccggaga cgccaatctg gacatgaact
    76261 ccctgttcgg tagccagaaa gcgaccatga aactgaagct gaaagcgctg cccgtgtttg
    76321 ataaagaaaa aggtgcgatc ttcctgaaag agatggaagt ggtcgatgcg acggtacaac
    76381 cggaaaaaat gcaaacggtg atgcaaacgt tgctccccta tttgaaccag gcattacgca
    76441 attactttaa ccagcaacct gcttacgtcc tgcgcgaaga tggcagccag ggcgaagcaa
    76501 tggcgaagaa actggcgaaa ggcattgaag tgaagccagg cgaaattgtc attccgttta
    76561 cggattaatc acgagggcgc attcgcgccc tttatttttc gtgcaaagga aaacgtttcc
    76621 gcttatcctt tgtgtccggc aaaaacatcc cttcagccgg agcatagaga ttaatgactg
    76681 caccatccca ggtattaaag atccgccgcc cagacgactg gcaccttcac ctccgcgatg
    76741 gcgacatgtt aaaaactgtc gtgccgtata ccagcgaaat ttatggacgg gctatcgtaa
    76801 tgcccaatct ggctccgccc gtgaccaccg ttgaggctgc cgtggcgtat cgccagcgta
    76861 ttcttgacgc cgtacctgcc gggcacgatt tcaccccatt gatgacctgt tatttaacag
    76921 attcgctgga tccgaatgag ctggagcgcg gatttaacga aggcgtgttc accgctgcaa
    76981 aactttaccc ggcaaacgca accactaact ccagtcacgg cgtgacgtca gttgacgcaa
    77041 tcatgccggt attagagcgc atggaaaaaa tcggtatgcc gctactggtg catggtgaag
    77101 tgacacatgc agatatcgac atttttgatc gtgaagcgcg ctttatagaa agcgtgatgg
    77161 aaccgctacg ccagcgtctg actgcgctga aagtcgtttt tgagcacatc accaccaaag
    77221 atgctgccga ctatgtccgt gacggaaatg aacggctggc tgccaccatc actccgcagc
    77281 atctgatgtt taaccgcaac catatgctgg ttggtggcgt gcgtccgcac ctgtattgtc
    77341 tacccatcct caaacgcaat atccaccaac aggcattgcg tgaactggtc gccagcggtt
    77401 ttaatcgtgt attcctcgga acggattctg cgccacatgc acgtcatcgc aaagagagca
    77461 gctgcggctg cgcgggctgc ttcaacgccc caaccgcgct gggcagttac gctaccgtct
    77521 ttgaagagat gaatgctttg cagcactttg aagcattctg ttctgtaaac ggcccgcagt
    77581 tctatggctt gccggtcaac gacacattca tcgaactggt acgtgaagag caacaggttg
    77641 ctgaaagcat cgcactgact gatgacaccc tggtgccatt cctcgctggg gaaacggtac
    77701 gctggtccgt taaacaataa aaatcgtagc ttcctgttgt cattaggtta ttttacctgt
    77761 ataaataacc agtatattca acagggggct attatgcgaa ttgaagtcac catagcgaaa
    77821 acttctccat tgccagctgg ggctattgac gccctggctg gcgaactttc ccgccgtatt
    77881 cagtatgcgt ttcctgataa tgaaggccac gtatcggtac gttatgccgc agcaaataat
    77941 ttatcggtta ttggcgcgac aaaagaagat aaacagcgca ttagcgaaat tctccaggaa
    78001 acgtgggaaa gcgccgatga ctggtttgtc agcgaataat atgcagtgat ttttgttttt
    78061 gccgggtcgc cccggctttt ttattttact tgcgaattgt gagtacaaaa tttctacact
    78121 tcctcaaaat aattgcacaa tatgctaaaa aaatatgaat gacatgctgt tttattgttc
    78181 atataaatct taaaagcaga aatttatctg ttcccccctt taaaaattcg gtgaataccc
    78241 ttacttattg gtatactgaa gttgcttcag ataaaaacgc attgaacctc gaataacgtt
    78301 gtctagtaac acgaattagg gggccatgat ggaaaaaaat aatgaagtca ttcagactca
    78361 tccgctcgta gggtgggaca tcagcaccgt tgatagctat gatgcgctga tgttgcgttt
    78421 gcactaccag accccaaata agtccgagca ggaagggact gaagttggtc agacgctctg
    78481 gttaaccact gatgttgcca gacaatttat ttcgatatta gaagcaggaa tcgccaaaat
    78541 tgaatccggt gatttccagg taaacgagta tcggcgtcat taacatgaca tgaccatcca
    78601 cccaaaaggc acctcaccgg tgcctttacc atttctgggt tgtatatctg cattcagtta
    78661 attactctgc ttaaaccatg agagcagaga gaaaaaaatg aaatacgatc tcatcattat
    78721 tggcagcggt tccataggcg ctgccgccgg gtattatgca acccgcgccg gtttaaacgt
    78781 gcttatgacc gacgcccata tgccaccaca tcaacacggc agccaccacg gcgatacgcg
    78841 attaattcgc catgcttatg gtgaaggtga aaagtatgtc ccgctggtcc tccgcgcgca
    78901 aatgctgtgg gatgaacttt cccgccacaa cgaagatgat cccatttttg tacgctctgg
    78961 tgtcattaac ctcggtccgg ctgactccgc atttctcgcc aacgtcgccc acagcgccga
    79021 acagtggcaa ctcaacgttg aaaagctcga cgcgcaaggg attatggccc gctggccaga
    79081 aatacgcgtc ccggacaact acatcggttt atttgaaact gattctggtt ttttgcgcag
    79141 cgaactggcg attaaaacct ggatccaact ggcgaaggaa gcgggctgtg cgcagctgtt
    79201 caactgcccg gtcaccgcaa ttcgtcatga cgatgatggc gtaactattg aaacggctga
    79261 cggtgagtat cgggcgaaaa aagcgattgt ctgcgcggga acatgggtaa aagacctact
    79321 cccggagctg cctgtccagc ccgtacgcaa agtatttgcc tggtatcagg ccgatggtcg
    79381 ctatagcgtg aagaataaat tcccggcgtt taccggtgaa ctgcccaatg gcgatcaata
    79441 ttatggtttt ccggcagaaa acgacgcgtt gaagattggc aaacataacg gaggccaggt
    79501 tatccattca gcggatgaac gtgttccgtt tgcggaagtg gtcagcgatg gttcggaagc
    79561 cttcccgttc ttgcgcaatg tattgccggg tatcggttgc tgcctgtacg gcgctgcctg
    79621 cacctatgat aattcgcctg acgaagattt tattatcgat accctacccg gccacgataa
    79681 tacactgctc attaccggcc tgagtgggca cggttttaaa tttgcgtcag ttttagggga
    79741 aatagctgcc gattttgcgc aagacaaaaa aagcgatttt gatttgacgc cattcaggct
    79801 ttcccgcttc caataatcat cattacggcc tccagaatga ggccgttttt acaggagtat
    79861 ttaatgcgtc ggctgttgca ctatctcatc aataatattc gcaagcatct gatgctttat
    79921 ctttttctct ggggattgtt ggcaattatg gatctgatct atgtgtttta tttttagttt
    79981 tccgcactga cataaactga caaatattta atctcccttt catttagcgt gaaaaattga
    80041 atgagattat tcctgcttca acagcactca ccagacatct ctgaagctga acccactaaa
    80101 cttatgaaga ttctttcatt attaattcaa aattattgaa ataaaaataa atatcattca
    80161 atttgttatt tttgtgttgc aattcattct ccgacacgcc attttctttc tctcgcaaag
    80221 tcgttttgga tgcacttatg tcattcacaa atacccctga acgctatggt gttatatctg
    80281 cggccttcca ttggctaagc gcaattattg tctacggcat gtttgcttta ggtctgtgga
    80341 tggtcacgct cagttattac gatggctggt atcacaaagc acccgaactg cataaaagca
    80401 tcggtatttt gttaatgatg ggactggtta ttcgcgttct gtggcgtgtc atatctccac
    80461 cgccgggtcc gctgccgagt tattcgccca taactcgtct tgcagcaaaa gctggacatc
    80521 tcgcattgta cctattgctg ttcgccatcg gcatcagcgg ctatctgatc tcaactgccg
    80581 atggtaaacc gatcagcgtt tttggctggt ttgacgtccc cgcgaccctc gccgacgctg
    80641 gcgcacaggc tgactttgcc ggtgccctgc atttttggct cgcgtggagc gtcgtagtac
    80701 tgtccgttat gcacggattt atggccctga agcatcattt catcgataaa gacgacactc
    80761 tgaagcgcat gctgggaaag tcgtcatctg actatggagt ataaaaaatg aaaaaaagcc
    80821 tgcttggttt aaccttcgct tccttgatgt tctctgccgg ttcagcggtt gccgccgatt
    80881 acaaaattga caaagaaggt cagcacgcct ttgttaactt ccgcatccag catcttggct
    80941 atagctggtt atatggcacc tttaaagatt tcgacggtac ttttaccttt gatgaaaaaa
    81001 atccagctgc cgataaagtg aatgtgacaa ttaacaccac cagcgtcgat actaatcacg
    81061 ccgaacgcga taaacatctt cgcagtgcag atttcctcaa tactgcaaaa tatccacagg
    81121 caacattcac ctccaccagc gtgaagaaag acggtgacga attggatatt accggcgatc
    81181 tgacgctgaa tggcgtaacc aaacccgtca cgctggaagc gaaattaatt ggtcaaggcg
    81241 acgacccgtg gggtggtaaa cgtgcaggct tcgaggccga aggcaaaatt aagctcaagg
    81301 acttcaatat caaaacagat ttaggtccag cttctcagga agtggatctg attatttcag
    81361 tggaaggcgt acagcagaag taagagtgaa atgttgccgg atggcacgca tccggcaatg
    81421 atatttattc tgttggatca ggaatgccca gtgttgtatt cagacgtcca cgagacttat
    81481 taaagatctt attgccattt tcacgtcctg cccgacggcg tcgctgttct tcaggcggta
    81541 acgcgctttc ttcgcagcaa atctcactac aacaaccttt gtatttttcc gcacatactg
    81601 gacactgaat aaaaagcagg tggcagccat catttttaca gttggtatgg ctgtcgcacg
    81661 gcgcaccgca ctggtggcaa tgcgcgataa tctcatcaga tatacgttcg cccatccgct
    81721 cgtcaaaaac aaaatttttg ccaataaaac gtaccggtaa accctgctcg cgcgccttgc
    81781 gggcgtattc aataattccg ccctcgatat gccagacttt attgaatccg ttatgtttca
    81841 tccaggcact ggccttttca caacgaatgc cgccggtgca gtacataacg atttttttat
    81901 ctttatgtgc ctgcatcatc tcgactgctt ttggcagctg ctcacggaag gtatctgccg
    81961 gaatttccag cgcgttttca aagtgcccca cttcatactc atagtggtta cgcatgtcga
    82021 taaacaatgc atcgggatcg tcaagcatgg cgttcacttc cgccgcttgc agatactcac
    82081 ccacattgct ggcatcaaag tgaggatcgt caataccgtc ggcaacgata cgatcgcgga
    82141 ccttcatgcg cagtacccag aaggatttcc cgtcatcatc caacgcgata ttcaggcgta
    82201 agccctctaa agccgggtcg aaggcataaa gctgcgcgcg aaatgtttca acattgctct
    82261 caggtacgct gatttgcgcg ttaatgccct catgcgccag atacactcgc ccaaaaacat
    82321 tcagcgcggt aaacagctga tataaagcgt cacgggtcgc cttaggatcg gcgatgtgga
    82381 aatacttata aaacgaaatg gtggttcgcg gttcgctctc agccaacatt ttggctttta
    82441 acgcgtcgtt ggaaatgcgg ttgtgtaaca ctggcatggt gtacggttcc tgcgagatgg
    82501 gaaagtaaaa atccgcggca tgatatagca attatcgata attaacatcc acacatttta
    82561 cgctacattt tagcattaaa aattatttgt tatttacaag cgcggcaatt tcgcccagtc
    82621 ttcagtcaca aattttggtt gcggacgaaa aaatgcgaca atacatacaa ttgcccgtat
    82681 aggttgaaaa acaggattga tatgacgaat ctacccaagt tctccaccgc actgcttcat
    82741 ccgcgttatt ggttaacctg gttgggtatt ggcgtacttt ggttggtcgt gcaattgccc
    82801 tacccggtta tctaccgcct cggttgtgga ttaggaaaac tggcgttacg ttttatgaaa
    82861 cgacgcgcaa aaattgtgca tcgcaacctg gaactgtgct tcccggaaat gagcgaacaa
    82921 gaacgccgta aaatggtggt gaagaatttc gaatccgttg gcatgggcct gatggaaacc
    82981 ggcatggcgt ggttctggcc ggaccgccga atcgcccgct ggacggaagt gatcggcatg
    83041 gaacacattc gtgacgtgca ggcgcaaaaa cgcggcatcc tgttagttgg catccatttt
    83101 ctgacactgg agctgggtgc gcggcagttt ggtatgcagg aaccggggat tggcgtttac
    83161 cgcccgaacg ataatccact gattgactgg ctacaaacct ggggccgttt gcgctcaaat
    83221 aaatcgatgc tcgaccgcaa agatttaaaa ggcatgatta aagccctgaa aaaaggcgaa
    83281 gtggtctggt acgcaccgga tcatgattac ggcccgcgct caagcgtttt cgtcccgttg
    83341 tttgccgttg agcaggctgc gaccacgacc ggaacctgga tgctgtcacg gatgtccggc
    83401 gcatgtctgg tgcccttcgt tccacgccgt aagccagatg gcaaagggta tcagttgatt
    83461 atactgccgc cagagtgttc tccgccgctg gatgatgccg aaactaccgc cgcgtggatg
    83521 aacaaagtgg tcgaaaaatg catcatgatg gcaccagagc agtatatgtg gttacaccgt
    83581 cgctttaaaa cacgcccgga aggcgttcct tcacgctatt aaatcttcca tgctggatgc
    83641 ttcagaatgg catccggcat taccacagaa aatccccctg atttagcgat aaaagctctc
    83701 tggattgcgc cccctggaag tcgggcgcat aattagtgtg cttatctttt cttcttatgt
    83761 tcaccgcgcc tggcgcacca acagcggatt gctatgtcac cctgtgaaaa tgacacccct
    83821 ataaactgga aacgaaacct gatcgtcgcc tggctaggct gttttcttac cggtgccgcc
    83881 ttcagcctgg taatgccctt cttacccctc tacgttgagc agcttggcgt taccggccac
    83941 tccgccctga atatgtggtc cggtattgtc ttcagcatta catttttatt ttcggccatc
    84001 gcctcaccgt tttggggtgg actcgccgac cgtaaaggcc gaaaactcat gctattacgc
    84061 tctgccctcg gcatgggcat cgtgatggtg ttgatggggc tggcacaaaa tatctggcag
    84121 tttttgatcc tgcgggcgct tcttgggtta cttggcggat ttgttcccaa cgctaatgct
    84181 cttatcgcca cacaagtacc gcgtaataaa agcggctggg cgctgggtac gctctccaca
    84241 ggcggcgtta gcggcgcgtt gctcggccca atggctggcg gtttgctcgc cgatagctac
    84301 ggcttacgtc cggtattctt tattaccgcc agtgtgctca tactctgctt tttcgtcacc
    84361 ctgttttgca tcagagaaaa attccagccg gtcagcaaaa aagagatgct gcacatgcgg
    84421 gaagtggtga catcacttaa aaacccgaaa ctggtactca gcctgtttgt cactacgtta
    84481 atcatccagg tggcgacggg ctcaattgcc cccattctga cgctgtatgt ccgcgaactg
    84541 gcgggtaacg tcagtaacgt tgcctttatc agtggcatga tcgcctcggt gccaggcgtg
    84601 gcggctctgc tgagtgcacc acgactcggc aaacttggcg atcgaatcgg acccgaaaag
    84661 atcctgatta cggcgctgat cttttctgta ctgctattga tcccaatgtc ttacgttcag
    84721 acgccattac aacttgggat tttacgtttt ttgctcggtg ccgccgatgg tgcactactc
    84781 cccgccgtac agacactgtt agtttataac tcgagcaacc agatcgccgg gcgtatcttc
    84841 agctataacc aatcgttccg tgatattggc aacgttaccg gaccattgat gggagcagcg
    84901 atttcagcga actacggttt cagagcggta tttctcgtca ccgctggcgt cgtgttattc
    84961 aacgcagtct attcatggaa cagtctacgt cgtcgtcgaa taccccaggt atcgaactga
    85021 tttttcgcct ttcatacttg caaaagcgga gaatcagcta tccttttccc tgaaacctca
    85081 tcaactcaaa gggagaatcg tgatgaccat gtacgcaacg cttgaagaag ccattgacgc
    85141 tgcacgcgaa gaatttcttg cagacaaccc cggcatcgac gccgaagatg cgaatgtgca
    85201 acagttcaat gcccaaaaat acgttttgca ggacggcgac atcatgtggc aagttgagtt
    85261 ttttgccgac gaaggggaag aaggtgaatg tttacctatg cttagcggtg aagccgcgca
    85321 aagtgtcttt gatggcgact atgatgagat agagatccgc caggagtggc aggaagagaa
    85381 tacattacat gaatgggatg agggggaatt tcagcttgag ccaccgctgg atactgagga
    85441 aggacgcgca gcagctgatg agtgggatga acgttaatta ctcatacggg ccatgatgaa
    85501 tgtcgatcgg cagcagtaaa gtatcaaaaa ccagggagaa tggcagatca aggatcgtga
    85561 cataacgcca ggcggagtca cgcacatccc attgcacacc gggataatat tggttgccat
    85621 gcccctgccc cggtatagtg cgactaataa tgctgccaca gccactcagc aaggtcacca
    85681 tgatgctcac cacaattaaa cgcatttgat acctcttccg taaaaaaata ccggcataac
    85741 gccggtattt ttattggctc gttgtttttg ccagatgtgg cgtgaacgcc ttatccgacc
    85801 cacaaaatct tgcaaaatca atacattgca ggagcgatgt aggcctgata agcgtagcgc
    85861 atcaggcaac tacgttttta ttgcgaagcc gcatccggtt tacgcaatgc cagtggattg
    85921 agctttatcc cttcgtaata actcacccat gaagaatatc tctcagggga attccagacg
    85981 cggaaatgca gacgggccat cgtcaccgga tcgcttagca gcaccaggcg acgatcgcga
    86041 ttcagcttct ctggcgtctc gttcagcgcc tgttcaacgt ggcggtcacg ggcgatttcc
    86101 agcaccttac tggcgcggtg acgcgcggtc gccattgcgg ttgccagagc gttgaatgac
    86161 gggttaaaca ctgcgtgcat aaaaccatca tcaagggagc gttgacggtt catctcaagg
    86221 aaccgatcgg tatcaaccag cacctgcggc ggtgaatact cttccgggat caggaacagt
    86281 ttccagcgtt tggtgcgcag accaacggtg gcacggctgg aaatcaccga aacaaacggt
    86341 gacaggatca acgagaagac aatcggagcc agccagaaca ggaaacgcag atccagccac
    86401 gccatcccaa cagcccacac taaccctaac agcagctgtg agccgtggcg tttgaacgct
    86461 tcaccccagg aagtggagtc atcatcacgc tgcggtgaat tccacaccac ttcccagcca
    86521 aggaacgcgc tgacgacgaa aaccgtatgg aacagcatgc gtaccggagc cagcagcacg
    86581 gaaaacagca cttccagcag caacgataat gtaacgcgcc agaagccgcc atattctttc
    86641 gttcctttgc accaaataag caaaatgctc aatagctttg gcaggaacaa cagcaccatg
    86701 gtcgaagcaa aaagtgcaat cgccagctca ggacgccact gcggccacac cgggaacaac
    86761 tgccgtggtt gcaggaagta ttgcggttcg gtcaacgcat gcactacctg caatgcagta
    86821 gagagcgcga ggaacataaa ccacaacgga gcggagagat aagacatcac gcccgtcagg
    86881 aacaccgcac ggtgaaccgg gtgcataccc ttgaccagga acagacggaa gttcatcagg
    86941 ttaccgtggc accagcggcg gtcacgtttt agctcatcaa gcaagttagg cggtaattct
    87001 tcataagaac ccgggagatc gtaagcaatc cagactcccc aacctgcacg gcgcatcaac
    87061 gccgcttcca cgaagtcatg tgacaggatt gaaccggcaa aggaaccttc gcccggcagc
    87121 ggagccagtg cgcagtgctc gataaacggt ttcacgcgga taatcgcgtt atgtccccag
    87181 tagtgcgact cgccaagttg ccagaagtgc aaaccggctg taaacagtgg cccatacacg
    87241 cgggtcgcga actgctgaca gcgcgcatac agcgtatcca taccggacgc tttcggcgac
    87301 gactgaatga tcccggcgtt cgggttggct tccatcaggc gcaccaggcc gcacaaacaa
    87361 tcaccggtca ttaccgagtc agcatccagc accaccatgt agctgtactg gctgccccag
    87421 cgacggcaga agtcatcgat attaccgctt ttacgcttca cgcgacggcg gcggcggcga
    87481 tagaaaatct gaccttcgcc accgacttca gcgataagct ccatccaggc tttttgctct
    87541 gcgacgcaga tatccgggtt ataactgtca ctcagaatgt agacatcaaa gtgtttggca
    87601 ttcccggtgg cttttactga ttcccacgtt gcacgcaggc cagcaaaaac acggttcacg
    87661 tcttcgttac agataggcat gatcaacgcc gtgcgatgct ccgggtttaa tggttcatcg
    87721 ccaactgttg acgcagatat actgtattta tcgcgaccaa taagcagttg caggaagccc
    87781 atcaacgccg tccagaatcc ggcggacacc caacagaaca gcaccgcaaa gaggatcagg
    87841 ataccggttt gcagcatata aggcagaagc tgcataaagg aaacccacac atcctgacca
    87901 accatatcca taggattaat cagcgcccaa ccctgataag gaagaatggt cttcatatac
    87961 caggtcgcga caacagtttg cgcgagcgtc aggatcaaca gaatgtaacg gcggatggta
    88021 ccgacggtac gccacttttg ctcgctctcc tgctcttctt tggtcaaacg agccagatag
    88081 cgcggcgtta catcgcgtcc acgcaggcga tcccagaaac ggcctaccgg gttggtacgc
    88141 cacgggtcgg gaaacatcga ggagcgtttt gcttctggca tcgccttaag ctgatcgcgc
    88201 ccttcgtcgt ctttaattaa ctgtccatca gcaagtgaat ctggccaggc ttgttccaga
    88261 cgcgccttta ccgagccttg cggggagtca tcctcccgcg cccaggtgcg gtgttcggca
    88321 tccagcgcct gatgaacggc gcggatatca gtcttcggca atgccgcttt ctcgcttgcg
    88381 gcgatgggca ttgcgtcaat gtactcagtt gtcttattca ttggcaggta actggtagct
    88441 ccaggtttca ctcaacgtct gatcggcatt caccagcgca gcacgcattt cagtggtttt
    88501 cttggcatct ttcactttca cacgcatcac cagacgccag cctttggtga ccgggttata
    88561 gcgcaccgtg ctttccacta tctcaccatt atcaccaatg ctggtttgcg ctgtgaccgg
    88621 ggtatcctct ggcagttttt tcatctctgc gccggtaaaa tcgaccacaa aggcgatagt
    88681 accgtcaggc tggcgaatca ggttcgactg cttcacatcc cccgttgaac gacgcgtttg
    88741 ttgcacccat gcgttatctg gcgcatgcag tttgtcttca tcacggctga aggtgatggt
    88801 gtatttaaag ttcatctctt tacccggctc cggcagctga tccggcgtcc agtaagcgac
    88861 gatgttatcg ttggtttcat cgttggttgg aatttccacc agctcaatgc tgcctttgcc
    88921 ccactcccct ttcggagtca cccatgcgct tggacggaga tcgtaacgat catcgagatc
    88981 ttcaaagcgg gagaaatcac gaccgcgctg caacagaccg aagccttgcg ggttttccat
    89041 cgagaagctg ctgaccgcta aatgtttcgg gttattcaac ggacgccaga tccattcgcc
    89101 attaccagca tggatagaca gaccgttaga gtcgtgcaac tccggacgat agttatttgc
    89161 aggcgacggt tggttcggcc caaacaggaa catactggtt aacggtgcaa cccccagttt
    89221 gccgacttta tcgcgcagat agattttcga ctgcacatcc acaaccgtgt cacgccctgg
    89281 cataactacg aatttgtaag cacctgtcgc gcgcggcgag tcaagcaatg cataaatggt
    89341 taaacgttta tcagtcggtt ttggacgctc gatccagaac tctttgaagc gtggaaattc
    89401 ttcacccgat ggcaaggcgg tatcaattgc caggccgcgg gcagaaaggc cataaacctg
    89461 acctgcacca atcacgcgga aatagctggc cccgagcatg ctgacgattt catcgttttt
    89521 atctttgctg ttgatcgggt aaagcacttt aaaaccggcg aaaccaaggt cttttaccgt
    89581 gtctttgtca tgctgaacat cgccgaaagt gaaataatcc gggctgtatt tgattcgttt
    89641 gactgcggtg gcagtcactt catttatttt gaccggggta tcgaagtaca taccctgatg
    89701 gtagaactcg agtttgaatg gggtcttcag attgttccag tacgctttgt catgattaaa
    89761 ctggatctgc tgatagtccg cgtatttcat gtcgcggaaa acggagggca agttgctttt
    89821 aggcgcctca tagcctttcc cggctaagga ttgagcttgc tttgcgacat catcaatact
    89881 gaaagcccag cttgaagagg tatacagggt taacattact gcagcactca accaacgcat
    89941 tttcatcatt tgtagtttat gtttcataat tagtaagcac ttcccccttt gtgtgcttat
    90001 atcgatccga tctattttaa tggataacca gccattccga caacagaatc ccggtatcgt
    90061 tcagcacgct ggctcatgga ttaagcacct gattgcaacc gttttcactt tccgtgcttc
    90121 tcctaaagac agaagcatcg acttcgtgta gggtttgcca gcaaatttat ttatcaaccg
    90181 tcttacagac gcttccattc tggttagtgg tagcgatgat gctatgcata aaaaccttga
    90241 agcctgcgtc tggcgcggtc aggtcggtgt cgctatggca acaagcctaa aggcataacc
    90301 cgacagggat aagacgaaaa atccgagatt agttaaccat atatgaatcc agtacccgcg
    90361 caacgtgaat atttcctcga ctccatccgc gcctggctga tgttgttagg gatccctttt
    90421 catatttctt taatctattc gagccataca tggcatgtga atagcgccga accgtcattg
    90481 tggctgaccc tttttaatga cttcatccac tcgttccgca tgcaggtatt tttcgttata
    90541 tccggctact tttcctacat gcttttttta cgctatccct tgaaaaaatg gtggaaagta
    90601 cgtgtcgaac gtgtaggtat cccgatgtta acagccatcc ccctactgac attaccgcaa
    90661 tttattatgc tgcaatacgt caaagggaaa gcggaaagtt ggcctgggct gtcaatgtat
    90721 gacaaatata atacgttggc ctgggaatta atatcgcacc tgtggttttt attggtgtta
    90781 gtggtcatga cgacgctgtg cgtctggata ttcaaacgca tcagaaataa tttagaaaat
    90841 tctgataaaa cgaataaaaa attctcgatg gtaaaactat cggtgatttt tttgtgcctc
    90901 ggcatcggtt atgcggtaat aagaagaacg atttttattg tgtatccgcc cattctgagt
    90961 aatggcatgt tcaattttat tgtcatgcaa acgctatttt atttgccgtt ctttatcctc
    91021 ggcgcactgg ctttcatttt ccctcatctt aaagccttgt ttaccacgcc gtctcgtggc
    91081 tgtaccctcg cagcagcatt ggcatttgtc gcttacttac tcaaccagcg ctatggcagt
    91141 ggcgatgcct ggatgtacga aaccgagtcg gtgatcacca tggtcctcgg tctgtggatg
    91201 gtgaatgtgg tcttctcctt cggccaccgt ttgcttaact tccagtcagc gcgggtgact
    91261 tactttgtta acgcatcgct gtttatctat ctggttcacc acccgttaac gctgtttttc
    91321 ggcgcataca ttacaccgca catcacctcc aactggcttg gttttctctg tggcctgata
    91381 ttcgttgtag ggattgcgat aattctgtat gaaattcatt tacgcatccc gttactgaag
    91441 tttttgttct ctggtaaacc ggttgtcaag cgtgagaacg ataaagcacc agcccgttaa
    91501 gccacgctta taataaccat tccacgggca atatcgatgc cagtctgacc ataacccgct
    91561 tccagaaact ggtggcgggt tcttttttga gaataatctc tttctttgca tgacgatcaa
    91621 cccagttgat ccgtccccac ctgtccagac ggagctgcca ggccgcatca tactggctct
    91681 gaataaagcg tttatcaatt aactgtgcca gcgtttcgct ctctatcacg aaccccattt
    91741 cagtattgag caatgtcgaa cgcggatcga aattgaaaga gccgataaac accgttttac
    91801 catcgatgct aaaggtttta gcatgcaggc tggcaccgga attaccggtt atgccgcgat
    91861 cgtgtaacgt actactttgt tcacgcgtcg gcttgagttc atataattcc acgccgtagc
    91921 ggagcaattt tttgcgccag cgtgcgtatc cggcatggac gacagcaaca tcgttagcgg
    91981 caagagaatt ggttaggatc gcaatcttta ccccttttct caccatccgt aagagttgcg
    92041 ccacacctgc gcgtgtcggt acaaaatagg cagagataat atcgatgcgt tcactgggtg
    92101 agcccatgat atcgaacagg cgctgcggta acagtgaatg ccgttttgcc ttgccctccc
    92161 ctttcgccgg atcatcactt aataaacgtg ttttcgccca gataagcggc aatgttccat
    92221 caaccagatg atttataaac ggactggatt ccattttgcg taagtaacga tgcgtcatag
    92281 catcgttatg ccaggaggcg ggtaactcga tgcgatccgc catttcacct tccgggacat
    92341 ccagcacctg ctgtaggggt gaaaccgatt tgcaatacca gtagcgggcg aaatcatcgg
    92401 caacgtcctc tacaactggt cctattgcca tgacatctaa atccgaaaaa agtggctctt
    92461 cccctgcacc aaaataggca tcaccaatat ttcgcccccc taccagcgtc accacgccat
    92521 cgacagtgaa acttttattg tgcatacggc gattgagacg ggaaaagtcg gtgatataac
    92581 caagcggacg tagcaagcga aacgagaaag gattaaaaag ccggacttca atgcggggat
    92641 gactgtcaag caagcgtaaa atgtcgtcaa gtccgggtgt attgttgtcg tccagcaaca
    92701 aacggacgcg aacgccacgc tttgctgcgg ctaacagggc ggaaaacagt aaccgacccg
    92761 acatatcgtc ctgccagatg taatactgaa catccagcgt atgctctgcc atttcggcca
    92821 gacgataccg ggcggcaaac gcatccagac ttttctccag agggaaaaga ccacactgac
    92881 cgggatgttg cgaacacagt ggcagcaccg cgctcgccag ccggggcaaa tcattcatct
    92941 ccttgttggg taaggagtct ttcgtagagg taggcgtttt cttcatcata acagacaaag
    93001 tatacctgtt cgggtaaagc gtgacgggta ataaattctg aaacggtttt tactgcgatt
    93061 tcagccgctg ccgcacgagg gtaaccataa accccagtac tgattgcagg aaaagccact
    93121 gacgtatagc tgtttgccgc caccagtcgt aggctattga gataggcatc ctgcaaaagc
    93181 tggtcttcgt tttgttcacc accacgccag actggcccga cggtgtgcac tacggcttta
    93241 gcgggaagat cgcctgcaag cgtaataacg gcatgccccg tagggcaatc gccctgctgt
    93301 tgcctgactt ttaaacaggc atccagcagc gccggacccg ctgcgcgatg aatggcccca
    93361 tcgacgccgc cgcctcccat taatgacgga ttagccgcat tcacaatcac atcaacggcc
    93421 agtttggtaa tatcaccctg cacaacatga atacgcgttt tcataacgcc tccttacacc
    93481 ttcttgtttc ttaagtgtac agcaggcttt ttggttaaat cgcatttttc tgctcagcaa
    93541 ggtgagttgt tcagaaactt agttatattc gatgttcatt acagccagct ttttctgttt
    93601 atcaagatac tgcactttta ctgaggctat ttgcgcgttt ttgacattgc cgctcattaa
    93661 cgctttgctg gaataggttc tgcccggaac agagccattc tgtgggcagt tcatttctac
    93721 gggtgatgac tgggtgctga cgtcacatgc cggttccaca atttggccat aaaagtggat
    93781 cacgccccct tgcgcgctgc ttcctgcgat ggcaataaaa ggaaaaaaca tactgccgag
    93841 cattagagag tctaaaaaag gtctgaacat ttattctatt tcctcaatga ttagtcatcc
    93901 ttgagggttg tgttatccat actttcaggt tggctgatcc gcagcagacc attctctcca
    93961 gattcatctt atgctcgata tttcaacaaa ttaagacttt tctgaagagg gcggccattg
    94021 ttgtgataaa tgaagtgact gtccatcaga aacagtaaca actattttca cccgatcgtc
    94081 cggggaaata tttaaactca acttcgtcaa agcaatgggt tgattagcag gcaatgagag
    94141 ggtcttttct tgcttcgtct gactttgccc tgaactgcct tcgcgcaggg acaatatttg
    94201 tactctgcac agacaagatt gagtaagagt gacttcagga ataatggtgt acatatcccc
    94261 ttgctgggtc gtattaaagg ttatctgact ggaaagtgcc gcaaggagta ataacgcatt
    94321 catattcttc tcccgaaaaa aaacagggct tgcgccctgt ttctttaata tagaggatgt
    94381 attagtactg atgagcggtc gcgttgttac caaagccaac ctgagtgacg ttaacgctgg
    94441 agttagatgc agtctggtca acagcagcac cgttaccgcc accgaactgt ttaacagtca
    94501 tagtagaatc tttaccattc cactgatcaa gagtagcgct gttgccgaaa ccacgctgag
    94561 tcagatcgat tgagctgtca tcagaacctt ggccaacatc tgcgccgtta ccgccgccgt
    94621 gctgggtaat ggtcagatca gagttacggg cgtcagcttg cagagcaaga gcagagttac
    94681 cgccaccgta ctggtaaatg ttcagctctg aatttgggcc gctattatta ccgccaccac
    94741 cgtggttacc gccgccgccg tactgaggaa caacacctgc cagagcgcta ccagagaata
    94801 cgattgctgc aattgctgct acttttaaaa gtttcatgta aaacccccat cggattgatt
    94861 taaaagtcga atggaaatta acgttgtgtc acgcgaatag ccatttgcga ctgtctctgc
    94921 actacaattg ccgttttttg agtaccatac tgtgtaatat ttgctttatt accagaacct
    94981 ttctggataa tcatcgcagt attaccataa gcaccttgcg aaatactggc atcgttggca
    95041 ttgcccgcct gatcaatata tgcaaggtta taatctcctg tctggtcaat ctttgcccgg
    95101 ttgctactac cttcttgcgc aacaaccgcc aaaagttttg agcctccctg ccgtaactga
    95161 gcactattat tagtcccagc ttgaccaatt atggctgcct gattaaatga agacttactc
    95221 aattcattta ccgcgaagtt atattctgaa ttagctaaat cataacctgc tgcggctgca
    95281 atcccaggcg cacccagtat tgttaacatc ataaataaca atttgttttt catgttgtca
    95341 ccctggacct ggtcgtacat ttaagaaatt aaatcatttc aacttggttg ttaacgcaac
    95401 ctgtattttg ttaacgctgc gttacgatgg aaa
//
LOCUS       DADXDL010000008        90235 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.008, whole genome shotgun sequence.
ACCESSION   DADXDL010000008 DADXDL010000000
VERSION     DADXDL010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 90235)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90235)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90235
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.008"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(106..1608)
                     /gene="araA"
                     /locus_tag="IRB70_000737"
     CDS             complement(106..1608)
                     /gene="araA"
                     /locus_tag="IRB70_000737"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBC0630686.1"
                     /translation="MTIFDNYEVWFVIGSQHLYGPETLRQVTQHAEHVVNALNTEAKL
                     PCKLVLKPLGTTPDEITAICRDANYDDRCAGLVVWLHTFSPAKMWINGLTMLNKPLLQ
                     FHTQFNAALPWDSIDMDFMNLNQTAHGGREFGFIGARMRQQHAVVTGHWQDKQAHERI
                     GSWMRQAVSKQDTRHLKVCRFGDNMREVAVTDGDKVAAQIKFGFSVNTWAVGDLVQVV
                     NSISDGDVNALVDEYESCYTMTPATQIHGKKRQNVLEAARIELGMKRFLEQGGFHAFT
                     TTFEDLHGLKQLPGLAVQRLMQQGYGFAGEGDWKTAALLRIMKVMSTGLQGGTSFMED
                     YTYHFEKGNDLVLGSHMLEVCPSIAAEEKPILDVQHLGIGGKDDPARLIFNTQTGPAI
                     VASLIDLGDRYRLLVNCIDTVKTPHSLPKLPVANALWKAQPDLPTASEAWILAGGAHH
                     TVFSHALNLNDMRQFAEMHDIEITVIDNDTRLPAFKDALRWNEVYYGFRR"
     gene            complement(1619..3319)
                     /gene="araB"
                     /locus_tag="IRB70_000738"
     CDS             complement(1619..3319)
                     /gene="araB"
                     /locus_tag="IRB70_000738"
                     /EC_number="2.7.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulokinase"
                     /protein_id="HBC0630687.1"
                     /translation="MAIAIGLDFGSDSVRALAVDCATGEEIATSVEWYPRWQKGQFCD
                     APNNQFRHHPRDYIESMEAALKTVLAELSVEQRAAVVGIGVDSTGSTPAPIDADGNVL
                     ALRPEFAENPNAMFVLWKDHTAVEEAEEITRLCHAPGNVDYSRYIGGIYSSEWFWAKI
                     LHVTRQDSAVAQSAASWIELCDWVPALLSGTTRPQDIRRGRCSAGHKSLWHESWGGLP
                     PASFFDELDPILNRHLPSPLFTDTWTADIPVGTLCPEWAQRLGLPESVVISGGAFDCH
                     MGAVGAGAQPNALVKVIGTSTCDILIADKQSVGERAVKGICGQVDGSVVPGFIGLEAG
                     QSAFGDIYAWFGRVLGWPLEQLAAQHPELKTQINASQKQLLPALTEAWAKNPSLDHLP
                     VVLDWFNGRRTPNANQRLKGVITDLNLATDAPLLFGGLIAATAFGARAIMECFTDQGI
                     AVNNVMALGGIARKNQVIMQACCDVLNRPLQIVASDQCCALGAAIFAAVAAKVHADIP
                     SAQQKMASAVEKTLQPCSEQAQRFEQLYRRYQQWAMSAEQHYLPTSAPAQAAQAVATL
                     "
     gene            3658..4536
                     /gene="araC"
                     /locus_tag="IRB70_000739"
     CDS             3658..4536
                     /gene="araC"
                     /locus_tag="IRB70_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose operon transcriptional regulator AraC"
                     /protein_id="HBC0630688.1"
                     /translation="MAEAQNDPLLPGYSFNAHLVAGLTPIEANGYLDFFIDRPLGMKG
                     YILNLTIRGQGVVKNQGREFVCRPGDILLFPPGEIHHYGRHPEAREWYHQWVYFRPRA
                     YWHEWLNWPSIFANTGFFRPDEAHQPHFSDLFGQIINAGQGEGRYSELLAINLLEQLL
                     LRRMEAINESLHPPMDNRVREACQYISDHLADSNFDIASVAQHVCLSPSRLSHLFRQQ
                     LGISVLSWREDQRISQAKLLLSTTRMPIATVGRNVGFDDQLYFSRVFKKCTGASPSEF
                     RAGCEEKVNDVAVKLS"
     gene            4622..5386
                     /locus_tag="IRB70_000740"
     CDS             4622..5386
                     /locus_tag="IRB70_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBC0630689.1"
                     /translation="MQALLEHFITQSTVYSLMAVVLVAFLESLALVGLILPGTVLMAG
                     LGALIGSGELSFWHAWLAGIIGCLMGDWISFWLGWRFKKPLHRWSFLKKNKALLDKTE
                     HALHQHSMFTILVGRFVGPTRPLVPMVAGMLDLPVAKFITPNIIGCLLWPPFYFLPGI
                     LAGAAIDIPAGMQSGEFKWLLLATAVFLWVGGWLCWRLWRSGKATDRLSHYLSRGRLL
                     WLTPLISAIGVVALVVLIRHPLMPVYIDILRKVVGV"
     gene            complement(5500..6198)
                     /gene="thiQ"
                     /locus_tag="IRB70_000741"
     CDS             complement(5500..6198)
                     /gene="thiQ"
                     /locus_tag="IRB70_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter ATP-binding protein
                     ThiQ"
                     /protein_id="HBC0630690.1"
                     /translation="MLKLTDITWLYHHLPMRFSLTVERGEQVAILGPSGAGKSTLLNL
                     IAGFLTPASGSLTIDGVDHTTMPPSRRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKL
                     NAVQQGKMHAIARQMGIDNLMARLPGELSGGQRQRVALARCLVREQPILLLDEPFSAL
                     DPALRQEMLTLVSTSCQQQKMTLLMVSHSVEDAARIATRSVVVADGRIAWQGMTNELL
                     SGKASASALLGITG"
     gene            complement(6182..7792)
                     /gene="thiP"
                     /locus_tag="IRB70_000742"
     CDS             complement(6182..7792)
                     /gene="thiP"
                     /locus_tag="IRB70_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine/thiamine pyrophosphate ABC transporter
                     permease ThiP"
                     /protein_id="HBC0630691.1"
                     /translation="MATRRQPLIPGWLIPGVSATTLVVAVALAAFLALWWNAPQDDWV
                     AVWQDSYLWHVVRFSFWQAFLSALLSVIPAIFLARALYRRRFPGRLALLRLCAMTLIL
                     PVLVAVFGILSVYGRQGWLATLCQSLGLEWTFSPYGLQGILLAHVFFNLPMASRLLLQ
                     ALENIPGEQRQLAAQLGMRSWHFFRFVEWPWLRRQIPPVAALIFMLCFASFATVLSLG
                     GGPQATTIELAIYQALSYDYDPARAAMLALLQMVCCLGLVLLSQRLSKAIAPGTTLLQ
                     GWRDPDDRLHSRICDTVLIVLALLLLLPPLLAVIVDGVNRQLPEVLAQPVLWQALWTS
                     LRIALAAGVLCVVLTMMLLWSSRELRARQKMLAGQVLEMSGMLILAMPGIVLATGFFL
                     LLNNTIGLPQSADGIVIFTNALMAIPYALKVLENPMRDITARYSMLCQSLGIEGWSRL
                     KVVELRALKRPLAQALAFACVLSIGDFGVVALFGNDDFRTLPFYLYQQIGSYRSQDGA
                     VTALILLLLCFLLFTVIEKLPGRNVKTD"
     gene            complement(7768..8751)
                     /gene="thiB"
                     /locus_tag="IRB70_000743"
     CDS             complement(7768..8751)
                     /gene="thiB"
                     /locus_tag="IRB70_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine ABC transporter substrate binding
                     subunit"
                     /protein_id="HBC0630692.1"
                     /translation="MLKKCLPLLLLCTAPVFAKPVLTVYTYDSFAADWGPGPVVKKAF
                     EADCNCELKLVALEDGVSLLNRLRMEGKNSKADVVLGLDNNLLDAASKTGLFAKSGVA
                     ADAVNVPGGWNNDTFVPFDYGYFAFVYDKNKLKNPPQSLKELVESDQNWRVIYQDPRT
                     STPGLGLLLWMQKVYGDDAPQAWQKLAKKTVTVTKGWSEAYGLFLKGESDLVLSYTTS
                     PAYHILEEKKDNYAAANFSEGHYLQVEVAARTAASKQPELAQKFLQFMVSPAFQNAIP
                     TGNWMYPVANVTLPAGFEKLTKPATTLEFTPAEVAAQRQAWISEWQRAVSR"
     regulatory      complement(8782..8881)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(8915..10570)
                     /gene="sgrR"
                     /locus_tag="IRB70_000744"
     CDS             complement(8915..10570)
                     /gene="sgrR"
                     /locus_tag="IRB70_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SgrR"
                     /protein_id="HBC0630693.1"
                     /translation="MPSARLQQQFIRLWQCCEGKSQDTTLNELAALLSCSRRHMRTLL
                     NTMQDRGWLTWEAEVGRGKRSRLTFLYTGLALQQQRAEDLLEQDRIDQLVQLVGDKAT
                     VRQMLVSHLGRSFRQGRHILRVLYYRPLRNLLPGSALRRSETHIARQIFSSLTRINEE
                     NGELEADIAHHWQQISPLHWRFFLRPGVHFHHGRELEMDDVIASLKRINTLPLYSHIA
                     DIVSPTPWTLDIHLTQPDRWLPLLLGQVPAMILPREWETLSNFASHPIGTGPYAVIRN
                     STNQLKIQAFDDFFGYRALIDEVNVWVLPEIADEPAGGLMLKGPQGEEKEIESRLEEG
                     CYYLLFDSRTHRGANQQVRDWVSYVLSPTNLVYFAEEQYQQLWFPAYGLLPRWHHART
                     IKSEKPAGLESLTLTFYQDHSEHRVIAGIMQQILASHQVTLKIKEIDYDQWHTGEIES
                     DIWLNSANFTLPLDFSVFAHLCEVPLLQHCIPIDWQADAARWRNGEMNLANWCQQLVA
                     SKAMVPLLHHWLIIQGQRSMRGLRMNTLGWFDFKSAWFAPPDP"
     gene            10659..10790
                     /gene="sgrT"
                     /locus_tag="IRB70_000745"
     CDS             10659..10790
                     /gene="sgrT"
                     /locus_tag="IRB70_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake inhibitor SgrT"
                     /protein_id="HBC0630694.1"
                     /translation="MRQFYQHYFTATAKLCWLRWLSVPQRLTMLEGLMQWDDRNSES"
     gene            10892..12070
                     /gene="setA"
                     /locus_tag="IRB70_000746"
     CDS             10892..12070
                     /gene="setA"
                     /locus_tag="IRB70_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetA"
                     /protein_id="HBC0630695.1"
                     /translation="MIWIMTMARRMNGVYAAFMLVAFMMGGAGALQAPTLSLFLSREV
                     GAQPFWIGLFYTVNAIAGIGVSLWLAKRSDSQGDRRKLIIFCCLMAIGNALLFAFNRH
                     YLTLITCGVLLASLANTAMPQLFALAREYADNSAREVVMFSSVMRAQLSLAWVIGPPL
                     AFMLALNYGFTVMFSIAAGIFTLSLVLIAFMLPSVARVELPSENALSMQGGWQDSNVR
                     MLFVASTLMWTCNTMYIIDMPLWISSELGLPDKLAGFLMGTAAGLEIPAMILAGYYVK
                     RYGKRRMMVIAVAAGVLFYTGLIFFNSRMALMTLQLFNAVFIGIVAGIGMLWFQDLMP
                     GRAGAATTLFTNSISTGVILAGVIQGAIAQSWGHFAVYWVIAVISVVALFLTAKVKDV
                     "
     gene            complement(12119..12724)
                     /gene="leuD"
                     /locus_tag="IRB70_000747"
     CDS             complement(12119..12724)
                     /gene="leuD"
                     /locus_tag="IRB70_000747"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase small subunit"
                     /protein_id="HBC0630696.1"
                     /translation="MAEKFIKHTGLVVPLDAANVDTDAIIPKQFLQKVTRTGFGAHLF
                     NDWRFLDEKGQQPNPDFVLNFPQYQGASILLARENFGCGSSREHAPWALTDYGFKVVI
                     APSFADIFYGNSFNNQLLPVKLSDAEVDELFALVKANPGIHFDVDLEAQEVKAGEKTY
                     RFTIDAFRRHCMMNGLDSIGLTLQHDDAIAAYEAKQPAFMN"
     gene            complement(12735..14135)
                     /gene="leuC"
                     /locus_tag="IRB70_000748"
     CDS             complement(12735..14135)
                     /gene="leuC"
                     /locus_tag="IRB70_000748"
                     /EC_number="4.2.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydratase large subunit"
                     /protein_id="HBC0630697.1"
                     /translation="MAKTLYEKLFDAHVVYEAENETPLLYIDRHLVHEVTSPQAFDGL
                     RAHGRPVRQPGKTFATMDHNVSTQTKDINACGEMARIQMQELIKNCKEFGVELYDLNH
                     PYQGIVHVMGPEQGVTLPGMTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLKQ
                     GRAKTMKIEVQGKAAPGITAKDIVLAIIGKTGSAGGTGHVVEFCGEAIRDLSMEGRMT
                     LCNMAIEMGAKAGLVAPDETTFNYVKGRLHAPKGKDFDDAVAYWKTLQTDEGATFDTV
                     VTLQAEEISPQVTWGTNPGQVISVNDNIPDPASFADPVERASAEKALAYMGLKPGIPL
                     TEVAIDKVFIGSCTNSRIEDLRAAAEIAKGRKVAPGVQALVVPGSGPVKAQAEAEGLD
                     KIFIEAGFEWRLPGCSMCLAMNNDRLNPGERCASTSNRNFEGRQGRGGRTHLVSPAMA
                     AAAAVTGHFADIRNIK"
     gene            complement(14138..15229)
                     /gene="leuB"
                     /locus_tag="IRB70_000749"
     CDS             complement(14138..15229)
                     /gene="leuB"
                     /locus_tag="IRB70_000749"
                     /EC_number="1.1.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-isopropylmalate dehydrogenase"
                     /protein_id="HBC0630698.1"
                     /translation="MSKNYHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYD
                     VGGAAIDNHGQPLPPATVEGCEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHF
                     KLFSNLRPAKLYQGLEAFCPLRADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEK
                     AFDTEVYHRFEIERIARIAFESARKRRHKVTSIDKANVLQSSILWREIVNEIATEYPD
                     VELAHMYIDNATMQLIKDPSQFDVLLCSNLFGDILSDECAMITGSMGMLPSASLNEQG
                     FGLYEPAGGSAPDIAGKNIANPIAQILSLALLLRYSLDADDAACAIERAINRALEEGI
                     RTGDLARGAAAVSTDEMGDIIARYVAEGV"
     gene            complement(15229..16800)
                     /gene="leuA"
                     /locus_tag="IRB70_000750"
     CDS             complement(15229..16800)
                     /gene="leuA"
                     /locus_tag="IRB70_000750"
                     /EC_number="2.3.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-isopropylmalate synthase"
                     /protein_id="HBC0630699.1"
                     /translation="MSQQVIIFDTTLRDGEQALQASLSVKEKLQIALALERMGVDVME
                     VGFPVSSPGDFESVQTIARQVKNSRVCALARCVEKDIDVAAESLKVAEAFRIHTFIAT
                     SPMHIATKLRSTLDEVIERAIYMVKRARNYTDDVEFSCEDAGRTPIADLARVVEAAIN
                     AGATTINIPDTVGYTMPFEFAGIISGLYERVPNIDKAIISVHTHDDLGLAVGNSLAAV
                     HAGARQVEGAMNGIGERAGNCSLEEVIMAIKVRKDILNVHTAINHQEIWRTSQLVSQI
                     CNMPIPANKAIVGSGAFAHSSGIHQDGVLKNRENYEIMTPESIGLNQIQLNLTSRSGR
                     AAVKHRMDEMGYKESEYNLDNLYDAFLKLADKKGQVFDYDLEALAFIGKQQEEPEHFR
                     LDYFSVQSGSNDIATAAVKLACGEEVKAEAANGNGPVDAVYQAINRITEYNVELVKYS
                     LTAKGHGKDALGQVDIVANYNGRRFHGVGLATDIVESSAKAMVHVLNNIWRAAEVEKE
                     LQRKAQHNENNKETV"
     gene            complement(16893..16979)
                     /gene="leuL"
                     /locus_tag="IRB70_000751"
     CDS             complement(16893..16979)
                     /gene="leuL"
                     /locus_tag="IRB70_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leu operon leader peptide"
                     /protein_id="HBC0630700.1"
                     /translation="MTHIVRFIGLLLLNASSLRGRRVSGIQH"
     gene            17639..18583
                     /gene="leuO"
                     /locus_tag="IRB70_000752"
     CDS             17639..18583
                     /gene="leuO"
                     /locus_tag="IRB70_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414618.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LeuO"
                     /protein_id="HBC0630701.1"
                     /translation="MPEVQTDHPETAELSKPQLRMVDLNLLTVFDAVMQEQNITRAAH
                     VLGMSQPAVSNAVARLKVMFNDELFVRYGRGIQPTARAFQLFGSVRQALQLVQNELPG
                     SGFEPASSERVFHLCVCSPLDSILTSQIYNHIEQIAPNIHVMFKSSLNQNTEHQLRYQ
                     ETEFVISYEDFHRPEFTSVPLFKDEMVLVASKNHPTIKGPLLKHDVYNEQHAAVSLDR
                     FASFSQPWYDTVDKQASIAYQGMAMMSVLSVVSQTHLVAIAPRWLAEEFAESLELQVL
                     PLPLKQNSRTCYLSWHEAAGRDKGHQWMEEQLVSICKR"
     gene            complement(18738..18782)
                     /locus_tag="IRB70_000753"
     CDS             complement(18738..18782)
                     /locus_tag="IRB70_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630702.1"
                     /translation="MKRNDKILHYRGLN"
     gene            18901..20625
                     /gene="ilvI"
                     /locus_tag="IRB70_000754"
     CDS             18901..20625
                     /gene="ilvI"
                     /locus_tag="IRB70_000754"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020079613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 3 large subunit"
                     /protein_id="HBC0630703.1"
                     /translation="MEMLSGAEMVVRSLIDQGVKQVFGYPGGAVLDIYDALHTVGGID
                     HVLVRHEQAAVHMADGLARATGEVGVVLVTSGPGATNAITGIATAYMDSIPLVVLSGQ
                     VATSLIGYDAFQECDMVGISRPVVKHSFLVKQTEDIPQVLKKAFWLAASGRPGPVVVD
                     LPKDILNPANKLPYVWPESVSMRSYNPTTTGHKGQIKRALQTLVAAKKPVVYVGGGAI
                     TAGCHQQLKETVEALNLPVVCSLMGLGAFPATHRQALGMLGMHGTYEANMTMHNADVI
                     FAVGVRFDDRTTNNLAKYCPNATVLHIDIDPTSISKTVTADIPIVGDARQVLEQMLEL
                     LSQESAHQPLDEIRDWWQQIEQWRARQCLKYDTHSEKIKPQAVIETLWRLTKGDAYVT
                     SDVGQHQMFAALYYPFDKPRRWINSGGLGTMGFGLPAALGVKMALPEETVVCVTGDGS
                     IQMNIQELSTALQYELPVLVVNLNNRYLGMVKQWQDMIYSGRHSQSYMQSLPDFVRLA
                     EAYGHVGIQISHPHELESKLSEALEQVRNNRLVFVDVTVDGSEHVYPMQIRGGGMDEM
                     WLSKTERT"
     gene            20628..21119
                     /gene="ilvN"
                     /locus_tag="IRB70_000755"
     CDS             20628..21119
                     /gene="ilvN"
                     /locus_tag="IRB70_000755"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001563086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HBC0630704.1"
                     /translation="MRRILSVLLENESGALSRVIGLFSQRGYNIESLTVAPTDDPTLS
                     RMTIQTVGDEKVLEQIEKQLHKLVDVLRVSELGQGAHVEREIMLVKIQASGYGRDEVK
                     RNTEIFRGQIIDVTPSLYTVQLAGTSGKLDAFLASIRDVAKIVEVARSGVVGLSRGDK
                     IMR"
     gene            21131..21217
                     /locus_tag="IRB70_000756"
     CDS             21131..21217
                     /locus_tag="IRB70_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fruR/shl operon leader peptide"
                     /protein_id="HBC0630705.1"
                     /translation="MRNLQPNMSRWAFFAKSVGTWNKSSCRS"
     gene            21299..22303
                     /gene="cra"
                     /locus_tag="IRB70_000757"
     CDS             21299..22303
                     /gene="cra"
                     /locus_tag="IRB70_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite repressor/activator"
                     /protein_id="HBC0630706.1"
                     /translation="MKLDEIARLAGVSRTTASYVINGKAKQYRVSDKTVEKVMAVVRE
                     HNYHPNAVAAGLRAGRTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQ
                     PDNEMRCIEHLLQRQVDAIIVSTSLPPEHPFYQRWANDPFPIVALDRALDREHFTSVV
                     GADQDDAEMLAEELRKFPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHFLYAN
                     SYEREAAAQLFEKWLETHPMPQALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDN
                     ELLDFLQCPVLAVAQRHRDVAERVLEIVLASLDEPRKPKPGLTRIKRNLYRRGVLSRS
                     "
     gene            22905..23363
                     /gene="mraZ"
                     /locus_tag="IRB70_000758"
     CDS             22905..23363
                     /gene="mraZ"
                     /locus_tag="IRB70_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020325403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBC0630707.1"
                     /translation="MFRGATLVNLDSKGRLSVPTRYREQLLENAAGQMVCTIDIYHPC
                     LLLYPLPEWEIIEQKLSRLSSMNPVERRVQRLLLGHASECQMDGAGRLLIAPVLRQHA
                     GLTKEVMLVGQFNKFELWDETTWHQQVKEDIDAEQLATGDLSERLQDLSL"
     gene            23365..24306
                     /gene="rsmH"
                     /locus_tag="IRB70_000759"
     CDS             23365..24306
                     /gene="rsmH"
                     /locus_tag="IRB70_000759"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBC0630708.1"
                     /translation="MMENYKHTTVLLDEAVNGLNIRPDGIYIDGTFGRGGHSRLILSQ
                     LGEEGRLLAIDRDPQAIAVAKTIDDPRFSIIHGPFSALGEYVAERDLIGKIDGILLDL
                     GVSSPQLDDAERGFSFMRDGPLDMRMDPTRGQSAAEWLQTAEEADIAWVLKTYGEERF
                     AKRIARAIVERNREQPMTRTKELAEVVAAATPVKDKFKHPATRTFQAVRIWVNSELEE
                     IEQALKSSLNVLAPGGRLSIISFHSLEDRIVKRFMRENSRGPQVPAGLPMTEEQLKKL
                     GGRQLRALGKLMPGEEEVAENPRARSSVLRIAERTNA"
     gene            24303..24668
                     /gene="ftsL"
                     /locus_tag="IRB70_000760"
     CDS             24303..24668
                     /gene="ftsL"
                     /locus_tag="IRB70_000760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000625658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBC0630709.1"
                     /translation="MISRVTEALSKVKGSMGSHERHALPGVIGDDLLRFGKLPLCLFI
                     CIILTAVTVVTTAHHTRLLTAQREQLVLERDALDIEWRNLILEENALGDHSRVERIAT
                     EKLQMQHVDPSQENIVVQK"
     gene            24684..26462
                     /gene="ftsI"
                     /locus_tag="IRB70_000761"
     CDS             24684..26462
                     /gene="ftsI"
                     /locus_tag="IRB70_000761"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000642204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase FtsI"
                     /protein_id="HBC0630710.1"
                     /translation="MKAAAKTQKPKRQEEHANFISWRFALLCGCILLALAFLLGRVAW
                     LQVISPDMLVKEGDMRSLRVQQVSTSRGMITDRSGRPLAVSVPVKAIWADPKEVHDAG
                     GISVGDRWKALANALNIPLDQLSARINANPKGRFIYLARQVNPDMADYIKKLKLPGIH
                     LREESRRYYPSGEVTAHLIGFTNVDSQGIEGVEKSFDKWLTGQPGERIVRKDRYGRVI
                     EDISSTDSHAAHNLALSIDERLQALVYRELNNAVAFNKAESGSAVLVDVNTGEVLAMA
                     NSPSYNPNNLSGTPKEAMRNRTITDVFEPGSTVKPMVVMTALQRGVVRENSVLNTIPY
                     RINYRINGHEIKDVARYSKLTLTGVLQKSSNVGVSKLALAMPSSALVDTYSRFGLGKA
                     TNLGLVGERSGLYPQKQRWSDIERATFSFGYGLMVTPLQLARVYATIGSYGIYRPLSI
                     TKVDPPVPGERVFPESIVRTVVHMMESVALPGGGGVKAAIKGYRIAIKTGTAKKVGPD
                     GRYINKYIAYTAGVAPASQPRFALVVVLNDPQAGKYYGGAVSAPVFGAIMGGVLRTMN
                     IEPDALTTGDKNEFVINQGEGTGGRS"
     gene            26449..27936
                     /gene="murE"
                     /locus_tag="IRB70_000762"
     CDS             26449..27936
                     /gene="murE"
                     /locus_tag="IRB70_000762"
                     /EC_number="6.3.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,
                     6-diaminopimelate ligase"
                     /protein_id="HBC0630711.1"
                     /translation="MADRNLRDLLAPWVPDAPSRALREMTLDSRVAAAGDLFVAVVGH
                     QADGRRYIPQAIAQGVAAIIAEAKDEATDGEIREMHGVPVIYLSQLNERLSALAGRFY
                     HEPSDNLRLVGVTGTNGKTTTTQLLAQWSQLLGETSAVMGTVGNGLLGKVIPTENTTG
                     SAVDVQHELAGLVDQGATFCAMEVSSHGLVQHRVTALKFAASVFTNLSRDHLDYHGDM
                     EHYEAAKWLLYSEHHCGQAIINADDEVGRRWLAKLPDAVAVSMEDHINPNCHGRWLKA
                     TEVNYHDSGATIRFSSSWGDGEIESHLMGAFNVSNLLLALATLLALGYPLADLLKTAA
                     RLQPVCGRMEVFTAPGKPTVVVDYAHTPDALEKALQAARLHCAGKLWCVFGCGGDRDK
                     GKRPLMGAIAEEFADVAVVTDDNPRTEEPRAIINDILAGMLDAGHAKVMEGRAEAVTC
                     AVMQAKENDVVLVAGKGHEDYQIVGNQRLDYSDRVTVARLLGVIA"
     gene            27933..29291
                     /gene="murF"
                     /locus_tag="IRB70_000763"
     CDS             27933..29291
                     /gene="murF"
                     /locus_tag="IRB70_000763"
                     /EC_number="6.3.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBC0630712.1"
                     /translation="MISVTLSQLTDILNGELKGADITLDAVTTDTRKLTPGCLFVALK
                     GERFDAHDFADQAKAGGAGALLVNRPLDIDLPQVIVKDTRLAFGELAAWVRQQVPARV
                     VALTGSSGKTSVKEMTAAILSQCGNTLYTAGNLNNDIGVPMTLLRLTPEYDYAVIELG
                     ANHQGEIAWTVSLTRPEAALVNNLAAAHLEGFGSLAGVAKAKGEIFSGLPENGIAIMN
                     ADNNDWLNWQSVIGSRKVWRFSPNAANSDFTATNIHVTSHGTEFTLQTPTGSVDVLLP
                     LPGRHNIANALAAAALSMSVGATLDAIKAGLANLKAVPGRLFPIQLAENQLLLDDSYN
                     ANVGSMTAAVQVLAEMPGYRVLVVGDMAELGAESEACHIQVGEAAKAAGIDRVLSVGK
                     QSHAISTASGVGEHFSDKTALIARLKSLIAEQQVITILVKGSRSAAMEEVVRALQENG
                     TC"
     gene            29285..30367
                     /gene="mraY"
                     /locus_tag="IRB70_000764"
     CDS             29285..30367
                     /gene="mraY"
                     /locus_tag="IRB70_000764"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBC0630713.1"
                     /translation="MLVWLAEHLVKYYSGFNVFSYLTFRAIVSLLTALFISLWMGPRM
                     IAHLQKLSFGQVVRNDGPESHFSKRGTPTMGGIMILTAIVISVLLWAYPSNPYVWCVL
                     VVLVGYGVIGFVDDYRKVVRKDTKGLIARWKYFWMSVIALGVAFALYLVGKDTPATQL
                     VVPFFKDVMPQLGLFYILLAYFVIVGTGNAVNLTDGLDGLAIMPTVFVAGGFALVAWA
                     TGNMNFASYLHIPYLRHAGELVIVCTAIVGAGLGFLWFNTYPAQVFMGDVGSLALGGA
                     LGIIAVLLRQEFLLVIMGGVFVVETLSVILQVGSFKLRGQRIFRMAPIHHHYELKGWP
                     EPRVIVRFWIISLMLVLIGLATLKVR"
     gene            30370..31686
                     /gene="murD"
                     /locus_tag="IRB70_000765"
     CDS             30370..31686
                     /gene="murD"
                     /locus_tag="IRB70_000765"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBC0630714.1"
                     /translation="MADYQGKNVVIIGLGLTGLSCVDFFLARGVTPRVMDTRMTPPGL
                     DKLPEAVERHTGGLNDEWLMAADLIVASPGIALAHPSLSAAADAGIEIVGDIELFCRE
                     AQAPIVAITGSNGKSTVTTLVGEMAKAAGVNVGVGGNIGLPALMLLDDECELYVLELS
                     SFQLETTSSLQAVAATILNVTEDHMDRYPFGLQQYRAAKLRIYENAKICVVNADDALT
                     MPIRGADERCVSFGVNMGDYHLNHQQGETWLRVKGEKVLNVKEMKLSGQHNYTNALAA
                     LALADAAGLPRASSLKALTTFTGLPHRFEVVLEHNGVRWINDSKATNVGSTEAALNGL
                     HVDGTLHLLLGGDGKSADFSPLARYLNGDNVRLYCFGRDGAQLAALRPEVAEQTETME
                     QAMRLLAPRVQPGDMVLLSPACASLDQFKNFEQRGNEFARLAKELG"
     gene            31686..32930
                     /gene="ftsW"
                     /locus_tag="IRB70_000766"
     CDS             31686..32930
                     /gene="ftsW"
                     /locus_tag="IRB70_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsW"
                     /protein_id="HBC0630715.1"
                     /translation="MRLSLPRLKMPRLPGFSILVWISTALKGWVMGSREKDTDSLIMY
                     DRTLLWLTFGLAAIGFIMVTSASMPIGQRLTNDPFFFAKRDGVYLILAFILAIITLRL
                     PMEFWQRYSATMLLGSIILLMIVLVVGSSVKGASRWIDLGLLRIQPAELTKLSLFCYI
                     ANYLVRKGDEVRNNLRGFLKPMGVILVLAVLLLAQPDLGTVVVLFVTTLAMLFLAGAK
                     LWQFIAIIGMGISAVVLLILAEPYRIRRVTAFWNPWEDPFGSGYQLTQSLMAFGRGEL
                     WGQGLGNSVQKLEYLPEAHTDFIFAIIGEELGYVGVVLALLMVFFVAFRAMSIGRKAL
                     EIDHRFSGFLACSIGIWFSFQALVNVGAAAGMLPTKGLTLPLISYGGSSLLIMSTAIM
                     MLLRIDYETRLEKAQAFVRGSR"
     gene            32927..33994
                     /gene="murG"
                     /locus_tag="IRB70_000767"
     CDS             32927..33994
                     /gene="murG"
                     /locus_tag="IRB70_000767"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBC0630716.1"
                     /translation="MSGQGKRLMVMAGGTGGHVFPGLAVAHHLMAQGWQVRWLGTADR
                     MEADLVPKHGIEIDFIRISGLRGKGIKALIAAPLRIFNAWRQARAIMKAYKPDVVLGM
                     GGYVSGPGGLAAWSLGIPVVLHEQNGIAGLTNKWLAKIATKVMQAFPGAFPNAEVVGN
                     PVRTDVLALPLPQQRLAGREGPVRVLVVGGSQGARILNQTMPQVAAKLGDSVTIWHQS
                     GKGSQQSVEQAYAEAGQPQHKVTEFIDDMAAAYAWADVVVCRSGALTVSEIAAAGLPA
                     LFVPFQHKDRQQYWNALPLEKAGAAKIIEQSQLSVDAVANTLAGWSRETLLTMAERAR
                     AASIPDATERVANEVSRAARA"
     gene            34048..35523
                     /gene="murC"
                     /locus_tag="IRB70_000768"
     CDS             34048..35523
                     /gene="murC"
                     /locus_tag="IRB70_000768"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBC0630717.1"
                     /translation="MNTQQLAKLRSIVPEMRRVRHIHFVGIGGAGMGGIAEVLANEGY
                     QISGSDLAPNPVTQQLMNLGATIYFNHRPENVRDASVVVVSSAISADNPEIVAAHEAR
                     IPVIRRAEMLAELMRFRHGIAIAGTHGKTTTTAMVSSIYAEAGLDPTFVNGGLVKAAG
                     VHARLGHGRYLIAEADESDASFLHLQPMVAIVTNIEADHMDTYQGDFENLKQTFINFL
                     HNLPFYGRAVMCVDDPVIRELLPRVGRQTTTYGFSEDADVRVEDYQQIGPQGHFTLLR
                     QDKEPMRVTLNAPGRHNALNAAAAVAVATEEGIDDEAILRALESFQGTGRRFDFLGEF
                     PLEPVNGKSGTAMLVDDYGHHPTEVDATIKAARAGWPDKNLVMLFQPHRFTRTRDLYD
                     DFANVLTQVDTLLMLEVYPAGEAPIPGADSRSLCRTIRGRGKIDPILVPDPAQVAEML
                     APVLTGNDLILVQGAGNIGKIARSLAEIKLKPQTPEEEQHD"
     gene            35516..36436
                     /gene="ddlB"
                     /locus_tag="IRB70_000769"
     CDS             35516..36436
                     /gene="ddlB"
                     /locus_tag="IRB70_000769"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBC0630718.1"
                     /translation="MTDKIAVLLGGTSAEREVSLNSGAAVLAGLREGGIDAYPVDPKE
                     VDVTQLKSMGFQKVFIALHGRGGEDGTLQGMLELMGLPYTGSGVMASALSMDKLRSKL
                     LWQGAGLPVAPWVALTRAEFEKGLSDKQLAEISALGLPVIVKPSREGSSVGMSKVVAE
                     NALQDALRLAFQHDEEVLIEKWLSGPEFTVAILGEEILPSIRIQPSGTFYDYEAKYLS
                     DETQYFCPAGLEASQEANLQALVLKAWTTLGCKGWGRIDVMLDSDGQFYLLEANTSPG
                     MTSHSLVPMAARQAGMSFSQLVVRILELAD"
     gene            36438..37268
                     /gene="ftsQ"
                     /locus_tag="IRB70_000770"
     CDS             36438..37268
                     /gene="ftsQ"
                     /locus_tag="IRB70_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ"
                     /protein_id="HBC0630719.1"
                     /translation="MSQAALNTRNSEEEVSSRRNNGTRLAGILFLLTVLTTVLVSGWV
                     VLGWMEDAQRLPLSKLVLTGERHYTRNDDIRQSILALGEPGTFMTQDVNIIQTQIEQR
                     LPWIKQVSVRKQWPDELKIHLVEYVPIARWNDQHMVDAEGNTFSVPPDRTSKQVLPML
                     YGPEGSANEVLQGYREMGQMLAKDRFTLKEAAMTARRSWQLTLNNDIKLNLGRGDTMK
                     RLARFVELYPVLQQQAQTDGKRISYVDLRYDSGAAVGWAPLPPEESTQQQNQAQAEQQ
                     "
     gene            37265..38527
                     /gene="ftsA"
                     /locus_tag="IRB70_000771"
     CDS             37265..38527
                     /gene="ftsA"
                     /locus_tag="IRB70_000771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBC0630720.1"
                     /translation="MIKATDRKLVVGLEIGTAKVAALVGEVLPDGMVNIIGVGSCPSR
                     GMDKGGVNDLESVVKCVQRAIDQAELMADCQISSVYLALSGKHISCQNEIGMVPISEE
                     EVTQEDVENVVHTAKSVRVRDEHRVLHVIPQEYAIDYQEGIKNPVGLSGVRMQAKVHL
                     ITCHNDMAKNIVKAVERCGLKVDQLIFAGLASSYSVLTEDERELGVCVVDIGGGTMDI
                     AVYTGGALRHTKVIPYAGNVVTSDIAYAFGTPPSDAEAIKVRHGCALGSIVGKDESVE
                     VPSVGGRPPRSLQRQTLAEVIEPRYTELLNLVNEEILQLQEKLRQQGVKHHLAAGIVL
                     TGGAAQIEGLAACAQRVFHTQVRIGAPLNITGLTDYAQEPYYSTAVGLLHYGKESHLN
                     GEAEVEKRVTASVGSWIKRLNSWLRKEF"
     gene            38588..39739
                     /gene="ftsZ"
                     /locus_tag="IRB70_000772"
     CDS             38588..39739
                     /gene="ftsZ"
                     /locus_tag="IRB70_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBC0630721.1"
                     /translation="MFEPMELTNDAVIKVIGVGGGGGNAVEHMVRERIEGVEFFAVNT
                     DAQALRKTAVGQTIQIGSGITKGLGAGANPEVGRNAADEDRDALRAALEGADMVFIAA
                     GMGGGTGTGAAPVVAEVAKDLGILTVAVVTKPFNFEGKKRMAFAEQGITELSKHVDSL
                     ITIPNDKLLKVLGRGISLLDAFGAANDVLKGAVQGIAELITRPGLMNVDFADVRTVMS
                     EMGYAMMGSGVASGEDRAEEAAEMAISSPLLEDIDLSGARGVLVNITAGFDLRLDEFE
                     TVGNTIRAFASDNATVVIGTSLDPDMNDELRVTVVATGIGMDKRPEITLVTNKQVQQP
                     VMDRYQQHGMAPLTQEQKPVAKVVNDNAPQTAKEPDYLDIPAFLRKQAD"
     gene            39840..40757
                     /gene="lpxC"
                     /locus_tag="IRB70_000773"
     CDS             39840..40757
                     /gene="lpxC"
                     /locus_tag="IRB70_000773"
                     /EC_number="3.5.1.108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-acyl-N-acetylglucosamine deacetylase"
                     /protein_id="HBC0630722.1"
                     /translation="MIKQRTLKRIVQATGVGLHTGKKVTLTLRPAPANTGVIYRRTDL
                     NPPVDFPADAKSVRDTMLCTCLVNEHDVRISTVEHLNAALAGLGIDNIVIEVNAPEIP
                     IMDGSAAPFVYLLLDAGIDELNCAKKFVRIKETVRVEDGDKWAEFKPYNGFSLDFTID
                     FNHPAIDSSNQRYAMNFSADAFMRQISRARTFGFMRDIEYLQSRGLCLGGSFDCAIVV
                     DDYRVLNEDGLRFEDEFVRHKMLDAIGDLFMCGHNIIGAFTAYKSGHALNNKLLQAVL
                     AKQEAWEYVTFQDDAELPLAFKAPSAVLA"
     gene            40987..41499
                     /gene="secM"
                     /locus_tag="IRB70_000774"
     CDS             40987..41499
                     /gene="secM"
                     /locus_tag="IRB70_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308128.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="secA regulator SecM"
                     /protein_id="HBC0630723.1"
                     /translation="MSGILTRWRQFGKRYFWPHLLLGMVAASLGLPALSNAAEPNAPA
                     KATTRNHEPSAKVNFGQLALLEANTRRPNSNYSVDYWHQHAIRTVIRHLSFAMAPQTL
                     PVAEESLPLQAQHLALLDTLSALLTQEGTPSEKGYRIDYAHFTPQAKFSTPVWISQAQ
                     GIRAGPQRLS"
     gene            41561..44266
                     /gene="secA"
                     /locus_tag="IRB70_000775"
     CDS             41561..44266
                     /gene="secA"
                     /locus_tag="IRB70_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBC0630724.1"
                     /translation="MLIKLLTKVFGSRNDRTLRRMRKVVNIINAMEPEMEKLSDEELK
                     GKTAEFRARLEKGEVLENLIPEAFAVVREASKRVFGMRHFDVQLLGGMVLNERCIAEM
                     RTGEGKTLTATLPAYLNALTGKGVHVVTVNDYLAQRDAENNRPLFEFLGLTVGINLPG
                     MPAPAKREAYAADITYGTNNEYGFDYLRDNMAFSPEERVQRKLHYALVDEVDSILIDE
                     ARTPLIISGPAEDSSEMYKRVNKIIPHLIRQEKEDSETFQGEGHFSVDEKSRQVNLTE
                     RGLVLIEELLVKEGIMDEGESLYSPANIMLMHHVTAALRAHALFTRDVDYIVKDGEVI
                     IVDEHTGRTMQGRRWSDGLHQAVEAKEGVQIQNENQTLASITFQNYFRLYEKLAGMTG
                     TADTEAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYMTEAEKIQAIIEDIKERTAKGQ
                     PVLVGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQAGYPAAVTIATNMAG
                     RGTDIVLGGSWQAEVAALENPTAEQIEKIKADWQVRHDAVLAAGGLHIIGTERHESRR
                     IDNQLRGRSGRQGDAGSSRFYLSMEDALMRIFASDRVSGMMRKLGMKPGEAIEHPWVT
                     KAIANAQRKVESRNFDIRKQLLEYDDVANDQRRAIYSQRNELLDVSDVSETINSIRED
                     VFKATIDAYIPPQSLEEMWDIPGLQERLKNDFDLDLPIAEWLDKEPELHEETLRERIL
                     AQSIEVYQRKEEVVGAEMMRHFEKGVMLQTLDSLWKEHLAAMDYLRQGIHLRGYAQKD
                     PKQEYKRESFSMFAAMLESLKYEVISTLSKVQVRMPEEVEELEQQRRMEAERLAQMQQ
                     LSHQDDDSAAAAALAAQTGERKVGRNDPCPCGSGKKYKQCHGRLQ"
     gene            44326..44715
                     /gene="mutT"
                     /locus_tag="IRB70_000776"
     CDS             44326..44715
                     /gene="mutT"
                     /locus_tag="IRB70_000776"
                     /EC_number="3.6.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="8-oxo-dGTP diphosphatase MutT"
                     /protein_id="HBC0630725.1"
                     /translation="MKKLQIAVGIIRNENNEIFITRRAADAHMANKLEFPGGKIEMSE
                     TPEQAVVRELQEEVGITPQHFSLFEKLEYEFPDRHITLWFWLVESWEGEPWGKEGQPG
                     EWMSLVGLNADDFPPANEPVLAKLKRL"
     gene            complement(44814..45011)
                     /gene="yacG"
                     /locus_tag="IRB70_000777"
     CDS             complement(44814..45011)
                     /gene="yacG"
                     /locus_tag="IRB70_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor YacG"
                     /protein_id="HBC0630726.1"
                     /translation="MSETITVNCPTCGKTVVWGEISPFRPFCSKRCQLIDLGEWAAEE
                     KRIPSSGDLSESDDWSEEPKQ"
     gene            complement(45021..45764)
                     /gene="zapD"
                     /locus_tag="IRB70_000778"
     CDS             complement(45021..45764)
                     /gene="zapD"
                     /locus_tag="IRB70_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapD"
                     /protein_id="HBC0630727.1"
                     /translation="MQTQVLFEHPLNEKMRTWLRIEFLIQQLTVNLPIVDHAGALHFF
                     RNVSELLDVFERGEVRTELLKELDRQQRKLQTWIGVPGVDQSRIEALIQQLKAAGSVL
                     ISAPRIGQFLREDRLIALVRQRLSIPGGCCSFDLPTLHIWLHLPQAQRDSQVETWIAS
                     LNPLTQALTMVLDLIRQSAPFRKQTSLNGFYQDNGGDADLLRLNLSLDSQLYPQISGH
                     KSRFAIRFMPLDSENGQVPERLDFELACC"
     gene            complement(45764..46384)
                     /gene="coaE"
                     /locus_tag="IRB70_000779"
     CDS             complement(45764..46384)
                     /gene="coaE"
                     /locus_tag="IRB70_000779"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBC0630728.1"
                     /translation="MRYIVALTGGIGSGKSTVANAFADLGINVIDADIIARQVVEPGA
                     PALHAIADHFGANIIAADGTLQRRALRERIFANPEEKNWLNALLHPLIQQETQHQIQQ
                     ATSPYVLWVVPLLVENSLYKKANRVLVVDVSPETQLKRTMQRDDVTREHVEQILAAQA
                     PREARLAVADDVIDNNGAPDAIASDVARLHAHYLQLASQFVSQEKP"
     gene            46409..46453
                     /locus_tag="IRB70_000780"
     CDS             46409..46453
                     /locus_tag="IRB70_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630729.1"
                     /translation="MIIKTLKMSARKRN"
     gene            46609..47652
                     /gene="guaC"
                     /locus_tag="IRB70_000781"
     CDS             46609..47652
                     /gene="guaC"
                     /locus_tag="IRB70_000781"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008461816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBC0630730.1"
                     /translation="MRIEEDLKLGFKDVLIRPKRSTLKSRSDVELERQFTFKHSGQSW
                     SGVPIIAANMDTVGTFSMASALASFDILTAVHKHYSVEEWQAFINNSSADVLKHVMVS
                     TGTSDADFEKTKQILDLNPALNFVCIDVANGYSEHFVQFVAKAREAWPTKTICAGNVV
                     TGEMCEELILSGADIVKVGIGPGSVCTTRVKTGVGYPQLSAVIECADAAHGLGGMIVS
                     DGGCTTPGDVAKAFGGGADFVMLGGMLAGHEESGGRIVEENGEKFMLFYGMSSESAMK
                     RHVGGVAEYRAAEGKTVKLPLRGPVENTARDILGGLRSACTYVGASRLKELTKRTTFI
                     RVLEQENRIFNNL"
     gene            complement(47687..48889)
                     /gene="hofC"
                     /locus_tag="IRB70_000782"
     CDS             complement(47687..48889)
                     /gene="hofC"
                     /locus_tag="IRB70_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein transport protein HofC"
                     /protein_id="HBC0630731.1"
                     /translation="MASKQLWRWHGITGDGNAQDGMLWAESRALLLIALQQQMVTPLS
                     LKRIAINSAQWRGDKSAEVIHQLATLLKAGLTLSEGLALLAEQHPSKQWQALLQSLAL
                     DLEQGIAFSNALLPWSEVFPPLYQAMIRTGELTGKLDECCFELARQQKAQRQLADKVK
                     SALRYPIIILAMAIMVVVAMLHFVLPEFAAIYKTFNTPLPALTQGIMTLASFSGEWGW
                     LLVLFGFLLAIANKLLMRHPTRLIARQKLLLRIPIMGSLMRGQKLTQIFTILALTQSA
                     GITFLQGVESVRETMRCPYWVQLLTQIQHDISNGHPIWLALKNTGEFSPLCLQLVRTG
                     EASGSLDLMLDNLAHHHRDNTLALADNLAALLEPALLIITGGIIGTLVVAMYLPIFHL
                     GDAMSGMG"
     gene            complement(48879..50264)
                     /gene="gspE"
                     /locus_tag="IRB70_000783"
     CDS             complement(48879..50264)
                     /gene="gspE"
                     /locus_tag="IRB70_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein GspE"
                     /protein_id="HBC0630732.1"
                     /translation="MNIPQLTALCLRYQGVLLDASEEVVHVAVVDAPSHELLDALHFA
                     TTKRIEITCWTRQQMEGHASRTQQTLPVAVQEKHQPKAELLTRTLQSALEQRASDIHI
                     EPADNAYRIRLRIDGVLHPLPDVSPDAGVALTARLKVLGNLDIAEHRLPQDGQFTVEL
                     AGNAVSFRIATLPCRGGEKVVLRLLQQVSQALDVNKLGMQPLQLADFAHALQQPQGLV
                     LVTGPTGSGKTVTLYSALQTLNTADINICSVEDPVEIPIAGLNQTQIHSRAGLTFQGV
                     LRALLRQDPDVIMIGEIRDGETAEIAIKAAQTGHLVLSTLHTNSTCETLVRLQQMGVA
                     RWMLSSALTLVIAQRLVRKLCPHCRRQQEEPIHIPDNVWPSPLPHWQAPGCVHCYHGF
                     YGRTALFEVLPITPIIRQLISANTDVESLETHARQAGMRTLFENGCLAVEQGLTTFEE
                     LIRVLGMPHGE"
     gene            complement(50274..50714)
                     /gene="ppdD"
                     /locus_tag="IRB70_000784"
     CDS             complement(50274..50714)
                     /gene="ppdD"
                     /locus_tag="IRB70_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent pilin"
                     /protein_id="HBC0630733.1"
                     /translation="MDKQRGFTLIELMVVIGIIAILSAIGIPAYQNYLRKAALTDMLQ
                     TFVPYRTAVELCALEHGGLNTCDGGSNGIPSPTTTRYVSAMSVAKGVVSLTGQESLNG
                     LSVVMTPGWDNANGVTGWTRNCNIQSDSALQQACEDVFRFDDAN"
     gene            complement(50917..51810)
                     /gene="nadC"
                     /locus_tag="IRB70_000785"
     CDS             complement(50917..51810)
                     /gene="nadC"
                     /locus_tag="IRB70_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxylating nicotinate-nucleotide
                     diphosphorylase"
                     /protein_id="HBC0630734.1"
                     /translation="MPPRRYNPDTRRDELLERINLDIPGAVAQALREDLGGTVDANND
                     ITAKLLPENSRSHATVITRENGVFCGKRWVEEVFIQLAGDDVTIIWHVDDGDVINANQ
                     PLFELEGPSRVLLTGERTALNFVQTLSGVASKVRHYVELLEGTNTQLLDTRKTLPGLR
                     SALKYAVLCGGGANHRLGLSDAFLIKENHIIASGSVRQAVEKASWLHPDAPVEVEVEN
                     LEELDEALKAGADIIMLDNFETEQMREAVKRTNGKALLEVSGNVTDKTLREFAETGVD
                     FISVGALTKHVQALDLSMRFC"
     gene            51898..52449
                     /gene="ampD"
                     /locus_tag="IRB70_000786"
     CDS             51898..52449
                     /gene="ampD"
                     /locus_tag="IRB70_000786"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,6-anhydro-N-acetylmuramyl-L-alanine amidase
                     AmpD"
                     /protein_id="HBC0630735.1"
                     /translation="MLLEQGWLAGARRVPSPHYDCRPDDETPTLLVVHNISLPPGEFG
                     GPWIDALFTGTIDPQAHPFFAEIAHLRVSAHCLIRRDGEIVQYVPFDKRAWHAGVSQY
                     QGRERCNDFSIGIELEGTDTLAYTDAQYQQLAAVTRALIDRYPDIANNMTGHCDIAPD
                     RKTDPGPAFDWARFRALISKETT"
     gene            52446..53300
                     /gene="ampE"
                     /locus_tag="IRB70_000787"
     CDS             52446..53300
                     /gene="ampE"
                     /locus_tag="IRB70_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase regulator AmpE"
                     /protein_id="HBC0630736.1"
                     /translation="MTLFTTLLVLIFERLFKLGEHWQLDHRLEAFFRRVKHFSLGRTL
                     GMTIIAMGVTFLLLRTLQGVLFNVPTLLVWLLIGLLCIGAGKVRLHYHAYLTAASRND
                     SHARATMAGELTMIHGVPAGCDEREYLRELQNALLWINFRFYLAPLFWLIVGGTWGPV
                     TLMGYAFLRAWQYWLARYQTPHHRLQSGIDAVLHVLDWVPVRLAGVVYALIGHGEKAL
                     PAWFASLGDFHTSQYQVLTRLAQFSLAREPHVDKVETPKAAVSMAKKTSFVVVVVIAL
                     LTIYGALV"
     gene            complement(53343..54716)
                     /gene="aroP"
                     /locus_tag="IRB70_000788"
     CDS             complement(53343..54716)
                     /gene="aroP"
                     /locus_tag="IRB70_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transporter AroP"
                     /protein_id="HBC0630737.1"
                     /translation="MMEGQQHGEQLKRGLKNRHIQLIALGGAIGTGLFLGSASVIQSA
                     GPGIILGYAIAGFIAFLIMRQLGEMVVEEPVAGSFSHFAYKYWGSFAGFASGWNYWVL
                     YVLVAMAELTAVGKYIQFWYPEIPTWVSAAVFFVVINAINLTNVKVFGEMEFWFAIIK
                     VIAVVAMIIFGGWLLFSGNGGPQATVSNLWDQGGFLPHGFTGLVMMMAIIMFSFGGLE
                     LVGITAAEADNPEQSIPKATNQVIYRILIFYIGSLAVLLSLMPWTRVTADTSPFVLIF
                     HELGDTFVANALNIVVLTAALSVYNSCVYCNSRMLFGLAQQGNAPKALASVDKRGVPV
                     NTILVSALVTALCVLINYLAPESAFGLLMALVVSALVINWAMISLAHMKFRRAKQEQG
                     VVTRFPALLYPLGNWICLLFMAAVLVIMLMTPGMAISVYLIPVWLIVLGIGYLFKEKT
                     AKAVKAH"
     gene            55257..56021
                     /gene="pdhR"
                     /locus_tag="IRB70_000789"
     CDS             55257..56021
                     /gene="pdhR"
                     /locus_tag="IRB70_000789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex transcriptional
                     repressor PdhR"
                     /protein_id="HBC0630738.1"
                     /translation="MAYSKIRQPKLSDVIEQQLEFLILEGTLRPGEKLPPERELAKQF
                     DVSRPSLREAIQRLEAKGLLLRRQGGGTFVQSSLWQSFSDPLVELLSDHPESQYDLLE
                     TRHALEGIAAYYAALRSTDEDKERIRELHHAIELAQQSGDLDAESNAVLQYQIAVTEA
                     AHNVVLLHLLRCMEPMLAQNVRQNFELLYSRREMLPLVSSHRTRIFEAIMAGKPEEAR
                     EASHRHLAFIEEILLDRSREESRRERSLRRLEQRKN"
     gene            56182..58845
                     /gene="aceE"
                     /locus_tag="IRB70_000790"
     CDS             56182..58845
                     /gene="aceE"
                     /locus_tag="IRB70_000790"
                     /EC_number="1.2.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008814576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring),
                     homodimeric type"
                     /protein_id="HBC0630739.1"
                     /translation="MSERFPNDVDPIETRDWLQAIESVIREEGVERAQYLIDQLLAEA
                     RKGGVNVAAGTGISNYINTIPVEEQPEYPGNLELERRIRSAIRWNAIMTVLRASKKDL
                     ELGGHMASFQSSATIYDVCFNHFFRARNEQDGGDLVYFQGHISPGVYARAFLEGRLTQ
                     EQLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLK
                     DTSKQTVYAFLGDGEMDEPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKII
                     NELEGIFEGAGWNVIKVMWGSRWDELLRKDTSGKLIQLMNETVDGDYQTFKSKDGAYV
                     REHFFGKYPETAALVADWTDEQIWALNRGGHDPKKIYAAFKKAQETKGKATVILAHTI
                     KGYGMGDAAEGKNIAHQVKKMNMDGVRHIRDRFNVPVSDADIEKLPYITFPEGSEEHT
                     YLHAQRQKLHGYLPSRQPNFTEKLELPSLQDFGALLEEQSKEISTTIAFVRALNVMLK
                     NKSIKDRLVPIIADEARTFGMEGLFRQIGIYSPNGQQYTPQDREQVAYYKEDEKGQIL
                     QEGINELGAGCSWLAAATSYSTNNLPMIPFYIYYSMFGFQRIGDLCWAAGDQQARGFL
                     IGGTSGRTTLNGEGLQHEDGHSHIQSLTIPNCISYDPAYAYEVAVIMHDGLERMYGEK
                     QENVYYYITTLNENYHMPAMPEGAEEGIRKGIYKLETIEGSKGKVQLLGSGSILRHVR
                     EAAEILAKDYGVGSDVYSVTSFTELARDGQDCERWNMLHPLETPRVPYIAQVMNDAPA
                     VASTDYMKLFAEQVRTYVPADDYRVLGTDGFGRSDSRENLRHHFEVDASYVVVAALGE
                     LAKRGEIDKKVVADAIAKFNIDADKVNPRLA"
     gene            58860..60752
                     /gene="aceF"
                     /locus_tag="IRB70_000791"
     CDS             58860..60752
                     /gene="aceF"
                     /locus_tag="IRB70_000791"
                     /EC_number="2.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase complex
                     dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBC0630740.1"
                     /translation="MAIEIKVPDIGADEVEITEILVKVGDKVEAEQSLITVEGDKASM
                     EVPSPQAGIVKEIKVSVGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAA
                     AAAKDVNVPDIGSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEI
                     KVNVGDKVSTGSLIMVFEVAGEAGAAAPAAKQEAAPAAASASAAGVKEVNVPDIGGDE
                     VEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIM
                     IFEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIR
                     RLAREFGVNLAKVKGTGRKGRILREDVQAYVKEAIKRAEAAPAVTGGGIPGMLPWPKV
                     DFSKFGEIEEVELGRIQKISGANLSRNWVMIPHVTHFDKTDITELEAFRKQQNEEAAK
                     RKLDVKITPVVFIMKAVAAALEQMPRFNSSLSEDGQRLTLKKYINIGVAVDTPNGLVV
                     PVFKDVNKKGIIELSRELMTISKKARDGKLTAGEMQGGCFTISSIGGLGTTHFAPIVN
                     APEVAILGVSKSAMEPVWNGKEFVPRLMLPISLSFDHRVIDGADGARFITIINNTLSD
                     IRRLVM"
     gene            60960..62384
                     /gene="lpdA"
                     /locus_tag="IRB70_000792"
     CDS             60960..62384
                     /gene="lpdA"
                     /locus_tag="IRB70_000792"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBC0630741.1"
                     /translation="MSTEIKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGV
                     CLNVGCIPSKALLHVAKVIEEAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLA
                     GMAKGRKVKVVNGLGKFTGANTLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDP
                     RIWDSTDALELKEVPERLLVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDI
                     VKVFTKRISKKFNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVLVAIGRVPN
                     GKNLDAGKAGVEVDDRGFIRVDKQLRTNVPHIFAIGDIVGQPMLAHKGVHEGHVAAEV
                     IAGKKHYFDPKVIPSIAYTEPEVAWVGLTEKEAKEKGISYETATFPWAASGRAIASDC
                     ADGMTKLIFDKESHRVIGGAIVGTNGGELLGEIGLAIEMGCDAEDIALTIHAHPTLHE
                     SVGLAAEVFEGSITDLPNPKAKKK"
     gene            complement(62455..64308)
                     /locus_tag="IRB70_000793"
     CDS             complement(62455..64308)
                     /locus_tag="IRB70_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3300 domain-containing protein"
                     /protein_id="HBC0630742.1"
                     /translation="MKMTLPFKPHVLALICSAGLCAASAGLYIKSRTVEAPVEAQSTQ
                     LAVSDAAAVTLPATVSVPPVTPAVVKSAFSTAQIDQWVAPVALYPDSLLSQVLMASTY
                     PANVAQAVQWSHDNPLKQGDAAIQAVSDQPWDASVKSLVAFPQLMALMGENPQWVQNL
                     GDAFLAQPQDVMDSVQRLRQLAQQTGSLKSSTEQKVITTTKKAVPVTQTVTAPVIPSN
                     TVSTANPVITEPATTVISIEPTNPDVVYIPNYNPTVVYGNWANTAYPPVYLPPPAGEP
                     FVDSFVRGFGYSMGVATTYALFSSIDWDDDDHDHHHHDDDDYHHHDGGHRDGNDWQHN
                     GDNINIDVNNFNRITGEHLTDKNMAWRHNPNYRDGVPYHDQDMAKRFHQTDVNGGMSA
                     TQLPALSRDSQRQAAASQFQQRTHAAPVTTRDTQRQAAAQRFNEAENYGSYDDFRDFS
                     RRQPLTQQQKDAARQRYQSASPEQRQAVREKMQTNPQIQQRREAARERIQSASPEQRQ
                     AVREKMQTNPQNQQRREAARQRIQSATPEQRQVFKEKVQQRPLNQQQRDNARQRIQSA
                     SPEQRQVFREKVQESRPQRLNDSNHTVRLNNEQRSAVRERLSERGARRLER"
     gene            64663..67260
                     /gene="acnB"
                     /locus_tag="IRB70_000794"
     CDS             64663..67260
                     /gene="acnB"
                     /locus_tag="IRB70_000794"
                     /EC_number="4.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aconitate hydratase
                     2/2-methylisocitrate dehydratase"
                     /protein_id="HBC0630743.1"
                     /translation="MLEEYRKHVAERAAEGIAPKPLDANQMAALVELLKNPPAGEEEF
                     LLDLLTNRVPPGVDEAAYVKAGFLAAVAKGEAKSPLLTPEKAIELLGTMQGGYNIHPL
                     IDALDDAKLAPIAAKALSHTLLMFDNFYDVEEKAKAGNEYAKQVMQSWADAEWFLNRP
                     ALAEKLTVTVFKVTGETNTDDLSPAPDAWSRPDIPLHALAMLKNAREGIEPDQPGVVG
                     PIKQIEALQQKGFPLAYVGDVVGTGSSRKSATNSVLWFMGDDIPHVPNKRGGGLCLGG
                     KIAPIFFNTMEDAGALPIEVDVSNLNMGDVIDVYPYKGEVRNHETGELLATFELKTDV
                     LIDEVRAGGRIPLIIGRGLTTKAREALGLPHSDVFRQAKDVAESDRGFSLAQKMVGRA
                     CGVKGIRPGAYCEPKMTSVGSQDTTGPMTRDELKDLACLGFSADLVMQSFCHTAAYPK
                     PVDVNTHHTLPDFIMNRGGVSLRPGDGVIHSWLNRMLLPDTVGTGGDSHTRFPIGISF
                     PAGSGLVAFAAATGVMPLDMPESVLVRFKGKMQPGITLRDLVHAIPLYAIKQGLLTVE
                     KKGKKNIFSGRILEIEGLPDLKVEQAFELTDASAERSAAGCTIKLNKEPIIEYLNSNI
                     VLLKWMIAEGYGDRRTLERRIQGMEKWLANPELLEADADAEYAAVIDIDLADIKEPIL
                     CAPNDPDDARPLSAVQGEKIDEVFIGSCMTNIGHFRAAGKLLDAHKGQLPTRLWVAPP
                     TRMDAAQLTEEGYYSVFGKSGARIEIPGCSLCMGNQARVADGATVVSTSTRNFPNRLG
                     TGANVFLASAELAAVAALIGKLPTPEEYQTYVAQVDKTAVDTYRYLNFNQLSQYTEKA
                     DGVIFQTAV"
     gene            67436..67798
                     /locus_tag="IRB70_000795"
     CDS             67436..67798
                     /locus_tag="IRB70_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414661.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacL family protein"
                     /protein_id="HBC0630744.1"
                     /translation="MDYEFLRDITGVVKVRMSMGHEVVGHWFNEEVKENLALLDEVEQ
                     AAHALKGSERSWQRAGHEYTLWMDGEEVMVRANQLEFAGDEMEEGMNYYDEESLSLCG
                     VEDFLQVVAAYRNFVQQK"
     gene            complement(67836..68630)
                     /gene="speD"
                     /locus_tag="IRB70_000796"
     CDS             complement(67836..68630)
                     /gene="speD"
                     /locus_tag="IRB70_000796"
                     /EC_number="4.1.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylmethionine decarboxylase"
                     /protein_id="HBC0630745.1"
                     /translation="MKKLKLHGFNNLTKSLSFCIYDICYAKTTEERDGYIAYIDELYN
                     ANRLTEILSETCSIIGANILNIARQDYEPQGASVTILVSEEPVDPKLIDKTEHPGPLP
                     ETVVAHLDKSHICVHTYPESHPEGGLCTFRADIEVSTCGVISPLKALNYLIHQLESDI
                     VTIDYRVRGFTRDINGMKHFIDHEINSIQNFMSDDMKALYDMVDVNVYQENIFHTKML
                     LKEFDFKHYMFHTKPEDLTDSERQEITAALWKEMREIYYGRNMPAV"
     gene            complement(68646..69512)
                     /gene="speE"
                     /locus_tag="IRB70_000797"
     CDS             complement(68646..69512)
                     /gene="speE"
                     /locus_tag="IRB70_000797"
                     /EC_number="2.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyamine aminopropyltransferase"
                     /protein_id="HBC0630746.1"
                     /translation="MAEKKQWHETLHDQFGQYFAVDNVLYHEKTDHQDLIIFENAAFG
                     RVMALDGVVQTTERDEFIYHEMMTHVPLLAHGHAKHVLIIGGGDGAMLREVTRHKNVE
                     SITMVEIDAGVVSFCRQYLPNHNAGSYDDPRFKLVIDDGVNFVNQTSQTFDVIISDCT
                     DPIGPGESLFTSAFYEGCKRCLNPGGIFVAQNGVCFLQQEEAIDSHRKLSHYFSDVGF
                     YQAAIPTYYGGIMTFAWATDNDALRHLSTEIIQARFLASGLKCRYYNPAVHTAAFALP
                     QYLQDALASQPS"
     gene            complement(69618..69965)
                     /locus_tag="IRB70_000798"
     CDS             complement(69618..69965)
                     /locus_tag="IRB70_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414664.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YacC family pilotin-like protein"
                     /protein_id="HBC0630747.1"
                     /translation="MKTFFRTVLFGSLMAVCANSYALSESEAEDMADLTAVFVFLKND
                     CGYQNLPNGQIRRALVFFAQQNQWDLSNYDTFDMKALGEDSYRDLSGIGIPVAKKCKA
                     LARDSLSLLAYVK"
     gene            70131..71681
                     /gene="cueO"
                     /locus_tag="IRB70_000799"
     CDS             70131..71681
                     /gene="cueO"
                     /locus_tag="IRB70_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multicopper oxidase CueO"
                     /protein_id="HBC0630748.1"
                     /translation="MQRRDFLKYSVALGVASALPLWSRAVFAAERPTLPIPDLLTTDA
                     RNRIQLTIGAGQSTFGGKTATTWGYNGNLLGPAVKLQRGKAVTVDIYNQLTEETTLHW
                     HGLEVPGEVDGGPQGIIPPGGKRSVTLNVDQPAATCWFHPHQHGKTGRQVAMGLAGLV
                     VIEDDEILKLMLPKQWGIDDVPVIVQDKKFSADGQIDYQLDVMTAAVGWFGDTLLTNG
                     VIYPQHAAPRGWLRLRLLNGCNARSLNFATSDNRPLYVIASDGGLLPEPVKVNELPVL
                     MGERFEVLVEVNDNKPFDLVTLPVSQMGMAIAPFDKPHPVMRIQPIAISASGTLPDTL
                     SSLPALPSLEGLTVRKLQLSMDPMLDMMGMQMLMEKYGDQAMAGMDHSQMMGHMGHGN
                     MNHMNHGGKFDFHHANKINGQAFDMNKPMFAAAKGQYERWVISGVGDMMLHPFHIHGT
                     QFRILSENGKPPATHRAGWKDTVKVEGNVSEVLVKFNHDAPKEHAYMAHCHLLEHEDT
                     GMMLGFTV"
     gene            complement(71728..74118)
                     /gene="gcd"
                     /locus_tag="IRB70_000800"
     CDS             complement(71728..74118)
                     /gene="gcd"
                     /locus_tag="IRB70_000800"
                     /EC_number="1.1.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinoprotein glucose dehydrogenase"
                     /protein_id="HBC0630749.1"
                     /translation="MAINNTGSRRLLVTLTALFAALCGLYLLIGGGWLVAIGGSWYYP
                     IAGLVMLGVAWMLWRSKRAALWLYAALLLGTMIWGVWEVGFDFWALTPRSDILVFFGI
                     WLILPFVWRRLVIPASGAVAALVVALLISGGILTWAGFNDPQEINGTLSADATPAEAI
                     SPVADQDWPAYGRNQEGQRFSPLKQINADNVHNLKEAWVFRTGDVKQPNDPGEITNEV
                     TPIKVGDTLYLCTAHQRLFALDAASGKEKWHYDPELKTNESFQHVTCRGVSYHEAKAE
                     TASPEVMADCPRRIILPVNDGRLIAINAENGKLCETFANKGVLNLQSNMPDTKPGLYE
                     PTSPPIITDKTIVMAGSVTDNFSTRETSGVIRGFDVNTGELLWAFDPGAKDPNAIPSD
                     EHTFTFNSPNSWAPAAYDAKLNLVYLPMGVTTPDIWGGNRTPEQERYASSILALNATT
                     GKLAWSYQTVHHDLWDMDLPAQPTLADITVNGQKVPVIYAPAKTGNIFVLDRRNGELV
                     VPAPEKPVPQGAAKGDYVTPTQPFSELSFRPTKDLSGADMWGATMFDQLVCRVMFHQM
                     RYEGIFTPPSEQGTLVFPGNLGMFEWGGISVDPNREVAIANPMALPFVSKLIPRGPGN
                     PMEQPKDAKGTGTESGIQPQYGVPYGVTLNPFLSPFGLPCKQPAWGYISALDLKTNEV
                     VWKKRIGTPQDSMPFPMPVPVPFNMGMPMLGGPISTAGNVLFIAATADNYLRAYNMSN
                     GEKLWQGRLPAGGQATPMTYEVNGKQYVVISAGGHGSFGTKMGDYIVAYALPDDVK"
     gene            74324..74860
                     /gene="hpt"
                     /locus_tag="IRB70_000801"
     CDS             74324..74860
                     /gene="hpt"
                     /locus_tag="IRB70_000801"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004204384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBC0630750.1"
                     /translation="MKHTVEVMIPEAEIKARIAELGRQITERYKDSGSDMVLVGLLRG
                     SFMFMADLCREVQVSHEVDFMTASSYGSGMSTTRDVKILKDLDEDIRGKDVLIVEDII
                     DSGNTLSKVREILSLREPKSLAICTLLDKPSRREVNVPVEFIGFSIPDEFVVGYGIDY
                     AQRYRHLPYIGKVILLDE"
     gene            complement(74901..75563)
                     /gene="can"
                     /locus_tag="IRB70_000802"
     CDS             complement(74901..75563)
                     /gene="can"
                     /locus_tag="IRB70_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonate dehydratase"
                     /protein_id="HBC0630751.1"
                     /translation="MKDIDTLISNNALWSKMLVEEDPGFFEKLAQAQKPRFLWIGCSD
                     SRVPAERLTGLEPGELFVHRNVANLVIHTDLNCLSVVQYAVDVLEVEHIIICGHYGCG
                     GVQAAVENPELGLINNWLLHIRDIWFKHSSLLGEMPQERRLDTLCELNVMEQVYNLGH
                     STIMQSAWKRGQKVTIHGWAYGIHDGLLRDLDVTATNRETLEQRYRHGISNLKLKHAN
                     HK"
     gene            75672..76598
                     /locus_tag="IRB70_000803"
     CDS             75672..76598
                     /locus_tag="IRB70_000803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0630752.1"
                     /translation="MTIALELQQLKKTYPGGVQALRGIDLQVEAGDFYALLGPNGAGK
                     STTIGIISSLVNKTSGRVSVFGYDLEKDVVNAKRQLGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVERKEAYIRSEKYLKQLDLWGKRNERARMLSGGMKRRLMIARALMHEPKLLIL
                     DEPTAGVDIELRRSMWGFLKDLNDKGTTIILTTHYLEEAEMLCRNIGIIQHGELVENT
                     SMKALLAKLKSETFILDLAPKSPLPKLDGYQYRLVDTATLEVEVLREQGINSVFTQLS
                     EQGIQVLSMRNKANRLEELFVSLVNEKQGDRA"
     gene            76595..77365
                     /locus_tag="IRB70_000804"
     CDS             76595..77365
                     /locus_tag="IRB70_000804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0630753.1"
                     /translation="MMHLYWVALKSIWAKEIHRFMRIWVQTLVPPVITMTLYFIIFGN
                     LIGSRIGDMHGFSYMQFIVPGLIMMSVITNAYANVASSFFGAKFQRNIEELLVAPVPT
                     HVIIAGYVGGGVARGLFVGILVTAISLFFVPFQVHSWVFVALTLVLTAVLFSLAGLLN
                     GVFAKTFDDISLVPTFVLTPLTYLGGVFYSLTLLPPFWQGLSHLNPIVYMISGFRYGF
                     LGINDVPLVTTFGVLVVFIVAFYLICWSLIQRGRGLRS"
     gene            77470..77910
                     /locus_tag="IRB70_000805"
     CDS             77470..77910
                     /locus_tag="IRB70_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBC0630754.1"
                     /translation="MLGWVITCHDDRAQEILDALEKKHGALLQCRAVNFWRGLSSNML
                     SRMMCDALHEADSGEGVIFLTDIAGAPPYRVASLLSHKHSRCEVISGVTLPLIEQMLA
                     YRETLSSAEFRERIVELGAPEVSSLWHQQQKNPPFVLKHNLYEY"
     gene            77974..79203
                     /locus_tag="IRB70_000806"
     CDS             77974..79203
                     /locus_tag="IRB70_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBC0630755.1"
                     /translation="MYKQAVILLLMLFTASVSAALPARYMQTIENAAVWAQIGDKMVT
                     VGNIRAGQIIAVEPTAASYYAFNFGFGKGFIDKGHLEPVQGRQKVEDGLGDLNKPLSN
                     QNLITWKDTPVYNAPSVGSAPFGVLADNLRYPILHKLKDRLNQTWYQIRIGDRLAYIS
                     ALDAQPDNGLPVLTYHHILRDEENTRFRHTSTTTSVRAFNNQMAWLRDRGYATLSMAQ
                     LEGYVKNKINLPARAVVITFDDGLKSVSRYAYPVLKQYGMKATAFIVTSRIKRHPQKW
                     NPKSLQFMSVSELNEIRDVFDFQSHTHFLHRIDGYRRPILLSRSEHNILFDFARSRRA
                     LAQFNPHVLYLSYPFGGFNDKAVKAAKEAGFHLAVTTMKGKVKPGDNPLLLKRLYILR
                     TDSLETMSRLVSNQPQG"
     gene            complement(79207..79587)
                     /gene="panD"
                     /locus_tag="IRB70_000807"
     CDS             complement(79207..79587)
                     /gene="panD"
                     /locus_tag="IRB70_000807"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HBC0630756.1"
                     /translation="MIRTMLQGKLHRVKVTHADLHYEGSCAIDQDFLDAAGILENEAI
                     DIWNVTNGKRFSTYAIAAERGSRIISVNGAAAHCASVGDIVIIASFVTMPDEEARTWR
                     PNVAYFEGDNEMKRTAKAIPVQVA"
     gene            79861..80793
                     /locus_tag="IRB70_000808"
     CDS             79861..80793
                     /locus_tag="IRB70_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBC0630757.1"
                     /translation="MDAPSTTPHDAVFKQFLMHAETARDFLDIHLPAELRELCDLDTL
                     HLESGSFIEESLKGHSTDVLYSVQMQGNTGYLHVVIEHQSKPDKKMAFRMMRYSIAAM
                     HRHLEADHDKLPLVVPILFYQGEATPYPLSMCWFDMFYSPELARRVYNSPFPLVDITI
                     TPDDEIMQHRRIAILELLQKHIRQRDLMLLLEQLVTLIDEGYTSGSQLVAMQNYMLQR
                     GHTEQADLFYGVLRDRETGGESMMTLAQWFEERGRQEERQEVRQEVRQEVIQEVRQEV
                     RQEFALRFLSKGMSREDVAEMANLPLAEVDKLIS"
     gene            80862..81065
                     /locus_tag="IRB70_000809"
     CDS             80862..81065
                     /locus_tag="IRB70_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000404125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0630758.1"
                     /translation="MEIKTRRETRQTLAQWFEEKEFQKGYKEGLQKVRLAQRLLSKGM
                     SREDVAEVTALSLAEIDKLINSN"
     gene            complement(81147..81998)
                     /gene="panC"
                     /locus_tag="IRB70_000810"
     CDS             complement(81147..81998)
                     /gene="panC"
                     /locus_tag="IRB70_000810"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBC0630759.1"
                     /translation="MLIIETLPLLRQQIRRLRMEGKRVALVPTMGNLHDGHMKLVDEA
                     KARADVVVVSIFVNPMQFDRPEDLARYPRTLQEDCEKLNKRKVDLVFAPSVKEIYPNG
                     TETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPDIACFGEKDFQQLALIR
                     KMVADMGFDIEIIGVPIMRAKDGLALSSRNGYLTAEQRKIAPGLYKVLSSIADKLQAG
                     ERDLDEIITIAGQELNEKGFRADDIQIRDADTLLEISENSKRAVILVAAWLGDARLID
                     NKIVELA"
     gene            complement(82010..82804)
                     /gene="panB"
                     /locus_tag="IRB70_000811"
     CDS             complement(82010..82804)
                     /gene="panB"
                     /locus_tag="IRB70_000811"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000805487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBC0630760.1"
                     /translation="MKPTTIASLQKCKQDKKRFATITAYDYSFAKLFAEEGLNVMLVG
                     DSLGMTVQGHDSTLPVTVADIAYHTAAVRRGAPNCLLLADLPFMAYATPEQAFENAAT
                     VMRAGANMVKIEGGEWLVETVQMLTERAVPVCGHLGLTPQSVNIFGGYKVQGRGDEAG
                     DQLLSDALALEAAGAQLLVLECVPVELAKRITEALAIPVIGIGAGNVTDGQILVMHDA
                     FGITGGHIPKFAKNFLAETGDIRAAVRQYMAEVESGVYPGEEHSFH"
     gene            complement(82916..84187)
                     /locus_tag="IRB70_000812"
     CDS             complement(82916..84187)
                     /locus_tag="IRB70_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000848455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like adhesin"
                     /protein_id="HBC0630761.1"
                     /translation="MKTFFRYFLFLILCLSCYTASAGTDDFVGYVVGNNYGVGPSDQK
                     WRETGPNGDVTVVFRYGTSTNNLVFYKPTQLGPTGVKLHWSQLDTASGGGFLYCNRSN
                     NTSGGAMRIENAMVDSGKRYGNHKLFNTSVPGLYYTILISNMWSAYGTVTNVSSPGIY
                     IGDSAEQYFSWYNPSESILYQSCNNANTSSKYWAVGGIYQNLTIEFYTDTNFDPTVTQ
                     QVSLSRSSNYLYSFKAYGAGIGINEHSYFLRVDFDLLNIKLSNPTCFTAILSGTSVTG
                     STVKMGEYSEAQIRNGATPVPFDISLQNCVRVTNIETKLVSTKVGTENRQLLGNTLTG
                     SGAAKGVGVLIEGLANSKSALMILKPNDSTSVYKDNTGQTQNNDSDAIYPEDDGITYP
                     LHFQATLKQDGNIAIEPGDFKATSTFQVTYP"
     gene            complement(84241..84837)
                     /locus_tag="IRB70_000813"
     CDS             complement(84241..84837)
                     /locus_tag="IRB70_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630762.1"
                     /translation="MLSSQLKIKIKTSLFLALLFATSSPVYAGLDVDMVANIKNSTCK
                     SGLSNLGNIDLGVVGVDYFSGNVAPEDDYPGGREFTITVTDCAIQGSGNVLNQLHINF
                     KPLNGVMATGSQQIFANENVAGAQNVGVVIFSTQDPANIFNVLTPAGSSRSIYPVMTA
                     DLNNSSWKFYTRMQKINPVLNVMPGQIISHVLIDIYYE"
     gene            complement(84864..85469)
                     /gene="yadL"
                     /locus_tag="IRB70_000814"
     CDS             complement(84864..85469)
                     /gene="yadL"
                     /locus_tag="IRB70_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000837848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial-like protein YadL"
                     /protein_id="HBC0630763.1"
                     /translation="MKSKTLCYGLPAGVFFAASLFTSQLFAATDSVKLNVKATVETGT
                     CTASLVDDNDQPISVIAFGDAYIPEIDAKTKIKIFKLQFKDCAGIPNKKALVKLTKRA
                     TCEGAANDGPGFANGSAAADKANAVAVEVWNTTTPGTDGKTQFSCVTPVAQEVNISTA
                     TGTTSVYHPMSARLVVEKNKSKTDITAGPFSAPATFSITYN"
     gene            complement(85484..86050)
                     /locus_tag="IRB70_000815"
     CDS             complement(85484..86050)
                     /locus_tag="IRB70_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001361645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630764.1"
                     /translation="MRITLHKLAILTGLFLSSSVLATDINVDFTATVKASTCNITLSG
                     DNVTPDGSDTYTLTFPGTIGLDKIANKTTQAQANFNLVASGCTTGVSKINTRLSGNAS
                     GTTPALIVPLSSDTTSTTNYIGMGIKALGEDDSTFLIPNSAPSFIPWEISDTDKTLEL
                     TVALRETTAGSGVPGDFRAQATFNFIYE"
     gene            complement(86070..88670)
                     /locus_tag="IRB70_000816"
     CDS             complement(86070..88670)
                     /locus_tag="IRB70_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000153160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane usher protein"
                     /protein_id="HBC0630765.1"
                     /translation="MSRKIIKTHNNKLTYIASFCALLLSPCAISAEHVEYDNTFLMGQ
                     DASNIDLSRYTEGNPTLPGVYDVSVYINDQPVINQSISFITLEGKKNAQACITLKNLL
                     QFHINKPDINAENSILLQREGELGDCLDLANIIPQASVHYDVNDQRLDINVPQAWIMK
                     NYQNYVDPSLWENGINAAMLAYNVNAYHSEIPDRKNDSVYAAFNGGINLGAWRLRATG
                     NYNWMTNVGSDYDFQNRYLQRDLASLRSQLIVGESYTTGETFDAVSIRGIRLYSDSRM
                     LPPALASFAPIIHGVANTNAKVTITQGGYKIYETTVPPGAFVIDDLSPSGYGSDLIIT
                     IEESDGIKRTFSQPFSSVIQMQRPGVGRWDISAGQVLKDDIQNEPNLFQASYYYGLNN
                     YLTGYTGIQITDNNYTAGLLGLGLNTAYGAFSVDVTHSDVQIPDDKTYRGQSYRISWN
                     KLFEDTRTSLNIAAYRYSTQNYLGLNDALTLIDEVKHPEQDLEPKNMRNYSRMKNQVT
                     VSINQPLKFEKKDYGSFYLAGSWSDYWADGQNNTNYSIGYSNSASWGSYSISAQRSWS
                     QDGGNEDSIYLSFSIPIEKLLGSEHRDSGFQSIDTQLNSDFNGSNQLSISSSGYSTEN
                     HISYSVNTGYSMMKSSDDLGYIGGYASYESPWGTLSSSVSASSDNSRQISFNTDGGFV
                     LHSGGLTFSNDSFSDSDTLAVVQAPGAKGARINYGNSTIDRWGYGVTNALSPYHENRI
                     ALDINGLENDVELKSTSAITVPRQGSVVFAGFETVQGQSAIMNIKRTDGKNIPFAADI
                     YDENGNIIGNVGQGGQAFVRGIEQQGNIRINWLDDGKPVTCLAHYQQSAAPEKIAQTI
                     ILNGISCQIQ"
     gene            complement(88705..89445)
                     /locus_tag="IRB70_000817"
     CDS             complement(88705..89445)
                     /locus_tag="IRB70_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HBC0630766.1"
                     /translation="MFLNAKHTAAVCFATCMSLSASAIADIVISGTRVIYKSNEKSVN
                     VRLENKGNNPLLVQSWLDTGDDSAEPGSITVPFTATPPVSRIDAKRGQTIKLMYTASS
                     PLPKDRESVFWFNVLEVPPKPDADKVANQSLLQLAFRTRIKLFYRPEGLNGLPSDAPA
                     ALKWSWATSAGKTALRVANPTPYHVSFSSGDLVANGKTYPLDVKMVAPLSEETFYIKG
                     MSGKASSAKVHFFAINDFGGAIEGNASL"
     gene            complement(89543..90127)
                     /locus_tag="IRB70_000818"
     CDS             complement(89543..90127)
                     /locus_tag="IRB70_000818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630767.1"
                     /translation="MSKKLGFALSGLMLAMVAGTASAGLDGGQLNISGLVVDNTCETR
                     VDGGNKDGLVLLQTATVAEISAGVLNDTVGAKAKPFSITVDCSNANPNPGSTAKMTFG
                     SVFFGNSKGTLNNDMSINTPSDGVNIALHNIDGSTIKQVQINNPGDIYTKTLDATTKS
                     ATYDFKASYVRAEASQAPTAGYVKTNTAYTITYQ"
BASE COUNT        21504 a        22155 c        24401 g        22175 t
ORIGIN      
        1 tgaatgccgg atgcgctttg cttatccggc ctacaaaatc gcagcgtgta ggccagataa
       61 gacgcgtcag cgtcgcatca ggcgttacat accggatgcg gctacttagc gacgaaaccc
      121 gtaatacact tcgttccagc gcagcgcgtc tttaaacgct ggcaggcgtg tgtcgttatc
      181 aatcaccgtg atttcaatgt cgtgcatctc ggcgaattgg cgcatatcgt tgaggttcag
      241 tgcatggctg aagacggtat ggtgcgcgcc accagcgagg atccacgctt cggaagcagt
      301 tggcagatcc ggttgcgctt tccacagcgc attcgccacc ggcagtttcg gcagggagtg
      361 cggtgttttc accgtgtcga tgcagttaac cagtagacgg taacgatcgc cgagatcaat
      421 caagctggcg acaatcgctg ggccggtttg ggtattgaag atcaggcggg caggatcgtc
      481 cttaccacca ataccgagat gctgaacgtc gaggatcggt ttctcttctg cggcgatcga
      541 cgggcagact tccagcatat gggagccgag caccaggtca ttacctttct cgaagtgata
      601 ggtgtagtcc tccataaagg aggtgccgcc ctgcagaccg gttgacatca ccttcatgat
      661 gcgaagcagg gcggcagttt tccagtcgcc ttcgcccgca aagccgtaac cctgctgcat
      721 cagacgctgt acggccagac caggaagctg tttcagaccg tgcaaatctt caaaggtggt
      781 ggtgaacgcg tggaagccac cttgttccag gaaacgcttc atccccagct caatacgcgc
      841 cgcttccagc acgttctgtc gttttttgcc gtggatttgt gtggcaggcg tcatggtgta
      901 gcagctttcg tactcatcga ccagcgcgtt aacatcgccg tcgctgatgg agttcaccac
      961 ctgcaccaga tcgccaaccg cccaggtatt gacggagaaa ccgaacttga tctgtgcggc
     1021 aactttatcg ccatcggtga ccgccacttc acgcatgtta tcgccaaatc ggcagacttt
     1081 cagatgacgg gtatcctgtt tagagaccgc ctgacgcatc caggagccga tacgctcatg
     1141 ggcttgttta tcctgccagt gaccggtaac cacggcatgt tgctgacgca tacgcgcgcc
     1201 aatgaagccg aactcgcgac cgccatgtgc agtctggttc aggttcataa agtccatatc
     1261 gatactgtcc cacggcagcg ccgcgttgaa ctgggtgtgg aattgcagca acggtttgtt
     1321 gagcatggtc aggccgttga tccacatttt ggccggggag aaggtgtgca gccacaccac
     1381 cagaccagcg caacgatcgt cgtaattcgc gtcgcggcaa atagcggtga tttcatccgg
     1441 cgtggtgccc agcggtttca acaccagttt gcagggcagt ttcgcttccg tattcagcgc
     1501 attaacgacg tgctcggcat gttgggtgac ctgacgcagg gtttccgggc catacagatg
     1561 ctggctgcca atgacaaacc acacttcata attatcaaaa atcgtcatta tcgtgtcctt
     1621 atagagtcgc aacggcctgg gcagcctgtg ccggggcgga agttggaaga tagtgttgtt
     1681 cggcgctcat cgcccattgc tgatagcggc gataaagctg ttcaaagcgt tgtgcctgct
     1741 cgctgcacgg ttgcagggtt ttctctaccg cactggccat tttttgctga gctgatggga
     1801 tgtctgcgtg cactttcgcg gcgacggcag caaaaatcgc cgcaccgagc gcacagcact
     1861 ggtcagaggc aacaatttgc agcgggcgat tcagcacgtc gcagcaggcc tgcataatga
     1921 cctggttttt ccgcgcgatg ccgcccagtg ccatcacgtt attaacggcg atcccctgat
     1981 cggtaaagca ctccatgatt gcgcgtgcgc caaaggcggt ggcagcaatc aaaccgccga
     2041 acagcagcgg agcgtcggta gcgaggttaa gatcggtaat cacccctttc aggcgttggt
     2101 tagcgttcgg tgtgcggcgg ccgttaaacc agtcgagcac caccggcagg tgatccagag
     2161 acggattttt ggcccatgct tcggtcagcg ccggaagcag ttgtttctgg ctggcgttga
     2221 tttgcgtttt cagttccgga tgctgggcgg caagctgttc cagcggccag ccgagtacgc
     2281 gaccaaacca ggcgtagata tcaccaaacg ccgattggcc tgcttccaga ccgataaatc
     2341 caggcaccac gctgccatca acctgaccgc aaataccttt aactgcccgc tcgccaacgc
     2401 tctgtttgtc ggcaatcaga atgtcgcagg tggaagtacc gataactttt accagtgcgt
     2461 taggctgtgc gcctgcgcca actgcgccca tatggcagtc aaacgcgccg ccggaaatca
     2521 ccacgctttc aggcaggccg agacgctgcg cccattccgg gcataaggtg cccaccggaa
     2581 tatcggcagt ccaagtgtca gtgaacagcg gggaaggcaa atggcgattg aggatcgggt
     2641 ccagctcatc aaagaaactg gctggcggca ggccgcccca gctttcgtgc cacagagatt
     2701 tatgcccggc gctgcaacgt ccgcgacgaa tatcctgcgg gcgggtggta ccggaaagca
     2761 gagctggcac ccagtcgcac agctcaatcc acgatgcggc agattgcgcc acggcgctgt
     2821 cctggcgagt cacatgcagg atttttgccc agaaccattc gctggaataa ataccaccaa
     2881 tgtagcggga gtagtcaacg ttgcccggcg cgtggcacaa acgggtaatc tcttccgctt
     2941 cttcaaccgc agtgtggtct ttccacaata cgaacatcgc gttcgggttt tcggcaaact
     3001 ccgggcgcag cgccagcacg tttccgtcgg catcaatcgg tgcgggcgtc gagccggtac
     3061 tgtcaacgcc aatcccgacc acagctgcgc gctgttcgac gctaagctct gcaagcacgg
     3121 ttttcagtgc cgcttccatt gactcaatgt agtcacgcgg atgatgacgg aactggttat
     3181 tcggggcatc acaaaattgc cctttctgcc aacggggata ccactctacg ctggtggcga
     3241 tctcttcacc ggtagcgcag tccaccgcca aagctcgcac agaatcactg ccaaaatcga
     3301 ggccaattgc aatcgccatc gtttcactcc atccaaaaaa acgggtatgg agaaacagta
     3361 gagagttgcg ataaaaagcg tcaggtagga tccgctaatc ttatggataa aaatgctatg
     3421 gcatagcaaa gtgtgacgcc gtgcaaataa tcaatgtgga cttttctgcc gtgattatag
     3481 acacttttgt tacgcgtttt tgtcatggct ttggtcccgc tttgttacag aatgctttta
     3541 ataagcgggg ttaccggttg ggttagcgag aagagccagt aaaagacgca gtgacggcaa
     3601 tgtctgatgc aatatggaca attggtttct tctctgaatg gtgggagtat gaaaagtatg
     3661 gctgaagcgc aaaatgatcc cctgctgccg ggatactcgt ttaacgccca tctggtggcg
     3721 ggtttaacgc cgattgaggc caacggttat ctcgattttt ttatcgaccg accgctggga
     3781 atgaaaggtt atattctcaa tctcaccatt cgcggtcagg gggtggtgaa aaatcaggga
     3841 cgagaatttg tctgccgacc gggtgatatt ttgctgttcc cgccaggaga gattcatcac
     3901 tacggtcgtc atccggaggc tcgcgaatgg tatcaccagt gggtttactt tcgtccgcgc
     3961 gcctactggc atgaatggct taactggccg tcaatatttg ccaatacggg tttctttcgc
     4021 ccggatgaag cgcaccagcc gcatttcagc gacctgtttg ggcaaatcat taacgccggg
     4081 caaggggaag ggcgctattc ggagctgctg gcgataaatc tgcttgagca attgttactg
     4141 cggcgcatgg aagcgattaa cgagtcgctc catccaccga tggataatcg ggtacgcgag
     4201 gcttgtcagt acatcagcga tcacctggca gacagcaatt ttgatatcgc cagcgtcgca
     4261 cagcatgttt gcttgtcgcc gtcgcgtctg tcacatcttt tccgccagca gttagggatt
     4321 agcgtcttaa gctggcgcga ggaccaacgc attagtcagg cgaagctgct tttgagcact
     4381 acccggatgc ctatcgccac cgtcggtcgc aatgttggtt ttgacgatca actctatttc
     4441 tcgcgagtat ttaaaaaatg caccggggcc agcccgagcg agtttcgtgc cggttgtgaa
     4501 gaaaaagtga atgatgtagc cgtcaagttg tcataattgg taacgaatca gacaattgac
     4561 ggcttgacgg agtagcatag ggtttgcaga atccctgctt cgtccatttg acaggcacat
     4621 tatgcaagca ttgctggaac actttattac ccaatccacc gtgtattcat tgatggcggt
     4681 ggtgttggtg gcctttctgg agtcgctggc gctggtcggt ttgattctac ccggtacggt
     4741 gctgatggcg gggctgggag cgctgattgg cagcggcgag ttaagtttct ggcacgcctg
     4801 gctggcaggg attattggct gcttgatggg cgactggatt tctttctggc tgggttggcg
     4861 ttttaaaaag ccgttgcatc gctggtcatt tctgaagaaa aacaaagcac tacttgataa
     4921 aactgaacat gcgttgcatc aacacagcat gttcaccatt ctggtcggtc gttttgttgg
     4981 cccgacgcgt ccgctggtgc caatggtggc gggaatgctg gatctgccgg tggctaaatt
     5041 tattacgccg aatattatcg gctgcctgct gtggccgccg ttttacttcc tgccagggat
     5101 tctggcgggc gcggcgatcg atattcctgc cggaatgcag agcggtgagt ttaaatggtt
     5161 gctgctggca acagcggtgt ttttgtgggt tggtggctgg ctgtgctggc ggttatggcg
     5221 cagcggtaaa gcgactgacc gtttgagtca ttatttgtcc cgcggtcgtt tgttgtggct
     5281 gacgccgttg atttctgcca tcggcgtggt ggcgctggtg gtgttaattc gccacccgtt
     5341 gatgccggtg tatatcgata ttttgcgtaa agtggttggg gtttaggaga tagtcttgtg
     5401 cgggttgcct gatgcgacgc ttgccgcgtc ttatcaggcc tacaaaacgc actacccgta
     5461 ggtcggataa ggcgttcacg ccgcatccga cagtgcatac taacccgtaa tccccaatag
     5521 tgccgaagca ctcgccttac cgctcaacaa ctcattggtc ataccctgcc aggcgatgcg
     5581 cccgtcggcg actactaccg agcgcgtggc gatccgcgcc gcatcttcca cgctgtgcga
     5641 caccatcaat agcgtcattt tttgctgctg gcagctcgtg ctcaccagcg tcaacatctc
     5701 ctgacgtaac gccggatcga gcgcagagaa cggttcatcg agcaataaaa tcggctgttc
     5761 gcgtaccaga caacgcgcta acgccactcg ctgtcgctga ccgccggaaa gctcgcccgg
     5821 taaccgcgcc attaaattat caatccccat ctggcgggcg atagcgtgca ttttcccctg
     5881 ctgtaccgcg ttcagtttca atcccggatt tagccccagc ccgatgttct gtgcgaccgt
     5941 caggtggctg aacaggttgt tctcctgaaa cagcatcgac accggacggc gtgacggcgg
     6001 catagttgtg tgatctacgc catcgatagt cagcgaaccg ctggctggcg tcagaaaacc
     6061 ggcgatcaaa ttcagcaggg tacttttacc cgcgccgctt ggcccgagga tcgccacctg
     6121 ctcgccgcgt tccaccgtta agctaaaacg catcggcaaa tggtggtaaa gccaggtgat
     6181 atcagtcagt tttaacattt cgccccggta gtttttcaat cacggtaaac agcagaaaac
     6241 agagcagcag cagaattaac gcggtgaccg caccgtcctg gctgcgatag gagccaattt
     6301 gctggtagag ataaaacggc agggtgcgga aatcatcgtt accgaacaac gccaccacgc
     6361 caaaatcacc aatcgacagc acgcatgcaa aggccagcgc ctgcgccagt ggacgtttca
     6421 gggcgcgcag ctccaccact tttaagcgtg accagccttc aatccccagc gactgacata
     6481 acatgctgta gcgggcggtg atatcgcgca tcgggttttc cagcactttc agcgcataag
     6541 ggatcgccat taacgcattg gtgaaaatca caatgccgtc agcagattgt ggcaggccga
     6601 tagtgttgtt gagcagtaaa aagaagccgg tagccagcac aatccccggc atggcgagga
     6661 tcaacatgcc gctcatctcc agcacctgac ccgccagcat tttctgccgc gcccgcagtt
     6721 cgcgactgct ccatagcagc atcatggtca gcactacgca caatacacct gccgccagcg
     6781 caatacgcaa cgaggtccac agcgcctgcc acagcaccgg ttgtgccagc acttccggca
     6841 actggcgatt taccccatcg acgatcaccg ccagtaacgg tggcagcaac agcagcagcg
     6901 ccagcacaat taacaccgtg tcgcaaatgc ggctatgcag acgatcgtcc gggtcgcgcc
     6961 agccttgcag cagcgtggtg ccgggcgcaa tggccttact caatcgctga ctcaacagca
     7021 ccagcccgag gcagcacacc atctggagca gcgccagcat tgccgcgcgg gcaggatcgt
     7081 agtcgtaact cagcgcctga tagattgcca gctcgatagt ggtcgcctgc ggaccgcccc
     7141 ccagcgatag cacggtggcg aagctggcga aacagagcat aaagataagc gcagcaaccg
     7201 gcgggatttg tcgccgtaac cacggccatt cgacgaagcg gaaaaaatgc cagctacgca
     7261 tcccaagctg ggcggcaagt tgacgctgtt cgccggggat gttttccagt gcctggagta
     7321 ataagcggct cgccatcggc agattaaaaa acacatgggc cagcaaaata ccttgcaggc
     7381 cgtagggcga aaaggtccac tccagaccga gcgattggca gagtgttgcc agccagccct
     7441 ggcgaccata gacgctaaga atgccgaaaa cagcgaccaa caccgggagg atcaaggtca
     7501 ttgcacacag acgcaacagc gccagccgac ccggaaagcg cctgcgatag agcgcgcggg
     7561 cgaggaatat cgcgggtatg acagagagca gtgccgagag aaacgcctgc cagaaggaga
     7621 agcgcaccac atgccacaga tagctgtcct gccagactgc cacccagtca tcctgcggcg
     7681 cgttccacca cagggcgaga aacgccgcca gcgcaaccgc taccaccagc gtggtggcgc
     7741 ttacacctgg aattaaccag ccgggaatta acggctgacg gcgcgttgcc attcgctaat
     7801 ccatgcctga cgttgtgccg ccacttcggc tggcgtgaac tccaacgtgg ttgcgggttt
     7861 ggtcaatttt tcaaaaccgg caggcagcgt gacgtttgcc accggataca tccagttgcc
     7921 ggttgggatc gcattctgga aagccggaga aaccataaac tggaggaatt tttgcgccag
     7981 ctccggctgc ttgctggcag cggtgcgggc ggcgacttcc acttgcagat agtgaccttc
     8041 gctgaagttc gcggcggcgt agttatcttt cttctcttcg agaatgtgat aagccggaga
     8101 ggtggtgtaa ctcagtacca gatcgctttc accttttaaa aacaggccgt aggcttcgct
     8161 ccagcctttg gtgaccgtga ccgttttctt cgccagtttc tgccaggctt gtggggcgtc
     8221 atcgccatag actttttgca tccatagcaa cagacccagc cccggtgtac tggtgcgcgg
     8281 atcctgataa atcacccgcc agttttgatc gctctcaacc agttctttca ggctttgtgg
     8341 cgggtttttc agtttgttct tgtcataaac gaaggcgaag tagccataat caaacggtac
     8401 gaaagtgtca ttattccagc cgccgggaac gttaacggca tccgctgcca caccgctttt
     8461 ggcaaacagt ccggttttac tggcggcgtc taacaggttg ttatccagcc ccagcaccac
     8521 atcggcttta ctgtttttgc cttccatccg tagacggttg agaagcgaaa cgccatcttc
     8581 cagcgccacc agtttcagtt cgcaattaca gtcggcttca aaggcttttt taaccaccgg
     8641 accaggcccc cagtcggcgg cgaaggaatc gtaggtataa acagtcagaa cgggtttagc
     8701 gaaaacgggc gctgtgcaca gcaacagcag gggcagacat ttttttaaca ctttgcacct
     8761 caaaaaagag tggcaaagga cttgagaagg agcctcaaat cccttcgccg gcgttatccg
     8821 gatcaggttc gacgggtatt ttctcagcgc acgcgtacgc gtggcacccc gttgagaacg
     8881 gcgttagtgt agtgattttg ttatcaacca gcaatcatgg atccggtggc gcaaaccacg
     8941 ctgatttaaa atcgaaccag ccgagggtat tcatgcgcag gccgcgcata ctgcgttgcc
     9001 cctgaatgat cagccagtgg tgcaataatg gcaccatcgc tttgctggcg accagttgct
     9061 ggcaccagtt cgccagattc atctcgccat tgcgccagcg agcagcgtcg gcttgccagt
     9121 caatgggaat gcaatgttgt agcagtggca cttcgcataa atgtgcgaaa acagagaagt
     9181 ccagcggcag ggtaaagttg gcgctgttta gccagatatc actttcgatc tctcctgtat
     9241 gccactgatc gtagtcgatc tctttgattt tcagcgtgac ctggtgactt gccagaatct
     9301 gctgcatgat cccggcaatc acccgatgct cactgtgatc ctgataaaag gttagggtga
     9361 ggctttccag gccagccggt ttttcgctct ttatggtgcg ggcatggtgc caacggggga
     9421 gcagtccata agccgggaac cacagttgct ggtactgttc ctcagcgaaa tagaccagat
     9481 tagttggaga aagcacatag cttacccagt ccctgacttg ctgattcgcc ccgcgatggg
     9541 tgcggctgtc gaacagtaaa tagtagcaac cttcctccag gcggctttca atctcttttt
     9601 cctcgccctg tggacctttt agcatcagcc ctccggctgg ctcgtcggca atttccggca
     9661 gaacccagac gttaacttcg tcgattaatg cccggtaacc gaagaagtca tcgaatgcct
     9721 gaattttcag ttgattggtg ctgttgcgaa tcaccgcata cggaccggtg ccgatgggat
     9781 ggctggcaaa gttactgagg gtttcccatt cgcgcggcag gatcatcgcc ggaacttgcc
     9841 ccagcagtaa cggtaaccag cggtccggtt gcgtgagatg gatatccagc gtccagggcg
     9901 tcggcgacac aatgtcagca atatgcgaat agagcggcag cgtattgatt cgttttaaag
     9961 aggcgatcac atcgtccatt tccagttcac gaccatggtg aaaatggact cctggacgca
    10021 aaaagaaacg ccagtgaagc ggtgaaattt gctgccagtg gtgggcgatg tctgcttcca
    10081 gttccccatt ttcctcattt atgcgcgtta gcgaactgaa gatttgccgg gcgatatggg
    10141 tttcggaacg gcgcaatgcg ctgccaggta gcagattacg caacggacga tagtagagca
    10201 cgcgcaggat gtgccgcccc tggcggaagc tgcggcccag atgagaaacc agcatttgcc
    10261 gcacagtcgc tttgtcgcca accaactgca ccagttgatc gatacgatcc tgctccagca
    10321 ggtcttccgc ccgctgttgc tgaagcgcca gcccggtata gaggaatgtc agacgcgagc
    10381 gtttaccgcg cccgacttcc gcttcccacg tcagccagcc gcgatcctgc atggtgttga
    10441 gcagggtgcg catatgacga cgcgagcagc tcaataacgc tgccagttcg ttgagcgttg
    10501 tgtcctgcga tttaccctcg cagcattgcc acaggcggat gaactgttgt tgcagacgag
    10561 cagatggcat aaaaggggaa ctcctgtgca aaagacagca attttatttt ccctatatta
    10621 agtcaataat tcctaacgat gaagcaaggg ggtgccccat gcgtcagttt tatcagcact
    10681 attttaccgc gacagcgaag ttgtgctggt tgcgttggtt aagcgtccca caacgattaa
    10741 ccatgcttga aggactgatg cagtgggatg accgcaattc tgaaagttga cttgcctgca
    10801 tcatgtgtga ctgagtattg gtgtaaaatc acccgccagc agattatacc tgctggtttt
    10861 ttttattctc gccgcgctaa aaagggaacg tatgatctgg ataatgacga tggctcgccg
    10921 tatgaacggt gtttacgcgg catttatgct ggtcgctttt atgatggggg gggccggggc
    10981 gctacaggct cctacattga gcttatttct gagtcgtgag gttggcgcgc aacctttctg
    11041 gatcggcctc ttttatacgg tgaatgctat tgctgggatc ggcgtaagcc tctggttggc
    11101 aaaacgttct gacagtcagg gcgatcggcg aaaactgatt atattttgct gtttgatggc
    11161 tatcggcaat gcgctattgt ttgcatttaa tcgtcattat ctgacgctta tcacctgtgg
    11221 tgtgcttctg gcatctctgg ccaatacggc aatgccacag ttatttgctc tggcgcggga
    11281 atatgcggat aactcggcgc gagaagtggt gatgtttagc tcggtgatgc gtgcgcagct
    11341 ttctctggca tgggttatcg gtccaccgtt ggcctttatg ctggcgttga attacggctt
    11401 tacggtgatg ttttcgattg ccgccgggat attcacactc agtctggtat tgattgcatt
    11461 tatgcttccg tctgtggcgc gggtagaact gccgtcggaa aatgctttat caatgcaagg
    11521 tggctggcag gatagtaacg tacggatgtt atttgtcgcc tcgacgttaa tgtggacctg
    11581 caacaccatg tacattattg atatgccgtt gtggatcagt agcgagttag gattgccaga
    11641 caaactggcg ggtttcctga tggggacggc agctggactg gaaataccag caatgattct
    11701 ggctggctac tatgtcaaac gttatggtaa gcggcgaatg atggtcatag cagtggcggc
    11761 aggagtactg ttttacaccg gattgatttt ctttaatagc cgtatggcgt tgatgacgct
    11821 gcaacttttt aacgctgtat ttatcggcat tgttgcgggt attgggatgc tatggtttca
    11881 ggatttaatg cctggaagag cgggggcagc taccacctta tttactaaca gtatttctac
    11941 cggggtaatt ctggctggcg ttattcaggg agcaattgca caaagttggg ggcactttgc
    12001 tgtctactgg gtaattgcgg ttatttctgt tgtcgcatta tttttaaccg caaaggttaa
    12061 agacgtttga tgacgtggac gatagcggaa agcccggtca tttgaccggg caaggggatt
    12121 aattcataaa cgcaggttgt tttgcttcat aagcggcaat ggcgtcgtcg tgctgcaagg
    12181 taagcccaat actgtccaga ccgttcatca tgcagtggcg gcggaaggca tcgatggtaa
    12241 agcgataggt tttctctccc gctttcacct cttgcgcttc cagatccacg tcgaaatgga
    12301 tccccggatt agctttcacc agcgcaaaca gttcgtccac ttctgcatcg cttaatttca
    12361 ccggcagcag ctggttgtta aagctattgc cgtagaagat gtcagcaaaa ctcggcgcaa
    12421 tcaccacttt aaaaccgtag tcggtcaatg cccagggcgc gtgctcacgc gaagagccac
    12481 agccgaagtt ttctcgtgcc agcaaaatgg aagcgccctg atactgcggg aagttcagca
    12541 cgaagtccgg gtttggctgt tggccttttt catccagaaa acgccagtcg ttaaacagat
    12601 gcgcgccaaa acccgtacgg gtcactttct gcaaaaactg tttcgggatg attgcatcgg
    12661 tatcgacatt ggcggcatcc agcggaacca ccaggcctgt gtgtttgata aatttctctg
    12721 ccatggtgtg ctccttattt aatgttgcga atgtcggcga aatgtccggt cacagcagca
    12781 gcggcagcca ttgccgggct gaccagatgc gtgcgcccgc cgcgcccctg gcggccttca
    12841 aagttacggt tgctggtgga ggcacaacgt tcgcccggat tcagacggtc gttgttcatc
    12901 gccagacaca ttgagcagcc aggcaagcgc cattcaaaac cggcttcaat aaagatttta
    12961 tccagacctt ccgcttccgc ctgggctttt accgggccag agccgggaac caccagtgcc
    13021 tgcacgcctg gcgcgacttt tcgccctttg gcgatctccg ctgccgcgcg taaatcttca
    13081 atgcgcgagt tggtacagga accgataaac actttgtcga tagccacttc ggtcagcgga
    13141 atacccggtt tcagccccat ataggccagc gctttttctg ccgacgcgcg ttcaaccgga
    13201 tcggcaaacg aagccggatc gggaatattg tcgttcacgg aaatcacctg gccgggattg
    13261 gtgccccagg tgacctgcgg tgaaatttct tctgcttgca gagtgacaac ggtatcgaaa
    13321 gttgcgcctt cgtcggtttg cagggttttc cagtaggcaa cggcgtcgtc gaaatctttg
    13381 cctttcggcg catgcagacg gcctttgaca tagttaaagg tggtttcgtc cggtgcaacc
    13441 agaccggctt ttgcgcccat ttcgattgcc atattgcaca gggtcatacg accttccatg
    13501 cttaaatcac ggattgcttc gccgcaaaac tccaccacat gcccggtgcc gcctgcgcta
    13561 ccggttttac cgataattgc cagcacgata tcttttgcgg taatacccgg cgcggctttg
    13621 ccctggactt caattttcat ggtttttgcg cggccctgtt tcagggtttg cgttgccagt
    13681 acgtgttcaa cttcggaagt gccgatacca aaggccagtg cgccaaacgc gccgtgggtg
    13741 gcggtatgcg agtcgccgca gacaatggtc atccccggca aggtgacgcc ctgttccggc
    13801 cccattacgt ggacgatccc ctgatacggg tgattcaggt catacagttc gacgccaaat
    13861 tctttgcagt ttttgatcag ttcctgcatc tggatacgcg ccatttcacc gcaggcatta
    13921 atgtctttgg tctgggtaga gacgttgtga tccatggtag cgaaggtttt gcccggctga
    13981 cgtaccgggc gaccgtgggc gcgcagacca tcgaacgcct gcggtgaggt cacttcatgc
    14041 accaggtggc ggtcgatata taacagtggg gtttcgtttt cggcttcgta cacaacgtga
    14101 gcgtcgaaca atttttcgta taacgtctta gccatgatta caccccttct gctacatagc
    14161 gggcaatgat atcgcccatt tcatcggtac taacggcggc agcgccacgg gctaaatccc
    14221 cggtgcgaat gccttcttct aatgcgcggt taatggcgcg ttcaatggcg caagccgcat
    14281 catcggcatc caggctgtaa cgcagcagca gtgccagcga aaggatttgt gcaatcgggt
    14341 tggcgatgtt tttgcctgcg atatctggtg ccgagccgcc cgccggttca tacagtccaa
    14401 aaccttgctc gttcaggctg gcggaaggca acatccccat cgagccagtg atcattgcgc
    14461 actcgtcaga cagaatgtcg ccaaacaggt tggagcacag cagaacgtca aactgtgatg
    14521 gatctttaat cagctgcatg gtggcgttgt cgatgtacat atgcgccagt tcgacatccg
    14581 ggtattccgt ggcgatctcg ttaacgatct cccgccataa aatagaggat tgcagcacgt
    14641 tggctttatc gatcgacgtc actttgtggc gacgcttgcg agcagattca aacgcgatgc
    14701 gggcgatacg ttcgatctca aaacggtgat acacctcggt atcaaaggct ttttcatatt
    14761 gtccgctacc ttcgcggcct tttggctgac cgaaatagat gccgccggtc agttcgcgca
    14821 cacacaggat gtcgaagccg tttgcggcaa tgtctgcacg cagcggacag aatgcttcca
    14881 gcccctgata cagttttgcc gggcgcaggt tgctgaataa tttgaagtgc ttacgcagag
    14941 gcagcagcgc gccgcgttct ggttgctggt ctggtggtaa atgttcccac ttcgggccgc
    15001 ctaccgagcc aaacagcacg gcatcggctt gctcacaacc ttcaaccgtc gcaggcggca
    15061 gtggttgccc gtggttatca atggctgcgc cgcctacatc gtaatggctg gtggtgatgc
    15121 gcatcgcaaa gcggttgcgc acggcatcca gcactttcag cgcctgggtc atcacttccg
    15181 gaccaatacc gtcccccggc aatacggcaa tatggtaatt cttcgacatc acacggtttc
    15241 cttgttgttt tcgttgtgtt gagctttgcg ttgcaactct ttttcgactt ctgcggcacg
    15301 ccagatattg ttcagaacgt gcaccatggc tttggcagat gactcgacaa tatcggtagc
    15361 caggccgacg ccgtggaagc ggcgaccgtt gtagttagcg acgatatcca cctgacccag
    15421 cgcatcttta ccgtggcctt tggcggtcag gctgtatttc accagttcga cgttatattc
    15481 agtgatgcgg ttaattgcct gatagacggc atcgaccgga ccgttaccgt tggcggcttc
    15541 tgctttgact tcttcgccac aggccagttt gacggcggcg gtggcgatat cgttagagcc
    15601 agactgcacg ctgaagtaat ccagacggaa atgctccggc tcttcttgct gcttaccgat
    15661 gaaggccagc gcctccagat cgtaatcaaa cacctgacct tttttgtccg ccagcttcag
    15721 gaaagcatcg tacaaattgt ctaaattata ttcactttct ttatacccca tctcatccat
    15781 gcgatgtttc accgccgcac gccccgaacg agaggtcaga ttcagctgga tttggttcag
    15841 accaatagat tctggtgtca tgatttcgta gttttcgcgg tttttcagca cgccatcctg
    15901 gtgtataccg gaggagtgtg cgaatgcgcc gctgccaaca atggctttgt ttgccgggat
    15961 cggcatatta caaatctggc taactaactg gctggtgcgc catatctcct ggtgattaat
    16021 ggcggtgtgg acgttgagaa tatccttacg aactttgatc gccatgatga cttcttccag
    16081 ggaacagttt ccggcacgct cgccgatccc gttcattgcg ccttccacct ggcgtgcacc
    16141 ggcatgtacc gccgccagtg agtttccgac cgccaggccc aaatcgtcgt gggtatgtac
    16201 ggagataatg gctttgtcga tgttaggcac gcgttcatac aggccgctga tgattccggc
    16261 gaactcaaac ggcatggtgt agcccacggt gtccggaatg ttgatggtgg tggcaccggc
    16321 attaatcgcc gcttcgacca ctcgcgccag atcggcaatg ggtgtacgcc cggcatcttc
    16381 gcaagaaaat tcaacatcat cggtgtaatt acgggcgcgt ttcaccatat agatagcgcg
    16441 ttcgatcacc tcgtccagcg tgctgcgcag cttggtggcg atgtgcattg gcgaagtggc
    16501 aataaaggta tgaatacgga aggcttcggc gactttcagg gattcggccg ccacgtcgat
    16561 atctttttcc acgcagcgag ctaacgcaca tacgcggctg tttttaacct ggcgggcgat
    16621 ggtttgcacc gattcaaaat cgcccggcga agagacgggg aaaccgactt ccatcacgtc
    16681 aacacccata cgctcaaggg ccagcgcaat ttgcagtttt tctttcacac tcaagcttgc
    16741 ctgtaacgcc tgttcaccgt cgcgcaatgt ggtatcgaaa ataatgactt gctggctcat
    16801 ggtttgggtc cttgtctctt ttagagcgcc tcgcttcggg cataaaaaaa cccgcgcaat
    16861 ggcgcgggtt ttttgtttga ctgcgtgctg gcttaatgct ggatgccgct cactcgtcta
    16921 ccgcgcaaag aagatgcgtt tagtagtagt agaccgataa agcgaacgat gtgagtcatt
    16981 aaatcagctc cagatgaatg cgatatgctt ttagagttac tggatacaaa aacggatgtc
    17041 aaccctgacg caataaaaac gtcccgccag cgtgagttct gcatccgtaa aattagctaa
    17101 ttgtgctgcg gtggttaaag taagcgatat taatttctgc ttaactaccg acgcttttca
    17161 tcggttgaca tatttcagca taaatttttg catctaatca acgaggaaaa aggggacaaa
    17221 atgcacgcgt tgcaaaacct atcctgatga tttgtattga attatatgtt ttgcgatttt
    17281 ttttgatatt gatttggtga atattattga tcaattaatg ttaagaatta atgcattaaa
    17341 tatataaatt aattattaaa taagcacatt taatccattt tgtagatgat tgagtattcg
    17401 cggtagttat gattagattg ttttcgcaac aaaaacatta tggattatta tgctgtggta
    17461 aatgactcat tccacggcaa tggattctgt ttttatcaga acccgtatct ttatgttttc
    17521 cgaattttac tcattttgct ttttcttatt ttatatgcat gataaatcat attcttcagg
    17581 attatttctc tgcattccaa taagggaaag ggagttaagt gtgacagtgg agttaagtat
    17641 gccagaggta caaacagatc atccagagac ggcggagtta agcaaaccac agctacgcat
    17701 ggtcgatctc aacttattaa ccgttttcga tgccgtgatg caggagcaaa acattactcg
    17761 tgccgctcat gttctgggaa tgtcgcaacc tgcggtcagt aacgctgttg cacgcctgaa
    17821 ggtgatgttt aatgacgagc tttttgttcg ttatggccgt ggtattcaac cgactgctcg
    17881 cgcatttcaa ctttttggtt cagttcgtca ggcattgcaa ctagtacaaa atgaattgcc
    17941 tggttcaggt tttgaacccg cgagcagtga acgtgtattt catctttgtg tttgcagccc
    18001 gttagacagc attctgacct cgcagattta taatcacatt gagcagattg cgccaaatat
    18061 acatgttatg ttcaagtctt cattaaatca gaacactgaa catcagctgc gttatcagga
    18121 aacggagttt gtgattagtt atgaagactt ccatcgtcct gaatttacca gcgtaccatt
    18181 atttaaagat gaaatggtgc tggtagccag caaaaatcat ccaacaatta agggcccgtt
    18241 actgaaacat gatgtttata acgaacaaca tgcggcggtt tcgctcgatc gtttcgcgtc
    18301 atttagtcaa ccttggtatg acacggtaga taagcaagcc agtatcgcgt atcagggcat
    18361 ggcaatgatg agcgtactta gcgtggtgtc gcaaacgcat ttggtcgcta ttgcgccgcg
    18421 ttggctggct gaagagttcg ctgaatcctt agaattacag gtattaccgc tgccgttaaa
    18481 acaaaacagc agaacctgtt atctctcctg gcatgaagct gccgggcgcg ataaaggcca
    18541 tcagtggatg gaagagcaat tagtctcaat ttgcaaacgc taactgattg cagaataggt
    18601 cagacatgaa tgtctggttt attctgcatt ttttattgaa tgtagaattt tattctgaat
    18661 gtgtgggctc tctattttag gattaattaa aaaaatagag aaattgctgt aagttgtggg
    18721 attcagccga tttattatca atttaatcct ctgtaatgga ggattttatc gtttcttttc
    18781 acctttcctc ctgtttattc ttattacccc gtgtttatgt ctctggctgc caattgctta
    18841 agcaagatcg gacggttaat gtgttttaca cattttttcc gtcaaacagt gaggcaggcc
    18901 atggagatgt tgtctggagc cgagatggtc gtccgatcgc ttatcgatca gggcgttaaa
    18961 caagtattcg gttatcccgg aggcgcagtc cttgatattt atgatgcatt gcataccgtg
    19021 ggtggtattg atcatgtatt agttcgtcat gagcaggcgg cggtgcatat ggccgatggc
    19081 ctggcgcgcg cgaccgggga agtcggcgtc gtgctggtaa cgtcgggtcc aggggcgacc
    19141 aatgcgatta ctggcatcgc caccgcttat atggattcca ttccattagt tgtcctttcc
    19201 gggcaggtag cgacctcgtt gataggttac gatgcctttc aggagtgcga catggtgggg
    19261 atttcgcgac cggtggttaa acacagtttt ctggttaagc aaacggaaga cattccgcag
    19321 gtgctgaaaa aggctttctg gctggcggca agtggtcgcc caggaccagt agtcgttgat
    19381 ttaccgaaag atattcttaa tccggcgaac aaattaccct atgtctggcc ggagtcggtc
    19441 agtatgcgtt cttacaatcc cactactacc ggacataaag ggcaaattaa gcgtgctctg
    19501 caaacgctgg tagcggcaaa aaaaccggtt gtctacgtag gcggtggggc aatcacggcg
    19561 ggctgccatc agcagttgaa agaaacggtg gaggcgttga atctgcccgt tgtttgctca
    19621 ttgatggggc tgggggcgtt tccggcaacg catcgtcagg cactgggcat gctgggaatg
    19681 cacggtacct acgaagccaa tatgacgatg cataacgcgg atgtgatttt cgccgtcggg
    19741 gtacgatttg atgaccgaac gacgaacaat ctggcaaagt actgcccaaa tgccactgtt
    19801 ctgcatatcg atattgatcc tacttccatt tctaaaaccg tgactgcgga tatcccgatt
    19861 gtgggggatg ctcgccaggt cctcgaacaa atgcttgaac tcttgtcgca agaatccgcc
    19921 catcaaccac tggatgagat ccgcgactgg tggcagcaaa ttgaacagtg gcgcgctcgt
    19981 cagtgcctga aatatgacac tcacagtgaa aagattaaac cgcaggcggt gatcgagact
    20041 ctttggcggt tgacgaaggg agacgcttac gtgacgtccg atgtcgggca gcaccagatg
    20101 tttgctgcac tttattatcc attcgacaaa ccgcgtcgct ggatcaattc cggtggcctc
    20161 ggcacgatgg gttttggttt acctgcggca ctgggcgtca aaatggcgtt gccagaagaa
    20221 accgtggttt gcgtcactgg cgacggcagt attcagatga acatccagga actgtctacc
    20281 gcgttgcaat acgagttgcc cgtactggtg gtgaatctca ataaccgcta tctggggatg
    20341 gtgaagcagt ggcaggacat gatctattcc ggccgtcatt cacaatctta tatgcaatcg
    20401 ctacccgatt tcgtccgtct ggcggaagcc tatgggcatg tcgggatcca gatttctcat
    20461 ccgcatgagc tggaaagcaa acttagcgag gcgctggaac aggtgcgcaa taatcgcctg
    20521 gtgtttgttg atgttaccgt cgatggcagc gagcacgtct acccgatgca gattcgcggg
    20581 ggcggaatgg atgaaatgtg gttaagcaaa acggagagaa cctgattatg cgccggatat
    20641 tatcagtctt actcgaaaat gaatcaggcg cgttatcccg cgtgattggc cttttttccc
    20701 agcgtggcta caacattgaa agcctgaccg ttgcgccaac cgacgatccg acattatcgc
    20761 gtatgaccat ccagaccgtg ggcgatgaaa aagtacttga gcagatcgaa aagcaattac
    20821 acaaactggt cgatgtcttg cgcgtgagtg agttggggca gggcgcgcat gttgagcggg
    20881 aaatcatgct ggtgaaaatt caggccagcg gttacgggcg tgacgaagtg aaacgtaata
    20941 cggaaatatt ccgtgggcaa attatcgatg tcacaccctc gctttatacc gttcaattag
    21001 caggcaccag cggtaagctt gatgcatttt tagcatcgat tcgcgatgtg gcgaaaattg
    21061 tggaggttgc tcgctctggt gtggtcggac tttcgcgcgg cgataaaata atgcgttgag
    21121 aatgatctca atgcgcaatt tacagcccaa catgtcacgt tgggcttttt ttgcgaaatc
    21181 agtgggaacc tggaataaaa gcagttgccg cagttaattt tctgcgctta gatgttaatg
    21241 aatttaaccc ataccagtac aatggctatg gtttttacat tttacgcaag gggcaattgt
    21301 gaaactggat gaaatcgctc ggctggcggg agtgtcgcgg accactgcaa gctatgttat
    21361 taacggcaaa gcgaagcaat accgtgtgag cgacaaaacc gttgaaaaag tcatggctgt
    21421 ggtgcgtgag cacaattacc acccgaacgc cgtggcagct gggcttcgtg ctggacgcac
    21481 acgttctatt ggtcttgtga tccccgatct ggagaacacc agctataccc gcatcgctaa
    21541 ctatcttgaa cgccaggcgc ggcaacgggg ttatcaactg ctgattgcct gctcagaaga
    21601 tcagccagac aacgaaatgc ggtgcattga gcacctttta cagcgtcagg ttgatgccat
    21661 tattgtttcg acgtcgttgc ctcctgagca tcctttttat caacgctggg ctaacgaccc
    21721 gttcccgatt gtcgcgctgg accgcgccct cgatcgtgaa cacttcacca gcgtggttgg
    21781 tgccgatcag gatgatgccg aaatgctggc ggaagagtta cgtaagtttc ccgccgagac
    21841 ggtgctttat cttggtgcgc taccggagct ttctgtcagc ttcctgcgtg aacaaggttt
    21901 ccgtactgcc tggaaagatg atccgcgcga agtgcatttc ctgtatgcca acagctatga
    21961 gcgggaggcg gctgcccagt tattcgaaaa atggctggaa acgcatccga tgccgcaggc
    22021 gctgttcaca acgtcgtttg cgttgttgca aggagtgatg gatgtcacgc tgcgtcgcga
    22081 cggcaaactg ccttctgacc tggcaattgc cacctttggc gataacgaac tgctcgactt
    22141 cttacagtgt ccggtgctgg cagtggctca acgtcaccgc gatgtcgcag agcgtgtgct
    22201 ggagattgtc ctggcaagcc tggacgaacc gcgtaagcca aaacctggtt taacgcgcat
    22261 taaacgtaat ctctatcgcc gcggcgtgct cagccgtagc taagccgcga acaaaaatac
    22321 gcgccaggtg aatttccctc tggcgcgtag agtacgggac tggacatcaa tatgcttaaa
    22381 gtaaataaga ctattcctga ctattattga taaatgcttt taaacccgcc cgttaattaa
    22441 ctcaccagct gaaattcaca ataattaagt gatatcgaca gcgcgttttt gcattatttt
    22501 gttacatgcg gcgatgaatt gccgatttaa caaacacttt tctttgcttt tgcgcaaacc
    22561 cgctggcatc aagcgccaca cagacgtaac aaggactgtt aaccggggaa gatatgtcct
    22621 aaaatgccgc tcgcgtcgca aactgacact ttatatttgc tgtggaaaat agtgagtcat
    22681 tttaaaacgg tgatgacgat gagggatttt ttcttacagc tattcataac gttaatttgc
    22741 ttcgcacgtt ggacgtaaaa taaacaacgc tgatattagc cgtaaacatc gggtttttta
    22801 cctcggtatg ccttgtgact ggcttgacaa gcttttcctc agctccgtaa actcctttca
    22861 gtgggaaatt gtggggcaaa gtgggaataa ggggtgaggc tggcatgttc cggggagcaa
    22921 cgttagtcaa tctcgacagc aaagggcgct tatcagtgcc tacccgttat cgggaacagc
    22981 tgcttgagaa cgctgccggt caaatggttt gcaccattga catttatcac ccgtgcctgc
    23041 tgctttaccc cctgcctgaa tgggaaatta tcgagcaaaa attatcgcgt ctgtcgagca
    23101 tgaacccggt tgagcgccgt gtgcagcgcc tactgttagg tcatgccagc gaatgtcaga
    23161 tggatggcgc aggtcgattg ttaatcgcgc cagtactgcg gcaacatgcc gggctgacaa
    23221 aagaagtgat gctggttgga cagttcaaca agtttgagct gtgggatgaa acaacctggc
    23281 atcaacaggt caaggaagat atcgacgcag agcagttggc taccggagac ttatcggagc
    23341 gactgcagga cttgtctcta taaaatgatg gaaaactata aacatactac ggtgctgctg
    23401 gatgaagccg ttaatggcct caatatccgt cctgatggca tctacattga tgggactttt
    23461 ggtcgcggtg gtcactcacg tctgatcctc tcgcagcttg gcgaagaggg gcgtttgctg
    23521 gcgatcgatc gcgacccgca ggctatcgcc gttgcgaaga ctattgatga tccgcgcttc
    23581 tccatcatcc acggaccttt ctccgcgctg ggcgaatacg ttgccgagcg cgatcttatc
    23641 ggcaagatcg acggcattct cctcgatctt ggcgtctctt caccgcaact tgatgatgct
    23701 gaacgtggct tttcctttat gcgcgatggt ccgctggaca tgcgtatgga cccaacccgt
    23761 gggcagtcag ccgctgaatg gctacaaacc gcagaagaag ccgatatcgc ctgggtattg
    23821 aaaacctatg gtgaagagcg ttttgccaaa cgcattgccc gcgccattgt cgagcgtaac
    23881 cgcgaacagc cgatgacccg caccaaagaa ctggcggaag tcgtggctgc tgcaacgccg
    23941 gtgaaagata agtttaaaca tcccgcgacc cgtaccttcc aggcggtgcg catttgggta
    24001 aacagtgaac tggaggagat agagcaggcg ctaaaaagct cgctcaacgt gctggccccg
    24061 ggtgggcggc tttcgatcat cagcttccac tcgctggaag accgtattgt gaaacgtttt
    24121 atgcgtgaaa acagccgcgg tccgcaagtt ccggcagggt taccgatgac tgaagagcag
    24181 ctcaaaaaac tgggtggccg tcagctgcga gcactaggca agttaatgcc gggcgaagaa
    24241 gaggtggctg agaaccctcg tgcccgtagt tcagttctgc gtattgcaga gaggacgaat
    24301 gcatgatcag cagagtgaca gaagctctaa gcaaagttaa aggatcgatg ggaagccacg
    24361 agcgccatgc attgcctggt gttatcggtg acgatctttt gcgatttggg aagctgccac
    24421 tctgcctgtt catttgcatt attttgacgg cggtgactgt ggtaaccacg gcgcaccata
    24481 cccgtttact gaccgctcag cgcgaacaac tggtgctgga gcgagatgct ttagacattg
    24541 aatggcgcaa cctgatcctt gaagagaatg cgctcggcga ccatagccgg gtggaaagga
    24601 tcgccacgga aaagctgcaa atgcagcatg ttgatccgtc acaagaaaat atcgtagtgc
    24661 aaaaataagg ataaacgcga cgcatgaaag cagcggcgaa aacgcagaaa ccaaaacgtc
    24721 aggaagaaca tgccaacttt atcagttggc gttttgcgtt gttatgcggc tgtattctcc
    24781 tggcgctggc ttttctgctc ggacgcgtag cgtggttaca agttatctcc ccggatatgc
    24841 tggtgaaaga gggcgacatg cgttctcttc gcgttcagca agtttccacc tcccgcggca
    24901 tgattactga ccgttctggt cgcccgttag cggtgagcgt gccggtaaaa gcgatttggg
    24961 ctgacccgaa agaagtgcat gacgctggcg gtatcagcgt cggtgaccgc tggaaggcac
    25021 tggctaacgc gctcaatatt ccgctggatc agctttcagc ccgcattaac gccaacccga
    25081 aagggcgctt tatttatctg gcgcgtcagg tgaaccctga catggcggac tacatcaaaa
    25141 aactgaaact gccggggatt catctgcgtg aagagtctcg ccgttactat ccgtccggcg
    25201 aagtgactgc tcacctcatc ggctttacta acgtcgatag tcaagggatt gagggcgttg
    25261 agaagagttt cgataaatgg cttaccgggc agccgggtga gcgcattgtg cgtaaagacc
    25321 gctatggtcg cgtaattgaa gatatttctt ctactgacag ccacgcagcg cacaacctgg
    25381 cgctgagtat tgatgaacgc ctgcaggcgc tggtttatcg cgaactgaac aacgcggtgg
    25441 cctttaacaa ggctgaatct ggtagcgccg tgctggtgga tgtcaacacc ggtgaagtgc
    25501 tggcgatggc taacagcccg tcatacaacc ctaacaatct gagcggcacg ccgaaagagg
    25561 cgatgcgtaa ccgtaccatc accgacgtgt ttgaaccggg ctcaacggtt aaaccgatgg
    25621 tggtaatgac cgcgttgcaa cgtggcgtgg tgcgggaaaa ctcggtactc aataccattc
    25681 cttatcgaat taactatcga attaacggcc acgaaatcaa agacgtggca cgctacagca
    25741 aattaaccct gaccggggta ttacagaagt cgagtaacgt cggtgtttcc aagctggcgt
    25801 tagcgatgcc gtcctcagcg ttagtagata cttactcacg ttttggactg ggaaaagcga
    25861 ccaatttggg gttggtcgga gaacgcagtg gcttatatcc tcaaaaacaa cggtggtctg
    25921 acatagagag ggccaccttc tctttcggct acgggctaat ggtaacaccg ttacagttag
    25981 cgcgagtcta cgcaactatc ggcagctacg gcatttatcg cccactgtcg attaccaaag
    26041 ttgacccccc ggttcccggt gaacgtgtct tcccggaatc cattgttcgc accgtggtgc
    26101 atatgatgga aagcgtggcg ctaccaggcg gcggcggcgt gaaagcggcg attaaaggct
    26161 atcgtatcgc cattaaaacc ggtaccgcga aaaaggtcgg gccggacggt cgctacatca
    26221 ataaatatat tgcttatacc gcaggcgttg cgcctgcgag tcagccgcgc ttcgcgctgg
    26281 ttgttgttct caacgatccg caggcgggta aatactacgg cggcgccgtt tccgcgccgg
    26341 tctttggtgc catcatgggc ggcgtattgc gtaccatgaa catcgagccg gatgcgctga
    26401 caacgggcga taaaaatgaa tttgtgatta atcaaggcga ggggacaggt ggcagatcgt
    26461 aatttgcgcg accttcttgc tccgtgggtg ccagacgcac cttcgcgagc actgcgagag
    26521 atgacactcg acagccgtgt ggctgcggcg ggcgatctct ttgtagctgt agtaggtcat
    26581 caggcggacg ggcgtcgata tatcccgcag gcgatagcgc aaggtgtggc tgccattatt
    26641 gcagaggcga aagatgaggc gaccgacggt gaaatccgtg aaatgcacgg cgtaccggtc
    26701 atctatctca gccagctcaa cgagcgttta tctgcactgg cgggccgctt ttaccatgaa
    26761 ccctctgaca atttacgtct cgtgggcgta acgggcacca acggcaaaac cacgacgacc
    26821 cagctgctgg cgcagtggag ccaactgctt ggcgaaacca gcgcggtaat gggcaccgtt
    26881 ggtaacggcc tgctggggaa agtgatcccg acagaaaata caaccggttc ggcagtcgat
    26941 gttcagcatg agctggcggg gctggtggat cagggcgcga ctttttgcgc aatggaagtt
    27001 tcctcccacg gactggtaca gcaccgtgtg acggcattga aatttgcggc gtcggtcttt
    27061 accaacttaa gccgcgatca ccttgattat catggtgata tggaacacta cgaagccgcg
    27121 aaatggctgc tttattctga gcatcattgc ggtcaggcga ttattaacgc cgacgatgaa
    27181 gtgggccgcc gctggctggc aaaactgccg gacgcggttg cggtatcaat ggaagatcat
    27241 atcaatccga actgtcacgg acgctggttg aaagcgacag aagtgaacta tcacgacagc
    27301 ggtgcgacga ttcgctttag ctcaagctgg ggcgatggcg aaattgaaag ccatctgatg
    27361 ggcgctttta acgtcagcaa cttgctgctg gcgctggcga cgctgctggc gctgggctat
    27421 ccgttggctg acctgctgaa aactgccgca cgcctgcagc cggtttgtgg acgtatggaa
    27481 gtgttcactg cgccaggcaa accgacggta gtggtggatt acgcgcatac accggatgca
    27541 ctggaaaaag ccttacaggc ggcgcgcctg cactgtgcgg gcaagctgtg gtgcgtcttt
    27601 ggctgtggtg gcgatcgtga taaaggcaaa cgtccactga tgggcgcaat tgctgaagag
    27661 ttcgctgacg tggcggtggt gacggacgat aacccgcgta ccgaagaacc gcgtgccatc
    27721 atcaacgata ttctggcggg aatgttagat gccggacatg ccaaagtgat ggaaggccgt
    27781 gctgaagcgg tgacttgcgc cgttatgcag gctaaagaga atgatgtggt actggtcgcg
    27841 ggcaaaggtc atgaggatta ccagattgtt ggcaatcagc gtctggacta ctccgatcgc
    27901 gtcacggtgg cgcgtctgct gggggtgatt gcatgattag cgtaaccctt agccaactta
    27961 ccgatattct caacggtgaa ctaaaagggg cagatatcac ccttgatgct gtaaccacag
    28021 acacacgaaa actgacgccg ggttgcctgt ttgttgccct gaaaggcgaa cgtttcgatg
    28081 cccatgattt tgctgaccag gcgaaagctg gcggagcggg tgcactactg gttaaccgtc
    28141 cgctggatat cgatctgccg caggtaatcg tcaaggatac tcgtctggcg tttggtgaac
    28201 tggctgcatg ggttcgccag caagttccgg cgcgcgtggt tgctctgacc ggttcctccg
    28261 gcaaaacctc cgttaaagag atgacggcag cgattttaag ccagtgtggc aacacgcttt
    28321 atacggcagg caatctcaac aacgacatcg gtgtaccgat gacgctgttg cgcttaacgc
    28381 cagagtacga ttacgcagta attgaacttg gcgcgaacca tcagggcgaa attgcctgga
    28441 ctgtgagtct gactcgcccg gaagcggcgc tggtcaacaa cctggcagcg gcgcatctgg
    28501 aaggttttgg ctcgcttgcg ggtgtcgcga aagcgaaagg tgaaatcttt agcggcctgc
    28561 cggaaaacgg tatcgccatt atgaacgccg acaacaacga ctggctgaac tggcagagcg
    28621 taattggctc acgcaaagtg tggcgtttct cacctaatgc cgccaacagc gatttcaccg
    28681 ccaccaacat ccatgtgact tcgcacggta cggaatttac cctgcaaacc ccaaccggta
    28741 gcgtggatgt tctgctgccg ttgccggggc gtcacaatat tgcgaatgcg ctggcagccg
    28801 ctgcgctctc catgtccgtg ggcgcaacgc ttgatgctat caaagcgggg ctggcaaatc
    28861 tgaaagctgt tccaggccgt ctgttcccca tccaactggc ggaaaaccag ttgctgctcg
    28921 acgactccta taacgccaat gtcggttcaa tgaccgcagc agtccaggta ctggctgaaa
    28981 tgccgggcta ccgcgtgctg gtggtgggcg atatggcgga actgggcgct gaaagcgaag
    29041 cctgccatat acaggtgggc gaagcggcaa aagcagctgg tattgaccgc gtgttaagcg
    29101 tgggcaaaca aagccatgct atcagcactg ccagcggtgt tggcgaacat ttttccgata
    29161 aaactgcgct tatcgcgcgt cttaaatcac tgattgctga gcaacaggta attacgattt
    29221 tagttaaggg ttcacgtagt gctgccatgg aagaggtagt acgcgcttta caggagaatg
    29281 ggacatgtta gtttggctgg ccgaacattt ggtcaaatat tattccggct ttaacgtctt
    29341 ttcctatctg acgtttcgcg ccatcgtcag cctgctgact gcgctgttca tctcattgtg
    29401 gatgggcccg cgcatgattg ctcatttgca aaaactttcc tttggtcagg tggtgcgtaa
    29461 cgacggtcct gaatcacact tcagcaagcg cggtacgccg accatgggcg ggattatgat
    29521 cctgacagcg attgtgatct ccgtactgct gtgggcttac ccgtccaatc cgtacgtctg
    29581 gtgcgtgttg gtagtgctgg taggttacgg tgttattggc tttgttgatg attatcgcaa
    29641 agtagtgcgt aaagacacca aagggttgat cgctcgttgg aagtatttct ggatgtcggt
    29701 cattgcgctg ggtgtcgcct tcgcgctgta ccttgttggc aaagacacgc ccgcaacgca
    29761 gctggtggtc ccatttttta aagatgtgat gccgcaactg gggctgttct acattctgct
    29821 ggcttacttc gtcattgtgg gtactggcaa cgcggtaaac ctgaccgatg gtcttgacgg
    29881 tctggcaatt atgccgaccg tatttgtcgc cggtggtttt gcgctggtgg cgtgggcgac
    29941 cggcaacatg aactttgcca gctatttaca cataccgtat ctgcgacacg ccggggaact
    30001 ggttattgtc tgtaccgcga tagtcggggc aggactgggc ttcctgtggt ttaacaccta
    30061 tccggcgcag gtctttatgg gcgatgtcgg ttcgctggcg ttaggtggtg cgttaggcat
    30121 tatcgccgta ctgctacgtc aggaattcct gctggtgatt atggggggcg tgttcgtggt
    30181 agaaacgctt tctgtcatcc tgcaggtcgg ctcctttaaa ctgcgcggac aacgtatttt
    30241 ccgcatggca ccgattcatc accactatga actgaaaggc tggccggaac cgcgcgtcat
    30301 tgtacgtttc tggattattt cgctgatgct ggtcctgatt ggtctggcaa cgctgaaggt
    30361 acgttaatca tggctgatta ccagggtaaa aatgtcgtca ttatcggcct gggcctcacc
    30421 gggctttctt gcgtggactt tttcctcgct cgcggtgtga cgccgcgcgt tatggatacg
    30481 cgtatgacac cgcctggcct ggataaatta cccgaagctg tagaacgcca cacgggcggt
    30541 ctgaatgatg aatggctgat ggcggccgat ctgattgtcg ccagtcccgg tattgcactg
    30601 gcgcatccat ccttaagcgc tgccgctgat gccggaatcg aaatcgttgg cgatatcgag
    30661 ctgttctgtc gtgaagcaca agcaccgatt gtggcgatca ccggttctaa cggcaaaagc
    30721 acggtcacca cgctagtggg tgaaatggcg aaagcggcgg gggttaacgt tggtgtgggt
    30781 ggcaatattg gcctgcctgc gttgatgctg ctggatgatg agtgcgaact gtacgtgctg
    30841 gagctgtcga gcttccagct tgaaaccacc tccagtttac aggcggtagc agcgaccatt
    30901 ctgaacgtga ctgaagatca tatggatcgc tatccgtttg gtttacaaca gtatcgtgca
    30961 gcaaaactgc gcatttacga aaacgcaaaa atttgcgtgg ttaatgctga tgatgcctta
    31021 acaatgccga ttcgcggtgc ggatgaacgc tgcgtcagct ttggcgtcaa catgggtgac
    31081 tatcacctga atcatcagca gggtgaaacc tggctgcggg tgaaaggcga gaaagtgcta
    31141 aacgtgaaag aaatgaaact ttccgggcag cataactaca ccaatgcact ggcagctctg
    31201 gcactggcag atgccgctgg tttgccgcga gccagcagcc tgaaagcatt aaccacattc
    31261 actggtctgc cgcatcgctt tgaagttgtg ctggagcata acggtgtgcg ctggattaac
    31321 gattcaaaag cgaccaacgt cggcagtacg gaagcggcac tgaatggcct gcacgtagac
    31381 ggcacgctgc atttgttgct gggcggcgat ggtaaatcgg cagattttag cccactggcg
    31441 cgttacctga atggcgataa cgtacgtctg tattgtttcg gtcgggacgg cgcgcagctg
    31501 gcggcgctac gcccggaagt ggcagaacaa accgaaacca tggaacaggc gatgcgcttg
    31561 ctggctccgc gtgttcagcc gggcgatatg gttctgctct ccccggcctg tgccagcctt
    31621 gatcagttca agaactttga acaacgaggc aatgagtttg cccgtctggc gaaggagtta
    31681 ggttgatgcg tttatctctc cctcgcctga aaatgccgcg cctgccagga ttcagtattc
    31741 tggtctggat ctccacggcg ctaaagggct gggtgatggg ctcgcgggaa aaagataccg
    31801 acagcctgat catgtacgat cgcaccttac tgtggctgac cttcggcctc gcggcgattg
    31861 gctttatcat ggtgacctcg gcgtcaatgc ccatagggca acgcttaacc aacgatccgt
    31921 tcttcttcgc gaagcgtgat ggcgtctatc tgatcctggc attcattctg gcgatcatta
    31981 cgctgcgtct gccgatggag ttctggcaac gctacagtgc cacgatgctg ctcggatcta
    32041 tcatcctgct gatgatcgtt ctggtagtgg gtagctcggt taaaggggca tcgcgttgga
    32101 tcgatctcgg tttgctgcgt attcagcctg cggagctgac aaaactgtcg ctgttttgct
    32161 atatcgccaa ctatctggtg cgtaaaggcg acgaagtacg taataacctg cgcggctttc
    32221 tgaaaccgat gggcgtaatt ctggtgttgg cagtgttact gctggcacag ccagaccttg
    32281 gtacggtggt ggtgttgttt gtgactacgc tggcgatgtt gttcctggcg ggagcgaaat
    32341 tgtggcagtt cattgccatt atcggtatgg gcatttcagc ggttgtgttg ctgatcctcg
    32401 ccgaaccgta ccgtatccgc cgtgttaccg cattctggaa tccgtgggaa gatccctttg
    32461 gcagcggcta tcagttaacg caatcgttga tggcgtttgg tcgcggtgaa ctgtggggac
    32521 aaggtttagg taactcggta caaaaactgg agtatctgcc ggaagcgcac actgacttta
    32581 ttttcgccat tatcggcgaa gaactggggt atgtcggtgt ggtgctggca cttttaatgg
    32641 tattcttcgt cgcttttcgc gcgatgtcga ttggccgcaa agcattagaa attgaccacc
    32701 gtttttccgg ttttctcgcc tgttctattg gtatctggtt tagtttccag gcgctggtta
    32761 acgtaggcgc ggcggcgggg atgttaccga ccaaaggtct gacattgccg ctgatcagtt
    32821 acggtggttc gagcttactg attatgtcga cagccatcat gatgctgttg cgtattgatt
    32881 atgaaacgcg tctggagaaa gcgcaggcgt ttgtacgagg ttcacgatga gtggtcaagg
    32941 aaagcgatta atggtgatgg caggcggaac cggtggacat gtattcccgg gactggcggt
    33001 tgcgcaccat ctaatggctc agggttggca agttcgctgg ctggggactg ccgaccgtat
    33061 ggaagcggac ttagtgccaa aacatggcat cgaaattgat ttcattcgta tctctggtct
    33121 gcgtggaaaa ggtataaaag cactgatagc tgcgccgctg cgtatcttca acgcctggcg
    33181 tcaggcgcgg gcgattatga aagcgtacaa acctgacgtg gtgctcggta tgggcggcta
    33241 tgtatcaggt ccaggtggtc tggctgcgtg gtcgttaggc attccggttg tacttcatga
    33301 acaaaacggt attgcgggct taaccaataa atggctggct aagattgcca ccaaagtgat
    33361 gcaggcgttt ccaggcgctt tccctaatgc ggaagtggtg ggtaacccgg tgcgtaccga
    33421 tgtgctggcg ctgccgttgc cgcagcaacg tttggctgga cgtgaaggtc cggttcgtgt
    33481 gttggtagtg ggtggttccc agggcgcacg cattcttaat cagacaatgc cgcaggttgc
    33541 tgcaaaactg ggtgattcag tcactatctg gcatcagagc ggcaaaggtt cgcaacaatc
    33601 cgttgaacag gcgtatgccg aagcgggaca accgcagcat aaagtgacgg aatttattga
    33661 tgatatggcg gcggcgtatg cgtgggcgga tgtcgttgtt tgccgctccg gtgcgttaac
    33721 ggtgagtgaa atcgccgcgg caggacttcc ggcgttgttt gtgccgtttc aacataaaga
    33781 ccgtcagcaa tactggaatg cgctaccgct ggaaaaagcg ggcgcagcca aaattatcga
    33841 gcagtcacag cttagcgtgg atgctgtcgc caacaccctg gccgggtggt cgcgagaaac
    33901 cttattaacc atggcagaac gcgcccgggc tgcatccatt ccggatgcca ccgagcgagt
    33961 ggcaaatgaa gtgagccggg ctgcccgggc gtaattgtag cgatgccttt tgcatcgtat
    34021 gaatttaaga agttaatggc gtaaagaatg aatacacaac aattggcaaa actgcgttcc
    34081 atcgtgcccg aaatgcgtcg cgttcggcac atacattttg tcggcatcgg tggtgccggt
    34141 atgggcggta ttgccgaagt tctggccaat gaaggttatc agatcagtgg ttccgattta
    34201 gcgccaaatc cggtcacgca gcagttaatg aatctgggtg cgacgattta tttcaaccat
    34261 cgcccggaaa acgtacgtga tgccagcgtg gtcgttgttt ccagcgcgat ttctgccgat
    34321 aacccggaaa ttgttgccgc tcatgaagcg cgtattccgg tgatccgtcg tgctgaaatg
    34381 ctggctgagt taatgcgttt tcgtcatggc atcgccattg ccggaacaca cggcaaaacg
    34441 acaaccaccg cgatggtttc cagcatctac gcagaagcgg ggctcgaccc aaccttcgtt
    34501 aacggcgggc tggtaaaagc ggcgggggtt catgcgcgtt tggggcatgg tcggtacctg
    34561 attgccgaag cagatgagag tgatgcatcg ttcctgcatc tgcaaccgat ggtggcgatt
    34621 gtcaccaata tcgaagccga ccacatggat acctaccagg gcgactttga gaatttaaaa
    34681 cagactttta ttaattttct gcacaacctg ccgttttacg gtcgtgcggt gatgtgtgtt
    34741 gatgatccgg tgatccgcga attgttaccg cgtgtgggac gtcagaccac gacttacggc
    34801 ttcagcgaag atgccgacgt gcgtgtagaa gattatcagc agattggccc gcaggggcac
    34861 tttacgctgc tgcgccagga caaagagccg atgcgcgtca ccctgaatgc gccaggtcgt
    34921 cataacgcgc tgaacgccgc agctgcggtt gcggttgcta cggaagaggg cattgacgac
    34981 gaggctattt tgcgtgcgct ggagagcttc caggggactg gtcgccgttt tgatttcctc
    35041 ggtgaattcc cgctggagcc agtgaatggt aaaagcggta cggcgatgtt ggtcgatgac
    35101 tacggccacc acccgacgga agtggacgcc accattaaag cggcgcgtgc aggctggccg
    35161 gataaaaacc tggtaatgct gtttcagccg caccgtttta cccgtacgcg cgacctgtat
    35221 gatgatttcg ccaatgtgct gacgcaggtt gataccctgt tgatgctgga agtgtatccg
    35281 gctggcgaag cgccaattcc gggagcggac agccgttcgc tgtgtcgcac aattcgtgga
    35341 cgtgggaaaa ttgatcccat tctggtgccg gacccggcgc aggtagccga gatgctggca
    35401 ccggtattaa ccggtaacga cctgattctc gttcaggggg ctggtaatat cggaaaaatt
    35461 gcccgttctt tagctgaaat caaactgaag ccgcaaactc cggaggaaga acaacatgac
    35521 tgataaaatc gcggtcctgt tgggcgggac ctccgctgag cgagaagttt ctctgaattc
    35581 tggtgcagcg gtgttagccg ggctgcgtga aggcggtatt gacgcgtatc ctgtcgaccc
    35641 gaaagaagtc gacgtgacgc aactgaagtc gatgggcttt cagaaagtgt ttatcgcgct
    35701 acatggtcgc ggcggtgaag atggcacgct gcagggtatg ctcgagctga tgggcttgcc
    35761 ttataccggc agcggagtga tggcatctgc gctttcaatg gataaactac gcagcaaatt
    35821 gctttggcag ggcgctggtt taccggtagc gccgtgggta gcattaaccc gcgcagagtt
    35881 tgaaaaaggc ctgagcgata agcagttagc agaaatttct gccttaggtt tgccggttat
    35941 cgttaagccg agccgcgaag gttccagtgt gggaatgtca aaagtagtag cagaaaatgc
    36001 tctacaagat gcattaagat tggcatttca gcacgatgaa gaagtattga ttgaaaaatg
    36061 gctaagtggg ccggagttca cggttgcgat actcggtgaa gaaattttac cgtcaatacg
    36121 tattcaaccg tccggaacct tctatgatta tgaggcgaag tatctctctg atgagacaca
    36181 gtatttctgc cccgcaggtc tggaagcgtc acaagaggcc aatttgcagg cattagtgct
    36241 gaaagcatgg acgacgttag gttgcaaagg atggggacgt attgacgtta tgctggacag
    36301 cgatggacag ttttatctgc tggaagccaa tacctcaccg ggtatgacca gccacagcct
    36361 ggtgccgatg gcggcacgtc aggcaggtat gagcttctcg cagttggtag tacgaattct
    36421 ggaactggcg gactaatatg tcgcaggctg ctctgaacac gcgaaacagc gaagaagagg
    36481 tttcttctcg ccgcaataat ggaacgcgtc tggcggggat ccttttcctg ctgaccgttt
    36541 taacgacagt gttggtgagc ggctgggtcg tgttgggctg gatggaagat gcgcaacgcc
    36601 tgccgctctc aaagctggtg ttgaccggtg aacgccatta cacgcgtaat gacgatatcc
    36661 ggcagtcgat cctggcattg ggtgagccag gtacctttat gacccaggat gtcaacatca
    36721 tccagacgca aatagaacaa cgcctgccgt ggattaagca ggtgagcgtc agaaagcagt
    36781 ggcctgatga attgaagatt catctggttg aatatgtgcc gattgcgcgg tggaatgatc
    36841 aacatatggt agacgcggaa ggaaacactt tcagcgtgcc gccagatcgc accagcaagc
    36901 aggtgcttcc aatgctgtat ggcccggaag gcagcgccaa tgaagtgttg cagggctatc
    36961 gcgaaatggg gcagatgctg gcaaaggaca gatttactct gaaggaagcg gcgatgaccg
    37021 cgcggcgttc ctggcagttg acgctgaata acgatattaa gctcaatctt ggccggggcg
    37081 atacgatgaa acgtttggct cgctttgtag aactttatcc ggttttacag cagcaggcgc
    37141 aaaccgatgg caaacggatt agctacgttg atttgcgtta tgactctgga gcggcagtag
    37201 gctgggcgcc cttgccgcca gaggaatcta ctcagcaaca aaatcaggca caggcagaac
    37261 aacaatgatc aaggcgacgg acagaaaact ggtagtagga ctggagattg gtaccgcgaa
    37321 ggttgccgct ttagtagggg aagttctgcc cgacggtatg gtcaatatca ttggcgtggg
    37381 cagctgcccg tcgcgtggta tggataaagg cggggtgaac gacctcgaat ccgtggtcaa
    37441 gtgcgtacaa cgcgccattg accaggcaga attgatggca gattgtcaga tctcttcggt
    37501 atatctggcg ctttctggta agcacatcag ctgccagaat gaaattggta tggtgcctat
    37561 ttctgaagaa gaagtgacgc aagaagatgt ggaaaacgtc gtccataccg cgaaatcggt
    37621 gcgtgtgcgc gatgagcatc gtgtgctgca tgtgatcccg caagagtatg cgattgacta
    37681 tcaggaaggg atcaagaatc cggtaggact ttcgggcgtg cggatgcagg caaaagtgca
    37741 cctgatcaca tgtcacaacg atatggcgaa aaacatcgtc aaagcggttg aacgttgtgg
    37801 gctgaaagtt gaccaactga tatttgccgg actggcatca agttattcgg tattgacgga
    37861 agatgaacgt gaactgggtg tctgcgttgt cgatatcggt ggtggtacaa tggatatcgc
    37921 cgtttatacc ggtggggcat tgcgccacac gaaggtaatt ccttatgctg gcaatgtcgt
    37981 gaccagtgat atcgcttacg cctttggcac accgccaagt gacgccgaag cgattaaagt
    38041 tcgccacggt tgtgcgctgg gttccatcgt tggaaaagat gagagcgtgg aagtgccgag
    38101 cgtaggcggt cgtccaccgc ggagtctgca acgtcagacc ctggcagagg tgatcgagcc
    38161 gcgctatacc gagctgctca atctggtcaa cgaagagata ttgcagttgc aggaaaagct
    38221 tcgccaacaa ggggttaaac atcacctggc ggcaggcatt gtattaaccg gtggcgcagc
    38281 gcagattgaa ggtcttgcag cctgtgctca gcgcgtgttt catacgcagg tgcgtatcgg
    38341 cgcgccgctg aacattaccg gtttaacgga ttatgctcag gagccgtatt attcgacggc
    38401 ggtgggattg cttcattacg ggaaagagtc acatcttaac ggtgaagctg aagtagaaaa
    38461 acgtgttaca gcatcagttg gctcgtggat caagcgactc aatagttggc tgcgaaaaga
    38521 gttttaattt ttatgaggcc gacgatgatt acggcctcag gcgacaggca caaatcggag
    38581 agaaactatg tttgaaccaa tggaacttac caatgacgcg gtgattaaag tcatcggcgt
    38641 cggcggcggc ggcggtaatg ctgttgaaca catggtgcgc gagcgcattg aaggtgttga
    38701 attcttcgcg gtaaataccg atgcacaagc gctgcgtaaa acagcggttg gacagacgat
    38761 tcaaatcggt agcggtatca ccaaaggact gggagctggc gctaatccag aagttggccg
    38821 caatgcggct gatgaggatc gcgatgcact gcgtgcggcg ctggaaggtg cagacatggt
    38881 ctttattgct gcgggtatgg gtggtggtac cggtacaggt gcagcaccag tcgtcgctga
    38941 agtggcaaaa gatttgggta tcctgaccgt tgctgtcgtc actaagccct tcaactttga
    39001 aggcaagaag cgtatggcat tcgcggagca ggggatcact gaactgtcca agcatgtgga
    39061 ctctttgatc actatcccga acgacaaact gctgaaagtt ctgggccgcg gtatctccct
    39121 gctggatgcg tttggcgcag cgaacgatgt actgaaaggt gctgtacaag gtatcgccga
    39181 actgattact cgtccgggtt tgatgaacgt ggactttgca gacgttcgca ccgtaatgtc
    39241 tgaaatgggc tacgcaatga tgggttctgg cgtggcgagc ggtgaagacc gtgcggaaga
    39301 agctgctgaa atggctatct cttctccgct gctggaagat atcgacctgt ctggcgcgcg
    39361 cggcgtgctg gttaacatca cagcgggctt cgacctgcgt ctggatgagt tcgaaacggt
    39421 aggtaacacc atccgtgcat ttgcttccga caacgcgact gtggttatcg gtacttctct
    39481 tgacccggat atgaatgacg agctgcgcgt aactgttgtt gcgacaggta tcggcatgga
    39541 caaacgtcct gaaatcactc tggtgaccaa taagcaggtt cagcagccag tgatggatcg
    39601 ctaccagcag cacgggatgg ctccgctgac ccaggagcag aagccggttg ctaaagtcgt
    39661 gaatgacaat gcgccgcaaa ctgcgaaaga gccggattat ctggatatcc cagcattcct
    39721 gcgtaagcaa gctgattaag aattgactgg aatttgggtt tcgaggctct ttgtgctaaa
    39781 ctggcccgcc gaatgtatag tacacttcgg ttggataggt aatttggcga gataatacga
    39841 tgatcaaaca aaggacactt aaacgtatcg ttcaggcgac gggtgtcggt ttacataccg
    39901 gcaagaaagt caccctgacg ttacgccctg cgccggccaa caccggggtc atctatcgtc
    39961 gcaccgactt gaatccaccg gtagatttcc cggccgatgc caaatctgtg cgtgatacca
    40021 tgctctgtac gtgtctggtc aacgagcatg atgtacggat ttcaaccgta gagcacctca
    40081 atgctgctct cgcgggcttg ggcatcgata acattgttat cgaagttaac gcgccggaaa
    40141 tcccgatcat ggacggcagc gccgctccgt ttgtatacct gctgcttgac gccggtatcg
    40201 acgagctgaa ctgcgccaag aaatttgttc gcatcaaaga gactgttcgt gtcgaagatg
    40261 gcgataagtg ggctgaattt aaaccgtaca atggtttttc gctggatttc accatcgatt
    40321 ttaaccatcc ggctattgat tccagcaacc agcgctatgc gatgaacttc tccgctgatg
    40381 catttatgcg ccagatcagc cgtgcgcgta cgttcggttt catgcgtgat atcgaatatc
    40441 tgcagtcccg tggtttgtgc ctgggcggca gcttcgattg tgccatcgtt gttgacgatt
    40501 atcgcgtact gaacgaagac ggcctgcgtt ttgaagacga atttgtgcgt cacaaaatgc
    40561 tcgatgcgat cggtgacttg ttcatgtgtg gtcacaatat tattggtgca tttaccgctt
    40621 ataaatccgg tcatgcactg aataacaaac tgctgcaggc tgtcctggcg aaacaggaag
    40681 cctgggaata tgtgaccttc caggacgacg cagaactgcc gttggccttc aaagcgcctt
    40741 cagccgtact ggcataacga catttatact gtcgtataaa attcgactgg caaatctggc
    40801 actctctccg gccaggtgaa ccagtcgttt tttttgaatt ttataagagc tataaaaaac
    40861 ggtgcgaacg ctgttttctt aagcactttt acgcacaact tatcttcatt cgtgctgtgg
    40921 acttcaggct ttaatgataa gatttgtgcg ctaaatacgt ttgaatacga tcgggatggc
    40981 aataacgtga gtggaatact gacgcgctgg cgacagtttg gtaaacgcta cttctggccg
    41041 catctcttat tagggatggt cgcggcgagt ttaggtttgc ctgcactcag caatgccgcc
    41101 gaaccaaacg cgcccgcaaa agcgacaacc cgcaaccacg agccttcagc caaagttaac
    41161 tttggtcaat tggccttgct ggaagcgaac acgcgccgcc cgaattcgaa ctattccgtt
    41221 gattactggc atcaacatgc cattcgcacg gtaatccgcc atctttcctt cgcaatggca
    41281 ccgcaaacgc tgcccgttgc tgaagaatct ttgcctcttc aggcgcaaca tcttgcatta
    41341 ctggatacgc tcagcgcgct cctgacccag gaaggcacgc cgtctgaaaa gggttatcgc
    41401 attgattatg cgcattttac cccacaagca aaattcagca cgcccgtctg gataagccag
    41461 gcgcaaggca tccgtgctgg ccctcaacgc ctcagctaac aacaataaac ctttacttca
    41521 ttttattaac tccgcaacgc ggggcgtttg agattttatt atgctaatca aattattaac
    41581 taaagttttc ggtagtcgta acgatcgcac cctgcgccgg atgcgcaaag tggtcaacat
    41641 catcaatgcc atggaaccgg agatggaaaa actctccgac gaagaactga aagggaaaac
    41701 cgcagagttt cgtgcgcgtc tggaaaaagg cgaagtgctg gaaaacttga tcccggaagc
    41761 cttcgctgtg gtgcgtgaag ccagtaagcg tgtttttggt atgcgtcact tcgacgttca
    41821 gttactcggc ggtatggttc ttaacgaacg ctgcatcgcc gaaatgcgta ccggtgaagg
    41881 taaaaccctg accgcaacgc tgcctgctta cctgaacgca ctaaccggta aaggcgtgca
    41941 tgtagttacc gtcaacgact acctggcgca acgtgacgcc gaaaacaacc gtccgctgtt
    42001 tgaattcctt ggcctgactg ttggtatcaa cctgccgggc atgccagcac cggcaaagcg
    42061 tgaagcttac gcagctgaca tcacttacgg tacgaacaac gaatacggct ttgactacct
    42121 gcgcgacaac atggcgttca gtcctgaaga acgtgtacag cgtaaactgc actatgcgct
    42181 ggtggacgaa gtggactcca tcctgatcga tgaagcgcgt acaccgctga tcatttccgg
    42241 cccggcagaa gacagctcgg aaatgtataa acgcgtgaat aaaattattc cgcacctgat
    42301 ccgtcaggaa aaagaagact ccgaaacctt ccagggcgaa ggccacttct cggtggacga
    42361 aaaatctcgc caggtgaacc tgaccgaacg tggtctggtg ctgattgaag aactgctggt
    42421 gaaagaaggc atcatggatg aaggggagtc tctgtactct ccggccaaca tcatgctgat
    42481 gcaccacgta acggcggcgc tgcgcgctca tgcgctgttt acccgagacg tcgactacat
    42541 cgttaaagat ggtgaagtta tcatcgttga cgaacacacc ggtcgtacca tgcagggacg
    42601 tcgttggtcc gatggcctgc atcaggcagt ggaagcgaaa gaaggtgtac agatccagaa
    42661 cgaaaaccag acgctggcgt cgatcacctt ccagaactac ttccgtctgt atgaaaaact
    42721 ggcggggatg actggtactg ctgataccga agctttcgaa ttcagctcca tctacaagct
    42781 ggataccgtc gttgttccga ccaaccgtcc aatgattcgt aaagatctgc cggacctggt
    42841 ctacatgact gaagcggaaa aaattcaggc gatcattgaa gatatcaaag aacgtactgc
    42901 gaaaggccaa ccggtgctgg tgggtactat ctccatcgaa aaatcggagc tggtatcaaa
    42961 cgaactgacc aaagccggta ttaagcacaa cgtcctgaac gccaaattcc acgccaacga
    43021 agcggcgatt gttgctcagg caggttatcc ggctgcggtg actatcgcga ccaacatggc
    43081 gggtcgtggt acagatattg tgctcggtgg tagctggcag gcagaagttg ccgcgctgga
    43141 aaatccgacc gcagagcaaa ttgaaaaaat taaagccgac tggcaggtac gtcacgatgc
    43201 ggtactggca gcaggtggcc tgcatatcat cggtactgaa cgtcacgaat cccgtcgtat
    43261 cgataaccag ttgcgcggtc gttctggtcg tcagggggat gctggttctt cccgtttcta
    43321 cctgtcgatg gaagatgcgc tgatgcgtat ttttgcttcc gaccgagtat ccggcatgat
    43381 gcgtaaactg ggtatgaagc caggcgaagc cattgagcac ccgtgggtga ccaaagcgat
    43441 tgccaacgcc cagcgtaaag ttgaaagccg taacttcgac attcgtaagc aactgctgga
    43501 atatgatgac gtggctaacg atcagcgtcg cgccatttac tcccagcgta acgaactgct
    43561 ggatgtcagc gatgtgagcg aaaccatcaa cagcattcgt gaagatgtgt tcaaagccac
    43621 cattgatgcc tacattccgc cacagtcgct ggaagaaatg tgggatattc cgggactgca
    43681 ggaacgtctg aagaacgatt tcgacctcga tttgccaatt gccgagtggc tggataaaga
    43741 accagaactg catgaagaga cgctgcgtga gcgcattctg gcgcagtcca tcgaagtgta
    43801 tcagcgtaaa gaagaagtgg ttggtgctga gatgatgcgt cacttcgaaa aaggcgtcat
    43861 gctgcaaact ctcgactctc tgtggaaaga gcacctggcg gcgatggact atctgcgtca
    43921 gggtatccac ctgcgtggct atgcacagaa agatccgaag caggaataca aacgtgaatc
    43981 gttctccatg tttgcagcga tgctggagtc gttgaaatat gaagttatca gcacgctgag
    44041 caaagttcag gtacgtatgc ctgaagaggt tgaggagctg gaacaacagc gtcgtatgga
    44101 agccgagcgt ttagcgcaaa tgcagcagct tagccatcag gatgacgact ctgcagctgc
    44161 agctgcactg gcggcgcaaa ccggtgagcg caaagtagga cgtaacgatc cttgcccgtg
    44221 cggttctggt aaaaaataca agcagtgcca tggtcgcctg caataaaagc taacagttga
    44281 agtaaaaggc gcaggattct gcgccttttt tataggttta agacaatgaa aaagctgcaa
    44341 attgcggtag gtattattcg caacgagaac aatgaaatct ttataacccg tcgcgcagca
    44401 gatgcgcaca tggcgaataa actggagttt cccggcggta aaattgaaat gagcgaaacg
    44461 ccggaacagg cggtggtgcg tgaacttcag gaagaggtcg ggattacccc acaacatttt
    44521 tcgctatttg aaaaactgga atatgaattc ccggacaggc atataactct gtggttctgg
    44581 ctggtcgaaa gctgggaagg ggagccgtgg ggtaaagaag ggcaacccgg tgagtggatg
    44641 tcgctggtcg gtctgaatgc cgatgatttt ccgccagcca atgaaccggt acttgcgaag
    44701 cttaagcgtc tgtaggtcag ataagacgtt ttcgccgcat ccgacattcg cacacgatgc
    44761 ctgatgcgac gctgcccgcg tcttatcagg ccagcgtcgc atcagacaaa atgtcactgc
    44821 tttggctctt cgctccagtc atcgctttcg gaaagatcgc cactgctggg gattcgtttt
    44881 tcttcagcag cccattctcc gaggtcgatc agctgacaac gtttggagca aaatggccga
    44941 aacgggctga tttcacccca caccaccgtt ttcccgcagg ttgggcaatt caccgtaata
    45001 gtttctgaca tttttactcc ttagcaacag gccagttcga aatccagacg ttccggtacc
    45061 tgtccgtttt cactgtccag cggcataaaa cgaatggcaa aacggctctt atgaccggaa
    45121 atttgcggat aaagctgtga atcgagtgac agattcaggc gcagcaagtc ggcatcgcca
    45181 ccgttatcct gataaaaacc attcaggctg gtttgtttac ggaagggggc cgactggcga
    45241 attaaatcca gcaccatggt aagtgcctgg gtgagcgggt tcaggctggc aatccaggtt
    45301 tctacctggc tgtcgcgctg cgcctggggt agatgcagcc aaatgtgcaa tgtaggtaaa
    45361 tcaaagctac aacagccgcc tgggatgctc agtcgctgac gcaccagagc aatcaaacga
    45421 tcttcacgca gaaattgccc gatacgcggc gcggaaatta atacgctccc cgccgctttt
    45481 aactgctgaa ttaatgcttc aatacggctc tggtccacgc cgggcacgcc aatccaggtc
    45541 tggagtttac gttgctgccg gtcaagttct ttcaacagct cagtgcggac ttcgccgcgc
    45601 tcgaaaacat ccagtaattc actgacatta cggaagaaat gcagcgcgcc agcgtggtca
    45661 acgatgggta aattaacggt aagttgctga atcaaaaact caatgcgcag ccatgtacgc
    45721 attttttcat ttagtggatg ttcaaaaagg acctgggtct gcattacggt ttttcctgtg
    45781 agacaaactg cgacgcaagc tgcaaatagt gtgcgtgcag gcgggcaaca tccgatgcga
    45841 tagcatccgg tgcgccgtta ttatcaatga cgtcatctgc cacggcaagg cgagcttcgc
    45901 gcggtgcctg ggcagcaagg atttgttcga catgctcgcg agttacatca tcgcgctgca
    45961 tggtgcgctt aagttgcgtt tctgggctga catccaccac cagcactcga ttcgcttttt
    46021 tatacagtga gttttctacc agcaatggca caacccacag tacatagggg gaagttgctt
    46081 gctggatctg gtgttgcgtc tcttgctgaa tcagcggatg cagcagggcg ttaagccagt
    46141 ttttctcttc cgggttggcg aaaatccgct cgcgcaaggc ccggcgctgc aatgttccat
    46201 cagcagcaat tatgttagcg ccaaagtgat cagcaatggc atgtagcgca ggtgcacctg
    46261 gttcaaccac ctgacgcgca ataatatcgg catcaatgac gttaattccg agatcagcaa
    46321 acgcattggc aacggtactc ttgccactgc caatgcctcc cgttaaggca actatatacc
    46381 tcataattta tattcccggg aattcatcat gattatcaaa acgttaaaaa tgagcgcacg
    46441 aaagcgaaat tgatgaaacg ttcgctcact atttaccagg taaatttatg ggattgtagc
    46501 gtaaaaaaag acaatttcgc agtcttgcgc cgcattgatt agtgcgtatg atagcgtcac
    46561 tggagttgcg ctcttaccct tatagccatt aaccccagga atccgcacat gcgtattgaa
    46621 gaagatctga agttaggttt taaagacgtt ctcatccgcc ctaaacgctc cactcttaaa
    46681 agccgttccg atgttgaact ggaacgtcaa ttcaccttca aacattcagg tcagagctgg
    46741 tccggcgtgc cgattatcgc cgcaaatatg gacaccgtag gcacattttc tatggcctct
    46801 gcgctggctt cttttgatat tttgactgct gtgcataaac actattctgt cgaagagtgg
    46861 caagcgttta tcaacaattc ttccgctgat gtgctgaaac atgtgatggt ttctaccggc
    46921 acgtctgatg cggatttcga aaaaactaaa cagattctcg acctgaaccc ggcattaaac
    46981 ttcgtttgta ttgatgtggc gaatggttat tccgaacact tcgtgcagtt cgttgcgaaa
    47041 gcgcgtgaag cgtggccgac caaaaccatt tgtgctggca acgtagtgac tggtgaaatg
    47101 tgtgaggagc ttatcctctc cggtgccgat atcgttaaag ttggcattgg cccaggttct
    47161 gtttgtacaa ctcgcgtcaa aacaggcgtc ggttatccgc aactttctgc ggtgatcgaa
    47221 tgcgccgatg ctgcgcacgg tctgggcgga atgatcgtca gcgatggcgg ctgcaccacg
    47281 ccgggcgatg tcgcgaaagc ctttggcggc ggtgccgatt tcgtcatgct tggcggcatg
    47341 ctggcgggcc acgaagagag cggcggtcgc atcgttgagg agaacggcga gaaatttatg
    47401 ctgttctacg gcatgagctc cgagtctgcg atgaaacgtc acgttggcgg cgttgcggaa
    47461 tatcgcgcag cagaaggtaa aaccgttaag ctgccgctgc gaggcccggt tgaaaatacc
    47521 gcgcgtgata ttttgggcgg cctgcgttca gcttgtacat acgttggggc ttcacgcctg
    47581 aaagagctga ccaagcgcac cacatttatc cgtgtgctgg aacaagaaaa ccgcatcttc
    47641 aacaacctgt aatctcccaa cgctggcgtg gagcaacacg ccagcgttat cccattccac
    47701 tcatcgcatc gcctaaatgg aaaattggca gatacattgc caccaccagc gtaccgataa
    47761 ttcctcccgt tatgatcagc aacgccggtt ccagtaaggc tgcgaggtta tccgccagcg
    47821 ccagtgtgtt atcccgatga tgatgggcga ggttgtctaa catgagatcc agcgagccgg
    47881 atgcctctcc tgttctcact aattgcaaac agagcgggct aaactcaccg gtatttttta
    47941 gcgccagcca gatggggtga ccgttactga tatcgtgctg gatttgtgtc agaagttgca
    48001 cccagtacgg gcagcgcatt gtttctctga cgctctcaac gccctgtaaa aaagtaatgc
    48061 ctgcactttg tgtcagcgcc agaatcgtaa agatctgtgt gagtttttgt ccccgcatca
    48121 gtgaacccat aatcgggatg cgtaacagca atttctgccg tgcgataagc ctggttgggt
    48181 ggcgcatcag cagcttattg gctatcgcca gcagaaagcc gaatagcacc agcaaccaac
    48241 cccattcgcc actaaagctt gccagcgtca tgatcccctg cgttagcgcc ggtagcggag
    48301 tgttaaaggt cttatagata gcggcaaact ccggcagcac aaaatgcagc attgccacaa
    48361 ccaccatgat tgccatcgct aaaatgatga tgggataacg caacgctgat ttcactttat
    48421 cggctaactg gcgctgggct ttttgctgac gcgccagttc aaagcagcat tcatccagct
    48481 taccggttag ttcacccgtg cggatcatcg cctgatagag cggcggaaat acctctgacc
    48541 agggtaataa ggcattggaa aaagcaatgc cctgttcgag atcgagcgcc agtgattgca
    48601 gcaacgcttg ccattgctta ctgggatgct gttccgccag cagtgccagc ccttcagaaa
    48661 gcgttaaccc ggctttgagt agcgtcgcca gttgatgaat gacttccgcg cttttatctc
    48721 ctcgccactg cgcagaattg atggcgattc gcttcaggct aagtggggta accatctgtt
    48781 gctgtagtgc tatgagcagc aaagcacggc tctcagccca tagcatccca tcttgcgcat
    48841 tgccgtcgcc ggttatgcca tgccagcgcc agagttgctt actcgccatg cggcatcccc
    48901 aatacgcgga ttaactcttc aaaggtggtt aagccttgct ccacggccag gcagccgttt
    48961 tcaaaaagcg tacgcatacc cgcctgtcgg gcgtgtgttt ccagcgattc aacgtcggta
    49021 ttagcggaaa taagctggcg tatgatcggt gttatgggta gaacttcaaa taaggccgta
    49081 cgaccataaa aaccgtggta gcaatgtaca caaccgggtg cttgccagtg gggcagcggc
    49141 gacggccata cattgtctgg aatatggatg ggctcctctt gctgtcggcg acaatgtggg
    49201 caaagtttac gtaccagacg ctgggctatt accagcgtaa gtgccgatga gagcatccag
    49261 cgagcaacgc ccatttgctg taaacgcacc agcgtttcgc aggtggaatt ggtgtgtagc
    49321 gtggacaaca ccaggtgacc ggtttgcgcg gcttttatgg caatttctgc cgtttcgcca
    49381 tcgcggatct ctccgatcat gatgacgtca gggtcctggc gcaataacgc acgcaaaacg
    49441 ccctgaaagg taagaccggc acgcgaatgg atttgcgtct ggtttagtcc ggctatgggg
    49501 atctcaaccg gatcttcgac gctacaaata ttaatgtcag cggtattcag cgtttgcagg
    49561 gcactataaa gcgtgaccgt tttgccgctg cctgtagggc cagttaccag caccagtccc
    49621 tgtggttgtt gcaaggcatg agcaaagtcc gccagttgta acggctgcat ccccagcttg
    49681 ttgacatcca gtgcctggct cacctgctgt aacaacctta ataccacctt ttcaccaccc
    49741 cggcatggta aggtcgcaat acgaaatgag acggcgtttc ctgccagttc gacagtgaat
    49801 tgcccgtcct gcggcaggcg atgttccgca atatccagat ttcccagcac ttttaatctg
    49861 gcggttaatg cgactccggc atccggtgaa acgtccggta aaggatgcaa tacgccgtcg
    49921 atacgcaagc ggatgcggta ggcattgtcc gctggttcga tatgaatatc agacgcgcgt
    49981 tgttccagcg cagactgtaa cgttcgagtc agcaactctg ctttgggctg atgcttctcc
    50041 tgaacagcta cgggcaatgt ctgttgtgtg cgactggcgt gaccttccat ttgttggcgc
    50101 gtccagcagg tgatctcaat acgtttggtg gtagcgaaat gcaatgcgtc cagtagctca
    50161 tgcgaaggtg catcgactac cgcaacatga accacctctt cgctggcatc cagcaagact
    50221 ccctgataac gcagacacag ggcggtgagc tgtggaatat tcattgccgc tccttagttg
    50281 gcgtcatcaa agcggaagac atcttcgcag gcttgctgca atgcgctgtc actttgaata
    50341 ttgcagttgc gcgtccagcc ggtgacgccg tttgcgttat cccaacccgg cgtcatgacg
    50401 acgcttagcc cattgagact ttcttgcccg gtcagcgaca ccacgccctt tgccacactc
    50461 atggctgaaa catagcgggt ggtggtaggc gaaggaatgc cattgctgcc accgtcgcag
    50521 gtatttaatc caccatgttc cagcgcgcac aactctacgg cggtacggta aggcacaaag
    50581 gtttgtagca tgtcggtgag tgcggctttg cgcaggtagt tttgataagc gggaatacca
    50641 atggcgctta aaatggcaat gatgccaata accaccatca gttcgataag tgtaaaaccg
    50701 cgttgcttgt ccatttgttt cgctccttga tttggttggc gctactttgg caaacgccat
    50761 cagcacaagc gaggggcaaa aaacgaaacg ggaaagcagc ttccggagtt ttttattacg
    50821 ttgcagcgaa agacaagaaa tttgcgaggc gttacgaaga aagttgggaa aggggagatt
    50881 atccgcccgc gatggagcgg ataaatctgt cagcaatcag caaaaacgca ttgacaggtc
    50941 gagtgcctgt acgtgtttag ttagcgcacc gacggagata aagtccacgc ccgtttcggc
    51001 aaattcgcgc agtgttttgt cagtgacgtt gccagacact tccagtagcg ccttgccgtt
    51061 ggtgcgtttg acggcttcgc gcatctgttc tgtttcgaag ttatccagca tgatgatatc
    51121 ggctcctgct ttcagggctt catcaagttc ttccagattc tctacttcga cttctactgg
    51181 cgcatctgga tgcagccagg atgctttttc gaccgcctgg cgcactgagc cggaggcaat
    51241 aatatggttt tctttgatca ggaaggcatc agaaagcccc agacggtgat tcgctccgcc
    51301 gccgcaaagt accgcgtatt tcagagctga acgcaggccg ggtaaggttt tgcgcgtatc
    51361 caacagctgc gtgttggtgc cttccagtaa ttcgacatag tggcgtacct tactggcaac
    51421 tcctgaaagg gtttgcacaa aattaagcgc agtgcgttcg cccgttaaca gcacgcgaga
    51481 tgggccttca agttcgaaca agggttgatt ggcgttgatg acatcgccgt catccacatg
    51541 ccagattatg gtgacatcgt cgcctgccag ttgaataaac acctcttcaa cccagcgttt
    51601 gccgcaaaat acgccattct cgcgggtgat cactgtggca tgagagcgag agttttccgg
    51661 taaaagtttt gccgtaatgt cattgttggc atcgactgtt ccgcctaaat cttcccgcag
    51721 cgcctgggcc accgcgccgg ggatatcgag attaatgcgt tccagcagct cgtcacgtcg
    51781 ggtgtcaggg ttatagcggc gaggcggcat gttaaaactc cagatagcta acgaatcata
    51841 aggtagaaac atgctactct gaaccgggta ttagcaccac atataaggag atcctgcatg
    51901 ttgttagaac aggggtggct ggctggcgcg cgccgcgttc cctcaccaca ttacgattgc
    51961 cgcccggatg acgaaacacc caccctgctg gtggtgcaca atattagcct gccgccaggc
    52021 gagtttggcg gtccgtggat cgacgcatta ttcactggaa ctattgatcc gcaggcacat
    52081 cctttctttg ctgagatcgc ccatttgcgc gtctccgctc actgtttgat tcgccgcgat
    52141 ggtgaaatag tccagtatgt tcctttcgat aaacgtgcct ggcatgccgg agtctctcag
    52201 tatcaggggc gcgaacgctg caatgatttt tctattggga ttgagctgga aggcaccgat
    52261 acgctggcgt ataccgatgc gcagtatcaa cagcttgcgg cggttacgcg ggcactgatt
    52321 gatcgctatc cggatatcgc taataacatg acgggccatt gtgatattgc gccggatcgg
    52381 aaaaccgatc ccggtcctgc atttgattgg gcacggtttc gtgcactgat cagcaaggag
    52441 acaacatgac gctatttaca accttactgg tgttaatttt cgagcgcctg tttaagttgg
    52501 gcgagcactg gcagcttgat catcgtcttg aagcgttctt tcggcgggtg aaacattttt
    52561 ctctcgggcg cacattaggc atgaccatta ttgcgatggg cgtgactttt ttactgttac
    52621 gcacattgca gggagtatta ttcaacgttc ccacgctgct ggtgtggctg ctgattggtt
    52681 tgctgtgtat tggcgcaggt aaagttcgtc ttcattatca tgcttatctg acagctgctt
    52741 cacgtaatga tagccatgcc cgtgccacga tggctggcga actcaccatg attcacggcg
    52801 tcccggcagg ctgcgatgaa cgtgagtatt tgcgtgagct gcaaaatgca ttgctgtgga
    52861 ttaactttcg tttttatctt gcaccgctgt tctggctgat tgtgggggga acctggggac
    52921 ccgttacgct gatggggtat gcgtttttgc gtgcatggca atactggctg gcgcgttacc
    52981 agacgccgca tcatcgttta cagtccggca ttgatgccgt gcttcatgta ctggattggg
    53041 tgccggttcg tcttgcgggt gtggtatatg ccttgatcgg tcatggggag aaagcgttac
    53101 cggcctggtt tgcttcgctg ggtgatttcc atacttcgca atatcaggta ttaacgcgtc
    53161 tggcgcagtt ctctctggcg cgtgaaccgc atgtcgataa ggtggagacg ccgaaggcag
    53221 cggtttccat ggcgaagaaa acctcgttcg tggtcgtggt ggtaattgcg ctactgacga
    53281 tttacggggc gttggtgtaa agattattgc cctcaccctg cacgggtgag ggcgtagaga
    53341 gattaatgcg cttttacggc tttggcggtt ttctctttaa acagatagcc gatacctaac
    53401 acgatcagcc ataccgggat caggtatacc gaaatcgcca ttcctggggt catcagcata
    53461 atcaccaata ccgccgccat aaacagcagg cagatccagt tacccagcgg ataaagcaga
    53521 gcagggaagc gagttaccac gccttgttcc tgcttggcgc gacggaattt catatgcgcc
    53581 aggctaatca tcgcccagtt gatgaccagt gcagatacca ccagcgccat taacaggccg
    53641 aatgcggatt ccggtgcaag gtagttaatc agcacgcaca atgccgtaac cagcgcagac
    53701 accagaatag tattaaccgg tacaccgcgt ttgtcgacag acgccagcgc ttttggcgcg
    53761 ttgccctgtt gtgccagacc aaacagcata cggctgttgc aatatacgca gctgttgtac
    53821 acggagagcg ccgcagtcag taccacgatg ttcagcgcat ttgccacaaa ggtatcgcct
    53881 aactcgtgga agatcagcac aaacgggctg gtgtcagcgg taacgcgtgt ccacggcatc
    53941 agtgagagca gaacggctaa cgaaccaatg tagaaaatca ggatgcggta gataacctgg
    54001 ttagtcgctt ttggaatact ttgctccggg ttatctgctt ctgctgcggt gatgcccacc
    54061 agttccagac caccgaaaga gaacatgata atcgccatca tcatcaccag cccggtgaag
    54121 ccgtgcggca ggaaaccacc ctgatcccac aggttgctaa cggtcgcctg cgggccgccg
    54181 ttgccactga atagcagcca gccgccgaag atgatcatcg ctaccaccgc gataactttg
    54241 ataatggcaa accagaactc catctcgcca aacactttta cgtttgtcag gttgatggcg
    54301 ttgatcacca caaagaacac ggcggcagaa acccaggtgg ggatttccgg ataccagaac
    54361 tgaatgtatt tacccacggc agtcagctct gccatggcaa ctaaaacgta cagtacccag
    54421 tagttccagc cagaggcgaa accggcaaaa ctgccccagt atttataagc aaagtggcta
    54481 aaggagcctg cgacaggttc ttcgaccacc atttcaccta gctgacgcat gatcagaaag
    54541 gcgataaaac cagcaatggc gtaacccagg ataatccctg gccctgcaga ctgtattacg
    54601 gaggcgctac ccaggaatag cccggtccct atcgcgccac ccagcgcgat aagctgaata
    54661 tggcggtttt taaggccgcg ctttagctgc tcgccgtgct gttgaccttc catcatgaaa
    54721 cctcgtgcgg tgattgtttt tttgatctac gcagtgatgc gtgtgtaagt ttgcaattcc
    54781 gtttgttgta ttaatttgtt tacatcaaag aagtttgaat tgttacaaaa agacttccgt
    54841 cagatcaaga ataatggtat gtgacagcga atgcacccgc tttatgcatg gttgaagatg
    54901 agttgcttaa aaagaaaccg tttgtaaagc tcagcctcaa cccctctcaa tatgcagaat
    54961 gaatttaaat tcgttttaat tgaattaaaa atcacaaaat tggtaagtga atcggttcaa
    55021 ttcggatttt tatagtttaa taatcgttaa aaaatccctt tcctacgtaa agtctacatt
    55081 tgtgcatagt tacaactttg aaacgttata tatgtcaagt tgttaaaatg tgcacagttt
    55141 catgatttca atcaaaacct gtatggacat aaggtgaata ctttgttact ttagcgtcac
    55201 agacatgaaa ttggtaagac caattgactt cggcaagtgg cttaagacag gaactcatgg
    55261 cctacagcaa aatccgccaa ccaaaactct ccgatgtgat tgagcagcaa ctggagtttt
    55321 tgatcctcga aggcactctc cgcccgggcg aaaaactccc accggaacgc gaactggcaa
    55381 aacagtttga cgtctcccgt ccctcattgc gtgaggcgat tcaacgtctc gaagcgaagg
    55441 gcttgttgct tcgtcgccag ggtggcggca cttttgtcca gagcagccta tggcaaagct
    55501 tcagcgatcc gctggtggag ctgctctccg accatcctga atcacagtat gacttgctcg
    55561 aaacacgaca cgccctggaa ggtatcgccg cttattacgc cgcgctgcgt agtaccgatg
    55621 aagacaagga acgcatccgt gaactccacc acgctataga gctggcgcag cagtctggcg
    55681 atctggacgc ggaatcaaac gccgtactcc agtatcagat tgccgtcacc gaagcggccc
    55741 acaatgtggt tctgcttcat ctgctaaggt gtatggagcc gatgttggcc cagaatgtcc
    55801 gccagaactt cgaattgctc tattcgcgtc gcgagatgct gccgctggtg agtagtcacc
    55861 gcacccgcat atttgaagcg attatggccg gtaagccgga agaagcgcgc gaagcatcgc
    55921 atcgccatct ggcctttatc gaagaaattt tgctcgacag aagccgtgaa gagagccgcc
    55981 gtgagcgttc tctgcgtcgt ctggagcaac gaaagaatta gtgatttttc tggtaaaaat
    56041 tatccagaag atgttgtaaa tcaagcgcat ataaaagcgc ggcaactaaa cgtagaacct
    56101 gtcttattga gctttccggc gagagttcaa tgggacaggt tccagaaaac tcaacgttat
    56161 tagatagata aggaataacc catgtcagaa cgtttcccaa atgacgtgga tccgatcgaa
    56221 actcgcgact ggctccaggc gatcgaatcg gtcatccgtg aagaaggtgt tgagcgtgct
    56281 cagtatctga tcgaccaact gcttgctgaa gcccgcaaag gcggtgtcaa cgtagccgca
    56341 ggcaccggta tcagcaacta catcaacacc atccccgttg aagaacaacc ggagtatccg
    56401 ggtaatctgg aactggaacg ccgtattcgt tcagctatcc gctggaacgc catcatgacg
    56461 gttctgcgtg cgtcgaaaaa agacctcgaa ctgggcggcc acatggcgtc cttccagtct
    56521 tccgcaacca tttatgatgt gtgctttaac cacttcttcc gtgcacgcaa cgagcaggat
    56581 ggcggcgacc tggtttactt ccagggccac atctccccgg gcgtttacgc tcgtgctttc
    56641 ctggaaggtc gtctgactca ggagcagctg gataacttcc gtcaggaagt tcacggcaat
    56701 ggcctctctt cctatccgca cccgaaactg atgccggaat tctggcagtt cccgaccgta
    56761 tctatgggtc tgggtccgat tggtgctatt taccaggcta aattcctgaa atatctggaa
    56821 caccgtggcc tgaaagatac ctctaaacag accgtttacg cgttcctcgg cgacggtgaa
    56881 atggacgaac cggaatccaa aggtgcgatc accatcgcta ctcgtgaaaa actggataac
    56941 ctggtcttcg ttatcaactg taacctgcag cgtcttgacg gcccggtcac cggtaacggc
    57001 aagatcatca acgaactgga aggcatcttc gaaggtgctg gctggaacgt gatcaaagtg
    57061 atgtggggta gccgttggga tgaactgctg cgtaaagata ccagcggtaa actgatccag
    57121 ctgatgaacg aaaccgttga cggcgactac cagaccttca aatcgaaaga tggtgcgtac
    57181 gttcgtgaac acttcttcgg taaatatcct gaaaccgcag cactggttgc agactggact
    57241 gacgagcaga tctgggcact gaaccgtggt ggtcacgatc cgaagaaaat ctacgctgca
    57301 ttcaagaaag cgcaggaaac caaaggcaaa gcgacagtaa tccttgctca taccattaaa
    57361 ggttacggca tgggcgacgc ggctgaaggt aaaaacatcg cgcaccaggt taagaaaatg
    57421 aacatggacg gcgtgcgtca catccgcgac cgtttcaatg tgccggtgtc tgatgcagat
    57481 atcgaaaaac tgccgtacat caccttcccg gaaggttctg aagagcatac ctatctgcac
    57541 gctcagcgtc agaaactgca cggttatctg ccaagccgtc agccgaactt caccgagaag
    57601 cttgagctgc cgagcctgca agacttcggc gcgctgctgg aagagcagag caaagagatc
    57661 tctaccacta tcgctttcgt tcgtgccctg aacgtaatgc tgaagaacaa gtcgatcaaa
    57721 gaccgactgg tgccgatcat cgccgacgaa gcgcgtactt tcggtatgga aggtctgttc
    57781 cgtcagattg gtatttacag cccgaacggt cagcagtaca ccccgcagga ccgcgagcag
    57841 gttgcttact ataaagaaga cgagaaaggt cagattctgc aggaagggat caacgagctg
    57901 ggcgctgggt gttcctggct ggcagcggcg acctcttaca gcaccaacaa tctgccgatg
    57961 attccgttct acatctatta ctcgatgttc ggcttccagc gtatcggcga tctgtgctgg
    58021 gcggctggtg accagcaagc gcgtggcttc ctgatcggcg gtacttccgg tcgtaccacc
    58081 ctgaacggcg aaggtctgca gcacgaagat ggtcacagcc acattcagtc gctgactatc
    58141 ccgaactgta tctcttacga cccggcttac gcttacgaag ttgctgtcat catgcatgac
    58201 ggtctggagc gtatgtacgg tgaaaaacaa gagaacgttt actactacat cactacgctg
    58261 aacgaaaact accacatgcc ggcaatgccg gaaggtgctg aggaaggtat ccgtaaaggt
    58321 atctacaaac tcgaaaccat tgaaggtagc aaaggtaaag ttcagctgct gggctccggt
    58381 tctatcctgc gtcacgtccg tgaagcggca gagatcctgg cgaaagacta cggcgtaggt
    58441 tctgacgttt atagcgtgac ctcattcacc gaactggcgc gtgatggtca ggattgtgaa
    58501 cgctggaaca tgctgcaccc gctggaaact ccgcgcgttc cgtatatcgc tcaggtgatg
    58561 aatgacgctc cggcagtggc atctaccgac tatatgaaac tgttcgctga gcaggtccgt
    58621 acttacgtac cggctgacga ctaccgcgta ctgggtactg atggcttcgg tcgttccgac
    58681 agccgtgaga acctgcgtca ccacttcgaa gttgatgctt cttatgtcgt ggttgcggcg
    58741 ctgggcgaac tggctaaacg tggcgaaatc gataagaaag tggttgctga cgcaatcgcc
    58801 aaattcaaca tcgatgcaga taaagttaac ccgcgtctgg cgtaagaggt aaaagaataa
    58861 tggctatcga aatcaaagta ccggacatcg gggctgatga agttgaaatc accgagatcc
    58921 tggtcaaagt gggcgacaaa gttgaagccg aacagtcgct gatcaccgta gaaggcgaca
    58981 aagcctctat ggaagttccg tctccgcagg cgggtatcgt taaagagatc aaagtctctg
    59041 ttggcgataa aacccagacc ggcgcactga ttatgatttt cgattccgcc gacggtgcag
    59101 cagacgctgc acctgctcag gcagaagaga agaaagaagc agctccggca gcagcaccag
    59161 cggctgccgc ggcaaaagac gttaacgttc cggatatcgg cagcgacgaa gttgaagtga
    59221 ccgaaatcct ggtgaaagtt ggcgataaag ttgaagctga acagtcgctg atcaccgtag
    59281 aaggcgacaa ggcttctatg gaagttccgg ctccgtttgc tggcaccgtg aaagagatca
    59341 aagtgaacgt gggtgacaaa gtgtctaccg gctcgctgat tatggtcttc gaagtcgcgg
    59401 gtgaagcagg cgcggcagct ccggcggcta aacaggaagc agctccggca gcggcctctg
    59461 catcagcagc tggcgtgaaa gaagttaacg ttccggatat cggcggtgac gaagttgaag
    59521 tgaccgaagt gatggtgaaa gtgggcgaca aagttgccgc tgaacagtca ctgatcaccg
    59581 tagaaggcga taaagcttct atggaagttc cggctccgtt tgcaggcgtc gtgaaggaac
    59641 tgaaagtcaa cgttggcgat aaagtgaaaa ctggctcgct gattatgatc ttcgaagttg
    59701 aaggcgcagc gcctgcggca gctcctgcga aacaggaagc ggcagcgccg gctccggcag
    59761 caaaagctga agctccggca gcagctccgg ctgcgaaagc ggaaggcaaa tctgaatttg
    59821 ctgaaaacga cgcttacgtt cacgcgactc cgctgatccg ccgtctggca cgcgagtttg
    59881 gcgttaacct ggcgaaagtg aagggcactg gccgtaaagg tcgtatcctg cgcgaagacg
    59941 ttcaggctta cgtgaaagaa gctatcaaac gtgcagaagc ggctccggcg gtgactggcg
    60001 gcggtatccc aggcatgctg ccgtggccga aagtggactt cagcaagttt ggtgaaatcg
    60061 aagaagtgga actgggccgt atccagaaaa tttctggtgc gaacctgagc cgtaactggg
    60121 tgatgatccc gcatgttacc cacttcgaca aaaccgatat caccgagctg gaagcgttcc
    60181 gtaaacagca gaacgaagaa gcggcgaaac gtaagctgga tgtgaagata accccagttg
    60241 tcttcatcat gaaagccgtt gctgcagctc ttgagcagat gcctcgcttc aacagttcgc
    60301 tgtcggaaga cggtcagcgt ctgaccctga agaaatacat caacatcggt gtggcggtgg
    60361 ataccccgaa cggtctggtt gttccggtat tcaaagacgt caacaagaaa ggcatcatcg
    60421 agctgtctcg cgagctgatg actatttcta agaaagcgcg tgacggtaag ctgactgcgg
    60481 gcgaaatgca gggcggttgc ttcaccatct ccagcatcgg cggcctgggt actacccact
    60541 tcgcgccgat tgtgaacgcg ccggaagtgg ctatcctcgg cgtttccaag tccgcgatgg
    60601 agccggtgtg gaatggtaaa gagttcgtgc cgcgtctgat gctgccgatt tctctctcct
    60661 tcgaccaccg cgtgatcgac ggtgctgatg gtgcccgttt cattaccatc attaacaaca
    60721 cgctgtctga cattcgccgt ctggtgatgt aagtaaaaga gccggcccaa cggccggctt
    60781 ttttctggta atctcatgaa tgtattgagg ttattagcga atagacaaat cggttgccgt
    60841 ttgttgttta aaaattgtta acaattttgt aaaataccga cggatagaac gacccggtgg
    60901 ataatgggcg tcataaaaaa aacgtcagac ccgccggaga taaatatata gaggtcatga
    60961 tgagtactga aatcaaaact caggtcgtgg tacttggggc aggccccgca ggttactccg
    61021 ctgccttccg ttgcgctgat ttaggtctgg aaaccgtaat cgtagaacgt tacaacaccc
    61081 ttggcggtgt ttgcctgaac gtcggctgta tcccttctaa agcactgctg cacgtagcaa
    61141 aagttatcga agaagccaaa gcgctggctg aacacggcat cgtcttcggc gaaccgaaaa
    61201 ccgatatcga caagattcgt acctggaaag agaaagtgat caatcagctg accggtggtc
    61261 tggctggtat ggcgaaaggc cgcaaagtca aagtggtcaa cggtctgggt aaatttaccg
    61321 gggctaacac cctggaagtt gaaggtgaga acggcaaaac cgtgatcaac ttcgacaacg
    61381 cgatcattgc agcgggttct cgcccgatcc aactgccgtt tattccgcat gaagatccgc
    61441 gtatctggga ctccactgac gcgctggaac tgaaagaagt accagaacgc ctgctggtaa
    61501 tgggtggcgg tatcatcggt ctggagatgg ggaccgtata ccacgcgctg ggttcacaga
    61561 ttgacgtggt tgaaatgttc gaccaggtta tcccggcagc tgacaaagac atcgttaaag
    61621 tctttaccaa gcgtatcagc aagaaattca acctgatgct ggaaaccaaa gttaccgccg
    61681 ttgaagcgaa agaagacggt atttatgtga cgatggaagg caaaaaagca ccagctgaac
    61741 cgcagcgtta cgacgccgtg ctggtagcga ttggtcgtgt gccgaacggt aaaaacctcg
    61801 acgcaggcaa agctggcgtg gaagttgacg accgtggttt catccgcgtt gacaaacagc
    61861 tgcgtactaa cgtaccgcac atctttgcta tcggcgatat tgtcggtcag ccgatgctgg
    61921 cacataaagg tgttcacgaa ggtcacgttg ccgctgaagt tatcgccggt aaaaaacatt
    61981 acttcgatcc gaaagttatc ccgtccatcg cctataccga accagaagtt gcatgggtag
    62041 gtctgactga gaaagaagcg aaagagaaag gcatcagcta cgaaactgcc accttcccgt
    62101 gggctgcttc tggtcgtgct atcgcttccg actgcgcaga cggtatgacc aagctgattt
    62161 tcgacaaaga atctcaccgt gtgatcggtg gtgcgattgt cggtactaac ggcggcgagc
    62221 tgctgggtga aatcggtctg gcaatcgaaa tgggttgtga tgctgaagac atcgcactga
    62281 ccatccacgc gcacccgact ctgcacgagt ctgtgggcct ggcggcagaa gtgttcgaag
    62341 gtagcattac cgacctgccg aacccgaaag cgaagaagaa gtaatttttc gtttgccgga
    62401 acatccggca attaaaaaag cggctagcca cgccgctttt tttacgtctg taatttacct
    62461 ttccagtcgc cttgctccgc gctcagagag acgttcgcgt actgctgacc gttgctcgtt
    62521 attcagcctg acagtatggt tactgtcgtt tagacgttgt gggcggctct cctgaacttt
    62581 ctcccgaaaa acctgacgtt gttcaggtga tgccgattgt atacgctggc gggcgttatc
    62641 acgttgctgt tggttcagtg ggcgctgctg tactttttcc ttaaacacct ggcgctgttc
    62701 gggagttgca gactgaatgc gctggcgcgc tgcctctctt cgctgctggt tctgcgggtt
    62761 agtctgcatt ttctcgcgaa ccgcctggcg ctgctcaggc gaggcggact gaatacgctc
    62821 acgcgctgcc tctcttcgct gctggatctg cgggttagtc tgcattttct cgcggactgc
    62881 ctggcgctgc tcaggagagg ccgactgata acgctgacga gcggcgtcct tttgttgctg
    62941 ggtcagtggt tggcgacggc tgaagtcgcg gaagtcgtca tagctcccat agttttcagc
    63001 ttcattaaac cgctgtgccg cagcctgacg ctgggtatct cgcgtagtga ctggtgctgc
    63061 gtgtgttcgt tgctgaaact ggcttgctgc cgcctgacgc tgactgtcgc gcgatagagc
    63121 aggtaactgc gtggcgctca tgccgccgtt gacatcggtt tggtgaaacc gctttgccat
    63181 atcctgatca tgatagggca caccatcacg gtagtttgga ttgtgccgcc atgccatatt
    63241 cttatcagta agatgctcac cagtgatacg gttgaaattg ttgacgtcga tattgatgtt
    63301 gtcgccgttg tgttgccagt cattaccgtc acgatgaccg ccatcgtggt ggtgataatc
    63361 atcatcgtca tgatgatgat ggtcatgatc gtcatcgtcc cagtcgatgc tgctgaatag
    63421 tgcgtatgtg gtagcaacgc ccatgctata gccgaatccg cgcacaaagc tgtcaacaaa
    63481 cggttctccg gctggcggcg gcagataaac tggcggatac gcagtattgg cccagttccc
    63541 gtaaaccacg gttgggttgt agttgggaat atagaccaca tcaggattgg tgggctcaat
    63601 ggaaatgacg gttgttgcag gctctgtaat gacagggttg gcagttgaaa cggtattgga
    63661 tggtatgacg ggagccgtga ctgtctgtgt taccggtaca gctttcttcg ttgtggtaat
    63721 aactttctgt tcggttgatg acttcagcga accggtttgt tgcgccagtt gccgcaatcg
    63781 ctgtaccgag tccatcacgt cctgcggctg cgccagaaaa gcatcgccca ggttttgcac
    63841 ccattgcggg ttttcgccca tcaacgccat caactgtgga aaggccacca gtgatttgac
    63901 gctggcgtcc cacggctggt cagataccgc ctgaatagca gcatcgcctt gtttaagtgg
    63961 attatcgtgc gaccattgca ctgcttgagc aacgtttgcc ggataggttg atgccattaa
    64021 cacttgtgaa agcagagagt cggggtatag cgcgacaggt gcaacccatt gatctatttg
    64081 agcagtgctg aatgcggatt tgacgacggc aggtgttaca ggaggcacgg aaaccgttgc
    64141 aggaagcgta accgcggcag cgtcagacac agccagttgt gtcgattgcg cttccacagg
    64201 cgcttccact gtgcggcttt ttatatatag cccggcagag gcggcacaaa gcccggcact
    64261 gcaaattagc gccagcacat ggggtttaaa cggcaaagtc attttcataa ttcggatctc
    64321 aaggaaatcg caatggtcgg cgaactgcca cccgcaggtg ctgtgattcc gagtataaag
    64381 aggcggtagt ttaaattttg actaatcttg ggattcgttg agaaaggtga ttatcaccat
    64441 gcgaattaac gaagttttta cggagggaaa cattctctag accatcctta acgattcagc
    64501 cactttttta tgttgctttt ttgtaaacag attaacacat cgtcaaaatc ctgctattct
    64561 gcccgttgcg gtactgggca tttaccctac aaactgctgt ctcacaggag cgtgaagaga
    64621 atcgcctgcc gcactatgac aatgagagcg aggagaaccg tcgtgctaga agaataccgt
    64681 aagcacgtag ctgagcgtgc cgctgagggg attgcgccca aacccctgga tgcaaaccaa
    64741 atggccgcac ttgtagagct gctgaaaaac ccgcccgcgg gcgaagaaga attcctgtta
    64801 gatctgttaa ccaaccgtgt tccccctggc gtcgatgaag ccgcctatgt caaagcaggc
    64861 ttcctggctg ctgtcgccaa aggcgaagcc aaatccccac tgctgactcc ggaaaaagcc
    64921 atcgaactgc tgggcaccat gcaggggggt tataatattc atccgctgat cgacgcgctg
    64981 gatgatgcca aactggcacc gatcgctgcc aaagcacttt ctcacacgct gctgatgttc
    65041 gataacttct atgacgtaga agagaaagcg aaagcaggca acgaatatgc gaagcaggta
    65101 atgcagtcct gggcggatgc cgaatggttc ctgaatcgcc cggcgctggc tgaaaaactg
    65161 accgttaccg tcttcaaagt cactggcgaa accaacaccg atgacctctc tccggcacca
    65221 gatgcgtggt cgcgcccgga tatcccactg cacgcgctgg cgatgctgaa aaacgcccgt
    65281 gaaggtattg agccagatca gcctggtgtt gttggtccga tcaaacagat tgaagctctg
    65341 caacagaaag gtttcccgct ggcgtacgtc ggtgacgttg tgggtacggg ttcatcgcgt
    65401 aaatccgcca cgaactccgt gctgtggttt atgggcgatg atattccaca tgtgccgaac
    65461 aaacgcggcg gtggtttgtg cctcggcggt aaaattgcac ccatcttctt taacacgatg
    65521 gaagatgcgg gtgcactgcc aatcgaagtc gacgtctcta acctgaacat gggcgacgta
    65581 attgacgttt acccgtacaa aggtgaagtg cgtaaccacg aaaccggcga actgctggca
    65641 accttcgaac tgaaaaccga cgtgctgatt gatgaagtgc gtgctggcgg ccgtattccg
    65701 ctgattatcg ggcgtggcct gaccaccaaa gcgcgtgaag cacttggcct gccgcacagc
    65761 gatgtgttcc gtcaggcgaa agatgtcgct gagagcgacc gtggcttctc gctggcgcag
    65821 aaaatggtgg gccgtgcctg tggcgtgaaa ggcattcgtc cgggcgcgta ctgcgaaccg
    65881 aaaatgactt ctgtaggttc acaggacacc accggcccga tgacccgtga tgaactgaaa
    65941 gacctggcgt gcctgggctt ctcggctgac ctggtgatgc agtctttctg ccacaccgcg
    66001 gcgtatccga aaccggttga cgttaacact caccacaccc tgccggactt cattatgaac
    66061 cgtggcggtg tgtcgctgcg tccgggtgac ggcgtaatcc actcctggct gaaccgtatg
    66121 ctgctgccgg ataccgtcgg tactggcggt gactcccata cccgtttccc gatcggtatc
    66181 tctttcccgg cgggttctgg tctggtggca tttgcagccg caacaggcgt aatgccgctg
    66241 gatatgccgg aatctgttct ggtgcgcttc aaaggcaaaa tgcagccggg catcaccctg
    66301 cgcgatctgg tacacgctat tccgctgtat gcgatcaaac aaggtctgct gaccgttgag
    66361 aagaaaggca agaaaaacat cttctcaggt cgcattctgg aaattgaagg tctgccggat
    66421 ctgaaagttg agcaggcctt tgagctgacc gatgcgtccg ccgagcgttc tgctgccggt
    66481 tgtaccatca agctgaacaa agaaccgatc atcgaatacc tgaactctaa catcgtcctg
    66541 ctgaagtgga tgatcgcgga aggttacggc gatcgtcgta ccctggaacg tcgtattcag
    66601 ggcatggaaa aatggctggc gaatcctgag ctgctggaag ccgatgcaga tgcggaatac
    66661 gcggcagtga tcgacatcga tctggcggat attaaagagc caatcctgtg tgcaccgaac
    66721 gacccggacg acgctcgtcc gctgtctgcg gtacagggcg agaagatcga cgaagtgttt
    66781 atcggttctt gcatgactaa catcggtcac ttccgtgctg cgggtaaact gctggatgcg
    66841 cacaaaggtc agttgccgac ccgcctgtgg gtagcaccgc caacccgtat ggacgccgcg
    66901 cagttgaccg aagaaggcta ctacagcgtc ttcggtaaga gtggtgcgcg tatcgagatc
    66961 cctggctgtt ccctgtgtat gggtaaccag gcgcgtgtag cagacggtgc gacggtggtt
    67021 tccacctcta cccgtaactt cccgaaccgt ctggggactg gcgcgaatgt cttcctggct
    67081 tctgctgaac tggctgctgt tgcggcgctg attggcaaac tgccgacgcc ggaagagtac
    67141 cagacctacg tggcgcaagt agataaaact gccgttgata cttaccgtta tctgaacttc
    67201 aaccagcttt ctcagtacac cgaaaaagcg gacggggtga ttttccagac tgcggtttaa
    67261 taagtaagcg cacgcgctgc gcataaacga cacaatgccc ggtgaatgag attcccgggc
    67321 atttttttat ttctaaacca tcgccgttcc gctgtttttc tccggtaagg ctgcgataat
    67381 tacatcaatg gcgcaatgcg atttcggcgc attgccggga gcagaggaac acactatgga
    67441 ttacgaattt ctgcgcgata ttaccggagt ggtaaaggtg cgcatgtcca tggggcatga
    67501 agtggtcggg cactggttta atgaagaggt gaaagaaaac ctggccttgc ttgatgaagt
    67561 ggaacaagcg gcgcacgcat tgaaaggtag tgaacgatcc tggcaacggg cagggcatga
    67621 atacactctg tggatggacg gtgaagaggt gatggttcgc gccaatcaac tggaattcgc
    67681 tggcgatgaa atggaagagg ggatgaacta ctacgatgaa gagagcttgt cgctgtgtgg
    67741 cgttgaggat tttcttcagg tggtggcggc ttaccgtaat ttcgtgcagc agaagtaagt
    67801 aaatcaggcg gagcctccgt gctccgcctg agacgttaaa cagcgggcat attgcgcccg
    67861 taataaatct cgcgcatttc tttccacagc gcagcggtaa tttcctggcg ctcgctgtcg
    67921 gttaaatctt ccggtttggt gtggaacatg tagtgcttaa agtcgaactc tttaagcaac
    67981 atcttggtat ggaagatatt ttcctgatag acgtttacat ccaccatgtc atacagcgcc
    68041 ttcatatcgt cagacataaa gttctgaatc gaattaattt catggtcgat aaagtgcttc
    68101 ataccgttaa tgtcgcgagt aaaaccgcgc acgcgataat caatggttac gatatcggac
    68161 tcaagctggt ggatcaggta attcagcgcc ttcagcggag aaatcacgcc gcaggtagag
    68221 acttcaatat cggcgcggaa ggtacataaa ccgccttcag gatgactttc cgggtaggta
    68281 tgtacgcaaa tatgactttt atcgagatgg gcaacgaccg tttctggcag tgggccgggg
    68341 tgttctgttt tgtcgataag ttttgggtcg accggttctt cactcaccag aatagtgacg
    68401 ctggcacctt gtggctcgta atcctggcgg gcgatgttaa gaatattggc cccgataatg
    68461 gaacaggttt ctgacaggat ttcggtcaga cggttggcat tatagagttc atcgatataa
    68521 gcaatataac cgtcgcgctc ttcggtagtt ttggcgtagc agatatcgta aatacaaaaa
    68581 ctcagacttt tggtcagatt attaaagcca tgcagtttca gttttttcaa tttcttatct
    68641 tctccttagg acggctgtga agccagtgca tcttgcagat actggggtaa ggcaaaagct
    68701 gccgtatgga ctgccggatt gtaataacgg catttcaggc cagaagcgag aaaacgcgcc
    68761 tgaataattt cggttgagag atggcgtaag gcgtcgttat ctgtcgccca tgcaaaggtc
    68821 atgatgccac cgtaataggt cgggatcgcc gcctgataaa agccaacatc gctgaagtaa
    68881 tggctgagtt tgcgatgact gtcgatggcc tcttcctgct gtaaaaagca gacgccgttt
    68941 tgtgcgacga agataccgcc aggattcagg caacgtttgc aaccttcata aaatgctgag
    69001 gtgaacagac tttcgccggg accgatagga tcggtgcagt cggagataat gacatcaaaa
    69061 gtctggctgg tttgattaac gaaattgacg ccatcgtcga tcaccagttt aaagcgcgga
    69121 tcgtcgtaac taccggcgtt atggttgggt agatactgac ggcagaacga cacgacaccc
    69181 gcatcgattt ccaccatcgt gattgactca acatttttgt gtcgggtcac ttcacgcagc
    69241 attgcgccgt cgccgccgcc gataatcagc acatgtttcg cgtgaccgtg ggccagtagc
    69301 ggaacatggg tcatcatctc atggtagata aactcgtcac gctcggtggt ttgtactaca
    69361 ccatccagcg ccattacgcg accaaatgcg gcgttctcaa aaatgatcag atcctggtga
    69421 tcggtctttt catgatacaa aacgttatct accgcaaagt actgcccaaa ctggtcgtgt
    69481 agcgtttcat gccactgttt tttttcggcc atgggttgat acctcctttg ttaacacccg
    69541 taaaaaaagg gcgcaacata atagctaaca ttgaccgcgg atgcacggtc aatatttcta
    69601 caaaaaggta tcagggatta tttgacgtag gcaagcaggc ttaaggaatc gcgggccagg
    69661 gctttgcact ttttagcgac gggaatgcca atgccgctga gatcgcggta gctgtcttca
    69721 ccgagggctt tcatgtcgaa ggtgtcgtaa ttactgagat cccactggtt ttgctgggcg
    69781 aaaaagacca gtgcgcgacg aatttgcccg ttaggtaagt tctggtaacc acaatcgttc
    69841 ttcagaaaga caaaaactgc cgttaaatcg gccatatctt cggcttcaga ctcgctgagc
    69901 gcgtaactgt ttgcgcagac ggccatcagg ctgccgaata acactgttct gaaaaacgtc
    69961 ttcattgctt ctaccagggg cttaaagaag ataaacgtta gcacactgcg agcgaggcga
    70021 cgaccattat tgtcgattaa attgtgtctg cgacttgacc ttcccgtaag gggaaggact
    70081 atgctcaacg tttgattttg tttcgcctgc ttaagaataa ggaaataact atgcaacgtc
    70141 gtgatttctt aaaatattcc gtcgcgctgg gtgtggcttc ggctttgccg ctgtggagcc
    70201 gcgcagtatt tgcggcagaa cgcccaacgt taccgatccc tgatttgctc acgaccgatg
    70261 cccgtaatcg cattcagtta actattggcg caggtcagtc cacctttggc gggaaaaccg
    70321 caactacctg gggctataac ggcaatctgc tggggccggc ggtgaaatta cagcgcggca
    70381 aagcggtaac ggttgatatc tacaaccaac tgacggaaga gacgacgctg cactggcacg
    70441 ggctggaagt accgggtgaa gtcgacggcg gcccgcaggg aattattccg ccaggtggca
    70501 agcgctcggt gacgttgaac gttgatcaac ctgccgctac ctgctggttc catccacatc
    70561 agcacggcaa gaccggacgt caggtggcga tggggctggc tggtctggtg gtgattgaag
    70621 atgacgagat cctgaaatta atgctgccaa aacagtgggg tattgatgat gtcccggtga
    70681 tcgttcagga taagaaattt agcgccgacg ggcagattga ttatcaactg gatgtgatga
    70741 ccgccgccgt gggttggttt ggtgatacgt tgctgaccaa cggtgtaatc tacccgcaac
    70801 acgctgcccc gcgtggctgg ctgcgcctgc gtttgctcaa tggctgtaat gcccgctcgc
    70861 tcaatttcgc caccagcgac aatcgcccgc tttatgtgat tgccagcgac ggcggtctgc
    70921 tacctgaacc ggtgaaggtg aacgagctgc cagtgctgat gggcgagcgt tttgaagtgc
    70981 tggtggaggt taacgacaac aaaccctttg acctggtgac gctgccggtc agtcagatgg
    71041 ggatggcgat tgcgccgttt gacaagccgc atccggtaat gcggattcag ccgattgcca
    71101 ttagtgcctc tggtactttg ccagacacat taagtagcct gcctgcgtta ccttcgctgg
    71161 aagggctgac ggtacgcaag ctgcaactct ctatggaccc gatgctcgat atgatgggta
    71221 tgcagatgct gatggagaaa tatggcgatc aggcgatggc cgggatggat cacagccaga
    71281 tgatgggcca tatggggcac ggcaatatga atcatatgaa ccacggcggg aagttcgatt
    71341 tccaccatgc caataaaatc aacggtcagg cgtttgatat gaacaagccg atgtttgcgg
    71401 cggcgaaagg gcagtacgaa cgttgggtta tctctggcgt gggcgacatg atgctgcatc
    71461 cgttccatat ccacggtacg cagttccgta tcttgtcaga aaatggcaaa ccgccagcga
    71521 cgcatcgcgc aggctggaaa gataccgtta aggtagaagg taatgtcagc gaagtgctgg
    71581 tgaagtttaa tcacgatgca ccgaaagaac atgcttatat ggcgcactgc catttgctgg
    71641 agcatgaaga tacggggatg atgttagggt ttacggtata aaaagaccgt attcagaaat
    71701 atgcccggat ctctccgggc attatggtta cttcacatca tccggcagcg cataagccac
    71761 aatatagtcg cccatcttcg taccaaatga accgtgaccg cctgcggaga tcaccacata
    71821 ctgcttgcca ttcacttcat aggtcattgg cgtagcctga ccacccgctg gtaaacggcc
    71881 ctgccacagt ttttcaccgt tgctcatgtt gtaagcgcgc aggtagttat ctgccgtagc
    71941 ggcgataaac agtacgttac ccgctgtgga gattggcccg cccagcatcg gcatacccat
    72001 attgaacggc accggtacag gcatcgggaa tggcatactg tcctgcggcg taccaatacg
    72061 tttcttccac accacttcat tggttttcag atccaatgcc gagatatagc cccatgctgg
    72121 ctgtttacat ggcaggccaa acggtgagag gaacgggttg agcgtgacac catacggtac
    72181 accgtactgt ggctgaatgc cggattccgt acccgtgcct ttggcatctt tcggctgttc
    72241 catcgggtta ccaggaccgc gtgggatcag tttcgaaaca aacggcagtg ccattgggtt
    72301 ggcaattgcc acttcacgat tcggatcaac ggaaatcccg ccccattcga acatccccag
    72361 gttacccggg aagaccagcg taccctgttc agatggcggg gtgaaaatgc cttcatagcg
    72421 catctggtgg aacatcacgc ggcacaccag ctggtcaaac atggtggctc cccacatatc
    72481 cgcaccgctc aaatctttcg tcggacggaa gctcagttca gaaaacggtt gagttggggt
    72541 tacgtaatcg cctttggcag caccttgggg aaccggtttt tccggtgcag gaaccaccag
    72601 ttcgccatta cgacgatcga gcacaaaaat gttgccggtt ttcgccggag cataaatgac
    72661 tggcactttc tgaccattaa cggtgatgtc cgccagcgtc ggctgtgccg gaagatccat
    72721 atcccacagg tcgtggtgaa cggtctggta gctccacgcc agtttcccgg tagtggcatt
    72781 cagcgccaga atcgagctgg cataacgttc ctgttccggt gtgcggttac cgccccagat
    72841 atccggcgtg gtcacgccca tcggcagata gaccagattc agcttcgcgt cataggccgc
    72901 tggtgcccac gagtttggcg agttaaaggt aaatgtgtgt tcgtcagacg ggatcgcgtt
    72961 cggatctttc gcgcccggat caaaagccca cagcagctcc ccggtgttga catcaaaacc
    73021 acggatcacg ccagacgttt cgcgggttga gaagttatcg gtgactgaac cggccatcac
    73081 gatggtttta tcggtgataa ttggcggcga agtcggctca tacagacccg gtttggtgtc
    73141 cggcatattg ctttgcagat tgagcacgcc tttattggcg aaggtttcgc acagcttgcc
    73201 gttttcagcg ttaattgcaa tcaggcgacc atcattgacc ggaagaatga tacgacgcgg
    73261 gcaatccgcc atcacttctg gcgaggcagt ttctgctttg gcttcatgat aagagacacc
    73321 acggcaggtt acatgctgga aggactcgtt ggttttcagc tcaggatcgt aatgccattt
    73381 ctctttgccg ctggcggcat cgagcgcaaa caggcgctgg tgagcggtac ataagtaaag
    73441 ggtgtcaccc actttaatcg gcgtcacttc attggtgatt tcgcccggat cgttcggctg
    73501 cttcacatcg ccagtccgga acacccaggc ttctttaagg ttgtggacgt tatcagcgtt
    73561 aatttgtttc agaggtgaaa agcgttgacc ttcctgattg cgaccatacg caggccagtc
    73621 ctgatcggca accggtgaga tagcttcggc aggtgtggca tcggcgctta aggtgccgtt
    73681 gatttcctgc ggatcgttaa atcccgccca ggtgaggatt ccgccactaa tcagcaatgc
    73741 caccaccagt gcggcaactg cgccgctagc aggaatgacc aggcgacgcc agacaaacgg
    73801 caggatcagc cagatgccga agaagaccag aatgtcgctg cgcggagtca gcgcccagaa
    73861 gtcgaaacca acttcccaga cgccccaaat catggtgccg agcagcaggg cggcgtacag
    73921 ccaaagcgcg gcgcgtttac tgcgccacag catccaggcg acgccgagca tcacaaggcc
    73981 agcgataggg tagtaccagg agccgccaat cgcgaccagc cagcctccgc caatgagtag
    74041 atacagcccg caaagtgctg caaaaagggc tgttagcgtg acgagtaatc gtcgcgagcc
    74101 tgtattgtta attgccataa agagacacca tttcaattca ttaatgtttt agtagcaatt
    74161 aattataggt tttaacatgt gtgatcgtca tcacaatttg agctttatta acagattccg
    74221 cgaatgaata gttttactgg tatactgcgt gtcttgcgct ttgttgcggt gccaaaacct
    74281 gcccgtgcga agtgatttgt ttttaaatca tatggttaga gatatgaaac atactgtaga
    74341 agtaatgatc cccgaagcgg agattaaagc gcgtatcgcc gaactgggtc gtcagattac
    74401 tgagcgttac aaagacagcg gcagcgatat ggtgctggtg ggtctgctgc gtggctcatt
    74461 tatgtttatg gcggacctgt gccgtgaagt tcaggtatct catgaagtcg actttatgac
    74521 cgcctccagc tacggtagcg gcatgtccac cacccgtgat gtgaaaatcc tcaaagatct
    74581 ggatgaagat atccgtggca aggacgtgct gattgttgaa gatatcatcg actcggggaa
    74641 tacactgtcg aaagtgcgtg agatcttaag cctgcgcgaa ccgaagtcgt tggcgatttg
    74701 tacgctgctg gataaaccgt cccgtcgtga agtgaacgtc ccggtagaat ttatcggttt
    74761 ctcgatcccg gatgagtttg tggtgggtta cggcattgat tacgcacagc gttaccgtca
    74821 tctgccgtat atcggcaaag tgattctgct ggacgagtaa gtgtgaagtt gccggatgtg
    74881 ttgcatccgg catggcattt ttatttgtgg ttggcgtgtt tcagcttgag gttggagatc
    74941 ccgtgacggt aacgttgttc aagggtttcg cggttagtcg ctgtgacatc cagatcacgc
    75001 agcaagccgt cgtgaatgcc gtaggcccag ccgtgtatgg tgactttctg cccgcgtttc
    75061 cacgctgatt gcataatagt ggagtggccc aggttataca cctgttccat gacgttcagt
    75121 tcacacaagg tatccagacg gcgctcttgc ggcatttcgc cgagcaatga gctatgtttg
    75181 aaccagatat cgcggatgtg cagcagccag ttgttgataa gccccagttc cgggttttca
    75241 acggcggctt gtacgccgcc gcaaccgtag tggccacaga taataatgtg ttcaacttcg
    75301 agtacatcca ctgcatactg aaccacggaa aggcagttca ggtcggtgtg aatgaccagg
    75361 ttagcaacat tacggtgaac aaagagttcg cccggctcaa gaccggttaa acgttctgca
    75421 ggaacgcgac tgtcggaaca tccaatccat agaaagcgcg gtttttgcgc ttgcgccagt
    75481 ttctcaaaaa acccgggatc ctcttccacc agcatttttg accatagtgc attgttgctg
    75541 atgagtgtat ctatgtcttt catggaggtt aacgacctgt aaccaaataa ttacgtttgg
    75601 ctaatatagg gcaactccgg gacgatttaa accacagata aagtgtaaga acgtaaggta
    75661 agtaaaaatt tatgaccatt gcactggaac ttcaacagct taaaaaaacc tatccaggcg
    75721 gcgttcaggc gcttcgtgga atagatttgc aggtcgaggc gggtgatttt tatgcgcttc
    75781 tcgggccgaa cggggccggg aaatcgacca ctatcggtat tatcagctct ctggtaaata
    75841 aaacctccgg gcgggtcagc gtatttggtt acgatctcga gaaggatgtc gtgaacgcta
    75901 aacgtcagtt gggactggtg ccgcaggaat ttaacttcaa cccgtttgaa accgtgcagc
    75961 aaattgtggt gaaccaggct gggtactacg gtgtggagcg taaagaagcg tacatccgca
    76021 gcgaaaagta tcttaaacag ctcgatttat ggggaaaacg taacgaacgt gcgcgtatgc
    76081 tatctggcgg gatgaaacgc cgtttaatga ttgcccgtgc gttaatgcat gaacctaaac
    76141 tactgattct cgacgagcca acggcaggcg tggatattga acttcgccgc tcaatgtggg
    76201 gctttttgaa ggatttaaac gacaaaggca ccactatcat tctcaccaca cattacctgg
    76261 aagaagcaga aatgctgtgc cgcaatatcg gcattattca acacggtgag ctggtggaaa
    76321 atacctcgat gaaggcgctg ctggcgaagc tgaaatcgga aacttttatt ctcgatctcg
    76381 cgccgaaaag cccattaccg aagctcgatg gctatcagta tcgactggtc gataccgcta
    76441 cgctggaagt tgaagtgctg cgtgagcagg ggataaacag cgtattcacg cagttaagtg
    76501 agcagggcat tcaggtatta agtatgcgta acaaagctaa ccgtctggaa gagctgtttg
    76561 tttcactggt taatgaaaaa caaggagatc gcgcatgatg catctttact gggtggcgct
    76621 aaaaagcatc tgggcgaaag agatccatcg ctttatgcgt atctgggtgc agacgctggt
    76681 gccgccagtc atcaccatga ccctttactt tattatcttc ggtaacctga ttggttcgcg
    76741 tattggcgat atgcatggct tcagctacat gcagttcatc gtaccggggc tgatcatgat
    76801 gtcggtgatc accaacgcct acgccaacgt cgcgtcatca ttttttggtg ccaagttcca
    76861 gcgtaatatt gaagagctgc tggtagcgcc ggttccgact catgtcatta ttgccggata
    76921 tgtcggtggt ggcgtggcgc gtggtttgtt tgttggtatt ttggtgacgg caatttcact
    76981 gttttttgtg ccgtttcagg tgcattcgtg ggtattcgtt gccttaaccc tggtgctcac
    77041 tgcggtgcta ttctcccttg cgggtttgct gaacggcgtg tttgccaaaa cgttcgatga
    77101 catcagcctg gtgccaacct ttgtgttaac gccactcacg tatttgggcg gggtctttta
    77161 ctccctgact ttgctgccgc cgttctggca gggactgtcg cacctgaacc cgatcgttta
    77221 tatgatcagt ggtttccgct acggcttcct cggtatcaat gatgtgccgc tggttactac
    77281 ctttggcgta ctggtggtct ttattgtggc gttttatttg atttgctggt cgctgatcca
    77341 acgtgggcgt ggtctgcgta gctaaggcta tttcctctcc tctggattcg ggggagagga
    77401 gttttgacga ctatcaccct ttatcaacca tggtcagggt agactgattt tcggctaagg
    77461 aggaaggcga tgctaggttg ggttattacc tgtcacgatg atcgggcgca agagatactg
    77521 gatgcgctgg agaaaaaaca cggggcgctt cttcagtgcc gggccgtgaa tttctggcgc
    77581 ggattaagct ctaatatgct cagccgcatg atgtgcgatg ctctgcatga agcggactct
    77641 ggtgaaggcg ttatcttctt aaccgatata gccggagcgc caccgtaccg cgtggcttca
    77701 ttattaagcc acaaacactc ccgttgcgaa gtgatttctg gtgtcacgtt accgttaatt
    77761 gagcagatgc tggcctaccg tgaaacgtta tccagcgcag agtttcgcga gcgtattgtc
    77821 gaactgggtg caccggaggt gagtagtctt tggcaccaac aacaaaaaaa tccgcctttc
    77881 gtcctcaaac ataatttgta tgagtattaa cccgcgattc tgatggcgct tttgctacaa
    77941 taaaagcgtt gtttcaccct cggttatttt ttaatgtaca aacaagctgt tattctcctg
    78001 ctgatgctgt ttaccgcaag cgtcagtgcc gcattacctg cccgttatat gcaaaccatc
    78061 gaaaatgccg cggtctgggc gcaaattggc gacaaaatgg tgacggtagg gaatattcgg
    78121 gccgggcaaa tcattgccgt ggagcccact gccgcaagtt attacgcatt taattttggc
    78181 tttggtaaag ggtttatcga taaaggccat ctcgagccgg ttcaggggcg acaaaaagtt
    78241 gaagatggtt tgggtgacct caacaagccg ctgagtaatc agaacttaat aacctggaaa
    78301 gatacgccgg tttataacgc accgagtgtg ggcagtgcgc catttggagt actggcggac
    78361 aatttgcgct acccgatttt gcataaactg aaagacaggt taaatcaaac ctggtatcag
    78421 atccgtattg gcgatcgact ggcctatatc agcgcgctgg atgcccaacc cgataatggc
    78481 ctgccggtgc taacctatca ccatattttg cgcgacgaag aaaacacccg ttttcgccat
    78541 acttcgacga ccacctcggt acgcgctttc aataaccaga tggcctggct gcgcgacagg
    78601 ggatacgcga cactgagcat ggcgcagttg gaaggttacg tgaagaataa gatcaatctc
    78661 cctgcgcgag cggtggtaat tacctttgat gatggcctca agtcggtgag ccgctatgcg
    78721 tatcctgtgt tgaaacaata tggtatgaag gcgacggcgt ttattgttac ctcgcgcatc
    78781 aaacgtcacc cgcagaaatg gaacccaaaa tcgctgcaat ttatgagcgt ttctgaactt
    78841 aacgaaattc gcgatgtatt tgatttccag tcacatactc attttttgca tcggatagat
    78901 ggttatcggc ggcctatatt gctgagccgt agtgagcaca atattctgtt tgattttgca
    78961 cgttcacgcc gcgctctggc gcaatttaat ccacatgttt tgtatctttc ttatccattt
    79021 ggcggattta atgacaaagc cgtgaaggca gcaaaagaag ccggatttca cctggcggtg
    79081 acgaccatga aaggcaaagt aaaaccgggg gataatccgt tgttactaaa acgactttat
    79141 atcttaagaa cggattcgct ggagacgatg tcgcggctgg tgagtaacca gccgcaggga
    79201 taacaatcag gcaacctgta ccggaatcgc tttcgcggta cgtttcattt cgttgtcgcc
    79261 ttcaaaatag gcgacgttgg gtcgccaggt gcgagcttct tcatctggca tggtaacgaa
    79321 gctggcgatg atgacaatat cgccgacgct ggcgcagtgg gccgccgcac cgttaacgga
    79381 aataattctc gaaccgcgtt ctgccgcgat ggcataggtg gagaaacgct tgccgttggt
    79441 cacattccag atatcaatgg cttcgttttc gagaatacca gctgcgtcaa gaaaatcctg
    79501 gtcaatggcg caagaacctt catagtgcag gtccgcatga gtcactttca cgcggtggag
    79561 tttgccctgc agcatcgtgc gaatcataac ttctaccttt ctaccctgtc gttaacgaag
    79621 caggcgatgc ctgctttgag gaaattctca cgcagtattg cccgattttt gtttagtgtc
    79681 tactcatctg acggcatttg catcagcagt ttgcgtaccg tgccgaagcg tgccatgtaa
    79741 cgcctgtaac caattgaaat ttctctgaac gctgctcggt aaacactaaa gaggcggctg
    79801 acgacggcgc gccttgactg gatactgcct tcacgcaaga cagcacggaa ggcagggaag
    79861 atggatgcac cgagtaccac accgcatgat gcggtgttta aacaattttt aatgcacgcg
    79921 gaaacggctc gcgactttct ggatatccat ttgccagcgg agctacgcga actgtgtgac
    79981 ctcgacacgc tgcatcttga gtcggggagt tttattgaag aaagcctgaa agggcacagc
    80041 actgacgtgc tctattccgt gcaaatgcag ggtaatacgg gctatctaca tgttgtaatt
    80101 gaacaccaaa gcaagccgga caaaaaaatg gcctttcgca tgatgcgtta ttctattgct
    80161 gccatgcacc ggcatctgga ggcagatcac gataagctgc cgctggtggt gccgattttg
    80221 ttttatcagg gcgaggccac gccttatcca ctctcaatgt gctggtttga tatgttttac
    80281 tcgccggagc tggcgcgacg cgtctataac agtcctttcc cgctggtgga tatcactatc
    80341 acaccggatg acgaaatcat gcaacatcgg cggattgcga ttctcgaact gctgcaaaaa
    80401 catattcgcc agcgcgactt aatgttattg ctggagcaac tggtcacgct gattgacgaa
    80461 gggtacacta gcggaagtca gttagttgcc atgcaaaact atatgctgca acgcggtcat
    80521 actgaacaag cggatttgtt ttatggtgtg ctgagagaca gggaaacggg aggggagtct
    80581 atgatgacgc tggcgcagtg gtttgaagag aggggaagac aggaggaaag gcaggaggta
    80641 agacaggagg taagacagga ggtaatacaa gaggttagac aggaagtaag acaggaattc
    80701 gccctgcgtt ttctgagtaa agggatgtct cgggaagacg ttgcagagat ggcaaattta
    80761 cctcttgctg aggttgataa gctgattagc taagttatct gcattatcag ttatagccag
    80821 ataattgtta ttgttaactg accagataat taagggaaca tatggaaata aagacacgga
    80881 gagaaaccag gcagacgttg gcgcagtggt ttgaagagaa ggaatttcag aagggatata
    80941 aagagggact ccagaaggta agactggccc agcgtcttct gagtaaagga atgtctcggg
    81001 aagacgttgc agaggtgaca gctttatctc ttgcagagat tgataagcta attaactcta
    81061 actaagttgt ctacgatatg aataattgct tacagatgac gtggcaatga ataactggcg
    81121 ccatcagccg tagcgccagt taaatattac gccagttcga cgattttgtt gtcgatcagg
    81181 cgagcatcgc caagccaggc ggctaccaga atcaccgctc gtttgctgtt ttcagagatt
    81241 tccagcaagg tgtcggcatc gcgaatctga atatcatcgg cgcggaagcc tttttcattc
    81301 agttcttgcc cggcaatagt aataatttca tcgagatccc gttcgccagc ctgcaatttg
    81361 tcggcaatcg aacttaaaac cttgtacagg ccgggcgcaa ttttgcgttg ttccgccgtc
    81421 agataaccgt tacgggaact cagcgccaga ccgtctttgg cgcgcataat cggtacgccg
    81481 ataatctcaa tatcaaagcc catatcggca accattttgc ggatcagcgc cagttgctga
    81541 aaatcttttt caccgaagca ggcgatgtcc ggctggacca ggttgaacag cttgctgaca
    81601 atcgtcgaaa cgccgcgaaa atgtcccgga cggctggcac cttccagcat ggtggaaaga
    81661 ccgggaacat caacataggt gtgggtttct gtaccgttcg ggtagatctc ttttaccgaa
    81721 ggcgcaaaaa ctaaatccac tttacgtttg ttcagctttt cgcagtcctc ttgcaaggtc
    81781 cgtggataac gtgccagatc ttccgggcgg tcaaactgca ttgggttaac gaaaatactg
    81841 acgacgacca catcggcgcg ggctttggct tcgtcgacca gcttcatatg gccatcgtgc
    81901 aggttaccca tggtgggcac cagcgccacg cgcttacctt ccatacgcag gcggcgaatt
    81961 tgctgacgca gcagcggcag ggtttcgata attaacacaa cgtcactcct taatggaaac
    82021 tgtgttcttc gcccggataa acgccggact ccacttcagc catatactgc cgcacagccg
    82081 cgcggatgtc gcccgtttcg gcgaggaaat ttttggcgaa tttaggaata tgaccgccgg
    82141 taatgccgaa cgcgtcgtgc atcacgagga tctgcccgtc agtgacgttg cccgcgccaa
    82201 taccgataac cgggatcgcc agtgcttcgg taatgcgttt tgccagctca accggcacgc
    82261 actccagtac cagcagttgt gccccagcag cttctaatgc caatgcatcg ctgagcagtt
    82321 gatcgcccgc ttcatcgccg cgcccctgga ctttgtagcc accgaaaata tttactgact
    82381 gtggggttag gcctaaatga ccacaaactg gaacggcacg ttcggtcagc atttgtacgg
    82441 tttccaccag ccactcaccg ccttcaattt tgaccatgtt ggctccggca cgcattaccg
    82501 ttgcggcgtt ttcaaaggct tgttccggcg tggcatatgc cataaatggc aggtcagcca
    82561 gcagaaggca gtttggcgcg ccgcgacgca cagcggcggt gtgataggcg atatcggcaa
    82621 cggtaaccgg tagcgtggag tcatgcccct gaacagtcat gcccagtgaa tcgcctacca
    82681 gcatgacgtt aagtccttct tcggcaaaca gttttgcgaa gctatagtcg taagcggtga
    82741 tggttgcgaa acgttttttg tcctgcttgc atttctgcaa tgaagcaatc gtggttggtt
    82801 tcatagcgta tcctgataaa tgatgttgtg ctgtctcgca ttttatcagt cacattggtg
    82861 ggggcaatga tttatccgta tcgcaccgcc gttgtctggc ggtgcgatag tgttatcagg
    82921 ggtaggtaac ctgaaaagtg ctggtggctt taaaatcccc cggttctata gcaatattac
    82981 cgtcttgttt taatgtagcc tggaaatgaa gtggatacgt tataccgtca tcttccgggt
    83041 aaatcgcatc tgaatcgtta ttctgcgtct ggcccgtatt atctttataa acagaagttg
    83101 aatcattagg tttcagtatc attagggcac ttttactgtt tgctaatcct tcaatcaata
    83161 ccccaacgcc ttttgctgca ccacttcctg tgagagtgtt accaaggagt tgcctgtttt
    83221 cagtaccaac ctttgttgaa actaattttg tctcgatatt agtcacacga acgcagtttt
    83281 gaagtgaaat atcaaaagga accggtgtgg caccgtttct tatttgtgct tcactatact
    83341 cgcccatttt taccgtagaa ccagtaacag atgttccact taatatagct gtaaaacaag
    83401 tgggattact taatttaata tttagtaggt caaaatcaac tctaagaaaa tagctgtgtt
    83461 cgttaatgcc gataccagca ccataagctt taaatgaata taaatagttt gatgagcgcg
    83521 ataatgaaac ttgttgagtt actgttggat caaagttggt atctgtataa aattcgatgg
    83581 taagattttg ataaataccg cctacagccc aatatttgct ggatgtgttg gcattgttac
    83641 aactttggta taatatgctt tcgcttgggt tgtaccatga aaaatattgt tctgcagaat
    83701 caccaatata tattcctggt gaactaacgt tagttacggt gccgtaagct gaccacatat
    83761 ttgaaattaa tattgtataa tacaaaccgg gaacagatgt attgaatagt ttatggttac
    83821 catatctttt tccagagtca accattgcat tttcgatacg cattgccccg ccactggtgt
    83881 tattgcttct gttacaataa agaaagcctc cgccagaagc agtatctaac tgactccaat
    83941 gtaatttcac ccctgttgga cccagttgtg ttggtttata aaatactaaa ttatttgtac
    84001 tggtaccata cctgaacacg actgtcacat ctccatttgg cccggtttct ctccattttt
    84061 gatctgacgg accaacgccg tagttattcc caacaacata tcctacgaaa tcatcagtgc
    84121 cagcactcgc ggtataacaa ctcaagcaca gaattaaaaa aagaaaatat ctgaagaatg
    84181 tcttcatttt cactccacca tccactgctg tagtagtcgc agtaatttgt ttttggtatg
    84241 ttactcgtag taaatatcaa ttaatacatg gcttatgatt tggccgggca tgacatttaa
    84301 tacagggttg attttttgca tccgtgtata gaatttccag gatgaattgt ttaaatcagc
    84361 agtcatcacc ggataaattg aacgagaact gcccgctggg gtaagaacat taaatatatt
    84421 agccgggtcc tgagtggaaa atattactac acctacgttt tgagcgccgg cgacattttc
    84481 atttgcaaaa atttgctgag agcctgtcgc catcacgcca ttaagcggtt taaagttaat
    84541 atgtaactga tttaacacat ttccagaacc ctggatggcg cagtcagtca cagtgatagt
    84601 gaactctctc ccacccggat aatcatcttc aggtgcgacg ttaccagaaa aataatccac
    84661 accaaccaca ccaagatcga tattaccaag gttactgagg ccacttttac atgtactgtt
    84721 cttgatattg gcaaccatat ccacatccag ccctgcatat acaggactgg atgtggcaaa
    84781 caataatgcc aggaacagac ttgtttttat cttaattttt agttgagagg aaagcataat
    84841 cggtccctga ctttaatggc ctgttagtta taggtgatag aaaatgttgc aggtgcggaa
    84901 aacggaccgg cagtgatgtc ggttttgctt ttatttttct ctaccaccag gcgtgcactc
    84961 ataggatgat atactgacgt agttcctgtt gcagtggaga tattcacttc ctgagcgact
    85021 ggtgttacgc agctaaattg agtcttgccg tctgtaccag gtgtcgtggt attccatact
    85081 tcaaccgcaa cagcatttgc tttatcagca gcggcggagc cgtttgcaaa accaggccca
    85141 tcgttggctg ctccttcaca agttgcgcgt ttagttaatt ttacgagtgc ttttttatta
    85201 ggaataccag cacaatcctt aaactgtaac ttaaatattt taatttttgt tttggcatca
    85261 atttcaggaa tgtaagcatc cccaaatgca ataacagaaa taggctgatc attgtcatcc
    85321 accaggctgg cggtacaggt tcccgtctct acggttgctt taacattcag cttaacgcta
    85381 tcggtagctg caaacaattg gctggtgaat agggatgccg caaaaaaaac accagcgggt
    85441 agtccataac ataatgtttt agatttcatt attatcatcc ctgttattca taaatgaagt
    85501 tgaaagttgc ctgggcgcgg aaatcgccag gaacaccact gccagccgtg gtttcgcgca
    85561 gtgcaacggt cagttcaaga gttttgtctg tatcactaat ttcccatgga ataaaactcg
    85621 gcgcactgtt tgggattaag aatgtcgaat catcttcacc aagtgctttt atacccatac
    85681 caatataatt agttgttgat gtagtgtcag aagagagtgg aacaattaat gcgggagtag
    85741 ttccggaagc attcccactg agcctggtat tgattttgct gacgcctgtg gtacaaccgc
    85801 tggcaaccag attaaaattc gcctgtgctt gagtcgtttt atttgcaatt ttgtccagac
    85861 caatagttcc tgggaaagtt aatgtgtagg tgtcactccc atcaggggtg acattgtcgc
    85921 ctgataacgt aatgttacaa gttgatgctt ttacggttgc tgtaaaatca acattaatgt
    85981 ctgttgcaag tacagaggat gataaaaata atccagtcag tattgccaat ttatgcagtg
    86041 ttattctcat tatgtgaaat tccctgttgt tactgaatct gacaactaat tccattcaga
    86101 ataatagttt gcgctatttt ttctggtgct gcgctctgct ggtaatgagc aaggcaagtg
    86161 acaggtttac cgtcgtcaag ccagttgata cgtatgttac cttgttgttc tatacctcga
    86221 acaaaggcct gaccaccttg ccctacattg ccaataatat ttccgttctc gtcataaata
    86281 tctgcggcaa acggaatgtt tttaccgtca gttcgcttga tgttcataat cgctgattgt
    86341 ccctgaactg tttcaaaacc agcaaagaca acagaccctt ggcgggggac agtaatagca
    86401 ctggtacttt tcaattcaac gtcattttcc agaccgttaa tatcgagtgc aattcggttt
    86461 tcatgataag gggagagcgc gttagtaaca ccatatcccc aacgatctat cgtactatta
    86521 ccatagttaa tacgcgcccc tttagctcct ggcgcttgta caacggccag agtgtctgag
    86581 tcgctaaagc tgtcattact gaaggtcagg ccgccgctat gtaaaacaaa tccgccgtcg
    86641 gtattaaatg agatttgacg gctattatca ctgcttgcgg aaactgaact ggaaagagtt
    86701 ccccagggag attcatagct tgcatatccg ccgatatagc ccaaatcatc actggatttc
    86761 atcatcgaat agcctgtatt gacgctataa ctgatatggt tttcggtgct ataaccacta
    86821 ctgctgatac tgagttgatt gctgccgttg aaatcactat ttaactgagt atcaatgctc
    86881 tgaaaaccag agtcgcgatg ttctgaaccc agtaactttt cgataggaat gctaaagctt
    86941 agatagatgc tgtcttcatt accgccgtcc tggctccagg accgttgggc actaatgctg
    87001 tagcttcccc acgatgcgct gttactataa ccaatggagt agttagtatt attttgtccg
    87061 tccgcccaat agtcagacca acttccggca agatagaatg agccatagtc tttcttttca
    87121 aacttgaggg gttgattaat actgaccgta acctgatttt tcatgcgtga atagttacgc
    87181 atatttttag gttccaggtc ctgttccgga tgttttactt catcgatcaa tgtcagtgca
    87241 tcgttaagcc ccagataatt ctgggttgaa taacggtaag cggcgatatt gagcgaggtt
    87301 ctggtatctt caaataactt attccaggag atgcgatagc tttgcccgcg gtaggtttta
    87361 tcgtccggaa tttgcacatc cgagtgggtt acatcgactg aaaacgcacc gtacgcggta
    87421 ttcaggccaa ggcccaacag cccggcagta tagttattat cggtaatttg aataccggta
    87481 taacctgtaa gatagttgtt cagaccatag tagtagctgg cctggaacaa atttggctca
    87541 ttttgaatat cgtcttttaa tacctgacca gcactgatat cccatcttcc aacaccaggg
    87601 cgttgcatct gaattaccga agaaaatggc tgggaaaaag ttcgttttat gccatcagat
    87661 tcttcgattg tgataatgag atcgctgccg tagcctgatg ggcttaaatc atcaataaca
    87721 aatgctcccg gcggtacagt agtttcatat attttatacc cgccctgggt aatggtgact
    87781 tttgcgttgg tgttagcgac accatgaata ataggcgcaa aactagctaa cgcaggcggt
    87841 agcattcggc tgtcgctgta taaacgaata ccgcgaatac tgacagcatc aaaggtttcc
    87901 ccagttgtgt atgactcacc cactattaac tgtgaacgca aagaggccag gtcgcgctgc
    87961 aaatagcgat tctgaaaatc gtaatcactg cctacattgg tcatccagtt gtagttgccg
    88021 gttgcgcgaa gccgccatgc ccccagattt ataccgccgt taaatgccgc ataaacactg
    88081 tcgttttttc tgtctggaat ttcgctgtga tatgcgttca cattgtaggc cagcattgcg
    88141 gcgttaatac cgttttccca caatgacgga tcaacatagt tttggtaatt cttcattatc
    88201 caggcttgag gaacgttgat atccagccgt tgatcgttga cgtcataatg aactgaagcc
    88261 tggggaatga tattcgccaa atctagacaa tctccgagtt cgccttcgcg ctgtagaagg
    88321 atggaattct cggcatttat atctggttta ttaatgtgaa actgcaataa attcttcagg
    88381 gtgatacaag cctgcgcatt cttcttacct tcgagggtaa taaaggaaat gctttggttg
    88441 ataaccggtt gatcattgat ataaacactg acgtcataca cgccgggcaa ggtagggtta
    88501 ccttcggtat accgactaag gtcgatgtta gaagcatctt gccccatcaa aaaggtatta
    88561 tcatattcaa cgtgttcagc gcttatggca caggggctta atagcaatgc gcaaaacgag
    88621 gctatatatg taagtttgtt attatgcgtt tttatgattt ttctggacac gttgtgcttc
    88681 ctgctgcgtt tattcctgat ttagttacag gctggcattg ccttcaattg caccaccaaa
    88741 gtcatttatg gcgaagaaat gcactttggc agaacttgct ttaccactca tgccttttat
    88801 gtagaaggtt tcttcactca gcggggctac catttttaca tccagggggt aggttttgcc
    88861 attggcgact aaatcaccac tactgaatga gacgtgatac ggtgtcggat ttgcgacgcg
    88921 caatgcagtt tttccagcag aggttgccca tgaccatttc agtgctgcgg gtgcatctga
    88981 tggcagtccg tttaaacctt ccgggcgata aaataatttg atacgcgtac ggaatgccaa
    89041 ttgcagaaga ctctggttgg cgactttatc tgcgtcaggt ttgggtggaa cctcgagtac
    89101 gttaaaccag aaaacacttt ctcggtcttt tggcagcggt gaggaagccg tgtacatcaa
    89161 tttaatagtt tgaccacgtt tggcatcaat tcgcgaaaca ggaggggtgg cggtaaatgg
    89221 gacagtaata ctccctggtt cagcactatc gtcgccagta tccagccagc tctgaacgag
    89281 taacggatta ttccccttat tttccagccg aacattaacg cttttttcat tacttttata
    89341 aattacgcga gttcctgaaa ttacgatatc tgctattgcc gatgcgctta agctcataca
    89401 agtggcgaag catacagctg cagtatgttt agcgtttaaa aacataaacc attcccgaca
    89461 gagttaatta aaatagggag taacattcca ctattaagaa agttactccc atagatattc
    89521 agtttatgaa tctaacgaag gattactggt aagtaatggt atatgcagtg ttggttttaa
    89581 cataaccagc agttggtgcc tggcttgctt cagcacggac ataggatgct ttaaaatcat
    89641 aggttgcaga tttagtcgta gcgtccagcg tttttgtgta aatatcgcct gggttgttaa
    89701 tttgaacctg tttgatagtg gaaccatcaa tattgtgcag ggcaatattt acgccgtcag
    89761 aaggcgtgtt aatagacata tcgttgttca gagtcccttt gctgttgcca aagaacacgg
    89821 aaccgaaggt catttttgcg gtgctaccag gattcgggtt tgcattgctg cagtcaacgg
    89881 tgatgctgaa aggtttagct ttagcaccta cggtgtcatt cagtacgcca gcactgattt
    89941 cagcaacagt tgcagtttgc agaagcacca ggccatcttt gttgccacca tcaacacggg
    90001 tttcacaggt gttatcaact accagaccac tgatatttaa ctgaccaccg tccagaccag
    90061 cagaagcagt acctgcaacc attgccagca taagaccaga cagggcaaaa cctaattttt
    90121 tagacataaa aatccttgaa taaaattcca ttagtcagac tacatgtttg aagagtaact
    90181 attcatgaca caaataagag aaacaaatgt tagatattaa tgagcaatga tgttt
//
LOCUS       DADXDL010000009        85105 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.009, whole genome shotgun sequence.
ACCESSION   DADXDL010000009 DADXDL010000000
VERSION     DADXDL010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 85105)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 85105)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..85105
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.009"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            196..735
                     /locus_tag="IRB70_000819"
     CDS             196..735
                     /locus_tag="IRB70_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415458.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630768.1"
                     /translation="MKKNVLAAFITVICTTSSVMAADDNAITDGSVTFNGKVIAPACT
                     LVAATKDSVVTLPDVSATKLQSNGQVSGVQTDVPIALEDCDITVTKNATFTFNGTADT
                     TQITAFANQASSEAATNVALQMYMNDGTTVITPDTETGNILLQSGNQTLTFKVDYIAT
                     GKATSGNVNAVTNFHINYY"
     gene            818..1519
                     /locus_tag="IRB70_000820"
     CDS             818..1519
                     /locus_tag="IRB70_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HBC0630769.1"
                     /translation="MKTCITKGIVTVSLTAILLSCSFTWAAGKGGVGLAATRLVYSEG
                     EEQISLGVRNTSPDVPYLIQSWVMTPDNKKSADFIITPPLFVLNPANENLLRIMYIGA
                     PLAKDRETLFFTSVRAVPSTTKREEGNTLKIATQSVIKLFWRPKGLAYPLAEAPAKLR
                     CTSSADMVTVSNPTPYFITLTDLKIGGKVVKNQMISPFDKYQFPLPKGAQNSSVTYRT
                     INDYGAETPQLNCKS"
     gene            1544..4144
                     /locus_tag="IRB70_000821"
     CDS             1544..4144
                     /locus_tag="IRB70_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HBC0630770.1"
                     /translation="MPRTHRQHSLLSSGRVPSFIGGLVVFVSAAFNAQAETWFDPAFF
                     KDDPSMVADLSRFEKGQKITPGVYRVDIVLNQTIVDTRNVNFVEITPEKGIAACLTTE
                     SLDAMGVNTDAFPAFKQLDKQACAPLAEIIPDASVTFNVNKLRLEISVPQIAIKSNAR
                     GYVPPERWDEGINALLLGYSFSGANSIHSSAGSDSGDSYFLNLNSGVNLGPWRLRNNS
                     TWSRSSGQTAEWKNLSSYLQRAVIPLKGELTVGDDYTAGDFFDSVSFRGVQLASDDNM
                     LPDSLKGFAPVVRGIAKSNAQVTIKQNGYTIYQTYVSPGAFEISDLYSTSSSGDLLVE
                     IKEADGSVNSYSVPFSSVPLLQRQGRIKYAVTLAKYRTNSNDQQESKFAQATLQWGGP
                     WGTTWYGGGQYAEYYRAAMFGLGFNLGDFGAISFDATQAKSTLADQSEHKGQSYRFLY
                     AKTLNQLGTNFQLMGYRYSTSGFYTLSDTMYKHMDGYEFNDGDDEDTPMWSRYYNLFY
                     TKRGKLQVNISQQLGEYGSFYLSGSQQTYWHTDQQDRLLQFGYNTQIKDLSLGVSWNY
                     SKSRGQPDADQVFALNFSLPLNLLLPKSNDSYTRKKNYAWMTSNTSIDNEGHTTQNLG
                     LTETLLDDGNLSYSVQQGYNSEGKTANGSASMDYKGAFADARVGYNYSDNGSQQQLNY
                     ALSGSLVAHSQGITLGQSLGETNVLIAAPGAENTRVANSTGLKTDWRGYTVVPYATSY
                     RENRIALDAASLKRNVDLENAVVNVVPTKGALVLAEFNAHAGARVLMKTSKQGMPLRF
                     GAMATLDGAQTISGIIDDDGSLYMSGLPAKGTITVRWGDAPDQICHISYELTEQQINA
                     AITRMDSVCE"
     gene            4135..5205
                     /locus_tag="IRB70_000822"
     CDS             4135..5205
                     /locus_tag="IRB70_000822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630771.1"
                     /translation="MRIISGDSSVLRLRLLLTAVLMLWGFHAAAYTGQCHTTQGNPYI
                     GVNFGVKTLEEEENTAGKVKDEFYQWSESNDYYVSCDCDKDNVRSGLWAFAADSPLVY
                     LGDNWYKINDYLAAKVLLGVKGNTPSAVPFENLGTGSDTRWHICDPGGQRLGGKGASG
                     NSGSFSLKILQPFVGSVVIPPMALARLYECYNIPASDSCTTTGTPVLVYYLSGTINSL
                     GSCSVNSGETIEVDLGDVFAANFRVVGHKPLGSRTAELSIPVRCNTGNAELVNVNLSL
                     TATSDPDYPQAIKTSRPGVGVVVTDSQNNIISPAGGTLPLSIPDDADSFARMNVYPVS
                     TTGVPPETGSFEATATVRINFD"
     gene            5217..5759
                     /locus_tag="IRB70_000823"
     CDS             5217..5759
                     /locus_tag="IRB70_000823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630772.1"
                     /translation="MKKNTIFQVVILSFTLLYMHVGIAGPEQVSMHIYGNVVDQGCDV
                     ATKSALQNIHIGDFNISDFQTANTVSTAADLNIDITGCAAGITGADVLFSGEADTLVP
                     TLLKLTDTGGSGGMATGIAVQILDAQSQQEIPLNQVLPLTPLKAGDNTLKYQLRYKST
                     KAGATGGNATAVLYFDLVYQ"
     gene            5767..6282
                     /locus_tag="IRB70_000824"
     CDS             5767..6282
                     /locus_tag="IRB70_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415463.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBC0630773.1"
                     /translation="MLKQIIWILFLLGLTGGCELFAHDGTVNISGSFRRNTCVLAQDS
                     KQINVQLGDVSLTRFSHGNYGPEKSFIINLQDCGTDVSTVDVTFSGTPDGVQSEMLSI
                     ESGTDAASGLAIAILDDAKILIPLNQASKDYSLHSGKVPLTFYAQLRPVNSDVQSGKV
                     NASATFVLHYD"
     gene            6248..6985
                     /locus_tag="IRB70_000825"
     CDS             6248..6985
                     /locus_tag="IRB70_000825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HBC0630774.1"
                     /translation="MPARHLYFIMTNTWNRLALLIFAVLSLLVASELQAGVVVGGTRF
                     IFPADRDSISILLTNTSQESWLINSKINRPTRWAGDEASTVPAPLLAAPPLILLKPGT
                     TGTLRLLRTESDILPVDRETLFELSIASVPSGKVENQSVKVAMRSVFKLFWRPEGLPG
                     DPLEAYQQLRWTRNSQGVQLTNPTPYYINLIQVSVNGKALSNAGVVPPKSQRQTSWCQ
                     AITPCHVSWRTINDYGGLSAKKEQNLP"
     gene            7096..8106
                     /gene="pyrD"
                     /locus_tag="IRB70_000826"
     CDS             7096..8106
                     /gene="pyrD"
                     /locus_tag="IRB70_000826"
                     /EC_number="1.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent dihydroorotate dehydrogenase"
                     /protein_id="HBC0630775.1"
                     /translation="MYYPFVRKALFQLDPERAHEFTFQQLRRITGTPFEALVRQKVPA
                     KPVNCMGLTFKNPLGLAAGLDKDGECIDALGAMGFGSIEIGTVTPRPQPGNDKPRLFR
                     LVDAEGLINRMGFNNLGVDNLVENVKKAHYDGVLGINIGKNKDTPVEQGKDDYLICME
                     KIYAYAGYIAINISSPNTPGLRTLQYGEALDDLLTAIKNKQNDLQEMHHKYVPIAVKI
                     APDLSEEELIQVADSLVRHNIDGVIATNTTLDRSLVQGMKNCDQTGGLSGRPLQLKST
                     EIIRRLSQELNGRLPIIGVGGIDSVIAAREKIAAGASLVQIYSGFIFKGPPLIKEIVT
                     HI"
     gene            8280..8822
                     /gene="zapC"
                     /locus_tag="IRB70_000827"
     CDS             8280..8822
                     /gene="zapC"
                     /locus_tag="IRB70_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415466.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapC"
                     /protein_id="HBC0630776.1"
                     /translation="MRIKPDDNWRWYYDEEHDRMMLDLANGMLFRSRFARKMLTPDAF
                     SPAGFCVDDAALYFSFEEKCRDFNLSKEQKAELVLNALVAIRYLKPQMPKSWHFVSHG
                     EMWVPMPGDAACVWLSDTHEQVNLLVVESGENAALCLLAQPCVVIAGRAMQLGDAIKI
                     MNDRLKPQVNVDSFSLEQAV"
     gene            complement(8819..9928)
                     /gene="ycbX"
                     /locus_tag="IRB70_000828"
     CDS             complement(8819..9928)
                     /gene="ycbX"
                     /locus_tag="IRB70_000828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein YcbX"
                     /protein_id="HBC0630777.1"
                     /translation="MATLTRLFIHPVKSMRGIGLTHALADVSGLAFDRIFMITEPDGT
                     FITARQFPQMVRFIPSPVHDGLHLTAPDGSSAYVRFADFATQDAPTEVWGTHFTARIA
                     PDAINKWLSGFFSREVQLRWVGPQMTRRVKRHNTVPLSFADGYPYLLANEASLRDLQQ
                     RCPASVKMEQFRPNLVVSGASTWEEDSWKVIRIGDVVFDVVKPCSRCIFTTVSPEKGQ
                     KHPAGEPLKTLQSFRTAQDNGDVDFGQNLIARNSGVIRVGDEVEILATAPAKIYGTGA
                     ADDTANITQQPDANVDIDWQGQAFRGNNQQVLLEQLENQGIRIPYSCRAGICGSCRVQ
                     LLEGEVTPLKKSAMGDDGTILCCSCVPKTALKLTR"
     gene            10026..12134
                     /gene="rlmKL"
                     /locus_tag="IRB70_000829"
     CDS             10026..12134
                     /gene="rlmKL"
                     /locus_tag="IRB70_000829"
                     /EC_number="2.1.1.173"
                     /EC_number="2.1.1.264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 23S rRNA
                     (guanine(2069)-N(7))-methyltransferase RlmK/23S rRNA
                     (guanine(2445)-N(2))-methyltransferase RlmL"
                     /protein_id="HBC0630778.1"
                     /translation="MNSLFASTARGLEELLKTELENLGAVECQVVQGGVHFKGDTRLV
                     YQSLMWSRLASRIMLPLGECKVYSDLDLYLGVQAINWTEMFNPGATFAVHFSGLNDTI
                     RNSQYGAMKVKDAIVDTFTRKNLPRPNVDRDAPDIRVNVWLHKETASIALDLSGDGLH
                     LRGYRDRAGIAPIKETLAAAIVMRSGWQPGTPLLDPMCGSGTLLIEAAMLATDRAPGL
                     HRGRWGFSGWAQHDEAIWQEVKAEAQTRARKGLAEYSSHFYGSDSDARVIQRARTNAR
                     LAGIGELITFEVKDVAQLTNPLPKGPYGTVLSNPPYGERLDSEPALIALHSLLGRIMK
                     NQFGGWNLSLFSASPDLLSCLQLRADKQYKAKNGPLDCVQKNYHVAESTPDSKPAMVA
                     EDYANRLRKNLKKFEKWARQEGIECYRLYDADLPEYNVAVDRYADWVVVQEYAPPKTI
                     DAHKARQRLFDIIAATISVLGIAPNKLVLKTRERQKGKNQYQKLGEKGEFLEVTEYNA
                     HLWVNLTDYLDTGLFLDHRIARRMLGQMSKGKDFLNLFSYTGSATVHAGLGGARSTTT
                     VDMSRTYLEWAERNLRLNGLTGRAHRLIQADCLAWLREANEQFDLIFIDPPTFSNSKR
                     MEDAFDVQRDHLALMKDLKRLLRAGGTIMFSNNKRGFRMDLDGLAKLGLKAQEITQKT
                     LSQDFARNRQIHNCWLITAA"
     gene            12146..14053
                     /locus_tag="IRB70_000830"
     CDS             12146..14053
                     /locus_tag="IRB70_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0630779.1"
                     /translation="MSLISMHGAWLSFSDVPLLDNAELHIEDNERVCLVGRNGAGKST
                     LMKILNREQGLDDGRIIYEQDLIVARLQQDPPRNVEGSVYDFVAEGIEEQAEYLKRYH
                     DISRLVMNDPSEKNLNELAKVQEQLDHHNLWQLENRINEVLAQLGLDPNVALSSLSGG
                     WLRKAALGRALVSNPRVLLLDEPTNHLDIETIDWLEGFLKTFNGTIIFISHDRSFIRN
                     MATRIVDLDRGKLVTYPGNYDQYLLEKEEALRVEELQNAEFDRKLAQEEVWIRQGIKA
                     RRTRNEGRVRALKAMRRERSQRREVMGTAKMQVEEASRSGKIVFEMEDVCYQVDGKQL
                     VKDFSAQVLRGDKIALIGPNGCGKTTLLKLMLGQLQADSGRIHVGTKLEVAYFDQHRA
                     ELDPDKTVMDNLAEGKQEVMVNGKPRHVLGYLQDFLFHPKRAMTPVRALSGGERNRLL
                     LARLFLKPSNLLILDEPTNDLDVETLELLEELIDSYQGTVLLVSHDRQFVDNTVTECW
                     IFEGGGKIGRYVGGYHDARGQQEQYVALKQPAVKKTEEAAAAKAETVKRSSSKLSYKL
                     QRELEQLPQLLEDLEAKLEALQTQVADASFFSQPHEQTQKVLADMAAAEQELEQAFER
                     WEYLEALKNGG"
     gene            14183..15436
                     /gene="pqiA"
                     /locus_tag="IRB70_000831"
     CDS             14183..15436
                     /gene="pqiA"
                     /locus_tag="IRB70_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiA"
                     /protein_id="HBC0630780.1"
                     /translation="MCEHHHAAKHILCSQCDMLVALPRLEHGQKAACPRCGTTLTVAW
                     DAPRQRPTAYALAALFMLLLSNLFPFVNMNVAGVTSEITLLEIPGVLFSEDYASLGTF
                     FLLFVQLVPAFCLITILLLVNRAELPVRLKEQLARVLFQLKTWGMAEIFLAGVLVSFV
                     KLMAYGSIGVGSSFLPWCLFCVLQLRAFQCVDRRWLWDDIAPMPELRQPLKPGVTGIR
                     QGLRSCSCCTAILPADEPVCPRCSTKGYVRRRNSLQWTLALLVTSIMLYLPANILPIM
                     VTDLLGSKMPSTILAGVILLWSEGSYPVAAVIFLASIMVPTLKMIAIAWLCWDAKGHG
                     KRDSERMHLIYEVVEFVGRWSMIDVFVIAVLSALVRMGGLMSIYPAMGALMFALVVIM
                     TMFSAMTFDPRLSWDRQPESEHEES"
     gene            15441..17081
                     /gene="pqiB"
                     /locus_tag="IRB70_000832"
     CDS             15441..17081
                     /gene="pqiB"
                     /locus_tag="IRB70_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706874.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intermembrane transport protein PqiB"
                     /protein_id="HBC0630781.1"
                     /translation="MESNNGEAKIQKVKNWSPVWIFPIVTALIGAWVLFYHYSHQGPE
                     VTLITANAEGIEGGKTTIKSRSVDVGVVESATLADDLTHVEIKARLNSGMEKLLHKDT
                     VFWVVKPQIGREGISGLGTLLSGVYIELQPGAKGSKMDKYDLLDSPPLAPPDAKGIRV
                     ILDSKKAGQLSPGDPVLFRGYRVGSVETSTFDTQKRNISYQLFINAPYDRLVTSNVRF
                     WKDSGIAVDLTSAGMRVEMGSLTTLLSGGVSFDVPEGLDLGQPVAPKTAFVLYDDQKS
                     IQDSLYTDHIDYLMFFKDSVRGLQPGAPVEFRGIRLGTVSKVPFFAPNMRQTFNDDYR
                     IPVLIRIEPERLKMQLGENADVVEHLGELLKRGLRGSLKTGNLVTGALYVDLDFYPNT
                     PAITGIREFNGYQIIPTVSGGLAQIQQRLMEALDKINKLPLNPMIEQATSTLSESQRT
                     MKNLQTTLDSMNKILASQSMQQLPTDMQSTLRELNRSMQGFQPGSAAYNKMVADMQRL
                     DQVLRELQPVLKTLNEKSNALVFEAKDKKDPEPKRAKQ"
     gene            17078..17641
                     /gene="pqiC"
                     /locus_tag="IRB70_000833"
     CDS             17078..17641
                     /gene="pqiC"
                     /locus_tag="IRB70_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309063.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity-associated transporter
                     subunit PqiC"
                     /protein_id="HBC0630782.1"
                     /translation="MKKWLVTIAALWLAGCSSGEINKNYYQLPVVQSGTQSTASQGNR
                     LLWVEQVAVPDYLAGNGVVYQTSDVKYVIANNNLWASPLDQQLRNTLVANLSTQLPGW
                     VVASQPLGSAQDTLNVTVTEFNGRYDGKVIVSGEWLLNHQGQLIKRPFRLEGVQTQDG
                     YDEMVKVLASVWSQEAASIAQEIKRLP"
     gene            17897..18064
                     /gene="rmf"
                     /locus_tag="IRB70_000834"
     CDS             17897..18064
                     /gene="rmf"
                     /locus_tag="IRB70_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome modulation factor"
                     /protein_id="HBC0630783.1"
                     /translation="MKRQKRDRLERAHQRGYQAGIAGRSKEMCPYQTLNQRSQWLGGW
                     REAMADRVVMA"
     gene            complement(18134..18652)
                     /gene="fabA"
                     /locus_tag="IRB70_000835"
     CDS             complement(18134..18652)
                     /gene="fabA"
                     /locus_tag="IRB70_000835"
                     /EC_number="4.2.1.59"
                     /EC_number="5.3.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014915875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-hydroxydecanoyl-ACP
                     dehydratase/trans-2-decenoyl-ACP isomerase"
                     /protein_id="HBC0630784.1"
                     /translation="MVDKRESYTKEDLLASGRGELFGAKGPQLPAPNMLMMDRVVKMT
                     ETGGNFDKGYVEAELDINPDLWFFGCHFIGDPVMPGCLGLDAMWQLVGFYLGWLGGEG
                     KGRALGVGEVKFTGQVLPTAKKVTYRIHFKRIVNRRLIMGLADGEVLVDGRLIYTASD
                     LKVGLFQDTSAF"
     gene            complement(18721..20481)
                     /locus_tag="IRB70_000836"
     CDS             complement(18721..20481)
                     /locus_tag="IRB70_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Lon protease family protein"
                     /protein_id="HBC0630785.1"
                     /translation="MTITKLAWRDLVPDTDSYQEIFAQPHLIDENDPLFSDTQPRLQF
                     ALEQLLHTRASSSFMLAKAPEESEYLNLIADAARALQSDAGQLVGCHYEVSGHTIRLR
                     NAVSADDNFATLTQVVAADWVEAEQLFGCLRQFNGDITLQPGLVHQANGGILIISLRT
                     LLAQPLLWMRLKNIVNRERFDWVAFDESRPLPVSVPSMPLKLKVILVGERESLADFQE
                     MEPELSEQAIYSEFEDTLQIVDAESVSQWCRWVTLTARHNHLPAPGADAWPVLIREAA
                     RYTGEQETLPLSPQWILRQCKEVASLCDGDTFSGEQLNLMLQQREWREGFLAERMQDE
                     ILQEQILIETEGERIGQINALSVIEFPGHPRAFGEPSRISCVVHIGDGEFTDIERKAE
                     LGGNIHAKGMMIMQAFLMSELQLEQQIPFSASLTFEQSYSEVDGDSASMAELCALISA
                     LADVPVNQSIAITGSVDQFGRAQPVGGLNEKIEGFFAICQQRELTGKQGVIIPTANVR
                     HLSLHSELVKAVEEGKFTIWAVDDVTDALPLLLNLVWDGEGQTTLMQTIQERIAQASQ
                     QEGRHRFPWPLRWLNWFIPN"
     gene            20667..21119
                     /gene="matP"
                     /locus_tag="IRB70_000837"
     CDS             20667..21119
                     /gene="matP"
                     /locus_tag="IRB70_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ter protein MatP"
                     /protein_id="HBC0630786.1"
                     /translation="MKYQQLENLESGWKWKYLVKKHREGELITRYIEASAAQEAVDVL
                     LSLENEPVLVNGWIDKHMNPELVNRMKQTIRARRKRHFNAEHQHTRKKSIDLEFIVWQ
                     RLAGLAQRRGKTLSETIVQLIEDAENKEKYANKMSSLKQDLQALLGKE"
     gene            complement(21196..22236)
                     /gene="ompA"
                     /locus_tag="IRB70_000838"
     CDS             complement(21196..22236)
                     /gene="ompA"
                     /locus_tag="IRB70_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpA"
                     /protein_id="HBC0630787.1"
                     /translation="MKKTAIAIAVALAGFATVAQAAPKDNTWYTGAKLGWSQYHDTGF
                     INNNGPTHENQLGAGAFGGYQVNPYVGFEMGYDWLGRMPYKGDNINGAYKAQGVQLTA
                     KLGYPITDDLDVYTRLGGMVWRADTKSNVYGKNHDTGVSPVFAGGVEYAITPEIATRL
                     EYQWTNNIGDAHTIGTRPDNGMLSLGVSYRFGQGEAAPVVAPAPAPAPEVQTKHFTLK
                     SDVLFTFNKATLKPEGQAALDQLYSQLSNLDPKDGSVVVLGYTDRIGSDAYNQALSER
                     RAQSVVDYLISKGIPADKISARGMGESNPVTGNTCDNVKQRAALIDCLAPDRRVEIEV
                     KGIKDVVTQPQA"
     gene            complement(22593..23102)
                     /gene="sulA"
                     /locus_tag="IRB70_000839"
     CDS             complement(22593..23102)
                     /gene="sulA"
                     /locus_tag="IRB70_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor SulA"
                     /protein_id="HBC0630788.1"
                     /translation="MYTSGYAHRSSSFSSAASKIARVSTENTTAGLISEVVYREDQPM
                     MTQLLLLPLLQQLGQQSRWQLWLTPQQKLSREWVLASGLPLTKVMQISQLSPCHTVES
                     MVRALRTGNYSVVIGWLADDLTEEEHAELVDAANEGNAMGFIMRPVSASSHATRQLSG
                     LKIHSNLYH"
     gene            23321..23950
                     /gene="sxy"
                     /locus_tag="IRB70_000840"
     CDS             23321..23950
                     /gene="sxy"
                     /locus_tag="IRB70_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CRP-S regulon transcriptional coactivator Sxy"
                     /protein_id="HBC0630789.1"
                     /translation="MKSLSYKRIYKSQEYLATLGTIEYRSLFGSYSLTVDDTVFAMVS
                     DGELYLRACEQSAQYCVKHPPVWLTYKKCGRSVTLNYYRVDESLWRNQLKLVRLSKYS
                     LDAALKEKSTRNTRERLKDLPNMSFHLEAILGEVGIKDVRALRILGAKMCWLRLRQQN
                     SLVTEKILFMLEGAIIGIHEAALPVARRQELAEWADSLTPKQEFPAELE"
     gene            complement(23913..26075)
                     /gene="yccS"
                     /locus_tag="IRB70_000841"
     CDS             complement(23913..26075)
                     /gene="yccS"
                     /locus_tag="IRB70_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309071.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01666 family membrane protein"
                     /protein_id="HBC0630790.1"
                     /translation="MAFMLSPLLKRYTWNSAWLYYARIFIALCGTTAFPWWLGDVKLT
                     IPLTLGMVAAALTDLDDRLAGRLRNLIITLFCFFIASASVELLFPWPWLFAIGLTLST
                     SGFILLGGLGQRYATIAFGALLIAIYTMLGTSLYEHWYQQPMYLLAGAVWYNVLTLIG
                     HLLFPVRPLQDNLARCYEQLARYLELKSRMFDPDIEDESQAPLYDLALANGQLMATLN
                     QTKLSLLTRLRGDRGQRGTRRTLHYYFVAQDIHERASSSHIQYQTLREHFRHSDVLFR
                     FQRLMSMQGQACQQLSRCILLRQPYQHDPHFERAFTHIDAALERMRDNGAPADLLKTL
                     GFLLNNLRAIDAQLATIESEQAQALPHNNDENELADDSPHGLSDIWLRLSRHFTPESA
                     LFRHAVRMSLVLCFGYAIIQITGMHHGYWILLTSLFVCQPNYNATRHRLKLRIIGTLV
                     GIAIGIPVLWFVPSLEGQLVLLVITGVLFFAFRNVQYAHATMFITLLVLLCFNLLGEG
                     FEVALPRVIDTLIGCAIAWAAVSYIWPDWKFRNLPRMLERATEANCRYLDAILEQYHQ
                     GRDNRLAYRIARRDAHNRDAELASVVSNMSSEPNVTPQIREAAFRLLCLNHTFTSYIS
                     ALGAHREQLTNPEILAFLDDAVCYVDDALHHQPADEERVNQALAGLKQRMQQLEPRAD
                     SKEPLVVQQVGLLIALLPEIGRLQRQITQVPQETPVSA"
     gene            complement(26085..26531)
                     /locus_tag="IRB70_000842"
     CDS             complement(26085..26531)
                     /locus_tag="IRB70_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBC0630791.1"
                     /translation="MRTVLNILNFVLGGFATTLGWLLATLVSIVLIFTLPLTRSCWEI
                     TKLSLVPYGNEAIHVDELNPAGKNVLLNTGGTVLNIFWLIFFGWWLCLMHIATGIAQC
                     ISIIGIPVGIANFKIAAIALWPVGRRVVSVETAQAAREANARRRFE"
     gene            26654..28708
                     /gene="helD"
                     /locus_tag="IRB70_000843"
     CDS             26654..28708
                     /gene="helD"
                     /locus_tag="IRB70_000843"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase IV"
                     /protein_id="HBC0630792.1"
                     /translation="MELKATTLGKRLAQHPYDRAVILNAGIKVSGDRHEYLIPFNQLL
                     AIHCKRGLVWGELEFVLPDEKVVRLHGTEWGETQRFYHHLDTHWRRWSGEMSEIASGV
                     LRQQLDLIATRTGENKWLTREQTSGVQQQIRQALSALPLPVNRLEEFDNCREAWRKCQ
                     AWLKDIEGARLQHNQAYTEAMLTEYADFFRQVESSPLNPAQARAVVNGEHSLLVLAGA
                     GSGKTSVLVARAGWLLARGEASPEQILLLAFGRKAAEEMDERIRERLHTEDITARTFH
                     ALALHIIQQGSKKVPIVSKLENDTAARHELFIAEWRKQCSEKKAQAKGWRQWLTEEMQ
                     WSVPEGNFWDDEKLQRRLASRLDRWVSLMRMHGGAQAEMIASAPEEIRDLFSKRIKLM
                     APLLKAWKGALKAENAVDFSGLIHQAIVILEKGRFISPWKHILVDEFQDISPQRAALL
                     AALRKQNSQTTLFAVGDDWQAIYRFSGAQMSLTTAFHENFGEGDRCDLDTTYRFNSRI
                     GEVANRFIQQNPGQLKKPLNSLTNGDKKAVTLLDESHLDALLDKLSGYAKPEERILIL
                     ARYHHMRPASLEKAATRWPKLQIDFMTIHASKGQQADYVIIVGLQEGSDGFPAAARES
                     IMEEALLPPVEDFPDAEERRLMYVALTRARHRVWALFNKENPSPFVEILKNLDVPVAR
                     KP"
     gene            complement(28740..29198)
                     /gene="mgsA"
                     /locus_tag="IRB70_000844"
     CDS             complement(28740..29198)
                     /gene="mgsA"
                     /locus_tag="IRB70_000844"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBC0630793.1"
                     /translation="MELTTRTLPARKHIALVAHDHCKQMLMSWVERHQPLLEQHVLYA
                     TGTTGNLISRATGMNVNAMLSGPMGGDQQVGALISEGKIDVLIFFWDPLNAVPHDPDV
                     KALLRLATVWNIPVATNVATADFIIQSPHFNDAVDILIPDYQRYLADRLK"
     gene            complement(29294..29956)
                     /locus_tag="IRB70_000845"
     CDS             complement(29294..29956)
                     /locus_tag="IRB70_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2057 family protein"
                     /protein_id="HBC0630794.1"
                     /translation="MKTGIVTTLIALCLPVSVFATTLRLSTDVDLLVLDGKKVSSSLL
                     RGADSIELDNGPHQLVFRVEKTIHLSNSEERLYISPPLVVSFNTQLINQVNFRLPRLE
                     NEREANHFDAAPRLELLDGDATPIPVKLDILAITSTAKTIDYEVEVERYNKSAKRASL
                     PQFATMMADDSTLLSGVSELDAIPPQSQVLTEQRLKYWFKLADPQTRNTFLQWAEKQP
                     SS"
     gene            30129..30542
                     /locus_tag="IRB70_000846"
     CDS             30129..30542
                     /locus_tag="IRB70_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBC0630795.1"
                     /translation="MKETDIAGILTSTHTIALVGASDKPDRPSYRVMKYLLDQGYHVI
                     PVSPKVAGKTLLGQQGYGTLAEVPEKVDMVDVFRNSEAAWGVAQEAIAIGAKTLWMQL
                     GVINEQAAVLARDAGLNVVMDRCPAIEIPRLGLAK"
     gene            complement(30587..30904)
                     /gene="hspQ"
                     /locus_tag="IRB70_000847"
     CDS             complement(30587..30904)
                     /gene="hspQ"
                     /locus_tag="IRB70_000847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock protein HspQ"
                     /protein_id="HBC0630796.1"
                     /translation="MIASKFGIGQQVRHSLLGYLGVVVDIDPVYSLSEPSPDELAVND
                     ELRAAPWYHVVMEDDNGLPVHTYLAEAQLSSELQDEHPEQPSMDELAQTIRKQLQAPR
                     LRN"
     gene            complement(30962..32152)
                     /gene="rlmI"
                     /locus_tag="IRB70_000848"
     CDS             complement(30962..32152)
                     /gene="rlmI"
                     /locus_tag="IRB70_000848"
                     /EC_number="2.1.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415487.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytosine(1962)-C(5))-methyltransferase
                     RlmI"
                     /protein_id="HBC0630797.1"
                     /translation="MSVRLVLAKGREKSLLRRHPWIFSGAVARMEGKASLGETIDIVD
                     HQGKWLARGAYSPASQIRARVWTFDPNESIDIAFFTRRLQQAQKWRDWLAQKDGLNSY
                     RLIAGESDGLPGITIDRFGNFLVLQLLSAGAEYQRAALISALQTLYPECAIYDRSDVA
                     VRKKEGMELTQGPVTGELPPALLPIEEHGMKLLVDIQHGHKTGYYLDQRDSRLATRRY
                     VENKRVLNCFSYTGGFAVSALMGGCSQVVSVDTSQEALDIARQNVELNKLDLSKAEFV
                     RDDVFKLLRTYRDRGEKFDVIVMDPPKFVENKSQLMGACRGYKDINMLAIQLLNEGGV
                     LLTFSCSGLMTSDLFQKIIADAAIDAGRDVQFIEQFRQAADHPVIATYPEGLYLKGFA
                     CRVM"
     gene            32247..32525
                     /gene="yccX"
                     /locus_tag="IRB70_000849"
     CDS             32247..32525
                     /gene="yccX"
                     /locus_tag="IRB70_000849"
                     /EC_number="3.6.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBC0630798.1"
                     /translation="MSKVCIIAWVYGRVQGVGFRYTTQYEAKKLGLTGYAKNLDDGSV
                     EVVACGEEGQVEKLMQWLKSGGPRSARVERVLSEPHHPSGELTDFRIR"
     gene            complement(32522..32851)
                     /gene="tusE"
                     /locus_tag="IRB70_000850"
     CDS             complement(32522..32851)
                     /gene="tusE"
                     /locus_tag="IRB70_000850"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309080.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusE"
                     /protein_id="HBC0630799.1"
                     /translation="MLIFEGKEIETDTEGYLKESSQWSEPLAVVIAENEGIALSPEHW
                     EVVRFVRDFYLEFNTSPAIRMLVKAMANKFGEEKGNSRYLYRLFPKGPAKQATKIAGL
                     PKPVKCI"
     gene            complement(32943..33602)
                     /gene="yccA"
                     /locus_tag="IRB70_000851"
     CDS             complement(32943..33602)
                     /gene="yccA"
                     /locus_tag="IRB70_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000375124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease modulator YccA"
                     /protein_id="HBC0630800.1"
                     /translation="MDRIVSSSHDRTSLLSTHKVLRNTYFLLSLTLAFSAITATASTV
                     LMLPSPGLILTLVGMYGLMFLTYKTANKPTGIISAFAFTGFLGYILGPILNTYLSAGM
                     GDVIAMALGGTALVFFCCSAYVLTTRKDMSFLGGMLMAGIVVVLIGMVANIFLQLPAL
                     HLAISAVFILISSGAILFETSNIIHGGETNYIRATVSLYVSLYNIFVSLLSILGFASR
                     D"
     gene            complement(33809..33896)
                     /locus_tag="IRB70_000852"
     tRNA            complement(33809..33896)
                     /locus_tag="IRB70_000852"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(33860..33862),aa:Ser,seq:tga)
     gene            34322..35440
                     /gene="hyaA"
                     /locus_tag="IRB70_000853"
     CDS             34322..35440
                     /gene="hyaA"
                     /locus_tag="IRB70_000853"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 small subunit"
                     /protein_id="HBC0630801.1"
                     /translation="MNNEETFYQAMRRQGVTRRSFLKYCSLAATSLGLGAGMAPKIAW
                     ALENKPRIPVVWIHGLECTCCTESFIRSAHPLAKDVILSLISLDYDDTLMAAAGTQAE
                     EVFEDIITQYNGKYILAVEGNPPLGEQGMFCISSGRPFIEKLKRAAAGASAIIAWGTC
                     ASWGCVQAARPNPTQATPIDKVITDKPIIKVPGCPPIPDVMSAIITYMVTFDRLPDVD
                     RMGRPLMFYGQRIHDKCYRRAHFDAGEFVQSWDDDAARKGYCLYKMGCKGPTTYNACS
                     STRWNDGVSFPIQSGHGCLGCAENGFWDRGSFYSRVVDIPQMGTHSTADTVGLTALGV
                     VAAAVGVHAVASAVDQRRRHNQQPTETEHQPGNEDKQA"
     gene            35437..37230
                     /gene="hyaB"
                     /locus_tag="IRB70_000854"
     CDS             35437..37230
                     /gene="hyaB"
                     /locus_tag="IRB70_000854"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase large subunit"
                     /protein_id="HBC0630802.1"
                     /translation="MSTQYETQGYTINNAGRRLVVDPITRIEGHMRCEVNINDQNVIT
                     NAVSCGTMFRGLEIILQGRDPRDAWAFVERICGVCTGVHALASVYAIEDAIGIKVPDN
                     ANIIRNIMLATLWCHDHLVHFYQLAGMDWIDVLDALKADPRKTSELAQSLSSWPKSSP
                     GYFFDVQNRLKKFVEGGQLGIFRNGYWGHPQYKLPPEANLMGFAHYLEALDFQREIVK
                     IHAVFGGKNPHPNWIVGGMPCAINIDESGAVGAVNMERLNLVQSIITRTADFINNVMI
                     PDALAIGQFNKPWSEIGTGLSDKCVLSYGAFPDIANDFGEKSLLMPGGAVINGDFNNV
                     LPVDLVDPQQVQEFVDHAWYRYPNDQVGRHPFDGITDPWYNPGDVKGSDTNIQQLNEQ
                     ERYSWIKAPRWRGNAMEVGPLARTLIAYHKGDAATVESVDRMMSALNLPLSGIQSTLG
                     RILCRAHEAQWAAGKLQYFFDKLMTNLKNGNLATASTEKWEPATWPTECRGVGFTEAP
                     RGALGHWAAIRDGKIDLYQCVVPTTWNASPRDPKGQIGAYEAALMNTKMAIPEQPLEI
                     LRTLHSFDPCLACSTHVLGDDGSELISVQVR"
     gene            37249..37956
                     /gene="hyaC"
                     /locus_tag="IRB70_000855"
     CDS             37249..37956
                     /gene="hyaC"
                     /locus_tag="IRB70_000855"
                     /EC_number="1.12.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase b-type cytochrome subunit"
                     /protein_id="HBC0630803.1"
                     /translation="MQQKSDNVVSHYVFEAPVRIWHWLTVLCMAVLMVTGYFIGKPLP
                     SVSGEATYLFYMGYIRLIHFSAGMIFTVVLLMRIYWAFVGNRYSRELFIVPVWRKSWW
                     QGVWYEIRWYLFLAKRPSADIGHNPIAQAAMFGYFLMSVFMIITGFALYSEHSQYAIF
                     APFRYVVEFFYWTGGNSMDIHSWHRLGMWLIGAFVIGHVYMALREDIMSDDTVISTMV
                     NGYRSHKFGKISNKERS"
     gene            37953..38540
                     /locus_tag="IRB70_000856"
     CDS             37953..38540
                     /locus_tag="IRB70_000856"
                     /EC_number="3.4.23.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 1 maturation protease"
                     /protein_id="HBC0630804.1"
                     /translation="MSEQRVVVMGLGNLLWADEGFGVRVAERLYAHYHWPDEVEIVDG
                     GTQGLNLLGYVESASHLLILDAIDYGLEPGTLRTYAGERIPAYLSAKKMSLHQNSFSE
                     VLALADIRGNLPAHIALVGLQPAMLDDYGGSLSELAREQLPAAEQAALVQLAAWGIVP
                     QPTEELRCLNYDCLSMENYEGVRLRQYKMRLEEQG"
     gene            38537..38935
                     /gene="hyaE"
                     /locus_tag="IRB70_000857"
     CDS             38537..38935
                     /gene="hyaE"
                     /locus_tag="IRB70_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-1 operon protein HyaE"
                     /protein_id="HBC0630805.1"
                     /translation="MSNDTPFDALWQRMLARGWTPISESRLDDWLTQAPDGVVLLSSD
                     PKRTPEVSDNPVMIGELLREFPDYTWQVAIADLEQSEAIGDRFGVFRFPATLVFTGGN
                     YRGVLNGIHPWAELINLMRGLVEPQQERAS"
     gene            38932..39789
                     /locus_tag="IRB70_000858"
     CDS             38932..39789
                     /locus_tag="IRB70_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase expression/formation protein"
                     /protein_id="HBC0630806.1"
                     /translation="MSETFFHLLGPGTQPNDDSFSMNPLPITCQVNDEPSMAALEQCA
                     HSPQVIALLNELQHQLSERQPPLGEVLAVDLLNLNADDRHFINTLLGEGEVSVRIQQA
                     DDSESEIQEAIFCGLWRVRRRRGDKLLEDKLEAGCAPLALWQAATQNVLPTDSLLPPP
                     IDGLMNGLPLAHELLAHVRNPDAQPHSINLTQLPISEADRLFLSRLCGPGNIQIRTIG
                     YGESYINATGLRHVWHLRCTDTLKGPLLESYEICPIPEVVLAAPEDLVDSAQRLSEVC
                     QWLAEGAPT"
     gene            39923..41467
                     /gene="appC"
                     /locus_tag="IRB70_000859"
     CDS             39923..41467
                     /gene="appC"
                     /locus_tag="IRB70_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit 1"
                     /protein_id="HBC0630807.1"
                     /translation="MWDVIDLSRWQFALTALYHFLFVPLTLGLIFLLAIMETIYVVTG
                     KTIYRDMTRFWGKLFGINFALGVATGLTMEFQFGTNWSFYSNYVGDIFGAPLAMEALM
                     AFFLESTFVGLFFFGWQRLNKYQHLLVTWLVAFGSNLSALWILNANGWMQYPTGAHFD
                     IDTLRMEMTSFSELVFNPVSQVKFVHTVMAGYVTGAMFIMAISAWYLLRGRERDVALR
                     SFAIGSVFGTLAIIGTLQLGDSSAYEVAQVQPVKLAAMEGEWQTEPAPAPFHVVAWPE
                     QDQERNAFAIKIPALLGILATHSLDKPVPGLKNLMAETYPRLQRGRMAWLLMQEISQG
                     NREPHVLQAFRELEGDLGYGMLLSRYAPDMNHVTATQYQAAMRGAIPQVAPVFWSFRI
                     MVGCGSLLLLVMLIALVQTLRGKIDQHRWVLKMALWSLPLPWIAIEAGWFMTEFGRQP
                     WAIQDILPTYSAHSALTTGQLAFSLIMIVGLYTLFLIAEVYLMQKYARLGPSAMQSEQ
                     PTQQQG"
     gene            41479..42615
                     /gene="appB"
                     /locus_tag="IRB70_000860"
     CDS             41479..42615
                     /gene="appB"
                     /locus_tag="IRB70_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HBC0630808.1"
                     /translation="MFDYETLRFIWWLLIGVILVVFMVSDGFDMGIGCLLPLVARNDD
                     ERRIVINSVGAHWEGNQVWLILAGGALFAAWPRVYAAAFSGFYVAMILVLCSLFFRPL
                     AFDYRGKIADARWRKMWDAGLVIGSLVPPVVFGIAFGNLLLGVPFAFTPQLRVEYLGS
                     FWQLLTPFPLLCGLLSLGMVILQGGVWLQLKTVGVIHLRSQLATKRAALLVMLCFLLA
                     GYWLWVGIDGFVLLAQDANGPSNPLMKLVAVLPGAWMNNFVESPVLWIFPLLGFFCPL
                     LTVMAIYRGRPGWGFLMASLMQFGVIFTAGITLFPFVMPSSVSLISSLTLWDSTSSQL
                     TLSIMLVIVLIFLPIVLLYTLWSYYKMWGRMTTETLRRNENELY"
     gene            42628..42720
                     /gene="cbdX"
                     /locus_tag="IRB70_000861"
     CDS             42628..42720
                     /gene="cbdX"
                     /locus_tag="IRB70_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-II oxidase subunit CbdX"
                     /protein_id="HBC0630809.1"
                     /translation="MWYLLWFVGILLMCSLSTLVLVWLDPRLKS"
     gene            42800..44110
                     /gene="appA"
                     /locus_tag="IRB70_000862"
     CDS             42800..44110
                     /gene="appA"
                     /locus_tag="IRB70_000862"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001623747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acid phosphatase/4-phytase"
                     /protein_id="HBC0630810.1"
                     /translation="MKAILIPFLSLLIPFTPQSAFAQSEPELKLESVVIVSRHGVRAP
                     TKATQLMQDVTPDAWPTWPVKLGWLTPRGGELIAYLGHYQRQRLVADGLLTKKGCPQP
                     GQVAIIADVDERTRKTGEAFAAGLAPDCAITVHTQADTSSPDPLFNPLKNGVCQLDNA
                     NVTDAILSRAGGSIADFTGHRQTAFRELEQVLNFPQSNLCLNREKQDKSCSLTQALPS
                     ELKVSADNVSLTGAVSLASMLTEIFLLQQAQGMPEPGWGRITDSHQWNTLLSLHNAQF
                     YLLQRTPEVARSRATPLLDLIMAALTPHPPQKQAYGVTLPTSVLFIAGHDTNLANLGG
                     ALELNWTLPGQPDNTPPGGELVFERWRRLSDNSQWIQVSLVFQTLQQMRDKTPLSLNT
                     PPGEVKLTLAGCEERNAQGMCSLAGFTQIVNEARIPACALHQDK"
     gene            complement(44098..44310)
                     /gene="cspH"
                     /locus_tag="IRB70_000863"
     CDS             complement(44098..44310)
                     /gene="cspH"
                     /locus_tag="IRB70_000863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspH"
                     /protein_id="HBC0630811.1"
                     /translation="MSRKMTGIVKTFDRKSGKGFIIPSDGRKEVQVHISAFTPRDAEV
                     LIPGLRVEFCRVNGLRGPTAANVYLS"
     gene            44596..44808
                     /gene="cspG"
                     /locus_tag="IRB70_000864"
     CDS             44596..44808
                     /gene="cspG"
                     /locus_tag="IRB70_000864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspG"
                     /protein_id="HBC0630812.1"
                     /translation="MSNKMTGLVKWFNADKGFGFITPDDGSKDVFVHFTAIQSNEFRT
                     LNENQKVEFSIEQGQRGPAAANVVTL"
     gene            44819..45007
                     /locus_tag="IRB70_000865"
     CDS             44819..45007
                     /locus_tag="IRB70_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBC0630813.1"
                     /translation="MTQHLHFRCPCCHGSQYRTSAFDVTERNPLGAKCIFCKSTMITF
                     DNVALQIRTEHAPLDFTK"
     gene            44982..45212
                     /gene="ymcE"
                     /locus_tag="IRB70_000866"
     CDS             44982..45212
                     /gene="ymcE"
                     /locus_tag="IRB70_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YmcE"
                     /protein_id="HBC0630814.1"
                     /translation="MRRWISQNNIRLPRGAFFISALFFFNAVCIVSDNLLIIESFGEM
                     AYNISYLTRVPGTNTLLACCCHLRPEEVNSEY"
     gene            45202..45375
                     /locus_tag="IRB70_000867"
     CDS             45202..45375
                     /locus_tag="IRB70_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HBC0630815.1"
                     /translation="MNIEELKKQAETEIADFIAQKIAELNKNTGKEVSEIRFTAREKM
                     TGLESYDVKIKIM"
     gene            complement(45424..46497)
                     /locus_tag="IRB70_000868"
     CDS             complement(45424..46497)
                     /locus_tag="IRB70_000868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBC0630816.1"
                     /translation="MAEKKRTRWQRRPGTTGGKLPWNDWRNATTWRKATQLLLLAMNI
                     YIAITFWYWVRYYETAGSTTFVARPGGIEGWLPIAGLMNLKYSLATGQLPSVHAAAML
                     LLVAFIVISLLLKKAFCSWLCPVGTLSELIGDLGNKLFGRQCVLPRWLDIPLRGVKYL
                     LLSFFLYIALLMPAQAIHYFMLSPYSVVMDVKMLDFFRHMGTATLISVTVLLIASLFI
                     RHAWCRYLCPYGALMGMVSLLSPFKIRRNAESCIDCGKCAKNCPSRIPVDKLIQVRTV
                     ECTGCMTCVESCPVASTLTFSLQKPAANKKAFALSGWLMTLLVLGIMFAVIGYAMYAG
                     VWQSPVPQELYRRLIPQAPMIGH"
     gene            complement(46580..49312)
                     /gene="torS"
                     /locus_tag="IRB70_000869"
     CDS             complement(46580..49312)
                     /gene="torS"
                     /locus_tag="IRB70_000869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001054736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system sensor histidine
                     kinase/response regulator TorS"
                     /protein_id="HBC0630817.1"
                     /translation="MNLTLTRRLWMGFALMALLTLTSTLVGWYNLRFISQVEKDNTQA
                     LIPTMNMARQLSEASAWELFAAQNLTSADNEKMWQAQGRMLTAQSLKINALLQALREQ
                     GFDTTAIEQQEQEISRSLRQQGELVGQRLQLRQQQQRLSQQIVAAADEIARLAQGQAN
                     NAATSAGATQAGIYDLIEQHQRQAAESALDRLIDIDLEYVNQMNELRLSALRVQQMVM
                     NLGLEQIQKNAATLEHQLNNAVKILQRRQIRIEDPGVRAQVATTLTTVSQYSDLLALY
                     QQDSEISNRLQTLAQNNIAQFAQFSSEVSQLVDTIELRNQHGLAHLEKASARGQYSLL
                     LLGMVSLCALILILWRVVYRSVTRPLAEQTQALQRLLDGDINSPFPETAGVRELDTIG
                     RLMDAFRSSVHALNRHREQLAAQVKARTAELQELVIEHRQARAEAEKASQAKSAFLAA
                     MSHEIRTPLYGILGTAQLLADNPALNAQRDDLRAITDSGESLLTILNDILDYSAIEAG
                     GKNVSVSDEPFEPRPLLESTLQLMSGRVKGRPIHLATAIADDVPTALMGDPRRIRQVI
                     TNLLSNALRFTDEGQIVLRSRTDGEQWLVEVEDSGCGIDPAKLAEIFQPFVQVSGKRG
                     GTGLGLTISSRLAQAMGGELSATSTPEVGSCFCLRLPLRVATAPVPKTVNQAVRLDGL
                     RLLLIEDNPLTQRITVEMLTTSGAQVVAVGNAAHAIETLQNSEPFAAALVDFDLPDID
                     GITLARQLAQQYPSLVLIGFSAHVIDETLRQRTSSLFRGIIPKPVPREVLGQLLAHYL
                     QLQVNNDQPLDVSQLNEDAQLMGTEKIHEWLILFKQHALPLLDEIDIARASQNSEKIK
                     RAAHQLKSSCSSLGMRSASQLCAQLEQQPLSAPLPHEEITRSVAALEAWLIRKT"
     gene            49395..50423
                     /gene="torT"
                     /locus_tag="IRB70_000870"
     CDS             49395..50423
                     /gene="torT"
                     /locus_tag="IRB70_000870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TMAO reductase system periplasmic protein TorT"
                     /protein_id="HBC0630818.1"
                     /translation="MRVLLLLLLSLFMLSAFSADNLLRWHDAQHFSVQPSTPLKTKRA
                     WKLCALYPSLKDSYWLSLNYGMQEAARRYGVDLKVLEAGGYSQLATQQAQIDQCKQWG
                     AEAILLGSSTTSFPDLQKQVASLPVIELVNAIDAPQVKSRVGVPWFQMGYQPGRYLVQ
                     WAHGKPLNVLLMPGPDNAGGSKEMVEGFRAAIAGSPVRIVDIALGDNDIEIQRNLLQE
                     MLERHPEIDVVAGTAIAAEAAMGEGRNLKTPLTVVSFYLSHQVYRGLKRGRVIMAASD
                     QMVWQGELAVEQAIRQLQGQSVSDNVSPPILVLTPKNADREHIRRSLSPGGFRPVYYY
                     QHTSAAKK"
     gene            complement(50396..51088)
                     /gene="torR"
                     /locus_tag="IRB70_000871"
     CDS             complement(50396..51088)
                     /gene="torR"
                     /locus_tag="IRB70_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator TorR"
                     /protein_id="HBC0630819.1"
                     /translation="MPHHIVIVEDEPVTQARLQSYFTQEGYTVSVTASGAGLREIMQN
                     QSVDLILLDINLPDENGLMLTRALRERSTVGIILVTGRSDRIDRIVGLEMGADDYVTK
                     PLELRELVVRVKNLLWRIDLARQAQPHTQDNCYRFAGYCLNVSRHTLERDGEPIKLTR
                     AEYEMLVAFVTNPGEILSRERLLRMLSARRVENPDLRTVDVLIRRLRHKLSADLLVTQ
                     HGEGYFLAADVC"
     gene            51218..52390
                     /gene="torC"
                     /locus_tag="IRB70_000872"
     CDS             51218..52390
                     /gene="torC"
                     /locus_tag="IRB70_000872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentaheme c-type cytochrome TorC"
                     /protein_id="HBC0630820.1"
                     /translation="MRKLWNALRRPSARWSVLALVATGIVIGIALIVLPHVGIKVTST
                     TEFCVSCHSMQPVYEEYKQSVHFQNASGVRAECHDCHIPPDIPGMVKRKLEASNDIYQ
                     TFIAHSIDTPEKFEAKRAELAEREWARMKENNSATCRSCHNYDAMDHAKQHPEAARQM
                     KVAAKDNQSCIDCHKGIAHQLPDMSSGFRKQFDELRASANDSGDTLYSIDIKPIYAAK
                     GDKEASGSLLPASAVKVIKRDGDWLQIEITGWTESAGRQRVLTQFPGKRIFVASIRGD
                     VQQQVKTLEKTTVADTNTEWSKLQATAWMKKGDMVNDIKPIWAYADSLYNGTCNQCHG
                     APEISHFDANGWIGTLNGMIGFTSLDKREERTLLKYLQMNASDTAGKAHGDKKEEK"
     gene            52390..54936
                     /gene="torA"
                     /locus_tag="IRB70_000873"
     CDS             52390..54936
                     /gene="torA"
                     /locus_tag="IRB70_000873"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine-N-oxide reductase TorA"
                     /protein_id="HBC0630821.1"
                     /translation="MNNNDLFQASRRRFLAQLGGLTVAGMLGPSLLTPRRATAAQAAT
                     EAVISKEGILTGSHWGAIRATVKDGRFVAAKPFELDKYPSKMIAGLPDHVHNAARIRY
                     PMVRVDWLRKRHLSDTSQRGDNRFVRVSWDEALDMFYEELERVQKTHGPSALLTASGW
                     QSTGMFHNASGMLAKAIALHGNSVGTGGDYSTGAAQVILPRVVGSMEVYEQQTSWPLV
                     LQNSKTIVLWGSDLLKNQQANWWCPDHDVYEYYEQLKAKVAAGEIEVISIDPVVTSTH
                     EYLGREHVKHIAVNPQTDVPLQLALAYTLYSENLYDKNFLANYCVGFEQFLPYLLGEK
                     DGQPKDAAWAEKLTGIDAETIRGMARQMAANRTQIIAGWCVQRMQHGEQWAWMIVVLA
                     AMLGQIGLPGGGFGFSWHYNGAGTPGRKGVILSGFSGSTSTPPVHDNSDYKGYSSTIP
                     IARFIDAILEPGKVINWNGKSVKLPPLKMCIFAGTNPFHRHQQINRIIEGWRKLETVI
                     AIDNQWTSTCRFADIVLPATTQFERNDLDQYGNHSNRGIIAMKQVVPPQFEARNDFDI
                     FRELCRRFNREEAFTEGLDEMGWLKRIWQEGVQQGKGRGVHLPAFDDFWNNKEYVEFD
                     HPQMFVRHQAFREDPDLEPLGTPSGLIEIYSKTIADMNYDDCQGHPMWFEKIERSHGG
                     PGSQKYPLHLQSVHPDFRLHSQLCESETLRQQYTVAGKEPVFINPQDASARGIRNGDV
                     VRVFNARGQVLAGAVVSDRYAPGVARIHEGAWYDPDKGGEPGALCKYGNPNVLTIDIG
                     TSQLAQATSAHTTLVEIEKYSGTVEQVTAFNGPVEMVAQCEYVPASQVKS"
     gene            54933..55532
                     /gene="torD"
                     /locus_tag="IRB70_000874"
     CDS             54933..55532
                     /gene="torD"
                     /locus_tag="IRB70_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone TorD"
                     /protein_id="HBC0630822.1"
                     /translation="MTTLTAPQIACVYAWLAQLFSRELDDEQLTQIASAQMAEWFSLL
                     KSEPPLTAAVNELENRIAALTVRDDARLELAADFCGLFLMTDKQAALPYASAYKQDEQ
                     EIKRLLVEAGMETSGNFNEPADHLAIYLELLSHLHFSLGEGSVPARRIDSLRQKTLTA
                     LWEWLPEFAARCRQYDSFGFYAALSQLLLVLVECDHQNR"
     gene            complement(55684..55989)
                     /gene="cbpM"
                     /locus_tag="IRB70_000875"
     CDS             complement(55684..55989)
                     /gene="cbpM"
                     /locus_tag="IRB70_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone modulator CbpM"
                     /protein_id="HBC0630823.1"
                     /translation="MANVTVTFTITEFCLHTGISEEELNEIVGLGVVEPREIQETTWV
                     FDDHAAIVVQRAVRLRHELALDWPGIAVALTLMDDIAHLKQENRLLRQRLSRFVAHP"
     gene            complement(55989..56909)
                     /gene="cbpA"
                     /locus_tag="IRB70_000876"
     CDS             complement(55989..56909)
                     /gene="cbpA"
                     /locus_tag="IRB70_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curved DNA-binding protein"
                     /protein_id="HBC0630824.1"
                     /translation="MELKDYYAIMGVKPTDDLKTIKTAYRRLARKYHPDVSKEPDAEA
                     RFKEVAEAWEVLSDEQRRAEYDQMWQHRNDPQFSRQFQHGDSQSFNAEDFDDIFSSIF
                     GQHARQSRQRPATRGHDIEIEVAVFLEETLTEHKRTISYNLPVYNAFGMIEQEIPKTL
                     NVKIPAGVGNGQRIRLKGQGTPGENGGPNGDLWLVIHIAPHPLFDIVGQDLEIVVPVS
                     PWEAALGAKVTVPTLKESILLTIPPGSQAGQRLRVKGKGLVSKKQTGDLYAVLKIVMP
                     PKPDENTAALWQQLADAQSSFDPRKDWGKA"
     gene            57169..58425
                     /locus_tag="IRB70_000877"
     CDS             57169..58425
                     /locus_tag="IRB70_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccE family protein"
                     /protein_id="HBC0630825.1"
                     /translation="MGSNIHGISCTANNYLKQAWHNIKKEHEKNQTYSITLFENTLVC
                     FMRLYKEIRRQKAEDYIPCLECESLEKEFEEMQNDNDLSLFMRTLRTNGTEIYSGVSG
                     GITYTIQYVRDIDIVRVSLPGRASESITDFKGYYWYGFMEYIENINACDDVFSECCLE
                     DENISVQPKQIHTPGISNLDAGINLSGISFIQSEINKTYELKYAPVDGDGYCLLRAIL
                     VLKQHDYSWALGSHKTQKEVYEEFIKIVDKPTIEALVDAAFCDLREDVKTLFGVDLQS
                     DNKIQGVGSHMSWSFLFFKKQFIDSCLNNEKCILHLPEFIFKDNKKLLALDTDASDRI
                     KAVKNFLAVLSDSICSSFIVTSNVASISLGNESFSTDEDLECGYLMNTGNHYDVYLPP
                     ELFAQAYKLNNKERNAQLDYLNRYVI"
     gene            58718..59959
                     /gene="agp"
                     /locus_tag="IRB70_000878"
     CDS             58718..59959
                     /gene="agp"
                     /locus_tag="IRB70_000878"
                     /EC_number="3.1.3.10"
                     /EC_number="3.1.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glucose-1-phosphatase/inositol
                     phosphatase"
                     /protein_id="HBC0630826.1"
                     /translation="MNKTLIAATVAGIVLLASNAQAQTVPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNKWPEWDVPGGQLTTKGGVLEVYMGHYMREWLAEQGMVKSGECP
                     PPDTVYAYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SEQAVAAMEKELSKLQLTDSYQLLEKIVNYKDSPACKEKQQCSLVDGKNTFSAKYQQE
                     PGVSGPLKVGNSLVDAFTLQYYEGFPMDQVAWGEIKSDQQWKVLSKLKNGYQDSLFTS
                     PEVARNVAKPLVSYIDKALVTDRTSAPKITVLVGHDSNIASLLTALDFKPYQLHDQNE
                     RTPIGGKIVFQRWHDSKTNRDLMKIEYVYQSAEQLRNADALTLQAPAQRVTLELSGCP
                     IDTNGFCPMDKFDSVLNEAVK"
     gene            complement(59997..60224)
                     /locus_tag="IRB70_000879"
     CDS             complement(59997..60224)
                     /locus_tag="IRB70_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002898701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccJ family protein"
                     /protein_id="HBC0630827.1"
                     /translation="MPTQEAKAHHVGEWASLRNTSPEIAEAIFEVAGYDEKMAEKIWE
                     EGSDEVLVKAFAKTDKDSLFWGEQTIERKNV"
     gene            complement(60245..60841)
                     /gene="wrbA"
                     /locus_tag="IRB70_000880"
     CDS             complement(60245..60841)
                     /gene="wrbA"
                     /locus_tag="IRB70_000880"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HBC0630828.1"
                     /translation="MAKVLVLYYSMYGHIETMARAVAEGANKVDGAEVVVKRVPETMP
                     PQLFEKAGGKTQTAPVATPQELADYDAIIFGTPTRFGNMSGQMRTFLDQTGGLWASGA
                     LYGKLASVFSSTGTGGGQEQTITSTWTTLAHHGMVIVPIGYAAQELFDVSQVRGGTPY
                     GATTIAGGDGSRQPSQEELSIARYQGEYVAGLAVKLNG"
     gene            61214..61387
                     /locus_tag="IRB70_000881"
     CDS             61214..61387
                     /locus_tag="IRB70_000881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415525.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HBC0630829.1"
                     /translation="MANHRGGSGNFAEDRERASEAGKKGGQHSGGNFKNDPQRASEAG
                     KKGGKSSHGKSDN"
     gene            complement(61470..62798)
                     /gene="rutG"
                     /locus_tag="IRB70_000882"
     CDS             complement(61470..62798)
                     /gene="rutG"
                     /locus_tag="IRB70_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization transport protein G"
                     /protein_id="HBC0630830.1"
                     /translation="MAMFGFPHWQLKSTSTESGVVAPDERLPFAQTAVMGVQHAVAMF
                     GATVLMPILMGLDPNLSILMSGIGTLLFFFITGGRVPSYLGSSAAFVGVVIAATGFNG
                     QGINPNISIALGGIIACGLVYTVIGLVVMKIGTRWIERLMPPVVTGAVVMAIGLNLAP
                     IAVKSVSASAFDSWMAVMTVLCIGLVAVFTRGMIQRLLILVGLIVACLLYGVMTNVLG
                     LGKAVDFTLVSHAAWFGLPHFSTPAFNGQAMMLIAPVAVILVAENLGHLKAVAGMTGR
                     NMDPYMGRAFVGDGLATMLSGSVGGSGVTTYAENIGVMAVTKVYSTLVFVAAAVIAML
                     LGFSPKFGALIHTIPAAVIGGASIVVFGLIAVAGARIWVQNRVDLSQNGNLIMVAVTL
                     VLGAGDFALTLGGFTLGGIGTATFGAILLNALLSRRLVDVPPPEVIHQEP"
     gene            complement(62819..63313)
                     /gene="rutF"
                     /locus_tag="IRB70_000883"
     CDS             complement(62819..63313)
                     /gene="rutF"
                     /locus_tag="IRB70_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309280.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization flavin reductase protein
                     F"
                     /protein_id="HBC0630831.1"
                     /translation="MNIVDQQTFRDAMSCMGAAVNIITTDGPAGRAGFTASAVCSVTD
                     TPPTLLVCLNRGASVWSVFNENRTLCVNTLSAGQELLSNLFGGKTPMEHRFAAARWQT
                     GVTGCPQLEEALVSFDCRISQVVSVGTHDILFCAIEAIHRHATPYGLVWFDRSYHALM
                     RPAC"
     gene            complement(63324..63914)
                     /locus_tag="IRB70_000884"
     CDS             complement(63324..63914)
                     /locus_tag="IRB70_000884"
                     /EC_number="1.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonic semialdehyde reductase"
                     /protein_id="HBC0630832.1"
                     /translation="MNEAVSPGALSTLFTDARTHNGWRETPVSDETLREIYALMKWGP
                     TSANCSPARIVFIRTPEGKERLRPALSSGNLQKTLTAPVTAIVAWDSEFYERLPQLFP
                     HGDARSWFTSSPQLAEETAFRNSSMQAAYLIVACRALGLDTGPMSGFDRQYVDDAFFA
                     GSTLKSNLLINIGYGDSSKLFARLPRLSFEEACGLL"
     gene            complement(63924..64724)
                     /gene="rutD"
                     /locus_tag="IRB70_000885"
     CDS             complement(63924..64724)
                     /gene="rutD"
                     /locus_tag="IRB70_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein D"
                     /protein_id="HBC0630833.1"
                     /translation="MKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLEQEYQVVC
                     YDQRGTGNNPDTLAEDYSIAQMAAELHQALVAAGIERYAVVGHALGALVGMQLALDYP
                     ASVTVLVSVNGWLRINAHTRRCFQVREQLLHSGGAQAWVAAQPLFLYPADWMAARAPR
                     LEAEDALALAHFQGKNNLLRRLNALKRADFSHHADRIRCPVQIICASDDLLVPTACSS
                     ELHAALPDSQKMVMRYGGHACNVTDPETFNALLLNGLASLLHHREAAL"
     gene            complement(64732..65118)
                     /gene="rutC"
                     /locus_tag="IRB70_000886"
     CDS             complement(64732..65118)
                     /gene="rutC"
                     /locus_tag="IRB70_000886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein C"
                     /protein_id="HBC0630834.1"
                     /translation="MPKSVIIPAGSSAPLAPFVPGTLADGVVYVSGTLAFDQHNNVLF
                     ADDPKAQTRHVLENIRKVIETAGGSMADVTFNSIFITDWKNYAAINEIYAEFFPGDKP
                     ARFCIQCGLVKPDALVEIATIAHIAK"
     gene            complement(65130..65822)
                     /gene="rutB"
                     /locus_tag="IRB70_000887"
     CDS             complement(65130..65822)
                     /gene="rutB"
                     /locus_tag="IRB70_000887"
                     /EC_number="3.5.1.110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415531.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxyureidoacrylate/ureidoacrylate
                     amidohydrolase RutB"
                     /protein_id="HBC0630835.1"
                     /translation="MTTLTARPEAITFDPQQTALIVVDMQNAYATPGGYLDLAGFDVS
                     TTRPVIANIQTAVTAARAAGMLIIWFQNGWDAQYVEAGGPGSPNFHKSNALKTMRKQP
                     QLQGKLLAKGSWDYQLVDELVPQPGDIVLPKPRYSGFFNTPLDSILRSRGIRHLVFTG
                     IATNVCVESTLRDGFFLEYFGVVLEDATHQAGPEFAQKAALFNIETFFGWVSDVETFC
                     DALSPTSFARIA"
     gene            complement(65822..66913)
                     /gene="rutA"
                     /locus_tag="IRB70_000888"
     CDS             complement(65822..66913)
                     /gene="rutA"
                     /locus_tag="IRB70_000888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309285.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine utilization protein A"
                     /protein_id="HBC0630836.1"
                     /translation="MKIGVFVPIGNNGWLISTHAPQYMPTFELNKAIVQKAEHYHFDF
                     ALSMIKLRGFGGKTEFWDHNLESFTLMAGLAAVTSRIQIYATAATLTLPPAIVARMAA
                     TIDSISGGRFGVNLVTGWQKPEYEQMGIWPSDDYFSRRYDYLTEYVQVLRDLWGTGKS
                     DFKGDFFTMNDCRVSPQPSVPMKVICAGQSDAGMAFSAQYADFNFCFGKGVNTPTAFA
                     PTAARMKQAAEQTGRDVGSYVLFMVIADETDDAARAKWEHYKAGADEEALSWLTEQSQ
                     KDTRSGTDTNVRQMADPTSAVNINMGTLVGSYASVARMLDEVATVPGAEGVLLTFDDF
                     LSGIENFGERIQPLMQCRAHLPALTQEVA"
     gene            67201..67839
                     /gene="rutR"
                     /locus_tag="IRB70_000889"
     CDS             67201..67839
                     /gene="rutR"
                     /locus_tag="IRB70_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator RutR"
                     /protein_id="HBC0630837.1"
                     /translation="MTQGAVKITGKRSRAVSAKKKAILSAALDTFSQFGFHGTRLEQI
                     AELAGVSKTNLLYYFPSKEALYIAVLRQILDIWLAPLKAFREDFAPLAAIKEYIRLKL
                     EVSRDYPQASRLFCMEMLAGAPLLMDELTGDLKALIDEKSALIAGWVKSGKLAPIDPQ
                     HLIFMIWASTQHYADFAPQVEAVTGATLRDEVFFNQTVENVQRIIIEGIRPR"
     gene            complement(67879..71841)
                     /gene="putA"
                     /locus_tag="IRB70_000890"
     CDS             complement(67879..71841)
                     /gene="putA"
                     /locus_tag="IRB70_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trifunctional transcriptional regulator/proline
                     dehydrogenase/L-glutamate gamma-semialdehyde
                     dehydrogenase"
                     /protein_id="HBC0630838.1"
                     /translation="MGTTTMGVKLDDATRERIKSAATRIDRTPHWLIKQAIFSYLEQL
                     ENSDTLPELPALLSGAANESDEAPTPAEEPHQPFLDFAEQILPQSVSRAAITAAYRRP
                     ETEAVSMLLEQARLPQPVAEQAHKLAYQLADKLRNQKNASGRAGMVQGLLQEFSLSSQ
                     EGVALMCLAEALLRIPDKATRDALIRDKISNGNWQSHIGRSPSLFVNAATWGLLFTGK
                     LVSTHNEASLSRSLNRIIGKSGEPLIRKGVDMAMRLMGEQFVTGETIAEALANARKLE
                     EKGFRYSYDMLGEAALTAADAQAYMVSYQQAIHAIGKASNGRGIYEGPGISIKLSALH
                     PRYSRAQYDRVMEELYPRLKSLTLLARQYDIGINIDAEEADRLEISLDLLEKLCFEPE
                     LAGWNGIGFVIQAYQKRCPLVIDYLIDLATRSRRRLMIRLVKGAYWDSEIKRAQMDGL
                     EGYPVYTRKVYTDVSYLACAKKLLAVPNLIYPQFATHNAHTLAAIYQLAGQNYYPGQY
                     EFQCLHGMGEPLYEQVTGKVADGKLNRPCRIYAPVGTHETLLAYLVRRLLENGANTSF
                     VNRIADTSLPLDELVADPVTAVEKLAQQEGQTGLPHPKIPLPRDLYGHGRDNSAGLDL
                     ANEHRLASLSSALLNSALQKWQSLPMLEQPVAAGEMSPVINPAEPKDIVGYVREATPR
                     EVEQALESAVNNAPIWFATPPAERAAILHRAAVLMESQMQQLIGILVREAGKTFSNAI
                     AEVREAVDFLHYYAGQVRDDFANETHRPLGPVVCISPWNFPLAIFTGQIAAALAAGNS
                     VLAKPAEQTPLIAAQGIAILLEAGVPPGVVQLLPGRGETVGAQLTGDDRVRGVMFTGS
                     TEVATLLQRNIASRLDAQGRPIPLIAETGGMNAMIVDSSALTEQVVIDVLASAFDSAG
                     QRCSALRVLCLQDEIADHTLKMLRGAMAECRMGNPGRLTTDIGPVIDSEAKANIERHI
                     QTMRSKGRQVFQPVRENSEDTREWQSGTFVAPTLIELDDFAELQKEVFGPVLHVVRYN
                     RNQLPALIEQINASGYGLTLGVHTRIDETIAQVTGSAHVGNLYVNRNMVGAVVGVQPF
                     GGEGLSGTGPKAGGPLYLYRLLANRPESALAVTLARQDAEYPVDAQLKAALTQPLNAL
                     REWAANRPELQALCTQYGELAQAGTQRLLPGPTGERNTWTLLPRERVLCIADDEQDAL
                     TQLAAVLAVGSQVLWPDDTLHHQLVKALPSAVSERIQLAKAENITAQPFDAVIFHGDS
                     DQLRALCEAVAARDGAIVSVQGFARGESNILLERLYIERSLSVNTAAAGGNASLMTIG
                     "
     gene            71896..72105
                     /locus_tag="IRB70_000891"
     CDS             71896..72105
                     /locus_tag="IRB70_000891"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630839.1"
                     /translation="MMLQLCATMLNVTCVASLKMNEMLIKEIDMTGIKKITQTFSLRQ
                     LTFLKGATAKNVRECNLMKNSVAEH"
     gene            72264..73772
                     /gene="putP"
                     /locus_tag="IRB70_000892"
     CDS             72264..73772
                     /gene="putP"
                     /locus_tag="IRB70_000892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/proline symporter PutP"
                     /protein_id="HBC0630840.1"
                     /translation="MAISTPMLVTFCVYIFGMILIGFIAWRSTKNFDDYILGGRSLGP
                     FVTALSAGASDMSGWLLMGLPGAVFLSGISESWIAIGLTLGAWINWKLVAGRLRVHTE
                     YNNNALTLPDYFTGRFEDKSRILRIISALVILLFFTIYCASGIVAGARLFESTFGMSY
                     ETALWAGAAATILYTFIGGFLAVSWTDTVQASLMIFALILTPVIVIISVGGFGDSLEV
                     IKQKSIENVDMLKGLNFVAIISLMGWGLGYFGQPHILARFMAADSHHSIVHARRISMT
                     WMILCLAGAVAVGFFGIAYFNEHPAVAGAVNQNAERVFIELAQILFNPWIAGILLSAI
                     LAAVMSTLSCQLLVCSSAITEDLYKAFLRKHASQKELVWVGRVMVLVVALVAIALAAN
                     PENRVLGLVSYAWAGFGAAFGPVVLFSVMWSRMTRNGALAGMIIGALTVIVWKQFGWL
                     GLYEIIPGFIFGSIGIVVFSLLGKAPSAAMQKRFAEADAHYHSAPPSRLQEG"
     gene            73992..74822
                     /locus_tag="IRB70_000893"
     CDS             73992..74822
                     /locus_tag="IRB70_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family protein"
                     /protein_id="HBC0630841.1"
                     /translation="MFVPFLIMLREGLEAALIVSLIASYLKRTQRGRWIGVMWIGVLL
                     AAALCLGLGIFINETTGEFPQKEQELFEGIVAVIAVVILTWMVFWMRKVSRNVKVQLE
                     QAVDSALQRGNHHGWALVMMVFFAVAREGLESVFFLLAAFQQDVGIWPPLGAMLGLAT
                     AVVLGFLLYWGGIRLNLGAFFKWTSLFILFVAAGLAAGAIRAFHEAGLWNHFQEIAFD
                     MSAVLSTHSLFGTLMEGIFGYQEAPSVSEVAVWFIYLIPALVAFALPPRAGATASRSA
                     "
     gene            74880..76007
                     /gene="efeO"
                     /locus_tag="IRB70_000894"
     CDS             74880..76007
                     /gene="efeO"
                     /locus_tag="IRB70_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron uptake system protein EfeO"
                     /protein_id="HBC0630842.1"
                     /translation="MTINFRRNALQLSVAALFSSAFMANAADIPQVKVTVTDKQCEPM
                     TITVNAGKTQFIIQNHSQKALEWEILKGVMVVEERENIAPGFSQKMTANLQPGEYDMT
                     CGLLTNPKGKLIVKGEATADAAQSDALLSLGGAITAYKAYVMAETTQLVTDTKAFTDA
                     IKAGDIEKAKALYAPTRQHYERIEPIAELFSDLDGSIDAREDDYEQKAADPKFTGFHR
                     LEKALFGDNTTKGMDKYADQLYTDVVDLQKRISELAFPPSKVVGGAAGLIEEVAASKI
                     SGEEDRYSHTDLWDFQANVEGSQKIVDLLRPQLQKANPELLAKVDANFKKVDTILAKY
                     RTKDGYETYDKLTDADRNALKGPITALAEDLAQFRGVLGLD"
     gene            76013..77284
                     /gene="efeB"
                     /locus_tag="IRB70_000895"
     CDS             76013..77284
                     /gene="efeB"
                     /locus_tag="IRB70_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deferrochelatase/peroxidase EfeB"
                     /protein_id="HBC0630843.1"
                     /translation="MQYEDENGVNEPSRRRLLKGIGALALAGSCPVAHAQKTQSAPGT
                     LSPDARSEAQPFYGEHQAGILTPQQAAMMLVAFDVLASDKTDLERLFRLLTQRFAFLT
                     QGGAAPETPNPRLPPLDSGILGGYIAPDNLTITLSVGHSLFDERFGLAPQMPKKLQKM
                     TRFPNDSLDAALCHGDVLLQICANTQDTVIHALRDIIKHTPDLLSVRWKREGFISDHA
                     ARSKGKETPINLLGFKDGTANPDSQNAKLMQKVVWVTADQQEPAWTIGGSYQAVRLIQ
                     FRVEFWDRTPLKEQQTIFGRDKQTGAPLGMQHEHDVPDYASDPEGKVIALDSHIRLAN
                     PRTPESESSLMLRRGYSYSLGVTNSGQLDMGLLFVCYQHDLEKGFLTVQKRLNGEALE
                     EYVKPIGGGYFFALPGVKDANDYLGSALLRV"
     gene            77892..78680
                     /gene="phoH"
                     /locus_tag="IRB70_000896"
     CDS             77892..78680
                     /gene="phoH"
                     /locus_tag="IRB70_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate starvation-inducible protein PhoH"
                     /protein_id="HBC0630844.1"
                     /translation="MGRQKAVIKARREAKRVLRRDSRSHKQREEESVTSLVQMSGVEA
                     IGMARDSRDTSPILARNEAQLHYLKAIESKQLIFATGEAGCGKTWISAAKAAEALIHK
                     DVDRIIVTRPVLQADEDLGFLPGDIAEKFAPYFRPVYDVLVRRLGASFMQYCLRPEIG
                     KVEIAPFAYMRGRTFENAVVILDEAQNVTAAQMKMFLTRLGENVTVIVNGDITQCDLP
                     RGVCSGLSDALERFEEDEMVGIVRFGKEDCVRSALCQRTLHAYS"
     gene            complement(78730..79143)
                     /gene="pgaD"
                     /locus_tag="IRB70_000897"
     CDS             complement(78730..79143)
                     /gene="pgaD"
                     /locus_tag="IRB70_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001061089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     biosynthesis protein PgaD"
                     /protein_id="HBC0630845.1"
                     /translation="MNNLIITTRQSPVRLLVDYVATTILWTLFALFIFLFAIDLLTGY
                     YWQSEARSRLQFYFLLAVANAVVLIVWALYNKLRFKKQQHHAAYQYTPREYAESLAIP
                     DELYQQLQKSHRMSVHFTSQGQIKMVVSEKTLVRV"
     gene            complement(79145..80470)
                     /gene="pgaC"
                     /locus_tag="IRB70_000898"
     CDS             complement(79145..80470)
                     /gene="pgaC"
                     /locus_tag="IRB70_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine synthase"
                     /protein_id="HBC0630846.1"
                     /translation="MINRIVSFFILCLVLCIPLCVAYFHSGELMMRFVFFWPFFMSIM
                     WIVGGVYFWVYRERHWPWGENAPAPQLKDNPSISIIIPCFNEEKNVEETIHAALAQRY
                     ENIEVIAVNDGSTDKTRAILDRMAAQIPHLRVIHLAQNQGKAIALKTGAAAAKSEYLV
                     CIDGDALLDRDAAAYIVEPMLYNPRVGAVTGNPRIRTRSTLVGKIQVGEYSSIIGLIK
                     RTQRIYGNVFTVSGVIAAFRRSALAEVGYWSDDMITEDIDISWKLQLNQWTIFYEPRA
                     LCWILMPETLKGLWKQRLRWAQGGAEVFLKNMTRLWRKENFRMWPLFFEYCLTTIWAF
                     TCLVGFIIYAVQLAGVPLNIELTHIAATHTAGILLCTLCLLQFIVSLVIENRYEHNLA
                     SSLFWIIWFPVIFWMLSLATTLVSFTRVMLMPKKQRARWVSPDRGILRG"
     gene            complement(80463..82481)
                     /gene="pgaB"
                     /locus_tag="IRB70_000899"
     CDS             complement(80463..82481)
                     /gene="pgaB"
                     /locus_tag="IRB70_000899"
                     /EC_number="3.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6-N-acetyl-D-glucosamine
                     N-deacetylase PgaB"
                     /protein_id="HBC0630847.1"
                     /translation="MLRNGNKYILMLVSIIMLTACISQSRTSFIPPQDRESLLAEQPW
                     PHNGFVAISWHNVEDEAADQRFMSVRTSALREQFAWLRENGYQPVSIAQIREAHRGGK
                     PLPEKAVVLTFDDGYQSFYTRVFPILQAFQWPAVWAPVGSWVDTPADEQVKFGDEMVD
                     REYFATWQQVREVARSRLVEVASHTWNSHYGIQANATGSLLPVYVNRAYFTDHARYET
                     AAEYRERIRLDAVKMTEYLRTKAEVNPHVFVWPYGEANGIAIAELKKLGYDMFFTLES
                     GLANASQLDSIPRVLIANNPSLKEFAQQIITVQEKPLQRVMHIDLDYIYDENRQQMDR
                     NIDVLIQRVKDMQISTVYLQAFADPDGDGLVKEVWFPNRLLPMKADIFSRVAWQLRTR
                     SGVNIYAWMPVLSWDLDPTLTRVKYLPTGEKKAQIHPEQYRRLSPFDDRVRAQVGMLY
                     DDLAGHAAFDGILFHDDALLSDYEDASAPAIAAYQQAGFSGSLSEIRQNPEQFKQWTR
                     FKSRALTDFTLELSARVKAIRGPHVKTARNIFALPVIQPESEAWFAQNYADFLKSYDW
                     TAIMAMPYMEGVTEKLADQWLTQLTNQMKSIPQAKDKSILELQAQNWQKNGQHQAISS
                     QQLAHWMSLLQLNGVKNYGYYPDNFLHNQPEIDVIRPEFSTAWYPKND"
     gene            complement(82490..84913)
                     /gene="pgaA"
                     /locus_tag="IRB70_000900"
     CDS             complement(82490..84913)
                     /gene="pgaA"
                     /locus_tag="IRB70_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="poly-beta-1,6 N-acetyl-D-glucosamine export
                     porin PgaA"
                     /protein_id="HBC0630848.1"
                     /translation="MYSSSRKRCPKTKWALKILTAAFLAASPAAKSAVNNAYDALIIE
                     ARKGNTQPALLWFAQKSALSNNQIADWLQIALWAGQDKQVITVYNRYRHQQLPARGYA
                     AVAVAYRNLQQWQNSLTLWQKALSLESQNKDYQRGQILTLADAGHYDSALVKLKQLNS
                     GAPDKANLLAEAYIYKLAGRHEDELRAMTGSLPENALTQQYPTEYVQALRNNQLTAAI
                     DDANLTPDIRADIHAELVRLSFMPTRSESERYAIADRALAQYAALEILWYDNPDRTAQ
                     YQRIQVDHLGALLTRDRYKDVISHYQRLKKTGQIIPPWAQYWVASAYLKEHQPKKAQS
                     IMTELFYHKETIAPDLSDEELADLFYSHLESENYPGALTVTQHTINTSPPFLRLMGTP
                     TSIPNDTWLQGHSFLSTVAKYSNDLPQAEMIARELAYNAPGNQGLRIDYASVLQARGW
                     PRAAENELKKAEVIEPRNINLEVEQAWTALTLQEWQQAAVLTHDVVEREPQDPGVVRL
                     KRAVDVHNLAELRIAGSTGIDAEGPDSGKHDVDLTTIVYSPPLKDNWRGFAGFGYADG
                     QFSEGKGIVRDWLAGVEWRSRNIWLEAEYAERVFNHEHKPGARLSGWYDFNDNWRIGS
                     QLERLSHRVPLRAMKNGVTGNSAQAYVRWYQNERRKYGVSWAFTDFSDSNQRQEVSLE
                     GQERIWSSPYLIVDFLPNLYYEQNTEHDTPYYNPIKTFDIVPAFEASHLLWRSYENSW
                     EQIFSAGVGASWQKHYGTDVVTQLGYGQRISWNDVIDAGATLRWEKRPYDGDREHNLY
                     VEFDMTFRF"
BASE COUNT        21155 a        20961 c        22315 g        20674 t
ORIGIN      
        1 ggatattcaa tagatgttga atcaatgaat tactcgttca ggtaataaag aaagattcat
       61 ggaatctata aataaaagat ttgtcacgta ttgagtaagc actactggtt taaatggcgg
      121 tcatttgttg ttattattaa gtccaatgtc atttgcaggc attatcatat ttacgaaaaa
      181 atcaggatga taacgatgaa aaaaaatgta ttggcggcgt ttataactgt gatatgtaca
      241 acttcaagtg ttatggcggc tgatgataat gccatcacgg acggctcggt tacgtttaat
      301 ggtaaagtca ttgctcctgc ctgtacgctg gttgctgcga cgaaagattc cgtggtgact
      361 ttaccagatg ttagtgccac gaagttgcaa agtaatggtc aggtttctgg ggtgcaaact
      421 gatgtgccaa ttgcattaga agattgtgat attaccgtaa caaaaaatgc aacgttcact
      481 tttaatggca cagcggatac tacgcagatt acagcgtttg ctaaccaggc ctcatctgag
      541 gctgctacaa acgtggccct gcaaatgtat atgaatgatg gtacaacggt cattacgcca
      601 gacacagaaa ccgggaatat tttgttgcag agtggaaatc aaacgctaac ttttaaagta
      661 gattatatcg ctacgggtaa agcgacgtca ggtaatgtta atgcggtaac aaatttccat
      721 attaactatt attaatagaa ctcattaatt gttttattaa ttagtacccc tccagtgttc
      781 tggaggggat attcatattt gttaagagtg actatttatg aaaacttgca taacaaaggg
      841 aattgtgacc gtaagtttaa cggcaatatt actcagctgt tcgttcacat gggcggcagg
      901 taaaggtggg gtcggacttg cagcaacacg tcttgtttat tcggaaggtg aagagcaaat
      961 ttcactgggt gtacgtaaca ccagtccgga tgttccttat cttattcagt catgggtgat
     1021 gacaccagat aataaaaagt cagcggactt tattattaca ccaccgctat ttgtgctgaa
     1081 tccagcaaac gagaacctgc tacgcattat gtacattggc gcgccgttgg cgaaagacag
     1141 agaaactctt ttcttcacca gcgtacgggc agtcccttca acaacgaagc gggaagaagg
     1201 caataccctg aagattgcca cacaaagcgt catcaaactt ttctggcgac caaaaggttt
     1261 agcgtatccc ttagccgagg ctccggcgaa actgcgttgc acttcgtcag ctgacatggt
     1321 tacggtcagt aacccaacac cttatttcat taccctgaca gacctgaaaa taggtggaaa
     1381 agtagttaaa aatcaaatga tttccccctt tgataaatac caattccctc tgccaaaggg
     1441 tgctcaaaac agtagcgtaa cgtaccgaac tatcaatgac tacggggcgg aaacgccgca
     1501 actcaactgt aaatcgtaag ccgtcttcag ttaagagagc gagatgccta gaactcaccg
     1561 acaacacagc ctgttaagct ctggtagagt gccatcgttt attggtgggc tggtggtgtt
     1621 tgtgtcggca gcgttcaatg cacaagctga aacctggttc gatccagcct ttttcaaaga
     1681 tgatccctca atggtggctg atttgtctcg tttcgaaaaa gggcaaaaaa taacgccagg
     1741 ggtttatcga gtcgatattg ttctgaatca gacaattgta gatacgcgca acgtcaattt
     1801 tgttgagata acgccagaga aggggattgc cgcctgtttg acgactgaaa gcctggatgc
     1861 aatgggcgtg aatactgatg cgtttccggc ttttaaacaa ctggataaac aagcgtgtgc
     1921 gccattggcg gaaattattc cggatgccag cgtaactttt aatgtgaata aactccgtct
     1981 ggaaatttca gtaccgcaaa tcgccatcaa aagtaacgct cgtggttatg tcccccctga
     2041 acgttgggat gaagggatca acgcgctatt actgggatat tcatttagcg gggctaacag
     2101 tattcatagc agcgcaggta gtgattctgg cgacagctat tttctgaatt taaacagtgg
     2161 cgttaattta ggcccatgga gattgcgcaa caattcaaca tggagtcgca gtagtggcca
     2221 aaccgcagaa tggaagaatc tcagcagcta tttgcagcgg gcggtgattc cattaaaagg
     2281 cgaactgacc gtcggtgatg attatacggc aggcgatttt tttgatagcg tcagctttcg
     2341 tggcgtgcag ctggcgtcag atgacaacat gctgccagac agcttgaaag ggtttgcgcc
     2401 agtggtgcgt ggtatcgcca aaagcaatgc acaggtaacg attaagcaaa atggttacac
     2461 catctatcaa acttatgttt cgcctggcgc ttttgagatt agtgatctct actctacgtc
     2521 gtcgagtggt gatttgttgg ttgaaatcaa agaagctgac ggtagtgtca atagttacag
     2581 tgtgcccttt tccagcgtgc cattactcca gcgtcaggga cgcatcaaat atgcggtgac
     2641 gctggcgaaa tacagaacca atagtaatga ccagcaagaa agtaaatttg ctcaggccac
     2701 gctgcaatgg ggcgggccgt ggggaacgac ctggtatggc ggagggcaat atgctgaata
     2761 ttaccgtgcc gctatgtttg gtctgggttt taacctcggc gatttcggag caatttcgtt
     2821 cgacgcgacc caggctaaaa gtacgctggc agaccaaagt gaacataaag ggcagtcata
     2881 tcgttttctg tatgccaaaa cgctcaacca attgggcacc aactttcaat tgatgggcta
     2941 ccgctattcg acgtcgggtt tctacaccct ttccgacact atgtataaac acatggatgg
     3001 ctacgaattt aatgacggtg atgatgaaga tacgccaatg tggtcgcgtt attacaattt
     3061 gttttacacc aaacgtggca aactgcaggt caacatctcc cagcaattag gcgagtacgg
     3121 ttcgttttat ttaagcggta gccagcaaac ttactggcat accgatcaac aggatcggct
     3181 attacagttt ggctacaaca cgcaaattaa agatctctcg ctgggggttt cctggaacta
     3241 cagtaagtcc cgtggtcaac ctgacgctga ccaggtgttt gcacttaatt tttccctgcc
     3301 gctcaatctg ttgctcccca aaagtaatga tagctatacc aggaaaaaaa attacgcctg
     3361 gatgacctct aataccagta tcgataacga agggcacact acacaaaacc tgggtttaac
     3421 ggagacacta ctcgatgacg gtaatctgag ctacagcgtg caacagggat ataacagcga
     3481 ggggaaaacg gctaatggta gcgccagcat ggactacaaa ggggcgtttg cagatgctcg
     3541 agtgggctac aactacagcg ataacggcag tcaacaacaa ctgaactacg ctctttcagg
     3601 cagtttagtt gcccattcgc agggtattac gttgggtcaa tcattgggtg aaactaatgt
     3661 cctgattgcc gcgccaggcg ccgaaaatac tcgtgtggcg aacagcaccg ggctgaaaac
     3721 tgactggcgt ggatataccg ttgtgcctta tgccacttct tatcgggaaa atcgaattgc
     3781 acttgatgcg gcgtcgttaa aacgtaacgt ggatcttgaa aatgccgtag taaacgtggt
     3841 tcccaccaaa ggggcattgg ttctggcgga gttcaatgcc catgcggggg ccagggtatt
     3901 aatgaaaaca tcaaagcagg gtatgccgct gagatttggt gcaatggcaa cactggatgg
     3961 cgcacaaaca attagcggta tcattgatga tgatggttcg ctctatatgt ctggtttgcc
     4021 ggcgaaggga acgataactg tacgctgggg cgacgctccc gatcaaattt gtcatatcag
     4081 ttacgagctt accgaacaac aaattaacgc tgcgattacg cggatggatt cagtatgcga
     4141 ataatttcag gggatagtag tgtgttaaga ctccggcttc ttttgactgc tgttttaatg
     4201 ctgtggggat ttcatgccgc cgcttatacc gggcagtgtc ataccactca ggggaatccg
     4261 tatattggcg tcaattttgg cgttaaaacc ctggaggagg aagagaatac ggctggaaaa
     4321 gtcaaagatg aattttatca gtggagtgaa tcgaatgatt attatgtttc ctgcgattgc
     4381 gataaagaca atgtcagaag tggtctatgg gcattcgctg cggattctcc gttagtttat
     4441 ttgggcgaca actggtacaa aattaacgat tatcttgccg caaaggtgct attaggagtg
     4501 aaaggtaaca caccttcggc cgtacctttt gaaaatctcg gtacaggaag tgatacccga
     4561 tggcatattt gcgatcccgg tggtcaacgt ttgggcggca agggggcaag cggcaatagc
     4621 ggaagttttt cactgaaaat attgcagccg tttgtcggtt cggtcgtcat tcctcctatg
     4681 gcgctggcgc gactatatga gtgttacaac atacccgcaa gtgattcctg cacgactaca
     4741 ggtacaccgg ttttagtgta ttacctgtct ggtacgatta attcacttgg ctcatgttct
     4801 gtcaattctg gagagacaat agaggttgat ttgggggatg tatttgctgc caatttccgt
     4861 gttgtagggc ataaaccgct tggatccaga acggcagaac tctcaattcc agtcaggtgt
     4921 aataccggaa acgcagagct ggttaatgtt aatttgagtc tgacggcaac cagtgatccc
     4981 gattatcctc aggcaatcaa gacatcacga ccaggtgtcg gtgttgtggt caccgacagc
     5041 caaaacaaca ttatttcgcc tgccggtggc acactgccgc tatccatccc tgacgacgcg
     5101 gacagcttcg ctcgaatgaa tgtttatccg gtcagcacga caggtgtacc accggaaacc
     5161 gggagctttg aagccacagc aacggtgaga ataaactttg actgatatgt gaacgtatga
     5221 aaaagaacac aatatttcaa gtcgttatct tatcattcac tttgctttat atgcatgtcg
     5281 ggatagctgg acctgaacaa gtcagtatgc atatttatgg taatgtggtc gatcagggct
     5341 gtgatgttgc caccaaaagt gcattacaaa atattcatat tggtgatttt aatatcagtg
     5401 attttcagac cgcgaatacc gtaagcactg ctgctgattt gaatatcgat atcaccggtt
     5461 gtgccgctgg tattactggc gcggacgtcc tttttagcgg cgaggctgac acccttgtgc
     5521 cgacactgct caaattaact gacacaggcg gaagcggtgg tatggcaacg gggattgctg
     5581 tgcaaattct tgatgcgcaa agtcagcaag aaatcccgct caatcaggtc ctacctctta
     5641 cgcccttaaa agccggggat aacacactca aatatcaact tcgttataag tccacaaagg
     5701 cgggagcaac gggcggtaat gcgacggcgg ttctctattt tgatctggtt taccagtgaa
     5761 ggagtgatgt tgaaacagat aatctggatt ctgttcttac tgggattaac ggggggctgt
     5821 gagctatttg cccatgatgg cacggtcaac attagcggat cgtttcgccg taatacatgc
     5881 gtgctggcac aggatagcaa gcaaatcaat gtgcagttag gcgacgtctc gctgacacgt
     5941 ttttctcatg ggaattatgg cccggagaaa tcgttcatca ttaatttgca ggattgcgga
     6001 acagatgtca gcacggttga cgtcaccttt tcaggaaccc ccgacggagt acagagcgaa
     6061 atgctgtcca ttgaaagtgg tacggatgca gccagtgggc tggcaattgc aattctggat
     6121 gatgcgaaga tattgattcc gcttaaccag gcgagtaaag actacagcct acatagcggt
     6181 aaggtgccat taacttttta cgcgcaattg cgacctgtca atagcgatgt gcagtcgggt
     6241 aaagtgaatg ccagcgcgac atttgtactt cattatgact aatacgtgga acagattggc
     6301 gctcttgatt ttcgccgttt tatcgctgct ggtggcgagt gaattgcagg caggagtggt
     6361 ggtcggcgga acgcgattta tctttccggc agacagagat tcgatatcta ttttattgac
     6421 taataccagt caggaatcct ggcttattaa cagtaaaatc aatcgcccaa cgcgttgggc
     6481 tggggatgaa gcgtcgacag taccagcacc attactggcc gctccgccac ttattctcct
     6541 gaagcccggt actacaggca cattgcgctt gctgagaacg gaaagcgaca tcttgcccgt
     6601 ggatcgcgaa acgctatttg agttaagcat tgccagcgtg ccatccggca aagttgaaaa
     6661 tcagagcgta aaagtggcga tgcgctcggt atttaaactg ttctggcgac ccgaaggttt
     6721 gccgggcgac ccgctggaag cttatcaaca attacgctgg acacggaatt cgcagggtgt
     6781 acaactcact aacccaacgc cttactacat taacctgatt caggtgagcg taaatggtaa
     6841 agcgttaagt aatgcgggag ttgtgccacc taaaagccag cgtcagacaa gctggtgtca
     6901 ggctataaca ccgtgtcacg tctcctggcg gacgataaat gattacggcg ggttgagtgc
     6961 aaagaaggag caaaatctgc cctgaaacag gctcggaaaa cgtttgcgct ttttttgcca
     7021 caggtcaatt cccttttggt ccgaactcgc acataatacg cccccggttt gcacaccggg
     7081 aatccaggag agttcatgta ctaccccttc gttcgtaaag cccttttcca gctcgatcca
     7141 gagcgcgctc atgagtttac ttttcagcaa ttacgccgta ttaccggaac gccgtttgaa
     7201 gcactggtgc ggcagaaagt gcctgcgaaa cctgttaact gcatgggcct gacgtttaaa
     7261 aatccgcttg gtctggcagc cggtcttgat aaagacgggg agtgcattga cgcgttaggc
     7321 gcgatgggat ttggatcgat cgagatcggt accgtcacgc cacgtcccca gccaggtaat
     7381 gacaagccgc gtctctttcg tctggtagat gccgaaggtt tgatcaaccg tatgggcttt
     7441 aataatcttg gcgttgataa cctcgtagag aacgtaaaaa aagcccatta tgacggcgtt
     7501 ctgggtatta acatcggcaa aaataaagat acgccggtgg agcagggtaa agatgactat
     7561 ctgatttgta tggaaaaaat ctatgcctat gcgggatata tcgccatcaa tatttcatcg
     7621 ccaaataccc caggattacg cacactgcaa tatggtgaag cgctggatga tctcttaacc
     7681 gcgattaaaa ataagcaaaa tgatttgcaa gagatgcacc ataaatatgt gccgatcgca
     7741 gtgaagatcg cgccggatct ttctgaagaa gaattgatcc aggttgccga tagtttagtt
     7801 cgccataata ttgatggcgt tattgcaacc aataccacgc tcgatcgttc tctggttcag
     7861 ggaatgaaaa attgtgatca aaccggtggc ttaagtggtc gtccgcttca gttaaaaagc
     7921 acagaaatta ttcgccgctt gtcacaggaa ttaaacggtc gcttaccgat catcggtgtt
     7981 ggcggcattg actcggttat cgctgcgcgt gaaaagattg ctgcgggggc ctcactggtg
     8041 caaatttatt ctggttttat ttttaaaggt ccgccgctga ttaaagaaat cgttacccat
     8101 atctaattat ttcttcgaat tcctctttat aagataatca gggctttatt ttaagccctg
     8161 gttgttttat attcatcact gttgcttatt tagacatttt gtacttttat tgttgaggtt
     8221 attaagcgaa gcgacaatgg attgtgttgc tgcggtttta tagggtaggg gagaggcaaa
     8281 tgcgaattaa accagacgat aactggcgtt ggtattacga tgaagagcac gatcgaatga
     8341 tgctcgattt agccaatggt atgctatttc gctcacgttt tgcgcgcaaa atgttgactc
     8401 cagatgcctt ttctcccgca ggcttttgcg ttgacgacgc cgcgctctat ttctcatttg
     8461 aagaaaaatg ccgcgatttt aatttatcta aagaacaaaa agccgaactg gtgcttaatg
     8521 cgctggtagc aattcgttat ctcaaaccgc aaatgccgaa aagctggcat tttgtttccc
     8581 atggtgaaat gtgggtgccc atgccgggcg atgcggcctg cgtttggttg agcgacactc
     8641 acgagcaagt caatttgctg gtcgttgaat ctggcgaaaa tgccgcacta tgcctgctgg
     8701 cacaaccctg cgttgttatt gcgggtcgcg cgatgcagtt gggcgacgcc atcaaaatca
     8761 tgaacgacag gctgaaaccg caggttaatg ttgacagctt cagcctcgaa caggcagttt
     8821 aacgcgtcag cttaagtgca gtcttcggta cacaactaca gcaaagaata gtgccatcat
     8881 cacccattgc tgattttttc agcggcgtga cttcgccttc taaaagctga acacggcaac
     8941 ttccacaaat gcccgcgcgg caagaataag ggatacgaat tccctgattt tctaattgct
     9001 ccagcagcac ctgttggtta tttccacgaa atgcctgtcc ctgccagtca atatctacgt
     9061 ttgcgtccgg ttgttgcgtg atgttggcag tatcatcggc ggcacctgtg ccgtaaattt
     9121 tagctggagc cgttgccaga atttccacct catcgccaac gcgaatcacg ccgctattac
     9181 gggcaattaa attctgacca aaatcgacat cgccgttatc ctgggcagta cggaaagatt
     9241 gcagcgtttt taatggttcg cctgccggat gtttttgccc tttttctggg ctgacggtgg
     9301 tgaaaataca gcggctacaa ggcttaacca catcaaacac gacatcacca atgcgaatca
     9361 ctttccagct atcttcttcc caggtcgatg caccggaaac caccagattg gggcggaatt
     9421 gctccatttt tacactggcc ggacaacgtt gttggagatc acgtaacgag gcctcgttag
     9481 caagaaggta aggatagcca tcagcaaatg acaggggtac agtgttgtgg cgtttcacgc
     9541 gccgggtcat ttgtggcccc acccagcgta attgcacttc gcgggagaaa aatccactta
     9601 gccatttgtt gatcgcgtct ggcgcaattc gcgcggtaaa atgtgtgccc caaacttcgg
     9661 ttggtgcgtc ttgtgtggcg aaatcagcaa aacgaacata tgcgctactg ccatctggtg
     9721 cggtgagatg caagccatca tgcacaggtg aaggaataaa ccgtaccatc tggggaaact
     9781 ggcgagcagt aataaacgta ccgtcaggtt ccgtgatcat aaagatgcga tcgaaggcca
     9841 gaccactgac atctgccaga gcatgtgtaa gaccaatgcc gcgcatcgat ttaacaggat
     9901 gaataaaaag ccgggttaat gtcgccacgg tgcggtcctc aaatgaaaat aagccctcaa
     9961 ctttatgaca tgacgcgctt attagctata atgcgcaaca attttcttag agtaaaagtg
    10021 acgatatgaa ttctctgttt gccagtacgg cccgtgggct ggaagagctg ttaaaaactg
    10081 aactggaaaa cctgggggcc gttgaatgcc aggtggttca gggtggggtc catttcaagg
    10141 gcgacacacg gcttgtttac cagagcctga tgtggagccg cctggcctcg cgtattatgt
    10201 tgccgctggg cgagtgcaag gtttacagcg atttagacct ctatctcggt gttcaggcga
    10261 tcaactggac agagatgttt aatcctggcg cgaccttcgc tgtccacttc agtggtttga
    10321 atgacaccat acgcaacagt cagtacggtg cgatgaaagt gaaagacgcg atcgtcgata
    10381 ctttcacgcg gaaaaatctg ccgcgtccaa atgttgatcg cgatgcgccg gatatccgcg
    10441 ttaacgtctg gctgcataaa gaaaccgcca gtatcgccct tgatctcagt ggtgatggtt
    10501 tacatctgcg tggctatcgt gatcgtgctg gaattgcgcc gatcaaagaa accctggcag
    10561 ccgcgattgt tatgcgatcc ggctggcagc caggaacacc gctgctcgat ccaatgtgtg
    10621 gttctggtac gttgctgatt gaagcggcga tgctggcgac cgatcgcgca ccaggcttgc
    10681 accgtggacg ttggggcttt agcggctggg cgcagcatga tgaagctatc tggcaggaag
    10741 tgaaagcgga agcgcaaact cgtgcccgta aaggcctggc ggagtacagc tcccatttct
    10801 acggttcgga cagtgacgca cgtgtgattc aacgtgcgcg cactaacgcc cgtcttgcgg
    10861 ggattggtga actgatcacc tttgaggtga aagatgtcgc gcaactgacc aatccgctgc
    10921 cgaaagggcc gtacggtaca gtgttgagca acccgccata cggtgaacgt ctggacagcg
    10981 aaccggcgct gattgcgctg catagtctgc tgggccgaat catgaaaaac cagttcggtg
    11041 gctggaatct ctctttgttt agtgcctcgc cggatctgct cagctgcctg cagctgcgtg
    11101 cagacaaaca gtacaaggcg aaaaacggcc cgctggactg cgtacagaaa aactaccatg
    11161 ttgccgaaag cacaccagac agcaaaccgg cgatggtagc ggaagactac gccaaccgtc
    11221 tgcgtaagaa cctcaaaaaa ttcgagaagt gggctcgcca ggaagggatt gaatgttacc
    11281 gcctgtatga cgccgatctg ccggaatata acgttgccgt tgatcgttat gccgactggg
    11341 tggtggtgca ggagtatgcg ccgccaaaaa ctattgatgc gcacaaagcg cgtcagcgtc
    11401 tgttcgatat tatcgctgca accatttcgg tactggggat tgcgccaaac aaactggtgc
    11461 tgaaaacccg tgaacgccag aagggcaaaa atcagtacca gaaactgggc gagaagggcg
    11521 agtttctcga agtcaccgaa tataacgctc acttgtgggt gaacctgacg gattacctcg
    11581 ataccggtct gttcctcgat caccgtatcg cccgtcgtat gctcggtcag atgagcaaag
    11641 gcaaagattt cctcaacctg ttctcttata ccggcagcgc caccgtgcat gcgggattag
    11701 gcggcgcgcg cagcaccacc accgtggata tgtcgcgtac ttatctggag tgggcagaac
    11761 gcaacctgcg tctgaatggc ttaaccgggc gtgcgcatcg cctgattcag gccgattgcc
    11821 tggcgtggct gcgtgaggca aatgaacagt tcgatctgat ctttatcgat ccgccaacct
    11881 tctctaactc aaaacgaatg gaagatgcgt ttgatgttca gcgcgatcat ctggcgctga
    11941 tgaaagattt gaaacgtctg ctgcgtgctg gtgggacgat catgttctcg aacaacaaac
    12001 gcggtttccg tatggatctc gacggtctgg cgaaactggg actgaaagca caagaaatta
    12061 cgcaaaaaac gctctcccag gatttcgccc gtaaccgcca gatccacaac tgctggctga
    12121 ttaccgcagc ctgaaaggaa tagtaatgtc attaatcagt atgcatggcg catggctgtc
    12181 gttcagcgac gtgccgcttc tcgataacgc agaactgcat atcgaagata acgaacgtgt
    12241 ttgtctggta ggtcgtaacg gcgcaggcaa atcgacgtta atgaagatcc tcaaccgtga
    12301 acaggggctg gatgacggtc gcattattta cgagcaagat ttgattgtag ctcgtctgca
    12361 acaggatccg ccgcgtaacg ttgagggtag cgtttatgat ttcgttgccg aaggcattga
    12421 agaacaagcg gaatacctga aacgctatca cgatatttcg cgcctggtga tgaacgaccc
    12481 gagcgagaaa aatctcaacg aactggcgaa ggttcaggaa cagctggatc accacaacct
    12541 gtggcagctg gaaaaccgca tcaacgaagt gctggcgcaa ctgggattag atcctaatgt
    12601 tgcgctgtcg tcgctttccg gcggctggtt gcgtaaagcg gcattaggac gcgcgctggt
    12661 gagcaatccg cgcgtattgc tgctcgacga accgactaac cacctggata tcgaaaccat
    12721 cgactggctg gaagggttcc tcaaaacctt caatgggacg attattttca tctcccacga
    12781 ccgttcgttt atccgcaata tggcgacgcg cattgttgat ctcgatcgcg gcaagctggt
    12841 gacctatcca gggaattacg accagtatct gcttgaaaag gaagaagccc tgcgtgtgga
    12901 agaactacaa aatgccgagt tcgatcgcaa actggcgcag gaagaggtgt ggatccgcca
    12961 ggggatcaaa gcgcgccgta cccgtaatga aggccgcgta cgcgccctga aagcaatgcg
    13021 ccgtgaacgt agccagcgcc gtgaggtcat ggggacggca aagatgcagg tggaagaagc
    13081 cagccgctcc ggaaagatcg ttttcgaaat ggaagacgtt tgctaccagg ttgacggtaa
    13141 gcaactggtg aaagattttt ctgcccaggt tctacgtggc gacaaaattg ccctgattgg
    13201 tccgaatgga tgcggcaaaa ccacgctgct gaaactgatg ctcggtcagc ttcaggcgga
    13261 cagcgggcgt attcacgttg gcaccaaact ggaagtggct tatttcgatc agcaccgtgc
    13321 ggaactggat cccgataaaa cggtgatgga taaccttgcc gaaggtaagc aagaggtgat
    13381 ggttaacggc aagccacgcc acgtattggg ttatttgcag gacttcctgt tccatccgaa
    13441 acgggcgatg acgccggtac gtgcgctttc tggcggtgag cggaaccgct tgctgctggc
    13501 gcgtttgttc ctcaaaccaa gcaacttatt gattcttgac gaaccgacca acgatcttga
    13561 tgtcgaaacg ctggaactgc tggaagaact gatcgacagc taccagggca cggtattgct
    13621 ggttagccac gatcgtcagt ttgtcgataa caccgttaca gaatgctgga tcttcgaagg
    13681 cggcggtaaa attggtcgtt atgtcggcgg ttatcatgat gcccgtggtc agcaagagca
    13741 gtatgtggcg ctcaaacagc ctgcggtgaa aaaaaccgaa gaagccgccg cggcaaaagc
    13801 agaaactgta aaacgcagca gtagcaaact aagctataaa ttgcagcgcg aactggagca
    13861 gctaccgcaa ttgctcgaag atctggaggc gaagctggaa gccctacaga cgcaggtggc
    13921 ggatgcttcc ttcttcagtc agccgcatga gcagacgcaa aaagtgctcg ccgatatggc
    13981 tgctgcagag caggagctgg agcaagcctt tgaacgctgg gagtatcttg aagcgttaaa
    14041 aaatggtggc tgatcgcaaa atagtcgatt taaacagaga cggctgacaa cggtaaaatt
    14101 gcctgatgaa ctgggtttat caggcatgaa aaccaacact ttgttagtca tctgtaaaat
    14161 agcgcatcat taaggagtac caatgtgcga acatcatcat gccgcgaagc acatcctgtg
    14221 ctcgcagtgt gacatgctgg tggcgttacc gcgccttgag catggtcaga aagcggcatg
    14281 tccccggtgt ggcacaacgt taaccgtggc gtgggatgcc cctcggcagc gtcccaccgc
    14341 ctatgcgttg gctgcactgt tcatgctgtt gctgtccaac ttgtttcctt ttgtgaatat
    14401 gaacgttgcg ggagtcacca gtgaaattac attactggaa attcccggcg tgcttttttc
    14461 agaggactac gccagcctcg gcaccttttt cctgttgttt gtgcaactgg ttcccgcgtt
    14521 ttgtctgata accattctgt tactggtgaa tcgcgcggaa ttaccggtcc gtttaaaaga
    14581 gcaactggca cgggtgcttt ttcaactcaa aacctgggga atggcggaga ttttcctcgc
    14641 gggagtgctg gtcagtttcg ttaaactgat ggcctacggc agcattggtg tcggcagtag
    14701 ctttctcccc tggtgtttat tttgtgtcct gcaactgcgc gcctttcagt gcgttgatcg
    14761 tcgctggtta tgggacgata tcgccccgat gccagaactg cgccagccgc taaaacctgg
    14821 cgtcacgggg atacgtcagg ggctgcgttc ttgctcctgt tgtacggcaa tccttcctgc
    14881 tgacgaaccc gtgtgcccgc gttgtagtac caaagggtac gttcgacgta gaaacagcct
    14941 gcaatggaca ctcgcgctgc ttgtaacgtc catcatgctg taccttccgg ctaatatttt
    15001 gcccatcatg gtgacggatt tattaggctc gaagatgcca tcgacgattc tcgctggggt
    15061 catcctgtta tggagcgaag gatcttatcc cgtcgctgcg gttatctttc tggccagtat
    15121 tatggtgcca acgttaaaga tgatcgccat agcgtggttg tgttgggatg ccaaagggca
    15181 tggcaagcgc gacagtgaaa gaatgcattt gatttatgaa gttgttgagt ttgtaggccg
    15241 ctggtcgatg attgacgttt tcgttatcgc ggtgctctcg gcgctggtgc gtatgggagg
    15301 tttaatgagt atttatccgg caatgggtgc attaatgttt gctttagtcg tcataatgac
    15361 aatgttttct gctatgacgt ttgacccgcg tttgtcgtgg gatcgtcaac ctgaatcaga
    15421 gcatgaggag tcctgacagt atggaatcta ataatgggga agccaaaatc cagaaagtga
    15481 agaactggtc tcccgtgtgg atatttccta tcgtcacggc gctcattggg gcctgggttc
    15541 ttttttatca ttacagccat caggggccgg aagtgaccct gatcaccgcg aacgcggaag
    15601 gaatagaagg tggtaaaacc accattaaaa gccgtagcgt tgacgtcggc gtggttgaaa
    15661 gcgccacact ggctgatgat ttgacgcacg ttgaaatcaa agcgcggctg aattccggta
    15721 tggaaaaatt gctgcataaa gataccgtct tttgggtggt gaaaccgcag attggtcgag
    15781 aagggattag cggcctggga acgctgctgt ctggggttta tatcgaactg cagccaggcg
    15841 caaaaggcag caaaatggat aaatacgatt tgctggactc gccaccgttg gccccgcctg
    15901 atgcgaaagg tatccgtgtg attctcgata gcaaaaaagc cgggcagctc tcgccaggag
    15961 atcccgtgct gttccgtggc tatcgggtag gttcggttga aaccagcacc ttcgatacgc
    16021 aaaaacgcaa tatcagctat caactgttca tcaatgcacc ttatgaccga ctggtgacca
    16081 gcaatgttcg cttctggaaa gatagtggca ttgcggttga tttgacgtca gcgggaatgc
    16141 gtgtggagat gggctcattg acaacgctgc ttagtggcgg tgtcagcttt gatgtgccgg
    16201 aaggtctgga tttagggcag ccagtggcac cgaaaacagc tttcgttttg tatgatgatc
    16261 agaagagcat tcaggattcg ttgtacaccg atcacattga ttatctgatg ttctttaaag
    16321 attcggtacg cggtctgcaa ccgggagctc cggtagaatt ccggggtatt cgcctgggta
    16381 ccgtaagcaa agtgccattc tttgcgccga atatgcgtca gacatttaac gatgattacc
    16441 gtattccggt actgattcgt atcgagccag agcggctgaa aatgcagctt ggcgaaaatg
    16501 cggatgttgt tgagcacctt ggcgaattgt tgaaacgtgg tttacgcgga tcgctgaaaa
    16561 ccggaaacct ggtcactggc gcactgtatg ttgatctcga tttctatcca aatacgcctg
    16621 caataaccgg tattcgtgaa tttaatggtt atcagattat cccgaccgtt agcggcggtc
    16681 tggcgcaaat ccagcaacga ctgatggaag cgttggataa gatcaacaaa ctgccattga
    16741 atccgatgat tgaacaggca accagtacgc tttctgaaag tcagcgcaca atgaaaaacc
    16801 tgcaaacgac gctggatagc atgaacaaga tcctcgccag ccagtcgatg cagcagttac
    16861 cgacggatat gcagtcaacg ttgcgtgaat tgaatcgcag tatgcagggc ttccagcctg
    16921 gctccgcagc ctacaacaag atggtggcgg atatgcagcg acttgatcag gtgttgcgag
    16981 aactgcaacc ggtgctgaaa acgctcaacg agaagagtaa cgcgctggta tttgaagcga
    17041 aggacaaaaa agatccagag ccgaagaggg cgaaacaatg aaaaagtggc tagtgacgat
    17101 tgcagcactg tggctggccg gatgcagctc cggcgaaatt aataaaaact attaccagtt
    17161 acctgtggtg cagagcggta cacaaagcac cgccagccag ggtaatcgcc tgttatgggt
    17221 tgagcaggtc gctgttcctg actatctggc ggggaatggt gtggtttatc aaaccagtga
    17281 tgtgaagtat gtgattgcca acaacaactt gtgggccagc ccattggatc aacagttgcg
    17341 caacaccctg gttgccaacc tgagcacgca actgcccggc tgggtggttg cctcccagcc
    17401 tctgggaagc gcccaggaca cgctcaatgt taccgtaacg gagtttaacg gtcgctatga
    17461 tggcaaggtc attgtcagtg gtgaatggct gttgaaccac cagggacaac tgatcaaacg
    17521 tccgttccgt ctggaagggg tgcaaactca ggatggttac gatgagatgg ttaaagtact
    17581 ggccagtgtc tggagtcagg aagccgcttc tattgcgcaa gagataaagc gtctacctta
    17641 attataaaga tttgtaaata taaccgcctc cggtatgttg cctgaggcgg tttttttgtc
    17701 tctaacgtgc ggaaaaagtt gttcctcttc acattttttg tacaactgac atgcccgtgt
    17761 agctcacaaa tatgacagtg gcgtgaattt tgcgcattga cggcagttat gattcgcggt
    17821 attgcttaac tgtgattgca catttagtaa tcactgtttt cttttccacc agaaaccagt
    17881 atgagggaaa cgaggcatga agagacaaaa acgagatcgc ctggaacggg cacatcaacg
    17941 tggttatcag gccggcatag ccggacgctc aaaagaaatg tgtccctatc agacgctgaa
    18001 tcaaaggtca caatggctgg gaggctggcg agaagccatg gcggacaggg tagtaatggc
    18061 ctgattctgt ctctttaaaa agaaacctcc gcattgcgga ggtttcgcct ttttatactc
    18121 tgtctgatta ttatcagaag gcagacgtat cctggaacag accgactttc aggtcgctgg
    18181 cggtatagat cagacgacca tcaaccagca cttcgccatc tgccagaccc ataatcagac
    18241 gacgattaac aatgcgttta aagtgaatac ggtaggtcac ttttttcgct gtcggcagta
    18301 cctgaccagt gaatttcact tcgccaacgc ccagcgcgcg gcctttacct tcgccgccca
    18361 gccagccgag gtagaaccct accagctgcc acattgcgtc caggcccagg catcccggca
    18421 taaccggatc gccaatgaag tggcatccga agaaccacag atccggattg atatccagct
    18481 ctgcttcaac ataccctttg tcgaagttac cacccgtttc ggtcattttg accacacggt
    18541 ccatcatcag catgttcggt gctggcaatt gcgggccttt agcgccaaac agttcaccgc
    18601 gaccagaggc aagaaggtct tcttttgtat aggattcgcg tttatctacc atgttctctg
    18661 taagccttat tttattgaag cacgcaggat agctaacacg tgtacgctga acaagtccga
    18721 tcagttcgga ataaaccagt tcagccaacg taatggccat ggaaaacggt gacgtccttc
    18781 ctgttgcgat gcttgtgcga tacgttcctg gatggtttgc atcagcgtcg tttggccttc
    18841 gccatcccac accagattta ataataacgg cagtgcgtca gtcacatcgt ctactgccca
    18901 gatggtgaat ttgccttctt ctaccgcttt caccagttca ctgtgaagac ttaaatggcg
    18961 aacgttagca gtggggataa tgacaccttg tttccccgtt aactcacgtt gctggcaaat
    19021 agcaaagaag ccttcgattt tctcatttaa accaccgact ggctgggcgc gaccgaactg
    19081 atcgactgaa cctgtgatag cgatactctg attcaccggc acatcggcga gggcgctgat
    19141 cagggcgcag agttcagcca tcgaggcact atcgccatcc acttcactgt atgactgctc
    19201 aaatgtcagc gatgctgaga aggggatctg ttgctcaagc tgtagttccg acatcaggaa
    19261 cgcttgcatg atcatcatcc ctttcgcatg gatattgccg ccaagctccg ctttgcgttc
    19321 gatgtcggtg aattcaccat cgccaatatg cacaacgcag ctaatgcgag aaggttcgcc
    19381 aaaagcgcgt ggatgaccag gaaattcaat gaccgaaagg gcgttaattt gcccgatgcg
    19441 ttcgccttcg gtttcaatca ggatttgctc ctgaaggatc tcatcctgca tgcgttcagc
    19501 gaggaaacct tcacgccatt cacgctgctg cagcattaag tttagctgct cgccggagaa
    19561 ggtgtcgcca tcgcacaggg aggcgacctc tttacactgg cggaggatcc actgcgggct
    19621 aagcggaagt gtttcttgtt caccggtgta gcgggctgct tcgcggataa gtaccggcca
    19681 ggcatccgct cccggtgcag gtaagtgatt atgtcttgcg gtcaatgtta cccagcgaca
    19741 ccactggctt actgactccg catcgacaat ctgcagagta tcttcaaatt cgctataaat
    19801 agcctgctct gaaagctctg gttccatctc ctggaaatca gccaatgatt cgcgttcgcc
    19861 taccagaatg actttcagct tcaatggcat cgaaggcaca gagacgggga gagggcgcga
    19921 ctcatcaaac gcaacccagt caaaacgctc gcggttaacg atatttttca gccgcatcca
    19981 cagcagaggt tgcgccagca gtgtacgcaa agagatgatg agaataccgc catttgcctg
    20041 atgcaccaga ccaggctgca gggtaatgtc gccattaaac tggcgcaggc agccaaagag
    20101 ttgttccgct tctacccagt cggcagcgac aacttgcgtt aaagtcgcaa aattatcatc
    20161 tgcactcact gcgttacgta agcggatggt gtgcccggaa acctcatagt gacagcccac
    20221 cagttggcct gcatcgcttt gtagcgcacg cgcggcatcg gcaataagat tcagatactc
    20281 agactcttcc ggggccttcg ccagcataaa agaggaggat gctcgcgtat gcagcaactg
    20341 ctccagcgca aattgcagtc gcggttgagt atcactgaat aaaggatcgt tttcgtcaat
    20401 caaatgtggc tgagcaaata tttcctgata gctatcggta tcaggaacca ggtcacgcca
    20461 tgcaagtttc gtaatggtca aagttgatgt tttttagtct gttgtcaaag ccgcgattat
    20521 accgtaaccg gcactgcagc acacgtagaa agcaccgaca atactcctgg catgggcgtt
    20581 aaagctcaca ggatggagat tcttttcttc actggcctaa aaagctgata ttctgtaaag
    20641 agttacacgg taacattgag atcgctatga aatatcaaca acttgaaaat cttgaaagcg
    20701 gttggaaatg gaagtatctg gtgaagaagc atcgcgaagg ggagttaatc acccgttaca
    20761 tagaagccag tgccgcccag gaagccgtcg atgtgttgct ctcgctggaa aatgaacccg
    20821 tgctggtaaa tggctggatt gacaagcata tgaatccgga actggtcaat cgcatgaagc
    20881 agaccattcg ggccagacgg aagcgccatt ttaatgcgga acaccagcat acgcgcaaaa
    20941 aatcgatcga tctggaattt attgtctggc aacgtctggc tggtcttgcg cagcgtcgtg
    21001 gtaaaacgct ttctgaaacg attgttcagc tgattgaaga tgcggaaaac aaagagaaat
    21061 acgcgaataa aatgtcttct ttgaagcagg atctgcaggc attgctgggt aaggaataac
    21121 tgacgaaagt cagttcaatt tacgcaaggc gaaaaaaaaa ccccgcagct gcggggtttt
    21181 ttaccagacg agaacttaag cctgcggctg agttacaacg tctttgatac ctttaacttc
    21241 gatctctacg cgacgatccg gagccaggca gtcgatcagt gcagcacgct gtttcacgtt
    21301 gtcacaggtg ttgccagtaa ccgggttgga ttcgcccata ccacgtgcgg agattttgtc
    21361 tgccgggata cctttagaga tcaggtaatc aacaacggac tgagcacgac gctcggacag
    21421 agcctggttg taagcgtcag aaccgatgcg gtcggtgtaa cccagaacaa ctacggaacc
    21481 gtctttcgga tccaggttgc tcagctggct gtacagctga tccagagcag cctgaccttc
    21541 cggtttcagg gttgctttgt tgaaggtgaa cagaacgtca gacttcagag tgaagtgctt
    21601 ggtctgtact tccggtgccg gagctggagc cggagcaact actggagctg cttcgccctg
    21661 accgaaacgg taggaaacac ccaggctcag catgccgttg tccggacgag taccgatggt
    21721 gtgtgcgtca ccgatgttgt tggtccactg gtattccaga cgggtagcga tttcaggagt
    21781 gatcgcgtac tcaacaccgc cagcgaagac cggagaaacg ccggtgtcgt ggtttttacc
    21841 ataaacgttg gatttagtgt ctgcacgcca taccatacca cccagacgag tgtaaacgtc
    21901 cagatcgtca gtgattgggt aacccagttt agcggtcagc tgaacgccct gagctttgta
    21961 tgcgccgttg atgttgtcgc ctttgtacgg catacgacct aaccagtcgt aacccatttc
    22021 aaagccaaca tacgggttaa cctggtaacc accaaaagca ccagcgccca gttggttttc
    22081 atgggtcggg ccattgttgt tgatgaaacc agtgtcatgg tactgggacc agcccagttt
    22141 agcaccagtg taccaggtgt tatctttcgg agcggcctgc gctacggtag cgaaaccagc
    22201 cagtgccact gcaatcgcga tagctgtctt tttcattttt tgcgcctcgt tatcatccaa
    22261 aatacgccat gaatatctcc aacgagataa cacggttaaa tccttcaccg ggggatctgc
    22321 tcaatattaa ctctaccgat atcttcggct tatgccgagc acccctggcg atgtaaagtc
    22381 tacaacgtag ttgaaaactt acaagtgtga actccgtcag gcatatgaaa aaaaagtctt
    22441 gtataaggta cgtttaatct tttttgtcag cgacaattta cagaaaaaaa tcgcggaaac
    22501 cgcttcacac aagcctccgc aaggaaaatt agtcacgact gaaagcattg gctgggcgac
    22561 aaaaaaagtt ccaggattaa tcctaaattt acttaatgat acaaattaga gtgaattttt
    22621 agcccggaaa gttgtctcgt tgcgtgagag gatgcgctta ccggacgcat aataaacccc
    22681 atagcgttac cttcatttgc cgcatcaaca agttcagcat gctcttcttc agtcaaatca
    22741 tctgccaacc aaccgatcac cacactgtaa ttgcccgtgc gtaaagcgcg aaccattgac
    22801 tccacggtgt ggcaagggga gagctggcta atctgcatca ctttcgttaa gggtagccca
    22861 gatgccagaa cccattcccg actcagtttt tgttgcggtg ttaaccagag ttgccagcgc
    22921 gattgctgac cgagttgctg taacaatggc aacagtagaa gttgcgtcat catgggctga
    22981 tcttcgcgat agacaacttc actgataagc ccggctgtag tgttttccgt agagacacgc
    23041 gcaattttac ttgctgcgga tgagaacgac gaagaacgat gtgcatagcc tgaagtgtac
    23101 ataatcaatc cagcccctgt gagttactgt atgaatgtac agtacatcca gtgacgacaa
    23161 agatcaactc tattttcgga aagagcctcg caaattttgt cgttggtgac gggaaaacat
    23221 aaattaatct tgccccttaa gaataagttg cctattttcg tagttaacgg atccgttaat
    23281 gtgaatcatt cttttatgtt atgattttaa aaggaatttt atgaaaagcc tctcctataa
    23341 gcggatctat aaatcacaag aatacctggc aacgttgggc acaattgaat accgatcatt
    23401 gtttggtagt tacagcctga ccgttgacga cacggtgttt gcgatggttt ctgatggtga
    23461 gttgtatctt cgggcttgtg agcaaagtgc acagtactgt gtaaaacatc cgcctgtttg
    23521 gctgacatat aaaaagtgtg gccgatccgt taccctcaat tactatcggg ttgatgaaag
    23581 tctatggcga aatcaactga agctggtgcg tctgtcgaaa tattctctcg atgcagcgct
    23641 gaaagagaaa agcacgcgca atacccggga aagactgaaa gatttgccca atatgtcttt
    23701 tcatctggaa gcgattctcg gggaggtggg gattaaggat gtacgggcgt tacgtatact
    23761 aggggcaaaa atgtgttggt tgcgactgcg gcagcaaaac agtctggtga cagaaaagat
    23821 tctgtttatg cttgaagggg ccattatcgg cattcatgaa gctgcgctcc cggtggcacg
    23881 ccgccaggag cttgcagaat gggctgactc tcttacgccg aaacaggagt ttcctgcgga
    23941 acttgagtaa tctggcgttg cagacgacca atctctggca gtaatgcaat caataaccca
    24001 acttgttgta cgaccagagg ttctttgctg tctgcccgtg gttcaagttg ctgcatccgc
    24061 tgtttcaggc cagctaatgc ctgattgacg cgttcttcat cagcaggttg atgatgtaac
    24121 gcgtcatcaa catagcaaac tgcgtcatca agaaacgcca gaatttcagg attagttaac
    24181 tgctcccggt gagcaccgag ggctgagata tagctggtaa acgtatggtt aaggcacagc
    24241 aaccgaaacg cggcctcacg aatttgcggg gtaacgttcg gctcgctgga catatttgat
    24301 accaccgacg ccagttcagc atcacggttg tgtgcatcgc ggcgggcaat acgatacgcc
    24361 agacggttat cacgcccctg atggtattgc tccagtatgg catcgagata gcgacagttg
    24421 gcctcggtgg cacgttcgag catgcgcggc agattgcgaa acttccagtc aggccagatg
    24481 tagctcaccg ccgcccacgc aatggcacaa ccaatcagcg tatcgattac gcgaggtaac
    24541 gccacttcaa aaccttcacc cagcaagtta aaacaaagta gcaccaaaag tgtgatgaac
    24601 atcgttgcat gggcgtattg cacgttacgg aaggcaaaaa agagcacgcc ggtaataacc
    24661 agtagcacca gttgcccttc cagtgacggt acaaaccaca gcacaggaat gccaatcgcg
    24721 ataccgacca gcgtcccaat aatccttaac ttcaggcggt ggcgagtggc gttatagttt
    24781 ggctggcaga caaacaaact tgtcagcaag atccaatacc cgtgatgcat tccggttatc
    24841 tgaatgatgg cgtagccgaa gcacaacacc agcgacattc ttaccgcatg acggaagagg
    24901 gcggattccg gcgtgaagtg acggctaaga cgcagccaga tatcactcaa tccgtgcggg
    24961 ctgtcatcag cgagctcatt ttcgtcatta ttatggggca gtgcctgggc ctgttctgat
    25021 tcaattgttg ccagttgggc atcaatggcg cgtaaattgt tcagcaaaaa tcccagtgtt
    25081 ttgagtaaat cggcaggtgc gccgttatcg cgcatccgct ccagcgcagc atcaatatgc
    25141 gtaaaagcgc gctcgaaatg cggatcatgt tgataaggct gacgcaacaa aatacaacgt
    25201 gacagttgct ggcacgcctg gccctgcatc gacatcagtc gctgaaaacg gaacagcacg
    25261 tcgctgtggc gaaaatgttc acgcaatgtt tgatactgaa tatgagaaga gctggcacgc
    25321 tcgtgaatat cctgcgcgac aaagtaataa tgcagcgtgc gacgcgttcc ccgttgacca
    25381 cgatcgccac gtaagcgggt cagcagcgag agtttcgtct gattcaatgt cgccatcagt
    25441 tgaccgttgg cgagagccaa atcgtacagc ggtgcctggc tttcatcttc aatatcagga
    25501 tcaaacatgc gcgacttgag ctcaagataa cgcgccagtt gttcatagca acgcgccagg
    25561 ttgtcctgca gcgggcggac cgggaacagc agatgaccaa taagtgtcag gacgttgtac
    25621 cagacggcac cggccagcag atacatcggc tgctgatacc agtgctcata cagtgacgtc
    25681 cccaacatag tgtaaatggc gatcagtaac gcaccgaagg caattgttgc atagcgttga
    25741 cccagaccgc cgagcaaaat gaagccgctg gttgagagcg ttaagccaat cgcaaatagc
    25801 cagggccagg gaaacagcag ttctactgag gccgaggcga taaaaaagca gaacagcgta
    25861 atgatgaggt tacgcaaacg tcccgccagt cggtcatcga gatcggtcag cgccgctgcc
    25921 accatcccca gcgtcagcgg aatcgtcagt tttacatcac ccagccacca cggaaacgct
    25981 gtggttccac aaagcgcaat aaaaatacgc gcgtaataca gccaggcgct gttccaggta
    26041 tagcgtttga gcaaaggact tagcataaag gccatattag tggattattc aaaacgacga
    26101 cgtgcattgg cttcacgcgc agcttgcgct gtttctaccg ataccacgcg acgaccgacc
    26161 ggccatagtg caatagcggc aattttaaag ttcgcaatgc cgacaggaat gccaatgatg
    26221 gaaatacatt gtgcgatgcc cgttgcaatg tgcatcaggc ataaccacca gccaaagaaa
    26281 atcagccaga aaatattcaa taccgtaccg ccagtattta gcagcacatt tttgccagcc
    26341 gggttcagtt catcgacatg aatagcttca ttgccataag gcactagaga cagtttagtg
    26401 atctcccagc aggatcgtgt cagcggtaag gtaaaaatca gcacaatact gaccagagtc
    26461 gccaacagcc agcccagagt ggtggcaaat ccgccaagca caaagttcag aatgttcaaa
    26521 acggtacgca taaaacctcg ctttactgtg gttttcagta atgggcggca attgtaacgt
    26581 ttttttgggc tggagcacgt tttctctgac ggttacactg ataagaaatc atttcgtgtg
    26641 gatctacaga gtcatggaac tgaaagcgac aacgcttgga aaacgtctgg cacagcaccc
    26701 ttacgatcgg gcggtgatcc tcaatgccgg gattaaagtc tccggcgatc gccacgaata
    26761 ccttattcct ttcaatcaat tactggcgat tcactgtaag cgcggtctgg tatggggcga
    26821 gctggaattt gtactgccgg acgaaaaagt ggtgcgtctg cacggcaccg aatggggcga
    26881 gacgcagcgt ttttaccatc atcttgatac tcactggcgg cggtggagtg gggagatgag
    26941 cgaaattgcg tctggcgttt tacgtcagca actggatttg attgccacgc gcaccggaga
    27001 aaataaatgg ctgacgcgtg agcaaacctc tggtgtgcag caacaaatcc gccaggcttt
    27061 gtcggcgttg ccgttgccgg ttaaccgact ggaagaattc gataactgcc gtgaggcgtg
    27121 gcgtaaatgt caggcctggt tgaaggacat tgaaggcgct cggttgcagc ataatcaggc
    27181 gtataccgaa gccatgctta ccgagtatgc ggattttttc cgccaggtcg agtcttcacc
    27241 gctgaatccg gcgcaggccc gggcagtcgt taatggcgag cattctttgt tagtgctggc
    27301 tggtgcagga agcggaaaaa cgtcggtgct ggtggcccgt gcaggctggt tgctggcacg
    27361 tggtgaagcg tcccctgagc aaattttatt gctggcgttt ggtcgcaaag ccgctgaaga
    27421 gatggacgag cgtattcgcg aacggctaca taccgaagac attaccgcac gcacatttca
    27481 tgcgctggcg ctgcatatta ttcagcaggg cagcaaaaaa gttccgatag tcagcaaact
    27541 ggaaaatgat accgctgccc gtcatgaact ttttattgct gagtggcgca agcaatgcag
    27601 cgaaaagaaa gcgcaggcga agggctggcg gcaatggctg acggaagaaa tgcagtggtc
    27661 agtgccagaa ggtaacttct gggatgatga aaaattacag cgtcgtcttg cctcacgcct
    27721 cgatcgttgg gtaagtctga tgcggatgca cggtggtgca caggcagaaa tgattgccag
    27781 tgcacccgaa gagattcgcg atctgttcag taaacgtatc aagttgatgg ctccgttatt
    27841 aaaagcctgg aaaggtgcgc tgaaggcaga aaacgctgtc gatttttcgg gccttattca
    27901 ccaggcgatt gtgattctgg agaaaggtcg ctttatcagc ccgtggaagc atattctggt
    27961 tgatgaattt caggatatct cgccgcagcg cgcagcgttg ttagcggcat tacgcaagca
    28021 aaacagtcag acgacgttgt tcgccgttgg tgatgactgg caggcgattt atcgcttcag
    28081 cggtgcgcaa atgtcgctca ccaccgcttt ccatgaaaac tttggtgaag gtgatcgctg
    28141 cgatttagac acgacttacc gttttaacag tcgtatcggt gaggtggcaa accggtttat
    28201 tcagcagaac ccaggccagc tgaaaaagcc gctaaacagc ttaaccaatg gagacaaaaa
    28261 agccgtcacg ttattggatg agagccatct tgacgctttg ctggataagc tctctggtta
    28321 tgccaaaccg gaagagcgca ttctgatcct ggcgcgttac catcacatga ggcctgccag
    28381 cctggaaaaa gcggcaacac gctggccgaa gttgcaaatc gactttatga ccattcatgc
    28441 cagcaaaggg caacaggcgg attacgtcat catcgttggc ttgcaggagg ggagtgatgg
    28501 ttttccggct gcggcgcggg agtcgattat ggaagaggcg ctactgccac cggttgagga
    28561 tttcccggac gctgaagaac ggcggttaat gtacgtggcg ctgacccggg cacgccatcg
    28621 ggtatgggca ctgtttaaca aagagaatcc ctctccattt gtcgaaatac tgaaaaatct
    28681 ggatgtgccg gtggcgagaa aaccgtaaaa aacaggtggc gtttgccacc tgtgcaatat
    28741 tacttcagac ggtccgcgag ataacgctga taatcgggga tcagaatatc gaccgcatcg
    28801 ttgaaatgcg gcgactggat aatgaagtct gccgttgcca cgttggtggc gaccggaatg
    28861 ttccataccg tcgccagacg cagcaaggct ttcacgtcag ggtcgtgcgg cacggcgttt
    28921 agtgggtccc agaagaaaat caatacatca attttccctt ctgagatcaa tgcgccaacc
    28981 tgctggtcac cccccattgg gccactcaac atcgcgttga cgttcatgcc ggttgcacgg
    29041 gaaatcaagt taccggtagt gcctgttgca tacagtacgt gttgttccag taacggttga
    29101 tgtcgttcca cccagctcat cagcatttgt ttgcagtgat cgtgtgccac cagcgcaata
    29161 tgtttccgcg caggtaaagt gcgtgtcgtc agttccataa tgtacatccg tagttaactt
    29221 tcctacagat tactgtaagc acttatcgct gcaagagaaa gaccgaaaaa gcctgcgcac
    29281 aggcacaaaa atctcaggaa gatggttgtt tttccgccca ttgcaggaaa gtatttcgcg
    29341 tttgtgggtc agccagttta aaccaatact tcagccgttg ttctgtgagc acctgagact
    29401 gcggtggaat agcatccagc tcggaaacac ccgaaagcag cgtactgtca tctgccatca
    29461 tcgtggcaaa ttgcggtagt gaagcgcgtt tcgcggattt gttatagcgt tcaacctcga
    29521 cctcataatc aatcgttttt gccgttgagg taatggcgag aatatccagc tttaccggaa
    29581 tcggcgtcgc atcgccatcc aacaattcaa ggcgcggcgc ggcatcaaaa tggttagctt
    29641 cccgctcatt ctccaggcga ggcaggcgaa aattgacctg gttgatgagc tgggtattaa
    29701 aactgaccac cagcggtggg gagatataca gccgttcttc actattggaa agatgaatcg
    29761 tcttctcaac gcgaaacact aactgatgcg gtccgttatc cagttcaatg ctgtccgcac
    29821 cgcgcagcag agagctggaa accttcttgc cgtcgagtac cagaagatcg acatcggttg
    29881 aaagccgcaa cgtggtggca aaaacggata ccggcaaaca taatgcaatc aaggtggtca
    29941 cgatgccggt tttcataggt agctcctgtc aaaagaccgc ccgaataata atgtgtcaaa
    30001 atttttcttt aatcatactt actaacatat agacatattt cccgcttttg ctctcattca
    30061 ttcgtattag ctgcatggtt ggcatgtcgg ctttgtcgta cactttgtta aacagtctgg
    30121 aggaaataat gaaagaaacc gatattgcag gcattttaac gtccactcac accattgcgc
    30181 tggtgggggc aagcgacaaa cccgatcgtc ccagctatcg cgtgatgaaa tatctactag
    30241 accaggggta tcacgtcatt ccggtttcgc caaaagttgc tggcaaaaca ctgctgggcc
    30301 agcaggggta tggcacgctg gcagaagttc ctgaaaaagt cgatatggtc gatgttttcc
    30361 ggaattcaga agcagcgtgg ggcgtagcgc aggaagcgat cgccatcggc gcgaaaaccc
    30421 tctggatgca actgggggtg attaatgagc aagcggcagt actggcacgg gatgccggat
    30481 taaatgtagt gatggatcgc tgcccggcta ttgagatccc tcgcctgggc ctggccaaat
    30541 aaaaaatccc cggaaggcaa aaaccttccg gggatttgtt cagggattag ttacgcagac
    30601 gcggggcctg gagttgtttg cggatggtct gcgccagctc atccatggat ggctgttcag
    30661 gatgttcatc ctgcaattcg ctacttagct gggcttcagc caggtaggta tgaaccggta
    30721 ggccgttatc gtcctccatc accacgtgat accacggagc ggcgcgaagc tcgtcattca
    30781 ccgccagctc atcaggcgac ggttcagaga gcgaataaac cgggtcgata tccacgacca
    30841 ctccgagata acctaacagg gaatggcgga cctgctggcc gataccgaat ttgctggcaa
    30901 tcatagtcac ctcccgggaa atctttacct ttgatataag ggtaaaattc cacatttcaa
    30961 gttacatgac gcgacaggca aaccctttca gatatagccc ttccggatag gtagcgatca
    31021 ccggatgatc ggctgcctga cggaactgct ctataaattg tacatcacga ccggcatcaa
    31081 ttgcggcatc cgcgatgatt ttctgaaata aatcgctggt catcaggcca gaacaggaga
    31141 aagtcaggag aactccgcct tcattcagca actgaatcgc cagcatgttg atgtctttat
    31201 agccacgaca cgcgcccatc aactggcttt tattctcaac aaacttcggc gggtccatca
    31261 cgataacgtc aaatttttca ccgcgatcgc gataggtacg cagcaattta aagacatcat
    31321 cacggacaaa ctcagccttg ctcagatcca gtttgttcag ctcaacgttc tgccgtgcaa
    31381 tatccagggc ttcctgggag gtatcaacgc tgacaacctg gctgcaaccg cccatcagtg
    31441 ccgatacggc gaaaccaccg gtataggaga aacagttcag tacgcgttta ttttcaacgt
    31501 agcggcgggt agccaggcgg ctatcacgct gatccaggta gtagcccgtt ttgtgtccgt
    31561 gctgaatatc caccagcagc ttcatgccgt gttcttcaat cggcagcagg gcaggcggca
    31621 actcgccggt gacggggccc tgggtcagct ccatcccttc ttttttacgt accgcgacgt
    31681 cgctgcgatc gtaaatcgca cattccgggt acagcgtttg cagggcacta attaatgccg
    31741 cgcgctgata ttctgcccca gcactcagca gttgcagcac cagaaaatta ccgaaacgat
    31801 cgatagtaat acccggcagg ccatcagatt ctccggcgat taaacgatag ctgttgaggc
    31861 catctttttg cgccagccag tcacgccatt tttgtgcttg ttgtaaacgt cgggtaaaaa
    31921 aagcaatgtc gatagattca ttcgggtcaa acgtccagac gcgcgcccgg atttgcgaag
    31981 ctggcgaata agcgccgcgt gctaaccatt ttccctgatg atcaacaata tcgatggttt
    32041 caccgaggct ggctttacct tccatgcggg caacggcccc ggaaaagatc cacggatggc
    32101 gacgaagtaa tgatttttcg cgccctttgg ctaacactaa acgtacactc ataatttact
    32161 tttctgtcga tgcaaagaaa tgggcgtcat tgtccggagt tttccatgga tttgcaacgc
    32221 gtccattaag gataaggaga gcagcaatgt cgaaagtctg cataattgcc tgggtttacg
    32281 ggcgagttca gggcgtagga ttccgctaca ccacgcagta cgaagcgaaa aaactgggac
    32341 taaccgggta cgccaaaaat cttgacgatg gcagcgtgga agtggttgcc tgcggtgaag
    32401 aagggcaggt ggaaaaatta atgcagtggt taaaaagtgg cggcccgcgt tcagcgcgtg
    32461 tggaacgggt gcttagcgag ccgcatcatc cctccgggga gttaacggat tttcgtatcc
    32521 gttaaatgca ttttaccggt ttaggcaggc cagcaatttt ggtggcttgc tttgccggac
    32581 ctttcgggaa cagtcggtac agatagcggc tattgccttt ctcttcgcca aatttattcg
    32641 ccatcgcttt taccagcata cgaatcgccg gagaagtatt gaattccaga tagaaatcac
    32701 gcacaaaacg caccacttcc cagtgttctg gcgacagcgc aatcccttcg ttctctgcaa
    32761 tcaccaccgc cagtggctca ctccactggc tgctttcttt gagatagcct tcggtatccg
    32821 tttctatctc tttaccttcg aagatcagca taattcttta ctaccttaat cagactggcg
    32881 gcagtgtaac aaaaaacaaa gccccgcata aagcgaggct atgaaagtgt tagcgggtga
    32941 gattaatcgc ggctggcgaa gcccagaatg ctcagcaggc tgacgaagat gttgtacagc
    33001 gaaacataca ggctaaccgt ggcacgaata tagttcgttt caccgccatg aatgatgttg
    33061 ctggtttcaa acaaaatagc gccagaggag atcagaatga agaccgcgct gatcgccaga
    33121 tgcagagcag gcagttgcag gaagatatta gcaaccatac caatcagcac caccacaata
    33181 cccgccatca gcataccgcc aaggaacgac atatctttgc gggtggtcag cacatacgca
    33241 gagcagcaga agaacactaa cgccgttccg cccagtgcca tagcgattac gtcacccatt
    33301 ccggcagaca ggtaggtgtt cagaattggt ccgaggatat atcccagaaa accggtaaag
    33361 gcgaatgcgg agataatccc ggtcggctta ttcgccgttt tataggtcag gaacatcaaa
    33421 ccatacatac ccaccagcgt cagaatcaga cccggagatg gcagcatcag caccgtactg
    33481 gcagttgcgg taatcgccga aaaggccagc gtcaggctca gcagaaaata ggtattacgc
    33541 agcaccttat gggtgctaag cagtgatgta cggtcatgtg aagaactaac aatacgatcc
    33601 attgagtcac tctctatgac agatgtaatt aattaagcag cataatgata atgcgtaagg
    33661 gcacccagaa gttttaccca tctttacgca tttgatctgg aacaggttta acagcggatt
    33721 atcaggtcat taagcaaata taacgccctg agaatttcga caggcaaaag aaaaaggggt
    33781 tagcatttag ctaacccctt cttttatctg gcggaagcgc agagattcga actctggaac
    33841 cctttcgggt cgccggtttt caagaccggt gccttcaacc gctcggccac acttccggaa
    33901 tgacgcgcac tataaacatc ccgatgcggc gtgtaaaccc ctaatatgtt tgtttgcctg
    33961 aaaaacagcc aaaaatgcat tgatagcgtg aaataacagc aaattgatca tttcatcacc
    34021 atgaattcct tctcttttac tcgtttagca accggctaaa catccccacc gcccggccaa
    34081 agaaaaatag gtccattttt atcgctaaaa gataaatcca cacggtttgt attgttttgt
    34141 gcaaaagttt cactacgctt tattaacaat actttctggc gacgtgcgcc agtgcagaag
    34201 gatgagcttt cgttttcagc atctcacgtg aagcgatggt ttgccttgct acagggacgt
    34261 cgcttgccga ccataagcgc ccggtgtcct gccggtgtcg caaggagaag agacgtgcga
    34321 tatgaataac gaggaaacat tttaccaggc catgcggcgt cagggcgtta cccggcgcag
    34381 ctttctcaaa tattgcagtc tggctgccac gtcgctggga ttaggcgcgg gaatggcacc
    34441 aaagattgcc tgggcgctgg agaacaaacc gcgcattccg gtggtatgga tccacggtct
    34501 ggaatgcacc tgctgtaccg aatcttttat ccgctccgct cacccgctgg caaaggacgt
    34561 catcctttcc ctgatttccc tcgattacga cgatactttg atggctgccg ccggaaccca
    34621 ggcggaagaa gtctttgaag acatcatcac gcaatacaat ggcaaatata tcctcgcagt
    34681 agaaggtaat ccgccgctgg gcgagcaggg gatgttctgt atcagcagcg gacgaccgtt
    34741 tattgagaaa ctcaaacgtg ccgctgccgg agccagtgcg attatcgcct ggggaacctg
    34801 cgcgtcctgg ggctgcgtgc aggccgcgcg acccaatccg acgcaggcaa cgcctatcga
    34861 caaagtcatc accgacaaac ctattatcaa agtacctggc tgcccgccga tcccggatgt
    34921 gatgagcgcc atcattactt acatggtgac ctttgatcgc ttgccagatg tcgacagaat
    34981 gggccgtccg ttgatgttct atggtcagcg aatccacgat aaatgctatc gccgcgccca
    35041 cttcgacgcc ggagagttcg tccagagttg ggacgatgac gctgcccgca aaggttactg
    35101 cctgtacaaa atgggctgca aagggcctac cacctataac gcctgttcct ccacacgctg
    35161 gaatgatggc gtttctttcc caatccagtc tggtcacggc tgcctgggct gtgcggaaaa
    35221 tggtttctgg gatcgcggtt cgttctacag ccgcgtggtc gatattccgc aaatgggtac
    35281 tcattccacc gccgataccg tcggcttaac cgcgcttggc gtggtggcag cggctgttgg
    35341 tgtgcacgca gtcgccagcg ccgttgacca gcgcagacgt cataaccagc aacctacaga
    35401 aaccgaacat cagccaggca atgaggataa acaggcatga gcactcagta cgaaactcag
    35461 ggatacacca tcaataatgc cggacgccgc ctggtggtcg acccgattac gcgcattgaa
    35521 ggccacatgc gctgcgaagt gaatattaac gatcagaatg tgatcaccaa tgccgtctcc
    35581 tgcggcacca tgtttcgcgg actggagatc atcctgcaag ggcgtgaccc gcgcgatgcg
    35641 tgggcgttcg ttgaacgtat ttgcggtgtc tgtactggcg tacacgccct ggcttcggtt
    35701 tacgccatcg aagatgccat cggtattaaa gtgccggaca atgccaatat catccgcaac
    35761 attatgctgg cgacgctctg gtgccatgac catctggtgc acttttatca gcttgccggg
    35821 atggactgga tcgatgtgtt agatgcgctg aaagccgatc cgcggaaaac ctccgaactg
    35881 gcgcaaagtc tctcctcatg gccgaaatca tcccctggct atttcttcga cgtacaaaac
    35941 cgcctgaaga aattcgttga aggcgggcag ttggggatct tccgcaatgg ctactggggg
    36001 cacccgcagt acaaactgcc gccagaagcc aacctgatgg gctttgccca ctatcttgaa
    36061 gctctcgatt tccagcgtga aattgtcaaa atccacgcgg tctttggcgg taaaaacccg
    36121 catccaaact ggattgtcgg cgggatgcct tgcgccatta acattgacga aagcggcgcg
    36181 gtcggggcgg tcaatatgga acgcctgaac ctggtgcagt caatcattac ccgtacggcg
    36241 gatttcatta acaacgtgat gatccccgac gccttagcca tcggtcagtt caacaagccg
    36301 tggagcgaaa tcggcactgg cctttcggat aaatgcgttc tcagttacgg cgcgttcccg
    36361 gatatcgcca acgactttgg cgagaaaagt ctgctgatgc ctggcggcgc ggtgattaac
    36421 ggcgacttca acaatgtgct gccagtggat ttggttgatc cgcagcaggt gcaggagttt
    36481 gtcgatcacg cctggtatcg ttatcccaac gatcaggtcg ggcgtcatcc gttcgatggt
    36541 attaccgacc cgtggtacaa ccccggcgat gtcaaaggca gcgataccaa cattcagcag
    36601 ctgaatgaac aggaacgcta ctcgtggatc aaagcgccac gctggcgcgg taacgcgatg
    36661 gaagtggggc cgctggcacg cacgttaatc gcttatcaca aaggcgatgc ggcgaccgtt
    36721 gagtcggtcg atcgcatgat gtcggcgttg aacctaccgc tttccggcat ccagtcaacg
    36781 ttaggccgca ttttgtgtcg cgcgcacgaa gcgcagtggg ccgcaggcaa gttgcaatat
    36841 ttcttcgaca agctgatgac caatctcaaa aacggcaatc tcgccaccgc ctccactgag
    36901 aagtgggaac cagcaacctg gccgacagag tgccgtggtg tcggctttac cgaagcgccg
    36961 cgcggagcgt taggccactg ggccgccatt cgcgatggca agattgatct ctaccagtgc
    37021 gtggtgccga ccacctggaa cgccagcccg cgcgatccta aagggcaaat tggcgcttat
    37081 gaagcggcgc tgatgaacac caaaatggcg atccccgagc aaccgctgga gatcctgcgt
    37141 actctgcaca gctttgatcc gtgcctcgcc tgttcaacac acgtgctggg cgacgacggt
    37201 agcgagctga tctccgtgca ggtgcgttaa cagcgaagga gaatcatcat gcaacagaaa
    37261 agcgacaacg ttgtcagcca ctatgtcttt gaagcgccag tgcgtatctg gcactggctg
    37321 acggtgttat gcatggcggt gttgatggtc accggttact ttatcggcaa gccgctacct
    37381 tccgtcagcg gcgaggcgac gtatctgttc tatatgggct acatcaggtt aattcacttc
    37441 agcgccggga tgatttttac cgtggttttg ctgatgcgga tctactgggc ttttgttggc
    37501 aatcgttact cccgcgagct gtttatcgtg ccggtatggc gtaaaagctg gtggcagggc
    37561 gtgtggtatg aaatccgctg gtatctgttt ctggcaaaac gtccgagtgc cgatataggc
    37621 cataacccca tcgcccaggc ggcgatgttc ggctatttcc tgatgtcagt ttttatgatc
    37681 atcaccggct ttgcgctgta cagcgaacac agccagtacg ctatttttgc gccgttccgt
    37741 tatgtggtgg aatttttcta ctggacgggc ggcaactcaa tggacattca cagctggcat
    37801 cggctgggga tgtggctgat tggcgcgttt gtgatcggtc atgtctacat ggcgctgcgt
    37861 gaagacatca tgtccgacga cacagtgatc tccaccatgg tcaacggcta ccgtagccac
    37921 aaatttggca aaataagtaa caaggagcgt tcatgagcga gcaacgcgtg gtggtaatgg
    37981 ggctgggcaa cctgctgtgg gccgatgaag gcttcggcgt gcgggtggcg gaacggttgt
    38041 atgcccatta ccactggccc gatgaagtcg agattgttga tggcggcact cagggactga
    38101 acttgctggg gtatgtcgaa agcgccagcc acttgctgat tctcgacgcc attgattacg
    38161 ggctggaacc cggaacgctg cgaacctatg ccggagaacg cattccggcc tatctcagcg
    38221 cgaagaaaat gagcctgcac cagaacagtt tctccgaagt actggcgctg gcagatatcc
    38281 gcggaaatct gccagcacat attgccctcg tcggcctgca acccgcgatg ctcgacgact
    38341 acggcggcag cctgagcgaa ctggcgcggg agcaactgcc cgccgcggaa caggcggcgc
    38401 tggtacagct ggcggcctgg ggaattgtac cgcaaccgac tgaggagttg cgctgtctca
    38461 attatgactg tctgtcgatg gaaaattacg aaggcgttcg cttgcgtcag tacaagatga
    38521 ggctggagga acagggatga gcaacgacac accatttgat gcgttgtggc aacgaatgct
    38581 ggcgcgcggc tggacgccga tcagtgaatc ccgtcttgac gactggctta cgcaagcgcc
    38641 agacggcgtg gtgttattaa gtagtgaccc gaaacgcacg ccagaagtca gcgataaccc
    38701 ggtcatgatt ggcgaattac tgcgcgagtt tcccgactat acatggcagg tagcgattgc
    38761 tgatcttgag cagagcgaag ccatcggcga tcgctttggc gtctttcgct ttcccgccac
    38821 attagtgttt accggcggaa actatcgcgg cgtgctgaat ggtattcacc cgtgggcgga
    38881 actgataaac ctgatgcgtg ggcttgtcga accacaacag gagcgtgcct catgagcgaa
    38941 acttttttcc atctgctggg gccaggaacg caaccgaacg atgacagttt cagcatgaat
    39001 ccactgccga tcacctgtca ggtgaatgat gaaccgagta tggcggccct ggagcaatgt
    39061 gctcacagcc cgcaggtgat tgcgctgtta aacgagttac aacatcaact aagcgaacgc
    39121 cagccgccgt tgggcgaggt gctggcagtc gatctgttaa atctcaacgc cgacgatcgt
    39181 cactttatca atacgcttct cggggaaggg gaagtgtcag tgcgcataca gcaggctgac
    39241 gacagtgaaa gtgaaataca ggaggcgatc ttctgcggat tatggcgggt gcgcagacgt
    39301 cgcggcgaca agttgctgga ggacaaactg gaggctggct gcgcgccgct ggcattgtgg
    39361 caggcggcaa cgcaaaacgt cttgccgaca gattcgctgt taccgccgcc cattgatggc
    39421 ctgatgaatg gcctaccgtt ggcgcatgag ctactggcgc atgtacgtaa ccccgacgcg
    39481 cagccgcaca gcattaatct gacgcaatta cccatcagcg aggctgatcg gctttttctc
    39541 tcacgtctct gtgggccggg aaatattcag attcgtacca ttggctatgg cgagagctat
    39601 atcaacgcca cggggttacg ccatgtctgg catttacgct gtacggacac cttaaaaggc
    39661 ccgttactgg aaagttatga aatctgccca ataccggaag tggtgctggc agcgccagaa
    39721 gatttggtcg actctgcgca gcggcttagc gaggtatgtc agtggctggc ggaaggtgca
    39781 ccgacgtaaa aagacggtaa gtatcgcttt cagtcttatg aatatcgcaa tcggcgaata
    39841 cctctggtcg tagagtttca ggataaagag ggagatctac cattatcggg ttatttttct
    39901 ctcttcgcct acaggagtgc gcatgtggga tgtcattgat ttatcgcgct ggcagtttgc
    39961 actgaccgcg ctgtatcact ttttatttgt accccttacc ctggggctga tttttttgct
    40021 ggctatcatg gaaaccattt acgtggtcac cggcaaaaca atctaccgcg atatgacgcg
    40081 cttctggggt aagctcttcg gtatcaactt tgctcttggc gtggctaccg gcctgaccat
    40141 ggagtttcag tttggtacta actggtcatt ctattccaac tatgtgggcg atatttttgg
    40201 cgcaccgctg gcaatggaag cattaatggc cttcttcctc gaatccacct ttgtcgggct
    40261 gttcttcttc ggctggcagc ggctgaataa ataccagcac ctgctggtga cgtggctggt
    40321 ggcgttcggt tcaaatctct ctgcattgtg gatattgaat gccaacggtt ggatgcaata
    40381 cccgaccggt gcgcattttg atatcgacac cctgcgtatg gagatgacca gtttcagcga
    40441 gttggtcttt aacccggtca gccaggtgaa atttgtgcac accgtaatgg cgggatacgt
    40501 gaccggggcc atgtttatta tggcgatcag cgcctggtat ttactgcgcg gacgggagcg
    40561 cgatgtcgca ttacgctcgt ttgccatcgg ttccgtcttc ggtactctgg cgattatcgg
    40621 tacgctgcaa ctcggagaca gttctgcgta tgaagtcgcg caagtacaac cggtaaaact
    40681 ggcggcgatg gaaggggagt ggcaaacaga acctgcacct gcaccgttcc atgtggttgc
    40741 ctggccggaa caggatcaag agcgtaacgc ctttgccatc aaaattcccg cgctgctagg
    40801 gatcctcgcc actcactcat tagataaacc cgtgccgggt ctgaagaatt tgatggctga
    40861 aacctaccca cgcttgcaac gcggacgtat ggcctggctg ttaatgcagg aaatatcgca
    40921 aggcaatcgt gagccgcatg tgttgcaggc attccgggag ctggaaggcg acctgggtta
    40981 cggcatgttg ctctcccgct atgcgccgga tatgaatcat gtcacagcca cacagtacca
    41041 ggcggcgatg cgtggcgcga tacctcaggt tgcgccggta ttctggagtt tccgcatcat
    41101 ggtaggctgt ggttccctgc tgttactggt gatgctgatt gcgcttgtcc agacgctgcg
    41161 tggcaaaatc gaccagcatc gctgggtgct gaaaatggcg ctctggagtt tgccgcttcc
    41221 gtggattgcg attgaagccg gatggtttat gaccgagttt ggtcgtcagc cgtgggcgat
    41281 acaggacatc ttaccgacat actccgcgca ctccgcctta accacaggac aactggcttt
    41341 ctcactgatc atgatcgtag ggctttacac cctgttctta atcgccgaag tctacctgat
    41401 gcagaaatat gcccgtctgg ggccgagcgc gatgcagagt gaacaaccga cgcagcaaca
    41461 ggggtaaagg agaaaatcat gtttgattat gaaacattgc gcttcatctg gtggctgctg
    41521 attggcgtga tcctggtggt ctttatggtc tccgacggat ttgacatggg gatcggctgt
    41581 ctgctgccgc tggtggcgcg taatgatgat gaacgtcgga tagtgataaa cagcgttggc
    41641 gcgcactggg aaggcaatca ggtctggttg atcctcgcag gtggggcatt atttgccgcc
    41701 tggcccagag tgtatgcagc ggcgttttcc ggcttttatg tggcgatgat cctggtgctg
    41761 tgctcgctgt tcttccgccc gctggccttt gattatcgcg gaaaaattgc cgatgcacgc
    41821 tggcgtaaaa tgtgggatgc cggtctggtc atcggcagtc tggtgccgcc ggtagtcttc
    41881 ggtatcgcct tcggcaactt gttgctcggc gtgccgtttg cctttacacc gcaattacgc
    41941 gtggagtatc tcggcagctt ctggcaactg ctgacgccat tccctttatt gtgcggattg
    42001 ctcagccttg ggatggtgat tttgcaaggt ggcgtctggt tacaactgaa aactgttggt
    42061 gtgattcatc tgcgttcaca gctcgcgacc aaacgcgccg cactactggt gatgctgtgc
    42121 tttttgctgg cgggttactg gctgtgggtc ggtattgatg gctttgtact gctcgcccag
    42181 gatgctaacg gtccttccaa tccgttaatg aaactggtgg cagtgctacc tggtgcctgg
    42241 atgaataatt ttgtcgaatc gcccgttttg tggatcttcc cgctgctggg gttcttctgc
    42301 ccattgctga cggtgatggc gatttatcgt ggtcgcccgg gttggggatt tttgatggca
    42361 tcattgatgc aatttggcgt gattttcacg gcaggcatca cgctgttccc ctttgtcatg
    42421 ccgtcaagcg tgagtctaat ctccagcctg acgttgtggg acagcacttc cagtcagctg
    42481 acgctgagca ttatgttggt aatcgtgctg atatttttgc ctattgtgtt gctctacact
    42541 ctctggagct actacaaaat gtggggacgc atgacgacag aaactctccg ccgtaacgaa
    42601 aacgagctgt actaaggagc aggaacaatg tggtatttac tttggttcgt cggcattttg
    42661 ttgatgtgtt cgctctccac ccttgtgttg gtatggctgg acccgcgtct gaaaagttaa
    42721 cgaacgtaag cctgatgtgg cgcattagca tcgcatcagg caatcaataa tgtcagatat
    42781 gaaaagcgga aacatatcga tgaaagcgat cttaatccca ttcttatctc ttctgattcc
    42841 gttcaccccg caatctgcat tcgctcagag tgagccggag ctgaagctgg aaagtgtggt
    42901 gattgtcagt cgtcatggtg tgcgtgctcc aaccaaggcc acgcaactga tgcaggatgt
    42961 caccccagac gcatggccaa cctggccggt aaaactgggt tggctgacac cgcgcggtgg
    43021 tgagctgatc gcctatctcg gacattacca acgccagcgt ctggtagccg acggattgct
    43081 gacgaaaaag ggctgcccgc agcctggtca ggtcgcgatt attgctgatg tcgacgagcg
    43141 tacccgtaaa acaggcgaag ccttcgccgc cgggctggca cctgactgtg caataaccgt
    43201 acatacccag gcagatacgt ccagtcccga tccgttattt aatcctctaa aaaatggcgt
    43261 ttgccaactg gataacgcga atgtgactga cgcgatcctc agcagggcag gagggtcaat
    43321 tgctgacttt accgggcatc ggcaaacggc gtttcgcgaa ctggaacagg tgcttaattt
    43381 cccacaatca aacttgtgcc ttaaccgtga gaaacaggac aaaagttgtt cattaacgca
    43441 ggcattacca tcggaactca aggtgagcgc cgacaatgtc tcattaaccg gtgcggtaag
    43501 cctagcgtca atgctgacgg agatatttct cctgcaacag gcacaaggaa tgccggagcc
    43561 ggggtgggga aggatcactg attcacacca gtggaacacc ttgctaagtt tgcataacgc
    43621 gcaattttat ttactacaac gcacgccaga ggttgcccgc agtcgcgcca ccccgttatt
    43681 ggatttgatc atggcagcgt tgacgcccca tccaccgcaa aaacaggcgt atggtgtgac
    43741 attacccact tcagtgctgt ttatcgccgg acacgatact aatctggcaa atctcggcgg
    43801 cgcactggag ctcaactgga cgcttcctgg tcagccggat aacacgccgc caggaggtga
    43861 actggtgttt gaacgctggc gtcggcttag cgataacagc cagtggattc aggtttcgct
    43921 ggtctttcag actttacagc agatgcgtga taaaacgccg ctatcattaa atacgccgcc
    43981 cggagaggtg aaactgaccc tggcaggatg tgaagagcga aacgcgcagg gcatgtgttc
    44041 gttggccggt tttacgcaaa tcgtgaatga agcacgcata ccggcgtgcg ctctccatca
    44101 agacaaataa acatttgccg ctgttggtcc tcgcaggcca tttacgcggc aaaattccac
    44161 gcgtaatcct ggtataagca cttctgcgtc gcggggagtg aatgcggaaa tatggacctg
    44221 gacttcttta cgaccgtcgg aggggataat gaatcctttg ccgcttttgc gatcaaaggt
    44281 tttgacaatt cctgtcattt tacgggacaa acaaattcct tactgaaaat actgcgctgc
    44341 actatacggg gttaataaaa taaagccagc gatatttaag accgccggac ggctaaaata
    44401 aaatttgctt aatctcaatt atcatgcgtt aatagctgcg tcggtttgaa agacagacag
    44461 catacaaagt agtttactaa agcagttctc attatcaggc attatcccct tcttttgagt
    44521 ctctctcctg aacactaagt agtttctgta ttaaagccct gtttgccgaa aggcccaaaa
    44581 tgaaggaagt aaaatatgtc taataaaatg actggtttag taaaatggtt taacgcagat
    44641 aaaggttttg gctttatcac tcctgatgat ggcagcaaag acgttttcgt ccatttcacc
    44701 gccatccaga gcaatgaatt ccgcacgctg aacgaaaatc agaaagttga attttctatt
    44761 gagcaggggc aacgtggtcc cgcggcagcg aacgttgtta cgctctaagg ttgccgttat
    44821 tactcaacat ctccatttcc gctgtccatg ttgtcatggt tcacagtacc gcacatcggc
    44881 attcgatgtg acggagcgaa atcctttagg ggcaaagtgt attttttgta aatcgacgat
    44941 gatcaccttt gataacgtcg cgctgcaaat acgcactgag catgcgccgc tggatttcac
    45001 aaaataatat caggctccct cgtggagcct tttttatatc tgccttattt ttcttcaacg
    45061 ctgtatgtat agtaagcgat aacctgttga ttattgaatc tttcggggag atggcttata
    45121 acatttctta cctgaccagg gtaccgggaa ccaacacctt actggcgtgt tgctgtcatt
    45181 taagaccaga agaggttaac agtgaatatt gaagagttaa aaaaacaagc cgaaacggaa
    45241 atcgctgact ttatcgcgca aaaaatcgcc gagctgaaca agaatacagg gaaagaagtc
    45301 tctgaaattc gcttcaccgc acgagaaaaa atgaccgggc ttgaaagtta tgatgtcaaa
    45361 atcaaaataa tgtgattttg tgaacatcac cccgtgcgag gtgatgttcc gcttgttgct
    45421 aatttagtga ccaatcattg gcgcttgcgg aattaagcgt cggtacaatt cctgcggcac
    45481 cgggctttgc catactcccg catacattgc gtaaccaatc accgcaaaca taatccccag
    45541 aaccagtagc gtcattaacc agccagacaa cgcaaaggct tttttatttg ccgcaggttt
    45601 ttgcagtgaa aaggttaatg ttgaggctac cggacatgac tctacgcaag tcatacagcc
    45661 ggtacattcc actgttcgta cctgaattaa tttatcgacc gggatccgtg atgggcaatt
    45721 ttttgcgcat ttgccacagt cgatacaact ttcggcattg cgacgaatct taaacggcga
    45781 taatagcgaa accatgccca tcagcgcgcc atatgggcaa agataacgac accaggcatg
    45841 gcgaataaac aggctggcaa tcagcaaaac ggtcacgctg attaatgtcg cggtccccat
    45901 atgacgaaag aaatcgagca ttttaacgtc catcaccacg ctgtagggcg acaacataaa
    45961 atagtgaatc gcctgagcgg gcatcaataa cgcgatatag agaaaaaaac tcaacagcaa
    46021 atacttcacg ccgcgcagag gaatatccag ccagcgggga aggacacatt gccgaccaaa
    46081 cagtttgtta ccgagatcgc cgattaattc agaaagcgta ccaaccgggc ataaccatga
    46141 gcaaaaggcc tttttgagta atagactgat gacgataaaa gcgaccaata acagcatcgc
    46201 ggcggcgtgg acggacggta actgacctgt tgcaaggcta tatttcagat tcatcagacc
    46261 ggcaatcggt agccagcctt cgatacctcc cggtctggcg acaaatgtcg tactacctgc
    46321 cgtttcgtaa tagcgcaccc aataccagaa cgtgatggca atataaatat tcattgccaa
    46381 cagtaataat tgcgtcgctt tacgccaggt cgtggcattg cgccagtcat tccacggtaa
    46441 tttgccgccc gtcgtgcctg gccgccgctg ccagcgggtt ctttttttct ctgccatgat
    46501 tttgccagtc cgttaagttg cataccaaat gccactattc tagttgttct taactggctg
    46561 atattgattc aaatcgcgtt caggtctttc ttattaacca tgcttccaga gcggcaacac
    46621 tgcgtgtaat ttcttcgtgt ggaagggggg cagataatgg ctgctgctcc agttgtgcgc
    46681 aaagctggct ggcgctacgc attcccagac tcgagcaact gctttttagc tgatgtgcgg
    46741 cacgctttat tttttcgctg ttctggctgg cgcgggcaat gtcgatttca tcgagaagcg
    46801 gcagggcatg ttgtttaaat aatatcagcc attcgtggat cttctccgtc cccatcaact
    46861 gagcatcttc attgagttgc gatacatcca gcggttgatc gttattgact tgtagttgga
    46921 gatagtgcgc cagtaactga ccgagcactt cacgcggcac cggtttaggg ataatcccgc
    46981 gaaataatga actggtacgc tggcgcaacg tttcgtcgat gacatgagcg ctaaagccaa
    47041 tcaaaaccag cgacggatat tgctgtgcca gttgccgggc aagcgtgatg ccgtcgatat
    47101 cgggcagatc aaaatccacc agtgcggcag caaacggttc actattttgc aacgtctcta
    47161 tcgcgtgcgc ggcatttcct accgcaacga cctgcgcacc actggtagtc agcatctcga
    47221 cggtaattcg ctgggttagc gggttatctt caattaacag caaacgtaaa ccgtccagac
    47281 gcaccgcctg attgactgtt tttggcacgg gagcagtggc aacacgtaac ggcaagcgta
    47341 aacaaaaaca gcttccaact tccggcgtgc tggtggcgct cagttcgccg cccatcgcct
    47401 gggccagacg gctactgata gtcagcccca gcccggtgcc gccgcgtttg ccgcttacct
    47461 gcacaaatgg ctggaagatt tctgccagtt tcgcgggatc aataccgcag ccgctgtctt
    47521 ccacttcgac cagccattgc tcgccatcag tgcggctacg taaaacgatc tgcccttcgt
    47581 cagtaaaacg cagggcgttg ctcaacaggt tggttataac ctgacgaata cgtcgcggat
    47641 cgcccattaa cgcggtcggt acatcgtcgg caattgctgt tgccaggtga atcgggcgac
    47701 ctttaacccg tccgctcatt aattgcaggg tactttccag cagcgggcgc ggttcaaagg
    47761 gctcatcgct gaccgaaaca ttcttgccac ccgcttcgat agccgaataa tcgagaatat
    47821 cgttgaggat ggtcagcaac gattcaccag agtcggtaat tgcccgcaaa tcatcacgct
    47881 gggcattaag tgcggggtta tctgccagca gttgcgcggt gccaagaata ccgtacagcg
    47941 gtgtgcggat ctcatggctc atcgccgcca gaaacgccga ttttgcctgg ctggcttttt
    48001 ctgcttccgc ccgtgcctgt cggtgttcta tcaccagttc ctgcaattca gctgtacgcg
    48061 ctttgacctg cgccgccagc tgttcacggt ggcgattcag tgcatgaaca ctgctgcgaa
    48121 acgcatccat cagccgcccg atggtgtcca gctcccgcac gccagcggtt tccgggaaag
    48181 gggagttgat atcaccgtcc agcagccgtt gcagcgcctg cgtttgttcg gcaagtggac
    48241 gcgtgactga gcgataaacc acgcgccaga ggatcagaat cagtgcgcaa agtgaaacca
    48301 tccccagcaa taacaggctg tattgcccgc gtgcactggc tttttccaga tgcgccagtc
    48361 cgtgctgatt acgcagctca atggtgtcga ccagctgact gacttcgcta ctaaactgcg
    48421 cgaactgggc gatgttattt tgggcgagag tttgcaggcg attgctgatt tcactgtcct
    48481 gctgatacag cgccagcaaa tcgctatatt ggctaacggt agttaacgtt gttgcgacct
    48541 gagcacgaac tcccggatct tcaatgcgta tttgccgacg ttgcagaatt ttcaccgcat
    48601 tattgagctg gtgttccagc gttgctgcat ttttctggat ctgctccagc ccaagattca
    48661 tcaccatttg ctgcacccgc agggcgctaa ggcgcagttc attcatctgg ttaacatact
    48721 caagatcgat atcaatcagc cgatcgagtg cactttctgc ggcctgacgc tgatgttgtt
    48781 cgatcaaatc gtaaatcccg gcctgggtcg ctccggcgga agttgccgca ttattcgcct
    48841 gaccttgcgc caggcgtgcg atttcatcgg cggcggcgac tatctgctga ctgagtcgct
    48901 gttgttgctg gcgcagttgc aaacgctgcc ccaccagttc cccttgctga cgtaacgaac
    48961 gggagatctc ctgctcctgt tgttcaatag cggtggtatc aaaaccttgt tcccgtaacg
    49021 cttgcagcaa cgcattaatc ttcaggcttt gtgcggtgag cattcgcccc tgcgcctgcc
    49081 acatcttttc gttatcggca ctggtcaggt tctgcgcggc gaaaagttcc caggcgctgg
    49141 cttcgctcaa ctggcgcgcc atattcatgg taggaatcaa tgcctgagtg ttgtcttttt
    49201 ccacttggct gataaagcgc aggttgtacc atcccaccag ggtactggtc agggttaaca
    49261 gcgccatcag ggcaaagccc atccagagtc ttcgggtcag ggttaaattc acggtcggtg
    49321 cacttaagat gaaaaaggtt gagtcgcaaa gcggaatgca tctagcataa agccttatta
    49381 ttgatgaggc tatcatgcgc gtactgctat tgttacttct ttcccttttc atgttatcgg
    49441 cattttcggc tgataacctg ttgcgctggc atgatgcgca gcatttctcg gtgcaaccct
    49501 ctacgccgct taaaaccaaa cgtgcatgga aactgtgcgc gctttatccc agcctgaaag
    49561 attcatactg gttatcgttg aactatggta tgcaggaggc tgctcgccgc tacggtgtgg
    49621 atttaaaagt gctggaggca ggcggctaca gccagttggc tacccagcaa gcacaaatcg
    49681 accagtgtaa acagtggggc gcagaggcca ttttgctcgg tagtagcacg acgtcatttc
    49741 ccgacctgca aaagcaggta gcaagtctgc cggtgatcga actggtaaat gctattgatg
    49801 ctccccaggt gaaaagccgc gttggtgtac cctggtttca gatgggctat caaccaggac
    49861 gatatctggt gcaatgggcg cacggtaaac cactgaacgt gctgttgatg cccggacccg
    49921 ataacgccgg gggcagtaag gagatggtcg agggttttcg cgcagccatt gccggaagcc
    49981 cggtacgtat tgttgatatt gcgcttggcg ataacgatat tgaaatccag cgtaacctgt
    50041 tgcaggagat gctggagcgc catccagaaa tcgacgtcgt tgccggaacg gccattgcgg
    50101 cagaggcggc aatgggggaa gggcgtaacc tgaaaacacc gcttaccgtg gtgtcgtttt
    50161 atctttcaca tcaggtgtat cgcgggctga agcggggaag agtgattatg gctgccagcg
    50221 atcaaatggt ctggcagggg gaactggcgg ttgagcaggc catcaggcaa ttacaggggc
    50281 aatcggtgtc tgataatgtc agcccaccga ttttagttct gacgccgaaa aatgccgacc
    50341 gcgaacatat ccgccgctcg ctgtcaccgg ggggatttcg tccggtctat tattatcagc
    50401 acacatcagc ggctaagaaa taaccttcgc catgttgtgt caccagtaaa tccgcgctga
    50461 gtttatggcg taaacgacga attaacacat cgacggtgcg caggtcaggg ttttccaccc
    50521 gacgcgcaga gagcatacgc agcagacgtt cacggctaag aatttcgccc ggattcgtca
    50581 caaatgccac caacatttca tactctgcgc gggtcagttt aatcggctcg ccatctcgtt
    50641 ccagcgtatg gcgcgacaca ttcaggcaat aaccggcaaa gcgatagcag ttgtcctgag
    50701 tgtgcggttg agcttgtcgc gcgaggtcga ttcgccagag cagatttttc acccgtacta
    50761 ccagttcgcg cagttccagc ggtttggtga cgtaatcgtc tgcgcccatt tccagtccaa
    50821 caatacggtc aatccgatcg ctgcgtccgg taaccagaat aatccccacc gttgagcgtt
    50881 ctcgcagggc gcgggttaac atcaggccat tttcatcggg caaattgata tccagcagaa
    50941 ttaaatccac cgactgattc tgcataattt cccgcagccc ggcaccgctc gccgtaacgg
    51001 aaacggtata cccctcctga gtgaagtagg attgtaatcg cgcctgggta accggctcat
    51061 cttcaacaat aacaatgtga tgtggcatca gagggtttta ctcattctgt tcatatctgt
    51121 tcatattctg ccgtaagccg ttcatcctga ccagtgccgc tgttcatatt tactcattaa
    51181 gatcgcttca ctaaaccata attttacagg ggctattatg cggaaactct ggaacgcgct
    51241 acgccgaccc agtgctcgtt ggtcggtact ggcgctggtc gctactggga ttgtgattgg
    51301 cattgcgctg attgtattgc cacacgttgg gatcaaagtc accagcacaa ccgaattttg
    51361 tgtcagttgc cacagtatgc aaccggtgta tgaagaatat aaacagtcgg tgcatttcca
    51421 gaacgcctcc ggcgtgcgag ctgaatgcca tgactgtcat atcccgccgg atattccagg
    51481 catggtgaag cgcaaactgg aagcgagcaa cgacatttac cagaccttta ttgcccactc
    51541 cattgataca ccagagaaat ttgaagccaa acgcgcggaa cttgccgagc gtgaatgggc
    51601 gcgaatgaaa gaaaacaact cggcaacctg ccgctcctgc cataactacg atgcgatgga
    51661 ccatgcgaag cagcatcctg aagcggcgcg tcagatgaag gtggcagcga aagataatca
    51721 atcctgcatc gactgtcata aaggtattgc ccaccagtta ccggatatga gtagtggctt
    51781 ccgtaagcag ttcgatgagc tgcgcgccag tgctaatgat agtggtgaca cgctgtactc
    51841 cattgatatt aagccgattt atgcggcgaa aggcgataaa gaagcctctg gttctctgct
    51901 gcctgcttcg gcagtgaaag tcattaaacg tgacggcgac tggctgcaaa ttgaaatcac
    51961 tggctggacg gaaagtgcag gacgtcagcg tgtactcacc caattcccag gtaaacgcat
    52021 ctttgttgcc tcgattcgtg gtgatgtgca gcagcaggtg aaaacgctgg agaaaaccac
    52081 cgttgccgac accaataccg agtggagcaa gttgcaagcc actgcgtgga tgaagaaagg
    52141 cgacatggta aacgatatca aaccgatctg ggcttatgcg gattcgttgt acaacggcac
    52201 ctgtaaccag tgccacggcg caccggaaat ctctcacttt gacgctaacg gctggatcgg
    52261 cacgctcaac ggcatgattg gctttaccag cctcgataaa cgtgaagaac gcaccttgtt
    52321 gaaatatctg caaatgaatg cgtctgatac cgcaggtaag gctcacggcg ataagaagga
    52381 agaaaaataa tgaacaataa cgatctcttt caggcatcac gtcggcgttt tctggcacaa
    52441 ctcggcggct taaccgtcgc cgggatgctg gggccgtcat tgttaacgcc gcgccgtgcg
    52501 actgcggcgc aagcggcgac tgaggctgtc atctcgaaag agggcattct taccgggtcg
    52561 cactgggggg ctatccgcgc gacggtgaag gatggtcgct ttgtggcggc aaaaccgttc
    52621 gaactggata aatatccgtc gaaaatgatc gccggattgc cggatcacgt acacaacgcg
    52681 gcgcgtattc gttatccgat ggtacgcgtg gactggctac gtaagcgcca tctgagcgac
    52741 acctcccagc gcggtgataa ccgttttgtg cgcgtgagct gggatgaagc cctcgacatg
    52801 ttctatgaag aactggaacg cgtacagaaa actcacgggc cgagtgcctt gctgaccgcc
    52861 agtggttggc aatcgacggg gatgttccat aacgcttcgg ggatgctggc gaaagctatt
    52921 gccttgcatg gtaatagcgt tggtacgggc ggagattact ctaccggtgc tgcgcaggtg
    52981 atcctgccgc gcgtggttgg ctcaatggaa gtgtatgaac agcaaacctc ctggccgctg
    53041 gtattgcaga acagcaaaac cattgtgctg tggggctctg atttgctgaa aaaccagcaa
    53101 gcgaactggt ggtgcccgga tcacgatgtt tatgaatatt acgagcagct aaaagcgaaa
    53161 gtcgccgccg gtgaaattga ggtcatcagc atcgatccgg ttgtcacatc cacccatgag
    53221 tatctggggc gcgagcatgt gaagcacatt gcggttaacc cgcaaactga cgtgccgctg
    53281 caactggcgc tggcgtatac gctgtacagt gaaaacctgt acgacaaaaa cttcctcgct
    53341 aactactgtg taggttttga gcagttcctg ccgtatctgc tgggtgagaa agacggtcag
    53401 ccgaaagatg ccgcatgggc tgaaaaactg accggcattg atgccgaaac cattcgtggg
    53461 atggcgcggc agatggcggc gaacagaacg caaattattg ctggctggtg cgtgcagcgt
    53521 atgcagcacg gtgaacagtg ggcgtggatg attgtcgttc tggcggcgat gctggggcaa
    53581 attggcctgc caggtggtgg ttttggtttt agctggcact ataacggcgc aggcacgccg
    53641 gggcgtaaag gcgttattct gagtggtttc tccggctcta cgtcgactcc gcctgttcac
    53701 gacaacagtg actacaaagg ctacagcagc accattccga ttgcccgttt tatcgatgcg
    53761 atcctcgaac cggggaaagt gatcaactgg aacggtaaat cggtaaaact gccgccgctg
    53821 aaaatgtgta tttttgccgg aactaacccg ttccatcgcc atcagcagat caaccgcatt
    53881 attgaaggct ggcgcaagct ggaaacggtt atcgccatag ataaccagtg gacctcaacc
    53941 tgccgctttg ccgatatcgt actgcctgcg accacgcagt ttgagcgtaa cgatctcgac
    54001 cagtacggta accactctaa ccgtggcatt atcgccatga aacaggtcgt gccgccgcag
    54061 tttgaggcgc gcaacgactt tgatattttc cgcgagctgt gccgtcgctt taatcgcgaa
    54121 gaagccttta ccgaagggct ggacgaaatg ggctggctga aacgcatctg gcaggaaggt
    54181 gtacaacagg gcaaaggacg cggcgttcat ctgccagcgt ttgatgactt ctggaataac
    54241 aaagagtatg tcgagtttga ccatccgcag atgtttgttc gccaccaggc attccgcgaa
    54301 gatccggatc tcgaaccgct gggcacgccg agtggcctga ttgagatcta ctcgaaaacc
    54361 atcgccgata tgaactacga cgattgtcag gggcatccga tgtggtttga gaaaatcgaa
    54421 cgctcccacg gcgggcccgg ctcgcagaag tatccgttgc atctgcaatc tgtgcatccg
    54481 gatttccgac ttcactcgca gttatgtgaa tcagaaacgt tgcgtcagca atatacggta
    54541 gcgggcaaag agccagtgtt cattaacccg caggatgcca gcgcgcgcgg tattcgtaac
    54601 ggtgatgtgg tacgcgtctt taacgctcgt ggccaggtgt tggctggagc agtggtttct
    54661 gaccgctatg cacccggcgt ggcgcgaatt catgaagggg catggtacga tccagataaa
    54721 ggtggcgagc ctggtgcgct gtgcaaatac ggtaacccca acgtgttgac catcgacatc
    54781 ggtacttcgc agctggcgca ggcgaccagt gcacacacta cgctggtgga aattgaaaaa
    54841 tacagcggga cagtggagca ggtaacggcg tttaacggcc ccgttgagat ggtggcgcag
    54901 tgcgaatatg ttcccgcgtc gcaggtgaaa tcatgaccac gctgacagca ccacagattg
    54961 cctgtgttta cgcctggctg gcgcagttgt tctcccgtga actggacgat gaacaactga
    55021 cgcagatcgc cagtgcgcag atggctgaat ggttttcttt gctgaaaagt gaaccgccgc
    55081 tcacagcggc ggtgaatgag ctggaaaacc gtattgcagc cctgaccgta cgtgacgatg
    55141 cccgtctgga actggccgct gacttttgcg gcctgtttct gatgaccgac aaacaagctg
    55201 cgctgccgta tgcatcggcc tacaaacagg acgagcaaga gattaaacgc ttgttagttg
    55261 aggcagggat ggaaaccagc ggcaatttca acgaaccggc agatcatctg gcgatctatc
    55321 tcgagttgtt gagtcatctg catttttcgc tgggagaggg gagcgttcct gcgcgaagaa
    55381 tcgacagttt gcggcaaaaa acactgacgg cactgtggga atggttacca gagtttgctg
    55441 cgcgttgtcg tcagtatgat agctttggtt tttacgcggc actaagccag ttattgctgg
    55501 tgttagtgga gtgcgaccac caaaacagat aacgtcgttt gtaggcctga taagacgcgg
    55561 caggcgtcgc atcaggcatt agtgcgcagt tgccggatgc ggcataaacg ccttatccgg
    55621 cccacaggaa cagtaatctt tgtagaccgg ctaagatgcg tcatcacatc cggcaaacac
    55681 acatcacggg tgagccacaa accgggaaag ccgctggcgc agcaggcggt tttcctgctt
    55741 caggtgcgca atatcatcca ttaacgtcag cgccaccgcg atccccggcc agtccagagc
    55801 cagttcatga cgtagacgta ccgcgcgttg caccacaatg gcggcatggt cgtcaaatac
    55861 ccaggttgtt tcctggatct cacgcggttc aaccaccccc aaaccgacaa tttcattcaa
    55921 ctcctcttca gagatgccgg tatgcaggca aaattcggta atagtaaaag tcaccgtaac
    55981 attagccatt atgctttccc ccaatcttta cgtggatcaa aagacgactg ggcgtctgcc
    56041 agttgctgcc acagcgcggc agtgttttca tccggtttcg gcggcatcac gattttcagt
    56101 accgcataca gatcgccggt ctgttttttg ctcaccagac ctttgccttt aacgcgcaat
    56161 cgttgcccgg cctggctgcc aggcgggata gtcagcaaaa tgctttcttt cagtgttgga
    56221 acggtgactt tagcacccag cgccgcttcc cacgggctaa ccggcaccac aatttccaga
    56281 tcctggccga caatatcaaa cagcggatgt ggcgcaatat gaatcaccag ccacaaatcg
    56341 ccatttggac cgccgttttc gcccggcgtc ccctggcctt tcaggcggat acgttgacca
    56401 ttgccgaccc ctgccgggat cttcacattc agcgttttcg ggatttcctg ttcgatcatg
    56461 ccaaaggcgt tataaaccgg caggttatag ctgatggtac gcttatgctc agtaagcgtt
    56521 tcttcgagga ataccgccac ttcgatttca atatcgtggc cgcgagtggc ggggcgttga
    56581 cggctctggc gggcatgctg accgaaaatt gacgagaaaa tatcgtcaaa atcttcggcg
    56641 ttaaaactct gactgtcgcc atgctggaac tgacggctaa attgtggatc gttgcgatgt
    56701 tgccacatct gatcatactc agcgcgacgt tgttcatcac tcaacacttc ccaggcttca
    56761 gcgacctctt tgaagcgggc ttcggcatcc ggttctttgc tgacatcagg atggtatttg
    56821 cgggccagtc gacgataggc ggtcttgatt gtcttgagat cgtccgtcgg tttcacgccc
    56881 atgatggcgt aataatcctt taattccata gcgttatctc gcgtaaatca acacaaattg
    56941 aaggaacccc tgtaaggtaa ctcctataag tgtagggtaa tcctcaaaat ttcatatgcc
    57001 aacacagaat atgttattga aatcatcgcg gagaggaggt cgcctcaagg tggggtgctg
    57061 aacatatttt aaacaggtga aaaagggtga gcgatttttg atagttgaac caggcacgtt
    57121 aagttttact agtgcgtcat tatttattaa attttatagg cgctatatat gggtagtaat
    57181 atacatggaa ttagttgcac tgcaaataat tatttgaaac aagcctggca caatataaaa
    57241 aaagagcacg aaaaaaatca aacatattca atcacgcttt ttgaaaacac actggtgtgt
    57301 tttatgcggt tgtataaaga aatcagacgt caaaaagctg aagactacat tccatgcctg
    57361 gaatgcgaat cactagaaaa agaatttgag gaaatgcaga atgataatga tctatcatta
    57421 tttatgagaa cattgcgtac taatggtacg gaaatttatt caggggtttc aggaggtatt
    57481 acatatacta tacaatatgt tcgagatatt gatattgtta gagtgtcctt gccgggcaga
    57541 gcttcagagt ctatcacaga ttttaaaggt tattattggt atggctttat ggaatatatt
    57601 gaaaacatta atgcgtgtga tgatgttttt tctgagtgtt gtttagaaga tgaaaatata
    57661 agtgtccagc caaaacagat acatacgccg ggaatatcta atttagatgc tggtattaat
    57721 ttgtctggta tatcttttat tcagagtgaa attaataaaa cttatgaatt aaaatacgct
    57781 ccagtagatg gcgatggata ttgtctgtta agagccatac tggttttaaa acaacatgat
    57841 tattcatggg cgctgggcag tcataagacg caaaaggaag tatacgaaga gtttattaaa
    57901 attgttgata aaccaacaat cgaggctctt gttgatgctg cattttgtga tctcagggaa
    57961 gatgttaaga cattatttgg cgttgatctg caatctgaca acaaaattca gggtgtgggt
    58021 agtcatatgt catggagctt tctgtttttt aaaaaacaat tcattgatag ttgcttgaat
    58081 aacgaaaaat gtatcctgca tttacccgag tttatattta aagataacaa gaagttgctt
    58141 gctttagata ccgacgcttc ggataggatt aaagcggtga agaattttct tgctgttctt
    58201 tcagatagca tttgctcatc gtttattgtt accagtaatg tggcatcaat ctccttgggg
    58261 aacgaatcat tttcaacaga tgaagacctt gagtgtggtt atttaatgaa tactggcaat
    58321 cattatgacg tttacctccc tcctgaactt tttgctcagg cttacaagtt aaacaataag
    58381 gaaaggaatg cgcaacttga ctatttaaat cgttatgtaa tttaatggca aaggcatatg
    58441 ctaaaaacca ttgttattag tctcacactt ttttattggt aaatattgtc tctgtattgg
    58501 aaacgccgca gatattctgt ttagccacag gtgcaattat cagcggcgta cgcgaggcag
    58561 gggctaatca ggcatagttt gcgtcaaacc ttgcctgttt ttgaagatgt atatagaaaa
    58621 acaggcgttc aacaagccat tttgcgaacc tgttcccgga aaaaagtcat atttctgtca
    58681 cactctttag tgattgataa caaaagaggt gccaggaatg aacaaaacgc taatcgccgc
    58741 aactgtggca gggatagttt tactcgcttc aaatgctcag gcacaaaccg taccggaagg
    58801 ctatcagcta cagcaagtgc tcatgatgag ccgccataac ttacgtgcgc cgctggcgaa
    58861 caatggcagt gtgctggagc agtcgacgcc gaataaatgg ccagaatggg acgtccccgg
    58921 tgggcaactc accaccaaag gtggcgtgct cgaagtgtat atgggccatt acatgcgtga
    58981 atggctggca gaacagggga tggtgaaatc gggggaatgc ccgccgccgg acaccgttta
    59041 tgcctatgcc aatagtctgc aacgtaccgt tgcgactgca cagttcttta ttaccggcgc
    59101 attcccgggg tgtgatattc ctgtgcatca ccaggaaaaa atgggcacta tggacccaac
    59161 ctttaatccg gtgatcaccg atgattccgc cgcattcagt gaacaggcgg tggcggcaat
    59221 ggagaaagag ctcagcaaac tccagcttac cgacagctac cagctactgg aaaaaatcgt
    59281 taactataaa gattcccctg cctgtaaaga gaaacaacag tgttcgctgg tggatggcaa
    59341 aaataccttt agcgcgaagt atcaacaaga accaggtgtt tccgggccgc tgaaagtcgg
    59401 caactcgctg gtagatgcgt ttactttgca atactacgaa ggttttccga tggatcaggt
    59461 ggcctgggga gaaatcaaat ctgaccagca gtggaaggtg ttgtcgaagc tgaaaaacgg
    59521 ttaccaggac agcctgttta cctcaccgga agtggcgcgc aatgttgcga aaccgctggt
    59581 cagttatatc gacaaagccc tggtcaccga tcgcaccagc gctccgaaaa tcacggtgtt
    59641 agttgggcat gactccaaca ttgcctctct gttaacggcg ctggatttca aaccgtatca
    59701 gttgcatgac cagaacgaac gcacgccgat tggcggcaaa atcgttttcc agcgttggca
    59761 tgacagcaaa accaatcgcg acctgatgaa aatcgagtat gtgtaccaga gtgcagaaca
    59821 gttacgtaat gctgacgcgt taacccttca ggcacctgcg cagcgcgtga cgctggaatt
    59881 aagcggttgt ccgatagata ccaacggttt ctgcccaatg gataagtttg atagcgtgtt
    59941 gaatgaagcg gtgaaataac agaaaactcc cccgttcgct acgggggagt cgctggttaa
    60001 acgtttttac gttcgatggt ctgttcgccc caaaaaagcg aatctttgtc ggtcttagca
    60061 aaggctttga ctaacacttc atcgctacct tcttcccaaa tcttttccgc cattttttcg
    60121 tcgtacccgg cgacttcgaa aatggcctcg gctatttccg gcgacgtatt gcgcagagat
    60181 gcccattcac cgacgtgatg agctttcgct tcttgagttg gcatgcgtat cctcctgttg
    60241 aagattagcc gttaagttta actgccagac ctgcgacata ttccccttga taacgagcaa
    60301 tagacagttc ttcctggctg ggctggcgtg aaccgtcacc gcctgcgatg gtggttgcgc
    60361 cgtacggcgt accgccgcga acctgtgaaa cgtcaaataa ttcctgcgct gcgtagccaa
    60421 tggggacaat caccatgccg tgatgcgcaa gggtcgtcca ggtggatgtg atggtttgtt
    60481 cctgaccgcc gccagtaccg gtggaactaa agacgctcgc cagttttccg tatagtgcgc
    60541 cggaagccca caggccgccc gtctggtcga ggaaggtacg catttgaccg gacatgttgc
    60601 caaagcgggt aggtgtacca aaaataatgg catcgtaatc ggccagttct tgcggggttg
    60661 caaccggtgc agtttgcgtt ttaccgcctg ctttttcaaa taattgcggc ggcatggttt
    60721 ccggtacacg cttaacgaca acttctgcgc catccacttt gtttgcaccc tcagcgactg
    60781 cgcgtgccat cgtttcaata tgtccgtaca tggaataata aagcaccaga actttagcca
    60841 tttctaacca ctcctcgtgt tatctctatt ccgtagcgat tcgctaccac ttatttaaag
    60901 ataagacgtc cttttcagag tgcaaatttc acaaccactt atttgattta taacaacttt
    60961 cacaagcacg taattttgtc gcaaaatgac acatttttat ctcatcgcgt ttttttaatc
    61021 ataagagcgg cttatggata attattggag atgatatcta ttctcgctaa gaagctgttg
    61081 caggatatta ccaaacgcgg gtctgcccac gtcagttcac taagcttagt cccacgtagc
    61141 gaaaatatgg cagccgccat acgccgcgtt aattctatgc aatatgatgt ctatacccag
    61201 acggaggtca gtaatggcaa accatcgagg cggttccggc aattttgcag aagaccgcga
    61261 aagagcatca gaagcaggta aaaaaggtgg acagcacagc gggggtaatt tcaagaatga
    61321 cccgcagcgc gcatctgaag caggtaaaaa aggtggcaag agcagtcacg gcaaaagcga
    61381 caactagccg ggctaatcaa tgacgaatgc atttttttct taagctcgtc aaaaagccat
    61441 caccgccggt aaccccggcg gttttctgtt tatggctcct gatgaataac ttctggcggt
    61501 ggaacgtcaa ccaaccttct gcttaataac gcattgagta aaatcgcgcc aaaggttgct
    61561 gtaccgatcc ctcccaacgt aaaaccgccc agcgtgagag caaaatcacc cgcgcccagc
    61621 actaaggtta ctgcgaccat aatcaaatta ccgttctggc ttaaatcgac acggttttgt
    61681 acccagatcc ttgcgcctgc gacggcaatc agcccgaaca caacaattga tgcaccacca
    61741 atcaccgcgg ccggaatggt atggatcagc gcgccaaatt tcggcgaaaa gcccaacagc
    61801 atggcgatga cggcagcagc aacaaacacc agcgtcgagt agactttggt cacggccatc
    61861 acaccgatat tttcagcata ggtggtgacg ccgctaccgc cgacagagcc ggaaagcatc
    61921 gttgccagac catcaccgac gaatgcccgt cccatatacg gatccatatt gcgtccggtc
    61981 atcccggcga ccgccttgag atggcctaag ttttccgcca ccagaatcac cgccacgggc
    62041 gcaatcagca tcattgcctg accattaaaa gcaggagtgg aaaaatgtgg caaaccgaac
    62101 caggcagcat ggctgacgag agtaaaatcg acggcttttc ccagccctaa aacgttggtc
    62161 atcacgccat acagcagaca ggcgacaatt aatcctacga gaatcaataa ccgctggatc
    62221 atgccacggg taaataccgc taccagccca atacacagca ccgtcattac cgccatccag
    62281 ctatcaaagg ccgaagccga tacacttttc actgcgatag gcgctaagtt caggccaatc
    62341 gccatcacca ccgcacccgt caccaccggc ggcattagcc gttcaatcca gcgcgtaccg
    62401 attttcatca ccaccaggcc aatgacggta taaaccagcc cacaggcgat aatcccgccc
    62461 agcgcgatgc tgatattcgg gttaatgccc tgaccgttaa agcccgtcgc ggcaatcacc
    62521 acgccgacaa aagccgcgct ggagccgaga taactgggga cgcgcccgcc ggtaataaag
    62581 aaaaacagta acgtgccgat ccccgacatc aaaatggaaa gattgggatc cagccccatc
    62641 agaataggca ttaacaccgt cgcgccaaac atcgccaccg cgtgttgaac gcccattact
    62701 gccgtctgag caaacggcaa tcgttcatcc ggcgcgacca cgccgctctc tgtagaggtc
    62761 gattttaact gccagtgagg aaaaccgaac attgccatca gctgtctcct taaggaggtt
    62821 aacaagcagg gcgcatcagc gcgtgataac tgcgatcaaa ccacaccagc ccgtaggggg
    62881 tggcgtgacg atgaatcgct tcgatggcgc aaaacagaat gtcgtgggtg ccgacgctca
    62941 ccacctggct gatacggcag tcaaacgaaa ccagtgcttc ttccagttgc gggcatccgg
    63001 tcacaccagt ctgccagcgg gcggcggcaa agcggtgttc catgggcgtt ttgccgccaa
    63061 aaaggtttga aagcagctcc tgcccggcgc taagtgtatt tacacacagc gttcgatttt
    63121 cattgaatac cgaccagacg gacgccccac gattcaggca caccagtaat gtgggcggcg
    63181 tatcggtcac gctgcagacg gcgctggcgg tgaacccggc gcgcccggct ggaccgtccg
    63241 tggtgatgat attgaccgcc gcgcccatgc aggacatcgc atcgcgaaaa gtttgttgat
    63301 cgacaatgtt catagtttgc tccttacaac agcccgcagg cttcttcaaa ggacagacgt
    63361 ggcaggcgcg caaaaagttt gctggaatcg ccatagccga tattaatcag cagattgctc
    63421 ttcagcgtgc tgcccgcaaa aaaggcgtcg tcaacgtatt gacggtcaaa gcccgacatc
    63481 gggccggtat ccagcccgag cgcacggcag gcgacgatca gataggccgc ctgcatggaa
    63541 ctgttgcgaa acgctgtttc ttcggcaagt tgtgggctgg aggtaaacca actgcgggca
    63601 tcgccgtgag gaaacagctg tggtaaccgt tcataaaatt cactgtccca ggcgacgata
    63661 gcggtgacgg gcgcggtcag ggttttttgc agattgccgc tggaaagcgc cgggcgcaga
    63721 cgttcttttc cttctggagt gcggataaac acgatccgtg ccggagaaca gttagctgat
    63781 gtcggccccc atttcatcag ggcataaatc tcccgtaacg tctcatcgct gacgggtgtc
    63841 tcccgccagc cgttgtgagt gcgggcatcg gtgaacaggg tgctaagcgc acctgggcta
    63901 acggcttcgt tcatagcaat tccttacagg gcggcttcac ggtgatgtaa caggctggca
    63961 agcccgttga gtaacagagc attaaacgtt tcgggatcgg tcacgttgca ggcgtgtccg
    64021 ccatagcgca tcaccatttt ctggctatcg ggcagggcgg catgaagttc actggaacat
    64081 gctgttggca ccagaagatc atcactggcg cagatgattt gtaccgggca gcggatacga
    64141 tccgcatggt gactaaagtc agcgcgtttg agggcgttaa gtcgacgcag taaattattt
    64201 ttgccctgaa aatgcgccag tgccagcgca tcttctgcct caaggcgagg tgcgcgggcc
    64261 gccatccagt cggcgggata gaggaacaat ggctgagctg ccacccatgc ctgcgcgccg
    64321 ccgctatgta gtaactgttc gcgaacctga aaacagcggc gcgtatgggc gtttattcgt
    64381 agccagccgt taacgctgac cagcacagtt accgacgcgg gataatccag cgccagctgc
    64441 attcccacca gcgcaccgag cgcatggccg accaccgcgt aacgctcaat ccctgcggct
    64501 accagcgcct gatgcagttc cgctgccatc tgggcgatac tgtaatcttc tgccagcgtg
    64561 tcgggattat tgccggtgcc gcgctggtcg taacagacta cctgatactc ctgctccagc
    64621 accgccagtt gcggtaacca gtaactgccg ctaccgccaa gacccgaaat caacaccact
    64681 acgggcgcat cagcataagg gggaggtgag agtgaaagtt tcatcgcgac ctcacttggc
    64741 gatatgcgca attgtggcga tttccaccag cgcgtcaggt tttaccagtc cgcactgaat
    64801 gcagaatcgc gccggtttgt cacccgggaa aaactcggcg tagatttcgt taatcgcggc
    64861 gtaatttttc cagtcggtaa taaagatgct gttgaaggtc acatccgcca tcgagccacc
    64921 cgccgtctcg atcaccttgc ggatgttttc cagaacgtgg cgggtttgcg cctttgggtc
    64981 atcggcaaac agcacgttat tatgttgatc aaaagccagc gtaccggaga catacaccac
    65041 gccatcagcc agcgtgccgg gaacgaaggg ggccagcggt gcgctgctgc cagcgggaat
    65101 aattacggat tttggcatcg ttaaactcct taagcgatac gagcaaagga cgtgggagaa
    65161 agcgcgtcgc agaacgtttc gacgtcgctg acccagccaa aaaaggtttc gatattgaat
    65221 aacgcggctt tctgtgcaaa ttccggcccc gcctggtgtg ttgcgtcttc caacaccacg
    65281 ccgaaatact ccagaaaaaa gccatcgcgt agcgtcgatt cgacgcagac gttggtagcg
    65341 ataccggtga aaaccagatg gcgtattcca cggctgcgca aaatgctgtc cagcggcgta
    65401 ttgaagaaac cgctgtagcg cggcttcggc agcacaatat cgccaggctg cggcaccagt
    65461 tcatccacca gttgataatc ccaggagcct ttcgccagca atttcccctg cagctgcggc
    65521 tgcttacgca tggttttcag ggcgttcgat ttatgaaaat tcggtgagcc ggggccgcca
    65581 gcctcgacat actgtgcatc ccagccattt tgaaaccaga tgatcagcat ccctgccgct
    65641 cgcgctgcgg tcacggcggt ttgaatgttg gcaatgaccg ggcgagtggt tgagacatca
    65701 aacccggcga gatctaagta gccgcctggc gtggcataag cgttttgcat atccaccacg
    65761 atcagcgcag tttgctgcgg atcgaaggta atggcttccg gtcgagcggt taaggtcgtc
    65821 atcatgccac ctcctgagtc agcgcaggga gatgggcgcg gcactgcatc agtggttgaa
    65881 tgcgctcgcc gaagttttcg attcccgaca gaaaatcatc gaaggtcaac agcacgcctt
    65941 cggcaccagg cacggttgcg acttcatcta acatgcgcgc gacactggcg taagaaccga
    66001 ctaacgtccc catattgatg tttaccgccg aagtgggatc ggccatctga cggacgttgg
    66061 tgtctgtacc ggagcgggta tctttctgac tttgttcggt tagccagctt aaggcctctt
    66121 catccgcgcc cgctttgtag tgttcccatt ttgcacgagc ggcatcgtcg gtttcgtcgg
    66181 caatcaccat aaacaacaca taagagccaa cgtcgcgccc ggtttgctct gcggcctgtt
    66241 tcatccgcgc agcggtcggg gcgaaagccg tgggtgtatt tacgcctttg ccgaaacaga
    66301 agttaaaatc ggcatactgg gcggagaacg ccatgccagc gtcgctttgc ccggcgcaga
    66361 tcactttcat gggtacgctc ggttgcggac tgacgcgaca atcattcatg gtgaaaaaat
    66421 cgcctttaaa atcgcttttg cccgtgcccc acaggtcgcg cagcacctga acatattcgg
    66481 tgagatagtc gtaacgacgg gagaaatagt catcgctagg ccagatcccc atctgctcat
    66541 actcgggctt ttgccagcca gtcacgaggt tgacgccaaa acgcccgcca gagatggagt
    66601 caatggttgc ggccatacgg gcgacgattg ccggaggtaa cgttaaggtg gcggcagtgg
    66661 cgtaaatctg aatccgcgag gtcacggctg ccagccccgc catcaaggtg aacgactcaa
    66721 ggttgtgatc ccagaactca gttttgccgc caaagccacg cagtttgatc atcgacaggg
    66781 cgaaatcgaa atggtagtgc tccgcttttt gcacaatggc tttattcagt tcaaaggtcg
    66841 gcatgtactg cggcgcgtgg gtcgaaatga gccagccgtt gttgccaata ggtacgaata
    66901 cgccaatttt catcatcaac ctctcttcgt ctcgtaaagt gaaagtcaga cggggcgctg
    66961 catcctgcat atccttttca gccgcgtaat ggcttgtttg caaagcggat gccagttttt
    67021 aaaaagcgaa tgttattaat gtgttaatgt ttggttgtct gaaatatctg gaaaaaagtg
    67081 gactaaacgg tcaaaacagt tgcacataaa acatgcatcc gtgcgcgatg agagtgcaga
    67141 aggtcgaggc cgggcggggg ttttgctatc ctgttgccaa tctacaagag gggagagcgc
    67201 atgacgcaag gcgcagtgaa aataacgggt aaacgttcgc gcgcagtaag cgcgaagaaa
    67261 aaagcgattc ttagcgcagc actggacact ttttcacaat tcggttttca cggcacaagg
    67321 ctggagcaga tcgcagagtt ggcaggcgtt tcaaaaacca atctgctgta ttacttcccg
    67381 tcaaaagagg cgctgtatat agccgtactg cggcagattc tcgatatctg gctggcaccg
    67441 ttaaaagcgt ttcgtgaaga tttcgccccg ctggcggcga tcaaagaata catccgtctg
    67501 aagctggaag tttcccgcga ttatccgcag gcttcgcgcc tgttctgtat ggagatgctg
    67561 gcaggcgcgc cgttgttaat ggatgaactg acgggcgatt tgaaggcatt aattgatgag
    67621 aaatccgcgc tgattgccgg ttgggtaaaa agcggcaaac tcgcgccgat tgacccgcag
    67681 catttgattt ttatgatttg ggcttccact caacattacg ccgatttcgc ccctcaggtg
    67741 gaggcggtga caggcgcgac gttgcgcgat gaggtatttt tcaatcaaac ggttgaaaac
    67801 gtgcagcgga ttattattga ggggattcga ccacgctaat gatgccggag gaggttgtaa
    67861 catcctccgg ctacctgttt aaccgatcgt cattaaacta gcgttaccgc cagcggcagc
    67921 ggtattcaca ctcagcgaac gttcgatata cagccgttcc agcaggatat tgctttcgcc
    67981 acgggcaaaa ccctgcaccg aaacaattgc gccatcccgc gcggcaacgg cttcacacaa
    68041 tgcgcgaagc tgatccgaat caccgtggaa gatcaccgca tcaaagggtt gagcggttat
    68101 attttccgct ttcgccagtt gaatacgttc gctgactgcg gatggcaatg ccttcactaa
    68161 ctgatgatgc agcgtgtcat ccggccacag tacctggctg cccaccgcca gcacggcggc
    68221 gagctgagtc agcgcatcct gttcatcatc cgcgatacac aatacgcgct cacgcggcag
    68281 cagcgtccag gtgttgcgtt cacccgtcgg ccctggcagc aatcgttgtg ttcctgcctg
    68341 cgccagctcg ccatattgcg tacataacgc ctgcaattct ggacgatttg ctgcccattc
    68401 ccgcagtgca tttagcggct gagtcaatgc ggctttcaac tgcgcatcga ccggatactc
    68461 tgcatcctga cgcgcgagcg tcaccgccag cgcactttcc gggcgattcg ccagcagacg
    68521 gtagagatag agtggaccgc ctgctttcgg cccggtgcca gacaaccctt cgccgccgaa
    68581 cggctgcacc ccaaccactg cgcccaccat attacggtta acatacaggt taccaacatg
    68641 cgccgagcca gtgacctggg cgatggtttc atcaatgcgc gtatggacgc caagcgtcag
    68701 accataaccg gaagcgttaa tctgctcgat cagcgccggc agctggttac ggttataacg
    68761 caccacatgc agcaccggac caaagacctc tttttgcaat tcggcaaaat catccagttc
    68821 gatcagcgtc ggagcgacaa aggtgccgct ttgccattca cgggtatctt cgctgttttc
    68881 ccgcaccggc tggaacacct gacggccttt actacgcatg gtctgaatat gacgctcgat
    68941 attggctttc gcttcgctat caatcaccgg accgatatcg gtggtcaggc gacccggatt
    69001 acccatccgg cattcggcca ttgcgccgcg cagcattttc agcgtgtggt cggcaatctc
    69061 atcttgcagg cacagcacgc gcagtgccga acaacgctga cctgcactgt cgaacgccga
    69121 ggccagcaca tctattacga cttgttcggt cagtgctgaa gaatcgacaa tcatcgcgtt
    69181 catgccgccg gtttcagcga tgagcggaat agggcgaccc tgagcgtcca ggcggctggc
    69241 gatattgcgc tgcagtaacg tagcgacttc ggttgaaccg gtaaacatca ccccgcgcac
    69301 gcgatcatca cccgtcagct gcgcgcccac ggtttcaccc cgaccgggca gcaattgcac
    69361 cacgcctggc ggtacacccg cttccagcaa aatggcgatc ccttgcgcgg caatcagcgg
    69421 cgtttgttct gccggttttg ccagcacgct gttacctgcc gccagtgcgg cagcgatctg
    69481 tccggtgaaa atcgccagcg ggaagttcca cggactgata cataccacag gccctaatgg
    69541 acggtgggtt tcgttagcga aatcatcccg cacctgtccg gcatagtagt ggagaaaatc
    69601 gaccgcttcg cgcacttcgg caatggcgtt actgaaggtt tttccggctt cacgcaccag
    69661 aataccaatc agttgctgca tctggctttc cattagcacg gcagcgcgat gcaaaattgc
    69721 cgcgcgttca gccggaggag tggcaaacca gattggcgcg ttattaaccg cactttccag
    69781 cgcctgttct acttcacgcg gcgtggcttc acgcacatag cccacaatat ctttcggttc
    69841 cgcagggtta ataacgggcg acatctcacc tgccgctacc ggttgttcca gcattggcaa
    69901 ggactgccat ttttgcagtg cactattgag cagggctgaa gagagcgagg ccagacggtg
    69961 ttcgttagcg agatccagcc ctgccgagtt gtcgcgcccg tgaccgtaaa gatcgcgcgg
    70021 caggggaatt ttcggatgcg gtaatccagt ttgcccttcc tgttgcgcca gtttttctac
    70081 agcagtgact ggatcggcga ccagttcatc cagtggcaaa gaggtgtcgg caatacggtt
    70141 aacaaacgag gtgttagcac cgttttccag caggcggcgc accagatacg ccagcagcgt
    70201 ttcatgtgta ccgaccggag cataaatacg acacggacgg ttaagtttgc cgtcggcaac
    70261 tttcccggtg acctgctcat acagtggttc gcccatacca tgcaggcact ggaactcgta
    70321 ctgacccggg tagtagtttt gacccgccag ttgataaatt gccgccagcg tatgggcgtt
    70381 gtgcgtcgcg aactgcgggt agattaaatt cggcaccgcc agcagttttt tcgcacaggc
    70441 aagataagaa acgtcggtat acaccttgcg ggtataaacc ggataacctt caaggccgtc
    70501 catctgtgca cgcttgattt cactatccca gtacgcgcct ttcaccaggc gaatcatcag
    70561 acggcgacgg ctgcgggtgg cgagatcaat caggtaatcg atcaccaacg ggcagcgttt
    70621 ttgataagcc tgaataacaa aaccgatgcc gttccagcct gccagttccg gctcgaaaca
    70681 gagtttttcc agcagatcga gggagatctc cagacgatcg gcctcttcgg catcgatgtt
    70741 aataccaata tcgtactgac gcgccagcag ggtgagtgat ttcagacgtg ggtaaagctc
    70801 ttccattacc cggtcatact gggcgcggct gtaacgcgga tgcagcgccg acagcttgat
    70861 tgaaatgccc ggaccttcat agatgccacg accattggac gctttaccaa tggcgtgaat
    70921 cgcctgctga taggaaacca tatacgcttg tgcatctgcg gcagtcagtg cggcttcgcc
    70981 cagcatatcg taagagtaac ggaaaccttt ctcttccagt ttgcgggcat tggctaacgc
    71041 ttccgcgatg gtttcgcccg tgacgaactg ctcgcccatc aggcgcatcg ccatatccac
    71101 acctttgcgg atcagcggtt caccgctctt accgataatg cggttcagcg agcgggagag
    71161 gctggcttcg ttatgggtgg aaaccagttt gccggtaaac agcagccccc aggtggcggc
    71221 attaacaaac aaagacgggc tacgaccaat gtgtgactgc cagttaccgt tgctgatttt
    71281 gtcgcgaatt aacgcgtccc gggtggcttt gtcgggaata cgcaacaacg cttctgccag
    71341 acacatcagc gccacgcctt cctgcgatga cagcgaaaac tcctgcaata acccctggac
    71401 catacctgcg cgaccactgg catttttttg attacgcagt ttatcggcca gttgatacgc
    71461 cagtttatgc gcctgttcag caactggttg cggcaggcgg gcttgttcca gcagcatcga
    71521 aaccgcttcg gtttccgggc ggcgataggc cgcggtgatc gcggcgcggg aaaccgactg
    71581 gggcaaaatt tgctcggcaa agtcgaggaa aggctggtgt ggttcctctg ccggagtcgg
    71641 tgcttcatcg ctctcattgg ccgcgccaga aagcagcgca ggtagctccg gaagagtatc
    71701 gctgttttcc agttgttcaa gataagaaaa aatcgcctgc ttaattaacc agtgtggcgt
    71761 gcgatcgata cgtgtcgcgg cagacttaat acgctcacgc gtcgcgtcgt ccagcttaac
    71821 ccccatggtg gtggttccca tgccattact cctgttgttc tgaaaggtgc aacttaacgt
    71881 tatcgtgaaa tatccatgat gttgcaactt tgtgcaacca tgttaaatgt gacctgcgta
    71941 gcaagcttaa aaatgaatga aatgttaata aaagaaatcg atatgacagg gattaaaaaa
    72001 ataactcaga ctttttctct gcggcagtta acatttttga aaggtgcaac cgcaaaaaat
    72061 gtgagagagt gcaacctgat gaaaaatagt gtcgctgagc actaaaattt aatgtaaatg
    72121 gtgtgttaaa tcgattgtga ataaccagcg cttccggcag gatacggtcg ccctggtaaa
    72181 acataaactc tgttaccccg ttccggtggc agatataacg gcaagtttcg acattgccga
    72241 taataatttt ttggagactt tagatggcta ttagcacacc gatgttggtg acattttgtg
    72301 tctatatctt tggcatgata ttgattgggt ttatcgcctg gcgatcaacg aaaaacttcg
    72361 acgactatat tctgggcggt cgtagtcttg ggccattcgt gacggcatta tcggcggggg
    72421 cgtcggatat gagcggctgg ctgttaatgg ggttgccagg cgctgttttt ctttccggga
    72481 tttccgaaag ctggatcgcc attggcctga cattaggcgc gtggatcaac tggaagctgg
    72541 tggccgggcg gttgcgtgtg cataccgaat acaacaataa cgccttaaca ttgccggatt
    72601 atttcaccgg gcgctttgaa gataaaagcc gcattttgcg cattatctcc gcgctggtta
    72661 ttttgctgtt cttcaccatt tattgcgctt cgggcattgt ggcaggcgcg cgtctgtttg
    72721 aaagtacctt tggcatgagc tacgaaacgg ctctgtgggc gggggctgcg gcgacgatcc
    72781 tttacacctt tattggcggt ttcctcgcgg tgagctggac tgacactgta caggccagcc
    72841 tgatgatttt tgccctgata ctgacgccgg ttatcgtaat cattagcgtt ggtgggtttg
    72901 gcgactcgct ggaagtgatc aaacaaaaga gcatcgaaaa cgtggatatg ctcaaagggc
    72961 tgaactttgt tgccattatc tcgctgatgg gctgggggct gggttacttc gggcaaccgc
    73021 acatcctggc gcgttttatg gcggcggatt ctcaccacag cattgtccat gcgcgtcgta
    73081 tcagtatgac ctggatgatc ctctgcctgg caggggcggt ggctgttggc ttctttggta
    73141 ttgcttactt taatgagcac ccggcggtag caggtgcggt aaatcagaac gctgaacgcg
    73201 tgtttatcga actggcgcaa attctgttta acccgtggat tgccgggatt ctgctgtcgg
    73261 cgattctggc ggcggtaatg tcaaccttaa gctgccagct gctggtatgt tccagtgcga
    73321 ttaccgaaga tttatacaaa gcgtttctgc gtaaacatgc cagccagaaa gagctggtgt
    73381 gggtagggcg tgtgatggtg ctggtggtgg cgctggtggc gattgcgctg gcggcaaacc
    73441 cggaaaaccg cgtgctgggc ttagtgagct acgcgtgggc aggctttggc gcggcgtttg
    73501 gtccggtggt gctgttctcg gtgatgtggt cacgcatgac gcgcaacggt gcgctggcgg
    73561 ggatgatcat cggtgcgctg acggttatcg tctggaaaca gttcggctgg ctgggtctgt
    73621 acgaaattat tccgggcttt atctttggta gtatcgggat tgtagtgttt agtttgctgg
    73681 gtaaagcgcc gtcagcggcg atgcaaaaac gctttgccga ggccgatgcg cactatcatt
    73741 cggctccgcc gtcacggttg caggaagggt aagagaaggc gttttaccga aaatttcacg
    73801 tcataacagg aagcaggcag agggcaatca gtgattgccc tctgcgtttt ttctcaaaat
    73861 atttttacat cttctcatca ttatcactac atttcacttg tatttttctt catcgtaatg
    73921 ataatcgcta tcactgcgat ttacttttct ttgcatagat tgactcagaa aaacgtttaa
    73981 gggtgggtgg catgtttgtt ccatttctca ttatgttgcg cgaaggactt gaagccgcgc
    74041 tgattgtcag tttgattgcc agctatctta agcgtaccca gcgaggccga tggattggtg
    74101 tgatgtggat tggcgtgttg cttgccgctg cgttgtgcct gggcttgggt atcttcatta
    74161 acgaaaccac cggtgaattt ccgcaaaaag aacaggaact gtttgaaggc atcgtggcgg
    74221 tgatcgccgt ggtgatcctt acctggatgg ttttctggat gcgcaaagtg tcgcgcaacg
    74281 tcaaagtaca actggagcag gcggtcgata gcgcattgca gcgtggaaat catcatggct
    74341 gggcgctggt gatgatggtt ttttttgccg ttgcaaggga agggctggag tcggtctttt
    74401 tcctgctggc ggcatttcaa caagatgtcg ggatctggcc gccgctgggt gcaatgctcg
    74461 gtcttgctac agccgtggtg cttggcttcc tgctctactg gggcggtatt cgcctcaatc
    74521 ttggtgcatt ttttaaatgg accagcctgt ttattctctt cgtcgccgca gggctggcgg
    74581 ctggtgccat tcgcgcattt catgaagccg gattgtggaa ccactttcag gaaatcgcct
    74641 tcgatatgag cgcggtgctc tcaactcact cgctgtttgg cacgctgatg gaagggattt
    74701 ttggctatca ggaagcgccg agtgtcagcg aagtcgccgt ctggtttatt tatctcatcc
    74761 cggcgctggt ggcatttgct ctgccaccac gcgcaggggc gacagcgtct cgctccgcgt
    74821 aacaaatacg acgcaaactc ttgcttagtt acaacatact ttaaagggat agtctcgtca
    74881 tgaccattaa cttccgccgt aacgcattgc agttgagcgt ggctgcgctg ttctcttctg
    74941 cttttatggc taacgccgct gatattccgc aagtcaaagt gaccgtaacg gataagcagt
    75001 gcgagccgat gaccattacg gttaatgccg gtaaaacaca gttcattatt cagaaccaca
    75061 gccagaaggc gctggagtgg gagatcctca aaggcgtgat ggtggtggaa gagcgggaaa
    75121 atatcgcccc tggctttagc cagaaaatga cggcgaattt acagcctggc gaatacgata
    75181 tgacctgcgg tctgctgact aacccgaaag ggaagttgat cgtcaaaggt gaggcaacgg
    75241 cggatgcggc gcaaagtgat gcgctgttaa gtcttggtgg tgcaattact gcatataaag
    75301 cgtatgtcat ggcggaaacc acgcagctgg tgaccgacac caaagccttt accgacgcga
    75361 ttaaagcagg cgatatcgaa aaagcgaaag cactgtatgc gccgacgcgc cagcactatg
    75421 agcgcattga accgattgct gaactgttct ccgatctgga tggcagcatt gacgcccgtg
    75481 aagatgatta cgagcaaaaa gccgccgatc caaaattcac cggtttccac cgtctggaaa
    75541 aagcattgtt tggcgataac accactaaag ggatggataa gtatgccgac cagctttata
    75601 ccgatgtggt cgatttgcaa aaacgcatca gtgaactggc tttcccacct tcaaaagtgg
    75661 tcggcggtgc agccggactg attgaggaag tggcagccag caaaatcagc ggtgaagaag
    75721 atcgctacag ccacaccgat ctgtgggatt tccaggctaa cgttgaaggc tcgcagaaaa
    75781 ttgtcgatct gctgcgtcca caactgcaaa aggccaaccc ggaactgctg gcaaaagtcg
    75841 atgccaattt caaaaaggtc gataccattc tggcgaaata ccgaaccaaa gacggttatg
    75901 aaacttacga caagctgacc gatgccgacc gtaatgcgct gaaagggccg attactgcgc
    75961 tggcggaaga tctggcgcaa tttcgtggtg tgctgggact ggattaagcg ttatgcagta
    76021 tgaagatgaa aacggcgtga atgaaccgtc acgccgacgt ttactgaaag ggattggcgc
    76081 gctggcgctg gcaggaagtt gtccggtagc gcatgctcaa aaaacgcaaa gtgcgccggg
    76141 gacgctttca ccggatgcgc gcagtgaagc gcagccgttt tatggcgaac atcaggcggg
    76201 tattctgacg ccgcagcagg cggcaatgat gctggtggcg tttgatgtgc ttgccagcga
    76261 taaaaccgat cttgaacggt tgtttcgctt gttgactcag cgttttgctt ttctgactca
    76321 gggcggagcg gcaccagaaa cgccaaatcc gcgcctgcca ccactcgatt ccggcattct
    76381 tggcggctac attgcgcccg ataatctcac cataacgtta tcggtgggtc actcattgtt
    76441 tgatgagcgc tttggccttg cgccacagat gccaaaaaag ttgcagaaga tgacgcgttt
    76501 ccctaacgac tcgctggatg cggcgttatg tcatggtgat gtgttgctac aaatttgcgc
    76561 caacacccag gacacggtga tccatgcgct gcgcgatatc atcaaacaca cgccggattt
    76621 gctcagcgtg cgctggaagc gggaagggtt tatttccgac cacgcagcgc gtagtaaagg
    76681 caaagagacg ccgataaatt tgctgggctt taaagacggc accgccaatc ccgatagcca
    76741 gaatgcgaag ttgatgcaaa aagtggtgtg ggtgacggca gatcagcagg agcctgcgtg
    76801 gacaatcggt ggcagctatc aggcagtacg cttgattcag tttcgggtgg aattttggga
    76861 cagaacgccg ctgaaagagc agcagacgat atttggtcgt gataagcaaa ccggtgcgcc
    76921 gctgggaatg cagcatgagc atgatgttcc cgattacgcc agcgatccgg aagggaaggt
    76981 gatcgcgctg gacagccata ttcggctggc gaatccccgc acgccagaga gtgagtcaag
    77041 tctgatgctg cgtcgtggct acagttattc actgggcgtc accaactccg ggcaactgga
    77101 tatggggcta ctgtttgtct gctaccaaca cgatctggaa aaaggcttcc tgacagtaca
    77161 aaaaaggctc aatggcgaag cgctggagga atacgttaaa cccatcggcg gcggttattt
    77221 ttttgcgctg ccgggagtga aggacgcgaa tgattatctc ggaagcgcgt tattgcgggt
    77281 ttgaacgacg caaatatgcc cgatgcgcag gtttatcggg catgagtttt gtgcacaaat
    77341 tattaatcac ttgtaggtcg ggtaaggcgt tcgcgcagca tccggcaaac acgaggcaca
    77401 ttttaccagc ccagcgaatc ctgctgaaag cacacagctt ttttcatcac tgtcatcact
    77461 ctgtcatctt tccagtagaa actaatgtca ctgaaatggt gttttatagt taaatataag
    77521 tgaatatatt gttgcaatga atgcgagatc tgttgtactt attaagtagc agcggaagtt
    77581 cccggcagtg atagtcagtc actatggaga tcgcggatgg taacgtcctg ttctggacaa
    77641 tgttttgtta agcaaggctc caccactcgc ggagatttct cctccggtag caacttcgtc
    77701 actctgtatt tttctcactt cctctcttta ctcgtgttac cgacgccgca aacggtgtgc
    77761 gtagccgttt ttcggcattt tatccaaaag caaactatgg cttacaagga agccaaccct
    77821 ctgatgttcg tgcgcataat cgcgctgcca acggcgcgtg tgatgaatac aaacaactca
    77881 aggtgctctc catgggaaga caaaaagcag tgatcaaagc tcgtcgcgag gcaaaacgtg
    77941 tgctgagacg ggattcgcgc agccataagc agcgtgaaga agaatcggtc acctcgcttg
    78001 tgcagatgag cggcgtagaa gccattggta tggcccgcga cagtcgcgat acttcgccca
    78061 tcctcgcgcg aaatgaagcg caattgcact atctgaaggc tattgagagt aagcagctga
    78121 tattcgccac gggcgaagct gggtgcggaa aaacctggat cagcgcagca aaagcggcag
    78181 aggccctgat acataaggat gtcgacagga ttatcgtcac ccgtccagtt ctgcaagccg
    78241 atgaagatct tggcttctta cctggtgata tcgcagaaaa gtttgctccc tattttcgcc
    78301 cggtctacga tgtgctggtc cggcgcttag gggcttcctt tatgcagtac tgcctgcgac
    78361 cagaaatagg gaaggtggaa attgcgccgt tcgcctatat gcgtggacgt acctttgaaa
    78421 atgcagtcgt cattcttgac gaggcgcaga atgtgactgc cgcgcaaatg aaaatgtttt
    78481 taacccgcct cggggagaac gtgacggtta tcgtcaacgg tgatatcacg caatgcgatt
    78541 tgcctcgcgg cgtgtgctcc ggattaagtg acgcgctgga acgtttcgaa gaggatgaaa
    78601 tggtcgggat cgtccgattc ggtaaagagg attgcgtacg ttcggcactt tgccaacgta
    78661 cgctacatgc atacagttaa gtgtattatc ggcgcagagc ccgggcgaac cgggctttgt
    78721 tttgggtgtt tatacccgga ctagcgtttt ttctgaaacc accattttta tttgtccctg
    78781 gctggtgaag tgtacgctca tcctgtggct tttttgtagt tgctgataaa gctcatcagg
    78841 tattgctaag ctctctgcat attctcgcgg cgtatattgg tatgctgcat gatgctgctg
    78901 ttttttaaaa cgcagcttat tgtacaatgc ccagacgatt aacacgacgg cattcgccac
    78961 tgccagcaaa aaatagaact gaagtcggct tctggcctcg ctttgccagt aataacccgt
    79021 cagcagatca atggcgaata agaatatgaa caaagcaaat aatgtccaca agatggttgt
    79081 ggcaacataa tcaaccagta aacgtactgg cgattgtcgg gtcgtaataa ttagattgtt
    79141 catattaacc tctcagaatc ccacgatcgg gacttaccca acgagcgcgt tgttttttag
    79201 gcatcaacat gactcgtgta aatgatacca atgtcgttgc caggcttagc atccagaaaa
    79261 taaccgggaa ccaaataatc cagaaaagcg atgaagccag attgtgctca tagcgattct
    79321 caatcaccag actgacaata aattgcagta aacataacgt acacaataat attccggcag
    79381 tatgtgtcgc tgcgatatgt gtcaattcaa tatttaacgg tacacctgca agttggactg
    79441 cgtaaataat gaaaccgacc aggcaggtaa aggcccatat tgtcgtcaga cagtattcaa
    79501 aaaacagtgg ccacattcga aagttttctt tgcgccatag ccttgtcata tttttgagga
    79561 atacttctgc accgccctga gcccagcgca ggcgctgttt ccacagccct tttaacgttt
    79621 caggcattaa tatccagcac agcgcccgtg gctcgtaaaa aatcgtccac tgattcaact
    79681 gcagcttcca gctaatatca atatcttcgg tgatcatatc gtcactccag taacccactt
    79741 ctgccagggc gctgcgacga aatgcggcaa taacaccgga aactgtaaat acgtttccat
    79801 agatacgctg ggtccgcttg atcaaaccaa taattgagga atactcgcca acctgaattt
    79861 tacccaccag ggtagaacgt gtgcgaatac gaggattacc ggttacggca cccacacgcg
    79921 ggttgtacaa catcggttcc acaatatatg ccgccgcatc gcggtctaat aacgcatcgc
    79981 catcaatgca caccagatat tcacttttcg ccgcggcagc tccggtttta agcgcaatgg
    80041 ctttcccctg gttttgcgcc agatgaatga cccgcaggtg gggaatttgt gcagccatgc
    80101 gatccaggat ggcacgggtt ttgtctgttg aaccgtcatt tacggcaata acttcaatgt
    80161 tctcataacg ctgtgctaaa gcggcgtgta tggtttcctc aacgtttttc tcctcattaa
    80221 aacagggaat gataatggag atagacggat tatctttcaa ctggggggct ggtgcgtttt
    80281 ctccccacgg ccagtggcgt tcacgataga cccagaaata gacgccgcca acaatccaca
    80341 taatggacat aaaaaacggc cagaagaaaa cgaacctcat catcagttca ccagagtgaa
    80401 agtacgctac gcataggggg atgcataaca ccagacataa tataaaaaac gatacgatgc
    80461 gattaatcat ttttcggata ccaggctgtt gaaaactcag gacgaataac gtctatttca
    80521 ggttggttat gcagaaaatt gtcgggataa taaccataat ttttcactcc attcagttgt
    80581 aataggctca tccagtgagc gagttgttgt gaagaaatag cctgatgctg accatttttc
    80641 tgccagtttt gtgcctgtaa ttctaaaatt gatttgtctt tagcctgcgg gatgcttttc
    80701 atctgattgg tcaattgtgt taaccattga tcagccaatt tttctgtgac gccttccata
    80761 taaggcatag ccataatagc ggtccagtca tagcttttta ggaaatcagc ataattctgt
    80821 gcaaaccagg cttcactttc aggttgtatt accggaagtg caaaaatatt tcgtgcagtt
    80881 ttaacatgtg gaccacgaat ggcttttacg cgcgcactaa gttctaaagt gaagtcagtt
    80941 aacgcacgac ttttaaagcg ggtccactgt ttaaattgct ccgggttttg tcgaatttcg
    81001 ctcagactcc cgctaaagcc agcttgctga taagccgcga tagccggtgc actggcatct
    81061 tcataatctg aaagcaaagc atcatcgtgg aacaatatgc catcaaaagc agcatgtccg
    81121 gcaagatcat catataacat gccaacttgt gctctgaccc tgtcatcgaa aggagagaga
    81181 cggcggtatt gttcaggatg aatttgtgct tttttctccc cagttggtaa gtattttact
    81241 cgcgttaatg tgggatctaa atcccagctt aataccggca tccacgcata gatgtttaca
    81301 cctgagcggg tacgcaattg ccaggcaacc cgactaaaaa tatctgcttt cattggtagc
    81361 aaacgatttg gaaaccagac ctctttaacc agcccatcac catcgggatc agcaaatgct
    81421 tgtaaataca cggtagatat ttgcatatct tttacccgct gaattagcac atcaatattg
    81481 cgatccattt gctggcggtt ttcgtcataa atgtaatcaa gatcgatatg cattacccgt
    81541 tgtagtggtt tttcctgtac ggtaataatt tgctgggcaa actcttttaa tgagggatta
    81601 ttggcgatta atactcgcgg aatggaatct aattgcgacg catttgccaa acctgattca
    81661 agggtgaaga acatgtcata accgagtttt tttaattccg cgattgctat gccattcgct
    81721 tcgccataag gccaaacaaa aacgtgtgga tttacctcag cctttgtacg caggtattcc
    81781 gtcattttta cagcatccag acgaattctt tcccggtatt ctgctgcggt ttcataccgt
    81841 gcgtggtcag taaaatatgc acgatttaca tatacaggca ataagctgcc ggtggcatta
    81901 gcctgaatac cgtagtgaga attccatgta tgagaagcga cctcaacgag ccgggaacgc
    81961 gcaacttctc gcacttgttg ccacgtggca aaatattctc gatcgaccat ctcatcgcca
    82021 aattttactt gttcatccgc tggcgtatcg acccaactgc cgacgggggc ccatacagca
    82081 ggccactgga aggcctgaag aattgggaag acgcgggtat aaaaactctg gtagccgtca
    82141 tcaaaagtca gcactactgc tttttccggt agcggttttc ctcctcgatg tgcttcacga
    82201 atttgagcaa tactgaccgg ttgataaccg ttctcgcgca gccaggcaaa ttgttcacgc
    82261 agtgctgatg ttcgcactga cataaaacgc tggtcggcag cttcgtcttc aacgttatgc
    82321 catgaaatcg ccacaaaacc attatgcggc cacggttgct cggcgagtaa agattcgcga
    82381 tcctgtggcg gtataaatga tgttcttgac tggctaatgc acgcagtgag cataattata
    82441 ctcaccagca tcaggatata tttatttcca ttacgtaaca tatttatcct taaaatctga
    82501 atgtcatatc gaattcaacg tataagttgt gttctctgtc accgtcataa ggtcgttttt
    82561 cccagcgtag cgttgcgcca gcatcaatca cgtcattcca gctaatacgt tgcccgtagc
    82621 cgagttgggt gacgacatcc gtgccataat gtttttgcca ggaggcacca acacctgcgc
    82681 tgaagatttg ctcccagcta ttttcatagc tacgccataa caaatgactt gcctcaaatg
    82741 ccggaacaat atcgaacgtt tttatagggt tgtagtatgg agtgtcgtgt tctgtatttt
    82801 gttcgtaata cagattgggt aggaaatcga caatcaaata tggtgaagac cagatgcgtt
    82861 cctgaccctc aagtgagact tcctgacgct ggttactgtc ggaaaaatca gtgaaagccc
    82921 aggagacacc gtacttacgc cgctcatttt gataccagcg aacataagcc tgagcactgt
    82981 tgcctgtaac accatttttc attgcccgta atggaacgcg gtgagagagg cgttccagtt
    83041 gcgaaccaat acgccagtta tcattaaaat cataccagcc agataggcgc gcgccgggtt
    83101 tatgctcatg attgaaaacg cgttcagcgt actccgcctc gagccagata ttacgtgacc
    83161 gccactcaac acccgccagc cagtcgcgaa caatcccttt tccttcgcta aattgtccat
    83221 cggcataacc gaatccagca aaaccgcgcc agttatcctt cagcggtggt gaataaacga
    83281 tggtggttaa gtcgacatca tgtttaccac tatccgggcc ttcggcatca attcctgttg
    83341 aaccagctat acgaagctct gcaagattat gtacatcaac cgcacgtttt aaacgtacaa
    83401 cgccgggatc ttgcggttca cgttcgacaa catcgtgcgt taagacagct gcctgctgcc
    83461 attcttgtaa cgttaatgct gtccatgctt gttcaacctc cagattaata ttacgtggct
    83521 cgatcacttc tgcttttttt aattcatttt ctgctgcacg aggccaaccg cgggcttgta
    83581 acacactcgc gtaatcaatg cgcagtccct gatttcctgg tgcgttataa gcaagctctc
    83641 tggctatcat ttcagcctga ggaagatcat tactatattt tgctacggtt gagagaaacg
    83701 aatgcccctg taaccaggta tcattcggga tgctcgtagg cgtgcccatt aaccgaagga
    83761 aaggcggcga agtattaatg gtatgttggg tgacagttag cgcgccggga taattttcac
    83821 tctccaggtg gctgtaaaag agatccgcaa gttcttcatc ggataaatcc ggggcaatgg
    83881 tctccttgtg ataaaagagc tctgtcatta ttgactgtgc tttttttggc tgatgttctt
    83941 tgagataagc cgacgcaacc caatattgcg cccagggtgg aataatttgc cccgtctttt
    84001 ttaaacgctg atagtgagaa ataacgtctt tataacgatc gcgagttaat aacgcgccaa
    84061 gatgatcaac ctgaatacgc tggtactggg cagtgcggtc agggttatca taccaaagaa
    84121 tttctaatgc agcgtattgg gcgagggcgc gatcggcaat ggcataacgt tcactttcac
    84181 tgcgcgtagg cataaacgac agtctgacca gttcggcatg aatatcagcg cgaatatctg
    84241 gcgttaaatt ggcatcgtca atcgcggcag taagttgatt attccgtaat gcctgcacgt
    84301 attctgtggg atattgttgc gttaaggcat tttcaggtaa tgatcctgtc atcgcccgta
    84361 attcatcctc atgccgcccc gccagtttat agatataggc ttctgcgagt aaattagctt
    84421 tgtccggtgc tccagagtta agctgcttaa gtttaaccag cgcagaatca tagtgacccg
    84481 catctgccag ggttaaaatt tgtccccgtt gataatcctt attttgcgac tccagagaga
    84541 gtgccttttg ccacagtgta agcgagtttt gccattgttg caggttacga taagcgacgg
    84601 cgacagctgc ataaccacgc gctggtaatt gctgatgacg gtagcggttg taaacggtaa
    84661 taacctgttt atcttgcccg gcccataagg caatctgtaa ccagtcagca atttggttat
    84721 tactgagagc tgatttttgt gcaaaccata acaaagctgg ctgagtattt cccttgcgag
    84781 cttcgataat caatgcatca taggcattat taacagcact cttcgccgcg ggactcgctg
    84841 ctaaaaatgc ggcagtaaga attttcaaag cccatttggt tttcgggcac ctttttctgc
    84901 tacttgaata catcctgtat tactccatgt attgccaaaa tctctctctg tatctaatta
    84961 caggtaactg aaacgaaaga tatttttttt gcacatcata atccgttatt aaacgcggaa
    85021 gagagacgtg aattgttgat gatgagaaga agaaatgatg agtagagtat ccatataaaa
    85081 tccttttctc gcccgaaaat ccatt
//
LOCUS       DADXDL010000010        79309 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.010, whole genome shotgun sequence.
ACCESSION   DADXDL010000010 DADXDL010000000
VERSION     DADXDL010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 79309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 79309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..79309
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.010"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(176..439)
                     /gene="cedA"
                     /locus_tag="IRB70_000901"
     CDS             complement(176..439)
                     /gene="cedA"
                     /locus_tag="IRB70_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division activator CedA"
                     /protein_id="HBC0630849.1"
                     /translation="MRLVKPVMKKPLRQQNRQIISYVPRTEPAPPEHAIKMDSFRDVW
                     MLRGKYVAFVLMGESFMRSPAFTVPESAQRWANQIRQEGEVTE"
     gene            622..2883
                     /gene="katE"
                     /locus_tag="IRB70_000902"
     CDS             622..2883
                     /gene="katE"
                     /locus_tag="IRB70_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase HPII"
                     /protein_id="HBC0630850.1"
                     /translation="MSQHNEKNPHQHQSPLHDSSEAKPGMDSLAPEDGSHRPAAEPTP
                     PGAQPTAPGSLKAPDTRNEKLNSLEDVRKGSENYALTTNQGVRIADDQNSLRAGNRGP
                     TLLEDFILREKITHFDHERIPERIVHARGSAAHGYFQPYKSLSDITKADFLSDPNKIT
                     PVFVRFSTVQGGAGSADTVRDIRGFATKFYTEEGIFDLVGNNTPIFFIQDAHKFPDFV
                     HAVKPEPHWAIPQGQSAHDTFWDYVSLQPETLHNLMWAMSDRGIPRSYRTMEGFGIHT
                     FRLINAEGKATFVRFHWKPLAGKASLVWDEAQKLTGRDPDFHRRELWEAIEAGDFPEY
                     ELGFQLIPEEDEFKFDFDLLDPTKLIPEELVPVQRVGKMVLNRNPDNFFAENEQAAFH
                     PGHIVPGLDFTNDPLLQGRLFSYTDTQISRLGGPNFHEIPINRPTCPYHNFQRDGMHR
                     MGLDTNPANYEPNSINDNWPRETPPGPKRGGFESYQERVEGNKVRERSPSFGEYYSHP
                     RLFWLSQTPFEQRHIVDGFSFELSKVVRPYIRERVVDQLAHIDLTLAQAVAKNLGIEL
                     TDDQLNITPPPDVNGLKKDPSLSLYAIPDGDVKGRVVAILLNDEVRSADLLAILKALK
                     AKGVHAKLLYSRMGEVTADDGTVLPIAATFAGAPSLTVDAVIVPCGNIADIADNGDAN
                     YYLMEAYKHLKPIALAGDARKFKATIKVADQGEEGIVEADSADGSFMDELLTLMAAHR
                     VWSRIPKIDKIPA"
     gene            complement(2930..3679)
                     /gene="chbG"
                     /locus_tag="IRB70_000903"
     CDS             complement(2930..3679)
                     /gene="chbG"
                     /locus_tag="IRB70_000903"
                     /EC_number="3.5.1.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitin disaccharide deacetylase"
                     /protein_id="HBC0630851.1"
                     /translation="MERLLIVNADDFGLSKGQNYGIIEACRNGIVTSTTALVNGQAID
                     HAVQLSRDEPSLTIGMHFVLTMGKPLTAMPGLTRDGVLGKWIWQLAEEDALPLEEITQ
                     ELASQYLRFIELFGRKPTHLDSHHHVHMFPQIFPIVARFAAEEGIALRADRQMVFDLP
                     VNLRTTQGFSSAFYGEEISESLFLQVLDDSSHRGERSLEVMCHPAFIDNTIRQSAYCF
                     PRLTELDVLTSASLKYAIAERGYRLGSYLDV"
     gene            complement(3692..5044)
                     /gene="celF"
                     /locus_tag="IRB70_000904"
                     /gene_synonym="chbF"
     CDS             complement(3692..5044)
                     /gene="celF"
                     /locus_tag="IRB70_000904"
                     /gene_synonym="chbF"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBC0630852.1"
                     /translation="MSQKLKVVTIGGGSSYTPELLEGFIKRYHELPVSELWLVDVEDG
                     KEKLDIIFDLCQRMIDNAGVPMKLYKTLDRREALKDADFVTTQLRVGQLPARELDERI
                     PLSHGYLGQETNGAGGLFKGLRTIPVIFDIVKDVEELCPNAWVINFTNPAGMVTEAVY
                     RHTGFKRFIGVCNIPIGMKMFIRDVLMLKDSDDLSIDLFGLNHMVFIKDVLVNGKSRF
                     AELLDGVASGQLKASGVKNIFELPFSEGLIRSLNLLPCSYLLYYFKQKEMLAIEMGEY
                     YKGGARAQVVQKVEKQLFELYKNPELKVKPKELEQRGGAYYSDAACEVINAIYNDKQA
                     EHYVNIPHHGHIDNIPADWAVEMTCTLGRDGATPHPRITHFDDKVMGLIHTIKGFEIA
                     ASNAALSGEFNDVLLALNLSPLVHSDRDAELLAREMILAHEKWLPNFADCIAELKKAH
                     "
     gene            complement(5149..5991)
                     /gene="chbR"
                     /locus_tag="IRB70_000905"
     CDS             complement(5149..5991)
                     /gene="chbR"
                     /locus_tag="IRB70_000905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ChbR"
                     /protein_id="HBC0630853.1"
                     /translation="MMQPMINAPEIATAREQQLFNGKNFHVFIYNKTESISGLHQHDY
                     YEFTLVLTGRYFQEINGKRVLLERGDFVFIPLGSHHQSFYEFGATRILNVGISKRFFE
                     QHYLPLLPYCFVASQVYRTNNAFLTYVETVISSLNFRETGLEEFVEMVTFYVINRLRH
                     YREEQVIDDVPQWLKSTVEKMHDKEQFSESALENMVTLSAKSQEYLTRATQRYYGKTP
                     MQIINEIRINFAKKQLEMTNYSVTDIAFEAGYSSPSLFIKTFKKLTSFTPKSYRKKLT
                     EFNQ"
     gene            complement(5999..6349)
                     /gene="chbA"
                     /locus_tag="IRB70_000906"
     CDS             complement(5999..6349)
                     /gene="chbA"
                     /locus_tag="IRB70_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIA"
                     /protein_id="HBC0630854.1"
                     /translation="MMDLDNIPDTQTEAEELEEVVMGLIINSGQARSLAYAALKQAKQ
                     GDFAAAKAMMDQSRMALNEAHLVQTKLIEGDAGEGKMKVSLVLVHAQDHLMTSMLARE
                     LITELIELHEKLKA"
     gene            complement(6400..7758)
                     /gene="chbC"
                     /locus_tag="IRB70_000907"
     CDS             complement(6400..7758)
                     /gene="chbC"
                     /locus_tag="IRB70_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIC"
                     /protein_id="HBC0630855.1"
                     /translation="MSNVIASLEKVLLPFAVKIGKQPHVNAIKNGFIRLMPLTLAGAM
                     FVLINNVFLSFGEGSFFYSLGIRLDASTIETLNGLKGIGGNVYNGTLGIMSLMAPFFI
                     GMALAEERKVDALAAGLLSVAAFMTVTPYSVGEAYAVGANWLGGANIISGIIIGLVVA
                     EMFTFIVRRNWVIKLPDSVPASVSRSFSALIPGFIILSVMGIIAWALNTWGTNFHQII
                     MDTISTPLASLGSVVGWAYVIFVPLLWFFGIHGALALTALDNGIMTPWALENIATYQQ
                     YGSVEAALAAGKTFHIWAKPMLDSFIFLGGSGATLGLILAIFIASRRADYRQVAKLAL
                     PSGIFQINEPILFGLPIIMNPVMFIPFVLVQPILAAITLAAYYMGIIPPVTNIAPWTM
                     PTGLGAFFNTNGSVAALLVALFNLGIATLIYLPFVVVANKAQNAIDKEESEEDIANAL
                     KF"
     gene            complement(7843..8163)
                     /gene="chbB"
                     /locus_tag="IRB70_000908"
     CDS             complement(7843..8163)
                     /gene="chbB"
                     /locus_tag="IRB70_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N,N'-diacetylchitobiose transporter subunit
                     IIB"
                     /protein_id="HBC0630856.1"
                     /translation="MEKKHIYLFCSAGMSTSLLVSKMRAQAEKYEVPVIIEAFPETLA
                     GEKGQNADVVLLGPQIAYMLPEIQRLLPNKPVEVIDSLLYGKVDGLGVLKAAVAAIKK
                     AAAN"
     gene            complement(8462..8800)
                     /gene="osmE"
                     /locus_tag="IRB70_000909"
     CDS             complement(8462..8800)
                     /gene="osmE"
                     /locus_tag="IRB70_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotically-inducible lipoprotein OsmE"
                     /protein_id="HBC0630857.1"
                     /translation="MNKNMAGILSAAAVLTMLAGCTAYDRTKDQFVQPVVKDVKKGMS
                     RAQVAQIAGKPSSEVSMIHARGTCQTYILGQRDGKAETYFVALDDTGHVINSGYQTCA
                     EYDTDPQAAK"
     gene            9002..9829
                     /gene="nadE"
                     /locus_tag="IRB70_000910"
     CDS             9002..9829
                     /gene="nadE"
                     /locus_tag="IRB70_000910"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBC0630858.1"
                     /translation="MTLQQQIIKALGAKPQINAEEEIRRSVDFLKSYLQTYPFIKSLV
                     LGISGGQDSTLAGKLCQMAINELRQETGNESLQFIAVRLPYGVQADEQDCQDAIAFIQ
                     PDRVLTVNIKGAVLASEQALREAGIELSDFVRGNEKARERMIVQYSIAGMTSGVVVGT
                     DHAAEAITGFFTKYGDGGTDINPLYRLNKRQGKQLLAALGCPEHLYKKAPTADLEDDR
                     PSLPDEVALGVTYDNIDDYLEGKNLPEQVARTIENWYLKTEHKRRPPITVFDDFWKK"
     gene            10059..10946
                     /gene="cho"
                     /locus_tag="IRB70_000911"
     CDS             10059..10946
                     /gene="cho"
                     /locus_tag="IRB70_000911"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease Cho"
                     /protein_id="HBC0630859.1"
                     /translation="MVRRLTSPRLEFEAAAIYEYPEHLRSFLNDLPTRPGVYLFHGES
                     DTMPLYIGKSINIRSRVLSHLRTPDEAAMLRQSRRISWICTAGEIGALLLEARLIKEQ
                     QPLFNKRLRRNRQLCALQLNEKRVDVVYAKEVDFSRAPNLFGLFANRRAALQALQTIA
                     DEQKLCYGLLGLEPLSRGRACFRSALKRCAGACCGKESHDDHALRLRQSLERLRVVCW
                     PWKGAVALKEQHPEMTQYHIIQNWLWLGAVNSLEEATMLIRTPAGFDHDGYKILCKPL
                     LSGNYEITELDPANDQRAS"
     gene            complement(10906..11481)
                     /gene="ves"
                     /locus_tag="IRB70_000912"
     CDS             complement(10906..11481)
                     /gene="ves"
                     /locus_tag="IRB70_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310475.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="environmental stress-induced protein Ves"
                     /protein_id="HBC0630860.1"
                     /translation="MEYFDMRKMSVNLWRNAAGETREICTFPPAKRDFYWRASIASIA
                     ANGEFSLFPGMERIVTLLEGGEMFLESTDRFNHTLKPLQPFAFAADQVVKAKLTAGQM
                     SMDFNIMTRLDVCKAKVRIAERTFTTFGSRGGVVFVINGAWQLGDKLLTTDQGACWFD
                     GRHTLRLLQPQGKLLFSEINWLAGHSPDQVQ"
     gene            complement(11684..12169)
                     /gene="spy"
                     /locus_tag="IRB70_000913"
     CDS             complement(11684..12169)
                     /gene="spy"
                     /locus_tag="IRB70_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-independent periplasmic protein-refolding
                     chaperone"
                     /protein_id="HBC0630861.1"
                     /translation="MRKLTALFVASTLALGAANLAHAADTTTSAPADAKPMMHHKGKF
                     GPHQDMMFKDLNLTDAQKQQIREIMKGQRDQMKRPPLEERRAMHDIIASDTFDKAKAE
                     AQIAKMEEQRKANMLAHMETQNKIYNILTPEQKKQFNANFEKRLTERPAAKGKMPATA
                     E"
     gene            complement(12499..13467)
                     /gene="astE"
                     /locus_tag="IRB70_000914"
     CDS             complement(12499..13467)
                     /gene="astE"
                     /locus_tag="IRB70_000914"
                     /EC_number="3.5.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate desuccinylase"
                     /protein_id="HBC0630862.1"
                     /translation="MDNFLALTLTGKKPVITEREINGVRWRWLGDGVLELTPLTPPQG
                     ALVISAGIHGNETAPVEMLDALLGAISHGEIPLRWRLLVILGNPPALKQGKRYCHSDM
                     NRMFGGRWQLFAESGETCRARELEQCLEDFYDQGKESVRWHLDLHTAIRGSLHPQFGV
                     LPQRDIPWDEKFLTWLGAAGLEALVFHQEPGGTFTHFSARHFGALACTLELGKALPFG
                     QNDLRQFAVTASAIAALLSGESVGIVRTPPLRYRVVSQITRHSPSFEMHMANDTLNFM
                     PFEKGTLLAQDGEERFTVTHDVEYVLFPNPLVALGLRAGLMLEKIS"
     gene            complement(13460..14803)
                     /gene="astB"
                     /locus_tag="IRB70_000915"
     CDS             complement(13460..14803)
                     /gene="astB"
                     /locus_tag="IRB70_000915"
                     /EC_number="3.5.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-succinylarginine dihydrolase"
                     /protein_id="HBC0630863.1"
                     /translation="MNAWEVNFDGLVGLTHHYAGLSFGNEASTRHRFQISNPRLAAKQ
                     GLLKMKTLADAGFPQAVIPPHERPFIPVLRQLGFSGSDEQVLEKVARQAPHWLSSVSS
                     ASPMWVANAATIAPSADTLDGKVHLTVANLNNKFHRSLEAPVSESLLKAIFNNEEKFS
                     VHSALPQVALLGDEGAANHNRLGGHYGEPGMQLFVYGREEGNDTRPSRYPARQTREAS
                     EAVARLNQVNPQQVIFAQQNPDVIDQGVFHNDVIAVSNRQVLFCHQQAFARQVQLLAN
                     LRARVNGFMAIEVPATQVSVSDAVSTYLFNSQLLSRDDGSMMLVLPQECREHAGVWGY
                     LNELLAADNPISELKVFDLRESMANGGGPACLRLRVVLTEEERRAVNPAVMMNDTLFN
                     ALNDWVDRYYRDRLTAADLADPQLLREGREALDVLSQLLNLGSVYPFQREGGGNG"
     gene            complement(14800..16278)
                     /gene="astD"
                     /locus_tag="IRB70_000916"
     CDS             complement(14800..16278)
                     /gene="astD"
                     /locus_tag="IRB70_000916"
                     /EC_number="1.2.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylglutamate-semialdehyde dehydrogenase"
                     /protein_id="HBC0630864.1"
                     /translation="MTLWINGDWITGQGASRVKRNPVSGEVLWQGNDADAAQVGQACR
                     AARAAFPRWARLSFGDRQVRVERFAGLLESNKAELTAIIARETGKPRWEAATEVTAMI
                     NKIAISIKAYHVRTGEQRSEMPDGAASLRHRPHGVLAVFGPYNFPGHLPNGHIVPALL
                     AGNTIIFKPSELTPWSGEAVMRLWQQAGLPPGVLNLVQGGRETGQALSALEDLDGLLF
                     TGSANTGYQLHRQLSGQPEKILALEMGGNNPLIIDEAADIDAAVHLTIQSAFVTAGQR
                     CTCARRLLLKSGAQGDAFLARLVAVSQRLTPGNWDDEPQPFIGGLISEQAAQQVVTAW
                     QELEAMGGRTLLAPRLLRAGTSLLTPGIIEMTGVTGVPDEEVFGPLLRVWRYDTFDEA
                     ITMANNTRFGLSCGLVSPAREKFDQLLLEARAGIVNWNKPLTGAASTAPFGGIGASGN
                     HRPSAWYAADYCAWPMASLESDSLTLPATLNPGLDFSDEVVR"
     gene            complement(16275..17309)
                     /gene="astA"
                     /locus_tag="IRB70_000917"
     CDS             complement(16275..17309)
                     /gene="astA"
                     /locus_tag="IRB70_000917"
                     /EC_number="2.3.1.109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine N-succinyltransferase"
                     /protein_id="HBC0630865.1"
                     /translation="MMVIRPVERSDVSALMQLASKTGGGLTSLPANEATLSARIERAI
                     KTWQGELPKSEQGYVFVLEDSETGTVAGICAIEVAVGLNDPWYNYRVGTLVHASKELN
                     VYNALPTLFLSNDHTGSSELCTLFLDPDWRKEGNGYLLSKSRFMFMAAFRDKFNDKVV
                     AEMRGVIDEHGYSPFWQSLGKRFFSMDFSRADFLCGTGQKAFIAELMPKHPIYTHFLS
                     QEAQDVIGQVHPQTAPARAVLEKEGFRYRNYIDIFDGGPTLECDIDRVRAIRKSRLVE
                     VAEGQPAQGDFPACLVANENYHHFRVVLVRTDPATERLILTAAQLDALKCHAGDRVRL
                     VRLCAEEKTA"
     gene            complement(17306..18526)
                     /gene="astC"
                     /locus_tag="IRB70_000918"
     CDS             complement(17306..18526)
                     /gene="astC"
                     /locus_tag="IRB70_000918"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.81"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinylornithine/acetylornithine transaminase"
                     /protein_id="HBC0630866.1"
                     /translation="MSQPITRENFDEWMIPVYAPAPFIPVRGEGSRLWDQQGKEYIDF
                     AGGIAVNALGHAHPELREALNEQASKFWHTGNGYTNEPVLRLAKKLIDATFADRVFFC
                     NSGAEANEAALKLARKFAHDRYGSHKSGIVAFKNAFHGRTLFTVSAGGQPAYSQDFAP
                     LPPDIHHAAYNDINSASALIDDATCAVIVEPIQGEGGVVPASNAFLQGLRELCDRHNA
                     LLIFDEVQTGVGRTGELYAYMHYGVTPDLLTTAKALGGGFPVGALLATEECASVMTVG
                     THGTTYGGNPLASAVAGKVLDLINTPEMLNGVKQRHDWFVERLNSINHHYGLFSEVRG
                     LGLLIGCVLNADYAGQAKQISQEAAKAGVMVLIAGGNVVRFAPALNVSEEEVTTGLDR
                     FAAACEHFVSRGSS"
     gene            18972..19778
                     /gene="xthA"
                     /locus_tag="IRB70_000919"
     CDS             18972..19778
                     /gene="xthA"
                     /locus_tag="IRB70_000919"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBC0630867.1"
                     /translation="MKFVSFNINGLRARPHQLEAIVEKHQPDVIGLQETKVHDDMFPL
                     EEVAKLGYNVFYHGQKGHYGVALLTKETPIAVRRGFPGDDEEAQRRIIMAEIPSPLGN
                     VTVINGYFPQGESRDHPIKFPAKAQFYQNLQNYLETELKRENPVLIMGDMNISPGDLD
                     IGIGEENRKRWLRTGKCSFLPEEREWMERLMSWGLVDTFRHANPQTADRFSWFDYRSK
                     GFDDNRGLRIDLLLASQPLAECCVETGIDYEIRSMEKPSDHAPVWATFRR"
     gene            19945..20655
                     /locus_tag="IRB70_000920"
     CDS             19945..20655
                     /locus_tag="IRB70_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310483.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBC0630868.1"
                     /translation="MNAERKFLFACLIFALVIYAIHAFGLFELLTDLPHLQTLIRQSG
                     LFGYSLYILLFIIATLFLLPGSILVIAGGIVFGPFLGTLLSLIAATLASSCSFLLARW
                     LGRDLLLKYVGHSHTFKAIEKGIARNGINFLILTRLIPLFPYNIQNYAYGLTTIAFWP
                     YTLISALTTLPGIVIYTVMASDLANEGITLRFILQLCLAGLALFILVQLAKLYARHKH
                     VDLSASRRSPLTHPKNEG"
     gene            20660..21337
                     /gene="ydjY"
                     /locus_tag="IRB70_000921"
     CDS             20660..21337
                     /gene="ydjY"
                     /locus_tag="IRB70_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310484.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YdjY"
                     /protein_id="HBC0630869.1"
                     /translation="MLQHYSVSWKKGLTALCLLAVAGLSGCDQKENAAAKVEYDGLSN
                     SQPLRVDANNHTVTMLVQINGRFLTDDTRHGIVFKDGSNGHKSLFMGYATPKAFYEAL
                     KEAGGTPGENMTMDNKETTHVTGSKLEISVNWQGAAKAYSFDEVIVDSNGKKLDMRFG
                     GNLTAAEEKKTGCLVCLDSCPVGIVSNATYTYGAVEKRGEVKFKGNASVLPADNTLAT
                     VTFKITE"
     gene            21352..22059
                     /locus_tag="IRB70_000922"
     CDS             21352..22059
                     /locus_tag="IRB70_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBC0630870.1"
                     /translation="MMKMQSRKIWYYRITLIILLFAMLLAWALLPGVHEFINRSVAAF
                     AAVDQQGIERFIQSYGALAAVVSFLLMILQAIAAPLPAFLITFANASLFGALWGGLLS
                     WTSSMAGAALCFFIARVMGREVVEKLTGKTVLNSMDGFFTRYGKHTILVCRLLPFVPF
                     DPISYAAGLTSIRFRSFFIATGLGQLPATIVYSWAGSMLTGGTFWFVTGLFILFALTV
                     VIFMAKKIWLERQKRNA"
     gene            22059..22607
                     /locus_tag="IRB70_000923"
     CDS             22059..22607
                     /locus_tag="IRB70_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBC0630871.1"
                     /translation="MGLPPLSKIPFILRPQAWLHRRHYGEVLSPIRWWGRIPFIFYLV
                     SMFVGWLERKRSPLDPVVRSLVSARIAQMCLCEFCVDITSMKVAERTGSTDKLLAVAD
                     WRQSPLFSDEERLALEYAEAASVTPPTVDDALRTRLATHFDAQALTELTALIGLQNLS
                     ARFNSAMDIPAQGLCRIPDKRS"
     gene            22617..23783
                     /locus_tag="IRB70_000924"
     CDS             22617..23783
                     /locus_tag="IRB70_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBC0630872.1"
                     /translation="MRHCVWLLGLLSLFSLATHASDWQEIKNEAKGQTVWFNAWGGDT
                     AINRYLDWVSGEMKTHYAINLKIVRLADAADAVKRIQTEAAAGRKTGGSVDLLWVNGE
                     NFRTLKEANLLQTGWAETLPNWRYVDTQLPVREDFSVPTEGAESPWGGAQLTFIARRD
                     VTPQPPQTPQALLEFAKANPGTVTYPRPPDFTGTAFLEQLLIMLTPDPAALKEAPDDA
                     TFARVTTPLWQYLDALHPYLWREGKDFPPSPARMDALLKANTLRLSLTFNPAHAQQKI
                     ASGDLPASSYSFGFREGMIGNVHFVTIPANANASAAAKVVANFLLSPDAQLRKADPAV
                     WGDPSVLDPQKLPDGQRESLQSRMPQDLPPVLAEPHAGWVNALEQEWLHRYGTH"
     gene            23756..25291
                     /locus_tag="IRB70_000925"
     CDS             23756..25291
                     /locus_tag="IRB70_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310488.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0630873.1"
                     /translation="MATPLRYALIFLLWAMVAVIYAPLIPATLTLISPALSLTHWQAL
                     FADPQLPQALLATLVSTTIAAVGALLIALLVIVALWPGPKWQRMCARLPWLLAIPHVA
                     FASSALLLFADGGLLYDYFPYFTPPMDKLGIGLGLTLAVKESAFLLWILAAVLSEKRL
                     LQQVIVLDSLGYSRWQCLKWLLLPSVAPALAMAMLAIVAWSLSVVDVAITLGPGNPPT
                     LAVISWQWLTQGDADQQTKGALASLLLMLLLAAYVLLGYLLWRSWRRTIPRVDGVRKP
                     ATPLLPGITLASFLPLTGVLCVVLLAILADQSTINSEALINSLTMGLVATFIALLLLL
                     LWLEWGPQRRQLWLWLPILLPALPLVAGQYTLALWLNLDGSWTAVVWGHLLWVMPWML
                     FILQPAWQRIDSRLILIAQTLGWSRAKIFFYVKCPLMLRPALIAFAVGFSVSIAQYMP
                     TLWLGAGRFPTLTTEAVALSSGGSNGILAAQALWQLLLPLIIFALTALVAKWVGYVRQ
                     GLR"
     gene            25291..25944
                     /locus_tag="IRB70_000926"
     CDS             25291..25944
                     /locus_tag="IRB70_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBC0630874.1"
                     /translation="MLCVKNVSLRLPESRLLTNVNFTVDKGDIVTLMGPSGCGKSTLF
                     SWMIGALAGQFSCTGELWLNEQRIDMLPTAERQIGILFQDALLFDQFSVGQNLLLALP
                     AALKGVARRDAVNDALERAGLGGMFHQDPATLSGGQRARVALLRALLAQPKALLLDEP
                     FSRLDVALRDNFRQWVFSEVHALAIPVVQVTHDLQDVPADSSVLDMAQWSENYNKLR"
     gene            26011..27318
                     /gene="ynjE"
                     /locus_tag="IRB70_000927"
     CDS             26011..27318
                     /gene="ynjE"
                     /locus_tag="IRB70_000927"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YnjE"
                     /protein_id="HBC0630875.1"
                     /translation="MKRVSQMTALAMALGLACASSWAAELAKPLTLDQLQQQNGKAID
                     TRPSAFYNGWPQTLNGPSGHEPAALNLSASWLDKMSTEQLNAWIKQHNLKADAPVALY
                     GNDKDVDAVKTRLQKAGFTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKEV
                     TAKPAGDWKVIEAAWGAPKLYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKH
                     GIRHDTTVILYGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKV
                     KTEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGE
                     IAGARWGHAGSDSTHMEDFHNPDGTMRSADDITAMWKAWNIRPDQQVSFYCGTGWRTS
                     ETFMYARAMGWNNVSVYDGGWYEWSSDPKNPVATGERGPDSSK"
     gene            complement(27327..27947)
                     /locus_tag="IRB70_000928"
     CDS             complement(27327..27947)
                     /locus_tag="IRB70_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707357.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBC0630876.1"
                     /translation="MLDRHLHPRIKPLLHQCVRVLDKPGITPDGLTLVGFAIGVLALP
                     FLALGWYLAALVAILLNRLLDGLDGALARRRGLTDAGGFLDISLDFLFYALVPFGFIL
                     AAPEQNALAGGWLLFAFIGTGSSFLAFAALAAKHQIDNPGYAHKSFYYLGGLTEGSET
                     ILLFVLSCLFPACFPWFAWVFGALCWMTTFTRVWSGYLTLKSLQRQ"
     gene            28034..28441
                     /gene="nudG"
                     /locus_tag="IRB70_000929"
     CDS             28034..28441
                     /gene="nudG"
                     /locus_tag="IRB70_000929"
                     /EC_number="3.6.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP pyrophosphohydrolase"
                     /protein_id="HBC0630877.1"
                     /translation="MKMIEVVAAIIERDGKILLAQRPAHSDQAGLWEFAGGKVEPDES
                     QRQALVRELREELGIEAAVSEYVASHQREVSGRIIHLHAWHVPDFHGTLQAHEHQALV
                     WCSPEEALQYPLAPADIPLLEAFMALRAARPAD"
     gene            complement(28407..28679)
                     /locus_tag="IRB70_000930"
     CDS             complement(28407..28679)
                     /locus_tag="IRB70_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnjH family protein"
                     /protein_id="HBC0630878.1"
                     /translation="MSRALFAVVLAFPLIALANPHYHPDVEVNVPPEVFSSGGQSAQP
                     CTQCCVYQDQNYSEGAVIKAEGILLQCQRDDKTLSTNPLVWRRVKP"
     gene            28915..30258
                     /gene="gdhA"
                     /locus_tag="IRB70_000931"
     CDS             28915..30258
                     /gene="gdhA"
                     /locus_tag="IRB70_000931"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBC0630879.1"
                     /translation="MDQTYSLESFLNHVQKRDPNQTEFAQAVREVMTTLWPFLEQNPK
                     YRQMSLLERLVEPERVIQFRVVWVDDRNQVQVNRAWRVQFSSAIGPYKGGMRFHPSVN
                     LSILKFLGFEQTFKNALTTLPMGGGKGGSDFDPKGKSEGEVMRFCQALMTELYRHLGA
                     DTDVPAGDIGVGGREVGFMAGMMKKLSNNTACVFTGKGLSFGGSLIRPEATGYGLVYF
                     TEAMLKRHGMGFEGMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVDESGFTK
                     EKLARLIEIKASRDGRVADYAKEFGLVYLEGQQPWSVPVDIALPCATQNELDVDAAHQ
                     LIANGVKAVAEGANMPTTIEATELFQQAGVLFAPGKAANAGGVATSGLEMAQNAARLG
                     WKAEKVDARLHHIMLDIHHACVEHGGEGDQTNYVQGANIAGFVKVADAMLSQGVI"
     gene            complement(30335..32290)
                     /gene="topB"
                     /locus_tag="IRB70_000932"
     CDS             complement(30335..32290)
                     /gene="topB"
                     /locus_tag="IRB70_000932"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBC0630880.1"
                     /translation="MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGH
                     LLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPSVTKQLNVIKRFLHEASEIVHAG
                     DPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
                     SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVA
                     KDFFEVKAHIVTPADERFTAIWQPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIV
                     TSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLYETHKLITYPRSDCR
                     YLPEEHFAGRHAVMNAISVHAPDLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSA
                     INLTENEAKVYNLIARQYLMQFCPDAVFRKCVIELDIAKGKFVAKARFLAEAGWRTLL
                     GSKERDEENDGMPLPVVAKGDELLCEKGEVVERQTQPPRHFTDATLLSAMTGIARFVQ
                     DKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHSLPEMAT
                     RPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQAKRTSVRQFRGIMAPGGGE
                     GKKKDSPRKRAPKKSPPSEEAGNGVII"
     gene            complement(32295..33338)
                     /gene="selD"
                     /locus_tag="IRB70_000933"
     CDS             complement(32295..33338)
                     /gene="selD"
                     /locus_tag="IRB70_000933"
                     /EC_number="2.7.9.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenide, water dikinase SelD"
                     /protein_id="HBC0630881.1"
                     /translation="MSENSIRLTQYSHGAGCGCKISPKVLETILHSEQAKFVDPNLLV
                     GNETRDDAAVYDLGNGTSVISTTDFFMPIVDNPFDFGRIAATNAISDIFAMGGKPIMA
                     IAILGWPINKLSPEIAREVTEGGRYACRQAGIALAGGHSIDAPEPIFGLAVTGIVPTE
                     RVKKNSTAQAGCKLFLTKPLGIGVLTTAEKKSLLKPEHQGLATEVMCRMNIAGASFAN
                     IEGVKAMTDVTGFGLLGHLSEMCQGAGVQARVDYDAIPKLPGVEEYIKLGAVPGGTER
                     NFASYGHLMGEMPREVRDLLCDPQTSGGLLLAVMPEAENEVKATAAEFGIELTAIGEL
                     VPARGGRAMVEIR"
     gene            complement(33455..34006)
                     /locus_tag="IRB70_000934"
     CDS             complement(33455..34006)
                     /locus_tag="IRB70_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H nitroreductase"
                     /protein_id="HBC0630882.1"
                     /translation="MDALELLINRRSASRLAEPAPTGEQLQNILRAGMRAPDHKSMQP
                     WHFFVIEGEGRERFSAVLEQGAIAAGSDNKAIDKARNAPFRAPLIITVVAKCEENHKV
                     PRWEQEMSAGCAVMAMQMAAVAQGFGGIWRSGALTESPVVREAFGCREQDKIVGFLYL
                     GTPQLKASTSINVPDPTPFVTYF"
     gene            34167..36023
                     /gene="sppA"
                     /locus_tag="IRB70_000935"
     CDS             34167..36023
                     /gene="sppA"
                     /locus_tag="IRB70_000935"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707347.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBC0630883.1"
                     /translation="MRTLWRFIAGFFKWTWRLLNFVREMVLNLFFIFLVLVGVGIWMQ
                     VSGGDSKETASRGALLLDISGVIVDKPDSSQRFSKLSRQLLGASSDRLQENSLFDIVN
                     TIRQAKDDRNITGIVMDLKNFAGGDQPSMQYIGKALKEFRDSGKPVYAVGENYSQGQY
                     YLASFANKIWLSPQGVVDLHGFATNGLYYKSLLDKLKVSTHVFRVGTYKSAVEPFIRD
                     DMSPAAREADSRWIGELWQNYLNTVAANRQIPAQQVFPGAQGLLEGLTKTGGDTAKYA
                     LENKLVDALASSAEIEKTLTKEFGWSKTDKNYRAISYYDYALKTPADTGDSIGVVFAN
                     GAIMDGEETQGNVGGDTTAAQIRDARLDPKVKAIVLRVNSPGGSVTASEVIRAELAAA
                     RAAGKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGV
                     HTDGVSTSPLADVSITRALPPEAQQMMQLSIENGYKRFITLVADARHSTPEQIDKIAQ
                     GHVWTGQDAKANGLVDSLGDFDDAVAKAAELAKVKQWHLEYYVDEPTFFDKVMDNMSG
                     SVRAMLPDAFQAMLPAPLASVASTVKSESDKLAAFNDPQNRYAFCLTCANVR"
     gene            36190..37206
                     /gene="ansA"
                     /locus_tag="IRB70_000936"
     CDS             36190..37206
                     /gene="ansA"
                     /locus_tag="IRB70_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBC0630884.1"
                     /translation="MQKKSIYVAYTGGTIGMQRSEQGYIPVSGHLQRQLALMPEFHRP
                     EMPDFTIHEYTPLMDSSDMTPEDWQHIAEDIKAHYDDYDGFVILHGTDTMAYTASALS
                     FMLENLGKPVIVTGSQIPLAELRSDGQINLLNALYVAANYPINEVTLFFNNRLYRGNR
                     TTKAHADGFDAFASPNLPPLLEAGIHIRRLNTPPAPHGEGELIVHPITPQPIGVVTIY
                     PGISADVVRNFLRQPVKALILRSYGVGNAPQNKAFLQELQEASDRGIVVVNLTQCMSG
                     KVNMGGYATGNALAHAGVIGGADMTVEATLTKLHYLLSQELDTETIRKAMSQNLRGEL
                     TPDD"
     gene            37217..37858
                     /gene="pncA"
                     /locus_tag="IRB70_000937"
     CDS             37217..37858
                     /gene="pncA"
                     /locus_tag="IRB70_000937"
                     /EC_number="3.5.1.-"
                     /EC_number="3.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001587135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional nicotinamidase/pyrazinamidase"
                     /protein_id="HBC0630885.1"
                     /translation="MPPRALLLVDLQNDFCAGGALAVPEGDSTVDVANRLIDWCQSRG
                     EAVIASQDWHPANHGSFASQHGVEPYTPGQLDGLPQTFWPDHCVQNSEGAQLHPLLNQ
                     KAIAAVFHKGENPLVDSYSAFFDNGRRQKTALDDWLRAHVINELIVMGLATDYCVKFT
                     VLDALQLGYKVNVITDGCRGVNIQPQDSAHAFMEMSAAGATLYTLADWEETQE"
     gene            complement(37951..39309)
                     /locus_tag="IRB70_000938"
     CDS             complement(37951..39309)
                     /locus_tag="IRB70_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630886.1"
                     /translation="MEQYDQIGARLDRLPLARFHYRIFGIISFSLLLTGFLSYSGNVV
                     LAKLVSNGWSNNFLNAAFTSALMFGYFIGSLTGGFIGDYFGRRRAFRINLLIVGIAAT
                     GAAFVPDMYWLIFFRFLMGTGMGALIMVGYASFTEFIPATVRGKWSARLSFVGNWSPM
                     LSAAIGVVVIAFFSWRIMFLLGGIGILLAWFLSGKYFIESPRWLAGKGQIAGAESQLR
                     EVEQQIEREKSVRLPPLTLNQSNSKVKVIKGTFWLLFKGEMLRRTLVAITVLIAMNIS
                     LYTITVWIPTIFVNSGIDVDKSILMTAVIMIGAPVGIFIAALIIDHFPRRLFGSALLI
                     IIAVLGYIYSIQTTEWAILIYGLVMIFFLYMYVCFASAVYIPELWPTHLRLRGSGFVN
                     AVGRIVAVFTPYGVAALLTHYGSITVFMVLGVMLVLCALVLSIFGIETRKVSLEEISE
                     VN"
     gene            complement(39426..40184)
                     /locus_tag="IRB70_000939"
     CDS             complement(39426..40184)
                     /locus_tag="IRB70_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBC0630887.1"
                     /translation="MAAKDRIQAIKQMVANDKKVTVSNLSGIFQVTEETIRRDLEKLE
                     DEGFLTRTYGGAVLNTAMLTENIHFYKRASSFYEEKQLIARKALPFIDNKTTMAADSS
                     STVMELLKLLQDRSDLTLLTNSAEAIHVLAQSEIKVVSTGGELNKNTLSLQGRITKEI
                     ISRYHVDIMVMSCKGLDINSGALDSNEAEAEIKKTMIRQATEVALLVDHSKFDRKAFV
                     QLADFSHINYIITDKSPGAEWIAFCKDNNIQLVW"
     gene            complement(40321..41301)
                     /gene="ydjG"
                     /locus_tag="IRB70_000940"
     CDS             complement(40321..41301)
                     /gene="ydjG"
                     /locus_tag="IRB70_000940"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent methylglyoxal reductase"
                     /protein_id="HBC0630888.1"
                     /translation="MKKIPLGTTDITLSRMGLGTWAIGGGPAWNGDLDRQICIDTILE
                     AHRCGINLIDTAPGYNFGNSEVIVGQALKKLPREQVVVETKCGIVWERKGSLFNKVGD
                     RQLYKNLSPESIREEVEASLQRLGIDYIDIYMTHWQSVPPFFTPIAETVAVLNELKAE
                     GKIRAIGAANVDADHIREYLQYGELDIIQAKYSILDRAMESELLPLCRDNGIVVQVYS
                     PLEQGLLTGTITRDYVPGGARANKVWFQRENMLKVIDMLEQWQPLCARYQCTIPTLAL
                     AWILKQSDLISILSGATAPEQVRENVAALNINLSDADATLMREMAEALER"
     gene            complement(41311..42258)
                     /locus_tag="IRB70_000941"
     CDS             complement(41311..42258)
                     /locus_tag="IRB70_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416286.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate kinase family protein"
                     /protein_id="HBC0630889.1"
                     /translation="MDNLDVICIGAAIVDIPLQPVSKNIFDVDSYPLERIAMTTGGDA
                     INEATIISRLGHRTALMSRIGKDAAGQFILDHCRKENIDIQSLKQDVSIDTSINVGLV
                     TEDGERTFVTNRNGSLWKLNIDDVDFSRFSQAKLLSLASIFNSPLLDGKALTEIFTQA
                     KARQMIICADMIKPRLNETLDDICEALSYVDYLFPNFAEAKLLTGKETLDEIADCFLA
                     CGVKTVVIKTGKDGCFIKRGDMTMKVPAVAGITAIDTIGAGDNFASGFIAALLEGKNL
                     RECARFANATAAISVLSVGATTGVKNRKLVEQLLEEYEG"
     gene            complement(42263..43099)
                     /locus_tag="IRB70_000942"
     CDS             complement(42263..43099)
                     /locus_tag="IRB70_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBC0630890.1"
                     /translation="MLADIRYWENDATNKHYAIAHFNVWNAEMLMGVIDAAEEAKSPV
                     IISFGTGFVGNTSFEDFSHMMVSMAKKATVPVITHWDHGRSMEIIHNAWTHGMNSLMR
                     DASAFDFEENIRLTKEAVDFFHPLGIPVEAELGHVGNETVYEEALAGYHYTDPDQAAE
                     FVERTGCDSLAVAIGNQHGVYTSEPQLNFEVVKRVRDAVSVPLVLHGASGISDADIKT
                     AISLGIAKINIHTELCQAAMVAVKENQDQPFLHLEREVRKAVKERALEKIKLFGSDGK
                     AE"
     gene            complement(43120..44163)
                     /locus_tag="IRB70_000943"
     CDS             complement(43120..44163)
                     /locus_tag="IRB70_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent alcohol dehydrogenase"
                     /protein_id="HBC0630891.1"
                     /translation="MKNSKAILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVH
                     GFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVRKFKAGDRVNIEPGVPCGHCRYCL
                     EGKYNICPDVDFMATQPNYRGALTHYLCHPESFTYKLPDNMDTMEGALVEPAAVGMHA
                     AMLADVKPGKKIIILGAGCIGLMTLQACKCLGATDIAVVDVLEKRLTMAEQLGATVVI
                     NGAKEDTIARCQQFTEEMGADIVFETAGSAVTVKQAPYLVMRGGKIMIVGTVPGDSAI
                     NFLKINREVTIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFEESVNN
                     KRDIIKGVIKISD"
     gene            complement(44180..45558)
                     /locus_tag="IRB70_000944"
                     /pseudo
     CDS             complement(44180..45558)
                     /locus_tag="IRB70_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416289.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
     gene            complement(45585..46658)
                     /locus_tag="IRB70_000945"
     CDS             complement(45585..46658)
                     /locus_tag="IRB70_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBC0630892.1"
                     /translation="MKALARFGKAFGGYKMIDVPQPICGPEDVVIEIKAAAICGADMK
                     HYNVDSGSDEFNSIRGHEFAGCIAQVGEKVKDWKVGQRVVSDNSGHVCGVCPACEQGD
                     FLCCTENHLGLDNNTWGGGFSKYCLVPGEILKIHRHALWEIPDGVDYEDAAVLDPICN
                     AYKSIAQQSKFLPGQDVVVIGTGPLGLFSVQMARIMGAVNIVVVGLQEDVAVRFPVAK
                     ELGATAVVNGSTEDVVARCQQICGKDNLGLVIECSGANIALKQAIEMLRPNGEVVRVG
                     MGFKPLDFSINDITAWNKSIIGHMAYDSTSWRNALRLLASGAIKVKPMITHRIGLSQW
                     REGFDAMVDKTAIKVIMTYDFDE"
     gene            complement(47028..47300)
                     /locus_tag="IRB70_000946"
     CDS             complement(47028..47300)
                     /locus_tag="IRB70_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310513.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaC family protein"
                     /protein_id="HBC0630893.1"
                     /translation="MNLDDIINSMTPEVYQRLSTAVELGKWPDGVALTEEQKENCLQL
                     VMLWQARNNTEAQHMTIDTNGQMVMKSKQQLKEDFGISAKPIAMFK"
     gene            complement(47342..47755)
                     /gene="msrB"
                     /locus_tag="IRB70_000947"
     CDS             complement(47342..47755)
                     /gene="msrB"
                     /locus_tag="IRB70_000947"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBC0630894.1"
                     /translation="MANKPSAEELKKNLSEMQFYVTQNHGTEPPFTGRLLHNKRDGVY
                     HCLICDAPLFHSQTKYDSGCGWPSFYEPVSEESIRYIKDLSHGMQRIEIRCGNCDAHL
                     GHVFPDGPQPTGERYCVNSASLRFTDGENGEEING"
     gene            48097..49092
                     /gene="gapA"
                     /locus_tag="IRB70_000948"
     CDS             48097..49092
                     /gene="gapA"
                     /locus_tag="IRB70_000948"
                     /EC_number="1.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006322611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBC0630895.1"
                     /translation="MTIKVGINGFGRIGRIVFRAAQKRSDIEIVAINDLLDADYMAYM
                     LKYDSTHGRFDGTVEVKDGHLIVNGKKIRVTAERDPANLKWDEVGVDVVAEATGLFLT
                     DETARKHITAGAKKVVMTGPSKDNTPMFVKGANFDKYAGQDIVSNASCTTNCLAPLAK
                     VINDNFGIIEGLMTTVHATTATQKTVDGPSHKDWRGGRGASQNIIPSSTGAAKAVGKV
                     LPELNGKLTGMAFRVPTPNVSVVDLTVRLEKAATYEQIKAAVKAAAEGEMKGVLGYTE
                     DDVVSTDFNGEVCTSVFDAKAGIALNDNFVKLVSWYDNETGYSNKVLDLIAHISK"
     gene            49176..50060
                     /locus_tag="IRB70_000949"
     CDS             49176..50060
                     /locus_tag="IRB70_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707334.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-hexose-6-phosphate mutarotase"
                     /protein_id="HBC0630896.1"
                     /translation="MIKKIFALPVIEQISPVLSRRKLDELDLIVVDHPQVKASFALQG
                     AHLLSWKPAGEEEVLWLSNNTPFKNGVAIRGGVPVCWPWFGPAAQQGLPAHGFARNLP
                     WTLKSHREDADGVALTFELTQSEETKKFWPHDFTLLAHFRVGKACEIDLEAHGEFETT
                     SALHTYFNVGDITKVSVSGLGDRFIDKVNDAKEDVLTDGIQTFPDRTDRVYLNPQDCS
                     VINDEALNRIIAVGHQHHLNVVGWNPGPALSVSMGDMPDDGYKTFVCVETAYASETQK
                     VTKEKPAHLAQSIRVAKR"
     gene            complement(50111..50965)
                     /gene="yeaE"
                     /locus_tag="IRB70_000950"
     CDS             complement(50111..50965)
                     /gene="yeaE"
                     /locus_tag="IRB70_000950"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal reductase YeaE"
                     /protein_id="HBC0630897.1"
                     /translation="MQQKMIQFSGDVSLPAIGQGTWYMGEDASQRKTEVAALRAGIEL
                     GLTLIDTAEMYADGGAEKVVGEALIGLRDNVFLVSKVYPWNAGGQKAINACEASLRRL
                     NSDYLDLYLLHWSGSFAFEETVAAMEKLIAQGKIRRWGVSNLDYADMQELWQLPGGNQ
                     CATNQVLYHLGSRGIEYDLLPWCQKQQMPVMAYSPLAQAGRLRNGLLKNAVVNEIAHA
                     HNISAAQVLLAWVISHQGVMAIPKAATIAHVQQNAAVLEVELSSAELAMLDKAYPAPK
                     GKTALDMV"
     gene            complement(51055..51801)
                     /gene="mipA"
                     /locus_tag="IRB70_000951"
     CDS             complement(51055..51801)
                     /gene="mipA"
                     /locus_tag="IRB70_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="scaffolding protein MipA"
                     /protein_id="HBC0630898.1"
                     /translation="MTKLKLLALGVLIATSAGVAHAEGKFSLGAGVGVVEHPYKDYDT
                     DVYPVPVINYEGDNFWFRGLGGGYYLWNDATDKLSITAYWSPLYFKAKDSGDHQMRHL
                     DDRKSTMMAGLSYAHFTQYGYLRTTLAGDTLDNSNGIIWDMAWLYRYTNGGLTVTPGI
                     GVQWNSENQNEYYYGVSRKESARSGLRGYNPNDSWSPYLELSASYNFLGDWSVYGTAR
                     YTRLSDEVTDSPMVDKSWTGLISTGITYKF"
     gene            52237..54171
                     /gene="yeaG"
                     /locus_tag="IRB70_000952"
     CDS             52237..54171
                     /gene="yeaG"
                     /locus_tag="IRB70_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YeaG"
                     /protein_id="HBC0630899.1"
                     /translation="MNIFDHYRQRYEAAKDEEFTLQEFLTTCRQDRSAYANAAERLLM
                     AIGEPVMVDTAQEPRLSRLFSNRVIARYPAFEEFYGMEDAIEQIVSYLKHAAQGLEEK
                     KQILYLLGPVGGGKSSLAERLKSLMQLVPIYVLSANGERSPVNDHPFCLFNPQEDAQI
                     LEKEYGIPRRYLGTIMSPWAAKRLHEFGGDITKFRVVKVWPSILQQIAIAKTEPGDEN
                     NQDISALVGKVDIRKLEHYAQNDPDAYGYSGALCRANQGIMEFVEMFKAPIKVLHPLL
                     TATQEGNYNGTEGISALPFNGIILAHSNESEWVTFRNNKNNEAFLDRVYIVKVPYCLR
                     ISEEIKIYEKLLNHSELTHAPCAPGTLETLSRFSILSRLKEPENSSIYSKMRVYDGES
                     LKDTDPKAKSYQEYRDYAGVDEGMNGLSTRFAFKILSRVFNFDHVEVAANPVHLFYVL
                     EQQIEREQFPQEQAERYLEFLKGYLIPKYAEFIGKEIQTAYLESYSEYGQNIFDRYVT
                     YADFWIQDQEYRDPDTGQLFDRESLNAELEKIEKPAGISNPKDFRNEIVNFVLRARAN
                     NSGRNPNWTSYEKLRTVIEKKMFSNTEELLPVISFNAKTSTDEQKKHDDFVDRMMEKG
                     YTRKQVRLLCEWYLRVRKSS"
     gene            54284..55567
                     /locus_tag="IRB70_000953"
     CDS             54284..55567
                     /locus_tag="IRB70_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeaH/YhbH family protein"
                     /protein_id="HBC0630900.1"
                     /translation="MTWFIDRRLNGKNKSMVNRQRFLRRYKAQIKQSISEAINKRSVT
                     DVDSGESVSIPTEDISEPMFHQGRGGLRHRVHPGNDHFVQNDRIERPQGGGGGSGSGQ
                     GQASQDGEGQDEFVFQISKDEYLDLLFEDLALPNLKQNQQRQLTEYKTHRAGYTANGV
                     PANISVVRSLQNSLARRTAMTAGKRRELHALEEHLTIISNSEPAQLLEEERLRKEIAE
                     LRAKIERVPFIDTFDLRYKNYEKRPDPSSQAVMFCLMDVSGSMDQSTKDMAKRFYILL
                     YLFLSRTYKNVEVVYIRHHTQAKEVDEHEFFYSQETGGTIVSSALKLMDEVVKERYNP
                     AQWNIYAAQASDGDNWADDSPLCHEILAKKILPVVRYYSYIEITRRAHQTLWREYEHL
                     QSTFDNFAMQHIRDQDDIYPVFRELFHKQNATAKD"
     gene            55714..57189
                     /locus_tag="IRB70_000954"
     CDS             55714..57189
                     /locus_tag="IRB70_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBC0630901.1"
                     /translation="MIRSTRISLGLFFNYFLSSTKIDPGQNYISLPSIKSSTHIALLF
                     MASMGTQKLKAQGFFIFSLLLTLILFCITTLYNENTNVKLIPQMNYLMVVVALFFLNA
                     VIFLFMLMKYFTNKQILPTLILSLAFLSGLIYLVETIVIIHKPINGSTLIQTKSNDVS
                     IFYIFRQLSFICLTSLALFCYGKDNILDNNKKKTGILLLALIPFLVFPLLAHNLSSYN
                     ADYSLYVVDYCPDNHTATWGINYTKILVCLWAFLLFFIIMRTRLASELWPLIALLCLA
                     SLCCNLLLLTLDEYNYTVWYISRGIEVSSKLFVVSFLIYNIFQELQLSSKLAVHDVLT
                     NIYNRRYFFNSVESLLSRPVVKDFCVMLVDINQFKRINAQWGHRVGDKVLVSIVDIIQ
                     QSIRPDDILARLEGEVFGLLFTELNSAQAKIIAERMRKNVELLTGFSNRYDVPEQMTI
                     SIGTVFSTGDTHNISLVMTEADKALREAKSEGGNKVIIHHI"
     gene            57370..58860
                     /locus_tag="IRB70_000955"
     CDS             57370..58860
                     /locus_tag="IRB70_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416300.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBC0630902.1"
                     /translation="MKLHHRMLRHFIAASVIVLTSSFLIFELVASDRAMSAYLRYIVQ
                     RADSSFLYDKYQNQSIAAHVMRALAAEQSEVSPEQRRAICEAFESANNTHGLNLTAHK
                     YPGLRGTLQTASTDCDTIVEAAALLPAFDQAVEGNRHQDDYGSGLGMAEEKFHYYLDL
                     NDRYVYFYEPVNVEYFAMNNWSFLQSGSIGIDRKDIEKVFTGRTVLSSIYQDQRTKQN
                     VMSLLTPVYVAGQLKGIVLLDINKNNLRNIFYTHDRPLLWRFLNVTLTDTDSGRDIII
                     NQSEDNLFQYVSYVHDLPGGIRVSLSIDILYFITSSWKSVLFWILTALILLNMVRMHF
                     RLYQNVSRENISDAMTGLYNRKILTPELEQRLQKLVQSGSSVMFIAIDMDKLKQINDT
                     LGHQEGDLAITLLAQAIKQSIRKSDYAIRLGGDEFCIILVDSTPQIAAQLPERIEKRL
                     QHIAPQKEIGFSSGIYAMKENDTLHDAYKASDERLYVNKQNKNSRS"
     gene            58903..59406
                     /gene="yeaK"
                     /locus_tag="IRB70_000956"
     CDS             58903..59406
                     /gene="yeaK"
                     /locus_tag="IRB70_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mischarged aminoacyl-tRNA deacylase"
                     /protein_id="HBC0630903.1"
                     /translation="MTEMAKGSVTHQRLIALLSQEGANFRVVTHEAVGKCEAVSEIRG
                     TALGQGAKALVCKVKGNGVNQHVLAILAADQQADLSQLASHIGGLRASLASPAEVDEL
                     TGCVFGAIPPFSFHPKLKLVADPLLFERFDEIAFNAGMLDKSVILKTADYLRIAQPEL
                     VNFRRTA"
     gene            complement(59407..59511)
                     /locus_tag="IRB70_000957"
     CDS             complement(59407..59511)
                     /locus_tag="IRB70_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416302.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630904.1"
                     /translation="MNDQMFVETLIITSSFFAIAVVLVLSVLLIERTG"
     gene            59681..60127
                     /locus_tag="IRB70_000958"
     CDS             59681..60127
                     /locus_tag="IRB70_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBC0630905.1"
                     /translation="MFDVTLLILLGLAALGFISHNTTVAVSILVLIIVRVTPLSTFFP
                     WIEKQGLSIGIIILTIGVMAPIASGTLPPSTLIHSFLNWKSLVAIAVGVIVSWLGGRG
                     VTLMGSQPQLVAGLLVGTVLGVALFRGVPVGPLIAAGLVSLIVGKQ"
     gene            complement(60084..60905)
                     /gene="nimR"
                     /locus_tag="IRB70_000959"
     CDS             complement(60084..60905)
                     /gene="nimR"
                     /locus_tag="IRB70_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NimR"
                     /protein_id="HBC0630906.1"
                     /translation="MMHRLNLNGYEPDRHHEAAVAFCIHAGTDELTSPVHQHRKGQLI
                     LALHGAITCTVENALWMVPPQYAVWIPGGVEHSNQVTANAELCFLFIEPSAVTMPTTC
                     CTLKISPLCRELILTLANRTTTQRAEPMTRRLIQVLFDELPQQPQQQLHLPVSSHPKI
                     RAMVEMMAKEPVEWGSLGQWARFFAMSERNLARLIVKETGLSFRQWRQQLQLIMALQG
                     LVKGDTVQKVAHTLGYDSTTAFITMFKKGLGQTPGRYIAGLTTVSPQSAKPDPRQ"
     gene            61002..62183
                     /gene="nimT"
                     /locus_tag="IRB70_000960"
     CDS             61002..62183
                     /gene="nimT"
                     /locus_tag="IRB70_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-nitroimidazole transporter"
                     /protein_id="HBC0630907.1"
                     /translation="MTCSTSLSGKNRIVLIAGILMIATTLRVTFTGAAPLLDTIRSAY
                     SLTTAQTGLLTTLPLLAFALISPLAAPVARRFGMERSLFAALLLICAGIAIRSLPSPY
                     LLFGGTAVIGGGIALGNVLLPGLIKRDFPHSVARLTGAYSLTMGAAAALGSAMVVPLA
                     LNGFGWRGALLMLMCFPLLALFLWLPQWRSQQHANLSTSRALHTRGIWRSPLAWQVTL
                     FLGINSLVYYVIIGWLPAILISHGYSEAQAGSLHGLLQLATAAPGLLIPLFLHHVKDQ
                     RGIAAFVALMCAVGAVGLCFMPAHAITWTLLFGFGSGATMILGLTFIGLRASSAHQAA
                     ALSGMAQSVGYLLAACGPPLMGKIHDANGDWSVPLMGVAILSLLMAIFGLCAGRDKEI
                     R"
     gene            62238..62585
                     /locus_tag="IRB70_000961"
     CDS             62238..62585
                     /locus_tag="IRB70_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 domain-containing protein"
                     /protein_id="HBC0630908.1"
                     /translation="MNIQCKRVYDPAEQSDGYRVLVDRLWPRGIKKTDLALDEWDKEI
                     TPSTELRKAFHGEVVDFATFREQYLAELAQHEQEGKRLANIAKKQPLTLLYSAKNTTQ
                     NHALVLADWLRSL"
     gene            complement(62607..62861)
                     /gene="yoaF"
                     /locus_tag="IRB70_000962"
     CDS             complement(62607..62861)
                     /gene="yoaF"
                     /locus_tag="IRB70_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF333 domain-containing lipoprotein YoaF"
                     /protein_id="HBC0630909.1"
                     /translation="MKIISFVLPCLLVLAGCSTPSQPEAPKPPQIGMANPASVYCQQK
                     GGTLIPVQTAQGVSNNCKLPGGETIDEWALWRRDHPAGEK"
     gene            63044..64069
                     /gene="dgcP"
                     /locus_tag="IRB70_000963"
     CDS             63044..64069
                     /gene="dgcP"
                     /locus_tag="IRB70_000963"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416308.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcP"
                     /protein_id="HBC0630910.1"
                     /translation="MSDQIIARVSQSLAKEQSLESLVRQLLEMLEMVTDMESTYLTKV
                     DVEARLQHIMFARNSQKMHIPENFTVSWDYSLCKRAIDENCFFSDEVPDRWGDCIAAR
                     NLGITTFLSTPIHLPDGSFYGTLCAASSEKRQWSERAEQVLQLFAGLIAQYIQKEALV
                     EQLREANAALIAQSYTDSLTGLPNRRAIFENLTTLFSLARHLNHKIMIAFIDLDNFKL
                     INDRFGHNSGDLFLIQVGERLNTLQQNGEVIGRLGGDEFLVVSLNNENTDISSLRERI
                     QQQIRGEYHLGDVDLYYPGASLGIVEVDPETTDADSALHAADIAMYQEKKHKQKTPFV
                     AHPALHS"
     gene            64102..64200
                     /locus_tag="IRB70_000964"
     CDS             64102..64200
                     /locus_tag="IRB70_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaK family small membrane protein"
                     /protein_id="HBC0630911.1"
                     /translation="MRIGIIFPGVIFITAVVFLAWFFIGGYAAPGA"
     gene            64203..64277
                     /gene="yoaJ"
                     /locus_tag="IRB70_000965"
     CDS             64203..64277
                     /gene="yoaJ"
                     /locus_tag="IRB70_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YoaJ"
                     /protein_id="HBC0630912.1"
                     /translation="MKKTTIIMMGVAIIVVLGTELGWW"
     gene            complement(64336..64584)
                     /locus_tag="IRB70_000966"
     CDS             complement(64336..64584)
                     /locus_tag="IRB70_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBC0630913.1"
                     /translation="MGILSWIIFGLIAGILAKWIMPGKDGGGFFMTILLGIVGAVVGG
                     WISTLFGFGKVDGFNFGSFVVAVIGAIVVLFIYRKIKS"
     gene            complement(64732..64914)
                     /locus_tag="IRB70_000967"
     CDS             complement(64732..64914)
                     /locus_tag="IRB70_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1869 domain-containing protein"
                     /protein_id="HBC0630914.1"
                     /translation="MGKATYTVTVTNNSNGVSVDYETETPMTLLVPEVAAEVIKDLVN
                     TVRSYDTENEHDVCGW"
     gene            complement(64918..65277)
                     /gene="yeaR"
                     /locus_tag="IRB70_000968"
     CDS             complement(64918..65277)
                     /gene="yeaR"
                     /locus_tag="IRB70_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1971 domain-containing protein"
                     /protein_id="HBC0630915.1"
                     /translation="MLQIPQNYIHTRSTPFWNKQTAPAGIFERHLDKGTRPGVYPRLS
                     VMHGAVKYLGYADEHSAEPDQVILIEAGQFAVFPPEKWHNIEAMTDDTYFNIDFFVAP
                     EVLMEGAQQRKVIHNGK"
     gene            complement(65450..66088)
                     /gene="leuE"
                     /locus_tag="IRB70_000969"
     CDS             complement(65450..66088)
                     /gene="leuE"
                     /locus_tag="IRB70_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine efflux protein LeuE"
                     /protein_id="HBC0630916.1"
                     /translation="MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVSSGMKGGY
                     LAACGVFIGDAVLMFLAWAGVATLIKTTPILFNIVRYLGAFYLLYLGSKILYATLKGK
                     NNEAKSDEPQYGAIFKRALILSLTNPKAILFYVSFFVQFIDVNAPHTGISFFILATTL
                     ELVSFCYLSFLIISGAFVTQYIRTKKKLAKVGNSLIGLMFVGFAARLATLQS"
     gene            complement(66215..67138)
                     /gene="dmlR"
                     /locus_tag="IRB70_000970"
     CDS             complement(66215..67138)
                     /gene="dmlR"
                     /locus_tag="IRB70_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310535.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DmlR"
                     /protein_id="HBC0630917.1"
                     /translation="MNNLPLLNDLRVFMLVARRAGFAAVAEELGVSPAFVSKRIALLE
                     QTLNVVLLHRTTRRVTITEEGERIYEWAQRILQDVGQMMDELSDVRQVPQGMLRIISS
                     FGFGRQVVAPALSALAKAYPQLELRFDVEDRLVDLVNEGVDLDIRIGDDIAPNLIARK
                     LATNYRILCASPEFIAQHGAPKHLTDLSALPCLVIKERDHPFGVWQLRNKEGHHAIKV
                     TGPLSSNHGEIVHQWCLDGQGIALRSWWDVSENIASGHLVQVLPEYYQPANVWAVYVS
                     RLATSAKVRITVEFLRQYFAEHYPNFSLEHA"
     gene            67241..68326
                     /gene="dmlA"
                     /locus_tag="IRB70_000971"
     CDS             67241..68326
                     /gene="dmlA"
                     /locus_tag="IRB70_000971"
                     /EC_number="1.1.1.83"
                     /EC_number="1.1.1.85"
                     /EC_number="1.1.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional
                     D-malate/3-isopropylmalate/tartarate dehydrogenase"
                     /protein_id="HBC0630918.1"
                     /translation="MMKTIRIAAIPGDGIGKEVLPEGIRVLKAAAERWGFALSFEQME
                     WASCEYYSHHGKMMPDDWHEQLSRFDAIYFGAVGWPDTVPDHISLWGSLLKFRREFDQ
                     YVNLRPVRLFPGVPCPLAGKQPGDIDFYVVRENTEGEYSSLGGRVNEGTEHEVVIQES
                     VFTRRGVDRILRYAFELAQSRPRKTLTSATKSNGLAISMPYWDERVEAMAENYPEICW
                     DKQHIDILCARFVMQPERFDVVVASNLFGDILSDLGPACTGTIGIAPSANLNPERTFP
                     SLFEPVHGSAPDIYGKNIANPIATIWAGAMMLDFLGNGDERFQQAHNGILAAIEEVIT
                     HGPKTPDMKGNATTPQVADAICKIILR"
     gene            68577..70187
                     /gene="yeaV"
                     /locus_tag="IRB70_000972"
     CDS             68577..70187
                     /gene="yeaV"
                     /locus_tag="IRB70_000972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310537.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter YeaV"
                     /protein_id="HBC0630919.1"
                     /translation="MMSNVKKKDVPLISISLVAILFIAAALSLFPQQSADAANAIYTF
                     VTRTLGSAVQVLVLLAMGLVIYLATSKYGNIRLGEGKPEYSTLSWLFMFICAGLGSST
                     LYWGVAEWAYYYQTPGLNIAPRSQQALEFSVPYSFFHWGISAWATYTLASLIMAYHFH
                     VRKNKGLSLSGIIAAITGVRPQGPWGKLVDLMFLIATVGALTISLVVTAATFTRGLSA
                     LTGLPDNFTVQAFVILLSGGIFCLSSWIGINNGLQRLSKMVGWGAFLLPLLVLIVGPT
                     EFITNSIINAIGLTTQNFLQMSLFTDPLGDGSFTRNWTVFYWLWWISYTPGVAMFVTR
                     VSRGRKIKEVIWGLILGSTVGCWFFFGVMESYAIHQFINGVINVPQVLETLGGETAVQ
                     QVLMSLPAGKLFLAAYLGVMIIFLASHMDAVAYTMAATSTRNLQEGDDPDRGLRLFWC
                     VVITLIPLSILFTGASLETMKTTVVLTALPFLVILLVKVGGFIRWLKQDYADIPAHQV
                     EHYLPQTPVEALEKTPVLPAGTVFKGDN"
     gene            70219..71343
                     /gene="yeaW"
                     /locus_tag="IRB70_000973"
     CDS             70219..71343
                     /gene="yeaW"
                     /locus_tag="IRB70_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaW"
                     /protein_id="HBC0630920.1"
                     /translation="MSNLSPDFILPENFCANPQEAWTIPARFYTDQNAFEHEKENVFA
                     KSWICVAHSSELANANDYVTREIIGESIVLVRGRDKVLRAFYNVCPHRGHQLLSGEGK
                     AKNVITCPYHAWAFKLDGNLAHARNCENVANFDSDKAQLVPVRLEEYAGFVFINMDPN
                     ATSVEDQLPGLGAKVLEACPEVHDLKLAARFTTRTPANWKNIVDNYLECYHCGPAHPG
                     FSDSVQVDRYWHTMHGNWTLQYGFAKPSEQSFKFEEGTDAAFHGFWLWPCTMLNVTPI
                     KGMMTVIYEFPVDSETTLQNYDIYFTNEELTDEQKSLIEWYRDVFRPEDLRLVESVQK
                     GLKSRGYRGQGRIMADSSGSGISEHGIAHFHNLLAQVFKD"
     gene            71399..72364
                     /gene="yeaX"
                     /locus_tag="IRB70_000974"
     CDS             71399..72364
                     /gene="yeaX"
                     /locus_tag="IRB70_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine monooxygenase subunit YeaX"
                     /protein_id="HBC0630921.1"
                     /translation="MSDYQMFEVHVNQIEPLTEQVKRFTLVATDGKPLPTFTGGSHVI
                     VQMSDGDNEYSNAYSLLSSPHDTSCYQIAVRLEEHSRGGSRFLHQQVKVGDRLTISTP
                     NNLFALIPSARKHLFIAGGIGITPFLSHLAELQYSDVDWQLHYCSRNPESCAFRDELV
                     QHPQAEKVHFHHSSTGTRLELARLLADIEPGTHVYTCGPEALNEEVRSEAARLDIAAD
                     TMHFEQFAIEDKTGDAFTLVLARSGKEFVVPEEMTILQVIENNKAAKVECLCREGVCG
                     TCETAILEGEADHRDQYFSDEERASQQSMLICCSRAKGKRLVLDL"
     gene            complement(72418..73533)
                     /gene="rnd"
                     /locus_tag="IRB70_000975"
     CDS             complement(72418..73533)
                     /gene="rnd"
                     /locus_tag="IRB70_000975"
                     /EC_number="3.1.13.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310540.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease D"
                     /protein_id="HBC0630922.1"
                     /translation="MITTDDALASLCEAVRAFPAIALDTEFVRTRTYYPQLGLIQLFD
                     GEHLALIDPLGISDWSPLKAILRDPSITKFLHAGSEDLEVFLNVFGELPQPLIDTQIL
                     AAFCGRPMSWGFASMVEEYSGVTLDKSESRTDWLARPLTERQCEYAAADVWYLLPITA
                     KLMVETEASGWLPAALDECRLMQMRRQEVVAPEDAWRDITNAWQLRTRQLACLQLLAD
                     WRLRKARERDLAVNFVVREEHLWSVARYMPGSLGELDSLGLSGSEIRFHGKTLLALVE
                     KAQTLPEEALPQPMLNLMDMPGYRKAFKAIKSLITDVSETHKISAELLASRRQINQLL
                     NWHWKLKPQNNLPELISGWRGELMAEALHNLLQEYPQ"
     gene            complement(73615..75300)
                     /gene="fadD"
                     /locus_tag="IRB70_000976"
     CDS             complement(73615..75300)
                     /gene="fadD"
                     /locus_tag="IRB70_000976"
                     /EC_number="6.2.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain-fatty-acid--CoA ligase FadD"
                     /protein_id="HBC0630923.1"
                     /translation="MKKVWLNRYPADVPTEINPDRYQSLVDMFEQSVARYADQPAFVN
                     MGEVMTFRKLEERSRAFAAYLQQGLGLKKGDRVALMMPNLLQYPVALFGILRAGMIVV
                     NVNPLYTPRELEHQLNDSGASAIVIVSNFAHTLEKVVDKTAVQHVILTRMGDQLSTAK
                     GTVVNFVVKYIKRLVPKYHLPDAISFRSALHSGYRMQYVKPELVPEDLAFLQYTGGTT
                     GVAKGAMLTHRNMLANLEQVNATYGPLLHPGKELVVTALPLYHIFALTINCLLFIELG
                     GQNLLITNPRDIPGLVKELAKYPFTAITGVNTLFNALLNNKEFQQLDFSSLHLSAGGG
                     MPVQQVVAERWVKLTGQYLLEGYGLTECAPLVSVNPYDIDYHSGSIGLPVPSTEAKLV
                     DDDDNEVPPGQPGELCVKGPQVMLGYWQRPDATDEIIKNGWLHTGDIAVMDEEGFLRI
                     VDRKKDMILVSGFNVYPNEIEDVVMQHPGVQEVAAVGVPSGSSGEAVKIFVVKKDPSL
                     TEESLVTFCRRQLTGYKVPKLVEFRDELPKSNVGKILRRELRDEARGKVDNKA"
     gene            complement(75505..76086)
                     /gene="yeaY"
                     /locus_tag="IRB70_000977"
     CDS             complement(75505..76086)
                     /gene="yeaY"
                     /locus_tag="IRB70_000977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Slp family lipoprotein YeaY"
                     /protein_id="HBC0630924.1"
                     /translation="MAVQKNVIKGILAGTFALMLSGCVTVPDAIKGSSPTPQQDLVRV
                     MSAPQLYVGQEARFGGKVVAVQNQQGKTRLEIATVPLDSGARPTLGEPSRGRIYADVN
                     GFLDPVDFRGQLVTVVGPITGTVDGKIGNTPYKFMVMQATGYKRWHLTQQVIMPPQPI
                     DPWFYGGRGWPYGYGGWGWYNPGPARVQTVVTE"
     gene            complement(76125..76820)
                     /gene="tsaB"
                     /locus_tag="IRB70_000978"
     CDS             complement(76125..76820)
                     /gene="tsaB"
                     /locus_tag="IRB70_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBC0630925.1"
                     /translation="MRILAIDTATEACSVALWNDGTVNAHFELCPREHTQRILPMVQD
                     ILTTSGTSLTDINALAYGRGPGSFTGVRIGIGIAQGLALGAELPMIGVSTLMTMAQGA
                     WRKNGATRVLAAIDARMGEVYWAEYQRDENGIWHGEETEAVLKPELVHERMQQLSGEW
                     VTVGTGWQAWPDLGKESGLALCDGEVLLPAAEDMLPIACQMFAEGKTVAVEHAEPVYL
                     RNNVAWKKLPGKE"
     gene            complement(76878..78788)
                     /locus_tag="IRB70_000979"
     CDS             complement(76878..78788)
                     /locus_tag="IRB70_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBC0630926.1"
                     /translation="MTDDFAPDGQLAKAIPGFKPREPQRQMAVAVTQAIEKGQPLVVE
                     AGTGTGKTYAYLAPALRAKKKVIISTGSKALQDQLYSRDLPTVSKALKYTGNVALLKG
                     RSNYLCLERLEQQALAGGDLPVQILSDVILLRSWSNQTVDGDISTCVSVAEDSQAWPL
                     VTSTNDNCLGSDCPMYKDCFVVKARKKAMDADVVVVNHHLFLADMVVKESGFGELIPE
                     ADVMIFDEAHQLPDIASQYFGQSLSSRQLLDLAKDITIAYRTELKDTQQLQKCADRLA
                     QSAQDFRLQLGEPGYRGNLRELLANPQIQRAFLLLDDTLELCYDVAKLSLGRSALLDA
                     AFERATLYRTRLKRLKEINQPGYSYWYECTSRHFTLALTPLSVADKFKELMAQKPGSW
                     IFTSATLSVNDDLHHFTSRLGIEQAESLLLPSPFDYSRQALLCVPRNLPQTNQPGSAR
                     QLAAMLRPIIEANNGRCFMLCTSHAMMRDLAEQFRATMTLPVLLQGETSKGQLLQQFV
                     SAGNALLVATSSFWEGVDVRGDTLSLVIIDKLPFTSPDDPLLKARMEDCRLRGGDPFD
                     EVQLPDAVITLKQGVGRLIRDADDRGVLVICDNRLVMRPYGATFLASLPPAPRTRDIA
                     RAVRFLAIPSSR"
     gene            78920..79264
                     /locus_tag="IRB70_000980"
     CDS             78920..79264
                     /locus_tag="IRB70_000980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416323.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBC0630927.1"
                     /translation="MTIVRIDAEARWSDVVIHNNTLYYTGVPENLDADAFEQTANTLA
                     QIDAVLEKQGSNKSSILDATIFLADKNDFAAMNKAWDAWVVAGHAPVRCTVQAGLMNP
                     KYKVEIKIVAAV"
BASE COUNT        19808 a        20524 c        19123 g        19854 t
ORIGIN      
        1 tagcaaaact taaccatttt aaaataaata aacaattaaa gaaaaaagtt cacttattta
       61 tagcaataga tcgtcaaagg cagctttttg ttacaggtgg tttgaatgaa tgtagcaatg
      121 aaatacaaaa tttcaggcca tgtaactccc ggcaaaaccg ggaggtacgt aatctttact
      181 cagtcacttc cccttcctgg cggatctgat ttgcccaacg ctgggcggat tcaggcacag
      241 taaacgccgg tgagcgcata aatgactccc ccatcagtac aaacgcaaca tatttgccac
      301 gcagcatcca gacatcacga aacgaatcca tctttatcgc atgttctggc ggcgcgggtt
      361 ccgtgcgtgg gacatagcta ataatctggc ggttttgctg acggagcggt ttcttcatta
      421 ctggcttcac taaacgcata ttaaaaatca gaaaaactgt agtttagccg atttagcccc
      481 tgtacgtcct gctttgcgtg tatttcataa caccgtttcc agaatagtct ccgaagcggg
      541 atctgactgg tggtctatag ttagagggtt ttttgaccaa aacagcggcc ctttcagtaa
      601 taatttaagg agacgagttc aatgtcgcaa cataacgaaa agaacccaca tcagcaccag
      661 tcaccactac acgattccag cgaagcgaaa ccggggatgg actcactggc acctgaagac
      721 ggatctcatc gtccagcggc tgaaccaaca ccgccaggtg cacaacctac cgctcctggg
      781 agcctgaaag cccctgatac gcgtaacgaa aaacttaatt ctctggaaga cgtacgcaaa
      841 ggcagtgaaa attatgcgct gaccactaat cagggcgtgc gcatcgccga cgatcaaaac
      901 tcactgcgtg ccggtaaccg tggtccaacg ctgctggaag attttattct gcgcgagaaa
      961 atcacccact ttgaccatga gcgcatcccg gaacgtattg ttcatgcacg cggatcagcc
     1021 gctcacggtt atttccagcc atataaaagt ttaagcgata tcaccaaagc ggatttcctc
     1081 tcagatccga acaaaatcac cccagtattt gtacgtttct ctaccgttca gggtggtgct
     1141 ggctctgccg ataccgtgcg tgatatccgt ggctttgcca ccaagttcta taccgaagag
     1201 ggtatttttg accttgttgg caataacacg ccaatcttct ttatccagga tgcgcataaa
     1261 ttccctgatt ttgtgcatgc ggtaaaacca gaaccacact gggcaatccc gcaggggcaa
     1321 agcgctcacg acaccttctg ggattatgtt tccctgcaac cggaaacact gcacaactta
     1381 atgtgggcga tgtcggatcg tggtatcccg cgcagctacc gcactatgga aggctttggt
     1441 attcatacct tccgtctgat taacgccgaa ggtaaagcga cgttcgtacg tttccactgg
     1501 aaaccactgg caggtaaagc ctcactcgtt tgggatgaag cacaaaaact aaccggacgt
     1561 gacccggact tccaccgccg cgagttgtgg gaagcgattg aagcaggcga ttttccggaa
     1621 tacgaactgg gcttccagtt gattcctgag gaagatgaat ttaagttcga cttcgacctt
     1681 cttgatccaa ctaaacttat cccggaagaa ctggtgcccg ttcagcgtgt cggcaaaatg
     1741 gtgctcaatc gcaatccgga taacttcttt gccgaaaacg aacaagcagc attccatcca
     1801 ggtcatattg ttcctggtct ggacttcacc aacgatcccc tgttgcaggg acgtttgttc
     1861 tcctataccg atacacaaat cagtcgtctt ggtgggccga atttccatga gattccgatt
     1921 aaccgcccga cctgccctta ccataatttc cagcgtgacg gcatgcatcg tatggggctc
     1981 gacactaacc cggcgaatta tgaaccgaac tcgatcaacg ataactggcc gcgcgaaaca
     2041 ccgccggggc cgaaacgcgg cggttttgaa tcataccagg agcgcgtgga aggcaataaa
     2101 gttcgcgagc gcagcccatc gtttggcgaa tattattccc atccgcgtct gttctggcta
     2161 agtcagacgc cattcgagca gcgccatatt gtcgatggtt tcagttttga gttaagcaaa
     2221 gtagttcgtc cgtatattcg tgagcgcgtt gttgaccagc tggcacatat tgatctcact
     2281 ctggcccagg cggtggcgaa aaatctcggt atcgagctga cggacgacca gctgaatatc
     2341 accccgcctc cggacgtcaa cggtctgaaa aaggatccat ccttaagttt gtacgccatt
     2401 cctgacggtg atgtgaaagg tcgcgtggta gcgattttac ttaatgatga agtgagatcg
     2461 gcagaccttc tggccattct caaggcgctg aaggccaaag gcgttcatgc caaactgctc
     2521 tactcccgaa tgggtgaagt gactgcggat gacggtacgg tgctgcctat agctgctaca
     2581 tttgccggag cgccttcgct gacggtcgat gcggttattg tcccttgcgg caatatcgcg
     2641 gatatcgctg acaacggcga tgccaactac tacctgatgg aagcctacaa acaccttaaa
     2701 ccgattgcgc tggcaggaga cgcgcgcaag tttaaagcaa caatcaaggt cgctgaccag
     2761 ggtgaagaag ggattgtgga agctgacagc gccgatggta gttttatgga tgaactgtta
     2821 acgctgatgg cagcacaccg cgtgtggtca cgcattccta agattgacaa aatcccggcg
     2881 taaatatgga taaggtcacg ccccctgggg agtgacctta ccaccttact tacacatcaa
     2941 gataactacc caaccgataa ccacgctcag caatcgcata tttcaacgac gctgaagtca
     3001 gcacatccag ttccgttaac cgagggaagc aataagcact ctggcgaatc gtattatcga
     3061 taaacgccgg gtggcacatc acttccagag agcgctcgcc gcgatgactg gagtcatcaa
     3121 gcacttgcag gaacagcgac tcactgatct cttcaccgta gaatgcactg ctgaatccct
     3181 gggtagtacg caggttgacc ggcaaatcaa acaccatctg acgatccgcc cgcaacgcaa
     3241 tgccctcttc tgccgcaaac ctggcaacaa tcgggaaaat ctgcgggaac atatgcacat
     3301 gatgatggct atcaagatgc gtaggtttgc gtccaaatag ctcaatgaaa cgcaaatact
     3361 gactggcaag ctcctgagta atttcttcca gcggtaaagc atcttcttct gccaactgcc
     3421 agatccattt tcccagcaca ccatcgcggg ttaaccccgg catagctgtc agaggcttgc
     3481 ccatagtaag gacaaagtgc atccctatgg tcagactcgg ttcatcacgg ctcaactgca
     3541 ccgcatggtc aatagcctgc ccattcacca gcgccgtcgt cgacgtgaca atcccattgc
     3601 gacaggcctc gataatgccg tagttctgac ctttgcttaa accaaaatca tcggcattaa
     3661 caatcagtaa gcgttccata atcagcctcg gttaatgtgc ttttttaagc tctgcgatgc
     3721 agtcggcaaa atttggcagc catttctcgt gcgccagaat catctcgcgt gccagcagct
     3781 cagcatcgcg atcggaatgc accaacggac taaggtttag cgctagtaag acatcgttaa
     3841 attctccact aagtgcggcg ttgctggcag caatctcgaa gcctttgatg gtgtgaatca
     3901 gccccatcac tttatcatcg aaatgcgtaa tgcgcggatg tggcgtcgcg ccatcgcgcc
     3961 ccagcgtaca ggtcatttct accgcccagt ctgccggaat attatcaata tgcccatgat
     4021 gcgggatatt aacgtaatgt tctgcttgct tgtcgttata gatagcgttg atcacttcgc
     4081 acgcagcatc agagtaataa gccccaccgc gctgttccag ttctttcggc ttaactttca
     4141 actccgggtt tttatacagc tcaaaaagtt gtttctcgac tttctgtact acctgcgctc
     4201 gtgcgccgcc tttgtagtat tcgcccattt caatagccag catctctttt tgcttgaagt
     4261 aataaagcaa ataagaacac ggcaacagat tcagagaacg aattaagcct tcgctaaatg
     4321 gcagttcgaa aatattttta acgccagatg cttttaactg cccggatgcc acaccatcaa
     4381 gcaattcggc aaagcgtgat ttgccattta ccagcacatc tttaatgaac accatatggt
     4441 tgaggccgaa cagatcgata gataaatcat cgctgtcttt cagcatcaga acatcgcgaa
     4501 taaacatctt catgccgatc ggaatattac acacgccgat aaagcgttta aatccggtat
     4561 gacgataaac ggcttcagtg accattcccg ccgggttagt gaaattaatc acccatgcat
     4621 tcggacaaag ttcttcgaca tcttttacga tgtcaaaaat caccggaatg gtacgcagac
     4681 ctttaaacag gccgcccgcg ccgttggttt cctgaccaag ataaccatga cttaatggaa
     4741 tacgttcatc cagttcgcgc gccggtaatt ggcctacgcg cagttgggta gtaacgaaat
     4801 cagcatcttt caatgcttcg cggcgatcca gcgttttata aagcttcatc gggacgccag
     4861 cgttatcaat catccgttgg cagagatcaa aaataatatc cagtttctct ttaccatctt
     4921 cgacatccac cagccataat tcgctgaccg gcaattcgtg ataacgctta ataaatcctt
     4981 ccagtaactc cggggtatag ctgctcccgc caccaatagt gacgactttt aatttctggc
     5041 tcataatttc tcccttcagt acagaatact gatatctggc atatctgccc ccccggacat
     5101 aaataatcca gcaacaggac agatatgtga attgtcaggt ataacgactt actgattaaa
     5161 ttcagtcaat ttcttacgat agctcttagg cgtaaaggac gttaatttct taaacgtttt
     5221 aataaacaaa ctcgggctac tataaccggc ctcaaacgca atatccgtca ctgaatagtt
     5281 ggtcatttcc agttgttttt tggcaaaatt aatacggatt tcattaataa tctgcattgg
     5341 cgttttgcca taatatcgtt gagtcgctcg cgtcaaatat tcctgtgatt tggctgacaa
     5401 cgtcaccata ttctccagtg ccgattcact aaactgctct ttatcatgca tcttttctac
     5461 cgtacttttc agccactgcg gtacatcatc aatcacctgt tcttcgcggt aatgacgtaa
     5521 acggttaatg acataaaaag taaccatctc aacaaactct tccagccctg tttcgcggaa
     5581 attcaatgaa gaaatcactg tttccacata ggtgagaaaa gcgttattgg tccggtatac
     5641 ctgcgaagct acaaagcaat aaggcaacaa cggcaggtaa tgctgctcaa aaaagcgttt
     5701 actgatccca acgttcaata tgcgcgtggc accaaactca taaaaacttt gatggtgcga
     5761 acctaacgga ataaaaacaa aatcgccccg ttccagtaac acgcgcttac cgttaatctc
     5821 ctggaaataa cgcccggtca ataccagagt aaattcataa tagtcgtgct gatgcagtcc
     5881 gctgatactc tcagttttgt tgtagataaa cacatggaag tttttgccat taaacaactg
     5941 ctgttctcgg gcagtggcaa tttccggcgc gttaatcatt ggctgcatca tcgactcctt
     6001 atgccttcag tttttcatga agctcaatta attcagtaat cagttcacgc gcaagcatgg
     6061 acgtcattaa atgatcctga gcgtggacca gcaccagact cactttcatc ttaccttcgc
     6121 ccgcatcgcc ttcaatcagt ttcgtctgta ccagatgcgc ttcattcaat gccatccgtg
     6181 actgatccat catggctttt gctgcggcaa aatcgccctg cttcgcctgt ttcagtgccg
     6241 catacgccag gctgcgcgct tgtccggagt tgatgataag ccccatcacc acttcttcca
     6301 gctcttcagc ttctgtttgc gtatcgggaa tgttatcgag atccatcata catcgttcct
     6361 ctcttttctt accggcacga ttacccgtac cggcatcgat taaaatttca gggcgttagc
     6421 gatatcttct tcgctctctt ctttatcaat cgcgttttgt gctttgttag ccaccacaac
     6481 aaagggcaga taaattaacg ttgcgatacc aaggttgaag agtgcaacca gcaatgcggc
     6541 gacgctaccg ttggtgttaa agaaggctcc cagaccggtt ggcatggtcc acggtgcaat
     6601 attggtcacc ggaggaataa tgcccatgta gtacgctgcc agggtgattg ccgccagaat
     6661 cggttgtacc agtacaaacg ggataaacat caccgggttc atgataattg gcagaccaaa
     6721 cagaatcggt tcgttaatct ggaagatgcc ggacggcagc gccagttttg ccacctgacg
     6781 ataatcagca cggcgagagg cgataaagat agccaggatc agacccaaag tcgcaccact
     6841 gccaccgagg aaaataaagg agtccagcat cggcttggcc cagatatgga aggtcttacc
     6901 ggctgccagc gccgcttcga cggaaccata ttgctgatag gtcgcgatat tttccagcgc
     6961 ccacggcgtc ataatgccgt tgtccagtgc ggtcagcgcc agcgcgccat gaataccgaa
     7021 gaaccagagc agtggaacaa agatcacata ggcccagccc accacgctac ccaacgatgc
     7081 cagtggggtt gagatggtat ccatgatgat ctgatggaag ttggtgcccc aggtattcaa
     7141 cgcccaggca ataatcccca tcacggaaag aataataaag ccgggaatta aagccgagaa
     7201 ggaacgcgat actgaagcag gtacgctatc gggcaattta atgacccaat tgcggcggac
     7261 aataaaggta aacatttctg ccaccaccag gccaataata atcccggaga tgatattcgc
     7321 cccacctaac cagtttgcgc caaccgcata ggcctcaccg acactatatg gggtgacggt
     7381 cataaatgct gcaacggata acaacccagc cgccagcgca tcgactttac gctcttctgc
     7441 cagcgccatg ccaataaaga acggtgccat taaagacatt atccctaatg ttccgttata
     7501 tacgttgccg ccaatacctt tcagaccatt aagtgtttca atggttgagg catccaggcg
     7561 aatacctaag gaataaaaaa acgacccctc cccaaagctt agaaaaacgt tgttaattaa
     7621 tacaaacatg gcccccgcaa gggttaacgg cattaagcga ataaagccat ttttgattgc
     7681 attaacgtgt ggctgctttc ctattttaac tgcaaaaggg aggagtacct tttcaagcga
     7741 tgcaataaca ttactcatag aaaaataccc ttaaaaaccg caatttaaat attgcggtat
     7801 tgatttatga aataactctt tgacgggaaa atttaaaata aattaatttg ctgcggcttt
     7861 tttaatcgct gcaaccgcag ccttaagcac gcctaaacca tcgactttgc cataaagcag
     7921 cgagtcaatt acttcaaccg gtttgttggg taacaaacgc tggatttcgg gcaacatata
     7981 agcaatctgc ggccctaata acacgacatc ggcattctga cctttttcac cagccagtgt
     8041 ttccggaaat gcttcaataa tgaccggaac ttcatatttt tctgcctgtg cgcgcatttt
     8101 tgataccagt aaagaggtag acatgcccgc agaacaaaac agataaatgt gtttcttttc
     8161 cataaaactg ccctcatcga cgattatctg tcagccagac actccgcaag ccttaacctg
     8221 cttccatgct ctgggtaact tgcgaaacca acatgacttt ttttgtggct gaaaggagta
     8281 tacggtatag acctaagcaa tagtatttct ttgaccttat aaattgtctc tccttgacct
     8341 gcggttatga ccctcttcac atttcgggca aataattcgc gaagataatt aagaactcag
     8401 gccaaaaaaa accggcgcaa tggccggttt ccgttgtaac tcaagctttc aggcgaagtg
     8461 attacttcgc agcctgtgga tcagtgtcgt attcagcaca ggtctgataa ccggagttga
     8521 tgacatgtcc ggtatcatct aacgcgacaa agtaggtttc tgctttacca tcacgttgac
     8581 ccaggatgta ggtctggcaa gtaccacgag catggatcat gctcacttca gacgaaggtt
     8641 tacccgcaat ttgtgcaacc tgcgcccggc tcatgccttt tttgacgtct ttcaccacag
     8701 gctgtacaaa ctggtctttg gtacgatcat aagccgtaca acccgccagc atggttaata
     8761 ccgccgctgc actcagaatt cctgccatat tcttgttcat attccgtcct cttgtttatc
     8821 agcgtgttag ataagcctgg aatacattgg gcgctttttc aagcccgtga acgaaacggc
     8881 tccgctttca gaggattcct gtatgacgtt ttaaccacca ttcagcccgc tgtcgcttgt
     8941 cgtttcagta gcaacgggtt agctttaagg aagttttgtc ttttctgtct ggaggggttc
     9001 aatgacattg caacaacaaa taataaaggc gctgggcgca aaaccgcaga ttaatgctga
     9061 agaggaaatt cgtcgtagtg tcgattttct gaaaagctac ctgcaaactt atccgttcat
     9121 taaatcactg gtgctcggga tcagcggcgg tcaggactcc acgcttgccg gtaagctgtg
     9181 ccagatggcg attaatgagc tgcgccagga aaccggcaac gaatcactgc aatttattgc
     9241 cgtacgcctg ccctatggtg ttcaggccga cgaacaagat tgccaggatg ccattgcctt
     9301 tattcaaccg gatcgcgtat taaccgttaa tatcaagggc gcggtattgg ccagcgaaca
     9361 ggcgctgcgc gaagcgggta ttgaattaag tgattttgtc cgtggcaatg aaaaagcgcg
     9421 tgagcggatg atagtacaat atagcattgc gggtatgacc agcggtgtcg tggtgggcac
     9481 cgatcatgca gcagaagcca ttaccggatt cttcactaaa tatggtgacg gcggtacgga
     9541 cattaatcca ctgtatcgtc tcaacaaacg tcagggtaaa cagttactgg cagcattagg
     9601 ttgcccggaa cacctttata agaaagcccc aactgccgat ctggaagatg atcgcccttc
     9661 tctgccagat gaagtggcac tcggcgtgac ctatgacaat atcgacgact atctggaagg
     9721 gaaaaaccta cctgaacagg tcgccagaac aatagagaac tggtatctga aaaccgaaca
     9781 taaacgccgt ccgccaatta ccgttttcga tgatttctgg aagaagtaat aatttgcaca
     9841 tattggtttg tgcgaaaaag agtactttgt tcacgccgga tgcggcgtga acgccttatt
     9901 cgacctacaa aactatgcaa attcaatata ttgcatgagt cgaataggac tgacaggcgt
     9961 agcacgtctc acggtgtaac ctttgtcatc gccccgcctc ttttttaatc gctccccgcc
    10021 tgttacactg gatagataac cagcactcgg agtcaacagt ggtacggcgt ttaacttctc
    10081 cgcggctcga atttgaagct gcggcaattt atgaatatcc cgaacattta cgttcattcc
    10141 ttaatgactt acccacccga ccaggggtgt atctgtttca tggcgaaagt gacaccatgc
    10201 cgctctatat cggcaaaagc attaacattc gcagccgcgt cctttctcat ttacgtaccc
    10261 cggatgaagc cgccatgcta cggcaatccc ggcgaattag ctggatttgc accgcaggcg
    10321 aaatcggcgc tctgctcctt gaagcgcgat taatcaaaga acaacagcca ctgtttaata
    10381 aacgcttgcg gcgaaatcgc cagctctgcg ccctgcaatt aaatgaaaag cgcgtcgatg
    10441 tggtgtatgc caaagaggtg gatttttcac gagcccccaa cctgtttggc ctgtttgcca
    10501 ataggcgcgc agctttgcaa gcattgcaga ccatcgctga tgaacaaaaa ctttgttatg
    10561 gtctgttggg actggagccg ttaagtcgcg gtcgtgcatg ttttcgttca gcgctaaaac
    10621 gttgcgccgg agcatgctgc ggtaaagaga gccatgacga tcatgcgcta cgtttgcgcc
    10681 agtctctgga acgtttacga gtagtttgtt ggccgtggaa aggtgcggtg gcgctgaaag
    10741 aacagcaccc ggaaatgact caatatcata ttattcaaaa ctggctgtgg ctgggggcgg
    10801 ttaattcgct ggaagaagcg acaatgttaa ttcggacacc cgccgggttt gatcacgacg
    10861 gttataaaat tctttgtaag ccgctgcttt ccggtaacta tgaaattact gaacttgatc
    10921 cggcgaatga ccagcgagcc agttgatttc actgaacaac agtttacctt gcggttgtaa
    10981 aagccgcagg gtgtgcctgc catcgaacca gcacgcgccc tggtcggtag tgagtagttt
    11041 atcgcccaat tgccacgccc cgttaatgac aaacactacc ccgccacgtg agccaaaggt
    11101 agtaaacgta cgttcggcaa ttctgacttt cgccttacag acatccaggc gtgtcatgat
    11161 gttgaaatcc atcgacatct gccctgccgt cagtttcgct tttaccacct ggtccgccgc
    11221 aaaggcaaaa ggctgtaacg gttttaaggt atggttaaag cggtctgtgc tttcaaggaa
    11281 catctcgccg ccttccagca acgtcactat cctttccata cctggaaaca aagaaaactc
    11341 cccattcgcc gcgatggatg caatgctggc acgccagtaa aaatcacgtt ttgccggtgg
    11401 gaaagtgcaa atttcgcgcg tttcaccggc agcatttcgc cacagattca ccgacatttt
    11461 acgcatatca aagtattcca tactcgctcc cggcccgttc ttttcattgt tatcgttcag
    11521 gtaaccgtgg atggttatcg gcaactcggg tgatttacgt tagtggcaat caggcttttt
    11581 ttgcatctgt ttgagaacaa aaaagaaaac cgccgatcct gtccaccgca ttactgcaag
    11641 gtagtggaca agaccggcgg tcttacgttt tttggctgaa agattattca gcagttgcag
    11701 gcattttacc ttttgccgct ggacgttctg tcagacgctt ctcaaaatta gcattaaatt
    11761 gctttttctg ttccggcgtc aggatgttgt aaatcttgtt ctgggtttcc atgtgcgcca
    11821 gcatgttagc tttgcgctgt tcttccattt ttgcgatctg cgcttcagct tttgctttat
    11881 cgaaggtatc gctggcaatg atgtcatgca ttgcgcggcg ttcttccagc ggcggacgtt
    11941 tcatctggtc acgctggcct ttcatgattt cgcggatctg ctgtttctgc gcgtcggtca
    12001 ggttcaggtc tttgaacatc atgtcctgat gcggaccgaa cttgcctttg tggtgcatca
    12061 tcggcttcgc gtcagccggt gctgaggtag tggtgtctgc ggcatgggcc aggttagccg
    12121 cgccaagagc cagggtagag gcaacaaaca gtgcagttaa tttacgcata ttctatatcc
    12181 ttcctttcag ttatttatta cggctttctt aagtagcgtg ccgtgttgac gagattaact
    12241 ttactgactt tagcgtcaat taatcagagc aacggtaaaa caatgaaagt gtaaaaaaca
    12301 ctttttcgcc aattatggag aaaaaaagaa aatttgatgg agagtaatga gagaatatta
    12361 caacacgatg attttgcaga gattatgaag aactataccg gatgactggt gataaataaa
    12421 gcaaataacc aggattaatc tgtattaatt tataagaaag taacttaata cccgcagaat
    12481 gatttctgcg ggtaagtatt agcttatttt ttcgagcatt aatcccgcac gtaatcccaa
    12541 cgctaccaac ggattaggga ataacacata ctctacatca tgggttacgg taaaacgttc
    12601 ctccccgtcc tgcgccagca atgttccttt ctcaaacggc ataaaattca gcgtgtcatt
    12661 tgccatatgc atttcgaagg acggcgagtg gcgagtaatt tgcgaaacca cccgataacg
    12721 gagcggcggt gttctcacga taccgacact ctcaccagat agcagcgcag caattgcgct
    12781 ggcagttact gcaaactggc gaagatcgtt ttgcccaaag ggcaacgctt tgccaagttc
    12841 cagcgtacag gccagcgcgc caaaatgtct ggcgctgaaa tgggtaaacg taccaccagg
    12901 ctcctgatgg aacaccagtg cctccagccc cgccgcaccc agccacgtca gaaatttctc
    12961 gtcccaggga atgtcgcgtt gcggtaatac accgaactgc ggatgcaagg agccacgaat
    13021 tgcggtatgt agatcaaggt gccagcgcac agattctttg ccctggtcat aaaaatcttc
    13081 caggcactgt tccagttcgc gcgcccgaca ggtttccccg ctttcagcaa atagctgcca
    13141 acgaccgcca aacattcggt tcatatcgct atggcaataa cgtttccctt gcttcagcgc
    13201 aggaggattc ccgaggatca ccagcaaccg ccaacgtaac gggatctcgc cgtgagatat
    13261 cgcgccaagc aacgcatcca gcatttccac aggtgccgtc tcattaccgt gtattcccgc
    13321 tgaaatcacc agtgcgcctt gcggtggcgt taatggcgtc agttccagca cgccatcgcc
    13381 cagccagcgc cagcgaacgc cgttgatttc tcgctcggtg ataaccggtt ttttacccgt
    13441 taatgtcaga gcaagaaaat tatccattgc cccctccctc gcgctggaac ggataaaccg
    13501 aaccgagatt cagtaattgg ctcaatacat ccagtgcttc ccgcccttcg cgcagcagtt
    13561 gcgggtcggc cagatcggca gcagtaaggc gatcgcggta gtaacgatcc acccagtcat
    13621 tgagcgcatt aaacagcgta tcgttcatca tcaccgccgg attcactgcc cggcgttctt
    13681 cttctgtcaa taccacgcgc aaccgcaggc acgccgggcc tccgccattc gccatgcttt
    13741 cacgtaaatc aaagactttt agttcgctaa tcgggttgtc agcggcaagg agttcattga
    13801 gataacccca tactccggcg tgttcccgac actcctgagg cagcaccaac atcatggaac
    13861 catcatcgcg gctcagcagt tggctgttaa acagatatgt agacaccgca tctgacacgg
    13921 aaacctgagt cgccggaact tctatcgcca taaaaccgtt cacccgcgca cgcaggtttg
    13981 ccagtaactg cacctgtcga gcgaacgcct gttgatggca aaacagcacc tggcggttac
    14041 tcacggcaat cacgtcatta tgaaaaacgc cctggtcgat aacgtccggg ttttgctggg
    14101 cgaaaatcac ctgttgggga ttcacctgat tcagccttgc caccgcctcg ctggcttcgc
    14161 gagtctgtcg cgccggataa cgggaaggcc gggtatcatt gccctcttct cgcccgtaga
    14221 caaaaagttg catacccggt tcaccgtaat gaccgccgag acgattgtgg tttgccgccc
    14281 cctcatcacc gagcaacgct acctgcggca acgccgaatg gacactaaat ttctcttcgt
    14341 tgttaaaaat cgcttttaac agcgattcag agacgggcgc ttccagcgaa cggtgaaatt
    14401 tattgttcag gttggcaacg gtgagatgca ctttgccatc cagcgtatcg gcagatggcg
    14461 cgatcgttgc cgcattggct acccacattg gcgaagcgga gctgacactg gaaagccagt
    14521 gcggtgcctg gcgtgcaact ttttccagta cctgctcatc gctaccactg aaacccaact
    14581 gacgcagcac cggaataaac gggcgctcgt gcggcgggat cacagcctgg gggaatcccg
    14641 catcggcaag ggttttcatt ttcagtaagc cctgttttgc cgccagccgc gggttagaga
    14701 tctgaaaacg gtgacgggta gaggcttcat taccaaacga caggcccgcg taatgatgcg
    14761 tcagccctac cagcccgtcg aaattgactt cccaggcgtt catcgcacca cctcatcgga
    14821 aaaatccagc ccggggttaa gtgtggcggg caatgttaac gagtccgact ccaggctcgc
    14881 catcggccag gcacaataat ctgcggcata ccaggcgctg gggcgatggt taccggaagc
    14941 gccaatgccg ccgaatggcg cggtactggc agcgccggta agcggtttat tccagttaac
    15001 aatccccgcc cgcgcctcaa gcagcagttg atcgaatttt tcccgcgcgg gggaaaccag
    15061 accgcaggag aggccaaagc gagtgttatt tgccatcgta atcgcctcat cgaaggtgtc
    15121 gtaacgccag acgcgcaaaa gcggcccgaa gacctcttca tccggcacgc cagtaacacc
    15181 tgtcatttca atgatccccg gcgtcagcaa cgatgttcct gcgcgcagta aacgtggcgc
    15241 aagcagcgtc cgtccgccca tcgcttccag ttcctgccag gcggtaacca cctgctgtgc
    15301 ggcctgctct gatatcaacc cgccaataaa cggctgcggt tcgtcatccc aattgcctgg
    15361 cgttaatcgc tggctgacgg caaccagacg agcaagaaac gcatcgccct gcgccccgct
    15421 tttcagcaat aaacggcggg cgcaggtgca gcgttgcccg gctgtgacaa acgccgactg
    15481 aatggtcaga tggacagcgg catcgatatc cgccgcctca tcgataatta gcggattatt
    15541 accgcccatc tcaagggcga gaattttctc cggctgaccg gagagctggc gatgcaactg
    15601 gtagccggta ttggcgctac cggtaaacag caagccgtcg agatcctcaa gtgcactcag
    15661 cgcctgaccg gtttcgcgcc cgccctgcac caggttcagc acgcccggcg gcaagccagc
    15721 ctgctgccat aaacgcatta ccgcttcgcc actccacggt gtcagttcgc tgggtttaaa
    15781 gataatggtg ttacctgcca gcaatgccgg aacgatatgt ccgttcggta aatgaccggg
    15841 gaaattatac ggcccaaaca ccgccagcac gccgtgtgga cgatgtcgca ggctcgccgc
    15901 gccgtccggc atttcgctac gctgctcacc ggtacgaacg tgatacgcct taattgatat
    15961 cgcgatttta ttgatcatcg ccgtcacttc ggttgccgct tcccagcgcg gcttgccggt
    16021 ttctctggca ataatcgcgg ttaattcggc tttattgctt tccagcaatc cagcaaagcg
    16081 ttcaactctt acctgacgat cgccaaatga gagccgagcc cagcgcggaa acgccgcacg
    16141 ggcagcccga caagcctgcc cgacctgagc agcatcggca tcattgccct gccataacac
    16201 ctcgcccgat accggattac gcttcacacg cgatgcgccc tggcccgtta tccagtcacc
    16261 gttaatccat aaagtcatgc tgttttctcc tctgcgcaca ggcgcaccag acgaacgcga
    16321 tcccctgcgt ggcatttgag ggcatccagt tgtgcggcgg ttaaaatcaa acgctcggtt
    16381 gccggatcgg tacgcaccag caccacgcgg aaatggtgat aattttcatt ggcgaccagg
    16441 caggccggaa aatcgccctg cgcaggctgc ccttctgcca cttccaccag ccgactttta
    16501 cggatggcgc gcacgcggtc gatgtcacac tcaagcgtcg gcccaccgtc gaagatgtcg
    16561 atataattac ggtagcgaaa accttctttc tccagtaccg cacgggcagg cgcggtttgc
    16621 ggatgtacct gaccgatgac gtcctgtgct tcctgggata aaaagtgggt atagatcgga
    16681 tgtttcggca tcagttctgc aataaatgcc ttttgcccgg tgccgcagag aaaatcagcg
    16741 cggctaaaat ccatcgaaaa gaagcgttta ccgaggcttt gccagaacgg tgaatagccg
    16801 tgttcgtcaa tcaccccgcg catttcggcg accactttgt cattaaactt gtcgcgaaaa
    16861 gccgccataa acataaaacg cgatttcgac agcaaatagc cgttgccctc tttgcgccag
    16921 tccgggtcga gaaacagcgt gcacagctcg ctgctgccgg tgtgatcgtt actgagaaac
    16981 agcgtcggca atgcattata gacattcagc tcttttgagg cgtgaaccaa cgtgccgacg
    17041 cgatagttgt accagggatc gttcagccca actgccacct caatggcaca aatccccgcc
    17101 actgtgcctg tctcgctatc ttccagcacg aacacatagc cctgctcact tttgggcagt
    17161 tcgccttgcc aggttttgat tgccctttcg atacgcgccg aaagcgtggc ttcattggcg
    17221 ggaagcgacg tcaggccgcc gcccgttttg ctggcaagct gcatcagcgc cgagacatct
    17281 gagcgctcaa cgggacggat gaccatcatg atgaacctcg gctaacaaag tgttcgcaag
    17341 cagctgcaaa gcgatccagt ccggtcgtca cctcttcttc gctgacattg agcgcaggcg
    17401 caaaacgcac cacgttgcca cccgcaatca gtaccatcac gcctgctttc gccgcttcct
    17461 gagagatctg tttcgcttgc ccggcgtaat cggcattcaa cacgcaacca atcaacaaac
    17521 ctaagccgcg aacttcactg aacaaaccgt agtggtgatt aatggaattt agacgctcaa
    17581 caaaccagtc gtgacgctgt ttaaccccgt taagcatctc tggcgtgttg atgagatcca
    17641 gcactttgcc tgccaccgcc gaggccagcg gattgccgcc ataggtggtg ccgtgagtgc
    17701 caacggtcat cacgctggcg cactcttcgg ttgccaacaa cgcaccaacc gggaaaccgc
    17761 cgcccagcgc tttggcggta gttaacagat caggcgtcac gccgtagtgc atataggcat
    17821 acagttcccc ggtgcgcccg acaccggttt gtacttcatc aaagatcagc aacgcattgt
    17881 ggcggtcaca caattcacgc agaccttgta aaaatgcgtt gctggctggc accacaccgc
    17941 cttccccctg gatgggttcg acaatcaccg cacaggtggc gtcgtcaatc agcgcactgg
    18001 cagagttaat atcgttatat gcagcatgat gaatatccgg cggcagtggc gcaaaatcct
    18061 gtgaataggc tggctgccca cccgcactga cagtaaacag cgtgcgacca tgaaacgcat
    18121 ttttgaacgc cacgatgccg ctcttatggc tgccgtagcg gtcgtgagcg aatttacgcg
    18181 ccagttttag cgccgcttcg ttggcttccg caccggagtt acaaaagaag acgcgatcgg
    18241 caaacgtggc gtcgatcaat ttttttgcca gtcgcagtac cggctcgttg gtgtaaccgt
    18301 tgccggtatg ccagaactta ctcgcctgtt cgttcagcgc ctcacgcagt tccggatgcg
    18361 catggcccag cgcgttcacc gcaatgccac ccgcgaagtc gatatactct ttcccctgct
    18421 gatcccacaa gcgcgaacct tcgccacgta ccggtataaa cggtgccgga gcgtaaacag
    18481 gtatcatcca ttcatcaaag ttttcacgcg taattggctg agacatagcg acctctacag
    18541 taaataattc gttatttata tgttaataat aagtaatgtt tgcgctgtaa atgtagattg
    18601 cagggttcgt gccagccagt gataaaagtg cataaacggc ggaggctaac tggaaatcaa
    18661 gcagttataa ccaaaccata tgcatttaaa gtgcatataa agtgaatacg tttgcgatgt
    18721 gggtgaataa aaagaataaa aaacgcaatg ttatgcagaa gtaaaatata attctggaat
    18781 tgtgatcatt gacgaaattt actggaaatt actgcgccat tctgacgcaa cgcgcaccaa
    18841 aagcgggcat tttttgcgcc atcgttgaca tcattaacaa ccatcgatca aatcacttaa
    18901 caacaggcgg taagcaaagc gaaattctgc taccatccac gcactcttta tctgaataaa
    18961 tggcagcgac tatgaaattt gtctctttta atatcaacgg cctgcgcgcc agacctcacc
    19021 agcttgaagc catcgtcgaa aagcaccaac cggatgtgat tggcctgcag gagacaaaag
    19081 ttcatgacga tatgtttccg ctcgaagagg tggcgaagct cggctacaac gtgttttatc
    19141 acgggcagaa aggccattat ggcgtggcgc tgctgaccaa agagacgccg attgccgtgc
    19201 gtcgcggctt tcccggtgac gacgaagagg cgcaacggcg gattattatg gcggaaatcc
    19261 cctcaccgct gggcaatgtc accgtgatca acggttactt cccgcagggt gaaagccgcg
    19321 accatccgat aaaattccct gcgaaggcgc agttttatca gaatctgcaa aactacctgg
    19381 aaaccgaact caagcgtgaa aatccggtgc tgattatggg cgatatgaat atcagtcctg
    19441 gcgacctgga tattggcatt ggcgaagaga accgtaagcg ctggctgcgt accggaaaat
    19501 gctctttcct tccggaagaa cgcgaatgga tggagagact gatgagctgg gggttggtcg
    19561 ataccttccg ccatgcgaat ccgcaaacag ccgatcgttt ctcatggttt gattaccgct
    19621 caaaaggttt tgacgataac cgtggtctgc gcatcgacct gctgctcgcc agccaaccgc
    19681 tggcagaatg ttgcgtagaa accggcatcg actatgaaat ccgcagcatg gaaaaaccgt
    19741 ccgatcacgc gcctgtgtgg gcgaccttcc gccgctaatt tagctgctct cctggcacaa
    19801 acggagtcag gagaattaac cttgagaaaa atcaacaaac tgtcagtaat gatttgttgc
    19861 ctgccgtcct ttgttatacc gtcacagcgt ttttagttgt ctgaccactt ctctattatc
    19921 aagtttgata taggaaactc cacgatgaac gctgagcgta aatttctttt tgcctgtctt
    19981 atttttgcgc tggtcattta cgctatccac gctttcggtt tattcgagct gctcaccgat
    20041 ttacctcact tacagacact cattcgccag agcggattgt tcggttatag cctctatatt
    20101 ctgttattca tcattgccac cctctttctg ttgccaggaa gcatactggt gatcgctgga
    20161 gggatagttt ttggcccgtt cttagggaca ctactctcat taattgccgc cacgctggcc
    20221 tcctcatgct cattcctgct ggcgcgctgg ctggggcgtg atttactgct gaaatatgtg
    20281 ggccatagcc atacttttaa ggccattgaa aaaggcattg cgcgtaacgg tattaatttt
    20341 cttattctga cccgcttaat cccgttgttt ccttacaata ttcaaaatta cgcttacgga
    20401 ttaaccacaa tcgccttctg gccttatacc cttatttcag cactcacgac tctgcccggt
    20461 attgttattt ataccgtgat ggcaagcgat ctcgccaatg aaggcattac gctgcgcttt
    20521 attttacaac tctgtctggc gggcctggcg ctgtttattc tcgtccagct cgcaaaactc
    20581 tacgcccgac acaaacatgt ggatctgtct gcttctcgcc gcagcccact tactcaccca
    20641 aaaaatgaag gatagaacga tgttgcaaca ttattcagtg tcatggaaaa aaggactgac
    20701 tgcactctgc ttactggctg ttgctgggct tagcggctgc gatcaaaaag agaatgcggc
    20761 ggcaaaagtg gaatacgacg gactttcgaa cagccaaccg ctgcgtgtcg atgccaataa
    20821 ccatacggta accatgctgg tgcaaattaa tggtcgtttc ctcaccgacg acactcgtca
    20881 cggtattgtg tttaaagatg gctccaacgg acataaatcg ctgtttatgg gttatgcgac
    20941 cccgaaagca ttttatgaag ccctgaaaga ggcaggtggt acaccgggcg aaaacatgac
    21001 gatggataat aaagaaacga ctcatgtcac aggcagcaaa ctggaaattt cggtcaactg
    21061 gcaaggggcg gcaaaagcgt attccttcga tgaagtgatt gttgacagta atggcaagaa
    21121 actggacatg cgctttggcg gtaatttaac ggcagcagaa gagaagaaaa cgggctgcct
    21181 ggtgtgtctg gatagctgcc cggtcggcat cgtcagcaat gcaacataca cttatggtgc
    21241 ggttgaaaaa cgcggtgaag ttaaatttaa aggcaatgcc tcggttctcc cggcggataa
    21301 cacgctggca acggttacct ttaaaatcac cgaataaagc caggataaag gatgatgaag
    21361 atgcaatcgc gaaaaatctg gtactaccgt ataaccctca tcatcctgtt gttcgctatg
    21421 ctgctggcat gggcgctgct tcccggcgtc catgagttta tcaatcgcag cgttgcggcg
    21481 tttgccgccg tggaccaaca gggtatagaa cgctttattc agtcttacgg cgcactagcg
    21541 gcagttgtct cgttcttgtt gatgatttta caggccattg ctgcaccgct acctgcgttt
    21601 ttgatcacct ttgccaatgc gtcgctgttt ggcgcgctct ggggcggctt gctgtcgtgg
    21661 accagttcga tggccggcgc ggcgctgtgc ttttttatcg ccagagtgat gggccgcgaa
    21721 gtggtggaaa agttaacggg taaaacggta ctcaatagta tggacggctt ttttacccgc
    21781 tatggtaaac acaccattct ggtatgccga ttattgcctt ttgtcccttt cgatccaatc
    21841 agctatgctg ccggtttgac ttcaatacgt tttcgctcgt tttttatcgc caccgggctt
    21901 ggtcagttac cggcaactat tgtttattcc tgggcgggca gcatgttaac aggcggtact
    21961 ttctggtttg tcaccggact gtttattctg tttgccctga ccgtggtgat ttttatggcg
    22021 aagaaaatat ggcttgagcg ccagaagagg aatgcctgat gggtttaccg ccgcttagca
    22081 aaattccttt cattttacgt ccgcaggcgt ggctgcatcg tcgccattac ggcgaggtgc
    22141 taagccccat tcgctggtgg gggcggatcc cgtttatctt ttatctggtg tcgatgtttg
    22201 tcggctggct ggagcgcaaa cgctcaccgc tcgatccggt agtgcgatcg cttgtcagcg
    22261 cgcgcattgc gcaaatgtgc ctgtgtgagt tttgcgtgga tatcaccagt atgaaagtcg
    22321 ccgagcgtac cggcagcacc gataaactgc tggcagtggc tgactggcgg caaagcccgc
    22381 tctttagcga tgaagaacgg ctggcgctgg agtacgccga agccgcaagc gtcacaccgc
    22441 caacggtcga tgatgccctg cgtacccgac tggctaccca ttttgacgct caggcactca
    22501 ccgaactgac ggcattgatc ggcctgcaaa atctgtcagc ccgttttaat tctgccatgg
    22561 acattcccgc tcaggggctg tgccgtattc ctgacaaacg ttcttaagga gagatgatgc
    22621 gccattgtgt atggttgctg ggattgttat cgctgttttc tttggcaaca catgccagtg
    22681 actggcagga aattaaaaat gaggccaaag ggcaaaccgt ctggtttaac gcctggggcg
    22741 gcgataccgc aattaaccgc tatctcgact gggttagcgg cgagatgaaa acccattacg
    22801 ctataaacct gaagattgtt cgtctcgcgg atgccgcaga cgcggtgaag cgcattcaga
    22861 ccgaagctgc tgccggacgc aaaacaggcg gttcggtgga tctgctctgg gtgaacggcg
    22921 aaaacttccg caccttaaaa gaggccaatt tattacaaac gggctgggcg gagactctgc
    22981 ccaactggcg ctatgtcgac acacagcttc cggtgcggga agatttttca gtgcctacag
    23041 aaggggctga atcgccctgg ggcggcgcac aactgacgtt tatcgcccgc cgcgatgtta
    23101 cgccacagcc accacaaacg ccgcaagcct tactggagtt tgctaaagcc aatcccggca
    23161 cggttaccta tccgcgccca ccggacttta ctggcaccgc atttcttgaa cagttactga
    23221 ttatgctgac gccagatccc gcagcattaa aagaagcacc ggacgatgcg actttcgccc
    23281 gtgtcactac gcccttgtgg caatatcttg atgcactgca tccgtatttg tggcgcgaag
    23341 gaaaagattt cccgccttca cccgcgcgga tggatgcgct gctgaaagct aacacattgc
    23401 gcctgtcgct gacctttaac cctgcacatg cgcagcaaaa aatcgccagc ggcgatttgc
    23461 ctgcaagcag ttacagtttt ggttttcgcg aggggatgat tggcaacgtc catttcgtca
    23521 ccattcctgc caacgcgaat gccagtgctg cggcgaaggt agttgccaat ttcttgctct
    23581 cacccgatgc gcaactgcgt aaagcagatc ccgctgtctg gggcgatcct tctgttctcg
    23641 atccgcaaaa actgcctgac gggcagcgcg aatccttgca atcaagaatg ccgcaagatc
    23701 tgccgccggt actggctgaa ccgcacgcag gttgggtaaa tgcgctggaa caagaatggc
    23761 tacaccgtta cggtacgcat taatcttttt gctgtgggcg atggtggcgg tgatttatgc
    23821 accgctgatc ccggcaactc tcacgctgat atcgcctgct ttatcgttga cacactggca
    23881 ggcgttattt gccgatccac agttaccgca ggcattactg gcaacgctgg tgtcgacaac
    23941 catcgcggcg gtcggggcgt tgttgattgc cttgctggtg attgtggcgc tgtggcctgg
    24001 gccgaaatgg cagcgtatgt gcgcccgtct gccgtggctg ctcgccattc cccatgtggc
    24061 ttttgcctcc agcgcccttc tgctctttgc tgacggaggg ctgctttatg actatttccc
    24121 gtatttcact ccgccaatgg acaaattggg tattgggctg ggcctcaccc tggcggtgaa
    24181 agaaagcgca tttctgctgt ggatcttagc ggcagtattg agcgaaaaac ggctgttgca
    24241 gcaagttatt gtgctggatt cactgggcta cagccgctgg caatgtttga agtggctgct
    24301 tttgccctct gtcgcgcctg cgctggcaat ggcgatgctg gcgattgtag cctggtcgct
    24361 gtcggtcgtg gatgtggcga ttacccttgg gccaggtaat cccccgacgc tggcagtaat
    24421 tagctggcag tggttaactc agggcgacgc cgatcaacaa acgaaaggcg cactcgccag
    24481 cctgctgctg atgctgttac tcgccgccta cgttttgctg ggctatctgc tatggcgtag
    24541 ctggcggcgt actattcccc gcgtagatgg cgttcgtaag cctgccacgc ctttattgcc
    24601 aggcattacg ctggcgagtt ttttaccctt aaccggtgtg ctgtgtgtgg ttctgctggc
    24661 gatcctcgcg gatcagtcga cgatcaatag tgaagcgctc atcaacagcc tgacaatggg
    24721 gctggtggcg acattcatcg ctttgctcct gttactgctg tggctggaat gggggccaca
    24781 gcgtcgccag ttgtggctat ggttgcccat tttattaccc gctctgccac tggtggcggg
    24841 ccagtacacg ctggcgctat ggctgaacct ggatggaagc tggacggcgg tggtctgggg
    24901 gcatctgctg tgggtaatgc cgtggatgct gtttatcctg caacccgcct ggcagcgcat
    24961 tgattcacgg ttaattttga ttgcgcaaac actgggctgg tcgcgggcca aaatcttctt
    25021 ttacgtaaaa tgcccactca tgttgcgccc tgcgctgatt gccttcgcgg tgggattttc
    25081 agtcagtatt gcgcagtata tgccgacgct gtggctgggc gcggggcgtt ttccgacgct
    25141 caccactgaa gcggtggcat taagcagcgg cggcagcaac ggtattctcg ccgcccaggc
    25201 tttatggcaa ctgctgttac cgcttattat ttttgccctg accgcgttag tcgcaaaatg
    25261 ggtaggttat gtcagacaag gactccgcta atgctctgcg tgaaaaatgt ttcgctacgt
    25321 ttaccagaaa gccgcttgct gacaaacgtt aactttacgg tggataaagg tgacattgtc
    25381 acgttaatgg ggccgtctgg ctgtggaaaa tctacactgt tttcatggat gattggtgcg
    25441 ctggccggac agttttcttg tacaggtgag ctatggctca atgagcaacg gattgacatg
    25501 ctacccaccg cagagcgtca gattggcatt cttttccagg atgcactgtt atttgaccag
    25561 ttcagcgtcg ggcaaaattt actgctggct ctgccagcgg cactcaaagg tgttgcaagg
    25621 cgcgatgcgg taaatgatgc gctggagcgt gcggggcttg gcggtatgtt ccatcaggat
    25681 cctgccactt tgtctggcgg tcagcgagcg cgcgttgctc tgctgcgcgc ccttctcgct
    25741 cagccaaaag cgttgctact ggatgagcca ttcagccgtc ttgatgtggc tctgcgcgat
    25801 aattttcgcc agtgggtgtt cagcgaagtt cacgccctgg cgatccccgt cgttcaggta
    25861 acgcacgatc tccaggatgt tcctgctgat agttctgttc tggatatggc gcagtggtca
    25921 gaaaattaca acaaactgcg ataacgcaaa gtttttctca atgcgtcagt tcagaatggc
    25981 gcactcaaaa ctacaatgtc gggattttcg atgaaacgtg tttctcaaat gaccgcgctg
    26041 gcaatggctt tagggctggc ttgcgcttct tcgtgggccg ctgaactggc gaagcctctt
    26101 acacttgacc agcttcaaca acaaaatggc aaagcgatag atactcgccc cagcgcgttt
    26161 tataacggct ggccacaaac cttaaatggc ccttctggtc atgaacctgc cgccttaaac
    26221 ctctctgcca gctggctcga caaaatgagc accgaacagc tcaacgcgtg gatcaagcaa
    26281 cataacctga aagccgatgc tccggtggcg ctgtacggta atgacaaaga tgtcgacgcc
    26341 gtcaaaacgc gactgcaaaa agcaggtttt acgcatatct ccattctgag tgacgcgcta
    26401 agcgaacctt cccgtctgca aaaactgccg cattttgagc agctggttta tccgcaatgg
    26461 ctgcacgacc tgcaacaagg taaagaggtt acggcgaaac ctgccggtga ctggaaagtc
    26521 attgaagcgg cctggggcgc tcctaagctt taccttatca gccatattcc cggcgctgac
    26581 tacatcgata ccaacgaagt ggaaagcgaa ccgctgtgga acaaagtttc tgatgaacaa
    26641 ctgaaagcga tgctggcaaa acacggcatt cgccatgaca ccacggtcat tctgtacggg
    26701 cgtgacgtat acgctgcagc gcgtgtggca caaattatgc tctacgctgg cgtgaaagat
    26761 gtccgcctgc tggacggcgg ctggcaaacc tggtccgacg cgggactgcc cgttgagcgc
    26821 ggaacgccac cgaaagtgaa aacggaaccg gatttcggcg tgaagatccc ggcacaaccg
    26881 caactgatgc ttgatatgga acaggcgcgt ggactgctgc atcgccagga cgcctcgctg
    26941 gtgagtattc gttcgtggcc ggagtttatc ggtacgacca gtggttacag ctatattaaa
    27001 ccaaaaggtg aaatagccgg agcacgttgg ggacacgctg gtagcgactc gacgcatatg
    27061 gaagatttcc ataacccgga tggcaccatg cgcagcgccg atgatattac ggctatgtgg
    27121 aaagcatgga atatcagacc agatcagcaa gtttcattct actgcggcac cggctggcgc
    27181 acgtccgaaa cctttatgta cgcacgagca atgggctgga ataacgtctc cgtttacgac
    27241 ggcggctggt acgaatggag cagcgatcca aaaaatccgg tagcaaccgg tgaacgcggc
    27301 ccggacagca gcaaataaca ttgcaattac tgacgctgga gcgacttcag cgtcagatac
    27361 ccactccaca cccgcgtaaa ggtcgtcatc cagcacaacg caccaaatac ccacgcaaac
    27421 cacggaaaac aggccggaaa gaggcaactc agaacaaaca gcaaaatcgt ctcgctgcct
    27481 tcggttaacc cgcccagata ataaaacgat ttatgcgcat aaccaggatt atcaatctga
    27541 tgtttcgccg ccagcgcagc aaaagcgaga aaactgctgc ccgtgccgat aaacgcaaac
    27601 agcagccagc cgcctgccag cgcattttgc tccggtgcag caagaataaa accaaacggc
    27661 accagcgcgt aaaagagaaa atcgagagaa atatcgagaa agccgcccgc gtcggtaagc
    27721 cctctgcgcc gcgccagcgc accgtccaga ccatcaagca gcctgttcaa caaaatggcg
    27781 actagcgccg ccagatacca gcccagcgcc agaaaaggca gtgccagcac gccgatggca
    27841 aatcccacta atgttaaacc atctggcgta atgcccggtt tatcaagaac ccgcacgcac
    27901 tgatgcaaca acggtttaat ccggggatga agatggcggt ctagcacagg cactccttaa
    27961 atataaagcc tttctgattg agcaacagtg cggatattat ggcatttttc gcttatctgc
    28021 ccgtgtgtaa tttatgaaaa tgattgaagt tgttgccgcc atcatcgaac gtgatggcaa
    28081 aattttactc gcgcaacgcc ctgcccatag cgatcaggcg ggattatggg agtttgccgg
    28141 tggtaaagtc gagccggatg aaagccagcg gcaggcgctg gtgcgtgagt tacgcgaaga
    28201 actgggcatc gaagcagctg tgagtgaata tgttgccagc catcagcgag aagtttcggg
    28261 gcggattatc catcttcatg cctggcacgt acccgacttc cacgggacgt tacaggcaca
    28321 tgaacatcag gcgctggtct ggtgctcacc tgaagaggcg ctgcaatatc cgctggcccc
    28381 tgctgacatt ccactattag aggcgtttat ggctttacgc gccgccagac cagcggatta
    28441 gtgctaaggg ttttgtcatc acgctggcat tgcagcagta ttccttcggc tttaattacc
    28501 gccccttcag aataattttg atcctgataa acgcagcact gagtacaggg ctgcgctgac
    28561 tgcccgcctg aactgaacac ttctggcggt acgtttacct ccacgtccgg atgataatgc
    28621 gggttagcca gtgcaattaa tggaaatgct aatactacgg cgaacaatgc tcgactcaca
    28681 gggaactcct taacgttatt gtctctgcta ctaataacgg tagccgggcg gcataacttt
    28741 agcgtctgag ttatcgcatt tggttatgag attactctcg ttattaattt gctttcctgg
    28801 gtcatttttt tcttgcttac cgtcacattc ttgatggtat agtcgaaaac tgcaaaagca
    28861 catgacataa acaacataag cacaatcgta ttaatatata agggttttat atctatggat
    28921 cagacatatt ctctggagtc attcctcaac catgtccaaa agcgcgaccc gaatcaaacc
    28981 gagttcgcgc aagccgttcg tgaagtaatg accacactct ggccttttct tgaacaaaat
    29041 ccaaaatatc gccagatgtc attactggag cgtctggttg aaccggagcg cgtgatccag
    29101 tttcgcgtgg tatgggttga tgatcgcaac caggtacagg tcaaccgtgc atggcgtgtg
    29161 cagttcagct ctgccatcgg cccgtacaaa ggcggtatgc gcttccatcc gtcagttaac
    29221 ctttccattc tcaaattcct cggcttcgaa caaaccttca aaaatgccct gactactctg
    29281 ccgatgggcg gtggtaaagg cggcagcgat ttcgatccga aaggaaaaag cgaaggtgaa
    29341 gtgatgcgtt tttgccaggc gctgatgact gaactgtatc gccacctggg cgcggatacc
    29401 gacgttccgg caggtgatat cggcgttggt ggtcgtgaag tcggctttat ggcggggatg
    29461 atgaaaaagc tctccaacaa taccgcctgc gtcttcaccg gtaagggcct ttcatttggc
    29521 ggcagtctta ttcgcccgga agctaccggc tacggtctgg tttatttcac agaagcaatg
    29581 ctaaaacgcc acggtatggg ttttgaagga atgcgcgttt ccgtttctgg ctccggcaac
    29641 gtcgcccaat acgctatcga aaaagcgatg gaatttggtg ctcgtgtgat cactgcgtca
    29701 gactccagtg gcactgtagt tgatgaaagc ggattcacga aagagaaact ggcacgtctt
    29761 atcgaaatca aagccagccg cgatggtcga gtggcagatt acgccaaaga atttggtctg
    29821 gtctatctcg aaggccaaca gccgtggtct gtaccggttg atatcgccct gccttgcgcc
    29881 acccagaacg aactggatgt tgacgccgcg catcagctta tcgccaatgg cgttaaagcc
    29941 gtcgccgaag gagcaaatat gccgaccacc atcgaagcga ctgaactgtt ccagcaggca
    30001 ggcgtactgt ttgcaccggg taaagcggct aatgctggcg gtgtagcaac atcgggcctg
    30061 gaaatggcgc aaaacgctgc gcgcctgggc tggaaagccg agaaagttga cgcacgtttg
    30121 catcacatca tgctggatat ccaccatgcc tgtgttgagc atggtggtga aggtgatcaa
    30181 accaactacg tgcagggcgc gaacattgcc ggttttgtga aggttgcgga tgcgatgtta
    30241 agccagggcg tgatttaaga caattgtgcc ggatacagcg caaacgcctt atccggccat
    30301 aaaaatcttc agtatcagat ggttgaaaga acctttatat tatcactcca ttgcccgcct
    30361 cttctgatgg cgggcttttt ttcggcgctc tcttgcgtgg cgaatccttt ttcttccctt
    30421 ctccaccgcc gggagccatt attccccgaa actgccttac cgacgtgcgc tttgcctgat
    30481 caatcaactg gtacaatgtc cccaccagcg gctgcataaa gtcctggtag cgacactgct
    30541 tttcgctgat ttgcgtcagc accgattccc agtgcgcggt catgtccggt cgcgtcgcca
    30601 tttctggcag cgaatggaat agcgcttttc cggcgtcggt ggagtggata tagcgccctt
    30661 ttttggtcag gaaaccacgc ttgaacaaca gttcaataat cccggcacgg gttgcttctg
    30721 tccccagacc atcggtcgca cgaaggatct ttttcagatc tttgtcctgc acaaagcgtg
    30781 cgatcccggt catcgccgaa agcagtgttg catcggtaaa atggcgcggc ggctgggttt
    30841 gccgctctac cacttcacct ttttcgcaca acaattcatc gcctttcgcc accacaggca
    30901 gcggcatgcc gtcgttttct tcatcgcgct ctttgctgcc taacagcgtg cgccagcctg
    30961 cttcagcaag aaaacgggct ttagcgacaa atttgccttt ggcaatgtcc agttcgataa
    31021 cacacttgcg gaacaccgca tccgggcaga actgcatcaa gtactgacgg gcaatcaggt
    31081 tatagacctt cgcttcgttc tccgtcaggt tgatcgcaga actccgtgcg gtcggaatga
    31141 tggcgtggtg cgcatcgacc tttttgtcat cccaacagcg gttgcgtata tctggatcta
    31201 ccactggctg cggcaacaga tccggtgcat gaacgctgat agcattcatc accgcgtggc
    31261 gtccggcaaa atgttcttct ggcaaatagc ggcaatcgga acgcggataa gtgattagct
    31321 tgtgcgtttc gtacagcttc tggcagatat caagcacgtt ctgcgcgctc agaccaaaac
    31381 gtttagccgc ttcaatctgc aacgccgaaa gcgaaaaagg aagcggcgcg gattctgatt
    31441 cccgtttatc gttatagctg gtgacaatag ctggttgacc actaatgcgg ttaaccacat
    31501 gctccgccag tggacgatgt aacaagcgcc cttcttcatc ctggtacggt tcacacgctt
    31561 cgctcggttg ccagatagcg gtaaaccgct catcggcagg tgtcacgata tgtgctttga
    31621 cttcaaagaa atctttcgcc acgaagtttt caatctcttc gtcgcggcgc accaccagtc
    31681 cgagtacggg cgtctgcacg cgtcccacgg aaagtacgcc ctgataaccg gcattgcgac
    31741 cgagaatggt gtaagcgcgg gtcatattga tgccgtacag ccagtcagct cgggctcgcg
    31801 ccagtgcaga aacgcacagc ggtacaaact cgctattgga gcgaagacga tcgatcgccc
    31861 gctcaaccgc ctgcgggttc aggtcgttta tcaaacaacg ctgtacctgc tggcgctttt
    31921 ccggtgccag ttgcaggtag tccagcactt catccaccag cagttgccct tcgcgatccg
    31981 ggtctccggc gtgaacgatt tcgctggctt catgcaggaa gcgtttgatg acattaagtt
    32041 gtttagtcac ggagggtcgg ggctgtaatt gccacttttc cgggacaatt ggcaaatccg
    32101 caagattcca gcgcgcatag cggctgtcgt aggcgtctgg ctgcgcctgc tcaagcaggt
    32161 gaccgataca ccaggtcacc acctgaccat taccgcactc gataaagcca tcgcctttcc
    32221 ggtgcggttt aggcaggaca tcagcaatgg cgcgcgccag actcggtttt tcggcaataa
    32281 acaaccgcat tgaattaacg gatctcaacc atggcacgac cgccgcgcgc tggcaccagt
    32341 tcgccaatcg ccgtcagttc aatgccaaac tcggcggctg tagctttgac ctcattttct
    32401 gcttccggca tgaccgccag cagcaaaccg ccagaagttt gcggatcgca cagcagatcg
    32461 cgcacttcac gcggcatttc acccatcaga tgaccgtagc tggcaaagtt acgttcggtg
    32521 ccgccaggca ctgcgcccaa cttaatgtac tcttcaaccc caggcaattt cgggatcgcg
    32581 tcatagtcga cgcgcgcctg cacacctgcg ccctgacaca tttcgcttaa atgccccagc
    32641 aaaccaaaac ccgtaacgtc tgtcatcgct tttacgcctt cgatgttggc aaaggacgcg
    32701 cctgcgatgt tcatccggca catcacttcc gtcgccaatc cctgatgttc tggtttaagc
    32761 agtgattttt tctcagccgt ggtaagaacg ccaatcccca gcggtttcgt caggaacagt
    32821 ttgcatccgg cttgtgcggt actgtttttc ttcacccgct cggtcggtac gatccccgtt
    32881 accgccagac caaaaatcgg ctccggcgca tcgatggagt gaccgccagc cagcgcaata
    32941 cccgcctgac ggcatgcata gcgtccacct tcggtcactt cgcgggcaat ttccggggaa
    33001 agtttgttaa tcggccagcc gaggatcgca atcgccataa tcggtttgcc gcccattgcg
    33061 aagatatcgc tgatggcgtt agtcgccgca atgcggccaa aatcgaaagg attatcaacg
    33121 atcggcataa agaagtcggt ggtactgata acgctggtgc cattgcccag atcgtacacc
    33181 gccgcatcgt cgcgggtttc attacccaca agcaaattcg gatcaacaaa cttcgcctgc
    33241 tcactgtgca ggatggtttc caacactttt ggggaaattt tacagccgca accagcgccg
    33301 tggctgtatt gggtcaaacg aatcgagttc tcgctcatgg acatctcctg tcaatgcaat
    33361 ccgggtatgg taaccctcat tccatgaagt gataagtgag agtgtctgaa ttcctgcgcc
    33421 tttgctcaca atccagacag tttcgcgaca attatcagaa ataagtcaca aacggcgtcg
    33481 ggtccgggac gtttatcgac gtagatgctt tcaactgcgg cgtaccgagg tagagaaaac
    33541 cgacaatttt atcctgctca cggcaaccga atgcttcacg cactaccgga ctttcagtta
    33601 atgcaccact gcgccagatg ccgccaaacc cctgggcaac tgctgccatt tgcatcgcca
    33661 tgaccgcgca tcccgcagac atttcctgtt cccagcgcgg gactttatga ttttcttcgc
    33721 atttcgccac caccgttatg atgagcggtg cgcggaacgg cgcattacgc gctttgtcga
    33781 tggctttgtt atcactaccg gcagcaatcg ccccctgctc cagtacagcg ctgaaacgct
    33841 cgcgcccttc cccttcaatt acaaagaaat gccacggttg catggactta tggtccggcg
    33901 cacgcatacc cgcacgcagg atgttttgca gttgttcacc cgttggcgcg ggttcagcca
    33961 ggcgggaggc gctacggcga ttgatcaata gttcgagtgc atccatttga ttaactcctg
    34021 tcatgatatt tattcacaaa attaacacga gagtggattt tgttacagcc cagtccgcaa
    34081 ttcctgctga caagtgccgg ttgggtcatt acgataacca catctattgc gcctgagaca
    34141 ggtgtgacct taagttggga gaatacatgc gaaccctttg gcgatttatt gccggatttt
    34201 ttaaatggac gtggcgtctg ctgaatttcg tccgtgaaat ggtacttaac ctgttcttta
    34261 tttttctcgt gctggttggt gtggggatct ggatgcaggt cagtggtggt gattcgaaag
    34321 aaacggccag tcgtggcgca ctgctgctgg acatttctgg tgtgatcgtc gataaacccg
    34381 acagttctca gcggtttagt aaattaagcc gccagctgct tggtgccagt tccgatcgtc
    34441 tgcaggaaaa ctcactgttt gatatcgtca acaccattcg ccaggcgaag gacgaccgca
    34501 atatcaccgg tattgtgatg gatctgaaaa acttcgcagg cggcgaccag ccgtctatgc
    34561 agtacatcgg caaagctctg aaagagtttc gtgacagcgg gaaaccggtt tatgccgttg
    34621 gcgagaacta cagccagggg caatattatc tcgccagttt cgccaataaa atttggctgt
    34681 caccgcaagg cgtggtggat ctgcacggct ttgccaccaa cggtctgtac tacaaatcgt
    34741 tgctggataa gctgaaagtt tccacccatg tgttccgcgt gggtacgtat aaatctgccg
    34801 ttgaaccgtt tattcgtgat gatatgtcgc cggcagcccg cgaagctgac agccgctgga
    34861 ttggtgagct gtggcaaaac tatctgaata ctgttgccgc taaccggcag atccctgctc
    34921 agcaggtatt ccctggcgcg caagggttgc ttgagggttt aaccaaaacc ggtggcgata
    34981 ccgcgaaata tgcgctggaa aacaagctgg tcgatgcact ggcatcgagt gccgaaatcg
    35041 aaaaaactct gaccaaagag ttcggctgga gcaagactga taaaaattat cgcgccatca
    35101 gttattacga ttacgcattg aaaacgccgg cagataccgg tgacagcatc ggagtcgtct
    35161 tcgctaatgg cgcaattatg gatggcgagg aaactcaggg gaatgttggc ggtgatacca
    35221 ctgcggcaca aatccgcgac gctcgccttg acccgaaagt gaaagcgatt gtcctgcgtg
    35281 ttaatagccc aggcggcagc gttaccgcgt ctgaagtgat tcgcgctgaa ctggcagcag
    35341 cccgggcagc gggtaagcct gtggttgtat cgatgggcgg catggcggca tctggtggtt
    35401 actggatttc cacgccagct aattacattg tggctaaccc cagcaccctg accggttcta
    35461 tcggtatctt cggcgtgatc accaccgtag aaaatagtct ggattcgatt ggtgttcata
    35521 ctgatggtgt ctcaacttca ccgctggcgg atgtttctat caccagggca ctgccgccgg
    35581 aagcgcagca gatgatgcag ttaagcattg agaatggcta taaacgcttt atcacgctgg
    35641 ttgctgatgc gcgtcattca acgccggagc agattgataa aatcgcccag ggccacgtct
    35701 ggaccggtca ggatgcaaaa gctaacgggc tggtcgatag tctcggggat ttcgatgatg
    35761 cggtcgccaa agccgcagag ctggcaaaag tgaaacagtg gcatctggaa tactacgttg
    35821 atgaaccgac cttcttcgac aaagtgatgg acaacatgtc tggttctgtc cgggcaatgt
    35881 tgccagatgc gttccaggcc atgttacctg caccgctggc ctcggtagcc tctaccgtta
    35941 aaagtgaaag cgacaagctg gccgcgttta acgacccaca aaaccgttat gcgttttgcc
    36001 tgacctgcgc caacgtgcgt taagtcatgt actaagtggc cgacagatcg tcggccacat
    36061 tactttttac gtcgacgaat cctcttcccg ctgtctcgcc ccatatttcc ttatccgcat
    36121 agtatcaggt gcgctccccc tgcctcacgt atatactttt gctctttcga tatcattcat
    36181 atcaatatca tgcaaaagaa atcaatttac gtcgcctaca cgggcgggac catcgggatg
    36241 cagcgttccg agcagggtta tattccggtg tcaggtcatc tacagcgcca actggcgctg
    36301 atgccggaat tccatcgccc ggagatgcca gatttcacca ttcatgaata tacgccattg
    36361 atggattctt ctgatatgac gccagaagac tggcagcata ttgctgaaga tattaaagcg
    36421 cattatgacg actatgatgg ttttgtcatt ctgcacggca ccgacacgat ggcgtatacc
    36481 gcctctgcac tgtcgttcat gctcgagaat ctcggtaaac cggttattgt gacagggtca
    36541 caaatcccgc tagctgagtt acgctctgac ggacaaatta atctgctgaa tgcgttgtac
    36601 gttgcggcga attatcctat caacgaagta actctctttt ttaataatcg actttatcgt
    36661 ggcaaccgta ccaccaaagc ccatgccgat ggttttgatg cgtttgcctc tccaaacctt
    36721 cctccgttac tggaagcagg tatccatatt cgtcgtttga atacgccacc cgccccgcac
    36781 ggtgaagggg aattgatcgt tcatccaatc accccacaac cgattggcgt agtgacgatt
    36841 tatccaggga tttctgctga cgtcgtgcgc aattttctgc gccaaccggt gaaagcattg
    36901 attctgcgct catatggcgt gggtaatgcg ccacaaaaca aagccttcct gcaagaatta
    36961 caagaagcca gcgatcgcgg tattgtggta gtcaacctga cacaatgtat gtccggtaaa
    37021 gtgaatatgg gtggttatgc caccggtaac gccctcgccc atgccggcgt tattggcggt
    37081 gcagatatga ctgtagaagc cacactaacc aaactgcatt acctgcttag ccaggaactg
    37141 gatactgaaa ccattcgcaa ggccatgagc caaaacctgc gcggcgaact gacgccggat
    37201 gattaaggag actgcaatgc cccctcgcgc cctgttactg gtcgatttac aaaatgattt
    37261 ctgtgctggt ggcgcgctcg ccgtgccgga aggtgacagt acggtggatg tcgctaaccg
    37321 cctgattgac tggtgccagt cgcgcggtga agcggttatc gccagtcagg actggcaccc
    37381 ggcgaatcac ggcagttttg ccagtcagca cggtgtagag ccttatacgc caggccaact
    37441 cgacggtttg ccacaaacct tctggccaga tcactgtgtg cagaacagtg aaggcgcaca
    37501 attacatccg ttactgaacc aaaaagcgat cgcagcggtg ttccataaag gcgaaaatcc
    37561 tttagttgac agttacagtg ccttttttga taacggccgt cggcagaaaa ctgcgctcga
    37621 tgactggttg cgcgctcatg taatcaatga attgatcgtt atgggtctgg ctactgacta
    37681 ttgcgtgaag tttaccgtgc tggacgcgtt acagttaggc tataaggtga acgtgattac
    37741 cgatggttgt cgtggcgtaa atatccagcc acaggacagt gcgcacgcgt ttatggaaat
    37801 gtcagccgct ggggcaacgc tatatacgct ggcagactgg gaagaaacgc aggagtaatt
    37861 ttacgctggc ctacaattct gtactggcat tgtaggccag ataaaacaca tcagtgatac
    37921 atctggtaat tgacgccatc aacgaaagat ttaattcacc tcagaaatct cttccagcga
    37981 caccttccgc gtttcgatgc caaaaatgga gagaaccagc gcacagagca ctaacatgac
    38041 accaagcacc ataaacaccg tgatcgaccc ataatgtgtt aataatgccg caacgccata
    38101 gggcgtgaag actgcgacga tccgtccgac ggcattaacg aaacccgaac cgcgcaagcg
    38161 taaatgcgtt ggccaaagtt ccgggatata aaccgccgac gcgaagcaca catacatgta
    38221 taaaaagaag atcatcacca ggccatagat taaaatcgcc cactctgtag tctgaattga
    38281 atagatatag cctaacacag caataataat aagtaaggca gagccaaata atcgacgagg
    38341 aaaatgatca ataattaatg ccgcaataaa tatccctacc ggagcgccaa tcataataac
    38401 agcggtcatt aatattgatt tatcaacatc aatgccggag ttaacaaata tggtcggtat
    38461 ccatacggtg atggtataaa gcgaaatgtt cattgcaatt aaaacagtaa tcgcgactaa
    38521 tgtacgtcgt aacatttccc ctttaaacag gagccagaag gtacccttga ttaccttaac
    38581 cttgctgttg ctctggttca aagtaagcgg gggtaaacga acactcttct ctctttcaat
    38641 ttgctgctct acttcacgaa gttggctttc tgcacctgcg atttgtcctt tccccgccaa
    38701 ccatcgaggc gactcaataa agtatttacc tgagagaaac caggctaaca gtatgccaat
    38761 accacccagc agaaacatta tccgccaact aaaaaaagcg ataaccacca cgcctatcgc
    38821 cgcagacaac atgggcgacc agttaccgac aaatgagagc cgcgcggacc attttccacg
    38881 caccgtcgcg gggataaact ccgtaaatga ggcatagcca accataatca gcgcccccat
    38941 tcctgttccc atcaggaagc gaaagaagat gagccagtac atatcaggga caaaagcggc
    39001 ccctgttgcc gcaataccga cgatgagaag atttatgcga aacgccctgc gccgcccaaa
    39061 gtagtcacca ataaacccac cggtaagaga gccgatgaaa taaccaaaca ttaatgccga
    39121 ggtaaaggcg gcattgagaa aattatttga ccatccattg cttaccagct ttgctaaaac
    39181 aacattgcct gaataactca aaaaacccgt taataacaga ctaaagctta taataccaaa
    39241 tatacgataa tgaaaccggg ccaaaggcaa gcggtccagt cttgcgccaa tttgatcata
    39301 ttgttccatt aggtgcctcg gatttgctaa aaaggtagca attgcggcaa attcacttgc
    39361 cgcatcttta tcatcatttt atttccaggc gcaggaacaa ataatattga caacgtgtgc
    39421 ttaaattacc acaccagctg gatattattg tctttgcaaa atgctatcca ctctgcaccc
    39481 ggtgatttat cagttattat gtaattaata tgactaaagt cagctaactg gacaaaagct
    39541 ttgcgatcaa acttagagtg atcaaccaat aacgcaactt ctgtcgcctg acggatcatt
    39601 gtctttttga tttcagcttc cgcttcgtta gagtccagcg cgccgctgtt aatatcaaga
    39661 cctttacaac tcattaccat gatatcgaca tggtagcggc tgatgatctc tttagtaatt
    39721 cttccttgca gggaaagtgt atttttgttt agttccccac ccgttgaaac gactttaatt
    39781 tctgactgag ccagaacatg aatcgcttcc gccgagttgg ttagcaacgt caggtcacta
    39841 cggtcctgta acaatttgag caattccatt acggtactac tggaatcggc tgccatggtg
    39901 gttttattgt cgataaaggg taatgccttg cgtgcaataa gctgcttctc ttcataaaac
    39961 gatgaagcgc gcttataaaa atggatattc tccgtcaaca tcgctgtatt taaaacagca
    40021 ccaccatagg ttctggtcaa aaagccttca tcttccagct tctcaagatc gcggcgaatg
    40081 gtttcttcgg ttacctgaaa aatcccactc aaatttgaga ctgtcacctt tttatcgttg
    40141 gcaaccattt gcttaattgc ctgaatcctg tcttttgccg ccacgattac acccctgtat
    40201 ctttttacat cacattagcg cgattatcgc ataattgatg tttactttca aaataacctg
    40261 tttgaatcac agattttcat cacagttttc acagaaacag aggtgaatcg tgttgagtat
    40321 ttaacgctcc agggcctctg ccatttccct catcaatgtt gcgtctgcat ccgataagtt
    40381 gatattcaat gccgcgacat tttcgcgtac ctgttccggt gcagtagccc cactaagaat
    40441 ggagattaaa tcactctgtt ttaatatcca cgccagtgcc agagtgggaa ttgtgcactg
    40501 ataacgagca cagagtggct gccactgttc aagcatatca atcactttca gcatgttttc
    40561 acgctggaac cagactttat ttgcccgagc gccgcccgga acgtaatcac gagtgatggt
    40621 accggtcaac aatccctgct ctagcgggga ataaacctgt accacaatgc cattatcacg
    40681 acatagcggc agcagttcgc tttccattgc ccggtcgagg atactgtatt tcgcctgaat
    40741 aatatccagt tcaccatatt gtagatactc gcggatatgg tcagcatcga cgttagcagc
    40801 gcctatagcg cgaattttcc cttcggcctt taactcattg agcactgcga cagtttcagc
    40861 gatcggcgta aaaaatggcg gcaccgactg ccagtgcgtc atgtagatat cgatgtaatc
    40921 aatacccaga cgttgcaagc tggcttctac ctcttcgcgg atagattcag gggaaaggtt
    40981 tttatacaac tgccgatcgc caactttgtt gaataaactc ccttttcgtt cccagacaat
    41041 gccgcatttg gtttctacta caacctgttc acggggcagt ttttttaacg cctgaccgac
    41101 gataacttca ctattgccaa agttatatcc tggcgcagta tcaatcagat taatgccaca
    41161 acgatgggct tcaagaatcg tatcaataca tatttgccga tcgagatcgc cattccatgc
    41221 aggaccgccg ccaatggccc atgtccccaa ccccattcgc gaaagcgtaa tatccgttgt
    41281 gcctaaaggt atctttttca tttgccttca ttatccttcg tattcttcca gcaattgttc
    41341 gaccagtttt ctgtttttta caccggtggt ggcaccgacg ctcaaaacag agatagccgc
    41401 cgttgcattg gcaaagcgtg cgcattcacg cagatttttg ccttctaaca gagccgctat
    41461 aaagccagaa gcaaagttat cgcctgcgcc aatagtgtcg atggcggtta ttcctgcgac
    41521 cgccggcacc ttcatcgtca tgtcaccacg cttgataaag cagccgtctt tacccgtttt
    41581 aatcaccacc gtttttacgc cgcacgcaag aaagcagtca gcaatttcat ccagtgtctc
    41641 tttcccggtg agtaattttg cctcggcaaa attaggaaac agataatcga cataactcaa
    41701 tgcttcgcaa atatcatcca gcgtttcatt caaccgcggt ttgatcatat cggcacagat
    41761 aatcatctgc cgggctttag cttgcgtaaa aatttctgtt agcgctttac catccaatag
    41821 aggactgttg aaaatactgg ccagagataa taatttcgcc tgagaaaacc gcgaaaaatc
    41881 aacatcgtca atattcaatt tccacagact gccgttacgg tttgtgacaa acgtccgctc
    41941 gccatcctcc gtcaccagtc caacgttaat tgaggtatct atgctgacgt cctgcttcag
    42001 gctttgaata tcaatattct ctttgcggca atggtcgaga ataaattgcc cggcggcatc
    42061 tttaccaata cgactcatta atgctgtgcg atggcccaga cgagaaataa ttgttgcttc
    42121 atttattgca tcacccccgg tggtcattgc gattctttca agaggataag aatccacatc
    42181 aaagatattt ttactgaccg gttgcaatgg aatatcaaca atagcggcac ctatacaaat
    42241 aacgtcgaga ttatccatat cattattccg ctttgccatc agaaccgaac agtttaattt
    42301 tttccaatgc ccgttctttt acagctttac gtacttcacg ttctaaatgc aggaaaggct
    42361 gatcctggtt ttctttcact gctaccattg cggcctgaca gagctccgta tgaatgttga
    42421 ttttcgcaat acccaacgaa attgcagttt taatgtcggc atcactgatc cccgatgcgc
    42481 cgtgcaaaac cagcggaaca gaaacagcat cgcgtacgcg tttgacgacc tcaaagttca
    42541 attgtggctc tgacgtataa accccatgct ggttgccgat ggcgacagcc aatgagtcac
    42601 agcccgtacg ttcaacaaat tcagccgcct ggtcaggatc ggtatagtga tagcccgcca
    42661 gcgcttcctc ataaacggtt tcattaccga catgccctaa ttccgcctct accggaatac
    42721 ccagcggatg gaagaaatca acagcctctt tggttaaacg aatattttct tcgaaatcaa
    42781 atgcggaagc atcacgcatt aatgaattca taccatgagt ccaggcgtta tgaataattt
    42841 ccatactccg accatgatcc caatgagtta ttaccggcac cgttgctttt tttgccattg
    42901 ataccatcat gtgagagaaa tcttcaaatg aggtgttccc gacaaaacct gtaccaaaag
    42961 aaataataac cggtgatttc gcttcttcgg ctgcgtcgat aacgcccatc aacatttctg
    43021 cattccatac gttaaaatgg gcaattgcat aatgtttatt tgtggcatcg ttttcccaat
    43081 atctgatatc tgcgagcata ttctgttctc ccgtattaat taatcgctaa ttttaataac
    43141 gcctttaata atgtcgcgtt tgttgttaac tgactcttca aatgcctgtt gtacatcccg
    43201 ataatcgtaa atatgcgtca ccatcgattt cacatcgaat cgccctgaag aaatagcttc
    43261 aatcgtgacc ggataacgat tggcatagcg gaataccgtc tggatagtga cttcgcgatt
    43321 gattttgagg aaattgattg ccgaatcgcc cggtacagta ccaacaatca taattttacc
    43381 gccgcgcatt accagataag gtgcctgttt aacggtgacc gcagaacctg ctgtttcgaa
    43441 aacaatatct gcgcccattt cttcggtaaa ttgctgacag cgtgcaatag tgtcttcttt
    43501 tgcgccgtta ataaccactg tcgcgccgag ctgttccgcc attgtcagac gtttttccag
    43561 cacatcaacg acggcaatat ccgtagctcc caggcatttg cacgcttgca acgtcatcaa
    43621 accaatacaa cctgctccca gaataattat cttcttaccc ggtttaacat ctgccagcat
    43681 cgcggcatgc atcccgactg cggcaggctc caccagcgcc ccttccatcg tgtccatatt
    43741 gtcgggcagt ttgtaagtaa agctctccgg atgacacaga tagtgcgtta atgcgccgcg
    43801 gtagttgggt tgtgtcgcca taaaatcaac gtccgggcag atgttatatt tgccttccag
    43861 acagtaacga cagtgaccgc aaggaacgcc aggttcgata tttacccgat cccccgcttt
    43921 aaatttgcgc acacggcttc ccacagccac aaccgtcccg gcgcattcat gacccaggcc
    43981 aatttcttga tttgggtctt taggcggaat aaacgggcct gattcgaaac catgtacatc
    44041 tgaaccacaa ataccgacat attccacttt aatcaaaact tcatcttctt taggcacagg
    44101 tatttctgct gaaataattt tcattgtgcc cggcacctgc aatattgctt ttgaattttt
    44161 cattttgaat ccaccagtat tatttattga ctactgcatc aatacttaaa ctttcaacgg
    44221 agacaccttt ggtttcaatt ccaatggtgg cgatagcaat tgcgacaata attgaaaccg
    44281 cccccagaag aataaagact cccgttacgc cataactact gagcagcact gcaacggcat
    44341 aaggtgcggc aataccactg attcgcccta ctgcattcgc cagaccggag ccacgtaatt
    44401 tggcctctgt cggccagatc tcagggacat acactgccga ggcatagcaa acgtacatat
    44461 agacgaaagt aatcaggaag aaaccaatca gcgttatgag caacatactg gtttgcagtg
    44521 aatagatata tccgagcacc gcaatcagga ttaatagccc cacccccatt gttttacgcg
    44581 gaattttatc catcaccagc atggcaataa aaataccaaa tggcgcgcca aacatactca
    44641 tggtatttaa aacaatcgag tcttttaaat taattccctg ggtcatgaat atcgttggca
    44701 accagttaat tagtgtgtac tgcacaacgt tcatggcaat cagcacacaa gaacctaata
    44761 tcacgcgttt cagtaatact cctgttagta aggctgaata cggcaccgct tgtggcgctt
    44821 taccgtcatc agcaataacc acgggcggca aaggttttcc cgtctggcgt atgacgcctt
    44881 cttctatact ccgcatgact ttctcggctt cctgataccg tccgcgcgat tccagccagc
    44941 gcggggattc aggaaagtag cgccaggcca gcgccgtagc gataagcgac aatattgcag
    45001 ggataagcag ttgtactcgc cagttccact ctgcactaat cagcggcgtg agtcccatcg
    45061 caatcaatga acagagcgga tatgaccagt tgccaataaa agaaacccga ctggaccacg
    45121 ttccgcgatt tctaccgggc atatattcgg tgaaaccagc aaacagcgtc accagtaaag
    45181 ctcccagccc aacgcccatc acaaaacggc aggcaataag gaaatccata ttcggtgaaa
    45241 agcaccgacc accatcgagg caatatgaat ggcctcatag aggatgaacg catttctgcg
    45301 accggttttg tcaccgatga tgccgccaac cagcgcaccg agaaacattc cggcggtcgt
    45361 gattgctgag aatgtggcag tggtggaatt atctgtccag cccaactctt tcagctgcgc
    45421 gaggatcaag ccaccaacgg cattactcca gcagacaagc aagccaaacg cgacgatagc
    45481 aaacattgac gaatgccagc ggcaatccgg taagcgatcc agccgagcac cacaatgcgg
    45541 ttttgttatc tgttccatgc gataacgttc cttcaggaga gtagttattc atcaaagtcg
    45601 taagtcatga tcactttgat tgcggtttta tcgaccatcg catcaaaccc ttcgcgccat
    45661 tgcgacaggc cgatacgatg cgtgatcatc ggtttgactt tgatagcgcc gctggctaat
    45721 agccggagag cgttacgcca tgaggtggag tcataggcca tatgcccaat gatgcttttg
    45781 ttccaggcgg taatgtcatt aatcgagaaa tcaagaggtt tgaagcccat tccaacgcgt
    45841 actacttccc cattcgggcg gagcatttcg atggcttgtt tcaatgcgat attggcaccg
    45901 gagcattcaa tcaccagccc cagattgtct ttgccacaaa tttgctggca gcgtgccacc
    45961 acatcttcgg tagaaccatt tactactgcc gtcgcaccca gttcttttgc aaccgggaag
    46021 cggaccgcca catcttcttg tagaccaacg acgacgatat ttaccgcccc cataatccgc
    46081 gccatttgta cggagaacag cccgagtggg ccagtaccga tgacgaccac atcctgacca
    46141 gggaggaatt tcgattgctg cgcgatggat ttgtaggcat tacagatagg gtcaagtacg
    46201 gctgcgtcct cataatcaac accatcaggg atttcccaca acgcatgacg atgaattttg
    46261 agaatttcac caggaaccag acaatatttg gaaaaaccac cgccccaggt attgttatcc
    46321 agaccaaggt gattttctgt acaacacaga aaatcacctt gttcacaggc cggacaaacg
    46381 ccgcagacgt gaccgctgtt atctgacacg acgcgttgcc ccactttcca gtctttgact
    46441 ttttcaccaa cctgcgcaat acaacctgcg aactcatggc cgcggataga gttaaactca
    46501 tcagaaccgc tatcgacatt gtagtgcttc atgtctgcgc cgcagattgc cgcggcttta
    46561 atttcaatca cgacatcttc cgggccacaa atgggttgtg ggacatcgat catcttgtag
    46621 ccgccaaagg ctttgccaaa ccgagccagt gctttcattg cgtcatcctc tgtgttttgt
    46681 tttgcttaga tggtcatcat acttacccac atgatttttg aggtcaacat taaatctgta
    46741 aaacacagat aatgatctgc gttttacaac tcagatcaca attacgcaga aaatggctgg
    46801 atctgttaca ggttgatgga aggcggaacg caaaatgagc aaatttgaga gggattaccg
    46861 gccaaatagg tctgagactt aagttcagga gaagtcattc aggcgtgaac gcgactgcaa
    46921 gagaccgggc tggggctttg cctggtcgtg acgagataat tgagatgagt cgtggggtta
    46981 ttgttggcta tcccctttat aaccgcggca aaaaggggac aaaccactta cttaaacatg
    47041 gcaataggct ttgctgagat accaaaatct tcttttaact gttgtttgct cttcatgacc
    47101 atctgaccat ttgtgtcaat tgtcatatgc tgtgcttcgg tattattgcg ggcttgccac
    47161 agcatcacca gttgcaggca gttctctttt tgttcctcgg tcaacgcaac gccatcaggc
    47221 catttcccca attcaacggc ggtcgacaaa cgctggtata cctcaggcgt catgctgttg
    47281 ataatgtcat caagattcat aatttttccg ctcctgtgga ataagttgct gaatcgtttt
    47341 ttcaaccgtt gatttcttcg ccgttttcgc catcggtaaa gcgtaaagag gcagagttaa
    47401 cacaataacg ttcgcccgtt ggctgcggcc cgtcggggaa gacatgcccc agatgggcat
    47461 cacagttacc gcaacgaatt tctatgcgct gcattccatg tgacaagtct ttgatataac
    47521 gaatggattc ttcactcacc ggttcgtaga aactgggcca gccacagccg gaatcatact
    47581 tggtttggga atgaaacagc ggggcatcgc agatcaaaca gtgatatacg ccgtcacgct
    47641 tgttatgcag taaacgaccc gtaaatggcg gctctgtccc atgattctgc gtcacgtaga
    47701 actgcatctc ggacaaattt tttttcagtt cttctgccga aggtttatta gccatttgct
    47761 cacatctcac tttaatcgtg ctcacattac gtgactgatt ctaacaaaac attaacacca
    47821 actggcaaaa atttgtccta aacttgatat cgacgaaatg gctgcaccta aatcgtgatg
    47881 aaaatcacat ttttatcgta attgcccttt aaaattcggg acgccgaccc catgtggtct
    47941 caagcccaaa ggaagagtga ggcgagtcag tcgcgtaatg cttaggcaca ggattgattt
    48001 gtcgcaatga ttgacacgat tccgcttgac gctgcgtaag gtttttgtaa ttttacaggc
    48061 aaccttttat tcactaacaa atagctggtg gaatatatga ctatcaaagt aggtatcaac
    48121 ggttttggcc gtatcggtcg cattgttttc cgtgctgctc agaaacgttc tgacatcgag
    48181 atcgttgcaa tcaacgacct gttagacgct gattacatgg catacatgct gaaatatgac
    48241 tccactcacg gccgtttcga cggtaccgtt gaagtgaaag acggtcatct gatcgttaac
    48301 ggtaaaaaaa tccgtgttac cgctgaacgt gatccggcta acctgaaatg ggacgaagtt
    48361 ggtgttgacg ttgtcgctga agcaactggt ctgttcctga ctgatgaaac tgctcgtaaa
    48421 cacatcaccg ctggtgcgaa gaaagtggtt atgactggtc cgtctaaaga caacactccg
    48481 atgttcgtta aaggcgctaa cttcgacaaa tatgctggcc aggacatcgt ttccaacgct
    48541 tcctgcacca ccaactgcct ggctccgctg gctaaagtta tcaacgataa cttcggcatc
    48601 atcgaaggtc tgatgaccac cgttcacgct actaccgcta ctcagaaaac cgttgatggc
    48661 ccgtctcaca aagactggcg cggcggccgc ggtgcttccc agaacatcat cccgtcctct
    48721 accggtgctg ctaaagctgt aggtaaagta ctgccagaac tgaatggcaa actgactggt
    48781 atggcgttcc gcgttccgac cccgaacgta tccgtagttg acctgaccgt tcgtctggaa
    48841 aaagctgcaa cttacgagca gatcaaagct gccgttaaag ctgctgctga aggcgaaatg
    48901 aaaggcgttc tgggctacac cgaagatgac gtagtatcta ccgatttcaa cggcgaagtt
    48961 tgcacttccg tgttcgatgc taaagctggt atcgctctga acgacaactt cgtgaaactg
    49021 gtatcctggt acgacaacga aaccggttac tccaacaaag ttctggacct gatcgctcac
    49081 atctccaaat aagttgagat gacactgtga tctaaaaaga gcgacttcgg tcgctctttt
    49141 ttttacctga taaaatgaag ttaaaggact gcgtcatgat taagaaaatt tttgcccttc
    49201 cggtcatcga acaaatctcc cctgtcctct cccgtcgtaa actggatgaa ttggacctca
    49261 ttgtggtcga tcatccccag gtaaaagcct cttttgcatt acagggcgca caccttctct
    49321 catggaagcc tgcgggtgaa gaagaagttc tgtggttgag caataacaca ccgttcaaaa
    49381 atggcgtcgc tattcgcggt ggcgtaccgg tttgctggcc gtggtttggt ccggctgcac
    49441 aacagggtct gcctgcgcac ggttttgccc gcaacctgcc gtggacgctg aaatcacatc
    49501 gtgaagatgc tgatggcgta gcgctgactt ttgaattgac acaaagcgaa gagacgaaaa
    49561 aattctggcc gcacgacttt acgctattag cgcatttccg cgtgggtaaa gcctgtgaaa
    49621 tcgatcttga agcacacggc gaatttgaaa ccacctctgc actgcatacc tactttaacg
    49681 tgggtgatat cactaaggta agcgtcagtg gactaggcga tcgcttcatt gataaagtga
    49741 atgacgcgaa agaagatgta ctgaccgacg gtattcagac cttccctgac cgtaccgatc
    49801 gcgtgtatct gaatccgcaa gattgcagcg taattaatga cgaagcgctg aatcgtatta
    49861 tcgccgtagg ccaccagcat catctgaacg ttgtaggctg gaacccagga ccggcgcttt
    49921 cagttagcat gggcgatatg ccggatgatg gctacaagac ctttgtttgt gtagaaacag
    49981 cttacgcctc agaaacgcaa aaagtcacca aagagaaacc tgcacatctg gcgcaatcca
    50041 ttcgcgttgc gaaacgttaa tttgcgttaa tgttgtgtgc cgggtgcgac gcatccggca
    50101 cgtatcaaca tcacaccata tccagcgcag tttttccttt tggtgccgga tatgccttat
    50161 ccagcatagc taattccgct gatgaaagtt cgacctcaag cacagccgca ttttgttgga
    50221 catgggcaat cgtggccgct tttggaatcg ccatcacacc ctgatgactg atcacccacg
    50281 ccaacaatac ttgtgccgcg ctgatattgt gagcatgtgc aatttcgttg actaccgcgt
    50341 tttttaacag cccattgcgc aaccgcccgg cctgggctaa cggactgtaa gccatcaccg
    50401 gcatctgctg tttctggcac cagggaagta gatcgtactc aatccctcgt gaaccgagat
    50461 ggtaaagcac ctgattagtg gcacactgat tcccccccgg cagctgccag agttcctgca
    50521 tatcggcata atcaaggtta gaaacgcccc agcggcggat ttttccctgg gcgatcaatt
    50581 tttccatcgc tgcgacagtc tcttcaaaag cgaaactgcc agaccagtgt aataagtaga
    50641 gatcgagata atcagaattg agacggcgta aactggcttc gcatgcattt atcgcttttt
    50701 gcccgccagc attccacgga tagactttag agacgagaaa gacgttatca cgcagaccga
    50761 ttaatgcttc cccaaccact ttttcggcac cgccatcggc atacatttcg gcggtatcaa
    50821 tgagggttaa accgagttca atgcccgcgc gtagtgcagc aacttctgtt ttacgctgac
    50881 tggcatcttc gcccatatac catgttccct gccctatggc tggcagtgag acatcgccac
    50941 taaattgaat cattttttgt tgcattgttt cctcccaggt attgcaccac cgtaatgcaa
    51001 aacagggcat gacgccctgt ttttatgcac aaaatgccct ggaaagatgc attatcagaa
    51061 tttgtaggtg atcccggtag aaatcaggcc agtccaggat ttatccacca ttgggctgtc
    51121 agtaacttca tcagacagac gggtgtagcg cgcggtaccg taaacactcc agtcgccgag
    51181 gaagttgtag ctggcgctca gctccaggta agggctccag ctgtcgttcg ggttatagcc
    51241 acgcagaccg ctgcgagcgg actctttgcg cgatacgcca taatagtatt cgttctggtt
    51301 ttcgctgttc cactgcacac caatacccgg agtcacggtc aggccaccgt tggtgtaacg
    51361 atacaaccag gccatatccc agatgatgcc gttgctgtta tccagggtat cgccagccag
    51421 ggtggtacgc aggtaaccgt actgggtaaa gtgagcataa gacagaccag ccatcatggt
    51481 gctcttacgg tcatccaggt gacgcatttg gtgatcgcca ctgtctttag ctttgaagta
    51541 aagcggcgac cagtaagcgg taattgaaag tttatccgtt gcgtcattcc acaggtagta
    51601 accaccacct aagccacgga accagaagtt atcgccttca tagttgatta ccggtactgg
    51661 gtagacatcg gtatcgtaat ctttatatgg gtgttcaacg acacctacgc ctgcgcccag
    51721 ggaaaattta ccttcagcgt gcgctacgcc tgcagacgtt gcgataagca ctccaagtgc
    51781 cagaagtttg agtttggtca caattaatca ttccttaaac aaatgtttag cgggcgacaa
    51841 agtttacccg tcaatacatc gaaacccaac ctttttacgt tttcattttt taaagtaact
    51901 gtttaatttt cctgacgcag atgacaccac gcttacagcc aaatgaattt agcgttaccg
    51961 gcgaccctat tgtttacatt aattatgcaa aatttatgga tgagttgttg atatgccatt
    52021 gaaattaaga aagccgtgca ggcaagtttt ccatttgcca tctacgctta attttgaagg
    52081 tgtatcaccg ggcacgttgt tctcatcgtc gataaaatgg catgagagtt gctgtgtttt
    52141 agcaagagac gtcgttcagt ttacctcttc cgggagcctc tactattcat atgaacggct
    52201 cttaacctgt gctaaaaaac gaaaggacgg cataccatga atatattcga tcactatcgc
    52261 cagcgatatg aagctgccaa ggacgaagag ttcacactgc aggagtttct taccacttgt
    52321 cggcaagatc gcagtgctta tgccaacgcg gctgagcggc tattgatggc tattggtgag
    52381 cctgtcatgg tcgatacagc ccaggaaccc agactttctc gactcttttc taaccgggtc
    52441 attgcacgtt atccggcgtt tgaagagttt tacggcatgg aagacgcgat tgaacagatt
    52501 gtctcctatc tgaaacacgc ggctcagggg ctggaagaga agaaacaaat cctgtatctg
    52561 ctggggcctg tgggtggggg taaatcatcg cttgctgagc gactgaaatc attaatgcag
    52621 ctcgtaccga tttatgtatt gagcgccaac ggtgagcgta gcccggtcaa cgatcatccg
    52681 ttctgtcttt tcaatccgca ggaagatgcg cagattctgg aaaaagagta tggcattcct
    52741 cgccgttatc tcggcaccat catgtcgccg tgggcggcaa aacgcctgca tgaatttggt
    52801 ggcgatatca ctaagttccg ggtagtgaag gtctggccgt caattctgca acaaattgct
    52861 atcgccaaaa cggaacccgg tgatgagaac aaccaggaca tctccgccct ggtagggaaa
    52921 gtcgatattc gtaaactcga acactacgcg cagaatgacc cggacgccta cggctattcc
    52981 ggtgcgctgt gccgcgccaa tcaggggatc atggaatttg tcgagatgtt taaagcaccg
    53041 ataaaagtgc tgcatccctt gttaaccgcc acccaggaag gtaactacaa cgggacggaa
    53101 ggtatctccg ccctgccgtt caacgggatt attctcgcgc actcgaacga atccgaatgg
    53161 gtcactttcc gtaataacaa aaacaacgaa gccttcctcg accgtgttta catcgtgaag
    53221 gtgccgtatt gcttgcgcat ttccgaagag atcaaaatct acgagaaatt gcttaatcac
    53281 agtgaattga ctcacgcccc ctgcgcccct ggcacgctgg aaacgctgtc acgtttttct
    53341 attctttcgc gtctgaaaga gccagaaaac tccagcattt attcaaagat gcgggtttat
    53401 gatggtgaaa gtttgaaaga cactgatccc aaagccaagt cgtatcagga atatcgtgac
    53461 tacgccggtg tcgatgaagg gatgaacggt ctgtcgacgc gttttgcgtt taagatcctc
    53521 tcccgcgtgt tcaacttcga tcatgtagaa gtggcggcaa acccggtcca tctgttctac
    53581 gtcctggaac agcagatcga gcgcgagcag ttcccgcaag agcaggcaga acgctatctg
    53641 gagttcctga aaggttatct gatcccgaaa tatgccgagt ttatcggcaa agagatccag
    53701 acggcctacc ttgaatccta ttccgaatat gggcaaaaca ttttcgaccg ttatgttacc
    53761 tacgcggatt tctggattca ggatcaggag tatcgtgatc cggataccgg gcagttgttt
    53821 gaccgcgagt ctcttaacgc cgagctggag aaaatcgaga aaccggcggg gatcagtaat
    53881 ccaaaagatt tccgcaacga gattgttaac ttcgtactgc gcgccagagc gaataacagc
    53941 ggacgcaatc cgaactggac cagctatgaa aaactgcgca cggttattga gaagaaaatg
    54001 ttctccaata ccgaggagct gttgccggtt atttcgttta acgccaaaac gtcaaccgac
    54061 gagcagaaga aacatgacga ctttgtcgac cgtatgatgg aaaaaggcta cacccgtaaa
    54121 caggtgcgtt tactgtgcga atggtatttg cgcgtacgta aatcgtctta acaaccctgg
    54181 cccggtacac ttgctaccgg gcctacaacg acagcgaacc gtgggccaga gaagcggcaa
    54241 cacaggcgta gcataccgtt ggcaaatgta gtacgggggg catatgacct ggtttattga
    54301 ccggcgtctg aacggcaaaa acaaaagcat ggtgaatcgc cagcgttttt tacgccgtta
    54361 taaagcgcaa attaaacagt cgatctccga ggccattaat aagcgttcgg tgactgacgt
    54421 cgacagcggc gagtccgtat ccattcccac ggaagatatt agcgaaccga tgtttcatca
    54481 ggggcgtggc ggtctgcgcc accgcgtgca tccgggcaat gaccatttcg tccagaacga
    54541 ccgaattgaa cgtccccagg gtggcggcgg aggttccggc agtggtcagg gccaggccag
    54601 ccaggatggt gaaggtcagg atgaattcgt ctttcagatt tcgaaagatg agtatcttga
    54661 tctgctcttt gaagatttgg ctttaccgaa tctgaaacaa aaccaacaac gccagctgac
    54721 cgaatataaa acgcatcggg cgggttatac cgctaacggc gttccggcca atatcagcgt
    54781 tgtgcgttca ttgcagaact cactggcacg acgcacagcc atgacggcgg gcaagcggcg
    54841 ggaacttcat gcgctggaag agcatttgac catcatcagc aacagtgaac ctgcgcaact
    54901 gctggaagag gaacgtctgc gcaaagaaat tgcagaatta cgtgccaaaa ttgaacgcgt
    54961 ccctttcatt gacaccttcg atttacgtta caagaactac gagaagcggc ccgatccctc
    55021 cagccaggca gtgatgtttt gcctgatgga cgtttccggt tcaatggatc agtccactaa
    55081 agatatggct aaacgttttt atattctgct gtatctgttc ctcagcagaa cgtataagaa
    55141 cgtggaagtc gtatacatcc gccatcatac ccaggcgaaa gaagtcgatg aacatgagtt
    55201 tttctactcg caggaaactg gcggcaccat tgtttccagc gccctgaaac tgatggatga
    55261 ggtagtgaaa gagcgttata acccggcaca gtggaatatt tacgcagccc aagcatcaga
    55321 cggcgataac tgggccgatg actctccgct ttgccatgaa attctggcga aaaaaatatt
    55381 acccgttgtt cgttattaca gctatatcga aattacacgt cgcgcgcatc agacactgtg
    55441 gcgagaatat gagcatctgc aatctacttt cgacaacttt gcgatgcagc atatccgcga
    55501 ccaggatgat atttatccgg tgttccgtga actgtttcat aaacaaaatg caacagctaa
    55561 agactaaaac tgtcagccgg gtcattatcg cctggctgat ttttagctca ctgtaaatta
    55621 tctcatttat tacatacatt agcttacaat cgctttaaat atgacagcat aacctttaca
    55681 caatttagtt ccagaaaaca atcattcgga aaaatgattc ggtcaacacg tatttccctg
    55741 gggttattct ttaattattt tttatcgtca acgaaaattg atcctggtca aaactatata
    55801 tctctgccat caataaaatc cagcactcac attgctctcc tttttatggc ttctatgggt
    55861 acacaaaaat taaaagctca aggctttttt attttcagct tattgctgac gttaatttta
    55921 ttttgcatta ctaccttata taacgaaaac acaaatgtaa aactcatccc acagatgaat
    55981 tacctgatgg ttgttgtggc tttgtttttc cttaacgccg tcatttttct tttcatgtta
    56041 atgaagtatt tcactaacaa acaaatttta ccaacactca ttttaagtct tgcattttta
    56101 agtggcctta tctatttagt tgaaaccatt gtaattatcc ataaaccaat caacggcagt
    56161 acactgatcc agacaaagtc gaatgatgtt tctattttct atattttccg ccaactcagt
    56221 ttcatttgtt taacctcgct ggcgctcttt tgttatggga aagacaacat ccttgacaac
    56281 aataagaaaa aaactggcat tctgttgctg gcgctgattc cttttttagt ttttcccctt
    56341 ctggcacaca atctgagtag ttataacgct gactattctt tgtatgtcgt cgattactgt
    56401 ccggacaacc atactgcgac ctggggaatc aactatacaa aaatattggt ttgtttgtgg
    56461 gcatttttac tgttctttat tatcatgcgt acacgattag ccagcgaact atggccgtta
    56521 atagcattat tatgtctggc atcgctatgc tgcaacttac ttctactgac tctggatgag
    56581 tataattaca ccgtctggta tatcagtcgc gggattgaag tttccagtaa actgtttgtt
    56641 gtgtcttttc tgatttataa catttttcag gaactgcaac tctccagcaa actggcagtt
    56701 catgatgtac tgaccaatat ttataatcgg cgctactttt tcaacagcgt agagtcatta
    56761 ttgtcgcgac ctgttgttaa ggacttttgt gtcatgctgg ttgatattaa tcagttcaaa
    56821 cgcatcaatg cccaatgggg acatcgtgtg ggtgataaag tgctggtatc aattgtcgat
    56881 attatccagc aaagcatccg ccccgatgat attttagcgc gactggaggg tgaggtgttt
    56941 ggcttgctat ttaccgaact caatagtgcc caggcaaaaa tcattgcgga acgtatgcgt
    57001 aaaaatgtcg aactcctgac cggctttagt aacagatatg atgttcctga acaaatgacc
    57061 atcagtattg gcacggtttt ttcaacgggt gacacgcata atatctcgct tgtcatgacg
    57121 gaagcagata aagccttacg cgaagcgaaa agcgaggggg gcaacaaagt gattattcat
    57181 catatttaag tgcaaaaata ttcagagcca tgctttttgc gtggcttttg catacaattt
    57241 attactatta cccctaaatt tcccctcccc agcggcgcag agatgagtat aattagcgcc
    57301 cctgtgccag gccgcaatcg aactttatct ggttttctcg tttcactaac cgaaggagtg
    57361 ccatttatca tgaaattgca ccatagaatg ctccggcatt ttatcgccgc aagtgtcatt
    57421 gtgctgacat cttccttcct tatttttgaa cttgtcgcca gtgacagagc aatgagtgcc
    57481 tatctgcgct atatcgtgca gagagcagac tcctcctttc tttatgataa gtatcagaat
    57541 cagagtattg ccgcgcatgt gatgcgcgcg ctcgctgctg agcagtcgga agtgtcgcca
    57601 gaacagcggc gcgccatctg cgaggctttt gagtctgcca ataataccca tggcttaaac
    57661 ctgactgccc ataaataccc tggcttacgc ggcacactac aaaccgcatc cactgactgc
    57721 gacacaattg tggaagctgc tgcactatta cccgcttttg atcaggcagt ggaaggcaac
    57781 cgccaccagg atgattacgg ttcaggtctt gggatggccg aagagaaatt tcactattat
    57841 ctcgatctca atgaccgcta tgtctatttt tatgagccgg ttaatgttga gtactttgcg
    57901 atgaataact ggtccttcct gcagtcagga agtattggca tcgatcgcaa agatattgaa
    57961 aaggtattta ccgggcgtac cgtattatcg agcatttacc aggatcagcg tactaaacag
    58021 aacgtgatga gtttgctgac gccggtatat gtcgcagggc agctaaaagg gattgtgctg
    58081 ctggatatta acaaaaacaa tctgcggaat atcttttaca ctcatgaccg ccctctcctc
    58141 tggcgttttc tcaatgtcac gctaactgat acagattcgg ggcgcgacat tatcatcaac
    58201 cagagcgaag ataatctgtt ccagtatgtc agttacgtcc atgacttacc gggcggcatt
    58261 cgtgtctcgt tatccattga tattctttac tttatcacgt cttcgtggaa aagcgttctg
    58321 ttctggattt tgacggcgtt aattttgctg aatatggtgc ggatgcactt ccgtttatac
    58381 caaaatgtgt cgcgagaaaa tattagtgat gcgatgactg gactctataa tcgcaaaatt
    58441 ttaacccctg aactggagca gcggttgcag aagctggtgc aatccggttc ttcggtgatg
    58501 tttattgcaa ttgacatgga caagttaaag caaataaatg acacccttgg tcatcaggag
    58561 ggggatttag cgattacgtt attagcgcag gcgattaaac agtcgattcg taaaagtgat
    58621 tatgccatcc gactcggtgg cgatgaattc tgcatcattc ttgtcgattc gacaccgcaa
    58681 attgcagcac aactgcctga acgtatcgaa aaacgtctgc aacatatcgc gccgcagaaa
    58741 gagatcggct tctcttccgg tatttacgcg atgaaagaaa acgatacgtt acatgatgcg
    58801 tataaagctt ccgatgagcg tttatatgtc aataagcaga acaaaaacag ccgttcatga
    58861 taaccttctg tagttgtttg cttgtaatct caggagcatg aaatgactga aatggctaaa
    58921 ggaagcgtga cgcatcagcg gttaatcgct ttattatcgc aagaaggtgc taacttccgc
    58981 gtcgttaccc atgaagcggt aggtaaatgt gaagcggtgt cagaaattcg tggcaccgct
    59041 ttaggccagg gggctaaggc actggtatgt aaagtcaaag gcaatggcgt aaatcaacat
    59101 gttctggcga tcctcgcggc cgatcaacag gccgatctga gccaacttgc cagccatata
    59161 ggcggattac gcgcttcgtt ggccagcccg gcggaagtcg atgaactcac aggctgtgtc
    59221 ttcggcgcga tccccccttt cagcttccat ccaaaactca aactggttgc cgacccccta
    59281 ctcttcgaac gatttgatga aatcgccttc aatgcaggca tgctggataa atccgttatt
    59341 ttgaaaaccg cggattattt gcgcattgcg caaccagaac tggtcaattt ccgccgcact
    59401 gcgtaactag cctgtccgtt cgataagaag aacggacaaa accagcacaa cagcaatggc
    59461 aaaaaacgat gacgtgataa tcagtgtctc gacgaacatt tgatcgttca tagtatgccc
    59521 ccgggagata gctgttttca cgttattgtt aacgtgcaca aatggcagtt tgatgacagt
    59581 tcgcctgatt ttttatgcaa aaaacgtaaa gattttctac ttccttcctg cagcaagcgt
    59641 aaagtaagca ggcttattat tctttggcaa ggaaaccacg atgtttgatg tcactttgct
    59701 gatcctgctc gggttagctg cgctgggctt tatcagtcat aacaccactg tcgccgtttc
    59761 aattctggtg ttaatcattg tccgcgtcac accgttaagc acctttttcc cgtggattga
    59821 aaaacagggg ctaagtatcg ggataatcat tctgacgatt ggtgttatgg ctcccatcgc
    59881 cagcgggacg ctaccgccct caaccctgat tcactcgttt ctgaactgga aatcgctggt
    59941 ggcaattgca gtcggcgtta ttgtctcctg gctgggaggg cgcggcgtga cgttaatggg
    60001 cagccagccg caactggtcg ccgggttgct ggtgggcact gttttaggcg tggcgctgtt
    60061 tcgcggcgta ccggttggcc cgcttattgc cgcgggtctg gtttcgctga ttgtggggaa
    60121 acagtagtta atcccgcaat atatcggcct ggcgtttgcc ccaggccttt cttaaacata
    60181 gtaataaagg ccgttgttga atcatacccc agcgtatgag caactttctg tacagtatcg
    60241 cctttcacta atccctgaag cgccataatc agctgtaact gctgacgcca ctggcgaaaa
    60301 ctcaaccccg tctctttcac tatcagccgg gcaagattgc gttcactcat cgcaaaaaag
    60361 cgagcccatt gccccaatga cccccactcg acgggctctt tcgccatcat ctccaccatc
    60421 gcgcggattt taggatgaga agaaacgggt aggtgcagct gttgttgtgg ctgctgaggg
    60481 agttcatcaa acaggacctg aattaatctg cgggtcatcg gctcagcacg ctgagtcgtc
    60541 gtcctgtttg ccagggttaa aattaattcc cggcataagg gcgatatttt caatgtgcaa
    60601 caggttgtcg gcattgtcac tgcgctgggt tcgataaaca gaaaacagag ttcggcgtta
    60661 gctgtcactt gattgctatg ttccacccct cccggtatcc aaaccgcata ttgcggcggc
    60721 accatccaca aagcattttc caccgtacag gtaattgcac catgtagcgc cagtatcagc
    60781 tgtcctttgc ggtgctgatg tacaggactg gttaactcat ccgttccggc gtgaatacaa
    60841 aatgcgaccg cggcttcatg gtgtcggtcg ggttcatagc cattgagatt caacctgtgc
    60901 atcattttgt ccgaatttag cgataatttg tcattttagc ttgattcaac ataacactaa
    60961 aaacggtaag gtacagcctc gtttgtaaca atgagaagca tatgacctgt tcaacttcat
    61021 taagcggcaa aaacaggatt gtccttatcg ctggtattct gatgattgcc acaacattac
    61081 gcgtcacctt taccggcgca gcaccgttac tggatacgat tcgttccgct tactcgctga
    61141 cgacggcgca aaccggctta ttgaccaccc tgccattatt agcctttgcg ctaatctcac
    61201 cgctggccgc cccggtggcg cgacgttttg gtatggaacg tagcctgttt gccgcgttac
    61261 ttttgatctg tgcaggtatc gcaattcgct ctctcccttc gccttactta ttatttggcg
    61321 gtacagcggt cattggcggt gggattgcat taggcaatgt cttactgcca ggattaatta
    61381 aacgcgattt ccctcattcc gtcgccagac ttaccggcgc atattccctg acaatgggag
    61441 ctgcggcggc actgggatcg gctatggtag tgccgctggc tttgaacggt tttggctggc
    61501 gaggcgcgtt gctcatgctg atgtgttttc ctctgctggc tcttttttta tggctgccac
    61561 agtggcgaag ccaacaacat gcaaatttga gtacttcacg cgccttacat actcggggta
    61621 tctggcgttc gccgcttgcc tggcaggtaa cattgtttct tgggatcaac tcactggtct
    61681 attacgtgat tattggctgg cttccggcga tcctcatcag tcacggctat agcgaagcac
    61741 aggcgggttc actgcatggt ttgctgcaac tagccacagc agctcccggt ttgctgatcc
    61801 cacttttctt acaccatgtg aaagatcagc gtggtattgc agcgttcgtt gccttgatgt
    61861 gcgcagtggg cgcggttggg ctctgcttta tgccagcgca cgcgatcacc tggactctgc
    61921 ttttcggctt tggttccggc gcaacaatga tactggggtt gacgttcatt ggtctgcggg
    61981 caagttctgc gcatcaggcg gcggcactct cggggatggc acaatccgtc gggtatttgc
    62041 tggcagcctg tgggccgccg ctgatgggta aaatacacga tgctaacggt gactggtccg
    62101 taccactgat gggtgttgca atactttcac tactgatggc gattttcgga ctttgcgccg
    62161 ggagagacaa agaaattcgc taatatccgg tgctatagtg acgtgacaaa tcatgcgtga
    62221 aagggagaac aaacacgatg aatattcagt gcaaacgcgt ttatgatccg gctgaacaga
    62281 gcgatggtta tcgcgtactg gtcgaccgcc tctggccgcg cggtatcaaa aaaaccgatt
    62341 tagcccttga tgagtgggat aaagaaatca cgccgtcaac ggaactgcgc aaagcctttc
    62401 acggcgaagt cgtcgatttt gcaacctttc gcgagcaata tcttgcagaa ctggcgcaac
    62461 acgagcaaga aggaaagcgg ctggcgaaca tcgccaaaaa acagccgctg accctgctct
    62521 actcagcaaa aaacaccacg cagaaccatg cgctggtgct ggcagactgg ctacgtagct
    62581 tgtgatttta gtacgccatc cggcggttat ttttcaccag ccggatggtc ccgtcgccac
    62641 aatgcccatt catcaatcgt ttcaccgccc ggtaatttgc aattgttgct gaccccttgc
    62701 gctgtctgca ctggaatgag cgtcccgccc ttctgctggc aatagaccga cgccggattt
    62761 gccataccaa tctgtggcgg tttaggtgct tctggctgag aaggggttga acaaccagcc
    62821 aggaccagca agcaaggcag aacaaaactg ataattttca tttattgatc tcacatattt
    62881 atccagactt agagtatcgc ggtatcgttt tgttttgcag cactattttt attacattca
    62941 ctcaaaacat attacgcctt gtttcatctt tgttgatgat gttttatcat gcctgcaaag
    63001 attaaataat cagcatttac ccgccgtatc ctggagttgt ttcgtgtcag atcagattat
    63061 cgcccgcgtc tcgcaatccc ttgccaaaga acagtcactg gaaagtctgg ttcgacagct
    63121 tctggagatg ctggaaatgg tcactgatat ggaatcaacc tacctgacca aagtggatgt
    63181 cgaagcgcgc ctgcagcata taatgtttgc ccgtaacagc cagaaaatgc acatcccgga
    63241 gaattttacc gtctcgtggg attactcgtt atgcaaacgc gccattgatg aaaactgctt
    63301 tttcagcgat gaagtccccg accgttgggg cgactgtatt gcggcacgca atcttggcat
    63361 caccacattt ctgagcacgc caattcactt accggatgga tcattctatg gcacgctttg
    63421 cgccgccagc agtgagaagc gccagtggag tgaacgcgcg gaacaggttt tgcagttatt
    63481 cgccggactg attgcacaat atattcaaaa agaggcgctg gtagaacagc tgcgcgaagc
    63541 caatgccgca ctgatagcgc aatcgtatac cgactcgtta accgggctac cgaatcggcg
    63601 ggcgattttt gaaaatctga cgacgctgtt ttctctcgcc cggcatctta accataagat
    63661 aatgatcgcg tttatcgacc tggataactt caaattaatc aacgatcgtt ttggtcataa
    63721 tagtggcgat ctgtttctca ttcaggttgg cgagcgcctt aatacgctcc agcaaaatgg
    63781 cgaagttatt ggtcgtctcg gcggtgatga gtttttggtt gtttcactga acaacgagaa
    63841 tacggatatt tcgtcgctgc gagaacgtat tcaacagcaa atacgtggag aatatcactt
    63901 aggtgatgtt gatttgtatt atcccggtgc cagtcttggc atagtagaag tcgatcctga
    63961 aacgaccgat gcagacagtg ccctgcatgc tgccgatatc gcgatgtatc aggagaaaaa
    64021 acacaaacag aaaacacctt ttgtcgcgca tccagcgcta cattcctgag gcgtattcac
    64081 atccttttga ttggtgataa catgcgaatc ggtattattt ttccgggtgt aatctttatt
    64141 acagcggtcg tatttttagc atggtttttt attggcggct atgctgcccc gggagcataa
    64201 agatgaaaaa aacaacgatt attatgatgg gtgtggcgat tattgtcgta ctcggcactg
    64261 agctgggatg gtggtaacgt cacatctaga aaatagcaaa ggctgcctgt gtgcagcctt
    64321 tgtgcaattt acgcgttaac ttttaatctt tctgtagata aacagcacga caatcgcgcc
    64381 aataacggca accacgaagc tgccaaaatt gaagccatcg actttaccaa agccaaacag
    64441 cgtgctgatc catccgccga ctacggcacc gactatcccc agcaggatag tcataaagaa
    64501 tccaccacca tctttacctg gcatgatcca cttcgccaga ataccggcaa taagcccaaa
    64561 aataatccat gacagaatgc ccattgtttc ctcacttatc tgttttgcat tagcgggtta
    64621 gtcgctgata aaaagcatag cacaacatcg ggagggcaag atttgtgacg agcatcacgg
    64681 aggaattttt tgcgatggcg cagaaattgc gccatcaacg atcagtgata attaccaacc
    64741 acaaacatca tgttcgtttt ccgtgtcata agaacgcacg gtattcacca gatcttttat
    64801 cacttcagcc gccacttctg gtaccagcaa agtcatcggc gtctctgttt cataatcgac
    64861 agaaacgcca ttgctgttat tggtgacggt cacggtatac gttgctttgc ccatgattca
    64921 tttcccgtta tgaatgactt tccgttgttg cgcgccttcc atcaggactt caggagcaac
    64981 gaagaagtca atgttgaaat aagtgtcgtc agtcatggct tcaatgttgt gccacttttc
    65041 tggagggaac accgcaaact gccccgcttc gataaggatc acttgatcag gctctgcact
    65101 gtgttcatca gcgtagccga gatatttgac cgccccatgc ataacggaaa ggcgtgggta
    65161 aacccccggg cgcgttcctt tatcaagatg acgttcgaat attccggcag gcgcagtttg
    65221 tttattccag aaaggcgttg agcgcgtatg aatataattc tgtgggattt gcagcatcct
    65281 tttccctcct tcggtgaatg cgctgaaaac ggtttattcc agccgtttca gggtacgcct
    65341 gataatttgc attttaaata ccatttattg gttacttttt agcaccgtat cagagaagaa
    65401 tcagggagga ttacagatgg gaagcccgcg acaacgcggg ctgaaagcat caggattgca
    65461 gcgtcgccag tcgggcggcg aaacccacga acatcaaacc aatcagtgag ttgcccactt
    65521 tagccagttt ctttttggta cgtatgtact gtgtgacaaa agcaccagaa ataatcagga
    65581 agctcaaata gcagaaactc accagttcca gcgtcgtcgc cagaataaag aatgaaattc
    65641 ccgtatgtgg ggcattaaca tcgataaact gtacgaaaaa cgacacatag aacaaaatgg
    65701 ctttcggatt agtcaggctc aaaattaacg cgcgtttaaa aatggcaccg tattgaggct
    65761 catcggattt ggcctcgtta tttttaccct tcagggtcgc gtagagaatt ttactcccca
    65821 gatagagcaa ataaaacgca ccaagataac gtacaatgtt gaataatatc ggggtggtct
    65881 taattaatgt cgccactcca gcccatgcca gaaacatcaa taccgcatcg ccaataaata
    65941 caccacaggc cgcaagataa ccgcctttca taccgctact gacgctattt ttgagtacaa
    66001 acagggtatt tggccctggc accaacacaa taaaaatggc cccaaccaga taggtccagt
    66061 aattcagaac cccgtattca gcgaacacat taacctcttt aattatcttt cgatcatgcg
    66121 cgattaaagg tgaatatgct aaccaatctg tagcggctta gaaaggagaa aatcaggttt
    66181 taacccgata tcaacgcgat aattgaatca ttaatcaggc atgctccagt gaaaaattcg
    66241 ggtagtgctc ggcaaaatac tggcgtaaaa attctaccgt tatccgcact ttcgctgacg
    66301 tcgccagcct tgaaacataa acggcccaga cgttcgctgg ctggtaatat tccggtagca
    66361 cttgcactaa atgaccactg gcaatgtttt cgctaacatc ccaccaggag cgcagagcaa
    66421 tcccctgccc atcgagacac cactgatgga caatttctcc atgattagac gacagtgggc
    66481 cggtaacttt aatcgcatgg tggccttctt tattgcgtaa ttgccagaca ccaaaaggat
    66541 gatcgcgctc tttaatgacc aggcacggca atgcagaaag atcggttaaa tgtttcggcg
    66601 cgccatgttg cgcaataaat tccggtgacg cgcagagaat gcgataattg gtcgccagtt
    66661 tgcgggcgat taaattaggg gcgatatcat cgccaatgcg aatatcgaga tcgacacctt
    66721 cattgaccaa atcgaccaac cggtcttcca catcaaaacg taattccagt tgcggatacg
    66781 ccttcgccag cgctgataac gccggagcca ccacctgtcg tccaaaacca aagctgctga
    66841 taatacgcag catcccctgt ggcacctgac gcacgtcaga aagttcgtcc atcatctgac
    66901 cgacatcctg caaaatccgc tgcgcccatt cataaatccg ctctccttct tcggtaatgg
    66961 tgacgcggcg ggtggtgcgg tgtaacaaca ccacgtttag cgtttgctcc agcaaggcga
    67021 tgcgcttgct gacgaacgcc ggagaaacgc ccaattcttc tgccacggcg gcaaaaccag
    67081 cccggcgagc caccagcata aagacgcgca aatcgttcag cagcggtaaa ttattcatga
    67141 ttcgtgtttt atgtttcacc agttacaggg attaattcct tttcagtcaa ttataggatg
    67201 gtgatgttgt caattttgat ggtcaggaag tgagaaccca atgatgaaaa cgatccgtat
    67261 tgctgcgatc ccgggagacg ggattggcaa agaagtcctt cctgaaggga ttcgcgtgtt
    67321 aaaggctgcc gctgagcgct ggggcttcgc cttgagtttt gagcaaatgg agtgggcgag
    67381 ctgcgagtat tacagccatc acggtaaaat gatgccggac gactggcatg agcaacttag
    67441 ccgtttcgac gccatctatt ttggtgccgt cggctggccg gataccgttc cggaccatat
    67501 ttcgttgtgg ggttcgctgc tgaaatttcg tcgtgagttc gaccagtacg tcaacctgcg
    67561 cccggttcgt ctctttcctg gcgttccctg cccgctggcg ggaaaacagc ctggcgacat
    67621 cgatttttac gtggtcaggg aaaacaccga aggcgaatat tcctcgctcg gcggtagagt
    67681 gaatgaaggt acagagcatg aagtcgtcat tcaggaatcg gtatttacgc gtcgtggtgt
    67741 cgatcgcatt ttgcgttatg cctttgaact tgcacaaagc cgcccacgta agacgctaac
    67801 ttctgccact aaatcgaacg gtttagccat cagcatgccg tactgggatg agcgagtgga
    67861 agcaatggcc gagaattacc cggagatctg ctgggacaag cagcatattg atattctctg
    67921 cgcgcgtttt gtgatgcagc cggaacgctt cgatgtggtg gtggcgtcca atttgtttgg
    67981 cgatatcctt tccgatcttg gcccggcctg caccggtacc attggcattg ccccatccgc
    68041 caacctgaat ccggaacgca ctttcccgtc gctcttcgag cctgtccacg gttccgcgcc
    68101 ggatatctac gggaaaaata ttgctaaccc tatcgccaca atttgggccg gtgcaatgat
    68161 gctcgatttt ctcggcaatg gcgatgagcg tttccaacaa gcgcataacg gtattctggc
    68221 cgcgattgaa gaagtgatta ctcacgggcc gaaaacacct gatatgaaag gcaatgccac
    68281 cacgccacag gttgccgacg cgatttgcaa aattattttg cgttaaggtc aaaccagttt
    68341 atttgaaccg cgtcactgac gcggtttttt tattcgttct tttcagtaaa taacctgcgt
    68401 catttcacct tttattgttt ccgtttcgtg ttttatggct ttccgtattc ttaattgttt
    68461 aatttatgta acatgcaaat aatcaatttg ttaaacacaa catacaactc attaccctgc
    68521 aaataattac aactggcaaa agccagagac gggcttttat gcccaggaga tgactcatga
    68581 tgagcaatgt taagaaaaaa gatgtgccgc tgataagcat cagtctggtg gccattcttt
    68641 tcatcgcagc tgcattaagc cttttcccac aacaatcggc cgacgcggcc aacgctatat
    68701 acacttttgt tacgcgtacg ttaggttccg ccgtacaggt attggttttg ctggcaatgg
    68761 gactggtgat ttatttagcc accagtaaat acggcaatat tcgtcttggc gaaggaaaac
    68821 cggaatacag cacgctctcc tggctgttta tgtttatttg tgccggttta ggttcttcta
    68881 cgctttattg gggggttgct gaatgggcct attattatca aacccctgga ttaaatatcg
    68941 caccgcgttc acaacaggca ctcgaattta gcgtccctta ctccttcttc cactggggca
    69001 tcagcgcctg ggcaacttat acgctggcct cattaatcat ggcttatcac tttcatgtgc
    69061 ggaaaaataa ggggctgagc ctttccggca ttattgctgc tattaccggc gttcgcccgc
    69121 aaggcccatg gggaaaactg gtcgatttga tgttcctgat cgccactgtc ggcgcactga
    69181 ccatttccct tgttgtcacc gcagcaacct ttacccgtgg gctttccgcg ctgaccggtt
    69241 tacccgataa tttcaccgtg caggcatttg tgatcctgct ttccggcggc attttttgcc
    69301 taagctcgtg gattggtatc aacaacggtt tgcaacgtct gagcaaaatg gttggctggg
    69361 gcgcgttcct gctgccatta ctggtgctca ttgtcggccc aaccgaattt attaccaaca
    69421 gcatcatcaa tgccatcggc ctgaccacgc aaaacttcct gcaaatgagc ttattcaccg
    69481 atccgcttgg cgatggttca tttacccgca actggaccgt tttctactgg ctgtggtgga
    69541 tctcatacac ccctggcgta gcaatgtttg tcacccgcgt ttcccgcggt cgtaagatta
    69601 aagaagttat ctggggactg atcctcggca gcaccgtcgg ttgctggttc ttcttcggcg
    69661 taatggaaag ctatgccatt caccagttta tcaatggcgt aatcaacgtc ccacaggtgc
    69721 tggaaacact gggcggcgag acagctgtgc agcaagttct gatgtcgttg ccagccggta
    69781 aattgttcct cgccgcatac ctgggcgtga tgattatttt ccttgcctcg catatggatg
    69841 cagtggccta caccatggcg gcaaccagta cgcgtaatct ccaggaaggt gacgatcctg
    69901 accgtgggct gcgtcttttc tggtgcgtgg taattacctt gatcccgctt tcaattcttt
    69961 tcactggcgc gtcgctggaa acgatgaaaa ccaccgtcgt actcacagcc cttccgttcc
    70021 tcgtcatttt actggtgaaa gtcggcggat ttattcgctg gctgaaacag gattacgccg
    70081 acattccggc tcatcaagtt gaacattatc tcccgcagac accggttgaa gccctggaaa
    70141 aaacaccagt gctccctgcg ggaaccgtat tcaaaggcga caactgagcg ccatcatcct
    70201 aacgataaag gtatccctat gagcaatctg agccctgact ttatactacc cgaaaatttt
    70261 tgcgctaacc cgcaggaggc gtggaccatt cctgcccgtt tttataccga tcagaacgcc
    70321 tttgaacacg aaaaagagaa cgtcttcgcc aaaagctgga tttgcgtcgc tcatagcagc
    70381 gaactggcga atgccaatga ttatgtgacg cgtgagatca ttggcgaaag catcgtgctg
    70441 gtacgcggtc gtgataaggt tttgcgcgcg ttctataacg tgtgtccgca ccgtggtcat
    70501 cagttgttga gcggtgaagg aaaagcgaaa aatgtgatta cctgcccgta tcacgcctgg
    70561 gcattcaaac tcgatggcaa cctggcccat gcacgtaact gcgaaaacgt cgccaatttc
    70621 gatagcgaca aagcgcaact ggttccggtg cgtctggaag aatatgccgg attcgtcttc
    70681 atcaacatgg accctaacgc caccagcgta gaagatcagt tacccggtct gggcgcgaaa
    70741 gtgctggaag cctgcccgga agtccacgat ctgaaactgg cggcccgctt taccacccgc
    70801 acgcctgcca actggaagaa cattgtcgat aactatctcg agtgctatca ctgtggtccg
    70861 gcgcatccag gtttctccga ctccgtacag gttgatcgtt actggcacac catgcacggt
    70921 aactggacgc tgcagtacgg tttcgccaaa ccgtccgaac agtctttcaa attcgaagag
    70981 ggcacggatg cggcattcca cggtttctgg ctgtggccgt gcacgatgct gaacgttacc
    71041 ccaatcaaag ggatgatgac ggtcatttat gaattcccgg tggattctga aactaccctg
    71101 caaaactacg atatttactt caccaatgaa gagttaaccg acgagcaaaa atcgctgatt
    71161 gagtggtatc gcgatgtgtt ccgtccggaa gatttacgtc tggttgaaag cgtacagaaa
    71221 gggctgaaat cgcgtggcta tcgtggtcag gggcgcatca tggccgacag tagcggtagc
    71281 ggaatttccg aacatggtat cgcccatttc cataatctgc tggcgcaggt gtttaaggac
    71341 taatgacatc agcggcggta ttttccgccg ctgggctgat ttttgatgga gtacagcaat
    71401 gtcagactat caaatgtttg aagtacatgt gaaccaaatt gaaccgctta ccgaacaggt
    71461 gaaacgcttc acgctggtgg caaccgatgg caaaccatta cctacgttta ccggaggaag
    71521 tcacgtcatt gtgcagatga gcgatggtga taacgagtac agcaatgcgt attcactact
    71581 gagttcgccg catgacacct cttgttatca gattgccgtt cggctggaag aacactcgcg
    71641 cggcggttcc cgctttttac atcagcaggt aaaagtgggc gatcggttaa cgatttcaac
    71701 gcctaataac ctgtttgcgc taattccctc ggccagaaag catctgttta tcgcgggcgg
    71761 tattggtatc acccctttcc tgtcgcacct ggcagagttg caatacagcg acgtcgactg
    71821 gcagttacat tactgctcac gaaatccaga aagttgcgca tttcgtgatg agctagtcca
    71881 gcatccgcag gctgagaaag ttcattttca tcactcatca accggaacac gactggaatt
    71941 agcgcgatta ttggcggata tcgaacctgg cacacatgtt tatacctgtg gccccgaggc
    72001 gctaaatgag gaggtaagaa gtgaagctgc gcgtctggac atcgccgccg atacgatgca
    72061 ctttgaacaa tttgcgattg aagacaaaac cggcgatgca tttaccctgg tgcttgcccg
    72121 ttccggaaaa gagtttgtgg tgccggaaga gatgactatt ttgcaggtta ttgaaaataa
    72181 taaagcagcg aaagtggaat gtttatgtcg tgaaggggta tgcggaacct gcgagacggc
    72241 aatactggaa ggtgaagctg accatcggga tcagtatttt agcgatgaag agcgtgccag
    72301 ccagcaaagt atgttgatct gttgttcgcg cgcgaagggt aaacgcctgg tgttggattt
    72361 gtagtttgcc gaagccggat gtggcgctga gcgcacccag tccggcttcg gaagatttta
    72421 ctgcggatat tcctgcaata aattgtgtaa tgcttccgcc atcagctcac cacgccagcc
    72481 ggaaatcagc tccggcaaat tgttctgcgg tttcagtttc cagtgccagt tcagcagttg
    72541 gttgatttgc cgacgcgatg ccagcaattc ggcgctgatc ttgtgcgttt cgctcacgtc
    72601 agtaatcagc gacttaatcg ctttaaacgc tttacgataa cccggcatgt ccatcaggtt
    72661 aagcatcggc tgcggtaagg cctcttccgg caatgtctgc gctttttcca ccagcgccag
    72721 cagcgtttta ccgtgaaagc ggatttcgct accggataaa cccaggctgt ccagttcgcc
    72781 taaacttccc ggcatataac gcgctacaga ccacaaatgc tcttcacgca cgacaaagtt
    72841 cactgccaga tcgcgctccc gagccttgcg cagtcgccaa tcggctaaca gttgcagaca
    72901 ggccagttgg cgtgtgcgta actgccaggc attggtgata tcacgccagg catcttccgg
    72961 tgcaacgact tcctgacgac gcatttgcat caggcggcat tcatccagcg ccgcaggtag
    73021 ccagccggag gcctccgttt ctaccataag ttttgcggtg atcggtaaca gataccagac
    73081 atccgccgct gcgtattcac actgacgttc ggtcagcggt ctggccagcc agtcggtgcg
    73141 cgattcactc ttgtccagcg taacgccgga atactcttcc accatggaag cgaaacccca
    73201 tgacatcggg cgtccgcaga aggcagcaag gatttgcgtg tcaatcaagg gttgtggtaa
    73261 ttcgccaaag acattgagga acacttccag atcttcactg cctgcatgga gaaattttgt
    73321 gatggacgga tcgcgcagga tcgctttcag tggtgaccag tcggagatcc cgagaggatc
    73381 aattagcgcc agatgctcac catcaaaaag ttgaattaga cccagttgcg ggtaataggt
    73441 gcgcgtacga acaaattcag tatccagggc tatcgccgga aaggcacgga cggcttcaca
    73501 caaagaagcc agcgcatcgt ccgtggtaat catttggtaa ttcaaattgt attctcttta
    73561 gtgggcgtca aaaaaaacgc cggattaacc ggcgtctgac gactgactta acgctcaggc
    73621 tttattgtcc actttgccgc gcgcttcgtc acgtaattct cgtcgcaaaa tttttccgac
    73681 gttagatttc ggtaactcat cacgaaactc caccagcttc ggtactttgt agcccgtgag
    73741 ctgacggcgg caaaaggtca ccagtgactc ttcggtaagc gatggatctt ttttcactac
    73801 gaagattttc accgcttcac cactggagcc ggaaggtacg ccaacagccg cgacttcctg
    73861 tacgccagga tgctgcatga cgacatcttc aatctcgttg ggatagacgt taaaaccgga
    73921 aaccagaatc atgtcttttt tacgatcgac aatgcgcagg aatccttctt catccatcac
    73981 cgcgatgtcg ccggtgtgta accagccatt tttgatgatt tcatcggtag catccggacg
    74041 ctgccagtaa cccagcatca cctgcggtcc tttgacacaa agctcacctg gttgacccgg
    74101 tggtacttcg ttgtcgtcgt catccaccag tttggcttcc gtcgacggca ccggcaaacc
    74161 gatgctacca ctatgataat caatatcata cgggttaacg ctgaccagcg gcgcacactc
    74221 ggtcaggcca taaccttcca gcagatactg tccagtcagt ttcacccaac gttctgccac
    74281 cacttgctga acaggcatcc ctccgcctgc ggaaagatgc agactggaga aatccagctg
    74341 ctggaactct ttattgttca gcaacgcatt gaacaaggtg ttaacgccag tgatagcggt
    74401 aaacggatat ttcgctaact cttttaccaa ccctggaata tcgcgcgggt tagtgataag
    74461 caggttctgc ccacccagtt cgataaacag caggcagtta atggtcaggg caaaaatgtg
    74521 atacagcggc agcgccgtca ccaccagctc tttgcccgga tgcaacagcg gaccataggt
    74581 cgcgttaacc tgttccaggt tcgccagcat attgcggtga gtcagcatcg cgcctttcgc
    74641 cacaccagtg gtaccgccgg tgtattgcag gaaagctaaa tcttccggca ccagttcggg
    74701 tttgacgtac tgcatccggt agccgctgtg cagggcgcta cgaaatgaaa tggcatctgg
    74761 cagatggtat ttcggcacca gacgcttgat gtatttaaca acgaaattga ctaccgtgcc
    74821 ttttgccgta gatagctgat cgcccatacg ggtcagaatt acgtgctgaa cggcggtttt
    74881 atcaaccact ttttccagag tgtgggcaaa gttagacacg ataacaatcg ccgatgcgcc
    74941 gctatcgtta agctgatgct caagttcacg cggggtatac aacgggttaa cgtttacgac
    75001 aatcatcccg gcacgcaaaa tgccaaacag cgccaccgga tattgcaata aattaggcat
    75061 catcaacgca acgcgatcgc ctttcttcag tcccaaccct tgttgcaaat aagcggcaaa
    75121 cgcgcgactg cgttcttcca gtttgcggaa ggtcatcacc tcccccatat tcacaaacgc
    75181 gggttgatcg gcgtagcgcg cgaccgactg ctcaaacata tctaccagag attgataacg
    75241 gtcagggttg atctccgtcg gaacgtccgc gggataacgg ttaagccaaa ccttcttcaa
    75301 ttcttcacct ctaaaatgcg tgttcgtcgt catcgcaacc ccaaatgata tacatgttgt
    75361 taacataata ttaactcatc ataccagctt gataattacc caacgaaaag gttgcgaagc
    75421 gcgtcactat ttatttttat ctttaccgta agaatgcaga aacagcggac cagccgctgt
    75481 ttctttttct ttaaaaacaa gcaattattc agttacaact gtttgtactc tcgcggggcc
    75541 gggattatac cagccccatc cgccgtagcc atagggccag ccacgaccgc cataaaacca
    75601 tggatcaatc ggctgaggcg gcataatcac ctgctgggtt aaatgccaac gtttgtaacc
    75661 tgttgcctgc atcaccataa atttataggg cgtgttgccg atttttccgt caaccgtacc
    75721 ggtgattggc ccgacaactg tcaccagctg cccacggaaa tcgaccggat caagaaaacc
    75781 attcacatcg gcataaatgc ggccgcgaga aggttctccc agcgtcggtc tggctccgct
    75841 gtccagtggt acggtggcaa tttccaggcg ggttttccct tgctggtttt gtaccgcaac
    75901 cactttgccg ccaaagcgtg cctcctgacc aacgtacagc tgcggcgcac tcatcacccg
    75961 aactaaatct tgttgcggcg tgggactgct gcctttaatg gcgtccggca cagtaacaca
    76021 accgctgagc attagcgcaa acgtacctgc cagtatgcct ttgataacat tcttttgaac
    76081 cgccatgatg cgactccttt tttctcaggg catactctta agattcattc tttgcccgga
    76141 agtttcttcc atgcgacgtt gttacgtaaa taaaccggtt cggcatgttc caccgccacc
    76201 gttttaccct cggcaaacat ctggcaggca atcggcagca tatcttctgc agcgggcagt
    76261 aacacttcgc catcgcacag ggccaaaccg ctctctttac cgagatccgg ccaggcttgc
    76321 cagcccgtcc ctaccgtcac ccattcgccg gaaagctgtt gcatccgttc atgaacgagt
    76381 tcaggtttga gtacggcttc ggtttcttca ccgtgccaga taccgttttc atcacgctga
    76441 tattcggccc agtaaacttc gcccattcgc gcgtcaatgg ctgccagcac gcgtgttgcg
    76501 ccgtttttgc gccacgcccc ttgcgccatc gtcattagcg tggagacgcc aatcatcggt
    76561 aattccgcgc caagcgccag cccttgcgcg atgccaatac caatgcgcac gccagtaaag
    76621 ctaccggggc cgcgcccgta agccagagca tttatgtccg tcagggaagt tccactggtg
    76681 gtcaggatat cctgcaccat cggtaagatt cgttgagtat gttcacgagg gcaaagctca
    76741 aaatgagcgt tgacagtacc gtcgttccac agggcgacag agcaggcctc tgtcgcggta
    76801 tcgatagcca gaattcgcat gggtcttcgt gcttagatca ataaaaaggc gcgcatcata
    76861 ccatactcca tcacaaatta cctggaggat ggtatcgcaa ggaaacgaac cgcacgggca
    76921 atgtcacggg tgcgcggcgc tggcggcaga ctggcgagaa acgtcgcgcc gtaagggcgc
    76981 atcaccagcc gattgtcgca aatcactaac acgccgcgat cgtcggcgtc gcgaatcaat
    77041 cgccctaccc cctgcttgag agtaatgacc gcatccggca gttgtacttc atcgaacgga
    77101 tcaccaccgc gcaaacggca atcttccatg cgtgctttta atagtggatc atccggcgag
    77161 gtaaacggca atttgtcgat aatcaccaat gacaatgtat cgccacgcac gtccacccct
    77221 tcccagaaac tgctggttgc cacaagaagc gcgttaccgg cgctgacaaa ttgctgcaac
    77281 agttgccctt tgctggtttc cccctgcaac aaaacgggaa gcgtcatggt agcgcggaac
    77341 tgctcggcca gatcgcgcat catggcgtgc gaggtacaaa gcataaaaca acgaccgttg
    77401 ttagcttcga tgatcggtcg cagcattgcc gccagttgcc gtgcggaacc cggttgattg
    77461 gtttgcggca ggttgcgcgg cacacagagt aacgcctggc ggctgtaatc aaaggggctg
    77521 ggtaacagca acgactctgc ctgttcaatg ccaagccgcg aggtgaaatg atgcagatcg
    77581 tcgttcaccg acagcgttgc tgaggtaaag atccagctac cgggtttttg cgccattaac
    77641 tctttgaatt tatccgccac gctgagcggc gtgagtgcca gagtaaaatg gcgcgaagtg
    77701 cattcgtacc agtagctgta gcccggctga ttgatctctt ttagccgttt cagccgcgta
    77761 cgatacaacg tggcgcgctc aaatgccgca tccagcaagg cggaacgccc cagcgacagt
    77821 ttcgccacgt cataacaaag ttccagggtg tcatcgagca gtaaaaacgc ccgttgaatt
    77881 tgcggattag ctaacagttc gcgcaggttg ccacgataac caggctcacc gagttgcagg
    77941 cgaaaatcct gcgcgctctg ggcaaggcgg tcggcgcact tttgtaactg ctgagtatct
    78001 tttaattcgg tgcgataggc gatggtgatg tcttttgcca ggtcgagcag ttgtcgactg
    78061 gagagtgact gaccaaaata ctggctggca atgtcgggca gttggtgggc ttcgtcgaag
    78121 atcatgacgt ccgcttccgg gatcagttcg ccaaaaccgc tctctttcac caccatatcc
    78181 gccagaaaca gatgatgatt caccaccacc acatcggcgt ccatcgcttt tttgcgtgct
    78241 ttgaccacaa agcaatcttt atacatcggg cagtcgctgc caaggcagtt atcgttggtg
    78301 ctggtgacca gcggccacgc ctgtgaatct tccgccacgc tgacgcaggt gctgatatca
    78361 ccatcgactg tttgattaga ccaggagcgc agcaggatca catcgcttaa gatttgtacc
    78421 ggcagatcgc cccccgccag cgcctgctgt tcgagacgtt cgaggcagag gtagtttgag
    78481 cgccctttca gcaacgccac gttgcccgtg tatttcaatg cctttgagac cgttggcaaa
    78541 tcgcggctgt agagctgatc ctgcaacgct tttgaaccgg tcgagataat gactttcttt
    78601 ttcgcccgca gcgcaggagc caggtaagcg taggttttgc ccgtaccggt tcctgcttcc
    78661 accaccagcg gctggccttt ttctatcgcc tgggtgacgg ctaccgccat ctgtcgctgt
    78721 ggttctcgcg gcttaaagcc tggtatcgct ttcgccagct gaccatctgg tgcaaaatcg
    78781 tccgtcacac taccccctgt tgatttgaac agggattatg tcaggatgag ggcgctttcg
    78841 ccagttgaag tggtgacggc gacctcacat tgtggcagtc tttgcagcac gaaaatggaa
    78901 gtataatgag gacaaaatga tgactatcgt tcgtatcgat gctgaagccc gctggtctga
    78961 tgtggtgatc cacaacaaca cgctctacta cactggtgta ccggaaaacc tcgacgccga
    79021 tgctttcgag caaactgcca acacgctggc gcaaattgac gccgtgctgg aaaaacaggg
    79081 cagcaataaa tcgagcattc tggatgccac cattttcctg gccgataaaa acgacttcgc
    79141 ggcgatgaat aaagcctggg atgcctgggt tgtcgcgggt catgcgccgg tgcgctgcac
    79201 ggtacaagcg ggtttaatga acccgaagta taaagttgaa attaagattg tggctgcagt
    79261 gtaagcttta tcgaagcata ataagtcaga cgataattta tcgataata
//
LOCUS       DADXDL010000011        69527 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.011, whole genome shotgun sequence.
ACCESSION   DADXDL010000011 DADXDL010000000
VERSION     DADXDL010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 69527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 69527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..69527
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.011"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            12..962
                     /locus_tag="IRB70_000981"
     CDS             12..962
                     /locus_tag="IRB70_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000188400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20/M25/M40 family metallo-hydrolase"
                     /protein_id="HBC0630928.1"
                     /translation="MILILFSLPLIIFYQPWVNALPPTPRHASPEQLEKTVRYLTQTV
                     HPRSADNIDNLKRSAEYIKEVFISSGARVTAQDVPITGGPYKNIVADYGPADGPLIII
                     GAHYDSVSSYENDQLTYTPGADDNASGVAGLLELARLLQQQAPKTGVQLVAYASEEPP
                     FFRSDEMGSAVHAASLERPVRLMIALEMIGYYDSAPGSQDYPYPAMSWLYPDRGDFIA
                     VVGRMQDINAVRQLKAALLSSQDLSVYSMNAPGFIPGIDFSDHLNYWQHDIPAVMITD
                     TAFYRNKQYHLPGDTADRLNYQKMAQVVDGVITLLYNSKQ"
     gene            1062..1565
                     /locus_tag="IRB70_000982"
     CDS             1062..1565
                     /locus_tag="IRB70_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbM family protein"
                     /protein_id="HBC0630929.1"
                     /translation="MGMIGYFAEIDSEKINQLLESAEKPLMDNIHDTLSGLRRLDIDK
                     RWDFLHFGLTGTSAFDPAKNDPLSRAVLGEHSLEDGIDGFLGLTWNQELAATIDRLEA
                     LDRNVLRKQFSIQRLNEMEIYPGVTFSEELEGQLFASIMLDMEKLISAYRRILRQGNH
                     ALTVIVG"
     gene            complement(1632..3089)
                     /gene="nuoN"
                     /locus_tag="IRB70_000983"
     CDS             complement(1632..3089)
                     /gene="nuoN"
                     /locus_tag="IRB70_000983"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoN"
                     /protein_id="HBC0630930.1"
                     /translation="MTITPQNLIALLPLLIVGLTVVVVMLSIAWRRNHFLNATLSVIG
                     LNAALVSLWFVGQAGAMDVTPLMRVDGFAMLYTGLVLLASLATCTFAYPWLEGYNDNK
                     DEFYLLVLIAALGGILLANANHLASLFLGIELISLPLFGLVGYAFRQKRSLEASIKYT
                     ILSAAASSFLLFGMALVYAQSGDLSFVALGKNLGDGMLNEPLLLAGFGLMIVGLGFKL
                     SLVPFHLWTPDVYQGAPAPVSTFLATASKIAIFGVVMRLFLYAPVGDSEAIRVVLAII
                     AFASIIFGNLMALSQTNIKRLLGYSSISHLGYLLVALIALQTGEMSMEAVGVYLAGYL
                     FSSLGAFGVVSLMSSPYRGPDADSLFSYRGLFWHRPILAAVMTVMMLSLAGIPMTLGF
                     IGKFYVLAVGVQAHLWWLVGAVVVGSAIGLYYYLRVAVSLYLHAPEQPGRDAPSNWQY
                     SAGGIVVLISALLVLVLGIWPQPLISIVRLAMPLM"
     gene            complement(3096..4625)
                     /gene="nuoM"
                     /locus_tag="IRB70_000984"
     CDS             complement(3096..4625)
                     /gene="nuoM"
                     /locus_tag="IRB70_000984"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit M"
                     /protein_id="HBC0630931.1"
                     /translation="MLLPWLILIPFIGGFLCWQTERFGVKVPRWIALITMGLTLALSL
                     QLWLQGGYSLTQSAGIPQWQSEFEMPWIPRFGISIHLAIDGLSLLMVVLTGLLGVLAV
                     LCSWKEIEKYQGFFHLNLMWILGGVIGVFLAIDMFLFFFFWEMMLVPMYFLIALWGHK
                     ASDGKTRITAATKFFIYTQASGLVMLIAILALVFVHYNATGVWTFNYEELLNTPMSSG
                     VEYLLMLGFFIAFAVKMPVVPLHGWLPDAHSQAPTAGSVDLAGILLKTAAYGLLRFSL
                     PLFPNASAEFAPIAMWLGVIGIFYGAWMAFAQTDIKRLIAYTSVSHMGFVLIAIYTGS
                     QLAYQGAVIQMIAHGLSAAGLFILCGQLYERIHTRDMRMMGGLWSKMKWLPALSLFFA
                     VATLGMPGTGNFVGEFMILFGSFQVVPVITVISTFGLVFASVYSLAMLHRAYFGKAKS
                     QIASQELPGMSLRELFMILLLVVLLVLLGFYPQPILDTSHSAIGNIQQWFVNSVTTTR
                     P"
     gene            complement(4791..6632)
                     /gene="nuoL"
                     /locus_tag="IRB70_000985"
     CDS             complement(4791..6632)
                     /gene="nuoL"
                     /locus_tag="IRB70_000985"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit L"
                     /protein_id="HBC0630932.1"
                     /translation="MNMLALTIILPLIGFVLLAFSRGRWSENVSAIVGVGSVGLAALV
                     TAFIGVDFFANGEQAYSQPLWTWMSVGDFNIGFNLVLDGLSLTMLSVVTGVGFLIHMY
                     ASWYMRGEEGYSRFFAYTNLFIASMVVLVLADNLLLMYLGWEGVGLCSYLLIGFYYTD
                     PKNGAAAMKAFVVTRVGDVFLAFALFILYNELGTLNFREMVELAPAHFADGNNMLMWA
                     TLMLLGGAVGKSAQLPLQTWLADAMAGPTPVSALIHAATMVTAGVYLIARTHGLFLMT
                     PEVLHLVGIVGAVTLLLAGFAALVQTDIKRVLAYSTMSQIGYMFLALGVQAWDAAIFH
                     LMTHAFFKALLFLASGSVILACHHEQNIFKMGGLRKSIPLVYLCFLVGGAALSALPLV
                     TAGFFSKDEILAGAMANGHINLMVAGLVGAFMTSLYTFRMIFIVFHGKEQIHAHAVKG
                     VTHSLPLIVLLILSTFVGALIVPPLQGVLPQTTELAHGSMLTLEITSGVVAVVGILLA
                     AWLWLGKRTLVTSIANSAPGRLLGTWWYNAWGFDWLYDKVFVKPFLGIAWLLKRDPLN
                     SMMNIPAVLSRFAGKGLLLSENGYLRWYVASMSIGAVVVLALLMVLR"
     gene            complement(6629..6931)
                     /gene="nuoK"
                     /locus_tag="IRB70_000986"
     CDS             complement(6629..6931)
                     /gene="nuoK"
                     /locus_tag="IRB70_000986"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoK"
                     /protein_id="HBC0630933.1"
                     /translation="MIPLQHGLILAAILFVLGLTGLVIRRNLLFMLIGLEIMINASAL
                     AFVVAGSYWGQTDGQVMYILAISLAAAEASIGLALLLQLHRRRQNLNIDSVSEMRG"
     gene            complement(6928..7482)
                     /gene="nuoJ"
                     /locus_tag="IRB70_000987"
     CDS             complement(6928..7482)
                     /gene="nuoJ"
                     /locus_tag="IRB70_000987"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit J"
                     /protein_id="HBC0630934.1"
                     /translation="MEFAFYICGLIAILATLRVITHTNPVHALLYLIISLLAISGVFF
                     SLGAYFAGALEIIVYAGAIMVLFVFVVMMLNLGGSEIEQERQWLKPQVWIGPAILSAI
                     MLVVIVYAILGVNDQGIDGTPISAKAVGITLFGPYVLAVELASMLLLAGLVVAFHVGR
                     EERAGEVLSNRKDDSAKRKTEEHA"
     gene            complement(7494..8036)
                     /gene="nuoI"
                     /locus_tag="IRB70_000988"
     CDS             complement(7494..8036)
                     /gene="nuoI"
                     /locus_tag="IRB70_000988"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015959823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoI"
                     /protein_id="HBC0630935.1"
                     /translation="MTLKELLVGFGTQVRSIWMIGLHAFAKRETRMYPEEPVYLPPRY
                     RGRIVLTRDPDGEERCVACNLCAVACPVGCISLQKAETKDGRWYPEFFRINFSRCIFC
                     GLCEEACPTTAIQLTPDFEMGEYKRQDLVYEKEDLLISGPGKYPEYNFYRMAGMAIDG
                     KDKGEAENEAKPIDVKSLLP"
     gene            complement(8051..9028)
                     /gene="nuoH"
                     /locus_tag="IRB70_000989"
     CDS             complement(8051..9028)
                     /gene="nuoH"
                     /locus_tag="IRB70_000989"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015875065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoH"
                     /protein_id="HBC0630936.1"
                     /translation="MSWITPELIEILLTILKAVVILLVVVTCGAFMSFGERRLLGLFQ
                     NRYGPNRVGWGGSLQLVADMIKMFFKEDWIPKFSDRVIFTLAPMIAFTSLLLAFAIVP
                     VSPGWVVADLNIGILFFLMMAGLAVYAVLFAGWSSNNKYSLLGAMRASAQTLSYEVFL
                     GLSLMGVVAQAGSFNMTDIVNSQAHVWNVIPQFFGFITFAIAGVAVCHRHPFDQPEAE
                     QELADGYHIEYSGMKFGLFFVGEYIGIVTISALMVTLFFGGWQGPLLPPFIWFALKTA
                     FFMMMFILIRASLPRPRYDQVMSFGWKICLPLTLINLLVTAAVILWQAQ"
     gene            complement(9025..11751)
                     /gene="nuoG"
                     /locus_tag="IRB70_000990"
     CDS             complement(9025..11751)
                     /gene="nuoG"
                     /locus_tag="IRB70_000990"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311194.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoG"
                     /protein_id="HBC0630937.1"
                     /translation="MATIHVDGKEYEVNGADNLLEACLSLGLDIPYFCWHPALGSVGA
                     CRQCAVKQYQNAEDTRGRLVMSCMTPASDGTFISIDDEEAKQFRESVVEWLMTNHPHD
                     CPVCEEGGNCHLQDMTVMTGHSFRRYRFTKRTHRNQDLGPFISHEMNRCIACYRCVRY
                     YKDYADGTDLGVYGAHDNVYFGRPEDGTLESEFSGNLVEICPTGVFTDKTHSERYNRK
                     WDMQFAPSICQQCSIGCNISPGERYGELRRIENRYNGTVNHYFLCDRGRFGYGYVNLK
                     DRPRQPVQRRGNDFITLNAEQAMQGAADILRQSKKVIGIGSPRASVESNFALRELVGE
                     ENFYTGIAHGEQERLQLALKVLREGGIYTPALREIESYDAVLVLGEDVTQTGARVALA
                     VRQAVKGKAREMAAAQKVADWQIAAILNIGQRAKHPLFVTNVDDTRLDDIAAWTYRAP
                     VEDQARLGFAIAHALDNSAPAVDGIEPELQSKIDVIVQALAGAKKPLIISGTNAGSAE
                     VIQAAANVAKALKGRGADVGITMIARSVNSMGLGIMGGGSLEEALTELETGRADAVVV
                     LENDLHRHASATRVNAALAKAPLVMVVDHQRTAIMENAHLVLSAASFAESDGTVINNE
                     GRAQRFFQVYDPAYYDSKTVMLESWRWLHSLHSTLLSREVDWTQLDHVIDAVVAKIPE
                     LAGIKDAAPDATFRIRGQKLAREPHRYSGRTAMRANISVHEPRQPQDIDTMFTFSMEG
                     NNQPTAHRSQVPFAWAPGWNSPQAWNKFQDEVGGKLRFGDPGVRLFETSENGLDYFTS
                     VPARFQPQDGKWRIAPYYHLFGSDELSQRAPVFQSRMPQPYIKLNPADAAKLGVNAGT
                     RVSFSYDGNTVTLPVEIAEGLTAGQVGLPMGMSGIAPVLAGAHLEDLKEAQQ"
     gene            complement(11804..13141)
                     /gene="nuoF"
                     /locus_tag="IRB70_000991"
     CDS             complement(11804..13141)
                     /gene="nuoF"
                     /locus_tag="IRB70_000991"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoF"
                     /protein_id="HBC0630938.1"
                     /translation="MKNIIRTPETHPLTWRLRDDKQPVWLDEYRSKNGYEGARKALTG
                     LSPDEIVNQVKDSGLKGRGGAGFSTGLKWSLMPKDESMNIRYLLCNADEMEPGTYKDR
                     LLMEQLPHLLVEGMLISAFALKAYRGYIFLRGEYIEAAVNLRRAIAEATEAGLLGKNI
                     MGTGFDFELFVHTGAGRYICGEETALINSLEGRRANPRSKPPFPATSGAWGKPTCVNN
                     VETLCNVPAILANGVEWYQNISKSKDAGTKLMGFSGRVKNPGLWELPFGTTAREILED
                     YAGGMRDGLKFKAWQPGGAGTDFLTEAHLDLPMEFESIGKAGSRLGTALAMAVDHEIN
                     MVSLVRNLEEFFARESCGWCTPCRDGLPWSVKILRALERGEGQPGDIETLEQLCRFLG
                     PGKTFCAHAPGAVEPLQSAIKYFREEFEAGIKQPFSNTHLINGIQPNLLKERW"
     gene            complement(13138..13638)
                     /gene="nuoE"
                     /locus_tag="IRB70_000992"
     CDS             complement(13138..13638)
                     /gene="nuoE"
                     /locus_tag="IRB70_000992"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoE"
                     /protein_id="HBC0630939.1"
                     /translation="MHENQQPQTEAFELSAAEREAIEHEMHHYEDPRAASIEALKIVQ
                     KQRGWVPDGAIHAIADVLGIPASDVEGVATFYSQIFRQPVGRHVIRYCDSVVCHINGY
                     QGIQAALEKKLNIKPGQTTFDGRFTLLPTCCLGNCDKGPNMMIDEDTHAHLTPEAIPE
                     LLERYK"
     gene            complement(13641..15443)
                     /gene="nuoC"
                     /locus_tag="IRB70_000993"
     CDS             complement(13641..15443)
                     /gene="nuoC"
                     /locus_tag="IRB70_000993"
                     /EC_number="1.6.5.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit C/D"
                     /protein_id="HBC0630940.1"
                     /translation="MVNNMTDLTAQEPAWQTRDHLDDPVIGELRNRFGPDAFTVQATR
                     TGVPVVWIKREQLLEVGDFLKKLPKPYVMLFDLHGMDERLRTHREGLPAADFSVFYHL
                     ISIDRNRDIMLKVALAENDLHVPTFTKLFPNANWYERETWDLFGITFDGHPNLRRIMM
                     PQTWKGHPLRKDYPARATEFSPFELTKAKQDLEMEALTFKPEEWGMKRGTENEDFMFL
                     NLGPNHPSAHGAFRIVLQLDGEEIVDCVPDIGYHHRGAEKMGERQSWHSYIPYTDRIE
                     YLGGCVNEMPYVLAVEKLAGITVPDRVNVIRVMLSELFRINSHLLYISTFIQDVGAMT
                     PVFFAFTDRQKIYDLVEAITGFRMHPAWFRIGGVAHDLPRGWDRLLREFLDWMPKRLA
                     SYEKAALQNTILKGRSQGVAAYGAKEALEWGTTGAGLRATGIDFDVRKARPYSGYENF
                     DFEIPVGGGVSDCYTRVMLKVEELRQSLRILEQCLNNMPEGPFKADHPLTTPPPKERT
                     LQHIETLITHFLQVSWGPVMPANESFQMIEATKGINSYYLTSDGSTMSYRTRIRTPSY
                     AHLQQIPAAIRGSLVSDLIVYLGSIDFVMSDVDR"
     gene            complement(15537..16199)
                     /gene="nuoB"
                     /locus_tag="IRB70_000994"
     CDS             complement(15537..16199)
                     /gene="nuoB"
                     /locus_tag="IRB70_000994"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoB"
                     /protein_id="HBC0630941.1"
                     /translation="MDYTLTRIDPNGENDRYPLQKQEIVTDPLEQEVNKNVFMGKLND
                     MVNWGRKNSIWPYNFGLSCCYVEMVTSFTAVHDVARFGAEVLRASPRQADLMVVAGTC
                     FTKMAPVIQRLYDQMLEPKWVISMGACANSGGMYDIYSVVQGVDKFIPVDVYIPGCPP
                     RPEAYMQALMLLQESIGKERRPLSWVVGDQGVYRANMQSERERKRGERIAVTNLRTPD
                     EI"
     gene            complement(16215..16658)
                     /gene="nuoA"
                     /locus_tag="IRB70_000995"
     CDS             complement(16215..16658)
                     /gene="nuoA"
                     /locus_tag="IRB70_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-quinone oxidoreductase subunit NuoA"
                     /protein_id="HBC0630942.1"
                     /translation="MSMSTSTEVIAHHWAFAIFLIVAIGLCCLMLVGGWFLGGRARAR
                     SKNVPFESGIDSVGSARLRLSAKFYLVAMFFVIFDVEALYLFAWSTSIRESGWVGFVE
                     AAIFIFVLLAGLVYLVRIGALDWTPARSRRERMNPETNSIANRQR"
     gene            complement(17288..18226)
                     /gene="lrhA"
                     /locus_tag="IRB70_000996"
     CDS             complement(17288..18226)
                     /gene="lrhA"
                     /locus_tag="IRB70_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LrhA"
                     /protein_id="HBC0630943.1"
                     /translation="MISANRPIINLDLDLLRTFVAVADLNTFAAAAAAVCRTQSAVSQ
                     QMQRLEQLVGKELFARHGRNKLLTEHGIQLLGYARKILRFNDEACSSLMFSNLQGVLT
                     IGASDESADTILPFLLNRVSSVYPKLALDVRVKRNAYMAEMLESQEVDLMVTTHRPST
                     FKALNLRTSPTHWYCAAEYVLQKGEPIPLVLLDDPSPFRDMVLATLNKADIPWRLAYV
                     ASTLPAVRAAVKAGLGVTARPVEMMSPDLRVLSGVDGLPPLPDTEYLLCYDPSSNNEL
                     AQVIYQAMESYHNPWQYSPMSAPEGDDSLLIERDIE"
     gene            19146..20363
                     /gene="alaA"
                     /locus_tag="IRB70_000997"
     CDS             19146..20363
                     /gene="alaA"
                     /locus_tag="IRB70_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase AlaA"
                     /protein_id="HBC0630944.1"
                     /translation="MSPIEKSSKLENVCYDIRGPVLKEAKRLEEEGNKVLKLNIGNPA
                     PFGFDAPDEILVDVIRNLPTAQGYCDSKGLYSARKAIMQHYQARGMRDVTVEDIYIGN
                     GVSELIVQAMQALLNSGDEMLVPAPDYPLWTAAVSLSSGKAVHYLCDESSDWFPDLDD
                     IRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQHNLIIFADEIYDKILYDDA
                     EHHSIAPLAPDLLTITFNGLSKTYRVAGFRQGWMVLNGPKKHAKGYIEGLEMLASMRL
                     CANVPAQHAIQTALGGYQSISEFITPGGRLYEQRNRAWELINDIPGVSCVKPRGALYM
                     FPKIDARRFNIHDDQKMVLDFLLQEKVLLVQGTAFNWPWPDHFRIVTLPRVDDIELSL
                     SKFARFLSGYHQL"
     gene            20447..21046
                     /gene="yfbR"
                     /locus_tag="IRB70_000998"
     CDS             20447..21046
                     /gene="yfbR"
                     /locus_tag="IRB70_000998"
                     /EC_number="3.1.3.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-deoxynucleotidase"
                     /protein_id="HBC0630945.1"
                     /translation="MKQSHFFAHLSRLKLINRWPLMRNVRTENVSEHSLQVAMVAHAL
                     AAIKNRKFGGNVNAERIALLAMYHDASEVLTGDLPTPVKYFNAQIAQEYKAIEKIAQQ
                     KLVDMVPEELRDIFAPLIDEHAYSDEEKSLVKQADALCAYLKCLEELAAGNNEFLLAK
                     TRLEATLEARRSQEMDYFMEVFVPSFHLSLDEISQDSPL"
     gene            complement(21105..22937)
                     /locus_tag="IRB70_000999"
     CDS             complement(21105..22937)
                     /locus_tag="IRB70_000999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SLC13 family permease"
                     /protein_id="HBC0630946.1"
                     /translation="MNGELIWVLSLLAVAIVLFATGRVRMDAVALFVIVAFALSGTLT
                     VPEVFSGFSDPNVVLIAALFIIGDGLVRTGVATVMGTWLVKVAGNSEIKMLVLLMLTV
                     AGLGAFMSSTGVVAIFIPVVLSVAMRMQTSPSRLMMPLSFAGLISGMMTLVATPPNLV
                     VNSELLREGYHGFSFFSVTPIGLVVLVLGILYMLVMRFMLKGDTQTPQREGWTRRTFR
                     DLIREYRLTGRARRLAIRPGSPMIGQRLDDLKLRERYGANVIGVERWRRFRRVIVNVN
                     GVSEFRARDVLLIDMSAADVDLRQFCSEQLLEPMVLRGEYFSDQALDVGMAEISLIPE
                     SELIGKSVREIGFRTRYGLNVVGLKRNGEAMEGSLADEPLLLGDIILVVGNWKLIGML
                     AKQGRDFVALNLPEEVSEASPAHSQAPHAIFCLVLMVALMLTDEIPNPVAAIIACLLM
                     GKFRCIDAESAYKSIHWPSIILIVGMMPFAVALQKTGGVALAVKGLMDIGGGYGPHMM
                     LGCLFVLSAVIGLFISNTATAVLMAPIALAAAKTMGVSPYPFAMVVAMAASAAFMTPV
                     SSPVNTLVLGPGNYSFSDFVKLGVPFTIIVMAVCVVMIPMLFPF"
     gene            complement(23024..23674)
                     /gene="hxpA"
                     /locus_tag="IRB70_001000"
     CDS             complement(23024..23674)
                     /gene="hxpA"
                     /locus_tag="IRB70_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpA"
                     /protein_id="HBC0630947.1"
                     /translation="MRCKGFLFDLDGTLVDSLPAVERAWSNWARRHGLAPEEVLAFIH
                     GKQAITSLRHFMAGKSEADIAAEFTRLEQIEATETEGITALPGAIALLNHLNKAGIPW
                     AIVTSGSMPVARARHKIAGLPAPEVFVTAERVKRGKPEPDAYLLGAQLLGLAPQECVV
                     VEDAPAGVLSGLAAGCHVIAVNAPADTPRLNEVDLVLHSLEQITVTKQPNGDVIIQ"
     gene            complement(23685..24179)
                     /locus_tag="IRB70_001001"
     CDS             complement(23685..24179)
                     /locus_tag="IRB70_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007371080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfbU family protein"
                     /protein_id="HBC0630948.1"
                     /translation="MEMTNAQRLILSNQYKMMTMLDPANAERYRRLQTIIERGYGLQM
                     RELDREFGELKEETCRTIIDIMEMYHALHVSWSNLQDQQSIDERRVTFLGFDAATEAR
                     YLGYVRFMVNVEGRYTHFDAGTHGFNAQTPMWEKYQRMLNVWHACPRQYHLSANEINQ
                     IINA"
     gene            complement(24263..24718)
                     /locus_tag="IRB70_001002"
     CDS             complement(24263..24718)
                     /locus_tag="IRB70_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF412 domain-containing protein"
                     /protein_id="HBC0630949.1"
                     /translation="MSTPDNRSVNFFSLFRRGQHYSKTWPLEKRLAPVFVENRVIKMT
                     RYAIRFMPPIAVFTLCWQIALGGQLGPAVATALFALSLPMQGLWWLGKRSVTPLPPAI
                     LNWFYEVRGKLQESGQVLAPVEGKPDYQALADTLKRAFKQLDKTFLDDL"
     gene            25056..26258
                     /gene="ackA"
                     /locus_tag="IRB70_001003"
     CDS             25056..26258
                     /gene="ackA"
                     /locus_tag="IRB70_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBC0630950.1"
                     /translation="MSSKLVLVLNCGSSSLKFAIIDAVNGEEYLSGLAECFHLPEARI
                     KWKMDGNKQEAALGAGAAHSEALNFIVNTILAQKPELSAQLTAIGHRIVHGGEKYTSS
                     VVIDESVIQGIKDAASFAPLHNPAHLIGIEEALKSFPQLKDKNVAVFDTAFHQTMPEE
                     SYLYALPYNLYKEHGIRRYGAHGTSHFYVTQEAAKMLNKPVEELNIITCHLGNGGSVS
                     AIRNGKCVDTSMGLTPLEGLVMGTRSGDIDPAIIFHLHDTLGMSVDAINKLLTKESGL
                     LGLTEVTSDCRYVEDNYATKEDAKRAMDVYCHRLAKYIGAYTALMDGRLDAVVFTGGI
                     GENAAMVRELSLGKLGVLGFEVDHERNLAARFGKSGFINKEGTRPAVVIPTNEELVIA
                     QDASRLTA"
     gene            26333..28477
                     /gene="pta"
                     /locus_tag="IRB70_001004"
     CDS             26333..28477
                     /gene="pta"
                     /locus_tag="IRB70_001004"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBC0630951.1"
                     /translation="MSRIIMLIPTGTSVGLTSVSLGVIRAMERKGVRLSVFKPIAQPR
                     TGGDAPDQTTTIVRANSSTTTAAEPLKMSYVEGLLSSNQKDVLMEEIVANYHANTKDA
                     EVVLVEGLVPTRKHQFAQSLNYEIAKTLNAEIVFVMSQGTDTPEQLKERIELTRNSFG
                     GAKNTNITGVIVNKLNAPVDEQGRTRPDLSEIFDDSTKAKVNNVDPAKLQESSPLPVL
                     GAVPWSFDLIATRAIDMARHLNATIINEGDINTRRVKSVTFCARSIPHMLEHFRAGSL
                     LVTSADRPDVLVAACLAAMNGVEIGALLLTGGYEMDARISKLCERAFATGLPVFMVNT
                     NTWQTSLSLQSFNLEVPVDDHERIEKVQEYVANYINADWIDSLTATSERSRRLSPPAF
                     RYQLTELARKAGKRIVLPEGDEPRTVKAAAICAERGIATCVLLGNPAEINRVAASQGV
                     ELGAGIEIVDPEVVRENYVGRLVELRKNKGMTETVAREQLEDNVVLGTLMLEQDEVDG
                     LVSGAVHTTANTIRPPLQLIKTAPGSSLVSSVFFMLLPEQVYVYGDCAINPDPTAEQL
                     AEIAIQSADSAAAFGIEPRVAMLSYSTGTSGAGSDVEKVREATRLAQEKRPDLMIDGP
                     LQYDAAVMADVAKSKAPNSPVAGRATVFIFPDLNTGNTTYKAVQRSADLISIGPMLQG
                     MRKPVNDLSRGALVDDIVYTIALTAIQSAQQQ"
     gene            28667..30187
                     /gene="yfcC"
                     /locus_tag="IRB70_001005"
     CDS             28667..30187
                     /gene="yfcC"
                     /locus_tag="IRB70_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBC0630952.1"
                     /translation="MSAITESKPTRRWAMPDTLVIIFFVAILTSLATWVVPVGMFDSQ
                     EVQYQVDGQTKTRKVVDPHSFRILTNEAGEPEYHRVQLFTTGDERPGLMNFPFEGLTS
                     GSKYGTAVGIIMFMLVIGGAFGIVMRTGTIDNGILALIRHTRGNEILFIPALFILFSL
                     GGAVFGMGEEAVAFAIIIAPLMVRLGYDSITTVLVTYIATQIGFASSWMNPFCVVVAQ
                     GIAGVPVLSGSGLRIVVWVIATLIGLIFTMVYASRVKKNPLLSCVHESDRFFREKQAD
                     VEQRPFTFGDWLVLIVLTAVMVWVIWGVIVNAWFIPEIASQFFTMGLVIGIIGVVFRL
                     NGMTVNTMASSFTEGARMMIAPALLVGFAKGILLLVGNGEAGDASVLNTILNSIANAI
                     SGLDNAVAAWFMLLFQAVFNFFVTSGSGQAALTMPLLAPLGDLVGVNRQVTVLAFQFG
                     DGFSHIIYPTSASLMATLGVCRVDFRNWLKVGATLLGLLFIMSSVVVIGAQLMGYH"
     gene            complement(30221..30763)
                     /gene="yfcD"
                     /locus_tag="IRB70_001006"
     CDS             complement(30221..30763)
                     /gene="yfcD"
                     /locus_tag="IRB70_001006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase YfcD"
                     /protein_id="HBC0630953.1"
                     /translation="MEQRRLASTEWVDIVNEENEVIAQASREQMRAQCLRHRATYIVV
                     HDGMGKILVQRRTETKDFLPGMLDATAGGVVQADEQLLESARREAEEELGIAGVPFAE
                     HGQFYFEDKNCRVWGALFSCVSHGPFALQEDEVSEVCWLTPEEITARCDEFTPDSLKA
                     LALWMKRNAKNEAVETETAE"
     gene            complement(30821..31372)
                     /gene="yfcE"
                     /locus_tag="IRB70_001007"
     CDS             complement(30821..31372)
                     /gene="yfcE"
                     /locus_tag="IRB70_001007"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311211.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBC0630954.1"
                     /translation="MKLMFASDIHGSLPATERVLELFAQSGAQWLVILGDVLNHGPRN
                     ALPEGYAPAKVAERLNEVAHKVIAVRGNCDSEVDQMLLHFPITAPWQQVLLEKQRLFL
                     THGHLFGPENLPALNQNDVLVYGHTHLPVAEQRGEIFHFNPGSVSIPKGGNPASYGML
                     DNDVLSVIALNDQSIIAQVAINP"
     gene            complement(31428..32072)
                     /gene="yfcF"
                     /locus_tag="IRB70_001008"
     CDS             complement(31428..32072)
                     /gene="yfcF"
                     /locus_tag="IRB70_001008"
                     /EC_number="2.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione transferase"
                     /protein_id="HBC0630955.1"
                     /translation="MSKPAITLWSDAHFFSPYVLSAWVALQEKGLSFHIKTIDLDSGE
                     HLQPTWQGYGQTRRVPLLQIDDFELSESSAIAEYLEDRFAPPTWERIYPLDLENRARA
                     RQIQAWLRSDLMPIREERPTDVVFAGAKKAPLTAEGKASAEKLFAMAEHLLALGRPNL
                     FGEWCIADTDLALMINRLVLHGDEVPERLVDYATFQWQRASVQRFIALSAKQSG"
     gene            32208..32855
                     /gene="yfcG"
                     /locus_tag="IRB70_001009"
     CDS             32208..32855
                     /gene="yfcG"
                     /locus_tag="IRB70_001009"
                     /EC_number="1.8.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GSH-dependent disulfide bond oxidoreductase"
                     /protein_id="HBC0630956.1"
                     /translation="MIDLYFAPTPNGHKITLFLEEAGLDYRLIKVDLGKGGQFRPEFL
                     RISPNNKIPAIVDHSPADGGEPLSLFESGAILLYLAEKTGLFLSHETRERAATLQWLF
                     WQVGGLGPMLGQNHHFNHAAPQTIPYAIERYQVETQRLYHVLNKRLENSPWLGGENYS
                     IADIACWPWVNAWTRQRIDLAMYPAVKNWHERIRSRPATGQALLKAQHGDDRSDS"
     gene            32912..33274
                     /gene="folX"
                     /locus_tag="IRB70_001010"
     CDS             32912..33274
                     /gene="folX"
                     /locus_tag="IRB70_001010"
                     /EC_number="5.1.99.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate 2'-epimerase"
                     /protein_id="HBC0630957.1"
                     /translation="MAQPAAIIRIKNLRLRTFIGIKEEEINNRQDIVINVTIHYPADK
                     ARTSEDINDALNYRTVTKNIIQHVENNRFSLLEKLTQDVLDIAREHHWVTYAEVEIDK
                     LHALRYADSVSMTLSWQR"
     gene            33295..34188
                     /locus_tag="IRB70_001011"
     CDS             33295..34188
                     /locus_tag="IRB70_001011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01777 family oxidoreductase"
                     /protein_id="HBC0630958.1"
                     /translation="MKIVITGGTGLIGRHLIPRLLDLGHQITVVTRNPQKASSVLGPR
                     VTLWQGLADQSNLNGVDAVINLAGEPIADKRWTHEQKERLCQSRWNITQKLVDLINAS
                     DTPPSVLISGSATGYYGDLGEVVVTEEEPPHNEFTHKLCARWEEIACRAQSDKTRVCL
                     LRTGVVLAPDGGILGKMLPPFRLGLGGPIGSGRQYLAWIHIDDMVNGILWLLDNELRG
                     PFNMVSPYPVRNEQFAHALGHALHRPAILRVPATAIRLLMGESSVLVLGGQRALPKRL
                     EEAGFAFRWYDLEEALADVVR"
     gene            complement(34236..35126)
                     /gene="rpnB"
                     /locus_tag="IRB70_001012"
     CDS             complement(34236..35126)
                     /gene="rpnB"
                     /locus_tag="IRB70_001012"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnB"
                     /protein_id="HBC0630959.1"
                     /translation="MTISTTSTPHDAVFKSFLRHPDTARDFIDIHLPAPLRKLCDLTT
                     LKLEPNSFIDEDLRQYYSDLLWSVKTQEGAGYIYVVIEHQSKPEELMAFRMMRYSIAA
                     MQNHLDAGYKELPLVIPMLFYHGCRSPYPYSLCWLDEFAEPAIARKIYSSAFPLVDIT
                     VVPDDEIMQHRKMALLELIQKHIRQRDLLGLVDQIVSLLVTGNTNDRQLKALFNYVLQ
                     TGDAQRFRAFIGEIAERAPQEKEKLMTIADRLREEGAMQGKREEALRIAQEMLERGLD
                     RELVMMVTRLSPDDLIAQSH"
     gene            complement(35323..36096)
                     /gene="hisP"
                     /locus_tag="IRB70_001013"
     CDS             complement(35323..36096)
                     /gene="hisP"
                     /locus_tag="IRB70_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter ATP-binding protein
                     HisP"
                     /protein_id="HBC0630960.1"
                     /translation="MSENKLNVIDLHKRYGEHEVLKGVSLQANAGDVISIIGSSGSGK
                     STFLRCINFLEKPSEGSIVVNGQTINLVRDKDGQLKVADKNQLRLLRTRLTMVFQHFN
                     LWSHMTVLENVMEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGKYPVHLSGGQQQR
                     VSIARALAMEPEVLLFDEPTSALDPELVGEVLRIMQQLAEEGKTMVVVTHEMGFARHV
                     STHVIFLHQGKIEEEGAPEQLFGNPQSPRLQQFLKGSLK"
     gene            complement(36104..36820)
                     /locus_tag="IRB70_001014"
     CDS             complement(36104..36820)
                     /locus_tag="IRB70_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0630961.1"
                     /translation="MIEILHEYWKPLLWTDGYRFTGVAITLWLLILSVVIGGVLALFL
                     AIGRVSSNKYIQFPIWLFTYIFRGTPLYVQLLVFYSGMYTLEIVKGTEFLNAFFRSGL
                     NCTVLALTLNTCAYTTEIFAGAIRSVPHGEIEAARAYGFSTFKMYRCIILPSALRIAL
                     PAYSNEVILMLHSTALAFTATVPDLLKIARDINAATYQPFTAFGIAAVLYLIISYVLI
                     SLFRRAEKRWLQHVKPSSTH"
     gene            complement(36817..37503)
                     /gene="hisQ"
                     /locus_tag="IRB70_001015"
     CDS             complement(36817..37503)
                     /gene="hisQ"
                     /locus_tag="IRB70_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012124147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter permease HisQ"
                     /protein_id="HBC0630962.1"
                     /translation="MLYGFSGVILQGALVTLELAISSVVLAVIIGLIGAGGKLSQNRL
                     SGLIFEGYTTLIRGVPDLVLMLLIFYGLQIALNTVTEAMGVGQIDIDPMVAGIITLGF
                     IYGAYFTETFRGAFMAVPKGHIEAATAFGFTRGQVFRRIMFPAMMRYALPGIGNNWQV
                     ILKSTALVSLLGLEDVVKATQLAGKSTWEPFYFAIVCGVIYLVFTTVSNGVLLFLERR
                     YSVGVKRADL"
     gene            complement(37593..38375)
                     /gene="hisJ"
                     /locus_tag="IRB70_001016"
     CDS             complement(37593..38375)
                     /gene="hisJ"
                     /locus_tag="IRB70_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine ABC transporter substrate-binding
                     protein HisJ"
                     /protein_id="HBC0630963.1"
                     /translation="MKKLVLSLSLVLAFSSATAAFAAIPQNIRIGTDPTYAPFESKNS
                     QGELVGFDIDLAKELCKRINTQCTFVENPLDALIPSLKAKKIDAIMSSLSITEKRQQE
                     IAFTDKLYAADSRLVVAKNSDIQPTVESLKGKRVGVLQGTTQETFGNEHWAPKGIEIV
                     SYQGQDNIYSDLTAGRIDAAFQDEVAASEGFLKQPVGKDYKFGGPSVKDEKLFGVGTG
                     MGLRKEDNELREALNKAFAEMRADGTYEKLAKKYFDFDVYGG"
     gene            complement(38596..39378)
                     /gene="argT"
                     /locus_tag="IRB70_001017"
     CDS             complement(38596..39378)
                     /gene="argT"
                     /locus_tag="IRB70_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine/arginine/ornithine ABC transporter
                     substrate-binding protein ArgT"
                     /protein_id="HBC0630964.1"
                     /translation="MKKSILALSLLVGLSAAASSYAALPETVRIGTDTTYAPFSSKDA
                     KGDFVGFDIDLGNEMCKRMQVKCTWVASDFDALIPSLKAKKIDAIISSLSITDKRQQE
                     IAFSDKLYAADSRLIAAKGSPIQPTLDSLKGKHVGVLQGSTQEAYANDNWRSKGVDVV
                     AYANQDLVYSDLAAGRLDAALQDEVAASEGFLKQPAGKDFAFAGPSVKDKKYFGDGTG
                     VGLRKDDAELTAAFNKALNELRQDGTYDKMAKKYFDFNVYGD"
     gene            complement(39644..40213)
                     /gene="ubiX"
                     /locus_tag="IRB70_001018"
     CDS             complement(39644..40213)
                     /gene="ubiX"
                     /locus_tag="IRB70_001018"
                     /EC_number="2.5.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin prenyltransferase UbiX"
                     /protein_id="HBC0630965.1"
                     /translation="MKRLIVGISGASGAIYGVRLLQVLRDVADVETHLVMSQAARQTL
                     SLETDFSLREVQALADVTHDARDIAASISSGSFQTLGMVILPCSIKTLSGIVHSYTDG
                     LLTRAADVVLKERRPLVLCVRETPLHLGHLRLMTQAAEIGAVIMPPVPAFYHRPQSLD
                     DVINQTVNRVLDQFAITLPEDLFARWQGA"
     gene            complement(40308..41825)
                     /gene="purF"
                     /locus_tag="IRB70_001019"
     CDS             complement(40308..41825)
                     /gene="purF"
                     /locus_tag="IRB70_001019"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820991.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBC0630966.1"
                     /translation="MCGIVGIAGVMPVNQSIYDALTVLQHRGQDAAGIITIDANNCFR
                     LRKANGLVSDVFEARHMQRLQGNMGIGHVRYPTAGSSSASEAQPFYVNSPYGITLAHN
                     GNLTNAHELRKKLFEEKRRHINTTSDSEILLNIFASELDNFRHYPLEADNIFAAIAAT
                     NRLIRGAYACVAMIIGHGMVAFRDPNGIRPLVLGKRDIDENRTEYMVASESVALDTLG
                     FDFLRDVAPGEAIYITEEGQLFTRQCADNPVSNPCLFEYVYFARPDSFIDKISVYSAR
                     VNMGTKLGEKIAREWEDLDIDVVIPIPETSCDIALEIARILGKPYRQGFVKNRYVGRT
                     FIMPGQQLRRKSVRRKLNANRAEFRDKNVLLVDDSIVRGTTSEQIIEMAREAGAKKVY
                     LASAAPEIRFPNVYGIDMPSATELIAHGREVDEIRQIIGADGLIFQDLNDLIEAVRAE
                     NPDIQQFECSVFNGVYVTKDVDQGYLDFLDTLRNDDAKAVQRQNEVENLEMHNEG"
     gene            complement(41862..42350)
                     /gene="cvpA"
                     /locus_tag="IRB70_001020"
     CDS             complement(41862..42350)
                     /gene="cvpA"
                     /locus_tag="IRB70_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin V production protein"
                     /protein_id="HBC0630967.1"
                     /translation="MVWIDYAIIAVIAFSSLVSLIRGFVREALSLVTWGCAFFVASHY
                     YTYLSVWFTGFEDELVRNGIAIAVLFIATLIVGAIVNFVIGQLVEKTGLSGTDRVLGV
                     CFGALRGVLIVAAILFFLDSFTGVSKSEDWSKSQLIPQFSFIIRWFFDYLQSSSSFLP
                     RA"
     gene            complement(42586..43236)
                     /gene="dedD"
                     /locus_tag="IRB70_001021"
     CDS             complement(42586..43236)
                     /gene="dedD"
                     /locus_tag="IRB70_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416817.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DedD"
                     /protein_id="HBC0630968.1"
                     /translation="MASKFQNRLVGTIVLVALGVIVLPGLLDGQKKHYQDEFAAIPLV
                     PKAGDRDEPDMMPAATQALPTQPPEGAAEEVRAGDAAAPSLDPATIAANNTEFEPEPA
                     PVAPPKPKPVEPPKPKVEAPPAPKPVVEEKAAPTGKAYVVQLGALKNADKVNEIVGKL
                     RGAGYRVYTSPSTPVQGKITRILVGPDASKDKLKGSLGELKQLSGLSGVVMGYTPN"
     gene            complement(43226..44494)
                     /gene="folC"
                     /locus_tag="IRB70_001022"
     CDS             complement(43226..44494)
                     /gene="folC"
                     /locus_tag="IRB70_001022"
                     /EC_number="6.3.2.12"
                     /EC_number="6.3.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tetrahydrofolate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBC0630969.1"
                     /translation="MIIKRTPQAASPLASWLSYLENLHSKTIDLGLERVSQVAARLGV
                     LKPAPFVFTVAGTNGKGTTCRTLESILMAAGYNVGVYSSPHLVRYTERVRVQGQELPE
                     SAHTASFAEIESARGDISLTYFEYGTLSALWLFKQAQLDVVILEVGLGGRLDATNIVD
                     ADVAVVTSIALDHTDWLGPDRESIGREKAGIFRSEKPAIVGEPEMPSTIADVAQEKGA
                     LLQRRGVEWNYSVTDHDWTFSDAHGTLENLPLPLVPQPNAATALAALRASGLEVSENA
                     IRDGIASAILPGRFQIVSESPRVIFDVAHNPHAAEYLTGRMKALPKNGRVLAVIGMLH
                     DKDIAGTLAWLKSVVDDWYCAPLEGPRGATAEQLLEHLGNGKSFDSVAQAWDAAMADA
                     KAEDTVLVCGSFHTVAHVMEVIDARRSGGK"
     gene            complement(44564..45478)
                     /gene="accD"
                     /locus_tag="IRB70_001023"
     CDS             complement(44564..45478)
                     /gene="accD"
                     /locus_tag="IRB70_001023"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase, carboxyltransferase
                     subunit beta"
                     /protein_id="HBC0630970.1"
                     /translation="MSWIERIKSNITPTRKASIPEGVWTKCDSCGQVLYRAELERNLE
                     VCPKCDHHMRMTARNRLHSLLDEGSLVELGSELEPKDVLKFRDSKKYKDRLASAQKET
                     GEKDALVVMKGTLYGMPVVAAAFEFAFMGGSMGSVVGARFVRAVEQALEDNCPLICFS
                     ASGGARMQEALMSLMQMAKTSAALAKMQERGLPYISVLTDPTMGGVSASFAMLGDLNI
                     AEPKALIGFAGPRVIEQTVREKLPPGFQRSEFLIEKGAIDMIVRRPEMRLKLASILAK
                     LMNLPAPNPEAPREGVVVPPVPDQEPEA"
     gene            complement(45634..46293)
                     /locus_tag="IRB70_001024"
     CDS             complement(45634..46293)
                     /locus_tag="IRB70_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBC0630971.1"
                     /translation="MDLIYFLIDFILHIDVHLAELVAEYGVWVYAILFLILFCETGLV
                     VTPFLPGDSLLFVAGALASLETNDLNVHMMVVLMLIAAIVGDAVNYTIGRLFGDKLFS
                     NPDSKIFRRSYLDKTHQFYEKHGGKTIILARFVPIVRTFAPFVAGMGHMSYRHFAAFN
                     VIGALLWVLIFTYAGYFFGTLPFIQSNLKLMIVGIIFVSILPGVFEFIRHKRAAARAA
                     K"
     gene            complement(46376..47188)
                     /gene="truA"
                     /locus_tag="IRB70_001025"
     CDS             complement(46376..47188)
                     /gene="truA"
                     /locus_tag="IRB70_001025"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBC0630972.1"
                     /translation="MSDQQQPPVYKIALGIEYDGSKYYGWQRQNEVRSVQEKLEKALS
                     QVANEPITVFCAGRTDAGVHGTGQVVHFETTAQRKDAAWTLGVNANLPGDIAVRWVKA
                     VPDDFHARFSATARRYRYIIYNHRLRPAVLSKGVTHFYEPLDAERMHRAAQCLLGEND
                     FTSFRAVQCQSRTPWRNVMHINVTRHGPYVVVDIKANAFVHHMVRNIVGSLMEVGAHN
                     QPESWIAELLAAKDRTLAAATAKAEGLYLVAVDYPDRYDLPKPPMGPLFLAD"
     gene            complement(47188..48201)
                     /locus_tag="IRB70_001026"
     CDS             complement(47188..48201)
                     /locus_tag="IRB70_001026"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBC0630973.1"
                     /translation="MSEGWNIAVLGATGAVGEALLETLAERQFPVGEIYALARNESAG
                     EQLRFGGKTITVQDAAEFDWTQAQLAFFVAGKEATAAWVEEATNSGCLVIDSSGLFAL
                     EPDVPLVVPEVNPFVLTDYRNRNVIAVPDSLTSQLLAALKPLIDQGGLSRISVTSLIS
                     ASAQGKKAVDALAGQSAKLLNGIPIDEEDFFGRQLAFNMLPLLPDSEGSVREERRIVD
                     EVRKILQDEGLMISASVVQAPVFYGHAQMVNFEALRPLAAEEARDAFAQGEDIVLSEE
                     NEFPTQVGDASGTPHLSVGCVRNDYGMPEQVQFWSVADNVRFGGALMAVKIAEKLVQE
                     YLY"
     gene            complement(48267..49403)
                     /gene="pdxB"
                     /locus_tag="IRB70_001027"
     CDS             complement(48267..49403)
                     /gene="pdxB"
                     /locus_tag="IRB70_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-phosphoerythronate dehydrogenase PdxB"
                     /protein_id="HBC0630974.1"
                     /translation="MKILVDENMPYARDLFSRLGEVTAVPGRPIPVAQLADADALMVR
                     SVTKVNESLLAGKPIKFVGTATAGTDHVDEAWLKQAGIGFSAAPGCNAIAVVEYVFSS
                     LLMLAERDGFSLHERTVGIVGVGNVGRRLQARLEALGIKTLLCDPPRADRGDEGDFRS
                     LDELVQHADILTFHTPLFKDGPYKTRHLADEKLIRSLKPGAILINACRGAVVDNTALL
                     TCLNEGQKLSVVLDVWEGEPELNVELLTKVDIGTPHIAGYTLEGKARGTTQVFEAYSK
                     FIGHEQHVALDTLLPAPEFGRITLHGPLDQPTLKRLVHLVYDVRRDDAPLRKVAGIPG
                     EFDKLRKNYLERREWSSLYVICDDASAASLLCKLGFNAVHHPAR"
     gene            49502..50497
                     /gene="flk"
                     /locus_tag="IRB70_001028"
     CDS             49502..50497
                     /gene="flk"
                     /locus_tag="IRB70_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulator Flk"
                     /protein_id="HBC0630975.1"
                     /translation="MIQPISGPPPGQPPGQGDNLPSGAGNQPLSSQQRTSLESLMTKV
                     TSLTQQQRAELWAGIRHDIGLSGDSPLLSRHFPAAEHNLAQRLLAAQKSHSARQLLAQ
                     LGEYLRLGNNRQAVTDYIRHNFGQTPLNQLSPEQLKTILTLLQEGKMVIPQPQQREAT
                     DRPLLPAEHNALKQLVTKLAAATGEPSKQIWQSMLELSGVKDGELIPAKLFNHLVTWL
                     QARQTLSQQNTPTLESLQMALKQPLDASELAALSAYIQQKYGLSAQSSLSSSQAEDIL
                     NQLYQRRVKGIDPRDMQPLLNPFPPMMDTLQNMATRPALWILLVAIILMLVWLVR"
     gene            complement(50494..51672)
                     /locus_tag="IRB70_001029"
     CDS             complement(50494..51672)
                     /locus_tag="IRB70_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0630976.1"
                     /translation="MTAVSQTETRSSANFSLFRIAFAVFLTYMTVGLPLPVIPLFVHH
                     ELGYGNTMVGIAVGIQFLATVLTRGYAGRLADQYGAKRSALQGMLACGLAGGALLLAA
                     ILPVPAPFKFALLVVGRLILGFGESQLLTGALTWGLGIVGPKHSGKVMSWNGMAIYGA
                     LAVGAPLGLLIHSHYGFAALALTTMALPLLAWACNGTVRKVPALAGERPSLWSVVGLI
                     WKPGLGLALQGVGFAVIGTFVSLYFASKGWAMAGFTLTAFGGAFVVMRVMFGWMPDRF
                     GGVKVAIVSLLVETVGLLLLWQAPGAWVALAGAALTGAGCSLIFPALGVEVVKRVPSQ
                     VRGTALGGYAAFQDIALGVSGPLAGMLATTFGYSSVFLAGAISAVLGIIVTILSFRRG
                     "
     gene            complement(51904..53124)
                     /gene="fabB"
                     /locus_tag="IRB70_001030"
     CDS             complement(51904..53124)
                     /gene="fabB"
                     /locus_tag="IRB70_001030"
                     /EC_number="2.3.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase I"
                     /protein_id="HBC0630977.1"
                     /translation="MKRAVITGLGIVSSIGNNQQEVLASLREGRSGITFSQELKDSGM
                     RSHVWGNVKLDTTGLIDRKVVRFMSDASIYAFLSMEQAIADAGLSPEAYQNNPRVGLI
                     AGSGGGSPRFQVFGADAMRGPRGLKAVGPYVVTKAMASGVSACLATPFKIHGVNYSIS
                     SACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDAMGALSTKYNDTPEKA
                     SRTYDAHRDGFVIAGGGGMVVVEELEHALARGAHIYAEIVGYGATSDGADMVAPSGEG
                     AVRCMKMAMHGVDTPIDYLNSHGTSTPVGDVKELAAIREVFGDKSPAISATKAMTGHS
                     LGAAGVQEAIYSLLMLEHGFIAPSINIEELDEQAAGLNIVTETTDRELTTVMSNSFGF
                     GGTNATLVMRKLKD"
     gene            53283..55289
                     /gene="mnmC"
                     /locus_tag="IRB70_001031"
     CDS             53283..55289
                     /gene="mnmC"
                     /locus_tag="IRB70_001031"
                     /EC_number="1.5.-.-"
                     /EC_number="2.1.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416827.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA
                     (5-methylaminomethyl-2-thiouridine)(34)-methyltransferase
                     MnmD/FAD-dependent
                     5-carboxymethylaminomethyl-2-thiouridine(34)
                     oxidoreductase MnmC"
                     /protein_id="HBC0630978.1"
                     /translation="MKHYAIQPANLEFNAEGTPVSRDFDDVYFSNDNGLEETRYVFLG
                     GNQLEARFPEHPHPLFVVAESGFGTGLNFLTLWQAFDQFREAHPQAQLQRLHFISFEK
                     FPLARTDLALAHQHWPELAPWAEQLQAQWPLPLPGCHRLLLDEGHVTLDLWFGDINEL
                     TSQLDDSLNQKVDAWFLDGFAPAKNPDMWTQNLFNAMARLARPGGTLATFTSAGFVRR
                     GLQEAGFTMQKRKGFGRKREMLCGVMEQTLPLPCSTPWFNRTGSNKQEAAIIGGGIAS
                     ALLSLALLRRGWQVTLYCADEAPALGASGNRQGALYPLLSKHDEALNRFFSNAFTFAR
                     RFYDQLPVKFDHDWCGVTQLGWDEKSQHKIAQMLSMDLPAELAVAVEANAVEQITGVA
                     TNCSGITYPQGGWLCPAELTRNVLELAQQQGLQIRYQHQLQDLSRKDDGWLLNFAGDQ
                     QATHSVVVLANGHQISRFSQTSSLPVYSVAGQVSHIPTTPELAKLKQVLCYDGYLTPQ
                     NPANQHHCIGASYHRGSEDTAYSEDDQQQNRQRLIDCFPQAQWAKAVDVSDKEARCGV
                     RCATRDHLPMVGNVPDYDATLVEYASLAEKKDEAVSAPVYDDLFMFAALGSRGLCSAP
                     LCAEILAAQMSEEPIPMDASTLAALNPNRLWVRKLLKGKAVKAG"
     gene            complement(55345..55623)
                     /locus_tag="IRB70_001032"
     CDS             complement(55345..55623)
                     /locus_tag="IRB70_001032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcL family protein"
                     /protein_id="HBC0630979.1"
                     /translation="MIAEFESRILALIDGMVDHASDDELFASGYLRGHLTLAIAELES
                     GEDHSAQAVHTTVSQSLEKAIGAGELSPRDQALVTDMWEHLFQQASQQ"
     gene            complement(55657..56205)
                     /gene="epmC"
                     /locus_tag="IRB70_001033"
     CDS             complement(55657..56205)
                     /gene="epmC"
                     /locus_tag="IRB70_001033"
                     /EC_number="1.14.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P hydroxylase"
                     /protein_id="HBC0630980.1"
                     /translation="MNSTHHYEQLIEIFNSCFADDFNTRLIKGDDEPIYLPADAEVPY
                     NRIVFAHGFYASAIHEISHWCIAGKARRELVDFGYWYCPDGRDAQTQSQFEDVEVKPQ
                     ALDWLFCVAAGYPFNVSCDNLEGDFEPDRVVFQRRVHAQVMDYLANGIPERPARFIKA
                     LQNYYHTPELTAEQFPWPEALN"
     gene            complement(56205..57014)
                     /locus_tag="IRB70_001034"
     CDS             complement(56205..57014)
                     /locus_tag="IRB70_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBC0630981.1"
                     /translation="METFNSLFMVSPLLLGVLFFVAMLAGFIDSIAGGGGLLTIPALM
                     AAGMSPANALATNKLQACGGSISATIYFIRRKVVSLSDQKLNIAMTFVGSMSGALLVQ
                     YVQADVLRQILPILVICIGLYFLLMPKLGEEDRQRRMYGLPFALVAGGCVGFYDGFFG
                     PAAGSFYALAFVTLCGFNLAKATAHAKLLNATSNIGGLLLFILGGKVIWATGFVMLVG
                     QFLGARMGSRLVLSKGQKLIRPMIVIVSAVMSAKLLYDSHGQEILHWLGMN"
     gene            complement(57014..57838)
                     /gene="mepA"
                     /locus_tag="IRB70_001035"
     CDS             complement(57014..57838)
                     /gene="mepA"
                     /locus_tag="IRB70_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-insensitive murein endopeptidase"
                     /protein_id="HBC0630982.1"
                     /translation="MNKTAIALLALLASSASLAATPWQKITQPVPGSAQSIGSFSNGC
                     IVGADTLPIQSEHYQVMRTDQRRYFGHPDLVMFIQRLSRQVSNLGMGTVLIGDMGMPA
                     GGRFNGGHASHQTGLDVDIFLQLPKTRWTSAQLLRPQALDLVSRDGKHVVPALWKPEI
                     FSLIKLAAQDKDVTRIFVNPAIKQQLCLDAGTDRDWLRKVRPWFQHRAHMHVRLRCPA
                     DSLECEDQPLPPPGDGCGAELQSWFEPPKPGTTKPEKKTPPPLPPSCQALLDEHVI"
     gene            complement(57842..58927)
                     /gene="aroC"
                     /locus_tag="IRB70_001036"
     CDS             complement(57842..58927)
                     /gene="aroC"
                     /locus_tag="IRB70_001036"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBC0630983.1"
                     /translation="MAGNTIGQLFRVTTFGESHGLALGCIVDGVPPGIPLTEADLQHD
                     LDRRRPGTSRYTTQRREPDQVKILSGVFEGVTTGTSIGLLIENTDQRSQDYSAIKDVF
                     RPGHADYTYEQKYGLRDYRGGGRSSARETAMRVAAGAIAKKYLAEKFGIEIRGCLTQM
                     GDIPLEIKDWSQVEQNPFFCPDPDKIDALDELMRALKKEGDSIGAKVTVVASGVPAGL
                     GEPVFDRLDADIAHALMSINAVKGVEIGDGFDVVALRGSQNRDEITKDGFQSNHAGGI
                     LGGISSGQQIIAHMALKPTSSITVPGRTINRFGEEVEMITKGRHDPCVGIRAVPIAEA
                     MLAIVLMDHLLRQRAQNADVKTDIPRW"
     gene            complement(58962..59894)
                     /gene="prmB"
                     /locus_tag="IRB70_001037"
     CDS             complement(58962..59894)
                     /gene="prmB"
                     /locus_tag="IRB70_001037"
                     /EC_number="2.1.1.298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3 N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBC0630984.1"
                     /translation="MDKIFVDEAVNELQTIQDMLRWSVSRFSAANIWYGHGTDNPWDE
                     AVQLVLPSLYLPLDIPEDMRTARLTSSEKHRIVERVIRRVNERIPVAYLTNKAWFCGH
                     EFYVDERVLVPRSPIGELINNKFAGLISKQPQHILDMCTGSGCIAIACAYAFPEAEVD
                     AVDISPDALAVAEQNIEEHGLIHNVIPIRSDLFRDLPKVQYDLIVTNPPYVDAEDMSD
                     LPNEYRHEPELGLASGTDGLKLTRRILGNAADYLADDGVLICEVGNSMVHLMEQYPDV
                     PFTWLEFDNGGDGVFMLTKEQLLAAREHFAIYKD"
     gene            60060..60611
                     /gene="smrB"
                     /locus_tag="IRB70_001038"
     CDS             60060..60611
                     /gene="smrB"
                     /locus_tag="IRB70_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease SmrB"
                     /protein_id="HBC0630985.1"
                     /translation="MKKKTTLSEEDQALFRQLMAGTRQLKQDTIVHRPQRKKISEVPV
                     KRLIQEQADASHYFSDEFQPLLNTEGPVKYVRPDVSHFEAKKLRRGDYSPELFLDLHG
                     LTQLQAKQELGALIAACRREHVFCACVMHGHGKHILKQQTPLWLAQHPHVMAFHQAPK
                     EYGGDAALLVLIEVDEWLPPELP"
     gene            60697..62055
                     /locus_tag="IRB70_001039"
     CDS             60697..62055
                     /locus_tag="IRB70_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000981116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBC0630986.1"
                     /translation="MMNIRTLKLTNLGRFEELDVHLAPVEEFKSNVTVFIGNNGAGKT
                     SILKSLATSLSWFVARVRTEKGNGSPIPEDAILNGRSSATIELQVLNTHPATEAATPY
                     RWLLARTASGKKSTTASSLQEASQLAAFYRDQYTQNSGASFPLIAFYPVERVVLDVPL
                     KIKERHNFLQLDGYDNALNQGIDFRRFFEWFRNREDAENESGLPQDVLDKLSTRIDLD
                     NAVLNALTAIMASSRDRQLTAVRTAISRFMPGFSNLRVRRKPRLHMSIDKNGQTLNVL
                     QLSQGEKSLMALVGDIARRLAMMNPMLENPLNGEGIVLIDEVDMHLHPTWQRTIIQRL
                     TTTFPHCQFVLTTHSPLVISDCKDVLVYSLDDGELTQLPSLYGQDANTVLLNVMDTDI
                     RNATVAEKLNDLLDLIQKNDFINANALLNTLSLELPENHLELVKARMLLRKQEIKHAR
                     NN"
     gene            62039..62698
                     /locus_tag="IRB70_001040"
     CDS             62039..62698
                     /locus_tag="IRB70_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0630987.1"
                     /translation="MREITKGQPPASLQQWVRAKPRDKNANQWFQELYAQKKWDIVGD
                     LSQQCAQEQFYLCAYCCDRVTGTNRDTVNEHVEARDLAPARSLEFTNIVASCKTKGQC
                     DDSHKNQPLLLTPLMPECETEFIFKISGRIEGTTPRAIDAIKVLNLGDSERNNRALIE
                     KRKQLSDSLLWANGIAPSEGLEDDDLLQAVIDELLTPVDGYLAPFAPVVANILKNWMT
                     A"
     gene            complement(62740..63579)
                     /locus_tag="IRB70_001041"
     CDS             complement(62740..63579)
                     /locus_tag="IRB70_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001317961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2544 domain-containing protein"
                     /protein_id="HBC0630988.1"
                     /translation="MKKWMMFFASLILLVMSVGTPKSYARDKLTSATFDSVKIYYGMG
                     RAGFTTGALHVTVLTPGEVAYGVYNTTGYIGTDARVVSWTGSGPAPTLTLVDYSSTDN
                     SFCPGINTTLFRCAYETFKVTVQSDNYGCPWIASFYEVSDQHAYGIYTGPTDHATACP
                     TIPVTSFDISWNENYVSHSKALQLQSNGSTITTTLSTYLMQDGKLCDGSVFDNRGAYC
                     RVVSELLTFTSYGCDKSTVTVSPTRHPVTDKQLHDIVVKVNTSSRQPIDSTCRFQYVL
                     NEL"
     gene            complement(63581..64105)
                     /locus_tag="IRB70_001042"
     CDS             complement(63581..64105)
                     /locus_tag="IRB70_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630989.1"
                     /translation="MTKKHALVFISSLLLLCSSTAPAVDNLHFTGNLLGKSCTPVING
                     SLLAEVQFPTIAASDLMHLGQSDRVPLVFQLKDCKSSTLFSVRVTLAGTEDSELPGLL
                     AIDASSSASGVGIGIETAAGAAVPINDTTGVTFPLNQGSNTLNFNAWLQTKSGRDVTP
                     GDFSATATATFEYF"
     gene            complement(64102..64572)
                     /locus_tag="IRB70_001043"
     CDS             complement(64102..64572)
                     /locus_tag="IRB70_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630990.1"
                     /translation="MKRISLLMLWGFCSMALSNVTFHGYLVQPPNCTISDGETIELTF
                     QDVNIDDINGSNYEQIVPYRITCDTPVRDPLLEMTLSWSGTQSDFDDAAVSTDIAGLG
                     IRLKQAGQSFKLNTPLVVDETALPALTAVPVKKSGVDLPEANFEAWATLQVDYQ"
     gene            complement(64569..65060)
                     /locus_tag="IRB70_001044"
     CDS             complement(64569..65060)
                     /locus_tag="IRB70_001044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630991.1"
                     /translation="MKGSWAWLLVGCIGSCSVTAGSKSVDMILRVLVDAPPPCTVTGA
                     EVEFGNVVITRIGGVNYKRPIDYKLVCNNLAMDDLRLQMQAATVVINGETVISTGIPG
                     FGIRIQKASDSSILDLTSGAWLPFNFSSGAPALEAVPVKQSGTSLTAAEFSASATIVV
                     DYQ"
     gene            complement(65077..65829)
                     /locus_tag="IRB70_001045"
     CDS             complement(65077..65829)
                     /locus_tag="IRB70_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBC0630992.1"
                     /translation="MSYKLSSSMVVSTALAALLSTVSLAAHASVTPDRTRLVFNESDK
                     SISVTLRNNNEKLPYLAQSWLEDEKGNKITSPLAVLPPVQRIDAMMNGQVKIQALPDI
                     HTLPSDRESLFYYNVREIPPKTGKANTLQIALQTRIKLFWRPKALEKIDMRKPWQFKV
                     TLTRSGQDYTVNNPTPYHVIISDASTQKKGPTAAGFKPLVMSPKTSQPLKAKMDSAPV
                     LTYINDYGARLPLIFRCEGDTCKVDEDQSSKG"
     gene            complement(65849..68500)
                     /locus_tag="IRB70_001046"
     CDS             complement(65849..68500)
                     /locus_tag="IRB70_001046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBC0630993.1"
                     /translation="MPNHSNFRLRGIACYIALAISGGSVNAWADDSIQFDPRFLELKG
                     DTKIDLGKFSKKGYVDAGKYNLRVFINKQPLSDEYDINWYVSENDPTKTYACLTPELV
                     AALGLKEGIAKSLQWTHNDECLKPGQLDGMEVENDLSQSALLLTVPQAYLEYTSSDWD
                     PPSRWDDGIPGLIADYSLNAQTRHQEQGGEDSHDISGNGTVGANLGAWRFRADWQSDY
                     QHTRSNDDEDDDSSNSTTSKNWDWSRYYAWRALPSLKAKLSLGEDYLNSDIFDGFNYI
                     GSSVSTDDQMLPPNLRGYAPDVSGVAHSSAKVTISQMGRVLYETQVPAGPFRIQDIGD
                     SVSGTLHVRVEEQNGQVQEYDVTTASMPFLTRQGQVRYKVMMGRPEDWNHKTEGGFFS
                     GGEASWGVADGWSLYGGALADEHYQSAAMGVGRDLAQFGALAFDVTHSHVNLDHDSAY
                     GKGKLDGNSFRVSYAKDFDELNSRVTFAGYRFSEKNFMTMSEYLDANQSDMARTGNDK
                     EMYTITYNQNFAAAGVSIYLNYSHRTYWNRPEQTNYNLMFSHYFNMGSIRNMSISVTG
                     YRYEYDDNADKGMYLSMSIPWSDSSTVTYNGSYGSGSDSSQVGYFKRVDDATHYQVNV
                     GTSEQHGSVDGYLSHDGSLAKVDLSANYHEGEYRSAGIALQGGATLTAHGGALHRTQS
                     MGGTRLLIDADGIANVPVESNGAPVYTNMFGKAVVADINNYYRNQAYIDLNNLPEDAE
                     ATQSVVQATLTEGAIGYRKFKVISGQKAMAVLRLRDGSYPPFGAEVKNDEQQQVGIVD
                     DEGNVYLAGVNAGEHMTVFWEGSAQCEIVLPKPLPADLFSGLLLPCEQKGTAAPDSSA
                     PDIKPVIQDQTRQVTPTEAPTSISATQ"
     gene            complement(68581..69147)
                     /locus_tag="IRB70_001047"
     CDS             complement(68581..69147)
                     /locus_tag="IRB70_001047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000032634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0630994.1"
                     /translation="MSKFAKTAIAAAMVMGAVVSSSAFAAGNNGTARFYGTIEDSPCS
                     IVPDDHKLEVDMGDIGAAKLTGGGTTTPKDFQIRLQDCVFSTETNMETTFTGTNYAGP
                     ANTDNYALFNVDSGVAMKNVSLVIGDTHGKGYKVGEKIVQPIVMDASTSKGKDKQTLN
                     FKAWLVGETEAPDLGQFETLTTFQITYL"
BASE COUNT        17140 a        18929 c        17448 g        16010 t
ORIGIN      
        1 aattttcttt tattatatta attctgtttt cactccctct gattattttt taccaaccct
       61 gggtcaatgc attaccgcca acgccccgac acgcaagtcc tgagcaatta gaaaaaacag
      121 ttcgttatct tacacaaact gtgcatcccc gtagtgccga caatattgat aatctgaaaa
      181 ggtccgcaga gtatataaaa gaggtcttta tcagtagcgg tgccagagtt accgcgcagg
      241 acgtccccat tacgggaggt ccctacaaaa acattgttgc tgattatggt cctgccgatg
      301 gaccgctgat tattattggt gcgcactatg actctgtcag cagttatgaa aacgatcaat
      361 tgacctatac gccgggcgcg gatgataacg ccagcggcgt ggcaggatta ctcgaactgg
      421 cacgtttgtt acagcagcaa gcaccgaaaa ctggcgtgca gctggtcgcc tatgcgtcgg
      481 aagaaccgcc cttctttcgt agcgatgaaa tggggagcgc ggtacatgca gcttcgcttg
      541 agcgtccagt gagattaatg atagcgctgg agatgattgg ctattacgac tctgcgcctg
      601 gtagtcagga ttacccttac ccggcaatgt cctggcttta tcccgatcgg ggagacttta
      661 ttgccgtggt cggcagaatg caggatatca acgccgttcg tcagctaaaa gcggcattgt
      721 tgtcatctca ggatttatct gtttattcta tgaatgcccc agggtttatt cccggtattg
      781 atttctctga ccaccttaat tattggcaac acgatattcc cgccgtaatg attaccgaca
      841 ccgcttttta tcgtaataaa caataccact tgcccggtga taccgcagac agattgaatt
      901 atcagaaaat ggcccaggtc gtggatggcg ttatcacctt gttatacaac agtaaacaat
      961 aaaattttct cgaggcgggt ccagaaaaag caacatgcgc attttatttt ccctcatctg
     1021 ttttaagatg cgaaacatga aattcaacgg aggaaaaata aatgggaatg attggctatt
     1081 ttgcggaaat cgactcagaa aagattaacc aactgcttga gtcagctgaa aaacctttaa
     1141 tggacaatat tcatgacacg ctttcaggat tacgccgact ggatattgat aaacgctggg
     1201 attttttaca ttttggcctg acaggcacct ctgcttttga tcccgcgaag aatgatccgc
     1261 tgagtcgtgc cgtgcttggt gaacacagcc tcgaagatgg catagatggt ttcctggggt
     1321 tgacctggaa tcaggagtta gctgcgacaa tcgaccgcct ggaagctctt gaccgaaatg
     1381 tgctgcgtaa acagttttcc attcagcgac tcaatgaaat ggagatttat ccgggagtaa
     1441 ccttttcaga agagttagag gggcaactct ttgcatccat catgcttgat atggaaaaat
     1501 taattagcgc ttatcggcgt atactgcgac aggggaatca tgcgctgacg gttattgttg
     1561 ggtgatgggg tcagggcacc aaaaaaaacc gccgaacatg tcggcggctt tctgacttac
     1621 gaactgacag cttacatcag cggcattgct aaccgcacaa tgctaatcag cggttgcggc
     1681 catataccca gcaccagtac caacagtgca gagatcagca ccacgatacc gcccgcgctg
     1741 tactgccagt ttgatggtgc atcgcgaccc ggttgttccg gggcatgcag gtataagctc
     1801 accgctacgc gcaggtagta gtagaggccg attgccgaac cgacaaccac cgcgcccacc
     1861 agccaccaca agtgtgcctg gacaccgacc gccagcacgt agaacttacc gataaagccc
     1921 agcgtcattg ggatacccgc cagagacagc atcatcaccg tcatcactgc cgcgaggatc
     1981 ggacgatgcc agaacagacc gcggtaagag aacagggaat cagcatccgg gccacgatac
     2041 gggctggaca tcaggctgac cacgccgaac gcgccgaggc tgctgaacag ataaccggcc
     2101 aggtaaaccc ctaccgcttc catcgacatc tcgcccgttt gcagcgcaat cagcgccacc
     2161 agcagatagc cgagatgaga gatagatgag taaccgagca gacgtttgat attggtctgg
     2221 ctcagcgcca tcaggttacc gaagatgatg gaggcaaagg cgataatcgc cagcaccacc
     2281 cgaatcgctt cgctgtcacc caccggtgcg tagaggaaca gacgcatcac cacaccgaag
     2341 atagcgattt tgctcgccgt cgccaggaaa gtggaaaccg gcgcaggcgc gccctggtat
     2401 acgtctggcg tccacaggtg gaacggcacc agagagagtt tgaagccgag gccaacaatc
     2461 atcaggccga aacctgccag caacagcggc tcgttgagca taccgtcgcc gaggttttta
     2521 cccagcgcga caaacgacag gtcgccagac tgcgcataca ccagcgccat accgaacagc
     2581 aggaaagaag acgctgcggc agaaaggatg gtgtatttga tactggcttc cagcgaacgt
     2641 ttctggcgga aagcgtaacc gaccaggcca aacagcggca aagagatcag ttcaataccg
     2701 aggaacaaag acgccagatg gttggcattc gccagcagga tcccgcccag cgcggcaatt
     2761 aacaccaaca ggtagaactc atccttgttg tcgttatagc cttcaagcca cgggtaggcg
     2821 aaagtacagg tggcgaggct cgccaacaat accagcccgg tgtaaagcat ggcgaaacca
     2881 tcaacgcgca tcagcggcgt aacgtccata gcgcccgcct ggccgacaaa ccagagcgaa
     2941 accagcgccg cgttaagccc aataaccgag agcgtagcgt tgaggaaatg attgcgtcgc
     3001 cacgcaatgg agagcatcac caccaccacc gtcaagccga cgatcagcaa cggtagcagt
     3061 gcgatcaggt tttgtggagt tattgtcatg gcgatttacg gccttgtagt agtaacggaa
     3121 ttaacaaacc actgctggat attgccaatc gcggagtgcg aggtatccag aatcggctgc
     3181 ggatagaagc ccagcagtac cagcagcacc accagcaaca ggatcataaa cagctcgcgc
     3241 agcgacatcc ctggcagttc ctggctggca atctggcttt tcgctttacc gaagtaagcg
     3301 cgatgaagca tcgccagcga ataaacagat gcaaagacca gcccaaaggt agagataacg
     3361 gtaatcaccg ggacaacctg gaagctgccg aatagaatca taaattcgcc gacgaagtta
     3421 ccggtgcctg gcatcccaag cgttgccacc gcaaagaaca gcgacagtgc cggcagccat
     3481 ttcatcttgc tccacagacc gcccatcatg cgcatgtcgc gggtatggat acgttcataa
     3541 agctgaccgc agagaataaa cagacccgcc gccgacaagc cgtgcgcaat catctgaatg
     3601 accgcgccct ggtaggccaa ctggctgccg gtgtagatag caatcagcac gaaacccatg
     3661 tgggaaaccg aggtgtaggc gatcagacgt ttgatatcgg tctgggcgaa ggccatccac
     3721 gcaccgtaga agatgccgat aacacccagc cacatagcga ttggcgcgaa ctctgccgac
     3781 gcgttcggga acagcggtag ggagaaacgc agcagaccgt aagcggcggt tttcagcaag
     3841 atccccgcga ggtcaacgga accggcagtc ggtgcctggg agtgcgcatc tggcagccag
     3901 ccatgcagcg gaaccaccgg cattttcacc gcaaatgcga tgaagaagcc cagcatcaac
     3961 agatattcca caccactgga cattggcgta ttcagcagct cttcatagtt gaaggtccag
     4021 acgccagtcg cattgtagtg aacaaaaacc agcgccagga tggcgatcaa catcaccaga
     4081 ccactcgcct gggtgtaaat gaagaacttg gttgccgccg tgatacgcgt tttaccatca
     4141 gaggctttat gcccccacag tgcgatcagg aagtacatcg gcaccagcat catttcccag
     4201 aagaagaaga acaggaacat gtcgatggca aggaacacgc cgataacgcc gcccaggatc
     4261 cacatcaggt tgaggtggaa gaagccctga tatttttcga tctctttcca cgaacagagt
     4321 accgccagca cgccgagcag accggtcagc acgaccatca gcagcgacag cccgtcaatg
     4381 gcgagatgga tagagatacc aaaacgcggg atccacggca tctcgaattc agactgccac
     4441 tgcggaattc cggcggattg cgtcagtgaa taaccgccct gcaaccacag ttgcagcgac
     4501 agcgccagcg tcaatcccat ggtgatcagc gcgatccagc gcggcacctt gacgccaaag
     4561 cgttcggtct gccagcacag gaagccgccg ataaagggaa ttaatattag ccagggtagt
     4621 aacatggcga tctttattcc ttgtaaaagt cccgtcagga ccggattttc aacgaattct
     4681 cacgacagaa aattctcttc ggattgtggt tgtagtgtcg gatgcgccgc gaaggcggct
     4741 tatccgacct acgttcttat atgcccaggg gcaagcccac aatccttaac tcaacgcagt
     4801 accatcaaca gtgccagcac cacgaccgca ccgatgctca tggatgccac ataccagcgc
     4861 agataaccgt tctcgcttaa cagcagacct ttacctgcaa agcgggaaag gacagccggg
     4921 atgttcatca ttgagttcag cggatcgcgt ttcagcaacc aggcaatacc caggaacggc
     4981 ttgacgaaca ctttgtcgta cagccagtca aagccccagg cgttgtacca ccaggtgccc
     5041 agcagacggc ccggcgcact gttggcgatg gaggtcacca gagtacgttt acccagccac
     5101 agccaggcag ccagcagaat gccgaccacc gcgaccacgc cagaggtaat ttccagggtc
     5161 aacatgctgc cgtgcgccag ctctgtcgtt tgcggaagca cgccctgcag cggcggtaca
     5221 atcagtgcgc caacgaaggt ggaaaggatc agcagcacaa tcagcggcag gctgtgagtt
     5281 acccctttca cggcgtgagc gtgaatttgt tcttttccgt ggaagacgat gaaaatcata
     5341 cggaaggtat aaagcgaggt cataaacgca ccgaccagac ctgccaccat cagattgata
     5401 tgaccattcg ccatcgcacc cgcgaggatc tcatccttac tgaagaagcc cgcagtgacc
     5461 agcggcagtg ccgacagtgc tgcgccgccc accaggaagc agagataaac cagcggaata
     5521 gatttacgca gaccgcccat cttgaagatg ttctgttcgt gatggcaggc cagaatgacg
     5581 gaaccggatg ccaggaacag cagcgcttta aagaacgcgt gagtcatcaa gtggaaaatc
     5641 gccgcatccc atgcctgcac gccaagcgcg aggaacatgt agccaatctg gctcatggta
     5701 gagtaagcga gaacacgttt gatatcggtc tgtaccagcg cggcaaaacc ggccagcagc
     5761 agcgtaaccg ccccaacaat gcccaccaga tgcagaactt ccggcgtcat caggaacagg
     5821 ccgtgggtac gggcgatcag gtagacaccc gcggttacca tcgttgcggc gtggatcagc
     5881 gcggagacag gcgtcgggcc cgccatcgcg tcggcaagcc atgtctgcaa cggcaactgc
     5941 gcagatttac cgaccgcacc gcccagcagc atcagcgtcg cccacatcag catgttattg
     6001 ccatcagcaa agtgcgctgg tgccagttcc accatttcgc ggaagttcag ggtgcccagt
     6061 tcgttgtaga gaatgaacag cgcgaaagcg aggaacacgt cacccacacg ggtcacgacg
     6121 aacgctttca ttgccgctgc gccattcttc ggatcggtgt aatagaaacc gatcagcaga
     6181 taggagcaca ggcccacgcc ttcccagccg aggtacatca gcagcaggtt gtcggcaagc
     6241 accagaacca ccatgctggc gatgaacagg ttagtgtagg cgaagaagcg agagtagccc
     6301 tcttcaccgc gcatgtacca ggaggcgtac atgtggatca ggaaacccac acctgtgacc
     6361 accgagagca tagtcagcga caggccgtcc agcaccaggt taaaaccgat gttaaagtcg
     6421 cctaccgaca tccacgtcca cagcggctgg ctgtatgcct gctcaccgtt agcgaagaag
     6481 tcaacgccga taaaggcagt taccagcgcc gccaggccca cagagccaac gcccacgatc
     6541 gccgagacgt tttcagacca acgcccacgg gagaacgcca gcaggacaaa gccaatcaat
     6601 ggcaaaataa tggttaaggc aagcatgttc atccgcgcat ctcacttact gaatcgatgt
     6661 tcaggttctg gcgacgacgg tgaagttgca gcagcagcgc aaggccgata cttgcttctg
     6721 ccgccgcgag gctgatggcg agaatgtaca tcacctgacc gtcggtctgg ccccagtagc
     6781 ttccggcgac cacaaaggcc agcgcggagg cgttaatcat gatttccaga ccaatcagca
     6841 taaacagcag attgcgacgg ataaccagac cggttaagcc aagaacgaat aagattgccg
     6901 cgaggatcag tccatgttgt aaggggatca tgcgtgctcc tccgtttttc ttttcgcgct
     6961 gtcgtcttta cgattactca gcacttcacc cgctcgctct tcacgaccaa cgtggaaggc
     7021 cacaaccaga cccgcgagca gcagcataga agccagttcc accgccagta cgtaaggccc
     7081 gaacagcgta atacccactg ctttagcact gattggcgta ccgtcgatac cctgatcatt
     7141 aacaccaagg atggcgtaaa caatcaccac cagcatgatg gccgacaaaa tcgccggacc
     7201 aatccacacc tgcggtttca gccactggcg ttcctgttcg atttctgaac cgcccaggtt
     7261 gagcatcatc accacgaaca cgaacagcac cataatggca cccgcataga cgataatttc
     7321 cagcgcaccg gcgaagtaag cgcccagtga gaagaacacc ccagagatcg ccagcagcga
     7381 aataatcagg tacagcagtg cgtgtaccgg attggtatga gtgatcactc gcaaggtcgc
     7441 aagtatggct atcaggccac agatataaaa agcgaactcc attgcccctc tccttacggt
     7501 aacaggctct tgacgtcgat aggcttggct tcgttctctg cttcgccctt atctttgccg
     7561 tcgattgcca tacctgccat ccggtagaag ttatattccg ggtatttgcc cggaccggag
     7621 atcagcagat cctctttctc gtaaaccaga tcctggcgct tgtattcccc catttcgaaa
     7681 tccggggtta actgaatcgc cgtggtcgga caggcttctt cgcacagacc acagaaaatg
     7741 cagcgtgaga agttgatgcg gaaaaattcc ggataccagc gaccgtcttt ggtttctgct
     7801 ttttgcagcg agatacagcc gaccgggcag gctaccgcgc agaggttaca ggctacgcaa
     7861 cgctcttcgc cgtccggatc gcgggtcaga acgatacgac cacgataacg gggcggcaga
     7921 tagaccggct cttccgggta cattcgcgtt tcgcgtttgg cgaacgcgtg caggccgatc
     7981 atccagatac tacgaacctg ggtgccgaaa cctactaaca attcttttaa ggtcatggtc
     8041 ttattgcccc ttattgcgcc tgccagagaa tgacagccgc cgttaccagc aagttgatca
     8101 gcgtcagcgg caggcagatt ttccagccga aggacattac ctggtcataa cgcggacgcg
     8161 gtaacgacgc acgaatcaaa atgaacatca tcataaagaa cgcggttttc agcgcgaacc
     8221 agatgaatgg cggtaacaac gggccttgcc agccaccgaa gaacagcgtc accatcagtg
     8281 cagagatggt cacaatcccg atgtattcgc ccacgaagaa cagaccgaac ttcatgccgg
     8341 aatattcaat gtggtaacca tccgccagtt cctgctcggc ttccggctgg tcaaacgggt
     8401 gacggtgaca caccgccacg cccgcgatgg caaaggtaat aaaaccaaag aattgcggga
     8461 tgacgttcca cacatgcgcc tggctgttga cgatgtcggt catgttgaat gaaccggcct
     8521 gcgccaccac gcccatcagg gaaagcccga ggaacacttc gtagctcaga gtctgcgcag
     8581 aagcacgcat cgcccccagc aacgagtatt tgttgttact tgaccagccc gcaaacagca
     8641 ccgcgtagac cgccagaccg gccatcatca ggaagaacaa aatcccgatg ttcaggtcgg
     8701 caaccaccca acccggactg actggcacaa tcgcaaaggc cagcagcagc gaggtaaagg
     8761 caatcatcgg cgccagggta aagatgacgc gatccgagaa tttcgggatc cagtcttctt
     8821 taaagaacat tttgatcatg tccgcaacca gctggagcga accgccccag ccaacacggt
     8881 taggtccgta acggttctgg aacagcccca gcaggcgacg ttcgccaaag ctcatgaaag
     8941 ccccacaggt gacaaccacc agcaggatca ccaccgcttt gaggatggtc agcaggatct
     9001 caatcagttc cggtgttatc caactcattg ctgtgcctcc ttgagatcct caagatgcgc
     9061 gccagccagc accggagcaa tgccggacat acccatcggc aagcccacct gccctgccgt
     9121 cagtccttcg gcgatttcaa ccggcagcgt gaccgtgttg ccatcgtaac taaaggagac
     9181 gcgtgtacct gcgttcacac ccaacttcgc ggcatccgct gggttgagtt tgatgtacgg
     9241 ctgcggcata cggctctgga agaccggagc acgctgtgac aattcatcgc tgccaaacag
     9301 gtggtaatac ggcgcgatac gccatttccc gtcctgcggc tggaagcgtg ccggtacgct
     9361 ggtgaagtaa tccagaccat tttcgctggt ttcaaacaga cgcacgcccg gatcgccaaa
     9421 gcgcagtttg ccgcccactt cgtcctggaa tttgttccac gcctgcgggg agttccagcc
     9481 cggtgcccag gcaaacggca cttgcgaacg gtgcgcggtc ggctggttgt taccttccat
     9541 cgagaaggtg aacatggtgt caatatcctg cggctgacgc ggctcatgaa cgctgatatt
     9601 ggcgcgcatg gcggtacgac cgctgtaacg gtgcggctca cgggccagtt tctgcccacg
     9661 aatacggaat gtcgcatccg gcgcagcatc tttgataccc gccagttccg ggattttcgc
     9721 cacaacagcg tcaatcacat ggtcgagctg cgtccagtcc acttcacggc tcagcagggt
     9781 gctgtgcagc gagtgtaacc aacgccagct ttccagcatg acagttttgc tgtcgtaata
     9841 agccggatcg taaacctgga agaaacgttg ggcacggcct tcgttgttaa tcaccgtacc
     9901 gtcgctttca gcaaagctgg cagcagaaag taccagatgg gcgttttcca taatcgctgt
     9961 gcgttgatgg tcaaccacca tcaccagcgg cgctttagcc agcgcagcat tcacgcgggt
    10021 agcagaagcg tgacgatgca gatcgttttc caacaccacc accgcgtcgg cgcgtccggt
    10081 ttccagttcg gttaacgctt cttcaagcga tccaccgccc ataatgccca gccccatgct
    10141 gttgacggaa cgggcaatca tggtgatacc gacgtcagcg ccgcgacctt tcagggcttt
    10201 cgccacgtta gccgctgcct gaatcacttc agcgctacca gcgttcgtcc cggagataat
    10261 caacggtttc ttcgcaccag ccagtgcctg cacgatgacg tcgattttgc tttgcagctc
    10321 aggttcgata ccgtcaaccg ctggcgcgga gttatccagc gcatgggcga tggcaaaacc
    10381 taaacgcgcc tgatcttcaa ccggtgcgcg gtaagtccac gccgcgatat catccagacg
    10441 ggtgtcatca acgttggtaa caaacagcgg atgcttcgca cgttgaccga tgttgaggat
    10501 tgccgcaatc tgccagtcag ccactttctg tgctgccgcc atttcgcgtg ctttaccttt
    10561 caccgcctga cgaactgcca gcgcgacgcg cgcgccggtc tgggtaacgt cttcgcccag
    10621 caccagtacc gcatcgtaag attcaatttc gcgtaaggcc ggagtataaa tgccgccttc
    10681 gcgcagaact tttagcgcca gttgcagacg ttcctgctca ccgtgagcga taccggtata
    10741 gaagttttct tcgcccacca gctcacgcag cgcaaagttg ctttccacgc tggcacgcgg
    10801 agaaccaata ccgatcactt tcttcgactg acgcagaata tctgctgcgc cctgcattgc
    10861 ctgttcggcg ttgagggtaa tgaaatcatt gccacgacgc tgtactggct gacgcggacg
    10921 atctttcagg ttgacgtaac cgtaaccgaa acgaccacgg tcgcagagga agtagtggtt
    10981 taccgtaccg ttgtaacggt tttcgatacg acgcagttcg ccataacgct cgccggggct
    11041 gatgttacag ccgatggaac attgctggca gatgctcggc gcaaactgca tatcccattt
    11101 acggttgtaa cgctcggagt gcgttttatc ggtaaatacg ccagtcgggc aaatttcgac
    11161 caggttaccg gaaaattcgc tttccagcgt gccgtcttcc gggcgaccga agtagacgtt
    11221 gtcgtgcgca ccgtaaacgc ccaggtccgt accgtcagcg taatctttgt agtaacgcac
    11281 gcagcggtag caggcgatgc agcggttcat ttcgtgagag atgaacggcc ccaaatcctg
    11341 attacggtgg gtacgtttgg tgaaacggta gcgacggaaa ctgtgtccgg tcatcacggt
    11401 catatcctga agatggcagt taccgccttc ttcacatacc ggacagtcgt gcgggtggtt
    11461 ggtcattaac cactcgacca cactttcacg gaattgcttc gcttcttcgt cgtcaatgga
    11521 aataaaggtg ccatcggaag ccggtgtcat acaggacatc accaggcgac cacgcgtgtc
    11581 ttccgcgttt tggtattgct ttaccgcaca ctggcggcaa gcaccgacac ttcccagcgc
    11641 cggatgccag caaaagtaag gaatatcaag gcccagagac agacaagctt ccagcaggtt
    11701 gtccgctccg ttgacctcgt attctttgcc gtctacatga attgtagcca ttagcatgct
    11761 tccagttttc tcggtcaggg accgagcgtt aatcgaaatt cggttaccag cgctctttca
    11821 gcaggttcgg ctgaatccca ttaatcaaat gggtattgct gaacggctgt ttgattcccg
    11881 cctcaaattc ttcgcggaaa tatttgatgg cgctctgtaa cggctccact gcaccaggtg
    11941 cgtgggcaca gaaggtttta cccgggccta agaatcgaca cagttgctca agtgtttcga
    12001 tatcgcccgg ctgaccttcg ccacgctcca gcgcacgcag aattttcacg ctccatggca
    12061 gaccgtctcg gcacggcgta caccagccgc aggactcacg ggcgaaaaac tcttccaggt
    12121 tacgtaccag cgacaccatg ttgatttcat ggtcaaccgc catcgccagc gccgtaccca
    12181 gacggcttcc cgctttaccg atgctttcga attccatcgg caggtcaaga tgcgcttcgg
    12241 tcaggaaatc ggtgcccgca ccacctggct gccaggcttt gaatttcagg ccgtcacgca
    12301 taccaccagc gtaatcttca aggatttcac gcgcggtggt gccgaacggc agttcccaca
    12361 ggcccggatt tttcacccga ccggagaagc ccatcagctt ggtgccagca tctttgcttt
    12421 tcgagatgtt ctgataccac tccacgccgt tcgcgaggat cgccggaacg ttgcacaggg
    12481 tttcaacgtt gttgacgcag gtcggtttac cccatgcacc ggaggttgcc gggaatggcg
    12541 gcttcgagcg cgggttagcg cgacgccctt ccagggagtt gattaacgct gtttcttcac
    12601 cgcagatata gcgccctgcc ccggtatgga caaacagctc gaaatcgaaa cctgttccca
    12661 taatgttttt gccaagcaga cccgcttcgg tcgcttcggc aatagcacgg cgcagattca
    12721 ctgccgcttc aatatattcg ccacgcagga agatgtagcc acgatacgct ttcagcgcaa
    12781 acgcagaaat gagcatacct tccaccagca ggtgcggtag ttgctccatc agcaggcggt
    12841 ctttataggt gcccggctcc atttcatcgg cattacacag caggtaacgg atgttcatgg
    12901 attcgtcttt cggcatcagg ctccacttca ggccagtaga aaagcccgcg ccgccgcgcc
    12961 ctttcaggcc agagtcttta acctgattaa cgatttcgtc aggagacaac ccggtcagcg
    13021 ccttacgcgc gccttcgtaa ccgtttttac tgcgatattc gtccagccac actggctgtt
    13081 tgtcatcgcg cagacgccag gtcagcggat gcgtttcggg agtacggata atgtttttca
    13141 tttataccgc tccagcagtt cagggatcgc ttccggggtc agatgcgcgt gagtatcctc
    13201 atcgatcatc atgtttggcc ctttatcgca gttccccagg cagcaggttg gcagcagcgt
    13261 aaagcgaccg tcaaacgtgg tttgccctgg tttgatattc agttttttct ccagcgctgc
    13321 ctgaatgccc tggtaaccgt tgatgtgaca gaccacgctg tcgcaataac ggatcacatg
    13381 gcggcctact ggctggcgga agatctgact gtagaatgta gccacgcctt cgacatcgct
    13441 tgcgggaata cccagaacat cagcgatcgc gtggatcgcg ccgtccggca cccagccacg
    13501 ctgcttctga acgattttca gcgcttcaat ggacgccgca cgcgggtctt cgtagtggtg
    13561 catctcgtgc tcaatcgctt cacgctcagc cgcactcagc tcaaaagcct cggtttgtgg
    13621 ttgttgattc tcgtgcataa ttagcggtcc acatctgaca taacaaaatc gatactgccc
    13681 agataaacaa tcaggtcaga caccaggctg ccgcggatcg ccgccggaat ttgctgcaaa
    13741 tgcgcataac tcggcgtacg gatacgggtg cgataactca tggtgctacc gtcgctggtc
    13801 aggtagtaac tgttgatccc cttggtcgcc tcaatcatct ggaaggattc attggcaggc
    13861 atcaccggcc cccacgacac ttgcaggaag tgggtgatca gggtttcgat atgttgcaac
    13921 gtgcgctctt tcggcggcgg cgtggtcagc gggtgatccg ctttgaacgg gccttccggc
    13981 atgttgttga ggcactgctc aagaatgcgc agactctggc gcagctcttc cactttcagc
    14041 attacgcggg tgtagcagtc agaaacgcca ccacccaccg ggatttcaaa gtcgaagttt
    14101 tcatagccag aataaggacg cgccttacgc acgtcgaagt cgatcccggt ggcacgcagg
    14161 cccgcgccgg tggtgcccca ctccagcgcc tctttcgcgc cgtaagcggc aacgccctgg
    14221 gaacgacctt tcagaatggt attttgcagc gccgctttct cgtaagacgc cagacgtttc
    14281 ggcatccagt cgaggaactc acgcagcagg cgatcccaac cgcgcggcag gtcgtgcgct
    14341 acgccgccaa tacggaacca cgccgggtgc atacgaaaac ccgtgatcgc ttccaccaga
    14401 tcgtaaattt tctgacgatc ggtaaaggcg aagaacactg gcgtcatcgc gccgacgtcc
    14461 tgaataaagg tggagatata cagcagatgg ctgttgatgc ggaacagctc agaaagcatt
    14521 acgcgaatga cgttaacgcg atccggcacg gtgatcccgg ccagtttctc taccgccagc
    14581 acataaggca tttcgttaac gcagccgccg aggtattcga tacggtcggt atacggaatg
    14641 tagctatgcc aggactggcg ctcgcccatt ttctccgcac cacggtggtg gtagccgatg
    14701 tctggtacgc agtcgacaat ctcttcgcca tcgagctgca aaacgatacg gaaagcaccg
    14761 tgcgccgacg ggtggttcgg accgaggttg aggaacatga agtcctcgtt ttcggtgccg
    14821 cgcttcatcc cccactcttc cggtttgaag gtcagggctt ccatttccag atcctgtttg
    14881 gctttggtca gctcaaacgg cgagaattcg gtagcgcgcg ccgggtaatc tttacgcagc
    14941 ggatgacctt tccaggtttg cggcatcatg atgcggcgca aattaggatg accgtcgaaa
    15001 gtaatgccaa acagatccca ggtctcacgc tcataccagt tagcgttcgg gaacagtttg
    15061 gtgaaggtcg gtacgtgcag gtcgttttct gccagcgcca ccttcagcat gatgtcgcgg
    15121 ttacgatcga tagaaatcag atggtagaaa acggaaaaat ccgcggcagg taacccttcg
    15181 cggtgtgtgc gcagacgttc gtccatgccg tgtaagtcaa acagcatgac gtaaggtttc
    15241 ggcagtttct ttaagaaatc gccaacttcc agtaattgtt cacgcttgat ccacacaacg
    15301 ggaaccccgg tgcgagtcgc ctgaacagta aaggcatccg gcccaaaacg gttgcgcagt
    15361 tcgccaatca ccggatcatc aagatgatcg cgggtctgcc aggcgggttc ttgcgcggtt
    15421 aagtcggtca tattgttcac cattgcaaat ggtccgtggt gactgtcggc gcagtaagct
    15481 tcgcgaaata gatttaggaa taagcgaaga aaaatccctt tgccgacagg cgcaaattaa
    15541 atctcgtcag gtgtacgcag gttggttacg gcaatgcgtt caccgcgctt gcgttcgcgc
    15601 tctgattgca tattggcgcg ataaacgccc tgatcgccaa ccacccagga gagcggacga
    15661 cgttctttgc cgatagattc ctgcaacagc atcagtgcct gcatgtacgc ttcaggacgc
    15721 ggcgggcagc ccgggatata cacatcaacc gggatgaatt tatcgacgcc ctgcacaacg
    15781 gaataaatat cgtacatacc gccggagttg gcacaggcac ccattgagat aacccatttt
    15841 ggttccagca tctggtcata cagacgctga ataaccggtg ccattttggt aaagcaggtt
    15901 cctgccacca ccatcaggtc agcctgacgc ggcgaagcac gcaatacttc tgcgccaaaa
    15961 cgcgccacgt catgcaccgc ggtaaacgaa gtcaccatct caacgtaaca gcaggaaaga
    16021 ccgaagttat acggccaaat tgagttttta cgaccccagt taaccatgtc attgagcttg
    16081 cccataaaca cgtttttgtt aacttcttgc tccagagggt cggttacgat ctcctgcttt
    16141 tgcagggggt aacggtcgtt ctcaccgttg ggatctatgc gggtgagcgt ataatccatc
    16201 ttaatgcctc gcggttagcg ttgacgatta gcgatactgt tcgtttccgg gttcatacgc
    16261 tcgcggcgtg aacgcgcggg cgtccagtcc agcgcgccaa tacgcaccag ataaaccaga
    16321 cctgccagta acacaaaaat aaaaattgca gcttccacaa agcctaccca gccgctttcg
    16381 cggatagagg ttgaccatgc gaacagatac agcgcttcaa cgtcgaagat aacgaagaac
    16441 atggccacca gataaaactt ggcggacagg cgtaagcggg cggagccgac cgagtcgata
    16501 ccggattcaa acggaacgtt tttcgacctt gcgcgtgcgc gaccgcctaa aaaccaaccg
    16561 cctaccagca tcaggcaaca caggccaatg gcaacgataa gaaagatagc gaatgcccag
    16621 tgatgagcga tgacttcagt ggatgttgac atactcattg cttactcatc aaaagtagcg
    16681 ccagattcac tgctcttcac ggcagatgga cgccacatcg attcatgggg aggaataaaa
    16741 aaaaccttac aatcactgta gaaattcttt tatacagcta attgatgtgg tcttttactc
    16801 ctttctataa ccttttgtca actttaacaa aagtttcttc acattagttt acataatatc
    16861 aacaccatta gcatttaatg ccctttcacc ccagatcctt gacgactcca ggataattag
    16921 atgttgttga atcgtgtccg ttgtgaagca atggaaaaaa tacgggtcta ttttgacagg
    16981 aatttgtgtc gattcctccc cccaaaagag agtattttct tgatctgtga cacgcttttg
    17041 tcattccata acaaaaacgc agcaacaaat ttacgtattt tttaacatca ttgtagcagg
    17101 tgattttttt caggcgatta tttgtgcgtt caggacgtga atctctggtg actgaaaaat
    17161 gaacagtttt gtgcgttctg cacgatacga ggaaggcttt ttactaaaaa aaagccgctg
    17221 gggtttaaaa tccctccagc ggctcgtttt tacactattg ttccaggaat tatctatcgt
    17281 ccgtcgatta ctcgatatcc ctttcaatta acaatgagtc atctccttcc ggagcagaca
    17341 ttgggctgta ttgccacgga ttatggtagc tctccatcgc ctgatagatc acctgggcca
    17401 gctcattatt actggacggg tcatagcaca gcaaatattc ggtatcgggt agcggcggta
    17461 agccatctac tccactcagc acacgcaggt ccggactcat catctcgacc ggccttgccg
    17521 tcacgccaag accggctttt actgccgcac gaactgccgg aagcgtcgag gcgacataag
    17581 ccagtcgcca tggaatatct gctttattaa gcgtcgccag caccatatcg cgaaacgggc
    17641 taggatcatc cagcaataca agagggatcg gctcgccttt ttgcaatacg tattccgctg
    17701 cgcagtacca gtgtgttggc gaggtacgca ggttcaatgc cttaaacgtt gaaggacgat
    17761 gggtggttac catcaaatcc acttcctggg attccagcat ttctgccata taggcattac
    17821 gtttaacgcg gacatccagc gctagtttcg gataaaccga actcacgcga tttaacagga
    17881 aaggtaagat cgtatcggca gattcatctg aagcaccgat agttaacacg ccctgaagat
    17941 tactgaacat taatgatgag caggcctcat cattaaaacg cagaattttt ctggcgtaac
    18001 caagaagttg aatgccatgt tcagttaaca gtttgttgcg accgtgacga gcgaacagct
    18061 ctttcccaac gagttgttcc agacgctgca tttgctgact tacggcggac tgagtacgac
    18121 acacagcggc agctgcggca gcaaaagtgt tcagatcggc aacagcaaca aatgttctca
    18181 gcagatcgag gtcgaggtta attatcggac gatttgcact tatcatatat tatcacttac
    18241 tggcggctca tactgagctg gttaatgctg tgcacacaca aacaagcaat tccatttgta
    18301 atgtgcctcc ctggcagttt catccggaac ccggacgaaa gtaaaaatgc atatgagttg
    18361 cactaaaaaa gcgactcaca ttgttccgtt ataatgcctg aagtagatca cagaatatat
    18421 cttcaggaat cgcatatcta ttaagttact cactcttttg tatttatgac atgcgcgtgt
    18481 ttgtataaat gtaaatgtga gtccttgttc cactctcgtg cagcatcgct ggtcatacgc
    18541 gaacacgtac aaacagcaat ggtgaggcgg catcaagagc agggatccgt catttatgcg
    18601 agcattttac cccaaaaacc ttttatttat aagggtcatt gcgaattatc tgatgcaaag
    18661 ttatgttatg ttaggcaaag taatcttcta ttattaataa gcacaacaaa acctttttga
    18721 atattaaata ataattaatt agcatcatcc tcatacatta atcccgctta acaatagttt
    18781 cacaccttgc acccattacg acacatcgga aatcatcacg ctgttaaact ctccgtaatg
    18841 cggaaatatc atcatcacga ttcattagtg aattcttaaa cgaggcattt tcaaacaatt
    18901 atcttacaga taaaaaaacc acactcacaa ttaagaatca gaacaattca ctacataaca
    18961 ttaattatta agcatataca cctcattatt ttgccattat taagttatta acagcacaat
    19021 caagccttcc actctggcaa aatcttattc tgcagacctt caaaacgccg tcctggggga
    19081 gtacattgtt ctaagctgac ttccacggca gggagtggcg ataacagcaa aaaaggtcaa
    19141 gattcatgtc ccccattgaa aaatccagca aattagagaa tgtctgttac gacatccgtg
    19201 gtccggtgct gaaagaagca aaacgcctgg aagaagaagg taacaaggta ctgaaactga
    19261 acatcggcaa ccctgccccg ttcggttttg acgcgccaga tgaaatcctc gttgacgtga
    19321 ttcgcaacct gcctaccgct caagggtatt gcgattccaa agggctttac tccgcgcgta
    19381 aagccatcat gcagcactac caggctcgtg gcatgcgtga tgttaccgtg gaagatattt
    19441 acatcggcaa tggtgtatcg gagcttatcg ttcaggcaat gcaggcattg ctgaacagcg
    19501 gggacgaaat gttggttcct gcacctgatt acccactatg gaccgcggcg gtttcgctct
    19561 ccagcggtaa agcggtgcat tatctttgcg atgaatcctc tgactggttc ccggaccttg
    19621 atgatattcg cgctaaaatt acgcctcgta cgcgtgggat cgttattatc aacccaaata
    19681 acccaaccgg cgcggtatat tccaaagagc ttttaatgga gatagtggag attgcacgtc
    19741 agcataatct cattatcttc gccgatgaaa tttatgacaa aattctctac gacgacgctg
    19801 agcatcactc aattgcgccg ttggcacctg acctgctgac cattaccttt aacggcctgt
    19861 cgaaaacata ccgcgttgca ggcttccgtc aggggtggat ggtgttgaac gggccgaaaa
    19921 aacacgccaa aggctacatc gaaggtctgg aaatgctggc ttcaatgcgc ctgtgtgcta
    19981 acgttcctgc gcaacacgcc attcagaccg cgctgggcgg ttatcagagc atcagtgaat
    20041 ttattacccc tggcggtcgt ctttatgagc agcgtaaccg cgcatgggaa ttgatcaatg
    20101 atattccggg cgtttcctgc gtgaaaccgc gcggtgcgct gtacatgttc ccgaaaatcg
    20161 acgccaggcg ctttaacatt cacgacgatc agaaaatggt gctggatttc ctgttgcagg
    20221 aaaaagttct gttggtgcaa gggacggcat tcaactggcc gtggccggat cacttccgca
    20281 ttgtcacgct accgcgtgtc gatgatatcg agctgtcttt gagtaagttc gcgcgtttcc
    20341 tttctggtta tcatcagctg taatcttaat ttcactgccg gagattgcat ccggcagtgt
    20401 tatcccgcca caatgacctg atgatgtcat catacgtaag gtcactatga aacagagcca
    20461 tttttttgcc catctctccc gcctgaaact cattaaccgc tggccgctaa tgcgcaacgt
    20521 gcggacggaa aatgtgtccg aacacagttt gcaggtagcg atggtcgccc atgcgctggc
    20581 tgctatcaaa aatcggaaat ttggcggtaa tgtcaacgcc gaacgtatcg ctttactggc
    20641 gatgtaccac gatgcctcag aagtgctcac cggcgatctc cctactccgg tgaaatactt
    20701 caatgcgcaa atcgctcagg agtacaaggc gattgaaaaa atcgctcagc aaaaactggt
    20761 cgatatggtt ccggaagagc tgcgggatat ctttgcgccg ttaattgacg agcatgcata
    20821 tagcgatgaa gaaaaatcgc tggtgaaaca ggcagatgca ctgtgtgcat atctgaaatg
    20881 tctggaagaa ctcgcggcgg gaaataatga attcttgctg gcaaaaacgc gactggaagc
    20941 gacgcttgaa gcgcgccgca gccaggagat ggactacttc atggaagtct ttgttcccag
    21001 cttccatctt tcgctcgatg agattagcca ggattcaccg ctgtaagcag ctggagtctg
    21061 cgtcgcatca ggcaataagc gccggatgcg acatcagcct cttgtcaaaa cggaaacagc
    21121 atcgggatca tcaccacaca aaccgccatc acgataatgg tgaacggtac ccccaacttc
    21181 acaaagtcac tgaagctgta atttcccgga cctaaaacca gtgtgttaac aggtgaagaa
    21241 accggcgtca taaaggcggc ggatgctgcc atcgccacga ccatcgcgaa tgggtaaggc
    21301 gacacaccca tcgttttggc agcagccagc gcaatcggag ccatcaacac cgccgtcgcg
    21361 gtattagaga taaacagccc aataaccgcc gacaggacaa acaaacaacc cagcatcata
    21421 tgtggcccgt aaccgccgcc aatgtccatc agccctttca ccgccagcgc gacacctccc
    21481 gttttctgta atgccacagc aaacggcatc atcccaacga tcaaaataat gctcggccag
    21541 tgaatggatt tataggcgct ttcagcatcg atacagcgga atttccccat cagcaggcag
    21601 gcgatgatag cggcaacagg attagggatt tcatcggtaa gcattaacgc caccatcaac
    21661 accaggcaaa aaatggcatg aggtgcctga ctgtgtgctg gcgatgcttc actcacttct
    21721 tctggtaagt tcagcgccac aaagtcacgc ccctgttttg ccagcatacc gatcagtttc
    21781 cagttaccca caaccaggat gatatcgccc agcagcagag gctcatccgc cagcgaacct
    21841 tccatcgcct cgccattgcg ctttagcccc accacattca gtccgtagcg ggtacgaaaa
    21901 ccaatttcgc gcaccgattt accaataagt tcagactcag gaattaatga aatctctgcc
    21961 atgcccacat caagggcctg gtcagaaaaa tactcgccgc gcagtaccat cggctccagc
    22021 aattgctcac tacaaaattg ccggagatcg acatcagccg cagacatatc aataagcaaa
    22081 acgtcacgcg cgcgaaattc agaaacccca ttaacgttca cgataacgcg acgaaaacgc
    22141 cgccagcgtt caacaccgat gacgttagcg ccataacgct cacgtaattt gagatcgtcc
    22201 agccgttgac caatcattgg cgaaccgggg cgaatagcca gacgacgcgc acgcccggtc
    22261 agtcgatatt cacggataag atcgcgaaag gttcgacgcg tccagccttc gcgctgcggg
    22321 gtctgggtat cccctttcag catgaaacgc atcactaaca tatacaaaat acccagcacc
    22381 agcacgacca ggccaatagg tgttacgcta aagaaactaa aaccatgata gccttcacgc
    22441 agcaattcac tgttgactac caggttcggc ggcgtcgcca ccagcgtcat catgccgctt
    22501 atcagcccgg caaaacttaa cggcatcatc aggcgcgacg gcgacgtttg catacgcatg
    22561 gcaacgctta acaccacggg aataaagata gcgacaacgc cggttgaact cataaacgcg
    22621 ccaagccccg cgacggtcag catcaacaaa accaacattt tgatttcact gttgcccgcc
    22681 actttgacca gccatgtccc cattacagtg gcaacaccgg tacggaccaa accatcgcca
    22741 ataatgaaca aggcggcaat caggacaacg ttaggatcgg aaaagccgga aaatacttcg
    22801 gggaccgtca gcgttccgct taatgcaaac gcgacaataa caaacaaagc gaccgcatcc
    22861 atacgcactc tgcccgtcgc aaacaagacg atggcaacgg ccagtaatga aagaacccaa
    22921 atcaattcac cgttcacaac ttatccttgt taattgaggg ggatgacttg attctgccat
    22981 aaaaaagccc cgacgagacg gggctaaatc atgatcaggt gtttcactga ataataacat
    23041 cgccatttgg ctgtttggtc acagtaattt gctccagact gtggaggacc aaatcgacct
    23101 cattcaggcg cggggtatct gccggagcgt taaccgcaat gacatggcaa cccgccgcca
    23161 ggccagaaag cacgccagcg ggagcatctt ccaccactac acactcctgc ggcgcaagcc
    23221 ccagcagctg cgcgcctagc agatacgcat caggttctgg ttttccgcgc ttcactcgct
    23281 cagcggtcac aaacacctct ggcgcgggaa gcccagctat tttatggcgc gctcgcgcta
    23341 ccggcatgga gccagaagtc acaatggccc acggaatacc tgctttattc aaatgattga
    23401 gtaaggcgat tgcccccgga agcgcggtaa taccctcggt ttccgtggcc tcgatttgct
    23461 ccagacgcgt aaactcggcg gcaatatcag cctcggattt gcccgccata aaatggcgca
    23521 gagaggtgat cgcctgttta ccgtgaatga aagccagcac ctcttccggc gctaacccat
    23581 gacgtctggc ccagttgctc cacgcccgct ctaccgcagg cagggaatcc accagcgttc
    23641 catcaagatc aaacagaaaa cctttgcacc gcacgcgggc ctcctcaggc gttgataatt
    23701 tgattaattt cgttggcgct caaatggtac tgacgcgggc aggcatgcca cacattaagc
    23761 atgcgctgat atttttccca cattggcgtc tgggcgttaa aaccgtgagt tccggcgtca
    23821 aaatgggtat agcgcccttc aacattaacc ataaagcgga cataaccgag gtaacgtgct
    23881 tcagtggcgg cgtcaaagcc gaggaaggtg acacgacgtt catcgatgga ttgctggtcc
    23941 tgcaaattag accaggaaac atgcaacgca tgatacatct ccataatgtc gatgatagtg
    24001 cggcaggttt cttctttcag ctcgccaaac tcgcgatcca gttcacgcat ctgtaatcca
    24061 taaccacgct caatgattgt ttgcaggcga cggtaacgtt cagcatttgc cggatcgagc
    24121 atagtcatca tcttgtactg gttagacaaa ataagacgtt gcgcgttggt catttccatt
    24181 gttgactcct gtatcactct actacggtga aaaaaaaaga aggctgagta tgccttcttt
    24241 tatatgcgta atcaggggtc aattacaaat catcaaggaa agttttatcc agttgtttga
    24301 aggcgcgctt aagcgtgtca gctaatgcct ggtaatcagg cttgccttca acgggtgcca
    24361 acacctgtcc agactcctgt aatttaccgc gaacttcata aaaccagttg aggatagcag
    24421 ggggtaatgg cgttacagaa cgcttgccca gccaccacaa tccctgcatg ggtaaactta
    24481 aagcgaacag cgcagtggca actgccggcc caagctgacc gcccagggca atctgccagc
    24541 agagagtaaa tacggcgatc ggcggcataa aacggatcgc ataacgcgtc atcttgataa
    24601 cgcgattttc gacaaagacc ggggcaaggc gtttttccag cggccacgtc tttgagtaat
    24661 gctgtccccg gcgaaacaag ctaaaaaaat taacagaacg attatccggc gttgacatgc
    24721 ttcacctcaa cttcacatat aaagattcaa aaatttgtgc aaattcacaa ctcagcggga
    24781 caacgttcaa aacattttgt cttccatacc cactatcagg tatcctttag cagcctgaag
    24841 gcctaagtag tacatattca ttgagtcgtc aaattcatat acattatgcc attggctgaa
    24901 aattacgcaa aatggcatag actcaagata tttcttccat catgcaaaaa aaatttgcag
    24961 tgcatgatgt taatcataaa tgtcggtgtc atcatgcgct acgctctatg gctccctgac
    25021 gtttttttag ccacgtatca attataggta cttccatgtc gagtaagtta gtactggttc
    25081 tgaactgcgg tagttcttca ctgaaatttg caatcatcga tgcagtaaat ggtgaagagt
    25141 acctttctgg tttagccgaa tgtttccacc tgcccgaagc acgtatcaaa tggaaaatgg
    25201 acggcaataa acaggaagcg gctttaggtg caggcgccgc tcacagcgaa gcgctcaact
    25261 ttatcgttaa tactattctg gcacaaaaac cagaactgtc tgcgcagttg actgctatcg
    25321 gtcaccgtat cgtacacggc ggcgaaaagt ataccagctc cgtagtgatc gatgagtctg
    25381 ttattcaggg tatcaaagat gcagcttctt ttgcaccgct gcacaacccg gctcacctga
    25441 tcggtatcga agaagctctg aaatctttcc cacagctgaa agacaaaaac gttgctgtat
    25501 ttgacaccgc gttccaccag actatgccgg aagagtctta cctctacgcc ctgccgtaca
    25561 acctgtacaa agagcacggc atccgtcgtt acggcgcgca cggcaccagc cacttctatg
    25621 taacccagga agcggcaaaa atgctgaaca aaccggtaga agaactgaac atcatcacct
    25681 gccacctggg caacggtggt tccgtttctg ctatccgcaa cggtaaatgc gttgacacct
    25741 ctatgggcct gaccccgctg gaaggtctgg tcatgggtac ccgttctggt gatatcgatc
    25801 cggcgatcat cttccacctg cacgacaccc tgggcatgag cgttgacgca atcaacaaac
    25861 tgctgaccaa agagtctggc ctgctgggtc tgaccgaagt gaccagcgac tgccgctatg
    25921 ttgaagacaa ctacgcgacg aaagaagacg cgaagcgcgc aatggacgtt tactgccacc
    25981 gcctggcgaa atacatcggt gcctacactg cgctgatgga tggtcgtctg gacgctgttg
    26041 tattcaccgg tggtatcggt gaaaatgccg cgatggttcg tgaactgtct ctgggcaaac
    26101 tgggcgtgct gggctttgaa gttgatcatg aacgcaacct ggctgcacgt ttcggcaaat
    26161 ctggtttcat caacaaagaa ggtacccgtc ctgcggtggt tatcccaacc aacgaagaac
    26221 tggttatcgc gcaagacgcg agccgcctga ctgcctgatt tcacaccgcc agctcagctg
    26281 gcggtgctgt tttgtaaccc gccaaatcgg cggtaacgaa agaggataaa ccgtgtcccg
    26341 tattattatg ctgatcccta ccggaaccag cgtcggtctg accagcgtca gccttggcgt
    26401 gatccgtgca atggaacgca aaggcgttcg tctgagcgtt ttcaaaccta tcgctcagcc
    26461 gcgtaccggt ggcgatgcgc ccgatcagac tacgactatc gtgcgtgcga actcttccac
    26521 cacgacggcc gctgaaccgc tgaaaatgag ctacgttgaa ggtctgcttt ccagcaatca
    26581 gaaagatgtg ctgatggaag agatcgtcgc gaactaccac gctaacacca aagacgctga
    26641 agtcgttctg gttgaaggtc tggtcccgac acgtaaacac cagtttgccc agtctctgaa
    26701 ctacgaaatc gctaaaacgc tgaatgcgga aatcgtcttc gttatgtctc agggcactga
    26761 tactccggaa cagttgaaag agcgtatcga actgactcgc aacagcttcg gcggtgcaaa
    26821 aaacaccaat attaccggcg ttatcgttaa caaactgaac gctccggttg atgagcaggg
    26881 tcgtacccgt ccggatctgt ccgagatttt tgacgactcc accaaagcaa aagtgaacaa
    26941 cgttgatccg gcgaagctgc aagaatccag cccgctgccg gttctcggcg ctgtgccgtg
    27001 gagctttgac ctgatcgcga ctcgtgcgat cgatatggct cgccacctga atgcgaccat
    27061 catcaacgaa ggcgacatca atactcgccg cgttaaatcc gtcactttct gcgcacgcag
    27121 cattccgcac atgctggagc acttccgtgc cggttctctg ctggtgactt ccgcagaccg
    27181 ccctgacgtg ctggttgccg cttgcctggc tgccatgaac ggcgtagaaa tcggtgccct
    27241 gctgctgact ggcggctacg aaatggacgc gcgcatttct aaactgtgcg aacgtgcttt
    27301 cgctactggc ctgccggtat ttatggtgaa caccaacacc tggcagacct ctctgagcct
    27361 gcagagcttc aacctggaag ttccggttga cgatcatgag cgtatcgaga aagttcagga
    27421 atacgtggct aactacatca acgctgactg gatcgattct ctgactgcca cttctgagcg
    27481 cagccgtcgt ctgtctccgc cagcgttccg ttatcagctg actgaacttg cgcgcaaagc
    27541 gggcaaacgt atcgttctgc cggaaggtga cgaaccgcgt accgttaaag cagccgctat
    27601 ctgtgctgaa cgtggtatcg caacttgcgt actgctgggt aatccggcag agatcaaccg
    27661 tgttgcagcc tctcagggtg tagaactggg tgcaggcatt gaaatcgttg atccagaagt
    27721 ggttcgcgaa aactatgttg gtcgtctggt cgaactgcgt aagaacaaag gcatgaccga
    27781 aaccgttgcc cgcgaacagc tggaagacaa cgtggttctc ggtacgctga tgctggaaca
    27841 agatgaagtt gatggtctgg tttccggtgc tgttcacacc accgcaaaca ccatccgtcc
    27901 gccgctgcag ctgatcaaaa ctgcaccggg cagttccctg gtatcttccg tgttcttcat
    27961 gctgttgccg gaacaggttt acgtttacgg tgactgtgcg atcaacccgg atccgactgc
    28021 agaacagctg gcagaaatcg cgattcagtc cgctgattcc gctgcggcct tcggtatcga
    28081 accgcgcgtt gctatgctct cctactccac cggtacttct ggtgctggta gcgacgtaga
    28141 aaaagttcgc gaagcaactc gtctggcgca ggaaaaacgt cctgacctga tgatcgacgg
    28201 tccgctgcag tacgacgctg cggtaatggc tgacgttgcg aaatccaaag cgccgaactc
    28261 tccggttgca ggtcgcgcta ccgtgttcat cttcccggat ctgaacaccg gtaacaccac
    28321 ctacaaagcg gtacagcgtt ctgccgatct gatctccatc gggccgatgc tgcagggtat
    28381 gcgcaagccg gttaacgacc tgtcccgtgg cgcactggtt gatgatatcg tctacaccat
    28441 cgcgctgact gcgattcagt ctgcacagca gcagtaatct cgtcatcatc cgcagctttg
    28501 cgctgcggat atcggaaccg gaaatagtca ctatttccgg ttttttattc tcttaatttg
    28561 cattaatcct ttctgattat cttgcttaac tgcgctgcat caatgaattg cgccatctca
    28621 ctttgcatac ttaccacttt gttttgtgca agggaatatt tgcgctatgt ccgcaatcac
    28681 tgaatctaaa ccaacaagaa gatgggcaat gcccgatacg ttggtgatta tcttttttgt
    28741 tgccatttta accagccttg ccacctgggt agttccggtg ggcatgtttg acagtcagga
    28801 agtgcagtat caggttgatg gtcaaacaaa aacacgcaaa gtcgtagatc cacactcatt
    28861 ccgcattctg actaacgaag caggcgaacc tgagtatcac cgcgtacaac tgttcacgac
    28921 gggcgatgaa cgcccgggtc tgatgaactt cccgtttgaa gggttaacct caggatcgaa
    28981 atacgggaca gccgttggca tcatcatgtt tatgctggtg attggcggcg cgtttggcat
    29041 tgtgatgcgt acaggaacca ttgataacgg tatcctggcg cttattcgcc atactcgcgg
    29101 gaatgaaatt ctctttattc ctgcgctgtt tattctgttt tcacttggcg gtgcggtatt
    29161 tggtatgggg gaagaggccg tcgcctttgc cattatcatc gcaccgctaa tggtccggct
    29221 gggctatgac agtattacca ccgtcctggt gacttatatt gccacgcaaa tcggttttgc
    29281 cagttcgtgg atgaacccgt tttgtgtggt cgttgctcag gggattgccg gcgttccggt
    29341 gctttctggc tccgggttgc gcatcgtggt atgggttatc gccactctga ttggcctgat
    29401 ctttaccatg gtgtacgcct cacgagtgaa aaagaatcct cttctgtcat gcgtgcatga
    29461 gtccgaccgc ttctttcgtg aaaagcaggc ggatgttgaa caacgtccgt ttacctttgg
    29521 tgactggctg gtattgattg tcctgaccgc cgtaatggtc tgggtgattt ggggcgtgat
    29581 cgttaatgcc tggtttattc cagaaattgc cagccagttc ttcaccatgg gtctggtgat
    29641 tggcatcatc ggcgtcgttt tccgccttaa cggcatgacg gttaatacca tggcttcatc
    29701 ctttaccgaa ggggcgcgaa tgatgatcgc ccctgccctg ctggtgggtt tcgccaaagg
    29761 gattttgctg ctggtcggta atggtgaagc gggtgatgcc agcgtgttaa ataccatcct
    29821 caacagcatt gccaatgcca ttagcggtct ggataacgcg gtcgcggcct ggtttatgtt
    29881 gctcttccag gcagtattta atttcttcgt gacgtccggt tctggtcagg cggcgttaac
    29941 catgccgtta ctggcaccgc ttggcgatct ggtcggtgtt aaccgtcagg ttaccgtgct
    30001 ggcgttccag tttggtgatg gcttcagcca catcatttac ccgacctcag cttcgttaat
    30061 ggcaacgctc ggtgtttgcc gggtggactt ccgtaactgg ctgaaggtgg gcgcgacact
    30121 gcttggactg ctgtttatta tgtccagcgt cgtggtgatc ggcgctcagt tgatgggcta
    30181 ccactaaaaa tgttaagagc cgcaattgcg gctctttttt tcattctgcc gtttcagtct
    30241 ctacggcttc atttttggca ttgcgcttca tccacaacgc cagcgctttc agcgagtctg
    30301 gagtgaactc atcgcagcgt gcggtgattt cttccggcgt cagccagcaa acttcactga
    30361 cttcatcttc ctgtagggcg aagggaccgt gagagacgca actgaacaac gcgccccaga
    30421 cacggcaatt tttatcttcg aaatagaact gcccgtgctc ggcaaagggg acaccggcaa
    30481 tgcccaactc ttcttccgct tcgcgacgcg cggattccag cagttgctca tcggcctgga
    30541 ccacaccgcc tgcggtcgca tctaacatgc cgggtaaaaa gtcttttgtc tcggtacgac
    30601 gctggaccag aattttgccc atgccatcat gcacgacgat gtaagttgca cgatgacgca
    30661 gacactgtgc ccgcatttgt tcccggctgg cttgtgcaat gacttcgttc tcttcattga
    30721 caatatccac ccattcagta cttgccaaac gacgctgttc cattatcagg aaaccttctt
    30781 tttctggcgc tcttacggcg cattttgagt tgtgggtaaa ttacggatta atcgcgacct
    30841 gcgcaatgat actttgatca ttgagtgcga ttacactaag tacgtcatta tccagcatgc
    30901 cataactcgc cggattaccg cctttaggaa tactcaccga gccggggttg aagtggaaaa
    30961 tctccccccg ctgttctgcc actggcagat gggtatgacc gtacaccagc acatcgttct
    31021 ggtttaaagc aggtaggttt tccgggccaa aaagatgacc atgcgtcaaa aacagacgtt
    31081 gtttttccag taatacctgt tgccacggcg cggttatcgg gaaatgcagc agcatttgat
    31141 ccacttcgct gtcgcagttg ccgcgcacag cgataacctt atgtgccact tcattaagcc
    31201 gttcagcgac tttggctggc gcgtaaccct ccggtaaagc attacgcggg ccgtgattca
    31261 acacgtcgcc aaggatcacc agccactggg caccgctttg ggcaaacaac tccagaacac
    31321 gttccgtcgc cggtaacgac ccatgaatgt ccgatgcaaa catcagtttc atcactcact
    31381 cctcgtcgaa aaaacgtaag ctatgatact ggattctttc gttgctatca gccagattgc
    31441 ttcgccgaaa gagcaataaa acgctggaca gacgctcgct gccactggaa tgtcgcataa
    31501 tccaccaggc gttccggcac ctcatcgcca tgtagtacca ggcggttaat cattagcgcc
    31561 agatcagtat cagcaatgca ccattcacca aataaattcg gccgccccag tgctaacaaa
    31621 tgttctgcca tcgcgaacag tttctctgca ctggcttttc cctcggccgt tagtggcgct
    31681 tttttcgccc ccgcaaagac aacatccgtc ggacgctctt cgcggatggg catcagatcg
    31741 ctgcgcaacc aggcctgaat ctgtcgtgca cgcgcacgat tttctaaatc aagcggataa
    31801 atacgttccc aggtcggtgg cgcaaatcga tcttccagat actccgcaat ggcagaagat
    31861 tcactcaact caaaatcatc gatttgtaat aacggcacac ggcgtgtctg accgtaacct
    31921 tgccacgtcg gttgcaaatg ttcaccgctg tcgaggtcga tggtcttgat atgaaacgac
    31981 aggcctttct cctgcaacgc cacccaggcg gataacacat aaggggagaa aaaatgggca
    32041 tctgaccaaa gcgtgatagc gggtttactc attatgtcct cggcaataaa gggggctggc
    32101 tatcaaacta tagagccttt ttgtcactgt cacgtgacga atactcacgc aagtcgccgc
    32161 gctttctata cttgtggtgt tcagatgatt agacaaccgg agctgcaatg atcgatctct
    32221 atttcgcccc gacacccaat ggccacaaaa ttacgctgtt tctcgaagaa gcagggctgg
    32281 attatcgctt gataaaggta gacctgggga aaggcggtca gtttcgcccg gaatttttgc
    32341 gcatttcgcc taacaacaaa attccggcaa ttgttgatca ttctccagcc gatggcggcg
    32401 aaccgctaag cctctttgaa tctggtgcca ttttgttgta tctggctgag aaaacggggc
    32461 tctttttgag tcatgaaacg cgtgaacgcg ccgccacatt acagtggtta ttctggcagg
    32521 taggcggact ggggccgatg cttgggcaaa atcatcattt taatcacgca gccccccaaa
    32581 ccattcctta cgctattgaa cgttatcagg ttgaaactca gcgtctgtac catgtactga
    32641 acaagcggct ggaaaactcg ccctggctgg gaggcgagaa ctacagcatt gcggatattg
    32701 cctgctggcc gtgggttaat gcctggactc gccagcgaat tgacctcgca atgtatccgg
    32761 cagtcaagaa ctggcatgag cggatccgtt cgcgccctgc caccgggcag gcactgctaa
    32821 aagcacaaca cggtgacgat cgttcggata gttaacagaa acaggttctc gtgtattatt
    32881 tcatcctaag taaaacaacg gagaacctgc aatggcacaa cctgccgcta ttattcgtat
    32941 aaagaacctt cgtttacgta cgtttatcgg aattaaggaa gaagaaatta acaaccgtca
    33001 ggatattgtt atcaatgtga cgatccacta ccccgccgat aaagcgcgca ctagcgaaga
    33061 tatcaacgat gcgctgaatt atcgcaccgt aacgaaaaac attattcagc atgtagagaa
    33121 taaccgtttc tctttgctgg aaaaattaac tcaggatgtg ctcgatatcg cacgtgaaca
    33181 tcactgggtg acgtatgctg aagtagagat cgataaactg cacgcgctgc gctacgccga
    33241 ttcggtatcc atgaccttaa gctggcagcg ttaaccgcca tatcgggagg ctgcatgaag
    33301 atagtgatca ccggagggac gggattaatt ggtcgccatt tgattccgcg tttgctggat
    33361 ctgggccatc aaatcacggt agtgacgcgt aacccgcaga aagccagttc cgttctcggc
    33421 cctcgggtga cactatggca agggcttgcc gatcaaagta acctcaacgg cgttgatgcg
    33481 gtaatcaacc tggccggaga accgattgct gataaacgct ggactcacga gcaaaaagag
    33541 cgtctctgcc aaagccgctg gaatatcacg caaaaactgg tcgatttgat taatgccagc
    33601 gacacgccac cgtcggtact catttccggc tcggcaacgg gctattatgg cgacttaggt
    33661 gaagtggtgg ttaccgaaga ggaaccgccg cataacgaat ttacccataa actctgcgcc
    33721 cgctgggaag aaattgcctg tcgggcacaa agtgacaaaa cgcgagtgtg cctgctgcgt
    33781 accggcgtag tgctggcacc ggatggcggt attctcggta aaatgctgcc gccgtttcgt
    33841 cttggcctgg gcgggccgat tggttccggt cggcagtatc tggcctggat tcatattgat
    33901 gatatggtca acggcattct ctggctgctg gataacgagc tgcgcgggcc atttaatatg
    33961 gtttcgccct acccggtacg caatgaacaa tttgcccatg cgctcggtca tgcgctgcat
    34021 cgcccggcta ttttgcgcgt ccccgcaacc gccattcggc tgttaatggg cgaatcttca
    34081 gtactggtat taggtggaca acgcgcgctg cctaaacggc tggaagaagc gggttttgcg
    34141 tttcgttggt acgatttaga agaggcgctg gcggatgttg ttcgctgatg tggtttactg
    34201 caaacatccg ccagttaact cccggtgtta caggattagt ggctttgcgc gataagatcg
    34261 tctggtgaaa gtcgggtcac catcataact aactctctgt ctaaacctct ctccagcatt
    34321 tcctgagcaa tgcgcagggc ttcttcgcgt ttgccctgca ttgcgccttc ttcacgtaat
    34381 ctgtcagcaa tggtcatcag tttctccttt tcttgtggtg cgcgttccgc tatctcacca
    34441 ataaatgcac ggaaacgctg ggcatccccc gtttgtaata cataattaaa cagggctttt
    34501 agctgtctgt cattagtgtt ccctgtaact agcagcgaaa caatttggtc gactaatccc
    34561 aacagatcgc gctgacgaat atgtttctga attaactcca acagcgccat tttgcgatgt
    34621 tgcataatct cgtcatccgg caccacggta atatccacaa gcggaaaagc cgatgaatat
    34681 attttgcggg ctatagcagg ctcggcaaat tcatcaagcc agcagagtga ataaggataa
    34741 ggacttctgc aaccatgata aaatagcatc gggatcacca atggaagctc tttatagccc
    34801 gcatcaagat ggttttgcat cgctgcaatg gaatagcgca tcatgcgaaa agccattaat
    34861 tcttccggct tactttggtg ctctatcacc acataaatat aacctgctcc ctcctgcgtt
    34921 ttcacagacc acaagaggtc ggaataatat tgccgcaggt cttcatcaat aaaactgttt
    34981 ggttccagtt taagcgtcgt taaatcacac agtttgcgca gcggcgcggg aagatgaata
    35041 tcaataaaat cccgcgcggt gtctggatgg cgtaaaaaag atttaaatac cgcatcatgc
    35101 ggcgtggaag ttgtcgatat tgtcatggcg ttccgtcacc cctcaaattt aagatgacgc
    35161 gacaataacc acgattaaca cccaatgcag caggcagttt ttatctttgg acagcgaatt
    35221 cagaagtatt tttagcgggc tgcaactttt acatttcagc ggaagcggac tcgcaaattt
    35281 cccttgaaaa tactccggca gcgttagcta ccggaggggg aattatttca gcgatccctt
    35341 aaggaactgt tgcagacgag ggctttgcgg gttgccaaat aactgctccg gcgcgccttc
    35401 ttcctctatt ttcccctgat ggagaaaaat gacgtgagta gaaacatggc gagcaaagcc
    35461 catttcgtgg gtcaccacca ccatggtttt cccctcttct gccagttgct gcataatacg
    35521 caacacttcg cctaccagtt caggatcgag cgccgaggta ggttcatcaa acagtaaaac
    35581 ttccggttcc attgccagcg cccttgcgat ggaaacacgc tgttgctgac cgccggaaag
    35641 atgcaccgga tatttcccct gcgcacgttc gtctatcccg actttcgcca gatacttcac
    35701 cgcccgctcg cgcgcttcct gcttgctcag gcccaacacc tgaatcggcg cttccatgac
    35761 gttttccagc accgtcatat ggctccagag attgaagtgc tggaatacca tcgtcaggcg
    35821 tgtgcgcagt aagcgcagct gatttttatc ggcgactttg agttgaccat ctttgtcgcg
    35881 caccagattg atcgtctggc cattgaccac gatcgatcct tcgctcggtt tttcgaggaa
    35941 gttaatgcag cgcagaaagg tacttttccc cgatcccgac gatccgatga tacttatgac
    36001 atctccggca ttcgcttgca atgagacccc tttcagcact tcgtgttcgc cgtagcgttt
    36061 gtgcaaatcg ataacgttta atttattctc ggacatcgta ttctcagtgc gttgaagaag
    36121 gtttcacatg ctgcaaccag cgtttttcag ctctgcgaaa gaggctgatc aggacataag
    36181 agatgattaa atagagcacc gcggcaatgc cgaaggcggt aaaaggttga tatgtggcgg
    36241 cgttaatatc gcgggcaatt ttcagcagat ccggcaccgt ggcagtaaat gccagcgcag
    36301 tagagtgcag catcaggatc acttcgttgc tgtatgccgg taacgcaata cgcagcgcag
    36361 aaggcaaaat aatgcagcga tacattttaa aggtcgagaa gccataggct ctggcggctt
    36421 caatttcccc atgcggcact gaacggattg ccccggcaaa aatctcggta gtgtaagcgc
    36481 aggtgttaag cgtcagcgcc agcacggtac agttcagacc actgcgaaaa aaggcgttaa
    36541 ggaactcggt tcccttaaca atctccagcg tgtacatgcc ggaatagaac accagcaact
    36601 gaacatacag cggcgtaccg cgaaaaatat aggtaaataa ccagattgga aactggatgt
    36661 atttattact tgagacgcga ccaatcgcca gaaacagcgc cagaactccg cctatcacta
    36721 ccgacaaaat cagcagccac agggtgatcg ccacgccagt aaagcgataa ccgtcagtcc
    36781 acagcagtgg tttccagtat tcatgtaaga tttcgatcac aggtcagccc tcttcacacc
    36841 cacggagtag cggcgttcaa ggaacagcag cacaccattg gaaacggtgg tgaaaacaag
    36901 ataaatcacg ccacagacga tagcgaaata gaacggttcc caggtacttt tgcctgccag
    36961 ctgcgtggct ttgaccacat cttccaggcc gagtaacgaa accagtgcgg tagatttgag
    37021 gatcacctgc cagttgttgc caatgcctgg cagggcgtaa cgcatcatcg ccggaaacat
    37081 gatccgccga aacacttgcc cacgagtaaa accgaacgcc gtcgccgcct ctatatgtcc
    37141 tttcggcact gccataaaag caccacggaa cgtttcggta aaataagcac cgtagataaa
    37201 accgagagta ataataccag cgaccatcgg atcgatatca atctgcccga cgcccatcgc
    37261 ctccgtcacc gtgtttagtg caatctgcaa accgtagaaa attagcagca tcaacaccaa
    37321 gtccggcacg cctcgaatca gcgtggtgta cccttcgaaa atcagccccg aaagccgatt
    37381 ttgcgagagc ttaccgccag cgccaattaa accgatgatt acagcgagca ctacagagct
    37441 gatagccagc tccagcgtga cgagcgcacc ctgtaaaata acacctgaaa acccatacaa
    37501 catgctgcct gtcctgtcgt gtgtggtgaa ttaccgcctc ttgtctccct ccggttaccc
    37561 gaagggagcg ggctttcttt caccgatggc gattaaccac cataaacatc aaaatcgaag
    37621 tactttttcg ctaatttctc gtaagtaccg tcagcgcgca tttcggcaaa ggctttgttc
    37681 agtgcctcgc gcagttcgtt atcttcttta cgcaggccca tgccggtccc tacgccaaac
    37741 agtttttcat ctttaacaga cgggccaccg aatttgtaat ctttaccgac gggttgtttg
    37801 aggaaacctt cgctggctgc gacctcatcc tggaacgcgg catcaatacg tccggcagtc
    37861 aggtcagaat aaatattgtc ctgcccctga taagaaacga tttcaatgcc ttttggtgcc
    37921 cagtgttcgt taccgaacgt ctcctgggtg gtgccctgca atacgcctac ccgtttgcct
    37981 ttcagcgatt cgactgtcgg ctgaatgtcg gaatttttcg ccaccaccag acgagaatcg
    38041 gcagcgtaca gtttgtcggt gaaggctatt tcttgctgac gtttttccgt aatggaaagc
    38101 gatgacatga tggcgtcaat cttcttcgct tttaaggacg ggattaacgc atccagtggg
    38161 ttttcgacaa acgtacattg cgtattgatg cgtttgcaca actccttcgc cagatcgata
    38221 tcgaagccaa ccagttcacc ttgtgaattt tttgattcaa atggcgcata ggtcggatcg
    38281 gtaccgatgc ggatgttttg cggaatcgca gcaaacgccg cagttgcgct ggagaaggcc
    38341 agaaccagag agagcgatag caccagtttt ttcataatgt cctcaactga cagtcttttt
    38401 atagggaata tttacaggtt tgttacactt atcgtgccat aaaattgacc atcaaggcaa
    38461 aatatcccgc cccgttagac gtattatttt tcattaaaaa tgcttaagta tgcatttcaa
    38521 tgcaccacga tagtgcaaca aacctggcgt gcaccatgat gatcattcca tcaggtacag
    38581 cttccctgcg acgtatcagt caccgtagac attaaagtcg aaatactttt tcgccatctt
    38641 gtcgtaggtg ccgtcctgac gcagctcgtt aagcgcctta ttgaaggccg ccgtcagttc
    38701 agcatcatct ttacgcagcc ctacaccggt gccgtcaccg aagtattttt tgtctttcac
    38761 tgatgggcct gcaaaggcga aatctttacc ggcgggttgc ttaaggaaac cttcgctggc
    38821 agcaacctca tcttgtaacg cagcatccag gcgtcctgca gccagatcgg aatagaccaa
    38881 atcctggtta gcataggcca ccacatcgac ccccttactg cgccagttat cattggcata
    38941 cgcttcctgg gttgatccct gcagcacacc aacatgttta cctttcagtg aatccagcgt
    39001 tggctgaatc ggtgaacctt tggcagcaat cagacgagag tctgcggcgt acagcttgtc
    39061 ggagaaagca atctcctgct gacgtttatc ggtaatggaa agcgacgaaa taatggcgtc
    39121 gatttttttc gctttcagtg aggggatcag cgcgtcaaag tcactggcaa cccaggtaca
    39181 tttcacctgc atccgtttgc acatctcgtt accgagatcg atatcaaagc caacaaagtc
    39241 acctttggca tctttcgatg agaacggcgc ataggtggta tcagttccga tacgtaccgt
    39301 ctccggtagc gccgcatagc tggaagccgc tgcggagaga ccgactaaca aagacagagc
    39361 gagaatcgac ttcttcatac ataaccctca agtgaaaatg gcttttttat gttgtgtatt
    39421 gtgttgtgtg tttgcaggct ctttcatgca ggtcttatgc catcttgacg acaacagtaa
    39481 cattcaacgt taaatatgtt aataagacgt tgcattattg tcctgaagtt gaagatagca
    39541 ggtatagcgg ttgaatcgca gcgtttcgat tgaatggcag aaacaaaatg tcgaggattt
    39601 gatcgcggtt gcaaaattgc cctgaaacag ggcaacagcg gagttatgcg ccctgccagc
    39661 gggcaaagag atcttcagga agcgttatgg cgaattgatc gagtacacgg ttaaccgtct
    39721 gatttatcac atcatcaagg gattgcgggc gatgataaaa cgccggaacg ggaggcataa
    39781 tcaccgcacc gatttctgct gcctgagtca ttaaacgcag atggcctaag tgcaatggtg
    39841 tttcacgtac gcagagcacc aacgggcgac gctctttcag cacaacatct gccgcacggg
    39901 tcagtaagcc atcagtatag ctatggacaa tgccggacag ggttttgatt gaacagggta
    39961 aaatcaccat ccccagtgtc tggaaagaac cggaagaaat gctggcagca atatcgcgcg
    40021 catcgtgcgt cacatcggct aatgcctgca cttcgcgcag ggaaaaatcc gtttcgaggg
    40081 ataaggtctg gcgcgcggcc tggctcatca ccaaatgcgt ttcaacatct gcgacatcgc
    40141 gcagaacctg taataagcgc acgccataaa tcgcgccgct ggcaccgctg atgcctacaa
    40201 tgagtcgttt cataaatagt tgccctgtca gacttgcagg cagactttgc aggatttcgg
    40261 cgggagttgc aagtcagggt gccagaccgg caccctgagc gaaggcatca tccttcgtta
    40321 tgcatttcga gattttccac ttcgttctga cgttgcacgg ctttggcgtc gtcattacgt
    40381 aacgtatcga ggaaatcgag gtagccctga tcaacatctt tggtgacgta gacgccgttg
    40441 aacaccgagc attcaaactg ctggatatcc gggttttcag cgcgaacggc ttcgatcaaa
    40501 tcgttcagat cctggaaaat caacccgtca gcaccgatga tctggcgaat ttcatctact
    40561 tcacgaccgt gagcgataag ctccgtagcg ctcggcatat cgataccgta aacgttcggg
    40621 aagcgaattt ccggtgccgc agaagcgagg tacactttct tcgctccggc ttcgcgtgcc
    40681 atctcgataa tctgctcaga agtggtgcca cggacgatgg agtcgtcgac cagcaggacg
    40741 tttttatcgc ggaactcggc gcggttggcg ttcagtttac ggcgcacgga cttacgacgc
    40801 agctgctgac ccggcatgat gaaggtgcgg ccaacatagc ggtttttaac gaagccctgg
    40861 cggtacggtt tgcccagaat acgcgcaatt tccagcgcga tatcacacga ggtttccgga
    40921 atagggatca ccacgtcgat atccagatct tcccattcgc gggcaatttt ctcgcccagt
    40981 ttggtgccca tattcacgcg cgcactgtaa acggaaattt tgtcgatgaa cgagtccggg
    41041 cgggcaaagt atacatactc aaacaggcac ggattgctga ccggattgtc agcacattga
    41101 cgggtaaaca actgcccttc ttcagtgatg taaatcgctt cgcccggcgc gacgtcacgc
    41161 aggaaatcaa agcccagcgt atcgagcgca acgctttcgg aagcgaccat atattctgtg
    41221 cggttctcgt caatatcacg ttttcccagt accagcggac gaatcccgtt aggatcgcgg
    41281 aaagcaacca taccgtggcc gatgatcatc gccacacagg catacgcgcc gcggattaag
    41341 cggtttgtag cagcgatggc ggcgaaaatg ttgtcggctt ccagcgggta gtggcggaag
    41401 ttgtccagtt cgctggcaaa gatattaagc agaatttccg agtcggaagt ggtgttgatg
    41461 tggcggcgtt tttcttcaaa cagtttttta cgcaactcgt gagcgttggt cagattgccg
    41521 ttgtgggcaa gcgtaatgcc atacggagag ttaacgtaaa acggctgcgc ttcagaggcg
    41581 ctggagctac cagccgtagg gtaacgcaca tgaccaatgc ccatattgcc ctgcaaacgc
    41641 tgcatatggc gagcttcaaa tacatcactc accagcccgt tcgctttacg caaacggaag
    41701 cagttattgg catctatggt gatgatgccg gcggcatcct gaccgcgatg ctgaagcacc
    41761 gttaaggcat cataaatcga ctggttaacc ggcataacac cggcgatacc gacaataccg
    41821 cacatacgtc tttttcctcg ttaagccaca tctcagagca cttacgctct gggcaagaaa
    41881 cttgacgagc tttgcagata atcaaaaaac catctgatga taaaactgaa ctgcgggatc
    41941 agctgtgatt tgctccagtc ttcgcttttc gacaccccgg taaaggagtc gagaaagaag
    42001 agaatggcag caacaatcaa cacaccgcgc aacgcaccga aacagacgcc caacacccga
    42061 tcggtgcctg acaaccccgt tttctccacc aactggccta tcacgaagtt cacgatagca
    42121 ccaacgatca gggtagcgat aaacagtacc gcgatggcaa tcccatttcg aaccagttcg
    42181 tcttcaaagc ccgtaaacca gactgacagg taagtgtagt aatgactggc aacaaagaaa
    42241 gcacaacccc atgtcaccag cgataacgct tcacgaacaa agccgcggat caggctaacc
    42301 agagaggaaa aagcaatcac cgcgattatg gcgtaatcaa tccagaccat atgtgtccca
    42361 cgattttacg ccctgtcatc ctgttcgggg cgcattctaa cagaaaaaga aaacgtttgc
    42421 gtagggattt ccttcccacg catcaataaa aatggcgctg aaaaaatatt caacgccatc
    42481 gactttttat gcctttgcgg catcgggcaa tgcgtgtcgg atgcggcgtg aacgccttat
    42541 ctgtaccaga taagacgcgt tagtatcgca tcaggcaaga ccatattaat tcggtgtata
    42601 acccattacc acgccgctta agccagaaag ttgcttcaac tcacccagcg aacctttcag
    42661 cttatctttc gaggcatccg gcccaaccag aatacgggta attttaccct gcactggcgt
    42721 ggatggcgac gtataaaccc gataaccggc accgcgcagc ttaccgacaa tctcattcac
    42781 tttatcggca tttttcagcg cccccagttg tacaacatag gctttacccg ttggcgctgc
    42841 tttttcttcc acgaccggct tcggcgcagg tggtgcttca accttcggtt tcggcggctc
    42901 caccggtttc ggcttcggtg gggcgaccgg tgcaggttcc ggttcaaact cggtgttatt
    42961 ggctgcaata gtggccggat cgagcgacgg tgctgcggca tcacctgccc gcacctcttc
    43021 cgctgcgcct tccggcggct gcgtcggcaa cgcctgagtg gcggctggca tcatatcagg
    43081 ctcatcgcga tcgcccgctt tcggcaccag cgggatagcc gcgaactcat cctgataatg
    43141 ttttttctgc ccgtccagca gccctggaag tactatcacc cccagcgcca ccagcacgat
    43201 cgtgcccact aaccgattct gaaacttact tgccaccgct tctcctcgcg tcaatcactt
    43261 ccatgacatg tgcgaccgtg tggaacgaac cacacaccag cacggtatct tccgctttag
    43321 cgtccgccat tgcggcatcc catgcctgcg ccacgctatc aaatgatttg ccgttaccca
    43381 aatgctcaag cagttgttct gccgtggcac cgcgcggccc ttccagtggc gcacaatacc
    43441 agtcatcaac cacgcttttc aaccaggcca gagttccggc aatatcttta tcatgtagca
    43501 taccgataac cgccagcacg cgcccgtttt tcggtagcgc tttcatacgc ccggtgagat
    43561 attccgccgc atgtggatta tgcgcgacat caaaaataac gcgtggcgac tcgctcacaa
    43621 tctggaaacg tcccggcaaa attgcgctgg caatcccgtc gcgaatggca ttttcactga
    43681 cctccagccc gctggcacgc agtgccgcca gcgccgttgc ggcattcggt tgtgggacaa
    43741 gcggcaacgg cagattttcc agcgtgccgt gagcatcgct aaacgtccag tcatgatcgg
    43801 tgacggaata gttccactca acgccccgac gttgtagcag tgcacctttt tcctgcgcca
    43861 catcagcaat ggtagaaggc atttccggct caccgacaat tgccggtttt tcgctgcgga
    43921 agatgcctgc tttctcgcga ccaatacttt cgcgatctgg ccccagccag tcggtatgat
    43981 ccagcgcaat gctggttact accgcgacat cggcatcgac aatattggtt gcgtccagac
    44041 gaccgcccag ccctacttcc agaatcacca cgtcaagttg tgcctgtttg aacagccaca
    44101 acgccgacag cgtaccgtac tcgaaatagg tcagggaaat atcaccgcgt gccgattcaa
    44161 tctccgcaaa agaggcggtg tgggccgatt ccggcaattc ctggccctgc acacgtacgc
    44221 gctcggtata acgcaccaga tgcggcgaac tgtagacgcc cacgttgtac cctgccgcca
    44281 tcagaatcga ctccagcgta cggcaggtgg tgcctttgcc attcgtgccc gcaacggtaa
    44341 acacaaatgg cgctggtttc agaacgccaa gacgcgccgc gacctggctc acgcgctcaa
    44401 ggccgagatc gatagtttta ctgtgcaggt tttccagata agaaagccac gaagccagag
    44461 gcgacgcggc ttgaggagtg cgtttgataa tcatggtatc cgctgattcg ttacggtgag
    44521 aatagcaaaa gggcagagcc agtggccctg cccttatcag ttatcaggcc tcaggttcct
    44581 gatctggtac cggtggcacc actacgcctt cacgcggcgc ttcaggattc ggcgctggca
    44641 gattcatcaa cttcgccaga atactcgcca gtttcaggcg catttccgga cgacggacga
    44701 tcatgtcgat cgcgcctttc tcgatcagga attcactgcg ctggaatcct ggcggcagtt
    44761 tttcgcgaac ggtctgttcg ataacacgcg gaccggcaaa gccgattaac gctttcggtt
    44821 cagcgatgtt gagatcgccc agcatggcga aacttgcaga aacaccaccc atggtcgggt
    44881 cggtcagcac ggagatgtac ggcaagccgc gctcctgcat ttttgccagc gccgcagagg
    44941 ttttcgccat ctgcatcagc gacatcagtg cttcctgcat acgtgcgcca ccagaggcgg
    45001 agaagcagat cagtgggcag ttatcttcca gcgcctgctc aacggcacgc acgaaacgtg
    45061 cacctaccac agaccccatg gaaccgccca taaaggcgaa ctcgaatgcc gcagcgacaa
    45121 ccggcattcc atacagggtg cctttcatca ccaccagcgc atctttttcg ccggtttctt
    45181 tctgcgcaga tgccagacgg tctttatact tcttggagtc acgaaacttc agcacatctt
    45241 tcggctcaag ctcgctaccc agctccacaa ggcttccttc atctaacagg ctatgcaggc
    45301 gattacgcgc tgtcatacgc atgtgatggt cacacttcgg acagacctca agattacgtt
    45361 ccagctcagc gcggtataaa acctgaccgc agctatcaca cttagtccac accccttcag
    45421 gaatgctcgc cttgcgggtg ggagtaatgt tgcttttaat tcgttcaatc cagctcatta
    45481 gggacctttc tgtctgaacc tggttcgatg ccagttttat ctttggggac gcataatgcc
    45541 atttttgccc ccaacagacc atgaatgttg cacattaaaa cataacagcc cgaaactttg
    45601 gataaaaaag tggtcgaacc gcggagttac tttttatttt gcggcgcgtg ccgcagcgcg
    45661 tttgtggcga ataaattcga aaacacctgg caatattgaa acaaaaataa tgccaacaat
    45721 catcagttta aggttgctct gaatgaaggg gagcgttccg aagaaataac ccgcgtaggt
    45781 aaaaatcagt acccatagca acgcgccgat gacgttaaaa gcggcgaaat gacggtacga
    45841 catgtggccc attcccgcaa caaacggcgc gaacgttctg acgatcggca caaaacgggc
    45901 gagaataatc gttttgccgc catgtttctc ataaaactga tgggttttgt cgagataact
    45961 gcgacgaaag attttcgaat ccggattact gaacagtttg tcaccaaata accgtccaat
    46021 ggtgtagttc accgcgtcac ccacaatcgc ggcgatcagc atcagcacca ccatcatatg
    46081 gacgttgaga tcgttggttt ccagtgatgc caacgcaccg gcaacaaaca gcaatgaatc
    46141 acccggtaaa aacggcgtta ccaccagacc ggtttcacag aacaaaatta agaacaaaat
    46201 ggcataaacc cagacgccat actccgcgac cagttctgcc agatgcacgt caatgtgcag
    46261 gataaaatcg atgaggaaat aaatcaggtc catatttgcc tatgccttgt actcgtcatc
    46321 tatcaggctg taactacgtt ggctacagcc tgaaatgttc cgagcattat tctcgttagt
    46381 ccgccagaaa tagcgggccc attggcggtt ttggaagatc ataccggtca gggtaatcca
    46441 ccgcgaccag atacagccct tccgcttttg ccgttgctgc cgccagcgtt ctgtcctttg
    46501 ccgctagcaa ctctgctatc cagctctccg gctggttgtg ggcaccgact tccatcaggc
    46561 tgccgacaat attcctgacc atatgatgta caaaggcatt cgctttgata tctaccacca
    46621 cataaggacc gtgacgcgtg acattaatat gcataacgtt gcgccacggg gtccgggact
    46681 gacactgcac cgcacggaac gaggtgaaat cattctcgcc cagcaagcat tgcgcagccc
    46741 gatgcatccg ttcagcgtcc agcggttcgt aaaaatgggt taccccttta ctcagtaccg
    46801 ccgggcgcag ccgatgattg tagatgatgt agcgataacg gcgagccgtg gcgctaaatc
    46861 gggcatgaaa atcatcaggt acagctttaa cccaacgcac ggcgatgtca ccaggtaaat
    46921 tcgcatttac gcccaacgtc cacgcagcgt ctttgcgctg cgcggtcgtt tcgaaatgca
    46981 ctacctgccc ggtgccgtgt acacctgcgt cagtacgccc ggcgcagaag acggtgatgg
    47041 gttcgttcgc cacctgggag agcgcctttt ccagcttctc ctgcacactg cgtacttcat
    47101 tctgccgttg ccagccgtaa tacttactgc cgtcgtactc aatgcccagc gcaattttat
    47161 aaactggcgg ttgttgctgg tcggacatta gtacagatac tcctgcacca gtttctcggc
    47221 gatttttact gccatcagcg cgccgccaaa gcgaacgtta tcggccaccg accagaactg
    47281 aacttgctcc ggcataccgt agtcattacg tacgcagcca acggaaagat gcggcgtacc
    47341 agaagcatcc cccacctgag tcgggaattc gttctcttca gagagcacaa tatcttcgcc
    47401 ctgagcaaac gcatcacgcg cttcttctgc tgccagcgga cgcagtgctt caaagttgac
    47461 catctgggca tgaccgtaga ataccggtgc ctggacgacg cttgccgaaa tcatcagccc
    47521 ttcgtcctgc aggattttgc gtacttcgtc aacgatacga cgttcttcac gcacgctacc
    47581 ttcgctatcc ggcagtaacg gcagcatgtt gaacgccagc tgacgcccga agaaatcttc
    47641 ttcatcaatc ggaatgccgt tgagcaattt cgcactctgc cccgctaacg catcgaccgc
    47701 ttttttgccc tgggcggagg ctgaaatcag gctggtaacg ctgatacgcg acaaaccgcc
    47761 ctgatcgatt aacggtttca gtgccgccag cagttggctg gtcagactgt ccggtacggc
    47821 gatgacattc cggttgcggt aatcggtcag tacaaacggg tttacttccg gcaccaccag
    47881 cggtacgtca ggttcgagag caaacaatcc gctgctatcg atcaccaggc aacctgagtt
    47941 ggtcgcttct tcaacccagg cagcggtagc ttctttgcct gcgacaaaaa acgccagctg
    48001 cgcctgcgtc cagtcgaatt cagcagcatc ctgcacggtg attgtcttac caccaaagcg
    48061 cagttgttcg cctgcgcttt cgttacgtgc cagtgcataa atttccccaa ccgggaactg
    48121 acgttcagcc agcgtttcaa gcagggcttc gcccacagcg ccagttgcgc ccaggacggc
    48181 aatgttccag ccttcagaca tggtggttta ctccagaaat agcaaagctc cctgccaata
    48241 ttacagcaga gagcatgaag aagagattaa cgtgccggat gatgaacggc gttaaaaccc
    48301 agtttacaca gcaatgatgc cgcgctggcg tcatcacaaa tcacatacag agatgaccat
    48361 tcacggcgct caagatagtt tttgcgcagt ttatcgaact cacccggtat cccggcgact
    48421 ttacgcagcg gtgcgtcatc gcggcgcaca tcatacacca aatgcaccag cctttttaga
    48481 gtcggctgat cgagcggacc atgcagcgta atgcgaccaa actctggcgc gggcagtaat
    48541 gtatccagcg caacgtgttg ttcatgccca atgaatttgc tataggcttc aaacacttgc
    48601 gtagtaccgc gtgctttacc ttccagggta tagcctgcaa tatgcggcgt gccgatatcc
    48661 acttttgtca gcaattccac attaagttcc ggctcgcctt cccagacatc cagcaccacg
    48721 cttaacttct ggccttcatt caggcaggtc agcagcgcgg tattatcgac gactgcgcca
    48781 cggcaggcgt taatcagaat cgctccgggc ttcaggctac ggatcagttt ttcatccgcc
    48841 agatgtcgcg ttttgtacgg cccgtcttta aagagtggcg tatggaaagt cagaatatcc
    48901 gcatgctgaa ctaattcatc cagcgagcgg aaatcaccct catctccacg gtcggcgcga
    48961 ggcggatcgc aaagtaaggt tttaatccct aacgcttcca gtcgtgcctg taaacggcga
    49021 ccaacgttac caacgcccac gatccccacg gtacgctcgt gcagtgaaaa tccatcgcgt
    49081 tcggcaagca tcagcaggga ggagaaaaca tattccacca ccgcaatcgc attacagcca
    49141 ggtgccgcgg aaaaaccaat tcccgcctgc tttaaccacg cttcatcgac atggtcggtc
    49201 cccgcggtgg cagtgccaac aaatttaatg ggttttcctg ccagcaaaga ttcattcact
    49261 ttcgtgaccg aacgcaccat cagcgcatcc gcgtctgcca gttgagccac ggggatggga
    49321 cgcccgggaa ccgcggtcac ctcacccaaa cggctaaata agtcgcgggc ataaggcata
    49381 ttttcatcaa caaggatttt cacgtttgtg ttacctgtat gagacgagag ttaaccggac
    49441 aagtgtgcca taatctcgcg gccaggcata cttgcgaaga tttcaggtat aaggatacgt
    49501 aatgatacaa cctatttccg gccctcctcc tgggcaacca ccaggtcagg gagataacct
    49561 gccgtctggc gcgggcaatc agcctttatc cagtcagcaa cgtacttcgc tggaaagctt
    49621 aatgacgaaa gtgacctcac tgacgcaaca gcaaagagca gaactgtggg cgggtatcag
    49681 gcacgatatt ggtctgtcgg gagattcacc gctgctttcg cgtcacttcc ctgccgctga
    49741 gcacaatctg gcgcaacgtc tgctggccgc gcaaaaaagc cattctgccc gccagctttt
    49801 agcgcaatta ggggagtatt tacgtctggg gaataatcgt caggcggtca cggattatat
    49861 ccgtcataac tttggtcaga cgccgctgaa tcagctctca ccggagcaat taaaaaccat
    49921 tctaaccctg ttgcaggaag ggaaaatggt tattccgcaa ccgcagcagc gcgaggcgac
    49981 cgaccgtcct ttattaccgg cggagcacaa tgcgcttaaa cagctggtga ccaaacttgc
    50041 ggcggcaacg ggggaaccca gcaagcagat ctggcaatcg atgctggaac tttccggggt
    50101 gaaagatggc gagttaattc cagcgaaact gtttaaccat ctggtgacct ggctacaggc
    50161 gcgtcagacg ctaagccagc aaaatacgcc gacactggaa tcactacaga tggcgctaaa
    50221 acaaccttta gatgccagtg aactggcggc gttatcggca tatatccagc aaaaatatgg
    50281 cctttctgcg caatcatcgc tttcttcttc ccaggccgag gatattctta accagcttta
    50341 tcaacggcgg gttaaaggga ttgatccgcg tgatatgcaa ccgctgctta atccttttcc
    50401 accgatgatg gacacgttgc aaaatatggc aacgcgtccc gcgctgtgga tactgttagt
    50461 cgcgattatc ctgatgctgg tctggctggt tcgttaaccg cgacgaaacg acagtatcgt
    50521 gacaataatt cccagcaccg cagagatcgc cccggcaaga aataccgatg agtaaccaaa
    50581 cgtggtcgcc agcattcccg ccagcggccc ggagacgccg agggcgatat cctgaaacgc
    50641 ggcgtaaccg cccagtgcgg tgccgcgaac ttgtgagggg acacgtttaa ccacctccac
    50701 gcccagcgca ggaaagataa gcgaacatcc ggctccggtt aacgccgcgc ccgctaatgc
    50761 gacccacgca cccggggctt gccagagcag caacaagccc accgtttcta caagcagaga
    50821 gacgatcgcc actttcacgc cgccaaaacg gtccggcatc cagccaaaca tgacgcgcat
    50881 cacgacaaat gcgccgccaa acgcggtaag agtaaagccc gccatcgccc atcctttgct
    50941 ggcaaagtag agcgaaacga aagtcccgat aaccgcaaaa ccaacgcctt gtagtgccag
    51001 acctaaccct ggtttccaga taagcccgac aacgctccat agcgatggac gttctcccgc
    51061 cagggccggt actttgcgca ctgtgccgtt acaggcccac gccagtaagg gtaatgccat
    51121 tgtggtgagc gccagtgcgg caaaaccgta atggctatga atcaacaggc caagcggcgc
    51181 accaacagcg agggcaccgt aaatagccat tccgttccat gacatcactt tgccggaatg
    51241 ttttggccca acgatgccta atccccaggt cagagcgccc gtcagtaact ggctttcacc
    51301 aaagccaaga atcaaacgcc cgacgaccaa cagagcaaat ttgaacggtg cggggacggg
    51361 caaaatcgcc gccaacagca gtgcgccccc cgccagacca caagctaaca tcccctgaag
    51421 cgccgaacgt tttgcgccat attgatcggc cagtcgcccg gcgtaaccac gcgtcagcac
    51481 cgtagccaga aactgaatcc cgacggcaat gccgaccata gtgttgccat agcccagttc
    51541 atgatgaaca aacagcggga taaccggcaa cggtaaacct acggtcatgt aggtgagaaa
    51601 aaccgcaaaa gcgatgcgga agagcgaaaa attggcagaa gatcgtgttt cggtttggct
    51661 tacagcagtc atgcattact ccagaatgca gcgcaaggcg aggagtatcc ccgtctcatc
    51721 tctctggttt cagggttacg gtgcgttggc aggatttaac gcgtacgtct ttttagcagg
    51781 atatcgacaa agcgggaagt ttgcctggaa ctggcggcga ttgtcaatga tgtgaaaaag
    51841 ggaaccatcg ggttcccttt tgcgttagtg ccggaggccg cattggtgcg taaccactcc
    51901 gaattaatct ttcagcttgc gcattaccag cgtggcgtta gtgccgccga agccgaagct
    51961 gttagacata acggtggtca gttcgcgatc ggtcgtttcg gtcacgatgt tcagacccgc
    52021 agcctgctcg tccagctctt caatgttgat gctcggggcg ataaaaccgt gttccagcat
    52081 cagcagagag tagatagctt cctgtacgcc agcagcgccc agtgagtgac cggtcattgc
    52141 tttggttgca gaaatcgccg ggctcttatc gccgaacact tcacggatag ctgccagttc
    52201 tttcacgtcg ccaaccggag tcgaagtacc atgagagttc aggtagtcga ttggggtatc
    52261 aacaccgtgc atcgccatct tcatgcagcg cactgcacct tcgccagacg gagcaaccat
    52321 gtctgcgcca tcagaggttg cgccgtagcc aacgatttca gcatagatgt gagcaccacg
    52381 cgccagcgcg tgttccagct cttcaaccac taccataccg ccaccgccag cgataacgaa
    52441 accgtcacgg tgagcgtcgt aagtacggga ggctttttcc ggggtgtcgt tgtatttagt
    52501 agacagcgca cccatcgcgt cgaattcgca agccatttcc cagcacagct cttcgccgcc
    52561 gccagcaaac acgatgtcct gtttgcccag ttggatctgc tctactgcgt taccgataca
    52621 gtgtgcggaa gtcgcacacg cggagctgat ggagtagtta acgccgtgaa ttttaaacgg
    52681 cgtggcgagg caggcagaaa cgccggatgc catcgctttg gtgaccacat acgggccaac
    52741 cgctttcagg ccgcgcgggc cgcgcattgc gtcagcgccg aaaacctgga aacgcgggga
    52801 gccgccgccg gaacctgcaa tcaggccaac gcgcgggtta ttctggtaag cttccgggga
    52861 gaggccagca tctgcaattg cctgctccat agaaaggaat gcataaatgg atgcgtcgct
    52921 cataaagcgc acaactttgc ggtcaatgag gccagtggta tccagtttta cgttgcccca
    52981 gacgtggcta cgcatgccgg aatccttcag ctcctgagag aaagtgatcc ctgaacgtcc
    53041 ttcacgcaga gatgccagga cttcctgctg gttattaccg atgctggaaa caatgcccag
    53101 gccagtaatc actgcacgtt tcattcaata cctctgtaag tcgcacatag agtaagtttc
    53161 gcatgcacaa tagcgtacac ttgtacgccg aacaagtccg atcagccaat taatagagaa
    53221 atttgcgcag cctggcacac atcgctaaga tcgagccacc gcctgtaaga cgagtaactt
    53281 acgtgaaaca ctacgccata caacctgcca accttgaatt taatgctgag ggtacacctg
    53341 tttcccgaga ttttgacgat gtctattttt ccaacgataa cggactggaa gagacgcgtt
    53401 atgtttttct tgggggtaac caattagagg cacgttttcc tgagcatcca catcctctgt
    53461 ttgtggtagc agagagcggc ttcggcaccg gattaaactt cctgacgcta tggcaggcat
    53521 ttgatcagtt tcgcgaagcg catccacagg cgcaattaca acgcttacat ttcattagtt
    53581 ttgaaaaatt tcccctcgcc cgtactgatt tagccttagc gcatcaacac tggccggaac
    53641 tggctccgtg ggcggaacaa cttcaggcgc aatggccttt gcccttgccc ggttgccatc
    53701 gtttattgct cgatgaaggc cacgtgacgc tggatttatg gtttggcgat ataaacgaac
    53761 tgaccagcca actggacgat tcgctgaatc aaaaagtaga tgcctggttt ctggacggct
    53821 ttgcgccagc gaaaaacccg gatatgtgga cacaaaatct gtttaacgcc atggcgcgac
    53881 tggcgcgtcc tggcggtacg ctggcgacct ttacgtctgc cggttttgtc cgccgcggtt
    53941 tgcaggaagc cggattcacc atgcaaaaac gtaagggctt tgggcgcaaa cgggaaatgc
    54001 tttgcggggt gatggaacag acattacccc tcccctgctc cacgccgtgg tttaaccgta
    54061 cgggcagcaa caaacaggaa gcggcaatta ttggaggcgg tattgccagc gcgttgttgt
    54121 cactggcgct attgcgtcgc ggctggcaag taacgcttta ttgcgcggat gaggctcccg
    54181 cactgggtgc ttccggcaat cgccaggggg cgctgtatcc gcttttaagt aaacacgatg
    54241 aagcgctaaa ccgttttttc tctaatgcgt ttacttttgc tcgtcggttt tacgaccaat
    54301 tacccgttaa atttgatcat gactggtgcg gcgtcacgca gttaggctgg gatgagaaaa
    54361 gccagcataa aatcgcacag atgttgtcga tggatttacc cgcagaactg gctgtagccg
    54421 ttgaggcaaa tgcggttgaa caaattacgg gcgttgcgac aaattgcagc ggtattactt
    54481 atccgcaagg tggctggctg tgtccggcag aactaacccg taatgtgctg gaactggcac
    54541 aacagcaagg tttgcaaatt cgttatcaac atcagttaca ggatttatcc cgtaaggatg
    54601 acggttggtt gttgaatttt gcaggtgatc agcaagcaac acacagtgta gtggtactgg
    54661 cgaacgggca tcaaatcagc cgtttcagcc aaacatcgtc tctgccagtg tattcggttg
    54721 ccggtcaggt cagccatatt ccgacaacgc cggaactggc aaaactgaaa caggtgctgt
    54781 gctatgacgg ttatctcacg ccacaaaatc cggcgaatca acatcattgt attggtgcca
    54841 gttatcatcg cggcagcgaa gatacggcgt acagtgagga cgatcagcag cagaatcgcc
    54901 agcggttgat tgattgtttc ccgcaggcac aatgggcgaa agcggttgat gtcagtgata
    54961 aagaggcgcg ttgcggtgta cgttgtgcca cccgcgatca tctgccaatg gtaggcaacg
    55021 tgcctgatta tgacgctaca ctcgtggaat atgcgtcgct ggcggagaag aaagatgaag
    55081 cggtaagcgc gccggtttat gacgatctct ttatgtttgc tgctttaggt tcgcgcggtt
    55141 tgtgttctgc tccgctgtgt gccgagattc tggcggcaca gatgagtgaa gaaccgattc
    55201 cgatggatgc cagtacgctg gcggcgttaa acccgaatcg gttatgggtg cggaagttgt
    55261 tgaagggtaa agcggttaag gcggggtaat ctgctctggc attgcttgcc ggatatggcg
    55321 tgaacgccgc atccggcaca ttacttactg ctgtgaggcc tgctgaaaca ggtgttccca
    55381 catatcggtt accagcgcct ggtcacgcgg tgacaattca cccgcgccaa tggctttttc
    55441 cagactctgg ctaacggtcg tatgtaccgc ctgggcggag tggtcctcac cactttccag
    55501 ttctgcgatg gctaatgtca ggtggccacg caaataccca ctggcaaaca actcatcatc
    55561 actggcatgg tcaaccatac cgtcgattaa tgccagaatg cgtgattcaa actccgcgat
    55621 catcttcttt cctcattgta aaacgtggcg ctggctttag ttgagcgctt ccggccacgg
    55681 gaactgttcc gccgtaagtt ccggcgtgtg ataataattt tgtaatgctt taatgaagcg
    55741 tgccggacgt tcgggaatgc cgtttgccag ataatccatc acctgcgcat gtacccgccg
    55801 ttgaaacacc acacgatccg gttcgaaatc cccttccaga ttgtcgcagc taacattaaa
    55861 cggatatccc gccgccacgc agaacaacca gtccagcgcc tgcggcttca cttcaacatc
    55921 ttcaaactga ctttgcgtct gggcatcgcg tccgtccggg caataccagt aaccgaaatc
    55981 aaccagctca cggcgcgctt tcccggcaat acaccagtgc gaaatctcgt ggatggcgct
    56041 ggcataaaag ccatgagcaa agacgattcg gttatacggt acttccgcat cagcaggaag
    56101 atagatcggt tcgtcgtcgc ctttaatcag acgggtatta aaatcatcgg caaagcagct
    56161 attaaaaatt tcaatcaact gctcatagtg gtgtgtactg ttcattagtt catccccaac
    56221 cagtggagga tctcctgtcc atggctatcg taaagtaatt tggcactcat caccgccgag
    56281 acgataacga tcatcgggcg gatcagcttt tgtcctttgc tcaacaccag tcttgacccc
    56341 atgcgcgcgc cgaggaactg tcctaccaac atcacaaatc ctgtcgccca aatcactttg
    56401 ccgccgagaa taaacagcag caaaccaccg atgtttgacg ttgcgttgag taatttggcg
    56461 tgggccgtgg ctttggcgag gttgaatccg cacagcgtaa caaaggccag cgcgtaaaac
    56521 gacccagcag ccgggccaaa gaatccatcg taaaaaccga cgcagccccc cgccaccagc
    56581 gcaaatggca gtccatacat ccggcgctgg cgatcttctt ctcccagttt tggcatcagc
    56641 aaaaaataga ggccgataca aatcaccagg atcggtaaaa tctgccgtaa gacatcggcc
    56701 tgaacatact gcaccaacag cgcgccgctc attgagccga caaaggtcat ggcgatattg
    56761 agtttctgat cgcttaagct aaccactttg cgccgaataa agtagatagt ggcggaaata
    56821 gagccgccgc aggcttgcag tttattagtt gccagcgcgt tagccggaga catccccgcc
    56881 gccatcaatg ccggaatggt gagtaaccca ccgccaccgg caatcgagtc gataaatccc
    56941 gccagcatgg cgacaaaaaa gagaactccc agcaacagcg gggaaaccat aaacaggcta
    57001 ttaaacgttt ccattagatc acgtgctcat ccagtagcgc ctggcaggaa ggcggcaacg
    57061 gaggcggtgt cttcttctca ggctttgttg ttcccggttt tggtggttca aaccagcttt
    57121 gcagttctgc cccgcaacca tcgcctggtg gcggtaaagg ttgatcttca cactccagac
    57181 tatcggcagg acaacgtaat cgtacatgca tatgcgcgcg atgctggaac cagggtcgca
    57241 ctttacgtaa ccagtcgcga tcggtgcccg catcaaggca aagttgttgt ttaatcgccg
    57301 gattaacaaa aatgcgcgtg acgtctttgt cctgggcggc gagtttgatc aagctgaaaa
    57361 tttctggctt ccacagcgcg gggacaacgt gtttaccgtc gcgggatact aagtccagtg
    57421 cttgcgggcg caagagctgc gcggaggtcc agcgtgtttt tggcagttgc aggaagatat
    57481 cgacatccag tccggtctgg tggctggcgt gaccgccgtt gaaacgacca ccagcaggca
    57541 tccccatatc gccaatcagc accgtaccca tgcccagatt gctcacctgg cgactcagac
    57601 gctggataaa catcaccaga tccggatgtc cgaaatagcg acgctgatcg gtacgcatga
    57661 cctgataatg ttcggactgt atcggcaacg tgtcagcacc gacgatacag ccattagaaa
    57721 aactgcctat cgattgtgcg ctacccggca caggttgggt tattttttgc cacggcgtcg
    57781 ctgccaggct ggcgctactg gcaagcagag ccagcagcgc aatcgcggtt ttgttcattt
    57841 tttaccagcg tggaatatca gtcttcacat cggcattttg cgcccgttgc cgtaacaggt
    57901 gatccattaa aacgatcgcc agcatcgctt ccgcgatcgg caccgcgcgg atcccaacac
    57961 aaggatcgtg acggcctttg gtgatcatct caacttcttc gccaaagcgg ttaatggtgc
    58021 gccccggcac ggtaatactg gaggttggct tcagcgccat atgggcaatg atttgctgcc
    58081 cgctgctgat accgccaaga atgccgcccg catggttgct ctggaaaccg tctttggtga
    58141 tttcgtcgcg gttctggctg ccacgcagcg ctaccacgtc aaaaccatca ccaatttcta
    58201 cgcctttcac cgcgttgatg ctcatcagcg catgggcgat gtcggcatcc aggcggtcaa
    58261 agaccggctc gccaagtccg gcggggacgc cactggcaac aacggtgact ttcgcgccga
    58321 tggagtcgcc ctcttttttc agcgcgcgca tcagttcatc taacgcgtcg attttgtccg
    58381 ggtccgggca gaaaaacgga ttttgctcga cctgcgacca gtctttgatt tccagcggaa
    58441 tgtcacccat ctgggtcagg cagccgcgaa tctcaatgcc aaatttctcg gcgagatatt
    58501 ttttggcaat cgcccctgcc gccacgcgca tggcggtttc gcgggcggaa gagcgcccgc
    58561 cgccgcgata atcacgcagg ccgtattttt gttcataggt gtaatcggca tgacctggac
    58621 ggaaaacgtc cttaatcgca ctataatcct gagaacgctg gtcggtattt tcgatcaaca
    58681 aaccgatgct ggtgccggta gtaacacctt caaaaacacc ggagagaatt ttgacctgat
    58741 ccggctcgcg gcgctgggtg gtatagcgcg atgtcccagg gcgacgacgg tcgaggtcat
    58801 gttgcaggtc cgcttccgtc agcggaatgc ctggcggaac accatcgacg atgcagccga
    58861 gcgccagccc gtgcgattcg ccgaaggtgg ttacgcgaaa gagttgtcca attgtgtttc
    58921 cagccatcac ggctccgtta ttgttgtgtt tgcgtgttta cttaatcttt ataaatcgcg
    58981 aaatgttcac gggccgccag cagctgctct ttggtgagca taaacacacc atcgccgccg
    59041 ttatcaaact ccagccaggt gaacggaaca tcgggatatt gttccataag atgtaccatg
    59101 ctgttgccga cttcacaaat cagcacacca tcatcagcga ggtaatctgc cgcgttaccg
    59161 agaatgcgac gcgtcagttt cagaccgtcg gtgccagatg ccaggcccag ttccggctcg
    59221 tggcggtatt cgtttggcag gtcggacata tcttccgcat cgacatacgg cgggttggtg
    59281 acgatcaggt cgtactgcac tttcggcaag tcgcggaaca gatcggaccg aataggaatg
    59341 acgttgtgga tcagaccgtg ttcttcgata ttctgttcgg caaccgccag cgcgtcggga
    59401 gagatatcta ccgcgtcgac ttccgcttcc gggaaggcat aagcacaggc aatcgcaatg
    59461 cagccgcttc ctgtgcacat atctaaaata tgctgcggtt gcttgctgat aagtccggca
    59521 aatttattgt tgatcagttc accaatcggc gagcgcggca ccagcacacg ttcatcgacg
    59581 taaaattcat gaccgcagaa ccaggctttg ttggtcaggt aagccaccgg aatgcgttcg
    59641 ttgacgcggc ggatcacgcg ctcaacaata cggtgttttt cgctggaggt cagacgcgcg
    59701 gtgcgcatat cttctgggat atccagcggc aggtagagcg atggcagcac cagctgtacg
    59761 gcctcatccc acgggttatc ggtgccgtgg ccgtaccaga tattcgccgc gctgaagcgg
    59821 ctcaccgacc agcgcaacat gtcctgaatg gtttgcagct catttactgc ttcatcaacg
    59881 aaaattttat ccacgtattc ctccagggca tgatcgcaat aatttcggcg gctagtttgc
    59941 catgaagatg acgataaatc agcattcaca cgcggtgagt gaggaaaaat acgttttaag
    60001 cgatcgattg tacggtgagt cgggtaaact gtaggaaaat taaaaataga gacagataaa
    60061 tgaaaaagaa aacaacactt agcgaggagg accaggcgct gtttcgccag ttgatggccg
    60121 gtactcgcca acttaagcag gacaccattg tccatcgacc acaacgcaag aaaatcagcg
    60181 aagtgccggt caagcggttg attcaggagc aggccgatgc cagccattat ttctctgacg
    60241 agtttcaacc attattaaat accgaaggtc cggtgaaata tgttcgcccg gatgtcagcc
    60301 attttgaagc gaagaaactg cggcgcggtg attattcacc ggagctgttt ttggatttgc
    60361 acggtttgac gcagctgcaa gccaagcagg agttaggcgc attgattgcc gcctgccgcc
    60421 gcgaacatgt gttttgcgcc tgtgtgatgc atggtcatgg taagcatatt ttgaagcagc
    60481 aaacgccgct gtggctggcg caacatccgc atgtgatggc atttcatcag gcaccgaaag
    60541 agtacggtgg tgatgcggca ttgctggtgt tgatagaagt ggatgagtgg ctgccgccgg
    60601 aattgccctg acatcatgac gggcatacgc tttcactgac agacgccgac ggttaagtgt
    60661 aagattatcc aaacagaact caacgcaggg cactcaatga tgaatatccg cacgcttaag
    60721 ctcactaatc tggggcggtt tgaagaactt gacgttcatc tggctccagt ggaggagttc
    60781 aagagcaatg tgaccgtttt tattggtaat aatggtgcag gtaaaacatc aatattaaaa
    60841 tcgttggcaa ccagcctgag ttggttcgtt gcccgagttc gtactgaaaa gggtaacggt
    60901 agccctattc ctgaagacgc tattctgaac ggtaggagtt cggcgacaat tgaacttcag
    60961 gtactgaata cgcatccagc gacggaggcc gctacgccct accgttggtt gcttgccaga
    61021 acggccagtg ggaaaaaatc gaccaccgcc tccagcctgc aagaggccag ccaattggct
    61081 gcgttttatc gagatcaata cacccagaat agcggggcat ccttcccgct tatcgccttc
    61141 tatcccgtag aacgtgtcgt gctggatgtg ccgttgaaaa taaaagaacg tcataatttt
    61201 ttgcaactgg atggctacga taacgccctg aatcagggta ttgatttccg ccgtttcttt
    61261 gagtggtttc gcaatcgcga agatgcagaa aatgaatcgg gcttacccca agacgttctg
    61321 gataagctca gtaccaggat agatctcgat aacgccgtct taaatgcatt aacggcaatc
    61381 atggcctcgt cccgggatcg ccagttgacc gccgtcagaa cggccattag tcgctttatg
    61441 ccagggttca gcaacttacg cgtcaggcgt aaacctcgcc tgcatatgtc gatagataaa
    61501 aatggccaga cactgaatgt gctgcaatta tcgcagggtg aaaaatcact gatggcgtta
    61561 gtcggcgata ttgctcgccg cctggcaatg atgaacccga tgttagaaaa cccgctaaac
    61621 ggcgagggaa ttgtattaat tgatgaagtg gacatgcacc tgcatccaac atggcagcgt
    61681 acaatcatcc agcgtctgac gacaacattc ccacattgcc agtttgtctt aacaacccac
    61741 tctcctttag tgatcagtga ttgcaaagat gtgctggttt attctctgga tgatggcgaa
    61801 ttaacgcagc tcccgtctct gtatgggcaa gatgcgaata ctgtgctttt gaatgtgatg
    61861 gatacggata ttcgcaatgc gacagtggca gaaaaactta acgatcttct ggatctgatt
    61921 cagaaaaacg actttatcaa cgctaacgct cttctgaata cgctaagcct ggaacttcct
    61981 gaaaaccatc ttgaactggt gaaagccaga atgcttctgc gcaaacagga aattaaacat
    62041 gcgcgaaata actaaagggc aaccgccggc cagtttgcaa cagtgggtga gagcaaaacc
    62101 acgggataaa aatgccaatc agtggtttca ggaactttat gcgcaaaaaa aatgggatat
    62161 cgttggcgat ctcagccagc agtgcgctca ggagcaattt tatctctgtg cttattgctg
    62221 cgatcgcgtg acaggtacaa accgcgatac cgttaatgaa catgtcgaag ccagggattt
    62281 agctcctgct cgcagtctgg aattcacgaa tatcgttgca agctgcaaaa caaaaggcca
    62341 gtgtgacgac tcgcataaga accagccatt gctgttaacg ccgcttatgc cggaatgtga
    62401 aaccgagttt atcttcaaga tcagtggtcg aattgaaggg acgacgccga gagctatcga
    62461 tgcaattaag gtactcaacc ttggcgatag tgaacgtaat aatcgggcat tgattgaaaa
    62521 acgtaagcag ctttccgaca gccttctgtg ggctaatggc attgcccctt cagaggggct
    62581 tgaggatgac gacctgctgc aagcggttat cgacgaatta ctcacccccg tcgacggtta
    62641 tctggcacct ttcgctcccg tggtggcgaa tattctaaaa aactggatga ccgcatgaca
    62701 taacggatgg ccgatacccg accatccgta ccagagtcac tacaattcat tcaatacata
    62761 ctgaaaacga cacgtagaat caatcggttg tcggctactg gtattcacct tcaccacaat
    62821 atcgtgcagt tgtttatccg ttactggatg acgtgtaggg gaaaccgtta ctgtcgattt
    62881 atcgcaaccg taagaggtaa aggttaacag ttccgagacc acgcggcagt atgctcctct
    62941 gttatcaaaa acgctgccat cacagagttt gccgtcttgc atcaggtagg tcgaaagcgt
    63001 ggtggtgatg gtcgagccat tggactgtaa ctgcaacgct ttactatggc tgacataatt
    63061 ctcattccac gaaatatcaa atgaagtcac cggaatcgtt gggcatgccg tagcatgatc
    63121 cgttgggcca gtatatattc catatgcatg ttgatctgat acctcataaa aagaggcgat
    63181 ccacggacag ccataattgt cagattgaac ggtaacttta aatgtctcat atgcgcatcg
    63241 aaacagcgtc gtatttatcc cagggcaaaa cgagttatca gtgctactat agtcaacaag
    63301 agtcaacgtt ggcgcagggc cagaccccgt ccatgaaacg accctcgcgt cagtgcctat
    63361 atacccggta gtattgtata ccccataggc aacctcgcct ggggttaaca cagtgacatg
    63421 taaggctcct gtggtgaaac ctgctctccc catcccatag taaattttca cactatcaaa
    63481 agttgcgctg gtgagtttat ccctggcata actctttggc gtacctacac tcattacgag
    63541 caatatcagg ctcgcgaaaa acatcatcca ttttttcatc ttaaaaatac tcaaaggttg
    63601 ccgtcgccgt ggcgctgaaa tcaccgggcg tcacatcccg cccacttttt gtctgtaacc
    63661 aggcattgaa gttgagagtg ttactgccct gattcagcgg gaacgtcacg cccgtcgtgt
    63721 cgttgatagg caccgctgcg cccgccgccg tttcaatacc aatcccgacc ccggacgctg
    63781 acgatgaggc gtcgatagcc agcaatccgg gcagttcgct gtcttccgtt cccgccagcg
    63841 tcactctgac gctaaacagc gtagagcttt tgcaatcctt caactgaaag accagcggca
    63901 ctcgatctga ctgcccaaga tgcattaaat cgctggcggc aatggtagga aattgcacct
    63961 ccgccagcag actaccgttg atcaccggtg tacaggattt accgagcaga ttgccggtga
    64021 agtgcaggtt gtcgaccgcc ggagcagtac tgctgcacag taacagcaga ctgctgataa
    64081 aaaccaacgc atgttttttc gtcattggta atccacctgt aacgtagccc aggcttcaaa
    64141 gttggcctca ggcaaatcga cgccgctctt tttgaccggt accgccgtta acgccggcaa
    64201 agccgtttca tccaccacca gtggcgtatt cagcttaaag ctctgccctg cctgtttaag
    64261 ccgaatcccc aggcctgcga tgtccgtgct taccgccgca tcgtcaaagt cgctctgcgt
    64321 gccgctccag ctcaaggtca tttccagtaa agggtcacga accggtgtat cgcaagtaat
    64381 gcgatacggc acgatttgct cataattact gccgttaatg tcgtcgatat tcacgtcctg
    64441 aaaggttaat tcaatggttt caccgtcgct aatggtgcag ttaggcggct gcactaaata
    64501 accgtgaaaa gtgacatttg agagcgccat ggagcaaaag ccccacagca taagaagtga
    64561 gatccgtttc attggtaatc caccacaatg gtggcgctgg cgctaaattc cgccgccgtt
    64621 aacgacgtgc cgctctgttt caccggaacc gcttccagcg ctggtgcgcc cgaggagaaa
    64681 ttaaacggca gccatgcgcc agacgttaag tcgagtatcg aactatcgct ggccttctga
    64741 atccgaatac caaacccagg aatccccgtg ctgatcaccg tttcaccgtt aatcacgacc
    64801 gttgccgcct gcatctgtag acgcaggtca tccatggcca ggttgttaca gacaagcttg
    64861 taatcaatgg ggcgcttata attcacgcca ccaattctgg taatgacaac attaccgaac
    64921 tccacctccg cgcccgttac cgtacaagga ggcggagcat caacaagcac ccgtaaaatc
    64981 atatccaccg atttgctccc tgccgtcacg gagcaactac cgatgcagcc caccagcaac
    65041 cacgcccacg atcctttcat cctggctctc ccgttatcag cctttgctgc tttgatcttc
    65101 atccaccttg caggtgtccc cttcacagcg gaagatcagc ggcaggcgcg cgccgtagtc
    65161 gttgatgtag gtcagcaccg gggcgctgtc catttttgcc tttaacggct gtgacgtttt
    65221 cggcgacatc accagcggtt taaacccggc agcggtcggc cctttcttct gtgtgctggc
    65281 atcgctgatg atgacgtggt atggcgtcgg gttattgacg gtatagtcct ggccgctgcg
    65341 cgtgagcgtc accttaaact gccacggttt tctcatgtcg atcttctcca gcgcctttgg
    65401 tcgccagaac agcttgatgc gcgtttgcag ggcaatttgc agagtgttgg ctttcccggt
    65461 ctttggcggg atctcacgca cgttgtaata gaacaggctt tcgcgatcgg acggcagcgt
    65521 gtgaatgtcc ggcagcgcct gaatcttcac ctggccgttc atcatagcgt caatacgctg
    65581 caccggcggc agtaccgcca gcggcgaggt gattttgttg cccttctcgt cttccagcca
    65641 gctttgcgcc aggtaaggca gcttttcgtt gttgttacgc aacgtcacgc tgatcgattt
    65701 atcgctttcg ttaaacacca gacgggtgcg gtccggggtg accgaggcgt gcgccgccag
    65761 gctgacggtg gaaagcagtg ccgccagcgc cgtgctgacg accattgaac tggataattt
    65821 ataagacatt gatcgttcct taatcagatt attgagtagc tgaaattgac gtcggcgctt
    65881 ccgttggtgt gacttgccgc gtctggtcct gaataacagg cttaatgtct ggcgctgaag
    65941 aatcaggggc tgccgttccc ttttgttcac acggcaacaa caggccgctg aacagatcgg
    66001 caggtagcgg cttcggcaat acgatctcgc attgtgcgct gccttcccag aacaccgtca
    66061 tatgctcacc cgcattgact cccgccagat agacattgcc ttcatcatcc acaatgccaa
    66121 cctgctgctg ctcgtcgttt ttcacttccg cgccaaacgg cgggtagctg ccgtcacgca
    66181 accgcagtac cgccatcgct ttttgcccgc tgatcacttt gaatttgcga tagccaattg
    66241 caccttccgt cagggttgcc tgtaccaccg actgggtggc ttccgcatct tctggcaggt
    66301 tgtttaaatc gatatacgcc tgattgcgat agtagttgtt aatatcggcg accaccgcct
    66361 tgccaaacat attggtgtac accggcgcgc cgttgctttc gaccggcaca ttggcaatcc
    66421 cgtcggcgtc aatcagcaag cgcgtaccgc ccatgctttg agtgcgatgc agcgccccac
    66481 catgcgcggt cagcgttgcc ccgccctgta aggcgatccc cgccgagcgg tattccccct
    66541 catggtagtt ggcgctgaga tcaaccttcg ccagcgagcc gtcgtgactc agataaccat
    66601 ccacgctgcc gtgctgttcg ctggtaccga cgttaacctg gtagtgcgtt gcgtcatcaa
    66661 cgcgcttaaa gtaaccgacc tggctgctgt ccgacccact gccgtaggag ccgttgtagg
    66721 tcacggtgct gctgtcgctc cacggaatgc tcatgctgag gtacatcccc ttatccgcgt
    66781 tatcgtcata ttcgtagcga tagccggtca ccgagatgct catgttgcga atactcccca
    66841 tattaaaata gtgggaaaac atcaggttat agtttgtctg ttccgggcga ttccagtaag
    66901 tacgatggga gtagttgaga tagatcgaga cacccgcagc ggcaaagttc tggttatagg
    66961 tgatcgtata catctctttg tcgttaccgg tccgcgccat gtccgactgg ttcgcgtcca
    67021 gatactcgct catggtcatg aagttctttt cagaaaaacg gtagcctgca aaggtgacgc
    67081 ggctgttgag ttcgtcaaag tctttggcat agctcacgcg aaaggagttg ccgtccagtt
    67141 ttcctttgcc gtatgcgctg tcatgatcca ggttgacgtg cgagtgagtc acatcgaacg
    67201 ccagcgcgcc aaactgtgcg aggtcgcgcc ccacccccat cgccgccgac tggtagtgtt
    67261 catctgccag cgcgccaccg tagagcgacc agccatctgc caccccccat gacgcttctc
    67321 cgccggagaa aaagccgcct tcggtcttgt ggttccagtc ttccggacgc cccatcatca
    67381 ctttgtaacg cacctgcccc tggcgcgtga ggaatggcat agatgcggtg gtaacgtcat
    67441 attcctgcac ctgaccattc tgttcttcaa cgcggacgtg cagtgtgccg gagacggagt
    67501 cgccgatatc ctgaatgcgg aatggcccgg cgggaacctg ggtttcgtaa agtacccggc
    67561 ccatctggct aatggtgact tttgcactgc tgtgcgccac gccggagaca tccggcgcat
    67621 agccgcgcag gttgggcggc agcatctggt catcggtgct gacgctgctg ccaatatagt
    67681 taaagccgtc gaaaatatcg gagttgagat aatcttcacc cagcgacagc ttggctttta
    67741 aagagggtaa ggcccgccag gcgtaataac ggctccagtc ccagtttttg ctcgttgtgc
    67801 tgttactgct gtcatcgtct tcgtcgtcgt tgctgcgggt gtgctgataa tcactttgcc
    67861 agtcagcgcg gaaacgccat gcccccaggt tcgccccaac ggtaccgttg ccgctgatat
    67921 catgtgagtc ctcgcccccc tgctcctgat gacgggtttg cgcattgagg ctgtagtcgg
    67981 caatcaggcc aggaataccg tcgtcccagc gtgagggtgg gtcccagtcg ctgctggtat
    68041 attcgagata agcctgtggc actgtcagca gcaacgccga ctggcttaaa tcattctcga
    68101 cttccatccc atctaattgc cccggtttaa ggcattcatc gttgtgcgtc cactgcaggc
    68161 tttttgctat cccttctttc agccccagcg ccgccactaa ctcaggtgtc aggcaggcat
    68221 acgtttttgt tggatcgttt tcagaaacat accagttaat gtcgtattca tcagaaaggg
    68281 gttgtttatt tataaataca cgtaaattat attttcccgc gtcgacatac cctttttttg
    68341 aaaacttacc gagatcaatt ttcgtgtcgc cctttaactc aaggaaacgg gggtcaaatt
    68401 gaatggaatc atcagcccat gcattgactg atccacctga gattgccagc gcaatatagc
    68461 aggcgattcc ccgcagccga aaatttgagt gattaggcat acacatatcc gtttgtgaaa
    68521 cagtcgtaaa tctgttgcgt gttgaaaaac cccacagcag aacgctgtgg ggttgtcaca
    68581 tcagagatag gtaatctgga atgtggtcag ggtttcgaac tggccgagat ccggcgcttc
    68641 ggtttcaccc accagccagg ctttaaagtt cagcgtttgc ttgtctttac ctttgctggt
    68701 tgaagcatcc atcacgattg gctgaacaat cttttcgccc actttataac ctttgccatg
    68761 ggtatcgccg atcaccaggc tcacattctt catggcaaca ccgctgtcaa cgttgaataa
    68821 cgcatagtta tctgtgttgg ctggccccgc gtagttagta ccggtgaacg tggtctccat
    68881 gtttgtttca gtggaaaaca cgcagtcctg taaacggatc tggaaatctt tcggtgtggt
    68941 ggtgccaccg ccggtcagtt tagccgcacc gatgtcaccc atatcgactt ccagtttgtg
    69001 atcgtctgga acgatagagc acggggagtc ttcaatggtg ccgtagaagc gcgcggtacc
    69061 gttgttgcct gctgcaaatg cagaactgga aacaactgcg cccatgacca tcgccgcagc
    69121 aatggctgtt ttggcaaact tactcattat ttgtccttaa atcattaaga gttataatat
    69181 aaacacctga cataaaatta atatatatta tgcccgatat ttatagttag ccattgaaca
    69241 tatacactcc aatataatca tagaatgtaa acaagtattc tctggtgtgt ctgtatgttg
    69301 gtcttatcta taaaaaaact caatttagta atacttaaac actttatgta gattttatta
    69361 attaatacat ctacaaaata ctttcaccac ttcccaacaa aaaaacatgc gaattatcaa
    69421 caaaaaaaca aactattata atcaacaaaa atgaattgct tataaagcac actaaaaaaa
    69481 ttataatgac cttaccatca tttattgcta aaatttaata ttaatta
//
LOCUS       DADXDL010000012        68356 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.012, whole genome shotgun sequence.
ACCESSION   DADXDL010000012 DADXDL010000000
VERSION     DADXDL010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 68356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 68356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..68356
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.012"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            24..818
                     /locus_tag="IRB70_001048"
     CDS             24..818
                     /locus_tag="IRB70_001048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
                     /protein_id="HBC0630995.1"
                     /translation="MTLPTTIYSFPAYSPRFSSTDKPVKLKFHQYARATLLSNRGRDH
                     NCDGRHTVEIHKLDLSDWQAFNKLATRCNAYDGITMNGDNSFGWSHEATLDNIHAQKY
                     NKAYAGARLTAELKYLLQDVESFKPNSKYTIHEVVLGPGYGTPDYTGQTIGYVVTLPA
                     QMPNCWSSELPTIDLYIDQLRTVTGVSNALGFIIAALLNAYSDLPHDLKIGLRSLSSS
                     AAIYSGLGFERVPQDRDISCARMHLTPANHPELWTQENGEWIYLRN"
     gene            complement(889..1338)
                     /gene="rplI"
                     /locus_tag="IRB70_001049"
     CDS             complement(889..1338)
                     /gene="rplI"
                     /locus_tag="IRB70_001049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBC0630996.1"
                     /translation="MQVILLDKVANLGSLGDQVNVKAGYARNFLVPQGKAVPATKKNI
                     EFFEARRAELEAKLAEVLAAANARAEKINALETVTIASKAGDEGKLFGSIGTRDIADA
                     VTAAGVEVAKSEVRLPNGVLRTTGEHEVSFQVHSEVFAKVIVNVVAE"
     gene            complement(1380..1607)
                     /gene="rpsR"
                     /locus_tag="IRB70_001050"
     CDS             complement(1380..1607)
                     /gene="rpsR"
                     /locus_tag="IRB70_001050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012986941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBC0630997.1"
                     /translation="MARYFRRRKFCRFTAEGVQEIDYKDIATLKNYITESGKIVPSRI
                     TGTRAKYQRQLARAIKRARYLSLLPYTDRHQ"
     gene            complement(1612..1926)
                     /gene="priB"
                     /locus_tag="IRB70_001051"
     CDS             complement(1612..1926)
                     /gene="priB"
                     /locus_tag="IRB70_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal replication protein N"
                     /protein_id="HBC0630998.1"
                     /translation="MTNRLVLSGTVCRTPLRKVSPSGIPHCQFVLEHRSVQEEAGFHR
                     QAWCQMPVIVSGHENQAITHSITVGSRITVQGFISCHKAKNGLSKMVLHAEQIELIDS
                     GD"
     gene            complement(1933..2328)
                     /gene="rpsF"
                     /locus_tag="IRB70_001052"
     CDS             complement(1933..2328)
                     /gene="rpsF"
                     /locus_tag="IRB70_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBC0630999.1"
                     /translation="MRHYEIVFMVHPDQSEQVPGMIERYTAAITGAEGKIHRLEDWGR
                     RQLAYPINKLHKAHYVLMNVEAPQEVIDELETTFRFNDAVIRSMVMRTKHAVTEASPM
                     VKAKDERRERRDDFANETADDAEAGDSEE"
     gene            2656..2931
                     /locus_tag="IRB70_001053"
     CDS             2656..2931
                     /locus_tag="IRB70_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBC0631000.1"
                     /translation="MFSRVLALLAVLLLSANTWAAIEINNHQARNMDDVQSLGVIYIN
                     HNFATESEARQALNEETDAQGATYYHVILMREPGSNGNMHASADIYR"
     gene            complement(3060..3746)
                     /gene="ulaF"
                     /locus_tag="IRB70_001054"
     CDS             complement(3060..3746)
                     /gene="ulaF"
                     /locus_tag="IRB70_001054"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase UlaF"
                     /protein_id="HBC0631001.1"
                     /translation="MQKLKQQVFEANMELPRYGLVTFTWGNVSAIDRERGLVVIKPSG
                     VAYETMKAADMVVVDMSGKVVEGEYRPSSDTATHLELYRRYPSLGGIVHTHSTHATAW
                     AQAGLAIPALGTTHADYFFGDIPCTRGLSEEEVQGEYELNTGKVIIETLGNAEPLHTP
                     GIVVYQHGPFAWGKDAHDAVHNAVVMEEVAKMAWIARSINPQLNHIDSFLMNKHFMRK
                     HGPNAYYGQK"
     gene            complement(3746..4600)
                     /gene="ulaE"
                     /locus_tag="IRB70_001055"
     CDS             complement(3746..4600)
                     /gene="ulaE"
                     /locus_tag="IRB70_001055"
                     /EC_number="5.1.3.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase UlaE"
                     /protein_id="HBC0631002.1"
                     /translation="MLSKQIPLGIYEKALPAGECWLERLQLAKTLGFDFVEMSVDETD
                     DRLSRLDWSREQRLALVNAIVETGVRVPSMCLSAHRRFPLGSEDDAVRAQGLEIMRKA
                     IQFAQDVGIRVIQLAGYDVYYQEANNETRRRFRDGLKESVEMASRAQVTLAMEIMDYP
                     LMNSISKALGYAHYLNNPWFQLYPDIGNLSAWDNDVQMELQAGIGHIVAVHVKDTKPG
                     VFKNVPFGEGVVDFERCFETLKQSGYCGPYLIEMWSETAEDPAAEVAKARDWVKARMA
                     KAGMVEAA"
     gene            complement(4610..5260)
                     /gene="ulaD"
                     /locus_tag="IRB70_001056"
     CDS             complement(4610..5260)
                     /gene="ulaD"
                     /locus_tag="IRB70_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBC0631003.1"
                     /translation="MSLPMLQVALDNQTMDSAYETTRLIAEEVDIIEVGTILCVGEGV
                     RAVRDLKALYPHKIVLADAKIADAGKILSRMCFEANADWVTVICCADINTAKGALDVA
                     KEFNGDVQIELTGYWTWEQAQQWRDAGIQQVVYHRSRDAQAAGVAWGEADITAIKRLS
                     DMGFKVTVTGGLALEDLPLFKGIPIHVFIAGRSIRDAASPVEAARQFKRSIAELWG"
     gene            complement(5274..5738)
                     /gene="ulaC"
                     /locus_tag="IRB70_001057"
     CDS             complement(5274..5738)
                     /gene="ulaC"
                     /locus_tag="IRB70_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIA"
                     /protein_id="HBC0631004.1"
                     /translation="MKLRDSLAENKSIRLQAEAETWQDAVKIGVDLLVAADVVEPRYY
                     QAILDAVEQHGPYFVLAPGLAMPHGRPEEGVKKTGFALVTLKKPLEFNHEDNDPVDIL
                     ITMAAVDANTHQEVGIMQIVNLFEDEENFDRLRACRTEQEVLDLIDRTNAAA"
     gene            complement(5748..6053)
                     /gene="ulaB"
                     /locus_tag="IRB70_001058"
     CDS             complement(5748..6053)
                     /gene="ulaB"
                     /locus_tag="IRB70_001058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIB"
                     /protein_id="HBC0631005.1"
                     /translation="MTVRILAVCGNGQGSSMIMKMKVDQFLTQSNIDHTVNSCAVGEY
                     KSELSGADIIIASTHIAGEITVTGNKYVVGVRNMLSPADFGPKLLEVIKEHFPQDVK"
     gene            complement(6069..7466)
                     /gene="ulaA"
                     /locus_tag="IRB70_001059"
     CDS             complement(6069..7466)
                     /gene="ulaA"
                     /locus_tag="IRB70_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418614.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBC0631006.1"
                     /translation="MEILYNIFTVFFNQVMTNAPLLLGIVTCLGYILLRKSVSVIIKG
                     TIKTIIGFMLLQAGSGILTSTFKPVVAKMSEVYGINGAISDTYASMMATIDRMGDAYS
                     WVGYAVLLALALNICYVLLRRITGIRTIMLTGHIMFQQAGLIAVTLFIFGYSMWTTII
                     CTAILVSLYWGITSNMMYKPTQEVTDGCGFSIGHQQQFASWIAYKVAPFLGKKEESVE
                     DLKLPGWLNIFHDNIVSTAIVMTIFFGAILLSFGIDTVQAMAGKVNWTVYILQTGFSF
                     AVAIFIITQGVRMFVAELSEAFNGISQRLIPGAVLAIDCAAIYSFAPNAVVWGFMWGT
                     IGQLIAVGILVACGSSILIIPGFIPMFFSNATIGVFANHFGGWRAALKICLVMGMIEI
                     FGCVWAVKLTGMSAWMGMADWSILAPPMMQGFFSIGIAFMAVIIVIALAYMFFAGRAL
                     RAEEDAEKQLAEQSA"
     gene            7821..8885
                     /gene="ulaG"
                     /locus_tag="IRB70_001060"
     CDS             7821..8885
                     /gene="ulaG"
                     /locus_tag="IRB70_001060"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003856017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBC0631007.1"
                     /translation="MSKVKSITRESWILSTFPEWGSWLNEEIEQEQVAPGTFAMWWLG
                     CTGIWLKSEGGTNVCVDFWCGTGKQSHGNPLMKQGHQMQRMAGVKKLQPNLRTTPFVL
                     DPFAIRQIDAVLATHDHNDHIDVNVAAAVMQNCADDVPFIGPKTCVDLWIGWGVPKER
                     CIVVKPGDVVKVKDIEIHALDAFDRTALITLPADQKAAGVLPDGMDDRAVNYLFKTPG
                     GTLYHSGDSHYSNYYAKHGNEHQIDVALGSYGENPRGITDKMTSADILRMGEALNAKV
                     VIPFHHDIWSNFQADPQEIRVLWEMKKDRLKYGFKPFIWQVGGKFTWPLDKDNFEYHY
                     PRGFDDCFTIEPDLPFKSFL"
     gene            8993..9748
                     /gene="ulaR"
                     /locus_tag="IRB70_001061"
     CDS             8993..9748
                     /gene="ulaR"
                     /locus_tag="IRB70_001061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator UlaR"
                     /protein_id="HBC0631008.1"
                     /translation="MTEAQRHQILLEMLAQLGFVTVEKVVERLGISPATARRDINKLD
                     ESGKLKKVRNGAEAITQQRPRWTPMNLHQAQNHDEKVRIAKAASQLVNTGESVVINCG
                     STAFLLGREMCGKPVQIITNYLPLANYLIDQEHDSVIIMGGQYNKSQSITLSPQGSEN
                     SLYAGHWMFTSGKGLTAEGLYKTDMLTAMAEQKMLSVVGKLVVLVDSSKIGERAGMLF
                     SRADQIDMLITGKNANPEILQQLEAQGVSILRV"
     gene            complement(9745..10494)
                     /gene="yjfP"
                     /locus_tag="IRB70_001062"
     CDS             complement(9745..10494)
                     /gene="yjfP"
                     /locus_tag="IRB70_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBC0631009.1"
                     /translation="MIEIESRELADIPVLHAYPVGQKDTPLPCAIFYHGFTSSSLVYS
                     YFAVALAQAGLRVIMPDAPDHGSRFSGDAARRLNQFWQILLQSMQEFTTLRAAIAEEN
                     WLLDDRLAVGGASMGAMTALGITARHPTVKCTASMMGSGYFTLLARSLFPPLIPETAA
                     QQNEFNNIVAPLAEWEATNHLEQLGDRPLLLWHGLDDDVVPADESLRLQQALSETGRD
                     KLLTCSWQPGVRHRITPEALDAAVTFFRQHL"
     gene            10676..11005
                     /gene="bsmA"
                     /locus_tag="IRB70_001063"
     CDS             10676..11005
                     /gene="bsmA"
                     /locus_tag="IRB70_001063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313192.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm peroxide resistance protein BsmA"
                     /protein_id="HBC0631010.1"
                     /translation="MVSRKRNSVIYRFASLLLVLMLSACSALQGTPQPAPPVTDHPQE
                     IRRDQTQGLQRIGSVSTMVRGSPDDALAEIRAKAVAAKADYYVVVMVDETIVTGQWYS
                     QAILYRK"
     gene            11154..11429
                     /gene="yjfN"
                     /locus_tag="IRB70_001064"
     CDS             11154..11429
                     /gene="yjfN"
                     /locus_tag="IRB70_001064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418609.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease activator YjfN"
                     /protein_id="HBC0631011.1"
                     /translation="MKQLLASPSLQLVTYPASATAQSAEFASADCVTGLNEIGQISVS
                     NISGDPQDVERIVALKADEQGASWYRIITMYEDQQPDNWRVQAILYA"
     gene            complement(11546..13171)
                     /locus_tag="IRB70_001065"
     CDS             complement(11546..13171)
                     /locus_tag="IRB70_001065"
                     /EC_number="1.3.8.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418608.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isovaleryl-CoA dehydrogenase"
                     /protein_id="HBC0631012.1"
                     /translation="MHWQTHTVFNQPIPLNNSNLYLSDGALCEAVTREGAGWDSDFLA
                     SIGQQLGTAESLELGRLANVNPPELLRYDAQGRRLDDVRFHPAWHLLMQALCTNRVHN
                     LAWEEDARSGAFVARAARFMLHAQVEAGSLCPITMTFAATPLLLQMLPAPFQDWTTPL
                     LSDRYDSHLLPGGQKRGLLIGMGMTEKQGGSDVMSNTTRAERLEDGSYRLVGHKWFFS
                     VPQSDAHLVLAQTTGGLSCFFVPRFLPDGQRNAIRLERLKDKLGNRSNASCEVEFQDA
                     IGWLLGQEGEGIRLILKMGGMTRFDCALGSHAMMRRAFSLAIYHAHQRHVFGNPLIQQ
                     PLMRHVLSRMALQLEGQTALLFRLARAWDRRADAKEALWARLFTPAAKFVICKHGIPF
                     VAEAMEVLGGIGYCEESELPRLYREMPVNSIWEGSGNIMCLDVLRVLNKQAGVYDLLS
                     EAFVEVKGQDRYFDRAVRRLQQQLRKPAEELGREITHQLFLLGCGAQMLKYASPPMAQ
                     AWCQVMLDTRGGVRLSEQIQNDLLLRATGGVCL"
     gene            complement(13255..14418)
                     /locus_tag="IRB70_001066"
     CDS             complement(13255..14418)
                     /locus_tag="IRB70_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HBC0631013.1"
                     /translation="MLRHNVPVRRDLDRIAADNGFDFHIIDNEIYWDESRAYRFTLRQ
                     IEEQIEKPTAELHQMCLEVVDRAVKDEEILTQLAIPPLYWDVIAESWHARDPSLYGRM
                     DFAWCGNAPVKLLEYNADTPTSLYESAYFQWLWLEDARRSGVIPRDADQYNAIQERLI
                     SRFSELYSREPFYFCCCQDTDEDRSTVLYLQDCAQQAGQESRFIYIEDLGLGVGGVLT
                     DLDDNVIQRAFKLYPLEWMMRDDNGPLLRKRREQWVEPLWKSILSNKGLMPLLWRFFP
                     GHPNLLASWFEGEKPQIAAGESYVRKPIYSREGGNVTIFDGQNNVVDHADGDYADEPM
                     IYQAFQPLPRFGDSYTLIGSWIVDDEACGMGIREDNTLITKDTSRFVPHYIAG"
     gene            complement(14421..15059)
                     /locus_tag="IRB70_001067"
     CDS             complement(14421..15059)
                     /locus_tag="IRB70_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 domain-containing protein"
                     /protein_id="HBC0631014.1"
                     /translation="MARKRKSRNNSKIGHGAISRIGRPNNPFEPRRNRYAQKYLTLAL
                     MGGAAFFVLKGCGDSGDVDNDGDGTFYSTVQDCIDDGNNSDICAHGWNNAKAAFYADV
                     PKNMTQQNCQSKYENCYYDNVEQSWIPVVSGFLLSRVIRKDRDEPFVYNSGGSSFASR
                     PVWRNTFGDYSWRSGSGKKESYSSGGFTTKKASTVSRGGYGRSSSARGHWGG"
     gene            complement(15069..15467)
                     /locus_tag="IRB70_001068"
     CDS             complement(15069..15467)
                     /locus_tag="IRB70_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF350 domain-containing protein"
                     /protein_id="HBC0631015.1"
                     /translation="MHILDSLLAFSAYFFIGVAMVIIFLFIYSKITPHNEWQLIKNNN
                     TAASLAFSGTLLGYVIPLSSAAINAVSIPDYFAWGGIALVIQLLVFAGVRLYMPALSE
                     KIINHNTAAGMFMGTAALAGGIFNAACMTW"
     gene            complement(15485..16144)
                     /locus_tag="IRB70_001069"
     CDS             complement(15485..16144)
                     /locus_tag="IRB70_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjfK family protein"
                     /protein_id="HBC0631016.1"
                     /translation="MSGFFQRLFGKDNKPAIARGPLGLHLNSGFTLDTLAFRLLEDEL
                     LIALPGEEFTVAAVSRIDLGGGSQIFRYYTSGDEFLQINTTGGENIDDIDDIKLFVYE
                     ESYGISKESHWREAINAKAMGAITLNWQEKRWQRFFNSEEPGNIEPVYMLEKVENQNH
                     AKWEVHNFTMGYERQVTEDTCEYLLLNGEESFNDLGEPEWLFSRALGVDIPLTSLHII
                     G"
     gene            complement(16194..16892)
                     /locus_tag="IRB70_001070"
     CDS             complement(16194..16892)
                     /locus_tag="IRB70_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspA/IM30 family protein"
                     /protein_id="HBC0631017.1"
                     /translation="MGILKSLFTLGKSFISQAEESIEETQGVRMLEQHIRDAKAELDK
                     AGKSRVDLLARVKLSHDKLKDLRERKASLEARALEALSKNVNPSLINEVAEEIARLEN
                     LITAEEQVLSNLEVSRDGVEKAVTATAQRIAQFEQQMEVVKATEAMQRAQQAVTTSTV
                     GASSSVSTAAESLKRLQTRQAERQARLDAAAQLEKVADGRDLDEKLAEAGIGGSNKSI
                     AQDVLARLQRQQGE"
     gene            complement(16911..17312)
                     /locus_tag="IRB70_001071"
     CDS             complement(16911..17312)
                     /locus_tag="IRB70_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2170 family protein"
                     /protein_id="HBC0631018.1"
                     /translation="MTWNPLALATALQTVPEQNIDVTNSESALIIKMNDYGDLQINIL
                     FTSRQMIIETFICPVSSISNPDEFNTFLLRNQKMMPLSSVGISSVQQEEYYIVFGALS
                     LKSSLEDILLEITSLVDNALDLAEITEEYSH"
     gene            complement(17439..18170)
                     /gene="rlmB"
                     /locus_tag="IRB70_001072"
     CDS             complement(17439..18170)
                     /gene="rlmB"
                     /locus_tag="IRB70_001072"
                     /EC_number="2.1.1.185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBC0631019.1"
                     /translation="MSEMIYGIHAVQALLERAPERFQEVFILKGREDKRLLPLIHALE
                     SQGVVIQLANRQYLDEKSDGAVHQGIIARVKPGRQYQENDLPDLIASLDQPFLLILDG
                     VTDPHNLGACLRSADAAGVHAVIVPKDRSAQLNATAKKVACGAAESVPLIRVTNLART
                     MRMLQEENIWIVGTAGEADHTLYQSKMTGRLALVMGAEGEGMRRLTREHCDELISIPM
                     AGSVSSLNVSVATGICLFEAVRQRS"
     gene            complement(18351..20792)
                     /gene="rnr"
                     /locus_tag="IRB70_001073"
     CDS             complement(18351..20792)
                     /gene="rnr"
                     /locus_tag="IRB70_001073"
                     /EC_number="3.1.13.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418600.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBC0631020.1"
                     /translation="MSQDPFQEREAEKYANPIPSREFILEHLTKREKPASRDELAVEL
                     HIEGEEQLEGLRRRLRAMERDGQLVFTRRQCYALPERLDLVKGTVIGHRDGYGFLRVE
                     GRKDDLYLSSEQMKTCIHGDQVLAQPLGADRKGRREARIVRVLVPKTSQIVGRYFTEA
                     GVGFVVPDDSRLSFDILIPPDQIMGARMGFVVVVELTQRPTRRTKAVGKIVEVLGDNM
                     GTGMAVDIALRTHEIPYIWPQAVEQQVAGLKEEVPEEAKAGRVDLRDLPLVTIDGEDA
                     RDFDDAVYCEKKRGGGWRLWVAIADVSYYVRPPTPLDREARNRGTSVYFPSQVIPMLP
                     EVLSNGLCSLNPQVDRLCMVCEMTVSSKGRLTGYKFYEAVMSSHARLTYTKVWHILQG
                     DQDLREQYAPLVKHLEELHNLYKVLDKAREERGGISFESEEAKFIFNAERRIERIEQT
                     QRNDAHKLIEECMILANISAARFVEKAKEPALFRIHDKPSTEAITSFRSVLAELGLEL
                     PGGNKPEPRDYAELLESVADRPDAEMLQTMLLRSMKQAIYDPENRGHFGLALQSYAHF
                     TSPIRRYPDLTLHRAIKYLLAKEQGHQGNTTETGGYHYSMEEMLQLGQHCSMAERRAD
                     EATRDVADWLKCDFMLDQVGNVFKGVISSVTGFGFFVRLDDLFIDGLVHVSSLDNDYY
                     RFDQVGQRLMGESSGQTYRLGDRVEVRVEAVNMDERKIDFSLISSERAPRNVGKTARE
                     KAKKGDAGKKGGKRRQVGKKVNFEPDSAFRGEKKTKPKAAKKDARKAKKPSAKTQKIA
                     AATKAKRAAKKKVAE"
     gene            complement(20831..21256)
                     /gene="nsrR"
                     /locus_tag="IRB70_001074"
     CDS             complement(20831..21256)
                     /gene="nsrR"
                     /locus_tag="IRB70_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitric oxide-sensing transcriptional repressor
                     NsrR"
                     /protein_id="HBC0631021.1"
                     /translation="MQLTSFTDYGLRALIYMASLPEGRMTSISEVTDVYGVSRNHMVK
                     IINQLSRAGYVTAVRGKNGGIRLGKPASAIRIGDVVRELEPLSLVNCSSEFCHITPAC
                     RLKQALSKAVQSFLTELDNYTLADLVEENQPLYKLLLVE"
     gene            complement(21461..22759)
                     /gene="purA"
                     /locus_tag="IRB70_001075"
     CDS             complement(21461..22759)
                     /gene="purA"
                     /locus_tag="IRB70_001075"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBC0631022.1"
                     /translation="MGNNVVVLGTQWGDEGKGKIVDLLTERAKYVVRYQGGHNAGHTL
                     VINGEKTVLHLIPSGILRENVTSIIGNGVVLSPAALMKEMKELEDRGIPVRERLLLSE
                     ACPLILDYHVALDNAREKARGAKAIGTTGRGIGPAYEDKVARRGLRVGDLFDKETFAE
                     KLKEVMEYHNFQLVNYYKAEAVDYQKVLDDTMAVADILTSMVVDVSDLLDQARQRGDF
                     VMFEGAQGTLLDIDHGTYPYVTSSNTTAGGVATGSGLGPRYVDYVLGILKAYSTRVGA
                     GPFPTELFDETGEFLCKQGNEFGATTGRRRRTGWLDTVAVRRAVQLNSLSGFCLTKLD
                     VLDGLKEVKLCVAYRMPDGREVTTTPLAADDWKGVEPIYETMPGWSESTFGVKDRSGL
                     PQAALNYIKRIEELTGVPIDIISTGPDRTETMILRDPFDA"
     gene            complement(22863..23060)
                     /locus_tag="IRB70_001076"
     CDS             complement(22863..23060)
                     /locus_tag="IRB70_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2065 domain-containing protein"
                     /protein_id="HBC0631023.1"
                     /translation="MNSTIWLALALVLVLEGLGPMLYPKAWKKMISAMTNLPDNILRR
                     FGGGLVVAGVVVYYMLRKTIG"
     gene            complement(23142..24146)
                     /gene="hflC"
                     /locus_tag="IRB70_001077"
     CDS             complement(23142..24146)
                     /gene="hflC"
                     /locus_tag="IRB70_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease modulator HflC"
                     /protein_id="HBC0631024.1"
                     /translation="MRKSVIAIIIIVLVVLYMSVFVVKEGERGITLRFGKVLRDDDNK
                     PLVYEPGLHFKIPFIETVKMLDARIQTMDNQADRFVTKEKKDLIVDSYIKWRISDFSR
                     YYLATGGGDISQAEVLLKRKFSDRLRSEIGRLDVKDIVTDSRGRLTLEVRDALNSGSA
                     GTEDEVTTPAADNAIAEAAERVTAETKGKVPVINPNSMAALGIEVVDVRIKQINLPTE
                     VSEAIYNRMRAEREAVARRHRSQGQEEAEKLRATADYEVTRTLAEAERQGRIMRGEGD
                     AEAAKLFADAFSKDPDFYAFIRSLRAYENSFSGNQDVMVMSPDSDFFRYMKTPTSATR
                     "
     gene            complement(24149..25408)
                     /gene="hflK"
                     /locus_tag="IRB70_001078"
     CDS             complement(24149..25408)
                     /gene="hflK"
                     /locus_tag="IRB70_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsH protease activity modulator HflK"
                     /protein_id="HBC0631025.1"
                     /translation="MAWNQPGNNGQDRDPWGSSKPGGNSEGNGNKGGRDQGPPDLDDI
                     FRKLSKKLGGLGGGKGTGSGGGSSSQGPRPQLGGRVVTIAAAAIVIIWAASGFYTIKE
                     AERGVVTRFGKFSHLVEPGLNWKPTFIDEVKPVNVEAVRELAASGVMLTSDENVVRVE
                     MNVQYRVTDPEKYLYSVTSPDDSLRQATDSALRGVIGKYTMDRILTEGRTVIRSDTQR
                     ELEETIRPYDMGITLLDVNFQAARPPEEVKAAFDDAIAARENEQQYIREAEAYTNEVQ
                     PRANGQAQRILEEARAYKAQTILEAQGEVARFAKLLPEYKAAPEITRERLYIETMEKV
                     LGNTRKVLVNDKGGNLMVLPLDQMLKGGNAPAAKSDNGASNLLRLPPASSSTTSGASN
                     TSSTSQGDIMDQRRANAQRNDYQRQGE"
     gene            complement(25494..26774)
                     /gene="hflX"
                     /locus_tag="IRB70_001079"
     CDS             complement(25494..26774)
                     /gene="hflX"
                     /locus_tag="IRB70_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBC0631026.1"
                     /translation="MFDRYDAGEQAVLVHIYFTQDKDMEDLQEFESLVSSAGVEALQV
                     ITGSRKAPHPKYFVGEGKAVEIAEAVKATGASVVLFDHALSPAQERNLERLCECRVID
                     RTGLILDIFAQRARTHEGKLQVELAQLRHLATRLVRGWTHLERQKGGIGLRGPGETQL
                     ETDRRLLRNRIVQIQSRLERVEKQREQGRQSRIKADVPTVSLVGYTNAGKSTLFNRIT
                     EARVYAADQLFATLDPTLRRIDVADVGETVLADTVGFIRHLPHDLVAAFKATLQETRQ
                     ATLLLHVIDAADVRVQENIEAVNTVLEEIDAHEIPTLLVMNKIDMLDDFEPRIDRDEE
                     NKPIRVWLSAQTGAGIPQLFQALTERLSGEVAQHTLRLPPQEGRLRSRFYQLQAIEKE
                     WMEEDGSVSLQVRMPIVDWRRLCKQEPALIDYLI"
     gene            complement(26850..27158)
                     /gene="hfq"
                     /locus_tag="IRB70_001080"
     CDS             complement(26850..27158)
                     /gene="hfq"
                     /locus_tag="IRB70_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone Hfq"
                     /protein_id="HBC0631027.1"
                     /translation="MAKGQSLQDPFLNALRRERVPVSIYLVNGIKLQGQIESFDQFVI
                     LLKNTVSQMVYKHAISTVVPSRPVSHHSNNAGGGTSSNYHHGSSAQNTSAQQDSEETE
                     "
     gene            complement(27244..28194)
                     /gene="miaA"
                     /locus_tag="IRB70_001081"
     CDS             complement(27244..28194)
                     /gene="miaA"
                     /locus_tag="IRB70_001081"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBC0631028.1"
                     /translation="MSDISKASLPKAIFLMGPTASGKTALAIELRKILPVELISVDSA
                     LIYKGMDIGTAKPNAEELLAAPHRLLDIRDPSQAYSAADFRRDALAEMADITAAGRIP
                     LLVGGTMLYFKALLEGLSPLPSADPEVRARIEQQAAEQGWESLHRQLQEIDPVAAARI
                     HPNDPQRLSRALEVFFISGKTLTELTQTSGDALPYQVHQFAIAPASRELLHQRIEQRF
                     HQMLASGFEAEVRALFARGDLHTDLPSIRCVGYRQMWSYLEGEISYDEMVYRGVCATR
                     QLAKRQITWLRGWEGVHWLDSEKPEQARDEVLQVVGAIAG"
     gene            complement(28187..30034)
                     /gene="mutL"
                     /locus_tag="IRB70_001082"
     CDS             complement(28187..30034)
                     /gene="mutL"
                     /locus_tag="IRB70_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313173.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBC0631029.1"
                     /translation="MPIQVLPPQLANQIAAGEVVERPASVVKELVENSLDAGATRIDI
                     DIERGGAKLIRIRDNGCGIKKDELALALARHATSKIASLDDLEAIISLGFRGEALASI
                     SSVSRLTLTSRTAEQQEAWQAYAEGRDMDVTVKPAAHPVGTTLEVLDLFYNTPARRKF
                     LRTEKTEFNHIDEIIRRIALARFDVTINLSHNGKIVRQYRAVPEGGQKERRLGAICGT
                     AFLEQALAIEWQHGDLSLRGWVADPNHTTPALAEIQYCYVNGRMMRDRLINHAIRQAC
                     EDKLGADQQPAFVLYLEIDPHQVDVNVHPAKHEVRFHQSRLVHDFIYQGVLSVLQQQL
                     ETPLPLDDEPQPAPRAIPENRVAAGRNHFAEPAVREPVAPRYTPAPSSGSRPAAPWPN
                     AQPGYQKQQGEVYRQLLQTPAPMPKPKAPEPQEPALAANSQSFGRVLTIVHSDCALLE
                     RDGNISLLALPVAERWLRQAQLTPGEAPVCAQPLLIPLRLKVSGEEKSALEKAQSALA
                     ELGIDFQSDAQHVTIRAVPLPLRQQNLQILIPELIGYLAKQSVFEPGNIAQWIARNLM
                     SEHAQWSMAQAITLLADVERLCPQLVKTPPGGLLQSVDLHPAIKALKDE"
     gene            complement(30044..31381)
                     /gene="amiB"
                     /locus_tag="IRB70_001083"
     CDS             complement(30044..31381)
                     /gene="amiB"
                     /locus_tag="IRB70_001083"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiB"
                     /protein_id="HBC0631030.1"
                     /translation="MMYRIRKWLVATLLLLCAQVGAATLSDIQVSNGNQQARITLSFI
                     GDPDYAFSHQSKRTVALDIKQTGVIQGLPLLFSGNNLVKAIRSGTPKDAQTLRLVVDL
                     TENGKTEAVKRQNGSNYTVVFTINADAPPPPPPPPVVAKRVETPAVVAPRVSEPARNP
                     FKTESNRTTGVISSNTVTRPAARATANIGDKIIIAIDAGHGGQDPGAIGPGGTREKNV
                     TIAIARKLRTLLNDDPMFKGVLTRDGDYFISVMGRSDVARKQNANFLVSIHADAAPNR
                     SATGASVWVLSNRRANSEMASWLEQHEKQSELLGGAGDVLANSQSDPYLSQAVLDLQF
                     GHSQRVGYDVATSMISQLQRIGEIHKRRPEHASLGVLRSPDIPSVLVETGFISNNSEE
                     RLLASDDYQQQLAEAIYKGLRNYFLAHPMQSAPQGATAQTASTVTTPDRTLPN"
     gene            complement(31400..31861)
                     /gene="tsaE"
                     /locus_tag="IRB70_001084"
     CDS             complement(31400..31861)
                     /gene="tsaE"
                     /locus_tag="IRB70_001084"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBC0631031.1"
                     /translation="MMNRVIPLPDEQATLDLGERVAKACDGATVIYLYGDLGAGKTTF
                     SRGFLQALGHQGNVKSPTYTLVEPYTLDNLMVYHFDLYRLADPEELEFMGIRDYFAND
                     AICLVEWPQQGTGVLPDPDVEIHIDYQAQGREARVSAVSSAGELLLARLAG"
     gene            complement(31833..33380)
                     /gene="nnr"
                     /locus_tag="IRB70_001085"
     CDS             complement(31833..33380)
                     /gene="nnr"
                     /locus_tag="IRB70_001085"
                     /EC_number="4.2.1.136"
                     /EC_number="5.1.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional ADP-dependent NAD(P)H-hydrate
                     dehydratase/NAD(P)H-hydrate epimerase"
                     /protein_id="HBC0631032.1"
                     /translation="MTDHTMKKNPISIPHTVWYADDIRRGEREAADALGLTLYELMLR
                     AGEAAFQVCRSAYPDARHWLVLCGHGNNGGDGYVVARLAKAVGIDVTLLAQESDKPLP
                     EEAALAREAWLNAGGEIHASNIVWPESVDLIVDALLGTGLQQAPRESISQLIDHANSH
                     PAPIVAVDIPSGLLAETGATPGAVINADHTITFIALKPGLLTGKARDVTGQLHFDSLG
                     LDSWLAGQETKIQRFSAEQLSHWLKPRRPTSHKGDHGRLVIIGGDHGTAGAIRMTGEA
                     ALRAGAGLVRVLTRSENIAPLLTARPELMVHELTMDSLTESLEWADVVVIGPGLGQQE
                     WGKKALQKVENFRKPMLWDADALNLLAINPDKRHNRVITPHPGEAARLLGCSVAEIES
                     DRLHCAQRLVQRYGGVAVLKGAGTVVAAHSDALGIIDVGNAGMASGGMGDVLSGIIGA
                     LLGQKMSPYDAACAGCVAHGAAADVLAARFGTRGMLATDLFSTLQRIVNPEVTDKNHD
                     ESSNSAP"
     gene            33379..34518
                     /gene="queG"
                     /locus_tag="IRB70_001086"
     CDS             33379..34518
                     /gene="queG"
                     /locus_tag="IRB70_001086"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313170.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBC0631033.1"
                     /translation="MSEPLDLNQLAQKIKQWGLELGFQQVGITDTDLSASEPKLQAWL
                     DKQYHGEMDWMARHGMLRARPHELLPGTLRVISVRMNYLPANAAFASTLKNPKLGYVS
                     RYALGRDYHKLLRNRLKKLGEMIQQHCVSLNFRPFVDSAPILERPLAEKAGLGWTGKH
                     SLILNREAGSFFFLGELLVDIPLPVDQPVEEGCGKCVACMTICPTGAIVEPYTVDARR
                     CISYLTIELEGAIPVELRPLMGNRIYGCDDCQLICPWNRYSQLTTEDDFSPRKPLHAP
                     ELIELFAWSEEKFLKVTEGSAIRRIGHLRWLRNIAVALGNAPWDETILAALESRKGEH
                     PLLDEHIAWAIAQQIERRNASIVEVQLPKKQRLVRVIEKGLPRDA"
     gene            complement(34501..34554)
                     /locus_tag="IRB70_001087"
     CDS             complement(34501..34554)
                     /locus_tag="IRB70_001087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631034.1"
                     /translation="MRFYFYSQAVDESGVTR"
     gene            complement(34788..34863)
                     /locus_tag="IRB70_001088"
     tRNA            complement(34788..34863)
                     /locus_tag="IRB70_001088"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(34828..34830),aa:Gly,seq:gcc)
     gene            complement(35074..35619)
                     /gene="orn"
                     /locus_tag="IRB70_001089"
     CDS             complement(35074..35619)
                     /gene="orn"
                     /locus_tag="IRB70_001089"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoribonuclease"
                     /protein_id="HBC0631035.1"
                     /translation="MSANENNLIWIDLEMTGLDPERDRIIEIATLVTDANLNILAEGP
                     TIAVHQSDEQLALMDDWNVRTHTASGLVERVKASTMGDREAELATLEFLKQWVPAGKS
                     PICGNSIGQDRRFLFKYMPELEAYFHYRYLDVSTLKELARRWKPEILDGFTKQGTHQA
                     MDDIRESVAELAYYREHFIKL"
     gene            35714..36766
                     /gene="rsgA"
                     /locus_tag="IRB70_001090"
     CDS             35714..36766
                     /gene="rsgA"
                     /locus_tag="IRB70_001090"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313167.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small ribosomal subunit biogenesis GTPase RsgA"
                     /protein_id="HBC0631036.1"
                     /translation="MSKNKLSKGQQRRVNANHQRRLKTSKEKPDYDDNLFGEPDEGIV
                     ISRFGMHADVESADGDVHRCNIRRTIRSLVTGDRVVWRPGKPAAEGVNVKGIVEAVHE
                     RTSVLTRPDFYDGVKPIAANIDQIVIVSAILPELSLNIIDRYLVACETLQIEPIIVLN
                     KIDLLDDEGMKFVNEQMDIYRNIGYRVLMVSSHTQDGLKPLEEALTGRISIFAGQSGV
                     GKSSLLNALLGLQKEILTNDVSDNSGLGQHTTTAARLYHFPHGGDVIDSPGVREFGLW
                     HLEPEQITQGFVEFHDYLGLCKYRDCKHDTDPGCAIREAVEEGKIAETRFENYHRILE
                     SMAQVKTRKNFSDTDD"
     gene            36862..37830
                     /gene="psd"
                     /locus_tag="IRB70_001091"
     CDS             36862..37830
                     /gene="psd"
                     /locus_tag="IRB70_001091"
                     /EC_number="4.1.1.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313166.1"
                     /note="Phosphatidylserine decarboxylase is synthesized as
                     a single chain precursor. Generation of the pyruvoyl
                     active site from a Ser is coupled to cleavage of a Gly-Ser
                     bond between the larger (beta) and smaller (alpha chains).
                     It is an integral membrane protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylserine decarboxylase"
                     /protein_id="HBC0631037.1"
                     /translation="MLNSFKLSLQYILPKLWLTRLAGWGASKRAGWLTKLVIDLFVKY
                     YKVDMKEAQKPDTASYRTFNEFFVRPLRDEVRPIDTDPNVLVMPADGVISQLGKIEED
                     KILQAKGHNYSLEALLAGNYLMADLFRNGTFVTTYLSPRDYHRVHMPCNGILREMIYV
                     PGDLFSVNHLTAQNVPNLFARNERVICLFDTEFGPMAQILVGATIVGSIETVWAGTIT
                     PPREGIIKRWTWPAGENDGSVALLKGQEMGRFKLGSTVINLFAPGKVNLVEQLESLSV
                     TKIGQPLAVSTETFVTPDAEPAPLPAEEIEAEHDASPLVDDKKDQV"
     gene            37852..41175
                     /gene="mscM"
                     /locus_tag="IRB70_001092"
     CDS             37852..41175
                     /gene="mscM"
                     /locus_tag="IRB70_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="miniconductance mechanosensitive channel MscM"
                     /protein_id="HBC0631038.1"
                     /translation="MRLIITFLMAWCLSWGAYAATAPDSKQISQELEQAKAAKPAQPE
                     VVEALQSALNALEERKGSLERIKQYQEVIDNYPKLSATLRAQLNNMRDEPRSVSPGMS
                     TDALNQEILQVSSQLLDKSRQAQQEQERAREIADSLNQLPQQQTDARRQLNEIERRLG
                     TLTGNSPLNQAQNFALQSDSARLKALVDELELAQLSANNRQELARLRSELAEKESQQL
                     DAYLQALRNQLNSQRQLEAERALESTELLAENSADLPKDIVAQFKINRELSAALNQQA
                     QRMDLVASQQRQAASQTLQVRQALNTLREQSQWLGSSNLLGEALRAQVARLPEMPKPQ
                     QLDTEMAQLRVQRLRYEDLLNKQPQLRQIHQADGQPLTAEQNRILEAQLRTQRELLNS
                     LLQGGDTLLLELTKLKVSNGQLEDALKEVNEATHRYLFWTSDVRPMTIAWPLEIAQDL
                     RRLISLDTFSQLGKASVMMLTSKETILPLFGALILVGCSIYSRRYFTRFLERSAAKVG
                     KVTQDHFWLTLRTLFWSILVASPLPVLWMTLGYGLREAWPYPLAVAIGDGVTATVPLL
                     WVVMICATFARPNGLFIAHFGWPRERVSRGMRYYLMSIGLIVPLIMALMMFDNLDDRE
                     FSGSLGRLCFILICGALAVVTLSLKKAGIPLYLNKEGSGDNITNHMLWNMMISAPLVA
                     ILASAVGYLATAQALLARLETSVAIWFLLLVVYHVIRRWMLIQRRRLAFDRAKHRRAE
                     MLAQRARGEEEAHHHSSPEGAIEVDESEVDLDAISAQSLRLVRSILMLIALLSVIVLW
                     SEIHSAFGFLENISLWDVTSTVQGVESLEPITLGAVLIAILVFIITTQLVRNLPALLE
                     LAILQHLDLTPGTGYAITTITKYLLMLIGGLVGFSMIGIEWSKLQWLVAALGVGLGFG
                     LQEIFANFISGLIILFEKPIRIGDTVTIRDLTGSVTKINTRATTISDWDRKEIIVPNK
                     AFITEQFINWSLSDSVTRVVLTIPAPADANSEEVTEILLTAARRCSLVIDNPAPEVFL
                     VDLQQGIQIFELRIYAAEMGHRMPLRHEIHQLILAGFHAHGIDMPFPPFQMRLESLNG
                     KQTGRTLTSAGKGRQAGSL"
     gene            complement(41326..42828)
                     /gene="yjeM"
                     /locus_tag="IRB70_001093"
     CDS             complement(41326..42828)
                     /gene="yjeM"
                     /locus_tag="IRB70_001093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418580.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/gamma-aminobutyrate family transporter
                     YjeM"
                     /protein_id="HBC0631039.1"
                     /translation="MPHTIKKMSLIGLILMIFTSVFGFANSPSAYYLMGYSAIPFYIF
                     SALLFFIPFALMMAEMGAAYRKEEGGIYSWMNNSVGPRFAFIGTFMWFSSYIIWMVST
                     SAKVWVPFSTFLYGSDMTQHWHIAGLEPTQVVGLLAVAWMILVTVVASKGINKIARIT
                     AVGGIAVMCLNLVLLLVSITILLLNGGHFAQDINFLTSPNPGYQSGLAMLSFVVFAIF
                     AYGGIEAVGGLVDKTENPEKNFAKGIVFAAIVISIGYSLAIFLWGVSTNWQQVLSNGS
                     VNLGNITYVLMKSLGVTLGNALHLSPEASLSLGVWFARITGLSMFLAYTGAFFTLCYS
                     PLKAIIQGTPKALWPEPMTRLNAMGMPSIAMWMQCGLVTVFILLVSFGGGTASAFFNK
                     LTLMANVSMTLPYLFLALAFPFFKARQDLDRPFVIFKTHLSAMIATVVVVLVVTFANV
                     FTIIQPVVEAGDWDSTLWMIGGPVFFSLLAMAIYQNYCSRMANKPELALD"
     gene            complement(43047..44024)
                     /gene="epmA"
                     /locus_tag="IRB70_001094"
     CDS             complement(43047..44024)
                     /gene="epmA"
                     /locus_tag="IRB70_001094"
                     /EC_number="6.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P--(R)-beta-lysine ligase"
                     /protein_id="HBC0631040.1"
                     /translation="MSETASWQPSASIPNLLKRAAIMAEIRRFFADRGVLEVETPCMS
                     QATVTDIHLVPFETRFVGPGHSQGMNLWLMTSPEYHMKRLLVAGCGPVFQLCRSFRNE
                     EMGRYHNPEFTMLEWYRPHYDMYRLMNEVDDLLQQVLDCPAAESLSYQQAFLRYLEID
                     PLSADKTQLREVAAKLDLSNVADTEEDRDTLLQLLFTFGVEPNIGKEKPTFVYHFPAS
                     QASLAQISTEDHRVAERFEVYYKGIELANGFHELTDAREQQQRFEQDNRKRAARGLPQ
                     HPIDQNLIEALKVGMPDCSGVALGVDRLVMLALGAETLAEVIAFSVDRA"
     gene            44349..46157
                     /gene="frdA"
                     /locus_tag="IRB70_001095"
     CDS             44349..46157
                     /gene="frdA"
                     /locus_tag="IRB70_001095"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase (quinol) flavoprotein
                     subunit"
                     /protein_id="HBC0631041.1"
                     /translation="MQTFQADLAIVGAGGAGLRAAIAAAQANPNAKIALISKVYPMRS
                     HTVAAEGGSAAVAQDHDSFEYHFHDTVAGGDWLCEQDVVDYFVHHCPTEMTQLELWGC
                     PWSRRPDGSVNVRRFGGMKIERTWFAADKTGFHMLHTLFQTSLQFPQIQRFDEHFVLD
                     ILVDDGHVRGLVAMNMMEGTLVQIRANAVVMATGGAGRVYRYNTNGGIVTGDGMGMAL
                     SHGVPLRDMEFVQYHPTGLPGSGILMTEGCRGEGGILVNKNGYRYLQDYGMGPETPLG
                     EPKNKYMELGPRDKVSQAFWHEWRKGNTISTPRGDVVYLDLRHLGEKKLHERLPFICE
                     LAKAYVGVDPVKEPIPVRPTAHYTMGGIETDQNCETRIKGLFAVGECSSVGLHGANRL
                     GSNSLAELVVFGRLAGEQAMERASTAGNGNEAAIEAQAAGVEQHLKDLVNQDGGENWA
                     KIRDEMGMAMEEGCGIYRTPELMQKTIDKLAELQERFKRVRITDTSSVFNTDLLYTIE
                     LGHGLNVAECMAHSAMARKESRGAHQRLDEGCTERDDVNFLKHTLAFRDADGTTRLEY
                     SDVKITTLPPAKRVYGGEADAADKAEAANKKEKANG"
     gene            46150..46884
                     /gene="frdB"
                     /locus_tag="IRB70_001096"
     CDS             46150..46884
                     /gene="frdB"
                     /locus_tag="IRB70_001096"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HBC0631042.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            46895..47290
                     /gene="frdC"
                     /locus_tag="IRB70_001097"
     CDS             46895..47290
                     /gene="frdC"
                     /locus_tag="IRB70_001097"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HBC0631043.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            47301..47660
                     /gene="frdD"
                     /locus_tag="IRB70_001098"
     CDS             47301..47660
                     /gene="frdD"
                     /locus_tag="IRB70_001098"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HBC0631044.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            47723..48856
                     /locus_tag="IRB70_001099"
     CDS             47723..48856
                     /locus_tag="IRB70_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HBC0631045.1"
                     /translation="MFKTTLCTLLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMKTRVFQPLKLNHTWINVLSAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPFDINEKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPLNPDIIINGSDNKIALAARPVKPITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ"
     gene            48945..49478
                     /gene="blc"
                     /locus_tag="IRB70_001100"
     CDS             48945..49478
                     /gene="blc"
                     /locus_tag="IRB70_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin Blc"
                     /protein_id="HBC0631046.1"
                     /translation="MRLLPLVAAATAAFLVVACSSPTPPRGVTVVNNFDAKRYLGTWY
                     EIARFDHRFERGLEKVTATYSLRDDGGLNVINKGYNPDRGMWQQSEGKAYFTGAPTRA
                     ALKVSFFGPFYGGYNVIALDREYRHALVCGPDRDYLWILSRTPTISDEVKQEMLAVAT
                     REGFDVSKFIWVQQPGS"
     gene            complement(49475..49792)
                     /gene="sugE"
                     /locus_tag="IRB70_001101"
     CDS             complement(49475..49792)
                     /gene="sugE"
                     /locus_tag="IRB70_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418572.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter SugE"
                     /protein_id="HBC0631047.1"
                     /translation="MSWIILVIAGLLEVVWAVGLKYTHGFSRLTPSVITVTAMIVSMA
                     LLAWAMKSLPVGTAYAVWTGIGAVGAAITGIVLLGESANPMRLASLALIVLGIIGLKL
                     STH"
     gene            complement(49968..50114)
                     /gene="ecnB"
                     /locus_tag="IRB70_001102"
     CDS             complement(49968..50114)
                     /gene="ecnB"
                     /locus_tag="IRB70_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein toxin entericidin B"
                     /protein_id="HBC0631048.1"
                     /translation="MVKKTIAAIFSVLVLSTVLTACNTTRGVGEDISDGGNAISGAAT
                     KAQQ"
     gene            complement(50225..50350)
                     /gene="ecnA"
                     /locus_tag="IRB70_001103"
     CDS             complement(50225..50350)
                     /gene="ecnA"
                     /locus_tag="IRB70_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein antitoxin entericidin A"
                     /protein_id="HBC0631049.1"
                     /translation="MMKRLIVLVLLASALLTGCNTARGFGEDIKHLGNSISRAAS"
     gene            complement(50402..50968)
                     /gene="efp"
                     /locus_tag="IRB70_001104"
     CDS             complement(50402..50968)
                     /gene="efp"
                     /locus_tag="IRB70_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004871142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBC0631050.1"
                     /translation="MATYYSNDFRAGLKIMLDGEPYAVEASEFVKPGKGQAFARVKLR
                     RLLTGTRVEKTFKSTDSAEGADVVDMNLTYLYNDGEFWHFMNNETFEQLSADAKAIGD
                     NAKWLLDQAECIVTLWNGQPISVTPPNFVELEIVDTDPGLKGDTAGTGGKPATLSTGA
                     VVKVPLFVQIGEVIKVDTRSGEYVSRVK"
     gene            51010..52038
                     /gene="epmB"
                     /locus_tag="IRB70_001105"
     CDS             51010..52038
                     /gene="epmB"
                     /locus_tag="IRB70_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF-P beta-lysylation protein EpmB"
                     /protein_id="HBC0631051.1"
                     /translation="MAHIVTLNTPSREDWLTQLADVVTDPDELLRLLNIDADEKLLAG
                     RSAKKLFALRVPRSFIDRMEKGDPDDPLLRQVLTSQDEFVVAPGFSTDPLEEQHSVVP
                     GLLHKYHNRALLLVKGGCAVNCRYCFRRHFPYAENQGNKRNWQTALEYVAAHPELDEM
                     IFSGGDPLMAKDHELDWLLTQLEAIPHIKRLRIHSRLPIVIPARITDALVERFSHSTL
                     QILLVNHINHANEVDETFRQAMAKLRRVGVTLLNQSVLLRGVNDNAQTLANLSNALFD
                     AGVMPYYLHVLDKVQGAAHFMVSDDEARQIMRELLTLVSGYLVPKLAREIGGEPSKTP
                     LDLQLRQQ"
     gene            52273..53142
                     /locus_tag="IRB70_001106"
     CDS             52273..53142
                     /locus_tag="IRB70_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjeJ family protein"
                     /protein_id="HBC0631052.1"
                     /translation="MAISIKGVNTGVIRKSNNFIALALKIKEPRNKESLFFLSVMELR
                     DLLIALESRLHQKHKLDAAARLQYEQARDKVIKKMAENIPEILVDELKNADINRRVNT
                     LELNDNQGENLTFVLTLHDGSKCELVINELQIEMLARAIIHAINNAEMRELALRITSL
                     LDFLPLYDVDCQDNGNLEYDTYSQPEWKHNLFNHYLAVLYRFKDESGKEQFSGAVVKT
                     REATPGKEVEAITRRMLDFSPRLKKLAGVPCQVYVRTVAANNAQPLTQDQCLRALHHL
                     RVQSTSKTAPQAK"
     gene            complement(53192..53545)
                     /locus_tag="IRB70_001107"
     CDS             complement(53192..53545)
                     /locus_tag="IRB70_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4156 domain-containing protein"
                     /protein_id="HBC0631053.1"
                     /translation="MHVKYLAGIVGAALLMAGCSSSNELSAAGQSVRIVDEQPGAECQ
                     LIGTATGKQSNWLSGQHGEEGGSMRGAANDLRNQAAAMGGNVIYGISSPSQGMLSSFV
                     PTDSQIIGQVYKCPN"
     gene            complement(53680..55326)
                     /gene="groL"
                     /locus_tag="IRB70_001108"
     CDS             complement(53680..55326)
                     /gene="groL"
                     /locus_tag="IRB70_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120975.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBC0631054.1"
                     /translation="MAAKDVKFGNDARVKMLRGVNVLADAVKVTLGPKGRNVVLDKSF
                     GAPTITKDGVSVAREIELEDKFENMGAQMVKEVASKANDAAGDGTTTATVLAQAIITE
                     GLKAVAAGMNPMDLKRGIDKAVTAAVEELKALSVPCSDSKAIAQVGTISANSDETVGK
                     LIAEAMDKVGKEGVITVEDGTGLQDELDVVEGMQFDRGYLSPYFINKPETGAVELESP
                     FILLADKKISNIREMLPVLEAVAKAGKPLLIIAEDVEGEALATLVVNTMRGIVKVAAV
                     KAPGFGDRRKAMLQDIATLTGGTVISEEIGMELEKATLEDLGQAKRVVINKDTTTIID
                     GVGEEAAIQGRVAQIRQQIEEATSDYDREKLQERVAKLAGGVAVIKVGAATEVEMKEK
                     KARVEDALHATRAAVEEGVVAGGGVALIRVASKLADLRGQNEDQNVGIKVALRAMEAP
                     LRQIVLNCGEEPSVVANTVKGGDGNYGYNAATEEYGNMIDMGILDPTKVTRSALQYAA
                     SVAGLMITTECMVTDLPKNDAADLGAAGGMGGMGGMGGMM"
     gene            complement(55370..55663)
                     /locus_tag="IRB70_001109"
     CDS             complement(55370..55663)
                     /locus_tag="IRB70_001109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000027827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBC0631055.1"
                     /translation="MNIRPLHDRVIVKRKEVETKSAGGIVLTGSAAAKSTRGEVLAVG
                     NGRILENGEVKPLDVKVGDIVIFNDGYGVKSEKIDNEEVLIMSESDILAIVEA"
     gene            55939..57195
                     /gene="yjeH"
                     /locus_tag="IRB70_001110"
     CDS             55939..57195
                     /gene="yjeH"
                     /locus_tag="IRB70_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine/branched-chain amino acid
                     transporter"
                     /protein_id="HBC0631056.1"
                     /translation="MSGLKQELGLAQGIGLLSTSLLGTGVFAVPALAALVAGNNSLWA
                     WPVLIILVFPIAIVFAILGRHYPSAGGVAHFVGMAFGSRLERVTGWLFLSVIPVGLPA
                     ALQIAAGFGQAMFGWHSWQLLLAELGTLALVWYIGTRGASSSANLQTVIAGLIVALIV
                     AIWWAGDIKPANIPFPAPGNIELTGLFAALSVMFWCFVGLEAFAHLASEFKNPERDFP
                     RALMIGLLLAGLVYWGCTVVVLHFDAYGEQMAAAASLPKIVVLLFGVGALWIACVIGY
                     LACFASLNIYIQSFARLVWSQAQHNPDHYLARLSSRHIPNNALNAVLGCCVVSTLVIH
                     ALEINLDALIIYANGIFIMIYLLCMLAGCKLLQGRYRLLAVVGGLLCVLLLAMVGWKS
                     LYALIMLAGLWLFLPKRKTPENGIIT"
     gene            complement(57211..57687)
                     /gene="fxsA"
                     /locus_tag="IRB70_001111"
     CDS             complement(57211..57687)
                     /gene="fxsA"
                     /locus_tag="IRB70_001111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418564.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein FxsA"
                     /protein_id="HBC0631057.1"
                     /translation="MRWLPFIAIFLYVYIEISIFIQVAHVLGVLLTLVLVIFTSVIGM
                     SLVRNQGFKNFVLMQQKMAAGENPAAEMIKSVSLIIAGLLLLLPGFFTDFLGLLLLLP
                     PVQKHLTVKLMPHLRFSRMPGGGFSAGTGGGNTFDGEYQRKDDERDRLDHKDDRQD"
     gene            58024..59460
                     /gene="aspA"
                     /locus_tag="IRB70_001112"
     CDS             58024..59460
                     /gene="aspA"
                     /locus_tag="IRB70_001112"
                     /EC_number="4.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313147.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate ammonia-lyase"
                     /protein_id="HBC0631058.1"
                     /translation="MSNNIRIEEDLLGTREVPADAYYGVHTLRAIENFYISNNKISDI
                     PEFVRGMVMVKKAAAMANKELQTIPKSVANAIIAACDEVLNNGKCMDQFPVDVYQGGA
                     GTSVNMNTNEVLANIGLELMGHQKGEYQYLNPNDHVNKCQSTNDAYPTGFRIAVYSSL
                     IKLVDAINQLREGFERKAVEFQDILKMGRTQLQDAVPMTLGQEFRAFSILLKEEVKNI
                     QRTAELLLEVNLGATAIGTGLNTPKEYSPLAVKKLAEVTGFPCVPAEDLIEATSDCGA
                     YVMVHGALKRLAVKMSKICNDLRLLSSGPRAGLNEINLPELQAGSSIMPAKVNPVVPE
                     VVNQVCFKVIGNDTTVTMAAEAGQLQLNVMEPVIGQAMFESVHILTNACYNLLEKCIN
                     GITANKEVCEGYVYNSIGIVTYLNPFIGHHNGDIVGKICAETGKSVREVVLERGLLTE
                     AELDDIFSVQNLMHPAYKAKRYTDESEQ"
     gene            59578..60879
                     /gene="dcuA"
                     /locus_tag="IRB70_001113"
     CDS             59578..60879
                     /gene="dcuA"
                     /locus_tag="IRB70_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuA"
                     /protein_id="HBC0631059.1"
                     /translation="MLVVELIIVLLAIFLGARLGGIGIGFAGGLGVLVLAAIGVKPGN
                     IPFDVISIIMAVIAAISAMQVAGGLDYLVHQTEKLLRRNPKYITILAPIVTYFLTIFA
                     GTGNISLATLPVIAEVAKEQGVKPCRPLSTAVVSAQIAITASPISAAVVYMSSVMEGH
                     GISYLHLLSVVIPSTLLAVLVMSFLVTMLFNSKLSDDPIYRKRLEEGLVELRGEKQIE
                     IKSGAKTSVWLFLLGVVGVVIYAIINSPSMGLVEKPLMNTTNAILIIMLSVATLTTVI
                     CKVDTDNILNSSTFKAGMSACICILGVAWLGDTFVSNNIDWIKDTAGEVIQGHPWLLA
                     VIFFFASALLYSQAATAKALMPMALALNVSPLTAVASFAAVSGLFILPTYPTLVAAVQ
                     MDDTGTTRIGKFVFNHPFFIPGTLGVALAVCFGFVLGSFML"
     gene            60995..61333
                     /gene="cutA"
                     /locus_tag="IRB70_001114"
     CDS             60995..61333
                     /gene="cutA"
                     /locus_tag="IRB70_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HBC0631060.1"
                     /translation="MLDEKSSNTASVVVLCTAPDEATAQDLAAKVLAEKLAACATLIP
                     GATSLYYWEGKLEQEYEVQMILKTTVSHQQALLECLKSHHPYQTPELLVLPVTHGDTD
                     YLSWLNASLR"
     gene            61309..63006
                     /gene="dsbD"
                     /locus_tag="IRB70_001115"
     CDS             61309..63006
                     /gene="dsbD"
                     /locus_tag="IRB70_001115"
                     /EC_number="1.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD"
                     /protein_id="HBC0631061.1"
                     /translation="MAQRIFTLILLLCSTSVFAGLFDAPRRSQFVPADQAFAFDFQQN
                     QHDLNLTWQIKDGYYLYRKQIRITPEHAKIADVQLPQGVWHEDEFYGKSEIYRDRLTL
                     PVTINQASAGATLTVTYQGCADAGFCYPPETKTVPLSEVVANNAASQPVSVPQQEQHT
                     AQLPFSALWALLIGIGIAFTPCVLPMYPLISGIVLGGKQRLSTARALLLTFIYVQGMA
                     LTYTALGLVVAAAGLQFQAALQHPYVLIGLAIVFTLLAMSMFGLFTLQLPSSLQTRLT
                     LMSNRQQGGSPGGVFVMGAIAGLICSPCTTAPLSAILLYIAQSGNMWLGGGTLYLYAL
                     GMGLPLMLITVFGNRLLPKSGPWMEQVKTAFGFVILALPVFLLERVIGDIWGLRLWSA
                     LGVAFFGWAFITSLQAKRGWMRVVQIILLAAALVSVRPLQDWAFGATHTVQTQTHLNF
                     TQIKTVDELNQALVEAKGKPVMLDLYADWCVACKEFEKYTFSDPQVQKALADTVLLQA
                     NVTANDAQDVALLKHLNVLGLPTILFFDGQGQEHPQERVTGFMDAETFSAHLRDRQP"
     gene            63043..63618
                     /locus_tag="IRB70_001116"
     CDS             63043..63618
                     /locus_tag="IRB70_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBC0631062.1"
                     /translation="MQREDVLGEALKLLELQGIANTTLEMVAERVDYPLDELRRFWPD
                     KEAILYDALRYLSQQIDVWRRQLMLDETQTAEQKLLARYQALSECVKNNRYPGCLFIA
                     ACTFYPDPGHPIHQLADQQKSAAYDFTHELLTTLEVDDPAMVAKQMELVLEGCLSRML
                     VNRSQADVDTAHRLAEDILRFARCRQGGALT"
     gene            63725..63800
                     /locus_tag="IRB70_001117"
     tRNA            63725..63800
                     /locus_tag="IRB70_001117"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:63758..63760,aa:Phe,seq:gaa)
     gene            63998..65263
                     /locus_tag="IRB70_001118"
     CDS             63998..65263
                     /locus_tag="IRB70_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HBC0631063.1"
                     /translation="MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRI
                     LGKEKTLALGVYPEVSLSEARTKRDEARKLILEGIDPCEQKRAKKVVPDLQLSFEHIA
                     RRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLNTPDLLIPVRAAEDKQIYEI
                     ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELLSRIDS
                     YKGQPVTRLAVMLNLLVFIRSSELRYARWSEIDIENAMWTIPAEREPLPGVKYSHRGS
                     KMRTPHLVPLSKQAVAILTELQTWAGENGLVFTGAHDPHKPISENTVNKALRVMGYDT
                     TLDICGHGFRTMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLML
                     QWWADFLNANRERFISPFEYAKINNPLKQ"
     gene            complement(65585..67084)
                     /locus_tag="IRB70_001119"
     CDS             complement(65585..67084)
                     /locus_tag="IRB70_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001535067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HBC0631064.1"
                     /translation="MNIRKLFYTDNISRILLFLFFPGMCVITTAACGYTEKNATGNVL
                     LLFLLLILAHRNTLTSITALLFLFCCALYAPVGMTYGKINNSFIVALLQTTADEAAEF
                     TGMIPVYHFLVSAAILVFMVIFWRTHHRGQRNAMALLLFVLCSVNSWPLRMVKGTVVG
                     TTDTLREMQRYEQLSRHGADSWKILPGAPLYDTIVIVTGESVRRDYMSVYGYPEPTTP
                     WLNTAPGLFIDGYTSAAASTVPSLSRTLIYDYEQNPDSGNNVVALAAKAGYSTWWISN
                     QGKLGEHDTRISVIASDADHTVFLKKGSFASRKTDDMLLLQETERALADTSTPKVIFL
                     HMMGSHPNPCDRLHSWQNNYLEQYSRKIACYLASISKLDNFLGQLDGILRRHSRHFAM
                     LYFSDHGLSVSDSANPVHHDGHVQGGYSVPLIITASDITSHQSVSRKISARNFAGIFQ
                     WLTGIRTENIPPFNPLTDEDNEPVMVFNGERYVQEDSLKPQPLILPDHR"
     gene            complement(67236..67976)
                     /locus_tag="IRB70_001120"
     CDS             complement(67236..67976)
                     /locus_tag="IRB70_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin family protein"
                     /protein_id="HBC0631065.1"
                     /translation="MNKVIAVSALAMAGMFSTQALADESKTGFYVTGKAGASVMSLAD
                     QRFLSGDGEETSKYKGGDGHDTVFSGGIAAGYDFYPQFSIPVRTELEFYARGKADSKY
                     NVDKDSWSGGYWRDDLKNEVSVNTLMLNAYYDFRNDSAFTPWVSAGIGYARIHQKTTG
                     ISTWDYGYGSSGRESLSRSGSADNFAWSFGAGVRYDVTPDIALDLSYRYLDAGDSSVS
                     YKDEWGDKYKSEVDVKSHDIMLGVTYNF"
     gene            68215..68356
                     /locus_tag="IRB70_001121"
                     /pseudo
     CDS             68215..68356
                     /locus_tag="IRB70_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012602590.1"
                     /note="internal stop; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase"
BASE COUNT        16822 a        18255 c        16848 g        16431 t
ORIGIN      
        1 aaaattaaac aggcaaaaat acaatgacat taccaacgac tatttattca tttcctgcat
       61 attcaccccg tttttcgtcc accgacaaac cagtaaaatt aaaatttcat caatacgcac
      121 gcgctacatt actttcaaat cgtggaagag accataattg cgatggcaga catactgttg
      181 agatccacaa actagatctc tcagactggc aagcattcaa taagctagcg acgaggtgta
      241 atgcttacga tggaataaca atgaatggtg ataattcttt tggatggagc catgaagcta
      301 cattagataa tattcacgcc cagaaataca ataaagctta cgcgggtgcg cggttaaccg
      361 cagaactgaa atatttattg caagatgtcg aatccttcaa acccaacagt aaatacacaa
      421 tacacgaagt ggttttggga cctggttatg gtactccaga ctataccggc caaacgatag
      481 gatacgttgt aacccttcct gcccaaatgc ctaattgctg gtcatctgaa ctaccaacaa
      541 tcgatcttta tatcgaccaa cttcgcactg ttacaggcgt ttctaatgcc ctcggattca
      601 tcattgctgc attgctaaac gcgtattctg atttacccca tgatttgaaa attggtctgc
      661 gttccttatc aagttcagcc gcaatctact cgggtttggg tttcgagcga gtgccgcagg
      721 accgagacat cagttgcgct cgtatgcatc taacgccagc aaaccatcct gaattatgga
      781 cacaagagaa tggtgaatgg atctacttgc gaaactaata cctgacgaaa aatagaaagc
      841 aaaacgccga ccactggtcg gcgtttttac gtctcgttga ataacgaatt attcagctac
      901 tacgtttacg atcactttcg cgaatacttc gctgtgaacc tggaagctca cttcgtgttc
      961 gccagtggta cgcagaacgc cgttcggcag acgaacttcg ctcttagcca cttcaacgcc
     1021 agctgcagtt acagcgtcag cgatgtcgcg agtaccgatg gaaccgaaca gtttaccttc
     1081 gtcgccagct ttagacgcga tggtaacagt ttccagtgca ttgattttct cagcgcgagc
     1141 attagctgct gccagaactt cagccagttt agcttccagt tcagcgcgac gtgcttcgaa
     1201 gaattcaatg tttttcttgg tagctggaac agctttaccc tgcggtacca ggaagttacg
     1261 agcatagccc gctttaacgt ttacctgatc acccaggcta cccaggtttg ctactttatc
     1321 aagcagaata acttgcatta ccttatcctc tcaaagtcgt attaatggac cgtgaccgat
     1381 tactgatggc gatcagtgta cggcagcagg gacaggtagc gagcgcgttt gatagcgcga
     1441 gccagctgac gctggtattt tgcacgggta ccggtgatac ggcttgggac aatcttaccg
     1501 ctttcggtga tgtagttttt cagcgtagcg atatctttat agtcgatctc ttgaacgcct
     1561 tccgcggtga aacggcagaa cttgcgacga cggaaataac gtgccatatg gctagtctcc
     1621 agaatctatc aattcaatct gctcggcatg caaaaccatt ttgctcagtc cgttctttgc
     1681 cttgtggcat gaaatgaacc cctgaacggt tatgcgactg ccgaccgtta tactgtgagt
     1741 aatggcctgg ttttcgtgtc cgctaacaat aacgggcatt tggcaccacg cctgccggtg
     1801 aaaaccggct tcctcctgca cagaacgatg ctcaagcacg aactggcagt gaggaattcc
     1861 tgatggactg acctttcgaa ggggagtcct gcacacggtg ccggacaaca ccagacggtt
     1921 ggtcatcaga aattactctt cagaatcccc agcttcagca tcatcagcgg tttcgtttgc
     1981 gaaatcatcg cgacgctcac ggcgctcgtc tttcgcttta accatcggag atgcttcggt
     2041 aacagcgtgc ttggtacgca taaccatgct gcggataacg gcatcgttga agcggaaggt
     2101 agtttccagc tcatcgatca cttcctgcgg agcttcaacg ttcatcagaa cgtagtgtgc
     2161 tttgtgcagt ttgttgatcg ggtaagccag ctgacggcgg ccccagtctt ccagacggtg
     2221 gatcttgcct tctgcaccag tgatggcagc agtgtagcgc tcgatcatgc ccggaacctg
     2281 ttcgctctgg tcaggatgga ccataaaaac gatttcgtaa tgacgcatcg aattgctcct
     2341 tacggattat tcagcctcct gtctgggtca gccgaatccc ggggaggcaa ggaacgtgtt
     2401 aaaggtcggc tgaaaaatga cgcgttatag tacttgtatg ccccgctaaa ctcaaggcca
     2461 gccgacaaat aaatctcatc cttcaccaag tcgtactaac acgctgattt gaagttcatc
     2521 acacttcatc atggtgtttt tttgaacaac tgcatcagaa atggtcacca tccacttctt
     2581 tatcattgat taaaattaaa tcagaagatc accacaagag gagagcacac aaagtcagcc
     2641 atcgaggagg tatctatgtt cagtcgcgtt ttagcccttc tggctgtgct tttgctaagt
     2701 gcaaatacat gggcagccat tgaaattaat aaccaccagg ccagaaatat ggacgatgtg
     2761 caaagcttag gcgtgattta tatcaatcat aacttcgcca ctgagagtga agcacgtcag
     2821 gcattaaatg aagagacaga tgcgcaaggc gcaacgtact accatgtgat tctgatgcgg
     2881 gaaccgggga gtaacggcaa tatgcacgcc agcgcggata tttatcgcta gcaccaggta
     2941 taaccaacga aacattgcca tagtttgctt tgcccccttc gcagggggct ttttttgaaa
     3001 aacggctgcg gaattagacc agttatctcc cgaagaagga aatttccgca gcgcgtgttc
     3061 tacttctgcc cgtaataagc gttaggaccg tgtttacgca tgaagtgttt attcatcagg
     3121 aagctgtcga tgtgattgag ttgtgggtta atactgcgcg caatccacgc cattttcgcc
     3181 acttcttcca tcaccaccgc gttatgcacc gcatcgtgag catctttccc ccaggcgaac
     3241 ggcccgtgct ggtacaccac aatccccggt gtatgcagcg gctcggcgtt gcccagcgtt
     3301 tcgataatca ctttgccggt gttcagttcg tactcaccct gcacctcttc ttcgcttaat
     3361 ccgcgcgtac acgggatatc accaaagaag tagtcggcgt gcgtggtgcc taacgccggg
     3421 atcgccagcc ccgcctgcgc ccatgcggta gcatgagtgg agtgggtatg gacaatacca
     3481 ccaagcgacg gataacgacg gtagagttcg agatgcgtgg cggtgtcgga agacgggcga
     3541 tattcccctt ccaccacctt gccgctcata tcaaccacca ccatatcggc cgctttcatg
     3601 gtttcgtagg caacgccgct gggcttgatc accaccagcc cgcgttcgcg gtcgatagcg
     3661 ctgacgttgc cccaggtaaa ggtcaccagc ccgtagcgcg gcagctccat gttggcttca
     3721 aatacctgct gttttagctt ttgcattatg ccgcctccac catgcccgct ttcgccatgc
     3781 gcgctttcac ccaatcacgc gctttcgcca cttccgccgc cgggtcttcc gccgtttcgc
     3841 tccacatctc aatcaggtac ggcccgcaat agccactctg tttgagcgtt tcgaagcaac
     3901 gttcaaaatc cactacgcct tcgccaaacg gcacattttt gaagacgcct ggtttggtgt
     3961 ctttcacatg caccgcgacg atatgcccaa ttccggcctg caattccatc tgcacgtcgt
     4021 tgtcccacgc cgacaggttg ccgatatccg gatagagctg gaaccacggg ttgttgagat
     4081 agtgcgcata gcccagcgcc ttgctgatgg agttcatcaa tggataatcc atgatctcca
     4141 ttgccagcgt cacctgcgcg cggcttgcca tctcaacgct ctctttcagg ccgtcacgga
     4201 aacgacgacg cgtttcgtta ttggcttcct gatagtaaac gtcatagccc gccagttgga
     4261 ttacgcgaat gccaacgtcc tgggcgaact ggatagcttt acgcataatc tccagcccct
     4321 gcgcccgtac cgcgtcatct tcgctaccca gcgggaaacg acgatgagca gaaaggcaca
     4381 tagacggtac gcgcacgccg gtttcaacaa tcgcattcac cagtgccaga cgctgctcgc
     4441 ggctccagtc gaggcgcgac aggcgatcgt ccgtttcatc taccgacatc tcgacaaaat
     4501 cgaagcctaa cgtttttgcc agttgcagtc gttccagcca gcactcccca gcggggagtg
     4561 ctttttcgta gatgccaagc gggatttgtt tggacaacat atccgctcct tagccccaca
     4621 gttcggcgat ggaacgtttg aactgacgcg cggcttcaac cggagaagcg gcatcacgga
     4681 tgctgcgacc agcgataaac acgtgaatcg gaatgccttt gaacagcggc agatcttcca
     4741 gcgccaggcc accggtgacg gtcactttga agcccatatc ggaaagacgt ttgatcgcgg
     4801 taatgtccgc ttcgccccac gccacgcctg cggcctgtgc gtcacggctg cggtgataaa
     4861 ccacctgctg aatgcctgca tcgcgccact gttgcgcctg ttcccaggtc cagtaaccgg
     4921 tcagttcgat ctgcacgtcg ccgttaaact cttttgccac gtccagcgca cctttggcgg
     4981 tgttgatatc cgcacagcaa atcacggtca cccagtcagc gttggcttca aagcacatac
     5041 gagaaaggat tttgcccgca tcggcaattt tggcgtctgc cagtacgatt ttgtgcgggt
     5101 aaagcgcttt cagatcgcga accgcacgca cgccttcgcc cacgcacaga atggtgccca
     5161 cttcgataat gtcgacttct tcggcaatca ggcgagtggt ttcgtaggcg ctatccatag
     5221 tctggttgtc cagcgcgact tgcaacatcg gtaatgacat gttcaattcc ttcttaagct
     5281 gccgcgttgg tgcggtcaat taaatccagt acttcctgct cggtacggca ggcacgtaaa
     5341 cggtcgaaat tctcttcatc ttcaaacagg ttgacgatct gcatgatgcc cacttcctgg
     5401 tgagtgttgg catcaaccgc cgccatggtg atgaggatat ccaccggatc gttatcttcg
     5461 tggttgaact ccagcggctt tttcagcgtc accagcgcaa aaccagtttt cttaaccccc
     5521 tcttccgggc gtccgtgcgg cattgccagg ccgggtgcga gcacaaagta cgggccgtgc
     5581 tgttcaaccg catccagaat cgcctggtag taacgcggct ctaccacatc tgccgctacc
     5641 agcagatcaa cgccgatttt cactgcgtcc tgccatgtct ctgcttccgc ttgcaggcgg
     5701 atagatttat tttcagccag cgaatcacgt aatttcatgg cgcgtcctta cttcacgtcc
     5761 tgcgggaaat gctctttgat cacttccagc agtttcgggc caaaatcagc aggagagagc
     5821 atgttgcgca cgccaaccac atatttgttg ccggtcacgg tgatttcgcc cgcaatatgg
     5881 gtagaagcga tgatgatatc cgcaccgctc aactcgcttt tgtattcgcc aaccgcgcag
     5941 ctgtttaccg tgtggtcaat gtttgattgg gttaaaaact ggtccacttt catcttcatg
     6001 atcatggaac tgccttgtcc gttgccacac acagccagaa tacgtacggt cataatcaaa
     6061 actccttatt aagcagactg ttctgccagt tgtttttctg catcttcttc tgcgcgcagt
     6121 gcgcggccag cgaagaacat ataagccagt gcaattacaa tgatgacagc cataaaggcg
     6181 ataccgatgg agaagaagcc ctgcatcatc ggcggtgcca gaatcgacca gtccgccata
     6241 cccatccagg cactcatacc ggtaagtttc accgcccaga cgcaaccaaa gatttcgatc
     6301 atccccatca ccagacaaat cttcagcgcc gcacgccagc cgccgaagtg gttagcgaac
     6361 acgccgatgg tggcgttgga gaagaacatc gggataaagc cggggataat caggatcgag
     6421 gaaccgcagg cgaccaggat gccaaccgca atcagctgac cgatggtgcc ccacataaag
     6481 ccccagacca cggcgttcgg cgcgaagcta taaatagccg cacagtcaat cgccagaacc
     6541 gcgccaggga tcaggcgctg agagataccg ttaaacgctt cagagagttc cgctacaaac
     6601 atgcgcacac cctgagtgat gatgaagatc gccaccgcga aggagaaacc ggtttgcagg
     6661 atatacaccg tccagttcac tttgcctgcc atcgcctgca cggtgtcgat accgaaggag
     6721 agcagaatgg caccaaagaa gatggtcatg acaatcgccg tggagacgat gttgtcgtgg
     6781 aaaatattca gccagcctgg cagtttgagg tcttcaacgc tttcctcttt tttgccaagg
     6841 aacggcgcaa ccttataggc aatccatgat gcaaactgtt gctggtgacc gatggagaaa
     6901 ccgcagccgt ccgtcacttc ctgagtcggc ttgtacatca tgttggaggt tatgccccag
     6961 tagagcgaaa ccagaatcgc cgtgcagata atggtcgtcc acatggaata gccgaaaata
     7021 aacaacgtaa cggcaatcag tcccgcctgc tggaacatga tgtgtccagt cagcatgatg
     7081 gtacgaatac cggtaatgcg acgcagcagc acgtaacaga tgttcagcgc cagcgctaac
     7141 aacaccgcgt aacctaccca gctataggca tcgcccatgc ggtcgatggt tgccatcatc
     7201 gacgcgtaag tatcggaaat tgcgccgtta atgccgtaga cttcggacat tttcgccacc
     7261 accggtttga aggtgctggt gaggatgccg gaccctgcct gcaacaacat gaaaccaatt
     7321 atggttttaa tcgtgccttt aataataacg ctgacacttt tgcgcagtag gatgtagccc
     7381 agacaggtca caatacccag caacaacggg gcattggtca tgacctggtt aaaaaacacg
     7441 gtaaagatgt tgtagaggat ctccataacg atctcctgaa gaagaggtaa ccgggtattc
     7501 cacacacccg gaatgttgtg cattcactct aattttcaaa agtaatcaca acaagattat
     7561 ttatgattaa atgtgacgcg acccgcaaat aattccacat ggatagagtg ggattcacac
     7621 aacgaaataa ttattcattt aaattcattt agttaattga attacacatt ccattaaatc
     7681 tttccacact caaaatcaac aacaacttcc ctggcaaaaa gtcaaaaaat ggtcattgcc
     7741 ttcctgaaaa aatagtgcca ggattaatca aaaccaatca catgttgatt cgaattgaac
     7801 tatcatgaag gtaaatggcg atgagtaaag tgaaaagtat cacccgagaa tcctggatcc
     7861 tgagcacttt cccggagtgg ggtagctggc tgaatgaaga aattgaacaa gagcaggtcg
     7921 cccctggcac atttgcgatg tggtggctag gctgcaccgg gatctggctg aaatcagaag
     7981 gtggcaccaa cgtttgcgtt gatttctggt gcggcactgg caaacaaagt cacggtaacc
     8041 cgttaatgaa acagggtcac cagatgcagc gcatggctgg cgtgaaaaaa ctgcagccaa
     8101 acctgcgcac caccccgttt gttcttgatc cgtttgcgat tcgccagatc gacgcggtac
     8161 tggcgactca cgatcacaac gatcatatcg acgttaacgt cgctgctgcc gtgatgcaga
     8221 actgtgctga tgacgtaccg ttcattggac cgaaaacctg cgttgatttg tggattggct
     8281 ggggcgtacc gaaagagcgt tgcatcgtcg ttaaaccggg cgacgtagtg aaggtaaaag
     8341 acattgaaat tcatgcactt gatgctttcg accgcacggc actgatcacc ctgcctgccg
     8401 atcaaaaagc agctggcgta ctgccggacg gcatggacga tcgcgcggta aactacctgt
     8461 tcaaaacccc aggcggtacc ctgtatcaca gcggcgattc ccactactct aactattatg
     8521 cgaagcacgg taacgaacat cagatcgatg tggcgttagg ttcatacggc gaaaacccac
     8581 gcggtattac cgacaaaatg accagtgctg atatcttgcg tatgggcgaa gcgctgaatg
     8641 cgaaagtggt tatcccgttc caccacgaca tctggtcaaa cttccaggcc gatccgcaag
     8701 aaatccgcgt gctgtgggag atgaaaaaag atcgtctgaa gtatggcttc aagccgttta
     8761 tctggcaggt gggcggcaaa tttacctggc cgctggataa agacaacttc gagtaccact
     8821 atccgcgtgg tttcgatgat tgcttcacta ttgaaccgga tctgccgttc aagtcgttcc
     8881 tgtaatctgt cgtttatacc ggatagcgtg gagtagttcg cgctatccgg cgtagtattt
     8941 cctggctatt tcaaatatca tctaaaaaaa tcaaatttta tcggaatagc tcatgactga
     9001 agcacaaaga catcaaatcc tcctggaaat gctcgcacaa ttgggctttg tgaccgttga
     9061 gaaagtcgtt gagcgtctgg gaatttcgcc tgccactgca cgacgcgata tcaataaact
     9121 tgacgaaagc ggcaaactga aaaaagtgcg caatggcgca gaagctatta cccagcagcg
     9181 cccacgctgg acgccgatga atctgcatca ggcgcagaat cacgatgaaa aagtacgtat
     9241 tgctaaagcg gcctcgcagc tggttaatac gggcgaaagc gtagtcatca actgcggctc
     9301 caccgcgttt ctgcttgggc gggaaatgtg tggcaagcca gtgcaaatca tcactaatta
     9361 tctaccgctg gcaaattacc tgatcgatca ggagcatgac agcgtgatca ttatgggcgg
     9421 acagtacaac aaaagtcagt ccatcacttt aagcccgcag ggcagcgaaa acagtctcta
     9481 tgccgggcac tggatgttta ccagcggcaa agggctgaca gcagaagggt tgtataaaac
     9541 cgatatgttg acggcaatgg cagagcagaa gatgctgagc gtggtaggga aactggtggt
     9601 actggttgat agcagtaaga ttggcgaacg cgcgggaatg ctttttagcc gtgccgatca
     9661 aatcgatatg ctgatcaccg gcaaaaatgc taacccggaa atcctgcaac aactggaagc
     9721 gcaaggggtc agcattctgc gtgtttaaag atgctggcgg aaaaatgtca cggcagcatc
     9781 taacgcctca ggcgtaatgc ggtgacgcac gccaggctgc catgaacagg ttagcagttt
     9841 atcccgtccc gtctcgctta aggcctgctg caaacgtagt gattcgtcgg caggcacgac
     9901 gtcatcgtca aggccatgcc acagcagtag aggtctgtca ccaagttgtt ccaggtggtt
     9961 tgtcgcttcc cactctgcca gcggcgcgac aatgttattg aattcattct gctgtgctgc
    10021 cgtttcaggt atcagcggtg gaaacagtga acgggcgagc aatgtaaaat agcccgatcc
    10081 catcatgctg gcggtacatt tcaccgtggg gtggcgagcg gtaattccca gtgccgtcat
    10141 cgcgcccatc gacgcgccac cgactgccag acggtcatca agcagccagt tttcttcggc
    10201 tattgccgca cgtaaagtag tgaattcctg catactttgt agcaagattt gccagaattg
    10261 atttaaccgc cgcgctgcgt cgccactaaa acgactaccg tgatcgggcg catccggcat
    10321 gatcacccgc aaaccagcct gcgccagcgc aacggcaaaa tagctataca ccagactgga
    10381 cgaagtaaag ccgtgataaa aaatcgcgca cggtaacggg gtatcttttt gcccgacagg
    10441 ataagcatga agaacgggaa tatctgccag ctcgcgtgat tctatttcaa tcatctgtct
    10501 ctcctttttg tctggtatga catgaagaaa tccttagcac aagtttctgc tggcggtatt
    10561 agttcataat gttgagatgt gggttacgct ttcatcacgt tttcattcga aaatcgcgta
    10621 ccaggtaaca attcgggaac attcccccaa agttaaatta ataaggcact acactatggt
    10681 tagcaggaaa cgtaatagcg ttatttaccg gtttgccagt ttattattgg tgttgatgtt
    10741 aagtgcctgt agcgcactgc aaggtacgcc acagccagca ccgccagtaa ccgaccatcc
    10801 gcaagagatt cgccgcgacc agacgcaagg gttacagcga ataggtagcg taagcacgat
    10861 ggttcggggt tctccggatg acgcattagc agaaatcaga gcgaaagctg tcgctgcaaa
    10921 agctgattat tacgttgtcg tcatggtgga cgaaaccatc gtgacaggac agtggtattc
    10981 acaagccatt ttgtaccgta aataaatcag acaacttaca tagtcagctt tacattgctt
    11041 tgcgtcccta tgcgtttacc tgtgcacaat aaattaccgg ctggaagcct gggcgtttat
    11101 taccgcgatg gaatgccctg caacatgtgg ggaaacgaaa aatggagctg acgatgaaac
    11161 aattacttgc ctcaccctcg ctgcaattag tgacttatcc tgcgagcgcc acggcacagt
    11221 ctgcagaatt cgccagtgct gactgcgtga cgggcctgaa tgaaataggt cagatctcag
    11281 ttagcaatat ttcaggggat ccgcaggacg tggaacgtat cgtggcgtta aaggccgatg
    11341 aacaaggtgc gtcatggtac cgcattatta ccatgtacga agaccagcag cctgataact
    11401 ggcgcgtaca ggcgatcctg tatgcgtgag tatcatctac agcaaatgaa caatgccgga
    11461 tgcggcgcga gcgccttgtc cggcctacaa ttttaaaata tttcatttag ttaatcgaaa
    11521 ccagcgtcgc atccgtcgta tacgcttaca aacacactcc tcccgtcgcc cgcagcaata
    11581 aatcattctg gatctgctct gacaaccgta cgccgccgcg cgtatctaac atcacctgac
    11641 accacgcctg cgccattggc ggagaggcat atttcaacat ttgcgcaccg cagcccagca
    11701 ggaatagctg atgagtaatc tctcgcccca attcttcagc tggcttacgc agctgctgct
    11761 gtaaacgacg aaccgcgcga tcaaaatagc gatcctgccc tttcacttcc acaaatgctt
    11821 ccgacaataa gtcgtatacg cccgcttgct tattgagaac gcgcagcaca tccaggcaca
    11881 taatattgcc ggaaccttcc caaatactgt ttaccggcat ctcccggtaa agccgcggca
    11941 gctcgctctc ctcgcaataa ccaatgccgc ccagcacctc catcgcttcg gccacaaacg
    12001 gaataccatg tttgcagatc acaaatttcg ccgcaggcgt aaataaacgc gcccacagag
    12061 cttctttggc atcggcacgc cggtcccacg ctcgcgcaag acgaaacagc aacgccgttt
    12121 gcccttcaag ctgaagcgcc atgcgactta agacatgacg cataaggggc tgttggatca
    12181 atggattacc aaaaacatgg cgttgatgtg catgataaat cgccagcgaa aatgcacggc
    12241 gcatcatggc atggctaccc agggcgcaat caaaacgcgt catcccaccc attttcagga
    12301 tcagacgaat tccttcccct tcctgcccca acaaccagcc aatggcatcc tgaaactcca
    12361 cttcgcagct ggcgttagag cgattaccca gcttatcttt cagccgctcg aggcgaatcg
    12421 cgttgcgttg cccgtcaggc aaaaagcgcg gcacaaaaaa gcaggacaaa ccgcccgtag
    12481 tctgcgccag caccagatgc gcatcgcttt gcggcaccga gaaaaaccat ttatgcccca
    12541 ccagccgata agagccatct tccaggcgct ctgcgcgggt ggtgttgctc atgacatcgg
    12601 aaccgccctg cttttccgtc attcccatgc caatcaacaa accgcgtttt tgcccacctg
    12661 gcaataagtg agaatcgtag cgatcgctca acagcggcgt ggtccagtcc tgaaacggcg
    12721 cgggtaacat ctgtaacagc aatggcgtgg cggcaaaggt catcgttatc ggacataacg
    12781 acccagcctc aacctgcgca tgtaacataa aacgcgccgc gcgcgccaca aatgcgccgg
    12841 agcgagcgtc ttcttcccag gcaagattgt gcacccgatt ggtacatagc gcctgcatca
    12901 gcaggtgcca ggcggggtga aaacgcacat cgtccagacg gcgtccttgc gcatcgtagc
    12961 gcaataattc aggcggattc acattcgcca gccgccccag ttcaagggat tcagccgtcc
    13021 ctaactgctg accaatactg gctagaaaat cgctatccca gccagcacct tcacgcgtta
    13081 ccgcttcgca gagcgcgcca tcagacaggt ataaattgct gttatttaat ggtataggtt
    13141 gattaaaaac ggtgtgagtt tgccagtgca ctgtgtctcc ctccatcaat ggcagtcacc
    13201 attagtatgg tcactgccat ggattcatga cagaaagaga ttgctaaaac attcttatcc
    13261 agcaatgtaa tgcggaacga aacgtgaggt gtctttggtg atcaacgtgt tatcttcacg
    13321 gatccccatt ccgcacgctt catcatcgac aatccagcta ccgatgagtg tgtagctatc
    13381 gccaaatcgc ggcagaggtt gaaacgcctg gtagatcatc ggttcatcgg cgtaatcacc
    13441 atcagcgtgg tcaacgacgt tattctgacc gtcgaaaatg gtgacgtttc cgccttcgcg
    13501 cgagtaaatc ggtttacgca catagctttc gccagcggca atctgcggtt tttcaccctc
    13561 aaaccaggat gcaagaaggt taggatgacc agggaagaag cgccaaagca gcggcattag
    13621 ccctttatta ctcaagatac ttttccataa cggctccacc cattgctcac gacgcttgcg
    13681 cagcagcgga ccgttatcgt cacgcatcat ccactccagc ggatacagct taaatgcacg
    13741 ctggatgaca ttatcatcaa gatcggtcag tactccgccg acgcccaaac cgagatcttc
    13801 aatgtagata aaccgcgact cctgccctgc ctgctgggcg cagtcctgca agtacagcac
    13861 ggtactcctg tcttcatcgg tgtcctgaca gcagcaaaaa taaaacggtt cccgactgta
    13921 aagctcacta aagcgcgaaa tcaggcgttc ctgaatggca ttgtactgat cggcatcacg
    13981 cggaataacg ccgctgcgcc gggcatcttc cagccacaac cactggaaat aagccgactc
    14041 gtacaatgaa gttggcgtat cggcgttgta ctccagcaac ttaaccggtg cattaccaca
    14101 ccaggcaaaa tccatacggc catacaacga aggatcgcgt gcgtgccagc tttcggcgat
    14161 cacatcccag tacaacggcg ggatcgccag ttgcgtcagg atctcttcat ctttaaccgc
    14221 acgatccacc acctccaggc acatctgatg cagttccgca gtcggttttt cgatctgctc
    14281 ttcaatctgg cgcaaagtaa agcgataagc ccgactctca tcccaataga tttcattgtc
    14341 gatgatatga aagtcaaatc cgttatcggc ggcaatccgg tccagatccc gccgcacagg
    14401 aacgttgtgt ctcagcatga ttagcctccc caatgcccac gggcgctgga agaacgacca
    14461 tagccgccgc gagaaacggt tgacgctttt ttggtggtaa agccgcccga agagtaagac
    14521 tcttttttgc cagaaccgga gcgccaggag taatcaccga aagtgttgcg ccagacgggg
    14581 cgggaagcaa atgaggatcc gccgctgtta tagacgaacg gctcatcgcg atctttacga
    14641 ataacccggc ttaacaaaaa tccagaaacg accgggatcc aactctgttc aacattgtcg
    14701 tagtaacaat tttcatactt agactgacaa ttctgctgag tcatattctt cggaacatcg
    14761 gcataaaacg ccgctttggc gttgttccag ccatgagcac agatatctga attattaccg
    14821 tcatcaatac aatcctgcac agtcgagtaa aacgttccgt cgccgtcgtt atcgacatcg
    14881 ccactatcgc cacaaccttt caatacgaaa aaagcggcac cgcccattag cgccaacgtt
    14941 aagtattttt gtgcgtagcg attgcgacgc ggttcaaaag gattattcgg tctgccaatg
    15001 cgactgatcg ctccgtgacc aattttactg ttatttcttg atttgcgttt tctggccatg
    15061 atcgtccatt accatgtcat acaagctgcg ttaaaaatac caccagccag tgcggcggtt
    15121 cccataaaca ttcctgctgc ggtattgtga ttaataattt tttcgcttaa tgcgggcata
    15181 taaagtctga cgccagcaaa aacgagtaac tgaatcacca gtgcaatccc gccccaggcg
    15241 aaataatccg gaatactcac cgcattgatt gccgcactgg ataaggggat cacgtaaccc
    15301 aacaatgtac cgctgaatgc cagtgacgcc gcggtattat tgtttttgat taattgccat
    15361 tcgttgtgcg gtgtaatttt ggagtagata aacagaaaaa taatcaccat agccacgcca
    15421 ataaaaaaat aggcgctaaa ggcaagaagt gaatccagta tatgcatcgt aaacgtcctt
    15481 gtaattaacc aataatatga agtgatgtca gtgggatatc aacacccagc gcgcgcgaaa
    15541 ataaccactc cggctcgccg agatcgttaa aagattcctc accatttaac agtaaatatt
    15601 cacaggtatc ttcggtcacc tgccgttcat agcccatggt aaaattatgc acttcccatt
    15661 tggcgtggtt ttgattttca actttttcca gcatatagac gggttcgata ttccccggtt
    15721 cttcgctgtt aaaaaatcgc tgccagcgtt tttcctgcca gtttaaggtt atagccccca
    15781 tcgctttggc gttgatcgcc tcgcgccagt gactctcttt actgataccg tagctctctt
    15841 catagacaaa gagcttgata tcatcaatgt catcaatatt ttcgccgccg gtggtattga
    15901 tttgcagaaa ctcatcgcct gaagtgtagt agcggaaaat ctggctaccg ccgcccagat
    15961 cgatgcggct gacggcggct accgtaaatt cctcacccgg cagcgcaatc agcaattcat
    16021 cttccagcaa acgaaacgct aacgtgtcga gcgtaaagcc actattgaga tgaagtccca
    16081 gcggaccacg agcgatagca ggcttattat ccttgccaaa cagacgctgg aaaaaaccag
    16141 acatatttta tccttataat agttgccagc cttgcagtga ggctggcaaa aaattactcg
    16201 ccctgttggc gttgcagtct tgctaataca tcctgggcga tacttttatt gctaccgcca
    16261 attccggctt ccgccagctt ttcatcgaga tcgcgaccgt ctgcgacttt ttccaactgt
    16321 gcggcagcat ccaggcgagc ctgacgttcg gcctgacgcg tttgcaggcg ttttaaggat
    16381 tctgccgctg tcgaaacgct ggaagatgcg ccaacggtag aggtcgttac agcctgttgt
    16441 gcacgctgca tggcttcagt ggctttaacg acttccattt gctgctcaaa ctgagcgata
    16501 cgctgcgctg tcgctgtaac tgctttttcc acgccatcac gagagacttc cagattcgac
    16561 aacacttgct cttcagcggt aatgagattc tcaaggcgcg cgatttcttc agcaacttcg
    16621 ttaatcaacg acggattcac gttcttgctt aacgcttcca gcgcacgagc ttccagactg
    16681 gctttgcgct cacgtaaatc tttcagctta tcgtgactta atttcactcg cgccagcaga
    16741 tcaacgcgag attttccggc tttatcgagt tcagctttag cgtcacgaat atgctgttcc
    16801 agcatgcgca cgccctgggt ttcttcaatg gactcttccg cctgggagat aaacgatttc
    16861 cccagcgtaa ataaactttt taaaatcccc ataaataccc gtccttgtaa ttagtgtgaa
    16921 tattcttctg taatttcagc cagatccaat gcgttatcta ccagcgaggt tatctcaagc
    16981 agaatatctt caagagaaga tttaagcgat aacgcaccga aaacaatgta atactcttcc
    17041 tgttgcacgc tggagatccc taccgatgac aacggcatca tcttctgatt tcttaataag
    17101 aaggtattaa attcatctgg attgctgata ctacttaccg gacaaataaa ggtttcgatg
    17161 atcatttggc gggaagtaaa aagaatattg atttgcaaat cgccataatc attcatttta
    17221 ataattaatg cgctttcgct atttgttaca tcaatatttt gttcaggtac agtttgcagc
    17281 gccgtcgcca gcgccaacgg attccatgtc atatattatt ccatatagat taagtttaaa
    17341 tattaataaa atgaatattt acagtacgta attatcttac cagctataga caaaaaaaaa
    17401 ccatccaaat ctggatggct tttcataatt cagaggaact agctgcgctg acgaaccgct
    17461 tcaaataagc aaattccggt tgcaaccgaa acgttcaggg aagaaacact tcctgccatt
    17521 gggatgctga tcaactcatc gcaatgttca cgggtcaggc gacgcatacc ttcaccttcc
    17581 gcgcccatca ccagcgccag gcgtccggtc attttgctct gatagagtgt atgatccgcc
    17641 tcgcctgccg taccgacgat ccagatattc tcttcctgca acatacgcat ggtgcgcgcc
    17701 agattagtca cccgaatcag cggaacgctt tctgccgcac cacaggccac ttttttcgcc
    17761 gtggcgttga gctgtgcgga gcgatctttc ggcacaatca ccgcatgaac accagcggcg
    17821 tccgcgctac gcaggcacgc gccgaggttg tgcggatcgg ttacgccgtc gaggatcagc
    17881 aggaacggtt gatcgagcga agcgatcaga tccggcagat cgttttcctg atactgccgt
    17941 cctggcttca cacgagcgat aatgccctga tgcacggcac cgtcgctttt ctcgtcgaga
    18001 tattggcggt ttgccagctg gataaccacg ccctgggact caagggcgtg aatcagcggc
    18061 aacagacgtt tatcttcacg gccttttaaa ataaagactt cctgaaaacg ttcaggggcg
    18121 cgctccagca gggcctgcac tgcgtggatg ccgtaaatca tttcgctcat taatgtactc
    18181 gttgtttacg ttttgcctga tgcgctacgc ttatcaggcc tacatgatcc ctgcaatgta
    18241 ttgaatttgc gtgattatgt aggccggata aggcgttcac gccgcatccg gcatgaacaa
    18301 agcgcatttt gtcagcaatc taaccctctt ctgtttgaag agggtaatga tcactctgcc
    18361 acttttttct tcgccgcacg cttcgctttg gtcgctgcgg ctattttctg cgttttcgcc
    18421 gatggctttt tcgcttttct cgcgtctttc ttcgccgctt tcggcttcgt ttttttctcg
    18481 ccgcggaaag cgctgtctgg ctcaaagttt acctttttac cgacctgacg acgcttgccg
    18541 ccttttttac ctgcatcgcc ttttttcgct ttctcgcgcg ccgttttacc gacgttgcgc
    18601 ggtgcgcgtt cgctggagat caggctaaag tcgattttac gctcgtccat attaaccgct
    18661 tcgacgcgaa cttccacgcg atcgcccagg cgataagtct ggccgctgga ttcacccatc
    18721 aggcgttgcc ctacctggtc aaagcgatag tagtcattgt ccagcgaaga gacatggacc
    18781 agaccatcaa tgaacaagtc gtccagacgg acgaagaagc caaagccagt gacgctggaa
    18841 attacgcctt taaagacgtt acctacctgg tcgagcatga agtcacactt cagccagtca
    18901 gctacatcgc gtgttgcttc gtcggcacga cgttccgcca tcgaacagtg ctgacccagt
    18961 tgcagcatct cttccatcga ataatggtag ccgccggttt cagtggtgtt gccctgatgc
    19021 ccctgctctt tcgccagcag atatttaatg gcgcggtgca gcgtcaggtc aggataacga
    19081 cgaatcggcg aagtaaagtg cgcataggac tgcaatgcca gaccgaagtg accacggttt
    19141 tccggatcgt aaatcgcctg tttcatcgag cgcagcagca tagtttgcag catttctgca
    19201 tcaggacgat cggcaaccga ttccagtaac tctgcatagt cgcgcggttc cggcttgtta
    19261 ccgcccggca attccagccc cagctccgcc agcactgaac ggaaagaggt aatcgcttcg
    19321 gtgctcggct tgtcgtgaat acggaacagt gccggttctt tggctttctc aacgaaacgc
    19381 gccgccgaga tattcgccag aatcatgcac tcttcaatta acttgtgggc gtcgttacgc
    19441 tgagtctgtt cgatacgttc aatacggcgt tcagcgttga aaatgaactt cgcttcttcg
    19501 ctctcaaatg agatcccacc gcgttcttca cgggctttat ccagcacttt atagaggtta
    19561 tgcaactctt cgagatgctt aaccagcggg gcgtactgct cgcgcagatc ctgatcgccc
    19621 tgcagaatat gccagacttt ggtgtaggtc agacgtgcgt gagagctcat taccgcttca
    19681 tagaatttgt agccagtcag gcggcctttc gacgaaaccg tcatctcgca caccatacac
    19741 aggcggtcta cctgcgggtt gagcgagcac aggccgttag agagcacttc cggcagcatc
    19801 gggataacct gcgaagggaa gtacaccgac gtaccacggt tacgcgcttc tctgtccagc
    19861 ggtgttggcg gacgcacata gtagctgacg tcggcaatcg cgacccataa acgccagccg
    19921 ccgccgcgtt ttttctcaca gtaaactgca tcgtcaaagt cacgggcgtc ttcgccatca
    19981 atggtgacca gcggtaaatc gcgcaaatcg acacggcccg cttttgcttc ttccggcact
    20041 tcttctttca gcccggcaac ttgttgctca acagcctgcg gccagatata cggaatttca
    20101 tgggtacgca gagcgatatc aaccgccatg ccggtgccca tattgtcgcc aagtacttcg
    20161 acgattttac ccaccgcttt ggtacggcga gtcgggcgtt gggtcagttc aaccaccacc
    20221 acaaagccca tccgcgcgcc catgatctga tcgggcggga ttaagatatc gaagctcaaa
    20281 cgactgtcgt caggaaccac aaagccgacg cccgcttcgg taaagtagcg accaacaatc
    20341 tggctggttt ttggcaccag tacgcggaca atacgcgctt cacgacgacc tttacggtca
    20401 gcgcccagcg gctgcgccag cacctgatcg ccatgaatgc aggttttcat ctgctcgctg
    20461 gagagataca aatcatcttt acgcccttca acccgcagaa agccgtagcc atcacggtgg
    20521 ccaataacgg tacctttcac caggtcgagg cgttccggca gcgcatagca ctgacgacga
    20581 gtgaagacca gttgaccatc gcgctccatc gcgcgcaggc ggcgacgcag gccttcaagc
    20641 tgctcttcgc cttcaatgtg cagttctacc gccagctcat cacggctggc cggtttttca
    20701 cgtttggtta aatgttcgag gataaattcc cgactaggga tgggattcgc gtatttttca
    20761 gcttcgcgtt cctggaaagg atcttgtgac atctcggttc ctccgttgtc atctctgatg
    20821 aagattttcg tcactccacc agcaataatt tataaagcgg ttgattctct tcaaccaaat
    20881 cggcaagcgt gtagttatcc agttccgtaa gaaaactttg cacggcctta gaaagtgcct
    20941 gtttcaaccg acaggcaggt gtaatgtggc aaaactcact gctgcaattc accagcgata
    21001 agggctccag ctcgcgcacc acatcaccaa tacgtatcgc actcgccggt ttacccagac
    21061 gaatgccgcc attttttcca cgaacagcag tcacgtagcc ggcacgacta agttgattga
    21121 ttattttgac catatgatta cgggagacgc cgtagacgtc agtcacttca gaaatactgg
    21181 tcatccgccc ttctggcaat gacgccatgt agatcagcgc acgtaatccg taatcagtga
    21241 aactcgttaa ctgcacatca acctcaaaag ggaaatcggg aaaaaataca tttatattga
    21301 tgataaacca gccacaagct gtgtcgctaa tttatttcag ttcggggaag gaaaaaagcg
    21361 aggatttaac actgtgtcgg atagcgtaat ggcttacccg acacagcaat gtatcacact
    21421 gttagcccgg caggcaaaat atctgccagg cgtaccagaa ttacgcgtcg aacgggtcgc
    21481 gcagaatcat ggtttcagta cgatccggac cggtagagat gatatcgatc ggcacaccgg
    21541 tcagctcttc aatacgcttg atgtagttca gcgccgcctg cggcaggccg ctacgatctt
    21601 tcacgccgaa ggtggattca gaccagcccg gcatggtttc gtaaatcggc tctacacctt
    21661 tccagtcgtc agctgccagc ggagtggtag tcacttcacg accatccggc atacggtaag
    21721 ccacgcagag tttcacctct ttcaggccat ccagaacgtc cagcttggtc aggcagaagc
    21781 cagacaggga gttcagctgt accgcacgac gaacggcaac ggtgtccagc cagccggtac
    21841 gacgacgacg acccgtagtt gcgccgaatt cgttaccctg cttgcagagg aactcgccag
    21901 tttcatcaaa cagttcagtc gggaacggac ctgcacccac acgagtggag taagctttga
    21961 ggatacccag aacgtaatca acataacgtg ggcccaggcc ggaaccggtc gccacgccac
    22021 cagcagtggt gttggaagaa gttacgtacg gataagtacc gtggtcgata tccagcagcg
    22081 taccctgcgc accttcaaac atgacgaaat cgccacgctg acgcgcctgg tcgagcagat
    22141 cagaaacgtc aacaaccata gaagtcagga tgtcggcaac agccatcgta tcatccagaa
    22201 ctttctggta atcaaccgct tcagctttgt agtagttaac caactggaag ttgtgatatt
    22261 ccatcacttc tttcagtttt tcagcgaagg tttctttgtc gaaaaggtcg ccaacacgca
    22321 gaccgcgacg tgccacttta tcttcataag caggcccgat accacgaccg gtggtgccga
    22381 tcgctttcgc gccacgcgct ttctcacgcg cgttatccag cgcaacgtga taatcaagga
    22441 tcagcggaca tgcttcagac agcagcagac gctcacgaac ggggatgcca cggtcttcca
    22501 gttctttcat ctctttcatc agcgcagccg gagacagcac aacaccgtta ccgatgatgc
    22561 tggttacatt ctcgcggaga atacctgatg gaataagatg gagaacggtt ttttcaccgt
    22621 tgattacgag agtatggcct gcgttgtgac cgccctggta gcgtacaaca tatttagccc
    22681 gttcagtcag aagatcgacg atcttacctt taccttcgtc accccattgg gtgcccagta
    22741 cgacgacgtt gttacccatt tttcaaaatc accgtttgct taaaaatgga ttctaccatc
    22801 gctttttcag agttacagca ctttttgcac tcaaaaatga cctcgatcag tctgtttttt
    22861 gttcagccaa tcgttttcct caacatgtag tagaccacaa cgcccgcaac cacaagtcca
    22921 ccgccaaaac gacgtaaaat attatcgggc aaattggtca tcgcagagat catcttcttc
    22981 catgccttcg ggtaaagcat cggccctaaa ccttccagta ccaaaaccag ggcaagcgcc
    23041 agccagattg tcgaattcat tgattatcct tatagaaaaa gaaaaccacc gacatccctg
    23101 aggatgcggt ggctttattg acctgtaccg cagtcgttat attaacgcgt tgcggaagtc
    23161 ggcgtcttca tgtagcggaa gaaatcgctg tccgggctca tgaccatcac gtcctgattg
    23221 ccagagaagc tgttctcata agcacgcagg ctacggatga atgcgtagaa gtccggatct
    23281 ttactgaatg catcagcaaa cagtttggct gcttcggcat cgccttcacc gcgcatgatg
    23341 cggccctgac gctcagcttc tgccagcgtt ctggtcactt catagtcggc agttgcacgc
    23401 agtttttccg cttcttcctg accttgtgaa cggtgacgac gcgctaccgc ttcacgctcg
    23461 gcgcgcatac ggttgtagat cgcttcagac acttcggtcg gcaggttgat ctgcttaatt
    23521 cgcacatcga caacttcaat acccagcgcc gccatactgt tcgggttgat gaccggaact
    23581 ttgcccttcg tctcagccgt tacgcgctct gccgcttcgg caatggcgtt atctgccgcc
    23641 ggggtagtaa cttcatcttc tgtacccgca gaaccggagt tcagcgcgtc acgtacttcg
    23701 agggtcagac gaccacggga atcggtgacg atgtctttca cgtccaggcg accaatttca
    23761 gaacgcagac ggtcagagaa cttacgtttc aacagcactt ccgcttgcga aatgtcgcca
    23821 ccgcccgttg ccaggtagta acggctgaaa tcgctgatgc gccatttgat gtaagagtcg
    23881 acgatcaggt ctttcttctc tttggtcaca aagcggtcgg cctggttgtc catggtctga
    23941 atacgtgcgt cgagcatttt caccgtttca atgaacggta tcttgaaatg cagacccggc
    24001 tcataaacca gaggtttgtt gtcatcgtca cgcagtacct taccaaaacg cagcgtaata
    24061 ccgcgctcac cttctttgac gacaaagaca gacatgtaaa gcactaccag cacgatgatg
    24121 ataatcgcga taactgactt acgcatcgtt attccccctg acgctggtag tcgttacgct
    24181 gcgcgttggc gcggcgttgg tccataatat cgccctgact ggtggacgac gtgttgcttg
    24241 ctccactggt tgtggaggaa gaggctggcg gcagacgcag cagattgctg gcaccgttat
    24301 cgctcttcgc cgcaggggcg ttaccacctt tcagcatctg gtctaacggc agaaccatca
    24361 ggttgccacc tttgtcgtta accagcactt tgcgggtgtt acccaacact ttttccatcg
    24421 tctcgatata cagacgctcg cgagtaattt ccggcgcagc tttatattcc ggcagaagtt
    24481 tagcaaagcg cgccacttca ccctgagctt ccaggatggt ctgggccttg tacgcacgtg
    24541 cctcttcgag gatacgttgc gcctgaccgt tcgcacgcgg ctgaacttcg ttggtatacg
    24601 cttctgcttc acgaatgtat tgctgttcgt tttcacgcgc ggcaatcgca tcgtcaaacg
    24661 ccgcttttac ttcctccggc ggacgagcag cctggaagtt gacgtccagc agagtgatgc
    24721 ccatgtcata cggacgaatc gtctcttcca gttcgcgctg ggtatcgcta cgaatcacgg
    24781 tacgaccttc cgtcagaatg cggtccatgg tgtatttacc gataaccccg cgcagggcgc
    24841 tgtcggtagc ctgacgcaga ctgtcatccg ggctggtcac gctatacaga tatttttccg
    24901 gatcggtgac gcggtactgc acgttcatct caacgcgcac tacgttctcg tccgacgtca
    24961 gcatcacacc agaagctgcc agttcacgca cggcttccac gttcaccggt ttgacttcgt
    25021 cgataaacgt cggtttccag ttcagacccg gctcaaccag atggctgaat ttaccaaagc
    25081 gtgttaccac gccgcgttcg gcttctttaa tggtatagaa accactggcc gcccagataa
    25141 tgacaatcgc tgccgctgcg atggtaacga cacgaccgcc aagctgcggg cgtgggcctt
    25201 gcgatgaact gccaccgcca gatccggtgc ctttaccgcc gcccagacca ccgagctttt
    25261 tgctcagctt gcggaagata tcatctaaat caggtggccc ttgatcgcga ccgcctttgt
    25321 ttccatttcc ctcagagttg ccgccaggtt tgctgcttcc ccacgggtcg cggtcttgtc
    25381 cgttattacc gggctgattc cacgccatgt ttgtgctcca tatttgttat gcggtgatcc
    25441 ctgttgtctt tcgacgccag aggatatgac tccacgcttc agacgctacg ccgttagatc
    25501 aggtaatcga tcaacgccgg ttcttgttta cagaggcgac gccagtcaac gatcggcata
    25561 cgaacttgca gacttacgct gccgtcctcc tccatccact ctttttctat tgcctgaagc
    25621 tgataaaaac gacttctcag acgcccttcc tgcggtggca gacgcaatgt atgctgcgcc
    25681 acctcgccgg aaagccgctc cgtcaaagcc tgaaaaagct gtggtatccc cgctccggtc
    25741 tgtgcggaaa gccagacacg gatcggtttg ttctcttcgt cccgatcaat acgcggttcg
    25801 aaatcgtcca gcatatcgat cttgttcatc accagcaggg ttgggatctc gtgagcgtcg
    25861 atctcttcaa gaaccgtatt caccgcttcg atgttttctt gtacacgcac atccgccgca
    25921 tcaatgacgt gcagcagcaa tgtggcttgc cgcgtctctt gtaacgtggc tttaaatgcc
    25981 gccaccagat catgcggcag gtggcgaata aaccctacgg tatctgccaa cacggtttca
    26041 ccgacatccg caacgtcaat acgccgcaac gtcgggtcga gggtggcaaa caactggtct
    26101 gccgcgtaga cccgcgcttc ggtgatgcga ttgaaaaggg tagatttacc ggcgttggta
    26161 tatcccacca gcgaaacagt aggaacgtcg gctttgatac gcgattgccg cccctgctca
    26221 cgctgctttt caactctttc caggcgcgac tgtatctgca cgatgcgatt acgcaacaaa
    26281 cgacggtcgg tttcgagctg ggtttcaccc ggaccacgca aaccgatccc gcctttctgt
    26341 ctttcaaggt gggtccagcc acgcaccagg cgcgtagcca gatggcgcaa ctgcgccagc
    26401 tcaacctgca acttaccctc atgggtacgc gcacgttggg cgaaaatatc taaaataagg
    26461 ccggtgcggt cgataacacg acactcgcac aaacgctcca ggttacgctc ttgcgccggg
    26521 ctcagggcat ggtcaaaaag aacgaccgaa gcacccgtcg ctttgacagc ttccgcaatt
    26581 tcaactgctt taccttcacc tacaaaatac tttgggtgcg gcgctttacg gctaccggta
    26641 atcacctgca atgcttcgac accggcggaa gagaccagag attcaaactc ctggaggtct
    26701 tccatatctt tgtcttgcgt aaaatagatg tgtaccagta ccgcctgctc accagcatca
    26761 taacggtcaa acaagcgtat aaccctctaa atagatcagc ggggaacgca ggatcgctgg
    26821 ctccccgtgt aaaaaaacag cccgaaacct tattcggttt cttcgctgtc ctgttgcgcg
    26881 gaagtattct gcgcgctgct accatgatgg tagttactgc tggtaccgcc accggcgttg
    26941 ttactgtgat gagaaaccgg gcgagacggg acaacagtag aaatcgcgtg cttgtaaacc
    27001 atctggctga ccgtgttttt caacaggatc acgaactgat caaaagactc gatttgccct
    27061 tgcagcttaa taccattcac caaataaata gaaactggaa cacgttcccg acgcagtgcg
    27121 ttcaggaacg gatcttgtaa agattgcccc ttagccattc tctcttttcc ttatatgctt
    27181 atttgtactt tgaacctttc gattctgaaa aaattgcgca cgatacgtct caattgtaca
    27241 cattcagcct gcgatagcac caacaacctg taatacttcg tcacgcgcct gttctggttt
    27301 ttcactgtca agccagtgaa ccccttccca accacgcagc caggttatct gccgcttcgc
    27361 caactgtctc gtggcgcaaa cacctcgata aaccatttca tcgtatgaga tttcgccttc
    27421 aaggtaagac cacatctggc gataacccac gcaacgaatg gaaggcaagt ccgtatgcaa
    27481 atctcctcgg gcaaaaagcg cccggacttc tgcttcaaaa cctgaagcca acatctgatg
    27541 aaaacgctgc tcaattcgtt gatggagcag ttcacggctc gccggggcga tggcgaactg
    27601 atgcacctga tacggtagag cgtctcctga cgtttgcgtc agttccgtta aagttttacc
    27661 cgaaatgaaa aaaacttcca gtgcccggga aagcctttgt ggatcatttg gatgaatcct
    27721 tgctgccgca actggatcga tctcctgaag ttgacgatgc aatgactccc aaccttgctc
    27781 tgccgcctgt tgctcaattc tggcccgcac ttccgggtct gccgacggta gcggcgacaa
    27841 cccttccagc aatgccttga aatacaacat cgtaccgccc actaacagtg ggatccgccc
    27901 cgccgcggtg atatcggcca tttccgccag cgcatcgcgg cgaaaatcag cagccgagta
    27961 agcctgcgac ggatcgcgaa tatccagcaa tcggtgcggc gcggcgagta actcttcagc
    28021 gttcggcttc gccgtcccga tatccatccc tttgtaaata agggcagaat caacgcttat
    28081 caactctact ggtaaaattt tacgcagctc aatggctaac gccgttttac cggaggccgt
    28141 cggccccatc aaaaaaatcg ccttaggcag gctcgcctta ctgatatcac tcatctttca
    28201 gggcttttat cgccggatgt aaatcaacag attgtaacag accacccggc ggcgttttca
    28261 caagttgcgg acataaccgt tccacgtccg ccagcagggt tatggcctgt gccattgacc
    28321 actgcgcatg ttcgctcatc agatttcgtg caatccactg cgcaatattg ccaggttcga
    28381 atacggactg cttcgccagg tagcctatca gttcaggaat caagatttgt aaattttgtt
    28441 ggcgtaaggg taaaggcacg gccctgatgg tcacatgctg tgcatctgac tggaaatcaa
    28501 tacccaattc cgccagggca gactgcgctt tttctaatgc cgatttttct tcgccagaaa
    28561 cttttagccg cagcggaatc agcaacggct gggcgcaaac tggcgcttca cccggcgtca
    28621 gttgcgcctg acgcagccaa cgttctgcca ctggcaaggc taaaagtgaa atgttgccgt
    28681 cgcgctccag caacgcacag tcggaatgga cgatcgtcag tacccgacca aaactctgac
    28741 tgttcgccgc aagtgcaggt tcctgcggtt ctggcgcttt tggttttggc atcggcgcgg
    28801 gcgtttgcaa aagctggcga tacacttcac cttgctgttt ctggtagcct ggctgcgcat
    28861 tcggccaggg ggcagccgga cgactgcctg aggagggcgc aggagtgtaa cgcggagcta
    28921 ctggctcacg aactgccggt tcagcaaaat gattgcgccc cgccgccacg cggttttccg
    28981 gaatagcgcg cggtgcaggt tgtggttcat cgtccagcgg tagcggcgtt tccagttgct
    29041 gttgtagcac gctcagcacg ccctgataga taaaatcatg caccagacgc gactgatgga
    29101 aacgcacttc gtgtttggcg gggtgcacgt tgacgtccac ctgatgtggg tcgatctcca
    29161 gatacagcac aaatgccggt tgttgatcgg cccccagttt gtcttcacag gcctggcgga
    29221 tcgcatgatt gatcaggcga tcgcgcatca tgcgaccgtt cacgtagcaa tactgaattt
    29281 ctgccagggc gggcgtggtg tgattcggat cggccaccca gccgcgcagg gagagatcgc
    29341 cgtgttgcca ttcaatcgcc agcgcttgtt cgagaaaagc ggtaccgcaa atcgcgccta
    29401 agcgccgttc tttttgcccg ccttccggca ctgcacggta ctgacgcaca attttaccgt
    29461 tatgcgacag gttgatcgtg acgtcgaaac gcgccagcgc aatgcggcga ataatttcat
    29521 cgatatggtt aaattcggtt ttctcggtgc gcaggaattt gcgccgcgcc ggggtgttgt
    29581 agaacagatc cagcacctcc agcgtcgttc ccaccggatg cgccgccggt ttaaccgtca
    29641 cgtccatatc gcgcccttcg gcataggcct gccaggcttc ctgttgttct gcggtgcgtg
    29701 aagtgagcgt caggcgggaa accgaactga tactcgccag cgcctcaccg cgaaagccca
    29761 agctgataat ggcttcgaga tcgtccagag aggcgatttt actggtggca tgacgcgcca
    29821 gcgccagcgc cagctcatct tttttgatac cgcagccgtt atcacgaatg cggataagtt
    29881 tcgccccgcc acgttcgata tcaatatcaa tgcgcgtcgc acctgcatcg aggctgtttt
    29941 ccaccagttc tttgactacc gacgcaggtc gctcgaccac ctcacctgcg gcaatctggt
    30001 tcgccagttg tggcggtaag acctgtattg gcatcaatcg tccttagttt ggcagcgtac
    30061 gatctggcgt cgtcaccgta ctggcagttt gtgccgttgc accctgcggc gcagattgca
    30121 tcggatgcgc aaggaaataa ttgcgcagac ctttataaat ggcttctgcc agctgttgtt
    30181 ggtaatcgtc gctcgccagc aaacgttctt cgctgttgtt gctgataaaa ccggtttcga
    30241 ccagtactga tgggatatcc ggcgaacgca gaacgccaag gctggcgtgt tctggtcgac
    30301 gtttatgaat ttcgccaatg cgttgcaact gactgatcat actggtcgct acatcatacc
    30361 ctacccgctg ggaatgaccg aactgtaaat ccagcaccgc ctggctcaaa taggggtcag
    30421 actgactgtt cgccagcaca tcgcccgctc cgcccagtag ctccgactgt ttctcatgct
    30481 gttccagcca gcttgccatc tcgctgtttg cacgacggtt agagagcacc catacggaag
    30541 cgccagtcgc actgcggttt ggtgcggcat cagcgtgaat cgacacgagg aaattggcgt
    30601 tttgcttacg tgccacatcg ctgcgcccca tcaccgaaat aaagtaatcc ccgtcacggg
    30661 ttaaaacgcc tttaaacatt ggatcgtcat tgagcaaagt acgtaattta cgtgcgatgg
    30721 cgatggtgac atttttctcc cgcgtaccac cggggccgat agcgccaggg tcctgaccgc
    30781 cgtgtcctgc atcaatagcg atgataattt tatcgccaat gttagccgtc gcacgcgctg
    30841 ccggacgcgt taccgtatta ctgctgataa cacccgtagt acggttactt tccgttttaa
    30901 acggattgcg cgccggttcg ctgacgcgag gtgcgacaac cgcaggcgtt tcaacgcgtt
    30961 tcgcaaccac aggcggcgga ggaggcggtg gcggcgcatc ggcgttaatc gtaaagacga
    31021 cagtgtaatt gctgccattc tgccgcttca ccgcttcggt tttaccattt tcggtaagat
    31081 cgaccaccag ccgtagcgtt tgtgcatctt taggcgttcc agagcgaatc gccttcacca
    31141 gattattgcc gctgaacaac aacggcagcc cctgaattac ccccgtttgt ttgatatcga
    31201 gcgccacggt gcgtttgctt tgatggctaa acgcataatc aggatcgcca ataaaactca
    31261 acgttatccg cgcctgttgg ttgccgttag aaacctgaat atcagagagc gtcgcggcac
    31321 ccacctgcgc gcacagcagc agcaacgtcg ctaccaacca ttttctgatg cgatacatca
    31381 tcccgccacc tttcaaaggt taaccggcta aacgcgccag caacaattca cccgcagagg
    31441 aaaccgcact cacgcgcgcc tcacggcctt gtgcctgata atcaatgtgt atttcgacat
    31501 ccgggtcagg aagaacacct gtaccttgtt gtggccactc caccaggcag atggcatcgt
    31561 tggcaaaata atcgcggatc cccataaact ccagctcctc gggatcggca aggcggtaca
    31621 aatcaaagtg ataaaccatt aaattgtcga gcgtataggg ttcgaccagc gtataagtgg
    31681 ggcttttgac attaccctga tgacccaggg cttgtaaaaa gccccggcta aaggtggttt
    31741 tacctgcgcc taaatcgcca tacagataga ttacggttgc gccatcgcag gctttcgcta
    31801 cccgctcgcc caggtctaat gttgcctgct catcagggag cggaattact cgattcatca
    31861 tggtttttat cagtcacttc cgggttaaca atacgctgta gcgtggaaaa gagatcggtt
    31921 gccagcatcc cgcgcgttcc aaaacgcgcc gccagtacgt cagctgccgc accgtgcgcg
    31981 acacagcccg cacaggctgc atcataaggg ctcatttttt gcccaagcaa tgcgccaata
    32041 ataccagaga gcacatcgcc catgccgccg ctcgccatgc ctgcatttcc gacatcaata
    32101 atgcctaaag cgtcagaatg ggcggcgacc acggttccgg cacctttcag caccgctacg
    32161 ccgccataac gttgtaccag acgttgggcg caatgtaagc ggtcactttc aatttcagcg
    32221 acggaacagc ctaacaaccg tgcggcctcg ccaggatgcg gcgtgatcac gcgattgtga
    32281 cgcttatcgg gattgattgc cagcaggttc aatgcatcgg catcccacaa catcggtttg
    32341 cgaaaattct caactttttg cagggctttt ttcccccact cttgctggcc cagaccggga
    32401 ccaatcacca ccacatcggc ccattccagg ctttcggtaa gagagtccat agtcagttca
    32461 tgcaccatca attctggtcg tgcagtcagc agcggcgcaa tgttctcact gcgggtcagt
    32521 actcggacta aaccagcacc agcacgcagc gccgcttccc ccgtcatacg aatagccccc
    32581 gccgtgccgt gatcgccacc gataatcacc agccgcccgt gatcgccttt atgcgaagtc
    32641 gggcgacgcg gtttcagcca gtgagaaagt tgttctgccg aaaaccgctg aattttcgtc
    32701 tcctgacctg ccagccagct atccagcccc agtgagtcaa aatgcagttg tcctgtaaca
    32761 tcccgcgctt ttccagtgag caagcctggt ttcagcgcaa taaaagtgat ggtgtgatcg
    32821 gcgttgatca ccgcgcctgg cgtagcgcca gtttcagcca gcaggccgga agggatatca
    32881 accgccacaa tcggcgcagg atgggaatta gcgtggtcga ttaactggct aatggattca
    32941 cgaggcgctt gctgtaatcc ggtaccgagc agcgcatcaa caatcagatc taccgattcg
    33001 ggccagacaa tattcgaagc atggatctcg cctcccgcgt ttaaccatgc ttcgcgtgcc
    33061 agcgcggcct cttccggcaa cggtttgtca ctttcctggg ccagcagcgt gacatcaata
    33121 ccgaccgctt tggccagtcg cgcgaccacg tagccatcgc cgccgttatt accatgaccg
    33181 cacagcacca gccagtggcg ggcgtcagga taagccgaac gacacacctg gaatgcggct
    33241 tcgccagcgc gaagcatcag ctcatagagt gtgagcccca gcgcatctgc cgcctcgcgt
    33301 tctccgcggc ggatatcgtc ggcgtaccag acggtgtgtg gtatacttat ggggtttttc
    33361 ttcattgtat ggtccgtcat gtcagagccc ctcgatctca atcagttagc gcaaaaaatt
    33421 aaacagtggg ggctggaact gggctttcag caggtaggta ttaccgatac cgatctcagc
    33481 gcgtccgagc ccaaactgca agcatggctg gacaaacaat accacggcga aatggactgg
    33541 atggcgcgtc acggtatgct gcgcgctcgc ccccatgagt tattgcctgg tacgctgcgc
    33601 gtgatcagcg tgcggatgaa ttaccttcct gctaacgccg catttgccag cacgctgaaa
    33661 aaccccaaac tcggctatgt tagccgttat gcgctgggcc gtgactatca caaacttctg
    33721 cgcaaccgac tcaaaaagct gggcgagatg attcagcaac attgtgtttc gctgaatttt
    33781 agaccgtttg tcgattctgc gcctattctt gagcgcccgt tagctgaaaa agctgggctc
    33841 ggctggacag gtaagcactc acttatcctc aatcgcgagg ccggctcgtt cttcttttta
    33901 ggcgaattgc tggtcgatat tccgctaccc gtggatcaac cagtcgagga aggatgcggt
    33961 aaatgcgtgg cctgtatgac gatttgcccg accggtgcca tcgtcgagcc atataccgtc
    34021 gatgctcgcc gctgtatctc ttatctcacc atcgaactgg aaggggcgat cccggtagag
    34081 ttgcgaccat taatgggaaa ccgtatttac ggttgcgatg actgccagct tatctgcccg
    34141 tggaatcgct attcgcaact cactacagaa gacgatttca gcccgcgtaa gccgctacac
    34201 gcaccggaac tcattgagtt attcgcctgg agtgaagaga agtttttaaa agtcacggaa
    34261 ggttcggcga ttcgccgtat aggtcacctg cgttggctgc gtaatattgc cgtagcctta
    34321 ggcaatgcgc cctgggatga aacgattctg gcggcgctgg aaagtcgtaa aggtgagcac
    34381 ccacttcttg atgagcacat agcgtgggcg attgcgcagc aaatcgagag acgaaatgcg
    34441 agcatagtcg aagtgcaatt accgaaaaaa cagcgtctgg ttcgggtgat tgaaaaaggg
    34501 ttaccgcgtg acgcctgatt catccacagc ttgtgaataa aaataaaaac gcattgcaat
    34561 tcaagccgga aaaaatcgtc aagtgatcga tacgacaaaa cgaaatctta atttttaact
    34621 tatctatcaa taggttaaaa aaatactatt caccgtgcga agtttctttg aaattaagat
    34681 tacggcctga ggctgtggat aactctgttt acaagagttt gtcagagaca acaaaaacca
    34741 gcaataacgc atcgcgtcgc tgtggatatt ttattgagag aagaatttgg agcgggaaac
    34801 gagactcgaa ctcgcgaccc cgaccttggc aaggtcgtgc tctaccaact gagctattcc
    34861 cgcgtactac ttaattttgc tttcgtaatt ttcgcatttc tgcgtcgtta cgggaggcgc
    34921 attatacgag aaatctttcc ctctgcaacc cccctaaaaa attttttttg agtttttatc
    34981 tcaagtgctg aaattatcgg caagacgttc aatttagcgt caaaatcacg ccaccgcaag
    35041 tggattacgg cgcttacgtg accaggaaaa aatttacagc ttgataaaat gctcgcggta
    35101 gtaagccagc tccgccaccg attcacggat atcatccatc gcctgatgcg tcccctgctt
    35161 ggtaaaacca tccagaattt ccggcttcca gcggcgcgcc agctctttca gggtgctgac
    35221 atcgagataa cggtagtgga agtaggcttc cagctccggc atatatttaa acaggaagcg
    35281 acgatcctgg ccgatgctgt taccgcaaat cggcgatttt cccgcaggca cccactgttt
    35341 taagaattcg agcgttgcca gttcagcttc acgatcgccc atcgtgctcg ctttcacgcg
    35401 ctccaccagc ccgctggcgg tatgggtgcg cacgttccag tcatccatca gcgccagctg
    35461 ttcatcggac tgatgtactg caatggtcgg cccttctgcc agaatattca ggttggcatc
    35521 ggtcaccagc gtggcaatct caataatgcg atcgcgctcg ggatccagac cggtcatctc
    35581 aagatcgatc caaatcaggt tgttttcatt ggcactcatg ctattttcca cccattcaca
    35641 gtgactatat tgatccacaa ttgcgtgtat catagatgtt ttgcccatca ggggcgacca
    35701 ggagtctgta cgattgagta aaaataaact ctccaaaggc cagcagcgcc gcgtgaacgc
    35761 caatcaccag cgtcgtctta aaacgtctaa ggagaagccc gactacgacg acaatctgtt
    35821 tggcgagcct gatgaaggta tcgtcatcag ccgctttggt atgcacgctg atgtggaatc
    35881 cgcagatggc gacgttcacc gctgcaatat tcgccgtacc atccgttcgc tggtgaccgg
    35941 cgaccgcgta gtctggcgtc cgggtaaacc ggcggcggaa ggcgtaaatg tcaaagggat
    36001 cgtggaagcg gtgcatgagc gcacttcagt gttaacgcgc ccggacttct acgatggcgt
    36061 gaaacctatt gccgccaaca tcgaccagat tgtcattgtc tccgccattt tgccggagct
    36121 gtcgctcaat attatcgacc gttacctggt ggcctgcgaa accttgcaga ttgagccgat
    36181 tattgtgctc aacaagatag acctgctgga cgacgaaggt atgaagttcg tcaacgagca
    36241 gatggatatc taccgcaata tcggttatcg cgtattgatg gtttccagcc atactcagga
    36301 tgggctgaaa ccgctggaag aggcgttgac cggacgtatc agcatttttg ccgggcagtc
    36361 tggcgtcggc aaatccagcc tgctgaacgc gctgctgggg ctgcaaaaag agatcctgac
    36421 caacgatgtc tctgacaact cgggtctcgg tcagcacacc acgaccgccg ctcggctgta
    36481 tcacttcccg cacggcggtg atgtgattga ctccccagga gtgcgtgagt tcggcctctg
    36541 gcacctggag ccggaacaaa tcactcaggg ctttgtcgaa ttccatgact acttaggtct
    36601 gtgtaaatat cgcgattgca aacacgatac cgatccgggc tgcgctatcc gggaagcggt
    36661 tgaggaaggg aaaatcgcgg aaacccgttt cgaaaactat caccgtattc tggaaagcat
    36721 ggcgcaggta aaaacgcgta aaaacttttc tgatacggat gactgacaat taagctaacc
    36781 gtcgttagaa tcgtcccttt ttttcaggat ccggcatgta ggccggatca ggaacgacaa
    36841 aacaatggcc tggaggctac cttgttaaat tcatttaaac tttcgctaca gtacattctg
    36901 ccgaaactat ggcttactcg cctggcgggt tggggcgcaa gcaagcgggc aggatggctg
    36961 acaaaactgg ttatcgatct gttcgttaaa tactacaagg tcgacatgaa agaggcgcaa
    37021 aagccggata ccgccagcta ccgcaccttt aacgaattct ttgtccgtcc gctgcgtgac
    37081 gaagtacgcc caatcgatac cgatccgaat gtactggtta tgcctgccga tggcgttatc
    37141 agccagttgg gtaaaatcga agaagataaa atcctgcaag ccaaaggcca caactacagc
    37201 ctcgaagccc tgctggcagg caactatctg atggcggacc tgttccgcaa cggtacgttt
    37261 gtgaccactt acctctcccc gcgtgactac caccgcgtac acatgccgtg caacggtatt
    37321 ctgcgtgaga tgatctacgt gccgggcgat ctcttttccg ttaaccatct caccgctcag
    37381 aacgtgccga atctgtttgc ccgtaacgaa cgcgtgatct gcctgttcga taccgaattt
    37441 ggcccaatgg cgcagattct ggtcggggcg acgattgtag gcagcattga gacggtctgg
    37501 gcgggcacca ttacgccgcc gcgcgaaggt atcatcaagc gctggacctg gcctgccggg
    37561 gaaaacgacg gttctgtggc actgctgaaa ggccaggaaa tgggtcgctt taaactcggt
    37621 tccaccgtta tcaacctgtt tgcaccgggt aaagtgaatc tggttgagca actggaaagc
    37681 ctgtctgtca cgaaaattgg ccagccgctg gcagtatcta ccgaaacctt tgttacgcca
    37741 gacgctgaac ccgccccgct tcctgctgaa gagatcgaag cagaacacga cgccagccca
    37801 ttggttgacg acaaaaaaga ccaggtctaa tccatcaaag gaaacgctga cgtgcgcctg
    37861 attatcactt ttctgatggc ctggtgcctc agttgggggg cgtacgccgc gacggccccc
    37921 gatagcaaac aaatctcaca agaactggag caggcaaaag cggcgaaacc cgcgcaaccg
    37981 gaagtcgtag aggcgctcca gtctgcctta aatgcgcttg aggaacggaa aggttccctt
    38041 gagcgcatca agcaatatca agaagtcatt gataattatc cgaaactctc cgctactctg
    38101 cgcgcgcaat taaacaacat gcgtgacgag ccgcgcagcg tgtcaccggg aatgtctacc
    38161 gacgcgctga atcaggaaat tctccaggtc agcagccagt tgctggataa aagccgtcag
    38221 gcccagcaag agcaggaacg cgcccgcgag attgccgatt cgctgaatca actgccgcaa
    38281 cagcaaaccg atgcccgccg tcagttaaat gaaatcgagc gccgcctggg gacgcttacc
    38341 ggcaattccc cgctcaatca ggcacaaaat ttcgcgttgc agtctgactc cgcacgcctg
    38401 aaagcgctcg tcgatgaact ggaactggcg cagctgtccg ccaataaccg ccaggaatta
    38461 gcgcgcttac gctcagagct ggcggaaaaa gagagccagc aactggatgc atatttgcag
    38521 gccttacgta atcagttgaa cagccaacgt cagcttgagg cggagcgggc gctggaaagt
    38581 accgaattac tggcagaaaa cagtgccgat ttgccgaaag atatcgtcgc gcaattcaaa
    38641 attaaccgcg aactatcggc agcgctgaat caacaggcgc agcggatgga tctcgttgcc
    38701 tcgcaacagc gtcaggctgc cagccagacg ttacaggtcc ggcaggcgtt gaatacgctg
    38761 cgtgaacagt cgcaatggct gggctcgtcc aacctgctcg gcgaagcgtt gcgggcgcag
    38821 gtggcacggc tgccggaaat gccaaaacca caacaacttg ataccgaaat ggcgcagttg
    38881 cgtgtgcaac ggttacgtta tgaggatctg cttaataaac agccgcagct aaggcaaatt
    38941 catcaggccg acggtcagcc gctgaccgcc gagcaaaacc gtattctgga agcacagcta
    39001 cgcactcagc gtgagttgct gaactcattg ttgcagggtg gagacacgct actgctggaa
    39061 ctgaccaagc tgaaagtctc caacgggcaa ctggaggatg cgctgaaaga ggtgaatgaa
    39121 gcgacgcacc gctatctgtt ctggacctct gacgtgcgcc cgatgaccat cgcctggccg
    39181 ctggaaatcg cccaggatct gcgtcgtctc atttcgctgg acaccttcag tcagttgggc
    39241 aaagccagtg tgatgatgct gaccagtaaa gagacgattt tgccgctgtt tggcgcgttg
    39301 attctggtcg gttgcagtat ttactcgcgc cgctatttta cccgttttct tgaacgttcg
    39361 gcggcgaaag tcggcaaagt gactcaggat cacttctggc tgacgttacg cactcttttc
    39421 tggtcgattc tcgtcgcgtc accgctgcct gtgctgtgga tgacactggg ttacggcttg
    39481 cgcgaggcgt ggccttatcc gctggcggtc gcgattggtg atggcgtaac ggccacagtg
    39541 ccgctgctgt gggtagtgat gatttgcgcc acctttgccc gcccgaacgg cttgtttatc
    39601 gctcattttg gctggccgcg cgaacgggtt tcccgtggga tgcgctacta cctgatgagc
    39661 atcgggctta ttgtgccact gattatggcg ctgatgatgt tcgataacct cgacgaccgc
    39721 gaattttccg gttcgctggg acggctttgc tttatcctca tttgcggtgc gttggcggtg
    39781 gtcaccctca gcctgaaaaa ggccgggatc ccgctgtatc tcaacaaaga aggcagcggc
    39841 gacaacatta ccaaccatat gctgtggaac atgatgatta gcgcaccgct ggtcgctatt
    39901 ctggcgtcgg cggtgggtta tctggcaacg gcacaggcgc tgttagcgag gcttgaaacc
    39961 tcggttgcca tctggttcct gctactggtg gtttatcacg ttatccgccg ctggatgctg
    40021 atccaacgcc gcaggctggc gtttgaccgg gcgaagcatc gccgggcaga gatgttagcg
    40081 caacgtgcgc gtggcgaaga ggaagcgcat catcacagta gcccggaagg ggcaattgaa
    40141 gtcgatgaaa gcgaagtcga tctcgatgcc ataagtgcgc aatccttgcg gctggtgcgc
    40201 tcaattttga tgttgatcgc cctgctttcg gtcattgtgc tgtggtcaga aatccattcc
    40261 gctttcggct tccttgaaaa tatttctctg tgggatgtca cttccacggt acagggcgta
    40321 gaaagtctgg agccgattac cctcggtgcg gtgctgattg ccattctggt gtttatcatc
    40381 accacgcagc tggtgcgcaa cctgcccgcg ctgctggaac tggcgatttt gcagcacctg
    40441 gatttaacgc cgggtacggg ctacgccatc accaccatca ccaaatatct gctgatgctg
    40501 attggcgggc tggtcggctt ctcaatgatt ggtattgagt ggtcgaaatt gcagtggctg
    40561 gttgccgcgc tcggtgttgg tctcggtttt ggtttgcagg aaattttcgc caactttatc
    40621 tctggcctga tcatcctgtt cgaaaaaccg attcgcattg gcgatacggt aacgatccgc
    40681 gatcttactg gtagcgtgac gaaaattaac acccgcgcca ccaccatcag cgactgggac
    40741 cgtaaagaga taatcgtgcc gaacaaggcg tttattaccg agcagtttat caactggtcg
    40801 ctctctgact cggtcacgcg cgtggtgttg acgattccgg cccctgccga tgccaacagt
    40861 gaagaagtga cggaaatcct gctcaccgca gcgcgtcgct gctcgctggt gatcgacaac
    40921 ccggcaccgg aagtcttcct ggtggatctg cagcagggga ttcagatttt cgagctgcgt
    40981 atttacgccg ctgagatggg tcatcgtatg ccgctacgcc atgagattca ccagctaatt
    41041 ctggcaggct tccatgccca cggtatcgat atgccattcc cgcccttcca gatgcgtctg
    41101 gaaagcctca acggtaaaca aacggggaga acattaactt ctgcgggcaa aggtcgtcag
    41161 gcgggaagtt tgtaatgcat gaagctgcca aatgatgtca acgtggctca tttagcagct
    41221 taacatcatc ttcagttatc actggccccg gagagtatca tccatacgca ttacttcctg
    41281 acaactcatc gccggagaga cgatgagttg caggatttca tatgatcagt cgagagctaa
    41341 ctcaggtttg ttcgccatgc gactgcaata gttctggtaa atcgccatcg ctaacagcga
    41401 gaagaagaca gggccgccaa tcatccacaa tgtgctgtcc cagtctccgg cctcaaccac
    41461 aggttgaatg atggtgaaga cgttcgcaaa tgtcaccacc agtacgacaa ccaccgtcgc
    41521 aatcattgcc gacaaatgcg ttttgaaaat cacaaacggt ctgtcgagat cctgacgtgc
    41581 tttaaagaac gggaaagcca gcgcgaggaa caggtaagga agtgtcatag acacgttcgc
    41641 catcaacgtc agcttgttaa agaacgccga tgcggtgcca ccgccaaacg aaaccagcag
    41701 gatgaagaca gtaaccagcc cgcactgcat ccacatggcg atagacggca tccccatcgc
    41761 attcaggcgc gtcatcggtt ctggccacaa cgctttcggc gtcccctgga tgatggcttt
    41821 cagcggtgaa tagcaaagcg taaagaacgc accggtataa gcgaggaaca tcgaaagtcc
    41881 ggtaatacgc gcaaaccata cgcccagcga caatgacgct tcaggtgaca aatgcagtgc
    41941 gttacccagc gtcaccccga ggctcttcat cagcacatag gtaatattgc cgaggttaac
    42001 ggaaccatta cttaatacct gctgccagtt tgtgctgacg ccccataaaa atattgccag
    42061 cgaataaccg attgaaataa caatagcggc aaaaacaata cctttggcaa agttcttttc
    42121 tggattttcc gttttatcga ccagaccacc aaccgcttca attccgccat aggcaaaaat
    42181 agcaaatacc acaaaagata gcattgccag accggactga taacctggat tcggtgatgt
    42241 caggaaatta atatcctgcg cgaaatgccc accatttaat aacaaaatag taatgcttac
    42301 taacagcaat actaaattca gacacattac tgcaataccg cccaccgcag taatgcgggc
    42361 aattttatta atcccctttg aagcaacgac ggtgaccaga atcatccatg ccactgccag
    42421 cagaccaacc acctgcgtag gctccagtcc ggcaatatgc cagtgctggg tcatgtcgct
    42481 accatagagg aatgttgaga acggtaccca aactttcgcg gaggtactca ccatccagat
    42541 gatataagag gaaaaccaca taaatgtacc aatgaaggca aaacgtggtc cgacactatt
    42601 attcatccag gaatagatac cgccttcttc tttgcgataa gcagctccca tttcagccat
    42661 cattaaggcg aatggaataa agaataacaa tgcagaaaat atataaaagg gaatcgcact
    42721 ataacccatt aagtaataag ccgatgggct attggcaaat ccaaatacgg aagtaaagat
    42781 catcaatatg agtcctatca gactcatctt ttttatcgtg tgaggcatga aaccatcctt
    42841 catttcagcg cgtgtataaa acgcgcccac tgaactgcac tgcccaacat tgagcgggca
    42901 gcgtaaaaac caatacagaa ttgatacctg gatgatatca aatatccagt cttaaattgt
    42961 ggcctttagc ggaaaaatga aaacatatgc tacagaatgg cgcttatcac gccattcttc
    43021 gcggttaatt cagtaatttt tcagaattat gcccggtcaa cgctaaaggc gatgacttca
    43081 gccagtgtct ccgcgcccag cgccaacatc accagacgat caacgcctaa tgccacgccg
    43141 gaacagtcag gcataccgac tttcaaggct tcaatcagat tctggtcaat ggggtgctgc
    43201 ggcaaaccgc gcgccgcgcg cttacggtta tcttgttcaa agcgttgttg ctgctcacgg
    43261 gcatccgtca attcatggaa accattcgcc agctcaatac ctttataata aacctcaaag
    43321 cgttcagcga cccgatgatc ttcggtactg atttgcgcca gtgatgcctg gctggctgga
    43381 aagtggtaca caaaggtcgg tttttcttta ccaatatttg gctctacgcc aaaggtaaac
    43441 agcaattgta gcaacgtgtc gcggtcttct tcggtatctg caacgttgct caaatccagt
    43501 ttcgctgcca cttcccgcag ttgcgttttg tcggcagaga gtgggtcaat ttccagataa
    43561 cgtaagaaag cttgttgata agaaaggctt tctgctgccg gacagtccag cacctgttgc
    43621 aagagatcgt ccacctcgtt catcaaccgg tacatatcat agtgcggtcg ataccactca
    43681 agcatagtga actcagggtt gtgataacgc cccatctctt cattacggaa gctgcggcac
    43741 agctggaata ccggcccaca accagcaacc agcaggcgct tcatatggta ttccgggctg
    43801 gtcattaacc agagattcat cccctgcgaa tgcccggggc caacgaaacg tgtctcaaac
    43861 gggaccaaat gaatatcggt taccgtcgcc tggctcatac aaggcgtctc cacctccagc
    43921 actccacgat cggcaaagaa acgacggatc tccgccataa tcgccgcgcg ttttaataag
    43981 ttaggaatgg atgcgctcgg ctgccaggat gccgtttcgc tcatagttaa atctccagtt
    44041 tttgacaagg gcacgaagtc tactcgcaac gcgacggcga gacaaatttt acgcaggaat
    44101 caaacaacgg tgggcagtga ctaaaaaaag cacgatctga tggtttagta attaaattaa
    44161 tcatcttcag tgataattta gccctcttgc gcactaaaaa aatcgatctc gtcaaatttc
    44221 agacttatcc atcagactat actgttgtac ctataaagga gcagtggaat agcgttcgca
    44281 gaccgtaact ttcaggcact taccctgaag tacggggctg tgggataaaa acaatctgga
    44341 ggaatgtcgt gcaaaccttt caagccgatc ttgccattgt aggcgccggt ggcgcgggat
    44401 tacgtgctgc aattgctgcc gcgcaggcaa atccaaatgc aaaaatcgca ctaatctcaa
    44461 aagtataccc gatgcgtagc cataccgttg ctgcagaagg gggctccgcc gctgtcgcgc
    44521 aggatcatga cagcttcgaa tatcactttc acgatacagt agcgggtggc gactggttgt
    44581 gtgagcagga tgtcgtggat tatttcgtcc accactgccc aaccgaaatg acccaactgg
    44641 aactgtgggg atgcccatgg agccgtcgcc cggatggtag cgtcaacgta cgtcgcttcg
    44701 gcggcatgaa aatcgagcgt acctggttcg ccgccgataa gaccggcttc catatgctgc
    44761 acacgctgtt ccagacctct ctgcaattcc cgcagatcca gcgttttgac gaacatttcg
    44821 tgctggatat tctggttgat gatggtcatg ttcgcggcct ggtagcaatg aacatgatgg
    44881 aaggcacgct ggtgcagatc cgtgctaacg cggtcgttat ggctaccggc ggtgcgggtc
    44941 gcgtttatcg ttacaacacc aacggcggca tcgttaccgg tgacggtatg ggtatggcgt
    45001 taagccacgg cgttccgctg cgtgacatgg aattcgttca gtatcaccca accggtctac
    45061 caggttccgg tatcctgatg accgaaggct gccgcggtga aggtggtatt ctggtcaaca
    45121 aaaatggcta ccgttatctg caagattacg gcatgggccc ggaaactccg ctgggcgagc
    45181 cgaaaaacaa atatatggaa ctgggtccac gcgacaaagt ttctcaggcc ttctggcacg
    45241 aatggcgtaa aggcaacacc atctccacgc cacgtggcga tgtggtttat ctcgacctgc
    45301 gtcacctcgg cgagaaaaaa ctgcatgaac gtctgccgtt catctgcgaa ctggcgaaag
    45361 cgtacgttgg cgtcgatccg gttaaagaac cgattccggt acgtccgacc gcacactaca
    45421 ccatgggcgg tatcgaaacc gatcagaact gtgaaacccg cattaaaggt ctgttcgccg
    45481 tgggtgaatg ttcctctgtt ggtctgcacg gtgcgaaccg tctgggctcc aactcgctgg
    45541 cggaactggt ggtcttcggt cgtctggccg gtgagcaagc tatggaacgc gcatctactg
    45601 ccggtaatgg caacgaagcg gcaattgaag cgcaggcagc tggcgttgaa caacatctga
    45661 aagatctggt taaccaggat ggcggcgaaa actgggctaa gatccgcgac gaaatgggca
    45721 tggccatgga agaaggctgc ggtatctacc gtacgccaga actgatgcag aaaaccatcg
    45781 acaagctggc agaattgcag gaacgcttca agcgcgtgcg catcaccgac acttccagcg
    45841 tgttcaacac cgacctgctc tacaccattg aactgggcca cggtctgaac gttgctgaat
    45901 gtatggcgca ctccgcaatg gcacgtaaag agtctcgcgg cgcgcaccag cgtctggacg
    45961 aaggttgcac cgagcgtgac gacgtcaact tcctcaaaca caccctcgcc ttccgcgatg
    46021 ctgatggcac gactcgcctg gagtacagcg acgtgaagat tactacgctg ccgccagcta
    46081 aacgcgttta cggtggcgaa gcggatgcag ccgataaggc ggaagcagcc aataagaagg
    46141 agaaggcgaa tggctgagat gaaaaacctg aaaattgagg tggtgcgcta taacccggaa
    46201 gtcgataccg caccgcatag cgcattctat gaagtgcctt atgacgcaac tacctcatta
    46261 ctggatgcgc tgggctacat caaagacaac ctggcaccgg acctgagcta ccgctggtcc
    46321 tgccgtatgg cgatttgtgg ttcctgcggc atgatggtta acaacgtgcc aaaactggca
    46381 tgtaaaacct tcctgcgtga ttacaccgac ggtatgaagg ttgaagcgtt agctaacttc
    46441 ccgattgaac gcgatctggt ggtcgatatg acccacttca tcgaaagtct ggaagcgatc
    46501 aaaccgtaca tcatcggcaa ctcccgcacc gcggatcagg gtactaacat ccagaccccg
    46561 gcgcagatgg cgaagtatca ccagttctcc ggttgcatca actgtggtct gtgctacgcc
    46621 gcgtgcccgc agtttggcct gaaccctgag ttcatcggtc cggctgccat tacgctggcg
    46681 catcgttata acgaagatag ccgcgaccac ggtaagaagg agcgtatggc gcagttgaac
    46741 agccagaacg gcgtatggag ctgtactttc gtgggctact gctccgaagt ctgcccgaaa
    46801 cacgtcgatc cggctgcggc cattcagcag ggcaaagtag aaagttcgaa agactttctt
    46861 atcgcgaccc tgaaaccacg ctaaggagtg caacatgacg actaaacgta aaccgtatgt
    46921 acggccaatg acgtccacct ggtggaaaaa attgccgttt tatcgctttt acatgctgcg
    46981 cgaaggcacg gcggttccgg ctgtgtggtt cagcattgaa ctgattttcg ggctgtttgc
    47041 cctgaaaaat ggcccggaag cctgggcggg attcgtcgac tttttacaaa acccggttat
    47101 cgtgatcatt aacctgatca ctctggcggc agccctgctg cacaccaaaa cctggtttga
    47161 gctggcacca aaagcagcca atatcattgt aaaagacgaa aaaatgggac cagagccaat
    47221 tatcaaaagt ctctgggcgg taactgtggt tgccaccatc gtaatcctgt ttgttgccct
    47281 gtactggtaa ggagcctgag atgattaatc caaatccaaa gcgttctgac gaaccggtat
    47341 tctggggcct cttcggggcc ggtggtatgt ggagcgcaat tattgcgccg gtgatgatcc
    47401 tgctggttgg tattctgctg ccactggggc tatttccggg tgatgcgctg agctacgagc
    47461 gcgttctggc gttcgcgcag agcttcattg gtcgcgtatt cctgttcctg atgatcgttc
    47521 tgccgctgtg gtgtggttta caccgtatgc accacgcgat gcacgatctg aaaatccacg
    47581 tacctgcggg taaatgggtt ttctacggtc tggctgctat cctgacagtt gtcacactga
    47641 ttggtgtcgt tacaatctaa cgcatcgcca atgtaaatcc ggcccgccta tggcggaccg
    47701 ttttgtatgg aaaccagacc ttatgttcaa aacgacgctc tgcaccttat taattaccgc
    47761 ctcttgctcc acatttgccg cccctcaaca aatcaacgat attgtgcatc gcacaattac
    47821 cccgcttata gagcaacaaa agatccccgg tatggcggtg gcggtaattt atcagggtaa
    47881 accttattac tttacctggg gctatgcgga catcgccaaa aagcagcccg tcacacagca
    47941 aacgttgttt gagttaggtt cggtcagcaa aacatttacg ggcgtgcttg gtggcgacgc
    48001 tattgctcga ggggaaatca agttaagcga tcccacaaca aaatactggc ctgaacttac
    48061 cgctaaacag tggaatggga tcacactatt acatctcgca acctacaccg ctggcggcct
    48121 gccattgcag gtgccggatg aggtgaaatc ctcaagcgac ttgctgcgct tctatcaaaa
    48181 ctggcagcct gcatgggctc caggaacaca acgtctgtat gccaactcca gtatcggttt
    48241 gttcggcgca ctggctgtga agccgtctgg tttgagtttt gagcaggcga tgaaaactcg
    48301 tgtcttccag ccactcaaac tcaatcatac gtggattaat gtactgtccg cagaagaaaa
    48361 gaactacgcc tggggatatc gcgaaggtaa ggcagtacat gtttcgccag gggcgttaga
    48421 tgctgaagct tatggtgtga agtcgaccat tgaagatatg gcccgctggg tgcaaagcaa
    48481 tttaaaacca tttgatatca atgagaaaac acttcaacaa gggatacaac tggcacaatc
    48541 tcgctactgg caaaccggcg atatgtatca gggtctgggc tgggaaatgc tggactggcc
    48601 gctaaatcct gacatcatca ttaacggcag tgacaataaa attgcactgg cagcacgccc
    48661 cgtaaaaccg attacgcccc caactcctgc agtacgcgca tcatgggtac ataaaacggg
    48721 ggcgaccggc ggatttggta gctatgtcgc gtttattcca gaaaaagagc tgggtatcgt
    48781 gatgctggct aacaaaaact atcccaatcc agcgagagtc gccgccgcct ggcagattct
    48841 caacgctcta cagtaaaatt tcatcgggtc cgaattttcg gaccttttct ccgcttttcc
    48901 ttgctgtcat ctacacttag aaaaaaacca gtaaggaaac atttatgcgc ctgctccctc
    48961 tcgttgccgc agcgacagct gcatttctgg tcgttgcctg cagttctcct acgccgcccc
    49021 gtggcgtgac cgtagtgaat aatttcgatg ctaaacgcta tctcggtacc tggtatgaga
    49081 ttgcccgttt tgatcaccgc tttgaacgtg gactggaaaa agtcaccgca acatacagcc
    49141 tgcgggatga cggcggcctg aatgtcatta ataaaggcta taaccctgac agaggaatgt
    49201 ggcaacagag tgaagggaaa gcgtacttta ccggcgcacc aactcgcgct gcgctgaaag
    49261 tgtcattctt tggtcctttc tatggcggtt ataacgttat tgcactcgat cgggaatacc
    49321 gccatgcgct ggtttgcggc ccggaccgcg actacctgtg gatactctcc cgcacgccaa
    49381 ccatttctga cgaagtgaaa caggagatgc tggcagtcgc gacccgggaa gggtttgatg
    49441 tcagtaagtt tatttgggta cagcagcccg gtagttagtg agtgctgagt ttcagaccaa
    49501 taatccccaa tacgattaac gccagactcg ccaggcgcat cgggttagcg gactcgccga
    49561 gcagcacaat gccggtgatg gccgcgccga ctgcgccaat acccgtccac acggcataag
    49621 ccgtccctac tggtaacgat ttcatcgccc aggcaagtag cgccatactg acaatcatcg
    49681 ccgtcacagt aataacactt ggcgtcaaac gactaaagcc gtgggtatat ttcaggccaa
    49741 cggcccatac cacttccagc agaccagcaa taactaagat aatccaggac atatcaggct
    49801 ccggagaatt ggggccgtcc ccggtgaaaa gaggcgtttg caggtcgtcc tgcaaagctg
    49861 atggttgaac ggatattttg ccaggtggca ggggaatttc aactattacc tttgtgacta
    49921 tcgcagaaaa aacaaacggc acgacacagc tgtcgtaccg ttattgctta ctgctgcgct
    49981 ttcgttgctg cgccagaaat cgcgttaccg ccatcagaaa tgtcttcacc aacgccacgc
    50041 gtggtgttgc aggcagttaa tactgttgaa agcaccagaa cagaaaagat cgctgcaatt
    50101 gtcttcttca ccataacgtc ttccttttag gtaatgttat ttatgtttgc ctatagcaaa
    50161 ttaataatag acaacatcac caaaaatgat ggaaatctga tgatttttcg gaagagaaga
    50221 aaaattagct ggcagcgcgg gagatggaat taccgagatg tttaatgtct tcaccaaaac
    50281 cgcgagcggt gttacagccc gtgagcagcg cactggcaag caaaacaaga acgataaggc
    50341 gtttcatcat ctctgacctg aataagtgat ggtgcagcct gcaggccgca ccacaaccgt
    50401 attacttcac gcgagagacg tattcaccag agcgggtatc cactttgatg acttcgccga
    50461 tctgcacgaa cagcggaact ttaaccacag cgccagtaga cagggtagct ggtttgccgc
    50521 cagtacctgc ggtatcacct ttcaggcccg gatcggtatc aacgatttcc agttcaacga
    50581 agttcggcgg agtaacggag atcggctgac cattccacag agttacgata cactctgcct
    50641 gatcaagcag ccatttcgcg ttgtcgccaa ttgcttttgc gtcagcagac agctgctcga
    50701 aagtttcgtt gttcatgaag tgccagaact caccgtcgtt gtacaggtaa gtcaggttca
    50761 tatcgacaac atcagcgcct tcagcggaat cagtagattt gaaggttttt tctacgcgag
    50821 taccggtcag cagacgacgc agtttaacgc gagcaaatgc ctggccttta cccggtttta
    50881 cgaattcact cgcttcaacc gcgtaaggtt cgccgtctaa catgatttta agaccagcac
    50941 gaaaatcgtt gctatagtac gttgccataa ggccctctga aatttgttaa ttggtagcta
    51001 agccacaaaa tggcgcatat tgtaacccta aataccccat ccagagaaga ttggttaacg
    51061 caacttgccg atgttgtgac cgatcctgat gaacttctgc gtcttttgaa tatagacgcg
    51121 gacgaaaaac tgttggccgg acgcagcgcc aaaaagcttt ttgccctgcg tgtgccccgc
    51181 tcatttatcg atcgcatgga gaaaggcgat ccggacgatc ctcttttgcg tcaggtactt
    51241 acctcgcaag atgagtttgt cgtcgcgccc ggattctcca ccgacccact ggaagaacag
    51301 cacagcgtag tgcctggttt gttgcataaa taccacaacc gggcgctttt gctggtcaaa
    51361 ggcggctgcg cggtaaattg ccgctattgc ttccgtcgcc acttccccta tgccgaaaat
    51421 cagggcaaca agcgtaactg gcaaactgca cttgagtatg ttgctgcgca tccggaactg
    51481 gacgagatga ttttctccgg cggcgatccg ctgatggcga aagatcacga gctggactgg
    51541 ttgctcacac aactggaagc catcccgcat atcaaacgtc tgcggattca cagccgtctg
    51601 ccgattgtga tcccggcacg catcacagat gcgctggttg aacgcttttc tcattctacg
    51661 ctgcaaatct tgctggtgaa tcacattaac catgccaatg aggtagatga aacattccgt
    51721 caggcgatgg ctaagttgcg ccgggtaggc gttactttgc tgaatcagag cgttctgtta
    51781 cgtggtgtga acgataacgc gcaaacgctg gcaaacctga gtaatgcgtt gttcgatgcg
    51841 ggcgtgatgc cgtattacct gcatgtgctc gataaagtac agggcgcggc gcattttatg
    51901 gtgagtgatg acgaagcacg gcagattatg cgtgagttgc tgacactggt gtcgggatat
    51961 ctggtgccta aactggcgcg agaaattggc ggcgaaccca gcaaaacgcc gctggatctc
    52021 cagctacgcc agcagtaact gattaaacag ggaagtttaa tctttgcccg ttgcataacc
    52081 tttaattatt catatacatt gctgttgtta ctctttatat aaccaacacc aataattaac
    52141 ctttcttttc tgtttatata gagtgagcac ggctatttat gttattttaa caactattac
    52201 taccaagccc atttatctgg cttataaact aaaattaatt atttaattga gaaatggtta
    52261 gggagaacct acatggccat aagcatcaag ggtgttaata ccggtgttat tcgcaagagt
    52321 aataatttca ttgcactggc gctgaaaatt aaagagcctc gcaataaaga atcgttgttc
    52381 tttctgtctg tcatggaact gcgcgacctt ctgattgcgc tggaaagccg tttgcatcaa
    52441 aagcataaac tggatgctgc tgcacgcctt cagtatgagc aagctcgcga taaagtcatt
    52501 aagaaaatgg cagaaaatat cccagaaatt ctggttgatg agcttaaaaa tgccgatatt
    52561 aatcgtcggg ttaacacgct ggaacttaac gataatcagg gcgaaaatct taccttcgta
    52621 ttaacgctac atgacggtag caaatgtgag ttagtcatca atgaattgca gattgaaatg
    52681 ctggcgcgag caatcattca tgcaattaat aatgcggaaa tgcgtgaact ggcattacgt
    52741 attacctcac tgttagattt cctgccgtta tacgacgttg actgccagga caatggcaat
    52801 ctggaatatg acacctattc ccaaccggaa tggaaacata acttgttcaa ccattatctg
    52861 gcggtgcttt accgctttaa agatgaaagt ggcaaagaac aatttagcgg cgcagtggtg
    52921 aaaacgcgtg aagcaacgcc gggtaaagaa gtggaggcga tcactcgccg aatgcttgat
    52981 ttcagccccc gactgaaaaa actcgcgggt gtgccatgtc aggtctatgt tcgcaccgta
    53041 gcggcaaata acgcccaacc gctaacccag gatcaatgct tacgcgcgct gcatcactta
    53101 cgtgttcaat ccaccagcaa aactgcaccg caggcgaaat aatcccatct gttttactac
    53161 gaggctggaa gtatccagcc tctggatccc atcagttcgg gcacttatat acctggccga
    53221 taatctggct atccgtcggg acaaaactgg acaacattcc ctgcgacggg ctgctgatgc
    53281 cataaatcac gttaccgccc attgcagccg cctggttgcg cagatcgttt gctgcgccgc
    53341 gcatagaacc gccttcttca ccgtgttgcc cggaaagcca gttgctttgc ttacctgtcg
    53401 cagtaccaat cagctggcac tctgcgcctg gctgctcgtc cacaatgcgt acactctgac
    53461 cggcagcact caattcgttg ctggagctac aacccgccat cagtagcgcg gcaccgacaa
    53521 tccctgctaa gtattttacg tgcatgttat tccccataat caatgagctg gacgccactc
    53581 gcgtctgtgt gtgaatctta tactaaaaag atgactaaaa gaaaaacccc cagacatttc
    53641 tgcctgaggg tttgtttatt tctgcgaggt gcagggcaat tacatcatgc cgcccatgcc
    53701 acccatgccg cccataccgc cagcagcgcc taagtcagct gcatcatttt tcggcaggtc
    53761 ggtaaccatg cactcggtgg tgatcatcag gccagccaca gaagccgcgt actgcagagc
    53821 agaacgagtt actttggttg gatccaggat acccatgtcg atcatgttgc cgtattcttc
    53881 ggttgctgcg ttgtaaccgt agttgccgtc gccgccttta acagtgttag caacaacaga
    53941 cggttcttcg ccgcagttca ggacgatctg acgcagcgga gcctccattg cacgcagtgc
    54001 aactttgata cccacgttct ggtcttcgtt ctgaccacgc aggtcagcca gtttagacgc
    54061 tacgcggatc agcgcaacac caccaccagc aaccacgcct tcttctaccg cagcacgggt
    54121 cgcgtgcagg gcgtcttcaa cgcgtgcttt tttctctttc atttcaactt cggtagcagc
    54181 acctactttg ataactgcaa cgccgcctgc cagtttcgct acgcgctcct gcagtttttc
    54241 acggtcgtag tcagaagttg cttcttcaat ctgctgacgg atctgagcaa cacggccctg
    54301 gattgcagct tcttcgccca cgccatcgat gatggtggtg gtgtctttgt tgatcacaac
    54361 acgtttagcc tgacccaggt cttccagggt tgctttttcc agctccatac cgatctcttc
    54421 agagattacg gtaccgccag tcagggttgc gatatcctgc agcatagctt tacgacgatc
    54481 gccgaagccc ggagctttaa ccgcagcaac tttcacgatg ccacgcatgg tgttaacaac
    54541 cagagttgcc agcgcttcgc cttctacatc ttcagcgatg atcagcagcg gtttgcctgc
    54601 tttggcaaca gcttcgagaa ccggcagcat ttcgcggatg ttggagattt tcttgtcagc
    54661 cagcaggatg aatgggcttt ccagttctac tgcgccagtt tccggcttgt tgatgaagta
    54721 aggagacagg tagccacggt cgaactgcat accttcaacc acgtccagtt cgtcctgcag
    54781 accggtaccg tcttcaacgg tgataacgcc ttctttaccg actttgtcca tcgcttcagc
    54841 gatcagttta cctacggttt cgtcggagtt agcggagatg gtaccaacct gagcaatcgc
    54901 tttagagtca gagcacggta cggacagcgc tttcagttct tcaactgcag cggtaacagc
    54961 tttgtcgata ccacgtttca ggtccatcgg gttcatgccc gcagcaacag ctttcagacc
    55021 ttcagtgatg atagcctgag ccagtacggt tgcagtggtg gtaccgtcgc ctgcagcgtc
    55081 gttcgcttta gaggcaactt ctttcaccat ctgcgcaccc atattttcga acttgtcttc
    55141 cagttcgatt tcacgagcaa cggaaacacc atctttggtg atggtcggtg caccgaaaga
    55201 tttatccaga actacgttac ggcctttcgg accgagggta actttcactg catctgccag
    55261 tacgtttacg ccgcgcagca ttttcacacg agcgtcgtta ccgaatttta cgtctttagc
    55321 tgccattatc tttattcctt aaattcgtat gttcagtgtc gtgcgcggat tacgcttcaa
    55381 caattgccag aatgtcgctt tcggacatga tcaacacttc ttcattgtcg atcttctcag
    55441 atttcacacc gtagccatcg ttgaaaataa cgatgtcgcc aactttcaca tccagcggct
    55501 tcacttcgcc attttcaagg atacggccat tgccgacagc cagcacttcg ccgcgggtgg
    55561 atttagccgc tgcagagccg gtcagaacga tgccgccagc agatttagtt tcaacttctt
    55621 tacgcttgac gatcacgcga tcatgcaatg gacgaatatt cattgataac tctcctttga
    55681 gaaagtccgt atctgttatg ggtgacgccg gagcttacgt ggtttcccgg ctggtgacca
    55741 gagaaatggg gatgaggctt cgccccttca agggggaaaa agaaaaaaaa ttctgatcag
    55801 cacaaaatcg ggtgaaaacc ctgattcacc tcacatttca tcgcaatttc ttcatcaccg
    55861 tcataagcga atctgattgt gctaccatcg aaaatctacg cagttgccca taatttgggc
    55921 gcaatcggac atcaacccat gagtggactc aaacaagaac tggggctggc ccagggcatt
    55981 ggcctgctat cgacgtcatt attaggcact ggcgtgtttg ccgttcctgc gttagctgca
    56041 ctggtagcag gcaataacag cctgtgggcg tggcccgttt tgattatctt agtgttcccg
    56101 attgcgattg tgtttgcgat tctgggtcgc cactatccca gcgcaggcgg cgtcgcgcac
    56161 ttcgtcggta tggcgtttgg ttcgcggctt gagcgagtca ccggctggtt gtttttatcg
    56221 gtcattcccg tgggtttgcc agccgcgcta caaattgccg ccgggttcgg ccaggcaatg
    56281 tttggctggc atagctggca actgttgttg gcagaactcg gtacgctggc gctggtgtgg
    56341 tatatcggta ctcgcggtgc tagttccagt gctaatctac aaacagttat tgccggactt
    56401 atcgtcgcgc tgattgtcgc tatctggtgg gcgggcgata tcaaacctgc gaatatcccc
    56461 ttccctgcac ctggtaatat cgaacttacc gggttatttg ctgcgttatc agtgatgttc
    56521 tggtgctttg tcggtctgga ggcatttgcc catcttgcct cagaatttaa aaatccagag
    56581 cgtgattttc ctcgtgcttt gatgattggt ctgctgctgg caggattagt ctactggggc
    56641 tgtacggtag tcgtcttaca cttcgacgcc tatggtgaac aaatggcggc ggcagcatcg
    56701 cttccaaaaa ttgtagtgct gttgttcggt gtaggagcgt tatggattgc ctgcgtgatt
    56761 ggctatctgg cctgctttgc cagtctcaac atttatatac agagcttcgc ccgcctggtc
    56821 tggtcgcagg cgcaacataa tcctgaccac tacctggcac gcctctcttc tcgccatatc
    56881 ccgaataatg ccctcaatgc ggtgctcggc tgctgcgtgg tgagcacgct ggtgattcat
    56941 gctttagaga tcaatctgga cgctcttatt atttatgcca atggcatctt tattatgatt
    57001 tatctgttat gcatgctggc aggttgtaaa ttattgcaag gacgttatcg actactggcg
    57061 gtggttggcg ggctgttatg cgttctgtta ctggcaatgg tcggctggaa aagtctctat
    57121 gcgctgatca tgctggcggg gttatggctg tttctgccaa aacgaaaaac gccggaaaat
    57181 ggcataatca cataatccgg cgtttcgaca ttaatcctgg cgatcgtctt tatgatcaag
    57241 gcggtcgcgc tcatcatcct ttcgctggta ctcaccatca aaagtattac cgccaccggt
    57301 cccggcgcta aaaccgccgc ctggcatgcg agaaaagcgc aaatgcggca tcaacttcac
    57361 tgtcagatgc ttttgcaccg gcggcaataa aagcagaaga ccgaggaagt cggtgaaaaa
    57421 gccaggtaat aaaagcagca aaccggcaat gatcagcgaa acacttttaa tcatctccgc
    57481 cgctgggttt tcacccgccg ccattttttg ctgcatcagc acgaaattct taaagccctg
    57541 gttgcgtacc agtgacatac cgataactga cgtgaatata accagcacga gggtcagcaa
    57601 tacccccaat acatgggcaa cctgaataaa gattgaaatc tcaatataga cataaaggaa
    57661 aatggcaata aaaggtaacc agcgcaaagg tttctcctgt aatagcagcc ggttaacccc
    57721 ggctacctga atgggttgcg aatcgcgttc agcttatatt gtggtcatta gcaaaatttc
    57781 aagatgtttg cgcaactatt tttggtagta atcccaaagc ggtgatctat ttcacaaatt
    57841 aataattaag gggtaaaaac cgacacttaa agtgatccag attacggtag aaatcctcaa
    57901 gcagcatatg atctcgggta ttcggtcgat gcaggggata atcgtcggtc gaaaaacatt
    57961 cgaaaccaca tatattctgt gtgtttaaag caaatcattg gcagcttgaa aaagaaggtt
    58021 cacatgtcaa acaacattcg tatcgaagaa gatctgttgg gtaccaggga agttccagct
    58081 gatgcctact atggtgttca cactctgaga gcgattgaaa acttctatat cagcaacaac
    58141 aaaatcagtg atattcctga atttgttcgc ggtatggtaa tggttaaaaa agccgcagct
    58201 atggcaaaca aagagctgca aaccattcct aaaagtgtag cgaatgccat cattgccgca
    58261 tgtgatgaag tcctgaacaa cggaaaatgc atggatcagt tcccggtaga cgtctaccag
    58321 ggcggcgcag gtacttccgt aaacatgaac accaacgaag tgctggccaa tatcggtctg
    58381 gaactgatgg gtcaccagaa aggtgaatat cagtacctga acccgaacga ccatgttaac
    58441 aaatgtcagt ccactaacga cgcctacccg accggtttcc gtatcgcagt ttactcttcc
    58501 ctgattaagc tggtagatgc gattaaccaa ctgcgtgaag gctttgaacg taaagctgtc
    58561 gaattccagg acatcctgaa aatgggtcgt acacagctgc aggacgcagt accgatgacc
    58621 ctcggccagg aattccgcgc tttcagcatc ctgctgaaag aagaagtgaa aaacatccaa
    58681 cgtaccgctg aactgctgct ggaagttaac cttggcgcaa cagcaatcgg tactggtctg
    58741 aacacgccga aagagtactc tccgctggca gtgaaaaaac tggctgaagt cactggcttc
    58801 ccatgcgtac cggctgaaga cctgatcgaa gcgacctctg actgcggcgc ttatgttatg
    58861 gttcacggcg cgctgaaacg cctggctgtg aagatgtcca aaatctgtaa cgacctgcgc
    58921 ttgctctctt ctggcccacg tgccggcctg aacgagatca acctgccgga actgcaggcg
    58981 ggctcttcca tcatgccagc taaagtaaac ccggttgttc cggaagtggt taaccaggta
    59041 tgcttcaaag tcatcggtaa cgacaccact gttaccatgg cagcagaagc aggtcagctg
    59101 cagttgaacg ttatggagcc ggtcattggc caggccatgt tcgaatccgt tcacattctg
    59161 accaacgctt gctacaacct gctggaaaaa tgcattaacg gcatcactgc taacaaagaa
    59221 gtgtgcgaag gttacgttta caactctatc ggtatcgtta cttacctgaa cccgttcatc
    59281 ggtcaccaca acggtgacat cgtgggtaaa atctgtgccg aaaccggtaa gagtgtacgt
    59341 gaagtcgttc tggaacgcgg tctgttgact gaagcggaac ttgacgatat tttctccgta
    59401 cagaatctga tgcacccggc ttacaaagca aaacgctata ctgatgaaag cgaacagtaa
    59461 tcgtacaggg tagtacaaat aaaaaaggca cgtcagatga cgtgcctttt ttcttgtgag
    59521 cagtaactta aaaacaacaa tctaatatca acttgttaaa aaacaaggaa ggctaatatg
    59581 ctagttgtag aactcatcat agttttgctg gcgatcttct tgggcgccag attgggggga
    59641 ataggtattg gttttgcagg cggattgggg gtgctggttc ttgccgctat tggcgttaaa
    59701 cccggtaaca tcccgttcga tgtcatttcc attatcatgg cggttatcgc cgctatttct
    59761 gccatgcagg ttgctggcgg tctggactat ctggttcatc agacagaaaa gctgctgcgc
    59821 cgtaacccga aatacatcac gatcctcgca ccgatcgtaa cctatttcct gacaatcttt
    59881 gctggtactg gcaacatctc tctggcgaca ctgccagtta tcgctgaagt tgcgaaggaa
    59941 caaggcgtta aaccttgccg tccgctgtct actgcagtgg tatccgcgca gattgcgatc
    60001 accgcatcgc caatctcagc ggcagtggtt tacatgtctt ccgtaatgga aggtcatggc
    60061 atcagctacc tccatctgct ctccgtggtc atcccgtcca ccctgctggc ggttctggtg
    60121 atgtccttcc tggtcactat gctgttcaac tccaaactct ctgacgatcc gatttatcgc
    60181 aagcgtctgg aagaaggcct ggttgaactg cgcggtgaaa agcagattga aatcaaatcc
    60241 ggtgcaaaaa cgtccgtctg gctgttcctg ctgggcgtag ttggcgtggt tatctatgca
    60301 atcatcaaca gcccaagcat gggtctggtt gaaaaaccgc tgatgaacac cactaacgca
    60361 atcctgatca tcatgctcag cgttgcaact ctgaccaccg ttatctgtaa agtcgatacc
    60421 gacaacatcc tcaactccag caccttcaaa gcaggtatga gcgcctgtat ttgtatcctg
    60481 ggtgttgcgt ggctgggcga tactttcgtt tccaacaaca tcgactggat caaagatacc
    60541 gctggtgaag tgattcaggg tcatccgtgg ctgctggccg tcatcttctt ctttgcttct
    60601 gctctgctgt actctcaggc tgcaaccgca aaagcactga tgccgatggc tctggcactg
    60661 aacgtttctc cgctgaccgc tgttgcttct ttcgctgcgg tgtctggtct gttcattctg
    60721 ccgacctacc cgacgctggt tgctgcggta cagatggatg acacgggtac tacccgtatc
    60781 ggtaaattcg tcttcaacca tccgttcttc atcccgggta ctctgggtgt tgccctggcc
    60841 gtttgcttcg gcttcgtgct gggtagcttc atgctgtaat gatcaatcgc ggggcgttca
    60901 cgccccgctt tctttcccgc cgactaacat ccttcccccg tccgttgtat agtgacctct
    60961 ctcttgcggt tccatctgtt cttgcgaggt gtttatgctt gatgaaaaaa gttcgaatac
    61021 cgcgtctgtc gtggtgctat gtacggcacc ggatgaagcg acagcccagg atttagccgc
    61081 caaagtgctg gcggaaaaac tggcggcctg cgcgaccttg atccccggcg ctacctctct
    61141 ctattactgg gaaggtaagc tggagcaaga atacgaagtg cagatgattt taaaaactac
    61201 cgtatctcac cagcaggcac tgctggaatg cctgaagtct catcatccat atcaaacccc
    61261 ggaacttctg gttttacctg ttacacacgg agacacagat tacctctcat ggctcaacgc
    61321 atctttacgc tgatcctgct actttgcagc acttccgttt ttgccggatt attcgacgcg
    61381 ccgagacgtt cacaatttgt ccccgcggat caagcctttg cttttgattt tcagcaaaac
    61441 caacatgatc tgaatctgac ctggcagatc aaagacggtt actacctcta ccgtaaacag
    61501 atccgcatta cgccggaaca cgcgaaaatt gccgacgtgc agctgccaca aggcgtctgg
    61561 catgaagatg agttttacgg caaaagcgag atttaccgcg atcggctgac gcttcccgta
    61621 accatcaacc aggcgagtgc gggagcgacg ttaactgtca cctaccaggg ctgtgctgat
    61681 gccggtttct gttatccgcc agaaaccaaa accgttccgt taagcgaagt ggtcgccaac
    61741 aacgcagcgt cacagcctgt gtctgttccg cagcaagagc agcacaccgc gcaattgccc
    61801 ttttccgcgc tctgggcgtt gttgatcggt attggtatcg cctttacgcc atgcgtgctg
    61861 ccaatgtacc cactgatttc tggcatcgtg ctgggtggta aacagcggct ctccactgcc
    61921 agagcattgt tgctgacctt tatttatgtg caggggatgg cactgactta cacggcgctg
    61981 ggtctggtag ttgccgccgc agggttacag ttccaggcgg cgctacagca cccatacgtg
    62041 ctcattggcc tcgctatcgt ctttaccttg ctggcgatgt caatgtttgg tttgtttacc
    62101 ctgcaactcc cctcttcgct gcaaacgcgc ctcacgctga tgagcaatcg ccaacagggc
    62161 ggctcacctg gcggtgtgtt tgttatggga gcgattgccg gactgatctg ttcaccatgc
    62221 accaccgcac cgcttagcgc gattctgttg tatatcgccc aaagcgggaa catgtggctg
    62281 gggggcggca cgctttatct ctatgcgttg ggcatgggcc tgccgctgat gctaataacc
    62341 gtctttggta accgcctgct gccgaaaagc ggcccgtgga tggaacaagt caaaaccgcg
    62401 tttggttttg tgatcctcgc actgccggtc ttcctgctgg agcgagtgat tggtgatata
    62461 tggggattac gcttgtggtc ggcgcttggt gtcgcattct ttggctgggc ctttatcacc
    62521 agcctacagg ccaaacgcgg ctggatgcgc gtggtgcaaa taatcctgct ggcagcggca
    62581 ttggttagcg tgcgcccact tcaggattgg gcatttggtg cgacgcatac cgtgcaaact
    62641 cagacgcatc tcaactttac acaaatcaaa acggtagatg agttaaatca ggcgctcgtt
    62701 gaagccaaag gcaaaccagt gatgttagat ctctatgccg actggtgcgt cgcctgtaaa
    62761 gagtttgaga aatacacctt cagcgacccg caggtgcaaa aagcgttagc agacacggtc
    62821 ttacttcagg ctaacgtcac tgccaacgac gcccaagatg tggcgctgtt aaagcatctt
    62881 aatgtccttg gcctaccgac aattctcttt tttgacggac aaggccagga gcatccacaa
    62941 gaacgcgtca cgggctttat ggatgctgaa accttcagcg cacatttgcg cgatcgccaa
    63001 ccgtgaacga cacttgcagt gggaaagacg gaggaaaata gcgtgcaacg tgaagatgta
    63061 ctgggagaag ccctgaaatt attagaatta caagggattg ccaacaccac gctggagatg
    63121 gttgctgaac gtgtggatta tccactggac gagctacgcc gcttctggcc agacaaagag
    63181 gcaatcctct acgatgcgct gcgttatctt agccaacaga tagatgtctg gcgtcgtcag
    63241 ctgatgctgg acgaaacgca aaccgccgaa caaaagttgc tggcacgtta tcaggcgtta
    63301 tcggagtgcg ttaaaaacaa ccgctatccg ggctgtctgt ttatcgctgc ctgtacgttt
    63361 tatcccgatc ctggccaccc tattcatcaa ctggccgatc agcaaaaaag cgcggcctac
    63421 gatttcaccc acgaactgtt aaccacgctg gaagttgacg atccggcgat ggtagcaaag
    63481 cagatggaac tggtgctgga aggctgttta agccgaatgc tggtgaatcg tagccaggcg
    63541 gatgtcgaca ccgcacatcg gctggcggaa gatatcctgc gcttcgcccg ctgccgtcag
    63601 ggtggtgcac tgacctgaca gaaacacaga aaagaagcga tttgccgcaa tcttaagcag
    63661 ttgaatcgct tttactgaaa ttaggttgac gagatgtgca gattacggtt taatgcgccc
    63721 cgttgcccgg atagctcagt cggtagagca ggggattgaa aatccccgtg tccttggttc
    63781 gattccgagt ccgggcacca aattcatatc aacggacctc cacggaggtc cgtttttcgt
    63841 ttcagaacgc cacaatttaa gcgttctgcc tacaaatcaa ttctaccgaa ctcaaccaga
    63901 ttccccccac atcaacccca ttgtgtgggt ataattgcgg gtatacccca gttcgacaga
    63961 atttgtaccc tctttaacgc attcagaagg ctgtactatg gcactgactg acgcaaaaat
    64021 ccgggctgca aagcccactg acaaggctta taaactcact gacggggctg gcatgtttct
    64081 gctggttcat cctaatggtt cccgttactg gcgtctccgt tatcgtattc tgggtaagga
    64141 gaagactctg gcacttggtg tgtatccaga agtttctctc tccgaagctc gtacaaaacg
    64201 ggatgaggcc cgaaaactga ttttggaggg gattgaccct tgcgaacaga aaagagctaa
    64261 aaaagtagtc cctgatttac agctctcttt tgaacatatt gcacgacgct ggcatgccag
    64321 taataaacaa tgggcgcaat cacacagcga taaagtactc aaaagcctcg agacacacgt
    64381 tttccccttt atcggcaaca gggatatcac cacactcaat accccggacc tgcttatccc
    64441 tgttcgtgct gcagaagata aacagattta tgaaatcgcc agtcgtctgc agcaaaggat
    64501 atctgctgta atgcgttatg ccgtacagtc tggcatcatc agatataatc ctgctctgga
    64561 tatggctggc gcattgacca ctgtaaaacg ccagcatcgc cccgctcttg atctttcacg
    64621 tcttcctgaa cttttgtcgc gtattgacag ttataagggg cagcctgtca cccggcttgc
    64681 cgttatgctg aatctgctgg tgtttattcg ttccagtgaa ctcagatatg cccgctggtc
    64741 agaaattgat attgaaaatg ccatgtggac cattcctgcc gaacgcgagc ctctgccagg
    64801 tgtgaaatac tcacaccggg gttccaagat gcgaacacca catcttgtgc cactcagcaa
    64861 gcaggctgta gccatactga cagaacttca gacatgggct ggtgaaaatg gtctggtctt
    64921 tacgggagca catgacccgc ataaaccaat cagtgaaaac accgtaaata aagccctcag
    64981 ggtgatgggg tatgacacaa ccctggatat ctgtgggcat ggattcagga cgatggcatg
    65041 tagcgcgtta atagaatcag gattgtggtc ccgtgatgca gtggaacgtc agatgagtca
    65101 tcaggagcgt aatggtgtac gtgctgctta cattcataaa gcagaacatc tggaagaacg
    65161 ccgactgatg ctacagtggt gggccgattt tctgaatgca aacagagaaa gatttatcag
    65221 tccatttgaa tatgcaaaga ttaataatcc gttaaaacag taatcatccc gggcaaatgc
    65281 ccgggaacta ctccaggact attttctttg ttaaaaaaag acaaacggta tgaactgatg
    65341 tatttactgt ttacctgatt gcaccctaca ggggattatc agaatccacg gttattcatt
    65401 atttatatat cttcaataaa aaggaacctc aaaaaaatcc cgcacccaca gggtgatgcg
    65461 ggataactga cgtaaggaat gctgccggga tttggtggtc ccttgtgctg atatgaatac
    65521 aggttctatt ctatacagaa tccttttcag tacaagagac tgtattacag tttgccatat
    65581 atgattacct gtggtccgga agaataagtg gctgcggttt cagactgtct tcctgtacat
    65641 acctctctcc gttaaaaacc ataacgggtt cattatcttc gtctgtcagc ggattgaatg
    65701 gcggtatatt ttcggtacga ataccggtca gccactgaaa aatgcctgcg aaattacggg
    65761 cactgatttt cctgctgacg gactgatgag acgtgatgtc actggcggta ataatcaggg
    65821 gaacgctgta gcccccctgc acatgaccat catgatgaac aggattagca ctgtcgctga
    65881 ccgacagccc atggtcagaa aagtaaagca ttgcaaagtg acgggaatgc cggcgaagga
    65941 taccatcaag ctgaccaaga aagttatcca gtttactgat gctggcaaga taacaggcaa
    66001 tttttcggga atactgctcc aggtaattat tctgccagga gtgaagccga tcacacgggt
    66061 tcggatgaga ccccatcatg tgcaggaaaa tcaccttcgg agtggatgta tctgccagcg
    66121 cacgttctgt ttcctgtaac aacaacatgt catccgtttt acgggaagca aagctgcctt
    66181 tcttgaggaa aacagtatgg tccgcatcag aagcaataac agagatgcgt gtgtcatgct
    66241 ctcccagttt tccctgattg gatatccacc atgtgctgta tcctgctttt gctgccagcg
    66301 ccaccacgtt gttgccggaa tcagggttct gctcatagtc ataaatcagt gtccggctca
    66361 gggaaggcac ggtgctggct gctgccgatg tataaccgtc aataaataaa ccgggagccg
    66421 tattcagcca tggtgtggtt ggctcgggat aaccatatac cgacatataa tccctgcgga
    66481 cactctcacc agtaacaata acaatcgtgt catataatgg tgctcccggc aggattttcc
    66541 agctgtcagc accgtgccga ctcagttgtt cataacgctg catttcacgc aatgtgtcag
    66601 ttgtccccac aactgttcct ttaaccatcc gtaacggcca gctgtttaca gagcataata
    66661 cgaataacaa cagagccatc gcgttacgtt gaccacggtg gtgtgtccgc cagaaaataa
    66721 ccatgaacac cagaatcgcg gcactgacca gaaaatgata aacaggaatc atcccggtaa
    66781 actccgcagc ctcatccgcc gtggtctgca acaacgcgac aataaaactg ttgttgattt
    66841 ttccgtacgt cataccgaca ggtgcataca gtgcacaaca gaacagaaat aacagagctg
    66901 taatggatgt aagggtattt ctgtgtgcaa gaatcagaag gagaaacagc agcaacacat
    66961 tcccggtggc attcttctca gtgtatccgc atgcggcagt ggttattaca cacatgcccg
    67021 ggaagaataa aaacaataaa atccgggata tattgtccgt ataaaacagc tttctgatat
    67081 tcatcggagt atatcgacaa cattattgtg aagagaataa aaatcagaag tctcctgtga
    67141 aacagataac agacaaccct gcagtataat tactgcaggg agtcttcgtt taattacaga
    67201 agatgggtaa ttattatctt tcaggagcag ttttgtcaga agttataagt cacaccaagc
    67261 atgatgtcat gacttttaac atcaacttct gatttatatt tatcgcccca ctcgtccttg
    67321 taactcacac tgctgtcacc tgcatcaaga tagcgatagc tgaggtccag agcgatatcc
    67381 ggggttacgt catagcggac acccgcgcca aagctccatg cgaagttgtc agcagagcct
    67441 gaacgtgaca acgattcgcg accactgctt ccgtacccat aatcccaggt actgataccg
    67501 gttgttttct ggtgaattct ggcgtagcca atccctgcag atacccatgg tgtgaatgca
    67561 ctgtcattcc ggaagtcata gtacgcattc agcatcagtg tgttgactga cacctcattc
    67621 ttcaggtcat cacgccagta accgcctgac cagctgtctt tatctacgtt atacttcgaa
    67681 tcagcttttc cacgagcgta aaactccagt tccgtacgaa ccggaatact gaactgcggg
    67741 taaaaatcat aaccggccgc gataccgcca ctgaataccg tatcatggcc atcaccgcct
    67801 ttatattttg atgtttcctc tccatcaccc gacaggaaac gctggtctgc aagtgacata
    67861 acagaagcac ctgctttacc ggtcacataa aagcctgttt tgctctcatc agccagagcc
    67921 tgggtcgaaa acatgcctgc catggcaagc gctgaaaccg caataacctt attcatttca
    67981 atcatctccg ctatcacttt ccccgaacga taaatggggt tgctcattct aaaaccatgc
    68041 aaaagatagg gtaaaaggaa tgttttcgat cgaatcgatc gataaaatcg atcgtgcccg
    68101 ataaagtttt cttatcgtac ccataaaaat ggtaagggct ggtttaagag gtaatcgcag
    68161 cggcatggaa gtattaagac caaaacagca cgagataaag cggctgaacg tcagatgagc
    68221 cacatggaac gtaattcatt aagggcggct tatatccata aaacagaaca cctggaatag
    68281 cgtcggttga tgctacagtg gtggggggat tttctggata caaactcgaa agaaaatacc
    68341 agcccctttg agtata
//
LOCUS       DADXDL010000013        66253 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.013, whole genome shotgun sequence.
ACCESSION   DADXDL010000013 DADXDL010000000
VERSION     DADXDL010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 66253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 66253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..66253
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.013"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            20..736
                     /locus_tag="IRB70_001122"
     CDS             20..736
                     /locus_tag="IRB70_001122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBC0631066.1"
                     /translation="MVAKINRLLRLGPVLLLCTSFFAQSNMTVYPMSVSINSQGEGSV
                     RVISKTNEVQYIKATVFRIDNPSTPQEKEIEVTSGDANQLVIMPPKFALPGGSSKTVR
                     FVAMEPEQKEKNYRVKFEAVPSIDDATDNKKDLSMQLTVNLIWGIVVSVPPQQPVAKL
                     DINADKKLINNGNQRLKILTIAYCKNSGSAECRTQTVNKNIFPGQERVLESISGYDKI
                     VVKYNNWITKDNGEFELAVH"
     gene            766..1266
                     /locus_tag="IRB70_001123"
     CDS             766..1266
                     /locus_tag="IRB70_001123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000755097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0631067.1"
                     /translation="MKKVFAKSLMVAAMFSVAGSALAVQKDITVTANVDAALDMTQTD
                     NTALPKAVEMQYLPGQGLQSYQLMTKIWSNDTTKDVKMQLVSPAQLVQSLDASKIVPL
                     TVTWGGEEIKADAATTFTATKIFASDALTNGSLAKPLMFSQATKGVLETGIYRGVVSI
                     YLSQAL"
     gene            1357..4041
                     /locus_tag="IRB70_001124"
     CDS             1357..4041
                     /locus_tag="IRB70_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TcfC E-set like domain-containing protein"
                     /protein_id="HBC0631068.1"
                     /translation="MDKKLLALLILASLSPAKATLTKIPAGFEVIAQGQQEYIEVYFA
                     GKSLGKYYAMVNLDTVTFLDSSSLYSKLELSTDDQKIAHTVKEKLSQPLARHGELACG
                     FVRTDSGCGFLNTETVEIIYNDEESSATLFLNPQWSSAFNSKSLYLNPDKNTVNAFIH
                     QQDINVLVQDDYQSLSIQGNGALGITENSYIGAHWNFDGYDADDVSDNNVDVSDLYYR
                     YDFLRRYYVQAGRMDNRTLFNAQGGNFTFNFLPLGAIDGMRIGSTLSYLNQTQSQQGT
                     PVMILLSRNSRVDAYRNEQLLGSFYLNSGSQFIDTSSFPPGSYSVALKVYENNQLTRT
                     ELVPFTKTGGLTDGNAQWFLQAGKTTSQVSDDESSAYQLGVRLPLHPQYELYAGLANA
                     DDVSAFELGNNWTADLGGAGNLAISASVFRNDDGGKGDMQQANWSHPGWPTLGFYRTN
                     SDGDACTTDNRESYNALSCYESISATVSQNFVGWNMMLGYTRTQNNTDDSLRWDKQQS
                     FENNYLRQTSAQSISETVQLSASRAFVMRDWILSTSLGVFHRNDNGGGSDDNGLYLSF
                     SLSDTPTMDSNNNSHSTNVSTDYRYSDQDGDQTSWQLSHTFYNDSFSHKELGVTVGGL
                     NTDTINSAVNGRWDGQYGNVYATVSDSYDRQNHDHLSAFTGTYSSTLAVSRYGINLGA
                     SGSDDLLGAVLVDVKGFSEQDEQSQGLQLEARVAGSRTLQLGQSDSVLFPYPGFQSGF
                     VEVNDSNQGNQQGTTNIINGAGNRELMLLPGKLRYREVSASFNYNYIGRLLLPASVEK
                     FPLVGLNSAMLLVAEDGGFTLEISSGEKELYLLSGQQFLKCPLNVLKKRASIRYSGDV
                     NCSVVSYSQLPESIQVQAQLKQPKLRGNVQTAQREVAP"
     gene            4038..5132
                     /locus_tag="IRB70_001125"
     CDS             4038..5132
                     /locus_tag="IRB70_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein CblD"
                     /protein_id="HBC0631069.1"
                     /translation="MRNRLIAVILCLFGMVAGGHATPNVTAEITYDLAAGRADYYFWN
                     REDPPAVSYNTTWSSYKCDFPDVQQTCTASGNLSTVKIYLTEKRSGMRWPVKLKGYVD
                     AEVWNPGGVCNGWSTQIALANGTGYQCKSASDGYIQHLASAKPMTLYLEQSEMKNLPI
                     GGVWEGSVKLQFTNPSTDYRADITLNVLDPNHIDVFFPEFAHATPRVQLDLHPTGSVN
                     GNNYAQDLTMLDMCLYDGFNGNGLSYEILLKDEGRTAAGRSNGEFSIYRQGASSTDEG
                     ERIDYRVKMYDPESGGQIDVRNNESMVWTNINLKRVRPVVLPGIRYAVMCVPTPLTLV
                     VDKFNVTAKQAGYYMGKLSVIFTPSLPTIN"
     gene            complement(5208..6506)
                     /gene="exuT"
                     /locus_tag="IRB70_001126"
     CDS             complement(5208..6506)
                     /gene="exuT"
                     /locus_tag="IRB70_001126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708898.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexuronate transporter ExuT"
                     /protein_id="HBC0631070.1"
                     /translation="MRKIKGLRWYMIALVTLGTVLGYLTRNTVAAAAPTLMEELNIST
                     QQYSYIIAAYSAAYTVMQPVAGYVLDVLGTKIGYAMFAVLWAVFCGATALAGSWGGLA
                     VARGAVGAAEAAMIPAGLKASSEWFPAKERSIAVGYFNVGSSIGAMIAPPLVVWAIVM
                     HSWQMAFIISGALSFIWAMAWLIFYKHPRDQKHLTDEERDYIINGQEAQHQVDTAKKM
                     SVGQILRNRQFWGIALPRFLAEPAWGTFNAWIPLFMFKVYGFNLKEIAMFAWMPMLFA
                     DLGCILGGYLPPLFQRWFGVNLIVSRKMVVTLGAVLMIGPGMIGLFTNPYVAIMLLCI
                     GGFAHQALSGALITLSSDVFGRNEVATANGLTGMSAWLASTLFALVVGALADTIGFSP
                     LFAVLAVFDLLGALVIWTVLQNKPAIEVAQESHNDPAPQH"
     gene            6989..8401
                     /gene="uxaC"
                     /locus_tag="IRB70_001127"
     CDS             6989..8401
                     /gene="uxaC"
                     /locus_tag="IRB70_001127"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019077755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBC0631071.1"
                     /translation="MTPFMTEDFLLDTEFARRLYHDYAKDQPIFDYHCHLPPQQIAED
                     YRFKNLYDIWLKGDHYKWRAMRTNGVAERLCTGDASDREKFDAWAATVPHTIGNPLYH
                     WTHLELRRPFGITGKLLSPSTADEIWNECNELLAQDNFSARGIMQQMNVKMVGTTDDP
                     IDSLEHHAEIAKDGSFTIKVLPSWRPDKAFNIEQATFNDYMAKLGEVSDTDIRRFADL
                     QTALTKRLDHFAAHGCKVSDHALDVVMFAEANEAELDSILARRLAGETLSEHEVAQFK
                     TAVLVFLGAEYARRGWVQQYHIGALRNNNLRQFKLLGPDVGFDSINDRPMAEELSKLL
                     SKQNEENLLPKTILYCLNPRDNEVLGTMIGNFQGEGMPGKMQFGSGWWFNDQKDGMER
                     QMTQLAQLGLLSRFVGMLTDSRSFLSYTRHEYFRRILCQMIGRWVEAGEAPADINLLG
                     EMVKNICFNNARDYFAIELN"
     gene            8416..9903
                     /gene="uxaA"
                     /locus_tag="IRB70_001128"
     CDS             8416..9903
                     /gene="uxaA"
                     /locus_tag="IRB70_001128"
                     /EC_number="4.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBC0631072.1"
                     /translation="MQYIKIHALDNVAVALADLAEGTEVSVDNQTVTLRQDVARGHKF
                     ALTDIAKGANVIKYGLPIGYALADIAAGEHVHAHNTRTNLSDLDQYRYQPDFQDLPAQ
                     AADREVQIYRRANGDVGVRNELWILPTVGCVNGIARQIQNRFLKETNNAEGTDGVFLF
                     SHTYGCSQLGDDHINTRTMLQNMVRHPNAGAVLVIGLGCENNQVAAFRETLGDIDPER
                     VHFMICQQQDDEIEAGIAHLHQLYNVMRNDKREPGKLSELKFGLECGGSDGLSGITAN
                     PMLGRFSDYVIANGGTTVLTEVPEMFGAEQLLMDHCRDEATFEKLVTMVNDFKQYFIA
                     HDQPIYENPSPGNKAGGITTLEDKSLGCTQKAGSSVVVDVLRYGERLKTPGLNLLSAP
                     GNDAVATSALAGAGCHMVLFSTGRGTPYGGFVPTVKIATNSELAAKKKHWIDFDAGQL
                     IHGKAMPQLLEEFIDTIVEFANGKQTCNERNDFRELAIFKSGVTL"
     gene            9986..10537
                     /locus_tag="IRB70_001129"
     CDS             9986..10537
                     /locus_tag="IRB70_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgjV family protein"
                     /protein_id="HBC0631073.1"
                     /translation="MTAYWLAQGVGVIAFLIGITTFFNRDERRFKKQLSVYSAVIGVH
                     FFLLGTYPAGASAILNAIRTLITLRTRSLWVMAIFIVLTGGIGLAKFHHPVELLPVIG
                     TIVSTWALFRCKGLTMRCVMWFSTCCWVIHNFWAGSIGGTMIEGSFLLMNGLNIIRFW
                     RMQKRGIDPFKVEKTPSAVDERG"
     gene            complement(10541..11785)
                     /gene="sstT"
                     /locus_tag="IRB70_001130"
     CDS             complement(10541..11785)
                     /gene="sstT"
                     /locus_tag="IRB70_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBC0631074.1"
                     /translation="MTTQRSPGLFRRLAHGSLVKQILVGLVLGILLAWISKPAAEAVG
                     LLGTLFVGALKAVAPILVLMLVMASIANHQHGQKTNIRPILFLYLLGTFSAALAAVIF
                     SFAFPSTLHLSSSAGDISPPSGIVEVMRGLVMSMVSNPIDALLKGNYIGILVWAIGLG
                     FALRHGNETTKNLVNDMSNAVTFMVKLVIRFAPIGIFGLVSSTLATTGFSTLWGYAQL
                     LVVLVGCMLLVALVVNPLLVWWKIRRNPFPLVLLCLRESGVYAFFTRSSAANIPVNMA
                     LCEKLNLDRDTYSVSIPLGATINMAGAAITITVLTLAAVNTLGIPVDLPTALLLSVVA
                     SLCACGASGVAGGSLLLIPLACNMFGISNDIAMQVVAVGFIIGVLQDSCETALNSSTD
                     VLFTAAACQAEDDRLANSALRN"
     gene            complement(12109..13074)
                     /gene="alx"
                     /locus_tag="IRB70_001131"
     CDS             complement(12109..13074)
                     /gene="alx"
                     /locus_tag="IRB70_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001098826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family membrane protein Alx"
                     /protein_id="HBC0631075.1"
                     /translation="MNTVGTPLLWGGFAVVVTIMLAIDLLLQGRRGAHAMTMKQAAAW
                     SLVWVTLSLLFNAAFWWYLVQTEGRAVADPQALAFLTGYLIEKSLAVDNVFVWLMLFS
                     YFSVPAALQRRVLVYGVLGAIVLRTIMIFTGSWLISQFDWILYIFGAFLLFTGVKMAL
                     AHEDESGIGDKPLVRWLRGHLRMTDTIDNEHFFVRKNGLLYATPLMLVLILVELSDVI
                     FAVDSIPAIFAVTTDPFIVLTSNLFAILGLRAMYFLLAGVAERFSMLKYGLAVILVFI
                     GIKMLIVDFYHIPIAVSLGVVFGILVMTFIINAWVNYRHDKQRVE"
     gene            complement(13357..14343)
                     /locus_tag="IRB70_001132"
     CDS             complement(13357..14343)
                     /locus_tag="IRB70_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417558.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBC0631076.1"
                     /translation="MIRFAVIGTNWITRQFVEAAHESGKYKLTAVYSRSLEQAQHFAN
                     DFSVEHLFTSLEAMAESDAIDAVYIASPNSLHFSQTQLFLSHKIHVICEKPLASNQAE
                     VDAAIACARENQVVLFEAFKTAYLPNFHLLRQALPKVGKLRKVFFNYCQYSSRYQRYL
                     DGENPNTFNPAFSNGSIMDIGFYCLASAVALFGEPKSVQATASLLASGVDAHGVVVMD
                     YGDFSVTLQHSKVSDSVLASEIQGEAGSLVIEKLSECQKVCFVPRGSQMQDLTQPQHI
                     NTMLYEAELFATLVDEHLVNHPGLAVSRITAKLLTEIRRQTGVIFPADNVKL"
     gene            complement(14422..15114)
                     /locus_tag="IRB70_001133"
     CDS             complement(14422..15114)
                     /locus_tag="IRB70_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vancomycin high temperature exclusion protein"
                     /protein_id="HBC0631077.1"
                     /translation="MLRAFARLLLRICFSRRTLKIGCLLLLIAGATIFIADRVMVNAS
                     KQLTWSDVNAVPARNVGLLLGARPGNRYFTRRIDSAAELYHAGKVKWLLVSGDNGRKN
                     YDEASGMQQALIAKGVPAKAIFCDYAGFSTLDSVVRANKVFSENHITIISQEFHNQRA
                     IWLAKQYGIDAIGFNAPDLNMKHGLYTQLREKLARVSAVIDAKILHRQPKYLGPLVMI
                     GPFSEHGCPAKE"
     gene            complement(15191..15694)
                     /locus_tag="IRB70_001134"
     CDS             complement(15191..15694)
                     /locus_tag="IRB70_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M48 family metallopeptidase"
                     /protein_id="HBC0631078.1"
                     /translation="MSNLTYLQGYPEQLLSQVRTLINEQRLGDVLAKRYPGTHDYATD
                     KALWQYTQDLKNQFLRNAPPINKVMYDNKIHVLKNALGLHTAVSRVQGGKLKAKAEIR
                     VATVFRNAPEPFLRMIVVHELAHLKEKEHNKAFYQLCCHMEPQYHQLEFDTRLWLTQL
                     SLGQDKI"
     gene            15779..16915
                     /gene="rlmG"
                     /locus_tag="IRB70_001135"
     CDS             15779..16915
                     /gene="rlmG"
                     /locus_tag="IRB70_001135"
                     /EC_number="2.1.1.174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(1835)-N(2))-methyltransferase
                     RlmG"
                     /protein_id="HBC0631079.1"
                     /translation="MSHLDNGFRSLTLQRFPATDDVNPLQAWEAADEYLLQQLDDTEI
                     RGLVLILNDAFGALSCALAEHKPYSIGDSYISELATRENLRLNGIDESSVKFLDSTAD
                     YPQQPGVVLIKVPKTLALLEQQLRALRKVVTPDTRIIAGAKARDIHTSTLELFEKVLG
                     PTTTTLAWKKARLINCTFNEPPLADAPQTVSWKLEGTDWTIHNHANVFSRTGLDIGAR
                     FFMQHLPENLEGEIVDLGCGNGVIGLTLLDKNPQAKVVFVDESPMAVASSRLNVETNM
                     PEALDRCEFMINNALSGVEPFRFNAVLCNPPFHQQHALTDNVAWEMFHHARRCLKING
                     ELYIVANRHLDYFHKLKKIFGNCTTIATNNKFVVLKAVKLGRRR"
     gene            17200..17513
                     /gene="higB"
                     /locus_tag="IRB70_001136"
                     /pseudo
     CDS             17200..17513
                     /gene="higB"
                     /locus_tag="IRB70_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311992.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin HigB"
     gene            17510..17926
                     /gene="higA"
                     /locus_tag="IRB70_001137"
     CDS             17510..17926
                     /gene="higA"
                     /locus_tag="IRB70_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HigA"
                     /protein_id="HBC0631080.1"
                     /translation="MIAIADILQAGEKLTAVAPFLAGIQNEEQYTQALELVDHLLLND
                     PENPLLDLVCAKITAWEESAPEFVEFNAMAQAMPGGIAVIRTLMDQYGLTLSDLPEIG
                     SKSMVSRVLSGKRKLTLEHAKKLATRFGISPALFID"
     gene            complement(17971..19989)
                     /gene="fadH"
                     /locus_tag="IRB70_001138"
     CDS             complement(17971..19989)
                     /gene="fadH"
                     /locus_tag="IRB70_001138"
                     /EC_number="1.3.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 2,4-dienoyl-CoA reductase"
                     /protein_id="HBC0631081.1"
                     /translation="MSYPSLFAPLDLGFTTLKNRVLMGSMHTGLEEYPDAAERLAAFY
                     AERARHGVALIVSGGIAPDLTGVGMEGGAMLNDANQIPHHRTITEAVHQEGGKIALQI
                     LHTGRYSYQPHLVAPSALQAPINRFVPHELTHEEILQLIDDFAHCAQLAREAGYDGVE
                     VMGSEGYLINEFLTLRTNQRSDQWGGDYRNRMRFAVEVVGAVRERVGNDFIIIYRLSM
                     LDLVEGGGTFAETVELAQAIEAAGATIINTGIGWHEARIPTIATPVPRGAFSWVTRKL
                     KGHVSLPLVTTNRINDPQVADDILSRGDADMVSMARPFLADAELLSKAQSGRADEINT
                     CIGCNQACLDQIFVGKVTSCLVNPRACHETKMPILPAVQKKNLAVVGAGPAGLAFAIN
                     AAARGHQVTLFDAHSEIGGQFNIAKQIPGKEEFYETLRYYRRMIEVTGVTLKLNHTVT
                     ADQLQAFDETILASGIVPRVPPIDGIDHPKVLSYLDVLRDKAPVGNKVAIIGCGGIGF
                     DTAMYLSQPGESTSQNIAGFCNEWGIDSSLQQAGGLSPQGMQIPRSPRQIVMLQRKAS
                     KPGQGLGKTTGWIHRTTLLSRGVKMIPGVSYQKIDDDGLHVVINGETQVLAVDNVVIC
                     AGQEPNRALAQPLIDSGKTVHLIGGCDVAMELDARRAIAQGTRLALEI"
     gene            complement(20215..22566)
                     /gene="ygjK"
                     /locus_tag="IRB70_001139"
     CDS             complement(20215..22566)
                     /gene="ygjK"
                     /locus_tag="IRB70_001139"
                     /EC_number="3.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBC0631082.1"
                     /translation="MKIKTILTPVTCALLISFSAHAANADNYKNVINRTGAPQYMKDY
                     DYDDHQRFNPFFDLGAWHGHLLPDGPNTMGGFPGVALLTEEYINFMASNFDRLTVWQD
                     GKKVDFTLEAYSIPGALVQKLISKDVQVEMILRFATPRTSLLETKITSDKPLDLVWDG
                     ELLEKLEAKEGKPLSDKTIAGEYPDYQRKISATRDGLKVTFGKVRATWDLLTSGESEY
                     QVHKSLPVQTEINGNRFTSKAHINGSTTLYTTYSHLLTAQEVSKEQMQIRDILARPAF
                     YLTASQQRWEEYLKKGLTNPDATPEQTRVAVKAIETLNGNWRSPGGAVKYNTVTPSVT
                     GRWFSGNQTWPWDTWKQAFAMAHFNPDIAKENIRAVFSWQIQPGDAVRPQDVGFVPDL
                     IAWNLSPERGGDGGNWNERNTKPSLAAWSVMEVYNVTQDKAWLAEMYPKLVAYHDWWL
                     RNRDHNGNGVPEYGATRDKAHNTESGEMLFTVKKGDKEETQSGLNNYARVVEKGQYDS
                     LEIPAQVAASWESGRDDAAVFGFIDKEQLDKYVANGGKRSDWTVKFAENRSKDGTLLG
                     YSLLQESVDQASYMYSDNHYLAEMATILGKPEEAKRYRQLAQQLADYINTCMFDPTTQ
                     FYYDVRIEDKPLANGCAGKPIIERGKGPEGWSPLFNGAATQANADAVVKVMLDPKEFD
                     TFVPLGTAALTNPAFGADIYWRGRVWVDQFWFGLKGMERYGYRDDALKLADTFFRHAK
                     GLTADGPIQENYNPLTGAQQGAPNFSWSAAHLYMLYNDFFRKQ"
     gene            complement(22583..23653)
                     /gene="ygjJ"
                     /locus_tag="IRB70_001140"
     CDS             complement(22583..23653)
                     /gene="ygjJ"
                     /locus_tag="IRB70_001140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgjJ"
                     /protein_id="HBC0631083.1"
                     /translation="MKLITAPCRALLALPFCYAFSAAADEARPAEHDDSKTPAMTSTS
                     SPSFRFYGELGVGGYMDLEGENKHKYSDGTYIEGGLEMKYGSWFGLIYGEGWTVQADH
                     DGNAWVPDHSWGGFEGGINRFYGGYRTNDGTEIMLSLRQDSSLDDLQWWGDFTPDLGY
                     VIPNTRDIMTALKVQNLSGNFRYSVTATPTGHHDESKAWLHFGKYDRYDDKYTYPAMM
                     NGYIQYDLTEGITWMNGLEITDGTGQLYLTGLLTPNFAARAWHHTGRADGLDVPGSES
                     GMMVSAMYEALKGVYLSTAYTYAKHRPDHADDETTSFMQFGIWYEYGGGRFATAFDSR
                     FYMKNASHDPSDQLFLMQYFYW"
     gene            complement(23787..25220)
                     /locus_tag="IRB70_001141"
     CDS             complement(23787..25220)
                     /locus_tag="IRB70_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBC0631084.1"
                     /translation="MSDTKRNTIGKFGLLSLTFAAVYSFNNVINNNIELGLASAPMFF
                     LATIFYFIPFCLIIAEFVSLNKNSEAGVYAWVKSSLGGRWAFITAYTYWFVNLFFFTS
                     LLPRVIAYASYAFLGYEYIMTPVATTIISMVLFAFSTWVSTNGAKMLGPITSVTSTLM
                     LLLTLSYILLAGTALVGGVQPADPITVDAMIPNFNWAFLGVTTWIFMAAGGAESVAVY
                     VNDVKGGSKSFVKVIILAGIFIGVLYSVSSVLINVFVSSKELKFTGGSVQVFHGMAAY
                     FGLPEALMNRFVGLVSFTAMFGSLLMWTATPVKIFFSEIPEGIFGKKTVELNENGVPA
                     RAAWIQFLIVIPLMIIPMLGSNTVQDLMNTIINMTAAASMLPPLFIMLAYLNLRAKLD
                     HLPRDFRMGSRRTGIIVVSMLIAIFAVGFVASTFPTGANILTIIFYNVGGIVIFLGFA
                     WWKYSKYIKGLTAEERHIEATPASNVD"
     gene            complement(25283..25732)
                     /locus_tag="IRB70_001142"
     CDS             complement(25283..25732)
                     /locus_tag="IRB70_001142"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit beta"
                     /protein_id="HBC0631085.1"
                     /translation="MRIIDNLEQFRQIYASGKKWQRCVEAIENIDNIQPGVAHSIGDS
                     LTYRVETDSATDALFTGHRRYFEVHYYLQGQQKIEYAPKETLQVVEYYRDETDREYLK
                     GCGETVEVHEGQIVIYDIHEAYRFICNNAVKKVVLKVTIEDGYFHNK"
     gene            complement(25729..28821)
                     /gene="ebgA"
                     /locus_tag="IRB70_001143"
     CDS             complement(25729..28821)
                     /gene="ebgA"
                     /locus_tag="IRB70_001143"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311985.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase subunit alpha"
                     /protein_id="HBC0631086.1"
                     /translation="MNRWENIQLTHENRLAPRAYFFSYDSVAQARTFARETSSLFLPL
                     SGQWNFHFFDHPLQVPEAFTSELMADWGHITVPAMWQMEGHGKLQYTDEGFPFPIDVP
                     FVPSDNPTGAYQRIFTLSDGWQGKQTLIKFDGVETYFEVYVNGQYVGFSKGSRLTAEF
                     DISAMVKTGDNLLCVRVMQWADSTYVEDQDMWWSAGIFRDVYLIGKQLTHINDFTVRT
                     DFDEAYCDATLSCEVVLENLAASPVVTTLEYTLFDGELVVHSSAIDHLAIEKLTSASF
                     AFTVEQPQQWSAESPYLYHLVMTLKDADGNVLEVVPQRVGFRDIKVRDGLFWINNRYV
                     MLHGVNRHDNDHRKGRAVGMDRVEKDLQLMKQHNINSVRTAHYPNDPRFYELCDIYGL
                     FVMAETDVESHGFANVGDISRITDDPQWEKVYVERIVRHIHAQKNHPSIIIWSLGNES
                     GYGCNIRAMYHAAKALDDTRLVHYEEDRDAEVVDIISTMYTRVPLMNEFGEYPHPKPR
                     IICEYAHAMGNGPGGLTEYQNVFYKHDCIQGHYVWEWCDHGIQAQDDNGNVWYKFGGD
                     YGDYPNNYNFCLDGLIYSDQTPGPGLKEYKQVIAPVKIHALDLTRGELKVENKLWFTT
                     LDDYTLHAEVRAEGETLATQQIKLRDVAPNSEAPLQITLPQLDAREAFLNITVTKDSR
                     TRYSEAGHSIATYQFPLKENTAQPVPFAPNNARPLTLEDDRLSCTVRGYNFAITFSKT
                     SGKPTSWQVNGESLLTREPKINFFKPMIDNHKQEYEGLWQPNHLQIMQEHLRDFAVEQ
                     SDGEVLIISRTVIAPPVFDFGMRCTYIWRIAADGQVNVALSGERYGDYPHIIPCIGFT
                     MGINGEYDQVAYYGRGPGENYADSQQANIIDIWRSTVDAIFENYPFPQNNGNRQHVRW
                     TALTNRHGNGLLVVPQRPINFSAWRYTQENIHAAQHCNELQRSDDITLNLDHQLLGLG
                     SNSWGSEVLDSWRVWFRDFSYGFTLLPVSGGEATAQSLASYEFGAGFFSTNLHSENKQ
                     "
     gene            complement(29005..29988)
                     /gene="ebgR"
                     /locus_tag="IRB70_001144"
     CDS             complement(29005..29988)
                     /gene="ebgR"
                     /locus_tag="IRB70_001144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator EbgR"
                     /protein_id="HBC0631087.1"
                     /translation="MATLKDIAIEAGVSLATVSRVLNDDPTLNVKEETKHRILEIAEK
                     LEYKTSSARKLQTGAVNQHHILAIYSYQQELEINDPYYLAIRHGIETQCEKLAIELTN
                     CYEHNGLPDIKNVTGILIVGKPTPALRAAACALTDNICFIDFHEPGSGYDAVDIDLAR
                     ISKEIIDFYIDQGVNRIGFIGGEDLPGKADIREVAFVEYGRLKHVVREEDIWRGGFSS
                     SSGYELAKQMLAREDYPKALFVASDSIAIGVLRAIHERGLNIPQDISLISVNDIPTAR
                     FTFPPLSTVRIHSEMMGSQGVNLVYEKARDGRALPLLIFVPSKLKLRGTTR"
     gene            30207..30539
                     /locus_tag="IRB70_001145"
     CDS             30207..30539
                     /locus_tag="IRB70_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-binding protein"
                     /protein_id="HBC0631088.1"
                     /translation="METVAYADFARLEMRVGKIVEVKRHENADKLYIVQVDVGEKTLQ
                     TVTSLVPYYSEEELMGKTVVVLCNLQKAKMRGETSECMLLCAETDDGSESVLLTPERM
                     MPAGVRIV"
     gene            complement(30581..31960)
                     /gene="ygjG"
                     /locus_tag="IRB70_001146"
     CDS             complement(30581..31960)
                     /gene="ygjG"
                     /locus_tag="IRB70_001146"
                     /EC_number="2.6.1.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417544.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine aminotransferase"
                     /protein_id="HBC0631089.1"
                     /translation="MNRLPSSASALACSAHALNLIEKRTLDHEEMKALNREVIEYFKE
                     HVNPGFLEYRKSVTAGGDYGAVEWQAGGLNTLVDTQGQEFIDCLGGFGIFNVGHRNPV
                     VVSAVQNQLAKQPLHSQELLDPLRAILAKTLAALTPGKLKYSFFCNSGTESVEAALKL
                     AKAYQSPRGKFTFIATSGAFHGKSLGALSATAKSTFRKPFMPLLPGFRHVPFGNIEAM
                     RTALSECKKTGDDVAAVILEPIQGEGGVILPPPGYLTAVRKLCDEFGALMILDEVQTG
                     MGRTGKMFACEHENVQPDILCLAKALGGGVMPIGATIATEEVFSVLFDNPFLHTTTFG
                     GNPLACAAALATINVLLEQNLPAQAEQKGDMLLDGFRQLAREYPDLVQEARGKGMLMA
                     IEFVDNEIGYNFASEMFRQRVLVAGTLNNAKTIRIEPPLTLTIEQCEQVIKAARKALA
                     AMRVSVEEA"
     gene            32378..33898
                     /gene="aer"
                     /locus_tag="IRB70_001147"
     CDS             32378..33898
                     /gene="aer"
                     /locus_tag="IRB70_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerotaxis sensor receptor Aer"
                     /protein_id="HBC0631090.1"
                     /translation="MSSHPYVTQQNTPLADDTTLMSTTDLQSYITHANDTFVQVSGYT
                     LQELQGQPHNMVRHPDMPKAAFADMWFTLKKGEPWSGIVKNRRKNGDHYWVRANAVPM
                     VREGKISGYMSIRTRATDEEIAAVEPLYKALNAGRTSKRIHKGLVVRKGWLGKLPSLP
                     LRWRARGVMTLMFILLAAMLWFVAAPVVTYILCALVVLLASACFEWQIVRPIENVARQ
                     ALKVATGERNSVEHLNRSDELGLTLRAVGQLGLMCRWLINDVSSQVSSVRNGSETLAK
                     GTDELNEHTQQTVDNVQQTVATMNQMAASVKQNSATASAADKLSITASNAAVQGGEAM
                     TTVIKTMDDIADSTQRIGTITSLINDIAFQTNILALNAAVEAARAGEQGKGFAVVAGE
                     VRHLASRSANAANDIRKLIDASADKVQSGSQQVHAAGRTMEDIVAQVKNVTQLIAQIS
                     HSTLEQADGLSSLTRAVDELNLITQKNAELVEESAQVSAMVKHRASRLEDAVTVLH"
     gene            complement(33994..34617)
                     /gene="nfeR"
                     /locus_tag="IRB70_001148"
                     /gene_synonym="yqjI"
     CDS             complement(33994..34617)
                     /gene="nfeR"
                     /locus_tag="IRB70_001148"
                     /gene_synonym="yqjI"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NfeR"
                     /protein_id="HBC0631091.1"
                     /translation="MSHHHEGCCKHEGQPRHEGCCKGEKSEHEHCGHGHQHEHGQCCG
                     GRHGRGGGRRQRFFGHGELRLVILDILSRDDSHGYELIKAIENLTQGNYTPSPGVIYP
                     TLDFLQEQSLITIREEEGGKKQIALTEQGSQWLEENREQVEMIEERIKARCVGAALRQ
                     NPQMKRALDNFKAVLDLRVNQSDITDAQIKKIIAVIDRAAFDITQLD"
     gene            34905..35669
                     /gene="nfeF"
                     /locus_tag="IRB70_001149"
     CDS             34905..35669
                     /gene="nfeF"
                     /locus_tag="IRB70_001149"
                     /EC_number="1.16.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent ferric chelate reductase"
                     /protein_id="HBC0631092.1"
                     /translation="MNNSPRYPQRVRNDLRFRELTVLRVERISVGFQRIVLGGEALDG
                     FTSRGFDDHSKLFFPQSDAHFVPPTVTEEGIVWPEGPRPPSRDYTPLYDELRHELAID
                     FFIHDDGVASGWAMQAQPGDKLTVAGPRGSLVVPEDYAYQVYVCDESGMPALRRRLET
                     LSKLAVKPQVSALVSVRDNACQDYLAHLDGFNIEWLAHDEQAVDARLAQMQIPADDYF
                     IWITGEGKVVKNLSRRFEAEQYDPQRVRAAAYWHAK"
     gene            complement(35723..35798)
                     /locus_tag="IRB70_001150"
     tRNA            complement(35723..35798)
                     /locus_tag="IRB70_001150"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(35763..35765),aa:Ile,seq:cat)
     gene            35923..36429
                     /gene="mug"
                     /locus_tag="IRB70_001151"
     CDS             35923..36429
                     /gene="mug"
                     /locus_tag="IRB70_001151"
                     /EC_number="3.2.2.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="G/U mismatch-specific DNA glycosylase"
                     /protein_id="HBC0631093.1"
                     /translation="MVEDILAPGLRVVFCGINPGLSSAGTGFPFAHPANRFWKVIYQA
                     GFTDRQLKPQEAQHLLDYRCGVTKLVDRPTVQANEVSKQELHAGGRKLIEKIEDYQPQ
                     ALAILGKQAYEQGFSQRGAQWGKQTLTIGSTQIWVLPNPSGLSRVSLEKLVEAYRELD
                     QALVVRGR"
     gene            complement(36508..38349)
                     /gene="rpoD"
                     /locus_tag="IRB70_001152"
     CDS             complement(36508..38349)
                     /gene="rpoD"
                     /locus_tag="IRB70_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBC0631094.1"
                     /translation="MEQNPQSQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDI
                     IQMINDMGIQVMEEAPDADDLMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYM
                     REMGTVELLTREGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSD
                     LITGFVDPNAEEDLAPTATHVGSELSQEDLDDDEDEDEEDGDDDSADDDNSIDPELAR
                     EKFAELRAQYVVTRDTIKAKGRSHAAAQEEILKLSEVFKQFRLVPKQFDYLVNSMRVM
                     MDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTWFNAAIAMNKPWSEKLHDVS
                     EEVHRALQKLQQIEEETGLTIEQVKDINRRMSIGEAKARRAKKEMVEANLRLVISIAK
                     KYTNRGLQFLDLIQEGNIGLMKAVDKFEYRRGYKFSTYATWWIRQAITRSIADQARTI
                     RIPVHMIETINKLNRISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISME
                     TPIGDDEDSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGID
                     MNTDHTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD"
     gene            complement(38544..40289)
                     /gene="dnaG"
                     /locus_tag="IRB70_001153"
     CDS             complement(38544..40289)
                     /gene="dnaG"
                     /locus_tag="IRB70_001153"
                     /EC_number="2.7.7.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBC0631095.1"
                     /translation="MAGRIPRVFINDLLARTDIVDLIDARVKLKKQGKNFHACCPFHN
                     EKTPSFTVNGEKQFYHCFGCGAHGNAIDFLMNYDKLEFVETVEELAAMHNLEVPFEAG
                     SGPSQIERHQRQTLYQLMDGLNTFYQQSLQQPVATSARQYLEKRGLSHEVIARFAIGF
                     APPGWDNVLKRFGGNPENRQSLIDAGMLVTNDQGRSYDRFRERVMFPIRDKRGRVIGF
                     GGRVLGNDTPKYLNSPETDIFHKGRQLYGLYEAQQDNAEPNRLLVVEGYMDVVALAQY
                     GINYAVASLGTSTTADHIQLLFRATNNVICCYDGDRAGRDAAWRALETALPYMTDGRQ
                     LRFMFLPDGEDPDTLVRKEGKEAFEARMEQAMPLSAFLFNSLMPQVDLSTPDGRARLS
                     TLALPLISQVPGETLRIYLRQELGNKLGILDDSQLERLMPKAAESGVSRPVPQLKRTT
                     MRILIGLLVQNPELATLVPPLENLDENKLPGLGLFRELVNTCLSQPGLTTGQLLEHYR
                     GTNNAATLEKLSMWDDIADKNIAEQTFTDSLNHMFDSLLELRQEELIARERTHGLSNE
                     ERLELWTLNQELAKK"
     gene            complement(40400..40615)
                     /gene="rpsU"
                     /locus_tag="IRB70_001154"
     CDS             complement(40400..40615)
                     /gene="rpsU"
                     /locus_tag="IRB70_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBC0631096.1"
                     /translation="MPVIKVRENEPFDVALRRFKRSCEKAGVLAEVRRREFYEKPTTE
                     RKRAKASAVKRHAKKLARENARRTRLY"
     gene            40853..41866
                     /gene="tsaD"
                     /locus_tag="IRB70_001155"
     CDS             40853..41866
                     /gene="tsaD"
                     /locus_tag="IRB70_001155"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001264383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBC0631097.1"
                     /translation="MRVLGIETSCDETGIAIYDDEKGLLANQLYSQVKLHADYGGVVP
                     ELASRDHVRKTVPLIQEALKESGLTAKDIDAVAYTAGPGLVGALLVGATVGRSLAFAW
                     DVPAIPVHHMEGHLLAPMLEDNPPEFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
                     AAGEAFDKTAKLLGLDYPGGPLLSKMAAQGTAGRFVFPRPMTDRPGLDFSFSGLKTFA
                     ANTIRDNGTDDQTRADIARAFEDAVVDTLMIKCKRALDQTGFKRLVMAGGVSANRTLR
                     AKLAEMMKKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGATADLGVSVRPRWPLAEL
                     PAA"
     gene            complement(41909..43372)
                     /gene="ttdT"
                     /locus_tag="IRB70_001156"
     CDS             complement(41909..43372)
                     /gene="ttdT"
                     /locus_tag="IRB70_001156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-tartrate/succinate antiporter"
                     /protein_id="HBC0631098.1"
                     /translation="MKPSTEWWRYLAPLAVIAIIALLPLPAGLESHTWLYFAVFTGVI
                     VGLILEPVPGAVVAMVGISIIAILSPWLLFSPEQLAQPGFKFTAKSLSWAVSGFSNSV
                     IWLIFAAFMFGTGYEKTGLGRRIALILVKKMGHRTLFLGYAVMFSELILAPVTPSNSA
                     RGAGIIFPIIRNLPPLYQSQPNDSSSRSIGSYIMWMGIVADCVTSAIFLTAMAPNLLL
                     IGLMKSASHATLSWGDWFLGMLPLSILLVLLVPWLAYVLYPPVLKSGDQVPRWAETEL
                     QAMGPLCSREKRMLGLMVGALVLWIFGGDYIDAAMVGYSVVALMLLLRIISWDDIVSN
                     KAAWNVFFWLASLITLATGLNNTGFISWFGKLLAGSLSGYSPTIVMVALIVVFYLLRY
                     FFASATAYTSALAPMMIAAALAMPEIPLPVFCLMVGAAIGLGSILTPYATGPSPIYYG
                     SGYLPTVDYWRLGAIFGLIFLVLLVITGLLWMPVVLL"
     gene            complement(43421..44026)
                     /gene="ttdB"
                     /locus_tag="IRB70_001157"
     CDS             complement(43421..44026)
                     /gene="ttdB"
                     /locus_tag="IRB70_001157"
                     /EC_number="4.2.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit beta"
                     /protein_id="HBC0631099.1"
                     /translation="MKKILTTPIKAEDLQDIRVGDVIYLTGTLVTCRDVCHRRLIELK
                     RPIPYDLNGKAIFHAGPIVRKNGDKWEMVSVGPTTSMRMESFEREFIEQTGVKLVVGK
                     GGMGPLTEEGCQKFKALHVIFPAGCAVLAATQVEEIEEVHWTELGMPESLWVCRVKEF
                     GPLIVSIDTHGNNLIAENKKLFAERRDPIVEEICEHVHYIK"
     gene            complement(44023..44934)
                     /gene="ttdA"
                     /locus_tag="IRB70_001158"
     CDS             complement(44023..44934)
                     /gene="ttdA"
                     /locus_tag="IRB70_001158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L(+)-tartrate dehydratase subunit alpha"
                     /protein_id="HBC0631100.1"
                     /translation="MMSESNKQQAVNKLTEIVANFTAMISTRMPDDVVDKLKQLKDAE
                     TSSMGKIIYHTMFDNMQKAIDLNRPACQDTGEIMFFVKVGSRFPLLGELQSILKQAVE
                     EATVKAPLRHNAVEIFDEVNTGKNTGSGVPWVTWDIIPDNDDAEIEVYMAGGGCTLPG
                     RSKVLMPSEGYEGVVKFVFENISTLAVNACPPVLVGVGIATSVETAAVLSRKAILRPI
                     GSRHPNPKAAELELRLEEGLNRLGIGPQGLTGNSSVMGVHIESAARHPSTIGVAVSTG
                     CWAHRRGTLLVHADLTFENLSHTRSAL"
     gene            45141..46073
                     /gene="ttdR"
                     /locus_tag="IRB70_001159"
                     /gene_synonym="dan"
     CDS             45141..46073
                     /gene="ttdR"
                     /locus_tag="IRB70_001159"
                     /gene_synonym="dan"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TtdR"
                     /protein_id="HBC0631101.1"
                     /translation="MLNSWPLAKDLQVLVEIVHSGSFSAAAATLGQTPAFVTKRIQIL
                     ENTLATTLLNRSARGVALTESGQRCYEHALEILTQYQRLVDDVTQIKTRPEGMIRIGC
                     SFGFGRSHIAPAITELMRNYPELQVHFELFDRQIDLVQDNIDLDIRINDEIPDYYIAH
                     LLTKNKRILCAAPEYLQKYPQPQSLQELSRHDCLVTKERDMTHGIWELGNGQEKKSVK
                     VSGHLSSNSGEIVLQWALEGKGIMLRSEWDVLPFLESGKLVRVLPEYAQSANIWAVYR
                     EPLYRSMKLRVCVEFLAAWCQQRLGKPDEGYQVM"
     gene            complement(46086..46703)
                     /gene="plsY"
                     /locus_tag="IRB70_001160"
     CDS             complement(46086..46703)
                     /gene="plsY"
                     /locus_tag="IRB70_001160"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBC0631102.1"
                     /translation="MSAIAPGMILIAYLCGSISSAILVCRLCGLPDPRTSGSGNPGAT
                     NVLRIGGKGAAVAVLIFDVLKGMLPVWGAYELGVSPFWLGLIAIAACLGHIWPVFFGF
                     KGGKGVATAFGAIAPIGWDLTGVMAGTWLLTVLLSGYSSLGAIVSALIAPFYVWWFKP
                     QFTFPVSMLSCLILLRHHDNIQRLWRRQETKIWTKFKRKREKDPE"
     gene            46808..47176
                     /gene="folB"
                     /locus_tag="IRB70_001161"
     CDS             46808..47176
                     /gene="folB"
                     /locus_tag="IRB70_001161"
                     /EC_number="4.1.2.25"
                     /EC_number="5.1.99.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional dihydroneopterin
                     aldolase/7,8-dihydroneopterin epimerase"
                     /protein_id="HBC0631103.1"
                     /translation="MDIVFIEQLSVITTIGVYDWEQTIEQKLVFDIEMAWDNRKAAKS
                     DDVADCLSYADIAETVVSHVEGARFALVERVAEEVAELLLARFNSPWVRIKLSKPGAV
                     ARAANVGVIIERGNNLKENN"
     gene            47267..48088
                     /gene="bacA"
                     /locus_tag="IRB70_001162"
     CDS             47267..48088
                     /gene="bacA"
                     /locus_tag="IRB70_001162"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBC0631104.1"
                     /translation="MSDMHSLLIAAILGVVEGLTEFLPVSSTGHMIIVGHLLGFEGDT
                     AKTFEVVIQLGSILAVVVMFWRRLFGLIGIHFGRPLQHEGESKGRLTLIHILLGMIPA
                     VVLGLLFHDTIKSLFNPINVMYALVVGGLLLIAAECLKPKEPRAPGLDDMTYRQAFMI
                     GCFQCLALWPGFSRSGATISGGMLMGVSRYAASEFSFLLAVPMMMGATALDLYKSWGF
                     LTTGDIPMFAVGFITAFVVALIAIKTFLQLIKRISFIPFAIYRFIVAAAVYVVFF"
     gene            complement(48168..49406)
                     /gene="cca"
                     /locus_tag="IRB70_001163"
     CDS             complement(48168..49406)
                     /gene="cca"
                     /locus_tag="IRB70_001163"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused tRNA nucleotidyltransferase/2',3'-cyclic
                     phosphodiesterase/2' nucleotidase/phosphatase Cca"
                     /protein_id="HBC0631105.1"
                     /translation="MKIYLVGGAVRDALLGLPVKDRDWVVVGSTPQEMLDAGYQQVGR
                     DFPVFLHPQTHEEYALARTERKSGSGYTGFTCYAAPDVTLEDDLKRRDLTINALAQDD
                     NGEIIDPYNGLGDLQNRLLRHVSPAFGEDPLRVLRVARFAARYAHLGFRIADETLALM
                     REMTHAGELEHLTPERVWKETENALTTRNPQVFFQVLRDCGALRVLFPEIDALFGVPA
                     PARWHPEIDTGIHTLMTLSMAAMLSPQVDVRFATLCHDLGKGLTPPELWPRHHGHGPA
                     GVKLVEQLCQRLRVPNEIRDLARLVAEFHDLIHTFPMLNPKTIVKLFDSIDAWRKPQR
                     VEQLALTSEADVRGRTGFESADYPQGRWLREAWEVAQSVPTKAVVEAGFKGVEIREEL
                     TRRRIAAVASWKEQRCPKPD"
     gene            complement(49470..50090)
                     /locus_tag="IRB70_001164"
     CDS             complement(49470..50090)
                     /locus_tag="IRB70_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SH3 domain-containing protein"
                     /protein_id="HBC0631106.1"
                     /translation="MPKLRLIGLTLLALSATAVSHAEETRYVSDELNTWVRSGPGDHY
                     RLVGTVNAGEEVTLLQTDANTNYAQVKDSSGRTAWIPLKQLSTEPSLRSRVPDLENQV
                     KTLTDKLTNIDNTWNQRTAEMQQKVAQSDSVINGLKEENQKLKNELIVAQKKVDAASV
                     QLDDKQRTIIMQWFMYGGGVLGLGLLLGLVLPHLIPSRKRKDRWMN"
     gene            50332..51633
                     /gene="ygiF"
                     /locus_tag="IRB70_001165"
     CDS             50332..51633
                     /gene="ygiF"
                     /locus_tag="IRB70_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic triphosphatase"
                     /protein_id="HBC0631107.1"
                     /translation="MAQEIELKFIVNHSAVEALRDHLNTLGGEHHDPVQLLNIYYETP
                     DNWLRGHDMGLRIRGENGRYEMTMKVAGRVTGGLHQRPEYNVALSEPTLDLAQLPTEV
                     WPNGELPTDLASRVQPLFSTDFYREKWLVEVDGSQIEIALDQGEVKAGEFAEPICELE
                     LELLSGDTRAVLKLANQLVSQTGLRQGSLSKAARGYHLAQGNPAREIKPTTILHVAAK
                     ADVEQGLEAALELALAQWQYHEELWVRGNDAAKEQVLAAIGLVRHTLMLFGGIVPRKA
                     STHLRDLLTQCEATIASAVSAVTAVYSTETAMAKLALTEWLVSKAWQPFLDAKAQSKM
                     SDSFKRFADIHLSRHAAELKSVFCQPLGDRYRDQLPRLTRDIDSILLLAGYYDPVVAQ
                     AWLENWQGLRHAIVTGQRIEIEHFRNEANNQEPFWLHSGKR"
     gene            51656..54496
                     /gene="glnE"
                     /locus_tag="IRB70_001166"
     CDS             51656..54496
                     /gene="glnE"
                     /locus_tag="IRB70_001166"
                     /EC_number="2.7.7.42"
                     /EC_number="2.7.7.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional [glutamate--ammonia
                     ligase]-adenylyl-L-tyrosine
                     phosphorylase/[glutamate--ammonia-ligase]
                     adenylyltransferase"
                     /protein_id="HBC0631108.1"
                     /translation="MKPLSSPLQQYWQTVVERLPEPLADESLSAQAKSVLTFSDFVQD
                     SVIAHPEWLTELESQPPQADEWQHYSAWWQEALSNVSDEAGLMRELRLFRRRIMVRIA
                     WAQTLALVTEESILLQLSHLAETLIVAARDWLYDACCREWGTPCNAQGEAQPLLILGM
                     GKLGGGELNFSSDIDLIFAWPEHGCTQGGRRELDNAQFFTRMGQRLIKVLDQPTQDGF
                     VYRVDMRLRPFGESGPLVLSFAALEDYYQEQGRDWERYAMVKARIMGDSEGVYANELR
                     AMLRPFVFRRYIDFSVIQSLRNMKGMIAREVRRRGLTDNIKLGAGGIREIEFIVQVFQ
                     LIRGGREPSLQSRSLLPTLSAIAELHLLSENDAEQLRVAYLFLRRLENLLQSINDEQN
                     QTLPSDELNRARLAWAMDFADWQQLTGALIGHMTNVRRVFNELIGDDESETQEESLSE
                     QWRELWQDALQEDDTTPVLAHLSEDDRKQVLTLIADFRKELDKRTIGPRGRQVLDHLM
                     PHLLRDVCTREDAAVTLSRITALLVGIVTRTTYLELLSEFPAALKHLISLCAASPMIA
                     SQLARYPLLLDELLDPNTLYQPTATDAYRDELRQYLLRVPEDDEEQQLEALRQFKQAQ
                     LLRIAAADIAGTLPVMKVSDHLTWLAEAMIDAVVQQAWVQMVARYGKPNHLNEREGRG
                     FAVVGYGKLGGWELGYSSDLDLIFLHDCPMDAMTDGEREIDGRQFYLRLAQRIMHLFS
                     TRTSSGILYEVDARLRPSGAAGMLVTSAEAFADYQKNEAWTWEHQALVRARVVYGDPQ
                     LTAHFDAVRREIMTLPREGKTLQTEVREMREKMRAHLGNKHRDRFDIKADEGGITDIE
                     FITQYLVLRYAHEKPKLTRWSDNVRILELLAQNDIMEEQEAMVLTRAYTTLRDELHHL
                     ALQELPGHVSEDCFTAERDLVRASWQKWLVEE"
     gene            54544..55977
                     /gene="hldE"
                     /locus_tag="IRB70_001167"
     CDS             54544..55977
                     /gene="hldE"
                     /locus_tag="IRB70_001167"
                     /EC_number="2.7.1.167"
                     /EC_number="2.7.7.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     D-glycero-beta-D-manno-heptose-7-phosphate
                     kinase/D-glycero-beta-D-manno-heptose 1-phosphate
                     adenylyltransferase HldE"
                     /protein_id="HBC0631109.1"
                     /translation="MKVTLPEFERAGVMVVGDVMLDRYWYGPTSRISPEAPVPVVKVN
                     TIEERPGGAANVAMNIASLGANARLVGLTGIDDAARALSKSLADVNVKCDFVSVPTHP
                     TITKLRVLSRNQQLIRLDFEEGFEGVDPQPLHERINQALSSIGALVLSDYAKGALASV
                     QQMIQLARKAGVPVLIDPKGTDFERYRGATLLTPNLSEFEAVVGKCKTEEEIVERGMK
                     LIADYELSALLVTRSEQGMSLLQPGKAPLHMPTQAQEVYDVTGAGDTVIGVLAATLAA
                     GNSLEEACFFANAAAGVVVGKLGTSPVSPIELENAVRGRADTGFGVMTEEELKFAVAA
                     ARKRGEKVVMTNGVFDILHAGHVSYLANARKLGDRLIVAVNSDASTKRLKGDSRPVNP
                     LEQRMIVLGALEAVDWVVSFEEDTPQRLIAGILPDLLVKGGDYKPEEIAGSKEVWANG
                     GEVLVLNFEDGCSTTNIIKKIQQDKKG"
     gene            complement(56097..56156)
                     /locus_tag="IRB70_001168"
     CDS             complement(56097..56156)
                     /locus_tag="IRB70_001168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HBC0631110.1"
                     /translation="MMKLVIILIVLLLVSFATY"
     gene            complement(56396..58057)
                     /locus_tag="IRB70_001169"
     CDS             complement(56396..58057)
                     /locus_tag="IRB70_001169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBC0631111.1"
                     /translation="MDDIVNSVPSWMFTAIIAVCILFIIGIIFARLYRRASAEQAFVR
                     TGLGGQKVVMSGGAIVMPIFHEIIPINMNTLKLEVSRSTIDSLITKDRMRVDVVVAFF
                     VRVKPSVEGIATAAQTLGQRTLSPEDLRMLVEDKFVDALRATAAQMTMHELQDTRENF
                     VQGVQNTVAEDLSKNGLELESVSLTNFNQTSKEHFNPNNAFDAEGLTKLTQETERRRR
                     ERNEVEQDVEVAVREKNRDALSRKLEIEQQEAFMTLEQEQQVKTRTAEQNAKIAAFEA
                     ERRREAEQTRILAERQIQETEIDREQAVRSRKVEAEREVRIKEIEQQQVTEIANQTKS
                     IAIAAKSEQQSQAEARANLALAEAVSAQQNVETTRQTAEADRAKQVALIAAAQDAETK
                     AVELTVRAKAEKEAAEMQAAAIVELAEATRKKGLAEAEAQRALNDAINVLSDEQTSLK
                     FKLALLQALPAVIEKSVEPMKSIDGIKIIQVDGLNRGGATGDANTGNVGGGNLAEQAL
                     SAALSYRTQAPLIDSLLNEIGVSGGSLAALTSSLSSTTPVEEKAE"
     gene            complement(58084..58713)
                     /locus_tag="IRB70_001170"
     CDS             complement(58084..58713)
                     /locus_tag="IRB70_001170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1449 family protein"
                     /protein_id="HBC0631112.1"
                     /translation="MILFADYNTPYLFAISFVLLIGLLEIFALICGHMLSGALDAHLD
                     HYDSITTGHISQALHYLNIGRLPALVVLCLLAGFFGLIGILLQHTCIMVWQSPLSNLF
                     VVPVSLLFTIIAVHYTGKIVAPWIPRDHSSAITEEEYIGSMALITGHQATSGNPCEGK
                     LTDQFGQIHYLLLEPEEGKIFTKGDKVLIICRLSATRYLAENNPWPQIL"
     gene            58982..59182
                     /gene="glgS"
                     /locus_tag="IRB70_001171"
     CDS             58982..59182
                     /gene="glgS"
                     /locus_tag="IRB70_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell surface composition regulator GlgS"
                     /protein_id="HBC0631113.1"
                     /translation="MDHSLNSLNNFDFLARSFARMHAEGRPVDILAVTGNMDEEHRTW
                     FCARYAWYCQQMMQTRELELEH"
     gene            complement(59217..59516)
                     /gene="ubiK"
                     /locus_tag="IRB70_001172"
     CDS             complement(59217..59516)
                     /gene="ubiK"
                     /locus_tag="IRB70_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311957.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis accessory factor UbiK"
                     /protein_id="HBC0631114.1"
                     /translation="MIDPKKIEQIARQVHESMPKGIREFGEDVEKKIRQTLQAQLTRL
                     DLVSREEFDVQTQVLLRTREKLALLEQRISELEARNNSVADLQSPPAIPPIDKAE"
     regulatory      59638..59786
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            59890..60543
                     /gene="ribB"
                     /locus_tag="IRB70_001173"
     CDS             59890..60543
                     /gene="ribB"
                     /locus_tag="IRB70_001173"
                     /EC_number="4.1.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3,4-dihydroxy-2-butanone-4-phosphate synthase"
                     /protein_id="HBC0631115.1"
                     /translation="MNQTLLSSFGTPFERVENALAALREGRGVMVLDDEDRENEGDMI
                     FPAETMTVEQMALTIRHGSGIVCLCITEDRRKQLDLPMMVENNTSAYGTGFTVTIEAA
                     EGVTTGVSAADRITTVRAAIADDAKPSDLNRPGHVFPLRAQAGGVLTRGGHTEATIDL
                     MTLAGFKPAGVLCELTNDDGTMARAPECIEFANKHNMALVTIEDLVAYRQAHERKAS"
     gene            60805..60975
                     /locus_tag="IRB70_001174"
     CDS             60805..60975
                     /locus_tag="IRB70_001174"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631116.1"
                     /translation="MFIAWYWIVLIALVVVGYFLHLKRYCRAFRQDRDALLEARNKYL
                     NSTREETAEKVE"
     gene            complement(61033..61806)
                     /gene="zupT"
                     /locus_tag="IRB70_001175"
     CDS             complement(61033..61806)
                     /gene="zupT"
                     /locus_tag="IRB70_001175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc transporter ZupT"
                     /protein_id="HBC0631117.1"
                     /translation="MSVPLILTILAGAATFIGAFLGVLGQKPSNRLLAFSLGFAAGIM
                     LLISLMEMLPAALAAEGMSPVLGYGMFIFGLLGYFGLDRMLPHAHPQDLMQKSVQPLP
                     KSIKRTAILLTLGISLHNFPEGIATFVTASSNLELGFGIALAVALHNIPEGLAVAGPV
                     YAATGSKRTAILWAGISGLAEILGGVLAWLILGSMISPVVMAAIMAAVAGIMVALSVD
                     ELMPLAKEIDPNNNPSYGVLCGMSVMGFSLVLLQTAGIG"
     gene            61949..62737
                     /gene="ygiD"
                     /locus_tag="IRB70_001176"
     CDS             61949..62737
                     /gene="ygiD"
                     /locus_tag="IRB70_001176"
                     /EC_number="1.13.11.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001356237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4,5-DOPA dioxygenase extradiol"
                     /protein_id="HBC0631118.1"
                     /translation="MSSTRMPALFLGHGSPMNVLEDNLYTRSWQTLGMTLPRPQAIVV
                     VSAHWFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPALAQHLVELLAPVPVT
                     LDKEAWGFDHGSWGVLIKMYPDADIPMVQLSIDSSKPAAWHFEMGRKLAALRDEGIML
                     VASGNVVHNLRTVKWHGDSSPYPWATSFNEYVKANLTWQGPVEQHPLVNYLDHEGGAL
                     SNPTPEHYLPLLYVLGAWDGQEPITIPVDGIEMGSLSMLSVQIG"
     gene            complement(62783..63454)
                     /gene="dsbI"
                     /locus_tag="IRB70_001177"
     CDS             complement(62783..63454)
                     /gene="dsbI"
                     /locus_tag="IRB70_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000511507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide oxidoreductase DsbI"
                     /protein_id="HBC0631119.1"
                     /translation="MGIKGMWKDLRTSPVDTLVRWQEQRLLWLLMAVAMGALIILAHS
                     FFQIYLYMAPCEQCVYIRYAMFVMVIGGLVAAINPKNIILKLIGCVMAFYGSILGLKF
                     SLKLNDIHHAVHNPDPDSLFGVQGCSTDPTFPFNLPLAQWAPNWFKPTGDCGYDAPIV
                     PDDVTLSSTQQWFVEMYQQSEGWYLLPPWHFMNMAQACMLAFGMCLVLLVIMSGAWAL
                     KIIRG"
     gene            complement(63469..64137)
                     /locus_tag="IRB70_001178"
     CDS             complement(63469..64137)
                     /locus_tag="IRB70_001178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA/DsbL"
                     /protein_id="HBC0631120.1"
                     /translation="MSKLGISSLFKSILLTAALAVSFTASAFTEGTDYMVLEKPIPNA
                     DKTLIKVFSYACPFCYKYDKAVTGPVSEKVKDIVAFTPFHLETKGEYGKQASEVFAVL
                     INKDKAAGISLFDANSQFKKAKFAYYAAYHDKKERWSDGKDPAAFIKTGLDAAGMSQA
                     DFEAALKEPAVQETLEKWKASYDVAKIQGVPAYVVNGKYLIYTKSIKSIDAMADLIRE
                     LASK"
     gene            complement(64155..65951)
                     /locus_tag="IRB70_001179"
     CDS             complement(64155..65951)
                     /locus_tag="IRB70_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aryl-sulfate sulfotransferase"
                     /protein_id="HBC0631121.1"
                     /translation="MFDKYRKTLVAGTVAITLGLSASGVMAAGFKPAPPAGQLGAVIV
                     DPYGNAPLTALVDLDSHVISDVKVTVHGKGEKGVEISYPVGQESLKTYDGVPIFGLYQ
                     KFANKVTVEWKENGKVMKDDYVVHTSAIVNNYMDNRSISDLQQTKVVKVAPGFEDRLY
                     LVNTHTFTAQGSDLHWHGEKDKNAGILDAGPATGALPFDIAPFTFIVDTEGEYRWWLD
                     QNTFYDGRDRNINKRSYLMGIRETPRGTFTAVQGQHWYEFDMMGQVLEDHKLPRGFAD
                     ATHESIETPNGTVLLRVGKSNYRRDDGVHVTTIRDHILEVDKSGRVVDVWDLTKILDP
                     KRDALLGALDAGAVCVNVDLAHAGQQAKLEPDTPFGDALGVGPGRNWAHVNSIAYDAK
                     DDSIILSSRHQGVVKIGRDKLVKWILAPSKGWEKPLASKLLKPVDANGKPITCNENGL
                     CENSDFDFTYTQHTAWISSKGTLTIFDNGDGRHLEQPALPTMKYSRFVEYKIDEKKGT
                     VQQVWEYGKERGYDFYSPITSIIEYQADRNTMFGFGGSIHLFDVGQPTVGKLNEIDYK
                     TKEVKVEIDVLSDKPNQTHYRALLVRPQQMFK"
BASE COUNT        16068 a        16628 c        17441 g        16116 t
ORIGIN      
        1 ataatgtaaa actgattaaa tggtggcgaa aattaatcga ttattacggc tcgggcctgt
       61 cttacttctg tgcacatcat ttttcgcaca atctaatatg actgtatatc ctatgtctgt
      121 atctataaac agtcagggag aaggaagtgt tcgtgtaata tcgaaaacga atgaagtcca
      181 atatataaag gcaaccgtat ttcgtatcga taatccatca acaccacaag aaaaagaaat
      241 cgaagtaact tcaggcgatg caaaccaact tgtgataatg ccgcccaaat ttgctttgcc
      301 tggcggtagt agcaaaaccg tgcgttttgt ggcaatggaa cctgagcaaa aagaaaaaaa
      361 ctatcgggtt aaatttgaag ctgtacccag cattgatgat gcaacagata ataaaaaaga
      421 tctctccatg caattaacgg ttaacttaat ttgggggatt gttgtcagcg tgccacctca
      481 gcagcctgtg gcaaagttag atattaacgc cgataaaaag ctaatcaata atggcaatca
      541 acgtctgaag atattaacca ttgcctattg taaaaatagt ggttctgcgg agtgcagaac
      601 acagaccgta aataaaaaca ttttccctgg tcaggaaaga gttttagaaa gcatatctgg
      661 ctacgataaa atcgttgtca aatataataa ctggatcacc aaggacaatg gcgagtttga
      721 gctggcggtc cattaattat cattgtaata aaccaaggaa tagtaatgaa aaaggtattc
      781 gcaaaatctc ttatggtagc ggcaatgttt tccgttgcag gttctgcatt agcagtacaa
      841 aaagatatca ctgttactgc taacgttgat gctgctctgg atatgacgca gaccgataac
      901 actgcactgc cgaaggcagt agaaatgcaa tatctgccag gtcagggtct gcaatcttac
      961 cagttaatga ctaaaatctg gtcaaatgac acgaccaaag acgtgaaaat gcagttagtt
     1021 tcgcctgcgc aactggttca gagcctggac gctagcaaaa ttgttccgct gaccgtaacc
     1081 tggggtggtg aagagattaa agctgatgcg gcaaccactt ttaccgcaac gaaaatcttt
     1141 gcttccgatg cgttaactaa cggttcgctg gctaaaccac tgatgttttc ccaggctacc
     1201 aaaggtgttc tggaaacggg tatctaccgt ggcgtagtta gcatttatct gtcccaggct
     1261 ctctaatctg gataacagaa ttaacatgca ataaagggag gcaagtcctc ccttctttta
     1321 actattttag tatttattat ggattacagg acagccatgg acaaaaaatt actggctctt
     1381 ttgatcctgg cgagtctcag cccggcaaag gcaacattaa caaaaattcc cgctggtttt
     1441 gaggttattg ctcagggaca gcaggagtat atcgaggttt attttgcagg gaaaagtctc
     1501 ggtaaatatt atgctatggt taatcttgat accgtaacct ttcttgattc atcaagttta
     1561 tacagcaaac ttgaattgag cactgacgat caaaaaatcg ctcatacagt taaagaaaaa
     1621 ctatcgcaac ccttagctcg ccacggtgaa ctggcttgtg gttttgtacg tactgattca
     1681 ggatgcggtt ttcttaatac tgagacagta gaaataatct acaatgatga agaaagttca
     1741 gcaaccctat ttcttaatcc gcaatggagt tctgcgttta actcgaagtc attgtattta
     1801 aatccagaca aaaatacggt taacgctttt atacatcagc aagatattaa tgtgctggta
     1861 caggatgatt accaatcgtt gtcaattcag ggtaatggcg cactgggaat aacagaaaat
     1921 agctatattg gtgcgcactg gaatttcgac ggttatgatg cagatgatgt cagcgacaac
     1981 aatgtcgatg tcagcgatct ctattaccgc tatgattttt tacgccgtta ttatgtgcag
     2041 gcggggcgga tggacaaccg cacattattt aatgcgcaag gtggaaactt tacttttaac
     2101 ttcctgccac tcggtgcaat agacggaatg cgtatcgggt cgactctcag ttatttaaac
     2161 cagacgcaaa gccagcaggg aacgccggta atgatcctgc tttcgcgcaa ttctcgtgtt
     2221 gatgcttatc gtaatgaaca actgttggga tcgttttacc tcaatagtgg ttcgcaattt
     2281 attgatacca gttcctttcc gccaggcagc tacagcgtgg cgttaaaagt ttatgaaaat
     2341 aaccaactca cccgcaccga gcttgtaccg tttaccaaaa ccggcggtct gacagacgga
     2401 aatgcccagt ggttcttgca ggcaggtaaa accacatcac aggtttctga tgatgaaagt
     2461 tctgcttatc agctaggcgt acgcctgcca ttacatccgc aatatgagct ctacgcagga
     2521 ctggcgaatg ccgatgatgt aagtgctttc gagttaggca ataactggac ggcagattta
     2581 ggcggggcgg ggaatctggc tatcagtgcc agcgtgttcc gtaacgatga cggcggcaaa
     2641 ggcgatatgc aacaggccaa ctggagtcat ccgggatggc cgacgttggg cttttatcgg
     2701 accaactctg acggtgatgc ttgtacaacc gacaacagag agagctacaa cgccttaagc
     2761 tgttatgaaa gtatttccgc gacggtttca cagaattttg tcggctggaa tatgatgctg
     2821 ggctataccc gcacacaaaa taacactgat gatagtttgc gctgggacaa acagcagagc
     2881 tttgaaaata actatcttcg ccagacttcg gctcaaagca tttccgagac cgtacaactt
     2941 agcgcttctc gcgcttttgt gatgcgtgac tggattttga gtacttccct tggggttttc
     3001 catcgtaatg acaacggcgg tggtagcgat gacaacggtt tgtatctgtc gttttcgtta
     3061 tctgatacgc caacgatgga cagcaataac aacagccatt caaccaatgt ttctactgat
     3121 tatcgttata gcgatcagga tggcgatcaa acgtcatggc agttatcgca taccttttat
     3181 aacgactcat tcagccataa agagcttggc gtgaccgtcg gcggtttgaa caccgatacc
     3241 ataaacagcg cggttaacgg gcgttgggat ggccaatatg gaaatgtcta cgctactgtc
     3301 tcagacagtt atgatcgcca gaaccatgat catctctcgg ccttcaccgg gacatacagc
     3361 tccacgctgg cggtgagtcg ctatggcatc aatttggggg ccagcggctc agatgatttg
     3421 ctgggagcgg tgttggtgga tgtgaaaggt ttctctgaac aggatgaaca gagtcagggt
     3481 ctgcaactcg aagcgcgggt ggctggcagc agaacattgc agcttggtca aagcgacagc
     3541 gtgttattcc cctatcctgg atttcagtct ggctttgttg aagttaacga cagtaatcag
     3601 ggtaaccagc aaggaacaac caacatcatt aacggtgcgg gaaatcgtga gttaatgctg
     3661 ttgccgggca aattacgtta tcgcgaagtg tctgccagtt ttaattacaa ctatattggt
     3721 cgtttgttat tgcccgcatc ggtagagaaa ttcccgctgg tgggtctgaa tagcgccatg
     3781 ttactggtgg ctgaagatgg cggattcaca cttgagatca gcagtggtga aaaagagttg
     3841 tatctgcttt ccgggcagca gttcctgaaa tgtccgctga atgttttgaa gaaacgcgcc
     3901 agcattcgct atagcgggga tgtgaattgt agcgtggtga gttattcaca attgccggaa
     3961 tctattcagg ttcaggcaca gttgaaacag cctaaattac gtggaaacgt ccagacggcg
     4021 caaagggagg ttgcaccatg agaaatcgat taattgccgt gattttatgt ttatttggca
     4081 tggtcgcggg ggggcacgct acgccaaatg tgacggctga aattacttat gatttggccg
     4141 ctggtagggc ggattattac ttctggaata gggaagatcc ccccgcagta agctacaaca
     4201 cgacatggtc aagttataaa tgcgattttc ctgatgtgca gcagacctgt accgcatcag
     4261 gaaatttatc aacagtgaaa atatatttga cagaaaaacg cagtggaatg cgttggcccg
     4321 tcaaactcaa aggctatgtt gatgcggagg tctggaaccc gggtggagtc tgtaacggat
     4381 ggtcgacgca aatcgcgtta gctaacggta cgggttatca atgtaaaagt gcttcagacg
     4441 gttatataca acatcttgcg agcgcaaagc cgatgacgct ctatcttgaa cagtccgaaa
     4501 tgaaaaattt accaatcggt ggtgtttggg aaggttcggt caaattgcag tttactaatc
     4561 cgtctacgga ttatcgcgcc gatattacgc ttaatgtcct cgatcccaac catatcgacg
     4621 tgttcttccc ggagttcgcc cacgctacgc cacgcgtaca actggatttg catccaacag
     4681 gcagcgttaa cggcaacaac tacgcgcaag atctgactat gttggatatg tgcctgtacg
     4741 atggctttaa cggtaacggt cttagctatg aaattttgct aaaagatgag ggaagaacgg
     4801 cggcaggacg cagtaatggt gagttttcga tttatcgtca gggcgcgagc tcaacggatg
     4861 aaggggagcg tattgattac cgtgtcaaaa tgtacgaccc ggaatcaggt gggcaaatcg
     4921 atgtgcgcaa caatgagagc atggtctgga ccaacatcaa ccttaaacgt gtccgcccgg
     4981 tggtgcttcc aggcattcgt tacgctgtga tgtgtgttcc cacaccgctg acgctggtgg
     5041 tcgacaaatt taacgtgacg gcaaaacagg cgggatatta tatgggtaaa ttgtcggtca
     5101 tctttacccc gtcattgccg acaatcaatt gacctcgcag accagaaaaa actaaacaac
     5161 gaagccgcct gaagaggcgg cttcgtcatt acgacttaca ttaagcgtta atgttgcggt
     5221 gcgggatcgt tatgtgattc ctgcgccacc tcaatcgccg gtttgttctg caacacggtc
     5281 cagataacca gcgcacctaa caggtcgaac actgccagaa ctgcgaacag cgggctgaag
     5341 ccgatggtgt cagccagtgc accgactacc agtgcaaaca gcgtacttgc cagccatgcg
     5401 gacatcccgg ttaaaccgtt cgccgtcgcc acttcgttac gaccgaacac gtcagaagag
     5461 agcgtaatca gtgcgccaga cagtgcctgg tgagcaaaac caccgataca cagcagcata
     5521 atcgcgacat acgggttggt gaacagaccg atcatacccg ggccaatcat cagcacagca
     5581 cccagcgtta cgaccatctt acgggaaacg atcaggttca caccaaacca acgctggaac
     5641 agcggcggca ggtaaccacc gaggatacaa ccgaggtcag caaacagcat cggcatccag
     5701 gcaaacatcg cgatctcttt caggttaaag ccgtaaactt taaacatgaa cagcgggatc
     5761 cacgcgttaa aagtacccca tgccggttct gccaggaagc gcggcagcgc gataccccag
     5821 aactgacggt tgcgcaggat ctgaccaacg gacattttct tcgctgtgtc aacctggtgc
     5881 tgggcttcct gaccattaat aatgtagtcg cgttcttcat cggtcagatg tttctggtcg
     5941 cgcggatgct tgtagaaaat cagccatgcc atcgcccaga taaagctcaa cgcaccggag
     6001 atgataaatg ccatctgcca gctgtgcatc acgattgccc ataccaccag cggcggcgca
     6061 atcatcgcac caatcgaaga acctacgtta aagtaaccta ccgcgatgga acgctctttc
     6121 gccgggaacc attcggagct ggctttcaga cccgccggaa tcatcgcggc ttccgcggca
     6181 ccgaccgcac cacgagcaac agccaggcca ccccaactac ctgccagcgc ggttgcacca
     6241 cagaatacgg cccacagtac agcaaacatt gcataaccga ttttcgtacc cagcacatcc
     6301 agtacataac ccgctaccgg ttgcatgacc gtataagcag cagaatacgc tgcgatgata
     6361 taggaatact gttgggtgga gatgtttaac tcttccatca gagttggcgc agctgccgcc
     6421 acagtgttac gcgtcaggta accaagcacg gtgccgagcg tcaccagtgc gatcatatac
     6481 caacgtaacc ctttaatttt acgcatgtaa aacctcatcg ttttgttata tccgcaggaa
     6541 gcgcggccat catcccgcca gaggctgaag atgttagtta cgaccgggta accgaaaaaa
     6601 aaccggcacg ccccgaacgt tgccatgaaa gtttcgtgct aattcggctt ccgtaccggt
     6661 taacccgatt catctaacaa atgaatgaat cggcaatttg cattccgtcg acttatgatt
     6721 tgcgacggca gaaagataac ttgtcataca actttaaaag gtgagagcca tcacaaatgt
     6781 gcgaatattt gtagggacat tacctgacga ccacgaggcc agtactggcg cggcctgcag
     6841 cgagatttac cactttgaga gtaatttttt taactacgtt tattgatcta actcacgaaa
     6901 atatcttcgg actctggaaa ttggtgtgat aactttgtca gcatcgcacc ataagcaagc
     6961 tagctcactc gttgagagga agacgaaaat gactccgttt atgactgaag atttcctgtt
     7021 agataccgaa tttgcccgcc gtctgtatca cgactacgca aaagaccagc cgattttcga
     7081 ttaccattgc catttgccgc cgcagcagat tgcggaagac tatcgtttta aaaacctgta
     7141 tgacatctgg ttgaagggcg atcactacaa atggcgcgct atgcgtacca acggtgtggc
     7201 cgagcgtctg tgcaccggtg atgcgtctga ccgtgaaaaa tttgacgcct gggcggcgac
     7261 tgttccgcat actatcggca acccgttata ccactggacg cacctcgaac tgcgtcgtcc
     7321 gtttggtatc actggcaaat tgctttctcc gtcaactgcc gatgaaatct ggaacgaatg
     7381 taacgaattg ctggcgcagg ataatttctc tgcacgcggc atcatgcagc agatgaacgt
     7441 gaaaatggtc ggcaccaccg atgacccgat cgattctctg gagcatcacg cagagatcgc
     7501 caaagatggc tctttcacca ttaaagtgct gccgagctgg cgtccggaca aagcctttaa
     7561 cattgaacag gcgaccttta acgactacat ggcgaagctg ggcgaagttt ccgataccga
     7621 cattcgccgc tttgctgacc tgcaaacagc cctgactaaa cgtctggatc acttcgccgc
     7681 tcacggctgt aaagtgtctg accacgcgct ggatgtagtg atgtttgctg aagcgaacga
     7741 agcggaactg gacagcatcc tcgcgcgccg tctggcaggc gaaaccctga gcgagcacga
     7801 agtggcacag ttcaaaactg cggtgctggt gttcctcggc gctgaatacg cacgtcgcgg
     7861 ctgggtacag cagtaccaca ttggcgcact gcgtaataac aacctgcgtc agtttaaact
     7921 gctggggccg gatgtcggct ttgactccat caacgaccgt ccgatggcgg aagagctgtc
     7981 taagctgctg agcaagcaga acgaagaaaa cctgctgccg aaaaccattc tctactgcct
     8041 gaacccgcgc gataacgaag tgctgggcac catgatcggt aacttccagg gcgaaggtat
     8101 gccgggcaaa atgcagttcg gttccggctg gtggtttaac gaccagaaag acggtatgga
     8161 acgtcagatg acccaactgg cgcagctcgg tctgctgagc cgctttgtcg gtatgctgac
     8221 tgacagccgt agcttcctgt catacacccg tcacgaatac ttccgccgca ttctgtgcca
     8281 gatgatcggt cgctgggtag aagcgggtga agcaccggcg gacatcaacc tgctgggcga
     8341 gatggtgaaa aatatttgct ttaacaatgc gcgtgactac ttcgccattg aactgaacta
     8401 aggtctgggg ttgatatgca atacatcaag atccatgcgc tggataacgt cgcggttgct
     8461 ttagcggatt tggctgaagg cacagaagtc agtgtcgata accagactgt tacgctgcgc
     8521 caggatgttg ctcgtggaca taaatttgcg ttaacggata tcgcaaaagg ggccaacgtc
     8581 attaaatatg gcctgccgat tggttatgca ttggcggata ttgcggcggg tgaacacgtt
     8641 cacgcccaca atacgcgcac gaatctgagc gatctggatc agtatcgcta tcaacctgat
     8701 tttcaggatc tgcctgcgca agcggcagat cgtgaagtgc agatctatcg tcgcgcgaac
     8761 ggcgatgtcg gggtgcgtaa tgagctgtgg atcctgccaa ccgtgggttg tgttaacggc
     8821 atcgcgcggc agatccagaa ccgtttcctg aaagagacca acaacgctga aggtaccgac
     8881 ggcgtgttcc tcttcagcca cacctacggc tgctcacaac tgggcgacga tcacatcaat
     8941 actcgcacca tgctgcaaaa catggtgcgc cacccgaacg cgggcgcagt gctggtgatt
     9001 ggtctgggct gtgaaaacaa ccaggttgcc gcattccgtg aaacgttggg cgatatcgat
     9061 cctgaacgcg ttcatttcat gatctgccaa cagcaggatg atgaaatcga ggccgggatc
     9121 gcgcatttgc atcagttgta taacgtgatg cgcaacgaca agcgcgagcc gggcaaactc
     9181 agcgaactga agtttggtct ggagtgcggc ggttctgacg gtctttccgg tattaccgcc
     9241 aacccaatgc tcggtcgttt ctctgactac gtgattgcta acggtggtac taccgtactg
     9301 accgaagtgc cggagatgtt tggcgcagag cagttgctga tggaccattg ccgcgacgaa
     9361 gcaacgtttg aaaaactggt caccatggtc aacgacttca aacagtactt tattgcccat
     9421 gaccagccga tctacgaaaa cccatcaccg gggaacaaag cgggcggtat caccacgctg
     9481 gaagataaat cgcttggctg tacccagaaa gcgggttcca gtgtcgtggt tgacgtgctg
     9541 cgttacggcg agcgtctgaa aacgccgggg ctgaacttgt taagtgcgcc gggtaacgat
     9601 gccgtagcga ccagcgccct ggcgggtgcg ggctgccata tggtgctgtt cagtactggt
     9661 cgtggtacgc cgtatggtgg atttgtgccg acggtgaaaa tcgccaccaa cagtgaactg
     9721 gcggcgaaga aaaaacactg gatcgacttt gacgcgggtc agctgatcca cggtaaagcg
     9781 atgccgcagt tgctggaaga atttatcgac accatcgttg agtttgccaa cggtaaacaa
     9841 acctgcaacg agcgtaacga cttccgcgaa ctggcgatct tcaaaagcgg cgtaacgcta
     9901 taaagtcgaa atgagttgtt aataaaaaac ggcgtttcat aatgtgaagc gccgtttgct
     9961 tttccatacc tgctaaggat ttatcatgac cgcgtattgg ctggcccagg gcgtgggtgt
    10021 catcgccttt ctgattggta tcacaacatt tttcaatcgt gacgaacgtc gcttcaaaaa
    10081 gcaactttcg gtctatagcg ccgttattgg cgtacatttt tttcttctgg gcacctatcc
    10141 tgccggtgcc agtgccatcc ttaatgccat tcgtacattg attaccttac gcacgcgcag
    10201 cttatgggta atggcgattt ttattgtgct gactggtgga attggcctcg cgaagttcca
    10261 tcatcctgtc gaactactgc cggtaatcgg cacgattgtc agtacctggg cgctgttccg
    10321 ctgtaaaggg ctgaccatgc gctgcgtaat gtggttttca acgtgttgct gggtgattca
    10381 caacttctgg gcggggtcga taggcggcac gatgattgag gggagttttc tgctaatgaa
    10441 tggcctgaat atcattcgtt tctggcggat gcagaaaagg ggaattgatc cgtttaaagt
    10501 ggagaaaacc ccttccgccg tagacgaaag gggctaagta ttagttacgc agggcgctat
    10561 ttgccagacg atcgtcttcc gcctggcaag ctgccgcagt gaacagcacg tcagttgaag
    10621 agttcagcgc ggtttcgcaa gagtcctgca atacgccgat gataaagccg acggcaacca
    10681 cctgcatggc gatatcgttc gaaataccga acatattaca ggccagtggg atcagcagca
    10741 aagatccccc cgccacgccg gatgcgccac aggcacacag agaagccact acgctcaaca
    10801 gcagcgctgt gggcagatca accggaatac ccagcgtatt aaccgcagcc agcgtcaaca
    10861 cggtaatggt gattgctgcg cccgccatat tgatggtggc tcccagcgga atagaaacgg
    10921 aataggtatc gcgatccaga ttcagctttt cacacagcgc catattcacc ggaatgttcg
    10981 ccgcagagct gcgggtgaag aaggcataca cgccgctttc gcgcaggcac agcagcacca
    11041 gcgggaacgg gttacgacga atcttccacc acaccagcaa ggggttaacc accagcgcca
    11101 ccagtaacat acagccaacc agcacgacca gcagttgcgc gtagccccac agtgtggaga
    11161 aaccggtggt tgccagggta gaagaaacca gaccaaaaat accgatcggt gcgaagcgaa
    11221 tgaccagttt caccataaag gtgacggcat tcgacatatc gttgaccagg tttttggtgg
    11281 tctcgttacc gtgacgcagt gcgaaaccga ggccaattgc ccacaccagg atcccgatat
    11341 agttaccttt cagcagcgcg tcaatggggt tggaaaccat gctcattacc agcccgcgca
    11401 ttacttctac aatgcctgac ggcggcgaaa tatcacccgc gctactggac aagtgcaggg
    11461 tagaagggaa ggcaaaactg aagattactg cggccagagc agcagagaag gtgcccagca
    11521 gatagaggaa caaaataggg cggatattgg ttttctgccc gtgctggtgg ttagcaatag
    11581 atgccattac cagcatcaac accaggatgg gggcaacggc tttcagtgcg ccgacgaaca
    11641 aagtacctaa cagaccaaca gcttccgccg cgggttttga gatccatgcc agaagaatcc
    11701 ccagaacaag gccgaccagg atttgtttta ccaggctgcc atgagccaga cgccggaata
    11761 gccccggtga acgttgcgta gtcatttttc gatcctttca ttgtgttgtc gcacatccct
    11821 ggtgcgttct gtcgacgcat ctttcaggat gtaacaaagt gtttgcaagg tcgagtataa
    11881 ggaaagttac agcttcggga agcgaaaaat gctggatttt aaagagaggt catattttgc
    11941 aacttaatgg ttacatttat ttgacataaa aataaagccc aacgtgcggc ttccagactg
    12001 atgacaacgt caaaaaagta ctcggtcagt cccctcgccc cttttgggga gagggagaaa
    12061 acggtgctca tgttgatgac agggtacacg gcttaggcag attaaaaatt attctacccg
    12121 ctgcttatca tgccgataat tcacccaggc gttgataata aacgtcatca ccagaatgcc
    12181 aaacaccacg cccagcgaga cggcgatcgg aatatggtag aagtcgacaa tcagcatctt
    12241 gataccgata aacaccagaa tcaccgccag accatatttg agcatcgaga aacgctctgc
    12301 cacacctgcc agcaggaaat acatcgcacg caggccgagg atcgcaaaca ggtttgaggt
    12361 cagcacaata aacggatcgg tggtcacggc gaagatagcc ggaatactat ccacggcgaa
    12421 aatcacgtcg ctcaactcca ccagaatcag caccagcatc agcggcgtgg catacaacaa
    12481 accattctta cgcacaaaga aatgctcgtt gtcgatggtg tcggtcatgc gtaaatgacc
    12541 gcgtagccag cgcaccagcg gcttgtcgcc aatgcctgat tcatcttcat gagccagcgc
    12601 catcttcacg ccggtaaaca gcaggaaggc accgaagata tacaagatcc agtcgaactg
    12661 tgaaatcagc cagctaccag tgaagatcat gatggtacgc agaacaatcg ccccaagcac
    12721 gccatacacc agcacgcgac gttgtaatgc cgccggaaca gagaaatagc tgaacaacat
    12781 cagccagaca aagacgttat cgaccgccag cgatttctca atcagataac ccgtgagaaa
    12841 ggccagtgcc tgtggatcgg caacggcgcg accttcggtt tgcaccagat accaccagaa
    12901 agcggcgtta aacagtaacg acagcgtcac ccagaccagc gaccaggccg cagcctgttt
    12961 catggtcatg gcatgtgccc cacgacgccc ctgcaacaac aggtcgatag ccagcataat
    13021 ggtgacaaca acagcgaatc cgccccatag caacggcgtg ccgacagtat tcatagaagt
    13081 tccttacaca taaaaaaacg gccaacgtcg gaagacgtca gccgctgctt tttatgcata
    13141 gacctcgcct tccggcaagg tctcacttac aacaaaaaag gaatacgtct gcgtattcct
    13201 ttcgggttgc ccggtgaccg gatgtggttt ttcacacatc gtaatgacga tcgaccgaca
    13261 atgaagttac tcccctttgc aggtaacaaa gtatgacaga ccattcagtc agtcaatggt
    13321 ctgttacata ccttttacac tgttttactt tggcaattat agttttacgt tatctgccgg
    13381 aaaaatcacc ccagtctggc ggcggatctc agtcagcagt ttggcggtga tacgactgac
    13441 cgccagccct ggatgattca ccagatgctc atccaccagg gtagcgaaca gctctgcttc
    13501 gtagagcatg gtattaatat gctgtggctg ggtgagatcc tgcatctggc tgccacgcgg
    13561 tacaaagcag actttctggc attcagagag tttttcaatc accagcgatc ccgcttcgcc
    13621 ctgaatctcg cttgccagga cagaatcgct cacttttgag tgctgcaacg taacgctgaa
    13681 atcaccgtaa tccatcacca ccacgccgtg ggcatccaca ccgcttgcca gcaaactggc
    13741 ggttgcctgc acgcttttcg gttcaccgaa taatgccacc gccgacgcca ggcagtaaaa
    13801 gccgatatcc ataatcgaac cgttggagaa tgccggattg aaggtgttgg gattctctcc
    13861 gtccaggtaa cgctgatacc gcgaggaata ctggcaatag ttgaaaaaga ctttacgcag
    13921 tttgccgact ttcggcagcg cctggcgtaa cagatgaaag ttcggcaggt aggccgtttt
    13981 aaatgcctca aacagcacca cctgattttc ccgcgcacag gcaatggcgg catccacttc
    14041 cgcctgattc gacgccagtg gcttctcgca aatcacatga attttgtgac taaggaaaag
    14101 ttgtgtctgg gaaaagtgca gggaatttgg gctggcaata tacaccgcgt caatggcatc
    14161 gctttctgcc atcgcttcca gcgacgtaaa cagatgctcg acagaaaaat cattggcgaa
    14221 gtgctgggcc tgttcaaggc tgcgggaata gacggcggtt aacttgtatt taccgctctc
    14281 atgggcggcc tcgacgaact ggcgagtgat ccagttcgta ccaatcacag cgaaacgtat
    14341 cataacgcgt ggatactcca taaagggatt ctgtcgtcac tgtagcacgc cttttttatc
    14401 ttcgacgtgc gcagatacgc attattcttt tgccggacag ccatgctcac taaacggccc
    14461 aatcataacc aacggcccga gatatttcgg ctggcgatgg aggattttcg catcaatcac
    14521 cgcgctgact ctggcaagtt tttcccgcag ttgagtatat aaaccgtgct tcatattcag
    14581 gtctggcgcg ttaaaaccga tagcatcgat accatactgt tttgccagcc agatggcgcg
    14641 ttggttatga aattcttgcg agataatggt gatatggttt tcactaaaca ccttgttggc
    14701 acgcaccacc gaatcaagcg ttgagaatcc ggcatagtcg cagaagatgg cttttgccgg
    14761 tacgccttta gcgatcaagg cttgctgcat tcctgacgct tcatcgtaat ttttacgtcc
    14821 attatcgccg ctcaccaata gccatttcac ttttccggcg tggtacaact ctgcggcgct
    14881 atcaatacgt cgggtaaagt agcgattacc cggcctcgcc cccagcaata aacccacgtt
    14941 ccgcgccgga acggcgttga catcactcca ggtcagctgc ttgctggcgt tgaccataac
    15001 gcgatcggca ataaaaatgg tcgctcctgc tataagcaac aataaacagc caattttaag
    15061 agtccggcga gaaaaacaaa tacgaagaag aaggcgggca aatgcgcgca gcatggtcgt
    15121 tatccttaac gaaagggagg aggtcgattt taggcgctaa aggaggaaaa aataacgcct
    15181 gacatcattt tcagattttg tcctgcccaa gcgacaactg cgttagccac agccgggtgt
    15241 cgaactcaag ctggtggtac tgcggttcca tatgacagca caactggtaa aacgctttgt
    15301 tatgctcttt ctccttcagg tgcgccagct cgtgcaccac gatcatgcgc aaaaacggtt
    15361 ccggcgcgtt gcgaaacacg gtagcgacgc ggatctctgc ttttgctttc agcttgccgc
    15421 cctgcacacg cgaaacggca gtatgtaatc cgagcgcgtt tttcagcacg tggatcttat
    15481 tgtcatacat cactttattg atcggcgggg cattgcgcag aaactgattt ttaagatcct
    15541 gagtatattg ccagagggct ttatcggtgg cgtagtcgtg tgttcccgga taacgttttg
    15601 ccagcacatc gcccagacgc tgttcgttaa tcagcgttcg cacctgggaa agtagctgct
    15661 cgggataacc ctgaagataa gtaagattgc tcataaccgc ccacgaaaaa gagaaaaagg
    15721 gtatactcac gcaccctttt caggggcaac gtcgaaattt tatcattcag gagggccgat
    15781 gagccactta gacaacggtt tccgttcact gacactacaa cgttttccgg cgacggatga
    15841 cgttaacccg ctacaggcgt gggaagcggc ggatgaatat ttgctgcaac agttggacga
    15901 cacagagatc cgcggcctgg tgttaatcct gaatgatgct tttggtgcgt taagctgtgc
    15961 gctggcggaa cataagccct acagcattgg tgactcatac atcagtgaac tggccacgcg
    16021 cgagaattta cgcctcaacg ggattgatga gtcgagcgtg aagtttctcg acagcaccgc
    16081 cgactacccg caacagccgg gtgtggtgct gatcaaagtg ccgaaaacac tggcattgct
    16141 ggaacagcaa ctgcgtgcgc tgcgcaaagt ggtcacgcca gatacgcgta ttattgccgg
    16201 tgccaaagcc cgtgacattc acacttccac actggaactg ttcgaaaaag tgctcggtcc
    16261 gaccaccacc acgctggcat ggaagaaagc gcgcctgatt aactgcacct tcaacgaacc
    16321 gccgttggcc gatgcgccgc agaccgttag ctggaagctg gaaggtactg actggactat
    16381 ccacaaccat gcgaacgtct tctcccgcac cgggctggat attggcgcgc gcttctttat
    16441 gcaacatctg ccagagaatc tcgaaggtga gattgtcgat ctcggttgcg gtaatggcgt
    16501 tattggcctg acattgctcg ataaaaaccc gcaggcgaaa gtggtgtttg tcgatgaatc
    16561 accgatggcg gttgcttcca gccgtttgaa cgttgaaacc aacatgcccg aggcactgga
    16621 tcgctgcgag tttatgatca acaacgcgct ttccggcgtg gagcctttcc gttttaatgc
    16681 tgtgctctgc aacccgccgt ttcatcagca acatgcgctg accgataacg tcgcctggga
    16741 gatgttccac cacgcccgcc gctgcctgaa aatcaacggc gagctgtata tcgttgccaa
    16801 ccgtcacctg gattacttcc ataaactgaa gaaaattttc ggcaactgca ccaccatcgc
    16861 cacgaataat aaatttgtgg tgctgaaagc agtgaagctg gggcgtcgtc ggtaagattg
    16921 ggggttacct gccggatgcg gcgtaaacgc cttatccggc atacgttcag cacattaccc
    16981 ccaggtcgga taagacgcgg caagcgtcgc atccggcaat gtctgcccag ttctggaatc
    17041 gcgcttccat aaaacaaaaa attcctgtca ccatcctcta cattctcttg tttagcgttt
    17101 ttctacgttt attcttccgt cacacagata aattcattcg ttgccaatct gtcaacggat
    17161 gttatcatat tgccaatttg tcaacggacg tgatgaagaa tgcacctgat aactcaaaaa
    17221 gcattgaaag atgctgcgga aaaatacccg caacataaaa cggagttggt ggctctgggg
    17281 aacacgattg ctaagggata tttcaaaaaa cctgagtcat taaaagcagt attcccttct
    17341 ctggataact tcaaatatct ggataagcat tatgttttca atgtcggggc aatgaattac
    17401 gtgttgtagc aatggtcttt tttgaatcgc aaaagtgcta catacgtgaa gttatgacgc
    17461 ataaagaata cgatttcttt accgccgttc atcgtactaa ggggaaaaaa tgattgcgat
    17521 tgccgacatc ttgcaagcag gagaaaagct aactgctgtg gcaccttttc tggcgggtat
    17581 tcagaacgag gaacaataca cccaggcgct ggaactggta gatcatctgc tgctcaacga
    17641 tcctgaaaac cccttactgg atctggtgtg tgccaaaata accgcgtggg aagaatcagc
    17701 gcccgaattt gtggaattta atgccatggc tcaagccatg cctggcggta tagccgtgat
    17761 tcgtaccctt atggatcaat atggtttaac cctttccgat cttccggaaa taggcagtaa
    17821 atcgatggtg tcacgcgttt tgagcgggaa gaggaaatta acgctggaac acgctaaaaa
    17881 actggcaacg cgattcggta tttctcccgc cttgtttatt gattaacgcg acgtgccgga
    17941 tgcgtcgcat ccggcgcttc aaacaacgat ttaaatctcc agcgccagcc gtgttccctg
    18001 ggcaattgcc cgccgtgcgt ccagctccat agctacatcg cagccgccaa ttaaatgcac
    18061 ggttttccca ctatcaatca gcggttgcgc caatgcgcgg tttggctctt gccccgcgca
    18121 gatcaccaca ttgtccactg ctagtacctg cgtttcgccg ttgatcacta catgcagccc
    18181 gtcatcgtcg atcttctggt aacttacgcc tgggatcatt ttcacgccgc gcgagagcag
    18241 ggtggtgcga tggatccagc cggtggtttt gcctaaccct tgtcctggtt tgctggcttt
    18301 gcgctggagc atcacaatct gccgtgggct acgggggatt tgcatgcctt gcggactcaa
    18361 acctccggcc tgttgcaggc tactgtcgat tccccactca ttacagaacc cggcgatatt
    18421 ctggctggtg gattcgcccg gctgacttaa atacatcgcc gtatcaaaac caattccgcc
    18481 acaaccgatg atggcaactt tgttgcccac cggcgctttg tcgcgcagta catcgagata
    18541 actcaatacc ttcggatgat cgatcccgtc gataggcgga acgcgcggca cgatcccact
    18601 ggcgaggatc gtttcatcga acgcctgtaa ctgatccgct gtcactgtgt gattgagttt
    18661 tagcgtcaca cccgtcactt cgatcatccg gcggtaatag cgcagcgttt cgtaaaactc
    18721 ctctttgccg gggatctgtt tggcgatatt aaactgcccg ccgatctcgc tgtgcgcatc
    18781 aaacaatgtt acctgatgcc cacgcgccgc cgcgttaatg gcaaacgcca gcccagcagg
    18841 tcccgcaccg accaccgcca gatttttttt ctgcacggca ggaaggattg gcattttggt
    18901 ttcatggcag gcgcgaggat tcaccaggca cgaggtgact ttgccaacga agatctgatc
    18961 gagacaggcc tggttgcagc caatacaagt gttgatctca tcggctcgtc ccgattgcgc
    19021 ttttgatagc agctccgcat cagcgagaaa cggtcgcgcc atcgatacca tgtccgcatc
    19081 accgcgcgag agaatgtcgt cggcaacctg cggatcgtta atccggttgg tggtcaccag
    19141 tggcagcgaa acgtgccctt tcagtttgcg cgtgacccag ctaaatgcgc cgcgcggcac
    19201 gggcgtggcg atggtcggaa tccgcgcttc atgccagcca atgccggtgt tgataatcgt
    19261 tgcgcccgcc gcttcaatgg cctgcgccag ctctaccgtt tcggcaaaag taccgccgcc
    19321 ttcgaccaga tcgagcatcg acaaacggta gataataatg aagtcgttgc cgacgcgttc
    19381 gcgcaccgca cccactactt ctacggcaaa ccgcatccgg ttgcggtaat cgccgcccca
    19441 ctggtcacta cgctgattgg tgcgcagcgt cagaaattcg ttgatcaaat acccttcgga
    19501 ccccatcacc tctacaccgt cgtatcctgc ctcccgtgcc agttgcgcac agtgggcgaa
    19561 atcgtcgatc agttgcagga tctcttcatg ggtgagttcg tgaggaacga aacggttgat
    19621 gggggcctgc aatgcggagg gagcgaccag atgcggttgg tagctgtagc gcccggtatg
    19681 caaaatttgc agggcgattt tgccgccttc ctgatgtacg gcttcggtaa tggtgcgatg
    19741 gtgtgggatc tggttggcgt cattgagcat tgcaccgcct tccatgccaa cgcctgttaa
    19801 atctggtgcg ataccgccgc tgacaatcaa cgccacgccg tgacgggcgc gttcggcata
    19861 aaacgctgcc agccgttcag cggcgtccgg gtattcctcc agcccggtgt gcattgagcc
    19921 catcaacacg cggtttttta acgtggtaaa acctaaatcc agcggggcga acagcgacgg
    19981 gtagctcata aaattgtcca gtatgtaaaa taattgttat gtggtcggat gagttctaat
    20041 ttagccgtcg ccggagaaaa gggaaaaggg gagtgcgggg tttgtgatgg gattcaaaaa
    20101 gaatacgccc ggtggtaacg ccggatgcga cgcttgccgc gttttatccg gcctggggga
    20161 ttgctcatgt agggcggata aggcgtttac gccgcatccg ccagccgttg ctaattactg
    20221 cttacgaaaa aaatcgttat acaacatata caaatgcgcg gcactccagg agaaatttgg
    20281 tgcgccttgc tgcgcgccag tgagcgggtt gtaattctcc tgaattgggc catcggcggt
    20341 taatcctttg gcgtgccgga agaacgtatc cgccagcttc agggcatcat cacgataacc
    20401 gtaacgctcc atccctttta gaccaaacca gaactgatcc acccatacgc gcccgcgcca
    20461 gtagatatcc gcgccaaaag ccggattggt taacgccgcc gttcccagcg ggacaaaggt
    20521 gtcgaattct ttcggatcca gcatcacctt caccaccgcg tcggcattgg cctgcgttgc
    20581 cgcaccgtta aacagcggcg accagccttc cggcccttta ccgcgctcaa taatcggttt
    20641 gcccgcgcag ccgttcgcca gcggtttatc ttcaatacgc acgtcatagt agaactgtgt
    20701 agtcgggtcg aacatacaag tgttgatgta gtccgcgagc tgttgtgcta actgacgata
    20761 gcgtttggcc tcttccggct taccgagaat cgtcgccatc tccgccagat aatggttatc
    20821 gctgtacata tagctggcct gatccaccga ctcctgcaat agcgagtagc ccagcaacgt
    20881 tccgtcctta ctgcggtttt cggcgaattt caccgtccag tcgctacgtt tgccgccgtt
    20941 agcgacatat ttatccagct gttctttgtc gataaaccca aagacggcgg catcatcacg
    21001 acccgattcc cacgacgcag caacctgtgc cggaatttcc agactgtcgt actggccttt
    21061 ctccaccaca cgggcgtagt tgttcagccc agactgcgtc tcttctttgt cgcctttttt
    21121 caccgtaaac agcatctcgc cgctctcggt gttgtgggct ttgtcgcggg tcgcgccata
    21181 ttccggcacg ccgttgccgt tgtgatcgcg gttacgtaac caccagtcgt gataggccac
    21241 cagcttcggg tacatctctg ccaaccaggc cttatcctgg gtgacgttat acacttccat
    21301 tactgaccag gcggcaaggc tgggtttggt attacgttcg ttccagttgc cgccatcgcc
    21361 gccacgctcc gggctaaggt tccacgctat caggtcgggg acaaagccca catcctgtgg
    21421 acgcaccgcg tcgccaggct ggatctgcca ggagaagacc gcgcggatat tctctttggc
    21481 gatgtccgga ttgaaatgcg ccatcgcaaa cgcctgcttc caggtatccc acggccaggt
    21541 ctggttgccg gagaaccagc gcccggtcac cgacggcgtg acggtgttat atttcaccgc
    21601 accgcccggc gatcgccagt taccgttgag cgtttcgatg gctttcaccg cgacgcgcgt
    21661 ctgctccggc gtcgcatccg ggttagttaa tcctttcttc aggtattctt cccaacgttg
    21721 ctgtgaggcg gtgagataaa acgccggacg cgccagaata tcgcggatct gcatttgctc
    21781 tttgctaact tcttgagcgg tcagcagatg ggaataggtg gtatagagcg tcgtcgatcc
    21841 gttgatatgc gccttactgg taaagcgatt gccgttgatt tcagtctgca ctggcaggga
    21901 tttatgcacc tgatattctg attcaccgga ggtcagcaga tcccaggtgg cgcgcacttt
    21961 gccaaaggta actttcaggc catcgcgggt ggcgctgatt ttgcgctgat agtcagggta
    22021 ctcgccagca atggttttat cggaaagcgg tttcccttct ttcgcttcca gtttttccag
    22081 cagttcgcca tcccacacca gatccagcgg tttatcgctg gtgattttgg tttccagtag
    22141 tgatgtgcgc ggcgtggcga agcgcagaat catttcgacc tgtacatctt tcgatatcaa
    22201 cttttgcacc agcgcgccgg gaatactgta tgcctccagc gtgaaatcga ctttcttgcc
    22261 gtcctgccag acggtcaggc ggtcgaaatt gctggccata aagttgatgt actcttccgt
    22321 caacaacgca acgcctggaa agccgcccat agtgttcggg ccgtctggca acagatgacc
    22381 atgccaggct ccgagatcga aaaacggatt aaaacgctgg tgatcgtcgt aatcgtaatc
    22441 cttcatgtac tgcggcgcgc cagtacggtt aatcacgttt ttataattgt cggcgttagc
    22501 ggcatgggcg gaaaaactta tcagcagagc gcaggttact ggcgttaaaa tagttttgat
    22561 tttcatgaaa ttacagtcct tattaccagt agaaatattg catcaggaag agttggtcgc
    22621 tgggatcgtg agaggcattt ttcatgtaga agcggctatc aaaagccgtt gcgaaacgtc
    22681 cgccgccgta ttcgtaccag ataccaaact gcatgaaaga ggtggtttca tcgtcagcgt
    22741 ggtcagggcg atgtttggcg taggtgtaag cggtggagag ataaacgcct tttaacgctt
    22801 catacatggc gctcaccatc atcccgcttt cacttcccgg tacgtccagc ccgtcggcgc
    22861 gtccggtatg gtgccaggcg cgagcggcaa agttaggggt aagcaggccc gtgagataga
    22921 gttggcctgt gccgtcggtg atttccagac cgttcatcca ggtgatacct tctgtaaggt
    22981 catactggat gtaaccgttc atcattgccg gataggtgta tttgtcgtcg tagcgatcgt
    23041 acttgccaaa atgtagccag gctttgcttt cgtcatgatg tccggtaggt gtggcggtaa
    23101 cgctataacg aaagttgccg cttaagttct gtaccttcag cgcagtcata atgtcgcggg
    23161 tattgggaat gacgtagccc agatcgggcg tgaaatcgcc ccaccattgc aggtcatcca
    23221 gcgaggaatc ctgacgcaga ctgagcatga tttcggtgcc atcattggta cgataaccgc
    23281 catagaaacg gttaatccca ccttcgaagc caccccagct atggtcaggc acccaggcat
    23341 taccgtcgtg gtcggcctgt acggtccagc cttcgccgta aatcaggccg aaccaggagc
    23401 cgtacttcat ctccaggcca ccttcaatat aggtgccgtc gctgtattta tgtttattct
    23461 caccctctaa atccatatac ccaccaaccc ctaattcgcc gtaaaaacga aatgaaggag
    23521 aagatgtcga ggtcattgcg ggggtttttg agtcgtcatg ttctgccgga cgtgcttcat
    23581 cagcggccgc agaaaaggcg tagcaaaacg gcagagcaag taatgctctg catggtgcag
    23641 tgattaattt cattgtgtta atccatgagc taaagaaaaa gtacagcctt ttatcgttgt
    23701 aattataaaa atataaaggc agaaactatt ttccctctcc ccatccagga agagggaaaa
    23761 tgcctgctca ttttttatta ttctgcttaa tcaacattgc tggctggcgt cgcttcaata
    23821 tggcgctctt cagccgttaa tccctttata tatttactgt atttccacca cgcaaagccg
    23881 aggaagataa caataccgcc gacgttataa aaaatgatgg tcagaatatt cgcgccagtc
    23941 gggaatgtcg aagcgacaaa ccctacggca aatatcgcaa tcagcattga aacaacgata
    24001 ataccggtgc ggcgggagcc catacggaaa tcacgtggca ggtgatctaa tttggcacgt
    24061 aaattcaggt aagccagcat gatgaataac ggtggaagca tggacgctgc ggcggtcata
    24121 ttaataatgg tattcatcag atcctgcacg gtattggaac cgagcatcgg gataatcatc
    24181 agcgggatga cgatcaggaa ctggatccac gctgcgcgcg ccggaacgcc gttttcgttc
    24241 agttcgacgg ttttcttacc aaagatgcct tccggaattt cggagaagaa aattttcacc
    24301 ggcgttgccg tccacatcag cagggaaccg aacatcgcgg taaaggacac cagaccgaca
    24361 aagcgattca tcagtgcttc cggtagacca aaatacgccg ccatgccgtg gaatacctgt
    24421 accgatccgc cagtaaattt caactctttg ctgctgacga agacgttaat cagcaccgag
    24481 gagacggaat acagtacgcc gataaaaatc ccggcgagga tgatcacttt aacgaacgat
    24541 ttcgaaccgc ctttgacgtc gttaacgtac acagcgacgg actccgcgcc acctgcggcc
    24601 ataaagatcc aggtggtcac gccgaggaac gcccagttga agttcgggat catcgcgtca
    24661 acggtgatcg gatcggcagg ctgtacgccg ccaaccagtg ccgtacctgc cagtaaaatg
    24721 taggagagtg ttaacagcag catcagcgtt gaagtgacgg aggtaattgg ccccagcatt
    24781 ttcgccccgt tggtagaaac ccaggtggag aaggcgaaca gcaccatact gataatggtg
    24841 gtggcaaccg gcgtcataat atattcgtag ccgaggaagg catacgaagc atatgcaata
    24901 acgcgcggca acagcgaagt gaaaaagaac aggtttacga accagtaggt ataggcagta
    24961 ataaatgccc aacgtccgcc cagcgaactt tttacccacg cgtagacacc ggcttctgag
    25021 tttttattta acgaaacaaa ttctgcgatg atcagacaga agggaataaa ataaaaaatc
    25081 gtcgcgagga aaaacatcgg tgccgaggcc agtccaagct caatattatt attgataacg
    25141 ttgttaaagc tgtaaacggc ggcaaaagtc agcgagagca agccgaattt gccgattgta
    25201 ttacgtttgg tatcagacat aacacatctc cgaaaatgag tagggtagcg gtggcggcaa
    25261 actccttttg ccgccgtagt tgttatttgt tatggaaata accatcttcg atggtgactt
    25321 tgagaaccac ttttttgacc gcgttattgc agataaaccg atatgcttca tggatatcgt
    25381 aaataacgat ttgcccttcg tggacctcta cggtttctcc gcagcctttt aaatattcac
    25441 ggtcagtttc atcacgataa tattccacga cctgtaatgt ctctttcggc gcatattcaa
    25501 ttttttgctg cccttgcagg tagtaatgca cttcaaaata gcgtcgatgc ccggtaaata
    25561 gcgcatcggt cgcggagtcc gtctccacgc ggtaagtcaa tgagtcaccg atggagtggg
    25621 cgacgccagg ctgaatgttg tcgatatttt caatcgcttc aacgcagcgt tgccacttct
    25681 tgccagaggc gtaaatctgg cggaactgtt ctaagttatc gatgatcctc attgcttatt
    25741 ctcgctgtgc aaattcgtgg aaaagaaccc tgcgccgaac tcatacgacg ccaggctttg
    25801 cgcggtagct tctccgccag aaaccggcag caacgtaaag ccgtagctga agtcacggaa
    25861 ccagacgcgc caggagtcca gcacctcgct gccccaggag ttggagccga ggccaagcag
    25921 ctggtggtcg agattcaggg tgatgtcatc actgcgctgc aactcgttac agtgctgggc
    25981 agcgtggatg ttttcctggg tatagcgcca ggcgctgaag ttaatggggc gctgcggaac
    26041 caccagcaga ccattgccgt ggcggttagt cagtgccgtc cagcggacat gctgacggtt
    26101 gccgttgttc tgtgggaagg gatagttctc gaatatggca tcgacggtgc tgcgccagat
    26161 atcgatgatg ttagcctgct ggctgtcggc gtagttttcg cccggtccac gaccgtaata
    26221 cgccacctgg tcgtattcgc cgttaatccc catggtgaaa ccgatgcacg gaatgatgtg
    26281 cggatagtcg ccgtaacgct cgccggaaag cgccacgtta acctggccat cggcagcgat
    26341 gcgccagatg taggtgcagc gcatcccgaa gtcaaacacc ggtggggcaa taaccgtgcg
    26401 gctgatgatc aacacttcac catcgctctg ttctacggca aagtcgcgca gatgttcctg
    26461 catgatctgc aaatgattcg gctgccacag cccttcgtac tcctgcttgt ggttgtcgat
    26521 cattggcttg aagaagttga tttttggctc gcgggttagc agcgactcgc cattcacctg
    26581 ccaagatgtc ggtttaccac tcgtttttga gaaggtgatc gcaaagttgt agccgcgaac
    26641 agtacagctc aaacgatcgt cttccagcgt cagcggacgg gcgttattcg gtgcgaaagg
    26701 tacaggctgc gcggtgtttt ccttcagcgg gaactgataa gtggcgatag aatgcccggc
    26761 ttcgctgtag cgggtgcggg aatctttggt caccgtaatg ttgagaaacg cttcgcgggc
    26821 gtccagctgt ggcagcgtga tctgtaaggg ggcttcgctg ttcggcgcaa cgtcgcgcag
    26881 tttaatctgt tgcgtcgcga gcgtttcacc ttcggcgcgc acctctgcgt gcagggtgta
    26941 gtcatcaagc gtggtaaacc acagtttatt ttcgactttc agttcgccgc gagtcagatc
    27001 cagcgcgtgg atttttaccg gcgcaataac ctgtttgtac tctttcaggc ccggtcccgg
    27061 cgtctgatcg gaatagatca aaccatcaag acagaagtta tagttgttgg gatagtcgcc
    27121 gtagtcgccg ccgaatttat accagacatt gccgttgtca tcctgcgcct ggatcccgtg
    27181 gtcgcaccat tcccagacat aatgtccctg aatgcaatcg tgcttataga agacgttctg
    27241 gtactccgtc agccctcccg gtccgttccc catcgcatga gcatattcac agatgatgcg
    27301 cggcttcgga tgcgggtatt caccaaactc attcatcagc ggcacgcggg tgtacatggt
    27361 ggaaataata tcgaccactt cagcatcgcg atcttcttcg taatgcacca gtcgcgtgtc
    27421 atccagcgcc ttcgccgcat ggtacatcgc gcggatgtta cagccatagc cggattcatt
    27481 gcccagcgac cagatgatga tcgacggatg gtttttctgc gcgtgaatat ggcgaacaat
    27541 acgctcgacg tagacttttt cccactgcgg atcgtcggta atacggctga tatcgccgac
    27601 attagcaaag ccgtgcgatt cgacgtcggt ttccgccatc acaaacaggc cgtagatatc
    27661 acacagttcg taaaaacgcg gatcgttcgg gtagtgagcg gtacgcacgg agttgatgtt
    27721 gtgctgcttc atcaactgga gatctttctc gacgcgatcc attccaacgg cgcggccttt
    27781 gcgatgatcg ttgtcgtgac ggttgacgcc gtgcagcatc acataacggt tattgatcca
    27841 gaacagaccg tcgcgcactt tgatatcacg gaagccaacg cgttgtggca ccacttccag
    27901 aacgttgccg tcggcgtctt tcagcgtcat gaccaaatgg taaagataag gggattctgc
    27961 tgaccattgc tggggctgtt cgacagtaaa agcaaagctg gcgctggtca gtttttcaat
    28021 tgccaaatga tcaatggcgc tgctgtgcac cacgagttcc ccatcaaaca gggtatattc
    28081 cagcgtcgtt acgacagggg aggcggcgag attttccagc accacttcgc aggaaagcgt
    28141 ggcatcgcaa taggcttcgt caaagtcggt gcgcacggtg aaatcgttaa tatgcgtgag
    28201 ttgttttccg atcagataaa catcgcggaa aatccccgcc gaccaccaca tatcctggtc
    28261 ttccacgtag gtagagtccg cccactgcat cacgcgcaca cacaacaggt tgtcgccggt
    28321 tttaaccatc gcgctgatgt caaactctgc ggtcaggcga ctgcccttgc tgaaacccac
    28381 atactgaccg ttaacgtaga cttcaaaata ggtttcgacg ccgtcaaatt taatcagcgt
    28441 ctgtttaccc tgccagccgt cgctgagggt gaaaatacgt tgataggcac cggttgggtt
    28501 atcgctgggg acaaacggca catcgatagg gaacggaaaa ccttcgtcgg tatattgcag
    28561 tttgccgtga ccttccattt gccacatggc ggggacggta atatgccccc agtcagccat
    28621 taactcagag gtgaaggctt ctggcacttg cagcggatgg tcaaaaaagt ggaaattcca
    28681 ctgaccgctt aagggcagaa acaggctgct cgtttcgcgg gcaaaggtac gcgcctgcgc
    28741 aacagaatca tatgaaaaaa agtacgcacg cggcgcaagt cggttttcgt gggtgagctg
    28801 aatgttttcc cagcgattca tagggcctcc cggtagagag aaatcggaac catttatggt
    28861 gatggtagtt tgtgtaattg ctggggagtt tagtaaaatt tttactaaaa agtagcaggt
    28921 aaatgcattt actttaactg gatcacgaaa ataaacggca gcactgtccg gcaaaaacga
    28981 ttgccggaca gtgtgtaagg ggatttaacg ggtcgtgccg cgcagtttta atttgctggg
    29041 aacgaagatc aacagcggca gcgcgcgacc atcgcgggct ttttcataca ccaggttaac
    29101 gccctgactt cccatcatct cggaatggat gcgcacggtg gagagcggcg gaaaggtaaa
    29161 tcgcgcggtg gggatatcgt taacgctgat gagcgaaata tcctgtggga tgttcaggcc
    29221 acgttcatga attgcccgca gtacgccgat agcaatggaa tcggaagcaa caaacagtgc
    29281 cttcggatag tcttcccgcg ccagcatctg ttttgccagt tcatagcccg atgaactgga
    29341 aaaaccgccg cgccagatat cctcttcgcg taccacgtgt ttcagtcggc catattccac
    29401 aaaggcgacc tcacgaatat ccgccttgcc aggcaagtct tcaccgccaa taaaaccaat
    29461 acgattaacg ccctgatcga tatagaaatc gatgatttct ttactgatac gtgccagatc
    29521 gatatccacc gcatcgtaac cgctgccggg ttcgtgaaag tcgataaagc agatattgtc
    29581 ggtcaacgca caggcggcgg cgcgcagggc gggcgtgggt ttgccgacaa ttaaaatacc
    29641 ggtgacgttt ttaatgtctg gtaagccgtt gtgttcataa cagttggtca gttcgatcgc
    29701 cagcttttcg cactgagttt caatgccgtg gcggatcgcc agatagtaag gatcgttgat
    29761 ctccagctcc tgttggtagc tgtagatagc caaaatatgg tgttggttga ctgcgcctgt
    29821 ctggagttta cgggcgctac tggtcttgta ctccagcttt tcggcgatct cgagaatgcg
    29881 atgtttcgtc tcttctttca cattcaatgt cggatcgtca ttcaagaccc tggatactgt
    29941 cgccagggat acgccagctt cgattgcgat gtcttttagt gttgccatgt ttaccttttt
    30001 tactttccct gatgtgcgcc cccattgtag aggaagtgct tatcgggtca cctgttttca
    30061 gtaaataaag cgcgtttctt tgacgctgta acggtaacac agcggctcac gaatgtgatc
    30121 acgcctgcat tctccagttt tagcctacag gattgagaaa aacttttgct ataatttagt
    30181 aaaattttac ccgaagagag gaaacaatgg aaaccgtggc ttacgctgat tttgcacgtc
    30241 tggaaatgcg tgtcggaaag attgtggaag tgaaacgcca tgaaaacgcc gacaagctgt
    30301 acatcgtaca ggttgatgtg ggtgaaaaaa cgctgcaaac cgtgaccagt ctggtgccgt
    30361 actacagcga agaagagctg atggggaaaa cggtggtggt cttatgcaat ctgcaaaaag
    30421 cgaaaatgcg cggtgaaacg tcggaatgca tgctgttgtg tgcggaaacc gatgacggca
    30481 gtgaaagcgt gctgttaacg ccggagcgga tgatgcctgc gggcgtacgt atcgtataaa
    30541 aagatcggat ggcgacgtcg aatcgccatc cgatttgata ctacgcttct tcgacactga
    30601 ctcgcatggc cgccagcgcc ttacgtgccg ctttgatcac ctgttcacac tgttcaatgg
    30661 tcagtgtcag tggcggttca atgcggatcg ttttggcgtt attgagcgtt ccggccacca
    30721 ggacgcgctg gcggaacatc tcgctggcaa agttatagcc gatttcgtta tcaacaaact
    30781 caatcgccat caacatccct ttgccacgcg cttcctgtac cagatcggga tattcccgcg
    30841 ccagttgacg gaaaccgtcc agcaacatat cgcctttttg ttcagcctga gccggtaagt
    30901 tctgctccag caacacattg atggtcgcca gcgccgccgc acaggccagc gggttgccgc
    30961 caaaggtggt ggtatgcagg aacgggttgt cgaacagcac ggagaacacc tcttcagtgg
    31021 cgatggttgc gccaatcggc atcacgccgc cgccgagggc ttttgccaga cacaggatgt
    31081 ccggctgtac gttctcatgc tcgcaggcga acatcttgcc cgtgcgcccc ataccggttt
    31141 gcacttcatc gaggatcatc agtgcgccga actcatcgca cagcttacgc acggcggtga
    31201 gatagcccgg cggcggcaga atgacgccac cttcgccctg aatcggttcg aggatcactg
    31261 cagccacatc atcaccggtt tttttgcact cgctaagggc cgtgcgcatg gcttcgatat
    31321 tgccaaacgg tacatgacgg aaccctggca gcagcggcat aaatggtttg cggaaggtcg
    31381 atttcgccgt ggccgacagc gcgccaagtg atttaccgtg gaacgcgccg ctggtggcaa
    31441 taaaagtaaa cttgccgcgc ggtgactgat aagccttcgc cagcttcagc gctgcttcaa
    31501 cggactcggt gccgctatta cagaagaagc tgtatttcag tttaccgggc gttagcgccg
    31561 caagggtttt cgccagaatc gcccgtaacg gatcgagcag ctcctggctg tgcagcggtt
    31621 gtttcgcaag ttgattctgt acggcggaaa ccacaactgg attacggtgc cccacgttga
    31681 aaattccaaa acctccaagg cagtcgataa actcctgtcc ctgggtgtcg acaagcgtat
    31741 ttaaacctcc cgcttgccac tctacggctc cgtaatcccc gccggcggta acagatttgc
    31801 gatactctaa aaaccccgga ttgacatgct ctttgaagta ttcaatcacc tcccggttaa
    31861 gtgctttcat ctcctcatga tccaacgttc gcttttcaat gagattcagg gcgtgggcgc
    31921 tgcacgctaa agctgatgcg ctcgaaggta acctgttcaa aatatgctcc ggaggctcgc
    31981 gtatcacatg ataccgattt aagtattgca gggattgcgc cactccggct gcgatcgcga
    32041 aaatcgggat aaacacaaat gtggttatca tttgcgcaat atttaatgct atttgctaac
    32101 atttgctgtt attttgcacg gtttttgtcg ggtatggatt tgatgattgc tgcgcaaatg
    32161 cacgctttca gggcaataat tgcctgattt ttgggcaaga taattaacgt tttcgtatag
    32221 taacagagtg aaagtatttt aaatcaagga attagatttg tgctttagtc gcaaattgcg
    32281 atctaaatca aattaattgg ttaaagataa ccgcagcggg gccgacataa actctgacaa
    32341 gaagttaaca accatataac ctgcacagga cgcgaacatg tcttctcatc cgtatgtcac
    32401 ccagcaaaat accccgctgg cggacgacac cactctgatg tccactaccg atctgcaaag
    32461 ctatatcact catgctaatg acacttttgt gcaggtgagc ggctatacct tgcaggagtt
    32521 acaggggcaa ccgcacaaca tggtgcgtca cccggatatg ccaaaagcgg cgtttgcgga
    32581 tatgtggttc accctgaaaa aaggggagcc ctggagcggc atcgtgaaaa atcgccgcaa
    32641 aaatggcgac cattattggg tgcgggccaa tgcggtaccg atggtgcgcg agggaaaaat
    32701 cagtggctat atgtcgattc gtacccgggc gacggatgaa gagatcgcgg cggtggagcc
    32761 gctgtacaaa gcgttgaacg ccggacggac cagtaagcgt attcataaag gcctggtggt
    32821 gcgtaaaggt tggttgggaa aactgccttc attaccgctt cgctggcggg cgcgtggcgt
    32881 gatgaccctg atgtttatct tgctggcggc catgctttgg tttgttgctg ccccggtggt
    32941 gacgtatatc ctctgtgcgt tagtggtatt gttggcaagc gcttgttttg aatggcagat
    33001 tgtgcgcccg atagaaaatg tcgcccgtca ggcgctgaag gtggcgaccg gagagcgtaa
    33061 tagtgttgag catctgaatc gcagcgatga gctggggctg acattacgcg cggtagggca
    33121 gcttggtctg atgtgccgtt ggctaattaa cgatgtctca agccaggtgt ccagtgtcag
    33181 aaatggcagt gagacgctgg cgaaaggcac cgatgaactg aacgaacata cccagcagac
    33241 agttgataac gttcagcaaa cggtggcgac catgaaccaa atggcggcgt cggtgaaaca
    33301 gaactctgcc acggcgtcgg ctgccgataa actttctatc actgccagta atgcggcagt
    33361 gcagggcgga gaggcgatga ctacggtgat caagacaatg gacgatattg ccgacagtac
    33421 ccagcgcatt ggcaccatta cttcgctgat taacgatatt gcgtttcaga ccaatattct
    33481 ggccctgaat gcggcggtgg aagcggcgcg tgccggcgaa cagggcaaag gttttgcagt
    33541 ggtggcgggg gaagtgcgtc atttagccag ccgcagcgcc aatgctgcca acgatattcg
    33601 caagctgatt gatgccagtg ctgataaggt gcaatccggt tcgcagcagg tacacgccgc
    33661 cggacggacg atggaagata ttgtggcaca ggtaaaaaac gtcacccagt tgatagctca
    33721 gattagccat tcaacgctgg aacaggccga tgggctttcc agcctgaccc gtgcagtgga
    33781 tgagcttaac ctgatcaccc agaaaaacgc cgagttagtg gaagagagtg cgcaggtgtc
    33841 ggcgatggtg aaacaccgcg ccagccgact ggaagacgcg gtgacggtgc tgcattaatc
    33901 ggtatgccgg atccggcggt tggagcacaa tgcctgatgc gatgctggcg catcttatca
    33961 ggcctacggg gggggtaggg tacgccgcat ccgttaatcc agttgggtaa tatcaaaagc
    34021 ggcgcggtcg atcaccgcaa tgatcttttt tatttgtgca tcagtgatat cgctctggtt
    34081 gacgcgtaaa tccagcaccg ctttaaaatt atccagcgcc cgcttcattt gcgggttctg
    34141 gcgcagcgct gcgccaacgc aacgcgcttt gatgcgttct tcaatcatct ccacctgttc
    34201 gcggttttct tccagccact gcgagccttg ttcggtcaac gcaatctgct tcttaccacc
    34261 ttcctcttcg cggatggtaa tcagcgactg ctcctgcaga aaatccagcg tcgggtagat
    34321 gacgcccggg cttggggtgt aattcccctg ggtcagattt tcaatcgctt taatcaactc
    34381 gtaaccgtgg ctgtcatcgc gcgagagaat atccagaatc accagacgca attcaccgtg
    34441 accaaagaaa cgctgccgac gaccgccgcc gcgaccgtgg cgaccaccgc agcattgacc
    34501 gtgttcatgc tggtgaccgt gtccgcagtg ctcatgttct gacttctcac ctttgcagca
    34561 gccctcatgg cgtggctggc cttcatgttt acaacaccct tcgtgatgat ggctcatatc
    34621 agcctccttt tgcttaatta gatatatcta atttatatct gatatgagca ctcttgcaag
    34681 aataaaaatg atttttaaac gtggactcat ctcacacgta ggccggataa ggcgttcacg
    34741 ccgcatccgg cgttgagtaa tgatgcctga gaagaggcgg ttcgtcttat cagactatag
    34801 acatatcagt tctacaaatc gcttgcattt atcatgatta acaatcatta tcatttacga
    34861 aaattattta gatatatctg attaccatca cgaaggcgat aacaatgaat aactcccccc
    34921 gctacccgca gcgcgttcgc aatgatctgc gcttccgtga actgactgtg ttacgcgttg
    34981 agcgtattag cgtcggtttt cagcgcattg tccttggcgg cgaggctctg gacggtttta
    35041 catcgcgcgg ctttgacgat cacagcaaac tcttctttcc tcaatctgat gctcactttg
    35101 tgccgccaac agtaacggaa gagggcatcg tctggccgga aggaccacgc ccaccgtcgc
    35161 gtgactatac gccgctgtat gacgaactac gccatgaact ggcgatcgat ttctttattc
    35221 acgacgatgg ggtcgccagc ggctgggcga tgcaggcgca accgggcgat aaacttacgg
    35281 tggcagggcc gcgcggttcg ctggtggtgc cggaagatta cgcgtatcag gtgtatgttt
    35341 gcgatgagtc cggaatgccg gcactgcgcc gccgcctgga aacgttgagt aaacttgccg
    35401 ttaaaccgca agttagtgcg ctggttagcg tgcgggataa cgcctgtcag gattatctcg
    35461 cgcaccttga tggttttaat atcgaatggc tggcacatga tgagcaggcg gtagatgcgc
    35521 gtctggcgca gatgcaaatc cctgccgatg attacttcat ctggataacc ggcgaaggca
    35581 aagtcgttaa gaatttaagc cgccgctttg aagcggaaca gtatgaccca cagcgggtac
    35641 gtgcagcggc ttactggcac gcaaagtaac tgatatatat aaagaaaaag gctgacgatt
    35701 tctcgtcagc ctttgctata tctggtggcc cctgctggac ttgaaccagc gaccaagcga
    35761 ttatgagtcg cctgctctaa ccactgagct aaggggccat ggtagcggat tataaagtaa
    35821 ctccgtgtcg caatccagcc attaccgcgc gcctgctgtt tttataaaca atgtattttc
    35881 aatccgttat acttttcctg gtgatgttag aaaggagtaa atatggttga ggatattttg
    35941 gctccagggt tacgggtcgt gttttgcggt atcaaccctg ggctttcatc cgccggaacg
    36001 ggttttccct ttgctcatcc ggcaaatcgc ttctggaagg tgatatatca ggccgggttt
    36061 accgaccgtc agttgaagcc gcaggaggca cagcatctgc tggattatcg ttgtggcgtc
    36121 accaaactgg tagaccgtcc aacggtgcaa gccaatgaag tttcaaagca ggagctacac
    36181 gcaggcgggc gtaagctaat tgaaaaaata gaagattatc agccgcaggc gttggcgatt
    36241 ctgggcaaac aagcatatga acagggattc agccagcgcg gtgcacagtg ggggaaacaa
    36301 acgctcacca ttggttcgac gcagatttgg gtgctgccaa atcccagcgg tttaagtcgc
    36361 gtttcactgg agaaactggt tgaagcgtat cgcgagttgg accaggcgct ggtagtgcgt
    36421 gggcgataaa aaacgccacc gaaaaggtgg cgtttgtgca gagggactag tgccgggtgc
    36481 ggcgtaacgc ctgatccggc ctaccgatta atcgtccagg aagctacgca gcacttcaga
    36541 acggctcggg tgacgcagtt tgcgcagcgc cttcgcttcg atctgacgga tacgttcgcg
    36601 ggtaacgtcg aactgtttac ccacttcttc cagcgtgtgg tcggtgttca tatcgatacc
    36661 gaaacgcata cgcagaactt tcgcttcacg cgcggtcagg ccagccagca cgtcgtgcgt
    36721 tgccgcacgc aggctttcgg tggtcgcaga atccagcggc agctcgaggg tggtatcctc
    36781 gatgaaatcc cccagatgcg aatcttcatc atcaccgatc ggcgtttcca tggagattgg
    36841 ctctttggcg atcttcagca ctttgcggat cttgtcttcc ggcatcagca tacgttcagc
    36901 cagttcttcc ggcgtcggtt cacggcccat ctcttgcagc atctggcgag aaatacggtt
    36961 gagtttgttg atagtctcaa tcatatgcac cggaatacgg atggtgcgcg cctgatccgc
    37021 gatagaacgg gtgatcgcct gacggatcca ccaggttgcg taggtggaga acttgtaacc
    37081 acggcggtat tcgaatttat caaccgcttt catcaggccg atgttacctt cctgaatcag
    37141 gtcaaggaac tgcaagccac ggttggtgta tttcttggcg atagaaataa ccagacgtaa
    37201 gttcgcttca accatctctt tcttcgcacg gcgggctttc gcttcaccga tggacatacg
    37261 acggttgata tctttaacct gctcgatggt caggccggtt tcttcttcaa tctgctgcag
    37321 tttctgcagg gcgcgatgca cttcttcaga gacatcgtgc agtttttccg accacggctt
    37381 gttcatcgca attgccgcgt tgaaccaggt atcgctggtt tcgttgccgg taaacagggt
    37441 aatgaagttt ttcttcggca ttttgcactg ctcaacgcag agcttcatga tcagacgttc
    37501 ttgcgtacga acgcggtcca tcatgacgcg catgctgttg accaggtagt caaactgctt
    37561 tggcaccagg cggaactgtt tgaatacttc agacagtttc aggatctctt cctgagcggc
    37621 agcgtgactg cgacctttcg ctttgatggt gtcacgcgtt acaacgtact gagcgcgcag
    37681 ttccgcaaat ttttcgcgag ccagttccgg gtcgatgctg ttgtcatcat cggcgctgtc
    37741 gtcatcgcca tcttcttcgt cttcatcttc gtcatcgtcc agatcttcct gggaaagctc
    37801 agaaccgacg tgagtggcgg taggtgccag atcttcttct gcgttcgggt caacaaagcc
    37861 ggtgatcaga tcggacagac gcgcttcttc tgcttcaaca cgatcgtact gttccagcag
    37921 ataggtgatc gcttccggat attcagcaac ggagcattga acctggttga tcccgtcttc
    37981 aatacgctta gcgatgtcaa tttcgccttc gcgggtcaac agttcaacgg tgcccatttc
    38041 acgcatgtac atgcgtaccg ggtcagtcgt gcgcccgatt tcagattcca cgctggaaag
    38101 cacctgcgcg gcggcttcgg cagcatcttc gtccgcggtg ttttcagcca gcatcagatc
    38161 atcggcatcc ggtgcttctt ccatcacctg aatgcccatg tcgttgatca tttggatgat
    38221 gtcttcgatc tgatctgaat cgacgatatc ttccggcaga tggtcattga cctcggcata
    38281 ggtcagatag ccttgctcct taccacgggt gacaagaagt ttcagctgtg actgcgggtt
    38341 ttgctccata agacggtatc cacacttatt tcatgaggtt ggtgttgggc gattgacccg
    38401 atgtccttca gccgttaacg ctgaaatcca acggttgttt accgccaacg ataattacga
    38461 gggcgtactt atatatttgc cgctgcctct cagtgcggct gtcgggggct tcccgatcgc
    38521 tcttcggcac ttaagccgtt aaatcacttt ttcgccagct cctggtttaa tgtccagagc
    38581 tccaggcgtt cttcgttgct taaaccatgc gtgcgctcac gagcgattaa ctcttcctgg
    38641 cgcagttcaa gcagcgaatc aaacatatgg ttgagtgagt cggtgaaggt ttgctcagca
    38701 atattcttat ctgctatatc gtcccacatc gacagttttt caagggtggc agcattattt
    38761 gtaccacgat agtgctctaa aagttgcccg gtggtcagac ctggctggga gagacaagtg
    38821 ttgaccagtt ctctgaataa gccaagtcca gggagcttat tttcatccag attctcaagc
    38881 ggcgggacca acgtcgctaa ttctggattt tgcaccagca accctataag tatacgcatg
    38941 gtcgtgcgtt ttagctgcgg aacagggcga gaaacgccgc tctctgccgc ttttggcatt
    39001 aatcgttcaa gctggctgtc atcaagtatg cctaatttgt tgcctaattc ctgacgaaga
    39061 tatattcgca gcgtttcgcc cggcacttgc gatatcagtg gcagtgccag cgtactcaaa
    39121 cgtgcgcgcc cgtcaggggt actcagatca acttgcggca tcagactgtt aaacagaaat
    39181 gcggagagtg gcatcgcctg ctccatccgc gcttcaaacg cttctttacc ttcttttcgt
    39241 accagcgtgt cagggtcttc gccatcaggc aaaaacataa agcgtagctg acgaccgtct
    39301 gtcatgtaag gcagcgccgt ttccagcgct cgccaggcgg catcgcggcc tgcacggtcg
    39361 ccgtcataac agcaaatgac attgttggtc gcgcggaaca acagttgtat gtgatcggcg
    39421 gtggttgacg tacctaacga cgcaacggcg taattaatgc cgtattgcgc cagcgccacc
    39481 acgtccatat agccttcgac cacaagcaga cgattgggtt cagcgttatc ctgctgcgct
    39541 tcataaagac cgtaaagctg gcggccttta tggaaaatgt ccgtttccgg cgagttcagg
    39601 tatttggggg tatcgttgcc cagcacgcgt ccgccaaaac caatcacccg accgcgttta
    39661 tcacgaatgg ggaacatcac ccgctcgcgg aaacggtcgt aactgcgccc ctgatcgtta
    39721 gtgaccaaca tgcccgcatc aatcaatgac tggcgatttt ctggattgcc gccaaaccgc
    39781 ttcaggacgt tgtcccagcc agggggggca aaaccaatcg caaagcgggc gataacctcg
    39841 tggcttaatc cgcgtttttc cagatactgg cgcgcagacg tggcaacagg ttgctgtaaa
    39901 gattgttggt aaaacgtatt cagaccgtcc atcaactgat aaagcgtttg tcgttgatgg
    39961 cgctcgatct ggctggggcc gctacctgct tcaaatggca cttcaagatt gtgcattgct
    40021 gccagctctt cgaccgtttc gacgaactca agcttgtcgt agttcatcag gaagtcgatc
    40081 gcgttgccgt gcgcgccaca tccaaagcag tggtaaaact gtttctcacc gttaacggtg
    40141 aatgatgggg ttttctcgtt gtggaatgga caacacgcgt ggaaattctt gccctgcttt
    40201 ttcagcttca cacgggcatc gatcagatcg acgatgtcag tgcgtgccag cagatcatta
    40261 atgaatacgc gtgggattcg tccagccata ggccccgatt tttagcaatt cataaacgaa
    40321 aataagccgc gcattccttt cggaagcacg gccttacaac tacaactcgg tctgatcgga
    40381 gagcaacgct ctcggggaat tagtacagac gagtgcggcg tgcgttttcg cgagccagtt
    40441 tcttcgcgtg acgtttcact gcagaagctt tagcgcgctt acgttcggta gtcggttttt
    40501 catagaactc acgacgacga acttccgcca gaacacctgc tttttcgcag gaacgcttga
    40561 agcgacgcag agctacgtcg aacggctcgt tttcacgtac tttaattacc ggcatgtgcc
    40621 tctcaccttt gattaattcg gtttgccgct ggcatcaacg ccagcttatt tcaaaatggt
    40681 gcggaatttt actgcaattg ctgctgcttt gtaaagcacc gcggcctttt ttgaaaggga
    40741 cttttataag ggtgaggagt atacacgagg ctttctccag gggcgaacaa agttttacat
    40801 caacccgcat tggtcctaca ctgcgcggta ataaagcgag gtaaaacaag tcatgcgtgt
    40861 actgggtatt gaaacttcct gcgatgaaac cggcatcgcc atttacgacg atgaaaaagg
    40921 tttgttagcc aaccaattgt atagtcaggt gaaattgcac gctgactacg gcggcgtcgt
    40981 gcctgaactg gcctcccgcg atcacgtgcg taaaaccgta ccgttgatcc aggaggcgct
    41041 gaaagagtct ggtttaacgg caaaagacat tgatgctgtg gcctataccg caggcccagg
    41101 attagtcggc gcactgctgg ttggcgcgac cgtggggcgt tctctggcgt ttgcctggga
    41161 cgttccggca atcccggtac atcatatgga aggacatctg ttagcgccga tgctggaaga
    41221 taacccaccg gaatttccgt ttgtcgcgct gctggtttcc ggcggtcata cgcagttaat
    41281 cagcgtgact ggcattggtc agtacgagct gctcggtgag tctattgatg atgccgccgg
    41341 tgaagcgttt gataaaaccg cgaagctgct ggggctggat tatcctggcg gaccgttact
    41401 gtcgaaaatg gcggctcagg gtactgccgg gcgctttgtc ttcccgcgcc cgatgaccga
    41461 ccgtccgggg ctggatttca gcttttctgg tctgaaaacc tttgcggcga acacgattcg
    41521 tgacaacggc accgacgacc agacgcgtgc tgatatcgcc cgcgcctttg aagatgcggt
    41581 ggtcgatacg ttgatgatta agtgtaagcg agcactggat cagacgggct ttaagcgact
    41641 ggtaatggca ggcggcgtga gtgctaaccg cacgttacgg gcgaagctgg ctgaaatgat
    41701 gaaaaaacgc cgtggcgaag tgttctacgc gcgtccggaa ttttgtactg ataacggcgc
    41761 gatgatcgcc tatgccggaa tggtgcggtt taaagcaggc gcgacggcgg atctcggcgt
    41821 tagcgtgcgt ccgcgctggc cgctggcgga gttaccggcc gcgtaaaact attgggtgcc
    41881 ggagagtcac ttccggcacc gtcctcactt aaagcaacac cacgggcatc cacagtaagc
    41941 cggtaatcac cagcaatacg aggaatatca gcccaaaaat tgcccccagt cgccagtaat
    42001 ccaccgttgg cagataacca ctaccgtagt aaatcgggct gggtccggtg gcgtatggcg
    42061 taagaatgct ccccagacca attgccgcgc caaccatcag gcagaatacc ggcagcggga
    42121 tttccggcat cgccagcgcg gcggcaatca tcatcggcgc gagagcggag gtatacgccg
    42181 tggcgctggc gaaaaagtag cgcagtagat aaaacaccac aatcaacgcc accatcacta
    42241 tcgttggcga ataaccgctt aagctgcctg ctaacagttt gccaaaccag ctaataaaac
    42301 cggtgttgtt gagtccggta gcgagggtga taagcgaggc cagccagaag aaaacgttcc
    42361 acgcggcttt attactgaca atgtcgtccc aactgataat gcgcagaagc agcatcagcg
    42421 ccaccacgct gtaaccgacc atcgcggcat cgatataatc accgccgaaa atccacagca
    42481 ccagcgcgcc taccatcagc cccaacatcc gtttttcacg cgaacagagc gggcccattg
    42541 cctgcagttc cgtctctgcc cagcgcggca cctgatcacc agacttcagt accggcgggt
    42601 acagcacgta agccagccag ggaaccagca gaaccagtaa aatactgagc ggcaacatcc
    42661 cgaggaacca gtcgccccaa ctcagtgtgg cgtgagatgc gcttttcatc aggccaatta
    42721 acagcaagtt aggtgccatc gccgtcagga aaatggcgct ggtcacgcag tcggcaacaa
    42781 tccccatcca catgatgtac gagccaatgc tgcgcgaact gctgtcgttt ggttgtgatt
    42841 gatagagcgg tggcaggtta cggatgatgg gaaagataat tcccgcacca cgcgccgagt
    42901 tggacggtgt tacaggcgcg agtatcagct cggagaacat cactgcatag ccgagaaaca
    42961 gcgtgcgatg ccccattttt ttcaccagaa tcagcgcaat gcggcgtcca agcccggttt
    43021 tttcatagcc tgtgccaaac ataaaggcgg cgaaaatcag ccagataacc gaattagaaa
    43081 aaccagaaac cgcccaggag agggatttgg cggtgaactt aaaacctggc tgggcgagct
    43141 gctccgggct aaacagcagc cacggcgaaa gaatggcgat gatggagata cccaccatcg
    43201 ccaccacggc acccggcacg ggttcgagga tcagtccaac gatcacgcca gtaaaaacgg
    43261 caaagtagag ccaggtatga ctctccagcc ctgcgggaag cggaagtaga gcaataatgg
    43321 cgatgaccgc cagcggcgca aggtatcgcc accattcagt ggaaggtttc atcgtgttat
    43381 gcctgcgaaa aaggagaggg ggtgagcctc tccgggaggg ttatttgatg tagtggacgt
    43441 gctcgcaaat ctcttccacg atgggatcgc ggcgttcggc gaacagcttt ttgttttcgg
    43501 ctatcaggtt gttgccgtgg gtatcaatag agacaatcag cgggccgaac tctttgaccc
    43561 ggcagaccca cagtgactcc ggcatcccga gttctgtcca gtgcacctct tcaatctctt
    43621 ccacctgggt tgccgccagt actgcgcagc ctgccgggaa aatcacatgc agcgccttga
    43681 atttctggca gccttcttcg gtcagcggcc ccattccgcc tttgccgacc accagtttca
    43741 cgccggtctg ctcgataaat tcacgttcaa aactttccat acgcatactg gttgtcgggc
    43801 cgacggacac catctcccat ttgtcgccgt ttttgcgcac gatggggcca gcgtggaaaa
    43861 tcgctttgcc gttgagatcg taagggatcg gacgtttgag ttcgatcaag cgacggtgac
    43921 aaacgtcacg gcaggtcacc agcgtaccgg tcaggtagat cacatcgccg acgcgaatat
    43981 cttgcagatc ttcagctttg atcggggttg tcaggatctt tttcataacg cgctccgggt
    44041 gtgagacaga ttttcaaagg tgagatcggc atgaaccagc agtgtgccgc gacgatgcgc
    44101 ccagcagcct gtagaaacag caacgccgat ggttgacgga tggcgggcgg cagattcgat
    44161 atgtacgccc atcactgaac tgttgccagt cagcccttgt ggaccaatcc ccagacggtt
    44221 gagtccttct tccaggcgta gctccagctc tgccgctttc ggattggggt ggcggctgcc
    44281 aatcgggcgc aaaatggctt ttcgcgagag cactgcggcg gtttccaccg aggtggcgat
    44341 gcccacgccc accagtaccg gtggacaggc gtttacggcg agggtggaga tattttcgaa
    44401 gacgaatttc actacgcctt cgtagccttc tgacggcatt aacactttcg agcggcctgg
    44461 tagcgtgcag ccgccgcctg ccatgtaaac ttcgatttcc gcatcgtcat tgtcggggat
    44521 gatgtcccag gtgacccacg gtacgccgct accggtattt ttgccggtat ttacttcgtc
    44581 aaaaatttct accgcattgt gacgcagtgg cgctttgacg gttgcctctt ccacggcttg
    44641 tttgagtatg ctttgcagct cgccaagcag tgggaagcgg gaaccgactt taacgaagaa
    44701 cataatctcc ccggtgtcct gacaggccgg gcgattcagg tcgattgctt tttgcatgtt
    44761 gtcgaacatc gtgtggtaga tgattttccc catcgacgac gtttcggcat cctttagctg
    44821 ttttagttta tccaccacgt catcgggcat tcgggtagaa atcatggcgg taaagttagc
    44881 gacaatctcc gtcaacttat tcactgcctg ttgcttatta ctttcgctca tcatggcaac
    44941 tccagtttat gtatttgtct ggaaaaattc accgccacaa actaccacta aaaatgtggt
    45001 tttatatttt ttgccgccgt gaatatgtaa ttcacagttc gtgaatcaac gcgaaaataa
    45061 gaatgaatat tgcgccagag cagggaatgg caatgttttg cgaaatacac tgcgcttatc
    45121 acaactgcgg ataattaacg atgctgaata gctggccttt agccaaagat ttgcaggtac
    45181 tggtagaaat cgtccacagc gggagtttta gtgctgcagc ggcgacgctt gggcagacgc
    45241 ctgcatttgt caccaagcgg atccaaatcc ttgaaaatac gctggcaaca acgctgctga
    45301 accgctccgc tcgcggtgtg gcgctgactg aaagtggcca acgttgttac gagcatgcgc
    45361 tggaaatcct cacccaatat cagcgactgg tcgatgacgt cacgcaaatc aaaacgcgcc
    45421 cggaggggat gattcgtatt ggttgcagtt ttggttttgg gcgcagccat attgcgccag
    45481 ccattaccga actgatgcgc aattatcctg agttacaggt gcattttgaa ttgttcgatc
    45541 ggcaaattga tttagtgcag gataatattg atctggatat tcgtattaat gacgaaattc
    45601 ctgattatta tattgcgcat ctgttaacga aaaataaaag aatattatgc gcagcacctg
    45661 agtatctgca aaaatatccg cagccacaat ccttacagga attaagtcgt catgattgtc
    45721 tggtgaccaa agagcgcgat atgacccacg gaatatggga gttggggaac ggtcaggaga
    45781 aaaaatcggt gaaggtaagc gggcatcttt cctccaatag cggcgagata gtgttgcaat
    45841 gggcgctgga gggcaaaggg attatgttgc gttccgagtg ggatgtgttg ccgtttctgg
    45901 agagtggcaa actggtgcga gtattgccgg agtatgcaca aagcgccaat atctgggctg
    45961 tttaccggga gccgctctat cgcagcatga aattacgtgt ctgcgtggaa tttctggcgg
    46021 catggtgcca gcaacggctg ggcaagcccg acgaaggcta tcaggtcatg taaatccacc
    46081 agaaatcact cgggatcctt ttcgcgcttt cttttgaatt tcgtccagat ttttgtctcc
    46141 tgacgacgcc acagacgctg gatgttgtca tgatgacgca gcaggatcag gcaagagagc
    46201 atcgaaaccg ggaaggtgaa ttgtggctta aaccaccaga cataaaacgg agcaatcagt
    46261 gcactgacaa tcgctcccag cgacgagtaa ccactcaata gcacggtcag taaccaggtt
    46321 cccgccatta ctccagtgag atcccagcca attggtgcga tggcaccaaa agcggtagca
    46381 acgccttttc ctcctttaaa accgaagaaa acgggccaga tgtgtccaag acaggcggcg
    46441 atggcaatta agcctagcca gaaggggctg acacctaatt catacgcgcc ccagacgggc
    46501 aacattcctt tcagaacgtc gaaaatcagt actgctacgg ctgctccctt gccaccgata
    46561 cgtaacacat tggttgcgcc aggattgccg gagccgctgg ttcgcggatc gggcagccca
    46621 cacaagcggc aaaccagaat ggcactggaa atggagccgc agaggtacgc gatgaggatc
    46681 attccaggcg cgattgcact cataagctgt tccgttttga aaattcgtgt tcaacgatga
    46741 atctgtggat aatacgcaca tttcgccgga agtggtatcc ggttagccaa aaagcaggca
    46801 ggacgtgatg gatattgtat ttatagagca actttcggta atcaccacta ttggtgttta
    46861 cgactgggaa cagaccatcg aacagaagtt agtgttcgat atcgaaatgg cgtgggataa
    46921 ccgtaaagcg gcgaaaagtg atgatgtggc ggattgcctc agttacgctg acattgcaga
    46981 aacggtggtc agccacgtcg agggggcgcg ttttgcgctg gtggaacgcg tggctgaaga
    47041 ggtggcggag ctgctgttag cacgcttcaa ctcgccgtgg gtgcgtatca aactcagcaa
    47101 gccaggcgca gtggcgcggg cggcgaatgt tggcgtcatc attgagcgtg gcaataatct
    47161 gaaagaaaat aattaatttt acagctgtta aaccaaacgg ttataacctg gtcatactgc
    47221 agtagttcgg acaagcgtta catttttata atttaggggt ttattgatga gcgatatgca
    47281 ctcgctgctg atagcggcaa tattgggtgt ggtcgaagga ttgacagaat ttctgccggt
    47341 atccagcacg ggccatatga ttattgtcgg tcacttgttg gggtttgagg gcgacacggc
    47401 gaaaaccttt gaagtcgtga tccagttagg atcaattctg gctgtggttg tcatgttctg
    47461 gcgacgtctg tttggcctta ttggtattca ctttggtcgc ccgttgcagc acgaaggaga
    47521 aagcaaaggc cgtttaacgc tgatccacat tttgctgggg atgattccgg cggtggtact
    47581 ggggctgttg ttccacgaca cgattaaatc attgtttaac ccgataaatg tgatgtatgc
    47641 actggtcgtt ggcggtctgt tgctgattgc cgctgaatgc ctgaagccga aagagccgcg
    47701 tgcgccgggt cttgatgata tgacctatcg tcaggcgttt atgattggct gtttccagtg
    47761 tctggcgctg tggccgggtt tctcccgttc cggggcgacc atttcaggtg ggatgctgat
    47821 gggtgtgagc cgttatgcgg cttccgagtt ctcgttcctg ctggctgtgc cgatgatgat
    47881 gggcgcaacg gcgctcgatc tctacaaaag ctggggcttc ctgacaaccg gcgatatccc
    47941 gatgtttgcc gttgggttta tcaccgcttt tgtggtggcg ctgatagcga ttaaaacctt
    48001 cctgcaattg attaagcgca tttcgtttat tccgttcgcc atttatcgct ttattgtggc
    48061 ggctgcggtg tatgtcgtgt tcttttgatt gaggaatagt gtcggatatg acgcttgtgc
    48121 gtcttatccg acctaaggga tttctgcaat atactgaatt taaaaagtta atcaggcttt
    48181 gggcaacgtt gttccttcca gctggctacc gccgcaatcc gccgtcgggt cagctcctca
    48241 cgaatctcca cacctttaaa tcctgcttca acgacggctt ttgtcggcac tgactgcgcc
    48301 acttcccagg cttcgcgcaa ccagcggcct tgcgggtagt ccgctgattc aaaaccggtt
    48361 ctgccgcgca cgtcagcctc gctggtcagc gccagttgct cgacacgctg cggtttacgc
    48421 caggcgtcga tggaatcaaa caatttgacg atggtttttg ggttcagcat tgggaaggtg
    48481 tggatgagat cgtgaaactc agccaccagt ctggctaaat cgcgaatttc atttggcacg
    48541 cgcagacgct ggcatagttg ttccactaac ttaacacccg ccgggccatg gccatgatga
    48601 cgcggccaaa gttctggtgg cgtcagtcct ttaccgagat cgtggcataa agttgcgaaa
    48661 cggacatcga cctgcggact cagcatcgcc gccattgaga gcgtcattaa ggtatgaata
    48721 ccggtgtcga tttccggatg ccacctggca ggggccggaa cgccaaacag ggcgtcaatt
    48781 tccgggaata aaacgcgcag tgcgccgcaa tcgcgcagta cctggaagaa cacctgggga
    48841 ttgcgggtgg tgagggcgtt ttccgtctct ttccataccc gttcaggcgt caggtgttcc
    48901 agttcacccg catgggtcat ctcgcgcatc agcgccagag tttcatcggc aatacgaaaa
    48961 ccgaggtggg cataacgcgc agcaaaacgc gccacgcgca gtacgcgtaa cggatcttcg
    49021 ccaaaagcgg gggaaacatg gcgcagcaga cgattttgca gatcgcccag accgttgtac
    49081 gggtcgataa tctcgccgtt atcgtcctgg gccagcgcat taatggtcag atcgcgacgc
    49141 ttaagatcat cttccagcgt gacatccggt gcggcatagc aggtaaaacc ggtgtaaccg
    49201 gaaccggatt tccgttcagt acgtgccagc gcatactctt catgcgtttg cggatgcaga
    49261 aaaacaggaa aatcgcggcc tacctgctgg tagcccgcgt cgagcatctc ctgtggcgta
    49321 ctgccgacca ccacccaatc tctgtctttg accggtagcc ctaacaatgc atcccgaaca
    49381 gcaccaccga ccagataaat cttcacgcca tcatcccttc gtcaaataca caattcctaa
    49441 taataagaca gtgcaacgaa gaaggcgatt tagttcatcc agcgatcttt gcgtttgcgg
    49501 cttgggatca ggtgcggcag taccagaccg agcagcaagc caagccccag cacgccgccg
    49561 ccatacataa accattgcat gatgatggtg cgctgtttgt catccagctg tacgctggcg
    49621 gcatcgacct ttttctgcgc gacaatcagc tcgtttttca gtttctgatt ttcttctttt
    49681 aacccgttga tcacgctgtc gctctgcgcc actttttgct gcatttctgc ggtgcgctga
    49741 ttccaggtgt tatcgatatt ggtgagttta tcggtcaggg ttttgacctg attttccaga
    49801 tctggcacac gggagcgcag gcttggctca gtgctaagtt gtttcaacgg gatccaggcg
    49861 gtacggccag agctgtcttt cacctgggca taattggtgt tggcgtcagt ttgtaataag
    49921 gtcacttcct cgccggcgtt aaccgtgcct acgaggcgat aatgatctcc cggaccgcta
    49981 cggacccagg tattcagttc gtcagaaaca tagcgcgttt cttcagcgtg tgagacggca
    50041 gtcgcgctaa gtgcgagtaa agttaatccg atcaggcgta attttggcat caggctgtcg
    50101 ttattgtcat ggaaagtgga acgatagtag tggcatcagt gtcgctacgc aaagcattcg
    50161 acatcaatcg gaatcctctg tgtcaggtct tgccactgct tcaaactttt acgcccgtca
    50221 aattgcccgt tgcatggcaa tttggcgcaa aatactatct actgacaaaa aagatcgcat
    50281 taagttcgcc gttcatcgtc acttatgtga cataaccgat aagtaaaggc tatggctcag
    50341 gaaatcgaat taaagtttat tgttaatcac agtgccgttg aggcgttgcg tgaccatctc
    50401 aatacgctgg gcggcgagca ccatgacccc gtgcagttgc tgaatattta ctacgaaacg
    50461 ccggataact ggctgcgtgg gcacgacatg ggcttgcgta ttcgtggcga aaacggtcgc
    50521 tatgagatga ccatgaaagt tgcaggaaga gtgacaggcg gcttacacca gcgcccggaa
    50581 tataacgtgg cgttgagcga accgacgctc gacctggcgc agttaccgac ggaagtctgg
    50641 ccgaacggcg aattgcctac cgatctcgct tcccgcgtgc agccgctgtt tagcaccgat
    50701 ttttatcgcg aaaagtggct ggtagaggtt gatggtagcc aaattgaaat cgccctcgac
    50761 caaggggaag tgaaagcggg tgaatttgct gaacctatct gcgagctgga actggaactg
    50821 cttagcggcg acacgcgcgc ggtgctgaaa ctggcgaacc aactggtatc gcaaaccgga
    50881 ttacgccagg gcagcctgag caaagcggcg cgtggctatc atctggcgca gggcaatccg
    50941 gcgcgtgaaa tcaaaccgac caccatttta catgttgcgg caaaagcgga tgtcgagcag
    51001 gggctggaag cggcgctcga gctggcgtta gcgcaatggc agtatcatga agagctgtgg
    51061 gtacgcggca acgatgcggc gaaagagcag gtgctggcag ccattggcct ggtccgtcat
    51121 acgctgatgc tgttcggtgg cattgtgccg cgtaaagcga gcactcactt acgtgatttg
    51181 ctgacccaat gcgaagcgac catcgcttca gcggtttctg ccgtgacggc ggtctattct
    51241 accgaaacgg caatggcgaa gctggcgttg accgaatggc tggtaagcaa agcctggcag
    51301 ccgtttttag atgccaaagc gcagagtaaa atgagcgatt ccttcaaacg ctttgccgat
    51361 atccatcttt cccgccatgc cgctgaactg aaaagcgttt tctgccagcc gttaggcgat
    51421 cgctaccgtg accagttgcc acgtctgacg cgtgatattg actcaatact gttgctggcg
    51481 ggttactatg atcctgtcgt ggctcaagcc tggctggaga actggcaggg gctgcgtcac
    51541 gctattgtga ccgggcaacg cattgaaatt gaacatttcc gtaatgaggc aaacaatcag
    51601 gaaccgttct ggttgcacag cggaaaacgt taatcaggca aggataaaat cgcttatgaa
    51661 gccgctctct tcaccgttac agcagtactg gcagaccgtt gttgagcggc tgccagagcc
    51721 tttagccgac gaatcactta gcgcacaggc gaagtcggta cttactttca gtgattttgt
    51781 gcaggacagc gtgattgcgc atccagagtg gctgacggaa ctggaaagcc aaccgccgca
    51841 ggccgacgaa tggcagcatt actctgcatg gtggcaggag gcgctcagta atgtgagtga
    51901 cgaagccggg ttaatgcgcg agctgcggct attccggcgg cgcattatgg tgcgcatcgc
    51961 ctgggcgcaa acgttggcac tggttactga agagagcata ttgctgcagc tcagccatct
    52021 ggcggagacg ctgattgttg cggcgcgtga ctggctgtat gacgcctgct gccgcgagtg
    52081 gggaacgccg tgcaatgcgc agggcgaagc gcaaccgctg ctgattttag gcatgggtaa
    52141 gctgggcgga ggggaactga atttctcctc agatatcgat ctgatttttg cctggccgga
    52201 acatggttgt acgcagggcg gacgccggga actggataac gcccagtttt ttacccgcat
    52261 ggggcagcgg ctgattaaag tgctggatca accaacgcag gatggcttcg tctatcgcgt
    52321 ggatatgcga ctgcgtccgt ttggcgaaag tggcccgctg gtgctgagct ttgcggcact
    52381 ggaagattat taccaggagc aggggcgcga ctgggagcgt tacgcgatgg tcaaggcgcg
    52441 gattatgggc gatagcgaag gcgtctatgc taacgagttg cgtgcgatgc tgcgcccgtt
    52501 tgttttccgt cgttacatcg atttcagcgt gattcagtcg ctgcgcaaca tgaaagggat
    52561 gattgcccgt gaagtgcgtc ggcgcggttt gaccgacaac atcaaacttg gcgcgggtgg
    52621 cattcgtgaa attgaattta tcgtccaggt attccagctc attcgcggcg ggcgcgaacc
    52681 gtcgctgcaa tcgcgctctt tactgccaac gctcagcgcc attgccgagc tgcatctgct
    52741 ttctgaaaac gatgctgaac aattgcgagt ggcgtatctg ttcctgcggc gtctggaaaa
    52801 cctgctgcaa agcattaacg acgaacaaaa ccagacgctt ccttctgatg agcttaaccg
    52861 tgcgcggctg gcgtgggcga tggactttgc tgactggcag caactgactg gggcgctgat
    52921 cggacatatg accaatgtgc gccgggtgtt taatgaattg attggcgacg acgaaagtga
    52981 aactcaggaa gagtcgctgt cggaacagtg gcgtgagctg tggcaggacg cgttgcagga
    53041 agatgacact acaccagtgc tggcgcatct tagcgaggac gatcgcaaac aggtgctgac
    53101 gctgattgcc gatttccgca aagagctgga taagcgcaca atcgggccac gcggacgtca
    53161 ggtgctcgac catctgatgc cacatctgct aagagatgtc tgtacacgtg aagacgctgc
    53221 tgtaacgctg tcgcgcatta cggccttgct ggtggggatt gttacccgca ccacctattt
    53281 agaattgctc agtgaatttc ctgcggcgct taagcatttg atttctctgt gtgccgcatc
    53341 gccgatgatt gccagccagc tggcgcgcta tccgttattg ctggatgaac tgctcgatcc
    53401 aaacactctc taccagccga cggcgaccga tgcctaccgt gatgaactgc gccagtattt
    53461 gctgcgcgtg ccggaagatg acgaagaaca acagcttgag gcgctgcgtc agttcaaaca
    53521 ggcgcaactg ttacgcattg cggcagcgga tatcgccggt acgctaccgg taatgaaagt
    53581 gagcgatcac ttaacctggc tggcggaagc tatgatagat gccgtcgttc agcaggcgtg
    53641 ggttcaaatg gttgcccgct acggtaaacc gaatcacctg aacgagcgcg aagggcgtgg
    53701 ttttgcggtg gtcggctacg gcaagctggg cggctgggag ttaggctaca gttccgatct
    53761 tgacctgatc ttcctccatg attgcccaat ggatgcgatg actgacggcg agcgggaaat
    53821 cgacgggcga cagttttatc tgcgtctggc gcaacgcatt atgcatctgt tcagtacgcg
    53881 aacctcttcc ggcattttgt atgaagtgga tgctcgactg cgtccatccg gggcggcggg
    53941 aatgctggtg acatccgcag aagcatttgc tgattatcag aaaaacgagg cctggacgtg
    54001 ggaacatcag gcgctggtgc gtgcgcgtgt agtgtacggc gatccgcagc tcaccgcgca
    54061 ctttgacgcg gtgcgtcgcg agattatgac gctgccgcga gaaggtaaaa ctctgcaaac
    54121 ggaagtgcgg gaaatgcgcg agaaaatgcg cgctcatctc ggtaataaac atcgcgatcg
    54181 ctttgatatc aaagccgatg aaggcggaat taccgatatc gaatttatta cccaatatct
    54241 ggtgttgcgc tacgctcatg aaaaaccgaa gttaacgcgc tggtcagaca acgtgcgtat
    54301 tctggagctg ctggcgcaaa acgacattat ggaagagcag gaagcgatgg tgctgacccg
    54361 tgcttacact acgctgcgcg atgaacttca tcatctggca ttacaggaat tgccgggcca
    54421 tgtgtcggag gattgcttca ccgcagagcg tgatctggtg cgggcaagct ggcagaagtg
    54481 gctggtggaa gaatgaagta tggtattatc gcgcgcaaat tttgaatctc tcaggagaca
    54541 ggaatgaaag taacgctgcc agagtttgaa cgtgcaggag tgatggtggt tggtgatgtg
    54601 atgctggatc gttactggta cggtcccacc agccgtatct cgccggaagc gccggtgccc
    54661 gtggttaaag taaataccat cgaagaacgt ccgggcggcg cggctaacgt ggcgatgaat
    54721 atcgcttctc tcggtgctaa tgcacgcctg gtcgggttaa cgggcattga cgatgcggcg
    54781 cgcgcgctga gtaaatctct ggccgacgtc aacgtcaaat gcgacttcgt ttctgtaccg
    54841 acgcatccga ccatcaccaa attacgggtg ctttcccgca accaacagct gattcgtctg
    54901 gattttgaag aaggtttcga aggtgttgat ccgcagccgc tgcacgaacg gattaatcag
    54961 gcgctgagtt cgattggcgc gctggtgctt tctgactacg ccaaaggtgc gctggcaagc
    55021 gtacagcaga tgatccaact ggcgcgtaaa gcgggtgttc cggtgctgat tgatccaaaa
    55081 ggtaccgatt ttgagcgcta ccgcggcgct acgctgttaa cgccgaatct ctcggaattt
    55141 gaagctgttg tcggtaaatg taaaaccgaa gaagagattg ttgagcgcgg catgaaactg
    55201 attgccgatt acgaactctc ggctctgtta gtgacccgtt ccgaacaggg tatgtcgctg
    55261 ctgcaaccgg gtaaagcgcc gctgcatatg ccaacccagg cgcaggaagt gtatgacgtt
    55321 accggtgcgg gcgacacggt gattggtgtc ctggcggcaa cgctggcagc gggtaattcg
    55381 ctggaagaag cctgcttctt tgccaatgcg gcggctggtg tggtggtcgg caaactgggg
    55441 acatccccgg tttcgccgat cgagctggaa aacgcagtac gtggacgtgc agataccggc
    55501 tttggtgtga tgaccgaaga ggaactgaag tttgctgtag cggcagcgcg taaacgcggt
    55561 gaaaaagtgg tgatgaccaa tggcgtcttt gacatcctgc acgccggaca cgtctcttat
    55621 ctggcaaatg cccgcaagct gggtgaccgt ttgattgtcg ccgtcaacag cgatgcctcc
    55681 accaaacggc tgaaagggga ttcccgcccc gttaacccgc tcgaacagcg tatgattgtg
    55741 ctgggcgcac tggaagcggt cgactgggtg gtgtcgtttg aagaagacac gccgcagcgc
    55801 ttgattgccg ggatcctgcc agatctgctg gtgaaaggcg gcgactataa accagaagag
    55861 attgccggga gtaaagaagt ctgggccaat ggtggcgaag tgctggtgct caactttgaa
    55921 gacggttgct cgaccactaa cattatcaag aagatccaac aggataaaaa aggctaaccg
    55981 gaaagcgctt cacagatctc gcttcgaacc tggcaggcct attgacgctg ttgttttttc
    56041 aacctaaagt aaaggaacaa gggtgaggga ggatttctcc cccctctgat tggctgttaa
    56101 taagtggcga aacttacaag taacaacaca atcagtatga tgacgagctt catcataacc
    56161 ctttccttct gtaaggcccc ttcctcggga ggggctttcc cgtttcagcc ccttgctgac
    56221 tccccgattg ttgatgagcg ccggactccg cgcaacgctt tcccagaggc agttttgcct
    56281 tccccgagca gtcacgcaaa atgctgcaac agcctgatca tttgcacctt ttagcggaac
    56341 gcagatataa aaaatccccg gctttttggg ccagggatta ttcatagaag agggtttact
    56401 ctgctttttc ttcgacggga gttgttgagc ttaaggatga agtcaatgcc gccagtgagc
    56461 cgcctgaaac gccaatttca ttgagcaagg agtcaatcag cggtgcctgt gtgcggtaag
    56521 agagtgcggc tgataacgct tgttctgcca ggtttccgcc ccccacatta cccgtgtttg
    56581 catcacccgt agcgccacca cgattcagcc catcgacctg aataattttg atgccgtcga
    56641 tagacttcat tggttccacg gatttctcaa ttaccgcagg cagcgcctgc aataatgcca
    56701 gtttgaattt aaggctggtt tgctcgtcag aaagtacgtt gatagcgtcg ttcagcgcac
    56761 gttgtgcttc tgcttccgcc aggccttttt tgcgtgttgc ttcggctaac tcaacgatcg
    56821 ccgccgcctg catctctgcg gcttctttct ctgctttcgc ccgcacggtc agttcaaccg
    56881 ctttggtttc tgcatcctgc gcggcagcga ttagggcaac ttgtttagca cgatcggctt
    56941 ctgcggtctg gcgagtggtt tctacgtttt gctgggcgct taccgcttct gcaagtgcaa
    57001 ggttggcacg cgcttccgct tgtgactgct gttccgattt ggcggcaata gcgatcgatt
    57061 tcgtctggtt ggcgatttcg gtgacctgct gctgttcgat ctctttaatg cgaacttcac
    57121 gttcagcttc aacttttctg gaacggacgg cctgttcgcg gtcgatttcc gtttcctgaa
    57181 tctgtcgttc agccagaatt cgcgtctgct ctgcttcacg acgacgttca gcttcaaaag
    57241 ccgcaatttt cgcattctgc tcagcggtac gggttttaac ctgctgctcc tgctcaagcg
    57301 tcataaacgc ttcttgttgt tcaatctcca acttgcgcga aagtgcatca cggtttttct
    57361 cacgcaccgc aacttctaca tcctgttcaa cttcgttacg ttcgcgacga cggcgctccg
    57421 tctcctgcgt cagcttggtt aaaccttcgg cgtcaaaggc gttgttagga ttgaaatgtt
    57481 ctttcgacgt ctggttaaag ttggtaagtg aaacgctttc cagttccagg ccgtttttcg
    57541 acagatcttc agcaacggta ttttgtacgc cctgcacgaa gttctcgcgg gtatcctgta
    57601 actcatgcat ggtcatttgt gcagctgttg cacggagggc atcgacaaat ttatcttcaa
    57661 ccaacatacg taagtcttca ggcgacaggg tgcgttgccc cagcgtctgg gcggcggtgg
    57721 caataccttc cactgacggt tttacccgca caaagaaagc gacaacgaca tcgacgcgca
    57781 tacgatcttt cgtaatcagg ctatcaatgg ttgagcggct gacttccagc ttcagagtat
    57841 tcatattgat ggggattatt tcatgaaaga tcggcatcac gattgcgcca ccgctcatta
    57901 ccactttttg cccacctaaa ccagtacgaa caaaagcttg ctctgccgaa gcgcgacgat
    57961 agagcctggc gaaaataatt ccaataataa acagaatgca tacggcaata atcgcggtaa
    58021 acatccagga gggcacagaa ttaacaatat catccattat taaatttcct tttgattaat
    58081 aaattacaat atttggggcc agggattgtt ttccgccaaa tatcgagttg cagaaagtcg
    58141 gcaaataatt aacactttgt ctcctttagt gaaaattttt ccttcttcag gctccagtag
    58201 taaataatgt atttggccaa attgatcggt gagttttcct tcgcagggat tacctgaagt
    58261 ggcttgatga ccggtaatta acgccatgct accaatatat tcttcttctg taatagctga
    58321 gctatgatcg cgtggaatcc agggcgcaac tattttaccg gtataatgca ccgcaataat
    58381 cgtaaacagt aaactgacag gaaccacaaa caggttcgag agtggtgatt gccagaccat
    58441 gatgcaggta tgctgcaaca ggatgccaat aagaccaaaa aaaccagcca gtaagcaaag
    58501 aacgacgaga gctggcaatc ttccgatatt gagataatga agtgcctggc taatatgacc
    58561 tgtggttatg gaatcataat ggtcaagatg tgcatcaagt gcaccggaga gcatgtgacc
    58621 gcagataagc gcaaaaattt ctaaaaggcc gatcaacagt acaaaggaaa tagcgaaaag
    58681 ataaggggtg ttatagtcgg cgaataaaat catatgtcac tccaatgtcc atttagtgac
    58741 gcaatattta ctttaggata gtttccttgc ttacatttat ctttgttaat aataacacat
    58801 gttagagaag ttctggaaga gaaagtcttt taatatggtt ttttattttt cactaaaaag
    58861 tgtgatcggg gacaatatat ttacgcacgt tatgtttaaa ggcactacac tgattgggga
    58921 atactgaaat cagaaaaagc atatggcctt aaaaggtatg cgataaccgg aggatgtgct
    58981 tatggatcat agtcttaatt ctttaaataa tttcgatttc ctggcgcgta gttttgccag
    59041 aatgcacgca gaaggtcgcc cggtcgatat tctggccgtt actggtaaca tggatgaaga
    59101 acatagaacc tggttttgcg cacgttatgc ctggtattgc caacaaatga tgcaaaccag
    59161 agaacttgaa ttagaacact gatattacgg gccgtctggc ccgtttttgt gttgctttat
    59221 tctgctttat caataggcgg gatagccgga ggagattgaa gatctgctac cgaattattg
    59281 cgcgcttcca gttcactgat gcgctgctcc agtaacgcca gtttttcacg agtccgtaac
    59341 aggacttgcg tctgaacgtc gaattcttcg cggcttacca gatcgagacg cgtcagctgc
    59401 gcttgtaggg tttggcggat ttttttctcc acatcttccc cgaactccct gattccttta
    59461 ggcattgatt cgtgaacctg gcgagcgatt tgctcaattt ttttcgggtc aatcattgta
    59521 gtttccctgt actgataggt gttgagtgcc attgtagtgc gataagggta agtcataaac
    59581 cagaattatg tgaagctatg cgttgctgcc gctaatcatt agcgttatag tgaatccgct
    59641 tattctcagg gcggggcgaa attccccacc ggcggtaaat caactcagtt gaaagcccgc
    59701 gagcgctttg ggtgcgaact caaaggacag cagatccggt gtaattccgg ggccgacggt
    59761 tagagtccgg atgggagaga gtaacgattc tgtcgggcat ggacccgctc acgttatttt
    59821 ggctatatgc cgccactcct aagactgccc tgattctggt aaccataatt ttagtgaggt
    59881 ttttttacca tgaatcagac gctactttcc tcttttggta cgcctttcga acgtgttgaa
    59941 aatgcactgg ctgcgctgcg tgaaggacgc ggtgtaatgg tgcttgatga tgaagaccgt
    60001 gaaaacgaag gcgatatgat cttcccggca gaaaccatga ccgttgagca gatggcgctg
    60061 accattcgcc acggtagcgg tattgtttgc ctgtgcatta ctgaagatcg ccgtaaacaa
    60121 ctcgatctgc caatgatggt agaaaataac accagcgcct atggcaccgg ttttaccgtg
    60181 accattgaag cggctgaagg tgtgactacc ggtgtttctg ccgctgaccg tattacgacc
    60241 gttcgcgcag cgattgccga tgacgcaaaa ccttctgatc tgaatcgccc gggccacgtt
    60301 ttcccacttc gcgcgcaggc aggtggagta ctgacgcgtg gcggccatac tgaagcaact
    60361 attgatctaa tgacgctggc aggctttaaa ccggctggtg tgctgtgtga gctgactaat
    60421 gacgatggca cgatggcgcg tgcaccagag tgcattgagt ttgccaataa acacaatatg
    60481 gcgctcgtga ctattgaaga cctggtggca taccgtcagg cacatgagcg taaagccagc
    60541 tgaaaaccgc tgcttaattt actgccttaa tcaagaaacc gaagttgtag caggcttcgg
    60601 tttttatttt tccctgctat gcaagatgtt aattccgctt ctctttctat gagaaaattt
    60661 cattaatatc aggcattctt tttcattatg atcaaaatca tataattgtt ccgttattat
    60721 gcgaccatat gaatatatcc gaaaaaggat atgtgaaatt tatgcgctaa atgtttagta
    60781 ttgttaaata ttaagggtaa aaggatgttt atcgcctggt actggattgt attgattgct
    60841 cttgttgttg tgggttattt cctgcatttg aaacgttatt gtcgggcgtt tcgccaggac
    60901 agagacgcac tgcttgaagc gcggaacaaa tacttaaaca gtacgagaga agagacagcc
    60961 gaaaaggtag aataaggctt tagtgaagct ggcagaagtt gtccatgcgc tggacaactt
    61021 ctgatgttgc ttttaaccaa ttcccgccgt ttgtagcagc actaaactga atcccatcac
    61081 tgacattcca catagtacgc catagctggg gttattatta gggtcaatct ctttggcgag
    61141 cggcattaat tcatcaaccg agagcgctac cataattcct gcaaccgccg ccatgattgc
    61201 cgccatgacc accggggaaa tcatgctacc gaggattaac cacgccagca caccaccaag
    61261 aatttctgcc agtccagaaa tccccgccca aagaatcgcg gtgcgtttag accccgttgc
    61321 cgcgtaaacc gggcctgcaa ccgccagacc ttcaggaata ttgtgtaacg caacggccag
    61381 tgcgatgcca aagcccagct ctaggttgct gctcgccgtg acaaaggtgg caatcccttc
    61441 cgggaagtta tgcagactga tgccgagagt gagcagaatg gctgtgcgct tgatcgattt
    61501 tggcaacggc tgcaccgatt tttgcattaa atcctgcgga tgcgcatgtg gcaacatgcg
    61561 gtccaggcca aaatagccaa gcagaccgaa gataaacatt ccataaccca acacaggtga
    61621 cattccttcg gcggctaatg cggcaggaag catttccatt aatgagatga gcaacatgat
    61681 ccccgccgca aatcctagcg aaaacgccag taagcggttc gagggttttt gcccgagaac
    61741 gccgagaaac gcgccaataa acgtggctgc ccccgccagt atggtcagaa tgagaggtac
    61801 tgacatcgac aactccttat aaatcttcac cttcaggcag atcgtcaaaa taactgatga
    61861 tcatcatcat tgttatccgg gttcttactc cgccgaacaa gcgtattgtg aggatatcaa
    61921 aatgacacct ttagttaagg atatcatcat gtcttcaaca cgtatgccag cattgttttt
    61981 aggtcacggt agtccgatga acgtgctgga agataatttg tatacccgca gctggcagac
    62041 gttggggatg acattgccac gcccgcaagc aatagtggtg gtttcggctc actggtttac
    62101 ccgtggaaca ggagtgaccg cgatggagac gccgcccacg attcatgact ttggtggctt
    62161 cccgcaggcg ctgtacgata cgcattatcc tgctccgggt tcacctgcgc tggcacagca
    62221 tctggttgag ctgttagcgc cggtccctgt gacgctggat aaagaagcct ggggcttcga
    62281 ccacggctcg tggggcgtac tgattaagat gtatcctgac gccgatatcc cgatggtgca
    62341 gttgagtatc gacagtagca aacctgccgc ctggcatttc gaaatggggc gcaaactcgc
    62401 ggcgctgcgt gatgaaggga taatgttggt cgccagtggc aacgtggtgc ataacctgcg
    62461 tacagtgaag tggcacggtg atagttcacc gtatccgtgg gcgacgtcgt ttaatgagta
    62521 tgtgaaagcg aatctgacgt ggcaagggcc ggtggaacaa catcctctgg tgaattatct
    62581 cgaccatgaa ggtggcgcgt tatcgaaccc aacgccagag cactatctgc cgttgttgta
    62641 tgtcttaggt gcgtgggatg ggcaggagcc aattaccatt ccggtcgatg gtatagaaat
    62701 gggcagttta agtatgctgt cggtgcagat aggttaataa aagaacccga agccagaatg
    62761 actggcttcg ggtgttgctg agttagcctc tgatgatttt aagcgcccat gcgccactca
    62821 taatgaccag cagcaccaga cacataccaa aagccagcat acaagcctga gccatattca
    62881 taaaatgcca tggtggtagc agataccagc cttcagattg ctgatacatt tccacaaacc
    62941 actgttgcgt gctgctcagt gtgacgtcat caggaacgat tggtgcgtca tagccacaat
    63001 ccccggtagg cttgaaccaa tttggtgccc actgtgccag cggcaggtta aagggaaaag
    63061 ttggatcggt agagcaaccc tgtacgccaa acagtgaatc gggatccgga ttatgtactg
    63121 catggtggat atcgttcagt ttgagcgaaa acttcagtcc caaaatgctg ccgtaaaatg
    63181 ccatcacgca gccaattagc tttaggatga tgttctttgg gttgatcgct gcaaccaatc
    63241 ctccaataac catcacaaac atggcgtagc gaatgtatac acattgctca cagggtgcca
    63301 tgtagagata gatctggaag aaagagtgcg ccaggataat taacgcgccc atcgcaacgg
    63361 ccattaacaa ccacaacaag cgttgctcct gccatctgac cagtgtgtca actggtgatg
    63421 tgcgaagatc tttccacatt cccttaatac ccatagcctg tttccctgtt atttgcttgc
    63481 taactcacgg ataaggtctg ccatcgcgtc gatggatttg atgctcttgg tgtagatcaa
    63541 gtacttacca ttaacgacat aggctggaac cccctggatt ttggcgacat cataagaggc
    63601 tttccatttt tccagtgttt cttgaaccgc tggttctttc agtgccgctt caaaatccgc
    63661 ctgactcata cctgcggcat ccagaccggt tttgataaaa gcagccggat ctttaccgtc
    63721 agaccagcgt tcttttttgt cgtgataagc cgcgtagtag gcaaacttgg ctttcttaaa
    63781 ctgagagtta gcatcaaata aggaaatgcc tgctgcttta tctttattga tcaagaccgc
    63841 aaagacttcg cttgcttgtt tgccgtattc acctttggtt tccagatgga acggcgtgaa
    63901 agcaacgata tctttcactt tttccgatac cggaccggta accgctttgt cgtacttgta
    63961 acagaacggg caggcgtagc tgaatacctt aatcagcgtt ttgtctgcat tcggaatagg
    64021 tttttccaga accatgtaat ccgtgccttc ggtaaatgca gaagcggtaa atgaaacagc
    64081 caaagctgcg gtaagcagta tgcttttaaa tagtgatgag atccctaatt tcgacatttt
    64141 tattcccttc ttaattattt gaacatctgt tgtggacgga ctaacaatgc acgatagtga
    64201 gtctgattgg gtttatctga cagcacgtcg atttccactt tcacttcttt ggttttgtaa
    64261 tcgatttcgt tcaacttacc gacggttggc tgcccgacat cgaacaaatg aatagaacca
    64321 ccgaagccaa acatggtgtt acggtcggct tgatattcaa tgatggaggt gattgggcta
    64381 tagaaatcgt agccacgttc tttaccgtat tcccacactt gctgaacggt gcctttcttc
    64441 tcatcaatct tatattccac aaagcgggag tatttcatgg ttggtaaggc aggttgttcc
    64501 agatgacgcc catcgccatt atcaaaaatg gtgagcgttc ctttgctgga aatccaggcg
    64561 gtatgctggg tgtaggtaaa gtcgaagtct gagttttcgc acaggccatt ttcgttacag
    64621 gtaattggct taccgttagc atcaaccggt ttcagcagct tgctggccag cggtttttcc
    64681 caacctttag agggcgcaag gatccatttc actagcttat cacgaccaat tttcacaaca
    64741 ccctggtggc gagaggagag gatgattgag tcatcttttg cgtcataggc gatagagttc
    64801 acgtgcgccc agttgcggcc tggccctaca cccagcgcgt cgccgaacgg tgtatctggt
    64861 tccagttttg cctgttgtcc tgcatgggca aggtcaacgt taacgcaaac tgcacctgca
    64921 tccagcgcgc cgagcagtgc atcgcgtttc ggatcgagga tcttggtcag atcccataca
    64981 tcgacaacgc gaccagattt atcgacttcg aggatatggt cacgaatggt ggtgacgtgt
    65041 acgccgtcat cgcgacgata gttactctta cctacgcgca acagtaccgt gccatttggc
    65101 gtctcaatgg actcatgagt ggcgtcagca aatccgcgcg gtagtttgtg atcttcgagc
    65161 acctgcccca tcatgtcgaa ctcgtaccag tgctgacctt gtacagcggt aaaggtgccg
    65221 cgtggcgttt cacggatacc catcagataa ctacgtttgt taatgttgcg gtcacgacca
    65281 tcgtagaagg tgttttgatc caaccaccag cggtattcgc cttccgtatc gacgataaag
    65341 gtgaatggcg cgatatcaaa agggagtgcg ccagttgccg gacccgcatc aaggataccg
    65401 gcatttttat ctttctcacc atgccagtgg agatcggaac cttgggcggt aaaggtgtgg
    65461 gtattaacca gatagaggcg atcttcaaaa cctggcgcga ctttaacgac tttggtttgc
    65521 tgtaggtcgg agatggagcg gttatccatg taattgttga cgatggccga agtgtgcacc
    65581 acataatcat ctttcatgac cttgccgttt tctttccact caacggtcac tttgttagca
    65641 aatttctgat aaagaccaaa aatcggtaca ccatcgtaag tttttagtga ttcctgaccc
    65701 acgggatagc tgatttctac gcctttttcg cccttcccat ggacggtaac tttgacgtca
    65761 gaaataacat ggctatctaa gtcaaccaaa gcggtcagtg gtgcattgcc gtagggatcg
    65821 acaatgaccg cacccagttg cccggcaggc ggcgctggtt taaaacccgc agccatcacc
    65881 cccgatgctg acaaacccag ggttatcgcc acagttccgg ctacgagtgt ttttctatat
    65941 ttatcaaaca tggatatatc tccttatata acgcaaatat ataataatga tgaatatcga
    66001 ctgttgagag ggttctaata aattcgttac gtgaatatga atattaattc aataaagagt
    66061 gagaatgctt ttgtgtttct tttaaatatg ttgttattcg gtgaaacaaa tatttatgtt
    66121 taatggatag taggggggca atatatcaat cacaatgttc aatactgtgt agtgtgatcc
    66181 ctgcaacatt gttttttaat tattaaattt aaatctggtg agataaaagt aaagtattta
    66241 aataatatca aat
//
LOCUS       DADXDL010000014        62107 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.014, whole genome shotgun sequence.
ACCESSION   DADXDL010000014 DADXDL010000000
VERSION     DADXDL010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 62107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 62107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..62107
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.014"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(112..1062)
                     /gene="dusC"
                     /locus_tag="IRB70_001180"
     CDS             complement(112..1062)
                     /gene="dusC"
                     /locus_tag="IRB70_001180"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(16) synthase DusC"
                     /protein_id="HBC0631122.1"
                     /translation="MRVLLAPMEGVLDSLVRELLTEVNDYDLCITEFVRVVDQLLPVK
                     VFHRICPELQNASRTPSGTLVRVQLLGQFPQWLAENAARAVELGSWGVDLNCGCPSKT
                     VNGSGGGATLLKDPELIYQGAKAMREAVPAHLPVSVKVRLGWDSGEKKFEIADAVQQA
                     GATELVVHGRTKEQGYRAEHIDWQAIGEIRQRLNIPVIANGEIWDWQSAQQCMTISGC
                     DAVMIGRGALNIPNLSRVVKYNEPRMPWPEVVALLQKYTRLEKQGDTGLYHVARIKQW
                     LSYLRKEYDEATELFQHVRMLNNSPDIARAIQAIDIDKLR"
     gene            1301..1699
                     /locus_tag="IRB70_001181"
     CDS             1301..1699
                     /locus_tag="IRB70_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBC0631123.1"
                     /translation="MSKTLNIIWQYLRAFVLIYACLYAGIFIASLLPVTIPGSIIGML
                     ILFVLLALQILPAKWVNPGCYVLIRYMALLFVPIGVGVMQYFDLLRAQFGPVVVSCAV
                     STLVVFLVVSWSSQLVHGERKVVGQKGSEE"
     gene            1696..2391
                     /locus_tag="IRB70_001182"
     CDS             1696..2391
                     /locus_tag="IRB70_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidB/LrgB family autolysis modulator"
                     /protein_id="HBC0631124.1"
                     /translation="MMANIWWSLPLTLIVFFAARKLAARYKFPLLNPLLVAMVVIIPF
                     LMLTGISYDSYFKGSEVLNDLLQPAVVALAYPLYEQLHQIRARWKSIITICFIGSVVA
                     MVTGTSVALLMGASPEIAASILPKSVTTPIAMAVGGSIGGIPAISAVCVIFVGILGAV
                     FGHTLLNAMRIRTKAARGLAMGTASHALGTARCAELDYQEGAFSSLALVLCGIITSLI
                     APFLFPIILAVMG"
     gene            2521..3405
                     /gene="cdd"
                     /locus_tag="IRB70_001183"
     CDS             2521..3405
                     /gene="cdd"
                     /locus_tag="IRB70_001183"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBC0631125.1"
                     /translation="MHPRFQTAFAQLADNLQSALEPILADKYFPALLTGEQVSSLKSA
                     TGLDEDALAFALLPLAAACARTPLSNFNVGAIARGVSGTWYFGANMEFIGATMQQTVH
                     AEQSAISHAWLSGEKALAAITVNYTPCGHCRQFMNELNSGLDLRIHLPGREAHALRDY
                     LPDAFGPKDLEIKTLLMDEQDHGYALTGDALSQAAIAAANRSHMPYSKSPSGVALECK
                     DGRIFSGSYAENAAFNPTLPPLQGALILLNLKGYDYPDIQRAVLAEKADAPLIQWDAT
                     SATLKALGCHNIDRVLLA"
     gene            3555..4274
                     /gene="sanA"
                     /locus_tag="IRB70_001184"
     CDS             3555..4274
                     /gene="sanA"
                     /locus_tag="IRB70_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane permeability protein SanA"
                     /protein_id="HBC0631126.1"
                     /translation="MLKRVFLSLLVLIGLLLLTVLGLDRWMSWKTAPYIYDELQDLPY
                     RQVGVVLGTAKYYRTGVINQYYRYRIQGAINAYNSGKVNYLLLSGDNALQSYNEPMTM
                     RKDLIAAGVDPSDIVLDYAGFRTLDSIVRTRKVFDTNDFIIITQRFHCERALFIALHM
                     GIQAQCYAVPSPKDMLSVRIREFAARFGALADLYIFKREPRFLGPLVPIPAMHQVPED
                     AQGYPAVTPEQLLELQKKQGK"
     gene            4277..4516
                     /locus_tag="IRB70_001185"
     CDS             4277..4516
                     /locus_tag="IRB70_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2542 family protein"
                     /protein_id="HBC0631127.1"
                     /translation="MDVQQFFVVAVFFLIPIFCFREAWKGWRAGAIDKRVKNAPEPVY
                     VWRAKNPGLFFAYMVAYIGFGILSIGMIVYLIFYR"
     gene            4710..5948
                     /gene="preT"
                     /locus_tag="IRB70_001186"
     CDS             4710..5948
                     /gene="preT"
                     /locus_tag="IRB70_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreT"
                     /protein_id="HBC0631128.1"
                     /translation="MPQQNYLDELTPAFTPLLAIKEASRCLLCHDAPCSQACPAQTDP
                     GKFIRSIYFRNFKGAAETIRENNALGAVCARVCPTEKLCQSGCTRAGVDTPIDIGRLQ
                     RFVTDFEQQTGMEIYQPGTKTLGKVAIIGAGPAGLQASVTLTNQGYDVTIYEKEAQPG
                     GWLRNGIPQFRLPQSVLDAEIARIEKMGVTIKCNNEIGNTLTLEQLKAENRAVLVTVG
                     LSSGSGLPLFEHSDVEIAVDFLQRARQAQGDISIPQSALIIGGGDVAMDVASTLKVLG
                     CQAVTCVAREELDEFPASEKEFASARELGVSIIDGFTPVAVEGNKVTFKHVRLPGELT
                     MAADKIILAVGQHARLDAFAELEPQRNTINTQNYQTRDPQVFAAGDIVEGDKTVVYAV
                     KTGKEAAEAIHHYLEGACSC"
     gene            5942..7177
                     /gene="preA"
                     /locus_tag="IRB70_001187"
     CDS             5942..7177
                     /gene="preA"
                     /locus_tag="IRB70_001187"
                     /EC_number="1.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416652.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent dihydropyrimidine dehydrogenase
                     subunit PreA"
                     /protein_id="HBC0631129.1"
                     /translation="MLTKDLSITFCGVKFPNPFCLSSSPVGNCYEMCAKAYDTGWGGV
                     VFKTIGFFIANEVSPRFDHLVKEDTGFIGFKNMEQIAEHPLEENLAALRRLKEDYPDK
                     VLIASIMGENEQQWEELARLVQEAGADMIECNFSCPQMTSHAMGSDVGQSPELVEKYC
                     RAVKRGSTLPMLAKMTPNIGDMCEVALAAKRGGADGIAAINTVKSITNIDLNQKIGMP
                     IVNGKSSISGYSGKAVKPIALRFIQQMRTHPELRDFPISGIGGIETWEDAAEFLLLGA
                     ATLQVTTGIMQYGYRIVEDMASGLSHYLADQGFDSLQEMVGLANNNIVPAEDLDRSYI
                     VYPHINLDKCVGCGRCYISCYDGGHQAMEWSEKTRTPHCNTEKCVGCLLCGHVCPVGC
                     IDLGEVKFKKGEKEHPVTL"
     gene            complement(7248..8258)
                     /gene="mglC"
                     /locus_tag="IRB70_001188"
     CDS             complement(7248..8258)
                     /gene="mglC"
                     /locus_tag="IRB70_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     permease MglC"
                     /protein_id="HBC0631130.1"
                     /translation="MSALNKKSFLTYLKEGGIYVVLLVLLAIIIFQDPTFLSLLNLSN
                     ILTQSSVRIIIALGVAGLIVTQGTDLSAGRQVGLAAVVAATLLQSMDNANKVFPEMAT
                     MPIALVILIVCAIGAVIGLINGLIIAYLNVTPFITTLGTMIIVYGINSLYYDFVGASP
                     ISGFDSGFSTFAQGFVALGSFRLSYITFYALIAVAFVWVLWNKTRFGKNIFAIGGNPE
                     AAKVSGVNVGLNLLMIYALSGVFYAFGGMLEAGRIGSATNNLGFMYELDAIAACVVGG
                     VSFSGGVGTVIGVVTGVIIFTVINYGLTYIGVNPYWQYIIKGAIIIFAVALDSLKYAR
                     KK"
     gene            complement(8274..9794)
                     /gene="mglA"
                     /locus_tag="IRB70_001189"
     CDS             complement(8274..9794)
                     /gene="mglA"
                     /locus_tag="IRB70_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020883197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/methyl galactoside ABC transporter
                     ATP-binding protein MglA"
                     /protein_id="HBC0631131.1"
                     /translation="MVSSTTPSSGEYLLEMSGINKSFPGVKALDNVNLKVRPHSIHAL
                     MGENGAGKSTLLKCLFGIYQKDSGTILFQGKEIDFHSAKEALENGISMVHQELNLVLQ
                     RSVMDNMWLGRYPTKGMFVDQDKMYRETKAIFDELDIDIDPRARVGTLSVSQMQMIEI
                     AKAFSYNAKIVIMDEPTSSLTEKEVNHLFTIIRKLKERGCGIVYISHKMEEIFQLCDE
                     VTVLRDGQWIATEPLAGLTMDKIIAMMVGRSLNQRFPDKENKPGEVILEVRNLTSLRQ
                     PSIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANE
                     AINHGFALVTEERRSTGIYAYLDIGFNSLISNIRNYKNKVGLLDNSRMKSDTQWVIDS
                     MRVKTPGHRTQIGSLSGGNQQKVIIGRWLLTQPEILMLDEPTRGIDVGAKFEIYQLIA
                     ELAKKGKGIIIISSEMPELLGITDRILVMSNGLVSGIVDTKTTTQSEILRLASLHL"
     gene            complement(9855..10853)
                     /gene="mglB"
                     /locus_tag="IRB70_001190"
     CDS             complement(9855..10853)
                     /gene="mglB"
                     /locus_tag="IRB70_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/glucose ABC transporter
                     substrate-binding protein MglB"
                     /protein_id="HBC0631132.1"
                     /translation="MNKKVLTLSAVMASMLFGAAAHAADTRIGVTIYKYDDNFMSVVR
                     KAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEK
                     ARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNK
                     DGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAW
                     LSGPNANKIEVVIANNDAMAMGAVEALKAHNKSSIPVFGVDALPEALALVKSGALAGT
                     VLNDANNQAKATFDLAKNLADGKGAADGTNWKIDNKVVRVPYVGVDKDNLAEFSKK"
     gene            complement(11133..12173)
                     /gene="galS"
                     /locus_tag="IRB70_001191"
     CDS             complement(11133..12173)
                     /gene="galS"
                     /locus_tag="IRB70_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708050.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalS"
                     /protein_id="HBC0631133.1"
                     /translation="MITIRDVARQAGVSVATVSRVLNNSTLVSADTREAVMKAVSELD
                     YRPNANAQALATQVSDTIGVVVMDVSDAFFGALVKAVDLVAQQHQKYVLIGNSYHEAE
                     KERHAIEVLIRQRCNALIVHSKALSDDELAQFMDNIPGMVLINRVVPGYAHRCVCLDN
                     LSGARMATRMLLNNGHQRIGYLSSSHGIEDDAMRKAGWMSALKEQNIIPPESWIGTGT
                     PDMPGGEAAMVELLGRNLQLTAVFAYNDNMAAGALTALKDNGIAIPLHLSIIGFDDIP
                     IARYTDPQLTTVRYPIASMAKLATELALQGAAGNIDPRASHCFMPTLVRRHSVATRQN
                     AAAITNSTNQAM"
     gene            complement(12315..13472)
                     /locus_tag="IRB70_001192"
     CDS             complement(12315..13472)
                     /locus_tag="IRB70_001192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF418 family protein"
                     /protein_id="HBC0631134.1"
                     /translation="MERNVTLDFVRGVAILGILLLNISAFGLPKAAYLNPAWYGAITP
                     QDAWTWAFLDLIGQVKFLTLFALLFGAGLQMLLPRGRRWIQSRLTLLVLLGFIHGLLF
                     WDGDILLAYGLVGLICWRLVRDAPSVKSLFNTGVMLYLVGLGVLLLLGLISDSQTSRA
                     WTPDASAILYEKYWKLHGGVEAISNRADGVGNSLLALGAQYGWQLAGMMLIGAALMRS
                     GWLKGQFSLRHYRRTGFVLVAIGVTINLPAIALQWQLDWAYRWCAFLLQMPRELSAPF
                     QAIGYASLFYGFWPQLSRFKLVLAIACVGRMALTNYLLQTLICTTLFYHLSLFMQFDR
                     LELLAFVIPVWLANIFFSVIWLRYFRQGPVEWLWRQLTLRAAGPAISKTSR"
     gene            complement(13489..14157)
                     /gene="folE"
                     /locus_tag="IRB70_001193"
     CDS             complement(13489..14157)
                     /gene="folE"
                     /locus_tag="IRB70_001193"
                     /EC_number="3.5.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP cyclohydrolase I FolE"
                     /protein_id="HBC0631135.1"
                     /translation="MPSLSKEAALVHEALVARGLETPLRPPVHEMDNETRKSLIAGHM
                     TEIMQLLNLDLADDSLMETPHRIAKMYVDEIFSGLDYANFPKITLIENKMKVDEMVTV
                     RDITLTSTCEHHFVTIDGKATVAYIPKDSVIGLSKINRIVQFFAQRPQVQERLTQQIL
                     IALQTLLGTNNVAVSIDAVHYCVKARGIRDATSATTTTSLGGLFKSSQNTRHEFLRAV
                     RHHN"
     gene            14415..15251
                     /gene="yeiG"
                     /locus_tag="IRB70_001194"
     CDS             14415..15251
                     /gene="yeiG"
                     /locus_tag="IRB70_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HBC0631136.1"
                     /translation="MEMLEEHRCFEGWQQRWRHDSSTLNCPMTFSIFLPPPRDHTPPP
                     VLYWLSGLTCNDENFTTKAGAQRVAAELGIVLVMPDTSPRGEQVANDDGYDLGQGAGF
                     YLNATQPPWATHYRMYDYLRDELPALIQSQFNVSDRSAISGHSMGGHGALIMALKNPG
                     KYTSVSAFAPIVNPCSVPWGIKAFSTYLGEDKNAWLEWDSCALMYASNAQNAIPTLID
                     QGDNDQFLADQLQPAVLAEAARQKAWPMTLRIQPGYDHSYYFIASFIEDHLRFHAQHL
                     LK"
     gene            complement(15282..17273)
                     /gene="cirA"
                     /locus_tag="IRB70_001195"
     CDS             complement(15282..17273)
                     /gene="cirA"
                     /locus_tag="IRB70_001195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catecholate siderophore receptor CirA"
                     /protein_id="HBC0631137.1"
                     /translation="MFRLNPFVRVGLCLSAISCAWPVLAVDDDGETMVVTASSVEQNL
                     KDAPASISVITQEDLQRKPVQNLKDVLKEVPGVQLTNEGDNRKGVSIRGLDSSYTLIL
                     VDGKRVNSRNAVFRHNDFDLNWIPVDSIERIEVVRGPMSSLYGSDALGGVVNIITKKI
                     GQKWSGTVTVDTTVQEHRDRGDTYNGQFFTSGPLIDGVLGMKAYGSLAKREKDDPQNS
                     TTTDTGETPRIEGFSSRDGNVEFAWTPNQNHDFTAGYGFDRQDRDSDSLDKNRLERQN
                     YSVSHNGRWDYGTSELKYYGEKVENKNPGYSSPITSESNTVDGKYTLPLTAINQFLTV
                     GGEWRHDKLSDAVNLTGGTSSKTSASQYALFVEDEWRIFEPLALTTGVRMDDHETYGE
                     HWSPRAYLVYNATDTVTVKGGWATAFKAPSLLQLSPDWTSNSCRGACKIVGSPDLKPE
                     TSESWELGLYYMGEEGWLEGVESSVTVFRNDVKDRISISRTSDVNAAPGYQNFVGFET
                     GANGRRIPVFSYYNVNKARIQGVETELKIPFNDEWKLSLNYTYNDGRDVSNGENKPLS
                     DLPFHTANGTLDWKPLALEDWSFYVSGHYTGQKRADSATAKTPGGYTIWNTGAAWQVT
                     KDVKLRAGVLNLGDKDLSRDDYSYNEDGRRYFMAVDYRF"
     gene            complement(17565..19034)
                     /gene="lysP"
                     /locus_tag="IRB70_001196"
     CDS             complement(17565..19034)
                     /gene="lysP"
                     /locus_tag="IRB70_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-specific permease"
                     /protein_id="HBC0631138.1"
                     /translation="MGSETKTTEAPGLRRELKARHLTMIAIGGSIGTGLFVASGATIS
                     QAGPGGALLSYMLIGLMVYFLMTSLGELAAYMPVSGSFATYGQNYVEEGFGFALGWNY
                     WYNWAVTIAVDLVAAQLVMSWWFPDTPGWIWSALFLGVIFLLNYISVRGFGEAEYWFS
                     LIKVTTVIVFIIVGVLMIIGIFKGAQPAGWSNWTIGEAPFAGGFAAMIGVAMIVGFSF
                     QGTELIGIAAGESEDPAKNIPRAVRQVFWRILLFYVFAILIISLIIPYTDPSLLRNDV
                     KDISVSPFTLVFQHAGLLSAAAVMNAVILTAVLSAGNSGMYASTRMLYTLACDGKAPR
                     IFAKLSRGGVPRNALYATTVIAGLCFLTSMFGNQTVYLWLLNTSGMTGFIAWLGIAIS
                     HYRFRRGYVLQGHDINDLPYRSGFFPLGPIFAFILCLIITLGQNYEAFLKDTIDWGGV
                     AATYIGIPLFLIIWFGYKLIKGTHFVRYSEMKFPQNDKK"
     gene            complement(19239..20120)
                     /locus_tag="IRB70_001197"
     CDS             complement(19239..20120)
                     /locus_tag="IRB70_001197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0631139.1"
                     /translation="MHITLRQLEVFAEVLKSGSTTQASVMLALSQSAVSAALTDLEGQ
                     LGVQLFDRVGKRLVVNEHGRLLYPRALALLEQAVEIEQLFREDNGAIRIYASSTIGNY
                     ILPAVIARYRHDYPQLPIELSVGNSQDVMQAVLDFRVDIGFIEGPCHSTEIISEPWLE
                     DELVVFAAPTSPLARGPVTLEQLAAAPWILRERGSGTREIVDYLLLSHLPKFEMAMEL
                     GNSEAIKHAVRHGLGISCLSRRVIEDQLQAGTLSEVAVPLPRLMRTLWRIHHRQKHLS
                     NALRRFLDYCDPANVPR"
     gene            20219..21268
                     /locus_tag="IRB70_001198"
     CDS             20219..21268
                     /locus_tag="IRB70_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YeiH family protein"
                     /protein_id="HBC0631140.1"
                     /translation="MTNITLQKQHRTLWHFIPGLALSAVITGVALWGGSIPAVAGAGF
                     SALTLAILLGMVLGNTIYPHIWKSCDGGVLFAKQYLLRLGIILYGFRLTFSQIADVGI
                     SGIIIDVLTLSSTFLLACFLGQKVFGLDKHTSWLIGAGSSICGAAAVLATEPVVKAEA
                     SKVTVAVATVVIFGTVAIFLYPAIYPLMSQWFSPETFGIYIGSTVHEVAQVVAAGHAI
                     SPDAENAAVISKMLRVMMLAPFLILLAARVKQLSGANSGEKSKITIPWFAILFIVVAI
                     FNSFHLLPQSVVNMLVTLDTFLLAMAMAALGLTTHVSALKKAGAKPLLMALVLFAWLI
                     VGGGAINYVIQSVIA"
     gene            21342..22199
                     /gene="nfo"
                     /locus_tag="IRB70_001199"
     CDS             21342..22199
                     /gene="nfo"
                     /locus_tag="IRB70_001199"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBC0631141.1"
                     /translation="MKYIGAHVSAAGGLANAAIRAAEIDATAFALFTKNQRQWRAAPL
                     TTQTIDEFKAACEKYHYTSAQILPHDSYLINLGHPVTEALEKSRDAFIDEMQRCEQLG
                     LSLLNFHPGSHLMQISEEDCLARIAESINIALDKTHGVTAVIENTAGQGSNLGFKFEH
                     LAAIIDGVEDKSRVGVCIDTCHAFAAGYDLRTSAECEKTFADFARIVGFKYLRGMHLN
                     DAKSTFGSRVDRHHSLGEGNIGHDAFRWIMQDDRFDGIPLILETINPDIWAEEIAWLK
                     AQQTEKAVA"
     gene            22202..23290
                     /locus_tag="IRB70_001200"
     CDS             22202..23290
                     /locus_tag="IRB70_001200"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBC0631142.1"
                     /translation="MNNREKEILAILRRNPLIQQNEIADMLQISRSRVAAHIMDLMRK
                     GRIKGKGYILTEQEYCVVVGTINMDIRGMADIRYPQAASHPGTIHCSAGGVGRNIAHN
                     LALLGRDVHLLSVIGDDFYGEMLLEETRRAGVNVSGCVRLHGQSTSTYLAIANRDDQT
                     VLAINDTHLLDQLTPQLLNGSRDLLRHAGVVLADCNLTAEALEWVFTLADEIPVFVDT
                     VSEFKAGKIKHWLAHIHTLKPTLPELEILWGQAITSDADRNAAVNALHQQGVQQLFVY
                     LPDESVYCSEKDGEQFLLTAPAHTTVDSFGADDGFMAGLVYSFLEGNNFRDSARFAMA
                     CAAISRASGSLNNPTLSADNALSLVPMV"
     gene            complement(23346..24596)
                     /locus_tag="IRB70_001201"
     CDS             complement(23346..24596)
                     /locus_tag="IRB70_001201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBC0631143.1"
                     /translation="MDVMRSVLGMVVLLAIAFLLSVNKKRISLRTVGAALVLQVVIGG
                     IMLWLPPGRWVAEKVAFGVHKVMAYSDAGSAFIFGSLVGPKMDTLFDGAGFIFGFRVL
                     PAIIFVTALVSILYYIGVMGILIRILGGIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRLNRNELFTAICSGMASIAGSTMIGYAALGVPVEYLLAASLMAIPGGILFAR
                     LLSPATESSQVSFNNLSFTETPPKSIIEAAATGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGVGGWFGFEHASLESILGYLLAPLAWVMGVDWSDANLAGSLIGQKLAINEFVA
                     YLNFSPYLQTAGTLDAKTVAIISFALCGFANFGSIGVVVGAFSAVAPHRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(24696..25637)
                     /gene="rihB"
                     /locus_tag="IRB70_001202"
     CDS             complement(24696..25637)
                     /gene="rihB"
                     /locus_tag="IRB70_001202"
                     /EC_number="3.2.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosylpyrimidine nucleosidase"
                     /protein_id="HBC0631144.1"
                     /translation="MEKRKIILDCDPGHDDAIAMMMAAKHPAIDLLGITIVAGNQTLD
                     KTLINGLNVCQKLEINVPVYAGMSQPIMRQQIVADNIHGETGLDGPVFEPLTRQAENT
                     HAVKYIIDTLMASDGDITLVPVGPLSNIAVAMRMQPAILPKIREIVLMGGAYGTGNFT
                     PSAEFNIFADPEAARVVFTSGVPLVMMGLDLTNQTVCTPDVIARMERAGGPAGELFSD
                     IMNFTLKTQFENYGLAGGPVHDATCIGYLINPDGIKTQEMYVEVDVNSGPCYGRTVCD
                     ELGVLGKPANTKVGITIDTDWFWGLVEECVRGYIKTH"
     gene            25767..26465
                     /gene="yeiL"
                     /locus_tag="IRB70_001203"
     CDS             25767..26465
                     /gene="yeiL"
                     /locus_tag="IRB70_001203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311082.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator YeiL"
                     /protein_id="HBC0631145.1"
                     /translation="MKEIHNNDLKQQLMSESAFKDCFSTDVSADTRLFHFLARDYIVQ
                     EGQQPSWLFYLTRGRARLYATLANGRVSLIDFFAAPCFIGEIELIDKDHEPRAVQAIE
                     ECWCLALPMKHYRPLLLNDTLFLRKLCVTLSHKNYRNIVSLTQNQSFPLVNRLAAFIL
                     LSQEGDLYHEKHTQAAEYLGVTYRHLLYVIAQLIHDGLLIKSKKGYLIKNRKQLSGLA
                     LEMDPENKFSGMMQ"
     gene            complement(26534..27784)
                     /locus_tag="IRB70_001204"
     CDS             complement(26534..27784)
                     /locus_tag="IRB70_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBC0631146.1"
                     /translation="MDIMRSVVGMVVLLAIAFLLSVNKKSISLRTVGAALLLQIAIGG
                     IMLYFPPGKWAVELAALGVHKVMSYSDAGSAFIFGSLVGPKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIGVMGLLIRILGSIFQKALNISKIESFVAVTTIFLGQNEIPAI
                     VKPFIDRMNRNELFTAICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEPSQVTFENLSFSETPPKSFIEAAASGAMTGLKIAAGVATVVMAFVAIIALI
                     NGIIGGIGGWFGFANASLESIFGYVLAPLAWIMGVDWSDANLAGSLIGQKLAINEFVA
                     YLSFSPYLQTGGTLEVKTIAIISFALCGFANFGSIGVVVGAFSAISPKRAPEIAQLGL
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(27878..28816)
                     /gene="psuG"
                     /locus_tag="IRB70_001205"
     CDS             complement(27878..28816)
                     /gene="psuG"
                     /locus_tag="IRB70_001205"
                     /EC_number="4.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HBC0631147.1"
                     /translation="MSELKISPELLQISPEVQDALKNKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKQGAVPATIAIIGGVMKVGLSKEEIELLGREGHNVTKVSRRDLPFV
                     VAAGKNGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELANTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTKALPAFFCRTSPFDVSIRLDSATEIARA
                     MAVKWQTGLNGGLVVANPIPEQFAMPEESINAAIDQAVAEAEEQGVIGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAILASEIAKEYQRLAG"
     gene            complement(28804..29745)
                     /locus_tag="IRB70_001206"
     CDS             complement(28804..29745)
                     /locus_tag="IRB70_001206"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HBC0631148.1"
                     /translation="MREKDYVVIIGSANIDVAGYSHESLNYADSNPGKIKFTPGGVGR
                     NIAQNLALLGNKAWLLSAVGSDFYGQSLLTQTNQSGVYVDKCLIVPGENTSSYLSLLD
                     NTGEMLVAINDMNISNAITAEYLAQHREFIQRAKVIVADCNISEEALAWILDNAANVP
                     VFVDPVSAWKCVKVRDRLNQIHTLKPNRLEAETLSGIALSGREDVAKVAAWFHQHGLN
                     RLVLSMGGDGVYYSDISGESGWSAPIKTNVINVTGAGDAMMAGLASCWVDGMPFAESV
                     RFAQGCSSMALSCEYTNNPDLSIANVISLVENAECLN"
     gene            complement(30169..31860)
                     /gene="fruA"
                     /locus_tag="IRB70_001207"
     CDS             complement(30169..31860)
                     /gene="fruA"
                     /locus_tag="IRB70_001207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIBC"
                     /protein_id="HBC0631149.1"
                     /translation="MKTLLIIDANLGQARAYMAKTLLGAAARKAKLEIIDNPNDAEMA
                     IVLGDSIPNDSALNGKNVWLGDISRAVAHPELFLSEAKGHAKPYTAPVAATAPVAASG
                     PKRVVAVTACPTGVAHTFMAAEAIETEAKKRGWWVKVETRGSVGAGNAITPEEVAAAD
                     LVIVAADIEVDLAKFAGKPMYRTSTGLALKKTAQELDKAVAEATPYEPAGKAQTATTE
                     GKKESAGAYRHLLTGVSYMLPMVVAGGLCIALSFAFGIEAFKEPGTLAAALMQIGGGS
                     AFALMVPVLAGYIAFSIADRPGLTPGLIGGMLAVSTGSGFIGGIIAGFLAGYIAKLIS
                     TQLKLPQSMEALKPILIIPLISSLVVGLAMIYLIGKPVAGILEGLTHWLQTMGTANAV
                     LLGAILGGMMCTDMGGPVNKAAYAFGVGLLSTQTYGPMAAIMAAGMVPPLAMGLATMV
                     ARRKFDKAQQEGGKAALVLGLCFISEGAIPFAARDPMRVLPCCIVGGALTGAISMAIG
                     AKLMAPHGGLFVLLIPGAITPVLGYLVAIIAGTLVAGLAYAFLKRPEVDAVAKAA"
     gene            complement(31877..32815)
                     /gene="fruK"
                     /locus_tag="IRB70_001208"
     CDS             complement(31877..32815)
                     /gene="fruK"
                     /locus_tag="IRB70_001208"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBC0631150.1"
                     /translation="MSRRVATITLNPAYDLVGFCPEIERGEVNLVKTTGLHAAGKGIN
                     VAKVLKDLGIDVTVGGFLGKDNQDGFQQLFSELGIANRFQVVQGRTRINVKLTEKDGE
                     VTDFNFSGFEVTPADWERFVTDSLSWLGQFDMVCVSGSLPSGVSPEAFTDWMTRLRSQ
                     CPCIIFDSSREALVAGLKAAPWLVKPNRRELEIWAGRKLPEMKDVIEAAHALREQGIA
                     HVVISLGAEGALWVNASGEWIAKPPSVDVVSTVGAGDSMVGGLIYGLLMRESSEHTLR
                     LATAVAALAVSQSNVGITDRPQLAAMMARVDLQPFN"
     gene            complement(32815..33945)
                     /gene="fruB"
                     /locus_tag="IRB70_001209"
     CDS             complement(32815..33945)
                     /gene="fruB"
                     /locus_tag="IRB70_001209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fused PTS fructose transporter subunit IIA/HPr
                     protein"
                     /protein_id="HBC0631151.1"
                     /translation="MFQLSVQDIHPGEKAGDKEEAIRQVAAALVQAGNVAEGYVNGML
                     AREQQTSTFLGNGIAIPHGTTDTRDQVLKTGVQVFQFPEGVTWGDGQVAYVAIGIAAS
                     SDEHLGLLRQLTHVLSDDSVAEQLKSATTAEELRALLMGEKQSEQLKLDNEMLTLDIV
                     ASDLLTLQALNAARLKEAGAVDATFVTKAINEQPLNLGQGIWLSDSAEGNLRSAIAVS
                     RAANAFDVDGETAAMLVSVAMNDDQPVAVLKRLADLLLDNKADRLLKADAATLLALLT
                     SDDAPTDDVLSAEFVVRNEHGLHARPGTMLVNTIKQFNSDITVTNLDGTGKPANGRSL
                     MKVVALGVKKGHRLRFTAQGADAEQALKAIGDAIAAGLGEGA"
     gene            34313..35494
                     /gene="setB"
                     /locus_tag="IRB70_001210"
     CDS             34313..35494
                     /gene="setB"
                     /locus_tag="IRB70_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter SetB"
                     /protein_id="HBC0631152.1"
                     /translation="MHNSPAVSSAKSFDLTSTAFLIVAFLTGIAGALQTPTLSIFLTD
                     EVHARPAMVGFFFTGSAVIGILVSQFLAGRSDKRGDRKSLIVFCCLLGVLACTLFAWN
                     RNYFVLLFVGVFLSSFGSTANPQMFALAREHADKTGREAVMFSSFLRAQVSLAWVIGP
                     PLAYALAMGFSFTVMYLSAAVAFIVCGVMVWLFLPSMQKELPLATGTVEAPRRNRRDT
                     LLLFVICTLMWGSNSLYIINMPLFIINELHLPEKLAGVMMGTAAGLEIPTMLIAGYFA
                     KRLGKRFLMRVAAVGGVCFYAGMLMAHSPAILLGLQLLNAIFIGILGGIGMLYFQDLM
                     PGQAGSATTLYTNTSRVGWIIAGSVAGIVAEIWNYHAVFWFAMVMIIATLFCLLRIKD
                     V"
     gene            complement(35491..35745)
                     /locus_tag="IRB70_001211"
     CDS             complement(35491..35745)
                     /locus_tag="IRB70_001211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBC0631153.1"
                     /translation="MECRPGCGACCTAPSISSPIPGMPDGKPANTPCIQLDEQQRCKI
                     FTSPLRPKVCAGLQASAEMCGNSRQQAMTWLIDLEMLTAP"
     gene            35900..36472
                     /gene="yeiP"
                     /locus_tag="IRB70_001212"
     CDS             35900..36472
                     /gene="yeiP"
                     /locus_tag="IRB70_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007750416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P-like protein YeiP"
                     /protein_id="HBC0631154.1"
                     /translation="MPRANEIKKGMVLNYNGKLLLVKDIDIQSPTARGAATLYKMRFS
                     DVRTGLKVEERFKGDDIVDTVTLTRRYVDFSYVDGNEYVFMDKEDYTPYTFTKDQIEE
                     ELLFMPEGGMPDMQVLTWDGQLLALELPQTVDLEIVETAPGIKGASASARNKPATLST
                     GLVIQVPEYLSPGEKIRIHIEERRYMGRAD"
     gene            36695..38161
                     /locus_tag="IRB70_001213"
     CDS             36695..38161
                     /locus_tag="IRB70_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBC0631155.1"
                     /translation="MNTIASVTLPHHVHAPRYDRQQLQSRIVHFGFGAFHRAHQALLT
                     DRVLNAQGGDWGICEISLFSGDQLMSQLRAQNHLYTVLEKGADGNQAIIVGAVHDCLN
                     AKLDSLAAIIEKFCEPQVAIVSLTITEKGYCIDPATGALDTSNPRIIHDLQNPEEPHS
                     APGILVEALKRRRERGLAPFTVLSCDNIPDNGHVVKNAVLGMAEKRSPELAGWIKEHV
                     SFPGTMVDRIVPAATDESLAEISQHLGVNDPCAISCEPFIQWVVEDNFVAGRPAWEVA
                     GVQMVNDVLPWEEMKLRMLNGSHSFLAYLGYLSGFAHISDCMQDRAFRHAARTLMLDE
                     QAPTLRIKDVDLTQYADKLIARFANPALKHKTWQIAMDGSQKLPQRMLAGIRIHLARE
                     TDWSLLALGVAGWMRYVSGVDDAGNAIDVRDPLSDKICELVAGSNSEQRVTALLSLRE
                     VFGDDLPDNPHFVQAIEQAWQQIAQFGAHQALLNTLKI"
     gene            38279..39265
                     /gene="yeiR"
                     /locus_tag="IRB70_001214"
     CDS             38279..39265
                     /gene="yeiR"
                     /locus_tag="IRB70_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding GTPase YeiR"
                     /protein_id="HBC0631156.1"
                     /translation="MTRTNLITGFLGSGKTTSILHLLAHKDPNEKWAVLVNEFGEVGI
                     DGALLADSGALLKEIPGGCMCCVNGLPMQVGLNTLLRQGKPDRLLIEPTGLGHPKQIL
                     DLLTAPVYEPWIDLRATLCILDPRLLLDEKSASNENFRDQLAAADIIVANKSDRATPE
                     SEQALQRWWQQNGGDRQLIHSEHGKVDGHLLDLPRRNLAELPASAAHSHQHVVKKGLA
                     ALSLPEHQRWRRSLNSGQGYQACGWIFDADTVFDTIGILEWARLAPVERVKGVLRIPE
                     GLVRINRQGDDLHIETQNVAPPDSRIELISSSEADWNALQSALLKLRLATTA"
     gene            39304..40017
                     /gene="lpxT"
                     /locus_tag="IRB70_001215"
     CDS             39304..40017
                     /gene="lpxT"
                     /locus_tag="IRB70_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Kdo(2)-lipid A phosphotransferase"
                     /protein_id="HBC0631157.1"
                     /translation="MIKNLPQIVLLNIVGLALFLSWYIPVNHGFWLPIDADIFYFFNQ
                     KLVESKAFLWLVALTNNRAFDGCSLLAMGMLMLSFWLKENAPGRRRIVIIGLVMLLTA
                     VVLNQLGQALIPVKRASPTLTFTDINRVSELLSVPTKDASRDSFPGDHGMMLLIFSAF
                     MWRYFGKVAGLIALIIFVVFAFPRVMIGAHWFTDIIVGSMTVILIGLPWVLLTPLSDR
                     LITFFDKSLPGKNKHFQNK"
     gene            40429..40995
                     /gene="mepS"
                     /locus_tag="IRB70_001216"
     CDS             40429..40995
                     /gene="mepS"
                     /locus_tag="IRB70_001216"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional murein DD-endopeptidase/murein
                     LD-carboxypeptidase"
                     /protein_id="HBC0631158.1"
                     /translation="MVKSQPILRYILRGIPAIAVAVLLSACSANNTAKNMHPETRAVG
                     SETSSLQASQDEFENLVRNVDVKSRIMDQYADWKGVRYRLGGSTKKGIDCSGFVQRTF
                     REQFGLELPRSTYEQQEMGKSVSRSNLRTGDLVLFRAGSTGRHVGIYIGNNQFVHAST
                     SSGVIISSMNEPYWKKRYNEARRVLSRS"
     gene            41176..42732
                     /locus_tag="IRB70_001217"
     CDS             41176..42732
                     /locus_tag="IRB70_001217"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic di-GMP phosphodiesterase"
                     /protein_id="HBC0631159.1"
                     /translation="MFIRAPNSGRKLLLTCIVAGVMIAILVSCLQFLVAWHKHEVKYD
                     TLITDVQKYLDTYFADLKSTTDRLQPLTLDTCQQANPELTARAAFSMNVRTFVLVKDK
                     KTFCSSATGEMDIPLKELIPALDINKNVDMAILPGTPMVPNKPAIVIWYRNPLLKNSG
                     VFAALNLNLTPSLFYSSRQEDYDGVALIIGNTALSTFSSRLMNVNELTDMPVRETKIA
                     GIPLTVRLYADDWTWNDVWYAFLLGGMSGTFVGLLCYYLMSVRMRPGREIMTAIKREQ
                     FYVVYQPVVDTQALRVTGLEVLLRWRHPVAGEIPPDAFINFAEAQKMIVPLTQHLFEL
                     IARDAAELEKVLPVGVKFGINIAPAHLHSESFKADIQKLLTSLPAHHFQIVLEITERD
                     MLKEREATQLFAWLHSVGVEIAIDDFGTGHSALIYLERFTLDYLKIDRGFINAIGTET
                     ITSPVLDAVLTLAKRLNMLTVAEGVETPEQARWLSERGVNFMQGYWISRPLPLDDFVR
                     WLKKPYTPQW"
     gene            42814..44628
                     /locus_tag="IRB70_001218"
     CDS             42814..44628
                     /locus_tag="IRB70_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311096.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBC0631160.1"
                     /translation="MIVRILLLFIALFTFGAQAQAIKESYAFAVLGEPRYAFNFNHFD
                     YVNPAAPKGGQITLSALGTFDNFNRYALRGNPGARTEQLYDTLFTTSDDEPGSYYPLI
                     AESARYADDYSWVEVAINPRARFHDGSPITARDVEFTFQKFMTEGVPQFRLVYKGTTV
                     KAIAPLTVRIELAKPGKEDMLSLFSLPVFPEKYWKDHKLSDPLATPPLASGPYRITSW
                     KMGQNIVYSRVKDYWAANLPVNRGRWNFDTIRYDYYLDDNVAFEAFKAGAFDLRMEND
                     AKNWATRYTGKNFDKKYIIKDEQKNESAQDTRWLAFNIQRPVFSDRRVREAITLAFDF
                     EWMNKALFYTAWSRTNSYFQNTEYAARNYPDAAELVLLAPMKKDLPPEVFTQIYQPPV
                     SKGDGYDRDNLLKADKLLNEAGWVLKGQQRVNATTGQPLSFELLLPASSNSQWVLPFQ
                     HSLQRLGINMDIRKVDNSQITNRMRSRDYDMMPRVWRAMPWPSSDLQISWSSEYINST
                     YNAPGVQSPVIDSLINQIIAAQGNKEKLLPLGRALDRVLTWNYYMLPMWYMAEDRLAW
                     WDKFSQPAVRPVYSLGIDTWWYDVNKAAKLPSARQQGE"
     gene            44629..45723
                     /locus_tag="IRB70_001219"
     CDS             44629..45723
                     /locus_tag="IRB70_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter permease YejB"
                     /protein_id="HBC0631161.1"
                     /translation="MGAYLIRRLLLVIPTLWAIITINFFIVQIAPGGPVDQAIAAIEF
                     GNTGVLPGAGGEGVRASHAQTGVGNISDSNYRGGRGLDPEVIAEITHRYGFDKPIHER
                     YFKMLWDYIRFDFGDSLFRSASVLTLIKDSLPVSITLGLWSTLIIYLVSIPLGIRKAV
                     YNGSRFDVWSSAFIIIGYAIPAFLFAILLIVFFAGGSYFDLFPLRGLVSANFDSLPWY
                     QKITDYLWHITLPVLATVIGGFAALTMLTKNSFLDEVRKQYVVTARAKGVSEKNILWK
                     HVFRNAMLLVIAGFPATFISMFFTGSLLIEVMFSLNGLGLLGYEATVSRDYPVMFGTL
                     YIFTLIGLLLNIVSDISYTLVDPRIDFEGR"
     gene            45723..46748
                     /locus_tag="IRB70_001220"
     CDS             45723..46748
                     /locus_tag="IRB70_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0631162.1"
                     /translation="MSRLSPVNQARWARFRHNRRGYWSLWIFLVLFGLSLCSELIAND
                     KPLLVRYDGSWYFPLLKNYSESDFGGPLASQADYQDPWLKQRLEDKGWVLWAPIRFGA
                     TSINFATDKPFPSPPSRQNWLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVL
                     AGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQPNFWWLLAITVLFGWMSL
                     VGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTL
                     TSLDFLGFGLPLGSPSLGELLLQGKNNLQAPWLGITAFLSVAILLSLLIFIGEAVRDA
                     FDPNKAV"
     gene            46750..48339
                     /gene="yejF"
                     /locus_tag="IRB70_001221"
     CDS             46750..48339
                     /gene="yejF"
                     /locus_tag="IRB70_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin C ABC transporter ATP-binding protein
                     YejF"
                     /protein_id="HBC0631163.1"
                     /translation="MTQTLLAIENLSVGFRHQQTVRTVVNDVSLQIEAGETLALVGES
                     GSGKSVTALSILRLLPSPPVEYLSGDIRFHGESLLHASDQTLRGVRGNKIAMIFQEPM
                     VSLNPLHTLEKQLYEVLSLHRGMRREAARGEILNCLDRVGIRQAAKRLTDYPHQLSGG
                     ERQRVMIAMALLTRPELLIADEPTTALDVSVQAQILQLLRELQGELNMGMLFITHNLS
                     IVRKLAHRVAVMHNGRCVEQNNAATLFASPTHPYTQKLLNSEPSGDPVPLPEPASTLL
                     DVEQLQVAFPIRKGILKRIVDHNVVVKNISFTLRAGETLGLVGESGSGKSTTGLALLR
                     LINSQGSIVFDGQPLQNLNRRQLLPIRHRIQVVFQDPNSSLNPRLNVLQIIEEGLRVH
                     QPTLSVAQREQQVIAVMHEVGLDPETRHRYPAEFSGGQRQRIAIARALILKPSLIILD
                     EPTSSLDKTVQAQILTLLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQG
                     PCARVFAAPQQEYTRQLLALS"
     gene            complement(48343..48687)
                     /locus_tag="IRB70_001222"
     CDS             complement(48343..48687)
                     /locus_tag="IRB70_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631164.1"
                     /translation="MTSLQLSIVHRLPQNYRWSAGFAGSKVEPIPQNGPCGDNSLVAL
                     KLLSPDGDNAWSVMYKLSQALSDIEVPCSVLECEGEPCLFVNRQDEFAATCRLKNFGV
                     AIAEPFSNYNPF"
     gene            complement(49020..50210)
                     /gene="bcr"
                     /locus_tag="IRB70_001223"
     CDS             complement(49020..50210)
                     /gene="bcr"
                     /locus_tag="IRB70_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter Bcr"
                     /protein_id="HBC0631165.1"
                     /translation="MTTRQHSSFAIVFILGLLAMLMPLSIDMYLPALPVISAQFGVPA
                     GSTQMTLSTYILGFALGQLIYGPMADSFGRKPVVLGGTLVFAAAAVACALAQTIDQLI
                     VMRFFHGLAAAAASVVINALMRDIYPKEEFSRMMSFVMLVTTIAPLMAPIVGGWVLVW
                     LSWHYIFWILAVAAILASAMIFFLIKETLPPERRQPFHIRTTIGNFAALFRHKRVLSY
                     MLASGFSFAGMFSFLSAGPFVYIEINHVAPENFGYYFALNIVFLFVMTIFNSRFVRRI
                     GALNMFRSGLWIQFIMAAWMVISALLGLGFWSLVVGVAAFVGCVSMVSSNAMAVILDE
                     FPHMAGTASSLAGTFRFGIGAIVGALLSLATFNSAWPMIWSIAFCATSSILFCLYASR
                     PKKR"
     gene            complement(50238..50933)
                     /gene="rsuA"
                     /locus_tag="IRB70_001224"
     CDS             complement(50238..50933)
                     /gene="rsuA"
                     /locus_tag="IRB70_001224"
                     /EC_number="5.4.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA pseudouridine(516) synthase RsuA"
                     /protein_id="HBC0631166.1"
                     /translation="MRLDKFIAQQLGVSRAIAGREIRGNRVTVDGEIVRNAAFKLLPE
                     HDVAYDGNPLAQQHGPRYFMLNKPQGYVCSTDDPDHPTVLYFLDEPVAWKLHAAGRLD
                     IDTTGLVLMTDDGQWSHRITSPRHHCEKTYLVTLESPVADDTAEQFAKGVQLHNEKDL
                     TKPAVLEVITPTQVRLTISEGRYHQVKRMFAAVGNHVVELHRERIGGITLDADLAPGE
                     YRPLTEEEIASVV"
     gene            51083..52843
                     /locus_tag="IRB70_001225"
     CDS             51083..52843
                     /locus_tag="IRB70_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBC0631167.1"
                     /translation="MIFTLRPYQQEAVDATLNHFRRHKTPAVIVLPTGAGKSLVIAEL
                     ARLARGRVLVLAHVKELVAQNHAKYQALGLEADIFAAGLKRKESHGKVVFGSIQSVAR
                     NLDAFQGEFSLLIVDECHRIGDDEESQYQQILTHLTKVNPHLRLLGLTATPFRLGKGW
                     IYQFHYHGMVRGDEKALFRDCIYELPLRYMIKHGYLTPPERLDMPVVQYDFSRLQAQS
                     NGLFSEADLNRELKKQQRITPHIISQIMEFAATRKGVMIFAATVEHAKEIVGLLPTED
                     AALITGDTPGAERDVLIENFKAQRFRYLVNVAVLTTGFDAPHVDLIAILRPTESVSLY
                     QQIVGRGLRLAPGKTDCLILDYAGNPHDLYAPEVGTPKGKSDNVPVQVFCPACGFANT
                     FWGKTTADGTLIEHFGRRCQGWFEDDDGHREQCDFRFRFKNCPQCNAENDIAARRCRE
                     CDTVLVDPDDMLKAALRLKDALVLRCSGMSLQHGHDEKGEWLKITYYDEDGADVSERF
                     RLQTPAQRTAFEQLFIRPHTRTPGIPLRWITAADVLAQQALLRHPDFVVARMKGQYWQ
                     VREKVFDYEGRFRRAHELRG"
     gene            52968..53252
                     /gene="rplY"
                     /locus_tag="IRB70_001226"
     CDS             52968..53252
                     /gene="rplY"
                     /locus_tag="IRB70_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25"
                     /protein_id="HBC0631168.1"
                     /translation="MFTINAEVRKEQGKGASRRLRAANKFPAIIYGGKEAPLAVELDH
                     DKVMNMQVKAEFYSEVLTIVVDGKEIKVKAQDVQRHPYKPKLLHIDFVRA"
     gene            complement(53391..54398)
                     /gene="yejK"
                     /locus_tag="IRB70_001227"
     CDS             complement(53391..54398)
                     /gene="yejK"
                     /locus_tag="IRB70_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein YejK"
                     /protein_id="HBC0631169.1"
                     /translation="MSLDINQIALHQLIKRDEQNLELVLRDSLLEPTETVVEMVAELH
                     RVYSAKNKAYGLFSEESELAQTLRLQRQGEEDFLAFSRAATGRLRDELAKYPFADGGF
                     VLFCHYRYLAVEYLLVAVLSNLSSMRVNENLDINPTHYLDINHADIVARIDLTEWETN
                     PESTRYLTFLKGRVGRKVADFFMDFLGASEGLNAKAQNRGLLQAVDDFTAEAQLDKAE
                     RQNVRQQVYSYCNEQLQAGEEIELESLSKELAGVSEVSFTEFAAEKGYELEESFPADR
                     STLRQLTKFAGSGGGLTINFDAMLLGERIFWDPATDTLTIKGTPPNLRDQLQRRTSGG
                     N"
     gene            54580..54807
                     /locus_tag="IRB70_001228"
     CDS             54580..54807
                     /locus_tag="IRB70_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YejL family protein"
                     /protein_id="HBC0631170.1"
                     /translation="MPQISRYSDEQVEQLLAELLNILEKHKAPTDLSLMVLGNMVTNL
                     INTSIAPAQRQAIANSFARALQSSINEDKAH"
     gene            54827..56587
                     /gene="pbgA"
                     /locus_tag="IRB70_001229"
     CDS             54827..56587
                     /gene="pbgA"
                     /locus_tag="IRB70_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin transport protein PbgA"
                     /protein_id="HBC0631171.1"
                     /translation="MVTHRQRYREKVSQMVSWGHWFALFNILLSLVIGSRYLFIADWP
                     TTLAGRIYSYVSIIGHFSFLVFATYLLILFPLTFIVGSQRLMRFLSVILATAGMTLLL
                     IDSEVFTRFHLHLNPIVWQLVINPDENEMARDWQLMFISVPVILLLELVFATWSWQKL
                     RSLTRRRRFARPLAAFLFIAFIASHVVYIWADANFYRPITMQRANLPLSYPMTARRFL
                     EKHGLLDAQEYQRRLIEQGNPDAVSVQYPLSELRYRDMGTGQNVLLITVDGLNYSRFE
                     KQMPALAGFAEQNISFTRHMSSGNTTDNGIFGLFYGISPSYMDGILSTRTPAALITAL
                     NQQGYQLGLFSSDGFTSPLYRQALLSDFSMPSVRTQSDEQTATQWINWLGRYAQEDNR
                     WFSWVSFNGTNIDDSNQQAFARKYSRAAGNVDDQINRVLNALRDSGKLDNTVVIITAG
                     RGIPLSEEEETFDWSHGHLQVPLVIHWPGTPAQRINALTDHTDLMTTLMQRLLHVSTP
                     ASEYSQGQDLFNPQRRHYWVTAADNDTLAITTPKKTLVLNNNGKYRTYNLRGERVKDE
                     KPQLSLLLQVLTDEKRFIAN"
     gene            56662..56738
                     /locus_tag="IRB70_001230"
     tRNA            56662..56738
                     /locus_tag="IRB70_001230"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:56696..56698,aa:Pro,seq:ggg)
     gene            complement(56841..59432)
                     /gene="yejO"
                     /locus_tag="IRB70_001231"
     CDS             complement(56841..59432)
                     /gene="yejO"
                     /locus_tag="IRB70_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311108.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter YejO"
                     /protein_id="HBC0631172.1"
                     /translation="MHQSGSVSLCRSAISVLVATALYSPIALASTVEYGETVDGVVLE
                     KDIQLVYGTANNTKINPGGEQHIKEFGISSNTEINGGYQYIEMNGTAEYSVLNDGYQI
                     VQMGGAANQTTLNNGVLQVYGAANEPTIKGGRLIVEKDGGTVFAAIEKGGLLEVKEGG
                     FALAVDQKAGGAIKTTTRAMEVFGTNRLGQFDIKNGIANNMLLENGGSLRVEENDFAY
                     NTTVDNGGLLEVMDGGTATGVDKKAGGKLIVSTNALEVSGTNSKGQFSIKDGVSKNYE
                     LDDGSGLIVMEDTQAIDTILDEHATMQSLGKDTGTRVQANAVYDLGRSDQNGSITYSS
                     KAISENMVINNGRANVWAGTMVNVSVRGNDGILEVMKPQINYAPAMLVGSVVVSEGAS
                     LRTHGAVDTSKADVSLDGSSWTIIADITTTNQNTLLNLANLAMSDANVIMMDEPVTRS
                     SVTASAENFITLTTNTLSGNGNFYMRTDMANHQSDQLNVTGQATGDFKIFVTDTGASP
                     AAGDSLTLVTTGGGDAAFTLGNAGGVVDIGTYEYTLLDNGNHSWSLAENRAQITPSTT
                     DVLNMAAAQPLVFDAELDTVRERLGSVKGVNYDTAMWSSAINTRNNVTTDAGAGFEQT
                     LTGLTLGIDSRFSREESSTIRGLFFGYSHSDIGFDRGGKGNVDSYTLGAYAGWEHQNG
                     AYVDGVVKVDRFANTIHGKMSNGATAFGDYNSNGAGAHVESGFRWVDGLWSVRPYLAF
                     TGFTTDGQDYTLSNGMRADVGNTRILRAEAGTAVSYHMDLQNGTTLEPWLKAAVRQEY
                     ADSNQVKVNDDGKFNNDVAGTRGVYQAGIRSSFTPTLSGHLSVSYGNGAGVESPWNTQ
                     AGVVWTF"
     gene            59752..60399
                     /gene="narP"
                     /locus_tag="IRB70_001232"
     CDS             59752..60399
                     /gene="narP"
                     /locus_tag="IRB70_001232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite response regulator protein NarP"
                     /protein_id="HBC0631173.1"
                     /translation="MPEATPFQVMIVDDHPLMRRGVRQLLELDPGFEVVAEAGDGASA
                     IDLANRLDIDVILLDLNMKGMSGLDTLNALRRDGVTAQIIILTVSDASSDVFALIDAG
                     ADGYLLKDSDPEVLLEAIRAGAKGSKVFSERVNQYLREREMFGAEEDPFSVLTERELD
                     VLHELAQGLSNKQIASVLNISEQTVKVHIRNLLRKLNVRSRVAATILFLQQRGAQ"
     gene            complement(60434..61486)
                     /gene="ccmH"
                     /locus_tag="IRB70_001233"
     CDS             complement(60434..61486)
                     /gene="ccmH"
                     /locus_tag="IRB70_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis thiol:disulfide
                     oxidoreductase CcmH"
                     /protein_id="HBC0631174.1"
                     /translation="MRFLLGVLMLMISGSALATIDVLQFKDEAQEQQFRQLTEELRCP
                     KCQNNSIADSNSMIATDLRQKVYELMQEGKSKKEIVDYMVARYGNFVTYDPPLTPLTV
                     LLWVLPVVAIGIGGWVIYARSRRRVRVVPEEFPEQSVPEGKRAGYIVYLPGIVVALIV
                     AGVSYYQTGNYQQVKIWQQATAQAPALLDRALDPKADPLNEEEMSRLALGMRTQLQKN
                     PGDIEGWIMLGRVGMALGNASIATDAYATAYRLDPKNSDAALGYAEALTRSSDPNDNR
                     LGGELLRQLVRTDHSNIRVLSMYAFNAFEQQRFGEAVAAWEMMLKLLPANDTRRAVIE
                     RSIAQAMQHLSPQESK"
     gene            complement(61483..62040)
                     /gene="dsbE"
                     /locus_tag="IRB70_001234"
     CDS             complement(61483..62040)
                     /gene="dsbE"
                     /locus_tag="IRB70_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbE"
                     /protein_id="HBC0631175.1"
                     /translation="MKRKVLLIPLIIFLAIAAALLWQLARNAEGDDPTNLESALIGKP
                     VPKFRLESLDNPGQFYQADVLTQGKPVLLNVWATWCPTCRAEHQYLNQLSAQGIRVVG
                     MNYKDDRQKAISWLKELGNPYALSLFDGDGMLGLDLGVYGAPETFLIDGNGIIRYRHA
                     GDLNPRVWEEEIKPLWEKYSKEAAQ"
BASE COUNT        15254 a        16237 c        15184 g        15432 t
ORIGIN      
        1 gcacgctcct tgcgccaatg gcaatatgtg gcttagctca tgaaaggagc gcaacaagat
       61 gatgaagcta aataagcgat tcattgtctc agataagctg cgattccact attatcgcag
      121 cttatcgata tcaattgcct gaatagccct tgcaatatca ggggaattat tcaacatccg
      181 aacatgctga aataattctg ttgcttcatc gtattcttta cgcaaataac tcaaccactg
      241 tttaatccgc gctacgtgat ataacccggt atcgccctgc ttttccagac gggtatattt
      301 ttgcagcaaa gcaactacct ccggccatgg cattcgcggt tcgttatatt ttaccacccg
      361 gctcaggttg ggaatattga gcgccccgcg accaatcatc actgcgtcgc atccgctgat
      421 cgtcatgcat tgttgcgcac tctgccagtc ccagatttca ccgttggcaa tcaccggaat
      481 attcagccgc tggcgaatct cgccaatcgc ctgccagtca atatgctccg cgcggtaacc
      541 ctgctctttt gtccgcccat gtactaccag ctccgtagcg ccagcctgtt gcaccgcatc
      601 ggcgatttca aatttcttct caccgctgtc ccagcccaga cgcactttta cgctgacggg
      661 caaatgcgcc ggtacagctt cgcgcatcgc ttttgcaccc tgatagatga gttcaggatc
      721 tttgagtaac gtcgccccac cgccgctacc gttaaccgtt ttcgacgggc agccgcaatt
      781 gagatccacg ccccaggaac ctaactcgac cgcacgggcg gcattctctg ccagccattg
      841 tgggaactga cctaacaact gcacgcgcac cagcgtacca gatggtgtcc ggctggcgtt
      901 ttgtagctca gggcaaatgc gatgaaagac ttttaccggc agcagttgat ccaccacgcg
      961 gacaaactcg gtgatgcaca gatcgtagtc gttaacttcg gtcagtaatt cccgcaccag
     1021 agagtcaagt acaccctcca tcggagccag taacacacgc atatcatcac ccgcaaaaaa
     1081 atgaggcgct atgttagcgc ctatggtcag cggattaaag gtctgcaaag agggattgct
     1141 gcaaactgca atccctctct atgcttgatg tatgcctgag ttcgctgctc attgcgtaat
     1201 gcccgggagc gaaaaaataa gcgctgattt cttaatgtga tcggtagcac gttttacgaa
     1261 ttaattgtat gatgaatcca tctcatctgg ggtgttgatt atgagtaaga cactgaacat
     1321 tatctggcaa tatttacgcg ctttcgtcct gatttatgcc tgcctgtatg caggcatttt
     1381 cattgcttcc ctgctaccgg taaccattcc gggcagcatc atcgggatgc tgatcctgtt
     1441 tgtcctgctg gccttgcaaa ttcttccggc aaaatgggtc aatccggggt gctacgtact
     1501 gattcgctat atggcgctat tgtttgtgcc gattggcgta ggcgtcatgc aatattttga
     1561 tttgctccgc gcacagtttg gcccggtagt ggtttcctgt gcagtcagta cgctggtggt
     1621 ttttctggtg gtgagctgga gttcgcaact ggtgcatggt gaacgtaaag tcgtaggtca
     1681 gaaaggatca gaagaatgat ggcgaatatc tggtggtcat taccgctgac gttgattgtc
     1741 ttttttgccg cccgcaaact ggcggcacgg tataagtttc ccctgcttaa cccgttgctg
     1801 gtagcaatgg tggtgatcat tcctttttta atgctgaccg gcatctctta cgacagctac
     1861 tttaaaggta gcgaagtgct aaacgatctg ctgcaaccgg cggtcgttgc gctggcctat
     1921 cctttatatg agcagctaca ccagatccgc gcgcgctgga aatcgatcat caccatctgt
     1981 tttatcggca gcgtggttgc gatggtgacg gggacttccg tggcattgtt gatgggcgct
     2041 tcaccggaaa tcgccgcgtc aatcctgccg aaatcagtca ccacgcctat tgcaatggcg
     2101 gttggcggca gtattggcgg tattccggca atcagcgcag tttgcgtgat tttcgtcggt
     2161 attctgggcg ctgtgtttgg ccatacattg cttaatgcga tgcgtattcg taccaaagct
     2221 gcgcgcggtc tggcaatggg gacagcctcg cacgccctcg gtacggcgcg ctgcgccgag
     2281 ctggattatc aggaaggtgc atttagttcg ctggcgctgg tgttatgcgg gattattact
     2341 tcgctgatcg caccgttcct tttcccgatt attctggcag taatgggcta aaatttgcga
     2401 tgcgtcgcgc atttttgatg taagtttcac gcgttgcata attaatgaga ttcagatcac
     2461 atataaagcc ataacgggtt cgtaaactgt tatcccatta catgattatg aggcaacgcc
     2521 atgcatccac gttttcaaac cgcttttgcc caacttgcgg ataacttgca atctgcactg
     2581 gaacctattc tggcagacaa gtacttcccc gctttgttga ccggggagca agtctcatcg
     2641 ctgaagagcg caacggggct ggacgaagac gcgctggcat tcgcactact tccgctggcg
     2701 gcggcctgtg cgcgtacgcc attgtcgaat tttaatgttg gcgcaattgc gcgcggtgtg
     2761 agcggaacct ggtattttgg tgccaatatg gaatttattg gtgcgacaat gcagcaaacc
     2821 gttcatgccg aacaaagcgc gattagccac gcctggttga gtggtgaaaa agcgcttgca
     2881 gccatcaccg ttaactacac gccttgtggt cactgccgtc agtttatgaa tgaactaaac
     2941 agcggtctgg atctgcgtat tcatctgccg ggccgcgagg cacacgcgct gcgtgactat
     3001 ctaccggatg cctttgggcc gaaagatctg gagattaaaa cgctgctgat ggacgagcag
     3061 gatcacggct atgcgctgac tggtgatgcg ctttctcagg cggcgattgc ggcggcaaac
     3121 cgttcgcaca tgccttacag taagtcgcca agcggtgtcg cgctggaatg taaagacggt
     3181 cgtattttca gcggcagtta cgctgaaaac gccgcattca acccgactct gccgccgttg
     3241 cagggagcgt taattctatt gaatctcaag ggttatgatt acccggatat ccagcgcgcg
     3301 gttctggcag aaaaagccga tgcgccgttg attcagtggg atgccacctc cgcaacgctg
     3361 aaagctctcg gctgtcacaa tatcgaccgc gtgcttctcg cttaagcctg gtgccggatg
     3421 cggcgtgaac gccttatccg gcttgcctgc tctctcccgg tgtcgaaaat cacggcaaac
     3481 agtttgccgt ttcttgcgca aaaccagcgg gtaaagtagc ctgatggaaa ttttccttag
     3541 atcgagtctc ctgcatgtta aagcgcgtgt tcctcagcct gttagtcctg atcggcttgc
     3601 tgctgttgac tgtgctcggc ctcgatcgct ggatgagctg gaaaaccgcg ccttatatct
     3661 acgacgaatt gcaggatctc ccctatcgcc aggtcggcgt ggtgctcggc acagcaaaat
     3721 attatcgtac tggcgtaatt aatcagtatt atcgctaccg cattcaagga gcgattaatg
     3781 cctataacag cggtaaggta aattatctat tactgagcgg cgataacgca ttgcaaagtt
     3841 ataatgagcc gatgaccatg cgcaaagatt taatcgcagc tggtgtcgac ccatcagata
     3901 ttgttctcga ttacgcaggc tttcgtacgc tggattccat cgtgcgtaca cgcaaagttt
     3961 tcgatactaa tgatttcatt attatcaccc aacgtttcca ctgtgagcgg gcattattta
     4021 ttgcgctgca tatggggatt caggctcagt gttatgccgt accgtcaccg aaagatatgc
     4081 tgtcagtacg tattcgcgaa tttgccgccc gtttcggtgc gctggctgac ctttatattt
     4141 ttaaacgtga accgcgtttt ttagggccgc tggtccctat tccggctatg caccaggtgc
     4201 cggaagatgc gcaggggtat cccgccgtca cacccgaaca gttacttgaa ttacaaaaga
     4261 aacaaggaaa gtagttatgg atgtacagca gttttttgtc gttgccgttt ttttccttat
     4321 cccgatattt tgtttccgcg aagcatggaa aggctggcgc gcaggcgcga ttgataaacg
     4381 ggttaaaaat gcaccggaac cggtgtatgt ctggcgagcg aaaaatcccg gactcttctt
     4441 cgcttatatg gtggcatata tcggcttcgg aattttatct atcggcatga ttgtttatct
     4501 tattttctat cgttgatatt ttcccttttc tgttaattat tgagaataat tattacttca
     4561 cttaataagc tgcggatata acattctgaa ccgcagctat ttgtgaatcc tttcacagtt
     4621 taaatttccc cacgcgcata gccttaatat cagcacgcaa tatttattta gcgttcgcct
     4681 taattactca tagcattaag gaagatcaca tgccgcaaca aaattatctg gatgaactca
     4741 ctccggcttt tacgccttta ctggcgatta aagaagcctc tcgctgttta ttatgtcatg
     4801 acgccccctg tagtcaggct tgcccggcac agaccgatcc agggaaattt atccgctcaa
     4861 tttattttcg taattttaaa ggtgctgccg agacgattcg cgaaaataat gctttaggtg
     4921 ctgtatgcgc cagagtgtgc ccgacggaga aattatgcca aagcggttgt acccgtgccg
     4981 gtgttgatac tcccattgat atcggtcgct tacagcgttt tgttactgat tttgaacaac
     5041 aaactgggat ggaaatttat cagcccggta ctaaaacgct cggcaaagtc gcgattattg
     5101 gcgcgggtcc tgccggattg caggccagtg tgacactgac aaaccagggt tatgacgtca
     5161 cgatctatga gaaagaagca caacccggtg gctggttgcg taacggcatt ccgcaattcc
     5221 ggttaccgca atcagtactg gatgcagaaa tcgcccgtat tgaaaaaatg ggcgtgacca
     5281 ttaaatgcaa taacgaaatc ggtaacacac tcaccctgga gcagctgaaa gcggaaaacc
     5341 gcgcggtact ggtcaccgtg gggttatcga gcggttcggg gctaccactg tttgagcata
     5401 gcgacgttga gattgccgtc gacttcctgc aacgtgcacg acaggcgcaa ggcgatatca
     5461 gcattccaca aagcgcatta attatcggcg gcggtgatgt cgcgatggac gtagccagca
     5521 cgctgaaagt tctcggctgt caggcagtaa cttgcgtagc gcgtgaagag ttagatgagt
     5581 ttccggcaag cgaaaaagag tttgccagcg cccgggagct gggcgtttcg atcattgatg
     5641 gattcacgcc agtagccgtg gaaggcaata aagtcacgtt taagcatgta cggttaccgg
     5701 gcgaactgac gatggcggca gataaaatta ttctcgccgt cggtcagcat gccagactgg
     5761 atgcctttgc ggagttagag ccgcagcgta acaccatcaa tacacaaaat taccagaccc
     5821 gcgatccgca agtctttgct gctggcgata ttgttgaggg ggacaaaacc gtggtctatg
     5881 ccgtgaaaac cgggaaagaa gccgccgagg cgattcatca ctatttagag ggagcttgct
     5941 catgttaacg aaagatcttt cgattacttt ttgcggcgtg aagtttccca acccgttctg
     6001 cctctcttct tcgccggtag gcaactgcta tgagatgtgt gccaaagcct acgacactgg
     6061 ctggggcggc gtggtgttta aaacgatcgg cttttttatc gccaacgaag tctcgccgcg
     6121 ttttgatcat ctggtgaaag aagataccgg ttttatcggc ttcaaaaata tggagcagat
     6181 tgctgaacat ccgttggaag agaatctggc cgccctgcgt cggctgaaag aagattaccc
     6241 ggacaaagta ttgatcgctt caatcatggg cgaaaatgag cagcaatggg aagagctggc
     6301 gcgtctggtg caagaagctg gcgcggatat gatcgagtgt aacttctcct gtccgcaaat
     6361 gacttctcat gcgatgggta gcgatgtcgg gcaaagcccg gagctggtag aaaaatattg
     6421 tcgggcagta aaacgtggtt ccacgctgcc aatgctggcg aagatgacgc cgaatatcgg
     6481 tgatatgtgc gaagtggcgc tggcggcgaa gcgcggcggc gcagatggca ttgcggcgat
     6541 taacaccgtt aaatccatca ccaatatcga tcttaatcag aaaatcggta tgccgatcgt
     6601 taacggtaaa tcgagtattt ccggatattc cggtaaagcg gtaaaaccga tcgccctgcg
     6661 cttcattcag caaatgcgta cccatccaga gctgcgcgat ttcccgatca gcggtatcgg
     6721 cggtattgaa acctgggaag atgcggcgga gtttttattg ctcggtgcag cgacgttgca
     6781 ggtgaccacc ggcattatgc agtacgggta tcggatagtg gaagatatgg cgagcgggtt
     6841 gtcgcattat ctcgccgatc agggatttga ttcgttgcag gagatggtag gtctggcgaa
     6901 taacaatatt gtcccggcgg aagatttaga ccgcagttat attgtctatc cccatatcaa
     6961 tctcgataaa tgtgttggct gtggacgctg ttatatttcc tgttacgacg gcggtcacca
     7021 ggcgatggaa tggagcgaga aaacccgtac accgcattgt aataccgaga aatgtgtggg
     7081 ttgcctgctt tgtggtcacg tctgcccggt gggttgtatt gatctcggag aagtgaagtt
     7141 taagaaaggc gagaaagaac acccggtaac gttgtagaac ccgcgtcaca tccggcattt
     7201 ggcaccgaat gccggatgca gcgcatccgg caatacccac attcacatca tttcttacgc
     7261 gcgtatttca gtgaatccag cgctacggcg aagataataa tcgccccttt gatgatgtac
     7321 tgccagtatg ggtttacgcc gatatacgtc aggccatagt tgatgacggt aaaaataatt
     7381 accccggtca ccacgccaat caccgtcccc acaccgccgc tgaacgatac gccgcctacc
     7441 acgcacgccg cgatagcatc cagctcatac ataaagccga ggttattggt ggctgagccg
     7501 atacgtccgg cttctaacat cccgccgaag gcatagaaca caccagacaa cgcgtagatc
     7561 atcagcaggt tcaggccgac gttgacacca gatactttcg ccgcttccgg gttaccgcca
     7621 atggcaaaaa tgttcttacc gaagcgggtt ttgttccaca acacccagac gaacgccacc
     7681 gcaatcaacg cgtagaaggt gatgtaagag agacggaaac tccccagcgc gacaaagccc
     7741 tgagcaaagg tagagaagcc actgtcgaaa ccagaaatcg gcgacgcccc gacaaagtcg
     7801 taatagagcg agttgatgcc atagacgatg atcatcgtgc cgagcgtggt aatgaacggc
     7861 gtcacgttga gataagcgat aatcaggccg ttgatcaaac cgatcaccgc accaatggca
     7921 cagacaatca gaataaccag cgcaatcggc atcgtcgcca tttccgggaa cactttgttg
     7981 gcgttatcca tggactgcaa taacgtcgcc gctactactg ccgccagccc cacctggcgg
     8041 cctgcagaaa ggtcggtccc ctgggtgaca attaaccctg ccacaccaag cgcgataata
     8101 atacgcaccg atgactgggt gagaatatta cttaagttca acagacttaa aaatgttggg
     8161 tcctggaaaa taataatcgc cagcaaaact aaaagaacga cgtaaatacc gccttctttc
     8221 aggtaagtaa gaaaactttt cttatttaac gcactcatgg gaagccccta atcttaaagg
     8281 tgcaaagacg caagacgcag aatttcgctt tgcgttgttg tttttgtatc gacaattccg
     8341 gaaacgagac cattgctcat gaccagaata cggtctgtta tccctaacaa ctctggcatt
     8401 tcggaggaga taataataat ccccttgcct ttcttcgcca gttcggcaat taactgataa
     8461 atctcaaact tagccccaac atcaataccg cgcgtcggtt catcgagcat taatatttct
     8521 ggttgcgtta acagccagcg accaataatc actttttgct gattaccacc ggagagcgaa
     8581 cctatttgcg tccgatgacc tggcgttttt acccgcatcg aatcaatgac ccactgggta
     8641 tcacttttca tccgcgaatt atccagcaag ccaactttat ttttgtagtt gcgaatattg
     8701 gaaattaacg agttaaaacc gatatccaga taggcataaa ttcccgttga gcggcgctcc
     8761 tcagttacca gagcaaatcc gtggtttatg gcttcattgg cattatggtt attgatcttt
     8821 ttgccgtgca acgtaatggt gccagccgat ttctcgcgaa taccaaataa cgtctcaaca
     8881 atatcggtac gtttcgcccc caccagcccg gcaataccga ggatctcccc tttatgcaga
     8941 tcaaacgaga catcacggat cgacggctgg cgcagtgacg tcaggttacg cacctcgagg
     9001 atgacttcgc ccggcttgtt ttctttgtca gggaaacgct ggttaagaga acgcccaacc
     9061 atcatggcga tgatcttgtc catcgtcagc cctgccagcg gttcggtagc gatccactga
     9121 ccgtcgcgca atacggtaac ttcatcacat aactggaaga tttcttccat tttatgcgag
     9181 atataaacaa taccgcagcc gcgctctttt aatttacgaa taatagtgaa cagatgattg
     9241 acctcttttt cggttaacga agaagtcggt tcatccataa tcacaatttt cgcgttatag
     9301 gaaaacgctt tggcaatttc gatcatctgc atttgcgaaa cggataatgt gccgacgcgt
     9361 gcacgcggat cgatatcaat atccagttca tcaaaaatcg ctttggtttc gcggtacatt
     9421 ttgtcttgat cgacaaacat gcctttggtg ggatatcgcc ccagccacat gttatccatc
     9481 accgaacgtt gtaataccag atttaactcc tggtgtacca tcgaaatacc attttccagc
     9541 gcttctttgg cagaatggaa atcgatctct ttaccctgga ataaaatggt gccggagtct
     9601 ttttgataaa taccaaacag gcattttaat aatgtcgatt ttcctgcacc attttccccc
     9661 attaatgcat ggatagaatg tggtcggact tttaaattaa cgttatcaag tgccttaaca
     9721 ccaggaaaag acttgttgat accgctcatt tccaacaagt attccccgga agacggagtc
     9781 gttgagctga ccatataatt ttaccttgtt ggccatacaa taagggcgca gtaaacaact
     9841 gcgcccaatc agtcttattt cttgctgaat tcagccaggt tgtctttatc tacgccaaca
     9901 taaggtacgc ggaccacttt gttgtcgatt ttccagttgg tgccatcagc cgcacctttg
     9961 ccatcggcca ggtttttcgc caaatcaaag gtcgctttcg cctggttgtt agcatcgttc
    10021 agtacggtgc ccgccagtgc accggatttc accagcgcca gcgcttctgg cagcgcatcg
    10081 acgccaaaca ccggaatgct ggacttgttg tgtgctttca gtgcttctac cgcgcccatt
    10141 gccatcgcat cgttgttggc gataaccact tcgattttgt tggcgttcgg gccagatagc
    10201 caggcgtcca tcttatcttt cgcctgagcg gtatcccaca tagcggtatc taactgtaac
    10261 tgttcagttt tgatgccttt gtcgttcaat tctttaatca cgtaagtggt acgtgcttct
    10321 gcatccggat ggcccggctc acctttcagc agtacgaact gaatctgacc gtctttgttc
    10381 agatcccaac cctgattcgc cgcccagtgt ttagcaatca aatcgccctg aataatgccg
    10441 gactctttgg agtcagtgcc aacgtagtag gctttgtcgt agctatccag cgccttacga
    10501 gacggttctt tgttgaagaa aaccaccggc acgttttgcc cacgcgcttt ctcaatcacc
    10561 gtacccgcag ctgccgggtc aaccaggttg attgccagtg ccttcacccc tttcgccagc
    10621 aatacgtcga tctgatcgtt ctgcttggac tggtcattct gagaatcatt catcagcagc
    10681 tgaacatctg gcgcggcttt cgcatcttgc tcaatagcct tgcgcactac agacataaag
    10741 ttatcgtcgt acttatagat tgttacacca atgcgagtat cagcagcgtg tgcagcggca
    10801 ccgaataaca tgctggccat cacagcagac agggttaaca ccttcttatt catggtatct
    10861 ccggtttttc ttatgcaggg tagtgcttga gataaatgct cggcggggca gtagagttaa
    10921 tgaagtgtta ctgaacgccg aagctcactt tttaaaattc gttcttccat gcccggtaac
    10981 gctccagaaa acggctttaa ttgttgttat gacgctatta cctcggtgaa agtgattatt
    11041 cactgttaca tacgggttac aacgttaaaa cggtgcaatc atagctatca cattgttaag
    11101 atactgtgaa atcactcaca gattgaaagc ggttacatcg cctgatttgt tgagttagtg
    11161 atcgccgccg cattctggcg cgttgcgaca gaatgacgac gcactaacgt tggcataaaa
    11221 cagtggctgg cacgaggatc aatattgcct gctgccccct gcaaggccag ttcggtggct
    11281 aatttagcca ttgaagcaat gggataacgc acggtcgtta attgcgggtc ggtgtaacgg
    11341 gcgatgggaa tatcatcgaa accgatgatt gagagatgta acggaatcgc aatgccatta
    11401 tcttttaatg ctgtcagtgc gccagcagcc atattgtcgt tataagcaaa tacagcggta
    11461 agttgtagat tgcgccccag cagttcaacc atcgccgcct caccgcccgg catgtccggc
    11521 gtgccagtgc caatccagct ttccggcgga ataatattct gctctttcaa cgcactcatc
    11581 cagcctgctt tacgcatggc gtcatcttca atgccgtggc tggaagaaag ataaccaata
    11641 cgttgatgac cgttattcag caacatgcgc gtcgccattc gggcaccgct gagattatcc
    11701 aggcaaacgc aacgatgggc gtaccccggc acaacgcggt tgattaacac cataccggga
    11761 atgttatcca taaattgtgc cagttcatcg tcactcaatg cttttgagtg aacaatcaac
    11821 gcattacaac gctggcgaat taacacctca atggcgtgac gctctttttc cgcttcatga
    11881 tagctattgc cgattagcac gtatttctga tgctgctggg cgaccagatc caccgctttt
    11941 accagcgcgc cgaaaaacgc atcagaaacg tccatcacca ccacgccaat ggtgtcgcta
    12001 acctgagttg ccagcgcctg ggcattggca tttggtcgat aatccagctc actcacggct
    12061 ttcattactg cttcacgcgt gtcggcactg accagcgtgc tgttattgag cactcgggaa
    12121 accgttgcca cagagacgcc agcctgacgc gctacatcac gaatggtgat catattcact
    12181 acctgttatg agattgcagt aaatgactgc ttgctggcgg ctattttgtc agcactgaat
    12241 acaggacttc gtgaatcgag tcacagcaat ggaaacggtt acagccgttt tgttagcgaa
    12301 tgtgatccag atcgttatct tgatgtttta gatattgccg gtccggcagc acgcaaagtt
    12361 aactgacgcc agagccattc caccggcccc tggcggaagt aacgcagcca gataacagag
    12421 aagaagatat tcgccagcca taccggaata acaaacgcca gcagctccag acggtcaaac
    12481 tgcataaaca aactgaggtg gtaaaaaagc gtggtacaaa tcagcgtttg caatagatag
    12541 ttggtcagtg ccatccgtcc gacacaggcg attgccagca ccagcttaaa gcggcttaat
    12601 tgcggccaga agccataaaa cagcgacgca tagccaatcg cctgaaacgg cgcactcagt
    12661 tcccgcggca tttgaagtaa gaatgcacac cagcgatacg cccagtccag ctgccattgc
    12721 agggcgatgg caggaaggtt aatggtcacc ccaatcgcca ccagcacaaa accagtacga
    12781 cgatagtgac gtaagctgaa ctgccctttc agccagccgc tgcgcatcaa tgcggcacca
    12841 atgagcatca tccctgccag ttgccagcca tactgtgcgc ccagtgccag taaactgttc
    12901 ccaacaccat cggcacgatt actgatcgct tcaacgccgc cgtgaagctt ccagtatttt
    12961 tcatacaaaa tagccgatgc atccggcgtc caggcgcggc tggtctggct gtcggaaatc
    13021 agccccaata acagcaaaac gccaagcccc accagataaa gcatgacgcc tgtattaaac
    13081 aggcttttta ccgatggcgc atcgcgcacc agccgccagc agattaagcc caccagcccg
    13141 taagccagca gaatatcgcc gtcccagaac aataaaccgt gaataaagcc cagcaagact
    13201 aacagcgtta accgcgactg gatccagcgt ctgccacggg gcagcaacat ttgcaggcca
    13261 gcaccaaaca gcagcgcaaa aagcgtgagg aatttcacct ggccgatgag atcgagaaat
    13321 gcccaggtcc atgcatcctg cggcgtaata gcgccgtacc aggcgggatt gagataagcc
    13381 gcctttggta gcccaaaggc gctgatgttt aatagcagga tccccagaat ggcgacgccg
    13441 cgaacaaaat cgagcgtgac gttgcgctcc atggttcctg ccttttaatc agttgtgatg
    13501 acgcacagcg cgcagaaatt cgtggcgcgt attctgactg gatttgaaca atccaccaag
    13561 agaagtcgtt gttgtggcac tggttgcgtc gcggatgcca cgcgctttca cgcagtaatg
    13621 caccgcgtcg atagagacag ccacgttatt ggtgcccagc agcgtttgta gcgcaatgag
    13681 aatttgctgg gtcagacgtt cctgcacctg cggacgctgg gcaaagaact gcacgatgcg
    13741 gttaattttt gacagaccga tcaccgaatc tttcgggata taagccaccg tcgctttgcc
    13801 atcgatggta acaaaatggt gttcacaggt gctggtcagg gtgatatcgc gcacggtgac
    13861 catttcatcg accttcattt tgttttcaat gagggtgatt ttcgggaagt tggcgtaatc
    13921 cagaccggag aaaatttcat cgacatacat tttagcgatg cgatgcggcg tttccatcaa
    13981 actgtcatca gccaggtcga gattcagcag ctgcatgatt tcggtcatat gaccagcaat
    14041 aaggcttttg cgcgtttcgt tatccatttc atgcacgggc gggcgcagcg gtgtttccag
    14101 tcctcgcgca actaacgctt catgaaccag ggccgcttct ttactgagtg atggcattta
    14161 tgatttctcc tgcaggtgtg acgcctccgc cctgcgtggg ggcaaagtta ttaagctgat
    14221 ttacagcctg attattgtgc gtgaggcggc gcacataatc cagtattcac agcgataatt
    14281 attgtaattg ccgctgcctt tcatcagcag atgttaaaac atcgttatgc aaatacggaa
    14341 gtgaaagtta ctcacagcac attgaataaa cggtatgatg aagaaattgc aaacaacaca
    14401 acaaggagcc acgcatggaa atgctcgaag agcaccgctg ttttgaaggc tggcagcaac
    14461 gctggcgaca cgactccagt accttaaact gcccgatgac gttcagtatc tttctcccac
    14521 cacctcgtga tcacaccccg ccaccagtgc tgtactggct ttccggatta acctgcaatg
    14581 acgagaactt caccaccaag gcgggtgccc agcgcgtggc ggcggaactg gggattgtac
    14641 tggtgatgcc agacaccagc ccgcgcggcg aacaggttgc caacgacgat ggctacgatt
    14701 taggccaggg cgcggggttt tatcttaacg ccacgcaacc accgtgggcg acgcattacc
    14761 ggatgtatga ttatctgcgc gatgaattac cggcactgat tcagtcgcaa tttaatgtca
    14821 gcgaccgcag cgctattagc ggtcattcaa tgggtggtca cggtgcgctg attatggcgc
    14881 tgaaaaatcc gggcaaatac accagcgttt ccgcctttgc gccaattgtg aatccgtgca
    14941 gcgtcccgtg gggaatcaaa gcgtttagca cttatttagg tgaggacaaa aatgcatggc
    15001 tggaatggga cagttgcgcg ctgatgtatg cgagtaatgc gcagaatgcg atcccgacac
    15061 tgattgatca gggcgataat gatcagtttc ttgccgacca gctacaaccc gcagtgctgg
    15121 cagaagccgc gcgtcaaaaa gcgtggccga tgacgctgcg tattcagccg ggatatgatc
    15181 acagttacta ctttattgcc tcttttatag aggatcattt gcgcttccat gcgcaacatt
    15241 tactgaagta aagtctgccc ggttcgccgg gcatcttcct gtcagaagcg ataatccact
    15301 gccataaagt aacgacgtcc gtcttcgtta tagctgtagt cgtcacgact gagatccttg
    15361 tcgccaaggt tcagcacgcc tgcgcgcagt ttgacgtctt tagttacctg ccaggccgca
    15421 ccggtattcc agatggtata accgcccggt gttttagccg tcgcgctgtc ggcgcgtttc
    15481 tgcccggtat agtgaccaga aacatagaat gaccagtctt ccagcgccag cggtttccag
    15541 tccagcgtac cgttagcagt atggaacggc agatcggata gcggtttatt ttcgccgttg
    15601 ctgacatcac gaccatcgtt gtaggtgtag ttgagtgaca gtttccattc atcgttgaac
    15661 ggaattttca gttcggtttc cacgccctga atacgtgctt tgttaacgtt gtagtagcta
    15721 aataccggta tgcgccgtcc gttagcgccc gtctcaaaac caacaaagtt ttggtagccc
    15781 ggtgcagcgt tgacgtcaga cgtacggctg atgctgatac gatctttcac atcgttacgg
    15841 aaaacggtaa cgctggattc aaccccttcc agccagcctt cttcacccat gtagtaaagc
    15901 cccagctccc aactttcgct ggtttctggt ttcagatccg ggctacccac aatcttacat
    15961 gcgccacggc aggaattgct cgtccagtca gggctaagtt gcaacagaga aggtgcttta
    16021 aatgccgtcg cccagccccc tttcaccgtt acggtgtcgg tggcgttata aaccaggtag
    16081 gcacgcggac tccagtgttc accgtaggtt tcgtgatcgt ccatacgcac gccggtcgtc
    16141 agcgccagcg gctcgaagat ccgccattca tcttccacaa acagcgcgta ctggctggca
    16201 gacgttttgg agctggttcc cccggtcagg ttcaccgcat cgctaagttt gtcgtgacgc
    16261 cattcaccgc caaccgtgag aaactgatta atcgccgtca gcggcaacgt gtatttgccg
    16321 tcgaccgtat tgctttcgga agttatcggg ctgctgtagc cagggttttt gttctcgact
    16381 ttctcaccgt agtatttcag ttcgctggtg ccgtaatccc aacgcccatt atggctgacg
    16441 gagtagttct ggcgttccag gcggtttttg tccagcgagt cggaatcacg atcctgacgg
    16501 tcgaaaccgt atccggcagt aaaatcgtga ttttgattcg gtgtccaggc aaattcgaca
    16561 ttgccgtcgc ggctggagaa tccttcaata cgcggcgttt ctccggtatc ggtggtcgtt
    16621 gagttttgcg ggtcatcctt ttcacgtttt gccaggctgc cgtaagcttt cattcccagc
    16681 acgccgtcaa ttaatggtcc gctggtaaag aactgaccgt tataggtatc accgcgatcg
    16741 cgatgttcct gaacggtggt atcgacggta acggtgcccg accatttctg accgattttt
    16801 ttggtgatga tattcactac accgccgagc gcatcggaac cgtacagcga cgacatcggg
    16861 ccacggacca cttcaatacg ttcgatggaa tcgaccggga tccagttcag atcgaaatca
    16921 ttgtggcgga agacggcatt gcgggagtta acgcgtttac cgtcgacaag aatcagggtg
    16981 tagctgctgt ccagaccacg aatacttacg cccttacggt tatccccttc gttcgtcagt
    17041 tgtacgccag gcacttcttt gaggacatcc ttcagattct gtaccggttt tcgctgcagg
    17101 tcttcctggg taatgacgct gatactggcg ggtgcatctt taaggttttg ctcaacggaa
    17161 gatgcagtga caaccatcgt ttcgccatca tcatcgaccg ctaacacagg ccatgcacaa
    17221 gaaatagcgg acaaacacag cccgacccgt acgaaagggt tcaacctaaa cattccatat
    17281 ctccatgagg taactacgaa aataaaatgg gtatcgctca catcttcttt acgtcccctt
    17341 gcgtacggca gcatcgcggt ggacttattt gtatgcaggt gatcatccca gaaagccgga
    17401 acagcctctg atttgtcagc cttttttgat tgcggcgtaa cgataatgca aacgataaca
    17461 attatcaatc caaatgttaa attttatatc cgcatgattt gtcagggaaa tggaattgaa
    17521 aaagccctct cggttgagag ggcttagcaa ggaagggagg aaacttattt cttatcgttc
    17581 tgcgggaact tcatttcgct gtagcgtacg aagtgagttc ctttaatcag cttgtatccg
    17641 aaccaaataa tcaggaacag cgggatacca atatacgttg ccgctacgcc gccccagtca
    17701 atggtatctt tcaggaacgc ttcgtagttc tggcccaaag tgataatcag acacagaatg
    17761 aatgcgaaga tcggccccag tgggaagaaa cctgaacggt acggcagatc gttaatgtcg
    17821 tgtccctgca atacgtaccc gcgacggaaa cgatagtggc taatggcaat ccccagccag
    17881 gcgataaaac cggtcatccc ggaggtgttc agcagccaca ggtataccgt ctggttgcca
    17941 aacatggagg tcaggaagca cagacctgca atcaccgtcg tcgcatacag cgcattacgc
    18001 ggcacgccac cacgcgacag tttagcgaaa atgcgcggcg ctttaccgtc acacgccagg
    18061 gtgtacagca tacgagtaga cgcatacata ccggagttac ccgctgacag caccgccgtc
    18121 agaataactg cgttcatcac cgccgccgca gagagcagac ccgcgtgctg gaacaccagg
    18181 gtgaacggac tgacgctgat gtctttaaca tcgttacgca gcaggctcgg atcggtatac
    18241 ggaataatca ggctgataat caggatcgcg aacacataga acaacaggat tcgccagaat
    18301 acctgacgta ccgcgcgtgg aatgtttttc gccggatctt cggactcgcc tgcagcaata
    18361 ccgatcagct cggttccctg gaaagagaag ccgacaatca tagctacgcc gatcatcgcc
    18421 gcaaaaccac cagcaaacgg cgcttcgccg attgtccagt tgctccagcc cgcaggctgc
    18481 gcgcctttga agataccgat aatcatcagc acgccaacga tgataaagac aataactgtc
    18541 gtgactttga tcagtgagaa ccagtattcc gcttcaccaa agccacgaac tgagatgtag
    18601 ttcagcagga agataacgcc gaggaacagc gcactccaga tccagcccgg tgtatccggg
    18661 aaccaccagc tcatgaccag ctgagctgca accaagtcaa cggcgatagt caccgcccag
    18721 ttgtaccagt agttccagcc cagcgcgaag ccaaagcctt cttcaacata gttctgaccg
    18781 taagtggcaa acgaaccgga aaccggcata tatgcagcca gttcaccgag actggtcatc
    18841 aggaagtaaa ccatcaggcc aatcagcata tacgagagca atgccccgcc cggacctgcc
    18901 tgagaaatcg ttgcgccaga ggcaacaaaa agacctgtac cgatggaacc gccaatggca
    18961 atcatcgtca ggtgacgcgc ctttaattca cggcgtaagc ccggcgcttc tgtagtttta
    19021 gtttcggaac ccatacaaaa atgctatcca tcttaaaaat gaggcgcgat tgtagcagac
    19081 gattggcaat ccttccggca gaaatacacg gttataagac accttcatga tcgcccaggg
    19141 attataagta aagcagccaa tctcttttct ggcgaatgca tgctgagggc gctgcgtcac
    19201 gaaatcgaca cagcaccagc atgttcttgt acagcacctt aacgcggtac attcgcggga
    19261 tcgcaatagt ccaggaagcg ccgtagcgcg ttggaaaggt gtttttgccg atgatgtata
    19321 cgccacaacg tacgcatcag gcgcggaaga gggaccgcaa cttcacttaa tgtgcctgcc
    19381 tgcaattgat cttcaatcac ccgtcgcgac aggcaactaa tacccaaccc atgacgcacc
    19441 gcatgtttga ttgcctcgga gttacctaat tccatcgcca tctcaaactt cggtaaatgt
    19501 gacagcaaca gataatcgac aatctcccgc gtgccggagc cgcgttcacg caggatccac
    19561 ggcgcagcgg ccagctgttc taaggtgacc ggaccacgag ccaacggcga agtcggcgcg
    19621 gcgaaaacca ccagctcgtc ttccagccac ggttcagaga tgatttcagt gctgtggcac
    19681 ggtccttcaa taaagccaat atcaacgcgg aaatccagca ccgcttgcat cacgtcctgg
    19741 ctattcccaa cgctaagttc aatcggcaac tgcggataat catggcgata acgggcgata
    19801 actgcaggca gaatgtagtt accgatggta ctactggcat agatacgaat cgcgccgttg
    19861 tcttcgcgaa acagttgttc gatttcaacc gcctgttcaa gcagtgccaa cgctcgcgga
    19921 tagagcagcc gcccgtgttc attaactacc agtcttttcc ccacgcgatc aaacagttga
    19981 acgccaagct gcccttccag gtcggtcaag gctgcgctca ctgctgattg cgacaacgcc
    20041 agcatcaccg acgcctgggt ggttgatcca cttttcaata cttctgcaaa aacttccaac
    20101 tgccggaggg tgatgtgcat agtcgcttac cacttataaa gattaattat aaatatataa
    20161 tcaattttat ttttaaacca gttagtcgta accttatgcc cggttaaagg agagggttat
    20221 gacgaatatc accttacaga aacaacatcg tacactgtgg cattttattc cggggttagc
    20281 cctgagtgca gttatcaccg gggtcgccct gtggggtggt tccattcccg cggttgcggg
    20341 tgccgggttt agtgccctca ccctcgcaat cttgttgggg atggttttag gcaacaccat
    20401 ctatccgcac atctggaaaa gctgtgacgg tggcgtgctg tttgccaagc aatatttatt
    20461 acgtctgggt atcattcttt atggcttccg tctgacgttc tcgcaaattg ccgatgtcgg
    20521 tatcagtggg atcatcattg acgtgttgac gctgtccagt accttcctgc tggcttgctt
    20581 cctggggcag aaagtgtttg gtctggataa gcacaccagc tggttgatcg gtgccggtag
    20641 cagtatctgt ggtgctgccg cggtactggc gactgagccg gtagtgaaag cggaagccag
    20701 taaagtaacc gtggctgttg caaccgttgt tatcttcggg accgtcgcga ttttcctcta
    20761 cccggcgata tatccgctga tgtctcaatg gtttagtccg gaaactttcg gtatctacat
    20821 tggttctact gtgcacgaag tggcgcaggt ggtggcggca ggtcatgcca tcagcccgga
    20881 tgcagaaaac gcagcagtta tttccaaaat gctgcgcgtg atgatgctgg ctccgttcct
    20941 catcctgctg gcggcgcgtg ttaaacagct gtctggggcg aacagcggcg agaaaagcaa
    21001 aatcactatt ccgtggtttg ccatcttgtt catcgtagtt gccatcttta actcgttcca
    21061 cctgttaccg cagagcgtag tgaatatgct ggtaacgctg gataccttcc tgctggcaat
    21121 ggcgatggcg gcgctgggtc tgaccactca cgtcagcgcg ctgaaaaaag ccggggcgaa
    21181 acctctgctg atggctctgg tactgtttgc ctggctgatt gttggtggtg gtgcgattaa
    21241 ctatgtgatt caaagcgtca tcgcataaac cactacatct tgctcctgtt aacccgctat
    21301 cattaccgtt ttcctccagc gggtttaaca ggagtcctcg catgaaatac attggagcgc
    21361 acgttagtgc tgctggcggt ctggcaaatg ccgcaattcg cgccgccgaa atcgacgcaa
    21421 ccgcgtttgc cttgttcacc aaaaaccaac gtcagtggcg tgccgcaccg ctcacgacgc
    21481 aaaccatcga tgaattcaaa gccgcctgtg aaaaatatca ctacacatcg gcgcaaattc
    21541 ttccccacga cagttatctg attaacctcg gacatccggt cactgaagct ctggaaaaat
    21601 cgcgcgatgc ctttatagat gaaatgcagc gttgcgaaca gctggggctt tctttgctca
    21661 acttccaccc tggcagccat ctgatgcaga tttcagaaga ggattgcctt gcgcgtattg
    21721 ccgaatccat caacattgcg ctggataaaa ctcatggtgt gacagcggtg attgaaaaca
    21781 ccgccggtca gggcagtaac ttagggttta aattcgaaca tctcgcggcg attatcgacg
    21841 gcgtggaaga taaatcccgc gtcggcgtct gcattgatac ctgccatgct ttcgctgccg
    21901 ggtatgattt gcgtacttct gccgaatgcg agaaaacgtt cgcggatttt gcccgtattg
    21961 tcggctttaa gtatctgcgc gggatgcacc ttaacgatgc gaaaagcacc tttggcagcc
    22021 gcgttgaccg ccatcatagc ctcggtgaag gcaatatcgg tcatgatgcg ttccgctgga
    22081 tcatgcagga cgaccgtttc gacggaattc cgctgatcct tgaaaccatc aacccggata
    22141 tctgggcaga agagatcgcc tggctgaaag cgcaacaaac tgaaaaagcg gtagcctgaa
    22201 gatgaataac cgggagaagg agatccttgc aatattaagg cgtaacccgc tgattcagca
    22261 gaacgaaatt gcggatatgc tgcaaatcag ccgttcgcgt gttgcagcgc atattatgga
    22321 tttaatgcgc aaaggacgga ttaaaggcaa aggttacatt ctcaccgagc aggaatactg
    22381 cgtagtggtg gggacaatca atatggatat tcgcgggatg gcggatatcc gttacccgca
    22441 agcggcttct catcccggta ccattcattg ctcggcaggc ggcgttggac gcaatatcgc
    22501 ccacaatctg gcgctgttag gccgcgacgt tcatttgctt tcagtgattg gcgatgactt
    22561 ttatggcgaa atgctcctgg aagaaacgcg ccgcgccggc gtgaatgtct ccggctgcgt
    22621 tcgtttacat ggtcaaagca catcgacgta tctggcaatt gccaatcgag acgatcaaac
    22681 cgtgctggcg attaacgata cccatctgct ggatcagttg acaccgcaac tactgaacgg
    22741 gtcgcgcgat ttacttcgtc atgcgggcgt ggtactggca gattgtaacc tgacagccga
    22801 ggcgctggaa tgggtcttta ccctcgctga tgaaatcccg gtgtttgtcg ataccgtttc
    22861 agaattcaaa gcgggcaaaa tcaaacactg gctggcgcat attcacaccc tgaaacccac
    22921 tttaccggag ctggaaattt tatggggaca ggcgatcacc agcgatgctg accgtaatgc
    22981 cgcagtgaat gcattacatc agcaaggtgt tcagcaactg tttgtttatt tgcccgatga
    23041 gtcagtttat tgcagcgaaa aggatggaga acaatttttg ctgaccgcac cagcgcatac
    23101 gacagtagac agttttggtg ctgacgatgg ttttatggcg ggtctggtat atagctttct
    23161 ggagggaaac aatttccgtg acagcgcccg ttttgcgatg gcctgcgcag caatttcacg
    23221 cgccagcggc agcttaaaca accctaccct gtctgccgat aacgcgcttt cattagtgcc
    23281 gatggtgtaa caatgttgcc ggattcgacg cttgaccgcg tcttatccgg ctcataactc
    23341 gcgcactacg ctaaaccaat aaagaacccg gcaatggtgg cactcatcag gttagaaagt
    23401 gtcgccgccg ccagcgcgcg taaaccaagc tgggcgattt ccggcgcacg gtgtggcgca
    23461 accgcagaaa acgcccccac caccaccccg atagaaccaa agttagcgaa accgcacaac
    23521 gcgaaggaaa taatcgccac ggttttagca tccagagtgc cagctgtttg cagataaggt
    23581 gagaaattga ggtaagcgac aaattcattt attgccagtt tctgtccaat caaactcccg
    23641 gcaagattcg catcactcca gtcaacaccc attacccacg ccagtggggc cagcaggtaa
    23701 cctaaaatgg actccagcga ggcatgttca aaaccaaacc agccgccaac gccgccgata
    23761 ataccgttaa tcaacgcaat tattgcaaca aatgccatca ccactgtcgc cacacctgcg
    23821 gcgattttca gcccggtcat tgcccctgtc gcagcggctt caataatgct ttttggcggt
    23881 gtttcggtga aagagaggtt attaaaggaa acctgcgaag attccgtggc cggacttaac
    23941 aggcgagcaa ataagatccc gccagggatc gccattaacg atgccgccag caaatattcc
    24001 acaggtacgc ccagtgcggc gtaaccaatc attgtcgaac cagcaatcga ggccatgcca
    24061 ctacaaatcg ctgtaaataa ttcattgcga ttcagccgat cgataaaggg tttgacgatt
    24121 gccggaattt cgttttgccc gaggaaaatg gtagtgaccg cgacgaatga ctcgatcttg
    24181 ctgatattta atgctttctg gaagataccg ccgagaatgc gaattaagat ccccatcaca
    24241 ccgatgtagt agagaatact caccagcgcg gtgacgaaga taattgccgg taatactctg
    24301 aaaccaaaga taaatcctgc accatcaaac agcgtgtcca ttttcggccc gaccagcgaa
    24361 ccgaagataa atgcgctacc cgcgtcgctg tacgccatca ctttatggac gccaaaagcg
    24421 actttttcag cgacccaacg ccctggcggt aaccaaagca taatgccgcc aatcacgacc
    24481 tgtaacacta acgccgcgcc aacggtacgc aggctgatcc tcttcttgtt tactgacagc
    24541 aaaaatgcaa ttgccagcaa taccaccatt cccagaacac ttctcatgac atccatagtt
    24601 attatctctt catgtcattt tgggcgacgg ctttctgccc atcagaaatc gccgggcctg
    24661 catcttgcga tactgtcccg gcttgttatc aacacttaat gggttttgat gtagccgcgc
    24721 acgcactctt cgactaatcc ccagaaccag tcagtatcaa tagtgatgcc gactttggta
    24781 ttggcgggct tgccaagaac gcccagctcg tcgcagacgg tacgcccata gcaagggcca
    24841 ctgttaacat ccacttcgac gtacatctcc tgggttttaa tgccatctgg gttaatcaga
    24901 taaccgatgc aggtggcgtc atgcaccggg ccgccagcca ggccgtagtt ttcgaactgg
    24961 gttttgagag tgaagttcat gatgtcgctg aacagctctc cggcagggcc gcctgccctt
    25021 tccattcgtg caatcacgtc cggggtgcaa acggtctggt tggtgagatc gaggcccatc
    25081 attactaatg gaacgccgga ggtgaacacc acacgtgccg cttccggatc agcaaagatg
    25141 ttgaactcgg cagatggcgt gaagttgcca gtaccgtaag cgccgcccat cagtacaatt
    25201 tcacggattt tcggcagaat tgcgggttgc atccgcattg ccaccgcgat gtttgaaagc
    25261 ggaccaaccg gcaccagagt gatatcgcca tcgcttgcca tcagggtatc gatgatatat
    25321 ttcaccgcat gggtgttttc tgcctgacga gtcagcggtt cgaataccgg accatccagc
    25381 ccggtttcac cgtgaatatt atcggcaacg atttgttgac gcataatggg ttgcgacatc
    25441 cccgcataaa ccggaacatt aatctccagt ttctggcaaa cattcaggcc attaattaat
    25501 gttttatcga gggtttgatt ccccgccaca atagtgatac ctaataaatc aatcgccgga
    25561 tgtttcgctg ccatcatcat tgcaatagca tcatcatgac ccggatcaca atccagaata
    25621 atttttcttt tttccattgt ttatttcctc tgtttccagt tgcgttattt tttctacagc
    25681 aaagaaaatt cgaccgggcc gatgattgaa tcttaacaac agcgtacgta tgctaaatat
    25741 gagaaatctc atagcggata aacatcgtga aagaaatcca caataatgat cttaagcagc
    25801 aattgatgag tgaatccgcg tttaaggatt gcttttcaac ggatgtttca gccgatacgc
    25861 ggctgtttca ttttttagcg cgtgactaca tagtgcagga agggcaacag ccgtcctggc
    25921 tgttttacct gacgcgaggc cgcgccaggc tttacgccac gctagctaat ggtcgcgtgt
    25981 cgctgatcga tttctttgcc gcgccctgtt ttattggtga gattgagtta atcgataaag
    26041 accatgaacc gcgtgcggta caggctattg aagagtgttg gtgccttgcg ctccctatga
    26101 aacattaccg tccgctgtta ttaaacgaca cgctattttt acgaaaactt tgcgtcacct
    26161 taagtcataa aaattatcgt aatattgttt ctttaactca gaatcaatca tttccgttag
    26221 tgaatcgcct ggcagcattt atattactct cgcaggaagg tgatctttat cacgaaaaac
    26281 atacccaggc ggcagagtat ttaggtgtta cttatcgtca cttgctatat gtgatcgctc
    26341 aactcattca cgacggttta ttaattaaaa gtaagaaagg gtatttaatt aaaaacagaa
    26401 agcagttgtc aggactggcg ctggagatgg acccggagaa taaattctcc gggatgatgc
    26461 agtaaaaatt aatctgcaat agcgcgattg ccggatgcaa cacttaataa gcgcgtacat
    26521 ccggcaatga aactcaagct aaaccaataa agaacccggc aatggtcgcg ctcatcaggt
    26581 tggaaagcgt tgctgctgcc agcgcccgta aaccaagctg agcgatttcc ggtgcgcgtt
    26641 ttggcgaaat agccgaaaat gccccaacga caacaccgat agaaccaaag ttagcaaaac
    26701 cacaaagcgc aaaggagata atcgcaatgg ttttcacttc cagcgtgccg cccgtttgca
    26761 ggtatgggga gaaactcagg taagcgacga attcgttaat cgccagtttc tgcccaatca
    26821 ggctacccgc aagattggca tcactccagt ccacacccat gatccacgcc agcggtgcca
    26881 gcacatagcc aaaaatactt tccagagagg cattggcgaa accaaaccag ccgccaattc
    26941 cgccgataat gccgttgatc agcgcaataa ttgcgacaaa cgccattact accgttgcta
    27001 caccagcggc gattttcagc ccggtcatcg caccgctcgc cgctgcttcg ataaagcttt
    27061 ttggcggcgt ttcgctgaac gataaatttt caaatgtgac ctgcgaaggc tcggttgccg
    27121 ggctaagaat acgtgcaaac aaaatcccgc cagggatcgc catcagcgat gccgctaaca
    27181 ggtagtcaat tggtacgccc attccggcat aaccaatcat catcgaaccc gcaatggacg
    27241 ccatcccgct acaaattgcg gtaaacaact cgttgcgatt catgcgatcg ataaacggtt
    27301 taacgatcgc agggatctca ttttgcccga ggaaaatagt ggtaaccgca acaaaagatt
    27361 cgattttgct gatgttgaga gctttctgaa aaatactgcc aagaatgcgg attagcagcc
    27421 ccatcacgcc aatgtagtac agcagactga tgagcgcagt aacgaaaata atcgccggaa
    27481 gtacgcgaaa ggcgaagata aaacccgcac cgtcaaacaa gacatccatt ttcggcccaa
    27541 ccagcgaacc aaaaatgaag gcgctaccgg catcactgta agacatcact ttatgaacgc
    27601 ctaatgccgc cagttctact gcccattttc ccggtgggaa gtagagcatg atgccaccaa
    27661 tagcaatttg cagcagcagc gcggctccaa ccgtgcgcaa actgatgctc tttttattca
    27721 ctgacaacag aaatgctatt gccagtaaca ccaccatccc cacaacactt ctcattatat
    27781 ccataatgat tttcccttca tgccagtaaa cccggcgtca gcgccaggtt ttggtatgta
    27841 tgatcagtac gggcgacggc tttctgcccg tcagaaatta acccgcgaga cgctggtatt
    27901 ctttggcaat ttcgctcgcc agaatggcgt tgttgaacac cagttggatg ttggatttca
    27961 ggctgtcacc gccagtcagt tcagcaacac gagccagtag gaacggtgta ctttctttac
    28021 caataacgcc ctgctcttcg gcttcggcga cggcttgatc tatggctgca ttgatagatt
    28081 cctccggcat cgcaaactgc tccgggatcg gattcgccac taccaggccg ccgttcaaac
    28141 cggtttgcca tttcactgcc attgcacgag cgatttccgt ggcactatca aggcgaatgc
    28201 tgacgtcaaa cgggctggta cggcagaaaa acgcaggcag cgcttttgtc tgatagccaa
    28261 ttaacggcac accgaaggtt tctaaatatt ctgttgttaa tcctaaatcg agaatagatt
    28321 ttgcaccggc acaaacaacg gtgacattag tatttgccag ttcttgcaaa tcggcagaaa
    28381 tatcgaaggt atgttccgcc ccgcgatgca caccaccaat tcccccggtg gcaaatactt
    28441 taattccggc aagcgccgca ataatcatcg ttgaagccac agtggttgcg ccattttttc
    28501 cggcggcaac gacaaaaggt aaatcgcgac gactaacttt ggtcacgtta tgcccttcgc
    28561 gacccagcaa ttcaatttct tctttgctta aacccacttt catcacgccg ccaataatgg
    28621 cgatagtggc aggtacagcg ccctgtttac gaatagtttc ttcaacttca attgcggtct
    28681 gggcattttg tgggaacggc atcccgtgag aaataatggt cgattccagc gccacaaccg
    28741 gttttttgtt ttttaaagcg tcctgcactt ccggggaaat ttgtaataat tcaggggaaa
    28801 tttttaattc agacattctg cgttctccac taacgatata acgttggcaa tcgataaatc
    28861 ggggttattg gtgtattcac aggagagcgc cattgacgaa catccctgtg cgaaacgaac
    28921 agattcggca aacggcattc cgtctaccca acacgaagca agtcccgcca tcatggcatc
    28981 gcccgctccg gtaacattaa taacattggt tttgatcggc gcagaccagc cactttcacc
    29041 gctgatatcg ctgtaataaa cgccatcgcc gcccatgctc aataccagtc ggttcagccc
    29101 atgttgatgg aaccaggcag caacttttgc cacatcttca cgccctgaca gcgcaatccc
    29161 actcagggtt tccgcttcaa ggcggtttgg cttgagagtg tggatttgat ttagacggtc
    29221 gcgcactttg acacatttcc acgcagaaac cggatcgaca aatacgggta cgttggcggc
    29281 attatccaga atccatgcca gtgcctcttc actgatatta cagtccgcga caatgacctt
    29341 tgccctctga ataaattcac gatgctgtgc gagatattca gctgtaatag cgttgctaat
    29401 attcatgtca tttatagcaa ctagcatttc accggtatta tcgagtaatg ataaatagct
    29461 cgacgtattt tctcccggca caatcaggca tttatcgaca taaacaccag attgattggt
    29521 ttgcgttagc aacgattgac cataaaaatc actgcctact gcgctcagta gccaggcttt
    29581 attccccagc aacgccaggt tttgtgcaat attgcgccct actccaccag gcgtaaactt
    29641 tattttacct ggatttgaat ccgcataatt taatgattca tgtgaatatc cggcgacatc
    29701 aatattcgcc gaacctataa ttacgacata atccttttcg cgcatagcac gtcctctggt
    29761 aaaaaattac caaccctgtc aatccacaag aatatagata ctgcaaagac ggtttaaaca
    29821 tgtgttcata tttaaacatg tgctcatagt atgcatgttt tacgtaaagt aaattaccgc
    29881 cagagaggca aaatgggcag atttgagcag gctcacaaaa cgcgattaaa tgcctgaatt
    29941 ataaaaacgg ggaatttgtg acgggaggca cagaacagga acaataaaaa agggcagaaa
    30001 ttaatctgcc cttgaggaaa taaccttagt gtttgatgaa agtttcaggt ttccactaaa
    30061 agataaaacc atttaaattc ataaaattac attcacaaac cggtcattct ctttgcgcgc
    30121 atcaaatgtt ccagggcagg aaatttctgc cctggaacac accttttatt acgctgcttt
    30181 tgctactgcg tccacttccg gacgtttcag gaaggcatag gccagacccg ccaccagcgt
    30241 accggcaata atggctacca ggtaacccaa taccggcgta atcgcgccag ggatcagcag
    30301 aacaaacaga ccaccgtgcg gtgccatcag tttcgcacca atcgccattg agattgcgcc
    30361 agtcagcgcc ccacccacga tacagcacgg cagcacacgc atcggatcac gggcagcaaa
    30421 cggaattgca ccttccgaaa taaagcacag tcccagtacc agagcagctt tgcccccttc
    30481 ctgctgcgcc ttgtcgaatt tgcgacgcgc taccattgtt gccagcccca ttgccagcgg
    30541 tggcaccata cctgccgcca taatcgccgc catcgggcca taggtttgag tactcagcag
    30601 acccacaccg aacgcgtacg ctgctttgtt taccggaccg cccatgtcag tacacatcat
    30661 gccaccgagg atcgccccca gcagaaccgc attcgcagtc cccatggtct gcagccagtg
    30721 agtcaaccct tcgagaatgc cagcaaccgg tttaccgatc aggtagatca tcgccagacc
    30781 gaccaccaga ctggaaatta gcggaatgat cagaatcggt ttcagcgcct ccatactctg
    30841 tggcagtttc aattgcgtac tgattaactt cgcaatgtaa ccagccagga agcccgcaat
    30901 aataccgcca atgaagccag aaccggtgct gaccgccagc ataccgccaa tcagacccgg
    30961 cgtgaggccc ggacgatcgg caatggaaaa ggcaatataa cctgccagta ccggcaccat
    31021 tagcgcaaag gctgaacctc caccaatctg catcagcgcc gcagccaacg tacccggctc
    31081 tttaaacgct tcgataccaa aagcaaaaga aagcgcgata cacagaccac ctgcaacgac
    31141 catcggcagc atgtaagaga cgcccgtcag caagtgacgg taagcgcctg cactctcttt
    31201 cttaccttca gtggtcgctg tttgagcttt gcccgctggt tcatacggcg ttgcttcagc
    31261 aaccgcttta tccagttcct gcgcagtttt cttcagcgcc agaccggtag aggtgcgata
    31321 catcggttta ccagcaaatt tcgccagatc cacttcgata tctgccgcca caatcaccag
    31381 atccgctgcg gcgacttctt caggggtgat tgcattacct gcgccaacag aaccacgggt
    31441 ttcaactttc acccaccagc cacgtttttt cgcttcggtt tcaatggctt cagccgccat
    31501 aaaggtgtgt gctacgccag tcgggcaagc agtcaccgca actacgcgtt tcggaccgct
    31561 ggcggcaacc ggtgctgtcg cagcgaccgg cgcagtgtaa ggtttcgcat ggcctttggc
    31621 ttcactcagg aacagctcag ggtgcgcaac tgcccgggaa atatcgccca gccagacatt
    31681 tttaccgttc agcgcgctgt cgttcgggat ggaatcaccg agaacaatcg ccatttcagc
    31741 gtcgttcgga ttgtcgatga tttccagttt tgcttttcgc gccgccgcgc ccagcagggt
    31801 cttcgccata taggcgcgtg cctgaccgag attagcgtca ataatcagca gcgttttcat
    31861 tatgcctctc ctgctgtcag ttaaaaggtt gtaagtcgac gcgcgccatc attgcggcca
    31921 actgcggacg atcggtaata cccacattgc tttgacttac cgccagggct gcaacagctg
    31981 tcgccagacg cagtgtgtgt tcactggatt cacgcatcag caagccataa atcaggccac
    32041 caaccataga atcccctgcg ccaacggtgc ttacgacatc gactgacggt ggtttggcga
    32101 tccattcgcc ggaggcatta acccaaagcg cgccttcggc acccagtgaa ataacgacat
    32161 gcgcgatacc ctgttcacgc agcgcatgcg cagcttcaat cacatctttc atttcaggca
    32221 gtttacggcc cgcccagatt tccagctcgc ggcggttagg tttcaccagc cacggtgccg
    32281 ctttcaaacc tgctactaac gcttcacggc tactatcaaa gataatgcaa ggacactgac
    32341 tacgcaggcg agtcatccag tcggtgaacg cttccgggct gacgcctgac ggtaagcttc
    32401 cgctgacaca gaccatatcg aactgaccga gccagctcag agaatcagtc acaaagcgtt
    32461 cccagtcggc gggggtgact tcaaaacccg agaagttgaa gtcggtcact tcgccgtctt
    32521 tttccgtcag cttaacgtta attcgggtgc gcccctgtac aacctggaaa cggttggcaa
    32581 tgcccagctc gctgaacagt tgctgaaaac catcctgatt gtctttaccg aggaagccgc
    32641 caacggtgac atcaattccc aggtctttta atactttggc cacgttgatg cctttacccg
    32701 ccgcatgcag accggtggtt ttcaccaggt tcacttcgcc gcgttcaatt tccgggcaga
    32761 aaccaacaag gtcataagcc ggattaaggg tgatagtagc aacacgtctg ctcattatgc
    32821 gccctcccca agaccagcag cgatagcgtc gccaatggct ttcagcgcct gttcagcatc
    32881 tgcaccctgg gcggtaaagc gtaggcgatg acctttctta acgccaagtg ccacaacttt
    32941 catcagacta cgtccgtttg ccggtttgcc ggtgccatca aggtttgtca cggtaatatc
    33001 actgttaaat tgtttaatgg tattgaccag catggtacct ggacgagcat gcaggccgtg
    33061 ttcattgcgc accacaaact ccgcgcttaa cacgtcgtcg gtcggcgcat catcgctggt
    33121 cagcagtgcc agcaacgttg ccgcatccgc tttcagcaag cggtcagctt tattatcgag
    33181 taacaaatca gcgagacgct taagaaccgc gacgggctga tcgtcattca tcgccacact
    33241 caccagcatg gctgccgttt cgccgtccac atcaaaagca tttgccgcac ggcttaccgc
    33301 aatcgcgcta cgcagattgc cttcggcgct atcgctcagc cagataccct gtccgaggtt
    33361 cagcggttgt tcattgatgg ctttggtgac gaaagtggcg tcaactgccc ccgcctcttt
    33421 cagacgcgca gcgttcagcg cctgaagagt cagcagatcg ctggcgacga tatccagcgt
    33481 cagcatttcg ttgtcgagct tcagctgctc actctgcttt tcgcccatca gcaatgcgcg
    33541 aagttcttct gctgttgttg ctgacttcag ctgttcagca acggaatcat cgctcagtac
    33601 gtgggtcagc tggcgtagca ggcccagatg ttcatccgag ctggcagcaa taccgatcgc
    33661 cacgtacgct acctggccgt caccccaggt gacgccttcc gggaactgaa atacctgaac
    33721 gccggttttc agcacctgat cgcgggtgtc ggtagtgccg tgtggaatag caataccatt
    33781 gccgaggaac gtagaggttt gctgttcgcg cgccagcatg ccattgacgt agccttcagc
    33841 tacattaccg gcctgcacca gcgccgcagc gacctggcga atcgcctctt ctttgtctcc
    33901 ggccttttcg cccggatgga tgtcctgtac ggataactgg aacatagttc tcctctcttg
    33961 ctgaattgaa acgattcagc ttctatgaga aaaaaagcgc caacctggct tagggttaaa
    34021 gacaagatcg cgctgaaacg tttcaagaaa gaataatact tctgtttcag cacgcaagga
    34081 aagccgtaaa gtaatgagca aaagtttgat gtgctgcaca attttttgtc atttttccta
    34141 attgctgatg ggaaaatccg ttatcagcaa tttcatttca gcagcgtcag cagccaatca
    34201 gcaacagtga aatggcattt tgattattcg tggcgctttt gatttcgctg tctgtttatt
    34261 ttctaacaag cagcgtaaac tccgcgtctt cctcttccag tgatcgacca gcatgcataa
    34321 ctcccccgca gtctccagcg cgaaatcgtt tgacctgacc tcgacggcgt ttttaatcgt
    34381 tgcctttctc accggtattg cgggcgctct gcaaaccccg acactcagta ttttccttac
    34441 cgatgaagta catgcccgtc cggcgatggt gggattcttc tttaccggca gcgctgtcat
    34501 tgggattctg gtcagtcagt ttctcgccgg gcgctctgat aagcgcggcg atcgcaaatc
    34561 gctgattgtc ttttgctgcc tgttaggcgt gctggcctgc accctttttg cctggaatcg
    34621 caactacttt gttttgctat tcgttggcgt ctttcttagc agctttggct cgaccgctaa
    34681 cccgcaaatg tttgcccttg cacgtgaaca tgccgacaaa accggacgtg aggcggtgat
    34741 gttcagctct tttttacgcg ctcaggtttc actggcatgg gtcattggcc cgccgctggc
    34801 ttatgcctta gcgatgggtt tcagctttac ggtaatgtat ctgagcgcag cggtagcgtt
    34861 tattgtttgc ggcgtgatgg tgtggctgtt tttaccgtcg atgcaaaaag agcttccgct
    34921 ggcgaccggc acggttgaag cgccgcgccg taaccgtcgc gatacgctgc tgctgtttgt
    34981 catttgtaca ttgatgtggg gctcgaacag cctgtacatc atcaacatgc cgctatttat
    35041 tatcaacgaa ctgcatcttc ccgagaaact ggcaggcgtg atgatgggga ccgccgccgg
    35101 gctggaaatc ccgaccatgt tgattgccgg atattttgcc aaacgtctgg gtaagcgttt
    35161 cttaatgcgc gttgctgccg tgggtggcgt ctgtttttac gcaggaatgc tgatggcgca
    35221 ttcacctgcc attctgttgg gcttgcagct gctaaatgct atttttattg gcattctggg
    35281 cggcatcggg atgctttatt ttcaggattt gatgcccggt caggcaggtt cagccaccac
    35341 gctctatacc aatacgtcgc gcgtgggctg gatcatcgca ggatcagtgg cgggcatcgt
    35401 cgccgagatc tggaattatc acgctgtgtt ctggtttgcg atggtgatga ttatcgccac
    35461 tctgttttgc ttactgcgga ttaaagatgt ttaaggcgcg gtcagcattt ccagatcgat
    35521 aagccaggtc attgcctgct gacgcgagtt accgcacatt tcagcgctgg cttgtaagcc
    35581 tgcacagact ttcggccgca gtggcgaggt gaaaatttta cagcgttgct gttcatcaag
    35641 ctgaatgcag ggcgtattgg cgggcttgcc atctggcata ccgggaatag ggctggaaat
    35701 tgaaggggca gtgcaacacg ccccgcaacc cggacggcat tccatacgtt gttctcttaa
    35761 ggttaaccac cggattgatg agcgcgcaca gtaccacctt ttttgcacca gcaaaagtgc
    35821 gaataccact tgcccgaaag gcccgtcgcg agtactttgt cgcgatattt ttgacatttt
    35881 cgactacagg aatttttcga tgccaagagc gaacgaaatt aaaaaaggta tggtactgaa
    35941 ttacaacggc aaactgctgc tggttaagga tattgatatt cagtcgccca ctgcccgcgg
    36001 tgccgctacg ctgtacaaaa tgcgtttttc tgatgtccgt accgggctga aagtagaaga
    36061 gcgtttcaaa ggtgatgata tcgttgacac cgtgacgctg acccgccgtt acgttgactt
    36121 ctcctatgtc gatggcaacg aatatgtctt tatggataaa gaagactata ccccgtatac
    36181 cttcaccaaa gatcagattg aagaagagtt gctgtttatg cctgagggcg gcatgccgga
    36241 catgcaggtg ctgacctggg acggtcaact gctggcgctt gagctgccgc agaccgttga
    36301 tctggaaatc gttgaaaccg cacctggcat caaaggggca tctgccagcg cccgtaacaa
    36361 accggcgaca ttgagcactg gtctggtgat tcaggtacca gaatacttaa gcccgggcga
    36421 aaaaattcgt atccatatcg aagaacgccg ttatatgggt cgtgctgact aacttcagcc
    36481 gcatgcagaa aagggatagc tcaggctgtc ccttttttaa tttattatac caatcttcta
    36541 ttttgcgctt cctgaacacc ttacgcccgc aattttcact cgttgattga tcgccctcac
    36601 acttcatcgc attaacaatc cagaccaatt tcaattgctg tcatataact ttacactgtc
    36661 attgttaatt aatcgttact aagacgtgac tcctatgaat acaatcgcct ccgttacgct
    36721 cccgcatcat gtacacgctc cacgctacga tcgccagcag ttgcaatcac gtatcgttca
    36781 ttttggcttt ggagcctttc accgcgctca tcaggcgtta ctgaccgatc gtgtgctgaa
    36841 tgcccagggc ggcgactggg ggatctgtga gatcagcttg ttcagcggcg atcaactgat
    36901 gagccagctc cgcgcacaga accatttata taccgtgctg gagaaaggtg cggacggcaa
    36961 tcaggcgata attgtcggtg ccgttcacga ctgcctgaat gcaaaactgg attccttagc
    37021 ggcaattatt gagaaatttt gcgagccaca ggtggcaatt gtttccctga cgattaccga
    37081 aaaaggctat tgtattgacc cggccaccgg tgcactcgac accagcaatc cgcggattat
    37141 tcacgatctt caaaatcctg aagaacctca ctccgcgccg ggtattctcg tcgaagcact
    37201 gaaacgacgc cgtgaacgcg gccttgcacc gtttaccgta ctctcctgcg acaatattcc
    37261 cgacaatggc catgtggtga aaaacgcggt gctggggatg gcggaaaaac gttcaccaga
    37321 actcgccggg tggataaaag aacacgtcag ttttccggga accatggtcg accgtattgt
    37381 tccggcagca accgacgaat cactggcgga aatcagccag catctggggg tgaatgatcc
    37441 ctgtgcgatt agctgcgaac cgtttatcca gtgggtggtg gaagataact tcgtcgctgg
    37501 gcgtcctgcc tgggaagtcg caggtgtaca aatggtgaat gatgtcctgc catgggaaga
    37561 gatgaaactg cggatgctta atggcagcca ctcttttctc gcttatctgg gttacctctc
    37621 aggattcgcc catatcagtg attgcatgca ggatcgcgca tttcgccatg ccgccagaac
    37681 attaatgctg gatgagcaag cgccgactct gcgaattaaa gatgtcgatt taacacaata
    37741 tgcggataag ttaattgcac gttttgctaa cccggcgctg aaacataaga cctggcaaat
    37801 cgcgatggat ggcagccaga aattaccgca acgtatgctg gcaggtattc gcatacatct
    37861 ggcgcgcgaa acggactggt cgttgctggc attaggcgtt gcaggctgga tgcgttacgt
    37921 cagcggcgtt gatgatgcag gaaatgccat tgatgttcgc gatccgctta gcgataaaat
    37981 ttgcgaactt gttgcgggca gtaacagtga acaacgcgta accgccctgc tttctctgcg
    38041 tgaagttttc ggtgatgatc tgccagataa cccgcatttt gtgcaggcaa tcgaacaagc
    38101 ctggcaacaa atcgcacaat tcggcgcgca tcaagcgcta ttaaacaccc tcaaaattta
    38161 acgatttctg cggttaaagc ggatgaagct cgccttcgtc cgctctcccc ttctcttttc
    38221 tgcctttttt agccaggatt aacgctcagt taacttttaa gagtattgcg gagccgttgt
    38281 gaccagaacc aacctcatca ccggttttct cggcagcggg aaaactacgt cgattcttca
    38341 tctgttagcc cataaagatc ccaacgaaaa atgggcggta ctggttaatg aatttgggga
    38401 agtcggaatt gatggtgctt tgctcgccga tagcggcgca ttgctgaaag agatccccgg
    38461 cggctgcatg tgctgcgtta atggtttacc tatgcaggta gggttgaata ccttactgcg
    38521 tcagggaaaa ccagaccgct tgttgataga gccgaccggg ctaggccatc cgaaacagat
    38581 cctcgatctc ttaaccgcac ccgtctatga accgtggata gatctgcgcg ccacgttgtg
    38641 cattctcgat ccacgcctgc tgctggacga aaaaagcgcc agcaatgaaa acttccgtga
    38701 ccagctggct gccgcagaca ttattgtcgc caataaatcc gaccgtgcga cgcccgaaag
    38761 tgagcaagcg ctacagcgct ggtggcagca aaatggtggc gatcggcaat taattcacag
    38821 tgagcatggg aaagttgacg gtcatcttct ggatttgccg cgtcgcaatt tagccgagtt
    38881 gcccgccagc gccgcgcatt ctcatcagca tgtcgtgaaa aaagggttag cagcgttaag
    38941 cctgccagag catcaacgct ggcgtcgcag tctgaacagc gggcaaggat atcaggcctg
    39001 cggctggata ttcgacgctg atacggtatt cgacaccatt ggcattctgg aatgggcgcg
    39061 acttgcaccg gtagaacgcg tcaaaggcgt gctgcgtatt cccgaagggc tggtgcgaat
    39121 caaccgtcag ggcgatgacc tgcacattga aacgcaaaac gttgcgccac cggacagccg
    39181 tattgagctg atttccagca gcgaagctga ctggaatgcc ttgcagagcg cgctgttgaa
    39241 gcttcgttta gcgactaccg cgtaaggttg cctgcgtttt tcagtaagat aattagagaa
    39301 aatatgatta aaaatttgcc gcaaatagtg ttgttgaata ttgtcggcct cgcgctgttt
    39361 ctttcctggt atattcccgt taatcatgga ttctggttgc cgattgatgc ggatattttt
    39421 tatttcttta atcagaaact ggtcgaaagt aaggcctttt tgtggctggt tgcattgacc
    39481 aacaatcgcg ccttcgacgg ttgttcactg ctggcgatgg gtatgttgat gctgagtttc
    39541 tggctgaaag aaaacgcccc tggcagacga cgtatcgtga ttattggtct ggtcatgcta
    39601 ttaactgcag tggtattaaa ccagctgggt caggcattaa ttcctgtaaa acgggccagc
    39661 ccaacattga cttttaccga tattaaccgc gtcagcgaac tgctctctgt tcccacgaaa
    39721 gatgcctcac gagatagctt tcccggcgat cacggtatga tgctgcttat tttttcggca
    39781 ttcatgtggc gttatttcgg caaagttgca ggccttatcg cccttattat ttttgtggtt
    39841 tttgcatttc ccagagtaat gattggcgca cactggttta ctgacatcat tgttggttcg
    39901 atgaccgtga tattgatcgg tttgccctgg gtgttgctga cgccattaag tgatcgatta
    39961 atcacctttt ttgacaaatc actaccggga aaaaacaaac atttccaaaa caaataactc
    40021 acagtaatta acatcatcag ggttattttt atagtgagga taatcctgat gatgcgcacc
    40081 gtgctttcat ctatcgaacg caaaaatcat tctctaagta aatgaatgta ttgcatgcgt
    40141 ttcactcaat cgtactttaa ttgaccaatc ccgcttatta actttctgta tcactttttc
    40201 ttataaaaaa tcatgtaaaa ccgctcgcca agaccgcacc aatcgggtaa tctcgaactc
    40261 gttttgcctc ggcggtagat tatcctcaca gcatataatt ttgtgcgtta gtccacagat
    40321 ttggccttaa ggaattgttt caacatgccc aggtaattag tctcgtgtcg cttggcattt
    40381 ttttataacg atatttgtcg ttaaggactt caagggaaaa caaacaacat ggtcaaatct
    40441 caaccgattt tgagatatat cttgcgcggg atccccgcga ttgcagtagc ggttctgctt
    40501 tctgcatgta gtgcaaataa caccgcaaag aatatgcatc ctgagacacg tgcagtgggt
    40561 agtgaaacat catcactgca agcttctcag gatgaatttg aaaacctggt tcgtaatgtc
    40621 gacgtaaaat cgcggattat ggatcagtat gctgactgga aaggcgtacg ctatcgtctg
    40681 ggcggcagca ctaaaaaagg tatcgattgt tctggtttcg tacagcgtac attccgtgag
    40741 caatttggct tagaacttcc gcgttcgact tatgaacagc aggaaatggg taaatctgtt
    40801 tcccgcagta atttgcgtac gggtgattta gttctgttcc gtgccggttc aacgggacgc
    40861 catgtcggta tttatatcgg caacaaccag tttgtccatg cttccaccag cagtggcgtt
    40921 attatttcca gcatgaatga accatactgg aagaagcgtt acaacgaagc acgccgggtt
    40981 ctcagccgca gctaataaac cgtttggatg caatcccttg gctatcctga cgagttaact
    41041 gaaagcactg cttaggcagt gcttttttgt tttcattcat cagagaaaat gatgtttccg
    41101 cgtcttgatc caggctatag tccggtcatt gttatctttt aaatgttgtc gtaatttcag
    41161 gaaattaacg gaatcatgtt tatacgcgct cccaattctg gacgtaagct cctgcttacc
    41221 tgcattgttg caggcgtgat gattgcgata ctggtgagct gccttcagtt tttagtggcc
    41281 tggcataagc acgaagtcaa atacgacaca ctgattaccg acgtacaaaa gtatctcgat
    41341 acctattttg ccgacctgaa atccactact gaccggctcc agccgctgac cttagatacc
    41401 tgccagcagg ctaaccccga actgaccgct cgcgcggcgt ttagcatgaa tgtccgtacg
    41461 tttgtgctgg tgaaagataa aaaaacattc tgttcatctg cgactggtga gatggacatt
    41521 ccactaaaag aattgattcc ggcgctcgac attaataaaa atgtcgatat ggcgatctta
    41581 cccggtacgc cgatggtgcc gaacaaaccc gcaatcgtca tctggtatcg caaccctttg
    41641 ctgaaaaata gcggcgtctt tgccgctctg aatctcaatc tgacgccttc actcttctat
    41701 agctcacggc aggaagatta cgatggtgtc gccctcatta ttggtaatac tgctctatct
    41761 accttttcgt cacgtttgat gaatgttaat gaattaaccg acatgccggt ccgtgaaact
    41821 aaaattgcgg gcattcctct gaccgttcgg ctttatgcgg atgactggac atggaacgat
    41881 gtgtggtacg catttttact gggtggcatg agtggaactt tcgttggact tctctgctat
    41941 tacctgatga gtgtgcgtat gcgcccaggc agagaaatca tgaccgccat caagcgcgaa
    42001 caattttacg tggtatatca accggtggtt gatacacaag ctttgcgggt aacgggcctg
    42061 gaagtactgc tacgctggcg gcatccagta gcaggagaaa tccccccgga tgccttcatt
    42121 aactttgccg aagcgcaaaa gatgattgtg ccactgactc agcacctgtt tgagttgatt
    42181 gcccgcgatg ccgcagaatt agaaaaagta ctgccggtag gcgtcaaatt tggcattaac
    42241 attgcgccgg cccacttgca cagcgaaagc tttaaagcgg atatccagaa actactcact
    42301 tccctgcccg cacaccattt ccagattgtg ctggaaatta ccgagcgcga tatgctgaaa
    42361 gagcgagaag ccacacaact cttcgcctgg ctgcattcgg tcggcgtaga aattgctatt
    42421 gatgacttcg gcaccgggca cagcgcgctt atctatcttg agcgttttac gctcgattat
    42481 ctgaaaattg atcgtggatt tatcaacgcc atcggtacgg aaacaatcac ttcacccgta
    42541 cttgacgcgg tgctgacgct ggcgaaacgt ctcaatatgc tgacagttgc tgaaggggtc
    42601 gaaacgccag aacaggcacg atggctaagc gaacgcggcg ttaatttcat gcaaggctac
    42661 tggattagtc gcccgttacc gctggacgat tttgttcgct ggctgaagaa accgtatacg
    42721 ccgcagtggt aaggtgtgct tacgtccctt attattcata gtgaaagcat gccggattgc
    42781 ggctaatgat gagtaaaagg aaatccgttg cagatgattg tgcgcatact gctgctgttt
    42841 atcgctctgt tcacctttgg tgcgcaggcg caggctatca aggaaagcta tgcctttgcc
    42901 gtactgggcg aaccccggta cgcatttaat ttcaaccatt ttgattatgt gaaccccgcc
    42961 gcgccaaaag gtgggcaaat aacgttgtct gccctcggca ccttcgataa tttcaaccgc
    43021 tatgcactgc gcggcaatcc gggcgcacgc accgagcagc tgtacgacac gctatttacg
    43081 acttccgatg acgaaccagg cagttattac ccgctgattg ctgaaagcgc acgctatgct
    43141 gacgattatt cctgggtgga ggtcgctatt aatccacgcg cccgttttca tgatggttcg
    43201 cccattactg cccgcgatgt agagtttact tttcaaaaat ttatgaccga aggcgtgccg
    43261 caatttcgtc tggtctacaa aggcaccacc gtcaaagcca ttgcgccgtt aaccgtgcgc
    43321 attgagttag ctaaacccgg caaagaagat atgctgagtc tgttttcgct gccggtcttt
    43381 ccagaaaagt actggaaaga tcacaaactt agcgacccgc tcgccacgcc tccgcttgcc
    43441 agtggtccgt accgcattac gtcctggaaa atggggcaaa atattgtcta ttcccgcgtg
    43501 aaagattact gggcagcaaa cttaccggta aaccgtggac gctggaattt cgacaccatt
    43561 cgctacgatt attacctcga tgataatgtc gcctttgaag cgtttaaagc aggtgccttt
    43621 gatttgcgta tggaaaacga cgccaaaaac tgggccacgc gctataccgg taaaaatttc
    43681 gataaaaaat acatcatcaa agatgagcaa aagaacgaat cagcccagga tacgcgctgg
    43741 ctggcgttta atatccaacg tccggtattc agcgatcgcc gggtgcggga agcgatcact
    43801 ctcgcctttg actttgaatg gatgaacaaa gcgttgtttt acactgcctg gagtcgcacg
    43861 aacagttatt ttcagaatac cgaatacgcg gccagaaatt accccgacgc cgcggagctg
    43921 gtgcttctgg caccaatgaa aaaagatcta ccgccagaag tcttcacgca aatctaccag
    43981 ccgccggtat ccaaaggcga tggctacgat cgtgacaacc tgttaaaagc cgacaaactt
    44041 cttaacgaag caggctgggt gctgaagggt cagcaacgcg ttaatgccac aacgggtcag
    44101 ccactcagct ttgaattatt gcttcccgca agcagcaata gtcagtgggt attaccgttc
    44161 cagcacagcc tgcaacggct gggtatcaac atggacattc gcaaggtgga taactcgcaa
    44221 atcaccaacc gcatgcgcag tcgcgactat gacatgatgc cgcgcgtatg gcgggcgatg
    44281 ccgtggccca gttccgattt acagatttcc tggtcatcgg aatatatcaa ttccacttat
    44341 aatgcccccg gcgtgcaaag cccggttatc gactcgctga tcaaccaaat tattgccgcg
    44401 cagggaaata aagaaaaatt actgccgttg gggcgagcac tggatcgcgt attaacgtgg
    44461 aattattaca tgctgccaat gtggtatatg gcggaagacc gtctcgcctg gtgggataaa
    44521 ttctcccaac ccgctgtacg ccctgtttac agtttgggta tcgatacctg gtggtatgac
    44581 gttaataaag cggccaaact gccgtcagcc agacaacagg gagagtagat gggcgcttat
    44641 ctgattcgcc gtctgttgct ggtgatccca acgttatggg cgattatcac tatcaacttt
    44701 ttcatcgtgc aaattgcgcc tggcggtccg gtcgaccagg ccatcgccgc cattgagttt
    44761 ggtaatactg gtgtattacc cggtgcaggc ggtgaaggtg ttcgcgctag ccatgcacaa
    44821 acgggcgtcg gtaatatcag cgacagtaat taccgtggcg gacgcggatt agatccagaa
    44881 gtgatcgccg agatcactca tcgctacggt ttcgataagc cgatccacga acgttacttc
    44941 aaaatgctct gggactacat ccgctttgat tttggcgaca gcctttttcg cagcgcctcg
    45001 gtgctgacgc tgattaaaga cagtctgccg gtctccatca ccctcggatt gtggagcacg
    45061 ctgattatct atctggtgtc gattccgtta ggcattcgca aagctgttta taatgggagc
    45121 cgctttgacg tctggagtag cgcatttatc atcatcggct acgccattcc ggcctttttg
    45181 tttgccatcc tgctgattgt ctttttcgca ggcggcagct atttcgacct gttccctcta
    45241 cgcggcctgg tttccgctaa ctttgattcg ctgccgtggt atcagaaaat caccgattat
    45301 ctgtggcata tcacgctgcc ggtgctggcg actgtgattg gtggctttgc agcgctgacc
    45361 atgctgacaa aaaactcatt ccttgatgaa gtgcgtaagc aatacgtggt gacggcacgt
    45421 gcgaaagggg taagtgaaaa aaatattctc tggaaacatg tgttccgcaa cgccatgctg
    45481 ctggtgattg ccggttttcc ggcgacgttt atcagcatgt tttttaccgg ctcgctgctg
    45541 attgaggtga tgttttcact caatggtctt ggtttactgg gctacgaagc gaccgtctcg
    45601 cgcgattatc ctgtaatgtt tggtaccttg tatattttca ccctgattgg cctgctgctg
    45661 aatattgtca gtgatatcag ctatacgctg gtcgatccgc gtatagattt tgagggacgt
    45721 taatgtcgcg actcagcccc gtcaatcagg cccgttgggc gcgttttcgt cataaccgtc
    45781 gcggctactg gtcgttatgg attttcctcg tcttatttgg tttgagtttg tgttctgaac
    45841 ttatcgccaa cgataaaccg ttgctggtac gttatgacgg cagttggtat ttcccgttgt
    45901 tgaaaaacta cagcgaaagc gattttggcg gcccgctggc aagccaggct gattatcagg
    45961 acccgtggct gaaacagcgg ttggaagata aaggctgggt actgtgggca ccgattcgct
    46021 ttggtgctac cagtatcaac tttgctaccg ataagccctt cccttctcca ccctcccggc
    46081 aaaactggct gggaacggat gccaatggcg gcgatgtgct ggcgcgcatt ctctatggca
    46141 cgcggatctc agttctgttt ggcctgatgc tgaccctctg ctccagcgtg atgggcgtgc
    46201 tggcgggggc gctacaaggc tattacggcg gtaaagtcga tctctggggg caacgtttta
    46261 ttgaagtatg gtcggggatg ccgacgctgt ttttgattat tttactttcc agcgtcgtac
    46321 agcctaactt ctggtggctg ctggcaatta ctgtcttgtt tggctggatg agtctggtcg
    46381 gcgtggtgcg ggcggagttt ttacgtaccc gtaatttcga ctacatccgc gcggcgcagg
    46441 cgcttggcgt cagcgatcgc agtatcatcc tgcgtcatat gttgccaaat gccatggtcg
    46501 ctaccctcac ctttttaccg tttattttat gtagttcgat aaccaccctg acctcactcg
    46561 atttcctcgg cttcggtctg ccgctcggtt caccgtcact cggcgaactg ctgttacaag
    46621 ggaaaaataa ccttcaggcc ccgtggcttg ggatcaccgc cttcttgtcg gtggcgatat
    46681 tgttgtcttt gctgatcttt attggtgaag ccgtccgcga cgcatttgat cctaataagg
    46741 cggtgtagca tgacgcaaac tttgttagcg attgaaaatt tgtcggtggg ttttcgccat
    46801 caacaaaccg tacgtacagt agtcaatgat gtttcactac agattgaggc tggcgaaacg
    46861 ctggcgctgg tgggtgagtc tggttcaggc aaaagcgtta ccgcgctgtc aattttacgc
    46921 ctgctccctt ccccgccggt tgaatatctc tccggcgata ttcgttttca tggcgaatcg
    46981 ctgcttcatg ccagcgatca aacgttgcgc ggtgtacgcg gtaataagat cgccatgatt
    47041 tttcaggagc cgatggtgtc attaaatcca ttgcataccc tggaaaaaca gctttatgaa
    47101 gtgctttcac tccaccgcgg gatgcgtcgg gaagcggctc gtggcgaaat tcttaactgc
    47161 cttgatcgcg tcggtatccg ccaggcggca aaacggctga cagattatcc gcatcagctc
    47221 tccggcggcg aacgccagcg ggtgatgatt gcgatggcgc tgttaacgcg accggaatta
    47281 ttaattgccg atgaaccgac caccgcactg gacgtctctg tccaggcgca gattttacag
    47341 ctgttgcgcg aactgcaagg cgagctgaat atgggcatgc tgtttattac tcataacctc
    47401 agcattgtca gaaaactggc ccaccgcgtg gcggtaatgc ataacggtcg ctgtgtcgag
    47461 caaaataacg ctgctacgct atttgcctca cccactcatc cttacacaca aaagctactc
    47521 aacagtgaac catctggcga cccggtgcca ttgccagaac ctgcctctac gttgctagat
    47581 gttgaacaac ttcaggttgc cttccccatt cgtaaaggga tcttgaagcg cattgtggat
    47641 cataatgtgg tggtgaaaaa catcagtttt acgctacgtg cgggtgaaac actgggttta
    47701 gtgggcgagt ccggttccgg gaaaagcacg acggggctgg cgctgctgcg actgattaac
    47761 tctcagggca gcatcgtctt tgacggtcag ccactgcaaa atttaaatcg ccgccagctg
    47821 ttacctattc gtcatcgcat tcaggtggta tttcaggatc caaactcctc gctcaaccca
    47881 cgactcaacg ttttgcagat tattgaggaa ggcttacggg ttcaccagcc gacgctttcc
    47941 gtcgcacaac gcgaacaaca agtgatagcc gtgatgcatg aagtgggatt agatcctgaa
    48001 acacgccacc gttatccggc ggagttctct ggtggtcagc ggcaacgtat tgcgattgcc
    48061 agggcgttaa ttcttaagcc ctcgctgatc attcttgatg aaccaacatc atcgctcgac
    48121 aaaacggtac aggcgcaaat attgacgcta ttgaaatcat tgcaacaaaa gcatcaattg
    48181 gcctatttgt tcatcagtca cgatttgcac gttgtccgcg cgttatgtca tcaggttatc
    48241 gtactgcgac aaggggaagt agtggaacaa ggaccgtgcg cgcgcgtgtt tgccgcaccg
    48301 cagcaggagt atacgcgtca gctactggcg ttgagctgac gcttaaaaag gattgtagtt
    48361 tgagaagggt tcggcaattg ccacaccaaa atttttcaat cggcatgttg cagcaaactc
    48421 gtcctggcga tttacaaaca ggcacggctc accttcacac tccagtaccg agcatggaac
    48481 ttcaatgtcg cttaacgcct ggctgagttt gtacatcacc gaccatgcat tatcaccatc
    48541 cgggctaagc aatttaagcg ccaccaggct gttgtcaccg cacggtccat tttgcggaat
    48601 cggttcaacc ttcgaacctg cgaaaccagc agaccagcga tagttctgcg gcagtcgatg
    48661 gacgattgag agttgtaatg aagtcactta ttttccccgg aagcacattt acttcacaat
    48721 ttatttacat caattttaac acatcatcaa caatccgtct ttatacagat cgtaaagatt
    48781 gatgcctcgc ctgcgtggcc tctatggcac tgatttaaat aatatctgcg ggcgtggtca
    48841 cgtttgcggg gctatatgta cccgtttctg cgatctaact caaccttttt aactacaatg
    48901 atgtgacttt ttacataaat tgattttaca taaaataaac atatatcggg ggaatgatag
    48961 atttgtggtt gacatgcatc aacaaaggaa gccttttagc ttcctcgttg tgcaatagat
    49021 caccgttttt tcggccgact ggcgtacaga cagaagagaa tggaactggt tgcgcagaat
    49081 gcaattgacc aaatcatcgg ccatgcagag ttaaaggtcg caagagaaag taatgcgcca
    49141 acaattgccc ctatgccgaa acggaaggtt cctgccagcg aagatgccgt tcccgccata
    49201 tggggaaact catcaagaat gaccgccatc gcattggatg acaccatcga cacacagccc
    49261 acaaacgccg caacgccaac caccagagac cagaatccca gccccagcag cgcactgatg
    49321 accatccacg ccgccataat aaactgtatc cacaaccccg agcggaacat atttaacgcg
    49381 ccaatgcggc gaacgaagcg gctgttaaag atagtcatca cgaacagaaa aacaatgttt
    49441 agcgcaaagt aataaccaaa gttttccggc gcgacgtggt taatttcaat gtagacaaac
    49501 ggtccggcgc ttaagaacga gaacatcccg gcaaagctga aaccactggc aagcatataa
    49561 ctcaggacac gcttatgacg gaacagcgcc gcaaagttac caatagtagt acgaatgtga
    49621 aaaggctggc gacgctccgg tggtaaggtt tctttgatca gaaagaagat cattgccgaa
    49681 gccagaatcg ccgccacagc gaggatccag aagatgtaat gccagctcag ccacaccagc
    49741 acccagccgc caactatcgg tgccatcagc ggtgcaatgg tcgtcaccag catgacaaac
    49801 gacatcatcc gcgagaactc ttctttcggg tagatatcac gcatcaaagc gttgataacc
    49861 acgctggccg cagccgcagc cagcccgtgg aagaaacgca tcacaatcag ctgatcgatg
    49921 gtttgtgcca acgcacacgc caccgcggcg gcggcaaaca ccagcgtacc gccaagaacc
    49981 accggcttac gcccgaagct gtctgccatc ggcccgtaga ttaactgccc caacgcaaag
    50041 cccagaatat aagtactgag ggtcatctgc gtactgcccg ccggtacacc aaattgcgct
    50101 gaaattaccg gtagcgcagg cagatacata tcaatcgaca gcggcatcaa catggccagc
    50161 aggccaagga taaaaacaat agcaaacgac gaatgctgtc gggtggtcac aacgggctcc
    50221 tgaaagtcat tgaaaagtta gacgacgctg gcaatttctt cttcagttaa cggacgatat
    50281 tcaccggggg ctaaatcagc atccagcgta atgccgccaa tacgttcacg atgcagctca
    50341 accacatggt tacccacggc ggcgaacatg cgtttcacct gatgataacg cccttcgctg
    50401 atggtcagac gaacctgcgt tggggtaatc acttccagca ccgccggctt agtgagatct
    50461 ttttcgttat gcagctgcac gcctttagca aattgctctg ccgtatcgtc agctacgggt
    50521 gattccagcg tcaccagata ggtcttctcg caatgatggc gcggagaagt aatgcggtgc
    50581 gaccactgac catcatcagt cattagtacc agaccggtgg tatcgatatc cagccgccct
    50641 gcagcgtgca gtttccacgc taccggttca tcaagaaaat agagcaccgt tgggtgatcc
    50701 gggtcgtccg tggagcaaac atagccctga ggcttattga gcatgaagta acgtggaccg
    50761 tgttgctgcg ccagcgggtt gccatcgtaa gcgacatcat gttcagggag cagtttgaac
    50821 gctgcattac ggacgatttc gccatcgacg gtgacacgat tgccgcggat ttcacgcccg
    50881 gcaatagcac ggctaacgcc gagttgctgt gcgataaatt tatcaagtcg catgtgtgtg
    50941 attttgcctg taaaaaacgg aggtcgggta atgacccgaa aatctgaact gttgtctgcc
    51001 cagtatagcg gtctaataac atccctcaag ggaaaaagat ccgtggcata ctattagcag
    51061 aataatctac ctatgcgaga ccatgatttt tacacttcgc ccatatcagc aagaagccgt
    51121 ggatgccacg ctcaaccatt ttcgtcgtca taaaacccct gccgttatcg tgctgcccac
    51181 cggcgcaggt aaaagcctgg tgatagcgga actggcacgg ctggctcgtg gtcgcgtact
    51241 ggtgctggca cacgttaaag aactggtggc gcaaaaccat gcaaagtatc aggcgctggg
    51301 gctggaagcc gatatttttg ccgccgggct aaagcgcaaa gagagccacg gtaaagtggt
    51361 atttggcagc attcagtcgg tcgcccgtaa tcttgatgcc tttcagggtg aattttcgct
    51421 gttgattgtc gatgaatgtc accgtattgg tgacgatgaa gagagccagt atcagcaaat
    51481 cctcactcac ctgaccaaag tgaatcccca cttacgcctg ctggggctga ctgccacgcc
    51541 ttttcgatta ggcaaaggct ggatctacca gttccattat cacggcatgg tacgcggcga
    51601 tgagaaagcc cttttccgtg actgcattta tgagctgccg ctgcgttata tgattaaaca
    51661 cggctatctg acgccgccag aacgactgga tatgccagta gtgcaatacg atttcagccg
    51721 cttgcaggca cagagtaacg ggctgttcag cgaagccgat ctcaaccgtg agctgaaaaa
    51781 acaacaacgt attaccccgc acatcatcag ccagattatg gagtttgctg caacgcgcaa
    51841 aggggtgatg attttcgccg ccaccgttga acacgcaaaa gagattgtgg gattactacc
    51901 caccgaagat gctgcactga ttactggcga cacccccggc gctgagcgcg atgtgttaat
    51961 tgaaaatttt aaagcccagc gttttcgcta tctggtcaac gtcgcggtac tgaccaccgg
    52021 atttgacgcc ccgcacgtcg atcttatcgc cattctgcgc cctaccgaat cagtgagtct
    52081 ttaccaacaa attgtcgggc gcggtctgcg tctcgctcct ggcaagactg attgcttaat
    52141 tcttgattat gcgggtaatc ctcacgatct ctacgcgccg gaagttggta caccgaaagg
    52201 caaaagtgac aacgttccgg tacaggtttt ctgccctgcc tgcggttttg ccaacacctt
    52261 ttgggggaaa acgaccgccg acgggacatt gattgaacac tttggtcgcc gctgtcaggg
    52321 atggtttgaa gatgacgacg gtcatcgcga acagtgtgac ttccgtttcc gttttaaaaa
    52381 ttgcccgcaa tgtaacgcag aaaatgatat tgccgctcgc cgctgccgcg aatgtgacac
    52441 ggtactggtt gatccggatg atatgttaaa agcggcgcta cgactgaaag atgcgctggt
    52501 attacgctgt agcggcatgt ctttgcagca tgggcacgac gagaaaggcg aatggttgaa
    52561 aatcacctat tacgatgaag acggcgcgga tgtgagtgag cgtttccgtc tgcaaacgcc
    52621 cgcccagcga actgccttcg agcagctttt tatccgcccg catacgcgca caccgggcat
    52681 ccctctgcgc tggatcaccg ccgccgatgt cctcgcccag caagccttat tgcgacaccc
    52741 ggattttgtc gtcgcccgca tgaaaggcca gtactggcaa gtgcgtgaaa aagtgttcga
    52801 ttacgaaggt cgttttcgtc gggcgcacga attacgcggt taatggtagt tttgattgat
    52861 gtataaggcg attgagtata gaatctcgcc cgcttttgca tacgcaaagc agatcactta
    52921 cctgttgctg ggtcgcctgt agcaggatta atttaagaga gaaagaaatg tttactatca
    52981 acgcagaagt acgtaaagag cagggtaagg gtgcgagccg ccgcctgcgt gccgctaaca
    53041 agttcccggc aatcatctac ggtggcaaag aagcgccgct ggctgtcgaa ctggatcacg
    53101 acaaagtcat gaacatgcaa gttaaagctg aattctacag cgaagttctg accatcgttg
    53161 ttgacggtaa agaaatcaaa gttaaagctc aggacgtaca acgtcacccg tacaaaccga
    53221 agctgctgca catcgacttc gttcgcgctt aattgctgaa taagttgtaa aaaaccccgc
    53281 tccggcgggg ttttttgtct ctgcaaatta tgcctgatta cggtattgct attttttgca
    53341 ggccagataa ggcgttcacg ccgcatctgg cattcagaac acaaaaccga ttaattgccg
    53401 ccagacgtcc ggcgctgcaa ttgatcgcgc aagttcggcg gcgtgccttt aatggtcagg
    53461 gtatcggtcg ccggatccca gaagatgcgt tcacctaaca gcatcgcatc aaagttaata
    53521 gtcaagccac cgccgctacc ggcaaacttc gtcaactgac gcagtgtgct acggtctgcc
    53581 gggaagctct cttccagttc gtagcctttt tcagccgcaa actccgtgaa gctcacttcg
    53641 ctgacgcctg ccagctcttt cgacagcgat tccagttcaa tctcttcacc tgcctgcagc
    53701 tgctcattac agtagctata aacctgctgg cgcacgttct gtcgctctgc tttatccagt
    53761 tgtgcttcgg cagtgaaatc atcgaccgct tgcaacagcc cacggttttg cgctttcgcg
    53821 tttaaccctt cgctggcacc gaggaaatcc ataaagaaat ccgccacttt gcgccctact
    53881 cgccctttca ggaaagtgag atagcgggtc gactctggat tggtttccca ctcggttaaa
    53941 tcgatacgcg caacaatatc cgcatgattg atatcaagat aatgggttgg gttgatgtcg
    54001 agattttcgt taacacgcat actgctcagg ttgctcagaa ctgccaccag cagatactcc
    54061 accgccagat agcgatagtg gcaaaacagc acgaatccac cgtcagcaaa aggatatttc
    54121 gctaattcgt cacgcaggcg accggttgcc gcgcggctaa atgccagaaa gtcctcttca
    54181 ccctgacgct gtaagcgcag cgtctgcgcc agttcactct cttcgctaaa caagccgtaa
    54241 gctttatttt tggcgctata gacccgatgc agttctgcca ccatctcaac gacggtttct
    54301 gtcggttcca gcaatgaatc gcgcaacacc agctcaaggt tctgctcatc acgcttgata
    54361 agctggtgca gagcaatctg gttgatatcc agactcatga taaactctcc tttaagaccg
    54421 ggcggtattc aaccaccgcc ggttaagcga cgcaataaaa gatggcggtc attttacaga
    54481 aggcagcgta acgagaatga tttaacgcat aaaaaagcag aaaaaaaacc gttgctacgg
    54541 taatatgttg ccctttcatc aactaactga tttcgattta tgccacaaat ttcccgctac
    54601 agtgatgaac aggttgaaca attgctcgca gagctgctca acatactgga aaaacataag
    54661 gctccgaccg acctttccct gatggtgtta ggcaacatgg tcactaacct tatcaacacc
    54721 agcattgccc cggcccaacg ccaggcaatt gccaactctt ttgcccgcgc cttacagtcc
    54781 tctatcaacg aagacaaagc gcactaaggg aaacagataa caggttatgg taactcatcg
    54841 tcagcgctac cgtgaaaaag tctcccagat ggtcagttgg gggcactggt ttgcactgtt
    54901 caatattctg ctttcgctcg tcattggcag ccgttacctg tttatcgccg actggccgac
    54961 aacgcttgct ggtcgcattt attcctacgt aagcattatc ggtcatttca gcttcctggt
    55021 gttcgccacc tacttgctga tcctcttccc gctgaccttt atcgtcggct cccagaggct
    55081 gatgaggttt ttgtccgtca ttctggcaac ggcgggaatg acgctattac tgatcgatag
    55141 cgaagtcttt actcgtttcc atctccatct taatcccatc gtctggcaac tggttatcaa
    55201 cccagacgaa aatgagatgg cgcgcgactg gcagctgatg ttcatcagcg tgccggttat
    55261 tttattgctt gaactggtgt ttgcgacgtg gagctggcaa aagctgcgca gcctgacgcg
    55321 tcgtcgacgc ttcgcgcgcc cgctggccgc attcttattt atcgccttta tcgcctcgca
    55381 tgtggtgtat atctgggccg atgccaactt ctatcgcccg atcaccatgc agcgcgctaa
    55441 cctaccgctt tcgtacccga tgacggcgcg acgttttctt gagaagcatg gtctgcttga
    55501 tgcgcaggag tatcaacgcc gtctcattga gcaaggtaat cctgacgccg tttccgttca
    55561 gtatccgtta agcgaactgc gctatcgcga tatgggcacc gggcagaatg tgctgttgat
    55621 tactgtcgat ggcctgaact actcacgctt cgagaagcag atgcctgcgc tggcaggttt
    55681 tgctgagcaa aatatttcgt tcacgcgcca tatgagctcc ggcaacacta cagacaacgg
    55741 catctttggc ctgttctatg gcatctcgcc gagctatatg gatggcattc tgtcgacccg
    55801 tacgcctgcg gcattaatta ctgcgcttaa tcagcaaggc tatcagctgg ggttattctc
    55861 atcagatggc tttaccagcc cgctgtatcg ccaggcattg ttgtcagatt tctcgatgcc
    55921 gagcgtacgc acccaatccg acgagcagac cgccacgcag tggatcaact ggctgggccg
    55981 ctacgcacaa gaagataacc gctggttctc gtgggtttct ttcaatggca ctaacattga
    56041 cgacagcaat cagcaggcat ttgcacggaa atatagccgg gcggcaggca atgtcgatga
    56101 ccagatcaac cgcgtgctca atgcactacg cgattctggc aaactggaca atacggtggt
    56161 gattatcact gccggtcggg gtattccgct gagcgaagag gaagaaacct ttgactggtc
    56221 ccacggtcat ctgcaggtgc cattagtgat tcactggcca ggcacgccgg cgcagcgtat
    56281 taatgctctg actgatcata ccgatctgat gacgacgctg atgcaacgcc tgctacatgt
    56341 cagcacacct gccagcgaat attcgcaagg tcaggatttg ttcaaccctc aacgccgtca
    56401 ttactgggtt accgccgcgg ataacgatac gctggcaatt accaccccga aaaagacgct
    56461 ggtgctgaac aataacggta aataccgtac ttacaactta cgtggtgaaa gagtgaaaga
    56521 tgaaaaacca cagttaagtt tgttattgca agtactgaca gacgagaagc gttttatcgc
    56581 taactgatta attataaatc agttagcaaa atatcttact tgcaatcggt gtggaaaacg
    56641 gtagtattag cagccacgag tcggcacgta gcgcagcctg gtagcgcacc gtcatggggt
    56701 gtcgggggtc ggaggttcaa atcctctcgt gccgaccaaa aatcccaaga aaaaaccaac
    56761 cattacggtt ggttttttta tatctgcaat taattcgata aacagaccgt gacacatcac
    56821 ggcctgttta ttttctgtta tcagaacgtc cagaccacac ccgcctgagt attccacggc
    56881 gattctaccc ctgcgccatt gccataactg actgacaaat gaccgcttaa cgtcggggta
    56941 aacgatgacc ttatcccagc ctgataaacg ccacgggttc cagccacatc attattaaat
    57001 ttgccatcgt cattaacttt cacctggtta gaatcggcgt attcctgacg tacggcggct
    57061 ttcagccagg gttccagcgt cgtaccgttt tgcaggtcca tgtgatagct taccgccgtt
    57121 cccgcttcag cccgtaatat gcgggtattt cccacatccg cgcgcatgcc gtttgataac
    57181 gtgtagtcct gaccatctgt ggtaaagccg gtaaaggcca gataaggtct aacactccac
    57241 aatccgtcaa cccaacggaa cccgctctcg acatgagcac ccgcgccgtt actattgtaa
    57301 tcgccaaacg ctgttgcccc attactcatc ttgccatgga tggtgttggc aaaacggtca
    57361 actttcacca ccccatcaac ataggcaccg ttctgatgct cccaaccggc ataagccccc
    57421 agggtatagc tatcgacatt gcctttgccg ccgcgatcaa aaccaatatc agaatgagag
    57481 taaccaaaga acaagccgcg aattgtactg ctttcttcac gggagaaacg gctatcgata
    57541 ccgagcgtca gccccgtcaa tgtttgctca aagccagctc ccgcatcagt ggtcacgttg
    57601 ttgcgggtgt taattgccga actccacatc gccgtatcgt aattaacgcc ttttacgcta
    57661 ccaagacgct cacgcacggt gtccagttct gcatcaaata ccagcggttg tgctgccgcc
    57721 atattcagca catcagtggt tgaaggggta atttgcgcgc gattctctgc cagactccag
    57781 ctatggttgc cattatccag caaggtatat tcatacgtac cgatatcaac aacgcctccg
    57841 gcattgccca acgtaaatgc agcatcaccg ccgcccgtcg ttaccagtgt aaggctatct
    57901 cctgctgccg ggctggcacc ggtgtccgta acgaatattt tgaaatcacc tgttgcctga
    57961 ccggtgacgt tgagctgatc gctctgatga ttagccatat cggtacgcat ataaaaattg
    58021 ccgtttcccg acagggtatt ggtggtcaac gtaatgaaat tttccgcact tgccgtcact
    58081 gatgaacgag tcactggctc atccatcata atcacatttg cgtcagacat cgcaaggttg
    58141 gctaagttga ggagggtgtt ttggttcgtc gtagtgatat cggcaatgat ggtccatgag
    58201 ctaccatcga gcgaaacatc cgctttgctg gtatccacgg caccatgcgt tcttaaagaa
    58261 gcgccctcag aaaccacgac actacccacc aacatagcgg gtgcataatt tatttgcggc
    58321 ttcatgacct caagaatgcc atcattccct ctgactgaaa cgttaaccat cgtgccagcc
    58381 cagacattag cgcggccatt gttgataacc atattttcag agatggcttt agaggaatac
    58441 gtgatacttc cattctgatc tgatcgaccg agatcataca ccgcatttgc ctgcactctc
    58501 gtaccagtat cctttcccag cgattgcata gtggcatgct catcaaggat agtgtcaatg
    58561 gcctgcgtgt cctccataac aatgagcccg gaaccatcat ccagttcata attttttgac
    58621 acaccatctt ttatactaaa ttggccttta ctgtttgtac cactcacttc cagcgcattc
    58681 gttgagacaa ttaattttcc gcctgctttt ttatcaacgc cagttgcagt cccgccatcc
    58741 ataacctcca gtaagccgcc attatccaca gtggtattat aagcgaagtc attttcttca
    58801 actcgcaaac ttccgccgtt ttccaacagc atattattag caataccatt cttgatatcg
    58861 aactgaccga gacggtttgt tccgaatacc tccatggccc gcgtggttgt tttaatcgca
    58921 ccgcctgctt tctgatctac cgcaagcgca aatcccccct ctttaacctc cagtagtcct
    58981 cccttttcga tagcggcaaa gacggtcccc ccatcttttt caacgattaa gcgcccgcct
    59041 ttaatcgtag gttcattcgc cgcgccataa acctgtagca caccattatt gagggtagtc
    59101 tggtttgccg cgccacccat ttgaacaatt tgataaccat catttaatac tgagtattct
    59161 gcggtgccat tcatttcaat gtactgatac ccgccgttaa tttcagtatt actacttata
    59221 ccaaattctt taatatgctg ttctccgcca ggattgattt tcgtattatt ggcagtccca
    59281 taaaccagct ggatatcttt ttccaggaca acaccatcaa ctgtctcacc atactcaact
    59341 gttgatgcca atgctatggg tgaatataac gctgtagcca ccagaacaga tattgcggaa
    59401 cgacaaagag aaacagaacc agattgatgc attgagcttt catcctatga aattaattgc
    59461 tgttaaaagc attgggtaaa gaaaataccc atagctccat acccggagtc agtttttaaa
    59521 aactgtttaa agaaatgcac aagtattgtg attgattttt tagttgtttt tcttgatgag
    59581 aagctgatgc aaaattccgt ctttataatg aaaatgatgc caaagcgaac gacaaggttg
    59641 tagttttcgc tacatgtcca tacataaaat ggggtaacat tcacgcgcct ggtagcgtta
    59701 ccaacgctac gctcaaacat aatgattcta ataaaacctc aggagactac tatgcctgaa
    59761 gcaacgcctt ttcaggtgat gattgtggat gatcatccac ttatgcgacg cggtgttcgt
    59821 cagttactgg agcttgatcc tggctttgaa gtggtcgccg aagcgggcga cggcgcgagc
    59881 gcgatcgatc tggcgaatag actggatatc gacgtgatct tactggatct caatatgaaa
    59941 ggtatgagtg gcctggatac cctcaatgcc ttgcgcaggg atggcgttac cgcgcaaatt
    60001 attatcctga ccgtatcaga tgcctccagc gatgtctttg cgctgataga cgcaggcgca
    60061 gacggttatc tgttgaaaga tagcgacccg gaagtgttgc tggaagcgat tcgtgccgga
    60121 gcgaaaggca gcaaagtctt tagcgaacgc gtcaatcagt acttacgtga acgtgaaatg
    60181 tttggcgcgg aagaagatcc cttcagcgtg ctgacggagc gcgagctgga tgttctgcac
    60241 gagctggcac aggggctgtc aaataaacag attgcctcgg tgttgaatat ttccgagcag
    60301 acagtaaaag tacacattcg caatctgctg cgtaaactca atgtccgctc acgcgtggcg
    60361 gccaccattc tgttcctgca acaacgcggg gcacaataaa aatagcccga tggcatcacc
    60421 atcgggcctc tttttattta ctctcctgcg gcgacaaatg ttgcatcgcc tgcgcgatac
    60481 tacgttcaat caccgcacgg cgagtatcgt tggcaggtaa gagtttcaac atcatctccc
    60541 acgcggcaac ggcttcgcca aatcgctgct gctcaaaggc attaaacgca tacatgctta
    60601 acacacggat attgctgtgg tcagttctca ccaactggcg tagcagttca ccaccgaggc
    60661 ggttgtcgtt gggatcagat gaacgtgtca acgcttcagc gtatccgagc gccgcatcac
    60721 tgttcttcgg atcgaggcga tatgcagtag cgtatgcatc ggtggcaata ctggcgttac
    60781 ccagcgccat gccaacgcgg cccaacataa tccagccttc tatatctccc ggattttttt
    60841 gcagttgagt acgcatcccc agcgccaggc gcgacatctc ttcttcgttg agcggatcgg
    60901 ctttcggatc cagcgccctg tccagtaacg ccggagcctg tgccgtggcc tgctgccaga
    60961 ttttcacctg ctgataattg cccgtctggt agtagctgac gccagccaca attaacgcca
    61021 ccacaatacc cggcagataa acaatatatc cggcacgctt accttccggc acgctttgtt
    61081 caggaaactc ttccggcacc acgcgtaccc gacgccgcga acgggcgtaa atgacccaac
    61141 cgccaatgcc aatagccact accggaagca cccacagcag cacggtcagc ggcgttaacg
    61201 gcggatcgta agtgacgaag ttgccgtaac gcgccaccat ataatcgaca atctctttct
    61261 tacttttacc ttcctgcatc agttcataca ctttctggcg caggtcggtg gcaatcatcg
    61321 agttggaatc ggcaatgctg ttgttctggc atttcgggca gcgtagttct tcagtgagtt
    61381 ggcggaactg ctgctcctgc gcttcatcct taaactgcaa cacgtcgatg gtcgccagcg
    61441 ctgagccgga gatcatcagc atcagcacgc ccaataaaaa cctcattgtg cggcctcctt
    61501 actgtatttc tcccacagcg gcttgatctc ttcttcccag acgcgaggat tgagatcgcc
    61561 cgcatggcga tagcgaatga tgccgttgcc gtcgatgagg aacgtttctg gcgcgccata
    61621 gacaccgaga tccagcccta acatgccatc gccatcaaac aggcttagcg cgtaaggatt
    61681 gcccagctct ttcagccagc tgattgcctt ctggcgatcg tctttatagt tcatgccgac
    61741 cacgcgaatg ccctgcgcag aaagctgatt cagatattga tgttccgcac ggcaggtcgg
    61801 acaccaggtc gcccagacgt taagcagcac aggtttgccc tgagtcagca catccgcctg
    61861 ataaaactgc cccggattgt ccagtgattc gaggcgaaac ttcggcactg gcttgccaat
    61921 gagcgccgat tccagattgg tcggatcatc cccttcggca ttacgcgcca gctgccacag
    61981 tagcgccgcg gcaatcgcca ggaagataat caacggaatt aacaatactt tgcgcttcat
    62041 acagcctccg gcgcagtttt ttgcggactc acgcgcttac gatagcgagg atcaaacagg
    62101 cacagca
//
LOCUS       DADXDL010000015        61197 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.015, whole genome shotgun sequence.
ACCESSION   DADXDL010000015 DADXDL010000000
VERSION     DADXDL010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 61197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 61197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..61197
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.015"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1268)
                     /locus_tag="IRB70_001235"
     CDS             complement(<1..1268)
                     /locus_tag="IRB70_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HBC0631176.1"
                     /translation="MNQQDIEQVVKAVLLKMQSSDTPPAAVHEMGVFASLDDAVAAAK
                     VAQQGLKSVAMRQLAIAAIREAGEKHARDLAELAVSETGMGRVEDKFAKNVAQARGTP
                     GVECLSPQVLTGDNGLTLIENAPWGVVASVTPSTNPAATVINNAISLIAAGNSVIFAP
                     HPAAKKVSQRAITLLNQAIVAAGGPENLLVTVANPDIETAQRLFKFPGIGLLVVTGGE
                     AVVEAARKHTNKRLIAAGAGNPPVVVDETADLARAAQSIVKGASFDNNIICADEKVLI
                     VVDSVADELMRLMEGQHAVKLTAEQAQQLQPVLLKNIDERGKGIVSRDWVGRDAAKIA
                     AAIGLKVPEQTRLLFVETTAEHPFAVTELMMPVLPVVRVANVADAIALAVKLEGGCHH
                     TAAMHSRNIENMNQMANAIDTSIFVKNGPC"
     gene            complement(1280..1567)
                     /gene="eutN"
                     /locus_tag="IRB70_001236"
     CDS             complement(1280..1567)
                     /gene="eutN"
                     /locus_tag="IRB70_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutN"
                     /protein_id="HBC0631177.1"
                     /translation="MKLAVVTGQIVCTVRHHGLAHDKLLMVEMIDPQGNPDGQCAVAI
                     DNIGAGTGEWVLLVSGSSARQAHKSETSPVDLCVIGIVDEVVSGGQVIFHK"
     gene            complement(1674..1967)
                     /gene="eutM"
                     /locus_tag="IRB70_001237"
     CDS             complement(1674..1967)
                     /gene="eutM"
                     /locus_tag="IRB70_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutM"
                     /protein_id="HBC0631178.1"
                     /translation="MEALGMIETRGLVALIEASDAMVKAARVKLVGVKQIGGGLCTAM
                     VRGDVAACKAATDAGAAAAQRIGELVSVHVIPRPHGDLEEVFPIGLKGDSSNL"
     gene            complement(2006..3022)
                     /gene="pta"
                     /locus_tag="IRB70_001238"
     CDS             complement(2006..3022)
                     /gene="pta"
                     /locus_tag="IRB70_001238"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBC0631179.1"
                     /translation="MIIKRCRELALRAPARVVFPDALDQRVLKAAQYLHQQGLATPIL
                     VANPFELRQFALSHGVAMDGLQVIDPHGNLAMREEFAHRWLARAGEKTPPDALEKLTD
                     PLMFAAAMVSAGKADVCIAGNLSSTANVLRAGLRIIGLQPGCKTLSSIFLMLPQYSGP
                     ALGFADCSVVPQPTAAQLADIALASAETWRAITGEEPRVAMLSFSSNGSARHPCVANV
                     QQATEIVRECAPKLVVDGELQFDAAFVPEVAAQKAPASPLQGKANVMVFPSLEAGNIG
                     YKIAQRLGGYRAVGPLIQGLAAPMHDLSRGCSVQEIIELALVAAVPRQTEVNRESSLQ
                     TLVE"
     gene            complement(3019..3822)
                     /gene="eutT"
                     /locus_tag="IRB70_001239"
     CDS             complement(3019..3822)
                     /gene="eutT"
                     /locus_tag="IRB70_001239"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization cob(I)yrinic acid
                     a,c-diamide adenosyltransferase EutT"
                     /protein_id="HBC0631180.1"
                     /translation="MKDFITEAWLRANHTLSEGAEIHLPADSRLTPSARELLESRHLR
                     IKFIDEQGRLFVDDEQQQPQPVHGLTSSDEHPQACCELCRQPVAKKPDTLTHLSAEKM
                     VAKSDPRLAFRAVLDSTIALAVWLQIELAEPWQPWLADIRSRLGNIMRADALGEPLAC
                     QAIVGLSDEDLHRLSHQPLRYLDHDHLVPEASHGRDAALLNLLRTKVRETETVAAQVF
                     ITRSFEVLRPDILQALNRLSSTVYVMMILSVAKQPLTVKQIQQRLGETQ"
     gene            complement(3819..4520)
                     /gene="eutQ"
                     /locus_tag="IRB70_001240"
     CDS             complement(3819..4520)
                     /gene="eutQ"
                     /locus_tag="IRB70_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutQ"
                     /protein_id="HBC0631181.1"
                     /translation="MKKLITANDIREAHARGELAMSVVLRASIITPEAREVADLLGFT
                     ITECDESTAVTTSVPASVPADKTESQRIRETIIAQLPEGQFTESLVAQLMEKVMKEKQ
                     SLEQGAMQPSFKSVTGKGGIKVIDGSSVKFGRFDGAEPHCVGLTDLVTGDDGSSMAAG
                     FMQWENAFFPWTLNYDEIDMVLEGELHVRHEGETMIAKAGDVMFIPKGSSIEFGTTSS
                     VKFLYVAWPANWQSL"
     gene            complement(4495..4974)
                     /gene="eutP"
                     /locus_tag="IRB70_001241"
     CDS             complement(4495..4974)
                     /gene="eutP"
                     /locus_tag="IRB70_001241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization acetate kinase EutP"
                     /protein_id="HBC0631182.1"
                     /translation="MKRIAFVGTVGAGKTTLFNALQGNYTLARKTQAVEFNDKGDIDT
                     PGEYFSHPRWYHALITTLQDVDMLIYVHGANDPESRLPAGLLDIGVSKRQIAVISKTD
                     MPDADVAATRKLLLETGFEEPIFELNSHDPQSVQQLVDYLASLTKQEEAGEKTHHSE"
     gene            complement(4987..5322)
                     /gene="eutS"
                     /locus_tag="IRB70_001242"
     CDS             complement(4987..5322)
                     /gene="eutS"
                     /locus_tag="IRB70_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutS"
                     /protein_id="HBC0631183.1"
                     /translation="MDKERIIQEFVPGKQVTLAHLIAHPGEELAKKIGVPDAGAIGIM
                     TLTPGETAMIAGDLALKAADVHIGFLDRFSGALVIYGSVGAVEEALSQTVSGLGRLLN
                     YTLCEMTKS"
     gene            5688..6758
                     /locus_tag="IRB70_001243"
     CDS             5688..6758
                     /locus_tag="IRB70_001243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001571749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBC0631184.1"
                     /translation="MKIHYLVTTLEAGGAEFAIPDIVTTLQDLGHEVKIYVCEPRDMG
                     AAPRLEAAGLSWCLLSNRRRSEPMLVAAYLAKIIHDKPDLIWTSLSWGTRIGQWVGRL
                     MGIPVISFKHSASVKPATWRMRNMSRLWIGDSETVAQYLHETMLIPKQQVLCWPFFQA
                     NPQAAQAQNWDGKSVLQLGSVGRLHEVKNYAGLITALASFVDKNPQLRSRIRLTILGE
                     GPEQEALQKTITQHALEDVVCLAGFSADVENFLAGLHVYIQTSRYEGMCLAAHEAMNA
                     GLAIITTPVGELKESVIDGHTGYTLNGELTPALEGVLNRIFSEPEELERYGQNVRQYV
                     LAKFSHENFVQSAINIVNRLIH"
     gene            6772..7674
                     /locus_tag="IRB70_001244"
     CDS             6772..7674
                     /locus_tag="IRB70_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009638890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631185.1"
                     /translation="MNCYTTDLWQIGIVQAPIQHIVASGSLDGFRIKWITPDKSLTFL
                     ADPFGLWKKGVLYLFAESYDYRTRRGDIIAYKLNADLDVIEQRTVLQEPWHLSYPFVF
                     EADNEIWMLPEGYKSGTLTLYRAIEFPWRWEKVPDFSFPCAAIDATPFYAQGKWWMFY
                     TPPLPKAARTDTLMLAHAPHFMGPWENVLQTAAHRNKSGARMGGTPFDHDGQIFLPTQ
                     DCSRTYGGALQMLTLDPQRLLTPEFAASVRLEVPASAAPFIAGMHTLSGVGDVTFIDA
                     KRHLKGSPQRLWVDLQRRIQKWIS"
     gene            complement(7722..10001)
                     /gene="maeB"
                     /locus_tag="IRB70_001245"
     CDS             complement(7722..10001)
                     /gene="maeB"
                     /locus_tag="IRB70_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxaloacetate-decarboxylating
                     malate dehydrogenase"
                     /protein_id="HBC0631186.1"
                     /translation="MDDQLKQSALDFHEFPVPGKIQVSPTKPLATQRDLALAYSPGVA
                     APCLEIEKDPLKAYKYTARGNLVAVISNGTAVLGLGNIGALAGKPVMEGKGVLFKKFA
                     GIDVFDIEVDELDPDKFIEVVAALEPTFGGINLEDIKAPECFYIEQKLRERMNIPVFH
                     DDQHGTAIISTAAILNGLRVVEKNISDVRMVVSGAGAAAIACMNLLVALGLQKHNIVV
                     CDSKGVIYQGREPNMAETKAAYAVVDDGKRTLDDVIEGADIFLGCSGPKVLTQEMVKK
                     MARAPMILALANPEPEILPPLAKEVRPDAIICTGRSDYPNQVNNVLCFPFIFRGALDV
                     GATAINEEMKLAAVRAIAELAHAEQSEVVASAYGDQDLSFGPEYIIPKPFDPRLIVKI
                     APAVAKAAMESGVATRPIADFDVYIDKLTEFVYKTNLFMKPIFSQARKAPKRVVLPEG
                     EEARVLHATQELVTLGLAKPILIGRPNVIEMRIQKLGLQIKAGVDFEIVNNESDPRFK
                     EYWTEYFQIMKRRGVTQEQAQRALISNPTVIGAIMVQRGEADAMICGTVGDYHEHFSV
                     VKNVFGYRDGVHTAGAMNALLLPSGNTFIADTYVNDEPDAEELAEITLMAAETVRRFG
                     IEPRVALLSHSNFGSSDCPSSSKMRQALELVRERAPELMIDGEMHGDAALVEAIRNDR
                     MPDSPLKGSANILVMPNMEAARISYNLLRVSSSEGVTVGPVLMGVAKPVHVLTPIASV
                     RRIVNMVALAVVEAQTQPL"
     gene            10290..11240
                     /gene="tal"
                     /locus_tag="IRB70_001246"
     CDS             10290..11240
                     /gene="tal"
                     /locus_tag="IRB70_001246"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HBC0631187.1"
                     /translation="MNELDGIKQFTTVVADSGDIESIRHYHPQDATTNPSLLLKAAGL
                     SQYEHLIDDAIAWGKKNGKTQEQQVVAACDKLAVNFGTEILKIVPGRVSTEVDARLSF
                     DKEKSIEKARHLVDLYQQQGVEKSRILIKLASTWEGIRAAEELEKEGINCNLTLLFSF
                     AQARACAEAGVFLISPFVGRIYDWYQARKPMDPYVVEEDPGVKSVRNIYDYYKQHHYE
                     TIVMGASFRRTEQILALTGCDRLTIAPNLLKELQEKVSPVVRKLIPSSQTFPRPAPMS
                     EAEFRWEHNQDAMAVEKLSEGIRLFAVDQRKLEDLLAAKL"
     gene            11260..13263
                     /gene="tkt"
                     /locus_tag="IRB70_001247"
     CDS             11260..13263
                     /gene="tkt"
                     /locus_tag="IRB70_001247"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBC0631188.1"
                     /translation="MSRKDLANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWNDFL
                     KHNPTDPTWYDRDRFILSNGHASMLLYSLLHLTGYDLPLEELKNFRQLHSKTPGHPEI
                     GYTPGVETTTGPLGQGLANAVGLAIAERTLAAQFNQPDHEIVDHFTYVFMGDGCLMEG
                     ISHEVCSLAGTLGLGKLIGFYDHNGISIDGETEGWFTDDTAKRFEAYHWHVIHEIDGH
                     DPQAVKEAILEAQSVKDKPSLIICRTVIGFGSPNKAGKEEAHGAPLGEEEVALARQKL
                     GWHHPPFEIPKEIYHAWDAREKGEKAQQSWNEKFAAYKKAHPQLAEEFTRRMSGGLPK
                     DWEKTTQKYINELQANPAKIATRKASQNTLNAYGPMLPELLGGSADLAPSNLTIWKGS
                     VSLKEDPAGNYIHYGVREFGMTAIANGIAHHGGFVPYTATFLMFVEYARNAARMAALM
                     KARQIMVYTHDSIGLGEDGPTHQAVEQLASLRLTPNFSTWRPCDQVEAAVGWKLAVER
                     HNGPTALILSRQNLAQVERTPDQVKEIARGGYVLKDSGGKPDIILIATGSEMEITLQA
                     AEKLAGEGRNVRVVSLPSTDIFDAQDEEYRESVLPSNVAARVAVEAGIADYWYKYVGL
                     KGAIVGMTGYGESAPADKLFPFFGFTAENIVAKAHKVLGVKGA"
     gene            complement(13366..14409)
                     /locus_tag="IRB70_001248"
     CDS             complement(13366..14409)
                     /locus_tag="IRB70_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708305.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1176 domain-containing protein"
                     /protein_id="HBC0631189.1"
                     /translation="MRYRIFLLFFFALLPTSLVWAAPAQRAFSDWQVTCNNQNFCVAR
                     NTGDHNGLVMTLSRSAGAHTDAVLRIERGGLKSPDASEGEIAPRLLLDGEPLALSGDK
                     WRISPWLLVTDDTATITAFLQLIQEGKAITLRDGNQTISLNGLKAALLFIDAQQKRVG
                     SETAWIKKGDEPPLSVPPAPALKEVAVVNPTPTPLSLEERNDLLDYGNWRMNGLRCSL
                     DPLRREVNVTALTDDKALMMISCEAGAYNTIDLAWIVSRKKPLASRPVRLRLPFNNGQ
                     ETNELELMNATFDEKSRELVTLAKGRGLSDCGIQARWRFDGQRFRLVRYAAEPTCDNW
                     HGPDAWPTLWITR"
     gene            complement(14535..15110)
                     /gene="nudK"
                     /locus_tag="IRB70_001249"
     CDS             complement(14535..15110)
                     /gene="nudK"
                     /locus_tag="IRB70_001249"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose pyrophosphatase NudK"
                     /protein_id="HBC0631190.1"
                     /translation="MTQQITLIKDKILSDNYFTLHNITYDLTRKDGEVIRHKREVYDR
                     GNGATILLYNAKKKTVVLIRQFRVATWVNGNESGQLIETCAGLLDNDEPEVCIRKEAI
                     EETGYEVGEVRKLFELYMSPGGVTELIHFFIAEYSDSQRANAGGGVEDEDIEVLELPF
                     SQALEMIKTGEIRDGKTVLLLNYLQTSHLMD"
     gene            complement(15178..17157)
                     /gene="aegA"
                     /locus_tag="IRB70_001250"
     CDS             complement(15178..17157)
                     /gene="aegA"
                     /locus_tag="IRB70_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     AegA"
                     /protein_id="HBC0631191.1"
                     /translation="MNRFIMANSQQCLGCHACEIACVMAHNDEQHVLSQRHFHPRITV
                     IKHQQQRSAVTCHHCEDAPCARSCPNGAISHVDDSIQVNQQKCIGCKSCVVACPFGTM
                     QIVLTPVAAGKVKATAHKCDLCAGRENGPACVENCPADALQLVTDAALSGIAKSRRLR
                     TARQEHQPWHASTAAQEMPVMSKVEQMQATPARGEPDKLAIEARKTGFDEIYLPFRAD
                     QAQREASRCLKCGEHSVCEWTCPLHNHIPQWIELVKAGNIDAAVELSHQTNTLPEITG
                     RVCPQDRLCEGACTIRDEHGAVTIGNIERYISDQALAKGWRSDLSHVTKVDKRVAIIG
                     AGPAGLACADVLTRNGVEVTVYDRHPEIGGLLTFGIPSFKLDKSLLARRREIFSAMGI
                     HFELNCEVGKDVSLDSLLEQYDAVFVGVGTYRSMKAGLPNEDAPGVYDALPFLIANTK
                     QVMGLEELPEEPFINTAGLNVVVLGGGDTAMDCVRTALRHGASNVTCAYRRDEANMPG
                     SKKEVKNAREEGANFEFNVQPVALELNEQGHVCGIRFLRTSLGEPDAQGRRRPVPVEG
                     SEFVMPADAVIMAFGFNPHGMPWLESHGVTVDKWGRIIADVESQYRYQTTNPKIFAGG
                     DAVRGADLVVTAMAEGRHAAQGIIDWLGVKSVKSH"
     gene            17363..19063
                     /gene="narQ"
                     /locus_tag="IRB70_001251"
     CDS             17363..19063
                     /gene="narQ"
                     /locus_tag="IRB70_001251"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarQ"
                     /protein_id="HBC0631192.1"
                     /translation="MIVKRPVSASLARAFFYIVLLSILSTGIALLTLASSLRDAEAIN
                     IAGSLRMQSYRLGYDLQSGSPQLNAHRQLFQQALHSPVLTNLNVWYVPEAVKTRYAHL
                     NANWLEMNNRLSKGDLPWYQANINNYVNQIDLFVLALQHYAERKMLLVVAISLAGGIG
                     IFTLVFFTLRRIRHQVVAPLNQLVTASQRIEHGQFDSPPLDTSLPNELGLLAKTFNQM
                     SSELHKLYRSLEASVEEKTRDLHEAKRRLEVLYQCSQALNTSQIDVHCFRHILQIVRD
                     NEAAEYLELNVGDNWRISEGQPNPELPMQILPVTMQETVYGELHWQNSHVSSSEPLLN
                     SVSSMLGRGLYFNQAQKHFQQLLLMEERATIARELHDSLAQVLSYLRIQLTLLKRSIP
                     EDNATAQSIMADFSQALNDAYRQLRELLTTFRLTLQQADLPSALREMLDTLQNQTSAK
                     LTLDCRLPTLALDAQMQVHLLQIIREAVLNAMKHANASEIAVSCVTAPDGNHTVYIRD
                     NGIGIGEPKEPEGHYGLNIMRERAERLGGTLTFSQPSGGGTLVSISFRSAEGEESQLM
                     "
     gene            19227..22340
                     /gene="acrD"
                     /locus_tag="IRB70_001252"
     CDS             19227..22340
                     /gene="acrD"
                     /locus_tag="IRB70_001252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease AcrD"
                     /protein_id="HBC0631193.1"
                     /translation="MANFFIDRPIFAWVLAILLCLTGTLAIFSLPVEQYPDLAPPNVR
                     VTANYPGASAQTLENTVTQVIEQNMTGLDNLMYMSSQSSGTGQASVTLSFKAGTDPDE
                     AVQQVQNQLQSAMRKLPQAVQNQGVTVRKTGDTNILTIAFVSTDGSMDKQDIADYVAS
                     NIQDPLSRVNGVGDIDAYGSQYSMRIWLDPAKLNSFQMTAKDVTDAIESQNAQIAVGQ
                     LGGTPSVDKQALNATINAQSLLQTPEQFRDITLRVNQDGSEVRLGDVATVEMGAEKYD
                     YLSRFNGKPASGLGVKLASGANEMATAELVLNRLDELAQYFPHGLEYKVAYETTSFVK
                     ASIEDVVKTLLEAIALVFLVMYLFLQNFRATLIPTIAVPVVLMGTFSVLYAFGYSVNT
                     LTMFAMVLAIGLLVDDAIVVVENVERIMSEEGLTPREATRKSMGQIQGALVGIAMVLS
                     AVFVPMAFFGGTTGAIYRQFSITIVAAMVLSVLVAMILTPALCATLLKPLKKGEHHGQ
                     KGFFAWFNQMFNRNAERYEKGVAKILHRSLRWIVIYVLLLGGMVFLFLRLPTSFLPLE
                     DRGMFTTSVQLPSGSTQQQTLKVVEQIEKYYFTHEKDNIMSVFATVGSGPGGNGQNVA
                     RMFIRLKDWSERDSKTGTSFAIIERATKAFNKIKEARVIASSPPAISGLGSSAGFDME
                     LQDHAGAGHDALMAARNQLLALAAENPELTRVRHNGLDDSPQLQIDIDQRKAQALGVA
                     IDDINDTLQTAWGSSYVNDFMDRGRVKKVYVQAAAPYRMLPDDINLWYVRNKDGGMVP
                     FSAFATSRWETGSPRLERYNGYSAVEIVGEAAPGVSTGTAMDIMESLVKQLPNGFGLE
                     WTAMSYQERLSGAQAPALYAISLLVVFLCLAALYESWSVPFSVMLVVPLGVIGALLAT
                     WMRGLENDVYFQVGLLTVIGLSAKNAILIVEFANEMNQKGHDLFEATLHACRQRLRPI
                     LMTSLAFIFGVLPMATSTGAGSGGQHAVGTGVMGGMISATILAIYFVPLFFVLVRRRF
                     PLKPRPE"
     gene            complement(22439..22498)
                     /gene="ypfM"
                     /locus_tag="IRB70_001253"
     CDS             complement(22439..22498)
                     /gene="ypfM"
                     /locus_tag="IRB70_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YpfM"
                     /protein_id="HBC0631194.1"
                     /translation="MIERELGNWKDFIEVMLRK"
     gene            22879..23235
                     /locus_tag="IRB70_001254"
     CDS             22879..23235
                     /locus_tag="IRB70_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsC family reductase"
                     /protein_id="HBC0631195.1"
                     /translation="MVTLYGIKNCDTIKKARRWLEANNIDYRFHDYRVDGLDSELLNG
                     FINELGWEALLNTRGTTWRKLDETTRNKITDAASAATLMTEMPAIIKRPLLCAPGKPM
                     LLGFSESSYQQFFHEV"
     gene            23239..24366
                     /gene="dapE"
                     /locus_tag="IRB70_001255"
     CDS             23239..24366
                     /gene="dapE"
                     /locus_tag="IRB70_001255"
                     /EC_number="3.5.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020078199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinyl-diaminopimelate desuccinylase"
                     /protein_id="HBC0631196.1"
                     /translation="MSCPVIELTQQLIRRPSLSPDDAGCQALLIERLQAIGFTVERMD
                     FADTQNFWAWRGQGETLAFAGHTDVVPPGDADRWINPPFEPTIRDGMLFGRGAADMKG
                     SLAAMVVAAERFVAQHPNHAGRLAFLITSDEEASAHNGTVKVVEALMARNERLDYCLV
                     GEPSSIEVVGDVVKNGRRGSLTCNLTIHGVQGHVAYPHLADNPVHRAAPFLNELVAIE
                     WDQGNEFFPATSMQIANIQAGTGSNNVIPGELFVQFNFRFSTELTDEMIKAQVLALLE
                     KHQLRYTVDWWLSGQPFLTARGKLVDAVVNAVEHYNEIKPQLLTTGGTSDGRFIARMG
                     AQVVELGPVNATIHKINECVNAADLQLLARMYQRIMEQLVA"
     gene            24394..24594
                     /locus_tag="IRB70_001256"
     CDS             24394..24594
                     /locus_tag="IRB70_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpfN family protein"
                     /protein_id="HBC0631197.1"
                     /translation="MDWLAKYWWILVIVFLVGVLLNVIKDLKRVDHKKFLANKPELPP
                     HRDFNDKWDDDDDWPKKDQPKK"
     gene            complement(24675..25373)
                     /gene="ypfH"
                     /locus_tag="IRB70_001257"
     CDS             complement(24675..25373)
                     /gene="ypfH"
                     /locus_tag="IRB70_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311362.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBC0631198.1"
                     /translation="MKHDHFVVQSPDKPAQQLLLLFHGVGDNPVAMGEIGSWFAPLFP
                     DALVVSVGGAEPSGNPAGRQWFSVQGITEDNRQARVDAIMPTFIETVRYWQKQSGVGA
                     NATALIGFSQGAIMALESIKAEPGLASRVIAFNGRYASLPETASTATTIHLIHGGEDP
                     VIDLAHAVAAQEALISAGGDVTLDIVEDLGHAIDNRSMQFALDHLRYTIPKHYFDEAL
                     SGGKPGDDDVIEMM"
     gene            complement(25447..27462)
                     /gene="tmcA"
                     /locus_tag="IRB70_001258"
     CDS             complement(25447..27462)
                     /gene="tmcA"
                     /locus_tag="IRB70_001258"
                     /EC_number="2.3.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cytosine(34) acetyltransferase TmcA"
                     /protein_id="HBC0631199.1"
                     /translation="MAELTALHTLTAQMKREGIRRLLVLSGEEGWCFDHALKLRDALP
                     GDWLWISPQPVAENHCFPSALQTLLGREFRHAVFDARHGFDAAAFAALSGTLKAGSWL
                     VLLLPVWEEWDNQPDADSLRWSDCPDPIATPHFVQHFKRVITANNDAILWRQNQPFSL
                     AHFTPRTDWHPATGAPQPEQQQLLQQLLTMPPGVAAVTAARGRGKSALAGQLISRIAG
                     SAIVTAPAKAATDVLAQFAGEKFRFIAPDALIASDEQADWLVVDEAAAIPAPLLHQLV
                     SRFPRTLLTTTVQGYEGTGRGFLLKFCARFPHLHRFELQQPIRWAQGCPLEKMVSEAL
                     VFDDENFTHTPQGNIVISAFEQTLWRSEPQTPLKVYQLLSGAHYRTSPLDLRRMMDAP
                     GQHFLQAAGENAIAGALWLVDEGGLSQELSQAVWAGFRRPRGNLVAQSLAAHGSNPLA
                     ATLRGRRVSRIAVHPARQREGTGQQLIAGALQYTHDLDYLSVSFGYTGELWRFWQRCG
                     FVLVRMGNHREASSGCYTAMALLPMSDAGKQLAEGEHYRLRRDAQALAKWNGETLPVD
                     PLNDAVLSDDDWLELAGFAFAHRPLLTSLGCLMRLLQTSEMALPALRGRLQKNASDAQ
                     LCTTLKLSGRKLLLVRQREEAAQALYALDDVRTERLRDRITQWQFFH"
     gene            complement(27477..28340)
                     /locus_tag="IRB70_001259"
     CDS             complement(27477..28340)
                     /locus_tag="IRB70_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="neutral zinc metallopeptidase"
                     /protein_id="HBC0631200.1"
                     /translation="MRWQGRRESDNVEDRRNSSGGPSMGGPGFRLPSGKGGLILLIVV
                     LVAGYYGVDLTGLMTGQPVSQQQSTRSISPNEDEAAKFTSVILATTEDTWGQQFEKMG
                     KTYQQPKLVMYRGMTRTGCGAGQSIMGPFYCPADGTVYIDLSFYDDMKDKLGADGDFA
                     QGYVIAHEVGHHVQKLLGIEPKVRQLQQNATQAEVNRLSVRMELQADCFAGVWGHSMQ
                     QQGVLETGDLEEALNAAQAIGDDRLQQQSQGRVVPDSFTHGTSQQRYSWFKRGFDSGD
                     PAQCNTFGKSI"
     gene            complement(28508..29221)
                     /gene="purC"
                     /locus_tag="IRB70_001260"
     CDS             complement(28508..29221)
                     /gene="purC"
                     /locus_tag="IRB70_001260"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017458944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBC0631201.1"
                     /translation="MQKQAELYRGKAKTVYSTENPDLLVLEFRNDTSAGDGARIEQFD
                     RKGMVNNKFNYFIMSKLAEAGIPTQMERLLSDTECLVKKLDMVPVECVVRNRAAGSLV
                     KRLGIEEGIELNPPLFDLFLKNDAMHDPMVNESYCETFGWVSKENLARMKELTYKAND
                     VLKKLFDDAGLILVDFKLEFGLYKGEVVLGDEFSPDGSRLWDKETLEKMDKDRFRQSL
                     GGLIEAYEAVARRLGVQLD"
     gene            complement(29434..30468)
                     /gene="bamC"
                     /locus_tag="IRB70_001261"
     CDS             complement(29434..30468)
                     /gene="bamC"
                     /locus_tag="IRB70_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708316.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamC"
                     /protein_id="HBC0631202.1"
                     /translation="MAYSVQKSRLAKVAGVSLVLLLAACSSDSRYKRQVSGDEAYLEA
                     APLAELHAPAGMILPVTSGDYAIPVTNGSGAVGKALDIRPPAQPLALVSGARTQFTGD
                     TASLLVENGRGNTLWPQVVSVLQAKNYTITQRDDAGQTLTTDWVQWNRLDEDEQYRGR
                     YQISVKPQGYQQAVTVKLLNLEQAGKPVADAASMQRYSTEMMNVISAGLDKSATDAAN
                     AAQNRASTTMDVQSAADDTGLPMLVVRGPFNVVWQRLPAALEKVGMKVTDSTRSQGNM
                     AVTYKPLSDSEWHELGASDPGLASGDYKLQVGDLDNRSSLQFIDPKGHTLTQSQNDAL
                     VAVFQAAFSK"
     gene            complement(30485..31363)
                     /gene="dapA"
                     /locus_tag="IRB70_001262"
     CDS             complement(30485..31363)
                     /gene="dapA"
                     /locus_tag="IRB70_001262"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001311023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBC0631203.1"
                     /translation="MFTGSIVAIVTPMDEKGNVCRASLKKLIDYHVASGTSAIVSVGT
                     TGESATLNHDEHADVVMMTLELADGRIPVIAGTGANATAEAISLTQRFNDSGIVGCLT
                     VTPYYNRPSQEGLYQHFKAIAEHTDLPQILYNVPSRTGCDLLPETVGRLAKVKNIIGI
                     KEATGNLTRVNQIKELVSDDFVLLSGDDASALDFMQLGGHGVISVTANVAARDMAQMC
                     KLAAEGHFAEARVINQRLMPLHNKLFVEPNPIPVKWACKELGLVATDTLRLPMTPITD
                     SGRETVRAALKHAGLL"
     gene            31509..32081
                     /locus_tag="IRB70_001263"
     CDS             31509..32081
                     /locus_tag="IRB70_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     repressor"
                     /protein_id="HBC0631204.1"
                     /translation="MTLSSQHYLVITALGADRPGIVNTITRHVSSCGCNIEDSRLAML
                     GEEFTFIMLLSGSWNAITLIESTLPLKGAELDLLIVMKRTTARPRPPMPASVWVQVDV
                     ADSPHLIERFTALFDAHHMNIAELVSRTQPAENERAAQLHIQITAHSPASADAANIEQ
                     AFKALCTELNAQGSINVVNYSQHDEQDGVK"
     gene            32081..32551
                     /gene="bcp"
                     /locus_tag="IRB70_001264"
     CDS             32081..32551
                     /gene="bcp"
                     /locus_tag="IRB70_001264"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-dependent thiol peroxidase"
                     /protein_id="HBC0631205.1"
                     /translation="MNPLKAGDIAPKFSLPDQDGEQVNLTDFQGQRVLVYFYPKAMTP
                     GCTVQACGLRDNMDELKKAGVDVLGISTDKPEKLSRFAEKELLNFTLLSDEDHQVCEQ
                     FGVWGEKSFMGKTYDGIHRISFLIDADGKIEHVFDDFKTSNHHDVVLNWLKEHA"
     gene            32804..33421
                     /gene="hyfA"
                     /locus_tag="IRB70_001265"
     CDS             32804..33421
                     /gene="hyfA"
                     /locus_tag="IRB70_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311370.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfA"
                     /protein_id="HBC0631206.1"
                     /translation="MNRFVVAEPLWCTGCNTCLAACSDVHKTQGLQQHPRLALAKTST
                     LTAPVVCHHCEEAPCLQVCPVNAISQRDDAIQLNESLCIGCKLCAVVCPFGAISASGS
                     RPVNAPAQYVFQAEGSLKDGEENAPTQHALLRWEPGVQTVAVKCDLCDFLPEGPACVR
                     ACPNQALRLITDDSLQRQMKEKQRLAASWFANGGEDPLSLTQEQR"
     gene            33421..35439
                     /gene="hyfB"
                     /locus_tag="IRB70_001266"
     CDS             33421..35439
                     /gene="hyfB"
                     /locus_tag="IRB70_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit B"
                     /protein_id="HBC0631207.1"
                     /translation="MDALQLLTWSLILYLFASLASLFLLGLDRLAIKLSGITSLVGGV
                     IGIISGITQLHAGVTLAARFATPFEFADLTLRMDSLSAFMVLVISLLVVVCSLYSLTY
                     MREYEGKGAAAMGFFMNLFIASMVALLVMDNAFWFIVLFEMMSLSSWFLVIARQDKTS
                     INAGMLYFFIAHAGSVLIMIAFLLMGRESGSLDFASFRTLSLSPGLASAVFLLAFFGF
                     GAKAGMMPLHSWLPRAHPAAPSHASALMSGVMVKIGIFGILKVAMDLLAQTDLPLWWG
                     ILVMAIGAISALLGVLYALAEQDIKRLLAWSTVENVGIILLAVGVAMVGLSLHDPLLT
                     VVGLLGALFHLLNHALFKGLLFLGAGAIISRLHTHDMEKMGALAKRMPWTAAACLIGC
                     LAISAIPPLNGFISEWYTWQSLFSLSRVEAVALQLAGPIAMVMLAVTGGLAVMCFVKM
                     YGITFCGAPRSTHAEEAQDVPNTMIVAMLLLAALCVFIALSASWLAPKIMHIAHAFTN
                     TPPVTVASGIALVPGTFHTRVTPSLLLLLLLAMPLLPGLYWLWCRSRRAAFRRTGDAW
                     ACGYGWDNAMAPSGNGVMQPLRVVFCALFRLRQQLDPTLRLNKGLAHVTARAQSTEPF
                     WDERVIRPIVSATQRLAKEIQHLQSGDFRLYCLYVVAALVVLLIAIAV"
     gene            35450..36397
                     /gene="hyfC"
                     /locus_tag="IRB70_001267"
     CDS             35450..36397
                     /gene="hyfC"
                     /locus_tag="IRB70_001267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416978.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfC"
                     /protein_id="HBC0631208.1"
                     /translation="MRQTLCDGYLIIFALAQAVILLALTPLFTGISRQIRARMHSRRG
                     PGIWQDYRDIHKLFKRQEVAPTSSGLMFRLMPWVLISSMLVLAMALPLFITVSPFAGG
                     GDLITLIYLLALFRFFFALSGLDTGSPFAGIGASRELTLGILVEPMLILSLLVLALIA
                     DSTHIEMISKTLATGWNSPLTTVLALLACGFACFIEMGKIPFDVAEAEQELQEGPLTE
                     YSGAGLALAKLGLGLKQVVMASLFVALFLPFGRAQELSLTCLLTSLVVTLLKVLLIFV
                     LASIAENTLARGRFLLIHHVTWLGFSLAALAWVFWLTGL"
     gene            36414..37853
                     /gene="hyfD"
                     /locus_tag="IRB70_001268"
     CDS             36414..37853
                     /gene="hyfD"
                     /locus_tag="IRB70_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit HyfD"
                     /protein_id="HBC0631209.1"
                     /translation="MENLALTTLLLPFIGALVVSFSPQRRAAEWGVLFAALTTLCMLS
                     LISAFYQADKVAVTLTLVNVGDVALFGLVIDRVSTLILFVVVFLGLLVTIYSTGYLTD
                     KNREHLHNGTNRYYAFLLVFIGAMAGLVLSSTLLGQLLFFEITGGCSWALISYYQSDK
                     AQRSALKALLITHIGSLGLYLAAATLFLQTGTFALSAMSELHGDARYLVYGGILFAAW
                     GKSAQLPMQAWLPDAMEAPTPISAYLHAASMVKVGVYIFARAIIDGGNIPHVIGGVGM
                     VMALVTILYGFLMYLPQQDMKRLLAWSTITQLGWMFFGLSLSIFGSRLALEGSIAYIV
                     NHAFAKSLFFLVAGALSYSCGTRLLPRLRGVLHTLPLPGVGFCVAALAITGVPPFNGF
                     FSKFPLFAAGFSLSVEYWILLPAMILLMFESVASFAWFIRWFGRVVPGKPSEAVADAA
                     PLPGSMRLVLIVLIVMSLISSVIAATWLQ"
     gene            37865..38515
                     /gene="hyfE"
                     /locus_tag="IRB70_001269"
     CDS             37865..38515
                     /gene="hyfE"
                     /locus_tag="IRB70_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 membrane subunit"
                     /protein_id="HBC0631210.1"
                     /translation="MTGSMIVNNLAGLMMLTSLFVISVKSYRLSCGFYACQSLVLVSI
                     FATLSCLFVAEQLLIWSASAFITKVLLVPLIMIYAARNIPQNIPEKALFGPAMMALLA
                     ALIVLLCAFVVQPVKLPMATGLKPALAVALGHFLLGLLCIVSQRNILRQIFGYCLMEN
                     GSHLVLALLAWRAPELVEIGIATDAIFAVIVMVLLARKIWRTHGTLDVNNLTALKG"
     gene            38520..40100
                     /gene="hyfF"
                     /locus_tag="IRB70_001270"
     CDS             38520..40100
                     /gene="hyfF"
                     /locus_tag="IRB70_001270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit F"
                     /protein_id="HBC0631211.1"
                     /translation="MSYSVMFALLLLTPLLFSLLCFACRKWGHSATRTVTVLHSLGIT
                     LLLILTLWVVQTAADAGEIFAAGLWLHIDGLGGLFLAILGVIGFLTGVYSIGYMRHEV
                     AHGELSPVTLCDYYGFFHLFLFTMLLVVTSNNLIVMWAAIEATTLSSAFLVGIYGQRS
                     SLEAAWKYIIICTVGVAFGLFGTVLVYANAASVMPQAEMAIFWSEVLKQSSLLDPTLM
                     LLAFVFVLIGFGTKTGLFPMHAWLPDAHSEAPSPVSALLSAVLLNCALLVLIRYYIII
                     CQAIGSDFPNRLLLIFGMLSVAVAAFFILVQRDIKRLLAYSSVENMGLVAVALGIGGP
                     LGIFAALLHTLNHSLAKTLLFCGSGNVLLKYGTRDLNVVCGMLKIMPFTAVLFGGGAL
                     ALAGMPPFNIFLSEFMTVTAGLARNHLLIIVLLLLLLTLVLAGLVRMAARVLMAKPPQ
                     AVNRGELGWLTTSPMVILLVMMLAMGTHIPQPVIRILAGASTIVLSGTHDLPAQRSTW
                     HDFLPSGTASVSEKHSER"
     gene            40090..41805
                     /gene="hyfG"
                     /locus_tag="IRB70_001271"
     CDS             40090..41805
                     /gene="hyfG"
                     /locus_tag="IRB70_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfG"
                     /protein_id="HBC0631212.1"
                     /translation="MNVNSSSNRGEAILAALKTQFPGAVLDEERQTPEQVTITVKINL
                     LPDVVHYLYYQHDGWLPVLFGNDERTLNGHYAVYYALSMEGAEKCWIVVKALVDADSR
                     EFPSVTPRVPAAVWGEREIRDMYGLIPVGQPDQRRLVLPDDWPEDMHPLRKDAMDYRL
                     RPEPTTDTETYPFINEGNSDARVIPVGPLHITSDEPGHFRLFVDGEQIVDADYRLFYV
                     HRGMEKLAETRMGYNEVTFLSDRVCGICGFAHSVAYTNSVENALGIEVPQRAHTIRSI
                     LLEVERLHSHLLNLGLSCHFVGFDTGFMQFFRVREKSMTMAELLTGSRKTYGLNLIGG
                     VRRDILKEQRLQTLKLVREMRADVSELVEMLLATPNMEQRTQGIGILDRQIARDYSPV
                     GPLIRGSGFARDLRFDHPYADYGNIPKTLFTFTGGDVFSRVMVRVKETFDSLAMLEFA
                     LDNMPDTPLLTEGFSYKPHAFALGFVEAPRGEDVHWSMLGDNQKLFRWRCRAATYANW
                     PVLRYMLRGNTVSDAPLIIGSLDPCYSCTDRVTLVDVRKRQSKTVPYKEIERYGIDRN
                     RSPLK"
     gene            41815..42360
                     /gene="hyfH"
                     /locus_tag="IRB70_001272"
     CDS             41815..42360
                     /gene="hyfH"
                     /locus_tag="IRB70_001272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 subunit H"
                     /protein_id="HBC0631213.1"
                     /translation="MLKLLKTIMRAGTATVKYPFAPLEVSPGFRGKPDLMPSQCIACG
                     ACACACPANALTIQTDDQQNTRTWQLYLGRCIYCGRCEEVCPTRAIQLTNNFELTVTN
                     KADLYTRATFHLQRCSRCERPFAPQKTVALAAELLAQQQNAPQNREMLWAQASICPEC
                     KQRATLINDDTDVPLVAKEQL"
     gene            42357..43115
                     /gene="hyfI"
                     /locus_tag="IRB70_001273"
     CDS             42357..43115
                     /gene="hyfI"
                     /locus_tag="IRB70_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000075566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 4 catalytic subunit HyfI"
                     /protein_id="HBC0631214.1"
                     /translation="MSPVLTQHVSQPITLDEQTQKMKQHLLQDIRRSAYVYRVDCGGC
                     NACEIEIFAAITPVFDAERFGIKVVSSPRHADILLFTGAVTRAMRMPALRAYESAPDH
                     KICVSYGACGVGGGIFHDLYSVWGGSDTIVPIDVWIPGCPPTPAATIHGFAVALGLLQ
                     QKIHAVDYRDPTGVTMQPLWPQIPPSQRIAIEREARRLAGYRQGREICDRLLRHLSDD
                     PTGNRVNTWLREADDPRLNSIVQQLFRVLRGLHG"
     gene            43108..43521
                     /locus_tag="IRB70_001274"
     CDS             43108..43521
                     /locus_tag="IRB70_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416985.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate hydrogenlyase maturation HycH family
                     protein"
                     /protein_id="HBC0631215.1"
                     /translation="MAEECREIVFWTLRKKFIASSDEMPEHSSQVMYYSLAIGHHVGV
                     IDCLNVAFRCPQTEYEDWLAQVEEEQARRKMLGVMTFGEIVIDASHTALLTRAFAPLA
                     DDATSAWQARSIQFIHLLDEIVQEPVIYLMARKIA"
     gene            43551..45563
                     /gene="hyfR"
                     /locus_tag="IRB70_001275"
     CDS             43551..45563
                     /gene="hyfR"
                     /locus_tag="IRB70_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HyfR"
                     /protein_id="HBC0631216.1"
                     /translation="MAMSDEAMFAPPQGITIEAVNGMLAERLAQKHGKASLLRAFIPL
                     PPPFSPVQLIELHVLKSNFYYRYHDDGSDVTATTEYQGEMVDYSRHAVLLGSSGMAEL
                     RFIRTHGSRFTPQDCTLFNWLAHIITPVLQSWLNDEEQQVALRLLEKDRDHHRVLVDI
                     TNAVLSHLDLDDLIADVAREIHHFFGLASVSMVLGDHRKNEKFSLWCSDLSASHCACL
                     PRCMPGESVLLTQTLQTRQPTLTHCADDLFLWQRDPLLHLLASNGCESALLIPLTFGN
                     HTPGALLLAHTSSTLFSEENCQLLQHIADRIAIAVGNADAWRSMTDLQESLQQENHQL
                     SEQLLSNLGVGDIIYQSQAMEDLLQQVDIVAKSDSTVLICGETGTGKEVIARAIHQLS
                     PRRDKPLVKINCAAIPASLLESELFGHDKGAFTGAINTHRGRFEIADGGTLFLDEIGD
                     LPLELQPKLLRVLQEREIERLGGSRTIPVNVRVIAATNRDLWQMVEDRQFRSDLFYRL
                     NVFPLELPPLRDRPEDIPLLAKHFTQKMARHMNRAIDAIPTEALRQLMSWDWPGNVRE
                     LENVIERAVLLTRGNSLNLHLNVRQSRLLPTLNEDSALRSSMAQLLHPTTPENDEEER
                     QRIVQVLRETNGIVAGPRGAATRLGMKRTTLLSRMQRLGISVREVL"
     gene            45585..46433
                     /locus_tag="IRB70_001276"
     CDS             45585..46433
                     /locus_tag="IRB70_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter"
                     /protein_id="HBC0631217.1"
                     /translation="MRNKLSFDLQLSARKAAIAERIAAHKITRSKVSVFLMAMSAGVF
                     MAIGFTFYLTVIADAPSSQALTHLVGGLCFTLGFILLAVCGTSLFTSSVMTVMAKSRG
                     VISWRTWLINALLVACGNLAGIACFSLLIWFSGLVMSENAMWGVAVLHCAEGKMHHTF
                     TESVSLGIMCNVMVCLALWMSYCGRSLCDKIVAMILPITLFVASGFEHCIANLFVIPF
                     AIAIRHFAPTSFWQLAHSSADHFPALTVSHFITANLLPVMLGNIIGGAVLVSICYRAI
                     YLRQEP"
     gene            complement(46470..47531)
                     /locus_tag="IRB70_001277"
     CDS             complement(46470..47531)
                     /locus_tag="IRB70_001277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBC0631218.1"
                     /translation="MLEMLMQWYRRRFSDPEAIALLVILVAGFGIIFFFSGLLAPLLV
                     AIVLAYLLEWPTVRLQSIGCSRRWATSIVLVVFVGILLLMAFVVLPIAWQQGIYLIRD
                     MPGMLNKLSDFAATLPRRYPALMDAGIIDAMAENMRSRMLTMGDSVVKISLASLVGLL
                     TIAVYLVLVPLMVFFLLKDKEQMLNAVRRVLPRNRGLAGQVWKEMNQQITNYIRGKVL
                     EMIVVGIATWLGFLLFGLNYSLLLAVLVGFSVLIPYIGAFVVTIPVIGVALFQFGAGT
                     EFWSCFAVYLIIQALDGNLLVPVLFSEAVNLHPLVIILSVVIFGGLWGFWGVFFAIPL
                     ATLIKAVIHAWPDGQIAQE"
     gene            47744..49207
                     /gene="bepA"
                     /locus_tag="IRB70_001278"
     CDS             47744..49207
                     /gene="bepA"
                     /locus_tag="IRB70_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-barrel assembly-enhancing protease"
                     /protein_id="HBC0631219.1"
                     /translation="MFRQLKKNLVATLIAAMTIGQVAPAFADSADTLPDMGTSAGSTL
                     SIGQEMQMGDYYVRQLRGSAPLINDPLLTQYINSLGMRLVSHANSVKTPFHFFLINND
                     EINAFAFFGGNVVLHSALFRYSDNESQLASVMAHEISHVTQRHLARAMEDQQRSAPLT
                     WVGALGSILLAMASPQAGMAALTGTLAGTRQGMISFTQQNEQEADRIGIQVLQRSGFD
                     PQAMPTFLEKLLDQARYSSRPPEILLTHPLPESRLADARNRANQMRPMVVQSSEDFYL
                     AKARTLGMYNSGRNQLTSDLLDEWAKGNVRQQRAAQYGRALQAMEANKYDEARKTLQP
                     LLAAEPGNAWYLDLATDIDLGQNKANEAINRLKNARDLRTNPVLQLNLANAYLQGGQP
                     QEAANILNRYTFNNKDDSNGWDLLAQAEAALNNRDQELAARAEGYALAGRLDQAISLL
                     SSASSQVKLGSLQQARYDARIDQLRQLQERFKPYTKM"
     gene            49228..49587
                     /gene="arsC"
                     /locus_tag="IRB70_001279"
     CDS             49228..49587
                     /gene="arsC"
                     /locus_tag="IRB70_001279"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311384.1"
                     /note="This arsenate reductase requires both glutathione
                     and glutaredoxin to convert arsenate to arsenite, after
                     which the efflux transporter formed by ArsA and ArsB can
                     extrude the arsenite from the cell, providing resistance;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase (glutaredoxin)"
                     /protein_id="HBC0631220.1"
                     /translation="MTKQVKIYHNPRCSKSRETLSLLKENGVEPEVVLYLETPADAAT
                     LRDLLKMLGMNSARELMRQKEDLYKELNLADSSLSEGALIQAMVDNPKLMERPIVVAN
                     GKARIGRPPELVLEIVG"
     gene            complement(49693..50439)
                     /gene="hda"
                     /locus_tag="IRB70_001280"
     CDS             complement(49693..50439)
                     /gene="hda"
                     /locus_tag="IRB70_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA inactivator Hda"
                     /protein_id="HBC0631221.1"
                     /translation="MVNFSRFCEILVEVSLNTPAQLSLPLYLPDDETFASFWPGDNSS
                     LLAALQNVLRQEHSGYIYLWAREGAGRSHLLHAACAELSQRGDAVGYVPLDKRTWFVP
                     EVLDGMEHLSLVCIDNIECIAGDELWEMAIFDLYNRILESGKTRLLITGDRPPRQLNL
                     GLPDLASRLDWGQIYKLQPLSDEDKLQALQLRARLRGFELPEDVGRFLLKRLDREMRT
                     LFMTLDQLDRASITAQRKLTIPFVKEILKL"
     gene            complement(50489..51778)
                     /gene="uraA"
                     /locus_tag="IRB70_001281"
     CDS             complement(50489..51778)
                     /gene="uraA"
                     /locus_tag="IRB70_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBC0631222.1"
                     /translation="MTRRAIGVSERPPLLQTIPLSLQHLFAMFGATVLVPVLFHINPA
                     TVLLFNGIGTLLYLFICKGKIPAYLGSSFAFISPVLLLLPLGYEVALGGFIMCGVLFC
                     LVSFIVKKAGTGWLDVLFPPAAMGAIVAVIGLELAGVAAGMAGLLPAEGQTPDSKTII
                     ISITTLAVTVLGSVLFRGFLAIIPILIGVLVGYALSFAMGIVDTTPIINAHWFALPTL
                     YTPRFEWFAILTILPAALVVIAEHVGHLVVTANIVKKDLLRDPGLHRSMFANGLSTVI
                     SGFFGSTPNTTYGENIGVMAITRVYSTWVIGGAAIFAILLSCVGKLAAAIQMIPLPVM
                     GGVSLLLYGVIGASGIRVLIESKVDYNKAQNLILTSVILIIGVSGAKVNIGAAELKGM
                     ALATIVGIGLSLIFKLISMLRPEEVVLDAEDADITDK"
     gene            complement(51864..52490)
                     /gene="upp"
                     /locus_tag="IRB70_001282"
     CDS             complement(51864..52490)
                     /gene="upp"
                     /locus_tag="IRB70_001282"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBC0631223.1"
                     /translation="MKIVEVKHPLVKHKLGLMREQDISTKRFRELASEVGSLLTYEAT
                     ADLETEKVTIEGWNGPVEIDQIKGKKITVVPILRAGLGMMDGVLENVPSARISVVGMY
                     RNEETLEPVPYFQKLVSNIDERMALIVDPMLATGGSVIATIDLLKKAGCSSIKVLVLV
                     AAPEGIAALEKAHPDVELYTASIDQGLNEHGYIIPGLGDAGDKIFGTK"
     gene            52814..53851
                     /gene="purM"
                     /locus_tag="IRB70_001283"
     CDS             52814..53851
                     /gene="purM"
                     /locus_tag="IRB70_001283"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBC0631224.1"
                     /translation="MTDKTSLSYKDAGVDIDAGNALVGRIKGVVKKTRRPEVMGGLGG
                     FGALCALPQKYREPVLVSGTDGVGTKLRLAMDLKRHDTIGIDLVAMCVNDLVVQGAEP
                     LFFLDYYATGKLDVDTASAVISGIAEGCLQSGCSLVGGETAEMPGMYHGEDYDVAGFC
                     VGVVEKSEIIDGSKVSDGDVLIALGSSGPHSNGYSLVRKILEVSGCDPQTTELDGKPL
                     ADHLLAPTRIYVKSVLELIEKVDVHAIAHLTGGGFWENIPRVLPDNTQAVIDESSWQW
                     PEVFNWLQTAGNVERHEMYRTFNCGVGMIIALPAPEVDKALALLNANGENAWKIGIIK
                     ASDSEQRVVIE"
     gene            53851..54489
                     /gene="purN"
                     /locus_tag="IRB70_001284"
     CDS             53851..54489
                     /gene="purN"
                     /locus_tag="IRB70_001284"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBC0631225.1"
                     /translation="MNIVVLISGSGSNLQAIIDACKTNKIKGTVRAVFSNKADAFGLE
                     RARQAGIATHTLIASAFDSREAYDRELIHEIDMYAPDVVVLAGFMRILSPAFVSHYAG
                     RLLNIHPSLLPKYPGLHTHRQALENGDEEHGTSVHFVTDELDGGPVILQAKVPVFAGD
                     TEDDITARVQTQEHAIYPLVISWFADGRLKMHENAAWLDGQRLPPQGYAADE"
     gene            54661..56727
                     /gene="ppk1"
                     /locus_tag="IRB70_001285"
     CDS             54661..56727
                     /gene="ppk1"
                     /locus_tag="IRB70_001285"
                     /EC_number="2.7.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphosphate kinase 1"
                     /protein_id="HBC0631226.1"
                     /translation="MGQEKLYIEKELSWLSFNERVLQEAADKSNPLIERMRFLGIYSN
                     NLDEFYKVRFAELKRRIIISEEQGSNSHSRHLLGKIQSRVLKADQEFDGLYNELLLEM
                     ARNQIFLINERQLSVNQQNWLRHYFKQYLRQHITPILINPDTDLVQFLKDDYTYLAVE
                     IIRGDTIRYALLEIPSDKVPRFVNLPPEAPRRRKPMILLDNILRYCLDDIFKGFFDYD
                     ALNAYSMKMTRDAEYDLVHEMEASLMELMSSSLKQRLTAEPVRFVYQRDMPNALVEVL
                     REKLTISRYDSIVPGGRYHNFKDFINFPNVGKANLVNKPLPRLRHIWFDKAQFRNGFD
                     AIRERDVLLYYPYHTFEHVLELLRQASFDPSVLAIKINIYRVAKDSRIIDSMIHAAHN
                     GKKVTVVVELQARFDEEANIHWAKRLTEAGVHVIFSAPGLKIHAKLFLISRKENGEVV
                     RYAHIGTGNFNEKTARLYTDYSLLTADARITNEVRRVFNFIENPYRPVTFDYLMVSPQ
                     NSRRLLYEMVDREIANAQQGLPSGITLKLNNLVDKGLVDRLYAASSSGVPVNLLVRGM
                     CSLIPNLEGISDNIRAISIVDRYLEHDRVYIFENGGDKKVYLSSADWMTRNIDYRIEV
                     ATPLLDPRLKQRVLDIIDILFSDTVKARYIDKELSNRYVPRGNRRKVRAQLAIYDYIK
                     SLEQPE"
     gene            56732..58273
                     /gene="ppx"
                     /locus_tag="IRB70_001286"
     CDS             56732..58273
                     /gene="ppx"
                     /locus_tag="IRB70_001286"
                     /EC_number="3.6.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exopolyphosphatase"
                     /protein_id="HBC0631227.1"
                     /translation="MPIHDKSPRPQEFAAVDLGSNSFHMVIARVVDGAMQIIGRLKQR
                     VHLADGLGPDNMLSEEAMTRGLNCLSLFAERLQGFSPASVCIVGTHTLRQALNATDFL
                     KRAEKVIPYPIEIISGNEEARLIFMGVEHTQPEKGRKLVIDIGGGSTELVIGENFEPI
                     LVESRRMGCVSFAQLYFPGGVINKENFQRARMAAAQKLETLTWQFRIQGWNVAMGASG
                     TIKAAHEVLMEMGEKDGIITPERLEKLVKEVLRHRNFASLSLPGLSEERKTVFVPGLA
                     ILCGVFDALAIRELRLSDGALREGVLYEMEGRFRHQDVRSRTASSLANQYHIDSEQAR
                     RVLDTTMQMYEQWREQQPKLAHPQLEALLRWAAMLHEVGLNINHSGLHRHSAYILQNS
                     DLPGFNQEQQLMMATLVRYHRKAIKLDDLPRFTLFKKKQFLPLIQLLRLGVLLNNQRQ
                     ATTTPPTLTLITDDSHWTLRFPHDWFSQNALVLLDLEKEQEYWEGVAGWRLKIEEEST
                     PEIAA"
     gene            complement(58312..60555)
                     /gene="pdeF"
                     /locus_tag="IRB70_001287"
     CDS             complement(58312..60555)
                     /gene="pdeF"
                     /locus_tag="IRB70_001287"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase
                     PdeF"
                     /protein_id="HBC0631228.1"
                     /translation="MKLNATYIKIRDKWWGLPLFLPSLILPIFAHINTFAHISSGEVF
                     LFYLPLALMISMMMFFSWAALPGIALGIFVRKYAELGFYETLSLTANFIIIIILCWGG
                     YRVFTPRRNNVSHGDTRLISQRIFWQIVFPATLFLILFQFAAFVGLLASRENLVGVMP
                     FNLGTLINYQALLVGNLIGVPLCYFIIRVVRNPFYLRSYYSQLKQQVDVKVTKKEFAL
                     WLLALGALLLLLCMPLNEKSTIFSTNYTLSLLLPLMMWGAMRYGYKLISLLWAVVLMI
                     SIHSYQNYIPIYPGYTTQLTITSSSYLVFSFIVNYMAVLATRQRAVVRRIQRLAYVDP
                     VVHLPNVRALNRALRDAPWSALCYLRIPGMEMLVKNYGIMLRIQYKQKLSHWLSPLLE
                     PGEDVYQLSGNDLALRLNTESHQERITALDSHLKQFRFFWDGMPMQPQIGVSYCYVRS
                     PVNHIYLLLGELNTVAELSIVTNAPENMQRRGAMYLQRELKDKVAMMNRLQQALEHNH
                     FFLMAQPITGMRGDVYHEILLRMKGENDELISPDSFLPVAHEFGLSSSIDMWVIEHTL
                     QFMAENRAKMPAHRFAINLSPTSVCQARFPVEVSQLLAKYQIEAWQLIFEVTESNALT
                     NVKQAQITLQHLQELGCQIAIDDFGTGYASYARLKNVNADLLKIDGSFIRNIVSNSLD
                     YQIVASICHLARMKKMRVVAEYVENEEIREAVFSLGIDYMQGYLIGKPQPLIDTLNEI
                     EPIRESA"
     gene            complement(60737..60889)
                     /locus_tag="IRB70_001288"
     CDS             complement(60737..60889)
                     /locus_tag="IRB70_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631229.1"
                     /translation="MSHAVDGTYIKAQQDKMVNSSLCKKASVDTYFNVMEVNLIIYND
                     DVIMMN"
     gene            60907..61098
                     /locus_tag="IRB70_001289"
     CDS             60907..61098
                     /locus_tag="IRB70_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2633 family protein"
                     /protein_id="HBC0631230.1"
                     /translation="MSQATSMRKRHRFNSRMTRIVLLISFIFFFGRFIYSSVGAWQHH
                     QSKKEAQQSTLSVESPVQR"
BASE COUNT        14327 a        16208 c        15790 g        14872 t
ORIGIN      
        1 atgcacggtc cgttcttaac gaaaatgctg gtatcaatgg cattcgccat ctggttcatg
       61 ttctcgatat tgcgcgagtg cattgccgcc gtgtggtggc aaccgccttc cagtttcacc
      121 gccagcgcaa tggcatccgc cacgttggcg acgcgcacga cgggcagcac cggcatcatc
      181 agttcagtca cagcaaacgg atgttctgcg gtggtttcta caaacagcag tcgcgtttgt
      241 tccggaactt taaggccgat tgccgccgcg attttcgccg catcgcgacc aacccagtca
      301 cggctgacga tgccttttcc gcgctcgtcg atatttttca gcaacaccgg ttgcagctgc
      361 tgcgcctgct ctgcggtcag tttcaccgcg tgctggcctt ccatcagacg catcagttca
      421 tcggctacgc tatccacaac aatcagtacc ttttcgtcgg cacaaatgat gttgttatcg
      481 aaagacgcgc ctttgacgat ggactgagca gcacgggcga ggtcggcggt ttcatccacc
      541 actaccggcg ggttgccagc gcctgcggca atcagacgtt tattggtgtg tttacgcgcc
      601 gcttctacta ccgcttcgcc gccggtcacc accagcaggc cgatgcccgg aaacttgaac
      661 aaacgttgag cggtttcaat atccggattt gccacagtaa ccagtaagtt ttccggcccg
      721 cctgcggcaa caatcgcctg gttgagcagc gtgatcgccc gctgggagac ttttttcgcc
      781 gccggatgcg gggcaaaaat gacgctgttg cccgcggcaa tcaggctgat ggcgttatta
      841 atgacggttg ccgccgggtt ggtggacgga gttaccgaag ccaccacgcc ccagggcgcg
      901 ttttcaatta aagtcaggcc gttgtcgcca gtcagcactt gcggagagag gcactcaacg
      961 cctggtgtgc cgcgcgcctg agcgacgttt ttggcaaatt tatcttcaac gcgccccatg
     1021 ccggtttcac tgacggcaag ttccgctaaa tctctggcgt gtttttcgcc tgcttcacga
     1081 atggcagcaa tggctaactg gcgcattgcc acgcttttta acccttgctg ggcgactttg
     1141 gctgccgcaa cggcgtcatc cagggacgcg aaaacgccca tctcatgaac ggcggcgggc
     1201 ggcgtgtcac tgctttgcat tttcagcagt accgctttca ccacctgttc aatatcctgt
     1261 tgattcatga tgttctgcct tatttgtgga aaatgacctg accgccagac accacctcat
     1321 cgacaatgcc aatcacgcac agatcgaccg gtgacgtttc gcttttatgc gcctggcggg
     1381 cggaactgcc actcaccagt aacacccact ccccggttcc cgcgccaata ttgtcgatgg
     1441 cgacggcgca ttgcccgtca ggattacctt gtggatcaat catttccacc atcagcaatt
     1501 tgtcatgcgc cagtccgtga tggcgtacgg tacaaacaat ttgtccagtg acgactgcca
     1561 gtttcatacc cgcctccgtg gcgtatttca ggtaaaagct ccccctaccc tccgcagaag
     1621 gtaaaatgaa aaaggagaga gcgtgacgcc cgaatcgacg tcacacaggg tgattacagg
     1681 ttgctgctat cgcctttcag gccgatcggg aagacttctt ccaggtcgcc gtgcggacgc
     1741 gggataacgt gtacagatac cagctcgccg atacgctgtg ccgctgcagc acctgcgtcg
     1801 gtcgcggctt tacaggctgc aacatcacca cgaaccatgg cagtacacag gccgccgcca
     1861 atctgcttaa caccaaccag cttgacgcgc gcagctttca ccatcgcgtc agaagcctca
     1921 atcagtgcaa ccaggccccg ggtttcgatc attcctaatg cttccattgt gctttcctct
     1981 ttatcagggt ccagaacggg accgttcatt caaccagtgt ttgtaaactg ctttcgcggt
     2041 tcacttctgt ctgacgcggc acagctgcca ccagcgccag ttcgataatt tcctgcacgc
     2101 tacaaccacg agagagatcg tgcatcggcg cggcaagtcc ttgtatcaat ggcccgacgg
     2161 cacgatatcc gccaagtcgt tgtgcgattt tgtagccaat atttcctgcc tccagcgacg
     2221 gaaaaaccat cacattggct ttgccctgta acgggctggc tggcgctttt tgcgccgcca
     2281 cttccggcac gaaggcggcg tcaaactgca actcgccatc gacaaccagc tttggtgcgc
     2341 actcacggac gatttctgtc gcctgctgga cgttggcaac gcaggggtga cgggcactac
     2401 cgttgctgga aaacgacagc atcgccacgc gcggttcttc tccggtgatg gcgcgccagg
     2461 tttcggcgct ggcaagcgcg atatccgcca gttgtgccgc cgtcggctgc ggcaccacgc
     2521 tgcaatcggc aaagcccaac gccggaccgc tgtactgtgg cagcatcagg aaaatggatg
     2581 agagcgtttt acagcctggc tgcaagccga taatgcgtaa tccggcacgc agcacattcg
     2641 ccgtggaaga gaggttgccc gcgatacaga catccgcttt gccggcgctg accattgcgg
     2701 cggcgaacat cagcggatcg gtaagttttt ccagcgcatc cggcggcgtt ttttcgcccg
     2761 cgcgggccag ccagcgatga gcaaattctt cccgcattgc gaggttgcca tgcggatcaa
     2821 tcacctgtag cccgtccatc gccacgccat gactgagcgc aaactgacga agttcaaacg
     2881 gattggcgac cagaatgggc gttgccagac cttgttgatg taaatattgc gcagctttca
     2941 gcacacgttg atctaacgca tccggaaaaa ctactctggc gggcgctcgc aacgccagtt
     3001 cacgacaacg tttaataatc attgcgtttc ccccagtcgt tgttggatct gcttcaccgt
     3061 tagcggttgt ttcgctacgc tcaggatcat catcacgtag accgtgctcg aaaggcggtt
     3121 cagcgcctgc aaaatgtccg ggcgtaatac ttcaaagctg cgggtgataa agacctgcgc
     3181 cgctacggtt tcggtttccc gcactttggt gcgtagcaga tttagcaacg ccgcatcgcg
     3241 cccgtggctg gcttccggca ccagatgatc gtggtcgaga taacgcagcg gctggtgaga
     3301 aagccgatgc agatcttcgt cagaaagccc gacaatcgcc tggcaggcca gcggttcccc
     3361 cagcgcatcg gcacgcataa tgttgccaag acgcgaacgg atatccgcca gccacggctg
     3421 ccacggttcc gccagttcaa tttgcagcca cactgccagc gcaatggtgc tgtcgagaac
     3481 cgcgcgaaaa gccaggcgcg gatcgctttt ggcaaccatt ttttccgccg acaggtgagt
     3541 cagcgtatcc ggcttttttg ccaccggctg gcggcacagt tcgcagcacg cctgcggatg
     3601 ttcatcgcta ctggtaagcc cgtgaacggg ctgcggctgc tgctgttcat cgtcaacaaa
     3661 caggcggccc tgctcgtcaa taaacttgat gcgcagatgg cggctttcca gtaactcccg
     3721 ggcagagggc gtcaggcgac tgtccgcagg gagatggatc tctgcgcctt cgctgagcgt
     3781 atggttcgct cttagccatg cttcggtgat gaaatctttc atagggattg ccagttagcc
     3841 ggccaggcga catacaggaa tttcacgctg gatgtcgtac caaattcgat actggagcct
     3901 ttcgggataa acatcacatc gcccgctttg gcgatcatag tttcgccttc gtggcgaaca
     3961 tgcagctccc cttccagcac catgtcgatt tcgtcgtagt tcagggtcca cggaaagaag
     4021 gcgttctccc actgcataaa accagcggcc atactgctgc cgtcgtctcc ggtcacgaga
     4081 tcagtcaagc ctacgcagtg cggttccgcg ccatcgaaac gaccaaactt gacgctgctg
     4141 ccatcaatca ctttgatgcc gcctttgccg gtcaccgatt tgaaactcgg ctgcattgca
     4201 ccctgctcca gtgactgttt ttccttcatc actttttcca tcagctgcgc gaccaggctt
     4261 tcggtaaact ggccttccgg tagctgggcg atgatggttt cgcggatgcg ctggctttcg
     4321 gttttatcgg ctggcacgct ggcgggaacg gacgtcgtta ccgcagtcga ttcatcacat
     4381 tcggtgatgg taaaacccaa cagatcagcc acttcacgag cttccggggt aataatgctg
     4441 gcgcgcagaa ccacggacat tgccagttcg ccgcgcgcgt gtgcttcacg aatatcattc
     4501 gctgtgatga gttttttcac ctgcttcctc ctgtttggtg agagatgcca gataatccac
     4561 cagttgctgc acgctttgcg ggtcgtggct gtttagctcg aaaatcggct cttcgaagcc
     4621 cgtctcaagc aataactttc gcgttgcggc gacgtcagca tctggcatgt ccgttttact
     4681 gatgacggcg atttgccgtt tgctgacgcc aatatccagc aacccggcag gcaaccgact
     4741 ttccgggtca ttcgcgccgt ggacatagat cagcatgtcc acatcctgta gcgtggtaat
     4801 taaggcgtga taccagcggg gatggctaaa atattcaccc ggcgtatcaa tatcgccctt
     4861 atcattaaat tccacggcct gtgtttttct ggcgagggta taattcccct gcaacgcatt
     4921 aaataacgtt gtttttcctg ccccgacggt acccacaaac gcaattcgtt tcatgaatgc
     4981 ctcgtattaa cttttggtca tttcacaaag cgtataattt aataagcgtc ctaaaccact
     5041 gacggtttgt gataacgctt cttctactgc gcccaccgag ccataaatca ccagcgcgcc
     5101 gctaaaacgg tcgagaaaac cgatatgcac atcggcggct ttcaacgcta aatcaccggc
     5161 gatcatcgcc gtttctccgg gagttagcgt cataatgccg attgcgcccg catccggaac
     5221 gccgattttc ttcgccagtt cctcgccggg atgcgcgatg agatgcgcca gtgtgacctg
     5281 tttaccgggc acaaattcct gaatgatgcg ttctttatcc atgagtcgcc gcctgtgaaa
     5341 aactttcgtg tatcgtgaca atttttcgtc agagtaaata acaaaattcg gcaagcgcgt
     5401 ttaaaaggtg aggtagatca ctaagaatgg agagatattt tatgttaaga aaaaaaacat
     5461 acattgtatg aatataaacg ggaaccaata agttttgttt atcatatgta ctacaacatc
     5521 ttttaataat ccctcgaatc acccgacgtt gtatttttaa taattagcag aatacatatt
     5581 taatgtactg ttgtattctg aaaaatatta ttatcttcac cccatttaaa atacatctta
     5641 cgcgatgatt ttattcagga aataaataaa atggatggat ccctggaatg aaaattcact
     5701 accttgtcac caccctcgaa gcgggaggcg ctgaatttgc gattcctgat attgtgacta
     5761 ctctgcaaga ccttggtcat gaggtgaaaa tttatgtctg tgaaccccgc gatatgggag
     5821 cagcgcctcg tctggaagcc gctggattat cctggtgttt attatcaaat cggcggcgtt
     5881 ctgaacccat gcttgtagct gcttatctgg caaaaatcat tcacgacaaa cccgatctca
     5941 tctggacttc gttaagttgg gggactcgta ttgggcaatg ggtcggccgg cttatgggca
     6001 ttcctgttat cagttttaaa catagcgcca gcgtaaaacc agcgacctgg cgtatgcgca
     6061 acatgtctcg tttatggata ggagattctg aaaccgtagc tcaatacctg catgaaacca
     6121 tgttgatccc gaagcaacaa gtgctgtgct ggcccttttt tcaggcgaat ccgcaagctg
     6181 cccaagcgca aaactgggac gggaaatcag ttttacaatt aggctctgtt ggacgcctgc
     6241 atgaagttaa aaattacgct ggattaatta cagcactcgc ttcgtttgta gataaaaacc
     6301 cgcaattgcg ctcgcgaatc cgattaacca ttctcggtga agggcctgaa caggaagcat
     6361 tgcaaaaaac cataacgcaa cacgcgttgg aggatgtggt ttgtttagcg ggtttttctg
     6421 cggatgtcga aaattttctt gccggattac atgtctacat ccagacctcc cgctacgaag
     6481 ggatgtgcct cgctgcacac gaagccatga atgcagggct tgcaatcatc acgactcctg
     6541 taggcgaact taaagaatcg gtaatagatg gtcatactgg atatacgctt aatggcgagc
     6601 taacgccagc gctggagggt gtgcttaacc gtattttcag tgaacccgaa gaattagaac
     6661 gctatgggca aaatgtgcgg cagtatgtat tagcgaagtt cagccatgaa aattttgtcc
     6721 agtctgcaat caacatcgtc aatagactta ttcactgaac aaggcagaaa aatgaattgc
     6781 tataccaccg atctttggca gataggcatt gttcaggccc ccatacagca cattgttgct
     6841 tctggcagtt tggatggctt caggattaaa tggattaccc cggataaatc actcactttt
     6901 cttgccgatc ctttcggtct gtggaaaaaa ggggttctct atcttttcgc ggaatcctac
     6961 gattatcgga ctcgtcgtgg cgatattatc gcttataagc tcaatgctga cctggacgtc
     7021 attgagcaac gaactgtgct acaagaaccc tggcatcttt cttatccttt tgtgtttgaa
     7081 gccgataacg aaatctggat gttacctgaa ggatataaat caggtacgct aacgttgtac
     7141 cgcgctatag agtttccctg gcgatgggaa aaggtgccag atttttcatt cccttgcgct
     7201 gccattgatg ccaccccctt ttacgcacaa ggaaaatggt ggatgtttta tactccccca
     7261 ctaccaaagg cagccaggac ggatacgtta atgctcgctc atgcccccca ttttatgggg
     7321 ccatgggaaa acgtcctgca aactgccgcg cacaggaata aaagcggcgc gcgtatgggc
     7381 ggaacaccat ttgatcatga tgggcaaatt ttcttaccaa cacaagattg cagccgaacc
     7441 tacggtggcg cattgcagat gctgacacta gacccacaac gtttattaac tccagaattt
     7501 gctgcctctg tgcgcctgga agtgcctgca agtgccgcgc cttttattgc tggcatgcat
     7561 acgctttctg gcgttggcga cgtaacattc attgatgcca agcgacacct taaaggttcg
     7621 cctcagcgat tatgggtgga tttgcagcgg cggatacaga agtggatcag ctaaaccgct
     7681 taccctgaat attcagggta agcgtgagag ttaaaaaaga attacagcgg ttgggtttgc
     7741 gcttcaacca cggccagcgc caccatgttg acgatacgac gtaccgatgc gatcggcgtt
     7801 aacacgtgaa ccggcttcgc cacgcccatc agcaccggac cgacagtcac accttccgag
     7861 ctggaaacgc gcagtaagtt gtaactaatg cgggcagctt ccatgttcgg catcaccaga
     7921 atattagcgg aacctttcaa agggctgtcc ggcatacggt cgttgcgaat cgcttccacc
     7981 agcgctgcat cgccgtgcat ttcaccatca atcatcagtt ctggcgcacg ttccctgacc
     8041 agttccagcg cctgacgcat tttgctcgac gacgggcagt cagaagaacc aaagttggag
     8101 tgcgacaaca gagccacacg cggttcaata ccaaaacgac gaacagtttc tgccgccatc
     8161 aaggtgatct ccgccagctc ttctgcatca ggctcatcat tgacgtaggt atcggcaata
     8221 aaggtgttac cactcggcaa cagcagcgcg ttcatggcac ctgcggtgtg aacgccatcg
     8281 cgataaccaa agacattttt caccacgcta aagtgttcat gataatcgcc caccgtaccg
     8341 caaatcattg catcggcttc gccacgctga accatgatcg cgccgatcac tgtcgggtta
     8401 ctgatcagcg cacgctgcgc ctgctcctga gtgacaccgc gacgcttcat gatctggaag
     8461 tattcggtcc agtactcttt aaagcgcgga tcggattcgt tattgacgat ctcaaaatca
     8521 acgcccgcct tgatctgcaa gcccagtttc tgaatgcgca tttcgatcac gttcggacga
     8581 ccaataagaa tcggtttcgc cagtcccagc gttaccagtt cctgagtggc atgcagaacg
     8641 cgcgcctctt ccccttccgg cagaacgacg cgcttcggcg ctttgcgagc ctgggagaaa
     8701 atcggcttca taaacaggtt ggttttgtaa acgaactctg tcagcttgtc gatgtagacg
     8761 tcgaaatcag caatcggacg cgtcgccacg cccgactcca tcgccgcttt agcgaccgca
     8821 ggagcgatct taacgatcaa acgcggatca aacggttttg gaatgatgta ttccgggccg
     8881 aaactcagat cttgatcgcc atacgccgaa gcaacgactt cgctctgttc cgcatgggcc
     8941 agttctgcaa tcgcgcgtac tgccgccagt ttcatctctt cgttgatggc ggttgcgcca
     9001 acgtccagcg cgccacggaa gataaacggg aagcaaagga cgttgttcac ctggttcggg
     9061 tagtcggaac ggccggtaca gatgatggca tccggacgca cttctttcgc cagcggcggc
     9121 agaatttccg gttccggatt cgccagcgcc aggatcattg gtgcccgagc cattttcttc
     9181 accatttcct gggtcagcac tttcgggccg gaacagccga ggaaaatatc cgcaccttca
     9241 atcacatcat cgagggtacg tttgccgtca tccaccaccg catatgcggc tttggtttcc
     9301 gccatatttg gctcacggcc ctgatagata acgccttttg aatcacaaac cacgatgtta
     9361 tgtttttgca gccccagcgc caccagcagg ttcatacagg caattgctgc tgcacccgcg
     9421 ccggaaacca ccatccgcac gtcggagatg tttttctcca ccacgcgcaa tccgttgagg
     9481 atggcggcag tgctgataat tgccgtgccg tgctgatcgt cgtggaatac tggaatattc
     9541 atccgctcgc gcagtttctg ttcaatatag aaacattctg gcgctttaat gtcttcgagg
     9601 ttgatgccgc cgaaggtcgg ttcaagcgcg gcgacgactt caataaattt gtccgggtcg
     9661 agttcatcaa cttcaatgtc aaatacatca atcccggcga atttcttaaa cagaacgccc
     9721 ttgccttcca tcaccggttt gcctgccagc gcgccaatgt tgcctaaccc cagcaccgcc
     9781 gtaccgttag agatcaccgc caccaggtta ccacgcgcgg tatatttgta ggcttttaac
     9841 gggtcttttt cgatttcaag acaaggtgcg gcaacgcctg gtgagtaggc cagcgccaga
     9901 tcgcgctgcg ttgccagagg cttggttgga gaaacctgga ttttccctgg aactggaaat
     9961 tcatggaaat caagtgcact ttgttttaac tggtcatcca tttggttgtt cctttcacgt
    10021 aacgttcaca aataaagtgt gtgggcaaca gcccctgccc acaacgtggc gcacattatt
    10081 accctgccgg agtctacaga ctttgagcaa gtccaaactc tcaccattaa tataatgttt
    10141 tggtaataat cctataacac tgatgttacc tgcttaatcc agcaatacca tgcctgtctg
    10201 ctatgctttt ttgatgcgtt tagcgaaatt tctcagaagt gtgaattaac gcactcatct
    10261 aacactttac ttttcaagga gtatttccta tgaacgagtt agacggcatc aaacagttca
    10321 ccactgtcgt ggcagacagc ggcgatattg agtccattcg ccattatcat ccccaggatg
    10381 ccaccaccaa tccttcgctg ttactcaagg ctgccggatt atcacaatat gagcatttaa
    10441 tagacgatgc tatcgcctgg ggtaaaaaaa atggcaagac ccaggaacaa caggtggtcg
    10501 ctgcatgtga caaactggcg gtcaatttcg gtactgaaat tctcaaaatc gtacccggtc
    10561 gcgtgtcaac agaagttgat gcacgcctct cttttgataa agaaaagagt attgagaagg
    10621 cgcgccatct ggtggacttg tatcagcaac aaggcgttga gaaatcacgc attttgatca
    10681 agctggcttc aacctgggaa ggaattcgcg cggcagaaga gctggaaaaa gaaggtatta
    10741 actgcaacct gacgctgctg ttttcttttg ctcaggcgcg ggcctgtgca gaagcaggcg
    10801 tttttctgat ttcgccgttt gtcgggcgta tttatgactg gtatcaggcg cgtaagccga
    10861 tggacccgta tgtggtggaa gaagatccgg gcgttaagtc agtgcgcaat atctacgact
    10921 actataagca acaccactac gaaaccattg taatgggcgc gagcttccgt cgcaccgaac
    10981 aaatcctcgc cttaaccggc tgcgaccgac tgactatcgc accgaatttg ctgaaggagc
    11041 tacaggaaaa agtttcgcca gtggtacgta aattaatccc atcttctcag acgttcccac
    11101 gcccagctcc catgagcgaa gcggagttcc gttgggagca caatcaggat gcgatggcgg
    11161 tagaaaaact gtctgaaggc attcgtctat tcgccgttga tcaacgcaaa ctggaagatc
    11221 ttcttgccgc caaactataa accagccacg gagtgttata tgtcccgaaa agaccttgcc
    11281 aatgcgattc gcgcactcag tatggatgcg gtgcaaaaag ccaattctgg tcatcccggc
    11341 gcgccgatgg gcatggccga tattgccgaa gtgctgtgga acgattttct taaacataac
    11401 cctaccgacc caacctggta tgatcgcgac cgctttattc tttccaacgg tcacgcgtcg
    11461 atgctgctct acagtttgct gcatctgacc ggttacgacc tgccgctgga agaactgaag
    11521 aacttccgtc agttgcattc gaaaacccca ggccacccgg aaatcggcta tacgcctggt
    11581 gttgaaacca ccaccggtcc acttggacaa ggtttggcga acgccgtcgg gctggcgata
    11641 gcagagcgta cgctggcggc gcagtttaac cagccagatc atgaaattgt cgatcacttc
    11701 acctatgtgt ttatgggcga cggctgcctg atggaaggta tttcccacga agtctgttcg
    11761 ctggcgggca cgctgggact gggcaagctg attggttttt acgatcacaa cggtatttcc
    11821 atcgacggtg aaaccgaagg ctggtttacc gacgatacag caaaacgttt tgaagcctat
    11881 cactggcatg tgatccacga gatcgacggt cacgatccgc aggcggtgaa ggaagcgatc
    11941 cttgaagcgc aaagcgtgaa agataagccg tcgctgatta tctgccgtac ggtgattggc
    12001 tttggttcgc cgaataaagc aggtaaggaa gaggcgcacg gcgcaccact gggggaagaa
    12061 gaagtggcgc tggcacggca aaaactgggc tggcaccatc cgccatttga gatccctaaa
    12121 gagatttatc acgcctggga tgcccgcgaa aaaggcgaaa aagcgcagca gagctggaat
    12181 gagaagtttg ccgcctataa aaaggctcat ccgcaactgg cagaagagtt tacccgtcgg
    12241 atgagcggtg gtttaccgaa ggactgggag aaaacgactc agaaatatat caatgagttg
    12301 caggcgaatc cggcgaaaat cgctacccgt aaggcttcgc aaaatacgct taacgcttac
    12361 gggcctatgc taccggagct gctcggcggt tcggcggatc tggctcccag caacctgacc
    12421 atctggaaag gttctgtgtc gctgaaggag gatccggcgg gcaactacat tcactacggg
    12481 gtgcgggaat ttggcatgac cgctatcgcc aacggcattg cgcaccacgg cggctttgtg
    12541 ccgtataccg cgacattcct gatgtttgtt gaatacgccc gtaacgccgc gcggatggcg
    12601 gcactgatga aagcgcggca gattatggtt tatacccacg actcaattgg cctgggcgaa
    12661 gatggtccta cgcaccaggc tgttgagcaa ctggccagtc tgcgcttaac gccaaatttc
    12721 agcacctggc gaccgtgcga tcaggtggaa gcagcggtgg gctggaagct ggcggttgag
    12781 cgccacaacg gaccgacggc actgatcctc tccaggcaga atctggccca ggtggaacgt
    12841 acgccggatc aggttaaaga gattgctcgt ggcggttatg tactgaaaga cagcggcggt
    12901 aagccagata ttattttgat tgccaccggt tcagagatgg aaatcaccct gcaagcggca
    12961 gagaaattag cgggagaagg tcgcaatgta cgcgtagttt ccctgccctc gaccgatatt
    13021 ttcgacgccc aggatgagga atatcgggag tcggtgttgc cttctaacgt tgcggctcgc
    13081 gtagcggtgg aagcaggcat cgccgattac tggtacaagt atgttggtct gaaaggggca
    13141 attgtcggga tgacaggtta tggggaatct gctccggcgg ataagctgtt cccgttcttt
    13201 ggctttaccg ccgagaatat tgtggcaaaa gcgcataagg tgctgggagt gaaaggtgcc
    13261 tgatggtgat cgccggatgc tgtatgttcc cctcacccta accctctccc cagaggggcg
    13321 aggggacggt ccgtgcgctt tttagggccg catctgcgat tttgtttaac gggtgatcca
    13381 caacgtgggc caggcgtctg gcccatgcca gttatcgcag gtgggttctg cggcgtaacg
    13441 caccaggcga aaacgctgac cgtcaaagcg ccagcgcgcc tgaatgccac aatcgcttaa
    13501 tccgcgccct ttcgctaagg tcaccagttc acgcgatttt tcatcgaatg ttgcgttcat
    13561 cagttccagt tcattcgtct cctgaccgtt gttgaacggc aaacgcaacc gaaccgggcg
    13621 cgaggctagc ggctttttac gcgacacaat ccatgccaaa tcaatggtgt tataggcccc
    13681 tgcctcacag ctaatcatca tcagtgcttt atcatcggtc agcgcagtga cattcacctc
    13741 acgacgtaac ggatcaagcg agcagcgcag accattcatc cgccagtttc cataatccag
    13801 caaatcgttg cgttcttcga gtgagagtgg cgtcggcgtt gggttaacca ccgcgacctc
    13861 tttcagcgca ggcgcaggcg gtacgctgag cggcggttcg tcccctttct ttatccacgc
    13921 ggtttcactg ccaacgcgct tttgctgagc atcaataaac aacaacgccg cttttaagcc
    13981 attcagagaa atggtctgat tgccatcgcg taaggtgatt gccttccctt cctgaatcag
    14041 ctgcaaaaac gcggtgatgg ttgccgtatc atcggttact agtaaccatg gtgaaattcg
    14101 ccacttgtca ccacttaacg ccaacggctc accatctaac agcagccgtg gcgctatctc
    14161 cccttcagac gcatccggcg acttcaaccc gccgcgctca atacgtaaaa cggcatcggt
    14221 atgcgccccg gcgctgcggc tcagggtcat caccagtcca ttatgatcgc ccgtattgcg
    14281 cgctacacag aaattttggt tattacaggt aacctgccag tcggaaaacg cccgttgcgc
    14341 tggtgccgcc cacaccaaag acgtcggcaa caaagcgaaa aaaaagagaa ggaaaatgcg
    14401 atagcgcatg gacggtacga ccccagaagt tcaaacaaac agcacaagtc gtatcttcgt
    14461 tgcgcaggta gcgcggctca atcggatttg tcggattgag ccaataataa acaacgaaat
    14521 attattgtta tttttcagtc cattaaatgt gacgtttgca aatagttaag caataacacc
    14581 gtcttaccgt cacgtatctc gccggttttg atcatctcca gcgcctggct gaacggcagc
    14641 tcgagcactt caatatcttc atcttcgaca ccaccgcccg cgttagcgcg ctggctgtca
    14701 ctgtattcgg cgataaaaaa gtggattagc tcagtcacac cgccaggcga catatacagt
    14761 tcaaataatt tgcgcacttc gcccacttca tagcccgtct cttcaatcgc ttctttgcga
    14821 atgcacactt ccggttcgtc gttatccagc agcccggcgc aggtttcaat cagctgcccg
    14881 ctttcattgc cattaaccca ggtagcgaca cggaactgac gaatcagaac cacggtcttt
    14941 ttcttcgcgt tgtacaggag gatcgtcgca ccattaccgc gatcgtaaac ttcacgttta
    15001 tggcggataa cttcgccatc tttgcgcgtg agatcgtaag taatgttgtg cagggtgaaa
    15061 tagttatcgg agagaatttt gtctttaatg agggtgattt gttgcgtcat accgactcca
    15121 cagcgcgaaa tgaacaatta tcttacgctg tgaagtcggg tttgtctgcg caggctatca
    15181 gtgagatttg actgatttta cccccagcca gtcaataatc ccctgtgccg catgacgtcc
    15241 ttctgccatt gcggtaacca ccagatccgc accacgcacg gcgtcaccac cggcgaagat
    15301 tttcggattg gtggtctggt aacggtactg gctttccaca tccgcgatga tgcggcccca
    15361 tttgtctacc gttacaccgt gcgactccag ccacggcatc ccgtgtggat tgaagccaaa
    15421 cgccataatc accgcgtcgg ctggcatgac aaattcactg ccttccaccg gcactggacg
    15481 ccgacgcccc tgggcatccg gctcgccaag actcgtacgc aggaaacgaa ttccgcaaac
    15541 gtgaccttgt tcattcagct caagcgccac cggctggacg ttaaattcga agttggcccc
    15601 ctcttcgcgg gcgttcttca cctctttctt cgagcctggc atgttagctt catcacgacg
    15661 ataagcgcag gtgacgttac tcgcgccgtg gcgcagcgcg gtacgcacac agtccatcgc
    15721 ggtgtcgccg ccgcccagta ccacgacgtt gagtccggcg gtattgataa acggctcttc
    15781 cggtagctct tcgagtccca tcacctgttt agtgttggcg atgaggaacg gcagggcgtc
    15841 ataaacgccc ggcgcatctt cattgggtaa acccgctttc atggaacggt aagtgcctac
    15901 gccaacgaag accgcgtcgt attgttccaa aagcgaatcc aaagagacat ctttacccac
    15961 ttcacaattg agttcgaagt gaatccccat cgcgctgaag atttcccgac ggcgtgccag
    16021 cagggattta tccagtttga aagaaggaat gccgaaagtg agcaagccac cgatttctgg
    16081 atggcgatcg tacaccgtca cctctacgcc attgcgggtc agaacatccg cacaggccag
    16141 ccctgccgga cccgcaccga taatcgccac tcgcttgtcc actttggtga catgacttaa
    16201 gtcagaacgc caacctttcg ccaacgcctg atctgaaatg tagcgttcaa tgttgccgat
    16261 agttactgcg ccgtgctcat cgcgaatagt acaggcacct tcacacaaac ggtcttgcgg
    16321 gcaaacgcgt ccggtaattt ccggcagggt gttggtctgg tgagaaagct cgacggcggc
    16381 gtcgatgttt ccggctttca ccagttcaat ccactgcggt atatggttat gcagcgggca
    16441 ggtccattca caaacgctgt gctcgccgca cttaaggcag cgcgaggctt cccgttgtgc
    16501 ctgatcggca cggaatggca gataaatttc atcaaaaccg gttttgcgcg cttcaatcgc
    16561 cagtttgtcc ggctcgccac gcgcgggcgt tgcctgcatt tgctcgactt tactcattac
    16621 cggcatttct tgtgccgcgg tactggcatg ccacggttga tgttcctgac gtgctgtgcg
    16681 caagcggcgg gatttcgcta tgccggagag tgcggcatca gtgaccagtt gcagcgcgtc
    16741 tgccgggcaa ttctcgacac aggcaggacc gttttcgcgc cctgcacaaa ggtcgcattt
    16801 atgcgccgtg gctttaactt tgccagccgc aacgggtgtc aggacgattt gcatcgtacc
    16861 aaatggacag gccaccacgc aggatttaca gccaatacac ttttgctgat tgacctgaat
    16921 gctgtcatca acgtggctga ttgcgccatt agggcagcta cgggcgcagg gcgcatcttc
    16981 acaatggtga caggtcactg cactacgttg ctgctgatgt ttgataaccg taattcgggg
    17041 atgaaaatgg cgttggctca ggacatgttg ctcgtcattg tgagccatga cacaggcgat
    17101 ttcacaagca tgacaaccca gacattgctg actgttggcc ataataaaac gattcataac
    17161 gaccttcttt tttggttgta aaaaccttat tctttatatg agtgttgtta ttacccgact
    17221 tacaggggaa tcggcaatgt tcatgtgccc agaataagta actatttcgc tataaactgt
    17281 ggcagatcaa ataatcccat cactgactaa attgcgtttc agcgaactgg aacattaatg
    17341 attttttgtg gagaagacgc gtgtgattgt taaacgaccc gtctcggcca gtctggcccg
    17401 ggcctttttt tacattgtgc tgctgtcgat tctttccacg ggtatcgctc tgctaacgct
    17461 ggcgagcagt ttacgcgacg ctgaggctat caatattgcc ggatcgctgc gtatgcagag
    17521 ttaccgcctg ggctacgact tgcaaagtgg cagtccacaa ctcaatgcac atcgccagtt
    17581 atttcagcag gcactgcatt caccggtatt aaccaatctc aacgtctggt atgtgccaga
    17641 ggcagtaaaa acccgctatg cgcatctgaa tgccaactgg ctggagatga ataatcggct
    17701 cagcaagggc gacttgccgt ggtatcaggc caatattaat aattatgtta atcagataga
    17761 cctgttcgtg ctggctttac agcactacgc tgaacgcaaa atgctgctgg tggtggcaat
    17821 ttccctggct ggcggcatcg gtattttcac gctggtcttt tttactttgc gccgcatacg
    17881 ccatcaggtg gttgccccgc tgaatcagct ggttaccgcc agtcagcgta ttgaacacgg
    17941 gcagttcgac tcgccaccgc tggataccag cctgccgaat gagcttggcc tgcttgcaaa
    18001 aacctttaac cagatgtcga gcgagctaca taaattgtac cgttcgctgg aggcgtcagt
    18061 agaagaaaag acccgcgatc tccacgaggc caagcgtcgt ctggaggtgt tgtatcagtg
    18121 ttcgcaggcg ctgaacacca gccagattga tgtgcattgt ttccgccata ttttgcagat
    18181 tgttcgcgac aatgaagcgg ctgaatatct ggagttaaat gtcggtgaca actggcggat
    18241 tagcgaaggg cagccaaacc cggaattgcc gatgcagatt ttaccggtga caatgcaaga
    18301 gacggtttac ggcgaactgc actggcaaaa tagtcacgtt tcatcatcag aaccgctgct
    18361 taacagcgtt tcgtcgatgc tgggacgcgg tttgtacttt aatcaggcgc agaagcattt
    18421 tcagcagtta ttgttgatgg aagaacgtgc gaccatcgcc cgcgaattgc acgactcgct
    18481 ggctcaggta ctttcttact tacgtatcca gttgacgtta ctgaagcgtt cgataccgga
    18541 agataacgcc accgcacaaa gtatcatggc cgatttttcc caggcgttga atgatgctta
    18601 tcggcagtta cgcgagctgt tgactacttt ccgcctgacg ctacagcagg cggatctccc
    18661 ctccgcgttg agggaaatgc tggatacgtt acaaaatcaa accagcgcca aactgaccct
    18721 cgactgccgt ctgccaaccc tggcgctgga tgcgcaaatg caggtgcatt tgttgcaaat
    18781 tattcgcgaa gcggtgctga atgcgatgaa gcacgccaac gccagcgaaa tcgccgttag
    18841 ctgcgtcaca gcgccggatg gcaatcacac agtctatatt cgcgacaacg ggattggcat
    18901 cggtgaaccg aaagaacccg aaggccatta tggtctgaat atcatgcgcg aacgcgcgga
    18961 aagattgggt gggacgctga ctttttcgca accttccggc ggcggcacgt tagtgagtat
    19021 tagctttcgc tctgcggagg gtgaggaaag tcagctgatg taatgcctct tattgaccaa
    19081 agaatagtgg cacttaaggt tcagtataaa agggcatgat aatttacatt aactcctttt
    19141 tttctccacg attggctcgt accttgccgc tacagtgaag caagtcaagc ctacaacgat
    19201 acgcagaaac acgaggtcct cttttaatgg cgaatttctt tattgatcgc cccatttttg
    19261 cctgggtgct ggcaatcctg ttgtgtctga cagggaccct ggcgattttt tcattgcccg
    19321 ttgaacaata ccccgatctc gcgccaccga atgtgcgagt gaccgctaac tatcccggcg
    19381 catcggccca gacgctggaa aacaccgtga cccaggttat cgagcaaaat atgaccggcc
    19441 tcgataatct gatgtatatg tcatctcaga gcagcggcac cggtcaggca tctgtcacgt
    19501 taagttttaa agcaggcacc gatccggacg aagccgtgca gcaagtacaa aaccagctac
    19561 aatcagccat gcgaaagtta ccgcaggcgg tgcaaaatca gggcgtgacg gtgcgtaaaa
    19621 ccggcgatac caacattctg accattgcct tcgtctctac cgatggttcg atggataaac
    19681 aggatattgc cgattacgtt gccagtaata ttcaggatcc gttaagccgc gtgaatggcg
    19741 tcggggatat cgatgcctat ggttcgcaat attccatgcg tatctggctg gacccggcga
    19801 aactcaacag tttccagatg acggctaaag atgtcactga tgccattgag tcacagaacg
    19861 cgcagattgc ggttgggcaa cttggtggta cgccttccgt cgataagcag gcgctcaacg
    19921 ccaccattaa cgcccagtca ctgctgcaaa caccagaaca gttccgcgat atcaccttgc
    19981 gggtgaatca ggacggctca gaggtaaggc tgggcgatgt cgccaccgtc gaaatggggg
    20041 cggaaaaata cgattatctt agccgcttca atggtaagcc agcctccggg ctgggggtaa
    20101 aactggcctc cggcgcgaac gaaatggcga cagcggagct ggtgctcaat cgtctcgacg
    20161 agctggcgca gtatttcccg cacggactgg aatacaaggt ggcgtatgaa accacctcgt
    20221 ttgttaaagc ctccattgaa gacgtggtga aaacgctgct ggaagctatc gctctggttt
    20281 tcctcgttat gtatctgttc ctgcaaaact tccgcgccac gctgataccc actatcgccg
    20341 tgccggtggt gttgatggga accttctccg tactttatgc cttcggttac agcgtcaaca
    20401 ccttaaccat gttcgcgatg gtgctggcga tcggtctgct ggtggatgat gccatcgtgg
    20461 tggtggaaaa cgtcgaacgt attatgagtg aggaaggact cactcctcgc gaagccacac
    20521 gtaaatcgat ggggcagatc cagggggcac tggtcgggat tgcgatggtg ctttcggcgg
    20581 tatttgtacc aatggccttc ttcggcggca ccaccggtgc catctatcgc cagttctcta
    20641 ttaccattgt tgcagcaatg gtgctgtcag tactggtagc gatgatcctc actccggctc
    20701 tgtgtgccac gctacttaag ccactgaaaa aaggtgagca tcacgggcaa aaaggctttt
    20761 ttgcctggtt taaccagatg tttaaccgca acgccgaacg ctacgaaaaa ggggtggcga
    20821 aaattctcca ccgtagcctg cgctggattg tgatttatgt cctgctgctt ggcggcatgg
    20881 tgttcctgtt cctgcgtttg ccgacgtcgt tcttgccact tgaagaccgt ggcatgttta
    20941 ctacctcggt acagttgccc agcggttcaa cccaacaaca gaccctgaaa gtcgttgagc
    21001 aaatcgagaa atactacttc acccatgaaa aagacaacat catgtcggtg tttgccactg
    21061 ttggttctgg ccctgggggt aacgggcaaa acgtggcgag aatgtttatc cgcctgaaag
    21121 actggagcga acgcgacagt aagaccggca cctcgtttgc cattatcgag cgtgcaacga
    21181 aggcgtttaa caagattaaa gaagctcgcg ttatcgccag cagcccgcca gcaattagcg
    21241 gtcttggtag ttctgcgggt tttgatatgg agttgcagga ccacgctgga gcgggtcacg
    21301 atgcgctgat ggcagcacga aaccagttgc tggcgctggc agcggaaaac ccggagctaa
    21361 cccgtgtgcg ccataacggc ctcgacgaca gtccgcagtt gcagattgat atcgaccagc
    21421 gtaaagctca ggcgctgggc gttgctatcg acgatattaa cgacacactg caaaccgcct
    21481 ggggttcgag ctatgtgaat gactttatgg atcgcggtcg cgtgaagaaa gtctatgtgc
    21541 aggcagctgc gccgtatcgc atgctgccag atgacatcaa tctctggtat gtccgaaata
    21601 aagatggcgg catggtgccc ttctctgctt tcgcgacctc acgctgggag acaggctcgc
    21661 cgcgtctgga acgctataac ggttattctg cggtagagat tgtaggggaa gccgcaccgg
    21721 gggtcagtac cggtacggcg atggatatta tggaatcgtt agtgaagcag ttaccaaacg
    21781 gctttggtct ggagtggacg gcgatgtcgt atcaggagcg gctttccggc gcgcaggctc
    21841 cggcgctgta cgctatttcc ttgctggtgg tattcctgtg tcttgcggcg ttgtatgaaa
    21901 gctggtcggt gccgttctcg gtaatgctgg tcgtgccgct gggggttatc ggcgcgctgc
    21961 tggcaacctg gatgcgcggg ctggaaaacg acgtttactt ccaggtgggc ctgttaacgg
    22021 tcattggttt atcggcgaaa aacgccatcc tgatcgtcga gtttgctaac gagatgaacc
    22081 aaaaaggcca cgacctgttt gaagcgacgc tccacgcctg ccgtcagcgt ttacgcccga
    22141 ttctgatgac ttcgctggca tttatcttcg gcgtattgcc aatggcaacc agcacgggtg
    22201 ccggttccgg tggtcagcat gcggtgggta ctggcgtaat gggcgggatg atttcggcca
    22261 ctattctggc tatttacttc gtgccgctgt tctttgtgct ggtgcgccgc cgcttcccgc
    22321 tgaagccgcg cccggaataa gcaataaaaa aggcgacatg ctaatgtgtc gcctttttca
    22381 actttccgat taagaacctg ctcagcgggt tcttgctgtt tgtactttgt ctcaggaatt
    22441 acttacgaag cataacttcg ataaagtctt tccagttccc cagttcacgt tcaatcataa
    22501 caacctctct tataattatg ggtattctac ggaaacaata taccgtggtg aagctaattt
    22561 actcgattgc tgcgatgact acctccgggg gacaaacctt atgtaaatac tatggtcctg
    22621 cggtgataat ttgtatgtga tacacagcaa catttcgaga tattcatacg gcatctaata
    22681 ctgatttaat tctggttaaa atacagacag ataacaagat gaatattctt aatgtttacg
    22741 ttaaaaatgt ttaatgttat ttaatagttg ttaatttgaa tacttcgata atgttatatt
    22801 tcctgataat catttgcagg caaaatgttt tcacccttaa atgagtattt attctcataa
    22861 atcgaaaaag gattcattat ggttacactt tacggcatca aaaattgtga caccattaaa
    22921 aaggctcgcc gttggctgga agccaataac atcgactatc gttttcatga ttaccgcgtc
    22981 gatggattgg acagcgaatt attgaacggt tttatcaacg aattaggctg ggaagcgtta
    23041 ctcaacaccc gtggtacaac ctggcgtaaa ctggacgaaa ccacccgcaa taaaatcacc
    23101 gatgcggcct ctgcggcgac attaatgact gaaatgcctg caattatcaa acgtccattg
    23161 ctctgcgcgc ctggtaagcc tatgctgctg ggtttcagtg aatccagtta tcagcaattt
    23221 ttccatgagg tgtagtctat gtcgtgcccg gttattgagc tgacacaaca gcttattcgc
    23281 cgcccttccc tgagtcctga tgacgcagga tgccaggctt tgttgattga acgtttgcag
    23341 gcgatcggtt ttaccgttga acgcatggac tttgccgata cgcagaattt ttgggcatgg
    23401 cgtgggcagg gtgaaacgtt agcctttgcc gggcataccg acgtggtgcc gcctggcgac
    23461 gccgaccgtt ggatcaatcc gccgtttgaa cccaccattc gtgacggcat gttattcggg
    23521 cgcggtgcgg cagatatgaa aggctcgctg gcagcgatgg tggtagcggc agaacgcttt
    23581 gtcgcacaac atcccaacca tgcaggtcga ctggcatttc tgatcacctc tgatgaagaa
    23641 gccagtgccc acaacggtac ggtaaaagtc gtcgaggcgt taatggcacg taatgagcgt
    23701 ctcgattact gcctggtcgg cgaaccgtcg agtatcgaag tggtaggtga tgtggtgaaa
    23761 aatggtcgtc gcggatcgtt aacctgcaac ctcaccattc atggcgtgca ggggcatgtt
    23821 gcctacccac atctggctga caatccggta catcgcgcag cacctttcct taatgaatta
    23881 gtggctattg agtgggatca gggcaatgaa ttcttcccgg cgaccagtat gcagattgcc
    23941 aatattcagg cgggaacggg cagtaacaac gttattccgg gtgaactgtt tgtgcagttt
    24001 aacttccgct tcagcaccga actgactgat gagatgatca aagcgcaggt gcttgccctg
    24061 cttgaaaaac atcaactgcg ctatacggtg gattggtggc tttccgggca gccatttttg
    24121 accgcacgcg gtaaactggt ggatgcggtc gttaacgcgg ttgagcacta taatgaaatt
    24181 aaaccgcagc tactgaccac aggcggaacg tccgacgggc gctttattgc ccgcatgggg
    24241 gcgcaggtgg tggaactcgg gccggtcaat gccactattc ataaaattaa tgaatgtgtg
    24301 aacgctgccg acctgcagct acttgcccgt atgtatcaac gtatcatgga acagctcgtc
    24361 gcgtgatgag tggttccgca agaggaaata agcatggact ggctggctaa atattggtgg
    24421 attctggtga ttgtcttttt ggtaggcgtc ctgctgaacg tgattaaaga tctcaagcgc
    24481 gtcgaccata agaaatttct cgccaacaag ccggagcttc ccccgcatcg tgatttcaac
    24541 gataagtggg acgatgacga cgactggccg aaaaaggatc aaccgaagaa gtaagctaag
    24601 tggccggata aggcgttaac gccgcatccg gccatgatgc ctgatacagt cttatcagac
    24661 ctacccggct attattacat catttcaatc acatcatcat cgccaggctt accgccgctt
    24721 agcgcttcgt cgaaataatg tttcggaatg gtataacgca agtgatccag agcaaattgc
    24781 atactgcgat tgtcgatcgc atggcctaaa tcctccacga tatccagcgt cacgtcacca
    24841 ccggcactga ttaacgcttc ctgcgccgca accgcatgcg ccagatcgat aaccggatct
    24901 tcaccgccat gaatcaggtg aattgtcgtg gctgtagacg cggtttccgg caggctcgca
    24961 tagcgtccgt taaaggcaat gacgcgtgag gcaaggcccg gttcggcttt aatgctctcc
    25021 agcgccataa tcgcgccttg agagaaaccg attagcgccg tggcgttagc ccctactccg
    25081 ctctgtttct gccagtagcg caccgtctca ataaacgtcg gcatgatggc atccacacgc
    25141 gcctggcgat tatcttccgt aataccctgc accgaaaacc actgacgccc cgccggatta
    25201 ccgctcggct ccgcgcctcc gacactcacc accagcgcat caggaaatag cggcgcaaac
    25261 cagctaccta tttcccccat tgccaccggg ttatccccga caccgtggaa aagcagtaac
    25321 aactgttgcg caggtttatc cgggctttga acaacaaaat ggtcatgttt catggcgaac
    25381 tccttaactg atgtcattaa ttttacgccg ctgactcaca atgaccatgg gagaaaattg
    25441 aaggagtcag tgaaaaaatt gccattgcgt tatgcgatcg cgcaaacgct cagtgcgaac
    25501 atcatcaagt gcgtatagcg cctgcgcggc ctcttcccgc tgacggacca gtaacagctt
    25561 acggcctgaa agtttaagtg tggtacataa ctgcgcgtca ctggcgtttt tctgtaaacg
    25621 tccacgcagc gccggtaatg ccatttcgct ggtttgtaac agacgcatta agcaacctaa
    25681 cgacgttaat agcggacgat gagcgaaagc aaaaccggcc agttcaagcc agtcgtcgtc
    25741 agaaaggacg gcatcgttta gtggatcaac aggaagcgtt tcgccattcc actttgcgag
    25801 agcttgcgca tcgcgacgta aacggtaatg ctcaccttca gccagttgtt tacccgcatc
    25861 actcatcggt aacagcgcca tcgccgtata gcaaccgctg ctggcttcac gatgattacc
    25921 cattcgcacc agcacaaaac cgcagcgttg ccagaaacgc cataattccc cggtgtaacc
    25981 aaaactcacc gaaagatagt cgaggtcatg cgtatattgc aaagcaccag caatcagttg
    26041 ctgacctgtg ccttcccgct gacgagccgg atgaactgct atccggctaa cccgccttcc
    26101 gcgcaatgtc gccgccagtg gattgctgcc gtgcgccgcc agcgactggg ccaccagatt
    26161 accccgcggg cgacgaaaac ctgcccatac cgcctgactg agttcttgag ataatccgcc
    26221 ctcatccacc agccacagcg ccccggcaat cgcgttttcg ccagccgcct gtaaaaaatg
    26281 ttgccctggt gcatccatca tgcggcgtaa atccagcggc gaagtccggt agtgcgcacc
    26341 agacaataat tgataaacct ttaacggcgt ttgtggctcg cttcgccata acgtctgttc
    26401 aaatgcggaa atgacgatat tgccttgtgg tgtgtgggtg aagttttcat cgtcaaaaac
    26461 cagtgcctca ctaaccattt tttccagcgg gcatccctgt gcccagcgga tcggctgttg
    26521 cagttcaaaa cggtgtaaat gcggaaagcg agcgcaaaat ttcagcaaaa aaccacgtcc
    26581 cgtgccttcg tagccctgca ccgtagtggt taacaacgtt cgaggaaaac gcgataccag
    26641 ttgatgcaac aacggcgcag gtatggctgc ggcttcatcg accaccagcc agtcggcttg
    26701 ctcatcgctg gctatcaagg catccggtgc aataaagcga aacttctcgc ccgcaaattg
    26761 tgccagtaca tccgttgccg cttttgcggg cgcggtgaca atcgcactgc ccgcaatacg
    26821 agaaataagt tgccctgcca acgccgactt accgcgccca cgcgcagcag ttaccgctgc
    26881 cacgcccggc ggcatggtca gtagctgctg taagagttgc tgttgttctg gttgtggtgc
    26941 gccggtcgcg gggtgccagt cagtacgggg agtaaaatgc gccaacgaga acggctggtt
    27001 ttgccgccag aggatagcgt cgttattcgc cgtaattacg cgtttgaaat gctggacaaa
    27061 atgcggcgtc gcaatagggt cagggcaatc actccagcgc agcgagtcgg catcaggttg
    27121 gttatcccac tcttcccata cagggagtaa caaaaccagc cagcttcccg ctttcaacgt
    27181 tccgctaagt gccgcaaagg cagcggcatc aaagccgtgg cgggcgtcga ataccgcatg
    27241 ccggaactcg cgcccaagta aagtttgtag cgccgaggga aaacagtggt tttcagcgac
    27301 tggctgcggc gaaatccaca gccagtcgcc aggtaaggca tcacgcaact taagcgcatg
    27361 atcaaaacac caaccctctt ccccgctcaa caccagcaag cggcggatcc cttcacgttt
    27421 catttgcgct gttaatgtgt gaagcgcagt cagttcagcc atccctgccc cggaagttaa
    27481 atgcttttac caaaagtatt gcattgtgcc ggatcgccac tgtcgaaacc acgtttaaac
    27541 cagctgtagc gttgctgaga agtgccatgt gtgaaactgt ctggtactac tcgcccctga
    27601 ctttgctgtt gtaaacggtc atcgccgatg gcctgcgccg cgttcagcgc ctcttccaga
    27661 tcgccggttt ccagaacacc ttgctgctgc atactatgcc cccagacacc ggcaaaacag
    27721 tcggcctgga gttccatacg cacagataag cggttcactt ccgcctgcgt cgcgttttgt
    27781 tgcagttgac gaactttcgg ctcgatgcct aacagtttct gcacatgatg accgacttca
    27841 tgggcgataa cgtacccctg ggcaaaatcg ccatccgcgc caagtttgtc tttcatgtca
    27901 tcatagaagg agagatcgat ataaaccgtg ccatccgccg ggcaatagaa cggtcccata
    27961 atggattggc ccgccccgca gccggtgcgc gtcattccac ggtacatgac cagcttcggt
    28021 tgctgatagg ttttacccat cttctcgaat tgctgtcccc aggtgtcttc cgtggttgcc
    28081 aaaatcaccg aagtgaattt tgcggcttcg tcttcattag gactaattga ccgtgttgat
    28141 tgctgttggg aaaccggctg tccggtcatc aacccggtta aatcaacgcc atagtagcct
    28201 gcaaccagca cgactatcag taaaatcagc ccgcctttac cgcttggcag gcgaaaacct
    28261 ggaccgccca ttgacggacc gccggagcta ttgcgcctgt cttcaacatt gtcactttca
    28321 cgtcgccctt gccaacgcat agatacctca acaatatatt cattatagaa atgatcgtag
    28381 gtggttcaga ggaagattac cacaggaaag cgggatgaaa tggcggagga atgagcgttc
    28441 aatactcatc ttatgagagc ggttgtcttg ccgtgccagc agcacggcaa gatgatgaat
    28501 aaaaaaatca gtccagctgt acacccaagc ggcgggcaac ggcttcatag gcttcgatca
    28561 ggccaccgag gctctggcgg aaacggtctt tgtccatttt ctccagcgtt tctttgtccc
    28621 acagacggct gccgtccggg gagaactcat cgcccagaac tacttcgcct ttgtacagac
    28681 caaactccag cttgaagtcg accagaatga gaccagcatc atcgaacagt tttttcagca
    28741 cgtcgttcgc tttgtaggtc agctctttca tacgcgccag gttctctttg ctcacccagc
    28801 caaaggtttc gcagtaagat tcgttgacca tcggatcgtg catggcgtcg tttttcagga
    28861 acagatcgaa cagtggcggg ttcagctcaa taccttcttc gattccaaga cgtttcacca
    28921 gagagccagc agcacggtta cgcacgacac actcaaccgg caccatatcc agctttttca
    28981 ccagacattc ggtatcggag agcagacgct ccatttgagt cgggataccc gcttcagcca
    29041 gtttgctcat aatgaagtag ttgaacttgt tgttcaccat acctttgcga tcaaactgct
    29101 caatgcgcgc gccatcccct gctgacgtat cattgcggaa ttcgagcacc aacaggtccg
    29161 ggttttccgt gctgtatacg gttttcgctt taccacgata caactcagct tgcttttgca
    29221 tctttatcac tcctgggtgt gaattaacgt tttaaaatct attgctgtct ggtgtgccgg
    29281 atgttttgtc ggatgcggcg tgaacgcctt atccgaccta cgtccgacaa acaaatttcg
    29341 tgcgaattac cgctaaaatc gcgtttttct gccgacgcac acgtttgcgt atcatatcag
    29401 aaaaaagggc cggatgactc cagccctgta tttttacttg ctaaacgcag cctggaagac
    29461 agctaccagc gcgtcgttct gactctgagt cagagtatga cctttcggat cgatgaactg
    29521 taggctgctg cggttatcta aatcgccaac ctgcagttta tagtcaccgg atgccagacc
    29581 tggatcgctc gcgcccagtt cgtgccattc gctgtcagac agcggcttgt aagttacggc
    29641 catgttgccc tgcgaacggg tgctgtcggt cactttcatg cccacttttt ccagcgcagc
    29701 tggcagacgt tgccaaacca cattgaacgg cccgcgtacg accagcattg gtaaaccggt
    29761 gtcatcagct gcactttgta cgtccatagt ggtggaggca cgattttgcg cagcgttcgc
    29821 ggcgtcagtg gcagatttat ccagaccggc ggaaataacg ttcatcatct ccgtgctgta
    29881 acgctgcatg gaagccgcgt ctgcaaccgg tttgcccgcc tgttccaggt tcagcagttt
    29941 aaccgtaacc gcctgctgat aaccctgcgg cttaacagag atttgataac gaccacgata
    30001 ctgctcgtct tcgtccagac ggttccattg tacccaatcg gtggtcagtg tctgaccagc
    30061 atcatcacgt tgggtgatgg tgtagttttt cgcctgcagc acgctaacca cctgcggcca
    30121 cagagtattg ccacgaccat tttccaccag caatgaagcg gtatcgcccg tgaactgggt
    30181 acgcgcgcca gaaaccagtg ccagcggctg ggctggtgga cgaatgtcca gcgccttacc
    30241 gacagcacca ctaccgttgg tcaccgggat tgcataatca ccggaggtca ccggcaaaat
    30301 cattccagcc ggggcatgaa gctccgcaag cggtgccgct tccaggtagg cttcatcacc
    30361 actgacctga cgcttatagc gtgagtcaga actacaggca gcgagtaata aaacaagcga
    30421 aacacccgca acctttgcca ggcgcgactt ttgaacagag taagccatca aatctcccta
    30481 aactttacag caaaccggca tgcttaagcg ccgctctgac cgtctcacga ccactgtcgg
    30541 tgattggtgt cattggcagg cgcagcgtat cggtcgccac aagacccagt tccttacatg
    30601 cccatttcac agggattgga ttgggttcga caaatagttt gttgtgtaat ggcatcagac
    30661 gctgattaat aacgcgtgcc tcggcaaaat gcccttctgc tgccagtttg cacatctggg
    30721 ccatatcacg cgctgcgacg ttagccgtaa cggaaataac cccatgaccg cccaattgca
    30781 tgaagtccag cgcgctcgca tcatcgccgc tcagcagaac aaaatcatct gaaaccagct
    30841 ctttgatctg gtttacacgc gttaagttcc ctgttgcctc tttgattccg ataatatttt
    30901 ttactttcgc cagacggccc accgtttccg ggagcagatc gcagccagta cgggacggca
    30961 cattatacag aatttgcggc aggtcagtat gttcagcgat ggctttgaaa tgctgataca
    31021 aaccttcttg cgacggacga ttgtagtaag gggttaccgt caggcagccg acgataccgc
    31081 tgtcattgaa gcgctgcgtc aggctaatgg cttccgcagt agcgttagca ccggtcccgg
    31141 caatcaccgg aatgcgcccg tcagccagct ccagcgtcat catcaccaca tcagcatgtt
    31201 cgtcatgatt taaggtagcg gactcgccag tggtgccaac agaaacgatc gccgaagtac
    31261 cgctggcgac atgataatca atcagttttt tcaagctagc ccgacagaca ttaccttttt
    31321 catccatcgg agtaacaatc gcgacaatac ttcccgtgaa catgggccat cctctgtgca
    31381 aacaagtgtc tcaatggtac gtttggtatg gcattaaaag caagcagaca gaaccgttct
    31441 gattgttgta tgcatgtttt ttttatgctt tccttaagaa caactcaccc cttgaaggaa
    31501 taaccagttt gacactgtca tcgcaacatt atctggtgat cactgcgttg ggtgccgatc
    31561 gccctggaat agtgaacacc atcacccgtc atgtcagtag ttgcggctgt aatattgaag
    31621 acagtcgcct ggcgatgctg ggagaagagt tcacgtttat catgctgctt tccggttcat
    31681 ggaatgccat tactctgatt gaatcaacgt taccgttgaa aggtgccgaa ctggatcttt
    31741 taatcgtgat gaagcgcacg acggcgcgtc cgcgtccgcc aatgccagca tctgtctggg
    31801 ttcaggtcga tgtggcagac tccccgcatt taattgaacg cttcacagca cttttcgacg
    31861 cgcatcatat gaacattgcg gagctggtgt cgcgcacgca acctgctgaa aatgaacggg
    31921 ctgcgcagtt gcatattcag ataactgccc acagccccgc atctgcggac gcagcaaata
    31981 ttgagcaagc gttcaaagcc ctatgtacag aactcaatgc acaaggcagt attaacgtcg
    32041 tcaattattc ccaacatgat gaacaggatg gagttaagta atgaatccac tgaaagccgg
    32101 tgatatcgca ccgaaattta gcttgccgga tcaagacgga gaacaagtta atttgaccga
    32161 cttccaggga cagcgtgttc tggtttattt ctacccgaaa gccatgaccc ccggctgtac
    32221 cgtacaggcc tgcggcttac gcgataacat ggatgagttg aaaaaagcgg gcgttgatgt
    32281 gctgggtatc agcaccgata aacccgaaaa actctcccgt tttgcggaaa aagagctgct
    32341 taactttacg ctcctgtctg atgaggacca ccaggtgtgc gaacaattcg gcgtctgggg
    32401 tgaaaagtcc ttcatgggca aaacctacga tggtattcat cgcatcagct tcctgattga
    32461 cgctgatggc aaaatcgaac atgtttttga cgatttcaaa accagcaatc accacgacgt
    32521 tgtgctgaac tggctgaaag aacacgcctg attactttgc tccattccgt gctggctgcg
    32581 cttgcggtca gcacacctca cttctcgtga tcaagatcac attctcgctt tcccctgcga
    32641 cacgggtgtc gaatccattt attgctgaac gttaatgacc atcatttttg taccgttcag
    32701 aatccagtta acacataaat tattgaatat attaaattaa tcagactggc atcctttatg
    32761 caatatgaaa tgcaatgttt catatcattt tcaaggagcc gacatgaacc gctttgtggt
    32821 ggccgaacca ctgtggtgta caggatgtaa tacctgtctc gctgcctgtt cggacgtgca
    32881 taaaacgcaa ggtttacagc aacacccgcg cctggccctg gcgaagacgt caacactcac
    32941 tgcccctgtc gtgtgtcatc actgtgagga agccccttgc ctgcaggtct gcccggtcaa
    33001 tgccatctcc cagagggacg atgcgatcca actcaacgaa agcctctgta ttggctgcaa
    33061 gctttgcgcc gtggtctgcc catttggcgc aatcagcgct tcaggaagcc gtccggtgaa
    33121 tgcccctgcg caatatgttt ttcaggctga gggctcactc aaagacggcg aagaaaacgc
    33181 gccaacccaa catgctttgc tgcgctggga accgggtgtc cagaccgtcg cggtgaaatg
    33241 cgacctgtgt gatttcttgc cagaaggtcc ggcctgcgtt cgcgcttgtc cgaatcaggc
    33301 gttacggctg atcaccgacg atagcctgca acgtcagatg aaagaaaaac agcgccttgc
    33361 cgcaagctgg tttgccaatg gcggggagga tcccctttcc ctcactcagg agcaacgcta
    33421 atggatgccc tgcaattatt aacctggtcg ctgatcctct atctgtttgc cagtctggct
    33481 tcgctatttt tactcggtct ggacagactg gctattaagc tttccggcat cacatcgctg
    33541 gtgggcggcg tgattggcat catcagcgga attacgcaat tacatgcagg cgtaacttta
    33601 gccgcccgtt ttgccacacc ttttgaattt gccgatttaa ccctgcgaat ggatagcctc
    33661 tcggcattta tggtgctggt tatctccttg ctggtggtgg tttgttcgct ctattcattg
    33721 acttatatgc gcgaatacga gggtaaaggc gcggcggcga tgggcttctt tatgaatctt
    33781 ttcatcgcat cgatggttgc cctgctggtg atggacaacg ctttttggtt catcgtgctg
    33841 tttgaaatga tgtcgctgtc ttcctggttt ctggtcattg ccaggcagga taaaacgtcg
    33901 atcaacgctg gcatgctcta cttttttatc gcccacgccg gatcggtgct gattatgatc
    33961 gccttcttgc tgatggggcg cgaaagcggc agcctcgatt ttgccagttt ccgcacgctt
    34021 tcactttctc cggggctggc gtcggcggtg ttcctgctgg cctttttcgg ttttggcgcg
    34081 aaagccggga tgatgccgtt gcacagctgg ttgccgcgcg ctcaccctgc cgcaccatcg
    34141 cacgcttcgg cgttgatgtc tggcgtaatg gtcaaaatcg gtattttcgg catccttaaa
    34201 gtagcgatgg atctgctggc gcaaacggat ttgccgctgt ggtggggcat tctggtgatg
    34261 gcgatcggcg caatctccgc gctcctgggc gtgctatatg cgctggcgga acaggatatc
    34321 aaacggctgc tggcctggag taccgtcgaa aacgtcggca ttattttgct ggcggtcggt
    34381 gtggcgatgg tcggtctgtc actgcacgac ccgctgctca ccgttgttgg actgctcggc
    34441 gcgctgtttc atctgctcaa ccatgcgctg ttcaaagggc tgctgtttct cggcgcgggc
    34501 gcaattattt cgcgtttgca tacccacgac atggaaaaaa tgggggcact ggcgaaacgg
    34561 atgccgtgga cagccgcagc atgcctgatt ggttgcctcg cgatatcagc cattcctccg
    34621 ctgaatggtt ttatcagcga atggtacacc tggcagtcgc tgttctcact aagtcgtgtg
    34681 gaagccgtag cgctacaact tgcgggtcct attgctatgg tgatgctggc agtcactggt
    34741 gggctggcag taatgtgctt cgtcaaaatg tacggcatta ctttctgtgg tgcgccgcgc
    34801 agtacacacg ctgaagaggc acaggacgtg ccaaatacga tgatcgtcgc catgctactg
    34861 ctcgcggcac tctgcgtatt cattgcgctt agtgccagtt ggctggcacc gaagataatg
    34921 cacattgccc atgcgtttac caatacccct cccgtcactg tcgccagcgg aatagcactt
    34981 gtacccggca cgtttcatac acgggtcact ccctcattac tgttgctgtt actactggcg
    35041 atgcctttgc tgcctggcct ttactggctg tggtgtcgtt cgcgccgcgc agcgtttcgt
    35101 cgcacaggag atgcctgggc atgcggctac ggctgggata atgcgatggc cccgtcaggc
    35161 aatggcgtga tgcagccgct gcgtgtggtc ttttgtgcgc tatttcgtct acgacaacag
    35221 ctcgacccta cgctgaggct gaacaaaggt cttgcgcacg tcaccgccag ggctcagagc
    35281 acagaaccct tctgggatga gcgggtgatc cgccccatcg tgagcgccac ccaacggctg
    35341 gccaaagaaa tacagcatct gcaaagcggc gactttcgtc tctattgcct gtatgtggtc
    35401 gccgcactgg ttgtgctgct aatcgctatt gccgtctaag gaaatcacca tgagacaaac
    35461 tctttgcgac ggatatctga tcatttttgc gttagcacag gccgtgattc tgctggcgct
    35521 aaccccgctt tttacgggga tttcccggca gatacgcgcg cgtatgcact cccgtcgcgg
    35581 accggggatc tggcaggatt atcgcgatat ccacaaactg tttaaacgcc aggaagttgc
    35641 gccgacatct tcaggtctga tgttccgcct gatgccgtgg gtattaatca gcagcatgct
    35701 ggtgctggcg atggccctac cactatttat tactgtttcc ccttttgcgg gcggcggcga
    35761 tctgatcacc cttatctatc ttcttgccct atttcgtttt ttctttgctc tttccgggct
    35821 ggataccgga agcccctttg cgggaatcgg tgccagtcgc gagttaacgc tcggcattct
    35881 ggtcgaaccc atgctcattc tctcactgct ggtattggcg ctgatagcgg attccacgca
    35941 tatcgagatg atcagcaaga cgctggcgac gggctggaac tcgccgctaa ccaccgtact
    36001 ggcgttactg gcctgtggtt ttgcctgctt cattgagatg ggaaaaattc cctttgatgt
    36061 tgctgaagca gaacaggaat tacaggaagg cccgctgacc gaatattccg gtgccgggct
    36121 ggcgctggcg aagttggggc tggggctgaa acaggtcgtg atggcatcac tgtttgtggc
    36181 cctgtttctg ccctttgggc gcgcgcaaga gctttctctc acctgcctgc tgacttcact
    36241 tgtcgttacg ctgctcaagg ttttgctgat ttttgttctg gcctctatcg cagaaaacac
    36301 gctggcacgc gggcgatttt tactcattca ccatgtgacc tggcttggct tcagccttgc
    36361 tgcgcttgcc tgggtcttct ggttaaccgg tctgtaagga gcactaacgg aatatggaaa
    36421 atcttgctct gacgacgtta ttgctgcctt ttatcggcgc actggtcgtt tcgttttcgc
    36481 cacaacgtcg ggccgccgaa tggggggttt tgttcgccgc gctgaccacg ctgtgcatgt
    36541 tgtcactgat ctccgcgttt tatcaggccg ataaagttgc cgtcacgttg acgttggtca
    36601 acgtggggga tgtggcgttg tttggcctgg tcattgatcg cgtgagtacg ctgattctgt
    36661 ttgtggtggt gttcctcggt ttgctggtca cgatctactc cacgggttat ctgacggata
    36721 aaaatcgcga acacctgcat aacggcacga atcgttatta cgcatttttg ctggttttta
    36781 tcggcgcgat ggcgggactg gtactctcct cgacgctgct cggtcagttg ttgttttttg
    36841 aaattacggg cggctgctcc tgggcgttga tcagttatta ccagagcgat aaagcgcagc
    36901 gttcagcact aaaagcgtta cttatcactc atatcggttc gctggggttg tatcttgccg
    36961 ccgccacgct gtttttgcag accggaacgt ttgcgcttag cgcgatgagc gagttacacg
    37021 gcgacgcacg ttatctggtt tatggcggca tcctgtttgc cgcgtggggg aaatcggccc
    37081 agctaccgat gcaagcgtgg ctaccggatg caatggaagc gccaacaccg atcagcgcct
    37141 atctccacgc cgcatcgatg gtgaaagtgg gcgtttacat ttttgcccgt gccattatcg
    37201 acggcggcaa tatcccgcat gtgattggcg gcgttggcat ggttatggca ctggtcacca
    37261 ttctttacgg cttcctgatg tatttgccac agcaggatat gaagcggttg ctggcctggt
    37321 cgaccatcac tcaacttggc tggatgtttt tcggcttgtc gctctccatc ttcggctcgc
    37381 ggctggcgct ggagggcagc atcgcctaca tcgtcaacca cgcgttcgct aaaagcctat
    37441 ttttccttgt agcaggtgcg ctgagttaca gctgcggcac gcgcttgttg ccgcgtctgc
    37501 gtggcgtatt gcacaccctg ccgttgccag gcgtgggttt ctgcgtagcc gcgctggcga
    37561 ttactggcgt accgccgttc aacggcttct tcagtaaatt cccgctgttt gccgccggtt
    37621 tttcgttgtc agtggagtac tggatcctgc tgcccgccat gattctgctg atgtttgaat
    37681 cggtcgccag tttcgcctgg tttattcgct ggtttggtcg cgtcgtgcct ggcaaaccga
    37741 gcgaggccgt cgccgatgcc gcaccgctgc caggatcaat gcgcctggtg ttgattgtac
    37801 tgattgtgat gtcgctgatt tccagcgtaa tcgccgcgac ctggttgcag taaggagatg
    37861 atgaatgacc ggttctatga tcgtaaataa tctggcggga ctgatgatgc tgacatcgct
    37921 gtttgtgatt agcgtcaaaa gctatcgcct gtcatgcgga ttttacgcct gccagtcgct
    37981 ggtgctggtg tctattttcg ccaccctctc gtgcctgttc gtcgcagagc aactgctgat
    38041 ctggtccgcc agcgccttta tcaccaaagt gctgctggta ccgttaatca tgatttacgc
    38101 tgcacgaaat attccccaga acatcccgga aaaagcgtta ttcggtccgg ctatgatggc
    38161 attgctcgcg gcattaattg tcctgctttg cgcatttgtc gttcagcccg tgaagctacc
    38221 gatggctacc gggctgaaac cggcgctggc ggtggcgtta ggtcattttc tgcttggcct
    38281 gctgtgcatt gtcagccagc gcaatatcct gcggcaaatt tttggttact gcctgatgga
    38341 aaacggctcc catctggtgc tggcgcttct tgcctggcgt gcaccggaac tggtggaaat
    38401 tggtatcgct accgacgcca tcttcgccgt cattgtgatg gtgttactgg caagaaaaat
    38461 atggcgtacc cacggcacgc tggacgtgaa caacttgacc gcgctgaagg gataatgaga
    38521 tgagttattc tgtgatgttc gctttactcc tgctcacgcc gctgcttttt tcgctgctct
    38581 gttttgcctg ccggaaatgg ggacactctg cgactcgcac ggtgacagta ctacatagct
    38641 tagggatcac actgctgctg attctgacac tgtgggtggt ccaaactgcc gctgatgcgg
    38701 gagaaatatt cgctgcggga ctgtggcttc atattgatgg tctgggcggt ttgttcctcg
    38761 ccattcttgg tgtgattggc tttctcaccg gtgtttactc gattggctac atgcgtcatg
    38821 aagtggcaca cggcgagctt tcacccgtta cgctgtgcga ttactacggt ttcttccatc
    38881 tgtttttgtt caccatgctg ctggttgtta ccagcaataa cctgattgtg atgtgggcgg
    38941 cgatcgaagc caccacctta agctcggcgt ttctggtagg catttacggt cagcgttcat
    39001 cgctggaagc tgcatggaag tacatcatta tttgtactgt tggtgtcgct tttggtctgt
    39061 tcggtaccgt gctggtatac gccaacgccg ccagcgttat gccgcaggca gaaatggcga
    39121 tattctggag cgaggttctt aagcaatcgt ccttgcttga cccaacatta atgctgttgg
    39181 cctttgtgtt tgtgctaatt ggctttggca ccaaaaccgg gctattcccc atgcacgcct
    39241 ggctgccaga tgctcacagt gaagcgccga gtccggtcag cgccctgctc tccgccgtat
    39301 tgctgaactg cgcgctattg gtgctgattc gctattacat cattatttgc caggccatcg
    39361 gcagcgattt ccccaaccgg ttgttgctca tcttcggcat gttgtcggtt gccgtggcgg
    39421 catttttcat tctggtacag cgggacatta agcgtctgct ggcgtactcc agcgtggaga
    39481 acatgggact ggtcgcggtg gcgttaggca ttggcgggcc gctgggaatt tttgccgcgc
    39541 tgctgcacac cttaaaccac agtctggcaa aaacgctgct gttctgcggt tccggcaatg
    39601 tactgctcaa gtacggcacg cgcgatctca acgtcgtctg cggaatgctc aaaatcatgc
    39661 catttaccgc cgtgctgttt ggcggcggtg cgctggcgct ggccgggatg ccgcccttca
    39721 acatttttct tagcgaattt atgaccgtta ccgccggact ggcgcgtaat cacctgctga
    39781 ttatcgtcct gctgttattg ctgttaacgc tggtgctggc gggcctggta cggatggctg
    39841 cgcgggtgtt aatggcgaaa ccgccgcagg ccgttaaccg gggtgaactt ggctggttga
    39901 ccacctcgcc aatggtgatt ctgctggtca tgatgctggc gatgggaacg catattccac
    39961 aacctgtcat caggatcctg gcgggcgctt ccactatagt cctctcaggg acgcacgacc
    40021 tgcctgcaca acgtagcacc tggcatgatt ttttgccttc aggcaccgca tctgtttcgg
    40081 agaaacacag tgaacgttaa ttcatcgtca aatcgtggcg aagcgattct cgccgccctg
    40141 aaaacgcagt tccccggcgc ggtgctggat gaagagcgac aaacgcctga acaggtcacc
    40201 attacggtga aaatcaatct gctgcctgac gttgtgcatt atctttatta tcaacatgat
    40261 ggctggcttc cggtcctgtt tggcaacgac gagcggacac ttaacggtca ttacgcggtt
    40321 tattatgccc tttctatgga aggggccgaa aaatgctgga tcgtggtgaa ggcactggtc
    40381 gatgccgaca gtcgggagtt tccgtcagtc acaccgcgcg tccctgccgc ggtctggggc
    40441 gagcgagaaa ttcgcgatat gtacgggttg attccggttg gccagccgga tcagcgtcgg
    40501 ctggtgttgc ccgatgactg gccggaagat atgcatccgc tgcgcaaaga cgcgatggat
    40561 tatcgactgc gcccagaacc gacgactgat accgaaacgt atccgtttat caacgagggc
    40621 aacagcgatg cgcgggtgat ccctgtcggc ccgctgcata tcacctccga tgaaccaggt
    40681 cacttccgct tgtttgtgga tggcgagcaa attgtcgatg ctgattaccg cctgttttat
    40741 gtccatcgcg gcatggagaa actggcagaa acgcggatgg gctacaacga agtgaccttc
    40801 ttatccgacc gcgtgtgtgg gatttgcggt tttgcccaca gtgtggccta taccaactcg
    40861 gttgaaaatg cactggggat tgaggtgccg caacgagcgc atactattcg ctcgattctg
    40921 ctggaagtcg aacggctgca tagtcatttg ctcaaccttg gcctctcctg ccattttgtt
    40981 ggttttgata ccggctttat gcaatttttc cgcgtgcggg aaaagtcgat gacgatggcg
    41041 gaattgctga ccgggtcgcg taaaacctac ggtctgaatc tgattggtgg tgttcgccgc
    41101 gatattctca aagagcaacg tctgcaaacg ctgaaactgg tgcgcgagat gcgcgccgac
    41161 gtgtcggagc tggtagagat gttgcttgcc acgccgaata tggaacaacg cactcagggc
    41221 attggcattc tcgaccgaca aatcgcccgt gattatagcc ccgtagggcc gctgatccgc
    41281 ggcagtggct ttgcccgtga tttgcgcttt gatcacccct acgccgacta cggcaatatt
    41341 cccaaaacgc tgtttacctt taccggcggc gatgtcttct cccgcgtgat ggtccgtgtc
    41401 aaagagacgt ttgattcgct ggcaatgctg gaatttgccc tcgacaacat gccagatacc
    41461 ccactgctga ccgaaggctt tagctataaa cctcacgcat tcgcgctggg ctttgttgaa
    41521 gcgccacgtg gtgaagacgt gcactggagc atgctcggtg ataaccaaaa attgttccgc
    41581 tggcgctgtc gtgccgccac ctacgccaac tggccagtgc tgcgttacat gctgcgcggc
    41641 aataccgttt ctgacgcacc gctgattatc ggtagccttg atccctgtta ctcctgtacc
    41701 gaccgtgtga cgctggttga tgtgcgcaag cgccagtcaa aaaccgtgcc gtataaagag
    41761 atcgaacgct acggcattga tcgtaaccgt tcgccgctga agtaaggaca gaaaatgctg
    41821 aagttactga aaactattat gcgcgccgga accgcgacgg tgaaatatcc cttcgcgcca
    41881 ctggaggtca gcccaggctt tcgcgggaaa ccggacctga tgcccagcca atgtattgcc
    41941 tgcggtgcct gcgcctgtgc ttgtccggca aatgcgctga ctatccagac cgacgaccaa
    42001 caaaatacgc gcacctggca gctctatctg gggcgttgta tttactgcgg acgttgtgaa
    42061 gaagtgtgcc cgaccagagc cattcagctt accaataact ttgaactgac cgtcaccaat
    42121 aaagccgatc tctatacccg cgcgacgttt catctacaac gttgcagtcg ttgcgaacgc
    42181 ccatttgccc cgcaaaaaac cgtcgcactg gctgcagaac tgttggcaca gcaacaaaat
    42241 gcgccacaaa accgcgaaat gttgtgggcg caagcgagca tctgcccgga atgcaaacaa
    42301 cgcgcgacgc tgatcaacga cgatacagat gtaccgctgg tggctaagga gcagctatga
    42361 gtccagtgct tacgcaacat gtcagccagc ccataacgct ggacgagcaa acgcaaaaga
    42421 tgaagcagca tttgctacag gatatccgtc gctcggctta cgtttatcgc gtcgattgcg
    42481 gcggctgcaa cgcctgcgaa atcgaaattt ttgccgccat cacacccgta ttcgacgcag
    42541 aacgttttgg cattaaggtt gtttcatcac cgcgtcacgc cgatattttg ttatttactg
    42601 gcgcagtcac ccgggcgatg cgtatgcctg cacttcgggc atatgagtct gcccccgatc
    42661 ataaaatctg tgtttcctac ggcgcgtgcg gtgtcggcgg cggtattttc cacgatcttt
    42721 acagcgtctg gggcggcagc gacaccattg tccccattga tgtttggatc cccggctgcc
    42781 cgccaacacc ggccgccacc attcacggtt tcgccgtggc gctcggtttg ctgcaacaga
    42841 agattcacgc ggtggattat cgcgatccca ccggggtgac catgcaaccg ctgtggccgc
    42901 agatcccgcc atcacagcgt atcgccattg agcgagaagc gaggcggctg gcgggctatc
    42961 gtcaagggcg agaaatttgc gatcggctcc tgcgccattt aagcgacgat cctacaggaa
    43021 atcgggttaa cacctggttg cgcgaagctg acgatccacg tctcaatagt atcgttcagc
    43081 aactctttcg cgttctccgg gggttacatg gctgaggagt gcagggaaat tgttttctgg
    43141 acgctgcgaa aaaaatttat cgccagtagc gacgagatgc cggaacacag ctcccaggta
    43201 atgtattact cgttggctat cggtcatcac gttggcgtga ttgattgttt gaatgtcgcc
    43261 ttccgctgcc cacagacgga atacgaagat tggcttgcac aggtcgaaga ggagcaagcc
    43321 cgacgtaaga tgctgggggt gatgactttt ggtgagattg ttattgacgc cagccacacc
    43381 gccctgttga cccgggcatt cgcgccactg gcagatgacg cgacgtcggc gtggcaggcg
    43441 cgtagcattc aattcattca tctgttggat gaaattgtgc aggaaccggt catctatctg
    43501 atggccagaa aaattgcgtg agaaggattt ctcattaata aggactgttg atggctatgt
    43561 cagacgaggc gatgtttgcc ccgccgcaag gaataacaat tgaagcggta aacggaatgc
    43621 tcgcggagcg gttagcacag aaacacggca aggcgtcttt attacgcgcc ttcatcccgc
    43681 tgccgccgcc gttcagcccg gtacaactta ttgaactgca tgttctcaaa agcaacttct
    43741 attaccgcta ccatgatgat ggcagcgatg tgacggcaac aacagagtat cagggtgaga
    43801 tggtcgatta ttcgcgccac gccgtccttc tcggcagtag tggaatggcg gagctacgct
    43861 ttattcgcac ccacggcagt cgttttactc cccaggattg cacactgttt aactggctgg
    43921 cacacataat cactccggtt ctgcaatcat ggctcaatga tgaagaacag caggtggcgc
    43981 tgcgtttgct ggagaaagat cgcgatcatc atcgggtact ggtggatatc actaatgcag
    44041 tgttgtcaca tcttgatctc gacgatctga tcgctgacgt cgctcgtgag atccatcatt
    44101 ttttcggtct ggcttcagtc agtatggtac tgggcgatca tcgaaagaac gagaagttca
    44161 gcctgtggtg cagcgatctt tctgcctcac attgtgcgtg tctgccacgc tgtatgcctg
    44221 gcgaaagtgt attgctgaca caaacgctac aaacccgaca accgaccttg acgcactgtg
    44281 cagacgatct gtttctctgg caacgcgacc cgttattaca cttacttgca tctaacggct
    44341 gcgaatctgc gctccttata ccgctcacct ttggcaacca tacaccgggt gcattgttgc
    44401 tggcgcatac ctcttccact ctctttagtg aggaaaactg ccagctacta caacatattg
    44461 ccgatcgcat cgctattgcc gttggcaatg ccgatgcctg gcgcagcatg accgatttgc
    44521 aggaaagctt gcagcaagaa aaccaccagc ttagcgagca gctcctttcg aatctgggcg
    44581 tcggtgacat tatctatcaa agccaggcaa tggaagacct gctccagcag gtagatattg
    44641 tggcgaagag cgacagtacg gtgttgattt gtggtgaaac cggaaccggc aaagaggtga
    44701 tcgccagagc gatccatcaa cttagcccac gacgcgacaa gccactggtc aaaatcaact
    44761 gcgctgccat ccccgccagt cttctggaaa gtgagttatt cggtcatgac aaaggggcat
    44821 ttactggtgc gattaatacc catcgtggtc gttttgaaat tgccgatggc ggcacgttgt
    44881 ttctcgatga aattggcgat ctgccgttag aacttcagcc taaactgctg cgcgtattgc
    44941 aggaacggga gattgagcgt ctcggcggga gtagaacgat cccggtaaat gtcagagtca
    45001 ttgccgccac caaccgtgat ttgtggcaaa tggttgaaga tcgccagttt cgcagcgatc
    45061 tcttttatcg cctgaatgtc ttcccactgg aactgccgcc actgcgcgac cgtccggaag
    45121 atatccctct tttagcaaag catttcacgc aaaaaatggc gcgccatatg aatcgcgcaa
    45181 ttgacgccat cccgaccgag gcgctacgcc agttgatgtc gtgggactgg ccgggcaacg
    45241 tgcgcgagct ggaaaacgtg attgagcgag cggtactact gactcgcggt aacagtctga
    45301 atttacatct taatgtccga caaagccgtt tactgccgac gctaaatgaa gattcagcgc
    45361 ttcgcagttc aatggcgcag ttactgcacc cgacgacgcc agagaatgac gaagaagaac
    45421 gtcagcgcat tgttcaggta ttgcgagaaa ccaatggcat tgttgccggg ccccgtggcg
    45481 cggcgacacg attagggatg aagcgcacca cgctgctgtc acgaatgcag cgtctgggga
    45541 tctcggttcg cgaggtgttg taatctgttt ttgcaggagt atgcatgaga aacaaactct
    45601 ctttcgactt gcagttgagc gccagaaaag cggcaatcgc tgaacggatt gccgcccata
    45661 aaattacccg cagcaaagtg tcggtctttt taatggcgat gtccgcaggc gtgtttatgg
    45721 cgatcggatt tactttttac cttaccgtta tcgccgatgc cccgtcttca caggcattaa
    45781 cccatctggt gggcggcctt tgctttacac tcggctttat tttgctggcg gtttgcggca
    45841 ccagcctgtt cacctcgtcg gtaatgacgg tgatggcaaa aagtcggggc gttattagct
    45901 ggcgaacatg gctgattaat gcacttctgg tggcctgcgg taatctggca ggtattgcct
    45961 gtttcagttt gttaatctgg ttttccgggc tggtgatgag tgaaaacgcg atgtggggag
    46021 tcgcggtttt acactgcgcc gagggcaaaa tgcatcatac atttactgaa tcagtcagcc
    46081 tcggcattat gtgcaatgtg atggtttgcc tggcgctgtg gatgagttat tgcggacgtt
    46141 cgttatgcga caaaatcgtc gccatgattt tgcccatcac cctgtttgtc gccagtggct
    46201 ttgagcactg tatcgccaat ttatttgtga ttccgttcgc cattgccatt cgccatttcg
    46261 cccctacctc cttctggcaa ctggcgcaca gtagcgcaga ccattttccg gcactgacgg
    46321 tcagccattt tattaccgcc aatctgctcc cggtgatgct gggtaatatt atcggcggtg
    46381 cagtgctggt gagtatttgt tatcgggcta tttatttacg tcaggaaccc taaaaatcag
    46441 cccggcgaaa cagttcgtcg ggctgaagat tattcttgcg cgatttgccc atcgggccag
    46501 gcgtgaatca cggctttgat cagcgtcgcc aatggaatgg cgaagaatac gccccagaat
    46561 ccccacaaac caccgaagat caccaccgat aaaataatca ccagcggatg caggttaacc
    46621 gcttcggaga acaacaccgg cactagcagg ttgccgtcca gcgcctgaat gatcagatac
    46681 accgcgaagc agctccagaa ttccgtgcca gcaccaaact ggaatagcgc cacgccaatc
    46741 accggaatgg tcaccacaaa tgcgccaatg tacggaataa gaaccgagaa gccgaccagc
    46801 accgccagca gcagcgaata gttcagcccg aagagtaaga accccagcca ggtggcgatc
    46861 cccaccacga tcatctccag cactttgccg cggatatagt tggtgatttg ttgattcatc
    46921 tccttccaca cctgtcctgc cagtccgcgg ttacgcggta gcacccgacg aacggcgttc
    46981 agcatctgct ctttgtcttt cagcaggaag aagaccatca atggcaccag caccagatag
    47041 acagctatgg tgagcaaacc gaccagcgag gcgagggaaa ttttcaccac cgaatcgccc
    47101 atggtcagca tccgactgcg catattttcg gccattgcat caataatgcc cgcgtccatt
    47161 aacgccggat agcggcgcgg caacgtggcg gcaaagtcag aaagcttatt gagcatcccc
    47221 ggcatatcgc gaattaagta gatgccctgc tgccaggcga taggcaatac cacgaacgcc
    47281 atcagtagca atataccgac gaaaaccacc aatacaatcg acgtcgccca gcggcgggag
    47341 cagccaatag attgcaggcg cacggttggc cattccagca aataggccag cacaatagcc
    47401 accagcaacg gagcaagcag gccactaaag aaaaagataa tgccaaatcc ggcaactaaa
    47461 ataaccagca aggcaatcgc ttccgggtcg ctaaaacggc ggcgatacca ttgcatcaac
    47521 atttcgagca taaagacctt ccctgaacct caagagcggg attgcgatcc gcaattgtat
    47581 cgaaatgtca caaaaaagac ttcgcttttt atgacggatt caggaaactg aaaagtcatt
    47641 tgagtgggct aatcttcgcc gttacactca aaggcggcgc ggtgggaacg atatttcaca
    47701 gtatcggtca aatgactatc ttcagaaata caggatagag gttatgttca ggcagttgaa
    47761 aaaaaacctg gttgcaaccc tcattgctgc tatgaccatt ggtcaggtag ccccggcgtt
    47821 tgccgacagc gcagacacct tgccggatat gggaacctcc gcaggaagca cgctttccat
    47881 tggtcaggaa atgcagatgg gcgactatta tgtccgccag ctacgcggca gcgcgccgtt
    47941 aattaatgac ccgctgttaa cgcaatatat taattcgctg ggtatgcgtc tggtttcgca
    48001 tgccaattcg gttaagacac cgtttcattt ctttctgatc aacaacgacg aaattaacgc
    48061 ctttgctttc tttggcggca acgtggtgct gcactctgcc ctgttccgtt attccgataa
    48121 cgaaagtcaa ctggcttcag ttatggcgca cgaaatctcc cacgtcaccc aacgtcacct
    48181 ggcgcgagcg atggaagatc aacagcgcag cgcgccgctg acctgggtcg gcgcgttagg
    48241 ttctatttta ctggcgatgg ccagtccgca ggcggggatg gcagcgctga ccggtacact
    48301 ggcgggaacg cgccagggga tgatcagttt cacccagcaa aatgaacagg aagcggatcg
    48361 cattggtatt caggtgctgc aacgctcagg attcgatccg caggcgatgc cgaccttcct
    48421 cgaaaaattg ctcgatcagg cgcgttactc ctcgcgtccg ccggaaattt tattgactca
    48481 cccgttgccg gaaagtcgtc tggcagatgc ccgcaaccgt gctaatcaga tgcgcccgat
    48541 ggtggtgcag tcgtcggagg atttctatct ggcgaaagcg cgcacactgg ggatgtataa
    48601 ttccggacgt aatcagctca ccagtgattt gctggatgaa tgggcgaaag gaaacgttcg
    48661 tcagcaacga gcggcgcaat atggtcgtgc tctacaggcg atggaagcca ataaatacga
    48721 tgaggcgcgt aaaacgctgc aaccgttact ggcggcagaa cctggtaacg catggtatct
    48781 cgatctggct accgatatcg atcttgggca aaacaaagcc aatgaggcaa tcaatcgcct
    48841 gaaaaatgcc cgtgatttgc gtaccaatcc ggtgttgcag ctcaacctgg cgaacgctta
    48901 tctgcaaggc ggtcaaccac aagaagcggc caatattctg aatcgctaca cttttaataa
    48961 taaagatgac agcaacggct gggatttact ggcacaggcg gaagccgcgc taaataaccg
    49021 cgatcaggaa ctggctgcgc gagcagaagg ttatgcgctc gccgggcgac tcgatcaggc
    49081 catttccttg ttgagtagcg ccagttcgca ggtgaaatta ggcagcctgc aacaagcgcg
    49141 ttacgatgcg cgcatcgacc agttgcgcca gctgcaggaa cgctttaagc cttataccaa
    49201 gatgtaattc gcattaaagg aagaacaatg accaaacagg taaaaatcta ccataaccca
    49261 cgctgttcaa agagccggga aacgctgagc ctgctgaaag aaaacggcgt ggagccagaa
    49321 gtggtgctct accttgagac acccgccgat gcggcaacgc tgcgtgattt gctgaaaatg
    49381 ctgggaatga atagcgctcg tgaattgatg cgccagaaag aggatcttta taaagaactg
    49441 aacctggctg acagttcgct tagcgaaggg gcgctgattc aggcaatggt ggataatcca
    49501 aagctaatgg agcgcccgat tgtggtcgcg aatggcaaag cgcggattgg tcgtccaccg
    49561 gagctggtac tggaaatcgt gggttaagaa gtgctccatc gctagttgaa gcacattgcc
    49621 ggatgcgacg cttgccgcgt cttatccggc cgacgaatac tatgggtgca tatccgacaa
    49681 taaacgtctt gtctacagtt tcagaatttc tttcacaaac ggaatggtca gcttacgttg
    49741 cgcggtaatc gacgcacgat ccagctgatc cagcgtcata aataacgtgc gcatttctct
    49801 gtcgagccgc ttcagcaaga aacgccccac atcttccggc agttcaaaac cacgcaaacg
    49861 cgcgcgtaac tgtagcgcct gcaacttatc ttcatcagaa agtggctgca atttgtagat
    49921 ctgcccccag tcgagtcgcg acgcgagatc cggtaatccc agattcaact gccgcggtgg
    49981 acgatcgccg gtgatcaaca accgtgtttt gcccgattcc agaattcgat tgtagagatc
    50041 gaaaatcgcc atctcccaca actcatcgcc tgcaatacac tcaatgttgt cgatacagac
    50101 cagcgacaaa tgctccatac cgtcgagcac ttccggaaca aaccaggtgc gtttatccag
    50161 cgggacatag cccaccgcat cgccacgctg cgacaattcc gcgcaagccg cgtgcagcag
    50221 atggctgcgc cccgcgcctt cgcgtgccca gagatagatg taaccgctat gttcctgacg
    50281 cagcacgttt tgcagcgcgg ccagtaaaga ggagttatcc cccggccaga aacttgcaaa
    50341 ggtttcgtcg tcaggaagat aaagtggcaa agagagctgt gccggtgtgt tcagagatac
    50401 ctcaaccagg atttcacaaa atcgcgagaa gtttaccaca gaatcccatg atgtttgaac
    50461 cgggcagcaa cactgcccgg tcggtacatt atttgtctgt tatatccgcg tcttctgcgt
    50521 ccagcaccac ttcttcaggg cgcagcatac taatcagttt gaagatcaaa cttaagccga
    50581 taccgacgat ggtcgccagc gccatacctt tcagctccgc cgcgccaatg tttaccttcg
    50641 cgccactgac gccgatgatc aaaataacgg aagtcaggat caggttctgt gctttgttgt
    50701 aatccacttt cgattcgatc aacacacgaa taccggaagc accgatgaca ccgtaaagca
    50761 gcagcgaaac gccgcccatc accggcaatg gaatcatctg gatagcagca gccagtttac
    50821 cgacgcagga aagcaggata gcgaaaatcg ccgccccgcc gataacccag gtactgtaaa
    50881 cacgggtgat cgccatcacg ccaatgtttt ctccgtaagt ggtgtttggc gtggagccaa
    50941 agaagccgga gatcacggtc gacaagccgt tagcaaacat cgaacggtgc agacctggat
    51001 cgcgcagcag atcttttttg acgatattag ccgttaccac caggtgccct acgtgttcgg
    51061 caataaccac taacgccgct ggcagaatag tcagaatggc aaaccactcg aagcgcggcg
    51121 tatagagggt cggcagcgca aaccagtgag cattaataat cggcgtggta tcgacaattc
    51181 ccattgcgaa agagagcgcg tagcccacca gcacgccaat taaaatcggg ataattgcca
    51241 ggaaaccacg aaacagcacg gaacctaaaa ccgtgactgc caaggtggta atggagatga
    51301 tgatggtttt ggagtctggc gtttgccctt cagccgggag taaacctgcc ataccggcag
    51361 ctacgcccgc cagctccaga ccgatgacgg caacgattgc gcccattgcc gcaggtggaa
    51421 acagcacgtc cagccagccg gtccccgctt tcttcacgat aaaagaaacc aggcagaaca
    51481 gcacgccgca cataataaag ccgcccagcg cgacttcata ccctaacggc aacagtaaca
    51541 ataccggtga aataaaggca aagctggaac caagataagc cgggattttc cctttacaga
    51601 tgaagagata cagcagcgtt cctataccgt taaataacag tacagtcgcc gggttaatat
    51661 gaaataagac gggcaccagg acggttgcac caaacatggc gaacaaatgt tgcaaactaa
    51721 gcgggattgt ctgtaaaagt ggcggtcttt cactcacccc gatagcacgg cgcgtcatag
    51781 aattatcctc tgtattatgt gttataggcg ctttactcaa aaaaaagccg actcttaaag
    51841 tcggctttaa ttatttttat tctttatttc gtaccaaaga ttttgtcacc ggcatcgccg
    51901 aggcccggaa taatgtatcc gtgctcgttc agtccctggt caatcgatgc ggtatacagt
    51961 tcgacgtccg ggtgcgcttt ttccagcgca gcgatacctt ctggcgcagc taccagtacc
    52021 agaactttga tgctgctgca gcccgctttt ttcagcaggt cgatggtcgc gataacggaa
    52081 ccaccggttg ccagcattgg gtcaacgatc agcgccatac gctcatcgat gttagaaacc
    52141 agtttctgga agtacggtac cggctccagc gtttcttcat tacggtacat accgacgacg
    52201 ctgatacgcg cgctcggaac gttttccagc acaccgtcca tcatccccag accggcacgt
    52261 agaattggca caacggtaat tttcttacct ttgatctgat cgatttctac cgggccgttc
    52321 cagccttcga tagttacttt ttccgtttcg aggtcggcgg tcgcttcgta agtcagcagg
    52381 ctacccactt cggaagcgag ttcgcgaaag cgcttggtgc tgatatcttg ctcacgcatc
    52441 agtcccagct tgtgtttgac gagtgggtgt ttgacttcca cgatcttcat actctttctc
    52501 ctttgagggg cagccacaaa aaaatcgacg gattatacct cctttcttca aggcggcaat
    52561 attattttcg ttgactttag tcaaaatgat aacggtttga gataaagtta ttttgtattc
    52621 aaatggttat ggaagaagat tattccatcc gaaaacgatc ctttgccctg gtacaagtat
    52681 tcttttgccg cgcgcctggg gaaaagacgt gcaaaaaggt tgtgtaaagc agtctcgcaa
    52741 acgtttgctt tccctgttag aattgcgccg aattttattt ttctaccgca agtaacgcgt
    52801 ggggacccaa gcagtgaccg ataaaacctc tcttagctac aaagatgccg gtgttgatat
    52861 tgacgcgggt aatgctctgg ttggaagaat caaaggcgta gtgaagaaaa cgcgtcgtcc
    52921 ggaagtgatg ggcggtctgg gcggcttcgg tgcgctgtgt gcattgccgc aaaaatatcg
    52981 tgaacccgtg ctggtttccg gcactgacgg cgtaggtacc aagctgcgtc tggcgatgga
    53041 cttaaaacgt cacgacacca ttggtattga tctggtcgcc atgtgcgtta atgacctggt
    53101 ggtgcaaggt gcggaaccgc tgtttttcct cgactattac gcaaccggaa aactggatgt
    53161 tgataccgct tcagcggtga tcagcggcat cgcggaaggt tgtctgcaat cgggctgttc
    53221 actggtgggt ggcgaaacgg cagaaatgcc ggggatgtat cacggtgaag attacgatgt
    53281 cgctggtttc tgcgttggcg tggtagaaaa atcagaaatc attgacggat ctaaagtcag
    53341 cgacggcgat gtgctgattg cactcggctc cagcggtccg cactcgaacg gctattcgct
    53401 ggtgcgcaaa attcttgaag tcagcggttg tgatccgcaa accaccgaac ttgatggtaa
    53461 gccattagcc gatcatctgc tggcaccgac ccgcatttac gtgaagtcag tgctggagtt
    53521 gattgaaaag gtcgatgtgc atgccattgc gcacctgacc ggcggcggct tctgggaaaa
    53581 cattccgcgc gtattgccag ataataccca ggcagtgatt gatgaatctt cctggcagtg
    53641 gccggaagtg ttcaactggc tgcaaacggc aggtaacgtt gagcgccatg aaatgtatcg
    53701 caccttcaac tgcggcgtcg ggatgattat tgcccttcct gctccggaag tggacaaagc
    53761 cctcgccctg ctcaatgcca acggtgaaaa cgcgtggaaa atcggtatca tcaaagcctc
    53821 tgattccgaa caacgcgtgg ttatcgaata atgaatattg tggtgcttat ttccggcagc
    53881 ggaagtaatt tgcaggcaat tattgacgcc tgcaaaacca acaaaattaa aggcaccgta
    53941 cgggcagttt tcagcaataa ggccgacgcg ttcggccttg aacgcgcccg ccaggcgggt
    54001 attgcaacgc atacgctcat cgccagcgcg tttgacagtc gtgaagccta tgaccgggag
    54061 ttgattcatg aaatcgacat gtacgcaccc gatgtggtcg tgctggctgg ttttatgcgc
    54121 attctcagcc cggcgtttgt ctcccattat gccgggcgtt tgctgaacat tcacccttct
    54181 ctgctgccga aatatcccgg attacacacc catcgtcagg cgctggaaaa tggcgatgag
    54241 gagcacggta catcggtgca tttcgtcacc gatgaactgg acggtggccc ggttatttta
    54301 caggcgaaag tcccggtatt tgctggtgat acggaagatg acatcaccgc ccgcgtgcaa
    54361 acccaggaac acgctattta tccactggtg attagctggt ttgccgatgg tcgtctgaaa
    54421 atgcacgaaa acgccgcgtg gctggatggt caacgtctgc cgccgcaggg ctacgctgcc
    54481 gacgagtaat gcccccgtag ttaaagcgcc agctctgccg ctggcgtttt tcaattcacc
    54541 tgtaaatcgc aagctccagc agtttttttc ccccttttct ggcatagttg gacatctgcc
    54601 aatattgctc gccataatat ccaggcagtg tcccgtgaat aaaacggagt aaaagtggta
    54661 atgggtcagg aaaagctata catcgaaaaa gagctcagtt ggttatcgtt caatgaacgc
    54721 gtgcttcagg aagcggcgga caaatctaac ccgctgattg aaaggatgcg tttcctgggg
    54781 atctattcca ataaccttga tgagttctat aaagtccgct tcgctgaact gaagcgacgc
    54841 atcattatta gcgaagaaca aggctccaac tctcattccc gccatttact gggcaaaatt
    54901 cagtcccggg tgctgaaagc cgatcaggaa ttcgacggcc tctacaacga gttgttgctg
    54961 gagatggcgc gcaaccagat cttcctgatt aatgaacgcc agctctccgt caatcaacaa
    55021 aactggctgc gtcattattt taagcagtat ctgcgtcagc acattacgcc gattttaatc
    55081 aatcctgaca ctgatttagt gcagttcctg aaagatgatt acacctatct ggcggtggaa
    55141 attatccgtg gcgataccat ccgttacgcg ctgctggaga tcccatcaga taaagtgccg
    55201 cgctttgtga atttaccgcc agaagcgccg cgtcgacgca agccgatgat tcttctggat
    55261 aacattctgc gttactgcct tgatgatatt ttcaaaggct tctttgatta tgacgcgctg
    55321 aatgcctatt caatgaagat gacccgcgat gccgaatacg atttagtgca tgagatggaa
    55381 gccagcctga tggagttgat gtcttccagt ctcaagcagc gtttaactgc tgagccggtg
    55441 cgttttgttt atcagcgcga tatgcccaat gcgctggttg aagtgttacg cgaaaaactg
    55501 actatttccc gctacgactc catcgtcccc ggcggtcgtt atcataattt taaagacttt
    55561 attaatttcc ccaatgtcgg caaagccaat ctggtgaaca aaccactgcc gcgtttacgc
    55621 cacatttggt ttgataaagc ccagttccgc aatggttttg atgccattcg cgaacgcgat
    55681 gtgttgctct attatcctta tcataccttt gagcatgtgc tggaactgct gcgtcaggct
    55741 tcgttcgacc cgagcgtact ggcgattaaa attaacattt accgcgtggc gaaagattca
    55801 cgcatcatcg actcgatgat ccacgccgca cacaacggta agaaagtcac cgtggtggtt
    55861 gagttacagg cgcgtttcga cgaagaagcc aacattcact gggcgaagcg cctgaccgaa
    55921 gcaggcgtgc acgttatctt ctctgcgccg gggctgaaaa ttcacgccaa actgttcctg
    55981 atttcacgta aagaaaatgg tgaagtggtg cgttacgcac acatcgggac cggaaatttt
    56041 aacgaaaaaa ccgcgcgtct ttatactgac tattcgttgc tgaccgccga tgcgcgcatc
    56101 accaacgaag tacggcgggt gttcaacttt attgaaaacc cataccgtcc ggtgacattt
    56161 gattatttaa tggtgtcgcc gcaaaactcc cgccgcctgt tgtatgaaat ggtggaccgc
    56221 gaaatcgcca acgcgcagca agggctgccc agcggtatca ccctgaagct aaataacctt
    56281 gtcgataaag gcctggttga tcgtctgtat gcggcctcca gctccggcgt accggttaat
    56341 ctgctggttc gcggcatgtg ttcgctgatc cccaatctgg aaggcattag cgacaacatt
    56401 cgtgccatca gtattgttga ccgttatctt gaacatgacc gggtttatat ttttgaaaat
    56461 ggcggcgata aaaaggtcta cctttcttcc gccgactgga tgacgcgcaa tattgattat
    56521 cgtattgaag tggcgacacc gctgctcgat ccgcgcctga agcagcgggt gctggacatc
    56581 atcgacatat tattcagcga tacagtcaaa gcacgttata tcgataaaga actcagtaat
    56641 cgctacgttc cccgcggcaa tcgccgcaaa gtacgggcgc agttggcgat ttacgactac
    56701 atcaaatcac tcgaacaacc tgaataaccc tatgccaata cacgataaat cccctcgtcc
    56761 gcaggagttt gctgcggtcg atcttggttc aaacagtttt cacatggtca tagcccgtgt
    56821 ggtagatggt gccatgcaga ttattggccg cctgaaacag cgggtgcatc tggcggacgg
    56881 cctggggcca gataatatgt tgagtgaaga agcaatgacg cgcggtttaa actgtctgtc
    56941 gctgtttgcc gaacggctac aagggttttc tcctgccagc gtctgtatag ttggcaccca
    57001 tacactgcgt caggcgctga acgccactga ctttctgaaa cgcgcggaaa aggtcattcc
    57061 ctacccgatt gaaattattt ccggtaatga agaagcccgt ctgattttta tgggcgtgga
    57121 acatacccaa ccggagaaag gtcgcaaact ggttattgat attggcggcg gatctacgga
    57181 actggtgatt ggtgaaaatt tcgaacctat tctcgttgaa agccgccgga tgggttgtgt
    57241 cagctttgcc cagctttatt tccctggcgg ggtcatcaat aaagagaatt tccagcgcgc
    57301 tcgtatggcg gcagcacaaa aactggaaac gttaacctgg caattccgta ttcagggctg
    57361 gaacgtggca atgggcgctt ccggtaccat aaaagcagcc catgaagtgt taatggaaat
    57421 gggcgagaaa gacgggataa ttaccccgga acgtctggaa aaactggtaa aagaagtttt
    57481 acgtcaccgt aatttcgcat cgctgagttt accgggtctt tccgaagagc ggaaaacagt
    57541 cttcgttcct ggactggcga ttttatgcgg tgtgtttgat gctttagcca tccgtgaact
    57601 gcgcctttct gacggggcgt tacgcgaagg cgtactgtat gaaatggaag gacgtttccg
    57661 tcatcaggat gtgcgtagtc gcaccgccag cagcctcgcc aaccagtatc acatcgacag
    57721 cgaacaggcc cgacgggtgc tggataccac tatgcaaatg tacgaacagt ggcgggaaca
    57781 gcaaccgaag ctggcgcatc cgcaactgga ggcgctactg cgatgggccg ccatgctgca
    57841 tgaggtcggg ttgaatatca accacagcgg tttgcatcgc cactcagctt atattctgca
    57901 aaacagcgac ttgccgggtt ttaatcagga acaacagcta atgatggcga cactggtgcg
    57961 ctatcaccgt aaagcgatta agctcgacga tctgccgcgc tttaccttgt ttaagaagaa
    58021 acagttcctg ccactgattc agctattgcg ccttggcgta ttactcaata atcaacgtca
    58081 ggcaaccact acaccgccaa cattgacgct gattaccgat gacagtcact ggacactgcg
    58141 ttttccgcat gactggttta gtcagaatgc gctggtactg cttgatctgg aaaaggagca
    58201 agaatactgg gaaggcgtgg ctggctggcg gttgaaaatt gaagaagaaa gtacaccaga
    58261 aatcgccgct taatgctttg cgggccgacg agaaatgtcg gcccgcatta ttcaggcact
    58321 ttcgcgaatg ggttcgattt cattcagcgt atcaattaac ggttgcggct taccaataag
    58381 ataaccctgc atataatcga tccccaaaga gaacaccgcc tcgcggatct cttcgttttc
    58441 aacgtactct gccactaccc gcattttctt cattcgcgcc aggtggcaaa tcgacgccac
    58501 tatctgataa tccagactat ttgacacaat attgcggata aaactgccgt caattttaag
    58561 caaatcggca ttcacatttt taagccgcgc atagctggca tagccggtgc cgaaatcatc
    58621 aatcgcaatc tggcagccta attcctgaag atgctgcaag gtgatttgcg cctgcttaac
    58681 atttgtcaga gcattacttt cggtgacttc aaaaataagt tgccacgctt caatttgata
    58741 tttagccagc agctgactga cttcaacggg aaaacgagcc tgacataccg aggttggcga
    58801 cagattaatc gcaaaacggt gagcgggcat cttcgctctg ttttcagcca taaattgcag
    58861 cgtatgctca atgacccaca tgtcgatact cgacgataaa ccaaattcgt gcgcgaccgg
    58921 caagaagctg tcggggctga tcagttcatc attctcacct ttcatgcgca gaagaatttc
    58981 atggtaaaca tcaccacgca taccggtaat cggctgggcc atcaggaaaa aatggttgtg
    59041 ttccagcgcc tgctgtagcc gattcatcat cgcgacttta tctttcaatt cgcgttgcaa
    59101 atacattgcc ccgcgacgct gcatattttc cggggcgttg gtcacgatgg aaagctcggc
    59161 gaccgtattt agctctccca gcagcaggta gatatgattc actggcgagc gcacatagca
    59221 gtaactgacg ccaatctgcg gttgcatcgg cattccatcc caaaagaaac gaaattgctt
    59281 gagatggcta tccagtgcgg taatgcgctc ctggtgcgat tctgtattca gtcgcagcgc
    59341 gagatcgtta cccgaaagct gataaacatc ttcacccggt tccagcaagg gtgacagcca
    59401 gtgagaaagt ttttgcttgt attgaatccg tagcatgatg ccatagttct taaccagcat
    59461 ttccatgcca gggatgcgta aataacaaag cgcagaccag ggggcatcac gcaacgcgcg
    59521 attcagggcg cgaacatttg gcagatgaac caccgggtcc acatacgcaa gccgctgaat
    59581 gcgtctgact accgctctct gacgggttgc cagtacagcc atataattga caataaaaga
    59641 gaataccaga taactggagg aggttatggt cagctgcgtg gtatagccag gataaatggg
    59701 aatgtaattt tgatagctgt ggatgctgat catcaacacg accgcccaga gcagcgaaat
    59761 cagcttataa ccatagcgca tcgctcccca catcatcagg ggcagcaata atgacaaggt
    59821 atagttggtg ctaaaaattg tgcttttttc atttaacggc atgcataaca gcagcagtaa
    59881 agcacctaat gccagtagcc agagtgcgaa ctcttttttg gtgactttga catcaacctg
    59941 ctgttttaat tgcgaataat aactacgtaa ataaaacgga tttcgcacta cacgaatgat
    60001 gaagtagcac agcgggacac caatcagatt gcccaccagt aaggcctgat aattgattaa
    60061 ggtcccgagg ttaaaaggca tgacgccgac cagattttct ctgctcgcca gtaatcctac
    60121 aaacgcagca aactggaaaa gtatcagaaa cagcgttgca ggaaacacaa tctgccagaa
    60181 tatacgctgg gaaattaaac gggtatcacc atgtgaaacg ttgttacgcc ggggagtaaa
    60241 gaccctgtaa ccgccccaac agagaatgat aatgataata aaattagccg ttaatgagag
    60301 cgtttcgtaa aaacccagct ctgcatattt gcggacaaaa atccctaagg cgatccctgg
    60361 caatgccgcc cagctgaaaa acatcatcat gctgatcatc agagccagag gcagataaaa
    60421 gagaaaaacc tcaccggaag aaatatgcgc gaaagtatta atgtgggcga aaatgggcaa
    60481 gattaaagaa ggcaggaaca gcggaagccc ccaccattta tcacgtattt ttatataagt
    60541 tgcattcagt ttcatagatg ctcagcagaa tcccccacat cctgaaggag gtgtattcag
    60601 acaggcatcc cacctgactt cgaatgatga ttattcatca ctatagagag cattgattct
    60661 aagtgtcata tgaaagttcc aattgatata tatcaaacaa aataaccctg attaatgaat
    60721 tattacgttt atcatgttaa ttcatcatta ttacatcatc attgtaaata attaaattaa
    60781 cttccataac attaaaatat gtatccactg acgctttttt acataacgaa gaattgacca
    60841 ttttgtcctg ttgtgcctta atgtaagtac cgtccacagc gtgggacata cttcaaggaa
    60901 ccttttgtga gtcaggcaac cagtatgcga aaacgacacc gatttaacag tcgcatgacc
    60961 cgtatcgtac tgctcatcag ctttatcttc ttctttggcc gttttatcta ctcgtccgtc
    61021 ggtgcatggc agcaccatca gagcaaaaaa gaagctcagc aatccacact ctccgtcgaa
    61081 tcaccggtac aacgttagcg gttaccttct ccactttcac aggacataac ggcacctcgc
    61141 tgtcggatgc ttttgctctt tgggattatc aaagcggcag atattctttc atcttaa
//
LOCUS       DADXDL010000016        59537 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.016, whole genome shotgun sequence.
ACCESSION   DADXDL010000016 DADXDL010000000
VERSION     DADXDL010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 59537)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59537)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59537
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.016"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            50..2593
                     /gene="nirB"
                     /locus_tag="IRB70_001290"
     CDS             50..2593
                     /gene="nirB"
                     /locus_tag="IRB70_001290"
                     /EC_number="1.7.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-nitrite reductase large subunit"
                     /protein_id="HBC0631231.1"
                     /translation="MSKVRLAIIGNGMVGHRFIEDLLDKSDAANFDITVFCEEPRIAY
                     DRVHLSSYFSHHTAEELSLVREGFYEKHGIKVLVGERAITINRQEKVIHSSAGRTVFY
                     DKLIMATGSYPWIPPIKGSDTQDCFVYRTIEDLNAIESCARRSKRGAVVGGGLLGLEA
                     AGALKNLGIETHVIEFAPMLMAEQLDQMGGEQLRRKIESMGVRVHTSKNTLEIVQEGV
                     EARKTMRFADGSELEVDFIVFSTGIRPRDKLATQCGLDVAPRGGIVINDSCQTSDPDI
                     YAIGECASWNNRVFGLVAPGYKMAQVAVDHILGSENAFEGADLSAKLKLLGVDVGGIG
                     DAHGRTPGARSYVYLDESKEIYKRLIVSEDNKTLLGAVLVGDTSDYGNLLQLVLNAIE
                     LPENPDSLILPAHSGSGKPSIGVDKLPDSAQICSCFDVTKGDLIAAINKGCHTVAALK
                     AETKAGTGCGGCIPLVTQVLNAELAKQGIEVNNNLCEHFAYSRQELFHLIRVEGIKTF
                     EELLAKHGKGYGCEVCKPTVGSLLASCWNEYILKPEHTPLQDSNDNFLANIQKDGTYS
                     VIPRSPGGEITPEGLMAVGRIAREFNLYTKITGSQRLAMFGAQKDDLPEIWRQLIEAG
                     FETGHAYAKALRMAKTCVGSTWCRYGVGDSVGLGVELENRYKGIRTPHKMKFGVSGCT
                     RECSEAQGKDVGIIATEKGWNLYVCGNGGMKPRHADLLAADIDRETLIKYLDRFMMFY
                     IRTADKLTRTAPWLENLEGGIDYLKAVIIDDKLGLNAHLEEEMARLREAVVCEWTETV
                     NTPSAQTRFKHFINSDKRDPNVQMVPEREQHRPATPYERIPVTLVEDNA"
     gene            2590..2916
                     /gene="nirD"
                     /locus_tag="IRB70_001291"
     CDS             2590..2916
                     /gene="nirD"
                     /locus_tag="IRB70_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite reductase small subunit NirD"
                     /protein_id="HBC0631232.1"
                     /translation="MSQWKDICKIDDILPETGVCALLGDEQVAIFRPYHSGQVFAISN
                     IDPFFESSVLSRGLIAEHQGELWVASPLKKQRFRLSDGLCMEDEQFSVKHYDARVKDG
                     VVQLRG"
     gene            3041..3847
                     /gene="nirC"
                     /locus_tag="IRB70_001292"
     CDS             3041..3847
                     /gene="nirC"
                     /locus_tag="IRB70_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrite transporter NirC"
                     /protein_id="HBC0631233.1"
                     /translation="MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIIL
                     IFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELFTGHTMFLTFGVKAGTISHGQMW
                     AILPQTWLGNLVGSVFVAMLYSWGGGSLLPVDTSIVHSVALAKTTAPAMVLFFKGALC
                     NWLVCLAIWMALRTEGAAKFIAIWWCLLAFIASGYEHSIANMTLFALSWFGNHSEAYT
                     LAGIGHNLLWVTLGNTLSGAVFMGLGYWYATPKANRPVADKFNQTETAAG"
     gene            3866..5239
                     /gene="cobA"
                     /locus_tag="IRB70_001293"
     CDS             3866..5239
                     /gene="cobA"
                     /locus_tag="IRB70_001293"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBC0631234.1"
                     /translation="MDHLPIFCQLRDRDCLIVGGGDVAERKARLLLDAGARLTVNALA
                     FIPQFTAWADAGMLTLVEGPFDESLLDTCWLAIAATDDDALNQRVSEAAEARRIFCNV
                     VDAPKAASFIMPSIIDRSPLMVAVSSGGTSPVLARLLREKLESLLPLHLGQVAKYAGQ
                     LRGRVKQQFATMGERRRFWEKLFVNDRLAQSLANNDQKAITETTEQLINEPLDHRGEV
                     VLVGAGPGDAGLLTLKGLQQIQQADVVVYDRLVSDDIMNLVRRDADRVFVGKRAGYHC
                     VPQEEINQILLREAQKGKRVVRLKGGDPFIFGRGGEELETLCNAGIPFSVVPGITAAS
                     GCSAYSGIPLTHRDYAQSVRLITGHLKTGGKLDWENLAAEKQTLVFYMGLNQAATIQQ
                     KLIEHGMPGEMPVAIVENGTAVTQRVIDGTLTQLGELAQQMNSPSLIIIGRVVGLRDK
                     LNWFSNH"
     gene            5490..5657
                     /locus_tag="IRB70_001294"
     CDS             5490..5657
                     /locus_tag="IRB70_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfL family protein"
                     /protein_id="HBC0631235.1"
                     /translation="MNKFIKVALVGAVLATLTACTGHIENRDKNCSYDYLLHPAISIS
                     KIIGGCGPTAQ"
     gene            complement(5764..6849)
                     /locus_tag="IRB70_001295"
     CDS             complement(5764..6849)
                     /locus_tag="IRB70_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBC0631236.1"
                     /translation="MKTFPLQSLTIIEAQQKQFALVDSICRHFPGSEFLTCGDLGLTP
                     GLNQPRITQRVEQVLADAFHAQAAALVQGAGTGAIRAALAALLKPGQRLLVHDAPVYP
                     TTQVIIEQMGLTLITANFNDLSALKQVVDEQQPDAALVQHTRQQPQDSYVLADVLATL
                     CAAGVPVLTDDNYAVMKVASIGCECGANVSTFSCFKLFGPEGVGAVVGDADVINRIRA
                     TLYSGGSQIQGAQALEVLRGLVFAPVMHAVQAGVSERLLALLNGGAVPEVKSAVIANA
                     QSKVLIVEFHQPIAARVLEEAQKRGALPYPVGAESKYEIPPLFYRLSGTFRQANPQLE
                     HYAIRINPNRSGEETVLRILRESIADV"
     gene            complement(6861..8165)
                     /locus_tag="IRB70_001296"
     CDS             complement(6861..8165)
                     /locus_tag="IRB70_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfT family protein"
                     /protein_id="HBC0631237.1"
                     /translation="MDLYIQIIVVACLTGMTSLLAHRSAAVFHDGIRPILPQLIEGYM
                     NRREAGSIAFGLSIGFVASVGISFTLKTGLLNAWLLFLPTDILGVLAINSLMAFGLGA
                     IWGVLILTCLLPVNQLLTALPVDVLGSLGELSSPVVSAFALFPLVAIFYQFGWKQSLI
                     AAVVVLMTRVVVVHYFPHLNPESIEIFIGMVMLLGIAITHDLRHRDENDIDASGLSVF
                     EERTSRIIKNLPYIAIVGALIAAVASMKIFAGSEVSIFTLEKAYSAGVTPEQSQTLIN
                     QAALAEFMRGLGFVPLIATTALATGVYAVAGFTFVYAVGYLSPNPMVAAVLGAVVISA
                     EVLLLRSIGKWLGRYPSVRNASDNIRNAMNMLMEVALLVGSIFAAIKMAGYTGFSIAV
                     AIYFLNESLGRPVQKMAAPVVAVMITGILLNVLYWLGLFVPA"
     gene            complement(8177..8530)
                     /locus_tag="IRB70_001297"
     CDS             complement(8177..8530)
                     /locus_tag="IRB70_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2620 domain-containing protein"
                     /protein_id="HBC0631238.1"
                     /translation="MKKIGVAGLQREQIKKTIEATAPGCFEVFIHNDMEAAMKVKSGQ
                     LDYYIGACNTGAGAALSIAIAVIGYNKSCTIAKPGIKAKDEHIAKMIAEGKVAFGLSV
                     EHVEHAIPMLINHLK"
     gene            complement(8541..9419)
                     /locus_tag="IRB70_001298"
     CDS             complement(8541..9419)
                     /locus_tag="IRB70_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotriesterase-related protein"
                     /protein_id="HBC0631239.1"
                     /translation="MSFDSTGYTLAHEHLHIDLSGFKNNVDCRLDQYAFICQEMNDLM
                     ALGVRNVIEMTNRYMGRNAQFMLDVMRETGINVVACTGYYQDAFFPEHVATRSVQELA
                     QEMVDEIEQGIDGTELKAGIIAEIGSSEGKITPLEEKVFIAAALAHNQTGRPISTHTS
                     FSTMGLEQLALLQAHGVDLSRVTVGHCDLKDNLDNILKMIDLGAYVQFDTIGKNSYYP
                     DEKRIAMLHALRDRGLLNRVMLSMDITRRSHLKANGGYGYDFLLTTFIPQLRQSGFSQ
                     ADVDVMLRENPSQFFQ"
     gene            complement(9416..10642)
                     /locus_tag="IRB70_001299"
     CDS             complement(9416..10642)
                     /locus_tag="IRB70_001299"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBC0631240.1"
                     /translation="MARFVVLVIDSFGVGAMKDVTLVRPQDAGANTCGHILSQLPHLQ
                     LPTLEKLGLINALGYAPGDMQPSDSATWGVAELQHEGGDTFMGHQEILGTRPLPPLRM
                     PFRDVIDRVEQALVSAAWQVERRGEELQFLWVNQAVAIGDNLEADLGQVYNITANLSV
                     VSFDDAIKIGRIVREQVPVGRVITFGGLLTDSQRILDAAESKEGRFIGINAPRSGAYD
                     NGFQVVHMGYGVDEKVQVPQKLYEAGVPTVLVGKVADIVNNPYGVSWQNLVDSQRIMD
                     ITLDEFITHQTAFICTNIQETDLAGHAEDVARYAERLQVVDRNLALLVETMQPDDCLV
                     VMADHGNDPTIGHSHHTREVVPVLVYQQGLAATQLGVRTTLSDVGATVCEFFRAPPPQ
                     NGRSFLSSLRFAGDTL"
     gene            complement(10642..11805)
                     /locus_tag="IRB70_001300"
     CDS             complement(10642..11805)
                     /locus_tag="IRB70_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfX family PLP-dependent enzyme"
                     /protein_id="HBC0631241.1"
                     /translation="MFVEALKRQNPALISAALSLWQKGKIAPDSWVIDVDQILENGKR
                     LIETARLYGIELYLMTKQFGRNPWLAEKLLALGYSGIVAVDYKEARVMRRAGLPVAHQ
                     GHLVQIPCHQVVDAVAQGTDVITVFTLDKAREVSAAAVKAGRVQSVLLKVYSDDDFLY
                     PGQESGFVQHSLHEVVAEIKKLPGLHLAGLTHFPCLLWDEAVGKVLPTPNLHTLVQAR
                     DQLAKSGIAIEQLNAPSATSCTSLPLLAEYGVTHAEPGHALTGTIPANQQGDQPERIA
                     MLWLSEISHHFRGDSYCYGGGYYRRGHAQHALVFTPENQKITETNLKTVDDSSIDYTL
                     PLAGEFPVSSAVVLCFRTQIFVTRSDVVLLSGIHRGEPEIVGRYDSLGNSLGA"
     gene            complement(11889..12251)
                     /locus_tag="IRB70_001301"
     CDS             complement(11889..12251)
                     /locus_tag="IRB70_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417841.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBC0631242.1"
                     /translation="METRLNLLCEAGVIDKDICKGMMQVVNVLETEFHLPVRSEQGTM
                     AMTHMASALMRSRRGEEIEPLDNELLAELAQSSHWQAVVQLHQVLLKEFALEVNPCEE
                     GYLLANLYGLWMAANEEV"
     gene            complement(12268..13173)
                     /locus_tag="IRB70_001302"
     CDS             complement(12268..13173)
                     /locus_tag="IRB70_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631243.1"
                     /translation="MRRTFIKKEGVVITTLARYLLGEKCGNRLKTIDELATECRSSVG
                     LTQAALKTLESSGAIRIERRGRNGSYLVEMDNKALLTHVDINNVVCAMPLPYTRLYEG
                     LASGLKAQFDGIPFYYAHMRGADIRVECLLNGVYDMAVVSRLAAESYLTQKGLCLALE
                     LGPHTYVGEHQLICRKGESANVKRVGLDNRSADQKIMTDVFFGDSDVERVDLSYHESL
                     QRIVKGDVDAVIWNVVAENELTMLGLEATPLTDDPRFLQATEAVVLTRVDDYPMQQLL
                     RAVVDKQALLAHQQRVVSGEQEPSY"
     gene            complement(13333..14337)
                     /gene="trpS"
                     /locus_tag="IRB70_001303"
     CDS             complement(13333..14337)
                     /gene="trpS"
                     /locus_tag="IRB70_001303"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBC0631244.1"
                     /translation="MTKPIVFSGAQPSGELTIGNYMGALRQWVNMQDDYHCIYCIVDQ
                     HAITVRQDAQKLRKATLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFG
                     ELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDI
                     AQRFNALYGEIFKVPEPFIPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVK
                     KIKRAVTDSDEPPVVRYDVQNKAGVSNLLDILSAVTGQSIPELEKQFEGKMYGHLKGE
                     VADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLKAVYEAIGFVAKP
                     "
     gene            complement(14330..15088)
                     /gene="gph"
                     /locus_tag="IRB70_001304"
     CDS             complement(14330..15088)
                     /gene="gph"
                     /locus_tag="IRB70_001304"
                     /EC_number="3.1.3.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycolate phosphatase"
                     /protein_id="HBC0631245.1"
                     /translation="MNKFEDIRGVAFDLDGTLVDSAPGLATAVDMALYALELPVAGEE
                     RVITWIGNGADVLMERALTWARQERATLRKTMGKPPVDDDIPAEEQVRILRKLFDRYY
                     GEVAEEGTFLFPHVADTLGALQAKGLPLGLVTNKPTPFVAPLLEALDIAKYFSVVIGG
                     DDVQNKKPHPDPLLLVAERMGIAPQQMLFVGDSRNDIQAAKAAGCPSVGLTYGYNYGE
                     AIDLSQPDVIYQSINDLLPALGLPHSENQESKND"
     gene            complement(15081..15758)
                     /gene="rpe"
                     /locus_tag="IRB70_001305"
     CDS             complement(15081..15758)
                     /gene="rpe"
                     /locus_tag="IRB70_001305"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBC0631246.1"
                     /translation="MKQYLIAPSILSADFARLGEDTAKALAAGADVVHFDVMDNHYVP
                     NLTIGPMVLKSLRNYGITAPIDVHLMVKPVDRIVPDFAAAGASIITFHPEASEHVDRT
                     LQLIKENGCKAGLVFNPATPLSYLDYVMDKLDVILLMSVNPGFGGQSFILQTLDKLRE
                     VRRRIDESGFDIRLEVDGGVKVNNIGEIAAAGADMFVAGSAIFDQPDYKKVIDEMRSE
                     LAKVSHE"
     gene            complement(15776..16612)
                     /gene="dam"
                     /locus_tag="IRB70_001306"
     CDS             complement(15776..16612)
                     /gene="dam"
                     /locus_tag="IRB70_001306"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
                     /protein_id="HBC0631247.1"
                     /translation="MKKNRAFLKWAGGKYPLLDDIKRHLPKGECLVEPFVGAGSVFLN
                     TDFSRYILADINSDLISLYNIVKMRTDEYVQAARELFVPETNCAEVYYQFREEFNKSQ
                     DPFRRAVLFLYLNRYGYNGLCRYNLRGEFNVPFGRYKKPYFPEAELYHFAEKAQNAFF
                     YCESYADSMARADDASVVYCDPPYAPLSATANFTAYHTNSFTLEQQAHLAEIAEGLVD
                     RHIPVLISNHDTMLTREWYQRAKLHVVKVRRSISSNGGTRKKVDELLALYKPGVVSPA
                     KK"
     gene            complement(16719..18005)
                     /gene="damX"
                     /locus_tag="IRB70_001307"
     CDS             complement(16719..18005)
                     /gene="damX"
                     /locus_tag="IRB70_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein DamX"
                     /protein_id="HBC0631248.1"
                     /translation="MDEFKPEDELKPDPSDRRTGRSRQSSERSERTERGEPQINFDDI
                     ELDDTDDRRPTRAQKERNDEPEIEEEIDESEDEIVDEERVERRPRKRKKAASKPASRQ
                     YMMMGVGILVLLLLIIGIGSALKAPSTSSSDQTASGEKSIDLAGNATDQANGVQPAPG
                     TTSAENTQQDVFLPPISSTPTQGQTPAATDGQQRVEVQGDLNNALTQPQNQQQLNNVA
                     VNSTLPTEPATVAPVRNGNASRDTAKTQTAERPATTRPARQQAVIEPKKPQATVKTEP
                     KPVAQTPKRTEPAAPVASTKAPAATSTPAPKETATTAPVQTASPAQTTATPAAGGKTA
                     GNVGSLKSAPSSHYTLQLSSSSNYDNLNGWAKKENLKNYVVYETTRNGQPWYVLVSGV
                     YASKEEAKKAVSTLPADVQAKNPWAKPLRQVQADLK"
     gene            complement(18097..19185)
                     /gene="aroB"
                     /locus_tag="IRB70_001308"
     CDS             complement(18097..19185)
                     /gene="aroB"
                     /locus_tag="IRB70_001308"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBC0631249.1"
                     /translation="MERIVVTLGERSYPITIASGLFNEPASFLPLKSGEQVMLVTNET
                     LAPLYLDKVRGVLEQAGVNVDSVILPDGEQYKSLAVLDTVFTALLQKPHGRDTTLVAL
                     GGGVVGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
                     ASVVVDLDCLKTLPPRELASGLAEVIKYGIILDGAFFNWLEENLDALLRLDGPAMAYC
                     IRRCCELKAEVVAADERETGLRALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGMVMAA
                     RTSERLGQFSSAETQRIITLLTRAGLPVNGPREMSAQAYLPHMLRDKKVLAGEMRLIL
                     PLAIGKSEVRSGVSHELVLNAIADCQSA"
     gene            complement(19242..19763)
                     /gene="aroK"
                     /locus_tag="IRB70_001309"
     CDS             complement(19242..19763)
                     /gene="aroK"
                     /locus_tag="IRB70_001309"
                     /EC_number="2.7.1.71"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004709337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase AroK"
                     /protein_id="HBC0631250.1"
                     /translation="MAEKRNIFLVGPMGAGKSTIGRQLAQQLNMEFYDSDQEIEKRTG
                     ADVGWVFDLEGEEGFRDREEKVINELTEKQGIVLATGGGSVKSRETRNRLSARGVVVY
                     LETTIEKQLARTQRDKKRPLLHVETPPREVLEALANERNPLYEEIADVTIRTDDQSAK
                     VVANQIIHMLESN"
     gene            complement(20164..21402)
                     /gene="hofQ"
                     /locus_tag="IRB70_001310"
     CDS             complement(20164..21402)
                     /gene="hofQ"
                     /locus_tag="IRB70_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA uptake porin HofQ"
                     /protein_id="HBC0631251.1"
                     /translation="MKQWIAALLLMLIPGVQAAKPQKVTLMVDDVPVAQVLQALAEQE
                     KLNLVVSPDVSGTVSLHLTDVPWKQALQTVVKSAGLITRQEGNILSVHSIAWQNDNIA
                     RQEAEQARAQANLPLENRNITLQYADAGELAKAGEKLLSAKGSMTVDKRTNRLLLRDN
                     KTALSTLEQWVAQMDLPVGQVELSAHIVTINEKSLRELGVKWTLADAQQAGGVGQVTT
                     LGSDLSVATATTHVGFNIGRINGRLLDLELSALEQKQQLDIIASPRLLASHLQPASIK
                     QGSEIPYQVSSGESGATSVEFKEAVLGMEVTPTVLQKGRIRLKLHISQNVPGQVLQQA
                     DGEVLAIDKQEIETQVEVKSGETLALGGIFTRKNKSGQDSVPLLGDIPWFGQLFRHDG
                     KEDERRELVVFITPRLVSSE"
     gene            complement(21314..21718)
                     /gene="hofP"
                     /locus_tag="IRB70_001311"
     CDS             complement(21314..21718)
                     /gene="hofP"
                     /locus_tag="IRB70_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417851.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofP"
                     /protein_id="HBC0631252.1"
                     /translation="MRGKRWLLAGIALCLLTGMRDPFKPPEDLCRISELSQWRYQGIV
                     GRGERIIGVIKDGQKKWRRVQQNDVLENGWTILQLTPDVLTLGTGTNCEPPQWLWQRQ
                     GDTNEAMDSRTTVDADTRRTGGKAAKSDTDGG"
     gene            complement(21708..22148)
                     /gene="hofO"
                     /locus_tag="IRB70_001312"
     CDS             complement(21708..22148)
                     /gene="hofO"
                     /locus_tag="IRB70_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofO"
                     /protein_id="HBC0631253.1"
                     /translation="MDMLFDWWFAASPRLRQLCWAFWLMMLVTLIFLSSTHQEESDAL
                     IRLRASHHQQWAALYRLVDTTPFSEEKTLPFSPLDFQLPGAQLVSWHPSAQGGELALK
                     TLWEAVPSAFTRLAERNVSVSRFSLSVEGDDLLFTLQLETPHEG"
     gene            complement(22132..22671)
                     /locus_tag="IRB70_001313"
     CDS             complement(22132..22671)
                     /locus_tag="IRB70_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PilN domain-containing protein"
                     /protein_id="HBC0631254.1"
                     /translation="MNPPINFLPWRQQRRTAFLRFWLLMFVAPLLLAVGITLILRLTS
                     NAEARVNAVLLQAEQQLAHSLQITKPRLLEQQQLREQRLQRQRQRQFTRDWQSALEAL
                     AALLPEHAWLTTISWQQGTLEIKGLTTSITALNALETSLCQDAFFHLNQRGGTQQDAQ
                     GRWQFEYQLTRKVSDGHAL"
     gene            complement(22671..23450)
                     /gene="hofM"
                     /locus_tag="IRB70_001314"
     CDS             complement(22671..23450)
                     /gene="hofM"
                     /locus_tag="IRB70_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000874542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein HofM"
                     /protein_id="HBC0631255.1"
                     /translation="MAFKIWQIGLHLQQQEAVAVAIVRGAKECFLQRWWRLPLENDII
                     KDGRIVDAQRLANTLLPWSRELPQRHHIMLAFPASRTLQRSFPRPSMSLGEREQTAWL
                     SGTMARELDMDPDSLRFDYSEDSLSPAYNVTAAQSKELATLLTLAERLRVHVSAITPD
                     ASALQRFLPFLPSHQQCLAWRDNEQWLWATRYRWGRKLAVGMTSAKELAAALSVDPES
                     VALCGEGGFDPWEAVSVRQPPLPPPGGDFAIALGLALGKAN"
     gene            23570..26122
                     /gene="mrcA"
                     /locus_tag="IRB70_001315"
     CDS             23570..26122
                     /gene="mrcA"
                     /locus_tag="IRB70_001315"
                     /EC_number="2.4.1.129"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312265.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase/peptidoglycan
                     DD-transpeptidase MrcA"
                     /protein_id="HBC0631256.1"
                     /translation="MKFVKYFLILAVCCILLGAGSIYGLYRYIEPQLPDVATLKDVRL
                     QIPMQIYSADGELIAQYGEKRRIPVTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIF
                     RAASVALFSGHASQGASTITQQLARNFFLSPERTLMRKIKEVFLAIRIEQLLTKDEIL
                     ELYLNKIYLGYRAYGVGAAAQVYFGKTVDQLTLNEMAVIAGLPKAPSTFNPLYSMDRA
                     VARRNVVLSRMLDEGYITQQQFDQTRTEAINANYHAPEIAFSAPYLSEMVRQEMYNRY
                     GESAYEDGYRIYTTITRKVQQAAQQAVRNNVLDYDMRHGYRGPANVLWKVGESAWDNN
                     KITDTLKALPTYGPLLPAAVTSANPQEATAMLADGSTVALSMEGVRWARPYRSDTQQG
                     PTPRKVTDVLQTGQQIWVRQVGDAWWLAQVPEVNSALVSINPQNGAVMALVGGFDFNQ
                     SKFNRATQALRQVGSNIKPFLYTAAMDKGLTLASMLNDVPISRWDAGAGSDWQPKNSP
                     PQYAGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYLQRFGFPAQNIVHTESLALGSA
                     SFTPMQVARGYAVMANGGFLVDPWFISKIENDQGGVIFEAKPKVACPECDIPVIYGDT
                     QKSNVLENNDVEDVAISREQQNVSVPMPQLEQANQALVAKTGAQEYAPHVINTPLAFL
                     IKSALNTNIFGEPGWQGTGWRAGRDLQRHDIGGKTGTTNSSKDAWFSGYGPGVVTSVW
                     IGFDDHRRNLGHTTASGAIKDQISGYEGGAKSAQPAWDAYMKAVLEGVPEQPLTPPPG
                     IVTVNIDRSTGQLANGGNSREEYFIEGTQPTQQAVHEVGTTIIDNGEAQELF"
     gene            complement(26291..26851)
                     /gene="nudE"
                     /locus_tag="IRB70_001316"
     CDS             complement(26291..26851)
                     /gene="nudE"
                     /locus_tag="IRB70_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP compounds hydrolase NudE"
                     /protein_id="HBC0631257.1"
                     /translation="MSKSLQKPTILNVETVARSRLFTVESVDLEFSNGVRRVYERMRP
                     TNREAVMIVPIVDDHLILIREYAVGTESYELGFSKGLIDPGESVYEAANRELKEEVGC
                     GANDLTFLKKLSMAPSYFSSKMNIVVAQDLYPESLEGDEPEPLPQVRWPLAHMMDLLE
                     DPDFNEARNVSALFLVREWLKGQGRL"
     gene            27171..29306
                     /gene="igaA"
                     /locus_tag="IRB70_001317"
     CDS             27171..29306
                     /gene="igaA"
                     /locus_tag="IRB70_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intracellular growth attenuator protein IgaA"
                     /protein_id="HBC0631258.1"
                     /translation="MSTIVIFLAALLACSLLAGWLIKVRSRRRQLPWTNAFADAQTRK
                     LTPEERSAVENYLESLTQVLQVPGPTGASAAPISLALNAESNNVMMLTHAITRYGIST
                     DDPNKWRYYLDSVEVHLPPFWEQYINDENTVELIHTDSLPLVISLNGHTLQEYMQETR
                     GYALQPVPSTQASIRGEESEQIELLNIRKETHEEYALSRPRGLREALLIVASFLMFFF
                     CLITPDVFVPWLAGGALLLLGAGLWGLFAPPAKSSLREIHCLRGTPRRWGLFGENDQE
                     QINNISLGIIDLVYPAHWQPYIAQDLGQQTDIDIYLDRHVVRQGRYLSLHDEVKNFPL
                     QHWLRSTIIAAGSLLVLFMLLFWIPLDMPLKFTLSWMKGAQTIEATSVKQLADAGVRV
                     GDTLRISGTGMCNIRTSGTWSAKTNSPFLPFDCSQIIWNDARSLPLPESELVNKATAL
                     TEAVNRQLHPKPEDESRVSASLRSAIQKSGMVLLDDFGDIVLKTADLCSAKDDCVRLK
                     NALVNLGNSKDWDALVKRANAGKLDGVNVLLRPVSAESLDNLVATSTAPFITHETARA
                     AQSLNSPAPGGFLIVSDEGSDFVDQPWPSASLYDYPPQEQWNAFQKLAQMLMHTPFNA
                     EGIVTKIFTDANGTQHIGLHPIPDRSGLWRYLSTTLLLLTMLGSAIYNGVQAWRRYQR
                     HRTRMMKIQAYYESCLNPQLITPSESLIE"
     gene            29371..30039
                     /gene="yrfG"
                     /locus_tag="IRB70_001318"
     CDS             29371..30039
                     /gene="yrfG"
                     /locus_tag="IRB70_001318"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312268.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP/IMP nucleotidase"
                     /protein_id="HBC0631259.1"
                     /translation="MHINIAWQDVDTVLLDMDGTLLDLAFDNYFWQKLVPETWGAKNG
                     VTPQEAMEYMRQQYHDVQHTLNWYCLDYWSEQLGLDICAMTTEMGPRAVLREDTIPFL
                     EALKASGKQRILLTNAHPHNLAVKLEHTGLDAHLDLLLSTHTFGYPKEDQRLWHAVAE
                     ATGLKAERTLFIDDSEAILDAAAQFGIRYCLGVTNPDSGIAEKQYQRHPSLNDYRRLI
                     PSLM"
     gene            30050..30451
                     /gene="hslR"
                     /locus_tag="IRB70_001319"
     CDS             30050..30451
                     /gene="hslR"
                     /locus_tag="IRB70_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated heat shock protein Hsp15"
                     /protein_id="HBC0631260.1"
                     /translation="MKEKPAVEVRLDKWLWAARFYKTRALAREMIEGGKVHYNGQRSK
                     PSKIVELNATLTLRQGNDERTVIVKAITEQRRPASEAALLYEETAESVEKREKMALAR
                     KLNALTMPHPDRRPDKKERRDLLRFKHGDSE"
     gene            30476..31354
                     /gene="hslO"
                     /locus_tag="IRB70_001320"
     CDS             30476..31354
                     /gene="hslO"
                     /locus_tag="IRB70_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417860.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBC0631261.1"
                     /translation="MPQHDQLHRYLFENFAVRGELVTVSETLQQILENHDYPQPVKNV
                     LAELLVATSLLTATLKFDGDITVQLQGDGPMNLAVINGNNNQQMRGVARVQGEIPENA
                     DLKTLVGNGYVVITITPSEGERYQGVVGLEGDTLAACLEDYFMRSEQLPTRLFIRTGD
                     VDGKPAAGGMLLQVMPAQNAQQDDFDHLATLTETIKTEELLTLPANEVLWRLYHEEEV
                     TVYDPQDVEFKCTCSRERCADALKTLPDEEVDSILAEDGEIDMHCDYCGNHYLFNAMD
                     IAEIRNNASPADPQVH"
     gene            complement(31488..33212)
                     /locus_tag="IRB70_001321"
     CDS             complement(31488..33212)
                     /locus_tag="IRB70_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4153 domain-containing protein"
                     /protein_id="HBC0631262.1"
                     /translation="MDSVELSPATRWGMIATGLLQGLVCYLLIAWLAGKNLSWIVYGV
                     PATVAFSSVLLFSVISFKQKRLWGWLALVFIATLGMSGWLKWQIDGMNPWRAEKALWD
                     FGCYLLLMAMLLLPWIQQSLRIRNDSSRYRYFYQSVWHNVLILLVIFLANGLTWLVLL
                     LWSELFKLVGITFFKTLFFATDWFIYLTLGLVTALAVILARTQSRLIDSIQKLFTLIA
                     TGLLPLVSLLTLMFIITLPFTGLSAISRHISAAGLLLTLAFLQLILMAIVRDPQKASL
                     PWTGPLRCLIKTALLVAPLYVFVAAWALWLRVAQYGWTVDRLQGALAVLVLLVWSLGY
                     FVSIVWRKGQNPLDLQGKVNFAVSLLVLVMLVLLNSPVLDSMRISVNSHMARYQSGKN
                     TPDQVTIYMLEQSGRYGRAALESLKSDAGFMKDPKRARDLLMALDGEQHLQEQVSEKV
                     LADNVLIAPGSGKPDATFWSALIQDRYNVMTCIEKDACVLVEQDLNSDGQAERILFAF
                     NDDRVIVYGFDSARKEWDALDMSLLPRQITKEKLLAAAKDGKLGTRPKAWRDLTVDGE
                     TLEINLSK"
     gene            33591..35213
                     /gene="pckA"
                     /locus_tag="IRB70_001322"
     CDS             33591..35213
                     /gene="pckA"
                     /locus_tag="IRB70_001322"
                     /EC_number="4.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBC0631263.1"
                     /translation="MRVNNGLTPQELEAYGISDVHDIVYNPSYDLLYQEELDPSLTGY
                     ERGVLTNLGAVAVDTGIFTGRSPKDKYIVRDDTTRDTFWWADKGKGKNDNKPLSPETW
                     QHLKGLVTKQLSGKRLFVVDAFCGANPDTRLSVRFITEVAWQAHFVKNMFIRPSDEEL
                     AGFKPDFIVMNGAKCTNPQWKEQGLNSENFVAFNLTERMQLIGGTWYGGEMKKGMFSM
                     MNYLLPLKGIASMHCSANVGEKGDVAVFFGLSGTGKTTLSTDPKRRLIGDDEHGWDDD
                     GVFNFEGGCYAKTIKLSKEAEPEIYNAIRRDALLENVTVREDGTIDFDDGSKTENTRV
                     SYPIYHIENIVKPVSKAGHATKVIFLTADAFGVLPPVSRLTADQTQYHFLSGFTAKLA
                     GTERGITEPTPTFSACFGAAFLSLHPTQYAEVLVKRMQAAGAQAYLVNTGWNGTGKRI
                     SIKDTRAIIDAILNGSLDNAETFTLPMFNLAIPTELPGVDTKILDPRNTYASPEQWQE
                     KAETLAKLFIDNFDKYTDTPAGAALVAAGPKL"
     gene            35328..35645
                     /locus_tag="IRB70_001323"
     CDS             35328..35645
                     /locus_tag="IRB70_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBC0631264.1"
                     /translation="MFTFIELQGFSKRRQLLLPDDEFRAFQELLIQDPTAGDIIAGTG
                     SFRKIRWNRSGMGKRGGIRIIYYNVTRNGRIYLALIYPKNEQDDLTEEQRKALKLLSE
                     KLL"
     gene            35704..36000
                     /locus_tag="IRB70_001324"
     CDS             35704..36000
                     /locus_tag="IRB70_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0631265.1"
                     /translation="MKDELFADLLASAEEMVRIEKGEETPEPEHVHTFSEIDVKAIRE
                     ATGLRQQDFAVAVGVSYDLVKSWETKRRQPTGAPRKLLLLLQANPFIINQLKTI"
     gene            complement(36032..37384)
                     /gene="envZ"
                     /locus_tag="IRB70_001325"
     CDS             complement(36032..37384)
                     /gene="envZ"
                     /locus_tag="IRB70_001325"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     EnvZ"
                     /protein_id="HBC0631266.1"
                     /translation="MRRLRFSPRSSFARTLLLIVTLLFVSLVTTYLVVLNFAILPSLQ
                     QFNKVLAYEVRMLMTDKLQLEDGTQLVVPPAFRREIYRELGISLYSNEAAEEAGLRWA
                     QHYEFLSHQMAQQLGGPTEVRVEVNKSSPVVWLKTWLSPNIWVRVPLTEIHQGDFSPL
                     FRYTLAIMLLAIGGAWLFIRIQNRPLVDLEHAALQVGKGIIPPPLREYGASEVRSVTR
                     AFNHMAAGVKQLADDRTLLMAGVSHDLRTPLTRIRLATEMMSEQDGYLAESINKDIEE
                     CNAIIEQFIDYLRIGQEMPMEMADLNAVLGEVIAAESGYEREIETALYPGSIEVKMHP
                     LSIKRAVANMVVNAARYGNGWIKVSSGTEPNRAWFQVEDDGPGIAPEQRKHLFQPFVR
                     GDSARTISGTGLGLAIVQRIVDNHNGMLELGTSERGGLSIRAWLPVPVTRAQGMTKEG
                     "
     gene            complement(37381..38100)
                     /gene="ompR"
                     /locus_tag="IRB70_001326"
     CDS             complement(37381..38100)
                     /gene="ompR"
                     /locus_tag="IRB70_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014646135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator OmpR"
                     /protein_id="HBC0631267.1"
                     /translation="MQENYKILVVDDDMRLRALLERYLTEQGFQVRSVANAEQMDRLL
                     TRESFHLMVLDLMLPGEDGLSICRRLRSQSNPMPIIMVTAKGEEVDRIVGLEIGADDY
                     IPKPFNPRELLARIRAVLRRQANELPGAPSQEEAVIAFGKFKLNLGTREMFREDEPMP
                     LTSGEFAVLKALVSHPREPLSRDKLMNLARGREYSAMERSIDVQISRLRRMVEEDPAH
                     PRYIQTVWGLGYVFVPDGSKA"
     gene            38328..38804
                     /gene="greB"
                     /locus_tag="IRB70_001327"
     CDS             38328..38804
                     /gene="greB"
                     /locus_tag="IRB70_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312275.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreB"
                     /protein_id="HBC0631268.1"
                     /translation="MKTPLVTREGYEKLKQELNYLWREERPEVTKKVTWAASLGDRSE
                     NADYQYNKKRLREIDRRVRYLTKCMENLKIVDYSPQQEGKVFFGAWVEIENDDGVTHR
                     FRIVGYDEIFGRKDYISIDSPMARALLKKEVGDLAVVNTPAGEASWYVNAIEYVKP"
     gene            38901..41222
                     /locus_tag="IRB70_001328"
     CDS             38901..41222
                     /locus_tag="IRB70_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417866.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBC0631269.1"
                     /translation="MMNDSFCRIIAGEIQARPEQVDAAVRLLDEGNTVPFIARYRKEI
                     TGGLDDTQLRNLETRLSYLRELEERRQAILKSISEQGKLTDDLANAINATLSKTELED
                     LYLPYKPKRRTRGQIAIEAGLEPLADLLWSDPSHTPEVAAAQYIDADKGVADTKAALD
                     GARYILMERFAEDAALLAKVRDYLWKNAHLVSTVVNGKEEEGAKFRDYFNHHEPLSTV
                     PSHRALAMFRGRNEGILQLSLNADPQFEEPPKESYCEQIIMDHLGLRLNNAPADSWRK
                     GVVSWTWRIKVLMHLETELMGTVRERAEDEAINVFARNLHDLLMAAPAGLRATMGLDP
                     GLRTGVKVAVVDATGKLVATDTIYPHTGQAAKAAMTVAALCEKHNVELVAIGNGTASR
                     ETERFYLDVQKQFPKVTAQKVIVSEAGASVYSASELAAQEFPDLDVSLRGAVSIARRL
                     QDPLAELVKIDPKSIGVGQYQHDVSQTQLARKLDAVVEDCVNAVGVDLNTASVPLLTR
                     VAGLTRMMAQNIVAWRDENGQFQNRQQLLKVSRLGPKAFEQCAGFLRINHGDNPLDAS
                     TVHPEAYPVVERILAATQQALKDLMGNSSELRNLKASDFTDEKFGVPTVTDIIKELEK
                     PGRDPRPEFKTAQFADGVETMNDLQPGMILEGAVTNVTNFGAFVDIGVHQDGLVHISS
                     LSNKFVEDPHTVVKAGDIVKVKVLEVDLQRKRISLTMRLDEQPGETNARRGGGNERPQ
                     NNRPAAKPRGREAQPAGNSAMMDALAAAMGKKR"
     gene            41660..41887
                     /gene="feoA"
                     /locus_tag="IRB70_001329"
     CDS             41660..41887
                     /gene="feoA"
                     /locus_tag="IRB70_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transporter A"
                     /protein_id="HBC0631270.1"
                     /translation="MQYTPDTAWKITGFSREISPAYRQKLLSLGMLPGSSFNVVRVAP
                     LGDPIHIETRRVSLVLRKKDLALLEVEAVSC"
     gene            41904..44225
                     /gene="feoB"
                     /locus_tag="IRB70_001330"
     CDS             41904..44225
                     /gene="feoB"
                     /locus_tag="IRB70_001330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312278.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(2+) transporter permease subunit FeoB"
                     /protein_id="HBC0631271.1"
                     /translation="MKKLTIGLIGNPNSGKTTLFNQLTGARQRVGNWAGVTVERKEGQ
                     FSTTDHQVTLVDLPGTYSLTTISSQTSLDEQIACHYILSGDADLLINVVDASNLERNL
                     YLTLQLLELGIPCIVALNMLDIAEKQNIRIEIDALSARLGCPVIPLVSTRGRGIEALK
                     LAIDRYKANENVELVHYAQPLLNEADSLAKVMPSDIPLKQRRWLGLQMLEGDIYSRAY
                     AGEASQHLDAALARLCNEMDDPALHIADARYQCIAAICDVVSNTLTAEPSRFTTAVDK
                     IVLNRFLGLPIFLFVMYLMFLLAINIGGALQPLFDVGSVALFVHGIQWIGYTLHFPDW
                     LTIFLAQGLGGGINTVLPLVPQIGMMYLFLSFLEDSGYMARAAFVMDRLMQALGLPGK
                     SFVPLIVGFGCNVPSVMGARTLDAPRERLMTIMMAPFMSCGARLAIFAVFAAAFFGQN
                     GALAVFSLYMLGIVMAVLTGLMLKYTIMRGEATPFVMELPVYHVPHVKSLIIQTWQRL
                     KGFVLRAGKVIIIVSIFLSAFNSFSLSGKIVDNINDSALASVSRVITPVFKPIGVHED
                     NWQATVGLFTGAMAKEVVVGTLNTLYTAENIQDEEFNPAEFNLGEELFSAVDETWQSL
                     KDTFSLSVLMNPIEASKGDGEMGTGAMGVMDQKFGSAAAAYSYLIFVLLYVPCISVMG
                     AIARESSRGWMGFSILWGLNIAYSLATLFYQVASYSQHPTYSLVCILAVILFNIVVIG
                     LLRRARSRVDIELLATRKSVSSCCAASTTGDCH"
     gene            44225..44461
                     /gene="feoC"
                     /locus_tag="IRB70_001331"
     CDS             44225..44461
                     /gene="feoC"
                     /locus_tag="IRB70_001331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[Fe-S]-dependent transcriptional repressor FeoC"
                     /protein_id="HBC0631272.1"
                     /translation="MASLIQVRDLLALRGRMEAAQISQTLNTPQPMINAMLQQLESMG
                     KAVRIQEEPDGCLSGSCKSCPEGKACLREWWALR"
     gene            44664..45542
                     /gene="rpnA"
                     /locus_tag="IRB70_001332"
     CDS             44664..45542
                     /gene="rpnA"
                     /locus_tag="IRB70_001332"
                     /EC_number="3.1.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination-promoting nuclease RpnA"
                     /protein_id="HBC0631273.1"
                     /translation="MSKKQSSTPHDALFKLFLRQPETARDFLAFHLPAPIHALCDMKT
                     LKLESSSFIDDDLRESYSDVLWSVKTEQGPGYIYCLIEHQSTSNKLIAFRMMRYAIAA
                     MQNHLDAGYKTLPMVVPLLFYHGIESPYPYSLCWLDCFADPNLARQLYASAFPLIDVT
                     VMPDDEIMQHRRMALLELIQKHIRQRDLMGLVEQMACLLSSGYANDRQIKGLFNYILQ
                     TGDAVRFNDFIDGVAERSPKHKESLMTIAERLRQEGEQSKALHIAKIMLESGVPLADI
                     MRFTGVSEEELAAASQ"
     gene            complement(45571..46341)
                     /gene="bioH"
                     /locus_tag="IRB70_001333"
     CDS             complement(45571..46341)
                     /gene="bioH"
                     /locus_tag="IRB70_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pimeloyl-ACP methyl ester esterase BioH"
                     /protein_id="HBC0631274.1"
                     /translation="MNNIWWQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSHFTLHL
                     VDLPGFGRSRGFGAMSLADMAEAVLRQAPDKAIWLGWSLGGLVASQIALTHPERVQAL
                     VTVASSPCFSARDEWPGIKPDVLAGFQQQLSDDFQRTVERFLALQTMGTETARQDARA
                     LKKTVLALPMPEVDVLNGGLEILKTVDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPML
                     DKLWPHSESYIFAKAAHAPFISHPAEFCRMLVALKQRV"
     gene            46379..47062
                     /gene="gntX"
                     /locus_tag="IRB70_001334"
     CDS             46379..47062
                     /gene="gntX"
                     /locus_tag="IRB70_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417872.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA utilization protein GntX"
                     /protein_id="HBC0631275.1"
                     /translation="MLTVPGLCWLCRMPLALGHWGICSVCSRAARTDKTLCPQCGLPA
                     THAHLPCGRCLQKPPPWQRLVTVADYAPPLSPLIHQLKFSRRCEIASALSRLLLLEVL
                     HARRATGLQLPDRIISVPLWQRRHWRRGFSQSDLLCQPLSRWLHCRWDSEAVTRTRAA
                     ATQHFLSARLRKRNLKNAFRLELPVQGRHMVIVDDVVTTGSTVAEIAQLLLRNGAATV
                     QVWCLCRTL"
     gene            47121..47696
                     /gene="nfuA"
                     /locus_tag="IRB70_001335"
     CDS             47121..47696
                     /gene="nfuA"
                     /locus_tag="IRB70_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016942932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S biogenesis protein NfuA"
                     /protein_id="HBC0631276.1"
                     /translation="MIRISDAAQAHFAKLLANQEEGTQIRVFVINPGTPNAECGVSYC
                     PPDAVEATDTALKFDLLTAYVDELSAPYLEDAEIDFVTDQLGSQLTLKAPNAKMRKVA
                     DDAPLMERVEYMLQSQINPQLAGHGGRVSLMEITEDGYAILQFGGGCNGCSMVDVTLK
                     EGIEKQLLNEFPELKGVRDLTEHQRGEHSYY"
     gene            48057..49373
                     /gene="gntT"
                     /locus_tag="IRB70_001336"
     CDS             48057..49373
                     /gene="gntT"
                     /locus_tag="IRB70_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312284.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HBC0631277.1"
                     /translation="MPLVIVAIGVILLLLLMIRFKMNGFIALVLVALAVGLMQGMPLD
                     KVIGSIKAGVGGTLGSLALIMGFGAMLGKMLADCGGAQRIATTLIAKFGKKHIQWAVV
                     LTGFTVGFALFYEVGFVLMLPLVFTIAASANIPLLYVGVPMAAALSVTHGFLPPHPGP
                     TAIATIFNADMGKTLLYGTILAIPTVILAGPVYARVLKGIDKPIPEGLYSAKTFSEEE
                     MPSFGVSVWTSLVPVVLMAMRAIAEMILPKGHAFLPVAEFLGDPVMATLIAVLIAMFT
                     FGLNRGRSMDQINDTLVSSIKIIAMMLLIIGGGGAFKQVLVDSGVDKYIASMMHETNI
                     SPLLMAWSIAAVLRIALGSATVAAITAGGIAAPLIATTGVSPELMVIAVGSGSVIFSH
                     VNDPGFWLFKEYFNLTIGETIKSWSMLETIISVCGLVGCLLLNMVI"
     gene            complement(49421..51502)
                     /gene="malQ"
                     /locus_tag="IRB70_001337"
     CDS             complement(49421..51502)
                     /gene="malQ"
                     /locus_tag="IRB70_001337"
                     /EC_number="2.4.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-alpha-glucanotransferase"
                     /protein_id="HBC0631278.1"
                     /translation="MESKRLDNAALAAGISPNYINAHGKPQSISAETKRRLLDAMHQR
                     TATKVAVTPVPNVMVYTSGKKMPMAVEGSGEYSWLLTTEEGTQYKGHVTGGKAFNLPT
                     KLPEGYHTLTVTQDDQRAHCRVIVAPKRCYEPQALLNKQKLWGACVQLYTLRSEKNWG
                     IGDFGDLKAMLVDVAKRGGSFIGLNPIHALYPANPESASPYSPSSRRWLNVIYIDVNA
                     VEDFHLSEEAQAWWKLPTMQQTLQQARDADWVDYSTVTALKMTALRMAWKGFAQRDDE
                     QMAAFRQFVAEQGDSLFWQAAFDALHAQQVKEDEMRWGWPAWPEMYQNVDSPEVRQFC
                     EEHRDDVDFYLWLQWLAYSQFAACWEISQDYEMPIGLYRDLAVGVAEGGAETWCDREL
                     YCLKASVGAPPDILGPLGQNWGLPPMDPHIITARAYEPFIELLRANMQNCGALRIDHV
                     MSMLRLWWIPYGETADQGAYVHYPVDDLLSILALESKRHRCMVIGEDLGTVPVEIVGK
                     LRSSGVYSYKVLYFENDHEKTFRAPKAYPEQSMAVAATHDLPTLRGYWESGDLTLGKT
                     LGLYPDEVVLRGLYQDRELAKQGLLDALHKYGCLPKRAGHKASLMSMTPTLNRGLQRY
                     IADSNSALLGLQPEDWLDMADPVNIPGTSYQYKNWRRKLSATLEAMFADDGVNKLLKD
                     LDRRRRAAAKK"
     gene            complement(51512..53905)
                     /gene="malP"
                     /locus_tag="IRB70_001338"
     CDS             complement(51512..53905)
                     /gene="malP"
                     /locus_tag="IRB70_001338"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrin phosphorylase"
                     /protein_id="HBC0631279.1"
                     /translation="MSQPIFNDKQFQEALSRQWQRYGLNSAAEMTPRQWWLAVSEALA
                     EMLRAQQFAKPVANQRHVNYISMEFLIGRLTGNNLLNLGWYQDVQDSLKAYDINLTDL
                     LEEEIDPALGNGGLGRLAACFLDSMATVGQSATGYGLNYQYGLFRQSFVDGKQVEAPD
                     DWHRGNYPWFRHNEALDVQVGIGGKVTKDGRWEPEFTITGQAWDLPVVGYRNGVAQPL
                     RLWQATHAHPFDLTKFNDGDFLRAEQQGINAEKLTKVLYPNDNHTAGKKLRLMQQYFQ
                     CACSVADILRRHHLAGRKLHELADYEVIQLNDTHPTIAIPELLRVLIDEHQMSWDDAW
                     AITSKTFAYTNHTLMPEALERWDVKLVKGLLPRHMQIINEINTRFKTLVEKTWPGDEK
                     VWAKLAVVHDKQVHMANLCVVGGFAVNGVAALHSDLVVKDLFPEYHQLWPNKFHNVTN
                     GITPRRWIKQCNPALAALLDKSLKKEWANDLDQLINLEKFADDAKFRQQYREIKQANK
                     VRLAEFVKVRTGIEINPQAIFDIQIKRLHEYKRQHLNLLHILALYKEIRENPQADRVP
                     RVFLFGAKAAPGYYLAKNIIFAINKVADVINNDPQVGDKLKVVFLPDYCVSAAEKLIP
                     AADISEQISTAGKEASGTGNMKLALNGALTVGTLDGANVEIAEKVGEENIFIFGHTVE
                     QVKAILAKGYDPVKWRKKDKVLDAVLKELESGKYSDGDKHAFDQMLHSIGKQGGDPYL
                     VMADFAAYVEAQKQVDVLYRDQEAWTRAAILNTARCGMFSSDRSIRDYQARIWQAKR"
     gene            54528..57233
                     /gene="malT"
                     /locus_tag="IRB70_001339"
     CDS             54528..57233
                     /gene="malT"
                     /locus_tag="IRB70_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MalT"
                     /protein_id="HBC0631280.1"
                     /translation="MLIPSKLSRPVRLDHTVVRERLLAKLSGANNFRLALITSPAGYG
                     KTTLISQWAAGKNDIGWYSLDEGDNQQERFASYLIAAVQQATNGHCAICETMAQKRQY
                     ASLTSLFAQLFIELAEWHSPLYLVIDDYHLITNPVIHESMRFFIRHQPENLTLVVLSR
                     NLPQLGIANLRVRDQLLEIGSQQLAFTHQEAKQFFDCRLSSPIEAAESSRICDDVSGW
                     ATALQLIALSARQNTHSAHKSARRLAGINASHLSDYLVDEVLDNVDLATRHFLLKSAI
                     LRSMNDALINRVTGEENGQMRLEEIERQGLFLQRMDDTGEWFCYHPLFGNFLRQRCQW
                     ELAAELPEIHRAAAESWMAQGFPSEAIHHALAAGDALMLRDILLNHAWSLFNHSELSL
                     LEESLKALPWDSLLENPQLVLLQAWLMQSQHRYGEVNTLLARAEHEIKDIREGTMHAE
                     FNALRAQVAINDGNPDEAERLAKLALEELPPGWFYSRIVATSVLGEVLHCKGELTRSL
                     ALMQQTEQMARQHDVWHYALWSLIQQSEILFAQGFLQTAWETQEKAFQLINEQHLEQL
                     PMHEFLVRIRAQLLWAWARLDEAEASARSGIEVLSSYQPQQQLQCLAMLIQCSLARGD
                     LDNARSQLNRLENLLGNGKYHSDWISNANKVRVIYWQMTGDKAAAANWLRHTAKPEFA
                     NNHFLQGQWRNIARAQILLGEFEPAEIVLEELNENARSLRLMSDLNRNLLLLNQLYWQ
                     AGRKSDAQRVLLDALKLANRTGFISHFVIEGEAMAQQLRQLIQLNTLPELEQHRAQRI
                     LREINQHHRHKFAHFDENFVERLLNHPEVPELIRTSPLTQREWQVLGLIYSGYSNEQI
                     AGELEVAATTIKTHIRNLYQKLGVAHRQAAVQHAQKLLKMMGYGV"
     gene            complement(57276..58292)
                     /gene="rtcA"
                     /locus_tag="IRB70_001340"
     CDS             complement(57276..58292)
                     /gene="rtcA"
                     /locus_tag="IRB70_001340"
                     /EC_number="6.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 3'-terminal phosphate cyclase"
                     /protein_id="HBC0631281.1"
                     /translation="MKRMIALDGAQGEGGGQILRSALSLSMITGQPFTITGIRAGRAK
                     PGLLRQHLTAVKAATEICRATVEGAELGSQRLVFRPGTVRGGDYRFAIGSAGSSTLVL
                     QTVLPALWFADGPSRVEVSGGTDNPSAPPADFIRRVLEPLLAKMGIHQQTTLLRHGFY
                     PAGGGVVATEVSPVASFNTLQLGERGNIVQMRGEVLLAGVPRHVAEREIATLVGSFSL
                     HEKNIHNLPRDQGPGNTVSLEVESENITERFFIVGEKRVSAEVVAAQLVKEVKRYLAS
                     PAAVGEYLADQLVLPMALAGAGEFTVAHPSCHLLTNIAVVERFLPVRFGLVEADGVTR
                     VSIE"
     gene            complement(58296..59522)
                     /gene="rtcB"
                     /locus_tag="IRB70_001341"
                     /pseudo
     CDS             complement(58296..59522)
                     /gene="rtcB"
                     /locus_tag="IRB70_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417879.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-splicing ligase RtcB"
BASE COUNT        14228 a        16243 c        15044 g        14022 t
ORIGIN      
        1 ttgctgaatc gttaaggtag gcggtaatag aaaagaaatc gaggcaaaaa tgagcaaagt
       61 cagactcgca attatcggta acggtatggt cggccatcgc tttatcgaag atcttcttga
      121 taaatctgat gcggccaact ttgatattac cgttttctgt gaagaaccgc gcatcgctta
      181 tgaccgcgta cacctctcgt cttacttctc tcaccacacc gccgaagagc tgtcgctggt
      241 gcgcgaaggc ttctacgaga aacacggcat caaagttctg gtcggcgaac gcgctatcac
      301 catcaaccgt caggagaagg tgattcactc cagcgccggg cgcaccgttt tttatgacaa
      361 gctgatcatg gcgaccggtt cctacccgtg gatcccgcca atcaaaggtt ctgatactca
      421 ggactgcttt gtctatcgca ctattgaaga cctcaacgcc attgaatcct gcgcccgtcg
      481 cagcaaacgc ggtgccgttg ttggtggcgg cctgttaggt ctggaagccg ctggcgcgct
      541 gaaaaactta ggtattgaaa cccacgttat cgaatttgcc cctatgctga tggcggaaca
      601 gcttgatcag atgggtggcg agcagctgcg tcgcaaaatc gaaagtatgg gcgtgcgcgt
      661 tcacaccagc aaaaacaccc ttgagattgt gcaggaaggt gtcgaagcgc gtaaaaccat
      721 gcgttttgcc gacggcagcg agctggaagt cgactttatc gtcttctcaa ccggtatccg
      781 tccgcgcgat aagctggcaa cccagtgtgg tctggacgtt gctccgcgtg ggggtattgt
      841 catcaatgat tcctgccaga cttccgatcc ggatatctac gccatcggtg aatgcgcaag
      901 ctggaacaac cgtgtatttg gtctggtagc acctggctac aaaatggcgc aggtcgccgt
      961 tgaccatatt cttggtagcg aaaacgcctt tgaaggtgct gaccttagcg ccaagttgaa
     1021 actgctgggc gtagacgtag gtggtattgg tgatgcgcac ggtcgcacgc ctggcgcacg
     1081 tagctacgtt tacctcgacg aaagcaaaga gatctacaaa cgccttattg tcagcgaaga
     1141 caacaaaacc ctgctcggtg cggtactggt gggcgatacc agcgactacg gcaacctgct
     1201 gcaactggtg ctgaacgcta tcgagctgcc ggaaaacccg gattctctga ttctgccggc
     1261 gcactctggt agcggtaagc cgtctatcgg tgttgataaa ctgccggaca gcgcgcaaat
     1321 ctgctcctgc ttcgacgtca ccaaaggcga cctgattgct gctatcaaca aaggctgcca
     1381 caccgttgcg gcgctgaaag ctgaaaccaa agcgggtact ggctgcggtg gctgtatccc
     1441 gctggtcact caggtactga acgcggaact ggcgaagcag ggcatcgaag ttaacaacaa
     1501 cctgtgcgaa cactttgctt attcgcgtca ggaactgttc catttaatcc gcgttgaagg
     1561 cattaaaacc ttcgaagaac tgctggcgaa acacggcaaa ggctacggtt gtgaagtttg
     1621 taaaccgacc gtcggttcgc tgctggcctc ctgctggaac gaatacattc tgaagccgga
     1681 acatactccg ctgcaggatt caaacgacaa cttcctcgct aacatccaga aagacggcac
     1741 ctactcggtg atcccgcgtt ctccgggcgg tgaaatcacc ccggaagggc tgatggcagt
     1801 aggtcgtatc gcgcgtgaat ttaatctcta caccaaaatc accggctccc agcgcctggc
     1861 gatgtttggc gcacagaaag acgatctgcc ggagatctgg cgtcagctga ttgaagccgg
     1921 cttcgaaacc ggtcatgcct atgcgaaagc actgcgtatg gcgaaaacct gcgtgggtag
     1981 cacctggtgc cgctacggcg ttggcgatag cgtcggcctc ggcgtggaac tggaaaaccg
     2041 ctacaaaggc atccgtactc cgcacaaaat gaagtttggt gtctccggct gtacccgtga
     2101 atgttcagaa gctcagggta aggacgtggg tatcatcgcc accgaaaaag gctggaacct
     2161 ctacgtttgt ggtaacggcg gcatgaaacc gcgtcatgcg gatctgctgg cggcggatat
     2221 cgatcgcgaa acgctgatca aatatctcga ccgcttcatg atgttctaca tccgtactgc
     2281 cgacaaactg acgcgtaccg cgccgtggtt agaaaacctt gaaggcggca tcgattacct
     2341 gaaagcggtg atcattgacg acaaactggg gctgaacgca catctggaag aagagatggc
     2401 gcgcctgcgt gaagcggtag tatgtgagtg gactgagacg gtcaatacac cgtccgcgca
     2461 gactcgcttc aaacacttca tcaacagcga caagcgtgac ccgaacgtgc agatggtgcc
     2521 agagcgcgaa cagcaccgtc cggcaacgcc gtatgaacgt atcccggtaa ctctggtgga
     2581 ggacaacgca tgagccagtg gaaagacatc tgcaaaatcg atgacatcct gcctgaaacc
     2641 ggcgtctgcg cgctgttagg tgacgagcag gtagcaattt tccgcccgta tcacagcggc
     2701 caggtgtttg cgatcagcaa catcgacccg ttcttcgagt ccagcgtgct gtcacgcggg
     2761 ctgattgcgg aacaccaggg cgagctgtgg gtcgccagcc cgctgaaaaa acagcgtttt
     2821 cgcttaagcg acggcttgtg catggaagac gaacagtttt ccgtcaagca ttacgacgcg
     2881 cgagtgaaag acggcgtggt gcagctacgc ggttaatgtt ttaacgggag gcacaatgcc
     2941 tccccttttt gcatggtcct gtaataacct tggtatattg caggacattt tttaaacttt
     3001 ttgttttatt ttttgttttt attttttaaa ggataatcaa atgtttacag acactattaa
     3061 taagtgtgcg gctaacgctg cgcgcattgc acgcctgtcg gcaaataacc cgctcggctt
     3121 ctgggtcagc tccgcaatgg cgggggcgta tgtgggtctt gggatcatcc tgattttcac
     3181 gctcggtaat ttgctcgacc cgtccgtacg tcctctggtg atgggcgcga cctttggtat
     3241 cgccttaacg ctggtcatta ttgctggttc tgaactgttc accggacaca ccatgttcct
     3301 cacctttgga gtgaaagcgg gcactatcag ccacgggcaa atgtgggcaa tcctgccgca
     3361 aacctggctg ggtaacctgg ttggttccgt ctttgttgcc atgctctata gctggggcgg
     3421 cggtagcctg ctgccggtag ataccagcat cgttcactcc gtcgcgctgg ctaaaaccac
     3481 tgcaccggca atggtactgt tcttcaaagg tgcattgtgt aactggctgg tttgcctggc
     3541 tatctggatg gcgctgcgca ctgaaggggc ggcgaaattt atcgctatct ggtggtgtct
     3601 gctggcattt atcgcgtccg gctacgagca ctccatcgcg aacatgacgc tgttcgccct
     3661 ctcctggttt ggcaaccaca gcgaagccta cacgctggcg ggtattggtc ataacctgct
     3721 gtgggtgacg ctgggtaata ctttatcagg tgccgtattc atgggattgg gttattggta
     3781 tgctacgccg aaagcgaatc gtccggttgc ggacaaattt aatcaaactg aaacagctgc
     3841 cggttaatta ctaaggggtt tttacgtgga tcatttgcct atattttgcc aattacgcga
     3901 tcgcgactgt ctgattgtcg gcggtggtga tgtcgcggaa cgcaaagcaa ggttgctgtt
     3961 agacgcaggc gctcgcttaa cggtgaatgc attagcgttt attccacagt tcaccgcatg
     4021 ggcagatgca ggcatgttaa ccctcgtcga agggccattt gatgaaagcc ttctcgacac
     4081 ctgctggctg gcgattgcag cgacagatga tgacgcgctt aaccagcgcg tcagtgaagc
     4141 cgctgaagct cgtcgcatct tctgtaacgt ggtcgatgcg ccgaaagccg ccagctttat
     4201 tatgccgtca attattgacc gctcaccgct catggtcgcg gtctcctctg gcggcacctc
     4261 tccggttctg gcacgcctgt tgcgtgaaaa acttgaatca ctgctgccgt tgcatctggg
     4321 ccaggtagcg aaatacgccg ggcaattacg cggtcgagtg aaacaacagt tcgccacaat
     4381 gggtgaacgt cgccgtttct gggaaaaact gttcgttaat gaccgtctgg cgcagtcgct
     4441 ggcaaacaac gatcagaaag ccattactga aacgaccgaa caattaatca acgaaccgct
     4501 cgaccatcgc ggtgaagtgg tgctggttgg cgcaggtccg ggcgatgccg ggctgctgac
     4561 actgaaagga ctgcaacaaa ttcagcaggc agatgtggtg gtctacgacc gtctggtttc
     4621 tgacgatatt atgaatctgg tacgccgcga tgctgatcgc gttttcgtcg gcaaacgcgc
     4681 gggataccac tgcgtaccgc aggaagagat taaccagatc ctgctgcggg aagcgcaaaa
     4741 aggcaaacgc gtggtgcgac tgaaaggcgg cgatccgttt atttttggcc gtggtggcga
     4801 agagctggaa acactgtgca atgcaggcat tccgttctcg gtggttccgg gtattaccgc
     4861 agcttctggt tgctctgcct attcgggtat tccgctcacg catcgcgatt atgcccagag
     4921 cgtacgctta attaccggac acttaaaaac cggtggcaaa ctggactggg aaaacctggc
     4981 ggcagaaaaa cagacgctgg tgttctatat ggggttgaat caggccgcga ctattcagca
     5041 aaagctgatt gaacacggta tgcctggcga aatgccggtg gcaattgtcg aaaacggaac
     5101 ggcagtcacg cagcgcgtga ttgacggtac gctcacgcag ctgggcgaac tggcgcagca
     5161 aatgaacagt ccatcgctaa ttattattgg tcgggttgtt ggcctgcgcg ataaattgaa
     5221 ctggttctct aaccattaat ttaaccaggg ccagagaatt ctggcctttt tcgtttacaa
     5281 ctctctttat atattcagca gataaaaata ccccccttaa taaatattat ctgctaatgg
     5341 gttatattca ccgttacagc gacttacaaa attaagtcat tcgttcactg acgccaatta
     5401 aatattcctg tatcattctt aatgagcagt ctgcttatat tcatataatc aatgaatatt
     5461 aatcaatata taatacatag ggaatgtaaa tgaacaaatt tattaaagtt gcactggtag
     5521 gtgcggtact ggctacgtta actgcatgta ctggtcatat tgaaaaccgt gataagaact
     5581 gctcttacga ctacctgctg cacccagcta tttctatttc taaaatcatt ggcggttgcg
     5641 gtcctactgc acagtaagtc tctgacagaa attggctgat gctgatttaa ttgcctgacg
     5701 ccctcgggat tttccgaggg cgtatttttt ctccatactc ttcgaaaaac atcgttccca
     5761 gaattaaacg tcggcaatac tctcgcgcaa aatccgcaat accgtctctt caccgctgcg
     5821 atttgggtta atacgaatcg cgtaatgttc gagttgcgga ttcgcctggc gaaacgttcc
     5881 ggaaagtcga taaaaaagtg gcggaatttc atatttcgac tccgcgccca ccggatacgg
     5941 caacgcgccg cgtttctgcg cctcctccag caccctggcg gcaatcggct gatgaaactc
     6001 gacaatcaac accttcgact gtgcattggc aatgacggcg cttttcactt ccggaactgc
     6061 accaccgttg agcaaggcca gcaaccgctc agataccccc gcctgcaccg cgtgcatcac
     6121 tggcgcaaac accagcccac gcaagacttc cagcgcctga gcgccctgaa tctggctgcc
     6181 gccggaatag agcgtggcgc gaatacggtt aataacatca gcatcgccta ccaccgcgcc
     6241 aacaccctct ggcccaaata gcttgaagca ggaaaatgtc gagacattcg ccccgcattc
     6301 acagccaatg ctcgccacct tcatcaccgc atagttgtca tcggttaaga ctggaacccc
     6361 tgccgcgcac aacgttgcca gcacatctgc cagtacatag ctgtcctgcg gctgctggcg
     6421 cgtatgctgc accagcgccg catccggttg ttgctcgtcg acgacctgct taagtgccga
     6481 caggtcattg aaattagcag taataagcgt cagccccatc tgctcaataa tgacctgagt
     6541 cgtcgggtaa accggcgcgt catgcaccag aagacgctgc cccggtttga gcaaagccgc
     6601 caacgccgca cggatcgcgc cagtacccgc gccctgtacc agcgccgcag cctgtgcgtg
     6661 aaacgcgtca gccagcacct gttccacacg ctgggtaatg cgcggttgat tcagtcccgg
     6721 cgttaatccc aaatcaccgc aggtaagaaa ttcgctacca ggaaaatggc gacaaatgct
     6781 atccaccagc gcaaactgct tttgctgcgc ctcaataatc gtcaggcttt gcagaggaaa
     6841 cgtcttcata ggtgccttcc ttaagccgga acgaacaggc caagccagta aagaacattc
     6901 agcagaatac cggtgatcat tactgccacg accggtgccg ccattttctg taccggacgg
     6961 cccagggatt cgttgaggaa gtaaatggca actgcgatag agaatccggt ataacccgcc
     7021 attttaattg ctgcgaaaat cgaaccgacc agcaacgcca cttccatcag catattcatg
     7081 gcgttacgga tgttatccga cgcattacgc accgacgggt agcgccccag ccatttgccg
     7141 atcgaacgaa gcagcaagac ttccgccgaa ataaccactg cgcctaatac cgctgcaacc
     7201 atcggattcg gcgagagata gcccaccgca taaacaaagg taaagcccgc aactgcatat
     7261 acgccggtgg ctaacgcggt ggtggcaatc aacggcacaa aacccagtcc gcgcataaat
     7321 tccgccagag ctgcctggtt gattagtgtt tgcgattgtt ccggcgttac gcctgcggag
     7381 tacgctttct ccagagtgaa gatcgacact tcactaccgg cgaaaatctt catgctggca
     7441 acggcggcaa tcaatgctcc cacgatggcg atatacggta agtttttgat aatccgtgac
     7501 gtgcgttctt caaacaccga aagcccgctg gcatcaatgt cattttcatc acgatgacgc
     7561 aggtcgtgag ttatcgcgat ccccagcagc atcaccatac caataaagat ttcgatggat
     7621 tcagggttaa gatgtgggaa atagtgcacg acgaccacac gggtcatcag taccaccacg
     7681 gcggcgatca gactttgctt ccagccaaac tggtagaaaa tcgccaccag cgggaagagt
     7741 gcaaaagctg aaaccaccgg cgagcttaat tccccgaggc tacctaatac atccaccggt
     7801 agcgcggtca gcagctggtt tactggcaac agacaggtga ggatcaacac gccccagata
     7861 gcgccaagac caaacgccat caggctgttt atcgccagta cgccgaggat atcggtagga
     7921 agaaagagta accatgcgtt gagcagcccg gttttcaggg taaaagagat ccccaccgag
     7981 gccacaaaac caatgctcag accaaaagcg atactccccg cctcgcgacg gttcatatag
     8041 ccttcaatca gttgtggcag gatcgggcgg ataccgtcat gaaaaacggc cgccgagcga
     8101 tgcgccagaa gcgatgtcat acccgtcagg cacgccacca cgataatctg aatatacaga
     8161 tccatagtcg tgccttttat ttcagatggt taatcagcat cggaatcgcg tgttcaacgt
     8221 gctcaacgga aaggccaaac gccacttttc cttcagcgat cattttggcg atatgttcgt
     8281 ctttcgcttt aatgcccggt ttggcaatgg tgcaactttt gttatagcca atcaccgcga
     8341 tggcaatcga caatgccgcg cccgcaccgg tattacacgc accgatgtag taatccagtt
     8401 gcccggattt cactttcatt gccgcttcca tgtcgttgtg aatgaaaact tcgaaacagc
     8461 caggagccgt cgcttcaatg gtttttttaa tctgctcacg ctgtaagcct gcaacaccaa
     8521 tctttttcat gagtctgtcc ttattggaaa aattgagagg gattttcacg taacatcaca
     8581 tccacatcgg cctgactgaa tcctgactgg cgcaattgcg gaataaaggt ggtcaataaa
     8641 aagtcatagc cataaccacc gttggctttt aaatgagagc gccgcgtaat atccatcgac
     8701 agcatgacgc ggttcagcaa cccacggtca cgtagcgcat ggagcatcgc aatccgcttt
     8761 tcgtccgggt agtaactgtt cttgccgatg gtgtcgaact gcacatacgc gccgagatcg
     8821 atcatcttca aaatgttgtc gagattgtct ttcagatcgc agtggccgac ggtgacgcgc
     8881 gaaagatcaa ctccgtgggc ttgcaacaga gccagttgct ccagccccat ggtgctaaaa
     8941 gaggtatgcg tggagatcgg acgtccggtc tggttatgtg ccagcgcggc ggcaataaac
     9001 accttctctt ccagcggcgt aatcttccct tcgctggagc cgatctccgc gatgatcccg
     9061 gctttcagct ccgtgccatc gataccctgc tcaatttcat cgaccatctc ctgcgccagt
     9121 tcctgcacgc tgcgggtcgc cacatgttcc gggaaaaacg cgtcctggta ataaccggta
     9181 caggccacca cgttgatccc ggtttcgcgc attacatcga gcataaattg tgcattgcgc
     9241 cccatgtaac ggttggtcat ctcaatcaca ttacgcacac ccagtgccat caggtcgttc
     9301 atctcctggc aaatgaacgc atactgatca aggcggcagt ccacgttgtt tttaaagccg
     9361 gagagatcaa tatgcagatg ctcatgggcc agggtgtagc ccgttgaatc aaaactcata
     9421 gggtgtctcc tgcaaaccgg agggaggaaa gaaaagagcg accattttgt ggcggtggcg
     9481 cacggaaaaa ttcacacacg gtagcgccca catcggagag cgtggtgcga acaccaagct
     9541 gcgtggcagc caggccttgc tgataaacca gcaccggcac gacttcgcgg gtatggtggc
     9601 tgtgaccgat tgtcggatcg ttaccgtgat ccgccatcac gaccaggcaa tcatctggct
     9661 gcatcgtctc aaccaggaga gcaagattac ggtcaacgac ctgcaaacgt tcggcataac
     9721 gtgcgacgtc ttctgcgtga ccagcgaggt cggtttcctg aatgttggtg caaataaacg
     9781 ctgtctgatg ggtgataaat tcgtcgaggg tgatatccat aatccgctgg ctatccacca
     9841 ggttttgcca gctcacgcca taaggattgt tgacgatatc tgccacctta cccaccagca
     9901 cggttggcac gcctgcttca tacagttttt gtggcacctg cactttttca tcgacgccat
     9961 agcccatatg cacgacctgg aaaccgttgt cataagcgcc agaacgcggc gcgttgatgc
    10021 caataaagcg cccttctttg ctttctgcgg catcgagaat gcgttgactg tcggttaaca
    10081 ggccgccaaa tgtaatgacc cgcccgaccg gtacctgctc acgcacgata cgaccaattt
    10141 tgattgcgtc gtcaaaagag accacagaga gattggcggt gatgttatag acctggccta
    10201 aatccgcctc gagattatcg ccaatcgcaa ccgcctgatt gacccacaga aattgcaact
    10261 cttcgccacg gcgctccacc tgccaagcgg cggaaactaa tgcctgctca acacggtcaa
    10321 tcacatcgcg aaaaggcatc cgcagcggcg gtaacgggcg cgtgcctaaa atttcctgat
    10381 gccccataaa ggtatcgcca ccttcatgtt gcagctctgc cacaccccag gttgcggagt
    10441 ctgacggctg catatcacct ggcgcataac ccaatgcgtt gattagcccc aacttctcca
    10501 gcgttggtag ctgcaaatgc ggcagctggc tcaggatgtg accacaagta ttcgccccgg
    10561 catcctgtgg acgcaccagc gtgacatctt tcattgcgcc tacgccaaag ctatcaatca
    10621 ctaacaccac aaatcgcgcc attacgcccc cagagagttt ccaagactgt cataacgacc
    10681 gacgatttcc ggttcgccac ggtgaatacc ggacagcaac accacatcgc tacgggtgac
    10741 aaaaatctgc gtgcgaaaac agagcactac tgcactgctt accggaaact cgcctgccag
    10801 cggcagggtg tagtcgatac tgctgtcatc cacagttttg agattggttt cagtaatctt
    10861 ttgattttct ggcgtaaaca ccagcgcatg ttgcgcgtga ccacgacggt agtaaccgcc
    10921 gccgtagcag tagctgtcgc cacggaaatg atgggagatt tcacttaacc agagcatcgc
    10981 gatacgttca ggctgatcgc cctgctggtt tgccggaata gtgcccgtca gcgcatgacc
    11041 gggttcggca tgagtcacac cgtattccgc cagcaatggc agcgaagtgc agctggtcgc
    11101 tgaaggcgcg ttcagttgct caatcgcaat accagatttc gccagttgat cccgtgcttg
    11161 taccagcgtg tgaagattcg gtgtcggcaa aactttcccg acagcttcat cccaaagcag
    11221 gcaagggaaa tgggtaagtc cagctaaatg cagccccggc agtttcttaa tttcagcaac
    11281 cacctcgtgc agcgaatgct gtacaaaacc gctctcctgc cccggataaa gaaaatcatc
    11341 gtcgctataa actttgagca gcacagactg cacacgtccg gccttcaccg ctgccgcaga
    11401 aacttcccgc gctttgtcga gagtaaacac ggtgatgacg tcggttccct gtgcaacggc
    11461 gtcaaccacc tgatgacaag ggatttgtac caaatgcccc tgatgcgcca ccggcaaacc
    11521 agcgcggcgc atgactcgcg cctctttgta atccaccgcc acaatgccgc tgtagcctaa
    11581 tgccagcagt ttttccgcca gccacggatt acgaccaaac tgcttggtca tcagatacag
    11641 ttcaatgccg taaagccgcg ccgtctcaat cagccgctta ccgttttcca gtatctgatc
    11701 cacgtcgatc acccagctgt ccggggcgat cttgcccttt tgccacaaac ttagtgcggc
    11761 ggaaattagc gccgggttct ggcgtttcaa tgcttctaca aacatcttgt tgcctcgttt
    11821 ctgttccttg aattaaatat tcattttttt gaatatttag gttgtgcgac gtggatttgt
    11881 cgggagcttc aaacctcttc gttagcagcc atccataatc cataaaggtt ggccagcaaa
    11941 tagccttctt cacacgggtt aacttccagt gcaaattcct tcaacaacac ctgatgcaat
    12001 tgcacaacgg cttgccagtg gctggattgc gccagttctg ccagcaattc gttatccagc
    12061 ggctctattt cttcaccgcg gcgactgcgc atcagtgcgc tcgccatatg tgtcatcgcc
    12121 atcgttcctt gctcactgcg cactggcaga tggaactctg tttccagtac gttgacgacc
    12181 tgcatcatgc ctttgcagat gtccttatca ataacgcctg cctcgcaaag caggttgagt
    12241 ctggtttcca tttcagatgc ctttcattta ataactgggt tcctgttccc cactcaccac
    12301 tcgttgttga tgggcaagca gggcctgttt atcaaccact gcacgcagca gttgttgcat
    12361 tgggtaatca tcgactcgcg tcaggaccac ggcttcggtg gcctgtaaaa atcgcggatc
    12421 gtctgtgagc ggcgtcgctt ctaatcccag catggtcagt tcgttttccg ccaccacgtt
    12481 ccagatcacc gcatcgacat cgcctttaac aatgcgttgt aaactctcgt gataagagag
    12541 atcgacacgt tccacatcac tatcgccaaa aaagacatcg gtcatgattt tctgatccgc
    12601 cgaacggtta tccagcccca cgcgcttcac gtttgcggac tcgcctttac ggcaaatcaa
    12661 ctggtgctcg ccaacgtagg tgtgcggccc caactccagc gcgaggcata agcctttttg
    12721 cgtgagataa ctttccgccg ccagtcggga aacaaccgcc atgtcataca cgccgttaag
    12781 taaacactcc acgcgaatat ccgcgccgcg catatgcgca tagtaaaaag gaataccatc
    12841 aaactgagct ttcaatccgc tcgccaggcc ttcgtacaaa cgggtatagg gcaagggcat
    12901 cgcgcacacc acattgttga tatctacatg agtcagcaat gctttgttat ccatctcgac
    12961 cagataactg ccattgcgcc cacggcgttc aatccgtatc gctccgcttg attccagcgt
    13021 tttcaacgcg gcctgcgtca ggccaaccga tgaacggcat tcagttgcca gctcatctat
    13081 ggttttcagt cgattaccgc acttttcacc caacaaataa cgggccagtg tcgtgataac
    13141 gacgccttct tttttgataa acgttcgacg cataatatat tttcaataaa atgaatgttt
    13201 atatcttcat taaaatgaag ataagtggca actgtgagat gtggaaacgg cgaggtgctt
    13261 cacatttttt cggattattg caaatgagga taaaaaaacc gggtttcccc ggtttttggc
    13321 attaatgtta aattacggct tcgccacaaa accaatcgct tcgtacaccg ctttcagcgt
    13381 acgagaagcg tgtgcactgg ctttttccgc gccgtctttc atcacctgtt gcaggaaggc
    13441 ttcatcgttg cggaaacggt gataacgttc ctgcaattca gtcagcatac cggaaacggc
    13501 atcagccact tcgcctttga gatgaccata catcttgcct tcgaactgtt tttccagttc
    13561 cgggatgctc tggcccgtta ccgcagaaag gatatccagc aggttggaaa cgcccgcttt
    13621 gttctgcaca tcgtagcgaa ctaccggcgg ctcgtcggag tcagtgaccg cacgtttgat
    13681 tttcttcact accgatttcg gatcttccag caggccgata acgttattgc ggttatcgtc
    13741 agacttggac atctttttgg tcggctccag cagcgacatt acgcgcgcgc cggatttcgg
    13801 aataaacggc tccggcactt taaagatctc gccatacagc gcgttgaaac gctgggcgat
    13861 atcgcggctc agttccaggt gctgtttctg gtcttcaccc accggtacca gattagtttg
    13921 atacagcagg atgtccgcag ccatcagcac cggatagtca aacagaccag cattgatgtt
    13981 ctcggcataa cgcgcagatt tatctttaaa ctgcgtcatg cggctcagtt cgccgaagta
    14041 ggtatagcag ttcagtgccc agcctaactg tgcatgttcc ggcacgtggg actgaacaaa
    14101 aatggtgctt ttctcaggat cgataccaca agccagatac aaggccagcg tatccagcgt
    14161 cgctttacgc agcttctgtg catcctggcg cacggtgatc gcgtgttggt caacgataca
    14221 gtaaatgcaa tggtagtcat cctgcatgtt tacccactga cgcagcgcac ccatgtagtt
    14281 accaatggtc aattcacctg agggctgtgc gccactaaaa acgatgggct tagtcatttt
    14341 tcgattcctg attttcgcta tgcggaagcc ctaatgcggg cagaaggtca tttatagact
    14401 gataaattac atcaggctgg ctgagatcga tagcctcgcc gtagttatat ccgtaggtta
    14461 agccaactga tgggcaacct gccgcttttg ctgcctgaat atcattgcgt gagtcgccaa
    14521 caaacagcat ctgttgtgga gcaattccca tccgctcagc caccagtaac agcgggtccg
    14581 gatgcggttt tttgttttgc acatcatcac caccaattac cacgctgaag tatttggcga
    14641 tatctaaggc ttcgagcagc ggcgcgacga acggcgtcgg tttgttggtg accagaccta
    14701 gcggcaggcc tttagcctgc aatgcgccca gcgtatcggc aacgtgcggg aacaaaaacg
    14761 tcccctcttc ggcaacctcg ccatagtagc gatcgaacag tttacgcaga atacgtactt
    14821 gttcttctgc cggaatgtcg tcatcaacgg gcggtttacc cattgtttta cgcagagtcg
    14881 cacgttcctg acgcgcccag gtcaatgcgc gctccatcag aacatctgcg ccgttaccaa
    14941 tccaggttat aacgcgttct tcacctgcga cgggcaactc cagcgcatac agcgccatat
    15001 ctactgcggt agccaagcca ggagcactgt ccaccagcgt accgtcgaga tcaaaagcga
    15061 cgccgcgaat atcttcaaac ttattcatga cttacctttg ccagttcact gcgcatttca
    15121 tcaatgactt ttttgtagtc tggctggtcg aagattgccg aaccagcaac aaacatatcc
    15181 gcgcccgccg cagcgatttc gccaatgttg ttcaccttca cgccaccgtc cacttccagt
    15241 cgaatgtcaa agccagactc gtcgatacga cgacgtactt cgcgcagttt atccagtgtt
    15301 tgaagaatga aagactgacc gccgaaacca ggattaacgg acatcagcag gatcacatcc
    15361 agcttatcca tcacgtaatc cagatagctc agcggtgtcg ccgggttaaa taccagcccc
    15421 gctttacagc cattttcttt aatcagttgc agcgtgcggt caacatgctc ggaggcttct
    15481 ggatgaaagg taatgatgct ggcaccagcg gcagcgaaat caggcacaat gcgatcgacg
    15541 ggtttcacca tcagatgtac gtcgataggg gcggtaatgc cgtagttacg caaggatttc
    15601 agcaccattg gcccaatcgt cagattggga acatagtggt tatccatgac gtcaaaatgc
    15661 acgacatcag cgccagctgc cagggctttt gcggtatctt cacccaggcg ggcaaaatca
    15721 gccgacagaa ttgagggggc aatcaaatac tgtttcatcc gcttctcctt gagaattatt
    15781 ttttcgcggg tgaaacgact cctggtttgt acaaagccag cagttcgtcc acctttttac
    15841 gtgtgccgcc gttgctgctt atactgcgtc gaactttgac gacatgcaat tttgcgcgct
    15901 gataccactc acgcgttaac atcgtatcgt gattggagat cagcacagga atatggcgat
    15961 caaccagacc ttcggcgatc tccgccagat gcgcttgttg ttcaagcgta aaactgtttg
    16021 tgtgatacgc cgtaaagttg gcggtcgcag acagcggtgc ataaggcgga tcgcaataga
    16081 cgacggatgc atcatctgcg cgtgccatgc tatcggcgta agactcacaa tagaaaaagg
    16141 cattctgcgc tttttcagcg aagtgataca actctgcttc cgggaaatag ggttttttgt
    16201 agcggccaaa cggcacgtta aactcaccgc gcagattgta acgacacagg ccgttgtaac
    16261 cgtagcggtt caaatataaa aacagtaccg cccgacggaa cggatcctgg cttttgttga
    16321 actcttcgcg gaactgatag taaacctcgg cgcaatttgt ttcgggaaca aacagctcgc
    16381 gtgcggcctg tacgtactca tcagtacgca ttttcacaat gttatagaga ctgatcaggt
    16441 cgctattgat atcggcaagg atataacgag aaaagtcggt gttgagaaac accgacccgg
    16501 cacctacaaa aggctcaacc agacattcgc ccttgggcaa atgccgttta atatcatcaa
    16561 gcaggggata cttgccccct gcccacttca aaaaagcgcg atttttcttc atgctgacta
    16621 actaattaca ccttctccgg ctgtggagaa agctccgaca gcatccagcg cttcaggcaa
    16681 ctcccgcgat gataaaccat tgcgggagat aaccttgatt acttcagatc ggcctgtacc
    16741 tgacgcagcg gtttcgccca cgggtttttg gcctggacat cggctggcaa tgtagatacc
    16801 gcttttttcg cctcttcttt cgaagcgtac acgccagaaa ccaggacata ccacggctga
    16861 ccattacgcg tcgtttcata gacaacgtag tttttcagat tctctttctt cgcccaaccg
    16921 ttcaggttgt cgtagttaga ggaactgctc agctgcagag tgtaatggct ggacggtgcc
    16981 gatttcaacg aacccacatt acctgcggtc ttccctccag cggctggtgt tgccgtggtt
    17041 tgcgccgggg atgccgtctg tactggagcc gtagttgcgg tctcttttgg tgctggcgta
    17101 gaggtcgcag ccggtgcctt cgtgcttgcc acaggagcag ctggttcagt acgcttcggc
    17161 gtctgtgcta ccggcttcgg ctccgttttc acggttgctt gcggtttttt cggttcaatc
    17221 accgcctgct ggcgagctgg acgcgtagtg gccggacgtt cagcggtttg cgttttcgcc
    17281 gtgtcacgcg atgcattgcc attgcgaaca ggcgcgaccg tcgcgggttc agtcggcaac
    17341 gtggaattga ccgccacatt attcaactgt tgctgatttt gtggctgggt cagcgcattg
    17401 ttcaggtcac cctgcacttc aacacgttgt tgaccatccg ttgccgccgg ggtttgccct
    17461 tgagtcggcg tagaagagat cggcggcaga aaaacatcct gctgagtatt ttccgcagac
    17521 gtggttcccg gcgctggctg cacaccattc gcctgatcgg tcgcattgcc tgcaagatca
    17581 atactcttct cgccagacgc ggtttgatcg ctggaagagg tcgagggggc ttttagcgca
    17641 gaaccgatac cgatgatcaa cagtaggaga accagaatgc cgacccccat catcatatac
    17701 tgacgagaag cgggtttact ggctgctttt ttgcgcttac gcggacgacg ctctacgcgc
    17761 tcttcatcca cgatttcatc ttcggattcg tcaatttctt cttcgatttc cggctcatca
    17821 ttgcgctctt tttgcgcacg agtcggacgg cgatcgtcag tgtcatcaag ttcaatatca
    17881 tcaaaattga tctgcggttc gccacgttca gtacgctcag aacgttcaga agattgacga
    17941 gaacgaccag tacgacgatc gctgggatcg ggtttcagct cgtcttctgg tttgaattca
    18001 tccatttaac accccactaa aaggttaatg cttaccacgt tgcaattaac ctgaagctaa
    18061 tagaccgctt gataagcggc ctgacctttc ttgttgttac gctgattgac aatcggcaat
    18121 ggcgttaaga acaagctcgt gcgaaacgcc gctgcgaact tcactcttac caattgccaa
    18181 cggaagaatt aagcgcatct ctcccgcaag gactttcttg tcacgcagca tatgcggtaa
    18241 atacgcctgc gcagacattt cgcgcggccc attgaccggt aacccagccc gcgtgagcag
    18301 ggttataata cgctgcgttt cggcagaact aaactgcccg agacgttccg acgtccgcgc
    18361 cgccatcacc atacccgcag caaccgcttc accgtgtaac caattgccat accccatttc
    18421 agcttcaatg gcatgaccaa aggtgtgtcc cagattcagt aaagcacgta acccggtttc
    18481 gcgctcgtcg gcggcgacaa cttctgcctt cagttcacaa caacggcgaa tacagtacgc
    18541 cattgccgga ccgtccagac gcaacaacgc atccagattc tcttccagcc agttaaaaaa
    18601 cgcaccgtca agaataatgc cgtatttgat gacttctgcc agccccgacg ctaactcacg
    18661 cgggggaagc gttttcagac agtcgagatc caccaccact gaagcaggct ggtagaacgc
    18721 gccaatcatg tttttaccga ggggatggtt gaccgcagtt ttgccgccaa cggaggaatc
    18781 gacctgcgac agtaacgtcg tcgggacttg aatgaaacgt acaccgcgct gataactcgc
    18841 cgccgcaaag ccggtcagat cgcccactac gccgccgcca agcgccacca gcgtagtatc
    18901 gcgaccatgc ggcttttgta acaacgccgt aaagacggta tcgagtacag ccaggctttt
    18961 atactgctcg ccgtcaggga ggataacgct atcgacgtta acacccgcct gttcaagtac
    19021 gccgcggacc ttatcgagat acagaggagc cagggtttcg ttggtaacca acatgacctg
    19081 ctcgcccgat ttcagcggta agaatgaagc tggttcatta aacaaaccag atgcgatggt
    19141 aattgggtaa ctacgttccc cgagagtaac gacaatcctc tccataacgc gacatccacc
    19201 ttaattactg tacccgcaga cgagtgtata taaagccaga attagttgct ttccagcatg
    19261 tgaataatct ggtttgcgac cactttagcg ctttgatcat cagtacgaat ggtcacgtcg
    19321 gcaatctctt catacagcgg attgcgttca ttggccaacg cttccagaac ttcacgcggc
    19381 ggtgtttcaa cgtgcagcaa cgggcgtttt ttatcacgct gcgtgcgtgc aagttgcttt
    19441 tcgatggtcg tttcaagata aacgacaacg ccacgtgcgg aaagacggtt acgcgtttcg
    19501 cgggatttca cagagccgcc gccagtagcc agcacaatac cctgtttctc ggtcaactca
    19561 ttgatgacct tttcttcgcg atcgcggaag ccttcttcgc cttctaaatc gaaaacccag
    19621 cccacatcag ctccggttcg tttctcaatc tcttgatcgg aatcgtaaaa ttccatattg
    19681 agttgttgag ctaactggcg cccaatagtg ctttttccgg cacccatagg cccaaccaga
    19741 aagatattgc gtttctctgc cattttttcg gtactactaa gactattcgt taatgataaa
    19801 cccgcttcgc tcagagagcg ccgcaggaca tgaactgaaa cctcataaga tattgcgaga
    19861 gtcagactga aaattatctc aatactccag cgggtttggc aactgaataa atcacccatc
    19921 cctctgcata tctggtcgct gcaagcgcgc tgccttgcta ccaccgctct ggcgataaat
    19981 caccgggtaa gattagcgta aaaaagacag caaaatgccg cctgaatgat aaatcatcat
    20041 catggaacgc aggcagcgaa gagcaccaac tctcaaatcg gtactccttg tatgctaaat
    20101 acctgcgcgc gtcaaataga tgaaacacgt tcagcgtaaa aacattaccg cttttacggc
    20161 tgtttactca ctggaaacca gtcgtggcgt gataaacacc actaactcgc gtcgttcatc
    20221 ttcttttccg tcatgacgaa ataattgccc gaaccaggga atgtcgccaa gcaacggtac
    20281 gctatcctga cccgatttat ttttacgggt aaaaatgccg cccagcgcca acgtttctcc
    20341 gcttttgacc tcgacctgcg tttcgatctc ctgcttatca atcgccagca cttcgccatc
    20401 tgcctgctgt agcacctgcc ccggaacgtt ctggctgatg tgtaatttca gccggatgcg
    20461 acctttttgt aacaccgtgg gcgtgacctc catccccagg acggcctctt taaattccac
    20521 cgacgtcgcg ccactttccc cgctggaaac ctgatatgga atttcgctcc cctgtttaat
    20581 gctggcaggc tgaagatgtg aggccagcag acgcggactg gcgataatat ccagctgctg
    20641 tttttgttcg agcgcggaaa gctcaagatc cagtaaacgt ccgttgatgc gtccaatgtt
    20701 aaaaccgaca tgcgttgtcg ccgtcgctac ggagaggtcg ctgccaagcg tggtgacttg
    20761 cccaacgcca ccagcttgtt gcgcatcagc caacgtccat ttcacgccta actcacgcaa
    20821 acttttttca ttaatggtga caatatgcgc cgagagctca acctgcccga ccggcagatc
    20881 catttgcgct acccactgtt caagcgtgct taacgccgtt ttgttatctc gcagcaaaag
    20941 gcgattggtg cgtttatcga cggtcatact ccctttggca ctcagtagct tctccccagc
    21001 tttcgccagc tctccggcgt cggcgtattg cagagtaata ttgcgatttt ccagcggcag
    21061 atttgcctgc gcccgcgcct gctccgcttc ctgacgggcg atattgtcat tctgccaggc
    21121 aatggaatgc actgagagaa tgttgccctc ctggcgcgtt atcagtccgg cgcttttcac
    21181 tacagtttgt agtgcctgct tccagggaac atctgttaga tgtaacgaca ccgtaccgct
    21241 gacgtctggc gacaccacca ggttcaactt ctcctgttca gccagcgcct gcaacacctg
    21301 agctaccgga acgtcatcca ccatcagtgt cactttttgc ggctttgccg cctgtacgcc
    21361 gggtatcagc atcaacagta gtgcggctat ccattgcttc atttgtatct ccttgccgtt
    21421 gccacaacca ttgtggcggt tcgcagtttg tcccggtacc cagcgttagt acgtctggcg
    21481 tcagctgtaa aattgtccag ccgttttcca gcacatcgtt ttgctgcacc cgtcgccatt
    21541 tcttttgccc gtcttttatt acaccgatga tgcgctcgcc tcgccctact atcccctgat
    21601 agcgccactg gctaagttcg ctaatccggc atagatcttc cggcggttta aaagggtcac
    21661 gcataccggt taaaaggcac aatgcaatac ctgccaacaa ccagcgttta cccctcatgc
    21721 ggcgtctcca gttgtagcgt gaacaaaaga tcatcacctt ccacgcttaa cgaaaaacgg
    21781 ctcacgctga cgttgcgctc tgccagccgt gtaaatgccg acggcactgc ttcccacagc
    21841 gttttcaacg ccaactcacc tccctgcgcg gatggatgcc aggaaaccag ttgcgcgccg
    21901 ggcaactgaa aatccagtgg cgaaaagggc agcgtttttt cttcgctgaa gggagtggtg
    21961 tctaccaggc gatacagtgc ggcccactgc tggtgatgac tcgcccgtag tcgaattaat
    22021 gcgtcgctct cttcctggtg tgtcgatgac agaaaaatga gcgtaactaa catcatcaac
    22081 cagaatgccc agcaaagctg gcggaggcgg ggtgatgcgg cgaaccacca gtcaaagagc
    22141 atgtccatcg ctaaccttcc ttgttaactg atactcaaat tgccagcgtc cctgcgcatc
    22201 ctgctgcgtg cccccccgct gattgagatg aaaaaaagca tcctgacaga gtgacgtttc
    22261 cagcgcgttt aacgcggtaa tgcttgttgt cagccccttg atctccagcg ttccctgctg
    22321 ccagcttatc gttgtcagcc aggcgtgctc gggtaaaagc gccgccagtg cttccagcgc
    22381 agattgccag tcgcgggtaa attgtcgctg gcgctgcctt tgcaaacgct gttcgcgtaa
    22441 ctgctgttgc tccagcaaac gtggtttcgt tatctgtaag ctgtgggcaa gttgttgttc
    22501 cgcctgaagc aaaacggcgt ttacgcgtgc ttcggcgttg cttgtcagac gcagtattag
    22561 cgtaatcccg acggccagca gcagaggcgc aacgaacatc agcaaccaga aacgcagaaa
    22621 agcggtccgg cgttgctgtc gccagggcaa aaaattaatt ggcgggttca tcagttcgcc
    22681 ttccctagcg ccagccccag cgcgatggca aagtctccac ctggcggcgg tagcggcggc
    22741 tgacgaacag aaacggcctc ccagggatca aatccgcctt cgccacatag cgcgacgctt
    22801 tcgggatcaa cggataacgc tgccgccagc tccttcgcgc tagtcatccc caccgccagt
    22861 ttgcgccccc agcgatagcg cgtcgcccac agccactgtt cgttatcacg ccaggccaga
    22921 cattgctgat gagaaggtaa aaaaggcagg aatcgctgta atgcactggc atccggggtg
    22981 atcgcgctaa catgaacacg caacctttct gccagagtaa gcagcgttgc cagctctttg
    23041 ctttgcgcgg cagtcacgtt ataggcggga ctgagtgagt cttcgctgta atcgaagcgc
    23101 agggagtccg gatccatatc cagttcacgg gccatcgtcc cggacagcca ggccgtttgc
    23161 tcccgctcac caagggacat cgacgggcgc ggaaatgacc gctgtaatgt gcgactggcg
    23221 ggaaacgcca acataatgtg atgacgctgc ggcagttcgc ggctccacgg taacaacgtg
    23281 ttagccagcc gctgcgcatc aacaatccgc ccatctttga taatgtcatt ctccagcggc
    23341 aaccgccacc agcgttgcaa aaagcattct tttgcgcccc gcacgatcgc aaccgctacc
    23401 gcttcttgct gttgtaaatg caaaccaatt tgccagatct taaatgccat tgtgatgatc
    23461 tccttatcac ccgtcactct gacgggtata tcaatgcgtc tggcttgcct ttatactacc
    23521 gcgcgtttgt ttataaactg cccaaatgaa actaaatggg aaatttccag tgaagttcgt
    23581 aaagtatttt ttgatccttg cagtctgttg cattctgctg ggagcaggct cgatttatgg
    23641 cctataccgc tacatcgagc cacaactgcc ggatgtggcg acattaaaag atgttcgcct
    23701 gcaaattccg atgcagattt acagcgccga tggcgagctg attgctcaat acggtgagaa
    23761 acgtcgtatt ccggttacgt tggatcaaat cccgccggag atggtgaaag cctttatcgc
    23821 gacggaagac agccgcttct acgagcatca cggcgttgac ccggtgggga tcttccgtgc
    23881 ggcaagtgtg gcgctgttct ccggccacgc gtcacaaggg gcgagtacca ttacccagca
    23941 gctggcgaga aacttcttcc tcagtccaga acgcacgctg atgcgtaaga ttaaggaagt
    24001 cttcctcgcg attcgcattg aacagttgct gacgaaagac gagatcctcg agctttatct
    24061 gaacaagatt tacctcggtt accgcgccta tggtgtcggt gctgcggcac aagtctattt
    24121 cggtaaaacg gtcgaccaac tgacgctgaa cgaaatggcg gtgatagccg ggctgccgaa
    24181 agcgccttcc acctttaatc cgctctactc aatggatcgt gccgtcgcgc ggcgtaacgt
    24241 cgtactgtcg cggatgctgg atgaagggta tatcacccaa caacagttcg atcagacacg
    24301 cactgaggcg attaacgcta actatcacgc gccggagatt gctttctctg cgccgtacct
    24361 gagcgaaatg gtgcgccagg agatgtataa ccgttatggc gaaagtgcct atgaagacgg
    24421 ttatcgcatt tacaccacca tcacccgcaa agtacagcag gccgcacagc aggcagtacg
    24481 taataacgtg ctggactacg acatgcgcca cggctatcgc ggcccggcaa atgtgctgtg
    24541 gaaagtgggc gaatcggcgt gggataacaa caagattacc gatacgttga aggcgctgcc
    24601 gacctatggt ccgctgctgc ctgccgcagt caccagcgcc aatcctcagg aagcgacggc
    24661 gatgctggcg gacgggtcga ccgtcgcatt gagtatggaa ggcgttcgct gggcgcgtcc
    24721 ttaccgttcg gatactcagc agggaccgac gccgcgtaaa gtgaccgatg ttttgcaaac
    24781 gggtcagcaa atctgggttc gtcaggttgg cgatgcatgg tggctggcac aagtgccgga
    24841 agtgaactcg gcgctggtgt cgatcaatcc gcaaaacggt gccgttatgg cgctggtcgg
    24901 tggctttgat ttcaatcaga gcaagtttaa ccgcgccacc caggcactgc gtcaggtggg
    24961 ttccaacatc aaaccgttcc tctacaccgc ggcgatggat aaaggtctga cgctggcaag
    25021 tatgttgaac gatgtgccaa tttcccgctg ggatgcaggt gccggttctg actggcagcc
    25081 gaagaactca ccaccgcagt atgccggtcc aattcgctta cgtcagggac tgggccagtc
    25141 gaaaaacgtg gtgatggtac gcgcaatgcg ggcgatgggc gtcgactacg ctgcagaata
    25201 tctgcaacgc ttcggcttcc cggcgcaaaa cattgtccac accgaatcgc tggcgctggg
    25261 ttcagcgtcc ttcaccccaa tgcaggtggc gcgcggctac gcggtaatgg cgaacggcgg
    25321 cttcctggtg gacccgtggt ttatcagcaa aattgaaaac gatcagggcg gcgtgatttt
    25381 cgaagcgaaa ccgaaagtag cctgcccgga atgcgatatt ccggtgattt acggtgatac
    25441 gcagaaatcg aacgtgctgg aaaataacga tgttgaagat gtcgctatct cccgcgagca
    25501 gcagaatgtt tctgtgccaa tgccgcagct ggagcaggca aatcaggcgt tagtggcgaa
    25561 gactggcgcg caggagtacg caccgcacgt catcaacaca ccgctggcat tcctgattaa
    25621 gagtgccttg aacaccaata tttttggtga accaggctgg cagggtactg gctggcgagc
    25681 aggtcgtgat ttacaacggc atgatatagg cggaaaaacg ggtaccacta acagttcgaa
    25741 agatgcgtgg ttctcgggtt acggtccggg cgttgtgacc tcggtctgga ttggctttga
    25801 tgatcaccgt cgtaatctcg gtcatacaac ggcttccgga gcgattaaag atcagatctc
    25861 aggttacgaa ggcggtgcca agagtgccca acctgcatgg gacgcttata tgaaagccgt
    25921 tcttgaaggt gtgccggagc agccgctgac gccgccgccg ggtattgtga cggtgaatat
    25981 cgatcgcagc accgggcagt tagctaatgg tggcaacagc cgcgaagagt atttcatcga
    26041 aggtacgcag ccgacacaac aggcggtgca cgaggtggga acgaccatta tcgataatgg
    26101 cgaggcacag gaattgttct gattaaaaag gcgcttcggc gcctttttct gtttgctgac
    26161 aaagtgtcac tttatttata ccggatacgg cgtgaacacg ttacccgtct ggcaacatct
    26221 agaaaaatca atatattgca ggagccgcac aggcctgata agcattgtgc atcaggcaaa
    26281 gttcacgcat ttacaaccgc ccctgcccct tcaaccattc gcgcacgagg aaaagcgcgc
    26341 tgacattacg cgcttcgttg aagtcagggt cttccagcaa atccatcata tgcgccagcg
    26401 gccagcgcac ctgtggtagc ggctctggct catcgccttc cagcgattcc ggatagagat
    26461 cttgcgctac cacgatattc attttgctgg aaaagtaaga cggcgccatg ctgagcttct
    26521 tcaaaaaagt cagatcgttc gcaccacatc ccacttcttc ttttagctcg cggttagcgg
    26581 cttcgtagac gctttcaccc ggatcaatta atcctttcga aaaacctaat tcgtaggatt
    26641 ccgttcccac tgcgtattcg cggatcagga tcaggtgatc gtccacaatc ggcacaatca
    26701 tcactgcttc ccggttagtt ggacgcattc gttcataaac acgccgcacg ccattgctga
    26761 actccagatc cacgctttcg acggtaaaca gtcgggaacg ggctacagtt tcaacattca
    26821 gaatggtggg tttttgtaat gatttgctca tcgtgggatc tatgctgtga aatcagcggt
    26881 tattgtgcga tatcggacac gctttcggca atgtgaattg catgttattt acatttatgt
    26941 aacttattaa ataatcatcc tcaaatcaaa ttaaaagtca ataggttgaa ataactccag
    27001 gaatttgctg atattccgcc ttcagagggt ttgctatgat cagcggttac tgtgatgtgc
    27061 ttaatgatgc tcaagttaaa ctccacgctt gccgatagcc aaccgcagaa tcatgtattg
    27121 tgtccggtgc gactgaccac gcctgacaga ctaagtaaga tggggaaagc atgagcacca
    27181 ttgtgatttt tttagctgct ttgctggcct gctcactact tgcgggatgg ctgataaaag
    27241 tgcgatccag gcggcgtcag ctgccctgga ccaacgcctt cgcggatgcg caaacgcgta
    27301 aactcacacc tgaagaacgt agcgccgttg aaaattatct tgagagcctg acgcaggtat
    27361 tacaggtgcc tggcccaacg ggagccagcg cggcaccgat ctctctggcg ctgaatgccg
    27421 aaagcaacaa cgtcatgatg ctgacacacg ctatcacgcg ttacggcatc tctaccgacg
    27481 atccgaataa atggcgttac tacctcgatt cggtagaagt ccacttgccc cctttctggg
    27541 agcagtacat caacgatgag aataccgttg aactgattca taccgattcg ctgccgctgg
    27601 ttatttcact caacggtcat acgctgcagg agtacatgca ggaaacgcgc ggctatgcct
    27661 tgcaacctgt tccgtcaaca caggcgtcga ttcgcgggga agagagtgag caaatcgagc
    27721 tactcaatat tcgcaaagaa acgcatgaag aatatgcgct aagtcgtccg cgcgggctgc
    27781 gcgaagcgtt gctgattgtc gcctccttcc tgatgttctt tttctgcctg attaccccgg
    27841 atgtatttgt tccgtggctg gcaggcggcg cgttactgct gctgggcgca ggactgtggg
    27901 ggctattcgc gcccccggca aaatcctccc tgcgggaaat tcattgtcta cgcggcacac
    27961 cccgtcgttg gggattgttt ggcgaaaacg atcaggaaca gatcaacaat atttcactcg
    28021 gtattatcga cctggtctat cccgcacact ggcagcccta cattgctcag gatcttggtc
    28081 aacaaaccga tatcgatatc tatctcgacc gccacgtagt gcgtcagggg cgatatcttt
    28141 cgctgcatga tgaagtaaaa aactttccgt tacagcactg gctgcgcagt acgattatcg
    28201 ctgcgggctc gctactggtg ctgtttatgc tgttattctg gatcccgctg gatatgccgc
    28261 tgaaattcac cctctcgtgg atgaaaggcg cgcagaccat tgaagccacc agcgtgaaac
    28321 aactggctga cgctggcgtg cgggttggcg atacattgcg tattagcggt acgggaatgt
    28381 gtaatattcg cacttccggt acctggagcg cgaaaaccaa ctcacctttt ttaccgtttg
    28441 actgctcgca gatcatatgg aatgacgccc gctcattgcc attaccagaa tctgaactgg
    28501 tcaacaaagc gacggcattg accgaagcag ttaatcgcca gctgcaccct aaaccggaag
    28561 atgaatctcg cgtcagcgcc tcattacgtt cagcaattca aaaatccggc atggtattgc
    28621 ttgatgattt tggcgacata gtactgaaga cagcggattt atgttctgcc aaagatgact
    28681 gtgtgcgact gaaaaatgcg ctggtcaatc tcggcaacag taaagactgg gacgcgctgg
    28741 taaaacgcgc caacgccggg aaactcgatg gcgtgaatgt gttattacgc ccggtgagtg
    28801 cggaatcact ggataacctg gtggcaacct ccaccgcgcc gtttatcacg catgaaacgg
    28861 cgcgagcggc acaatcacta aacagtccgg cccccggtgg attcctgatt gtcagcgacg
    28921 aaggcagcga ttttgttgat cagccctggc cttcggcatc actttacgac tacccgccgc
    28981 aagaacagtg gaacgctttc cagaaactgg cacaaatgct gatgcatacg ccgtttaacg
    29041 ccgaaggtat cgtcacaaaa atcttcactg acgccaatgg tacgcagcat attggccttc
    29101 atccgatccc ggatcgttcc ggtctgtggc gctatctcag caccactctg ctgctactga
    29161 cgatgctggg tagcgccatt tataatggcg tacaggcctg gcgtcgttac cagcgtcatc
    29221 gtactcgcat gatgaagatt caggcctatt atgaaagctg cctgaaccca caactgatca
    29281 ccccttcaga aagccttatc gaataacacg tttgcgcggc aggttatgct accctgtcgc
    29341 gcaaattgct tcactctgga gatttccctc atgcatatca acattgcctg gcaggacgta
    29401 gataccgttc tgctggatat ggacggcacg ttgctcgacc tcgccttcga taactatttc
    29461 tggcaaaagc tggtgcctga aacatggggc gcgaaaaacg gggttacgcc acaggaagcg
    29521 atggaatata tgcgccagca atatcacgac gtacagcata cgctaaactg gtactgtctt
    29581 gattactgga gtgagcaact gggtctggat atctgtgcga tgaccaccga gatgggaccg
    29641 cgtgccgtac tgcgtgaaga taccattccg tttcttgagg cactgaaagc cagcggtaag
    29701 cagcgaattt tgctcaccaa tgcgcatccg cacaacctgg cggtaaaact tgagcatacc
    29761 ggtctggacg cacaccttga tttattactt tccacccaca catttggtta tccgaaagag
    29821 gatcagcggt tatggcatgc ggtggccgaa gctacgggtc ttaaagctga aagaacactg
    29881 tttattgatg acagcgaagc gattctcgat gctgccgcgc aatttggtat tcgttactgc
    29941 ctcggtgtga ctaatcctga ctccgggatt gccgagaaac agtatcaacg ccatccgtca
    30001 ctgaatgact accgccgcct gatcccctcg ctaatgtgaa ggagacgcca tgaaagaaaa
    30061 acctgctgtt gaggttcgac tggataaatg gctatgggct gcccgttttt ataaaacccg
    30121 cgcgctggcc cgtgaaatga ttgaaggcgg taaggtgcat tacaacgggc agcgcagcaa
    30181 gccgagcaaa atcgtcgagc tgaatgccac gctcactctg cgccagggaa atgacgaacg
    30241 cacggtgatt gtaaaggcga ttactgaaca gcgtcgcccc gccagcgagg cagccttgct
    30301 gtatgaagag actgcggaaa gtgtagagaa acgcgaaaaa atggcgctgg cacgtaaact
    30361 taatgcctta accatgccac acccggaccg acgcccggac aaaaaagagc gccgcgacct
    30421 gttacgattt aaacacggcg acagtgaata actgtcacct gcaagagaga tgattatgcc
    30481 gcaacatgac caattacatc gctatctgtt tgaaaacttt gccgttcgcg gcgaactggt
    30541 aaccgtttcg gaaaccctgc aacagatcct tgagaatcac gattatccgc agcccgttaa
    30601 aaacgtgctg gcagaactgc tggttgcgac cagcctgtta accgctacgc tgaagtttga
    30661 tggtgatatc accgtacagc tgcaaggcga cggtccgatg aatctggcgg ttattaacgg
    30721 taacaacaac cagcagatgc gcggtgtagc gcgcgtgcag ggagaaattc cagaaaatgc
    30781 cgacctgaaa acgctggtcg gcaatggtta cgtggtgatc accatcaccc cgagcgaagg
    30841 cgaacgctat cagggcgtgg tgggtctgga aggtgatacc ctggcggcct gcctggaaga
    30901 ttactttatg cgttctgaac agctgccgac gcgcctgttt attcgcaccg gcgacgtaga
    30961 cggcaaaccg gctgcaggcg gtatgttgtt gcaggtaatg cctgcgcaaa atgcccagca
    31021 ggacgacttt gaccacctgg cgacgctaac cgaaaccatc aaaaccgaag aactgctgac
    31081 tttaccggca aacgaagtgt tgtggcgttt gtatcacgaa gaagaggtga cggtttacga
    31141 tccgcaggat gtggagttca aatgcacctg ctcgcgtgaa cgttgcgccg acgcgctaaa
    31201 aacgctgccg gatgaagaag tcgatagcat cctggcggaa gatggcgaaa ttgacatgca
    31261 ttgtgattac tgcggtaacc actatctgtt caatgcgatg gatattgctg aaatccgcaa
    31321 caacgcgtct ccggcagatc cgcaagttca ttaatgagta tgtccggcag agagggctct
    31381 gccggatttt acgacgtaat ggcctgatgc gctgcgctta ccaggcctat gaaataaatc
    31441 gcaagttatt ttggtcagat acagcgtcgt atccgttaaa agcgttgtca cttacttaag
    31501 tttatttcca gcgtttcacc atctaccgtc agatcgcgcc acgctttagg cctcgtcccc
    31561 agctttccat ccttcgcagc agcgagtaat ttttctttcg ttatttggcg cggaagtaaa
    31621 ctcatatcaa gcgcgtccca ttcttttctg gctgagtcaa agccatagac aatgactctg
    31681 tcatcattaa aagcaaacag gatccgctcc gcctgaccat cactattcag atcttgctcg
    31741 accagtacgc aggcgtcttt ttcaatacag gtcatcacgt tatagcgatc ctggattaag
    31801 gccgaccaga atgtcgcatc cggtttacca gaacctgggg caattaacac attatcggct
    31861 aatacttttt ccgatacctg ttcctgaaga tgttgctctc catctaacgc catcagcaga
    31921 tcccgcgcgc gtttcgggtc tttcataaac ccggcatcgc ttttcagcga ctcaagcgcc
    31981 gcacgtccat agcgaccgct ctgttcgagc atgtagatag ttacctggtc tggcgtgttt
    32041 ttgccgctct gataacgcgc catatgactg ttcacgctaa tgcgcatact gtccagcacc
    32101 ggcgaattaa gaagcaccag cattaccaac accaataacg aaaccgcaaa gttcactttg
    32161 ccctgaagat caaggggatt ttgcccttta cgccagacga tactgacaaa ataccccagt
    32221 gaccatacca gtaacaccag caccgccagc gcgccctgca agcggtcgac agtccagccg
    32281 tactgagcga cccgcagcca taacgcccag gcggcgacga acacatacag cggagcaacc
    32341 agcaaagcgg ttttaatcag gcaacgcaac ggccccgtcc agggaagaga cgctttttgc
    32401 ggatcgcgga caatagccat taagatcaat tgcaaaaagg ccagcgttaa cagcaaccca
    32461 gcggcggaga tgtggcgaga aatcgcgctc aggcccgtaa acggcagggt gataataaac
    32521 atcagggtta gcaatgatac taacggcagc aaccccgtgg cgattaacgt gaacaacttt
    32581 tgaatagagt cgattaaacg tgactgtgta cgcgcgagga tcaccgccag tgcggtaacc
    32641 agacctaacg tgagataaat aaaccagtcg gttgcaaaaa agagcgtttt gaaaaacgtg
    32701 atgccaacaa gtttaaacaa ctcactccac agtaaaagca ccagccacgt caggccattg
    32761 gcgagaaaaa tcaccagtaa tataagtaca ttatgccata ctgactggta aaaatagcga
    32821 tagcggctac tgtcattgcg gatgcgaagg ctttgttgta tccacggtag caacaacatt
    32881 gccatcagca gcagatagca gccaaaatcc caaagcgcct tttcagctct ccaggggttc
    32941 atgccatcaa tttgccactt tagccaaccg ctcatcccta gcgtggcaat aaacaccagc
    33001 gccagccatc cccaaaggcg cttctgttta aaggagatca cggagaagag taaaacggat
    33061 gaaaacgcga cggtcgcagg cacgccataa acaatccaac tgagattttt tcctgcaagc
    33121 caagcgatca gcaggtagca aaccagaccc tgaagtaatc cggtagcaat catcccccaa
    33181 cgtgttgcgg gtgaaagttc aacgctatcc atgttagtta tccagaatca aaaagtgggt
    33241 taattatcgc atccgggccg tagtattttg cttttttcag aaaataatca aaaaaagtta
    33301 gcgtggtgaa tcgatacttt accgattgaa tttgcatcaa tttcattcag gaatgcgatt
    33361 ccactcacaa tattcccgcc atataaacca agatttaacc ttttaagaac attttccaca
    33421 cctaaaatgc tatttctgcg ataatagcaa ccgtttcgtg acaggaatca cggagttttt
    33481 tgtcaaatat gaatttctcc agatacgtaa atctatgagc cttgtcgcgg ttaacacccc
    33541 caaaaagact ttactattca ggcaatacat attggctaag gagcagtgaa atgcgcgtta
    33601 acaatggttt gaccccgcaa gaactcgagg cttatggtat cagtgacgta catgatatcg
    33661 tttacaaccc aagctacgac ctgctgtatc aggaagagct cgatccgagc ctgacaggtt
    33721 atgagcgcgg ggtgttaact aatctgggtg ccgttgccgt cgataccggg atcttcaccg
    33781 gtcgttcacc aaaagataag tatatcgtcc gtgacgatac cactcgcgat actttctggt
    33841 gggcagacaa aggcaaaggt aagaacgaca acaaacctct ctctccggaa acctggcagc
    33901 atcttaaagg cctggtgacc aaacagcttt ccggcaaacg tctgttcgtt gtcgacgctt
    33961 tctgtggtgc gaacccggat actcgtcttt ccgtccgttt catcaccgaa gtggcctggc
    34021 aggcgcattt tgtcaaaaac atgtttattc gcccgagcga tgaagagctg gcaggtttca
    34081 aaccagactt tatcgttatg aacggcgcga agtgcactaa cccgcagtgg aaagaacagg
    34141 gtctgaactc cgaaaacttc gtggcgttta acctgaccga gcgcatgcag ctgattggcg
    34201 gcacctggta cggcggcgaa atgaagaaag ggatgttctc aatgatgaac tacctgctgc
    34261 cgctgaaagg tatcgcttct atgcactgct ccgccaacgt tggtgagaaa ggcgatgttg
    34321 cggtgttctt cggcctttcc ggcaccggta aaaccaccct ttccaccgac ccgaaacgtc
    34381 gcctgattgg cgatgacgaa cacggctggg acgatgacgg cgtgtttaac tttgaaggcg
    34441 gctgctacgc aaaaactatc aagctgtcga aagaagcgga acctgaaatc tacaacgcta
    34501 tccgtcgtga tgcgctgctg gaaaacgtca ccgtgcgtga agatggcact atcgactttg
    34561 atgatggttc aaaaaccgag aacacccgcg tttcttatcc gatctatcac atcgaaaaca
    34621 tcgttaagcc ggtgtccaaa gcgggccacg caactaaggt tatcttcctg actgctgatg
    34681 ctttcggcgt gctgccgccg gtttctcgtc tgactgccga tcaaacccag taccacttcc
    34741 tctctggctt caccgccaaa ctggctggta cagagcgcgg catcaccgaa ccgacgccaa
    34801 ccttctccgc ctgcttcggc gcggcattcc tgtcgctgca cccaactcag tacgcagaag
    34861 tgctggtgaa acgtatgcag gcggcaggcg cgcaggcgta tctggttaac accggctgga
    34921 acggcactgg caaacgtatc tcgattaaag atacccgcgc cattatcgac gccatcctca
    34981 acggttcgct ggataacgca gaaaccttca ctttgccgat gtttaacctg gcgatcccaa
    35041 ctgaactgcc gggcgtagac acgaagattc tcgatccgcg taacacctac gcttccccgg
    35101 aacagtggca ggaaaaagct gaaacgctgg cgaaactgtt tatcgacaac ttcgataaat
    35161 acaccgacac cccagcgggt gccgcgctgg tagcggctgg tcctaagctg taatcagctg
    35221 atatctcatt gaccccttat ccaaacggat aaggggtttt tttatctaat tagctaccaa
    35281 tatgtacacg gtacacttat aattatcaat agaccgcagg atgcattatg ttcaccttta
    35341 ttgaactaca aggatttagc aaacgccgcc agttattgct acctgatgat gagttccggg
    35401 cttttcagga actactcatt caagatccca ctgccggtga cattatcgca ggcacaggca
    35461 gttttagaaa aattcgctgg aaccgttctg gaatggggaa acggggtggc attcggataa
    35521 tttattacaa cgtaacacgc aatggccgaa tttatctggc gttgatttat cctaaaaatg
    35581 aacaggatga tttaacagaa gaacaaagaa aggcattgaa actattgtcc gagaagctgc
    35641 tttaatgttg aagctccaca aattccacca tggccgaaat gtcaacggag gcattgaaaa
    35701 cagatgaaag atgaattatt tgctgatctt cttgccagcg cagaagaaat ggtacgcatc
    35761 gaaaagggtg aagaaacgcc tgaaccagag cacgtccata cttttagcga aatcgatgta
    35821 aaagcgatcc gtgaagcaac gggtttacgt cagcaagatt ttgctgtcgc cgtaggggta
    35881 agttatgacc tggtcaaaag ctgggaaacc aaacgccgtc agcctaccgg agcaccccga
    35941 aaattgctcc tgcttttgca agcgaatcct ttcattatca atcaattgaa aacaatctaa
    36001 aaacgggagg caccttcacc tcccgtttta tttacccttc ttttgtcatg ccctgcgccc
    36061 gcgttaccgg cactggcagc caggcgcgaa tggaaagccc accccgctcg ctggtgccaa
    36121 gctccaacat gccgttatgg ttatccacga tacgctgcac aatcgccagc cctaatcccg
    36181 tgccgctaat agtgcgcgca ctgtcgccgc gaacaaacgg ctggaacagg tgcttacgtt
    36241 gttccggcgc aattcccgga ccgtcatctt ccacctggaa ccaggcgcga ttcggctccg
    36301 ttccgctgct gactttgatc cagccattgc cgtaacgggc ggcgttgacc accatattcg
    36361 ccaccgcgcg tttgatcgac agcgggtgca ttttcacttc aatgctgccg gggtaaagcg
    36421 cggtttcaat ttcccgctca tagccacttt cggcggcaat cacctcaccg agcactgcgt
    36481 tgagatccgc catttccatc ggcatctcct gcccgatgcg caggtagtcg ataaactgct
    36541 caatgatggc gttgcactct tcgatatctt tattgatcga ttctgccagg tagccatcct
    36601 gctcgctcat catctcggta gccaggcgaa tgcgcgtcag cggcgtacgc agatcatgac
    36661 ttacccccgc catcagcagc gtgcgatcat ccgccagttg cttaacacca gccgccatat
    36721 ggttaaaggc gcgagtaacc gaacgcacct ccgaagcgcc atattcacgc agcggcggcg
    36781 gaataatccc tttaccgacc tgcagagcag catgttcgag atcgaccaac ggtcggttct
    36841 ggatacggat aaacagccac gccccgccta tcgccaatag cataatcgcc agcgtatagc
    36901 ggaacagcgg agaaaaatca ccctgatgaa tttcggtcag cggcacacgc acccagatat
    36961 tgggcgacag ccaggttttc agccagacaa caggagaact tttgttgacc tcaacgcgca
    37021 cttccgtcgg gccgcccagt tgctgcgcca tctgatggct taagaattca tagtgttgtg
    37081 cccaacgcag acctgcctct tcggcagctt cgttggaata gagagagatc cccagctcac
    37141 ggtagatctc ccgacggaaa gcgggaggca caaccaactg cgtgccgtcc tccagttgca
    37201 gtttgtcggt catcaacata cgcacttcgt acgcgaggac tttattaaac tgctggaggc
    37261 tcggcaaaat cgcgaagttc agcaccacca gataagtcgt caccaggctg acgaacagca
    37321 aggtgacgat gagcaataac gtacgggcaa atgaacttcg tggcgagaag cgcaatcgcc
    37381 tcatgcttta gaaccgtccg gtacaaagac gtagcccaga ccccagacgg tctgaatgta
    37441 acgcggatgc gccggatctt cttccaccat gcggcgcaga cgcgaaatct gcacgtcgat
    37501 ggagcgttcc attgcggaat attcacgacc acgggcaagg ttcatcagct tatcgcggga
    37561 gagcggctca cgcggatggc tgaccagcgc cttaagtacc gcaaactcac cactggtgag
    37621 cggcatcggc tcgtcttcgc ggaacatttc acgcgtaccg aggttaagtt tgaacttacc
    37681 gaaagcaatt accgcctctt cctgtgacgg cgcgcccggc agttcgttgg cctgacgacg
    37741 cagcaccgca cgaatgcggg ccagcaattc acgcgggtta aacggttttg gaatgtagtc
    37801 gtcagcgcca atctccaggc caacgatacg gtccacttct tcccctttcg ccgtcaccat
    37861 aatgatcggc atcgggttgc tctggctacg aagacgtcgg caaatcgaca agccatcttc
    37921 accaggtaac atcaaatcca gtaccataag atggaaagat tcacgagtca gcaggcgatc
    37981 catctgttct gcattagcga cgcttcgaac ctggaagcct tgttcggtga gataacgttc
    38041 cagcagcgcg cgcaggcgca tatcgtcatc gaccaccaga atcttgtagt tctcttgcat
    38101 tgtttgtact cccaaaggtt cgcaacaatt tgtaagcgtg tattcttaaa aaagctcacg
    38161 ttcgtcacca gctaaatctg gtatgaattt cagcctaaat tgttacaaag catattaaac
    38221 agcagcttaa gtatacaatt tattcggcga aacattattg attctgttga tatgatcacg
    38281 ttatacccaa tgtgcgcatt atcaaacaga caaagggaat caacgagatg aaaacgcccc
    38341 tggttacccg ggaagggtat gaaaaactca aacaagagct taattatctc tggcgtgaag
    38401 aacgcccgga ggtcacaaaa aaggtgacct gggccgcaag tctgggcgac cgcagcgaaa
    38461 atgctgacta tcagtataat aaaaagcgcc tgcgtgaaat cgaccgtcgc gtgcgctatc
    38521 tcactaaatg catggaaaat ctcaaaatcg tcgattactc cccgcagcag gaaggcaaag
    38581 tcttttttgg cgcgtgggtg gagattgaaa acgacgatgg cgtgactcac cgtttccgta
    38641 ttgtcggcta cgatgaaatt tttggccgta aagattacat ctctatcgat tccccgatgg
    38701 ctcgcgcatt gctgaaaaaa gaggtgggcg atttggcggt ggtgaatacc cctgccgggg
    38761 aagcgagctg gtatgttaat gctatcgagt acgtgaaacc gtaaggaaga gtcttaacct
    38821 cctgccgatg gctggcattt ttgccagcca gtccgtataa ctatcccctg atttttgatc
    38881 cgaaaagatg aactcaaacc atgatgaatg attcgttctg ccgcattatt gcgggtgaaa
    38941 ttcaggcgcg cccggaacag gttgacgctg ccgttcgcct gcttgacgaa gggaataccg
    39001 tgccgtttat cgcacgttat cgtaaggaaa tcaccggcgg tctggatgac acgcagctgc
    39061 gtaatctgga aacgcgtctg agctatctgc gcgagctgga agagagacgt caggcgatcc
    39121 tcaagtccat ttccgagcaa ggcaaactca ccgatgatct ggcgaatgcc atcaacgcca
    39181 ccctaagcaa aaccgaactc gaagacctct acctgcccta caaacctaaa cgccgcaccc
    39241 gtgggcaaat cgccattgaa gcagggcttg agccgttggc cgatctgctg tggagcgatc
    39301 cgtcacacac gccagaagtc gccgctgcac aatatattga tgccgataaa ggcgtggcag
    39361 ataccaaagc cgcgctggac ggcgcgcgct atatcctgat ggaacggttt gccgaagatg
    39421 ccgcgctgct ggcgaaagtg cgtgattatc tgtggaagaa cgcgcatttg gtctcaaccg
    39481 tggtgaatgg taaagaagag gaaggggcga aattccgcga ctatttcaat catcacgaac
    39541 cgctgtccac ggtgccttct caccgcgcgc tggcgatgtt ccgtggtcgt aacgaaggca
    39601 tacttcagct ttcgctgaat gccgatccgc agttcgaaga gccgccaaaa gagagctatt
    39661 gcgagcaaat catcatggat caccttggcc tgcgcctgaa caatgccccg gcggatagct
    39721 ggcgcaaagg tgtggtgagc tggacgtggc gcatcaaggt gttgatgcat ctggaaactg
    39781 aactgatggg caccgtgcgc gaacgcgcgg aagatgaagc aatcaacgtc tttgcccgta
    39841 acctgcacga tctgctgatg gcggccccag ccggactgcg tgcaacgatg ggcctcgatc
    39901 cgggtctgcg taccggggta aaagtagcgg tggtcgatgc aactggcaaa ctggtggcga
    39961 ccgataccat ttatccacat accggacaag ccgcaaaagc agcgatgacc gttgctgccc
    40021 tgtgtgaaaa gcataacgtt gaactggtgg cgatcggcaa cggtacagct tcccgcgaaa
    40081 ccgagcgttt ctatctcgac gtgcagaagc agttcccgaa agtgaccgcg cagaaagtga
    40141 tcgtcagcga agctggcgcg tcggtttact cggcttccga gctggcagca caggagttcc
    40201 cggatctcga cgtttcgctg cgtggcgcgg tgtctatcgc ccgccgtttg caggatccgc
    40261 tggcggagct ggtgaaaatc gatccgaaat ctatcggcgt aggtcagtat cagcatgacg
    40321 tcagccagac gcaactggcc cgcaaactgg acgcagtagt agaagactgc gtaaacgccg
    40381 ttggcgtcga tctcaacacc gcttctgttc cgctgttaac tcgcgtggcg ggcctgacgc
    40441 gcatgatggc gcaaaacatc gttgcctggc gcgatgagaa cggtcagttc cagaaccgtc
    40501 agcaactgct gaaagtgagc cgtctggggc cgaaagcctt cgagcagtgc gcgggcttct
    40561 tgcgcattaa ccatggtgat aacccgctgg acgcgtctac cgtccacccg gaagcctatc
    40621 cggtggtgga acgcattctg gcagcaacac agcaggcact gaaagatctg atgggtaaca
    40681 gcagcgagtt gcgtaacctg aaagcgtctg actttactga tgaaaaattc ggtgtaccga
    40741 cggtaactga catcatcaaa gagctggaaa aaccgggtcg cgatccgcgt ccggaattta
    40801 aaaccgctca gtttgccgat ggcgtcgaaa cgatgaacga cctgcaaccg ggtatgatcc
    40861 tcgaaggtgc ggtgaccaac gtcaccaact ttggcgcgtt tgtcgatatt ggcgtgcatc
    40921 aggacggcct ggttcacatc tcttcattgt cgaacaagtt tgtggaagat ccgcataccg
    40981 tggtgaaagc gggcgatatt gtgaaggtga aagtgctgga agtggatctt cagcgcaaac
    41041 gtatctccct gactatgcgt ctggacgagc agcctggcga aaccaacgct cgtcgcggcg
    41101 gcggtaatga acgtccgcag aacaaccgcc cggcagccaa accgcgtggg cgtgaagcgc
    41161 agcctgccgg taatagcgcg atgatggatg cgctggcggc ggcaatgggc aaaaaacgtt
    41221 aaacgcccgg actggcccct aaacctgcgc gattaggcgt tcacgccaca tctggcaacg
    41281 aacgccttgc ctgacataaa agtgccggag aatatctccg gcctttttat tccacaagca
    41341 aactcataat atatcccgtt aatatttatc acttcattaa caactgaaac cttaattaaa
    41401 cattaaccag ccctaataat tcgtcatgcg aattatattt tcgctgcgat ataaccttga
    41461 gccatatcaa cattgagtca gattattatt caaaccaaca ttcacacaca ttttaagtat
    41521 tgctgataga aaccattctc attatcattg tactgttgat tatttaatct ctccttcgtt
    41581 ggcaaatcat ctggtctcat gtcgctgtca aacgccccat gaggtagtta tccagttaat
    41641 gagaaacaag taggcaccta tgcaatacac tccagatact gcgtggaaaa ttactggctt
    41701 ttcccgtgaa atcagcccgg catatcgcca aaaactgctt tctcttggca tgttacctgg
    41761 ctcctctttt aatgtggtgc gcgtcgctcc actcggcgac cccattcata tcgaaacccg
    41821 tcgtgtgagc ctggtattac gcaaaaaaga tctggcctta ttagaagtgg aagcggtttc
    41881 ctgttaatac ggtgataaca acaatgaaaa aattaaccat tggcttaatt ggtaatccaa
    41941 attctggcaa gacaacctta tttaaccagc tcactggcgc acgtcagcgt gtaggtaact
    42001 gggctggcgt taccgtcgaa cgtaaagaag ggcaattctc caccaccgat catcaggtca
    42061 ccctggtgga cctgcctggc acctattctc tgaccaccat ctcatcgcag acctcgctcg
    42121 atgagcaaat cgcctgtcac tatattctga gtggcgacgc cgacctgctg attaacgtgg
    42181 tggatgcgtc taaccttgag cgtaacctgt acctgacgct gcaactgctg gaactcggca
    42241 ttccctgcat cgtggcactg aacatgctcg acattgccga gaagcaaaat attcgcattg
    42301 aaattgatgc tctgtcggcg cgtcttggct gcccggtgat cccgctggtt tcaacccgtg
    42361 gtcgcggtat tgaagcgctc aagctggcga ttgatcgcta taaagctaac gaaaatgtgg
    42421 aactggtgca ttacgctcag ccgctgctca acgaagcaga ttcactggca aaagtgatgc
    42481 cttccgacat cccgctgaaa caacgtcgct ggctgggcct gcaaatgctg gaaggcgata
    42541 tctacagccg cgcctacgcc ggtgaagcgt cgcagcatct ggatgccgcc ctcgcccgtc
    42601 tgtgtaatga gatggacgat ccggcgctgc acattgccga tgcgcgttac cagtgcattg
    42661 ctgccatctg tgatgtggta agcaacaccc tgacggcaga acccagccgt ttcaccactg
    42721 cggtagataa aatcgtgctc aaccgtttcc tcggtctgcc gattttcctc tttgtgatgt
    42781 acctgatgtt cttgctggct atcaacatcg gcggggcgtt acagccgctg tttgacgtcg
    42841 gctccgtggc gctgtttgtg catggtattc agtggattgg ctacacgctc cacttcccgg
    42901 actggctgac tatcttcctc gcccagggcc tgggtggcgg tattaacacc gtgctgccac
    42961 tggtgccgca gatcggcatg atgtacctgt tcctctcctt cctcgaggac tccggatata
    43021 tggcgcgtgc ggcgtttgtg atggaccgtc tgatgcaggc gctgggcttg ccggggaaat
    43081 cctttgtacc gctgatcgtt ggtttcggtt gtaacgtacc gtcggtaatg ggcgcacgta
    43141 cgcttgatgc accgcgtgaa cgtctgatga ccatcatgat ggcaccgttt atgtcctgcg
    43201 gcgcgcgtct ggctatcttc gccgtattcg cggctgcttt cttcgggcag aacggtgcgc
    43261 tggcggtctt ctcgctgtat atgctgggta tcgtgatggc ggtgctaact ggcctgatgc
    43321 tcaagtacac catcatgcgc ggtgaagcga cgccgtttgt catggagctg ccggtctacc
    43381 atgtaccaca cgttaaaagc ctgattatcc agacctggca gcgtctgaaa ggcttcgttc
    43441 tgcgtgctgg taaagtgatc atcatcgtca gcattttcct gagcgctttc aacagcttct
    43501 cgctgagcgg gaaaatcgtc gataacatca acgactcggc gctggcgtcc gtcagccggg
    43561 tgatcacccc ggtcttcaag ccaattggtg tgcatgaaga taactggcag gcaacggttg
    43621 gcctgtttac aggtgccatg gcgaaagaag tggtagtggg tacgctcaac accctctaca
    43681 ccgcagaaaa tattcaggac gaagagttca atccggcaga gtttaacctc ggtgaagagc
    43741 tgttcagtgc ggtagatgaa acctggcaga gcctgaaaga caccttcagc cttagcgtac
    43801 tgatgaaccc cattgaagcc agcaaaggcg acggcgaaat gggtaccggg gcgatgggcg
    43861 tgatggatca gaaattcggt agcgcagcag cagcttacag ctacctgatt ttcgtcctgc
    43921 tgtatgtacc atgtatctcg gtgatgggag ccatcgcccg tgaatcaagc cgtggctgga
    43981 tgggcttctc catcctgtgg gggctgaata tcgcttactc gctggcaaca ttgttctatc
    44041 aggtcgccag ctacagtcag cacccaactt acagcctggt gtgcattctg gcggttatcc
    44101 tgtttaacat tgtggttatc ggtttgctgc gtcgcgcgcg tagccgggtg gatatcgaac
    44161 tgctggcaac ccgcaagtcg gtaagcagtt gctgcgcagc cagcaccacc ggtgattgcc
    44221 attaatggct tcacttattc aggtgcgtga tttgctggcg ttacggggcc gtatggaagc
    44281 ggcccagata agccagacat tgaacactcc gcagccaatg attaacgcca tgctgcaaca
    44341 gctggaaagc atgggcaaag ccgtgcggat tcaggaagaa cctgacggct gcctctctgg
    44401 cagttgtaaa agctgcccgg aaggcaaagc ctgtctgcgc gagtggtggg cgctgcgtta
    44461 accatactcc atcgcctgtt ttgaaaagcc cggtatgcgt ttgcatccgg gcttttttgc
    44521 gtgcggcttt ccataaaaat gcaattcttg cagcgcgacg taagttcctc tgaaagcgtc
    44581 tcgcagggat gaaaactggc taatgcacag gtgtggagtg gcgcgtagag tcgcggcatt
    44641 caaacaacag gtgaaggaac gccatgagca aaaagcagag ttccacccca cacgatgcgc
    44701 tgttcaaact ctttttacgc caaccggaga cggcacgcga ttttcttgcg tttcatttac
    44761 cggcacccat tcacgcgctc tgtgatatga aaaccctcaa gctggagtcg agcagcttta
    44821 ttgatgacga tctgcgtgaa agctattccg atgtgctgtg gtcggtgaaa acggaacaag
    44881 gaccaggata catctattgt ctgattgaac atcaaagcac ctcaaacaaa ctgatcgcat
    44941 ttcgcatgat gcgttacgct attgccgcaa tgcaaaatca cctggatgcc ggatacaaaa
    45001 ccttgccgat ggtggtgcca ttgttgtttt accacggtat tgaaagcccc tatccctatt
    45061 cgctgtgttg gctggattgt ttcgccgatc ccaacctggc aaggcagctt tatgcctccg
    45121 catttccgct gattgatgtc accgtcatgc ctgatgatga aatcatgcag caccgacgta
    45181 tggcgctgct ggagttaatt caaaaacata ttcgtcaacg cgatctgatg ggactggtag
    45241 agcaaatggc ctgcttatta agtagtggat acgctaatga cagacaaatc aaagggctgt
    45301 ttaattacat actgcaaact ggcgatgcgg tacgttttaa cgattttatc gacggtgtgg
    45361 ccgaacgttc accgaaacac aaggagagct taatgactat tgcggaaaga ttgcggcaag
    45421 agggggaaca atccaaagcc ttgcatatag caaaaataat gcttgaatcc ggagtccctc
    45481 ttgcggacat catgcgtttt accggggtgt cagaagaaga gttggctgcg gcgagtcagt
    45541 aaagttctgt ctcgccattt caaaagccac ctacaccctc tgcttcaacg ccaccagcat
    45601 gcgacaaaac tcggccggat gcgaaataaa cggcgcatgg gccgctttgg cgaagatgta
    45661 tgattcgctg tgaggccaaa gtttatccag catcggcacc actttgcgcg gcaccagacc
    45721 gtcgagatag ccatacaatc gcaaaaacgg catggacacg ttttgcagcg gctgacggag
    45781 atcgaccgtt ttcaggattt ccagcccgcc attaagcacg tcaacctccg gcatcggtaa
    45841 cgccagaacg gttttcttca acgcccgcgc atcctggcgc gccgtttcag tacccatggt
    45901 ttgtaacgcc aggaaccgct ccactgtacg ctgaaaatca tcactgagtt gctgctgaaa
    45961 tcccgccagc acgtccggtt ttatccccgg ccactcgtca cgagcactaa aacaaggtga
    46021 cgacgccacg gtgaccagcg cctgaacacg ctcgggatgg gttaacgcaa tctggcttgc
    46081 caccagcccg cccagactcc agcctaacca aatggcttta tcaggtgcct gtcgcagcac
    46141 ggcttcggcc atatcagcaa gtgacatcgc accaaatccc cggctacgcc cgaagccggg
    46201 caggtcaaca aggtgcagcg taaaatgcga gctcagttcc tcgtcaatgc aacgccacac
    46261 ttcggcattc agtccccatc cgtgcagcag cacaagatga acattcccct gacctttggt
    46321 ctgccaccag atgttattca tccgttattg ttctcttttg acttacaagg atgaacatat
    46381 gctaacagta ccgggattat gctggctatg ccgaatgccg ctggcgttag gtcattgggg
    46441 gatttgttcg gtctgctcac gcgccgcccg taccgataaa acgttatgcc cacaatgtgg
    46501 attacccgct acacacgccc atcttccctg cggccgctgc ctgcaaaaac caccgccctg
    46561 gcaaagactg gtcacggttg ccgactatgc gccgccgtta agtccgctca tccaccagct
    46621 taagttttcc cggcgttgcg aaatcgccag cgccctgtca cgtctgttac tattggaagt
    46681 cttacacgct cgtcgcgcca ccggtttgca attgccggat cgcattatca gcgttccgtt
    46741 atggcagcgg cgtcactggc gtcggggatt tagtcagagc gatttgctgt gtcagccgtt
    46801 atcacgctgg ttgcactgcc gatgggatag cgaagccgtt acacgaacac gggccgctgc
    46861 gacccagcat tttctcagtg cccggctgcg caagcgcaac ctgaaaaatg cctttcgcct
    46921 tgaattgcct gtgcaaggtc gccatatggt gattgtggat gatgtcgtta ccaccggaag
    46981 taccgtcgca gagattgcgc agttgctttt acgcaatggt gcggcgactg tccaggtctg
    47041 gtgcctttgt cgaaccttgt agagcctcga tgatgggcgt attataacca actaaaatag
    47101 tcaactatta ggccattact atgatccgta tttccgatgc tgcacaagcg cactttgcca
    47161 aactgctggc aaatcaggaa gaagggacac aaatccgcgt atttgtgatt aaccctggca
    47221 cgcctaacgc tgaatgtggc gtttcttatt gtccgccgga tgctgtggaa gccaccgaca
    47281 ctgccctgaa atttgacctg ctgaccgcgt atgttgatga gttaagcgct ccttacctgg
    47341 aagatgcaga gatcgatttt gttaccgacc agttgggttc tcagctaaca ctgaaagcac
    47401 ctaacgcaaa aatgcgtaaa gtggcagacg atgcaccgct gatggagcgc gtggagtata
    47461 tgctacagtc gcagatcaac ccacagcttg ctggtcacgg tggtcgcgtg tcgctgatgg
    47521 aaatcaccga agacggttac gccattctgc aatttggcgg cggctgtaac ggttgttcca
    47581 tggtcgatgt gacgctgaaa gaagggatcg agaagcagct gctaaacgaa ttcccggagc
    47641 tgaaaggcgt gcgcgatctc accgaacacc agcgcggcga acactcctac tactaagtta
    47701 tcccctcttt tgtagattgc ccgatgcgac gctaaagcgt catttcgggc ctacgttgaa
    47761 catgtgccag acgttggcgc tgcattgctt tggcaaatcc ctcccttcgt ttccccgcga
    47821 taatatgacc aacctctcat aatttaaatt taccccgctc tggtgattct caaacgccag
    47881 atgttacccg tatcattcac atgggtacca aacatactcc tgacatctga ctacaataat
    47941 tagttttagt gggtatcagt cgtggtgccg caatatctct gttcccgatt gggataatta
    48001 gagtttgtcg tcagaaaatt gacgttaccc ataacaaatg aaaggccagg taaatcatgc
    48061 cattagtcat tgttgctatc ggtgtaatct tgttgttgct cctgatgatc cgcttcaaaa
    48121 tgaacggctt catcgctctc gtcctcgtgg cgcttgctgt tggattaatg caagggatgc
    48181 cgctggataa agttattggc tccatcaaag ccggtgtcgg cggaacgctc ggtagccttg
    48241 ccctgatcat gggttttggc gcaatgctgg gcaaaatgct ggcagactgc ggtggcgcac
    48301 aacgtatcgc caccacgctg attgctaaat ttggtaaaaa acacatccag tgggcggtgg
    48361 tactgaccgg ttttaccgtt ggttttgccc tgttctatga agtgggtttc gtgctgatgc
    48421 tgccgctggt gtttaccatc gcggcttccg cgaatattcc actgctgtat gttggtgtac
    48481 caatggcggc tgcactgtct gtgacccacg gcttcctgcc accgcatccg ggtccgactg
    48541 cgattgccac cattttcaat gccgatatgg gtaaaactct gctgtatggg actattctgg
    48601 caattccgac cgtgattctc gccggtccgg tttacgctcg cgtgttgaaa ggtatcgata
    48661 agccgatccc ggaaggtctg tacagcgcga aaaccttcag cgaagaagag atgccgagct
    48721 ttggcgtcag cgtctggacc tctctggtgc cggtagtgct gatggcgatg cgtgcgattg
    48781 ccgaaatgat cctgccgaaa ggtcacgctt tcctgccggt agcggagttc ctcggtgacc
    48841 cggtaatggc tacgctgatt gccgtactga ttgcgatgtt cacctttggt ctgaaccgtg
    48901 gtcgttcaat ggatcaaatt aacgacacgc tggtttcttc catcaaaatc attgcgatga
    48961 tgctgttgat tatcggtggt ggcggtgcgt tcaagcaggt gctggtagac agcggcgtgg
    49021 ataaatacat tgcttccatg atgcacgaaa ccaacatttc tccgctgctg atggcctggt
    49081 cgattgctgc cgtactgcgt atcgcgctgg gttccgcaac cgttgcggca atcactgcgg
    49141 gtggtatcgc ggcaccgctg attgcaacga cgggtgttag cccggagctg atggttattg
    49201 cggttggttc cggtagtgtg attttctctc acgtgaacga tccgggcttc tggttgttca
    49261 aagagtactt taacctgact atcggcgaga ccatcaaatc ctggtcgatg ctggaaacca
    49321 ttatctcggt gtgcggtctg gtaggctgtc tgctgctgaa tatggtgatt tgataacact
    49381 gactgccgga tgcatcgcat ccggcatcaa ccgcacccta ctacttcttc gctgccgctc
    49441 tgcgccgtct gtccaaatcc ttcagcaact tgttcacgcc atcatcggca aacatcgcct
    49501 caagcgttgc ggagagcttg cgccgccagt ttttatactg gtaactggtg ccgggaatat
    49561 ttaccggatc cgccatatcc agccagtctt ctggctgtag tcctaacagg gcgctgttgc
    49621 tatcggcgat gtagcgctgt aagccacgat tcagcgtcgg cgtcatcgac atcaacgatg
    49681 ccttatgccc ggcacgtttt ggcagacaac catatttatg cagagcatcc agtagtcctt
    49741 gcttcgccag ttcgcgatcc tgatacagac cgcgcagtac cacttcatcc ggatacaacc
    49801 ccagcgtttt gcccagcgtt agatccccgc tctcccagta gccgcgtagc gtaggcaggt
    49861 cgtgtgtcgc cgcaaccgcc atcgactgct ctgggtacgc tttcggcgcg cggaatgtct
    49921 tctcgtggtc gttttcgaaa tagagcactt tgtaggagta cacaccgctg ctgcgcagct
    49981 taccgacaat ctctaccggt acggtaccga gatcttcacc aatcaccata cagcgatgac
    50041 gcttactttc gagtgccaga atcgagagca gatcatccac cggatagtga acatatgccc
    50101 cctgatctgc cgtctcgcca tacggtatcc accacaaacg cagcatcgac atcacatggt
    50161 caattcgtaa tgcgccgcag ttttgcatat tggcacgcaa cagctcgata aacggttcat
    50221 aggcacgcgc ggtgatgata tgcgggtcca ttggcggcaa tccccagttc tgccccaacg
    50281 ggccgaggat atccggcggc gcgccaaccg acgctttcag gcaatacagt tcacggtcgc
    50341 accaggtttc tgccccacct tctgctacac caacggccag atcacgatac aagccaatcg
    50401 gcatttcata gtcctggctt atctcccagc aggcggcaaa ctggctgtaa gccagccact
    50461 gcaaccagag ataaaaatcg acgtcatcac gatgttcttc gcagaactgg cgcacttctg
    50521 gtgaatccac gttctgatac atctctggcc atgcaggcca gccccagcgc atttcgtcct
    50581 ctttcacttg ctgggcatgt agtgcgtcaa acgccgcctg ccagaacagg ctgtcgcctt
    50641 gctctgcaac aaactggcga aacgcggcca tctgttcatc atcacgttgc gcgaaacctt
    50701 tccacgccat tcgtaatgct gtcattttta gggcggtaac cgtggagtaa tcgacccagt
    50761 cggcatcccg cgcctgttgc agcgtctgtt gcatggtcgg caacttccac caggcctgag
    50821 cctcttcgct aagatggaaa tcttcaacgg cgttaacgtc gatataaatc acattcagcc
    50881 aacggcgaga agacgggcta tacgggctgg cactttccgg atttgccgga tagagcgcat
    50941 gaatcgggtt cagaccgatg aacgacccgc cacgttttgc cacatccacc agcatcgctt
    51001 tgagatcgcc aaaatcccca ataccccagt ttttttccga tcgcagtgta taaagctgaa
    51061 cgcaggcacc ccacagcttt tgtttgttca gcaacgcctg cggttcgtaa cagcgtttcg
    51121 gggcgacaat cacccggcaa tgcgcgcgct ggtcgtcctg ggtgactgtc agcgtgtgat
    51181 aaccttccgg cagcttcgtc ggtagattga acgctttgcc ccccgttaca tggcctttgt
    51241 actgcgttcc ttcttcggtg gtcagcagcc agctatattc gccgctgccc tccaccgcca
    51301 tcggcatttt tttgccgctg gtatagacca tgacattcgg gactggcgtt accgccactt
    51361 tcgtggcggt acgttgatgc atcgcgtcaa gcaaacgccg tttggtttcg gcgctaatcg
    51421 actgcggttt accgtgggca ttgatgtaat tggggctgat ccccgccgcc agcgcggcat
    51481 tatccagacg tttgctttcc atcgagcttc cttagcgttt tgcctgccag atacgagcct
    51541 gataatcgcg aatagagcga tccgagctaa acataccgca gcgggcggta ttgaggatcg
    51601 ccgcgcgagt ccaggcctcc tggtcgcggt acagcacatc cacctgcttt tgtgcctcta
    51661 cataagcggc gaaatccgcc atcaccagat acggatcgcc gccctgtttg ccgatactgt
    51721 gcagcatctg atcgaaggca tgcttatcgc cgtcgctgta tttaccgctt tccagctctt
    51781 tcaatactgc gtccagcacc ttatctttct tccgccattt caccgggtcg tagcctttgg
    51841 ccagaattgc cttcacttgt tccacggtat gaccaaaaat aaagatattt tcttcaccaa
    51901 ctttctcagc gatttcaacg ttcgcaccat ccagcgtacc gacagtaagc gcaccattga
    51961 gcgccagttt catattgccg gtaccggaag cttctttacc tgccgtcgaa atttgttcgg
    52021 agatatccgc cgccgggatc agtttttccg ccgccgaaac acaataatcc ggcaggaaca
    52081 ccaccttcaa tttgtcgcca acctgcggat cgttgttgat cacgtcagcc actttgttga
    52141 tcgcaaagat aatgttcttc gccaggtagt agcccggtgc cgctttcgcg ccaaagagga
    52201 agacgcgcgg tacgcgatca gcctgcgggt tttcacgaat ttctttgtac aacgccagaa
    52261 tatgcagcag attcaggtgc tggcgtttgt actcatgcag acgtttgatc tgaatatcga
    52321 aaatcgcctg tggattgatc tcaataccgg tacgaacttt cacaaactct gccagacgga
    52381 ctttattcgc ctgcttgatc tcgcgatatt gctgacggaa tttcgcatca tcagcgaatt
    52441 tttccagatt gatcagttga tcgagatcgt tagcccactc ttttttcagt gatttatcca
    52501 acagagccgc cagtgccggg ttgcactgtt tgatccagcg acgtggggta ataccgttgg
    52561 tgacgttatg gaatttgttc ggccatagct ggtgatattc cgggaacaga tctttcacca
    52621 ccagatccga gtgcagcgcc gcaacaccgt ttaccgcgaa accgccaacc acacacaggt
    52681 tcgccatatg cacttgtttg tcgtgcacca ccgccagttt ggcccacact ttttcatcgc
    52741 ccggccaggt tttctccacc agcgttttaa agcgtgtatt aatttcgtta ataatctgca
    52801 tgtggcgcgg cagtaagcct ttcaccagtt tcacatccca gcgttccagc gcttctggca
    52861 tcagggtatg gttggtgtaa gcgaaagttt tactggtgat agcccaggcg tcatcccagc
    52921 tcatctggtg ctcatcgatc agcacgcgca gcagttctgg aatcgcgata gttgggtggg
    52981 tatcgttcag ctgaataact tcgtaatccg ccagttcgtg caatttacgc cccgccagat
    53041 gatggcgacg caaaatatcc gctaccgaac aggcacactg gaagtattgc tgcatcaggc
    53101 gcagcttttt accggcagta tggttgtcgt ttggatagag aactttggtc agtttttccg
    53161 cgttgatgcc ctgctgttcg gcacgcagga aatcaccatc gttaaattta gtcagatcaa
    53221 acggatgcgc atgcgtcgcc tgccacagac gcagtggctg cgccacgcca ttacgatagc
    53281 cgacaacggg gagatcccac gcttgaccag taatggtaaa ttccggctcc cagcgtccgt
    53341 ctttcgtcac tttaccgcca atccctacct gcacatccag tgcttcattg tggcggaacc
    53401 acggatagtt accacgatgc cagtcatccg gcgcttcaac ctgtttgcca tcgacaaatg
    53461 actggcggaa caagccatat tgataattaa ggccgtagcc agtagctgac tgcccgacag
    53521 ttgccattga gtcgaggaag cacgccgcca gacgtcccag accaccgtta cccagcgccg
    53581 ggtcgatctc ttcttccagc aagtcagtca ggttgatgtc ataagccttc aacgaatcct
    53641 gtacatcctg ataccagccg agattcaaca gattgttgcc cgtcaggcga ccaatcaaaa
    53701 actccattga gatgtagtta acatgccgct gattcgccac cggtttggca aattgctgag
    53761 cacgcagcat ttcggccagt gcttcgctca ctgccagcca ccactgacga ggggtcattt
    53821 cagccgcaga atttaagcca taacgctgcc actgacgtga aagcgcttcc tgaaattgct
    53881 tatcgttaaa aataggttgt gacataggag ttccactttt cttagatttt caacacaacg
    53941 ttatcgctag tttgccaggc tcgatgttga ccttcctcat cctgcggggg attaggcagg
    54001 gaggagttgc ggggatgagc aaggaaatgt gatctcgacc acttaaagct agtgcaaacc
    54061 acaggattag cagcaaatca atgccataca gcgcagaaaa tctgtatcta agtgcaaaaa
    54121 atggccgttg cgtattttca aaaagcggaa ggtaactcta taaattaagt aaaggagtga
    54181 aacagtttca taagtaaaat atcaagtgtg ctccatctca ttcttaatag atttattaag
    54241 atcatctttt tagatggcac tttcatcagg gataaagaag aaacccttgc ttaaatgaaa
    54301 ctgatgaaca taaggaaaat accgtacaac ccagtattca cgctggatca gcgtcgtttt
    54361 aggtgagtca ttaataaaga tttggaattg tgacagagtg caaattcaga cacataaaaa
    54421 aacgtcatcg cttgcattag aaaggtttct ggccgacctt ataaccatta attacgaagc
    54481 gcaaaaaaaa taatatttcc tcatattcca cagtgaagtg attaactatg ctgattccgt
    54541 caaaattaag tcgtccggtt cgactcgacc ataccgtggt tcgtgagcgc ctgctggcta
    54601 aactttccgg cgcgaacaac ttccggctgg cgctgatcac aagtcctgcg ggctacggaa
    54661 agaccacgct catttcccag tgggcggcag gcaaaaacga tatcggctgg tactcgctgg
    54721 atgaaggtga taaccagcaa gagcgtttcg ccagctatct cattgccgcc gtgcagcagg
    54781 caaccaacgg tcactgtgcg atatgtgaga caatggcgca aaaacggcaa tatgccagcc
    54841 tgacgtcact cttcgcccag cttttcattg agctggcgga atggcatagc ccactttatc
    54901 tggtcatcga tgactatcat ctgatcacta atccagtgat ccacgagtca atgcgcttct
    54961 ttattcgcca tcaaccagaa aatctcaccc tggtggtgtt gtcacgcaac cttccgcaac
    55021 tgggcattgc caatctgcgt gttcgtgacc aactgctgga aattggcagt cagcaactgg
    55081 catttaccca tcaggaagcg aagcagtttt ttgattgccg tctgtcatcg ccgattgaag
    55141 ccgcagaaag cagtcggatt tgtgatgacg tttccggttg ggcgacggca ctgcagctaa
    55201 tcgccctctc cgcccggcag aatacccact cagcccataa gtcggcacgc cgcctggcgg
    55261 gaatcaatgc cagccatctt tcggattatc tggtcgatga ggttttggat aacgtcgatc
    55321 tcgcaacgcg ccattttctg ttgaaaagcg ccattttgcg ctcaatgaac gatgcactca
    55381 tcaaccgtgt gaccggcgaa gaaaacgggc aaatgcgcct cgaagagatt gagcgtcagg
    55441 ggctgttttt acagcggatg gatgataccg gcgagtggtt ttgctatcac ccactgtttg
    55501 gtaacttcct gcgccagcgc tgccagtggg aactggcggc ggagctgccg gaaatccacc
    55561 gtgccgccgc agaaagctgg atggcccagg gattccccag cgaagcgatt catcatgcgc
    55621 tggcggcagg cgatgcgctg atgctgcgcg atattctgct taatcacgcg tggagtctgt
    55681 tcaaccatag cgaactgtcg ctgctggaag agtcgcttaa ggccctgccg tgggacagtt
    55741 tgctggaaaa tccgcagttg gtgttattgc aggcgtggct gatgcaaagc cagcatcgct
    55801 acggcgaagt taacaccctg ctggcccgcg ctgaacatga aatcaaggac atcagagaag
    55861 gcaccatgca cgcagaattt aacgctctgc gcgcccaggt ggctattaac gatggtaacc
    55921 cggatgaagc ggaacggctg gcaaaactgg cactggaaga actgcctccg ggctggttct
    55981 atagccgcat tgtggcaacc tcggtgctgg gtgaagtgtt gcactgcaaa ggcgaattga
    56041 cccgctcact ggcgttaatg cagcaaaccg aacagatggc acgccagcac gatgtctggc
    56101 actacgcctt atggagttta atccagcaaa gtgaaattct gtttgctcag ggattcctgc
    56161 aaaccgcgtg ggaaacgcag gaaaaagcgt tccagctgat caacgagcag catctggaac
    56221 agctgccaat gcatgagttt ctggtgcgca ttcgtgcgca gctgttatgg gcctgggcgc
    56281 ggctggatga agccgaagcg tcggcgcgta gcgggattga agtcttgtcg tcttatcagc
    56341 cacagcaaca gcttcagtgc ctggcaatgt tgattcaatg ctcgctggcc cgtggtgatt
    56401 tagataacgc ccgtagccag ctgaaccgtc tggaaaacct gctgggaaat ggcaaatatc
    56461 acagcgactg gatctctaac gccaacaaag tccgggtgat ttactggcaa atgaccggcg
    56521 ataaagccgc cgctgccaac tggttgcgtc atacggctaa accggagttt gcgaacaacc
    56581 acttcctgca aggtcaatgg cgcaacattg cccgcgcaca aatcttgctg ggcgagtttg
    56641 aacctgcgga aattgttctc gaagaactca atgaaaatgc ccgcagtctg cggttgatga
    56701 gcgatctcaa ccgtaacctg ttgctgctta atcaactgta ctggcaggcc ggacgtaaaa
    56761 gtgacgccca gcgtgtgttg ctggacgcat taaaactggc gaatcgcacc ggatttatca
    56821 gtcattttgt catcgaaggc gaagcgatgg cgcaacaact gcgccagttg attcagctta
    56881 atacgctgcc ggaactggaa cagcatcgtg cgcagcgtat tctgcgagaa atcaatcaac
    56941 atcatcggca taaattcgcc catttcgatg agaatttcgt tgaacgtctg ctaaatcatc
    57001 cggaagtgcc agaactgatc cgcaccagcc cgctgaccca acgtgaatgg caggtcctgg
    57061 ggctgattta ctccggttac agcaacgagc aaattgcagg cgagctggaa gtggcggcaa
    57121 ccaccatcaa aacgcatatc cgcaatctgt accaaaaact cggtgtcgcc caccgtcagg
    57181 ccgcggtaca acacgcgcag aaactgctga agatgatggg atatggggtg tgagtttagc
    57241 cggataatac gtcggatccg gcttacatct ttatatcatt caatgctcac ccgcgttacg
    57301 ccatcagcct ccaccagacc aaaccgcact ggcaagaaac gctccaccac cgcgatattg
    57361 gtcagcagat ggcatgaggg atgggcgacc gtaaattctc ccgcgcccgc cagcgccatc
    57421 ggtagcacca actggtcggc gagatattcc cccaccgccg ccgggcttgc caggtagcgt
    57481 ttcacctctt tcaccaactg cgcggcgacc acctcggcgc tgacgcgctt ttcaccgacg
    57541 ataaaaaagc gttcggtgat attttcactt tcgacttcaa gcgagacggt attacccggt
    57601 ccctggtcac gcggcaggtt atgaatattc ttctcatgca gggaaaaact acccaccagc
    57661 gtagcgattt cacgctcagc gacatgcctc ggcacgccag ctaacagcac ctctccacgc
    57721 atctgcacaa tgttcccgcg ctcgccaagt tgcaaagtgt taaacgatgc cacgggcgag
    57781 acttccgtcg ccaccacccc gcctccggca ggataaaaac cgtggcgtaa taatgtggtt
    57841 tgctgatgaa tgcccatttt cgccagcagc ggctccagca cccggcggat aaaatccgca
    57901 ggcggtgccg acgggttatc ggtgccgccg ctcacttcaa cacgcgaagg cccgtcagca
    57961 aaccacagcg cgggcagcac cgtttgcagc accagcgtgc tgcttccggc gctaccgata
    58021 gcaaagcggt aatcgccgcc gcgcacggtg ccaggccgga agaccagacg ctgcgacccc
    58081 agctccgcgc cttccaccgt tgctcggcaa atttccgtcg ccgccttaac cgcggtcaga
    58141 tgctggcgca acagccccgg tttcgcccgc ccggcacgaa tgccagtgat ggtaaatggc
    58201 tggccagtta tcatcgacag gctcagcgcc gagcgcagga tctgcccgcc gccttcgccc
    58261 tgtgcgccat ccagcgcaat catccttttc atcatttatc cttttacaca caccacctga
    58321 cgcagggtgt agataacttc caccagatcg ctttgtgccg ccatcaccgc gtcgatatct
    58381 ttatacgcca tcgggatttc gtcgatcact tcggcatctt tacggcattc cacatgcgcg
    58441 gtggcacgaa tttgatcttc cacgctgaac agttttttcg ctttagtacg gctcattacc
    58501 cgcccggcac cgtggctgca cgaacagaac gactctacat ttcccagccc acggacgata
    58561 aagcttttcg ctcccatcga ccctggaata attccatatt gaccagcacg cgcagacacc
    58621 gcgcctttac gcgtcacgta gatctcttca ccaaagtgct gttctttttg cacatagttg
    58681 tggtgacagt tgatctcttc catcgccagc gtttgcggct gccttaccgt tttctgcgta
    58741 atgctctgca acgccgttac cacgttttcc atcatcgcat cgcggttaag gctggcaaaa
    58801 agctgcgccc aggccaccgc tttcaggtaa tcgtcaaagt attccgtacc ttccataaag
    58861 tacgccagat cacgcgacgg caacgtttca agtgtttcct gcatctcttt ttgcgccaga
    58921 tcgataaaat aagttccgat ggcgttacca attccgcgtg aaccggagtg cagcataatc
    58981 tacacctggt ccgactcatc aaggcagatt tcaataaagt ggttacccgt tcccagcgtt
    59041 cccagatgtt tatagttgtt agtgttaagg aaacgtggat atttttgcgt taaccactga
    59101 taaccggctt ccagctcagc ccatttcgca tcgacgttaa caggcggatt ttcccatgcg
    59161 cctttatcac gtttacaacg tccggtagta cgcccgtgcg gcacggcagc ttcaatcgcc
    59221 tgacgcagct ccgccaggtt ttccggcagg tctgccgccg ttaacgcggt acgcagcgcg
    59281 ttcattccac aaccgatatc tacccccacc gccgccggaa taatcgcccc tttggttggg
    59341 atcacgctac caatggtgga acctttaccc agatgtacat caggcattac cgcaatatgt
    59401 ttgaaaataa acggcatctt cgccgtattt atcagttgct gacgcgcatc gtcttctacc
    59461 ggtacgcctt tggtccacat ttttaccggg acattttcag tggtcagtaa ttcgtaattc
    59521 attttgtttt tctcttt
//
LOCUS       DADXDL010000017        57103 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.017, whole genome shotgun sequence.
ACCESSION   DADXDL010000017 DADXDL010000000
VERSION     DADXDL010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 57103)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 57103)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..57103
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.017"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..402
                     /locus_tag="IRB70_001342"
     CDS             <1..402
                     /locus_tag="IRB70_001342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3289 family protein"
                     /protein_id="HBC0631282.1"
                     /translation="IIKECIENGINSTPSTGYQPLILQSIKTKLLSSRLNKFNDFEDS
                     FNGLGISVHDISAQKISLLSFQKYAIGWSATIHFVAQDHFGLDVTDIKNKTYSKYRFF
                     RIWFFLQRHKDFAFKPFFTNFNTIERIENYL"
     gene            399..896
                     /locus_tag="IRB70_001343"
     CDS             399..896
                     /locus_tag="IRB70_001343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF943 family protein"
                     /protein_id="HBC0631283.1"
                     /translation="MKSKLQKIILYLFLLCCIYNLWTLRPVQILYTYSDAGNSVFLVV
                     DHLPWTDSDKINWYLKHQNEIKNQHPLPEGSWHTWYVIDIGNGFTDYKKYIEGPYEDL
                     YCFPTIKSNDNCIVKNYLMVINEYPYRNTHFFIADNNEYQLTQENKIERVFNPHDFEK
                     DNFQQ"
     gene            complement(932..1882)
                     /gene="corA"
                     /locus_tag="IRB70_001344"
     CDS             complement(932..1882)
                     /gene="corA"
                     /locus_tag="IRB70_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000947142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium/cobalt transporter CorA"
                     /protein_id="HBC0631284.1"
                     /translation="MLSAFQLENNRLTRLEVEESQPLVNAVWIDLVEPDDDERLRVQS
                     ELGQSLATRPELEDIEASARFFEDDDGLHIHSFFFFEDAEDHAGNSTVAFTIRDGRLF
                     TLRERELPAFRLYRMRARSQSMVDGNAYELLLDLFETKIEQLADEIENIYSDLEQLSR
                     VIMEGHQGDEYDEALSTLAELEDIGWKVRLCLMDTQRALNFLVRKARLPGGQLEQARE
                     ILRDIESLLPHNESLFQKVNFLMQAAMGFINIEQNRIIKIFSVVSVVFLPPTLVASSY
                     GMNFEFMPELKWSFGYPGAIIFMILAGLAPYLYFKRKNWL"
     gene            2252..3016
                     /locus_tag="IRB70_001345"
     CDS             2252..3016
                     /locus_tag="IRB70_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiester glycosidase family protein"
                     /protein_id="HBC0631285.1"
                     /translation="MAHRLLIGKGMITLNLKRIFLTFTLLPLFAVAADDCALSDPTLT
                     VQAYTVNPQTERVKMYWQKANGEAWGTLHALLADMNSQGQVQMAMNGGIYDESYAPLG
                     LYIENGQQKVALNLASGEGNFFIRPGGVFYVAGDKVGIVRLDAFKTSKEIQFAVQSGP
                     MLLENGVINPRIHPNVASRKIRNGVGINKQGNAVFLLSQQPTNFYDFACYAKAKLNVE
                     QLLYLDGTISHMYMKGGAIPWQRYPFVTMISVERKG"
     gene            3099..4001
                     /locus_tag="IRB70_001346"
     CDS             3099..4001
                     /locus_tag="IRB70_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-adenosyl-l-methionine hydroxide
                     adenosyltransferase family protein"
                     /protein_id="HBC0631286.1"
                     /translation="MKKTLATLFLLTCLGSSSAYADNALILQTDFSLKDGAVSAMKGV
                     AFGVDHNLKIFDLTHEIPPYNIWEGAYRLYQTASYWPQGSVFVSVVDPGVGTDRKSVV
                     LKTKNGQYFVSPDNGTLTLVAQTLGIDSVREIDEKANRLKGSEKSYTFHGRDVYAYTG
                     ARLASGVITFEQVGPELPAKVVELSYQKAKATKGEVKGNIPILDIQYGNVWSNISDEL
                     LNQAGIKLNDTLCVTISEGSQQKYAGKMPYVASFGDVPEGQPMVYLNSLLNVSVALNM
                     DNFAQKHQVASGADWNIDVKKCAK"
     gene            complement(4056..6218)
                     /gene="uvrD"
                     /locus_tag="IRB70_001347"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
     CDS             complement(4056..6218)
                     /gene="uvrD"
                     /locus_tag="IRB70_001347"
                     /gene_synonym="mutU"
                     /gene_synonym="recL"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase II"
                     /protein_id="HBC0631287.1"
                     /translation="MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVLVHRIA
                     WLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLMGTSQGGMWVGTFHGLAHRLLRAHH
                     MDANLPQDFQILDSEDQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRPHHIQ
                     SYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLRAHELWLNKPHILQHYRERFTNIL
                     VDEFQDTNNIQYAWIRLLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPGAET
                     IRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDGADGEPISLYCAFNELDEARFVV
                     NRIKTWQDNGGALAECAILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKDAL
                     SYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQTSRDRQLTLWQACRELLQEKAL
                     AGRAASALQRFMELIDALAQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIEN
                     LEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQADTWQDAVQLMTLHSAKGLE
                     FPQVFIVGMEEGMFPSQMSLDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
                     VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPMVENDSGYKLGQRVRHAKFG
                     EGTIVNMEGSGEHSRLQVAFQGQGIKWLVAAYARLETV"
     gene            complement(6302..7018)
                     /gene="yigB"
                     /locus_tag="IRB70_001348"
     CDS             complement(6302..7018)
                     /gene="yigB"
                     /locus_tag="IRB70_001348"
                     /EC_number="3.1.3.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-amino-6-(5-phospho-D-ribitylamino)uracil
                     phosphatase YigB"
                     /protein_id="HBC0631288.1"
                     /translation="MRFYRPLGRISALTFDLDDTLYDNRPVILRTEREALTFVQNYHP
                     ALRSFQNEDLQRLRQAVREAEPEIYHDVTRWRFRSIEQAMLDAGLSAEEASAGAHAAM
                     INFAKWRSRIDVPQQTHDTLKQLAKKWPLVAITNGNAQPELFGLGDYFEFVLRAGPHG
                     RSKPFSDMYFLAAEKLNVPIGEILHVGDDLTTDVGGAIRSGMQACWIRPENGDLMQTW
                     DSRLLPHLEISRLASLTSLI"
     gene            complement(7018..7914)
                     /gene="xerC"
                     /locus_tag="IRB70_001349"
     CDS             complement(7018..7914)
                     /gene="xerC"
                     /locus_tag="IRB70_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBC0631289.1"
                     /translation="MTDLHTDVERYLRYLSVERQLSPITLLNYQRQLEAIINFASENG
                     LQSWQQCDVTMVRNFAVRSRRKGLGAASLALRLSALRSFFDWLVSQNELKANPAKGVS
                     APKAPRHLPKNIDVDDMNRLLDIDINDPLAVRDRAMLEVMYGAGLRLSELVGLDIKHL
                     DLESGEVWVMGKGSKERRLPIGRNAVAWIEHWLDLRDLFGSEDDALFLSKLGKRISAR
                     NVQKRFAEWGIKQGLNNHVHPHKLRHSFATHMLESSGDLRGVQELLGHANLSTTQIYT
                     HLDFQHLASVYDAAHPRAKRGK"
     gene            complement(7911..8618)
                     /locus_tag="IRB70_001350"
     CDS             complement(7911..8618)
                     /locus_tag="IRB70_001350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF484 domain-containing protein"
                     /protein_id="HBC0631290.1"
                     /translation="MKQPGEELQETLTELDDRAVVDYLIKNPEFFIRNARAVEAIRVP
                     HPVRGTVSLVEWHMARARNHIHVLEENMALLMEQAIANEGLFYRLLYLQRSLTAASSL
                     DDMLMRFHRWARDLGLAGASLRLFPDRWRLGAPSNHTHLALSRQSFEPLRIQRLGQEQ
                     HYLGPLNGPELLVVLPEAKAVGSVAMSMLGSDADLGVVLFTSRDASHYQQGQGTQLLH
                     EIALMLPELLERWIERV"
     gene            complement(8615..9439)
                     /gene="dapF"
                     /locus_tag="IRB70_001351"
     CDS             complement(8615..9439)
                     /gene="dapF"
                     /locus_tag="IRB70_001351"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBC0631291.1"
                     /translation="MQFSKMHGLGNDFMVVDAVTQNVFFSPELIRRLADRHLGVGFDQ
                     LLVVEPPYDPELDFHYRIFNADGSEVAQCGNGARCFARFVRLKGLTNKRDIRVSTANG
                     RMVLTVTDDDLVRVNMGEPNFEPSAVPFRANKAEKTYIMRAAEQTILCGVVSMGNPHC
                     VIQVDDVDTAAVETLGPVLESHERFPERANIGFMQVVKREHIRLRVYERGAGETQACG
                     SGACAAVAVGIQQGLLAEEVRVELPGGRLDIAWKGPGHPLYMTGPAVHVYDGFIHL"
     gene            complement(9476..9679)
                     /locus_tag="IRB70_001352"
     CDS             complement(9476..9679)
                     /locus_tag="IRB70_001352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBC0631292.1"
                     /translation="MKNVFKALTVLLTLFSLTGCGLKGPLYFPPADKNAPPPTKPVET
                     QTQSTVPDKNDRATGDGPSQVNY"
     gene            9838..10023
                     /locus_tag="IRB70_001353"
                     /pseudo
     CDS             9838..10023
                     /locus_tag="IRB70_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580503.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DKNYY family protein"
     gene            10149..10469
                     /gene="cyaY"
                     /locus_tag="IRB70_001354"
     CDS             10149..10469
                     /gene="cyaY"
                     /locus_tag="IRB70_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000999950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron donor protein CyaY"
                     /protein_id="HBC0631293.1"
                     /translation="MNDSEFHRLADQLWLTIEERLDDWDGDSDIDCEINGGVLTITFE
                     NGSKIIINRQEPLHQVWLATKQGGYHFDMKGDEWICDRSGETFWDLLEQAATQQAGET
                     VSFR"
     gene            complement(10509..13055)
                     /gene="cyaA"
                     /locus_tag="IRB70_001355"
     CDS             complement(10509..13055)
                     /gene="cyaA"
                     /locus_tag="IRB70_001355"
                     /EC_number="4.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I adenylate cyclase"
                     /protein_id="HBC0631294.1"
                     /translation="MYLYIETLKQRLDAINQLRVDRALAAMGPAFQQVYSLLPTLLHY
                     HHPLMPGYLDGNVPKGICLYTPDETQRHYLNELELYRGMSVQDPPKGELPITGVYTMG
                     STSSVGQSCSSDLDIWVCHQSWLDSEERQLLQRKCSLLESWAASLGVEVSFFLIDENR
                     FRHNESGSLGGEDCGSTQHILLLDEFYRTAVRLAGKRILWNMVPCDEEEHYDDYVMTL
                     YAQGVLTPNEWLDLGGLSSLSAEEYFGASLWQLYKSIDSPYKAVLKTLLLEAYSWEYP
                     NPRLLAKDIKQRLHDGEIVSFGLDPYCMMLERVTEYLTAIEDFTRLDLVRRCFYLKVC
                     EKLSRERACVGWRREVLTQLVKEWEWDDARLAMLDNRANWKIDQVREAHNELLDAMMQ
                     SYRNLIRFARRNNLSVSASPQDIGVLTRKLYAAFEALPGKVTLVNPQISPDLSEPNLT
                     FIYVPPGRANRSGWYLYNRAPNIESIISHQPLEYNRYLNKLVAWAWFNGLLTSRTRLY
                     IKGNGIVDLPKLQEMVADVSHHFPLRLPAPTPKALYSPCEIRHLAIIVNLEYDPTAAF
                     RNQVVHFDFRKLDVFSFGENQNCLVGSVDLLYRNSWNEVRTLHFNGEQSMIEALKTIL
                     GKMHQDAAPPDSVEVFCYSQHLRGLIRTRVQQLVSECIELRLSSTRQETGRFKALRVS
                     GQTWGLFFERLNVSVQKLENAIEFYGAISHNKLHGLSVQVETNHVKLPAVVDGFASEG
                     IIQFFFEETQDENGFNIYILDESNRVEVYHHCEGSKEELVRDVSRFYSSSHDRFTYGS
                     SFINFNLPQFYQIVKVDGREQVIPFRTKSIGNMPPANQDHDTPLLQQYFS"
     gene            13442..14383
                     /gene="hemC"
                     /locus_tag="IRB70_001356"
     CDS             13442..14383
                     /gene="hemC"
                     /locus_tag="IRB70_001356"
                     /EC_number="2.5.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylbilane synthase"
                     /protein_id="HBC0631295.1"
                     /translation="MLDNVLRIATRQSPLALWQAHYVKDKLMASHPGLVVELVPMVTR
                     GDVILDTPLAKVGGKGLFVKELEVALLENRADIAVHSMKDVPVEFPQGLGLVTICERE
                     DPRDAFVSNNYESLDALPAGSIVGTSSLRRQCQLAERRPDLIIRSLRGNVGTRLSKLD
                     NGEYDAIILAVAGLKRLGLESRIRAALPPEISLPAVGQGAVGIECRLDDTRTRELLAA
                     LNHHETALRVTAERAMNTRLEGGCQVPIGSYAELIDGEIWLRALVGAPDGSQIIRGER
                     RGAPQDAEQMGISLAEELLNNGAREILAEVYNGDAPA"
     gene            14380..15120
                     /gene="hemD"
                     /locus_tag="IRB70_001357"
     CDS             14380..15120
                     /gene="hemD"
                     /locus_tag="IRB70_001357"
                     /EC_number="4.2.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III synthase"
                     /protein_id="HBC0631296.1"
                     /translation="MSILVTRPSPAGEELVSRLRTLGQVAWHFPLIEFSPGRQLPQLA
                     DQLAALGESDLLFALSQHAVAFAQSQLHQQDRKWPRLPDYFAIGRTTALALHTVSGQK
                     ILYPQDREISEVLLQLPELQNIAGKRALILRGNGGRELIGDTLTARGAEVTFCECYQR
                     CAIHYDGAEEAMRWQSREVTTVVVTSGEMLQQLWSLIPQWYREHWLLHCRLLVVSERL
                     AKLARELGWQDIKVADNADNDALLRALQ"
     gene            15142..16365
                     /gene="hemX"
                     /locus_tag="IRB70_001358"
     CDS             15142..16365
                     /gene="hemX"
                     /locus_tag="IRB70_001358"
                     /EC_number="2.1.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen-III C-methyltransferase"
                     /protein_id="HBC0631297.1"
                     /translation="MTEQEKTSAVVEETREAVDTTSQPVATEKKSKNNTALILSAVAI
                     AIALAAGVGLYGWGKQQAVNQTATSDALANQLTALQKAQESQKAELEGIIKQQAVQLE
                     QANRQQETLAKQLDEVQQKVATISGSDAKTWLLAQADFLVKLAGRKLWSDQDVTTAAA
                     LLKSADASLADMNDPSLITVRRAITDDIASLSAVSQVDYDGIILKLNQLSNQVDNLRL
                     ADNDSDGSPMDSDGEELSSSISEWRINLQKSWQNFMDNFITIRRRDDTAVPLLAPNQD
                     IYLRENIRSRLLVAAQAVPRHQEETYRQALENVSTWVRAYYDTDDATTKAFLDEVDQL
                     SQQNISMDLPETLQSQAMLEKLMQTRVRNLLAQPAAGTTEAKPAPAPAPAPAPAPAPA
                     PAPQADTPAAAPQGE"
     gene            16368..17564
                     /gene="hemY"
                     /locus_tag="IRB70_001359"
     CDS             16368..17564
                     /gene="hemY"
                     /locus_tag="IRB70_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protoheme IX biogenesis protein HemY"
                     /protein_id="HBC0631298.1"
                     /translation="MLKVLLLFVLLIAGIVVGPMIAGHQGYVLIQTDNYNIETSVTGL
                     AIILILAMVVLFAIEWLLRRIFRTGAHTRGWFVGRKRRRARKQTEQALLKLAEGDYQQ
                     VEKLMAKNADHAEQPVVNYLLAAEAAQQRGDEARANQHLERAAELAGNGTIPVEITRV
                     RLQLARNENHAARHGVDKLLEVTPRHPEVLRLAEQAYIRTGAWSSLLDIIPSMAKAHV
                     GDEEHRAMLEQQAWIGLMDQARADNGSEGLRNWWKNQSRKTRHQVALQVAMAEHLIEC
                     DDHDTAQQIIIDGLKRQYDDRLLLPIPRLKTNNPEQLEKVLRQQIKNVGDRPLLWSTL
                     GQSLMKHGEWQEASLAFRAALKQRPDAYDYAWLADALDRLHKPEEAAAMRRDGLMLTL
                     QNNPSQ"
     gene            17614..18204
                     /locus_tag="IRB70_001360"
     CDS             17614..18204
                     /locus_tag="IRB70_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001260226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631299.1"
                     /translation="MRTPSRYLFRLPSHEITPFRATLFLILLICAALAGVSWLIISFV
                     RTGNTFIFWLTLFIGYLIAAAKQEKIKILKKYRIMADKRRGRSICQFAREFDTYTVDT
                     WVIRAVWDTLQGNGYIDYPLPLKADDILDDDLDLVSDAVELEELVEDTAARCGRDLCG
                     IEENPFLPIVTVGSLVRVLNAQPMTQERRNQFFIRS"
     gene            18819..20474
                     /gene="aslA"
                     /locus_tag="IRB70_001361"
     CDS             18819..20474
                     /gene="aslA"
                     /locus_tag="IRB70_001361"
                     /EC_number="3.1.6.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arylsulfatase AslA"
                     /protein_id="HBC0631300.1"
                     /translation="MEFSFSPKLLVVAVAAALPLMANAADTPSTATARKGFAGYDHPN
                     QYLVKPATTIADNMMPVMQHPAQDKETQQKLAELEKKTGKKPNVVVFLLDDVGWMDVG
                     FNGGGVAVGNPTPDIDAVASQGLILTSAYSQPSSSPTRATILTGQYSIHHGILMPPMY
                     GQPGGLQGLTTLPQLLHDQGYVTQAIGKWHMGENKESQPQNVGFDDFRGFNSVSDMYT
                     EWRDVHVNPEVALSPDRSEYIQKLPFSKDDVHAVRGGEQEAIADITPKYMEDLDQRWM
                     EYGVKFLDKMAKSDKPFFLYYGTRGCHFDNYPNAKYAGSSPARTSYGDCMVEMNDIFA
                     NLYKALEKNGQLDNTLIVFTSDNGPEAEVPPHGRTPFRGAKGSTWEGGVRVPTFVYWK
                     GMIQPRKSDGIVDLADLFPTALDLAGHPGAKVANLVPKTTFIDGVDQTSFFLGTNGQS
                     NRKAEHYFLNGKLSAVRMDEFKYHVLIQQPYAYTQSGYQGGFTGTVMQTAGSSVFNLY
                     TDPQESDSIGVRHIPMGVPLQTEMHAYMEILKKYPPRAQIKSD"
     gene            complement(20632..21867)
                     /locus_tag="IRB70_001362"
     CDS             complement(20632..21867)
                     /locus_tag="IRB70_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HBC0631301.1"
                     /translation="MLQQVPTRAFHVMAKPSGSDCNLNCDYCFYLEKQSLYREKPVTH
                     MDDDTLEAYVRHYIAASETQNEVAFTWQGGEPTLLGLDFYRRAVALQAKYGAGRKISN
                     SFQTNGVLLDDEWCAFLAENHFLVGLSLDGPAEIHNQYRVTKGGRPTHKLVMRALTLL
                     QKHHVDYNVLVCVNRTSALQPLQIYDFLCDAGVEFIQFIPVVERLADETAAHAGLKLH
                     APGDIQGELTEWSVRPDEFGEFLVAIFDHWIKRDVGKIFVMNIEWAFANFVGAPGAVC
                     HHQPTCGRSVIVEHNGDVYACDHYVYSQYRLGNMLQQTIAEMVDSPQQQVFGEDKFKQ
                     LPAQCRSCNVLKACWGGCPKHRFMLDASGKPGLNYLCAGYQRYFRHLPPYLKAMADLL
                     AHGRPASDIMQAHLMVVNK"
     gene            complement(22014..22090)
                     /locus_tag="IRB70_001363"
     tRNA            complement(22014..22090)
                     /locus_tag="IRB70_001363"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22054..22056),aa:Pro,seq:tgg)
     gene            complement(22133..22219)
                     /locus_tag="IRB70_001364"
     tRNA            complement(22133..22219)
                     /locus_tag="IRB70_001364"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22183..22185),aa:Leu,seq:cag)
     gene            complement(22240..22315)
                     /locus_tag="IRB70_001365"
     tRNA            complement(22240..22315)
                     /locus_tag="IRB70_001365"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22280..22282),aa:His,seq:gtg)
     gene            complement(22374..22450)
                     /locus_tag="IRB70_001366"
     tRNA            complement(22374..22450)
                     /locus_tag="IRB70_001366"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(22414..22416),aa:Arg,seq:ccg)
     gene            complement(22553..23938)
                     /locus_tag="IRB70_001367"
     CDS             complement(22553..23938)
                     /locus_tag="IRB70_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBC0631302.1"
                     /translation="MADNKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPS
                     VLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMA
                     VGISEITAIGVYVQFWFPEMAQWIPALIAVALVALANLAAVRLYGEIEFWFAMIKVTT
                     IIVMIVIGLGVIFFGFGNGGQSIGFSNLTEHGGFFAGGWKGFLTALCIVVASYQGVEL
                     IGITAGEAKNPQVTLRSAVGKVLWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFA
                     KIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPAAMAKVSRHGVPVA
                     GVAVSIAILLIGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKAA
                     IASHPFRSILFPWANYVTMAFLICVLIGMYFNEDTRMSLFVGIIFMLAVTAIYKIFGL
                     NRHGKAHKLEE"
     gene            complement(24129..24869)
                     /gene="rffM"
                     /locus_tag="IRB70_001368"
     CDS             complement(24129..24869)
                     /gene="rffM"
                     /locus_tag="IRB70_001368"
                     /EC_number="2.4.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide
                     N-acetylmannosaminouronosyltransferase"
                     /protein_id="HBC0631303.1"
                     /translation="MNNTTTAPTYTLRGLQLIGWRDMQHALDYLFADGQLKQGTLVAI
                     NAEKMLTIEDNAEVRELINAAEFKYADGISVVRSVRKKYPQAQVSRVAGADLWEELMA
                     RAGKEGTPVFLVGGKPEVLAQTEAKLRNQWNVNIVGSQDGYFKPEQRQALFERIHASG
                     AQIVTVAMGSPKQEIFMRDCRLVHPDALYMGVGGTYDVFTGHVKRAPKIWQTLGLEWL
                     YRLLSQPSRIKRQLRLLRYLRWHYTGNL"
     gene            complement(24872..26224)
                     /gene="wzyE"
                     /locus_tag="IRB70_001369"
     CDS             complement(24872..26224)
                     /gene="wzyE"
                     /locus_tag="IRB70_001369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA oligosaccharide polymerase"
                     /protein_id="HBC0631304.1"
                     /translation="MSLLQFSGLFVVWLLCTLFIATLTWFEFRRVRFNFNVFFSLLFL
                     LTFFFGFPLTSVLVFRFDVGVAPPEILLQALLSAGCFYAVYYVTYKTRLRKRVADAPR
                     RPLFTMNRVETNLTWVILMGIALVSVGIFFMHNGFLLFRLNSYSQIFSSEVSGVALKR
                     FFYFFIPAMLVVYFLRQDSKAWLFFLVSTVAFGLLTYMIVGGTRANIIIAFAIFLFIG
                     IIRGWISLWMLAAAGVLGIVGMFWLALKRYGMNVSGDEAFYTFLYLTRDTFSPWENLA
                     LLLQNYDNIDFQGLAPIVRDFYVFIPSWLWPGRPSMVLNSANYFTWEVLNNHSGLAIS
                     PTLIGSLVVMGGALFIPLGAIVVGLIIKWFDWLYELGNRETNRYKAAILHSFCFGAIF
                     NMIVLAREGLDSFVSRVVFFIVVFGACLMIAKLLYWLFESAGLIHKRTKSSLRTQIEG
                     "
     gene            complement(26221..27300)
                     /gene="rffT"
                     /locus_tag="IRB70_001370"
                     /gene_synonym="wecF"
     CDS             complement(26221..27300)
                     /gene="rffT"
                     /locus_tag="IRB70_001370"
                     /gene_synonym="wecF"
                     /EC_number="2.4.1.325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDP-N-acetylfucosamine:lipid II
                     N-acetylfucosaminyltransferase"
                     /protein_id="HBC0631305.1"
                     /translation="MTVLIHVLGSDIPHHNRTVLRFFNDALAATSEHAREFMVVGKDD
                     GLSDSCPALSVQFFPGKKSLAEAVIAKAKANRQQRFFFHGQFNPKLWLALLSGGIKPS
                     QFFWHIWGADLYELSSGLRYKLFYPLRRLAQKRVGCVFATRGDLSFFAKTHPKVRGEL
                     LYFPTRMDPSLNTMANDRQCEGKMTILVGNSGDRSNEHIAVLRAVHQQFGDTVKVVVP
                     MGYPPNNEAYIEEVRQAGLELFSEENLQVLSEKLEFDAYLTLLRQCDLGYFIFARQQG
                     IGTLCLLIQAGIPCVLNRENPFWQDMTEQHLPVLFTTDDLNEDIVREAQRQLASVDKN
                     TIAFFSPNYLQGWQRALAIATGEVA"
     gene            complement(27297..28547)
                     /gene="wzxE"
                     /locus_tag="IRB70_001371"
     CDS             complement(27297..28547)
                     /gene="wzxE"
                     /locus_tag="IRB70_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid III flippase WzxE"
                     /protein_id="HBC0631306.1"
                     /translation="MSLAKASLWTAASTLVKIGAGLLVGKLLAVSFGPAGLGLAANFR
                     QLITVLGVLAGAGIFNGVTKYVAQYHDNPQQLRRVVGTSSAMVLGFSMLMALVFVLAA
                     APISQGLFGNTDYQGLVRLVALVQMGIAWGNLLLALMKGFRDAAGNALSLIVGSLIGV
                     LAYYVSYRLGGYEGALLGLALIPALVVIPAAIMLIKRGVIPLSYLKPSWDNGLAGQLS
                     KFTLMALITSVTLPVAYIMMRKLLAAQYSWDEVGIWQGVSSISDAYLQFITASFSVYL
                     LPTLSRLTEKRDITREVVKSLKFVLPAVAAASFTVWLLRDFAIWLLLSNKFTAMRDLF
                     AWQLVGDVLKVGAYVFGYLVIAKASLRFYILAEISQFTLLMVFAHWLIPAHGALGAAQ
                     AYMATYIVYFSLCCGVFLLWRRRA"
     gene            complement(28549..29679)
                     /gene="rffA"
                     /locus_tag="IRB70_001372"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
     CDS             complement(28549..29679)
                     /gene="rffA"
                     /locus_tag="IRB70_001372"
                     /gene_synonym="fcnA"
                     /gene_synonym="wecE"
                     /EC_number="2.6.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxygalactose transaminase"
                     /protein_id="HBC0631307.1"
                     /translation="MIPFNAPPVVGTELDYMQSAMGSGKLCGDGGFTRRCQQWLEQRF
                     GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAFVLRGAKIVFVDVRP
                     DTMNIDETLIEAAITDKTRVIVPVHYAGVACEMDTIMALAKKHNLFVVEDAAQGVMST
                     YKGRALGTIGHIGCFSFHETKNYTAGGEGGATLINDKALIERAEIIREKGTNRSQFFR
                     GQVDKYTWRDIGSSYLMSDLQAAYLWAQLEAADRINQQRLALWQNYYDALAPLAKAGR
                     IELPSIPDGCVQNAHMFYIKLRDIDDRSALINFLKEAEIMAVFHYIPLHGCPAGERFG
                     EFHGEDRYTTKESERLVRLPLFYNLSPVNQRTVIATLLNYFS"
     gene            complement(29684..30358)
                     /gene="rffC"
                     /locus_tag="IRB70_001373"
                     /gene_synonym="wecD"
     CDS             complement(29684..30358)
                     /gene="rffC"
                     /locus_tag="IRB70_001373"
                     /gene_synonym="wecD"
                     /EC_number="2.3.1.210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-amino-4,6-dideoxy-D-galactose
                     acyltransferase"
                     /protein_id="HBC0631308.1"
                     /translation="MPVRASIEPLTWENAFFGVNSAIVRITTEAPLLTSDALAPWSRV
                     QAKIAASNTGELDALQQLGFSLVEGEVDLALPVNNVSDSGAVVAQETDIPALRQLASA
                     AFAQSRFRAPWYAPDASGRFYAQWIENAVRGTFDHQCLILRAASGDIRGYVSLRELNA
                     TDARIGLLAGRGAGAELMQTALNWAYARGKTTLRVATQMGNTAALKRYIQSGANVEST
                     AYWLYR"
     gene            complement(30336..31217)
                     /gene="rfbA"
                     /locus_tag="IRB70_001374"
     CDS             complement(30336..31217)
                     /gene="rfbA"
                     /locus_tag="IRB70_001374"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBC0631309.1"
                     /translation="MKGIILAGGSGTRLHPITRGVSKQLLPIYDKPMIYYPLSVLMLA
                     GIREILIITTPEDKGYFQRLLGDGSEFGIQLEYAEQPSPDGLAQAFIIGETFLNGEPS
                     CLVLGDNIFFGQGFSPKLRHVAARTEGATVFGYQVMDPERFGVVEFDDNFRAISLEEK
                     PKQPKSNWAVTGLYFYDSKVVEYAKQVTPSERGELEITSINQMYLEAGNLTVELLGRG
                     FAWLDTGTHDSLIEASTFVQTVEKRQGFKIACLEEIAWRNGWLDDEGVKRAASSLAKT
                     GYGQYLLELLRARPRQY"
     gene            complement(31236..32303)
                     /gene="rffG"
                     /locus_tag="IRB70_001375"
     CDS             complement(31236..32303)
                     /gene="rffG"
                     /locus_tag="IRB70_001375"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBC0631310.1"
                     /translation="MRKILITGGAGFIGSALVRYIINETSDAVIVVDKLTYAGNLMSL
                     APVAQSERFAFEKVDICDRAELARVFTEYQPDCVMHLAAESHVDRSIDGPAAFIETNI
                     VGTYTLLEAARTYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSPY
                     SASKASSDHLVRAWLRTYGLPTLITNCSNNYGPYHFPEKLIPLMILNALAGKPLPVYG
                     NGQQIRDWLYVEDHARALYCVATTGKVGETYNIGGHNERKNLDVVETICELLEELAPN
                     KPHGVAHYRDLITFVADRPGHDLRYAIDASKIARELGWLPQETFESGMRKTVQWYLAN
                     EIWWKQVQDGSYQGERLGLKG"
     gene            complement(32303..33565)
                     /gene="wecC"
                     /locus_tag="IRB70_001376"
     CDS             complement(32303..33565)
                     /gene="wecC"
                     /locus_tag="IRB70_001376"
                     /EC_number="1.1.1.336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetyl-D-mannosamine dehydrogenase"
                     /protein_id="HBC0631311.1"
                     /translation="MSFATISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINR
                     GEIHIAEPDLASVVKTAVEGGFLRASTTPVEADAWLIAVPTPFKGDHEPDMTYVESAA
                     RSIAPVLKKGALVILESTSPVGSTEKMAEWLAEMRPDLTFPQQVGELADVNIAYCPER
                     VLPGQVMVELIKNDRVIGGMTPVCSARASELYKIFLEGECVVTNSRTAEMCKLTENSF
                     RDVNIAFANELSLICADQGINVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVA
                     QNPQQARLIRTAREVNDHKPFWVIDQVKAAVADCLAATDKRASELKIACFGLAFKPNI
                     DDLRESPAMEIAELIAQWHSGETLVVEPNIHQLPKKLTGLCTLAQLDEALATADVLVM
                     LVDHSQFKVINGDNVHQQYVVDAKGVWR"
     gene            complement(33562..34692)
                     /gene="wecB"
                     /locus_tag="IRB70_001377"
     CDS             complement(33562..34692)
                     /gene="wecB"
                     /locus_tag="IRB70_001377"
                     /EC_number="5.1.3.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (non-hydrolyzing)"
                     /protein_id="HBC0631312.1"
                     /translation="MKVLTVFGTRPEAIKMAPLVHALAKDPFFEAKVCVTAQHREMLD
                     QVLKLFSIVPDYDLNIMQPGQGLTEITCRILEGLKPILAEFKPDVVLVHGDTTTTLAT
                     SLAAFYQRIPVGHVEAGLRTGDLYSPWPEEANRTLTGHLAMYHFSPTETSRQNLLREN
                     VADSRIFITGNTVIDALLWVRDQVMSSDTLRSELAANYPFIDPDKKMILVTGHRRESF
                     GRGFEEICQALADIAITHQDIQIVYPVHLNPNVREPVNRILGHVKNVILIDPQEYLPF
                     VWLMNHAWLILTDSGGIQEEAPSLGKPVLVMRDTTERPEAVTAGTVRLVGTDKQRIVE
                     EVTRLLKDENEYQAMSRAHNPYGDGQACSRILEALKNNRISL"
     gene            complement(34748..35794)
                     /gene="wzzE"
                     /locus_tag="IRB70_001378"
     CDS             complement(34748..35794)
                     /gene="wzzE"
                     /locus_tag="IRB70_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709589.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECA polysaccharide chain length modulation
                     protein"
                     /protein_id="HBC0631313.1"
                     /translation="MTQPMPGKPAEDAENELDIRGLFRTLWAGKLWIIGMGLAFALIA
                     LAYTFFARQEWSSTAITDRPTVNMLGGYYSQQQFLRNLDVRSNMASADQPSVMDEAYK
                     EFVMQLASWDTRREFWLQTDYYKQRMVGNSKADAALLDEMINNIVFIPGDFTRAVNDS
                     VKLIAETAPDANNLLRQYVAFASQRAASHLNDELKGAWAARTIQMKAQVKRQEEVAKA
                     IYDRRMNSIEQALKIAEQHNISRSATDVPAEELPDSEMFLLGRPMLQARLENLQAVGP
                     AFDLDYDQNRAMLNTLNVGPTLDPRFQTYRYLRTPEEPVKRDSPRRAFLMIMWGIVGG
                     LIGAGVALTRRCSK"
     gene            complement(35806..36909)
                     /gene="wecA"
                     /locus_tag="IRB70_001379"
     CDS             complement(35806..36909)
                     /gene="wecA"
                     /locus_tag="IRB70_001379"
                     /EC_number="2.7.8.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine--undecaprenyl-phosphate
                     N-acetylglucosaminephosphotransferase"
                     /protein_id="HBC0631314.1"
                     /translation="MNLLTVSTDLISIFLFTTLFLFFARKVAKKVGLVDKPNFRKRHQ
                     GLIPLVGGISVYAGICFTFGIVDYYIPHASLYLACAGVLVFIGALDDRFDISVKIRAT
                     IQAAVGIVMMVFGKLYLSSLGYIFGSWEMVLGPFGYFLTLFAVWAVINAFNMVDGIDG
                     LLGGLSCVSFAAIGMILWFDGQTSLAIWCFAMIAAILPYIMLNLGILGRRYKVFMGDA
                     GSTLIGFTVIWILLETTQGKTHPISPVTALWIIAIPLMDMVAIMYRRLRKGMSPFSPD
                     RQHIHHLIMRAGFTSRQAFVLITLAAALLASIGVLAEYSHFVPEWVMLVLFLLAFFLY
                     GYCIKRAWKVARFIKRVKRRLRRNRGGSPNLTK"
     gene            complement(37137..38396)
                     /gene="rho"
                     /locus_tag="IRB70_001380"
     CDS             complement(37137..38396)
                     /gene="rho"
                     /locus_tag="IRB70_001380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017492510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBC0631315.1"
                     /translation="MNLTELKNTPVSELITLGENMGLENLARMRKQDIIFAILKQHAK
                     SGEDIFGDGVLEILQDGFGFLRSADSSYLAGPDDIYVSPSQIRRFNLRTGDTISGKIR
                     PPKEGERYFALLKVNEVNFDKPENARNKILFENLTPLHANSRLRMERGNGSTEDLTAR
                     VLDLASPIGRGQRGLIVAPPKAGKTMLLQNIAQSIAYNHPDCVLMVLLIDERPEEVTE
                     MQRLVKGEVVASTFDEPASRHVQVAEMVIEKAKRLVEHKKDVIILLDSITRLARAYNT
                     VVPASGKVLTGGVDANALHRPKRFFGAARNVEEGGSLTIIATALIDTGSKMDEVIYEE
                     FKGTGNMELHLSRKIAEKRVFPAIDYNRSGTRKEELLTTQEELQKMWILRKIIHPMGE
                     IDAMEFLINKLAMTKTNDDFFEMMKRS"
     gene            complement(38481..38582)
                     /gene="rhoL"
                     /locus_tag="IRB70_001381"
     CDS             complement(38481..38582)
                     /gene="rhoL"
                     /locus_tag="IRB70_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rho operon leader peptide RhoL"
                     /protein_id="HBC0631316.1"
                     /translation="MRSEQISGSSLNPSCRFSSAYSPVTRQRKDMSR"
     gene            complement(38723..39052)
                     /gene="trxA"
                     /locus_tag="IRB70_001382"
     CDS             complement(38723..39052)
                     /gene="trxA"
                     /locus_tag="IRB70_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017375425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin TrxA"
                     /protein_id="HBC0631317.1"
                     /translation="MSDKIIHLTDDSFDTDVLKADGAILVDFWAEWCGPCKMIAPILD
                     EIADEYQGKLTVAKLNIDQNPGTAPKYGIRGIPTLLLFKNGEVAATKVGALSKGQLKE
                     FLDANLA"
     gene            39183..40448
                     /gene="rhlB"
                     /locus_tag="IRB70_001383"
     CDS             39183..40448
                     /gene="rhlB"
                     /locus_tag="IRB70_001383"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase RhlB"
                     /protein_id="HBC0631318.1"
                     /translation="MSKTHLTEQKFSDFALHPKVVEALEKKGFHNCTPIQALALPLTL
                     AGRDVAGQAQTGTGKTMAFLTSTFHYLLSHPAIADRKVNQPRALIMAPTRELAVQIHA
                     DAEPLAQATGLKLGLAYGGDGYDKQLKVLESGVDILIGTTGRLIDYAKQNHINLGAIQ
                     VVVLDEADRMYDLGFIKDIRWLFRRMPPANQRLNMLFSATLSYRVRELAFEQMNNAEY
                     IEVEPEQKTGHRIKEELFYPSNEEKMRLLQTLIEEEWPDRAIIFANTKHRCEEIWGHL
                     AADGHRVGLLTGDVAQKKRLRILDEFTRGDLDILVATDVAARGLHIPAVTHVFNYDLP
                     DDCEDYVHRIGRTGRAGASGHSISLACEEYALNLPAIETYIGHSIPVSKYNPDALMTD
                     LPKPLRLTRPRTGNGPRRTGAPRNRRRSG"
     gene            40583..42067
                     /gene="gppA"
                     /locus_tag="IRB70_001384"
     CDS             40583..42067
                     /gene="gppA"
                     /locus_tag="IRB70_001384"
                     /EC_number="3.6.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanosine-5'-triphosphate,3'-diphosphate
                     diphosphatase"
                     /protein_id="HBC0631319.1"
                     /translation="MGSTSSLYAAIDLGSNSFHMLVVREVAGSIQTLTRIKRKVRLAA
                     GLNSENALSNEAMERGWQCLRLFAERLQDIPPSQIRVVATATLRLAVNAGDFIAKAQE
                     ILGCPVQVISGEEEARLIYQGVAHTTGGADQRLVVDIGGASTELVTGTGAQTTSLFSL
                     SMGCVTWLERYFADRNLGQENFDAAEKAARKVLRPVADELRYHGWKVCVGASGTVQAL
                     QEIMMAQGMDERITLEKLQQLKQRAIHCGRLEELEIDGLTLERALVFPSGLAILIAIF
                     TELNIQCMTLAGGALREGLVYGMLHLTVEQDIRSRTLRNIQRRFMIDIDQAQRVAKVA
                     ANFFDQVENEWHLEAISRDLLISACQLHEIGLSVDFKQAPQHAAYLVRNLDLPGFTPA
                     QKKLLATLLLNQTNPVDLSSLHQQNAVPPRVAEQLCRLLRLAIIFASRRRDDLVPEMT
                     LQANHELLTLTLPQGWLTQHPLGKEIIDQESQWQSYVHWPLEVH"
     gene            complement(42114..44135)
                     /gene="rep"
                     /locus_tag="IRB70_001385"
     CDS             complement(42114..44135)
                     /gene="rep"
                     /locus_tag="IRB70_001385"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase Rep"
                     /protein_id="HBC0631320.1"
                     /translation="MRLNPGQQQAVEFVTGPCLVLAGAGSGKTRVITNKIAHLIRGCG
                     YQARHIAAVTFTNKAAREMKERVGQTLGRKEARGLMISTFHTLGLDIIKREYAALGMK
                     ANFSLFDDTDQLALLKELTEGLIEDDKVLLQQLISTISNWKNDLKTPSQAAASAIGER
                     DRIFAHCYGLYDAHLKACNVLDFDDLILLPTLLLQRNEEVRERWQNKIRYLLVDEYQD
                     TNTSQYELVKLLVGSRARFTVVGDDDQSIYSWRGARPQNLVLLSQDFPALKVIKLEQN
                     YRSSGRILKAANILIANNPHVFEKRLFSELGYGTELKVLSANNEEHEAERVTGELIAH
                     HFVNKTQYKDYAILYRGNHQSRVFEKFLMQNRIPYKISGGTSFFSRPEIKDLLAYLRV
                     LTNPDDDSAFLRIVNTPKREIGPATLKKLGEWAMTRNKSMFTASFDMGLSQTLSGRGY
                     EALTRFTHWLAEIQRLAEREPIAAVRDLIHGMDYESWLYETSPSPKAAEMRMKNVNQL
                     FSWMTEMLEGSELDEPMTLTQVVTRFTLRDMMERGESEEELDQVQLMTLHASKGLEFP
                     YVYMVGMEEGFLPHQSSIDEDNIDEERRLAYVGITRAQKELTFTLCKERRQYGELVRP
                     EPSRFLLELPQDDLIWEQERKVVSAEERMQKGQSHLANLKAMMAAKRGK"
     gene            44222..44503
                     /gene="ppiC"
                     /locus_tag="IRB70_001386"
     CDS             44222..44503
                     /gene="ppiC"
                     /locus_tag="IRB70_001386"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004097481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase PpiC"
                     /protein_id="HBC0631321.1"
                     /translation="MAKTAAALHILVKEEKLALDLLEQIKNGADFGKLAKKHSICPSG
                     KRGGDLGEFRQGQMVPAFDKVVFSCPVLEPIGPLHTQFGYHIIKVLYRN"
     gene            complement(44549..46024)
                     /gene="ilvC"
                     /locus_tag="IRB70_001387"
     CDS             complement(44549..46024)
                     /gene="ilvC"
                     /locus_tag="IRB70_001387"
                     /EC_number="1.1.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketol-acid reductoisomerase"
                     /protein_id="HBC0631322.1"
                     /translation="MANYFNTLNLRQQLAQLGKCRFMGRDEFADGASYLQGKKVVIVG
                     CGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENGFKVGTYEELIPQADLV
                     VNLTPDKQHSDVVRTVQPLMKDGAALGYSHGFNIVEVGEQIRKDITVVMVAPKCPGTE
                     VREEYKRGFGVPTLIAVHPENDPKGEGMAIAKAWAAATGGHRAGVLESSFVAEVKSDL
                     MGEQTILCGMLQAGSLLCFDKLVEEGTDPAYAEKLIQFGWETITEALKQGGITLMMDR
                     LSNPAKLRAYALSEQLKEIMAPLFQKHMDDIISGEFSSGMMADWANDDKKLLTWREET
                     GKTAFETAPQYEGKIGEQEYFDKGVLMIAMVKAGVELAFETMVDSGIIEESAYYESLH
                     ELPLIANTIARKRLYEMNVVISDTAEYGNYLFSYACVPLLKPFMAELQPGDLGKAIPE
                     GAVDNAQLRDVNEAIRSHAIEQVGKKLRGYMTDMKRIAVAG"
     gene            46174..47064
                     /gene="ilvY"
                     /locus_tag="IRB70_001388"
     CDS             46174..47064
                     /gene="ilvY"
                     /locus_tag="IRB70_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator IlvY"
                     /protein_id="HBC0631323.1"
                     /translation="MDLRDLKTFLHLAESRHFGRSARAMHVSPSTLSRQIQRLEEDLG
                     QPLFIRDNRTVTLTEAGEELRVFAQQTLLQYQQLRHTIDQQGPSLSGELHIFCSVTAA
                     YSHLPPILDRFRAEHPSVEIKLTTGDAADAMEKVVTGEADLAIAGKPETLPGAVAFSM
                     LENLAVVLIAPTLPCPVRNQVSVEKPDWSTVPFIMADQGPVRRRIELWFRRNKISNPM
                     IYATVGGHEAMVSMVALGCGVALLPEVVLENSPEPVRNRVMILERSDEKTPFELGVCV
                     QKKRLHEPLIEAFWKILPNH"
     gene            complement(47061..48605)
                     /gene="ilvA"
                     /locus_tag="IRB70_001389"
     CDS             complement(47061..48605)
                     /gene="ilvA"
                     /locus_tag="IRB70_001389"
                     /EC_number="4.3.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine ammonia-lyase, biosynthetic"
                     /protein_id="HBC0631324.1"
                     /translation="MADSQPLSGAPEGAEYLRAVLRAPVYEAAQVTPLQKMEKLSSRL
                     DNVILVKREDRQPVHSFKLRGAYAMMAGLTEEQKAHGVITASAGNHAQGVAFSSARLG
                     VKALIVMPTATADIKVDAVRGFGGEVLLHGANFDEAKAKAIELSQQQGFTWVPPFDHP
                     MVIAGQGTLALELLQQDAHLDRVFVPVGGGGLAAGVAVLIKQLMPQIKVIAVEAEDSA
                     CLKAALDAGHPVDLPRVGLFAEGVAVKRIGDETFRLCQEYLDDIITVDSDAICAAMKD
                     LFEDVRAVAEPSGALALAGMKKYIAQHNIRGERLAHILSGANVNFHGLRYVSERCELG
                     EQREALLAVTIPEEKGSFLKFCQLLGGRSVTEFNYRFADAKNACIFVGVRLSRGLEER
                     KEILQMLNDGGYSVVDLSDDEMAKLHVRYMVGGRPSHPLQERLYSFEFPESPGALLRF
                     LNTLGTHWNISLFHYRSHGTDYGRVLAAFELGDHEPDFETRLNELGYDCHDETNNPAF
                     RFFLAG"
     gene            complement(48608..50458)
                     /gene="ilvD"
                     /locus_tag="IRB70_001390"
     CDS             complement(48608..50458)
                     /gene="ilvD"
                     /locus_tag="IRB70_001390"
                     /EC_number="4.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxy-acid dehydratase"
                     /protein_id="HBC0631325.1"
                     /translation="MPKYRSATTTHGRNMAGARALWRATGMTDADFGKPIIAVVNSFT
                     QFVPGHVHLRDLGKLVAEQIEAAGGVAKEFNTIAVDDGIAMGHGGMLYSLPSRELIAD
                     SVEYMVNAHCADAMVCISNCDKITPGMLMASLRLNIPVIFVSGGPMEAGKTKLSDQII
                     KLDLVDAMIQGADPKVSDSQSDQVERSACPTCGSCSGMFTANSMNCLTEALGLSQPGN
                     GSLLATHADRKQLFLNAGKRIVELTKRYYEQNDESALPRNIASKAAFENAMTLDIAMG
                     GSTNTVLHLLAAAQEAEIDFTMSDIDKLSRKVPQLCKVAPSTQKYHMEDVHRAGGVIG
                     ILGELDRAGLLNRDVKNVLGLTLPQTLEQYDVMLTQDDAVKNMFRAGPAGIRTTQAFS
                     QDCRWDSLDDDRANGCIRSLEHAYSKDGGLAVLYGNFAENGCIVKTAGVDDSILKFTG
                     PAKVYESQDDAVEAILGGKVVAGDVVVIRYEGPKGGPGMQEMLYPTSFLKSMGLGKAC
                     ALITDGRFSGGTSGLSIGHVSPEAASGGSIGLIEDGDLIAIDIPNRGIQLQVSDAELA
                     ARREAQEARGDKAWTPKNRERQVSFALRAYASLATSADKGAVRDKSKLGG"
     gene            complement(50523..51452)
                     /gene="ilvE"
                     /locus_tag="IRB70_001391"
     CDS             complement(50523..51452)
                     /gene="ilvE"
                     /locus_tag="IRB70_001391"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain-amino-acid transaminase"
                     /protein_id="HBC0631326.1"
                     /translation="MTTKKADYIWFNGEMVRWEDAKVHVMSHALHYGTSVFEGIRCYD
                     SHKGPVVFRHREHMQRLHDSAKIYRFPVSQSIDELMEACRDVIRKNNLTSAYIRPLIF
                     VGDVGMGVNPPAGYSTDVIIAAFPWGAYLGAEALEQGIDAMVSSWNRAAPNTIPTAAK
                     AGGNYLSSLLVGSEARRHGYQEGIALDVNGYISEGAGENLFEVKDGVLFTPPFTSSAL
                     PGITRDAIIKLAKELGIEVREQVLSRESLYLADEVFMSGTAAEITPVRSVDGIQVGEG
                     RCGPVTKRIQQAFFGLFTGETEDKWGWLDQVNQ"
     gene            complement(51472..51735)
                     /gene="ilvM"
                     /locus_tag="IRB70_001392"
     CDS             complement(51472..51735)
                     /gene="ilvM"
                     /locus_tag="IRB70_001392"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 small subunit"
                     /protein_id="HBC0631327.1"
                     /translation="MMQHQVNVSARFNPETLERVLRVVRHRGFHVCSMNMAAASDAQN
                     INIELTVASPRSVDLLFSQLNKLVDVAHVAICQSTTTSQQIRA"
     gene            complement(51732..53378)
                     /locus_tag="IRB70_001393"
     CDS             complement(51732..53378)
                     /locus_tag="IRB70_001393"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001012636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase 2 catalytic subunit"
                     /protein_id="HBC0631328.1"
                     /translation="MNGAQWVVHALRAQGVNTVFGYPGGAIMPVYDALYDGGMEHLLC
                     RHEQGAAMAAIGYARATGKTGVCIATSGPGATNLITGLADALLDSIPVVAITGQVSAP
                     FIGTDAFQEVDILGLSLACTKHSFLVQSLEELPRIMAEAFDVASSGRPGPVLVDIPKD
                     IQLASGDLEPWFTTVENEVTFPHAEVEQARQMLAKAQKPMLYVGGGVGMAQAVSALRE
                     FLATTKMPATCTLKGLGAVEADYPYYLGMLGMHGTKAANFAVQECDLLIAVGARFDDR
                     VTGKLNTFAPHASVIHMDIDPAEMNKLRQAHAALQGDLNALLPALQQPLNIDDWQQHC
                     AQLRDEHAWRYDHPGDAIYAPLLLKQLSDRKPADCVVTTDVGQHQMWAAQHIVHTRPE
                     NFITSSGLGTMGFGLPAAVGAQVARPNDTVVCISGDGSFMMNVQELGTVKRKQLPLKI
                     VLLDNQRLGMVRQWQQLFFQERYSETTLTDNPDFLMLASAFGIPGQHITHKDQVEAAL
                     DTMLNSDGPYLLHVSIDELENVWPLVPPGASNSEMLEKLS"
     gene            complement(53381..53431)
                     /locus_tag="IRB70_001394"
     CDS             complement(53381..53431)
                     /locus_tag="IRB70_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631329.1"
                     /translation="MNNSTKFCFSRFRTGN"
     gene            complement(53518..53616)
                     /gene="ilvL"
                     /locus_tag="IRB70_001395"
     CDS             complement(53518..53616)
                     /gene="ilvL"
                     /locus_tag="IRB70_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilv operon leader peptide"
                     /protein_id="HBC0631330.1"
                     /translation="MTALLRVISLVVISVVVIIIPPCGAALGRGKA"
     gene            53969..55488
                     /locus_tag="IRB70_001396"
                     /pseudo
     CDS             53969..55488
                     /locus_tag="IRB70_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312727.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YifB family Mg chelatase-like AAA ATPase"
     gene            complement(55513..55851)
                     /gene="maoP"
                     /locus_tag="IRB70_001397"
     CDS             complement(55513..55851)
                     /gene="maoP"
                     /locus_tag="IRB70_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrodomain Ori organization protein MaoP"
                     /protein_id="HBC0631331.1"
                     /translation="MAESFTTTNRYFDNKHYPRGFSRHGDFTIKEAQLLERHGYAFNE
                     LDLGKREPVTEEEKLFVAVCRGEREPVTEAERVWSKYMTRIKRPKRFHTLSGGKPQVE
                     GAEDYTDSDD"
     gene            55970..56809
                     /gene="hdfR"
                     /locus_tag="IRB70_001398"
     CDS             55970..56809
                     /gene="hdfR"
                     /locus_tag="IRB70_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator HdfR"
                     /protein_id="HBC0631332.1"
                     /translation="MDTELLKTFLEVSRTRHFGRAAESLYLTQSAVSFRIRQLENQLG
                     VNLFTRHRNNIRLTAAGEKLLPYAETLMSTWQAARKEVAHTSRHNEFSIGASASLWEC
                     MLNQWLGRLYQNQDAHTGLQFEARIAQRQSLVKQLHERQLDLLITTEAPKMDEFSSQL
                     LGYFTLALYTSAPSKLKGDLNYLRLEWGPDFQQHEAGLIGADEVPILTTSSAELAQQQ
                     IAMLNGCTWLPVSWARKKGGLHTVVDSTTLSRPLYAIWLQNSDKNALIRDLLKINVLD
                     EVY"
     gene            complement(56904..56979)
                     /locus_tag="IRB70_001399"
     tRNA            complement(56904..56979)
                     /locus_tag="IRB70_001399"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(56944..56946),aa:Trp,seq:cca)
     gene            complement(56988..57064)
                     /locus_tag="IRB70_001400"
     tRNA            complement(56988..57064)
                     /locus_tag="IRB70_001400"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(57028..57030),aa:Asp,seq:gtc)
BASE COUNT        14046 a        15385 c        14477 g        13195 t
ORIGIN      
        1 ataatcaaag aatgtatcga aaatggcatt aattcaactc cctcgacagg ataccaacct
       61 cttatcctgc aaagcattaa aaccaaatta ctttcatcaa gactaaataa atttaatgac
      121 ttcgaggaca gttttaatgg cttaggaatc agtgttcatg atatttcagc tcaaaaaata
      181 tctcttttaa gttttcaaaa atacgctata ggatggagtg caacaattca ttttgtagca
      241 caggaccact tcggtcttga tgtaactgat atcaaaaaca agacttacag caaatataga
      301 ttttttcgca tatggttctt tttacaacgg cataaagact ttgctttcaa accttttttc
      361 accaatttta acactatcga aagaatcgaa aattatctat gaaaagcaaa ctccagaaaa
      421 ttatattata tttatttctt ctatgctgca tctataattt atggacattg cgtcctgtac
      481 agattttgta tacatactct gatgctggca attcagtctt tctggtcgtt gatcatctgc
      541 catggactga cagcgataaa ataaattggt atctgaagca tcagaatgaa attaaaaatc
      601 aacatcccct accagaaggt agttggcata cctggtatgt tattgatatc ggtaatggct
      661 tcactgacta taaaaaatat atcgaagggc cgtatgaaga tctctactgt ttcccgacga
      721 ttaagagcaa tgataattgc atcgtaaaaa actatttaat ggttattaat gaatatcctt
      781 accgtaatac tcattttttt attgctgata acaatgagta tcaactaacc caggaaaata
      841 agatagagcg agtgttcaac ccgcatgact ttgaaaaaga caattttcag caataagccg
      901 gataaagaac aatctttacc cggcatttat attacaacca gttcttccgc ttaaagtaga
      961 gatacggtgc caggcccgcg aggatcataa agataatcgc gcctgggtag ccgaagctcc
     1021 acttcagttc tggcataaac tcaaagttca tcccgtagct ggaagcaacc agcgtcggcg
     1081 gcaggaacac gacggatacc accgagaaga ttttgatgat gcggttctgc tcgatattga
     1141 taaagcccat cgccgcctgc atcaggaagt tcaccttctg gaacagggat tcgttatgcg
     1201 gcagcaggga ttcgatatct cgcaggattt cacgcgcctg ctccagttgc ccacccggta
     1261 aacgcgcctt gcgtaccagg aagttgagcg cacgctgggt atccatcaga cacaggcgaa
     1321 ctttccagcc gatatcttcc agttccgcca gcgtggagag cgcctcgtcg tactcatcgc
     1381 cctgatgccc ttccataatt acccggctca actgctccag gtcactgtag atattttcaa
     1441 tttcatctgc caactgttcg attttagttt cgaacagatc caacagcagc tcgtaggcgt
     1501 taccgtctac catcgactgg ctacgggcac gcatacgata cagacgaaaa gcgggcagtt
     1561 cacgctcacg cagagtaaac agacgaccat cacggatggt aaatgccaca gtggagttac
     1621 cggcgtgatc ttccgcatct tcaaagaaga agaaggagtg aatatgcagg ccgtcatcgt
     1681 cttcaaagaa acgtgccgat gcttcgatgt cttccagttc cgggcgggtt gccaggctct
     1741 gaccaagttc agattgtacg cgcagtcgct cgtcgtcgtc cggttcgaca agatcaatcc
     1801 atactgcatt tacaaggggt tgtgactctt cgacttccag ccgggtcagt cggttatttt
     1861 ccagttgaaa tgcgctcagc atgaccggga ctcccaatgc ttaaaatatc ggacagttcg
     1921 gtgggcacac agaaacaaat tgggtttcag accattaaac agcctgactc agcgcgacgg
     1981 gaaaaattga ggtcgctgac aaccgctaag gctatcagca aaaagggata gccttaggag
     2041 ttgatcctgg atgacaggat agtgagccag tatctactgg gtgtgtccaa ggcgaatgtc
     2101 ctcttagagt gatcgtgcgc gcatgttacg ccagcaaaat tttgccgtca acacgcaaca
     2161 gaacaccaca gaacaatagt tgaacttcgc gctttttggt actcgtcaag gtcgctaaca
     2221 ggataaaaaa atcccacatc caggacctat aatggcgcat cggctactca ttggtaaagg
     2281 aatgatcacc ttgaatctca aacggatttt tctcaccttc accttacttc ccttgtttgc
     2341 tgttgccgct gatgattgcg cactctcaga tccgacgctg accgtacagg cgtataccgt
     2401 taatcctcaa acagagcggg tgaaaatgta ctggcaaaaa gccaatggcg aagcgtgggg
     2461 aacgttacat gctctgctgg cggatatgaa tagtcagggt caggtgcaga tggcgatgaa
     2521 cggcggcatc tatgatgaaa gctatgcgcc gctcggtttg tacatcgaaa acggtcagca
     2581 gaaggtggcg ttaaatctcg cttcaggtga agggaatttc tttattcgtc ctggcggcgt
     2641 gttttatgtc gcgggagata aagtcggcat cgttcgtctg gatgccttta aaaccagtaa
     2701 agagattcag tttgcggtgc agtcagggcc aatgttatta gaaaacggcg taattaatcc
     2761 acgcattcac ccgaatgttg cctcgcgtaa aattcgtaac ggtgtaggga ttaataaaca
     2821 agggaacgcc gtgtttttgt tgagccagca gccgacaaat ttttatgatt ttgcctgtta
     2881 tgccaaagcg aaactgaacg ttgagcagtt gctttatctt gatggcacaa tttcacatat
     2941 gtatatgaaa ggcggggcaa tcccgtggca acgctatcct tttgtcacca tgatttccgt
     3001 cgagcggaaa ggttaagcat tgtacactcg aggaggccag acaaactggg actggctaca
     3061 cagctggaaa atcatcagat aaatgaaggg aaacaaaaat gaaaaaaacg ctcgcaacgt
     3121 tatttttatt aacgtgtctg ggatcatcat ccgcctatgc ggataacgct ttgattttac
     3181 aaacggattt tagcctgaaa gatggtgccg tctcggcgat gaaaggggtc gcattcggcg
     3241 ttgaccataa tcttaaaatc tttgatttaa cacacgaaat tccaccgtat aacatctggg
     3301 aaggcgctta tcgcctgtat cagactgcca gttactggcc gcaaggttcg gtgtttgtta
     3361 gcgtggtcga tccgggcgta ggcactgacc gtaaatcggt agtgctgaaa accaaaaacg
     3421 gtcaatactt cgtttcacca gataacggta cgctcacttt ggtggcacaa actctgggta
     3481 ttgatagcgt ccgggaaatc gacgaaaaag ctaaccgcct gaaaggttct gaaaagtcat
     3541 ataccttcca tggtcgcgat gtatatgcct acaccggtgc gcgtctggct tccggagtga
     3601 tcacgttcga acaggtgggg ccagagcttc ctgcaaaagt tgtcgaactt tcttatcaga
     3661 aagcaaaagc aacaaaaggt gaagtgaagg gcaatatccc aattctcgat attcagtacg
     3721 gcaacgtctg gagcaatatc agcgacgagt tgctgaatca ggcaggaatc aaactcaacg
     3781 acacgttgtg tgtgaccatt tccgaaggtt cccagcaaaa atacgcaggg aaaatgccat
     3841 atgtcgcaag cttcggcgat gtgccggaag gccagccgat ggtgtatctg aacagcttat
     3901 tgaatgtttc cgtggcgctg aatatggata attttgcgca gaaacatcag gttgcgtctg
     3961 gtgctgactg gaatattgat gtgaagaagt gcgctaagta aggtgctgat gccgaatgcg
     4021 gtgtggcgca ccgcatcctg caacggagtt gtaaattaca ccgtctccag tcgggcataa
     4081 gccgccacca gccatttaat accctggccc tggaatgcca cctgcaaacg gctatgctcg
     4141 ccgctgcctt ccatattgac gatggtgcct tcaccaaact tagcgtggcg tacgcgctgg
     4201 ccgagcttgt agccgctgtc gttctcgacc atcggcgtac ccatccgttg atggctgacc
     4261 gggcggctta ccgtagcgcg caggcgcacc tcttccacac actcttccgg caactcaccg
     4321 ataaagcgcg acgggcgatg gtaaacctct ttgccataca gacggcgagt ttccgcgtag
     4381 gtcagcgtca gtttctgcat cgcgcgggtt acgccaacgt aggccagacg gcgttcttct
     4441 tccagacgtc cgccttcatc cagcgacatc tggcttggga acatgccctc ttccatacca
     4501 acgataaaca cctgcgggaa ctccaggcct ttcgccgagt gtagcgtcat caactgcacc
     4561 gcgtcctgcc aggtatccgc ctgcccctcg cccgcttcca gcgccgcatg ggagaggaat
     4621 gcctgcagcg gcattaaatc ttcgtcttct tcgttgtagc tgaactggcg cgttgccgtc
     4681 accagttcct ccaggttttc gatacgcgtc tgaccttttt cgcccttctc ctgctcgtac
     4741 atggtgcgca agccggagtc tttaattacc cggtcagtct gtacatgcag cggcatatcg
     4801 gcagtttcct gcgctaaggc gtcgatcagt tccataaacc gctgtaaggc actggcagca
     4861 cgtccggcga gggctttttc ctgcaacagt tcacgacatg cctgccagag tgttaactgg
     4921 cgatcacgcg atgtctgacg taccacgtcc agcgtccggt caccaatacc ccgcgttggc
     4981 gtattaacca cacgctcaaa ggccgcgtcg tcgttgcggt tggcaatcag gcgcagatac
     5041 gagagcgcgt ctttgatttc ctggcgttcg aagaagcgca tcccgccgta aatacggtac
     5101 ggcatacttg cctgtaacag tgcttcttcc agcacacgcg actgggcgtt gctgcggtag
     5161 agaatggcgc actcggcaag cgccccgccg ttgtcctgcc aggttttgat acggttaacc
     5221 acaaaacgcg cttcatcgag ttcgttaaaa gcgcaataga gggaaatagg ctcaccatcc
     5281 gcgccatcgg tccacagttt tttacccaaa cgcccgttgt tgttttcaat cagagcgttc
     5341 gcggcgctca gaatattgct ggtagagcgg tagttctgct ccagacggat agtttcagca
     5401 ccggggaaat cattgaggaa acgctgaata ttctccacct gcgctccgcg ccagccgtag
     5461 attgactgat cgtcatcgcc aacgatcatc actttgccgg tatcgcccgc cagcaggcgg
     5521 atccacgcat actgaatgtt gttggtatcc tggaattcgt ccaccaggat attggtaaac
     5581 cgttcgcgat agtgctgaag gatatgcggt ttgttaagcc acaactcgtg agcacgtagc
     5641 agcagctcgg cgaagtccac caggcccgcg cggtcacacg cttcctgata cgcctgatac
     5701 accttctgcc aggtctgctc caccggatta ccgtagcttt gaatatgatg tggacgcagg
     5761 ccttcatctt tctggctgtt gatgtaccac attgcctggc gcggcggcca ctgcttctcg
     5821 tcgaggttca tcgccttgat taggcgtttg agcaggcgta gctggtcctc gctgtcgagg
     5881 atctgaaaat cctgcggcag attggcgtcc atatggtgcg cacgcagcag acggtgcgcc
     5941 agcccgtgga aggtgccgac ccacatgccg ccctggctgg tgcccatcag ctgcccgata
     6001 cgatgacgca tctccgccgc cgctttgttg gtaaacgtta ccgccataat cgagtatggc
     6061 gagcagtttt ccacgctcat cagccaggcg atacgatgca ccagtacgcg cgtcttacca
     6121 ctgcccgcgc ccgccagcac cagaaggttg ctgcgtggcg cggctaccgc ttcgcgctgt
     6181 ttgtcattaa ggctgtcgag caggtaagaa acgtccattg gcaccgccgc gtaaaaatag
     6241 gttgggcgga gaagcgcaac gccctccgcc aaaaagctgg gtatatatac agatttgctg
     6301 attatatcag cgaggtcaga gatgccaacc gggaaatttc cagatgcggg agtaaacggc
     6361 tgtcccaggt ttgcatcaga tcgccatttt ccggtctgat ccaacaggcc tgcattccgc
     6421 tgcgaattgc cccacccacg tcagtggtga gatcgtcccc gacatgtaag atctcgccga
     6481 tcggcacgtt gagtttttcc gccgccagga agtacatatc gctgaacggt tttgagcgcc
     6541 cgtgcgggcc agcgcgcaac acaaactcaa aataatcccc taaaccaaac agctccggct
     6601 gggcgttacc gttggtgatc gccaccagcg gccatttctt cgccagctgt tttaaggtgt
     6661 cgtgggtttg ctgcgggaca tcgattcggc tgcgccattt ggcaaagttg atcattgctg
     6721 cgtgtgcgcc tgcactggct tcttcggcac tcagcccggc gtcgagcatg gcttgttcaa
     6781 tcgaacgaaa acgccagcgc gtcacgtcgt gataaatctc gggttccgct tcccgtaccg
     6841 cctggcgcag gcgttgcaga tcttcattct ggaagctgcg cagcgccgga tgataatttt
     6901 gcacaaaggt aagcgcctct cgctcggtgc gcaaaatcac cggacggtta tcgtaaaggg
     6961 tatcatccag gtcaaaggtg agcgccgaga tgcgccccaa aggccggtaa aaacgcatta
     7021 tttcccccgt ttggcgcgtg gatgcgccgc atcgtacacc gaggcaaggt gttgaaaatc
     7081 aagatgagta tagatttgcg tggtggagag gttggcatga cccagcagct cctgcacacc
     7141 acgaagatcg ccgctcgact ccagcatatg cgtagcgaac gagtgacgta atttatgcgg
     7201 gtgaacgtga ttattcagcc cttgtttgat gccccattcg gcaaagcgtt tctgcacatt
     7261 acgcgcggag atacgcttgc ccagtttcga cagaaaaagc gcgtcgtctt cgctcccaaa
     7321 caggtcgcgc aaatcaagcc agtgctcaat ccacgccaca gcgttgcgac caatcggcag
     7381 gcggcgctct ttgctgcctt ttcccataac ccacacttca ccagactcca ggtcgaggtg
     7441 tttgatatcc agccccacca gctcggaaag acgcagaccc gcgccgtaca tcacttccag
     7501 cattgcccga tcgcgcacgg cgaggggatc gttgatatca atatccagca gccgattcat
     7561 atcatcgacg tcgatgtttt tcggcagatg acgcggcgct ttcggtgccg aaacaccttt
     7621 cgccgggttg gctttgagtt cgttctggct gaccagccaa tcaaaaaagc tacgtagcgc
     7681 agaaagccgt aacgccagac ttgcagctcc cagcccttta cggcgactgc gtacagcgaa
     7741 attgcgcacc atcgtcacat cacattgctg ccagctttgc aggccgtttt cactggcaaa
     7801 attgatgatc gcctcaagct gacgctgata gttaagcagg gttatcgggc taagctgacg
     7861 ctccacgctc agataacgta ggtagcgttc tacatcggtg tgtaaatcgg tcatacgcgt
     7921 tcaatccaac gctccagaag ctccggcaac atcagcgcaa tttcatgaag taactgcgtt
     7981 ccctgccctt gttgatagtg actggcatcg cgactggtaa acaacacaac acccaaatca
     8041 gcatcgcttc ccagcatcga catcgccacc gatcccaccg ctttcgcttc cggtagcacc
     8101 accagaagct ccggtccgtt aagcggtccc agatagtgct gttcctgccc cagacgctga
     8161 atacgcagcg gttcgaaaga ctgacggctt aatgccagat gagtgtggtt cgacggcgca
     8221 cctaaacgcc agcgatccgg gaacaggcgc aggctcgcac ccgccaggcc gagatcgcgc
     8281 gcccagcggt gaaagcgcat cagcatatcg tcgagactgc tggcggcggt gagactacgc
     8341 tgcaagtaga gtaagcgata aaacaggcct tcgttggcga tagcctgttc catcaacagc
     8401 gccatgttct cttccagaac atgaatgtga ttacgtgcgc gggccatgtg ccactcgacc
     8461 aacgaaacgg tgccgcgtac cggatgcggc acacgtatcg cttctactgc gcgcgcattg
     8521 cggataaaaa actcaggatt tttaatcaga taatcgacaa ccgcccggtc atcaagctcc
     8581 gtgagtgttt cctgcagttc ttcccctggt tgcttcatag atgaataaat ccgtcgtaga
     8641 catgtaccgc cgggccagtc atatataacg ggtgacccgg acctttccag gcgatatcaa
     8701 gacgaccgcc ggggagttcc acgcgtactt cttcggccag caaaccttgc tgaatcccta
     8761 ccgccaccgc cgcacacgcg ccgctgccgc aggcctgggt ttctcctgcc ccacgctcat
     8821 aaacgcgtaa acgaatatgc tcgcgcttaa ccacttgcat aaaaccgata ttggcgcgct
     8881 ccgggaaacg ttcgtggctt tccagaacag gaccaagcgt ttctaccgcc gcggtatcga
     8941 catcatcgac ctgaatcacg cagtgcggat ttcccatcga caccacgcca cataagattg
     9001 tctgctcggc ggcgcgcata atataggtct tttccgcttt gttagcgcga aatggcacgg
     9061 cagaaggttc gaagttgggt tcgcccatat tgacgcggac cagatcatca tcggtgacgg
     9121 tcaacaccat ccgtccgttg gcggtgctga cgcggatatc gcgcttattg gtcagccctt
     9181 tcagacgcac aaaacgggca aagcagcgtg ctccgttgcc gcactgcgcc acttcactgc
     9241 catcagcatt gaaaatgcga tagtgaaaat ccagttcagg atcatacggc ggctcaacca
     9301 ccagcagctg gtcaaaccct acccccaggt gccgatcagc caggcgacga atcagctccg
     9361 gtgaaaaaaa gacattctgc gttaccgcgt cgacgaccat aaaatcgttg ccaaggccat
     9421 gcattttcga gaactgcatc atttactcca atcacgcggg tacagaaact gacttttagt
     9481 aattcacctg ggatggacca tcgccagtgg cgcgatcgtt tttatccggc accgtggatt
     9541 gcgtttgcgt ctctaccggt ttggtcggcg gcggtgcgtt tttatctgca ggcgggaaat
     9601 agagcggacc tttcagaccg cagcccgtca ggctgaagag agtaagtaat acagtgagtg
     9661 ccttaaacac gtttttcatt atggattgcc tgtaaagttc atcgctttct gctttctatc
     9721 atcgcaggag aaggcgtaaa agcaagcgtt tagcgactct ttatgaagtc tgaaaagtga
     9781 ggaaatgctg cgagtataac gcttacacgt ggcgatttat gttttgctgg tagtttcgtg
     9841 atcggcacct cgcgccagga tggctttatg cactatcgca atgtggtttg tttgttgtct
     9901 tgttcgttgt ttttatcatc ggcatgggga tgtcggcttg atgagccgga acataatatt
     9961 taccagaaac agggaaaagg cgtggtgtac ctgcgccctt atgaaaagac caatctttcg
    10021 ctatatagag atattattat tccgttgacg gatgaatcat gccgtaacgc agccgcagac
    10081 gggcaaactt tgaagccctg accccatacc gctatactgc cgccatcact taaaaacagg
    10141 atacaacaat gaacgacagt gaatttcatc gcctggctga tcaactgtgg ctgaccattg
    10201 aagagcgtct ggacgactgg gatggcgata gcgatatcga ctgcgaaatc aacggcggtg
    10261 tgctgaccat tacctttgaa aacgggagca aaatcattat caaccgccag gaaccgctgc
    10321 accaggtatg gctggcaacc aaacagggcg gctaccattt tgatatgaaa ggcgatgagt
    10381 ggatttgcga tcgtagcggc gaaaccttct gggatttgct ggaacaggcg gcaacgcagc
    10441 aagcgggtga aacagtcagt ttccgctaag attgcatgcc ggataagcct cgctttccgg
    10501 cacgctcatc acgaaaaata ctgctgtaat agcggcgtgt cgtgatcctg attggcaggc
    10561 ggcatgttgc caatcgattt ggtgcggaac ggaatcacct gttcacgacc atcaaccttc
    10621 acaatctgat agaactgcgg caggttgaag ttgatgaagc ttgagccgta ggtaaaacgg
    10681 tcgtgcgatg acgagtagaa gcgactgacg tcacgcacca gctcctcttt gctgccttcg
    10741 cagtggtgat acacctcaac ccggttgctt tcgtcgagaa tgtagatatt aaagccattc
    10801 tcgtcttgcg tttcttcgaa gaagaactgg atgatccctt cgctggcaaa gccgtccacc
    10861 accgccggta atttgacgtg attggtttca acctgcactg acaggccgtg cagtttgtta
    10921 tgcgaaatag cgccataaaa ctcgatggca ttttccagtt tctgtaccga tacattcagg
    10981 cgttcgaaga ataagcccca ggtttgacca gaaacgcgca gcgccttgaa gcgcccagtt
    11041 tcctggcggg tgctggaaag acgcagttca atgcactcag aaaccagttg ctgcacgcga
    11101 gtacggatta atccgcgcag atgctggctg tagcagaaga cttccacgct atctggcggt
    11161 gcggcgtcct gatgcatttt accgagaatg gttttcaggg cttcgatcat cgactgctcg
    11221 ccgttgaagt gcaacgtacg cacttcgttc cacgagttgc ggtacagcag gtccacgcta
    11281 cctaccaggc aattttgatt ctcgccaaag ctgaagacgt ccagcttacg gaaatcaaaa
    11341 tgcaccacct gattgcggaa cgcagctgtc gggtcatatt ccaggttaac gataatcgcc
    11401 agatggcgga tctcacacgg gctgtagagc gcttttggcg tcggtgcagg caggcgcaac
    11461 gggaaatggt gcgacacgtc ggcgaccatc tcctgcaact taggcaaatc gacaatgccg
    11521 ttacctttaa tatacaaacg ggtgcgcgag gtcagcaggc cgttaaacca tgcccacgcc
    11581 accagtttat tcaggtaacg gttatattcc agcggctgat ggctgatgat tgactcaata
    11641 tttggcgcgc ggttatacag ataccaacct gaacggttgg cgcggcccgg cggtacataa
    11701 ataaaggtca gattcggttc cgagagatcg ggcgaaatct gcgggtttac cagcgtcact
    11761 ttacctggca atgcttcaaa cgcggcatac agtttacgcg tcagtacgcc gatatcctgc
    11821 ggactggcgg agacgctaag gttattgcga cgcgcaaagc ggatcagatt acggtagctc
    11881 tgcatcatcg cgtcgagcag ctcgttgtgc gcctcacgca cctgatcaat cttccagttg
    11941 gcgcggttat cgagcattgc cagacgcgca tcgtcccatt cccactcttt cactaactgg
    12001 gttagcactt cacgacgcca gcctacgcaa gcgcgttcgc ggctgagttt ttcgcacact
    12061 tttaaataga agcagcggcg tactaaatcc agacgggtga aatcttcaat cgccgtcagg
    12121 tactcagtaa cacgctccag catcatgcag tatggatcga ggccaaacga cacaatctcg
    12181 ccgtcgtgca aacgctgttt gatatctttc gccagcaggc gtgggttggg atattcccag
    12241 gaataggctt ccaatagcag tgttttcagc accgctttgt atggggaatc gatactcttg
    12301 tagagctgcc aaaggctggc accaaagtac tcttcagcag aaagcgagct taagccaccg
    12361 agatccagcc attcatttgg cgtcagcacg ccctgcgcgt aaagcgtcat cacatagtcg
    12421 tcgtaatgct cttcttcgtc gcacggcacc atattccaca gaatacgctt accggcgaga
    12481 cgcacggcgg tacgataaaa ttcgtcaagc agcagtatat gctgggtgga gccacaatct
    12541 tcgcccccca ggctgccgct ttcattatga cggaaacggt tttcatcaat caggaagaag
    12601 ctgacttcca cacccagcga ggcggcccag ctttccagca ggctgcattt acgttgtagt
    12661 aactggcgct cttcgctatc gagccaggat tgatgacaga cccagatatc caggtcagag
    12721 gaacaacttt gccctacgga cgaggtgctg cccatggtgt atacaccagt aattggaagc
    12781 tcacctttcg gtgggtcctg tactgacatt ccacgataca gttcaagctc gttcaggtag
    12841 tggcgttgag tttcatcagg cgtgtaaagg caaatgcctt tgggaacgtt accatcaagg
    12901 taacccggca ttagcggatg gtgatagtgc aacaatgtcg gcagtagact gtagacctgt
    12961 tggaatgcag gccccatagc agcaagcgcg cgatccacac gcaattgatt tatggcatcc
    13021 agtctctgtt tcagagtctc aatatagagg tacaagacgt atcgcctgat ttgctacccg
    13081 tcatgactgt gattccgcca acatcaacgg taacacgcgg cattcgggat atttcgtatg
    13141 tcaaaggtaa ccgttaccac ttttcgcgcc tggttttttt agtttcacga cgaaaaaatg
    13201 gtctaaaacg tgatcaattt aacaccttgc tgattgaccg taaagaaaga tgcgctacat
    13261 acaagtgtag caccgtttat tctctgtaaa ttccttatta cgacggcgtg aaacgcctgt
    13321 caggatccac tgccagacct cattttacgg tttgcgcagg cgtctacgtt tcaccacaac
    13381 actgacatcg ctctggcaag gatgttagga tggaccacgg atgataatga cggtaacaag
    13441 catgttagac aatgttttaa gaattgccac acgccaaagc ccacttgcac tctggcaggc
    13501 acactatgtc aaagacaagt tgatggcgag ccatccgggc ctggtcgttg aactggtacc
    13561 gatggtgacg cgcggcgatg tgattcttga tacgccgctg gcgaaagtag gcggaaaagg
    13621 cttatttgtt aaagagctgg aagtcgcgct cctggagaat cgcgccgata tcgccgtaca
    13681 ttcaatgaaa gatgtgccgg ttgaattccc gcaaggtctg gggctggtca ccatttgcga
    13741 gcgtgaagat cctcgcgatg cctttgtgtc caataactat gaaagtctgg atgcgttacc
    13801 ggcaggcagt atcgtcggga cgtccagttt acgtcgccag tgccaactgg ctgaacgccg
    13861 cccggatctg attatccgct ccctgcgcgg caacgtcggc actcgcctga gtaaactgga
    13921 taacggcgaa tacgatgcca tcattcttgc cgtagccgga ctaaaacgtt taggtctgga
    13981 gtcacgtatt cgcgccgcgt taccacccga gatttctctt ccggcggtag gacaaggtgc
    14041 ggtcggtatt gaatgccgcc ttgatgatac acgcactcgc gagctgcttg ccgcgctgaa
    14101 tcaccacgaa actgcactgc gcgttaccgc agaacgcgcc atgaataccc gtctcgaagg
    14161 cggatgtcag gtgccaattg gtagctacgc cgagcttatt gatggtgaaa tctggctgcg
    14221 tgcgctggtc ggcgcgccgg acggttcgca gattattcgc ggtgaacgcc gcggtgcgcc
    14281 gcaagatgcc gaacaaatgg ggatttcgct ggcagaagag ctactgaata acggcgcgcg
    14341 cgagatcctc gctgaagtct ataacggaga cgccccggca tgagtatcct tgtcacccgc
    14401 ccgtctcccg ctggagaaga gttagtgagc cgtctgcgca cactggggca ggtggcctgg
    14461 cattttccac tgattgagtt ttctccgggt cgacaattac cacaacttgc tgatcaactg
    14521 gcggcgctgg gggagagcga tctgttgttt gccctctcgc aacacgcggt tgcttttgcc
    14581 caatcacagc tgcatcagca agatcgtaaa tggccccgac tacctgatta tttcgccatt
    14641 ggacgcacca ccgcactggc actacatacc gtaagcggac agaagattct ctacccgcag
    14701 gatcgggaaa tcagcgaagt cttgctacaa ttacctgaat tacaaaatat tgcgggcaaa
    14761 cgtgcgctga tattacgtgg caatggcggt cgtgagctaa ttggggatac cctgacggcg
    14821 cgcggtgctg aggtcacttt ttgtgaatgt tatcaacgat gcgcaatcca ttacgatggt
    14881 gcagaagaag cgatgcgctg gcaatcccgc gaggtgacga cggtcgttgt taccagcggt
    14941 gaaatgttgc agcaactctg gtcgctgatc ccacaatggt atcgtgagca ctggttacta
    15001 cactgtcgac tattggtcgt cagtgagcgt ttggcgaaac tcgcccggga actgggctgg
    15061 caagacatta aggtcgccga taacgctgac aacgatgcgc ttttacgggc attacaataa
    15121 ctctcataac aggaagccat aatgacggaa caagaaaaaa cctccgccgt ggttgaagag
    15181 accagggagg ccgtggacac cacgtcacaa cctgtcgcaa cagaaaaaaa gagtaagaac
    15241 aataccgcat tgattctcag cgcggtggct atcgctattg ctctggcggc gggcgtcggt
    15301 ttgtatggct ggggtaaaca acaggccgtc aatcagactg ccaccagcga tgccctggct
    15361 aatcagctga cggcactgca aaaagcccag gagagccaaa aagctgagct ggaaggcatt
    15421 atcaagcaac aagctgtaca gcttgagcag gcgaatcgtc agcaagaaac gctggcaaaa
    15481 cagctggatg aagtccaaca aaaggtcgcg actatttccg gcagcgatgc taaaacctgg
    15541 ctgctggctc aggctgattt cctggtgaaa ctcgccggac ggaagctgtg gagcgatcag
    15601 gacgtcacga ccgctgcagc gttgctgaaa agtgcagacg ccagcctggc ggatatgaat
    15661 gacccgagtc tgattaccgt tcgccgggca attaccgatg atatcgccag cctttctgcg
    15721 gtatcgcagg tggattatga cggcattatc cttaagctta atcagctttc aaatcaggta
    15781 gataacctgc gtctggctga taatgacagc gatggttcgc cgatggattc cgacggtgaa
    15841 gagctttcca gttccatcag cgaatggcgt atcaatctgc aaaaaagctg gcagaacttt
    15901 atggacaact tcattacgat tcgccgtcgt gatgacaccg ccgtaccgct gttagcgcca
    15961 aatcaggata tctatctgcg cgaaaatatt cgctctcgcc tgctggtcgc tgcacaagct
    16021 gtaccgcgtc atcaggaaga gacttatcgc caggcgctgg agaatgtctc cacttgggta
    16081 cgtgcttact acgatactga tgatgccacc accaaagcgt tcctcgacga ggtggaccag
    16141 ttaagccagc aaaatatctc gatggatctc ccggaaaccc tgcaaagcca ggcgatgctg
    16201 gaaaaattga tgcagacccg cgtgcgtaac ctgctggcac aaccggcagc agggacaacg
    16261 gaagctaaac ctgcacctgc acctgcacct gcacctgcac ctgcacctgc acctgcacct
    16321 gcaccgcaag ctgatactcc ggcagccgcg ccgcaaggag aataaccatg ctaaaagtgt
    16381 tattgctctt tgttttgctg attgcgggga tcgtggttgg cccgatgatt gccggtcatc
    16441 aggggtacgt attgattcag accgacaact acaatatcga aaccagcgtc actggcctgg
    16501 cgattatttt gattctggcg atggtagtgc tgtttgccat tgagtggcta ctgcggcgga
    16561 tcttccgcac aggcgcacac acccgtgggt ggtttgtcgg acgtaagcgt cgccgtgccc
    16621 gtaagcagac cgaacaggcg ctgctgaaac tagcggaagg cgattatcag caagttgaaa
    16681 agctgatggc gaaaaatgcc gatcacgctg aacaaccggt ggtgaactat ctgctggctg
    16741 ccgaagccgc gcaacaacgc ggtgatgaag cacgcgccaa ccaacatctg gaacgcgcag
    16801 cggagctggc cggcaacggc acaattccgg tagaaatcac ccgtgtacgt ctgcaactgg
    16861 cccgtaatga aaaccatgca gcacgtcacg gcgttgataa gctgctggaa gttacgccac
    16921 gccatccgga agtattacgt ctggcggaac aggcgtatat ccgcactggt gcatggagtt
    16981 cgctgctgga tatcatccca tcaatggcga aagcccacgt tggcgatgaa gaacatcgtg
    17041 caatgctgga acaacaggca tggattggcc tgatggatca ggcgcgtgcc gataacggta
    17101 gcgaaggttt gcgtaactgg tggaaaaacc aaagccggaa aacgcgtcat caggtggcgt
    17161 tacaggtggc aatggcggaa caccttattg agtgtgatga ccatgacacc gcccagcaaa
    17221 ttatcatcga cggcctgaaa cgccagtatg acgatcgcct gctgctgccg atcccgcgtc
    17281 tgaaaaccaa taacccggaa cagctggaaa aagtgctgcg ccaacagatc aaaaacgtgg
    17341 gcgatcgccc gttgttgtgg agcacactgg gtcagtcgct gatgaagcac ggcgaatggc
    17401 aggaagcatc gctcgccttc cgcgcggcgc tgaaacaacg tccggacgcc tacgattacg
    17461 catggcttgc cgacgcgctg gacagactgc acaaaccaga agaagctgca gcgatgcgcc
    17521 gcgacggttt gatgctgacc ttacagaata acccgtcaca gtaatctata tcgcctcgtt
    17581 cagaggcgat atttttttac caggatgtca aaattgcgca cgccgtcccg ctatcttttc
    17641 cgcttgccat cgcatgaaat tactcctttt cgggcaacgc tctttttaat cttgttgata
    17701 tgtgccgctc tggctggcgt aagttggttg attatttcct ttgtacgtac gggcaataca
    17761 ttcatcttct ggttaacact ttttattgga tatctgatag ctgcggcgaa gcaggaaaaa
    17821 atcaagatcc tcaagaagta ccgaatcatg gcagataaac gtcggggacg ctccatttgc
    17881 cagttcgccc gcgaatttga cacctacacc gtagatacat gggtgattcg tgcggtgtgg
    17941 gataccttgc aaggaaacgg ctatatcgat tacccactgc cactgaaagc cgatgatata
    18001 ctggacgatg atctggattt ggtgagcgac gcagtcgagt tagaagagct ggttgaagat
    18061 accgctgctc gttgcgggcg cgatctatgc ggaatagaag agaatccgtt tcttcctatc
    18121 gtcacggtag gctctcttgt aagagtgtta aacgcgcaac cgatgaccca ggagcgacgt
    18181 aaccagttct ttatccggtc ataaaaaaac gcctgctctt attacggagc aggcgttaaa
    18241 acaggtctgt atgacaacaa gtgggtgctt cactcaacgt tgtgtccatg gtgtctgatg
    18301 aggcataagc gacatctgtc agtggacgat aagcaccgta aacggctctg cgtcattccg
    18361 gagtttatga ggcactaagg cgaacataag agatggaatg agcatctact cgtttattat
    18421 gccacagaga accgggaaat aacatccctt aacacttgtt atgagataat tctgtaatcc
    18481 tctttgcttc ctgagtgaat atttctcctg cgcacgattc tacatatata tataatgaat
    18541 aataaaagtc attcaattaa taacatatat attaattgcc gttaaaacta aaaacagcat
    18601 caataatcaa cgcgatataa catcaccgcc ttacatatca cctgcgccag aggtaggatt
    18661 gaaaacgctc tcctgatttt ccaattcatt ttctggataa ataaataatt tattttcatc
    18721 actattattt atgcaatcat cctgtcaggg agagggatct caattatcaa tgcttaatta
    18781 cgtcaacatt ttgacgacat gaaaccggag cattttgcat ggaattttcg ttttcaccca
    18841 aacttcttgt tgtagctgtc gccgccgctc ttccactcat ggccaacgca gcagataccc
    18901 cgtcaaccgc caccgcacgc aaaggctttg ccggatacga tcacccaaac cagtatctgg
    18961 ttaaaccggc gaccactatt gccgacaaca tgatgccggt gatgcagcat cctgcacaag
    19021 acaaagaaac ccagcagaag ctggcagaac ttgagaaaaa aaccggtaag aaaccgaacg
    19081 tggttgtttt cttgctggat gatgtgggct ggatggatgt tggctttaac ggcggcggcg
    19141 tggcggtggg taaccctaca ccagatatcg acgccgttgc cagccagggg ctgattttaa
    19201 cttcggcgta ttctcaaccg agttcttccc caacccgcgc cacgattctt accggacaat
    19261 actccatcca ccacggcatt ctgatgccgc caatgtacgg gcaaccgggc ggtctgcaag
    19321 ggttaaccac tctgccgcag ttgctgcacg atcagggcta cgtcactcag gccatcggga
    19381 aatggcatat gggggaaaac aaagagtcgc agccgcagaa cgttggcttt gatgatttcc
    19441 gcggctttaa ctcggtatcc gatatgtata ccgaatggcg tgatgttcac gtcaacccgg
    19501 aagtcgccct gagcccggat cgttctgaat acatccaaaa actgccgttc agcaaagatg
    19561 acgttcatgc cgtgcgcggc ggtgaacagg aagccattgc cgacattacg ccgaaatata
    19621 tggaagacct ggatcaacgc tggatggaat atggcgttaa gttcctcgac aagatggcga
    19681 agagcgataa gcctttcttc ctctattacg gcactcgtgg ctgtcacttc gataactacc
    19741 caaatgcgaa atatgcgggt agctctccgg cgcgcacctc ttacggcgac tgcatggtgg
    19801 agatgaacga tatcttcgcc aatctgtata aagcactgga gaaaaacggt cagcttgata
    19861 acacgctgat tgtgttcacc tctgataacg gtccggaagc cgaagttccg ccgcacggtc
    19921 gcacgccgtt ccgcggtgcg aaaggttcta catgggaagg cggcgttcgt gtgccaacct
    19981 tcgtttactg gaaaggcatg atccaaccgc gtaaatctga cggcattgtc gatctggcgg
    20041 atctcttccc tacggcgctg gatctggcgg ggcatcctgg ggcgaaagta gcgaatttag
    20101 taccgaaaac cacctttatc gatggtgtgg accagacatc tttcttcctg ggaacaaatg
    20161 gtcagtctaa ccgtaaggcc gagcactact tcctcaacgg taaactttct gctgtgcgta
    20221 tggatgagtt caagtatcac gtcctgatcc agcaaccgta cgcgtataca cagagcgggt
    20281 atcagggtgg attcaccggc acagtaatgc aaacggcggg atcgtcggtg tttaacctgt
    20341 acaccgatcc gcaggaaagc gactccatcg gcgtgcgcca tatcccaatg ggtgtaccgc
    20401 tacagaccga aatgcacgcg tatatggaga tcctgaaaaa atatccacca cgcgcgcaga
    20461 ttaaatctga ttaagccggc gctatcgctg agatctgcct ttgccggatg cgatgctgac
    20521 gcatcttatc cagcctacag aacgctgcaa tttattgaat ttgcaaggat tgtaggccgg
    20581 ataaggcgtt cacgccgcat ccggcaatca accgcaggcg gccgccgatt tctacttatt
    20641 caccaccatc aaatgcgcct gcataatgtc gctggccgga cgaccgtgcg ccagcaaatc
    20701 agccattgct ttaagatatg gcggtagatg gcggaaataa cgctgatacc cggcacacaa
    20761 ataattcagc cccggtttgc cgctggcatc gagcataaag cggtgtttcg ggcagcctcc
    20821 ccaacatgct tttaacacgt tacaactgcg acactgcgct ggtaactgct taaatttatc
    20881 ttcaccaaac acctgctgtt gcggggaatc taccatttct gcaattgtct gctgaagcat
    20941 attccccagt cgatattgcg aataaacata gtgatcgcag gcgtaaacgt cgccgttgtg
    21001 ttcaacaatc accgagcgcc cacaggttgg ctgatgatgg caaaccgctc ctggcgcacc
    21061 gacaaaattg gcaaacgccc attcgatatt catcacgaaa atcttgccga cgtcgcgttt
    21121 gatccagtgg tcgaatatcg ccaccaaaaa ttcaccgaac tcatcggggc gtaccgacca
    21181 ttccgtcagt tcgccctgaa tatcgccggg agcatgtagc ttaagtccag catgagcagc
    21241 cgtttcatca gccaggcgct cgaccaccgg aataaactgg ataaactcaa cgcctgcatc
    21301 acacagaaaa tcatagattt gcaaaggttg taacgcactg gtgcgattta cgcagaccag
    21361 cacgttatag tcgacatgat gtttttgcag gagcgtcagg gcacgcatca ccagcttatg
    21421 cgttggtctg ccgcctttgg tcacgcgata ttgattgtgg atctcagccg gaccatccag
    21481 cgataaccca acaagaaaat gattttctgc cagaaatgca caccattcgt catcaagcag
    21541 aacgccgtta gtctggaagc tgttacttat cttcctgcca gcaccatatt tcgcctgtag
    21601 cgccacggct cggcggtaaa aatccagccc gagtaacgtt ggttcgccgc cctgccaggt
    21661 aaaagccact tcgttttggg tttcgctggc agcgatatag tgacggacat acgcttccag
    21721 cgtgtcatcg tccatatgcg tgactggctt ttcgcggtaa agggattgtt tttcgagata
    21781 aaaacagtag tcacagttca gattacaatc ggaaccgctc ggtttcgcca tcacatgaaa
    21841 agcacgcgtt ggaacctgtt gcagcatggt cgctccttgc ctgaagtcat ccttcaatac
    21901 gttaagggcg aaatcatacc gtaggacaat gagttattac gggcgtttat tgcgaacgga
    21961 gagtgatgaa atgcacagaa aacaaaaaac cccgccgaag cggggttcaa aattggtcgg
    22021 cgagagagga ttcgaacctc cgacccactg gtcccaaacc agttgcgcta ccaagctgcg
    22081 ctactcgccg aaatactgct ttttgaattt ttagttcaat tctttaaagt cgtggtgcga
    22141 ggggggggac ttgaaccccc acgtccgtaa ggacactaac acctgaagct agcgcgtcta
    22201 ccaattccgc caccttcgca ttgtcacaac ttctaataat ggggtggcta atgggattcg
    22261 aacccacgac aactggaatc acaatccagg gctctaccaa ctgagctata gccaccacta
    22321 caaatcttgt tacgcggtat tactaccacc gcagctcaag cgccgggact aaatggcgcg
    22381 cccgacagga ttcgaacctg agacctctgc ctccggaggg cagcgctcta tccagctgag
    22441 ctacgggcgc ttagcgccgt tgcgggggtg gataatacgg acttcccacc cctctgtcta
    22501 gtctcttttt aaataaattg cgcgtttggt tacggtttgt gcgttttgct gcttattcct
    22561 ccagtttatg cgctttaccg tggcgattaa gcccaaaaat tttataaatc gccgtcaccg
    22621 ccagcataaa gatgatgccg acaaacagcg acatacgcgt atcttcatta aagtacatgc
    22681 cgatcaaaac gcaaatcagg aatgccattg ttacgtagtt ggcccacggg aacaggattg
    22741 agcggaacgg atggctggca attgccgctt tatgcgcacg acgaaaacgc agctggctaa
    22801 tcaatatcac aaaccatggc accatccccg gaagcacgct ggcactgtag acgtagacaa
    22861 acacacgctg cggattggga atgatgtagt tcaggcatga gccaattagc agaatagcaa
    22921 tagatactgc cacacccgca accggtacgc cgtgacggga aactttcgcc attgccgccg
    22981 gtaactgacg gtttttcgcc agtgcataga gcatacgtcc gcaactgtac atgccgctgt
    23041 tacagccaga gagcgcagcc gtcagcacca caaagttgat aatgcccgcc gctgcggtaa
    23101 tgccgatttt ggcgaaagtc agtacgaacg ggctaccgtt gctgcctatt tcattccacg
    23161 ggaagatggt gacgataacg aaaatcgcgc caacgtagaa aatcaggatt cgccacagca
    23221 ccttgcctac agcactgcgc agcgtcacct gcggattctt cgcttcaccg gcagtaatgc
    23281 caatcagctc cacgccctgg taggacgcca ccacaataca caatgcggtc aggaaccctt
    23341 tccagccacc agcaaagaaa ccgccatgct ctgtgagatt gctaaaacca atcgactgcc
    23401 cgccattgcc aaagccaaag aaaatcacgc ccaggccaat gacaatcatc acgataatcg
    23461 tggtgacttt gatcatcgcg aaccagaact cgatttcgcc gtacaacctc accgccgcca
    23521 gattcgccaa cgccaccagc gccactgcga tcaatgcggg tatccactgc gccatctccg
    23581 ggaaccagaa ctggacataa acgccaatgg cggtgatttc tgagatcccc accgccatcc
    23641 acataaacca gtaagaccag gcggtgagat aaccaaagaa cgggctcata taacgatgcg
    23701 cgtaaacggc gaacgaaccg gtaaccggtt cgaggaacaa catttcgccc attgaacgca
    23761 tgatgaaaaa gacgaacagc ccggcgatga tataggccaa caatacagat ggcccggccc
    23821 atttcagggt actggcggcc cccataaaca ggccgacgcc aatggtgccc cccagggcga
    23881 tgagttcgat atgtcgagct tccagcccac gctgtagctc tggtttgtta tctgccataa
    23941 atcctcgtgt tgtgtttgca tgctttccgg tgttaccggt tatcgttatg ggtacatcga
    24001 gtgttgcgaa tgttttcgta attcaggaga aatggcaaat aaagcattaa aaatttgaat
    24061 gctttgtgta ataaaaaagc agacaggcga cggagtgacc actccgtcgc tttacaaaga
    24121 gaggaaaatc agaggttgcc ggtgtagtgc cagcgtaaat aacgcagcaa acgaagctga
    24181 cgcttaatgc ggctcggctg cgaaagcagg cggtagagcc actccagtcc cagcgtttgc
    24241 cagattttcg gtgcacgttt tacgtgaccg gtgaaaacat cgtaagtccc gccaacgccc
    24301 atatacagcg catccggatg caccagacgg cagtcgcgca tgaagatctc ctgctttggc
    24361 gatcccatcg caacagtgac gatttgcgcg ccgctggcat gaatgcgttc aaacagcgcc
    24421 tgacgctgct cgggtttaaa ataaccatcc tgactgccaa cgatattcac attccactgg
    24481 ttgcgcagtt tagcttcagt ttgcgccagc acttcaggtt taccgcccac aagaaatacc
    24541 ggtgtccctt ctttgcctgc gcgcgccatc agctcttccc agagatcggc cccggcaacg
    24601 cgggaaacct gcgcctgcgg gtacttttta cgtactgaac gtacaacgct gatgccatcc
    24661 gcatatttaa attcggcagc gttaattaac tcccggacct cggcgttatc ttcaatggtc
    24721 agcatttttt cggcattaat ggcaaccagc gttccctgct taagctgccc gtcagcaaac
    24781 agataatcga gggcgtgctg catatcacgc caaccaatca actgtaagcc acgcagtgta
    24841 taggtcggtg ccgtggtggt gttattcatt gttatccttc aatctgcgtc cggagcgatg
    24901 attttgtacg tttatgaatg agtccggcgc tttcaaaaag ccagtacaac agttttgcga
    24961 tcatcagaca tgcgccgaag accacgataa aaaagaccac gcgtgagaca aacgaatcca
    25021 gcccttcacg cgccagcacg atcatattga agatcgcccc gaagcagaaa ctgtgtaata
    25081 tcgcagcctt atagcgatta gtctcgcggt tgcccagctc atacagccag tcgaaccatt
    25141 tgatgatcag gccaaccaca atcgccccga gcgggatgaa caacgcgccg cccatcacca
    25201 ccagtgagcc tataagcgta ggcgagatcg ccagtccgga gtggttattc agcacttccc
    25261 aggtaaagta gttggctgag ttcagcacca tactcgggcg acccggccac agccaggaag
    25321 ggataaagac atagaaatcg cggacaatgg gagccaggcc ctggaagtcg atgttgtcgt
    25381 agttctgcaa cagcaacgcc agattctccc acggtgaaaa ggtgtcgcga gtgagataga
    25441 gaaacgtata gaacgcttca tcgccgctca cattcattcc atagcgtttt aacgccagcc
    25501 agaacatgcc cacaatcccc agcacacccg ccgccgccag catccacaac gaaatccagc
    25561 cgcgaataat gccaataaac aggaagatag cgaatgcgat gatgatattg gcgcgagtgc
    25621 cgccgacaat catataagtc agcaagccaa aggcgaccgt gctgacgagg aaaaacagcc
    25681 acgctttgct gtcctggcgc agaaaataaa ccaccagcat cgccgggatg aaaaagtaaa
    25741 agaagcgttt taatgccacg ccggagactt cgctggaaaa gatctgactg taagaattaa
    25801 gccggaacag caaaaagccg ttgtgcatga agaagatgcc gacgcttacc agcgcgatgc
    25861 ccatcaggat cacccacgtg agattggtct ccacgcggtt catggtaaac agcggacggc
    25921 gcggtgcatc agcaacgcgt ttgcgtagac gggttttgta ggtgacatag taaaccgcgt
    25981 agaagcagcc tgcagaaagc aacgcctgca acaagatttc tggcggcgcg acaccaacat
    26041 caaagcgaaa taccagcacg ctggtcagcg gaaagccgaa gaaaaaggtg agcaaaaaca
    26101 gcaatgaaaa gaagacattg aagttaaagc gcacacggcg aaactcaaac caggtcagcg
    26161 tggcaataaa cagcgtgcag agcagccaga caacaaaaag gccactgaat tgcagcagac
    26221 tcatgcgacc tccccggtgg caatcgccaa cgcccgctgc cagccttgta gatagttagg
    26281 gctaaagaag gcaatggtgt ttttatccac cgacgccagc tggcgctgcg cttcacgcac
    26341 aatatcctcg ttgagatcgt cggtagtaaa cagcaccggc aaatgttgtt ccgtcatatc
    26401 ctgccagaac ggattttccc ggttaagcac acaaggaatg cccgcctgaa tcagtaagca
    26461 cagcgtacca atgccctgct ggcgggcaaa aataaagtaa ccaagatcgc actgacgaag
    26521 tagcgtcaga taggcgtcaa attccagttt ttcgctcaga acttgcagat tttcttcgct
    26581 gaataactcc agccccgcct gacgaacttc ctcgatgtac gcttcgttat taggcggata
    26641 tcccatcggc accaccactt ttaccgtatc gccaaattgc tgatgaacgg cgcgcaagac
    26701 agcaatatgc tcattgctgc ggtcgccgga gttgcccacc agaatggtca ttttcccttc
    26761 acattgccga tcgttcgcca tcgtattaag agaagggtcc atccgcgtcg ggaagtacag
    26821 cagttctccc cgcacctttg gatgcgtttt ggcaaaaaag ctcaaatcac cgcgggtggc
    26881 aaatacacag ccgactctct tttgcgccag gcgacgtagc gggtaaaaaa gcttatatct
    26941 caagccactg gaaagttcgt acaggtctgc tccccagata tgccagaaaa actggctggg
    27001 cttaatgcca ccactcagca gagccagcca cagtttggga ttgaactgac cgtggaagaa
    27061 aaaacgctgc tgacggttag cttttgcttt cgcgatgacc gcttccgcca gcgatttttt
    27121 cccagggaaa aattgcacag aaagcgccgg acagctatca cttaagccgt cgtccttgcc
    27181 aacaaccata aactcgcgcg cgtgctcgct cgtcgcggcc agcgcgtcgt tgaaaaaccg
    27241 cagaacggtt cggttatggt gagggatatc cgatcccagt acgtgaatca gtacagtcat
    27301 gcccgcctac gccagagtaa aaacacgcca caacaaagag aaaaatagac gatataggtt
    27361 gccatatagg cctgtgctgc gcccagtgcg ccatgcgcag ggattagcca gtgggcaaat
    27421 accatcaata aagtgaactg gctgatttcc gccagaatat aaaaccgcag tgacgctttg
    27481 gcgatcacca gataaccaaa gacataagcg cccactttta acacatcacc cactaactgc
    27541 caggcaaaga gatcgcgcat agcggtaaat ttattcgaca acagcagcca gatagcaaaa
    27601 tcacgcagca accagacggt aaaactcgcc gccgccactg ccggtaagac gaatttcagc
    27661 gatttaacca cttcccgggt gatatcgcgc ttttccgtta gccgcgacaa cgtgggcagc
    27721 aaatatacgc tgaacgatgc cgtaataaat tgcaggtagg catcggaaat actgctcacc
    27781 ccttgccaga tccccacctc atcccagcta tactgcgccg ccagcagttt acgcatcatg
    27841 atgtaagcaa caggcaaggt caccgacgta atcaacgcca tgagcgtaaa tttgctcaac
    27901 tgccctgcca gaccgttatc ccagctgggt ttcagatagc ttaacgggat gacaccacgc
    27961 ttgatcaaca tgatggcggc aggaattacc accagcgcgg gaatcaacgc cagccccagc
    28021 aacgcccctt cataaccgcc caaacggtaa ctgacgtagt acgcaagaac gccaatcagg
    28081 ctgccgacaa tcagggataa cgcattacct gcggcatcgc gaaagccttt catcaacgcc
    28141 agtaacaggt tgccccaggc gatccccatt tgcaccaacg ccactaaacg caccagcccc
    28201 tgatagtcgg tattaccgaa caatccctgg ctgattggcg cagctgccag cacaaaaacc
    28261 agcgccatta gcatagagaa gccaagtacc atcgctgatg aagtgccgac cacgcggcgc
    28321 agctgctgcg gattatcatg gtactgagca acgtatttgg ttacgccatt aaagatgccc
    28381 gccccggcaa gcacgccgag cacggtaatc aactggcgga aatttgccgc cagcccaagc
    28441 cccgcaggac caaatgacac cgccagcaac ttaccgacca gtaacccggc accaatcttg
    28501 accagtgtac tggccgccgt ccacaaggac gcttttgcca acgacatatc aggagaagta
    28561 gttcaacaag gtcgcaatta ccgtgcgctg attgacgggc gacaggttgt agaacaacgg
    28621 caggcgcacc aggcgctcgc tctctttggt ggtgtagcga tcttcaccgt ggaactcacc
    28681 aaagcgttct cccgcagggc aaccgtgcag cggaatgtaa tggaacaccg ccatgatttc
    28741 cgcttctttc agaaagttaa tcaacgcgct ccggtcatca atatcccgca gtttaatgta
    28801 gaacatatgc gcgttctgca cgcagccatc gggaatcgac ggcagctcga tacgcccggc
    28861 tttcgccaga ggcgctaacg catcgtagta gttttgccac agcgccagac gttgctggtt
    28921 gatacgatcc gctgcctcca gttgcgccca caggtacgca gcttgcagat cggacatcaa
    28981 atagctggag ccgatatcgc gccaggtata tttatcgacc tgaccacgga agaactggct
    29041 gcggttagtg cctttttcac ggatgatctc ggctcgttcg atcaacgctt tatcattaat
    29101 cagcgtcgcg ccgccttcac cgcccgccgt gtagtttttg gtttcatgga agctaaagca
    29161 gccaatatga ccaatggttc ccagcgcacg ccctttgtaa gtggacatca cgccctgagc
    29221 ggcatcttcc accacaaata gattatgctt cttcgccaac gccataatgg tgtccatttc
    29281 gcaggccaca cccgcgtaat ggaccggcac gataacgcgc gttttgtcgg tgatcgccgc
    29341 ttcaatcaac gtttcgtcga tgttcatggt gtccgggcga acatccacaa aaacgatttt
    29401 cgcgccacgc agcacaaatg cattggcggt ggagacaaag gtgtagctcg gcatgatcac
    29461 ttcatcgcca ggctggatat cgagcagcag cgccgccatc tccagcgaag cggtgcagga
    29521 cggcgtcagt aacactttgg cgctgccaaa acgttgctcc agccactgct ggcagcgacg
    29581 ggtaaaaccg ccatcgccac acagtttgcc gctacccatt gccgactgca tatagtcgag
    29641 ttcggtaccc accaccggcg gtgcgttaaa tggaatcatg tgatcacctg tataaccagt
    29701 acgcggtgct ttctacattc gcaccacttt gtatgtatcg tttaagcgcg gcggtgttgc
    29761 ccatctgggt cgccacccgc aaagttgttt taccgcgagc atacgcccag tttagcgccg
    29821 tttgcattag ctcagcacct gcaccgcgtc cagccagcag gccaattcgc gcatctgtcg
    29881 cattgagttc ccgtaaagag acataaccgc gaatatcgcc ggacgccgca cgtaaaatca
    29941 gacattgatg atcaaaggtg ccgcgcacgg cattttcaat ccactgtgca taaaagcgac
    30001 cgctggcgtc aggcgcatac cacggcgcac gaaaacggct ttgcgcaaat gcggcgctgg
    30061 ctaactgacg taatgcggga atatcggtct cttgtgccac tactgcacca ctatcactga
    30121 cattgttcac gggtagcgcc aaatcaactt caccttctac cagggagaat cccagctgct
    30181 gcagggcatc cagttcaccc gtatttgatg ccgcaatttt ggcctgcacc cgtgaccacg
    30241 gcgctaacgc gtctgacgtc aggagcggtg cttcagtcgt gatgcgcacg atggcgctgt
    30301 taacaccaaa gaaggcgttt tcccaggtta gtggctcaat actggcgcgg acgggcacga
    30361 agtaactcca gcagatattg gccgtagcca gttttcgcta atgaactggc agcacgcttc
    30421 acaccctcgt catcgagcca gccgttacgc caggcgatct cttccaggca ggcaatctta
    30481 aagccctggc gtttttccac cgtctgtaca aaggtactcg cttcaatcag gctgtcgtga
    30541 gtaccggtgt ccagccaggc aaatccgcgc ccgagcagtt caacggtcag gttacccgcc
    30601 tcgaggtaca tctggttgat ggaggtaatc tccagttcac cacgctccga cggcgtcacc
    30661 tgctttgcgt actccacgac tttactgtcg tagaaataaa gcccggtcac cgcccagttt
    30721 gatttcggct gttttggctt ttcttccagc gagatagcgc ggaaattgtc gtcaaactcc
    30781 accacgccaa agcgttccgg gtccattacc tgatagccaa atactgtcgc cccttccgtg
    30841 cgcgccgcaa catgacgcag cttcggactg aagccctgac cgaagaaaat gttatcgccc
    30901 agcaccagac aagaaggttc accgttgagg aaggtttcac cgatgataaa ggcctgcgcc
    30961 agaccgtccg ggctgggctg ttcggcgtat tccagctgga taccgaactc actaccatcg
    31021 cccagcaggc gctggaaata acctttatct tccggcgtag taatgatgag aatttcgcgg
    31081 ataccggcca gcatcagcac cgacagcgga tagtaaatca ttggcttatc gtaaatcggc
    31141 aacagttgct tcgatacgcc gcgcgtaatc ggatgcaatc gggtgccgga accgcccgcc
    31201 aggataatac ctttcatgtt tgcctccgct gaaaattagc ctttcagacc taaacgctcg
    31261 ccctgatagc tgccgtcctg cacctgcttc caccagattt cattagccag ataccactgc
    31321 accgttttac gcattccact ttcaaaggtt tcctgcggca gccagccaag ttcacgggca
    31381 attttcgaag catcaatggc ataacgcaga tcatgccccg gacggtcagc gacaaaggtg
    31441 atcaggtcac gatagtgcgc cacgccgtgc ggcttgttcg gagccagttc ttccagcagc
    31501 tcgcaaatgg tttccacaac atcgagattc ttacgctcgt tgtgaccacc aatattatag
    31561 gtttcaccga ctttcccggt ggtcgccacg caatacagcg cgcgggcgtg atcttccaca
    31621 tacagccagt cacggatttg ctgcccgttg ccatataccg gcagcggttt acccgccagc
    31681 gcgttgagga tcatcagcgg gatcagtttt tccggaaagt ggtaaggacc gtagttattc
    31741 gagcagttgg tgataagcgt cggcagacca taggtccgca gccaggcgcg caccagatgg
    31801 tcgctgctgg cttttgacgc ggaataaggg ctactcggcg catacggcgt ggtttcggtg
    31861 aagaaatcat ccgtcgagtg caggtcacca tatacttcgt cggtggagat atgatgaaaa
    31921 cggaacgctg attttttatc ttccgtcagc gcattccagt aagtccgcgc cgcttcaagc
    31981 agtgtataag tcccgacaat gttggtttca ataaacgctg ccgggccgtc aatagaacgg
    32041 tcaacatggc tttcggctgc cagatgcatg acacagtctg gctgatactc agtgaatacg
    32101 cgcgccagtt ctgcccgatc gcagatatca actttctcaa aggcaaagcg ctcgctttgc
    32161 gcgaccggtg ccagcgacat cagatttccg gcgtaggtca gcttatcgac cactatcacc
    32221 gcgtcgctcg tttcgttgat gatataacgc accagcgccg agccaataaa cccggcacca
    32281 cctgttatca gaatctttct catcagcgcc aaactccttt ggcatcgacg acatactgct
    32341 gatggacatt gtcgccattg ataactttga actgactatg atcgaccagc atcaccagca
    32401 cgtctgccgt tgccagcgcc tcgtcaagct gcgccagagt acaaagcccg gtcagttttt
    32461 tcggcaactg gtggatgtta ggctcaacaa ccagcgtttc gccgctatgc cactgggcga
    32521 tcagttcagc gatttccatc gccgggcttt cgcgcaggtc atcaatattc ggtttaaacg
    32581 ccagaccaaa gcaggcgatt ttcagttcac tggcgcgttt atcggtagca gcaaggcagt
    32641 cggcaaccgc cgctttcacc tgatcgataa cccagaacgg tttgtgatcg ttcacttcgc
    32701 gcgcggtacg gataagccgc gcctgctgcg ggttctgtgc cacgataaac cacggatcaa
    32761 cagcaatgca gtgaccgccc acgccaggac caggctgaag aatattaacg cgagggtgac
    32821 gattcgccag gcgaatcagt tcccagacgt taattccctg atcggcacaa atcagcgaca
    32881 gttcgttagc aaaagcgata ttcacatcgc ggaagctgtt ttcggtgagc ttacacattt
    32941 ccgccgtccg cgagttagtg acgacacact caccttcgag gaaaattttg tacagttcgc
    33001 tggcgcgggc cgaacaaacc ggcgtcatac caccaatcac gcgatcgttt ttaatcagct
    33061 cgaccataac ctggcccggt aacacgcgtt ccggacagta agcaatgttg acgtccgcca
    33121 actcgcccac ctgctgtggg aaagtgagat ctggacgcat ctctgctaac cattctgcca
    33181 tcttctcggt tgaccccacc ggcgaggtgg attcaaggat caccagcgcg ccttttttca
    33241 gcactggcgc aatggagcga gcagccgatt caacgtaggt catatctggc tcatgatcgc
    33301 ctttaaacgg cgtgggtaca gcaatcagcc aagcatccgc ttcaactggc gtcgtgctcg
    33361 ctcgtaaaaa accgccttct acggcagttt ttactacgct cgccaaatca ggttcggcga
    33421 tatggatttc gccacgattg atggtatcaa ccgcgtgttg gttgatatcg acaccaatca
    33481 cctgtttttg ccttgaggca aacgcagctg ctgtaggcag cccgatgtaa cccagtccga
    33541 taacagaaat ggtcgcaaaa ctcatagtga tatccgatta ttttttaacg cttccagaat
    33601 gcgagagcat gcctgaccat caccatacgg gttatgggcg cggctcatag cttgatattc
    33661 gttttcgtct tttaaaagac gcgtcacttc ctcgacaatt cgctgcttat ccgtgccgac
    33721 cagacgcacc gtccccgctg tcaccgcttc cggacgctca gtggtatcgc gcatcaccag
    33781 caccggtttc cccagcgaag gcgcttcttc ctgaatgccg cctgagtcgg tcaaaatcag
    33841 ccaggcgtgg ttcatcagcc agacaaacgg taaatactcc tggggatcga tcagaatgac
    33901 atttttcaca tgccccagaa tgcgattgac cggctctctg acgttcgggt tgagatgcac
    33961 tggatagaca atctggatgt cctggtgcgt gatggcgatg tctgccagcg cctggcagat
    34021 ttcttcaaag ccacgaccga agctctcacg cctgtgaccg gtcaccagaa tcatcttttt
    34081 atcggggtcg ataaacgggt aatttgccgc cagttctgaa cgcagcgtgt cgctgctcat
    34141 cacctggtca cgcacccata acagtgcatc gatgacagta ttaccggtaa tgaagattcg
    34201 gctgtcagca acgttttcac gcagcaagtt ttgccgggaa gtttcggttg gagagaagtg
    34261 atacatcgcc agatgcccgg tcaatgtacg gttagcctct tccggccacg gcgaatagag
    34321 atcgcccgtg cgcagacctg cctcaacgtg accaactgga atacgctgat aaaacgccgc
    34381 caggctggtt gccagcgttg tagtagtatc gccgtgaacc agcacgacgt ctggtttgaa
    34441 ctcggcaaga ataggtttta gcccttccag aatccgacag gttatctctg tcaggccctg
    34501 tcctggctgc attatgttga gatcgtagtc aggtacaatg gaaaagagtt tcagcacctg
    34561 atcgagcatc tcccgatgct gcgcagtgac gcaaacttta gcctcaaaaa aaggatcttt
    34621 tgccaacgca tgcaccaacg gagccatctt gatggcttcc gggcgcgtac caaatacagt
    34681 cagtactttc acatcgattc tcttcgaata agcggcgagc gcctttgcgc tcaccacagc
    34741 agtgttgcta tttcgagcaa cggcgggtta atgcgacacc agccccgatc agccccccga
    34801 caatgcccca cataatcatc aggaaggcac gacgtgggct atcgcgtttt accggttctt
    34861 ccggcgtacg caaatagcga taggtctgaa aacgcggatc cagggttgga ccaacattca
    34921 gggtgtttaa catggcccga ttctgatcat agtcgagatc aaaggccgga ccgacggcct
    34981 gtaaattttc cagtcgagcc tggagcattg gacgcccaag caggaacatt tctgaatcag
    35041 gtaactcctc ggcaggcaca tctgtcgcac tgcgcgaaat attatgctgc tcagcaattt
    35101 tcagcgcctg ttcaatactg ttcatccggc ggtcgtagat ggctttcgcc acctcttcct
    35161 gacgcttcac ctgagctttc atctggatgg tgcgcgccgc ccatgcacct ttcagctcat
    35221 cattcagatg gctggctgca cgctggctgg caaaagcaac atactgacgt aacaggttat
    35281 tagcgtcagg cgcggtttcg gcaatcagct tcacgctgtc attgaccgcg cgggtgaagt
    35341 caccgggaat aaacacgatg ttgttgatca tttcatccag caacgccgca tcggctttgc
    35401 tattgcccac catccgctgt ttgtaatagt cggtttgcag ccagaactct ctgcgggtat
    35461 cccacgaggc cagttgcata acaaactctt tataggcttc gtccatgacc gatggttggt
    35521 cggcagaagc catgtttgaa cggacatcca ggttacgcaa aaattgctgc tgcgagtaat
    35581 atccccccag catattcacc gttggacgat cggtaatcgc cgtcgagctc cactcctgac
    35641 gagcaaaaaa agtatacgcc agcgcgatta acgcaaacgc cagccccatg ccaataatcc
    35701 acagcttccc agcccacaag gtacgaaaca acccacgaat atccagttca ttttcagcgt
    35761 cttcggccgg tttcccaggc attggttgtg tcatcacatc ctcatttatt tggttaaatt
    35821 ggggctgcca ccacgatttc tacgcagtct gcgttttacg cgcttaataa agcgagcaac
    35881 tttccaggca cgcttgatgc aatatccata gaggaagaat gctagcaaaa agagcaccag
    35941 catgacccac tccgggacaa aatgagaata ttctgccagc acgccaatgg aagcgagcag
    36001 tgctgcggca agggtaatca gcacaaacgc ctggcgggaa gtaaacccgg cacgcatgat
    36061 caaatggtga atatgctgac ggtcaggaga gaatgggctc atgcctttac gcaggcgacg
    36121 gtacataatc gccaccatat ccattagtgg aatggcgatt atccacaaag cggtaaccgg
    36181 gctgatggga tgagttttgc cctgggtcgt ttcgagcagg atccagataa cggtaaaacc
    36241 aatcagcgta ctgcccgcat cccccataaa gactttgtag cggcgaccca ggataccaag
    36301 gttaagcatg atgtatggca ggatggcggc gatcatcgca aaacaccaga ttgcaaggct
    36361 ggtttgcccg tcgaaccaca aaatcatacc gattgctgca aacgagacgc aggacaaccc
    36421 gcccagcaag ccatcaatgc catcaaccat gttgaacgca ttaatgaccg cccagacggc
    36481 aaatagcgtc aggaagtagc caaacggtcc gagcaccatc tcccaggagc caaagatata
    36541 acccaggcta ctgagataaa gtttgccgaa caccatcata acaatgccaa cagcggcctg
    36601 tatggtggca cggattttta cgctgatatc aaaacggtca tccagcgcgc caatgaaaac
    36661 aagcacaccg gcacaagcga gatagagaga tgcatgcgga atatagtaat cgacaattcc
    36721 gaacgtgaag caaatccctg cataaaccga aataccccca acgagaggta tcaatccctg
    36781 gtgacgtttg cggaagttag gtttatccac taaaccgact ttttttgcta cctttcgggc
    36841 aaaaaacaga aacagtgtcg tgaataaaaa aatactgatg agatcagtac tcactgtcag
    36901 taaattcaca atgcatgctc tcagagaaaa ttattagcag aagtataacc acgaaggctt
    36961 ttattcagaa gggaaactct gctctgaacc caccaacctt gtgcaaaaaa caaccacgtg
    37021 attcgtgtta tgcgcaataa acaaacataa ctcgtatttg ttataacgcc gttaagatta
    37081 cagatataaa aacaaaacgc cacgtaaaca cgtggcgttt ttggcataag acaaatttat
    37141 gagcgtttca tcatttcgaa gaaatcgtca ttggtcttgg tcattgccag tttattaatg
    37201 aggaattcca ttgcgtcgat ttcgcccatc gggtgaatga ttttgcgcag gatccacatt
    37261 ttctgcagct cttcctgagt ggtgagcagc tcttctttac gggtaccgga acggttgtag
    37321 tcgatagccg ggaagacgcg tttttcagca atcttacgag aaaggtgcag ttccatgttc
    37381 cctgtacctt taaactcttc gtagataact tcgtccatct tggaaccggt atcgataagc
    37441 gcggtagcga tgatggtcag gctgccgccc tcttccacgt tacgcgccgc accaaagaag
    37501 cgtttcggac gatgcagagc attggcatcc acaccaccgg tcaacacttt acctgacgcc
    37561 ggaacaacgg tgttgtaagc gcgcgccaga cgagtgatgg agtcgagcag aatgataacg
    37621 tctttcttgt gctcaaccag gcgtttcgcc ttctcgatca ccatttccgc aacctgaacg
    37681 tggcgagatg cgggttcgtc aaaggtagaa gcaacaactt caccttttac cagacgctgc
    37741 atctcggtga cttcttccgg acgttcgtcg atcagcagaa ccatcagcac acaatccggg
    37801 tggttgtaag caatgctctg agcaatgttc tgcagcagca tggttttacc ggctttcggc
    37861 ggtgccacaa tcagaccacg ctgaccacga ccgataggtg atgccaagtc cagtacgcga
    37921 gcggttaaat cttcagtaga accgttacca cgttccatgc gcagacgaga gtttgcgtgc
    37981 agcggggtta agttctcaaa gaggattttg ttgcgggcgt tttcaggttt gtcgaagtta
    38041 acttcgttaa ctttcagcag cgcaaaatag cgttcacctt ctttcggcgg gcgaatctta
    38101 ccagagatgg tatcaccagt gcggaggttg aaacggcgga tttggctagg agaaacgtag
    38161 atgtcatcag gaccggcgag gtaggagctg tctgcggaac ggaggaaacc aaatccatcc
    38221 tgcaatatct ccagtacgcc atcaccaaag atatcttcgc cactctttgc gtgctgcttc
    38281 aggatggcaa aaataatgtc ctgcttacgc atacgagcca ggttttccag ccccatattt
    38341 tcgccgagag tgatcagctc agaaaccggc gtattcttta attcggtaag attcatagtg
    38401 gtgtgagttc ttaaacttgg ggtaaatctc gaacttaatg ttgtgaatgg tatggcagga
    38461 tcatccatgc ctgtttacgg tcatcgactc atgtcttttc gctgcctggt cacaggagag
    38521 tacgcagaac tgaaacgaca agacggattg agtgacgagc cagaaatctg ttcacttcgc
    38581 atttaagata aaacgggaag cgttggaaat tacaagattc aaacttaata aggtatgttt
    38641 aatacgaagt caacactaag ttagcatgac tcacgccggg cgtccagttt ttagcgacgg
    38701 ggcacccgaa catgaaattc ccttacgcca ggttagcgtc gaggaactct ttcaactgac
    38761 ctttagacag tgcgcccact ttggttgccg ccacttcacc gtttttgaac agcagcagag
    38821 tcgggatacc acggatgcca tatttcggcg cagtgccagg gttttgatcg atgttcagtt
    38881 ttgcaacggt cagtttgccc tgatattcgt cagcgatttc atccagaatc ggggcgatca
    38941 ttttgcacgg accgcaccac tctgcccaga aatcaacgag gatcgccccg tccgctttga
    39001 gtacatccgt gtcaaaactg tcgtcagtca ggtgaataat tttatcgctc atatataact
    39061 ccacaggaat aagcctggcg tgttggtttc gttgttggtg taacattaac caactaaagg
    39121 ttgactttat ttcaccggat acgctttcgt aaagcaatag taagctgata ttctaccaca
    39181 ctatgagcaa aacacattta acagaacaga agttttccga cttcgccctg catccgaagg
    39241 ttgtagaagc ccttgaaaaa aaagggtttc ataactgtac gcccattcag gcactggccc
    39301 ttccgctgac gctggcgggt cgtgacgtag ccgggcaggc gcaaaccggt accgggaaaa
    39361 cgatggcgtt tcttacgtca acgtttcatt atcttctctc tcatcctgcg atagccgatc
    39421 gcaaggtgaa tcaaccgcgt gccttaatta tggcaccgac gcgtgaactt gccgtgcaga
    39481 tccacgccga cgcggagcca cttgcgcaag ctaccggcct gaagctgggt ctggcttacg
    39541 gtggtgatgg ctacgacaaa cagctgaaag tgctggaaag cggcgttgac attctgattg
    39601 gcaccacggg tcgtttaatt gactacgcca agcagaacca cattaacctc ggagccattc
    39661 aggtggtggt gctggacgaa gccgatcgca tgtacgatct gggctttatt aaagatatcc
    39721 gctggctgtt ccgccgtatg ccacctgcaa accagcgcct caacatgctg ttctccgcca
    39781 cgctttcgta ccgggtacgt gaactggcgt tcgagcagat gaacaatgcc gaatatattg
    39841 aagtggaacc ggaacagaaa acgggccacc gtattaaaga agagcttttc tacccttcta
    39901 acgaagaaaa aatgcgtttg ctgcaaacgc tgatcgaaga agagtggcca gacagagcga
    39961 ttattttcgc caacaccaaa caccgttgtg aagagatctg gggccacctg gcggcagatg
    40021 gtcatcgtgt cggtttgttg acaggcgatg tcgcgcagaa aaaacgtctg cgtattcttg
    40081 atgaatttac ccgtggcgat ctggatattc tggttgccac cgacgttgcc gcgcgtggcc
    40141 tgcatatccc ggctgtgacg cacgtcttta actacgattt acccgatgac tgtgaagatt
    40201 acgttcaccg tattggtcgt acaggtcgcg caggcgcaag cggtcattcc atcagcctgg
    40261 cgtgtgaaga gtatgcattg aatttgcctg ctattgagac ctatattggt cactcaattc
    40321 cggtaagcaa atacaatccg gacgcattga tgaccgatct gcctaaaccg ctgcgcctca
    40381 cgcgcccgcg tacaggcaat ggtccgcgtc gtactggcgc tccgcgtaat cgtcgtcgtt
    40441 caggttaaat aaaaatgtca tactcaaaat cattcaaact gtatcaagat ggcaagagaa
    40501 tgaatcccga tgcgcatgct gtagtaagtg atttgggtga aagaacgcag ccaacgcaga
    40561 gacagattga aggatgaaga gtatgggttc cacctcgtcg ctgtatgcag ccattgatct
    40621 cggttcgaat agttttcata tgctggttgt gcgcgaggtg gctggaagca tccagacgct
    40681 gacgcgaatt aaacgcaaag tgcgtctggc tgctggcctg aatagcgaaa atgccctctc
    40741 taatgaagca atggagcgcg gttggcaatg tctgcgcctg tttgctgaac gtctgcaaga
    40801 tatccctccc tcgcaaattc gcgttgtcgc tacggcgaca ttacgactag ccgtcaatgc
    40861 gggtgatttt atcgccaaag cacaggaaat cctcggttgt ccggtacagg tgatcagcgg
    40921 tgaagaggaa gcacgtctga tttatcaggg cgttgctcac acaactggag gtgccgatca
    40981 gcgcctggtg gtggatatag gcggtgccag tacggaactg gtaaccggca cgggtgcaca
    41041 aaccacctcg ttgttcagcc tgtcgatggg ctgcgtcacc tggctggaac gctattttgc
    41101 cgatcgtaat ctggggcagg aaaattttga tgctgcagaa aaagcggcac gcaaagtgtt
    41161 acgtccggtt gccgatgaat tacggtatca cggctggaaa gtgtgcgttg gcgcttccgg
    41221 caccgtgcag gcgttacagg aaatcatgat ggcacagggg atggatgaac gcattaccct
    41281 ggaaaagttg cagcaactga aacaacgcgc cattcattgc ggtcggctgg aggaactgga
    41341 gattgacggg ctgacgctgg aacgtgcgtt agtgttcccg agtggtctgg cgatcctgat
    41401 agccattttt accgaactga atattcagtg tatgaccctg gcgggcggtg cgctgcgtga
    41461 aggcctggtc tacggtatgt tgcatcttac cgtcgagcag gatattcgca gccgtacgct
    41521 gcgtaatatt cagcgccgct ttatgatcga tattgatcag gcacagcgcg tagccaaagt
    41581 tgcggctaac ttcttcgatc aggtggaaaa tgaatggcat cttgaagcaa taagccgcga
    41641 tttgctcatc agcgcctgcc agcttcatga aatcggcctg agcgttgact tcaaacaagc
    41701 gccgcaacac gctgcttatc tggtgcgtaa tctggatctt cccggtttta cccccgcaca
    41761 gaaaaaactg ctggcgacgc tactgctcaa ccagactaat ccggtcgatc tctcatcgct
    41821 gcatcagcaa aatgccgtac caccgcgcgt cgcagaacaa ctctgccgtt tactccgcct
    41881 ggctatcatt tttgccagcc gtcgccgtga cgatctcgtg ccagagatga cattacaggc
    41941 taaccatgaa ctgttgacct tgacgcttcc gcaaggttgg ctaacccaac atccgctggg
    42001 taaagagatt attgatcagg aaagccagtg gcagagctat gtccactggc cgctggaagt
    42061 gcattaatga gtaagtgccg gatgcgatgc tgacacatct tttccggcct tgattatttc
    42121 cctcgttttg ccgccatcat cgctttcaga ttcgccagat ggctttgccc tttctgcatc
    42181 cgttcttcgg cgctgaccac tttacgctcc tgttcccaaa tcaaatcatc ctgcggcagc
    42241 tccagtaaga agcggcttgg ctccggacgc accagctcac cgtactgacg acgctcttta
    42301 cacagcgtaa aggtcaattc cttctgggcg cgggtaatgc cgacataggc cagccgccgc
    42361 tcctcatcga tattatcttc atcgatactg ctctggtggg gcaaaaatcc ttcttccata
    42421 ccaaccatgt agacataggg aaactccagt ccttttgacg cgtgcaaagt catcagttgc
    42481 acctgatcca gctcttcctc gctctcgccg cgctccatca tgtcgcgcaa agtaaagcgc
    42541 gtcaccacct gggtgagcgt catcggctca tccagttcgc tgccttccag catctccgtc
    42601 atccagctaa acagttggtt gacgttcttc atgcgcattt cggcagcttt cgggctgggc
    42661 gatgtttcgt acagccagga ttcataatcc atgccgtgga tcagatcacg caccgcggca
    42721 atcggctccc gctccgccag acgctggatt tccgccaacc agtgagtgaa gcgggtcaat
    42781 gcttcataac cacgtccgct cagggtctga ctcaggccca tatcaaagct ggcggtaaac
    42841 atgcttttat tgcgcgtcat cgcccactca cccagctttt tcagcgtagc cgggccaatc
    42901 tctcgcttcg gcgtgttaac gatacgcagg aatgcgctgt catcgtccgg gttagtcagc
    42961 acgcgcagat aagccagcaa atccttgatt tcagggcgag agaaaaacga cgtaccacca
    43021 gaaattttgt acgggatgcg gttttgcatc aggaattttt caaacacccg cgactgatgg
    43081 ttgccgcgat aaagaatggc gtaatctttg tactgcgttt tattgacgaa gtgatgcgcg
    43141 atcagctcgc cggtgacgcg ctcggcttca tgttcctcgt tattcgcgct taaaactttt
    43201 agctctgtgc cgtaacccag ttcggagaac agacgctttt caaagacgtg cgggttattg
    43261 gcgatcagga tgttcgccgc tttcaaaata cgtccggaag agcggtagtt ctgctcaagc
    43321 ttaatcacct tcagcgcagg aaaatcctgg ctcagcagca ccaggttttg cggacgtgca
    43381 ccgcgccagg agtagatcga ctgatcgtca tcgccaacta cggtaaagcg cgcgcggctg
    43441 cccaccagca gtttcaccag ttcatactgg ctggtgttgg tgtcctgata ctcatccacc
    43501 agcaggtagc gaattttgtt ctgccagcgc tcgcggactt cttcattgcg ttgcagcagt
    43561 aacgtcggca ataaaatcag atcatcgaag tcgagaacgt tacaggcttt caggtgtgca
    43621 tcatacagcc cataacaatg ggcaaaaata cggtcccgct cgccaatcgc actggctgcc
    43681 gcctgggacg gtgttttgag atcgttcttc cagttagaga tggtcgaaat cagctgttgc
    43741 aggaggactt tgtcatcttc aatcagcccc tcggtcagct ctttaagcaa cgccagctga
    43801 tcggtgtcat caaacagcga aaagttcgct ttcatcccca acgccgcata ctcacgcttg
    43861 atgatatcca gccccagcgt gtggaaggtg gaaatcatca gtccgcgcgc ctctttgcgc
    43921 cccagcgtct gcccgacacg ctctttcatc tcgcgcgccg ccttattggt aaaggtcacc
    43981 gccgcgatat gtcgcgcctg ataaccgcaa ccgcggatca gatgggcgat tttattggtg
    44041 atgacacgag ttttaccgga acccgcgccc gccagcacta ggcaggggcc ggtaacgaat
    44101 tcgacagctt gttgttggcc ggggtttaga cgcataggaa aatcgctcaa tgaaagtcgg
    44161 gaggggaaaa taacagcgtg gtagtatagc cagcctcatc cttaccactc aaggcacgat
    44221 catggcaaaa acagcagcag cactgcatat ccttgtaaaa gaagagaaac tggctctgga
    44281 tcttctcgag cagattaaga acggtgccga tttcggcaag ctggcgaaga aacactccat
    44341 ttgcccgtca ggtaaacgcg gtggtgattt aggtgaattc cgccagggcc agatggttcc
    44401 ggcgttcgat aaagtggttt tctcttgtcc ggtactggag ccaatcggcc cgctgcatac
    44461 ccagttcggt taccacatca ttaaggtgct ttaccgtaac taatagcaag gccttctccg
    44521 ggagaaggcc ttgaactctg aatcgcactt aacctgcaac agcaatacgt ttcatatccg
    44581 tcatatagcc gcgcagtttc ttacctacct gctcaatcgc atggctgcga atcgcttcgt
    44641 tcacatcacg caactgcgcg ttatctaccg caccttccgg aatagcttta cccaggtcgc
    44701 ccggttgcag ctctgccata aacggtttca gcagcggcac acaagcgtaa gagaacagat
    44761 agttaccgta ctcagcggta tcagagataa ccacgttcat ttcgtacaga cgcttacggg
    44821 cgatggtgtt ggcaatcagc ggcagctcgt gcagtgattc atagtaagca gactcttcaa
    44881 tgatgccgga atcgaccatg gtttcgaacg ccagttcaac gcccgctttc accatcgcga
    44941 tcatcagtac gcctttatcg aagtactcct gctcgccgat tttaccttca tactgcggcg
    45001 cggtttcaaa cgcggttttg ccggtctctt cacgccaggt cagcagtttc ttatcatcgt
    45061 tggcccagtc cgccatcatg ccggaggaga attcgccgga gatgatgtcg tccatatgtt
    45121 tctggaacag cggtgccatg atctctttca gctgttctga cagcgcgtaa gcgcgcagtt
    45181 tcgccgggtt agagagacgg tccatcatca gggtgatgcc gccctgtttc agcgcttcgg
    45241 tgatggtttc ccaaccgaac tgaatcagtt tttcggcata tgccggatcg gtgccttctt
    45301 ccacgagctt gtcgaagcac agcagagagc cagcctgcaa cataccgcac aggatggttt
    45361 gctcgcccat caggtcagat ttcacttccg caacgaaaga ggattccagc acgcccgcac
    45421 gatgaccacc ggttgccgcc gcccacgctt tagcgatcgc catgccttcg cctttcggat
    45481 cgttttccgg gtgaacggca atcagcgtcg gtacgccgaa tccacgtttg tactcttcac
    45541 gcacttcggt gccagggcat ttcggcgcaa ccattactac ggtgatgtct ttacggatct
    45601 gctcgcctac ttccacgatg ttgaaaccat gcgagtaacc cagcgccgcg ccgtctttca
    45661 tcagtggctg tacggtgcgc actacatcag agtgctgctt gtccggcgtc aggttaacca
    45721 ccagatccgc ctgtgggatc agttcttcgt aagtacccac tttaaaacca ttttcggttg
    45781 ctttacgcca ggatgcgcgc ttctcagcaa tcgcttcttt acgcagagcg taggagatat
    45841 cgagaccaga atcacgcatg ttcaggccct ggttcagacc ctgtgcgcca cagccgacga
    45901 tgactacttt tttaccctga aggtagctcg cgccatcggc gaattcatcg cgccccataa
    45961 agcgacattt gcccaactgt gccagctgct ggcgcagatt cagtgtattg aagtagttag
    46021 ccatggtgat tcctcgtgat gttgtgcttc ttattgttcg gttcgcgttt gcgagattgg
    46081 attcactata tgacaggaaa tttattgcgg aaattgatat attcacaacg tcacattgca
    46141 atttctgcaa cgtcaacatt gagggctgcg ccattggatt tacgcgatct gaaaaccttc
    46201 ctgcatctgg cggaaagccg ccattttggc cgcagcgcac gagcgatgca cgtcagccca
    46261 tccacgctct cacggcagat tcaacgcctg gaagaagatc tcggtcagcc gctgtttata
    46321 cgcgataacc gcacggtgac actgacggaa gcaggcgaag aactgcgtgt tttcgcccag
    46381 caaacgttgt tgcagtatca gcaactgcgc cacaccatcg atcagcaagg accgtcgctc
    46441 tctggcgagc tgcatatttt ctgctcggtg accgccgcct acagccatct gccgccgatt
    46501 ctcgaccgct ttcgcgcgga acatccgtca gtggagatta aactcacgac tggtgatgcg
    46561 gcagatgcga tggaaaaggt cgtcactggc gaagcggatc tggcgattgc gggtaaaccg
    46621 gaaaccttgc ccggcgcagt ggcattttcg atgctggaga acctggcggt ggtgctgatc
    46681 gcacccacgt tgccctgccc ggtgcgtaat caggtctcgg tagagaagcc ggactggtca
    46741 acggtaccgt ttatcatggc cgatcagggg ccagtacgcc gccgtattga actgtggttt
    46801 cggcgtaaca aaattagtaa cccgatgatt tacgccacgg tcggcgggca tgaagcgatg
    46861 gtgtcgatgg tagcgctcgg ctgtggcgtg gccttgttgc cggaagtggt gctggaaaac
    46921 agcccggaac cagtgcgtaa ccgcgtgatg attttagagc gcagtgatga gaaaacgccg
    46981 tttgaactgg gcgtgtgtgt gcagaaaaag cggctacatg agccgctgat tgaggcgttc
    47041 tggaagattt tgccgaacca ctaacccgcc aaaaagaacc tgaacgccgg gttattggtt
    47101 tcgtcgtggc aatcgtagcc cagctcattc agccgggttt caaaatccgg ttcatgatcg
    47161 ccaagttcga acgccgccag tacgcgcccg tagtcggtac cgtggctgcg ataatggaac
    47221 agcgagatgt tccagtgcgt acccagcgtg ttgaggaagc gcagcagcgc gcccggtgat
    47281 tccgggaatt cgaagctgta gaggcgttcc tgcaacggat gtgatggacg cccgccaacc
    47341 atatagcgca catgtagctt cgccatttcg tcgtcggaga gatcaaccac gctgtagccg
    47401 ccgtcgttga gcatctgcaa aatttctttg cgctcttcga gaccgcggct caggcgcacg
    47461 ccgacaaaaa tgcaggcgtt tttggcatca gcaaagcggt agttgaactc ggtgaccgag
    47521 cgcccaccaa gtaactggca gaatttgagg aagctgccct tttcttccgg aatggtcacc
    47581 gccagtaacg cttcacgctg ttcgcccagt tcgcagcgtt ccgagacgta gcgcagaccg
    47641 tgaaagttca cgttggcacc ggaaagaata tgcgccagcc gttcaccgcg aatgttgtgc
    47701 tgggcgatgt attttttcat ccctgccagc gccagcgcgc cagagggttc agccaccgcg
    47761 cgtacatctt cgaacaggtc tttcatcgcc gcacagatgg catcgctatc gacggtgatg
    47821 atgtcgtcaa gatactcctg gcacaaacgg aaggtttcat cgccgatgcg ttttaccgcg
    47881 acgccttcag caaacagccc cacgcggggc agatcaacgg gatgacccgc atccagcgct
    47941 gctttcaggc aggcggagtc ttccgcttcc acggcgatca ctttgatttg cggcatcagc
    48001 tgtttgatca gcaccgctac gcctgccgcc agaccaccgc cgccgactgg cacaaatacg
    48061 cggtcgagat gggcgtcctg ctggagcagt tccagcgcca gcgtaccttg cccggcgatc
    48121 accatcggat gatcgaacgg cggcacccag gtgaacccct gctgctgtga cagttcgatc
    48181 gctttcgctt tcgcttcatc gaaatttgcg ccgtgaagca gcacttcgcc gccaaagccg
    48241 cgcaccgcat caactttgat atcggcggtg gcggttggca tgacgatcag cgccttcacg
    48301 cctaaccgtg cggaagaaaa cgcgacgccc tgcgcgtggt tacccgcaga agcggtgatc
    48361 acgccgtgcg ctttctgttc ttccgtcagg cccgccatca tggcgtatgc gccgcgcagc
    48421 ttaaagctat gaactggctg acggtcttcg cgtttcacca gaatcacgtt atcgagacgc
    48481 gacgagagtt tttccatttt ctgtagcggc gtgacctgcg ccgcttcgta gaccggcgca
    48541 cgcagcaccg ctcttaaata ttcggcaccc tcaggggcac cggacagggg ttgtgagtct
    48601 gccatcatta accccccagt ttcgatttat cgcgcaccgc gcctttgtcg gcgctggttg
    48661 ccaggctggc gtaggcgcgc agggcaaagg agacctgacg ttcacggttt ttcggcgtcc
    48721 aggctttgtc accccgagct tcctgcgctt cacgacgcgc cgccagttcg gcatcgctta
    48781 cctgtaactg aataccacgg ttcggaatgt cgatggcgat caggtcgccg tcttcaatca
    48841 ggccaatgct gccgccactt gccgcttccg gtgagacgtg gccgatggaa agaccagagg
    48901 tgccgccgga gaagcgtccg tcggtgatca gcgcgcaggc tttaccgaga cccattgatt
    48961 tcaggaagct ggttgggtag agcatttcct gcatccccgg accgcctttc gggccttcat
    49021 agcggatcac cactacatcg ccagcgacaa ctttgccgcc gagaatcgct tctaccgcgt
    49081 cgtcctggct ttcgtatact ttcgccgggc cggtgaattt gaggatgctg tcatcgacgc
    49141 ccgcggtttt aacgatgcag ccgttttccg caaagttacc gtagagcacc gccaggccgc
    49201 cgtctttgct gtaggcgtgt tccagcgagc ggatacagcc attggcgcga tcgtcatcga
    49261 gagaatccca acggcaatcc tgcgagaatg cctgtgtagt acgaatgcca gcagggcctg
    49321 cgcggaacat attttttacc gcgtcatcct gggtcagcat aacgtcgtat tgttccagcg
    49381 tttgtggcaa cgtcaggcca agcacgtttt tcacatcacg gttcagtaac cccgcgcgat
    49441 ccagttcgcc gagaataccg ataacaccac cagcacgatg aacatcttcc atatggtatt
    49501 tctgggtgct cggcgcaact ttgcataact gcgggacttt acgcgaaagt ttgtcgatat
    49561 cactcatggt gaagtcgatt tccgcttcct gcgccgccgc cagcaggtga agtacagtgt
    49621 tagtcgatcc acccatcgcg atatccagcg tcatggcgtt ttcaaacgcc gccttactgg
    49681 cgatattacg cggcagtgca ctttcgtcat tttgctcgta gtaacgtttg gtcaattcaa
    49741 caatgcgttt accggcattg aggaacagct gcttacggtc ggcgtgagtt gccagcagcg
    49801 agccgttgcc cggctgcgac aggcccagcg cttcggtcag gcagttcatt gagttagcgg
    49861 taaacatccc ggagcaggaa ccgcaggttg ggcatgcgga acgttcaacc tgatcgcttt
    49921 gggagtcaga aactttcggg tctgccccct ggatcatcgc atcaaccaga tcgagcttga
    49981 tgatctgatc ggacagtttg gttttcccgg cctccatcgg gccgccggaa acaaagatca
    50041 ccggaatatt caggcgcagg gaagccatca gcatccccgg ggtgattttg tcgcagttag
    50101 agatgcagac catggcatcg gcgcagtggg cattgaccat atactcaacg gaatcagcga
    50161 tcagctcgcg agatggcagt gaataaagca tgcccccgtg gcccatagcg atcccatcat
    50221 ccaccgcaat ggtattgaac tctttggcaa cgccgccagc cgcttcaatt tgttcggcga
    50281 ccagtttacc gagatcgcgc agatgaacgt gacccggtac aaattgggtg aacgagttca
    50341 caaccgcgat aatcggctta ccgaaatcgg cgtcggtcat tccggtggcg cgccacagcg
    50401 cacgagcacc cgccatatta cgaccatgag tggtggtggc ggaacggtac ttaggcatac
    50461 tttatttact cccagtgtct gtctcgtaaa tgggacggtg cgtgccgtcc cattttttgt
    50521 atttattgat taacttgatc taaccagccc catttatctt cagtttcacc agtgaagagg
    50581 ccgaagaagg cttgctggat gcgtttggta accgggccgc aacggccttc acctacctga
    50641 ataccgtcta cactgcgcac tggcgtgatt tctgccgctg tcccagacat aaacacttca
    50701 tccgccaggt acagtgattc gcgcgacagc acctgctcac gcacttcaat tcccagctct
    50761 ttcgccagtt tgatgatggc atcacgggta atacccggca gcgcggatga ggtgaacggt
    50821 ggggtgaaca gcacgccatc tttcacttca aacaggtttt cgcccgcacc ttcagagata
    50881 taaccgttca catccaacgc gataccttcc tgataaccgt ggcggcgcgc ttcgctaccc
    50941 accagcaggg aagagaggta gttaccaccg gcttttgccg ccgtcgggat ggtgtttggt
    51001 gctgcgcggt tccaggagga aaccatcgca tcgatcccct gctccagcgc ttctgcgccc
    51061 agatacgctc cccacgggaa agcggcgata atcacgtcgg ttgagtatcc cgctggcggg
    51121 tttacgccca tgccaacatc accaacgaag atcagcggac ggatataggc gctggtgaga
    51181 ttgtttttgc ggatcacgtc acgacaagct tccatcagct catcaatgct ctgcgaaacc
    51241 gggaagcgat agattttggc ggagtcatgc agacgctgca tatgctcacg atggcggaat
    51301 acaaccggtc ctttgtgcga gtcgtagcaa cggatgcctt caaaaaccga ggtgccatag
    51361 tgcagcgcgt gcgacatcac atgcaccttc gcgtcttccc agcgaaccat ctccccattg
    51421 aaccaaatgt aatcagcttt cttcgtggtc atttttatat tccttttgcg ctcaggcgcg
    51481 gatttgttgt gatgtggttg tgctctggca gatggcaacg tgtgcgacgt ccaccagttt
    51541 atttaactga ctaaacagta agtcgaccga ccgtgggctg gcaacggtca attcgatatt
    51601 tatattttgt gcatcgctgg cggcggccat attcattgag cagacgtgga aaccacgatg
    51661 acgcaccacg cgtaaaacac gttctaaggt ttccggattg aagcgagccg atacattgac
    51721 ctgatgttgc atcatgataa tttctccaac atttcagaat tactggcacc aggcggcacc
    51781 agcggccaga cgttctcaag ttcgtcgatt gagacatgaa gcaggtatgg cccatcactg
    51841 ttcagcatgg tgtcgagtgc cgcttcaacc tggtctttat gggtgatgtg ttggccaggg
    51901 atgccgaagg cgctggctaa catgaggaaa tcggggttat cggtaagggt tgtttcgctg
    51961 tatcgttcct ggaaaaacag ttgctgccat tgtcgaacca tccctaaccg ttggttatcg
    52021 agtaagacga ttttcaacgg taactgcttg cgttttacgg tgcccagctc ttgcacattc
    52081 atcatgaaag agccgtcacc ggagatacag acgacagtat cgttcggtcg cgcgacttgt
    52141 gcgccaaccg ccgccggtaa accgaaaccc atggtgccta agccgctgga ggtgatgaag
    52201 ttttccgggc gagtgtggac gatgtgctgg gcagcccaca tctggtgctg ccccacatct
    52261 gtggtcacga cgcaatccgc cggtttacga tccgacagtt gttttaacaa caacggcgcg
    52321 tagatagcgt caccaggatg gtcgtaacgc caggcatgtt catcacgcag ttgtgcgcag
    52381 tgttgctgcc agtcatcgat atttaacggc tgctgtaatg ctggtaacag agcatttaaa
    52441 tcaccctgta atgccgcatg tgcctgacgc agcttgttca tttctgccgg atcgatatcc
    52501 atatggataa cgctggcgtg tggtgcgaag gtgttcagtt tgccggtcac ccggtcatca
    52561 aaacgtgcgc ccacggctat cagtagatcg cactcctgaa ccgcgaagtt cgccgctttg
    52621 gtgccgtgca ttcccagcat gcccagatag tacggataat ccgcttcaac tgcgcccagc
    52681 cctttcagcg tgcaggtggc aggcattttt gtggtagcga gaaattcacg caaagccgaa
    52741 actgcctgcg ccatgcccac gccaccgcca acgtacagca tcggtttttg cgcttttgcc
    52801 agcatctgac gcgcttgctc gacttcggca tgggggaaag tcacttcgtt ttcaacggtg
    52861 gtgaaccacg gttccagatc gccgctggct aactggatat cttttggaat atcgaccaaa
    52921 accggaccag gacgaccaga gctggcgacg tcaaacgctt cggccatgat acgcggtaac
    52981 tcttccagtg attgcaccag gaaactgtgc ttggtgcagg ctaacgacaa ccccagaata
    53041 tccacctcct gaaatgcgtc agtgccgata aacggtgcgg acacttgacc ggtgatagca
    53101 acaacgggga tggaatctaa cagtgcgtcc gcaagcccgg ttatcaggtt ggttgcgccc
    53161 ggaccagacg tggcgataca tacgccagtt ttgccagtag cacgggcata accgatagcc
    53221 gccattgccg caccctgttc atgtcggcac agcaagtgct ccatgccgcc gtcatacaat
    53281 gcatcgtaaa ccggcataat tgcgccaccc ggataaccga aaacggtatt cacaccctgt
    53341 gcccgcaacg catgtaccac ccactgtgcg ccattcatag ttagttcccc gtcctgaatc
    53401 ttgagaaaca gaattttgtg ctgttattca ttgtctgctc cccggttatg tttttaaggt
    53461 caaaaaaaac ccccggacct ttcggtgcgg gggtcttagt tcgttaaggc ttgatctcta
    53521 agcctttcct cgtccaagtg cagccccgca cggtgggata ataatcacca ccacgctaat
    53581 cacgaccagg ctaatcactc gtagaagggc tgtcattttg tcttttcttg catcttgttc
    53641 gaaggaatgc ctaaagagtt accatagatt ttgcgaatag cacaagatat tttttggccg
    53701 atttttatga tgtctttaat aatttcaaga gaaattgttg ttttttaaaa agaaaatagt
    53761 gagtgaaaaa aattcaattt cagtatgaat gttgttccct tcctcgtagt tcatcctttg
    53821 cccgctgcat ttttgcgagc atcattccac cgccagaaca actcaacttc acttgcacaa
    53881 ataaacagga atcagccact aaaattcacg aattagcggg ctacagcagc gatatcttat
    53941 gcacataatg gtgactcaag gagggcttat gtcactgtca attgttcata cccgcgcagc
    54001 cctgggagta aatgcgcccc caatcactgt tgaggtacat atcagtaaag gtctaccagg
    54061 cttaacgatg gtgggcttac cagaaacaac ggtaaaagaa gctcgcgatc gcgtgcgcag
    54121 cgccattatc aatagcggat atgaatatcc ggcgaaaaaa atcaccatca accttgctcc
    54181 agccgatctg ccaaaagaag ggggacgata tgatttacct atcgccattg cgttgctggc
    54241 agcctcagaa cagcttacag ccaataagtt agatgaatat gaattagtcg gagaactggc
    54301 gcttacaggc gctctgcgtg gcgttcccgg cgcaatctcc agtgcaactg aagccattaa
    54361 gtcgggcaga aaaattatcg tcgcgaaaga taacgaggat gaagtggggc taattaacgg
    54421 tgaaggatgc ctgatagccg atcatctgca ggctgtctgt gcgtttctgg agggtaagca
    54481 cgctctcgaa cgcccgaaac caactgatgc agtatcccgg gcgctacaac atgatctcag
    54541 tgatgttgtc ggtcaggagc aaggaaagcg aggactggaa attaccgccg ctggcgggca
    54601 caacctttta ctgattggac cgccgggaac aggtaaaaca atgctcgcca gccgtattaa
    54661 tggccttttg ccagatttaa gcaatgaaga ggcactggag agcgctgcga tattaagtct
    54721 ggtaaatgct gaatcagtac aaaaacaatg gcggcagcgc ccgttccgct cacctcatca
    54781 cagtgcgtcg ttaactgcga tggtgggcgg tggtgcaatt ccagggccag gtgaaatttc
    54841 gctggcgcat aacggcgtgc tttttcttga tgagctacct gaatttgaac ggcgtacact
    54901 ggatgccttg cgagagccga ttgaatccgg gcagatccat ctttcacgca cacgagcaaa
    54961 aataacctat ccagcccgtt tccagcttgt cgcggcgatg aatcccagcc ctaccggaca
    55021 ttatcaggga aaccataacc gctgcacacc agaacagaca ttacgttatc tcaaccggct
    55081 ctcggggccc tttctcgacc gcttcgatct ctcactagag atcccattac cgcccccggc
    55141 attttgagta aaacggtagt gcagggagaa aacagcacca ccgttaaaca acgtgtaatg
    55201 gccgccagag agcgccaatt taagcggcag aataaactga acgcctggct ggataatccg
    55261 gaaatacgcc aattctgcaa gcttgagagc gaagatgcgc agtggctgga agaaacgctg
    55321 atccatctgg ggttatcgat tcgtgcctgg cagcggttat tgaaagttgc acgaaccatt
    55381 gctgatattg atcagtctga cattatcaca cgtcagcatt tgcaggaggc agttagctat
    55441 cgtgcgattg accgtttgct catccatctg caaaaactac tgacataaaa aaagggcatt
    55501 tcgccctttt tattaatcgt cagaatcggt gtagtcttca gcaccttcaa cctgcggttt
    55561 accgccggaa agggtgtgaa aacgttttgg acgcttgata cgcgtcatat acttggacca
    55621 cacgcgttct gcttctgtca ctggctcacg ttcgccacgg catactgcta cgaagagttt
    55681 ctcttcctcg gtaaccggct cgcgtttgcc aagatccaac tcattgaagg cataaccatg
    55741 acgctcaagc agttgtgcct ctttgatggt gaagtcacca tgacgagaga atccacgtgg
    55801 ataatgttta ttgtcgaaat atcgattagt cgtcgtaaag ctttccgcca tcctgcacgc
    55861 tcctaattct ttgaccgagc tagttatggc gcggagtatt agttacgctt gacagagtgt
    55921 aaaacaaaac atttaaatca taacgacaaa taattttgcg gagagcactg tggatacgga
    55981 attgttaaaa actttcctgg aagttagccg aacgcgtcac tttggtcgag cggctgaatc
    56041 gctctatctg acccaatcag ccgtgagctt tcgaatcaga caactggaaa atcaactggg
    56101 tgtgaatctt ttcacccgcc acagaaacaa tatccgttta accgctgccg gtgaaaaact
    56161 actgccttat gcagaaacgc tcatgagcac ctggcaggcc gcccgtaagg aggtggcgca
    56221 tacctcacga cataacgagt tttctatcgg tgccagcgcc tcattgtggg aatgtatgct
    56281 taatcagtgg ctgggacgct tgtatcaaaa tcaagatgcc catacaggct tacagttcga
    56341 agcgcgaatt gcccaacgac agtctctggt aaaacagctg catgaacgcc agcttgatct
    56401 tcttattacc actgaagcgc ccaaaatgga cgaatttagt agtcagttgc tggggtattt
    56461 cactttagcg ctttatacca gtgccccttc taaactaaag ggagatctta actatctgcg
    56521 actggagtgg gggccagatt ttcaacagca tgaggcaggt ttgatcggtg ctgacgaagt
    56581 tcccattctg acaaccagtt ctgctgaact ggcacagcaa cagattgcga tgcttaatgg
    56641 ttgcacctgg ctacccgtca gttgggcgcg taaaaagggc ggcctgcata ccgttgtcga
    56701 tagcacaaca ctttcacggc cgctttatgc catatggctg caaaatagcg ataaaaatgc
    56761 gttgattcgc gatctattga aaattaacgt gctggatgaa gtgtattaat ctgaatggct
    56821 ggcaaggatg ccggtagaag gatttacttc ggagaggtta tttcagataa aaaaaatcct
    56881 tagctttcgc taaggatgat ttctggcagg ggcggagaga ctcgaactcc caacacccgg
    56941 ttttggagac cggtgctcta ccaattgaac tacgccccta attagggtgg cggaacggac
    57001 gggactcgaa cccgcgaccc cctgcgtgac aggcaggtat tctaaccgac tgaactaccg
    57061 ctccaccgaa ttcttttaca accaccggtt ttatgaccgg ctt
//
LOCUS       DADXDL010000018        56573 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.018, whole genome shotgun sequence.
ACCESSION   DADXDL010000018 DADXDL010000000
VERSION     DADXDL010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 56573)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56573)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56573
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.018"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(75..1739)
                     /gene="glnS"
                     /locus_tag="IRB70_001401"
     CDS             complement(75..1739)
                     /gene="glnS"
                     /locus_tag="IRB70_001401"
                     /EC_number="6.1.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--tRNA ligase"
                     /protein_id="HBC0631333.1"
                     /translation="MSEAEARPTNFIRQIIDEDLASGKHTTVHTRFPPEPNGYLHIGH
                     AKSICLNFGIAQDYKGQCNLRFDDTNPVKEDIEYVESIKNDVEWLGFHWSGNVRYSSD
                     YFDQLHAYAIELINKGLAYVDELTPEQIREYRGTLTQPGKNSPYRDRSVEENLALFEK
                     MRTGGFEEGKACLRAKIDMASPFIVMRDPVLYRIKFAEHHQTGNKWCIYPMYDFTHCI
                     SDALEGITHSLCTLEFQDNRRLYDWVLDNITIPVHPRQYEFSRLNLEYTVMSKRKLNL
                     LVTDKHVEGWDDPRMPTISGLRRRGYTAASIREFCKRIGVTKQDNTIEMASLESCIRE
                     DLNENAPRAMAVIDPVKLVIENYQGEGEMVTMPNHPNKPEMGSRQVPFSGEIWIDRAD
                     FREEANKQYKRLVLGKEVRLRNAYVIKAERVEKDAEGNITTIFCTYDADTLSKDPADG
                     RKVKGVIHWVSAAHALPVEIRLYDRLFSVPNPGAADDFLSVINPESLVIKQGFAEPSL
                     KDAVAGKAFQFEREGYFCLDSRHSTAEKPVFNRTVGLRDTWAKVGE"
     gene            complement(1942..3888)
                     /gene="nagE"
                     /locus_tag="IRB70_001402"
     CDS             complement(1942..3888)
                     /gene="nagE"
                     /locus_tag="IRB70_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetyl glucosamine transporter subunit
                     IIABC"
                     /protein_id="HBC0631334.1"
                     /translation="MNILGFFQRLGRALQLPIAVLPVAALLLRFGQPDLLNVAFIAQA
                     GGAIFDNLALIFAIGVASSWSKDSAGAAALAGAVGYFVLTKAMVTINPEINMGVLAGI
                     ITGLVGGAAYNRWSDIKLPDFLSFFGGKRFVPIATGFFCLVLAAIFGYVWPPVQHAIH
                     AGGEWIVSAGALGSGIFGFINRLLIPTGLHQVLNTIAWFQIGEFTNAAGTVFHGDINR
                     FYAGDGTAGMFMSGFFPIMMFGLPGAALAMYFAAPKERRPMVGGMLLSVAVTAFLTGV
                     TEPLEFLFMFLAPLLYLLHALLTGISLFVATLLGIHAGFSFSAGAIDYALMYNLPAAS
                     QNVWMLLVMGVVFFAIYFVVFSLVIRMFNLKTPGREDKEDEIVTEEANSNTEEGLNQL
                     ATNYIAAVGGTDNLKAIDACITRLRLTVADSARVNDTMCKRLGASGVVKLNKQTIQVI
                     VGAKAESIGDAMKKVVARGPVAAASAETAPATAAPVAKPQAVPNAVSVAELVSPITGD
                     VVALDQVPDEAFASKAVGDGVAVKPTDKIVVSPAAGTIVKIFNTNHAFCLETEKGAEI
                     VVHMGIDTVALEGKGFKRLVEEGAQVSAGQPILEMDLDYLNENARSMISPVVCSNIDD
                     FSGLIIKAQGHVVAGQTPLYEIKK"
     gene            4221..5021
                     /gene="nagB"
                     /locus_tag="IRB70_001403"
     CDS             4221..5021
                     /gene="nagB"
                     /locus_tag="IRB70_001403"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008805656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBC0631335.1"
                     /translation="MRLIPLTTAEQVGKWAARHIVNRINAFKPTADRPFVLGLPTGGT
                     PMTTYKALVEMHKAGQVSFKHVVTFNMDEYVGLPKEHPESYYSFMHRNFFDHVDIPAE
                     NINLLNGNAPDIDAECRQYEEKIRSYGKIHLFMGGVGNDGHIAFNEPASSLASRTRIK
                     TLTHDTRVANSRFFDNDVNQVPKYALTVGVGTLLDAEEVMILVLGSQKALALQAAVEG
                     CVNHMWTISCLQLHPKAIMVCDEPSTMELKVKTLRYFNELEAENIKGL"
     gene            5081..6229
                     /gene="nagA"
                     /locus_tag="IRB70_001404"
     CDS             5081..6229
                     /gene="nagA"
                     /locus_tag="IRB70_001404"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBC0631336.1"
                     /translation="MYALTQGRIFTGHEFLDDHAVVIADGLIKSVCPVAELPPEIEQR
                     SLNGAILSPGFIDVQLNGCGGVQFNDTAEAVSVETLEIMQKANEKSGCTNYLPTLITT
                     SDELMKQGVRVMREYLAKHPNQALGLHLEGPWLNLVKKGTHNPNFVRKPDAALVDFLC
                     ENADVITKVTLAPEMVPAEVISKLANAGIVVSAGHSNATLKEAKAGFRAGITFATHLY
                     NAMPYITGREPGLAGAILDEADIYCGIIADGLHVDYANIRNAKRLKGDKLCLVTDATA
                     PAGANIEQFIFAGKTIYYRNGLCVDENGTLSGSSLTMIEGVRNLVEHCGIALDEVLRM
                     ATLYPARAIGVEKRLGTLAAGKVANLTAFTPDFKITRTIVNGNEVVTQ"
     gene            6238..7458
                     /gene="nagC"
                     /locus_tag="IRB70_001405"
                     /gene_synonym="nagR"
     CDS             6238..7458
                     /gene="nagC"
                     /locus_tag="IRB70_001405"
                     /gene_synonym="nagR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator NagC"
                     /protein_id="HBC0631337.1"
                     /translation="MTPGGQAQIGNVDLVKQLNSAAVYRLIDQYGPISRIQIAEQSQL
                     APASVTKITRQLIERGLIKEVDQQASTGGRRAISIVTETRNFHAIGVRLGRHDATITL
                     FDLSSKVLAEEHYPLPERTQQTLEHALLNAIAQFIDSYQRKLRELIAISVILPGLVDP
                     DSGKIHYMPHIQVENWGLVEALEERFKVTCFVGHDIRSLALAEHYFGASQDCEDSILV
                     RVHRGTGAGIISNGRIFIGRNGNVGEIGHIQVEPLGERCHCGNFGCLETIAANAAIEQ
                     RVLNLLKQGYQSRVPLDDCTIKTICKAANKGDSLASEVIEYVGRHLGKTIAIAINLFN
                     PQKIVIAGEITEADKVLLPAIESCINTQALKAFRTNLPVVRSELDHRSAIGAFALVKR
                     AMLNGILLQHLLEN"
     gene            7506..8258
                     /gene="nagD"
                     /locus_tag="IRB70_001406"
     CDS             7506..8258
                     /gene="nagD"
                     /locus_tag="IRB70_001406"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide monophosphatase NagD"
                     /protein_id="HBC0631338.1"
                     /translation="MTIKNVICDIDGVLMHDNVAVPGAAEFLHGIMDKGLPLVLLTNY
                     PSQTGQDLANRFATAGVDVPDSVFYTSAMATADFLRRQEGKKAYVVGEGALIHELYKA
                     GFTITDVNPDFVIVGETRSYNWDMMHKAAYFVANGARFIATNPDTHGRGFYPACGALC
                     AGIEKISGRKPFYVGKPSPWIIRAALNKMQAHSEETVIVGDNLRTDILAGFQAGLETI
                     LVLSGVSSLDDIDSMPFRPSWIYPSVAEIDVI"
     gene            8514..10178
                     /gene="asnB"
                     /locus_tag="IRB70_001407"
     CDS             8514..10178
                     /gene="asnB"
                     /locus_tag="IRB70_001407"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001724523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase B"
                     /protein_id="HBC0631339.1"
                     /translation="MCSIFGVFDIKTDAVELRKKALELSRLMRHRGPDWSGIYASDNA
                     ILAHERLSIVDVNAGAQPLYNQQKTHVLAVNGEIYNHQALRAEYGDRYQFQTGSDCEV
                     ILALYQEKGPEFLDDLQGMFAFALYDSEKDAYLIGRDHLGIIPLYMGYDEHGQLYVAS
                     EMKALVPVCRTIKEFPAGSYLWSQDGEIRSYYHRDWFDYDAVKDNVTDKNELRQALED
                     SVKSHLMSDVPYGVLLSGGLDSSIISAITKKYAARRVEDQERSEAWWPQLHSFAVGLP
                     GSPDLKAAQEVANHLGTVHHEIHFTVQEGLDAIRDVIYHIETYDVTTIRASTPMYLMS
                     RKIKAMGIKMVLSGEGSDEVFGGYLYFHKAPNAKELHEETVRKLLALHMYDCARANKA
                     MSAWGVEARVPFLDKKFLDVAMRINPQDKMCGNGKMEKHILRECFEAYLPASVAWRQK
                     EQFSDGVGYSWIDTLKEVAAQQVSDQQLETARFRFPYNTPTSKEAYLYREIFEELFPL
                     PSAAECVPGGPSVACSSAKAIEWDEAFKKMDDPSGRAVGVHQSAYK"
     gene            complement(10220..10657)
                     /locus_tag="IRB70_001408"
     CDS             complement(10220..10657)
                     /locus_tag="IRB70_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000943401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631340.1"
                     /translation="MLRFMTALMGALLLMQSAFADTVKPEIGKYVFGYRGQEGAVVWM
                     MRIGPKASNEALIQVSHVDNDIDGQIFRCKVKALQEGEKSYTAVIKGKSFELLRLKEG
                     NGSLHIPDEQATWSVAYSDELSNSDVANPEHFLTAYQNQQAPQ"
     gene            10990..11066
                     /locus_tag="IRB70_001409"
     tRNA            10990..11066
                     /locus_tag="IRB70_001409"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11024..11026,aa:Met,seq:cat)
     gene            11075..11159
                     /locus_tag="IRB70_001410"
     tRNA            11075..11159
                     /locus_tag="IRB70_001410"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11109..11111,aa:Leu,seq:tag)
     gene            11183..11257
                     /locus_tag="IRB70_001411"
     tRNA            11183..11257
                     /locus_tag="IRB70_001411"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11215..11217,aa:Gln,seq:ttg)
     gene            11273..11349
                     /locus_tag="IRB70_001412"
     tRNA            11273..11349
                     /locus_tag="IRB70_001412"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11307..11309,aa:Met,seq:cat)
     gene            11398..11472
                     /locus_tag="IRB70_001413"
     tRNA            11398..11472
                     /locus_tag="IRB70_001413"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:11430..11432,aa:Gln,seq:ctg)
     gene            complement(11626..12801)
                     /gene="ubiF"
                     /locus_tag="IRB70_001414"
     CDS             complement(11626..12801)
                     /gene="ubiF"
                     /locus_tag="IRB70_001414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol
                     hydroxylase"
                     /protein_id="HBC0631341.1"
                     /translation="MTNQPTEIAIVGGGMVGGALALGLAQHGFAVTVIEHAEPAPFVA
                     DSQPDVRISAISAASVSLLKGLGIWDAVQAMRCHPYRRLETWEWETAHVVFDAAELKL
                     PLLGYMVENTVLQQALWQALEAHPKVTLRVPGSLIALHRDNDLQELELKGGEVIQAKL
                     VIGADGANSQVRQMAGIGVHAWQYAQSCMLISVQCENDPGDSTWQQFTPDGPRAFLPL
                     FDNWASLVWYDSPARIRQLQNMNMAQLQAEIAKHFPSRLGYVTPLAAGAFPLTRRHAL
                     QYVQPGLTLVGDAAHTIHPLAGQGVNLGYRDVDALIDVLVNARSYGEAWASYPVLKRY
                     QMRRMADNFIMQSGMDLFYAGFSNNLPPLRFMRNLGLMAAERAGVLKRQALKYALGL"
     gene            12947..14371
                     /gene="miaB"
                     /locus_tag="IRB70_001415"
     CDS             12947..14371
                     /gene="miaB"
                     /locus_tag="IRB70_001415"
                     /EC_number="2.8.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (N6-isopentenyl
                     adenosine(37)-C2)-methylthiotransferase MiaB"
                     /protein_id="HBC0631342.1"
                     /translation="MTKKLHIKTWGCQMNEYDSSKMADLLDATHGYQLTDVAEEADVL
                     LLNTCSIREKAQEKVFHQLGRWKLLKEKNPDLIIGVGGCVASQEGEHIRQRAHYVDII
                     FGPQTLHRLPEMINSVRGDRSPVVDISFPEIEKFDRLPEPRAEGPTAFVSIMEGCNKY
                     CTYCVVPYTRGEEVSRPSDDILFEIAQLAAQGVREVNLLGQNVNAWRGENYDGTTGSF
                     ADLLRLVAAIDGIDRIRFTTSHPIEFTDDIIEVYRDTPELVSFLHLPVQSGSDRILNL
                     MGRTHTALEYKAIIRKLRAARPDIQISSDFIVGFPGETTEDFEKTMKLIADVNFDMSY
                     SFIFSARPGTPAADMVDDVPEEEKKQRLYILQERINQQAMAWSRRMLGTTQRILVEGT
                     SRKSIMELSGRTENNRVVNFEGTPDMIGKFVDVEITDVYPNSLRGKVVRTEDEMGLRV
                     AETPESVIARTRKENDLGVGYYQP"
     gene            14524..15564
                     /locus_tag="IRB70_001416"
     CDS             14524..15564
                     /locus_tag="IRB70_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415193.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBC0631343.1"
                     /translation="MNIDTREITLEPADNARLLSLCGPFDDNIKQLERRLGIEINRRD
                     NHFKLTGRPICVTAAADILRSLYVDTAPMRGQIQDIEPEQIHLAIKEARVLEQSAESV
                     PEYGKAVNIKTKRGVIKPRTPNQAQYIANILDHDITFGVGPAGTGKTYLAVAAAVDAL
                     ERQEIRRILLTRPAVEAGEKLGFLPGDLSQKVDPYLRPLYDALFEMLGFEKVEKLIER
                     NVIEVAPLAYMRGRTLNDAFIILDESQNTTIEQMKMFLTRIGFNSKAVITGDVTQIDL
                     PRNTKSGLRHAIEVLADVEEISFNFFHSEDVVRHPVVARIVNAYEAWEEAEQKRKAAL
                     AAERKREEQEQK"
     gene            15561..16028
                     /gene="ybeY"
                     /locus_tag="IRB70_001417"
     CDS             15561..16028
                     /gene="ybeY"
                     /locus_tag="IRB70_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014169133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBC0631344.1"
                     /translation="MSQVILDLQLACEDNSGLPEESQFQTWLNAVIPQFQEESEVTIR
                     VVDTAESHSLNLTYRGKDKPTNVLSFPFEVPPGMEMSLLGDLVICRQVVEKEAQEQGK
                     PLEAHWAHMVVHGSLHLLGYDHIEDDEAEEMEALETEIMLALGYEDPYIAEKE"
     gene            16118..16996
                     /gene="corC"
                     /locus_tag="IRB70_001418"
     CDS             16118..16996
                     /gene="corC"
                     /locus_tag="IRB70_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308723.1"
                     /note="CorC(YbeX) belongs to the Cyclin M Mg2+ Exporter
                     (CNNM) family, and was characterized as belonging to a set
                     of three proteins, at least one of which must be present
                     for CorA to function; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family magnesium/cobalt transport protein
                     CorC"
                     /protein_id="HBC0631345.1"
                     /translation="MSDDNSHSSDTISNKKGFFSLLLSQLFHGEPKNRDELLALIRDS
                     GQNDLIDEDTRDMLEGVMDIADQRVRDIMIPRSQMITLKRNQTLDECLDVIIESAHSR
                     FPVISEDKDHIEGILMAKDLLPFMRSDAEAFSMDKVLRQAVVVPESKRVDRMLKEFRS
                     QRYHMAIVIDEFGGVSGLVTIEDILELIVGEIEDEYDEEDDIDFRQLSRHTWTVRALA
                     SIEDFNEAFGTHFSDEEVDTIGGLVMQAFGHLPARGETIDIDGYQFKVAMADSRRIIQ
                     VHVKIPDDSPQPKLDE"
     gene            17021..18562
                     /gene="lnt"
                     /locus_tag="IRB70_001419"
     CDS             17021..18562
                     /gene="lnt"
                     /locus_tag="IRB70_001419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="apolipoprotein N-acyltransferase"
                     /protein_id="HBC0631346.1"
                     /translation="MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIISLMGL
                     QALTFNRRPLQSAAIGFCWGFGLFGSGINWVYVSIATFGGMPGPVNIFLVVLLAAYLS
                     LYTGLFAGVLSRLWPKTTWLRVAIAAPALWQVTEFLRGWVLTGFPWLQFGYSQIDGPL
                     KGLAPLMGVEAINFLLMMVSGLLALALVKRNWRPLVVAVVLFALPFPLRYIQWFTPQP
                     EKTIQVSMVQGDIPQSLKWDEGQLLNTLKIYYNATAPLMGKSSLIIWPESAITDLEIN
                     QQPFLKALDGELRDKGSSLVTGIVDARLNKQNRYDTYNTIITLGKGAPYSYESADRYN
                     KNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPPLSVNGIELTAAICYEIIL
                     GEQVRDNFRPDTDYLLTISNDAWFGKSIGPWQHFQMARMRALELARPLLRSTNNGITA
                     VIGPQGEIQAMIPQFTREVLTTNVTPTTGLTPYARTGNWPLWVLTALFGFAAVLMSLR
                     QRRKR"
     gene            complement(18695..20572)
                     /locus_tag="IRB70_001420"
     CDS             complement(18695..20572)
                     /locus_tag="IRB70_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001276742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBC0631347.1"
                     /translation="MSASSVKPLNVQLPAITLILFALCVGIFCYLAQWMSYEEVDQSA
                     LIHLGANVASLTLSGEPWRLFSSVFLHSSFSHLLMNMFALLVVGAVAERILGKWRLLI
                     VWLFSGVFGGLISACYALRESEQIVISVGASGAIMGIAGAAIATQLASGAGTHHKNQR
                     RVFPLLGMVALTLLYGARQTGIDNACHIGGLIAGGALGWLSARLVGQNRFVTEGGIIV
                     AVTLLLTGAIWLVQQQIDESVLQVRQSLREAFYPQEIEQERRQKKQQLVEERNALTET
                     LSAPVSREQASGDLLAEIADIHDMAINRDGNTLYAAIENTNSIVVFDLGQKKILHTFT
                     APIAKEKSLKHCGGCKDQGVRSLALSPDETLLYATSFEANALSVINVATGEIIQSITT
                     GAHPDSLILSRDGTKAWVMNRTSNSVSAIDLVTYQHVADIPLEKYDGTGTSGKPGAWV
                     MALSPDEKTLLIPGMVRGDIVRINTITHQKVDFPTGDARGVVSAMGFRPKNGEIIFAD
                     SQGISRISVGDQQASIMTQWCSRSVYSVEGISPDGQYLALVSYGLQGYVILLNINAGQ
                     IIGVYPASYVNHLRFSADGRKIFVMAKNGLIQMDRTRSLDPQAIIRHPQYGDVACIPE
                     P"
     gene            21026..21934
                     /gene="gltI"
                     /locus_tag="IRB70_001421"
     CDS             21026..21934
                     /gene="gltI"
                     /locus_tag="IRB70_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter
                     substrate-binding protein GltI"
                     /protein_id="HBC0631348.1"
                     /translation="MQLRKPATAILALALSAGLAQADDAAPAAGSTLDKIAKNGVIVV
                     GHRESSVPFSYYDNQQKVVGYSQDYSNAIVEAVKKKLNKPDLQVKLIPITSQNRIPLL
                     QNGTFDFECGSTTNNVERQKQAAFSDTIFVVGTRLLTKKGGDIKDFADLKDKAVVVTS
                     GTTSEVLLNKLNEEQKMNMRIISAKDHGDSFRTLESGRAVAFMMDDALLAGERAKAKK
                     PDNWEIVGKPQSQEAYGCMLRKDDPQFKKLMDDTIAQVQTSGEAEKWFDKWFKNPIPP
                     KNLNMNFELSDEMKALFKEPNDKALN"
     gene            22104..22844
                     /gene="gltJ"
                     /locus_tag="IRB70_001422"
     CDS             22104..22844
                     /gene="gltJ"
                     /locus_tag="IRB70_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltJ"
                     /protein_id="HBC0631349.1"
                     /translation="MSIDWNWGIFLQQAPFGNTTYLGWIWSGFQVTIALSICAWIIAF
                     LVGSFFGILRTVPNRFLSGLGTLYVELFRNVPLIVQFFTWYLVIPELLPEKIGMWFKA
                     ELDPNIQFFLSSMLCLGLFTAARVCEQVRAAIQSLPRGQKNAALAMGLTLPQAYRYVL
                     LPNAYRVIVPPMTSEMMNLVKNSAIASTIGLVDMAAQAGKLLDYSAHAWESFTAITLA
                     YVLINAFIMLVMTLVERKVRLPGNMGGK"
     gene            22844..23518
                     /gene="gltK"
                     /locus_tag="IRB70_001423"
     CDS             22844..23518
                     /gene="gltK"
                     /locus_tag="IRB70_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter permease
                     GltK"
                     /protein_id="HBC0631350.1"
                     /translation="MYEFDWSSIVPSLPYLLDGLVITLKITVTAVVIGILWGTMLAVM
                     RLSSFAPVAWFAKAYVNVFRSIPLVMVLLWFYLIVPGFLQNVLGLSPKNDIRLISAMV
                     AFSMFEAAYYSEIIRAGIQSISRGQSSAALALGMTHWQSMKLIILPQAFRAMVPLLLT
                     QGIVLFQDTSLVYVLSLADFFRTASTIGERDGTQVEMILFAGFVYFVISLSASLLVSY
                     LKRRTA"
     gene            23518..24243
                     /gene="gltL"
                     /locus_tag="IRB70_001424"
     CDS             23518..24243
                     /gene="gltL"
                     /locus_tag="IRB70_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate ABC transporter ATP binding
                     protein GltL"
                     /protein_id="HBC0631351.1"
                     /translation="MITLKNVSKWYGHFQVLTDCSTEVKKGEVVVVCGPSGSGKSTLI
                     KTVNGLEPVQQGEITVDGIVVNDKKTDLAKLRSRVGMVFQHFELFPHLSIIENLTLAQ
                     VKVLKRDKAPAREKALKLLERVGLSAHANKFPAQLSGGQQQRVAIARALCMDPIAMLF
                     DEPTSALDPEMINEVLDVMVELANEGMTMMVVTHEMGFARKVANRVIFMDEGKIVEDS
                     PKDAFFDDPKSDRAKDFLAKILH"
     gene            24361..25296
                     /gene="rihA"
                     /locus_tag="IRB70_001425"
     CDS             24361..25296
                     /gene="rihA"
                     /locus_tag="IRB70_001425"
                     /EC_number="3.2.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-specific ribonucleoside hydrolase
                     RihA"
                     /protein_id="HBC0631352.1"
                     /translation="MALPILLDCDPGHDDAIAIVLALASPELDVKAITSSAGNQTPEK
                     TLRNVLRMLTLLNRTDIPVASGAVKPLMRDLIIADNVHGESGLDGPALPEPTFAPQNC
                     TAVELMAKTLRESAEPVTIVSTGPQTNVALLLNSHPELHSKIARIVIMGGAMGLGNWT
                     PAAEFNIYVDPEAAEIVFQSGIPVVMAGLDVTHKAQIHVEDTERFRAIGNPVSTIVAE
                     LLDFFLEYHKDEKWGFVGAPLHDPCTIAWLLKPELFTTVERWVGVETQGKYTQGMTVV
                     DYYYLTGNKPNATVMVDVDRQGFVDLLADRLKFYA"
     gene            25380..27050
                     /gene="hscC"
                     /locus_tag="IRB70_001426"
     CDS             25380..27050
                     /gene="hscC"
                     /locus_tag="IRB70_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone HscC"
                     /protein_id="HBC0631353.1"
                     /translation="MDNAELAIGIDLGTTNSLIAVWKDGAAQLIPNKFGEYLTPSIIS
                     MDENNHILVGKPAVSRRTSHPDKTAALFKRAMGSNTNWRLGSDTFNAPELSSLVLRSL
                     KEDAEEFLQRPIKDVVISVPAYFSDEQRKHTRLAAELAGLNAVRLINEPTAAAMAYGL
                     HTQQNTRSLVFDLGGGTFDVTVLEYATPVIEVHASAGDNFLGGEDFTHMLVDEVLKRA
                     AVAKNMLNESELAALYTSVEAAKCSNQLPLQISWQCQEETRECEFYENELEDLWLPLL
                     NRLRVPIEQALRDARLKPSQIDSLVLVGGASQMPLVQRIAVRLFGKLPYQSYDPSTIV
                     ALGAAIQAACRLRSEDIEEVILTDICPYSLGVEVNRQGVSGIFSPIIERNTTVPVSRV
                     ETYSTMHREQDSITVNVYQGENHKVKNNILVESFDVPLKKTGAYQSIDIRFSYDINGL
                     LEVDVLLEDGSVKSRVINHSPVTLSAQQIEESRTRLSALKIYPRDMLINRTFKAKLEE
                     LWARALGDEREEIGRVITDFDAALQSNDMARVDEVRRRASDYLAIEIP"
     gene            complement(27110..28561)
                     /gene="djlC"
                     /locus_tag="IRB70_001427"
     CDS             complement(27110..28561)
                     /gene="djlC"
                     /locus_tag="IRB70_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlC"
                     /protein_id="HBC0631354.1"
                     /translation="MKTCWQILEIESTTQIDIIRQAYLVRLPLCHPETDPQGFKALRQ
                     AYEEALRLAVNPVEEADDEEKDAAAEHEILRAFRALLDSESDRFQPSAWQKFIQQLNT
                     WNMEDVDQLRWPLCAVAIEARYLSLNCASLLAERLNWHSFNDSEGMDEEEREAFLEAI
                     QAGDCFDFLSLLEYPVALQNQTVEYYFALERCCRYHPDYVTAFMAMEGPWFIPDDVKL
                     HRKLLRWYSSVKTGMAELIPVAQQWQAENPESEDARYYQCAQRLYCGEGESLLADLCA
                     YRESYPSTQADNLLLQWSKRHCPDYFALLVMVIEARSMIDAQGQPLKYVPGESARTRL
                     LWAEILHSGKLSPLGQSFIESLFFKRKAWAWWKSRVGSETEQDSPLLDLYRVAEQVVL
                     EAFPKQEMLARLNTRLEGGDAHPLEAIITRMLLTKVKLEPEDEDVDEPTPENHEEKND
                     EDEKPQSITSIIKISLTVLVIGYALGKIAMLFS"
     gene            complement(28558..29265)
                     /locus_tag="IRB70_001428"
     CDS             complement(28558..29265)
                     /locus_tag="IRB70_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HBC0631355.1"
                     /translation="MNKEEQYLLFALSTPMEILNQGCKPAHDSPKMYTGIKEFDLSSS
                     WGINNRDDLIQTIYQMTDDGHANDLAGLYLTWHRSSPEEWKALNAGGSERGLIYTQFV
                     AQTAMCCGEGGIKAWDYVRMGFLSRVGVLNKWLTEDESLWLQSRVYIRAHHYYHSWMH
                     YFSAYSLGRLYWQSSQCEDNASLREALTLYKYDSAGSRMFEELAAGSDRFYATLPWQP
                     LTVQPECPVTLKDVSDL"
     gene            29367..29921
                     /locus_tag="IRB70_001429"
     CDS             29367..29921
                     /locus_tag="IRB70_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBC0631356.1"
                     /translation="MNKKLMYTFAIFIVAAITCISQPKKTTLRDKAMANYAFDYLSSP
                     GSLPFTTAATELSAIHGHSTSQYRLGEFYLHGSDGKPLDYTQARYWYEQSAEQENPRA
                     QSKLGWIYLKGLGVKPDTRKAILWYKEAAEQGYAHAQYTLGLIYRNGSGINVNHYESQ
                     KWLKLAAKQHYKNAERLLAGLPAH"
     gene            complement(29931..31358)
                     /locus_tag="IRB70_001430"
     CDS             complement(29931..31358)
                     /locus_tag="IRB70_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="J domain-containing protein"
                     /protein_id="HBC0631357.1"
                     /translation="MKNCWKILEIEETTDVDIIRRAYLALLPSFHPETDPQGFKQLRQ
                     AYEDALRIAQSPAKSVWQPEEHEVAEHEILLAFRALLASDSERFLPSAWQRFIQQLNY
                     CSMEDIDELRWSLCTIAMNTAHLSFECVVLLAERLRWLQEENVGEIDEEELESFLYAI
                     AKGNVFNFQTILHLPVAVQNDTIDFYQMFARIWSSHPEWLTLYLAQHRAVIIPDDANL
                     HRNLLRWYSTSRLDIPELLDYARSWREAEPDNEDARYYEYAQRVYCGEGESLLAELCD
                     YWREYPSTQADALMLQWCRQHRVDYYPLVVMMIEARDLVNDQGKPLLYVPGDSARTRF
                     HLYEILSDEKLSALGRSLVEMVLHKGRKPRISLTRDTEHTLWSLYLVAKQLVQASQPT
                     EESLMPIVSRLDAEDRCPLEALIIRRLLIQAANFTEKQTVEPEPQPQSMPVDDGGPGC
                     LGVIKIIFYIFIFAGLIGKILHLFG"
     gene            complement(31355..32062)
                     /locus_tag="IRB70_001431"
     CDS             complement(31355..32062)
                     /locus_tag="IRB70_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1266 domain-containing protein"
                     /protein_id="HBC0631358.1"
                     /translation="MDMESQKILFALSTPMEIRNECCLPSHSSPKMYLGTRFFDLSSS
                     WGIDDRDDLLRTIHRMIDNGHAARLAGLYHRWFRYSPCEWRDYLAELNEQGQAYAQFV
                     ASTAECCGEGGIKAWDYVRMGFLSRMGVLNNWLSEEESLWIQSRIHLRALRYYSNWQQ
                     YFAGYTFGRQYWQSPEDDDLPLLREFLARKEYDDSGNDMFYQLFASDDAYYATLPWQP
                     LADYPTCPETLKDMSDL"
     gene            32226..33203
                     /locus_tag="IRB70_001432"
     CDS             32226..33203
                     /locus_tag="IRB70_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415177.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SEL1-like repeat protein"
                     /protein_id="HBC0631359.1"
                     /translation="MIFTSSCCDNLSIDEIIERAEKGDCEAQYIIGFYYNRDSAIDSP
                     DDEKAFYWLKLAAEQGHCEAQYSLGQKYTEDKSRHKDNGQAIFWLKKAALQGHTFASN
                     ALGWIQDRGEDPNYKEAVAWYQIAAESGMSYAQNNLGWMYRNGNGVAQDYALAFFWYK
                     QAALQGHSYAQDNLADLYKDGEGVAQNKTLAAFWYLKSAQQGNRHAQFQIAWDYNAGE
                     GVDQDYKQAMYWYLKAAAQESVGAYVNIGYMYKHGQGVEKDYQAAFEWFTKAAECDNA
                     TAWYNLAIMYHYGEGRPVDLRQALDLYRKAQSSGTRDVSQKIREIEDLL"
     gene            complement(33273..33755)
                     /locus_tag="IRB70_001433"
     CDS             complement(33273..33755)
                     /locus_tag="IRB70_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon-containing protein"
                     /protein_id="HBC0631360.1"
                     /translation="MNKVAQYYRELVASLSERLRNGERDIDALVEQARERVIKTGELT
                     RTEVDELTRAVRRDLEEFAMSYEESLKEESDSVFMRVIKESLWQELADITDKTQLEWR
                     EVFQDLNHHGVYHSGEVVGLGNLVCEKCHFHLPIYTPEVLTLCPKCGHDQFQRRPFEP
                     "
     gene            33990..36572
                     /gene="leuS"
                     /locus_tag="IRB70_001434"
     CDS             33990..36572
                     /gene="leuS"
                     /locus_tag="IRB70_001434"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008456064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBC0631361.1"
                     /translation="MQEQYRPEEIESKVQLHWDEKRTFEVTEDESKEKYYCLSMLPYP
                     SGRLHMGHVRNYTIGDVIARYQRMLGKNVLQPIGWDAFGLPAEGAAVKNNTAPAPWTY
                     DNIAYMKNQLKMLGFGYDWSRELATCTPEYYRWEQKFFTELYKKGLVYKKTSAVNWCP
                     NDQTVLANEQVIDGCCWRCDTKVERKEIPQWFIKITAYADELLNDLDKLDHWPDTVKT
                     MQRNWIGRSEGVEITFNVNDYDNTLTVYTTRPDTFMGCTYLAVAAGHPLAQKAAENNP
                     ELAAFIDECRNTKVAEAEMATMEKKGVDTGFKAVHPLTGEEIPVWAANFVLMEYGTGA
                     VMAVPGHDQRDYEFASKYGLNIKPVILAADGSEPDLSQQALTEKGVLFNSGEFNGLDH
                     EAAFNAIADKLTAMGVGERKVNYRLRDWGVSRQRYWGAPIPMVTLEDGTVMPTPDDQL
                     PVILPEDVVMDGITSPIKADPEWAKTTVNGMPALRETDTFDTFMESSWYYARYTCPEY
                     KEGMLDSKAANYWLPVDIYIGGIEHAIMHLLYFRFFHKLMRDAGMVNSDEPAKQLLCQ
                     GMVLADAFYYVGENGERNWVSPVDAIVERDEKGRIVKAKDAAGHELVYTGMSKMSKSK
                     NNGIDPQVMVERYGADTVRLFMMFASPADMTLEWQESGVEGANRFLKRVWKLVYEHTA
                     KGDVAALNVDALTEDQKALRRDVHKTIAKVTDDIGRRQTFNTAIAAIMELMNKLAKAP
                     TDGEQDRALMQEALLAVVRMLNPFTPHICFTLWQELKGEGDIDNAPWPVADEKAMVED
                     STLVVVQVNGKVRAKITVPVDATEEQVRERAGQEHLVAKYLDGVTVRKVIYVPGKLLN
                     LVVG"
     gene            36587..37168
                     /gene="lptE"
                     /locus_tag="IRB70_001435"
     CDS             36587..37168
                     /gene="lptE"
                     /locus_tag="IRB70_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly lipoprotein LptE"
                     /protein_id="HBC0631362.1"
                     /translation="MRYLATLLLSLAVLITAGCGWHLRDTTQVPSTMKVMILDSGDPN
                     GPLSRAVRNQLRLNGVELLDKETTRKDVPSLRLGKVSIAKDTASVFRNGQTAEYQMIM
                     TVNATVLIPGRDIYPISAKVFRSFFDNPQMALAKDNEQDMIVKEMYDRAAEQLIRKLP
                     SIRAADIRSDEEQTSTTTDTPATPARVSTTLGN"
     gene            37168..38199
                     /gene="holA"
                     /locus_tag="IRB70_001436"
     CDS             37168..38199
                     /gene="holA"
                     /locus_tag="IRB70_001436"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBC0631363.1"
                     /translation="MIRLYPEQLRAQLNEGLRAAYLLLGNDPLLLQESQDAIRQVAAV
                     QGFEEHHTFSIDPNTDWNAIFSLCQAMSLFASRQTLLLLLPENGPNAAINEQLLTLTG
                     LLHDDLLLIVRGNKLSKAQENAAWFTALANRSVQVTCQTPEQAQLPRWVAARAKQLNL
                     ELDDAANQVLCYCYEGNLLALAQALERLSLLWPDGKLTLPRVEQAVNDAAHFTPFHWV
                     DALLMGKSKRALHILQQLRLEGSEPVILLRTLQRELLLLVNLKRQSAHTPLRALFDKH
                     RVWQNRRGMMGEALNRLSQPQLRQAVQLLTRTELTLKQDYGQSVWAELEGLSLLLCHK
                     PLADVFIDG"
     gene            38201..38842
                     /gene="nadD"
                     /locus_tag="IRB70_001437"
     CDS             38201..38842
                     /gene="nadD"
                     /locus_tag="IRB70_001437"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBC0631364.1"
                     /translation="MKSLQALFGGTFDPVHYGHLKPVETLANLIGLTRVTIIPNNVPP
                     HRPQPEANSVQRKHMLELAIADKPLFTLDERELKRNAPSYTAQTLKEWRQEQGPDVPL
                     AFIIGQDSLLTFPTWYEYETILDNAHLIVCRRPGYPLEMAQPQYQQWLEDHLTHNPED
                     LHLQPAGKIYLAETPWFNISATIIRERLQNGESCEDLLPEPVLTYINQQGLYR"
     gene            38866..39477
                     /locus_tag="IRB70_001438"
     CDS             38866..39477
                     /locus_tag="IRB70_001438"
                     /EC_number="3.1.3.73"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobalamin/alpha-ribazole phosphatase"
                     /protein_id="HBC0631365.1"
                     /translation="MRLWLIRHGETQANVDGLYSGHAPTPLTARGIEQAQNLHTLLHG
                     VSFDLVLCSELERAQHTARRVLSDRQLPVQIIPELNEMFFGDWEMRHHRDLMQEDAEN
                     YSAWCNDWQHAIPTNGEGFQAFSQRVERFIARLSEFQHYQNILVVSHQGVLSLLIARL
                     IGMPAEAMWHFRVDQGCWSAIDINQKFATLRVLNSRAIGVENA"
     gene            39737..40054
                     /gene="rsfS"
                     /locus_tag="IRB70_001439"
                     /gene_synonym="rsfA"
     CDS             39737..40054
                     /gene="rsfS"
                     /locus_tag="IRB70_001439"
                     /gene_synonym="rsfA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007373852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBC0631366.1"
                     /translation="MQGKALQDFVIDKIDDLKGQDIIALDVQGKSSITDCMIICTGTS
                     SRHVMSIADHVVQESRAAGLLPLGVEGENSADWIVVDLGDVIVHVMQEESRRLYELEK
                     LWS"
     gene            40058..40525
                     /gene="rlmH"
                     /locus_tag="IRB70_001440"
     CDS             40058..40525
                     /gene="rlmH"
                     /locus_tag="IRB70_001440"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBC0631367.1"
                     /translation="MKLQLVAVGTKMPDWVQTGFTEYLRRFPKDMPFELIEIPAGKRG
                     KNADIKRILDKEGEQMLAAAGKNRIVTLDIPGKPWDTPQLAAELERWKLDGRDVSLLI
                     GGPEGLSPACKAAAEQSWSLSALTLPHPLVRVLVAESLYRAWSITTNHPYHRE"
     gene            40556..42457
                     /gene="mrdA"
                     /locus_tag="IRB70_001441"
     CDS             40556..42457
                     /gene="mrdA"
                     /locus_tag="IRB70_001441"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-transpeptidase MrdA"
                     /protein_id="HBC0631368.1"
                     /translation="MKLQNSFRDYTAESALFVRRALVAFLGILLLTGVLIANLYNLQI
                     VRFTDYQTRSNENRIKLVPIAPSRGIIYDRNGIPLALNRTIYQIEMMPEKVDNVQQTL
                     DALRSVVDLTDDDIAAFRKERARSHRFTSIPVKTNLTEVQVARFAVNQYRFPGVEVKG
                     YKRRYYPYGSALTHVIGYVSKINDKDVERLNNDGKLANYAATHDIGKLGIERYYEDVL
                     HGQTGYEEVEVNNRGRVIRQLKEVPPQAGHDIYLTLDLKLQQYIETLLAGSRAAVVVT
                     DPRTGGVLALVSTPSYDPNLFVDGISSKDYSALLNDPNTPLVNRATQGVYPPASTVKP
                     YVAVSALSAGVITRNTTLFDPGWWQLPGSEKRYRDWKKWGHGRLNVTRSLEESADTFF
                     YQVAYDMGIDRLSEWMGKFGYGHYTGIDLAEERSGNMPTREWKQKRFKKPWYQGDTIP
                     VGIGQGYWTATPIQMSKALMILINDGIVKVPHLLMSTAEDGKQVPWVQPHEPPVGDIH
                     SGYWELAKDGMYGIANRPNGTAHKYFASAPYKIAAKSGTAQVFGLKANETYNAHKIAE
                     RLRDHKLMTAFAPYNNPQVAVAMILENGGAGPAVGTLMRQILDHIMLGDNNTDLPAEN
                     PAVAAAEDH"
     gene            42460..43572
                     /gene="mrdB"
                     /locus_tag="IRB70_001442"
                     /gene_synonym="rodA"
     CDS             42460..43572
                     /gene="mrdB"
                     /locus_tag="IRB70_001442"
                     /gene_synonym="rodA"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004885876.1"
                     /note="rod shape-determining protein RodA; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan glycosyltransferase MrdB"
                     /protein_id="HBC0631369.1"
                     /translation="MTDNPNKKTFWDKVHLDPTMLLILLALLVYSALVIWSASGQDIG
                     MMERKIGQIAMGLVIMVVMAQIPPRVYEGWAPYLYIICIILLVAVDAFGAISKGAQRW
                     LDLGIVRFQPSEIAKIAVPLMVARFINRDVCPPSLKNTAIALVLIFMPTLLVAAQPDL
                     GTSILVALSGLFVLFLSGLSWRLIGVAVVLVAAFIPILWFFLMHDYQRQRVMMLLDPE
                     SDPLGAGYHIIQSKIAIGSGGLRGKGWLHGTQSQLEFLPERHTDFIFAVLAEELGLVG
                     ILILLALYILLIMRGLWIAARAQTTFGRVMAGGLMLILFVYVFVNIGMVSGILPVVGV
                     PLPLVSYGGSALIVLMAGFGIVMSIHTHRKMLSKSV"
     gene            43583..44671
                     /gene="rlpA"
                     /locus_tag="IRB70_001443"
     CDS             43583..44671
                     /gene="rlpA"
                     /locus_tag="IRB70_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic peptidoglycan transglycosylase RlpA"
                     /protein_id="HBC0631370.1"
                     /translation="MRKQWLGICIAAGMLAACTSDDGQQQTVSVPQPAVCNGPIVEIS
                     GADPRFEPLNATANQDYQRDGKSYKIVQDPSRFSQAGLAAIYDAEPGSNLTASGEAFD
                     PTQLTAAHPTLPIPSYARITNLANGRMIVVRINDRGPYGNDRVISLSRAAADRLNTSN
                     NTKVRIDPIIVAQDGSLSGPGMACTTVAKQTYALPAPPDLSGGAGTSSVSGPQGDILP
                     VSNSTLKSEDPTGAPVTSSGFLGAPTTLAPGVLEGSEPTPAPQPVVTAPSTTPATSPA
                     MVTPQAASQSASGNFMVQVGAVSDQARAQQYQQQLGQKFGVPGRVTQNGAVWRIQLGP
                     FASKAEASTLQQRLQTEAQLQSFITTAQ"
     gene            44811..46022
                     /gene="dacA"
                     /locus_tag="IRB70_001444"
     CDS             44811..46022
                     /gene="dacA"
                     /locus_tag="IRB70_001444"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase DacA"
                     /protein_id="HBC0631371.1"
                     /translation="MNTIFSARIMKRLALTTALCTAFISAAHADDLNIKTMIPGVPQI
                     DAESYILIDYNSGKVLAEQNADVRRDPASLTKMMTSYVIGQAMKAGKFKETDLVTIGN
                     DAWATGNPVFKGSSLMFLKPGMQVPVSQLIRGINLQSGNDACVAMADFAAGSQDAFVG
                     LMNSYVNALGLKNTHFQTVHGLDADGQYSSARDMALIGQALIRDVPNEYSIYKEKEFT
                     FNGIRQLNRNGLLWDNSLNVDGIKTGHTDKAGYNLVASATEGQMRLISAVMGGRTFKG
                     REAESKKLLTWGFRFFETVNPLKVGKEFASEPVWFGDSDRASLGVDKDVYLTIPRGRM
                     KDLKASYVLNSSELHAPLQKNQVVGTINFQLDGKTIEQRPLVVLQEIPEGNFFGKIID
                     YIKLMFHHWFG"
     gene            46132..46395
                     /locus_tag="IRB70_001445"
     CDS             46132..46395
                     /locus_tag="IRB70_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbeD family protein"
                     /protein_id="HBC0631372.1"
                     /translation="MKTKLNELLEFPTPFTYKVMGQALPELVDQVVEVVQRHAPGDYT
                     PTVKPSSKGNYHSVSITINATHIEQVETLYEELGKIDIVRMVL"
     gene            46496..47137
                     /gene="lipB"
                     /locus_tag="IRB70_001446"
     CDS             46496..47137
                     /gene="lipB"
                     /locus_tag="IRB70_001446"
                     /EC_number="2.3.1.181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415163.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl(octanoyl) transferase LipB"
                     /protein_id="HBC0631373.1"
                     /translation="MYQDKILVRQLGLQPYEPISQAMHEFTDTRDESTLDEIWLVEHY
                     PVFTQGQAGKAEHILMPGDIPVIKSDRGGQVTYHGPGQQVMYVLLNLKRRKLGVRELV
                     TLLEQTVVNTLAELGIEAHPRADAPGVYVGEKKICSLGLRIRRGCSFHGLALNVNMDL
                     SPFLRINPCGYAGMEMAKISQWKPEATTNNIAPRLLENILALLNNPDFEYITA"
     gene            47397..48350
                     /locus_tag="IRB70_001447"
     CDS             47397..48350
                     /locus_tag="IRB70_001447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308694.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HBC0631374.1"
                     /translation="MDSNNQIETCLSRKSSEGKPQIFTTLRNIDLNLLTIFEAVYVHK
                     GIVNAAKVLNLTPSAISQSIQKLRVIFPDPLFIRKGQGVTPTAFAMHLHEYISQGLES
                     ILGALDIEGSYDKQRTITIATTPSVGALVLPVIYRAIKSHYPQLLLRNPPISDAENQL
                     SQFQTDLIIDNMFCTNRTVQHHVLFTDNMVLICREGNPLLSLEDDRETIDNAAHILLL
                     PEGQNFSGLRQRVQEMFPDRQISFTSYNILTIAALVANSDMLAIIPSRFYNLFSRCWP
                     LEKLPFPSLNEEQIDFSIHYNKFSLRDPILHGVIDVIRNAF"
     gene            48559..49524
                     /gene="lipA"
                     /locus_tag="IRB70_001448"
     CDS             48559..49524
                     /gene="lipA"
                     /locus_tag="IRB70_001448"
                     /EC_number="2.8.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoyl synthase"
                     /protein_id="HBC0631375.1"
                     /translation="MSKPIVMERGVKYRDADKMALIPVKNVATEREALLRKPEWMKIK
                     LPADSTRIQGIKAAMRKNGLHSVCEEASCPNLAECFNHGTATFMILGAICTRRCPFCD
                     VAHGRPVAPDANEPVKLAQTIADMALRYVVITSVDRDDLRDGGAQHFADCITAIREKS
                     PQIKIETLVPDFRGRMDRALDILTATPPDVFNHNLENVPRIYRQVRPGADYNWSLKLL
                     ERFKEAHPEIPTKSGLMVGLGETNEEIIEVMRDLRRHGVTMLTLGQYLQPSRHHLPVQ
                     RYVSPDEFDEMKAEALAMGFTHAACGPFVRSSYHADLQAKGMEVK"
     gene            complement(49625..49828)
                     /gene="tatE"
                     /locus_tag="IRB70_001449"
     CDS             complement(49625..49828)
                     /gene="tatE"
                     /locus_tag="IRB70_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="twin-arginine translocase subunit TatE"
                     /protein_id="HBC0631376.1"
                     /translation="MGEISITKLLVVAALVVLLFGTKKLRTLGGDLGAAIKGFKKAMN
                     DDDAAAKKGADVDLQAEKLSHKE"
     gene            complement(49957..50745)
                     /locus_tag="IRB70_001450"
     CDS             complement(49957..50745)
                     /locus_tag="IRB70_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deaminated glutathione amidase"
                     /protein_id="HBC0631377.1"
                     /translation="MLVAAGQFAVTSVWEKNAEICASLMAQAAENDVSLFVLPEALLA
                     RDDHDADLSVKSAQLLEGEFLGRLRRESKRNMMTTILTIHVPSTPGRAWNMLVALQAG
                     NIVARYAKLHLYDAFAIQESRHVDAGNEIAPLLEVEGMKVGLMTCYDLRFPELALAQA
                     LQGAEILVLPAAWVRGPLKEHHWSTLLAARALDTTCYMVAAGECGNKNIGQSRIIDPF
                     GVTIAAASEMPSLIMAEVTPERVRQVRAQLPVLNNRRFAPPQLL"
     gene            50841..51224
                     /gene="crcB"
                     /locus_tag="IRB70_001451"
     CDS             50841..51224
                     /gene="crcB"
                     /locus_tag="IRB70_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HBC0631378.1"
                     /translation="MLQLLLAVFIGGGTGSVARWLLSMRFNPLHQAIPLGTLAANLIG
                     AFIIGMGFAWFSRMTNIDPVWKVLITTGFCGGLTTFSTFSAEVVFLLQEGRFGWALLN
                     VFVNLLGSFAMTALAFWLFSASTAH"
     gene            complement(51278..51487)
                     /gene="cspE"
                     /locus_tag="IRB70_001452"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             complement(51278..51487)
                     /gene="cspE"
                     /locus_tag="IRB70_001452"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HBC0631379.1"
                     /translation="MSKIKGNVKWFNESKGFGFITPEDGSKDVFVHFSAIQTNGFKTL
                     AEGQRVEFEITNGAKGPSAANVIAL"
     gene            complement(51662..52222)
                     /gene="pagP"
                     /locus_tag="IRB70_001453"
     CDS             complement(51662..52222)
                     /gene="pagP"
                     /locus_tag="IRB70_001453"
                     /EC_number="2.3.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) palmitoyltransferase PagP"
                     /protein_id="HBC0631380.1"
                     /translation="MNVSKYVAIFFFVFIQLISVGKVFANADEWMTTFRENIAQTWQQ
                     PEHYDLYIPAITWHARFAYDKEKTDRYNERPWGGGFGQSRWDEKGNWHGLYAMAFKDS
                     WNKWEPIAGYGWESTWRPLADENFHLGLGFTAGVTARDNWNYIPLPVLLPLASVGYGP
                     ATFQMTYIPGTYNNGNVYFAWMRFQF"
     gene            52811..54196
                     /gene="dcuC"
                     /locus_tag="IRB70_001454"
     CDS             52811..54196
                     /gene="dcuC"
                     /locus_tag="IRB70_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HBC0631381.1"
                     /translation="MLTFIELLIGVMVIVGVARYIIKGYSATGVLFVGGLLLLIISAI
                     MGHKVLPSSQASTGYSATDIVEYVKILLMSRGGDLGMMIMMLCGFAAYMTHIGANDMV
                     VKLASKPLQYINSPYLLMIAAYFVACLMSLAVSSATGLGVLLMATLFPVMVNVGISRG
                     AAAAICASPAAIILAPTSGDVVLAAQASEMSLIDFAFKTTLPISIAAIIGMAIAHFFW
                     QRYLDKKEHISHEMLDVSEITTTAPAFYAILPFTPIIGVLIFDGKWGPQLHIITILVI
                     CMLIASILEFIRSFNTQKVFSGLEVAYRGMADAFANVVMLLVAAGVFAQGLSTIGFIQ
                     SLISIATSFGSASIILMLVLVILTMLAAVTTGSGNAPFYAFVEMIPKLAHSSGINPAY
                     LTIPMLQASNLGRTLSPVSGVVVAVAGMAKISPFEVVKRTSVPVLVGLVIVIVATELM
                     VPGTAAAVTGK"
     gene            complement(54237..54917)
                     /gene="dpiA"
                     /locus_tag="IRB70_001455"
                     /gene_synonym="citB"
     CDS             complement(54237..54917)
                     /gene="dpiA"
                     /locus_tag="IRB70_001455"
                     /gene_synonym="citB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component response regulator DpiA"
                     /protein_id="HBC0631382.1"
                     /translation="MTAPLTLLIVEDETPLAEMHAEYIRHIPGFSQILLAGNLAQARM
                     MIERFKPGLILLDNYLPDGRGINLLHELVQAHYPGDVVFTTAASDMETVSEAVRCGVF
                     DYLIKPIAYERLGQTLTRFRQRKHMLESIDSASQKQIDEMFNAYARGEPKDELPTGID
                     PLTLNAVRKLFKEPGVQHTAETVAQALTISRTTARRYLEYCASRHLIIAEIVHGKVGR
                     PQRIYHSG"
     gene            complement(54886..56544)
                     /gene="dpiB"
                     /locus_tag="IRB70_001456"
     CDS             complement(54886..56544)
                     /gene="dpiB"
                     /locus_tag="IRB70_001456"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase DpiB"
                     /protein_id="HBC0631383.1"
                     /translation="MLQLNENKQFAFFQRLAFPLRIFLLILVFSIFVIAALAQYFTAS
                     FEDYLTLHVRDMAMNQAKIIASNDSIISAVKTRDYKRLATIADKLQRDTDFDYVVIGD
                     RHSIRLYHPNPEKIGYPMQFTKPGALEKGESYFITGKGSIGMAMRAKTPIFDDDGKVI
                     GVVSIGYLVSKIDSWRAEFLLPMAGVFVVLLGILMLLSWFLAAHIRRQMMGMEPKQIA
                     RVVRQQEALFSSVYEGLIAVDPHGYITAINRNARKMLGLSSPGRQWLGKPIAEVVRPA
                     DFFTEQIDEKRQDVVANFNGLSVIANREAIRSGDDLLGAIISFRSKDEISTLNAQLTQ
                     IKQYVESLRTLRHEHLNWMSTLNGLLQMKEYDRVLAMVQGESQAQQQLIDSLREAFAD
                     RQVAGLLFGKVQRARELGLKMVIVPGSQLSQLPPGLDSTEFAAIVGNLLDNAFEASLR
                     SDEGNKIVELFLSDEGDDVVIEVADQGCGVPESLRDKIFEQGVSTRADEPGEHGIGLY
                     LIASYVTRCGGVITLEDNDPCGTLFSIYIPKVKPNDSSINPIDR"
BASE COUNT        14203 a        14488 c        14007 g        13875 t
ORIGIN      
        1 cggagcgcgg cgtttgggtt tgtttgctat tttttgccgg atgcggcgtg aacgctctat
       61 ccgacaacgt aaacttactc gcctactttc gcccaggtat cacgcaaccc aacggtgcgg
      121 ttaaataccg gtttttccgc cgtagaatgg cggctgtcga gacagaagta accttcacgc
      181 tcaaactgga atgctttacc cgctaccgca tctttcagcg acggttcagc aaagccctgt
      241 ttgatcacca gcgattccgg gttaatcacc gacaggaaat catccgcagc accagggttc
      301 ggcacgctga acagacggtc atacaaacgg atttcaaccg gcagcgcatg tgccgcgctc
      361 acccagtgaa taacgccttt gactttacga ccatctgccg gatctttgct taaggtgtcg
      421 gcgtcataag tacagaagat ggtggtgata ttgccttcgg catctttctc cacgcgttct
      481 gccttaatga cgtaagcatt acgcagacgc acttctttac ccagcaccag acgtttgtac
      541 tgcttgttag cttcttcgcg gaaatcggcg cgatcgatcc aaatctcacc gctaaacggc
      601 acctgacggc tccccatttc cggtttgttc ggatggttcg gcatggtaac catttcgcct
      661 tcgccctgat agttttcgat aaccagtttc accggatcga taaccgccat tgcgcgcggg
      721 gcgttttcgt tgagatcttc acggatgcag gattccagcg acgccatctc aatggtgttg
      781 tcctgcttgg tcacgccgat gcgtttgcag aactcacgaa tagaagccgc agtgtaacca
      841 cgacgacgca gaccggaaat ggtcggcata cgcgggtcat cccagccttc aacgtgcttg
      901 tcggtcacca gcaggttcag cttacgcttg gacatcacag tgtattccag attcaggcgc
      961 gagaattcgt actggcgcgg gtgaacagga atggtgatgt tgtccagcac ccagtcgtac
     1021 aggcgacggt tgtcctggaa ctcaagcgta cacagagagt gcgtaatacc ttccagcgca
     1081 tcgctgatgc agtgggtaaa gtcgtacatc gggtagatgc accacttgtt gccagtctgg
     1141 tggtgttcag caaacttaat gcggtacagc accggatcgc gcatcacgat aaacggcgaa
     1201 gccatgtcga tcttcgcacg caggcaggct ttaccttctt caaaaccgcc ggtacgcatt
     1261 ttctcgaaca gcgccaggtt ctcttcaacg ctgcggtcgc ggtacgggct gtttttaccc
     1321 ggctgcgtca gggtgccgcg gtattcgcgg atctgttccg gtgtcagttc atcaacgtac
     1381 gccaggcctt tattgatcag ttcgatcgca taggcgtgga gctgatcaaa ataatcggag
     1441 gagtaacgga cgttaccaga ccagtgaaaa cctaaccact caacgtcgtt tttgatcgac
     1501 tcaacatact cgatatcttc ttttaccggg ttagtgtcgt cgaaacgcag gttgcactgg
     1561 cctttatagt cctgggcgat cccgaagttc aggcagatag atttcgcatg gccaatatgc
     1621 agatagccat tcggctccgg cgggaaacgg gtgtgtactg tggtgtgctt accactggcc
     1681 agatcttcat cgatgatctg acgaataaag ttagtcgggc gggcttctgc ctcactcatc
     1741 gtggattcct caaagcgtaa acaacgtata acggcgtatg atcttataag cgggacaggc
     1801 tgacaactgt tagttagtga aaatcgaaaa tctcactgag attatgggga tgattgatga
     1861 aaaaaaaagc gacagagaag atctccaccg cttgtcattg ttggatgcga cgctcaagcg
     1921 tcgcatcagg cataaagcag attacttttt gatttcatac agcggcgttt gacccgccac
     1981 gacatggccc tgagctttaa tgatcaagcc gctgaaatcg tcgatattgc tgcaaaccac
     2041 cgggctaatc atcgagcggg cgttttcgtt cagataatcc agatccattt ccagaatcgg
     2101 ttgccctgcg cttacttgcg cgccctcttc caccagacgt ttaaagcctt taccttccag
     2161 cgctacggtg tcgataccca tatggacgac aatctccgcg cctttttcag tttccaggca
     2221 gaatgcgtgg ttggtgttga agattttcac gatagtccct gcggctggtg atacgacgat
     2281 tttatctgtc ggtttcaccg ccacaccgtc acccaccgct ttgctggcga atgcttcgtc
     2341 aggaacctga tccagtgcca caacatcacc ggtaatcggc gataccagct ccgcgacaga
     2401 caccgcgttt ggtacagcct gcggttttgc tacaggcgcg gcagttgcag gcgcagtttc
     2461 agctgacgca gcggctaccg gaccacgggc aacgactttc ttcatcgcat cgccgatgga
     2521 ttctgctttc gcgccaacaa tcacctgaat agtctgtttg ttcagtttca ctaccccaga
     2581 agcacccaga cgtttacaca tcgtatcgtt aacgcgggca gagtcagcca ctgtaaggcg
     2641 cagacgggtg atacaggcgt caattgcttt caggttgtca gtgccgccaa ccgcagcaat
     2701 atagttggtt gccagttgat tgagaccttc ttcagtattg ctgttagcct cttcagtaac
     2761 gatctcgtct tctttatctt cacgacccgg cgttttcagg ttgaacatgc ggataaccaa
     2821 actgaacacc acgaagtaga tagcgaagaa gacaaccccc atcaccagca gcatccagac
     2881 gttctggctg gcggccggca ggttatacat caacgcgtag tcgatagccc ccgcagagaa
     2941 agagaagccg gcatggatac ccagcaacgt tgccacaaac aggctgatac cggtcagcag
     3001 tgcgtgcagg aggtacagca gcggtgcaag gaacatgaac aggaattcca gcggctcagt
     3061 cacaccggtc aggaacgcag taacagcaac agaaagcaac atcccgccaa ccatcggacg
     3121 gcgctctttc ggtgctgcga agtacatcgc cagcgccgca cccggcagac cgaacatcat
     3181 gatcgggaag aagccggaca tgaacatccc cgcggtgccg tcaccggcat agaagcggtt
     3241 gatatcaccg tggaaaaccg tacccgccgc gttggtgaat tcaccaatct ggaaccaggc
     3301 gatggtgttc agcacctgat gcagaccggt tgggatcagc agacggttga tgaaaccaaa
     3361 gataccggaa cccagcgcgc ccgcagaaac gatccactcg ccgcctgcat ggatagcgtg
     3421 ctgtaccggc ggccagacgt aaccaaaaat ggccgccagc accaggcaga agaagccggt
     3481 ggcaatcggc acaaagcgtt tgccgccgaa gaaactcagg aagtccggca gtttaatatc
     3541 ggaccaacgg ttataagctg cgccaccaac cagaccggta atgatacccg ccagtacacc
     3601 catgttaatt tctgggttga tggtaaccat cgctttggtt aacacaaagt aacctaccgc
     3661 acccgccagt gccgccgcac ctgcgctgtc tttcgaccag ctggatgcca caccgatggc
     3721 gaagattaat gcgaggttat caaaaatcgc accgcccgcc tgggcaataa acgcaacgtt
     3781 aagtaaatct ggctgaccga atcgcagcaa cagcgccgcc accggcagca ccgcgatagg
     3841 gagctgtaac gccctaccga gtcgctggaa aaaacctaaa atattcatct tattccccct
     3901 acgagaaccc tatttggctc atttaaagcc gtatttttat tttgctgcaa attgtactgc
     3961 cgatgttctg taatcagatt gttagatcat ctgctacaga gtgtgtgaaa atttaattcg
     4021 tatcgcaaat taaacgcgtg tcttttgtga gttttgtcac caaatatcgt tatcatcact
     4081 cccttttact ggctaaacca gaaaacttat tttatcattc aaaaaatcag gtcggattga
     4141 cgcctgtctg cgcaaatcca ggttacgctt aaagatgcct aatccgccaa cggcttacat
     4201 tttacttatt gaggtgaata atgagactga tccccctgac taccgctgaa caggtcggca
     4261 aatgggctgc tcgccatatc gtcaatcgta tcaatgcgtt caaaccgact gctgatcgtc
     4321 cgtttgttct gggcctgccg actggcggca cgccgatgac cacctataaa gcgttagtcg
     4381 aaatgcataa agcaggccag gtcagcttta agcacgttgt caccttcaac atggacgaat
     4441 atgtcggtct gccgaaagag catccggaaa gctactacag ctttatgcac cgtaatttct
     4501 tcgatcacgt tgatattcca gcagaaaaca tcaaccttct caacggcaac gccccggata
     4561 tcgacgccga gtgccgccag tatgaagaaa aaatccgttc ttacggaaaa attcatctgt
     4621 ttatgggcgg tgtaggtaac gacggtcata ttgcatttaa cgaaccggcg tcttctctgg
     4681 cttctcgtac tcgtatcaaa accctgactc atgacactcg cgtcgcgaac tctcgtttct
     4741 ttgataacga tgtcaatcag gtgccaaaat atgccctgac tgtcggtgtt ggtacattgt
     4801 tggatgccga agaagtgatg attctggtgc tgggtagcca gaaagcactg gcactgcagg
     4861 ccgccgttga aggttgcgtg aaccacatgt ggaccatcag ctgtctgcaa ctgcatccaa
     4921 aagcgatcat ggtgtgcgat gaaccttcca ccatggagct gaaagttaag actttaagat
     4981 atttcaatga attagaagca gaaaatatca aaggtctgta attgttatcc ctgccctggc
     5041 tccttgctca gggcaatatt ttttaaaatc gggggtcaga atgtatgcat taacccaggg
     5101 ccggatcttt accggccacg aatttcttga tgaccacgcg gttgttatcg ctgatggcct
     5161 gattaaaagc gtctgtccgg tagcggaact gccgccagag atcgaacaac gttcactgaa
     5221 cggggccatt ctctcccccg gttttatcga tgtgcagcta aacggctgcg gcggcgtaca
     5281 gtttaacgac accgctgaag cagtcagcgt ggaaacgctg gaaatcatgc agaaagccaa
     5341 tgagaaatca ggctgtacta actatctgcc gacgcttatc accaccagcg atgagctgat
     5401 gaaacagggc gtgcgcgtta tgcgcgagta cctggcaaaa catccgaacc aggcgttagg
     5461 tctgcatctg gaaggtccgt ggctgaatct ggtaaaaaaa ggcacccata atccgaattt
     5521 tgtgcgtaag cctgatgccg cgctggtcga tttcctgtgt gagaacgccg acgtgattac
     5581 caaagtgact ctggcaccgg aaatggttcc agcggaagtc atcagcaaac tggcaaatgc
     5641 cgggattgtg gtttctgctg gtcactccaa cgcgacgttg aaagaagcga aagccggttt
     5701 ccgcgcgggg attacctttg ccacccatct gtacaacgcg atgccgtata ttaccggtcg
     5761 tgaaccgggc ctggcgggcg cgatcctcga cgaagctgac atttattgcg gtattattgc
     5821 tgatggcctg catgttgatt acgccaacat tcgtaacgct aaacgtctga aaggcgacaa
     5881 attgtgtctg gttaccgatg ccaccgcgcc agcaggtgcc aacattgaac agttcatttt
     5941 tgcgggtaaa acaatatact accgtaatgg actttgtgtg gatgagaacg gtacgttaag
     6001 cggttcatcc ttaaccatga ttgaaggcgt gcgtaatctg gtcgaacatt gtggtatcgc
     6061 actggatgaa gtgctgcgta tggcgacgct ctatccggca cgtgcgattg gcgttgagaa
     6121 acgtctcggc acgctcgccg caggtaaagt agccaacctg actgcattca cacctgattt
     6181 taaaatcacc aggaccatcg ttaacggtaa cgaggtcgta actcaataag agaaagtatg
     6241 acaccaggcg gacaagctca gataggtaat gttgatctcg taaaacagct taacagcgcg
     6301 gcggtttatc gcctgattga ccagtacgga ccaatctcgc ggattcagat tgccgagcaa
     6361 agtcagcttg cccccgccag cgtaaccaaa attacgcgtc agcttatcga acgcgggctg
     6421 atcaaagaag ttgatcagca ggcctccacc gggggccgcc gcgctatctc tatcgtcacc
     6481 gaaacccgca atttccacgc aatcggcgta cggcttggtc gtcacgacgc caccatcact
     6541 ctgtttgatc ttagtagcaa agtgctggca gaagaacatt acccgctgcc ggaacgtacc
     6601 cagcagacgc tggaacatgc cctgcttaac gccattgctc agtttattga tagctaccag
     6661 cgcaaactgc gcgagctgat cgccatttcc gtgatcctgc caggacttgt tgacccggac
     6721 agcggcaaaa ttcattacat gccgcatatt caggtagaaa actgggggct ggtagaagca
     6781 ctggaagaac gttttaaagt gacctgtttt gtcggccacg atatccgcag tctggcgctg
     6841 gcagagcact acttcggtgc aagtcaggat tgcgaagact ccattctggt gcgtgtccat
     6901 cgtggaaccg gggccgggat tatctctaac gggcgaattt ttatcgggcg caacggcaac
     6961 gtcggtgaaa ttggccatat tcaggtcgaa ccgctgggtg aacgctgcca ctgcggcaac
     7021 tttggctgcc tggaaactat cgccgccaac gctgccattg aacaacgggt gttgaatctg
     7081 ttaaagcagg gctaccagag ccgcgtgccg ctggacgact gcaccatcaa aactatctgc
     7141 aaagccgcga acaagggcga tagcctggcg tcggaagtga ttgaatatgt cggtcgtcat
     7201 ctgggtaaaa ccatcgccat tgctatcaac ttatttaacc cgcaaaaaat tgttattgct
     7261 ggtgaaatca ccgaagccga taaagtgctg ctccctgcta ttgaaagctg cattaatacc
     7321 caggcgctga aggcgtttcg cactaatctg ccggtggtac gttctgagct ggatcaccgc
     7381 tcggcaatcg gcgcttttgc gctggtaaaa cgcgccatgc tcaacggtat tttgctccag
     7441 catttgctgg aaaattaatg tgcttttata gtggcgctta ttgttgtcaa tattctgggt
     7501 agtccatgac cattaaaaat gtaatttgcg atatcgacgg cgtgctgatg cacgataacg
     7561 tcgccgtacc gggtgcagcg gaatttttgc acgggattat ggataaaggc ctgccgctgg
     7621 tgttgctgac caactatcct tcgcagaccg ggcaagatct ggcgaaccgc tttgccactg
     7681 ccggtgtcga tgtacctgac agcgtgtttt atacctctgc aatggcgacc gccgatttcc
     7741 tgcgtcgcca ggaaggcaag aaagcgtatg tggtgggcga aggcgcactg attcatgaac
     7801 tgtacaaagc cggtttcact attaccgatg tgaaccctga tttcgtgatt gttggtgaaa
     7861 cgcgttccta caactgggac atgatgcata aagcagccta tttcgtcgct aacggtgcac
     7921 gctttatcgc caccaacccg gacacccacg ggcgcggttt ttatccggcc tgtggcgcgt
     7981 tgtgtgcagg gatcgaaaaa atctccgggc gtaaaccgtt ctatgttggt aaaccgagtc
     8041 cgtggatcat ccgcgcggca ttaaacaaaa tgcaggcgca ttcggaagaa acggtgattg
     8101 tcggcgataa cctgcgtacc gatattctgg cgggcttcca ggcgggtctg gagacgattc
     8161 tggtgctttc tggtgtttca tcgctcgacg atatcgacag tatgccgttc cgcccaagct
     8221 ggatttaccc gtcggtcgct gaaatcgacg ttatctgaat agcaaccacg cctcagggcg
     8281 tggtttctta tttttagcca tcattaaaat catcctattc aataaaaccc gtcaaaaatt
     8341 atcgatccat caataaatac gccaccacac cctatccttt ttcacaaatc agcaatcgcc
     8401 attacgtttt ttatttttcc accgccaaat cgcttgcgca ccgtgctgct ttgcggcatt
     8461 ttttaaacaa gcaaacacaa caagcaacaa ataccaggtt aacggagaag gttatgtgtt
     8521 caatttttgg cgtattcgat atcaaaacag acgcagttga gctgcgtaag aaagcactcg
     8581 agctgtcacg cctgatgcgt catcgtggcc cggactggtc cggtatttat gccagcgata
     8641 acgccattct cgcccacgaa cgtctgtcaa ttgttgacgt taacgcgggg gcgcaacctc
     8701 tctacaacca acaaaaaact catgtgctgg cagtaaacgg tgaaatctac aaccaccagg
     8761 cattgcgcgc tgaatatggc gatcgttacc aattccagac cgggtctgac tgtgaagtga
     8821 tcctcgcgct gtatcaggaa aaagggccgg aatttctcga cgacttgcag ggcatgtttg
     8881 cctttgccct gtacgacagc gaaaaagatg catatctgat tggtcgcgac catctgggga
     8941 tcatcccact gtatatgggc tatgacgaac acggtcagct gtatgtggcc tcagaaatga
     9001 aagccctcgt gccagtttgc cgcacgatta aagagtttcc ggcggggagc tatttgtgga
     9061 gtcaggacgg cgaaatccgt tcttattatc atcgcgactg gttcgactac gatgcggtga
     9121 aagataacgt gaccgacaaa aacgagctgc gtcaggcact ggaagattcc gttaaaagcc
     9181 atctgatgtc tgatgtgcct tacggtgtgc tgctatctgg tggcctggat tcctcaatca
     9241 tttccgctat caccaagaaa tacgccgccc gtcgcgtgga agatcaggaa cgctctgaag
     9301 cctggtggcc gcagctgcac tcctttgctg taggtctgcc gggttcaccg gatctgaagg
     9361 cagcccagga agtggcaaac catctgggca ctgtgcatca tgaaattcac ttcactgtac
     9421 aggaaggtct ggacgccatc cgcgacgtga tttaccacat cgaaacctat gatgtgacca
     9481 ctattcgcgc ttcaacaccg atgtatttaa tgtcgcgtaa gatcaaggcg atgggcatta
     9541 aaatggtgct gtccggtgaa ggatctgatg aagtgtttgg cggttatcta tacttccaca
     9601 aagcgccgaa tgccaaagaa ctgcatgaag agacggtgcg taaactgctg gccctgcata
     9661 tgtatgactg cgcgcgtgcc aacaaagcga tgtccgcctg gggcgtggaa gcacgcgttc
     9721 cgttcctcga caaaaaattc ctcgacgtgg cgatgcgcat taacccacag gataaaatgt
     9781 gcggtaacgg caaaatggaa aaacacatcc tgcgtgaatg ttttgaagcg tatctgcccg
     9841 caagcgtggc ctggcggcag aaagagcagt tctccgatgg cgtcggttac agttggatcg
     9901 acaccctgaa agaagtggcg gcgcagcagg tttctgatca acagctggaa actgcccgct
     9961 tccgcttccc gtacaacacg ccgacgtcca aagaagcgta tctgtaccgc gagatctttg
    10021 aagaactgtt cccgcttccg agcgccgctg agtgcgtgcc gggcggtcct tccgtcgcgt
    10081 gttcttccgc taaagcgatc gaatgggatg aagcgttcaa aaaaatggac gatccatctg
    10141 gtcgtgcggt tggtgttcac cagtcggcgt acaagtaaga aatgcgaaac agccccggta
    10201 aaatccgggg ctgtttcagt tattgaggtg cttgttgatt ctgatatgca gtaaggaaat
    10261 gttccgggtt tgccacatca ctgtttgaca attcatcact gtaggccacc gaccaggtcg
    10321 cctgctcatc cggaatatgc aggctgccat tcccctcttt caggcgtaat aactcaaaag
    10381 atttgccctt aattacggcg gtataggatt tttcaccttc ctgtaatgct ttcactttac
    10441 agcgaaaaat ctggccatcg atgtcattat caacatgcga tacctgaatg agggcttcat
    10501 tagaggcttt cggccctatc cgcatcatcc acaccacagc gccttcctgc ccacgatagc
    10561 caaaaacata tttaccgatt tccggtttga ccgtatcggc aaacgcagat tgcataagta
    10621 ataacgcacc catcagcgcc gtcataaaac gcagcatagt attccctcaa taaatcgcct
    10681 gaagtggtag cagagatgca ggcgtagcga tccctgccct gtcctgttgc aacgggccag
    10741 tatttcatag attaatttcc caccactatt gttgaattcc gaatttcatc ctgtatgaca
    10801 aaagaatggc tgtagggtgg ggaaaaaaca caaagtaaac aataattgac gaatatagcg
    10861 ccacgctgtt cgcaacctaa ccaaacagtc actttcgagc aattttcctt gaaaaagagg
    10921 ttgacgctgc aaggctctat acgcataatg cgccccgcaa cgccgataag gtatcgcgaa
    10981 aaaaaagatg gctacgtagc tcagttggtt agagcacatc actcataatg atggggtcac
    11041 aggttcgaat cccgtcgtag ccaccatctt ttttgcggga gtggcgaaat tggtagacgc
    11101 accagattta ggttctggcg ccgcaaggtg tgcgagttca agtctcgcct cccgcaccat
    11161 tcaccagaaa gcgttgtacg gatggggtat cgccaagcgg taaggcaccg gtttttgata
    11221 ccggcattcc ctggttcgaa tccaggtacc ccagccatcg aagaaacaat ctggctacgt
    11281 agctcagttg gttagagcac atcactcata atgatggggt cacaggttcg aatcccgtcg
    11341 tagccaccaa attctgaatg tgtcgaataa gttcggcaaa ttcaaaaacc aatttgttgg
    11401 ggtatcgcca agcggtaagg caccggattc tgattccggc attccgaggt tcgaatcctc
    11461 gtaccccagc cacattaaaa aagctcgctt cggcgagctt tttgcttttc tgcgtatatt
    11521 caatgtcgaa tgcgatgttg acacgtctta tccttcaaag tcggatgcga cgctgacgcg
    11581 tcttatccga cctacggttg gcatgcatcc ggcaatgttg taaggctaca accctaacgc
    11641 atatttcagc gcctgacgtt tcaacacgcc agcacgctcc gccgccatta atccgagatt
    11701 acgcataaaa cgcagtggtg gcagattatt gctgaatccg gcataaaaca aatccatacc
    11761 gctttgcata atgaagttat ccgccatacg ccgcatctgg taacgcttga ggacaggata
    11821 actggcccac gcttcaccgt agctgcgggc attcaccaga acgtcaatca gcgcatcaac
    11881 atcgcgataa ccgaggttaa ccccctgccc cgccaacgga tgaatggtgt gcgcggcatc
    11941 gcccaccagc gtaagccctg gttgcacata ctgcaacgca tggcgacgtg tcagcggaaa
    12001 cgcaccagcg gcaagcggtg tcacgtaacc cagacgcgac gggaaatgct tcgcgatttc
    12061 cgcctggagc tgcgccatat tcatattctg caactggcga atacgcgccg gagagtcata
    12121 ccacaccagc gacgcccagt tatcaaacag cggcaaaaac gcacgcggcc cgtccggagt
    12181 aaactgctgc caggtgctgt cgccgggatc attctcgcac tgtacgctaa tcaacataca
    12241 cgactgcgca tactgccagg catgaacgcc aattcccgcc atttgccgca cctgcgaatt
    12301 tgcaccgtca gcgccaatca ccagcttcgc ctggatcact tcaccgcctt tcagctccag
    12361 ctcctgaaga tcattatctc gatgtaatgc aatcagcgag cctggcacac gtaacgttac
    12421 tttcggatgc gcttccagcg cctgccacag cgcctgttgc aggacagtgt tttccaccat
    12481 gtagccaagc aacggtagct taagttcagc ggcgtcaaac accacatgcg ccgtttccca
    12541 ctcccacgtt tccagtctgc ggtaaggatg gcaacgcata gcctgtaccg cgtcccagat
    12601 gcctaaacct ttaagcaatg ataccgaagc cgcactaatc gccgagatcc gcacgtcagg
    12661 ctggctgtca gcgacaaacg gtgcaggttc tgcgtgctcg atcaccgtta ccgcaaatcc
    12721 gtgctgtgcc agccccagcg ccagtgcgcc gccgaccatt cctccgccga caatggcaat
    12781 ttccgttggt tgatttgtca tggtcaatca tcctgttagc aatatgcttt aagtttacag
    12841 gatttttacc cccaagggct gataacgctc atactggtca caacggcagc aaagcattac
    12901 actatgcgcc ctgcattcct ggctactatt tcgcaagagc aagtcgatga ccaaaaaact
    12961 ccatattaaa acctggggct gtcagatgaa cgagtacgat tcatcgaaga tggccgatct
    13021 gctggatgcc acccacggct atcaactgac cgacgtggcg gaagaagcgg atgtgctgct
    13081 gctgaacacc tgctcaatcc gcgagaaggc tcaggaaaaa gtcttccatc agttgggtcg
    13141 ctggaaactg ttaaaagaga agaatccaga cctgataatc ggcgtcggcg gctgcgtggc
    13201 atcgcaagaa ggcgagcaca ttcgccagcg cgcccactat gtcgatatta tttttgggcc
    13261 gcaaacgctg caccgtctgc cggagatgat caactccgtg cgcggcgacc gcagcccggt
    13321 tgtagatatc agcttcccgg aaatcgagaa gtttgaccgt ctgccagaac cgcgcgccga
    13381 agggccgacc gcgtttgtct ccatcatgga aggctgcaat aaatattgca cctactgcgt
    13441 ggtgccttac acccgtggtg aagaggtaag ccgtccgtcc gacgatattc tgtttgaaat
    13501 tgcccagctt gcggctcagg gcgtgcgtga agtcaacctg ctcggtcaga acgtgaacgc
    13561 ctggcgtggt gaaaactacg acggcaccac cggatcgttt gccgatctgc tgcgtctggt
    13621 tgcggcgatc gacgggatcg atcgtattcg ctttaccacc agccatccga tcgaattcac
    13681 cgacgatatc atcgaagtgt atcgcgacac gccggagctg gtgagcttcc tgcatctgcc
    13741 ggtacagagc ggttccgatc gcattctgaa cctgatggga cgtacccata cagcgctgga
    13801 gtacaaagcg atcatccgta aactgcgtgc ggcgcgtccg gatattcaga tcagttctga
    13861 cttcatcgtt ggcttccctg gcgaaaccac cgaagacttc gagaaaacga tgaagctgat
    13921 tgccgacgtc aatttcgaca tgagctacag ctttatcttc tctgcacgtc caggtacacc
    13981 agccgccgat atggttgatg atgttccgga agaagagaag aagcagcgtc tgtatattct
    14041 gcaagaacgt attaatcagc aagcaatggc atggagccgc cggatgctcg gcaccaccca
    14101 gcgtattctg gtagaaggta catcgcgtaa gagcatcatg gagctttccg gtcgcactga
    14161 aaataaccgc gtggtcaact ttgaaggcac gccagatatg atcggtaaat tcgtcgatgt
    14221 agaaattacc gacgtctacc cgaactctct gcgcggtaaa gtggtgcgta ctgaagatga
    14281 aatgggtctg cgcgtggcag aaacgccgga atcggtgatt gcccgtaccc gcaaagaaaa
    14341 cgaccttggc gtgggttatt atcagccgta attctcaggc ccgccgttcc ggtgggcctt
    14401 gttttttctc tctttatccc catctttatc gcaatgcttg cgcctttttc ctgtggcgtg
    14461 aataatttcc ttataggccg gtgaatgttc agcttccggc ggcatacaga taagaggaac
    14521 ggtttgaaca tagacactcg cgaaatcacc ctggagccag cagacaatgc gcgtctgttg
    14581 agcctgtgcg gcccgtttga tgacaacatc aagcagctcg aacgccgtct cggcatcgag
    14641 atcaatcgcc gcgataacca ctttaaactg accggccgtc cgatttgcgt caccgctgcg
    14701 gcagacattc tgcgtagcct gtatgtcgat actgccccga tgcgtggtca gattcaggat
    14761 atcgaaccgg aacagatcca ccttgcgatt aaagaagcgc gggtactgga gcaaagcgcg
    14821 gagagcgtgc cggagtacgg caaagcggtc aatatcaaaa ccaaacgcgg cgtaatcaag
    14881 ccgcgcacgc caaaccaggc gcagtacatc gccaatattc tcgaccatga catcaccttc
    14941 ggcgttggcc cggcgggtac gggtaaaacc tacctggcag tggctgcggc agttgatgcc
    15001 ctggagcgtc aggaaattcg ccgtattctg ctgactcgtc cggcggtaga agccggtgag
    15061 aaactgggct tcctgcctgg cgatttaagc cagaaagtag acccgtattt gcgcccactg
    15121 tacgacgcgc tgtttgaaat gctgggcttt gagaaagtcg agaaactgat tgagcgcaac
    15181 gttattgaag tcgcgccgct ggcctatatg cgtggtcgta cgctgaacga cgcgtttatc
    15241 attctcgatg agagccagaa caccaccatc gaacagatga agatgttcct gacccgtatc
    15301 ggttttaact caaaagcggt tatcaccggc gacgtcacac agatcgacct gccgcgtaat
    15361 accaagtcag gcttgcgtca cgccatcgaa gtgctggccg atgttgaaga gatcagcttt
    15421 aacttcttcc acagcgaaga cgtggttcgt cacccggtgg tggcgcgtat cgttaacgct
    15481 tatgaagcct gggaagaagc cgaacaaaaa cgtaaagcgg cgctggcagc agaacgcaag
    15541 cgcgaagaac aggaacaaaa atgagtcagg tgatcctcga tttacaactg gcatgtgaag
    15601 ataattccgg gttaccggaa gagagccagt ttcagacatg gctgaatgcg gtgatcccgc
    15661 agtttcagga agagtcggaa gtgactattc gcgtggtcga taccgccgaa agccacagtc
    15721 tgaatctgac ctatcgcggt aaggataagc cgaccaacgt gctctccttc ccgtttgaag
    15781 tgccgcctgg catggaaatg tcgctactgg gcgatctggt tatctgccgt caggtggttg
    15841 agaaggaagc tcaggagcaa ggcaaaccac tggaggcgca ctgggcgcat atggtggtgc
    15901 acggcagtct gcatttgtta ggttacgatc acatcgaaga tgacgaagca gaagaaatgg
    15961 aagccctcga aacagagatt atgcttgctc tgggctatga ggatccgtac attgccgaga
    16021 aagaataatt tgccaggcat ttgactggca gacgtccccg ccgttggtga ttaacgacgg
    16081 cgttttgatt aactaacatg agaacccata cgacgccatg agcgacgaca attcacacag
    16141 tagtgacacg ataagcaaca agaagggatt tttctccctg ttactcagcc aacttttcca
    16201 cggtgaaccg aaaaaccgtg acgaactgct ggcgctgatc cgtgattccg ggcagaacga
    16261 ccttatcgac gaagatacgc gcgatatgct cgaaggggtg atggacatcg cagaccaacg
    16321 cgtccgcgac atcatgatcc cccgctccca gatgattacc ctgaaacgca accagacact
    16381 ggacgaatgc cttgatgtca tcatcgagtc cgcccactca cgtttcccgg tgattagcga
    16441 agacaaagat cacattgaag ggattctgat ggcgaaagac ttgctgccgt ttatgcgcag
    16501 cgatgctgaa gccttcagca tggacaaagt gttacgtcag gcggttgtcg ttcctgaaag
    16561 taagcgcgta gaccggatgc tgaaagagtt tcgctctcag cgttaccaca tggcgatcgt
    16621 cattgacgaa ttcggtgggg tttccggtct ggtgaccatt gaagacatcc tggaactgat
    16681 tgttggtgag attgaagacg agtatgacga agaagatgat atcgacttcc gtcagttgag
    16741 tcgtcatacc tggaccgtgc gcgcactggc ttccattgaa gacttcaacg aagcgttcgg
    16801 tacccacttt agcgatgaag aggttgacac tatcggtggt ctggtgatgc aggcatttgg
    16861 gcatcttccg gcgcgtggcg aaaccatcga catcgacggt taccagttca aagtggcgat
    16921 ggccgacagt cggcgtatta ttcaggttca tgtcaaaatc ccggatgact caccccagcc
    16981 gaagctggat gaataaaacc gaaactggat agataactac atggcttttg cctcattaat
    17041 tgaacgccag cgcattcgcc tgctgctggc gttattattc ggtgcctgcg gaacgctggc
    17101 cttctctcct tacgatgtct ggcctgcggc gattatttcg ctgatggggc ttcaggcgct
    17161 gacctttaac cgccgtccac tccagtctgc cgctattggc ttttgctggg gatttggtct
    17221 ctttggcagc ggtattaact gggtctatgt cagcatcgcg acctttggcg gaatgcctgg
    17281 cccggttaac atcttcctgg tggtactgct ggcggcgtat ttgtcgctgt ataccggact
    17341 gtttgctggc gtgctgtcgc gtctgtggcc gaaaaccacc tggctgcgcg tggcgattgc
    17401 cgctcctgct ctctggcaag tgaccgagtt tctgcgcggt tgggtgctga ctggcttccc
    17461 gtggttacag ttcggctata gccagattga tggcccgtta aaagggctgg caccgctaat
    17521 gggcgtggaa gccattaact tcctgcttat gatggttagc ggcctgctgg cactggcgtt
    17581 agtcaaacgc aactggcgtc cgctggtggt ggccgtcgtg ctgtttgccc tacccttccc
    17641 gctgcgttac atccagtggt ttaccccgca accggagaaa accattcagg tttcgatggt
    17701 tcagggcgat attccgcaat cgctgaaatg ggacgaaggc cagcttctta atacgctgaa
    17761 gatttactac aacgcaacgg caccgctgat gggcaaatca tcgttgatta tctggccgga
    17821 gtcggcgata accgatctgg aaattaatca gcaaccgttc ctcaaagctc tggacggtga
    17881 gttgcgcgat aaaggtagct cgctggtcac cgggattgtc gacgcgcgtc tcaataagca
    17941 gaaccgctac gatacctaca acaccatcat cacactgggt aaaggcgcac cgtacagcta
    18001 tgaatcagcc gatcgctata acaaaaacca tctggtgccg tttggcgagt ttgtcccgct
    18061 ggagtcgatt ctgcgtccgt tagcaccgtt ctttgatctg ccgatgtcgt cgttcagccg
    18121 tgggccatat atccagccgc cgctgtcggt aaatggtatt gagcttactg cggctatttg
    18181 ctacgagatc attctcggcg agcaagtgcg cgataacttc cgcccggata ccgactatct
    18241 gctgactatc tccaacgatg cgtggtttgg taagtctatt ggtccatggc agcacttcca
    18301 gatggcgcga atgcgtgcgt tggagctggc gcgcccattg ctgcgtagca ccaacaacgg
    18361 tattacggcg gtgattggcc cgcagggtga gattcaggca atgatcccgc agttcacccg
    18421 cgaagtgttg accactaacg tgacgccgac taccggactc acaccgtacg cacgtaccgg
    18481 caactggccg ctgtgggtgc ttacggcgct gtttggtttt gccgctgtgt tgatgagtct
    18541 gcgtcagcga cgtaaacgtt gatgtgaatg atgcgctggc ctgcaaaatt gcatcatttt
    18601 tgcaggctag ataaaccgtt aacaccgcat ccggtatcaa caaaacgtac tttctcattg
    18661 agctgtgggg cgtgattatc atgccccttt tttcttacgg ttcagggata caagccacat
    18721 caccatattg gggatgccga ataattgcct gcggatcaag cgagcgcgtc ctgtccattt
    18781 ggattaaccc gttcttcgcc ataacaaata tctttctacc atccgctgaa aaacgaagat
    18841 gattaacgta gctggcagga taaacgccaa taatctgccc ggcattaata ttgagcagga
    18901 tgacataacc ttgcaggcca tatgacacca acgctaaata ttgaccgtcc gggctaatac
    18961 cctcaacgga ataaacgctc ctgctacacc attgcgtcat aatgctggct tgttgatccc
    19021 ctacgcttat acgtgaaatc ccctggctat cggcaaaaat aatctcgcca ttttttggtc
    19081 ggaatcccat cgcagaaacg acaccacgcg catcacctgt gggaaagtct actttctgat
    19141 gcgtgatggt attgatgcgt acaatgtcgc ctctgaccat accgggtatc aacaatgttt
    19201 tttcatccgg ggaaagtgcc ataacccagg cgcctggttt accgctcgtc cccgtcccgt
    19261 cgtatttctc cagcgggata tccgctacat gctgataagt caccagatca atggctgaca
    19321 cactattact ggtgcgattc atcacccagg cttttgtgcc atcacgcgag aggataagac
    19381 tgtcaggatg tgcaccggtg gtaatcgact gaataatctc ccccgtcgcc acgttaatga
    19441 ccgataacgc attcgcttca aatgaagttg cataaagcaa cgtttcatcc gggcttaacg
    19501 ccagcgatct gacgccctga tctttacagc caccacaatg tttgagtgac ttttctttcg
    19561 ctatgggcgc tgtaaaggta tgcaggattt tcttttgtcc gaggtcgaaa acaacaatac
    19621 tgttcgtgtt ttcaattgcg gcatataacg tattaccatc ccgattgatc gccatatcat
    19681 ggatatcggc aatctcagcg agtaaatcac cactggcctg ctcacgactt accggagcgg
    19741 ataatgtttc cgtgagggcg ttgcgctcct ccactaactg ctgctttttt tgtcgtcgct
    19801 cttgttcaat ctcctgcgga taaaacgctt cacgcaggct ttgcctgact tgtaaaactg
    19861 attcatcaat ctgctgctgc acaagccaga tagccccggt cagaagaaga gtgaccgcaa
    19921 caataatccc gccttccgta acgaatcggt tttgcccaac taaacgcgcg ctcagccaac
    19981 ccaacgcgcc acccgcaatc aggccgccaa tgtggcaagc gttatctatt cctgtttgcc
    20041 gggcaccgta caacagtgtc agcgccacca tacccaacag aggaaatact cgccgctggt
    20101 ttttatggtg tgtgcccgca cctgaagcaa gctgtgttgc tatcgcagcg ccagctattc
    20161 ccataattgc tccggatgcc ccaacgctga tgactatctg ctcactttcg cgtaacgcat
    20221 aacaggcgct gatcagccca ccaaagacgc cagagaatag ccaaacaatc aggagtcgcc
    20281 atttccccag tatccgttcc gccactgccc ccactaccag gagtgcaaac atattcatca
    20341 gtaaatggga aaaactactg tgcagaaaga cactgctaaa taagcgccag ggttcacccg
    20401 acaacgtgag agaggcaacg ttagcgccga gatggatgag tgcggattga tcgacttctt
    20461 cgtaactcat ccattgtgcg aggtaacaaa atatcccaac acagagcgca aaaaggatca
    20521 gggttattgc gggtaattga acatttaacg gcttaaccga agatgcagac ataaggtgat
    20581 tcttccttga aaagactagt aaaaagcatt ttcccgtgtg tagttatcat cccggcaaac
    20641 gtcccacacc gaaaagttaa cactgtccga aatatgactt tttcaaactg aaattacaat
    20701 cgtaattaat gcacccctaa gtattttttg gcatgtaagt tgctttattt actgtgtaag
    20761 caatgaaatc aaccgcgacg caaccgggtt gcaccaccac aaatcagcgg tagcaccaaa
    20821 aaggtgcagt ttaagaattt tgcttcggaa tggtgcggcg catctcgcaa aaacaaacaa
    20881 taaaacagca atacctttac atttatccaa actaaatgtt acctaacaaa cacaacactg
    20941 cacaataaag tcgcagatga taacaacaca aacactcaca acgggtatcc atgcgttttt
    21001 aacgcagaag ataaaggagt tggatatgca attacgtaaa cctgccacag caatcctggc
    21061 cctggcgctt tccgcaggac tggcacaggc agatgacgcc gccccggcag caggcagcac
    21121 gctggacaaa atcgccaaaa acggcgtgat tgtcgtcggt caccgtgaat cttcagtacc
    21181 tttctcttat tacgacaatc agcaaaaagt ggtgggctac tcgcaggatt actccaacgc
    21241 cattgttgaa gcagtgaaaa agaaactcaa caaaccagac ttacaggtga aattgattcc
    21301 gatcacctca caaaaccgta ttccactgct gcaaaacggc actttcgatt ttgaatgcgg
    21361 ttctaccacc aacaacgtcg aacgccaaaa acaggcggct ttctccgaca ctattttcgt
    21421 ggtcggtacg cgcctgctga caaaaaaagg cggcgatatt aaagattttg ccgatctgaa
    21481 agacaaagcc gtcgtagtca cttccggcac cacctctgaa gttttgctca acaaactgaa
    21541 tgaagagcaa aaaatgaaca tgcgcatcat cagcgccaaa gatcacggtg actctttccg
    21601 caccctggaa agcggtcgtg ccgttgcctt tatgatggat gatgccctgc tggccggtga
    21661 acgtgcgaaa gcgaagaaac cagacaactg ggaaatcgtc ggcaagccgc agtctcagga
    21721 agcctacggt tgcatgttgc gtaaagacga tccgcagttc aaaaagctga tggatgacac
    21781 tatcgctcag gtgcagacct ccggtgaagc ggaaaaatgg tttgataagt ggttcaaaaa
    21841 cccaattccg ccgaaaaacc tgaacatgaa tttcgaactg tcagacgaaa tgaaagcact
    21901 gttcaaagaa ccgaatgaca aggcactgaa ctaattacaa gaaccagggg cggaaattcc
    21961 agccctctcg attgttacgt agcacggaca gactatacgc ctggtggtcg ttccccatcg
    22021 ggcctgaaaa ccgcaatacg ctgggtaaca atcttcgagg gtagcagtta acgctgctac
    22081 cctctttttt ctggagtaga tttatgtcta tagactggaa ctggggtatt tttttacaac
    22141 aagccccgtt cggcaacacc acctatcttg gttggatctg gagtggcttt caggtgacga
    22201 tcgctttgtc gatctgcgcc tggattatcg ctttcctcgt cggttcattt ttcggcattt
    22261 tacgtaccgt tccaaaccgt tttctctccg gtctgggtac gttgtatgtc gaactgttcc
    22321 gcaacgtgcc gttgattgtg caattcttta cctggtatct ggtgatcccg gagctgctgc
    22381 cggagaaaat cggcatgtgg tttaaggccg agctggatcc caatattcag tttttccttt
    22441 catccatgct ttgcctgggg ctgtttaccg ccgcccgtgt ttgcgaacag gtacgcgccg
    22501 ctattcagtc gctgccgcgt gggcagaaga atgccgcgct ggcgatgggg ctgacgctac
    22561 cgcaggctta ccgctacgta ctgttgccta acgcttatcg cgttatcgtc ccgccgatga
    22621 cctccgagat gatgaacctg gtgaaaaact ccgccatcgc ctcgactatc ggtctggtag
    22681 atatggcggc gcaggcgggt aaattactcg attactccgc tcacgcctgg gagtcgttta
    22741 ccgccattac gcttgcgtat gtgttgatta acgcttttat catgctggtg atgacgctgg
    22801 ttgaacgtaa agttcgcctg cccggcaaca tggggggcaa ataatgtacg agtttgactg
    22861 gagttccatt gttccttccc tgccgtatct gctggatggg ctggtgatca ccctgaaaat
    22921 caccgtcacg gcagtcgtga ttggtatttt gtggggcacc atgctggcgg tgatgcgctt
    22981 gtccagcttt gcgcccgtag cgtggtttgc caaagcctac gttaacgtat tccgctcgat
    23041 tcctttagtt atggttttgc tgtggtttta cctgattgtg ccgggttttc tgcaaaacgt
    23101 gctgggatta tcgccaaaaa atgatatccg tttaatctcg gcgatggtgg cgttttcgat
    23161 gtttgaagcg gcctactatt cagagattat ccgtgccggt attcaaagta tttcccgtgg
    23221 tcagtcgagc gccgcgctgg cgttggggat gactcactgg cagtcgatga aactgattat
    23281 tctgccgcag gctttccgcg cgatggtgcc gcttctgctc actcagggca tcgtactgtt
    23341 ccaggatacc tcactggtgt atgtgttatc tctggccgat ttcttccgta ccgcctcaac
    23401 cattggtgag cgtgatggta cgcaggtcga gatgatcctg tttgccggat ttgtttattt
    23461 cgttattagc cttagcgcat cgttgttggt cagctacttg aaaagaagga cagcataatg
    23521 attaccctga aaaatgtttc aaaatggtat ggtcactttc aggtgctgac cgactgctca
    23581 accgaagtga aaaaaggcga agtggtggtg gtttgcggcc cgtctggttc cggcaaatca
    23641 acgctgatta aaaccgtcaa cggcctcgaa ccggtgcagc aaggtgaaat taccgtcgat
    23701 ggtatcgtgg ttaacgataa gaaaaccgat ctggcaaagc tgcgttcccg cgtcgggatg
    23761 gtgttccagc atttcgagtt gttcccccat ttgtcgatta ttgaaaacct gaccctggcg
    23821 caggtgaaag tgcttaaacg cgataaagcc cccgctcgtg aaaaagcatt gaaattgctg
    23881 gagcgcgtcg ggctttccgc tcatgccaat aagtttccgg cgcagctttc cggcggtcag
    23941 cagcagcgtg tggcgatcgc tcgcgcattg tgcatggatc ctatcgcgat gctgttcgac
    24001 gaaccgacat cggcgctgga tccggagatg atcaacgaag tgctggacgt gatggtggaa
    24061 ctggcgaacg aaggaatgac catgatggtg gtgacccacg aaatgggctt tgcccgtaaa
    24121 gtggcgaatc gggtgatctt tatggacgag ggtaaaattg tcgaagactc gccgaaagac
    24181 gctttcttcg atgatccgaa atcggaccgc gcaaaagact tcctcgcaaa aatcctgcat
    24241 taatcactct ggcgcgcata cccaagtgcg cgccatctca cgctttatcg tttcgctcct
    24301 cgtatctgtt acatcctggc ggtacccttg tcgcaaagaa gcacacaaca aggagcaaca
    24361 atggcactgc caattctgtt agattgcgac cctggtcatg atgacgctat cgcaatcgtt
    24421 ctcgccctcg cctcaccaga gcttgatgtc aaagcaatta cgtcttccgc cggaaaccag
    24481 acaccagaaa aaaccttacg caatgttctg cgtatgctga ccttgcttaa tcgcaccgat
    24541 attccggtag caagcggtgc ggtaaaacca ttaatgcgtg atttgattat cgcggacaat
    24601 gtgcacggcg aaagcggtct cgacggccct gcattaccgg aaccgacgtt cgcaccgcaa
    24661 aactgtacgg cggtggagct gatggcgaaa acgctgcgtg aaagtgcgga acctgtcacc
    24721 attgtttcta ccggaccgca aacgaacgtt gccttgctgc tcaatagcca cccggaactg
    24781 catagcaaaa ttgcccgtat cgtgattatg ggcggcgcaa tggggcttgg taactggacg
    24841 cctgcggctg aatttaatat ttacgttgac ccggaagcgg cagaaattgt cttccagtca
    24901 ggaattccgg tggtgatggc cggtctggat gttactcaca aagcacaaat ccacgttgaa
    24961 gacactgagc gtttccgcgc gattggcaac cctgtttcaa ccattgttgc cgaactgctg
    25021 gatttcttcc tcgaatatca taaagacgaa aaatggggct ttgtcggcgc accgctgcat
    25081 gacccatgca ccatcgcctg gctgttaaaa ccggagttgt ttaccactgt tgagcgctgg
    25141 gttggcgtgg aaacacaagg gaaatatacc cagggtatga cggttgttga ttattattat
    25201 ctgactggca ataaaccgaa tgccactgta atggtcgatg ttgatcgtca gggctttgtt
    25261 gatttactgg ccgatcgtct gaaattttac gcttaacaca cgtcattgat taagatcacc
    25321 acgcgttacc tgggtggtct taatctgttt atctcttttt ctttcaagat ataaatgcaa
    25381 tggataatgc agaactcgcc attggtatcg atctcggtac taccaatagt ttaattgccg
    25441 tctggaaaga cggtgccgcg caattaattc caaataagtt cggtgaatat ttaacaccat
    25501 ccataattag catggatgaa aataatcata ttttagtcgg aaaaccggct gtatcacggc
    25561 gtacttcgca tccggataaa acggcagcgt tatttaaacg tgcaatgggc agtaatacca
    25621 actggcggtt aggcagcgac acatttaacg cgccagaact gtcctctttg gtattacgct
    25681 cattaaaaga agatgccgaa gaatttctgc aacgtccgat taaagatgtg gtgatctccg
    25741 ttccggctta tttcagcgat gaacaacgca agcatacccg tttagcagcg gagttagccg
    25801 ggttaaatgc ggtacgctta attaatgaac ccacagcagc tgcgatggca tatggcctgc
    25861 atacgcaaca aaatacccgc tcgctggttt ttgatctcgg tggcggcacg tttgacgtca
    25921 cggtgctcga atacgccacg ccggtgattg aagttcacgc ctccgctggc gacaactttc
    25981 ttggcggcga agattttact catatgctgg tggatgaagt tttaaaacgc gccgcagtgg
    26041 ctaaaaacat gctcaacgaa agtgagctgg cagccctgta caccagcgtg gaagcggcaa
    26101 aatgcagcaa tcaattaccg ctgcaaatta gctggcagtg tcaggaagaa acgcgtgagt
    26161 gcgaatttta cgagaacgaa ctggaagatt tgtggttgcc gctgctcaat cgcttgcgag
    26221 taccgattga acaggcgttg cgcgatgcac gtctgaagcc aagtcaaatc gacagtctgg
    26281 tgctggttgg cggcgcatca caaatgccgc tggtgcagcg aatcgccgtg cgtctgtttg
    26341 gcaaattacc gtatcaaagt tacgatccga gcaccattgt cgcgctgggc gcagcaatcc
    26401 aggccgcctg ccgcttacgc agtgaagata ttgaagaggt gatcctcact gatatttgcc
    26461 cttactcgtt gggtgttgaa gttaaccgcc agggcgtttc cggcattttc tcgccgatta
    26521 ttgaacgaaa caccactgta ccggtgtcgc gtgtagaaac ttactcgacc atgcaccggg
    26581 aacaggattc aattacggtt aacgtctatc agggagaaaa ccacaaagtt aaaaataaca
    26641 ttctggtgga atccttcgat gtgccgttga agaaaaccgg ggcttatcag tcgattgata
    26701 ttcgctttag ttatgatatc aacgggttgc ttgaagttga cgtgcttctg gaagacggca
    26761 gcgttaagtc cagagtcatt aatcacagtc ctgtaacatt gagcgcacag cagattgaag
    26821 agagtcggac gcggttatcc gcattgaaaa tttatccgcg cgatatgctc atcaaccgca
    26881 cctttaaggc caaactggaa gagttgtggg cgcgggcgct gggtgacgag cgagaagaga
    26941 tcggccgggt gatcaccgat tttgatgcgg cgttgcagtc aaacgatatg gcccgcgtcg
    27001 atgaagttcg gcgacgggcg agcgattatt tggctattga gatcccttaa acacggctgc
    27061 cggatgcggc ataaacgctg catccggcat cggcgcaaaa aacacatcct cagctaaaca
    27121 acatcgcgat ttttccgaga gcataaccta tcaccagcac cgttaagctg attttgataa
    27181 tgctggtaat gctctgtggt ttttcatcct catcattttt ttcttcgtgg ttttcaggtg
    27241 ttggctcatc gacatcttca tcctccggct cgagtttcac tttcgtcaac agcatccgcg
    27301 tgataatggc ctctaatgga tgagcatctc caccttccag ccttgtatta agacgggcca
    27361 gcatctcttg tttcgggaac gcttccagca caacctgttc cgctacccga tacaaatcca
    27421 gtaacggtga atcttgttct gtctcgctac cgactctcga tttccaccat gcccatgctt
    27481 tgcgcttgaa gaataacgac tcaataaacg attgacctaa cggcgataat tttccgctat
    27541 gtaaaatttc cgcccataac agccgcgtcc gggcgctctc accaggaaca tatttcaacg
    27601 gttgaccttg cgcatctatc atgcttcgcg cttcgataac catcactaat aacgcgaaat
    27661 aatccgggca atgacgcttg ctccactgca acaacaaatt atcagcttgt gtagatgggt
    27721 aactctcccg gtatgcgcag agatcggcaa gcaggctttc cccctcgcca cagtacaacc
    27781 gttgcgcaca ctggtaataa cgggcatctt cgctttctgg attttctgct tgccactgtt
    27841 gggcaacagg aataagttcc gccatacctg ttttcaccga gctgtaccag cgcaacagtt
    27901 tgcgatgtaa cttgacatca tcaggaatga accacggacc ttccattgcc ataaacgcag
    27961 tgacatagtc aggatggtaa cggcagcagc gttccagcgc gaagtaatac tcaacagtct
    28021 ggttctgcaa cgcgacggga tattccagaa ggctaaggaa atcgaaacaa tcaccagcct
    28081 gaatggcctc aagaaaagcc tccctttctt cctcatccat tccttcgctg tcattaaacg
    28141 aatgccagtt caaacgctct gccagcaaag aagcacaatt taatgaaaga tatcgcgctt
    28201 ctatagcgac tgcacacagc ggccagcgta attgatcgac atcctccatg ttccaggtat
    28261 ttaattgctg aataaatttc tgccaggcgg agggctgaaa acgatcactt tcagaatcca
    28321 gtaatgccct gaatgcacgt agtatttcat gttcagcggc ggcatctttt tcttcatcat
    28381 ctgcctcctc gacaggattt accgccagtc gcagcgcctc ttcataggcc tggcgtaatg
    28441 ctttaaaccc ctgcggatcg gtttcgggat gacacaacgg taagcgaaca agataagcct
    28501 ggcggataat gtctatttgc gtcgtgcttt caatttcgag gatttgccaa catgttttca
    28561 taggtcgctc acatccttaa gcgttaccgg gcattcaggc tggacagtta atggctgcca
    28621 gggaagcgtg gcatagaaac ggtcgcttcc cgctgccagc tcttcgaaca tccgactccc
    28681 ggcgctatcg tatttgtaca gggttagcgc ctcgcgtagc gaagcgttgt cttcgcactg
    28741 agaagattgc cagtagagac gccctaacga ataggcggaa aaatagtgca tccagctgtg
    28801 atagtaatgg tgtgctcgta tatagacgcg cgattgcagc cataaactct cgtcttccgt
    28861 cagccacttg ttgagcacac caacccgtga taaaaaaccc atccgcacat aatcccaggc
    28921 tttgattccc ccttccccac aacacatagc ggtttgggca acgaattggg tataaatcaa
    28981 ccctctctcc gagccaccag catttaatgc tttccactct tcaggggaag agcgatgcca
    29041 tgtcagatat aagccagcta aatcattggc atgaccatca tcggtcatct gataaatagt
    29101 ctgaattaaa tcatcacgat tatttattcc ccaggatgat gagagatcga attcttttat
    29161 cccggtatac atttttggcg agtcatgcgc gggcttgcaa ccctgattaa gtatttccat
    29221 gggcgtagaa agcgcaaaaa gaagatattg ttcttcctta ttcatttgtt aataatccct
    29281 taagtgcatt aactgactac ttttttatta ttgatgagta taaacttgac gctttcaaaa
    29341 taaaaagaaa atcgaagcat tcacacatga ataaaaaatt aatgtataca ttcgcaatat
    29401 ttatagttgc agcaataacc tgtattagcc aacccaagaa aacgacgttg cgtgataaag
    29461 ccatggcgaa ttatgccttt gattatttaa gctcaccggg cagtcttcca ttcaccacgg
    29521 cagccacgga gctttccgcg attcatggtc actcaacgtc gcaatatcgc cttggagaat
    29581 tttatcttca tggtagcgac ggtaaaccac tggattatac acaggcgaga tactggtatg
    29641 agcaatcagc ggaacaggaa aatccacgcg cgcaaagtaa actggggtgg atctacctca
    29701 aaggtctggg ggtcaaaccc gatacccgta aagcaattct ctggtataag gaagcagctg
    29761 aacaagggta tgctcatgct caatatactt tgggtttgat ctacagaaat ggctcaggta
    29821 ttaatgttaa ccattatgaa tctcaaaaat ggttaaaact ggccgccaaa caacattaca
    29881 aaaacgcgga aagattactt gccgggcttc ccgcacatta acgtcgactg tcacccgaac
    29941 agatggagta ttttccctat taaaccggca aagataaaaa tgtagaaaat aattttgatg
    30001 acgcccagac agcccggccc accatcgtca acgggcatcg actgcggttg cggctccggt
    30061 tcgacggttt gcttctcggt aaaattcgcc gcctgaatta ataaccgtcg aataattaat
    30121 gcttccagag gacaacgatc ttctgcatca aggcggctca caatcggcat taatgattct
    30181 tctgtcggtt ggctggcctg cactaattgt ttggcaacta gatataatga ccataaggta
    30241 tgttctgtat cacgcgtgag tgagatccgc ggcttacgtc ctttgtgcaa aaccatctcg
    30301 accagagaac gccccagcgc agagagtttt tcatcactga gtatttcgta taaatgaaaa
    30361 cgcgtacgag cgctgtcacc agggacataa agtagcggtt ttccctgatc gttaaccaga
    30421 tcacgcgctt caatcatcat caccactaac gggtaataat cgacccgatg ctgacggcac
    30481 cattgcaaca ttaaagcatc cgcctgggtg gagggatact cgcgccagta gtcacaaagt
    30541 tctgccagca ggctttcgcc ttctccacaa tagacgcgtt gcgcgtattc ataataacgc
    30601 gcatcttcat tatcaggttc agcttcccgc cacgaccggg cgtaatccag aagttcgggg
    30661 atatccagac ggcttgtgct ataccagcgg agtaaatttc tgtgcaaatt tgcatcatcg
    30721 gggataatca ctgcgcgatg ttgcgctaaa tacaatgtca gccattctgg atgcgatgac
    30781 caaatccgag cgaacatttg gtaaaaatca atggtgtcat tttgtacggc aacgggcaga
    30841 tgcagaatgg tctggaagtt aaaaacattc cccttcgcaa tggcatataa aaaggattcc
    30901 agttcttctt cgtctatttc cccgacgttt tcctcctgca accaccgcaa tctttctgct
    30961 aataacacca cgcactcgaa ggataaatgg gcagtgttca tggctattgt gcacagcgac
    31021 cagcgtaatt catcaatatc ttccatcgag caataattta attgctgaat gaatcgctgc
    31081 caggcagagg gcagaaaacg ttcgctatca gaggcgagta acgcacgaaa ggcgagcaga
    31141 atttcatgtt ctgcaacttc atgttcttct ggttgccaaa cagatttagc aggcgactgc
    31201 gcaatccgta gcgcgtcctc atacgcctga cgaagttgtt taaaaccctg cggatcggtt
    31261 tctggatgaa aggacggtaa cagcgccaga taagcgcggc ggataatatc gacgtcagtc
    31321 gtttcctcta tttcgagaat cttccagcaa tttttcatag gtcgctcata tccttaagcg
    31381 tttccgggca tgtggggtag tcagccagtg gttgccaggg taaggtcgcg taatatgcat
    31441 cgtcactggc aaataattga taaaacatat cattgccgga atcgtcgtat tctttacgcg
    31501 ctaagaattc acgtaataaa ggcagatcat catcctcggg agactgccaa tattgccgac
    31561 caaaggtata accggcaaag tattgctgcc agttactata ataacgtaga gcccgtagat
    31621 gaatgcgcga ctggatccac aggctttctt cttcactcaa ccagttatta agtacgccca
    31681 ttcggcttaa aaaacccatc cggacataat cccaggcttt gattccccct tcgccacagc
    31741 attcggcggt gctggcgaca aattgcgcat aagcctgacc ttgctcattt agttcagcaa
    31801 gatagtcacg ccattcacac ggagaataac gaaaccagcg gtgataaagc cctgccaacc
    31861 gagcggcatg accgttatcg atcattcggt gaattgtgcg cagcaggtca tcacggtcat
    31921 caattcccca ggaggaagaa aggtcaaaaa agcgtgtacc taaatacatt ttgggggatg
    31981 aatgcgaagg taaacagcat tcattgcgta tttccatcgg agtggaaagt gcaaacaata
    32041 ttttttgcga ctccatgtcc atataattta tccttaaata ttcattcaat gaatattaac
    32101 cacgttgcga ggctcattta tttatacttt tctgacgcaa cataatacgc ataaaataag
    32161 gcttacgcaa aaatggaaca cataaaaata taatatgctt tatatgcaac cataaggaaa
    32221 tgataatgat ttttacgtca agttgctgcg ataatttatc aatagatgag attatcgaac
    32281 gtgctgaaaa aggcgattgc gaggctcaat atattattgg gttttattat aatcgcgata
    32341 gcgcaattga ctctccggac gacgaaaagg ccttttactg gctgaagctt gccgctgagc
    32401 aaggtcattg tgaagcacaa tattccttag ggcaaaagta taccgaggat aaaagccgtc
    32461 ataaagataa tgggcaagcc atcttttggc tgaaaaaagc tgccctacaa ggccatactt
    32521 tcgcttccaa cgcccttggc tggatacagg atcgtggaga agaccccaac tataaagaag
    32581 cggttgcctg gtatcagata gccgcggaga gcggaatgtc ttatgcgcaa aataatcttg
    32641 ggtggatgta cagaaatggc aacggagtcg cacaagacta tgcgctggca tttttctggt
    32701 acaaacaagc tgcattacaa ggccatagtt acgcgcaaga caacctggcc gatctctata
    32761 aagacggaga aggcgttgct caaaataaga cactcgccgc attctggtat ttgaaaagcg
    32821 cacagcaggg taatcggcat gcccagtttc aaattgcatg ggattataac gctggcgaag
    32881 gggtggacca ggactataag caagcgatgt actggtatct gaaggctgcc gctcaggaaa
    32941 gcgtcggcgc ttacgtcaac atcggttata tgtataaaca tggacaaggc gttgagaaag
    33001 attatcaggc cgcctttgaa tggtttacga aagccgctga atgcgataat gccactgcct
    33061 ggtataacct tgccattatg tatcattacg gagaaggaag acctgtcgat ctccgacagg
    33121 ctctcgatct gtatcgtaaa gctcagtcat ccggtaccag ggatgtcagt caaaaaatcc
    33181 gtgagattga agatttactg taagagataa aaacaagggc cggggaattt tattcggccc
    33241 atatatcttt attgctgtgc gaaatcagac cattaaggct cgaacgggcg tctctggaac
    33301 tggtcatgac cacatttcgg gcatagcgtc agcacttccg gtgtgtagat cgggagatgg
    33361 aagtgacatt tctcgcagac cagatttccc agccctacca cttctccgct gtgataaacc
    33421 ccatgatgat tgaggtcctg gaaaacttcg cgccattcaa gctgcgtttt atcggtgatg
    33481 tctgccagct cctgccacaa gctttcttta atcacccgca taaagacgct gtcagattct
    33541 tctttcaggc tctcttcata gctcatggcg aactcttcca ggtcacgtct gacagctcgc
    33601 gtcagctcat cgacctcggt tcgcgttaac tcccctgttt ttattacgcg ctcgcgcgcc
    33661 tgttccacca gtgcgtcgat atcacgttcg ccattacgca ggcgttcgct cagtgacgcg
    33721 accagttcac ggtaatattg agcaaccttg ttcatcgttt catctcccgg gtcgttaact
    33781 gactataata atagacgttc tttgttcctt gctttgctaa tacgcccaca aactctgtaa
    33841 attaatgtat gaataatccg ggcatcattt caacgtcgag tgcgcgaaag gctgttttga
    33901 cgcggacgtt tgggctatgc tatgcggatc tgaaaaacca cctcaacgct acatttgtag
    33961 ccgtattgaa aacaggacca ctggctgcca tgcaagagca ataccgcccg gaagagatag
    34021 aatccaaagt acagcttcat tgggatgaga agcgcacatt tgaagtaacc gaagacgaga
    34081 gcaaagagaa gtattactgc ctgtctatgc ttccctatcc ttctggtcga ctacacatgg
    34141 gccacgtacg taactacacc atcggtgacg tgatcgcccg ttaccagcgc atgctgggca
    34201 aaaacgttct gcagccgatt ggctgggacg catttggtct gcctgcggaa ggcgcggcgg
    34261 taaaaaacaa caccgctccg gcaccgtgga cgtacgacaa catcgcatac atgaaaaacc
    34321 agctcaaaat gctgggcttt ggttatgact ggagccgcga gctggcaacc tgtacgccgg
    34381 aatactaccg ttgggaacag aaattcttca ccgagctgta taaaaaaggc ctggtatata
    34441 aaaagacttc tgcggtcaac tggtgcccga acgaccagac cgtactggcg aacgaacaag
    34501 ttatcgacgg ctgctgctgg cgctgcgata ccaaagttga acgtaaagag atcccgcagt
    34561 ggtttatcaa aatcaccgct tacgctgacg agctgcttaa cgatctggat aaactggatc
    34621 actggccaga caccgttaaa accatgcagc gtaactggat cggtcgttcc gaaggcgtgg
    34681 aaatcacctt caacgttaac gactatgaca acacgctgac cgtttacact acccgtccgg
    34741 acacctttat gggttgtacc tacctggcgg tagcggcggg tcatccgctg gcgcagaaag
    34801 cggcggaaaa taatcctgaa ctggcggcct ttattgacga atgccgtaac accaaagttg
    34861 ccgaagctga aatggcgacg atggagaaaa aaggcgtcga tactggcttt aaagcggttc
    34921 acccattaac gggcgaagaa attcccgttt gggcagcaaa cttcgtattg atggaatacg
    34981 gcacgggcgc agttatggcg gttccgggtc acgaccagcg cgactacgag tttgcctcta
    35041 aatacggcct gaatatcaaa ccggttatcc tggcagctga cggctctgag ccagatcttt
    35101 ctcagcaagc cctgactgaa aaaggcgtgc tgttcaactc tggcgagttc aacggtcttg
    35161 accatgaagc ggccttcaac gccatcgccg ataaactgac tgcgatgggc gttggcgagc
    35221 gtaaagtgaa ctaccgcctg cgcgactggg gtgtttctcg tcagcgttac tggggcgcgc
    35281 cgattccgat ggtgacgctg gaagacggta ccgtaatgcc gaccccggac gaccagctgc
    35341 cggtgatcct gccggaagat gtggtgatgg acggcattac cagcccgatt aaagcagatc
    35401 cggagtgggc aaaaactacc gttaacggta tgccagcgct gcgtgaaacc gacactttcg
    35461 acacctttat ggagtcctcc tggtactatg cgcgctacac ttgcccggag tacaaagaag
    35521 gtatgctgga ttccaaagcg gctaactact ggctgccggt ggatatctac attggtggta
    35581 tcgaacacgc cattatgcac ctgctctact tccgcttctt ccacaaactg atgcgtgatg
    35641 caggcatggt gaactctgac gaaccagcaa aacagttgct gtgtcagggt atggtgctgg
    35701 cagatgcctt ctactatgtt ggcgaaaacg gcgaacgtaa ctgggtttcc ccggttgatg
    35761 ctatcgttga acgtgacgag aaaggccgta tcgtgaaagc gaaagatgcg gcaggccatg
    35821 aactggttta taccggcatg agcaaaatgt ccaagtcgaa gaacaacggt atcgacccgc
    35881 aggtgatggt tgaacgttac ggcgcggaca ccgttcgtct gtttatgatg tttgcttctc
    35941 cggctgatat gactctcgaa tggcaggaat ccggcgtgga aggggctaac cgcttcctga
    36001 aacgtgtctg gaaactggtt tacgagcaca cagcgaaagg tgatgttgca gcactgaacg
    36061 ttgatgcgct gactgaagat cagaaagcgc tgcgtcgcga tgtgcataaa acgatcgcta
    36121 aagtgaccga tgatatcggc cgtcgtcaga ccttcaacac cgcaattgcg gcgattatgg
    36181 agctgatgaa caaactggcg aaagcaccga ccgatggcga gcaggaccgc gccctgatgc
    36241 aggaagcact gctggccgtt gtccgtatgc ttaacccgtt caccccgcac atctgcttca
    36301 cgctgtggca ggaactgaaa ggcgaaggcg atatcgacaa cgcgccgtgg ccggttgccg
    36361 acgaaaaagc gatggtggaa gactccacgc tggtcgtggt gcaggttaac ggtaaagtcc
    36421 gtgcaaaaat caccgttccg gtggacgcaa cggaagaaca ggttcgcgaa cgtgctggcc
    36481 aggaacatct ggtagcaaaa tatcttgatg gcgttaccgt gcgtaaagtg atttacgtac
    36541 ccggtaaact cctcaatctg gtcgttggct aagcgcggga ggaagcgtgc gatatctggc
    36601 aacattgttg ttatctctgg cggtgttaat caccgccggg tgtggctggc atctgcgtga
    36661 taccacgcag gttccttcca ctatgaaggt catgatcctg gactcaggcg atccgaacgg
    36721 gccattaagc cgtgcggtgc gtaaccagtt acgtctgaat ggtgtcgagt tgcttgataa
    36781 agaaaccacg cgtaaggacg ttccatccct gcgtttgggt aaagtgagca tcgcgaaaga
    36841 taccgcatcg gtattccgta acggtcaaac agcagagtat cagatgatca tgacggtcaa
    36901 tgcgaccgtg ttgatccccg gccgtgacat ctacccgatt agcgccaaag tcttccgttc
    36961 gttcttcgat aacccgcaaa tggcgttagc gaaagataac gaacaagaca tgatcgtaaa
    37021 agagatgtac gaccgtgctg ccgaacagct gattcgtaag ctgccaagca tccgtgctgc
    37081 ggatattcgt tccgacgaag aacagacgtc gaccacaacg gatactccgg caacgcctgc
    37141 acgcgtctct accacgctgg gtaactgatg attcggttgt acccggaaca actccgcgcg
    37201 cagctcaatg aagggctgcg cgcggcgtat cttttacttg gtaacgatcc tctgttattg
    37261 caggaaagcc aggacgctat tcgtcaggta gctgcggtac aaggattcga agaacaccac
    37321 actttttcca ttgatcccaa cactgactgg aatgcgatct tttcgttatg ccaggccatg
    37381 agtctgtttg ccagtcgaca aacgctattg ctgttgttac cagaaaacgg accgaatgcg
    37441 gcgatcaatg aacaacttct cacactcacc ggacttctgc atgacgacct gctgttgatc
    37501 gtccgcggta ataaattaag caaagcgcaa gaaaatgccg cctggtttac tgctcttgcg
    37561 aatcgcagcg tgcaggtgac ctgtcagacg ccggagcagg ctcagcttcc ccgctgggtt
    37621 gctgcgcgcg caaaacagct caacttagaa ctggatgacg cggcgaatca ggtgctctgc
    37681 tactgttatg aaggtaacct gctggcgctg gctcaggcac tggagcgttt atcgctactc
    37741 tggccagacg gcaaactgac attacctcgc gttgaacagg cggtgaatga tgccgcgcat
    37801 ttcacccctt ttcattgggt tgatgctttg ttgatgggaa aaagtaagcg cgcgttgcat
    37861 attcttcagc aactgcgtct ggaaggcagc gaaccggtta ttttgttgcg cacattacaa
    37921 cgtgaactgt tgttactggt taacctgaaa cgccagtctg cccatacgcc actgcgagca
    37981 ttgtttgata agcatcgggt atggcagaac cgccggggca tgatgggcga ggcgttaaat
    38041 cgcttaagcc agccgcagtt acgtcaggcc gtgcaactcc tgacacgaac ggaactcacc
    38101 ctcaaacaag attacggtca gtcagtgtgg gcagagctgg aagggttatc tcttctgttg
    38161 tgccataaac ccctggcgga cgtatttatc gacggttgat atgaaatctt tacaggctct
    38221 gtttggtggc acctttgatc cggtgcacta tggtcatctt aaacccgtgg aaacgctggc
    38281 gaatttgatt ggtctgacgc gggtcacaat catccctaat aatgttcctc cgcatcgtcc
    38341 ccagccggaa gcgaacagcg tacagcgtaa acacatgctt gaactggcga ttgccgacaa
    38401 gccattattt actcttgatg aacgcgagct aaagcgcaat gccccttctt acactgcgca
    38461 aacactgaaa gagtggcggc aggaacaagg gccggacgtg ccgctggcgt ttattatagg
    38521 tcaggattca ttgctgacct ttccgacctg gtacgaatac gaaacgatac tcgacaatgc
    38581 acatttgatc gtctgtcggc gtccaggtta cccacttgaa atggcgcaac cgcaatacca
    38641 gcaatggctg gaagatcatt tgacacataa cccggaagat cttcaccttc agcctgccgg
    38701 taaaatttat ctggctgaaa cgccgtggtt taacatctcg gcgaccatca tccgcgaacg
    38761 tttgcaaaac ggtgaatcgt gtgaggattt attgccggaa ccggtactga cttacattaa
    38821 ccaacaaggc ttgtatcgct gatacctgtc gttacggagg gcatgatgcg actgtggtta
    38881 attcgtcatg gcgaaacgca agcgaatgtc gatggtctgt acagcggtca tgcgcccact
    38941 cccctgacgg cgcgcggtat tgagcaagcg caaaatctgc atacgctgct acatggtgtt
    39001 tcctttgacc tggttttatg cagtgaactg gaacgggcac agcataccgc tcgacgggtt
    39061 ctcagtgatc gccagctccc cgtgcaaatc atccctgaac tcaacgaaat gttttttggc
    39121 gactgggaga tgcgacatca tcgcgacctc atgcaagaag atgccgaaaa ctatagcgcg
    39181 tggtgcaatg actggcagca tgctatcccc acgaacggtg aaggatttca ggcattttca
    39241 caacgtgtgg aacggtttat cgcaaggctt agtgaatttc agcactatca gaatatttta
    39301 gtcgtcagcc atcagggtgt actgagtctg ttaatcgctc gtttaattgg catgcctgcc
    39361 gaggctatgt ggcattttcg cgttgaccag gggtgttgga gcgccattga tatcaaccaa
    39421 aaattcgcga cgctacgcgt cctcaatagc cgtgccatcg gggtcgagaa tgcatgactt
    39481 ttctgttttt ttacgggtaa gccgcaacga ccattgacag ccccgggcag gctgatattc
    39541 tccgcagcca gacttttttc gccagacacg actttgtaga aattgtttta caaaaatggc
    39601 gatgcaatct gcggcgcggg gtgggatgat agcccacttt cgaaagccga ttcggcgaca
    39661 attgtcccga aatcgcctct ggttcaggta tactgacaga ccatttttat ctatttgatt
    39721 cacccagggg gaaaacttgc agggtaaagc actccaggat tttgttatcg acaaaattga
    39781 tgacctcaaa ggtcaggaca tcatcgcctt agacgttcag ggcaaatcca gcatcaccga
    39841 ctgcatgatc atctgtacgg ggacgtccag ccgtcatgtt atgtccattg ctgatcacgt
    39901 tgtgcaggag tctcgcgcag cgggcctgtt accgctcggc gtagaaggtg aaaacagcgc
    39961 cgactggatt gtcgtggatt tgggcgatgt gattgtccat gtcatgcagg aagagagccg
    40021 tcgcctgtat gaactggaaa aactctggag ttaatgcgtg aagctgcaac ttgtcgccgt
    40081 gggaacgaaa atgccggact gggtacaaac cggttttacc gagtacctgc gtcgttttcc
    40141 gaaagatatg cccttcgagc tgattgaaat tccggccgga aaacgcggca agaatgcgga
    40201 catcaagcgc atactcgaca aagagggtga gcagatgttg gcggccgcag gcaaaaaccg
    40261 cattgtcacc ctcgatattc caggcaagcc ctgggatacg ccgcagttag ccgctgagct
    40321 ggaacgctgg aagctggatg gtcgcgacgt cagtctactg attggcgggc ctgaagggtt
    40381 gtcgcctgcc tgtaaagcgg cggcggagca gagctggtcg ctgtcggcgc ttaccctccc
    40441 ccatccgctg gttcgcgtgc tggtcgcaga gagtctgtac cgggcgtgga gcatcaccac
    40501 caaccatcct tatcaccgtg agtgataagt gagctttgag tagaaaacgc agcggatgaa
    40561 actacagaac tcttttcgcg actatacggc agagtccgcg ctgtttgtgc gccgggcgct
    40621 ggtcgccttt ttggggattt tgctgctgac cggcgtgctt atcgccaacc tgtataatct
    40681 gcaaattgtt cgctttaccg actaccagac ccgctctaat gaaaaccgca ttaagctggt
    40741 gcctatcgca cccagccgcg gcattatcta cgaccgtaac ggtatccctc tggctctcaa
    40801 ccgcactatc taccagatag aaatgatgcc ggagaaagtc gataatgtgc agcaaacgct
    40861 ggacgctttg cgcagcgtgg ttgatctgac cgatgatgat attgctgcat tccgaaaaga
    40921 gcgcgcacgt tcacaccgtt tcacctctat tccggtgaaa actaacctga ccgaagtaca
    40981 agtagctcgc tttgccgtca atcagtaccg ttttccgggt gttgaagtta aaggctataa
    41041 acgtcgttac tatccttacg gttcggcgtt gacccacgtc atcggctatg tgtcgaaaat
    41101 caacgataaa gacgtcgaac gcctgaataa tgacggcaaa ctggccaact atgcggcaac
    41161 gcatgatata ggtaagctgg gcattgagcg ttactatgaa gacgtgctgc acggtcagac
    41221 tggttatgaa gaggttgaag ttaacaaccg tgggcgtgtt atccgccagt taaaagaagt
    41281 accaccgcaa gccggacacg atatttacct gacgctggat ctcaaactcc agcaatatat
    41341 tgaaacgctg ctggcgggta gccgcgcagc tgtggtagtc accgatccgc gtacaggtgg
    41401 ggtgttggcg ctggtttcca cgcctagtta tgacccaaac ctgtttgttg acggtatctc
    41461 cagcaaagat tattccgcct tgctgaacga cccgaataca ccgctggtga accgcgccac
    41521 acagggagtt tatcctcccg cgtctacagt taaaccctat gttgcggttt cggcattgag
    41581 tgccggggtg atcacgcgca atacgacgct gtttgaccca ggctggtggc aactgccagg
    41641 ttcagaaaaa cgttatcgtg actggaaaaa atggggccac gggcgtctga atgtcacaag
    41701 atcgctggaa gaatctgcgg ataccttctt ctatcaggtg gcctacgata tgggaatcga
    41761 tcgcctctcc gaatggatgg gtaaattcgg ttatggtcat tacaccggta tcgacctggc
    41821 ggaagaacgt tccggcaaca tgcctacccg cgaatggaaa cagaaacgct ttaaaaaacc
    41881 gtggtatcag ggtgacacca ttccggttgg tatcggtcag ggttactgga cagcgacccc
    41941 aatccagatg agtaaggcac tgatgatcct gattaatgac ggtatcgtga aggttccgca
    42001 tttgctgatg agcaccgccg aagacggcaa acaggtgcca tgggtacaac cgcatgaacc
    42061 gcccgtcggc gatattcatt ccggttactg ggagctggca aaagacggta tgtacggtat
    42121 tgctaaccgc cctaacggta cggcgcataa atactttgcc agcgcaccgt acaaaattgc
    42181 agcaaaatcc ggtacggctc aggtcttcgg cctgaaagcg aacgaaacct ataatgcgca
    42241 caaaattgcc gagcgtttac gtgaccacaa actgatgacc gcctttgcgc catacaacaa
    42301 tccgcaagtg gctgtcgcca tgattctgga gaacggtggc gcgggtccgg cggttggtac
    42361 gctgatgcgc cagatcctcg accacattat gctgggtgat aacaacaccg atctgcctgc
    42421 ggaaaatcca gcggttgccg cagcggagga ccattaatca tgacggataa tccgaataaa
    42481 aaaacattct gggataaagt ccatctcgat cccacaatgc tgctgatctt actggcattg
    42541 ctggtttaca gcgccctggt tatctggagc gccagcggtc aggatattgg catgatggag
    42601 cgtaaaatcg gccagattgc gatgggtctg gtcatcatgg tggtgatggc gcaaattcct
    42661 ccacgcgttt atgaaggctg ggccccctat ctctatatca tctgtattat tttgctggtg
    42721 gcggtagatg ctttcggtgc catctctaaa ggcgctcaac gctggctgga cctcggtatt
    42781 gttcgttttc aaccgtcgga aattgccaag atagccgtac cactgatggt tgcacgcttt
    42841 atcaaccgcg acgtttgccc accttcattg aagaatacag ctatcgcgct ggtgctgata
    42901 tttatgccca cgctgctggt ggctgcacag cctgacctgg gaacatcaat cctcgttgcg
    42961 ctttccggtc tgtttgtact gttcctctct ggccttagct ggcgtctgat tggcgtcgca
    43021 gtagtgctgg tagcggcgtt cattccgatt ctgtggttct tcctgatgca tgattaccag
    43081 cgccagcgcg taatgatgct cctggacccg gaatcagacc cactcggcgc gggctatcac
    43141 attattcagt ctaaaattgc tattggctcc ggcggattac gcggcaaagg ctggctgcat
    43201 ggcactcagt cacagcttga atttctcccc gaacgccata ccgactttat cttcgcggta
    43261 ctggcggaag agctgggatt agtgggcatt ttgattctgc tcgctcttta cattctgctg
    43321 atcatgcgcg ggctgtggat agccgccaga gcgcaaacca cctttggtcg cgtcatggct
    43381 ggcggcttaa tgctgatatt attcgtttat gtcttcgtaa atattggtat ggtaagcggt
    43441 attctgccgg ttgtaggggt tccgctccca ctggtcagtt atggaggatc ggcgctaatt
    43501 gtgctgatgg ctgggttcgg gattgtaatg tcaatccaca cccacaggaa aatgttgtcg
    43561 aaaagcgtgt aagaggtgcg caatgcgtaa gcagtggctc gggatctgca tcgcggcagg
    43621 aatgctcgcg gcatgtacaa gcgatgatgg tcagcaacag acggtaagtg taccgcagcc
    43681 tgcggtatgt aacggcccca tagttgaaat tagcggggcg gacccgcgtt tcgaaccact
    43741 gaacgcgacg gcaaatcagg attaccagcg cgacggtaaa agctacaaaa tcgtgcagga
    43801 tccgtctcga tttagccagg cgggactggc ggcaatctat gatgccgaac ccggcagtaa
    43861 cctgacggcc tctggcgaag ctttcgatcc gacacagctg acggcggccc atccaacgct
    43921 tccgatcccc agctacgcca gaatcactaa cctggctaac gggcgaatga tcgtggtgcg
    43981 cattaatgat cgcggtcctt acggcaacga ccgcgttatt tcgctttctc gcgcggcagc
    44041 tgaccgtctt aacacgtcaa acaacaccaa agttcgtatc gatccgatta ttgtcgccca
    44101 ggatggttcg ctttctggtc ctggtatggc ctgtaccaca gttgctaaac agacttacgc
    44161 cctgcctgca cctcccgatt taagcggcgg cgcgggaaca agttcagtgt ctggcccgca
    44221 gggtgacatt cttccggtca gtaattcgac gctaaaaagc gaagatccga ccggcgcgcc
    44281 ggtaaccagc agcggtttcc tcggtgcacc aacgacctta gcgcctggtg ttctggaagg
    44341 cagcgaacca acacctgcac cacagcccgt tgttacagcc ccctcgacaa cgcctgcaac
    44401 ctcgcctgca atggtgacac cgcaagccgc ctcacaaagc gccagcggca actttatggt
    44461 gcaagtcggg gccgttagcg atcaggctcg tgcgcaacag taccaacagc aactgggaca
    44521 gaagttcggc gtccccggtc gcgtaactca aaatggcgcg gtctggcgga tccagcttgg
    44581 cccattcgcc agcaaagccg aagccagtac cttgcagcaa cgtttgcaaa ccgaagccca
    44641 attacagtca tttattacca ccgcgcagta gcgtaaagca ggcatctgat gtgtcaattt
    44701 ctgtaaatga cgttaacaaa gtcacgcgga aagtcagatg cctgccggta gtgcatttgc
    44761 tatagtaggg cacttttttt aattccatca cggatgtcgt agttcagacc atgaatacca
    44821 ttttttccgc tcgtatcatg aagcgcctgg cgctcaccac ggctctttgc acagccttta
    44881 tctctgctgc acatgccgat gacctgaata tcaaaactat gatcccgggt gtaccgcaga
    44941 tcgatgcgga gtcctacatc ctgattgact ataactccgg caaagtgctc gccgaacaga
    45001 acgcagatgt ccgccgcgat cctgccagcc tgaccaaaat gatgaccagt tacgttatcg
    45061 gccaggcaat gaaagccggt aaatttaaag aaactgattt agtcactatc ggcaacgacg
    45121 catgggccac cggtaacccg gtgtttaaag gttcttcact gatgttcctc aaaccgggca
    45181 tgcaggttcc ggtttctcag ctaatccgcg gtattaacct gcaatcgggt aacgatgctt
    45241 gtgtcgccat ggccgatttt gccgctggta gccaggacgc ttttgttggc ttgatgaaca
    45301 gctacgttaa cgccctgggc ctgaaaaata cccacttcca gacggtacat ggtctggatg
    45361 ctgatggtca gtacagctcc gcgcgagata tggcgctgat cggccaggcg ttgatccgtg
    45421 acgtaccgaa tgaatactcg atctataaag aaaaagaatt tacgtttaac ggtattcgcc
    45481 agctgaaccg taacggcctg ttatgggata acagcctgaa tgtcgacggc atcaaaaccg
    45541 gacacactga caaagcaggt tacaaccttg ttgcttctgc gactgaaggc cagatgcgct
    45601 tgatctctgc ggtgatgggc ggacgtactt ttaaaggccg tgaagccgaa agtaaaaaac
    45661 tgctaacctg gggcttccgt ttcttcgaaa ccgttaaccc actgaaagta ggtaaagagt
    45721 tcgcctctga accggtttgg tttggtgatt ctgatcgcgc ttcgttaggt gttgataaag
    45781 acgtgtatct gaccattccg cgtggccgca tgaaagatct gaaagccagc tatgtgctga
    45841 acagcagtga attgcatgcg ccgctgcaaa agaatcaggt cgtcggtact atcaacttcc
    45901 agcttgatgg caaaacgatc gaacaacgcc cgctggttgt gctgcaagaa atcccggaag
    45961 gcaacttctt cggcaaaatc attgattaca ttaaattaat gttccatcac tggtttggtt
    46021 aaaaatcgaa cacttgaaag tgtaatttcc gtccccatat actaagcatc agtaaaaaac
    46081 tcccgccttc tggcgggagt tgctatttaa ttacgttacg ccggagctga catgaaaacc
    46141 aaacttaacg aactgcttga attccctact ccttttactt acaaagttat ggggcaggcg
    46201 ttacctgagc tggttgatca ggtggttgaa gtggtacagc gccatgcgcc aggtgactac
    46261 accccaacgg taaaaccaag cagcaaaggc aactaccact cggtatctat cactatcaac
    46321 gcgactcata tcgagcaggt tgaaacactg tatgaagaac tgggcaaaat cgatattgtc
    46381 cgcatggttc tgtaactcgc ttctccgtta cccggctcct ggtcgggtaa ctcccctctc
    46441 ctcgctgtga tatacttttc ccccactttt actcattctc cacggagatg ccgttttgta
    46501 tcaggataaa attcttgtcc gccagctcgg tcttcagcct tacgagccaa tctcccaggc
    46561 tatgcatgaa ttcaccgata cccgcgatga aagtaccctt gatgaaatct ggctggtcga
    46621 gcactatccg gtatttaccc aagggcaggc aggaaaagcg gagcacattt taatgccggg
    46681 tgatattccg gtgattaaga gcgatcgcgg tgggcaggtg acttatcacg ggccggggca
    46741 acaggtgatg tatgtgttgc ttaacctgaa acgccgtaaa ctcggtgtgc gtgaactggt
    46801 aaccttgctt gagcaaacag tggtgaatac cctggctgaa ctgggtatag aagcgcatcc
    46861 tcgggctgac gcgcctggtg tctatgtcgg ggaaaagaaa atttgctcac tgggtttacg
    46921 tattcgacgc ggttgttcat tccacggtct ggcattaaac gtcaatatgg atctttcacc
    46981 atttttacgt attaatcctt gtgggtatgc cggaatggaa atggctaaaa tatcacaatg
    47041 gaaacccgaa gcgacgacta ataatattgc accgcgttta ctggaaaata ttttagcgct
    47101 actaaacaat cctgacttcg aatatattac cgcttaattg catacatcaa tggcccaatt
    47161 tacactgggt cattactcat aatacctgct aatgctttac atctccttcg cgtttgtata
    47221 ttttctttat cactagcaga aatgcgatgc tacgccttgc tccgtaactc accccattga
    47281 ttaacttatt gaaatagttg attatggtga gcaaaagcgt tccgttccaa ttagacataa
    47341 gattattgta atttttttta atattatttt tccatgaata aaattggagt aagtgcgtgg
    47401 atagtaataa tcaaattgaa acctgtttaa gcagaaagtc gtcagaaggt aaaccacaaa
    47461 tatttacaac cttacgaaat attgatctta accttctgac tatttttgaa gctgtatatg
    47521 tacataaagg gatcgttaat gcagcgaaag tgcttaatct gacaccctcg gcaatcagtc
    47581 agtctattca gaaactgcgc gttatattcc ctgacccatt gtttattcgc aaaggccagg
    47641 gtgtcactcc taccgcattt gcgatgcatc tacatgagta tatcagtcag ggccttgagt
    47701 ccattcttgg cgcgctggat atcgaaggaa gctatgataa gcaacgaacg ataactattg
    47761 cgaccacccc ctcggtcgga gccctggtcc ttcctgtcat ctatcgggcg attaaatctc
    47821 actatccgca gcttttactg cgcaaccccc ccatcagcga cgcggaaaac caactcagtc
    47881 agtttcaaac cgatctcatc atcgataaca tgttttgcac caatcgtacg gtgcaacatc
    47941 atgttctgtt caccgacaat atggtgttaa tttgccgtga gggaaatcca ctactctctt
    48001 tagaagatga cagagagact atcgacaacg ctgcgcatat actcctgtta ccggaagggc
    48061 aaaatttcag cggtctgcgg cagagagttc aagagatgtt tccggaccgg caaatcagtt
    48121 tcaccagcta caacattttg acaatcgctg cactggttgc caacagtgac atgttagcga
    48181 ttattcccag ccgtttttat aacctgttta gccgttgctg gccgctggaa aaactgcctt
    48241 ttccgtcctt aaatgaggag caaatagatt tctctatcca ctacaacaaa ttcagcctgc
    48301 gtgatcccat cctgcacggg gtaatagatg ttatccgtaa tgcattttga aaaagtattg
    48361 ttacagccag atcacagcga agaacgaaaa aatggcacaa tccaacaaca attttacatt
    48421 ttcgcgaccg ctttggctgc tttcaggtcc gtttcaatga tatactgcca gtcgttaatt
    48481 caaaaatagt tgataattac aacaatctat tgaattgaaa cgctttcctt cgtaattcgc
    48541 aactggaaca cgcacgctat gagtaaaccc attgtgatgg aacgcggtgt taaataccgc
    48601 gatgccgata agatggccct tatcccggtt aaaaacgtgg caacagagcg cgaagccctg
    48661 ctgcgcaagc cggaatggat gaaaatcaag cttccagcgg actctacacg tatccagggc
    48721 atcaaagccg caatgcgcaa aaatggcctg cattctgtct gcgaggaagc ctcctgccct
    48781 aacctggcgg aatgcttcaa ccacggcaca gcaacgttta tgatcctcgg cgctatttgt
    48841 acccgccgtt gtccgttctg tgacgttgcc cacggtcgcc cggtagctcc ggatgccaat
    48901 gaaccagtga aactggcgca aaccattgcc gatatggcgc tgcgttatgt ggttatcacc
    48961 tccgttgacc gtgatgacct gcgcgatggc ggtgcccagc actttgcgga ttgcattact
    49021 gccattcggg aaaaaagccc gcaaatcaaa attgaaactc tggtgcctga tttccgcggt
    49081 cgtatggatc gtgctctgga tattctgacc gccacaccac cagatgtgtt caaccataac
    49141 ctggaaaacg taccgcgtat ttaccgtcag gtacggcctg gtgcagatta caactggtcg
    49201 ctgaagctgc tggaacgctt taaagaagcg catccggaaa tcccgaccaa gtctggtctg
    49261 atggtgggtc tgggtgaaac caatgaagaa attattgagg taatgcgcga cctgcgccgt
    49321 catggtgtga cgatgttaac gctggggcaa tatttgcagc caagccgcca tcacctgccg
    49381 gttcaacgtt acgttagccc ggatgagttc gacgaaatga aagccgaagc gctggcgatg
    49441 ggctttaccc atgctgcatg cggtccgttt gtccgctcgt cttaccacgc cgatttgcag
    49501 gcgaaaggga tggaagttaa gtaatcctgt aataattact tacatctgtc tgataaaaaa
    49561 cccgcttttt gaagcgggtt ttttgtatcg aacaagatat tgagggagcg tcctgctcgc
    49621 cacgtcactc tttatgagag agcttttcag cctgaagatc aacgtctgcg ccttttttcg
    49681 ccgcagcatc gtcatcattc atcgccttct tgaacccttt aatggccgct ccaaggtctc
    49741 cgcccagcgt acgtaacttc ttagtcccaa acagcagaac gaccagcgcc gcaactacca
    49801 gcagtttggt aatactaatc tcacccatag ataccttctt gacatataac cggcaacaga
    49861 acgcgcctta aaaaccagag aatattaacg gtcattcgac gcgcgcacac aatagcaatc
    49921 tgtaacaagg tgaatcaagc gccgagtaaa aaaacatcat aataattgcg gcggcgcaaa
    49981 gcgacggttg tttaagacgg gcagttgcgc gcgcacctga cgcacacgtt cgggcgtcac
    50041 ttccgccata atgagtgaag gcatttctga cgctgccgca atggtgacgc caaagggatc
    50101 tataatccgg ctttgcccga tatttttgtt cccgcactcc cccgccgcca ccatataaca
    50161 ggtggtatcc agcgcacgag cggcaagcaa cgttgaccag tgatgctctt tgagcggccc
    50221 gcgaacccag gcggcaggaa gtaccaggat ttcagctccc tgtaatgcct gtgccagcgc
    50281 cagctctgga aagcgtaagt cataacaggt catcagaccg accttcatcc cttccacctc
    50341 cagtaatgga gctatttcat taccagcatc aacatggcgt gattcctgaa tggcaaatgc
    50401 atcatagaga tgcagtttgg cataacgggc gacgatgttt cctgcctgta gcgccaccag
    50461 catattccat gcgcgccccg gcgttgaagg aacatgaatc gtcagaattg tcgtcatcat
    50521 gttacgttta ctttctcgcc gtaaacgtcc gaggaattcg ccttccagca gctgtgctga
    50581 tttaaccgat agatctgcat catgatcatc acgcgccaac aatgcttccg gcaggacaaa
    50641 cagcgaaacg tcgttttccg ccgcctgcgc catcaacgag gcacaaatct cagcgttctt
    50701 ttcccacaca gatgtaacag caaactgtcc tgcggcaacc agcattgcca cctcctcctg
    50761 tcagagtcgt aaaattcgcc aacggcgatt attcggcgtt acacttatca ctcatacaaa
    50821 tcaaatagca ggattttgca gtgttacaac ttcttttagc agtttttata ggcggtggta
    50881 cgggaagcgt ggcgagatgg ctgttaagta tgcgatttaa cccgctgcat caggcgattc
    50941 cgttggggac gctggctgca aacctgattg gggcattcat cataggaatg ggattcgcct
    51001 ggtttagcag gatgacgaac attgatccag tgtggaaagt attaatcacc accggatttt
    51061 gtggcggtct aacaaccttc tcaacatttt cggcagaagt ggtgtttttg ttacaagagg
    51121 gccgctttgg ctgggcgtta ctgaacgttt tcgtcaacct tctggggtct tttgccatga
    51181 ccgcactggc tttctggctg ttttccgcct caaccgcaca ctaaagacca aaaaaaaccc
    51241 gctgattaag cgggttttga attcttgctg acgtatctta cagagcgatt acgtttgcag
    51301 cagaagggcc tttggcaccg ttagtgattt cgaactctac gcgctgacct tcagcaagag
    51361 ttttaaaacc attagtctgg attgcagaga agtgtacgaa cacgtctttg ctgccgtctt
    51421 ccggagtaat gaaaccgaat cctttggact cattaaacca cttaacgtta cctttaatct
    51481 tagacatcaa aattaccttt acatgaaaaa tagacacaaa tgctgtgtcg gttaccagta
    51541 caccaattgt ggtacgcttt gtccagtgca actttactaa aaagtgataa aagtcgcgtt
    51601 atttttgatg ttaattattt tagtggttga ttttaaagaa tttactaaaa cttcatttgt
    51661 ctcaaaactg aaagcgcatc caggcaaagt acacattgcc attgttgtag gtacccggaa
    51721 tgtaggtcat ctgaaacgtc gcggggccat accccacaga ggccaatggc agtagaaccg
    51781 gaagagggat gtaattccag ttatcgcgcg ccgttacgcc agcggtaaat cccaggccta
    51841 aatgaaaatt ttcatccgcc agcggtcgcc aggtactttc ccatccgtat ccggcaatcg
    51901 gttcccattt gttccacgag tccttaaatg ccatggcata caggccatgc cagtttcctt
    51961 tttcatccca acgcgactga ccaaaaccgc cgccccacgg tcgctcgtta tagcgatcgg
    52021 ttttttcttt gtcataggca aaacgcgcat gccaggtgat ggcaggaata tataaatcat
    52081 aatgttctgg ctgttgccag gtttgtgcaa tattttctct aaacgttgtc atccactcat
    52141 cagcgttagc aaaaacttta ccaacactga ttaactgaat aaaaacaaag aaaaatatag
    52201 cgacatattt actcacgttc atttgtgacc attaaacatt tatcaaaaat ctactactag
    52261 catagcaaag ctacaattaa cataacctta atagccccaa cataaaaaat aatctgaata
    52321 gctgctctat ttatttccgc ttgtttaagt taaatatttc cgcgcatcga ttaaagatga
    52381 tgcgtcgttt tctgcgatgg gaatagtcaa aaaagaaaaa ccaagtcttt tttgatgaca
    52441 aaatgcaatc aaggaaaaat tattttattt tttaacgaga tacaacaatc atcttaacga
    52501 agtatataat atatatcgtc aacccatgct catattagat tattttttga gcgcatggcc
    52561 gcagctaaca ccattgcaat taacaaattt gcatcaatcc accatcaatt tacacacatt
    52621 attatgtgat atttgccaac cgctaaatat gcgttttgtt atctacgtat aaaaacagca
    52681 acttcaatgt cttaatggca gtttttcttg attttaatca gcattcaccg ccaatttatt
    52741 gggcatattt tttccttaat ttttaggaat tttttattat ttactttggg gcctggagac
    52801 aggaaaaatt atgctgacat tcattgaact ccttattggg gttatggtta ttgtgggtgt
    52861 agctcgctac atcattaaag ggtattccgc cactggcgtg ttatttgtcg gtggcctgtt
    52921 attgctgatt atcagtgcca ttatggggca caaagtgtta ccgtccagcc aggcttcaac
    52981 aggctacagc gccacggata tcgttgaata cgttaaaata ttgctaatga gccgcggcgg
    53041 cgacctcggc atgatgatta tgatgctgtg tggctttgcc gcttacatga cccatatcgg
    53101 cgcgaatgat atggtggtca agctggcgtc aaaaccattg cagtatatta actcccctta
    53161 cctgctgatg attgccgcct attttgtcgc ctgtctgatg tctctggccg tctcttccgc
    53221 aaccggtctg ggtgttttgc tgatggcaac cctgtttccg gtgatggtaa acgttggtat
    53281 cagccgtggt gcagctgctg ctatttgtgc ctccccggcg gcgattattc tcgcaccgac
    53341 ttcaggggat gtggtgctgg cggcgcaggc ttccgaaatg tcgctgattg acttcgcctt
    53401 caaaacgacg ctgcctatct caattgctgc aattatcggc atggcgatcg cccacttctt
    53461 ctggcaacgt tatctggata aaaaagagca tatctctcat gaaatgttag atgtcagtga
    53521 aatcaccact actgctcctg cgttttatgc cattttgccg ttcacgccga tcatcggagt
    53581 gctgattttt gacggcaaat ggggtccgca attacacatc atcactattc tggtgatttg
    53641 tatgctgatt gcctccattc tggagttcat ccgcagcttt aatacccaga aagttttctc
    53701 tggtctggaa gtggcttatc gcgggatggc cgatgcgttt gctaacgtgg tgatgctgct
    53761 ggttgccgct ggggtattcg ctcaggggct tagcaccatc ggctttattc aaagtctgat
    53821 ttctatcgcc acctcgtttg gttcggcgag tatcatcctg atgctggtat tagtgatcct
    53881 gacaatgctg gcggcagtca cgaccggttc aggcaatgcg ccgttttatg cgtttgttga
    53941 gatgatcccg aaactggcgc actcttccgg cattaacccg gcgtatttga ctatcccaat
    54001 gctgcaggcg tcaaacctcg gtcgtaccct gtcacccgtt tctggcgtag tcgttgcggt
    54061 tgccgggatg gcgaaaatct caccatttga agtcgtaaaa cgcacctcgg taccggtgct
    54121 tgttgggctg gtgattgtta tcgttgctac agagctgatg gtgccaggaa cggcagccgc
    54181 ggtcacaggc aagtaaatag tcatgccgga ggcaagcttc ctccggcttt atcatgtcac
    54241 ccactgtggt atatgcgttg cggtctgcca actttgccgt gaacaatttc agcaataatc
    54301 agatggcggc tggcgcaata ttcaagataa cgcctggcag tggtgcgact gatggtcagt
    54361 gcctgcgcca ccgtttctgc cgtatgttgg acaccaggct ctttaaacag ttttcgcacc
    54421 gcgtttagcg tcaaggggtc aatgccggtc ggcagttcgt ctttgggttc accgcgagca
    54481 taggcattaa acatctcatc gatttgcttc tggctggcgc tatcaatact ttccagcata
    54541 tgtttacgct ggcggaaacg ggttagcgtt tgccccagcc gttcataggc aatgggctta
    54601 atgagataat caaatacacc acaacgtacg gcttcagaca ccgtttccat atcgctggct
    54661 gcagtggtaa acaccacgtc gccgggataa tgcgcctgca ccagttcatg cagtaaatta
    54721 atccctctac cgtcaggaag atagttatcg agcaagatta gccccggctt aaaacgctcg
    54781 atcatcattc gggcctgcgc caggtttccc gccagtaata tctgactgaa tccgggaatg
    54841 tgacgaatat attccgcatg catctctgcc agcggcgttt cgtcctcaac gatcaatagg
    54901 gttaatggag ctgtcattag gtttcacttt cggaatatag attgaaaata aggtaccgca
    54961 gggatcatta tcttcgagag tgataacacc accgcagcgc gttacgtaac tggcaatcaa
    55021 gtacaaccca atgccatgtt cgccgggctc gtcagcacgc gtactgacac cctgctcaaa
    55081 tattttgtct cgtagagact ctggaacgcc gcagccctga tcggcgactt caatcaccac
    55141 atcatcgcct tcatcgctga ggaataattc aacgatcttg tttccttcat cgctacgcag
    55201 gctggcttcg aaggcgttat caagtaaatt gccaacaatg gcggcaaact cggtgctgtc
    55261 cagtcctggc ggcagttgcg aaagctgact tccggggacg atgaccattt ttagccccag
    55321 ttcgcgggcg cgctgcactt taccaaaaag cagccccgcc acctggcgat cggcaaacgc
    55381 ctcgcgcagg ctatcaataa gctgttgctg ggcctgagac tccccctgca ccatcgccaa
    55441 cacgcgatca tactctttca tctgcaacag accattgagc gtcgacatcc aattgagatg
    55501 ctcgtgtcgc aatgtgcgca ggctctcgac gtattgttta atttgcgtca gttgtgcatt
    55561 gagggtggaa atttcgtctt tactacgaaa gctgataatg gcccccagca aatcatcacc
    55621 tgaacgaata gcttcccgat tggcaataac gctcagaccg ttaaagttcg ccaccacatc
    55681 ctgacgtttt tcatcaatct gttcggtaaa gaaatcggcg ggcctgacca cttcagcaat
    55741 gggtttaccc aaccattgcc gtccggggga actcagaccc agcatctttc ttgcgttacg
    55801 attgatggcg gtaatgtaac catgcggatc caccgcaatg agcccttcat aaaccgaact
    55861 aaacagcgcc tcttgctgac ggaccacgcg tgcgatttgc tttggctcca tgcccatcat
    55921 ttgccgacgg atatgcgcgg ccaggaacca cgatagcaac atcagaatcc ctaacagcac
    55981 gacaaacacg ccagccatcg gtaataaaaa ctcagcccgc cagctatcga ttttactcac
    56041 caggtagcca atcgacacca cgccgatgac ttttccatcg tcatcaaaga ttggcgtttt
    56101 ggcacgcatc gccatgccaa ttgacccttt cccggtgatg aagtagctct cccctttctc
    56161 cagcgcgccc ggtttggtga actgcatagg ataaccaatt ttctccggat taggatggta
    56221 aagacgaatc gagtgccgat cgccaatcac cacataatcg aaatcagtat ctctttgtaa
    56281 tttgtcagcg atggtcgcca gcctcttgta gtcacgcgtt ttcactgcgc tgatgatact
    56341 gtcattagaa gcaataattt ttgcctgatt cattgccatg tcgcgcacat gaagcgttaa
    56401 atagtcctca aaactggccg taaaatattg cgccagggct gcaatgacaa atattgagaa
    56461 caccagaatc agcaaaaaga tacgcagcgg aaatgccagt ctttggaaaa atgcaaactg
    56521 tttattctcg ttaagctgca acattgtttt ccttgcgggt tgtcccgagc ctc
//
LOCUS       DADXDL010000019        55877 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.019, whole genome shotgun sequence.
ACCESSION   DADXDL010000019 DADXDL010000000
VERSION     DADXDL010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 55877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 55877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..55877
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.019"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(98..1375)
                     /locus_tag="IRB70_001457"
     CDS             complement(98..1375)
                     /locus_tag="IRB70_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0631384.1"
                     /translation="MNKIKNYRWHMIALVCFITVINYLDRTALGIAAPTIMETTGITK
                     EQYSWIVSAFQLAYTLGQPVMGFFIDTVGLKLSFAICAAIWGLATMGHALTGTWSGLA
                     FMRALMGFSEASAIPAGVKTASTWFPAKERGVATGVFNMGTSLGAMLAPPLIAWCIMF
                     HSWQFAFIVSGSLALLAALFWFFCYKDPKDAKRLSDEERHYIESGQEQHLKTDKKEKT
                     SIKHILSQRNFWGIGIARFLADPAWGTINFWVPIFFVETLHFSLKEIAMFVWLPFLLG
                     DLGCLASGFVAKFFHDRGVSLINSRRITFTIAAVIMMTIGLVSIVENPYIAVLLISIG
                     AFSHQCLSTVAATLGGDLFKKDEVATAVGMAGACAWSGQLIFNLFIGAFVHIIGFAPF
                     FIALAFFDIIGAIALWTLIKVKDEEPQLQLATH"
     gene            complement(1468..3540)
                     /locus_tag="IRB70_001458"
     CDS             complement(1468..3540)
                     /locus_tag="IRB70_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding protein"
                     /protein_id="HBC0631385.1"
                     /translation="MSQLDDTILDALTHVTFPKGFAQAEPAWVVTVDGVDYPLWQTDA
                     LVVGSGAAGLRAAVELKRRQQNVLIATAGLYMGTSACSGSDKQTLFTAATAGNGDNFT
                     KLAEALASGGAMDHDTAYVEAVGSLHTLGGLQYLGLELPEDRYGAILRYQTDHDEAGR
                     ATSCGPRTSRLMVKVLLEEVQRLAIPVLTSATVIKLLHQRDENGEDRVAGAILATGHR
                     AHNPWGLAIVTAPNVVLATGGPGELYRDSVYPHKCFGSLGLALEEGLTLTNLTESQFG
                     IGTPRSTFPWNLSGTYVQVIPYIYSVDAEGNEYNFLADYYRTTQELASNIFRKGYQWP
                     FHATRVMDFGSSLLDMAVAQEQQYGRQVFMDFNRNPVAVPGDLPFSLDRLDDDVRAYL
                     ENNDALAPSPIERLQRMNPLSISLYKMHGYDLTTQPLQFAMNNQHMNGGIEVDIWGQT
                     SLPGCFAVGEVAGTHGVTRPGGAALNAGQVFAVRLARFIGCTQKRNIDGDIAQLAAPA
                     LASIREIITQAHDNGTGMPLSVVREKIQARMSDHAGFICHADKVRRATRDALLLNEFV
                     QRHGLAIKHVGEVAELFMWRHMTLTSAAVLTQLTHYIDAGGGSRGARIVIDPQGKCLP
                     QTRRGAKEEWRFRSELAEDKNHKLTIQYSQGSFITEVKSLRMQPCINGIYFEKNWPDF
                     LNGDIYTQ"
     gene            complement(3537..5078)
                     /locus_tag="IRB70_001459"
     CDS             complement(3537..5078)
                     /locus_tag="IRB70_001459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001226973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA--acetoacetyl-CoA transferase"
                     /protein_id="HBC0631386.1"
                     /translation="MRKITTAEALAAQIQDGATIAISGNGGGMVEADHILAAIEARFL
                     QTGHPRDLTLIHSLGIGDRDCKGTNRFAHAEMLKRIIAGHFTWSPKMQALVKNNTIEA
                     YCFPGGVIQALLREIGAGRPGLFTHVGLGSFVDPRNGGGKSNECTTDDLVELIEIDGE
                     TKLRYRPFKVDYAILRGTYADPRGNVSLEEEAIDMDSYSMALAAHNSGGKVFVQVRDV
                     LEAGAIEPRRVKLPGILVDGIVEHREQPQTYLGGYDLTISGQHRRLSSNDAIELVSHP
                     VRRLIARRAARELVAGASTNFGFGIPGGIPGVALREGVPYQSLWLSVEQGVHNGMMLD
                     DALFGCARNADAIIPSLDQFEFYSGGGIDITFLGMGEMDQYGNVNVSHLNGNLIGPGG
                     FLEIAQNARKVVFCGTFDAKGSKIDVTPDGLHIAQSGQIPKLVTQVEKITFSAAYAQQ
                     SGQEVLYITERAVFQLTAEGVELIEIAPGVEIERDILPYMAFRPIIKHPRLMESSLFT
                     PMEDA"
     gene            complement(5088..5864)
                     /locus_tag="IRB70_001460"
     CDS             complement(5088..5864)
                     /locus_tag="IRB70_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001283531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-CoA hydratase/isomerase family protein"
                     /protein_id="HBC0631387.1"
                     /translation="MSDQPVLFSRAAASCRLTLNREDKCHAINEEMIESLDHYLNEIE
                     NDTTLRLVELTATGDKFFCAGGDIKSWSAYSPLDMGRKWIKRGNDVFNRLRNLPQLTV
                     ANLNGHTIGGGIELALCCDIRIARPGAKFSNPEVMLGMVPGWMGIERVLNQVGPVVGR
                     QMLMLGKRLTAQEAQAANLIDEVVEKEQVESWMANQLAQLEKCGPVALAHIKQLILAL
                     ENKHADYPHQLLAGLMSATQDCQQATRAFAEKSSVSFHNQ"
     gene            complement(5874..6716)
                     /locus_tag="IRB70_001461"
     CDS             complement(5874..6716)
                     /locus_tag="IRB70_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBC0631388.1"
                     /translation="MRDLLQRPDLFSINTATLGYKTPLPAIIDACAARGIGAIAPWRR
                     ELQGEDLQQIARQLAASNINVSGLCRSTYYTAPTLAERKLAIDDNRRALDDAAVLNAA
                     CYMQVVGGLPMGTKDLYEAREQVKQGIRQLLPHSKDVGVPIALEPLHPMTAADRSCLC
                     TLRQALDWCDELDPDGEFGLGVAVDVYHVWWDPDLASQILRAGKRILAFHVSDWLVPT
                     TDLVNDRGMPGDGVINIPSIRRLVENAGFNGAIELEIFSPYWWQQDIDSTLDISVDRI
                     AHYC"
     gene            complement(6726..7517)
                     /locus_tag="IRB70_001462"
     CDS             complement(6726..7517)
                     /locus_tag="IRB70_001462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709993.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-ketoacyl-ACP reductase"
                     /protein_id="HBC0631389.1"
                     /translation="MKSTRPVAVITGAARGIGKGCALELARGGFNLLINDRPDADSVE
                     KLHATQQECLAEGVEVICFPADVGDLSLHEEMLDAAQNQWGRLDCLLNNAGISVKKRG
                     DLLDLEPDSFDQNIAINTRAPFFLAQAFSKRLLAQPKPEAELPHRSIIFVSSINAIML
                     AMNRGEYTIAKTAVSAAARLFAARLCNEQIGVYEVRPGLIKTDMTIPATAYYDELIAK
                     GLVPWGRWGYPADIASTVRAMAEGKLIYTCGQAVAIDGGLSMPRF"
     gene            7730..8377
                     /locus_tag="IRB70_001463"
     CDS             7730..8377
                     /locus_tag="IRB70_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709992.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBC0631390.1"
                     /translation="MYLDTSNVQSLKEKLLLCAVNEFAEYGYEGARVDNIVKAAGCSK
                     QTVYHHFGNKENLFIEVLEYTWNDIRQKEKALDFSDLPPQKAIEKIIDFTWDYYISNP
                     WFLKIVHSENQSKGVHYAKSQRLLEINHAHLQLMESLLDEGKKHNIFKPDIDPLQVNI
                     NIAALGGYYLINQHTLGLVYHISMVSPQALEARRKVIKETILSWLLVDPSSTARE"
     gene            complement(8361..8999)
                     /gene="ytfB"
                     /locus_tag="IRB70_001464"
     CDS             complement(8361..8999)
                     /gene="ytfB"
                     /locus_tag="IRB70_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418627.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein YtfB"
                     /protein_id="HBC0631391.1"
                     /translation="MPGRFELKPTLEKVWHAPDNFRFMDPLPPMHRRGIIIAAIVLVV
                     GFLLPSDDTPNAPVVTREAQLDIQSQSQPPTEEQLRAQLVTPQNDPDQVAPVAPEPIQ
                     EGQPEEQPQTTHTQPFQPDSGIDNQWRSYRVEPGKTMAQLFRDHGLPATDVYAMAQVE
                     GADKPLSNLQNGQMVKIRQNASGVVTGLTIDTGNNQQVLFTRQPDGSFIRAR"
     gene            9217..9837
                     /gene="fklB"
                     /locus_tag="IRB70_001465"
     CDS             9217..9837
                     /gene="fklB"
                     /locus_tag="IRB70_001465"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015742582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBC0631392.1"
                     /translation="MTTPTFDTIEAQASYGIGLQVGQQLSESGLEGLLPEALVAGIAD
                     ALEGKHPAVPVDVVHRALREIHERADAVRRQRFQAMAAEGVKYLEENAKKEGVNSTES
                     GLQFRVINQGEGAIPARTDRVRVHYTGKLIDGTVFDSSVARGEPAEFPVNGVIPGWIE
                     ALTLMPVGSKWELTIPQELAYGERGAGASIPPFSTLVFEVELLEIL"
     gene            10146..11558
                     /gene="cycA"
                     /locus_tag="IRB70_001466"
                     /gene_synonym="dagA"
     CDS             10146..11558
                     /gene="cycA"
                     /locus_tag="IRB70_001466"
                     /gene_synonym="dagA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine/D-alanine/glycine transporter"
                     /protein_id="HBC0631393.1"
                     /translation="MVDQVKVVADDQAPAEQSLRRNLTNRHIQLIAIGGAIGTGLFMG
                     SGKTISLAGPSIIFVYMIIGFMLFFVMRAMGELLLSNLEYKSFSDFASDLLGPWAGYF
                     TGWTYWFCWVVTGMADVVAITAYAQFWFPGLSDWVASLSVIILLLVLNLATVKMFGEM
                     EFWFAMIKIVAIVSLIVVGLVMVAMHFQSPTGVEASFAHLWNDGGWFPKGLSGFFAGF
                     QIAVFAFVGIELVGTTAAETKDPEKSLPRAINSIPIRIIMFYVFSLIVIMSVTPWSSV
                     VPEKSPFVELFVLVGLPAAASVINFVVLTSAASSANSGVFSTSRMLFGLAQEGVAPKA
                     FAKLSKRAVPAKGLTFSCICLLGGVVMLYVNPSVIGAFTMITTVSAILFMFVWTIILC
                     SYLVYRKQRPHLHEKSIYKMPLGKLMCWVCMAFFVFVLVLLTLEDDTRQALLVTPLWF
                     IALGLGWLFIGKKRAAELRK"
     gene            complement(11603..12265)
                     /gene="ytfE"
                     /locus_tag="IRB70_001467"
     CDS             complement(11603..12265)
                     /gene="ytfE"
                     /locus_tag="IRB70_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster repair protein YtfE"
                     /protein_id="HBC0631394.1"
                     /translation="MAYRDQPLGELALSIPRASALFRKYDMDYCCGGKQTLARAAARK
                     ELDVDVIEAELAKLAEQPIEKDWRSAPLAEIIDHIIVRYHDRHREQLPELILQATKVE
                     RVHADKPSVPKGLTKYLTMLHEELSSHMMKEEQILFPMIKQGMGSQAMGPISVMESEH
                     DEAGELLEVIKHTTNNVTPPPEACTTWKAMYNGINELIDDLMEHISLENNVLFPRALA
                     GE"
     gene            complement(12373..13338)
                     /locus_tag="IRB70_001468"
     CDS             complement(12373..13338)
                     /locus_tag="IRB70_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBC0631395.1"
                     /translation="MISGVLYALLAGLMWGLIFVGPLIVPEYPAMLQSMGRYLALGLI
                     ALPIAWLGRVRLRQLARRDWLTALMLTMMGNLIYYFCLASAIQRTGAPVSTMIIGTLP
                     VVIPVFANLLYSQRDGKLAWGKLAPALICIGIGLACVNIAELNHGLPDFDWARYTSGI
                     VLALVSVVCWAWYALRNARWLRENPDKHPMMWATAQALVTLPVSLIGYLVACYWLNMQ
                     TPDFSLPFGPRPLVFISLMVAIAVLCSWVGALCWNVASQRLPTVILGPLIVFETLAGL
                     LYTFLLRQQMPPLMTLSGIALLVIGVVIAVRAKPEKPLTESVSES"
     gene            complement(13446..14306)
                     /gene="qorB"
                     /locus_tag="IRB70_001469"
     CDS             complement(13446..14306)
                     /gene="qorB"
                     /locus_tag="IRB70_001469"
                     /EC_number="1.6.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H:quinone oxidoreductase"
                     /protein_id="HBC0631396.1"
                     /translation="MIAITGATGQLGHYVIESLMKTVPASQIVAIVRNPAKAQALTAQ
                     GITVRQADYGDEAALTSALQGVEKLLLISSSEVGQRATQHRNVINAAKAADVKFIAYT
                     SLLHADTSPLGLADEHIETEKMLADSGIVYTLLRNGWYSENYLASAPAALEHGVFIGA
                     AGDGKIASATRADYAVAAARVISEAGHEGKVYELAGDSAWTLTQLAAELTKQSGKPIT
                     YQNLSEADFAAALKSVGLPDGLADMLADSDVGASKGGLFDDSKTLSKLIGRPTTTLAE
                     SVSHLFNVNN"
     gene            14395..14775
                     /locus_tag="IRB70_001470"
     CDS             14395..14775
                     /locus_tag="IRB70_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418633.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBC0631397.1"
                     /translation="MSQVSLSQQLKEGNLFAEQCPSREVLKHVTSRWGVLILVALREG
                     THRFSDLRRKMGGVSEKMLAQSLQALEQDGFLNRISYPVVPPHVEYSLTPLGEQVSEK
                     VAALADWIELNLPEVLAVRDERAA"
     gene            complement(14904..16847)
                     /gene="cpdB"
                     /locus_tag="IRB70_001471"
     CDS             complement(14904..16847)
                     /gene="cpdB"
                     /locus_tag="IRB70_001471"
                     /EC_number="3.1.4.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2',3'-cyclic-nucleotide 2'-phosphodiesterase"
                     /protein_id="HBC0631398.1"
                     /translation="MIKFSATLLATLIAASVNAATVDLRIMETTDLHSNMMDFDYYKD
                     TATEKFGLVRTASLINDARNEVKNSVLVDNGDLIQGSPLADYMSAKGLKAGDIHPVYK
                     ALNTLDYTVGTLGNHEFNYGLDYLKNALAGAKFPYVNANVIDARTKQPMFTPYLIKDT
                     EVVDKDGKKQTLKIGYIGVVPPQIMGWDKANLSGKVTVNDITETVRKYVPEMREKGAD
                     VVVVLAHSGLSADPYKVMAENSVYYLSEIPGVNAIMFGHAHAVFPGKDFADIEGADIA
                     KGTLNGVPAVMPGMWGDHLGVVDLQLSNDSGKWQVTQAKAEARPIYDIANKKSLAAED
                     SKLVETLKADHDATRQFVSKPIGKSADNMYSYLALVQDDPTVQVVNNAQKAYVEHYIQ
                     GDPDLAKLPVLSAAAPFKVGGRKNDPASYVEVEKGQLTFRNAADLYLYPNTLIVVKAS
                     GKEVKEWLECSAGQFNQIDPNSTKPQSLINWDGFRTYNFDVIDGVNYQIDVTQPARYD
                     GECQMVNANAERIKNLTFNGKPIDPNAMFLVATNNYRAYGGKFAGTGDSHIAFASPDE
                     NRSVLAAWIADESKRAGEIHPAADNNWRLAPIAGDKKLDIRFETSPSDKAAAFIKEKG
                     QYPMKKVATDDIGFAIYQVDLSK"
     gene            17037..17777
                     /gene="cysQ"
                     /locus_tag="IRB70_001472"
     CDS             17037..17777
                     /gene="cysQ"
                     /locus_tag="IRB70_001472"
                     /EC_number="3.1.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'(2'),5'-bisphosphate nucleotidase CysQ"
                     /protein_id="HBC0631399.1"
                     /translation="MLDQVCQLARNAGDAIMQVYDGTKPMDVVSKADNSPVTAADIAA
                     HTVIMDGLRTLTPDIPVLSEEDPPGWEVRQHWQRYWLVDPLDGTKEFIKRNGEFTVNI
                     ALIDHGKPILGVVYAPVMNVMYSAAEGKAWKEECGVRKQIQVRDARPPLVVISRSHAD
                     AELKEYLQQLGEHQTTSIGSSLKFCLVAEGQAQLYPRFGPTNIWDTAAGHAVAAAAGA
                     HVHDWQGKPLDYTPRESFLNPGFRVSIY"
     gene            complement(17767..18324)
                     /locus_tag="IRB70_001473"
     CDS             complement(17767..18324)
                     /locus_tag="IRB70_001473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HBC0631400.1"
                     /translation="MTLRKILALTCLLLPMMASAHQFETGQRVPPIGITDRGELVLDK
                     DQFSYKTWNSAQLVGKVRVLQHIAGRTSAKEKNATLIEAIKSAKLPHDRYQTTTIVNT
                     DDAIPGSGMFVRSSLESNKKLYPWSQFIVDSNGVARGAWQLDEKSSAVVVLDKDGRVQ
                     WAKDGALTQEEVQQVMDLLHKLINK"
     gene            18649..18855
                     /locus_tag="IRB70_001474"
     CDS             18649..18855
                     /locus_tag="IRB70_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1107 domain-containing protein"
                     /protein_id="HBC0631401.1"
                     /translation="MKIFQRYNPLQVAKYVKILFRGRLYIKDVGAFEFDKGKILIPKV
                     KDKLHLSVMSEVNRQVMRLQTEMA"
     gene            complement(18916..20259)
                     /locus_tag="IRB70_001475"
     CDS             complement(18916..20259)
                     /locus_tag="IRB70_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBC0631402.1"
                     /translation="MLNSILVILCLIAVSAFFSMSEISLAASRKIKLKLLADEGNINA
                     QRVLNMQENPGMFFTVVQIGLNAVAILGGIVGDAAFSPAFHSLFSRYMSAELSEQLSF
                     ILSFSLVTGMFILFADLTPKRIGMIAPEAVALRIINPMRFCLYVCTPLVWFFNGLANI
                     IFRIFKLPMVRKDDITSDDIYAVVEAGALAGVLRKQEHELIENVFELESRTVPSSMTP
                     RENVIWFDLHEDEQSLKNKVAEHPHSKFLVCNEDIDHIIGYVDSKDLLNRVLANQSLA
                     LNSGVQIRNTLIVPDTLTLSEALESFKTAGEDFAVIMNEYALVVGIITLNDVMTTLMG
                     DLVGQGLEEQIVARDENSWLIDGGTPIDDVMRVLDIDEFPQSGNYETIGGFMMFMLRK
                     IPKRTDSVKFAGYKFEVVDIDNYRIDQLLVTRIDSKATALSPKLPDAKDKEESVA"
     gene            complement(20582..21220)
                     /gene="msrA"
                     /locus_tag="IRB70_001476"
     CDS             complement(20582..21220)
                     /gene="msrA"
                     /locus_tag="IRB70_001476"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBC0631403.1"
                     /translation="MSLFDKKHLVSPADALPGRNTPMPVATLHAVNGHSMTNVPDGME
                     IAIFAMGCFWGVERLFWQLPGVYSTAAGYTGGYTPNPTYREVCSGDTGHAEAVRIVYD
                     PSVISYEQLLQVFWENHDPAQGMRQGNDHGTQYRSAIYPLTPEQDAAARASLERFQAA
                     MLAADDDRRITTEIANATPFYYAEDDHQQYLHKNPYGYCGIGGIGVCLPPEA"
     gene            21426..23159
                     /gene="tamA"
                     /locus_tag="IRB70_001477"
     CDS             21426..23159
                     /gene="tamA"
                     /locus_tag="IRB70_001477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamA"
                     /protein_id="HBC0631404.1"
                     /translation="MRYIRQLCCVSLLCLSGSAVAANVRLQVEGLSGQLEKNVRAQLS
                     TIESDEVTPDRRFRARVDDAIREGLKALGYYQPTIEFDLRPPPKKGRQVLIAKVTPGV
                     PVLIGGTDVVLRGGARTDKDYLKLLDTRPAIGTVLNQGDYENFKKSLTSIALRKGYFD
                     SEFTKAQLGIALGLHKAFWDIDYNSGERYRFGHVTFEGSQIRDEYLQNLVPFKEGDEY
                     ESKDLAELNRRLSATGWFNSVVVAPQFDKSRETKVLPLTGVVSPRTENTIETGVGYST
                     DVGPRVKATWKKPWMNSYGHSLTTSTSISAPEQILDFSYKMPLLKNPLEQYYLVQGGF
                     KRTDLNDTESDSTTLVASRYWDLSSGWQRAINLRWSLDHFTQGEITNTTMLFYPGVMI
                     SRTRSRGGLMPTWGDSQRYSIDYSNTAWGSDVDFSVFQAQNVWIRTLYDRHRFVTRGT
                     LGWIETGDFDKVPPDLRFFAGGDRSIRGYKYKSIAPKYANGDLKGASKLITGSLEYQY
                     NVTGKWWGAVFVDSGEAVSDIRRSDFKTGTGVGVRWESPVGPIKLDFAVPVADKDEHG
                     LQFYIGLGPEL"
     gene            23156..26935
                     /gene="tamB"
                     /locus_tag="IRB70_001478"
     CDS             23156..26935
                     /gene="tamB"
                     /locus_tag="IRB70_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter assembly complex protein TamB"
                     /protein_id="HBC0631405.1"
                     /translation="MSLWKKISLGVVIVILLLLGSVAFLVGTTSGLHLVFKAADRWVP
                     GLDIGKVTGGWRDLTLSDVRYEQPGVAVKAGNLHLAVGLECLWNSSVCINDLALKDIQ
                     VNIDSKKMPPSEQVEEEEDSGPLDLSTPYPITLTRVALDNVNIKIDDTTVSVMDFTSG
                     LNWQEKTLTLKPTSLKGLLIALPKVAEVAQEEVVEPKIENPQPDEKPLGETLKDLFSR
                     PVLPEMTDVHLPLNLNIEEFKGEQLRVTGDTDITVSTMLLKVSSIDGNTKLDALDIDS
                     SQGIVNASGTAQLSDNWPVDITLNSTLNVEPLKGEKVKLKVGGALREQLEIGVNLSGP
                     VDMDLRAQTRLAEAGLPLNVEVNSKQLYWPFTGEKQYQADDLKLKLTGKMTDYTLSMR
                     TAVKGQEIPPATITLDAKGNEQQVNLDKLTVAALEGKTELKALLDWQQAISWRGELTL
                     NGINTAKEFPEWPSKLNGLIKTRGSLYGGTWQMEVPELKLTGNVKQNKVNVDGTLKGN
                     SYMQWMIPGLHLELGPNSAEVKGELGVKDLNLDATINAPGLDNALPGLGGTAKGLVKV
                     RGTVEAPQLLADITARGLRWQELSVAQVRVEGDIKSTDQIAGKLDVRVEQISQPDVSI
                     NLVTLNAKGSEQQHELQLRIQGEPVSGQLNLAGSFDRKEERWKGTLSNTRFQTPVGPW
                     SLTRDIALDYRNKEQKISIGPHCWLNPNAELCVPQTIDAGAEGRAVVNLNRFDLAMLK
                     PFMPETTQASGIFTGKADVAWDTTKEGLPQGSITLSGRNVQVTQTVNDAALPVAFQTL
                     NLTAELRNNRAELGWTIRLTNNGQFDGQVQVADPQGRRNLGGNVNIRNFNLAMINPIF
                     TRGEKAAGMVSANLRLGGDVQSPQLFGLLQVTGVDIDGNFMPFDMQPSQLAVNFNGMR
                     STLAGTVRTQQGEIYLNGDADWSQIENWRARVTAKGSKVRITVPPMVRMDVSPDVVFE
                     ATPNLFTLDGRVDVPWARIVVHELPESAVGVSSDVVMLNDNLQPEEAKTASIPINSNL
                     IVHVGNNVRIDAFGLKARLTGDLNVVQDKQGLGLNGQINIPEGRFHAYGQDLIVRKGE
                     LLFSGPPDQPYLNIEAIRNPDATEDDVIAGVRVTGLADEPKAEIFSDPAMSQQAALSY
                     LLRGQGLESDQSDSAAMTSMLIGLGVAQSGQIVGKIGETFGVSNLALDTQGVGDSSQV
                     VVSGYVLPGLQVKYGVGIFDSIATLTLRYRLMPKLYLEAVSGVDQALDLLYQFEF"
     gene            26938..27279
                     /locus_tag="IRB70_001479"
     CDS             26938..27279
                     /locus_tag="IRB70_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamylcyclotransferase"
                     /protein_id="HBC0631406.1"
                     /translation="MRIFVYGSLRHKQGNSHWMTNAQLLGDFSIDNYQLYSLGHYPGA
                     VPGNGTVHGEVYRIDNATLAELDALRTRGGEYARQLIQTPYGSAWMYVYQRPVDGLKL
                     IESGDWLDRDK"
     gene            27491..27742
                     /gene="chpS"
                     /locus_tag="IRB70_001480"
     CDS             27491..27742
                     /gene="chpS"
                     /locus_tag="IRB70_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin ChpS"
                     /protein_id="HBC0631407.1"
                     /translation="MRITIKRWGNSSGMVIPNVVMKELNLRPGQSVEAQVSNNQLILT
                     PISRRYSLDELLAQCDMNATELSEQDVWGKSTPAGDEIW"
     gene            27736..28086
                     /gene="chpB"
                     /locus_tag="IRB70_001481"
     CDS             27736..28086
                     /gene="chpB"
                     /locus_tag="IRB70_001481"
                     /EC_number="4.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease toxin ChpB"
                     /protein_id="HBC0631408.1"
                     /translation="MVKKSEFERGDIVLVGFDPASGHEQQGAGRPALVLSVQAFNQLG
                     MTLVAPITQGGNFARYAGFSVPLHCEEGDVHGVVLVNQVRMMDLRARLAKRIGLAAGE
                     VVEEALLRLQAVVE"
     gene            complement(28165..28695)
                     /gene="ppa"
                     /locus_tag="IRB70_001482"
     CDS             complement(28165..28695)
                     /gene="ppa"
                     /locus_tag="IRB70_001482"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001739810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic diphosphatase"
                     /protein_id="HBC0631409.1"
                     /translation="MSLLNVPAGKDLPEDIYVVIEIPANADPIKYEIDKESGALFVDR
                     FMSTAMFYPCNYGYINHTLSLDGDPVDVLVPTPYPLQPGSVIRCRPVGVLKMTDEAGE
                     DAKLVAVPHSKLSKEYDHIKDVNDLPELLKAQIAHFFEHYKDLEKGKWVKVEGWENAE
                     AAKAEIVASFERAKNK"
     gene            29005..29961
                     /gene="ytfQ"
                     /locus_tag="IRB70_001483"
     CDS             29005..29961
                     /gene="ytfQ"
                     /locus_tag="IRB70_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactofuranose ABC transporter
                     substrate-binding protein YtfQ"
                     /protein_id="HBC0631410.1"
                     /translation="MWKRLLVVSAVSAAMSSMALAAPLTVGFSQVGSESGWRAAETNV
                     AKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKD
                     AEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG
                     ASVAIDRKKGFAEAIKNAPNIKIIRSQSGDFTRSKGKEVMESFIKAENNGKNICMVYA
                     HNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMIDGEANASVELTPNMAGPA
                     FDALEKYKKDGTMPEKLTLTKSTLYLPDTAKEELEKKKNMGY"
     gene            30094..31596
                     /locus_tag="IRB70_001484"
     CDS             30094..31596
                     /locus_tag="IRB70_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBC0631411.1"
                     /translation="MNTNQHQEILRTEGLSKFFPGVKALDNVDFSLRRGEIMALLGEN
                     GAGKSTLIKVLTGVYHADRGTIWLEGQAISPKNTAHAQQLGIGTVYQEVNLLPNMSVA
                     DNLFIGREPKRFGLLRRKEMEKRATELMASYGFSLDVREPLNRFSVAMQQIVAICRAI
                     DLSAKVLILDEPTASLDTQEVELLFGLMRQLRDRGVSLIFVTHFLDQVYQVSDRITVL
                     RNGSFVGCRETRELPQIELVKMMLGRELDTHALQRAGRTLLSDKPVAAFKNYGKKGTI
                     APFDLEVRPGEIVGLAGLLGSGRTETAEVIFGIKPADSGTALIKGKPQTLRSPHQASV
                     LGIGFCPEDRKTDGIIAAASVRENIILALQAQRGWLRPISRKEQQEIAERFIRQLGIR
                     TPSTEQPIEFLSGGNQQKVLLSRWLLTRPQFLILDEPTRGIDVGAHAEIIRLIETLCA
                     DGLALLVISSELEELVGYADRVIIMRDRKQVAEIPLAELSVPAIMNAIAA"
     gene            31610..32632
                     /locus_tag="IRB70_001485"
     CDS             31610..32632
                     /locus_tag="IRB70_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313234.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0631412.1"
                     /translation="MPQSLPDTTPPKRRFRWPTGMPQLAALLLVLLVDSLVAPHFWQV
                     VLQDGRLFGSPIDILNRAAPVALLAIGMTLVIATGGIDLSVGAVMAIAGATTAAMTVA
                     GFSLPIVLLSALGTGILAGLWNGILVAILKIQPFVATLILMVAGRGVAQLITSGQIVT
                     FNSPDLSWFGSGSLLFLPTPVIIAVLTLLLFWLLTRKTALGMFIEAVGINIRAAKNAG
                     VNTRIIVMLTYVLSGLCAAIAGIIVAADIRGADANNAGLWLELDAILAVVIGGGSLMG
                     GRFNLLLSVVGALIIQGMNTGILLSGFPPEMNQVVKAVVVLCVLIVQSQRFISLIKGV
                     RNRDKT"
     gene            32619..33614
                     /gene="yjfF"
                     /locus_tag="IRB70_001486"
     CDS             32619..33614
                     /gene="yjfF"
                     /locus_tag="IRB70_001486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313235.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease YjfF"
                     /protein_id="HBC0631413.1"
                     /translation="MIKRNLPLMITIGVFVLGYLYCLTQFPGFASTRVICNILTDNAF
                     LGIIAVGMTFVILSGGIDLSVGSVIAFTGVFLAKVIGDFGLSPLLAFPLVLVMGCAFG
                     AFMGLLIDALKIPAFIITLAGMFFLRGVSYLISEESIPINHPVYDTLSSLAWKIPGGG
                     RLSAMGLLMLAVVVIGIFLAHRTRFGNQVYAIGGNATSANLMGISTRSTTIRIYMLST
                     GLATLAGIVFSIYTQAGYALAGVGVELDAIASVVIGGTLLSGGVGTVLGTLFGVAIQG
                     LIQTYINFDGTLSSWWTKIAIGILLFIFIALQRGLTVLWENRQSSPVTRVNIVQR"
     gene            complement(33647..34645)
                     /gene="fbp"
                     /locus_tag="IRB70_001487"
     CDS             complement(33647..34645)
                     /gene="fbp"
                     /locus_tag="IRB70_001487"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 fructose-bisphosphatase"
                     /protein_id="HBC0631414.1"
                     /translation="MKTLGEFIVEKQHEFSHATGELTALLSAIKLGAKIIHRDINKAG
                     LVDILGASGAENVQGEVQQKLDLFANEKLKAALKARDIVAGIASEEEDEIVVFEGCEH
                     AKYVVLMDPLDGSSNIDVNVSVGTIFSIYRRVTPVGTPVTEEDFLQPGNKQVAAGYVV
                     YGSSTMLVYTTGCGVHAFTYDPSLGVFCLCQERMRFPEKGKTYSINEGNYIKFPNGVK
                     KYIKFCQEEDKSTNRPYTSRYIGSLVADFHRNLLKGGIYLYPSTASHPDGKLRLLYEC
                     NPMAFLAEQAGGKASDGKERILDIIPETLHQRRSFFVGNDHMVEDVERFIREFPDA"
     gene            34821..36194
                     /gene="mpl"
                     /locus_tag="IRB70_001488"
     CDS             34821..36194
                     /gene="mpl"
                     /locus_tag="IRB70_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-
                     meso-diaminopimelate ligase"
                     /protein_id="HBC0631415.1"
                     /translation="MRIHILGICGTFMGGLAMLARQLGHEVTGSDANVYPPMSTLLEK
                     QGIELIQGYDASQLDPQPDLVIIGNAMTRGNPCVEAVLEKNIPYMSGPQWLHDFVLRD
                     RWVLAVAGTHGKTTTAGMATWILEQCGYKPGFVIGGVPGNFEVSARLGESDFFVIEAD
                     EYDCAFFDKRSKFVHYCPRTLILNNLEFDHADIFDDLKAIQKQFHHLVRIVPGQGRII
                     WPENDINLKQTMAMGCWSEQELVGEQGHWQAKKLTTDASEWEVLLDGEKVGEVKWSLV
                     GEHNMHNGLMAIAAARHVGVAPADAANALGSFINARRRLELRGEANGVTVYDDFAHHP
                     TAILATLAALRGKVGGTARIIAVLEPRSNTMKMGICKDDLAPSLGRADEVFLLQPAHI
                     PWQVAEVAEACVQPAHWSGDVDTLADMVVKTAQPGDHILVMSNGGFGGIHQKLLDGLA
                     KKAEAAQ"
     gene            complement(36350..36901)
                     /locus_tag="IRB70_001489"
     CDS             complement(36350..36901)
                     /locus_tag="IRB70_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein"
                     /protein_id="HBC0631416.1"
                     /translation="MTKQPEDWLDDVPGDDIEDEDDEIIWVSKSEIKRDAEELKRLGA
                     EIVDLGKNALDKIPLDADLRAAIELAQRIKMEGRRRQLQLIGKMLRQRDVEPIRQALD
                     KLKNRHNQQVVLFHKLENLRDRLIDQGDDAIAEVLNLWPDADRQQLRTLIRNAKKEKE
                     GNKPPKSARQIFQYLRELAENEG"
     gene            36995..38347
                     /gene="pmbA"
                     /locus_tag="IRB70_001490"
     CDS             36995..38347
                     /gene="pmbA"
                     /locus_tag="IRB70_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease PmbA"
                     /protein_id="HBC0631417.1"
                     /translation="MALAMKVISQVEAQRKILEEAVSTALELASGKSDGAEVAVSKTT
                     GISVSTRYGEVENVEFNSDGALGITVYHQNRKGSASSTDLSPQAIARTVQAALDIARY
                     TSPDPCAGVADKELLAFDAPDLDLFHPAEVSPDEAIELAARAEQAALQADKRITNTEG
                     GSFNSHYGVKVFGNSHGMLQGYCSTRHSLSSCVIAEENGDMERDYAYTIGRAMSDLQT
                     PEWVGADCARRTLSRLSPRKLSTMKAPVIFANEVATGLFGHLVGAIAGGSVYRKSTFL
                     LDSLGKQILPDWLTVEEHPHLLKGLASTPFDSEGVRTERRDIIKDGILTQWLLTSYSA
                     RKLGLKSTGHAGGIHNWRIAGQGLSFEQMLKEMGTGLVVTELMGQGVSAITGDYSRGA
                     AGFWVENGEIQYPVSEITIAGNLKDMWRNIVTVGNDIETRSNIQCGSVLLPEMKIAGQ
                     "
     gene            38530..38916
                     /gene="cybC"
                     /locus_tag="IRB70_001491"
     CDS             38530..38916
                     /gene="cybC"
                     /locus_tag="IRB70_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313240.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b562"
                     /protein_id="HBC0631418.1"
                     /translation="MRKSLLAILAVSSLVFSSASFAADLEDNMETLNDNLKVIEKADN
                     AAQVKDALTKMRAAALDAQKATPPKLEDKSPDSPEMKDFRHGFDILVGQIDDALKLAN
                     EGKVKEAQAAAEQLKTTRNAYHQKYR"
     gene            complement(38961..39425)
                     /gene="nrdG"
                     /locus_tag="IRB70_001492"
     CDS             complement(38961..39425)
                     /gene="nrdG"
                     /locus_tag="IRB70_001492"
                     /EC_number="1.97.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate
                     reductase-activating protein"
                     /protein_id="HBC0631419.1"
                     /translation="MNYHQYYPVDIVNGPGTRCTLFVSGCVHECPGCYNKSTWRVNSG
                     QPFTKAMEDKIIKDLNDTRIKRQGISLSGGDPLHPQNVPDILKLVKRIRAECPGKDIW
                     VWTGYKLDELNAAQMQVVDLINVLVDGKFVQDLKDPSLIWRGSSNQVVHHLR"
     gene            complement(39583..41721)
                     /gene="nrdD"
                     /locus_tag="IRB70_001493"
     CDS             complement(39583..41721)
                     /gene="nrdD"
                     /locus_tag="IRB70_001493"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBC0631420.1"
                     /translation="MTPHVMKRDGCKVPFKSERIKEAILRAAKAAEVDDADYCATVAA
                     VVSEQMQGRNQVDINEIQTAVENQLMSGPYKQLARAYIEYRHDRDIEREKRGRLNQEI
                     RGLVEQTNASLLNENANKDSKVIPTQRDLLAGIVAKHYARQHLLPRDVVQAHERGDIH
                     YHDLDYSPFFPMFNCMLIDLKGMLTQGFKMGNAEIEPPKSISTATAVTAQIIAQVASH
                     IYGGTTINRIDEVLAPFVTASYNKHRKTAEEWNIPDAEGYANSRTIKECYDAFQSLEY
                     EVNTLHTANGQTPFVTFGFGLGTSWESRLIQESILRNRIAGLGKNRKTAVFPKLVFAI
                     RDGLNHKKGDPNYDIKQLALECASKRMYPDILNYDQVVKVTGSFKTPMGCRSFLGVWE
                     NENGEQIHDGRNNLGVISLNLPRIALEAKGDEATFWKLLDERLVLARKALMTRIARLE
                     GVKARVAPILYMEGACGVRLNADDDVSEIFKNGRASISLGYIGIHETINALFGGEHVY
                     DNEQLRAKGIAIVERLRQAVDQWKEETGYGFSLYSTPSENLCDRFCRLDTAEFGVVPG
                     VTDKGYYTNSFHLDVEKKVNPYDKIDFEAPYPPLANGGFICYGEYPNIQHNLKALEDV
                     WDYSYQHVPYYGTNTPIDECYECGFTGEFECTSKGFTCPKCGNHDASRVSVTRRVCGY
                     LGSPDARPFNAGKQEEVKRRVKHLGNGQIG"
     gene            complement(42115..43770)
                     /gene="treC"
                     /locus_tag="IRB70_001494"
     CDS             complement(42115..43770)
                     /gene="treC"
                     /locus_tag="IRB70_001494"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBC0631421.1"
                     /translation="MTNLPHWWQNGVIYQIYPKSFQDTTGSGTGDLRGVIQRLDYLHK
                     LGVDAIWLTPFYVSPQVDNGYDVANYTAIDPTYGTLDDFDELVTQAKSRGIRIILDMV
                     FNHTSTQHAWFREALNKESPYRQFYIWHDGEPETPPNNWRSKFGGSAWRWHAESEQYY
                     LHLFAPEQADLNWENPAVRAELKKVCEFWADRGVDGLRLDVVNLISKDPRFPEDLDGD
                     GRRFYTDGPRAHEFLHEMNRDVFTPRGLMTVGEMSSTSLEHCQRYAALTGSELSMTFN
                     FHHLKVDYPGGEKWTLAKPDFVALKTLFRHWQQGMHNVAWNALFWCNHDQPRIVSRFG
                     DEGEYRVPAAKMLAMVLHGMQGTPYIYQGEEIGMTNPHFTRITDYRDVESLNMFAELR
                     NNGRDADELLAILASKSRDNSRTPMQWSNGDNAGFTAGEPWIGLGDNYQQINVEAALT
                     DESSVFYTYQKLIALRKQEAVLTWGNYQDLLPNSPVLWCYRREWKGQTLLVIANLSRG
                     IQPWQPGQMRGNWQLVMHNYEEASPQPCAMNLRPFEAVWWLQK"
     gene            complement(43820..45241)
                     /gene="treB"
                     /locus_tag="IRB70_001495"
     CDS             complement(43820..45241)
                     /gene="treB"
                     /locus_tag="IRB70_001495"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS trehalose transporter subunit IIBC"
                     /protein_id="HBC0631422.1"
                     /translation="MMSKINQTDIDRLIELVGGRGNIATVSHCITRLRFVLNQPANAR
                     PKEIEQLPMVKGCFTNAGQFQVVIGTNVGDYYQALIASTGQAQVDKEQVKKAARQNMK
                     WHEQLISHFAEIFFPLLPALISGGLILGFRNVIGDLPMSNGQTLAQMYPSLQTIYDFL
                     WLIGEAIFFYLPVGICWSAVKKMGGTPILGIVLGVTLVSPQLMNAYLLGQQLPEVWDF
                     GMFSIAKVGYQAQVIPALLAGLALGVIETRLKRIVPDYLYLVVVPVCSLILAVFLAHA
                     LIGPFGRMIGDGVAFAVRHLMTGSFAPIGAALFGFLYAPLVITGVHQTTLAIDLQMIQ
                     SMGGTPVWPLIALSNIAQGSAVIGIIISSRKHNEREISVPAAISAWLGVTEPAMYGIN
                     LKYRFPMLCAMIGSGLAGLLCGLNGVMANGIGVGGLPGILSIQPSYWQVFALAMAIAI
                     IIPIVLTSFIYQRKYRLGTLDIV"
     gene            complement(45360..46307)
                     /gene="treR"
                     /locus_tag="IRB70_001496"
     CDS             complement(45360..46307)
                     /gene="treR"
                     /locus_tag="IRB70_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator TreR"
                     /protein_id="HBC0631423.1"
                     /translation="MQNRLTIKDIARLSGVGKSTVSRVLNNESGVSQRTRERVEAVMN
                     QHGFSPSRSARAMRGQSDKVVAIIVTRLDSLSENLAVQTMLPAFYEQGYDPIMMESQF
                     SPQLVAEHLGVLKRRNIDGVVLFGFTGITEEMLAHWQSSLVLLARDAKGFASVCYDDE
                     GAIKILMQRLYDQGHRNISYLGVPHSDVTTGKRRHEAYLAFCKAHKLHPVAALPGLAM
                     KQGYENVAKVITPETTALLCATDTLALGASKYLQEQRIDTLQLASVGNTPLMKFLHPE
                     IVTVDPGYAEAGRQAACQLIAQVTGRSEPQQIIIPATLS"
     gene            46492..46545
                     /gene="mgtL"
                     /locus_tag="IRB70_001497"
     CDS             46492..46545
                     /gene="mgtL"
                     /locus_tag="IRB70_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_003933616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mgtA regulatory leader peptide MgtL"
                     /protein_id="HBC0631424.1"
                     /translation="MEPDPTPLPRRRLKLFR"
     gene            46685..49381
                     /gene="mgtA"
                     /locus_tag="IRB70_001498"
     CDS             46685..49381
                     /gene="mgtA"
                     /locus_tag="IRB70_001498"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBC0631425.1"
                     /translation="MFKEIFTRLIRHLPSRLVHRDPLPGAQQTVNTVVPPSLSAHCLK
                     MAVMPEEELWKTFDTHPEGLNQAEVESAREQHGENKLPAQQPSPWWVHLWVCYRNPFN
                     ILLTILGAISYATEDLFAAGVIALMVAISTLLNFIQEARSTKAADALKAMVSNTATVL
                     RVINDKGENGWLEIPIDQLVPGDIIKLAAGDMIPADLRILQARDLFVAQASLTGESLP
                     VEKAATTRQPEHSNPLECDTLCFMGTTVVSGTAQAMVIATGANTWFGQLAGRVSEQES
                     EPNAFQQGISRVSMLLIRFMLVMAPVVLLINGYTKGDWWEAALFALSVAVGLTPEMLP
                     MIVTSTLARGAVKLSKQKVIVKHLDAIQNFGAMDILCTDKTGTLTQDKIVLENHTDIS
                     GKTSERVLHSAWLNSHYQTGLKNLLDTAVLEGTDEESARSLASRWQKIDEIPFDFERR
                     RMSVVVAENTEHHQLVCKGALQEILNVCSQVRHNGEIVPLDDIMLRKIKRVTDTLNRQ
                     GLRVVAVATKYLPAREGDYQRADESDLILEGYIAFLDPPKETTAPALKALKASGITVK
                     ILTGDSELVAAKVCHEVGLDAGEVVIGSDIETLSDDELANLAQRTTLFARLTPMHKER
                     IVTLLKREGHVVGFMGDGINDAPALRAADIGISVDGAVDIAREAADIILLEKSLMVLE
                     EGVIEGRRTFANMLKYIKMTASSNFGNVFSVLVASAFLPFLPMLPLHLLIQNLLYDVS
                     QVAIPFDNVDDEQIQKPQRWNPADLGRFMIFFGPISSIFDILTFCLMWWVFHANTPET
                     QTLFQSGWFVVGLLSQTLIVHMIRTRRVPFIQSCASWPLMIMTVIVMIVGIALPFSPL
                     ASYLQLQALPLSYFPWLVAILAGYMTLTQLVKGFYSRRYGWQ"
     gene            complement(49587..49973)
                     /gene="ridA"
                     /locus_tag="IRB70_001499"
     CDS             complement(49587..49973)
                     /gene="ridA"
                     /locus_tag="IRB70_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418664.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminobutanoate/2-iminopropanoate deaminase"
                     /protein_id="HBC0631426.1"
                     /translation="MSKTIATENAPAAIGPYVQGVDLGNMIITSGQIPVNPKTGEVPA
                     DVAAQARQSLDNVKAIVEAAGLKVGDIVKTTVFVKDLNDFATVNATYEAFFTEHNAAF
                     PARSCVEVARLPKDVKIEIEAIAVRR"
     gene            complement(50046..50507)
                     /gene="pyrI"
                     /locus_tag="IRB70_001500"
     CDS             complement(50046..50507)
                     /gene="pyrI"
                     /locus_tag="IRB70_001500"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000148566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase regulatory
                     subunit"
                     /protein_id="HBC0631427.1"
                     /translation="MTHDNKLQVEAIKRGTVIDHIPAQIGFKLLSLFKLTETDQRITI
                     GLNLPSGEMGRKDLIKIENTFLSEDQVDQLALYAPQATVNRIDNYEVVGKSRPSLPER
                     IDNVLVCPNSNCISHAEPVSSSFAVRKRANDIALKCKYCEKEFSHNVVLAN"
     gene            complement(50520..51455)
                     /gene="pyrB"
                     /locus_tag="IRB70_001501"
     CDS             complement(50520..51455)
                     /gene="pyrB"
                     /locus_tag="IRB70_001501"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase"
                     /protein_id="HBC0631428.1"
                     /translation="MANPLYQKHIISINDLSRDDLNLVLATAAKLKANPQPELLKHKV
                     IASCFFEASTRTRLSFETSMHRLGASVVGFSDSANTSLGKKGETLADTISVISTYVDA
                     IVMRHPQEGAARLATEFSGNVPVLNAGDGSNQHPTQTLLDLFTIQETQGRLDNLHVAM
                     VGDLKYGRTVHSLTQALAKFDGNRFYFIAPDALAMPQYILDMLDEKGIAWSLHSSIEE
                     VMAEVDILYMTRVQKERLDPSEYANVKAQFVLRASDLHNAKANMKVLHPLPRVDEIAT
                     DVDKTPHAWYFQQAGNGIFARQALLALVLNRDLVL"
     gene            complement(51459..51593)
                     /gene="pyrL"
                     /locus_tag="IRB70_001502"
     CDS             complement(51459..51593)
                     /gene="pyrL"
                     /locus_tag="IRB70_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyr operon leader peptide"
                     /protein_id="HBC0631429.1"
                     /translation="MVQCVRHFVLPRLKKDAGLPFFFPLITHSQPLNRGAFFCPGVRR
                     "
     gene            complement(51874..52269)
                     /locus_tag="IRB70_001503"
     CDS             complement(51874..52269)
                     /locus_tag="IRB70_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBC0631430.1"
                     /translation="MVERTAVFPAGRHSLYAEHRYSAAIRSGDLLFVSGQVGSREDGT
                     PEPDFQQQVRLAFDNLHATLAAAGCTFDDIIDVTSFHTDPEKQFEDIMTVKNEIFSAP
                     PYPTWTAVGVTWLAGFDFEIKVIARIPEL"
     gene            complement(52400..53113)
                     /gene="bdcA"
                     /locus_tag="IRB70_001504"
     CDS             complement(52400..53113)
                     /gene="bdcA"
                     /locus_tag="IRB70_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBC0631431.1"
                     /translation="MGAFTGKTVLILGGSRGIGAAIVRRFVTDGANVRFTYAGSKDAA
                     KRLAQETGATAVFTDSADRDAVIDVVRKSGALDILVVNAGIGVFGEALELNADDIDRL
                     FKINIHAPYHASVEAARQMPEGGRILIIGSVNGDRMPVAGMAAYAASKSALQGMARGL
                     ARDFGPRGITINVVQPGPIDTDANPANGPMRDMLHSFMAIKRHGQPEEVAGMVAWLAG
                     PEASFVTGAMHTIDGAFGA"
     gene            53184..53777
                     /locus_tag="IRB70_001505"
     CDS             53184..53777
                     /locus_tag="IRB70_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709951.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBC0631432.1"
                     /translation="MVTKKQSRVPGRPRRFAPEQAVSAAKVLFHQKGFDAVSVAEVTD
                     YLGINPPSLYAAFGSKAGLFSRVLNEYVGTEAIPLADILRDDRPVGECLVEVLKEAAR
                     RYSQNGGCAGCMVLEGIHSHDPLARDIAVQYYHAAETTIYDYIARRHPQSAQCVTDFM
                     STVMSGLSAKAREGHSIEQLCATAALAGEAIKTLLKE"
     gene            53922..54374
                     /gene="tabA"
                     /locus_tag="IRB70_001506"
     CDS             53922..54374
                     /gene="tabA"
                     /locus_tag="IRB70_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313256.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin-antitoxin biofilm protein TabA"
                     /protein_id="HBC0631433.1"
                     /translation="MIIGNIHNLQPWLPQELRQAIEHIKAHVTAETPKGKHDIEGNRL
                     FYLISEDMTEPYEARRAEYHARYLDIQIVLKGQEGMTFSTQPAGTRDTDWLADKDIAF
                     LPEGVDEKTVILNEGDFVVFYPGEVHKPLCAVGAPAQVRKAVVKMLMA"
     gene            54497..55201
                     /locus_tag="IRB70_001507"
                     /pseudo
     CDS             54497..55201
                     /locus_tag="IRB70_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313257.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
BASE COUNT        13512 a        13951 c        14669 g        13745 t
ORIGIN      
        1 gggagatgac tgacaacgcg ttggtaagcg aggttcgata actcaagatt ctttaaaaac
       61 gccataacat caattatagc gtttttattt aaaataatta gtgggtagct aactgtaatt
      121 gtggttcttc atctttaact ttgataagcg tccacaacgc aatagcacca ataatgtcaa
      181 agaaagccag ggcaataaag aacggcgcga agccgataat gtgaacgaat gccccgatga
      241 acaggttgaa aatcaactga ccgctccacg cacaggctcc tgccataccc actgcggtag
      301 ctacttcgtc ttttttgaac agatcgccac ccagagttgc tgctacagta gaaagacatt
      361 gatgcgagaa cgcgccaata ctaatcagta atacggcaat gtagggattt tcgacaatac
      421 tcaccaggcc aatcgtcatc ataatgacgg ctgcaatagt gaaggtaatt cttcgtgagt
      481 taattaaact cacgccgcga tcgtggaaga acttcgcgac aaaaccactg gctaaacagc
      541 cgagatcgcc cagcaggaaa ggcagccaga cgaacatggc aatttctttc aggctaaaat
      601 gcagcgtttc gacgaagaaa atcggcaccc agaagttaat ggttccccat gccgggtctg
      661 cgagaaaacg cgcgatgcca atcccccaga aattacgttg gctgaggata tgcttgattg
      721 acgttttttc tttcttatct gttttaagat gctgttcttg ccctgattca atatagtggc
      781 gctcttcatc agaaaggcgt ttggcatctt ttggatcttt ataacaaaag aaccaaaata
      841 aagccgcgag caaagcaagg ctacctgaaa caataaacgc aaattgccag ctatgaaaca
      901 taatgcacca ggcaatcaac ggtggagcaa gcatcgcgcc gagtgaggtg cccatattga
      961 aaacacctgt cgccacgcca cgctcttttg ccgggaacca tgttgatgcg gtttttacac
     1021 ccgcaggaat tgccgacgct tcgctgaaac ccatcagggc gcgcataaat gccagacctg
     1081 accatgttcc tgtcaaggca tgccccattg tcgccaggcc ccaaattgcg gcacatatcg
     1141 caaaacttaa cttcagaccc acggtatcaa taaagaagcc cattaccggt tgccctaatg
     1201 tataggccaa ctggaatgca ctgacaatcc atgaatattg ttctttggtt attccggttg
     1261 tctccataat cgttggagcc gcaataccta acgccgttct gtccagataa ttgattacag
     1321 tgataaagca tacgagggca atcatatgcc atcgataatt ctttatttta ttcattttta
     1381 aaccttttaa ttatattaat aaaccctggt tgttggtatt tccatgtaat aggcaataaa
     1441 aatcaggtac agaggaaata ttgaaaatta ttgtgtgtaa atgtctccat ttaaaaagtc
     1501 tggccagttt ttttcaaagt aaataccgtt aatacacggt tgcatacgta aagactttac
     1561 ttcggtaata aaagaacctt gcgaatattg aattgttaat ttgtgatttt tgtcttcagc
     1621 gagttcagag cgaaaacgcc attcttcttt tgcgccgcga cgagtttgtg gtaggcattt
     1681 gccttgtgga tcaataacta tacgcgcccc acggctacca ccacctgcat caatataatg
     1741 tgtcagttga gttaagacgg cggcagaagt cagcgtcata tgccgccaca taaacagctc
     1801 ggcaacttca cccacatgtt tgattgccaa tccatgtcgt tgcacaaatt cgttcaatag
     1861 cagggcatca cgagtggcac gtcggacttt atcggcatgg caaataaatc ccgcatggtc
     1921 agacattcgt gcctgaattt tttctctcac aaccgacaac ggcatcccgg tcccgttatc
     1981 gtgcgcctga gtaatgatct ctcttataga agccagtgcc ggagctgcca gctgtgctat
     2041 atctccatca atattccgct tttgcgtgca accaataaaa cgtgccagac gaacagcaaa
     2101 aacctgcccg gcattcaacg ccgcgccgcc aggtcgggtg acgccgtgtg tgccagcaac
     2161 ttcccccact gcaaaacaac cgggcagaga tgtttgtccc cagatatcga cttcaatgcc
     2221 gccattcata tgctgattat tcatggcaaa ctgcaatggc tgcgtggtga gatcgtaacc
     2281 gtgcatctta tacagcgaga tagacagcgg attcattcgt tgcagtcgtt cgatgggcga
     2341 tggtgccaga gcgtcgttat tttccagata cgcgcgaacg tcgtcgtcca gtcgatctaa
     2401 tgagaagggc aaatcaccag gcaccgctac aggattacga ttgaaatcca taaacacctg
     2461 gcgaccatat tgctgctctt gcgccaccgc catatctaac aagctggagc caaaatccat
     2521 tacccgcgtg gcgtggaacg gccactgata gcctttacgg aagatgtttg aagccagctc
     2581 ctgggtggtg cgatagtaat ctgcgaggaa gttatactcg ttgccctcgg catccacgga
     2641 atagatatat gggatcactt gtacataggt gccggacaaa ttccacggaa acgtgctgcg
     2701 cggcgtgcct ataccaaact ggctttcggt cagattggtg agcgtcagac cttcctccag
     2761 cgccagcccc agcgagccga aacatttgtg tggatacaca ctgtcgcgat aaagctcgcc
     2821 aggccctcct gttgccagta ccacattggg cgcagtcaca attgccagcc cccatgggtt
     2881 atgggcgcga tgaccggtcg cgaggattgc ccccgccaca cggtcttcac cgttttcgtc
     2941 acgctgatgc agcagtttaa tcactgttgc actggtcaac actggaatgg cgagacgctg
     3001 tacttcttcc agcagcactt tcaccattaa ccttgaggta cgcggcccac acgaggttgc
     3061 acgcccggct tcgtcatggt cggtttgata acgaagaatc gcgccatagc gatcttccgg
     3121 taattccaga ccaagatatt gcaacccgcc tagagtgtgc agagaaccta ccgcttcgac
     3181 ataagcggtg tcgtgatcca tcgccccacc gctcgccagt gcctctgcca gtttggtgaa
     3241 gttgtcgccg ttgcccgcgg tagcggcggt aaatagtgtc tgtttatcgg aaccagaaca
     3301 tgccgacgtc cccatatata acccggcggt agcgatcagc acattttgct ggcggcgttt
     3361 aagttccaca gctgcacgca gcccggctgc accactaccg actaccaggg catctgtttg
     3421 ccagagtggg taatcaacac cgtctaccgt gacaacccat gcgggttctg cctgtgcaaa
     3481 accctttggg aaagtgacgt gtgtcagcgc atcaaggatg gtgtcatcaa gctgactcat
     3541 gcatcctcca tcggcgtaaa caggctactt tccatcaggc gtgggtgctt gataattgga
     3601 cggaaagcca tatacggcag aatgtcgcgc tcaatctcca cacccggcgc gatttcaatt
     3661 aattcaacgc cttctgccgt taactggaat actgcgcgtt cagtgatata caacacttcc
     3721 tgaccacttt gctgtgcgta ggcggcgcta aaagtgattt tttccacctg ggtaaccagt
     3781 ttagggattt gacctgactg ggcgatatgc aagccatctg gcgttacatc aatcttgcta
     3841 cctttggcgt cgaacgtgcc gcagaacacc actttacggg cgttttgcgc aatttcgaga
     3901 aaaccgccgg gaccaatgag attgccattg agatgggata cgttgacgtt accgtactga
     3961 tccatctctc ccatgccgag gaaggtgata tcgatccctc cgccactgta gaactcaaat
     4021 tgatcgagtg atggaataat ggcatcggcg ttgcgggcac aaccaaacag agcatcatca
     4081 agcatcatgc cgttatgtac gccttgctcg acgctcagcc ataaactttg gtaaggaacg
     4141 ccttcgcgca gcgctacgcc tggaataccg ccaggaatac caaagccaaa gttggttgaa
     4201 gcgccagcca ccagttcgcg tgctgcccga cgggcaatca ggcggcgtac tggatgacta
     4261 accagttcaa tagcgtcgtt agaactcaga cggcgatgtt gaccgctaat ggtcaggtcg
     4321 taaccgccaa gataggtttg cggttgttcg cggtgttcaa cgatgccatc aaccagaatg
     4381 cccggtaatt tgacccggcg tggttcaatc gcgccagctt ccagcacatc gcgtacctgt
     4441 acgaacactt tgccgccgct gttgtgtgct gccagcgcca tggaatagct atccatatca
     4501 atcgcttctt cttcaaggct gacgttgcca cgcggatcgg cataagtgcc acgcaaaatc
     4561 gcgtaatcca ctttgaaagg gcgataacga agtttggttt caccatcgat ttcaatcagt
     4621 tctaccaggt cgtcggtagt gcattcattc gacttaccgc cgccattgcg tggatcaaca
     4681 aacgatccca gcccaacgtg ggtaaaaagc cccggacgtc cggcgccgat ctcccgtagc
     4741 agtgcctgaa tcacgccacc aggaaagcag taggcttcaa tcgtgttatt ttttaccaga
     4801 gcctgcattt tgggcgacca ggtaaagtgc ccggcaataa tgcgtttgag catctctgcg
     4861 tgcgcaaaac gattagtgcc tttgcagtcg cgatcgccaa tacccagcga gtggattaat
     4921 gtcagatcgc gcgggtgtcc ggtttgcagg aaacgcgctt caatagcagc cagaatatgg
     4981 tcggcttcca ccataccgcc gccgttaccg ctaatagcaa tagtcgcacc gtcctgaatt
     5041 tgcgccgcca gtgcctcggc ggttgttatc ttacgcatac aatttcctta ttgattatgg
     5101 aagctcacgc tacttttttc ggcaaaggcg cgcgtcgcct gctggcaatc ctgagtggcg
     5161 gacattaatc cggccagtag ctggtgcggg taatcggcat gtttattttc cagtgccaga
     5221 atcagttgct taatatgtgc aagcgccacc ggaccacatt tttccagctg cgctaactgg
     5281 ttcgccatcc agctttccac ctgttctttt tctaccactt catcaattaa attcgccgcc
     5341 tgggcttcct gcgccgtcag gcgtttaccc agcatcagca tctggcgacc gaccaccgga
     5401 ccaacctgat taagcacacg ttcaatgccc atccagccag gcaccatgcc gagcatcact
     5461 tccgggttag agaatttcgc gccggggcgg gcaatacgaa tatcgcagca caaggccagt
     5521 tcaataccac cgccgatggt atgaccgttg agattcgcaa cggttaattg gggtaagttt
     5581 cgcaggcgat taaaaacgtc attaccgcgt ttaatccatt ttctgcccat atctaatggc
     5641 gaataggccg accacgattt aatatcgcca cccgcacaaa agaatttatc gccggttgcc
     5701 gttaattcga ctaatcgtaa tgtggtgtcg ttttcaattt catttaaata atggtcgaga
     5761 gattcaatca tctcttcgtt aatagcatga catttatctt cacggttcaa tgtcaggcgg
     5821 caggaagctg ccgctctgct gaacagaacg ggttggtcac tcatgattat tccttagcaa
     5881 taatgcgcga tgcgatcgac gctaatatcc agtgtgctgt caatatcttg ctgccaccaa
     5941 tacggtgaga atatttccag ttcaatagcg ccattaaatc cggcgttttc aaccagccga
     6001 cgaattgacg gaatattgat gacaccatct cccggcattc cacggtcatt gaccagatcg
     6061 gtggtcggca ctaaccagtc ggaaacatga aacgcgagga tgcgttttcc ggcacgcagg
     6121 atctgactgg cgagatccgg atcccaccag acatggtaga catctaccgc cacgccgagg
     6181 ccaaattcgc catcgggatc gagttcatca caccagtcca gcgcctgacg taacgtgcac
     6241 agacaagaac gatcggcagc agtcatcggg tgcagtggct ccagtgcaat tggcacaccg
     6301 acatctttcg aatgtggcag caactggcga atcccttgtt tcacctgttc ccgcgcttcg
     6361 tacagatctt ttgttcccat tggcagaccg ccaaccacct gcatataaca ggcggcgttc
     6421 agtacagcgg cgtcgtccag cgcccggcgg ttatcgtcaa tcgccagttt gcgctccgcc
     6481 agcgtcggtg cggtgtagta ggtgctacgg cacaaaccgg aaacgtttat gttactggca
     6541 gcaagctggc gggcgatttg ctggagatct tcaccctgca actccctgcg ccagggggca
     6601 atggcgccaa taccgcgtgc ggcgcaggca tcaataatgg cgggcagcgg cgttttatag
     6661 cccagtgtcg cggtattgat actgaataaa tccgggcgtt gtaacagatc tctcatgatt
     6721 cagcctcaga agcgcggcat acttaagccg ccgtcgatgg cgaccgcctg accacaggtg
     6781 taaatcagtt taccttccgc catcgcgcgg acagtggaag caatatcagc cggataaccc
     6841 caacgtcccc acggcaccag acctttggca atcagttcgt cgtaataggc cgttgccgga
     6901 atagtcatat cggttttgat gagaccagga cgcacttcat aaacgccaat ttgttcatta
     6961 caaaggcgag cagcaaacag acgagcagcg gcagagacgg cagttttggc aatggtatat
     7021 tcgccgcgat tcatcgccag catgatggcg ttgatggaac tgacgaaaat aatcgagcgg
     7081 tgcggcagtt ctgcttccgg tttcggctgt gccagtaagc gcttactgaa tgcctgagcg
     7141 aggaagaacg gtgcgcgggt gttaatggca atattttggt cgaagctgtc tggttcgagg
     7201 tcgagaagat caccgcgttt tttcactgaa atgcctgcgt tgttgagcag gcagtccaga
     7261 cgtccccact ggttttgcgc tgcgtcgagc atctcttcat gcagggagag atcgcccaca
     7321 tcagcaggga agcaaatcac ttccacgcct tccgccagac attcttgttg tgtggcatgt
     7381 aatttttcta cgctatccgc atccggacga tcattaatca gcagattaaa tccgccacgc
     7441 gcaagctcca gcgcacagcc ctttccaata ccacgagcgg ctccggtaat cacggcaaca
     7501 ggacgagtgg atttcataca atagctctct ttttttgaat tttgtttcct tagtgatgat
     7561 tagcttgcga ctggatgata aaaagatcaa ccatctagtt ggttgatatg cgatggcgat
     7621 cacaggacat ttgataacct gatgaaagta caagtttttg cccttttttc tgaagctgaa
     7681 atcaaatcag gttatgatag tcaccacgaa gaggtcgtgg ggaagcgtta tgtatcttga
     7741 taccagcaac gtacagagcc tgaaagaaaa gctgctgtta tgcgcggtta atgaatttgc
     7801 cgaatatggt tacgaagggg ccagagtcga taatattgtc aaggcagcag ggtgcagtaa
     7861 acagacggtt tatcaccact ttggtaataa agaaaattta tttatcgaag tactggaata
     7921 tacctggaac gatattcgac aaaaagaaaa ggcccttgat ttctcagatc ttccgccaca
     7981 gaaagccatt gagaaaataa tcgattttac atgggattat tatatttcta atccctggtt
     8041 tttaaaaatt gtgcatagtg aaaatcaaag taagggtgtg cattatgcaa agtcacagcg
     8101 tcttttagaa attaaccatg cgcacttgca gttaatggaa tccttattgg atgaagggaa
     8161 gaaacacaat atttttaagc cagatatcga cccattgcag gtgaatatta atattgctgc
     8221 gcttggggga tattatttga tcaaccagca tacgcttggc ctggtttatc acatcagtat
     8281 ggtttcaccc caggcactgg aagccagacg taaggtcatc aaagagacaa tccttagctg
     8341 gcttttggtt gacccttcat ctaccgcgcg cgaataaaac tgccatccgg ctggcgggta
     8401 aacaggacct gttgattatt ccccgtatca atggttaagc ccgtcaccac gccgctggcg
     8461 ttctggcgga ttttcaccat ctgcccgttt tgcaaattac tcagtggctt atccgcgcct
     8521 tctacctgcg ccatggcata gacatcggta gcgggcagtc cgtggtcgcg gaacagctgc
     8581 gccatcgttt taccgggttc gacacgatag gagcgccatt gattatcaat tccgctatct
     8641 ggctggaatg gttgcgtatg ggtggtttgc ggctgctctt ctggctggcc ttcctgtatt
     8701 ggttctggag cgaccggagc cacctgatca ggatcatttt gtggcgtgac taattgcgcc
     8761 cgcagctgtt cttctgtcgg tggttgtgat tgcgactgaa tatctaactg cgcttcacgc
     8821 gtcaccactg gcgcgttggg cgtatcatca gatggaagca gaaatccgac taccaataca
     8881 atggcggcaa taatgatccc ccgacgatgc atcggcggca gcgggtccat gaagcgaaaa
     8941 ttgtccggcg cgtgccagac tttctccagg gttggtttta gttcaaagcg cccgggcatg
     9001 gtttcctcct gctccgcgtc ttgttcctca atcatagcct atgaataagc taacgctatg
     9061 atgtccgtgg taaacccgcc tttattatat tcatacggga tattgctatt gtttcttttt
     9121 ccccgggatt tgtcatcatt cccgcgacaa agttttaccc aaagaagtgt ggctgatatg
     9181 ctgcccgcta ctttataccc taagaaagga aatacgatga ccaccccaac ttttgacacc
     9241 atcgaagcgc aagcaagcta cggcattggt ttgcaggtag ggcaacaact gagtgaatct
     9301 ggcctggaag ggctgctgcc agaagcactg gttgcaggca ttgccgatgc gctggaaggc
     9361 aaacatccgg ctgttccggt tgatgtggtg caccgcgcgc tgcgtgaaat ccacgaacgc
     9421 gccgatgccg ttcgtcgtca gcgtttccag gcgatggctg ctgaaggtgt gaaatacctg
     9481 gaagaaaacg ccaaaaaaga aggtgtaaat agcaccgaat ctggcctgca attccgcgtg
     9541 atcaaccagg gcgaaggcgc aattccggca cgtaccgacc gcgttcgtgt tcattacacc
     9601 ggaaaactga tcgacggcac cgtgtttgac agctccgttg ctcgcggcga gccagctgaa
     9661 ttcccggtta acggcgtgat ccctggctgg attgaagcac tgactctgat gccggtaggt
     9721 tctaaatggg aactgactat cccgcaggaa ctggcatatg gcgagcgcgg cgctggcgcg
     9781 tccatccctc cgttcagcac cctggtgttt gaagtcgaac tgctggaaat cctctaagca
     9841 gcgcattctg ttcccctcga accagagggg agcaggcatt cagcaataaa cccttcagtt
     9901 tgccaaacgg cgctatttta tgttgcaaag accctgtaag cgtgtatttt tgtgagctgt
     9961 ttcgcgttat caccgtgata tgacactcac tttaaacata aaattaacat tagatctaaa
    10021 tcttagtatt catcccgcgt attgttacct aatatcgatg agtcccgata cagattcgtc
    10081 gtatcataga ctgactaaag gccgtagagc ctgaacaaca cagacaggta caggaagaaa
    10141 aaaacatggt agatcaggta aaagtcgttg ccgatgatca ggctccggct gaacagtcgc
    10201 tacggcgcaa tctcacaaac cgacatattc agcttattgc cattggcggt gccattggta
    10261 cagggttgtt tatggggtcc ggcaaaacga ttagccttgc cgggccgtcg atcattttcg
    10321 tttatatgat catcggtttt atgctctttt tcgtgatgcg ggcaatgggg gaattgctgc
    10381 tttcgaatct ggaatacaaa tcttttagtg acttcgcttc cgatctactc gggccgtggg
    10441 caggatattt caccggctgg acttactggt tctgctgggt tgtaaccggt atggcagacg
    10501 tggtggcgat cacggcttat gctcagttct ggttccctgg gctttctgac tgggttgctt
    10561 cgttatccgt gatcattctg ttactggttc taaacctcgc cacggtaaaa atgttcggtg
    10621 agatggagtt ctggtttgcg atgatcaaaa tcgtcgccat cgtgtcgctg attgttgtcg
    10681 gcctggtcat ggtggcgatg cactttcagt caccgaccgg tgtggaagca tcatttgcac
    10741 atttgtggaa tgacggcggc tggttcccga aaggcttaag tggcttcttt gccggattcc
    10801 agatagcggt ttttgctttc gtggggattg agctggtagg tacaacagct gcggaaacca
    10861 aagatccaga gaaatcactg ccacgcgcga ttaactccat tccgatccgt atcattatgt
    10921 tctacgtctt ctcgctgatt gtgattatgt ccgtgacgcc gtggagttcg gtagtcccgg
    10981 agaaaagccc gttcgttgaa ctgtttgtgt tggtaggttt gcctgcggct gccagcgtga
    11041 tcaactttgt ggtgctgacc tctgcggcgt cttccgctaa cagcggtgtc ttctctacca
    11101 gccgtatgct gtttggtctg gcccaggaag gtgtggcacc gaaagcgttc gctaaactct
    11161 ctaagcgcgc cgtacccgcg aaagggctga ccttctcctg catctgcctg ctcggcggcg
    11221 tggtgatgtt gtatgtgaat cccagcgtga ttggcgcgtt cacgatgatt acaaccgttt
    11281 ccgcgattct gtttatgttc gtctggacga ttatcctttg ctcgtacctg gtgtatcgca
    11341 aacagcgtcc gcacctgcat gagaaatcaa tctacaagat gccgctcggc aagctgatgt
    11401 gctgggtatg tatggcgttc tttgtgtttg ttctggtgtt gttgacactg gaagatgaca
    11461 cccgccaggc gctgctggtt accccgctgt ggtttatcgc gctggggctg ggctggttgt
    11521 ttattggtaa gaagcgggct gctgaactgc ggaaataacc gcattatcat gctggatggc
    11581 gcaatgccat ccagctttta gatcactcac ccgccagtgc gcgcgggaat agtacattgt
    11641 tttccaggct gatgtgctcc atcaggtcat caatcagttc attaatgccg ttatacatcg
    11701 ctttccaggt ggtgcaggct tccggcggcg gtgtgacgtt attggtagtg tgtttgatta
    11761 cttccagcag ttcacccgct tcatcgtgct cgctttccat tacgctgatt ggccccattg
    11821 cctggctgcc catgccttgt ttaatcatcg ggaagagaat ttgctcttct ttcatcatgt
    11881 ggctggaaag ctcttcatgc agcatagtca ggtattttgt cagccctttt ggcacacttg
    11941 gtttgtcggc gtgaacgcgc tcgactttag tcgcttgcag gatcagctcc ggcagctgct
    12001 cgcgatggcg atcgtgatag cgcacaataa tgtggtcgat gatttccgcc agcggcgcgc
    12061 tacgccagtc tttctcaatc ggttgttcag caagctttgc cagttcggct tcaatgacgt
    12121 caacatccag ttctttacgt gccgccgcgc gcgccagcgt ctgcttaccg ccacagcagt
    12181 aatccatatc atatttacga aacagagccg aagcgcgagg aatagagagc gccagttcac
    12241 ctaaaggttg gtcgcgataa gccatagctg atacctcatt cttaataaga taagatgcat
    12301 tttaaatgca tctttaaggc aaaagctata acccttacgt agcagaggct tatttaactc
    12361 actgccagcg tgtcaacttt ctgagacaga ttcagttaaa ggtttttctg gttttgctct
    12421 gaccgcgatg accacgccaa tcactaacag cgcgataccg ctcagcgtca ttagcggcgg
    12481 catttgctgg cggagtaaaa aggtgtacag caaacctgcc agcgtttcga aaacaatcag
    12541 cggcccgaga atcactgtcg gtaatcgctg gctggcgacg ttccagcaga gtgcgccaac
    12601 ccatgagcaa agcacggcta tcgcaaccat cagactaata aacaccagcg gacgggggcc
    12661 aaagggtaag gagaagtccg gcgtttgcat attcagccag taacaggcga cgagatagcc
    12721 gatgagagaa accggcagcg tgaccagcgc ctgcgccgtc gcccacatca tcggatgttt
    12781 gtcgggattt tcccgcagcc agcgggcgtt gcgcagggca taccatgccc agcagaccac
    12841 ggaaactaac gctagcacga tgcctgaggt ataacgtgcc cagtcaaaat cggggagtcc
    12901 gtggtttaac tcagcaatat tcacacacgc caggccgatg ccaatacaaa tcagtgccgg
    12961 ggcgagtttt ccccacgcga gtttgccgtc gcgctggcta taaagcagat tggcaaaaac
    13021 gggaatcacc accggcaggg tgccgataat catcgtggaa acaggcgcgc cagtacgttg
    13081 aatggcactg gcaaggcaga agtaatagat aaggttgccc atcatggtga gcatcaaggc
    13141 ggtaagccag tcgcgacgcg ccaactgacg cagacgcacg cgtcccagcc aggcaatggg
    13201 cagcgcaatt aaccctaacg ccagataacg ccccatcgac tgcaacatcg ccgggtattc
    13261 cggtacgatc aacggcccga caaaaataag cccccacatc aaccctgcta acagggcgta
    13321 cagcacgccg ctaatcatta ctggcatcca ttggtctgtc agaagaaagt tcaggaagca
    13381 gacatgattg ctcccggcat cccgtcatta tcagagagga tgcgggagga tgccacttta
    13441 attaactagt tattaacatt aaaaagatgg cttacgcttt cggctaacgt tgtcgttggg
    13501 cggccaatca atttgctaag cgttttgctg tcatcaaaca gaccgccttt cgatgcgcca
    13561 acgtcagaat ccgccagcat atccgccagt ccgtcaggca gtccgacgct tttcagcgcc
    13621 gcggcgaaat cagcttcgct caggttttga taggtaatcg gtttgccgct ctgtttggta
    13681 agttctgccg ctaactgtgt cagcgtccag gcactatcgc ccgccagttc gtaaaccttg
    13741 ccttcgtgac cggcttcgct aatcacgcgt gccgcagcta ccgcataatc agcccgcgtt
    13801 gctgaggcaa ttttgccatc gcccgcggca ccgataaata cgccgtgttc cagtgctgcc
    13861 ggggcgctgg cgaggtagtt ttcgctgtac cagccgttgc gcagcagggt gtaaacgatg
    13921 ccagaatcag ccagcatttt ctccgtctcg atgtgctcat cggcgaggcc gagcggggag
    13981 gtatctgcat gtagcaggct ggtataagcg ataaatttca cgtccgccgc ctttgcggca
    14041 ttaataacat tacgatgctg cgtggcacgt tgacccactt cgctggaaga gatcagcagt
    14101 aatttttcca ctccctgaag tgcagatgtc agtgcggctt catcgccgta atcagcctga
    14161 cgcacggtaa tgccttgtgc tgtcagtgcc tgtgcttttg ccggattacg aacgatagcc
    14221 actatttggc tggcaggaac cgttttcatc aaggattcaa taacatagtg accaagttgg
    14281 ccagtggcac cagtaatagc gatcatggga agtctccatc gttttgtctt gtgtttaaat
    14341 acgctaacac ttaaacttac ttttagtaag tacgcacaaa aaggtaagta tgaaatgagt
    14401 caggttagcc tgtcgcaaca actgaaagag ggtaacctct tcgccgaaca gtgcccgtcg
    14461 cgcgaggtgt tgaaacacgt caccagtcgt tggggggtat tgattctggt cgcgcttcgc
    14521 gaaggtacgc accgttttag cgacctgcgc cgcaagatgg gtggggtgag tgaaaagatg
    14581 cttgcgcagt cgttacaggc attagaacag gatgggtttc ttaaccgtat ctcttatccg
    14641 gtggtgccgc cgcatgtgga atacagcctc acgccgctgg gcgagcaggt gagcgaaaag
    14701 gttgctgcac tggcggactg gattgagttg aatttgcctg aggtgctggc agtgcgggat
    14761 gaacgtgcgg cataacagcc ggatgcgctg cgcttatccg gcctacggtt catgacttgt
    14821 agggcggata agatgcgaca gcatcgcatc tgccaataaa tgccggatgc ggttgatgat
    14881 ttgtaggccg aaaaagaagt gttttactta ctcaaatcca cctgataaat cgcaaagccg
    14941 atatcatcgg tcgcgacttt cttcatcgga tattgtcctt tctctttaat aaacgccgcg
    15001 gctttatctg acggagaggt ttcgaaacgg atatccagtt tcttatcgcc agctatcggt
    15061 gctaaacgcc agttgttatc tgccgccggg tgaatttccc ccgcacgctt cgactcatca
    15121 gcaatccacg ctgccagtac cgagcggttc tcatccggtg aagcaaaagc gatatggctg
    15181 tcgcccgtac cggcaaattt gccaccgtaa gcgcgatagt tattggtggc aacgaggaac
    15241 atggcgttcg gatcaatcgg cttgccatta aaggtcaggt tcttaatcct ttccgcattg
    15301 gcattaacca tctggcactc gccgtcataa cgggcaggct gggtaacatc aatctgataa
    15361 ttcacaccat caatcacatc aaagttatag gtgcggaaac catcccagtt gatgagtgac
    15421 tgtggtttcg tgctgttagg atcaatctgg ttaaactgtc cggcggagca ctccagccac
    15481 tctttcacct ctttaccgct ggctttcacc acaatcagcg tattgggata gagataaaga
    15541 tcggcggcat tacggaaggt caactgacct ttttccacct ccacatagct tgccgggtca
    15601 tttttgcgac caccaacttt aaacggtgcg gcagctgaaa gcactggcag ttttgccaga
    15661 tccggatcgc cctgaatgta atgctcgaca tacgcttttt gcgcgttgtt caccacctgc
    15721 acggtcggat cgtcctgcac cagtgccaga tagctataca tattgtcggc agatttaccg
    15781 attggcttgc tgacgaactg gcgtgtggca tcgtgatcgg ctttgagtgt ttctaccagc
    15841 ttgctgtctt ccgccgcgag ggatttttta ttagcgatgt cgtaaatcgg tcgtgcttcc
    15901 gctttcgcct gtgttacctg ccatttaccg ctgtcattac tgagttgtaa gtcgaccaca
    15961 ccaagatgat cgccccacat gcctggcatt accgccggaa caccattcag cgtgcctttc
    16021 gcgatatcag ctccttcgat atcagcaaaa tctttacctg ggaaaacggc gtgagcatgg
    16081 ccaaacataa tggcgttaac gcccggaatt tcactgaggt aataaactga gttttccgcc
    16141 atcactttat acggatcggc agacagcccg gaatgcgcca gaacgacaac aacatcggca
    16201 cctttctcgc gcatttcagg cacgtatttg cgcacggttt cggtaatatc attcaccgtc
    16261 actttcccgg ataaattagc tttatcccag cccatgattt gcggcggtac gacgccaata
    16321 tagccaatct tcagcgtctg tttttttccg tctttatcga ccacttcggt atctttaatt
    16381 aaatacggtg taaacattgg ctgtttggtt ctggcgtcaa tgacgttggc atttacataa
    16441 gggaatttcg ctcccgccag cgcatttttc aggtaatcca gaccgtagtt aaactcatgg
    16501 ttgccaagcg tgccgacggt atagtccagc gtatttaatg ccttatacac tgggtgaata
    16561 tcacctgctt ttaatccttt cgccgacatg taatctgcca gcggactccc ctgaatcaaa
    16621 tcgccgttat cgaccagtac gctgtttttc acttcattgc gggcatcgtt aatcaggctt
    16681 gccgtacgta ccagtccgaa tttttccgtg gcggtgtctt tgtaataatc gaaatccatc
    16741 atgttgctat gcagatcagt ggtttccatg atacgcagat cgaccgtcgc tgcattcaca
    16801 ctggcggcaa tcagcgtggc caggagcgtt gcgctaaact taatcatcag ggacatcctt
    16861 ttatcatcgg gaatacgaaa gaaaagagag aataaacgtc ttacttatag aacagtgaag
    16921 aatgccacaa ttttacgctt tgaaaatgat gacactatca cagttggcgc attcattaac
    16981 gatagggtat aagtaaaaca ataagttaac accgctcaca gagacgaggt ggagaaatgt
    17041 tagatcaagt atgccagctt gcacggaatg caggcgatgc cattatgcag gtctacgacg
    17101 ggacgaaacc gatggacgtc gtcagcaaag cggacaattc tccggtaacg gcagcggata
    17161 ttgccgctca caccgttatc atggacggtt tacgtacgct gacaccggat attccggtcc
    17221 tttctgaaga agatcctccc ggttgggaag tccgtcagca ctggcagcgt tactggctgg
    17281 tagacccgct ggatggtact aaagagttta ttaaacgtaa tggcgaattt accgttaaca
    17341 ttgcgctcat cgaccacggc aaaccgattt taggtgtggt gtatgcgccg gtaatgaacg
    17401 taatgtacag cgcggcagaa ggcaaagcgt ggaaagaaga gtgcggtgtg cgcaagcaga
    17461 ttcaggtccg cgatgcgcgc ccgccgctgg tggtgatcag ccgttcccat gcagatgcgg
    17521 agctgaaaga gtatctgcaa cagcttggcg aacatcagac cacgtccatc ggctcttcgc
    17581 tgaaattctg cctggtggcg gaaggacagg cgcagctgta cccgcgtttc gggccaacga
    17641 atatttggga taccgccgct ggtcatgctg tggctgcggc tgccggagcg cacgttcacg
    17701 actggcaggg taaaccgctg gattacactc cgcgcgagtc gttcctgaat ccggggttca
    17761 gagtgtctat ttattaatta atttatgcag caggtccatc acttgctgca cctcttcctg
    17821 agtaagcgcc ccgtctttgg cccattgcac gcgaccgtct ttatccagca ccactacagc
    17881 ggaacttttt tcatccagct gccaggcacc gcgtgcgacg ccattgctat caacaataaa
    17941 ctgcgaccag ggataaagct ttttattact ctccagactg ctgcgcacaa acatgccgga
    18001 acccggaatt gcgtcgtcgg tgttaacaat ggtggtggtc tggtaacgat cgtgcggtaa
    18061 cttcgctgat ttaatcgctt caatcagcgt cgcatttttc tcttttgcag aggtgcgacc
    18121 agcaatatgt tgcagtactc gcacttttcc cactaactgc gcgctgttcc aggttttgta
    18181 gctaaactga tctttatcaa gcaccaactc gccacgatcg gtgatgccaa tcggcggcac
    18241 tcgctgaccg gtttcgaact gatgtgcgga agccatcatc ggcaacagca ggcaggtgag
    18301 tgccagaatc ttgcgtaggg tcatggtgtt tccttcttat gatatgcagg tgatccgacc
    18361 acttgggtct gagttttaat catatgtgct atttatcgaa tttcccgcaa gtgtgatgcc
    18421 agtttgcggt caagcgcaca aatcatatga aaaatgaatg cttatactga agaccgcgct
    18481 tcggtaaaaa gataattctg aataattgta acctttaggt aaaaaaagtt atacgcggtg
    18541 gaaacattgc ccggatagtc tatagtcact aggcattaaa atttgcgcct cataatcgtt
    18601 gggccgattg tggcaccgca caggcgtaat actcagcagg agataacaat gaaaattttc
    18661 caacggtaca acccacttca ggtggcgaag tacgtaaaga tcctgttccg tggacggtta
    18721 tacatcaagg acgttggcgc ttttgaattt gataagggta agattcttat cccaaaagtg
    18781 aaggataagc tgcatttgtc agtgatgtcc gaagttaacc gtcaggttat gcgtctgcaa
    18841 acagagatgg cttaaccaaa gtgctatgca gtaataagac ggctcctgat tcgggagccg
    18901 ttgatgtttc tggggttacg cgacgctttc ttctttatct ttagcgtcag gcagttttgg
    18961 cgaaagggcg gtggccttgc tgtcgattcg ggtcaccagc agctggtcga tgcggtagtt
    19021 atcgatatcc accacttcaa atttgtagcc ggcgaatttc accgaatcgg tgcgtttcgg
    19081 gatcttacgc agcataaaca tcataaagcc gccgatggtt tcgtagttgc ccgactgcgg
    19141 gaactcgtca atatccagca cgcgcatgac gtcgtcaatc ggggtgccgc cgtcaatcag
    19201 ccatgagttc tcatcacggg cgacaatctg ctcttccagc ccctgaccga ccagatcgcc
    19261 catcagcgtg gtcatcacgt cgttgagggt gatgatcccc actaccagcg cgtactcgtt
    19321 catgatcacc gcgaagtctt cacctgcggt tttaaaactt tccaacgctt ctgaaagggt
    19381 taacgtatcc ggcacaatca gcgtgttgcg aatttgtacg ccgctgttca gtgccaggct
    19441 ttggttagcc agcacgcggt tcagcaggtc tttagaatcg acatatccga tgatgtggtc
    19501 aatatcttca ttacagacga gaaacttaga gtgcggatgt tccgccacct tattcttcag
    19561 actttgctca tcttcgtgga gatcaaacca aatcacgttt tcacgcggtg tcattgaaga
    19621 cggaacggta cgggattcca gctcaaagac gttttcaatc agctcgtgtt cctgtttacg
    19681 taacacgccc gccagcgcac cggcttccac taccgcgtag atgtcatcag aagtgatgtc
    19741 atctttacgt accattggca gtttgaaaat acggaagatt atgttcgcca gtccgttgaa
    19801 gaaccacacc agcggggtgc aaacgtacag gcagaagcgc atcgggttga tgatacgcaa
    19861 agccacagct tctggcgcaa tcataccgat gcgtttcggg gttaaatccg caaacaggat
    19921 aaacatgcca gtcactaacg agaaagagag aataaagctc agttgctcag agagttctgc
    19981 cgacatatag cgggagaaca ggctgtgaaa agctggagaa aatgccgcat caccgacgat
    20041 accgccgaga atcgccactg cgttcagacc gatttggacc acggtaaaga acatgccggg
    20101 attttcctgc atattcagaa cgcgttgggc atttatattg ccttcatcag ccagcagttt
    20161 aagtttgatt ttgcgtgagg cggcaagcga gatctcggac atcgagaaga acgcacttac
    20221 agcgatcaaa cagagtatga ctaaaatact gtttaacata tcttatccga cctttcaggc
    20281 cagatcctcg gaaggggaag ttgattaatt tgtgtgaaat acacattgaa agccgattcg
    20341 aagaaagtga accggcattt tcagtggcta gtatagcgta aggtactgta aagccgccag
    20401 agggttaaaa ttcagacagc tgaaaaatga aaaactgcct gatgcgctat accgaacagg
    20461 cctacgcagt ccccgcaata tattgaattt ggacgatttt gtaggcctgg caaggcgttt
    20521 acgccgtatc cgacataaac aaaatgcact ttatcaacaa tctacatttg tacccgtaac
    20581 gctatgcttc cggcggcaga cagacgccaa ttccgccaat tccacagtaa ccatacgggt
    20641 ttttatgcag atattgctgg tggtcatctt cggcataata aaacggtgtg gcgttagcga
    20701 tttccgtggt gatgcgacga tcgtcatcgg cggcaagcat cgccgcctga aaacgttcca
    20761 gactggcgcg agcggcggca tcctgttctg gggtcagagg ataaatcgct gaacgatact
    20821 gcgtaccgtg gtcattgccc tgacgcattc cctgggcggg atcgtgattc tcccaaaata
    20881 cttgtagcaa ctgctcatag ctgatgacgg atggatcgta aacaatgcgc accgcttcgg
    20941 catggccagt atcgccggag cacacttccc gataagtcgg atttggcgta tagccgccgg
    21001 tatagcctgc ggcggtgctg taaacgccgg gtaactgcca gaacagacgc tccacacccc
    21061 agaaacaacc catcgcaaaa atggcaatct ccattccgtc aggtacattg gtcattgagt
    21121 gaccgttgac cgcatgcagc gtggctacgg gcatcggggt gttacgtcca ggcagggcat
    21181 cggcggggga aaccagatgc tttttatcaa ataaactcat ggtgtcgctc tcccgaaaat
    21241 cggtcattgg ggttaaggtt gtaacaagag gcgtatttgc acacaataac cgctgtgaat
    21301 aggtctaaag taaaacataa gaaatatttg gggtttagtc tgctttttaa tccatattac
    21361 tggatttttg ttaagccgtt taacggcgtt ccaggggcag gaaaaaagga tattcaggag
    21421 aaaatgtgcg ctatatccga cagttatgct gtgtaagctt actctgctta agcggatctg
    21481 ccgtcgccgc gaacgtccgt ctacaggtcg aggggttatc gggacagctg gaaaagaacg
    21541 ttcgtgcgca gctttctacg attgaaagtg atgaagtgac gccagaccgt cgctttcgcg
    21601 cacgcgtcga tgatgccatc cgcgaaggtc tgaaagcgct gggttattac cagccgacca
    21661 ttgaatttga tctccgtcca ccgccaaaga aagggcggca ggtattgatc gccaaagtca
    21721 cgccaggcgt gccggtgtta attggcggca ccgatgtggt attgcgcggc ggcgcgcgga
    21781 ccgataaaga ctatttgaaa ttgctcgata ctcgcccggc tattggtacg gtactgaacc
    21841 agggcgatta tgaaaatttc aaaaagtcct taaccagcat tgcgttgcgt aaaggttatt
    21901 tcgatagcga atttaccaaa gcgcagctgg gcattgcgct cggcctgcat aaagccttct
    21961 gggatattga ttataacagt ggcgaacgtt accgctttgg gcatgtgacc tttgaaggat
    22021 cacaaatccg cgatgaatac ctgcaaaatc tggtgccgtt taaagagggc gatgagtacg
    22081 aatcgaaaga tctggcagag ctgaaccgtc gactttctgc taccggctgg tttaactcgg
    22141 tcgtagtggc tccacaattt gataaatcgc gcgaaacgaa agtattacca ttgacgggcg
    22201 tggtttcgcc gcgaactgaa aacaccatcg aaaccggggt cggttactct acggacgtgg
    22261 gaccgcgcgt gaaagcgacg tggaaaaagc cgtggatgaa ctcttatggt cacagtctga
    22321 ccaccagtac cagtatttcc gcgccggaac agatcctcga cttcagctat aaaatgccgc
    22381 tgttgaagaa tccactggaa caatattatc tggtgcaggg cggttttaag cgcactgacc
    22441 tgaacgatac cgagtctgac tccactacgc tggtggcttc tcgctactgg gatctctcca
    22501 gcggctggca gcgtgccatt aacctgcgct ggagtctcga ccactttacc cagggtgaaa
    22561 ttaccaacac cacgatgctg ttttatcctg gggtgatgat tagccgcacg cgttctcgcg
    22621 gtggcctgat gccaacctgg ggcgactcgc aacgctactc tatcgactac tccaacacgg
    22681 cctggggctc agatgtcgat ttctccgttt tccaggcgca gaacgtctgg atccgcacac
    22741 tgtacgatcg ccatcgtttt gtgacacgcg gcacgctggg ctggattgaa acgggtgatt
    22801 tcgacaaagt accgccggat ctgcgtttct tcgccggggg cgatcgcagt attcgcggct
    22861 acaaatacaa atcaatcgct ccgaaatacg ccaacggtga cctgaaaggg gcctcgaagt
    22921 tgataaccgg atcgctggag taccagtaca acgtgaccgg aaaatggtgg ggcgcggtgt
    22981 ttgtcgatag cggcgaagcg gtaagcgata ttcgccgcag cgactttaaa accggtaccg
    23041 gggtcggcgt gcgctgggaa tcgccggtcg ggccaatcaa actcgatttt gccgtaccgg
    23101 tcgcggataa agacgaacac gggttacagt tttacatcgg tctggggcca gaattatgag
    23161 tttatggaaa aaaatcagcc tcggcgtggt tatcgttatc ttactgttgc tgggatcggt
    23221 ggcgtttctg gtgggcacca ccagcggcct gcatctggta tttaaagcgg cggatcgctg
    23281 ggtgccagga ctggatattg gcaaggtcac cggcggctgg cgtgatctca ccttgtctga
    23341 cgttcgttat gagcagccag gcgtagcggt aaaagcgggc aatctgcatc tggcggtcgg
    23401 gcttgagtgc ctgtggaaca gtagcgtttg tattaatgac ctggcgctga aagacattca
    23461 ggtcaacatc gacagtaaaa aaatgcctcc ttctgaacag gttgaagaag aggaagatag
    23521 cggcccgctg gatctctcca cgccgtatcc catcaccctg acacgggtgg cgctggacaa
    23581 cgtcaacatc aagattgatg acaccacggt gtcggtgatg gacttcacct ccggcctgaa
    23641 ctggcaggag aaaaccctga ccctgaaacc gacgtcgctg aaaggcctgt tgattgcttt
    23701 gccgaaagtg gcggaagtgg cgcaggaaga agttgtcgaa ccgaaaattg aaaatccgca
    23761 gccggatgaa aaaccgctcg gcgaaacgct gaaagatctc ttttctcgcc cggtattgcc
    23821 ggaaatgacc gacgtgcatt tgccgcttaa cctgaacatt gaagagttta agggcgagca
    23881 gctgcgcgtg acgggtgaca cggacatcac cgtgagcacc atgctgctga aagtgagcag
    23941 catcgacggt aatactaaac tggacgccct ggatatcgac tccagtcaag ggatcgtcaa
    24001 cgccagcggc acggcgcagc tgtcagacaa ctggccggtg gatattaccc tcaacagcac
    24061 actgaacgtg gagccgttga aaggtgaaaa agtgaagctg aaagtgggcg gcgcgctgcg
    24121 cgaacagctg gagataggcg ttaacctttc tggtccggtg gatatggatt tacgcgccca
    24181 gacgcgactg gcggaagccg gattgccgct caacgtggaa gtgaacagca aacagcttta
    24241 ctggccgttc actggagaga agcagtatca ggcggatgat ctgaaactga aacttaccgg
    24301 taaaatgacc gattacacgc tctctatgcg tacggcagtg aagggacagg agatcccgcc
    24361 agccaccatt acccttgatg ccaaaggtaa tgaacagcag gtcaatctcg acaaactcac
    24421 cgtcgcggcg ctggaaggga aaactgaact caaagcgttg ctcgactggc agcaggcaat
    24481 tagctggcgc ggtgagctaa cgcttaacgg cattaacacc gccaaagagt tcccggagtg
    24541 gccgtcgaaa ctcaatggct tgattaaaac ccgcggtagc ctgtacggcg gcacctggca
    24601 gatggaagtg ccagaactga agctgaccgg taacgtcaaa cagaacaaag tgaacgttga
    24661 cggcacgctg aaaggcaaca gttatatgca gtggatgatc ccagggctgc atctggaact
    24721 ggggccaaac agtgccgaag tgaaaggcga gctgggggta aaagatctca atcttgatgc
    24781 caccatcaac gcgccggggc tggataacgc gctgccgggg cttggcggta cagcgaaagg
    24841 gctggtgaaa gtacgcggca cggtggaagc gccacaacta ctggcagata tcaccgcgcg
    24901 cggcctgcgc tggcaggaac tttccgtggc gcaggttcgc gtggaaggcg atatcaaatc
    24961 caccgatcag attgcgggta aacttgacgt acgcgttgag caaatctcgc agcccgatgt
    25021 gagtatcaac ctcgtcaccc tgaatgccaa aggcagcgaa caacagcacg agttacagtt
    25081 gcggattcag ggcgagccgg tttccgggca gcttaatctg gcaggaagtt ttgatcgcaa
    25141 agaagaacgc tggaagggaa ctcttagcaa tacccgcttc cagacgccgg tcggcccgtg
    25201 gtcgctgacc cgcgatattg cgctggatta ccgcaataag gagcaaaaaa tcagcatcgg
    25261 gccacactgt tggcttaacc cgaatgcgga attgtgcgtg ccgcaaacta tcgatgcggg
    25321 ggccgaaggg cgtgcggtgg tgaatctcaa ccgcttcgac ctcgccatgc tgaaaccgtt
    25381 tatgccagaa accactcagg ccagcggtat cttcacgggt aaagcggacg ttgcctggga
    25441 caccacgaaa gaggggctgc cgcagggcag tatcaccctt tcggggcgta acgtgcaggt
    25501 aacgcaaacc gtcaacgatg cggcgctgcc cgtggcgttt cagacgctga atctgacggc
    25561 ggaattgcgt aacaaccgtg ccgaattggg ctggaccatc cgcctgacca ataacggcca
    25621 gtttgatgga caggtgcagg tggccgatcc gcaaggccgc cgtaatcttg gtggcaacgt
    25681 caatatccgt aacttcaacc ttgcgatgat aaaccctatc tttacccgtg gggaaaaagc
    25741 tgcggggatg gtgagtgcca acttacgtct ggggggtgat gtgcaaagcc cgcagttgtt
    25801 tgggctgcta caggttacgg gtgtggatat cgacggcaac tttatgccgt ttgatatgca
    25861 gccgagccag cttgcggtca actttaacgg tatgcgctcg acgcttgccg gtacagtacg
    25921 gacccagcag ggtgagatct acctgaacgg cgacgccgac tggagccaga ttgaaaactg
    25981 gcgggcgcgg gtaacagcga agggcagtaa agtgcgtatc accgtgccgc cgatggtacg
    26041 aatggatgta tcaccagatg ttgtattcga ggctacacca aacctgttta ccctcgatgg
    26101 tcgcgtggat gtcccgtggg cgcgcatcgt ggtgcatgag ctgccggaaa gcgcggtggg
    26161 cgtctccagc gatgtggtga tgcttaacga taacctgcaa ccggaagagg caaaaacggc
    26221 gtcgattccg attaacagca acctgattgt tcacgtcggc aacaatgtgc gcattgacgc
    26281 ctttggcctg aaagcgcggc tgacgggcga tcttaacgtc gttcaggaca aacaagggct
    26341 gggcctgaac gggcagatca acatccctga agggcgcttc catgcctatg gtcaggatct
    26401 gattgtgcgt aagggtgagc tactgttctc tggcccgccg gatcaaccgt atcttaatat
    26461 tgaagctatt cgtaacccgg atgctacaga agacgacgtc atcgccggag ttcgcgtcac
    26521 tggtctggcg gacgaaccga aagcggagat cttctctgac ccggcgatgt cgcaacaggc
    26581 tgccttgtct tatttgctac gtggacaagg gttggagagc gatcagagcg acagtgcggc
    26641 gatgacctca atgctgattg gtctgggggt tgcacaaagt ggtcagattg tgggtaaaat
    26701 cggcgagacg tttggcgtaa gcaatttagc gctcgacacc cagggtgtag gcgactcctc
    26761 ccaggtggtg gtcagcggct atgtattgcc aggtctgcaa gtgaaatacg gcgtgggtat
    26821 atttgactct atagcaacac tcacgttacg ttatcgcctg atgcctaagc tatatctgga
    26881 agccgtgtct ggtgtagacc aggcactgga tttgctctat cagttcgagt tttagcaatg
    26941 cgaatatttg tctacggcag tttacgccac aaacaaggca acagtcactg gatgaccaat
    27001 gcccagttac tgggcgattt cagtatcgat aactaccagt tgtatagcct gggccactat
    27061 ccaggcgcag ttccggggaa cggaacagta cacggtgaag tttatcgtat tgacaacgcc
    27121 acgctggccg aacttgatgc cttgcgcacc aggggcggtg aatacgcgcg ccagttgatt
    27181 cagacgccgt acgggagtgc atggatgtac gtttatcaac gacccgtcga tggattaaag
    27241 ctaattgaaa gcggcgactg gttagacagg gataagtaac catacgcata cgccaccttc
    27301 gggtggcgtt gttttttgcg agacgactcg tattctgttt tgtaattccc tcaccttttg
    27361 cttttctctc cgagccgctt tccatatctg ttaacgcata aaaaactctg ctggcgttca
    27421 caaatgcgca ggggtaaaac gtttcctgta gcaccgtgag ttatactttg tataacttaa
    27481 ggaggtgcag atgcgtatta ccataaaaag atgggggaac agttcaggta tggtcattcc
    27541 taatgttgtg atgaaagaac ttaacttacg gccggggcag agcgtggagg cgcaagtgag
    27601 caacaatcaa ctgattctga cacccatctc caggcgctac tcgcttgatg aactgctggc
    27661 acagtgtgac atgaacgcca cggaacttag cgagcaggat gtctggggta aatccacccc
    27721 tgcgggtgac gaaatatggt aaagaaaagt gaatttgaac ggggagacat tgtgctggtt
    27781 ggctttgatc cagcaagcgg ccatgaacag caaggtgctg gtcgacctgc gcttgtgctc
    27841 tccgttcaag cctttaatca actgggaatg acgctggtgg cccccattac gcagggcgga
    27901 aattttgccc gttatgccgg atttagcgtt cctttacatt gcgaagaagg cgatgtgcac
    27961 ggcgtggtgc tggtgaatca ggtgcggatg atggatctac gcgcccggct ggcaaagcgt
    28021 attggtctgg ctgcgggtga ggtggtggaa gaggcgttat tacgtttgca ggcggtggtg
    28081 gaataaggtg tgtttattta tcgcgggcat aaaaaacccc tactaaccga agcccggcgt
    28141 tcagggttat tacgctagaa gaacttattt attctttgcg cgctcgaagg aggcaacgat
    28201 ttcagcttta gcggcttctg cgttttccca gccttcaact ttcacccact tgcctttttc
    28261 gaggtctttg tagtgctcga agaagtgagc gatctgtgct ttcagcagtt caggcagatc
    28321 gttaacgtct ttaatgtgat cgtattcttt gctcagcttg ctgtgcggaa ccgcaaccag
    28381 tttcgcatct tcaccggctt cgtcggtcat tttcagaacg ccaacaggac ggcaacggat
    28441 cacagaaccc ggctgcagcg ggtacggagt cgggaccagt acgtcaaccg ggtcaccgtc
    28501 cagagacagg gtgtggttga tgtaaccgta gttgcacgga tagaacatcg cggtggacat
    28561 gaagcggtca acgaacagtg cgccgctctc tttgtcgatt tcgtatttga tcggatctgc
    28621 gttagccggg atctcaataa caacgtagat gtcttccggc agatctttac ccgcaggaac
    28681 gttgagtaag ctcatgtctg tttcctttaa aaatatgtgg caaacaagtg ccgagtatta
    28741 tagccaactc gcgccgaatg tcttcgcttg ttttcttctt cattttcctt tttagccagt
    28801 tttaagatgg tttaaagagc aggaaaatcc ataaccgtag ccgcattttt catagtgaga
    28861 tgaaagcgat tacaaacttg tgattaacgt tttatttact tttttgaagt gtgatgtaac
    28921 gcaatccgtt acataacgaa ttgtctatag ttttttcgcg aacatctttt caccaataat
    28981 aattaccccg acgaggacaa ccctatgtgg aaacgcttac ttgtagtctc tgcagtctcg
    29041 gcagccatgt cgtctatggc gttggccgct ccattaaccg ttggattttc gcaggtcgga
    29101 tcggaatccg gctggcgcgc cgcagaaacc aatgtggcga aaagtgaagc cgaaaagcgc
    29161 ggaattacgt tgaaaattgc cgatggtcag caaaagcagg aaaaccagat taaagcggta
    29221 cgttccttcg tcgcgcaagg ggtggatgcg atctttatcg ctccagtggt agcgaccggt
    29281 tgggagccgg tattaaaaga ggcgaaagat gccgaaatcc cggtcttttt gcttgaccgt
    29341 tccatcgatg tgaaagacaa atctctctat atgaccactg tcaccgccga caacatcctc
    29401 gaaggcaagt tgattggtga ctggctggta aaagaagtga atggcaaacc atgcaacgtg
    29461 gtggagctgc agggcaccgt tggggccagc gtcgccattg accgtaagaa aggctttgcc
    29521 gaagccatta agaatgcgcc aaatatcaaa attatccgct cgcagtcagg tgacttcacc
    29581 cgcagcaaag gcaaagaagt gatggagagc tttatcaaag cggaaaacaa cggcaaaaac
    29641 atctgcatgg tttacgccca taacgatgac atggtgattg gcgcgattca ggcaattaaa
    29701 gaagcgggcc tgaaaccggg caaagatatc ctgacaggct ctatcgacgg cgtgccggac
    29761 atctacaaag cgatgattga tggcgaagcg aacgccagcg ttgaactgac gccgaacatg
    29821 gcaggccccg cttttgatgc gctggagaaa tacaaaaaag acggcaccat gcctgaaaag
    29881 ctgaccctga ccaaatccac cctttatctg cctgataccg caaaagaaga gttagagaag
    29941 aagaaaaata tggggtattg aggggcatca atgcctaatg ccgatttgtg ggccgccgga
    30001 taaggcattc acgccgcatc cggcggttgt gcgagatgcc tgatgcgacg ctgttgtgtc
    30061 ttatctggcg cacgctttac aacgggggaa actatgaata ctaaccaaca ccaggaaatc
    30121 ctccgcaccg aaggattaag taaatttttc cccggtgtca aagcgttaga caacgttgat
    30181 ttcagcctgc gccgtggcga aatcatggcg ctgctcggtg aaaacggggc gggaaaatcg
    30241 acgctaatca aagtattaac cggtgtatac cacgccgatc gcggcactat ctggctggaa
    30301 ggccaggcta tctcaccgaa aaacaccgcc cacgcacaac aactcggcat cggcaccgtc
    30361 tatcaggaag tcaacctgct acccaatatg tcggtcgctg ataatctatt tataggccgc
    30421 gaacccaaac gttttggcct tctacgccgt aaagagatgg aaaagcgcgc caccgaactg
    30481 atggcatctt acggtttctc cctcgacgtg cgcgaaccgc tcaaccgctt ttcagtcgcg
    30541 atgcagcaaa tcgtcgccat ttgccgggcc atcgatctct ccgccaaagt gctgatcctc
    30601 gatgaaccca ccgccagcct cgacactcag gaagtagagt tactgtttgg cctgatgcgt
    30661 cagttgcgcg atcgcggcgt cagcctgatc tttgtcactc actttctcga tcaggtctat
    30721 caggtcagcg atcggatcac cgtcttacgc aacggcagtt tcgtaggctg tcgggaaacc
    30781 cgcgagctac cgcagatcga actggtaaaa atgatgctgg ggcgcgagct ggacacccac
    30841 gcgctacagc gtgccgggcg aacattgttg agcgacaaac ccgttgccgc gttcaaaaat
    30901 tacggcaaaa aaggaacgat cgcaccgttt gatctcgaag tacgccccgg cgagatcgtt
    30961 ggcctggcag gcttgctggg atcaggacgt accgaaaccg ccgaagtgat cttcgggatc
    31021 aaacctgctg acagcggcac ggcgttgatc aaaggcaaac cgcaaaccct gcgatcgcca
    31081 catcaggctt cggtactggg cattggcttc tgcccggaag acaggaaaac cgatggcatc
    31141 atcgctgccg cctcggtgcg ggaaaatatc atcctcgctc tccaggccca gcgcggctgg
    31201 ctacgaccca tttcccgtaa agaacagcaa gagattgccg aacgctttat ccgccagctt
    31261 ggcattcgca caccttcaac tgaacaaccg attgaatttc tctctggcgg caatcagcaa
    31321 aaagtgttgc tttcacgttg gctactgact cgtccgcaat ttttgatcct cgacgagcca
    31381 acccgcggca ttgatgttgg tgcgcacgcc gagatcatcc gcctgattga aacgctgtgc
    31441 gccgatggac tggcgctgct ggtgatctcc tccgaactgg aagaactggt gggctatgcc
    31501 gatcgggtga ttatcatgcg cgatcgcaaa caggtggcgg agatcccgct ggcagagctt
    31561 tccgttccgg cgatcatgaa cgccattgcg gcgtaaggag aacagtgtga tgcctcaatc
    31621 tctcccggac actacgccgc cgaaaaggcg ttttcgctgg ccaacaggaa tgccgcagct
    31681 ggcggcactg ttgctggtgc tgctggtcga tagcctggtg gccccgcatt tctggcaggt
    31741 ggtgcttcag gatgggcgtt tgttcggtag ccctatcgac attcttaatc gcgccgcccc
    31801 cgttgcgctg ttggcgattg gtatgacgct ggtgatcgcc actggtggga ttgatctctc
    31861 cgtgggggcg gtgatggcta tcgccggagc cacaacggct gcgatgacgg tcgcgggatt
    31921 cagcctgccg attgttttgt taagcgccct gggcactggc atcctggcgg gattgtggaa
    31981 cggcatactg gtagcgatcc tcaaaattca gccgtttgtc gccaccctga tcctgatggt
    32041 cgccgggcgc ggcgtggcgc aactgatcac ctccggacag atcgtcacat ttaactcacc
    32101 ggatctctcc tggtttggca gcggatcgct gttgttcctg ccaacaccag tcattattgc
    32161 ggtactgacg cttctcctct tctggctgtt gacccgcaaa acggcgctgg ggatgtttat
    32221 cgaagccgtt ggtatcaaca ttcgggcggc aaaaaatgcc ggagttaaca cgcgaatcat
    32281 cgtcatgctc acctacgtgt tgagcgggct gtgtgcggcg attgcgggca ttatcgtggc
    32341 ggcggatatt cgcggtgccg atgccaacaa cgccggatta tggctggagc tggacgccat
    32401 tcttgcagtg gttattggcg gtggatcgct gatgggcggg cgctttaacc tgctgctttc
    32461 ggtggtgggg gcgctgatta ttcagggaat gaacaccgga attttgcttt ctggctttcc
    32521 gccggagatg aaccaggtcg taaaagcggt ggtggtgctt tgcgtgctga ttgttcagtc
    32581 gcaacgcttt atcagtctga ttaaaggggt acgtaaccgt gataaaacgt aatttgccac
    32641 tgatgatcac catcggcgtc tttgtgctgg gttatctcta ctgtctgacg cagtttcccg
    32701 gttttgcttc cacaagagtg atctgcaata tcctgaccga taacgctttt ctggggatca
    32761 tcgccgttgg catgaccttt gtgatcctct ccggtgggat cgatctctcc gtcggttcgg
    32821 tgatcgcctt taccggcgtg tttctggcaa aagtgattgg cgatttcggc ctctcgccgc
    32881 tgctggcgtt tccgctggtg ttggtgatgg gctgtgcctt cggcgcattt atggggcttc
    32941 tgatcgacgc gctgaagatc ccggcgttta tcattaccct tgcggggatg ttctttttgc
    33001 gcggtgtcag ctatctcatc tcagaagagt cgatcccgat aaatcatcct gtttatgaca
    33061 cgctctcaag ccttgcatgg aaaatccctg gcggcggtcg cttaagtgcg atggggctgc
    33121 tgatgctggc ggtggtggtt atcggcatat tcctcgcgca tcgtacccgt tttggtaatc
    33181 aggtatacgc cattggcggc aacgcaacgt cggcaaacct gatggggatt tccactcgca
    33241 gcaccactat tcgcatttat atgctctcca ccggactggc aacgctggcg gggattgtct
    33301 tctcgattta tacccaggcc ggatatgcgc tggcgggcgt aggtgtggaa ctggatgcta
    33361 tcgcctcagt ggtaattggc ggtacgcttt tgagcggtgg cgttggaacg gtattaggga
    33421 cgctttttgg cgtggcgatt cagggactga ttcagactta cataaacttt gatggcacgc
    33481 tgagctcatg gtggacgaaa atcgccatcg gtattttgtt gtttattttt atagcattac
    33541 agcgtggatt aacggtgctg tgggagaatc gtcagagttc gcctgtgaca agagtcaaca
    33601 ttgtgcagcg ataaaaacgc ctctccgtgt ggagaggcgc aggagattac gcgtccggga
    33661 actcacggat aaagcgttcg acatcttcaa ccatatggtc gttgccgaca aagaacgaac
    33721 ggcgctggtg cagggtttcc gggatgatat ccagaatacg ctctttgcca tcgctcgctt
    33781 taccgcctgc ttgttccgcc aggaatgcca tcgggttgca ctcatacagt aaacgcagtt
    33841 taccgtccgg gtggctggcg gtgcttgggt agagataaat accgcctttc agcaggttac
    33901 ggtggaaatc cgcgaccagt gaaccgatat aacgtgaggt atacgggcga ttggtagact
    33961 tatcttcttc ctggcagaat ttaatgtact tcttcacccc gttcggaaac ttaatgtagt
    34021 ttccttcgtt gatggagtag gttttgcctt tctccgggaa gcgcatccgt tcctggcaca
    34081 ggcagaaaac gcccagcgaa ggatcgtaag taaaggcgtg aacaccgcat ccggtggtgt
    34141 aaaccagcat ggtagaggag ccgtatacca cgtaacctgc cgcaacctgt ttgttaccag
    34201 gctggaggaa atcttcttcc gttaccggcg tgccaacagg tgtaacgcgg cggtagatgg
    34261 agaaaatggt accgacagag acgttaacat cgatgttgga cgagccatcc agggggtcca
    34321 tcagcaccac gtattttgcg tgttcacagc cttcaaagac gacaatctca tcttcttctt
    34381 cagaggcaat gcccgcaacg atatcgcgtg ctttcagtgc ggctttcagt ttttcattag
    34441 cgaacaggtc gagtttctgc tgaacctcgc cctgcacgtt ctcagcaccg ctggcaccca
    34501 ggatatcaac cagtcctgct ttgttgatat cgcgatggat aatcttggcg cccagtttta
    34561 ttgccgacag caaagcagtg agctcaccgg tagcatgaga aaactcgtgc tgcttttcga
    34621 caataaattc acctaacgtt ttcataaaac tttccctgca atgtttatgg agtaaagcga
    34681 ccgcaacaat cttaacaaat aatctcaatg ttgcgctcag gtgaatcgcg ccagcaaatt
    34741 gcggattatc ctgaaatgcg tttctcactt gcccgacata tgcgtaaaat gagcggcaga
    34801 ttaaaaaagg atagtgacgt atgcgcattc atattttagg aatttgtggc acgtttatgg
    34861 gcggtctggc gatgctggcg cgccagttag gccatgaagt aacgggttcg gacgccaatg
    34921 tgtatccgcc gatgagcacc ttacttgaga agcaaggcat tgaactgatt cagggttacg
    34981 atgccagcca gctcgatccg cagccggatc tggtgattat tggcaacgcc atgacccgtg
    35041 gaaatccgtg tgtggaagcg gtactggaaa aaaacatccc ttatatgtca ggtccgcagt
    35101 ggctgcacga ttttgtgctg cgcgaccgct gggtgctggc cgttgccggt acacacggca
    35161 aaactaccac cgcgggaatg gcgacctgga ttctggaaca gtgcggttac aaaccgggat
    35221 ttgtgatcgg cggtgtgccg gggaactttg aggtttcggc gcgtctgggc gaaagcgact
    35281 tctttgttat cgaagcggat gagtatgact gcgccttctt cgacaaacgc tctaaatttg
    35341 tccattactg cccgcgtacg ctgatcctca acaaccttga gttcgatcac gccgatatct
    35401 ttgacgacct gaaagcgatc cagaaacagt tccaccatct ggtgcgtatc gttccggggc
    35461 agggccgtat tatctggccg gaaaacgaca tcaacctgaa acagaccatg gcgatgggct
    35521 gctggagcga gcaggagctg gtgggtgagc agggtcactg gcaggcgaaa aagctgacca
    35581 ccgatgcttc cgaatgggaa gtcttgctgg atggcgaaaa agtgggcgaa gtgaaatggt
    35641 cgctggtagg cgaacataat atgcacaatg gcctgatggc gattgcggcg gctcgccatg
    35701 ttggtgtagc gccggcagat gccgctaacg cgctgggttc gtttattaac gctcgccgcc
    35761 gtctggagtt gcgtggtgaa gcgaatggcg tcacggtata tgacgatttt gcccatcacc
    35821 caacggcgat tctggcaacg cttgcggcgc tgcgtggcaa agttggcggt acggcgcgca
    35881 ttattgccgt gctggaaccg cgctcgaata ccatgaaaat ggggatctgc aaagacgatc
    35941 tggcaccttc attaggtcgt gccgatgaag tcttcctgct gcaaccggcg catattccgt
    36001 ggcaggtggc agaagtggca gaagcctgcg ttcagcctgc acactggagt ggcgatgtgg
    36061 atacgctggc agatatggtg gtgaaaaccg ctcagcctgg cgaccatatt ctggtgatga
    36121 gcaacggcgg ttttggtggg atccatcaga aactgctgga tggtctggcg aagaaggcgg
    36181 aagccgcgca gtaattcggc cttagcctga tatagtgtgc gtaggccgga taaggcgttc
    36241 acgccgcatc cggcatttga gcatagtgcc tgatgcgacg cttgatgcgt cttatcaggc
    36301 ctacaggtgc accgcatccg gcaaaccata ctcacatcaa caacgaaaat tacccttcat
    36361 tctccgccag ttcgcgcaga tactggaaaa tctggcgtgc ggatttcggc ggcttattcc
    36421 cttctttctc tttcttcgcg ttgcggatca gagtacgcag ctgctgacga tcggcatcgg
    36481 gccacagatt caatacttca gcgatggcgt catcaccttg atcgatcaga cgatcgcgca
    36541 ggttttccag tttatggaac agcaccacct gctggttgtg acggtttttc agcttatcca
    36601 gcgcctgacg aataggctct acgtcgcgct ggcgcagcat cttaccgatg agctgcaact
    36661 ggcggcggcg accttccatc ttaatacgct gggcgagctc aatagccgcg cgcagatccg
    36721 catctaacgg gatcttatcc agcgcgtttt tccccagatc aacaatttcc gcgccaaggc
    36781 gttttagctc ctcggcatca cgtttaattt cacttttact gacccagata atttcatcgt
    36841 cttcgtcttc gatgtcatca ccgggaacgt cgtcgagcca gtcttcgggc tgcttagtca
    36901 tctcaggctc cttaaaaaaa gaggctaatg ttaccagtta agatgcgcac tgaaaaacgg
    36961 ttctctgtta gacttcagag aaactctcta cattatggca cttgcaatga aagtaatctc
    37021 tcaagttgaa gcgcagcgca agattctgga agaagcagtt tccactgcgc tggagttggc
    37081 ctcaggcaaa tcggacggtg cggaagttgc cgtcagcaag accaccggca ttagcgtaag
    37141 cacgcgttat ggtgaagtgg agaatgttga attcaatagc gatggcgcgc tggggatcac
    37201 tgtttatcac cagaaccgca aaggtagcgc atcatccacc gatttaagcc cgcaggccat
    37261 tgcccgcacc gtacaggcgg cgctggatat tgcccgttat acctcgccag atccctgtgc
    37321 cggcgtggca gacaaagagc tgctggcctt tgacgcaccg gatctcgatt tgttccaccc
    37381 tgcggaagtt tccccggatg aagccattga actggcggcc cgcgcagaac aggcagcatt
    37441 gcaggcggac aaacgcatca ccaataccga aggcggtagc tttaacagcc actacggtgt
    37501 caaagttttt ggcaacagcc acggcatgtt gcagggttac tgctcaacgc gtcattcgct
    37561 ctccagctgt gtaattgccg aagaaaatgg cgatatggag cgtgattacg cctacaccat
    37621 tggtcgtgcg atgagcgatc tgcaaacgcc agagtgggtt ggggccgact gtgctcgccg
    37681 tactttatcg cgcctgtcac cgcgtaaact ctccaccatg aaagcgccgg tcatttttgc
    37741 caatgaagtg gcaaccgggc tttttggcca tctggtgggg gcgatagcgg gtggatcggt
    37801 ttaccgtaaa tccaccttcc tgctggattc gctgggtaaa caaattctgc cggactggct
    37861 gaccgttgaa gagcatccgc atctgctgaa agggctggca tcgacgccat ttgacagcga
    37921 aggtgtgcgc accgagcgtc gcgatattat taaagatggc atcctgactc agtggctgct
    37981 gaccagctac tcggcgcgga aactggggct gaaaagcacc ggacatgcgg gcggtattca
    38041 caactggcgg attgccggac aagggctaag cttcgaacaa atgctcaaag agatgggtac
    38101 cgggctggtg gtgacggagc tgatgggcca gggcgtgagt gccattaccg gtgattattc
    38161 ccgtggtgca gcgggcttct gggtagagaa tggcgaaatt cagtatccgg ttagcgaaat
    38221 caccatcgca ggtaatttaa aagatatgtg gcgcaatatt gtcaccgtcg gtaacgatat
    38281 tgaaacacgc agtaatatac agtgtggttc tgtgctgttg ccggagatga aaatcgccgg
    38341 gcagtaaaaa actggcgcga cctgccgcgc tataaactaa aaaattacac aaaatcattc
    38401 gcactgcatc gagacggaaa gtgaatgagg gccggggagc gtactcgcag tacgtgaccc
    38461 gggcgaatga gcgtagccgt cgatgaggca gtgtgaagga tgaagtgtaa ataaaaaagg
    38521 aagtgagcaa tgcgtaaaag cctgttagct attcttgcag tctcctcgtt ggtattcagt
    38581 tctgcgtcgt ttgccgctga tcttgaagac aatatggaaa ccctcaacga caatttaaaa
    38641 gtgatcgaaa aagcggataa cgcggcgcaa gtcaaagacg cgttaacgaa gatgcgcgcc
    38701 gcagcgctgg atgcgcaaaa agcaacgccg ccgaagctcg aagataaatc accggacagc
    38761 ccggaaatga aagatttccg ccacggtttc gacattctgg tcggtcagat tgacgacgcg
    38821 ctgaagctgg caaatgaagg taaagtaaaa gaagcgcagg ctgctgcaga gcaactgaaa
    38881 acgacccgca acgcctatca ccagaagtat cgttaattcc tcatttccct gttgcctgca
    38941 ctcaggtaac agggaactta tcatcgcaaa tgatgcacca cctgattgct gctgccgcgc
    39001 cagatcaggg aagggtcttt taaatcctgc acaaatttgc cgtcgaccag tacgttaatc
    39061 aaatcaacaa cctgcatttg cgcagcgttg agttcgtcga gtttatagcc tgtccacacc
    39121 cagatgtctt tacccggaca ctcggcgcgg atgcgtttta ccagtttcag aatatccggc
    39181 acgttttgcg gatgcagcgg atcgccgccg gagagggaaa tcccctggcg tttgatacga
    39241 gtgtcattca gatctttaat gatcttgtct tccattgctt tggtaaatgg ctgaccagaa
    39301 tttacccgcc atgtgctttt gttatagcaa ccggggcatt catgaacaca cccggagaca
    39361 aacagggtgc agcgagtgcc ggggccgttg acgatgtcga caggatagta ctgatgataa
    39421 ttcattattt cgcctggctt atcagtccgc gtgtaggctg catccggtaa tcaatgcctg
    39481 atgcgacgct gtcgcgtctt atcaggcctg gagccgttgc caaatgtagg ccggataagg
    39541 cgtttacgcc gcatccggca tttgctttgc gcagagtgaa gattaaccta tctgcccatt
    39601 ccccaaatgt ttaacgcggc gcttaacttc ttcctgctta ccagcgttaa acggacgtgc
    39661 atccgggcta cctaaatatc cgcacacgcg gcgagtcacc gacacacggg aggcgtcatg
    39721 gttaccacat ttcgggcaag tgaagccttt gctggtgcac tcgaactcac cggtaaagcc
    39781 acactcgtag cactcatcaa tcggtgtatt ggtgccgtaa tacggtacat gctgatagct
    39841 gtaatcccag acatcttcca gcgccttcag gttgtgctga atgtttggat actcgccgta
    39901 gcaaatgaaa ccaccgttcg ctagcggcgg gtaaggcgct tcaaagtcga tcttgtcgta
    39961 cgggttcacc ttcttctcca catcgaggtg gaaactgttg gtgtagtaac ctttatcggt
    40021 cacgcccggc accacgccaa actcagcagt atcgagacgg cagaagcggt cgcacaggtt
    40081 ttcactcggc gtgctgtaga gactgaaacc ataacccgtt tcttctttcc actgatccac
    40141 tgcctggcgc agacgttcaa caatggcgat acctttcgcg cgaagctgct cgttgtcgta
    40201 aacatgctcg ccgccgaaca gcgcgttaat ggtttcgtgg atgccgatgt aacccagcga
    40261 aatagacgca cgaccgtttt tgaagatttc agaaacatca tcgtcagcat tcagacgtac
    40321 gccacaagca ccttccatat agaggatcgg ggcgacgcgc gctttcacgc cttcgagacg
    40381 agcgatacgg gtcatcagtg ccttacgtgc cagcaccaga cgttcatcca gcagcttcca
    40441 gaaggtggct tcatcgcctt ttgcttccag agcaatacgc ggcaggttca ggctgatcac
    40501 gccgaggttg ttacgaccat cgtggatctg ctcgccgttt tcattttccc acacgccgag
    40561 gaagctgcgg cagcccatcg gggttttaaa cgaaccggtg actttcacta cctgatcgta
    40621 gttcaggata tccggataca tgcgcttgct tgcgcactcc agcgccagct gtttgatgtc
    40681 gtagttcgga tcgccttttt tatggttcag gccatcgcga atcgcaaaca ccagtttcgg
    40741 gaacaccgca gttttacggt ttttaccaag gcctgcgata cggttacgca ggatagattc
    40801 ctgaatcagg cgcgattccc agctggtgcc cagaccaaaa ccaaaggtta caaacggcgt
    40861 ctgaccgttg gcggtgtgca gggtgtttac ttcgtactcc agcgactgga aggcatcgta
    40921 gcactcttta atggtacgag agttagcgta gccttcggcg tccgggatgt tccactcttc
    40981 tgcggtcttg cgatgtttgt tgtagctggc ggtgacaaac ggtgccagca cttcatcgat
    41041 acggttaatg gtggtgccgc cataaatatg gctggcgacc tgagcaataa tctgcgcagt
    41101 tacagcggtt gccgtagaga tcgacttcgg cggttcaatc tcggcgttcc ccattttaaa
    41161 gccctgggtc agcatgcctt tcaggtcaat caacatgcag ttgaacatcg ggaagaacgg
    41221 cgagtaatcg agatcgtgat agtgaatatc gccacgctca tgtgcctgca ccacgtcacg
    41281 cggcagcagg tgctggcgtg catagtgttt agccacgatc ccggccagca ggtcgcgctg
    41341 ggttggaatc accttgctgt ctttgttggc gttttcgttg agtaacgagg cgttggtctg
    41401 ctcgaccaga ccacggatct cctggttcag gcgaccgcgt ttttcacgtt caatgtcgcg
    41461 atcgtgacgg tactcgatgt aagcacgagc cagttgtttg tatggacccg acatcagctg
    41521 gttttcaact gcggtctgga tctcgttgat atccacctgg ttgcggccct gcatctgctc
    41581 gctgacaacc gcagcaacag tggcgcaata atcggcatca tcgacttccg ctgctttagc
    41641 tgcacgcaga atcgcttctt tgatgcgctc tgatttaaac ggcactttgc agccgtctcg
    41701 tttcatcaca tgcggtgtca tgatcgctcc atatttttaa gaacaggtta tccacagaaa
    41761 ttgggaaagg cgttttccgg ttttttcgtt tcgttttccg gtgctttccg caatcgccat
    41821 ccgcttatcc acaacgccgc acctttttcg tggggagctg tagtagcaat tatagtcgat
    41881 taatacaaca tattgggttg ggacgcattt taaagtctat atatagtgct ttgcatcaag
    41941 gatgtttgaa ctttttttga tgtagctcaa agtaaaaagc agagcgtacg gatgacgggc
    42001 gctacagcgt tatgtaaatt ttttaatgaa tttgctggtt gaaaaatcaa caaaaacaac
    42061 atgctgacag acaaaacccc ggaatgaccg gcattaccgg ggcttaggga agatttactt
    42121 ctgtaaccac cagacagcct caaaaggccg taaattcatg gcacagggtt gtggtgaggc
    42181 ttcttcgtag ttatgcatca caagctgcca gttgccgcgc atttgccctg gctgccaggg
    42241 ttggatccca cggctaaggt tggcaatgac cagcaaggtt tgccccttcc attcacggcg
    42301 atagcaccac aatacagggc tgtttggcag cagatcctgg taattgcccc atgtcagaac
    42361 ggcttcttgc ttacgcagtg cgattaactt ttggtaggtg taaaacaccg aggactcatc
    42421 ggtcagcgcg gcttctacgt tgatttgttg atagttatcg cccaggccaa tccacggttc
    42481 gccagccgta aacccggcat tatcgccgtt gctccattgc atgggcgtgc gactgttgtc
    42541 acgggattta ctggcgagga ttgccaataa ctcgtcggca tcacgcccat tgttgcgcag
    42601 ctcggcaaac atattgaggc tctccacgtc gcgatagtca gtaatgcgcg tgaaatgcgg
    42661 gttggtcatg ccaatctctt cgccctggta gatatacggc gttccctgca tgccatgcag
    42721 caccatcgcc agcatttttg ccgcaggcac gcggtattca ccttcatcac caaagcgaga
    42781 aacaatgcgc ggctgatcgt ggttacacca gaacaaggca ttccatgcca cgttgtgcat
    42841 tccttgttgc cagtggcgga acaatgtttt caacgccaca aagtcaggtt tagccagcgt
    42901 ccatttttca ccaccgggat aatcgacctt caggtgatga aaattaaagg tcatcgacaa
    42961 ttcactgcct gtcagtgccg cgtatcgctg gcaatgctca aggctggtgg aggacatttc
    43021 acctacggtc attaacccgc gtggcgtaaa cacatcgcgg ttcatctcgt gcaaaaactc
    43081 gtgtgctcgt ggcccgtcgg tgtagaagcg acgcccgtcg ccatccaggt cttcagggaa
    43141 acgcgggtct ttggagatca gattcaccac atccaggcgc aacccgtcga ccccacgatc
    43201 ggcccagaat tcacagactt ttttcagctc tgcgcgtacc gctggattct cccagttgag
    43261 atccgcctgt tctggtgcaa agagatgcaa atagtactgt tcgctttccg catgccagcg
    43321 ccacgcacta ccgccaaatt ttgaacgcca gttgttcggt ggcgtttctg gttcgccatc
    43381 gtgccagata taaaactggc ggtaagggct ttctttgttc agcgcctcgc gaaaccaggc
    43441 atgttgggta gaggtatggt taaacaccat atcgagaatg atacgaatcc cgcgcgattt
    43501 tgcctgcgtc accagttcgt caaaatcgtc cagcgtgccg taggtgggat caatcgccgt
    43561 atagttcgct acatcgtaac cgttatcgac ctggggagag acataaaagg gggttagcca
    43621 gatggcatca acgcccagtt tatgcagata gtccaggcgt tggataacgc cacgtaaatc
    43681 gccggtgccg ctacccgtgg tgtcctgaaa actctttgga taaatctggt agataacgcc
    43741 gttttgccac cagtggggaa gattagtcat tacgttattc ctgcaaatgc gagggggcgc
    43801 aattgcgccc cgaagaaaat taaacaatgt ccagcgtgcc caggcggtat ttccgctgat
    43861 agataaacga ggtgagtaca atcgggatga tgatggcgat agccattgcc agcgcaaaca
    43921 cctgccagta gctcggttga atcgagagaa ttcccggcag gccgcctacg ccgataccat
    43981 tcgccataac gccgttcagg ccgcatagca atcctgccag accagaacca atcatcgcgc
    44041 acagcatcgg gaagcgatat ttcaggttga tgccgtacat tgcaggctca gtgaccccaa
    44101 gccaggcgga gatagcggca ggcacggaga tctcgcgctc attgtgcttg cggctggaaa
    44161 tgataatgcc tattacggcg gagccctgag cgatattcga cagcgcaatc agcggccaca
    44221 ctggcgtgcc acccatgctt tgaatcatct gcaaatcaat agcaagggtg gtctggtgta
    44281 cgccggtgat caccagcggc gcgtacagga agccaaacaa tgccgcacca atcggagcaa
    44341 agctgccggt catcaggtga cgtaccgcaa aggcaacgcc atcgccaatc atgcgaccaa
    44401 acggaccaat cagcgcatgg gcgaggaaca ccgcgaggat cagcgaacag acgggtacca
    44461 ccaccagata gaggtaatcc ggcacgatgc gtttaaggcg agtttcaata acgcccagcg
    44521 ccagtccggc taacagtgcc gggatcacct gcgcctgata gcctactttg gcgatgctga
    44581 acatgccaaa gtcccacact tccggcagct gctgcccgag cagataagcg ttcatcagct
    44641 gtggagaaac cagtgtcacg ccaagcacga taccaaggat cggcgtgccg cccatttttt
    44701 tcaccgctga ccagcaaata ccgaccggca ggtagaagaa gatcgcttca ccgatcaacc
    44761 acagaaaatc gtagatcgtt tgcagggaag ggtacatttg cgccagcgtc tgaccgttgc
    44821 tcatgggcaa atcgccgatc acattgcgaa aaccgaggat caaaccgccg ctgatcaacg
    44881 cgggcagcaa cgggaagaag atctccgcga aatgagagat caactgctca tgccatttca
    44941 tattctgccg ggcggctttt tttacctgct ctttatcaac ctgcgcctgt ccggttgacg
    45001 ctattagtgc ttgatagtaa tcacccacat tggtgccaat caccacctga aattgcccgg
    45061 cattggtgaa acagcctttc accatgggga gttgctcaat ttctttcggt ctggcattgg
    45121 ccggttggtt gaggacaaag cgcaggcgag taatacagtg gctcaccgtc gcaatattgc
    45181 cgcgcccgcc gaccagttca atcaaccgat cgatatccgt ttggtttatt ttgctcatca
    45241 taaagcccca tggcagatga catttttggt tggctgcaga atatattgcg cggaaaaatt
    45301 taaaaacggg aacgttcccg aaacgcagcg aagatcacaa tttatcgttc aggaaacgat
    45361 caggacaggg tggcggggat gatgatttgt tgcggttcgc tgcgcccggt tacctgtgcg
    45421 atcaattggc aggccgcctg gcgtccagct tcggcgtaac caggatctac ggtgacgatc
    45481 tccggatgaa ggaatttcat taatggcgta ttaccgacgc tcgccagttg caaggtgtcg
    45541 atgcgttgct cttgcaggta tttacttgcg ccaagtgcca gcgtgtcggt tgcgcacagt
    45601 aaggcggtag tttcaggcgt aatcactttt gctacgttct catagccttg cttcatagca
    45661 aggcctggca gagcggcaac gggatgcagt ttatgcgctt tgcagaacgc caggtaggct
    45721 tcgtgacgtc gcttcccggt cgtcacgtca ctatgcggca cgccgagata actgatatta
    45781 cgatgcccct ggtcatacag ccgttgcatc aggatcttga ttgccccttc gtcgtcataa
    45841 cagaccgaag caaaaccttt tgcgtcacgc gccagcagaa ccagcgatga ctgccagtgg
    45901 gctaacattt cttctgttat gccagtaaaa ccgaacagca ctacgccgtc gatattacgc
    45961 cgtttcagca cccccaaatg ttcggcaact aattgcgggg aaaactgact ttccatcatg
    46021 attgggtcgt aaccttgttc atagaacgct ggcagcatgg tttgaacggc gagattttct
    46081 gacaacgaat ccaggcgggt aacaatgatg gcgaccactt tatcgctttg cccacgcata
    46141 gcgcgcgcag agcgggaagg ggaaaatcca tgctgattca tcactgcttc aacacgctcg
    46201 cgggtgcgct ggctcacgcc gctttcgtta ttcagcaccc gggaaactgt agatttcccc
    46261 acgccgctta agcgtgcgat gtctttgatg gtcagccgat tttgcatcct gttgtcctgt
    46321 aacgtgttgt ttaattattt gagcctaact ttacccgtgc attcagcaat gggtaaagtc
    46381 tggtttatcg ttggtttagt tgccagcagg tattatatcg ccatagatgc tacgaatatt
    46441 attggattct ccttattatt tgcggcgctt ttttcactta ccggaggtta tatggaacct
    46501 gatcccacgc ctctccctcg acggagatta aaacttttcc ggtaagcccg tcttttcacg
    46561 gcttaccgga tgcgtaaggc cgtgacgttt taacgtccct gctcagcttt attaccttca
    46621 ggtaaggctt cgccacgcct gaagacattt ctgtactgtt tcagacagtg cggagggact
    46681 ccttatgttt aaagaaatct ttacccggct cattcgccat ttaccttccc gtctggttca
    46741 tcgtgatcca ttgcctggcg cgcagcagac agtgaatacg gtggtcccgc cgtccttaag
    46801 tgcgcattgc ctgaaaatgg cggtgatgcc cgaagaagaa ttgtggaaaa cgttcgacac
    46861 ccatccggaa gggttaaatc aggcggaagt ggaatctgcc cgcgaacaac atggtgaaaa
    46921 taaattaccc gcacaacaac cgtcgccgtg gtgggtacat ttatgggtct gctatcgcaa
    46981 cccctttaat attttactca ccattctcgg cgctatttct tacgccacgg aagatttatt
    47041 tgccgcgggc gttatcgcgc taatggtcgc tatttctacg ttgctgaact ttattcagga
    47101 agcacgttcc actaaagcgg cagatgccct gaaagcgatg gtcagcaata ccgcgacggt
    47161 gctgcgcgta attaacgaca aaggcgaaaa tggctggctg gagatcccga tcgaccagct
    47221 ggtgcccggc gatattataa aactggcggc gggggatatg atcccggcag atttacgtat
    47281 cttgcaggcg cgggatctgt tcgtcgctca ggcgtcgtta accggtgagt ctctgcccgt
    47341 agaaaaagct gctaccactc gccagccgga gcacagcaat ccgctggagt gtgacaccct
    47401 gtgttttatg ggcaccaccg tggtgagcgg cacggcacaa gcaatggtga ttgctacagg
    47461 agccaatacc tggtttggtc aactggcggg gcgtgttagt gagcaggaaa gcgagccgaa
    47521 tgcctttcag caggggatca gccgcgtcag tatgctgctg attcgcttta tgctggtgat
    47581 ggctccggtg gtgttgctta tcaacggtta caccaaaggc gactggtggg aagcggcact
    47641 gtttgcgctt tcggtcgcgg taggcttaac gccggaaatg ttgccgatga ttgttacctc
    47701 gacgctggcg cgcggcgcag taaagctgtc gaaacagaaa gtgatcgtca aacatctgga
    47761 tgctattcag aactttggcg caatggatat tctgtgcact gataaaactg gcaccctgac
    47821 acaggacaaa attgtgctgg agaatcatac cgatatctcc ggtaaaacca gcgaacgcgt
    47881 gctgcatagc gcgtggttga acagtcatta tcagaccgga cttaaaaacc tgctcgatac
    47941 agcggtgctc gaaggtacgg atgaagagtc agcgcgctcg ctggccagtc gttggcaaaa
    48001 aatcgatgag attccgtttg atttcgagcg tcgccggatg tcggtggtag tggcagaaaa
    48061 taccgagcac catcagctgg tttgcaaagg tgcattgcag gaaatcctca atgtgtgttc
    48121 gcaggtgcgt cacaatggcg agattgtgcc gctcgatgac atcatgctgc gtaagattaa
    48181 gcgggttact gatacgctga atcgtcaggg gctgcgcgtg gttgcggtgg cgacgaaata
    48241 cctgccagcg cgtgaaggag attaccagcg ggcggatgaa tccgacctga tcctcgaagg
    48301 atatattgct ttccttgatc cgccaaaaga gacaactgct ccggcactga aggcattaaa
    48361 agcgagtgga attaccgtaa aaatccttac tggcgacagt gagttagttg cagcgaaagt
    48421 gtgccatgaa gtggggctgg acgcgggaga ggtggtcatt ggtagtgata ttgaaacgct
    48481 atctgacgac gaactggcaa atctcgcaca gcgcaccacg ctgtttgctc gtctgacgcc
    48541 gatgcataaa gaacgcattg tgaccttact gaagcgcgaa gggcatgtgg ttggctttat
    48601 gggcgatggt attaatgatg cgcccgcctt acgcgctgcg gatatcggca tttctgtgga
    48661 cggcgcggta gatattgccc gtgaagcggc tgatatcatc ctgctggaaa aaagcctgat
    48721 ggtgctggaa gagggggtta ttgaaggacg tcgcactttc gccaacatgc tgaaatacat
    48781 caaaatgacg gcgagctcca acttcggtaa tgtgttcagc gtgctggtgg cgagtgcttt
    48841 cttgcccttc ctgccgatgt tgccgttaca cttgcttatt cagaacctgc tgtatgatgt
    48901 gtcacaggtg gcgatcccgt ttgataacgt cgacgacgag caaattcaaa agccgcagcg
    48961 ttggaatccg gcggatctgg ggcgctttat gatcttcttc ggaccgatca gctcgatctt
    49021 cgatattctg acgttttgcc tgatgtggtg ggtattccat gccaacacgc cggaaacgca
    49081 aacgctgttc cagtcgggat ggtttgtggt gggcttactg tcgcaaacgc tgattgtgca
    49141 tatgatccgc acccgccgtg tgccgtttat tcagagctgt gcatcgtggc cgttaatgat
    49201 catgaccgtg atcgtgatga ttgtcgggat cgcattgccg ttttcaccgc tggccagtta
    49261 tctgcaactg caggcgctgc cgttaagcta tttcccgtgg ctggttgcga ttctggcagg
    49321 gtatatgaca ttaacccagt tggtgaaagg attttatagc cgtcgttacg gctggcaata
    49381 aagaatcaac tgggcatggt ggcctggatt cgaattgcag acaaagtgag ttttgttcat
    49441 gccggatgcg gcgtaaatgc cttatccggc caacaaattc aataaattgc aggaatcacg
    49501 taggcctgat aagcgtagcg catcaggcga ttttgtgttt gtcatcagac ttaatccggg
    49561 catgatagcc cggatttcca tcaagattag cgacgaacag cgatcgcttc gatctcaatt
    49621 ttcacgtctt tcggcagacg ggcaacttca acgcaagaac gtgccgggaa ggcggcgttg
    49681 tgttcggtga agaaggcttc gtaagtggcg tttacggttg cgaagtcgtt cagatctttt
    49741 acaaacacgg tagttttaac gatgtcgccc actttcagac cagcggcttc gacgatcgct
    49801 tttacgttat ccagcgactg acgtgcctgt gcagcgacgt ctgccggtac ttcgcccgtt
    49861 ttcggattta ccgggatctg accggaggtg atgatcatat tgcccagatc aacgccctgt
    49921 acgtaagggc cgatagctgc cggtgcattt tccgtcgcga tagttttgct catgatttct
    49981 cctttattac agcggtaaaa agtctggctc attataggga gccagacttt tattaccaac
    50041 cgcaattaat tggccagcac cacattatgg gaaaactctt tttcacagta tttgcatttg
    50101 agcgcgatgt cattggcgcg ttttcgcacg gcaaagctgg aagaaaccgg ttcggcatgg
    50161 ctgatacagt tgctgttcgg gcagaccagc acattgtcga tgcgctccgg cagacttggg
    50221 cgcgatttac ccaccacttc atagttgtcg atacggttaa ccgtggcttg cggcgcatac
    50281 aatgccagtt gatctacctg gtcttcactc aaaaaggtat tttcgatttt gatcagatct
    50341 ttgcggccca tctcgccaga aggcaggttc agaccgatgg tgatgcgctg atccgtttcg
    50401 gtcagcttga acagactcaa cagcttaaaa ccgatctggg cggggatatg gtcaattacc
    50461 gtgccgcgtt taatagcttc aacctgcaat ttattatcgt gtgtcatctc tatttcccct
    50521 tacagtacca gatcgcgatt cagaaccagt gccagtaacg cctggcgagc gaaaatcccg
    50581 ttgcctgcct gctggaagta ccaggcgtgt ggcgttttat caacatccgt cgcaatctca
    50641 tcaacacgcg gcagcggatg aagtactttc atattggctt tggcgttgtg gagatcgctg
    50701 gcgcgaagaa caaactgcgc tttcacgttg gcgtactcgg acgggtccag acgctctttt
    50761 tgcacgcggg tcatgtacag gatgtcaact tccgccatca cttcttcaat agagctgtgc
    50821 agactccatg cgatcccttt ttcatcaagc atatccagaa tgtattgcgg cattgccagc
    50881 gcgtccggcg cgatgaagta aaaacggttg ccgtcgaact tcgctaacgc ctgagtcagg
    50941 gagtgaacgg tgcggccata tttcaggtca ccaaccattg cgacgtggag attgtccaga
    51001 cgcccctggg tttcctgaat ggtgaataag tccagcaagg tttgcgtcgg atgttggttg
    51061 gagccatcac cggcattcag taccggtaca ttgccggaaa actcggtggc caggcgcgcc
    51121 gcaccttcct gcggatgacg catcactatc gcatcgacgt aagtgctgat aaccgaaatg
    51181 gtatcggcca gcgtttcgcc ctttttaccc agtgatgtat tggcgctgtc ggagaagccc
    51241 accacgctgg caccaaggcg gtgcatggaa gtttcgaaag agaggcgggt acgggtagag
    51301 gcttcgaaga aacagctggc aatgactttg tgcttcaaca gctctggttg cgggtttgct
    51361 ttcagtttcg ccgctgtcgc cagcaccaga ttaaggtcat cgcgactaag gtcgtttatg
    51421 gaaatgatat gtttctgata tagcggatta gccatctttt atctcctgac gcctgggcaa
    51481 aaaaaagccc ctcgattgag gggctgggaa tgggtgatca acgggaagaa aaacggcagg
    51541 ccagcgtctt ttttcagacg cggtaagaca aaatgtcgaa cacactgaac catacatcct
    51601 cccggcaaat tgtccggcat tatactcatc gtcagaagcg gtgcaagcat ttgatgcaat
    51661 attttgtcag cgcaaacggt ttatttgaat tataagtcaa aatatatgca tttttattta
    51721 ctgtgattct ggaggggaac tgtcgttcgg tatcaataat tgcagacatt tcctgctttt
    51781 ttctttttca ctttcacgca atcagatatg cattttattc cattcatccg acttataggg
    51841 cggagtgtga aaacgaacgg ctaacactat tgcttacagc tcagggatgc gcgctatcac
    51901 tttaatttca aaatcaaagc ctgccagcca tgtaacgccc accgccgtcc aggttggata
    51961 aggtggcgcg ctaaatattt catttttcac tgtcatgatg tcttcaaatt gtttttctgg
    52021 atcggtatga aagctcgtaa catcaatgat atcgtcaaaa gtgcatcccg cagctgccag
    52081 ggtcgcatgc aaattatcaa atgccagtct gacttgttgc tgaaaatcgg gttctggtgt
    52141 tccgtcctct cgacttccta cttgcccgga aacaaacagc aaatcgccgg aacgaatagc
    52201 cgcagaataa cgatgttctg catacagtga atgtcggcca gcagggaaaa cagcggttct
    52261 ttctaccatt tggttatcct caagatttac gacatgaaca gaagatttat atttaccagg
    52321 agccgctttt agcggacgac gtgagtaaac aaaacccaga catcatggga aatggctggg
    52381 cttaattgag cgtagtcggt tatgcgccaa acgcgccatc aatggtatgc atcgcgccgg
    52441 taacaaaact ggcttctggc cctgctaacc atgcgaccat accagcgacc tcttccggtt
    52501 gcccatgtct tttgatagcc ataaaactat gcaacatatc gcgcattggc ccgttggcgg
    52561 gattagcgtc ggtatcaatt ggccctggct ggacgacgtt gatggtgatc ccacgcggtc
    52621 cgaaatcacg ggccagcccg cgcgccatgc cttgtagggc agatttgctg gcggcataag
    52681 cagccatgcc tgcaacaggc atacgatcgc cattcacgga gccgatgatt aagatgcgcc
    52741 cgccttcggg catctgccgg gcggcttcaa cagaggcatg ataaggagca tgaatattga
    52801 ttttgaaaag gcgatcaata tcgtcggcat ttaattccag ggcctcgcca aagacgccaa
    52861 tacctgcatt taccaccagg atatccaatg cgccgctctt acgaacgaca tcaatgacag
    52921 cgtctctgtc agcactatct gtgaatactg ctgtcgctcc agtctcttgt gccaggcgtt
    52981 tagcggcatc tttcgacccc gcataggtga atcgtacatt ggccccatcg gtgacgaaac
    53041 gacgtacgat agcggcaccg ataccacgac tgccaccgag gatgagaact gtcttacctg
    53101 taaaagcgcc cataaggact ccttgattta ttatgtaaca tgcattacaa aactgtttta
    53161 actttctgtc aacaagtttt gtaatggtca ctaaaaaaca atctcgcgtt ccaggtcgtc
    53221 ccagacgttt cgctcctgag caggcagtct ctgcggcaaa agtgcttttt caccaaaaag
    53281 gtttcgatgc tgtcagtgtt gctgaagtta ctgattatct tggtattaac cccccgagcc
    53341 tctacgcggc ttttggcagt aaagctgggt tatttagccg tgtactcaat gaatacgtcg
    53401 gtacggaagc tattccgctt gccgatattc ttcgtgatga tcgtccagta ggcgagtgcc
    53461 tggttgaggt attaaaagaa gcggcgcgca gatatagcca aaacggcggc tgcgctggct
    53521 gtatggttct tgaaggtatt catagtcatg atccactagc gcgtgatatt gccgttcaat
    53581 attatcacgc cgcagaaacg accatttatg actatatcgc caggcggcat ccacaaagcg
    53641 cacaatgtgt gactgatttt atgagtaccg tgatgtcagg gctttctgcg aaggcacggg
    53701 aggggcactc aatcgaacaa ctctgtgcaa cagctgcact ggcgggggaa gcgataaaaa
    53761 ctcttctcaa ggagtgatgc tggccttgat ccgaaaggcg ggaacgcgcc tgccgataag
    53821 ttgtgataag acaataattc acgcgttaag gctggcggaa ttgatcatct tttcgtataa
    53881 cgatagaaat gaaacattgt tttaattaag gagtggaaaa gatgatcatc ggaaatattc
    53941 ataatcttca gccgtggcta ccccaggagt tacgccaggc gattgagcat atcaaagcgc
    54001 acgttacggc agaaacgcca aagggtaagc acgatatcga aggcaatcgt ctgttttatc
    54061 ttatctcgga agatatgacc gagccgtacg aagctcgccg tgcggagtat catgcccgct
    54121 atctcgacat tcagattgtg ttaaaaggtc aggaaggcat gaccttcagc acgcaacctg
    54181 caggcacgcg ggataccgac tggttagctg ataaagacat cgcatttttg ccggaaggcg
    54241 ttgatgagaa aacagttatc cttaatgaag gtgattttgt tgtgttttat ccgggggaag
    54301 tgcataaacc gctgtgcgca gtgggcgcgc cagcccaggt tcgcaaagca gtagtgaaga
    54361 tgctgatggc gtgatgactt ttcgccgtaa ataactccag gtttacggcg agtttgtgaa
    54421 aagagcgttt tttgatattt ttttgtgagt agaatttgta atgcttagac gttcttatta
    54481 actcaaggag tccgtcatga gcaaaatatc aggttggaat ttttctcaaa acattacatc
    54541 agccgacaat tgtaaacaaa aaaatgaaga cttagatacc tggtatgtgg gaatgaatga
    54601 ttttgcccga attgccggag ggcagaatag cagaagcaat attctttctc ccagagcatt
    54661 tttggagttt ttggctaaga tatttaccct gggttatgtg gattttagca aacgctccaa
    54721 cgaagcgggt agaaatatga tggctcatat taagtcctca tcttatatca aaaataatga
    54781 tggtagtgag ataatgaagt ttgttatgaa taatcctgaa ggggagcgag cggatttatc
    54841 taaggtggaa atagaaatta cacttgcctc agcttttaat aatgggattc gtgaaggaca
    54901 tacagtcatt atatttacac aacctgatgg ttcgactaat cgttatgaag ggaagtcctt
    54961 tgaaagaaaa gatgagagtt cattacacct gattactaac aagattctgg cgtgttacca
    55021 acgcgaagct aacaaggaaa tagctcgtct attaaatatt ccgcaggagt taaataattc
    55081 tcaggacttg aataactcgc aggtgagttg taaagattca gttgattcta cgattacgga
    55141 tttattagaa aaaccattga ataatgcatt attagcaata aggaaagaac atctgctatt
    55201 aatgccttat gtatgtaatg aatcgatttt atacttgctt ggtgaaaaag ggatactgaa
    55261 agaaatagat gaccttaacg cagtaaataa ttatcttctt aataataaga aagctactga
    55321 caatgaaatt aatgacatca aagttaacct gtctcatatt cttattgatt ccttagatga
    55381 tgcaaaagtt aaccttacac cggtcatcga ttcgattctg gagatttttt taaaattccc
    55441 atatattaat gatgtaagaa tactggattg gtgttttaat aaaagaatgc aatattttgg
    55501 tgattctgaa aagataaagt atgcatgctc cgtgataaat catattgatt ttagccgcga
    55561 tcaatctaaa gattttagct gcgatcaatc taaaattaaa atagctgaga ccttattttt
    55621 caatctcgat aaagaacact ataaaaatag ccgtaaatta caggaattga tttgggataa
    55681 gttggttgca tatgtcaatg attttaactt aagcaatcaa gaaaaatcac gcttaatact
    55741 aaggttattt gatgatgtta agttgctatt taatgaagtg cctgtcagca ttttagtaaa
    55801 tgatattttt ttgaaggatt ttttcatgaa gcaacctgat tttgcgaagt ggtacttcta
    55861 tcaattaatt aagaagt
//
LOCUS       DADXDL010000020        50457 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.020, whole genome shotgun sequence.
ACCESSION   DADXDL010000020 DADXDL010000000
VERSION     DADXDL010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 50457)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50457)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50457
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.020"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            365..688
                     /locus_tag="IRB70_001508"
     CDS             365..688
                     /locus_tag="IRB70_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBC0631434.1"
                     /translation="MQFSTTPTLEGQTIVEYCGVVTGEAILGANIFRDFFAGIRDIVG
                     GRSGAYEKELRKAREIAFEELGDQARALGADAVVGIDIDYETVGQNGSMLMVSVSGTA
                     VKTRR"
     gene            685..1515
                     /gene="amiD"
                     /locus_tag="IRB70_001509"
     CDS             685..1515
                     /gene="amiD"
                     /locus_tag="IRB70_001509"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiD"
                     /protein_id="HBC0631435.1"
                     /translation="MRRVFWLVAAALLLAGCAGEKGIVEKEGYQLDTRRQAQAAYPRI
                     KVLVIHYTADDFDSSLATLTDKQVSSHYLVPAVPPRYNGKPRIWQLVPEQELAWHAGI
                     SAWRGATRLNDTSIGIELENRGWQKSAGVKYFAPFEPAQIQALIPLAKDIIARYHIKP
                     ENVVAHADIAPQRKDDPGPLFPWQQLAQQGIGAWPDAQRVNFYLAGRAPHTPVDTASL
                     LELLARYGYDVKPDMTPREQRRVIMAFQMHFRPTLYNGEADAETQAIAEALLEKYGQD
                     "
     gene            complement(1512..2525)
                     /locus_tag="IRB70_001510"
     CDS             complement(1512..2525)
                     /locus_tag="IRB70_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415389.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBC0631436.1"
                     /translation="MKVLVTGATSGLGRNAVEFLCQKGISVRATGRNEAMGKLLEKMG
                     AEFVPADLTELVSSQAKVMLAGIDTLWHCSSFTSPWGTQQAFDLANVRATRRLGEWAV
                     AWGVRNFIHISSPSLYFDYHHHRDIKEDFRPHRFANEFARSKAASEEVINMLSQANPQ
                     TRFTILRPQSLFGPHDKVFIPRLAHMMHHYGSILLPHGGSALVDMTYYENAVHAMWLA
                     SQEACDKLPSGRVYNITNGEHRTLRSIVQKLIDELNIDCRIRSVPYPMLDMIARSMER
                     LGRKSAKEPPLTHYGVSKLNFDFTLDITRAQEELGYQPVLTLDEGIEKTAAWLRDHGK
                     LPR"
     gene            complement(2624..4054)
                     /locus_tag="IRB70_001511"
     CDS             complement(2624..4054)
                     /locus_tag="IRB70_001511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415390.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2867 domain-containing protein"
                     /protein_id="HBC0631437.1"
                     /translation="MPQRILVLGASGYIGQHLVHTLSQQGHQILAAARHVDRLAKLQL
                     ANVSCHKVDLSWPDNLPALLQDIDTVYFLVHSMGEGGDFIAQERQVALNVRDALREVP
                     VKQLIFLSSLQAPAHEQSDHLRARQATADILREAGVPVTELRAGIIVGAGSAAFEVMR
                     DMVYNLPVLTPPRWVRSRTTPIALENLLHYLVALLDHPASEHRIFEAAGPEVLSYQQQ
                     FEHFMAVSGKRRWLIPIPFPTRWISVWFLNVITSVPPTTAKALIQGLKHDLLADDTAL
                     RALIPQRLIAFDDAVRRTLKEEEKLVNSSDWGYDAQAFARWRPEYGYFAKQAGFTVKT
                     SASLAALWQVVNQIGGKERYFFGNILWQTRALMDRAIGHKLAKGRPEREYLQTGDAVD
                     SWKVIVVEPEKQLTLLFGMKAPGLGRLCFTLEDKGDYRTIDVRAFWHPHGMPGLFYWL
                     LMIPAHLFIFRGMAKQIARLAEQSTD"
     gene            complement(4065..5066)
                     /gene="ltaE"
                     /locus_tag="IRB70_001512"
     CDS             complement(4065..5066)
                     /gene="ltaE"
                     /locus_tag="IRB70_001512"
                     /EC_number="4.1.2.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low-specificity L-threonine aldolase"
                     /protein_id="HBC0631438.1"
                     /translation="MIDLRSDTVTRPSRAMLEAMMAAPVGDDVYGDDPTVNALQDYAA
                     ELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGAAVLGSIQPQP
                     IDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHNGKVLPREYLKEAWEFTRERN
                     LALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSKGLGTPVGSLLVGNRDYIKRAI
                     RWRKMTGGGMRQSGILAAAGIYALKNNVARLQEDHDNAAWMAEQLREAGADVMRQDTN
                     MLFVRVGEENAAALGEYMKARNVLINASPIVRLVTHLDVSRAQLAEVAAHWRAFLAR"
     gene            complement(5103..6821)
                     /gene="poxB"
                     /locus_tag="IRB70_001513"
     CDS             complement(5103..6821)
                     /gene="poxB"
                     /locus_tag="IRB70_001513"
                     /EC_number="1.2.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone-dependent pyruvate dehydrogenase"
                     /protein_id="HBC0631439.1"
                     /translation="MKQTVAAYIAKTLESAGVKRIWGVTGDSLNGLSDSLNRMGTIEW
                     MSTRHEEVAAFAAGAEAQLSGELAVCAGSCGPGNLHLINGLFDCHRNHVPVLAIAAHI
                     PSSEIGSGYFQETHPQELFRECSHYCELVSSPEQIPQVLAIAMRKAVLNRGVSVVVLP
                     GDVALKPAPEGATTHWYHAPQPVVTPEEEELRKLAQLLRYSSNIALMCGSGCAGAHKE
                     LVEFAGKIKAPIVHALRGKEHVEYDNPYDVGMTGLIGFSSGFHTMMNADTLVLLGTQF
                     PYRAFYPTDAKIIQIDINPASIGAHSKVDMALVGDIKSTLRALLPLVEEKTDRKFLDK
                     ALEDYRDARKGLDDLAKPSEKAIHPQYLAQQISHFAADDAIFTCDVGTPTVWAARYLK
                     MNGKRRLLGSFNHGSMANAMPQALGAQATEPERQVVAMCGDGGFSMLMGDFLSVMQMK
                     LPVKIIVFNNSVLGFVAMEMKAGGYLTDGTELHDTNFARIAEACGITGIRVEKASEVD
                     EALQRAFSIDGPVLVDVVVAKEELAIPPQIKLEQAKGFSLYMLRAIISGRGDEVIELA
                     KTNWLR"
     gene            complement(6954..7922)
                     /gene="hcr"
                     /locus_tag="IRB70_001514"
     CDS             complement(6954..7922)
                     /gene="hcr"
                     /locus_tag="IRB70_001514"
                     /EC_number="1.6.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidoreductase"
                     /protein_id="HBC0631440.1"
                     /translation="MTMPTNQCPWRMQVHHITQETPDVWTISLICHDYYPYRAGQYAL
                     VSVRNSAETLRAYTISSTPGVSEYITLTVRRIDDGVGSRWLTRDVKRGDYLWLSDAMG
                     EFTCDDKAEDKFLLLAAGCGVTPIMSMRRWLAKNRPQADVQVIYNVRTPQDVIFADEW
                     RNYPVTLVAENNVTEGFIAGRLTRELLAGVPDLASRTVMTCGPAPYMDWVEQEVKALG
                     VTRFFKEKFFTPVAEAATSGLKFTKLQPAREFYAPVGTTLLEALESNNVPVVAACRAG
                     VCGCCKTKVVSGEYTVSSTMTLTDAEIAEGYVLACSCHPQGDLVLA"
     gene            complement(7934..9586)
                     /gene="hcp"
                     /locus_tag="IRB70_001515"
                     /gene_synonym="priS"
     CDS             complement(7934..9586)
                     /gene="hcp"
                     /locus_tag="IRB70_001515"
                     /gene_synonym="priS"
                     /EC_number="1.7.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxylamine reductase"
                     /protein_id="HBC0631441.1"
                     /translation="MFCVQCEQTIRTPAGNGCSYAQGMCGKTAETSDLQDLLIATLQG
                     LSAWAVKAREYGIINHDVDSFAPRAFFSTLTNVNFDSPRIVGYAREAIVLREALKAQC
                     LAVDANAHVDNPMADLQLVSDDLGELQRQAAEFTPNKDKAAIGENILGLRLLCLYGLK
                     GAAAYMEHAHVLGQYDNDIYAQYHKIMAWLGTWPADMNALLECSMEIGQMNFKVMSIL
                     DAGETSKYGHPTPTQVNVKATAGKCILISGHDLKDLYNLLEQTEGTGVNVYTHGEMLP
                     AHGYPELRKFKHLVGNYGSGWQNQQVEFARFPGPIVMTSNCIIDPTVGAYDDRIWTRS
                     IVGWPGVRHLDGEDFSAVIAQAQQMAGFPYSEIPHLITVGFGRQTLLGAADTLIDLVS
                     REKLRHIFLLGGCDGARGERHYFTDFATSVPDDCLILTLACGKYRFNKLEFGDIEGLP
                     RLVDAGQCNDAYSAIILAVTLAEKLGCGVNDLPLSLVLSWFEQKAIVILLTLLSLGVK
                     NIVTGPTAPGFLTPDLLAVLNEKFGLRSITTVEEDMKQLLSA"
     gene            complement(9729..10628)
                     /gene="lysO"
                     /locus_tag="IRB70_001516"
     CDS             complement(9729..10628)
                     /gene="lysO"
                     /locus_tag="IRB70_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lysine exporter LysO"
                     /protein_id="HBC0631442.1"
                     /translation="MFSGLLIILVPLILGYLIPLRQKAALKVINQLLSWMVYLILFFM
                     GISLAFLDNLASNLLAILHYSAVSITVILLCNIAALMWLERGLPWRNYHQQEKLPSRI
                     AMALESLKLCGVVVIGFAIGLSGLAFLQHATEASEYTLILLLFLVGIQLRNNGMTLKQ
                     IVLNRRGMIVAVVVVASSLIGGLINAFILDLPINTALAMASGFGWYSLSGILLTESFG
                     PVIGSAAFFNDLARELIAIMLIPGLIRRSRSTALGLCGATSMDFTLPVLQRTGGLDMV
                     PAAIVHGFILSLLVPILIAFFSA"
     gene            complement(11086..11781)
                     /gene="aqpZ"
                     /locus_tag="IRB70_001517"
     CDS             complement(11086..11781)
                     /gene="aqpZ"
                     /locus_tag="IRB70_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin Z"
                     /protein_id="HBC0631443.1"
                     /translation="MFRKLAAECFGTFWLVFGGCGSAVLAAGFPELGIGFAGVALAFG
                     LTVLTMAFAVGHISGGHFNPAVTIGLWAGGRFPAKEVVGYVIAQVVGGIVAAALLYLI
                     ASGKTGFDAAASGFASNGYGEHSPGGYSMLSALVVELVLSAGFLLVIHGATDKFAPAG
                     FAPIAIGLALTLIHLISIPVTNTSVNPARSTAVAIFQGGWALEQLWFFWVVPIVGGII
                     GGLIYRTLLEKRN"
     gene            12207..13865
                     /locus_tag="IRB70_001518"
     CDS             12207..13865
                     /locus_tag="IRB70_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent endonuclease"
                     /protein_id="HBC0631444.1"
                     /translation="MILERVEIVGFRGINRLSLMLEQNNVLIGENAWGKSSLLDALTL
                     LLSPESDLYHFERDDFWFPPGDINGREHHLHIILTFRESLPGRHRVRRYRPLEACWTP
                     CTDGYHRIFYRLEGESAEDGSVMTLRSFLDKDGHPIDVEDINDQARHLVRLMPVLRLR
                     DARFMRRIRNGTVPNVPNVEVTARQLDFLARELSSHPQNLSDGQIRQGLSAMVQLLEH
                     YFSEQGAGQARYRLMRRRASNEQRSWRYLDIINRMIDRPGGRSYRVILLGLFATLLQA
                     KGTLRLDKDARPLLLIEDPETRLHPIMLSVAWHLLNLLPLQRIATTNSGELLSLTPVE
                     HVCRLVRESSRVAAWRLGPSGLSTEDSRRISFHIRFNRPSSLFARCWLLVEGETETWV
                     INELARQCGHHFDAEGIKVIEFAQSGLKPLVKFARRMGIEWHVLVDGDEAGKKYAATV
                     RSLLNNDREAEREHLTALPALDMEHFMYRQGFSDVFHRVAQIPENVPMNLRKIISKAI
                     HRSSKPDLAIEVAMEAGRRGVDSVPTLLKKMFSRVLWLARGRAD"
     gene            complement(13862..14818)
                     /locus_tag="IRB70_001519"
     CDS             complement(13862..14818)
                     /locus_tag="IRB70_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001322270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF535 domain-containing protein"
                     /protein_id="HBC0631445.1"
                     /translation="MNMSQLTERTFTPSESLSSLSLFLSLARGQCRPGKFWHRRSFRQ
                     KFLLRSLIMPRLSVEWMNELSHWPNLNVLLTRQPRLPVRLHRPYLAANLSRKQLLEAL
                     RYHYALLRGCMSAEEFSLYLNTPGLQLAKLEGKNGEQFTLELTMMISMDKEGDSTILF
                     RNSEGIPLAELTFTLCEYQGKRTMFIGGLQGAKWEIPHQEIQNATKACHGLFPKRLVM
                     EAACLFAQRLQVEQIIAVSNETHIYRSLRYRDKEGKIHADYNAFWESVGGVCDAERHY
                     RLPAQIARKEIAEIASKKRAEYRRRYEMLDAIQPQMATMFRG"
     gene            14969..16084
                     /gene="macA"
                     /locus_tag="IRB70_001520"
     CDS             14969..16084
                     /gene="macA"
                     /locus_tag="IRB70_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308991.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide transporter subunit MacA"
                     /protein_id="HBC0631446.1"
                     /translation="MKKRKTVKKRYVIALVIVIAGLITLWRILNAPVPTYQTLIVRPG
                     DLQQSVLATGKLDALRKVDVGAQVSGQLKTLSVAIGDKVKKDQLLGVIDPEQAENQIK
                     EVEATLMELRAQRQQAEAELKLARVTYSRQQRLAQTQAVSQQDLDTAATEMAVKQAQI
                     GTIDAQIKRNQASLDTAKTNLDYTRIVAPMAGEVTQITTLQGQTVIAAQQAPNILTLA
                     DMSTMLVKAQVSEADVIHLKPGQKAWFTVLGDPLTRYEGQIKDVLPTPEKVNDAIFYY
                     ARFEVPNPNGLLRLDMTAQVHIQLTDVKNVLTIPLSALGDPVGDNRYKVKLLRNGETR
                     EREVTIGARNDTDVEIVKGLEAGDEVVIGEAKPGAAQ"
     gene            16081..18027
                     /gene="macB"
                     /locus_tag="IRB70_001521"
     CDS             16081..18027
                     /gene="macB"
                     /locus_tag="IRB70_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="macrolide ABC transporter ATP-binding
                     protein/permease MacB"
                     /protein_id="HBC0631447.1"
                     /translation="MTPLLELKDIRRSYPAGDEQVEVLKGISLDIYAGEMVAIVGASG
                     SGKSTLMNILGCLDKATSGTYRVAGQDVATLDADALAQLRREHFGFIFQRYHLLSHLT
                     AEQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRTEYYPAQLSGGQQQRVSIARALM
                     NGGQVILADEPTGALDSHSGEEVMAILHQLRDRGHTVIIVTHDPQVAAQAERVIEIRD
                     GEIVSNPPAIEKVNVAGGTEPVVNTASGWRQFASGFNEALTMAWRALAANKMRTLLTM
                     LGIIIGIASVVSIVVVGDAAKQMVLADIRSIGTNTIDVYPGKDFGDDDPQYQQALKYD
                     DLIAIQKQPWVASATPAVSQNLRLRYNNVDVAASANGVSGDYFNVYGMTFSEGNTFNQ
                     EQLNGRAQVVVLDSNTRRQLFPHKADVVGEVILVGNMPARVIGVAEEKQSMFGSSKVL
                     RVWLPYSTMSGRVMGQSWLNSITVRVKEGFDSAEAEQQLTRLLSLRHGKKDFFTWNMD
                     GVLKTVEKTTRTLQLFLTLVAVISLVVGGIGVMNIMLVSVTERTREIGIRMAVGARAS
                     DVLQQFLIEAVLVCLVGGALGITLSLLIAFTLQLFLPGWEIGFSPLALLLAFLCSTVT
                     GILFGWLPARNAARLDPVDALARE"
     gene            complement(18100..18324)
                     /gene="cspD"
                     /locus_tag="IRB70_001522"
     CDS             complement(18100..18324)
                     /gene="cspD"
                     /locus_tag="IRB70_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock-like protein CspD"
                     /protein_id="HBC0631448.1"
                     /translation="MEKGTVKWFNNAKGFGFICPEGGGEDIFAHYSTIQMDGYRTLKA
                     GQSVQFDVHQGPKGNHASVIVPVEVEAAVA"
     gene            18647..18967
                     /gene="clpS"
                     /locus_tag="IRB70_001523"
     CDS             18647..18967
                     /gene="clpS"
                     /locus_tag="IRB70_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease adapter ClpS"
                     /protein_id="HBC0631449.1"
                     /translation="MGKTNDWLDFDQLAEEKVRDALKPPSMYKVILVNDDYTPMEFVI
                     DVLQKFFSYDVERATQLMLAVHYQGKAICGVFTAEVAETKVAMVNKYARENEHPLLCT
                     LEKA"
     gene            18998..21274
                     /gene="clpA"
                     /locus_tag="IRB70_001524"
     CDS             18998..21274
                     /gene="clpA"
                     /locus_tag="IRB70_001524"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpA"
                     /protein_id="HBC0631450.1"
                     /translation="MLNQELELSLNMAFARAREHRHEFMTVEHLLLALLSNPSAREAL
                     EACSVDLVALRQELEAFIEQTTPVLPASEEERDTQPTLSFQRVLQRAVFHVQSSGRNE
                     VTGANVLVAIFSEQESQAAYLLRKHEVSRLDVVNFISHGTRKDEPTQSSDPGSQPNSE
                     EQAGGEERMENFTTNLNQLARVGGIDPLIGREKELERAIQVLCRRRKNNPLLVGESGV
                     GKTAIAEGLAWRIVQGDVPEVMADCTIYSLDIGSLLAGTKYRGDFEKRFKALLKQLEQ
                     DTNSILFIDEIHTIIGAGAASGGQVDAANLIKPLLSSGKIRVIGSTTYQEFSNIFEKD
                     RALARRFQKIDITEPSIEETVQIINGLKPKYEAHHDVRYTAKAVRAAVELAVKYINDR
                     HLPDKAIDVIDEAGARARLMPVSKRKKTVNVADIESVVARIARIPEKSVSQSDRDTLK
                     NLGDRLKMLVFGQDKAIEALTEAIKMARAGLGHEHKPVGSFLFAGPTGVGKTEVTVQL
                     SKALGIELLRFDMSEYMERHTVSRLIGAPPGYVGFDQGGLLTDAVIKHPHAVLLLDEI
                     EKAHPDVFNILLQVMDNGTLTDNNGRKADFRNVVLVMTTNAGVRETERKSIGLIHQDN
                     STDAMEEIKKIFTPEFRNRLDNIIWFDHLSTDVIHQVVDKFIVELQVQLDQKGVSLEV
                     SQEARNWLAEKGYDRAMGARPMARVIQDNLKKPLANELLFGSLVDGGQVTVALDKEKN
                     ELTYGFQSAQKHKAEAAH"
     gene            complement(21681..21768)
                     /locus_tag="IRB70_001525"
     tRNA            complement(21681..21768)
                     /locus_tag="IRB70_001525"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(21732..21734),aa:Ser,seq:gga)
     gene            complement(22022..22240)
                     /gene="infA"
                     /locus_tag="IRB70_001526"
     CDS             complement(22022..22240)
                     /gene="infA"
                     /locus_tag="IRB70_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001040186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBC0631451.1"
                     /translation="MAKEDNIEMQGTVLETLPNTMFRVELENGHVVTAHISGKMRKNY
                     IRILTGDKVTVELTPYDLSKGRIVFRSR"
     gene            complement(22525..23229)
                     /gene="aat"
                     /locus_tag="IRB70_001527"
     CDS             complement(22525..23229)
                     /gene="aat"
                     /locus_tag="IRB70_001527"
                     /EC_number="2.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl/phenylalanyl-tRNA--protein transferase"
                     /protein_id="HBC0631452.1"
                     /translation="MRLVQLSRHSIAFPSPEGALREPNGLLALGGDLSPARLLMAYQR
                     GIFPWFSPGDPILWWSPDPRAVLWPESLHISRSMKRFHKRSPYRVTMNYAFGQVIEGC
                     ASDREEGTWITRGVVEAYHRLHELGHAHSIEVWCEDELVGGMYGVAQGTLFCGESMFS
                     RMENASKTALLVFCEEFIGHGGKLIDCQVLNDHTASLGACEIPRRDYLNYLNQMRLGR
                     LPNKFWVPRCLFSPQE"
     gene            complement(23271..24992)
                     /gene="cydC"
                     /locus_tag="IRB70_001528"
     CDS             complement(23271..24992)
                     /gene="cydC"
                     /locus_tag="IRB70_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter ATP-binding
                     protein/permease CydC"
                     /protein_id="HBC0631453.1"
                     /translation="MRALLPYLALYKRHKWMLSLGIVLAIVTLLASIGLLTLSGWFLS
                     ASAVAGVAGLYSFNYMLPAAGVRGAAITRTAGRYFERLVSHDATFRVLQHLRIYTFSK
                     LLPLSPAGLARYRQGELLNRVVADVDTLDHLYLRVISPLVGAFVVIMVVTIGLSFLDF
                     TLAFTLGGIMLLTLFLMPPLFYRAGKSTGQNLTHLRGQYRQQLTAWLQGQAELTIFGA
                     SDRYRTQLENTEIQWLEAQRRQSELTALSQAIMLLIGALAVILMLWMASGGVGGNAQP
                     GALIALFVFCALAAFEALAPVTGAFQHLGQVIASAVRITDLTDQKPEVTFPDTQTRVA
                     DRVSLTLRDVQFTYPEQSQQALKGISLQVNAGEHIAILGRTGCGKSTLLQLLTRAWDP
                     QQGEILLNDSPIASLNEATLRQTISVVPQRVHLFSATLRDNLLLASPGSSDEALAEIL
                     RRVGLEKLLEDAGLNSWLGEGGRQLSGGELRRLAIARALLHDAPLVLLDEPTEGLDAT
                     TESQILELLAEMMCEKTVLMVTHRLRGLSRFQQIIVMDNGQIIEQGTHAELLARQGRY
                     YQFKQGL"
     gene            complement(24993..26759)
                     /gene="cydD"
                     /locus_tag="IRB70_001529"
     CDS             complement(24993..26759)
                     /gene="cydD"
                     /locus_tag="IRB70_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine/glutathione ABC transporter
                     permease/ATP-binding protein CydD"
                     /protein_id="HBC0631454.1"
                     /translation="MNKSRQKELTRWLKQQSVISQRWLNISRLLGFVSGILIIAQAWF
                     MARILQHMIMENIPREALLLPFTLLVLTFVLRAWVVWLRERVGYHAGQHIRFAIRRQV
                     LDRLQQAGPAWIQGKPAGSWATLVLEQIDDMHDYYARYLPQMALAVSVPLLIVVAIFP
                     SNWAAALILLGTAPLIPLFMALVGMGAADANRRNFLALARLSGHFLDRLRGMETLRIF
                     GRGEAEIESIRSASEDFRQRTMEVLRLAFLSSGILEFFTSLSIALVAVYFGFSYLGEL
                     DFGHYDTGVTLAAGFLALILAPEFFQPLRDLGTFYHAKAQAVGAADSLKTFMETPLAH
                     PQRGEAELASTDPVTIEAEDLFITSPEGKTLAGPLNFTLPAGQRAVLVGRSGSGKSSL
                     LNALSGFLSYQGSLRINGIELRDLSPESWRKHLSWVGQNPQLPAATLRDNVLLARPDA
                     SEQELQTALDNAWVSEFLPLLPQGIDTPVGDQAARLSVGQAQRVAVARALLNPCSLLL
                     LDEPAASLDAHSEQRVMEALNAASLRQTTLMVTHQLEDLADWDVIWVMQDGQIIEQGR
                     YAELSVAGGPFATLLAHRQEEI"
     gene            complement(26882..27847)
                     /gene="trxB"
                     /locus_tag="IRB70_001530"
     CDS             complement(26882..27847)
                     /gene="trxB"
                     /locus_tag="IRB70_001530"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBC0631455.1"
                     /translation="MGTTKHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQL
                     TTTTEVENWPGDPNDLTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRLTGDSG
                     EYTCDALIIATGASARYLGLPSEEAFKGRGVSACATCDGFFYRNQKVAVIGGGNTAVE
                     EALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGV
                     TGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFEGQLELENGYIKVQSGIHGNATQ
                     TSIPGVFAAGDVMDHIYRQAITSAGTGCMAALDAERYLDGLADAK"
     gene            28391..28885
                     /gene="lrp"
                     /locus_tag="IRB70_001531"
     CDS             28391..28885
                     /gene="lrp"
                     /locus_tag="IRB70_001531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-responsive transcriptional regulator
                     Lrp"
                     /protein_id="HBC0631456.1"
                     /translation="MVDSKKRPGKDLDRIDRNILNELQKDGRISNVELSKRVGLSPTP
                     CLERVRRLERQGFIQGYTALLNPHYLDASLLVFVEITLNRGAPDVFEQFNTAVQKLEE
                     IQECHLVSGDFDYLLKTRVPDMSAYRKLLGETLLRLPGVNDTRTYVVMEEVKQSNRLV
                     IKTR"
     gene            29020..33090
                     /gene="ftsK"
                     /locus_tag="IRB70_001532"
     CDS             29020..33090
                     /gene="ftsK"
                     /locus_tag="IRB70_001532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBC0631457.1"
                     /translation="MSQEYTEDKEVTLTKLSSGRRLLEALLILIVLFAVWLMAALLSF
                     NPSDPSWSQTAWHEPIHNLGGMPGAWLADTLFFIFGVMAYTIPVIIVGGCWFAWRHQS
                     SDEYIDYFAVSLRIIGVLALILTSCGLAAINADDIWYFASGGVIGSLLSTTLQPLLHS
                     SGGTIALLCVWAAGLTLFTGWSWVTIAEKLGGWILNILTFASNRTRRDDTWVDEDEYE
                     DDEEYEEDESHGKQHESRRARILRGALARRKRLAEKFINPMGRQTDAALFSGKRMDDD
                     EEITYTARGVAADPDDVLFSGNRATQPEYDEYDPLLNGAPITEPVAVAAAATTATQSW
                     AAPVEPVTQTPPVASVDVPPTQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAV
                     QYNEPLQQPVQPQQPYYAPAAEQPVQQPYYAPAPEQSAQQPYYAPAPEQSVAGNAWQA
                     EEQQSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLY
                     YFEEVEEKRAREREQLAAWYQPIPEPVKEPEPIKSSLKAPSVAAVPPVEAAAAVSPLA
                     SGVKKATLATGAAATVAAPVFSLANSAGPRPQVKEGIGPQLPRPKRIRVPTRRELASY
                     GIKLPSQRAAEEKAREAQRNQYDSGDQYNDDEIDAMQQDELARQFAQTQQQRYGEQYQ
                     HDVPVNAEDADAAAEAELARQFAQTQQQRYSGEQPAGANPFTLDDFEFSPMKALLDDG
                     PHEPLFTPIVEPVQQPQQPIAPQQQYQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQQP
                     VAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQDTLLHPLLMRNGD
                     SRPLHKPTTPLPSLDLLTPPPSEVEPVDTLALEQMARLVEARLADFRIKADVVNYSPG
                     PVITRFELNLAPGVKAARISNLSRDLARSLSTVAVRVVEVIPGKPYVGLELPNKKRQT
                     VYLREVLDNAKFRDNPSPLTVVLGKDIAGEPVVADLAKMPHLLVAGTTGSGKSVGVNA
                     MILSMLYKAQPEDVRFIMIDPKMLELSVYEGIPHLLTEVVTDMKDAANALRWCVNEME
                     RRYKLMSALGVRNLAGYNEKIAEADRMMRPIPDPYWKPGDSMDAQHPVLKKEPYIVVL
                     VDEFADLMMTVGKKVEELIARLAQKARAAGIHLVLATQRPSVDVITGLIKANIPTRIA
                     FTVSSKIDSRTILDQAGAESLLGMGDMLYSGPNSTLPVRVHGAFVRDQEVHAVVQDWK
                     ARGRPQYVDGITSDSESEGGAGGFDGAEELDPLFDQAVQFVTEKRKASISGVQRQFRI
                     GYNRAARIIEQMEAQGIVSEQGHNGNREVLAPPPFD"
     gene            33249..33860
                     /gene="lolA"
                     /locus_tag="IRB70_001533"
     CDS             33249..33860
                     /gene="lolA"
                     /locus_tag="IRB70_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010354356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein chaperone LolA"
                     /protein_id="HBC0631458.1"
                     /translation="MKKIAITCALLSSLVASSVWADAASDLKSRLDKVSSFHASFTQK
                     VTDGSGAAVQEGQGDLWVKRPNLFNWHMTQPDESILVSDGKTLWFYNPFVEQATATWL
                     KDATGNTPFMLIARNQSSDWQQYNIKQNGDDFVLTPKASNGNLKQFTINVGRDGTIHQ
                     FSAVEQDDQRSSYQLKSQQNGAVDAAKFTFTPPQGVTVDDQRK"
     gene            33871..35214
                     /gene="rarA"
                     /locus_tag="IRB70_001534"
                     /gene_synonym="mgsA"
     CDS             33871..35214
                     /gene="rarA"
                     /locus_tag="IRB70_001534"
                     /gene_synonym="mgsA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein
                     RarA"
                     /protein_id="HBC0631459.1"
                     /translation="MSNLSLDFSDNTFQPLAARMRPENLAQYIGQQHLLAAGKPLPRA
                     IEAGHLHSMILWGPPGTGKTTLAEVIARYANADVERISAVTSGVKEIREAIERARQNR
                     NAGRRTILFVDEVHRFNKSQQDAFLPHIEDGTITFIGATTENPSFELNSALLSRARVY
                     LLKSLSTKDIEQVLTQAMEDKTRGYGGQDIVLPDETRRAIAELVNGDARRALNTLEMM
                     ADMAEVDDSGKRVLKPELLTEIAGERSARFDNKGDRFYDLISALHKSVRGSAPDAALY
                     WYARIITAGGDPLYVARRCLAIASEDVGNADPRAMQVAIAAWDCFTRVGPAEGERAIA
                     QAIVYLACAPKSNAVYTAFKAALADARERPDYDVPVHLRNAPTKLMKEMGYGQEYRYA
                     HDEANAYAAGEVYFPPEIAQTRYYFPTNRGLEGKIGEKLAWLAEQDQNSPIKRYR"
     gene            35305..36597
                     /gene="serS"
                     /locus_tag="IRB70_001535"
     CDS             35305..36597
                     /gene="serS"
                     /locus_tag="IRB70_001535"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000887397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBC0631460.1"
                     /translation="MLDPNLLRNEPDAVAEKLARRGFKLDVDKLGALEERRKVLQVKT
                     ENLQAERNSRSKSIGQAKARGEDIEPLRLEVNKLGEELDAAKAELDALQAEIRDIALT
                     IPNLPADEVPVGKDENDNVEVSRWGTPREFDFEVRDHVTLGEMHSGLDFAAAVKLTGS
                     RFVVMKGQIARMHRALSQFMLDLHTEQHGYSENYVPYLVNQDTLYGTGQLPKFAGDLF
                     HTRPLEEEADTSNYALIPTAEVPLTNLVRGEIIDEDDLPIKMTAHTPCFRSEAGSYGR
                     DTRGLIRMHQFDKVEMVQIVRPEDSMAALEEMTGHAEKVLQLLGLPYRKIILCTGDMG
                     FGACKTYDLEVWIPAQNTYREISSCSNVWDFQARRMQARCRSKSDKKTRLVHTLNGSG
                     LAVGRTLVAVMENYQQADGRIEVPEVLRPYMNGLEYIG"
     gene            36836..39280
                     /gene="dmsA"
                     /locus_tag="IRB70_001536"
     CDS             36836..39280
                     /gene="dmsA"
                     /locus_tag="IRB70_001536"
                     /EC_number="1.8.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415414.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit A"
                     /protein_id="HBC0631461.1"
                     /translation="MKTKIPDAVLAAEVSRRGLVKTTAIGGLAMASSALTLPFSRIAH
                     AVDSALPAKSDEKVIWSACTVNCGSRCPLRMHVVDGEIKYVETDNTGDDNYDGLHQVR
                     ACLRGRSMRRRVYNPDRLKYPMKRVGARGEGKFERISWEEAYDIIATNMQRLIKEYGN
                     ESIYLNYGTGTLGGTMTRSWPPGNTLVARLMNCCGGYLNHYGDYSSAQIAEGLNYTYG
                     GWADGNSPSDIENSKLVVLFGNNPGETRMSGGGVTYYLEQARQKSNARMIIIDPRYTD
                     TGAGREDEWIPIRPGTDAALVNGLAYVMITENLVDQAFLDKYCVGYDEKTLPASAPKN
                     GHYKAYILGDGPDGVAKTPEWASQITGVPADKIIKLAREIGSTKPAFISQGWGPQRHA
                     NGEIATRAISMLAILTGNVGINGGNSGAREGSYSLPFVRMPTLENPIQTSISMFMWTD
                     AIERGPEMTALRDGVRGKDKLDVPIKMIWNYAGNCLINQHSEINRTHEILQDDKKCEL
                     IVVIDCHMTSSAKYADILLPDCTASEQMDFALDASCGNMSYVIFNDQVIKPRFECKTI
                     YEMTSELAKRLGVEQQFTEGRTQEEWMRHLYAQSREAIPELPTFEEFRKQGIFKKRDP
                     QGHHVAYKAFREDPQANPLTTPSGKIEIYSQALVDIAATWELSEGDVIDPLPIYTPGF
                     ESYQDPLNKQYPLQLTGFHYKSRVHSTYGNVDVLKAACRQEMWINPLDAQKRGINNGD
                     KVRIFNDRGEVHIEAKVTPRMMPGVVALGEGAWYDPDTKRVDKGGCINVLTTQRPSPL
                     AKGNPSHTNLVQVEKV"
     gene            39291..39908
                     /gene="dmsB"
                     /locus_tag="IRB70_001537"
     CDS             39291..39908
                     /gene="dmsB"
                     /locus_tag="IRB70_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethylsulfoxide reductase subunit B"
                     /protein_id="HBC0631462.1"
                     /translation="MTTQYGFFIDSSRCTGCKTCELACKDYKDLTPEVSFRRIYEYAG
                     GDWQEDNGVWHQNVFAYYLSISCNHCEDPACTKVCPSGAMHKREDGFVVVDEDVCIGC
                     RYCHMACPYGAPQYNETKGHMTKCDGCYDRVAEGKKPICVESCPLRALDFGPIDELRK
                     KHGDLAAVAPLPRAHFTKPNIVIKPNANSRPTGDTTGYLANPKEV"
     gene            39910..40773
                     /gene="dmsC"
                     /locus_tag="IRB70_001538"
     CDS             39910..40773
                     /gene="dmsC"
                     /locus_tag="IRB70_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dimethyl sulfoxide reductase anchor subunit
                     DmsC"
                     /protein_id="HBC0631463.1"
                     /translation="MGSGWHEWPLMIFTVFGQCVAGGFIVLALALLKGDLRAEAQQRV
                     IACMFGLWVLMGIGFIASMLHLGSPMRAFNSLNRVGASALSNEIASGSIFFAVGGIGW
                     LLAMLKKLSPALRTLWLVVTMVLGVIFVWMMVRVYNSIDTVPTWYSIWTPMGFFLTMF
                     MGGPLLGYLLLSLAGVDGWAMRLLPAISVLALVVSGVMSVMQGAELATIHSSVQQAAA
                     LVPDYGALMSWRIVLLAVALCLWIAPQLKGYQPAVPLLSVSFILLLAGELIGRGVFYG
                     LHMTVGMAVAS"
     gene            complement(40808..41434)
                     /locus_tag="IRB70_001539"
     CDS             complement(40808..41434)
                     /locus_tag="IRB70_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBC0631464.1"
                     /translation="MTKPYVRLDKNDAAVLLVDHQAGLLSLVRDIEPDKFKNNVLALG
                     DLAKYFNLPTILTTSFETGPNGPLVPELKAQFPDAPYIARPGNINAWDNEDFVKAVKA
                     TGKKQLIIAGVVTEVCVAFPALSAIEEGFDVFVVTDASGTFNEITRHSAWDRMSQAGA
                     QLMTWFGVACELHRDWRNDIEGLATLFSNHIPDYRNLMTSYDTLTKQK"
     gene            41749..42897
                     /locus_tag="IRB70_001540"
     CDS             41749..42897
                     /locus_tag="IRB70_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0631465.1"
                     /translation="MSTYTRPVMLLLSGLLLLTLAIAVLNTLVPLWLAQEHMSTWQVG
                     VVSSSYFTGNLVGTLLTGYVIKRIGFNRSYYLASFIFAAGCAGLGLMIGFWSWLAWRF
                     VAGVGCAMIWVVVESALMCSGTSRNRGRLLAAYMMVYYVGTFLGQLLVSKVSTELMSV
                     LPWVTGLTLAGILPLLFTRVLNQQTENHDSTSITSMLKLRQARLGVNGCIISGIVLGS
                     LYGLMPLYLNHKGVSNASIGFWMAVLVSAGILGQWPIGRLADKFGRLLVLRVQVFVVI
                     LGSIAMLSQAAMAPALFILGAAGFTLYPVAMAWACEKVEHHQLVAMNQALLLSYTVGS
                     LLGPSFTAMLMQNFSDNLLFIMIASVSFIYLLMLLRNAGHTPKPVAHV"
     gene            43107..44537
                     /locus_tag="IRB70_001541"
     CDS             43107..44537
                     /locus_tag="IRB70_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415419.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBC0631466.1"
                     /translation="MAGNVQEKQLRWYNIALMSFITVWGFGNVVNNYANQGLVVVFSW
                     VFIFALYFTPYALIVGQLGSTFKDGKGGVSTWIKHTMGPGLAYLAAWTYWVVHIPYLA
                     QKPQAILIALGWAMKGDGSLIKEYSVVALQGLTLVLFIFFMWVASRGMKSLKIVGSVA
                     GIAMFVMSLLYVAMAVTAPAITEVHIATTNITWETFIPHIDFTYITTISMLVFAVGGA
                     EKISPYVNQTRNPGKEFPKGMLCLAVMVAVCAILGSLAMGMMFDSRNIPDDLMTNGQY
                     YAFQKLGEYYNMGNTLMVIYAIANTLGQVAALVFSIDAPLKVLLGDADSKYIPASLCR
                     TNASGTPVNGYFLTLVLVAILIMLPTLGIGDMNNLYKWLLNLNSVVMPLRYLWVFVAF
                     IAVIRLAQKYKPEYVFIRNKSLAMTVGIWCFAFTAFACLTGIFPKMEAFTAEWTFQLA
                     LNVATPFVLVGLGLIFPLLARKANSK"
     gene            complement(44538..45446)
                     /locus_tag="IRB70_001542"
     CDS             complement(44538..45446)
                     /locus_tag="IRB70_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0631467.1"
                     /translation="MRMNMSDFATFFAVARNQSFRAAGDELGLSSSAISHSIKTLEQR
                     LKIRLFNRTTRSVSLTEAGSNLYERLRPAFDEIQIMLDEMNDFRLTPTGTLKINAARV
                     AARIFLMPLLVGFTREYPDIKVELTTDDSLVDIVQQGFDAGVRLSGIVEKDMISVAIG
                     PPVKLCVAATPEYFARYGKPRHPHDLLNHQCVVFRYPSGKPFHWQFAKELEIAVAGNI
                     ILDDVDAELDAVLMGAGIGYLLYEQIKEYLDTGRLECVLEDWITERPGFQIYYPNRQY
                     MSCGLRAFLDYVKTGQICQSQRHRPQ"
     gene            45546..46136
                     /locus_tag="IRB70_001543"
     CDS             45546..46136
                     /locus_tag="IRB70_001543"
                     /EC_number="1.6.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H oxidoreductase"
                     /protein_id="HBC0631468.1"
                     /translation="MQSERIYLVWAHPRHDSLTAHIADAIHQRAMERKIQVTELDLYR
                     RNFNPVMTPEDEPDWKNMDKRYSPEVHQLYSELLEHDTLVVVFPLWWYSFPAMLKGYI
                     DRVWNNGLAYGEGHKLPFNKVRWVALVGGDKESFVQMGWGKNISDYLKNMCSYLGIED
                     ADVTFLCNTVVFDGEELHASYYQSLLSQVRDMVDAL"
     gene            complement(46218..46958)
                     /gene="pflA"
                     /locus_tag="IRB70_001544"
     CDS             complement(46218..46958)
                     /gene="pflA"
                     /locus_tag="IRB70_001544"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase 1-activating protein"
                     /protein_id="HBC0631469.1"
                     /translation="MSVIGRIHSFESCGTVDGPGIRFITFFQGCLMRCLYCHNRDTWD
                     THGGKEVTVEDLMKEVVTYRHFMNASGGGVTASGGEAILQAEFVRDWFRACKKEGIHT
                     CLDTNGFVRRYDPVIDELLEVTDLVMLDLKQMNDEIHQNLVGVSNHRTLEFAKYLANK
                     NVKVWIRYVVVPGWSDDDDSAHRLGEFTRDMGNVEKIELLPYHELGKHKWVAMGEEYK
                     LDGVKPPKKETMERVKGILEQYGHKVMF"
     gene            complement(47150..49432)
                     /gene="pflB"
                     /locus_tag="IRB70_001545"
     CDS             complement(47150..49432)
                     /gene="pflB"
                     /locus_tag="IRB70_001545"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBC0631470.1"
                     /translation="MSELNEKLATAWEGFTKGDWQNEVNVRDFIQKNYTPYEGDESFL
                     AGATEATTTLWDKVMEGVKLENRTHAPVDFDTAVASTITSHDAGYINKQLEKIVGLQT
                     EAPLKRALIPFGGIKMIEGSCKAYNRELDPMIKKIFTEYRKTHNQGVFDVYTPDILRC
                     RKSGVLTGLPDAYGRGRIIGDYRRVALYGIDYLMKDKLAQFTSLQADLENGVNLEQTI
                     RLREEIAEQHRALGQMKEMAAKYGYDISGPATNAQEAIQWTYFGYLAAVKSQNGAAMS
                     FGRTSTFLDVYIERDLKAGKITEQEAQEMVDHLVMKLRMVRFLRTPEYDELFSGDPIW
                     ATESIGGMGLDGRTLVTKNSFRFLNTLYTMGPSPEPNMTILWSEKLPLNFKKFAAKVS
                     IDTSSLQYENDDLMRPDFNNDDYAIACCVSPMIVGKQMQFFGARANLAKTMLYAINGG
                     VDEKLKMQVGPKSEPIKGDLLNYDEVMERMDHFMDWLAKQYITALNIIHYMHDKYSYE
                     ASLMALHDRDVIRTMACGIAGLSVAADSLSAIKYAKVKPIRDEDGLAIDFEIEGEYPQ
                     FGNNDPRVDDLAVDLVERFMKKIQKLHTYRDAIPTQSVLTITSNVVYGKKTGNTPDGR
                     RAGAPFGPGANPMHGRDQKGAVASLTSVAKLPFAYAKDGISYTFSIVPNALGKDDEVR
                     KTNLAGLMDGYFHHEASIEGGQHLNVNVMNREMLLDAMENPEKYPQLTIRVSGYAVRF
                     NSLTKEQQQDVITRTFTQSM"
     gene            complement(49487..50344)
                     /gene="focA"
                     /locus_tag="IRB70_001546"
     CDS             complement(49487..50344)
                     /gene="focA"
                     /locus_tag="IRB70_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate transporter FocA"
                     /protein_id="HBC0631471.1"
                     /translation="MKADNPFDLLLPAAMAKVAEEAGVYKATKHPLKTFYLAITAGVF
                     ISIAFVFYITATTGTGTMPFGMAKLVGGICFSLGLILCVVCGADLFTSTVLIVVAKAS
                     GRITWGQLAKNWLNVYFGNLVGALLFVLLMWLSGEYMTANGQWGLNVLQTADHKVHHT
                     FIEAVCLGILANLMVCLAVWMSYSGRSLMDKAFIMVLPVAMFVASGFEHSIANMFMIP
                     MGIVIRDFASPEFWTAVGSAPENFSHLTVMNFITDNLIPVTIGNIIGGGLLVGLTYWV
                     IYLRENDHH"
BASE COUNT        12447 a        12567 c        13355 g        12088 t
ORIGIN      
        1 cgcttatatt aatgacaaaa gcattgagat cttattactt tcttgttttg cggcggctga
       61 ccaaaaagca atccagaggt atatacctca ggcgcaagat ggggaagact ttaggaatca
      121 tttacaatat aagttgactc ttcccactca ttaatgttgc tggtactaca taatacgaca
      181 ggtaagcggt gctccataat aaaaccaata tccggttacg aaacagataa ttgtacaggc
      241 ttatgtacct gtttttgaca caatgagatg atttcctaaa ctgatcaaaa ccttcttccc
      301 aacatggcat atcagtccga taatgcttta gagatcgaag gcttaacaaa caaggagatc
      361 gatcatgcaa ttttctacaa ccccaactct ggaaggccag accatcgtcg aatattgcgg
      421 tgtggtgacc ggcgaagcga ttttaggtgc caatattttc cgtgatttct ttgctggtat
      481 ccgcgatatc gttggcggac gctccggggc ttatgaaaaa gaattgcgta aagcgcggga
      541 gatcgccttt gaggagctcg gcgatcaggc ccgggcgctg ggggccgatg ccgtagtcgg
      601 tattgatatc gactatgaaa cggtcgggca aaacggcagt atgctgatgg ttagcgtcag
      661 cggtacggcg gtgaaaacgc gtcgatgaga agagtcttct ggctggtcgc cgccgctctg
      721 ttactggcag ggtgtgccgg cgaaaagggc attgtcgaga aagagggata tcagcttgat
      781 acccgacgcc aggcgcaggc ggcgtatccg cgcattaaag tgctggtgat ccactacacc
      841 gcagatgatt ttgatagctc gctggcgaca ctgaccgata agcaggtcag ctcgcattat
      901 ctggtccctg cggtaccacc gcgatacaac ggtaaaccgc gcatctggca actggtgccg
      961 gaacaggaac tggcctggca tgcggggatt agcgcctggc gcggggcaac gcgccttaac
     1021 gacacctcta ttggcattga gctggaaaac cgtggctggc agaaatcagc cggagtgaaa
     1081 tattttgccc cgtttgaacc ggcacagatt caggcgctta ttccactggc gaaagatatt
     1141 attgcccgtt atcacatcaa gccggaaaac gtagtggcac atgcggatat cgccccgcag
     1201 cgcaaagacg atccggggcc attatttccc tggcagcaac tggcgcagca ggggattggt
     1261 gcctggccgg atgcgcagcg ggtgaacttt taccttgccg ggcgcgcgcc gcacacaccg
     1321 gtagataccg cgtcattgct ggagcttttg gcgcgctacg gttatgacgt taaacctgat
     1381 atgacaccgc gcgagcagcg gcgcgtgatt atggcgttcc agatgcattt ccgcccgacg
     1441 ttatacaacg gcgaagcgga tgcagaaact caggcgattg ccgaagcgtt gctggagaaa
     1501 tacgggcagg attagcgcgg cagttttccg tggtcgcgta gccaggcggc agttttctcg
     1561 ataccttcat ccagggtgag gactggttga taacctaact cttcctgcgc acgcgtaata
     1621 tctagcgtaa agtcaaaatt caacttggag acgccgtagt gggtcagcgg cggctctttt
     1681 gctgacttgc ggcctaaacg ctccatgctg cgggcgatca tatccagcat cgggtagggg
     1741 acggaacgaa tacgacagtc aatattcaat tcgtcgatca gcttctgcac gatgctgcgc
     1801 agtgtgcgat gttcgccgtt ggtgatgttg tacacacgcc cggaaggtag cttatcgcag
     1861 gcttcctggc ttgccagcca catggcgtgc acggcatttt catagtaggt catatccacc
     1921 agcgcactgc cgccgtgcgg taacagaatg ctgccatagt ggtgcatcat atgcgccaga
     1981 cggggaataa agactttatc gtgcggtccg aacagacttt gtgggcgcag aatagtaaag
     2041 cgcgtttgtg gattcgcctg cgaaagcata ttgatcacct cttcgctggc tgctttgctg
     2101 cgggcaaact cgttggcgaa gcggtgaggg cgaaaatctt ctttaatatc gcgatggtgg
     2161 tgataatcga agtacaggga gggggaagag atatgaataa agttacgcac accccaggcg
     2221 acagcccatt cacccaggcg gcgagtggcg cgaacgttag ccagatcgaa agcctgttgt
     2281 gtcccccagg gcgaggtaaa gctggagcag tgccacagcg tatcaatgcc cgcgagcatc
     2341 actttagctt gtgatgagac cagctcggtc agatccgccg gaacaaactc tgcgcccatt
     2401 ttttccagca atttacccat tgcctcgttg cgaccggtcg ctcgcacgct gatgcctttc
     2461 tggcataaaa actctaccgc gtttcgacct aagccgctgg tggcgccggt aaccagtacc
     2521 ttcatatcaa tccactgttg ttgagaaaat gacgtgcgca ttcttccgtg atttccccca
     2581 tgatgcaatg ggaaacatga aagaataacg caggttttgt cgattaatct gtgctttgtt
     2641 ctgccagtct ggcgatttgt tttgccattc cgcgaaaaat aaacagatgc gcggggatca
     2701 tcaataacca gtaaaacagc cccggcatac cgtgcggatg ccagaatgcg cgaacatcga
     2761 tagtacgata gtcgccttta tcttccaggg taaaacacag tcgtcccagc cccggcgctt
     2821 tcatgccaaa taacagcgta agttgttttt ccggttcaac gacaatcact ttccagctat
     2881 ccaccgcatc gccggtctgc aaatattcac gctccgggcg gcctttcgcc agcttatgac
     2941 cgatcgcgcg gtccatcaac gcccgggttt gccacaaaat gttgccaaag aaataacgct
     3001 ctttaccgcc gatttgattc accacctgcc ataaagccgc aagactggcg gacgttttaa
     3061 cggtaaaccc cgcctgtttg gcgaaataac cgtactccgg tcgccagcgg gcaaaggcct
     3121 gagcgtcgta gccccagtcg ctggagttga ccagcttttc ttcttctttc agggtgcgac
     3181 gtaccgcgtc atcgaaagca atcagccgtt gtgggatgag tgcacgtaac gcggtgtcat
     3241 ctgccagcag atcgtgtttc agcccctgaa tcaacgcttt ggcggtggtg ggcggtacgg
     3301 aagtaatcac attgagaaac cacaccgaaa tccagcgggt cggaaagggg atggggatca
     3361 accagcggcg cttaccgctc accgccataa aatgttcaaa ctgttgctga taactgagca
     3421 cttctggtcc ggcggcttcg aagatgcgat gttcgctggc cggatgatct aacagcgcca
     3481 ccagatagtg cagcaagttt tccagcgcga tgggcgtggt gcgtgaacga acccagcgtg
     3541 gcggcgttaa cactggcagg ttgtagacca tatcgcgcat gacttcgaac gccgctgaac
     3601 ctgcaccaac gattattccg gcacgcaatt cggtcaccgg gacacccgct tcacgaagaa
     3661 tatccgccgt agcctgacgg gcgcgcagat ggtcagactg ctcatgtgcc ggggcctgca
     3721 acgaactgag aaagattaat tgcttaactg ggacttcacg tagcgcatcg cggacgttga
     3781 gagccacctg gcgctcctga gcgataaaat cgccgccttc gcccatgctg tgcaccagaa
     3841 aatagaccgt atcgatatcc tgcaacaggg ccggaaggtt atccggccag ctgagatcga
     3901 ctttatggca actgacgttt gccagttgca gctttgcaag cctgtcgaca tgacgtgccg
     3961 ccgccaggat ctgatgccct tgctggctga gtgtgtgcac cagatgctga ccaatatagc
     4021 cactggcacc gagaactaaa atgcgttgcg gcacgtctcc ctccttaacg cgccaggaat
     4081 gcgcgccagt gggcggcgac ttccgccagc tgagcgcgcg agacgtcaag atgcgtcacc
     4141 aggcggacaa tcggcgaggc gttaatcagc acgtttctcg ctttcatgta ttcgcctaac
     4201 gcggcagcat tttcttcccc gacgcgaaca aacagcatat tggtgtcctg acgcatcaca
     4261 tccgcgcctg cttcacgcag ctgctccgcc atccaggcag cgttgtcgtg gtcttcctgc
     4321 aagcgcgcaa cgttattttt cagggcatat attccggcgg cagccagaat gccggactgg
     4381 cgcatcccac cgccggtcat tttccgccag cgaatggcac gtttaatgta atcacgatta
     4441 ccgacgagta atgaaccgac tggcgtccca agacctttcg acaggcaaat ggtgaacgaa
     4501 tcacaatatt gtgtgatctc tttcagttcg cagccgtaag ccaccacagc attaaagatg
     4561 cgcgcaccgt ccacatgcag cgccagattg cgctcgcggg taaattccca tgcttctttg
     4621 aggtattcac gcggcagcac tttgccgttg tgagtgtttt ccagactgag taatttggtg
     4681 cgggcgaaat ggatatcgtc gggtttgatt ttcatcgcca ctttatccag cggtagcgtg
     4741 ccgtcggcag ccgcgtcgat gggttgcggt tgaatactgc ccagcaccgc cgcgccaccg
     4801 gcttcaaaca gatagttatg cgcggcctga ccgacaatat actcttcgcc gcgttcacag
     4861 tgactgagca gagcgaccag gttggcctga gtgccggtag gcagaaaaat ggcggcttct
     4921 ttaccggaaa gctctgctgc atagtcctgc agagcattaa cggtagggtc gtctccgtaa
     4981 acgtcgtccc caaccggggc ggccatcatc gcttcgagca tggcgcggct cggtcgggta
     5041 acggtatcac tgcgtaaatc aatcatggca tgtccttatt atgacgggaa atgccaccct
     5101 ttttacctta gccagttcgt tttcgccagt tcgatcactt catcaccgcg tccgctgatg
     5161 attgcgcgca acatatacaa gctaaatcct ttggcctgtt caagtttgat ctgcggtgga
     5221 atggctaact cttctttggc tactaccaca tccaccaaca ccggaccgtc gatggaaaag
     5281 gcgcgttgca gggcttcatc gacttcagag gctttttcca cgcgaatacc cgtaattccg
     5341 cacgcttcgg caatgcgggc aaagttggtg tcgtgcagct cagtaccgtc tgtcaggtag
     5401 cctccggctt tcatctccat cgccacaaag cccagcacgc tgttattaaa gacgataatt
     5461 ttcactggca atttcatctg cattactgag aggaaatcgc ccatcaacat actgaaaccg
     5521 ccatcgccgc acatggcgac cacctgacgt tccggctcgg ttgcctgcgc acccagcgcc
     5581 tgcggcatgg cgttagccat cgaaccgtgg ttaaacgaac ctaacagacg acgcttgccg
     5641 ttcattttca gataacgcgc tgcccatact gtcggcgtac caacgtcaca ggtgaaaata
     5701 gcgtcatcgg cggcaaaatg actaatttgc tgcgccagat attgcgggtg aatggctttc
     5761 tcgctcggtt tagctaaatc gtccagccct ttgcgggcat cgcggtaatc ttccagcgct
     5821 ttatccagaa acttgcgatc ggttttttct tccaccaatg gcagcaatgc acgcagagtc
     5881 gacttgatat cgccgaccag tgccatatct accttgctgt gcgcaccaat gctagctgga
     5941 ttaatatcaa tctgaataat ttttgcatcg gtcgggtaga aagcacggta gggaaattgc
     6001 gtgccgagca gcactaacgt gtcggcgttc atcatggtat ggaaacctga cgagaagccg
     6061 attaatcccg tcattccgac atcatacgga ttatcgtatt cgacatgttc tttaccgcgc
     6121 agggcatgaa caataggcgc tttaattttc ccggcaaact caactaactc tttatgcgcc
     6181 cccgcgcagc cgctgccaca catcagggcg atattgctgg aataacgcag cagttgcgcc
     6241 agtttgcgta actcttcttc ttccggcgtc acgactggtt gtggcgcatg ataccagtgc
     6301 gtggttgccc cttctggcgc aggttttaac gccacgtcgc ccggtaacac gacaacggaa
     6361 acgccacggt ttagcaccgc tttgcgcatg gcaatcgcca gcacttgtgg gatttgctcc
     6421 gggctggaaa ccagctcgca atagtgacta cattcgcgga ataactcttg tgggtgggtt
     6481 tcctggaaat agccgctgcc aatttcgctg gagggaatat gagcggcaat cgccagtacc
     6541 ggaacgtgat tgcggtggca atcgaacagg ccgttgatta agtgcaggtt accgggaccg
     6601 cacgatccgg cacagaccgc cagttctccg ctaagttgtg cttcagcgcc agcggcaaac
     6661 gccgccactt cttcatgccg ggtggacatc cactcgatgg tgcccatgcg attaagactg
     6721 tcactaagac cgttcagaga gtcgcccgtg actccccaga tgcgtttcac tcctgccgat
     6781 tcgagtgttt tggcgatata agctgcaacc gtttgtttca tggttctcca tctcctgaat
     6841 gtgataacgg taacaagttt agttcatctg acggaggggg aagggatggg agaaaaagga
     6901 ggcactaacg gttaaatagc ccgatgaaag gaatatcatc gggcataagg cgattatgcg
     6961 agaaccaaat ccccctgcgg atggcaggag caggccagta cgtaaccttc agcgatttcg
     7021 gcgtcggtca gcgtcattgt gctgctcacc gtatattcac cggaaaccac tttcgtctta
     7081 cagcagccgc aaacacctgc gcggcaggcg gcgacaaccg gaacgttatt gctttccagc
     7141 gcctccagta gcgtggtgcc aaccggggcg taaaattctc gtgccggttg cagtttggtg
     7201 aatttcagac cgctggtcgc cgcttccgct actggggtga agaatttctc tttaaagaaa
     7261 cgcgtcacgc cgagcgcttt cacttcctgc tctacccaat ccatatatgg agcagggcca
     7321 caggtcatca cggtacgtga ggctaaatca gggacacctg ccagcagttc gcgagtgaga
     7381 cgaccagcga taaagccttc ggtaacgtta ttttccgcca ccagcgttac cggatagtta
     7441 cgccactcat cggcgaaaat cacatcctgc ggcgtacgca cgttgtagat cacctgcaca
     7501 tcggcctgtg gacggttctt cgccagccag cgacgcatcg acataatcgg cgtaacgccg
     7561 cagcctgccg ccagcaacag gaatttatct tctgctttat cgtcgcaggt aaattccccc
     7621 atcgcgtccg aaagccagag ataatcaccg cgttttacat cgcgcgtcag ccaccgggag
     7681 ccgacaccgt catcaatccg ccgcacagtc agggtgatgt attcactcac gcctggcgtg
     7741 gaggaaatgg tgtaagcacg cagcgtttcc gctgagttac gcacgctgac cagtgcatat
     7801 tgcccggcgc gatatgggta gtaatcgtgg caaatcaggg aaatcgtcca cacatccggc
     7861 gtttcttgcg taatgtgatg aacctgcatc cgccacgggc attgattcgt tggcatcgtc
     7921 atcgacaaac tccttacgcg ctcaacagtt gcttcatgtc ttcttcaaca gtggtgatag
     7981 aacgcaggcc gaatttctcg ttcagcaccg ccagcaggtc tggtgtcagg aaaccaggtg
     8041 cagtcgggcc ggtgacgata tttttcacac ccagagaaag cagcgtcagc agaatgacaa
     8101 tcgctttctg ttcaaaccag gagagcacca gcgacagcgg cagatcgttg actccgcagc
     8161 ccagtttctc tgccagcgtt accgccagaa taattgctga gtaagcatcg ttacactgac
     8221 cagcatctac cagacgcggc agaccttcga tatcgccaaa ctcaagttta ttaaagcgat
     8281 atttaccgca agcgagggtc aggatcaggc agtcatccgg cacgctggtg gcgaaatcgg
     8341 tgaagtagtg acgctcgccg cgtgcgccgt cacagccgcc aagcaggaag atatgacgca
     8401 gtttttcacg gctcaccaga tcaatcagcg tatcggctgc gccaagcagt gtctggcgac
     8461 caaagcccac ggtgatcagg tgcggaattt cgctgtacgg gaagcccgcc atctgttgcg
     8521 cctgggcgat gaccgcagag aaatcttcgc catccagatg acgcacaccc ggccagccaa
     8581 cgatgctgcg ggtccagata cgatcgtcat aagcgcctac ggttgggtcg atgatgcagt
     8641 tcgaggtcat cacgatgggg ccagggaaac gagcgaactc cacttgctga ttctgccagc
     8701 cgctgccgta gttaccgacc agatgcttga atttacgcag ctccgggtag ccatgcgcag
     8761 gcagcatttc accgtgggtg tagacattaa cgcccgtgcc ttcggtctgt tccagcaggt
     8821 tgtagagatc tttgagatcg tgaccggaaa tcagaatgca tttacctgcc gtcgctttga
     8881 cgttgacctg ggttggcgtc gggtgaccgt atttactggt ttcgcctgca tccagaatgc
     8941 tcatcacttt gaagttcatc tggccgattt ccattgaaca ctcaagaagc gcgttcatat
     9001 cggcaggcca ggtccccagc cacgccatga ttttatggta ctgggcataa atatcgttgt
     9061 cgtattgacc gagaacatgc gcgtgttcca tataggccgc cgcacctttc aggccataca
     9121 ggcacagcag acgcaggccg agaatgtttt cgccaatcgc cgctttatct ttgttagggg
     9181 taaattctgc tgcctgacgt tgcagctcgc cgagatcgtc gctcaccagt tgcaggtcag
     9241 ccatcgggtt atcgacgtgc gcgttggcat ctacagccag gcattgtgct ttcagcgcct
     9301 cgcgcaggac aatcgcttca cgagcgtagc cgacaattcg cggagaatcg aagttaacgt
     9361 tggtcagggt tgagaaaaag gcacgtggcg caaagctgtc tacatcgtgg ttgatgatgc
     9421 cgtattcacg tgctttcact gcccaggccg aaagcccttg cagcgtcgcg atgagtaaat
     9481 cctgaaggtc agaggtttcc gccgttttac cacacatccc ctgcgcgtat gagcagccgt
     9541 ttcctgccgg agtacggata gtttgttcac attgcacaca aaacatgatc acacctttaa
     9601 agttatattt aatatgcatg tttaaggtta agacgcttaa cgcggggata aaagggattt
     9661 ttcatgcaac tttaagggag attgatttag cgcaattttg gcggcaggga tctaccgcca
     9721 gagaggtatt atgcagagaa aaaggcgatg agaatcggca ctaacagact aagaataaaa
     9781 ccgtgaacaa tcgccgccgg gaccatatcc agcccgccag tacgttgaag aacgggcagg
     9841 gtgaaatcca tcgatgtggc accgcataag cccagtgcag tagagcggct gcggcgaatc
     9901 agcccaggga tcaacataat agcaatcagc tcacgggcca gatcattaaa aaacgccgcg
     9961 ctcccgatta ccggaccaaa agattcggtc aataaaatac cggaaagaga ataccagccg
    10021 aaaccggagg ccattgccag cgcggtattg atgggaagat caagaataaa ggcgttaatt
    10081 aaaccaccaa ttaatgaact ggcaaccacc accacggcga caatcattcc ccggcgatta
    10141 aggacaatct gctttaaggt catgccatta ttgcgcaact gaataccgac gaggaaaagt
    10201 agcagaatta aggtgtattc actggcttcg gtcgcgtgtt gtaagaaagc cagtccactc
    10261 aggccaatgg caaaaccaat cactactacg ccgcacagtt ttagcgactc cagcgccatc
    10321 gcaatacgcg atgggagttt ttcttgctgg tggtagttgc gccacggcag accgcgctcc
    10381 agccacatca gggcggcaat attacacagt aaaataacgg taatactgac agcagaataa
    10441 tgcagaatcg ccaacaggtt actggcgagg ttatcgagaa acgccagact gatacccata
    10501 aaaaagagaa tgaggtaaac catccaactt aatagctgat taataacttt taatgcagct
    10561 ttttggcgaa gcggaatgag gtaacccaaa atcaggggaa ccagaatgat taacagccca
    10621 gaaaacatga aaacccagtc cttgcaaaga tgaagtcgaa atgcgcgatg acacactact
    10681 gaaagcggaa ggacgagtaa agttgcaatt aaaaggaaat gttatgcatc agagggggat
    10741 ttttaattct atattagtgt ttagcattgt tgcgctcctt tcatgtgcaa tgccatataa
    10801 agccactggc gcagggagcg cgcagggggc ggccagtcgc cgccgccccc tgcacccccg
    10861 ggctctggcg aacaaaatcg ccgctgcgcg gtaccttcag cttatcccct tcggctaccg
    10921 ggtcgggcgc gaggtaacgt ccctgtaaga cgcgccctca gcccacatcc atgtgggctg
    10981 ccccggcctt cggggaacgc ttcagcgatt ttgacgccac caacacccgt gcggtttgta
    11041 acgtcgaaga taaaacaacc agggcagata aaatgccaat gctaattaat tacgtttttc
    11101 cagtagagtc cggtaaatca gaccaccgat aataccgccg acaattggca ccacccagaa
    11161 gaaccacaat tgttctaacg cccagccgcc ctggaagata gcaaccgcgg tgctgcgcgc
    11221 cgggttaaca gaagtgttag tcaccggaat actgattaag tgaatcaggg ttaaggccag
    11281 accaatagcg atcggcgcaa aacctgccgg agcgaatttg tcggttgcgc cgtggatcac
    11341 cagcaggaaa cctgcactca ataccagttc aactaccagc gcggaaagca tggaataacc
    11401 gcctggcgaa tgctcgccat aaccgttaga agcaaaaccg ctggctgccg cgtcaaaacc
    11461 tgttttacca ctggcaatta aatacagcag cgccgccgca acaataccgc cgacaacctg
    11521 ggcaattacg tagccaacga cttcttttgc cggaaaacgt ccgccagccc ataaaccaat
    11581 agtgaccgcc gggttaaaat gaccaccaga aatatgacca acagcgaagg ccatcgtcag
    11641 aacggtcaga ccgaatgcca gcgccacgcc ggcaaaacca atgcctaatt ccgggaagcc
    11701 tgcggccagt acggcactac cacagccacc aaaaacaagc cagaaagtac caaaacattc
    11761 agctgctaat tttctgaaca tatccacctc aattaaaaat tgaccctgtg aaaaatatgg
    11821 tcgttttata gggtcgtcgt aaaaaagtga cgacggaaat aatgcgcggc tattttaaaa
    11881 acgaaggcga gtcattcacc agataaataa atccagtaaa tttgatttag ggcaacagcg
    11941 ggttgcccca tatagtcatt tgtctgattg acagtgtagt gcaagcaaaa gatttaatcc
    12001 tttaggcgta ataaaaaata atttatcatg ctaattattt gattttgttg tttttgcagg
    12061 cttatcagca agagggagta taacgcgatt attcgctcat ttttcagaca tttgccatgc
    12121 ttaaatgtga tgtcatcacg tattagcaag gcctttcccg ttatactgcc agcgtaaagg
    12181 ataagtcaca tatttctgga ggggatatga ttcttgagcg cgttgaaatt gtgggttttc
    12241 gcggtatcaa ccgtttgtcg ttgatgctgg aacaaaacaa cgtcctgatt ggggagaacg
    12301 cgtggggtaa atccagcttg ctggacgcct taaccctgct gctatcgcca gaatcagatc
    12361 tctaccattt tgagcgcgac gatttctggt tcccgccggg agatatcaac gggcgagaac
    12421 atcatctgca tattattttg accttccgcg aatcgctgcc aggccgacat cgggttcgcc
    12481 gctatcgacc gctggaagcg tgctggacgc catgcaccga tggctatcac cgtatttttt
    12541 atcgtctgga aggggagagt gcggaagacg gcagcgtgat gacactccgc agttttctcg
    12601 ataaagacgg acatccgatt gatgtcgagg atattaacga tcaggcacgc catctggtgc
    12661 gtttaatgcc ggtgctgcgc ttgcgtgatg cccgttttat gcgccgtatt cgtaacggca
    12721 cggtgccaaa tgtccctaat gtggaagtca ccgcgcgcca gctcgatttc ctcgcccgtg
    12781 agttatcctc acatccgcaa aatctctctg atgggcagat tcgtcaggga ctttccgcaa
    12841 tggtacagct gcttgagcat tatttctctg agcagggggc cggacaggcg cgatatcgtt
    12901 taatgcggcg gcgagccagc aatgagcaac gaagttggcg ctatctggat atcatcaacc
    12961 ggatgattga ccgacctgga gggcgctcgt atcgggttat tttgctcggc ctgtttgcta
    13021 ctttgttgca ggcaaaaggc acattgcgac tggataaaga cgcccgtcca ttgttgctga
    13081 tcgaagatcc agaaacccgt ttacacccca ttatgctttc agttgcctgg catctgttga
    13141 atcttctgcc attgcagcgc attgccacca ccaactctgg cgagctgctt tcgttaacgc
    13201 cggtagagca tgtttgccga ctggtacgtg agtcctcgcg cgttgccgcc tggcgtctgg
    13261 ggccgagtgg tttgagtacc gaagatagcc gacgcatatc ctttcacatt cgttttaacc
    13321 gtccgtcatc gctgtttgca cgctgctggc tgctggtgga aggggaaacg gaaacctggg
    13381 ttatcaatga actggcgcgt cagtgcggac atcattttga tgctgaaggg atcaaggtca
    13441 ttgagtttgc ccagtccggg ctaaagccac tggttaaatt tgcccggcga atggggattg
    13501 aatggcatgt actggtcgat ggcgatgaag cagggaagaa atatgccgct acggtacgca
    13561 gcctgttgaa taacgatcgg gaagccgaac gagaacattt aacggcgtta ccggcgctgg
    13621 atatggaaca ttttatgtat cgccagggat tttccgatgt gttccaccgc gtggcgcaaa
    13681 tcccggaaaa tgtaccgatg aatctgcgca aaattatctc gaaagcgatc catcgctctt
    13741 ccaaacccga tcttgccatt gaagtggcaa tggaggccgg acgtcgtggt gtggactccg
    13801 taccgacgct gctgaaaaaa atgttctcac gcgtgctgtg gctggcgcgc ggtcgcgcgg
    13861 attaaccgcg aaacatcgtg gccatttgtg gctgaatagc gtcgagcatc tcatagcgcc
    13921 gacggtattc agcccgtttt ttactggcga tttcggcaat ctcttttcgt gctatctgtg
    13981 ctggaaggcg gtaatggcgt tcagcatcac atacgccgcc aaccgactcc cagaacgcgt
    14041 tgtaatcggc atggatcttg ccttctttat cacgataacg caggctgcgg taaatatgcg
    14101 tttcattgct gacggcaata atctgctcta cctgcaaacg ttgggcaaac agacaggccg
    14161 cttccatcac gaggcgtttg ggaaatagcc cgtggcaggc tttcgtcgca ttctggattt
    14221 cctggtgtgg aatttcccat tttgcgcctt gcagtccgcc aataaacatc gtccttttcc
    14281 cctgatattc acacagggta aacgtgagct ctgccagagg aataccttcg ctgttgcgga
    14341 acaggatggt gctgtcacct tctttatcca ttgagatcat catggtcagc tcaagcgtga
    14401 actgctcgcc gtttttgcct tccagcttcg ccagttgcag cccgggggta ttcaaatata
    14461 agctgaattc ttccgccgac atacacccgc ggagtaacgc ataatggtaa cgtaacgcct
    14521 ccagcaattg cttacggcta agattcgccg caaggtaagg gcgatgtaga cgtacaggca
    14581 gtcgcggctg gcgcgttaac aacacattga gattaggcca gtgggaaagt tcgttcatcc
    14641 actcaacgct taaacgcggc ataatcaacg agcgcagcaa aaatttctgg cgaaaactac
    14701 ggcgatgcca gaatttaccc ggccgacact gtccacgtgc cagactaaga aaaagtgaca
    14761 ggctgctgag agattcagat ggcgtaaagg tccgttcagt tagctgcgac atattcatga
    14821 aatcaatgat tatacatgac gtcgatttca ccattgcgta tcttaaccaa acatcaatag
    14881 tgtgattact aacgtaaatt ttagggtttt gttgatattt cgttgaagtt aatgacccgg
    14941 attggcatat ggagtattca gaatatttat gaaaaagcgg aaaaccgtga agaagcgtta
    15001 cgttattgcg ctggtgatag tcatcgccgg actgattacg ttatggagaa ttcttaacgc
    15061 acccgttccg acttatcaga cgctgattgt gcgccccggt gatttacagc aaagcgtgct
    15121 ggcgaccgga aagctggacg cgctgcgtaa ggttgacgtg ggcgcgcagg tcagcggtca
    15181 gttgaaaacg ctgtcggtgg cgattggcga taaagtaaaa aaagaccagc ttttaggggt
    15241 tattgatcct gaacaggctg aaaaccagat caaggaggtg gaagcaacgc tgatggagct
    15301 acgcgcgcag cggcagcagg cggaagcgga gctgaaactg gcgcgggtga cgtattcccg
    15361 tcagcaacgt cttgcacaaa cgcaagcggt ttcacagcag gatctcgata ccgccgcgac
    15421 ggagatggct gtgaaacagg cgcaaattgg caccattgac gcgcaaatca agcgcaatca
    15481 ggcctcactc gatacggcta aaaccaatct cgattacacc cgcatcgttg ccccgatggc
    15541 cggggaagtc acgcaaatca ccactctgca aggccagacg gtgattgccg cacaacaagc
    15601 accgaacatt ctgacgctgg cagatatgag caccatgctg gtaaaagcgc aggtttctga
    15661 agcggatgta atccacctga agccggggca aaaagcctgg tttacggtgc ttggcgatcc
    15721 gctgacgcgc tatgaggggc aaatcaagga tgtgctaccg acgccggaaa aggttaacga
    15781 cgctattttc tattacgccc gttttgaagt ccccaacccc aatggtttgc tgcggctgga
    15841 tatgaccgcg caagtgcata ttcagctcac cgatgtgaaa aatgtgctga cgatccctct
    15901 gtcggcgtta ggcgatccgg ttggcgataa tcgttataaa gtcaaattgt tgcgtaatgg
    15961 tgaaacacgc gagcgtgaag tgacgattgg cgcacgtaac gataccgatg ttgagattgt
    16021 caaagggctg gaagctggcg atgaagtggt gattggtgag gccaaaccag gagctgcgca
    16081 atgacaccct tgctcgaatt aaaggatatt cgtcgcagct atcctgccgg tgatgagcag
    16141 gttgaggtgc tgaagggcat cagcctcgat atttatgccg gtgagatggt ggcgattgtc
    16201 ggcgcttcag gttccggtaa atcgaccctg atgaatattc tcggctgcct ggataaggcc
    16261 accagcggca cctatcgcgt cgccggtcag gatgttgcca cgctggacgc cgatgcgctg
    16321 gcgcaactac gccgcgagca tttcggcttt attttccagc gttaccattt gctttcgcat
    16381 ttaaccgccg agcagaacgt tgaagtaccc gccgtctatg ctggtcttga gcggaaacag
    16441 cggctgcttc gcgcccagga gttgctgcaa cgactggggc tggaagaccg tacagagtat
    16501 tatccggcac agctttcggg tggtcagcaa cagcgtgtca gcatcgcgcg ggcattgatg
    16561 aacggcggtc aggtaattct tgccgatgaa ccaaccggcg cactggacag ccattctggc
    16621 gaagaggtga tggcgatcct gcatcagctg cgcgatcgcg ggcatacggt gattatcgtt
    16681 acccacgatc cgcaggtcgc tgctcaggcc gagcgggtga tcgaaattcg cgacggcgaa
    16741 attgtgagca atcctcccgc cattgaaaaa gtgaatgttg ctggcgggac ggaacctgtt
    16801 gtcaacacgg cgtctggctg gcggcagttt gccagcggtt ttaacgaggc gctgacgatg
    16861 gcatggcggg cgctggcagc gaataaaatg cgtactttac tgaccatgct ggggattatt
    16921 atcggtattg cgtcggtggt ttcaattgtc gtggtgggcg acgccgccaa acaaatggtg
    16981 ctggcggata ttcgttctat tggtacgaat actattgatg tctatcccgg aaaagatttt
    17041 ggcgatgacg atccgcaata tcagcaggcg ctgaagtacg acgacttaat cgccatccaa
    17101 aaacaaccgt gggtcgcctc agccacacct gccgtctcgc aaaacctgcg cctgcgttat
    17161 aacaatgttg atgtggctgc cagtgccaat ggcgtgagcg gcgattattt taatgtctat
    17221 ggcatgacct tcagtgaagg gaacaccttt aatcaggagc agctgaacgg tcgtgcgcag
    17281 gtcgtagttc tcgacagtaa tactcgccgc cagcttttcc cccataaagc cgatgtggtt
    17341 ggcgaggtga ttctggtcgg caatatgccc gccagagtca ttggtgtggc ggaagaaaaa
    17401 cagtcgatgt ttggtagcag taaagtgctg cgtgtctggc taccttacag cacgatgtcc
    17461 gggcgagtta tgggccagtc gtggctcaac tccattactg tcagggtgaa agaaggattt
    17521 gacagcgccg aggcggaaca gcaactcacg cgtttacttt cactgcgcca cggtaagaag
    17581 gatttcttta cctggaacat ggacggcgtc ttgaaaaccg ttgaaaagac cacacgtact
    17641 ttacaactgt ttctgacgct ggtggcggtg atttcgctag tggtgggcgg tattggtgta
    17701 atgaatatta tgctggtgtc agtgaccgag cggacgcggg aaattggcat tcgcatggct
    17761 gtaggtgcgc gagcaagcga tgttttgcaa cagttcctga tcgaagccgt actggtttgc
    17821 ctggtcggtg gcgcgttggg aataacactg tcactgttaa ttgctttcac cttgcagctt
    17881 ttcttacctg gctgggagat tggtttttca ccgttggcgc tgctgctggc gtttctctgc
    17941 tcgacggtca ccgggatttt atttggctgg ttacccgcac gaaatgcggc acgactggat
    18001 ccagtagatg ctctggcacg agagtaattt ttgagataaa aatgccagcc gatcgggctg
    18061 gcattttgcc tttaggatgt acacaatgag acagaagagc tatgcgactg ccgcttctac
    18121 ttcgacgggc acaataacac tggcgtgatt gccttttggc ccctggtgga catcaaactg
    18181 aacggattgt ccagctttta gcgttctgta accatccatc tgaatggtgg aataatgagc
    18241 gaaaatatct tcgccgccgc cttcagggca gatgaaacca aaccctttgg cattgttgaa
    18301 ccacttaaca gtaccctttt ccatgcttcg acatccttcg caaatcttat acaagtaaga
    18361 tggaataaac cggggtcaga gagggggctg ttcaaaacct cgccaactct agaaatacaa
    18421 tttagagaat tagggcgagc cgtcaagcat ttgacagggg ccagggggca ggtatgaatc
    18481 aaaaatttga agcagttaac gctattgaca ggaatgtgac agatgtcgct gatgccaacg
    18541 atagatgata gttatctatc atgtggagta gattggtcag gcaaataagc tcttgtcagc
    18601 ggcagggcgt tctgccgata accgtaaccg aagatgataa ctgacaatgg gtaaaacgaa
    18661 cgactggctg gactttgatc aactggcgga agaaaaagtt cgcgacgcgc taaaaccgcc
    18721 atctatgtat aaagtgatat tagtcaatga tgattacact ccgatggagt ttgttattga
    18781 cgtgttacaa aaattctttt cttatgatgt agaacgtgca acgcaattga tgctcgctgt
    18841 tcactaccag gggaaggcca tttgcggagt ctttaccgcc gaggttgcag aaaccaaagt
    18901 ggcgatggtg aacaagtacg cgagggagaa tgagcatcca ttgctgtgta cgctagaaaa
    18961 agcctgaatg caggcataaa aattggggga ggtgcctatg ctcaatcaag aactggaact
    19021 cagtttaaat atggctttcg ccagagcgcg cgagcaccgt catgagttta tgaccgtcga
    19081 gcacttgtta ctggcgctgc tcagtaaccc atctgcccgg gaggcgctgg aagcgtgttc
    19141 tgtggatttg gttgcgctcc gtcaggaact ggaagccttt attgaacaaa ccacacccgt
    19201 tctgcctgcc agtgaagagg agcgcgacac acagccgacg ctgagttttc agcgtgtact
    19261 gcaacgtgcg gtcttccatg tccagtcctc cggtcgcaat gaggttaccg gtgcaaacgt
    19321 tctggtcgct atctttagcg aacaggagtc gcaggcggca tatctgttgc gtaaacatga
    19381 agtcagccgt ctcgatgtgg tgaactttat ctctcatggc acgcgtaaag acgagccgac
    19441 acagtcttct gatcctggca gccagccaaa cagcgaagaa caagctggtg gggaggaacg
    19501 tatggagaat ttcacgacga acctgaatca gcttgcgcgc gtgggcggaa tcgacccact
    19561 gattggtcgt gagaaggagc tggaacgtgc tattcaggtt ctctgccgtc gccgtaaaaa
    19621 caacccgctg ctggtggggg aatctggtgt cggtaaaacc gcgattgcgg aaggtcttgc
    19681 ctggcgaatt gttcagggcg atgtgccgga agtgatggct gactgtacga tttactctct
    19741 cgatatcggt tctctgttag cgggcacaaa atatcgcggc gactttgaaa aacgttttaa
    19801 agcgttgctc aagcagctgg agcaggacac taacagcatc ctgtttattg atgagatcca
    19861 caccattatc ggtgcggggg cagcgtctgg tggtcaggtt gatgcggcta acctaatcaa
    19921 accgttgctc tccagcggta aaattcgcgt aattggttcg acaacctatc aggagttcag
    19981 caacattttc gagaaagacc gtgctctggc gcgtcgcttc cagaaaattg atattactga
    20041 accttcgatc gaagaaactg ttcaaatcat caatggcctg aaaccgaagt acgaagcgca
    20101 ccatgacgtg cgttataccg caaaagcggt gcgtgcagcg gtagagctgg cggtgaaata
    20161 cattaacgat cgtcatctgc cggataaagc cattgacgtt atcgacgaag cgggcgctcg
    20221 cgcacgcctg atgccggtaa gcaaacgcaa gaaaaccgtt aatgtggcgg atattgagtc
    20281 tgtggtggcc cgtattgcgc gcattccaga gaagagtgtt tcgcagagtg accgcgatac
    20341 cctgaaaaac ctcggcgatc gcctgaaaat gctggtcttc ggtcaggata aagccattga
    20401 ggcgctgact gaagccatta agatggcgcg tgcaggttta ggtcacgaac ataaaccggt
    20461 cggttcgttc ctgtttgccg gtcctaccgg ggtcgggaaa acagaggtga cggtacagct
    20521 ttcgaaagct ttgggcattg agcttctgcg ctttgatatg tccgagtata tggaacgcca
    20581 taccgtcagc cgtctgattg gtgcgcctcc gggatacgtt ggttttgatc agggggggct
    20641 gctgaccgat gcggtaatca agcatccgca cgcggtactg ctgctggacg aaatcgagaa
    20701 agcgcatccg gacgtgttca atattctgtt gcaggtgatg gacaacggta cgctgaccga
    20761 taacaacgga cgcaaagcgg acttccgtaa cgtggtattg gtgatgacca ccaacgccgg
    20821 ggtacgagaa actgagcgta aatcgattgg tcttatccac caggataaca gcaccgatgc
    20881 gatggaagag atcaagaaga tctttacacc ggaattccgt aaccgtctcg acaacattat
    20941 ctggtttgat catctgtcaa ccgacgtgat ccatcaggtg gtggataaat tcatcgtcga
    21001 gttgcaggtt cagctggatc agaaaggtgt ttctctggaa gtgagccagg aagcgcgtaa
    21061 ctggctggcc gagaaaggtt acgaccgggc aatgggcgct cgtccgatgg cgcgtgtcat
    21121 ccaggacaac ctgaaaaaac cgctcgccaa cgaactgctg tttggttcgc tggtggacgg
    21181 cggtcaggtc accgtcgcgc tggataaaga gaaaaatgag ctgacttacg gattccagag
    21241 tgcacaaaag cacaaggcgg aagcagcgca ttaatctgat tgtcaggtag gttggtcaag
    21301 tccgtaatct cgaaagaggt tgcggacttt ttatttatgg ggtggaacgg tgaaaaccct
    21361 atttttggag gtgaaggtaa gttgttgata attagtgctg ctggaaaagg taaggataaa
    21421 aaagggtgac agcaggaaaa tgagatggtt ttgctttatt aacaacggac taaacgtgta
    21481 gtatttgagt tcactgccgt acaggcagct tagaaaggaa caatcttgca aaggctgtga
    21541 aagttggcgt tcactgccgt acaggcagct tagaaattca ctggtaacat actccacccg
    21601 cccaccatgt tcactgccgt acaggcagat aaaatgcgaa aaaaaaagct cgcactttcg
    21661 tacgagctct tctttaaata tggcggtgag ggggggattc gaacccccga tacgttgccg
    21721 tatacacact ttccaggcgt gctccttcag ccactcggac acctcaccaa attgttttgc
    21781 taccaaacct catgggtggc aacggggcgc tactataggg agttggagta aaacggtcaa
    21841 gaagaatttt aatgataatt attgtttgct catactgtaa acaagttgtg cagtatatct
    21901 acatcgagac aagttatgga cttatacttc caaagtactt catacatatc acaaaataaa
    21961 aaggccggtt aaaccgacct tttactcgtt ctttctcttc gcccatcagg cggtaaaaca
    22021 atcagcgact acggaagaca atgcggcctt tgctcaggtc gtacggggtc agttcaacag
    22081 tcactttgtc gcccgtcagg atgcggatgt agtttttgcg cattttaccg gagatgtgtg
    22141 cagtaaccac gtgaccgttt tctaactcta cgcggaacat ggtattaggc aacgtttcaa
    22201 gaacggtacc ttgcatttca atattgtctt ctttggccat ctaatcctct ggggtatcac
    22261 taccgtaatt tgaaccggca agataatgcc gaagttctgt aaataagtaa agatttgcgc
    22321 gctaaatcgc aacaaacagg ttcggcacat tactccgaaa acacacggct aagccgcacc
    22381 aaaagcgcaa cgtataaggg agcggtgaga taaacgatgg gcgttacctg acgcgaaaaa
    22441 ttccttatcg gcagcggggt aatgagcgta accaactctg cgaccgcaat tataacactc
    22501 tggggagaaa tgtgccgaaa acattcattc ttgtggtgaa aacaagcacc gtggtaccca
    22561 gaatttattc ggcaatcgtc cgaggcgcat ttgattgaga taattgaggt aatcccggcg
    22621 gggaatttcg caggcaccaa gcgacgctgt gtgatcgtta aggacctggc agtcgataag
    22681 tttaccgcca tgaccgataa attcctcaca gaataccaga agcgccgttt tagacgcatt
    22741 ttccatccgg ctgaacatgg actcgccaca aaatagtgtt ccctgggcca caccgtacat
    22801 accgccaaca agctcatctt cacaccagac ttcgatggag tgggcatgac cgagttcgtg
    22861 aagacgatgg taggcttcga ccacgccacg cgtgatccag gttccttctt cgcgatcgct
    22921 ggcacagcct tcaatgacct gaccaaaggc gtaattcatc gtgacacgat agggcgagcg
    22981 tttatgaaat cgtttcatac tacggctgat atgcaatgat tcaggccata gtaccgcgcg
    23041 aggatcgggc gaccaccaga ggatggggtc gcctggagaa aaccacggga aaataccacg
    23101 ctgataagcc attaacaggc gcgcagggct aagatcgccc cccagtgcca gcaggccgtt
    23161 aggctcacgt aatgcgcctt ccggggaagg gaaggctatt gaatggcgag aaagctgaac
    23221 caggcgcatg accgcaaaac tccacgcaag tcggatcgtt caataatagc ttacaaaccc
    23281 tgcttaaact ggtaataacg cccctgtctg gcaagcagtt ctgcgtgagt accttgctca
    23341 ataatttgcc cgttgtccat cactattatt tgttggaaac gagagagtcc gcgaagtcga
    23401 tgggtgacca ttaacaccgt tttctcgcac atcatttctg caagcaattc aaggatctga
    23461 ctttcggttg tggcatctaa gccttctgta ggttcatcca gcaataccag cggcgcatca
    23521 tgtaacagcg cacgggcgat agccagacgg cgcagttcac caccggagag ctggcgtccg
    23581 ccttcaccta accaactgtt gagacctgca tcctcgagca gcttctccag accaacgcga
    23641 cgtaagatct ccgccagagc ctcatcacta ctgccaggtg aggcgagtaa cagattatca
    23701 cgcagcgtgg cgctaaacag atgcactcgc tgtggcacaa cgctgatggt ctgtcgtaga
    23761 gtcgcttcat tcaggctggc tatggggcta tcgttaagca aaatctcgcc ctgttgcggg
    23821 tcccatgcgc gggtcagcag ttgtaacaat gttgatttgc cgcatccggt tcgcccgaga
    23881 atcgctatat gttctccggc gtttacctga agagaaatcc ctttaagtgc ctgttgggat
    23941 tgctccggat aagtgaactg aacatcccgt aacgtcagcg aaacgcgatc ggcaacacga
    24001 gtttgggtat cagggaaagt gacctccggt ttttgatccg ttaagtcagt gatccgtacg
    24061 gcagaggcaa tgacttgccc cagatgctga aatgcacccg ttactggtgc cagtgcttca
    24121 aacgcggcta acgcgcagaa gacaaacagg gcaattaacg cgccgggttg agcattgccg
    24181 ccaacgccgc cagacgccat ccacagcatc aggatcaccg ctaacgcgcc aatgagcagc
    24241 attatcgctt gtgacaatgc ggtgagttca gattgacgac gttgcgcttc cagccactga
    24301 atttcggtat tctctaactg cgtgcgataa cgatcgctgg caccaaaaat ggtcagctca
    24361 gcttgccctt gcagccaggc cgtcagttgt tggcgatact gcccgcgaag atgagtcaga
    24421 ttttgcccgg tgctttttcc cgcacgataa aacagtggtg gcataaggaa aagcgtcagt
    24481 aacataatgc cgcccagcgt aaaggcgagg gtgaaatcaa ggaaacttaa cccgattgtc
    24541 accaccataa tcaccacaaa agcgcctacc agcggtgaga taacgcgcag gtaaagatga
    24601 tcgagcgtat caacatccgc caccacgcgg ttgagtaatt cgccctgacg atagcgcgcc
    24661 agtccggcag gggagagggg cagtaatttg ctgaaggtgt aaatgcgcag atgctgcaac
    24721 acgcggaaag tcgcgtcgtg acttaccaga cgttcaaaat agcgcccggc agtacgggtg
    24781 attgctgcgc cacgcacgcc cgcagcgggt agcatatagt tgaagctgta cagtccggca
    24841 acccccgcta ccgctgaggc ggagaggaac cagccggaaa gtgtcaacag accgatactg
    24901 gcgagcagcg tgacaattgc cagcacaata ccaagactta acatccattt atgacgttta
    24961 tacagtgcca gatagggtag caaagcgcgc atttaaatct cctcctgacg atgggccagc
    25021 aatgtggcga aaggaccacc agccacgctt aattccgcgt aacgtccttg ctcaataatc
    25081 tgaccatcct gcattaccca aatgacatcc cagtcagcaa gatcttctaa ctggtgggtg
    25141 accattaacg ttgtctggcg cagagaggcg gcattaagcg cctccattac gcgctgttca
    25201 ctgtgagcat caaggctggc agcgggttca tccaacagta atagcgaaca gggatttagt
    25261 aatgctcggg ccaccgccac gcgctgtgcc tgccccacgg aaagacgggc agcctggtca
    25321 ccaacaggcg tatcaatgcc ttgcggcagg agcggtagaa actcactgac ccaggcgtta
    25381 tccagcgctg tttgtaactc ttgttcgctg gcatcaggtc gcgccagtag tacgttatcc
    25441 cgtaatgttg ctgccggtaa ttgtgggttt tgcccaaccc aggagagatg tttacgccat
    25501 gattccggtg ataaatcgcg taattctatc ccgttgattc gtagcgatcc ctgatatgag
    25561 agaaaaccag aaagcgcgtt cagcagtgag cttttacctg aaccgctgcg accaaccaac
    25621 actgcacgtt ggcctgctgg caaagtaaag ttcagcggtc cagccagcgt tttaccttct
    25681 ggtgatgtaa taaacagatc ctcggcttca atggtcaccg gatcggttga tgctaattcc
    25741 gcctcaccac gttgcggatg ggcgagcggg gtttccataa acgttttcag actgtcagct
    25801 gcgccaacag cctgggcttt agcatgataa aacgtaccga gatcgcgtaa tggctggaaa
    25861 aactccggcg caaggatcag ggccagaaaa cccgcagcca gcgtcacgcc agtatcgtag
    25921 tgaccaaaat ccagctcgcc gagataggaa aaaccaaagt agaccgccac cagcgcaatt
    25981 gacagcgagg taaaaaattc gagaatgccg gaggataaaa acgccagccg tagtacttcc
    26041 attgtccgtt ggcggaaatc ttccgaagca gaacgaatac tttcaatttc agcttcacca
    26101 cgaccaaaaa tacgcagtgt ttccatgccg cgcaggcgat cgaggaaatg cccacttaag
    26161 cgagcaagag cgagaaagtt acgtcggtta gcatcggcag cccccattcc aaccagcgcc
    26221 ataaacaacg gaattaacgg tgctgtgccc agcagaatga gcgccgcagc ccagttagag
    26281 gggaagatcg ccaccacaat cagcaacggc accgacactg ccagcgccat ttgcggcagg
    26341 tagcgtgcat agtaatcatg catatcgtca atttgctcga gtaccagcgt cgcccagctc
    26401 cccgccggtt taccctgaat ccacgctggc cctgcttgtt gcagacggtc gagaacctga
    26461 cggcggatgg caaagcggat atgctgcccg gcgtgataac ccacccgttc gcgtaaccag
    26521 accacccatg cgcgcagtac aaaggtcaga accagtaacg taaagggaag cagcagggct
    26581 tcacggggaa tattctccat aatcatatgt tgcagaattc gcgccatgaa ccaggcctgg
    26641 gcaatgatca atatgccgct cacaaagccc agcagacgag aaatattcag ccaacgttgg
    26701 gagatgacgc tttgctgttt taaccagcgg gttaactctt tttgacggga tttattcatt
    26761 gcacgcttag caggtgagtt atcagaatta tttgcagagc aatgttacaa cgaggaaaaa
    26821 ataaaggcga cccatagtcg catggtgtcg ccttctttac ttttgttact gatttgtaaa
    26881 attattttgc gtcagctaaa ccatcgaggt agcgttccgc atcaagtgct gccatgcagc
    26941 ctgtaccagc agatgtaata gcctggcgat aaatgtgatc catcacgtcg cctgcggcaa
    27001 agacgccagg gatgctggtc tgggtggcat taccatgaat acccgactgt actttgatgt
    27061 agccgttttc cagttccagc tgcccttcga aaatggcagt attcgggctg tgaccgatag
    27121 caacaaacag accggcaacg tcgagtgact cgatgttatc gctgttttgc gtatcgcgca
    27181 gacgaacgcc agtgacgccc atctgatcgc cggtcacctc ttccagcgta cggttggtgt
    27241 gtagaatgat gttgccgttc tccactttat ccatcagacg cttaataagg attttttccg
    27301 cgcggaaacc gtcacggcgg tgaatcagat gcacttccga agcgatgtta gacagataca
    27361 gcgcctcttc aaccgcggta ttgccgccgc cgatgaccgc aactttctgg ttgcgataga
    27421 agaaaccgtc gcaggtagca caagcagaaa ctccacggcc tttaaaggct tcttcagatg
    27481 gcaggccgag atagcgtgca gaagctccgg tggcaataat cagcgcgtcg caagtgtatt
    27541 cgccgctatc gccagtcaga cggaacggac gattctgcaa atcaactttg ttgatgtgat
    27601 caaagatgat ttcagtttca aatttggtgg catgttcgtg catgcgctcc attaataacg
    27661 gaccggtcag atcgtttgga tcgccaggcc agttttccac ttccgtggtg gtggtcagtt
    27721 ggccgccttt ttccatgccg gtaatcagca caggttgcag gttggcgcgc gccgcgtaga
    27781 cagcagcggt gtatcccgcc gggcctgaac ccaggataag cagtttactg tgtttggtcg
    27841 tgcccatgag atccccatag ttgttggcag acaatgggca ggattgtagg gaatttacag
    27901 acgtaaaaaa agagtatgac gattttgtta acaatttgtg caatcggcag catcgatagg
    27961 caggtcaaat tctcccgtca ttatcacctc tgctacttaa atttcccgct ttataagccg
    28021 attaaatgat gaataaacgc ccctgttaat gaatatctgg catgttgtac taaaaatcga
    28081 tgttttgctt tgacaatccc ctggtgtttt gcgaaaacat tcgaggaaga aaaaaacagt
    28141 attcttatat gcgcataacc atgcatgtaa ataccatgtt taccgtgcta gtgaaatcta
    28201 cgtatggcgt ggacagacgc cattcgtgat gtcgatagct gccacaaggc aacggtcttc
    28261 tcaccgtaga cccaggcatt gcgcgccgtg aatcttcatg atttcggtct atcgtgacgg
    28321 gtagcgactc tgaacagtga tgtttcaggg tcagacagga gtagggaagg aatacagaga
    28381 gacaataata atggtagata gcaagaagcg ccctggcaaa gatctcgacc gtatcgatcg
    28441 taacattctt aatgagttgc aaaaggatgg gcgtatttct aacgtcgagc tttctaaacg
    28501 tgtgggactt tccccaacgc cgtgccttga gcgtgtgcgt cggctggaaa gacaagggtt
    28561 tattcagggc tatacggcgc tgctgaaccc ccattatctg gatgcatcac ttctggtatt
    28621 cgttgagatt actctgaatc gtggcgcacc ggatgtgttt gaacaattca ataccgctgt
    28681 acaaaaactt gaagaaattc aggagtgtca tttagtatcc ggtgatttcg actacctgtt
    28741 gaaaacacgc gtgccggata tgtcagctta ccgtaagttg ttgggggaaa ccctgctgcg
    28801 tctgcctggc gtcaatgaca cacggacata cgttgttatg gaagaagtca agcagagtaa
    28861 tcgtctggtt attaagacgc gctaacacgg aacaggtgca aaatcggcgt attttgatta
    28921 cactcctgtt aatccataca gcaacagtac tggggtaacc tggtactgtt gtccgtttta
    28981 gcatcgggca ggaaaagcct gtaacctgga gagcctttct tgagccagga atacactgaa
    29041 gacaaagaag tcacattgac aaagttaagt agcggccgcc gccttctgga ggcgttgctg
    29101 atccttattg tcctgtttgc cgtctggttg atggctgcct tactaagctt taacccttcg
    29161 gaccccagct ggtcgcaaac ggcctggcat gaacctatcc ataatttagg tgggatgccc
    29221 ggtgcatggc tggcagatac gctgttcttt atttttggcg tgatggctta caccattccc
    29281 gtcattattg tcggcggttg ttggtttgcc tggcgtcatc agtccagcga cgaatacatt
    29341 gattattttg ccgtttcgct acgcatcatt ggcgttttgg cgctcatcct tacctcctgt
    29401 ggtctggcgg caatcaacgc tgacgatatc tggtattttg cctccggtgg cgtcattggc
    29461 agcttactga gcactacgct acaaccactg ctacacagta gcgggggaac tattgcactg
    29521 ctctgcgttt gggcagcggg cctgacgctg ttcaccggtt ggtcatgggt gaccattgct
    29581 gaaaaactcg gcggctggat tttaaatatt cttaccttcg ccagtaatcg tacccgtcgc
    29641 gatgatacct gggtcgatga agatgagtat gaagacgacg aagaatatga agaagatgaa
    29701 agtcacggca aacagcatga atcacgccgt gcccgtattc ttcgcggcgc gctagcgcgt
    29761 cgtaaacggt tggcggaaaa attcattaat ccgatggggc ggcaaacaga cgctgcgttg
    29821 ttctccggta agcggatgga tgatgacgaa gagattacct acactgcacg cggtgtggct
    29881 gccgaccctg acgacgtcct cttttcgggc aatcgtgcaa cgcagccaga atatgacgag
    29941 tacgatccat tattaaacgg tgcgccaatt accgaacctg ttgctgtagc agctgctgct
    30001 accacggcga cacaaagctg ggctgcaccg gttgaacctg tgactcagac gccgccagtt
    30061 gcctctgttg atgttccacc tacgcaacct acagtagcct ggcagcctgt accggggccg
    30121 caaacaggag aaccggttat tgcacctgca ccggaaggtt acccacagca gtcacaatat
    30181 gcgcagcctg cagtgcaata taatgagccg ctgcaacaac ctgtacagcc acagcagccg
    30241 tattatgcgc ctgcagcgga acagcctgtg caacaacctt actacgctcc tgcgccggaa
    30301 cagtctgcgc aacagccgta ttacgcccct gcgccagaac aatcggtggc aggtaacgcc
    30361 tggcaagccg aagagcagca atccactttt gctccacagt ctacatacca gactgagcaa
    30421 acttatcagc agccagccgc tcaggagccg ttgtaccaac agccgcaacc cgttgaacag
    30481 cagcctgttg tggagcctga acccgttgta gaagagacaa aacccgcgcg tccgccgctt
    30541 tactattttg aagaagtgga agagaagcgt gcccgtgaac gtgaacaact tgcggcctgg
    30601 tatcaaccga ttcctgaacc ggttaaagaa ccagaaccga tcaaatcttc gctgaaagca
    30661 ccttctgttg cagcagtacc tccagtggaa gccgctgccg ctgtttcccc tctggcatct
    30721 ggcgtgaaaa aagcgacact ggcgacgggg gctgccgcaa ccgttgccgc gccagtcttc
    30781 agtctggcaa atagcgctgg accgcgtccg caggtcaaag aggggattgg cccgcagttg
    30841 ccacgaccga aacgcatccg cgtgccaact cgtcgtgaac tggcgtctta cggtattaag
    30901 ctgccctcac agcgtgcggc agaagaaaaa gcccgtgaag ctcagcgcaa tcagtacgat
    30961 tccggcgatc agtataacga tgatgaaatc gatgcgatgc agcaggatga actggcacgt
    31021 cagttcgccc agacacagca gcaacgctat ggcgaacagt atcaacatga tgtgcccgtg
    31081 aacgcagaag atgcagatgc tgcggcagag gctgaactgg ctcgtcagtt tgctcaaact
    31141 caacaacaac gttattccgg cgaacaacct gctggggcga atccgttcac tctggatgat
    31201 tttgaatttt cgccaatgaa agcgttgctg gatgatggtc cacacgaacc gctgtttacg
    31261 ccaattgttg aacctgtaca gcagccgcaa caaccgattg caccgcagca acagtatcag
    31321 cagccgcagc aaccagttgc accgcagcag caatatcagc agccgcaaca gccggttgca
    31381 ccacagccgc aatatcagca gccgcaacag ccagttgcgc cgcagccgca gtatcagcag
    31441 ccacaacaac cggttgcgcc gcagccgcaa tatcagcagc cacaacagcc agttgcgccg
    31501 cagccgcagt atcagcagcc acaacagcca gttgcgccac agccgcagga taccctgctt
    31561 catccgctgt tgatgcgtaa tggcgacagc cgtccgttgc ataaaccgac gacgccgctg
    31621 ccttctctgg atttgttgac gccgccgccg agcgaagtgg agccggtaga tacccttgct
    31681 cttgaacaaa tggcgcgtct ggtggaagcg cgtctggctg atttccgtat taaagccgat
    31741 gtcgtcaatt attctccggg gccggttatc actcgctttg aattgaacct ggcaccgggc
    31801 gtaaaagcgg cgcgtatttc taacttgtca cgtgaccttg cccgttcact ttcgacggtg
    31861 gcggtgcgtg tcgttgaagt tattcctggc aaaccctatg taggtctgga gttaccgaat
    31921 aaaaaacgac aaaccgttta tctgcgtgaa gttttggata acgccaaatt ccgcgataat
    31981 ccgtcgccat taaccgtggt gctgggtaaa gatatcgccg gtgagccggt ggttgccgat
    32041 ctggcgaaaa tgccgcactt gttggttgcg gggactaccg gttccggtaa gtctgtcggt
    32101 gtgaacgcga tgatcctgag catgctttat aaagcacagc cagaagatgt tcgtttcatc
    32161 atgatcgacc cgaaaatgct ggagctttcg gtttatgaag gcattccaca cctgttaacg
    32221 gaagtcgtta ctgatatgaa agatgccgcc aacgcgctgc gctggtgtgt taacgagatg
    32281 gagcgtcgtt ataaactgat gtctgcgctg ggtgtgcgta atctggcggg ttataacgaa
    32341 aaaattgctg aagccgatag gatgatgcgt ccgattccag acccgtactg gaagccgggt
    32401 gacagtatgg atgcccagca tccggtgctg aaaaaagaac cgtacattgt ggtgttggtg
    32461 gacgaatttg ccgacctgat gatgacggta ggtaaaaaag tggaagagct gatagcacgt
    32521 ctggcgcaaa aagcccgtgc cgcgggtatc cacctcgtac tggcaacgca gcgtccatcg
    32581 gttgatgtta ttactggtct gattaaagcg aatattccga cccgtatcgc ctttaccgta
    32641 tccagtaaga ttgactcacg taccattctt gatcaggctg gcgcggaatc actgctgggt
    32701 atgggggata tgctttactc tgggccgaac tccacgttgc cggtacgtgt tcatggtgct
    32761 tttgttcgcg atcaggaagt tcatgccgtg gtgcaggact ggaaagcgcg tggccgccca
    32821 cagtatgttg atggcatcac ctccgacagt gaaagcgaag gtggcgcggg cggtttcgat
    32881 ggcgctgaag aactggatcc gttgttcgat caggcggtac agtttgtcac tgaaaaacgc
    32941 aaagcatcaa tttctggcgt acagcgtcag ttccgcattg gttataaccg tgcagcgcgt
    33001 attatcgaac agatggaagc gcaggggatt gtcagcgaac aggggcacaa cggtaatcgt
    33061 gaagtgctgg ccccaccgcc gtttgactaa ttaatgcatc gtatgccgga aaaggcgcgg
    33121 tagcgtcgca tccggcactc tatcaactga aaattcagta ttttcttctt tcctcaagct
    33181 gattattagc ctggaataga gagtagaggg agctcccggt cgggagtgac gtaatttgag
    33241 gaataatgat gaaaaaaatt gctatcacct gtgcattact ctcaagctta gtagcaagca
    33301 gcgtttgggc tgatgccgca agcgatctga aaagccgcct ggataaagtc agcagcttcc
    33361 acgccagctt cacacaaaaa gtgactgacg gtagcggcgc ggcggtgcag gaaggtcagg
    33421 gcgatctgtg ggtcaaacgt ccaaacttat tcaactggca tatgactcaa cctgacgaaa
    33481 gcattctggt ttctgacggt aaaacactgt ggttctataa cccgttcgtt gagcaagcta
    33541 cggcaacctg gctgaaagat gccaccggta atacgccgtt tatgctgatt gcccgcaacc
    33601 agtccagcga ctggcagcag tacaatatca aacagaatgg cgatgacttt gtcctgacgc
    33661 cgaaagccag caatggcaat ctgaagcagt tcaccattaa cgtgggacgt gatggcacaa
    33721 tccatcagtt tagcgcggtg gagcaggacg atcagcgcag cagttatcag ctgaaatccc
    33781 agcaaaatgg ggctgtggat gcagcgaaat ttaccttcac cccgccgcaa ggcgtcacgg
    33841 tagatgatca acgtaagtag aggcacctga gtgagcaatc tgtcgctcga tttttcggat
    33901 aatacttttc aacctctggc cgcgcgtatg cggccagaaa atttagcaca gtatatcggc
    33961 cagcaacatt tgctggctgc ggggaagccg ttgccgcgcg ctatcgaagc cgggcatttg
    34021 cattctatga tcctctgggg gccaccgggt accggcaaaa caaccctcgc tgaagtgatt
    34081 gcccgctatg cgaacgctga tgtggaacgt atttctgctg tcacctctgg cgtgaaagag
    34141 attcgcgagg cgattgagcg cgctcggcaa aaccgcaatg caggtcgccg cactattctt
    34201 tttgttgacg aagttcaccg tttcaacaaa agccagcagg atgcgtttct gccacatatt
    34261 gaagacggca ccatcacttt tattggtgca accactgaaa acccgtcatt tgagcttaat
    34321 tcggcactgc tttcccgtgc ccgtgtctat ctgctgaaat ccctcagtac aaaggatatt
    34381 gagcaagtac tgactcaggc gatggaagac aaaactcgtg gctatggtgg tcaggatata
    34441 gttctgccag atgaaacacg acgcgccatt gctgaactgg tgaatggcga cgcgcgccgg
    34501 gcgttaaata cgctggaaat gatggcggat atggccgaag tcgatgatag cggtaagcgg
    34561 gtcctgaagc ctgaattact gaccgaaatc gccggtgaac gtagcgcccg ctttgataac
    34621 aaaggcgatc gcttttacga tctcatttcc gcactgcata agtcggtacg tggtagcgca
    34681 cccgatgcgg cgctgtactg gtatgcgcga attattactg ccggaggcga tccgttatat
    34741 gtcgcgcgtc gctgtctggc gattgcgtct gaagatgtgg gtaatgctga tccacgagcg
    34801 atgcaggtgg caattgcggc ctgggattgc tttactcgcg ttggcccggc ggaaggtgaa
    34861 cgcgccattg ctcaggcgat tgtttacctc gcctgcgcgc caaaaagcaa cgctgtctac
    34921 accgcgttta aagccgcgct ggccgatgct cgcgaacgtc ccgattatga cgtgccggtt
    34981 catttgcgta atgcgccgac gaaattaatg aaggaaatgg gctacgggca ggaatatcgt
    35041 tacgctcatg atgaagcaaa cgcttatgct gccggtgagg tttatttccc gccggaaata
    35101 gcacaaacac gctattattt cccgacaaac aggggccttg aaggcaagat tggcgaaaag
    35161 ctcgcctggc tggctgaaca ggatcaaaat agccccataa aacgctaccg ttaatgttat
    35221 cgttgcggta atgttgttac tgtatccctg tggtcgcagg ctgtggccac atctcccatt
    35281 taattcgata agcacaggat aagcatgctc gatcccaatc tgctgcgtaa tgagccagac
    35341 gcagtcgctg aaaaactggc acgccggggc tttaagctgg atgtagataa gctgggcgct
    35401 cttgaagagc gtcgtaaagt attgcaggtc aaaacggaaa acctgcaagc ggagcgtaac
    35461 tcccgatcga aatccattgg ccaggcgaaa gcgcgcgggg aagatatcga gcctttacgt
    35521 ctggaagtga acaaactggg cgaagagctg gatgcagcaa aagccgagct ggatgcttta
    35581 caggctgaaa ttcgcgatat cgcgctaacc atccctaacc tgcctgcaga tgaagtgccg
    35641 gtaggtaaag acgaaaatga caacgttgaa gtcagccgct ggggcacccc gcgtgagttt
    35701 gactttgaag ttcgtgacca tgtgacgctg ggtgaaatgc actctggcct cgactttgca
    35761 gccgcagtta agttgaccgg ttcccgcttt gtggtaatga aagggcagat tgctcgcatg
    35821 caccgcgcac tgtcgcagtt tatgctggat ctgcataccg aacagcatgg ctacagtgag
    35881 aactatgttc cgtacctggt taaccaggac acgctgtacg gtacgggtca gctgccgaaa
    35941 tttgctggcg atctgttcca tactcgtccg ctggaagaag aagcagacac cagtaactat
    36001 gcgctgatcc caacggcaga agttccgctg accaacctgg tgcgcggtga aatcatcgat
    36061 gaagatgatc tgccaattaa gatgaccgcc cacaccccat gcttccgttc tgaagccggt
    36121 tcatatggtc gtgacacccg tggtctgatc cgtatgcacc agttcgacaa agttgaaatg
    36181 gtgcagatcg tgcgcccgga agactcaatg gcggcgctgg aagagatgac tggtcatgca
    36241 gaaaaagtcc tgcagttgct gggcctgccg taccgtaaaa tcatcctttg cactggcgac
    36301 atgggctttg gcgcttgcaa aacttacgac ctggaagtat ggatcccggc acagaacacc
    36361 taccgtgaga tctcttcctg ctccaacgtt tgggatttcc aggcacgtcg tatgcaggca
    36421 cgttgccgca gcaagtcgga caagaaaacc cgtctggttc ataccctgaa cggttctggt
    36481 ctggctgttg gtcgtacgct ggttgcagta atggaaaact atcagcaggc tgatggtcgt
    36541 attgaagtac cagaagttct gcgtccgtat atgaacggac tggaatatat tggctaatac
    36601 ccaatttttc tgaatctaaa aagcgcctgc gggcgctttt tttgtctccc tttgataccg
    36661 aacaataatt acgcctcact tacacgtaat actactttcg agtgaaaatc tacctatctc
    36721 tttgattttc aaattattcg atatatataa gcctatatag cgacctgcta tagaaataat
    36781 tacacaatac ggtttgttac tggaatcaat cgtgagcaag cttgagtgag ccattatgaa
    36841 aacgaaaatc cctgatgcgg tattggctgc tgaggtgagt cgccgtggtt tggtaaaaac
    36901 gacagcgatc ggcggcctgg caatggccag cagcgcatta acattacctt ttagtcggat
    36961 tgcgcacgct gttgatagtg cccttccggc aaagtcagac gaaaaggtaa tctggagcgc
    37021 ctgtacagtt aactgtggta gccgctgccc gctacgtatg cacgttgtgg acggtgaaat
    37081 taaatatgtt gaaacggata ataccggcga tgacaactat gacggcctgc accaggtgcg
    37141 cgcctgtctg cgtgggcgtt ccatgcgtcg ccgtgtctac aatccggacc gcctgaaata
    37201 tccgatgaaa cgagtcgggg cgcgcggtga aggcaaattc gagcgcatta gctgggaaga
    37261 agcctacgac atcatcgcga ccaatatgca gcgcctgatc aaagagtacg gcaacgagtc
    37321 tatctatctg aactatggta ccggtacgct gggcggcacc atgacccgct cctggccgcc
    37381 gggaaatacc ctggtcgctc gcctgatgaa ctgctgcggc ggttatctga accattacgg
    37441 tgactactct tccgcgcaaa ttgcggaagg tttgaactat acctacggcg gctgggcaga
    37501 tggtaacagc ccgtcggata tcgaaaacag taaactggta gtgctgtttg gtaataaccc
    37561 tggcgaaacg cgaatgagtg gcggtggggt gacttactat cttgaacagg cgcgtcagaa
    37621 atctaatgct cgcatgatca tcatcgatcc gcgctatacc gacaccggag ccgggcgcga
    37681 agatgagtgg atccccattc gtccgggaac agatgccgca ctggttaacg gtctggcgta
    37741 tgtcatgatc accgaaaacc tggtggatca ggcattcctc gataaatatt gcgttggcta
    37801 cgacgagaaa acactgccag ccagtgcgcc gaaaaatggt cactataaag cttatattct
    37861 gggtgacggg ccagatggcg tggctaaaac gccggaatgg gcctcgcaaa tcactggtgt
    37921 tccggcagac aaaatcatca aattggcccg tgaaatcggt agtaccaaac cggcgtttat
    37981 cagccaggga tggggcccgc agcgtcacgc taacggtgaa atcgcaaccc gtgctatctc
    38041 gatgctggcg attctgaccg gtaacgttgg tattaacgga ggcaacagtg gcgcgcgtga
    38101 aggttcatac agcttaccgt ttgtccgtat gccgaccctc gaaaacccga tccagaccag
    38161 catttcgatg tttatgtgga ccgatgccat tgaacgtggc ccggaaatga cagcgctgcg
    38221 tgatggtgtg cgcgggaaag ataagctgga tgtgccgatc aaaatgatct ggaactatgc
    38281 cggtaactgc ctgattaatc agcattctga aatcaaccgt acccatgaaa tccttcagga
    38341 tgataagaag tgcgagctga ttgtggttat cgactgccac atgacctcat cggcgaaata
    38401 cgctgacatc ctgctgcctg actgcaccgc ttcagaacag atggactttg cactggatgc
    38461 atcctgcggg aatatgtctt acgtgatttt caacgatcag gtgattaaac cgcgctttga
    38521 atgtaagacc atctatgaaa tgaccagcga actggcaaaa cgtcttggcg ttgagcaaca
    38581 gtttactgag ggccgtaccc aggaagagtg gatgcggcat ctgtatgccc agtcgcggga
    38641 agcgattcct gaactgccaa cgtttgaaga gttccgtaag caggggatct ttaaaaagcg
    38701 cgacccacaa gggcatcacg ttgcttataa agctttccgt gaagatccgc aggcaaatcc
    38761 actgaccacg ccatcgggga aaattgagat ttattcgcag gcgctggttg acattgccgc
    38821 tacctgggaa ttgtcagaag gtgatgtgat cgatccactg ccgatctaca cgccgggctt
    38881 tgaaagttat caggatccgc tgaacaaaca gtatccgctg cagcttacgg gtttccacta
    38941 taaatctcgc gttcactcaa cttacggcaa cgttgatgtg ctgaaagcag cttgccgtca
    39001 ggaaatgtgg atcaacccgc ttgatgcgca aaaacgcggt atcaacaacg gcgataaagt
    39061 caggatcttt aacgatcgtg gtgaggttca tattgaggcg aaagtgacgc cacgaatgat
    39121 gccgggtgtg gtcgcactgg gtgaaggtgc ctggtatgac ccggatacaa aacgtgtcga
    39181 taagggcggt tgtattaacg tactgaccac tcaacgtccg tctcctctcg ctaaggggaa
    39241 tccgtcacat acaaaccttg ttcaggttga aaaggtgtaa ggagtaaccg atgacaaccc
    39301 agtatggatt ttttattgat tccagccgtt gcaccggttg caaaacctgc gagctggcct
    39361 gtaaagacta caaagatttg acaccagaag tcagtttccg ccgcatttat gaatatgctg
    39421 gcggcgactg gcaggaagat aacggtgtct ggcaccagaa cgtgtttgcc tactatctgt
    39481 cgatttcatg taaccactgc gaagatccgg cttgtactaa agtctgcccg agcggtgcga
    39541 tgcataaacg tgaagatggt tttgttgtgg tcgatgaaga tgtgtgcatt ggctgccgct
    39601 actgccatat ggcttgcccg tatggcgcac cgcaatataa cgaaacgaaa ggccatatga
    39661 ccaaatgcga tggttgttat gaccgtgttg cggaggggaa aaagccgatc tgtgttgaat
    39721 cttgcccgct gcgggcgctg gatttcggcc ctatcgacga gctgcgtaaa aaacatggcg
    39781 atctggcggc cgttgcgccg ttgccgcgag ctcactttac caaaccgaat attgtgatca
    39841 aacccaatgc caacagccgc ccgaccgggg ataccactgg ctatctggca aacccgaagg
    39901 aggtgtgaga tgggaagtgg atggcatgaa tggccgctga tgatcttcac ggtcttcggg
    39961 caatgtgtag cgggtggttt tatcgttctg gctttggcgc tgctcaaagg cgacctgcga
    40021 gcagaagccc agcagcgtgt tattgcctgc atgtttggtt tatgggtgct gatgggcatt
    40081 ggctttatcg cctctatgct tcatcttggt tcaccgatgc gcgcctttaa ctcgctcaac
    40141 cgggtagggg cttcagcact cagtaacgaa atcgccagcg gttcgatctt ttttgctgtt
    40201 ggtggcatcg gctggttact ggcaatgctg aaaaagctgt caccggcatt gcgtacgctg
    40261 tggctggtgg tgacgatggt tcttggcgtc atctttgtct ggatgatggt gcgtgtgtat
    40321 aacagcattg ataccgttcc gacctggtac agcatctgga cgccgatggg cttcttcctg
    40381 acgatgttta tgggcggccc gttactgggt tacctgttgt tgagtctggc tggcgtcgat
    40441 ggctgggcga tgcgtctgct gccagcaatt tctgtactgg cactggtagt gagtggcgtg
    40501 atgtcagtga tgcagggcgc agagctggcg actattcata gttctgtgca gcaggccgca
    40561 gcgctggtgc cggactatgg tgcgctgatg tcctggcgga tcgtgctttt ggctgttgcc
    40621 ctgtgcttgt ggattgcacc acagctaaaa ggttatcagc ctgcggttcc gctactttcc
    40681 gtatcattca ttctgcttct ggcaggggaa ttaatcggtc gtggcgtatt ctatggtttg
    40741 catatgaccg tggggatggc cgtcgcaagc taatcataac aaccggggtt tcggccccgg
    40801 ttctctttta tttctgcttc gttaacgtgt cataactggt catcaaatta cgataatcag
    40861 gaatatggtt agagaacaac gtcgccagtc cttcaatatc attacgccag tcgcgatgca
    40921 gctcgcacgc cacgccgaac catgtcatca attgcgcacc agcttgcgac atgcgatccc
    40981 acgccgaatg ccgggtaatt tcattaaagg tccctgacgc gtcagtcacg acaaagacgt
    41041 caaacccttc ttcaatggct gaaagcgccg ggaatgccac gcaaacttcg gttaccacac
    41101 cggcaataat taactgtttt ttacctgtcg ctttgacagc ttttacaaaa tcttcgttat
    41161 cccaggcgtt aatatttccc gggcgagcaa tgtaaggtgc atcgggaaac tgtgctttca
    41221 gttctggaac taatgggccg ttaggaccgg tttcaaaact ggtggtaaga atagtaggta
    41281 agttgaaata cttagccagg tcacccagcg ccagcacgtt atttttaaac ttatcgggtt
    41341 cgatatcccg tacaagggaa agtaaaccag cctggtgatc aacaagcaaa acggcagcat
    41401 catttttatc aagacgaaca tacggtttgg tcatcctctt ctcctttcga gagtcagtgg
    41461 tacgtctgaa atcggtcaga cgcgatgcat tgctctgaaa gcatagacgg gaaatatgag
    41521 tttgctgtga ccatgaaatt tttcgactga acgaagcgta tgaaatttgt gttagatcaa
    41581 taaaaacaat cagatgagat taatcgtctc tccagcatta gcgttatgaa tgagtaatat
    41641 aaatcgataa tacctccgct gcgatatgcg cgtattttca cccattgaca atgtttttgg
    41701 cggtggcatg atgcgcatga aatttgaact tcctcacggt tttaattcat gtccacgtat
    41761 acccggcctg tcatgctttt gctgtctggc ctgcttttgt tgactctggc gatcgcagtg
    41821 ttaaatacac tcgtgccgct ttggctcgcc caggaacaca tgtccacatg gcaggtaggc
    41881 gttgtcagct catcctattt taccggcaac ctggtcggta cattgctgac agggtatgtc
    41941 attaagcgca ttggctttaa ccgcagctat tatctggcct ccttcatttt tgccgctggc
    42001 tgtgccggcc ttggcctgat gattggattc tggagctggt tggcttggcg ttttgtcgcc
    42061 ggcgtcggct gtgccatgat ttgggtggtt gttgagagcg cgctgatgtg cagtgggacg
    42121 tcacgtaacc gtgggcgttt gcttgctgcg tatatgatgg tttattacgt gggaacgttt
    42181 ttaggccagt tactggtcag caaagtctca accgagttga tgagtgtatt gccgtgggtt
    42241 acaggtttga cgttggcagg aatcttaccg ctgttgttta cgcgtgtcct gaatcagcag
    42301 actgaaaacc atgattcgac gtcaattacg tcaatgctaa aactccgtca ggcgcggctt
    42361 ggcgtgaatg gctgcattat ctcaggaatc gttctgggat ctctatatgg cctgatgccg
    42421 ctgtacctca atcacaaagg ggtgagcaat gccagcattg gtttctggat ggcggtactg
    42481 gtcagtgcgg gtatccttgg acaatggccg attggacgtc tggcggataa gtttggtcga
    42541 ctgctggtgt tgcgtgttca ggtctttgtc gtcattctcg gcagtatcgc gatgcttagc
    42601 caggcggcga tggccccagc gttattcatc ctcggtgccg ctggctttac gctatatccg
    42661 gtggcgatgg catgggcttg cgagaaagtt gaacatcatc aactggtggc gatgaaccag
    42721 gccttactgt tgagctatac tgtgggaagt ctgcttggcc cgtcatttac tgccatgcta
    42781 atgcagaatt tctccgataa tttattgttt atcatgatcg ccagcgtatc gtttatctat
    42841 ttgctgatgc tgcttcgcaa cgccggtcat acgccgaaac ccgttgctca cgtgtaaatg
    42901 aattcaagca gagtgtgaac ttactgtttc acactctgct tttttgtttc ttctatctga
    42961 cttgctttat tccaaatttt attcgtttaa aaataaaatg tgcagcaggt tataattttg
    43021 catttcgcta tttccgcact tcttatttgc cgcgcataat ccctcgtttt acagatgccc
    43081 ctttaatttt ggcgaaggat ttgtctatgg ctgggaatgt tcaggaaaaa cagctgcgat
    43141 ggtacaacat tgcgctgatg tcttttatca ctgtctgggg ttttggcaac gttgttaata
    43201 actatgccaa ccaggggctg gtggttgttt tttcatgggt gtttatcttt gcgctctatt
    43261 tcacacctta tgcgctaatt gttggtcagt taggttcgac cttcaaagat gggaagggcg
    43321 gggtcagtac ctggattaaa cacacgatgg gacccggact ggcttacctc gccgcgtgga
    43381 cctactgggt ggtgcatatt ccctatctgg cacaaaaacc ccaggcaata ctgattgcgc
    43441 tcggttgggc gatgaaaggc gacggttcgc taatcaaaga atattcagtc gtagcgttac
    43501 aggggttaac gctggtgctg tttatcttct ttatgtgggt tgcttcacgc ggtatgaaat
    43561 cgctgaaaat cgtcggttct gtggcaggga ttgcgatgtt tgttatgtcg ctcctgtatg
    43621 tggcgatggc ggtaaccgcg cctgcgatta ctgaagtgca tattgcgacc acaaacatta
    43681 cctgggaaac gttcattcct catatcgact ttacctacat caccactatt tcaatgctgg
    43741 ttttcgcggt tggcggagca gagaagattt ctccttacgt taatcaaacg cgcaacccag
    43801 gaaaagaatt tccaaaaggg atgttatgcc tggcggtgat ggttgcggtt tgtgccattc
    43861 tgggctcgct ggcgatgggg atgatgtttg attcgcgtaa tatcccggat gacttaatga
    43921 ctaacggtca gtattacgcc tttcagaaac tgggcgagta ttacaacatg ggtaatactt
    43981 taatggtgat ttacgccatt gcgaataccc tgggacaagt agctgcgctg gtattctcga
    44041 ttgatgcccc gcttaaagtg ctattaggtg atgctgacag caaatatatt ccagccagtc
    44101 tatgtcgtac caacgcttct ggtacgcccg ttaatggcta ttttctgacc ctggtgctgg
    44161 tggcaattct gattatgctg ccgactctcg gcatcggtga tatgaacaat ctctataaat
    44221 ggctgttgaa tcttaactcg gtagtgatgc cgctgcgtta tttatgggta tttgttgcat
    44281 ttattgcagt cattcgcctg gcgcagaaat ataagccgga atatgtcttt attcgtaata
    44341 agtctctggc aatgaccgtc gggatttggt gttttgcctt taccgctttt gcctgcctga
    44401 cggggatttt cccgaaaatg gaagccttca ccgcagagtg gaccttccag ttggcgctga
    44461 atgttgcaac gccgtttgtg ctggttggat taggactgat attcccgctg ctggcgcgta
    44521 aagcgaatag taaataatta ttgtggtcgg tgacgctgac tctggcagat ctgacccgtt
    44581 tttacataat cgagaaatgc gcgcaagccg caggacatat actggcggtt tggataatag
    44641 atctggaagc ctggacgctc tgtgatccag tcttccagta cacattctaa acgaccggta
    44701 tcaaggtact ccttgatctg ttcatagagc aaatacccga taccagcacc catcaaaacg
    44761 gcatccagtt cagcatcaac atcatccaga atgatatttc ctgcgacagc aatttccagc
    44821 tcctttgcaa attgccagtg gaaaggtttg ccgctgggat aacgaaaaac gacacattga
    44881 tgattaagca gatcatgagg atggcggggt ttgccatatc ttgcaaagta ctctggcgtt
    44941 gctgctacac ataatttcac tggtgggccg atcgccacgc tgatcatatc tttttcgacg
    45001 atgccactaa gtcgaacgcc agcgtcaaag ccctgctgga cgatatcaac aagagagtcg
    45061 tcagttgtga gctcgacttt aatatcagga tattcacgtg tgaaaccaac cagtaaaggc
    45121 attaaaaata tacgtgcagc tacccgggcg gcattgattt tgagcgtacc tgtcggtgtc
    45181 agacgaaaat cattcatctc atctaacatg atctgaattt cgtcgaaagc tgggcgcaat
    45241 cgttcataga gattagaacc cgcttccgtt aacgatacgc ttcgggttgt ccgattgaat
    45301 aagcgaattt taagacgttg ttccagtgtt ttaatactat ggctaatggc ggacgaggat
    45361 aagcctaact catcgcccgc tgcacgaaag ctttgattac gggccacagc aaagaaagtg
    45421 gcaaagtcag acatattcat ccgcattagt gaaaatcctt cattaactca tcctgaatca
    45481 tcacgtttac aggatgatgc cgcctgcgta aagtgcgctc cagaacttaa cgtggaggta
    45541 aaattatgca gtctgaacgt atttatttgg tatgggccca tcctcgtcat gattcattga
    45601 ccgcacatat tgctgatgcg atccatcagc gggcaatgga gcggaaaata caggtgacgg
    45661 aactcgattt atatcggcgt aatttcaacc cggtgatgac gccggaagat gaaccagact
    45721 ggaagaatat ggataaacgt tattctccag aggttcatca gctttattca gagctgcttg
    45781 aacatgacac gttagtggtg gtttttcctc tctggtggta cagcttcccg gcaatgctaa
    45841 aaggatatat tgacagagta tggaataatg gtctggctta tggagagggg cataaattac
    45901 cattcaataa agttcgttgg gtggcgttgg tagggggaga caaagagtca tttgtccaga
    45961 tgggctgggg aaaaaatata agcgattatt tgaaaaatat gtgcagttat cttggtattg
    46021 aagatgccga tgtcactttc ttgtgtaata cagtggtatt cgatggggaa gaacttcacg
    46081 cgagctatta tcagtcgtta ttatctcagg tacgggatat ggtagatgca ctataagatg
    46141 tattaaaaac gctgtagcag aatgaagcgc ggaataacaa agcggcaact caataaagtt
    46201 gccgctttac ggggaaatta gaacattacc ttatgaccgt actgctcaag aatgcctttc
    46261 acgcgttcca tggtctcttt cttcggtggt ttaacaccat caagtttgta ttcttcaccc
    46321 atcgccaccc atttgtgttt gcccagctcg tggtagggga gaagctcgat tttctcaacg
    46381 ttgcccatat cacgggtaaa ttcaccgagg cgatgcgctg aatcgtcatc gtcagaccag
    46441 cctgggacaa caacgtagcg gatccacacc ttcacatttt tattcgccag atatttagca
    46501 aactccagcg tgcggtggtt ggaaactcca accagatttt ggtggatctc gtcgttcatc
    46561 tgtttgagat cgagcattac caggtcggtt acttccagca gttcatcaat caccggatcg
    46621 taacgacgaa caaaaccgtt ggtgtccaga caggtatgaa tgccttcttt tttgcaggcg
    46681 cggaaccagt cacgaacaaa ctcagcttgt aggattgcct caccgccgga tgcggtaacg
    46741 ccgccgccgg aagcgttcat aaagtggcga taggtcacca cttccttcat caaatcttca
    46801 acggtaactt ctttaccgcc atgcgtatcc caggtgtcgc ggttatgaca atacaggcag
    46861 cgcatcaggc agccctggaa aaaggtgata aagcgaatac ccgggccgtc tacggttcca
    46921 caggattcaa aggagtgaat gcgaccaata actgacattg cggtgtttct ccagatgtgg
    46981 cccatctgag gccgtgttgg tgcgcagctc gaaggctacg tcgagtctgt tttggcagtc
    47041 accttaaagt atagatagct gacaaaaaag gctctcgtgc taaaaaaggc cccactttcg
    47101 tggagccttt attgtacgct ttttactgta cgatttcagt caaaactaat tacatagatt
    47161 gagtgaaggt acgagtaata acgtcctgct gctgttcttt agtcagcgag ttgaaacgta
    47221 ctgcgtagcc agatacacgg atggtcagct gcggatattt ttccgggttt tccatcgcgt
    47281 cgagcagcat ttcacggttc atcacgttaa cgttcaggtg ctgaccacct tcgatggatg
    47341 cttcgtggtg gaagtaacca tccatcagac cagccaggtt ggtcttacga acttcgtcgt
    47401 ctttacccag tgcgttcgga acgatagaga aggtgtagga gataccatct ttagcgtaag
    47461 caaacggcag tttagcaacg gaagtcagag aggctacagc acctttctgg tcacgaccgt
    47521 gcatcgggtt agcacccggt ccgaacggcg cgccagcacg acgaccgtct ggggtgttac
    47581 cagttttctt accatacaca acgttagaag tgatggtcag aacagactga gtcgggattg
    47641 cgtcacggta ggtgtgcagt ttctgaattt tcttcatgaa acgttctacc aggtcaacag
    47701 ccaggtcatc tacacgcgga tcgttgttac caaactgcgg gtattcgcct tcgatttcga
    47761 agtcgatagc cagaccgtct tcgtcacgaa tcggtttaac tttcgcatat ttgattgcag
    47821 acagggagtc tgcagcaacg gacagaccag cgataccaca cgccatggtg cggataacgt
    47881 cacggtcgtg cagcgccatc agagaggctt cgtagctgta cttgtcgtgc atgtagtgga
    47941 tgatgttcag tgcagtgatg tactgtttag ccagccagtc catgaagtga tccatgcgct
    48001 ccatcacttc atcgtagttc aggagatcgc ctttgatcgg ttcagacttc ggaccaacct
    48061 gcattttcag tttttcgtca acgccgccgt tgattgcgta cagcatggtt ttcgccaggt
    48121 ttgcacgcgc accgaagaac tgcatttgtt taccaacgat catcgggctt acgcagcaag
    48181 caatagcgta gtcatcgttg ttgaagtccg gacgcatcag gtcatcgttc tcatactgca
    48241 gagaagaggt gtcgatggac actttagcgg cgaatttctt gaagttcagc ggcagttttt
    48301 cagaccacag aatggtcatg ttcggttccg gagacggacc catggtgtac agggtgttca
    48361 ggaaacggaa gctgtttttg gtaaccaggg tacgaccgtc gaggcccata ccaccgatag
    48421 attcggttgc ccagatcggg tcgccagaga acagttcatc gtattccgga gtacgcagga
    48481 agcgaaccat acgcagtttc atgaccaggt ggtcaaccat ttcctgcgct tcttgttcgg
    48541 tgatcttgcc agctttcagg tcacgttcga tgtacacatc caggaaggtg gaggtacgac
    48601 cgaaggacat tgcagcaccg ttctgagact taacagcagc caggtagccg aagtaagtcc
    48661 actggatagc ttcctgagcg ttggtagccg gaccagagat gtcgtagccg tatttcgcag
    48721 ccatttcttt catctgaccc agagcgcggt gctgttcagc gatttcttcg cgcagacgga
    48781 tagtctgttc caggtttacg ccgttttcca gatcagcctg cagagaagtg aactgtgcca
    48841 gtttgtcttt catcaggtag tcgataccgt acagcgcaac gcgacggtag tcaccgatga
    48901 tacgaccacg gccatatgca tctggcagac cggtcagaac accagattta cggcaacgca
    48961 ggatgtccgg agtgtaaacg tcgaacacgc cctggttgtg agttttacgg tattcagtga
    49021 agattttttt gatcatcgga tccagttcgc ggttgtacgc tttgcaggaa ccttcgatca
    49081 ttttgatacc accgaacggg ataagagcac gtttcagcgg agcttcagtc tgcagaccaa
    49141 cgattttctc aagctgcttg ttgatgtagc cagcgtcgtg agaggtgatg gtggaagcaa
    49201 cagcggtgtc aaagtcaact ggcgcgtgag tgcggttttc cagtttaacg ccttccatta
    49261 ctttgtccca cagggtggtg gtcgcttcag tagcgccagc caggaaggac tcgtcaccct
    49321 cgtacggagt gtagtttttc tgaatgaagt cacggacgtt tacttcattc tgccagtcac
    49381 ctttggtaaa accttcccag gctgtggcta acttttcatt aagctcggac atgtaacacc
    49441 taccttctta agtggatttt ttatttactg cgtacttcga caaccattaa tggtggtcgt
    49501 tttcacgcag gtaaatgacc cagtatgtca acccaaccaa caaaccacca ccgataatgt
    49561 tgccgatcgt aaccggaatc aggttatcag tgatgaaatt catcacggtc aggtgagaaa
    49621 aattttccgg tgctgaaccg actgcggtcc aaaattccgg ggatgcgaag tcgcggatta
    49681 caatacccat cgggatcata aacatgtttg cgatactgtg ctcaaaaccg ctggcaacaa
    49741 acatcgcgac cggcaacacc ataatgaacg ctttatccat caggctgcgg ccagaataac
    49801 tcatccatac tgccagacat accatcaggt ttgccaggat accaaggcag acggcctcaa
    49861 taaaagtatg gtgcactttg tggtcggcgg tttgtaggac gtttagtccc cattgaccat
    49921 tcgcggtcat atactcgccg gaaagccaca ttaaaagtac aaacagcagt gcgccgacca
    49981 ggttgccaaa atagacattt agccagtttt tcgccaactg accccaggtg atgcgcccac
    50041 tcgccttagc aacaacaatc aacactgtgg aagtaaagag atcggctccg cagacaacac
    50101 aaagaatcag ccccagagag aagcaaatgc cgccaaccag ttttgccatg ccgaagggca
    50161 ttgttcctgt gccagtggtt gctgtgatat agaagacgaa tgcgattgag atgaaaacac
    50221 cggcggtaat cgccagatag aaagtcttaa gcggatgttt cgttgcttta tagacacctg
    50281 cctcttcggc cactttggcc attgctgcag gaagtaaaag atcaaaaggg ttgtcagctt
    50341 tcacactaac tctctcttta ttaagtcggc gacgagatac taacaaagca ttatagatga
    50401 gaaattgata tagatcatat ctcgcctggc ttataggccc gtaactcgca tggtttt
//
LOCUS       DADXDL010000021        49720 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.021, whole genome shotgun sequence.
ACCESSION   DADXDL010000021 DADXDL010000000
VERSION     DADXDL010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49720
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.021"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(62..1342)
                     /gene="hemL"
                     /locus_tag="IRB70_001547"
     CDS             complement(62..1342)
                     /gene="hemL"
                     /locus_tag="IRB70_001547"
                     /EC_number="5.4.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-1-semialdehyde 2,1-aminomutase"
                     /protein_id="HBC0631472.1"
                     /translation="MSKSENLYSAARELIPGGVNSPVRAFTGVGGTPLFIEKADGAYL
                     YDVDGKAYIDYVGSWGPMVLGHNHPAIRNAVIEAAERGLSFGAPTEMEVKMAQLVTEL
                     VPTMDMVRMVNSGTEATMSAIRLARGFTGRDKIIKFEGCYHGHADCLLVKAGSGALTL
                     GQPNSPGVPADFAKHTLTCTYNDLASVRAAFEQYPQEIACIIVEPVAGNMNCVPPLPE
                     FLPGLRALCDEFGALLIIDEVMTGFRVALAGAQDYYGVVPDLTCLGKIIGGGMPVGAF
                     GGRRDVMDALAPTGPVYQAGTLSGNPIAMAAGFACLNEVAQPGVHETLDELTTRLAEG
                     LLEAAEEAGIPLVVNHVGGMFGIFFTDAESVTCYQDVMACDVERFKRFFHMMLDEGVY
                     LAPSAFEAGFMSVAHSMEDINNTIDAARRVFAKL"
     gene            1567..2988
                     /gene="clcA"
                     /locus_tag="IRB70_001548"
     CDS             1567..2988
                     /gene="clcA"
                     /locus_tag="IRB70_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H(+)/Cl(-) exchange transporter ClcA"
                     /protein_id="HBC0631473.1"
                     /translation="MKTDTPSLETPQAARLRRRQLIRQLLERDKTPLAILFMAAVVGT
                     LVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFLVRKYAP
                     EAGGSGIPEIEGALEDQRPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQIGGNIGR
                     MVLDVFRLKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEEMRPQFRYTLISIKAV
                     FIGVIMSTIMYRIFNHEVALIDVGKLSDAPLNTLWLYLILGIIFGIFGPIFNKWVLGM
                     QDLLHRVHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLV
                     FIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQYHLEAGTFAIA
                     GMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAILA
                     RTLAKQEAEQLARSKAASASENT"
     gene            3012..3077
                     /locus_tag="IRB70_001549"
     CDS             3012..3077
                     /locus_tag="IRB70_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631474.1"
                     /translation="MAIIIGLEFAQLPMSFGAKYE"
     gene            3070..3414
                     /gene="erpA"
                     /locus_tag="IRB70_001550"
     CDS             3070..3414
                     /gene="erpA"
                     /locus_tag="IRB70_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster insertion protein ErpA"
                     /protein_id="HBC0631475.1"
                     /translation="MSDDVALPLEFTDAAANKVKSLIADEDNPNLKLRVYITGGGCSG
                     FQYGFTFDDQVNEGDMTIEKQGVGLVVDPMSLQYLVGGSVDYTEGLEGSRFIVTNPNA
                     KSTCGCGSSFSI"
     gene            complement(3461..4084)
                     /locus_tag="IRB70_001551"
     CDS             complement(3461..4084)
                     /locus_tag="IRB70_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRIC cation channel family protein"
                     /protein_id="HBC0631476.1"
                     /translation="MLVYWLDIVGTAVFAISGVLLAGKLRMDPFGVLVLGVVTAVGGG
                     TIRDMALDHGPVFWVKDPTDLVVAMVTSMLTIVLVRQPRRLPKWMLPVLDAVGLAVFV
                     GIGVNKAFNAEAGPLIAVCMGVITGVGGGIIRDVLAREIPMILRTEIYATACIIGGIV
                     HATAYYTFSVPLETASMMGMVVTLLIRLAAIRWHLKLPTFALDENGR"
     gene            complement(4122..4922)
                     /gene="btuF"
                     /locus_tag="IRB70_001552"
     CDS             complement(4122..4922)
                     /gene="btuF"
                     /locus_tag="IRB70_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter substrate-binding
                     protein BtuF"
                     /protein_id="HBC0631477.1"
                     /translation="MAKSLFRALVALSFLAPLWLNAAPRVITLSPANTELAFAAGITP
                     VGVSSYSDYPPQAQKIEQVSTWQGMNLERIVALKPDLVIAWRGGNAERQVDQLASLGI
                     KVMWVDATSIEQIANALRQLAPWSPQPDKAEQAAQSLLDQYAQLKAQYADKPKKRVFL
                     QFGINPPFTSGKESIQNQVLEVCGGENIFKDSRVPWPQVSREQVLARSPQAIVITGGS
                     DQIPKIKQYWGEQLKIPVIPLTSDWFERASPRIILAAQQLCNALSQVD"
     gene            complement(4915..5613)
                     /gene="mtnN"
                     /locus_tag="IRB70_001553"
     CDS             complement(4915..5613)
                     /gene="mtnN"
                     /locus_tag="IRB70_001553"
                     /EC_number="3.2.2.16"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/S-adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBC0631478.1"
                     /translation="MKIGIIGAMEEEVTLLRDKIENRQTISLGGCEIYTGQLNGTEVA
                     LLKSGIGKVAAALGATLLLEHCKPDVIINTGSAGGLAPTLKVGDIVVSDEARYHDADV
                     TAFGYEYGQLPGCPAGFKADDKLIAAAEACIAELNLNAVRGLIVSGDAFINGSVGLAK
                     IRHNFPQAIAVEMEATAIAHVCHNFNVPFVVVRAISDVADQQSHLSFDEFLAVAAKQS
                     SLMVESLVQKLAHG"
     gene            5697..7214
                     /gene="dgt"
                     /locus_tag="IRB70_001554"
     CDS             5697..7214
                     /gene="dgt"
                     /locus_tag="IRB70_001554"
                     /EC_number="3.1.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dGTPase"
                     /protein_id="HBC0631479.1"
                     /translation="MAQIDFRKKINWHRRYRSPQGVKTEHEILRIFESDRGRIINSPA
                     IRRLQQKTQVFPLERNAAVRTRLTHSMEVQQVGRYIAKEILSRLKELKLLEAYGLDEL
                     TGPFESIVEMSCLMHDIGNPPFGHFGEAAINDWFRQRLHPEDAESQPLTDDRCSVAAL
                     RLRDGEEPLNELRRKIRQDLCHFEGNAQGIRLVHTLMRMNLTWAQVGGILKYTRPAWW
                     RGETPETHHYLMKKPGYYLSEEAYIARLRKELNLALYSRFPLTWIMEAADDISYCVAD
                     LEDAVEKRIFTVEQLYHHLHEAWGQHEKGSLFSLVVENAWEKSRSNSLSRSTEDQFFM
                     YLRVNTLNKLVPYAAQRFIDNLPAIFAGTFNHALLEDASECSDLLKLYKNVAVKHVFS
                     HPDVEQLELQGYRVISGLLEIYRPLLSLSLSDFTELVEKERVKRFPIESRLFHKLSTR
                     HRLAYVEAVSKLPSDSPEFPLWEYYYRCRLLQDYISGMTDLYAWDEYRRLMAVEQ"
     gene            7344..8768
                     /gene="degP"
                     /locus_tag="IRB70_001555"
     CDS             7344..8768
                     /gene="degP"
                     /locus_tag="IRB70_001555"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegP"
                     /protein_id="HBC0631480.1"
                     /translation="MKKTTLALSALALSLGLALSPLSATAAETSSATTAQQMPSLAPM
                     LEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQGGQGGN
                     GGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKDPRS
                     DIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLNA
                     ENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNL
                     TSQMVEYGQVKRGELGIMGTELNSDLAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGD
                     VITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSST
                     IFNGIEGAEMSNKGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKV
                     LDSKPSVLALNIQRGDSTIYLLMQ"
     gene            8923..10080
                     /gene="cdaR"
                     /locus_tag="IRB70_001556"
     CDS             8923..10080
                     /gene="cdaR"
                     /locus_tag="IRB70_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308193.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CdaR"
                     /protein_id="HBC0631481.1"
                     /translation="MAGWHLDTKMAQDIVARTMRIIDTNINVMDARGRIIGSGDRERI
                     GELHEGALLVLSQGRVVDIDDAVARHLHGVRQGINLPLRLEGEIVGVIGLTGEPENLR
                     KYGELVCMTAEMMLEQSRLMHLLAQDSRLREELVMNLIQAEENTPALTEWAQRLGIDL
                     NQPRVVAIVEVDSGQLGVDSAMAELQQLQNALTTPERNNLVAIVSLTEMVVLKPALNS
                     FGRWDAEDHRKRVEQLITRMKEYGQLRFRVSLGNYFTGPGSIARSYRTAKTTMVVGKQ
                     RMPESRCYFYQDLMLPVLLDSLRGDWQANELARPLARLKAMDNNGLLRRTLAAWFRHN
                     VQPLATSKALFIHRNTLEYRLNRISELTGLDLGNFDDRLLLYVALQLDEER"
     gene            complement(10134..10520)
                     /locus_tag="IRB70_001557"
     CDS             complement(10134..10520)
                     /locus_tag="IRB70_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000272186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3461 family protein"
                     /protein_id="HBC0631482.1"
                     /translation="MYDNLKSLGITNPEEIDRYSLRQEANNDILKIYFQKDKGEFFAK
                     SVKFKYPRQRKTVVADGVGQGYKEVQEISPNLRYIIDELDQICQRDRSEVDLKRKILD
                     DLRHLESVVTNKISEIEADLEKLTRK"
     gene            complement(10682..11494)
                     /gene="yaeI"
                     /locus_tag="IRB70_001558"
     CDS             complement(10682..11494)
                     /gene="yaeI"
                     /locus_tag="IRB70_001558"
                     /EC_number="3.1.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414706.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase YaeI"
                     /protein_id="HBC0631483.1"
                     /translation="MISRRRFLQATAATIATGSGFSYMHYREPGWFELIRHRLAFFKD
                     NAAPFKILFLADLHYSRFVPLSLISDAIALGIEQKPDLILLGGDYVLFDMPLNFSAFS
                     DVLSPLAECAPTFACFGNHDRPVGTEKNHLIGETLKSVGITVLFNQATVIATPNRQFE
                     LVGTGDLWAGQCKPPPASEANLPRLVLAHNPDSKEVMRDDPWDLMLCGHTHGGQLRVP
                     LVGEPFAPVEDKRYVAGLNAFGERHIYTTRGVGSLYGLRLNSRPEVTMLELV"
     gene            complement(11548..12372)
                     /gene="dapD"
                     /locus_tag="IRB70_001559"
     CDS             complement(11548..12372)
                     /gene="dapD"
                     /locus_tag="IRB70_001559"
                     /EC_number="2.3.1.117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-succinyltransferase"
                     /protein_id="HBC0631484.1"
                     /translation="MQQLQNIIETAFERRAEITPANADTVTREAVNQVIALLDSGALR
                     VAEKIDGQWVTHQWLKKAVLLSFRINDNQVIEGAESRYFDKVPMKFANYDEARFQKEG
                     FRVVPPAAVRQGAFIARNTVLMPSYVNIGAYVDEGTMVDTWATVGSCAQIGKNVHLSG
                     GVGIGGVLEPLQANPTIIEDNCFIGARSEVVEGVIVEEGSVISMGVYIGQSTRIYDRE
                     TGEIHYGRVPAGSVVVSGNLPSKDGKYSLYCAVIVKKVDAKTRGKVGINELLRTID"
     gene            complement(12403..15075)
                     /gene="glnD"
                     /locus_tag="IRB70_001560"
     CDS             complement(12403..15075)
                     /gene="glnD"
                     /locus_tag="IRB70_001560"
                     /EC_number="2.7.7.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     uridylyltransferase/uridylyl-removing protein GlnD"
                     /protein_id="HBC0631485.1"
                     /translation="MNTLPEQYANTALPTLPGQPQNPCAWPSDELTVCGIKAHIDTFQ
                     RWLGDAFDNGISAEELIEARTEFIDQLLQRLWIEAGFSQIADLALVAVGGYGRGELHP
                     LSDIDLLILSRKKLPDDQAQKVGELLTLLWDVKLEVGHSVRTLEECMLEGLSDLTVAT
                     NLIESRLLIGDVALFLELQKHIFSEGFWPSDKFYAAKVEEQNQRHQRYHGTSYNLEPD
                     IKSSPGGLRDIHTLQWVARRHFGATSLDEMVGFGFLTSAERAELNECLHILWRIRFAL
                     HLVVSRYDNRLLFDRQLSVAQRLNYSGEGNEPVERMMKDYFRVTRRVSELNQMLLQLF
                     DEAILALPADEKPRPIDDEFQLRGTLIDLRDETLFMRQPEAILRMFYTMVRNSAITGI
                     YSTTLRQLRHARRHLQQPLCNIPEARKLFLSILRHPGAVRRGLLPMHRHSVLGAYMPQ
                     WSHIVGQMQFDLFHAYTVDEHTIRVMLKLESFASEETRQRHPLCVDVWPRLPSTELIF
                     IAALFHDIAKGRGGDHSILGAQDVVHFAELHGLNSRETQLVAWLVRQHLLMSVTAQRR
                     DIQDPEVIKQFAEEVQTENRLRYLVCLTVADICATNETLWNSWKQSLLRELYFATEKQ
                     LRRGMQNTPDMRERVRHHQLQALALLRMDNIDEEALHQIWSRCRANYFVRHSPNQLAW
                     HARHLLQHDLSKPLVLLSPQATRGGTEIFIWSPDRPYLFAAVCAELDRRNLSVHDAQI
                     FTTRDGMAMDTFIVLEPDGSPLSADRHEVIRFGLEQVLTQSSWQPPQPRRQPAKLRHF
                     TVETEVTFLPTHTDRKSFLELIALDQPGLLARVGKIFADLGISLHGARITTIGERVED
                     LFIIATADRRALNNELQQEVHQRLTEALNPNDKG"
     gene            complement(15137..15931)
                     /gene="map"
                     /locus_tag="IRB70_001561"
     CDS             complement(15137..15931)
                     /gene="map"
                     /locus_tag="IRB70_001561"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBC0631486.1"
                     /translation="MAISIKTPEDIEKMRVAGRLAAEVLEMIEPYVKPGVSTGELDRI
                     CNDYIVNEQHAVSACLGYHGYPKSVCISINEVVCHGIPDDAKLLKDGDIVNIDVTVIK
                     DGFHGDTSKMFIVGKPTIMGERLCRITQESLYLALRMVKPGINLREIGAAIQKFVEAE
                     GFSVVREYCGHGIGRGFHEEPQVLHYDSRETNVVLKPGMTFTIEPMVNAGKKEIRTMK
                     DGWTVKTKDRSLSAQYEHTIVVTDNGCEILTLRKDDTIPAIISHDE"
     gene            16299..17024
                     /gene="rpsB"
                     /locus_tag="IRB70_001562"
     CDS             16299..17024
                     /gene="rpsB"
                     /locus_tag="IRB70_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBC0631487.1"
                     /translation="MATVSMRDMLKAGVHFGHQTRYWNPKMKPFIFGARNKVHIINLE
                     KTVPMFNEALAELNKIASRKGKILFVGTKRAASEAVKDAALSCDQFFVNHRWLGGMLT
                     NWKTVRQSIKRLKDLETQSQDGTFDKLTKKEALMRTRELEKLENSLGGIKDMGGLPDA
                     LFVIDADHEHIAIKEANNLGIPVFAIVDTNSDPDGVDFVIPGNDDAIRAVTLYLGAVA
                     ATVREGRSQDLASQAEESFVEAE"
     gene            17159..18010
                     /gene="tsf"
                     /locus_tag="IRB70_001563"
     CDS             17159..18010
                     /gene="tsf"
                     /locus_tag="IRB70_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBC0631488.1"
                     /translation="MAEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKS
                     GAIKAAKKAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAVA
                     GKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGARIGVLVAAKG
                     ADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDIAMQSGKPKEIAEKMVEG
                     RMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNAEVTGFIRFEVGEGIEKVETDFAAEV
                     AAMSKQS"
     gene            18157..18882
                     /gene="pyrH"
                     /locus_tag="IRB70_001564"
     CDS             18157..18882
                     /gene="pyrH"
                     /locus_tag="IRB70_001564"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000224576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBC0631489.1"
                     /translation="MATNAKPVYKRILLKLSGEALQGTEGFGIDASILDRMAQEIKEL
                     VELGIQVGVVIGGGNLFRGAGLAKAGMNRVVGDHMGMLATVMNGLAMRDALHRAYVNA
                     RLMSAIPLNGVCDSYSWAEAISLLRNNRVVILSAGTGNPFFTTDSAACLRGIEIEADV
                     VLKATKVDGVFTADPAKDPTATMYEQLTYSEVLEKELKVMDLAAFTLARDHKLPIRVF
                     NMNKPGALRRVVMGEKEGTLITE"
     gene            19032..19589
                     /gene="frr"
                     /locus_tag="IRB70_001565"
     CDS             19032..19589
                     /gene="frr"
                     /locus_tag="IRB70_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBC0631490.1"
                     /translation="MISDIRKDAEVRMDKCVEAFKTQISKIRTGRASPSLLDGIVVEY
                     YGTPTPLRQLASVTVEDSRTLKINVFDRSMSPAVEKAIMASDLGLNPNSAGSDIRVPL
                     PPLTEERRKDLTKIVRGEAEQARVAVRNVRRDANDKVKALLKDKEISEDDDRRSQDDV
                     QKLTDAAIKKIEAALADKEAELMQF"
     gene            19681..20877
                     /gene="ispC"
                     /locus_tag="IRB70_001566"
     CDS             19681..20877
                     /gene="ispC"
                     /locus_tag="IRB70_001566"
                     /EC_number="1.1.1.267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate reductoisomerase"
                     /protein_id="HBC0631491.1"
                     /translation="MKQLTILGSTGSIGCSTLDVVRHNPEHFRVVALVAGKNVTRMVE
                     QCLEFSPRYAVMDDEASAKLLKTMLQQQGSRTEVLSGQQAACDMAALEDVDQVMAAIV
                     GAAGLLPTLAAIRAGKTILLANKESLVTCGRLFMDAVKQSKAQLLPVDSEHNAIFQSL
                     PQPIQHNLGYADLEQNGVVSILLTGSGGPFRETPLRDLATMTPDQACRHPNWSMGRKI
                     SVDSATMMNKGLEYIEARWLFNASASQMEVLIHPQSVIHSMVRYQDGSVLAQLGEPDM
                     RTPIAHTMAWPNRVNSGVKPLDFCKLSALTFAAPDYDRYPCLKLAMEAFEQGQAATTA
                     LNAANEITVAAFLAQQIRFTDIAALNLSVLEKMDMREPQCVDDVLSVDANAREVARKE
                     VMRLAS"
     gene            21066..21824
                     /gene="ispU"
                     /locus_tag="IRB70_001567"
                     /gene_synonym="uppS"
     CDS             21066..21824
                     /gene="ispU"
                     /locus_tag="IRB70_001567"
                     /gene_synonym="uppS"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2E,6E)-farnesyl-diphosphate-specific
                     ditrans,polycis-undecaprenyl-diphosphate synthase"
                     /protein_id="HBC0631492.1"
                     /translation="MLSATQPLSEKLPAHGCRHVAIIMDGNGRWAKKQGKIRAFGHKA
                     GAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVKSLHRH
                     NVRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEK
                     VQQGNLQPDQIDEEMLNQHVCMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDV
                     LWPDFDEQDFEGALNAFANRERRFGGTEPGDETA"
     gene            21837..22694
                     /gene="cdsA"
                     /locus_tag="IRB70_001568"
     CDS             21837..22694
                     /gene="cdsA"
                     /locus_tag="IRB70_001568"
                     /EC_number="2.7.7.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414717.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBC0631493.1"
                     /translation="MLKYRLISAFVLIPVVIAALFLLPPVGFAIVTLVVCMLAAWEWG
                     QLSGFTTRAQRVWLAVLCGLLLALMLFLLPEYHRNIHQPLVEISLWASLGWWIVALLL
                     VLFYPGSAAIWRNSKTLRIIFGVLTIVPFFWGMLALRAWHYDENHYSGAIWLLYVMIL
                     VWGADSGAYMFGKLFGKHKLAPKVSPGKTWQGFIGGLATAAVISWGYGMWANLDVAPV
                     TLLICSIVAALASVLGDLTESMFKREAGIKDSGHLIPGHGGILDRIDSLTAAVPVFAC
                     LLLLVFRTL"
     gene            22706..24058
                     /gene="rseP"
                     /locus_tag="IRB70_001569"
     CDS             22706..24058
                     /gene="rseP"
                     /locus_tag="IRB70_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma E protease regulator RseP"
                     /protein_id="HBC0631494.1"
                     /translation="MLSFLWDLASFIVALGVLITVHEFGHFWVARRCGVRVERFSIGF
                     GKALWRRTDKLGTEYVIALIPLGGYVKMLDERAEPVVPELRHHAFNNKSVGQRAAIIA
                     AGPVANFIFAIFAYWLVFIIGVPGVRPVVGEIAANSIAAEAQIAPGTELKAVDGIETP
                     DWDAVRLQLVDKIGDESTTITVAPFGSDQRRDVKLDLRHWAFEPDKEDPVTSLGIRPR
                     GPQIEPVLENVQPNSAASKAGLQAGDRIVKVDGQPLTQWVTFVMLVRDNPGKSLALEI
                     ERQGNPLSLTLIPESKPGNGKAIGFVGIEPKVIPLPDEYKVVRQYGPFNAIVEATDKT
                     WQLMKLTVSMLGKLITGDVKLNNLSGPISIAKGAGMTAELGVVYYLPFLALISVNLGI
                     INLFPLPVLDGGHLLFLAIEKIKGGPVSERVQDFCYRIGSILLVLLMGLALFNDFSRL
                     "
     gene            24088..26520
                     /gene="bamA"
                     /locus_tag="IRB70_001570"
     CDS             24088..26520
                     /gene="bamA"
                     /locus_tag="IRB70_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamA"
                     /protein_id="HBC0631495.1"
                     /translation="MAMKKLLIASLLFSSATVYGAEGFVVKDIHFEGLQRVAVGAALL
                     SMPVRTGDTVNDEDISNTIRALFATGNFEDVRVLRDGDTLLVQVKERPTIASITFSGN
                     KSVKDDMLKQNLEASGVRVGESLDRTTIADIEKGLEDFYYSVGKYSASVKAVVTPLPR
                     NRVDLKLVFQEGVSAEIQQINIVGNHAFTTDELISHFQLRDEVPWWNVVGDRKYQKQK
                     LAGDLETLRSYYLDRGYARFNIDSTQVSLTPDKKGIYVTVNITEGDQYKLSGVEVSGN
                     LAGHSAEIEQLTKIEPGELYNGTKVTKMEDDIKKLLGRYGYAYPRVQSMPEINDADKT
                     VKLRVNVDAGNRFYVRKIRFEGNDTSKDAVLRREMRQMEGAWLGSDLVDQGKERLNRL
                     GFFETVDTDTQRVPGSPDQVDVVYKVKERNTGSFNFGIGYGTESGVSFQAGVQQDNWL
                     GTGYAVGINGTKNDYQTYAELSVTNPYFTVDGVSLGGRLFYNDFQADDADLSDYTNKS
                     YGTDVTLGFPINEYNSLRAGLGYVHNSLSNMQPQVAMWRYLYSMGEHPSTSDQDNSFK
                     TDDFTFNYGWTYNKLDRGYFPTDGSRVNLTGKVTIPGSDNEYYKVTLDTATYVPIDDD
                     HKWVVLGRTRWGYGDGLGGKEMPFYENFYAGGSSTVRGFQSNTIGPKAVYFPHQASNY
                     DPDYDYECATQDGAKDLCKSDDAVGGNAMAVASLEFITPTPFISDKYANSVRTSFFWD
                     MGTVWDTNWDSSQYSGYPDYSDPSNIRMSAGIALQWMSPLGPLVFSYAQPFKKYDGDK
                     AEQFQFNIGKTW"
     gene            26642..27127
                     /gene="skp"
                     /locus_tag="IRB70_001571"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
     CDS             26642..27127
                     /gene="skp"
                     /locus_tag="IRB70_001571"
                     /gene_synonym="hlpA"
                     /gene_synonym="ompH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone Skp"
                     /protein_id="HBC0631496.1"
                     /translation="MKKWLLAAGLGLALATSAQAADKIAIVNMGSLFQQVAQKTGVSN
                     TLENEFKGRASELQRMETDLQAKMKKLQSMKAGSDRTKLEKDVMAQRQTFAQKAQAFE
                     QDRARRSNEERGKLVTRIQTAVKSVANSQDIDLVVDANAVAYNSSDVKDITADVLKQV
                     K"
     gene            27131..28156
                     /gene="lpxD"
                     /locus_tag="IRB70_001572"
     CDS             27131..28156
                     /gene="lpxD"
                     /locus_tag="IRB70_001572"
                     /EC_number="2.3.1.191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-3-O-(3-hydroxymyristoyl)glucosamine
                     N-acyltransferase"
                     /protein_id="HBC0631497.1"
                     /translation="MPSIRLADLAQQLDAELHGDGDIVITGVASMQSAQTGHITFMVN
                     PKYREHLGLCQASAVVMTQDDLPFAKSAALVVKNPYLTYARMAQILDTTPQPAQNIAP
                     SAVIDATAKLGNNVSIGANAVIESGVELGDNVIIGAGCFVGKNSKIGAGSRLWANVTI
                     YHEIQIGQNCLIQSGTVVGADGFGYANDRGNWVKIPQIGRVIIGDRVEIGACTTIDRG
                     ALDDTVIGNGVIIDNQCQIAHNVVIGDNTAVAGGVIMAGSLKIGRYCMIGGASVINGH
                     MEICDKVTVTGMGMVMRPITEPGVYSSGIPLQPNKVWRKTAALVMNIDDMSKRLKSLE
                     RKVNQQD"
     gene            28261..28716
                     /gene="fabZ"
                     /locus_tag="IRB70_001573"
     CDS             28261..28716
                     /gene="fabZ"
                     /locus_tag="IRB70_001573"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000210741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBC0631498.1"
                     /translation="MTTNTHTLQIEEILELLPHRFPFLLVDRVLDFEEGRFLRAVKNV
                     SVNEPFFQGHFPGKPIFPGVLILEAMAQATGILAFKSVGKLEPGELYYFAGIDEARFK
                     RPVVPGDQMIMEVTFEKTRRGLTRFKGVALVDGKVVCEATMMCARSREA"
     gene            28720..29508
                     /gene="lpxA"
                     /locus_tag="IRB70_001574"
     CDS             28720..29508
                     /gene="lpxA"
                     /locus_tag="IRB70_001574"
                     /EC_number="2.3.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-ACP--UDP-N-acetylglucosamine
                     O-acyltransferase"
                     /protein_id="HBC0631499.1"
                     /translation="MIDKSAFVHPTAIVEEGASIGANAHIGPFCIVGPHVEIGEGTVL
                     KSHVVVNGHTKIGRDNEIYQFASIGEVNQDLKYAGEPTRVEIGDRNRIRESVTIHRGT
                     VQGGGLTKVGSDNLLMINAHIAHDCTVGNRCILANNATLAGHVSVDDFAIIGGMTAVH
                     QFCIIGAHVMVGGCSGVAQDVPPYVIAQGNHATPFGVNIEGLKRRGFSREAITAIRNA
                     YKLIYRSGKTLDEVKPEIAELAETYPEVKAFTDFFARSTRGLIR"
     gene            29508..30656
                     /gene="lpxB"
                     /locus_tag="IRB70_001575"
     CDS             29508..30656
                     /gene="lpxB"
                     /locus_tag="IRB70_001575"
                     /EC_number="2.4.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-A-disaccharide synthase"
                     /protein_id="HBC0631500.1"
                     /translation="MTEQRPLTIALVAGETSGDILGAGLIRALKERVPNARFVGVAGP
                     RMQAEGCEAWYEMEELAVMGIVEVLGRLRRLLHIRADLTKRFGELKPDVFVGIDAPDF
                     NITLEGNLKKQGIKTIHYVSPSVWAWRQKRVFKIGRATDLVLAFLPFEKAFYDKYNVP
                     CRFIGHTMADAMPLDPDKNGARDVLGISHDAHCLALLPGSRGAEVEMLSADFLKTAQL
                     LRQTYPDLEIVVPLVNAKRREQFERIKAEVAPDLSVHMLDGLGREAMVASDAALLASG
                     TAALECMLAKCPMVVGYRMKPFTFWLAKRLVKTDYVSLPNLLAGRELVKELLQEECEP
                     QKLAAALLPLLANGKTSHAMHDTFRELHQQIRCNADEQAAQAVLELAQ"
     gene            30653..31249
                     /gene="rnhB"
                     /locus_tag="IRB70_001576"
     CDS             30653..31249
                     /gene="rnhB"
                     /locus_tag="IRB70_001576"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBC0631501.1"
                     /translation="MIEFVYPHTQLVAGVDEVGRGPLVGAVVTAAVILDPSRPIAGLN
                     DSKKLSEKRRLALCEEIKEKALSWSLGRAEPHEIDELNILHATMLAMQRAVAGLHIAP
                     EYVLIDGNRCPKLPMPAMAVVKGDSRVPEISAASILAKVTRDAEMAALDIVFPQYGFA
                     QHKGYPTAFHLEKLAEYGATEHHRRSFGPVKRALGLAS"
     gene            31286..34768
                     /gene="dnaE"
                     /locus_tag="IRB70_001577"
     CDS             31286..34768
                     /gene="dnaE"
                     /locus_tag="IRB70_001577"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBC0631502.1"
                     /translation="MSEPRFVHLRVHSDYSMIDGLAKTAPLVKKAAALGMPALAITDF
                     TNLCGLVKFYGAGHGAGIKPIVGADFNVQCDLLGDELTHLTVLAANNTGYQNLTLLIS
                     KAYQRGYGAAGPIIDRDWLIELNEGLILLSGGRMGDVGRSLLRGNSALVDECVAFYEE
                     HFPDRYFLELIRTGRPDEESYLHAAVELAEARGLPVVATNDVRFIDSSDFDAHEIRVA
                     IHDGFTLDDPKRPRNYSPQQYMRSEEEMCELFADIPEALANTVEIAKRCNVTVRLGEY
                     FLPQFPTGDMSTEDYLVKRAKEGLEERLAFLFPDEEERLKRRPEYDERLETELQVINQ
                     MGFPGYFLIVMEFIQWSKDNGVPVGPGRGSGAGSLVAYALKITDLDPLEFDLLFERFL
                     NPERVSMPDFDVDFCMEKRDQVIEHVADMYGRDAVSQIITFGTMAAKAVIRDVGRVLG
                     HPYGFVDRISKLIPPDPGMTLAKAFEAEPQLPEIYEADEEVKALIDMARKLEGVTRNA
                     GKHAGGVVIAPTKITDFAPLYCDEEGKHPVTQFDKSDVEYAGLVKFDFLGLRTLTIIN
                     WALEMINKRRAKNGEPPLDIAAIPLDDKKSFDMLQRSETTAVFQLESRGMKDLIKRLQ
                     PDCFEDMIALVALFRPGPLQSGMVDNFIDRKHGREEISYPDVQWQHESLKPVLEPTYG
                     IILYQEQVMQIAQVLSGYTLGGADMLRRAMGKKKPEEMAKQRSVFAEGAEKNGINAEL
                     AMKIFDLVEKFAGYGFNKSHSAAYALVSYQTLWLKAHYPAEFMAAVMTADMDNTEKVV
                     GLVDECWRMGLKILPPDINSGLYHFHVNDDGEIVYGIGAIKGVGEGPIEAIIEARNKG
                     GYFRELFDLCARTDTKKLNRRVLEKLIMSGAFDRLGPHRAALMNSLGDALKAADQHAK
                     AEAIGQADMFGVLAEEPEQIEQSYASCQPWPEQVVLDGERETLGLYLTGHPINQYLKE
                     IERYVGGVRLKDMHPTERGKVITAAGLVVAARVMVTKRGNRIGICTLDDRSGRLEVML
                     FTDALDKYQQLLEKDRILIVSGQVSFDDFSGGLKMTAREVMDIDEAREKYARGLAISL
                     TDRQIDDQLLNRLRQSLEPHRSGTIPVHLYYQRADARARLRFGATWRVSPSDRLLNDL
                     RGLIGSEQVELEFD"
     gene            34781..35740
                     /gene="accA"
                     /locus_tag="IRB70_001578"
     CDS             34781..35740
                     /gene="accA"
                     /locus_tag="IRB70_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBC0631503.1"
                     /translation="MSLNFLDFEQPIAELEAKIDSLTAVSRQDEKLDINIDEEVHRLR
                     EKSVELTRKIFADLGAWQIAQLARHPQRPYTLDYVRLAFDEFDELAGDRAYADDKAIV
                     GGIARLDGRPVMIIGHQKGRETKEKIRRNFGMPAPEGYRKALRLMQMAERFKMPIITF
                     IDTPGAYPGVGAEERGQSEAIARNLREMSRLSVPTICTVIGEGGSGGALAIGVGDKVN
                     MLQYSTYSVISPEGCASILWKSADKAPLAAEAMGIIAPRLKELKLIDSIIPEPLGGAH
                     RNPEAMAASLKAQLLADLADLDVLSTEDLKNRRYQRLMSYGYA"
     gene            35839..37980
                     /gene="ldcC"
                     /locus_tag="IRB70_001579"
     CDS             35839..37980
                     /gene="ldcC"
                     /locus_tag="IRB70_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase LdcC"
                     /protein_id="HBC0631504.1"
                     /translation="MNIIAIMGPHGVFYKDEPIKELESALVAQGFQIIWPQNSVDLLK
                     FIEHNPRICGVIFDWDEYSLDLCSDINQLNEYLPLYAFINTHSTMDVSVQDMRMALWF
                     FEYALGQAEDIAIRMRQYTDEYLDNITPPFTKALFTYVKERKYTFCTPGHMGGTAYQK
                     SPVGCLFYDFFGGNTLKADVSISVTELGSLLDHTGPHLEAEEYIARTFDAEQSYIVTN
                     GTSTSNKIVGMYAAPSGSTLLIDRNCHKSLAHLLMMNDVVPVWLKPTRNALGILGGIP
                     RREFSRDSIEEKVAATTQAQWPVHAVITNSTYDGLLYNTDWIKQTLDVPSIHFDSAWV
                     PYTHFHPIYQGKSGMSGERVAGKVIFETQSTHKMLAALSQASLIHIKGEYDEEAFNEA
                     FMMHTTTSPSYPIVASVETAAAMLRGNPGKRLINRSVERALHFRKEVQRLREESDGWF
                     FDIWQPPQVDEAECWPVAPGEQWHGFNDADADHMFLDPVKVTILTPGMDEQGNMSEEG
                     IPAALVAKFLDERGIVVEKTGPYNLLFLFSIGIDKTKAMGLLRGLTEFKRSYDLNLRI
                     KNMLPDLYAEDPDFYRNMRIQDLAQGIHKLIRKHDLPGLMLRAFDTLPEMIMTPHQAW
                     QRQIKGEVETIALEQLVGRVSANMILPYPPGVPLLMPGEMLTKESRTVLDFLLMLCSV
                     GQHYPGFETDIHGAKQDEDGVYRVRVLKMAG"
     gene            38037..38426
                     /locus_tag="IRB70_001580"
     CDS             38037..38426
                     /locus_tag="IRB70_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308216.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBC0631505.1"
                     /translation="MLGLKQVHHIAIIATDYAVSKAFYCDILGFTLQSEVYREARDSW
                     KGDLALNGQYVIELFSFPFPPERPSRPEACGLRHLAFSVDDIDAAVAHLESHNVKCEA
                     IRVDPYTQKRFTFFNDPDGLPLELYEQ"
     gene            38491..39789
                     /gene="tilS"
                     /locus_tag="IRB70_001581"
     CDS             38491..39789
                     /gene="tilS"
                     /locus_tag="IRB70_001581"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBC0631506.1"
                     /translation="MTLTLNRQLLSSRQILVAFSGGLDSTVLLHQLVQWRTENPGVTL
                     RAIHVHHGLSANADAWVRHCENICQQWQVPLVVERVQLAQEGLGIEAQARQVRYQAFA
                     RTLLPGEVLVTAQHLDDQCETFLLALKRGSGPAGLSAMAEVSEFAGTRLIRPLLARTR
                     GELVQWARQYDLRWIEDESNQDDSYDRNFLRLRVVPLLQQRWPHFAEATARSAALCAE
                     QESLLDELLADDIAHCQKPQGTLQIAPMLAMSDARRAAIIRRWLAGQNAPMPSRDALV
                     RIWQEVALAREDASPCLRLGAFEIRRYQSQLWWIKSVAGQSETIVPWQTWLQPLELPA
                     GLGSVQLTAGGDIRPPRADEAVSVRFKAPGLLHIIGRNGGRKLKKIWQELGVPPWLRD
                     TTPLLFYGETLIAAAGVFVTQEGVAEGENGVSLVWQKTLS"
     gene            complement(39838..40098)
                     /gene="rof"
                     /locus_tag="IRB70_001582"
     CDS             complement(39838..40098)
                     /gene="rof"
                     /locus_tag="IRB70_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rho-binding antiterminator"
                     /protein_id="HBC0631507.1"
                     /translation="MSMNDTYQPINCDDYDNLELACQHHLMLTLELKDGEKLQGKASD
                     LVSRKNVEYLVVEAAGETRELRLDKITSFSHPEIGTVVVSES"
     gene            complement(40085..40285)
                     /locus_tag="IRB70_001583"
     CDS             complement(40085..40285)
                     /locus_tag="IRB70_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeP family protein"
                     /protein_id="HBC0631508.1"
                     /translation="MEKYCELIRKRYAEIASGDLGYVPDALGCVLKVLNEMAADDALS
                     EAVREKAAYAAANLLVSDYVNE"
     gene            40451..40996
                     /locus_tag="IRB70_001584"
     CDS             40451..40996
                     /locus_tag="IRB70_001584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeQ family protein"
                     /protein_id="HBC0631509.1"
                     /translation="MALKATIYKATVNVADLDRNQFLDASLTLARHPSETQERMMLRL
                     LAWLKYADERLQFTRGLCADDEPEAWLRNDHLGIDLWIELGLPDERRIKKACTQAAEV
                     ALFAYNSRAAQIWWQQNQSKCAQFANLSVWYLDDEQLAKVSAFADRTMTLQATIQDGV
                     IWLSDDKNNLEVNLTVWQQPS"
     gene            40993..41415
                     /gene="arfB"
                     /locus_tag="IRB70_001585"
     CDS             40993..41415
                     /gene="arfB"
                     /locus_tag="IRB70_001585"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBC0631510.1"
                     /translation="MIVISRHVAIPDGEFEITAIRAQGAGGQHVNKTSTAIHLRFDIR
                     ASSLPEYYKERLLAASHHLISSDGVIVIKAQEYRSQELNREAALARLVAVIKDLTTEQ
                     KARRPTRPTRASKERRLASKAQKSSVKAMRGKVRSGRE"
     gene            41429..42139
                     /gene="nlpE"
                     /locus_tag="IRB70_001586"
                     /gene_synonym="cutF"
     CDS             41429..42139
                     /gene="nlpE"
                     /locus_tag="IRB70_001586"
                     /gene_synonym="cutF"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591565.1"
                     /note="NlpE, an outer membrane lipoprotein, interacts
                     directly with CpxA, the sensor histidine kinase of the Cpx
                     system for response to envelope stress; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response activation lipoprotein
                     NlpE"
                     /protein_id="HBC0631511.1"
                     /translation="MVKKAIVTAMAVISLFTLMGCNNRAEVDTLSPAQAAELKPMPQS
                     WRGVLPCADCEGIETSLFLEKDGTWVMNERYLGAREEPSSFASYGTWARTADKLVLTD
                     SKGEKSYYRAKGDALEMLDREGNPIESQFNYTLEPAQSSLPMTPMTLRGMYFYMADAA
                     TFTDCATGKRFMVANNAELERGYLAARGNSEKPVLLSVEGHFTLEANPDTGAPTKVLA
                     PDTAGKFYPNHDCSSLGL"
     gene            complement(42295..43119)
                     /locus_tag="IRB70_001587"
     CDS             complement(42295..43119)
                     /locus_tag="IRB70_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaeF family permuted papain-like enzyme"
                     /protein_id="HBC0631512.1"
                     /translation="MDKPKAYCRLLLPCFLVLSACTVDISQPDSSATVVNAEAKTWAV
                     KFQHQSSFTEQSIKEITEPDLKPGDLLFSSSLGVTSFGIRVFSTSSVSHVAIYLGDNN
                     VAEATGAGVQIVSLKKAIKHSDKLFVLRVPDLTPQQATEITAFANKIKDSGYNYRGIV
                     EFIPFMVTRQMCSLNPFSEDFRQQCVSGLAKAQLSNVGEGDKKSWFCSEFVTDAFAKA
                     GHPLTLAQSGWISPADLMHMRTGDISAFKPETQLQYVGHMKPGIYIKAGRFVGLTQ"
     gene            complement(43172..44890)
                     /gene="proS"
                     /locus_tag="IRB70_001588"
     CDS             complement(43172..44890)
                     /gene="proS"
                     /locus_tag="IRB70_001588"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBC0631513.1"
                     /translation="MRTSQYLLSTLKETPADAEVISHQLMLRAGMIRKLASGLYTWLP
                     TGVRVLKKVENIVREEMNNAGAIEVLMPVVQPSELWQESGRWEQYGPELLRIADRGDR
                     PFVLGPTHEEVITDLIRNELSSYKQLPLNFYQIQTKFRDEVRPRFGVMRSREFLMKDA
                     YSFHTSQESLQETYDAMYAAYSKIFSRMGLDFRAVQADTGSIGGSASHEFQVLAQSGE
                     DDVVFSDTSDYAANIELAEAIAPKEPRAAATQEMTLIDTPNAKTIAELVEQFNLPIEK
                     TVKTLLVKAVEGSSFPLVALLVRGDHELNEVKAEKLPQVASPLTFATEEEIRAVVKAG
                     PGSLGPVNMPIPVVIDRTVAAMSDFAAGANIDGKHYFGINWDRDVATPEIADIRNVVA
                     GDPSPDGQGTLLIKRGIEVGHIFQLGTKYSEALKASVQGEDGRNQILTMGCYGIGVTR
                     VVAAAIEQNYDERGIVWPDAIAPFQVAILPMNMHKSFRVQELAEKLYSELRAQGIEVL
                     LDDRKERPGVMFADMELIGIPHTIVLGDRNLDNDDIEYKYRRNGEKQLIKTGDIVDYL
                     VKQIKG"
     gene            complement(45001..45708)
                     /gene="tsaA"
                     /locus_tag="IRB70_001589"
     CDS             complement(45001..45708)
                     /gene="tsaA"
                     /locus_tag="IRB70_001589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (N6-threonylcarbamoyladenosine(37)-N6)-methyltransferase
                     TrmO"
                     /protein_id="HBC0631514.1"
                     /translation="MSSFQFEQIGVIRSPYKEKFAVPRQPGLVKSANGELHLIAPYNQ
                     ADAVRGLEAFSHLWILFVFHQTMEGGWRPTVRPPRLGGNARMGVFATRSTFRPNPIGM
                     SLVELKEVVCHKDSVILKLGSLDLVDGTPVVDIKPYLPFAESLPDASASYAQSAPAAE
                     MAVCFTAEVEKQLLTLEKRYPQLTLFIREVLAQDPRPAYRKGEETGKTYAVWLHDFNV
                     RWRVTDAGFEVFALEPR"
     gene            complement(45705..46109)
                     /gene="rcsF"
                     /locus_tag="IRB70_001590"
     CDS             complement(45705..46109)
                     /gene="rcsF"
                     /locus_tag="IRB70_001590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rcs stress response system protein RcsF"
                     /protein_id="HBC0631515.1"
                     /translation="MRALPICLVALMLSGCSMLSRSPVEPVQSTAPQPKAEPAKPKAP
                     RATPVRIYTNAEELVGKPFRDLGEVSGDSCQASNQDSPPSIPTARKRMQINASKMKAN
                     AVLLHSCEVTSGTPGCYRQAVCIGSALNITAK"
     gene            complement(46227..47042)
                     /gene="metQ"
                     /locus_tag="IRB70_001591"
     CDS             complement(46227..47042)
                     /gene="metQ"
                     /locus_tag="IRB70_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter substrate-binding
                     lipoprotein MetQ"
                     /protein_id="HBC0631516.1"
                     /translation="MAFKFKTFAAVGALIGSLALVGCGQDEKDPNHIKVGVIVGAEQQ
                     VAEVAQKVAKDKYGLDVELVTFNDYVLPNEALSKGDIDANAFQHKPYLDQQLKDRGYK
                     LVAVGNTFVYPIAGYSKKIKSLDELQDGSQVAVPNDPTNLGRSLLLLQKVGLIKLKDG
                     VGLLPTVLDVVENPKNLKIVELEAPQLPRSLDDAQIALAVINTTYASQIGLTPAKDGI
                     FVEDKESPYVNLIVTREDNKDAENVKKFVQAYQSDEVYEAANKVFNGGAVKGW"
     gene            complement(47082..47735)
                     /gene="metI"
                     /locus_tag="IRB70_001592"
     CDS             complement(47082..47735)
                     /gene="metI"
                     /locus_tag="IRB70_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter permease MetI"
                     /protein_id="HBC0631517.1"
                     /translation="MSEPMMWLLVRGVWETLAMTFVSGFFGFVIGLPVGVLLYVTRPG
                     QIIANAKLYRTVSAIVNIFRSIPFIILLVWMIPFTRVIVGTSIGLQAAIVPLTVGAAP
                     FIARMVENALLEIPTGLIEASRAMGATPMQIVRKVLLPEALPGLVNAATITLITLVGY
                     SAMGGAVGAGGLGQIGYQYGYIGYNATVMNTVLVLLVILVYLIQFAGDRIVRAVTRK"
     gene            complement(47728..48759)
                     /gene="metN"
                     /locus_tag="IRB70_001593"
     CDS             complement(47728..48759)
                     /gene="metN"
                     /locus_tag="IRB70_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014168731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine ABC transporter ATP-binding protein
                     MetN"
                     /protein_id="HBC0631518.1"
                     /translation="MIKLSNITKVFHQGTRTIQALNNVSLHVPAGQIYGVIGASGAGK
                     STLIRCVNLLERPTEGSVLVDGQELTTLSESELTKARRQIGMIFQHFNLLSSRTVFGN
                     VALPLELDNTPKDEIKRRVTELLSLVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK
                     VLLCDEATSALDPATTRSILELLKDINRRLGLTILLITHEMDVVKRICDCVAVISNGE
                     LIEQDTVSEVFSHPKTPLAQKFIQSTLHLDIPEDYQERLQAEPFADCVPMLRLEFTGQ
                     SVDAPLLSETARRFNVNNNIISAQMDYAGGVKFGIMLTEMHGTQQDTQAAIAWLQEHH
                     VKVEVLGYV"
     gene            48947..49519
                     /gene="gmhB"
                     /locus_tag="IRB70_001594"
     CDS             48947..49519
                     /gene="gmhB"
                     /locus_tag="IRB70_001594"
                     /EC_number="3.1.3.82"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-glycero-beta-D-manno-heptose 1,7-bisphosphate
                     7-phosphatase"
                     /protein_id="HBC0631519.1"
                     /translation="MAKSVPAIFLDRDGTINVDHGYVHEIDNFEFIDGVIDAMRELKK
                     MGFALVVVTNQSGIARGKFTEAQFETLTEWMDWSLADRDVDLDGIYYCPHHPQGSVEE
                     FRQVCDCRKPHPGMLLSARDYLHIDMAASYMVGDKLEDMQAAAAANVGTKVLVRTGKP
                     VTPEAENAADWVLNSLADLPQAIKKQQKPA"
BASE COUNT        11988 a        12284 c        13480 g        11968 t
ORIGIN      
        1 aacggtcctg atctgtaggt cggataaggc gtttacgccg catccgacaa accatgctgg
       61 atcacaactt cgcaaacacc cgacgtgcag catcgatggt gttattgata tcttccatgc
      121 tgtgcgctac agacataaag cccgcttcaa acgctgatgg tgccaggtaa acaccttcat
      181 ccagcatcat atggaagaaa cgcttaaagc gttccacgtc acaggccatt acatcctgat
      241 agcacgtcac ggactcggcg tcggtaaaga aaataccgaa catgccgcca acgtggttaa
      301 cgaccagcgg aattccggct tcttctgccg cttccagcag gccttctgcc agacgtgttg
      361 tcagctcatc cagcgtttcg tgaacgcccg gctgtgcgac ttcattcaga caggcgaaac
      421 cggccgccat cgcaatcggg ttaccggaaa gcgtacccgc ctgatagacc ggaccagtcg
      481 gggccagcgc atccattaca tcacgacgac caccgaatgc gcctaccggc attccaccgc
      541 cgatgatttt gccgaggcag gttaaatctg gcactacgcc gtaataatcc tgtgcgccag
      601 ctagcgctac gcggaaaccg gtcatcactt catcgatgat cagcaacgcg ccaaattcgt
      661 cacacagcgc acgcagacct ggcaggaact ctggcagcgg cggaacacag ttcatattgc
      721 ctgccaccgg ctcgacgata atacaggcaa tctcttgcgg gtattgctca aacgcggcgc
      781 gtacagaagc cagatcgtta taagtacagg ttaaggtatg tttggcgaaa tctgccggaa
      841 cgcccggcga atttggctgg cctaacgtga gtgcgccaga accggctttc accagcaggc
      901 agtcagcgtg accgtggtaa caaccttcaa atttaatgat tttgtcgcga ccggtaaaac
      961 cacgggccag gcggatggcg ctcatcgtcg cttcagtgcc ggagttcacc atgcgcacca
     1021 tatccatggt cgggaccagt tcggtcacca gttgcgccat tttcacttcc atttcggttg
     1081 gtgcaccaaa gcttaaacca cgctcggcgg cttcaatcac ggcattgcgg atcgccggat
     1141 ggttatggcc cagcaccatc ggcccccagg aaccgacata atcgatatag gctttgccat
     1201 caacatcgta cagataagcg ccgtccgctt tttcgataaa cagtggagtg ccgcccacgc
     1261 cagtaaaggc gcgaacaggg gagttcacac cgccagggat cagctcgcgc gctgcgctgt
     1321 aaagattttc agacttactc atggagggtt cctgattcgt agaaaaagtg aatggctgct
     1381 attctatgtt attcataaca agttaaatac tcgtcaaaca tcaggctgct tgtactggtg
     1441 caatcctgat ttcttagagt ataaaagttt tgtgcatttg aaacattacg ctttgcaaag
     1501 gattttcatg gaacgtgcga gtaaaatgcc gtcatcttat ttgtatgacc aataagtgat
     1561 cattggatga aaactgatac tccctcttta gaaacaccgc aggccgcgcg cctgcgacgc
     1621 agacaactga ttcgccaact tcttgagcgc gataaaaccc cgttagccat tttgtttatg
     1681 gcggcagtcg tcggcacgct tgtcgggctg gctgcggttg cttttgacaa aggtgtcgcc
     1741 tggttgcaga accaacgtat gggggcactg gtacatactg ctgataatta tccgctactg
     1801 ttaaccgtcg cttttctctg ttcggcggtg ctggcgatgt tcggctactt tttggtgcgc
     1861 aaatatgcgc cggaagcagg tggttcgggg atcccggaaa ttgaaggggc gctggaagat
     1921 caacgtcccg ttcgctggtg gcgtgtgttg ccggtgaaat tctttggcgg gctgggaaca
     1981 cttggcggag gcatggtgtt ggggcgcgaa gggccaaccg tgcagatagg cggcaatatc
     2041 gggcggatgg tactcgatgt tttccgcctg aaaggtgacg aagctcgtca tacgctactg
     2101 gcaaccggtg ctgctgcggg gctggctgcg gcctttaacg cgccgctggc gggtattttg
     2161 tttattatcg aagagatgcg tccgcagttt cgctatacgt taatttcgat taaagcggta
     2221 tttattggcg tcattatgtc gaccattatg taccggattt ttaatcatga agttgcgttg
     2281 attgacgtcg gtaaactttc tgatgcgccg cttaatacgc tgtggcttta tctgatcctc
     2341 ggtattattt ttggcatttt cggccctatt tttaataaat gggtgctggg gatgcaggat
     2401 ttgctgcacc gtgtgcacgg tggcaatatt accaaatggg tactgatggg cggtgcgatt
     2461 ggcggtctgt gtggattgct ggggtttgtg gcaccagcaa cgtcgggcgg cggttttaac
     2521 ctgattccta tcgctaccgc ggggaatttc agcatgggaa tgctggtgtt tatcttcgtc
     2581 gcgcgggtca ttaccacctt actctgcttc tcttccggcg cgccgggcgg tatttttgcc
     2641 ccgatgctgg cgctgggtac tgtgctggga accgctttcg gaatggttgc cgttgagctg
     2701 tttccgcaat atcaccttga ggcggggacg tttgctattg ccggaatggg ggcgttactg
     2761 gcggcatcta ttcgcgcgcc gttaacgggg atcattctgg ttctggagat gaccgataac
     2821 taccagctca ttttgcctat gattattacc ggtcttggcg caacactatt agcgcaattt
     2881 accggcggga aaccgctata ctcggcgatt cttgcgcgca cgctggcaaa acaggaagct
     2941 gagcaactgg cgcgaagcaa ggccgcatca gccagcgaga atacttgaac gaaataccag
     3001 ggtattagat aatggcgatt attattgggt tagaatttgc ccaattgccg atgtcgtttg
     3061 gagcaaaata tgagtgatga cgtagcactg ccgctggagt ttaccgacgc agcagccaac
     3121 aaagttaaaa gcctgatcgc tgacgaagat aacccgaatc tgaaattacg cgtgtatatc
     3181 accggtggcg gttgcagcgg cttccagtat ggtttcacct ttgatgatca ggtgaacgaa
     3241 ggcgatatga ccatcgaaaa acagggcgtt ggcctggtgg ttgatccgat gagcctgcaa
     3301 tatctggtcg gcggttccgt tgactatacc gaaggactgg aaggttctcg tttcatcgtg
     3361 accaacccga acgcgaaaag cacctgcggt tgcggttctt cctttagcat ctaatctgtt
     3421 gttcatgtgc cggataaact atccggcaca tcttctctct tcaacgccca ttctcatcca
     3481 gcgcaaacgt cggtagctta agatgccaac gaatagccgc cagccgaatc aatagcgtca
     3541 cgaccatgcc catcatactg gctgtttcca gtggtacgga aaatgtgtaa taagccgtag
     3601 cgtggacaat accgccgata atacaggctg ttgcgtagat ttctgtacgt aaaatcatgg
     3661 ggatttcgcg ggccagtaca tcacgaatga tcccgccgcc aacgccagta atgacgccca
     3721 tacaaaccgc gattaacgga ccggcttccg cattaaaggc tttattcacg ccaatgccga
     3781 caaacaccgc cagaccaacg gcgtccagca ccggcaacat ccattttggt aagcgtcttg
     3841 gctggcgcac cagcacgatg gtcagcatgc tggtgaccat tgcaacgacc agatcggtgg
     3901 gatctttcac ccaaaatacc gggccgtgat ccagcgccat gtcgcgaatt gttccgccgc
     3961 ctactgcggt aaccacgccc aataccagta caccaaaagg gtccatacgc aattttccgg
     4021 ctaacaaaac gccagagata gcaaataccg ctgtgccgac tatatccagc caatagacga
     4081 gcattgttca atccccactg agcacctgaa aaggtcaggc actaatctac ctgtgaaagc
     4141 gcattacaga gctgttgtgc agcgaggata atacgtgggc ttgcacgttc aaaccagtca
     4201 ctcgtgagag gaataacggg aattttgagc tgttcacccc agtattgttt gattttagga
     4261 atttggtccg atccgcctgt aatgacaatc gcctgtggcg agcgtgctaa cacctgttca
     4321 cggctaactt gcggccaggg aacccggctg tctttaaaga tgttttctcc gccacaaact
     4381 tcgagtacct ggttttgaat cgactctttt ccactggtaa atggcggatt aatgccgaat
     4441 tgcagaaaaa cacgtttttt aggtttatca gcatattgcg ctttcaattg cgcgtactga
     4501 tccagcaggg attgcgcggc ttgttcggcc ttatccggtt gcggactcca gggggccagt
     4561 tgacgtaacg cattggcaat ttgttcaatg cttgtcgcat cgacccacat cacttttatt
     4621 cccagcgaag ccagctggtc aacctgccgc tcggcattac ctccacgcca ggcaatcacc
     4681 agatcgggtt tcagcgcgac aatgcgttcc agattcatcc cctgccaggt ggaaacctgc
     4741 tcaatctttt gcgcttgtgg aggatagtcg gaatagctgc tgaccccaac cggcgtgatc
     4801 ccggcggcaa aggcaagttc agtgttggcg ggagaaagcg tgatgacgcg cggcgcggca
     4861 ttgagccaca gcggcgcgag aaaagacagg gcgaccagcg ccctgaacag tgacttagcc
     4921 atgtgccagt ttctgcacca gtgactcaac catcaggctg gactgtttag cggcaacagc
     4981 caggaactca tcgaagctaa gatgagactg ttgatcggcc acgtcggaga tggcgcgtac
     5041 tacgacaaac gggacgttga aattgtggca gacatgggcg attgccgtcg cttccatctc
     5101 tacagcaatg gcctgtggga agttgtggcg gattttcgcc agaccaacag aaccgttgat
     5161 gaatgcgtcg ccgctaacaa tcaggccacg tacagcgtta agattcagtt cggcaatgca
     5221 ggcctcagcg gcagcgatca gtttatcgtc agctttaaag cctgccgggc agcctggtaa
     5281 ctggccgtat tcataaccaa atgccgtgac atccgcgtcg tgataacgag cttcgtccga
     5341 gacaacgata tcgcccactt tcagcgttgg tgccaggcca ccggcagaac cggtgttaat
     5401 aatcacatct ggcttgcagt gttccaacag cagagtggca cccagcgccg cagcgacttt
     5461 accgatgccc gatttcagaa gcgcaacctc ggttccattc agttggccgg tatagatttc
     5521 gcaaccgccc agactgatag tttgacggtt ttcgattttg tcacgcagca gcgtaacttc
     5581 ttcttccatt gcaccaatga tgccgatttt catagattta ctcgcgataa gcccgatttg
     5641 aaggcatagt ttaccatgcg cttacgggga agcgtatttc tcacgcggga gaggacatgg
     5701 cacagattga tttccgaaaa aaaataaact ggcatcgtcg ttaccgttca ccacagggcg
     5761 ttaaaaccga acatgagatc ctgcggatct tcgagagcga tcgcgggcgt atcatcaact
     5821 ctccggcaat tcgtcgtctg caacaaaaga cccaggtttt tccactggag cgcaatgccg
     5881 ccgtgcgcac gcgtcttacc cactcgatgg aagtccagca ggtggggcgt tatatcgcta
     5941 aagagatttt aagccgcctg aaagagctta aattactgga ggcgtatggt ctcgatgaac
     6001 tgaccgggcc ctttgaaagc attgttgaga tgtcatgcct gatgcacgat atcggcaatc
     6061 cgccgtttgg tcattttggc gaagcggcga taaatgactg gtttcgccag cgtttgcacc
     6121 cggaagatgc cgaaagccag cctctgactg acgatcgctg cagcgtggca gcactacgtt
     6181 tacgggacgg ggaagaaccg cttaacgagc tgcggcgcaa aatacgtcag gacttatgtc
     6241 attttgaggg gaatgcacaa ggcattcgtc tggtgcatac attgatgcgg atgaatctca
     6301 cctgggcgca ggttggcggt attttaaaat atacccgtcc agcgtggtgg cgtggcgaaa
     6361 cgcctgagac acatcactat ttaatgaaaa agccgggtta ttatctttct gaagaagcct
     6421 atattgcccg gttgcgtaaa gaacttaatt tggcgcttta cagtcgtttt ccattaacgt
     6481 ggattatgga agctgccgac gacatctcct attgtgtggc agaccttgaa gatgcggtag
     6541 agaaaaggat atttaccgtt gagcagcttt atcatcattt gcacgaggcg tggggccagc
     6601 atgagaaagg ttcgctcttt tcgctggtgg ttgaaaatgc ctgggaaaaa tcacgctcaa
     6661 atagtttaag ccgcagtacg gaagaccagt tttttatgta tttacgggta aacactctaa
     6721 ataaactggt accctacgcg gcacaacgat ttattgataa tctgcctgcg attttcgccg
     6781 gaacgtttaa tcatgcatta ttggaagatg ccagcgaatg cagcgatctt cttaagcttt
     6841 ataaaaatgt cgctgtaaaa catgtgttta gccatccaga tgtcgagcag cttgaattgc
     6901 agggctatcg ggtcattagc ggattattag agatttatcg ccctttatta agcctgtcgt
     6961 tatcagactt tactgaactg gtagaaaaag aacgggtgaa acgtttccct attgaatcgc
     7021 gcttattcca caaactctcg acgcgccatc ggctggccta tgtcgaggct gtcagtaaat
     7081 taccgtcaga ttctcctgag tttccgctat gggaatatta ttaccgttgc cgcctgctgc
     7141 aggattatat cagcggtatg accgacctct atgcgtggga tgaataccga cgtctgatgg
     7201 ccgtagaaca ataaccaggc ttttgtaaag acgaacaata aatttttacc ttttgcagaa
     7261 actttagttc ggaacttcgc gctataaaac gaatctgaag aacacagcaa ttttgcgtta
     7321 tctgttaatc gagactgaaa tacatgaaaa aaaccacatt agcactgagt gcactggctc
     7381 tgagtttagg tttggcgtta tctccgctct ctgcaacggc ggctgagact tcttcagcaa
     7441 cgacagccca gcagatgcca agccttgcac cgatgctcga aaaggtgatg ccttcagtgg
     7501 tcagcattaa cgtagaaggt agcacaaccg ttaatacgcc gcgtatgccg cgtaatttcc
     7561 agcagttctt cggtgatgat tctccgttct gccaggaagg ttctccgttc cagagttctc
     7621 cgttctgcca gggtggccag ggcggtaatg gtggcggcca gcaacagaaa ttcatggcgc
     7681 tgggttccgg cgtcatcatt gatgccgata aaggctatgt cgtcaccaac aaccacgttg
     7741 ttgataacgc gacggtgatt aaagtccaac tgagcgatgg ccgtaagttc gacgcgaaga
     7801 tggttggcaa agatccgcgc tctgatatcg cgctgatcca gatccagaac ccgaaaaacc
     7861 tgaccgcaat taagatggcg gattctgatg cactgcgcgt gggtgattac accgtagcga
     7921 ttggtaaccc gtttggtctg ggcgagacgg taacttccgg gattgtctct gcgctggggc
     7981 gtagcggcct gaatgccgaa aactacgaaa acttcatcca gaccgatgca gcgattaacc
     8041 gtggtaactc cggtggtgcg ctggttaacc tgaacggtga actgatcggt atcaacaccg
     8101 cgatcctcgc accggacggc ggcaacatcg gtatcggttt tgctatcccg agcaacatgg
     8161 tgaaaaacct gacctcgcag atggtggaat acggccaggt gaaacgcggt gagttgggta
     8221 ttatgggcac tgagctgaac tccgatctgg cgaaagcgat gaaagttgac gcccagcgcg
     8281 gtgctttcgt aagccaggtt ctgccgaatt cttccgccgc gaaagcgggc attaaagcgg
     8341 gtgatgtgat cacctcactg aacggtaagc caatcagcag ctttgccgca ctgcgtgctc
     8401 aggtgggcac tatgccggta ggtagcaaac tgaccctggg cttattgcgc gacgggaagc
     8461 aggttaacgt gaacctggaa cttcagcaga gcagccagaa tcaggttgat tccagcacca
     8521 tcttcaacgg cattgaaggc gctgagatga gcaacaaagg caaagatcag ggcgtggtag
     8581 tgaacaacgt gaaaacgggc actccggctg cgcagatcgg cctgaagaaa ggtgatgtga
     8641 ttattggcgc gaaccagcag gcagtgaaaa acatcgctga actgcgtaaa gttctcgaca
     8701 gcaaaccgtc tgtgctggca ctgaacattc agcgcggcga cagcaccatc tacctgttaa
     8761 tgcagtaatc tccctcaacc ccttcctgaa aacgggaagg ggttctcctt acaatctgtg
     8821 aacttcacca caactccata catcttcatc atcctttggg catttgcaca atgccgtacg
     8881 ttacgtactt ccttatgcta agccgtgcat aacggaggac ttatggctgg ctggcatctt
     8941 gataccaaaa tggcgcagga tatcgtggca cgtaccatgc gcatcatcga taccaatatc
     9001 aacgtaatgg atgcccgcgg gcgaattatc ggcagcggcg atcgtgagcg tattggtgaa
     9061 ttgcacgaag gagcattgct ggtactttca cagggacgag tcgtcgatat cgatgacgcg
     9121 gtggcacgtc atctgcacgg tgtgcggcag gggattaatc taccgttacg gctggaaggt
     9181 gaaattgtcg gcgtaattgg cctgacaggt gaaccagaga atctgcgtaa atatggcgaa
     9241 ctggtctgca tgacggctga aatgatgctg gaacagtcgc ggttgatgca cttgttggcg
     9301 caggatagcc gtttgcggga ggaactggtg atgaacctga ttcaggcaga ggagaatact
     9361 cccgcactta ctgaatgggc gcaacggctg gggatcgatc tcaatcaacc gcgagtggtg
     9421 gctattgttg aggtcgacag cggtcagctt ggtgtggaca gcgcaatggc ggagttacaa
     9481 caactgcaaa acgcgctgac tacgcccgag cgtaataatc tggtggcgat tgtctcgcta
     9541 accgaaatgg tggtgttgaa accggcgttg aactcttttg ggcgctggga tgcagaagat
     9601 catcgtaagc gagttgaaca actgattacc cgcatgaaag agtacggcca gctgcgtttt
     9661 cgcgtttcac tgggcaacta ttttaccggt cctggcagta ttgcccgatc ctatcgtacg
     9721 gcgaaaacga cgatggtggt gggtaaacag cgaatgccag aaagtcgctg ctatttttat
     9781 caggatctga tgttgcctgt gttactcgac agtttgcgtg gcgactggca ggccaacgaa
     9841 ctggcgcgac cgctggcgcg gctgaaagcg atggacaata acggcttgct gcggcgaacg
     9901 ctggcggcgt ggtttcgcca caatgtgcaa ccgctggcaa cgtcaaaggc gttgtttatt
     9961 catcgtaata ctctggaata tcggcttaat cgtatatcgg aactgaccgg gcttgatttg
    10021 ggcaattttg atgacaggtt gctgctgtat gtggcgttac aactggatga agagcggtag
    10081 gtcgattaca aaattacagc cgggtgagac tttacccggc ccacagaatg acattattta
    10141 cgcgtcagtt tttccagatc ggcttcaatc tcgctgatct tattggttac tactgactcc
    10201 aggtgacgta agtcgtcgag gatcttacgc ttaagatcaa cttcgctgcg gtcacgctgg
    10261 cagatttgat caagctcatc aatgatatac cgtagattcg ggctgatttc ctggacttct
    10321 ttataaccct gacccacacc atcagcgacg accgttttac gctgacgcgg atatttaaac
    10381 ttcacgctct tggcgaaaaa ctcgcctttg tctttctgga aatagatttt cagaatatcg
    10441 ttgttggctt cctgccggag gctgtaacga tcaatttctt caggattggt aatacccaga
    10501 cttttcagat tgtcgtacat agcgttacct caaaatgagt cagtaaattg tgcttatttt
    10561 agcatttggc ctggcccgcc cggctcgact gtgatcgcag aaagcctttt tcttccagac
    10621 ttctatcatg gcgtaaaaat caaaaaatta cctgctttat tgtggcgata aaattcacgt
    10681 tctacaccag ttccagcatc gttacttccg ggcggctgtt cagacgcaaa ccatacaaac
    10741 tgcccacgcc acgggttgtg tagatgtgtc gttcgccaaa ggcatttaat ccggcgacgt
    10801 aacgtttatc ttcgacaggg gcaaaaggtt caccaaccaa cggtacgcgc agttgcccgc
    10861 cgtgagtatg gccgcacagc atcagatccc agggatcatc acgcatgact tctttgctgt
    10921 caggattatg cgccagcacc agtcttggca gattggcttc gctggcggga ggcggtttgc
    10981 attgtccggc ccataagtca ccggtgccta ccagttcgaa ttgcctgttc ggcgtggcga
    11041 tcaccgtagc ctggttaaac aacaccgtga tgcccactga tttcaacgtc tcgccaatta
    11101 agtgattttt ttctgtacca acagggcgat cgtggttgcc gaagcaggca aacgtcggcg
    11161 cacattcggc aaggggggag agtacgtcac taaacgccga aaaattcagc ggcatatcaa
    11221 ataatacgta atcgccgccc agtaatatca aatcgggctt ttgttctatg ccaagagcaa
    11281 tcgcgtcaga aatcaggctt aaaggaacaa aacgagagta atggagatcg gccagaaaaa
    11341 gaattttgaa tggtgctgcg ttgtctttaa aaaaggcgag gcggtgacgg attaattcaa
    11401 accagcctgg ctccctgtaa tgcatataac tgaaacctga gcccgtggct atcgtcgcgg
    11461 cagtagcctg caaaaatcgg cggcgtgaaa tcatcgctca tccctgcaaa aaaatcgggc
    11521 agcgtcgtgc tgcccgtgta catactttta gtcgatggta cgcagcagtt cgttaatgcc
    11581 gactttgccg cgagttttcg cgtcaacttt cttaacgata accgcacagt aaagactgta
    11641 tttgccatct ttcgacggca gattgcctga aacaaccaca gatcccgccg gaacgcgacc
    11701 gtagtggatt tcgccggttt cacggtcgta aatacgggtg ctctgaccaa tgtatacgcc
    11761 catagagatg acggaacctt cttcgacaat caccccttca accacttcag agcgtgcgcc
    11821 gatgaagcag ttatcttcaa taatggtcgg gttagcctgc agcggctcca gcacgccgcc
    11881 gatacccacg ccaccggaaa ggtggacgtt tttaccaatc tgcgcacagg aaccgacggt
    11941 cgcccaggta tcaaccatgg tgccttcatc aacatatgcg ccgatgttga cgtaagacgg
    12001 catcagcacg gtgttacggg caatgaacgc gccctgacgc actgccgctg gtggcacgac
    12061 gcggaagcct tctttctgga aacgtgcttc atcgtagtta gcgaatttca tcggcacttt
    12121 gtcgaagtag cggctttctg ccccttcgat cacctgatta tcattaatac ggaaagagag
    12181 cagcaccgct tttttcaacc actgatgcgt cacccactga ccgtcaattt tttccgctac
    12241 acgcagtgcg ccggaatcca gcagggcgat cacctgattt accgcttcgc gggtaacggt
    12301 gtctgcattg gctggcgtga tctcggcacg gcgttcaaaa gcggtttcaa taatgttctg
    12361 taactgctgc attgttaaac tcttttcata tcagtaaaca catcaccctt tatcgtttgg
    12421 attgagggcc tctgtcaacc gctgatgcac ttcctgctgc aactcgttat taagcgcacg
    12481 ccggtcagcg gtggcaatta tgaataaatc ttctactcgc tcgccaatgg ttgtaattcg
    12541 ggcgccatga agcgaaattc ccagatcggc aaaaattttc ccgactcgcg ccagcagacc
    12601 tggttggtcg agggcgatca gttcgaggaa cgatttgcgg tcggtatggg tcggcaaaaa
    12661 cgtcacttcg gtttcaacag taaaatggcg caatttggca ggttggcgac ggggctgcgg
    12721 tggctgccag ctactttgtg tcagcacctg ctccagacca aaccgaataa cctcatggcg
    12781 atctgcggac agcgggctgc catcgggttc cagcactata aaggtatcca tcgccatacc
    12841 gtcgcgagtg gtgaaaattt gtgcgtcgtg aacacttaaa ttgcggcggt ctaattcggc
    12901 acagacggcg gcaaacagat aggggcggtc cgggctccag ataaaaatct cggtgcctcc
    12961 acgcgtagcc tgcgggctaa gcagtaccag cggtttgctt aaatcatgct gtaataaatg
    13021 gcgtgcgtgc caggccagtt gatttgggct atggcggaca aaatagttag cgcgacagcg
    13081 tgaccaaatt tggtgcagcg cctcttcgtc gatgttatcc atgcgcagta gtgccagcgc
    13141 ctggagttgg tgatggcgaa cccgttcgcg catatccggc gtgttttgca ttccgcgtcg
    13201 tagctgcttt tcggtggcga aatagagttc gcgcaacaga ctttgcttcc agctattcca
    13261 cagtgtttcg ttggtggcgc aaatgtcagc cactgtcagg cataccagat agcgcagacg
    13321 attttccgtt tgaacttctt cggcaaactg cttgatgact tccgggtcct gaatatcgcg
    13381 gcgctgagct gtcaccgaca tcagcaagtg ctggcgaacc agccaggcga ccaactgtgt
    13441 ttcgcgggag ttcagcccgt ggagttcggc aaaatgcact acatcctgag caccgagaat
    13501 ggagtggtcg ccgccgcgtc ctttggcgat atcgtgaaac agcgcggcga tgaaaatcag
    13561 ctcagttgac ggcaggcgcg gccagacgtc cacacacaat ggatggcgct ggcgcgtttc
    13621 ttcactggca aaactctcca gtttcaacat cacgcggata gtatgttcat ccaccgtgta
    13681 ggcgtggaac agatcaaact gcatctgccc gacgatatgc gaccattgcg gcatatacgc
    13741 gccgagcacg ctatggcgat gcattggcaa tagcccgcgc cgcaccgctc cggggtgacg
    13801 aagaatgctc aaaaacagtt ttcgcgcttc cggaatatta cacagaggtt gttgcaggtg
    13861 gcgacgggca tggcgtaact ggcgcagcgt ggtggagtaa atgccggtga tcgcactgtt
    13921 gcgcaccatg gtgtagaaca tacgcaagat ggcttctggc tggcgcataa atagtgtttc
    13981 atcacgcagg tcgatcagcg ttccgcgtag ctgaaactca tcgtcgattg gacgtggttt
    14041 ttcgtcggcg ggaagggcga ggatggcttc atcgaacagt tgcagcagca tctggttgag
    14101 ttcactgacg cggcgtgtaa cgcggaagta atccttcatc atccgctcga ccggttcgtt
    14161 accttcacca ctgtaattca aacgctgggc gacgctaagc tggcgatcga ataacaggcg
    14221 attatcgtaa cgactgacga ccagatgcag ggcaaagcga atgcgccaca atatatgcag
    14281 gcattcgttt aattccgctc gctccgcaga ggttaagaag ccaaacccta ccatttcatc
    14341 cagcgatgtt gcgccaaaat gacggcgggc cacccattgc agagtgtgga tatcgcgcaa
    14401 gccgccgggg ctacttttga tgtctggttc aaggttgtag ctggtgccgt ggtaacgctg
    14461 atggcgctgg ttctgttctt caactttcgc cgcgtagaac ttgtcggaag gccagaatcc
    14521 ttcgctaaaa atatgttttt gcagttcgag gaacagcgca acatcgccaa ttaataagcg
    14581 ggattcgatt aaattggtgg cgacggttaa atccgataac ccttccagca tgcactcttc
    14641 aagcgtgcgc acgctatgac ccacttccag ctttacatcc cagagcagcg ttaacagctc
    14701 gcccactttt tgcgcctgat cgtccgggag ctttttacgg cttaaaatca gtaaatcgat
    14761 gtcagaaagt ggatgcagct cgccacgacc gtagccaccg acggcgacca atgccaggtc
    14821 ggcaatctgg ctgaatcccg cttcaatcca taaccgttgc aggagctggt cgataaactc
    14881 ggtacgcgcc tcaatcaact cttctgcaga gattccattg tcaaaggcat cacccagcca
    14941 acgctggaaa gtatcaatat gggcttttat cccacaaacg gttaattcat cactgggcca
    15001 ggcgcatgga ttttgcggtt gaccgggcag ggtggggaga gcggtgtttg cgtactgttc
    15061 tggaagggta ttcattgtgc gccacccata agattaaatt atcgcattaa aaaagccggc
    15121 attcgccggc ttcatcttat tcgtcgtgcg agattatcgc cgggatggtg tcatccttgc
    15181 gtagcgtcag aatttcgcag ccgttatcag tcaccacaat agtatgctcg tattgtgcag
    15241 acaagctgcg atctttggtt tttaccgtcc agccatcttt catggtgcgg atctcttttt
    15301 tacccgcgtt gaccattggc tcaatggtga aggtcattcc cggtttcagc acgacgttgg
    15361 tttcacggga gtcatagtgc agcacctgcg gttcttcatg gaagccgcga ccaataccgt
    15421 gtccgcaata ttcacgaacg acggagaagc cttctgcttc gacaaatttc tgaattgccg
    15481 caccgatttc gcgcagatta atgccaggtt ttaccatgcg tagcgccagg tacaggcttt
    15541 cttgcgtgat gcggcacaga cgttcgccca tgatggtcgg cttaccgacg ataaacattt
    15601 tcgaggtatc gccgtggaaa ccatctttga ttacggtgac atcaatgtta acgatatcgc
    15661 catctttcag cagcttcgca tcgtccggga tgccgtggca caccacttca ttaatagaga
    15721 tgcagacgga tttcggatag ccgtgatagc cgaggcaggc agaaaccgcg tgttgttcat
    15781 taacaatgta atcattacag atgcgatcca gctcgccggt gctgacgccc ggtttaacat
    15841 acggttcgat catctccagc acttcggcag ccagtcggcc agcgacgcgc attttttcga
    15901 tatcttctgg ggtcttgatt gagatagcca ttaattctgt ccatcagcgt cggtgatacc
    15961 gacaatatat atgtaagtgc cgtcaatggt atcacacccg ggcaaattga gaatcattct
    16021 gaatttcgcc aaacgtgcca ctgaaggttt tctataatag aaaattcaac gtctgatgct
    16081 gtacacagcg ccaacaatta ttggtgtcca cgacgtattt gtggtataaa gcgcgccgga
    16141 cttccgatcc atttcgtata cacagactgg acggaagcga caatctcact ttgtgtaaca
    16201 acacacacgt atcggcacat attccggggt gccctttggg gtcggtaata tgggatacgt
    16261 ggaggcataa ccccaacttt tatatagagg ttttaatcat ggcaactgtt tccatgcgcg
    16321 acatgctcaa ggctggtgtt cacttcggtc accagacccg ttactggaac ccgaaaatga
    16381 agccgttcat cttcggtgcg cgtaacaaag ttcacatcat caaccttgag aaaactgtac
    16441 cgatgttcaa cgaagctctg gctgaactga acaagattgc ttctcgcaaa ggtaaaatcc
    16501 ttttcgttgg tactaaacgc gctgcaagcg aagcggtgaa agacgctgct ctgagctgcg
    16561 accagttctt cgtgaaccat cgctggctgg gcggtatgct gactaactgg aaaaccgttc
    16621 gtcagtccat caaacgtctg aaagacctgg aaactcagtc tcaggacggt actttcgaca
    16681 agctgaccaa gaaagaagcg ctgatgcgca ctcgtgagct ggagaaactg gaaaacagcc
    16741 tgggcggtat taaagacatg ggcggtctgc cggacgctct gtttgtaatc gatgctgacc
    16801 acgaacacat tgctatcaaa gaagcaaaca acctgggtat tccagtattt gctatcgttg
    16861 ataccaactc tgatccggac ggtgttgact tcgttatccc gggtaacgac gacgcaatcc
    16921 gtgctgtgac cctgtacctg ggcgctgttg ctgcaaccgt acgtgaaggc cgttctcagg
    16981 atctggcttc ccaggcggaa gaaagcttcg tagaagctga gtaataaggc acgctcgtac
    17041 gagcccttat agaccaggta gtacacgttt ggttaggggg cctgcatatg gccccctttt
    17101 tcacttttat atctgtgcgg tttaatgccg ggcagatcac atctccgagg attttagaat
    17161 ggctgaaatt accgcatccc tggtaaaaga gctgcgtgag cgtactggcg caggcatgat
    17221 ggattgcaaa aaagcactga ctgaagctaa cggcgacatc gagctggcaa tcgaaaacat
    17281 gcgtaagtcc ggtgctatta aagcagcgaa aaaagcaggc aacgttgctg ctgacggcgt
    17341 gatcaaaacc aaaatcgacg gcaactacgg catcattctg gaagttaact gccagactga
    17401 cttcgttgca aaagacgctg gtttccaggc gttcgcagac aaagttctgg acgcagctgt
    17461 tgctggcaaa atcactgacg ttgaagttct gaaagcacag tttgaagaag aacgtgttgc
    17521 gctggtagcg aaaattggtg aaaacatcaa catccgccgc gttgctgcgc tggaaggcga
    17581 cgttctgggt tcttatcagc acggtgcgcg tatcggcgtt ctggttgctg ctaaaggcgc
    17641 tgacgaagag ctggttaaac acatcgctat gcacgttgct gcaagcaagc cagaattcat
    17701 caaaccagaa gacgtatccg ctgaagtggt agaaaaagaa taccaggtac agctggatat
    17761 cgcgatgcag tctggtaagc cgaaagaaat cgcagagaaa atggttgaag gccgcatgaa
    17821 gaaattcacc ggcgaagttt ctctgaccgg tcagccgttc gttatggaac caagcaaaac
    17881 tgttggtcag ctgctgaaag agcataacgc tgaagtgact ggcttcatcc gcttcgaagt
    17941 gggtgaaggc atcgagaaag ttgagactga ctttgcagca gaagttgctg cgatgtccaa
    18001 gcagtcttaa ttatcgaaaa ggagccgcct gagggcggct tctttttgtg cccatcttgt
    18061 aaattcagct aacccttgtg gggctgcgct gaaaagcgac gtacaatgtc gctagtatta
    18121 attcatttca atcgttgaca gtctcaggaa agaaacatgg ctaccaatgc aaaacccgtc
    18181 tataaacgca ttctgcttaa gttgagtggc gaagctctgc agggcactga aggcttcggt
    18241 attgatgcaa gcatactgga tcgcatggct caggaaatca aagaacttgt tgaactgggc
    18301 attcaggttg gtgtggtgat tggtgggggt aacctgttcc gtggcgctgg tctggcgaaa
    18361 gcgggtatga accgcgttgt gggcgaccac atggggatgc tggcgaccgt aatgaacggc
    18421 ctggcaatgc gtgatgcact gcaccgcgcc tatgtgaacg ctcgtctgat gtccgctatt
    18481 ccattgaatg gcgtgtgcga cagctacagc tgggcagaag ctatcagcct gttgcgcaac
    18541 aatcgtgtgg tgatcctctc cgccggtaca ggtaacccgt tctttaccac cgactcagca
    18601 gcttgcctgc gtggtatcga aattgaagcc gatgtggtgc tgaaagcaac caaagttgac
    18661 ggcgtgttta ccgctgatcc ggcgaaagat ccaaccgcaa ccatgtacga gcaactgact
    18721 tacagcgaag tgctggaaaa agagctgaaa gtcatggacc tggcggcctt cacgctggct
    18781 cgtgaccata aattaccgat tcgtgttttc aacatgaaca aaccgggtgc gctgcgccgt
    18841 gtggtaatgg gtgaaaaaga agggacttta atcacggaat aattcccgtg atggataaat
    18901 aagggtaaga ttccgcgtaa gtatcgcggg ggatcttacc cgtaatatgt ttaatcaggg
    18961 ctatacttag cacacttcca ctgtgtgtga ctgtctggtc tgactgagac aagttttcaa
    19021 ggattcgtaa cgtgattagc gatatcagaa aagatgctga agtacgcatg gacaaatgcg
    19081 tagaagcgtt caaaacccaa atcagcaaaa tacgcacggg tcgtgcttct cccagcctgc
    19141 tggatggcat tgtcgtggaa tattacggca cgccgacgcc gctgcgtcag ctggcaagcg
    19201 taacggtaga agattcccgt actctgaaaa tcaacgtgtt tgatcgttca atgtctccgg
    19261 ccgttgaaaa agcgattatg gcgtccgatc ttggcctgaa cccgaactct gcgggtagcg
    19321 acatccgtgt tccgctgccg ccgctgacgg aagaacgtcg taaagatctg accaaaatcg
    19381 ttcgtggtga agcagaacaa gcgcgtgttg cagtacgtaa cgtgcgtcgt gacgcgaacg
    19441 acaaagtgaa agcactgttg aaagataaag agatcagcga agacgacgat cgccgttctc
    19501 aggacgatgt acagaaactg actgatgctg caatcaagaa aattgaagcg gcgctggcag
    19561 acaaagaagc agaactgatg cagttctgat ttcttgaacg acaaaaacgc cgctcagtag
    19621 atccttgcgg atcggctggc ggcgttttgc tttttattct gtctcaactc tggatgtttc
    19681 atgaagcaac tcaccattct gggctcgacc ggctcgattg gttgcagcac gctggacgtg
    19741 gtgcgccata atcccgaaca cttccgcgta gttgcgctgg tggcaggcaa aaatgtcact
    19801 cgcatggtag aacagtgcct ggaattctct ccccgctatg ccgtaatgga cgatgaagcg
    19861 agtgcgaaac ttcttaaaac gatgttacag caacagggta gccgcaccga agtcttaagt
    19921 gggcaacaag ccgcttgcga tatggcagcg cttgaggatg ttgatcaggt gatggcagcc
    19981 attgttggcg ctgctgggct gttacctacg cttgctgcga tccgcgcggg taaaaccatt
    20041 ttgctggcca ataaagaatc actggttacc tgcggacgtc tgtttatgga cgccgtaaag
    20101 cagagcaaag cgcaattgtt accggtcgat agcgaacata acgccatttt tcagagttta
    20161 ccgcaaccta tccagcataa tctgggatac gctgaccttg agcaaaatgg cgtggtgtcc
    20221 attttactta ccgggtctgg tggccctttc cgtgagacgc cattgcgcga tttggcaaca
    20281 atgacgccgg atcaagcctg ccgtcatccg aactggtcga tggggcgtaa aatttctgtc
    20341 gattcggcta ccatgatgaa taaaggtctg gaatacattg aagcgcgttg gctgtttaac
    20401 gccagcgcca gccagatgga agtgctgatt cacccgcagt cagtgattca ctcaatggtg
    20461 cgctatcagg acggcagtgt tctggcgcag ctgggggaac cggatatgcg tacgccaatt
    20521 gcccacacca tggcatggcc gaatcgcgtg aactctggcg tgaagccgct cgatttttgc
    20581 aaactaagtg cgttgacatt tgccgcaccg gattatgatc gttatccatg cctgaaactg
    20641 gcgatggagg cgttcgaaca aggccaggca gcgacgacag cattgaatgc cgcaaacgaa
    20701 atcaccgttg ctgcttttct tgcgcaacaa atccgcttta cggatatcgc cgcgttgaat
    20761 ttatccgtac tggaaaaaat ggatatgcgc gaaccacaat gtgtggacga tgtgttatct
    20821 gttgatgcga acgcgcgtga agtcgccaga aaagaggtga tgcgtctcgc aagctgagga
    20881 taatccggct acagagagtc gcgctatttg ttagcgtagg gcttcagtga tatagtctgc
    20941 gccatctgat cgtaagtagt tggctttata aggtcaggta tgccgtggtt ttacacggct
    21001 tttttttgta taggcttcag tattcctgag taccgtaaac cctgtcaggg aataagaaac
    21061 gcgtgatgtt gtctgctact caaccactta gcgaaaaatt gccagcgcat ggctgtcgtc
    21121 atgttgcgat cattatggac ggcaatggtc gctgggcaaa aaagcaaggg aagattcgtg
    21181 cctttgggca taaagccggg gcaaaatccg tccgccgggc tgtctctttt gcggccaaca
    21241 acggtattga ggcgttaact ctgtatgcct ttagtagtga aaactggaac cgaccagcgc
    21301 aggaagtcag tgcgttaatg gaactgtttg tgtgggcgct tgatagcgaa gtaaagagtc
    21361 tgcaccgaca taacgtgcgt ctgcgtatta ttggcgatac cagtcgcttt aactcgcgtt
    21421 tgcaagaacg tattcgtaaa tctgaagcgc taacagccgg gaataccggt ctgacgctga
    21481 atattgcggc gaactacggt ggacgttggg atatagtcca gggagtcagg caactggctg
    21541 aaaaggtgca gcaaggaaac ctgcaaccag atcagataga tgaagagatg ctaaaccagc
    21601 atgtctgtat gcatgaactg gcccctgtag atttagtaat taggactggg ggagagcatc
    21661 gcattagtaa ctttttgctt tggcaaattg cctatgccga actttacttt acagatgttc
    21721 tctggcccga tttcgatgaa caagactttg aaggggcgtt aaatgccttt gctaatcgag
    21781 agcgtcgttt cggcggcacc gagcccggtg atgaaacagc ctgatggggg tcgcttttgc
    21841 tgaagtatcg cctgatatct gcttttgtgt taatacccgt cgtcatcgcg gcgttgtttc
    21901 tgttgccgcc ggtggggttc gccattgtaa cgctggtggt ctgcatgctg gcagcgtggg
    21961 aatggggaca gcttagcggt tttaccactc gtgcgcagcg agtatggttg gcggtgttat
    22021 gtgggttatt gttggcgctg atgctttttc tgttgccgga atatcaccga aatattcatc
    22081 aaccgctggt tgaaatctca ctttgggctt cgctgggttg gtggattgtc gcgctattgc
    22141 tggtgctgtt ttacccaggt tccgcagcaa tctggcgtaa ctctaaaaca ttgcgcatta
    22201 tttttggcgt gctaaccatt gttcccttct tctggggcat gctggcgtta cgggcctggc
    22261 actacgacga gaatcattac agtggcgcaa tatggctgct ctatgtcatg atcctggtat
    22321 ggggcgctga ctctggcgca tatatgtttg gcaaattgtt tggtaaacat aagctggctc
    22381 cgaaggtttc tccgggtaaa acctggcaag gctttatcgg tggactcgcg actgcagcgg
    22441 taatctcatg gggttatggc atgtgggcga atctcgacgt cgctcccgtc accttactca
    22501 tttgctctat tgtcgcagcg ttagcctcag tgctcggcga tctgaccgaa agtatgttta
    22561 agcgtgaagc aggaattaag gacagcggtc atttaattcc aggacacggt ggtattttag
    22621 atcgtattga tagcctgacg gctgcggtac cggtctttgc ttgcttgttg ttactggtat
    22681 tcaggacgct ttaacggaag gtaatatgct gagttttctc tgggatttgg cttcgttcat
    22741 cgttgcactg ggtgtactta tcaccgtgca tgaatttggt catttctggg ttgcccggcg
    22801 ttgtggtgtt cgcgttgagc gtttctcaat agggtttggt aaggcgctct ggcggcgaac
    22861 tgataagctc ggcaccgaat atgttatcgc cctgatcccg ttgggcggtt atgtcaaaat
    22921 gctggatgag cgcgcagaac cggtcgttcc ggaactccgc caccatgcct tcaataataa
    22981 atctgtcggc caacgagcgg cgattattgc cgcaggtccg gttgcaaact tcatttttgc
    23041 tatctttgcc tactggctgg tttttattat tggtgtgcct ggtgtacgtc cggtggttgg
    23101 cgaaatagca gccaattcga tagctgcgga agcacaaatt gcaccaggta cggaactaaa
    23161 agccgtagat ggtatcgaaa cgcctgattg ggatgccgtg cgtttgcagt tggtcgataa
    23221 aattggcgat gaaagcacca ccattacggt agcgccattt ggcagcgacc aacggcggga
    23281 tgtaaagctc gatttacgtc actgggcgtt tgagcctgat aaagaagatc cggtaacttc
    23341 gctggggatt cgtcctcgtg ggccgcaaat tgaacctgta ctggaaaatg tgcagccaaa
    23401 ctcggcggca agcaaggcag gtttgcaagc aggcgacagg atcgttaaag tcgatggtca
    23461 gcccttaacg cagtgggtga cctttgtgat gcttgtccgg gataacccgg gtaaatcctt
    23521 agcgttagaa atcgaaaggc aggggaatcc cttgtctttg acattaatcc cggagagtaa
    23581 accgggtaat ggtaaagcga ttggttttgt cggtattgag ccgaaagtca ttcctttgcc
    23641 agatgagtat aaagttgtac gccagtatgg accgttcaac gccattgtcg aagccacgga
    23701 caaaacgtgg cagttgatga agctgacggt cagtatgctg ggaaaattga tcaccggtga
    23761 tgtgaaactg aacaacctca gtgggccgat ctctatcgcc aagggggctg ggatgacagc
    23821 ggaactcggg gttgtttatt acctgccgtt tcttgcgctt attagcgtga acttagggat
    23881 aattaacctg tttccgttgc ccgtacttga cggggggcat ctgctgttcc ttgcgatcga
    23941 aaagatcaag ggcggaccgg tatccgagcg ggttcaagac ttttgttatc gcattggctc
    24001 gattctgctg gtgctgttaa tggggcttgc acttttcaat gatttctctc ggttatgaga
    24061 gttagttagg aagaacgcat aataacgatg gcgatgaaaa agttgctcat agcgtcgctg
    24121 ctgtttagca gcgccaccgt atacggtgct gaagggttcg tagtgaaaga tattcatttc
    24181 gaaggccttc agcgtgtcgc cgttggtgcg gccctcctca gtatgccggt gcgcacaggc
    24241 gacacggtta atgatgaaga tatcagtaat accattcgcg ctctgtttgc taccggcaac
    24301 tttgaggatg ttcgcgtcct tcgtgatggt gatacccttc tggttcaggt aaaagaacgt
    24361 ccgaccattg ccagcattac tttctccggt aacaaatcgg tgaaagatga catgctgaag
    24421 caaaacctcg aggcttctgg tgtgcgtgtg ggcgaatccc tcgatcgcac caccattgcc
    24481 gatatcgaga aaggtctgga agacttctac tacagcgtcg gtaaatatag cgccagcgtt
    24541 aaagctgtcg tgaccccgct gccgcgcaac cgtgttgacc taaaactggt gttccaggaa
    24601 ggtgtgtcag ctgaaatcca gcaaattaac attgttggta accatgcttt caccaccgac
    24661 gaactgatct ctcatttcca actgcgtgac gaagtgccgt ggtggaacgt ggtcggcgat
    24721 cgtaaatacc agaaacagaa actggcgggc gaccttgaaa ccctgcgcag ttactatctg
    24781 gatcgcggtt atgcccgttt caacatcgac tctacccagg tcagtctgac gccagataaa
    24841 aaaggtattt acgtcacggt gaacatcacc gaaggcgatc agtacaagct ttctggcgtt
    24901 gaagtgagcg gcaatcttgc cgggcactcc gctgaaattg agcagctgac taagatcgag
    24961 ccgggcgagc tgtataacgg caccaaagtg accaagatgg aagatgacat taaaaagctt
    25021 ctcggtcgct atggttatgc ctatccgcgc gtacagtcga tgcctgaaat taacgatgcc
    25081 gacaaaaccg ttaaattacg cgtgaacgtt gatgctggta accgtttcta tgtgcgtaag
    25141 atccgttttg aaggtaacga tacctcgaaa gatgccgtcc tgcgtcgcga aatgcgtcag
    25201 atggaaggtg catggctggg gagcgatctg gtcgatcagg gtaaggagcg tctgaatcgt
    25261 ctgggcttct ttgaaactgt cgataccgat acccaacgtg ttccgggtag cccggaccag
    25321 gttgatgtag tctacaaggt gaaagaacgt aacactggta gcttcaactt cgggattggt
    25381 tacggtactg aaagtggcgt gagcttccag gctggcgtgc aacaggataa ctggttaggt
    25441 acaggttatg ctgttggtat caacgggacc aaaaacgatt accagaccta tgctgaactg
    25501 tcggtaacca acccgtactt caccgtagat ggcgtaagcc tcggtggtcg tctcttctat
    25561 aatgacttcc aggcagatga cgccgacctg tccgactata ccaacaagag ttatggtaca
    25621 gacgtgacgt tgggcttccc gatcaacgaa tataactcgc tgcgtgcagg tctgggttat
    25681 gttcataact ccctgtccaa catgcagccg caggttgcga tgtggcgtta tctgtactct
    25741 atgggtgaac atccgagcac ctctgatcag gataacagct tcaaaacgga cgacttcacg
    25801 ttcaactatg gttggaccta taacaagctt gaccgtggtt acttcccgac agatggttca
    25861 cgtgtcaacc tgaccggtaa agtgaccatt ccgggatcgg ataacgaata ctacaaagtg
    25921 acgttagaca cggcgactta tgtgccgatt gatgacgatc acaaatgggt tgttctgggt
    25981 cgtacccgct ggggttatgg tgatggttta ggcggcaaag agatgccgtt ctatgagaac
    26041 ttctatgccg gtggttccag caccgtgcgt ggcttccagt ccaataccat tggtccgaaa
    26101 gcagtttact tcccgcatca ggccagtaat tatgatccgg actatgatta cgaatgtgcg
    26161 actcaggacg gcgcgaaaga cctgtgtaaa tcggatgatg ctgtaggcgg taacgctatg
    26221 gcggttgcca gcctcgagtt catcaccccg acgccgttca ttagcgacaa gtatgctaac
    26281 tcggttcgta cttccttctt ctgggatatg ggtaccgttt gggatacaaa ctgggattcc
    26341 agccaatatt ctggatatcc ggactatagt gatccaagca atatccgtat gtctgcgggt
    26401 atcgcattac aatggatgtc cccattgggg ccgttggtgt tctcctacgc ccagccgttc
    26461 aaaaagtacg atggagacaa ggcagaacag ttccagttta acatcggtaa aacctggtaa
    26521 gtgttctcca caaaggaatg tagtggtagt gtagcgatga ctttaggcga tcaatataag
    26581 atcgccgggc cacgcaaaga actgcacctt ccggtgcaaa tgggatggta aggagtttat
    26641 tgtgaaaaag tggttattag cggcaggtct cggtttagca ctggcaactt ctgctcaggc
    26701 ggctgacaaa attgcaatcg tcaatatggg cagcctgttc cagcaggtag cgcagaaaac
    26761 cggtgtttct aacacgctgg aaaatgagtt caaaggccgt gccagcgaac tgcagcgtat
    26821 ggaaaccgat ctgcaggcta aaatgaaaaa gctgcagtcc atgaaagcgg gcagcgatcg
    26881 cactaagctg gaaaaagacg tgatggctca gcgccagact tttgctcaga aagcgcaggc
    26941 ttttgagcag gatcgcgctc gtcgttccaa cgaagaacgt ggcaaactgg ttactcgtat
    27001 ccagactgct gtgaaatccg ttgccaacag ccaggatatc gatctggttg ttgatgcaaa
    27061 cgccgttgct tacaacagca gcgatgtaaa agacatcact gctgacgtac tgaaacaggt
    27121 taaataagta atgccttcaa ttcgactggc tgatttagcg cagcagttgg atgcagaact
    27181 acacggtgat ggcgatatcg tcatcaccgg cgttgcgtcc atgcaatctg cacaaacagg
    27241 tcacattacg ttcatggtta acccaaaata ccgtgagcat ttaggcttgt gccaggcgtc
    27301 cgcggttgtc atgacccagg acgatcttcc tttcgcgaaa agtgccgcgc tggtagtgaa
    27361 gaatccctac ctgacttacg cgcgcatggc gcaaatttta gataccacgc cgcagcccgc
    27421 gcagaacatt gcacccagtg cagtgattga cgcgacggcg aagctgggta acaacgtctc
    27481 aattggcgct aacgcggtga ttgagtccgg cgttgaactg ggcgataacg tgattatcgg
    27541 tgccggttgc ttcgtaggta aaaacagcaa aatcggtgca ggttcgcgtc tctgggcgaa
    27601 cgtaaccatt taccatgaga tccagatcgg tcagaattgc ctgatccagt ccggaacagt
    27661 ggtaggcgca gacggctttg gttatgccaa cgatcgtggt aactgggtga agatcccgca
    27721 gataggtcgc gtaattattg gcgatcgcgt ggagatcggc gcatgtacta ccatcgatcg
    27781 cggtgcgctg gatgacactg ttattggcaa tggtgtgatc attgataacc agtgccagat
    27841 tgcacataac gtcgtgattg gcgacaatac ggcagttgcc ggtggcgtca ttatggcggg
    27901 cagcctgaaa attggtcgtt actgcatgat cggcggagcc agcgtaatca acgggcatat
    27961 ggaaatatgc gacaaagtga cggttacggg catgggtatg gtgatgcgtc ccatcactga
    28021 accaggcgtc tattcctcag gcattccgct gcaacccaac aaagtctggc gcaaaaccgc
    28081 tgcactggtg atgaacattg atgacatgag caagcgtctg aaatcgcttg agcgcaaggt
    28141 taatcaacaa gactaacgtt ccatcttttg ttcgccaaac tttacggcct gtctcattct
    28201 tacgattgcg gcaggccgtg ttattattgt cgtttcttat attttgacag gaagagtatc
    28261 ttgactacta acactcatac tctgcagatt gaagagattt tagaacttct gccgcaccgt
    28321 ttcccgttct tactggtgga tcgcgtgctg gattttgaag aaggtcgttt tctgcgcgca
    28381 gtaaaaaatg tctctgtcaa tgagccattc ttccagggcc atttccctgg aaaaccgatt
    28441 ttcccgggtg tgctgattct ggaagcaatg gcacaggcaa caggtattct ggcgtttaaa
    28501 agcgtaggaa aactggaacc gggtgagctg tactacttcg ccggtattga cgaagcgcgc
    28561 tttaagcgcc cggtcgtgcc tggcgatcaa atgatcatgg aagtcacttt cgaaaaaacg
    28621 cgccgcggcc tgacccgttt taaaggggtt gctctggtcg acggtaaagt agtttgcgaa
    28681 gcaacgatga tgtgtgctcg tagccgggag gcctgatacg tgattgataa atccgccttt
    28741 gtgcatccaa ccgccattgt ggaagagggc gcgtcgattg gcgcgaacgc tcacattggt
    28801 cctttttgta tcgttggacc ccatgtcgaa attggtgagg gtaccgtact gaaatctcac
    28861 gttgtcgtga atggtcatac taaaattggc cgcgataatg agatttatca gttcgcctcc
    28921 atcggcgaag ttaaccagga tctgaaatat gctggcgaac cgacccgcgt ggaaatcggc
    28981 gatcgtaacc gcattcgcga aagcgtcacc attcatcgtg gcacagtcca gggcggtgga
    29041 ttgacgaagg tgggcagcga caacttactg atgatcaatg cgcacattgc gcacgattgt
    29101 acggtaggta accgctgcat cctcgccaac aacgcaacgc tggcgggtca cgtatcggtt
    29161 gacgacttcg cgatcatcgg cggcatgacc gcagtccatc agttctgcat cattggtgcg
    29221 catgtgatgg ttggcggctg ctccggtgtg gcgcaggacg tccctcctta tgtcattgcg
    29281 cagggtaacc acgcaacgcc gttcggtgtc aatatcgaag ggctgaagcg ccgcggattc
    29341 agccgtgagg cgattaccgc tatccgcaat gcgtataagc tgatttatcg tagcggtaaa
    29401 acgctcgatg aagtgaaacc ggaaattgct gaactggcgg aaacatatcc ggaagtgaaa
    29461 gcctttaccg atttctttgc acgctcaacg cgcggtctga ttcgttaatg actgaacagc
    29521 gtccattaac gattgccctg gtcgccggag aaacctccgg cgatatcctg ggggccggtt
    29581 taatccgtgc tctgaaagaa cgtgtgccca atgcccgctt tgttggtgtt gccgggccac
    29641 gaatgcaagc cgaaggctgc gaagcctggt acgaaatgga agagctggcg gtgatgggca
    29701 ttgttgaagt gctcgggcgt ctgcgccgct tactgcatat tcgtgccgat ctgacaaagc
    29761 gttttggcga actgaagcca gatgtttttg tcggtattga tgcgcctgac ttcaatatta
    29821 cccttgaagg taaccttaaa aagcagggga tcaaaaccat tcattatgtc agcccgtccg
    29881 tctgggcgtg gcgacagaaa cgcgttttca aaataggcag agccaccgat ctggtgctcg
    29941 catttctgcc tttcgaaaaa gcgttttatg acaaatacaa cgtaccgtgc cgctttatcg
    30001 gtcataccat ggctgatgcc atgccattag atccagataa aaatggtgcc cgtgatgtgc
    30061 tggggatctc tcacgatgcc cactgtctgg cattgttgcc gggcagccgt ggtgcagaag
    30121 tcgaaatgct tagcgccgat tttctgaaaa cggcccagct tttgcgccag acatatccgg
    30181 atctcgaaat cgtggtgccg ctggtgaatg ccaaacgccg cgagcagttt gaacgcatca
    30241 aagctgaagt tgcgccagac ctgtcggttc atatgctgga tgggttgggc cgtgaggcga
    30301 tggtcgccag tgatgcggcg ctactggcgt cgggtacggc agcactggag tgtatgctgg
    30361 ctaaatgccc gatggtagtg ggatatcgca tgaagccttt taccttctgg ctggcgaagc
    30421 gactggtgaa aactgattat gtctctctac ccaatttgct ggcgggcaga gagttagtca
    30481 aagagttatt gcaggaagag tgtgagccgc aaaaactggc tgcggcgctg ttaccgctgt
    30541 tggcgaacgg gaaaaccagc cacgcgatgc acgatacctt ccgtgaactg catcagcaga
    30601 tccgctgcaa tgccgatgag caggcggcac aagccgttct ggagttagca caatgatcga
    30661 atttgtttat ccgcacacgc agctggttgc gggtgtggat gaagtcggac gcgggccgtt
    30721 agttggcgcg gtcgtcaccg ctgcagtgat ccttgacccg tcgcgcccga ttgccgggct
    30781 gaatgattcc aaaaagctga gcgaaaaacg ccgtctggcg ctctgcgaag agatcaaaga
    30841 gaaagcgttg agctggagtc tgggccgcgc ggaaccccac gaaatcgacg aactgaatat
    30901 tttacacgcg accatgctgg cgatgcagcg tgccgtcgct gggctgcata ttgcgccgga
    30961 atatgtgttg attgatggta accgctgccc gaaattaccg atgcctgcga tggctgtggt
    31021 gaaaggcgat agccgcgtac cggaaatcag tgccgcgtct atcctggcga aagtgacgcg
    31081 tgacgccgaa atggcggcgc tggatattgt tttcccgcaa tatggttttg cccaacacaa
    31141 agggtatcca accgcttttc atctggaaaa actggctgaa tatggcgcga ctgaacatca
    31201 tcgtcgcagc tttgggcctg tcaaacgcgc actgggactt gcgtcctgat tcttgtgtcg
    31261 agattaagta aaccggaatc tgaagatgtc tgaaccacgt ttcgtacacc tgcgggtgca
    31321 cagcgactac tcgatgatcg atggcctggc caaaaccgca ccgctggtaa aaaaggcggc
    31381 ggcgttgggt atgccagcac tggcgatcac cgatttcacc aacctttgtg gtctggtgaa
    31441 gttctacgga gcgggacatg gcgcagggat taagcctatc gtcggggcag attttaatgt
    31501 ccagtgtgac ctgctgggtg atgagttaac ccacctgacg gtgctggcgg cgaacaatac
    31561 cggctatcag aatctgacgt tgctgatctc aaaagcgtat cagcgcgggt acggtgccgc
    31621 cgggccgatc atcgatcgcg actggcttat cgaattaaac gaagggttga tccttctttc
    31681 cggcgggcgc atgggcgacg ttggacgcag tcttttgcgt ggtaacagcg cgctggtaga
    31741 tgagtgtgtc gcgttttatg aagaacactt cccggatcgc tattttctcg agctgatccg
    31801 caccggcagg ccggacgaag aaagctatct gcacgcggcg gtggaactgg cggaagcgcg
    31861 cggtttaccc gtcgtggcga ccaacgacgt gcgctttatc gacagcagcg actttgacgc
    31921 acacgaaatc cgcgtcgcga tccacgacgg ctttaccctc gacgatccta aacgcccgcg
    31981 taactattcg ccgcagcaat atatgcgtag cgaagaggag atgtgtgagc tgtttgccga
    32041 catccccgaa gcccttgcca acaccgttga gatcgccaaa cgctgtaacg tgaccgtgcg
    32101 ccttggtgaa tacttcctgc cgcagttccc gaccggggac atgagcaccg aagattatct
    32161 ggtcaagcgt gcaaaagaag gcctggaaga gcgtctggcc tttttattcc ctgacgagga
    32221 agaacgtctg aagcgccgcc cggaatatga cgagcgtctg gagactgaac ttcaggttat
    32281 caaccagatg ggcttcccgg gttacttcct catcgttatg gaatttatcc agtggtcgaa
    32341 agataacggc gtaccggtag ggccaggccg tggctccggt gcgggttcac tggtggccta
    32401 cgcgctgaaa atcaccgacc tcgatccgct ggaatttgac ctgctgttcg aacgtttcct
    32461 taacccggaa cgtgtctcca tgcctgactt cgacgttgac ttctgtatgg agaaacgcga
    32521 ccaggttatc gaacacgtcg cggacatgta cggtcgtgat gcggtatcgc agattatcac
    32581 cttcggtacg atggcggcga aagcggtgat ccgcgacgta ggccgcgtac tggggcatcc
    32641 gtacggcttt gtcgaccgta tctcgaaact gatcccgccc gatccgggga tgacgctggc
    32701 gaaagcgttt gaagccgagc cgcagctgcc ggaaatctac gaagcggatg aagaagttaa
    32761 ggcgctgatc gacatggcgc gcaaactgga aggggtcacc cgtaacgccg gtaagcacgc
    32821 cggtggggtg gttatcgcac cgaccaaaat taccgatttt gcgccgcttt actgcgatga
    32881 agagggcaaa catccagtca cccagtttga taaaagcgac gttgaatacg ccggactggt
    32941 gaagttcgac ttccttggtt tgcgtacgct caccatcatc aactgggcgc tggagatgat
    33001 caacaagcgg cgggcgaaga atggcgagcc gccgctggat attgccgcga tcccgctgga
    33061 tgacaagaaa agcttcgaca tgctgcaacg ctcggaaacc acggcggtat tccagcttga
    33121 atcgcgcggc atgaaggacc tgatcaagcg tctgcaacct gactgcttcg aagatatgat
    33181 cgcactggtg gcactgttcc gccccggtcc gttgcaatca gggatggtgg ataactttat
    33241 cgaccgtaaa catggtcgcg aagagatctc ctatccggac gtgcagtggc agcatgaaag
    33301 cctgaaaccg gtactggagc caacctacgg catcatcctg tatcaggaac aggtcatgca
    33361 gattgcccag gtgctttctg gttataccct cggtggcgcg gatatgctgc gtcgtgcgat
    33421 gggtaagaaa aagccggaag agatggctaa gcagcgttct gtatttgctg aaggtgcaga
    33481 aaagaacgga atcaacgccg aactggcgat gaaaatcttc gacctggtgg agaaattcgc
    33541 gggttacgga tttaacaaat cgcactctgc ggcctatgct ttggtgtcat atcaaacgtt
    33601 atggctgaaa gcgcactatc cggcggagtt tatggcggcg gtaatgaccg ccgatatgga
    33661 caacaccgag aaggtggtgg gcctggtgga tgagtgctgg cggatggggc tgaaaatcct
    33721 accgccggat ataaactccg gtctttacca tttccacgtc aacgacgacg gcgaaatcgt
    33781 gtatggtatt ggcgcgatca aaggggtagg tgaaggcccg attgaggcca tcatcgaagc
    33841 ccgcaataaa ggcggctact tccgcgaact gtttgatctc tgcgcccgta ccgacaccaa
    33901 aaagttaaac cggcgagtgc tggaaaaact gatcatgtcc ggggcgtttg accgtcttgg
    33961 gccacaccgc gcggcgctga tgaactcgct gggcgatgcg ttaaaagcgg cagatcaaca
    34021 cgcgaaagcg gaagctatcg gtcaggccga tatgttcggc gtgctggccg aagagccgga
    34081 acaaattgaa caatcctacg ccagctgcca accgtggccg gagcaggtgg tgttagatgg
    34141 ggaacgcgaa acgttaggtc tgtacctcac gggacaccct atcaaccagt atttaaaaga
    34201 gattgagcgt tatgtcggag gcgtaaggct gaaagacatg cacccgacag aacgtggtaa
    34261 agtcatcacg gctgcggggc tcgttgttgc cgcgcgggtt atggtcacca agcgcggcaa
    34321 tcgtatcggt atctgcacgc tggatgaccg ttccgggcgg ctggaagtga tgttgtttac
    34381 tgacgccctg gataaatacc agcaattgct ggaaaaagac cgcatactta tcgtcagcgg
    34441 acaggtcagc tttgatgact tcagcggtgg gcttaaaatg accgctcgcg aagtgatgga
    34501 tattgacgaa gcccgggaaa aatatgctcg cgggcttgct atctcgctga cggacaggca
    34561 aattgatgac cagcttttaa accgactccg tcagtctctg gaaccccacc gctctgggac
    34621 aattccagta catctctact atcagagggc ggatgcacgc gcgcggttgc gttttggcgc
    34681 gacgtggcgt gtctctccga gcgatcgttt attaaacgat ctccgtggcc tcattggttc
    34741 ggagcaggtg gaactggagt ttgactaata caggaatact atgagtctga atttccttga
    34801 ttttgaacag ccgattgcag agctggaagc gaaaatcgat tctctgactg cggttagccg
    34861 tcaggatgag aaactggata ttaatatcga tgaagaagtg catcgtctgc gtgaaaaaag
    34921 cgtagaactg acgcgtaaaa tcttcgccga tctcggtgca tggcagattg cgcaactggc
    34981 acgccatcca cagcgtcctt ataccctgga ttacgttcgc ctggcatttg atgaatttga
    35041 cgaactggct ggcgaccgcg cgtatgcaga cgataaagct atcgtcggtg gtatcgcccg
    35101 tctcgatggt cgtccggtga tgatcattgg tcatcaaaaa ggtcgtgaaa ccaaagaaaa
    35161 aattcgccgt aactttggta tgccagcgcc agaaggttac cgcaaagcac tgcgtctgat
    35221 gcaaatggct gaacgcttta agatgccaat catcaccttt atcgacaccc cgggggctta
    35281 tccgggcgtg ggcgcagaag aacgcggtca gtctgaagcc attgcacgca acctgcgtga
    35341 aatgtctcgc cttagcgtac cgactatttg taccgttatc ggtgaaggtg gttctggcgg
    35401 cgcgctggcg attggcgtgg gcgataaagt gaatatgctg caatacagca cctattccgt
    35461 tatctcgccg gaaggttgtg cgtccattct gtggaagagc gccgacaaag cgccgctggc
    35521 ggctgaagcg atgggtatca tcgctccgcg tctgaaagag ctgaaactga tcgactccat
    35581 catcccggaa ccgctgggcg gcgctcaccg taacccggaa gcgatggcgg catcgttgaa
    35641 agcgcaactg ctggcggatc tggccgatct cgacgtgtta agcactgaag atttaaaaaa
    35701 tcgtcgttat cagcgcctga tgagctacgg ttacgcgtaa ttcgcaaaag ttctgaaaaa
    35761 gggtcacttc ggtggccctt ttttatcgcc acggtttgag caggctatga ttaaggaagg
    35821 attttccagg aggaacacat gaacatcatt gccattatgg gaccgcatgg cgtcttttat
    35881 aaagatgagc ccatcaaaga actggagtcg gcgctggtgg cgcaaggctt tcagattatc
    35941 tggccacaaa acagcgttga tttgctgaaa tttatcgaac ataaccctcg aatttgcggc
    36001 gtgatttttg actgggatga gtacagtctc gatttatgta gcgatatcaa tcagcttaat
    36061 gaatatctcc cgctttatgc cttcatcaac acccactcga cgatggatgt cagcgtgcag
    36121 gatatgcgga tggcgctctg gttttttgaa tatgcgctgg ggcaggcgga agatatcgcc
    36181 attcgtatgc gtcagtacac cgacgaatat cttgataaca ttacaccgcc gttcacgaaa
    36241 gccttgttta cctacgtcaa agagcggaag tacacctttt gtacgccggg tcatatgggc
    36301 ggcaccgcat atcaaaaaag cccggttggc tgtctgtttt atgatttttt cggcgggaat
    36361 actcttaagg ctgatgtctc tatttcggtt accgagcttg gttcgttgct cgaccacacc
    36421 gggccacacc tggaagcaga agagtacatc gcgcggactt ttgacgcgga acagagttat
    36481 atcgttacca acggaacatc gacgtcgaac aaaattgtgg gtatgtacgc cgcgccgtcc
    36541 ggcagtacgc tgttaattga ccgcaattgt cataaatcgc tggcgcatct gttgatgatg
    36601 aacgatgtag tgccagtctg gctgaaaccg acgcgtaatg cgttggggat tcttggtggg
    36661 atcccgcgcc gtgaattttc tcgcgacagt atcgaagaga aagtcgctgc caccacgcaa
    36721 gcacaatggc cggttcatgc ggtgatcacc aactcaacct atgatggctt gctctacaac
    36781 accgactgga tcaaacagac gctggatgtc ccctcgatcc acttcgattc cgcctgggtg
    36841 ccgtacaccc attttcatcc gatctaccag ggtaaaagtg gtatgagcgg cgagcgtgtt
    36901 gcgggaaaag tgatcttcga aacgcaatcg acccacaaaa tgctggcggc gttatcccag
    36961 gcttcgctga tccacattaa aggtgagtat gacgaagagg cgtttaacga agcctttatg
    37021 atgcatacca ccacctcacc cagttatccc attgttgctt cggttgagac ggcggcggcg
    37081 atgctgcgtg gtaatccggg caaacggctg attaaccgtt cggtggagcg ggcgctgcat
    37141 tttcgcaaag aggtccagcg gctgcgggaa gagtctgacg gctggttttt cgatatctgg
    37201 caaccgccgc aggtggatga agccgaatgc tggcccgttg cgcctggcga acagtggcac
    37261 ggctttaacg atgcggatgc cgatcatatg tttctcgatc cggttaaagt cactattttg
    37321 acaccgggga tggacgagca gggcaatatg agcgaggagg ggatcccggc ggcgctggta
    37381 gcaaaattcc tcgacgaacg agggatcgta gtagagaaaa ccggtcctta taacctgctg
    37441 tttctcttta gtattggaat cgataaaacc aaagcaatgg gattattgcg tgggttgacg
    37501 gaatttaagc gctcttacga tctcaacctg cggatcaaaa atatgctgcc cgatctctat
    37561 gctgaagatc ccgatttcta ccgcaatatg cgcattcagg atctggcgca agggatccat
    37621 aagctgattc gtaaacacga tcttcccggt ttgatgttgc gggcatttga taccttgccg
    37681 gagatgatca tgacgccaca tcaggcatgg cagagacaga ttaaaggtga agtagaaacc
    37741 attgcgctgg aacaactggt cggtagagta tcggcaaata tgatcctgcc ttatccaccg
    37801 ggcgtaccgc tgttgatgcc tggagaaatg ctgaccaaag agagccgcac agtactcgat
    37861 tttctactga tgctttgttc cgtagggcaa cattaccccg gttttgaaac ggatattcac
    37921 ggcgcgaaac aggacgaaga tggcgtttac cgcgtacgag tcctaaaaat ggcgggataa
    37981 cttgccagag cggcttccgg gcgagtaacg tgctgttaac aaataaagga gacgttatgc
    38041 tgggtttaaa acaggttcac catattgcga ttattgcgac ggattatgcg gtgagcaaag
    38101 ctttctactg cgatattctt ggtttcacgc tgcaaagcga agtctatcgc gaagcgcgcg
    38161 actcgtggaa aggggatttg gcgcttaatg ggcaatatgt gattgagctt ttctcatttc
    38221 cgttcccgcc ggagcgcccc agccgaccgg aagcttgcgg cctgcgtcat ctggctttta
    38281 gcgttgatga tatcgatgcg gcagtggcgc accttgaaag ccataacgtg aagtgtgaag
    38341 ccatccgtgt cgatccatac acgcaaaaac gcttcacgtt ctttaacgat cccgacgggc
    38401 tgccgttgga actgtatgag cagtaaggct tgtcatcgcc gcatttgccc ggtaacgtgc
    38461 cgggcattgc tactgtaaaa tcgcaccatc atgacactca cgctcaatag acaacttctc
    38521 tcctcacgcc agattctggt ggcctttagc ggcgggcttg actccaccgt tctgctgcat
    38581 cagttggtgc agtggcggac ggaaaatccg ggcgtcactc tacgcgctat ccatgtgcat
    38641 cacggtttaa gtgccaatgc cgatgcctgg gttaggcatt gcgagaacat ctgccaacag
    38701 tggcaggtgc cgctggtggt cgagcgcgtg caacttgcgc aagaaggact gggcattgag
    38761 gcccaggcgc ggcaggtgcg ttatcaggca tttgctcgta ccctgttacc cggtgaagtg
    38821 ctggtcaccg cgcaacatct cgacgatcaa tgtgaaacct ttctgctggc gctaaaacgc
    38881 ggtagcggcc ctgccgggct ttcggctatg gcggaagtct cggagtttgc cggaacgcgg
    38941 cttatccgcc cgttgctcgc ccgcacgcgg ggagaactgg tgcagtgggc gcgtcagtat
    39001 gatttacgct ggattgaaga cgaaagtaat caggatgata gctacgatcg taacttcctg
    39061 cgcctgcgcg tggtgccgtt attgcagcag cgttggccgc attttgccga agcaacggcc
    39121 cgcagcgctg cgctttgcgc tgaacaagag agcctgttag atgaactgct ggcggatgat
    39181 atagcgcact gtcaaaagcc gcaggggacg ctgcagattg cgccaatgct ggcgatgagt
    39241 gatgcccgcc gcgcggcgat tatccgccgc tggctggcag ggcagaatgc accgatgcct
    39301 tcccgcgacg cgttggtgag gatctggcag gaagtggcgc tggcgcggga agatgcttcc
    39361 ccctgtttac gtctgggcgc gtttgaaatc cgccgctatc agtcgcaact gtggtggatt
    39421 aaatccgttg ccgggcaaag cgaaaccatt gtgccgtggc agacgtggct acaaccgctg
    39481 gaattaccgg cgggactggg aagtgtacag cttactgcgg gaggcgatat tcgccctccg
    39541 cgtgcagacg aagcggtcag cgtgcgtttc aaagcgccag gattgctgca tattatcggg
    39601 cgcaacggcg gacgtaagct gaagaaaatc tggcaagagc tgggtgtgcc gccgtggcta
    39661 cgtgacacca cgccactgct gttttatggc gaaacgttga ttgcggcggc aggggtattt
    39721 gtgacgcaag aaggtgtggc tgaaggtgag aatggcgtca gtcttgtctg gcagaaaacg
    39781 cttagttaag tgaaagccgg ataagacgct tcaaacgtcg catccggcga aagtcaatca
    39841 ggactcgctc accaccaccg taccaatttc cgggtggcta aagctggtaa ttttatccag
    39901 acgtagctcg cgggtttcgc cagcagcttc gacgaccaga tattccacat ttttgcggga
    39961 gactaaatcg ctggccttcc cctgcagttt ttcgccatct ttcagctcaa gtgtcagcat
    40021 taaatgatgc tggcaggcga gctcaagatt atcgtaatca tcacaattga ttggttgata
    40081 cgtatcattc attgacataa tcgctcacca gtaagtttgc cgcagcgtat gctgcttttt
    40141 ccctgacagc ctcagaaagg gcatcgtcgg cagccatttc attcagcact ttcaaaacgc
    40201 agcccagcgc gtccggaacg tatcctaagt ctccgctggc gatttccgcg taccgcttgc
    40261 gtattaactc acaatatttt tccacatgcc ctcctgtcag cactctgact taaccgtgga
    40321 tgcaagtcta agcctacgaa gataaactct gtttcgcaag gtgactatac cacactcatt
    40381 tctgcaatat cagcgccgca actgcacgta ttccgttaca atggcctcct gattcgaaag
    40441 gagttttctt atggcgctta aagcgacgat ttataaagcg acggttaatg tggccgatct
    40501 cgaccgcaac cagtttctcg atgcctctct gacgctggcg cgccatcctt cagaaaccca
    40561 ggagcgcatg atgctgcgcc tgctggcgtg gctgaaatat gctgatgaac gtctgcaatt
    40621 tacccgaggt ttgtgtgccg atgatgagcc ggaagcgtgg ctgcgtaacg atcacctggg
    40681 cattgattta tggattgaac tggggctgcc ggatgagcga cggattaaga aagcctgcac
    40741 tcaggccgca gaagtggcgc tgtttgccta taatagtcgg gcggcgcaaa tctggtggca
    40801 gcaaaatcag agcaaatgtg cgcagtttgc caatctttcc gtctggtatc tggacgatga
    40861 acaactggcg aaagtgagcg cctttgccga tcgtaccatg acgctgcagg caacgattca
    40921 ggatggtgtt atctggttat cggatgataa gaataatctg gaagtgaact taaccgtctg
    40981 gcaacaacct tcatgattgt gatttcccga catgttgcta tccctgatgg cgagtttgag
    41041 atcaccgcca ttcgtgcgca gggcgcgggc gggcagcatg ttaataagac ctcaacggct
    41101 attcatctgc gttttgacat tcgggcgtcc agcctgccag agtattacaa agagcgtctg
    41161 ctcgccgcca gccatcattt gatcagcagt gacggagtga ttgtcattaa ggcacaggaa
    41221 taccgcagtc aggaactgaa ccgcgaagcg gcgctggccc ggctggtggc agtgattaaa
    41281 gatttaacaa cagaacaaaa agcccgacga cctacgcggc ccacccgtgc atcgaaagag
    41341 cgcaggctgg catcgaaagc acaaaaatca agcgtgaagg cgatgcgcgg caaagtgcgc
    41401 agcggtcggg aataaaaaga aggaatggat ggtgaaaaaa gcgatagtga cagcgatggc
    41461 tgtaatcagc ctctttactc tgatgggatg taataatcgg gccgaagtcg atacgctttc
    41521 tccggcacag gctgccgaac tgaaaccgat gccgcaaagt tggcgcggcg tgctgccgtg
    41581 tgctgattgc gaaggaatcg aaacctctct gttcctcgaa aaagacggaa cctgggtgat
    41641 gaatgagcgt tatctggggg ctcgtgaaga accttcctcc ttcgcttcct acggtacatg
    41701 ggcgcgaacc gctgacaagc tggtattaac cgatagcaaa ggtgaaaagt catattatcg
    41761 cgcgaaagga gatgcgctgg agatgctcga tcgtgaaggt aatccgattg aatcgcagtt
    41821 caactatacg ctggaaccgg cacaatccag cttacccatg acaccgatga ccctgcgggg
    41881 catgtatttt tatatggctg atgcggcgac cttcactgat tgcgcgaccg gaaaacgttt
    41941 catggtggcg aataacgcag agctggagcg tggctacctg gctgcgcgcg gtaacagtga
    42001 aaaaccggtg ttactgtcag tagaaggtca ctttacgctt gaggctaatc cggataccgg
    42061 tgcgccgacc aaagtattag cgcccgatac ggcaggtaaa ttttacccaa accatgattg
    42121 cagtagtttg gggctgtaac ccgtcttgag acagaaacaa atgaaatatt gcctcatgcg
    42181 ctgcgcttat caggcctaaa gcatacaatg caatattttg aattagcaca attttgtagg
    42241 ccggataagg cgttcacgcc gcatccggca ttttgcgcac gaggctggct tttatcactg
    42301 agtcagccca acaaagcggc ctgccttgat ataaatccca ggcttcatgt gcccaacata
    42361 ctgtaactgc gtttctggct taaacgcaga gatatcgcca gtacgcatat gcatcagatc
    42421 ggcagggcta atccagcctg attgcgccag cgtaagcgga tgcccggctt tggcaaatgc
    42481 atcagtgaca aattccgaac aaaaccacga ctttttgtct ccttcgccaa cgttacttaa
    42541 ctgtgctttc gccaggccgc tgacgcactg ttgacgaaaa tcctcggaga atggatttag
    42601 tgagcacatc tggcgagtca ccataaatgg aataaattcg acaatgccgc gatagttgta
    42661 accgctatct ttaattttgt tggcgaacgc ggtgatttct gtggcttgtt gcggggtaag
    42721 atccgggact cgtaagacga aaagcttatc actatgcttt atggcttttt taagggaaac
    42781 aatctggacg ccagcgcctg tcgcttcggc aacgttgtta tctcccaaat agattgcaac
    42841 gtgactcaca gaggaagtgc tgaatacgcg gataccaaat gaggttaccc caaggcttga
    42901 ggagaaaagc aaatcgccgg gtttgagatc tggttccgtt atttctttta ttgattgttc
    42961 ggtgaaagag ctttgatgct ggaatttaac agcccatgtt ttcgcctcgg catttaccac
    43021 tgtggctgat gagtctggct ggctgatatc aacggtacag gccgaaagta caagaaagca
    43081 ggggagaagc aggcggcagt acgcctttgg tttatccatt ttatacaatc catgtaaaaa
    43141 agggccccga aattcaggac cctttctggc atcagccttt aatctgtttc accagataat
    43201 cgacgatgtc accagtctta attaactgtt tctcgccgtt acgacgatat ttatattcga
    43261 tatcatcgtt gtcgaggtta cggtcgccca gcacaatagt gtgcggaata ccgatcagtt
    43321 ccatatcagc aaacatcacg cccggacgct ctttgcggtc atccagcagc acttcgatac
    43381 cttgtgcgcg cagttcgctg tacagtttct cagcaagttc ctgtacgcgg aaggatttgt
    43441 gcatgttcat tggcagaatc gccacctgga acggcgcgat agcgtcaggc catacgatgc
    43501 cgcgttcgtc gtagttctgc tcaatcgccg ctgctaccac acgcgttaca ccgataccgt
    43561 agcaacccat cgtcaggatt tggttacggc catcttcacc ctgtacggag gctttcagtg
    43621 cttcggagta cttggtaccc agctggaaga tgtgaccgac ttcgatacca cgtttgatca
    43681 gcagcgtacc ctgaccatcc gggcttggat cgccagccac cacgttgcgg atatcagcaa
    43741 tttccggggt agcgacatcg cgatcccagt tgataccgaa gtagtgttta ccatcaatgt
    43801 tagcaccagc agcaaaatca ctcatcgcag caacggtacg gtcaatcacc accggaatcg
    43861 gcatgtttac cggacccagt gaacccggac cggctttaac cacggcacga atttcttctt
    43921 cagtcgcaaa agtcagcggg cttgcaacct gcggcagttt ttctgcttta acttcgttca
    43981 gctcgtggtc accgcgcacc agcagcgcaa ccagcgggaa gctactgcct tcaacggctt
    44041 taaccagcag agtcttcacc gttttctcaa tcggcagatt gaactgttca accagttccg
    44101 cgatggtttt cgcgttcggc gtatcaatca gcgtcatttc ctgggtagca gcagcgcgcg
    44161 gttctttcgg cgcgatagct tctgccagct caatgttcgc tgcatagtca gaggtgtcgg
    44221 agaagaccac atcgtcttca ccgctctgcg ccagcacctg gaattcatga gaggcgctac
    44281 cgccgataga accagtgtcg gcctgtacgg cgcggaaatc cagccccatg cggctgaaga
    44341 ttttgctgta ggccgcatac attgcatcgt aggtttcctg cagggattcc tgagaagtat
    44401 ggaaagagta agcatctttc atcaggaatt cgcgggaacg catgacgccg aaacgcggac
    44461 gcacttcgtc gcggaacttg gtctggatct gatagaagtt cagcggcagc tgtttgtaag
    44521 agctcagctc gttacgaatc aggtcagtga taacttcttc atgagttggg ccgagtacga
    44581 acggacggtc accacggtca gcaatacgca gcaattccgg gccatactgt tcccaacgac
    44641 cactctcttg ccacagttca gatggctgaa ccaccggcat taacacctcg atcgcaccgg
    44701 cgttgttcat ctcttcacgc acgatgtttt cgactttttt cagaacgcgc acgccggtcg
    44761 gcagccaggt atataacccg gaggccagct tgcggatcat cccggcgcgc agcatcagct
    44821 gatggctgat cacctcggcg tcggcaggtg tctccttgag agtggagagc aggtattggc
    44881 tagtacgcat gttgttacgg ttccagttgg aaggtagaac aggctcaagg cgagcctggg
    44941 acaaaaaaag tgatttagtt taccagtgca aaagaaatgt caaaagagaa gggcgtgaat
    45001 ttaacgcggt tccagcgcaa agacttcaaa acctgcgtcg gtgacgcgcc agcgaacatt
    45061 aaaatcatgc agccagacgg cataggtttt gcccgtttcc tcacctttac gataggccgg
    45121 gcgcgggtcc tgcgccagta cttcgcggat aaacagcgtt aactgcggat aacgcttctc
    45181 cagcgtcaaa agctgctttt cgacctctgc ggtaaaacac accgccattt ctgccgctgg
    45241 cgcactttgc gcatagctgg cactggcatc gggaagcgat tcggcaaagg ggagatacgg
    45301 tttgatatcc actaccggcg taccatcgac cagatccaga ctgccgagct tcagaatcac
    45361 gctgtcttta tggcaaacaa cctctttcag ctctaccagc gacataccaa ttgggttagg
    45421 gcgaaaagtg gagcgcgtag cgaaaacacc cattctggca ttaccgccaa gacgaggcgg
    45481 acgcacagtc ggacgccagc cgccttccat cgtttgatga aagacgaaaa ggatccataa
    45541 atggctgaat gcttccaggc cgcgaacggc gtcggcctgg ttgtagggtg caatgagatg
    45601 tagttcgccg ttggcgcttt ttaccagacc tggctggcgc ggaacggcga atttttcttt
    45661 atagggcgag cgaataacgc ctatttgctc gaactggaaa ctgctcattt cgccgtgatg
    45721 ttaagcgcag aaccgataca tacagcctga cgatagcagc ctggcgtacc gctggtgact
    45781 tcgcagctat gcagtaatac cgcattggct ttcattttcg aggcgttgat ttgcatccgc
    45841 ttacgtgcgg ttggaatgct cggcggagag tcctgattag aggcctggca agagtcgcca
    45901 ctgacttcac cgagatcgcg gaacggtttg ccgactaatt cttctgcatt ggtataaatt
    45961 cggaccggcg tggcgcgcgg cgctttcggt tttgcaggct ccgctttcgg ctggggtgca
    46021 gtgctttgaa cgggttcgac aggggatctg cttaacatgg aacagccgct tagcatgagt
    46081 gctactaaac agatcggtaa agcacgcata gtatttcctc aatgtatgat caaaacgtca
    46141 atattgaatc aggcgcttgt aaaaatgaca agacgggcaa gcgcccgtcc tgaatgatat
    46201 tacaaattgt ggaaacagcc taaatattac cagcctttaa cagcgccgcc gttaaacact
    46261 ttgtttgctg cttcgtaaac ttcgtcagac tgataagcct gaacgaattt cttcacgttt
    46321 tcggcgtctt tgttgtcttc acgcgttacg atcaggttta cgtacgggga ctctttatct
    46381 tcgacaaaga taccgtcttt cgctggagtc aggccaatct ggctggcata ggtggtattg
    46441 ataactgcca gagcgatttg cgcgtcgtcc agagagcgcg gcagctgcgg tgcttccagt
    46501 tcaacaattt tcagattttt tgggttctca acaacatcaa gaacggtcgg cagcaggcca
    46561 acgccatctt tcagtttgat caagcccact ttttgcagca gcagcagtga acgaccaagg
    46621 ttagttgggt cgtttggcac ggcaacctgc gaaccatcct gcagttcatc cagtgatttg
    46681 attttcttgg agtaacctgc aatcggataa acaaaagtgt tgcctactgc gaccagtttg
    46741 tagccacgat ctttcagttg ctgatcaagg tacggtttat gctggaaggc gttggcgtcg
    46801 atatcgcctt tgctcaatgc ttcgtttggc agaacatagt cgttgaaggt taccagctca
    46861 acgtccaggc catatttgtc tttcgcaact ttctgcgcga cttctgcaac ctgctgttcg
    46921 gcaccaacaa tcacgccgac tttaatgtgg tttggatctt tttcatcctg accgcagcct
    46981 accagtgcca gtgatccaat cagggctccc actgccgcaa aggttttgaa tttgaacgcc
    47041 ataccttatt ccttcttcaa ttatttatgt tgtgttgaac gttacttgcg agtgacagcc
    47101 cggacgatgc ggtcgcctgc gaactgaatt aaataaacca gaatgaccag caataccagt
    47161 accgtattca tcaccgtcgc gttgtagccg atgtagccat actgatagcc aatctgacct
    47221 aaaccaccgg caccgactgc accacccatc gcggaataac cgaccagggt aatcagggtg
    47281 atagtcgcag cattcaccag acccggcaat gcttccggta acagcacttt acggacgatc
    47341 tgcatcggcg tggcacccat tgcgcgggaa gcttcaatta acccggttgg gatctccagc
    47401 agagcgttct cgaccatacg ggcaataaac ggtgctgcac caacggttaa cggaacaatc
    47461 gctgcctgca aaccaatcga tgtaccgaca ataactcggg taaacggaat catccatacc
    47521 agcaagataa tgaacgggat agaacggaaa atgttcacaa tcgcagaaac ggtacgatac
    47581 agcttcgcgt tagcaataat ttgccccgga cgcgtgacat aaagcaggac gccaaccggc
    47641 agaccaatca caaacccaaa aaatccggat acgaaggtca ttgccagcgt ttcccatacg
    47701 ccacgaacca gcagccacat catcggctca gacataaccc agtacctcta cttttacatg
    47761 gtgttcctgc agccaggcaa tggcggcttg cgtatcttgt tgtgtaccgt gcatttcagt
    47821 cagcatgatg ccgaacttaa cgccaccggc gtaatccatc tgcgcactaa taatgttgtt
    47881 gttgacgttg aaacgacgcg cggtttcaga aagcagcggg gcatcaaccg attgaccggt
    47941 aaactccaga cgcagcattg gcacgcagtc agcgaatggt tccgcttgca gacgttcttg
    48001 ataatcttcc gggatatcca gatgcagggt cgactgaata aacttctgcg ccagcggcgt
    48061 tttcggatgc gagaacactt cacttaccgt gtcctgctcg atcaactcgc cattactgat
    48121 caccgccacg caatcacaaa tgcgcttcac aacgtccatt tcgtgggtga tcaacagaat
    48181 cgtcaaaccc agacgacgat tgatgtcttt cagcagttcg agaatagaac gtgtcgttgc
    48241 cgggtccagc gcgctggtgg cttcatcaca cagcaatact ttgggattgc tggctaatgc
    48301 acgggcaatc gccacacgtt gtttctgccc accggaaaga ttcgacgggt agctatcatg
    48361 cttatcgcca agaccaacca atgacagcaa ttccgtcacg cgacgtttga tctcgtcttt
    48421 cggtgtgttg tccagctcca gcggcagagc aacgttgcca aaaacagtac gcgaagagag
    48481 caggttaaaa tgctggaaaa tcataccaat ctggcgacga gctttggtca actcggattc
    48541 tgacagcgtg gtcagttcct ggccatcgac cagcacgcta ccctcggttg ggcgctccag
    48601 caggtttaca caacgtataa gcgtactctt acccgcgcct gaggcaccga taacgccata
    48661 aatttgtcca gctggcacat gcaggctgac gttgttcaac gcctggatgg tgcgggtgcc
    48721 ctggtggaac actttggtga tattcgaaag ttttatcatt gattatttat tatcgtcatt
    48781 aagttagtcg tggcatttcg aatgcctgga acgggcaacg ccgtcaatga aatggatgtt
    48841 aaggcatcca gacgtctaaa tcaatcaggt ttatgcgaag agcactttct tgcaggtcga
    48901 aacatgcgat actagcgtca catgccttat taaggagcta taaaaggtgg cgaagagcgt
    48961 acccgcaatt tttcttgacc gtgatggcac cattaatgtc gatcacggct atgtccatga
    49021 gatcgacaac tttgaattta tcgacggtgt tattgacgcc atgcgcgagc taaaaaaaat
    49081 gggctttgcg ctggtggtag taaccaacca gtctggcatt gctcgcggta aatttactga
    49141 agcacagttt gaaacgctga ccgagtggat ggactggtcg ctggcggacc gcgatgtcga
    49201 tctggatggt atctattatt gcccgcatca tccgcagggt agtgttgaag agtttcgcca
    49261 ggtctgcgac tgccgcaaac cacatccggg gatgctttta tcggcacgcg attatttgca
    49321 tattgatatg gccgcttctt atatggtggg cgataaatta gaagatatgc aggcagcggc
    49381 tgcggcgaac gtgggaacaa aagtgctggt gcgtacgggt aaacctgtta cgcctgaagc
    49441 agaaaacgcg gcggattggg tgttaaatag cctggcagac ctgccgcaag cgataaaaaa
    49501 gcagcaaaaa ccggcgtaat gattaaaaga tgagcggttg aaataaaaat gcatttttcc
    49561 gcttgtcttc ctgagccgac tccctataat gcgcctccat cgacacggcg gatgtgaatc
    49621 acttcacaca aacagccggt tcggttgaag agaaaaatcc tgaaattcag ggttgactct
    49681 gaaagaggaa agcgtaatat acgccacctc gcgacagtga
//
LOCUS       DADXDL010000022        49620 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.022, whole genome shotgun sequence.
ACCESSION   DADXDL010000022 DADXDL010000000
VERSION     DADXDL010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49620
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.022"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(271..888)
                     /gene="tdk"
                     /locus_tag="IRB70_001595"
     CDS             complement(271..888)
                     /gene="tdk"
                     /locus_tag="IRB70_001595"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBC0631520.1"
                     /translation="MAQLYFYYSAMNAGKSTALLQSSYNYQERGMRTVVYTAEIDDRF
                     GAGKVSSRIGLSSPAKLFNQNSSLFDEIRAEHEQQAIHCVLVDECQFLTRQQVYELSE
                     VVDQLDIPVLCYGLRTDFRGELFIGSQYLLAWSDKLVELKTICFCGRKASMVLRLDQA
                     GRPYNEGEQVVIGGNERYVSVCRKHYKEALEVGSLTAIQERHRHD"
     gene            1492..1905
                     /gene="hns"
                     /locus_tag="IRB70_001596"
     CDS             1492..1905
                     /gene="hns"
                     /locus_tag="IRB70_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator H-NS"
                     /protein_id="HBC0631521.1"
                     /translation="MSEALKILNNIRTLRAQARECTLETLEEMLEKLEVVVNERREEE
                     SAAAAEVEERTRKLQQYREMLIADGIDPNELLNSLAAVKSGTKAKRAQRPAKYSYVDE
                     NGETKTWTGQGRTPAVIKKAMDEQGKSLDDFLIKQ"
     gene            complement(2050..2958)
                     /gene="galU"
                     /locus_tag="IRB70_001597"
     CDS             complement(2050..2958)
                     /gene="galU"
                     /locus_tag="IRB70_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBC0631522.1"
                     /translation="MAAINTKVKKAVIPVAGLGTRMLPATKAIPKEMLPLVDKPLIQY
                     VVNECIAAGITEIVLVTHSSKNSIENHFDTSFELEAMLEKRVKRQLLDEVQSICPPHV
                     TIMQVRQGLAKGLGHAVLCAHPVVGDEPVAVILPDVILDEYESDLSQDNLAEMIRRFD
                     ETGHSQIMVEPVADVTAYGVVDCKGVELAPGESVPMVGVVEKPKADVAPSNLAIVGRY
                     VLSADIWPLLAKTPPGAGDEIQLTDAIDMLIEKETVEAYHMKGKSHDCGNKLGYMQAF
                     VEYGIRHNTLGTEFKAWLEEEMGIKK"
     gene            complement(3160..4173)
                     /gene="rssB"
                     /locus_tag="IRB70_001598"
     CDS             complement(3160..4173)
                     /gene="rssB"
                     /locus_tag="IRB70_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator RssB"
                     /protein_id="HBC0631523.1"
                     /translation="MTQPLVGKQILIVEDEQVFRSLLDSWFSSLGATTVLAADGVDAL
                     ELLGGFTPDLMICDIAMPRMNGLKLLEHIRNRGDQTPVLVISATENMADIAKALRLGV
                     EDVLLKPVKDLNRLREMVFACLYPSMFNSRVEEEERLFRDWDAMVDNPAAAAKLLQEL
                     QPPVQQVISHCRVNYRQLVAADKPGLVLDIAALSENDLAFYCLDVTRAGHNGVLAALL
                     LRALFNGLLQEQLAHQNQRLPELGALLKQVNHLLRQANLPGQFPLLVGYYHRELKNLI
                     LVSAGLNATLNTGEHQVQISNGVPLGTLGNAYLNQLSQRCDAWQCQIWGTGGRLRLML
                     SAE"
     gene            complement(4265..5170)
                     /gene="rssA"
                     /locus_tag="IRB70_001599"
     CDS             complement(4265..5170)
                     /gene="rssA"
                     /locus_tag="IRB70_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase RssA"
                     /protein_id="HBC0631524.1"
                     /translation="MRKIKIGLALGSGAARGWSHIGVINALKKVGIEIDIVAGCSIGS
                     LVGAAYACDRLSALEDWVTSFSYWDVLRLMDLSWQRGGLLRGERVFNQYREIMPETEI
                     ENCSRRFAAVATNLSTGRELWFTEGDLHLAIRASCSIPGLMAPVAHNGYWLVDGAVVN
                     PIPISLTRALGADIVIAVDLQHDAHLMQQDLLSFNVSEENSENGDSLPWHARLKERLG
                     SITTRRAVTAPTATEIMTTSIQVLENRLKRNRMAGDPPDILIQPVCPQISTLDFHRAH
                     AAIAAGQLAVEKKMDELLPLVRTNI"
     gene            5283..5741
                     /locus_tag="IRB70_001600"
     CDS             5283..5741
                     /locus_tag="IRB70_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YchJ family protein"
                     /protein_id="HBC0631525.1"
                     /translation="MSQLCPCGSAVEYSLCCHPYVSGEKVAPDPEHLMRSRYCAFVMK
                     DADYLIKTWHPSCGAAALRAELMAGFAHTEWLGLTVFEHCWQDADNIGFVSFVARFTE
                     GGKTGAIIERSRFLKENGQWYYIDGTRPQFGRNDPCPCGSGKKFKKCCGQ"
     gene            5791..6633
                     /gene="purU"
                     /locus_tag="IRB70_001601"
     CDS             5791..6633
                     /gene="purU"
                     /locus_tag="IRB70_001601"
                     /EC_number="3.5.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formyltetrahydrofolate deformylase"
                     /protein_id="HBC0631526.1"
                     /translation="MHSLQRKVLRTICPDQKGLIARITNICYKHELNIVQNNEFVDHR
                     TGRFFMRTELEGIFNDSTLLADLDSALPEGSVRELNPAGRRRIVILVTKEAHCLGDLL
                     MKANYGGLDVEIAAVIGNHDTLRSLVERFDIPFELVSHEGLSRNEHDQKMADAIDAYQ
                     PDYVVLAKYMRVLTPEFVARFPNKIINIHHSFLPAFIGARPYHQAYERGVKIIGATAH
                     YVNDNLDEGPIIMQDVIHVDHTYTAEDMMRAGRDVEKNVLSRALYKVLAQRVFVYGNR
                     TIIL"
     gene            6793..6877
                     /locus_tag="IRB70_001602"
     tRNA            6793..6877
                     /locus_tag="IRB70_001602"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6827..6829,aa:Tyr,seq:gta)
     gene            complement(7061..7738)
                     /gene="narI"
                     /locus_tag="IRB70_001603"
     CDS             complement(7061..7738)
                     /gene="narI"
                     /locus_tag="IRB70_001603"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HBC0631527.1"
                     /translation="MQFLNMFFFDIYPYIAGAVFLIGSWLRYDYGQYTWRAASSQMLD
                     RKGMNLASNLFHIGILGIFVGHFFGMLTPHWMYEAWLPIEVKQKMAMFAGGASGVLCL
                     IGGVLLLKRRLFSPRVRATTTGADILILSLLVIQCALGLLTIPFSAQHMDGSEMMKLV
                     GWAQSVVTFHGGASQHLDGVAFIFRLHLVLGMTLFLLFPFSRLVHIWSVPVEYLTRKY
                     QLVRARH"
     gene            complement(7738..8448)
                     /gene="narJ"
                     /locus_tag="IRB70_001604"
     CDS             complement(7738..8448)
                     /gene="narJ"
                     /locus_tag="IRB70_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HBC0631528.1"
                     /translation="MIELVIVSRLLEYPDAALWQHQQEMFEAIAASKNLSKEDAHALG
                     IFLRDLTAMDPLDAQAQYSELFDRGRATSLLLFEHVHGESRDRGQAMVDLLAQYEQHG
                     LQLNSRELPDHLPLYLEYLAQLPQSEAVEGLKDIAPILALLSARLQQRESRYAVLFDL
                     LLKLANTAIDSDKVAEKIADEARDDTPQALDAVWEEEQVKFFADKGCGDSAITAHQRR
                     FAGAVAPQYLNITTGGQH"
     gene            complement(8445..9983)
                     /gene="narH"
                     /locus_tag="IRB70_001605"
     CDS             complement(8445..9983)
                     /gene="narH"
                     /locus_tag="IRB70_001605"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HBC0631529.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTSREGVEYAWFNNV
                     ETKPGQGFPTDWENQEKYKGGWIRKINGKLQPRMGNRAMLLGKIFANPHLPGIDDYYE
                     PFDFDYQNLHTAPEGSKSQPIARPRSLITGERMAKIEKGPNWEDDLGGEFDKLAKDKN
                     FDNIQKAMYSQFENTFMMYLPRLCEHCLNPACVATCPSGAIYKREEDGIVLIDQDKCR
                     GWRMCITGCPYKKIYFNWKSGKSEKCIFCYPRIEAGQPTVCSETCVGRIRYLGVLLYD
                     ADAIERAASTENEKDLYQRQLDVFLDPNDPKVIEQAIKDGIPLSVIEAAQQSPVYKMA
                     MEWKLALPLHPEYRTLPMVWYVPPLSPIQSAADAGELGSNGILPDVESLRIPVQYLAN
                     LLTAGDTKPVLRALKRMLAMRHYKRAETVDGKVDTRALEEVGLTEAQAQEMYRYLAIA
                     NYEDRFVVPSSHRELAREAFPEKNGCGFTFGDGCHGSDTKFNLFNSRRIDAIDVTSKT
                     EPHP"
     gene            complement(9980..13723)
                     /locus_tag="IRB70_001606"
     CDS             complement(9980..13723)
                     /locus_tag="IRB70_001606"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit alpha"
                     /protein_id="HBC0631530.1"
                     /translation="MSKFLDRFRYFKQKGETFADGHGQLLNTNRDWEDGYRQRWQHDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWETQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPMMRKRLMKMWREAKALHSDPVEAWASIIEDADKAKSFKQARGRGGFVR
                     SSWQEVNELIAASNVYTIKNYGPDRVAGFSPIPAMSMVSYASGARYLSLLGGTCLSFY
                     DWYCDLPPASPQTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTVAVTPDYAEIAKLCDLWLAPKQGTDAAMALAMGHVMLREFHLDNPSQYFTDYVRRY
                     TDMPMLVMLEERDGYYAAGRMLRAADLVDALGQENNPEWKTVAFNTNGEMVVPNGSIG
                     FRWGEKGKWNLEQRDGKTGEETELQLSLLGSQDEIAEVGFPYFGGDGTEHFNKVELEN
                     VLLHKLPVKRLQLADGSTALVTTVYDLTLANYGLERGLNDVNCATSYDDVKAYTPAWA
                     EQITGVSRSQIIRIAREFADNADKTHGRSMIIVGAGLNHWYHLDMNYRGLINMLIFCG
                     CVGQSGGGWAHYVGQEKLRPQTGWQPLAFALDWQRPARHMNSTSYFYNHSSQWRYETV
                     TAEELLSPMADKSRYTGHLIDFNVRAERMGWLPSAPQLGTNPLTIAGEAEKAGMNPVD
                     YTVKSLKEGSIRFAAEQPENGKNHPRNLFIWRSNLLGSSGKGHEFMLKYLLGTEHGIQ
                     GKDLGQQGGVKPEEVDWQDNGLEGKLDLVVTLDFRLSSTCLYSDIILPTATWYEKDDM
                     NTSDMHPFIHPLSAAVDPAWEAKSDWEIYKAIAKKFSEVCVGHLGKETDIVTLPIQHD
                     SAAELAQPLDVKDWKKGECDLIPGKTAPHIMVVERDYPATYERFTSIGPLMEKIGNGG
                     KGIAWNTQSEMDLLRKLNYTKAEGPAKGQPMLNTAIDAAEMILTLAPETNGQVAVKAW
                     AALSEFTGRDHTHLALNKEDEKIRFRDIQAQPRKIISSPTWSGLEDEHVSYNAGYTNV
                     HELIPWRTLSGRQQLYQDHQWMRDFGESLLVYRPPIDTRSVKEVMGQKSNGNPEKALN
                     FLTPHQKWGIHSTYSDNLLMLTLGRGGPVVWLSEADAKDLGIADNDWIEVFNSNGALT
                     ARAVVSQRVPAGMTMMYHAQERIVNLPGSEITQQRGGIHNSVTRITPKPTHMIGGYAH
                     LAYGFNYYGTVGSNRDEFVVVRKMKNIDWLDGEGNDQVQESVK"
     gene            complement(14116..15507)
                     /gene="narK"
                     /locus_tag="IRB70_001607"
     CDS             complement(14116..15507)
                     /gene="narK"
                     /locus_tag="IRB70_001607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate transporter NarK"
                     /protein_id="HBC0631531.1"
                     /translation="MSHSSAPERATGAVITDWRPEDPAFWQQRGQRIASRNLWISVPC
                     LLLAFCVWMLFSAVAVNLPKVGFNFTTDQLFMLTALPSVSGALLRVPYSFMVPIFGGR
                     RWTAFSTGILIIPCVWLGFAVQDTATPYSVFIIISLLCGFAGANFASSMANISFFFPK
                     QKQGGALGLNGGLGNMGVSVMQLVAPLVVSLSIFAVFGSQGVKQPDGTELYLANASWV
                     WVPFLAIFTIAAWFGMNDLATSKASIKEQLPVLKRGHLWIMSMLYLATFGSFIGFSAG
                     FAMLSKTQFPDVQILQYAFFGPFIGALARSAGGALSDRLGGTRVTLVNFILMAIFSGL
                     LFLTLPTDGQGGSFMAFFAVFLALFLTAGLGSGSTFQMISVIFRKLTMDRVKAEGGSD
                     ERAMREAATDTAAALGFISAIGAIGGFFIPKAFGSSLALTGSPVGAMKVFLIFYIACV
                     VITWAVYGRHSKK"
     gene            15846..17642
                     /gene="narX"
                     /locus_tag="IRB70_001608"
     CDS             15846..17642
                     /gene="narX"
                     /locus_tag="IRB70_001608"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite two-component system sensor
                     histidine kinase NarX"
                     /protein_id="HBC0631532.1"
                     /translation="MLKRCLSPLTLVNQVALIVLLSTAIGLAGMAVSGWLVQGVQGSA
                     HAINKAGSLRMQSYRLLAAVPLSEKDKPLIKEMEQTAFSAELTRAAERDGQLAQLQGL
                     QDYWRNELIPALMRAQNRETVSADVSQFVAGLDQLVSGFDRTTEMRIETVVLVHRVMA
                     VFMALLLVFTIIWLRARLLQPWRQLLAMASAVSHRDFTQRANISGRNEMAMLGTALNN
                     MSAELAESYAVLEQRVQEKTAGLEHKNQILSFLWQANRRLHSRAPLCERLSPVLNGLQ
                     NLTLLRDIELRVYDTDDEENHQEFTCQPDMTCDDKGCQLCPRGVLPVGDRGTTLKWRL
                     ADSHTQYGILLATLPQGRHLSHDQQQLVDTLVEQLTATLALDRHQERQQQLIVMEERA
                     TIARELHDSIAQSLSCMKMQVSCLQMQGDALPESSRELLSQIRNELNASWAQLRELLT
                     TFRLQLTEPGLRPALEASCEEYSAKFGFPVKLDYQLPPRLVPSHQAIHLLQIAREALS
                     NALKHSQASEVVVTVAQNDNQVKLTVQDNGCGVPENAIRSNHYGMIIMRDRAQSLRGD
                     CRVRRRESGGTEVVVTFIPEKTFTDVQGDTHE"
     gene            17635..18285
                     /gene="narL"
                     /locus_tag="IRB70_001609"
     CDS             17635..18285
                     /gene="narL"
                     /locus_tag="IRB70_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator NarL"
                     /protein_id="HBC0631533.1"
                     /translation="MSNQEPATILLIDDHPMLRTGVKQLISMAPDITVVGEASNGEQG
                     IELAESLDPDLILLDLNMPGMNGLETLDKLREKSLSGRIVVFSVSNHEEDVVTALKRG
                     ADGYLLKDMEPEDLLKALHQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRE
                     RDILKLIAQGLPNKMIARRLDITESTVKVHVKHMLKKMKLKSRVEAAVWVHQERIF"
     gene            complement(18286..19680)
                     /gene="ychO"
                     /locus_tag="IRB70_001610"
     CDS             complement(18286..19680)
                     /gene="ychO"
                     /locus_tag="IRB70_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415738.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter invasin YchO"
                     /protein_id="HBC0631534.1"
                     /translation="MSRFVPRIIPFYLLLLAAGGTANAQSTFEQKAANPFDNNNDGLP
                     DLGMAPENHDGEKHFAEIVKDFGETSMNDNGLDTGEQAKAFALGKVRDALSQQVNQHV
                     ESWLSPWGNASVDVKVDNEGHFTGSRGSWFVPLQDNDRYLTWSQLGLTQQDDGLVSNV
                     GVGQRWARGNWLVGYNTFYDNLLDENLQRAGFGAEAWGEYLRLSANFYQPFAAWHEQT
                     ATQEQRMARGYDLTARMRMPFYQHLNTSVSVEQYFGDRVDLFNSGTGYHNPVALSLGL
                     NYTPVPLVTVTAQHKQGESGENQNNLGLNLNYRFGVPLKKQLSAGEVAESQSLRGSRY
                     DNPQRNNLPTLEYRQRKTLTVFLATPPWDLKPGETVPLKLQIRSRYGIRQLIWQGDTQ
                     ILSLTPGAQANSVEGWTLIMPDWQNGEGASNHWRLSVVVEDNQGQRVSSNEITLTLVE
                     PFDALSNDELRWEP"
     gene            19865..20218
                     /gene="ychN"
                     /locus_tag="IRB70_001611"
     CDS             19865..20218
                     /gene="ychN"
                     /locus_tag="IRB70_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE/F sulfur relay family protein YchN"
                     /protein_id="HBC0631535.1"
                     /translation="MQKIVIVANGAPYGSESLFNSLRLAIALREQENNLDLRLFLMSD
                     AVTAGLRGQKPGEGYNIQQMLEILTAQNVPVKLCKTCTDGRGISTLPLIDGVEIGTLV
                     ELAQWTLSADKVLTF"
     gene            complement(20262..20957)
                     /gene="chaC"
                     /locus_tag="IRB70_001612"
     CDS             complement(20262..20957)
                     /gene="chaC"
                     /locus_tag="IRB70_001612"
                     /EC_number="4.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415736.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-specific
                     gamma-glutamylcyclotransferase"
                     /protein_id="HBC0631536.1"
                     /translation="MITRDFLMNADCKTAFGAIEESLLWSAEQRAASLAATLACRPDE
                     GPVWIFGYGSLMWNPALEFTESCTGTLVGWHRAFCLRLTAGRGTAHQPGRMLALKEGG
                     RTTGVAYRLPEETLEQELTLLWKREMITGCYLPTWCQLDLDDGRTVNAIVFIMDPRHP
                     EYESDTRAQVIAPLIAAASGPLGTNAQYLFSLEQELIKLGMQDDGLNDLLVSVKKLLA
                     ENYPDAVLRPGFA"
     gene            complement(21115..21345)
                     /gene="chaB"
                     /locus_tag="IRB70_001613"
     CDS             complement(21115..21345)
                     /gene="chaB"
                     /locus_tag="IRB70_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative cation transport regulator ChaB"
                     /protein_id="HBC0631537.1"
                     /translation="MPYKTKSDLPESVKHVLPSHAQDIYKEAFNSAWDQYKDKEDRRD
                     DASREETAHKVAWAAVKHEYAKGDDDKWHKKS"
     gene            21615..22715
                     /gene="chaA"
                     /locus_tag="IRB70_001614"
     CDS             21615..22715
                     /gene="chaA"
                     /locus_tag="IRB70_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium-potassium/proton antiporter ChaA"
                     /protein_id="HBC0631538.1"
                     /translation="MSNAQEAVKTRHKETSLIFPVLALVVLFLWGSSQTLPVVIAINL
                     LALIGILSSAFSVVRHADVLAHRLGEPYGSLILSLSVVILEVSLISALMATGDAAPTL
                     MRDTLYSIIMIVTGGLVGFSLLLGGRKFATQYMNLFGIKQYLIALFPLAIIVLVFPMA
                     LPAANFSTGQALLVALISAAMYGVFLLIQTKTHQSLFVYEHEDDSDDDDPHHGKPSAH
                     SSLWHAIWLIIHLIAVIAVTKMNASPLETLLDSMNAPVAFTGFLVALLILSPEGLGAL
                     KAVLNNQVQRAMNLFFGSVLATISLTVPVVTLIAFMTGNELQFALGAPEMVVMVASLV
                     LCHISFSTGRTNVLNGAAHLALFAAYLMTIFA"
     gene            23120..23227
                     /locus_tag="IRB70_001615"
     CDS             23120..23227
                     /locus_tag="IRB70_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HBC0631539.1"
                     /translation="MTLAQFAMIFWHDLAAPILAGIITAVIVSWWRNRK"
     gene            23655..23762
                     /locus_tag="IRB70_001616"
     CDS             23655..23762
                     /locus_tag="IRB70_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_025297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin Ldr family
                     protein"
                     /protein_id="HBC0631540.1"
                     /translation="MTLAQFAMTFWHDLAAPILAGIITAVIVSWWRNRK"
     gene            complement(23911..24765)
                     /gene="kdsA"
                     /locus_tag="IRB70_001617"
     CDS             complement(23911..24765)
                     /gene="kdsA"
                     /locus_tag="IRB70_001617"
                     /EC_number="2.5.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-8-phosphooctulonate synthase"
                     /protein_id="HBC0631541.1"
                     /translation="MKQKVVSIGDINVANDLPFVLFGGMNVLESRDLAMRICEHYVTV
                     TQKLGIPYVFKASFDKANRSSIHSYRGPGLEEGMKIFQELKQTFGVKIITDVHEPSQA
                     QPVADVVDVIQLPAFLARQTDLVEAMAKTGAVINVKKPQFVSPGQMGNIVDKFKEGGN
                     EKVILCDRGANFGYDNLVVDMLGFSIMKKVSGNSPVIFDVTHALQCRDPFGAASGGRR
                     AQVAELARAGMAVGLAGLFIEAHPDPEHAKCDGPSALPLAKLEPFLKQMKAIDDLVKG
                     FEELDTSK"
     gene            complement(24801..25610)
                     /locus_tag="IRB70_001618"
     CDS             complement(24801..25610)
                     /locus_tag="IRB70_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat-containing protein"
                     /protein_id="HBC0631542.1"
                     /translation="MRSLADFEFNKAPLCEGMILACEAIRRDFPSQDVYDELERLVSL
                     AKEEISQLLPLEEQLEKLIALFYGDWGFKASRGVYRLSDALWLDQVLKNRQGSAVSLG
                     AVLLWVANRLDLPLLPVIFPTQLILRFECPDGEIWLINPFNGESLSEHMLDVWLKGNI
                     SPSAELFYEDLDEADNIEVIRKLLDTLKASLMEENQMELALRTSEALLQFNPEDPYEI
                     RDRGLIYAQLDCEHVALNDLSYFVEQCPEDPISEMIRVQINNIAHKHIVLH"
     gene            complement(25614..26006)
                     /locus_tag="IRB70_001619"
     CDS             complement(25614..26006)
                     /locus_tag="IRB70_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SirB family protein"
                     /protein_id="HBC0631543.1"
                     /translation="MTSFSTLLSVHLISIALSVGLLTLRFWLRYQKHPQAFARWTRIV
                     PPVVDTLLLLSGIALMAKAHILPFSGQAQWLTEKLFGVIIYIVLGFIALDYRRMHSQQ
                     ARIIAFPLALVVLYIIIKLATTKVPLLG"
     gene            complement(26003..26836)
                     /gene="prmC"
                     /locus_tag="IRB70_001620"
     CDS             complement(26003..26836)
                     /gene="prmC"
                     /locus_tag="IRB70_001620"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBC0631544.1"
                     /translation="MEYQHWLREAISQLQASESPRRDAEILLAHVTGKGRTFILAFGE
                     TQLTDEQCQQLDALLTRRRDGEPIAHLTGVREFWSLPLFVSPATLIPRPDTECLVEQA
                     LARLPEQPCRILDLGTGTGAIALALASERPDCEITAVDRMPDAVSLAQRNAQNLAIKN
                     IHILQSDWFSALAGQQFAMIVSNPPYIDEQDPHLQQGDVRFEPLTALVAADSGMADIV
                     HIIEQSRNALVSGGFLLLEHGWQQGEAVRQAFIHAGYHDVETCRDYGDNERVTLGRYY
                     Q"
     gene            complement(26836..27918)
                     /gene="prfA"
                     /locus_tag="IRB70_001621"
     CDS             complement(26836..27918)
                     /gene="prfA"
                     /locus_tag="IRB70_001621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBC0631545.1"
                     /translation="MKPSIVAKLEALHERHEEVQALLGDAQTIADQERFRALSREYAQ
                     LSDVSRSFTDWQQVQEDIETAQMMLDDPEMREMAQDELREAKEKSEQLEQQLQVLLLP
                     KDPDDERNAFLEVRAGTGGDEAALFAGDLFRMYSRYAEARRWRVEIMSASEGEHGGYK
                     EIIAKISGDGVYGRLKFESGGHRVQRVPATESQGRIHTSACTVAVMPELPDAELPDIN
                     PADLRIDTFRSSGAGGQHVNTTDSAIRITHLPTGIVVECQDERSQHKNKAKALSVLGA
                     RIHAAEMAKRQQAEASTRRNLLGSGDRSDRNRTYNFPQGRVTDHRINLTLYRLDEVME
                     GKLDMLIEPIIQEHQADQLAALSEQE"
     gene            complement(27960..29216)
                     /gene="hemA"
                     /locus_tag="IRB70_001622"
     CDS             complement(27960..29216)
                     /gene="hemA"
                     /locus_tag="IRB70_001622"
                     /EC_number="1.2.1.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_041689438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA reductase"
                     /protein_id="HBC0631546.1"
                     /translation="MTLLALGINHKTAPVSLRERVSFSPDKLEQALDSLLAQPMVQGG
                     VVLSTCNRTELYLSVEERDDLQEALIRWLCDYHNLNEDDLRNSLYWHQDNDAVSHLMR
                     VASGLDSLVLGEPQILGQVKKAFADSQKGHMKARELERMFQKSFSVAKRVRTETDIGA
                     SAVSVAFAACTLARQIFESLSTVTVLLVGAGETIELVARHLREHKVQKMIIANRTRER
                     AQILADEVGAEVIALSDIDERLREADIIISSTASPLPIIGKGMVERALKSRRNQPMLL
                     VDIAVPRDVEPEVGKLANAYLYSVDDLQSIISHNLAQRKAAAVEAETIVAQETSEFMA
                     WLRAQSASETIREYRSQAEHVRDELTAKALAALEQGGDAQAIMQDLAWKLTNRLIHAP
                     TKSLQQAARDGDNERLNILRDSLGLE"
     gene            29430..30053
                     /gene="lolB"
                     /locus_tag="IRB70_001623"
     CDS             29430..30053
                     /gene="lolB"
                     /locus_tag="IRB70_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein localization protein LolB"
                     /protein_id="HBC0631547.1"
                     /translation="MPLPDFRLIRLLPLAALVLTACSVTTPKGPGKSPDSPQWRQHQQ
                     DVRNLNQYQTRGAFAYISDQQKVYARFFWQQTGQDRYRLLLTNPLGSTELELNAQPGN
                     VQLVDNKGQRYTADDAEEMIGKLTGMPIPLNSLRQWILGLPGDATDYKLDDQYRLSEI
                     TYSQNGKNWKVVYGGYDTKTQPAMPANMELTDGGQRIKLKMDNWIVK"
     gene            30053..30904
                     /gene="ispE"
                     /locus_tag="IRB70_001624"
     CDS             30053..30904
                     /gene="ispE"
                     /locus_tag="IRB70_001624"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBC0631548.1"
                     /translation="MRTQWPSPAKLNLFLYITGQRADGYHTLQTLFQFLDYGDTINIE
                     LRDDGDIRLLTPVEGVEHEDNLIVRAARLLMKTAADSGRLPTGSGANISIDKRLPMGG
                     GLGGGSSNAATVLVALNHLWQCGLSMDELAEMGLTLGADVPVFVRGHAAFAEGVGEIL
                     TPVDPPEKWYLVAHPGVSIPTPVIFKDPELPRNTPKRSIETLLKCEFSNDCEVIARKR
                     FREVDAVLSWLLEYAPSRLTGTGACVFAEFDTESEARQVLEQAPEWLNGFVAKGVNLS
                     PLHRAML"
     gene            31055..32002
                     /gene="prs"
                     /locus_tag="IRB70_001625"
     CDS             31055..32002
                     /gene="prs"
                     /locus_tag="IRB70_001625"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBC0631549.1"
                     /translation="MPDMKLFAGNATPELAQRIANRLYTSLGDAAVGRFSDGEVSVQI
                     NENVRGGDIFIIQSTCAPTNDNLMELVVMVDALRRASAGRITAVIPYFGYARQDRRVR
                     SARVPITAKVVADFLSSVGVDRVLTVDLHAEQIQGFFDVPVDNVFGSPILLEDMLQLN
                     LDNPIVVSPDIGGVVRARAIAKLLNDTDMAIIDKRRPRANVSQVMHIIGDVAGRDCVL
                     VDDMIDTGGTLCKAAEALKERGAKRVFAYATHPIFSGNAANNLRNSVIDEVVVCDTIP
                     LSDEIKSLPNVRTLTLSGMLAEAIRRISNEESISAMFEH"
     gene            32127..33806
                     /gene="dauA"
                     /locus_tag="IRB70_001626"
     CDS             32127..33806
                     /gene="dauA"
                     /locus_tag="IRB70_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylic acid transporter DauA"
                     /protein_id="HBC0631550.1"
                     /translation="MNKIFSSHVMPFRALIDACWKEKYTAARFTRDLIAGITVGIIAI
                     PLAMALAIGSGVAPQYGLYTAAVAGIVIALTGGSRFSVSGPTAAFVVILYPVSQQFGL
                     AGLLVATLLSGIFLILMGLARFGRLIEYIPVSVTLGFTSGIGITIGTMQIKDFLGLQM
                     AHVPEHYLQKVGALFMALPTINVGDAAIGIVTLGILVFWPRLGIRLPGHLPALLAGCA
                     VMGIVNLLGGHVATIGSQFHYVLADGSQGNGIPQLLPQLVLPWDLPDSEFTLTWDSIR
                     TLLPAAFSMAMLGAIESLLCAVVLDGMTGTKHKANSELVGQGLGNIIAPFFGGITATA
                     AIARSAANVRAGATSPISAVIHSILVILALLVLAPLLSWLPLSAMAALLLMVAWNMSE
                     AHKVVDLLRHAPKDDIIVMLLCMSLTVLFDMVIAISVGIVLASLLFMRRIARMTRLAP
                     VVVDVPDDVLVLRVIGPLFFAAAEGLFTDLESRLEGKRIVILKWDAVPVLDAGGLDAF
                     QRFVKRLPEGCELRVCNVEFQPLRTMARAGIQPIPGRLAFFPNRRAAMADL"
     gene            complement(33861..34139)
                     /gene="ychH"
                     /locus_tag="IRB70_001627"
     CDS             complement(33861..34139)
                     /gene="ychH"
                     /locus_tag="IRB70_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress-induced protein YchH"
                     /protein_id="HBC0631551.1"
                     /translation="MKRKNASLLGNVLMGLGLVVMVVGVGYSILNQLPQFNMPQYFAH
                     GAVLSIFVGAILWLAGARVGGHEQVCDRYWWVRHYDKRCRRSDNRRHS"
     gene            34417..35001
                     /gene="pth"
                     /locus_tag="IRB70_001628"
     CDS             34417..35001
                     /gene="pth"
                     /locus_tag="IRB70_001628"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBC0631552.1"
                     /translation="MTIKLIVGLANPGAEYAATRHNAGAWFVDLLAERLRAPLREEAK
                     FFGYTSRVTLGGEDVRLLVPTTFMNLSGKAVAAMASFFRINPDEILVAHDELDLPPGV
                     AKFKLGGGHGGHNGLKDIISKLGNNPNFHRLRIGIGHPGDKNKVVGFVLGKPPVSEQK
                     LIDEAIDEAARCTEMWFTDGLTKATNRLHAFKAQ"
     gene            35118..36209
                     /gene="ychF"
                     /locus_tag="IRB70_001629"
     CDS             35118..36209
                     /gene="ychF"
                     /locus_tag="IRB70_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001538644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBC0631553.1"
                     /translation="MGFKCGIVGLPNVGKSTLFNALTKAGIEAANFPFCTIEPNTGVV
                     PMPDPRLDQLAEIVKPQRTLPTTMEFVDIAGLVKGASKGEGLGNQFLTNIRETEAIGH
                     VVRCFENDNIIHVSGKVNPADDIEVINTELALADLDTCERAIHRVQKKAKGGDKDAKA
                     ELAVLEKCLPQLENAGMLRALDLSAEEKAAIRYLSFLTLKPTMYIANVNEDGFENNPY
                     LDQVREIAAKEGSVVVPVCAAVEADIAELDDEERDEFMQELGLEEPGLNRVIRAGYKL
                     LNLQTYFTAGVKEVRAWTIPVGATAPQAAGKIHTDFEKGFIRAQTISFEDFITYKGEQ
                     GAKEAGKMRAEGKDYIVKDGDVMNFLFNV"
     gene            36423..37598
                     /locus_tag="IRB70_001630"
     CDS             36423..37598
                     /locus_tag="IRB70_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HBC0631554.1"
                     /translation="MLTDTQCRTAKAKEKLYRLNDFNGLYLEVKPNGKKAWRYRFKLN
                     GKSSMFALGEYPTVKLAEAREKCEQARKQVADGVSPTQARQLNKIRKVNDASNTFELI
                     AKEWLQMKDWAEITKTRRLDMLERVVFPAIGKLPVREITPHHILKILQETAKRGAPTV
                     AAEARRTISSVFELAVATLRADSDPVWPVRKALPANKTQHKQALNPQQIGKLLSCFDN
                     SRGSYQVNYCMWLMWWTLARPAETTEAEWIEFDLDNALWTIPAARMKARREHVIPLPS
                     QAVKTLRTLQGLTGHRQHLFPGRDNPKGPMTSHSLRQLLKSFGWSGIYSPHATRTTGS
                     TRLNEMGYRPDAIEAQLAHADTNNVRRTYNHATYLDERKVMMQEWSDMLDKWVAGSE"
     gene            37906..38793
                     /locus_tag="IRB70_001631"
     CDS             37906..38793
                     /locus_tag="IRB70_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631555.1"
                     /translation="MDARYEEKTFESYFNNELDRKTSIYFPLGQVQEGVLGLDSVAHS
                     RGWFLWRKLGYPFWLSPQFSGVELREIAHEMEHYLGREVKNIPTMKVNLLFQYKRPQY
                     ITMSSGSEWHLWNQKYFRYDLYTQQHTLLSHIETKFGNDAVVLYAAPSVVDVGDLVNL
                     KRAGSIIDHTNFRRARELDGHHRNTYIKAGTYSQACSEPEMIENFNLIEMIEAMEPRQ
                     SEDNVNLIINFSRQINSAMKDVEGIGYLKTAFENRMDEFRDYGLQQFVLFYSMLTMAI
                     FREVTGCQWLIPFDGRKNA"
     gene            complement(39755..40003)
                     /locus_tag="IRB70_001632"
     CDS             complement(39755..40003)
                     /locus_tag="IRB70_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016154436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631556.1"
                     /translation="MNHPEIHVKDWIDVGNRECVVQRLLPPGSPVGACIVVLNKTKPT
                     TRIAGWNGEKWYFMPSHDFGGYADEYDPCVRELNRGRR"
     gene            complement(40285..42423)
                     /locus_tag="IRB70_001633"
     CDS             complement(40285..42423)
                     /locus_tag="IRB70_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000350636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBC0631557.1"
                     /translation="MEIEINCCNNIDKANITLAVKKLNIKFAPNGTGKSTISRAIQCT
                     VNGDEQGLSDLLPFRYRGSNPDAVQPRVTGVDGLQNVMCFNEKYVDQFTFQPDELVSN
                     SFDIFIKSEAYHETEREIEAMVVAIRQQFADNVGLEEFITHLGELSAAFKLSSTGIAK
                     TSTGMKGLSAGNKLQHIPDGLESYKPYIQSKSSVEWIEWQTRGYEKFSALSDGCCPFC
                     TGDSREKAEQISRVSAEYDKAVIKNLIGLIGVLDKLGEYFSESARARLTDITTLKSGL
                     EKQHEEYLVTVKKQTDSLINMLNTLKTLNGFTFSASTNVKAALEACRLDVKFFPELQS
                     DKTARTVASLNTSLDDLTTQAGRLQGQINKQRQGMQKLILKHKTDINTFLAYAGYRYQ
                     VDITGEGDKCRLKLRHEDFEGYVSGGSQHLSYGERNAFAIVLFMYECLAKKPGLIILD
                     DPISSFDKNKKFAILEMLFRRNTGECLKNETVLMLTHDVEPIIDTLKSVRKLFSNLVT
                     ASHLRYCAGCITEQLIGESDIRTFAQICQSVTDSDSEDIIKLIYLRRHYEIMDDLGDA
                     YQVLSNLFHHRETPIDTREPVVQGVGHPEMSAEKVASGCQAIADRIPGFDYQATFVQL
                     TDPDRIRALYLLCRNGYEKLQVFRLLQTGVENAVIRKFMNETYHIENEFICQLDPARF
                     DLIPEYVIRECDALILPPPPANDDALEEIA"
     gene            42677..42922
                     /locus_tag="IRB70_001634"
     CDS             42677..42922
                     /locus_tag="IRB70_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008103203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0631558.1"
                     /translation="MQKKAVFQCPGEGKSISTLAREFDTARQTFLRVKAAMEEADARS
                     WAALQCMSASCQERTLLKETDNNKWVELVTLTTVLQL"
     gene            42969..43877
                     /locus_tag="IRB70_001635"
     CDS             42969..43877
                     /locus_tag="IRB70_001635"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631559.1"
                     /translation="MRDDFSNKIKQRLAERVAWLCSNPDCRVVTVGPHTDPTKRVNVG
                     QACHIEAASEGGPRYNKEMQKDQRCSFDNGIWLCSIHAKEIDVDPDRFSVELLRKWKL
                     TAEQYALSKVGKARYDVSQDVFTENVNRHRELFSGIRDIEYFSLYRDSNDKCFTLRGV
                     GPLNIIVKDRRIDIFFKDSFNPIKYRNDSYIGLICLPVKELIDYVVLSHEFDETIESF
                     NMTFNFSPNSLNEMYFSIHTDTVNVNPHMDGISYYGDYTVEMDELIDDLGRAIPPYRQ
                     DIYLKIIVAMYNIYRRIVTYKTEGFT"
     gene            complement(44312..49081)
                     /locus_tag="IRB70_001636"
     CDS             complement(44312..49081)
                     /locus_tag="IRB70_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015584083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBC0631560.1"
                     /translation="MKSHEDGLTEQEKEWFYALMQDRADNANTLEKPSMRGIQRSVVD
                     KYSDQAHFIYELLQNADDVRATSVSFRLDQDGLYFIHNGSIHFSVSDPHCEGEDAGNG
                     ALGHINSITSIANSSKTEASIGKFGVGFKAVFQYTQTPHIYDPGIRFKIERFIVPQML
                     NADLDWRNASDTVFFFPFDHKEKTPLESYNEIFEKLKALEFPVLFLSTLKSVSFTVGE
                     TTGRYTKKIVEELEQEDILAQKLVLTLEVGDSKAIHQLLLFTHNHANRNACTIGYAIG
                     EDGKLEPVEHPAFCFFPTKEITHLKFILHAPFLLTDSREGIKAGEKHNQQLIQQLAKL
                     TADSLPIIRDKKLLDDGIFDIIPYDENQFSELDDRRKISFKPFYSAIKTKLQTDTLLP
                     AANANYSPKNCSYWAADSELVELFSDMQLAQLTGTENASWIFRSRGKKDVQNVNKALA
                     EYIDGGDARVWSIREPNLIVSSLDPEATLKKITADFIASQSIEWLHRLYIYLAGRDSY
                     QKFVKDKPIFLDQQGQAIPAFDAWNQLILFLPDDDIDGYKTVNAELLSDESTREFIEK
                     FGIKKPSLRDEIYNKILPAYNSTSSPVNADTHFGRFFRYFKECKNEDVSEFIKLIKDK
                     AFLLYTTAGKNEFSHGKADDIYMPTEDLQTWFTTKPETPFLFLDKYHEMFSEKEYPAL
                     KDFFKKLGIADRPKIITEERYIEWQERRDRHLSLEGHSHKLYEKNLDGCQQIMANIDL
                     PRSLLLWKLLPQFIHQLSGKHVWFYYTNRSESYESAEQEKLRTTRWILDKDGAWVSAK
                     EITIQTLAEQYDIVSAEAKMLINFLHIRDETHLSPEEARKIRLADAIEHSGLSEDEIR
                     IAIEDAKRKKQDSSQPIVEPVDKDQPAADSPFIRDIARRRPSIQDTHSDGPQKDDSAA
                     ADRQSDESIDTDDYTPKTVDYGKKIDLAKDRYASEIDCLEHEQTLYDKANELPRYSYG
                     WFLALLELECLATRTKNADSKTISIGFGKVEHDEQSSRTIVLKEPSRFIPQSIEELSG
                     IRVDLDFGNGRTGKLHIESFTAREFSLLGKLESADDLQGMALEEVVEARIEVQNPSFL
                     QQVLLERFQELRLGETFAMKAGLTSDIDFVFGPPGTGKTTHLAEKVLIPRMKGSGKEN
                     VLVLAPTNKAADVLTTRVMEAMVGDTSYQEWLVRFGSSVDVRIENAGVWRDRTFNIGA
                     LDRSITITTIARFAYDGFTGEYGKKLYEMEWDTVVIDEASMISLANIIYPLYRIHPRK
                     FIIAGDPFQIGPIVAVEEWKDENIYTLVGLNKRGSFAQPSTEPHDYPIVNLETQYRSI
                     PAIGEVYSRFTYDGILQHHRTAESPCSFSFCEFDAMPINLIKFPVSKYESIYRAKRME
                     SGTPYQTYSALFTFEFVRWLSGKIQRKNSEIIRIGVIAPYRAQANLLSKLNDSWLTKP
                     DTVNVQVGTIHGFQGDECNIIIAVLNPPPNISSDSRMFLNKQNILNVAISRARDNLFI
                     VMPDAETENIGNLRKVTEIERLVKASDAYYEYGSNEIEKMIWGNARYLEENIFSTGHQ
                     MVNVYRKPERYYEVRSDDSAIDIQIHEKQSGSKSQIP"
BASE COUNT        12515 a        12511 c        11951 g        12643 t
ORIGIN      
        1 cttctggggc cgtttttttg ttttacccaa agcaactttc ccataaaccg acagcattgt
       61 ccttcatcat atttgcgacg atgtataacg cctacacaca gcgatattgt actttacagg
      121 ttacaagtca atgtcggtgt ataagcgctc tgtgaggggt atagtggcgt taaagaactg
      181 tcgagaaggg tatatacacc ggatgaagtg agtaaaacga actgacagga taaaagcgcc
      241 ctgctcaccc tgtcagtaaa gaaattctta ttaatcgtgg cgatgccttt cctgaatagc
      301 cgttaatgag ccgacttcta acgcttcttt atagtgttta cggcatacag aaacgtagcg
      361 ttcattacca ccaataacca cctgctcacc ttcgttataa ggtctgcctg cttgatcaag
      421 acgcagcacc atgcttgctt tgcggccaca aaaacagatg gtttttaatt caaccagttt
      481 gtcggaccat gccagtaagt attggctgcc aataaataac tcacctcgaa aatcggtacg
      541 taaaccataa caaagtacgg gtatatcgag ttgatcgaca acctccgata attcatatac
      601 ttgttgtctg gttaaaaact ggcattcatc aaccagtacg caatgaattg cctgctgttc
      661 atgttccgca cgaatctcat caaataatga tgaattttgg ttaaataatt ttgcaggcga
      721 tgacaaacct atacgcgagc tgactttccc ggcaccaaag cgatcatcaa tttctgccgt
      781 atatacgaca gtgcgcatgc cgcgttcctg gtaattgtat gaagattgca acaatgctgt
      841 agacttaccc gcattcattg cggaatagta gaaatatagc tgtgccatca gccacaggcc
      901 ctcaatgata tgaattaaag ttggctggag tttatcataa ttcgtcagtt ttacagctca
      961 acagtatgca cagaagtggt atatgcgttc tcccttacga agccttgcat aatccttctg
     1021 agctatcatt acaactgcct cgcttgttat aagcgggtaa atgactgctg gtaactattc
     1081 acaatcttta acctgttgcg caagtaatag ccctctgttg acctcctgga gatagtgcaa
     1141 tactaagtcc ctgctcttat tgcgactgtt ctacttttca tcattcgctt aatagggaat
     1201 tctcgtaaac acgactaata cagaagactg aaaggtcgtc agcctacgat aatctcccca
     1261 taaaatgtga catgaatcag gaagttttaa cctcacgtgc tgcgaaatca tcggtgcaaa
     1321 tagggctata tgccgcgtct tttctggcta attttatgaa aagatattta ttggcggcac
     1381 aaaataaaga acaattttga attccttaca ttcctggcta ttgcacaact gaatttaagg
     1441 ctctattatt acctcaacaa accaccccaa tataagtttg agattactac aatgagcgaa
     1501 gcacttaaaa ttctgaacaa catccgtact cttcgtgcgc aggcaagaga atgtacactt
     1561 gaaacgctgg aagaaatgct ggaaaaatta gaagttgttg ttaacgaacg tcgcgaagaa
     1621 gaaagcgcgg ctgctgctga agttgaagag cgcactcgta aactgcagca atatcgcgaa
     1681 atgctgatcg ctgacggtat tgacccgaac gaactgctga atagccttgc tgccgttaaa
     1741 tctggcacca aagctaaacg tgctcagcgt ccggcaaaat atagctacgt tgacgaaaac
     1801 ggcgaaacta aaacctggac tggccagggc cgtactccag ctgtaatcaa aaaagcaatg
     1861 gatgagcaag gtaaatccct cgacgatttc ctgatcaagc aataatcttt tgtagattgc
     1921 acttgcttaa aaatcccgcc atcggcggga ttttttattg tccggtttaa gacaatttaa
     1981 taagaataag ctataaaaaa acggcgtcga ttgctcaacg ccgtttcgtg gataacaccg
     2041 atacggatgt tacttcttaa tgcccatctc ttcttcaagc caggctttaa attccgtgcc
     2101 aagggtgtta tgacgaatac cgtattcaac gaaggcctgc atgtaaccta atttattacc
     2161 gcagtcatgg ctcttccctt tcatatgata ggcttccacc gtttcttttt cgatcagcat
     2221 atcaattgcg tcggtgagct gaatttcatc accagctccc ggaggggttt ttgccagcaa
     2281 cggccaaata tccgcgctaa gtacgtaacg ccccacaata gcgagattag acggcgcaac
     2341 atccgctttt ggtttttcaa ccacgccaac catcggtacg ctttcacccg gtgctaattc
     2401 aacgcctttg caatccacaa cgccatatgc ggtcacatca gcaaccggtt caaccatgat
     2461 ctggctatga cccgtttcat caaagcgtcg gatcatctct gccaggttat cctgtgacaa
     2521 atcggattca tattcatcca gaataacgtc aggcaaaata acagccacag gttcatcacc
     2581 cactaccggg tgagcacaca ataccgcgtg tcccaggcct ttcgccagcc cctgacgaac
     2641 ttgcataata gtcacgtgcg gcggacaaat agactgcact tcatcaagca gttgacgttt
     2701 tacacgtttt tccagcattg cttccagttc aaaactggta tcaaagtggt tttcaataga
     2761 gtttttagat gagtgagtaa ccagcacaat ttcagtaatg ccagccgcaa tacattcatt
     2821 cacgacgtat tgaattaatg gcttatcgac aagtggcagc atctctttcg ggatggcttt
     2881 cgtcgccggc aacatcctgg ttcctaatcc cgcaacgggg ataacggctt ttttgacttt
     2941 cgtattaatg gcagccattt aaattctcct ggactgttcg tgttttgaac gtgttcatat
     3001 ttctgtatcg catcccagta tatcagcacc ccgaaggggc taagttctga aaaggaggcg
     3061 agttagcata attaagacaa ttacttatac gaatggcgac gatagtacca ccagccgaca
     3121 ttagcaggta atgcaaattt agcccgcgtt atcgtttgct cattctgcag acaacatcaa
     3181 gcgaagccga ccaccggttc cccatatttg acattgccag gcatcgcatc gctggctcaa
     3241 ttgattcaaa taagcgttac ctaaagtgcc taacggaaca ccattactga tttgtacctg
     3301 gtgttcgccg gtatttaacg tcgcattcag acccgcagaa accagaatga gatttttcag
     3361 ttcgcgatga taatagccaa ctaatagcgg aaactgcccc ggcagattgg cctgacggag
     3421 taaatggttt acctgcttca ataacgcgcc caactctggc aaccgttgat tttggtgtgc
     3481 aagctgttcc tgtaataatc cgttaaacaa tgcgcgtaat aacaaggcag caagtacgcc
     3541 attatgtcca gctcgggtga catcaaggca ataaaatgcc agatcgtttt ccgaaagtgc
     3601 ggcaatatca agcaccaggc cgggtttgtc cgcggcaacc aattgacgat aattaacccg
     3661 gcaatgggaa atcacctgct gaaccggcgg ttgcaattcc tgtaataatt tcgccgctgc
     3721 ggcagggtta tcaaccattg catcccagtc gcgaaaaagc ctttcctctt cctcaacgcg
     3781 ggaattaaac atgctgggat agagacaggc aaaaaccatc tcgcgcaagc gattcagatc
     3841 tttaactggt ttcagcaaaa catcttcaac gcccagacgt aacgctttgg caatatctgc
     3901 catattttca gtggcagata tcaccagaac cggtgtctgg tcacctctgt tgcgtatatg
     3961 ttccagcagt ttaagcccgt tcattctggg catcgcgata tcacatatca tcaggtctgg
     4021 agtgaaacct cccagcaact caagggcatc caccccatca gccgccagta ccgttgtcgc
     4081 tcccaatgag gaaaaccacg aatccagaag cgagcgaaat acctgctcat cttcaacaat
     4141 gagaatctgt tttccgacca atggctgcgt catgttctct cccctgactg gctttactca
     4201 atagtggcat gctattgcca cctgcgcctg tcagaattaa cttaagtgta gataaaaatt
     4261 ctggtcaaat gttggtgcgt accaacggca aaagttcgtc cattttcttt tccactgcca
     4321 gctgcccagc cgcaatggca gcgtgcgcgc gatggaaatc aagcgtagat atttgcgggc
     4381 aaacaggttg aatcagaata tcgggcggat cacctgccat gcggttcctt ttaaggcggt
     4441 tctccagcac ctggatagaa gtggtcataa tctctgttgc cgttggcgct gtcaccgccc
     4501 gacgtgtcgt tatgctgccc aacctttctt tcagacgcgc atgccacggc agagaatcac
     4561 cattctcgct attttcttca ctgacattaa aggagagcag atcttgttgc atcaaatgag
     4621 catcgtgctg caggtcgacc gctatcacaa tatcagcacc caatgcacgc gtgagcgaaa
     4681 taggaattgg gttaactact gccccatcaa ccagccagta gccgttatgc gcaacgggtg
     4741 ccattagtcc tggaatactg catgatgcac gaatagcaag atggagatcg ccttcagtaa
     4801 accataattc gcgcccagta cttaaattgg tggcaacagc cgcgaagcga cgggaacaat
     4861 tttcgatctc tgtttccggc attatttcgc gatattgatt gaagacacgc tcgccgcgca
     4921 gtaacccacc gcgctgccag gagagatcca tcaggcgtaa aacatcccaa taactgaaag
     4981 aggttaccca atcttccagc gcagataatc gatcgcatgc ataggccgcg cccaccagcg
     5041 aaccaattga gcatcctgca acgatatcaa tttcaatacc cacttttttt agcgcattaa
     5101 taacgccaat atgcgaccaa cctctcgccg cgccagatcc cagcgccagc cctattttta
     5161 tctttctcat tattcccgca agattcccct ggaatgcaat cgtagccaca tcgctactgc
     5221 tcggttaaca tagtgctact caggcggtta atacgccgtt attgtttcca gggagattat
     5281 ttgtgtctca gctttgtccc tgtggtagtg ctgtcgagta tagcctatgt tgccaccctt
     5341 atgtgtctgg tgaaaaggtt gcacctgatc cagaacatct catgcgttcg cgttactgcg
     5401 cttttgtgat gaaagacgca gattatttaa taaagacctg gcatccatct tgtggagcgg
     5461 cggcgttacg tgccgaattg atggccggat ttgcgcatac tgaatggttg ggattgaccg
     5521 tatttgaaca ttgttggcag gacgccgaca atatcggatt tgtcagtttt gttgctcgat
     5581 ttaccgaagg tggcaaaaca ggtgcaatca ttgaacgttc gcgatttttg aaagaaaacg
     5641 gtcaatggta ctatattgac ggtacacgtc cgcagtttgg ccgcaacgat ccctgccctt
     5701 gtggttcagg taaaaaattt aaaaagtgct gcggccaata atggttgacg gtacggttta
     5761 gcaaacactc tcaacaaggt ttttccagca atgcattcac tccaacgtaa agttctgcgt
     5821 actatttgtc cggaccaaaa aggtctgatc gcacgtatta ccaatatttg ctacaagcac
     5881 gagttaaata tcgtgcagaa caatgaattt gttgatcacc gtaccgggcg cttttttatg
     5941 cgcacggaac tggaaggaat ttttaatgat tccaccctgc tggcggatct cgacagcgca
     6001 ttgccagaag gctccgtacg tgagctgaat cctgccggtc gtcgccggat agtgattctg
     6061 gtcactaaag aggcgcattg ccttggcgat ttgttgatga aagccaatta cggcggcctg
     6121 gatgtcgaaa tcgcggcagt tattggtaac cacgatactt tacgttctct ggttgagcgt
     6181 tttgatattc cgtttgagct ggtaagtcat gaaggattaa gtcgcaacga gcacgatcaa
     6241 aagatggcgg atgccattga tgcttatcag cctgactacg tggtgctggc gaagtatatg
     6301 cgggtattaa cgccagaatt tgtggcacgc ttcccgaata agatcatcaa tattcaccat
     6361 tcattcctgc cagcgtttat cggcgcacgt ccttatcacc aggcctatga acgtggcgtg
     6421 aagattattg gcgcaaccgc tcactatgtg aatgacaatc tggacgaagg tccaatcatc
     6481 atgcaggacg ttattcatgt cgatcatacc tacacagctg aagatatgat gcgcgcaggt
     6541 cgtgacgtcg agaaaaacgt cttaagtcgc gcactctaca aagtactggc gcagcgcgtc
     6601 tttgtttacg gtaatcggac gattattctt taatcgccag caaaaataac tggttacctt
     6661 taatccgtta cggatgaaaa ttacgcaacc agttcatttt tctcaacgta acactttaca
     6721 gcggcgcgtc atttgatatg atgcgccccg cttcccgata agggagcagg ccagtaaaaa
     6781 gcattacccc gtggtggggt tcccgagcgg ccaaagggag cagactgtaa atctgccgtc
     6841 atcgacttcg aaggttcgaa tccttccccc accaccaata cttcctgaaa tactcaaaac
     6901 ctgttactcc gagctaattc tgcccgatgg caccgcgttt accggaccta aaatatcctc
     6961 ccctgaagtt cggataagcg aagcgcatcc gacaactcac cccgcaccgt gcccataaaa
     7021 aaaccccgcc gaagcagggt ctatgtgaac taaaattcgc ttagtgacga gcgcgcacca
     7081 gctgatactt acgtgtcaga tactccaccg ggacgctcca gatgtgcacc agacgcgaga
     7141 acgggaacag caggaataac gtcatcccca gcaccaggtg cagacggaag ataaacgcca
     7201 caccatcaag gtgttgagaa gcgccaccgt ggaaggtcac taccgactgc gcccagccaa
     7261 ccagtttcat catctcgcta ccgtccatat gttgggcgga gaacggaatg gtcagcaagc
     7321 ccagcgcgca ctggataacg agcagcgaca ggatcaggat atccgctccg gtagtggttg
     7381 cacgcacgcg tgggctgaac agacgacgct tcagcaacag cacgccgcca atcagacaca
     7441 gcacaccgct ggcaccacca gcaaacatcg ccattttctg tttcacttca atcggcagcc
     7501 aggcttcata catccagtgc ggcgtcaaca taccgaagaa gtgaccgaca aaaatcccca
     7561 gaataccgat atggaacagg ttcgatgcca ggttcatccc tttgcgatcc agcatctggc
     7621 tggacgccgc gcgccaggtg tactgcccgt agtcataacg cagccagcta ccaatcagga
     7681 agaccgcccc ggctatgtac gggtagatat caaagaagaa catattcagg aattgcatta
     7741 gtgctgtcct ccggtggtga tattcagata ttgcggtgcg acggcaccgg caaagcgacg
     7801 ttgatgggca gtgattgctg aatcaccgca gcctttgtca gcaaagaatt taacctgctc
     7861 ttcttcccaa acggcatcca gcgcctgcgg cgtatcgtcg cgcgcttcgt cggcaatttt
     7921 ttccgccact ttgtcgctgt cgatagcggt attcgccagt ttcagcagca gatcaaacag
     7981 cacggcataa cggctttcac gctgttgcag acgcgcactc agcaatgcca gaatcggcgc
     8041 aatatctttc aaaccttcca cggcttcgct ttgcggcagc tgcgccaggt actccagata
     8101 cagcggcaga tggtcgggca attcgcggct gtttaactgc aaaccgtgct gctcatactg
     8161 cgccagcagg tctaccatcg cctgaccgcg gtcgcgggat tcgccgtgca catgttcaaa
     8221 cagcaacagt gacgtggcgc ggccacggtc gaacagttcg ctgtactggg cctgagcatc
     8281 gagcggatcc atcgccgtta aatcgcgcag gaaaatgccc agcgcatggg catcttcttt
     8341 cgacagattt ttcgacgcgg caatcgcctc aaacatctct tgttgatgct gccataaggc
     8401 agcatccgga tattcaagga gacgcgatac aatcacgagt tcgatcatgg gtgcggctcc
     8461 gttttgctgg ttacgtcgat ggcatcgata cggcggctgt tgaacagatt gaatttggta
     8521 tctgaaccgt ggcagccatc accaaaggta aagccgcagc catttttctc cgggaaggct
     8581 tcccgcgcca gttcacgatg actactcggc accacaaagc gatcttcgta gttagcaatc
     8641 gccagataac ggtacatctc ctgtgcctgg gcttcggtca gaccgacctc ttccagcgca
     8701 cgggtatcca ctttcccgtc aacggtttca gcacgtttat aatgacgcat cgccagcata
     8761 cgtttcagcg cgcgcagtac cggtttggta tcaccggcgg tcagcagatt cgccagatac
     8821 tgcaccggaa tgcgcaggct ttcgacgtct ggcagaatgc cgttgctacc cagctcaccc
     8881 gcgtctgctg cagactgaat cggagacaga ggcggcacgt accagaccat cggcagtgtg
     8941 cgatattctg gatgcagcgg cagcgccagt ttccattcca ttgccatttt ataaaccggc
     9001 gactgctgtg cggcttcaat aacgctcagc ggaataccgt ctttaatcgc ctgctcgatg
     9061 actttcggat cgttcggatc gaggaacacg tccagctgac gctggtaaag atctttctcg
     9121 ttctcagtgc tggctgcacg ttcaatagcg tcggcatcgt acaacagcac gccgagataa
     9181 cggatacgac cgacacaggt ttctgagcac acggtcggct gacccgcttc aatacgcgga
     9241 tagcagaaga tgcacttctc agacttaccg ctcttccagt tgaaatagat ttttttgtac
     9301 gggcatccgg tgatgcacat acgccagcca cggcatttat cctggtcgat caggacgatg
     9361 ccatcttctt cacgcttgta aatcgcaccg ctcgggcagg tcgccacaca tgccgggttc
     9421 aggcagtgtt cgcacaggcg cggcaaatac atcatgaagg tgttttcgaa ctggctatac
     9481 atcgccttct ggatgttgtc gaagttcttg tctttcgcca gcttgtcgaa ctcaccgccc
     9541 aggtcatctt cccagttcgg ccctttttcg attttcgcca tccgttcgcc ggtaatcagc
     9601 gaacgcggac gggcaatcgg ctgcgacttg ctgccttccg gcgcggtatg caggttctga
     9661 tagtcaaaat cgaacggctc gtaataatcg tcgatccccg gcagatgagg gttagcgaag
     9721 attttaccca gcagcatggc tcggttaccc atgcgcggtt gcagtttgcc attgatttta
     9781 cggatccagc cgcctttgta tttttcctgg ttttcccagt cagtcgggaa gccctggccc
     9841 ggcttggttt ccacgttgtt gaaccacgcg tattccacgc cttcgcggct ggtccagacg
     9901 tttttacagg taactgaaca ggtgtggcag ccgatgcact tatcgagatt cagcaccatg
     9961 ccgacttgtg aacgaatttt cattttacgc tctcctgtac ctggtcattg ccttcgccat
    10021 ctaaccagtc aatgttcttc atcttacgca ctacaacaaa ctcatcgcgg ttagaaccta
    10081 cggtgccgta gtagttaaag ccgtatgcca gatgggcata gccgccgatc atatgcgtcg
    10141 gtttcggcgt gatacgggtg accgagttat ggataccacc acgctgttgg gtaatttccg
    10201 aaccaggcag gttaacgata cgttcctgcg cgtggtacat catggtcatc cctgccggaa
    10261 cacgctggct gacaaccgca cgggcagtca gagcaccgtt gctgttgaag acttcaatcc
    10321 agtcgttatc ggcaatgccc agatctttgg catcggcttc actcagccag accactggac
    10381 caccgcgacc taaagtcagc atcagcaggt tgtcgctgta ggtggagtgg ataccccact
    10441 tctggtgcgg cgtcaggaag ttgagcgctt tttccgggtt gccgttggat ttctgcccca
    10501 tcacttcttt caccgaacgg gtgtcgatcg gcggacgata aaccagcagg ctttcaccga
    10561 aatcacgcat ccactggtga tcctgataca gttgctgacg accagagagc gtacgccacg
    10621 ggatcagctc gtgaacgttg gtgtaaccgg cgttgtaaga aacgtgttca tcttccagac
    10681 cagaccaggt cgggctggag ataattttgc gcggctgtgc ctgaatatcg cggaagcgga
    10741 tcttctcgtc ttctttattc agcgccagat gcgtatggtc acgaccggta aactcgctca
    10801 gggcagccca ggcttttaca gctacctgac cattggtttc cggtgccagc gtcaggatca
    10861 tctctgctgc atcaattgcg gtattgagca tcggctgacc ttttgccgga ccttccgctt
    10921 tggtgtagtt gagcttacgc agcagatcca tctcgctctg ggtgttccag gcaatccctt
    10981 taccgccatt accgattttc tccatcagcg ggccgataga ggtaaagcgt tcgtaagtcg
    11041 ccggataatc gcgctctacg accataatgt gcggtgcagt tttacctggg atcaggtcgc
    11101 attcgccttt tttccagtct ttcacatcca gcggctgcgc cagttcagcg gcagagtcgt
    11161 gctggatagg cagcgtgacg atgtcggttt ctttacccag atggccgacg cacacttcgg
    11221 agaatttctt cgcgatggct ttgtagattt cccaatcgct tttcgcttcc caggccggat
    11281 cgaccgccgc agacagcggg tgaataaacg gatgcatatc cgaagtattc atgtcgtctt
    11341 tttcgtacca ggtcgccgtc ggcaaaatga tgtcggaata gagacaggtg ctcgacagac
    11401 ggaagtccag cgtcaccacc agatccagct tgccttccag accgttgtcc tgccagtcca
    11461 cttcttccgg cttcacgccg ccctgctgcc ccagatcttt gccctggata ccgtgctccg
    11521 tccccagcag gtacttgagc ataaactcat gacctttacc ggaagaaccg agcaggttag
    11581 aacgccagat gaacagatta cgcgggtggt ttttaccgtt ttccggctgt tccgcagcga
    11641 aacggataga accctctttc agggatttca ccgtatagtc caccggattc atcccggctt
    11701 tttccgcttc gccagcgata gtcagcgggt tagtgcctaa ctgcggtgca gacggcagcc
    11761 agcccatgcg ttccgcacgg acgttaaagt cgatcaggtg tccggtataa cgggatttat
    11821 ccgccatcgg tgacagcaac tcttccgccg tgacggtttc ataacgccac tggctggagt
    11881 ggttatagaa ataagaagtg ctgttcatgt gacgcgccgg acgctgccag tcaagggcaa
    11941 acgccagcgg ctgccagccg gtttgcggac gcagtttttc ctgacctaca tagtgcgccc
    12001 agccgccccc gctctgaccg acacagccgc agaaaatcag catgttgatc agaccacgat
    12061 agttcatatc gaggtgatac cagtggttca gccccgcacc gacgataatc atcgaacgac
    12121 cgtgcgtctt gtcagcgtta tcggcaaatt cacgggcaat acggataatc tggctacgag
    12181 aaacgccagt gatttgctcg gcccacgccg gagtgtaagc tttcacatcg tcatagctgg
    12241 ttgcacagtt aacgtcgttc aggccacgtt ccagaccgta gtttgccagt gtcagatcat
    12301 aaacggtggt caccagggcg gtgctgccat cagccagttg caggcgtttc accggtagct
    12361 tatgcagcag cacgttttcc agttccactt tgttgaagtg ttccgtgcca tcgccaccaa
    12421 agtacgggaa gcccacctca gcgatctcat cctggctacc cagcaggctc agttgcagct
    12481 cggtttcttc gccagttttg ccgtcgcgct gctcaagatt ccatttgccc ttctcgcccc
    12541 agcggaagcc aatagaaccg ttcggcacaa ccatttcacc attggtatta aaggcgacag
    12601 ttttccattc cggattgttt tcctggccca gtgcatccac cagatcagca gcgcgcagca
    12661 tacgacccgc agcgtagtaa ccgtcgcgct cttccagcat caccagcatc ggcatgtcgg
    12721 tgtagcggcg cacatagtcg gtgaaatact ggcttgggtt gtcgaggtgg aattcacgca
    12781 gcattacgtg acccattgcc agcgccattg ccgcatcggt gccctgtttc ggtgccagcc
    12841 acagatcgca cagtttggcg atttcagcgt agtctggtgt gacggcaaca gttttggtcc
    12901 ctttgtaacg cacttcagta aagaagtgag catccggggt acgcgtctgc ggcacatttg
    12961 aaccccaggc gatgatgtag ctggagttgt accagtcagc agattccggt acgtcagtct
    13021 gctcgcccca ggtttgcgga gatgcaggag gcaggtcgca gtaccagtcg tagaagctta
    13081 agcaagtacc gccaagcagc gagagatagc gcgcgccgga agcgtaagaa accatcgaca
    13141 ttgccggaat tggcgagaag ccagcgacgc ggtccgggcc gtagtttttg atggtgtaaa
    13201 cgttagaggc ggcgatcagt tcattcactt cctgccagga agaacgaaca aaaccaccgc
    13261 gtccacgcgc ctgcttaaag cttttcgctt tatcggcgtc ttcaatgata gaagcccatg
    13321 cctcaaccgg atcgctatgc agcgccttcg cttcacgcca cattttcatc aggcgtttgc
    13381 gcatcatcgg gtatttcagg cggttggcac tgtaaagata ccaggagtag ctggcaccgc
    13441 gcgggcagcc gcgaggttca tggtttggca ggtccgggcg agtacgcgga tagtcagtct
    13501 gctgggtttc ccaggtcacc agaccgtttt tgacgtagat tttccagctg caggagccgg
    13561 tgcagtttac cccgtgggta gagcggacga ttttgtcatg ctgccaacgc tggcgatatc
    13621 catcctccca gtcacggttg gtattgagaa gctggccatg cccatcggca aaggtttcac
    13681 ccttctgttt gaagtagcga aaccggtcca ggaatttact catcggtttt ctcctgtggg
    13741 agcctgtcgg ccctctgata aatcgacatt gctaatgttt aagggcaagg taacgctctg
    13801 aaacagcgtg agaattgata acgatcaaga gtgatgggga tgaaaaataa agtaaattcc
    13861 taagataccc ctttaggata attagcagtt acagcataac acgctgtaaa ttaagatgtt
    13921 ttatacctgt agttatttaa actattaaga tttttatgca gatgggtatt aaggagtatt
    13981 ccccatgggt aacatattaa tggctcttaa tgaaatccgg cgaaataagc catataatat
    14041 gagtatgttg taactaaatg acgaataaaa aaagcgcgac atcatgccgc gcaaaggata
    14101 atcaaatatt aagatttatt ttttagaatg ccgaccatat accgcccagg taatcaccac
    14161 gcaggcgata tagaaaatca aaaatacttt cattgcgccg actggcgaac ccgttaatgc
    14221 cagcgagcta ccaaacgctt tcgggataaa gaagccacca atcgcgccaa tcgcagagat
    14281 gaaacccagc gccgccgccg tgtcggttgc cgcttcacgc atcgcacgtt cgtcagaacc
    14341 cccttctgct ttcacgcgat ccattgtcag tttacggaag atcacggaaa tcatctggaa
    14401 agtggaacca ctacccagcc cagctgtcag gaacagcgcc aggaagactg cgaagaacgc
    14461 catgaagctt ccgccctgtc cgtcagtcgg taaggtcagg aacagcaggc cgctgaaaat
    14521 cgccatcagg ataaagttca ccagcgtgac acgagttccg cccagacggt cagataatgc
    14581 accacctgca gaacgcgcca gcgcaccaat aaacggcccg aagaaagcgt attgcagaat
    14641 ctgaacatcc gggaactgcg tttttgacag catcgcaaag cccgcggaga agccgatgaa
    14701 ggagccgaag gttgccagat acagcatgct cataatccac agatgacccc gtttgagtac
    14761 cggcaactgc tccttgatgg aggctttcga ggtagcaaga tcgttcatgc caaaccacgc
    14821 cgcaatggtg aagatggcaa ggaacggcac ccatacccag gacgcattcg ccagatacag
    14881 ctcagtccca tccggctgtt tgacaccctg gctaccaaat actgcgaaaa tcgacagtga
    14941 taccaccagc ggagcaacca actgcatgac gctgacgccc atgttgccca gaccaccatt
    15001 cagacccagc gcgccaccct gcttctgttt cggaaagaag aagctgatgt ttgccatact
    15061 ggatgcgaag ttcgcgccag caaagccgca cagcagagag atgatgatga agacgctata
    15121 aggcgtggcg gtatcctgca cggcaaaacc cagccagacg caaggaataa tcagaatacc
    15181 ggtgctgaac gccgtccagc gacgaccacc gaagatagga accataaagg agtatggaac
    15241 acgtaataac gcgccagaaa ccgaaggcag cgcagtcaac ataaatagct gatcggtcgt
    15301 aaaattaaaa ccgactttcg gtaagttcac cgcaacagcg ctgaacaaca tccatacgca
    15361 aaacgccagc agcagacagg gaacggaaat ccacaggttg cggctggcaa tacgttgacc
    15421 gcgttgctgc cagaacgcag gatcttccgg tcgccaatct gtaatgacag ctccagtagc
    15481 cctttcgggg gcggatgagt gactcataga cacctctgat actcgtttcg atgtctgcca
    15541 ccttagtgtc tgtagctaaa ggcaatttga tgtaaatcaa acgataagat aactttatct
    15601 atcattgata tttatcatta cccatagtga gtacagtgat ttcataaaaa ttatgagatt
    15661 tttcacggtg ctgtaaaatc cctaccctta ccgatgtaaa gcgactaacc acgcggcaaa
    15721 taaggagtaa ctctttccgg gtatgggtat acttcagcca atagccgaga atactgccat
    15781 tccagaatgt atcgtcacat tcattaaggt tattgctcat ttaaagcctg aaggaagagg
    15841 tttacatgct taaacgttgt ctctctccgc tcaccctggt taatcaggtt gcgcttattg
    15901 tgttgctttc tactgctatt ggactggcag ggatggcagt ttctggctgg ctagtgcaag
    15961 gcgttcaggg cagcgcccat gcgatcaaca aagcgggatc actgcgcatg caaagttacc
    16021 gtctgttggc ggcagtgcca ttaagcgaga aagacaagcc cttaattaaa gaaatggaac
    16081 aaacggcatt tagcgccgag ttgactcgag cagcggaacg agacggacaa ctggcgcaat
    16141 tacagggttt acaagattac tggcgtaatg aactgatccc tgcgctgatg cgtgcacaaa
    16201 accgcgaaac ggtgtcagcg gatgtcagcc agtttgttgc cgggcttgat cagctggtat
    16261 ctggttttga ccgcaccacg gaaatgcgca ttgagacagt ggtactggtc catcgggtaa
    16321 tggcggtatt tatggcactt ttactggtgt tcactattat ctggttgcgg gcgcgactgc
    16381 tacaaccgtg gcggcaactg ctggcaatgg cgagtgccgt cagccatcgc gattttaccc
    16441 aacgcgcaaa catcagcggg cgcaacgaaa tggcgatgct tggaactgca ttgaacaata
    16501 tgtctgcaga actggccgaa agttatgccg tacttgagca gcgggttcag gagaaaactg
    16561 ccgggctgga gcataaaaat cagatcctct cttttttatg gcaggctaac cgccgtttgc
    16621 attcccgcgc cccgctgtgt gaacgcctgt caccggtact caacggctta cagaatttaa
    16681 ccctgctacg tgatatcgaa ctgcgggttt atgatactga tgatgaagag aatcatcagg
    16741 agtttacctg ccagccagat atgacttgtg atgataaagg ctgccagctc tgcccgcgcg
    16801 gcgtattacc cgttggcgat cgcggtacaa ccctgaagtg gcggctggct gactctcata
    16861 cgcagtacgg tattttgctg gcgaccctgc cgcaggggcg tcatcttagc catgatcaac
    16921 aacaactggt ggataccctg gttgaacaac tcaccgccac gctggcgctg gatcggcatc
    16981 aggaacgtca gcaacagttg atcgtgatgg aagagcgtgc caccattgcg cgcgaactgc
    17041 atgattctat tgcccaatct ctctcttgca tgaagatgca ggtgagttgt ttacagatgc
    17101 agggcgatgc gctgccagaa agcagccgcg aactgttaag tcagatccgt aacgaactga
    17161 atgcatcctg ggcgcagttg cgtgaattgc tcaccacatt ccgcttgcag ctcaccgagc
    17221 ctggattacg tccggcgctg gaggcgagtt gcgaagagta cagcgccaaa tttggcttcc
    17281 cggtgaagct ggattatcaa ttgccgcctc gtctggtgcc ttcgcatcag gcaatccact
    17341 tgttgcaaat tgcccgtgag gcattaagta acgccctcaa acattcgcaa gcgagtgagg
    17401 tcgtggtgac ggtggcgcaa aacgataatc aggtcaaact gaccgtccag gataacggct
    17461 gcggcgtgcc tgaaaatgcc atccgcagca atcactacgg catgataata atgcgcgacc
    17521 gtgcgcaaag tttacgaggc gattgccgcg tccgccgtcg tgaatcaggt ggcaccgaag
    17581 tggttgtcac ctttattccc gaaaaaactt tcacagacgt ccaaggagat acccatgagt
    17641 aatcaggaac cggctactat cctgctgatc gacgatcacc cgatgctgcg aactggcgta
    17701 aaacagctta tcagtatggc accagatatc accgtggttg gcgaagcgag taatggcgaa
    17761 cagggtattg aactggcgga atctcttgat cccgatctga tcctgttaga tctcaatatg
    17821 cccggcatga atggtctgga aacgctggat aaactccgcg aaaagtccct ctcagggcgc
    17881 attgtggtat tcagcgtctc taaccatgaa gaagatgtgg tcaccgcact gaaacgcggc
    17941 gcggatggct atctgttaaa agatatggaa ccggaagatc tgctgaaagc gttacatcag
    18001 gcagctgctg gcgaaatggt attaagcgaa gcattaacgc ctgttctggc cgccagcttg
    18061 cgcgcaaacc gtgccactac tgagcgcgac gttaaccagt taaccccacg cgagcgcgat
    18121 attctcaagc tgattgccca gggtttgccg aacaagatga ttgcccgccg cctggatatc
    18181 accgaaagca cagtaaaagt gcacgtcaag cacatgctga agaaaatgaa gctcaagtct
    18241 cgcgtggaag cagcggtatg ggtgcatcag gagcgcattt tctgattacg gttcccagcg
    18301 cagttcgtcg tttgacaatg catcgaacgg ttcgacaagc gttagcgtga tctcattgga
    18361 ggagacacgc tgcccctggt tatcttccac caccaccgac aatcgccagt gattgctcgc
    18421 cccttccccg ttctgccagt caggcatgat cagcgtccag ccctccacgc tgttggcttg
    18481 tgcgcccggc gtcaaactta atatctgcgt atcgccctgc caaatcagtt gccgaatacc
    18541 gtaacgactg cggatttgta atttcagcgg cactgtttcg ccaggtttta gatcccacgg
    18601 cggtgtcgcc agaaacaccg ttagggtttt tcgctgtcgg tactcaagag tcggaagatt
    18661 atttcgctgc ggattgtcat agcgactacc acgtaacgac tgactttcgg caacttcgcc
    18721 cgcagaaagt tgttttttga gcggtacacc aaagcggtag ttaagattca gcccgaggtt
    18781 attttgattc tcgccacttt caccctgttt atgctgggcc gtcacagtga ctaagggcac
    18841 aggggtgtaa tttaatccca gactcaacgc gacgggattg tgataacccg taccagagtt
    18901 aaacaaatca acacgatcac caaaatactg ttctacgctg acactggtat tgaggtgttg
    18961 atagaacggc atgcgcatcc gggctgtcag gtcgtacccg cgcgccatcc gttgttcctg
    19021 cgtggctgtc tgttcatgcc atgcagcaaa cggctgataa aagtttgccg atagtcgcaa
    19081 atattcgccc cacgcttcgg caccaaagcc cgctcgctga agattttcgt ccagcaagtt
    19141 gtcataaaaa gtgttataac ccaccagcca gttgccgcgc gcccagcgtt gccctacgcc
    19201 cacattgctc accaagccat catcctgctg agtaagacca agctggctcc aggtgagata
    19261 acgatcatta tcttgtaacg gcacaaacca gcttccacga ctgccggtga aatgtccttc
    19321 gttatccact ttgacgtcaa cactggcatt tccccacggt gatagccacg actcaacgtg
    19381 ctgattaacc tgttgactaa gcgcgtcgcg gacttttccc aatgcgaaag cttttgcctg
    19441 ctcgccagta tccagcccgt tatcattcat actggtttcg ccgaaatctt tcacaatttc
    19501 agcaaagtgt ttttccccat catgattttc gggtgccatg cctaaatccg gcagaccatc
    19561 attgttatta tcaaagggat ttgccgcttt ttgctcgaag gtagattgtg cgttagctgt
    19621 accgcctgcc gccagcaaga gtaaataaaa cggaataatg cgaggaacga aacggctcaa
    19681 aacgtcggta acttccggta aaaatgaaaa accatagcct taaagaataa cgattactgg
    19741 caccttttgt cgtattttct cgcgctttca ggaaaatcct taaaaatgtg accgattggt
    19801 cagacgctgc agaagcggta agatagaaga tgagtgtcta attccctgaa tacaggagta
    19861 aataatgcaa aaaatcgtga tcgttgccaa tggcgcacct tacgggagcg aatccttgtt
    19921 taacagcttg cggctggcca ttgcgttacg agagcaggag aacaatctgg atctgcgtct
    19981 gttcctgatg tctgatgcgg tcacagccgg gttgcgcggg caaaaaccag gggaaggcta
    20041 caacattcag caaatgctgg agatccttac cgctcagaat gtaccggtga aattgtgcaa
    20101 aacctgtact gacggacgcg ggattagcac acttcctctg attgatgggg tggaaatcgg
    20161 tactcttgtg gaactggcgc aatggacgct gtcagccgat aaagtgctca cattttaatg
    20221 tttgaggggg cgtctgacgc cccactatga gggaagttta ctcaggcgaa tcccggccgt
    20281 aacacagcat ccggataatt ctccgccagc agttttttta ccgataccag caaatcattc
    20341 agcccatcgt cctgcattcc cagtttgata agctcctgtt ccagtgaaaa caggtattgt
    20401 gcattggttc ccagcggacc gctcgccgcc gcaatcaacg gcgcgatgac ctgagcgcga
    20461 gtgtcagatt catattctgg atgtcgcggg tccataataa acacaatggc gtttactgtg
    20521 cgtccatcat caagatcaag ctgacaccag gttggcagat aacagccggt aatcatctcg
    20581 cgcttccaca acagggttag ttcctgctcc agcgtctctt ctggcagtcg ataggcgacg
    20641 cctgtggtgc gtccgccctc tttcagtgca agcatccgtc ccggctggtg cgcagtcccg
    20701 cgcccggcgg tcaggcgcag gcaaaacgcg cgatgccatc caaccagtgt accggtgcac
    20761 gactcggtaa actccagtgc cggattccac atcaacgatc cataaccgaa gatccacacc
    20821 ggtccctcat caggtcgaca agccagcgtc gccgccagcg aagccgcccg ttgctctgct
    20881 gaccataaga gtgattcttc aatggcacca aatgccgttt tacaatcggc attcatcaag
    20941 aaatcacgcg ttatcacctt acacctccgc cactgcatac ttccctgcga caactttttg
    21001 gtgtcttccg gacattttta ctgctcattt tgaaaccact aacgggacaa tatgcaatcc
    21061 acggaccact tgcaaggcaa caccgcacga atagctttaa ctaagctacc ggttttacga
    21121 ttttttatgc catttatcat catccccttt ggcatattca tgcttcacag cagcccaggc
    21181 cactttatgc gcggtttctt cgcgactggc gtcatcacgc cgatcttctt tatctttata
    21241 ttgatcccat gcgctgttga acgcttcttt atagatatcc tgagcatgag acggaagcac
    21301 gtgctttacg ctttccggca gatcgctttt cgttttatac ggcatcgttg actcctttta
    21361 caaagttgaa cattaagtgt ggtcaacaac atctactctt gccaaaacat aagaattttc
    21421 atgtcagact cttcttaaga agtgctaaaa caaacattgt ctaaacgcat tgcttatttt
    21481 tatggcccga tgagtaaaaa atcgacagcg gggtaaaaat tcgtaaaatg ttaccgatat
    21541 ccagacactt tctgttattt ttcctaccta ttttttacat tttcgataaa ttcatctgca
    21601 aagggataac cataatgtca aatgctcaag aggcggtaaa aacccgccac aaggagactt
    21661 cgcttatttt cccggttctg gcgctggtag tgctgttcct gtggggaagc agccagacac
    21721 taccagtggt cattgccatc aatcttcttg ctcttattgg tattttaagt agcgccttta
    21781 gtgttgtccg tcatgcggac gtattagccc atcgcctggg agaaccttac ggttcgctta
    21841 ttcttagcct ttcagtggtt attcttgaag tcagtttgat ttcagcttta atggcaaccg
    21901 gcgacgccgc gccaacgcta atgcgtgata cgctctattc aatcattatg attgttaccg
    21961 gtgggctggt tggcttttca ttattgttgg gcggacgcaa gtttgccacc caatatatga
    22021 atctgtttgg tatcaagcag tatttaattg cgctgttccc cctggcgata atcgtactgg
    22081 tatttccaat ggctctgcct gcggcgaatt tttcaaccgg tcaggcgtta ctggtagcat
    22141 taatttctgc ggcaatgtat ggcgtatttt tgctgatcca gaccaaaacg catcaaagtt
    22201 tgtttgtcta cgagcacgaa gatgacagtg atgatgacga cccgcaccac ggtaaaccgt
    22261 ctgcccatag cagcctgtgg catgctatct ggttgattat ccatctgatt gccgttattg
    22321 cagtcaccaa aatgaacgcc agcccgctgg agacattgct cgacagcatg aatgcgcctg
    22381 tcgcctttac tggcttcctg gtggctctgt tgattctgtc gccggaaggt ttaggtgcgt
    22441 taaaagcagt gttgaataac caggtccagc gcgcgatgaa tctgttcttt ggttcagtgt
    22501 tagcaaccat ttcgcttacc gtacctgtcg tcacgctaat tgcctttatg acgggtaacg
    22561 aattgcagtt tgcacttggt gcgccagaaa tggtggtgat ggtggcctct ttagtactgt
    22621 gccatatctc cttctccacc ggacgaacta acgtgctcaa tggcgcagcg catctggcac
    22681 tgtttgccgc ctatttgatg acgatatttg cctgacagtt atatctcctc tgatgacaga
    22741 aatcggggga gataatataa attcctgctt attgtatttc ttcatactac ctgaacaggt
    22801 cgttaatcag aattgcgagc ctgtaccaca acctgcacga aaccactgca acagctgttg
    22861 aaaagccgga atgtactctt tattgcaaac atttcaggga tgaagtgaag atgaattgag
    22921 acgtaatatc cacaccaagc cggcgttatc cggtgaggcg caatgttgcg ggggctttat
    22981 ccctggtggc attggttgct ggaaagagaa aaccccgcac gttgagaggt aaaacctgac
    23041 aacagaacgg gggctaatct tgaaccatca acaattcaag aatagccgca aaatgttgtc
    23101 attacaacaa ggcggctata tgacgctcgc gcagtttgcc atgattttct ggcacgacct
    23161 ggcggcaccg atcctggcgg ggattattac cgcagtgatt gtcagctggt ggcgtaaccg
    23221 gaagtaaggt gaaaacgggc gtcaggctgc cgtgatggca atatgcgccc gaaaccggcc
    23281 gtaggggtaa cagcctgcgg ccctttttgt ctttatctct tctgcaagta aatattggca
    23341 acccgagctg gaagcatcat ccagagcact catgaaacga ctgtaacagc tgttgaaaaa
    23401 ccggaatgca ctcttcattg caaacatttc agggatgaag tgaagatgaa ttgagacgta
    23461 gtatccacac caagccggcg ttatccggtg aggcgcaatg ttgcgggggc tttatccctg
    23521 gtggcattgg ttgctggaaa gagaaccccc ccgcacgttg agaggtacaa cctgacaaca
    23581 gaacgggggc taatcttgaa ccagaacaat tcaagaatag ccgcaaaatg ttgtcattac
    23641 aacaaggcgg ctatatgacg ctcgcgcagt ttgccatgac tttctggcac gacctggcag
    23701 caccgatcct ggcgggaatt attaccgcag tgattgtcag ctggtggcgt aaccggaagt
    23761 aaggtgaaaa cgggcgtcag gctgccgtga tggcaatatg cgcccgaaaa cggccgcagg
    23821 ggtaacagcc tgcggccttt tttgtatccg gcacccatga aaaaaacctt aacgcagaac
    23881 gctaaggctt tagttttcag gcaaaaaaga ttacttgctg gtatccagtt cttcgaaacc
    23941 tttcaccagg tcatcaatcg ctttcatctg cttgaggaac ggttccagtt tagccagcgg
    24001 cagcgcggat ggaccatcac atttcgcatg ttccggatcc ggatgcgctt caataaacag
    24061 ccccgccaga cctaccgcca taccggcacg tgccagctca gccacctgag cacgacgacc
    24121 accagaagct gcaccaaacg gatcgcgaca ttgcagtgcg tgggtaacgt cgaaaatcac
    24181 cggcgaatta ccagacactt tcttcatgat gctgaagccc agcatatcaa caaccaggtt
    24241 gtcatagccg aagttagcac cgcgatcgca aagaatcact ttttcgttgc cgccttcttt
    24301 gaatttatca acgatattac ccatctgtcc cgggctgaca aactgcggtt tcttgacgtt
    24361 aattaccgca ccggttttcg ccatggcttc aaccaggtct gtctggcgag caagaaacgc
    24421 cggcaactga atcacatcca caacatcagc aacgggctga gcctggcttg gttcgtgaac
    24481 gtcggtgata attttcacgc caaaagtctg cttcaactcc tggaagattt tcatcccttc
    24541 ttccaggccc ggtccacgat aagagtggat ggaggagcgg ttggctttgt caaaagaggc
    24601 tttgaacacg taagggatac ccagtttctg ggtcacggtt acgtagtgct cgcaaatgcg
    24661 catcgccaga tcgcgagatt ccagcacgtt cataccacca aacagtacga acggcaggtc
    24721 atttgctacg ttgatgtcgc caatgctaac cactttttgt ttcataggat cgccttaatc
    24781 ttgagtaaaa tgtcgattaa ttaatgcagc acaatatgtt tatgcgcgat gttatttatt
    24841 tgcacacgga tcatttcgct gatcgggtct tccggacact gttcaacgaa ataacttaaa
    24901 tcgttcaacg caacgtgttc gcaatccagt tgcgcataaa tcaacccgcg atcgcgaatt
    24961 tcatagggat cttccgggtt aaattgtaat aaagcttcgc tggtacgtag cgccagctcc
    25021 atctgatttt cttccatcaa cgaggctttg agtgtatcca gcaatttgcg gattacctca
    25081 atgttatcag cttcatcaag gtcttcataa aacagttccg ccgacgggct gatatttccc
    25141 tttaaccata cgtccagcat atgttcgctt aacgattcac cgttaaaagg attaatcagc
    25201 caaatttcgc catccggaca ttcaaagcgc aatatcagct gcgtagggaa aatcaccggc
    25261 agcagtggca aatcgagacg attcgcgacc cataataaaa cggcacctaa tgataccgca
    25321 ctgccctgtc gattctttaa cacctggtcc agccataatg catcggaaag acgataaacg
    25381 ccgcgtgagg ctttaaatcc ccagtcgccg taaaacagcg cgatcagttt ttccagctgc
    25441 tcttctaaag gcagaagctg gctgatttct tccttcgcca gactaacgag acgctccagt
    25501 tcgtcgtaaa catcttgcga gggaaaatcg cggcggattg cttcgcaagc caggatcatg
    25561 ccttcgcaca atggcgcttt attaaattcg aaatcagcta acgatctcat gacttacccc
    25621 agtaacggta cttttgtggt ggcgagttta atgatgatgt acagcaccac caacgccagc
    25681 gggaaggcaa taatgcgcgc ctgctgactg tgcatacgac gataatcgag tgcaataaaa
    25741 cccaaaacga tataaatgat aactccaaac agcttttcag tcagccactg tgcctgcccg
    25801 gaaaatggca ggatgtgcgc tttagccatc aacgcaatgc cgcttaacaa taacagcgta
    25861 tcgacaaccg gcggcacaat gcgcgtccag cgcgcaaatg cctgtggatg cttctgataa
    25921 cgtagccaga aacgtaaggt taatagccca acagaaagcg cgatactaat aagatgaaca
    25981 ctaagcagtg tagaaaaact tgtcattgat aatagcggcc gagcgttacg cgctcgttat
    26041 caccatagtc ccgacaggtt tcgacgtcat gatatcccgc gtggataaat gcctgtcgca
    26101 ccgcttcgcc ctgctgccag ccatgttcca gaagcagaaa gccgccggat accagcgcgt
    26161 tacgcgactg ttcgatgata tgcacgatgt ctgccattcc actgtctgcc gcaaccagcg
    26221 cagtgagcgg ctcaaagcgg acatcgcctt gttgaagatg tgggtcctgc tcgtcaatat
    26281 acggcggatt actgacaatc atcgcaaact gctgcccggc tagcgcgcta aaccagtcgc
    26341 tttgcagaat atggatgttt ttgatcgcca gattctgagc attacgttgc gccagagaga
    26401 cagcatctgg catacgatct acagcggtaa tttcgcagtc cgggcgctcg ctagccagcg
    26461 ccagcgcaat cgccccggta cccgtcccga gatcgagaat acggcaaggt tgttcaggca
    26521 accgcgccag tgcctgctcc accagacact ccgtatccgg gcgcggaatt aaggtcgctg
    26581 gcgaaacaaa taacggcagc gaccagaatt ctcgcacccc ggttaaatga gcaataggtt
    26641 caccatcgcg acgacgcgtc agtagcgcat caagttgctg acattgttcg tcagtcagct
    26701 gcgtttcacc aaaggcgaga ataaaagtac gccctttgcc ggtaacatgc gccagcagga
    26761 tttcagcatc acgccgcggg ctttcgctcg cctgaagttg gcttattgct tcacgtaacc
    26821 agtgttgata ttccattatt cctgctcgga caacgccgcc agttggtcgg cctgatgttc
    26881 ctggataatc ggttcaatta gcatatccag cttaccttcc atcacttcat ccagacggta
    26941 gagcgtcagg ttgatgcggt gatcggtaac gcgcccctgc gggaagttgt aagtacggtt
    27001 acggtcgctg cgatcgccac tccccagcag gttacgacgg gtagacgctt cggcctgttg
    27061 ccgttttgcc atttctgcag cgtggatgcg agcaccaagt acagaaagtg ctttagcttt
    27121 gtttttatgt tgtgaacgtt cgtcctgaca ttcaacaaca atccctgtcg gcaagtgagt
    27181 aatacgaatt gccgaatcgg tggtgttaac gtgctgacca cccgcccctg acgagcggaa
    27241 agtatctatg cgcaaatctg ccgggttgat gtccggcagt tctgcgtcag gcagttctgg
    27301 cattaccgca acggtacaag cagaagtatg aatacgcccc tgcgattccg tagcaggcac
    27361 acgctgcacg cgatgaccgc cggattcaaa tttcagacga ccatacacac catcaccgct
    27421 aattttggcg atgatctctt tataaccacc atgttcaccc tcgctggcgc tcatgatttc
    27481 tacccgccag cggcgggctt cggcataacg gctgtacata cggaacagat cgcctgcgaa
    27541 cagcgccgct tcgtcgccgc cggttccggc acggacttcg aggaaggcgt tacgttcgtc
    27601 atcaggatct tttggtagta acagaacctg taattgctgt tccagttgct cgcttttttc
    27661 tttagcttcg cgcagttcat cctgcgccat ctcacgcatt tcaggatcat cgagcatcat
    27721 ctgtgcggtt tcgatatctt cctgaacctg ttgccagtcg gtaaaactgc gcgaaacatc
    27781 acttaactgc gcatattcgc gtgataatgc gcgaaaacgt tcctggtcgg cgatagtttg
    27841 cgcgtcaccc agcaacgcct gaacttcttc atggcgttca tgcagggctt ccagtttggc
    27901 aacgatagaa ggcttcatag gcgtaaatgc accctgtaaa aaaggaaaat gatgtactgc
    27961 tactccagcc cgaggctgtc gcgcagaata ttcaggcgtt cgttatcccc gtcacgggcg
    28021 gcctgttgaa gtgatttcgt tggcgcatgg atcaggcggt tagtcagttt ccatgccaga
    28081 tcctgcataa tggcttgggc gtcgccgccc tgctcaaggg ccgctaacgc tttggcggtt
    28141 aactcatcgc gaacgtgctc tgcctggctg cgatactcgc gaatggtctc gctggcgctt
    28201 tgtgcacgca accacgccat aaattcgctg gtttcctgag cgactatagt ttccgcctca
    28261 actgctgcgg ctttacgctg cgccagattg tgcgaaataa tgctttgcag atcgtcaacg
    28321 ctataaagat aagcattcgc cagtttacca acttccggct caacatcgcg cggaacggca
    28381 atatccacca gcagcattgg ttggttgcga cggcttttta atgcccgctc caccatgcct
    28441 ttcccgataa tcggtaacgg gctggcggtg gaactaatga tgatatcggc ttcgcgcaga
    28501 cgctcgtcga tatcgctcag ggcaatcact tccgcgccga cttcatctgc cagaatttgg
    28561 gcacgttcgc gagtgcggtt ggcgataatc atcttctgta ctttgtgttc acgcagatga
    28621 cgcgccacca gctcgatggt ttcgcccgca cccaccagca gtaccgtcac cgtagagagc
    28681 gattcaaaga tctgccgcgc cagcgtacaa gccgcaaaag cgacagacac agcactggca
    28741 ccgatatctg tttcagtgcg aacgcgtttc gccacagaga aagatttctg aaacatgcgt
    28801 tccagttctc tggccttcat atgacctttt tgcgaatcgg caaacgcttt tttaacctga
    28861 ccgaggatct gcggctcgcc aaggacgaga gaatcaagcc cactggcaac gcgcattaaa
    28921 tgactgaccg catcgttatc ctgatgccag tagaggctat tacgcagatc gtcttcgttg
    28981 agattatggt aatcacacaa ccagcgaatg agcgcctctt gcaggtcatc ccgttcttca
    29041 acgctgagat aaagttctgt gcggttacac gtcgacagca ccacaccgcc ctgcaccatc
    29101 ggctgcgcaa gcaggctgtc aagcgcctgc tcgagcttat ccggcgaaaa cgatacacgt
    29161 tctcgcagcg atacaggtgc cgttttatgg ttgataccga gtgctaaaag ggtcatgtct
    29221 gcgggaaata ataccaacgt tgatagggtt agtctgcttg catcatacag gatgcgtaag
    29281 atcaataaaa gagagcgccc ccttttggag taattgctga aagccgttag attctggcaa
    29341 ttaagacaac gtgaacatag acgatggcta acggtaacgc tagcattaag ggttataact
    29401 gcaacgtatc tcaaggactt gtcattatta tgcccctgcc cgattttcgt cttatccgcc
    29461 tgctaccgct ggctgctctt gtgctcactg cctgttccgt taccacgccc aaaggtcctg
    29521 gcaaaagccc ggattcgcca caatggcgtc agcatcagca agacgtgcgc aatcttaatc
    29581 agtatcaaac tcgcggcgcg ttcgcttata tttctgacca acaaaaagtg tacgcccgtt
    29641 tcttctggca gcaaactggt caggatcgct accgtctgct gctaactaac ccattgggca
    29701 gcacggaact ggagctgaat gctcagccgg gtaacgtgca gttagtcgac aataaagggc
    29761 agcgttacac cgccgatgac gccgaagaga tgattggcaa attgaccgga atgccgattc
    29821 cgctcaacag tttgcgccag tggattttag gtttaccggg ggatgcaacc gactacaaac
    29881 tggacgatca atatcgcctc agcgaaatca cctacagcca gaatggcaaa aactggaaag
    29941 ttgtttacgg tggttatgac acaaaaactc aacctgcgat gccagccaat atggaactca
    30001 ccgacggtgg tcaacgcatc aagttaaaaa tggataactg gatagtgaaa taatgcggac
    30061 acagtggccc tctccggcaa aacttaatct gtttttatac attaccggtc agcgtgcgga
    30121 tggttaccac acgctgcaaa cgctgtttca gtttcttgat tacggcgaca ccatcaacat
    30181 tgagcttcgt gacgatgggg atattcgtct gttaacgccc gttgaaggcg tggaacatga
    30241 agataacctg atcgttcgcg cagcgcggtt attgatgaaa actgcggcag acagcgggcg
    30301 ccttccgacg ggaagcggtg cgaatatcag cattgacaag cgtttgccga tgggcggcgg
    30361 tctcggcggt ggttcatcca atgccgcgac ggtcctggtg gcattaaatc atctctggca
    30421 atgcgggcta agcatggatg agctggcgga aatgggactg acgctgggcg cagatgttcc
    30481 tgtctttgtt cgggggcatg ccgcgtttgc cgaaggcgtt ggtgaaatac taacgccggt
    30541 ggatccgcca gagaagtggt atctggtggc gcaccctggt gtaagtattc cgacaccggt
    30601 gatttttaaa gatcctgaac tcccgcgcaa tacgccaaaa aggtcaatag aaacgttgct
    30661 aaaatgtgaa ttcagcaatg attgcgaggt tatcgcaaga aaacgttttc gcgaggttga
    30721 tgcggtgctt tcctggctgt tagaatacgc cccgtcgcgc ctgactggga caggggcctg
    30781 tgtctttgct gaatttgata cagagtctga agcccgccag gtgctagagc aagccccgga
    30841 atggctcaat ggctttgtgg cgaaaggcgt taatctttcc ccattgcaca gagccatgct
    30901 ttaagccggg caagctgagt ttcggtgaca acgtcacctt gttccagacg ttgcatcgcg
    30961 ctctttaata caccgcctgg aaagaatcat gcctggcccg cacagttttc ggcagattct
    31021 ttccaccaat ggacgcatgc ctgaggttct tctcgtgcct gatatgaagc tttttgctgg
    31081 taacgccacc ccggaactag cacaacgtat tgccaaccgc ctgtacactt cactcggcga
    31141 cgccgctgta ggtcgcttta gcgacggcga agtcagcgta caaattaacg aaaatgtacg
    31201 cggtggtgat attttcatca tccagtccac ttgtgcccct actaacgaca acctgatgga
    31261 attagtcgtt atggttgatg ccctgcgtcg tgcttccgca ggtcgtatca ccgctgttat
    31321 cccctacttt ggctatgcgc gccaggaccg tcgcgtccgt tccgctcgtg taccaatcac
    31381 tgcgaaagtg gttgcagact tcctctccag cgtcggtgtt gaccgtgtgc tgacagtgga
    31441 tctgcacgct gaacagattc agggtttctt cgacgttccg gttgataacg tatttggtag
    31501 cccgatcctg ctggaagaca tgctgcagct gaatctggat aaccctattg tggtttctcc
    31561 ggacatcggc ggcgttgtgc gtgcccgcgc tatcgctaag ctgctgaacg ataccgatat
    31621 ggcaatcatc gacaaacgtc gtccgcgtgc gaacgtttcc caggtgatgc atatcatcgg
    31681 tgacgttgca ggtcgtgact gcgtactggt cgatgatatg atcgacactg gcggtacgct
    31741 gtgtaaagct gctgaagctc tgaaagaacg tggtgctaaa cgtgtatttg cgtacgcgac
    31801 tcacccgatc ttctctggca acgcggcgaa caacctgcgt aactctgtaa ttgatgaagt
    31861 cgttgtctgc gataccattc cgctgagcga tgaaatcaaa tcactgccga acgtgcgtac
    31921 tctgaccctg tcaggtatgc tggccgaagc gattcgtcgt atcagcaacg aagaatcgat
    31981 ctctgccatg ttcgaacact aatcgaaccc ggctcaaaga cccgctgcgg cgggtttttt
    32041 tgtctgtaat atccatttgt atgacctatg cctccttcac ctgccattta gttgacagat
    32101 gatgcgctca cggatgaaac attattgtga acaaaatatt ttcctcacat gtgatgcctt
    32161 tccgcgctct gatcgacgct tgctggaaag aaaaatatac tgccgcacgg tttacccgtg
    32221 acctgattgc cgggataacc gtcgggatta ttgctatccc gctggcgatg gcgttggcta
    32281 ttggtagtgg tgtggcaccc cagtacggtt tatataccgc agctgttgcg gggattgtca
    32341 ttgctctgac gggggggtca cgctttagcg tttccggtcc gactgcggca tttgtggtaa
    32401 ttctctatcc cgtttcgcaa cagtttggac tggcaggact gctggttgcg accttgctgt
    32461 cggggatctt tttgattctg atggggctgg cacgctttgg gcgcctgatt gagtatattc
    32521 cggtttccgt caccttaggt ttcacctcgg gtatcgggat caccatcggt accatgcaga
    32581 ttaaagattt tctcggtctg caaatggccc atgtcccgga acattatcta caaaaagtcg
    32641 gcgcattatt tatggcgctg ccgaccatta atgtgggtga tgcagccatt ggcattgtga
    32701 cgcttggtat tctggttttc tggccgcgtc tgggcattcg tttacccggt catcttccgg
    32761 ccttgctggc tggttgcgcg gtgatgggga ttgttaatct gctcggcgga catgttgcta
    32821 ccatcggttc gcaattccac tacgtcctgg ccgatggttc tcagggtaac ggtattccgc
    32881 aactgctgcc gcaacttgtg ctgccgtggg atctgcctga ttcagaattc acgctaacct
    32941 gggattctat tcgcacactg ctgcctgcgg cattctcaat ggcaatgctc ggcgcaatcg
    33001 aatctctgct ctgcgccgtg gtactggatg gtatgaccgg aacgaaacac aaagcgaaca
    33061 gcgaactggt tggacaggga ctggggaata ttatcgctcc gttctttggt ggcattaccg
    33121 ctacagctgc catcgcgcgt tctgccgcta acgtccgtgc cggggcaact tcccctatct
    33181 cggcggtgat ccactctatt ctggttattc ttgccctgct ggtactggca ccgctgctct
    33241 cctggctgcc gctttccgcc atggcagccc tgctgttgat ggtggcgtgg aacatgagtg
    33301 aagcgcacaa agtggtcgac ttgctgcgtc atgcaccgaa agatgacatc attgtcatgc
    33361 tgttgtgcat gtcgctgacc gtgctgtttg atatggttat tgccatcagc gtggggatcg
    33421 tgctggcatc gctgctgttt atgcgtcgta tcgcacgtat gactcgcctg gcaccggtag
    33481 tcgtagatgt tccagacgat gtcctggtac tgcgcgttat tggcccgctg ttttttgctg
    33541 ctgctgaagg cttattcaca gacctggagt cacgtcttga aggcaaacgg attgtgattc
    33601 tgaagtggga tgccgttccg gtacttgatg ctggtggtct tgatgcgttc cagcgttttg
    33661 tgaagcgtct acccgaagga tgtgaactgc gcgtgtgcaa cgtggaattc cagccactgc
    33721 gcacgatggc tcgcgcaggc attcaaccga tcccgggccg ccttgctttc ttcccgaatc
    33781 gtcgcgcggc gatggcggat ttataagtac gagattgacc agtcagagca aactgactgg
    33841 tcagtaaact gcagtatttg ttagctatga cggcgattat cgctacggcg gcaacgtttg
    33901 tcatagtggc gaacccacca gtaacggtcg cacacctgtt catgcccgcc aacacgggca
    33961 cccgccagcc agagaatggc accgacgaaa atacttagca ctgcaccatg tgcgaaatac
    34021 tggggcatat taaactgtgg taactggttg aggattgaat accccacacc gaccaccatt
    34081 accaccagac ccaaccccat gagcacgtta ccgagtaacg aagcgttttt gcgtttcata
    34141 tgtcacctcc ggaactttct gggttgtaac agggaatacc cctcttcctt atgtgtaaag
    34201 tatagacaac accctgtggg ttatgtgcgg gcgtgatcac aattacaacc cttatttcaa
    34261 caaaacttta caaataaacg cctgaacacc ttggctttct aatagtccac tcaggcaatt
    34321 attgcgttat ctgcatttga tacgcagttt tttgtcaagc ggggccgcaa ccagtaaact
    34381 acgcgccagt tatgtacaca ctcaggacaa aaaaacgtga cgattaaatt gattgtcggc
    34441 ctggcgaacc ccggcgctga atacgccgca acgcgacata atgctggtgc ctggttcgtt
    34501 gacttactgg cagagcgatt gcgcgctccg ctgcgcgaag aggctaaatt ctttggttat
    34561 acttcgcgag tcacccttgg aggcgaagat gtccgcctgt tagtcccgac tacatttatg
    34621 aatctcagcg gcaaagccgt tgcggcgatg gccagttttt tccgtattaa tccggacgaa
    34681 attctggtgg cccacgacga actggatctg cctcctggcg tcgccaaatt taagttgggc
    34741 ggtggccatg gtggtcacaa tggactgaaa gacatcatca gtaaattggg taataaccct
    34801 aactttcacc gtttacgcat cggaattggt catccaggcg ataaaaataa agttgtcggt
    34861 tttgtgttag gcaaaccgcc tgttagtgaa cagaagttaa ttgatgaagc catcgacgaa
    34921 gcggcacgtt gtactgaaat gtggtttaca gatggcttga ccaaagcaac gaaccgattg
    34981 cacgccttta aagcgcaata agtcgttgtc tgcggcattt ttgccgagtg ccgtgtataa
    35041 taggcaaagt tatttccatt tctgcaatct gttagcaata acaggttgat tattaagata
    35101 ttaaggtgat ttaaatcatg ggattcaaat gcggtatcgt cggtttgccc aacgtcggga
    35161 aatctaccct gttcaacgcg ctgaccaaag ccggtattga agcggccaac tttccattct
    35221 gtaccattga gccgaacaca ggcgtcgtac caatgcctga ccctcgcctg gatcaactgg
    35281 ctgaaatcgt aaaaccgcag cgtacgcttc ccacgaccat ggaatttgtc gatatcgccg
    35341 gtctggtaaa aggcgcatcg aaaggcgaag gtctgggtaa ccagttcctg accaacatcc
    35401 gtgaaaccga agcgatcggt cacgttgttc gctgctttga aaatgacaac atcattcacg
    35461 tttccggcaa agttaacccg gcggatgata ttgaagttat caacaccgaa ctggcgctgg
    35521 cggatctcga cacctgtgaa cgtgcgattc atcgcgtaca gaagaaagcc aaaggtggcg
    35581 ataaagacgc gaaagctgag ctggcggtcc tggaaaaatg cctgccccag ctggaaaacg
    35641 caggtatgct gcgcgcgctg gatttaagcg ctgaagagaa agcggctatt cgttacctga
    35701 gcttcctgac gctgaaacca acaatgtaca tcgccaacgt caacgaagac ggttttgaaa
    35761 acaacccgta tcttgaccag gtgcgtgaaa tcgcggcgaa agaaggttct gttgtggttc
    35821 cggtttgtgc tgctgttgaa gcagacattg ccgaactgga cgacgaagaa cgtgacgagt
    35881 ttatgcagga gcttgggctg gaagagccgg gcctgaaccg tgtgatccgt gccggttata
    35941 agctgctgaa cctgcaaact tacttcaccg ctggggtgaa agaagtacgt gcatggacca
    36001 ttccggttgg tgcaaccgcg ccgcaggccg ctggcaaaat ccatactgat tttgaaaaag
    36061 gctttatccg tgcacaaacc atctcgtttg aagatttcat cacttacaaa ggtgaacaag
    36121 gcgcgaaaga agcaggcaaa atgcgtgcag aaggcaaaga ttacatcgtt aaagatggcg
    36181 atgtaatgaa cttcctgttc aacgtctaaa taaaatttgt tgtctcatga ggtttcattg
    36241 aacttcatga gaatcaaaaa aaccattaaa tccacgcaat tgcgtggatt tttcatttca
    36301 tagagtctca attcatttcg tgataacaca gtcaaaaatg agtacatgga tgagtacaat
    36361 atccttccat cttcatttta agtgagtaca ataacggtat aataaataaa caaggccccg
    36421 ttatgctcac tgatacgcaa tgccgcactg ctaaagcgaa agaaaaactc tatcggctca
    36481 atgatttcaa cggtctctac ctcgaagtta aacccaatgg caaaaaggcc tggcgctatc
    36541 ggtttaaact caacggtaaa tccagcatgt ttgcgctagg tgagtacccg acggtcaaac
    36601 ttgccgaagc tcgcgagaaa tgcgagcaag cgcgtaagca agtcgcggat ggagttagcc
    36661 cgacacaggc tcgccagtta aataagattc gcaaggtcaa cgacgcatcc aacacctttg
    36721 agctgatcgc taaagagtgg ttgcagatga aagactgggc cgaaatcacc aaaacgcgcc
    36781 gactggatat gcttgaacgt gtggtttttc ccgccatcgg taagctccct gtcagagaga
    36841 tcactccaca ccatatcctt aaaattcttc aggaaacagc caaacgagga gcaccgacag
    36901 ttgccgctga agcccgtcga accatttcat cagttttcga gttggcagta gcgacactta
    36961 gagctgatag tgatcctgtc tggcccgtgc gcaaggctct gccggccaat aagacacagc
    37021 acaaacaagc actgaatcct cagcaaatcg gaaagttatt aagctgtttt gacaatagtc
    37081 gtggctcgta ccaggttaac tattgcatgt ggcttatgtg gtggacattg gcgcgtcctg
    37141 cagaaaccac cgaagcggaa tggatagaat tcgatcttga taacgccctg tggaccattc
    37201 cggcagcgcg gatgaaagcc cgaagagaac acgttattcc cctgccctct caagctgtca
    37261 aaactcttag aacgctacaa ggattaaccg gacatcggca gcaccttttc ccgggcaggg
    37321 ataatccgaa aggcccaatg acatcacatt ccctgcgcca gctacttaaa agcttcggct
    37381 ggagtggcat ttatagcccc catgctacca gaactacagg aagtacgcgt ttaaacgaaa
    37441 tgggctatcg gcctgatgct attgaggccc aactcgcgca cgctgatacc aacaatgttc
    37501 gtcgcacata caaccatgca acttaccttg atgagcgtaa agtgatgatg caggaatggt
    37561 ctgatatgtt ggacaaatgg gtagcaggat ccgagtagaa cttactgcac ttagtgaacc
    37621 acgaggatag aactcattct tcatgggtcc actttgtgcc aggagcagac gtttaaatat
    37681 tttgcctgca tttttgcata gacaacgctt attagacgga ttaatccata tttgtagcaa
    37741 atgcaaatcc caccagctgt acctacaacc tattgttagt tgtgaaaaat cgatgtagtg
    37801 ttctacacat caaatttaca aaggcggaaa acaccatgtt taaatatgga gctttccgcc
    37861 aaataagcgt tatgcctatt caaaatgata atagagaatg tgtgaatgga tgcgagatac
    37921 gaagaaaaga ctttcgaaag ttacttcaac aatgagcttg atagaaaaac atctatctat
    37981 ttcccccttg gccaggtgca agaaggcgtt ttaggcttgg actccgttgc tcattctaga
    38041 ggatggtttc tgtggcgaaa gctcggatat ccattctggc tctctccgca attttcaggc
    38101 gttgaactaa gggaaatcgc tcatgaaatg gagcattacc ttggccgaga ggttaagaac
    38161 ataccgacca tgaaagttaa cttgctattt cagtataagc gtccgcaata cataacgatg
    38221 tcaagtggtt ctgagtggca cttatggaat cagaagtatt tccgctatga cctgtacact
    38281 cagcaacata ccttgctctc ccacatagaa actaaatttg gtaacgatgc cgtagtcctt
    38341 tacgctgccc cttctgtcgt agatgttggc gatttggtta acctaaaaag ggctgggtca
    38401 atcattgatc acactaactt tagacgcgcc agagaattgg atgggcacca cagaaacacc
    38461 tacataaagg caggcacata ctcgcaagca tgtagtgaac cagaaatgat tgaaaatttt
    38521 aatctaattg aaatgattga agcaatggaa ccacgccaat cagaagataa cgttaatcta
    38581 atcattaact tttcaaggca gattaattca gccatgaagg atgtcgaagg gattggttat
    38641 ctgaaaaccg catttgagaa tcgtatggat gaatttagag attacggact tcaacagttc
    38701 gtactgttct actcaatgct tactatggca atattcagag aggttaccgg ctgccaatgg
    38761 ttaataccat ttgacggacg aaaaaatgca taacactgca tcgcgcactt cgtgcgcagg
    38821 acctcgctac gctcggccgc tgttggcagc gttgatgtcc gctactcgct caaagcaaac
    38881 ccaatgacca cttagcctgt ccgttgcgtg ccagaagccg acttttggta gttgtcagta
    38941 ggatggtatt tgagcagaat gagacagcct ttaaggctgt tcgtttttta tacaacaaca
    39001 caaggtctga atggggctac tggcccacaa aagaaaggat gtacgagatc gagctatgcg
    39061 tattcatcag cagaataagt cccgtacact atatcgcagc gtcaacacga cgacgcggca
    39121 ccattctaat aatccgggtg ctgagtatcg gtgggaacga aatcgcaaaa aagtcggaga
    39181 tgagctactg gtaaagcgtg agacaatgct tagcagacag aagcgtggcc gagactacac
    39241 accattgttt tattttctga tcaaagagat tggcaagccg tggaatgaaa tattcagcga
    39301 agtatgtgga cgtcttgata ccactgagcc ggtattctgg ttggtcgcgc tacatgagca
    39361 tcagcgaagg gatttagtct gcattggtgc aagcagtttt tacccaggtc tgtttgttga
    39421 tgagaatgga attctgcaac aggtaaacct ttcaatcaca agagatgacg ttaaggtgac
    39481 atgtcgttgc tgcacacaca cttatattgg tgaacctgta ccttggatag attgagtgac
    39541 accacctatc ttatcttgga tgcgatcatt gtcagcagta agagtgcttg catacatccg
    39601 ttactcactt actccgggcc gttagccctt ccgcaatgtg ccagaagcgg acattgctac
    39661 atcacaatgc gttatggtca acatcagaat gcagcccttg tgttgtgacg tgtggtctgg
    39721 cctaaacgca gttgtactac attacctcgt ggggtcagcg acggccccga ttcagttcac
    39781 gtacacaggg atcatactca tctgcatagc caccaaagtc atggctgggc atgaagtacc
    39841 acttttcgcc gttccaacca gcgatccggg tggtcggttt ggttttattc agaacaacaa
    39901 tacaggcgcc gacgggagac cctggaggaa gaagtcgttg caccacacac tcacgattgc
    39961 caacatcaat ccagtctttg acgtgaattt caggatggtt cattgtttat ctccatgtga
    40021 tggatttgat tatcgtaatg tatccgatta ccgtgcaaga tcatgtctcc tgtcgccttc
    40081 ctgctccctt gaggtggcgc tgccttggta cagtcagcac tctgaatgtc aggcccagcc
    40141 gcgaggccca gaagctcatc aggtcgctgc ggcaggggaa aacggaccgg gtcacagacc
    40201 gtaatcgcct gctggcggtt attggccctg actggagccg cactgaaaac tgaagcgcat
    40261 taatacactt gcgcccccga caggtcaggc aatttcttcc agcgcatcgt catttgccgg
    40321 tggaggagga agtataagcg cgtcgcactc cctgataaca tattcaggaa tgagatcaaa
    40381 ccgggcagga tccagctgac agataaattc attttcaatg tggtaggtct cattcatgaa
    40441 tttacgtatg actgcgtttt cgactccggt ctgaagcaac ctgaacacct gcagtttctc
    40501 gtagccatta cggcagagca gataaagcgc acgtatacga tccgggtcgg tgagctgaac
    40561 gaaagtggcc tggtagtcaa agccgggaat gcgatcggcg attgcctggc agccgctggc
    40621 aactttttct gcggacattt caggatgtcc cactccctgc acaacgggtt cacgggtgtc
    40681 gatgggcgtt tcacggtgat gaaaaaggtt tgacagcacc tgataggcat caccgaggtc
    40741 gtccataatt tcataatgtc ggcgaagata gatcaacttg atgatgtctt cactatcaga
    40801 gtcagtgaca gactggcaga tctgagcaaa agtgcggata tcactttcac cgatgagctg
    40861 ctcggtgatg cagcctgcgc agtagcgcaa gtgtgaggcc gtaaccagat tactgaacag
    40921 cttcctgacg gacttcagcg tatcaataat aggctcaaca tcgtgagtca gcatcagtac
    40981 cgtttcattt ttcaggcact caccggtatt gcggcgaaac agcatctcca ggatggcaaa
    41041 tttcttgttc ttatcaaacg atgaaatcgg gtcgtcaaga atgatcaggc ctggcttctt
    41101 ggctaggcat tcatacataa acagaacgat ggcaaaggcg ttgcgttcac cgtagctgag
    41161 atgctggctg ccgccgctga cgtagccttc aaagtcttcg tggcgcagtt tcagccgaca
    41221 tttatcgcct tcccccgtga tatccacctg ataacgatag ccagcgtaag ccagaaaggt
    41281 attgatatcg gttttatgct tgaggatcag cttctgcatg ccctgacgct gcttatttat
    41341 ttgaccctgc aggcgtccgg cctgcgtcgt cagatcgtct aaagaggtat tgagactggc
    41401 tacggtgcgg gccgttttat ccgactgcag ctccgggaaa aacttcacgt ctaggcgaca
    41461 ggcttccagt gcagccttga cgttggttga agcgctgaat gtaaagccgt taagagtctt
    41521 aagggtattc agcatattta tcaggctgtc tgtctgcttc ttcactgtca cgagatattc
    41581 ttcgtgctgt ttttccagcc cactttttag ggttgtaata tcagtgaggc gggcacgggc
    41641 agactctgaa aaatattcgc cgagtttatc tagcacgccg atcaggccga tcaggttttt
    41701 aatgacagcc ttatcatact ccgcgctgac gcggctaatc tgctcggcct tttcacggga
    41761 gtcgccagta cagaacggac agcagccgtc ggatagcgcg gagaatttct catacccccg
    41821 ggtctgccac tcgatccact ctacgctgct tttactttgg atgtacggct tataagattc
    41881 caaaccgtcg ggaatgtgct gaagcttgtt gccggctgat aagcctttca taccggtaga
    41941 cgtttttgca atcccggtac tactcagctt aaatgcggcg ctgagttccc ccaggtgcgt
    42001 gatgaattct tcaagcccga cgttatcagc aaactgctgc cgtatggcca cgaccatggc
    42061 ttcgatttcg cgttctgtct catgatacgc ttcacttttg atgaagatgt caaaactatt
    42121 acttactaac tcgtctggtt gaaaagtgaa ttgatcgaca tatttttcat taaagcacat
    42181 gacgttttgc aggccatcga caccagttac cctaggctgt actgcatcgg gattagaacc
    42241 acggtatcta aacggaagca ggtcgctgag accttgttca tccccgttta ccgtacactg
    42301 aatcgcgcgg gaaatggtgc tttttccggt gccgttaggc gcaaatttaa tatttaattt
    42361 ttttactgcc agagttatat ttgctttatc gatgttatta cagcagttaa tttcaatttc
    42421 catacctaat cctttacggc aaagacactg agcaggcccc gtatattgca ggcccgatta
    42481 attatttaag ctgaagccag tacatataag caccgtttca tttttgggta aagcactccg
    42541 ggattcgccc ttggtaccgc agcgccggag cagttatttt atagagcgta tgtacggcgc
    42601 ttgtgatggc ttttttgtta agctggcaat agtgaaagca cggcaaaggc atactataat
    42661 gatcaatata tagcccatac aaaagaaagc ggtgttccag tgccctggtg aagggaaaag
    42721 catcagcacg ctcgcccgag aattcgacac cgcaaggcag acctttctaa gagtaaaagc
    42781 ggctatggaa gaagccgatg ctcgctcgtg ggctgctttg caatgtatgt ccgcttcgtg
    42841 ccaggagcgg accttgctga aggagacaga taataataaa tgggttgagc tggttaccct
    42901 gactacagtt ttgcaattat gataaagtgt tggccaacgc gtaatagtaa ttcaaatagg
    42961 gattggcagt gagggacgat ttctcaaaca aaattaaaca gaggttggcc gaacgcgtag
    43021 catggctttg ctccaatccc gattgcagag ttgtgactgt tgggccccat acagatccta
    43081 caaagcgagt taatgttgga caggcatgcc atattgaagc cgcatctgaa ggtggccccc
    43141 gctacaacaa ggaaatgcaa aaagatcaaa gatgctcttt tgacaacggt atttggcttt
    43201 gctctatcca tgcaaaagaa attgatgtag atccagaccg cttctctgta gagcttcttc
    43261 gtaaatggaa gcttacagct gaacagtatg cgctgagtaa agtaggcaaa gcgagatatg
    43321 atgtatctca ggatgtcttt acggaaaatg taaatcgcca tcgtgaactt ttttcaggta
    43381 ttcgtgatat tgaatatttc agtttatata gggactcaaa tgataaatgc ttcactttgc
    43441 gcggtgttgg gcctttaaat ataatcgtaa aagatcgtag aatagatatc ttttttaaag
    43501 attcattcaa tcccatcaaa tatagaaatg attcttacat aggattaata tgcttgccag
    43561 taaaggaatt aattgattat gtagtattat ctcacgagtt tgatgaaaca attgagtcct
    43621 ttaatatgac atttaacttt agtccaaact cgttgaatga aatgtatttt tcgatccaca
    43681 cggacacggt taacgttaat ccacacatgg atggtattag ttattatggc gattacacag
    43741 tagagatgga tgaattaata gatgatttag gtagagctat acctccttat cggcaggaca
    43801 tttaccttaa gattattgta gcaatgtaca acatttaccg acgaattgta acatacaaaa
    43861 cagaaggatt tacttaattt tttgtgaact gtaagccacg cgaagcattt aatcaaagtt
    43921 aaatatttta taatttactt ttgtcttcaa aaaaatagat tgagccgtga actaatactt
    43981 tgcagatctt atatgctata ttatataccg caatggtata tatcttatct atgaaagtgc
    44041 aacggatggc cagatcctcg ccgatcttag catggtagta tttactaata catcaagaag
    44101 cgaacttccg cttctcgctc aaagcagacc ttctagtcca gcaagcctgt ctgctccctg
    44161 ccatgagcgg acaaaaagca gtaagaaaaa aggatagata agatacaatc tcagtcaatg
    44221 attaggagtc agctctattt agaaggtcag aaatagtaat tcctcacccg gtaaacatca
    44281 tattatcggg tgaggttgct acgtttccag atcaaggtat ctgtgactta cttccgcttt
    44341 gtttttcatg aatctgaata tcaatcgcag aatcatcact acgtacctcg tagtaacgtt
    44401 caggcttccg ataaacgttc accatctgat ggccagtcga gaatatattc tcttcaagat
    44461 atcttgcatt gccccaaatc atcttctcaa tttcattcga tccatattcg tagtacgcat
    44521 cacttgcttt caccagcctc tcaatctcag taactttgcg taaatttcca atattctctg
    44581 tttcagcatc aggcataaca atgaacaagt tatcgcgtgc gcgactgatc gctacattaa
    44641 gaatattctg tttattcagg aacatccggg agtcacttga aatgtttggc ggcggattaa
    44701 gcaccgcaat aataatattg cattcatccc cttggaagcc gtgtatcgta ccgacctgaa
    44761 catttacagt atcaggtttg gtaagccatg aatcattcaa cttgctcagt agattagctt
    44821 gagcgcgata aggagcgata actcctatac ggattatctc tgaatttttt ctctgtatct
    44881 tccctgacag ccagcgaaca aactcgaaag tgaacaatgc tgaataagtc tgataaggtg
    44941 ttccgctttc cattcgtttt gcccggtaaa tactttcata tttactgacc ggaaatttga
    45001 tgagatttat cggcatagca tcgaattcgc agaaactaaa cgaacaggga gattctgccg
    45061 tacggtgatg ttgcaagatc ccgtcataag tgaaacggct ataaacttca ccaattgcag
    45121 gaatactacg gtactgtgtt tccagattga ctatcgggta atcatgaggc tctgtcgacg
    45181 gctgcgcaaa agaacctcgc ttattgagac cgaccaacgt gtaaatgttc tcatctttcc
    45241 attcttctac agcaacaatc ggcccgatct ggaaaggatc tccagcgata atgaactttc
    45301 gtgggtgtat gcggtaaagt ggatagatga tattggctaa cgaaatcatt gacgcttcgt
    45361 caatgacgac ggtatcccac tccatttcat aaagtttctt accatactca ccagtaaatc
    45421 catcataggc gaagcgagca atggtggtga tcgttataga gcgatccaat gcgccgatgt
    45481 tgaatgttct gtcccgccat actccagcgt tttcaatacg cacatcaaca gatgatccga
    45541 aacgcaccaa ccactcctga tatgaggtat ccccaaccat cgcctccatg acgcgggtcg
    45601 tcaacacatc tgcagccttg ttggttggcg ctaggacaag cacgttttcc ttcccactac
    45661 ccttcattct tggtatcagt actttttctg cgagatgagt cgtcttacct gttcctggtg
    45721 gaccaaacac aaaatcaatg tcagacgtca ggcccgcttt catcgcaaac gtttcgccta
    45781 atctcaattc ctggaatcgt tccagcaaca cctgctgcag gaacgatgga ttctggactt
    45841 caatacgtgc ttccaccacc tcttccagtg ccatcccttg taaatcatcg gcagattcca
    45901 gtttaccaag taatgaaaat tctctggccg taaacgactc aatatgtaac tttcctgtac
    45961 gcccattacc aaaatcgaga tccacacgta tgccggaaag ttcttcaata gattgcggaa
    46021 tgaagcgact gggttctttc agtacgatgg ttctggatga ttgttcatcg tgctccacct
    46081 tgccaaagcc aatagaaata gtcttactgt cagcattctt tgttctggtt gctaagcact
    46141 caagttccag caaagccaga aaccagccat aactgtaacg aggtaattcg ttggccttgt
    46201 catataacgt ctgctcatgc tccagacagt caatttcact ggcataacgg tctttggcca
    46261 agtcaatttt tttgccgtag tcaaccgttt ttggcgtgta atcgtctgtg tcgatgcttt
    46321 cgtcgctttg acgatctgct gccgcagaat cgtctttctg cgggccatcc gagtgggtgt
    46381 cctggatgga tggacggcgt cgagcaatat cacggatgaa tggtgagtcg gccgctggct
    46441 gatctttgtc aacgggctcc acgatgggtt gggatgaatc ttgctttttt cgcttagcat
    46501 cttcaatcgc tatgcggatt tcgtcctctg acaaaccgga gtgttcaatt gcatccgcca
    46561 gtctaatttt tctggcttcc tcggggctta aatgtgtctc atcgcgaatg tgcaaaaagt
    46621 tgatgagcat ctttgcttct gcactgacta tgtcgtattg ctctgcaagc gtttgaatcg
    46681 tgatctcttt ggctgaaacc catgctccat ccttatcaag gatccaacgg gttgtacgca
    46741 atttttcttg ctctgcggat tcgtaagact cgcttcgatt tgtataataa aaccatacat
    46801 gcttgccgct aagctggtga atgaattgtg gaagtaattt ccacagcagg agtgaccgtg
    46861 gcaagtcaat atttgccatg atctgctgac agccatcaag gtttttttca tacagcttgt
    46921 gcgaatgtcc ctctaaggat aagtgtcgat cgcgccgctc ttgccactca atatagcgct
    46981 cttcggtgat tattttaggg cgatccgcaa ttcccagttt tttgaaaaag tccttgagtg
    47041 caggatattc tttttcgcta aacatctcgt ggtatttgtc caaaaacaga aatggtgttt
    47101 ctggcttggt cgtgaaccag gtttgcaaat cctcggtcgg catatagatg tcatcggctt
    47161 tgccatgaga aaactcattt ttcccagccg ttgtgtagag aagaaaagct ttatccttaa
    47221 taagcttaat aaattctgaa acgtcttcgt ttttacactc tttgaagtaa cggaagaatc
    47281 ggccgaaatg ggtgtctgcg ttaacagggc tgctggtgct gttataggcc gggaggatct
    47341 tgttgtagat ctcatcacgc aggcttggct tcttgattcc aaatttttca ataaactcac
    47401 gagtgctctc gtcggacagc aattcggcgt tgacggtctt gtagccgtca atatcgtcgt
    47461 ctggtagaaa caggatgagt tgattccagg cgtcaaaggc cgggattgcc tgaccttgct
    47521 ggtcaagaaa gataggctta tctttcacaa atttttggta agaatcgcgt ccggcaaggt
    47581 atatatagag tctgtgcagc cattctattg actgactggc gatgaagtca gcggtaattt
    47641 tcttaagggt agcttcggga tcaagacttg atacgatcag attaggttct cttattgacc
    47701 ataccctagc atcgccgccg tcgatgtatt cggccagggc cttattaaca ttttgtacgt
    47761 ctttcttgcc acgactacga aaaatccagc ttgcgttctc tgtacccgtc aattgcgcca
    47821 gttgcatgtc agagaataat tcaactagtt cactgtctgc tgcccaatag gagcagtttt
    47881 ttggtgagta gttggcattg gcggcgggga gcaacgtgtc ggtctggagt ttggttttga
    47941 tagcagaata aaacggcttg aacgaaattt ttctccggtc gtctagttca ctgaactgat
    48001 tttcgtcata gggaataatg tcaaagatgc catcatcgag cagtttttta tcacgaataa
    48061 tgggtaaact atccgctgta agtttcgcca gctgctgaat cagttgctgg ttatgctttt
    48121 ctcctgcttt gataccttca cgactatccg ttaacagaaa tggcgcgtga aggataaatt
    48181 tcagatgcgt tatttctttg gtcgggaaaa aacagaacgc tggatgttca acaggctcga
    48241 gtttcccgtc ttctccaatt gcatacccga ttgtgcaggc atttctgttc gcgtgattgt
    48301 gtgtaaatag gagtaattga tgaatagcct tactgtcacc cacttctaat gtcagcacca
    48361 gtttttgcgc cagaatgtct tcttgctcca gttcctctac aattttttta gtatatctgc
    48421 cagtagtttc acctacggta aaggataccg attttaacgt cgaaaggaat aagacaggaa
    48481 attcaagcgc tttcaatttt tcaaaaattt cgttgtagct ctccaggggc gttttttctt
    48541 tatggtcaaa cggaaagaaa aaaacggtat ctgaagcatt acgccaatca aggtcagcat
    48601 ttagcatctg cggcacgatg aaacgttcga tcttaaaacg aattccaggg tcatatatgt
    48661 gtggggtttg cgtgtattga aagacagctt taaatcctac accgaactta cctatagacg
    48721 cctccgtctt acttgagtta gcgatggagg tgattgaatt aatatgtcct aaagcaccgt
    48781 tgccagcgtc ttcaccttca cagtgcgggt cagatacgga aaagtgaata gagccattat
    48841 gaatgaaata aagtccatct tgatcaaggc ggaagctcac cgatgttgct ctgacatcat
    48901 ctgcgttttg caaaagctcg tagatgaaat gcgcctggtc ggaatacttg tccacaacgc
    48961 tgcgctggat accacgcatt gatggttttt ccagagtgtt agcattatcc gcacgatctt
    49021 gcattagggc gtaaaaccat tctttttcct gttcggtcaa tccatcttca tgcgatttca
    49081 tctaaaaatt aaccttaaag tttagttgtg ctgtgttcat tcaaaaacaa actcagacga
    49141 tattcaattc actactggag aaatagatcc tacttttttt agtagcatgc cctatatagt
    49201 tgcatgaatc gacacgggtc taacagacac ctcagagtca tttttggact gaccccaccc
    49261 cggtagacga tcctgcccta tagttggact gccccttgct cttgagtagc gtatggcttt
    49321 caacatccta gaaacctgca cggcatccgc acttgccgta ctcagtcaaa accgcgttgt
    49381 gtggaactgg ctggcccttt gtaagtatcc gcttaactaa tccattcact tttagagaat
    49441 tctcagtgaa cggttcaggt atcctataag gccaatgtcc gcttttcgct cacagcaggc
    49501 cttaagccca ctccgcttcg tgccaaaagc ggcagtagct aatagtcgat tgcgtggaac
    49561 aactgaaagc aaatcaaata gccgctattg acacatgatg caaatacccc gaaagagcgg
//
LOCUS       DADXDL010000023        49576 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.023, whole genome shotgun sequence.
ACCESSION   DADXDL010000023 DADXDL010000000
VERSION     DADXDL010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 49576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 49576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..49576
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.023"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            49..909
                     /locus_tag="IRB70_001637"
     CDS             49..909
                     /locus_tag="IRB70_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A broad-spectrum beta-lactamase TEM-1"
                     /protein_id="HBC0631561.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGY
                     IELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVE
                     YSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRL
                     DRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPL
                     LRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIA
                     EIGASLIKHW"
     gene            complement(1089..2603)
                     /locus_tag="IRB70_001638"
                     /pseudo
     CDS             complement(1089..2603)
                     /locus_tag="IRB70_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349194.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
     gene            complement(2743..4083)
                     /gene="gntU"
                     /locus_tag="IRB70_001639"
     CDS             complement(2743..4083)
                     /gene="gntU"
                     /locus_tag="IRB70_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate transporter"
                     /protein_id="HBC0631562.1"
                     /translation="MTTLTLVLTAVGSVLLLLFLVMKARMHAFLALMVVSMGAGLFSG
                     MPLDKIAATMEKGMGGTLGFLAVVVALGAMFGKILHETGAVDQIAVKMLKSFGHSRAH
                     YAIGLAGLVCALPLFFEVAIVLLISVAFSMARHTGTNLVKLVIPLFAGVAAAAAFLVP
                     GPAPMLLASQMNADFGWMILIGLCAAIPGMIIAGPLWGNFISRYVELHIPDDISEPHL
                     GEGKMPSFGFSLSLILLPLVLVGLKTIAARFVPEGSTAYEWFEFIGHPFTAILVACLV
                     AIYGLAMRQGMPKDKVMEICGHALQPAGIILLVIGAGGVFKQVLVDSGVGPALGEALT
                     GMGLPIAITCFVLAAAVRIIQGSATVACLTAVGLVMPVIEQLNYSGAQMAALSICIAG
                     GSIVVSHVNDAGFWLFGKFTGATEAETLKTWTMMETILGTVGAIVGMIAFQLLS"
     gene            complement(4087..4614)
                     /gene="gntK"
                     /locus_tag="IRB70_001640"
     CDS             complement(4087..4614)
                     /gene="gntK"
                     /locus_tag="IRB70_001640"
                     /EC_number="2.7.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417894.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBC0631563.1"
                     /translation="MSTTNHDHHIYVLMGVSGSGKSAVASEVAHQLHAAFLDGDFLHP
                     RRNIEKMASGEPLNDDDRKPWLQALNDAAFAMQRTNKVSLIVCSALKKHYRDLLRAGN
                     PNLSFIYLKGDFDVIESRLKARKGHFFKTQMLVTQFETLQEPGADETDVLVVDIDQPL
                     EGVVASTIEVIKKGK"
     gene            complement(4753..5748)
                     /gene="gntR"
                     /locus_tag="IRB70_001641"
     CDS             complement(4753..5748)
                     /gene="gntR"
                     /locus_tag="IRB70_001641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001693277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate operon transcriptional repressor GntR"
                     /protein_id="HBC0631564.1"
                     /translation="MKKKRPVLQDVADRVGVTKMTVSRFLRNPEQVSVALRGKIAAAL
                     DELGYIPNRAPDILSNATSRAIGVLLPSLTNQVFAEVLRGIESVTDAHGYQTMLAHYG
                     YKPEMEQERLESMLSWNIDGLILTERTHTPRTLKMIEVAGIPVVELMDSKSPCLDIAV
                     GFDNFEAARQMTTAIIARGHRHIAYLGARLDERTIIKQKGYEQAMLDAGLVPYSVMVE
                     QSSSYSSGIELIRQARREYPQLDGVFCTNDDLAVGAAFECQRLGLKVPDDMAIAGFHG
                     HDIGQVMEPRLASVLTPRERMGSIGAERLLARIRGESVTPKMLDLGFTLSPGGSI"
     gene            complement(5972..6667)
                     /gene="yhhW"
                     /locus_tag="IRB70_001642"
     CDS             complement(5972..6667)
                     /gene="yhhW"
                     /locus_tag="IRB70_001642"
                     /EC_number="1.13.11.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quercetin 2,3-dioxygenase"
                     /protein_id="HBC0631565.1"
                     /translation="MIYLRKANERGHANHGWLDSWHTFSFANYYDPNFMGFSALRVIN
                     DDVIEAGQGFGTHPHKDMEILTYVLEGTVEHQDSMGNKEQVPAGEFQIMSAGTGIRHS
                     EYNPSSTERLHLYQIWIMPEENGITPRYEQRRFDAVQGKQLVLSPDARDGSLKVHQDM
                     ELYRWALLKDEQSVHQIAAERRVWIQVVKGNVTINGVKASTSDGLAIWDEQAISIHAD
                     SDSEVLLFDLPPV"
     gene            complement(6790..7827)
                     /locus_tag="IRB70_001643"
     CDS             complement(6790..7827)
                     /locus_tag="IRB70_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBC0631566.1"
                     /translation="MVINCAFIGFGKSTTRYHLPYVLNRKDSWHVAHIFRRHAKPEEQ
                     APIYSHIHFTSDLDEVLNDPDVKLVVVCTHADSHFEYAKRALEAGKNVLVEKPFTPTL
                     AQAKELFALAKSKGLTVTPYQNRRFDSCFLTAKKAIESGKLGEIVEVESHFDYYRPVA
                     ETKPGLPQDGAFYGLGVHTMDQIISLFGRPDHVAYDIRSLRNKANPDDTFEAQLFYGD
                     LKAIVKTSHLVKIDYPKFIVHGKKGSFIKYGIDQQETSLKANIMPGEPGFAADDSVGV
                     LEYVNDEGVTVREEMKPEMGDYGRVYDALYQTITNGAPNYVKESEVLTNLEILERGFE
                     QASPSTVTLAK"
     gene            8161..8649
                     /gene="yhhY"
                     /locus_tag="IRB70_001644"
     CDS             8161..8649
                     /gene="yhhY"
                     /locus_tag="IRB70_001644"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBC0631567.1"
                     /translation="MSEIVIRHAETRDYEAIRQIHAQPEVYYNTLQVPHPSEQMWLER
                     LTARPGIKQLVACIDGIVVGHLTIDVQQRPRRSHVADFGICVDSRWKNRGVASALMRE
                     MIEMCDNWLRVDRIELTVFVDNAPAIKVYKKFGFEIEGTGKKYALRNGEYVDAYYMAR
                     VK"
     gene            complement(8710..10455)
                     /gene="ggt"
                     /locus_tag="IRB70_001645"
     CDS             complement(8710..10455)
                     /gene="ggt"
                     /locus_tag="IRB70_001645"
                     /EC_number="2.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyltransferase"
                     /protein_id="HBC0631568.1"
                     /translation="MIKPTFLRRVAIAALFTGSCFSTVAAPPAPSPVSYGVEEDVFHP
                     VRAKQGMVASVDATATQVGVDILKEGGNAVDAAVAVGYALAVTHPQAGNLGGGGFMLI
                     RSKNGNTTAIDFREMAPAKATRDMFLDDQGNPDSKKSLTSHLASGTPGTVAGFSLALE
                     KYGTMPLNKVVQPAFKLARDGFIVNDALADDLKTYGSEVLPNHENSKAIFWKEGAPLK
                     KGDKLVQANLAKSLEMIAENGPDEFYKGTIAEQIAQEMQKNGGLITKEDLAAYKAVER
                     TPISGEYRGYQVYSMPPPSSGGIHIVQILNILENFDMKKYGFGSADAMQIMAEAEKYA
                     YADRSEYLGDPDFVKVPWQALTNKAYAKSIADQIDINKAKPSSEIRPGKLAPYESNQT
                     THYSVVDKDGNAVAVTYTLNTTFGTGIVAGESGILLNNQMDDFSAKPGVPNVYGLVGG
                     DANAVGPNKRPLSSMSPTIVVKDGKTWLVTGSPGGSRIITTVLQMVVNSIDYGMNVAE
                     ATNAPRFHHQWLPDELRVEKGFSPDTLKLLEAKGQKVALKEAMGSTQSIMVGPDGELY
                     GASDPRSVDDLTAGY"
     gene            10575..11015
                     /locus_tag="IRB70_001646"
     CDS             10575..11015
                     /locus_tag="IRB70_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2756 family protein"
                     /protein_id="HBC0631569.1"
                     /translation="MKRLLILTALLPFVGFAQPINTLNNPNQPGYQIPSQQRMQTQMQ
                     TQQIQQKGMLNQQLKTQTQLQQQHLENQINNNSQRVLQSQPGERNPARQQMLPNTNGG
                     MLNGNRNPDSSLNQQHMLPERRNGDMLNQPGTPQPDIPLKTIGP"
     gene            complement(11002..11745)
                     /gene="ugpQ"
                     /locus_tag="IRB70_001647"
     CDS             complement(11002..11745)
                     /gene="ugpQ"
                     /locus_tag="IRB70_001647"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBC0631570.1"
                     /translation="MSNWPYPRIVAHRGGGKLAPENTLAAIDVGAKYGHKMIEFDAKL
                     SKDGEIFLLHDDNLERTSNGWGVAGDLNWQDLLRVDAGSWYSKAFKGEPLPLLSQVAE
                     RCRKHGMMANIEIKPTTGTGPLTGKMVALAARELWAGMTPPLLSSFEIDALDAAQQAV
                     PELPRGLLLDEWRDDWRELTARLGCVSIHLNHKLLDKARVMQLKDAGLRILVYTVNKP
                     QRAAELLRWGVDCICTDAIDVIGPNFTAQ"
     gene            complement(11742..12812)
                     /gene="ugpC"
                     /locus_tag="IRB70_001648"
     CDS             complement(11742..12812)
                     /gene="ugpC"
                     /locus_tag="IRB70_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol 3-phosphate ABC transporter ATP
                     binding protein UgpC"
                     /protein_id="HBC0631571.1"
                     /translation="MAGLKLQAVTKSWDGKTQVIKPLTLDVADGEFIVMVGPSGCGKS
                     TLLRMVAGLERVTTGDIWIDRKRVTEMEPKDRGIAMVFQNYALYPHMSVEENMAWGLK
                     IRGMGKQQIAERVKEAARILELDGLLKRRPRELSGGQRQRVAMGRAIVREPAVFLFDE
                     PLSNLDAKLRVQMRLELQQLHRRLKTTSLYVTHDQVEAMTLAQRVMVMNGGVAEQIGT
                     PVEVYEKPASLFVASFIGSPAMNLLAGRVNNEGTHFELDGCITLPLNGGYRQYAGRKM
                     TLGIRPEHIALSSQAEGGVPLVMDTLEILGADNLAHGRWGEQKLVVRLAHQERPTAGS
                     TLWLHLPENQLHLFDGETGQRV"
     gene            complement(12814..13659)
                     /gene="ugpE"
                     /locus_tag="IRB70_001649"
     CDS             complement(12814..13659)
                     /gene="ugpE"
                     /locus_tag="IRB70_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000572177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpE"
                     /protein_id="HBC0631572.1"
                     /translation="MIENRPWLTIFSHTMLILGIAVILFPLYVAFVAATLDKQEVYAA
                     PMTLIPGTHLLENIHNIWVNGVGTNSAPFWRMLLNSFVMAFSITLGKITVSMLSAFAI
                     VWFRFPLRNLFFWMIFITLMLPVEVRIFPTVEVIANLKMLDSYAGLTLPLMASATATF
                     LFRQFFMTLPDELVEAARIDGASPMRFFCDIVFPLSKTNLAALFVITFIYGWNQYLWP
                     LLIITDVDLGTTVAGIKGMIATGEGTTEWNSVMAAMLLTLIPPVVIVLVMQRAFVRGL
                     VDSEK"
     gene            complement(13656..14543)
                     /gene="ugpA"
                     /locus_tag="IRB70_001650"
     CDS             complement(13656..14543)
                     /gene="ugpA"
                     /locus_tag="IRB70_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter permease
                     UgpA"
                     /protein_id="HBC0631573.1"
                     /translation="MSSSRPVFRSRWLPYLLVAPQLIITVIFFIWPAGEALWYSLQSV
                     DPFGFSSQFVGLDNFVTLFHDSYYLDSFWTTIKFSTFVTVSGLLVSLFFAALVEYIVR
                     GSRFYQTLMLLPYAVAPAVAAVLWIFLFNPGRGLITHFLAEFGYDWNHAQNSGQAMFL
                     VVFASVWKQISYNFLFFYAALQSIPRSLIEAAAIDGAGPIRRFFKIALPLIAPVSFFL
                     LVVNLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYREGFTGLDLASSAAQSVVLMFL
                     VIVLTVVQFRYVESKVRYQ"
     gene            complement(14641..15957)
                     /gene="ugpB"
                     /locus_tag="IRB70_001651"
     CDS             complement(14641..15957)
                     /gene="ugpB"
                     /locus_tag="IRB70_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     substrate-binding protein UgpB"
                     /protein_id="HBC0631574.1"
                     /translation="MKPLRYTASALALGLALMANAQAVTTIPFWHSMEGELGKEVDSL
                     AQRFNAENPDYKIVPTYKGNYEQNLSAGIAAFRTGNAPAILQVYEVGTATMMASKAIK
                     PVYDVFKEAGIQFDESQFVPTVSGYYSDSKTGHLLSQPFNSSTPVLYYNKDAFKKAGL
                     DPEQPPKTWQDLADYAAKLKASGMKCGYASGWQGWIQLENFSAWNGLPFASKNNGFDG
                     TDAVLEFNKPEQVKHIAMLEEMNKKGDFSYVGRKDESTEKFYNGDCAMTTASSGSLAN
                     IREYAKFNYGVGMMPYDADAKDAPQNAIIGGASLWVMQGKDKETYTGVAKFLDFLAKP
                     ENAAEWHQKTGYLPITKAAYDLTREQGFYEKNPGADTATRQMLNKPPLPFTKGLRLGN
                     MPQIRVIVDEELESVWTGKKTPQQALDTAVERGNQLLRRFEKSTKS"
     gene            complement(16355..17068)
                     /gene="livF"
                     /locus_tag="IRB70_001652"
     CDS             complement(16355..17068)
                     /gene="livF"
                     /locus_tag="IRB70_001652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivF"
                     /protein_id="HBC0631575.1"
                     /translation="MEKVMLSFDKVSAHYGKIQALHEVSLHINQGEIVTLIGANGAGK
                     TTLLGTLCGDPRATSGRIVFDDKDITDWQTAKIMREAVAIVPEGRRVFSRMTVEENLA
                     MGGFFAERDQFQERIKWVYELFPRLHERRVQRAGTMSGGEQQMLAIGRALMSNPRLLL
                     LDEPSLGLAPIIIQQIFDTIEQLREQGMTIFLVEQNANQALKLADRGYVLENGHVVLS
                     DTGDALLANEAVRSAYLGG"
     gene            complement(17070..17837)
                     /gene="livG"
                     /locus_tag="IRB70_001653"
     CDS             complement(17070..17837)
                     /gene="livG"
                     /locus_tag="IRB70_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000084170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter ATP-binding protein LivG"
                     /protein_id="HBC0631576.1"
                     /translation="MSQPLLSVNGLMMRFGGLLAVNNVNLELYPQEIVSLIGPNGAGK
                     TTVFNCLTGFYKPTGGTILLRDQHLEGLPGQQIARMGVVRTFQHVRLFREMTVIENLL
                     VAQHQQLKTGLFSGLLKTPSFRRAQSEALDRAATWLERIGLLEHANRQASNLAYGDQR
                     RLEIARCMVTQPEILMLDEPAAGLNPKETKELDELIAELRNHHNTTILLIEHDMKLVM
                     GISDRIYVVNQGTPLANGTPEQIRNNPDVIRAYLGEA"
     gene            complement(17834..19111)
                     /gene="livM"
                     /locus_tag="IRB70_001654"
     CDS             complement(17834..19111)
                     /gene="livM"
                     /locus_tag="IRB70_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     permease LivM"
                     /protein_id="HBC0631577.1"
                     /translation="MKPMHIAMALLSAAMFFVLAGVFMGVQLELDGTKLVVDTASEIR
                     WQWVFIGTAVVFFFQLLRPAFQKGLKSVSGPKFILPAIDGSTVKQKLFLVALLVLAVA
                     WPFMVSRGTVDIATLTMIYIILGLGLNVVVGLSGLLVLGYGGFYAIGAYTFALLNHYY
                     GLGFWTCLPIAGLMAAAAGFLLGFPVLRLRGDYLAIVTLGFGEIVRILLLNNTEITGG
                     PNGISQIPKPTLFGLEFSRTAREGGWDTFSNFFGLKYDPSDRVIFLYLVALLLVVLSL
                     FVINRLLRMPLGRAWEALREDEIACRSLGLSPRRIKLTAFTISAAFAGFAGTLFAARQ
                     GFVSPESFTFAESAFVLAIVVLGGMGSQFAVILAAVLLVVSRELMRDFNEYSMLMLGG
                     LMVLMMIWRPQGLLPMTRPQLKLKNGAAKGEQA"
     gene            complement(19108..20034)
                     /gene="livH"
                     /locus_tag="IRB70_001655"
     CDS             complement(19108..20034)
                     /gene="livH"
                     /locus_tag="IRB70_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010436488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter permease LivH"
                     /protein_id="HBC0631578.1"
                     /translation="MSEQFLYFLQQMFNGVTLGSTYALIAIGYTMVYGIIGMINFAHG
                     EVYMIGSYVSFMIIAALMMLGIDTGWLLVAAGFVGAIVIASAYGWSIERVAYRPVRNS
                     KRLIALISAIGMSIFLQNYVSLTEGSRDVALPSLFNGQWVVGHSENFSASITTMQAVI
                     WIVTFLAMLALTIFIRYSRMGRACRACAEDLKMASLLGINTDRVIALTFVIGAAMAAV
                     AGVLLGQFYGVINPYIGFMAGMKAFTAAVLGGIGSIPGAMIGGLILGIAEALSSAYLS
                     TEYKDVVSFALLILVLLVMPTGILGRPEVEKV"
     gene            complement(20082..21191)
                     /gene="livK"
                     /locus_tag="IRB70_001656"
     CDS             complement(20082..21191)
                     /gene="livK"
                     /locus_tag="IRB70_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="high-affinity branched-chain amino acid ABC
                     transporter substrate-binding protein LivK"
                     /protein_id="HBC0631579.1"
                     /translation="MKRNAKTIIAGMIALTISHTAMADDIKVAVVGAMSGPIAQWGDM
                     EFNGARQAIKDINAKGGIKGDKLVGVEYDDACDPKQAVAVANKIVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMISPGATNPELTQRGYQYIMRTAGLDSSQGPTAAKYILETVK
                     PQRIAIIHDKQQYGEGLARSVQDGLKAANANVVFFDGITAGEKDFSALIARLKKENID
                     FVYYGGYYPEMGQMLRQARSVGLKTQFMGPEGVGNASLSNIAGDAAEGMLVTMPKRYD
                     QDPANQDIVDALKADKKDPSGPYVWITYAAVQSLATALERTGSDEPLALVKDLKANGA
                     NTVIGPLNWDEKGDLKGFDFGVFQWHADGSSTAAK"
     gene            21615..21998
                     /gene="panM"
                     /locus_tag="IRB70_001657"
     CDS             21615..21998
                     /gene="panM"
                     /locus_tag="IRB70_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase autocleavage activator
                     PanM"
                     /protein_id="HBC0631580.1"
                     /translation="MKLTIIRLENFSDQDRIDLQKIWPEYSPSSLQVDDNHRIYAARF
                     NERLLAAVRVTLSGTEGALDSLRVREVTRRRGVGQYLLEEVLRTNPGVSCWWMADAGV
                     EDRGVMTAFMRALGFTAQQGGWEKR"
     gene            complement(22186..23289)
                     /gene="livJ"
                     /locus_tag="IRB70_001658"
     CDS             complement(22186..23289)
                     /gene="livJ"
                     /locus_tag="IRB70_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched chain amino acid ABC transporter
                     substrate-binding protein LivJ"
                     /protein_id="HBC0631581.1"
                     /translation="MNIKGKALLAGCIALAFSNMALAEDIKVAVVGAMSGPVAQYGDQ
                     EFTGAEQAVADINAKGGIKGNKLQIVKYDDACDPKQAVAVANKVVNDGIKYVIGHLCS
                     SSTQPASDIYEDEGILMITPAATAPELTARGYQLILRTTGLDSDQGPTAAKYILEKVK
                     PQRIAIVHDKQQYGEGLARAVQDGLKKGNANVVFFDGITAGEKDFSTLVARLKKENID
                     FVYYGGYHPEMGQILRQARAAGLKTQFMGPEGVANVSLSNIAGESAEGLLVTKPKNYD
                     QVPANKPIVDAIKAKKQDPSGAFVWTTYAALQSLQAGLNQSDDPAEIAKYLKANSVDT
                     VMGPLSWDEKGDLKGFEFGVFDWHANGTATDAK"
     gene            complement(23561..24415)
                     /gene="rpoH"
                     /locus_tag="IRB70_001659"
     CDS             complement(23561..24415)
                     /gene="rpoH"
                     /locus_tag="IRB70_001659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoH"
                     /protein_id="HBC0631582.1"
                     /translation="MTDKMQSLALAPVGNLDSYIRAANAWPMLSADEERALAEKLHYH
                     GDLEAAKTLILSHLRFVVHIARNYAGYGLPQADLIQEGNIGLMKAVRRFNPEVGVRLV
                     SFAVHWIKAEIHEYVLRNWRIVKVATTKAQRKLFFNLRKTKQRLGWFNQDEVEMVARE
                     LGVTSKDVREMESRMAAQDMTFDLSSDDDSDSQPMAPVLYLQDKSSNFADGIEDDNWE
                     EQAANRLTDAMQGLDERSQDIIRARWLDEDNKSTLQELADRYGVSAERVRQLEKNAMK
                     KLRAAIEA"
     gene            complement(24660..25718)
                     /gene="ftsX"
                     /locus_tag="IRB70_001660"
     CDS             complement(24660..25718)
                     /gene="ftsX"
                     /locus_tag="IRB70_001660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsX"
                     /protein_id="HBC0631583.1"
                     /translation="MNKRDAINHIRQFGGRLDRFRKSVGGSGDGGRNAPKRAKSSPKP
                     VNRKTNVFNEQVRYAFHGALQDLKSKPFATFLTVMVIAISLTLPSVCYMVYKNVNQAA
                     TQYYPSPQITVYLQKTLDDDAAAGVVAQLQAEQGVEKVNYLSREDALGEFRNWSGFGG
                     ALDMLEENPLPAVAVVIPKLDFQGTESLNTLRDRITQINGIDEVRMDDSWFARLAALT
                     GLVGRVSAMIGVLMVAAVFLVIGNSVRLSIFARRDSINVQKLIGATDGFILRPFLYGG
                     ALLGFSGALLSLILSEILVLRLSSAVAEVAQVFGTKFDINGLSFDECLLLLLVCSMIG
                     WVAAWLATVQHLRHFTPE"
     gene            complement(25711..26379)
                     /gene="ftsE"
                     /locus_tag="IRB70_001661"
     CDS             complement(25711..26379)
                     /gene="ftsE"
                     /locus_tag="IRB70_001661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBC0631584.1"
                     /translation="MIRFEHVSKAYLGGRQALQGVTFHMQPGEMAFLTGHSGAGKSTL
                     LKLICGIERPSAGKIWFSGHDITRLKNREVPFLRRQIGMIFQDHHLLMDRTVYDNVAI
                     PLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPAVLL
                     ADEPTGNLDDALSEGILRLFEEFNRVGVTVLMATHDINLISRRSYRMLTLSDGHLHGG
                     VGHE"
     gene            complement(26382..27869)
                     /gene="ftsY"
                     /locus_tag="IRB70_001662"
     CDS             complement(26382..27869)
                     /gene="ftsY"
                     /locus_tag="IRB70_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBC0631585.1"
                     /translation="MAKEKKRGFFSWLGFGQKEQTPEKETEVQNEQPVVEEIVQAQEP
                     VKASEQAVEEQPQAHTEAEAETFAADVVEVTEQVAESEKAQPEAEVVAQPELVAEETP
                     EPVAIEREELPLPEDVNAEEVSPEEWQAEAETVEIVEAAEEEAAKEEITDEELEAQAL
                     AAEEAVIVVPPAEEEQPVEEIAQEQEKPTKEGFFARLKRSLLKTKENLGSGFISLFRG
                     KKIDDDLFEELEEQLLIADVGVETTRKIITNLTEGASRKQLRDAEALYGLLKEEMGEI
                     LAKVDEPLNVEGKTPFVILMVGVNGVGKTTTIGKLARQFEQQGKSVMLAAGDTFRAAA
                     VEQLQVWGQRNNIPVIAQHTGADSASVIFDAIQAAKARNIDVLIADTAGRLQNKSHLM
                     EELKKIVRVMKKLDVEAPHEVMLTIDASTGQNAVSQAKLFHEAVGLTGITLTKLDGTA
                     KGGVIFSVADQFGIPIRYIGVGERIEDLRPFKADDFIEALFARED"
     gene            28019..28615
                     /gene="rsmD"
                     /locus_tag="IRB70_001663"
     CDS             28019..28615
                     /gene="rsmD"
                     /locus_tag="IRB70_001663"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase"
                     /protein_id="HBC0631586.1"
                     /translation="MKKPNHSGSGQIRIIGGQWRGRKLPVPDSPGLRPTTDRVRETLF
                     NWLAPVIVDAQCLDCFAGSGALGLEALSRYAAGATLIEMDRAVSQQLIKNLATLKAGN
                     ARVVNSNAMSFLAQKGTPHNIVFVDPPFRRGLLEETINLLEDNGWLADEALIYVESEV
                     ENGLPTVPANWSLHREKVAGQVAYRLYQREAQGESDVD"
     gene            28605..28874
                     /locus_tag="IRB70_001664"
     CDS             28605..28874
                     /locus_tag="IRB70_001664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1145 family protein"
                     /protein_id="HBC0631587.1"
                     /translation="MLINIGRLLMLCVWGFLILNLVHPFPRPLNIFVNVALIFTVLMH
                     GMQLALLKSTLPKDGPQMTTAEKVRIFLFGVFELLVWQKKFKVKK"
     gene            complement(28877..29236)
                     /locus_tag="IRB70_001665"
     CDS             complement(28877..29236)
                     /locus_tag="IRB70_001665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2500 domain-containing protein"
                     /protein_id="HBC0631588.1"
                     /translation="MSKPPLFFIVIIGLIIVAASFRFMQQRREKADNDMAPLQQKLVV
                     VSNKREKPINDRRSRQQEVTPAGTSMRYEASFKPQSGGMEQTFRLDAQQYHALTVGDK
                     GTLSYKGTRFVSFVGEQ"
     gene            29377..30003
                     /locus_tag="IRB70_001666"
     CDS             29377..30003
                     /locus_tag="IRB70_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysoplasmalogenase"
                     /protein_id="HBC0631589.1"
                     /translation="MLWSFIAVCLSAWLSVDASYRGPTWQRWVFKPLTLLLLLLLAWQ
                     APMFDAISYLVLAGLCASLLGDALTLLPRQRLMYAIGAFFLSHLLYTIYFASQMTLSF
                     FWPLPLVLLVLGALLLAIIWTRLEEYRWPICTFIGMTLVMVWLAGELWFFRPTAPALS
                     AFVGASLLFISNFVWLGSHYRRRFRADNAIAAACYFAGHFLIVRSLYL"
     gene            30077..32275
                     /gene="zntA"
                     /locus_tag="IRB70_001667"
     CDS             30077..32275
                     /gene="zntA"
                     /locus_tag="IRB70_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(II)/Cd(II)/Pb(II) translocating P-type ATPase
                     ZntA"
                     /protein_id="HBC0631590.1"
                     /translation="MSTPDNHGKKAPQFAAFKPLTTVQNANDCCCDGACSSTPTLSEN
                     VSGTRYSWKVSGMDCAACARKVENAVRQLAGVNQVQVLFATEKLVVDADNDIRAQVES
                     AVQKAGYSLRDEQAADEQQASRLKENLPLITLIVMMAISWGLEQFNHPFGQLAFIATT
                     LVGLYPIARQALRLIKSGSYFAIETLMSIAAIGALFIGATAEAAMVLLLFLIGERLEG
                     WAASRARQGVSALMALKPETATRLSNGEREEVAINSLRPGDVIEVAAGGRLPADGKLL
                     SPFASFDESALTGESIPVERATGDKVPAGATSVDRLVTLEVLSEPGASAIDRILKLIE
                     EAEERRAPIERFIDRFSRIYTPAIMAVALLVTLVPPLLFAASWQEWIYKGLTLLLIGC
                     PCALVISTPAAITSGLAAAARRGALIKGGAALEQLGRVTQVAFDKTGTLTVGKPRVTA
                     IHPATGISESELLTLAAAVEQGATHPLAQAIVREAQIAELAIPTAQSQRALVGSGIEA
                     QVNGERVLICAAGKHPADAFAGLINELESAGQTVVLVVRNDDVLGIIALQDTLRADAA
                     TAISELNALGVKGVILTGDNPRAAAAIAGELGLEFKAGLLPEDKVKAVTELNQHAPLA
                     MVGDGINDAPAMKAAAIGIAMGSGTDVALETADAALTHNHLRGLVQMIELARATHANI
                     RQNITIALGLKGVFLVTTLLGMTGLWLAVLADTGATVLVTANALRLLRRK"
     gene            complement(32377..32622)
                     /gene="tusA"
                     /locus_tag="IRB70_001668"
     CDS             complement(32377..32622)
                     /gene="tusA"
                     /locus_tag="IRB70_001668"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA"
                     /protein_id="HBC0631591.1"
                     /translation="MTDLFSSPDHTLDALGLRCPEPVMMVRKTVRNMQPGETLLIIAD
                     DPATTRDIPGFCTFMEHELVAKETDGLPYRYLIRKGG"
     gene            32843..33508
                     /locus_tag="IRB70_001669"
     CDS             32843..33508
                     /locus_tag="IRB70_001669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-cyano-7-deazaguanine/7-aminomethyl-7-
                     deazaguanine transporter"
                     /protein_id="HBC0631592.1"
                     /translation="MNVFSQTQRYKALFWLSLFHLLVITSSNYLVQLPVSIFGFHTTW
                     GAFSFPFIFLATDLTVRIFGAPLARRIIFAVMIPALLISYVISSLFYMGSWQGFGALA
                     HFNLFVARIATASFMAYALGQILDVHVFNRLRQSRRWWLAPTASTLFGNVSDTLAFFF
                     IAFWRSPDAFMAEHWMEIALVDYCFKVLISIVFFLPMYGVLLNMLLKRLADKSEINAL
                     QAS"
     gene            33581..34138
                     /gene="dcrB"
                     /locus_tag="IRB70_001670"
     CDS             33581..34138
                     /gene="dcrB"
                     /locus_tag="IRB70_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417929.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage sensitivity protein DcrB"
                     /protein_id="HBC0631593.1"
                     /translation="MRNLVKYVGIGLLVMGLAACDDKDTNATAQGSVAESNATGNPVN
                     LLDGKLSFSLPADMTDQSGKLGTQANNMHVWSDATGQKAVIVIMGDDPKEDLAVLAKR
                     LEDQQRSRDPQLQVVTNKAIELKGHKMQQLDSIISAKGQTAYSSVILGNVGNQLLTMQ
                     ITLPADDQQKAQTTAENIINTLVIQ"
     gene            complement(34142..35392)
                     /locus_tag="IRB70_001671"
     CDS             complement(34142..35392)
                     /locus_tag="IRB70_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312349.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0631594.1"
                     /translation="MKHCCKNVVILMPEPVAEPALNGLRLNLRIVSIVMFNFASYLTI
                     GLPLAVLPGYVHDVMGFSAFWAGLVISLQYFATLLSRPHAGRYADLLGPKKIVVFGLC
                     GCFLSGLGYLTAGLTASLPVISLLLLCLGRVILGIGQSFAGTGSTLWGVGVVGSLHIG
                     RVISWNGIVTYGAMAMGAPLGVVFYHWGGLQALALIIMGVALVAILLAIPRPTVKASK
                     GKPLPFRAVLGRVWLYGMALALASAGFGVIATFITLFYDAKGWDGAAFALTLFSCAFV
                     GTRLLFPNGINRIGGLNVAMICFSVEIIGLLLVGVATMPWMAKIGVLLAGAGFSLVFP
                     ALGVVAVKAVPQQNQGAALATYTVFMDLSLGVTGPLAGLVMSWAGVPVIYLAAAGLVA
                     IALLLTWRLKKRPPVEVPEAISSS"
     gene            35491..36540
                     /locus_tag="IRB70_001672"
     CDS             35491..36540
                     /locus_tag="IRB70_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBC0631595.1"
                     /translation="METPQPDKTGMHILLKLASLVVILAGIHAAADIIVQLLLALFFA
                     IVLNPLVTWFIRRGVQRPVAITIVVVVMLIALTALVGVLAASFNEFISMLPKFNKELT
                     RKLFKLQEMLPFLNLHMSPERILQRMDSEKMVTFTTALMTGLSGAMASVLLLVMTVVF
                     MLFEVRHVPYKMRFALNNPQIHIAGLHRALKGVSHYLALKTLLSLWTGVIVWLGLALM
                     GVQFALMWAVLAFLLNYVPNIGAVISAVPPMIQVLLFNGVYECILVGALFLVVHMVIG
                     NILEPRMMGHRLGMSTMVVFLSLLIWGWLLGPVGMLLSVPLTSVCKIWMETTKGGSKL
                     AILLGPGRPKSRLPG"
     gene            36595..37182
                     /gene="acpT"
                     /locus_tag="IRB70_001673"
     CDS             36595..37182
                     /gene="acpT"
                     /locus_tag="IRB70_001673"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase AcpT"
                     /protein_id="HBC0631596.1"
                     /translation="MYRIVLGKVSTLSAAPLPPGLREQAPQGPRRERWLAGRALLSHT
                     LSPLPEIIYGEQGKPAFAPETPLWFNLSHSGDDIALLLSDEGEVGCDIEVIRPRANWR
                     WLANAVFSLGEHAEMDAVHPDQQLEMFWRIWTRKEAIVKQRGGSAWQIVSVDSTYNSS
                     LSVSHCQLENLSLAICTPTPFTLTADSVQWIDSVN"
     gene            37293..38867
                     /gene="nikA"
                     /locus_tag="IRB70_001674"
     CDS             37293..38867
                     /gene="nikA"
                     /locus_tag="IRB70_001674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter, nickel/metallophore
                     periplasmic binding protein"
                     /protein_id="HBC0631597.1"
                     /translation="MFSTLRRTLFALLACASFIVHAAAPDEITTAWPVNVGPLNPHLY
                     TPNQMFAQSMVYEPLVKYQADGSVIPWLAKSWTHSEDGKTWTFTLRDDVKFSNGEPFD
                     AEAAAENFRAVLDNRQRHAWLELANQIVDVKALSKTELQITLKSAYYPFLQELALPRP
                     FRFIAPSQFKNHETMNGIKAPIGTGPWVLQESKLNQYDVFVRNENYWGEKPAIKKITF
                     NVIPDPTTRAVAFETGDIDLLYGNEGLLPLDTFARFSQNSAYHTQLSQPIETVMLALN
                     TAKAPTNELAVREALNYAVNKKSLIDNALYGTQQVADTLFAPSVPYANLGLKPRQYDP
                     QKAKALLEQAGWTLPAGKDIREKNGQPLRIELSFIGTDALSKSMAEIIQADMRQIGAD
                     VTLIGEEESSIYARQRDGRFGMIFHRTWGAPYDPHAFLSSMRVPSHADFQAQQGLADK
                     PLIDKEIGEVLATHDETQRQALYRDILTRLHNEAVYLPISYISMMVVSKPELGNIPYA
                     PIATEIPFEQIKPVKP"
     gene            38867..39811
                     /gene="nikB"
                     /locus_tag="IRB70_001675"
     CDS             38867..39811
                     /gene="nikB"
                     /locus_tag="IRB70_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikB"
                     /protein_id="HBC0631598.1"
                     /translation="MLRYVLRRFLLLIPMVLAASVIIFLMLRLGTGDPALDYLRLSNL
                     PPTPEMLASTRTMLGLDQPLYVQYGTWLWKALHLDFGISFASQRPVLDDMLTFLPATL
                     ELAGAALVLILLTSVPLGIWAARHRDRLPDFAVRFIAFLGVSMPNFWLAFLLVMAFSV
                     YLQWLPAMGYGGWQHIILPAVSIAFMSLAINARLLRASMLDVAGQRHVTWARLRGLND
                     KQTERRHILRNASLPMITAVGMHIGELIGGTMIIENIFAWPGVGRYAVSAIFNRDYPV
                     IQCFTLMMVVVFVVCNLIVDLLNAALDPRIRRHEGAHA"
     gene            39808..40641
                     /gene="nikC"
                     /locus_tag="IRB70_001676"
     CDS             39808..40641
                     /gene="nikC"
                     /locus_tag="IRB70_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel ABC transporter permease subunit NikC"
                     /protein_id="HBC0631599.1"
                     /translation="MNFFLSSRWSVRLALIIIALLALIALTSQWWLPYDPQAIDLPSR
                     LLSPDAQHWLGTDHLGRDIFSRLMAATRVSLGSVMACLLLVLTLGLVIGGSAGLIGGR
                     VDQATMRVADMFMTFPTSILSFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSLVISL
                     RQREFVLASRLSGAGHVRVFVDHLAGAVIPSLLVLATLDIGHMMLHVAGMSFLGLGVT
                     APTAEWGVMINDARQYIWTQPLQMFWPGLALFISVMAFNLVGDALRDHLDPHLVTEHA
                     H"
     gene            40641..41405
                     /gene="nikD"
                     /locus_tag="IRB70_001677"
     CDS             40641..41405
                     /gene="nikD"
                     /locus_tag="IRB70_001677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikD"
                     /protein_id="HBC0631600.1"
                     /translation="MPQQIELRNIALQAAQPLVHGVSLTLKRGRVLALVGGSGSGKSL
                     TCAATLGILPAGVRQTAGEILADGKPVSPCALRGIKIATIMQNPRSAFNPLHTMHTHA
                     RETCLALGKPADDATLTAAIEAVGLENAARVLKLYPFEMSGGMLQRMMIAMAVLCESP
                     FIIADEPTTDLDVVAQARILDLLESIMQKQAPGMLLVTHDMGVVARLADDVAVMSHGK
                     IVEQGDVETLFNAPKHAVTRSLVSAHLALYGMELAS"
     gene            41402..42208
                     /gene="nikE"
                     /locus_tag="IRB70_001678"
     CDS             41402..42208
                     /gene="nikE"
                     /locus_tag="IRB70_001678"
                     /EC_number="7.2.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel import ATP-binding protein NikE"
                     /protein_id="HBC0631601.1"
                     /translation="MTLLNVSDLSHHYAHGGFSGKHQHQAVLNNVSLTLKSGETVALL
                     GRSGCGKSTLARLLVGLESPSQGNISWRGEPLAKLNRAQRKAFRRDIQMVFQDSISAV
                     NPRKTVREILREPMRHLLSLKKAEQLARASEMLKAVDLDDSVLDKRPPQLSGGQLQRV
                     CLARALAVEPKLLILDEAVSNLDLVLQAGVIRLLKKLQQQFGTACLFITHDLRLVERF
                     CQRVMVMDNGQIVETQVVGDKLTFSSDAGRVLQNAVLPAYPVRRRATEKV"
     gene            42213..42614
                     /gene="nikR"
                     /locus_tag="IRB70_001679"
     CDS             42213..42614
                     /gene="nikR"
                     /locus_tag="IRB70_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel-responsive transcriptional regulator
                     NikR"
                     /protein_id="HBC0631602.1"
                     /translation="MQRVTITLDDDLLETLDSLSQRRGYNNRSEAIRDILRSALAQEA
                     TQQHGTQGFAVLSYVYEHEKRDLASRIVSTQHHHHDLSVATLHVHINHDDCLEIAVLK
                     GDMGDVQHFADDVIAQRGVRHGHLQCLPKED"
     gene            complement(42734..43093)
                     /locus_tag="IRB70_001680"
     CDS             complement(42734..43093)
                     /locus_tag="IRB70_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBC0631603.1"
                     /translation="MIKLKTPNSMEIAGQPAVITYVPELNAFRGKFLGLSGYCDFVSD
                     SIQGLQKEGELSLREYLEDCKAAGIEPYARTEKIKTFTLRYPESLSERLNNAAAQQQV
                     SVNTYIIETLNERLNHL"
     gene            complement(43090..43365)
                     /locus_tag="IRB70_001681"
                     /pseudo
     CDS             complement(43090..43365)
                     /locus_tag="IRB70_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312384.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
     gene            complement(43438..44562)
                     /locus_tag="IRB70_001682"
     CDS             complement(43438..44562)
                     /locus_tag="IRB70_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709253.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0631604.1"
                     /translation="MRHLRNIFNLGIKELRSLLGDKAMLTLIVFSFTVSVYSSATVTP
                     GSLNLAPIAIADMDQSQLSNRIVNSFYRPWFLPPEMITADEMDAGLDAGRYTFAINIP
                     PNFQRDVLAGRQPDIQVNVDATRMSQAFTGNGYIQNIINGEVNSFVARYRDNSEPLVS
                     LETRMRFNPNLDPAWFGGVMAIINNITMLAIVLTGSALIREREHGTVEHLLVMPITPF
                     EIMMAKVWSMGLVVLVVSGLSLVLMVKGVLGVPIEGSIPLFMLGVALSLFATTSIGIF
                     MGTIARSMPQLGLLVILVLLPLQMLSGGSTPRESMPQMVQDIMLTMPTTHFVSLAQAI
                     LYRGAGFEIVWPQFLTLMAIGGAFFTIALLRFRKTIGTMA"
     gene            complement(44562..47297)
                     /gene="rbbA"
                     /locus_tag="IRB70_001683"
     CDS             complement(44562..47297)
                     /gene="rbbA"
                     /locus_tag="IRB70_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated ATPase/putative transporter
                     RbbA"
                     /protein_id="HBC0631605.1"
                     /translation="MTHLELVPVPPVAQLAGVSQHYGKTVALNNITLDIPARCMVGLI
                     GPDGVGKSSLLSLISGARVIEQGNVIVLGGDMRDPKHRRDVCPRIAWMPQGLGKNLYH
                     TLSVYENVDFFARLFGHDKAEREVRINELLTSTGLAPFRDRPAGKLSGGMKQKLGLCC
                     ALIHDPELLILDEPTTGVDPLSRAQFWDLIDSIRQRQSNMSVLVATAYMEEAERFDWL
                     VAMNAGEVLATGSAEELRQQTQSATLEEAFINLLPQAQRQAHQAVVIPPYQPENAEIA
                     IEARDLTMRFGSFVAVDHVNFRIPRGEIFGFLGSNGCGKSTTMKMLTGLLPASEGEAW
                     LFGQPVDPKDIDTRRRVGYMSQAFSLYNELTVRQNLELHARLFHIPEAEIPARVAEMS
                     ERFKLNDVEDVLPESLPLGIRQRLSLAVAVIHRPEMLILDEPTSGVDPVARDMFWQLM
                     VDLSRQDKVTIFISTHFMNEAERCDRISLMHAGKVLASGTPQELVEKRGAASLEEAFI
                     AYLQEAAGQSNEAEAPPVVHDTTHAPRQGFSLRRLFSYSRREALELRRDPVRSTLALM
                     GTVILMLIMGYGISMDVENLRFAVLDRDQTVSSQAWTLNLSGSRYFIEQPPLTSYDEL
                     DRRMRAGDITVAIEIPPNFGRDIARGTPVELGVWIDGAMPSRAETVKGYVQAMHQSWL
                     QDVASRQSTPASQSGLMNIETRYRYNPDVKSLPAIVPAVIPLLLMMIPSMLSALSVVR
                     EKELGSIINLYVTPTTRSEFLLGKQLPYIALGMLNFFLLCGLSVFVFGVPHKGSFLTL
                     TLAALLYIIIATGMGLLISTFMKSQIAAIFGTAIITLIPATQFSGMIDPVASLEGPGR
                     WIGEVYPTSHFLTIARGTFSKALDLTDLWQLFIPLLIAIPLVVGLSILLLKKQEG"
     gene            complement(47294..48361)
                     /locus_tag="IRB70_001684"
     CDS             complement(47294..48361)
                     /locus_tag="IRB70_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBC0631606.1"
                     /translation="MDKSKRHLAWWVVGLLAVAAIVAWWLLRPAGVPEGFAVSNGRIE
                     ATEVDIASKIAGRIDTILVKEGQFVREGEVLAKMDTRVLQEQRMEAIAQIKEAQSAVA
                     AAQALLEQRQSETRAAQSLVNQRQAELDSVAKRHTRSRSLAQRGAISAQQLDDDRAAA
                     ESARAALESAKAQVSASKAAIEAARTNIIQAQTRVEAAQATERRIAADIDDSELKAPR
                     DGRVQYRVAEPGEVLAAGGRVLNMVDLSDVYMTFFLPTEQAGTLKLGGEARLILDAAP
                     DLRIPATISFVASVAQFTPKTVETSDERLKLMFRVKARIPPELLQQHLEYVKTGLPGV
                     AWVRVNEELPWPEDLAVRLPQ"
     gene            complement(48727..>49576)
                     /locus_tag="IRB70_001685"
     CDS             complement(48727..>49576)
                     /locus_tag="IRB70_001685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
                     /protein_id="HBC0631607.1"
                     /translation="NTIISILNRRDVVLESIQPYLVINKGAVTPCTFLGDQTGDRFSN
                     ICGDQFIIDLLKRIMSINENFHVLAGNHETNCNGNYMQNFTRMKPLDEDTYDGIKDYP
                     VCFYDPKYKIMANHHGITFDDQRKRYIIGPITVSIDEMTNALDPVELAAIINKKHHTI
                     INGKKFKTSRAISCRSFNRYFSVSTDYRPKLEALLACSQMLGINQVVAHNGNGGRERI
                     GETGTVLGLNARDSKHAGRMFSMHNCQINPGAGPEITTPWKSYQHEKNKNGLMPLIRR
                     RTMLQL"
BASE COUNT        11654 a        13743 c        12587 g        11592 t
ORIGIN      
        1 agacaataac cctggtaaat gcttcaataa tattgaaaaa ggaagagtat gagtattcaa
       61 cattttcgtg tcgcccttat tccctttttt gcggcatttt gccttcctgt ttttgctcac
      121 ccagaaacgc tggtgaaagt aaaagatgct gaagatcagt tgggtgcacg agtgggttac
      181 atcgaactgg atctcaacag cggtaagatc cttgagagtt ttcgccccga agaacgtttt
      241 ccaatgatga gcacttttaa agttctgcta tgtggtgcgg tattatcccg tgttgacgcc
      301 gggcaagagc aactcggtcg ccgcatacac tattctcaga atgacttggt tgagtactca
      361 ccagtcacag aaaagcatct tacggatggc atgacagtaa gagaattatg cagtgctgcc
      421 ataaccatga gtgataacac tgctgccaac ttacttctga caacgatcgg aggaccgaag
      481 gagctaaccg cttttttgca caacatgggg gatcatgtaa ctcgccttga tcgttgggaa
      541 ccggagctga atgaagccat accaaacgac gagcgtgaca ccacgatgcc tgcagcaatg
      601 gcaacaacgt tgcgcaaact attaactggc gaactactta ctctagcttc ccggcaacaa
      661 ttaatagact ggatggaggc ggataaagtt gcaggaccac ttctgcgctc ggcccttccg
      721 gctggctggt ttattgctga taaatctgga gccggtgagc gtgggtctcg cggtatcatt
      781 gcagcactgg ggccagatgg taagccctcc cgtatcgtag ttatctacac gacggggagt
      841 caggcaacta tggatgaacg aaatagacag atcgctgaga taggtgcctc actgattaag
      901 cattggtaac tgtcagacca agtttactca tatatacttt agattgattt aaaacttcat
      961 ttttaattta aaaggatcta ggtgaagatc ctttttgata atctcatgac caaaatccct
     1021 taacgtgagt tttcgttcca ctgagcgtca gaccccttga tcgaggtggc cagccgcagg
     1081 atttcgttaa taaataaatt tgccgcatgg agtaagccgc tatcaatgtc gggcgacaat
     1141 aacggatgct gaagacaact gctacattta ccacaacgtt cggcacttgg ctcatcgagt
     1201 gcacggcgca gaaattgcat tttgcactcc ttggtcgtga tatagctttc aacgtctgcc
     1261 agttcacttt ttctctgatt catcaaatgg ttaattcgtt catgatcagg agaaaaactg
     1321 acgatagttc tgcgccataa tttctcggta tacaccacag gcgatggatt ttccgctacc
     1381 aataatttca gtgctttttc tatttgccca taacgaagat tcgtccgttg ttcaatgcct
     1441 cgtagggtaa gaccgtcatt ctcgctaagt actttgagta tttcatgaat ttgcgcctcc
     1501 gcaggaaagg cgctttcacg gaagaattga tgaatagcgc ggtcttcacc accacaaagc
     1561 aatatgccaa ctgcggaatc tatagcacgc ccggcacgcc ccacctgttg gtagtaaccg
     1621 acaatagacc ccggcatctg ataatgaatg acgaaaccta aatcaggttt atcaaacccc
     1681 atacctaatg ccgtcgtcgc gaccagcact ttgattttat ttgccagcag tgcctgctcc
     1741 agatattccc tggcagtatt agaatcttcc gcgccttcac aagtcacgcc gctgtagtaa
     1801 gcaaatgcac tgataccatt tttccttaac cactcggcga caagttcagc atcgcgagtc
     1861 gtcagggtat aaacaattcc cgatttggaa aactgaggga taaccgttgc taaccatgcc
     1921 agacgggatg actgttctcc taagactaag gcatcaagcg ccaaactttc gcgagccagc
     1981 gttccacgct gaatcacaat gtcacccaat tgctgacgga tatcctcaac aacacggtta
     2041 ttcgctgtcg cggttgtacc cagaacaggg gtattcgcag gcagttggcg caaaatatct
     2101 aatatacgtc ggtaatccgg gcgaaaatcg tggccccaat cagagatgca gtgcgcctcg
     2161 tcgaccacaa gcaagccaat acgatcggct ataggatata aaaccgtttc gataaagtcc
     2221 tggtttgcca aacgttccgg ggaaaccagc aagcaatcga cctcaccttg cagcaactta
     2281 tcgctaatgc gctgccattc ttccctgttt gtagaattca acgtttcagc cgtaatacct
     2341 aaccgttcag cggcggcaac ctggttacgc atcagggcaa gcaaaggaga gatgataatt
     2401 gtcgggccag cgccgcgatc gcggaagatt ttactggcga tgaagtacac ggcacttttc
     2461 ccccagccgg tgcgctgtac aaccagcagt tttcgccgct gattaaccac tgcatctatg
     2521 gcttcccatt gcccttccct gaaagtagcg gtggtatttc ctaacatccg ctgtaaaagc
     2581 aattcagctc cgtgcttttc catctttatc tcctgcgatc tttaggcagt gattagaacg
     2641 gattattagc aggtaaattt gcgagagaga tcaaaaagat gaagagagga gataagagaa
     2701 atgaattact gcgagcaagc tcgcagtaat ttgtcgcagt aattaactca acagctggaa
     2761 cgcaatcatc ccaacgatgg caccaacagt gccgagtatg gtttccatca tggtccaggt
     2821 tttcagcgtt tcggcttcgg tcgcgccggt aaatttaccg aacaaccaga aaccggcgtc
     2881 gttaacgtgg ctgacaacaa tcgaaccacc ggcgatacaa atcgacagcg ccgccatttg
     2941 cgcaccggag tagttcagtt gttcaataac cggcatcacc agtcccaccg ccgttaaaca
     3001 ggcaacggtg gcagaaccct gaatgatgcg cactgcagct gccagcacga agcaggtgat
     3061 ggcaatcggc aggcccatgc cggttaacgc ttcgcccagt gccggaccta cgcctgagtc
     3121 aaccagcacc tgtttgaaca cgccgcccgc accaatcacc agcagaatga tccccgccgg
     3181 ttgcagcgcg tgaccgcaaa tctccatcac tttgtctttt ggcatgccct gacgcattgc
     3241 cagaccgtaa atcgccacca gacaagcaac cagaatcgcg gtaaacggat ggccgataaa
     3301 ctcgaaccat tcgtaagcgg tagagccttc tggcacaaaa cgcgcggcaa tggttttcag
     3361 ccccaccagc accagtggca acaggatcag cgacaggctg aatccgaagg acggcatttt
     3421 gccttcgccg agatgtggtt cgctgatgtc gtcaggaata tgcagctcca cgtagcggct
     3481 gatgaaatta ccccacagcg gcccggcaat aatcattccc ggaattgccg cacacaggcc
     3541 aatcaggatc atccagccaa agtcggcgtt catctgcgat gccagcagca ttggcgctgg
     3601 tccaggcacc aggaacgcag ccgctgccgc cacgcctgcg aataatggga ttaccagctt
     3661 caccaggttc gtaccggtgt ggcgcgccat tgagaaagca acgctaatca gcagaacaat
     3721 cgccacttca aagaacagcg gtagcgcaca gaccagcccc gcaagaccga tggcataatg
     3781 cgcgcgactg tgaccgaagg atttgagcat tttgacggca atctgatcga ctgcgccggt
     3841 ttcatgtaag atcttgccaa acatggctcc cagggcgaca accaccgcca gaaagccgag
     3901 ggtgcctccc atcccttttt ccatcgtcgc tgcgatttta tcgagcggca taccggaaaa
     3961 aaggccagcc cccatggaca ccaccatcaa agccaggaaa gcgtgcatac gcgccttcat
     4021 gactaaaaac agcagcagta aaacagaccc tactgctgtt aaaacaagcg ttaatgtagt
     4081 cactacttat ttgccttttt taataacctc aatggtgctt gccacaacac cttccagcgg
     4141 ttgatcgata tccaccacca gtacatcggt ttcgtccgca cccggctcct gcagcgtttc
     4201 aaactgcgtc accaacattt gggttttaaa gaaatggcct ttgcgcgctt tcaggcggct
     4261 ttcaatcaca tcaaaatcgc ctttcaggta gatgaaagag agattcggat tacccgcgcg
     4321 tagcaagtcg cgatagtgtt ttttcagtgc agaacagacg atcagcgaca ctttattggt
     4381 gcgctgcata gcaaacgcgg cgtcgttcag cgcctgcaac cacggtttgc gatcgtcgtc
     4441 attcagcggt tcaccagacg ccattttttc gatattgcgc cgtggatgga ggaaatcgcc
     4501 atcaagaaac gcggcatgaa gttgatgcgc cacttcactg gcgaccgcag atttgccgct
     4561 gcccgatacg cccatcaaga cgtaaatgtg gtgatcatgg ttagtcgtgc tcaaagtggt
     4621 gcccccacaa tacaagaatt aaaaatgtta cgggtaactg ttatcggtaa cattgtccgg
     4681 ccggacaata tcagaagcaa tatccatccg tgccttaagt gtataagtgt gagctacttc
     4741 aaatttgtgg gcttaaatag atccgcccgg tgacaaggtg aaacctaaat ctaacatttt
     4801 cggtgtcaca gattcgccac gaatacgcgc cagcaggcgt tcagcgccaa tactgcccat
     4861 ccgctcacgc ggcgtcagta cgctcgccaa ccgtggttcc atcacctgac caatgtcatg
     4921 accatggaaa ccggcaatcg ccatatcgtc aggaactttt aaccccagac gctgacattc
     4981 aaacgccgcg ccgaccgcca gatcatcatt agtacagaac acgccatcca gctgcggata
     5041 ttcccgccgt gcctggcgaa tcagttcaat accggaagag taagaagaag attgctcaac
     5101 catcacgcta tacggcacca ggcctgcatc cagcatcgcc tgttcgtatc ccttctgttt
     5161 gatgatagta cgttcgtcga gacgtgcgcc gagataggca atgtggcgat gcccgcgagc
     5221 aataatggca gtggtcatct ggcgtgccgc ttcaaagtta tcaaaaccga cggcaatatc
     5281 gaggcacggc gacttgctgt ccatcaactc caccaccgga atccccgcca cttcaatcat
     5341 ctttaaggtg cgtggcgtgt gagtacgttc ggtgaggatc aggccgtcga tattccatga
     5401 gagcatggat tcgaggcgtt cttgctccat ttccggttta taaccgtagt gcgccagcat
     5461 ggtttgataa ccgtgcgcgt cggtgacgct ttcgattccg cgtaatactt ccgcgaaaac
     5521 ctggttggtg agagaaggta acaggacgcc aatcgcccgg ctggtggcgt tagagaggat
     5581 atcgggcgcg cgattgggaa tataacccag ttcatcaaga gcggcggcaa tcttgccgcg
     5641 tagagcgacg gaaacctgct ccgggttgcg taaaaaacgg ctgaccgtca ttttggtcac
     5701 gcctacacgg tcagccacat cctgaagtac gggtcttttc tttttcatcg tcctgaaggt
     5761 acaaaagaga tagattcttt tagtttaaca cggacgcctc agaaccttcc cggggaaaac
     5821 agtgcttgtt tacaattatt agatatacac taaatcaatt gcatcgcatt gtgctaacga
     5881 cacggcaaaa ccccggtcgc gtacatcagc acgcgaccgg agcgagcgag gaagcctgca
     5941 aaaaggcagg cttcaaagat gccgttgagt tttaaaccgg cggcagatcg aacagtaaca
     6001 cttcgctgtc gctatccgca tgaatggaga ttgcctgctc atcccagatt gccagaccat
     6061 cgctggtcga ggctttcacg ccgttaatgg tgacattgcc tttcaccacc tggatccaga
     6121 cgcggcgttc agcggcaatc tgatgcaccg actgctcatc tttcagcaat gcccaacgat
     6181 acagttccat atcctgatgc actttcagcg aaccatctcg cgcatccggc gagagcacca
     6241 gctgtttgcc ctgtacggca tcgaagcgac gctgttcata acgcggcgta atgccgtttt
     6301 cttcaggcat gatccagatc tgatacagat gcagacgctc ggtgctgctt gggttgtact
     6361 cagagtgacg gatacccgta cccgcactca taatctggaa ctcacccgcc ggaacctgct
     6421 ctttattgcc catgctgtcc tggtgctcaa cagtaccttc cagcacgtag gtcaaaattt
     6481 ccatatcttt atgcgggtga gtaccgaagc cctgccctgc ttcaatcacg tcgtcgttaa
     6541 tcacgcgcag cgcggagaaa cccataaagt tcgggtcgta gtagttggca aaagagaaag
     6601 tatgccagga gtccagccag ccatgatttg catgaccacg ttcatttgct ttgcgtaagt
     6661 agatcatttg tattcgcccc ctgaatgttt tcgatgggct tagtgtggac ccgatctgcc
     6721 tgggatgata gagggtgaaa attgacccct atgttcaaaa aaattgaact attcgagggg
     6781 ccatcaaact tacttcgcga gagtcactgt ggagggagag gcttgctcaa aaccgcgttc
     6841 aaggatttcc aaattggtaa gaacttcaga ttccttgacg taatttggcg caccgttggt
     6901 gatggtttga tacaacgcat cataaacgcg cccgtaatcg cccatctccg gcttcatctc
     6961 ttctctgacc gtcaccccct cgtcattgac atactccagc acaccgaccg aatcatccgc
     7021 tgcgaatccc ggttcgcccg gcataatatt agccttgagg ctggtttcct gctggtcgat
     7081 accgtattta ataaacgaac ctttcttacc gtgaacgata aatttcggat aatcgatttt
     7141 caccagatgg ctggttttga cgatggcttt caggtcgcca taaaacagct gcgcttcaaa
     7201 ggtgtcgtca ggattggctt tattacgcag gctgcggatg tcataagcga cgtgatccgg
     7261 gcgaccgaac agagaaataa tctggtccat cgtatgcaca ccaaggccat agaacgcgcc
     7321 atcctgcggc agcccaggtt tggtttctgc caccgggcgg taatagtcaa aatggctttc
     7381 cacttcaaca atctctccca gcttgccgct ttcaatcgct tttttcgccg tcagaaaaca
     7441 ggaatcaaag cgacgattct gatacggcgt gacggtcagc cctttacttt tcgccagcgc
     7501 aaaaagttct ttcgcttgcg caagcgtcgg agtgaatggt ttttcgacca gcacattttt
     7561 cccggcttcc agcgcgcgct tcgcgtactc gaagtggctg tccgcatggg tgcagacaac
     7621 aaccagctta acatcgggat cgtttagcac ttcgtcgaga tcgctggtga aatggatatg
     7681 agagtaaatg ggagcctgtt cttccggctt cgcatggcga cgaaaaatat gcgcgacatg
     7741 ccagctatcc ttgcggttaa gtacatacgg cagatggtaa cgggtggtgc ttttgccgaa
     7801 gccaataaag gcgcagttga tgaccatgat ttcgtccttt ttaagggggt tatttacacc
     7861 ttagcgcaaa gcggacgtgg ttcctactgg agtgcgcata acgaacacaa gcacttcccg
     7921 tggataattt gaaaacgaaa gatcaaaaaa aaagccagca cccggctggc taagtaatac
     7981 tggaagcaat gtgagcaatg tcgtgctttc aggttctccg cgagggtctt cctgatcgca
     8041 agacaataat aatcattctc attcgcactt gtccaacact ttttgcaaaa aaatgcattt
     8101 gactcgcatt tgaaagtcaa tgatgttgaa agggacattt accccaaaga ggacaaagga
     8161 atgagtgaga tagtaatacg ccacgcagaa acacgcgatt acgaggccat caggcagatt
     8221 cacgcccagc cggaggtgta ttacaacacg ctacaggtgc ctcatccttc agaacaaatg
     8281 tggctggaac gactcaccgc tcgccctggc atcaagcagt tagtcgcctg tattgatgga
     8341 atcgtcgtag gccatctcac cattgacgtg caacaacgcc cacgccgcag tcatgttgcc
     8401 gactttggta tctgtgtcga ctcccgttgg aagaaccgcg gcgtcgccag cgccctgatg
     8461 cgagagatga ttgaaatgtg cgacaactgg ttgcgggtag atcgtattga gctaacggtg
     8521 ttcgtcgata acgcgccagc aattaaggtc tataaaaaat ttggctttga gattgaaggg
     8581 actggcaaga agtacgcgct gcgtaatggt gaatatgtcg atgcgtatta tatggcgcgg
     8641 gtgaaataga gaatttgcaa tctacgtttg tcatttaagc cctcacctac cgggagaggg
     8701 cttaagatat taataccccg cagttaaatc atccaccgag cgtgggtcgg atgcaccgta
     8761 cagctcaccg tccggcccaa ccataatgct ttgtgtactg cccatcgcct ctttcagcgc
     8821 cactttctga ccttttgctt ccagcagctt gagcgtatcc gggctaaatc ctttctcgac
     8881 acgcagctcg tccggcaacc actgatggtg gaaacgtggt gcattggtcg cttcggcgac
     8941 attcatacca taatcgatgc tattcaccac catttgcagc acggtagtga tgatccggct
     9001 cccgccaggg ctaccggtaa ccagccaggt tttaccgtct ttcaccacaa tggtgggtga
     9061 catcgacgac agcgggcgtt tattcggccc gaccgcgttg gcgtcaccac ccaccagccc
     9121 gtaaacgttc ggtacgcccg gtttggcgga gaaatcatcc atctggttat tgagcaaaat
     9181 accgctctcg cccgcgacaa tgcccgtccc gaaggtggtg ttcagcgtat aggtcaccgc
     9241 caccgcgtta ccgtctttat ccaccactga gtaatgggta gtttgattac tctcataagg
     9301 cgcaagcttg ccggggcgaa tttcgctgga tggcttcgct ttattgatat cgatttgatc
     9361 ggcaatagat ttggcatagg ctttattggt cagcgcctgc cacggtactt tgacaaaatc
     9421 cggatcgcca agatattccg agcggtcggc gtaggcgtat ttctcagctt ctgccatgat
     9481 ttgcatcgcg tcggcactgc caaagccgta cttcttcata tcgaagtttt ccaggatatt
     9541 gaggatctgc acgatatgaa tcccaccgga agatggcggt ggcatcgagt aaacctgata
     9601 cccgcgatat tcgccgctaa tcggtgtacg ttcgaccgct ttatacgccg ctaaatcttc
     9661 tttagtgatc aagccaccgt ttttctgcat ctcctgggca atctgttccg ctatcgtgcc
     9721 tttgtagaat tcgtccgggc cgttttcggc aatcatctcc aggctctttg ccaggttcgc
     9781 ctgcaccagc ttgtcaccct ttttcagcgg cgcgccctct ttccagaaga tagccttgct
     9841 gttttcgtga ttcggcaata cttcgctacc gtaggttttg agatcgtcag ccaacgcgtc
     9901 gttaacgata aaaccatcgc gtgccagttt aaacgccggt tgcaccactt tgttcaacgg
     9961 catggtgccg tacttctcca acgccagcga gaaacctgct accgtaccgg gcgtaccaga
    10021 agccagatgc gaagtgagtg attttttgct gtccgggtta ccctgatcat caaggaacat
    10081 atcgcgggtc gctttggcgg gtgccatttc gcggaaatcg atagccgtgg tattgccatt
    10141 tttcgagcgg attaacataa aaccaccgcc gcccagattc cccgcctgcg gatgcgttac
    10201 cgccagcgcg tagcccactg ccacggcagc atcaacggca ttcccgccct ccttgaggat
    10261 atccaccccc acctgagtgg cagtagcatc tacagacgcc accatcccct gtttcgcgcg
    10321 taccggatga aagacatctt cctccacgcc gtaagaaaca ggagacggcg caggtggcgc
    10381 ggctaccgta ctaaaacaac ttcctgtgaa cagagcagca atggccaccc ggcgtaaaaa
    10441 cgtcggtttt atcatcgtta ttctccagag attaaggggc aaccccagct aagcctggta
    10501 tataactctg aattaatcct gatgattgca ggaaaggagt aaacttaaag aatatcttca
    10561 gaggaggata cgcgatgaaa cgacttctga ttcttacggc actcctgccg tttgtcggct
    10621 ttgcacagcc cattaatact ctgaataacc ctaaccagcc ggggtatcag atccccagtc
    10681 agcagcggat gcaaacccaa atgcaaacgc agcaaatcca gcaaaaaggg atgctgaatc
    10741 agcaactgaa aacgcaaact cagttgcaac aacagcattt agaaaaccag ataaacaata
    10801 attctcagcg ggtgttgcag tcacagccgg gggagcgaaa tcccgcccgg cagcaaatgc
    10861 tgcccaacac caatggcggg atgttaaacg gcaaccgtaa tccggatagt tcgttgaatc
    10921 agcagcatat gttgccggag aggagaaacg gcgacatgct gaatcaaccc ggcacgccgc
    10981 agcctgatat accgttgaaa actattgggc cgtaaagttc ggaccaatca catcaatcgc
    11041 atcggtacag atgcaatcca cgccccagcg cagcaactct gccgcgcgct ggggtttatt
    11101 gacggtataa accagaattc gcagtcctgc atctttcaac tgcatcactc gcgctttatc
    11161 gagcaactta tgattgagat gaatagagac gcagcccagt cgcgcggtca attctcgcca
    11221 gtcgtcgcgc cactcatcaa gcaataaacc gcgcggcagt tctggtactg cttgttgcgc
    11281 ggcgtctaaa gcatcaatct caaacgatga cagcagcggc ggcgtcattc cggcccacag
    11341 ttcgcgtgcc gccagcgcca ccattttgcc cgttaatggc ccggtgccag tggtgggttt
    11401 gatttcgata ttcgccatca tcccgtgttt gcgacaacgt tccgccacct gcgaaagcaa
    11461 cggcagtggc tcacctttaa acgctttgct gtaccaactg cctgcatcca cgcgcagtaa
    11521 atcctgccag ttcagatcgc ccgcgacgcc ccagccgttg ctggtgcgtt caagattgtc
    11581 gtcatggagc aggaagattt cgccatcttt cgataacttc gcgtcaaatt cgatcatctt
    11641 atgaccgtat tttgccccga cgtcgattgc tgccagggtg ttctccgggg ccagtttacc
    11701 gccgccacga tgggcgacga tgcggggata aggccagtta ctcatactcg ttgtcctgtt
    11761 tcaccatcaa aaagatgtag ctgattttcc ggcagatgca gccacagcgt gctgcctgcc
    11821 gtcgggcgct cctgatgtgc cagtcgcacc accagcttct gttcgcccca gcgtccgtgc
    11881 gccaggttat ctgcgccgag gatctccagc gtgtccatca ccagcggcac accaccttct
    11941 gcctgcgagc ttagcgctat atgttccggg cgaatgccga gggtcatttt acgcccggca
    12001 tactgacggt agccaccgtt tagcggcagc gtaatacaac catccagttc gaaatgcgta
    12061 ccttcgttat tcacgcgacc tgccagcagg ttcatcgccg ggctgccgat aaaactcgct
    12121 acaaacaggc tggcgggctt ttcgtagact tccactggcg tgccaatctg ttcggcaacg
    12181 ccgccgttca tcaccattac tcgctgggcg agcgtcatcg cctcaacctg atcgtgagta
    12241 acgtagagtg aagtcgtttt caggcgacgg tgcagttgtt gcagttcaag acgcatctgc
    12301 acacgcagct tggcatcgag gttagagagc ggctcatcaa acaggaacac tgccggctca
    12361 cgcacaatcg cacgccccat cgccacacgc tgacgctgac cgccagatag ctcacgcggg
    12421 cggcgcttaa gcaggccgtc cagctccaga atgcgcgccg cttctttaac acgttcggca
    12481 atttgttgct tgcccatgcc gcgaattttc agcccccacg ccatgttctc ctctacgctc
    12541 atatgcggat agagcgcgta gttctgaaac accatcgcaa tcccgcgatc tttcggctcc
    12601 atttcggtga cacgcttgcg gtcgatccag atatcgcccg tcgttacccg ctccagtccg
    12661 gccaccattc gcaataacgt cgatttcccg cagccagacg gcccgaccat cacgataaat
    12721 tcgccatccg ccacatcaag ggtcagcggt ttaatgacct gggttttgcc atcccagctt
    12781 ttggttactg cctgtaattt cagtcctgcc atcttatttc tcactatcga ccaggccgcg
    12841 cacgaaggca cgctgcatca ctaaaacaat cactactggt gggatcagcg ttaacaacat
    12901 cgccgccatc accgagttcc attccgtggt gccttcgcca gtggcgatca tccctttaat
    12961 ccctgccacg gtggtgccga gatcaacgtc ggtaataatc aacaacggcc acaaatactg
    13021 gttccagccg taaataaagg tgatcacaaa cagcgccgcc agattagttt tggacagcgg
    13081 aaaaacgatg tcgcaaaaga aacgcattgg tgacgcgccg tcgatccgcg cggcttccac
    13141 cagctcatcc ggcagcgtca taaagaactg gcggaacagg aaggtggcgg tcgccgaggc
    13201 catcagcggc agcgttaagc cggcgtagct gtcgagcatc ttcagattgg cgatgacttc
    13261 caccgtcggg aagatacgca cttcaaccgg cagcatcagg gtgataaaaa tcatccagaa
    13321 gaagaggtta cgtagcggaa aacgaaacca gacaatggca aatgccgaga gcatcgagac
    13381 ggtaattttg ccgagcgtaa tgctgaacgc catcacaaag ctgttaagca acatccgcca
    13441 gaacggcgcg ctattcgtgc ctaccccgtt cacccagatg ttgtggatgt tttccagcag
    13501 atgtgtgccg gggattagcg tcatcggtgc ggcatagact tcttgtttat ccagcgtcgc
    13561 cgcgacaaac gccacgtaca gcgggaagag gatcaccgcg atcccgagga tcagcatggt
    13621 atggctgaat attgtcagcc acggacggtt ctcaatcatt ggtaacgtac cttgctttca
    13681 acatagcgga actgcaccac cgtcagcacg atgacgagga acatcaacac caccgactgc
    13741 gcggcagacg aagccaaatc cagtccggta aagccttcac ggtagatctt ataaatcagc
    13801 gtcgtggtgg cctgtactgg cccgccggac gtggcggcgt cgatcaccgg gaaggtgtcg
    13861 aagaaggcgt acaccaggtt caccaccagc aggaagaaac tcaccggagc gataagcggc
    13921 agcgcaatct taaagaagcg gcgaatcggg cctgcaccgt cgatggctgc ggcttcgatc
    13981 aacgaacggg gaatggattg cagcgcggca tagaagaaca gaaagttgta gctaatttgc
    14041 ttccacaccg aggcaaacac caccaggaac atcgcctgac cgctgttttg tgcgtggttc
    14101 cagtcgtagc cgaactcagc gagaaaatgg gtgatcagcc cgcgaccggg gttaaacaga
    14161 aagatccaca atacggcggc aacggcggga gccacggcat acggcagcag cattaaggtt
    14221 tgatagaaac ggctgccgcg cacgatgtac tccaccaacg ccgcgaagaa cagtgacacc
    14281 agcaaaccgc tgacggtgac aaaggtgctg aattttatcg tcgtccagaa ggagtcgaga
    14341 tagtagctgt catgaaacag cgtgacgaag ttatccaggc cgacaaactg gctggagaaa
    14401 ccaaacggat cgacgctttg tagcgagtac cacaacgctt cgcccgcagg ccagataaaa
    14461 aagataacgg tgatgatgag ctgcggcgcg accagcaaat aaggcagcca gcgcgagcgg
    14521 aacaccggac gggatgatga cattacagtt aattcctgaa ctgtgccgga tgcgcttcgc
    14581 ttatccggcc tacacgcgat gccaggtcag ataagcgaaa cgcatccgac attacactga
    14641 ttaagacttc gtcgatttct caaagcggcg cagtaactga ttcccacgct caacggcggt
    14701 atccagcgcc tgctgtggcg tcttcttacc ggtccacacg ctctccagct cttcatccac
    14761 aatcacgcgg atctgcggca tgttgcccag acgcagccct ttggtgaacg gcaacggcgg
    14821 cttgttcagc atctgacgcg tcgcggtatc cgcccctggg tttttctcat aaaagccctg
    14881 ctcacgggtc aggtcatacg ccgctttggt aattggcaga taaccggttt tctgatgcca
    14941 ctcggcagcg ttttctggct tcgcgaggaa gtcgagaaac ttcgccacgc cggtatacgt
    15001 ttctttatct ttgccctgca tcacccacag gctggctccg ccgataatgg cgttttgcgg
    15061 cgcgtctttc gcatcggcat cgtaaggcat catgcctacg ccatagttaa atttggcgta
    15121 ctcgcgaatg ttggcaagag aaccggaaga ggcggtcgtc atcgcgcaat caccgttata
    15181 gaacttctcg gtggattcat ccttacgccc aacgtagctg aaatcgccct tcttgttcat
    15241 ctcttcgagc atggcgatgt gtttcacctg ctccggcttg ttgaactcaa gcaccgcgtc
    15301 tgtgccgtca aagccgttgt ttttgctggc aaacggcaaa ccgttccagg cgctaaagtt
    15361 ttccagttgg atccatccct gccagccgct ggcgtagccg cacttcatac cggaggcttt
    15421 cagttttgcg gcatagtccg ccagatcctg ccaggttttt ggcggctgtt ccgggtctaa
    15481 tcctgctttc ttgaaggcgt ctttgttgta atagagaacg ggagtcgagc tgttgaacgg
    15541 ctgggagagt aagtggccgg ttttgctgtc ggagtaatag cctgaaaccg tcggcacaaa
    15601 ctgcgactca tcgaattgaa tccccgcctc tttaaacacg tcatacaccg gtttaatggc
    15661 tttcgacgcc atcatggtgg cggtgccaac ttcataaacc tgcaaaatag ccggagcgtt
    15721 gccggtacga aatgcggcaa tccccgcgct taaattctgt tcgtagttgc ctttataggt
    15781 cggtacaatt ttgtaatccg ggttttcggc gttaaaacgt tgggccagag aatccacctc
    15841 tttgcccagt tccccttcca tagaatgcca gaacggaatg gtcgtcactg cctgcgcatt
    15901 tgccattaaa gccagtccga gcgccagtgc tgaagctgta taacgtaacg gtttcattga
    15961 ttatctctct tgttgtaccg aatgcgcgaa ttcacgcgtt ttatgctcgc ggggtaacat
    16021 gacatgctcg aattacagaa aaataactat tttgttacat ttttaagata gtaaggtgtc
    16081 agaaagatga caaggcggtg acggcgcggg cgagggaaaa tgggagatgg ggcacggata
    16141 agcgggaaaa atagaaggtc tgaatcaaac tctacagatt gctcatcgtt tcatgccgga
    16201 tgcggcgtaa acgccttatc cggcctacaa gatcgtgcaa attcaatata ttgcaactca
    16261 cccagtaggc ctgataagcg cagcgcatca ggcaatttta catttgtaac ctgtctcaaa
    16321 ggagtctttt gactccttat caatcaacgt gttattaccc gcctaaatac gcacttctca
    16381 ccgcttcgtt cgccagcagc gcatcgccgg tatcggagag caccacatga ccgttttcca
    16441 gaacgtagcc gcgatcagcg agcttcagcg cctggttggc gttctgctcg acgaggaaga
    16501 tggtcatccc ctgctcgcgc agctgctcga tggtgtcgaa aatttgctgg atgataatcg
    16561 gcgcaagacc gagcgatggc tcatcaagca acaataaacg cgggttgctc atcagcgcgc
    16621 gcccaatcgc cagcatctgc tgctcaccgc cggacatggt gcccgcccgc tgaacacggc
    16681 gttcatggag acgcggaaac agttcataca cccactttat gcgttcctgg aactggtcgc
    16741 gttcggcaaa aaagccgccc atcgccaggt tctcttccac cgtcatccgc gagaaaacac
    16801 gacgcccttc cggaacaatc gccaccgctt cgcgcatgat tttcgctgtc tgccagtcgg
    16861 taatgtcttt atcatcaaac acaattcgcc cactggtggc gcgtgggtcg ccgcataacg
    16921 tgccgagcaa ggtggttttc cccgccccgt tcgcgccaat cagcgtgaca atttcgccct
    16981 gattgatatg caggctcacc tcatgcagcg cctggatttt gccgtagtgg gcgctgactt
    17041 tgtcaaagga caacatgact ttttccatct tatgcctcac ctaaataggc acggatcacg
    17101 tccgggttat tacggatctg ctccggcgta ccgtttgcca gcggcgtccc ctgattgacc
    17161 acgtaaattc tgtctgaaat ccccatcacc agcttcatat cgtgttcaat caacaagata
    17221 gtggtgttgt gatggttacg cagttcggca atcagctcat ccagctcttt cgtctctttc
    17281 gggttaagtc ctgctgccgg ttcgtcgagc attaaaatct ccggctgcgt caccatgcag
    17341 cgagcgatct ccagacggcg ctggtcacca taagccaggt tgctcgcctg gcggttggcg
    17401 tgttccagca aaccaatgcg ctcaagccag gtggcggcgc ggtcgagcgc ttcactctgg
    17461 gcgcgacgga aagagggtgt tttcaacagg ccggagaaca gcccggtttt cagttgctga
    17521 tgctgcgcca ccagcaggtt ttcaatcacc gtcatttcac ggaacagacg cacatgctgg
    17581 aaggtgcgca ccacgcccat gcgggcaatt tgctgccccg gcaaaccttc cagatgctga
    17641 tcgcgcagta aaatagtgcc gccggtgggt ttatagaatc cggtcaggca gttgaagacc
    17701 gtggtttttc cggcaccgtt agggccgatt aacgagacga tctcctgcgg gtacagttca
    17761 agattgacgt tgttcaccgc cagcaggccg ccgaagcgca tcatcaggcc gttaacagat
    17821 aataatggct gactcatgcc tgctctcctt tcgctgcgcc gttcttcagc ttgagttgcg
    17881 ggcgcgtcat gggcagcaaa ccctgcggac gccagatcat catcagcacc atcaaaccac
    17941 cgagcattaa catgctgtat tcgttgaaat cacgcatcaa ctcgcgcgat accaccagca
    18001 gaactgccgc cagaatcact gcaaattgcg agcccatacc gccgagcacc actatcgcca
    18061 gcacaaacgc cgattcggca aaggtgaagg attccggact gacaaagccc tgacgcgccg
    18121 cgaacagcgt tccggcaaaa ccggcaaacg cggcactgat ggtaaaagca gtcagcttga
    18181 tacgacgcgg gcttaagccc agcgaacgac aagcgatttc atcttcacgc aacgcttccc
    18241 acgcgcggcc cagcggcatc cgcagcaggc ggttaatgac aaacaggctt aacaccacca
    18301 gcagcaacgc caccaggtag aggaaaatga cgcgatcgga gggatcgtat ttcaggccaa
    18361 agaaattact gaacgtgtcc cagccgcctt cgcgggcagt acgactgaac tcgagtccga
    18421 agagtgtcgg tttggggatc tgactgattc cgttcggacc gccggtgatt tcagtgttat
    18481 tgagcagcaa tatgcgcaca atttcgccga aaccgagggt aacgatcgcc agatagtcac
    18541 cgcgcagacg caacaccggg aagccgagca ggaagcccgc cgccgccgcc atcaacccgg
    18601 caatcggcag acaggtccag aagcccagac cgtaatagtg attgagcagc gcaaaagtgt
    18661 aagcgccgat ggcgtaaaag ccgccgtatc ccagcaccag cagaccagaa agccctacca
    18721 ccacgttcag cccgagacca agaataatgt agatcatggt cagggtggcg atatccaccg
    18781 tcccgcgtga caccataaac ggccacgcca ccgcaagcac cagcagcgcc acgaggaaca
    18841 gtttctgctt caccgtggag ccatcaatcg cgggcagaat aaacttcggc ccggaaacgc
    18901 tttttagccc tttctggaaa gccggtcgca aaagctggaa gaaaaagacc accgccgtgc
    18961 cgataaacac ccactgccaa cggatctctg aagccgtgtc gaccaccagt ttggtgccat
    19021 ccagctccag ttgcacgccc ataaagacgc ccgccagcac aaagaacata gcggcagaga
    19081 gcagcgccat tgcaatatgc atcggtttca tactttctct acctccgggc gacccagaat
    19141 accggtcggc atcaccagca acaccagaat cagcagggcg aatgagacca catctttata
    19201 ttccgtactc agataggcag aagagagcgc ctccgcaatc cccaggatca gcccgccaat
    19261 catcgccccc ggaatgctgc caatcccacc gagcaccgca gcggtaaagg ctttcatccc
    19321 ggccataaag ccgatgtagg ggttaattac gccgtagaac tgaccgagca gcacacccgc
    19381 caccgccgcc atcgccgcgc caatcacaaa ggtcagcgca atcacccgat cggtgttgat
    19441 gccaagcagg ctcgccattt tcagatcttc cgcgcaggca cgacaggcgc gccccatgcg
    19501 ggaatagcga atgaaaatcg tcagcgccag catggcgagg aaagtaacaa tccagatcac
    19561 cgcctgcatg gtggtaatag aggcagagaa gttttcgcta tgccccacca cccactgacc
    19621 gttaaacaga ctgggcagcg ccacgtcgcg cgaaccttcg gtcaggctga catagttttg
    19681 caggaagatg gacataccga ttgcagaaat gagggcaatc aggcgcttgg agttgcgcac
    19741 cgggcgatag gccacccgtt cgatactcca accgtaggcg ctggcaatga cgattgcgcc
    19801 aacgaatccc gccgccacca gcagccagcc ggtatcaatt cccagcatca tcagtgcagc
    19861 gatgatcata aaggagacgt agctgccgat catataaacc tcaccgtggg cgaagttgat
    19921 catgccgata atgccgtaaa ccatggtgta gccgatggct atcagcgcgt aggtactgcc
    19981 cagcgtgacg ccgttaaaca tctgctgcaa gaaatacaaa aactgctcag acataaggta
    20041 acctttctaa acccgcccgt ttttcacggg cagtgggatg atcacttggc tgccgtggat
    20101 gaaccgtcgg cgtgccactg gaagacacca aaatcaaatc ccttaagatc gcctttttca
    20161 tcccagttca gcggcccaat tacggtgttt gcaccgttag cttttaaatc tttcaccagc
    20221 gccagcggct catcgctgcc ggtacgctca agtgcagtcg ccagagattg caccgccgcg
    20281 taagtgatcc agacatatgg cccggacgga tctttcttgt ctgctttcag cgcatcaacg
    20341 atgtcctgat ttgccggatc ctggtcatag cgttttggca tagtgaccaa catgccttcg
    20401 gcagcatcgc cagcaatatt cgacaacgac gcattaccca caccttccgg ccccataaac
    20461 tgggttttca ggccaacgga acgggcctgg cgcagcatct gccccatttc cgggtagtaa
    20521 ccgccgtagt aaacgaagtc gatgttttct tttttcaggc gggcgatcag cgcggagaaa
    20581 tctttctctc cagcggtaat gccgtcgaag aagacgacgt tggcgttagc cgctttcagc
    20641 ccgtcctgca ccgaacgtgc cagtccttcg ccatactgtt gtttgtcgtg aatgatggcg
    20701 atgcgctggg gcttcaccgt ctcaagaatg tattttgccg ccgttggccc ctgggaagag
    20761 tccagcccgg cagtacgcat gatgtattga taaccgcgtt gggtcagctc cggattggtc
    20821 gctcccggcg agatcatcag aataccttcg tcttcataga tatctgatgc aggttgggta
    20881 gaggaggaac acagatgacc aataacatat ttaatgccgt cgttaacgat tttgttggcg
    20941 accgcaacgg cttgtttcgg gtcgcaggcg tcgtcatatt ccacgccaac cagtttatca
    21001 cccttaattc cccctttggc attaatgtct ttaattgcct gacgcgcgcc gttaaattcc
    21061 atatcgcccc actgggcaat cgggccggac atcgcgccga caacggcgac tttaatatcg
    21121 tcagccatag cggtgtgtga aattgtcagt gcaatcatcc ctgcgatgat agttttcgca
    21181 ttccgtttca tagtcaaaaa tccccattcg tgatgttgtg ttgctttgtt tttatgtgtt
    21241 aacaaatcag actgttcttt ttttatactg cactgttttt acctgtctga ttaagggttt
    21301 agcgcagtat tttgtgatga tagcgattaa aatccctatt tttcagtcga ttaataacag
    21361 ataatattct gaatttattg atagataaac agaaaaaagc gccgttgtca gcataaaata
    21421 acggtacaaa gggcagaata attcactacc atttagggga ttatgctgga tatttttcat
    21481 tctctaatgt tttaactttg taattattgc tgaaaaaaaa ttaatcacct gccaaaagaa
    21541 ataaaaaaga gaaagcctcc gattaaatta tttcgctaca ctggttccac ttttgtgatt
    21601 tacacgggtt ccccatgaag ctgaccatca ttcgattaga aaactttagc gaccaggacc
    21661 ggattgacct gcaaaagatc tggccggaat attccccttc ctctttacag gttgacgata
    21721 accaccgcat ctacgccgcg cgttttaacg agcgcctgct cgcggccgtg cgggtaacct
    21781 taagcggcac tgagggggca ctggattccc tgcgcgtgcg ggaagtcacc cgccgtcgcg
    21841 gtgtggggca atatctgctg gaagaggttt tgcgtaccaa tcctggcgtt tcatgttggt
    21901 ggatggcgga tgctggcgtg gaagatcgcg gcgtgatgac ggcgtttatg cgagcactgg
    21961 gatttacggc acaacagggt ggctgggaga agcgttaatc gtcaagtttg atttcacaag
    22021 tgatattgcc tgatgcgcta cgcttatcag gcctacaatg tgtgctgcaa tttactgatt
    22081 tctttggatc ttgtaggccg gataaggcgt ttacgccgca tccggcatga agcaacgtac
    22141 tcgatattag caatttggcg gcaacccaaa gttgccgatt aatgattact tcgcatcggt
    22201 cgccgtgccg ttggcgtgcc agtcaaatac gccgaactca aagcctttca gatcgccttt
    22261 ctcatcccag ctaagcggcc ccatcaccgt atcaaccgag ttcgctttca ggtatttagc
    22321 gatctccgcc ggatcgtcag actgattcag ccccgcttgc aaagattgca gcgcggcgta
    22381 ggtggtccag acgaacgcgc cgcttgggtc ctgttttttc gctttgatcg cgtcaacaat
    22441 cggtttgttc gccggaacct gatcgtagtt cttcggcttg gtcaccagca gcccttccgc
    22501 tgattcgcct gcaatgttag acagcgagac gttagccacg ccttccggcc ccataaactg
    22561 agttttcaac cctgccgcgc gtgcctgacg caggatttgc cccatttccg ggtgataacc
    22621 accgtagtaa acgaagtcga tattctcttt cttcaaacgc gccaccaggg tagagaaatc
    22681 tttttcccca gcggtgatac catcaaagaa caccacgtta gcattgcctt tcttcaggcc
    22741 gtcctgcacc gcacgcgcca gaccttcgcc gtactgctgt ttgtcgtgga cgatagcaat
    22801 acgctgcggt ttcactttct caagaatata tttcgccgcc gtcggcccct ggtcggagtc
    22861 caggccggta gtgcgcagga tcagctgata gccacgggcg gtcagctctg gcgcggttgc
    22921 cgctggggtg atcattaaaa tgccttcatc ttcatagatg tctgacgctg gctgcgttga
    22981 tgaagaacag aggtgaccaa tcacatattt aatgccgtcg ttaacgactt tgttcgccac
    23041 cgcaaccgcc tgtttcgggt cacaggcatc gtcatatttc acgatttgca gtttgttgcc
    23101 tttgatacca cctttagcat tgatatccgc aaccgcctgc tcagcaccag taaactcctg
    23161 gtcaccgtac tgcgccaccg gaccggacat tgcgcctacg acggcgactt taatatcttc
    23221 tgccagagcc atattgctga atgccagcgc gatacatcct gccagtaacg ctttaccctt
    23281 tatgttcatc ctgagaatcc ccactcttct ggttattacg tgtgttgtga tgttgttgtg
    23341 cagcacttta tttcgtttta tacgtagcta cccgtgcttt agcagcatac tctgctaaaa
    23401 cataccccat ttttatgata ttggaatagc tattttgaca gtttattaac aatctgcgtg
    23461 gggattggcg ttttgccgga gggggaaact gattattgta gaggcccaaa aaacaaaaac
    23521 cccggactct catccagggt tctctgctta atagcggaaa ttacgcttca atggcagcgc
    23581 gaagtttttt catcgcgttc ttttccagct gacgcacacg ctcagcggaa acgccgtaac
    23641 ggtcagccag ctcctgcaac gtggacttgt tgtcttcgtc cagccagcgc gcgcggatga
    23701 tatcctgact acgctcgtcc agaccttgca tcgcgtcggt cagacggttt gccgcctgct
    23761 cttcccagtt atcatcttcg atgccgtcgg caaagttaga tgatttatcc tgcagataga
    23821 gcaccggagc catcggctgg ctgtcggaat cgtcgtcgga agacaggtca aaggtcatgt
    23881 cctgtgccgc catacgcgat tccatctcac gtacgtcttt gctggttacg cccagttcac
    23941 gggccaccat ttcgacttca tcctggttaa accagcccag acgctgctta gttttacgca
    24001 ggttgaagaa cagtttgcgt tgcgctttgg tggtcgcaac tttgacgata cgccagttac
    24061 gcaggacgta ttcgtggatc tctgctttga tccagtgaac ggcgaaggag accaggcgca
    24121 cacccacttc cgggttaaaa cggcgcactg ctttcatcag gccgatgtta ccttcctgaa
    24181 tcaaatccgc ctgtggcagg ccatagcccg cataattacg agcaatatga acaacaaacc
    24241 gcaggtgaga caggatcagc gttttagctg cttccagatc gccatggtaa tgcagctttt
    24301 cagccagcgc ccgctcctcg tcagccgaca acatcggcca cgcgttagct gcccggatgt
    24361 aggaatccag gttgccaact ggggctaaag ctaaactttg cattttgtca gtcattcaaa
    24421 tcctctcaat cgatatcttc tggcgcttca gtggtagcaa caactgtgcc agagcttaag
    24481 agcaacgagg ttatcattca ctgttttatc agacagtgat tttatccaca agttcaatgc
    24541 aacgctgtga ataaattacg cacaaaatgt gacatagaga tgaaataccg ggaagagaca
    24601 acggggtctc tttccctgct acggaaccca ttgcagggaa agagtataac acgcttttat
    24661 tattcaggcg taaagtggcg taaatgttgt accgtggcaa gccacgctgc cacccagcca
    24721 atcatcgagc ataccagcag caatagcagg cattcatcga acgataagcc attgatatca
    24781 aactttgttc cgaaaacctg tgccacttcc gcaaccgccg atgacaaacg cagtaccaga
    24841 atttctgaca aaattagtga caacaatgcg ccagaaaatc ccagcaatgc gcctccgtac
    24901 aggaacgggc gcaggatgaa accatccgtc gcaccaatca gtttctgcac gttaatggag
    24961 tcacggcgag caaagatact caggcgcaca ctgttaccga tgacgaggaa cactgctgcc
    25021 accatcaaca cgccgatcat cgcggaaacg cgcccgacca gcccggttaa cgccgccaga
    25081 cgggcaaacc agctgtcatc catccgcact tcgtcaatgc cattgatctg ggtgatacga
    25141 tcacgcagcg tattcagtga ttccgtcccc tgaaaatcga gtttcgggat caccaccgcc
    25201 actgccggaa gcgggttttc ttccagcata tccagcgcac caccaaaacc agaccagtta
    25261 cggaactcgc ccagtgcgtc ttcacgagaa agataattca ctttctccac gccttgctcg
    25321 gcctgcaact gtgccaccac gcccgcagcg gcgtcatcgt ccagcgtttt ttgcagataa
    25381 acagtgattt gcggtgacgg ataatattgc gtcgccgcct ggttaacgtt tttgtacacc
    25441 atataacaga cgctgggcag cgtcagggag atggcgataa ccatcaccgt taaaaacgtg
    25501 gcgaacggtt tgcttttcag atcctgcaat gcgccgtgga aggcatagcg cacctgttcg
    25561 ttgaaaacgt tggttttgcg atttaccggt tttggcgagg atttcgcccg ttttggcgcg
    25621 ttacgaccgc cgtcgccaga gccgccgacc gatttacgga agcgatccag acgcccgcca
    25681 aactgccgaa tatgattgat tgcatcgcgc ttattcatgg cccacgcctc catgcaagtg
    25741 accatcgctc agggtgagca tgcgatagga acgccgcgag atcaggttga tgtcgtgcgt
    25801 tgccatcaat acggttaccc caacgcggtt aaactcttca aacagacgta aaatgccttc
    25861 cgacagcgcg tcgtccaggt taccagtcgg ttcgtccgcc agcagtaccg cgggcttgtt
    25921 caccaccgcg cgggcaatgc caacacgctg ttgttcaccg ccggaaagct gaatagggaa
    25981 gttcttcgct ttgtccagta gcccgacttt atccagcgcc gccgacaccc ggcgacgaat
    26041 gtcatcaccg ctggcaccgg cgataatcag cgggatcgcc acgttatcat agacagtacg
    26101 gtccatcagt agatggtgat cctggaaaat catgccaatc tggcggcgca gaaacggaac
    26161 ttcacggttt ttcagacgcg tgatgtcatg gccgctaaac cagattttcc cggcgctggg
    26221 ccgctcaatc ccacagatca gcttcaggag ggtacttttc cctgcgccgg aatgaccggt
    26281 cagaaacgcc atctcacccg gctgcatatg gaacgtaacg ccctgcagcg cctgtctccc
    26341 accgagataa gccttgctga catgttcaaa gcgaatcatt gttaatcctc tcgggcaaaa
    26401 agtgcctcta taaagtcgtc cgccttaaac ggacgcaaat cctcaatacg ttcgccgaca
    26461 ccaatgtagc ggatagggat accaaactgg tcagccaccg agaaaattac cccgcctttc
    26521 gccgtgccgt ccagtttcgt tagcgtgatg ccggttaagc caacggcttc gtggaacagt
    26581 ttggcctggc ttaccgcatt ctgcccggtg ctggcatcga tggtcagcat aacttcatgc
    26641 ggagcttcaa cgtcgagttt cttcatcacg cggacgattt tcttcaactc ttccatcagg
    26701 tgcgatttgt tctgcaggcg tccggcggta tcggcaatca ggacgtcgat gttacgcgct
    26761 ttagcggcct gaatggcatc gaagataaca gaagcggaat ccgcaccggt atgctgggca
    26821 atcaccggaa tattgttgcg ctgaccccag acctgaagct gttcaaccgc tgctgcacgg
    26881 aaagtatcgc ccgccgccag catcaccgat ttaccctgct gctcaaactg acgtgccagc
    26941 ttaccaatcg tcgtggtttt acccacaccg ttgacgccca ccatcaggat cacgaacggc
    27001 gttttacctt caacattcag cggctcatcg actttcgcca gaatctcgcc catctcttct
    27061 ttcagcaggc catagagcgc ctcggcatca cgaagctgct tgcgggatgc gccttctgtc
    27121 agattggtga taattttacg tgtggtttcc acgcccacat cggcgatcaa cagctgttct
    27181 tccagctctt caaacagatc atcgtcgatt tttttaccgc ggaacaggct gataaatccg
    27241 gaaccgagat tttctttggt ttttaacagg ctgcgtttca ggcgcgcgaa gaaaccttct
    27301 ttggtcggtt tttcctgctc ctgagcgatt tcttccaccg gctgctcttc ttctgccgga
    27361 ggaaccacta tcaccgcctc ttcggcagcc agcgcctgtg cttccagctc ttcgtcggtg
    27421 atttcttctt tagccgcttc ttcttccgcc gcttcgacaa tctctacggt ttccgcttcg
    27481 gcctgccact cttctggcga aacctcttcg gcgttgacgt cttccggcaa cggcagttct
    27541 tcacgctcga tagccactgg ctccggcgtt tcttctgcga ccagttccgg ctgtgcaacg
    27601 acttccgctt caggctgcgc tttttcactt tcagcaacct gttcagtaac ttccacaacg
    27661 tcggcagcaa aagtttccgc ctcggcttca gtatgcgcct gcggctgctc ttcaacggct
    27721 tgttcagaag ccttcacagg ctcttgcgcc tgaacgattt cttctacaac tggttgttca
    27781 ttctgaactt ctgtctcttt ttccggggtc tgctcttttt gaccaaagcc cagccaggaa
    27841 aaaaagccac gttttttttc tttcgccatt tgcgactaca ctcctcgctg ttgcttcatg
    27901 gcacagcgtt aacgctatgt acatagcagc taaaaaaatg atgaaatagt ctatcactta
    27961 acttaattca catcaccgcc tgcaagtatg tgttatctgg cggattgagc aatttatcat
    28021 gaaaaaaccg aatcattccg gcagcggcca aatccgcatt attggcgggc agtggcgagg
    28081 ccgtaaactc ccggttcctg atagcccagg tctgcgcccc accaccgacc gcgtacgcga
    28141 aacgttgttt aactggctgg ctccggtcat tgttgacgcc caatgtctgg attgcttcgc
    28201 cggaagcggc gcgctggggc tggaagcgtt atcgcgctac gctgcggggg ccacgttgat
    28261 tgagatggat cgtgcggttt ctcagcagtt aattaagaat ctggcgacac taaaagcagg
    28321 caatgcacgc gtggtgaaca gcaacgcgat gtcattcctg gcgcaaaaag gcacaccgca
    28381 taatatcgtg tttgtcgatc caccgttccg ccgtggattg ttagaagaga cgataaattt
    28441 actggaagat aacggctggc tggctgacga agccctgatt tatgtcgaaa gcgaagtcga
    28501 aaacggtctg cccactgttc cggcgaactg gtcattacat cgggaaaaag tggcgggtca
    28561 ggtggcttat cggctgtatc aacgcgaagc acaaggagaa agtgatgttg attaatattg
    28621 gacgtttgtt aatgctctgc gtttggggat ttttaatcct caacctggtg catcccttcc
    28681 cgcgtccgct gaatattttt gttaacgtgg cgctgatttt taccgtgctg atgcatggta
    28741 tgcagctggc gctattgaaa tccactttgc cgaaagatgg cccgcagatg accaccgccg
    28801 aaaaggtgcg gattttcctt ttcggcgtgt ttgaactgct ggtctggcag aagaaattta
    28861 aagttaaaaa ataaccttat tgttcgccta caaagctgac aaagcgcgtt cctttatagc
    28921 tcagcgtacc tttatcgccc actgtcaggg cgtggtactg ctgggcgtcg aggcgaaacg
    28981 tctgctccat tcctccgctt tgcggtttga agcttgcctc atagcgcata ctggtgcctg
    29041 ccggagtcac ttcctgctgg cgcgaacggc gatcgttaat cggtttttcc cgcttgttgc
    29101 tcaccaccac cagcttttgc tggagcggtg ccatatcatt atcagctttt tcccgtcgtt
    29161 gttgcataaa acgaaacgat gcggcgacga tgattaagcc aatgataaca ataaagaaaa
    29221 gaggtggttt actcatcttt atccctcatc ggaaaatgcg gaaataagca taccctgcca
    29281 gttatggtgt tgtcatccgt ccaccctcgc cactaaactg gaagcaagac cgtaggcatt
    29341 ccgcttacga aaaaataacg aattcaagga actaagatgc tttggtcgtt tatcgctgtc
    29401 tgtctttccg catggctatc tgtggatgca tcgtatcgtg ggccaacctg gcaacgctgg
    29461 gtgtttaaac cgttaaccct tcttctcctg ctgttgctgg cctggcaagc gccgatgttc
    29521 gacgccatta gctatctggt gctggcgggg ctgtgtgcct cactgctggg cgatgcgcta
    29581 accctgttgc cacgtcaacg tctgatgtac gccatcggcg cgtttttcct ctcgcacctg
    29641 ctgtacacca tctatttcgc cagtcagatg acgctctcct tcttctggcc tctgccgttg
    29701 gtgctgttgg ttctgggcgc gctgttactg gcgattatct ggacgcgtct ggaagagtat
    29761 cgttggccta tctgcacgtt tatcggcatg acgctggtga tggtgtggct ggcaggtgaa
    29821 ctgtggttct tccgtccgac cgctccggca ctctctgcgt ttgtcggcgc ttcgttactg
    29881 tttatcagta actttgtctg gctgggtagt cactatcgcc gacgcttccg tgcggacaac
    29941 gcgattgctg cggcctgcta ctttgctggt cacttcctca tcgtccgctc gctgtatctc
    30001 tgataaaact tgactctgga gtcgactcca gagtgtatcc ttcggttaat gagaaaaaac
    30061 ttaaccggag gatgccatgt cgactcctga caatcacggc aagaaagccc ctcaatttgc
    30121 tgcgttcaaa ccgctaacca cggtacagaa cgccaacgac tgttgctgcg acggcgcatg
    30181 ttccagcacg ccaacgctct ctgaaaacgt ctccggcacc cgctatagct ggaaagtcag
    30241 cggcatggac tgcgccgcct gtgcgcgcaa ggtagaaaat gccgtgcgcc agcttgcagg
    30301 cgtgaatcag gtgcaggtgt tgttcgccac cgaaaaactg gtagtcgatg ccgacaatga
    30361 catccgtgcc caggttgaat ctgcggtgca aaaagcgggc tattccctgc gcgatgaaca
    30421 ggccgccgac gaacaacaag catcacgcct gaaagagaat ctgccgctga ttacgctaat
    30481 cgtgatgatg gcaatcagct ggggtctgga gcagttcaat catccgttcg ggcaactggc
    30541 gtttatcgcg accacgctgg ttgggctgta cccgattgct cgtcaggcat tacggctgat
    30601 caaatccggc agctacttcg ccattgaaac cttaatgagc atagccgcta ttggggcgct
    30661 gtttattggc gcaacggctg aagctgcgat ggtgttgctg ctgtttttga ttggtgaacg
    30721 actggaaggc tgggccgcca gccgcgcgcg tcagggcgtt agcgcgttaa tggcgctgaa
    30781 gccagaaacc gccacgcgtc tgagtaacgg tgagcgtgaa gaggtggcga ttaacagcct
    30841 gcggcctggc gatgtgattg aagtcgccgc aggtgggcgt ttgcctgccg acggtaaact
    30901 gctctcaccg tttgccagtt ttgatgaaag cgccctgacc ggagaatcca ttcctgtgga
    30961 gcgcgcgacg ggcgataaag ttcctgcagg agccaccagc gtagatcgtc tggtaacgct
    31021 ggaagtgctg tcagaaccgg gtgccagcgc cattgaccgg attctgaaac tgatcgaaga
    31081 agccgaagag cgccgcgcgc ccattgagcg gtttatcgac cgcttcagcc gtatttatac
    31141 gccagcgatt atggccgtcg ccctgctggt aacgctggtg ccgccgctgc tgtttgccgc
    31201 cagctggcaa gagtggattt ataaagggct gacgctgctg ctgattggtt gcccgtgtgc
    31261 tttagttatc tccacgcccg cggcgattac ctccgggctg gcggcagcag cgcgtcgtgg
    31321 ggcgttgatt aaaggcggcg cggcgctgga gcagctgggt cgtgttaccc aggtggcgtt
    31381 tgataaaacc ggtacgctga ccgtcggtaa accgcgcgtt accgcgattc atccggcaac
    31441 gggtattagt gaatctgaac tgctgacact ggcggcggcg gtcgagcaag gcgcgacgca
    31501 tccactggca caggccattg tgcgcgaagc acagattgct gaactcgcca ttcccaccgc
    31561 ccaatcacag cgggcgctgg tcgggtctgg cattgaagcg caggttaacg gtgagcgcgt
    31621 gttgatatgc gctgccggga aacatcccgc tgatgcattt gctggtttaa ttaacgaact
    31681 ggaaagcgcc gggcaaacgg tagtgctggt agtacgtaac gatgacgtgc tgggtatcat
    31741 tgcattgcag gatactctac gcgccgatgc tgcaactgct atcagtgaac tgaacgcgct
    31801 gggcgtcaaa ggggtgatcc tcaccggcga taatccacgc gcagcggcgg caattgccgg
    31861 ggagttgggg ctggagttta aagcgggcct gttgccggaa gataaagtca aagcggtgac
    31921 cgagctgaat caacatgcgc cgctggcgat ggtcggtgat ggtattaacg acgcgccagc
    31981 gatgaaagct gccgccatcg ggattgcaat gggtagcggc acagacgtgg cgctggaaac
    32041 cgccgatgca gcattaaccc ataaccacct gcgcggtctg gtgcaaatga ttgaactggc
    32101 acgcgccact cacgccaata tccgccagaa catcactatt gcgctggggc tgaaaggcgt
    32161 tttcctcgtc acgacgctgt tagggatgac cggactgtgg ctggcggtgc tggcagatac
    32221 gggtgcgacg gtgctggtga cggcgaatgc gttaaggctg ttgcgcagga aataaggcaa
    32281 accgatcgca acattgagcg cgatcggtcc cctcgctcct ctggggagag ggttagggtg
    32341 aggggaaaag gcggcatcga agccaatctt cccccatcaa ccgcctttac gaatcaaata
    32401 acgataaggc agtccatccg tctctttcgc aaccagttcg tgttccataa aggtacaaaa
    32461 cccaggaata tcgcgggtcg tcgccggatc gtcagcaata atcagcaacg tttcacctgg
    32521 ctgcatattg cgcactgttt tgcgcaccat cattactggt tccgggcagc gcaggccaag
    32581 tgcgtcgagt gtgtggtcag ggctggaaaa gagatcggtc attttcttct catcacataa
    32641 aaaaacggcg ctagtttacg ccctgtgagt ccgtaagcaa accaggttaa cgattgcgtg
    32701 aaaattaacc attgcattgt taacgtaaag cagtatcatg cggcggctcg aaaaaagggt
    32761 cagcacgtta ttatgttaag gtaacagacg tgtcgtacgt attgggttcc ctcaccccaa
    32821 tggttaatca aaaaggtaca atatgaacgt tttctcgcaa actcaacgct ataaggcgtt
    32881 gttctggtta tcgttatttc atcttctggt gatcacctcc agtaactatc tggttcagct
    32941 tcccgtatcc atttttggtt tccataccac ctggggcgcg tttagctttc cgtttatttt
    33001 ccttgctacc gacctgactg tgcgtatttt tggcgcaccg ctggcccgtc gtatcatctt
    33061 tgcggtgatg atcccggcgt tactgatctc ctacgtcatc tcgtcgctgt tctatatggg
    33121 ttcctggcag ggattcggcg cgctcgccca cttcaacctg tttgtcgccc gtatcgccac
    33181 cgccagtttc atggcctacg cgctggggca aatcctcgac gtgcacgttt ttaaccgcct
    33241 gcgtcagagt cgtcgctggt ggctggcacc gacggcttcc accctgtttg gtaacgtcag
    33301 cgacacgctg gccttcttct tcattgcctt ctggcgtagc ccggatgcct ttatggctga
    33361 acactggatg gaaatcgcgc tggtcgatta ctgtttcaaa gtgttaatca gtatcgtttt
    33421 cttcctgcca atgtatggcg tattactcaa tatgctgttg aaaagactgg cagataaatc
    33481 cgaaatcaac gctttgcagg cgagttaaag gttcgttatc agagttgtga taagatggat
    33541 gaatgagccg ttatggccgt ttatcgaaag gaagaagtca atgcgcaatc tggttaaata
    33601 tgtcggaatt ggcctgctgg ttatggggct tgcggcctgt gatgataaag acactaacgc
    33661 tacggcgcag ggttcagtcg cggaaagtaa cgctaccggg aatcccgtca acctgcttga
    33721 tggcaagtta agtttctcgc tgccagcgga tatgaccgac cagagcggta agctgggaac
    33781 gcaggctaat aacatgcatg tctggtccga cgccaccggg caaaaagcag tcatcgtcat
    33841 catgggcgat gatccgaaag aagatctggc ggtgctggcg aagcgcctgg aagatcagca
    33901 acgtagccgc gatccgcagc tgcaagtggt aaccaataaa gccattgagc tgaaaggtca
    33961 caaaatgcag cagttagaca gcattatctc cgcgaaaggc cagacggcgt actcttccgt
    34021 tattctgggt aacgtgggta atcaactgct aaccatgcaa attacgctgc ccgctgacga
    34081 tcagcaaaaa gcacagacca ccgcagaaaa catcattaat acgctggtta ttcagtaagt
    34141 tttaagatga tgagatggcc tcaggtactt ccaccggagg ccgttttttt aatcgccacg
    34201 tcagtaataa cgcgattgcg accagtcccg ccgccgccag ataaatcacc gggacgcccg
    34261 cccaactcat caccagccca gccagtggtc cggtcacgcc aagcgataaa tccataaata
    34321 cggtgtaagt tgccagcgcc gccccctgat tttgctgcgg aaccgctttt accgccacta
    34381 cgcccaatgc cgggaacacc agcgaaaacc ccgcccccgc gagtaagacg ccgattttcg
    34441 ccatccacgg catagtcgcc acgccaacca gtagcaggcc gattatctca acgctaaagc
    34501 aaatcatcgc cacgtttaag ccgccgatac ggttaatgcc gttaggaaat aacaaacgcg
    34561 taccgacaaa cgcacagcta aacagcgtca gcgcgaaagc cgcaccgtcc caacctttag
    34621 cgtcataaaa cagcgtgata aaggtggcga taacgccaaa tccggcggaa gccagtgcca
    34681 gcgccatacc gtacagccag acgcgcccaa gcaccgcgcg aaacggcagc ggtttgcctt
    34741 tactggcttt taccgtcgga cgcgggatcg ccaacaaaat ggccaccagc gccacgccca
    34801 taatgattaa cgctaacgcc tgcaagccgc cccagtgata aaacacgaca cctaacggcg
    34861 cacccatcgc catcgccccg taagtgacaa tgccgttcca cgaaatcacc cgcccgatat
    34921 gcagcgaacc aaccacgcca acgccccata gggtcgatcc cgttccggca aaactttgcc
    34981 caatcccaag gatcacgcgc cccaggcaca gtaataacag gctgatgacg ggcagactgg
    35041 cggttaatcc tgccgtcaga taccccaaac cgctcaaaaa gcagccgcat aaaccgaaga
    35101 cgacaatctt tttgggtccc agcaaatcgg cgtaacgtcc ggcatgaggg cggctcagca
    35161 aggtggcgaa atattgcagg ctgataacca atcctgccca gaaagcgcta aagcccatca
    35221 catcatggac atagcccggt aatacagcga gcggcaaccc gatggtgagg tagctggcga
    35281 agttaaacat gacaatggag acaatgcgca aattcaggcg caatccgttt agcgcgggtt
    35341 cggctacggg ttcgggcatg aggatcacca catttttaca acagtgtttc atttttacca
    35401 cgtgctgacg tgaaaatcag cagtaagaat cagaatattg ctggcgtgac tcccgctaca
    35461 cttaatacaa aaagtcacaa ggaagcccca atggaaaccc ctcaacccga taaaacgggc
    35521 atgcacattc tgctcaagct ggcctcgctg gtggtgatcc tcgcgggaat tcacgcagcg
    35581 gcagatatca ttgtgcagct gttactggcg ctgttttttg ccatcgtcct caacccgctc
    35641 gtcacctggt ttattcgtcg gggagtacaa cgccccgttg ccattacgat tgtggtggtg
    35701 gtgatgctga tcgcactaac cgcgctggtc ggcgtactgg cggcatcgtt taacgaattt
    35761 atctctatgc tgccgaagtt taataaggag ctgacgcgca aactttttaa attgcaggag
    35821 atgttgcctt ttcttaattt gcatatgtcg ccggagcgaa tactgcagcg gatggactcg
    35881 gaaaaaatgg ttaccttcac cacggcgcta atgaccgggc tttccggggc aatggcgagc
    35941 gtgcttttgc tggtgatgac cgtagttttc atgctgtttg aagtgcgcca cgtcccttac
    36001 aaaatgcgtt ttgcgttgaa taatccacag attcacatcg ccggactaca ccgcgcctta
    36061 aaaggtgttt cgcactatct tgcattgaag acactgctaa gtttatggac aggcgtaatc
    36121 gtctggctgg ggctggcgct aatgggcgta cagtttgcgc tgatgtgggc agtactggcg
    36181 tttttgctca actacgtgcc caatatcggc gcggtaattt ccgccgtacc gccaatgatt
    36241 caggtgctgc tgtttaatgg cgtttacgaa tgtattctgg tcggcgcatt gtttttagtg
    36301 gtccatatgg tcatcggcaa tattttagaa ccacggatga tgggccatcg cctggggatg
    36361 tccaccatgg tggtatttct ttcattgtta atttggggat ggctgctcgg cccggtaggg
    36421 atgctacttt cggtaccatt aaccagcgtg tgtaaaatct ggatggaaac caccaaaggc
    36481 ggtagcaaac tggcgatttt actgggaccg ggcagaccga aaagtcgatt accgggatga
    36541 ggcgacaagt gttacgatac gcactttcat tttccattaa acgttggccc tgatatgtat
    36601 cggatagttc tggggaaagt ttcgacctta agcgcagctc ctctgccacc gggtttacgc
    36661 gagcaagcac cgcaaggtcc acgacgcgaa cgctggctgg cggggcgtgc attgctttcg
    36721 cacacgcttt ccccgctacc ggagatcatc tatggcgaac aaggcaaacc tgcattcgcg
    36781 ccggaaacgc cgctatggtt caacttaagc catagcggtg acgatatcgc cctgctgttg
    36841 agcgatgaag gcgaagtcgg ctgcgatatc gaagtgattc gcccgcgcgc caactggcgc
    36901 tggctggcga acgccgtatt cagccttggg gaacatgccg agatggacgc cgtgcatcct
    36961 gatcagcaac tggaaatgtt ctggcgcatc tggacgcgca aagaagccat cgttaaacag
    37021 cgtggcggca gcgcctggca aatcgtcagc gtagacagca cctataactc ctcgctgtca
    37081 gtcagccatt gtcagctaga aaatttaagc ctggcgatct gcacccctac cccctttacg
    37141 ctcaccgccg acagtgtgca atggatcgat tcagttaact gatccgccca cccgactgcc
    37201 catctattga tccagaacag gtaatcagta tgacgaatac ttaaaatcgt catacttatt
    37261 tccgccatct attttaatcc attggggtta ccatgttctc tacactccgc cgcactctat
    37321 ttgcgctgct ggcttgtgcg tcttttatcg tccatgccgc tgcaccagat gaaatcacca
    37381 ccgcctggcc ggtgaatgtc gggccactaa acccgcacct ttacacgcct aaccaaatgt
    37441 tcgcccagag catggtttat gaaccactgg tgaaatatca ggcagacggt tcggtgatcc
    37501 cgtggctggc aaaaagctgg acccattcag aagatggcaa aacctggacc ttcaccctgc
    37561 gtgatgatgt gaaattctct aacggtgaac cgtttgatgc agaggccgcg gcagaaaact
    37621 tccgcgctgt gctcgacaac cgtcaacgtc acgcctggct ggagctggca aaccagattg
    37681 ttgatgtcaa agctctcagt aaaaccgagc tgcaaatcac cctgaaaagc gcctactacc
    37741 ctttcctgca agaactggcc ctgccccgtc ctttccgctt tatcgccccc tcgcagttta
    37801 aaaaccatga aaccatgaat gggattaaag cgccgattgg caccgggccg tgggttttgc
    37861 aggaatcgaa actgaatcag tacgatgtct tcgtccgtaa cgaaaactac tggggcgaaa
    37921 agccggcgat taagaagatc acttttaacg tcatcccaga cccgactacc cgcgcagtag
    37981 cgtttgaaac cggcgatatc gatctactat acggtaatga agggctatta ccgctcgata
    38041 ccttcgcccg ctttagccag aactcggctt accacaccca actgtcacag ccgatcgaaa
    38101 ccgtgatgct ggcgctcaat actgccaaag cccccaccaa cgagctggca gtccgtgaag
    38161 ctcttaatta cgcggtaaac aaaaaatcgc tgatcgataa cgcgttgtat ggcacccagc
    38221 aggtcgccga caccctgttt gccccttccg tgccctatgc caatctcggc ctgaaaccgc
    38281 gccagtacga tccgcagaaa gcaaaagcgt tgctggaaca agcaggctgg acgctgcccg
    38341 caggcaaaga catccgcgag aaaaatggtc agccgctgcg cattgaactg tcgttcatcg
    38401 gcaccgatgc gttaagcaaa tcaatggccg aaatcattca ggctgatatg cgccagattg
    38461 gcgcggatgt cacgctgatc ggcgaagaag agagcagtat ctatgctcgt cagcgcgacg
    38521 gtcgttttgg catgattttc caccgtacct ggggcgcgcc atacgatcca cacgccttcc
    38581 tgagttcaat gcgcgtaccg tcgcacgctg acttccaggc acagcaaggt ttagccgaca
    38641 agccactgat tgataaagag attggcgaag tgctggcgac acacgacgaa acacaacgtc
    38701 aggcactgta tcgcgacatt ctgacccgtc tgcataacga ggcggtttat ctgcccatca
    38761 gctatatctc aatgatggtg gtttcaaaac cggaactggg taacatcccc tacgcgccga
    38821 tcgccaccga aatcccgttc gaacagatta aaccggtgaa accttaatgt tgcgttatgt
    38881 attacgccgc tttctgctgc tgatcccgat ggtgctcgcc gcctcggtga tcatttttct
    38941 gatgctgcgc ctcggcaccg gcgacccggc gctcgattat ctgcgtctgt ctaacctgcc
    39001 gccgacgccg gaaatgctgg cttctacccg caccatgctg gggctggatc agccgttgta
    39061 cgtgcagtac ggaacctggt tgtggaaagc gctgcatctt gactttggta tctcattcgc
    39121 cagccaacgc ccggtgctgg acgatatgct gaccttcctg cccgccacgc tggagctggc
    39181 gggtgcggcg ctggtattaa ttctgctcac ttccgtgccg ctcggcatct gggcggcgcg
    39241 ccatcgcgac cgcctgccgg atttcgccgt gcgttttatc gcgtttcttg gcgtgtcgat
    39301 gcctaacttc tggttggcgt ttttactggt gatggcattt tcagtgtatc tgcaatggct
    39361 gcccgcgatg ggttacggcg gctggcagca catcattttg cctgcggttt ccatcgcttt
    39421 tatgtcgctg gcgattaacg cgcgtctgct gcgcgccagt atgctggacg tcgccggtca
    39481 gcgtcatgtg acctgggcgc gactgcgcgg cctgaacgac aaacagaccg aacgccgcca
    39541 catcctgcgc aatgcctcgc tgccgatgat caccgccgtg gggatgcaca ttggcgaact
    39601 gattggcggg acgatgatta tcgaaaacat ctttgcctgg ccgggcgtcg ggcgctatgc
    39661 ggtgtcggcg atttttaacc gtgactatcc agtgatccaa tgctttacgc tgatgatggt
    39721 ggtggttttt gtggtctgta atttgattgt cgatttgctc aacgccgcgc tggacccgcg
    39781 tattcgtcgt catgaaggag cgcacgcgtg aactttttcc tctcctcccg ctggtcggtt
    39841 cgcctggcgc tgatcattat cgccctgctg gcgctgattg cgctcaccag ccagtggtgg
    39901 ctgccgtatg accctcaggc gattgatctg ccgtcgcgcc tgctttcacc ggatgcgcag
    39961 cactggctgg gtaccgatca tttagggcgc gatattttct cgcggctgat ggcggcgacc
    40021 cgcgtgtcgc tcggctcggt aatggcctgc ctgctgctgg tgctgacatt agggctggtt
    40081 attggcggca gcgccggact gattggcggg cgcgttgatc aggccaccat gcgcgtcgcg
    40141 gatatgttta tgaccttccc gacctcgatt ctgtcgttct ttatggttgg cgtgctcggc
    40201 accgggctga ccaacgtaat tatcgccatc gccctgtcgc actgggcgtg gtatgcacgc
    40261 atggtgcgca gcctggtgat ttcgctacgc cagcgcgagt ttgtactggc atcacggctt
    40321 tctggcgcgg gccatgtgcg ggtgtttgtc gatcatctgg caggcgcggt gatcccctcg
    40381 ctgctggtgc tggcgacgct ggatattggt catatgatgc tgcacgtcgc ggggatgtcc
    40441 ttcctcggcc tcggcgtgac cgcaccgacc gccgaatggg gcgtgatgat taacgacgcg
    40501 cgccagtata tctggaccca gccgctgcaa atgttctggc cggggctggc gctgtttatc
    40561 agcgtgatgg cctttaacct ggtgggtgac gcactgcgcg atcatctgga ccctcatctg
    40621 gtgacggagc acgcacacta atgccgcaac agattgaact acgtaatatc gcgctacagg
    40681 ccgcgcagcc gctggtgcac ggcgtatcgt taacccttaa acgcgggcgt gtgctggcgt
    40741 tagtcggcgg tagcggcagc gggaaatcac tgacctgcgc cgcgacgctg ggcattctgc
    40801 ccgcaggcgt tcgccagacg gcgggggaaa ttttagccga tggcaaaccg gtttctccct
    40861 gtgccctgcg cggcatcaaa attgccacca tcatgcagaa cccgcgcagt gcctttaatc
    40921 cgcttcacac catgcacacc cacgcgcggg aaacctgcct ggcgctgggg aaacccgccg
    40981 atgacgctac gcttaccgct gccatagaag cggtggggct ggaaaacgcc gcacgcgtgc
    41041 tgaagctgta cccgtttgag atgagcggcg gcatgttgca gcgcatgatg attgcgatgg
    41101 cggtgttgtg tgaatcgccg tttatcatcg ccgatgaacc gaccaccgat ctcgacgtgg
    41161 tagcacaggc gcgcattctc gatctgctgg aaagcattat gcaaaaacaa gcaccgggaa
    41221 tgctgctggt gacccatgat atgggcgttg tggcgcgtct ggcggatgac gtggcggtga
    41281 tgtcacacgg taaaattgtc gaacagggcg atgtagaaac gctgtttaat gcccccaaac
    41341 atgcggtaac gcgcagcctg gtttccgctc atctcgccct ctacggtatg gagctggcat
    41401 catgacttta cttaacgtct ccgacctttc ccatcactat gcgcacggtg gatttagcgg
    41461 aaaacatcaa caccaggcgg tgctgaataa cgtttccctg accctgaaaa gcggcgaaac
    41521 cgtcgctctg ctggggcgca gcggctgcgg aaaaagcact ctcgcgcggc tgctggtagg
    41581 cttagagtct ccctcacaag ggaatattag ctggcgcggc gaaccgttgg caaagctcaa
    41641 tcgcgcccag cgtaaagcgt tccgccgcga tattcagatg gtatttcagg actccatcag
    41701 cgccgtgaat ccgcgcaaaa ccgtgcgcga gatcctgcgt gaaccgatgc gccacctgct
    41761 atcgctgaaa aaagccgaac aactggcgcg cgccagcgaa atgctgaagg cggtcgatct
    41821 cgatgacagc gttctagaca aacgcccacc gcagttaagc ggcggtcagc tccagcgcgt
    41881 ctgcctggct cgcgcgctgg cggtcgaacc gaaactactg attctggatg aagccgtttc
    41941 taaccttgat ctcgtgttac aggcgggcgt cattcgcctg ctgaaaaagc tacaacaaca
    42001 gtttggcact gcctgcctgt tcatcactca tgacttacgc ctggtggaac gcttttgcca
    42061 gcgagtgatg gtgatggaca acggacaaat cgtcgaaacc caggtggtgg gagataaatt
    42121 aaccttttcc tctgacgccg gacgtgtgct acaaaacgcg gtattacccg cataccccgt
    42181 gcgccgtcgc gccacagaaa aggtttaagt ctatgcaacg agttaccatc acgcttgatg
    42241 acgatttact ggagacgctg gacagcctga gccagcgtcg tggctataac aaccgttccg
    42301 aagctatccg cgatattctg cggagtgccc tggcgcagga agctacccag cagcacggca
    42361 cacaaggttt cgcggtgctg tcgtatgtgt atgaacacga aaaacgcgac ttagccagcc
    42421 gtattgtctc cacccagcat catcaccacg atctctcggt cgccacgctg catgtgcaca
    42481 ttaatcacga cgactgtctg gaaattgccg tgctgaaagg tgacatgggc gacgtgcagc
    42541 attttgccga tgacgtcatc gcccagcgcg gcgtgcggca cgggcatttg cagtgcttgc
    42601 cgaaggaaga ttgagttatt tctaaaacga ggaaagaaaa gatattaact gaacttaatt
    42661 tataaaatta agttcagtta catagataga tcctgtaaag gcagatactc tgcgtaatgc
    42721 acgccgctaa aatttataaa tgattcaaac gctcatttag cgtttcaata atataagtat
    42781 ttacagagac ttgttgctgc gcagccgcat tattaaggcg ttcactcagc gattctggat
    42841 agcgtaatgt aaaggtctta atcttttctg tacgcgcata cggctcaata cccgcagctt
    42901 tacaatcctc aagatactct cgcagggaaa gctccccttc tttttgcagc ccctgaatgc
    42961 tgtcagagac aaaatcacaa taacctgaca agcccaggaa tttgccacga aatgcattca
    43021 gttctggcac gtaagtgata acagcaggtt gcccggcaat ctccatagag tttggcgtct
    43081 tcagtttgat catggtttta cccctatact tagtaaccag tcacgcacgc tttctacagc
    43141 gcctttatcg gtatctggcg acggatgagg ccgatggaaa cacgcaacgc tcatatttag
    43201 tatgaactta caacgcgaac ctcttccttc cttaatttct ccgcctaatg ctttaaccag
    43261 tgactctata tcagaccact taatccctta aggaacagga gatttaaata tttgatccaa
    43321 tgtatttttt tgtttcttcc gtaaagcctg tacctgggtt ctcatggcat gtccttatga
    43381 cttcacttta tgacatcaat agtatgacat cacaatatga agtcaagttt cccttcctta
    43441 cgccattgtc ccaatcgtct tcctgaatcg cagcagtgcg atggtgaaaa atgcgccgcc
    43501 aattgccatc agcgtcagga actgcggcca gacgatttcg aatccggcac cacggtagag
    43561 aatggcctgc gcgaggctaa caaagtgtgt cgtcggcatg gtcagcataa tgtcctgcac
    43621 catctgcggc atactttcgc gcggcgtgga gccaccggaa agcatttgca gcggcagcag
    43681 caccagaatc accagcagcc ccagttgcgg catcgaacgc gctatcgtcc ccataaaaat
    43741 gccgattgac gtggtggcaa acagactcag cgccacgccc agcataaaca gcgggatcga
    43801 gccttcaatc ggtacgccca gcacgccttt caccatcagt accagcgata atcccgacac
    43861 caccagcacc accagcccca tcgaccagac cttcgccatc atgatctcaa acggcgttat
    43921 cggcatcacc agtaagtgtt ccaccgtgcc gtgttcacgc tcgcggatca gcgccgatcc
    43981 ggtcaacaca atcgccagca tggtaatgtt gttgatgatc gccatcaccc cgccaaacca
    44041 cgcgggatcg aggttcgggt taaagcgcat ccgggtttcc agcgatacca acggttcgct
    44101 gttatcacgg tagcgcgcga caaagctgtt cacttcaccg ttgataatat tctggatata
    44161 cccgttgccg gtaaatgcct ggctcatgcg cgtggcatcg acgttcacct gaatatctgg
    44221 ctggcgcccg gcgaggacat cacgctgaaa attaggcgga atatttatcg caaaggtata
    44281 acgcccggcg tccagcccgg catccatctc atcggcggtg atcatctccg gtggcaaaaa
    44341 ccacgggcga tagaagctgt taacgatcct gttcgataac tgcgattgat ccatatcggc
    44401 aatggcgatc ggcgcgaggt tcaacgatcc tggcgtaacg gtcgctgacg aatacaccga
    44461 caccgtaaac gagaagacaa tcagcgtcag catcgcttta tcaccgagca aactgcgcaa
    44521 ctctttgata cccagattaa aaatattgcg taaatggcgc atcatccctc ctgttttttc
    44581 agcagcagga tgcttaagcc caccaccagc gggatggcta tcagcaacgg gataaaaagt
    44641 tgccacaaat cagtcagatc cagcgccttc gagaacgtcc cgcgggcgat agtcagaaaa
    44701 tgactggtcg ggtaaacctc gccgatccaa cgtcctggac cttccagcga agctaccgga
    44761 tcgatcatcc cggaaaactg cgtcgccgga atcaacgtga tgatcgcagt gccaaaaata
    44821 gcggcaatct ggcttttcat aaaggtggag atcagcagcc ccattccggt ggcaatgatg
    44881 atatacagca gcgccgccag ggtgagcgtc aggaaactgc ctttatgcgg tacgccaaac
    44941 acaaacaccg acaggccgca gagcaggaaa aagttcagca tccccagcgc gatgtatggc
    45001 aactgtttac caagcaaaaa ttcactacgc gtggtggggg tcacgtaaag gttgataatc
    45061 gacccaagct ctttttcccg caccacgcta agggcgctta gcattgacgg gatcatcatc
    45121 agcagaagcg ggatcaccgc cggaacaatc gctggcaggc tttttacgtc cgggttatag
    45181 cgatagcgcg tctcaatgtt catcagcccg ctttggctgg cgggtgtcga ttgtcggctc
    45241 gccacatcct gaagccaact ctggtgcatt gcctgcacgt aaccttttac cgtttcggca
    45301 cgactgggca tcgctccgtc gatccagacg ccgagttcca caggcgtacc acgcgcgata
    45361 tcgcgcccaa aattgggagg gatctcaatt gccaccgtga tatcgcccgc acgcatccga
    45421 cgatccagct cgtcataact ggtgagcggc ggctgttcga taaagtaacg ggaaccggag
    45481 agattgagcg tccacgcctg gctactgacg gtctggtcgc ggtcgagcac agcaaagcgc
    45541 aggttttcca catccatact gatgccgtaa cccattatca gcatcaggat caccgttccc
    45601 atcagcgcca gcgtcgaacg tactggatcg cgtcgcagtt ccagcgcttc gcggcggctg
    45661 tagctaaaca gacggcgcag gctaaatccc tgacgcggcg cgtgggtggt gtcgtgtacc
    45721 acgggcggcg cttcggcttc gttgctctgc cctgccgctt cctgcaaata ggcgataaat
    45781 gcctcttcca gactggcggc tccgcgtttc tcaaccagtt cctgcggtgt accgctggca
    45841 agcacttttc cggcgtgcat cagtgagatg cggtcgcaac gttccgcttc gttcataaag
    45901 tgggtggaga tgaagatagt cactttgtcc tggcgcgaga gatcgaccat caactgccag
    45961 aacatatccc tcgccaccgg atcgacacca gaagtaggct catcgaggat taacatctcc
    46021 gggcgatgaa tcaccgccac cgccagcgaa agccgctggc gaatgccgag cggcaatgac
    46081 tccggcagaa catcttcaac gtcgttgagc ttaaaacgct cgctcatttc agccactcgc
    46141 gcgggaattt ccgcttccgg gatatgaaac agacgagcat gtaactccag gttttgccgc
    46201 acggtgagtt cgttatagag cgaaaacgcc tgcgacatat agcccacccg acggcgagta
    46261 tcgatatctt ttggatcaac cggttgcccg aacagccacg cctcaccttc gctggcgggc
    46321 agcaatccgg taagcatttt catggtggtg gatttaccgc agccgttcga accaagaaaa
    46381 ccaaaaatct ccccgcgtgg aatgcggaaa ttgacgtgat caacggcaac gaaggaacca
    46441 aaacgcatgg tcagatcgcg cgcttcgatg gcaatctctg cgttttcagg ttgatatggt
    46501 gggatcacta ccgcctgatg cgcctggcgt tgcgcttgcg gtaacagatt tataaatgct
    46561 tcttccagcg tggcgctttg cgtttgctgc cgcagctctt cggcgctgcc agttgccagc
    46621 acttctcctg cattcatcgc taccagccag tcgaagcgtt ccgcctcttc catataggcg
    46681 gtggcaacca gcacgctcat attgctctgc cgctggcgaa tactgtcgat cagatcccag
    46741 aactgggcgc gggagagcgg gtcaaccccc gttgttggct catcaagaat caacagttcc
    46801 gggtcgtgaa ttaacgcaca gcacagccca agtttttgct tcatcccgcc ggagagtttc
    46861 cctgccgggc gatcgcgaaa cggtgctaac ccggtgctgg tcagcagctc attgattcgc
    46921 acttcccgct ccgctttgtc gtgaccgaac aggcgagcga aaaaatcgac gttttcatac
    46981 accgacaagg tgtggtagag atttttgccc agcccctgcg gcatccaggc gatgcgcggg
    47041 cagacgtcgc ggcgatgctt cgggtcgcgc atatcgccgc ccagcacgat cacattgccc
    47101 tgctcaatga cgcgggcacc ggaaatcaat gacaataaac tcgacttccc gacgccatcc
    47161 ggaccaatca gcccaaccat gcagcgggcc ggaatatcga gagtgatatt gttcagcgca
    47221 acggtttttc cataatgctg gctcacgccc gccagttgcg cgacaggcgg gacgggaacc
    47281 agttccagat gcgtcattgc ggcaacctca ccgccaggtc ttcaggccac ggaagttctt
    47341 cattcacccg cacccacgct acgcccggca aaccggtttt gacatattcc agatgctgct
    47401 ggagtaattc cggtgggata cgcgctttga cacggaacat cagtttcagc cgttcatcgc
    47461 tggtttcgac ggtttttggc gtgaactggg cgacgctggc gacaaaactg atggtcgccg
    47521 gaatacgcag atctggcgcg gcatcgagga tcagccgggc ttcaccgccc agtttcagcg
    47581 tgcccgcctg ttcggttggc aggaagaagg tcatatagac gtcgctgaga tcgaccatat
    47641 tcagtacccg accacctgcc gccagcactt cgcctggctc ggcaacccga tactgcacgc
    47701 gtccgtcacg cggggctttc agttcgctgt catcgatatc tgcggcaatg cgccgttcag
    47761 tggcttgcgc ggcttcgacg cgagtttgcg cctgaatgat attggtgcgt gccgcctcta
    47821 tagcggcttt agaagcagaa acctgggctt ttgctgattc cagcgcagct cgggcgctct
    47881 cagcggcggc gcggtcgtca tccagctgtt gcgcagaaat tgccccccgt tgggccagtg
    47941 agcgggaacg cgtatgacgt tttgctacgg agtccagttc tgcctggcgt tgattaacca
    48001 gcgactgtgc ggcacgagtt tcgctttggc gttgctccag caaagcctgc gcggcggcaa
    48061 cggcactttg tgcttctttg atttgcgcga tggcttccat tcgctgttcc tgcaacacgc
    48121 gagtatccat cttcgccagc acttcacctt ctcgaacaaa ctggccttct ttcaccagaa
    48181 tggtgtcgat acgcccggca attttgctgg cgatatccac ttccgtcgct tcaatgcgcc
    48241 cattactgac agcaaagcct tccggcacac ctgccgggcg caacagccac cacgccacga
    48301 tagcggccac cgccagtaac ccgacaaccc accacgccag atggcgctta ctcttatcca
    48361 taatcgaccc gccataatcc ctgtaagcaa acgacgcgtg ttacaactgc cgccgaacga
    48421 cgttcagcgg attcttccat ccgggataag aaggaaacgg caaatacgac cagcgcgcag
    48481 agcattgagc gccaacgtgg aaggcttagt gaaaacgggt agtaatgttg tcatcatcag
    48541 cattcctggc cgtaaatgaa acacgcatac tcataagtgt gatctataaa actggctgac
    48601 aaaacggtat ccatcctgtt ggatagcgtt tcacgcctgt tcagttgcag gaacagagca
    48661 ttccttatta cgttttatca acagtctcaa ccagatagta acattaatat tcatgttgtc
    48721 tatggttcag agctgtaaca ttgtgcgcct tctaatcaaa ggcataagtc catttttgtt
    48781 tttttcatgc tggtaagact tccagggagt ggttatctca ggccccgcac cagggttaat
    48841 ttggcaatta tgcatgctga acattcttcc agcatgttta ctgtcacggg cgttaagacc
    48901 taaaactgtc cccgtttcac ctatgcgttc tctcccacca tttccgttat gtgcaacaac
    48961 ttgatttata cctaacattt gtgagcatgc taatagtgct tcaagtttag gtctgtaatc
    49021 tgtcgaaaca gaaaaataac gattaaagga tcgacaagag atagcccggc tagttttaaa
    49081 ctttttacca ttaattatag tatgatgctt tttattaata attgccgcta attcgaccgg
    49141 atcgagagca ttggtcattt catcaataga gactgttatc ggtcctataa tgtaacgttt
    49201 tcgctgatca tcaaaagtta tcccatgatg atttgccatt attttgtatt tggggtcata
    49261 gaaacataca ggataatctt ttatcccgtc gtaggtatcc tcatcaagtg gtttcatacg
    49321 cgtgaagttc tgcatatagt taccattgca attcgtttca tgattaccag ctaatacatg
    49381 aaaattttca ttgatactca ttatgcgttt taacaaatcg atgataaatt gatcgccaca
    49441 gatattacta aatcgatcgc cggtttggtc tcccagaaac gtacatggcg tcactgcgcc
    49501 tttattaata actaaatatg gctgaatact ttctaaaaca acatctcttc tgttcagaat
    49561 actgattatt gtatta
//
LOCUS       DADXDL010000024        47668 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.024, whole genome shotgun sequence.
ACCESSION   DADXDL010000024 DADXDL010000000
VERSION     DADXDL010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 47668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 47668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..47668
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.024"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..292
                     /locus_tag="IRB70_001686"
     CDS             <1..292
                     /locus_tag="IRB70_001686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type III effector"
                     /protein_id="HBC0631608.1"
                     /translation="EIKELTISRDKSLEEKSTLFDNKRDKWNSQEVQDEVKALNKKIA
                     DCDNEIRSNLNIVQNFRRENQYKANKKISNAMLNILDWFERYPDIVKNITQA"
     gene            complement(429..1094)
                     /gene="yieH"
                     /locus_tag="IRB70_001687"
     CDS             complement(429..1094)
                     /gene="yieH"
                     /locus_tag="IRB70_001687"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphogluconate phosphatase"
                     /protein_id="HBC0631609.1"
                     /translation="MSQIEAVFFDCDGTLVDSEVICSRAYVTMFREFGIHVDLEEIFT
                     RFKGVKLYEIIDIISKEQGVTMIQADAEHVYRAEVARLFDTELEDIAGANELLASINV
                     PMCVVSNGPINKMQHSLGKLKMLHYFPEKLFSGYDIQRWKPDPALMFHAAKAMNVNVE
                     NCILVDDSSAGAQSGIDAGMEVFYFCADPHNKPIVHPKVTTFTELAQLPALWKARGWN
                     ITR"
     gene            1261..2598
                     /gene="adeP"
                     /locus_tag="IRB70_001688"
     CDS             1261..2598
                     /gene="adeP"
                     /locus_tag="IRB70_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeP"
                     /protein_id="HBC0631610.1"
                     /translation="MSQQHTTQASGQGMLERVFKLREHGTTARTEVIAGFTTFLTMVY
                     IVFVNPQILGVAGMDTSAVFVTTCLIAAFGSIMMGLFANLPVALAPAMGLNAFFAFVV
                     VQAMGLPWQVGMGAIFWGAIGLLLLTIFRVRYWMIANIPVSLRVGITSGIGLFIGMMG
                     LKNAGVIVANPETLVSIGNLTSHSVLLGILGFFIIAILASRNIHAAVLVSIVVTTLLG
                     WMLGDVHYNGIVSAPPSVMTVVGHVDLAGSFNLGLAGVIFSFMLVNLFDSSGTLIGVT
                     DKAGLADDKGKFPRMKQALYVDSISSVTGSFIGTSSVTAYIESSSGVSVGGRTGLTAV
                     VVGLLFLLVIFLSPLAGMVPGYAAAGALIYVGVLMTSSLARVNWQDLTESVPAFITAV
                     MMPFSFSITEGIALGFISYCVMKIGTGRLRDLSPCVIIVALLFILKIVFIDAH"
     gene            complement(2652..3218)
                     /gene="yieF"
                     /locus_tag="IRB70_001689"
                     /gene_synonym="chrR"
     CDS             complement(2652..3218)
                     /gene="yieF"
                     /locus_tag="IRB70_001689"
                     /gene_synonym="chrR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I chromate reductase YieF"
                     /protein_id="HBC0631611.1"
                     /translation="MSEKLQVVTLLGSLRKGSFNGMVARTLPKIAPASMEVNALPSIA
                     DIPLYDADVQQEEGFPATVEALAEQIRQADGVVIVTPEYNYSVPGGLKNAIDWLSRLP
                     DQPLAGKPVLIQTSSMGVIGGARCQYHLRQILVFLDAMVMNKPEFMGGVIQNKVDPQT
                     GEVIDQGTLDHLTGQLTAFGEFIQRVKI"
     gene            complement(3240..3989)
                     /locus_tag="IRB70_001690"
     CDS             complement(3240..3989)
                     /locus_tag="IRB70_001690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase superfamily
                     protein"
                     /protein_id="HBC0631612.1"
                     /translation="MATHFARGILTEGHLISVRLPSQCHQEARNIPPHRQSRFLASRG
                     LLAELMFMLYGIGELPEIVTLPKGKPVFSDKNLPSFSISYAGNMVGVALTTEGECGLD
                     MELQRATRGFHSPHAPDNHTFSSNESLWISKQNDPNEARAQLITLRRSVLKLTGDVLN
                     DDPRDLQLLPIAGRLKCAHVNHVEALCDAEDVLVWSVAVTPTIEKLSVWELDGKHGWK
                     SLPDIHSRANNPTSRMMRFAQLSTVKAFSPN"
     gene            complement(4146..5105)
                     /gene="yidZ"
                     /locus_tag="IRB70_001691"
     CDS             complement(4146..5105)
                     /gene="yidZ"
                     /locus_tag="IRB70_001691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator YidZ"
                     /protein_id="HBC0631613.1"
                     /translation="MKKSITTLDLNLLLCLQLLMQERSVTKAAKRMNVTPSAVSKSLA
                     KLRAWFDDPLFVNSPLGLSPTPLMVSMEQNLAEWMQMSNLLLDKPHHQTPRGLKFELA
                     AESPLMMIMLNALSKRIYQRYPQATIKLRNWDYDSLDAITRGEVDIGFSGRESHPRSR
                     ELLSSLPLAIDYEVLFSDVPCVWLRKDHPALHEAWNLDTFLRYPHISICWEQSDTWAL
                     DNVLQELGRERTIAMSMPEFEQSLFMAAQPDNLLLATAPRYCQYYNQLHQLPLVALPL
                     PFDESQQKKLEVPFTLLWHKRNSRNPKIVWLRETIKNLYASMA"
     gene            complement(5080..6255)
                     /gene="mdtL"
                     /locus_tag="IRB70_001692"
     CDS             complement(5080..6255)
                     /gene="mdtL"
                     /locus_tag="IRB70_001692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtL"
                     /protein_id="HBC0631614.1"
                     /translation="MSRFLVCSFALVLLYPAGIDMYLVGLPRIAADLNASEAQLHIAF
                     SVYLAGMAAAMLFAGKVADRSGRKPVTIPGAALFIIASVFCSLAETSTLFLAGRFLQG
                     LGAGCCYVVAFAILRDTLDDRRRAKVLSLLNGITCIIPVLAPVLGHLIMLKFPWQSLF
                     WTMATMGIAVLMLSLFILKETRPAAPAASDKPRENSESLLNRFFLSRVVITTLSVSVI
                     LTFVNTSPVLLMEIMGFERGEYATIMALTAGVSMTVSFSTPFALGIFKPRTLMITSQV
                     LFLAAGITLAVSPSHAVSLFGITLICAGFSVGFGVAMSQALGPFSLRAGVASSTLGIA
                     QVCGSSLWIWLAAVVGIGAWNMLIGILIACSIVSLLLIMFVAPGRPVAAHEEIHHHA"
     gene            complement(6387..7634)
                     /gene="tnaB"
                     /locus_tag="IRB70_001693"
     CDS             complement(6387..7634)
                     /gene="tnaB"
                     /locus_tag="IRB70_001693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity tryptophan permease TnaB"
                     /protein_id="HBC0631615.1"
                     /translation="MTDQAEKKHSAFWGVMVIAGTVIGGGMFALPVDLAGAWFFWGAF
                     ILIIAWFSMLHSGLLLLEANLNYPVGSSFNTITKDLIGNTWNIISGITVAFVLYILTY
                     AYISANGAIISETISMNLGYHANPRIVGICTAIFVASVLWISSLAASRITSLFLGLKI
                     ISFVIVFGSFFFQVDYSILRDATSTTAGTSYFPYIFMALPVCLASFGFHGNIPSLIIC
                     YGKRKDKLIKSVVFGSLLALVIYLFWLYCTMGNIPRESFKAIISSGGNVDSLVKSFLG
                     TKQHGIIEFCLLVFSNLAVASSFFGVTLGLFDYLADLFKIDNSHGGRFKTVLLTFLPP
                     ALLYLIFPNGFIYGIGGAGLCATIWAVIIPAVLAIKARKKFPNQMFTVWGGNLIPAIV
                     ILFGITVILCWFGNVFNVLPKFG"
     gene            complement(7725..9140)
                     /gene="tnaA"
                     /locus_tag="IRB70_001694"
     CDS             complement(7725..9140)
                     /gene="tnaA"
                     /locus_tag="IRB70_001694"
                     /EC_number="4.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709490.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase"
                     /protein_id="HBC0631616.1"
                     /translation="MENFKHLPEPFRIRVIEPVKRTTRAYREEAIIKSGMNPFLLDSE
                     DVFIDLLTDSGTGAVTQSMQAAMMRGDEAYSGSRSYYALAESVKNIFGYQYTIPTHQG
                     RGAEQIYIPVLIKKREQEKGLDRSKMVAFSNYFFDTTQGHSQINGCTVRNVYIKEAFD
                     TGVRYDFKGNFDLEGLERGIEEVGPNNVPYIVATITSNSAGGQPVSLANLKAMYSIAK
                     KYDIPVVMDSARFAENAYFIKQREAEYKDWTIEQITRETYKYADMLAMSAKKDAMVPM
                     GGLLCMKDDSFFDVYTECRTLCVVQEGFPTYGGLEGGAMERLAVGLYDGMNLDWLAYR
                     IAQVQYLVDGLEEIGVVCQQAGGHAAFVDAGKLLPHIPADQFPAQALACELYKVAGIR
                     AVEIGSFLLGRDPKTGKQLPCPAELLRLTIPRATYTQTHMDFIIEAFKHVKENAANIK
                     GLTFTYEPKVLRHFTAKLKEV"
     gene            complement(9361..9435)
                     /gene="tnaC"
                     /locus_tag="IRB70_001695"
     CDS             complement(9361..9435)
                     /gene="tnaC"
                     /locus_tag="IRB70_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophanase leader peptide"
                     /protein_id="HBC0631617.1"
                     /translation="MNILHICVTSKWFNIDNKIVDHRP"
     gene            complement(9678..11042)
                     /gene="mnmE"
                     /locus_tag="IRB70_001696"
     CDS             complement(9678..11042)
                     /gene="mnmE"
                     /locus_tag="IRB70_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBC0631618.1"
                     /translation="MSDNDTIVAQATPPGRGGVGILRISGLKAREVAETVLGKLPKPR
                     YADYLPFKDADGSVLDQGIALWFPGPNSFTGEDVLELQGHGGPVILDLLLKRILTIPG
                     LRIARPGEFSERAFLNDKLDLAQAEAIADLIDASSEQAARSALNSLQGAFSARVNHLV
                     EALTHLRIYVEAAIDFPDEEIDFLSDGKIEAQLNDVIADLDAVRAEARQGSLLREGMK
                     VVIAGRPNAGKSSLLNALAGREAAIVTDIAGTTRDVLREHIHIDGMPLHIIDTAGLRE
                     ASDEVERIGIERAWQEIEQADRVLFMVDGTTTDAVDPAEIWPEFIARLPAKLPITVVR
                     NKADITGETLGMSEVNGHALIRLSARTGEGVDVLRNHLKQSMGFDTNMEGGFLARRRH
                     LQALEQAAEHLQQGKAQLLGAWAGELLAEELRLAQQNLSEITGEFTSDDLLGRIFSSF
                     CIGK"
     gene            complement(11151..12797)
                     /gene="yidC"
                     /locus_tag="IRB70_001697"
     CDS             complement(11151..12797)
                     /gene="yidC"
                     /locus_tag="IRB70_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBC0631619.1"
                     /translation="MDSQRNLLVIALLFVSFMIWQAWEQDKNPQPQAQQTTQTTTTAA
                     GSAADQGVPASGQGKLISVKTDVLDLTINTRGGDVEQALLPAYPKELNSTQPFQLLET
                     SPQFIYQAQSGLTGRDGPDNPANGPRPLYNVEKDAYVLAEGQNELQVPMTYTDAAGNT
                     FTKTFVLKRGDYAVNVNYNVQNAGEKPLEISTFGQLKQSITLPPHLDTGSSNFALHTF
                     RGAAYSTPDEKYEKYKFDTIADNENLNISSKGGWVAMLQQYFATAWIPHNDGTNNFYT
                     ANLGNGIAAIGYKSQPVLVQPGQTGAMNSTLWVGPEIQDKMAAVAPHLDLTVDYGWLW
                     FISQPLFKLLKWIHSFVGNWGFSIIIITFIVRGIMYPLTKAQYTSMAKMRMLQPKIQA
                     MRERLGDDKQRISQEMMALYKAEKVNPLGGCFPLLIQMPIFLALYYMLMGSVELRQAP
                     FALWIHDLSAQDPYYILPILMGVTMFFIQKMSPTTVTDPMQQKIMTFMPVIFTVFFLW
                     FPSGLVLYYIVSNLVTIIQQQLIYRGLEKRGLHSREKKKS"
     gene            complement(12800..13057)
                     /gene="yidD"
                     /locus_tag="IRB70_001698"
     CDS             complement(12800..13057)
                     /gene="yidD"
                     /locus_tag="IRB70_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBC0631620.1"
                     /translation="MAPPLSPGSRVLIALIRVYQRLISPLLGPHCRFTPTCSSYGIEA
                     LRRFGVIKGSWLTVKRVLKCHPLHPGGDDPVPPGPFDTREH"
     gene            complement(13021..13380)
                     /gene="rnpA"
                     /locus_tag="IRB70_001699"
     CDS             complement(13021..13380)
                     /gene="rnpA"
                     /locus_tag="IRB70_001699"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014172301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBC0631621.1"
                     /translation="MVKLAFPRELRLLTPSQFTFVFQQPQRAGTPQITILGRLNSLGH
                     PRIGLTVAKKNVRRAHERNRIKRLTRESFRLRQHELPAMDFVVVAKKGVADLDNRALS
                     EALEKLWRRHCRLARGS"
     gene            complement(13397..13537)
                     /gene="rpmH"
                     /locus_tag="IRB70_001700"
     CDS             complement(13397..13537)
                     /gene="rpmH"
                     /locus_tag="IRB70_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBC0631622.1"
                     /translation="MKRTFQPSVLKRNRSHGFRARMATKNGRQVLARRRAKGRARLTV
                     SK"
     gene            complement(13767..13847)
                     /locus_tag="IRB70_001701"
                     /pseudo
     CDS             complement(13767..13847)
                     /locus_tag="IRB70_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518826.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            14144..15547
                     /gene="dnaA"
                     /locus_tag="IRB70_001702"
     CDS             14144..15547
                     /gene="dnaA"
                     /locus_tag="IRB70_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBC0631623.1"
                     /translation="MSLSLWQQCLARLQDELPATEFSMWIRPLQAELSDNTLALYAPN
                     RFVLDWVRDKYLNNINGLLTSFCGADAPQLRFEVGTKPVTQTPQAAVTSNVAAPAQVA
                     QTQPQRAAPSTRSGWDNVPAPAEPTYRSNVNVKHTFDNFVEGKSNQLARAAARQVADN
                     PGGAYNPLFLYGGTGLGKTHLLHAVGNGIMARKPNAKVVYMHSERFVQDMVKALQNNA
                     IEEFKRYYRSVDALLIDDIQFFANKERSQEEFFHTFNALLEGNQQIILTSDRYPKEIN
                     GVEDRLKSRFGWGLTVAIEPPELETRVAILMKKADENDIRLPGEVAFFIAKRLRSNVR
                     ELEGALNRVIANANFTGRAITIDFVREALRDLLALQEKLVTIDNIQKTVAEYYKIKVA
                     DLLSKRRSRSVARPRQMAMALAKELTNHSLPEIGDAFGGRDHTTVLHACRKIEQLREE
                     SHDIKEDFSNLIRTLSS"
     gene            15552..16652
                     /gene="dnaN"
                     /locus_tag="IRB70_001703"
     CDS             15552..16652
                     /gene="dnaN"
                     /locus_tag="IRB70_001703"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006177590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBC0631624.1"
                     /translation="MKFTVEREHLLKPLQQVSGPLGGRPTLPILGNLLLQVADGTLSL
                     TGTDLEMEMVARVALVQPHEPGATTVPARKFFDICRGLPEGAEIAVQLEGERMLVRSG
                     RSRFSLSTLPAADFPNLDDWQSEVEFTLPQATMKRLIEATQFSMAHQDVRYYLNGMLF
                     ETEGEELRTVATDGHRLAVCSMPIGQSLPSHSVIVPRKGVIELMRMLDGGDNPLRVQI
                     GSNNIRAHVGDFIFTSKLVDGRFPDYRRVLPKNPDKHLEAGCDLLKQAFARAAILSNE
                     KFRGVRLYVSENQLKITANNPEQEEAEEILDVTYSGAEMEIGFNVSYVLDVLNALKCE
                     NVRMMLTDSVSSVQIEDAASQSAAYVVMPMRL"
     gene            16652..17725
                     /gene="recF"
                     /locus_tag="IRB70_001704"
     CDS             16652..17725
                     /gene="recF"
                     /locus_tag="IRB70_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBC0631625.1"
                     /translation="MSLTRLLIRDFRNIETADLALSPGFNFLVGANGSGKTSVLEAIY
                     TLGHGRAFRSLQIGRVIRHEQEAFVLHGRLQGEERETAIGLTKDKQGDSKVRIDGTDG
                     HKVAELAHLMPMQLITPEGFTLLNGGPKYRRAFLDWGCFHNEPGFFTAWSNLKRLLKQ
                     RNAALRQVTRYEQLRPWDKELIPLAEQISTWRAEYSAGIAADMADTCKQFLPEFSLTF
                     SFQRGWEKETEYAEVLERNFERDRQLTYTAHGPHKADLRIRADGAPVEDTLSRGQLKL
                     LMCALRLAQGEFLTRESGRRCLYLIDDFASELDDERRGLLASRLKATQSQVFVSAISA
                     EHVIDMSDENSKMFTVEKGKITD"
     gene            17754..20168
                     /gene="gyrB"
                     /locus_tag="IRB70_001705"
     CDS             17754..20168
                     /gene="gyrB"
                     /locus_tag="IRB70_001705"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBC0631626.1"
                     /translation="MSNSYDSSSIKVLKGLDAVRKRPGMYIGDTDDGTGLHHMVFEVV
                     DNAIDEALAGHCKEIIVTIHADNSVSVQDDGRGIPTGIHPEEGVSAAEVIMTVLHAGG
                     KFDDNSYKVSGGLHGVGVSVVNALSQKLELVIQREGKIHRQIYEHGVPQAPLAVTGET
                     EKTGTMVRFWPSLETFTNVTEFEYEILAKRLRELSFLNSGVSIRLRDKRDGKEDHFHY
                     EGGIKAFVEYLNKNKTPIHPNIFYFSTEKDGIGVEVALQWNDGFQENIYCFTNNIPQR
                     DGGTHLAGFRAAMTRTLNAYMDKEGYSKKAKVSATGDDAREGLIAVVSVKVPDPKFSS
                     QTKDKLVSSEVKSAVEQQMNELLAEYLLENPTDAKIVVGKIIDAARAREAARRAREMT
                     RRKGALDLAGLPGKLADCQERDPALSELYLVEGDSAGGSAKQGRNRKNQAILPLKGKI
                     LNVEKARFDKMLSSQEVATLITALGCGIGRDEYNPDKLRYHNIIIMTDADVDGSHIRT
                     LLLTFFYRQMPEIVERGHVYIAQPPLYKVKKGKQEQYIKDDEAMDQYQISIALDGATL
                     HTNASAPALAGEALEKLVSEYNATQKMINRMERRYPKAMLKELIYQPTLTETDLSDEQ
                     TVTRWVNALVSELNDKEQHGSQWKFDVHTNADQNLFEPIVRVRTHGVDTDYPLDHEFI
                     TGGEYRRICTLGEKLRGLLEEDAFIERGERRQPVASFEQALDWLVKESRRGLSIQRYK
                     GLGEMNPEQLWETTMDPESRRMLRVTVKDAIAADQLFTTLMGDAVEPRRAFIEENALK
                     AANIDI"
     gene            20312..20710
                     /locus_tag="IRB70_001706"
     CDS             20312..20710
                     /locus_tag="IRB70_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312660.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidB family protein"
                     /protein_id="HBC0631627.1"
                     /translation="MGLFDDVVGAFLKGDAGKYQAILSWVEEQGGIQVLLEKLQSGGL
                     GAILSTWLSNQQGNQPVSGEQLESALGTNAVSDLGQKLGVDTSTASSLLAEQLPKIID
                     ALSPQGEVSAQANNDLLSAGMELLKGKLFR"
     gene            20825..21637
                     /gene="yidA"
                     /locus_tag="IRB70_001707"
     CDS             20825..21637
                     /gene="yidA"
                     /locus_tag="IRB70_001707"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBC0631628.1"
                     /translation="MAIKLIAIDMDGTLLLPDHTISPAVKNAIAAARARGVNVVLTTG
                     RPYAGVHNYLKELHMEQPGDYCITYNGALVQKAADGSTVAQTALSYDDYRFLEKLSRE
                     VGSHFHALDRTTLYTANRDISYYTVHESFVATIPLVFCEAEKMDPNTQFLKVMMIDEP
                     AILDQAIARIPQEVKEKYTVLKSAPYFLEILDKRVNKGTGVKSLADVLGIKPEEIMAI
                     GDQENDIAMIEYAGVGVAMDNAIPSVKEVANFVTKSNLEDGVAFAIEKYVLN"
     gene            complement(21681..22337)
                     /locus_tag="IRB70_001708"
     CDS             complement(21681..22337)
                     /locus_tag="IRB70_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010377884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631629.1"
                     /translation="MKLNFKGFFKAAGLCSLAFALTGCITWGLVSNTASRPHAEQWRS
                     DTIKGLSLAEDSNGTKGYVFVGESLDYLLTTGGDEVVKMLNDPAIHGERITVSDNAKF
                     ILSSSDTNFSGSITLYYDWDNEEDKALATQYGFICNTQRCTWALDGLKGSIHQKNKKA
                     DYSNVMVFHQPFTVGFYKYKATDGVPRGLANALLPVTLTLDIVTSPLQFLILCTTRNC
                     "
     gene            22615..23304
                     /gene="dgoR"
                     /locus_tag="IRB70_001709"
     CDS             22615..23304
                     /gene="dgoR"
                     /locus_tag="IRB70_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate utilization transcriptional
                     regulator DgoR"
                     /protein_id="HBC0631630.1"
                     /translation="MTLNKTDRIVITLGKQIVHGKYVPGSPLPAEAELCEEFATSRNI
                     IREVFRSLMAKRLIEMKRYRGAFVAPRNQWNYLDTDVLQWVLENDYDPRLISAMSEVR
                     NLVEPAIARWAAERATSSDLAQIESALNEMIANNQDREAFNEADIRYHEAVLQSVHNP
                     VLQQLSIAISSLQRAVFERTWMGDEANMPQTLQEHKALFDAIRHQDGDAAEQAALTMI
                     ASSTRRLKEIT"
     gene            23301..24179
                     /gene="dgoK"
                     /locus_tag="IRB70_001710"
     CDS             23301..24179
                     /gene="dgoK"
                     /locus_tag="IRB70_001710"
                     /EC_number="2.7.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HBC0631631.1"
                     /translation="MTARYIAIDWGSTNLRAWLYQGDHCLESRQSEAGVTRLNGKSPA
                     AVLAEVTTDWREENTPVVMAGMVGSNVGWKVAPYLSVPARFSSIGEQLTSVGDNIWII
                     PGLCVSHDDNHNVMRGEETQLIGARALAPSSLYVMPGTHCKWVQADSQQINDFRTVMT
                     GELHHLLLNHSLIGAGLPPQENSADAFAAGLERGLNAPAILPQLFEVRASHVLGTLPR
                     EQVSEFLSGLLIGAEVASMRDYVTHQHAITLVAGTSLTARYQQAFQAMGCDVAAVAGD
                     TAFQAGIRSIAHAVAN"
     gene            24163..24780
                     /gene="dgoA"
                     /locus_tag="IRB70_001711"
     CDS             24163..24780
                     /gene="dgoA"
                     /locus_tag="IRB70_001711"
                     /EC_number="4.1.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HBC0631632.1"
                     /translation="MQWQTKLPLIAILRGITPDEALAHVGAVIDAGFDAVEIPLNSPQ
                     WEKSIPAIVDAYGDKALIGAGTVLKPEQVDTLARMGCQLIVTPNIHSEVIRRAVGYGM
                     TVCPGCATATEAFTAIDAGAQALKIFPSSAFGPQYIKALKAVLPQDIPVFAVGGVTPE
                     NLAQWIDAGCAGAGLGSDLYRAGQSVERTAQQAAAFVKAYREAVQ"
     gene            24777..25925
                     /gene="dgoD"
                     /locus_tag="IRB70_001712"
     CDS             24777..25925
                     /gene="dgoD"
                     /locus_tag="IRB70_001712"
                     /EC_number="4.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020077623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactonate dehydratase"
                     /protein_id="HBC0631633.1"
                     /translation="MKITNITTYRLPPRWMFLKIETDEGVVGWGEPVIEGRARTVEAA
                     VHELSDYLIGQDPSRINDLWQVMYRAGFYRGGPILMSAIAGIDQALWDIKGKVLNAPV
                     WQLMGGLVRDKIKAYSWVGGDRPADVIDGIKTLREIGFDTFKLNGCEELGLIDNSRAV
                     DAAVNTVAQIREAFGNQIEFGLDFHGRVSAPMAKVLIKELEPYRPLFIEEPVLAEQAE
                     YYPKLAAQTHIPLAAGERMFSRFDFKRVLEAGGISILQPDLSHAGGITECYKIAGMAE
                     AYDVTLAPHCPLGPIALAACLHIDFVSYNAVLQEQSMGIHYNKGAELLDFVKNKEDFS
                     MVGGFFKPLTKPGLGVEIDEAKVIEFSKNAPDWRNPLWRHEDNSVAEW"
     gene            26000..27337
                     /locus_tag="IRB70_001713"
     CDS             26000..27337
                     /locus_tag="IRB70_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0631634.1"
                     /translation="MVSGFAMPKIWRKLAMDIPVNAAKPGRRRYLTLVMIFITVVICY
                     VDRANLAVASAHIQEEFGITKAEMGYVFSAFAWLYTLCQIPGGWFLDRVGSRVTYFIA
                     IFGWSVATLFQGFATGLMSLIGLRAITGIFEAPAFPTNNRMVTSWFPEHERASAVGFY
                     TSGQFVGLAFLTPLLIWIQEMLSWHWVFIVTGGIGIIWSLIWFKVYQPPRLTKGISKA
                     ELDYIRDGGGLVDGDAPVKKEARQPLTAKDWKLVFHRKLIGVYLGQFAVASTLWFFLT
                     WFPNYLTQEKGITALKAGFMTTVPFLAAFVGVLLSGWVADLLVRKGFSLGFARKTPII
                     CGLLISTCIMGANYTNDPMMIMCLMALAFFGNGFASITWSLVSSLAPMRLIGLTGGVF
                     NFAGGLGGITVPLVVGYLAQGYGFAPALVYISAVALIGALSYILLVGDVKRVG"
     gene            complement(27334..28398)
                     /gene="cbrA"
                     /locus_tag="IRB70_001714"
     CDS             complement(27334..28398)
                     /gene="cbrA"
                     /locus_tag="IRB70_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709508.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin M resistance protein"
                     /protein_id="HBC0631635.1"
                     /translation="MEHFDVAIIGLGPAGSALARKLAGKMQVIALDKKHQCGTEGFSK
                     PCGGLLAPDAQRSFIRDGLTLPVDVIANPQIFSVKTVDVAASLTRNYQRSYININRHA
                     FDLWMKSLIPASVEVYHDSLCRKIWREDDKWHVIFRADGWEQHISARYLVGADGANSM
                     VRRHLYPDHQIRKYVAIQQWFAEKHPVPFYSCIFDNAITDCYSWSISKDGYFIFGGAY
                     PMKDGQTRFTTLKEKMNAFQFQFGKAVKSEKCTVLFPSRWQDFVCGKDNAFLIGEAAG
                     FISASSLEGISYALDSAEILRSVLLKQPEKINAAYWRATRKLRLKLYGKIVKSRCLTA
                     PALRKWIMRSGVAHIPQLKD"
     gene            28499..29713
                     /locus_tag="IRB70_001715"
     CDS             28499..29713
                     /locus_tag="IRB70_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312656.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3748 domain-containing protein"
                     /protein_id="HBC0631636.1"
                     /translation="MKQITFAPRNHLLTNTNTWTPDSQWLVFDVRPSGASFTGETIER
                     VNIHTGEVEVIYRASQGAYVGVVTVHPKSEKYVFIHGPENPDETWYYDFHHRRGVIVE
                     GGKVSNLDAMDITAPYTPGALRGGSHVHVFSPNGERVSFTYNDHVMHELDPVLDLRNV
                     GVAAPFGPVNVQKQHPREYSGSHWCVLVSKTTPTPQPGSDEINRAYEEGWVGNHALAF
                     IGDTLSAKGEKVPELFIVELPQDEAGWKAAGDAPLSGTETTLPAPPRGVVQRRLTFTH
                     HRAYPGLVNVPRHWVRCNPQGTQIAFLMRDDNGIVQLWLISPQGGEPRQLTHNKTDIQ
                     SAFNWHPSGEWLGFVLDNRIACAHAQSGEVEYLTENHANPPSADAVVFSPDGQWLAWM
                     EGGQLWITETDR"
     gene            complement(29715..30047)
                     /locus_tag="IRB70_001716"
     CDS             complement(29715..30047)
                     /locus_tag="IRB70_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418143.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YceK/YidQ family lipoprotein"
                     /protein_id="HBC0631637.1"
                     /translation="MIRNVLLAFMICSGMTLLGGCSSVMSHTGGKEGTYPGTRASATM
                     IGDDETNWGTKSLAILDMPFTAVMDTLLLPWDVFRKDSSVRSRVEKSEANAQATNAVI
                     PPARMPDN"
     misc_feature    30287..30359
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01832"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ROSE (Repression Of Heat Shock gene Expression)
                     occurs in the 5'-region of heat shock genes and acts as an
                     RNA thermometer to modulate expression; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF01832"
     gene            30353..30766
                     /gene="ibpA"
                     /locus_tag="IRB70_001717"
     CDS             30353..30766
                     /gene="ibpA"
                     /locus_tag="IRB70_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpA"
                     /protein_id="HBC0631638.1"
                     /translation="MRNFDLSPLYRSAIGFDRLFNHLENNQSQSNGGYPPYNVELVDE
                     NHYRIAIAVAGFAESELEITAQDNLLVVKGAHADEQKERTYLYQGIAERNFERKFQLA
                     ENIHVRGANLVNGLLYIDLERVIPEAKKPRRIEIN"
     gene            30878..31306
                     /gene="ibpB"
                     /locus_tag="IRB70_001718"
     CDS             30878..31306
                     /gene="ibpB"
                     /locus_tag="IRB70_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709512.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat shock chaperone IbpB"
                     /protein_id="HBC0631639.1"
                     /translation="MRNFDLSPLMRQWIGFDKLANALQNAGESQSFPPYNIEKSDDNH
                     YRITLALAGFRQEDLEIQLEGTRLSVKGTPEQPKEEKKWLHQGLMNQPFSLSFTLAEN
                     MEVSGATFVNGLLHIDLIRNEPEPIAAQRIAISERPALNS"
     gene            31502..33163
                     /locus_tag="IRB70_001719"
     CDS             31502..33163
                     /locus_tag="IRB70_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative transporter"
                     /protein_id="HBC0631640.1"
                     /translation="MSDIALTVSILALVAVVGLFIGNVKFRGIGLGIGGVLFGGIIVG
                     HFVSQAGMTLSSDMLHVIQEFGLILFVYTIGIQVGPGFFASLRVSGLRLNLFAVLIVI
                     IGGLVTAILHKLFDIPLPVVLGIFSGAVTNTPALGAGQQILRDLGTPMEMVDQMGMSY
                     AMAYPFGICGILFTMWMLRVIFRVNVETEAQQHESSRTNGGALIRTINIRVENPNLHD
                     LAIKDVPILNGDKIICSRLKREETLKVPSPDTIIQLGDLLHLVGQPADLHNAQLVIGQ
                     EVDTSLSTKGTDLRVERVVVTNENVLGKRIRDLHFKERYDVVISRLNRAGVELVASGD
                     ISLQFGDILNLVGRPSAIDAVANVLGNAQQKLQQVQMLPVFIGIGLGVLLGSIPVFVP
                     GFPAALKLGLAGGPLIMALILGRIGSIGKLYWFMPPSANLALRELGIVLFLSVVGLKS
                     GGDFVNTLVNGEGLSWIGYGALITAVPLITVGILARMLAKMNYLTMCGMLAGSMTDPP
                     ALAFANNLHPTSGAAALSYATVYPLVMFLRIITPQLLAVLFWSIG"
     gene            complement(33160..33876)
                     /locus_tag="IRB70_001720"
     CDS             complement(33160..33876)
                     /locus_tag="IRB70_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBC0631641.1"
                     /translation="MIYKSIAERLRIRLNSADFTLNSLLPGEKKLAEEFAVSRMTIRK
                     AIDLLVAWGLVVRRHGSGTYLVRKDVLHQTASLTGLVEVLKRQGKTVTSQVLIFEIMP
                     APPAIASQLRIQINEQIYFSRRVRFVEGKPLMLEDSYMPVKLFRNLSLQHLEGSKFEY
                     IEQECGILIGGNYESLTPVLADRLLARQMKVAEHTPLLRITSLSYSESGEFLNYSVMF
                     RNASEYQVEYHLRRLHPEKS"
     gene            34172..35788
                     /locus_tag="IRB70_001721"
     CDS             34172..35788
                     /locus_tag="IRB70_001721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312650.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBC0631642.1"
                     /translation="MLSQIQRFGGAMFTPVLLFPFAGIVVGLAILLQNPMFVGESLTD
                     PNSLFAQIVHIIEEGGWTVFRNMPLIFAVGLPIGLAKQAQGRACLAVMVSFLTWNYFI
                     NAMGMTWGSYFGVDFTQDAVAGSGLTMMAGIKTLDTSIIGAIIISGIVTALHNRLFDK
                     KLPVFLGIFQGTSYVVIIAFLVMIPCAWLTLLGWPKVQMGIESLQAFLRSAGALGVWV
                     YTFLERILIPTGLHHFIYGPFIFGPAAVEGGIQMYWAQHLQEFSLSAEPLKSLFPEGG
                     FALHGNSKIFGAVGISLAMYFTAAPENRVKVAGLLIPATLTAMLVGITEPLEFTFLFI
                     SPLLFAVHAVLAASMSTVMYLFGVVGNMGGGLIDQVLPQNWIPMFSNHADMMLTQIAI
                     GLCFTLLYFVVFRTLILQFNMCTPGREDAEVKLYSKAEYKASRGQTTAAEPKKELDQA
                     AGILQALGGVGNISSINNCATRLRIALHDMSQTLDDEVFKKLGAHGVFRSGDAIQVII
                     GLHVSQLREQLDSLINSHQSAENVAITEAV"
     gene            35788..37110
                     /locus_tag="IRB70_001722"
     CDS             35788..37110
                     /locus_tag="IRB70_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312649.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-alpha-glucosidase"
                     /protein_id="HBC0631643.1"
                     /translation="MTKFSVVVAGGGSTFTPGIVLMLLANQDRFPLRALKFYDNDGAR
                     QEVIAEACKVILKEKAPDIAFSYTTDPEVAFSDVDFVMAHIRVGKYPMRELDEKIPLR
                     HGVVGQETCGPGGIAYGMRSIGGVLELVDYMEKYSPNAWMLNYSNPAAIVAEATRRLR
                     PNAKILNICDMPIGIESRMAQIVGLQDRKQMRVRYYGLNHFGWWTSIEDLQGNDLMPQ
                     LRQYVSKHGYVPPQQDTHTEASWNDTYAKARDVQALDPDTLPNTYLKYYLFPDYVVQH
                     SNPEHTRANEVMEHREKQVFDACRAITAAGNSAAGKLEIDEHASYIVDLAAAIAFNTQ
                     ERMLLIVPNNGAIHNFDDEAMVEIPCLVGHNGPEPLVVGDIPQFQKGLMSQQVTVEKL
                     VVDAWEQRSYQHLWQAITLSKTVPSASVAKAILDELLEANKAYWPELR"
     gene            complement(37107..38000)
                     /locus_tag="IRB70_001723"
     CDS             complement(37107..38000)
                     /locus_tag="IRB70_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418136.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBC0631644.1"
                     /translation="MNGKLQSSDVKNETPYNIPLLINENVISSGISLISLWHTYADEH
                     YRVIWPRDKKKPLIANSWVAVYTVQGCGKIILKNGEQITLHGNCIIFLKPMDIHSYHC
                     EGLVWEQYWMEFTPTSMMDIPVGQQSVIYNGEVYNQELTEVAELITSPEAIKNNLAVA
                     FLTKIIYQWICLMHAVGKKDPQRRQIEKLIATLHASLQQRWSVADMAATIPCSEAWLR
                     RLFLRYTGKTPKEYYLDARLDLALSLLKQQGNSVGEVADTLNFFDSFHFSKAFKNKFG
                     YAPSAVLKNTDQHPTDASPHN"
     gene            38167..39882
                     /locus_tag="IRB70_001724"
     CDS             38167..39882
                     /locus_tag="IRB70_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="solute:sodium symporter family transporter"
                     /protein_id="HBC0631645.1"
                     /translation="MNSLQILSFVGFTLLVAIITWWKVRKTDTGSQQGYFLAGRSLKA
                     PVIAASLMLTNLSTEQLVGLSGQAYKSGMSVMGWEVTSAVTLIFLALIFLPRYLKRGI
                     ATIPDFLEERYDKTTRIIIDFCFLIATGVCFLPIVLYSGALALNSLFHVGESLQISHG
                     AAIWLLVILLGLAGILYAVIGGLRAMAVADSINGIGLVIGGLMVPIFGLIAMGKGSFM
                     QGIEQLTTVHAEKLNSVGGPTDPLPIGAAFTGLILVNTFYWCTNQGIVQRTLASKSLA
                     EGQKGALLTAVLKMLDPLVLVLPGLIAFHLYQDLPKADMAYPTLVNNVLPVPLVGFFG
                     AVLFGAVISTFNGFLNSASTLFSMGIYRRIINQNAEPQQLVTVGRKFGFFIAIVSVLV
                     APWIANAPQGLYSWMKQLNGIYNVPLVTIIIMGFFFPRIPALAAKVAMGIGIISYITI
                     NYLVKFDFHFLYVLACTFCINVVVMLVIGFIKPRATPFTFKDAFAVDMKPWKNVKIAS
                     IGILFAMIGVYAGLAEFGGYGTRWLAMISYFIAAVVIVYLIFDSWRHRHDPAVTFTPD
                     AKDSL"
     gene            39879..41372
                     /locus_tag="IRB70_001725"
     CDS             39879..41372
                     /locus_tag="IRB70_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBC0631646.1"
                     /translation="MKRPNFLFIMTDTQATNMVGCYSGKPLNTQNIDSLAAESIRFNS
                     AYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKNISTMGRYFKDAGYHTCYIGKWH
                     LDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
                     TWAHRISNRAVDFLQQPARAEEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKS
                     QDDLANKPEHHRLWAQAMPSPVGDDGLYHHPLYFACNDFVDDQIGRVINALTPEQREN
                     TWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERRQVDTPVSHIDLLPT
                     MMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLV
                     LNLFTSDELYDRRNDSNEMHNLIDDIRFADVRRKMHDALLDYMDKIRDPFRSYQWSLR
                     PWRKDARPRWMGAFRPRPQDGYSPVVRDYDTGLPTQGVKVEEKKQKF"
     gene            41432..41779
                     /locus_tag="IRB70_001726"
     CDS             41432..41779
                     /locus_tag="IRB70_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YidH family protein"
                     /protein_id="HBC0631647.1"
                     /translation="MKISRLGEAPDYRFSLANERTFLAWIRTALGFLAAGVGLDQLAP
                     DFATPVIRELLALLLCLFSGGLAMYGYLRWLRNEKAMRLKEDLPYTNSLLIISLILMV
                     VAVIVMGLVLYAG"
     gene            41769..42131
                     /locus_tag="IRB70_001727"
     CDS             41769..42131
                     /locus_tag="IRB70_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF202 domain-containing protein"
                     /protein_id="HBC0631648.1"
                     /translation="MPDSRKARRIADPGLQPERTSLAWFRTMLGYGALMALAIKHNWH
                     QAGMLFWISIGILAIVALILWHYTRNRNLMDVTNSDFSQFHVVRDKFLISLAVLSLAI
                     LFAVTHIHQLIVFIERVA"
     gene            42128..42625
                     /locus_tag="IRB70_001728"
     CDS             42128..42625
                     /locus_tag="IRB70_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBC0631649.1"
                     /translation="MTGSQVIDAEEDRHKLVVEYKDALQPADFYHNFKQRGIRSVQLI
                     PHLEFDDRGDLTAASVTAELWGKFLIALFECWVRADISRISIELFDATLQKWCGSENP
                     QPRRGCQACDWHRLCPHAREETPDNVLCAGYQAFYSYSAPHMRVMRDLIKQHRSPMEL
                     MTMLR"
     gene            complement(42633..43817)
                     /gene="emrD"
                     /locus_tag="IRB70_001729"
     CDS             complement(42633..43817)
                     /gene="emrD"
                     /locus_tag="IRB70_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418129.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EmrD"
                     /protein_id="HBC0631650.1"
                     /translation="MKRHRNVNLLLMLVLLVAVGQMAQTIYIPAIADMARDLNVREGA
                     VQSVMGAYLLTYGVSQLFYGPISDRVGRRPVILVGMSIFMLATLVAVTTSSLTVLIAA
                     SAMQGMGTGVGGVMARTLPRDLYERTQLRHANSLLNMGILVSPLLAPLIGGLLDTMWN
                     WRACYLFLLVLCAGVTFSMARWMPETRPVDAPRTRLLTSYKTLFGNSGFNCYLLMLIG
                     GLAGIAAFEACSGVLMGAVLGLSSMTVSILFILPIPAAFFGAWFAGRPNKRFSTLMWQ
                     SVICCLLAGLLMWIPDWFGVMNVWTLLVPAALFFFGAGMLFPLATSGAMEPFPFLAGT
                     AGALVGGLQNIGSGVLASLSAMLPQTGQGSLGLLMTLMGLLIVLCWLPLATRMSHQGQ
                     PV"
     gene            complement(44097..44186)
                     /gene="tisB"
                     /locus_tag="IRB70_001730"
     CDS             complement(44097..44186)
                     /gene="tisB"
                     /locus_tag="IRB70_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin TisB"
                     /protein_id="HBC0631651.1"
                     /translation="MSLVDIAILILKLIVAALQLLDTVLKYLK"
     gene            44751..44849
                     /gene="ivbL"
                     /locus_tag="IRB70_001731"
     CDS             44751..44849
                     /gene="ivbL"
                     /locus_tag="IRB70_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ilvB operon leader peptide IvbL"
                     /protein_id="HBC0631652.1"
                     /translation="MTTSMLNAKLLPTAPSAAVVVVRVVVVVGNAP"
     gene            44955..46643
                     /gene="ilvB"
                     /locus_tag="IRB70_001732"
     CDS             44955..46643
                     /gene="ilvB"
                     /locus_tag="IRB70_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase large subunit"
                     /protein_id="HBC0631653.1"
                     /translation="MASSGTTSTRKRFTGAEFIVHFLEQQGIKIVTGIPGGSILPVYD
                     ALSQSTQIRHILARHEQGAGFIAQGMARTDGKPAVCMACSGPGATNLVTAIADARLDS
                     IPLICITGQVPASMIGTDAFQEVDTYGISIPITKHNYLVRHIEELPQVMSDAFRIAQS
                     GRPGPVWIDIPKDVQTAVFEIEAQPAMAEKAAAPAFSEESIRDAAAMINAAKRPVLYL
                     GGGVINAPARVRELAEKAQLPTTMTLMALGMLPKANPLSLGMLGMHGVRSTNYILQEA
                     DLLIVLGARFDDRAIGKTEQFCPNAKIIHVDIDRAELGKIKQPHVAIQADVDDVLAQL
                     IPLVEAQPRAEWHQLVADLQREFPCPIPKACDPLTHYGLINAVAACVDDSAIITTDVG
                     QHQMWTAQAYPLNRPRQWLTSGGLGTMGFGLPAAIGAALANPDRKVLCFSGDGSLMMN
                     IQEMATASENQLDVKIILMNNEALGLVHQQQSLFYKQGVFAATYPGKINFMQIAAGFG
                     LETCDLNNETDPQAALQEIINRPGPALIHVRIDAEEKVYPMVPPGAANTEMVGE"
     gene            46647..46937
                     /gene="ilvN"
                     /locus_tag="IRB70_001733"
     CDS             46647..46937
                     /gene="ilvN"
                     /locus_tag="IRB70_001733"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
                     /protein_id="HBC0631654.1"
                     /translation="MQNTTHDNVILELTVRNHPGVMTHVCGLFARRAFNVEGILCLPI
                     QDSDKSHIWLLVNDDQRLEQMISQIDKLEDVVKVQRNQSDPTMFNKIAVFFQ"
     gene            47200..>47668
                     /locus_tag="IRB70_001734"
     CDS             47200..>47668
                     /locus_tag="IRB70_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001626294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631655.1"
                     /translation="MASPIISGTMMSNPCPSTFLDKNINIAAELDITKNEKKYSPGSN
                     FAKWMLQEIKRLILNIMSGSRSVNTEILDYFHPMPGTENNGNRTWMAATGEDEYIEIK
                     QTGDKSFNITLVGRDKRLRKETPYSGVAVATIIKSLSEKTAALETHSADTVLRK"
BASE COUNT        11539 a        12067 c        12555 g        11507 t
ORIGIN      
        1 agaaattaaa gagttaacca taagtcggga taaatcatta gaggagaaaa gtactttatt
       61 tgataacaaa agggacaagt ggaatagtca agaagtacag gatgaagtaa aggcattaaa
      121 taagaagatt gctgactgtg acaatgagat acgttctaat cttaatattg ttcaaaattt
      181 tagacgcgag aatcaatata aagctaataa aaaaatcagt aacgcgatgc ttaatattct
      241 ggattggttc gaacggtatc ccgatattgt gaaaaatata acccaggctt aaccatacag
      301 agggtgagcg actggacgat taacgacata aattatttac agggaataga cgcttactca
      361 tcagacacct ggtatttttt atctcaaacc agcgtgactg atgtgtaagc gttgaagtaa
      421 ggaggcgatt atcgcgttat attccagccg cgtgccttcc agagtgcagg cagctgcgcc
      481 agctcggtaa atgtggtgac tttcgggtga acgatcggtt tattgtgcgg gtcagcgcag
      541 aagtaaaaca cttccattcc ggcatctatc cctgattgcg caccggcgct ggagtcatcg
      601 accagaatgc agttttcaac gtttacattc atcgcttttg ccgcatggaa cattaacgcc
      661 gggtcgggct tccaacgctg gatatcgtag ccgctgaaca gtttttccgg gaagtagtgc
      721 agcatcttga gcttacccag cgaatgctgc attttgttga tcggaccgtt agagacgacg
      781 cacatcggca cgttaatgct cgccagcaat tcgttcgctc ctgcgatgtc ctcaagttcg
      841 gtatcaaaca gacgcgccac ttctgcgcgg taaacgtgct cggcatcggc ctggatcatc
      901 gtcacgccct gttctttact gatgatgtcg atgatttcgt agagttttac gcctttaaaa
      961 cgggtaaaaa tctcctccag gtcaacgtga atgccaaatt ccctgaacat cgtgacatag
     1021 gcgcgagagc aaatgacctc gctatcgacc agcgtaccgt cgcagtcgaa aaataccgct
     1081 tctatctggg acatgtcttt cctttatcgt tagtttaacg ttttcgtcat gccaattcgc
     1141 atgacgcaat cgttgccgta taagcaaata caatgaaaaa aagttatctt cagccgtcca
     1201 tattgtctca ttttggtata cgatagcgac ggattttccc tccttgttcg gaaatagata
     1261 atgagtcaac aacacacaac ccaggcttct ggccagggga tgctggaacg cgtgtttaaa
     1321 ctgcgcgaac atggcacgac ggcacggacc gaagtgatcg ccggttttac caccttcctg
     1381 acgatggttt acatcgtttt tgttaacccg caaattcttg gcgttgctgg catggatacc
     1441 agcgccgtct tcgtcactac ctgtctgatt gctgcattcg gcagtattat gatgggactg
     1501 tttgctaacc tgccagttgc actggcaccc gctatgggcc tgaatgcgtt cttcgctttt
     1561 gtggttgtgc aggcgatggg cttgccgtgg caagtcggga tgggcgcaat cttctggggt
     1621 gcgattggtc tgctgttact gacgattttc cgcgttcgct actggatgat agccaacatt
     1681 ccggtaagtc tacgtgtggg catcaccagt ggtatcggtc tgtttattgg catgatgggg
     1741 ctgaaaaacg caggtgtgat tgtcgctaac ccggaaacgc tggtgagcat cggtaacctg
     1801 acttctcaca gcgtgctgct ggggatcctc ggcttcttca tcatcgccat tctggcctcg
     1861 cgcaatattc acgcggcggt gctggtttcc atcgtggtga caacgctgct gggctggatg
     1921 ctgggtgatg tgcactacaa cggcatcgtt tctgcgccgc cgagcgtaat gactgtcgtg
     1981 ggtcatgtag atttagccgg gtcgtttaac ctcgggctgg caggggtgat tttctctttc
     2041 atgctggtca acttgtttga ctcctccggt acgctgattg gcgtgaccga taaagcaggt
     2101 ctggctgatg ataaaggtaa attcccgcgc atgaagcagg cgctgtatgt cgacagcatc
     2161 tcttccgtga ccggttcgtt tatcgggact tcttctgtta cggcgtatat cgagtcttct
     2221 tccggcgttt ccgttggggg gcgtaccggc ctgacggcag tcgttgttgg tctgctgttc
     2281 ctgctggtta tcttcctgtc gccgctggcg gggatggtgc cgggatatgc cgcagctggc
     2341 gcgctgattt acgttggcgt gttgatgacc tcaagtcttg ctcgcgtgaa ctggcaggat
     2401 cttactgaat ctgttccggc gtttattacc gctgtgatga tgccgttcag cttctcgatt
     2461 accgaaggta ttgcgctggg ctttatctcc tactgcgtga tgaaaatcgg taccggacgt
     2521 ctgcgtgatc taagcccgtg cgtaatcatc gttgcgctgc tgtttatcct gaagattgtg
     2581 tttatcgacg ctcactaaaa tcgatagcgc gttaaaaacc cgccatgcat gattgctggc
     2641 gggtttttta tttagatctt aactcgctga ataaactcac caaatgcggt taattgcccg
     2701 gtcaggtggt ccagcgtacc ctgatcaatc acttctccgg tttgcggatc aactttgttc
     2761 tgaatcacgc cgcccataaa ttccggcttg ttcatcacca ttgcatcgag gaaaaccaga
     2821 atctggcgca ggtgatactg acagcgcgcg ccgccaatca cgcccattga gctggtctga
     2881 atcaacaccg gtttaccggc cagcggttga tccggcaggc gggaaagcca gtcgatggca
     2941 tttttcagcc cgcccggtac cgagtagtta tattccggcg tgacgatcac cacaccgtca
     3001 gcctgacgga tctgttccgc cagagcttca accgttgctg gaaaaccttc ttcctgctgt
     3061 acgtcagcgt catacaaggg aatgtcggca atggaaggta acgcattgac ttccatgctc
     3121 gccggagcaa ttttcggcag ggtacgtgca accatgccat taaatgagcc tttgcgcagg
     3181 ctccccagta acgtaaccac ctgcaatttt tcagacatga tgactcctgt ggttgtctat
     3241 caatttggcg aaaaagcctt cacggtagag agctgggcaa aacgcatcat ccggctggta
     3301 ggattgttgg cgcggctgtg aatatcgggc aggcttttcc agccgtgttt gccatctaac
     3361 tcccagacac tgagcttttc aatcgtgggc gtgaccgcca cggaccacac cagcacgtcc
     3421 tccgcgtcgc ataacgcttc tacatgattt acatgagcac atttcaggcg tccggcaatg
     3481 ggcagcagct gcagatcgcg cggatcgtca ttcaaaacat caccggttag ttttagcacg
     3541 cttcggcgca gcgtgatgag ctgcgcccgc gcttcgttag gatcgttttg tttactgatc
     3601 catagcgatt cattgctgga aaaggtgtgg ttatcgggcg cgtgtgggct atgaaacccg
     3661 cgcgtcgcac gctgcagttc catatcgagg ccacattcac cttcggttgt taacgccacg
     3721 ccaaccatat tcccggcata ggaaatagaa aacgaaggca aatttttatc gctgaaaacc
     3781 ggtttacctt tcggcagggt gacgatttcc ggcaattcgc caatgccata cagcatgaac
     3841 atcagttctg cgagtaaacc tctggacgcc agaaaacggc tttgacgatg agggggaatg
     3901 tttcgggctt cttgatgaca ctgggagggg agacgaacag aaatcagatg tccttccgtt
     3961 aaaatccctc gggcaaagtg agtcgccatt tttcgctcca tgcttaatgg tccattatga
     4021 atacaagagt aatcatttac tggaatgatg gacagactaa agcgactaaa agttcgattc
     4081 agataagttt attacaactt ttttacattt cattgtgaaa ttgggtcgcg tttcatacga
     4141 ttcggttatg ccatcgacgc gtaaagattt ttaatggttt cccgtaacca gacgatcttc
     4201 ggattacggc tgttccgttt atgccacaga agggtaaaag ggacttccag ctttttttgc
     4261 tggctttcat caaacgggag aggaagagca accaacggca gttggtggag ttgattgtag
     4321 tactggcagt agcgcggcgc ggtcgccagt aacagattgt cgggctgtgc tgccataaac
     4381 agtgactgct cgaattccgg catgctcata gcaatcgtgc gttcgcgccc cagctcctgt
     4441 aacacattgt ccagcgccca ggtatcgctc tgttcccagc aaatgctgat atgcggataa
     4501 cgtaaaaagg tgtccagatt ccatgcttca tgcagtgccg gatgatcttt gcgtaaccag
     4561 acgcagggca catcactaaa cagcacttca taatcaatgg ctaacggtag cgagcttaac
     4621 agctcccgcg aacggggatg actttcgcga ccggaaaaac caatatccac ttcaccacga
     4681 gtaatggcat ctaaggaatc gtaatcccag ttacgtaatt tgatggtcgc ctgcgggtaa
     4741 cgttggtaga tccgtttcga cagcgcatta agcatgatca tcattagcgg tgattctgct
     4801 gccagctcaa acttcaggcc gcgcggtgtc tggtggtgcg gtttatccag cagcaggttg
     4861 ctcatttgca tccactccgc cagattttgc tccatgctga ccattagcgg tgtgggcgac
     4921 agccccagcg gtgagttcac aaagagcgga tcgtcaaacc acgctcttaa ctttgccagc
     4981 gacttactca ccgccgaagg ggtcacgttc atccgcttcg ccgctttggt cacgctacgc
     5041 tcctgcatca gcagttgcag acagagcagc agattgagat caagcgtggt gatggatttc
     5101 ttcatgagcg gcaaccgggc gtccaggcgc gacgaacata atcagcaaca ggctcactat
     5161 gctacaggca atcagaatcc cgatcagcat attccatgcg ccgataccaa ccaccgccgc
     5221 cagccaaatc cacagtgacg aaccgcaaac ttgcgcaata cctaaggtcg agctggctac
     5281 gcccgcgcgt agtgaaaacg gccctaacgc ctgactcatc gctacgccaa aacctaccga
     5341 gaaaccggcg caaatcagcg tgataccaaa cagcgaaacc gcatgggaag gtgaaacggc
     5401 aagggtgatc cccgccgcca ggaataacac ctgtgaggtg atcatcaacg tacgtggctt
     5461 aaaaattccc agcgcaaacg gcgtggagaa tgaaacggtc atgctgacgc cagcggtcaa
     5521 cgccataatg gtggcgtatt ctccgcgctc aaaacccatg atttccatca gcaatactgg
     5581 cgacgtgttg acgaaggtga ggatcaccga aacgctgagg gtggtgataa ccacacggct
     5641 gaggaaaaac cggttaagca gtgactcgct attttctcgt ggtttgtccg aagctgcggg
     5701 ggccgcaggg cgcgtttctt ttaaaataaa caaagacaac atcagtaccg cgatgcccat
     5761 cgttgccatc gtccagaaca gactctgcca agggaattta agcataatca ggtgtccgag
     5821 caccggcgct aacaccggaa tgatgcaggt aatgccgttg agtaacgaca gcactttagc
     5881 ccgacgtcga tcatccagcg tgtcgcgtaa aatggcgaac gccaccacgt aacaacagcc
     5941 cgcgcccaac ccctgtagaa agcgccctgc aagaaataac gtgctggttt cagccagtga
     6001 acagaacacc gaggcgataa taaatagcgc cgcgccgggt atggtgacag gctttctccc
     6061 tgaacgatcg gccactttac cggcaaataa catcgcagct gccatgcccg ccagataaac
     6121 ggagaacgca atatgcaact gcgcttcgct ggcattgaga tcggcggcga tgcgcggtaa
     6181 accaacgagg tacatatcaa tcccggcggg ataaagtaaa accagggcaa aactacaaac
     6241 caaaaagcgg gacatgggct aaagcgtcct gatagtaagg tgacgcaaag catacgtggt
     6301 gaaggagaat caggcgagtt gccatttgga cataagtgat ttcctgtcag gcaagaagcc
     6361 agcgaatggc tggcttcttg aaggatttag ccaaatttag gtaacacgtt aaagacgtta
     6421 ccgaaccagc ataaaattac ggttatacca aagagaatga caatcgccgg aataagattg
     6481 ccgccccaga ccgtgaacat ctgattggga aacttcttgc gagctttgat tgccagcact
     6541 gcgggaataa tgaccgccca gatggtggcg cacagtccgg caccgccgat cccgtaaatg
     6601 aagccgttcg ggaagatcag atacaacaaa gcaggtggca ggaaggttaa cagcacggtt
     6661 ttgaaacgcc cgccgtggga gttatcaatc ttaaacagat ccgccagata atcgaacaat
     6721 cccagcgtga caccaaagaa cgaactggca acagctaagt tggagaacac cagcaggcaa
     6781 aactcgataa tcccatgctg tttggtgccg aggaacgatt tcaccagcga atcaacgttg
     6841 ccgcctgagg agattatcgc cttaaagctt tcgcgcggaa tattccccat cgtgcaatag
     6901 agccagaaga gataaatcac cagcgccagc agcgaaccaa agaccacgct tttgattaac
     6961 ttatctttgc gtttgccata gcaaataatc aggctgggaa tattgccgtg aaaaccaaat
     7021 gacgccagac acaccggcaa agccataaag atatacggga agtaagacgt tcccgcagtg
     7081 gtgctggtgg catcgcgcag aatggagtaa tcgacctgga agaagaaaga accaaacacg
     7141 atcacaaagg agataatctt cagcccgagg aacaatgagg taatacgact ggcggctaac
     7201 gagcttatcc acaatacgct ggcaacgaaa atggctgtgc agatcccgac aatacgcgga
     7261 ttagcgtgat agcccaaatt cattgatatt gtttcactaa tgatcgcacc attagcagag
     7321 atataggcat aagtgaggat atagagaacg aaggcaacgg taataccgct gataatgttc
     7381 caggtgttac cgattaaatc tttggtgatg gtgttaaaac tggagccgac aggataattt
     7441 aaatttgctt ctaataacaa taacccggaa tgaagcattg aaaaccaggc aatgataagg
     7501 ataaaggcac cccagaaaaa ccaggcaccg gcaagatcaa caggtaaagc aaacatacct
     7561 ccaccaatta ctgtacctgc tataaccata acaccccaaa atgcagagtg ctttttttca
     7621 gcttgatcag tcatgatgcc acctttagag gaaggctatt tttgttattg aggatgtagg
     7681 gtaagagagt ggctaacatc cttatagcca ctctgtagta ttaattaaac ttctttcagt
     7741 tttgcggtga agtgacgcaa tacttttggc tcataggtaa aggttaaccc tttaatattc
     7801 gccgcgttct ctttcacatg tttgaaggct tcaataatga agtccatatg tgtttgagta
     7861 tatgttgcgc gcggaatggt taaacgcagc agttcagccg ggcatggtag ttgtttaccg
     7921 gttttcgggt cgcggcctaa caggaaagag ccaatttcta ccgcacggat accggcgact
     7981 ttatacaact cgcaggccag cgcctgtgct gggaactgat ctgccgggat atgcggcagc
     8041 agtttaccgg catcaacgaa tgccgcgtga ccgcccgcct gctggcagac aacgccaatc
     8101 tcttccagac catcgaccag atactgcacc tgcgcgatac gataagccag ccagtccaga
     8161 ttcatgccgt catacagacc taccgccaga cgctccatcg cgccgccttc caggccgcca
     8221 tatgtcggga agccttcctg taccacgcaa agggttctgc attcggtgta cacatcaaag
     8281 aagctgtcgt ctttcatgca cagcaagccg cccatcggca ccatcgcatc tttcttggcg
     8341 gacatcgcca gcatatcggc atatttgtag gtttcgcggg tgatctgctc gatggtccag
     8401 tctttgtatt ctgcttcacg ctgcttgatg aaataggcgt tttcggcaaa gcgtgcggag
     8461 tccatgacca ccggaatatc gtatttcttc gcgatgctgt acatcgcttt taagtttgcc
     8521 agtgaaaccg gctgaccacc tgcggagtta ctggtgatgg ttgcaacgat atacggcacg
     8581 ttattcgggc caacttcttc aataccgcgt tctaatccct caaggtcaaa gttgccttta
     8641 aagtcgtaac gcacgccagt atcgaaggct tctttgatat agacgttacg cacggtacag
     8701 ccgttaatct ggctatggcc ctgcgtggta tcaaagaaat agttagagaa cgccaccatt
     8761 ttgctgcgat ccaggccttt ttcctgctcg cgttttttaa tcagtaccgg aatatagatt
     8821 tgttctgcgc cacggccctg gtgagtcgga atggtgtatt gataaccaaa gatatttttc
     8881 actgactcgg ctaacgcata gtagctgcga ctgccgctgt aggcttcgtc gccgcgcatc
     8941 atcgcggcct gcatgctctg cgtcaccgcc ccggtgccgc tgtcggtcag taaatcgata
     9001 aacacatctt cgctatccag caggaacggg ttcataccgg atttaataat tgcctcttca
     9061 cgataagcgc gagtggtacg ttttactggc tcaataacac gaatgcggaa cggttcaggg
     9121 agatgtttaa agttttccat tacataatcc ttcatttatt ttaattacag tgatccctgt
     9181 gaatattaca tttgcaatat ccattaattc gtcagatata tatacaaagg ccaacattta
     9241 ctaaaacaag taaataaatg agagatagcc tttgcaaaag acaaaattaa gatatagcaa
     9301 actaatcgat cacattgaat ctaatcggtt tggctctggt gatggctaca gaagggtaaa
     9361 ttaagggcgg tgatcgacaa tcttattgtc gatattgaac cattttgagg tcacacatat
     9421 atgtaagata ttcataatgc acttatcctc gaaagacacg aggctacagt ataatactca
     9481 agaaatttgt ctattctgaa attgtttaaa tgtgaatcga atcacaatcg ttcgggaagc
     9541 aatattaaat gcttttttta aagattataa attacgtaag aattttaatg tttaaaaaaa
     9601 gggttgagga gtaacaggag tactaacaat gaagcgaagc cgcatctgac agtcagaatg
     9661 cggcttcgca agcgcggtta cttaccaata cagaagctgg agaaaatccg ccccaacagg
     9721 tcgtctgaag taaattcccc ggtgatttcg cttaagttct gctgcgccag gcgcaactct
     9781 tccgccagca gttcacccgc ccaggcacct aacagttgcg ctttaccttg ctgcaaatgc
     9841 tctgccgcct gttccagcgc ctgtaggtga cgacgacgcg ccaggaagcc gccttccata
     9901 ttggtgtcaa agcccatgct ctgtttgaga tggttacgca gcacgtccac gccttcgcca
     9961 gtccttgccg agagacgaat caacgcatga ccgttcactt cactcattcc cagcgtttcg
    10021 ccggtgatat cggctttatt gcgcaccacg gtgatcggca gtttcgcggg cagacgggcg
    10081 ataaattccg gccagatctc tgccggatca acggcgtctg tcgtggtgcc atcgaccata
    10141 aacagcacgc ggtcggcctg ttcaatttcc tgccacgcgc gctcgatacc aatacgttct
    10201 acttcgtcac tggcttcacg tagcccggcg gtatcgatga tatgcagcgg cattccgtca
    10261 atgtggatat gctcacgcag cacgtcacgc gtggttccgg cgatatcggt tacgattgcc
    10321 gcttcacggc ccgccagcgc gtttaacagg ctcgatttac cggcgttagg acgtccggca
    10381 atcaccactt tcatcccttc gcgcaacaaa ctaccctgac gtgcttcagc acgcactgca
    10441 tcaagatcgg caataacgtc attgagctgg gcttcaattt tgccgtcgga gaggaaatcg
    10501 atctcttcat ccgggaaatc aattgccgct tcgacgtaaa tgcgcaagtg ggtgagggct
    10561 tccaccagat ggttgacccg tgcggagaat gcgccttgca gcgagtttag cgccgaacgg
    10621 gccgcctgtt ccgagctggc gtcgataaga tccgcaatcg cctcggcctg ggctaagtcg
    10681 agtttatcgt tcagaaatgc gcgttcggaa aactcaccag ggcgggcaat ccgcaggccg
    10741 ggaatggtca gaatgcgttt taacagcagg tcgaggatca ccggaccgcc atgaccttgc
    10801 agttccagca catcttcgcc ggtgaacgag ttcgggccag ggaaccatag cgcaatcccc
    10861 tgatcgagca cgctgccgtc ggcgtcttta aacggaagat aatcggcgta gcgcggcttt
    10921 ggcagtttac ccagcacggt ttcggcaacc tcacgggctt tgaggccgga gatgcgcagg
    10981 atgccaacgc cgccacgtcc cggaggcgtg gcctgggcta cgatagtgtc attatcgctc
    11041 atgatgttcc tgttgctttg tgtggcggat acgcggtgct tatccgccct acgaaaagaa
    11101 aaaaaaaggc ggtcaactga ccgcccttat tttagcgaaa actcaccgaa tcaggatttt
    11161 ttcttctcgc ggctatgcag gccacgtttt tccagaccac ggtaaatcag ctgctgctga
    11221 ataatggtta ccaggttgct gacgatatag tacagcacca gacctgacgg gaaccacagg
    11281 aagaacacgg tgaagatgac cggcataaag gtcatgatct tctgctgcat cgggtcggtc
    11341 acggtggtcg gcgacatctt ctgaatgaag aacatcgtta cgcccatcag gatcggcagg
    11401 atgtagtacg ggtcctgtgc agacaggtcg tggatccaca gtgcaaacgg tgcctgacgc
    11461 agttcaacgg aacccatcag catgtagtac aacgccagga agattggcat ctggatcagc
    11521 agcgggaagc agccgcccag cgggttaacc ttctcagctt tgtacagcgc catcatttcc
    11581 tggctgatac gctgtttgtc atcgcccaga cgctcacgca tcgcctgaat cttcggctgc
    11641 agcatacgca tcttcgccat ggaggtgtac tgcgctttgg tcagcgggta catgatgcca
    11701 cgaacgataa aggtgatgat gataatggag aagccccagt tacccacaaa gctatggatc
    11761 catttcagca gtttgaacag cggctgagag atgaaccaca accaaccgta atcaacggtc
    11821 agatccaggt gcggagcaac agctgccatt ttgtcctgaa tttccgggcc aacccacagg
    11881 gtgctgttca tcgcgccagt ctgaccaggc tgaaccagta ccggctgaga tttatagccg
    11941 atagcggcga tgccgttacc cagattagca gtatagaagt tattggtacc gtcgttatgc
    12001 gggatccacg ccgtcgcgaa atactgttgc agcatcgcca cccaaccacc tttcgaagag
    12061 atgttcaggt tttcgttatc ggcaatggta tcgaacttgt atttctcgta cttctcgtca
    12121 ggcgtggagt acgccgcgcc acggaaggtg tgcagtgcga aattgctgct tccggtatcg
    12181 agatgcggtg gcagagtgat ggattgcttc aactgaccaa aggtggagat ttccagcggt
    12241 ttctcgccag cgttctgcac gttgtagttg acgttgacag cgtaatcacc acgtttcagg
    12301 acaaacgttt tggtaaacgt gttacctgcc gcgtcggtat acgtcatcgg cacctgcagt
    12361 tcgttttgac cttcagccag cacataagcg tccttttcaa cgttatacag cggacgcggg
    12421 ccgttagccg ggttatccgg gccatcacga ccggtcagac cgctctgtgc ctgataaata
    12481 aactgcggtg aagtttccag cagctggaac ggctgggtag agtttagctc tttcgggtaa
    12541 gcaggcagca gagcttgctc aacatcacca ccacgggtgt tgatggtcag atcaagcacg
    12601 tcggtcttaa ccgagatcag tttcccctgg ccactggccg gtacgccctg gtcggcggcg
    12661 ctacccgctg cggtggtcgt tgtctgcgtg gtctgttggg cctgaggttg cgggttttta
    12721 tcctgctccc aggcttgcca gatcatgaaa gacacgaaca gcaaagcgat gactaaaaga
    12781 ttgcgttgcg aatccatcgt tagtgttctc tggtatcaaa tggtccgggc gggacgggat
    12841 cgtcaccacc agggtgtaaa gggtggcatt ttaatacgcg tttcaccgtc aaccaactgc
    12901 cttttatcac tccaaacctg cgcaatgcct caattccgta gcttgaacag gttggagtga
    12961 aacgacaatg cggcccgagt agcggactaa tcaggcgttg atagacccga atgagggcta
    13021 tcaggacccg cgagccaggc gacagtggcg gcgccataat ttttccaacg cttccgagag
    13081 agcacggtta tcgaggtcgg caaccccttt tttcgccacc accacgaaat ccatagccgg
    13141 gagttcatgt tggcgcagac ggaagctttc acgcgtcaga cgtttaatcc gattgcgttc
    13201 atgggcgcgt cgaacgtttt tcttggcgac tgtaagaccg atacggggat gccccagcga
    13261 attcaggcgg ccgagaatgg taatttgcgg cgtgccagcc cgttgtggct gctggaagac
    13321 gaatgtgaat tgactgggag ttaacaagcg taactccctg ggaaatgcga gcttaaccac
    13381 tcaggggtta gctttattac ttagaaacgg tcagacgagc gcggccttta gcacgacgac
    13441 gtgccagaac ctgacgacca tttttagtag ccatacgagc acggaagccg tgagaacggt
    13501 tgcgcttcag tacagacggt tgaaaagtgc gtttcatggc gatttctacc taaacttgaa
    13561 taaattcaat ggctttattg gatatccgcc gaaaaatgaa acgatggaca ccgaagccat
    13621 gggtgattaa agaggccgga ttgtaataat tgtacactcc ggagtcaatt ctctttcctt
    13681 atttaccgcg cttttccgca ccttttcgca gggaaaacgt acggcctcac accagtgaaa
    13741 accagcatgg cgcgccgggt ggaggattat acgggctgac gggtaaagcg caaggatcgt
    13801 cctggatctt tattagatcg attaagtcaa tttttgtcta tggtcattaa attttccaat
    13861 atgcggcgta aatcgtgtcc ggcccgcggc aggatcgttt acacttagcg agttctggaa
    13921 agtcctgtgg ataaatcggg aaaatctgtg agaaacagaa gatctcttgc gcagtttagg
    13981 ctatgatccg cggtcccgat cgttttgcag gatcttgatc gggcatataa ccgcagacag
    14041 cggttcgtgc gtcaccctca tgcagggtct tttcgacgta cgtcaacaat catgaatgtt
    14101 tcagccttag tcattatcga cttttgttcg agtggagtcc gccgtgtcac tttcgctttg
    14161 gcagcagtgt cttgcccgat tgcaggatga gttaccagcc acagaattca gtatgtggat
    14221 acgcccattg caggcggaac tgagcgataa cacgctggcc ctgtacgcgc caaaccgttt
    14281 tgtcctcgat tgggtacggg acaagtacct taataatatc aatggactgc taaccagttt
    14341 ctgcggagcg gatgccccac agctgcgttt tgaagtcggc accaaaccgg tgacgcaaac
    14401 gccacaagcg gcagtgacga gcaacgtcgc ggcccctgca caggtggcgc aaacgcagcc
    14461 gcaacgtgct gcgccttcta cgcgctcggg ttgggataac gtcccggctc cggcagaacc
    14521 gacctatcgt tctaacgtaa acgtcaaaca cacgtttgat aacttcgttg aaggtaaatc
    14581 taaccaactg gcgcgcgcgg cggctcgcca ggtggcagat aaccctggcg gtgcttataa
    14641 cccgttgttc ctttatggcg gcacgggttt gggtaaaact cacctgctgc atgcggtggg
    14701 taacggcatt atggcgcgca agccgaatgc caaagtggtt tatatgcact ccgagcgctt
    14761 tgttcaggac atggttaaag ccctgcaaaa caacgcgatc gaagagttta aacgctacta
    14821 ccgttccgta gatgcactgc tgatcgacga tattcagttt tttgctaata aagaacgatc
    14881 tcaggaagag tttttccaca ccttcaacgc cctgctggaa ggtaatcaac agatcattct
    14941 cacctccgat cgctatccga aagagatcaa cggcgttgag gatcgtttga aatcccgctt
    15001 cggctgggga ctgactgtgg cgatcgaacc gccagagctg gaaacccgcg tggcgatcct
    15061 gatgaaaaag gccgacgaaa acgacattcg tttgccgggc gaagtggcgt tctttatcgc
    15121 caagcgtcta cgatctaacg tacgtgagct ggaaggcgcg ctgaaccgcg ttattgctaa
    15181 cgccaacttt accggacgtg cgatcaccat cgacttcgtg cgtgaggcgc tgcgcgactt
    15241 gctggcattg caggaaaaac tggtcaccat cgacaatatt cagaagacgg tggcggagta
    15301 ctacaagatc aaagtcgcgg atctcctttc caagcgtcga tcccgctcgg tggcgcgtcc
    15361 gcgccagatg gcgatggcgc tggcgaaaga actgactaac cacagtctgc cggagattgg
    15421 cgatgcgttt ggtggccgtg accacacgac ggtgcttcat gcctgccgta agatcgagca
    15481 gctgcgtgaa gagagccacg atatcaaaga agatttttcc aatttaatca gaacattgtc
    15541 atcgtaaacc tatgaaattt accgtagaac gtgagcattt attaaaaccg ctacaacagg
    15601 tgagcgggcc gttaggtggt cgtcctacgc taccgattct cggtaatctg ctgttacagg
    15661 ttgctgacgg tacgttgtcg ctgaccggta ctgatctcga gatggaaatg gtggcacgcg
    15721 ttgcgctggt tcagccacac gaaccagggg cgacgaccgt tccagcgcgc aaattctttg
    15781 atatctgccg tggtctgcct gaaggcgcgg aaattgccgt gcagctggaa ggtgagcgga
    15841 tgctggtgcg ctccgggcgt agccgttttt cgctgtctac cctgccagcg gcggatttcc
    15901 cgaatcttga tgactggcag agcgaagtcg aatttaccct gccgcaggcg acgatgaagc
    15961 gtctgattga agcgacccag ttttctatgg cgcatcagga cgttcgctat tacttaaacg
    16021 gtatgctgtt cgaaactgaa ggtgaagaac tgcgcaccgt ggcgaccgat ggtcaccgtc
    16081 tggcggtctg ttcaatgcca attggtcaat ctttgccaag ccattcggtg atcgtgccgc
    16141 gtaaaggcgt gattgaactg atgcgtatgc tcgacggtgg cgacaatccg ctgcgcgtgc
    16201 agattggcag caacaacatt cgcgcccacg ttggcgactt tatcttcacc tcgaaactgg
    16261 tggatggtcg cttcccggat taccgccgcg ttctgccgaa gaacccggac aagcatctgg
    16321 aagctggctg tgatctgctc aagcaggcgt ttgcccgtgc ggcaattctc tctaacgaga
    16381 aattccgcgg cgtgcgtctg tatgtcagcg aaaaccagct gaaaatcacc gccaacaacc
    16441 cagaacagga agaagcggaa gagatcctcg acgttaccta tagcggtgcg gagatggaaa
    16501 tcggcttcaa cgtcagctat gtgctggatg ttctcaacgc gctgaaatgc gaaaacgtcc
    16561 gcatgatgct gaccgattcg gtttccagcg tgcagattga agatgccgca tcacagtcgg
    16621 ctgcctatgt tgtcatgcca atgagactgt aatgtccctc acccgcttgt tgatccgcga
    16681 tttccgcaat atcgaaaccg cggatctcgc tttatctccc ggctttaact ttctggtagg
    16741 tgccaacggt agtggcaaaa ccagcgtgct ggaagccatc tatacgctcg gccacggtcg
    16801 ggcgtttcgc agtttgcaga ttggtcgcgt cattcgccat gagcaggagg cgtttgttct
    16861 ccacgggcgt ttgcagggcg aagagcgcga gacggcgatt ggcttaacca aagacaaaca
    16921 gggcgacagc aaagtccgca tcgacggtac tgacgggcat aaagtcgcgg agctggcgca
    16981 cctgatgcca atgcagctga taacgccaga agggtttact ttactcaacg gcggccccaa
    17041 atacagaaga gcattcctcg actggggatg ctttcacaac gaacccggat ttttcaccgc
    17101 ctggagcaat ctcaagcgat tgctcaagca gcgcaatgcg gcgctgcgcc aggtgactcg
    17161 ttacgaacag ctacgtccgt gggataaaga actgatcccg ctggcggagc aaatcagcac
    17221 ctggcgcgcg gagtatagcg ccggtatcgc ggctgatatg gccgatacct gcaagcaatt
    17281 tctccctgag ttttctctga ctttctcttt ccagcgcggc tgggagaaag agacagaata
    17341 tgctgaggtg ctggaacgta attttgaacg cgatcgccag ctaacctaca ccgcgcatgg
    17401 cccgcataaa gcggacttac gcattcgcgc cgacggtgcg ccggtggaag ataccttatc
    17461 gcgtgggcag cttaagctgc tgatgtgcgc cttacgtctg gcgcaaggag agttcctcac
    17521 ccgtgaaagc gggcggcggt gtctctacct gatagatgat tttgcctctg agcttgatga
    17581 tgagcgtcgc gggctgcttg ccagccgctt aaaagcgacg caatcacagg tctttgtcag
    17641 cgcgatcagt gctgaacacg ttatagacat gtcggacgaa aattcgaaga tgtttaccgt
    17701 ggaaaagggt aaaataacgg attaacccaa gtataaatga gcgagaaacg ttgatgtcga
    17761 attcttatga ctcctccagt atcaaagtcc tgaaagggct ggatgcggtg cgtaagcgcc
    17821 cgggtatgta tatcggcgac acggatgacg gcaccggtct gcaccacatg gtattcgagg
    17881 tggtagataa cgctatcgac gaagcgctcg cgggtcactg taaagaaatt atcgtcacca
    17941 ttcacgccga taactctgtc tctgtacagg atgacgggcg cggtattccg accggtattc
    18001 acccggaaga gggcgtatcg gcggcggaag tgatcatgac cgttctgcac gcaggcggta
    18061 aatttgacga taactcctat aaagtgtccg gcggtctgca cggcgttggt gtttcggtag
    18121 taaacgccct gtcgcaaaaa ctggagctgg ttatccagcg cgagggtaaa attcaccgtc
    18181 agatctacga acacggtgta ccgcaggctc cgctggcggt taccggcgag actgaaaaaa
    18241 ccggcaccat ggtgcgtttc tggcccagcc tcgaaacctt caccaatgtg accgagttcg
    18301 aatatgaaat tctggcgaaa cgtctgcgtg agttgtcgtt cctcaactcc ggcgtttcca
    18361 ttcgtctgcg cgataagcgc gacggcaaag aagaccactt ccactatgaa ggcggcatca
    18421 aggcgttcgt tgaatatctg aacaagaaca aaacgccgat ccacccgaat atcttctact
    18481 tctccactga aaaagacggt attggcgtcg aagtggcgtt gcagtggaac gatggcttcc
    18541 aggaaaacat ctactgcttt accaacaaca ttccgcagcg tgacggcggt actcacctgg
    18601 caggcttccg tgcggcgatg acccgtaccc tgaacgccta catggacaaa gaaggctaca
    18661 gcaaaaaagc caaagtcagc gccaccggtg acgatgcgcg tgaaggcctg attgcggtcg
    18721 tttccgtgaa agtgccggac ccgaaattct cctcccagac caaagacaaa ctggtttctt
    18781 ctgaggtgaa atcggcggtt gaacagcaga tgaacgaact gttggcggaa tacctgctgg
    18841 aaaacccaac cgacgcgaaa atcgtggttg gcaaaattat cgatgctgcc cgtgcccgtg
    18901 aagcggcgcg tcgcgcgcgt gaaatgaccc gccgtaaagg tgcgctcgac ttagcgggcc
    18961 tgccgggcaa actggcagac tgccaggaac gcgatccggc gctctctgaa ctgtacctgg
    19021 tggaagggga ctccgcgggc ggctctgcga agcaggggcg taaccgcaag aaccaggcga
    19081 ttctgccgct gaagggtaaa atcctcaacg ttgagaaagc gcgcttcgat aagatgctct
    19141 cttctcagga agtggcgacg ctgatcaccg cgcttggttg tggtatcggt cgtgacgagt
    19201 acaacccgga caaactgcgt tatcacaaca tcatcatcat gaccgatgcg gacgtcgacg
    19261 gctcgcacat tcgtacgctg ctgttgacct tcttctatcg tcagatgccg gaaatcgttg
    19321 aacgcggtca cgtctacatc gctcagccgc cgctgtacaa agtgaagaaa ggcaagcagg
    19381 aacagtacat taaagacgac gaagcgatgg atcagtacca gatctctatc gcgctggatg
    19441 gcgcaacgct gcacaccaac gccagtgcac cggcgctggc tggcgaagcg ttagagaaac
    19501 tggtgtctga gtacaacgcg acgcagaaaa tgatcaaccg catggagcgt cgttatccga
    19561 aagcaatgct gaaagagctt atctatcagc cgacgctgac ggaaaccgac ctttctgacg
    19621 agcaaaccgt tacccgctgg gtgaacgcgc tggtcagcga actgaacgat aaagaacagc
    19681 acggcagcca gtggaagttt gatgtccaca ccaatgctga tcaaaacctg tttgaaccga
    19741 ttgttcgcgt gcgtacccac ggtgtggata ctgactatcc gctggatcac gaatttatca
    19801 ctggcggcga atatcgtcgt atctgcacgc tgggtgagaa actgcgtggc ttgctggaag
    19861 aagatgcatt tatcgaacgt ggcgaacgtc gtcagccggt agccagcttc gagcaggcgc
    19921 tggactggct ggtgaaagag tcccgtcgcg gcctctccat ccagcgttat aaaggtctgg
    19981 gcgagatgaa cccggaacag ctgtgggaaa ccaccatgga tccggaaagc cgtcgtatgc
    20041 tgcgcgttac cgttaaagat gcgattgctg ccgaccagtt gttcactacg cttatgggcg
    20101 acgccgttga accgcgccgt gcgtttatcg aagagaacgc cctgaaagcg gcaaatatcg
    20161 atatttaatg gctttttgtt gctgataaaa tgacttagtc gtcagtccgg gcggagatca
    20221 tctccgccct ttttatttct gcaatccgca attatcatcc cgcagatcta tactttttgg
    20281 gtcaacacgt aacgctttac aggtgattat catggggctt tttgatgacg ttgtcggtgc
    20341 ctttctgaaa ggcgatgcgg ggaaatatca ggcgattttg agctgggttg aggagcaggg
    20401 cggcattcag gtgctgctgg aaaaactgca aagtggcggt ttaggtgcca ttctctcaac
    20461 ctggctgagt aatcaacagg gcaaccaacc agttagcggc gagcaactgg aatcagcgct
    20521 cggcacaaat gcggtgtccg atctcgggca aaaactgggc gtggatacca gtacagcttc
    20581 cagtttactg gcagaacaat tgccgaagat tattgatgca ctctcaccgc aaggtgaagt
    20641 gtcagcacaa gccaataacg atctgctttc cgcaggcatg gaactgctga aagggaaact
    20701 cttccgctaa gcaaatgggg agcatgcaac ccgcattgca tccccctttt ccctcgggtg
    20761 ttgtactgat ttttgagcgg aatcgcgtta gcatgggtca ggaaccaatc tacctgggga
    20821 actcatggct atcaaactca ttgctatcga tatggatggc acccttctgc tgcccgatca
    20881 caccatttca cccgccgtta aaaatgcgat tgccgcagct cgcgcccgtg gcgtgaatgt
    20941 cgtgctgacg acgggtcgcc cttatgcagg tgttcacaat tacctgaaag agctgcatat
    21001 ggaacagccg ggcgactact gcattactta taacggcgcg ctggtacaga aggccgctga
    21061 tggtagcacc gtggcgcaaa ccgctctcag ctatgacgac taccgtttcc tggaaaaact
    21121 ctctcgcgaa gtcggttctc atttccacgc cctggaccgc accacgctgt acaccgccaa
    21181 ccgagatatc agctactaca cggtgcatga atctttcgtt gccaccattc cactggtgtt
    21241 ctgcgaagcg gagaaaatgg accccaatac ccagttcctg aaagtgatga tgattgatga
    21301 acccgccatc ctcgaccagg ccattgcgcg tattccgcag gaagtgaaag aaaaatacac
    21361 cgtgctgaaa agtgcgccgt acttcctcga aatcctcgat aaacgcgtta acaaaggtac
    21421 gggtgtgaaa tcactggccg acgtgttagg tattaaaccg gaagaaatca tggcgattgg
    21481 cgatcaggaa aacgacatcg caatgattga atacgcaggt gttggtgtgg caatggataa
    21541 cgctattcct tcggtgaaag aagtggcgaa ctttgtcacc aaatccaacc tggaagatgg
    21601 cgtggcgttt gctattgaga agtatgtgct gaattaatca gtgggcgggc aaactgcata
    21661 aatgcgtttg cccgcagcga ttaacaattt ctggtcgtgc ataaaatcag gaactggagt
    21721 ggtgacgtta ctatatccag cgtaagagtg actggtagca gcgcattagc gaggccgcgc
    21781 ggaacgccat cagttgcttt gtacttataa aatcccaccg taaagggttg atggaaaacc
    21841 atcacgtttg agtaatccgc ttttttattt ttctggtgga tagagccttt caggccgtca
    21901 agtgcccagg tacaacgctg ggtattacaa ataaaaccat attgtgtcgc cagtgcttta
    21961 tcttcctcat tatcccagtc gtaatagagc gttattgaac cagaaaaatt agtatcactg
    22021 ctgcttaaaa taaatttcgc gttatcagaa acggtgattc tttcaccatg gattgccgga
    22081 tcgttcagca ttttaactac ctcatcgccg ccggtggtca acagatagtc caatgattca
    22141 ccaacaaaaa catagccttt cgtaccgtta ctatcttctg ccagcgataa acccttaatc
    22201 gtgtctgacc gccattgctc ggcatgtgga cggcttgcag tattggaaac caatccccag
    22261 gtgatacatc cggtcaacgc aaatgccaaa gaacacaaac cggcagcctt aaaaaatccc
    22321 ttaaaattca acttcatgat taatccttta aacgagtagc taagccgttg aaagcatact
    22381 cttctttccc tcctgtttag cgcctgttct cccttttcag atttctgccc gacgcatgtc
    22441 atttttttat gcattgttct ttttgtgatc taaattgtag tacaacaata taattttgta
    22501 ctacattacg catacggaaa acgcgaacgt catcacgctg gtactacaaa gttgccgcgt
    22561 tatgcatcga tcggggtaaa gtagagaaga acatacagag cacaaggact ctccatgact
    22621 ctcaataaaa ccgatcgcat cgtcattacg ctgggtaaac agatcgttca cggcaaatac
    22681 gtaccaggct cgccgcttcc ggctgaggcg gaactctgtg aagagtttgc aacctcgcgc
    22741 aacatcatcc gtgaggtgtt ccgttcgctg atggcgaagc ggctgattga aatgaaacgt
    22801 tatcgcgggg cgtttgtggc accgcgtaat cagtggaatt acctcgatac tgacgtgctg
    22861 caatgggtgc tggaaaacga ctacgaccca cggcttatca gtgcaatgag cgaagtgcga
    22921 aatctggtgg aaccggcgat tgcccgttgg gcggcagagc gcgcgacttc cagcgatctg
    22981 gcgcagattg aatcagcgct gaacgagatg attgccaaca atcaggaccg cgaagcgttt
    23041 aacgaagcgg atattcgcta ccacgaggcg gtgctgcagt cggtgcataa cccggtgtta
    23101 cagcaactta gcattgcgat cagttcgctg cagcgggcgg tttttgaacg aacctggatg
    23161 ggcgatgagg ccaacatgcc gcaaacgctc caggaacata aggcgctgtt tgatgcgata
    23221 cggcatcagg acggcgatgc ggcagagcag gcggcgctta ccatgatcgc cagctcgaca
    23281 cgaaggttaa aggaaatcac atgacagctc gctacatcgc aattgactgg ggatcgacca
    23341 atctgcgcgc ctggctttat cagggcgacc actgcctgga gagcaggcaa tcagaagcag
    23401 gcgtcacgcg cctgaacgga aaatctccgg ctgcggtgtt agcagaagtc acgaccgact
    23461 ggcgtgaaga gaatacgcca gtggtgatgg caggaatggt cggcagcaat gtcggctgga
    23521 aagttgcacc gtatttatct gttcctgccc gtttttcatc tattggcgaa caattaacgt
    23581 ctgttggcga caatatctgg attattcccg gattatgcgt ttctcatgat gataaccaca
    23641 atgtgatgcg cggcgaagaa acacaattga tcggcgcgcg tgctttggct ccttcctctc
    23701 tttatgtcat gcccggtacg cattgcaaat gggtgcaggc cgatagccag caaatcaacg
    23761 attttcgcac cgtaatgacc ggtgaattac atcatttact gttaaatcac tcattgattg
    23821 gcgcaggttt accgccgcag gaaaactctg ccgatgcctt cgcggctggt cttgagcgtg
    23881 gccttaatgc gcccgccata ttgccgcagc tttttgaagt tcgcgcatcg catgtgctgg
    23941 gaacacttcc ccgtgaacag gtcagcgaat ttctctctgg attgttgatt ggcgcagagg
    24001 ttgccagtat gcgcgactat gtgacccatc aacacgccat cacccttgtc gccggaacat
    24061 cgctgaccgc gcgctaccag caagcctttc aggcgatggg ttgcgacgtg gcggcggtag
    24121 cgggcgacac ggcatttcag gctggtataa ggagcatcgc tcatgcagtg gcaaactaaa
    24181 ctcccgctga tcgccatttt gcgcggtatt acgcccgacg aggcgctggc gcatgttggc
    24241 gcggtgattg acgccgggtt cgacgcggtt gaaatcccgc tgaattcccc tcaatgggag
    24301 aaaagcattc ccgccatcgt tgatgcatac ggcgataagg cgttgattgg cgcaggtacg
    24361 gtactgaaac ctgaacaggt cgatacgctc gccaggatgg gctgtcagct catcgttacg
    24421 cccaatatcc atagtgaagt gatccgccgc gcggtgggct atggcatgac cgtttgcccc
    24481 ggctgcgcga cggcgactga agcctttacc gcgatcgacg cgggcgcgca ggcgctgaaa
    24541 atattcccgt catcggcttt tgggccgcaa tacatcaaag cgttaaaagc ggtattaccg
    24601 caggacatcc cggtctttgc cgtaggcggt gtgacgccag aaaacctggc gcagtggata
    24661 gacgcaggtt gtgcaggggc gggcttaggc agcgatctct atcgcgccgg gcaatccgta
    24721 gaacgcaccg cgcagcaggc agcagcattt gttaaggcgt atcgagaggc agtgcaatga
    24781 aaatcaccaa cattactacg tatcgtttac ctccccgctg gatgttcctg aaaattgaaa
    24841 ctgatgaagg cgtggtcggt tggggcgagc ccgtgatcga aggccgcgct cgtacggtgg
    24901 aagcggcagt tcacgagctg agtgactatt tgattggtca ggatccatcg cgcatcaatg
    24961 acttatggca agtgatgtat cgcgccggat tttatcgtgg cggtccgatt ctgatgagcg
    25021 ccatcgccgg gatcgaccag gcgttatggg atatcaaagg taaagtgctg aatgcgccgg
    25081 tctggcaatt gatgggtggc ctggttcgcg acaaaattaa agcctacagt tgggtcggcg
    25141 gcgatcgtcc ggcggatgtt atcgacggca ttaaaaccct gcgcgaaatc ggcttcgata
    25201 ccttcaaact gaacggttgt gaagaactgg ggctaattga taactcccgc gcggtagatg
    25261 cggcagtcaa caccgtggca caaattcgtg aagcctttgg caatcagatt gagtttggtc
    25321 ttgatttcca cggtcgcgtc agcgcgccga tggcgaaagt gctgattaaa gaactggagc
    25381 cgtatcgccc gctgtttatt gaagagccgg tgctggcgga acaggccgaa tactacccga
    25441 aactggcggc acaaacacat attcctctgg cggcgggtga acgcatgttc tcacgcttcg
    25501 attttaaacg cgtgctggag gcgggcggta tttcgattct gcaaccagat ctctctcatg
    25561 caggcggtat taccgaatgc tacaaaattg ccggaatggc agaagcctat gacgtgaccc
    25621 ttgcgccgca ctgtccgctc ggaccgattg cactggcggc ttgtctgcat atcgactttg
    25681 tttcctataa cgccgtactt caggaacaaa gtatgggaat tcattacaac aaaggcgcgg
    25741 agttactcga ctttgtgaaa aacaaagaag acttcagcat ggttggcggc ttctttaaac
    25801 cgctaacgaa accgggctta ggcgtagaaa tcgacgaagc taaagttatt gagttcagta
    25861 aaaatgcccc ggactggcgt aatccgctct ggcgtcatga agataacagc gtagcagagt
    25921 ggtaattcct gccacgtaag cccctcatcg ggcactaaaa cagcaataca aaaatataac
    25981 cctctgtaaa ttacagggca tggtgagcgg cttcgctatg cccaaaatct ggagaaagct
    26041 cgctatggat attcccgtta atgcagcaaa gccggggcgt cggcgttatc tgacgctggt
    26101 gatgatcttt attacggtgg tcatttgtta tgttgaccgc gctaacctgg ccgtggcttc
    26161 cgcccatatt caggaagagt tcggtattac gaaagcggaa atgggctatg tattttcggc
    26221 cttcgcctgg ctttatacgc tatgtcagat ccccggcggt tggtttttag atcgcgtagg
    26281 ttcacgcgtg acttatttta ttgcgatatt tggctggtca gtggcgacgt tattccaggg
    26341 ctttgccacg ggattaatgt cattaattgg tctgcgcgcg ataaccggta ttttcgaagc
    26401 gcccgctttc ccgaccaata accggatggt gaccagctgg ttcccggaac atgaacgcgc
    26461 ttccgccgtt ggtttttata cgtctggtca gtttgtcggt ctggcgtttc tgactccgct
    26521 gctgatctgg attcaggaaa tgttgagctg gcactgggtg ttcattgtca ccggtggtat
    26581 cggcattatc tggtcgctga tttggtttaa ggtttatcag ccgccgcgcc tgactaaagg
    26641 catcagcaaa gctgaactgg attacattcg tgatggcggc ggtctggtgg atggcgatgc
    26701 gccggtgaaa aaagaggcgc gtcagccgtt aacagccaaa gactggaaac tggtgttcca
    26761 tcgtaaactg atcggtgtct atcttgggca atttgcggtg gcttctacac tgtggttttt
    26821 cttaacctgg ttcccgaact atttaaccca ggaaaaagga atcacggcgc tgaaagcagg
    26881 ctttatgacc acggtgccgt tcctcgcggc gtttgtcggc gtcctgctct ctggctgggt
    26941 cgcggatctg ctggtacgta agggcttttc actgggcttt gcgcgtaaaa cgccgattat
    27001 ctgcggcttg ctgatctcca cctgcattat gggcgctaac tacactaacg atccgatgat
    27061 gattatgtgc ctgatggcgc tggcattctt cggcaacggt tttgcttcga ttacttggtc
    27121 gctggtctct tctctggcac cgatgcgcct gattggttta accggcggcg tgtttaactt
    27181 tgccggtggt ctgggcggca tcaccgttcc tctggtggtg gggtacctgg cgcagggtta
    27241 cggtttcgcg cctgcactgg tttatatctc cgccgttgcg ttgattggcg cgctctctta
    27301 catcctgctg gtgggcgatg tgaagcgcgt tggctaatct ttcaactgtg gaatatgcgc
    27361 cacaccactg cgcataatcc actttcttaa agccggtgcg gtcaggcatc ggcttttgac
    27421 tatcttgcca tagagcttta aacgcagttt gcgggtggcg cgccagtagg cggcgttgat
    27481 cttctccggc tgcttcagta acaccgaacg cagaatctct gcgctatcca gcgcatagct
    27541 aatcccctcc agcgagctgg cgctgataaa tcccgccgct tcaccaatca gaaaggcatt
    27601 gtccttaccg cagacaaaat cctgccagcg tgagggaaac aacacggtac atttctcact
    27661 tttcaccgct ttgccaaact ggaactgaaa ggcgttcatt ttctctttca gcgtcgtgaa
    27721 acgcgtctga ccgtctttca tgggataggc accgccaaag ataaaataac cgtctttgct
    27781 gatactccat gagtaacagt cagttatcgc attatcaaag atgcaggagt agaacggcac
    27841 cggatgtttc tctgcgaacc actgctggat agcgacatat ttacgaattt gatgatccgg
    27901 gtagagatgt cgccgcacca tcgagttggc accatcggca ccgaccagat agcgggcaga
    27961 aatatgctgc tcccaaccgt ctgcacgaaa aatgacatgc catttatcat cctcacgcca
    28021 gatttttcga cacaggctgt cgtggtaaac ctcaacgctg gcggggatca gcgatttcat
    28081 ccacaagtcg aaagcatggc gattaatatt gatatagctt cgctggtagt tacgcgtgag
    28141 cgatgcggcg acgtcgacag ttttgacgct gaaaatctgt ggattggcga tcacatcgac
    28201 aggaagcgtc agtccatcgc gaataaaaga tcgctgcgcg tccggtgcca gcagaccgcc
    28261 gcagggtttg ctgaaacctt cagtaccaca ctggtgcttt ttatccagcg cgatcacctg
    28321 cattttgcct gctaactttc gtgccaacgc cgaccctgcc gggccgaggc caataatcgc
    28381 cacgtcgaaa tgttccatct tttcactcac attcatcacg atggcgaaag actattgtct
    28441 gaaagtgaag tccttgtgaa gtatgatggc gggacccgtt ttgtatcagg accgcgccat
    28501 gaaacagata acctttgctc cccgtaatca cctgctcacc aataccaata cctggacgcc
    28561 cgacagccag tggctggtat ttgacgtgcg tccttctggc gcgtcgttta ccggcgagac
    28621 cattgagcgt gtgaatatcc ataccggcga ggtcgaggtt atctatcgcg cgtcacaggg
    28681 cgcgtacgtc ggcgtggtga ccgttcatcc gaaatcagag aaatatgttt tcatccacgg
    28741 cccggaaaat cctgatgaaa catggtatta cgacttccat catcggcgtg gagtgattgt
    28801 tgaaggcggc aaggtgagca atctcgatgc aatggatatt accgcgccat atacgccagg
    28861 agcgctgcgc ggcggcagtc atgtacatgt ttttagccca aacggtgaaa gggtgagctt
    28921 tacctataat gaccatgtaa tgcatgaact cgatccggtg ctggatttgc gaaacgtcgg
    28981 tgttgctgca ccgtttggcc cggtcaacgt acaaaagcag catccgcgtg aatacagcgg
    29041 tagccactgg tgcgtgctgg taagtaaaac cacgcccacg ccacagccag gcagtgatga
    29101 aatcaatcgt gcttatgaag aaggatgggt aggaaatcac gcactggcgt ttattggcga
    29161 cacactttcg gcaaagggcg agaaagtgcc ggagctattt atcgttgagt taccgcaaga
    29221 tgaagctggc tggaaagcgg caggtgatgc gccgttaagt ggaacggaaa caaccctgcc
    29281 tgcgccaccg cgcggcgtcg tgcagcgacg tttaaccttt acccaccatc gggcttatcc
    29341 ggggttagtc aacgtcccgc gccactgggt gcgctgtaat ccgcagggta cgcaaatcgc
    29401 gtttttaatg cgtgatgata acggcattgt gcaactgtgg cttatctcgc cacagggcgg
    29461 cgagccgcgc cagttaaccc ataacaaaac ggatattcag tctgcattta actggcatcc
    29521 gtcaggagaa tggttgggct ttgtgctgga taatcgaatt gcttgcgccc atgcgcaaag
    29581 cggcgaggtt gagtatttaa ccgaaaacca cgccaatcca ccttctgcgg acgccgtggt
    29641 cttctcgccg gatggtcaat ggctggcgtg gatggaaggc ggccagctgt ggatcaccga
    29701 aactgatcgc taaatcagtt atcaggcatt ctggccggtg gaataaccgc attggtggct
    29761 tgcgcgttgg cttcgctttt ttcaacgcgt gagcgcaccg agctgtcttt gcggaacaca
    29821 tcccacggca gtaaaagcgt gtccatcaca gcggtaaacg gcatatcgag aatcgccagc
    29881 gacttagtgc cccagttggt ttcatcgtcg ccaatcatgg tggcgctggc gcgggtgccg
    29941 ggatacgttc cttctttccc cccggtatgg gacatcacgc tggagcatcc tccgagtaat
    30001 gtcattccgc tgcatatcat gaacgctaac aacacatttc ttatcataat aaattcatct
    30061 gttgatcgtg ggtgttggcc tgatgagtta tagcgatccc ttgctgaaaa taacatcatc
    30121 attacgtcgc actgtggcgg ctatcgcact ttaacgtttc gtgctgcccc ctcagtctat
    30181 gcaatagacc ataaactgca aaaaaaagtc cgctgataag gcttgaaaag ttcatttcca
    30241 gacccatttt tacatcgtag ccgatgagga cgcgcctgat gggtgttctg gctacctgac
    30301 ctgtccattg tggaaggtct tacattctcg ctgatttcag gagctattga ttatgcgtaa
    30361 ctttgattta tccccgcttt accgttctgc tattggattt gaccgtttgt ttaaccactt
    30421 agaaaacaac cagagccaga gtaatggcgg ctaccctccg tataacgttg aactggtaga
    30481 cgaaaaccat taccgcattg ctatcgctgt ggctggtttt gctgagagcg aactggaaat
    30541 taccgcccag gataatctgc tggtggtgaa aggtgctcac gccgacgaac aaaaagagcg
    30601 cacctatctg taccagggca tcgctgaacg caactttgaa cgcaaattcc agttagctga
    30661 gaacattcat gttcgtggtg ctaacctggt gaatggtctg ctgtatatcg atcttgaacg
    30721 cgtgattccg gaagcgaaaa aaccgcgccg tatcgaaatc aactaattcc ctaaggccgc
    30781 ctggcgcggc ctgacatctc catgctcgcc gtcagggagc atatgcgaat cttcggattt
    30841 gcaggtactt actcgcttct tagaaggaga aatgactatg cgtaacttcg atttatcccc
    30901 actgatgcgt caatggatcg gttttgacaa actggccaac gcactgcaaa acgccggtga
    30961 aagccagagc ttcccgccgt acaacattga aaaaagcgac gataaccact accgcattac
    31021 ccttgcgctg gcaggttttc gtcaggaaga tttagagatt caactggaag gtacgcgcct
    31081 gagcgtaaaa ggcacgccgg agcagccaaa agaagagaaa aaatggctgc atcaagggct
    31141 tatgaatcag ccatttagcc tgagctttac gctggctgaa aatatggaag tctctggtgc
    31201 aaccttcgta aacggtttac tgcatattga tttaattcgt aatgagcctg aacccatcgc
    31261 agcgcagcgt atcgctatca gcgaacgtcc cgcgttaaat agctaactag ctattctctt
    31321 tgccccgcca ttctggtggg gctttttttg tctttcttct tcaacaatgc gttaaatttc
    31381 gcctgtttaa gatatttcgg cacgttcttt cccgtgataa tgtgcgctat aaggcaaatc
    31441 tgcttcaccg attcagccat aatccgtagc aattaaaatg ttatctcaag agaaatggac
    31501 gatgagtgat atagcattaa cggtcagtat tctggctttg gtggcagtcg tcggtttgtt
    31561 tatcggcaac gtcaaatttc gcggcatagg attaggtatt ggcggcgtgc tgtttggtgg
    31621 gatcatcgtc ggccattttg tttctcaggc ggggatgaca ttaagtagcg atatgctgca
    31681 tgttattcag gaatttggcc tgatcctgtt cgtttatacc atcgggattc aggtagggcc
    31741 gggcttcttt gcctcattgc gcgtctccgg attacgcctc aacctgtttg ctgttctgat
    31801 tgtcatcatc gggggtctgg ttaccgccat cctgcataaa ctgtttgata ttccactgcc
    31861 ggtagtgctg gggattttct ccggtgcggt aaccaatacg ccagcgctgg gggcagggca
    31921 gcagatcttg cgcgacctgg gtacaccaat ggaaatggtc gatcagatgg ggatgagtta
    31981 cgcgatggcg tatccattcg gtatttgcgg gattttgttc accatgtgga tgttgcgggt
    32041 tattttccgc gtcaatgtcg agacagaagc ccagcagcac gagtcttctc gcaccaatgg
    32101 cggcgcgctg atcaggacta tcaatattcg cgttgagaac cctaacctgc atgatttagc
    32161 cattaaagat gtaccgattc tcaacggcga caaaattatc tgctcgcgtc tgaaacgaga
    32221 agaaacccta aaagtacctt cgccagatac cattatccaa ctgggcgatt tgctgcatct
    32281 ggtggggcag ccagcggatt tacataatgc gcaactggtg attggtcagg aggtcgatac
    32341 ctcgctgtcc acgaaaggca ctgatttacg cgtcgagcgt gtggtggtca ccaatgaaaa
    32401 cgtgctcggt aaacgtattc gcgacctgca ctttaaagaa cgctatgacg ttgttatctc
    32461 gcgcctgaac cgtgccgggg tcgaactggt cgccagtggc gatatcagcc tgcagttcgg
    32521 cgatatcctc aacctggtgg ggcgtccgtc cgcaattgat gccgttgcca atgtgctggg
    32581 gaatgcgcag caaaaactgc aacaggttca gatgctgccg gtgtttattg gtatcgggct
    32641 tggcgtattg ttaggttcta ttcccgtctt tgtgccggga ttcccggccg cgttgaaact
    32701 ggggctggcg ggcggtccgc tgattatggc gttgatcctc gggcgtatcg gcagtatcgg
    32761 caagctgtac tggtttatgc cgccaagtgc caacctcgcg ctgcgggagc tggggatcgt
    32821 gctgttcctc tcggtcgttg gtctgaaatc tggtggggat tttgtgaata ccctggtcaa
    32881 tggcgaaggg ctaagctgga ttggttatgg tgcgctgatc accgccgttc cgctgattac
    32941 ggtcggcatt ctggcgcgga tgttagccaa aatgaattac ctgaccatgt gcgggatgct
    33001 ggctggctcc atgaccgatc ctccggcgct ggcatttgct aataatcttc atccaaccag
    33061 cggtgcggcg gcactctctt atgccactgt ctatccgttg gtgatgttcc tgcgcattat
    33121 caccccacaa ttactggcgg tgctcttttg gagtatcggt taactctttt ccgggtggag
    33181 tcgccgtaaa tggtactcca cctggtattc actggcattt ctgaacatta ctgaataatt
    33241 caaaaactcc ccgctctcgc tatatgacaa cgaggtgatc cgcagcagtg gcgtgtgttc
    33301 cgctaccttc atttgccgcg ccagtagtct atcggcgagc accggcgtca ggctttcata
    33361 attaccgcca atcagaatcc cgcactcttg ttcaatatat tcaaacttcg acccttcaag
    33421 atgttgcagc gataggttgc ggaacagttt taccggcata tagctgtctt ccagcatcag
    33481 cggtttccct tccacaaaac gaacgcgacg ggagaagtag atctgctcgt tgatttgaat
    33541 ccgtaactgg ctggcaatgg ccggaggcgc aggcatgatt tcaaaaatca gcacctggct
    33601 ggtgacagtt tttccctggc gttttaacac ctccaccagc ccggtcaggc tggcggtttg
    33661 atgcaataca tctttgcgca ccaggtaagt accgctaccg tggcggcgga ccaccagccc
    33721 ccacgctacc agcagatcaa tggctttacg gatggtcatc cgcgataccg caaactcttc
    33781 cgccagcttt ttttcaccgg gaagaaggct gtttagcgtg aaatctgcgg aattaagtcg
    33841 aattcttaac cgctccgcaa tgcttttgta gatcatctct agatctcttt tttgcctgca
    33901 agcccgggta atgcgcccac aagttctgct taatcgattg aaaaaacatc ttttttttaa
    33961 agatgtgttc gttgctgtgt accagtgctc acagatgtct acttttttgc gaaaacgtag
    34021 atctctaccg cccaacgaaa agcatgaaag cgatcacgaa tcccattggg tcgtcatgtt
    34081 ctgccgatcg catcttccta tcctcgctcc aggcctgccg cataaccaat caggcttcct
    34141 acttacagaa ttgagaaaag aggatgtgga aatgctcagt caaattcaac gctttggcgg
    34201 cgcgatgttc acgccagtgc tgctgtttcc cttcgccggg attgtggtgg gtcttgccat
    34261 cttgctgcaa aacccgatgt ttgtcgggga atcactgacc gatccgaaca gtttattcgc
    34321 gcaaatcgta catattattg aagagggcgg ttggacggta ttccgtaata tgccgctgat
    34381 ttttgctgtc ggtttaccca ttggccttgc taagcaagcg caggggcgag cttgtctggc
    34441 ggtgatggtg agtttcctga cctggaacta ttttatcaac gcgatgggaa tgacctgggg
    34501 aagctacttc ggcgtcgatt tcactcagga cgcggtggca ggtagcggtc tgacaatgat
    34561 ggccgggatt aaaaccctcg ataccagcat tatcggcgca attatcattt ccggcattgt
    34621 gacggcgctg cataaccgtc tgttcgataa aaaactgccg gtttttctcg gcattttcca
    34681 ggggacgtct tatgtggtga ttatcgcctt cctggtgatg atcccttgcg cctggctgac
    34741 gttgctcggc tggccaaaag tacaaatggg gattgaatct ctgcaagcgt tcctgcgttc
    34801 ggcgggtgcg cttggggtgt gggtttacac cttcctcgaa cgtattctga tcccaaccgg
    34861 tttacaccac ttcatctacg gaccgtttat ctttggtccg gcagctgttg aaggcggcat
    34921 tcagatgtac tgggcgcagc atctgcaaga gttcagtttg agcgccgagc cgctgaaatc
    34981 gttgttcccg gaaggcggtt ttgccctgca cggtaactca aaaatctttg gtgccgtggg
    35041 catttcttta gcgatgtact tcactgccgc accggaaaat cgggtaaaag tggcgggctt
    35101 gctgatcccc gcaaccttaa ccgccatgct ggtgggaatt accgaaccgc tggaatttac
    35161 cttcctgttc atttcaccgt tgctgtttgc ggtacacgcc gtgctggcgg cctcaatgtc
    35221 gaccgtaatg tatctctttg gtgtggtggg caacatgggc ggtggtttga ttgaccaggt
    35281 tttaccgcaa aactggatcc caatgttcag caaccacgcg gatatgatgc tgacccaaat
    35341 cgccattggg ttgtgcttta ccctgctgta cttcgtggtt ttccgcaccc tgattctgca
    35401 attcaacatg tgcacgccgg gacgtgaaga tgcggaagtg aaactctact caaaagccga
    35461 atacaaagcc tcgcgaggcc aaaccaccgc ggcagagcca aaaaaagagc tggatcaggc
    35521 tgccggtatc ctgcaagccc tgggcggggt cggcaatatc tccagcatca acaattgcgc
    35581 gacgcgttta cgtattgcac tgcatgacat gtcacaaacg ctggatgacg aagtctttaa
    35641 aaagctggga gcgcacggcg tcttccgtag tggcgatgcc attcaggtga tcattggttt
    35701 gcatgtatcc cagctgcgtg aacagctcga tagcttaatt aattctcatc aatcagcaga
    35761 aaatgttgcc attacggagg cagtataatg accaaattct cagtggttgt cgcaggcggt
    35821 ggaagcacct ttacgccagg catcgtgttg atgctcctgg cgaatcagga ccgtttcccg
    35881 cttcgtgcac tgaaatttta tgataacgat ggtgcgcggc aggaagtgat tgccgaagcc
    35941 tgtaaagtca tccttaaaga aaaagcgccg gacattgcgt ttagttacac caccgatcct
    36001 gaagtggcat tcagcgacgt tgattttgtc atggcgcaca tccgcgtcgg caaatacccg
    36061 atgcgcgaac tggatgaaaa aatcccgctg cgccacggcg ttgttggtca ggaaacttgc
    36121 ggacccggcg gaatagcgta cggcatgcgt tccattggcg gcgtcctgga actggtggat
    36181 tatatggaaa aatattcacc aaatgcctgg atgctcaact actccaaccc ggcagccatt
    36241 gtcgcagaag ccacgcgtcg tctgcgcccg aatgcgaaaa tcctcaacat ctgtgacatg
    36301 ccaatcggta ttgaaagccg gatggcgcaa attgttgggc tgcaagatcg caaacagatg
    36361 cgcgtgcgct actacggcct gaaccacttt ggctggtgga catcaattga agatttgcag
    36421 ggcaacgacc tgatgcccca gctgcggcaa tatgtctcta agcacggtta tgttccaccg
    36481 cagcaagata cacatactga agcgagctgg aacgacacct atgcaaaagc gcgggatgtc
    36541 caggcactgg acccggatac attgccgaac acctatctga aatattatct cttcccggat
    36601 tatgtcgttc agcattccaa ccctgaacat acccgcgcga atgaggtgat ggaacatcgc
    36661 gagaaacagg ttttcgatgc ttgccgcgcc attacggcgg caggaaattc agcggcgggc
    36721 aagctggaaa ttgacgaaca tgcgtcatac atcgtcgatc ttgcggcggc gattgccttc
    36781 aacactcagg agcggatgtt gctaattgtg cctaacaacg gggcaatcca taactttgat
    36841 gatgaagcga tggtcgaaat cccgtgtctg gtcgggcaca acggaccaga accactggtg
    36901 gtcggcgata tcccgcagtt tcagaaaggg ttaatgagtc agcaagtgac ggtggaaaaa
    36961 ctggtcgtgg acgcctggga acagcgttca tatcagcacc tgtggcaggc gattacgttg
    37021 tcgaaaacgg taccgagcgc ctcggtcgcc aaagctattc tggatgagtt gctggaggcc
    37081 aacaaagcgt actggccaga gttacgttaa ttgtgtggac tggcatccgt ggggtgctgg
    37141 tccgtattct tcagcacggc tgacggcgca taaccaaatt tatttttaaa ggctttgctg
    37201 aaatgaaagg agtcgaagaa gttgagcgta tcagcgactt cgccaaccga gttcccttgt
    37261 tgctttaata gcgatagcgc cagatccaga cgcgcatcga ggtaatattc tttcggcgtc
    37321 ttgccggtat agcgtaaaaa cagacgacgc aaccaggcct cgctacaggg gatcgtggca
    37381 gccatatcag ctacgctcca gcgttgttgt agactggcat gtaaagtggc aattaatttt
    37441 tcaatttgcc gccgttgtgg atctttttta ccgactgcgt gcataagaca aatccactga
    37501 taaataattt tcgtcagaaa agcgactgcc agattatttt ttattgcttc tggtgaagta
    37561 attaactcag caacttcggt gagttcctga ttataaactt cgccattata aataacgctt
    37621 tgctgaccaa cgggaatatc catcatactg gtgggggtaa attccatcca gtactgttcc
    37681 cagactaaac cttcacagtg ataagagtga atatccattg gctttaaaaa tataatacag
    37741 ttgccatgca gagttatttg ttcgccattc tttaaaataa ttttcccaca tccttgtacg
    37801 gtatacaccg caacccatga gttggcgata agcggtttct tcttgtcccg cggccagatc
    37861 acccggtaat gctcgtcggc gtaggtatgc cagagcgaga tcagagaaat tccgctggag
    37921 atcacatttt cgttaatcaa taagggaata ttgtacggag tttcgttttt tacatccgaa
    37981 ctttgcaatt ttccattcat tttaatatcc ctccggcgaa ttatgctcac aacctgaact
    38041 taacagaaaa caatccgttc agggatacga tgtttgtatt ttaagaatct gactgcctga
    38101 cccgacgcat tttacctctc cctatattca tgcgtccggg acataaacat aaataagggc
    38161 tatgagatga attcgttaca aatcttgagt tttgtcggtt ttacgctgct ggtggcgatc
    38221 atcacctggt ggaaggttcg caaaacagat accggatcgc aacaaggcta ttttcttgcc
    38281 ggacgttcac taaaagcgcc ggttattgcc gcttcgttaa tgttaaccaa cctttccacg
    38341 gaacaactgg ttggtctttc cgggcaggcc tacaaaagcg gcatgtcggt gatgggctgg
    38401 gaagtgactt cagcggtgac gctgatcttc ctcgcgctaa tctttttacc acgctatctg
    38461 aagcgcggca ttgccaccat ccccgatttt ctggaggaac gttatgataa aacgacgcgt
    38521 attatcatcg acttctgctt cctcattgcc accggcgtct gctttctgcc gattgttctc
    38581 tactccggcg cgttggcgct caacagcctg tttcacgtcg gggaatcgct acagatttct
    38641 cacggtgcgg ctatctggct attggtaatt ttgcttggtc tggcgggaat tttgtatgcg
    38701 gtgatcggcg gactgcgcgc aatggcagtg gcggactcca tcaacggtat tgggctggtt
    38761 attggcgggt tgatggtgcc gatatttggc ctgatcgcga tgggcaaggg cagctttatg
    38821 cagggcattg agcaactcac caccgttcac gccgagaaat taaactcagt cggtggcccg
    38881 accgatccct tgccgattgg cgcggcattt accggtttga ttctggtgaa caccttttac
    38941 tggtgtacaa atcagggcat cgtgcaacgc acgctggcgt caaaaagcct ggcggaaggg
    39001 caaaaggggg cgctgttaac ggcggtgctg aaaatgctcg acccgctggt actggtgctg
    39061 ccagggttga ttgcgtttca tctgtatcag gatctaccga aagccgacat ggcctacccg
    39121 acgctggtca ataacgttct gccagtgcca ctggtgggtt tcttcggcgc ggtgttattt
    39181 ggtgcggtga tcagtacctt caacggcttt ctgaatagcg ccagtacgtt attcagtatg
    39241 ggtatttacc gtcgcatcat taaccagaat gccgagccgc agcagctggt caccgtcggg
    39301 cgcaaatttg gtttctttat cgctatcgtt tcggtgctgg tcgcgccgtg gatcgccaac
    39361 gcgccgcagg ggctgtatag ctggatgaaa cagctcaacg gtatttacaa cgtgccgctg
    39421 gttaccatca tcattatggg ctttttcttc ccgcgcattc cagcgctggc ggcaaaagtg
    39481 gcgatgggga ttggcataat cagctacatc accatcaact atctggtgaa gttcgacttc
    39541 catttcctct atgtgctggc ctgtacgttc tgcatcaacg tggtcgtgat gctggtgatc
    39601 ggttttatca aaccgcgcgc cacgccgttc accttcaaag atgcgtttgc ggtggacatg
    39661 aaaccgtgga aaaacgtcaa gatcgcgtca attggcatcc tgttcgctat gattggcgtc
    39721 tatgccgggc tggctgaatt cggcggctac ggtacgcgct ggttagcgat gatcagttat
    39781 ttcatcgctg ccgtagtgat tgtctacctg atttttgaca gctggcggca tcgtcacgac
    39841 ccagccgtaa cctttactcc cgacgcgaag gatagcctat gaaacgcccc aattttctgt
    39901 tcatcatgac cgatacccag gccaccaata tggtcggttg ctatagcggt aagccgctga
    39961 atacgcaaaa tattgatagt ctggcggcgg aaagtattcg ctttaattcc gcctacacct
    40021 gttcaccggt ttgtacacca gcgcgcgccg ggctgtttac cggtatctac gctaaccagt
    40081 ccggcccgtg gaccaacaac gtcgcgccgg gcaaaaacat ctccactatg ggacgctact
    40141 ttaaggatgc gggctatcac acctgttaca tcggcaaatg gcatctcgac ggtcatgact
    40201 atttcggcac tggcgagtgt ccgccggagt gggacgctga ttactggttc gatggggcga
    40261 actaccttag cgaactgacg gaaaaagaga tcagcctgtg gcgcaatggc ctaaacagcg
    40321 ttgaggattt acaggcgaac catatcgacg aaaccttcac ctgggcgcac cgcatcagca
    40381 atcgggcggt agattttctg caacagcccg cgcgcgccga ggaacccttc ctgatggtgg
    40441 tttcgtatga tgagccgcat cacccgttca cctgtccggt ggagtattta gagaaatacg
    40501 ctgattttta ctacgaactt ggcgagaaat cacaggatga cctggcgaac aaaccggaac
    40561 atcaccgctt atgggcgcag gcgatgccat cgccagtcgg tgatgacggg ctttatcacc
    40621 atccgctcta ttttgcctgc aatgactttg ttgatgacca aatcggacgg gtcatcaatg
    40681 ccttaacgcc agagcaacgt gaaaatacgt gggttattta tacctccgat cacggcgaaa
    40741 tgatgggcgc acataagctg atcagtaaag gggcggcgat gtatgacgac atcacccgca
    40801 ttccgctgat catccgttcg ccgcaagggg agcggcgaca ggtcgatacg ccagtcagtc
    40861 atatcgattt actgccgaca atgatggcgc tggcagatat tgaaaaacca gagattctgc
    40921 cgggggaaaa tatccttgcc gtgaaagagc cacgcggtgt aatggtggaa tttaaccgct
    40981 acgagattga gcatgacagc tttggcggtt ttattccggt gcgttgctgg gtgacggatg
    41041 actttaaact ggtactcaac ctcttcacca gtgatgaact ttacgatcgc cgtaatgatt
    41101 caaatgaaat gcataatctg atcgatgata tccgttttgc cgacgttcgc cgcaaaatgc
    41161 atgacgcctt attggattac atggacaaaa ttcgcgatcc gttccgcagt taccaatgga
    41221 gtctgcgtcc gtggcgtaaa gatgcacgac cgcgctggat gggggcgttt cgtccacgcc
    41281 cacaagatgg ctattcgcca gtggtacgcg actatgacac cggcctaccg acacaagggg
    41341 tgaaggtgga agagaaaaaa cagaagttct gatgcattat tgctgttcct agcctacttt
    41401 ttcggcgagg aacagtttac aaggagcaac aatgaaaatt tcccgcctcg gagaagcacc
    41461 tgattatcgc ttctcgctgg ctaatgagcg tacttttctg gcgtggatcc gtaccgcact
    41521 aggctttctg gcggcggggg ttgggcttga tcaacttgcg ccagatttcg ccacgcccgt
    41581 cattcgcgaa ctgctggcgt tgttgttgtg tctgttttcc ggcgggttag cgatgtatgg
    41641 ctacctgcgc tggttacgca atgaaaaagc gatgcgtctg aaagaggacc tgccctacac
    41701 caacagctta ttaatcatca gcttaatatt gatggtcgtg gcggtgatcg ttatgggact
    41761 ggtgttgtat gccggatagc cgcaaagcca gacgcattgc cgacccaggg ctgcagccgg
    41821 agcgtacatc actggcgtgg tttcgtacca tgctgggcta cggcgcgttg atggcgttgg
    41881 ctatcaaaca caactggcac caggcgggca tgttattctg gatttcgatt ggcattctcg
    41941 ccattgtggc gctgatcctc tggcactaca cccgtaatcg caatttaatg gatgtcacga
    42001 atagcgattt ttcccaattt cacgtagtcc gtgacaaatt tttgatctcc ctcgcggtgt
    42061 tatctctcgc aatactgttt gctgtaacgc atatacatca acttatcgta tttattgaga
    42121 gagtcgcatg acaggaagtc aggtcattga tgctgaagag gacaggcata aactggttgt
    42181 agagtacaag gatgctctgc aacctgccga tttttatcac aatttcaaac aacggggtat
    42241 ccgctccgta cagcttattc cccatcttga atttgatgac cggggcgatc tgacggccgc
    42301 ttcggtgaca gcagagctgt gggggaaatt tttaattgcc ctgttcgagt gttgggtacg
    42361 ggcagatatc agtcgtattt cgattgagct ttttgacgcc accctacaaa aatggtgtgg
    42421 cagcgaaaac ccgcaaccgc gtcgtggctg ccaggcgtgc gactggcatc gcctgtgccc
    42481 gcacgctcgg gaggagacgc cagacaacgt gctttgtgcg ggctatcagg cgttttattc
    42541 ttactccgcg ccgcatatgc gggtgatgcg tgatctgata aagcagcatc gttctcccat
    42601 ggagctgatg acgatgctgc ggtgacgtga gcttaaacag gctgcccctg atgcgacatc
    42661 cgcgtcgcca gcggtagcca gcacagcacg atcaacaatc ccattaaggt catcaacaac
    42721 cccaggctgc cctgaccggt ttgcggcaac atcgcagaga gcgacgccag cacgccggaa
    42781 ccaatgtttt gtagaccgcc gaccagcgcg ccagccgtgc ccgccaggaa agggaacggc
    42841 tccatcgcgc cgctggtcgc cagcggaaac agcatcccgg caccgaaaaa gaacagcgcg
    42901 gcgggaacga gcagcgtcca gacattcatc acgccaaacc agtcggggat ccacatcagt
    42961 aagccagcca gcaggcagca gataaccgac tgccacatca acgttgagaa gcgtttatta
    43021 ggacgtccgg caaaccatgc cccaaaaaat gccgccggaa tcggcagaat aaacaaaata
    43081 ctgaccgtca tactgctcaa ccctaacacc gcgcccatca gcacgccgga gcaggcttca
    43141 aaggcggcaa tcccggccag accgccaatc agcatcagca aataacagtt aaaaccgctg
    43201 ttaccgaaaa gcgttttata actggtaagc aggcgcgtgc gcggtgcgtc gaccggacgc
    43261 gtttccggca tccagcgggc catactgaag gtcacaccgg cacaaagtac caacaaaaag
    43321 agataacagg cgcgccagtt ccacatcgta tccagcagac cgccgattag cggtgcgagc
    43381 aacggactga caagaattcc catgtttaac aggctattag catggcgcaa ctgtgtccgt
    43441 tcatataaat cacgcggcaa agtacgcgcc attacgccgc caacgccggt gcccatcccc
    43501 tgcatcgcgc tggcggcaat caatactgtc aaactggagg tcgtgaccgc gaccagcgtt
    43561 gccagcataa aaatggacat tccgacgagg atcaccggtc ggcgacccac acggtcggaa
    43621 atcgggccat aaaacagctg tgagacaccg taagtcagca gataagcgcc cattacgctc
    43681 tgcaccgccc cttcacggac gttgagatcg cgcgccatat cggcaatagc tggaatatat
    43741 atggtttgcg ccatctgacc gacggccacg agtaatacca acatcaataa caaattgacg
    43801 tttctatgcc ttttcattat cacggatgct tttataaaaa taattagaat aagtcactac
    43861 gcattcccat aaatgcggga gaggaatcta tcacattgat aaatgttagc cagatatacg
    43921 ccaggaatgg ggaattgttt agcggcagaa tatgtaaaca aaagcggcaa taaatgttgc
    43981 cgggagggat ggtagggcgg ataagatgca tcagcattgc atccgacacc aacccgcacg
    44041 ctaaatatga aaggggagcg gttacccgct cccctttggt gcgacttgaa tctgaattac
    44101 ttcaggtatt tcagaacagt atcaagcagt tgcagtgctg caacaatgag tttgaggata
    44161 agaatggcga tatccaccag gctcatacgc gtctcctgtg gttcaggagc actgccagct
    44221 gacgtacctt tccgctgcct gttgccagct gttgtgcacg cggtatctca aggagaaacg
    44281 ttgtgcttgt tgacataaca cagtgtgctc acgcggggtt aaggcgctga cggcaccacc
    44341 cgtttcagcc aggacttagt gcgccgggta acgatgcggc ccccgcataa cacattgcgt
    44401 acagtgatat tatagaagtt tactgtataa ataaacagta atatttggac aaaacgaaaa
    44461 ctgtgaacga tactcaacta tgtactaaat acgtcaaaat tcgtgccgaa attgcgcgtt
    44521 ctgcgcggaa cacgtatact ttcagtgttg acataataca gtgtgctttg cggttaccag
    44581 ccgcaggcga ctgacgaaac ctcgctccgg cggggttttt tgttacccgc aattcagtac
    44641 aaaacgtgat caacccctca attttccctt gctgaaaaat tttccattgt ctcccctgta
    44701 aagctgtgct tgtataaata ttgttaaaca caaaaccaac aaggtcccca atgactactt
    44761 ccatgctcaa cgcaaaacta ctaccaactg cgccatccgc cgcagtggtc gtcgtgcgtg
    44821 tggtggtcgt cgtcggcaat gcgccgtagg gactggaaca acacacgatt ccaaaacccc
    44881 gccggcgcaa accgggcggg gtttttcgtt taagcacctc ccggaaagtc ggcccagaag
    44941 aaaaggactg gagcatggca agttcgggca caacatcgac gcgtaagcgc tttaccggcg
    45001 cagaatttat cgttcatttc ctggaacagc agggcattaa gattgtgacg ggcattccgg
    45061 gcggttctat cctgcctgtt tacgatgcct taagccaaag cacgcaaatc cgccatattc
    45121 tggctcgcca tgaacagggc gcggggttta tcgctcaggg aatggcgcgc accgacggta
    45181 aaccggcggt ctgtatggcc tgtagcggac cgggtgcgac taacctggtg accgccattg
    45241 ccgatgcgcg gctggattcc atcccgctga tttgcatcac cggtcaggtt cctgcctcga
    45301 tgatcggcac cgacgccttc caggaagtgg acacctacgg catctctatc cccatcacca
    45361 aacacaacta tctggtcaga catatcgaag aactcccgca ggtcatgagc gatgccttcc
    45421 gcattgcgca atcaggccgc cctggcccgg tgtggataga cattcctaaa gatgtgcaaa
    45481 cggcggtttt tgagattgaa gcacagccag ctatggcaga aaaagccgcc gcacccgcct
    45541 ttagcgaaga aagcattcgt gacgcagcgg caatgattaa cgccgccaaa cgcccggtgc
    45601 tttatctggg cggcggtgtg atcaatgcgc ccgcacgggt gcgtgaactg gcagagaaag
    45661 cgcaattgcc aactaccatg accttaatgg cgctgggcat gctgccaaaa gcgaatccgc
    45721 tgtcgctggg tatgctgggg atgcacggcg tgcgcagcac caactatata ctgcaggagg
    45781 cggatctgct gattgtgctc ggtgcgcgtt ttgatgaccg ggcgattggc aaaaccgagc
    45841 agttctgccc gaatgcgaaa atcattcatg tcgatatcga ccgtgcagag ctgggcaaaa
    45901 tcaagcaacc gcacgtagcg attcaggcgg atgttgatga cgtgctggcg caattgatcc
    45961 cgctggtgga agcgcaaccg cgtgcagagt ggcaccagtt ggtggcggat ttgcagcgcg
    46021 aattcccgtg tccaatcccg aaagcgtgcg atccgttaac gcattacggc ctgatcaacg
    46081 ctgttgccgc ctgtgtcgat gacagcgcga ttatcaccac cgacgtgggt cagcatcaga
    46141 tgtggacggc gcaggcttat ccgctcaatc gcccgcgcca gtggctgacc tccggcgggc
    46201 tgggcacgat gggctttggc ctgcctgcgg cgattggcgc agcgctggcg aacccggatc
    46261 gcaaagtgtt gtgtttctcc ggcgacggca gcctgatgat gaatattcag gagatggcga
    46321 ccgccagtga aaatcagctg gatgtcaaaa tcattctgat gaacaacgaa gcgctggggc
    46381 tggtacatca gcaacagagt ctgttctaca agcagggcgt ttttgccgct acctatccgg
    46441 gaaaaatcaa ctttatgcag attgccgccg gattcggcct cgaaacctgt gatttgaata
    46501 acgaaaccga tccgcaggct gcattacagg aaatcatcaa tcgccctggc ccggcgctga
    46561 tccatgtgcg tattgatgcc gaagaaaaag tgtacccgat ggtgccgcca ggtgcggcga
    46621 atactgaaat ggtgggggaa taagccatgc aaaacacaac tcatgacaac gtgattctcg
    46681 aactcaccgt tcgcaaccat ccgggcgtaa tgacccacgt ttgtggcctt tttgcccgtc
    46741 gcgcttttaa cgttgaaggc attctctgcc tgccgattca ggacagcgac aaaagccaca
    46801 tctggctact ggtcaatgac gaccagcgtc tggagcagat gataagccaa atcgataagc
    46861 tggaagatgt ggtgaaagtg cagcgtaatc agtctgatcc gacaatgttt aacaagatcg
    46921 cggtgttttt tcagtaagga gcgacattaa accgcccggg ggggtactga tgagcgattt
    46981 ttgatagatc cgttcagata tatagggtga aattgtgcca gagaccatct caggcacaat
    47041 ttattagccc tgaatgttaa tttaagtcgc tgcaccggta atttgggggt taacagttag
    47101 ggctaaaatt tccagcgatg gtgttaaatt ctgattgctg tctataccaa tggtcatgac
    47161 cagcattcta ttaattaatg gttcatcgtg aggtatatta tggcaagccc tataatcagc
    47221 ggaacaatga tgtcaaatcc ctgcccttcc acttttttgg ataaaaatat aaatatcgct
    47281 gctgagcttg atattacaaa aaacgagaaa aaatattcac ctggcagtaa tttcgcaaaa
    47341 tggatgttac aggaaataaa gcgcttaata ctaaatatca tgtccggttc tcgcagtgtt
    47401 aataccgaaa ttcttgacta tttccaccct atgccaggca ctgaaaataa tggtaatcgt
    47461 acctggatgg cggcaactgg agaggatgag tatatcgaaa tcaaacaaac aggtgataag
    47521 tcatttaata ttactctggt tggtagagat aaacgtttac gaaaagaaac tccatattca
    47581 ggagtggctg tagcgactat tatcaaatcg ttgtctgaaa aaactgctgc gttagaaaca
    47641 cattccgctg acacggtttt gagaaaga
//
LOCUS       DADXDL010000025        46644 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.025, whole genome shotgun sequence.
ACCESSION   DADXDL010000025 DADXDL010000000
VERSION     DADXDL010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46644
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.025"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(32..922)
                     /gene="rarD"
                     /locus_tag="IRB70_001735"
     CDS             complement(32..922)
                     /gene="rarD"
                     /locus_tag="IRB70_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EamA family transporter RarD"
                     /protein_id="HBC0631656.1"
                     /translation="MDAKQTRQGVLLALAAYFIWGIAPAYFKLIYYVPADEILTHRVI
                     WSFFFMVVLMSICRQWSYLKTLIQTPQKIFMLAVSAVLIGGNWLLFIWAVNNHHMLEA
                     SLGYFINPLVNIVLGMIFLGERFRRMQWLAVILAICGVLVQLWTFGSLPIIALGLAFS
                     FAFYGLVRKKIAVEAQTGMLIETMWLLPVAAIYLFAIADSSTSHMGQNPMSLNLLLIA
                     AGIVTTVPLLCFTAAATRLRLSTLGFFQYIGPTLMFLLAVTFYGEKPGADKMVTFAFI
                     WVALAIFVMDAIYTQRRTSK"
     gene            complement(974..1441)
                     /locus_tag="IRB70_001736"
     CDS             complement(974..1441)
                     /locus_tag="IRB70_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312777.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase family protein"
                     /protein_id="HBC0631657.1"
                     /translation="MSAVLTAEQALKLVGEMFVYHMPFNRALGMELERYEKEFAQLAF
                     KNQPMMVGNWAQSILHGGVIASALDVAAGLVCVGSTLTRHETISEDELRQRLSRMGTI
                     DLRVDYLRPGRGERFTATSSLLRAGNKVAVARVELHNEEQLYIASATATYMVG"
     gene            1606..2475
                     /gene="pldA"
                     /locus_tag="IRB70_001737"
     CDS             1606..2475
                     /gene="pldA"
                     /locus_tag="IRB70_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipase A"
                     /protein_id="HBC0631658.1"
                     /translation="MRTLQGWLLPVFMLPMAVYAQEATVKEVHDAPAVRGSIIANMLQ
                     EHDNPFTLYPYDTNYIIYTQTSDLNKEAIASYDWAENARKDEVKFQLSLAFPLWRGIL
                     GPNSVLGASYTQKSWWQLSNSEESSPFRETNYEPQLFLGFATDYNFAGWTLRDVEMGY
                     NHDSNGRSDPTSRSWNRLYTRLMAENGNWLVEVKPWYVVGNTDDNPDITKYMGYYQLK
                     IGYHLGDAVLSAKGQYNWNTGYGGAELGLSYPITKHVRLYTQVYSGYGESLIDYNFNQ
                     TRVGVGVMLNDLF"
     gene            2600..4429
                     /gene="recQ"
                     /locus_tag="IRB70_001738"
     CDS             2600..4429
                     /gene="recQ"
                     /locus_tag="IRB70_001738"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026263.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBC0631659.1"
                     /translation="MAQAEVLNLESGAKQVLQETFGYQQFRPGQEEIIDTVLSGRDCL
                     VVMPTGGGKSLCYQIPALLLNGLTVVVSPLISLMKDQVDQLQANGVAAACLNSTQTRE
                     QQLDVMTGCRTGQIRLLYIAPERLMLDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRP
                     EYAALGQLRQRFPTLPFMALTATADDTTRQDIVRLLGLNDPLIQISSFDRPNIRYMLM
                     EKFKPLDQLMRYVQEQRGKSGIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNIRV
                     DVQEKFQRDDLQIVVATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPA
                     EAMLFYDPADMAWLRRCLEEKPQGQLQDIERHKLNAMGAFAEAQTCRRLVLLNYFGEG
                     RQEPCGNCDICLDPPKQYDGSTDAQIALSTIGRVNQRFGMGYVVEVIRGANNQRIRDY
                     GHDKLKVYGMGRDKSHEHWVSVIRQLIHLGLVTQNIAQHSALQLTEAARPVLRGESSL
                     QLAVPRIVALKPKAMQKSFGGNYDRKLFAKLRKLRKSIADESNVPPYVVFNDATLIEM
                     AEQMPITASEMLSVNGVGMRKLERFGKPFMALIRAHVDGDDEE"
     gene            4493..5113
                     /gene="rhtC"
                     /locus_tag="IRB70_001739"
     CDS             4493..5113
                     /gene="rhtC"
                     /locus_tag="IRB70_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709629.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine export protein RhtC"
                     /protein_id="HBC0631660.1"
                     /translation="MLMLFLTVAMVHIVALMSPGPDFFFVSQTAVSRSRKEAMMGVLG
                     ITCGVMVWAGIALLGLHLIIEKMAWLHTLIMVGGGLYLCWMGYQMLRGALKKEVVSAP
                     APQVELAKSGRSFLKGLLTNLANPKAIIYFGSVFSLFVGDNVGTTERWGIFALIIIET
                     LAWFTVVASLFALPQMRRGYQRLAKWIDGFAGALFAGFGIHLIISR"
     gene            complement(5150..6010)
                     /locus_tag="IRB70_001740"
     CDS             complement(5150..6010)
                     /locus_tag="IRB70_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000133649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rpn family recombination-promoting
                     nuclease/putative transposase"
                     /protein_id="HBC0631661.1"
                     /translation="MTEATTPHDAIFKAFLSRPETARDFIEIHLPPSLVKLCNLDTLH
                     LESSSFVEENLRQYYNDVLYSVETTKGCGYIYVLIEHQSSPDENMAFRMLRYAIATMQ
                     RHLEAGHDYLPLVIPILFYQGKRSPYPWSTNWLDGFPDPDIARDLYFHAFPLVDITLI
                     PDDEIMQHRSMAAFTLVQKHIRQRDMTTLLDKLSRLMILGQMSGQQIRMLINYMALVG
                     EAQDVRTLVHGLAQRVPQQGEELMTLAEELRRDALLNVAKAMLQRGFDLQLIMEMTGL
                     SQEDLYQLQS"
     gene            complement(6169..6789)
                     /gene="rhtB"
                     /locus_tag="IRB70_001741"
     CDS             complement(6169..6789)
                     /gene="rhtB"
                     /locus_tag="IRB70_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine/homoserine lactone efflux protein"
                     /protein_id="HBC0631662.1"
                     /translation="MTLEWWFAYLLTSIILSLSPGSGAINTMTTSLNHGYRGAVASIA
                     GLQTGLAIHIVLVGVGLGTLFSRSVIAFEVLKWAGAAYLIWLGIQQWRAAGAIDLKSL
                     ASTQSRRHLFQRAVFVNLTNPKSIVFLAALFPQFIMPQQPQLMQYIVLGVTTIVVDII
                     VMIGYATLAQRIALWIKGPKQMKALNKIFGSLFMLVGALLASARHA"
     gene            6900..7922
                     /gene="pldB"
                     /locus_tag="IRB70_001742"
     CDS             6900..7922
                     /gene="pldB"
                     /locus_tag="IRB70_001742"
                     /EC_number="3.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipase L2"
                     /protein_id="HBC0631663.1"
                     /translation="MFQQQKDWETRENAFAAFTMGLLTDFWRQRDEAEFTGVDDIPVR
                     FVRFRAQHHDRVVVICPGRIESYVKYAELAYDLFHLGFDVLIIDHRGQGRSGRLLADP
                     HLGHVNRFNDYVDDLAAFWQQEVQPGPWRKRYILAHSMGGAISTLFLQRHPGVCDAIA
                     LTAPMFGIVIRMPSFMARQILNWAEAHPRFRDGYAIGTGRWRALPFAINVLTHSRQRY
                     RRNLRFYADDPTIRVGGPTYHWVRESILAGEQVLAGAGDDATPTLLLQAEEERVVDNR
                     MHDRFCELRTAAGHPVEGGRPLVIKGAYHEILFEKDAMRSVALHAIVDFFNRHNSPSG
                     NRSTEV"
     gene            7930..8730
                     /gene="yigL"
                     /locus_tag="IRB70_001743"
     CDS             7930..8730
                     /gene="yigL"
                     /locus_tag="IRB70_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar/pyridoxal phosphate phosphatase YigL"
                     /protein_id="HBC0631664.1"
                     /translation="MYQVVASDLDGTLLSPDHTLSPYAKETLKLLTARGINFVFATGR
                     HHVDVGQIRDNLEIKSYMITSNGARVHDLDGNLIFAHNLDRDIASDLFGVVNDNPDII
                     TNVYRDDEWFMNRHRPEEMRFFKEAVFKYALYEPGLLEPEGVSKVFFTCDSHEKLLPL
                     EQAINARWGDRVNVSFSTLTCLEVMAGGVSKGHALEAVAKKLGYSLKDCIAFGDGMND
                     AEMLSMAGKGCIMGSAHQRLKDLHPELEVIGTNAEDAVPHYLRKLYLS"
     gene            8806..9705
                     /gene="bioP"
                     /locus_tag="IRB70_001744"
     CDS             8806..9705
                     /gene="bioP"
                     /locus_tag="IRB70_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter"
                     /protein_id="HBC0631665.1"
                     /translation="MALLIITTILWAFSFSFYGEYLAGHVDSYFAVLVRVGLAALVFL
                     PFLRTRGNSLKTVGLYMLVGAMQLGVMYMLSFRAYLYLTVSELLLFTVLTPLYITLIY
                     DIMSKRRLRWGYAFSALLAVIGAGIIRYDQVTDHFWTGLLLVQLSNITFAIGMVGYKR
                     LMETRPMPQHNAFAWFYLGAFLVAVIAWFLLGNAQKMPQTTLQWGILVFLGVVASGIG
                     YFMWNYGATQVDAGTLGIMNNMHVPAGLLVNLAIWHQQPHWPTFITGALVILASLWVH
                     RKWVAPRSSQTADDRRRDCALNE"
     gene            complement(9593..10546)
                     /gene="metR"
                     /locus_tag="IRB70_001745"
     CDS             complement(9593..10546)
                     /gene="metR"
                     /locus_tag="IRB70_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MetR"
                     /protein_id="HBC0631666.1"
                     /translation="MIEVKHLKTLQALRNCGSLAAAAATLHQTQSALSHQFSDLEQRL
                     GFRLFVRKSQPLRFTPQGEILLQLANQVLPQISQALQACNEPQQTRLRIAIECHSCIQ
                     WLTPALENFHKNWPQVEMDFKSGVTFDPQPALQQGELDLVMTSDILPRSGLHYSPMFD
                     YEVRLVLAPDHPLAAKTRITPEDLASETLLIYPVQRSRLDVWRHFLQPAGVSPSLKSV
                     DNTLLLIQMVAARMGIAALPHWVVESFERQGLVVTKTLGEGLWSRLYAAVRDGEQRQP
                     ITEAFIRSARNHACDHLPFVKSAERPTYDAPTVRPGSPARL"
     gene            10664..12925
                     /gene="metE"
                     /locus_tag="IRB70_001746"
     CDS             10664..12925
                     /gene="metE"
                     /locus_tag="IRB70_001746"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBC0631667.1"
                     /translation="MTILNHTLGFPRVGLRRELKKAQESYWAGNSTREELLAVGRELR
                     ARHWDQQKQAGIDLLPVGDFAWYDHVLTTSLLLGNVPARHQNKDGSVDIDTLFRIGRG
                     RAPTGEPAAAAEMTKWFNTNYHYMVPEFVKGQQFKLTWTQLLEEVDEALALGHKVKPV
                     LLGPVTWLWLGKVKGEQFDRLSLLNDILPVYQQVLAELAKRGIEWVQIDEPALVLELP
                     QAWLDAYKPAYDALQGQVKLLLTTYFEGVTPNLDTITALPVQGLHVDLVHGKDDVAEL
                     HKRLPSDWLLSVGLINGRNVWRADLTEKYAQIKDIVGKRDLWVASSCSLLHSPIDLSV
                     ETRLDAEVKSWFAFALQKCHELALLRDALNSGDTAALAEWSAPIQARRHSTRVHNPAV
                     EKRLAAITAQDSQRANVYEVRAEAQRARFKLPAWPTTTIGSFPQTTEIRTLRLDFKKG
                     NLDANNYRTGIAEHIKQAIVEQERLGLDVLVHGEAERNDMVEYFGEHLDGFVFTQNGW
                     VQSYGSRCVKPPIVIGDVSRPAPITVEWAKYAQSLTDKPVKGMLTGPVTILCWSFPRE
                     DVSRETIAKQIALALRDEVADLEAAGIGIIQIDEPALREGLPLRRSDWDVYLQWGVEA
                     FRINAAVAKDDTQIHTHMCYCEFNDIMDSIAALDADVITIETSRSDMELLESFEEFDY
                     PNEIGPGVYDIHSPNVPSVEWIEALLKKAAKRIPAERLWVNPDCGLKTRGWPETRAAL
                     ANMVQAAQNLRRG"
     gene            complement(13019..13915)
                     /locus_tag="IRB70_001747"
     CDS             complement(13019..13915)
                     /locus_tag="IRB70_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0631668.1"
                     /translation="MFISDETLRVIHLVARHQSITTAAEQLNKVPSAISYTIKKAEES
                     LGVELFIRKGRYIELSPAGSYFIEHSKTILGDLEALKRNTVLIHDGIERELTIAVNNI
                     IPGDLLVAFIRDFERQFTSTTLTVDLEVYNGCWDALYSKRADLVYGAPHAVPSSEGII
                     SEPVGQMEWDFVVSPLHPLAAKRHPLENSELHHYPAVCIRDTSVNFPPMQAWLLEGQK
                     PIFVPDFATAIALIEQNVGIGYIPHHLALPLLNSGKLLKKPMREHKHATKLFLAARSD
                     GMGKACQWCIEYLRNPQLIFCS"
     gene            complement(13993..15216)
                     /locus_tag="IRB70_001748"
     CDS             complement(13993..15216)
                     /locus_tag="IRB70_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020234945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBC0631669.1"
                     /translation="MRKKEENLNTASGLRIAMILLGIAVTPVLLSSSSLGNQLSSSSL
                     ISVVLLGGVILTLLSAITISVGEKARLPTYGIVKYSFGEKGAIAINILMAISLFGWIA
                     VTANMFGHSVHDLLAQHGLEVPLALLVAAGCVIFVASTAFGFTVLGKIAQVAVPVIAL
                     VLCYILYVATHTEVAVPAAIVEMNTGVAVSTVVGTIIVLVATLPDFGSFVHNRKHALI
                     AAGVTFLVAYPLLYWAGATPSAISGQGSLLGAMAVFGAVLPAALLLIFACVTGNAGNM
                     FQGTLVVSTLLTRFPKWQITVALGILSAIVGSMDIMAWFIPFLLFLGIATPPVAGIYI
                     ADFFLYRRNGYQESVLAQESQIKVLTFAAWIIGAAVGFMTVKGLFTLTTIPSVDSILV
                     ACIAYAILSRASQHR"
     gene            complement(15242..15631)
                     /locus_tag="IRB70_001749"
     CDS             complement(15242..15631)
                     /locus_tag="IRB70_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000214032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl-tRNA amidotransferase"
                     /protein_id="HBC0631670.1"
                     /translation="MTTTLLAVNGTLMRGLELNPNMQKAGGIFVREDRTDAHYRLWSI
                     NDRHPGMIRVNEGGTHVDVEIWQLPLASFAALLMSEPAGLAIGKIKLADGSEVLGVLA
                     ENWLTEGQREITELGSWRKYTGHFHTV"
     gene            complement(15648..16604)
                     /gene="arcC"
                     /locus_tag="IRB70_001750"
     CDS             complement(15648..16604)
                     /gene="arcC"
                     /locus_tag="IRB70_001750"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBC0631671.1"
                     /translation="MVKPLAVVAVGGNALIQDEQRNSIPDQYVAVMESVQHIVDMVEA
                     GWDLVLTHGNGPQVGFILRRSELASNEVSPVPLDYAVGDTQGAIGYMFQKALHNELAR
                     RGINKPVIALVTQTRVSPHDDAFASPSKPIGAFLDEATAQQRQQQLGWTLMEDAGRGW
                     RRTVPSPAPLEIIEHDTIAHLVRQGYLVIACGGGGIPVVRDGQQLKGVEAVIDKDLAS
                     ALLASQLGADLLVIPTGVEKVAINFGTPQQQWLDAISVAEAQTLLREGQFGVGSMQPK
                     VEAIVDFINASQQQGKQASGLITSPQTIKAALAHQSGTWITL"
     gene            complement(16597..18021)
                     /locus_tag="IRB70_001751"
     CDS             complement(16597..18021)
                     /locus_tag="IRB70_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HBC0631672.1"
                     /translation="MNTLFNQPLKVVNAGLHSFADNIQHAGGSAIALNWQPPAQGDID
                     AGLDLASLLRHPLVENANQIAMTRYLEAQPVLVDVMLAKEAIPAMAEQKRILHSGPPI
                     AWEEMCGPVKGAIIGAMLYEGWATSQQDAENQINAGEIDLAPCHHYHAVGPMAGIISP
                     SMPLWVVENKTNGHRTFSNFNEGLGKVLRFGANNDEVLNRLAWMRDELAPAMKAAIAQ
                     HGELELKPLMAQALHMGDEVHNRNAAATGLLIKRLLPALLACSLPQEHIQRVVAFITG
                     NDHFFLNLSMAACKAMMDAAANVPFSSMVTVMARNGVNFGIRLSGTGDRWFQAPANAV
                     EGLFFPGFGVDDAAADLGDSAITETAGVGGFAMASSPAIVKFVGGTPADATNNSRRMQ
                     AVTLGGNPAFTLPALNFAPTAAGIDARKVTDRGILPVINTGIAHKQAGVGQIGAGITT
                     APMACFVAAVRALAEIVAKENHHG"
     gene            complement(18018..19577)
                     /gene="fdrA"
                     /locus_tag="IRB70_001752"
     CDS             complement(18018..19577)
                     /gene="fdrA"
                     /locus_tag="IRB70_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000865643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HBC0631673.1"
                     /translation="MKVKYKVFSNLYQDSVSLMQISAQISKLPGIQQASVVMGTPNNL
                     EQLRDAGLGNEINASPNDLVIAVMGEEDICNEALVLAQQRLTSKPDDETDSGIKSPEK
                     VSLEMALEAEPEANLALISVPGDYAAAEAIKALNLGMNVMMFSDNVSIVQEKSIKTLA
                     RERQRIVMGPDCGTAIVNGIPLGFANVVKRGAIGVIGASGTGLQEVTCRIDQLGAGIS
                     QALGTGGHDLSEEIGGISMLFALDALAQDDETRVIVLISKPPSPIVARTILERAEACG
                     KPVVVNFLGANPHDLARPNITAATTLASAANIAVALLNDQPIPTIETEISCDDLTMLQ
                     NACQRLPAHRQAIRGVFAGGTFCYEAQLICQQKGFSAASNTPVAGNRALANIWQSEDH
                     TLIDMGDDDFTRGKPHPMIDPTLRNQRLLNELNDSHTAVVLFDLVLGYGASATPASEL
                     LDQLSHIDMNNAPLLIAHVCGTEADSQIRSQQISALQNAGIIIASSNAQAALWASAVA
                     QTQLQKKGLNA"
     gene            complement(19672..20532)
                     /locus_tag="IRB70_001753"
     CDS             complement(19672..20532)
                     /locus_tag="IRB70_001753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001374637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HBC0631674.1"
                     /translation="MVQVTLCASSLGYLFPQNETQDLRLHSAFKHAVNLYSDAGTFIT
                     LLCAQTYLNLPDAARVWLPECWDWRREIAHSDPIQLTPGLLRTPRFCVALENATLWQS
                     PFVGGMLTLEAFPLVFQHYPTMASQRLLFCLEHNVQSTLHLPDSLTHQGLAIMEHPDA
                     LERQVPQLIGFGKGLTPDGDDYLLGYLAALWLWQLPAPLADHQYRLQQVIDQHAHNTT
                     DISRHYLERALQGHFSEPICQLLAQLVGSASAMTIASCAEQVMQFGATSGVDCLAGML
                     HGFRTLNTMN"
     gene            complement(20538..21206)
                     /locus_tag="IRB70_001754"
     CDS             complement(20538..21206)
                     /locus_tag="IRB70_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBC0631675.1"
                     /translation="MTQSIFQAQPFELPFDPRTTALVMIDMQRDFVEAGGFGEALGND
                     VSRVRTAIAPCTEVLAAARQKGIMVIHTREGHRADLSDCPPAKLTRGGKTFIGEPGPM
                     GRILVRGEAGHDIIPELYPVAGEPVIDKPGKGAFYQTDLHLILQNHGIKTLIVCGVTT
                     EVCVTTTVREANDRGYECIIPEDCVGSYFPEFQKYALEMIKAQGAIFGWVTDSKAIIA
                     GLEG"
     gene            complement(21463..22272)
                     /locus_tag="IRB70_001755"
     CDS             complement(21463..22272)
                     /locus_tag="IRB70_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBC0631676.1"
                     /translation="MATTQQSGFAPAASPLASTIVQTPDDAIVAGFTSIPSQGDNMPA
                     YHARPKQSDGPLPVVIVVQEIFGVHEHIRDICRRLALEGYLAIAPELYFREGDPNDFA
                     DIPTLLSGLVAKVPDSQVLADLDHVASWASRNGGDVHRLMITGFCWGGRITWLYAAHN
                     PQLKAAVAWYGKLTGDKTLNSPKQPVDIATDLNAPVIGLYGGQDNSIPQESVETMRQA
                     LRAANAKAEIIVYPDAGHAFNADYRPSYHAESAKDGWQRMLEWFTQYGVKK"
     gene            22534..23298
                     /gene="udp"
                     /locus_tag="IRB70_001756"
     CDS             22534..23298
                     /gene="udp"
                     /locus_tag="IRB70_001756"
                     /EC_number="2.4.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001593007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine phosphorylase"
                     /protein_id="HBC0631677.1"
                     /translation="MSKSDVFHLGLTKNDLQGATLAIVPGDPDRVEKIAALMDKPVKL
                     ASHREFTTWRAELDGKPVIVCSTGIGGPSTSIAVEELAQLGIRTFLRIGTTGAIQPHI
                     NVGDVLVTTASVRLDGASLHFAPLEFPAVADFECTTALVEAAKSIGATTHVGVTASSD
                     TFYPGQERYDTYSGRVVRHFKGSMEEWQAMGVMNYEMESATLLTMCASQGLRAGMVAG
                     VIVNRTQQEIPNAETMKQTESHAVKIVVEAARRLLK"
     gene            complement(23332..24822)
                     /locus_tag="IRB70_001757"
     CDS             complement(23332..24822)
                     /locus_tag="IRB70_001757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter permease"
                     /protein_id="HBC0631678.1"
                     /translation="MFESELLTQGFSTLLNNPQALLFATFGVMLGIVIGALPGLTATM
                     GVAILLPFTYGMEPVSGLLMICGVFFGGVYGGSITAILLKIPGTPAAAATAIDGYELT
                     KQGKAGLALSAATFSSFSGGTLSIIVLMFLSPVLASWALKFSASESFALATFGLSIIA
                     SISGESLIKGLIAGVGGLLIATIGLDPMGGFPRFTGGFVELMNVPFIPVMIGLFAASE
                     AFRSMEQNQQIRQGAKVAIGSLLLPWQTLRRIALTILRSSGLGVFIGMIPGAGADIAA
                     FVAYNETRRFSKTPENFGKGEIKAVASCEAGANGCTGGALLPMLTLGIPGDAVTAIML
                     GALTLQGMQPGPLMFTDHGDMVYTLFVGMIFCYFMLLVLGLLSLKVIGNVVKIPGNIL
                     TPMILALCVVGTYALNNSLFDVGIMLIAGVVGYFMQKGGYPASPVVLALIMGPMAESN
                     FRRALSLSGGSLDFLYTRPITLALLTLAAFTLLTPIIRKIMRLRRQ"
     gene            complement(24835..25341)
                     /locus_tag="IRB70_001758"
     CDS             complement(24835..25341)
                     /locus_tag="IRB70_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001596577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter TctB
                     family protein"
                     /protein_id="HBC0631679.1"
                     /translation="MNTKQSVAQLAVPHRKRLSSTMVVALLLCVVAGAVMINAADFPA
                     TAIETDPGASAFPTFYACALIVLAVLLVIRDLLQAKPASCANAQEKPAFRKTATGIAA
                     TAFYIVTMSYCGYLITTPVFLIVIMTLMGYRRWVLTPGIALLLTAILWLLFVEALQVP
                     LPVGTFFE"
     gene            complement(25358..26332)
                     /locus_tag="IRB70_001759"
     CDS             complement(25358..26332)
                     /locus_tag="IRB70_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016233692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tripartite tricarboxylate transporter substrate
                     binding protein"
                     /protein_id="HBC0631680.1"
                     /translation="MIKHLTLPKKMAAMVLLAGAALSTAPVQAASWPTKQIELVVPYA
                     AGGGTDLVARAFADAAKNHLPVSIGVINKPGGGGAIGLSEIAAARPNGYKIGLGTVEL
                     TTLPSLGMVRFKTSDFKPIARLNADPAAITVRADAPWNSYDEFMTYAKANPGKVRIGN
                     SGTGAIWHLAAAALEDKTGAKFSHVPYDGAAPAITGLLGGHIEAVSVSPGEVINHVKG
                     GKLKTLVVMADERMKTMPDVPTLKEKGVDLSIGTWRGLIVSQKTPQDVVDVLAKAAKE
                     TAEEPAFQDALQKLNLNYAWLDAASFQTQISEQEKYFDELLTRLGLKK"
     gene            complement(26357..26986)
                     /locus_tag="IRB70_001760"
     CDS             complement(26357..26986)
                     /locus_tag="IRB70_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001116470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-6-phosphogalactonate aldolase"
                     /protein_id="HBC0631681.1"
                     /translation="MPFKTLLQKTGLVAILRGVKPDEIVAIGEKLYAAGFRLIEIPMN
                     SPEALQSISLLRDALPKDCLVGAGTVLSVEQVVAVKEAGGQIIVMPHCDTAVIRRARA
                     LGMYCAPGVATPTEAFAAIEHGANAIKLFPAEQITPEVTKAWRAVIPQSVPMLPVGGI
                     TPETMARYLSHGANGFGLGSALYHPGMTPEQVYENAVLFMNAWNNLNSN"
     gene            complement(26976..27980)
                     /locus_tag="IRB70_001761"
     CDS             complement(26976..27980)
                     /locus_tag="IRB70_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygalactonokinase"
                     /protein_id="HBC0631682.1"
                     /translation="MPGAPSFIALDWGTSSLRAWRFGESPNPQEKREFPWGIMKLPSQ
                     AATREDAFHDTFLRVCGDWLAQTPCPVLACGMLGSAQGWQPAAYLPCPVTLEGLAKQL
                     TPVIHQQQTMLHIIPGVIKEGEMPEVMRGEETQIFGAISMEPALQNAIHQGMPVLIGL
                     PGTHAKWAVVENNTITDFRTFMTGELFDVLSRHSILGATMHPGDEPHWDAFTHGLTAA
                     QEHHQTGLLSTLFSTRSRLLTSNLTSSSQGDYLSGLLIGHELCGLASSLLRDLPATTP
                     IALIGSANLNSRYSQAFSHVFPDRQIHAIPNATEQGLWRIAHAAGLLSTNARECTHAI
                     "
     gene            complement(28004..28771)
                     /locus_tag="IRB70_001762"
     CDS             complement(28004..28771)
                     /locus_tag="IRB70_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBC0631683.1"
                     /translation="MAETSSTTAGAQTLLRGLAVLNAVYNGCHDLKSIGEFTGTTRST
                     THRLVTVLVEQRYLRHVPTQGYQLGAKLIEFGARALESTSLYEIAQPVLQRLARYTLD
                     TVHLGIVEGDEVLYLEKINSQRGLEMRSRPGHRMPLAITGIGKALILNRTEEEWRTLF
                     KTCGDETKLGAFIQNMRRYAASGFAFDLEENEPTIRCVAAPVYNARDEIVAAISVAST
                     TTYMSLARLEELAPYVKSCAEEISAELGWGKHVRKDK"
     gene            28988..30415
                     /gene="rmuC"
                     /locus_tag="IRB70_001763"
     CDS             28988..30415
                     /gene="rmuC"
                     /locus_tag="IRB70_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA recombination protein RmuC"
                     /protein_id="HBC0631684.1"
                     /translation="MDFSIMVYAVIALVGVAIGWLFASYQHAQQKAEQLAEREEMVAE
                     LSAAKQQITQSEHWRAECELLNNEVRSLQSINTSLEADLREVTTRMEAAQQHADDKIR
                     QMINSEQRLSEQFENLANRIFEHSNRRVDEQNRQSLNSLLSPLREQLDGFRRQVQDSF
                     GKEAQERHTLTHEIRNLQQLNAQMAQEAINLTRALKGDNKTQGNWGEVVLTRVLEASG
                     LREGYEYETQVSIENDARSRMQPDVIVRLPQGKDVVIDAKMTLVAYERYFNAEDDYTR
                     ESALQEHIASVRNHIRLLGRKDYQQLPGLRTLDYVLMFIPVEPAFLLALDRQPELITE
                     ALKNNIMLVSPTTLLVALRTIANLWRYEHQSRNAQQIADRASKLYDKMRLFIDDMSAI
                     GQSLDKAQDNYRQAMKKLSSGRGNVLAQAEAFRGLGVEIKREINPDLAEQAVSQDEEY
                     RLRSVPEQPNDEAYQRDDEYNQQSR"
     gene            30510..31265
                     /gene="ubiE"
                     /locus_tag="IRB70_001764"
     CDS             30510..31265
                     /gene="ubiE"
                     /locus_tag="IRB70_001764"
                     /EC_number="2.1.1.163"
                     /EC_number="2.1.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional demethylmenaquinone
                     methyltransferase/2-methoxy-6-polyprenyl-1,4-benzoquinol
                     methylase UbiE"
                     /protein_id="HBC0631685.1"
                     /translation="MVDKSQETTHFGFQTVAKEQKADMVAHVFHSVASKYDVMNDLMS
                     FGIHRLWKRFTIDCSGVRRGQTVLDLAGGTGDLTAKFSRLVGETGKVVLADINESMLK
                     MGREKLRNIGVIGNVEYVQANAEALPFPDNTFDCITISFGLRNVTDKDKALRSMYRVL
                     KPGGRLLVLEFSKPIIEPLSKAYDAYSFHVLPRIGSLVANDADSYRYLAESIRMHPDQ
                     DTLKAMMQDAGFESVDYYNLTAGVVALHRGYKF"
     gene            31279..31884
                     /gene="ubiJ"
                     /locus_tag="IRB70_001765"
     CDS             31279..31884
                     /gene="ubiJ"
                     /locus_tag="IRB70_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis protein UbiJ"
                     /protein_id="HBC0631686.1"
                     /translation="MPFKPLVTAGIESLLNTFLYRSPALKTARSRLLGKVLRVEVKGF
                     STSLILVFSERQVDVLGEWAGDADCTVIAYASVLPKLRDRQQLAALIRSGELEVQGDI
                     QVVQNFVALADLAEFDPAELLAPYTGDIAAEGISKAMRGGAKFLHHGIKRQQRYVAEA
                     ITEEWRMAPGPLEVAWFAEETAAVERAVDALTKRLEKLEAK"
     gene            31881..33521
                     /gene="ubiB"
                     /locus_tag="IRB70_001766"
     CDS             31881..33521
                     /gene="ubiB"
                     /locus_tag="IRB70_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ubiquinone biosynthesis regulatory protein
                     kinase UbiB"
                     /protein_id="HBC0631687.1"
                     /translation="MTPGEVRRLYFIIRTFLSYGLDELIPKMRITLPLRLWRYSLFWM
                     PNRHKDKPLGERLRLALQELGPVWIKFGQMLSTRRDLFPPHIADQLALLQDKVAPFDG
                     KLAKQQIEAAMGGLPVEAWFDDFEIKPLASASIAQVHTARLKSNGKEVVIKVIRPDIL
                     PVIKADLKLIYRLARWVPRLLPDGRRLRPTEVVREYEKTLIDELNLLRESANAIQLRR
                     NFEDSPMLYIPEVYPDYCSEGMMVMERIYGIPVSDVAALEKNGTNMKLLAERGVQVFF
                     TQVFRDSFFHADMHPGNIFVSYEHPENPKYIGIDCGIVGSLNKEDKRYLAENFIAFFN
                     RDYRKVAELHVDSGWVPPDTNVEEFEFAIRTVCEPIFEKPLAEISFGHVLLNLFNTAR
                     RFNMEVQPQLVLLQKTLLYVEGVGRQLYPQLDLWKTAKPFLESWIKDQVGIPALVRAF
                     KEKAPFWVEKMPELPELVYDSLRQGKYLQHSVDKIARELQSNHVRQGQSRYFLGIGAT
                     LVLSGTFLLVSRPEWGLMPGWLMAGGLIAWFVGWRKTR"
     gene            33600..33869
                     /gene="tatA"
                     /locus_tag="IRB70_001767"
     CDS             33600..33869
                     /gene="tatA"
                     /locus_tag="IRB70_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatA"
                     /protein_id="HBC0631688.1"
                     /translation="MGGISIWQLLIIAVIVVLLFGTKKLGSIGSDLGASIKGFKKAMS
                     DDEPKQDKTSQDADFTAKTIADKQADTNQEQAKTEDAKRHDKEQV"
     gene            33873..34388
                     /gene="tatB"
                     /locus_tag="IRB70_001768"
     CDS             33873..34388
                     /gene="tatB"
                     /locus_tag="IRB70_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatB"
                     /protein_id="HBC0631689.1"
                     /translation="MFDIGFSELLLVFIIGLVVLGPQRLPVAVKTVAGWIRALRSLAT
                     TVQNELTQELKLQEFQDSLKKVEKASLTNLTPELKASMDELRQAAESMKRSYVANDPE
                     KASDEAHTIHNPVVKDNEAAHEGVTPAAAQTQASSPEQKPETTPEPVVKPAADAEPKT
                     AAPSPSSSDKP"
     gene            34391..35167
                     /gene="tatC"
                     /locus_tag="IRB70_001769"
     CDS             34391..35167
                     /gene="tatC"
                     /locus_tag="IRB70_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sec-independent protein translocase subunit
                     TatC"
                     /protein_id="HBC0631690.1"
                     /translation="MSVEDTQPLITHLIELRKRLLNCIIAVIVIFLCLVYFANDIYHL
                     VSAPLIKQLPQGSTMIATDVASPFFTPIKLTFMVSLILSAPVILYQVWAFIAPALYKH
                     ERRLVVPLLVSSSLLFYIGMAFAYFVVFPLAFGFLANTAPEGVQVSTDIASYLSFVMA
                     LFMAFGVSFEVPVAIVLLCWMGITSPEDLRKKRPYVLVGAFVVGMLLTPPDVFSQTLL
                     AIPMYCLFEIGVFFSRFYVGKGRNREEENDAEAESEKTEE"
     gene            35209..35991
                     /gene="tatD"
                     /locus_tag="IRB70_001770"
     CDS             35209..35991
                     /gene="tatD"
                     /locus_tag="IRB70_001770"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709645.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3'-5' ssDNA/RNA exonuclease TatD"
                     /protein_id="HBC0631691.1"
                     /translation="MFDIGVNLTSSQFAKDRDDVVARAFDAGVNGLLITGTNLRESQQ
                     AQKLARQYSSCWSTAGVHPHDSSQWQAATEEAIIELAAQPEVVAIGECGLDFNRNFST
                     PEEQERAFVAQLRIAAELNMPVFMHCRDAHERFMTLLEPWLDKLPGAVLHCFTGTREE
                     MQACVARGIYIGITGWVCDERRGLELRELLPLIPAEKLLIETDAPYLLPRDLTPKPSS
                     RRNEPAHLPHILQRIAHWRGEDAAWLAATTDANVKTLFGIAF"
     gene            complement(35988..36476)
                     /gene="rfaH"
                     /locus_tag="IRB70_001771"
     CDS             complement(35988..36476)
                     /gene="rfaH"
                     /locus_tag="IRB70_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription/translation regulatory transformer
                     protein RfaH"
                     /protein_id="HBC0631692.1"
                     /translation="MQSWYLLYCKRGQLQRAQEHLERQAVNCLAPMITLEKIVRGKRT
                     AVSEPLFPNYLFVEFDPEVIHTTTINATRGVSHFVRFGASPAIVPSAVIHQLSVYKPK
                     DIVDPATPYPGDKVIITEGAFEGFQAIFTEPDGEARSMLLLNLINKEIKHSVKNTEFR
                     KL"
     gene            36643..38136
                     /gene="ubiD"
                     /locus_tag="IRB70_001772"
     CDS             36643..38136
                     /gene="ubiD"
                     /locus_tag="IRB70_001772"
                     /EC_number="4.1.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-polyprenylbenzoate decarboxylase"
                     /protein_id="HBC0631693.1"
                     /translation="MDAMKYNDLRDFLTLLEQQGELKRITLPVDPHLEITEIADRTLR
                     AGGPALLFENPKGYSMPVLCNLFGTPKRVAMGMGQEDVSALREVGKLLAFLKEPEPPK
                     GFRDLFDKLPQFKQVLNMPTKRLRGAPCQQKIVSGDDVDLNRIPIMTCWPEDAAPLIT
                     WGLTVTRGPHKERQNLGIYRQQLIGKNKLIMRWLSHRGGALDYQEWCAAHPGERFPVS
                     VALGADPATILGAVTPVPDTLSEYAFAGLLRGTKTEVVKCISNDLEVPASAEIVLEGY
                     IEQGETAPEGPYGDHTGYYNEVDSFPVFTVTHITQREDAIYHSTYTGRPPDEPAVLGV
                     ALNEVFVPILQKQFPEIVDFYLPPEGCSYRLAVVTIKKQYAGHAKRVMMGVWSFLRQF
                     MYTKFVIVCDDDVNARDWNDVIWAITTRMDPARDTVLVENTPIDYLDFASPVSGLGSK
                     MGLDATNKWPGETQREWGRPIKKDPDVVAHIDAIWDELAIFNNGKSA"
     gene            38182..38883
                     /gene="fre"
                     /locus_tag="IRB70_001773"
     CDS             38182..38883
                     /gene="fre"
                     /locus_tag="IRB70_001773"
                     /EC_number="1.5.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-flavin reductase"
                     /protein_id="HBC0631694.1"
                     /translation="MTTLSCKVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMDER
                     DKRPFSMASTPDEKGFIELHIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRDDE
                     ERPMILIAGGTGFSYARSILLTALARNPNRDITIYWGGREEQHLYDLSELEALSLKHP
                     GLQVVPVVEQPEAGWRGRTGTVLTAVLQDHGTLAEHDIYIAGRFEMAKIARDLFCSER
                     NAREDRLFGDAFAFI"
     gene            complement(39074..40237)
                     /gene="fadA"
                     /locus_tag="IRB70_001774"
     CDS             complement(39074..40237)
                     /gene="fadA"
                     /locus_tag="IRB70_001774"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadA"
                     /protein_id="HBC0631695.1"
                     /translation="MEQVVIVDAIRTPMGRSKGGAFRHVRAEDLSAHLMRSLLARNPA
                     LEAAALDDIYWGCVQQTLEQGFNIARNAALLAEVPHSVPAVTVNRLCGSSMQALHDAA
                     RMIMTGDAQACLVGGVEHMGHVPMSHGVDFHPGLSRNVAKAAGMMGLTAEMLARMHGI
                     SREMQDAFAARSHARAWAATQSGAFKNEIIPTGGHDADGVLKQFNYDEVIRPETTVEA
                     LATLRPAFDPVSGTVTAGTSSALSDGAAAMLVMSESRARELGLKPRARVRSMAVVGCD
                     PSIMGYGPVPASKLALKKAGLSASDIGVFEMNEAFAAQILPCIKDLGLMEQIDEKINL
                     NGGAIALGHPLGCSGARISTTLLNLMEHKDVQFGLATMCIGLGQGIATVFERV"
     gene            complement(40247..42436)
                     /gene="fadB"
                     /locus_tag="IRB70_001775"
     CDS             complement(40247..42436)
                     /gene="fadB"
                     /locus_tag="IRB70_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadB"
                     /protein_id="HBC0631696.1"
                     /translation="MLYKGDTLYLDWLEDGIAELVFDAPGSVNKLDTATVASLGEAIG
                     VLEQQSDLKGLLLRSNKAAFIVGADITEFLSLFLVPEEQLSQWLHFANSVFNRLEDLP
                     VPTIAAVNGYALGGGCECVLATDYRLATPDLRIGLPETKLGIMPGFGGSVRMPRMLGA
                     DSALEIIAAGKDVGADQALKIGLVDGVVKAEKLVEGAMAILRQAINGDLDWKAKRQPK
                     LEPLKLSKIEVTMSFTIAKGMVAQTAGKHYPAPITAVKTIEAAARFGREEALNLENKS
                     FVPLAHTNEARALVGIFLNDQYVKGKAKKLTKDVETPKQAAVLGAGIMGGGIAYQSAW
                     KGVPVVMKDINDKSLTLGMTEAAKLLNKQLERGKIDGLKLAGVISTIHPTLDYAGFDR
                     VDVVVEAVVENPKVKKAVLAETEQKVRPDTVLASNTSTIPISELANALERPENFCGMH
                     FFNPVHRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPIVVNDCPGFFVNRVLFPYFA
                     GFSQLLRDGADFRKIDKVMEKQFGWPMGPAYLLDVVGIDTAHHAQAVMTAGFPQRMQK
                     DYRDAIDALFDANRFGQKNGLGFWRYKEDSKGKPKKEEDAVVDDLLAEVSHAKRDFSE
                     EEIIARMMIPMVNEVVRCLEEGIIATPAEADMALVYGLGFPPFHGGAFRWLDTLGSAK
                     YLDMAQQYQHLGPMYEVPEGLRNKARHNEPYYPPVEPARPVGDLKTA"
     gene            42626..43957
                     /gene="pepQ"
                     /locus_tag="IRB70_001776"
     CDS             42626..43957
                     /gene="pepQ"
                     /locus_tag="IRB70_001776"
                     /EC_number="3.4.13.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro dipeptidase"
                     /protein_id="HBC0631697.1"
                     /translation="MESLASLYKNHIATLQERTRDALARFKLDALLIHSGELFNVFLD
                     DHPYPFKVNPQFKAWVPVTQVPNCWLLVDGVNKPKLWFYLPVDYWHNVEPLPNSFWTE
                     DVEVIALPKADGIGSLLPAARGNIGYIGPVPERALQLGIEASNINPKGVIDYLHYYRS
                     FKTEYELACMREAQKMAVNGHRAAEEAFRSGMSEFDINIAYLTATGHRDTDVPYSNIV
                     ALNEHAAVLHYTKLDHQAPEEMRSFLLDAGAEYNGYAADLTRTWSAKSDNDYAQLVKD
                     VNDEQLALIATMKAGVSYVDYHIQFHQRIAKLLRKHQIITDMSEEAMVENDLTGPFMP
                     HGIGHPLGLQVHDVAGFMQDDSGTHLAAPAKYPYLRCTRILQPGMVLTIEPGIYFIES
                     LLAPWREGQFSKHFNWQKIEALKPFGGIRIEDNVVIHENSVENMTRDLKLA"
     gene            43957..44571
                     /locus_tag="IRB70_001777"
     CDS             43957..44571
                     /locus_tag="IRB70_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709652.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMPACT family protein"
                     /protein_id="HBC0631698.1"
                     /translation="MESWLIPAAPVTVVEEIKKSRFITMLAHTDGVEAAKAFVESVRA
                     EHPDARHHCVAWVAGAPDDSQQLGFSDDGEPAGTAGKPMLAQLMGSGVGEITAVVVRY
                     YGGILLGTGGLVKAYGGGVNQALRQLTTQRKTPLTEYTLQCEYSQLTGIEALLGQCDG
                     KIINSDYQAFVLLRVALPAAKVAEFSAKLADFSRGSLQLLAIEE"
     gene            44610..46061
                     /gene="trkH"
                     /locus_tag="IRB70_001778"
     CDS             44610..46061
                     /gene="trkH"
                     /locus_tag="IRB70_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004146450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkH"
                     /protein_id="HBC0631699.1"
                     /translation="MHFRAITRIVGLLVILFSGTMIIPGLVALIYRDGAGRAFTQTFF
                     VALAIGSMLWWPNRKEKGELKSREGFLIVVLFWTVLGSVGALPFIFSESPNLTITDAF
                     FESFSGLTTTGATTLVGLDSLPHAILFYRQMLQWFGGMGIIVLAVAILPILGVGGMQL
                     YRAEMPGPLKDNKMRPRIAETAKTLWLIYVLLTVACALALWFAGMDAFDAIGHSFATI
                     AIGGFSTHDASIGYFDSPTINTIIAIFLLISGCNYGLHFSLLSGRSLKVYWRDPEFRM
                     FIGVQFTLVIICTLVLWFHNVYSSALMTINQAFFQVVSMATTAGFTTDSIARWPLFLP
                     VLLLCSAFIGGCAGSTGGGLKVIRILLLFKQGNRELKRLVHPNAVYSIKLGNRALPER
                     ILEAVWGFFSAYALVFIVSMLAIIATGVDDFSAFASVVATLNNLGPGLGVVADNFTSM
                     NPVAKWILIANMLFGRLEVFTLLVLFTPTFWRE"
     gene            46073..46618
                     /gene="hemG"
                     /locus_tag="IRB70_001779"
     CDS             46073..46618
                     /gene="hemG"
                     /locus_tag="IRB70_001779"
                     /EC_number="1.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="menaquinone-dependent protoporphyrinogen IX
                     dehydrogenase"
                     /protein_id="HBC0631700.1"
                     /translation="MKTLILFSTRDGQTREIASYLASELKELGIQADVANVHRIEEPQ
                     WENYDRVVIGASIRYGHYHSAFQAFVKKHATQLNSMPSAFYSVNLVARKPEKRTVQTN
                     SYARKFLMNSQWRPDRCAVIAGALRYPRYRWYDRFMIKLIMKMSGGETDTRKEVVYTD
                     WEQVANFAREIAHLTDKPTLK"
BASE COUNT        11043 a        11927 c        12477 g        11197 t
ORIGIN      
        1 tcggcatatt ttttcagaat atatttattt tttatttgga cgttctacgc tgcgtataaa
       61 tcgcatccat cacaaaaatt gccagcgcca cccaaataaa ggcgaaggtc accatcttat
      121 cggcacccgg tttttcacca taaaacgtca cagccagcag gaacatcagc gtcgggccaa
      181 tgtactgaaa aaagcctaac gttgagagac gcaggcgtgt cgcagccgca gtaaaacaca
      241 acagcggtac tgtagtgaca atcccggcgg cgatcagcag taaattcagt gacatcgggt
      301 tttgccccat atggctggtt gagctgtcgg caatagcaaa caggtaaatc gccgccacgg
      361 gcagcaacca catagtttcg attaacatgc cggtttgcgc ttcaacagca atcttcttgc
      421 gtaccaggcc gtagaaggca aaactaaacg ccagccccag cgcgataatc ggcagtgaac
      481 caaaagtcca caactgaacc aacacgccac atatcgccag aatcaccgcc agccattgca
      541 tccggcggaa tcgctcgccg aggaaaatca tccccagcac aatgttcacc agtgggttaa
      601 taaagtaacc aaggctcgct tccagcatat ggtgattgtt caccgcccag ataaacagta
      661 gccagttgcc accaatcagc acggcagaga ctgccagcat aaaaattttc tgtggcgtct
      721 gaatcagcgt ttttaaatag gaccactggc ggcaaatgct catcagcacc accataaaga
      781 aaaacgacca gatcacgcga tgcgtcagga tctcatcggc gggcacgtag taaatcagct
      841 tgaagtacgc tggcgcaata ccccaaataa aataagcggc aagagcgagt aatacgccct
      901 gccgcgtttg ttttgcatcc atcgggaata ctcattttta attggtaaca gcagtttacc
      961 tgcttttatg tcttcaacct accatatagg tggcggtggc actggcaata taaagctgtt
     1021 cttcattgtg taattcaacg cgggcgacgg cgactttatt gcctgcacgc aatagactac
     1081 tggtagcagt aaaacgctcg cccctgcctg ggcgcagata atcgacgcga agatcaatgg
     1141 tccccatccg cgatagccgc tggcgtagtt catcttcact gatggtttcg tggcgggtta
     1201 aggtacttcc cacgcacacc agaccggcgg cgacatccag cgccgacgca atgaccccgc
     1261 cgtgcaaaat gctttgcgcc cagttaccca ccatcattgg ctgattttta aaggccagct
     1321 gtgcgaactc tttttcgtaa cgctccagtt ccatccccaa tgcgcggtta aatggcatgt
     1381 gataaacaaa catctcaccc actaatttca gggcttgttc agcggtcagt acggcagaca
     1441 tatcatcctt acacttcatt ggttaatgaa atgttgattt tatgcttctt tgttgttggt
     1501 ttctacttta ggaagggata actaacggct atggagttaa gtatgtaaaa tagcccgcag
     1561 aaaaatattc accttatcaa taattcgtta cggagaacac gagcgatgcg gactctgcag
     1621 ggctggttgt tgccggtgtt tatgttgcct atggcagtat atgcacaaga ggcaacggtg
     1681 aaagaggtgc atgacgcgcc agcggtgcgt ggcagtatta tcgccaatat gctgcaggag
     1741 catgacaatc cgttcaccct ttatccttat gacaccaact acatcatcta tacccaaacc
     1801 agcgatctga ataaagaagc gattgccagt tacgactggg cggaaaatgc gcgtaaggat
     1861 gaagtaaagt ttcagttgag cctggcgttt ccgctgtggc gtgggatttt aggcccgaac
     1921 tcggtgttgg gtgcgtctta tacgcaaaaa tcctggtggc aactgtccaa tagcgaagag
     1981 tcttcaccgt ttcgtgaaac taactacgaa ccgcaattgt tcctcggttt tgccacggat
     2041 tacaactttg ctggctggac gctgcgcgat gtggaaatgg gctacaacca cgactcaaac
     2101 gggcgttcag acccgacttc ccgcagctgg aaccgccttt atacacgcct gatggcagaa
     2161 aacggtaact ggctggtaga ggtgaagccg tggtatgtgg tgggtaatac tgacgataac
     2221 ccggatatca ccaaatatat gggttactac cagcttaaaa tcggctatca cctcggtgat
     2281 gcggtgttga gtgcgaaagg acagtacaac tggaacacgg gctacggcgg cgcggagtta
     2341 ggcttaagtt acccgatcac caaacatgtg cgcctttata ctcaggttta cagcggctat
     2401 ggcgaatcgc tcatcgacta taacttcaac cagacccgcg ttggtgtggg agttatgcta
     2461 aacgacctgt tttgatgaat ggttggcaaa tctggaatcc agcatccagg attaccctct
     2521 cagagactaa aagcattgca gtttctcgcg caggcgctga aaatagcgcc tgtttttatt
     2581 tcaggcaatc ggggtgaatg tggcgcaggc ggaagtgttg aatctggagt ccggggctaa
     2641 acaggtttta caagaaacct ttggctacca acagtttcgc cccggccagg aagagattat
     2701 cgacaccgta ctttccggtc gcgattgcct ggtcgtcatg cccactggtg gcggaaaatc
     2761 cctttgctat caaattcctg ccttattgct aaacggcctt accgtggttg tttcaccgct
     2821 gatttcgttg atgaaagatc aggtggatca actgcaagcc aacggcgtgg cggcggcgtg
     2881 ccttaactcg acgcaaaccc gcgagcagca acttgacgtg atgacaggct gtcgcaccgg
     2941 gcaaatccgc ctgctgtata tcgcgccgga acgcctgatg ctggataact tccttgagca
     3001 tctggcgcac tggaatccgg tgttattagc cgttgatgaa gcgcactgta tctcccaatg
     3061 gggtcacgat ttccgcccgg aatacgctgc cctcggtcag ctgcgtcagc ggttcccgac
     3121 gctcccgttt atggcgctga ctgccacagc cgatgacacc acgcggcagg atatcgtgcg
     3181 cctgctgggg ctgaacgatc cgctgattca aatcagcagt tttgatcgcc cgaacattcg
     3241 ctacatgctg atggagaaat tcaaaccgct cgatcagttg atgcgctacg tgcaggaaca
     3301 acgcggtaag tcggggatta tttactgcaa cagccgggcg aaagtcgaag acaccgctgc
     3361 gcgcctgcaa agcaagggaa ttagcgcggc ggcctatcat gccgggctgg aaaataatat
     3421 tcgcgtcgac gtgcaggaaa aatttcagcg cgatgacctg caaattgtgg tggcgaccgt
     3481 ggcgtttggc atgggcatca acaagcctaa cgtccgcttc gtggtccact ttgatattcc
     3541 gcgcaatatc gaatcctatt atcaggaaac cggtcgcgcc gggcgtgatg gcctgcccgc
     3601 ggaagcgatg ctgttttacg atccggccga tatggcgtgg ctacgccgtt gtctggaaga
     3661 gaagccgcag gggcaattgc aggatatcga gcgccataaa ctcaatgcga tgggcgcgtt
     3721 tgccgaagcg caaacttgcc gtcgtctggt gctgctgaac tactttggcg aagggcggca
     3781 ggagccgtgc gggaactgcg atatctgcct cgatccgccg aaacaatacg atggttcaac
     3841 cgatgctcag attgcccttt ccaccattgg tcgtgtgaat cagcggtttg ggatgggtta
     3901 tgtggtggaa gtgattcgtg gcgctaataa ccagcgtatc cgcgactatg gtcatgacaa
     3961 actgaaagtc tatggcatgg gccgtgataa aagccatgaa cattgggtga gcgtgatccg
     4021 ccagctgatt cacctcggcc tggtgacgca aaatattgcc cagcattctg ccctacaact
     4081 gacagaggct gcgcgtccgg tgctgcgcgg cgaatcctct ttgcaacttg ccgtgccgcg
     4141 tatcgtggcg ctcaaaccga aagcgatgca gaaatcgttc ggcggcaact atgatcgcaa
     4201 actgttcgcc aaattacgca aactgcgtaa atcgattgcc gatgaaagca atgtcccgcc
     4261 gtacgtggta tttaacgacg caaccttgat tgagatggcg gaacagatgc cgatcactgc
     4321 cagcgaaatg ctcagcgtta acggcgttgg gatgcgcaag ctggaacgct ttggcaaacc
     4381 gtttatggcg ctgattcgtg cgcatgtcga tggcgatgac gaagagtagt cagcaggata
     4441 aaaaagtgcc aggatgaaga ctccgtaaac gtttcccccg cgagtctaat gtatgttgat
     4501 gttattcctc accgtcgcca tggtgcacat tgtggcgctt atgagccccg gtcccgattt
     4561 cttttttgtc tctcagaccg ctgtcagtcg ttcccgtaaa gaagcgatga tgggcgtgct
     4621 gggcattacc tgcggcgtaa tggtttgggc tgggattgcg ttgcttggcc tacatttgat
     4681 tatcgaaaaa atggcctggc tgcatacgct gattatggtg ggcggtggcc tgtatctctg
     4741 ctggatgggt taccagatgc tacgcggtgc actgaaaaaa gaggttgttt ctgcgcctgc
     4801 gccacaggta gaactggcaa aaagcgggcg cagtttcctg aaaggcttac tgaccaatct
     4861 cgccaatccg aaagcgatta tctactttgg ttcggtattc tcgctgtttg tcggcgataa
     4921 cgtcggcacc actgagcgct ggggcatttt cgcgttgatt attatcgaaa cactggcgtg
     4981 gtttaccgtc gttgccagcc tgtttgccct gccgcaaatg cgccgtggtt atcaacgtct
     5041 ggcgaagtgg attgatggtt ttgccggggc gttatttgcc ggatttggta ttcatttgat
     5101 tatttcgcgt taagcacttc cccctgatac gctatcaggg ggaataacat caggattgca
     5161 attgataaag gtcttcctga gaaagcccgg tcatttccat aatcaactgc aaatcaaagc
     5221 cacgctgtag cattgctttt gcgacattga gaagggcatc gcgccgaagt tcttccgcta
     5281 aagtcatcag ttcctctcct tgttgaggca ctcgttgtgc cagaccatgt actaatgttc
     5341 gtacatcctg tgcttcacct accagcgcca tgtagtttat caacatgcgt atttgctgtc
     5401 cgctcatctg ccccagaatc attaagcggg ataacttatc taacagcgtt gtcatatccc
     5461 gttgacggat atgcttctgt accagcgtaa aggcggccat gctgcggtgt tgcatgattt
     5521 cgtcatcagg aattagcgta atatcaacca gcggaaaagc atggaaatag agatcgcgtg
     5581 caatgtccgg atccggaaaa ccatcgagcc agtttgttga ccatggatat gggctacgct
     5641 ttccctggta aaaaagaatg gggatcacca gaggcagata atcatgtccc gcttcaagat
     5701 gccgctgcat ggtggcaata gcatagcgaa gcatacggaa cgccatattt tcatcaggtg
     5761 aactttgatg ctcaatcaac acatagatat atccgcaccc tttcgtcgtc tctactgaat
     5821 aaagtacgtc gttgtaatac tggcgtaggt tttcctctac aaaactgctg gactcgagat
     5881 ggagcgtatc aagattgcag agtttaacta aagaaggcgg cagatgaatt tcaataaagt
     5941 cacgggccgt ttctggtcgg gataaaaaag ccttaaagat tgcgtcatgt ggtgtcgttg
     6001 cttccgtcat ttttcatcat ccgtgggtga aatatggcgg cattctggca ctaacaaaga
     6061 gaagtaaata gtaaataaat taacagatta cgcttattac gagatgcctc gagcgcggat
     6121 gtaacaatct ctcgaggcac attaatttac gtgagcttta ttccagtttt aagcatgcct
     6181 cgccgatgct aacagcgctc ccaccagcat aaacaacgag ccgaaaatct tattcagcgc
     6241 cttcatctgc tttggtcctt taatccatag agcaatccgt tgagcaaggg tggcgtaacc
     6301 gatcatcaca ataatatcga ccacaatagt ggtgacgccg agcacgatat actgcatcag
     6361 ttgtggctgc tgcggcatga tgaattgcgg aaatagcgcc gccagaaaca caatactttt
     6421 gggattggta agattcacaa aaactgcgcg ctggaacaaa tgtcggcgcg attgagtaga
     6481 ggccagcgat ttaagatcaa ttgcgccagc ggcgcgccac tgctggatcc caagccaaat
     6541 cagataagct gcgcccgccc acttcaacac ttcaaacgca atcactgagc gggaaaatag
     6601 cgtccccaaa cccacgccaa ccagcacaat atgaatcgcc agtccggtct gaagcccagc
     6661 aatagacgcc accgcgccgc gataaccgtg gttgagcgag gtggtcatgg tgttgattgc
     6721 gccagagcct ggcgacaggc ttaaaatgat cgatgtcagc aggtaggcaa accaccattc
     6781 taaggtcatg atgaactccc ggtgtgtcta tttttgtgcc acaatacgct actgtcgcag
     6841 cgttgtgtca ggcacgctta aaaaaacgat tttacgtggt ttaagaggca gattacctga
     6901 tgtttcagca gcaaaaagac tgggaaacaa gagaaaacgc gtttgctgct tttaccatgg
     6961 gactgctgac tgatttctgg cgtcagcgtg atgaagcaga atttactggt gtggatgaca
     7021 ttccggtgcg ctttgtccgt tttcgcgcac agcaccatga ccgggtggta gtcatctgcc
     7081 cggggcgtat tgagagctac gtaaaatatg cggaactggc ctacgatctg ttccatttgg
     7141 ggtttgatgt cttaatcatc gaccatcgcg ggcagggacg ttccggtcgc ctgttagccg
     7201 atccgcatct cgggcatgtt aatcgcttta atgattatgt tgatgatctg gcggcattct
     7261 ggcaacagga ggttcagccc ggtccgtggc gtaaacgtta tatactggca cattcgatgg
     7321 gcggtgcgat ctccacatta tttctgcaac gccatccagg tgtatgtgac gccattgcgc
     7381 taactgcgcc aatgtttggg atcgtgattc gtatgccgtc atttatggca cggcagatcc
     7441 tcaactgggc cgaagcgcat ccacgtttcc gtgatggcta tgcaataggc accgggcgct
     7501 ggcgcgcgtt gccgtttgct atcaacgtac tgacccacag cagacagcga tatcgacgta
     7561 acttacgctt ctatgctgat gatccaacga ttcgcgtcgg tgggccgacc taccattggg
     7621 tacgcgaaag tattctggct ggcgaacagg tgttagccgg tgcgggtgat gacgccacgc
     7681 caacgcttct cttacaagct gaagaggaac gcgtggtgga taaccgcatg catgaccgtt
     7741 tttgtgaact ccgcaccgct gcgggccatc ctgtcgaagg aggacggccg ttggtaatta
     7801 aaggtgcgta ccatgagatc ctttttgaaa aggacgcaat gcgctcagtc gcgctccacg
     7861 ccatcgttga ttttttcaac aggcataact cacccagcgg aaaccgctct acagaggttt
     7921 aaatttctta tgtatcaggt tgttgcgtct gatttagatg gcacgttact ttctcccgac
     7981 catacgttat ccccttacgc caaagaaact ctgaagctgc tcaccgcgcg cggcatcaac
     8041 tttgtgtttg cgaccggtcg tcaccacgtt gatgtggggc aaattcgcga taatctggag
     8101 attaagtctt acatgattac ctccaatggc gcgcgcgttc acgatctgga tggcaatctg
     8161 atttttgctc ataacctgga tcgcgacatt gccagcgatc tgtttggcgt agtcaacgac
     8221 aatccggaca tcattactaa tgtttatcgc gacgacgaat ggtttatgaa tcgccatcgc
     8281 ccggaagaga tgcgcttttt taaagaagcg gtgttcaaat atgcgctgta tgagccggga
     8341 ttactggagc cggaaggcgt cagcaaagtg ttcttcacct gcgattccca tgaaaaactt
     8401 ctgccactgg agcaagcgat taacgctcgc tggggcgatc gcgtcaatgt cagtttctct
     8461 accttaacct gcctggaagt catggcgggc ggcgtgtcaa aaggccatgc gctggaagca
     8521 gtggcgaaga aactgggcta cagcctgaag gattgtattg cgtttggtga cgggatgaac
     8581 gatgccgaaa tgctgtcgat ggcggggaaa ggctgcatta tgggcagtgc gcaccagcgt
     8641 ctgaaagatc tgcatccgga actggaagtg attggtacta acgccgagga cgcagtgccg
     8701 cattatctgc gtaagctcta tttatcgtaa tcgttcttta tttggtcagt tgtcaacctg
     8761 atacttcgct acaatggata ctcgttaatc aaagagtttt ccattgtggc gctacttatc
     8821 atcaccacga ttctgtgggc cttctccttt agcttttatg gcgagtacct tgcggggcac
     8881 gtcgatagct attttgcggt tctggtgcgc gttggcctgg cggcactcgt ttttctgccg
     8941 tttctgcgta cccgtggcaa tagcctgaaa acggtcggcc tgtatatgct ggtgggcgcg
     9001 atgcagctcg gtgtgatgta tatgctgagt ttccgcgcct atctctacct gacggtctcc
     9061 gaactgttgc tgttcaccgt actgacgccg ctctacatca cgctgattta tgacatcatg
     9121 agtaagcgcc gtctgcgctg gggctatgct tttagcgcct tgctggcggt gattggtgcc
     9181 gggattattc gctatgatca ggtcaccgac catttctgga ctggcttatt gctggtgcaa
     9241 ctctccaata tcacttttgc catcggcatg gtgggttaca aacgtctgat ggaaactcgc
     9301 ccgatgccgc agcataacgc ctttgcgtgg ttctatcttg gcgcgttcct ggtggcagtg
     9361 attgcatggt tcttgctggg aaatgcacag aaaatgccgc aaaccacgtt gcaatggggc
     9421 attctggtgt ttcttggcgt ggtggcttcc gggattggct actttatgtg gaactacggc
     9481 gcgacgcagg tggacgccgg aacgctgggc attatgaata atatgcacgt tccggcaggg
     9541 ctgctggtaa acctggctat ctggcaccaa cagccgcact ggccaacgtt tattacaggc
     9601 gcgctggtga tcctggcctc actgtgggtg catcgtaagt gggtcgctcc gcgctcttca
     9661 caaacggcag atgatcgcag gcgtgattgc gcgctgaacg aataaatgct tctgtaatcg
     9721 gctgacgctg ctctccatcg cgcacggcgg cgtacagtcg gctccacaag ccttcgccca
     9781 gggttttggt caccaccaga ccctggcgct caaaactctc aactacccaa tgcggcagcg
     9841 cggcaatacc catccgcgcg gcaaccatct gaatcaacaa taaggtgtta tcgacgcttt
     9901 tcagtgacgg gctgacgcct gccggctgaa gaaaatgccg ccagacatcc agtcgactac
     9961 gctgcaccgg ataaatcaac agcgtctcgc tggcgagatc ttccggtgta attcgcgttt
    10021 tcgccgccag tggatggtca ggtgctaaca ccagacgcac ttcatagtcg aacatcggcg
    10081 aataatgcag gccactgcgc ggcagaatat cggacgtcat caccagatcc agctcgccct
    10141 gttgcaacgc aggctgcgga tcaaacgtta cgcccgattt aaaatccatc tccacctgcg
    10201 gccagttctt atggaaattt tctaatgcgg gcgtcagcca ctgaatacag ctatggcact
    10261 caatggcaat gcgcaggcgc gtctgctgcg gttcattgca ggcttgcagt gcctggctaa
    10321 tttgcggcag cacctgattt gccagttgca acaggatttc tccctgcggt gtaaagcgaa
    10381 gcggctggct tttacgcaca aatagccgga agccaaggcg ttgttccaga tcgctaaact
    10441 ggtgagacag ggcggattgc gtttgatgca acgtcgccgc agcggctgcg agtgagccgc
    10501 agttccgcaa cgcttgtagc gttttcaggt gttttacttc gatcatgaaa gtccttcact
    10561 tcggcatgaa taatttgcgc ttgaggaata tacagtaacc gccaattatg gatgtgtaaa
    10621 catctggacg gctaaatact aaaaattcca taaggggcat ataatgacaa ttcttaatca
    10681 caccctcggt ttccctcgcg ttggcctgcg tcgcgagctg aaaaaagcgc aagagagtta
    10741 ttgggcgggg aactccacgc gtgaagaact gctggcggta gggcgtgaac tgcgtgctcg
    10801 tcactgggat caacaaaagc aagcaggtat cgacctgctg ccggtgggtg attttgcctg
    10861 gtacgatcat gtcctgacca ccagcctgct gctgggtaac gttccggcgc gtcaccagaa
    10921 caaagatggt tcggtagata tcgacaccct gttccgtatt ggtcgtggac gtgcgccgac
    10981 tggcgaacct gcggcggcgg cggaaatgac caaatggttt aacaccaact atcactacat
    11041 ggtgccggag ttcgttaaag gccaacagtt caaactgacc tggacgcagc tgctggagga
    11101 agtggacgag gcgctggcgc tgggccacaa ggtgaaacct gtgctgctgg ggccggttac
    11161 ctggctgtgg ctgggtaaag tgaaaggtga acagtttgat cgcctgagcc tgctgaacga
    11221 cattctgccg gtttatcagc aagtgctggc agaactggca aaacgcggca tcgagtgggt
    11281 acagatcgac gaacccgcgc tggtactgga actaccgcag gcgtggctgg acgcctataa
    11341 acccgcttac gacgcgctcc aggggcaggt gaaactgctg ctgactactt attttgaagg
    11401 cgtaacacca aatctcgaca cgattactgc gctgcctgtt caggggctgc atgtggacct
    11461 tgtacatggt aaagatgacg ttgctgaact gcacaagcgc ctgccttctg actggctact
    11521 gtctgtgggt ctgatcaatg gtcgtaacgt ctggcgcgcc gatcttaccg agaaatatgc
    11581 gcaaattaag gacattgtcg gcaaacgtga tttgtgggtg gcatcttcct gctcactgct
    11641 gcacagcccc atcgacctga gcgtggaaac gcgtcttgat gcagaagtga aaagctggtt
    11701 tgccttcgcc ctacaaaaat gccatgaact ggcactgctg cgcgatgcgc tgaacagtgg
    11761 tgatacggcg gctctggcag agtggagcgc tccgattcag gcgcgtcgtc actctactcg
    11821 tgtacataat ccggcagtag aaaagcgtct ggcggcgatc accgctcagg acagtcagcg
    11881 tgcgaatgtc tatgaagtgc gtgctgaagc ccagcgtgcg cgttttaaac tgcccgcgtg
    11941 gccgaccacc acgattggtt ccttcccgca aactacggag attcgtaccc tgcgtctgga
    12001 ttttaaaaag ggtaatctcg acgccaataa ctaccgcacg ggcattgcgg aacatatcaa
    12061 gcaggccatt gttgagcagg aacgtttggg actggatgtg ctggtacatg gcgaggccga
    12121 gcgtaatgac atggtggaat actttggcga gcatctggat ggctttgtct ttacgcaaaa
    12181 cggttgggta cagagctacg gttcccgctg cgtgaagcca ccgattgtta ttggtgacgt
    12241 tagccgcccg gcaccgatta ctgtggagtg ggcaaaatat gcgcaatccc tgactgataa
    12301 accggtgaaa gggatgttga ccggcccggt gactattctc tgctggtcgt tcccgcgtga
    12361 agatgtcagc cgtgaaacca tcgccaaaca aattgcgctg gcgctgcgtg atgaagtggc
    12421 cgatctggaa gccgctggaa ttggcatcat ccagattgac gaaccggctc tgcgcgaagg
    12481 tttaccgctg cgtcgcagcg actgggatgt gtatctccag tggggcgtag aggccttccg
    12541 tatcaacgcc gccgtggcga aagatgacac acaaatccac actcacatgt gttattgcga
    12601 gttcaacgac atcatggatt ccattgcggc gctggacgca gacgtcatca ccatcgaaac
    12661 ctcgcgttcc gacatggagt tgctggagtc gtttgaagag tttgattatc caaatgaaat
    12721 cggtcctggc gtctatgaca ttcactcgcc aaacgtaccg agcgtggaat ggattgaagc
    12781 cttgctgaag aaagcggcaa aacgcattcc ggcagagcgt ctgtgggtca acccggactg
    12841 tggcctgaaa acgcgcggct ggccagaaac ccgcgcggca ctggcgaaca tggtgcaggc
    12901 ggcgcagaat ttgcgtcggg gatgatgagt attaacgagt cattgtaaat tgcagcacaa
    12961 taatggcttc caacaccgga agccattttg ctatgtatgc caggtatgat gtggatcttc
    13021 aggaacagaa aattaattgc ggatttctta aatattctat gcaccactga caggctttgc
    13081 ccataccatc ggaacgagcg gcaagaaata acttggtggc gtgtttatgt tcgcgcattg
    13141 gctttttaag caatttaccg ctgttcaata acggcaatgc cagatgatgt ggaatataac
    13201 caataccgac gttttgttct attaaggcga ttgccgtagc gaagtcagga acaaaaatgg
    13261 gtttttgtcc ttccaacaac caggcttgca tcggggggaa gttaacggag gtatcgcgga
    13321 tacaaaccgc tggataatga tgcaattcac tgttttctaa tggatgccgc ttcgctgcca
    13381 gtgggtggag tgggctgacg acaaaatccc attccatttg tccgaccggt tcgctaatga
    13441 tgccttcact gcttggtact gcatgaggag caccgtagac cagatcagca cgcttactgt
    13501 acagcgcatc ccagcagccg ttgtatacct caagatctac cgtcagtgtt gttgatgtga
    13561 attgccgttc aaaatctcga ataaatgcca ccagcaaatc accaggaata atattgttta
    13621 ccgctattgt cagttcacgc tcaataccat cgtgaatcag cactgtgttg cgctttaatg
    13681 cttccaggtc gccaagaata gttttgctat gttcgatgaa gtaacttccc gctggcgata
    13741 attcaatata gcgtccctta cgaatgaaca gttcaacgcc caggctctct tccgctttct
    13801 tgatggtgta actgatggcg gaagggactt tatttaactg ctcggctgcg gtggtaatgc
    13861 tctggtgtct ggcgaccaga tgaataacac gaagcgtttc gtctgagatg aacataaggc
    13921 tccctggtca gtggtaaagt ggctgaatct ctccagattc agccgtaatc attgcctgag
    13981 tatacccagg aattagcggt gttgacttgc ccgactgaga atcgcatacg cgatacatgc
    14041 caccagaatc gagtctaccg aagggatcgt cgtcagggtg aataagcctt ttacggtcat
    14101 aaagccaacc gctgcgccta tgatccatgc tgcgaatgtc agcactttaa tctgtgactc
    14161 ctgggctaac actgactctt gatagccatt acggcgataa aggaaaaagt cagcgatata
    14221 aattccggca acgggtggcg tggcgatacc caggaacagc agaaacggaa taaaccacgc
    14281 cataatatcc atactgccta cgatggcgga aaggataccc agcgccacgg taatctgcca
    14341 tttgggaaag cgggtaagca gtgtggaaac caccagcgtg ccctggaaca tattgcccgc
    14401 gttaccggtg acgcaggcga aaatcaacaa cagcgccgca ggcagaaccg caccgaatac
    14461 cgccatcgca cccagtaaag atccctgacc actaatggcg ctcggcgttg cacccgccca
    14521 gtagagcaga gggtaggcaa ccagaaacgt cacgcctgcg gcaatcagcg catgtttgcg
    14581 gttatgcaca aaactaccga aatcaggcag tgtggcaacc agcacaataa tggtgccaac
    14641 aacggtggaa acggcgacac ctgtattcat ctccacaatc gccgctggta ctgccacttc
    14701 ggtatgggtt gccacataga ggatgtaaca cagcaccagc gcgataaccg gcacggcaac
    14761 ctgggcaatt tttcccagaa cggtaaagcc aaatgccgta gaggcgacaa aaatgacaca
    14821 gccagccgcc actaacagtg ccagtggaac ttccagtcca tgttgagcca gtaagtcatg
    14881 taccgaatga ccaaacatat tggcggtaac ggcaatccag ccgaacagac ttatcgccat
    14941 caaaatgtta atggcgatgg cccctttttc gccaaacgaa tatttcacaa tgccatacgt
    15001 tggcaggcgg gctttttctc ccacgctaat ggtgatggct gaaagtaagg tcagaatgac
    15061 gccgcctaac aatacgacgc taattaaact gctgctggaa agttgattgc cgaggcttga
    15121 agatgacaac agcacaggtg tgacggcaat acccagcaaa atcatggcaa tacgcaatcc
    15181 tgatgccgta ttcagattct cttctttttt acgcatagta tgttcccttt ataaatgcgc
    15241 gttacacagt atgaaaatgc ccggtgtatt tgcgccagct acccagttct gtaatttccc
    15301 gttggccttc ggtcagccag ttttctgcca gtacgcccag cacttcgcta ccatcggcaa
    15361 gtttgatttt gccaattgcc agcccagcgg gttcgctcat taacagagcg gcaaaactgg
    15421 ccagcggtaa ttgccaaatt tctacgtcga cgtgtgttcc tccttcattc acgcgaatca
    15481 ttcccggatg gcgatcatta atactccaca accggtaatg ggcgtcagtt cggtcttcac
    15541 ggacaaaaat accgcccgct ttttgcatat ttgggttgag ttccaggccg cgcatcagcg
    15601 ttccgttaac ggctaaaagc gttgtagtca ttgtgttctc cagagaatta aagggttatc
    15661 catgtaccgc tctgatgcgc cagggctgct tttatggttt gcggtgaagt aatcaggccg
    15721 ctggcctgtt tgccttgttg ctggctggca ttgatgaaat caacaatggc ttccactttg
    15781 ggttgcatac tgccgacacc aaactgacct tcccgcaaca gcgtttgcgc ttcggcaacg
    15841 ctgatagcgt cgagccactg ttgttgtggt gtaccaaagt taatcgctac tttttctaca
    15901 ccggtgggga tcaccagcag atctgcgcct aactgactgg cgagcagcgc ggaggccaga
    15961 tctttatcga tcacggcttc cacacctttc agttgttgcc cgtctcgcac caccggaata
    16021 ccgccgccgc cgcaggcaat aaccagatat ccctggcgca ccaggtgagc gatggtgtcg
    16081 tgctcaataa tttccagtgg tgcaggagag ggaactgtac gccgccaacc acgcccggcg
    16141 tcctccatca gcgtccagcc gagttgttgt tggcgttgtt gggccgttgc ttcatcgaga
    16201 aacgcgccaa ttggtttact ggggctggcg aaagcatcgt catgtgggct gactcgcgtt
    16261 tgtgtcacca gggcaattac cggtttgttt atgccacggc gagccaattc gttatgcagc
    16321 gctttctgga acatgtagcc aattgcacct tgtgtatcac ccacggcgta atcaagtgga
    16381 accggagaaa cttcgttact ggcgagttca gagcggcgca gaataaagcc cacctgcggg
    16441 ccattaccgt gggttagtac caggtcccat ccggcttcaa ccatatcaac gatatgctgc
    16501 acgctttcca tcactgcaac atattgatcg ggaatactat tgcgttgctc gtcctgaatg
    16561 agcgcattgc cgccaaccgc gacgacagcc agtggcttaa ccatgatggt tctcctttgc
    16621 gacgatctcc gccagtgcac gtacagcggc gacaaaacag gccatcggcg cagtggtgat
    16681 cccggcacca atttgcccga cccccgcttg tttgtgggcg atacccgtat tgatgaccgg
    16741 taaaatgccg cgatcggtca ctttacgcgc atcaatccct gctgcggtgg gggcaaaatt
    16801 gagggctgga agtgtaaatg cggggttacc gccgagggtg acggcttgca tccgacggct
    16861 gttattggtg gcatcggcag gggtgcctcc cacaaatttg acgatcgccg gagacgacgc
    16921 catcgcgaag ccacccacac ctgcggtttc agtaattgcg ctatcaccca ggtcagcagc
    16981 agcgtcgtca acgccaaatc cggggaagaa cagaccttca acggcattgg caggagcctg
    17041 gaaccagcga tcgccagtac cggaaagccg aataccaaaa ttcaccccgt tacgcgccat
    17101 caccgtaacc attgaactga acggtacatt ggcggcggca tccatcattg ctttacaggc
    17161 ggccatcgac agattgagga agaagtgatc gttaccggtg ataaatgcca cgacgcgctg
    17221 gatatgttcc tgtggaagag agcaggccag caatgccggg agcaggcgct taatcagcaa
    17281 accggtagcg gcagcattgc ggttatgaac ttcatccccc atatgcagcg cctgcgccat
    17341 taatggcttg agttccagct cgccgtgttg tgcgattgct gctttcattg ccggcgccag
    17401 ttcatcgcgc atccaggcca gacgattgag aacttcatcg ttattggcgc caaaacggag
    17461 aaccttaccc agaccttcat tgaaattgct aaaagtacga tggccgttgg ttttgttttc
    17521 taccacccat aacggcatcg acgggctgat gatgcctgcc attgggccaa ccgcgtgata
    17581 atgatgacaa ggggcaaggt cgatttcgcc tgcgtttatt tggttttcag cgtcttgctg
    17641 gctggtggcc caaccttcgt acagcatggc accaataatc gcccctttta ccggaccaca
    17701 catctcttcc caggcaatcg gcgggccaga gtgcaaaata cgtttttgtt cagccattgc
    17761 tggaatggcc tctttagcga gcatgacatc caccagcacg ggctgtgctt cgagataacg
    17821 tgtcatggcg atttggttgg cattttctac caggggatga cgtagcaacg atgccagatc
    17881 caatccagcg tcaatatcgc cttgtgctgg tggctgccag ttgagtgcaa ttgcgcttcc
    17941 cccggcatgt tgaatattgt cagcaaaact gtgtagtccc gcgttcacga ccttcaaagg
    18001 ctgattaaat aaggtattca tgcgtttagc ccctttttct gcaactgagt ctgcgcaacg
    18061 gcgctggccc atagcgccgc ctgtgcattg ctgctggcaa tgatgatgcc cgcattttgt
    18121 agtgcgctta tctgctgact gcgtatttgc gaatcagctt ccgttccgca aacgtgcgca
    18181 atcagcaacg gtgcgttatt catgtcgatg tgtgaaagtt ggtccagtaa ttcgctggca
    18241 ggtgtagcgg aagcgccata accaagtacc aggtcgaata acacgacggc agtgtgtgag
    18301 tcgttgagtt cgttgagcag acgttgattg cgcagagtcg ggtcgatcat tggatgcggt
    18361 ttgccacggg tgaaatcatc gtcgcccata tcgatcaacg tgtgatcttc gctttgccag
    18421 atatttgcca gagcacgatt acccgcaact ggcgtattgg aggctgcgct gaatcccttt
    18481 tgttggcaga taagttgcgc ttcgtagcag aaggttcctc cggcgaaaac accgcgtatc
    18541 gcctggcgat gggctggcag gcgctggcag gcgttttgta acattgtgag atcgtcgcag
    18601 gaaatttcgg tctcgatagt cggaattggt tgatcattca gtaacgccac ggcgatattt
    18661 gcggcgctgg caagtgtggt ggcggcagtg atattgggac gtgccagatc atgcggattc
    18721 gcaccgagga aattcaccac cacgggtttt ccacaagcct cggcacgctc cagaatagtc
    18781 cgggcaacga tcggtgaagg cggttttgaa ataagcacaa tcacgcgagt ttcatcgtct
    18841 tgcgccagcg catctaaagc gaagagcatc gatattccac caatctcttc actgagatca
    18901 tgtccgcctg ttcccaacgc ctgagaaata cccgctccga gctggtcgat tcggcaagtc
    18961 acttcctgta gcccggtgcc tgacgcgcca ataacaccaa ttgctccgcg tttcaccaca
    19021 ttagcgaagc ctaacggaat gccgttaaca atggcggttc cacagtcagg tcccattacg
    19081 atgcgctgac gttctcgggc aagcgttttg atggattttt cctgcacgat actgacgtta
    19141 tcgctgaaca tcatcacgtt cattccgagg tttaacgctt taattgcttc ggcggcggcg
    19201 tagtctcccg gtacagaaat gagtgccagg ttggcttcgg gctcggcttc cagtgccatt
    19261 tccaggctga ccttttccgg tgatttaatg ccactatccg tttcatcatc gggtttgctg
    19321 gtcagacgtt gctgggccag taccagtgct tcattgcaaa tatcttcttc acccatgact
    19381 gcaatcacta aatcattggg actggcgttg atttcgttac ccagacccgc atcgcgcaat
    19441 tgttcgagat tattgggcgt tcccatgacg accgaggcct gttgaatacc gggcaacttg
    19501 ctgatttgcg cggaaatctg catcagagaa actgagtcct gataaagatt actgaaaact
    19561 ttatatttaa ctttcatgct gttacgcctg tttcattccg cccgatagca aaattcgggc
    19621 aaagtatccc cgtgtagccc cataaacggg ctacgggaga aaaggttgaa atcaattcat
    19681 ggtgttcagg gttcgaaagc catgcagcat tcctgcaagg caatctactc ctgacgttgc
    19741 gccaaattgc atgacctgtt ctgcacagga tgcgattgtc attgccgatg cactcccaac
    19801 cagttgtgcg agtaactggc aaatcggttc tgaaaaatgt ccctgaagcg cacgctccag
    19861 ataatgacga ctgatatccg tggtgttgtg cgcatgttga tcaattacct gctgcaaccg
    19921 gtattgatga tcggcaagtg gtgcagggag ttgccataac cagagtgctg ccagatagcc
    19981 caacaaatag tcatctccat cgggcgttaa gcctttacca aagccgatca gttgtggcac
    20041 ctggcgttcc agcgcatctg gatgctccat aatcgctaat ccctggtgcg tgagactatc
    20101 cggcaggtgc aatgtgcttt gaacgttatg ttccagacaa aataaaagcc gttgcgatgc
    20161 catcgttggg tagtgctgga aaaccaaagg gaatgcctca agtgtcagca ttccccccac
    20221 aaatggcgac tgccagagcg ttgcgttttc gagcgccaca caaaatcgag gtgtccgcag
    20281 taagcctggg gttaactgaa tgggatctga atgggcaatc tctcttcgcc agtcccaaca
    20341 ttcaggtagc cagactctgg ctgcatcagg gagattcaga tacgtttgcg cacacaacag
    20401 agtgatgaat gttcccgcgt ctgaatacag atttaccgca tgtttaaaag cgctatgtag
    20461 acgtaaatct tgcgtttcat tctgcgggaa aagatatccc aacgacgatg cgcaaagcgt
    20521 aacctgtacc atcggtgtta accttccagg cctgcaataa tggctttgga atcagtaacc
    20581 caaccgaaaa tggcaccttg tgctttgatc atctcgaggg cgtatttctg gaattccggg
    20641 aaataggagc cgacacaatc ttccgggata atgcattcat agccacgatc atttgcttcg
    20701 cgcacggtgg tggttacgca aacttcggtt gtaacaccac aaactatcag cgtcttgata
    20761 ccgtggtttt gcaaaatcag atgtaagtcg gtttgataaa acgcgccttt gccaggctta
    20821 tcaatcaccg gttcgcctgc caccgggtac agttcaggaa tgatgtcatg acctgcttca
    20881 cctctgacca gaatgcgtcc catcggtcct ggttcaccaa taaaggtttt tccgccgcgc
    20941 gtcagtttgg ctggcgggca gtcgcttaag tctgcacgat ggccttcacg agtatgaata
    21001 accataattc ctttttgacg tgcggctgcc agcacctctg tacatggtgc gatagccgtg
    21061 cgtacccgtg aaacatcatt gcccagtgcc tcaccgaagc ccccggcttc gacaaagtca
    21121 cgctgcatgt cgatcatgac cagtgcagtt gtgcgcggat caaaaggtaa ttcaaagggt
    21181 tgagcctgaa aaatggattg cgtcatggta aatctcctgt ctgatgttta aacgatccag
    21241 ttgttctgag aacgagtatt caggagaaaa gcggcacaaa acaggaaaaa agtttgccgc
    21301 acagcaacga aatttttgca ttcagcaggt ggtgtgatga cgaatgtgaa gggagtcaaa
    21361 gagtggcata cagcaacaaa ttttttgatg ctgtatggtt ttgagattaa aaaaatcgtt
    21421 gaaattgtgt gagcttaatc atcagattta gcgactatgg cgttactttt taacaccata
    21481 ctgtgtaaac cattccaaca ttcgctgcca gccgtctttc gcagactcgg catgatagct
    21541 cggacgataa tcggcgttga acgcatgccc ggcatccggg tagacgataa tctctgcttt
    21601 cgcgtttgct gcccgcagcg cctggcgcat cgtttcaacg ctctcctgcg gaatgctgtt
    21661 atcctggccg ccatataagc cgataaccgg cgcgttaaga tcggttgcga tatcaacagg
    21721 ctgtttcggt gaattcagcg tcttatcgcc ggttaatttg ccgtaccatg ccaccgctgc
    21781 tttcagttgt ggattatgcg cagcatacag ccaggtgatg cgcccacccc agcaaaatcc
    21841 ggtgatcatt aagcgatgaa catcgccgcc gttgcgtgac gcccaactgg cgacatgatc
    21901 gagatcggcc agcacctgcg agtcaggcac ttttgctacc agaccgctaa gcagcgtagg
    21961 gatatcggca aaatcattcg gatcgccttc gcggaagtaa agttcaggtg cgatagccag
    22021 atacccctcc agcgccagac ggcgacaaat atcgcggata tgttcatgca cgccaaaaat
    22081 ttcctgcact acaatgacca ctggcagtgg gccatcgctt tgctttggtc tggcatggta
    22141 agcaggcatg ttatcccctt gtgaagggat agaggtgaag cccgccacaa tcgcgtcgtc
    22201 cggagtctga acgatggtcg aagcgagagg cgatgcagca ggtgcaaatc cagattgttg
    22261 tgttgttgcc atggtattct ccgtaccctt ataaaaatgt tgcgcaatgt taactatagt
    22321 cagcatgcaa caaatcacat tgcctgaatc ggctcatctt ttatgcagtc ctgcagaatg
    22381 aagagtgatt tatgtgattt gcatcacttt tggcgggtaa atttatgcaa cgcattttcg
    22441 tcatggtgat gagtatcacg aaaaaatgtt aaacccttcg gtaaagtgtc tttttgcttc
    22501 ttctgactaa accgattcac agaggagttg tatatgtcca agtctgatgt ttttcatctc
    22561 ggcctcacta aaaacgattt acaaggggct acgcttgcca tcgtccctgg cgacccggat
    22621 cgtgtggaaa agatcgccgc gctgatggat aagccggtta agctggcatc tcatcgcgaa
    22681 ttcaccacct ggcgtgcaga gctggatggt aaacctgtta tcgtctgctc taccggtatc
    22741 ggcggcccgt ctacctctat tgctgttgaa gagctggcac agctgggcat tcgcaccttc
    22801 ctgcgtatcg gtacaacggg cgctattcag ccgcatatta atgtgggtga tgtcctggtt
    22861 accacggcgt ctgttcgtct ggacggcgcg agcctgcact tcgcaccgct ggaattcccg
    22921 gctgtcgctg atttcgaatg tacgactgcg ctggttgaag cggcgaagtc aattggtgcc
    22981 accactcacg ttggtgtgac ggcttcttct gataccttct acccgggtca ggaacgttac
    23041 gatacttact ctggtcgcgt agttcgtcac tttaaaggtt ctatggaaga gtggcaggcg
    23101 atgggcgtaa tgaactatga aatggaatct gcaaccctgc tgaccatgtg tgcaagtcag
    23161 ggcctgcgtg ccggtatggt agcgggggtt atcgttaacc gcacccagca agagatcccg
    23221 aatgctgaga cgatgaaaca aaccgaaagc catgcggtga aaatcgtggt ggaagcggcg
    23281 cgtcgtctgc tgaaataaaa aacgctcccc aacttcgggg agcgatatca gttattgacg
    23341 ccgtaaacgc attattttgc ggattattgg cgtcagtagc gtaaaggctg ccagagtcag
    23401 caatgccaga gtgatcggtc gggtatacag aaagtcgagt gacccaccag aaagcgacag
    23461 cgcacggcga aaattacttt ccgccattgg ccccataatc aatgccagca ctacgggtga
    23521 tgccggatat cctcctttct gcatgaaata gcccaccacg cctgcaatca gcataatgcc
    23581 aacatcaaaa aggctattgt tcaacgcata agtcccgacc acacaaagtg cgaggatcat
    23641 cggtgtgaga atattgccgg gaattttcac cacattaccg atgactttca aagagagcag
    23701 tccaagaact agtagcatga agtaacagaa gatcatgccg acaaacagtg tataaaccat
    23761 atcgccgtgg tcggtaaaca tcagcgggcc tggttgcatt ccctgtaacg ttaacgcgcc
    23821 cagcatgatg gcggttaccg catcgccagg gatccccagc gtcagcatag gtaacaatgc
    23881 gccaccggtg cagccattcg cgcctgcctc acaggaggcc acagctttaa tttcaccctt
    23941 accaaagttt tctggtgtct tactgaaacg acgagtttcg ttataggcaa caaaagctgc
    24001 aatatccgcc cccgcaccgg ggatcatgcc gataaaaacc cctaatcctg atgagcgcaa
    24061 aatggttaat gcaatgcggc gtagtgtttg ccagggcagt aacagactgc cgatagccac
    24121 cttcgccccc tgacgaattt gctggttttg ctccatagag cggaatgctt ctgaagcagc
    24181 aaataaacca atcatcaccg ggataaatgg cacattcatc agctccacaa atccacctgt
    24241 aaaccgtgga aaaccgccca ttggatcaag gcctatcgtt gcgatcagca atccgccaac
    24301 cccggcaatc agccctttaa tcagtgactc accggaaata ctggcaataa tgctcagtcc
    24361 gaaggttgcc agggcgaagg actccgaggc actaaatttc agcgcccaac tggcaagtac
    24421 cggagagaga aacatcagca cgataatgct gagcgttccg ccactaaagg aagagaacgt
    24481 ggcggcactc aatgccagcc ctgcttttcc ctgtttcgtc agctcataac catcaatagc
    24541 ggtggctgcg gcggcaggcg ttccgggaat tttgagcaaa attgcggtga tagaaccacc
    24601 gtagacgcca ccaaaaaaga cgccgcaaat catcaacaag ccagaaacag gctccatgcc
    24661 gtaggtgaaa ggcagcaaaa tcgccacacc catggtcgct gtcagaccag gcaaagcgcc
    24721 aatcacaata cccagcatca ccccaaaagt ggcaaacagc agcgcctgag gattattgag
    24781 taatgtcgaa aaaccctgag ttaaaagttc actttcaaac attgctggcc cctgttattc
    24841 gaaaaatgtg ccgacaggca atggcacctg taacgcttcg acaaacagca accagaggat
    24901 tgccgttaac agcagcgcaa tacccggtgt gagtacccat cgcctgtagc ccatcaacgt
    24961 cataatgacg atgaggaaaa caggagtagt aatgagataa ccgcagtagc tcatcgtcac
    25021 aatataaaac gcggttgccg caattcctgt tgccgttttc ctgaatgccg gtttttcctg
    25081 tgcgttggcg caagaggctg gttttgcctg caaaagatcg cgtatcacca gcaagacagc
    25141 gagcacaatc agggcacagg catagaaggt agggaaggca cttgcaccgg gatccgtttc
    25201 aatggcagtt gctggaaaat cagcggcatt aatcatcacc gcgccagcaa ccacacaaag
    25261 taacagcgcc accaccatcg ttgatgaaag gcgcttgcgg tgcggtacgg cgagttgagc
    25321 aacagactgt tttgtgttca tcaaccgtac ctcaggttta ttttttcagg cccaggcgag
    25381 tcagcaactc gtcaaagtac ttttcctgtt cgctgatttg ggtctggaag ctggcagcgt
    25441 caagccatgc atagttgaga ttcaactttt gcagtgcatc ctggaatgca ggctcttcag
    25501 ccgtctcttt tgctgccttt gccagaacat ccaccacatc ctgcggcgtt ttttgcgaca
    25561 caatcaggcc gcgccaggtg ccgatggaga gatcaacgcc tttctctttt aacgtcggga
    25621 cgtcaggcat ggttttcatt cgctcatccg ccatcactac cagtgtcttc agcttgccgc
    25681 ctttcacatg attgataact tcacctgggc ttacggaaac cgcttcaata tgcccgccta
    25741 acaggcctgt aatggcaggg gctgcgccgt catacgggac atgagaaaac ttcgcacccg
    25801 ttttgtcttc cagtgcagct gccgccagat gccagatagc tccggtgcct gagttaccaa
    25861 tgcgtacttt tccgggattc gctttggcgt aagtcataaa ttcgtcatag ctattccacg
    25921 gcgcatcagc acggacggtg atagccgccg gatccgcatt cagacgggcg atgggtttga
    25981 agtcgctggt tttaaaacgc accattccga ggctgggaag ggtggtcagt tcaaccgtgc
    26041 ctaaaccaat tttgtaaccg ttagggcggg cagcggcgat ttcactcagg ccgatagcgc
    26101 caccaccgcc aggtttattg ataaccccga tgctgacggg taaatggttt ttggcggcat
    26161 cagcaaaggc tcgggcaacc aggtccgtac cgcctccggc cgcgtagggt acgactaact
    26221 cgatctgttt ggttggccag gaagccgcct gtacaggtgc agtgctgagg gcagcgcctg
    26281 caagaagtac cattgcagcc atttttttcg gtaaggtaag atgttttatc attgctttta
    26341 tatccttatt tatcagttag ttgctattta aattgttcca tgcgttcata aacagtactg
    26401 cattttcata gacttgctct ggcgtcatgc cggggtgata tagcgcagaa ccgaggccaa
    26461 agccgtttgc gccgtggctc agataacgcg ccatggtttc cggtgtgata ccgccaaccg
    26521 gtaacatcgg aacggattgt ggaataaccg cacgccaggc tttggtaact tctggcgtaa
    26581 tttgttcagc cgggaacagc ttgatggcat tagcaccatg ttcaatggca gcaaaggctt
    26641 cggtgggcgt ggcgacgcca ggcgcacaat acatacccag cgcacgggcg cgacggatca
    26701 ccgcagtatc gcaatgcggc atcacgataa tctggccccc agcctcttta accgcaacca
    26761 cctgctctac cgaaagcaca gttccggctc cgaccaggca atccttaggc agggcgtcgc
    26821 gcagtaaact gatactttgc aacgcctccg gcgagttcat aggaatctca atcaggcgga
    26881 atccggcggc gtacagtttt tcaccgatgg cgacaatctc atccggtttc acgccgcgta
    26941 aaatggcgac taacccggtt ttttgcaaaa gcgtcttaaa tggcatgggt acattccctg
    27001 gcgttggtgg acagtaaccc ggcagcgtgg gcgattcgcc ataatccctg ttcagtggca
    27061 ttaggaatgg cgtgtatctg tctgtcggga aaaacgtggc tgaatgcttg tgaatagcgg
    27121 ctgttcagat ttgcgctacc gattaaggcg atcggtgttg tggcgggtaa atcacgtagc
    27181 aaactggatg ccagaccaca taattcatgg cctatcagta atccggaaag gtaatccccc
    27241 tgcgaggacg acgtaagatt actggtcagc aggcgcgaac gggtcgaaaa cagcgtcgat
    27301 aataatccgg tctgatgatg ctcttgtgct gctgtcagcc cgtgggtgaa ggcatcccag
    27361 tgcggttcat ctccaggatg catggtggca ccgagaatcg aatggcggga taaaacatca
    27421 aataactcgc ccgtcataaa ggttcggaaa tcggtaatgg tgttgttttc aactactgcc
    27481 catttcgcat gtgtgccggg taagcctatc agcactggca taccctgatg gatcgcgttt
    27541 tgcagggccg gttccatcga gatagcaccg aagatttgtg tctcttcgcc acgcatcact
    27601 tcgggcattt caccttcttt aatcacgcca ggaatgatgt gcagcattgt ctgctgctgg
    27661 tggataacag gcgtcaactg cttcgccaga ccctcgagag tgaccgggca aggtaaataa
    27721 gctgctggtt gccacccttg cgcactgccg agcatgccgc aagccagtac cgggcatggg
    27781 gtttgtgcca gccagtcgcc gcagacacgt aaaaacgtat cgtggaaagc gtcctcacgt
    27841 gttgctgcct gggagggtaa tttcatgatc ccccagggga attcacgttt ttcttgtgga
    27901 tttggtgatt cgccaaaacg ccatgcccga agcgatgacg ttccccagtc cagggcaata
    27961 aatgagggtg ctcccggcat tagtcgtttc ctttaatcat ggtttattta tctttgcgga
    28021 cgtgcttacc ccagcccagt tcagcggata tctcttctgc acaggatttg acgtaaggtg
    28081 ccagttcttc cagacgcgcc agcgacatat acgtggtggt actggcgaca gaaatagccg
    28141 ccacaatttc atcccgggcg ttgtaaaccg gcgctgcaac gcaacggata gtcggctcgt
    28201 tctcttccag atcaaaagca aaaccactgg cggcataacg acgcatgttc tgaataaatg
    28261 cgcccagttt tgtttcatca ccacaggtct taaacagcgt gcgccactct tcttctgttc
    28321 ggttgaggat caatgccttg ccgatgccgg tgattgccag tggcatgcga tggcctgggc
    28381 gtgagcgcat ttccagcccg cgctgactgt tgatcttctc cagatacagc acttcgtcgc
    28441 cttcaacgat ccccagatgc acggtgtcca gggtgtaacg ggcaaggcgt tgcaaaacgg
    28501 gctgggcaat ttcgtacagc gaggtgcttt ccagtgctct ggcaccgaat tcgatcagtt
    28561 tggcacccag ttggtagccc tgcgttggga catggcgcag gtaacgttgt tccaccagaa
    28621 cggtgactaa acgatgggtt gtgctccggg tcgtgccggt gaactcgccg atacttttta
    28681 ggtcatggca gccgttataa acagcattaa gaaccgccag tccacgtaat aacgtttgtg
    28741 cgcctgcggt ggttgaagag gtttctgcca tacgtttctc ctgatgatat tgctgaagtg
    28801 ttccacataa tgacgtgggg aaaaggtgat atatcccaca atataaactc catctcatat
    28861 tgtgggataa aataatgaaa attaacgatc gttttgcgta gcgcctcgca ggaaacttct
    28921 ttcaaactgg acgtttgtac agcacaattc tattttgtgc gggtaagttg ttgcgtcagg
    28981 aggcgttgtg gatttctcaa tcatggttta cgcagttatt gcattggtgg gtgtggcaat
    29041 tggctggctg tttgccagtt atcaacatgc gcagcaaaaa gccgagcaat tagctgaacg
    29101 tgaagagatg gtcgcggagt taagcgcggc aaaacaacaa attactcaaa gcgagcactg
    29161 gcgcgctgag tgcgagttac tcaataacga agtgcgcagc ctgcaaagta ttaacacctc
    29221 tctggaggcc gatctgcgtg aagtaaccac gcggatggaa gctgcacagc aacatgctga
    29281 cgataaaatt cgccagatga ttaacagcga gcagcgcctc agtgagcagt ttgaaaacct
    29341 cgccaaccgt atttttgagc acagcaatcg ccgggttgat gagcaaaacc gtcagagcct
    29401 gaacagcctg ttgtcgccgc tacgtgaaca actggacggt ttccgccgtc aggtccagga
    29461 cagctttggt aaagaagccc aagaacgtca taccctgact cacgaaatcc gcaacctcca
    29521 gcaactcaac gcccagatgg cccaggaagc gatcaacctg acgcgtgcgc tgaaaggcga
    29581 caataaaacc cagggcaact ggggcgaggt agtattgacg cgggtgctgg aggcttccgg
    29641 tctgcgtgaa gggtatgaat atgaaaccca ggtcagcatc gaaaatgacg cccgctcgcg
    29701 gatgcagccg gatgtcatcg tgcggttgcc gcagggaaaa gatgtggtga tcgacgccaa
    29761 aatgacgctg gtcgcctatg aacgctattt caacgctgaa gatgactaca cacgtgaaag
    29821 cgcgctacag gagcatatcg cgtcggtgcg taaccacatc cgcttgcttg gacgcaaaga
    29881 ttatcaacag ttgccggggc tgcgaaccct ggattacgtg ctgatgttta tccccgttga
    29941 gccagcattt ttattggcac tggatcgcca gccggagctg atcaccgaag cgttgaaaaa
    30001 caatatcatg ctggttagcc cgactacgct gctggtggcg ctgcgcacta tcgccaacct
    30061 gtggcgttat gagcatcaaa gccgcaacgc ccagcaaatc gccgatcgtg ccagcaagct
    30121 gtacgacaag atgcgtttgt tcatcgatga catgtccgcg attggtcaaa gtctcgacaa
    30181 agcgcaggat aactatcgcc aggcaatgaa aaaactctct tcaggtcgcg gaaatgtgct
    30241 ggcgcaggca gaagcgtttc gcggtttagg ggtagaaatt aaacgcgaga ttaatccgga
    30301 tttggctgaa caggcggtga gccaggatga agagtatcga cttcggtcgg ttccggagca
    30361 accgaatgat gaagcttatc aacgcgatga tgaatataat cagcagtcgc gctagcccat
    30421 tgggggtagt taagccgggt agaaatctag ggcatcgacg cccaatctgt tacacttctg
    30481 gaacaatttt ttgatgagca ggcattgaga tggtggataa gtcacaagaa acgacgcact
    30541 ttggttttca gaccgtcgcg aaggaacaaa aagcggatat ggtcgcccac gttttccatt
    30601 ccgtggcatc aaaatacgat gtcatgaatg atttgatgtc attcggtatt catcgtttgt
    30661 ggaagcgatt cacgattgat tgcagcggcg tacgccgtgg gcagaccgtg ctggatctgg
    30721 ctggtggcac cggcgacctg acagcgaaat tctcccgcct ggtcggagaa actggcaaag
    30781 tggtccttgc tgatatcaat gaatccatgc tcaaaatggg acgcgagaag ctgcgtaata
    30841 tcggtgtgat tggcaacgtt gagtatgttc aagcgaacgc tgaggcgctg ccgttcccgg
    30901 ataacacctt tgattgcatc accatttcgt ttggtctgcg taacgtcacc gacaaagata
    30961 aagcactgcg ttcaatgtat cgcgtgctga aacccggcgg ccgcctgctg gtgcttgagt
    31021 tctcgaagcc aattatcgag ccgctgagca aagcctatga tgcatactcc ttccatgtgc
    31081 tgccgcgtat tggctcactg gtcgcgaacg acgccgacag ctaccgttat ctggcagaat
    31141 ccatccgtat gcatcccgat caggataccc tgaaagccat gatgcaggat gccggattcg
    31201 aaagtgtcga ctactacaat ctgacggcag gggttgtggc gttgcatcgt ggttataagt
    31261 tctgacagga gaccggaaat gccttttaaa cctttagtga cggcaggaat tgaaagtctg
    31321 ctcaacacct tcctgtatcg ctcacccgcg ctgaaaacgg cccgctcgcg tctgttgggc
    31381 aaagtgctgc gcgtggaggt aaaaggcttt tcgacgtcat taattctggt gttcagcgaa
    31441 cgccaggttg atgtactggg cgaatgggca ggcgatgctg actgcaccgt tatcgcctac
    31501 gccagtgtgt tgccgaaact tcgcgatcgc cagcagcttg ccgcactgat tcgcagtggt
    31561 gagctggaag tgcagggcga tattcaggtg gtgcaaaact tcgttgcgct ggcagatctg
    31621 gcagagttcg accctgcgga actgctggcc ccttataccg gtgatatcgc cgctgaagga
    31681 atcagcaaag ccatgcgcgg aggcgcaaag ttcctgcatc acggcattaa gcgccagcaa
    31741 cgttatgtgg cggaagccat tactgaagag tggcgtatgg cacccggtcc gcttgaagtg
    31801 gcctggtttg cggaagagac ggctgccgtc gagcgtgctg ttgatgccct gaccaaacgg
    31861 ctggaaaaac tggaggctaa atgacgccag gtgaagtacg gcgcctatat ttcatcattc
    31921 gcactttttt aagctacgga cttgatgaac tgatccccaa aatgcgtatc accctgccgc
    31981 tacggctatg gcgatactca ttattctgga tgccaaatcg gcataaagac aaacctttag
    32041 gtgagcgact acgactggcc ctgcaagaac tgggaccggt atggatcaag ttcgggcaga
    32101 tgttatcaac ccgccgtgat ctttttccgc cgcatattgc cgatcagctg gcgttattgc
    32161 aggacaaagt cgctccgttt gatggcaagc tggcgaagca gcagattgaa gctgcaatgg
    32221 gcggattgcc ggtagaagcg tggtttgatg attttgaaat caagccgctg gcttctgctt
    32281 ctatcgccca ggttcatacc gcgcgattga aatcgaatgg taaggaggtg gtgattaaag
    32341 ttatccgccc ggatattttg ccggttatta aagcggatct gaaacttatc taccggctgg
    32401 ctcgctgggt gccgcgtttg ctgccggatg gtcgccgtct gcgcccaacc gaagtggtgc
    32461 gcgagtacga aaagaccttg attgatgaac tgaatttgct gagggaatct gccaacgcca
    32521 ttcagcttcg gcgcaatttt gaagacagcc cgatgctcta catcccggaa gtttaccctg
    32581 actattgtag tgaagggatg atggtgatgg agcgcattta cggcattccg gtgtctgatg
    32641 ttgcggcgct ggagaaaaac ggcactaaca tgaaattgct ggcggaacgc ggcgtgcagg
    32701 tgttcttcac tcaggtcttt cgcgacagct ttttccatgc cgatatgcac cctggcaaca
    32761 tcttcgtaag ctatgaacac ccggaaaacc cgaaatatat cggcattgat tgcgggattg
    32821 ttggctcgct aaacaaagaa gataaacgct atctggcaga aaactttatc gccttcttta
    32881 atcgcgacta tcgcaaagtg gcagagctac acgtcgattc tggttgggtg ccaccagata
    32941 ccaacgttga agagttcgaa tttgccattc gtacggtctg tgaacctatc tttgagaaac
    33001 cgctggccga aatttcgttt ggacatgtac tgttaaatct gtttaatacg gcgcgtcgct
    33061 tcaatatgga agtgcagccg caactggtgt tactccagaa aaccctgctc tacgtcgaag
    33121 gggtaggacg ccagctttat ccgcagctcg atttatggaa aacggcgaag cctttcctgg
    33181 agtcgtggat taaagatcag gtcggtattc ctgcgctggt gagagcattt aaagaaaaag
    33241 cgccgttctg ggtcgaaaaa atgccagaac tgcctgaact ggtttacgac agtttgcgcc
    33301 agggcaagta tttacagcac agtgttgata agattgcccg cgagcttcag tcaaatcatg
    33361 tacgtcaggg acaatcgcgt tattttctcg gaattggcgc tacgttagta ttaagtggca
    33421 cattcttgtt ggtcagccga cctgaatggg ggctgatgcc cggctggtta atggcaggtg
    33481 gtctgatcgc ctggtttgtc ggttggcgca aaacacgctg attttttcat cgctcaaggc
    33541 gggccgtgta acgtataatg cggccttgtt taatcatcat ctaccacaga ggaacatgta
    33601 tgggtggtat cagtatttgg cagttattga ttattgccgt catcgttgta ctgctttttg
    33661 gcaccaaaaa gctcggctcc atcggttccg atcttggtgc gtcgatcaaa ggctttaaaa
    33721 aagcaatgag cgatgatgaa ccaaagcagg ataaaaccag tcaggatgct gattttactg
    33781 cgaaaactat cgccgataag caggcggata cgaatcagga acaggctaaa acagaagacg
    33841 cgaagcgcca cgataaagag caggtgtaat ccgtgtttga tatcggtttt agcgaactgc
    33901 tattggtatt catcatcggc ctcgtcgttc tggggccgca acgactgcct gtggcggtaa
    33961 aaacggtcgc gggctggatt cgcgcgttgc gttcactggc gacaacggtg cagaacgaac
    34021 tgacccagga gttaaaactc caggagtttc aggacagtct gaaaaaggtt gaaaaggcga
    34081 gcctcactaa cctgacaccc gaactgaaag cgtcgatgga tgaattacgc caggccgcgg
    34141 agtcgatgaa gcgttcctac gttgcaaacg atcctgaaaa ggcgagcgat gaagcgcaca
    34201 ccatccataa cccggtggtg aaagacaatg aagctgcgca tgaaggcgta acgcctgccg
    34261 ctgcacaaac gcaggccagt tcgccggaac agaagccaga aaccacgcca gagccggtgg
    34321 taaaacctgc tgcggacgct gaaccgaaaa ccgctgcacc ttccccttcg tcgagtgata
    34381 aaccgtaaac atgtctgtag aagatactca accgcttatc acgcatctga ttgagctgcg
    34441 taagcgtctg ctgaactgca ttatcgcggt gatcgtgata ttcctgtgtc tggtctattt
    34501 cgccaatgac atctatcacc tggtatccgc gccattgatc aagcagttgc cgcaaggttc
    34561 aacgatgatc gccaccgacg tggcctcgcc gttctttacg ccgatcaagc tgacctttat
    34621 ggtgtcgctg attctgtcag cgccggtgat tctctatcag gtgtgggcgt ttatcgcccc
    34681 agcgctgtat aagcatgaac gtcgcctggt ggtgccgctg ctggtttcca gctctctgtt
    34741 gttttatatc ggcatggcgt tcgcctactt tgtggtcttt ccgctggcat ttggcttcct
    34801 tgccaatacc gcgccggaag gggtacaggt atccaccgac atcgccagct atttaagctt
    34861 cgttatggcg ctgtttatgg cgtttggtgt ctcctttgaa gtgcctgtgg caattgtgct
    34921 gctgtgctgg atggggatta cctcgccaga agacttacgc aaaaaacgcc cgtatgtgct
    34981 ggttggtgca ttcgttgtcg ggatgttgct gacgccgccg gatgtcttct cgcaaacgct
    35041 gctggcgatc ccgatgtact gcctgtttga aatcggtgtc ttcttctctc gcttttacgt
    35101 tggtaagggt cgaaaccggg aagaggaaaa cgacgctgaa gcagaaagcg aaaaaactga
    35161 agaataaatt caaccgcccg tcagggcggt tgtcatatgg agtacaggat gtttgatatc
    35221 ggcgttaatt tgaccagttc gcaatttgcg aaagaccgtg atgatgttgt agcgcgcgct
    35281 tttgacgcgg gagttaatgg gctactcatc accggcacta acctgcgtga aagccagcag
    35341 gcgcaaaagc tggcgcgtca gtattcgtcc tgttggtcaa cggcgggcgt acatcctcac
    35401 gacagcagcc agtggcaagc tgcgactgaa gaagcgatta ttgagctggc cgcgcagcca
    35461 gaagtggtgg cgattggtga atgtggcctc gactttaacc gcaacttttc gacgccggaa
    35521 gagcaggaac gcgcttttgt tgcccagcta cgcattgccg cagaattaaa catgccggta
    35581 tttatgcact gtcgcgatgc ccacgagcgg tttatgacat tgctggagcc gtggctggat
    35641 aaactgcctg gtgcggttct tcattgcttt accggcacac gcgaagagat gcaggcgtgc
    35701 gtggcgcgtg gaatttatat cggcattacc ggttgggttt gcgatgaacg acgcggactg
    35761 gagctgcggg aactgttgcc gttgattccg gcggagaaat tgctgatcga aactgatgcg
    35821 ccgtatttgc tcccgcgcga tctcacgccg aaaccatcat cccggcggaa cgagccagcc
    35881 catctgcccc atattttgca acgtattgcg cactggcgtg gagaagatgc cgcatggctg
    35941 gctgccacca cggatgccaa tgttaaaaca ctgtttggga ttgcgtttta gagtttgcgg
    36001 aactcggtgt tcttcacact gtgcttaatc tctttattga taagattaag taacagcatg
    36061 gagcgagcct cgccgtcggg ttcggtgaaa atggcctgaa aaccttcgaa cgcgccttcg
    36121 gtaataatca ccttatcacc cggataaggg gttgccggat cgacaatgtc tttcggttta
    36181 tataccgata gctgatgaat caccgccgat gggactatcg ctggcgacgc gccaaagcgc
    36241 acgaagtggc tgacaccgcg ggtcgcgttg atagtcgtgg tatgaatcac ttccggatcg
    36301 aactccacaa acaagtagtt ggggaacaat ggctcactga ctgcagtacg tttgccacgc
    36361 acgatttttt ccagggtgat catcggtgcc aggcaattca cagcctgtct ttcgaggtgt
    36421 tcctgggcac gttgaagttg cccgcgcttg cagtacagta aataccagga ttgcataatg
    36481 actcttatcc gtttaatcgg ggcgcaagga tagcaaaagc tttacgctaa gttaattata
    36541 ttccccggta tgcgttatac cgtcagagtt cacgctaatt taacaaattt acagcatcgc
    36601 aaagatgaac gccgtataat gggcgcagat taagaggcta caatggacgc catgaaatat
    36661 aacgatttac gcgacttctt gacgctgctt gaacagcagg gtgagctaaa acgtatcacg
    36721 ctcccggtgg atccgcacct ggaaatcact gaaattgctg accgcacttt gcgtgccggt
    36781 gggcctgcgc tgttgttcga aaaccctaaa ggctactcaa tgccggtgct gtgcaacctg
    36841 ttcggtacgc caaagcgcgt ggcgatgggc atggggcagg aagatgtttc ggcgctgcgt
    36901 gaagttggta aattattggc gtttctgaaa gagccggagc cgccaaaagg tttccgcgac
    36961 ctgtttgata aactgccgca gtttaagcaa gtattgaata tgccgacaaa gcgactgcgt
    37021 ggtgcgccct gccaacaaaa aatcgtctct ggcgatgacg tcgatctcaa tcgcattccc
    37081 attatgacct gttggccgga agatgccgcg ccgctgatta cctgggggct gaccgtaacg
    37141 cgcggtccgc ataaagagcg tcagaatctg ggcatttatc gccagcagct gattggtaaa
    37201 aacaaactga ttatgcgctg gctgtcgcat cgcggtggcg cgctggatta tcaggagtgg
    37261 tgtgcggcgc atccgggcga acgtttcccg gtttctgtgg cgctgggtgc cgatcccgcc
    37321 acgattctcg gcgcagtcac ccccgttccg gatacgcttt cagagtatgc gtttgccgga
    37381 ttgctgcgcg gcaccaagac cgaagtggtg aagtgtatct ccaatgacct ggaagtgccc
    37441 gccagtgcgg agattgtgct ggaagggtat atcgaacaag gcgaaactgc gccggaaggg
    37501 ccgtatggcg accacaccgg ttactataac gaagtcgata gtttcccggt attcaccgtg
    37561 acgcatatta cccagcgtga agatgcgatt taccattcca cctataccgg gcgtccgccg
    37621 gatgaacctg cggtgctggg tgtcgcactg aacgaagtgt ttgtgccgat tctgcaaaaa
    37681 cagttcccgg aaattgtcga tttttacctg ccgccggaag gatgttctta tcgtctggcg
    37741 gtagtgacga tcaaaaaaca gtacgccgga cacgcgaagc gcgtcatgat gggcgtctgg
    37801 tcgtttttac gccagtttat gtacactaag tttgtgatcg tttgcgatga tgacgtcaac
    37861 gcacgcgact ggaacgatgt gatttgggcg attaccaccc gtatggaccc ggcgcgggac
    37921 acggtgttgg tcgaaaatac gcctattgat tatctggatt ttgcctcgcc tgtgtccggg
    37981 ctgggttcaa aaatggggct ggatgccacg aataaatggc cgggggaaac ccagcgtgaa
    38041 tggggacgtc ccatcaaaaa agatccagat gttgtcgcgc atattgacgc catctgggat
    38101 gaactggcta tttttaacaa cggtaaaagc gcctgatgcg cgtttgtttt gccctattta
    38161 tcgatccgac agagaaagcg catgacaacc ttaagctgta aagtgacctc ggtagaagct
    38221 atcacggata ccgtataccg tgtccgaatc gtaccagacg cggccttttc ttttcgtgct
    38281 ggtcagtatt tgatggtagt gatggatgag cgtgacaaac gtccgttctc aatggcttcg
    38341 acgccggatg aaaaaggttt catcgagctg catattggcg cttctgaaat caacctttac
    38401 gcgaaagcag tcatggaccg cattcttaaa gatcatcaaa tcgtggtcga tattccgcac
    38461 ggtgaggcat ggctgcgcga tgatgaagaa cgtccgatga ttttgattgc gggtggcacc
    38521 gggttctctt atgcgcgctc gattttgctg acggcgctgg cgcgtaaccc aaaccgtgat
    38581 atcaccattt actggggcgg gcgtgaagag cagcatcttt atgatctctc cgagcttgag
    38641 gcgctttcgt tgaagcatcc tggtctacaa gtggtgccgg tggttgaaca accggaagcg
    38701 ggctggcgtg ggcgtactgg caccgtgtta acggcggtat tgcaggatca tggtacgctg
    38761 gcagagcatg atatctatat tgccggacgt tttgagatgg cgaaaattgc ccgtgacctg
    38821 ttttgcagcg agcgtaatgc gcgggaagat cgcctgtttg gcgatgcgtt tgcatttatc
    38881 tgagatataa aaaacccgcc cctgacaggc gggaagaacg gcaactaaaa ctttatacag
    38941 tggcatttag atctatgtcg catccggcaa tcggtgcacg atgcctgatg cgacgctggc
    39001 gcttcttatc agacccacat gggtgcagga tcggtagacc ggataaggcg ttcacgccgc
    39061 atccggcaag tggttaaacc cgctcaaaca ccgttgcaat gccctgaccc agaccgatac
    39121 acatcgtcgc cagaccaaac tggacgtctt tgtgttccat cagattcagc agcgtggtgc
    39181 tgatacgcgc accggaacaa cccagcggat gacccagcgc gatcgcgcca ccgttgaggt
    39241 tgatcttctc gtcaatctgc tccattagcc cgagatcttt aatacacggc aggatctgcg
    39301 cggcaaaggc ttcgttcatc tcgaatacgc cgatatcgct ggcagaaagc cccgcttttt
    39361 tcagcgccag cttcgaggcc ggaaccgggc cgtaacccat aatcgatggg tcacaaccaa
    39421 cgaccgccat cgaacgcacg cgggcgcgcg gcttaagacc taattctcgg gcgcggcttt
    39481 cactcatcac cagcatggca gctgcgccat cggaaagcgc agaagatgta cctgccgtca
    39541 ccgtaccgct gacgggatca aacgccgggc gcagcgtggc gagggcttcc acggtggttt
    39601 ccgggcgaat cacttcgtcg taattaaact gcttcaggac gccgtcggca tcgtgaccac
    39661 cggtcgggat aatttcattt ttaaatgcac ccgactgcgt ggcggcccag gcgcgggcgt
    39721 gtgaccgcgc ggcaaaggca tcctgcattt cacggctgat accgtgcata cgcgccagca
    39781 tttctgccgt taagcccatc atgcccgccg ctttggcgac attgcggctc aggccggggt
    39841 gaaaatcgac gccgtgactc atcggcacat ggcccatatg ctccacgccg ccaaccagac
    39901 atgcctgcgc atcgccggtc atgatcattc gcgctgcgtc atgtaatgct tgcatggatg
    39961 aaccacacag gcgattgacg gtcaccgccg ggacagagtg tggtacttct gccaacagcg
    40021 ccgcgttacg ggcgatatta aaaccttgct ccagcgtctg ctgtacacag ccccagtaaa
    40081 tatcgtcgag ggcagccgct tccagcgccg ggttacgcgc cagcaggcta cgcattaaat
    40141 gagcggagag atcttctgca cgcacgtgac gaaaagcacc gcccttcgaa cggcccatcg
    40201 gggtgcgaat tgcatcgaca atgacaacct gttccattgt gactccttaa gccgttttca
    40261 ggtcgccaac cggacgggct ggctcaaccg ggggatagta cggttcgtta tgacgcgctt
    40321 tattacgcag accttccggc acttcataca tcgggccgag gtgctgatat tgttgtgcca
    40381 tatcgaggta ttttgcgcta ccgagggtgt ccagccagcg gaacgcgccg ccgtggaacg
    40441 gagggaaccc cagtccgtag accagcgcca tatccgcttc tgctggagtg gcgataatgc
    40501 cttcttccag acagcgcacc acttcgttga ccatcgggat catcatgcgg gcgataatct
    40561 cttcttcgct gaaatcgcgc ttcgcgtggc tgacctctgc cagcaggtcg tcaacgacgg
    40621 cgtcttcttc tttcttcggc ttgcctttac tgtcttcttt ataacgccag aaaccgaggc
    40681 cgttcttctg accaaaacgg ttggcatcaa acagcgcatc gatggcatcg cggtaatctt
    40741 tctgcatccg ctgcgggaag cctgctgtca tcaccgcctg agcgtgatgc gcggtatcaa
    40801 tccccacaac gtccagcaga tatgccggcc ccatcggcca gccaaactgt ttttccatca
    40861 ctttgtcgat cttgcggaaa tccgcgccgt cgcgcagcag ctggctgaaa cccgcgaagt
    40921 aggggaacag cacgcggtta acgaagaatc cggggcagtc gttaaccaca atcggcgtct
    40981 tgcccatctt gctcgcccat gcgacgactt tcgcgatggt ttcgtcggag cttttctcgc
    41041 cgcgaataat ttccaccaac ggcatccggt gcaccgggtt aaagaagtgc atcccgcaga
    41101 agttttccgg acgttccagc gcgttggcca gttcgctgat aggaatggtt gaagtgttag
    41161 acgccagcac ggtatccggg cgtactttct gctcggtttc tgccagcacg gcttttttca
    41221 ctttcgggtt ttcaacaacc gcttctacca caacatccac gcggtcaaac ccggcgtagt
    41281 cgagcgttgg gtgaattgtg gagatcacgc cagccagttt cagaccatcg atcttgccgc
    41341 gctcaagctg cttgttcagc agtttcgcgg cttcggtcat gccgagggtt aacgacttgt
    41401 cgttgatatc tttcatgaca accggcacgc ctttccacgc agactggtaa gcgatgccgc
    41461 cgcccataat gcctgcgccc agcacagcgg cctgtttcgg ggtttcaaca tctttggtga
    41521 gtttcttcgc tttacctttt acatattgat cgttaaggaa aatgccgacc agtgcgcggg
    41581 cttcgttggt atgcgccagc gggacaaaac ttttgttttc caggtttaag gcttcttcac
    41641 gaccaaaacg ggccgcagct tcaatggttt ttactgcggt gatgggggcc ggataatgtt
    41701 tccccgccgt ttgcgcgacc atccctttag cgatggtgaa gctcatggtg acttcaatct
    41761 tgctcagttt tagcggttcc agcttcggct gacgttttgc tttccagtcg aggtcgccgt
    41821 taatggcctg gcgtaaaatc gccatcgccc cttcaaccag tttttctgct ttgactacgc
    41881 catccaccag accgattttc agcgcctgat ccgcgccgac atctttaccg gcggcaatga
    41941 tttccagcgc actgtcagcg cccagcatac gtggcatacg tacagaaccg ccaaagcccg
    42001 gcatgatgcc cagtttagtt tccggcagac cgatgcgcag atccggcgtc gccagacgat
    42061 aatcggtcgc cagcacgcat tcgcagccac cgcccagcgc atagccgttg acagcagcaa
    42121 tggtcggcac cggcagatcc tccaggcgat taaacacgct attggcaaag tgtagccact
    42181 gacttaactg ttcttcagga acgaggaaca gggacaaaaa ttcggtgata tcagcaccga
    42241 cgataaaggc tgctttgttc gaacgcagca gcagcccttt tagatctgat tgctgttcca
    42301 gcacgccgat ggcctcgccg aggctggcga cggtggcagt gtcgagttta ttaactgaac
    42361 ctggggcatc aaataccagt tcggcaatgc catcttccag ccagtcaagg tacagggtgt
    42421 cgcctttgta aagcatgtca gtctcctgaa tccgcaaggt gatctggtcg taccagatga
    42481 atcgaagtgt gtattttgtg ttaaaaatat gcaaacaaaa gattaaagaa atgccgatct
    42541 gatcacgctc ggcagaaatc acgctctgga tgaacgatgt gctaagatgc ggagacttaa
    42601 ggtcaaaaaa acagaagggt aaaaaatgga atcactggcc tcactctata aaaatcatat
    42661 agctacctta caagaacgga ctcgcgatgc gctggcgcgc ttcaagctgg atgcgttact
    42721 tattcactcc ggcgaactgt tcaacgtttt tctcgacgat catccctatc cgtttaaagt
    42781 gaacccgcaa ttcaaagcgt gggtgccggt aactcaggtg ccaaactgct ggttgctggt
    42841 ggatggcgtg aacaagccga aactgtggtt ttatctgccg gttgattact ggcacaacgt
    42901 cgaaccgctg ccgaactcct tctggactga agatgtggaa gtgatcgcgc tgccgaaagc
    42961 cgatggcatt ggtagcctgc tgcctgctgc gcgcggcaat atcggttata tcggtccggt
    43021 gccggaacgt gcgctgcaac tgggtattga ggccagcaac atcaacccga aaggggtgat
    43081 cgactacctg cattactacc gctccttcaa aaccgagtac gaactggcct gtatgcgtga
    43141 agcgcagaaa atggcggtca acggtcatcg tgcggcagaa gaagcgttcc gttctggcat
    43201 gagcgagttc gatatcaata ttgcctatct gaccgcgacc ggtcatcgtg atactgacgt
    43261 accttacagc aacattgtgg cgcttaacga acacgctgcg gtgttgcatt acaccaaact
    43321 ggaccaccag gcaccggaag agatgcgcag cttcctgctg gatgccgggg ccgaatataa
    43381 cggctatgcg gctgacctga cccgtacctg gtcggcaaaa agcgacaacg actacgcaca
    43441 gctggtgaaa gacgtaaatg atgaacaact ggcgctgatc gccaccatga aagcaggcgt
    43501 cagctatgtg gattatcaca tccagttcca tcagcgcatc gccaaactgc tgcgtaaaca
    43561 tcaaatcatc accgatatga gtgaagaagc gatggtcgaa aacgatctca ccggaccttt
    43621 tatgccgcac ggtatcggtc atccgctggg cctgcaggtg catgacgtag ctggctttat
    43681 gcaagatgat agcggtacgc acctcgcggc accggcaaaa tatccgtacc tgcgctgcac
    43741 ccgtattctc cagccgggca tggtgttaac catcgaaccg ggtatctact tcatcgaatc
    43801 gctgctggca ccgtggcgtg aagggcagtt cagcaagcac ttcaactggc agaaaattga
    43861 agcactgaaa ccgttcggcg gcattcgtat cgaagacaat gtggtgatcc acgaaaacag
    43921 cgtggaaaac atgacccggg atctgaaact ggcgtgatgg aaagctggtt aattcctgcg
    43981 gcaccggtca cggtcgttga agagatcaaa aaaagccgct tcataacgat gttggcgcat
    44041 accgatggcg ttgaggcggc gaaagcgttt gttgaatcgg tacgggcaga acaccccgat
    44101 gcccgccacc attgcgtagc gtgggtggcg ggtgcgccgg atgattctca acagctcggt
    44161 ttctctgacg acggggaacc ggcgggaacg gccggtaaac cgatgctcgc ccaactaatg
    44221 ggcagcggcg tcggggaaat taccgctgtg gtggtgcgct actacggcgg catattgctt
    44281 ggtaccggtg ggttagtgaa agcgtatggc ggcggcgtga atcaggcgct gcgccagcta
    44341 acgacccaac gcaagacgcc attaaccgaa tatactttgc aatgtgaata tagtcagtta
    44401 accggcattg aagcgttgct ggggcagtgt gacggcaaaa ttatcaacag tgattatcag
    44461 gcattcgttc tgctgcgggt ggcgcttccg gcggcgaaag tggctgaatt ttccgcaaag
    44521 ctggcggatt ttagccgtgg ttcattgcaa ttgttagcga ttgaagaata atccccactt
    44581 cgttttgcag aactaaggaa gcggcagaga tgcattttcg cgccattacc cgaatcgttg
    44641 gactactggt catcttattt tcagggacca tgattatccc tgggctggta gcactcatct
    44701 accgggatgg agcgggccgc gcttttaccc agaccttttt tgtcgccctc gccattggct
    44761 ctatgctgtg gtggccgaac cgcaaagaga agggcgaact gaaatcccgt gaggggtttc
    44821 tgatagtggt gctgttctgg accgtgctgg gtagcgtcgg tgcgctccct tttatcttct
    44881 cggaaagccc gaacctcacg attaccgatg cgttttttga atctttctct ggcctgacca
    44941 ccacgggagc cactacgctg gtggggctgg attcgctccc tcatgccatc ctcttttatc
    45001 gccagatgct gcaatggttt ggcgggatgg ggatcatcgt gctggcggtt gcgatactgc
    45061 ctatcctcgg cgtgggtggg atgcagctct atcgcgcaga aatgcccggc ccgctgaaag
    45121 ataacaaaat gcgcccgcga attgcggaaa cggcgaaaac cctgtggttg atttatgtct
    45181 tgctgaccgt cgcctgtgcg ctggcgttgt ggtttgccgg aatggatgcc tttgatgcca
    45241 tcggccatag ctttgcgact atcgctattg gcggcttctc gacacatgat gccagtatcg
    45301 gttatttcga cagcccgact attaacacta tcattgctat cttcctgctg atctccggct
    45361 gtaactacgg tctgcacttt tcactgttaa gtgggcgtag tctgaaggtt tattggcgcg
    45421 atccggaatt tcgcatgttt atcggcgtac agtttacgct ggtgattatt tgtaccctcg
    45481 tgctgtggtt tcataatgtc tatagttcgg cgctgatgac aattaaccag gcgtttttcc
    45541 aggtggtgtc gatggcgaca accgccgggt ttacgactga cagcattgcc cgctggccgc
    45601 tctttttgcc ggtactgctc ttatgttcag cttttatcgg cggttgtgcc gggtcaacgg
    45661 gcggtggcct gaaagtgatc cgcatcctgc tgctgtttaa gcaggggaac cgtgagctga
    45721 aacgactggt gcatccgaac gccgtctaca gcattaagct ggggaatcgc gcactgccgg
    45781 aacgtatcct cgaagccgtt tggggatttt tctccgccta tgcattggtg tttattgtca
    45841 gtatgctggc gattatcgcc acgggcgtgg atgacttttc tgcctttgcc tcggttgttg
    45901 cgacattgaa taacctgggg ccagggcttg gtgtggttgc tgataacttt accagtatga
    45961 acccggtggc taaatggatc ctgattgcca acatgctgtt tggtcgtctt gaggtcttta
    46021 cattgctggt gctctttacc ccgactttct ggcgtgaatg atggagtaat acgtgaaaac
    46081 attaattctt ttctcaacaa gggacggaca aacgcgcgag attgcctcct acctggcttc
    46141 ggaactgaaa gaactgggta tccaggcgga tgttgctaat gtacaccgca ttgaagaacc
    46201 acagtgggaa aactacgacc gtgtggtcat tggagcttct attcgctacg gtcattacca
    46261 ttcagcgttc caggcatttg tcaaaaagca tgccacccag ctgaactcaa tgccgagcgc
    46321 cttttactct gtcaacctgg tggcacgcaa gccggagaag cggactgtgc agaccaacag
    46381 ctacgcccga aagtttctga tgaactcaca atggcgcccc gatcgctgtg ccgtcattgc
    46441 cggggcgctg cgttatccac gctatcgttg gtacgaccgt tttatgatca agctgattat
    46501 gaagatgtca ggcggtgaaa cggatacgcg caaagaagtt gtctataccg attgggagca
    46561 ggtggcgaat ttcgcccgag aaatcgccca tttaaccgac aaaccgacgc tgaaataagc
    46621 ataaagaata aaaaatgcgc ggtc
//
LOCUS       DADXDL010000026        46177 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.026, whole genome shotgun sequence.
ACCESSION   DADXDL010000026 DADXDL010000000
VERSION     DADXDL010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 46177)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46177)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46177
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.026"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            724..900
                     /locus_tag="IRB70_001780"
     CDS             724..900
                     /locus_tag="IRB70_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016158417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631701.1"
                     /translation="MKKTFTFSLLAIVFASLLSACVPHHHHRHSDGPRGPAPSDKAMP
                     PSNGGPNHGSHGGY"
     gene            complement(937..2856)
                     /gene="dhaR"
                     /locus_tag="IRB70_001781"
     CDS             complement(937..2856)
                     /gene="dhaR"
                     /locus_tag="IRB70_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001467850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase operon
                     transcriptional regulator DhaR"
                     /protein_id="HBC0631702.1"
                     /translation="MSGAFNNDGRDISPLIATSWERCNKLMKRETWNVPHQAQGVTFA
                     SIYRRKKAMLTLGQAALEDAWEYMAPRACALLILDETACILSRNGDPQTLQQLSTLGF
                     NDGTYCAEGIIGTCALSLAAISGQAVKTMADQHFKQALWNWAFCATPLFDSKGRLTGT
                     IALACPVEQTTAADLPLTLAIAREVGNLLLTDSLLAETNRHLNQLNALLESMDDGVIS
                     WDEQGNLQFINAQAARVLRLDATASQGRAITELLTLPAVLQQAIKQAHPLKHVEATFE
                     SQHQFIDAVITLKPIIETQGTSFILLLHPVEQMRQLMTSQLGRVNHTFAHMPQDDPQT
                     RRLIHFGRQAARSSFPVLLCGEEGVGKALLSQAIHNESERAAGPYIAVNCELYGDAAL
                     AEEFIGGDRTDNENGRLSRLELAHGGTLFLEKIEYLAVELQSALLQVIKQGVITRLDA
                     RRLIPIDVKVIATTTADLAMLVEQNRFSRQLYYALHAFEITIPPLRMRRGSIPALVNN
                     KLRSLEKRISTRLKIDDDALARLVSCAWPGNDFELYSVIENLALSSDNGRIRVSDLPE
                     HLFTEQATDDVSATRLSTSLSFAEVEKEAIINAAQVTGGRIQEMSALLGIGRTTLWRK
                     MKQHGIDAGQFKRRG"
     gene            3084..4154
                     /gene="dhaK"
                     /locus_tag="IRB70_001782"
     CDS             3084..4154
                     /gene="dhaK"
                     /locus_tag="IRB70_001782"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309732.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBC0631703.1"
                     /translation="MKKLINDVQDVLDEQLAGLAKAHPSLILHQDPVYVTRADAPVAG
                     KVALLSGGGSGHEPMHCGYIGQGMLSGACPGEIFTSPTPDKIFECAMQIDGGEGVLLI
                     IKNYTGDILNFETATELLHDSGVKVTTVVIDDDVAVKDSLYTAGRRGVANTVLIEKLV
                     GAAAERGDSLDACAELGRKLNNQGHSIGIALGACTVPAAGKPSFTLADNEMEFGVGIH
                     GEPGIDRRPFSSLDQTVDEMFDTLLENGSYHRTLRFWDYQQGSWQEEPQTKQPLQSGD
                     RVIALVNNLGATPLSELYGVYSRLTTRCQQAGLTIERNLIGAYCTSLDMTGFSITLLK
                     VDDETLALWDAPVHTPALNWGK"
     gene            4165..4797
                     /gene="dhaL"
                     /locus_tag="IRB70_001783"
     CDS             4165..4797
                     /gene="dhaL"
                     /locus_tag="IRB70_001783"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase ADP-binding subunit
                     DhaL"
                     /protein_id="HBC0631704.1"
                     /translation="MSLSRTQIVNWLTRCGDIFSTESEYLTGLDREIGDADHGLNMNR
                     GFSKVVEKLPAIADKDIGFILKNTGMTLLSSVGGASGPLFGTFFIRAAQTTQARQSLT
                     LEELYQMFRDGADGVISRGKAEPGDKTMCDVWVPVVESLRQSCEQNLPVPAALDAASS
                     IAESAAQSTITMQARKGRASYLGERSIGHQDPGATSVMFMMQMLALAAKE"
     gene            4808..6226
                     /gene="dhaM"
                     /locus_tag="IRB70_001784"
     CDS             4808..6226
                     /gene="dhaM"
                     /locus_tag="IRB70_001784"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415716.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaM"
                     /protein_id="HBC0631705.1"
                     /translation="MVNLVIVSHSSRLGEGVGELARQMLMSDNCKIAIAAGIDDPQNP
                     IGTDAVKVMEAIESVADADHVLVMMDMGSALLSAETALELLAPEIAAKVRLCAAPLVE
                     GTLAATVSAASGADIDKVIFDAMHALEAKREQLGLPSSDTEISDTCPPYDEEARSLSV
                     VIKNRNGLHVRPASRLVYTLSTFNADMLLEKNGKCVTPESINQIALLQVRYNDTLRLI
                     AKGPEAEEALIAFRQLAEDNFGETEEVAPPTLRPVPPVSGKAFYYQPVLCTVQAKSIL
                     TVEEEQERLRQAIDFTLLDLMTLTAKAETSGLDDIAAIFSGHHTLLDDPELQAAASEL
                     LQHEHCTAEYAWQHVLKELSQQYQQLDDEYLQARYIDVDDLLHRTLVHLTQTKEELPQ
                     FNSPTILLAENIYPSTVLQLDPAVVKGICLSAGSPLSHSALIARELGIGWICQQGEKL
                     YAIQPEETLTLDVKTQRFNRQG"
     gene            6546..8243
                     /gene="treA"
                     /locus_tag="IRB70_001785"
     CDS             6546..8243
                     /gene="treA"
                     /locus_tag="IRB70_001785"
                     /EC_number="3.2.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HBC0631706.1"
                     /translation="MKSPTPSRPQKMALIPACIFLCFAALSVQAEETSVTPQPPDILL
                     GPLFNDVQNAKLFPDQKTFADAVPNSDPLMILADYRMQQNQSGFDLRHFVNVNFTLPK
                     EGEKYVPPEGQSLREHIDGLWPVLTRSTENTEKWDSLLPLPEPYVVPGGRFREVYYWD
                     SYFTMLGLAESGHWDKVADMVANFAHEIDTYGHIPNGNRSYYLSRSQPPFFALMVELL
                     TQHEGDAALKQYLPQMQKEYAYWMDGVENLQAGQQEKRIVKLQDGTLLNRYWDDRDTP
                     RPESWVEDIATAKSNPNRPATEIYRDLRSAAASGWDFSSRWMDNPQQLNTLRTTSIVP
                     VDLNSLMFKMEKILARASKAAGDNAMANQYETLANARQKGIEKYLWNDQQGWYADYDL
                     KSHKVRNQLTAAALFPLYVNAAAKDRASKMATATKTHLLQPGGLNTTSVKSGQQWDAP
                     NGWAPLQWVATEGLQNYGQKEVAMDISWHFLTNVQHTYDREKKLVEKYDVSATGTGGG
                     GGEYPLQDGFGWTNGVTLKMLDLICPKEQPCDNVPATRPLSESTTQPLKQKEAEPTP"
     gene            8573..9595
                     /locus_tag="IRB70_001786"
     CDS             8573..9595
                     /locus_tag="IRB70_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707101.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter substrate-binding protein"
                     /protein_id="HBC0631707.1"
                     /translation="MSLTRRRFTQILASTLFLHHLPSFAQSVKFWASLTLPEAQNITR
                     IVSAGAPADLLLLAVAPEKMVGFSSFDFARQALIPLPEHIRQFPRLGRLAGRASTLSL
                     EGLMALHPDLVVDCGNTDETWISQARQVSEQTQIPWLLLNGKLEQSAEQLTTLGKTLG
                     EEHRATEQANLASRFVGEAQAFATSPAANLSFYAARGPRGLETGLQGSLHTEAAELLG
                     LHNVAQIADRHGLTQVSMENLLRWQPDIILVQEAVTADFIRRDPLWQGVKAVAEQRIL
                     FLSGLPFGWLDAPPGINRLLGLRRLHAWLDPAINRQFKSDMQHYAQLFWHCSLSDADY
                     QKLVAN"
     gene            9595..10575
                     /locus_tag="IRB70_001787"
     CDS             9595..10575
                     /locus_tag="IRB70_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBC0631708.1"
                     /translation="MRTVNGCILLLAAISITFAAVSGAYHLDMQQLLALILRQENVPV
                     QEQIVFWQIRVPRILAALFLGAALAGAGTTYQGMFRNPLVSPDILGVSAGAGLGACAA
                     ILWGLSIVYIQLYAFCGGLMVVAGVWLITRRVTRHDPILTLVLVGIALGTLCGAGISL
                     IKTLADPYTQLPSITFWLLGGLSTVTLRDLCYAAPIILIGSLPLFFLRWRMNLLTLSD
                     DEARSLGLNVTRLRFGLIVCATLITASTVAIAGIIGWVGLVVPHIARLLTGHNHQQLL
                     PMAMCTGAILLLLTDTLARSIGTTEIPLGILTAFVGAPFFLFLLLRGGRQ"
     gene            10572..11330
                     /locus_tag="IRB70_001788"
     CDS             10572..11330
                     /locus_tag="IRB70_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0631709.1"
                     /translation="MTLLAVRHASLGYSRHPVLRDVSFTLSQGTICCLLGANGCGKTT
                     LMRSILGVIPLLKGEILLDSLPVQTLSHRQRAQAIAWVPQAHDGIFAFSVLDMVLMGL
                     APTIGAFSVPGKQERLKATEQLEKLGILHLATRRWNTLSGGERQLALIARALVQQPRL
                     LLLDEPASSLDFGHQIQLLDTLAQLKNNGMTMLMSTHHPLHANAIADSIIQVEPDGRV
                     TQGLPTEQLTTKKLAALYRVSADQIHHHLSAIKH"
     gene            11340..12152
                     /locus_tag="IRB70_001789"
     CDS             11340..12152
                     /locus_tag="IRB70_001789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000903984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBC0631710.1"
                     /translation="MLIDDIDFADLYLQQLRLAHRTEKTPDHWDQRAEKMAENCASPT
                     DSYLQQLTAKIDLQGAQTLFDMGCGPGTVSLALADKLTTIYGVDYSQGMLNVAARRAA
                     ALKADNVHWIQRAWEEDWSDLPRCDIAVASRSTLVADMRQAMSKLNNQARLRVYTTHL
                     VSTSFVSPAIQRAAGREVIELPNYIFALNVLYQMGIYAHVDFIRGQNCQQDNSTWERF
                     EQNVSWSIGALNDDERERLYHWYQQQDARALAPASRDWALIWWDSVPQEALR"
     gene            12149..13003
                     /locus_tag="IRB70_001790"
     CDS             12149..13003
                     /locus_tag="IRB70_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ModD protein"
                     /protein_id="HBC0631711.1"
                     /translation="MIFLSQAQIDALLLEDIQGGDLTTRALNIGHQHGYIEFFHRQGG
                     CVSGISVACKMLTTLGLTIDDAVSDGSQANAGQRLIRAQGNAAALHQGWKAVQNVLEW
                     SCGVSDYLAQMLALLRERYPDGNIACTRKAIPGTRLLASQAILAAGGLIHRAGCAETI
                     LLFANHRHFLHDNQDWSGAINQLRRHAPEKKIVVEADTPKEAIAALRAQPDVLQLDKF
                     NPQQATEIAQIAPSLAPHCTLALTGGINLTTLKNYLDCGIRLFITSAPYYATPADIKV
                     SLQPAASI"
     gene            13029..14999
                     /locus_tag="IRB70_001791"
     CDS             13029..14999
                     /locus_tag="IRB70_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HBC0631712.1"
                     /translation="MRLKKRYLCTALSLAFTQQAVAAQESDTLTVWSSPVSSTTTTVL
                     DQPTMKALDKQNVAQALSVVPGVVLQKSGSRNEEQVKVRGFDSRQVPVYFDGVPIYVP
                     YDGNLDLARILTNNLGAVEVSKGYSSLLQGPNQMGGAINITTQKPTKPLEASLGYRQG
                     WSRSQDNAYDMHASFAASSDLGYLQVSGSQLKQDFLGLPHGVNNDIAGKHGKMINSSA
                     DDKRGIVKLGFTPRENDEYTLTYIKQDGEKDNPPYSGNSGQKSRYWQWPEYDKESFYY
                     QGTTQLNDRFTLKSRLYRDTFENTLMMYNSLADLKNKKGSYSHYSDYSDGAGLQLAAD
                     VRENDLLSFAVNWKDDVHREKGAPHAAYDRYEDRTWSLASEYQWAAADNVDVVAGISY
                     DWRDSVEAKKHEKDGSITHYDDNNQSAFNWQVMGKYHFANEDTLALSYYDRTRFPTLK
                     ERYTTSKPAYNQIAIVNPQLKPERARGVDLTWNGAFTHDWGFEVSVYYNRVSDAILSH
                     NIDADTIQNQNSGTVDYSGLDAGIKGKISNILDVGLSYALIHADAKRKDIGKITDLPT
                     QTMTAWMTLKPWEPLSVTLSEEARSSSYSNSDGSQKAAGFAVTHIRADYTLGHGFSVN
                     ASVNNLFDTKYAYSEGFIEEGRNFWAGIEYTF"
     gene            complement(15049..15303)
                     /locus_tag="IRB70_001792"
     CDS             complement(15049..15303)
                     /locus_tag="IRB70_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBC0631713.1"
                     /translation="MGIIAWIIFGLIAGIIAKLIMPGRDGGGFFLTCILGIVGAVVGG
                     WLATMFGIGGTISGFNLHSFLVAVVGAILVLGVFRLLRRE"
     gene            15504..16238
                     /locus_tag="IRB70_001793"
     CDS             15504..16238
                     /locus_tag="IRB70_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar brake protein"
                     /protein_id="HBC0631714.1"
                     /translation="MSHYHEQFLKQNPLAVLGVLRDLHKAAIPLRISWNGGQLISKIL
                     AITPDKLVLDFGSQAEDNIAVLKAQHITITAETQGAKVEFTVEQLQQSEYLQLPAFIT
                     VPPPTLWFVQRRRYFRISAPLHPPYFCQTKLADNSTLRFRLYDLSLGGMGALLETAKP
                     AGLHEGMRFAQIEVNMGQWGVFHFDAQLISISERKVIDGKNETITTPRLSFRFLNVSP
                     TVERQLQRIIFSLEREARKKADKVRD"
     gene            complement(16240..16851)
                     /gene="emtA"
                     /locus_tag="IRB70_001794"
     CDS             complement(16240..16851)
                     /gene="emtA"
                     /locus_tag="IRB70_001794"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309714.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     EmtA"
                     /protein_id="HBC0631715.1"
                     /translation="MKFRWFAFLIVLLAGCSSKHDYTNPPWNAKVPVQRAMQWMPISQ
                     KAGAAWGVDPQLITAIIAIESGGNPNAVSKSNAIGLMQIKASTSGRDVYRRMGWSGEP
                     TTSELKNPERNISMGAAYLNILETGPLAGIEDPKVLQYALVVSYANGAGALLRTFSSD
                     RKKAISKINDLDADEFLDHVARNHPAPQAPRYIYKLEQALDAM"
     gene            16951..17865
                     /gene="ldcA"
                     /locus_tag="IRB70_001795"
     CDS             16951..17865
                     /gene="ldcA"
                     /locus_tag="IRB70_001795"
                     /EC_number="3.4.17.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="muramoyltetrapeptide carboxypeptidase"
                     /protein_id="HBC0631716.1"
                     /translation="MSLFHLIAPSGYCIKQHAALRGIQRLTDAGHQVNNVEVIARRCE
                     RFAGTETERLEDLNSLARLTTPNTIVLAVRGGYGASRLLADIDWQALVARQQHDPLLI
                     CGHSDFTAIQCGLLAHGNVITFSGPMLVANFGADELNAFTEHHFWLALRNETFTIEWQ
                     GEGPTCQTEGTLWGGNLAMLISLIGTPWMPQIENGILVLEDINEHPFRVERMLLQLYH
                     AGILPRQKAIILGSFSGSTPNDYDAGYNLESVYAFLRSRLSIPLITGLDFGHEQRTVT
                     LPLGAQAMLNNTQEGTQLTISGHPVLKM"
     gene            17960..19696
                     /locus_tag="IRB70_001796"
     CDS             17960..19696
                     /locus_tag="IRB70_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium/proton antiporter"
                     /protein_id="HBC0631717.1"
                     /translation="MDATTIISLFILGSILVTSSILLSSFSSRLGIPILVIFLAIGML
                     AGVDGVGGIPFDNYPFAYMVSNLALAIILLDGGMRTQASSFRVALGPALSLATLGVLI
                     TSGLTGMMAAWLFNLDLIEGLLIGAIVGSTDAAAVFSLLGGKGLNERVGSTLEIESGS
                     NDPMAVFLTITLIAMIQQHESSVSWMFVVDILQQFGLGIVIGLGGGYLLLQMINRIAL
                     PAGLYPLLALSGGILIFALTTALEGSGILAVYLCGFLLGNRPIRNRYGILQNFDGLAW
                     LAQIAMFLVLGLLVNPSDLLPIAIPALILSAWMIFFARPLSVFAGLLPFRGFNLRERV
                     FISWVGLRGAVPIILAVFPMMAGLENARLFFNVAFFVVLVSLLLQGTSLSWAAKKAKV
                     VVPPVGRPVSRVGLDIHPENPWEQFVYQLSADKWCVGAALRDLHMPKETRIAALFRDN
                     QLLHPTGSTRLREGDVLCVIGRERDLPALGKLFSQSPPVALDQRFFGDFILEASAKYA
                     DVALIYGLEDGREYRDKQQTLGEIVQQLLGAAPVVGDQVEFAGMIWTVAEKEDNEVLK
                     IGVRVAEEEAES"
     gene            19816..19977
                     /locus_tag="IRB70_001797"
     CDS             19816..19977
                     /locus_tag="IRB70_001797"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631718.1"
                     /translation="MDDKPLQALANELKTPAQESQRNGFFRLQQVKKNQPRITGIPVN
                     HQGPLPDIA"
     gene            20316..21752
                     /locus_tag="IRB70_001798"
     CDS             20316..21752
                     /locus_tag="IRB70_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631719.1"
                     /translation="MASFKDICPFAPAIPPSSVNPGVRRPPGRLFLSAELKNQILQNM
                     KYLSPQKFSWGDAPWQIIDLSTAGKVNIQVDNNTIITLGTPLNQQHNEFMMVAKWCEW
                     AIQQDGLQENLQKKLHEVLEENRQNKQSEIPQEDLKERLKEIKEDILKENQSASQIED
                     RAEALRRMKECLITRQSMLDLSNLGLTSLPENLPPHLIEFNCSRNMLTALPEVMPKGL
                     RVLECMENFLILLPKVQPPKLMVLKCYENYIIWLPELSTNLRVIDCSENFLQFLPPSM
                     PQYLYTLRCAFNSISLIPDEMLENLTRLKVFDCSSNDLISSPRLPPKLIIYYCGENQF
                     KTVPVPQPRSLKVFSCNGNPWDKDNLPTLLKAVEGLKNQEGLEELLDFLHKEGLVDLE
                     GLEELEDLDDLMDLEFLDDPELLERVKVQEDLELLDQQLGLLSLEKQQDSQPVNQQSE
                     HEPESASRVKRDLSEVEFESTMKRKRFM"
     gene            complement(21920..22990)
                     /gene="dadX"
                     /locus_tag="IRB70_001799"
     CDS             complement(21920..22990)
                     /gene="dadX"
                     /locus_tag="IRB70_001799"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309712.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolic alanine racemase DadX"
                     /protein_id="HBC0631720.1"
                     /translation="MTRPIQASLDLQALKQNLSIVRQAAPHARVWSVVKANAYGHGIE
                     RIWSALGATDGFALLNLEEAITLRERGWKGPILMLEGFFHAQDLEIYDQYRLTTCVHS
                     NWQLKALQNARLKAPLDIYLKVNSGMNRLGFQPDRVLTVWQQLRAMANVGEMTLMSHF
                     AEAEHPDGISSAMARIEQAAEGLECRRSLSNSAATLWHPEAHFDWVRPGIILYGASPS
                     GQWRDIANTGLRPVMTLSSEIIGVQTLKAGERVGYGGRYTARDEQRIGIVAAGYADGY
                     PRHAPTGTPVLVDGVRTMTVGTVSMDMLAVDLTPCPQAGIGTPVELWGKEIKIDDVAA
                     AAGTVGYELMCALALRVPVVTV"
     gene            complement(23000..24298)
                     /gene="dadA"
                     /locus_tag="IRB70_001800"
     CDS             complement(23000..24298)
                     /gene="dadA"
                     /locus_tag="IRB70_001800"
                     /EC_number="1.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-amino acid dehydrogenase"
                     /protein_id="HBC0631721.1"
                     /translation="MRVVILGSGVVGVASAWYLNQAGHEVTVIDREPGAALETSAANA
                     GQISPGYAAPWAAPGVPLKAIKWMFQRHAPLAVRLDGTQFQLKWMWQMLRNCDTSHYM
                     ENKGRMVRLAEYSRDCLKALRAETNIQYEGRQGGTLQLFRTEQQYENATRDIAVLEDA
                     GVPYQLLESSRLAEVEPALAEVAHKLTGGLQLPNDETGDCQLFTQNLARMAEQAGVKF
                     RFNTPVDQLLCDGEQIYGVKCGDEVIKADAYVMAFGSYSTAMLKGIVDIPVYPLKGYS
                     LTIPIAQEDGAPVSTILDETYKIAITRFDNRIRVGGMAEIVGFNTELLQPRRETLEMV
                     VRDLYPRGGHVEQATFWTGLRPMTPDGTPVVGRTRFKNLWLNTGHGTLGWTMACGSGQ
                     LLSDLLSGRTPAIPYEDLSVARYSRGFTPSRPGHLHGAHS"
     gene            24628..26160
                     /locus_tag="IRB70_001801"
     CDS             24628..26160
                     /locus_tag="IRB70_001801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpoVR family protein"
                     /protein_id="HBC0631722.1"
                     /translation="MATIDSMNKDTTRLSDGPDWTFDLLDVYLAEIDRVAKLYRLDTY
                     PHQIEVITSEQMMDAYSSVGMPINYPHWSFGKKFIETERLYKHGQQGLAYEIVINSNP
                     CIAYLMEENTITMQALVMAHACYGHNSFFKNNYLFRSWTDASSIVDYLIFARKYITEC
                     EERYGVDEVERLLDSCHALMNYGVDRYKRPQKISLQEEKARQKSREEYLQSQVNMLWR
                     TLPKREEEKTVAEARRYPSEPQENLLYFMEKNAPLLESWQREILRIVRKVSQYFYPQK
                     QTQVMNEGWATFWHYTILNHLYDEGKVTERFMLEFLHSHTNVVFQPPYNSPWYSGINP
                     YALGFAMFQDIKRICQSPTEEDKYWFPDIAGSDWLDTLHFAMRDFKDESFISQFLSPK
                     VMRDFRFFTVLDDDRHNYLEISAIHNEEGYREIRNRLSSQYNLSNLEPNIQIWNVDLR
                     GDRSLTLRYIPHNRAPLDRGRKEVLKHVHRLWGFDVMLEQQNEDGSVELLERCPPRMG
                     NL"
     gene            complement(26212..26931)
                     /gene="fadR"
                     /locus_tag="IRB70_001802"
     CDS             complement(26212..26931)
                     /gene="fadR"
                     /locus_tag="IRB70_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid metabolism transcriptional regulator
                     FadR"
                     /protein_id="HBC0631723.1"
                     /translation="MVIKAQSPAGFAEEYIIESIWNNRFPPGTILPAERELSELIGVT
                     RTTLREVLQRLARDGWLTIQHGKPTKVNNFWETSGLNILETLARLDHESVPQLIDNLL
                     SVRTNISTIFIRTAFRQHPDKAQEVLATANEVADHADAFAELDYNIFRGLAFASGNPI
                     YGLILNGMKGLYTRIGRHYFANPEARSLALGFYHKLSALCSEGAHDQVYETVRRYGHE
                     SGEIWHRMQKNLPGDLAIQGR"
     gene            27154..28695
                     /gene="nhaB"
                     /locus_tag="IRB70_001803"
     CDS             27154..28695
                     /gene="nhaB"
                     /locus_tag="IRB70_001803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)/H(+) antiporter NhaB"
                     /protein_id="HBC0631724.1"
                     /translation="MEISWGRALWRNFLGQSPDWYKLALIIFLILNPLIFIISPFVAG
                     WLLVAEFIFTLAMALKCYPLLPGGLLAIEAVFIGMTSAEHVREEVAANLEVLLLLMFM
                     VAGIYFMKQLLLFIFTRLLLSIRSKMLLSLSFCMAAAFLSAFLDALTVVAVVISVAVG
                     FYGIYHRVASSRTEDTDLQDDSHIDKHYKVVLEQFRGFLRSLMMHAGVGTALGGVMTM
                     VGEPQNLIIAKAAGWHFGDFFLRMSPVTVPVLICGLLTCLLVEKLRCFGYGETLPEKV
                     REVLQQFDDQSRHQRTRQDKIRLIVQAIIGVWLVTALALHLAEVGLIGLSVIILATSL
                     TGVTDEHAIGKAFTESLPFTALLTVFFSVVAVIIDQQLFSPIIHFVLQASEHAQLSLF
                     YIFNGLLSSISDNVFVGTIYINEAKAAMESGAITLKQYELLAVAINTGTNLPSVATPN
                     GQAAFLFLLTSALAPLIRLSYGRMVWMALPYTLVLTLVGLLCVEFTLAPVTEWFMQMG
                     WIATL"
     gene            28841..29371
                     /gene="dsbB"
                     /locus_tag="IRB70_001804"
     CDS             28841..29371
                     /gene="dsbB"
                     /locus_tag="IRB70_001804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="disulfide bond formation protein DsbB"
                     /protein_id="HBC0631725.1"
                     /translation="MLRFLNQCSQGRGAWLLMAFTALALELTALWFQHVMLLKPCVLC
                     IYERCALFGVLGAALIGAIAPKTPLRYVAMVIWLYSAFRGVQLTYEHTMLQLYPSPFA
                     TCDFMVRFPEWLPLDKWVPQVFVASGDCAERQWDFLGLEMPQWLLGIFIAYLIVAVLV
                     VISQPFKAKKRDLFGR"
     gene            complement(29417..30685)
                     /gene="umuC"
                     /locus_tag="IRB70_001805"
     CDS             complement(29417..30685)
                     /gene="umuC"
                     /locus_tag="IRB70_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V catalytic protein"
                     /protein_id="HBC0631726.1"
                     /translation="MFALCDVNAFYASCETVFRPDLWGKPVVVLSNNDGCVIARNAEA
                     KALGVKMGDPWFKQKDLFRRCGVVCFSSNYELYADMSNRVMSTLEELSPRVEIYSIDE
                     AFCDLTGVRNCRDLTDFGREIRATVLQRTHLTVGVGIAQTKTLAKLANHAAKKWQRQT
                     GGVVDLSNLERQRKLMSALPVDEVWGIGRRISKKLDAMGIKTVLDLADTDIRFIRKHF
                     NVVLERTVRELRGEPCLQLEEFAPTKQEIICSRSFGERITDYTSMRQAICSYAARAAE
                     KLRSEHQYCRFISTFIKTSPFALNEPYYGNSASVKLLTPTQDSRDIINAATRSLDAIW
                     QAGHRYQKAGVMLGDFFSQGVAQLNLFDDNAPRPGSEQLMAVMDTLNAKEGRGTLYFV
                     GQGIQQQWQMKRAMLSPRYTTRSSDLLRVK"
     gene            complement(30685..31104)
                     /locus_tag="IRB70_001806"
     CDS             complement(30685..31104)
                     /locus_tag="IRB70_001806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translesion error-prone DNA polymerase V
                     autoproteolytic subunit"
                     /protein_id="HBC0631727.1"
                     /translation="MLFIKPADLREIVTFPLFSDLVQCGFPSPAADYIEQRIDLNQLL
                     IQHPSATYFVKASGDSMIDGGISDGDLLIVDSAITASHGDIVIAAVDGEFTVKKLQLR
                     PTVQLIPMNSAYSPITISSEDTLDVFGVVIHVVKAMR"
     gene            31476..32387
                     /gene="hlyE"
                     /locus_tag="IRB70_001807"
     CDS             31476..32387
                     /gene="hlyE"
                     /locus_tag="IRB70_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415700.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin HlyE"
                     /protein_id="HBC0631728.1"
                     /translation="MTEIVADKTVEVVKNAIETADGALDLYNKYLDQVIPWQTFDETI
                     KELSRFKQEYSQAASVLVGDIKTLLMDSQDKYFEATQTVYEWCGVATQLLAAYILLFD
                     EYNEKKASAQKDILIKVLDDGITKLNEAQKSLLVSSQSFNNASGKLLALDSQLTNDFS
                     EKSSYFQSQVDKIRKEAYAGAAAGVVAGPFGLIISYSIAAGVVEGKLIPELKNKLKSV
                     QSFFTTLSNTVKQANKDIDAAKLKLTTEIAAIGEIKTETETTRFYVDYDDLMLSLLKE
                     AAKKMINTCNEYQKRHGKKTLFEVPEV"
     gene            complement(32594..33040)
                     /locus_tag="IRB70_001808"
     CDS             complement(32594..33040)
                     /locus_tag="IRB70_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309703.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgN family cysteine cluster protein"
                     /protein_id="HBC0631729.1"
                     /translation="MSDVPFWQSKTLDEMSDAEWESLCDGCGQCCLHKLMDEDTDEIY
                     FTNVACRQLNIKTCQCRNYERRFEFEPDCIKLTRENLPTFEWLPMTCAYRLLAEGKDL
                     PAWHPLLTGSKAAMHGERISVRHIAVKESEVIDWQDHILNKPDWAQ"
     gene            complement(33132..33791)
                     /locus_tag="IRB70_001809"
     CDS             complement(33132..33791)
                     /locus_tag="IRB70_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarylacetoacetate hydrolase family protein"
                     /protein_id="HBC0631730.1"
                     /translation="MYQHHNWQGALLDYPVSKVVCVGSNYANHIKEMGSAVPEEPVLF
                     IKPETALCDLRQPLAIPSDFGSVHHEVELAVLIGATLRQATEEHVRKAIAGYGVALDL
                     TLRDVQGKMKKAGQPWEKAKAFDNSCPLSGFIPTAEFTGDPQNTTLGLSVNGEQRQQG
                     TTADMIHKIVPLIAYMSKFFTLKAGDVVLTGTPDGVGPLQSGDELTVTFDGHSLTTRV
                     L"
     gene            complement(33863..34156)
                     /locus_tag="IRB70_001810"
     CDS             complement(33863..34156)
                     /locus_tag="IRB70_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgL domain-containing protein"
                     /protein_id="HBC0631731.1"
                     /translation="MFCVIYRSSKRDQTYLYVEKKDDFSRVPEELMKGFGQPQLAMIL
                     PLDGRKKLVNADIEKVKQALTEQGYYLQLPPPPEDLLKQHLSVMGQKTDDTNK"
     gene            complement(34168..34326)
                     /locus_tag="IRB70_001811"
     CDS             complement(34168..34326)
                     /locus_tag="IRB70_001811"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631732.1"
                     /translation="MAFLRSVKSRRGIFAGGSLIKGAWTEQTAEIYSWLACGAGFIDV
                     SLCQNLAS"
     gene            34397..34798
                     /locus_tag="IRB70_001812"
     CDS             34397..34798
                     /locus_tag="IRB70_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PPC domain-containing protein"
                     /protein_id="HBC0631733.1"
                     /translation="MKIKGISKAVLLLALLTSTSFAAGKNVNVEFRKGHSSAQYSGEI
                     KGYDYDTYTFYAKKGQKVHVSISNEGADTYLFGPGIDDSVDLSRYSPELDSHGQYALP
                     ASGKYELRVLQTRNDARKNKTKKYNVDIQIK"
     gene            complement(34901..35269)
                     /locus_tag="IRB70_001813"
     CDS             complement(34901..35269)
                     /locus_tag="IRB70_001813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcgJ family protein"
                     /protein_id="HBC0631734.1"
                     /translation="MNMMRIIYIGLSGVGMMFSSMASGNDAGGLQSPACGVVCDSYIC
                     VNSDGISPELTRKYLGEKAAENLQSVQGYDPSEFTFSNGVFCDVKEKLCRDDRYFGVD
                     GKRSGKINQTTTKMLFMCRE"
     gene            35789..36484
                     /gene="minC"
                     /locus_tag="IRB70_001814"
     CDS             35789..36484
                     /gene="minC"
                     /locus_tag="IRB70_001814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinC"
                     /protein_id="HBC0631735.1"
                     /translation="MSNTPIELKGSSFTLSVVHLHEAEPKVIHQALEDKIAQAPAFLK
                     HAPVVLNVSALEDPVNWSAMHKAVSATGLRVIGVSGCKDAQLKAEIEKMGLPILTEGK
                     EKAPRPAPAPQAPAQNTTPVTKTRLIDTPVRSGQRIYAPQCDLIVTSHVSAGAELIAD
                     GNIHVYGMMRGRALAGASGNRETQIFCTNLMAELVSIAGEYWLSDQIPAEFYGKAARL
                     QLVENALTVQPLN"
     gene            36508..37320
                     /gene="minD"
                     /locus_tag="IRB70_001815"
     CDS             36508..37320
                     /gene="minD"
                     /locus_tag="IRB70_001815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020801817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum site-determining protein MinD"
                     /protein_id="HBC0631736.1"
                     /translation="MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVIDFDIGLR
                     NLDLIMGCERRVVYDFVNVIQGDATLNQALIKDKRTENLYILPASQTRDKDALTREGV
                     AKVLDDLKAMDFEFIVCDSPAGIETGALMALYFADEAIITTNPEVSSVRDSDRILGIL
                     ASKSRRAENGEEPIKEHLLLTRYNPGRVSRGDMLSMEDVLEILRIKLVGVIPEDQSVL
                     RASNQGEPVILDINADAGKAYADTVERLLGEERPFRFIEEEKKGFLKRLFGG"
     gene            37324..37590
                     /gene="minE"
                     /locus_tag="IRB70_001816"
     CDS             37324..37590
                     /gene="minE"
                     /locus_tag="IRB70_001816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division topological specificity factor
                     MinE"
                     /protein_id="HBC0631737.1"
                     /translation="MALLDFFLSRKKNTANIAKERLQIIVAERRRSDAEPHYLPQLRK
                     DILEVICKYVQIDPEMVTVQLEQKDGDISILELNVTLPEAEELK"
     gene            complement(37956..38300)
                     /locus_tag="IRB70_001817"
                     /pseudo
     CDS             complement(37956..38300)
                     /locus_tag="IRB70_001817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
     gene            complement(38335..38454)
                     /locus_tag="IRB70_001818"
     CDS             complement(38335..38454)
                     /locus_tag="IRB70_001818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBC0631738.1"
                     /translation="MPLSYAGYHYFIMMSLMSGEHNTPALSLQDQSPGLVPAG"
     gene            complement(38415..38600)
                     /locus_tag="IRB70_001819"
     CDS             complement(38415..38600)
                     /locus_tag="IRB70_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631739.1"
                     /translation="MSRKYSSAMITLVILFCRRPHCRKISVQQYYQKRVIFYPTTLQR
                     TAFKKCLFLMRDIIISS"
     gene            38701..38874
                     /locus_tag="IRB70_001820"
     CDS             38701..38874
                     /locus_tag="IRB70_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631740.1"
                     /translation="MSYFSFEIILIPVKNIIPIITVTLILNYLNNSERSLVKPILIED
                     EIIVCATYLIPDI"
     gene            38876..39220
                     /locus_tag="IRB70_001821"
     CDS             38876..39220
                     /locus_tag="IRB70_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415690.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper family protein"
                     /protein_id="HBC0631741.1"
                     /translation="MKKKILAFGLISALFCSTPAMADMNRTTKGALLGAGVGLLTGNG
                     VNGVLKGAAVGAGVGAVTEKGRDGKNARKGAKVGAAVGAVTGVLTGNGLEGAIKGAVI
                     GGTGGAILGKMK"
     gene            39224..39559
                     /locus_tag="IRB70_001822"
     CDS             39224..39559
                     /locus_tag="IRB70_001822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YmgD family protein"
                     /protein_id="HBC0631742.1"
                     /translation="MMMKKFALLAGLFVFAPMTWAQDYNIKNGLPSETYITCAEANEM
                     AKTDSAQVAEIVAVMGNASVASRDLKIEQSPELSAKVVEKLNQVCAKDPQMLLITAID
                     DTMRAIGKK"
     gene            complement(39615..41936)
                     /locus_tag="IRB70_001823"
     CDS             complement(39615..41936)
                     /locus_tag="IRB70_001823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBC0631743.1"
                     /translation="MQGNNTIVTTGDYSIGLLSQTNGNLNTDTIIRVNTDGSVNPHLS
                     DEGITFIVTAGNHAVGVLACASPGSARACVSSLDEESTADTGSNENNTKAKLDMAKGE
                     ITTHGTESYAAYANGTVVKAGSKLDYTNASVTLTDVDITTHGDNAHAIAARQETVSFN
                     QGEIHTTGPDTAIAKIYNGGKVTLKNTSAVAHQGAGFVLESSINGQEATVDILSGSSL
                     RSANEILYNKNETSNVTITDSEVSSAADVFINNIKGHLAIDASNSKITGSANLSTDDS
                     THTYLSLSDNSTWDIKTDSTVSKLTVDNSTVYISRADGKDFEPTRLTITENYVGNNGV
                     LHLRTELGDDNSATDKVVINGNTSGTTRVKVTNAGGSGAYTLNGIEIISVEGESNGEF
                     IKDSRIFAGAYEYSLTRGNTEATNKNWYLTNFQATSGGETNSGGSSAPTVAPTPVLRP
                     EAGSYVANLAAANTLFVMRLNDRAGETRYIDPVTEQERSSRLWLRQIGGHNAWRDSNG
                     QLRTTSHRYVSQLGADLLTGGFTDSDSWRLGVMAGYARDYNSTHSSVSDYRSKGSVRG
                     YSAGLYATWFADDISKKGAYIDAWAQYSWFKNSVKGDELAYESYSAKGATVSLEAGYG
                     FALNKSFGLEAAKYTWIFQPQAQAIWMGVDHNAHTEANGSRIENDANNNFQTRLGFRT
                     FIRTQEKNSGPHGDDFEPFVEMNWIHNSKDFAVSMNGVKVEQDGARNLGEIKLGVNGN
                     LNPAASVWGNVGVQLGDNGYNDTAVMVGLKYKF"
     gene            complement(42663..42881)
                     /locus_tag="IRB70_001824"
     CDS             complement(42663..42881)
                     /locus_tag="IRB70_001824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001065870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631744.1"
                     /translation="MNNSNNLDYFTLYIIFSIAFMLITLLVILIAKPSTGLGEVLVTI
                     NLLNALVWLAINLVNRLRERLVSHRDQH"
     gene            complement(43013..44536)
                     /locus_tag="IRB70_001825"
     CDS             complement(43013..44536)
                     /locus_tag="IRB70_001825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707066.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBC0631745.1"
                     /translation="MRNTLIPILVAICLFITGVAILNIQLWYSAKAEYLAGARYAANN
                     INHILEEASQATQTAVNIAGKECDLEEQYQLGTEAALKPHLRTIIILKQGTVWCTSLP
                     GNRVLLSRIPVVPDSNLLLAPAIDTVNRLPILLYQSQFADTRILVTISDQHIRGALNV
                     PLKGVRYVLRVADDIIGPTGDVMTLNGHYPYTEKVHSTKYHFTIIFNPPPLFSFYRLI
                     DKGFGILIFILLIACAAALLLDRYFNKSATPEEILRRAINNGEIVPFYQPVVNGREGT
                     LRGVEVLARWKQPHGGYISPAAFIPLAEKSGLIVPLTQSLMNQVARQMNAISSKLPEG
                     FHIGINFSASHIISPTFVDECLNYRDSFTRRDLNLVLEVTEREPLNVDESLVQRLNIL
                     HENGFVIALDDFGTGYSGLSYLHDLHIDYIKIDHSFVGRVNADPESTRILDCVLDLAR
                     KLSISIVAEGVETKEQLDYLNQNNITFQQGYYFYKPVTYIDLVKIILSKPKVKVVVE"
     gene            complement(44868..45116)
                     /locus_tag="IRB70_001826"
     CDS             complement(44868..45116)
                     /locus_tag="IRB70_001826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631746.1"
                     /translation="MNNSIPERFILQCALFKNLEREVFMTHGYVDSYIIDQALRLRLK
                     DETSVILSDLYLQILQYIEMHKTTLTDIIINDRESVIS"
     gene            complement(45229..45495)
                     /gene="ariR"
                     /locus_tag="IRB70_001827"
     CDS             complement(45229..45495)
                     /gene="ariR"
                     /locus_tag="IRB70_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm/acid-resistance regulator AriR"
                     /protein_id="HBC0631747.1"
                     /translation="MLEDTTIHNAIADKALSSYFRSSGNLLEEESAVLGQAVTNLMLS
                     GDNVNNKNIILSLIHSLETTNDILKADVIRKTLEIVLRYTADDM"
     gene            complement(45524..45796)
                     /locus_tag="IRB70_001828"
     CDS             complement(45524..45796)
                     /locus_tag="IRB70_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YmgA"
                     /protein_id="HBC0631748.1"
                     /translation="MKTSDNESTKYEITGQAVLQILRMKINFSLQTLIKQLLVMKSVE
                     ENAFRRDLIDSIIRDFSNSDTGGPNRRTAITDNKSIFNGKKINRIH"
     gene            complement(45839..46075)
                     /locus_tag="IRB70_001829"
     CDS             complement(45839..46075)
                     /locus_tag="IRB70_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component-system connector protein YcgZ"
                     /protein_id="HBC0631749.1"
                     /translation="MHQNSVTLDSAGAITRYFAKANLPTQQETLGEIVTEILKDGRNL
                     SRKSLCAKLLGRLEQATGEEEQKHYNALIGLLFE"
BASE COUNT        11931 a        11536 c        10887 g        11823 t
ORIGIN      
        1 tattttttta atgactaata aatgccattt actctctgac tccacaacaa taaggaaggg
       61 ataatgtttt gattcatgtc ctgacatcac gctggttaga tccgctgcgg gattgtattc
      121 cgtacggctg gtaactatgg cgtaatgaaa gacttcaccg gagctatggc gaactttctt
      181 ggtttctctg tcgcaccacg gcttaccggg atacttacac ttcattaggg catatccctg
      241 gaccgaacac agattgcccc ccacttatgc ccccaactgt gatttgattc cagttgatac
      301 caaaagataa ggtacgggct agaaactagc cgtatacggg ctttgagttg gtttcggtag
      361 acttggcaaa agttttaaat ggtgccgatt atggagtcga acatacgaac tgttcatttc
      421 gaaagcgagc caattccaaa atgagtacaa gaatgagtat aactaaagaa cagtagaaat
      481 taaaacatca aatatcaata aaatacaata aaagtcatgg ttcaacgtct aattccgcta
      541 atactactct ggcggttaat aacgagccat tatgtgagtt gcacgtaatg gcttttttac
      601 gcctgctacg cgtcttcttt caattctgag ttaccaaaac tcataatcag actcctgaca
      661 atattaacaa tgcagctttt atgtgataac aatcacagtg cattaaccgt tcaagagttt
      721 gtcatgaaaa aaacatttac cttcagcctg ttagcaattg tctttgcaag cctgttgagt
      781 gcttgtgttc cccaccatca tcaccgccac agcgatggcc ctcgtggtcc tgcgccctcc
      841 gataaggcaa tgccaccttc aaatggtgga ccaaatcacg gcagtcatgg tggctattaa
      901 ttagcaattc atagcgggaa agtacatact ctcccgctat ccacggcgct taaactgccc
      961 tgcatcaatg ccatgttgct tcattttccg ccacagcgta gtgcggccga ttccaagtaa
     1021 agccgacatt tcctgaatgc gaccgcctgt gacctgggct gcgttaataa ttgcctcttt
     1081 ttcaacttcc gcaaatgaca gactggtgga aaggcgagtg gcgctgacat catctgtcgc
     1141 ctgctcggta aacagatgtt caggtaaatc actgacgcga atgcgcccgt tatcactact
     1201 cagtgcaaga ttctcgatga cgctgtaaag ttcaaaatcg ttgcctggcc atgcacaaga
     1261 aaccaggcga gcgagggcat cgtcatcaat tttcagccgc gtagagatgc gtttttcaag
     1321 gctgcgtaat ttgttattca ccagcgccgg aatgctgcca cgccgcatac gcagaggcgg
     1381 gatggtaatt tcaaatgcat gcagcgcgta atacagctgg cgactaaagc gattttgttc
     1441 caccagcatt gccaggtccg cggtcgttgt ggcaatcact ttgacatcaa tgggtattaa
     1501 acgccgcgca tccagtcgcg tgataacacc ctgcttgata acctgaagca aagcagactg
     1561 taactccacc gccagatatt caatcttttc aagaaacagc gtgccgccgt gcgccagttc
     1621 cagtcgactc agacgaccat tttcattgtc cgtgcgatcg ccgccaataa attcttccgc
     1681 cagcgccgca tcaccatata actcacaatt gacggcgata taaggccccg ctgcacgctc
     1741 actttcatta tgaattgcct gacttagcag tgccttgccc acgccctctt ctccacaaag
     1801 caggacagga aagctactgc gcgccgcctg gcgaccaaaa tgaatcaagc ggcgggtttg
     1861 cggatcgtcc tgtggcatat gagcgaaagt atggttgact cttcctaatt gactggtcat
     1921 taactgccgc atctgttcca caggatggag caacaaaata aagctggttc cctgcgtttc
     1981 tattatcggt ttaagggtta tcaccgcatc aataaactgg tgctgacttt caaaggttgc
     2041 ttctacgtgt ttgagcggat gtgcctgttt tattgcttgt tgcaatacgg cgggtaacgt
     2101 taagagttca gtgattgctc gtccctgact tgccgtcgcg tcaaggcgca agactcgcgc
     2161 cgcctgggcg ttgataaatt gcaaattacc ctgctcgtcc cagctaatca cgccatcatc
     2221 catactttct aacagggcat taagttgatt taaatggcgg ttagtttcag cgagcaaact
     2281 gtccgtcagc agtaaatttc cgacctcgcg tgcgattgcc aacgtcaacg gcaaatcagc
     2341 tgcggtagtt tgttcaaccg gacacgccag cgctattgtt cccgtcaatc ggcccttgct
     2401 gtcaaacaac ggcgttgcgc aaaaggccca gttccagagt gcctgtttga aatgttgatc
     2461 ggccatcgtt ttcacggcct gaccagagat agccgctaac gatagcgcac aagtaccaat
     2521 aattccctcg gcgcaatacg tgccgtcatt gaatcccagt gtacttagtt gctgcaaggt
     2581 ttgcggatcg ccattacggc tgagaatgca ggcggtttca tcgaggataa gcaacgcaca
     2641 cgctcgcggt gccatatatt cccaggcatc ttccagcgca gcctgcccga gcgtcagcat
     2701 cgctttctta cgccgataaa tagaagcaaa tgtcacgccc tgggcctggt gtggtacgtt
     2761 ccatgtctcc cgtttcatca gcttattgca tctctcccag gaggttgcaa ttaagggaga
     2821 tatgtcccga ccatcgttgt taaaagcgcc actcatatcc cgcatccctt atgacaaaag
     2881 gtgttccggc tcgcaatttt aagtattaat acacgtaaaa gtttcaatat ggaacattca
     2941 ttaaagaata tgtttcacta tgaaacataa tttgggctaa ttttcttttc ccttgcctga
     3001 tgcacaatgg attcatcggc agtcagtggt cgccgtgtcg ttgaacatca tccatgccct
     3061 accgtaattg ctggagcaaa ataatgaaaa aattgatcaa tgatgtgcaa gacgtactgg
     3121 acgaacaact ggcaggacta gcgaaagcgc atccatcgct gatactgcac caggatccgg
     3181 tgtatgtcac ccgagctgat gcccccgtgg caggaaaagt cgccctgctg tcgggtggcg
     3241 gcagcggaca cgagccgatg cattgtggtt atatcggtca ggggatgctt tctggggcct
     3301 gtccgggcga aattttcacc tcaccgacgc ccgataaaat ctttgaatgc gccatgcaaa
     3361 ttgatggcgg cgaaggtgta ctgttgatta tcaaaaatta caccggcgat attcttaact
     3421 tcgaaacagc aaccgagtta ctgcacgata gcggcgtaaa agtgaccact gtggtcattg
     3481 atgacgacgt tgcagtaaaa gacagtcttt ataccgccgg gcggcgcggc gttgccaaca
     3541 ccgtattaat tgaaaaactc gtaggtgcag cggcggagcg tggcgactca ctggacgcct
     3601 gtgcggaact ggggcgtaag ttgaataatc aaggccattc aataggtatc gctctcggtg
     3661 cctgtaccgt tcctgccgcg ggcaaacctt cttttaccct ggcggataat gagatggagt
     3721 ttggcgtcgg cattcatggt gagccaggta ttgaccgccg ccccttctct tcccttgatc
     3781 aaaccgtcga tgaaatgttc gacaccctgc tggaaaatgg ctcataccat cgcactttgc
     3841 gtttctggga ttatcaacaa ggcagctggc aggaagaacc acaaaccaaa caaccgctcc
     3901 agtctggcga tcgggtgatt gcgctggtta acaatcttgg cgcaactccg ctttctgagc
     3961 tgtacggcgt ctatagccgc ctgaccacac gttgccagca agcgggattg actatcgaac
     4021 gtaatttaat tggcgcgtac tgcacctcac tggatatgac cggtttctca atcaccttac
     4081 tgaaagttga tgacgaaacg ctggcactct gggacgcccc tgtccacacc ccggccctta
     4141 actggggtaa ataaggagaa agcaatgtca ctgagcagaa ctcaaattgt taactggctc
     4201 actcgttgtg gcgatatttt cagcaccgag agcgagtatc ttactggact ggatcgcgag
     4261 attggcgacg ctgaccacgg gctaaatatg aatcgaggct ttagcaaagt ggtggaaaaa
     4321 ctccctgcta tcgcagataa agatatcggt ttcattctca agaataccgg catgacgcta
     4381 ctttccagcg tcggaggtgc cagtggtccg ctgttcggta ccttctttat ccgcgccgca
     4441 cagacaaccc aggcacggca aagcctgacg ctggaagagc tttatcagat gttccgcgat
     4501 ggcgcggacg gcgtaatcag tcgcgggaaa gccgaacctg gcgataaaac catgtgtgat
     4561 gtgtgggtgc cggtggtgga atcgttacgt cagtcctgcg agcaaaatct ccctgttccg
     4621 gcggcgctcg acgctgccag tagcatcgcc gaatccgctg cacaaagtac gattacgatg
     4681 caagcccgca aaggccgcgc cagttatctc ggtgaacgca gtattggtca ccaggatccc
     4741 ggcgcgacct cggtgatgtt tatgatgcaa atgttggcgt tagccgcaaa agagtaagga
     4801 attggtgatg gtaaacctgg tcatagtttc acatagcagc cgactgggag aaggtgtcgg
     4861 tgaattagcc cgtcagatgt taatgagtga taattgtaaa atcgccattg ccgcgggaat
     4921 tgacgatcca caaaatccca ttggtaccga tgccgtcaaa gtgatggagg ccatcgaatc
     4981 tgttgccgat gccgaccatg tgctggtcat gatggatatg ggaagcgcat tattgagtgc
     5041 tgaaactgcg ctggaattgc tggctcccga gatcgccgca aaagtacgtt tgtgtgctgc
     5101 gccgttggtc gaaggtacac tggcagcaac ggtcagcgcg gcctcggggg cggatatcga
     5161 caaagtcatc tttgacgcca tgcatgcgct ggaagccaaa cgtgaacaac tgggtttacc
     5221 gtcctccgac actgaaatct ctgacacatg tcctccgtac gatgaagaag cccgttctct
     5281 gtcggtggtc ataaaaaacc gtaacggcct gcatgtacgt ccggcctccc gactggttta
     5341 taccttatcg acatttaatg ccgatatgtt gctggagaaa aacggcaaat gcgttacacc
     5401 ggagagtatt aatcagattg cgttactaca agttcgctat aacgatacgc tgcgcctgat
     5461 tgcgaaagga ccagaagctg aagaggcact gatcgctttc cgtcagctgg ctgaagataa
     5521 ctttggtgaa acggaggaag ttgctccacc tactctgcgt cccgttccgc ctgtttcggg
     5581 taaagccttt tattatcaac ctgttttatg tacggtacag gcaaaatcaa tcctgaccgt
     5641 ggaagaagaa caagaacgat tacgccaggc cattgacttc acgttattag atctgatgac
     5701 gttaacagcg aaagcagaaa ccagcgggct tgacgatatt gccgcaatct tttctggtca
     5761 ccatacactg ttagatgatc cggaactgca ggcggcggca agcgaactcc ttcagcatga
     5821 acattgcacg gcggaatatg cctggcagca cgttcttaaa gaacttagcc agcaatacca
     5881 acagctggat gatgaatatc tacaggctcg ctatatcgat gtggacgatc ttctgcatcg
     5941 caccctggtc cacctgaccc aaacgaaaga agaactcccg cagtttaact cgccaactat
     6001 tctactggcg gagaacattt atccctccac agtactgcaa ctggatccag cggttgtaaa
     6061 aggtatctgc cttagcgccg gaagtccgct atcccacagt gccctaatcg cccgtgaact
     6121 gggaattggc tggatttgcc agcagggtga gaaactgtat gcgatacaac cagaagaaac
     6181 gctaacgctg gacgttaaaa cgcaacgttt caaccgtcag ggttaaacca ccgttcggat
     6241 ggcatcattc tgatgtcatc cggcaattta ctctgcactg atgtttttta actacctgtt
     6301 atatttttca ccaaattatg atgatttttc ttcgctaatc gcgaacccaa cgtcgctggc
     6361 tgactaataa acagatgtta ttttatcact ctatttcgcc gttatttatc cctttaattc
     6421 ccttttctaa aatgtctgtc agttcgcaga atgtgatttc gatcatgcag ctagtgcgat
     6481 cctgaactaa ggttttctga tacttgaata ccgttttatt cggtttcgcc aaaggagaat
     6541 gattgatgaa atcccccacc ccttctcgcc cgcaaaaaat ggcgttaatt ccagcctgca
     6601 tctttttgtg ttttgctgcg ctatcggtgc aggcagaaga aacatcggta acgccacagc
     6661 cgcctgatat tttattaggg ccgctgttta atgatgtgca aaacgccaaa ctttttccgg
     6721 accaaaaaac ctttgccgat gccgtgccga acagcgatcc gctgatgatc cttgctgatt
     6781 atcggatgca gcaaaaccag agcggatttg atctgcgcca tttcgttaac gtcaatttca
     6841 ccctgccaaa agagggcgag aaatatgttc cgccagaggg gcagtcactg cgcgaacata
     6901 ttgacggact ttggccggta ttaacgcgtt ctaccgaaaa caccgaaaaa tgggattctc
     6961 tgttaccgct gccggaacct tatgtcgtgc cgggcggacg ttttcgcgag gtatattact
     7021 gggacagtta cttcaccatg ttaggacttg ccgaaagcgg tcactgggat aaagtcgcgg
     7081 atatggtggc caattttgct catgaaatag acacttacgg gcatattccc aacggcaacc
     7141 gcagttacta tttaagccgc tcgcagccgc ccttctttgc cctgatggta gagttactga
     7201 cgcagcatga aggcgacgcc gcgttgaaac aatacctgcc gcaaatgcaa aaagaatatg
     7261 cttactggat ggacggtgtt gaaaacctgc aagccggaca acaggaaaaa cgcattgtca
     7321 aacttcagga tggtaccctt ctcaaccgct actgggacga tcgcgatacg ccacgaccag
     7381 agtcatgggt ggaagatatt gccaccgcca aaagcaatcc gaatcgacct gccactgaaa
     7441 tttaccgcga cctgcgctct gccgctgcgt ctggctggga tttcagctca cgctggatgg
     7501 acaatccgca gcagttaaat accttacgca ccaccagcat cgtaccggtc gatctgaaca
     7561 gcctgatgtt taaaatggaa aaaatcctcg cccgcgccag caaagctgcc ggagataacg
     7621 cgatggcaaa ccagtacgaa acgctggcga atgcccgtca aaaagggatc gaaaaatacc
     7681 tgtggaacga tcaacaaggc tggtatgccg attacgacct gaaaagtcat aaagtgcgca
     7741 atcagttaac cgcggccgcc ctgttcccgc tgtacgtcaa tgcggcagcg aaagatcgcg
     7801 ccagcaaaat ggcgacggcg acgaaaacac atctgctgca acccggcggc ctgaacacca
     7861 cgtcggtgaa aagtggacaa caatgggatg cgccaaacgg ctgggcaccg ttgcagtggg
     7921 tcgcgacaga aggattacaa aactacgggc aaaaagaggt ggcgatggac attagctggc
     7981 acttcctgac caatgttcag cacacctatg accgggagaa aaagctggtg gaaaaatatg
     8041 atgtcagcgc caccggaacg gggggcggcg gtggcgaata tccattacag gatggctttg
     8101 gctggaccaa tggcgtgacg ctgaaaatgc tggatttgat ctgcccgaaa gagcaaccgt
     8161 gtgacaatgt tccggcgacg cgtccactca gtgaatcaac aacacaaccg ctaaaacaaa
     8221 aagaggcgga acctacgcct taactttact gtatatcgag caatgccatt acatgcataa
     8281 aattggcatt gctctttctt caccacgaaa taccactctt tctacggtct atgcctttat
     8341 tttcttttat tagagaagat tttaatttta ttttatcaac ttgttaatca ttacacctct
     8401 atttatattt tcccccactc cccattctcc ctgacaattt tcttgtggaa caaagtgtta
     8461 tttaagcaac aagcaaatca ttctgtctct ttagacaaat tttgacatca aacatgatct
     8521 ttttcgctat atgtgtaagt atatagcggt tttaattatc aggatattac ttatgtcact
     8581 aaccagacgg aggtttacac agattcttgc gtcgacattg ttcctgcatc atctgccgtc
     8641 ctttgcacaa tcagtcaaat tctgggcctc actgacgctt cccgaagccc aaaacattac
     8701 acgcatcgtc agcgcaggcg cgcccgccga tttactattg ctggctgtcg cgccagaaaa
     8761 aatggtcggt ttttcctctt ttgattttgc ccgtcaggca ttaattccat tgccagagca
     8821 cattcgccag ttccccaggc tgggacgact cgccgggcgc gccagcacac tctcgctgga
     8881 agggcttatg gcgttacatc ccgatttggt cgttgattgc ggcaatacgg atgaaacctg
     8941 gatctcccag gcacggcagg ttagcgaaca gacacaaata ccctggttat tgcttaacgg
     9001 gaaactggaa caatcagcag aacagttaac aacgcttggc aaaacgttag gcgaagagca
     9061 ccgcgccaca gaacaagcca atctcgccag ccgcttcgtt ggtgaagctc aggcattcgc
     9121 cacctcaccc gccgctaacc tcagctttta tgctgcgcgc ggtcctcgag ggctggaaac
     9181 gggcttacag ggttcgttgc ataccgaggc ggcggaatta ttaggtttgc ataacgtcgc
     9241 gcaaatagcc gatcgccacg gtctgacaca ggtttccatg gaaaatctcc tgcgctggca
     9301 gccggatatt attctggttc aggaggccgt tactgcagat tttattcgtc gtgatcctct
     9361 ctggcagggc gtgaaagcgg ttgcggaaca acgcatctta tttttaagtg gcctgccctt
     9421 tggctggctg gatgccccgc cgggaatcaa ccgtcttctg ggattacgca gacttcacgc
     9481 ctggctggat cccgccatca atcgtcagtt taaaagtgac atgcaacatt atgcccaact
     9541 gttctggcat tgttcactca gtgacgccga ctatcaaaaa ttggtggcga actaatgaga
     9601 accgtaaacg gatgtatttt gctgctggca gctatcagta tcacttttgc cgccgtaagt
     9661 ggggcttatc atctcgatat gcagcaactg ctggcgctca ttcttcgtca agaaaatgtt
     9721 cctgtgcagg aacaaattgt cttctggcaa atccgcgtgc cgcgtattct tgctgcgctg
     9781 tttctgggcg cggcgctggc aggggccgga accacctatc agggaatgtt ccgtaatccc
     9841 ttagtgtcac cggatatttt aggcgtctcc gccggtgccg gacttggtgc ctgcgcggca
     9901 atcctgtggg gattatccat tgtttacatc cagctgtacg cattttgcgg cgggctgatg
     9961 gtggtcgcgg gcgtctggtt gattacgcgt cgggtaaccc gccacgatcc gatcttaacc
    10021 ctggtgctgg taggcattgc gttaggcacg ttgtgcggag cggggatatc gctaataaaa
    10081 acgctggccg atccttacac ccagttaccg tcaattacct tctggttgct gggaggactg
    10141 tccaccgtga ccttacgcga tctctgctat gctgcaccga tcattctcat aggctccttg
    10201 cccctgtttt ttctccgctg gcgcatgaat ttactcacac tttccgacga cgaagcccgt
    10261 tcgctgggac tgaacgtgac acgtctgcgc tttggattga ttgtctgcgc cacactcatc
    10321 accgccagca cggtagcaat agcgggcata attggttggg tcggcctggt cgttccgcac
    10381 attgcccgct tgttgaccgg tcataaccat cagcagctgt tgcccatggc aatgtgtact
    10441 ggcgcgattc tgctcctgct taccgatacg ctggcacgca gcattggaac aacagaaatc
    10501 ccacttggca ttctgaccgc ttttgttggc gcaccgtttt tcctgttttt gttgttacgc
    10561 ggaggtcgcc agtgactttg cttgccgtcc gtcatgcgtc tctgggttac tcccgccatc
    10621 cggtgctacg cgacgtgtcc ttcaccctgt cgcaaggaac aatttgttgt ctgttaggag
    10681 ccaatggttg cggcaaaacc acactcatgc gctccattct tggcgttata ccgttattaa
    10741 aaggcgagat cttactggat agcctccctg tgcagacact cagccatcgc cagcgcgcgc
    10801 aggctattgc ctgggtgccg caggcgcacg acggcatttt tgcttttagt gtgctggata
    10861 tggtgttgat gggcctggcc cccaccatag gcgctttttc cgttcccggt aagcaagaac
    10921 gcctgaaagc aacggagcaa ctggaaaagc tgggcatttt gcatctggcg acacgacgct
    10981 ggaatacgct tagcggcggt gaacgtcagc tggctttaat cgcccgtgca ctcgtccagc
    11041 aaccgcgctt gttattactg gatgagcctg cctccagcct cgatttcggt catcagatcc
    11101 aactactgga cacgctggcg cagctcaaaa ataacggcat gacaatgtta atgtcgactc
    11161 atcatccgct ccatgccaac gccattgccg acagcattat ccaggtagag ccagatggac
    11221 gtgtaacaca aggcttaccg accgaacagt taacaacgaa aaaactggct gccctgtacc
    11281 gggtttctgc cgaccagatt caccatcacc tctctgcaat taagcactaa ggaacaatca
    11341 tgctcattga tgatattgat tttgcagacc tttaccttca gcaactcagg ctggcccatc
    11401 gcacagaaaa aacgccggat cactgggatc aacgggcgga aaaaatggcg gaaaattgcg
    11461 cctcgcctac ggacagctac ctgcaacaac tgaccgctaa aattgatctg caaggcgcac
    11521 aaaccttatt cgatatgggc tgcggaccgg gtaccgtatc gctggcgctg gctgacaaac
    11581 tcacgacgat ttatggcgtt gattacagtc aggggatgct gaacgttgcc gcccgtcgcg
    11641 ccgccgcgct aaaggcagac aatgtccact ggatccagcg cgcctgggaa gaggactgga
    11701 gtgacctgcc acgctgcgat attgccgtgg cttcccgctc cactctggtg gctgatatgc
    11761 gccaggcaat gagcaaactg aataatcagg cacggcttcg cgtctatacg actcatctgg
    11821 tcagcacctc gttcgtctct ccagccattc agcgggcggc tggtcgggaa gtgatcgaat
    11881 tacccaacta tatatttgcg ctcaacgtcc tgtatcagat gggaatttat gcccacgttg
    11941 attttatccg tggacaaaat tgccaacagg ataacagcac ctgggaacgt tttgagcaga
    12001 acgtcagctg gagtattggc gcgcttaacg acgatgagcg tgagcggtta tatcactggt
    12061 atcaacaaca agatgctcgt gccctcgccc ctgccagccg cgactgggcg ctcatctggt
    12121 gggatagcgt accgcaggag gcactgcgat gattttcctt tctcaggcac aaatcgatgc
    12181 gttacttctg gaagatatcc agggcggtga cctgaccacg cgagcattaa atattggaca
    12241 ccagcatggc tatatagagt tttttcaccg tcagggcggc tgcgtcagcg gaatttctgt
    12301 cgcgtgtaag atgttaacta cgctgggatt aactattgat gacgcagtca gcgacggttc
    12361 acaagcgaac gcgggtcagc ggctaatccg tgcgcaaggt aatgccgcag cacttcatca
    12421 gggatggaag gcagtccaga atgtgctgga gtggagttgc ggtgtttctg attatctcgc
    12481 tcaaatgctg gcgttacttc gtgaacgtta ccctgatggc aatatcgcct gcacccgaaa
    12541 agcaattccg ggcacccgct tactggcctc gcaggcaatt ctggctgccg gaggactgat
    12601 tcatcgtgcc ggatgtgcgg aaaccatatt attgtttgcc aaccaccgtc attttcttca
    12661 tgacaatcag gactggtcag gcgcaatcaa tcagttacgt cgccacgcac ccgagaagaa
    12721 aatagttgtt gaagccgaca cgccgaaaga ggcaatcgcc gcgttacgcg cgcaaccaga
    12781 cgtacttcag ctcgacaaat ttaatccgca acaggcaact gaaattgcgc aaatagcacc
    12841 gtcgctggct cctcactgca cgctggctct gaccggcgga attaatctga caacactcaa
    12901 aaattacctc gactgcggca ttcgcctttt tattacctcc gcgccttatt acgcgacacc
    12961 agctgacatt aaagtcagtc tgcaacccgc agcctctatt taattctttg ttaaacggaa
    13021 tttattctat gagactcaaa aaacgttatc tctgcacagc attatcactt gcctttaccc
    13081 agcaggccgt agcggctcag gagagtgaca cgctgaccgt atggtccagt ccggtatcat
    13141 cgacgacgac caccgttctc gatcaaccca ccatgaaggc cctggataaa cagaatgtcg
    13201 ctcaggcatt aagtgtcgtc cccggcgtgg tgctgcaaaa gtcaggtagc cgcaacgaag
    13261 aacaggtcaa agttcgtggc tttgatagtc gtcaggtgcc agtctatttc gacggtgtgc
    13321 ccatttatgt tccctatgac ggcaacctcg atctggcgcg gattctgacc aacaatttgg
    13381 gggcagttga agtttccaaa gggtattcgt cgctgcttca ggggcctaat cagatgggcg
    13441 gagccattaa tatcaccacc cagaagccaa caaaacctct ggaagcaagt ctgggatatc
    13501 gccagggatg gagccgtagc caggacaatg cctacgatat gcatgcttca tttgccgcca
    13561 gcagcgatct ggggtatttg caagtcagcg gtagccagct aaagcaggat tttctcggcc
    13621 tgccgcatgg tgtaaataat gatattgcag gcaaacacgg caagatgatt aattcatcgg
    13681 ctgatgataa acgcggcatt gtgaagctcg gttttacacc acgcgaaaac gatgaataca
    13741 cattgactta cattaagcag gatggtgaaa aagataaccc gccatacagt ggaaatagtg
    13801 gtcaaaaatc acgctactgg cagtggccag agtatgacaa agaaagtttt tattatcagg
    13861 gaacgaccca actaaacgat cgttttaccc tgaaaagtcg gctgtatcgc gacacctttg
    13921 aaaatacgct aatgatgtac aactcgctgg ctgatttgaa aaataaaaaa ggcagctaca
    13981 gccattattc cgattacagc gacggtgccg ggttacaact ggcagccgat gtgcgtgaaa
    14041 acgatctgct gtcgtttgcc gttaactgga aagatgacgt acaccgggaa aaaggtgcgc
    14101 cgcacgccgc ttacgatcgc tatgaagatc gtacctggtc gctcgccagt gaatatcaat
    14161 gggctgctgc cgataatgtc gatgtcgtgg ctggaatcag ctatgactgg cgcgatagcg
    14221 tagaagcgaa aaaacatgag aaagatggca gtatcaccca ttatgacgac aacaatcagt
    14281 cagcttttaa ctggcaggtg atggggaaat accactttgc caatgaagac acgctggcgc
    14341 tttcgtacta tgaccgcaca cgctttccga cgctgaaaga acgctatacc acgtccaaac
    14401 ctgcgtataa ccagatagcg attgttaacc cgcagctcaa accggaacgc gcgcgcgggg
    14461 tggatttaac ctggaatggt gccttcacgc acgactgggg gtttgaggtc agcgtttact
    14521 ataaccgggt gagtgatgcc atcctctcgc acaatatcga tgccgatacc attcaaaatc
    14581 agaacagcgg cacggtggat tacagcggtc tggatgccgg tattaagggg aaaatcagca
    14641 atatactgga tgtaggattg agctacgccc tgatccacgc tgacgccaaa cgcaaagaca
    14701 tcggcaagat aaccgatctg ccaacgcaga caatgaccgc atggatgact ctcaaaccgt
    14761 gggagccgtt aagcgtaacg ctgtcggaag aggcgcgttc ctccagctac agcaacagtg
    14821 acggttcaca aaaagccgcc ggttttgcgg tgacccacat tcgagccgat tacaccttag
    14881 gtcatggctt cagcgtcaat gcgtcggtca ataacctgtt tgataccaaa tatgcctaca
    14941 gtgaagggtt tattgaagaa ggtcgcaatt tctgggcagg tatcgagtat acgttctgat
    15001 gtgaaagcgg atagcggcat ctgtatcact atccgcctta tgaaaatctt attctcttcg
    15061 caggaggcgg aatacgccca gcaccaggat agcgcccacc accgccacca ggaagctgtg
    15121 caaattaaaa ccgctgatgg tgccgccaat gccaaacatg gtcgccagcc agccgccgac
    15181 caccgcaccg actatcccga gaatacaggt caggaaaaat ccaccaccat cacgtcccgg
    15241 catgattagc ttggcgatta tgccggctat caggccaaaa ataatccagg caataattcc
    15301 catgttcagg ccctcgtttc gatgaatcgg acgcaagaaa tgcttacgtc aacgctctaa
    15361 gtataggcaa gggcgggatc gatgctgggc gtatgtcggc tgatttaaga acgacatgta
    15421 aaaaatattc acgcatttgt attaagtttt gttaactgtg accgataaac ctaagacagt
    15481 ttgtcagtca ggagtttttc cgcgtgagtc attaccatga gcagttcctg aaacaaaatc
    15541 cgttagccgt cctgggcgtg ttacgcgatt tgcacaaagc cgcaattcct ttgcgtatta
    15601 gctggaatgg cgggcagctg atcagcaaaa tactggcaat aactccggat aaactggtgc
    15661 tggatttcgg cagccaggcc gaagacaaca tcgccgtgct aaaggcgcag cacattacca
    15721 ttaccgccga aactcagggt gcgaaagtcg agtttactgt tgaacaacta cagcagagtg
    15781 aatacttgca gcttccggca tttattaccg taccgcctcc caccttgtgg tttgtacaac
    15841 gacgccgata tttccgcatc tccgccccac tccatccgcc ttatttttgc cagaccaaac
    15901 tggcggataa cagtacgtta cgtttccgcc tgtatgattt atcgttaggc ggcatgggcg
    15961 cattactgga aacagcaaag cctgccggat tgcacgaagg catgcgcttc gctcagattg
    16021 aagtcaacat ggggcaatgg ggtgtttttc actttgacgc ccagttaatc tccatcagcg
    16081 agcgcaaagt gattgatggc aagaatgaaa ccatcaccac tccccgtctg agcttccgtt
    16141 ttcttaacgt cagcccgacg gtggagcggc aattacagcg gattattttc tctctcgagc
    16201 gagaagcccg gaaaaaagcg gacaaagtgc gcgactgatt tacatcgcgt ccagtgcctg
    16261 ctcaagtttg tagatatagc gcggagcctg cggcgcagga tgatttcgcg ctacgtgatc
    16321 gaggaactcg tcagcatcca gatcgttgat tttgctgatc gcctttttcc gatctgacga
    16381 gaaagtccgt agcagcgcac ctgccccgtt agcgtatgac accaccagcg catattgcag
    16441 taccttcgga tcttcaatac ctgccagcgg gccggtttcc agaatattca ggtaagccgc
    16501 tcccattgaa atattacgct ccggattttt cagctcgctg gtcgtcggct caccactcca
    16561 gcccatacga cgatatacat cacgtccgga ggttgaagct tttatctgca tcaaaccaat
    16621 ggcattcgat ttactcaccg cgttcggatt accacccgat tcgatagcga taatcgccgt
    16681 gatcaattgt ggatcgacgc cccaggctgc accggctttc tggcttattg gcatccactg
    16741 catcgcacgt tgcaccggaa ctttcgcgtt ccacggcggg ttcgtatagt catgctttga
    16801 tgaacaaccc gctaataaca caatcaaaaa ggcaaaccat ctaaatttca cttcttctat
    16861 ccttatagcc tggaatcgcc gttgaggtga caacggcaca cctaagcggc atgatataca
    16921 tttcgtttct gttgtcagca aggaattgcc atgtctctgt ttcacttaat tgccccatcg
    16981 ggttactgca ttaaacagca cgccgcgctg cgtggtatcc agcgccttac cgacgcgggg
    17041 catcaggtca ataacgtcga ggttattgcc cgtcgttgtg agcgttttgc gggtacggaa
    17101 acggagcgtc tggaagatct caattctctt gccagactga ctacccccaa caccatcgtg
    17161 ctggctgtac gcggcggtta cggtgccagt cgtttactgg cagatattga ctggcaggca
    17221 ctagtggctc gccaacaaca tgacccgttg ctcatttgcg gacatagcga ttttaccgcc
    17281 attcagtgcg gtcttctggc gcatggcaat gtcatcacct ttagcggccc catgctggta
    17341 gcaaactttg gcgcggatga actgaacgcc tttaccgagc accatttctg gctggcgtta
    17401 cgcaatgaaa ccttcaccat tgaatggcaa ggggaaggcc cgacatgtca gaccgaaggc
    17461 acgttatggg gaggcaatct cgcgatgctg atttcactga ttggtacacc gtggatgccg
    17521 caaatcgaaa acggtattct ggtgctggaa gatattaacg agcatccttt ccgcgtcgaa
    17581 cgtatgctgt tgcagctcta tcatgctgga attttgccac gtcagaaggc gattattctc
    17641 ggtagcttta gcggcagcac gcctaatgat tatgacgcag gttacaacct ggagtcagtg
    17701 tacgcgtttt tgcgttcccg actgtcgatt ccactcatta ccggcctcga ttttggtcat
    17761 gaacaacgta cggttacgct gccgttgggc gcacaagcca tgcttaataa cactcaggaa
    17821 ggcactcagt tgacgattag cggtcatcct gttcttaaaa tgtaaaaaaa tcacgcttca
    17881 gggctaagta aaacgctgtc tctgccgcta atatggtagg gtttatataa gagacagcgt
    17941 aatcaggagt aaccgaccgt tggatgccac aacaataatt agccttttca tcttaggatc
    18001 catccttgtc accagcagta tattacttag ttcattttct tcccgtcttg gcattcctat
    18061 tctggttatt tttctggcga tcggcatgct ggcaggagtc gatggcgtcg gcggtatccc
    18121 gtttgataat taccccttcg cctacatggt aagtaacctg gcgctggcga ttattttgct
    18181 cgacggcggg atgcgcactc aggccagttc ctttcgtgtg gcgttaggac cggcactgtc
    18241 gctggcgacg ctgggcgtac ttatcacctc aggtttaacc ggcatgatgg cggcgtggct
    18301 gtttaatctt gatttgattg aaggattatt aatcggcgct atcgtcggtt ccaccgatgc
    18361 tgcagcggtc ttttctctgc tgggtggtaa ggggcttaac gaacgtgttg gctcgacgct
    18421 ggaaattgaa tccggcagta atgatccaat ggcggtcttt ctgacgatta cgctgattgc
    18481 gatgatccag caacatgaaa gcagtgtcag ttggatgttc gtggtcgata ttctgcagca
    18541 atttggcctc gggattgtca tcgggcttgg cggtggttat ttactgctgc aaatgattaa
    18601 tcgcatcgcc ctgcccgccg gattatatcc attgctggca ttaagcggcg gtattttaat
    18661 ttttgcttta accacggcgc tggaaggcag cggtattctg gctgtttatc tgtgcggttt
    18721 tctgctgggt aatcgcccga ttcgcaaccg ctacggcatt ctgcaaaatt tcgacggcct
    18781 cgcctggctg gcgcaaatcg ccatgttcct ggtgctgggg ctgttggtta acccaagcga
    18841 tctgctacct attgccattc cggcgctcat tttgtccgca tggatgattt tcttcgcccg
    18901 tcctctttcg gtatttgccg gattgctacc attccgtggc ttcaatctgc gtgagcgcgt
    18961 gtttatcagc tgggtgggat tacgcggcgc ggtgccgatt attctggccg tgttcccgat
    19021 gatggcgggg ctggagaatg cacgtctgtt ctttaatgtc gccttctttg tggttctggt
    19081 ttcactgctc ttgcagggaa catcactctc gtgggcggcg aaaaaagcca aagtggtggt
    19141 tccgcccgtc ggacgtccgg tgtcacgcgt tggcctggat attcatccgg aaaatccgtg
    19201 ggagcagttt gtttatcaat tgagtgccga taaatggtgc gtgggcgcgg cactgcgcga
    19261 tttgcatatg ccaaaagaga cgcgtattgc ggcactgttt cgtgataacc agctgcttca
    19321 tcctaccggc agcacccgac tgcgcgaagg cgatgtattg tgtgtaattg gtcgggaacg
    19381 cgatcttccg gcgctcggta aactgttcag ccagtcgcca ccggtcgcgc tggatcaacg
    19441 cttctttggt gacttcattc tcgaagccag cgccaaatat gctgatgttg cgctgatata
    19501 tggcctggaa gacgggcgag aatatcgtga taagcagcaa acgcttggtg aaatcgtcca
    19561 gcagttgtta ggcgcggcac cggttgtcgg tgaccaggta gagtttgccg ggatgatctg
    19621 gacggtggcc gagaaagaag ataatgaagt gttgaagatt ggcgtacggg tggctgaaga
    19681 ggaagctgaa tcttaaattt aatgcagcat ctatcgccgg atgcgatgct ttactgaccg
    19741 ctgcctgagc ctgtaataaa cttgtcattt cctgattttg atatgttcat tccaacatca
    19801 gaagaaagtt aaattatgga tgacaaacca ttgcaggctc tggctaatga actcaaaaca
    19861 ccggctcaag aaagtcagcg taatggtttc ttccgactgc aacaggtgaa gaaaaaccag
    19921 ccccgcatta ccggtatccc cgtcaaccat caggggcccc tgcctgacat cgcctgaaca
    19981 tattccccca cgcaacctgc cgcactgacg tagcccacac aataggcgtt tcatccgcct
    20041 gtagtaccgg atgcatgagc gatttcttat agttattcct ttgcttaata acgattattt
    20101 ccgggtcgtt cgctctcgta ttttctttaa tacgtcagag ctacctgggc cgtaatacag
    20161 catgtaccag acccgacacg gcatttctga ccagggaaaa agtcaacgat gagtagttat
    20221 atcagcgcaa atgacgtcct gtggctcctt tgcggtgacc acattcacgt ctccggcgct
    20281 gccagaggat atttatttca aggatacgta gcattatggc tagctttaaa gacatctgcc
    20341 cattcgcccc cgccattcct ccatcttccg ttaacccagg cgtacgacgc ccgccagggc
    20401 ggctcttcct gtcggcggaa ctcaagaatc aaattttgca gaacatgaag tatctcagcc
    20461 cgcaaaaatt cagctggggt gatgccccct ggcagatcat tgaccttagt accgcgggca
    20521 aagtgaacat acaggtggac aacaatacca tcatcacgtt ggggactccc ctgaatcagc
    20581 aacataacga gttcatgatg gtcgccaaat ggtgcgaatg ggctatacag caggatggtt
    20641 tgcaagaaaa cctgcaaaaa aaactgcacg aggtcctgga agaaaaccgg caaaacaaac
    20701 agtcagaaat tccccaagaa gacctgaaag aaaggctgaa agaaatcaag gaagatatcc
    20761 tgaaagaaaa ccagtcagca agccagattg aagaccgggc agaagcattg cgcagaatga
    20821 aggaatgtct cataacaaga cagagtatgc tcgatcttag caaccttgga ctgacttcac
    20881 tccctgaaaa tttgcctcca catctgattg aatttaactg cagtagaaac atgttgaccg
    20941 cgttaccgga ggtaatgcca aaggggctga gagtgcttga atgtatggag aactttttga
    21001 tcttgttacc gaaggtgcag cccccgaaac tgatggtact gaagtgctat gaaaactata
    21061 ttatctggct gcctgagctg tcgactaacc tgagagtgat tgactgttct gaaaacttct
    21121 tgcaattttt accgccgtcg atgccccagt acctgtatac actgcgctgt gctttcaaca
    21181 gtattagctt aatacctgat gagatgctgg agaacttgac tcgcctgaag gtatttgact
    21241 gttctagtaa cgatttgatc tcttcaccac ggctgccgcc caaactaatc atatactact
    21301 gtggagaaaa ccagtttaaa actgtaccgg tgccgcagcc ccgaagcctg aaggtgttta
    21361 gctgtaatgg taacccgtgg gacaaagaca atttaccgac gctgctcaaa gccgtcgagg
    21421 gcctgaaaaa ccaggagggt ctggaggagc ttttggactt tttgcacaag gaaggtctgg
    21481 ttgacctgga aggactcgag gagctggagg acctggatga ccttatggat ctggagttcc
    21541 tggatgaccc ggaactcctg gagcgcgtga aggtacagga ggacctggag ctcctggatc
    21601 aacagttggg cctgttgagt ctggaaaaac aacaggactc gcagcctgtt aatcaacaat
    21661 ctgaacatga acccgaatct gcatcaaggg tgaagcgtga tttatctgaa gtcgagttcg
    21721 agtcaacaat gaaacgtaag cgttttatgt agaacgcctg tgcggtgagt tcaggttccg
    21781 gggaaatagt gtccatcatt gtaatggaca ctatcatggg aaatggctct gtcacatcac
    21841 caactacagt tgctgaccag ccggatggat gattttttcg caaccagaag acgctgcctc
    21901 cgatccggct tacaacaagt tacaccgtca caaccgggac acgtaacgcc agcgcgcaca
    21961 tcaactcata gcccaccgtt ccggcagcgg cggcgacatc atcaattttg atctccttgc
    22021 cccacagctc aaccggcgta ccaatccccg cctgcgggca aggcgttaaa tcaaccgcca
    22081 gcatatccat cgagacggtc cccaccgtca tggtgcgcac gccgtccact aaaacaggag
    22141 taccggtagg cgcatggcgc ggataaccgt cggcgtatcc tgcggcgaca atgccgattc
    22201 gctgctcatc gcgcgcagta tagcgaccgc cgtagcccac acgctcgccc gcttttagcg
    22261 tctggacacc aataatctca ctgcttagcg tcatcaccgg gcgtaatccg gtattggcga
    22321 tatcacgcca ctgaccggac ggcgaagcgc catacaaaat aatgccaggc cgaacccagt
    22381 caaaatgcgc ttccgggtgc cacagagtcg ccgccgaatt ggacaacgaa cgccgacact
    22441 ccagcccttc cgccgcctgc tcaatacgcg ccatcgcgct ggaaattcca tcaggatgtt
    22501 ccgcctcggc aaaatgcgac atcagggtca tttcgccaac attcgccatc gcccgcaact
    22561 gctgccagac ggtaagcacg cgatcgggct ggaagcccaa ccgattcatc ccactgttca
    22621 ctttaagata aatatccaac ggcgctttta gccgcgcatt ttgcagtgct ttgagctgcc
    22681 agttgctgtg gacgcaggtg gtcaggcggt actggtcata aatctccaga tcctgtgcat
    22741 ggaaaaatcc ctccagcatc aggatcggtc ctttccagcc gcgctcacgt aacgttattg
    22801 cctcttccag attaagtaat gcaaagccat cggtggcccc tagcgcgctc cagatacgct
    22861 caataccgtg cccgtaagca ttcgctttta ccaccgacca aacgcgcgcg tgcggcgcgg
    22921 cctgccggac aatggacaga ttctgtttta atgcctgcag atcgaggctg gcctgtatcg
    22981 gacgggtcat ctcgtttcct tagctgtgtg cgccatgtaa atggcccggg cgtgatggcg
    23041 taaatccacg gctgtagcgc gctacgctta gatcttcata cgggatcgct ggcgtgcgac
    23101 cagagagcag atcgcttaac aactgaccgg aaccgcaagc catcgtccag ccgagcgtgc
    23161 cgtgaccggt attcagccac agatttttaa agcgtgtacg cccgacaacc ggcgtgccgt
    23221 ctggcgtcat cgggcgcaga ccagtccaga aagtcgcctg ctcgacatga ccgccgcgtg
    23281 gatagagatc gcgaaccacc atctccagcg tttcacgacg cggttgcaac agctcggtgt
    23341 taaagccaac aatttccgcc attccgccaa cacgaatgcg gttatcgaaa cgggtaatgg
    23401 cgattttgta ggtttcatca agaatggtgg ataccggcgc accatcttcc tgcgcaatgg
    23461 gaatggtcag cgagtagcct ttcaaaggat acaccggaat atcaactatg cctttgagca
    23521 tcgccgtcga gtaagaacca aacgccatca catacgcatc ggccttaatc acttcatcgc
    23581 cacacttcac gccgtagatt tgctcgccgt cgcaaagtag ttggtcaacg ggcgtattaa
    23641 agcggaattt aacccccgcc tgctccgcca tccgcgccag attctgggta aacagctggc
    23701 agtctccggt ttcatcattg ggcagctgga gcccccccgt cagtttgtgc gccacttctg
    23761 ccagcgcggg ctccacttcc gccagacggc tggattccag cagctggtac ggtacgccgg
    23821 catcttccag cacggcgata tcgcgggtcg cattttcata ctgttgttcg gtacggaaca
    23881 gttgcagcgt cccaccctga cgcccttcat actgaatatt ggtttcggcg cgcaatgctt
    23941 tcaggcaatc acggctgtat tccgccagac gcaccatccg ccctttgttt tccatgtagt
    24001 ggctggtgtc gcagttacgt aacatttgcc acatccattt caactggaac tgcgtaccgt
    24061 cgagacgaac cgccagcggc gcatggcgct ggaacatcca tttaatcgct tttaaaggca
    24121 cacctggtgc cgcccacggt gctgcatatc cgggggagat ttgcccggca ttcgcggcac
    24181 tggtttccag ggcggccccc ggctcccgat caatgacggt gacctcatgt cctgcctgat
    24241 ttaagtacca ggcgctggca acgcctacca caccacttcc cagtatgaca actcgcatag
    24301 ccactccgat aacggtagat acagtaaaag aataataatc taattacatc ttgataactc
    24361 agttgaaaat attattcaac atatggcttt tttatggtga gctggctcac atctccctga
    24421 ctctgcggca atatggcgtc tttagtatct cctgctgaac gcccttttta tccagcataa
    24481 aattccgttc agaagcggat tagtggcact ctaataataa gaaatcgcaa agaaaaaaat
    24541 tctccggcga cgcggttttt aacaggtgtt ctatgcttga aatgaggtgc tccacacaga
    24601 gagcgccgac aacaatgagg tgcgcgtatg gcgacgatcg attctatgaa taaggacacc
    24661 acacgtttga gcgatggacc cgactggacg ttcgacctgc tggatgttta tctggcagag
    24721 atagaccggg tggcgaaact ctaccggctg gatacctacc cgcaccagat tgaagtgata
    24781 acctcagaac agatgatgga tgcctactcc agcgtcggca tgccaattaa ctatccgcac
    24841 tggtcattcg gtaaaaagtt tatcgagact gaacggctgt ataagcacgg tcagcaagga
    24901 ctggcctatg aaatcgtcat taactctaac ccgtgtatcg cttacctgat ggaagaaaac
    24961 accattacca tgcaagcgct ggtgatggca cacgcctgct atgggcataa ctctttcttc
    25021 aaaaacaatt acttattccg tagctggacc gacgccagtt cgattgtcga ttatctgatt
    25081 tttgcccgta aatatattac cgagtgcgaa gaacgttatg gcgttgatga agtagaacgg
    25141 cttctggact cgtgccacgc gctgatgaac tacggcgtgg accggtacaa acgcccgcaa
    25201 aaaatctcgc tgcaagaaga gaaagcccgg cagaaaagtc gcgaagagta tctgcaaagt
    25261 caggtcaata tgctctggcg taccctgccg aagcgcgagg aagagaaaac ggttgctgaa
    25321 gcgcgccgct atccgtccga accacaagaa aacttgctct attttatgga gaaaaatgcg
    25381 ccactgctgg aatcatggca gcgtgaaatc ctgcgtattg tgcgtaaggt gagccagtat
    25441 ttttatccgc aaaaacagac tcaggtgatg aacgaaggct gggcgacctt ctggcactac
    25501 accatcctta accatctgta tgatgaaggg aaagtaacgg aacgttttat gctggagttt
    25561 ttgcacagcc acaccaatgt ggtcttccag ccgccctata acagcccgtg gtacagcggc
    25621 atcaacccgt atgccctcgg gttcgccatg ttccaggata ttaaacggat ttgtcagtcg
    25681 ccaacggaag aagacaaata ctggttcccg gatatcgccg gttctgactg gctggacaca
    25741 ttacattttg cgatgcgtga tttcaaagat gagagcttta tcagtcagtt cctatcaccg
    25801 aaagtgatgc gtgatttccg cttcttcacc gtgctggacg acgatcggca taattatctg
    25861 gagatttccg ctattcataa tgaagaaggt tatcgggaga tccgtaaccg gttatcgtcg
    25921 caatataatt taagtaatct ggagccgaat attcagatct ggaacgtgga tttgcgcggc
    25981 gaccgttcgc tgacgctgcg ttacattcca cataatcgcg caccgctgga tcgggggcgc
    26041 aaagaagtac tgaagcatgt gcatcgcctg tggggatttg atgtgatgct ggaacagcaa
    26101 aacgaagacg gcagcgtcga gttgctggaa cgttgcccgc caagaatggg aaatctgtaa
    26161 aaacaaccaa aaacccctcg tttgaggggt ttgcttttta aacggaaggg attatcgccc
    26221 ctgaatggct aaatcacccg gcagattttt ctgcatccgg tgccaaatct cgccgctctc
    26281 atgcccatag cgacgcactg tttcgtatac ctgatcgtgt gcgccttcac tgcacaacgc
    26341 cgacagtttg tggtagaaac ccagcgccag actgcgcgct tccggattgg cgaaatagtg
    26401 acgaccaatg cgcgtataca gccctttcat cccgttaagg atcagaccgt aaatcgggtt
    26461 gccggaagca aacgccagac cgcggaatat gttgtaatcc agctcggcaa aggcatcggc
    26521 gtgatcggcc acttcattag cggtagccag cacttcctgc gctttatcgg gatgctgacg
    26581 aaacgcggtg cgaataaaaa tagtggaaat attggtacgc accgacagca aattatcaat
    26641 aagctgcggc acactttcgt gatccagtcg cgccagtgtt tcaaggatat ttaaaccgga
    26701 agtttcccag aaattattca ccttcgtcgg cttgccatgt tgaatggtca accagccatc
    26761 tcgtgccaga cgctgtaaca cttcacgtaa cgtagtacgc gttacgccaa ttaattctga
    26821 aagttcacgt tctgcgggca aaatagtccc gggagggaag cggttattcc agatactttc
    26881 aataatgtac tcttccgcga aacccgccgg gctttgcgcc ttaatgacca tagtgagatt
    26941 tccataacac agcaaaacaa agttggactc atcataccag agggctatct acgctgatag
    27001 cacacaaaaa gaagaaaaaa gggatcaagg cttcattttc tacatctctt ttctccagac
    27061 catcaacact tgcctcgatc ccctcctgac cgttaagctt tgcgttctaa gataaaaaca
    27121 tcattgatta tttctaaggt aagggaaacc atcatggaga tctcctgggg ccgtgcgcta
    27181 tggcgcaatt ttttgggcca gtcccccgac tggtacaaac tcgccctcat tattttctta
    27241 attcttaatc cgttaatttt catcatcagc ccctttgttg ccggttggct gctggtggcg
    27301 gaatttattt tcactctggc gatggccctc aaatgctatc cgctgctccc cggtggtctg
    27361 ttggctatcg aagcggtatt catcggcatg accagcgcgg aacatgttcg tgaagaggtg
    27421 gcggcgaatc ttgaagtctt gctgttactg atgtttatgg tggcgggtat ctattttatg
    27481 aaacagctgt tgctgttcat atttacccgt ttgctgctaa gcattcgctc caaaatgctg
    27541 ctgtcgctct ctttttgcat ggcggcggcg ttcctctccg cgttcctcga tgccttaacc
    27601 gtcgtggcgg tggtgatcag cgtcgcagtc ggtttttatg gtatttatca tcgtgttgcc
    27661 tcttcccgta ctgaagatac cgacctgcaa gacgatagtc atatcgacaa gcattacaaa
    27721 gtggttctgg aacagttccg tggctttttg cgcagcctga tgatgcatgc cggtgttggc
    27781 accgcattag gcggcgtgat gaccatggtg ggcgaaccac agaacttgat catcgctaaa
    27841 gcagctggct ggcattttgg cgatttcttc ctgcgcatgt cgccagtgac cgttccggtt
    27901 ctgatttgtg gcctgttgac ctgcctgctg gtggagaagc tgcgttgttt tggctacggc
    27961 gaaacgctgc cggagaaagt ccgcgaagtg ctgcaacagt ttgacgatca aagtcgccac
    28021 cagcgtaccc gtcaggataa aattcgtctg attgtccagg cgattatcgg cgtctggctg
    28081 gtcaccgcgc tggcgttgca tctggcggag gttggcctga ttggtttgtc ggtcattatt
    28141 ctggcgacat cattgactgg tgtcactgat gaacatgcta tcggtaaagc cttcaccgaa
    28201 tctctgccat tcaccgcact gttgactgtc tttttctcgg tcgtcgcggt aattattgat
    28261 cagcaactgt tctcaccaat cattcatttt gtcctacagg catcggaaca cgcccagctg
    28321 tcgttgttct atatttttaa cggcctgctg tcatccattt cggataatgt cttcgtgggg
    28381 acgatttata tcaacgaagc gaaagcggca atggaaagtg gcgctatcac gttgaagcaa
    28441 tacgagctgc tggcggtcgc cattaatacc ggtaccaatc tgccctctgt cgctacaccg
    28501 aacggtcagg ctgcgttcct gttcctgctg acctctgcac tcgcgccatt gattcgcctc
    28561 tcttatggcc gcatggtgtg gatggccctg ccttacaccc tcgtactgac actcgtcgga
    28621 ctgctctgcg tcgagtttac gcttgcccct gtaaccgaat ggtttatgca aatgggctgg
    28681 atagcaacgc tttgataaca acttaccggg catataaatg cccggtttgc cttttcgccc
    28741 gataattgtc caattgcgtc ctatttttgc tgcctcctgg tggcgcagcg aatgaattgg
    28801 tttaaactgc gcactctatg catattgcag ggaaatgatt atgttgcgat ttttgaacca
    28861 atgttcacaa ggccggggcg cgtggctgtt gatggcgttt actgctctgg cactggaact
    28921 gacggcgctg tggttccagc atgtgatgtt actgaaacct tgcgtgctct gtatttatga
    28981 acgctgcgca ttattcggcg ttctgggtgc tgcgctgatt ggcgcgatcg ccccaaaaac
    29041 gccactgcgt tatgtagcga tggttatctg gttgtatagt gcgttccgcg gtgtgcagtt
    29101 aacttacgag cacaccatgc ttcagctcta tccttcgccg tttgccacct gtgattttat
    29161 ggttcgtttc ccggaatggc tgccgctgga taaatgggtg ccgcaagtgt ttgtcgcctc
    29221 tggcgattgt gccgagcgtc agtgggattt tttaggtctg gaaatgccgc agtggttgct
    29281 cggtattttt atcgcttacc tgattgtcgc ggtgctggtg gtgatttccc agccgtttaa
    29341 agcgaaaaaa cgtgacctgt tcggtcgcta atccattcag cgctcctgcg ggagcgcttt
    29401 tttcctgccg ctatgtttat ttgacccgca gtaaatcaga acttcgcgtt gtataacgtg
    29461 gtgaaagcat ggcacgcttc atctgccatt gttgctggat cccctgcccg acaaaataga
    29521 gtgttcctct gccctcttta gcatttagcg tatccattac cgccatcaat tgctcactcc
    29581 cggggcgcgg tgcgttgtca tcgaataaat tgagctgcgc gactccctga ctgaagaaat
    29641 cccccagcat cacgcccgct ttttgataac gatggcccgc ttgccagatg gcatccagag
    29701 atcgcgtagc ggcgttaatg atatccctgc tgtcctgagt gggcgtcagc agttttaccg
    29761 acgcgctatt gccgtaataa ggttcattga gcgcaaatgg tgacgtctta ataaacgtgg
    29821 agataaaccg acaatattga tgctcgctgc gaagtttttc cgccgcccgg gcagcgtaac
    29881 tacaaatggc ctgccgcatc gacgtataat ccgtgatgcg ttcaccaaac gaacgggaac
    29941 agataatttc ctgcttcgtc ggtgcaaact cttccagttg caaacagggt tcgccgcgca
    30001 gttcacgcac cgttctttcg agcacgacat taaaatgttt acggataaac cggatatctg
    30061 tatccgccaa atcgagaacg gttttgatcc ccatcgcatc cagttttttg ctgatccgcc
    30121 gtccaatccc ccagacttca tccacgggga gagcagacat taatttacgc tggcgttcca
    30181 gatttgataa atccaccacc ccacccgtct gccgctgcca tttttttgcc gcatgattgg
    30241 caagcttagc cagcgttttg gtctgggcga tccccacacc aacagtaaga tgggttcgtt
    30301 gtagcaccgt tgcgcgaatt tctctgccaa aatcagtcag atcgcgacaa ttacgcacac
    30361 cggtcagatc gcagaatgcc tcatcaatac tgtaaatctc gacgcggggc gatagttctt
    30421 ccagcgtcga catcacccga ttgctcatgt ctgcgtaaag ctcataattg ctgctaaagc
    30481 aaaccacgcc acagcgacga aacagatctt tttgtttgaa ccagggatcg cccattttaa
    30541 cacccagcgc ctttgcctca gcgtttcggg cgataacgca accgtcatta ttcgatagca
    30601 caaccactgg tttaccccat aaatcagggc gaaacaccgt ctcacagctg gcataaaacg
    30661 cgtttacatc acagagggca aacatcagcg catcgcctta acgacgtgga tcaccacacc
    30721 aaagacatcc agcgtatctt cactactgat ggtaatgggc gagtacgcgc tgttcatggg
    30781 aataagctgt accgtcgggc gtagttgcaa ttttttcacc gtaaactcgc cgtcaacagc
    30841 agcgatgaca atatcaccat ggctggcggt aatagcgcta tcgacaatca gtaaatcacc
    30901 gtcactaatt ccaccatcaa tcatagaatc accacttgct ttgacgaagt aagtcgcgct
    30961 gggatgctgg atcaacagtt gattcagatc gatgcgctgt tcaatgtaat ctgcggccgg
    31021 tgaaggaaag ccacactgaa caagatcgct aaatagcgga aaagtcacaa tttcgcggag
    31081 atccgcaggc ttgataaaca acataataat ctgcctgaag ttatactgtt tttatataca
    31141 gtagtctgtt cttaccagca gatcaatact gattcaggct atcaatattt gtcgctgcat
    31201 agactgctga tttttcgttc tcttatcctg tgctcacgcg ccttctggcg acgacgctca
    31261 tccagcagaa atgaaaaata tcacccggct aaaaaataga atagaagcat cagccataat
    31321 gacattaaac attgtttgat atttatcata ttaatagaaa taaagacatt gacgcatccc
    31381 gcccggctaa ctatgaatta gatgaagtaa aattctttaa tagttgtaaa acaggagttt
    31441 cattacaatt tatatattta aagaggcgaa tgattatgac tgaaatcgtt gcagataaaa
    31501 cggtagaggt agttaaaaac gcaatcgaaa ccgcagatgg agcattagat ctttataata
    31561 aatatctcga tcaggtcatc ccctggcaga cctttgatga aaccataaaa gagttaagtc
    31621 gctttaaaca ggagtattca caggcagcct ccgttttagt tggcgatatt aaaaccttac
    31681 ttatggatag ccaggataag tattttgaag caacccaaac agtgtatgaa tggtgtggtg
    31741 ttgcgacgca attgctcgca gcgtatattt tgctatttga tgagtacaat gagaagaaag
    31801 catccgccca gaaagacatt ctcattaagg tactggatga cggtatcacg aagctgaatg
    31861 aagcgcaaaa atccctgctg gtaagctcac aaagtttcaa caacgcttcc gggaaactgc
    31921 tggcgttaga tagccagtta accaatgatt tttcagaaaa aagcagctat ttccagtcac
    31981 aggtagataa aatcaggaag gaagcgtatg ccggtgccgc agccggtgtc gtcgccggtc
    32041 catttggttt aatcatttcc tattctattg ctgcgggcgt agttgaaggg aaactgattc
    32101 cagaattgaa gaacaagtta aaatctgtgc agagtttctt taccaccctg tctaacacgg
    32161 ttaaacaagc gaataaagat atcgatgccg ccaaattgaa attaaccacc gaaatagccg
    32221 ccatcgggga gataaaaacg gaaactgaaa caaccagatt ctacgttgat tatgatgatt
    32281 taatgctttc tttgctaaaa gaagcggcca aaaaaatgat taacacctgt aatgagtatc
    32341 agaaaagaca cggtaagaag acactctttg aggtacctga agtctgatca gcgattattc
    32401 tctccatgta ctcaaggtat aaagtttatc acatttaaaa atacagacgt tttttaaaga
    32461 ttgagagtta cctgttgata ataaggtatc gggtaactct cattatgaca gagcgctttc
    32521 aaaaacaggg ctacgaaatg gcgagcatcc agacgtatat taagaaagcc cccatcaaca
    32581 tctattaaat ttatcactgc gcccagtcag gtttatttaa gatatgatcc tgccagtcaa
    32641 tcacttctga ttctttcact gcgatatgac gcacagagat acgttcgcca tgcattgccg
    32701 ctttcgaacc agtaagcagc ggatgccacg caggtaaatc tttaccttcc gccagcaagc
    32761 gataagcgca ggtcattggc agccattcga atgttggcag attttcacgg gttaatttaa
    32821 tgcagtcagg ttcaaactcg aaacgacgtt cgtagttccg acattgacag gttttaatat
    32881 tgagctggcg acaggcgacg ttagtgaagt agatttcgtc ggtgtcttca tccatcagtt
    32941 tatgcaggca acactgaccg caaccatcac acaacgactc ccattccgca tcgctcattt
    33001 cgtccagggt tttactttgc cagaaaggta catcgctcat caggtgttcc gccattacgt
    33061 taaaacgcac cttataacca gtctggcaca gcgatgcaag ttttgccgtc gctttcaggc
    33121 ggcaaaaagt attacaaaac gcgagttgtc aaagaatgcc catcaaaagt gactgtcagc
    33181 tcatcaccgc tttgcaacgg gccgacgcca tcaggcgtgc ctgtcagcac aacgtcaccg
    33241 gccttgaggg taaagaactt gctcatataa gcgatcagcg gaacgatttt atggatcatg
    33301 tccgcagtcg taccttgctg gcgttgttcg ccgtttacgc tcaggcccag cgttgtattt
    33361 tgcgggtcgc cggtaaattc cgccgtggga ataaacccgg aaagcggaca agagttgtca
    33421 aacgctttag ccttttccca cggctgcccg gctttcttca tttttccctg aacatcacgc
    33481 aatgtcagat cgagcgccac gccataaccg gcaatggctt tgcggacatg ctcttccgta
    33541 gcctgacgca gcgtcgcgcc aatcaatacc gccagttcga cttcatgatg aactgaaccg
    33601 aaatcggatg ggatcgccaa tggctgccgc agatcgcaca gtgccgtttc tggtttaata
    33661 aacagcactg gctcttcggg cactgcgctg cccatctctt taatatggtt ggcatagtta
    33721 ctgccaacac agactacttt actcaccgga taatccagca gcgcaccttg ccagttgtga
    33781 tgttgataca taacgttccc ctcaccttat cgtggatatg aaaacccgcg ccgacaaaga
    33841 taatgccacc gccggatgtc ggttatttgt tcgtgtcgtc tgttttctgc cccatgacgg
    33901 aaagatgttg cttcagcaaa tcttcgggtg gtggcggtaa ctgcaaatag taaccttgct
    33961 cggttaatgc ctgtttaacc ttttcaatat cggcattgac cagtttcttc cgcccatcca
    34021 gcggcagaat catcgctaac tgaggctgac caaaaccttt catcagttcc tcaggaacac
    34081 gcgaaaaatc gtcttttttt tcgacatata aataggtctg gtcacgcttg ctgcttcgat
    34141 aaatcacaca aaacatactt ttactcttta agatgccagg ttttggcata agctaacatc
    34201 aatgaaaccc gcgccacaag ccagccagct gtagatttct gcggtttgtt cagtccatgc
    34261 gcccttaata agtgatcccc cggcaaaaat gccgcgccgg gatttaaccg aacgcaggaa
    34321 agccactgga attctcctgt gatgaattgt tatattataa cagttcatcg tactcattct
    34381 gaacaggaga ctaccaatga aaattaaggg catcagtaag gctgtattgt tgcttgcact
    34441 gctaacctcc acgagctttg ctgcgggtaa gaatgtcaat gttgagttca gaaaaggcca
    34501 tagcagcgct cagtactccg gcgaaataaa gggatacgat tacgatacat ataccttcta
    34561 tgccaaaaaa ggtcagaaag tgcatgtgag tatctctaat gaaggcgctg atacttacct
    34621 cttcgggcca ggaatcgatg attctgttga tttatccaga tattccccag aactcgatag
    34681 tcacggacaa tacgcactcc ctgcttctgg caaatatgag ctgcgagtgc tgcaaacccg
    34741 aaacgacgcc cgtaaaaaca aaactaaaaa atataacgtc gatattcaaa ttaagtaaat
    34801 gtcaaccgac ggggactctc cccgtcataa acgttaacgc cccactcctc tctgtcgctc
    34861 aagaggttaa tgacgaatag aacatcatgt aaacaagaca tcactcacga cacataaata
    34921 acatctttgt ggtggtttga ttgatttttc cactccgctt accatctaca ccaaaataac
    34981 gatcatcacg acataatttt tctttaacat cgcaaaatac accgttagag aatgtaaatt
    35041 cgctgggatc gtaaccttgt actgattgta agttttcagc ggctttttcg ccgagatatt
    35101 tccttgttaa ctctggggaa atgccatctg agttaacaca aatatacgag tcgcaaacaa
    35161 cgccgcacgc cggagattga agtccgccag cgtcatttcc agacgccatt gatgagaaca
    35221 tcatccccac acctgacaat ccgatataaa taatacgcat catattcata gcacatcctg
    35281 ataatccaac cgtacaacac ttatgctcat ttcgtcatca atccgtaatc aaaaccgctg
    35341 acctggacga gttacgatga cctgacagaa gtatcagacg tcttctgcgg tttctatgat
    35401 agagcaattc tgtggcggat attaagataa cgggtatctg ttctttaatg atgccgcaaa
    35461 aaatggaaag ttaagaaaac ctggcgtggt gaaaaaatac acttgcctca atactggata
    35521 tttaaacagg tctggagatg ctgtcacgat tagggtgtgg aaaaaggaag cgtaaataag
    35581 aacaatcaaa agtacgacgg caatgggttg attgacaagg gtatttttta agctatgtat
    35641 cagcgccatt tatcacagaa tagactttta ctctgaataa atgggagggt gacttgcctc
    35701 aatataatcc agactataac atgccttata gtcttcggaa catcatcgcg cgctggcgat
    35761 gattaatagc taattgagta aggccaggat gtcaaacacg ccaatcgagc ttaaaggcag
    35821 tagcttcact ttatctgtgg ttcatctgca tgaggcagaa cctaaggtta tccatcaggc
    35881 gctggaagac aaaatcgctc aggcccccgc atttttaaaa catgcccccg ttgtactcaa
    35941 cgtcagtgca ctggaagacc cggtaaactg gtcagcgatg cataaggcgg tttcggcaac
    36001 cggtttgcgg gttattggcg taagtggctg caaagatgcg caacttaaag ccgaaattga
    36061 aaaaatgggg ctgcctatcc tgacggaagg aaaggaaaaa gcgccgcgtc cagctcccgc
    36121 accgcaggct ccagcgcaaa atacaacgcc ggtcacaaaa acgcgtttaa tagatacccc
    36181 ggtgcgttcc ggtcagcgta tttatgctcc acaatgtgat ctgattgtta caagccacgt
    36241 tagcgctggg gccgaattga ttgccgatgg taacattcat gtctatggca tgatgcgcgg
    36301 tcgtgcgctg gcaggggcaa gtggtaaccg ggaaacgcaa atattttgta cgaacctgat
    36361 ggcggaactg gtgtccatcg caggtgaata ctggctgagt gatcaaatcc cagcagaatt
    36421 ttatggcaaa gcggcacgac tgcagttagt tgaaaacgct ttgaccgttc aaccgttaaa
    36481 ttgatccctt tttaacaagg aatttctatg gcacgcatta ttgttgttac ttcgggcaaa
    36541 gggggtgttg gtaagacaac ctccagcgcg gccatcgcca ctggtttggc ccagaaggga
    36601 aagaaaactg tcgtgataga ttttgatatc ggcctgcgta atctcgacct gattatgggt
    36661 tgtgaacgtc gggtcgttta cgatttcgtc aacgtcattc agggcgatgc aacgctaaat
    36721 caggcgttaa ttaaagataa gcgtactgaa aatctctata ttcttccggc atcgcaaact
    36781 cgcgataaag atgccctcac ccgtgaaggg gtcgccaaag ttcttgatga tctgaaagcg
    36841 atggactttg aatttattgt ttgcgactcc ccggcaggga ttgagaccgg tgcgctaatg
    36901 gcactctatt ttgcagacga agccattatt accaccaacc cggaagtctc ctcagtacgc
    36961 gactctgacc gtattttagg cattctggcg tcgaaatcac gccgcgcaga aaatggcgaa
    37021 gagcctatta aagagcacct gctgttaacg cgctataacc caggccgcgt aagcagaggt
    37081 gacatgctga gcatggaaga tgtgctggag atcctgcgca tcaaactcgt cggtgtgatc
    37141 cctgaggatc aatcagtatt gcgcgcctct aaccagggtg aaccggtcat cctcgacatt
    37201 aacgccgatg cgggtaaagc ctacgcagat accgtagaac gtctgttggg agaagaacgt
    37261 cctttccgct tcattgaaga agagaagaaa ggcttcctca aacgcttgtt cggaggataa
    37321 gttatggcat tactcgattt ctttctctcg cggaagaaaa acacggccaa cattgcaaaa
    37381 gaacggctgc agattattgt tgctgaacgc cgtcgcagcg atgcagaacc gcattatctg
    37441 ccgcagttgc gtaaagatat tcttgaggtc atttgtaaat acgtacaaat tgatcctgag
    37501 atggtaaccg tacagcttga gcaaaaagat ggcgatattt ctattcttga gctgaacgtg
    37561 accttaccgg aagcagaaga gctgaaataa gcccgctgta aaagcgcatt tatcttcaag
    37621 gcagagtcat ctctgccttg agtttttcat ccccctcatc cacgtttgat aagagcggcg
    37681 agtattcttg ctgatgctac tcattgcttc ccccccttta caccttaatg ccgttccccc
    37741 cacacagaac aaattgttta tacctggctg agtaaataac cttattgtta gtatgggtat
    37801 gctgggagat gataaccccg caatttcatt attcattgtt ctcccatagg atgaggtttc
    37861 ccgccgtaac tggcgggctt tttttgccgc agaattttct cttttaacat cctgtaaacg
    37921 gaaactgcgc cgaagcgcag tttaatcgtt gatggtcaga acgaccagtt cgcaccagcc
    37981 accgcgttcc acggggattc cacaccggca ccatgactat accccacccc gagatgcccg
    38041 cttaacgaac tgctgaatga ggctttaata cctgcctggt atattccacg tctgtccgac
    38101 aaatcattga caaaattacc gtcattattc actttcaccc ggttatcatc gacaaattct
    38161 ttgcgcacag ccgccttcaa ccacggctca acttccatac cgttacccag acgcatgttg
    38221 taactcagcg ttgcgcccag ttcacgatat atactgcggg tatcgactga tttcgacccc
    38281 atgccattgg ataaatgata gtagcgtcta agtgacctta gctctgctgc aacatcagcc
    38341 cgcaggcacc agaccagggg attgatcctg aagagacagc gcaggtgtat tgtgttcacc
    38401 gctcatcaaa gacatcatga tgaaataatg atatcccgca taagaaagag gcatttttta
    38461 aacgcagtgc gctgaagtgt agttggataa aaaatcactc ttttctgata atactgttgt
    38521 acgcttattt ttcgacaatg aggccgtcgg caaaataaaa tgactaatgt aatcattgct
    38581 gatgaatatt ttctgctcac ataaaaatca cacaataata ttcataaatc agattatctt
    38641 acctttacaa cattgtatta acactcaatg acacttcttg aataaaaata ttgtcaatca
    38701 atgagttatt tctcatttga gattattctt attcccgtaa aaaacataat tcctatcatc
    38761 acagtcacgc tcattttgaa ttatctgaat aatagcgagc gttctttagt taagccgatc
    38821 ttaattgaag acgaaattat tgtgtgtgca acttacttaa taccggacat ctaagttgaa
    38881 gaaaaaaata cttgccttcg ggcttatctc agcattgttc tgctccacgc cagcgatggc
    38941 ggatatgaat cgcaccacga aaggtgcatt gctaggcgca ggcgttggtt tacttactgg
    39001 caatggtgtt aatggcgtac tgaaaggtgc agctgttggc gctggtgttg gtgcagtaac
    39061 agaaaaaggc cgcgacggta aaaatgcgcg taaaggtgca aaagtgggtg ccgccgttgg
    39121 tgctgtcact ggcgttctga ccggcaatgg cctcgaaggg gcgattaaag gtgccgtgat
    39181 tggcggtacg ggtggtgcaa ttctgggtaa aatgaaataa ggaatgatga tgaaaaaatt
    39241 tgctttactg gcgggtctgt ttgttttcgc accaatgacc tgggcgcagg actataatat
    39301 taaaaacggt ttgccgtcag aaacctatat tacttgcgca gaagccaacg aaatggcaaa
    39361 aactgacagc gcacaggttg cagaaattgt tgcggtaatg ggtaatgcca gcgttgccag
    39421 ccgtgattta aaaattgagc aatctccgga actgagcgcc aaagtggtag aaaaactgaa
    39481 tcaggtttgc gctaaagacc cgcaaatgct gttgatcacg gcaattgatg acaccatgcg
    39541 tgctatcggc aaaaaataat atttaatatg ttaccgcgtc gatgaaatcg acgcggtttt
    39601 ttagctaacg gggatcagaa cttatatttc aggcccacca tcactgcggt gtcattgtag
    39661 ccattatcac ccagctgcac gcccacatta ccccagacac tggccgccgg attcagattg
    39721 ccatttacgc caagtttgat ttcccccaga ttacgcgccc cgtcttgttc aactttcaca
    39781 ccgttcattg agacagcaaa atctttactg ttatggatcc agttcatttc aacaaaaggt
    39841 tcaaagtcgt caccgtgagg accgctgttt ttctcctgag tacgaataaa ggtgcggaaa
    39901 ccaagtcggg tctggaagtt gttatttgcg tcattctcaa tacgtgagcc attggcttcc
    39961 gtgtgcgcat tatgatcgac gcccatccag atagcctgtg cctgtggctg gaagatccac
    40021 gtatatttcg ccgcttccag accaaaggat ttattcaggg caaagccgta acccgcttcc
    40081 agcgagacgg ttgcgccttt cgcgctatag gattcatagg ctaactcatc ccctttcacc
    40141 gagtttttaa accagctata ttgcgcccag gcgtcaatgt atgcgccttt tttactgatg
    40201 tcatcggcaa accaggtggc atacagccct gcgctatagc ctctgacact ccctttcgaa
    40261 cgataatccg acacgctgga atgagttgag ttgtagtcgc gggcataacc agccatcact
    40321 cccaaacgcc aactgtcact gtcggtaaaa ccaccggtta acagatccgc ccctaactgc
    40381 gagacgtagc gatgcgaggt cgttctcaac tgtccgttgc tgtcacgcca ggcattatgc
    40441 ccgccaattt gacgtagcca aagtcggctt gaacgctcct gttcagttac aggatcgatg
    40501 tagcgcgttt cacctgcacg atcgttcaga cgcataacaa aaagagtgtt agcggctgcc
    40561 aggttggcga cgtaacttcc agcttcgggg cgcagaacgg gggtaggcgc aacagtaggc
    40621 gctgaacttc ctccggagtt tgtttcaccg ccgctcgttg cctggaagtt agtcagatac
    40681 cagtttttat tggtcgcttc ggtattacct cgggttaatg aatattcgta ggcaccggcg
    40741 aaaatcctcg aatccttaat aaattcccca tttgattccc cctcaacgct gataatctct
    40801 atcccattta acgtgtaagc cccgctgccc ccagcattgg taacttttac tcgggttgtt
    40861 ccggaggtat ttccattaat aacaacttta tcagtagctg aattatcatc acccaattca
    40921 gttctgagat gcaatacgcc attattacca acgtaatttt cagttattgt taaccttgtt
    40981 ggttcgaaat cctttccatc tgcccgggaa atatagaccg tactattgtc aaccgtgagc
    41041 ttgctcaccg ttgagtcagt tttaatatcc caggtactat tatctgaaag cgacagatag
    41101 gtatgagtgc tatcatctgt tgaaagattg gctgaacccg ttatttttga attagatgca
    41161 tcgatggcca aatgaccttt aatattatta ataaaaacat ctgcagccga tgatacctca
    41221 ctatccgtaa tggtcacgtt actcgtctca tttttattgt agaggatttc atttgctgac
    41281 cgtagtgagc taccagataa aatatctacc gttgcttcct gaccatttat ggaagactcc
    41341 agcacaaatc cagccccctg atgcgcgact gcagatgtat ttttcagcgt caccttgccg
    41401 ccattataaa ttttagcaat cgcggtgtca ggacccgttg tatgaatttc tccctggtta
    41461 aatgaaacag tctcctggcg agcagcgatg gcatgagcat tgtccccatg cgtggtaata
    41521 tcaacatcgg ttaatgtaac gctggcattg gtataatcaa gcttgctacc cgccttgacg
    41581 acagtgccat tagcgtaagc ggcataactt tctgttccgt gggttgttat ctcccctttt
    41641 gccatatcca gttttgcttt ggtgttattt tcattacttc ctgtatcggc agtactttct
    41701 tcatcaagag aagatacaca cgcacgcgcg cttccgggag atgcacaagc aagaacgccg
    41761 actgcgtgat tacccgcagt aacaataaaa gtaatacctt cgtcagataa atgggggtta
    41821 accgaaccgt cagtgttgac tcttattatg gtatcagtat tcaggtttcc attcgtttga
    41881 cttagcaaac caattgagta atcccccgtt gtgacaatcg tattattacc ctgcaaaata
    41941 actgcaccgc catattcact tacgactgcg ctagctgtat atactgtgct tagaggacta
    42001 ttgccagaag gatataaacc acccgttgtt acaatgacgc cattgttaat ggttaaattg
    42061 ctaccctttc ctgcaacaga tacaccgtaa cttccattac ccgttgttat aactagcgca
    42121 ttatcaatat cttttacttc tccatctttt atttcaacaa catgtttagg ttcatcgtgc
    42181 tgaataaact atccagcata tgcattaccc accgccaaag caataagtca taaactaaac
    42241 ccggggagtt ttttcagttt catagattaa ccatccattc attggattaa caaacattcc
    42301 tggtcaaata acctatgagt tcagattacc aaaacggagg gtaaagacaa aaacaaaagc
    42361 acaagaaatt taaatagata aacagcgaca atacataaat gataaataag tcagcattat
    42421 catttttcac cttattttca tgacattgat cactttggag tgacgatttt gtttaacaaa
    42481 taactcttcg acatcaaaat tattaatagt tgccatggga attatttcga tgatatataa
    42541 aaacaactgt gataacacca gggttgacaa ctatttgcgc aataatacct ttccttcaat
    42601 gatccaggcg ttcactgcca gcaacccatt cagccgcata ctgacagtga gaaactgaaa
    42661 gtttagtgct gatccctgtg gctgacgagt ctttccctta atcgattaac cagattgatc
    42721 gccagccaaa caagggcatt aagcaaattt atcgtcacaa gcacttctcc cagcccggta
    42781 ctgggttttg caataaggat gaccaggaga gtgatcagca taaatgcaat ggaaaagatg
    42841 atatagagag tgaaataatc cagattatta ctattgttca tgctactaat ggcaatcctg
    42901 tcaaaacttt caaacaatta tagcaaacaa aataatgaac aatagtaaca agaggcaacg
    42961 agctaattag ctgtctataa ttacaccgca ccatggcctt actgatcgat tttcactcaa
    43021 ccacaacctt caccttcggt ttagaaagga taattttgac caggtcgatg tatgtaacag
    43081 gtttatagaa ataataaccc tgctgaaatg tgatattatt ttggttcaga taatcaagtt
    43141 gttctttcgt ttcgacacct tcagcgacga tactgatcga aagtttacgc gccagatcca
    43201 atacacaatc cagaattcgg gttgattctg ggtctgcgtt gacgcggcca acgaaactgt
    43261 gatcaatttt gatataatca atatgcaggt catgcagata agaaagccct gagtagccag
    43321 taccgaaatc atccagcgcg atgacaaaac cattttcatg cagaatgttc aaccgctgaa
    43381 ccagactttc atcaacattt aatggctcac gctcggtgac ttccagaacg aggtttaaat
    43441 cgcggcgggt aaaactgtca cggtaattta agcactcgtc gacaaacgtc ggcgaaataa
    43501 tatgcgaggc gctaaaatta attccaatat gaaaaccctc cggcagttta ctcgagatag
    43561 cgttcatctg tctggcaacc tgattcatca ggctttgcgt aagcggaacg attaatccgg
    43621 atttttcagc aagtggaata aatgccgcgg gtgatatata tccaccgtga ggttgtttcc
    43681 agcgggctaa cacctcaact ccccgcaatg tcccttcccg accatttacc acaggttggt
    43741 aaaaagggac gatctcccca ttatttatag cccgtcgcag gatctcttca ggcgttgcgc
    43801 ttttattgaa atacctatca agcagcaaag cagcggcgca ggcgattaac agaataaata
    43861 tcaatatccc aaagccttta tcgataagtc tgtagaagct aaagagtggt ggcgggttaa
    43921 agataatagt gaaatgatat tttgtggagt gaaccttctc ggtataggga taatgtccat
    43981 taagcgtcat cacatcaccc gtaggtccaa taatgtcatc cgccacgcgt aatacatacc
    44041 ttaccccttt caagggtaca ttaagcgccc cgcgaatatg ctgatcactt atcgtaacca
    44101 aaatgcgcgt atctgcaaat tggctctgat agagcaggat aggtaatcta ttaacggtgt
    44161 cgattgccgg agccaacagt aaattactgt ccgggacaac aggaatacga gacagcagga
    44221 cccgattccc cggtaaggat gtacaccaga ccgttccctg tttgagaatg atgattgtgc
    44281 gcaggtgagg tttcagagct gcttcagtgc caagctgata ttgctcctcg aggtcgcatt
    44341 ccttcccggc aatgttaacc gctgtttgag tcgcctgtga tgcttcttca agtatatgat
    44401 tgatattgtt ggcggcatat ctcgctcccg ccaggtactc tgcttttgcg gagtaccaga
    44461 gctggatgtt caaaatagcg acaccggtta taaacaagca tatcgcaacg aggatgggta
    44521 tgagtgtatt gcgcattcgc ttgtcccgaa caaagggttt aatacatgaa aatgacgttc
    44581 attcgctcgc gctggcgtct acagagagca tggtagagag cataagaaat atccacgccg
    44641 aagataaaat tttctccatc ttgatctaac ccattaatta ttgagcataa tgtagatagg
    44701 ataaaataaa ttaggcggga tatcaggtgt caagaatgga gagcgagaac tctccattct
    44761 tgacacctga tattgcggac atattaagaa agcataacgc ctgaaatgct cactttgcac
    44821 cagcatggta atacagctga tgtttattct ataaccttac tcaagttcta agagatcacg
    44881 gattccctgt cattaataat gatatccgtt agtgtagtct tatgcatttc aatgtactgc
    44941 aatatttgca gatagagatc agaaagaatc acactggttt catcttttaa acgcaagcgt
    45001 aaagcctgat caataatata actatcaaca tacccatgcg tcatgaacac ctccctctcg
    45061 agatttttaa acaaagcaca ttgcaaaata aatctctctg ggattgaatt attcatgtca
    45121 gcctcgtaga aatattaacc caataaaatt atgctgtgta tagtctaaag cgacagacaa
    45181 aaataagatg aatgagtttt ctataaattt atacttaata attaaaagtc acatatcatc
    45241 cgctgtgtat cgcaacacga tttccagtgt ttttctgatc acatcagctt tgaggatatc
    45301 atttgttgtt tccagggagt gtatcagact taagataata tttttattat taacattatc
    45361 gcctgaaagc attaaattgg tgacagcctg ccctaacaca gctgactctt cttctaacaa
    45421 attacccgaa ctgcgaaagt aacttgataa cgctttatca gctattgcat tatgaatagt
    45481 agtatcttca agcatagtaa cctctcatct tacttatgaa attttaatgt attctgttta
    45541 ttttcttacc attgaaaata cttttattgt cagttatcgc tgttcttctg tttggccctc
    45601 ctgtatcact gttactaaaa tcacgaatta tgctgtcaat taaatctcgt cggaaagcat
    45661 tttcctcaac agatttcatt acgagtaatt gcttaataag agtctgcaac gaaaaattta
    45721 tcttcatgcg cagtatctgg agcaccgcct ggccagtaat ttcatatttt gtactttcat
    45781 tatcagatgt cttcataacg acttcatagc taacctgtta aataatcagg ctgttgcatt
    45841 attcaaaaag caacccaatt agtgcattat aatgtttctg ttcctcttcc cctgtcgctt
    45901 gttccagtcg acctagaagt ttggcacaaa gcgactttcg actcagatta cgtccatctt
    45961 tcaaaatctc agtcacaatt tctccgagag tttcctgctg agtaggcaag ttagcttttg
    46021 caaagtaacg agtgattgct cccgcagaat ctaaagtcac tgaattttga tgcatgctac
    46081 gcctctgtta aaaatgttaa tcaatgttaa gtgaggtaac aatagcaaac ttgtacgaaa
    46141 tatgtgtaca aaatgataaa ttaatttttt gcattta
//
LOCUS       DADXDL010000027        45352 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.027, whole genome shotgun sequence.
ACCESSION   DADXDL010000027 DADXDL010000000
VERSION     DADXDL010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 45352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45352
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.027"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(226..1083)
                     /gene="murI"
                     /locus_tag="IRB70_001830"
     CDS             complement(226..1083)
                     /gene="murI"
                     /locus_tag="IRB70_001830"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBC0631750.1"
                     /translation="MATKLQDGNTPCLAATPSEPRPTVLVFDSGVGGLSVYDEIRHLL
                     PDLHYIYAFDNVAFPYGEKSEAFIVERVVAIVTAVQKRYPLALAVVACNTASTVSLPA
                     LREKFDFPVVGVVPAIKPAARLTANGIVGLLATRGTVKRSYTHELIARFANECQIEML
                     GSAEMVELAEAKLHGEDVSLDALKRILRPWLRMKEPPDTVVLGCTHFPLLQEELLQVL
                     PEGTRLVDSGAAIARRTAWLLEHEAPDAKSADANIAFCMAMTPEAEQLLPVLQRYGFE
                     TLEKLAVLG"
     gene            complement(1028..2872)
                     /gene="btuB"
                     /locus_tag="IRB70_001831"
     CDS             complement(1028..2872)
                     /gene="btuB"
                     /locus_tag="IRB70_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent vitamin B12 receptor BtuB"
                     /protein_id="HBC0631751.1"
                     /translation="MIKKASLLTACSVTAFSAWAQDTSPDTLVVTANRFEQPRSTVLA
                     PTTVVTRQDIDRWQSTSVNDVLRRLPGVDITQNGGSGQLSSIFIRGTNASHVLVLIDG
                     VRLNLAGVSGSADLSQFPIALVQRIEYIRGPRSAVYGSDAIGGVVNIITTRDEPGTEI
                     SAGWGSNSYQNYDVSTQQQLGDKTRVTLLGDYAHTHGYDVVAYGNTGTQAQTDNDGFL
                     SKTLYGALEHNFTDAWSGFVRGYGYDNRTNYDAYYSPGSPLLDTRKLYSQSWDAGLRY
                     NGELIKSQLITSYSHSKDYNYDPHYGRYDSSATLDEMKQYTVQWANNVIVGHGSIGAG
                     VDWQKQTTTPGTGYVEDGYDQRNTGIYLTGLQQVGDFTFEGAARSDDNSQFGRHGTWQ
                     TSAGWEFIEGYRFIASYGTSYKAPNLGQLYGFYGNPNLNPEKSKQWEGAFEGLTAGVN
                     WRISGYRNDVSDLIDYDDHTLKYYNEGKARIKGVEATANFDTGPLTHTVSYDYVDARN
                     AITDVPLLRRAKQQVKYQLDWQLYDFDWGITYQYLGTRYDKDYSSYPYQTVKMGGVSL
                     WDLAVAYPVTSHLTVRGKIANLFDKDYETVYGYQTAGREYTLSGSYTF"
     regulatory      complement(2937..3127)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00174"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="cobalamin riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="adenosylcobalamin"
                     /db_xref="RFAM:RF00174"
     gene            3241..4341
                     /gene="trmA"
                     /locus_tag="IRB70_001832"
     CDS             3241..4341
                     /gene="trmA"
                     /locus_tag="IRB70_001832"
                     /EC_number="2.1.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (uridine(54)-C5)-methyltransferase TrmA"
                     /protein_id="HBC0631752.1"
                     /translation="MTPEHLPTEQYEAQLAEKVVRLQSMMAPFSDLVPEVFRSPVSHY
                     RMRAEFRIWHDGDDLYHIIFDQQTKSRIRVDSFPAASELINQLMTAMIAGVRNNPVLR
                     HKLFQIDYLTTLSNQAVVSLLYHKKLDDEWRQEAEALRDALRAQNLNVHLIGRATKTK
                     IELDQDYIDERLPVAGKEMIYRQVENSFTQPNAAMNIQMLEWALDVTKGSKGDLLELY
                     CGNGNFSLALARNFDRVLATEIAKPSVAAAQYNIAANHIDNVQIIRMAAEEFTQAMNG
                     VREFHRLQGIDLKSYQCETIFVDPPRSGLDSETEKMVQAYPRILYISCNPETLCKNLE
                     TLSQTHKVERLALFDQFPYTHHMECGVLLTAK"
     gene            complement(4381..4740)
                     /locus_tag="IRB70_001833"
     CDS             complement(4381..4740)
                     /locus_tag="IRB70_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YijD family membrane protein"
                     /protein_id="HBC0631753.1"
                     /translation="MKQANQDRGTLLLALVAGLSINGTFAALFSSIVPFSVFPIISLV
                     LTVYCLHQRYLNRTMPVGLPGLAAACFILGVLLYSTVVRAEYPDIGSNFFPAVLSVIM
                     VFWIGAKMRNRKQEVAE"
     gene            complement(4740..5390)
                     /gene="fabR"
                     /locus_tag="IRB70_001834"
     CDS             complement(4740..5390)
                     /gene="fabR"
                     /locus_tag="IRB70_001834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002460670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor FabR"
                     /protein_id="HBC0631754.1"
                     /translation="MMGVRAQQKEKTRRSLVEAAFSQLSAERSFASLSLREVAREAGI
                     APTSFYRHFRDVDELGLTMVDESGLMLRQLMRQARQRIAKGGSVIRTSVSTFMEFIGN
                     NPNAFRLLLRERSGTSAAFRAAVAREIQHFIAELADYLELENHMPRAFTEAQAEAMVT
                     IVFSAGAEALDVGVEQRRQLEERLVLQLRMISKGAYYWYRREQEKTAIIPGNVKDE"
     gene            5722..7122
                     /gene="sthA"
                     /locus_tag="IRB70_001835"
     CDS             5722..7122
                     /gene="sthA"
                     /locus_tag="IRB70_001835"
                     /EC_number="1.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418397.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Si-specific NAD(P)(+) transhydrogenase"
                     /protein_id="HBC0631755.1"
                     /translation="MPHSYDYDAIVIGSGPGGEGAAMGLVKQGARVAVIERYQNVGGG
                     CTHWGTIPSKALRHAVSRIIEFNQNPLYSDHSRLLRSSFADILNHADNVINQQTRMRQ
                     GFYERNHCEILQGNARFVDEHTLALDCPDGSVETLTAEKFVIACGSRPYHPTDVDFTH
                     PRIYDSDSILSMHHEPRHVLIYGAGVIGCEYASIFRGMDVKVDLINTRDRLLAFLDQE
                     MSDSLSYHFWNSGVVIRHNEEYEKIEGCDDGVIMHLKSGKKLKADCLLYANGRTGNTD
                     SLALQNIGLETDSRGQLKVNSMYQTAQPHVYAVGDVIGYPSLASAAYDQGRIAAQALV
                     KGEANAHLIEDIPTGIYTIPEISSVGKTEQQLTAMKVPYEVGRAQFKHLARAQIVGMN
                     VGTLKILFHRETKEILGIHCFGERAAEIIHIGQAIMEQKGGGNTIEYFVNTTFNYPTM
                     AEAYRVAALNGLNRLF"
     gene            complement(7105..8022)
                     /gene="oxyR"
                     /locus_tag="IRB70_001836"
     CDS             complement(7105..8022)
                     /gene="oxyR"
                     /locus_tag="IRB70_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016831323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator OxyR"
                     /protein_id="HBC0631756.1"
                     /translation="MNIRDLEYLVALAEHRHFRRAADSCHVSQPTLSGQIRKLEDELG
                     VMLLERTSRKVLFTQAGMLLVDQARTVLREVKVLKEMASQQGETMSGPLHIGLIPTVG
                     PYLLPHIIPMLHQTFPKLEMYLHEAQTHQLLAQLDSGKLDCVILALVKESEAFIEVPL
                     FDEPMLLAIYEDHPWANRECVPMADLAGEKLLMLEDGHCLRDQAMGFCFEAGADEDTH
                     FRATSLETLRNMVAAGSGITLLPALAVPPERKRDGVVYLPCIKPEPRRTIGLVYRPGS
                     PLRSRYEQLAEAIRARMDGHFDKVLKQAV"
     gene            complement(8273..9280)
                     /locus_tag="IRB70_001837"
     CDS             complement(8273..9280)
                     /locus_tag="IRB70_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000382182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0631757.1"
                     /translation="MDVDVSTSVAGNKPQRIRRIQTVTLVLLFMAGIVNFLDRSSLSV
                     AGEAIRGELGLSATEFGVLLSAFSLSYGFSQLPSGILLDRFGPRIVLGAGLIFWSLMQ
                     ALTGMVNSFSHFILMRIGLGIGEAPFMPAGVKSITDWYAQKERGTALGIFNSSTVIGQ
                     AIAPPALVLMQLAWGWRAMFVIIGVAGIPFLAAAVGMWVNGIVVDRLAKKGYDLAKTR
                     KTAIVCGLMMSALGTLLVVQSSSPAQAVAFISMALFCVHFAGTSAWGLVQVMVSETKV
                     ASIAGIQNFGSFVFASFAPIVTGWVVDTTHSFNLALVIAACVTFTGALCYFFIVKDRI
                     E"
     gene            complement(9347..10561)
                     /locus_tag="IRB70_001838"
     CDS             complement(9347..10561)
                     /locus_tag="IRB70_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-galactonate dehydratase family protein"
                     /protein_id="HBC0631758.1"
                     /translation="MKIIAADVFVTCPGRNFVTLKITTASGLCGLGDATLNGRELSVA
                     SYLKDHLCPQLIGRDASRIEDIWQFFYKGAYWRRGPVTMSAISAIDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGRTIDEVLEDYAKHQQMGFKAIRVQCGVPGMQTTYG
                     LAKGKGLAYEPATKGLWPEEQLWSSEKYLDFTPKLFEAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRLFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTITHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCHAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHSWRFDEGYMHPGDEPGLGISFDEKLAAKYPYDPAYLP
                     VARLEDGTLWNW"
     gene            complement(11047..12420)
                     /gene="argH"
                     /locus_tag="IRB70_001839"
     CDS             complement(11047..12420)
                     /gene="argH"
                     /locus_tag="IRB70_001839"
                     /EC_number="4.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate lyase"
                     /protein_id="HBC0631759.1"
                     /translation="MALWGGRFTQAADQRFKQFNDSLRFDYRLAEQDIVGSVAWSKAL
                     VTVGVLTAEEQAQLEEALNVLLEDVRARPQQILESDAEDIHSWVESKLIDKVGQLGKK
                     LHTGRSRNDQVATDLKLWCKDTVSELLTANRQLQSALVETAQNNQDAVMPGYTHLQRA
                     QPVTFAHWCLAYVEMLARDESRLQDALKRLDVSPLGCGALAGTAYEIDREQLAGWLGF
                     ASATRNSLDSVSDRDHVLELLSAAAIGMVHLSRFAEDLIFFNTGEAGFVELSDRVTSG
                     SSLMPQKKNPDALELIRGKCGRVQGALTGMMMTLKGLPLAYNKDMQEDKEGLFDALDT
                     WLDCLHMAALVLDGIQVKRPRCQEAAQQGYANATELADYLVAKGVPFREAHHIVGEAV
                     VEAIRQGKPLEELPLSELQKFSQVIGEDVYPILSLQSCLDKRAAKGGVSPQQVAQAIA
                     FAQARLE"
     gene            complement(12481..13257)
                     /gene="argB"
                     /locus_tag="IRB70_001840"
     CDS             complement(12481..13257)
                     /gene="argB"
                     /locus_tag="IRB70_001840"
                     /EC_number="2.7.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418394.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylglutamate kinase"
                     /protein_id="HBC0631760.1"
                     /translation="MMNPLIIKLGGVLLDSEEALERLFSALVNYRESHQRPLVIVHGG
                     GCVVDELMKGLNLPVKKKNGLRVTPADQINIITGALAGTANKTLLAWAKKHQIASVGL
                     FLGDGDSVKVTQLDEELGHVGLAQPGSPKLINSLLENGYLPVVSSIGVTDEGQLMNVN
                     ADQAATALAATLGADLILLSDVSGILDGKGQRIAEMTAAKAEQLIEQGIITDGMIVKV
                     NAALDAARTLGRPVDIASWRHAEQLPALFNGMPMGTRILA"
     gene            complement(13265..14269)
                     /gene="argC"
                     /locus_tag="IRB70_001841"
     CDS             complement(13265..14269)
                     /gene="argC"
                     /locus_tag="IRB70_001841"
                     /EC_number="1.2.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyl-gamma-glutamyl-phosphate reductase"
                     /protein_id="HBC0631761.1"
                     /translation="MLNTLIVGASGYAGAELVTYVNRHPHMNITALTVSAQSNDAGKL
                     ISDLHPQLKGIVDLPLQPMSDISEFSPGVDVVFLATAHEVSHDLAPQFLEAGCVVFDL
                     SGAFRVNDAAFYEKYYGFTHQYPELLEQAAYGLAEWCGNKLKEANLIAVPGCYPTAAQ
                     LALKPLIDADLLDLIQWPVINATSGVSGAGRKAAISNSFCEVSLQPYGVFTHRHQPEI
                     ATHLGADVIFTPHLGNFPRGILETITCRLKSGVTQAQVAQVLQQAYAHKPLVRLYDKG
                     VPALKNVVGLPFCDIGFAVQGEHLIIVATEDNLLKGAAAQAVQCANIRFGYAETQSLI
                     "
     gene            14423..15574
                     /gene="argE"
                     /locus_tag="IRB70_001842"
     CDS             14423..15574
                     /gene="argE"
                     /locus_tag="IRB70_001842"
                     /EC_number="3.5.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetylornithine deacetylase"
                     /protein_id="HBC0631762.1"
                     /translation="MKNKLPPFIEIYRALIATPSISATEEALDQSNADLITLLADWFK
                     DLGFNVEVQPVPGTRNKFNMLASTGQGAGGLLLAGHTDTVPFDDGRWTRDPFTLTEHD
                     GKLYGLGTADMKGFFAFILDALRDVDVTKLAKPLYILATADEETSMAGARYFAETTAL
                     RPDCAIIGEPTSLQPVRAHKGHISNAIRIMGQSGHSSDPARGVNAIELMHDAIGHILQ
                     LRDNLKERYHYEAFTVPYPTLNLGHIHGGDASNRICACCELHMDIRPLPGMTLNELNG
                     LLNDALAPVSERWPGRLTVDELHPPIPGYECPPNHQLVEVVEKLLGAKTEVVNYCTEA
                     PFIQTLCPTLVLGPGSINQAHQPDEYLETRFIKPTRELITQVIHHFCWH"
     gene            15876..18527
                     /gene="ppc"
                     /locus_tag="IRB70_001843"
     CDS             15876..18527
                     /gene="ppc"
                     /locus_tag="IRB70_001843"
                     /EC_number="4.1.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004203687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxylase"
                     /protein_id="HBC0631763.1"
                     /translation="MNEQYSALRSNVSMLGKVLGETIKDALGEHILERVETIRKLSKS
                     SRAGNDANRQELLTTLQNLSNDELLPVARAFSQFLNLANTAEQYHSISPKGEAASNPE
                     VIARTLRKLKNQPELSEDTIKKAVESLSLELVLTAHPTEITRRTLIHKMVEVNACLKQ
                     LDNKDIADYEHNQLMRRLRQLIAQSWHTDEIRKLRPSPVDEAKWGFAVVENSLWQGVP
                     NYLRELNEQLEENLGYKLPVEFVPVRFTSWMGGDRDGNPNVTADITRHVLLLSRWKAT
                     DLFLKDIQVLVSELSMVEATPELLALVGEEGAAEPYRYLMKNLRSRLMATQAWLEARL
                     KGEELPKPEGLLTQNEELWEPLYACYQSLQACGMGIIANGDLLDTLRRVKCFGVPLVR
                     IDIRQESTRHTEALGELTRYLGIGDYESWSEADKQAFLIRELNSKRPLLPRNWQPSAE
                     TREVLDTCQVIAEAPQGSIAAYVISMAKTPSDVLAVHLLLKEAGIGFAMPVAPLFETL
                     DDLNNANDVMTQLLNIDWYRGLIQGKQMVMIGYSDSAKDAGVMAASWAQYQAQDALIK
                     TCEKAGIELTLFHGRGGSIGRGGAPAHAALLSQPPGSLKGGLRVTEQGEMIRFKYGLP
                     EITVSSLSLYTGAILEANLLPPPEPKESWRRIMDELSVISCDLYRGYVRENKDFVPYF
                     RSATPEQELGKLPLGSRPAKRRPTGGVESLRAIPWIFAWTQNRLMLPAWLGAGTALQK
                     VVEDGKQSELEAMCRDWPFFSTRLGMLEMVFAKADLWLAEYYDQRLVDKALWPLGKEL
                     RNLQEEDIKVVLAIANDSHLMADLPWIAESIQLRNIYTDPLNVLQAELLHRSRQAEKE
                     GHEPDPRVEQALMVTIAGIAAGMRNTG"
     gene            18710..20443
                     /locus_tag="IRB70_001844"
     CDS             18710..20443
                     /locus_tag="IRB70_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase CptA"
                     /protein_id="HBC0631764.1"
                     /translation="MHSTEVQAKPLFSWKALGWALLYFWFFSTLLQAIIYISGYSGTN
                     GIRDSLLFSSLWLIPAFLFPKRIKIIAAVIGVVLWAASLAALCYYVIYGQEFSQSVLF
                     VMFETNTNEASEYLSQYFSLKIVLIALAYTAVAVLLWTRLRPVYIPKPWRYVVSFALL
                     YGLILHPIAMNTFIKNKPFEKALDNLASRMEPAAPWQFLTGYYQYRQQLNSLTKLLNE
                     NNALPPLANFKDESGNEPRTLVLVIGESTQRGRMSLYGYPRETTPELDALHKTDPNLT
                     VFNNVVTSRPYTIEILQQALTFANEKNPDLYLTQPSLMNMMKQAGYKTFWITNQQTMT
                     ARNTMLTVFSRQTDKQYYMNQQRTQSAREYDTNVLKPFQEVLKDPAPKKLIIVHLLGT
                     HIKYKYRYPENQGKFDGNTDHVPPGLNAEELESYNDYDNANLYNDHVVASLIKDFKAA
                     DPNGFLVYFSDHGEEVYDTPPHKTQGRNEDNPTRHMYTIPFLLWTSEKWQATHPRDFS
                     QDVDRKYSLAELIHTWSDLAGLSYDGYDPTRSVVNPQFKETTRWIGNPYKKNALIDYD
                     TLPYGDQVGNQ"
     gene            20592..21443
                     /locus_tag="IRB70_001845"
     CDS             20592..21443
                     /locus_tag="IRB70_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0631765.1"
                     /translation="MYHDVSYLLSRLINGPLSLRQIYFASSNGPVPDLAYQVDFPRLE
                     IVLEGEFVDTGAGATLVPGDVLYVPAGGWNFPQWQAPATTFSVLFGKQQLGFSVVQWD
                     GKQYQNLAKQHVARRGPRIGSFLLQTLNEMQMQSQEQQTARLIVASLLSHCRDLLGSQ
                     IQTASRSQALFEAIRDYIDERYASALTRESVAQAFYISPNYLSHLFQKTGAIGFNEYL
                     NHTRLEHAKTLLKGYDLKVKEVAHACGFVDSNYFCRLFRKNTERSPSEYRRQYHSQLT
                     EKPTTPE"
     gene            complement(21430..21771)
                     /locus_tag="IRB70_001846"
     CDS             complement(21430..21771)
                     /locus_tag="IRB70_001846"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBC0631766.1"
                     /translation="MAYLVAVTACVSGVAHTYMAAERLEKLCQLEKWGVSIETQGALG
                     TENRLADEDIRRADVALLITDIELAGAERFEHCRYVQCSIYAFLREPQRVMSAVRKVL
                     SAPQQIHLILE"
     gene            complement(21773..22651)
                     /locus_tag="IRB70_001847"
     CDS             complement(21773..22651)
                     /locus_tag="IRB70_001847"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709752.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[formate-C-acetyltransferase]-activating enzyme"
                     /protein_id="HBC0631767.1"
                     /translation="MTSSAGQRISCNVVETRRDDVARIFNIQRYSLNDGEGIRTVVFF
                     KGCPHLCPWCANPESISGKIQTVRREAKCLHCAKCLRDADECPSGAFERIGRDISLDA
                     LEREVMKDDIFFRTSGGGVTLSGGEVLMQAEFATRFLQRLRLWGVSCAIETAGDAPAS
                     KLLPLAKLCDEVLFDLKIMDATQARDVVKMNLPRVLENLRLLVSEGVNVIPRLPLIPG
                     FTLSRENMQQALDVLIPLNIRQIHLLPFHQYGEPKYRLLGKTWSMKEVSAPSSADVTT
                     MREMAERAGFQVTVGG"
     gene            complement(22617..24914)
                     /locus_tag="IRB70_001848"
     CDS             complement(22617..24914)
                     /locus_tag="IRB70_001848"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBC0631768.1"
                     /translation="MTNRISRLKTALFANTREISLERALLYTASHRQTEGEPVILRRA
                     KATAYILEHVEISIRDEELIAGNRTVKPRAGIMSPEMDPYWLLKELDQFPTRPQDRFA
                     ISEEDKRIYREELFPYWEKRSMKDFINGQMTDEVKAATSTQIFSINQTDKGQGHIIID
                     YPRLLNHGLGELVAQMQQHCQQQPENHFYQAALLLLEASQKHILRYAELAETMAANCT
                     DAQRREELLTIAEISRHNAQHKPQTFWQACQLFWYMNIILQYESNASSLSLGRFDQYM
                     LPFYQASLTLGEDPAFLKELLESLWVKCNDIVLLRSTSSARYFAGFPTGYTALLGGLT
                     ENGRSAVNVLSFLCLDAYQSVQLPQPNLGVRTNALIDTPFLMKTAETIRLGTGIPQIF
                     NDEVVVPAFLNRGVSLEDARDYSVVGCVELSIPGRTYGLHDIAMFNLLKVMEICLHEN
                     EGNAALTYEGLLEQIRAKISHYITLMVEGSNICDIGHRDWAPVPLLSSFISDCLEKGR
                     DITDGGARYNFSGVQGIGIANLSDSLHALKGMVFEQQRLSFDELLSVLKANFATPEGE
                     KVRARLINRFEKYGNDIDEVDNISAELLRHYCKEVEKYQNPRGGYFTPGSYTVSAHVP
                     LGSVVGATPDGRFAGEQLADGGLSPMLGQDAQGPTAVLKSVSKLDNTLLSNGTLLNVK
                     FTPATLEGEAGLRKLADFLRAFTQLKLQHIQFNVVNADTLREAQQRPQDYAGLVVRVA
                     GYSAFFVELSKEIQDDIIRRTAHQL"
     gene            complement(24965..25285)
                     /locus_tag="IRB70_001849"
     CDS             complement(24965..25285)
                     /locus_tag="IRB70_001849"
                     /EC_number="2.7.1.202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIB"
                     /protein_id="HBC0631769.1"
                     /translation="MTKIIAVTACPSGVAHTYMAAEALESAAKAKGWEVKVETQGSIG
                     LENELTAEDVASADMVILTKDIGIKFEERFAGKTIVRVNISDAVKRADAIMSKIEAHL
                     AQTA"
     gene            complement(25300..26379)
                     /locus_tag="IRB70_001850"
     CDS             complement(25300..26379)
                     /locus_tag="IRB70_001850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit EIIC"
                     /protein_id="HBC0631770.1"
                     /translation="MNELVQILKNTRQHLMTGVSHMIPFVVSGGILLAVSVMLYGKGA
                     VPDAVADPNLKKLFDIGVAGLTLMVPFLAAYIGYSIAERSALAPCAIGAWVGNSFGAG
                     FFGALIAGIIGGIVVHYLKKIPVHKVLRSVMPIFIIPIVGTLITAGIMMWGLGEPVGA
                     LTNSLTQWLQGMQQGSIVMLAVIMGLMLAFDMGGPVNKVAYAFMLICVAQGVYTVVAI
                     AAVGICIPPLGMGLATLIGRKNFSAEERETGKAALVMGCVGVTEGAIPFAAADPLRVI
                     PSIMVGSVCGAVTAALVGAQCYAGWGGLIVLPVVEGKLGYIAAVAVGAVVTAVCVNVL
                     KSLARKNGSSTDEKEDDLDLDFEIN"
     gene            26688..29189
                     /gene="ptsP"
                     /locus_tag="IRB70_001851"
     CDS             26688..29189
                     /gene="ptsP"
                     /locus_tag="IRB70_001851"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBC0631771.1"
                     /translation="MALIVEFICELPNGVHARPASHVETLCNTFSSQIEWHNLRTDRK
                     GNAKSALALIGTDTLVGDNCQLLISGADEQEAHQRLSQWLRDEFPHCDAPLAEVKSDE
                     LEPLPVSLTNLNPQIIRARTVCSGSAGGILTPISSLDLNALGNLPAAKGVDAEQSALE
                     NGLTLVLKNIEFRLLDSDGATSAILEAHRSLAGDTSLREHLLAGVSAGLSCAEAIVAS
                     AHHFCEEFARSSSSYLQERALDVRDVCFQLLQQIYGEQRFPAPGKLTQPAICMADELT
                     PSQFLELDKNHLKGLLLKSGGTTSHTVILARSFNIPTLVGVDIDALTPWQHQTIYIDG
                     NAGAIVVEPGESVARYYQQEARVQDALREQQRVWLTQQARTADGIRIEIAANIAHSVE
                     AQAAFGNGAEGVGLFRTEMLYMDRTSAPGESELYNIFCQALESANGRSIIVRTMDIGG
                     DKPVDYLNIPAEANPFLGYRAVRIYEEYASLFTTQLRSILRASAHGSLKIMIPMISSM
                     EEILWVKEKLAEAKQQLRNEHIPFDEKIQLGIMLEVPSVMFIIDQCCEEIDFFSIGSN
                     DLTQYLLAVDRDNAKVTRHYNSLNPAFLRALDYAVQAVHRQGKWIGLCGELGAKGSVL
                     PLLVGLGLDELSMSAPSIPAAKARMAQLDSRECRQLLNQAMACRTSLEVEHLLAQFRM
                     TQQDAPLVTAECITLESDWRSKEEVLKGMTDNLLLAGRCRYPRKLEADLWAREAVFST
                     GLGFSFAIPHSKSEHIEQSTISVARLAAPVRWGDDEAQFIIMLTLNKHAAGDQHMRIF
                     SRLARRIMHEEFRNALVNAASADAIASLLQHELEL"
     gene            29201..29863
                     /gene="fsa"
                     /locus_tag="IRB70_001852"
     CDS             29201..29863
                     /gene="fsa"
                     /locus_tag="IRB70_001852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBC0631772.1"
                     /translation="MELYLDTANVAEVERLARIFPIAGVTTNPSIIAASKESIWEVLP
                     RLQKAIGDEGILFAQTMSRDAQGMVEEAKRLRDAIPGIVVKIPVTSEGLAAIKMLKKE
                     GITTLGTAVYSAAQGLLAALAGAKYVAPYVNRVDAQGGDGIRTVQELQALLEMHAPES
                     MVLAASFKTPRQALDCLLAGCESITLPLDVAQQMLNTPAVESAIEKFENDWNAAFGTT
                     HL"
     gene            29874..30977
                     /gene="gldA"
                     /locus_tag="IRB70_001853"
     CDS             29874..30977
                     /gene="gldA"
                     /locus_tag="IRB70_001853"
                     /EC_number="1.1.1.6"
                     /EC_number="1.1.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418380.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional L-1,2-propanediol
                     dehydrogenase/glycerol dehydrogenase"
                     /protein_id="HBC0631773.1"
                     /translation="MDRIIQSPGKYIQGADVINRLGEYLKPLAERWLVVGDKFVLGFA
                     QSTVEKSFKDAGLVVEIAPFGGECSQNEIDRLRGIAETAQCGAILGIGGGKTLDTAKA
                     LAHFMGVPVAIAPTIASTDAPCSALSVIYTDEGEFDRYLLLPNNPNMVIVDTKIVAGA
                     PARLLAAGIGDALATWFEARACSRSGATTMAGGKCTQAALALAELCYNTLLEEGEKAM
                     LAAEQHVVTPALERVIEANTYLSGVGFESGGLAAAHAVHNGLTAIPDAHHYYHGEKVA
                     FGTLTQLVLENAPVEEIETVAALSHAVGLPITLAQLDIKEDVPAKMRIVAEAACAEGE
                     TIHNMPGGATPDQVYAALLVADQYGQRFLQEWE"
     gene            31308..31925
                     /locus_tag="IRB70_001854"
     CDS             31308..31925
                     /locus_tag="IRB70_001854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1287 domain-containing protein"
                     /protein_id="HBC0631774.1"
                     /translation="MKASLVLVSLLTAFTSHSLKSPAVPPTVVQIQANTNLAIADGAR
                     QQIGSTLFYDPAYVQLTYPGGDVPQERGVCSDVVIRALRSQKVDLQKLVHEDMAKNFA
                     AYPQKWQLKRPDSNIDHRRVPNLETWFTRHDKTRPTSKNPSDYQSGDIVSWRLDNGLA
                     HIGVVSDGFARDGTPLVIHNIGAGAQEEDVLFSWRMVGHYRYFVK"
     gene            complement(31952..32857)
                     /gene="yijE"
                     /locus_tag="IRB70_001855"
     CDS             complement(31952..32857)
                     /gene="yijE"
                     /locus_tag="IRB70_001855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418378.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine transporter YijE"
                     /protein_id="HBC0631775.1"
                     /translation="MSAAGKSNPLAISGLVVLTLIWSYSWIFMKQVTSYIGAFDFTAL
                     RCIFGALVLFIVLLLRGRGMRPTPFKYTLAIALLQTCGMVGLAQWALVSGGAGKVAIL
                     SYTMPFWVVIFAALFLGERLRRGQYFAILIAAFGLFLVLQPWQLDFSSMKSAMLAILS
                     GVSWGASAIVAKRLYARHPRVDLLSLTSWQMLYAALVMSVVALLVPQREIDWQPTVFW
                     ALAYSAILATALAWSLWLFVLKNLPASIASLSTLAVPVCGVLFSWWLLGENPGAVEGS
                     GIVLIVLALALVSRKKKEAVSVKNI"
     gene            complement(32951..35131)
                     /gene="katG"
                     /locus_tag="IRB70_001856"
     CDS             complement(32951..35131)
                     /gene="katG"
                     /locus_tag="IRB70_001856"
                     /EC_number="1.11.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catalase/peroxidase HPI"
                     /protein_id="HBC0631776.1"
                     /translation="MSTSDDIHNTTATGKCPFHQGGHDQSAGGGTTTRDWWPNQLRVD
                     LLNQHSNRSNPLGEDFDYRKEFSKLDYYGLKKDLKALLTESQPWWPADWGSYAGLFIR
                     MAWHGAGTYRSIDGRGGAGRGQQRFAPLNSWPDNVSLDKARRLLWPIKQKYGQKISWA
                     DLFILAGNVALENSGFRTFGFGAGREDVWEPDLDVNWGDEKAWLTHRHPEALAKAPLG
                     ATEMGLIYVNPEGPDHSGEPLSAAAAIRATFGNMGMNDEETVALIAGGHTLGKTHGAG
                     PTSNVGPDPEAAPIEEQGLGWASTYGSGVGADAITSGLEVVWTQTPTQWSNYFFENLF
                     KYEWVQTRSPAGAIQFEAVDAPEIIPDPFDPSKKRKPTMLVTDLTLRFDPEFEKISRR
                     FLNDPQAFNEAFARAWFKLTHRDMGPKSRYIGPEVPKEDLIWQDPLPQPIYNPTEQDI
                     IDLKFAIADSGLSVSELVSVAWASASTFRGGDKRGGANGARLALMPQRDWDVNAAAVR
                     ALPVLEKIQKESGKASLADIIVLAGVVGVEKAASAAGLSIHVPFAPGRVDARQDQTDI
                     EMFELLEPIADGFRNYRARLDVSTTESLLIDKAQQLTLTAPEMTALVGGMRVLGANFD
                     GSKNGVFTDRVGVLSNDFFVNLLDMRYEWKATDESKELFEGRDRETGEVKYTASRADL
                     VFGSNSVLRAVAEVYASSDAHEKFVKDFVAAWVKVMNLDRFDLL"
     gene            complement(35460..36350)
                     /gene="metF"
                     /locus_tag="IRB70_001857"
     CDS             complement(35460..36350)
                     /gene="metF"
                     /locus_tag="IRB70_001857"
                     /EC_number="1.5.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylenetetrahydrofolate reductase"
                     /protein_id="HBC0631777.1"
                     /translation="MSFFHASQRDALNQSLAEVQGQINVSFEFFPPRTSEMEQTLWNS
                     IDRLSNLKPKFVSVTYGANSGERDRTHSIIKGIKDRTGLEAAPHLTCIDATPDELRTI
                     ARDYWNNGIRHIVALRGDLPPGSGKPEMYASDLVTLLKEVADFDISVAAYPEVHPEAK
                     SAQADLLNLKRKVDAGANRAITQFFFDVESYLRFRDRCVSAGIDVEIIPGILPVSNFK
                     QAKKFADMTNVRIPAWMAQMFDGLDDDAETRKLVGANIAMDMVKILSREGVKDFHFYT
                     LNRAEMSYAICHTLGVRPGL"
     gene            complement(36732..38285)
                     /locus_tag="IRB70_001858"
     CDS             complement(36732..38285)
                     /locus_tag="IRB70_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional metallophosphatase/5'-nucleotidase"
                     /protein_id="HBC0631778.1"
                     /translation="MKIKMLAAGIALTLPFWACAKDVTIIYTNDLHAHVEPYKVPWIA
                     DGKRDIGGWANITTLVKQEKAKNKATWFFDAGDYFTGPYISSLTKGKAIIDIMNTMPF
                     DAVTIGNHEFDHGWDNTLLQLSQAKFPIVQGNVFYQNSSKSFWDKPYTIIEKDGVKIG
                     VIGLHGVFAFNDTVSAATRVGIEARDEIKWLQRYIDELKGKVDLTVALIHEGVPARQS
                     SMGGTDVRRALDKDIQTASQVKGLDILITGHAHVGTPEPIKVGNTLILSTDSGGIDVG
                     KLVLDYKEKPHDFTVKNFELKTIYADEWKPDPQTKQVIDGWNKKLDEVVQQTVAQSPV
                     ELKRAYGESASLGNLAADALLVAAGKNTQLALTNSGGIRNEIPAGAITMGGVISTFPF
                     PNELVTMELTGKQLRSLMEHGASLSNGVLQVSKGLEMKYDSSKPVGQRVITLTLNGKP
                     IEDATVYSIATQSFLADGGDGFTAFTEGKARNTTGGYYVYHAVVDYFKAGNTITDEQI
                     NGMRVKDIK"
     gene            38418..39548
                     /locus_tag="IRB70_001859"
     CDS             38418..39548
                     /locus_tag="IRB70_001859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytoplasmic protein"
                     /protein_id="HBC0631779.1"
                     /translation="MSTLFTINACKSFGCRNLGQPTSTDYSWPDYRLGYPALHCRACG
                     SYPPLFDEQQFRDWLSVHLSTFATEKGHFCPVCYGTKTICYGHNPQGSQRIQCRNCKK
                     VWTPKQYQKEITPPEIIETVALLVPFQGASGGQKLYVLISFDALRGNILHLSTNYTQH
                     QAGESLHYRYRGNAEPELHESNIVQRVDMREAQFLRRSQFDEIQYGSAALKRNAKGVI
                     LRPVITAHGHFRVLNILFPTVKTHVISHECFLRGAIITAWAELFRQQQGEIWFIEEEI
                     ADYTDNTPWRFQGKTYHGWWKNQWQLWVQGKNRKMVCALTGGNNSKAVMLSFATSRHF
                     IDWLHKQAVFTHSTPLSAGRVTQILLSLAQDYNNCARRLISD"
     gene            complement(39512..41944)
                     /gene="metL"
                     /locus_tag="IRB70_001860"
     CDS             complement(39512..41944)
                     /gene="metL"
                     /locus_tag="IRB70_001860"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000110794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase II"
                     /protein_id="HBC0631780.1"
                     /translation="MSVIAQAGAKGRQLHKFGGSSLADVKCYLRVAGIMAEYSQPDDM
                     MVVSAAGSTTNQLINWLKLSQTDRLSAHQVQQTLRRYQCDLISGLLPAEEADSLISAF
                     VSDLERLAALLDSGINDAVYAEVVGHGEVWSARLMSAVLNQQGLPAAWLDAREFLRAE
                     RAAQPQVDEGLSYPLLQQLLVQHPGKRLVVTGFISRNNAGETVLLGRNGSDYSATQIG
                     ALAGVSRVTIWSDVAGVYSADPRKVKDACLLPLLRLDEASELARLAAPVLHVRTLQPV
                     SGSEIDLQLRCSYTPDQGSTRIERVLASGTGARIVTSHDDVCLIEFQVPASQDFKLAH
                     KEIDQILKRAQVRPLAVGVHNDRQLLQFCYTSEVADSALKILDEAGLPGELRLRQGLA
                     LVAMVGAGVTRNPLHCHRFWQQLKGQPVEFTWQSDDGISLVAVLRTGPTESLIQGLHQ
                     SVFRAEKRIGLVLFGKGNIGSRWLELFAREQSTLSARTGFEFVLAGVVDSRRSLLSYD
                     GLDASRALAFFNDEAVEQDEESLFLWMRAHPYDDLVVLDVTASQQLADQYLDFASHGF
                     HVISANKLAGASDSNKYRQIHDAFEKTGRHWLYNATVGAGLPINHTVRDLIDSGDTIL
                     SISGIFSGTLSWLFLQFDGSVPFTELVDQAWQQGLTEPDPRDDLSGKDVMRKLVILAR
                     EAGYNIEPDQVRVESLVPTHCEGGSIDHFFENGDELNEQMVQRLEAAREMGLVLRYVA
                     RFDANGKARVGVEAVREDHPLASLLPCDNVFAIESRWYRDNPLVIRGPGAGRDVTAGA
                     IQSDINRLAQLL"
     gene            complement(41947..43107)
                     /gene="metB"
                     /locus_tag="IRB70_001861"
     CDS             complement(41947..43107)
                     /gene="metB"
                     /locus_tag="IRB70_001861"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBC0631781.1"
                     /translation="MTRKQATIAVRSGLNDDEQYGCVVPPIHLSSTYNFTGFNEPRAH
                     DYSRRGNPTRDVVQRALAELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYG
                     GSYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKIC
                     HLAREVGAVSVVDNTFLSPALQNPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDV
                     VTELAWWANNIGVTGGAFDSYLLLRGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLY
                     HPSLPENQGHEIAARQQKGFGAMLSFELDGDEQTLRRFLGGLSLFTLAESLGGVESLI
                     SHAATMTHAGMAPEARAAAGISETLLRISTGIEDGEDLIADLENGFRAANKG"
     gene            43384..43701
                     /gene="metJ"
                     /locus_tag="IRB70_001862"
     CDS             43384..43701
                     /gene="metJ"
                     /locus_tag="IRB70_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015855437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="met regulon transcriptional regulator MetJ"
                     /protein_id="HBC0631782.1"
                     /translation="MAEWSGEYISPYAEHGKKSEQVKKITVSIPLKVLKILTDERTRR
                     QVNNLRHATNSELLCEAFLHAFTGQPLPDDADLRKERSDEIPEAAKEIMREMGINPET
                     WEY"
     gene            43761..44369
                     /locus_tag="IRB70_001863"
     CDS             43761..44369
                     /locus_tag="IRB70_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiX family permuted papain-like enzyme"
                     /protein_id="HBC0631783.1"
                     /translation="MKIRLLIPGLLVSVPAFAWQPQTGDIIFQISRSSQSKAIQLATH
                     SDYSHTGMLVIRNKKPYVFEAVGPVKYTPLKQWIAHGEKGKYVVRRVEGGLSVEQQQK
                     LAQTAKRYLGKPYDFSFSWSDDRQYCSEVVWKVYQNALGMRVGEQQKLKEFDLSNPLV
                     QTKLKERYGKNIPLEETVVSPQAVFDAPQLTTVAKEWPLFSW"
     gene            44514..45189
                     /locus_tag="IRB70_001864"
                     /pseudo
     CDS             44514..45189
                     /locus_tag="IRB70_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477181.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT        11273 a        12396 c        11225 g        10458 t
ORIGIN      
        1 ccgcttcgct ttttctcagc ggtgcggggt gtgcataata cgctttcccg ctacagagtc
       61 aagcattttt ttgcttttct ctgttgagat tctcaggaga accccgctga cccggcggcg
      121 tgtttgccgt tgttccgtgt cagtggtggc gcattatagg gagttattcc ggcctgacaa
      181 gaggaaattt aaaataattt tctgaccgcg caacattcaa ccaaatcagc ctaaaactgc
      241 cagtttttcg agcgtttcga agccgtaacg ctgtaaaacg ggcaataatt gttcagcttc
      301 tggcgtcatt gccatacaaa aggcaatatt cgcatcggca gattttgcat ccggggcttc
      361 atgttctaac agccaggccg ttcggcgagc aatcgctgcg ccagaatcca ccagccgggt
      421 tccctctggc agcacctgta agagttcttc ttgtagtaga gggaaatggg tgcaacccaa
      481 tacaacggta tctggcggct ctttcattct taaccacgga cgcaagatac gttttagcgc
      541 atccagagaa acatcttcgc catgcagctt cgcttcagcc aactcaacca tctctgccga
      601 gcccagcatt tctatctggc attcattagc gaaacgcgcg atcagctcat gagtataaga
      661 acgtttaact gttccgcggg ttgccagtaa tccgacaatg ccatttgccg tcagacgtgc
      721 agcaggttta atcgccggca cgacaccaac aaccgggaag tcgaactttt cgcgtaatgc
      781 aggaagtgaa acggtactgg cagtgttgca agcgaccaca gccagcgcaa ggggataacg
      841 tttttgcact gcggtgacaa ttgccaccac tcgctcaaca ataaacgctt cgcttttttc
      901 gccatacggg aaagcgacgt tatcgaaagc ataaatgtaa tggagatccg gtaagagatg
      961 ccggatctcg tcatagaccg acaacccacc gacgccggag tcaaacacca gcacggtggg
     1021 acgtggttca gaaggtgtag ctgccagaca aggtgtattc ccgtcctgca gtttggtagc
     1081 catagactgt ctcataatct ttgtcgaaca ggttggctat tttaccacga actgtcagat
     1141 gagaggtgac cggatacgca accgcaagat cccacaagct cacaccgccc attttaacgg
     1201 tttgataagg ataagatgag taatccttat catagcgagt gcctaaatac tgataagtaa
     1261 taccccagtc gaagtcatac aattgccagt cgagctggta tttcacctgc tgtttagcac
     1321 ggcgtaacaa cggcacgtcg gtaatcgcat tacgcgcatc gacataatca taactcacag
     1381 tatgcgtcag tggtccggta tcaaaattgg cggtcgcctc gaccccctta atccgcgctt
     1441 tcccttcgtt gtaatatttc agggtgtgat catcataatc gatcaaatca ctgacatcgt
     1501 tacgatatcc ggaaatacgc cagttcaccc cagcggttaa gccttcaaac gcgccttccc
     1561 actgtttgct tttctcagga ttcagattcg gatttccgta gaaaccatac agttgcccaa
     1621 gattaggtgc cttgtacgac gtgccataag aagcgataaa acgatagcct tcgatgaatt
     1681 cccaaccggc actcgtttgc caggttccat gacgaccaaa ctgtgagtta tcgtcgctgc
     1741 gtgctgcgcc ttcaaaggta aaatcgccga cttgttgcag cccggtcaga tagatgccgg
     1801 tattacgttg atcatatcca tcctcaacat aacctgtacc cggcgtcgta gtctgtttct
     1861 gccagtcgac acccgcacca atactaccgt gaccaacgat gacattgttt gcccactgga
     1921 cggtgtattg cttcatctca tccagcgtcg cggacgaatc ataacgacca taatggggat
     1981 cgtagttgta atctttgcta tggctatagc tggtaatgag ttgtgattta atcagttcgc
     2041 cgttatagcg cagcccggcg tcccaacttt ggctatagag tttacgggta tcgagcaacg
     2101 gtgagccggg agaataatac gcgtcataat tggtacggtt atcatagcca tagccgcgca
     2161 caaagccgct ccaggcatca gtaaagttat gctccagcgc gccataaagc gttttactta
     2221 aaaaaccatc gttatctgtc tgcgcttgcg ttccggtatt accataggca acaacatcat
     2281 aaccatgagt atgggcataa tcgcccaaca gcgttacccg tgtcttatcc cccagttgtt
     2341 gctgcgtgga gacatcatag ttctgataac tattgcttcc ccaccctgct gaaatttccg
     2401 ttccgggttc atcgcgcgtc gtgatgatat tcaccacccc gcctattgca tcggaaccat
     2461 aaacagcgga gcgcggtcca cggatatatt caatacgctg gacaagcgca atagggaact
     2521 ggctaaggtc ggcagaacca ctcactcccg ccagattcag gcggacgcca tcaattaaca
     2581 ccagcacatg actggcattt gtaccgcgaa taaaaataga tgagagctga cctgaaccgc
     2641 cgttttgggt gatatcgaca cccggaagac ggcgcagcac atcattgacc gaggtcgact
     2701 gccagcggtc aatatcctga cgggtcacaa cggtggttgg tgcaagcaca gtgctgcgcg
     2761 gctgttcaaa acggttagca gtaacgacga gagtatccgg gctggtatcc tgtgcccaag
     2821 cagaaaaggc tgtgacagaa cacgccgtca gcagcgaagc ttttttaatc attgtaaagc
     2881 atccacaata gaagaaggat gccgcaggtt tcatcaatat tacgcgatga tgagaaccag
     2941 atgcgacgtt agccggcagg tcttcgggct tggaggggta tctaagatac taagagatga
     3001 tgacttccca ccggatggca gtgtccgcat aacgcaatca tcgcaccttt ccttaccgct
     3061 gcgcgtcagc tccagattcg cactggattc cctattaact cacaggaccg gcaagtggat
     3121 gctacaggtt gtaacaagtt actgtccaga cgtagctcac aaataggaat tcatcaagat
     3181 ctggacatct gatgagcaat ccctacaatc gccgcgtact ttaatttttc aggatacatc
     3241 atgacccccg aacaccttcc aacagaacag tatgaagcgc agttagccga aaaagtggta
     3301 cgtttgcaaa gtatgatggc accgttttct gacctggttc cggaagtgtt tcgctcgccg
     3361 gtcagtcatt accggatgcg tgcggagttc cgcatctggc acgatggcga tgacctgtac
     3421 cacatcattt tcgatcaaca aaccaaaagc cgcatccgcg tggatagctt ccccgccgcc
     3481 agtgaactta tcaaccagtt gatgacggcg atgattgcgg gtgtgcgtaa taatcccgtt
     3541 ctgcgccaca agttgttcca gattgattac ctcaccacgc tgagtaatca ggcggtggtt
     3601 tccctgctgt accataagaa gctggatgat gagtggcgtc aggaagcgga agccctgcgc
     3661 gatgcactgc gcgcgcagaa tctgaatgtg catctgattg gtcgggcaac gaaaaccaaa
     3721 atcgagctgg accaagatta catcgatgaa cgtctgccgg tcgcagggaa agagatgatc
     3781 taccgtcagg tagaaaacag ctttacccaa ccgaacgcgg cgatgaatat tcagatgctg
     3841 gaatgggcgc tggacgtcac caaaggctca aaaggcgatt tactggagct gtactgcggc
     3901 aacggtaact tctcattagc cctggcgcgc aattttgatc gggtattagc caccgaaatc
     3961 gccaagcctt cggtcgctgc cgcgcaatac aacattgccg ctaaccatat tgataacgtc
     4021 caaattattc gtatggcggc agaagaattt actcaggcga tgaatggtgt gcgcgagttt
     4081 catcgcctgc aagggatcga cttgaagagt tatcagtgcg aaaccatttt tgtcgaccca
     4141 ccgcgcagcg gtctggacag tgaaaccgag aaaatggtgc aggcgtatcc acgtattctg
     4201 tatatctcct gcaatccgga aacgttatgc aagaatctgg aaacattaag ccagacgcac
     4261 aaggttgaac gtctggctct gtttgatcag ttcccctaca cgcaccatat ggagtgcggc
     4321 gtattactga ccgcgaagta aaacctatgc cggatgcgcc agcatccggc atgataccga
     4381 ttactcagca acttcctgct tacggttacg catcttcgcg ccaatccaga acaccataat
     4441 gacggacagt actgccggga agaagttaga gccgatatcc ggatattccg cacgaactac
     4501 cgtgctgtac agcagtacgc cgagaataaa acaagcagca gccagacccg gcaagcctac
     4561 cggcatagtg cgattaagat aacgttgatg caggcagtaa actgtcagca ccagggaaat
     4621 aatcgggaat acagaaaatg gcacaatgga gctaaacagc gctgcgaaag taccattaat
     4681 cgataagcca gccaccagcg ccagcagcag cgtacctcta tcttgatttg cttgtttcat
     4741 tactcgtcct tcacatttcc cggaataatt gcggttttct cttgttcacg gcgataccag
     4801 taataagccc ctttcgaaat cattcgcagt tgcagtacca gtcgctcttc taattgccga
     4861 cgttgttcaa cgccgacgtc caacgcctcg gcacccgcac tgaagacaat cgtcaccatg
     4921 gcttcggctt gcgcttcagt aaacgcacgc ggcatatggt tttcgagttc cagatagtcc
     4981 gcaagttccg caatgaagtg ctgaatttca cgcgcaacgg cggcacgaaa cgcagcggag
     5041 gtgccggagc gttcccgcaa taataaccgg aaggcgttag gattattacc gatgaactcc
     5101 ataaatgtgg agaccgaggt gcggatcaca ctcccgcctt tggcgatacg ctgacgcgcc
     5161 tggcgcatga gttggcgtag cattaaaccg ctctcatcaa ccatggtcag acccagttcg
     5221 tctacgtcgc ggaaatgccg ataaaaagag gtgggagcaa tgcccgcttc acgcgccact
     5281 tcacgcaaac tcaggctggc gaagctgcgt tcagcactta attggctaaa tgcggcttcc
     5341 accagcgaac ggcgggtttt ttctttttgt tgcgctctta cgcccatcac gatgtctgaa
     5401 tccttgccaa aagtactgct ggcactatac cagagaatga acatactgga ttgctccagt
     5461 gttgtgaatg aacggtaacg caataaaaca tatttactgc aattctttgg ccggttcttt
     5521 tacgtacaac ggaaacctgc cgcttaaacg gagagtatcg tcgataaaaa tccaataaaa
     5581 cgttcaggtc aaaagtaaga aacagacaaa gcaaaggccg ctcacgatat agccagataa
     5641 atgacgggga tcaattggct tacccgcgat aaaatgttac cattctgttg cttttatgta
     5701 taagaacagg taagccctac catgccacat tcctacgatt acgatgccat agtaataggt
     5761 tccggccccg gcggcgaagg cgctgcaatg ggcctggtta agcaaggtgc gcgcgtcgca
     5821 gttatcgagc gttatcaaaa tgttggcggc ggttgcaccc actggggcac catcccgtcg
     5881 aaagctctcc gtcacgccgt cagccgcatt atagaattta atcaaaaccc actatacagc
     5941 gaccattccc gactgctccg ctcttctttt gccgatatcc ttaaccatgc cgataacgtg
     6001 attaaccaac aaacgcgcat gcgtcaggga ttttacgaac gtaatcactg tgaaatattg
     6061 caggggaacg ctcgctttgt tgacgagcat acgttggcgc tggattgccc ggacggcagc
     6121 gttgaaacac taaccgctga aaaatttgtt attgcctgcg gctctcgtcc atatcatcca
     6181 acagatgttg atttcaccca tccacgcatt tacgacagcg actcaattct tagcatgcac
     6241 cacgaaccgc gccatgtact tatctatggt gctggagtga tcggctgtga atatgcgtcg
     6301 atcttccgcg gtatggatgt aaaagtggat ctgatcaaca cccgcgatcg gctgttggcg
     6361 tttctcgatc aagagatgtc agattctctc tcctatcact tctggaacag tggcgtagtg
     6421 attcgtcaca acgaagagta cgagaagatc gaaggctgtg acgacggtgt gatcatgcat
     6481 ctgaagtcgg gtaaaaaact gaaagctgac tgtctgctct atgccaacgg tcgcaccggt
     6541 aataccgatt cgctggcgtt acagaacatt gggctggaaa ctgacagtcg cggacagctg
     6601 aaggtcaaca gcatgtatca gaccgcacag ccgcacgttt acgcggtggg cgacgtgatt
     6661 ggttatccga gcctggcgtc ggcagcctat gaccaggggc gcattgccgc gcaagcgctg
     6721 gtgaaaggtg aagccaacgc acatctgatt gaagatatcc ctaccggcat ttacaccatc
     6781 ccggaaatca gctctgtggg caaaaccgaa cagcagctaa ccgcgatgaa agtgccatat
     6841 gaagtgggcc gcgcccagtt taaacatctg gcacgtgcac aaatcgtcgg catgaacgtg
     6901 ggcacgctga aaattttgtt ccatcgggaa acaaaagaga ttctgggtat tcactgcttt
     6961 ggcgagcgcg ctgccgaaat tattcatatc ggtcaggcga ttatggaaca gaaaggtggc
     7021 ggcaacacta ttgagtactt cgtcaacacc acctttaact acccgacgat ggcggaagcc
     7081 tatcgggtag ctgcgctaaa tggcttaaac cgcctgtttt aacactttat cgaaatggcc
     7141 atccattctt gcgcggatgg cctctgccag ctgctcatag cggctgcgca gtggtgagcc
     7201 aggacgataa accaggccaa tagtgcggcg tggttccggc ttaatgcacg gcagataaac
     7261 aaccccatcg cgtttgcgct ccggcggcac agccagcgct ggcaataaag tgatcccgct
     7321 acctgccgcc accatgttgc gcagcgtctc caggctggtc gcgcggaagt gtgtatcttc
     7381 atccgccccg gcttcaaaac agaaccccat tgcctgatcg cgcaaacagt gaccatcttc
     7441 cagcatcagc agtttttctc ctgccagatc ggccatcggt acgcattcgc ggttcgccca
     7501 cgggtgatct tcatagatag ccagcaacat tggctcatca aacaacggca cttcaatgaa
     7561 tgcttcgctc tctttcacca gcgcgaggat cacgcaatcg agcttgccgc tgtccagttg
     7621 cgccagtaac tggtgggtct gtgcttcatg cagatacatt tccagctttg gaaaggtctg
     7681 gtgcagcatc gggataatat gcggtagcag gtacggtcca accgtgggaa tcaaaccaat
     7741 atgcagcggt ccggacatcg tctcgccctg ctggcttgcc atctctttaa ggactttcac
     7801 ctcacgcagc acggtacgcg cctgatccac cagcagcatt cccgcctggg tgaataacac
     7861 tttacggctg gtccgctcca gcaacatcac gcccagctca tcttccagct tacgaatttg
     7921 cccgctaagc gtcggctggc taacgtggca ggaatctgcc gcacgccgaa aatggcggtg
     7981 ttcagccaat gccaccaggt actcaagatc acgaatattc attatccatc ctccatcgcc
     8041 acgatagttc atggcgatag gtagaatagc aatgaacgat tatccctatc aagcattctg
     8101 actgataatt gctcacagaa acggagcggc acctctttta acccttgaag tcactgcccg
     8161 tttcgagagt ttctcaactc gaataactaa agccaacgtg aacttttgcg gatctccagg
     8221 atccgctttt tttattctac aggcccacag caagagagcc tgatagtaac agttactcaa
     8281 tccgatcttt gacaataaag aagtaacaca gcgccccggt gaacgtcaca caggccgcga
     8341 taaccagcgc cagattaaac gagtgcgtgg tatccactac ccaaccggtt acgatcggag
     8401 caaaggaagc aaaaacaaaa ctgccaaagt tttgaatccc ggcgatggaa gccacttttg
     8461 tttctgacac catcacctgc accaatcccc atgcagatgt tcccgcgaaa tgcacgcaga
     8521 acagcgccat tgagataaac gctacagcct gggctggcga ggaggattgc acgaccagca
     8581 acgtgcctaa tgccgacatc atcaaaccgc agacaatagc cgttttacgc gtcttcgcca
     8641 ggtcgtagcc ttttttcgcc agccgatcga caacaatacc gttaacccac atcccgaccg
     8701 ccgccgcgag gaaaggaatc cccgccacgc cgatgatgac gaacattgcc cgccagcccc
     8761 atgccagctg catcaataca agagcaggag gcgcaatagc ctgaccgata acggtagatg
     8821 agttaaaaat ccccagcgcc gtgccgcgtt ctttttgcgc ataccagtcg gtgatcgatt
     8881 ttactcccgc aggcataaat ggcgcttcgc caatacccag accgatacgc attaaaataa
     8941 agtggctaaa agaattaacc attcctgtta atgcctgcat taatgaccag aatattaagc
     9001 ctgcgcctaa aactattcgt gggccaaagc ggtctagcaa aataccggaa gggagttgtg
     9061 aaaaaccata agacagagaa aatgcagaaa gcaaaacgcc aaattctgtc gccgataatc
     9121 ctaactcgcc acgaatcgct tcgcctgcca cgctcaatga cgaacggtcg aggaaattaa
     9181 cgatccccgc cataaataat aaaaccagcg ttactgtctg aatacgacga atccgttgcg
     9241 gtttattacc cgcaacactg gttgacacat caacgtccat ttttagctcc ttgagcggaa
     9301 ttaatcgatt tgatgactat tcagaaaata attaagcgaa ctgttattac cagttccaca
     9361 atgtgccatc ttccagtcgt gcgacgggga gatacgccgg gtcatacgga tatttcgccg
     9421 ccagtttctc atcgaaagaa atacccagcc ccggttcatc gcctgggtgc atataacctt
     9481 catcgaagcg ccagctatgc gggaagactt caagcatttg ttcggaatag cccatgtact
     9541 cctgaacgcc aaagtttggc acccagaggt caaaatgcag cgccgccgca tgacaaacag
     9601 gcgataaatc tgaaggacca tgcgaaccgg tacgtacctg ataaagcgat gcaaaatcgg
     9661 caatccgtcg catcccggta atgccgcctg catgggtaat cgtcgtgcga atatagtcaa
     9721 tcagctgctc ttcgattaac tgcttgcagt cccagatact gttaaacact tcaccgaccg
     9781 caatcggcgt cacagtatgc tggcgaatca gacgaaaaca ttcctggttc tcagcaggcg
     9841 tcggatcttc catccagaac aggcggtaat cctcaatgct cttcccaaag cgcgccgctt
     9901 cgataggagt caggcgatgg tgcatgtcat gcaacagatg ttcgttaaaa ccgaacttat
     9961 tacgcaccgc ttcaaataac ttcggtgtaa aatcgagata cttttctgaa gaccacaact
    10021 gctcttccgg ccacaggcct ttggttgccg gttcatacgc cagtcctttg cccttcgcca
    10081 ggccataagt ggtttgcata cccggtacac cgcactgcac acgaatcgcc ttaaagccca
    10141 tctgctggtg ctttgcatag tcttcaagga cttcatcaat cgtgcgcccg gtggtgtggc
    10201 aataaaccat cacgccttca cgagaagcac caccaagcag ttgatacaat ggcatatttg
    10261 ccgctttggc tttgatatcc cacaacgcca tatcaatggc agaaatggcc gacatcgtga
    10321 cggggccacg tcgccagtaa gcacctttat aaaagaattg ccagatatct tcgatacggc
    10381 tggcatcgcg gccaattaat tgtggacaaa gatgatcttt cagataagaa gcgaccgaca
    10441 attcgcgacc atttaatgtg gcatctccca atccacaaag tccgcttgca gtggttattt
    10501 taagcgtaac gaaattacgt cctgggcaag taacaaaaac atctgcagca ataattttca
    10561 ttattgcaat ctcctgtgtt gtaaatagac gcttcaaact taattttaca cctactacca
    10621 tacaagagag aaggagcgat tattcaaccg tgatcacatt aaaaataaaa atttccgccg
    10681 aggagaaaaa acaccctcaa aaaccacctg aataattaac catcatcgtt aaaacaacac
    10741 gttaaataat cacataacaa actccattaa tcattaaaaa tgagcacagc aatagaaatt
    10801 aattatattc aattaattaa aacatgtatt gattgatgta ttgaaaatat gattttcatg
    10861 gggagagtga aggtaaagaa gacgcaagaa taaaaaggaa tatgacaaat aatagttctg
    10921 gttgggcgtt aaatttaagg tcaccagaat gctgacaaat ttctgcctga ggcagtccgc
    10981 ctacgtagtg tcgctacttt ataggcgtgg taagctcccc attttcaggg gagcaatata
    11041 aaccaattac tctaaccgag cctgcgcaaa agcaatcgcc tgcgccacct gctgcggtga
    11101 gacgccgcct tttgccgcac gcttgtcgag gcacgattgt agcgacagaa tcggatagac
    11161 atcttcgcca atcacctgac tgaatttctg caactcactg agcggtagtt cttccagcgg
    11221 tttgccctga cgaatggctt ccaccaccgc ttcaccaaca atatggtgcg cctcgcggaa
    11281 cggtacgcct ttcgccacca ggtaatccgc cagttcagtg gcgttggcgt aaccctgctg
    11341 cgccgcttcc tggcaacgcg gacgtttcac ctgaatgcca tccagcacca gcgccgccat
    11401 atgcaggcag tccagccagg tatcgagcgc gtcgaacaga ccttctttgt cttcctgcat
    11461 atctttgttg taagccagcg gcaaaccttt cagcgtcatc atcatgccgg ttaacgcccc
    11521 ctgcacccga ccgcatttac cgcgaatcag ctccagcgca tccgggtttt tcttctgcgg
    11581 cattaatgat gaaccggaag tcacacggtc agaaagctcg acaaaccccg cttcgccggt
    11641 gttaaagaaa atcagatctt cagcaaaacg cgacagatgc accatgccga tagcggcagc
    11701 agaaagcagt tccagcacgt ggtcacggtc agaaacgctg tcgagactgt tacgggtcgc
    11761 tgaagcaaag cccagccagc cagctaactg ttcacggtcg atttcataag ccgttcccgc
    11821 cagcgcgcca cagcctaacg gactgacatc cagacgctta agcgcatcct gcaagcggct
    11881 ttcatcacgc gccagcatct ccacgtaagc caggcaccag tgcgcgaacg tcaccggttg
    11941 agcacgttgc aggtgggtgt aacctggcat taccgcgtcc tgattgttct gcgcggtctc
    12001 gaccagagcg gattgtaact gccggttagc cgtcagcaac tcgctaacgg tatctttgca
    12061 ccacagtttc aggtcagtcg ctacctgatc attacggcta cgcccggtat gcagcttttt
    12121 gcctaactga cccactttgt cgatcagttt gctttccacc cagctatgga tatcttcggc
    12181 gtcgctttca aggatttgtt gtggcctggc gcgaacatct tccagcagca cgttcagcgc
    12241 ctcttccagt tgcgcctgct cttctgcggt taacacgccg accgttacca gggctttgga
    12301 ccaggccaca gagccaacaa tatcctgctc cgccagacgg taatcaaagc gcagtgagtc
    12361 gttgaattgt ttgaaccgtt gatctgctgc ctgggtaaaa cgcccgcccc aaagtgccat
    12421 aactctgttt ccttattttg aaattcaatg ccggaaagct gcgcctccgg ctaacaaaac
    12481 ttaagctaaa atccgcgtac ccatcggcat accgttaaac agtgccggaa gctgttccgc
    12541 atgacgccag gaggcgatat ctaccggacg gcccagcgtg cgcgcagcat ccagcgccgc
    12601 gttcactttc actatcatgc cgtcagtaat aatgccctgc tcaatcagtt gttctgcttt
    12661 cgcggcggtc atttcggcaa tacgttgccc tttgccgtcg agaatgccgc tgacgtcgga
    12721 gagcaaaatc agatccgcgc ccagcgttgc cgccagcgcc gttgccgcct gatcggcatt
    12781 gacgttcatc agttgccctt cgtctgttac gccaatggag ctgaccaccg gcagataacc
    12841 gttctccagc aaggagttga taagcttagg cgaacctggc tgcgccagtc caacatggcc
    12901 taactcttca tcaagctggg tcactttgac gctgtcgccg tcaccgagaa acaaacctac
    12961 ggacgcaatc tgatgtttct tcgcccatgc cagcagggtt ttatttgccg ttcccgccag
    13021 tgctccggtg ataatgttta tctgatccgc tggcgtcacc cgcaggccat ttttcttttt
    13081 caccggcaga ttcagccctt tcatcaactc atccactacg cagccgccac cgtggacaat
    13141 caccagcgga cgctgatgtg actcacgata attcaccagg gcgctaaaca gacgttccag
    13201 cgcctcttca ctatccagca gtacgccgcc cagtttgata attaatggat tcatcattgc
    13261 acccttaaat aagagactgc gtttccgcat agccgaaacg aatattggcg cactgtaccg
    13321 cttgtgccgc cgcgcctttc agtaagttgt cttcggtcgc cacaataatc agatgctcgc
    13381 cctgaacggc aaacccgata tcgcaaaatg gcagcccaac gacatttttc agcgccggaa
    13441 cgcctttgtc atacagccgc accagcggtt tatgggcata cgcctgctgt aacacttgcg
    13501 cgacttgcgc ctgggtcaca cccgatttca ggcggcaggt aatggtttcg agaatgccgc
    13561 gcgggaaatt gcccagatgc ggggtgaaga taacgtcagc accgaggtgt gtggcgatct
    13621 ctggttgatg acgatgggta aagacgccat acggttgcag gctaacttca caaaaactat
    13681 ttgaaatcgc tgccttacgt cctgcaccgc tcacgccgct ggtagcgttg atcaccggcc
    13741 actgaatgag gtcaagaaga tcggcatcaa tcaacggttt cagcgccagc tgtgctgccg
    13801 tcggataaca gcctggcacc gcaatcaagt tcgcttcttt taatttatta ccgcaccact
    13861 ccgccagacc gtaggctgcc tgttccagca gttccgggta ttgatgggta aagccgtaat
    13921 atttttcata gaaggcggcg tcgttaacac gaaacgcgcc ggaaaggtcg aacaccacgc
    13981 agccggcttc aagaaattgc ggcgctaaat cgtggctaac ttcatgggcg gtggcgagaa
    14041 acaccacgtc cacccctggg ctaaactcgc tgatatccga catcggctgc aacggcagat
    14101 caacgatgcc ttttagctgc ggatgcaaat cggagattaa ctttcccgca tcattgcttt
    14161 gcgctgaaac agtcaaagcg gttatgttca tatgcggatg gcgatttaca taggtcacta
    14221 gctctgcgcc agcgtagccg ctggcaccca caatcagcgt attcaacatc ggggctattc
    14281 accttcttat gtctggttgc caggttaaac gtaaaacatt caccttacgg ctggtgggtt
    14341 ttattacgct caacgttagt gtatttttat tcataaatac tgcatgaata ttgatactat
    14401 catgaccaga ggtgtgtcaa caatgaaaaa caaattaccg ccatttatcg agatttaccg
    14461 tgctctgatt gccacacctt caataagcgc cacggaagag gcactcgatc aaagcaatgc
    14521 agatttaatc actctgctgg cggactggtt taaagattta ggcttcaatg tggaagtgca
    14581 gcctgtgcca ggaactcgca acaaatttaa tatgctggca agtaccggac agggggctgg
    14641 cggtttgttg ctggcggggc ataccgatac ggtgccattt gatgacggac gctggacgcg
    14701 cgatccgttt acactgacgg agcatgacgg caagctttac ggcttaggca ccgccgacat
    14761 gaaaggcttt tttgcgttta tccttgatgc gctacgcgat gtcgacgtca cgaagcttgc
    14821 aaaaccgctc tacattctgg cgactgccga tgaagaaacc agtatggccg gagcgcgtta
    14881 ttttgccgaa actaccgccc tgcgcccgga ttgcgccatc attggcgagc caacgtcgct
    14941 gcaaccggta cgcgcgcata aaggtcacat ctcaaatgcc attcgaatta tgggccagtc
    15001 gggccactcc agcgatccag cacgcggagt taacgctatc gaactgatgc acgacgccat
    15061 cgggcatatt ttgcaattgc gcgataacct gaaagaacgc tatcactatg aagcgtttac
    15121 cgtgccatac cccacgctca acctcgggca tattcacggt ggcgacgctt ctaaccgtat
    15181 ttgtgcttgc tgtgagttgc atatggatat tcgtccgctg ccgggcatga cactcaatga
    15241 acttaatggc ctactcaacg atgcgctggc tccggtgagc gaacgctggc cgggtcgtct
    15301 gacggtcgac gagctgcatc caccgatccc tggctatgaa tgcccgccaa atcatcaact
    15361 ggttgaagtt gttgagaaat tgctaggagc aaagaccgaa gtggtgaatt actgtaccga
    15421 agcgccgttt attcaaacgt tatgcccgac gctggttctg ggccctggct caattaatca
    15481 ggctcatcaa cctgatgaat atctggaaac acggtttatc aagcccaccc gcgaactgat
    15541 cacccaggtg attcaccatt tttgctggca ttaaaacgta ggccaaacaa tgtcggatgc
    15601 gatgcttgcg catcttatcc gacctacacc tttggtgtta ctcgaggcga ttttttaaca
    15661 ttcccataag ttacgcttat ttaaagcgtc gtgaatttaa tggcgtaaat tcctgctatt
    15721 tattcgtttg ctgaagcgat ttcgcagcat ttgacgtcac cgcttttacg tggctttata
    15781 aaagacgacg aaaagcaaag cccgagcata ttcgcgccaa tgcgacgtga aggatacagg
    15841 gctatcaaac gataagatgg ggtgtctggg gtaatatgaa cgaacaatat tccgcattgc
    15901 gtagtaatgt cagtatgctc ggcaaagtgc tgggagaaac catcaaggat gcgttaggag
    15961 aacacattct tgaacgcgta gaaactatcc gtaagttgtc caaatcttca cgcgctggca
    16021 atgatgctaa ccgccaggag ttgctcacca ccttacaaaa tttgtcgaac gacgagctgc
    16081 tgcccgttgc gcgtgcgttt agtcaattcc tgaacctggc caacaccgcc gagcaatacc
    16141 acagcatttc gccgaaaggc gaagctgcca gcaacccgga agtgatcgcc cgcaccctgc
    16201 gtaaactgaa aaaccagccg gaactgagcg aagacaccat caaaaaagca gtggaatcgc
    16261 tgtcgctgga actggtcctc acggctcacc caaccgaaat tacccgtcgt acactgatcc
    16321 acaaaatggt ggaagtgaac gcctgcttaa aacagctcga taacaaagat atcgctgact
    16381 acgaacacaa ccagctgatg cgccgcctgc gccagttgat cgcccagtca tggcataccg
    16441 atgaaatccg taagctgcgt ccaagcccgg tagatgaagc caaatggggc tttgccgtag
    16501 tagaaaacag cctgtggcaa ggcgtaccga attacctgcg cgaactgaac gaacaactgg
    16561 aagagaatct cggctacaaa ctgcccgtcg aatttgttcc ggtccgtttt acctcgtgga
    16621 tgggcggtga ccgcgacggc aacccgaacg tcactgccga tatcacccgc cacgtcctgc
    16681 tgctcagtcg ctggaaagcc accgatctgt tcctgaaaga tattcaggtg ctggtttctg
    16741 aactgtcgat ggttgaagcg acccctgaac tgctggcgct ggttggcgaa gaaggtgccg
    16801 cagaaccgta tcgctatctg atgaaaaacc tgcgttctcg cctgatggcg acacaggcat
    16861 ggctggaagc gcgcctgaaa ggcgaagaac tgccaaaacc agaaggcctg ctgacacaaa
    16921 acgaagaact gtgggaaccg ctctacgctt gctaccagtc acttcaggcg tgtggcatgg
    16981 gtattatcgc caacggcgat ctgctcgaca ccctgcgccg cgtgaaatgt ttcggcgtac
    17041 cgctggtccg tattgatatc cgtcaggaga gcacccgcca taccgaagcg ctgggcgagc
    17101 tgacccgcta cctcggtatc ggcgactacg aaagctggtc agaggccgac aaacaggcgt
    17161 tcctgatccg cgaactgaac tccaaacgtc cgcttctgcc gcgcaactgg caaccaagcg
    17221 ccgaaacgcg cgaagtgctc gatacctgcc aggtgattgc cgaagcgccg caaggctcca
    17281 ttgccgccta cgtgatctcg atggcgaaaa cgccgtccga cgtgctggct gtccacctgc
    17341 tgctgaaaga agcgggtatc gggtttgcga tgccggttgc tccgctgttt gaaaccctcg
    17401 atgacctgaa caacgccaac gatgtcatga cccagctgct gaatatcgac tggtatcgcg
    17461 gcctgattca gggcaaacag atggtgatga ttggctattc cgactcagca aaagatgcgg
    17521 gggtgatggc agcttcctgg gcgcaatatc aggcacagga tgcattaatc aaaacctgcg
    17581 aaaaagcggg tattgagctg acgttgttcc acggtcgcgg cggttccatt ggtcgcggcg
    17641 gcgcacctgc ccatgcggcg ctgctgtcac aaccgccagg aagcctgaaa ggtggcctgc
    17701 gcgtgactga acagggcgag atgatccgct ttaaatatgg tctgccagaa atcaccgtca
    17761 gcagcctgtc gctgtacacc ggggcgattc tggaagccaa cctgctgcca ccacctgagc
    17821 cgaaagagag ctggcgtcgc attatggatg aactgtcagt catctcctgc gatctctacc
    17881 gtggctacgt acgtgaaaac aaagattttg tgccgtactt ccgctccgct acgccggaac
    17941 aagagctggg caaactgccg ttgggttcac gtccggcgaa acgtcgcccg accggcggcg
    18001 tcgagtcact gcgcgccatt ccgtggattt ttgcctggac acaaaaccgc ctgatgctcc
    18061 ccgcctggct gggtgcaggt acggcgctgc aaaaagtggt cgaagatggc aagcagagcg
    18121 aactggaagc catgtgccgc gattggccat tcttctcgac gcgtctcggc atgctggaga
    18181 tggtcttcgc caaagcagac ctgtggctgg cggaatacta tgatcaacgt ctggtagaca
    18241 aagcactgtg gccgttaggt aaagagttac gcaatctgca agaagaagac atcaaagtgg
    18301 tgctggcgat tgccaacgat tcccatctga tggccgatct gccgtggatt gcagagtcta
    18361 ttcagctacg gaatatttac accgacccgc tgaacgtatt gcaggccgag ttgctgcacc
    18421 gctcccgcca ggcagaaaaa gaaggccatg agccggatcc tcgcgtcgag caggcgttaa
    18481 tggtcactat tgccgggatt gcggcaggta tgcgtaatac cggctaatct tcctctcctg
    18541 caaaccctcg tgcttttgcg cgagggtttt ctgaaatact tctgttctaa caccttcgtt
    18601 ttcaatatat ttctgtctgc attttattca aattctgaat acaccttcag atatccttaa
    18661 ggaattgtcg ttacattcgg cgatattttt ttcaagacag gttcttacta tgcattccac
    18721 agaagtccag gctaaacccc tttttagctg gaaagccttg ggttgggcac tgctctactt
    18781 ttggtttttc tctactctgc tacaggccat tatttacatc agtggttata gtggcactaa
    18841 cggcattcgc gactcgctgt tattcagttc gctgtggttg atcccggcat tcctctttcc
    18901 gaagcggatt aaaattattg ccgcagtgat cggcgtggtg ctatgggcgg cctctctggc
    18961 ggcgctgtgc tactacgtca tctacggtca ggagttctcg cagagcgttc tgtttgtgat
    19021 gtttgaaacc aacaccaacg aagccagcga gtatttaagc cagtatttca gcctgaaaat
    19081 tgtgcttatc gcgctggcct atacggcggt ggcagttctg ctgtggacac gcctgcgccc
    19141 ggtctatatt ccaaagccgt ggcgttatgt tgtctctttt gccctacttt atggcttgat
    19201 tctgcatccg atcgccatga atacgtttat caaaaacaag ccatttgaga aagcgttgga
    19261 taacctggca tcgcgtatgg agcctgccgc accgtggcaa ttcctgaccg gctattatca
    19321 gtatcgtcag caactaaact cgctaacaaa gctactgaat gaaaataatg ccttgccgcc
    19381 gctggcgaat ttcaaagatg aatcgggtaa cgaaccgcgc actttagtgc tggtgattgg
    19441 cgagtcgacc cagcgtggcc gcatgagtct gtacggttat ccgcgtgaaa ccacgccgga
    19501 gctggatgca ctgcataaaa ccgatccgaa tctgaccgtg tttaataacg tggttacgtc
    19561 tcgtccgtac accattgaaa tcctgcaaca ggcgctgacc tttgccaatg aaaagaaccc
    19621 ggacctgtac ctgacacagc cgtcgctgat gaacatgatg aaacaggcgg ggtataaaac
    19681 cttctggatc accaaccagc agacgatgac cgcccgcaat accatgctga cggtattttc
    19741 gcgccagacc gacaagcagt actacatgaa ccagcaacgt acgcagagtg cgcgtgaata
    19801 cgacaccaac gtgctgaagc cgttccagga agtgctgaag gacccggcac cgaagaaact
    19861 gatcatcgtt catctgctgg gtacgcatat caaatacaaa taccgctacc cggaaaatca
    19921 gggcaagttt gatggcaata ccgatcatgt cccgccgggg ttaaacgcgg aagagctgga
    19981 gtcatataac gattatgaca acgctaacct gtataacgat catgtggttg ccagcctgat
    20041 taaagacttt aaagcggcag acccgaacgg attcctggtt tacttctctg accacggtga
    20101 agaggtttac gacacgccgc cgcataaaac ccaggggcgt aatgaggaca acccgacgcg
    20161 tcatatgtac accattccgt tcctgctgtg gacgtcagaa aaatggcaag cgactcatcc
    20221 gcgtgatttc tcgcaggatg ttgatcgtaa atacagcctt gcggaactga tccacacctg
    20281 gtcagatttg gcgggcttat cttacgacgg ttacgatcca acccgttcag tggtgaaccc
    20341 gcagttcaaa gaaaccaccc gctggattgg taatccgtac aagaaaaatg cgctgatcga
    20401 ttacgacact ctgccgtatg gcgatcaggt aggtaatcag taaatgacct ttgtatcgcg
    20461 tctggcgcta tttgccggat gcgatactgc cgcaatgttt acatcgcact cccctcaggc
    20521 cacacttttc aggtggcctt ttttcataat gccagttact gttttcccgt ctacatagct
    20581 aagggaataa catgtatcac gacgtcagct atctgctctc ccgcctgatc aacggcccgc
    20641 tgtccctgcg ccagatttac tttgccagca gcaacggccc ggtgcccgat cttgcgtatc
    20701 aggtcgattt tccacgactg gaaattgtgc tggaaggtga gtttgttgat accggcgctg
    20761 gagcaacgtt agttcccggc gatgtgctgt acgttcccgc tggtggctgg aattttccac
    20821 aatggcaagc ccccgccacg acctttagcg tgctgtttgg caaacagcaa ctcggcttca
    20881 gcgtcgtgca atgggatggc aaacaatatc aaaatctggc gaagcaacac gtcgcccgac
    20941 gcggcccacg cataggttct tttctgctac aaacgctcaa tgaaatgcaa atgcagtcgc
    21001 aggagcagca aacggcaagg cttatcgtcg ccagcctgct tagccactgc cgcgatttgc
    21061 tcggcagcca aatccagacc gcctcacgta gccaggctct attcgaagct attcgcgatt
    21121 atatcgacga acgctatgcc tccgcgctta cccgcgaatc tgtcgcacag gcattctata
    21181 tttcgccaaa ttacctctcg cacctgtttc aaaaaacggg ggccattggt tttaacgaat
    21241 acctgaatca cacgcgactg gagcacgcta agacgttatt gaaaggctat gacctgaagg
    21301 taaaagaagt ggcgcacgcc tgcggctttg tcgacagcaa ctacttctgc cgtctgtttc
    21361 gtaaaaatac cgaacgctca ccgtcggaat atcgtcggca gtaccacagc caactgacag
    21421 aaaaaccgac tactccagaa taagatggat ttgctgcggc gcagaaagca ctttgcgtac
    21481 cgcgctcatc acccgctgcg gctcacgcag gaaagcgtag atgctgcatt gcacgtagcg
    21541 gcaatgttca aatcgctcgg caccggcaag ctcgatatcc gtaatcaaca gagcaacatc
    21601 cgcccgacgg atatcctcgt ccgctaaacg attctccgtt cccagcgcgc cctgagtttc
    21661 aatgctgacg ccccacttct ctaactggca caacttttcc agccgttccg ccgccatata
    21721 agtatgcgcc acgccgctta cgcaggcggt tactgccacc aggtatgcca ttttaacctc
    21781 ccacggtaac ctgaaatccg gcccgttctg ccatttcgcg catcgttgtc acatcggctg
    21841 acgacggcgc agacacctct ttcatcgacc atgttttccc cagcaggcgg tatttcggtt
    21901 cgccgtactg atgaaacggt aacagatgga tctgcctgat attcagcggg atcagcacgt
    21961 ccagcgcctg ctgcatattc tcccggctga gcgtgaaacc agggatcagc ggtaaacgcg
    22021 ggatcacgtt gacgccctca ctcaccagca aacgcagatt ctccagcacg cgtggcaggt
    22081 tcatcttcac cacatcccgc gcctgagtcg cgtccataat ttttaaatcg aacaacactt
    22141 catcgcacaa tttcgccagc ggtaacagct tgctggctgg cgcgtctccg gcggtttcaa
    22201 tggcgcatga cacgccccac aaccgcagcc gctgtaaaaa acgggtagca aactccgcct
    22261 gcattaacac ttcgccgcca gaaagcgtga cgccgccgcc ggacgtgcga aagaaaatgt
    22321 catctttcat cacttcccgt tccagagcgt caaggctgat atcgcgacca atccgttcaa
    22381 acgcaccgga ggggcattca tccgcatcac gcaaacattt cgcacagtgc agacatttcg
    22441 cctctctgcg tacagtctgg attttgccgg agatcgactc cggattagca caccacgggc
    22501 aaagatgcgg acagccttta aaaaagacca ccgtacgaat gccctcgccg tcattcagtg
    22561 aataacgctg aatgttgaaa atgcgcgcca catcatcgcg gcgcgtttcc acaacgttac
    22621 agctgatgcg ctgtccggcg gatgatgtca tcctggatct ccttcgacaa ttcgacaaag
    22681 aaggcgctgt atccggcaac gcgcaccacc agcccggcat aatcttgtgg gcgctgttgc
    22741 gcttcccgca acgtgtcggc gttcaccacg ttaaactgaa tatgctgcaa cttaagctgg
    22801 gtaaacgccc gtaagaagtc ggccagtttg cgtaatcccg cttcaccttc cagggtcgcc
    22861 ggagtgaatt tcacgttcag caacgtaccg ttagacagca gcgtattatc gagcttactg
    22921 actgacttca gtaccgccgt tggcccttgt gcgtcctggc ccagcatggg tgacaagccg
    22981 ccgtctgcca gctgttctcc ggcaaaacga ccgtctggcg tcgcgccaac caccgatccc
    23041 aacgggacgt gagcagaaac ggtatacgat cccggcgtga agtaaccgcc gcgcgggttc
    23101 tggtattttt ccacttcttt gcagtagtgg cgcaacagtt cggcgctgat gttatccacc
    23161 tcgtcgatat cgttaccgta tttctcgaag cggttaatta agcgagcacg gactttttcg
    23221 ccttctggcg ttgcgaagtt ggcttttaat accgacagca attcgtcaaa acttaaacgc
    23281 tgttgctcaa aaaccatacc tttcaacgca tggagagaat cgctcaggtt ggcgataccg
    23341 atcccctgta cgccggagaa gttataacgc gcaccgccat cggtaatatc gcggcctttt
    23401 tccagacaat cgctgataaa agacgagagt agcggtacag gtgcccagtc gcgatggccg
    23461 atatcacaaa tattgctgcc ctcaaccatc agggtgatgt agtggctgat cttggcgcgg
    23521 atctgctcca gtaaaccttc ataagtcagc gcagcattgc cttcattttc atgcaggcag
    23581 atttccatca ctttcagcaa gttaaacatc gcaatgtcat gcagaccgta ggttctgccg
    23641 ggaatagata attccacaca gcccactacg gaatagtcgc gcgcatcttc cagcgaaacg
    23701 ccacggttga ggaacgctgg cactaccact tcatcgttaa agatttgcgg aataccggtg
    23761 ccgaggcgaa tggtttctgc ggttttcatc aggaacggcg tgtcgatcaa ggcgttagtg
    23821 cgcacgccga ggttcggttg cggtaattgc acgctttgat aagcatcgag gcagaggaac
    23881 gaaagcacgt tcaccgcgct acgtccattc tcggttaaac cgccgagcag tgcggtatag
    23941 ccggtcggga aaccggcgaa ataacgcgcg ctgctggtgg agcgcaacag cacgatgtcg
    24001 ttgcatttca cccataaaga ttcgagcagt tctttcagga acgccggatc ttcgcccagg
    24061 gttaaagatg cctgatagaa cggcaacata tactggtcga agcgccctaa agacagcgaa
    24121 ctggcgttgg attcgtattg cagaatgatg ttcatgtacc agaataactg gcacgcctgc
    24181 cagaacgtct gcggcttatg ttgcgcgtta tggcgggaga tctccgcaat agtcagcagc
    24241 tcttcgcgac gctgggcatc tgtgcagttt gccgccatcg tttccgccag ttcggcgtaa
    24301 cgcaaaatgt gtttctgcga ggcttccagc agtaacaacg cggcctgata aaagtgattc
    24361 tccggctgtt gctgacaatg ttgctgcatt tgcgctacca gctcacccag cccgtgattc
    24421 agcaggcgcg ggtaatcaat aataatgtgc ccctggcctt tatccgtctg gttgatgctg
    24481 aaaatctgcg tgctggtcgc ggcttttact tcatccgtca tctgcccgtt aatgaaatct
    24541 ttcatcgaac gtttttccca gtacgggaac aactcttcgc ggtagatacg tttatcttct
    24601 tcgctgatag caaagcggtc ctgcggacgc gtcgggaatt gatccagctc tttcagcagc
    24661 cagtaagggt ccatttccgg cgacataatc ccggcgcgtg gttttacggt gcggttaccg
    24721 gcaatcagtt cttcatcacg aatcgaaatt tcaacatgtt caaggatata cgctgttgct
    24781 ttcgcccggc gcaatatcac cggttcgcct tcggtttgcc gatggctggc ggtataaagc
    24841 agcgcccgct ccagcgagat ttcacgggta ttggcaaaca gtgcagtttt gaggcgagag
    24901 atacgattcg tcatgaggaa ctcctgtggg aaagcgaacc cgcccttacg ggcgggataa
    24961 gaacttaagc ggtttgtgcc aggtgagctt caattttgct cataatggca tcagcgcgtt
    25021 ttaccgcgtc gctgatgttg acgcgcacga tggtcttgcc agcaaaacgc tcttcaaact
    25081 tgatgccgat atctttggtc agaatcacca tatcggcgct cgccacgtct tccgcagtca
    25141 gttcattttc cagaccaatc gagccctggg tttctacttt cacttcccag cctttcgctt
    25201 tcgcggcact ttccagcgcc tctgccgcca tataggtatg ggcaacacca gatggacacg
    25261 cggttactgc aataattttc gtcatggctc gttcctcaat taattaattt caaaatccaa
    25321 atccaggtcg tcttcttttt catcagtcga agacccattt ttacgcgcca gacttttcag
    25381 cacgttcaca caaacagccg tcaccactgc tccgacagcc actgctgcga tataacccag
    25441 cttgccttca accaccggca gcacaatcag accaccccag cctgcatagc actgtgcacc
    25501 gaccagtgcc gcagttaccg caccacaaac agaaccgacc atgatggaag gaatgacacg
    25561 taacggatcg gcagcggcga aaggaatcgc cccttcagta accccaacgc accccatcac
    25621 cagcgccgct ttgccggttt cgcgctcttc tgcggagaaa tttttacgac caatcagcgt
    25681 cgccaacccc atccccagcg gcgggataca aatacccacg gcagcaatgg ccaccacggt
    25741 atatacaccc tgagcaacgc aaatcagcat gaaggcatag gccactttgt taaccggacc
    25801 acccatatcg aacgccagca tcagacccat gatcaccgcc agcataacaa tgctgccctg
    25861 ctgcatcccc tgaagccact gagtcaggct gttggtcaac gcccctacag gctcgcccag
    25921 accccacatc atgatgcctg cggtaatcag tgtgccgacg atcggaatga tgaagatggg
    25981 catcaccgag cgcagaactt tatgcaccgg aattttcttc aggtaatgca ccacgatgcc
    26041 gccgataatc ccggcgatca gtgcaccaaa gaagcccgca ccaaagctgt taccaaccca
    26101 ggcaccgata gcgcacggag ccagcgcaga acgctctgca atggaataac cgatgtaagc
    26161 ggcgaggaaa ggcaccatca gcgtcaaacc tgcaacgccg atatcaaaca gttttttcag
    26221 attcggatcg gcgacggcat ccggcactgc gcctttgcca tacaacatga cggaaaccgc
    26281 cagcaaaata ccgcccgata ccacgaaggg aatcatgtgt gaaacgcccg tcattaaatg
    26341 ctgacgagta tttttcagga tctgcaccaa ctcattcata agctgctccc gggcttgcga
    26401 aagcccatgt ccatattttt gatggaagaa acaataggca atcgcaggcg gagcaaacag
    26461 tggataaaaa ggccatttac tggacttttg taatatcagt acaaaaatgc gatccgcctc
    26521 ataacttgcg ataatccgga agtacaccgc aaaacggcgt cttgtgagac gcgtcgcaaa
    26581 ttgacggtta cattacattt gtccagcttt tggcagattt gtcacatggt aggccgttgc
    26641 cgtgcgctct tatcctgtaa acagaaaacc gtaccgggag aaaggcaatg gccctgattg
    26701 tggaatttat ttgtgagcta cctaacggcg tccatgcgcg tccggcaagc cacgttgaaa
    26761 cgctgtgtaa tactttttca tcacaaattg agtggcataa cctgcgcact gaccgcaagg
    26821 gcaacgccaa aagcgccctt gcgctgattg gcaccgatac gctggtgggc gataactgcc
    26881 agttactgat ttccggggcc gacgaacagg aagcgcacca gcgtttaagc caatggctgc
    26941 gcgatgaatt cccccactgc gacgcaccgc tggcggaagt aaaatctgac gaactggaac
    27001 cactgccggt ttcactgacc aatctgaatc cgcaaattat ccgtgcccgc accgtgtgca
    27061 gcggtagcgc aggcggcatt ctgacgccga tctcttcttt agatctcaat gcgctgggta
    27121 atcttcccgc agccaaaggc gttgacgccg aacaatccgc actggaaaac ggtctgacgc
    27181 tggtactgaa aaacatagag tttcgtctgc tggatagcga cggtgctacc agcgcgattc
    27241 tggaagcgca ccgatccctg gctggcgata cttccctgcg cgaacattta ctggcaggtg
    27301 tcagcgccgg attaagctgt gccgaagcga ttgttgccag tgcacaccac ttctgcgaag
    27361 agttcgcccg ttccagcagc agctacctgc aagaacgtgc cctggacgta cgcgacgtct
    27421 gcttccagtt actccagcaa atctacggtg agcaacgctt cccggcaccg ggcaaactga
    27481 cgcagcccgc catttgtatg gctgatgaac tgacccccag ccagttcctc gaactggata
    27541 aaaatcacct caaaggattg ttgctcaaaa gcggcggcac cacctcacat acggtgatcc
    27601 ttgcccgttc gttcaacatt ccgacgctgg ttggtgtgga tattgatgcc ctcactccgt
    27661 ggcagcatca aacgatttat atcgacggca acgcaggggc gattgtggtt gagccagggg
    27721 aatccgtggc ccgttattat cagcaagaag cccgcgtaca ggacgctctg cgtgagcaac
    27781 agcgtgtctg gctgacccaa caagcccgta ctgctgacgg tatccgcatt gaaattgctg
    27841 ctaacatcgc tcactccgtg gaagcgcagg ccgcattcgg caatggtgcg gaaggcgttg
    27901 gtttattccg cactgaaatg ctctatatgg atcgcaccag tgcaccgggc gaaagcgagc
    27961 tgtacaacat tttttgtcag gcgctggagt ccgccaacgg acgcagcatt attgtgcgca
    28021 ctatggatat tggcggtgac aaacccgttg attatctgaa cattcccgca gaggcaaacc
    28081 cgttcctcgg ttatcgcgcc gtgcgtattt atgaagagta cgcgtcgtta tttaccacac
    28141 aactacggtc gattctccgt gcctccgctc acggcagcct gaaaattatg atcccgatga
    28201 tctcttcaat ggaagagatc ttatgggtaa aagaaaaact ggcggaagcc aaacagcaac
    28261 tgcgtaacga acacattccg tttgatgaga agatccagct cggcatcatg ctggaagtgc
    28321 cgtcggtgat gttcatcatc gatcaatgct gcgaagagat tgatttcttt agtatcggta
    28381 gtaatgacct gacgcaatat ctgctagcag tggatcgcga taacgctaag gttactcgtc
    28441 actataacag cctgaatcca gcattcttgc gggcgctcga ttacgccgtg caggcggtgc
    28501 atcgccaggg caaatggatt ggtctgtgcg gtgaactggg agcgaaaggt tccgtgctgc
    28561 cattgctggt cggtttaggg ctggatgagc tgagcatgag cgcaccgtca attccggcgg
    28621 cgaaagcgcg aatggcgcaa cttgatagcc gtgagtgccg ccagttgctc aaccaggcaa
    28681 tggcctgccg tacttcgcta gaagtggaac acctgctggc gcaattccgc atgacccaac
    28741 aggacgcccc gctggtcacc gccgagtgca tcacactgga aagcgactgg cgcagcaaag
    28801 aagaagtgct caaaggcatg accgataacc tgctgctggc gggccgctgt cgctatccgc
    28861 gtaaactgga agccgacttg tgggcgcgcg aggccgtttt ctctaccggt ctgggcttta
    28921 gttttgccat tccccacagc aaatcagaac acattgagca atccaccatc agcgtggcgc
    28981 gtctggcagc gccggtgcgc tggggcgatg atgaagcgca attcatcatt atgttaaccc
    29041 tgaacaaaca cgctgcgggc gatcagcaca tgcgcatttt ctcgcgcctc gctcgtcgca
    29101 tcatgcacga agaattccgt aacgcgctgg ttaacgccgc ctctgccgac gctatcgcca
    29161 gcctgctgca acatgaactg gaactgtaaa aggaaacatc atggaactgt atctggacac
    29221 cgctaacgtc gcagaagtcg aacgtctggc acgcatattc ccgattgccg gggtgacaac
    29281 taacccgagc attatcgcgg ccagcaagga gtccatctgg gaagtgctgc cgcgtttgca
    29341 aaaagcgatt ggtgatgagg gtattttgtt tgctcagacc atgagtcgtg acgcgcaggg
    29401 tatggtggaa gaagcgaagc gcctgcgcga cgccattccg ggcattgtgg tgaaaatccc
    29461 ggtaacttcc gaaggtcttg ccgccattaa aatgctgaaa aaagagggta ttactacact
    29521 tggcaccgct gtatatagcg ccgcacaagg gttattagcc gcgctggcag gggcaaaata
    29581 tgttgctccg tatgttaacc gcgtcgacgc ccagggcggg gacggcattc gtacggttca
    29641 ggagctgcaa gcgctgttgg aaatgcacgc gccagaaagc atggtgctgg cagccagctt
    29701 taaaacgccg cgtcaggcgc tggactgttt actggcagga tgtgaatcca tcaccctgcc
    29761 cttagatgta gcgcaacaaa tgctcaacac ccctgcggta gagtcagcta tagagaagtt
    29821 cgaaaacgac tggaatgccg catttggcac tactcatctc taaaggagca attatggacc
    29881 gcattattca atcaccgggt aaatacatcc agggcgctga tgtgattaat cgtctgggcg
    29941 aatacctgaa gccgctggca gaacgctggt tagtggtggg tgacaaattt gttttaggtt
    30001 ttgctcaatc cactgtcgag aaaagtttta aagatgctgg actggtagta gaaattgcgc
    30061 cgtttggcgg tgaatgttcg caaaatgaga tcgaccgtct gcgtggcatc gcggagactg
    30121 cgcagtgtgg cgcaattctc ggtatcggtg gcggaaaaac cctcgatact gccaaagcac
    30181 tggcacattt catgggtgtt ccggtagcga tcgcaccgac tatcgcctct accgatgcac
    30241 catgcagcgc attgtctgtt atctacaccg atgagggtga gtttgaccgc tatctgctgt
    30301 tgccaaataa cccgaatatg gtcattgtcg acaccaaaat cgtcgctggc gcacctgcac
    30361 gtctgttagc ggcgggtatc ggcgatgcgc tggcaacctg gtttgaagcg cgtgcttgct
    30421 ctcgtagcgg cgcgaccacc atggcgggcg gcaagtgcac ccaggcggcg ctggcactgg
    30481 cagaactgtg ctacaacact ctgctggaag aaggcgaaaa agcgatgctt gccgccgaac
    30541 agcatgtagt gactccggcg ctggaacgcg tgattgaagc gaacacctat ttgagcggtg
    30601 ttggttttga aagcggcggg ctggcggcgg cacacgcggt acataacggc ctgaccgcta
    30661 tcccggacgc gcatcactat tatcatggtg aaaaagtggc attcggtacg ctgacgcagc
    30721 tggttctgga aaacgcgccg gtggaggaaa tcgaaaccgt agctgcgctt agccatgcgg
    30781 taggtttgcc aataacgctc gctcaactgg atattaaaga agatgtcccg gcgaaaatgc
    30841 gaattgtggc agaagcggca tgtgcagaag gtgaaaccat tcacaacatg ccaggcggtg
    30901 caacgccaga tcaggtttac gccgcactgc tggtagccga ccagtatggc cagcgtttcc
    30961 tgcaagaatg ggaataacct actccaaact cccggcttgt ccgggagttt gagagtgcag
    31021 gcaaagtggc tcactcgtca ctgcgggcat gtttttcccc ctcgcccttt cagggagagg
    31081 gtcggggtga gggtaaatat tcgccccgga gctggcctgt tcccctcacc ctaaccctct
    31141 ccccaaaggg gagagggggc tgttcgagca ctttttatac gttatcaccc gtctgaaact
    31201 cccacgttgt tcaggaattt tttatccgct tctggacatt ttctctacag aacaatcgtt
    31261 agcccggaag gtcgaatctg tgactcttat tttcacggac gaaccagatg aaagcttcac
    31321 tggtgctggt cagcctgcta acggcattta ccagccactc cttaaaatct cccgccgttc
    31381 caccaaccgt ggtacagatc caggccaaca ccaaccttgc catcgcagac ggtgccagac
    31441 agcaaatcgg cagcacgcta ttttacgatc cggcgtatgt gcagcttacc tatcctggcg
    31501 gtgatgtccc gcaagaacgc ggcgtatgtt ccgatgtggt gatccgtgca ttgcgcagcc
    31561 agaaggtcga tttgcagaaa ctggtgcacg aagatatggc gaagaatttt gctgcgtacc
    31621 cgcaaaaatg gcagttaaag cgcccggaca gcaacatcga tcaccgtcgg gtgcctaatc
    31681 tggaaacctg gtttacccgc cacgataaaa cacgccccac cagcaagaac cccagtgact
    31741 atcaatcggg cgatattgtc tcctggcgat tagataacgg gctggcacat attggggtgg
    31801 tgtcagatgg cttcgcccgc gacggtacgc cgctggtgat acataacatt ggcgcaggcg
    31861 cgcaggaaga agacgtgctg tttagctggc ggatggtggg gcactatcgg tattttgtta
    31921 aataagcgat cgccccacat gaagaaaaaa ttcagatgtt ttttacactg acagcttctt
    31981 ttttcttacg gctcaccagc gccagtgcca gcacaatcag cacaataccg ctaccttcaa
    32041 cggcccccgg attctcaccg agcagccacc aggaaaagag tacgccgcaa acgggaacgg
    32101 ccagtgtgct taagctggca atactggcag gcaagttttt caatacaaac aaccataagc
    32161 tccacgccag cgctgtcgcc agaatcgcac tgtaggccag cgcccagaac acggtgggtt
    32221 gccagtcaat ttcacgttgc ggcaccagta aagcgaccac gctcatcacc agcgccgcat
    32281 acagcatctg ccaggatgtt agcgacaata aatccacgcg cggatggcgg gcatacagac
    32341 gtttagcaac aatcgcgctc gccccccaac tcacaccgga gaggattgcc agcatggcgc
    32401 ttttcatcga agagaaatcg agttgccacg gctgcaacac caaaaataag ccgaaagcgg
    32461 caatcagaat cgcgaaatat tgcccacgtc gcaggcgttc accgagaaac aacgcggcga
    32521 aaatcaccac ccagaacggc atggtatagc tcaggattgc caccttcccc gctcctccgc
    32581 tgaccagcgc ccactgcgcc aggccgacca tcccgcaggt ttgtaacagg gcaatggcta
    32641 aggtgtattt aaacggtgtc gggcgcattc cgcgaccacg taataaaagg acgatgaata
    32701 aaacgagagc gccgaaaatg cagcgtaagg cggtaaagtc gaaggcaccg atgtagctgg
    32761 tgacttgctt catgaaaatc cagctataac tccagataag tgtgagcaca accaggccac
    32821 tgattgccag tgggttgctc tttcctgcgg cagacatgag agatccagtg tgtagttttc
    32881 ctgtggacac tatacgccgg taaagaaact tcagcgactg cctgaaaggc agtcgctgaa
    32941 gaaggtcaga ttacagcagg tcgaaacggt cgaggttcat cactttcacc cacgctgcca
    33001 cgaagtcttt aacaaacttc tcgtgggcat cgctgctggc gtaaacttcc gccaccgcac
    33061 gcaggacaga gttagaacca aagaccagat ccgcacggct ggctgtgtat ttcacttcgc
    33121 cggtttcgcg gtcacggcct tcgaacagct ctttcgattc gtcggtcgct ttccactcgt
    33181 aacgcatatc cagcaagttc acgaagaagt cattgctcaa tacgccaacg cggtcagtga
    33241 agacgccgtt tttgctgcca tcgaagttgg cacccagtac gcgcatcccg cccaccagcg
    33301 cagtcatttc cggcgcggtc agggtcagtt gctgggcttt atcaatcagc agtgactcgg
    33361 tggtggaaac gtccagacga gcgcgatagt tacggaaacc gtcagcaatt ggctccagca
    33421 gttcgaacat ctcaatgtca gtctgatcct gacgcgcatc aacgcgaccc ggcgcaaacg
    33481 gtacatgaat gctcaaacct gcggcgcttg cggctttctc aacaccaacc acaccagcca
    33541 gcacgatgat atctgccagc gaggctttac cagactcttt ctgaattttc tccagaactg
    33601 gcagagcacg aacggctgcg gcgttcacat cccagtcgcg ctgcggcatt aatgccagac
    33661 gtgcaccatt ggcaccacca cgtttgtcgc caccacggaa ggtagaagca gacgcccagg
    33721 ccaccgatac cagctcgctg acagacagac cagaatccgc aatcgcgaat ttcagatcga
    33781 taatgtcctg ctcggtcggg ttgtagatcg gctgcggcag cggatcttgc cagatcagat
    33841 cttctttcgg tacttccggc ccgatgtagc gagatttcgg ccccatatcc ctgtgcgtca
    33901 gtttgaacca ggcacgggca aaggcttcgt tgaacgcctg cggatcgttg aggaaacgac
    33961 gagaaatctt ctcgaactca ggatcaaaac gcagcgtcag gtcggtcacc agcattgtcg
    34021 gtttacgttt cttcgacgga tcgaacggat ccgggataat ttccggtgcg tctaccgctt
    34081 caaactggat tgcgccagcc gggctgcggg tctgtaccca ctcatacttg aacaggtttt
    34141 cgaagaagta gttgctccac tgggtcggcg tctgggtcca gactacttcc agaccagagg
    34201 taatggcatc tgcgccaacg ccgctgccgt aagtgctcgc ccagcctaaa ccttgttctt
    34261 caatcggtgc agcttctgga tcaggaccta catttgatgt cggaccggca ccgtgagttt
    34321 tacccagcgt atgaccaccc gcaatcagcg ccacggtttc ttcgtcgttc atgcccatgt
    34381 tgccgaaggt cgcgcggata gctgctgccg cagaaagcgg ttcgccgctg tgatccgggc
    34441 cttctgggtt aacgtaaatc aggcccatct cggttgcgcc cagcggtgct ttcgccagcg
    34501 cttccggatg acggtgggtc agccaggctt tttcatcacc ccagttaaca tccagatccg
    34561 gttcccagac atcttcacga ccggcaccaa aaccgaaggt acggaagccg gagttttcca
    34621 gcgccacgtt acccgcgagg ataaacaggt cggcccagga gattttctga ccatatttct
    34681 gtttgattgg ccacagcagg cgacgcgctt tatcgaggct tacgttatcc ggccaggagt
    34741 tcagcggtgc aaaacgttgc tgaccacgac ccgcgccgcc gcgtccgtcg atggaacggt
    34801 aagtacccgc gccgtgccag gccatacgaa taaacagacc ggcatagctg ccccagtcgg
    34861 caggccacca cggctgagat tctgtcagca gggctttcag atcttttttc aggccgtagt
    34921 aatctaattt gctgaattct ttgcggtagt caaagtcctc acccagcggg ttagaacgat
    34981 tagaatgttg gtttaacagg tcaacacgga gttgatttgg ccaccagtcg cgcgtggttg
    35041 tgcccccacc cgcgctctgg tcgtgaccgc cctgatggaa cgggcatttg ccagtggctg
    35101 tcgtgttatg gatatcgtct gacgtgctca tcaatgtgct cccctctaca gtgttaccgt
    35161 tacgatacac agcgttagag agaagttata attgaattaa tccacggatg cgatagttga
    35221 gatcttacat attgttggtt aaagagatgt agatcaaatt gatcgtaatt aagctttttt
    35281 gattatgtcc gaattcggac aaatgcttta taaaaaaggg ttttagcttc atatccgtca
    35341 agtaatgagg gagaaaacaa ggctgacaac cttattttcc cgccctcatt tcgaggcagc
    35401 attttgtgct ctgtttaaaa tttgtgatca ctgtgtgatt ttcacaaaag ccacactatt
    35461 tataaaccag gtcgaacacc cagcgtatgg caaatcgcgt aactcatttc agcacggtta
    35521 agcgtataga agtggaaatc tttcactcct tcacggctta aaatcttcac catatccatg
    35581 gcgatattcg cgcccaccag cttgcgggtt tcggcatcat catcaagccc gtcgaacatt
    35641 tgtgccatcc acgccggaat acgcacattg gtcatgtcgg caaatttctt cgcctgttta
    35701 aagttagata ccggcaaaat gcccggaatg atttccacat caatgcctgc cgatacgcag
    35761 cggtcacgaa aacgcaggta gctttcgaca tcaaagaaga actgagtaat cgcgcggttg
    35821 gctccggcat cgactttgcg tttcaggttg agcaaatccg cctgagcgct ttttgcttcc
    35881 gggtgaacct ccggatacgc cgccacggag atatcgaaat ctgccacttc ttttaacagc
    35941 gtcaccaggt cagaagcata catttccggc ttaccgcttc ccggcggcag atcgccacgc
    36001 agcgccacga tatgacgaat accgttattc cagtagtcac gtgcaatggt gcgcagctcg
    36061 tcgggcgtcg catcaatgca agtaagatgc ggtgccgctt ccagaccagt gcgatcttta
    36121 atgcctttaa taatgctgtg cgtacggtca cgctcgccgg agttcgcgcc ataggtcacc
    36181 gacacaaact tcggtttcag gttgctaagg cgatcgatgg agttccacag ggtctgctcc
    36241 atttcactgg tacgcggcgg gaaaaactcg aacgaaacgt taatctgccc ctggacttct
    36301 gccagactct gattcagggc atcccgctgg ctggcgtgaa aaaagctcat accttacctc
    36361 atcaatcgct tgtagttata tgttgtgttg tgaacatcta tccatttaga cgtccagatg
    36421 taaagatgaa ggaaaagccg aggggcgtca accgaaaaat gaccaatgat ggtgaggaaa
    36481 aatcagggaa gttgaaaaaa actcatctta attagaggcg ataaaagatt tctctatagc
    36541 gcaatccacc tcgcacgttt tgactgatat tctgacaaca cagcgacacc tgggcttatt
    36601 cgaaaaacaa cgtcctgcca ccggatggtg atgctaaggc atctgattcg gcctgcgccc
    36661 tcgcgtaggc cgaatactgg atctgcaaaa tcaacgggta acaaacaaat gaatcaactc
    36721 aatacgtact tttacttgat atctttcacg cgcataccgt tgatctgttc atccgtgatg
    36781 gtgttacccg ctttgaagta atcaaccacg gcgtgataaa cgtaataacc gcccgttgtg
    36841 ttacgcgctt tcccttcggt aaaggcggta aaaccatctc caccatcagc aaggaaactc
    36901 tgggtggcaa tagaataaac tgtcgcatct tcaatgggtt tgccattcag agtcagtgtg
    36961 attacccgct gaccaaccgg tttgctgctg tcgtacttca tttccaggcc tttcgatacc
    37021 tgtaaaacgc cattacttaa acttgcgccg tgttccatca aactgcgtaa ttgtttaccc
    37081 gtgagttcca tcgtcaccag ttcgttgggg aacgggaagg tactgatgac gccgcccatc
    37141 gtaatcgccc ctgcggggat ctcattgcga atgccgccag agttggttaa cgccaattgg
    37201 gtgtttttac ccgccgctac cagtaaagca tcagccgcca ggttcccgag ggaagccgat
    37261 tcaccatagg cacgttttaa ttcaaccggc gattgcgcga ccgtttgttg caccacttca
    37321 tcaagctttt tattccagcc gtcgatcacc tgttttgttt gcggatcggg cttccactcg
    37381 tcggcgtaaa tggttttaag ctcgaagttt ttcaccgtaa aatcatgcgg cttctctttg
    37441 tagtccagta ccagtttacc gacatcaatc ccaccgctgt cagtggagag gatgagcgta
    37501 ttgccgactt taatcggttc cggcgtaccc acatgtgcat gcccggtgat caaaatatcc
    37561 agccctttca cctgacttgc cgtctgaata tctttatcca gtgcgcggcg cacatctgtg
    37621 ccccccatac tggactggcg ggccggaaca ccttcgtgaa tcagcgcaac ggtcaaatca
    37681 accttgcctt tgagttcatc gatataacgt tgtagccatt taatttcatc acgcgcctca
    37741 atacccactc gcgttgccgc agataccgta tcattaaagg caaatacacc gtgcaaacca
    37801 atcacgccaa ttttcacgcc gtctttttca atgatggtat agggcttatc ccagaatgat
    37861 ttactgctgt tctgataaaa aacattaccc tgcacaatcg ggaattttgc ctgactcaac
    37921 tgtaataacg tattgtccca gccgtgatca aattcatgat tacctatagt gaccgcatcg
    37981 aacggcatgg tattcataat atcgataatc gccttgcctt tagtcaggct gctgatatac
    38041 ggcccggtaa aatagtcacc cgcatcaaaa aaccaggtcg ctttgttttt agctttttct
    38101 tgtttaacaa gcgtagtgat atttgcccag ccgccaatat ctcgtttacc gtcagcaatc
    38161 cacggcactt tataaggctc tacatgtgca tggaggtcgt tggtataaat gatggtgaca
    38221 tctttggcgc aagcccaaaa cggcagtgtt aatgcgatac ccgcagcaag cattttaatt
    38281 ttcataaaca atcccttcca gtgagataaa ggattgctac attacgttct gaaagaatta
    38341 tttatgtgag agcaatcaca tccacaaggg agcgttgccg gacaaaatca acgaccttgt
    38401 gaaatcgttg gtgatatatg tcgactctgt ttacgattaa tgcctgcaag tcgtttggtt
    38461 gccgtaattt agggcagcca acttcgacag attacagctg gccagactat cgactgggtt
    38521 atccggcact gcactgtcgg gcatgtggaa gttacccgcc gttgtttgac gaacagcaat
    38581 ttcgtgactg gttgtcagtt cacttatcta cttttgcaac tgagaaaggt catttctgcc
    38641 cggtatgtta tggcacaaag acgatttgtt atggccacaa tccacagggg tcgcaacgca
    38701 ttcaatgtcg taactgcaaa aaagtctgga cacctaaaca atatcagaaa gaaataacgc
    38761 ctcctgaaat aatcgaaacg gttgctcttc tggtgccatt tcagggagcc agcggcgggc
    38821 agaaactgta tgttttaatc agttttgatg ctcttcgcgg taatattctt catctttcta
    38881 ctaattacac gcagcatcag gctggagaaa gtctgcatta tcgatacaga ggaaatgcag
    38941 aaccagagtt acacgagagt aatattgtac aacgcgttga tatgcgcgaa gcacaatttc
    39001 tacgccgcag tcagtttgat gaaattcagt atggcagcgc agcgctcaaa cgcaatgcta
    39061 aaggtgttat tctgcgtccg gttatcacag cgcacgggca ttttagagta ctgaatattt
    39121 tattccctac agtaaaaaca catgtaattt cacacgagtg ttttttaaga ggtgcgatta
    39181 ttacggcctg ggcagaactg tttcgccaac agcaaggtga aatttggttt attgaagagg
    39241 aaatagctga ctataccgat aatacgccct ggcgttttca gggaaaaact tatcacggct
    39301 ggtggaaaaa tcagtggcaa ctctgggttc agggcaaaaa tcgtaaaatg gtatgtgcat
    39361 taacgggcgg aaataacagc aaagctgtaa tgctctcttt cgcaaccagc agacatttta
    39421 tcgactggct acataaacaa gcagtattta ctcacagcac cccgctttcc gcagggcgcg
    39481 ttacgcaaat actgctttct ctggctcagg attacaacaa ctgcgccaga cggttaatat
    39541 ccgactgaat cgccccggcg gtgacatcgc gccctgcacc tggcccgcgg atcaccagcg
    39601 ggttgtcgcg ataccagcgg ctttcgatgg caaagacgtt atcgcacggt agtagtgatg
    39661 ccagcggatg gtcttctcgc accgcttcca cgcctactcg cgctttgccg ttggcatcga
    39721 aacgcgccac gtagcgcaac accagcccca tttcacgggc cgcttccaac cgttgtacca
    39781 tctgctcatt aagttcatcg ccattttcaa agaaatggtc gatgcttcca ccttcgcaat
    39841 gggttggcac cagtgattca acacgcacct ggtccggttc aatgttgtaa cccgcttcac
    39901 gcgccagaat caccagcttg cgcatcacgt ctttgccgga aaggtcatca cgcggatcag
    39961 gctcggttaa gccctgctgc cacgcctgat ccaccagctc ggtaaacggc acgctaccgt
    40021 cgaattgcag gaacagccag gagagcgtgc cagagaagat cccactgatc gacaaaatgg
    40081 tatcgccgct gtcgatcaga tcgcgcacgg tatggttgat cggcaaaccc gcaccgacag
    40141 tggcattgta cagccagtga cgcccggttt tttcgaaggc gtcgtggatc tggcgatatt
    40201 tattgctgtc gctggctccc gccagtttgt tggcgctgat gacgtggaaa ccgtggctgg
    40261 caaaatcgag atactgatca gcaagctgct ggctggcggt aacgtccagc accactaaat
    40321 catcatacgg atgggcgcgc atccacagga acagcgactc ttcatcctgc tcgaccgctt
    40381 catcgttgaa gaaggctaac gcgcggctgg cgtccagccc gtcatagctc aacaggctgc
    40441 ggcggctgtc caccacgcct gccagcacaa attcaaagcc ggtacgcgcc gaaagcgtgc
    40501 tctgctcacg ggcgaacagt tccagccagc gggaaccgat attgcccttg ccgaacaata
    40561 ccaggccgat gcgtttttcc gcgcgaaaga cggactgatg cagaccctga atcaggcttt
    40621 cggtcggccc ggtgcgcagt actgccacca ggctgatgcc gtcatcggac tgccaggtaa
    40681 attcgaccgg ctggcctttc agttgctgcc agaagcggtg gcaatgcagc gggttacggg
    40741 ttacgcccgc cccaaccatc gccaccagcg ccagcccctg acgcaggcgc agttcgccag
    40801 gtaatcccgc ttcgtcgaga attttcagcg cactatcggc cacttccgag gtgtagcaaa
    40861 attgcagcaa ctggcgatcg ttatgtacgc caaccgccag tgggcgcacc tgagcacgtt
    40921 tcaggatttg gtcgatctct ttatgcgcca gtttgaaatc ctgactggca ggcacctgaa
    40981 actcaatcaa acagacatca tcgtggctgg tgacaatacg cgcgccagta ccggaagcca
    41041 gcacgcgttc aatgcgcgtg gaaccttgat ccggcgtgta gctacagcgc agttgcaggt
    41101 cgatttcact accggatact ggctgtaaag tacggacgtg aagaacgggg gccgccagac
    41161 gcgccagttc actggcttca tcaagacgca gcaacggcag caggcaggca tctttcactt
    41221 tacgcgggtc ggcgctatat accccggcga cgtcgctcca gatggttacg cgagaaacac
    41281 ccgccagcgc accgatttgt gtcgcggaat agtcggaacc gttacgcccc agcagcaccg
    41341 tttcaccggc gttgttacgg ctgataaacc cggtcaccac cagacgtttg cccggatgtt
    41401 gtaccagtag ctgttgcagc aacgggtaag aaagcccttc atcaacctgc ggctgcgcgg
    41461 cgcgttcagc gcgtaaaaac tcgcgggcat caagccaggc cgctggcagc ccttgttgat
    41521 taagtaccgc agacatcagg cgcgccgacc acacttcacc gtggcccacc acttccgcat
    41581 acaccgcatc gttaataccg ctgtcgagca gcgccgccag gcgttccaga tcgctgacaa
    41641 aagcgctaat gaggctatcg gcttcttcag cgggtagcag gccgctaatc agatcgcact
    41701 gataacgacg cagcgtttgt tgaacctgat gcgcagagag acgatcggtc tggcttagtt
    41761 tcaaccagtt aatcaactgg ttagtggtgc taccggcggc ggaaaccacc atcatatcgt
    41821 caggctgaga gtactccgcc ataatgcccg cgacacgcaa ataacacttc acatcagcca
    41881 gactactgcc accaaattta tgcagttgac gacctttcgc ccctgcctgc gcaatcacac
    41941 tcatttttac cccttgtttg cagcccggaa gccattttcc aggtcggcaa ttaaatcttc
    42001 gccatcttca ataccggtgg agatacgcag cagcgtctcg gagatcccgg cggcagcacg
    42061 cgcttctggt gccatgcctg catgtgtcat ggttgcggcg tgagagatta aactttccac
    42121 cccccctaat gattccgcca gcgtaaacaa cgacagccca cccaggaaac gacgcagcgt
    42181 ctgctcatcg ccatccagtt caaaactcaa cattgcgcca aagccttttt gctggcgcgc
    42241 ggcaatttca tgcccctgat tttccggcag cgacgggtga tacagttttt tcaccaacgg
    42301 ctgggtttgt agatatttca caatcgcctg cgcgttgcgc tgggccagct ccatacgcgg
    42361 caccagcgtt cgcaaaccac gtagcagcag atagctgtca aacgcgccgc ccgtcacgcc
    42421 aatattgttt gcccaccagg caagttcagt gacaacgtcc ggatctttag caatcaccac
    42481 gccggccacc acgtctgagt gaccgttcag atatttcgtg catgaatgca acaccagatc
    42541 ggcacctaat gccagcggat tttgtaatgc cgggcttaag aaggtgttat ccaccacgct
    42601 caccgccccg acttcccttg ccagatggca gattttcgca atatccacga cgcgtaacaa
    42661 tggattactt gggctttcta ccagtaccag tttgggtttt tctgccagcg ctgcccgtaa
    42721 tgcttgttca tcgccttgat caacaaacaa cacgcgatag caaccgcgtt tcgccaggct
    42781 gtcgaacagg cgatagctac ctccgtagca gtcgtgtggc gcaaccagca gatcgccagg
    42841 tttcaaaaag acggtagtga ccaggtgaat cgcggacatg ccggtattag taagtacggc
    42901 accggcaccg ccttccagtt ctgccagcgc acgctgaacc acatcgcgcg ttgggttgcc
    42961 acgacgcgag taatcatgcg cgcgcggttc attaaatccg gtaaagttat aggtgctgga
    43021 aagatggatg ggagggacaa cgcaaccata ctgttcgtcg tcatttaacc cgctacgcac
    43081 tgcgatggtg gcctgtttac gcgtcatgtg atgaagttcc ctgggcttgg tcggtgaaat
    43141 gtcaggcacc agagtaaaca ttgtgttaat ggacgtcaat acatctggac atctaaactt
    43201 ctttgcgtat agattgagca aatctcaaat agccgttaaa attatatgca ttatcacgcc
    43261 gacaggtgca ttacacgatg tcacggtaac gcctgtacgg taaactatgc gggtttacgg
    43321 tcagtaccca cattaactgt gtggtctagt ctcaatttat tgacgaagag gattaagtat
    43381 ctcatggctg aatggagcgg cgaatatatc agcccatacg ctgagcacgg caagaagagt
    43441 gaacaagtca aaaagattac ggtttccatt cctcttaagg tgttaaaaat cctcaccgat
    43501 gaacgcacgc gtcgtcaggt gaacaacctg cgtcacgcga ccaacagcga gctgctgtgc
    43561 gaagcgtttc tgcatgcctt taccgggcaa cctctgccgg atgatgccga cctgcgtaaa
    43621 gagcgcagcg acgaaatccc ggaagcggca aaagagatca tgcgtgagat ggggattaac
    43681 ccggagacgt gggaatacta aaacggaaaa gagcggcgcg gagttaacca gccgcttttt
    43741 tcatacatgg acgtttaact atgaaaatca ggctactgat ccccggcctg ctggtttctg
    43801 tgcctgcatt tgcctggcaa ccacaaaccg gcgacatcat ctttcagatc tctcgctcat
    43861 cgcaaagtaa agcgatccaa ctggcgaccc attccgatta cagccacacc ggtatgctgg
    43921 tgatacgcaa caaaaagccc tacgtttttg aagcggtcgg cccggtgaaa tacaccccgc
    43981 tcaagcagtg gatcgcccat ggtgaaaagg gtaagtacgt tgttcgccgc gttgaaggcg
    44041 gactgagtgt tgaacaacag caaaaactgg cgcaaacggc aaaacgttat ctcggcaaac
    44101 cgtatgattt cagcttctca tggagcgacg atcgccagta ctgttcggaa gtggtgtgga
    44161 aagtttacca gaatgcgctg gggatgcgcg taggtgaaca gcagaagttg aaagagttcg
    44221 atcttagtaa cccgctggtt cagacgaagc tcaaagaacg ctacggcaaa aatatcccgc
    44281 ttgaggaaac ggtggtctcg ccacaagccg ttttcgatgc gccacaactc accacagtcg
    44341 ccaaagaatg gccgctgttt tcgtggtaat ggatgatgaa aaaagtaatt ccccccgtag
    44401 cgtgtttgtt gctttgtagt tgcaccacct ttccgcaagc tgtcgctccg gtaaacggtg
    44461 atgcctccaa ttagttgaat taaggatata atactcgctt ttaaggttgt ttcatggtca
    44521 cagttaacct tcattgtccc cgttgccagt ccgttcaggt ttaccgtcac gggcagaacc
    44581 caaaaagaca tgatcgattc cgcggccgtg actgtcaccg ggtatttcag ctcagttact
    44641 gttacgagcc ccgtaaacca ggagttaaag accaaatcgc tgaaatggct ttcaacggtg
    44701 ctggggttcg ctatactgcc cgtacgctga aaatcggcat taatacagtc atccgaactt
    44761 taaaaaactc tcgccacgaa gaataacgtc atccccggtc gctcatgctg atgtggcact
    44821 catctgcgaa cttagtcagc aatggagctt tgtcggcagt aaagcgcgac agcactggct
    44881 ctggtacgtg tacaacacga aaactggtgg cgttctggcc tacacttttg gcccccggac
    44941 tgatgaaacc tgtcgtgaat tgctggcgct gcttaccctt ttaccatcgg catgttgacc
    45001 actgacgaat ggggtagtta cgctagagag ttaccaaagg agaagcatct gactggtaag
    45061 atttttactc agcacattga gcgtaacaat ctgaccctga gaacccgaat caaacgtctg
    45121 gcccgcagaa ccatctgttt ctcgcgttct gtagaacttc atgaaaaagt catcggtgct
    45181 tttatcgaaa atatatgttc tactaattgt agtcatcacc cttctgatga gctttccttg
    45241 gatgattacc agactgaata cacagccaaa gatttttacc tcattctgct cttttttctc
    45301 aaatgacata tattatattt tacatcatat tcataggcat atgacattcc cc
//
LOCUS       DADXDL010000028        45053 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.028, whole genome shotgun sequence.
ACCESSION   DADXDL010000028 DADXDL010000000
VERSION     DADXDL010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 45053)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 45053)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..45053
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.028"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..284)
                     /locus_tag="IRB70_001865"
     CDS             complement(<1..284)
                     /locus_tag="IRB70_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001604188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBC0631784.1"
                     /translation="MESANLDLEENKEIASKFERALGMGATLAELHGITPDTLEGVYA
                     YAYNFYEKGRLDEAELFFKFLCIYDFQNYNYLKGYAAVCQLKKDYQKAFD"
     gene            complement(586..879)
                     /locus_tag="IRB70_001866"
     CDS             complement(586..879)
                     /locus_tag="IRB70_001866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631785.1"
                     /translation="MKPTMLLMITVFLTFPAISQAESPFSSLQSAKEKTTVLQDLRKI
                     CTPQASLSDEAWEKLMLSDESNKQHIREAIVAMERNNQNNYWEALGKVECPDM"
     gene            1088..1906
                     /gene="nlpA"
                     /locus_tag="IRB70_001867"
     CDS             1088..1906
                     /gene="nlpA"
                     /locus_tag="IRB70_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpA"
                     /protein_id="HBC0631786.1"
                     /translation="MKLTTHHLRAGAALLLAGILLAGCDQSSSDAKHIKVGVINGAEQ
                     DVAEVAKKVAKEKYGLDVELVGFSGSLLPNDATNHGELDANVFQHRPFLEQDNQAHGY
                     KLVAVGNTFVFPMAGYSKKIKTVAQIKEGATVAIPNDPTNLGRALLLLQKEKLIILKE
                     GKGLLPTALDITDNPRHLQIMELEGAQLPRVLDDPKVDVAIISTTYIQQTGLSPVHDS
                     VFIEDKNSPYVNILVAREDNKNAENVKEFLQSYQSSEVAKAAETIFNGGAVPGW"
     gene            complement(1910..2833)
                     /locus_tag="IRB70_001868"
     CDS             complement(1910..2833)
                     /locus_tag="IRB70_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBC0631787.1"
                     /translation="MGSTRKGMLNVLIAAVLWGSSGVCAQYIMEQSQMSSQFLTMTRL
                     IFAGLILLTLSFVHGDKIFSIINNHKDAISLLIFSVVGALTVQLTFLLTIEKSNAATA
                     TVLQFLSPTIIVAWFSLVRKSRPGILVFCAILTSLVGTFLLVTHGNPTSLSISPAALF
                     WGIASAFAAAFYTTYPSTLIARYGTLPVVGWSMLIGGLILLPFYARQGTNFVVNGSLI
                     LAFFYLVVIGTSLTFSLYLKGAQLIGGPKASILSCAEPLSSALLSLLLLGITFTLPDW
                     LGTLLILSSVILISVDSRRRARKINRPARDE"
     gene            complement(2944..4128)
                     /locus_tag="IRB70_001869"
     CDS             complement(2944..4128)
                     /locus_tag="IRB70_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar efflux transporter"
                     /protein_id="HBC0631788.1"
                     /translation="MQKTATTPSKILDLTAAAFLLVAFLTGIAGALQTPTLSIFLADE
                     LKARPIMVGFFFTGSAIMGILVSQFLARHSDKQGDRKLLILLCCLFGVLACTLFAWNR
                     NYFILLSTGVLLSSFASTANPQMFALAREHADRTGRETVMFSTFLRAQISLAWVIGPP
                     LAYELAMGFSFKVMYLTAAIAFVVCGLIVWLFLPSIQRNIPVVTQPVEILPSIHRKRD
                     TRLLFVVCSMMWAANNLYMINMPLFIIDELHLTDKLAGEMIGIAAGLEIPMMLIAGYY
                     MKRIGKRLLMLIAIVSGMCFYASVLMATTPAIELELQILNAIFLGILCGIGMLYFQDL
                     MPEKIGSATTLYANTSRVGWIIAGSVDGIMVEIWSYHALFWLAIGMLGIAMICLLFIK
                     DI"
     gene            complement(4512..4658)
                     /locus_tag="IRB70_001870"
     CDS             complement(4512..4658)
                     /locus_tag="IRB70_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001280588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631789.1"
                     /translation="MDDERLKNPPVGSSVLERIRDIRASMRRVYLQVICPPADSQPTV
                     SPLR"
     gene            complement(4767..4861)
                     /locus_tag="IRB70_001871"
     tRNA            complement(4767..4861)
                     /locus_tag="IRB70_001871"
                     /product="tRNA-Sec"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(4825..4827),aa:Sec,seq:tca)
     gene            5154..6536
                     /locus_tag="IRB70_001872"
                     /pseudo
     CDS             5154..6536
                     /locus_tag="IRB70_001872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418114.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside-pentoside-hexuronide family
                     transporter"
     gene            6546..8864
                     /gene="yicI"
                     /locus_tag="IRB70_001873"
     CDS             6546..8864
                     /gene="yicI"
                     /locus_tag="IRB70_001873"
                     /EC_number="3.2.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-xylosidase"
                     /protein_id="HBC0631790.1"
                     /translation="MKISDGNWLIQPGLNLIHPLQVFEVEEQGNEMVVYAAPRDVRER
                     TWQLDTPLFTLRFFSPQEGIVGVRIEHFQGALNNGPHYPLNILQDVKVTIENTERYAE
                     FKSGNLSARVSKGEFWSLDFLRNGERITGSQVKNNGYVQDTNNQRNYMFERLDLGVGE
                     TVYGLGERFTALVRNGQTVETWNRDGGTSTEQAYKNIPFYMTNRGYGVLVNHPQCVSF
                     EVGSEKVSKVQFSVESEYLEYFVIDGPTPKAVLDSYTRFTGRPALPPAWSFGLWLTTS
                     FTTNYDEATVNSFIDGMAERNLPLHVFHFDCFWMKAFQWCDFEWDPLTFPDPEGMIRR
                     LKAKGLKICVWINPYIGQKSPVFKELQEKGYLLKRPDGSLWQWDKWQPGLAIYDFTNP
                     DACKWYADKLKGLVAMGVDCFKTDFGERIPTDVQWFDGSDPQKMHNHYAYIYNELVWN
                     VLKETVGEEEAVLFARSASVGAQKFPVHWGGDCYANYESMAESLRGGLSIGLSGFGFW
                     SHDIGGFENTAPAHVYKRWCAFGLLSSHSRLHGSKSYRVPWAYDDESCDVVRFFTQLK
                     CRMMPYLYREAARANARGTPMMRAMMMEFPDDPACDYLDRQYMLGDNVMVAPVFTEAG
                     DVQFYLPEGRWTHLWHNDELDGSRWHKQQHGFLSLPVYVRDNTLLALGNNEQRPDYAW
                     HEGTAFQLFNLQDGHEAICEVPAADGSVLFTLKAARTGNTITVNGAGVAKNWTLCLRN
                     VVKVNGLQGGSQAESELGLVVTPQGNALTITL"
     gene            9159..10712
                     /locus_tag="IRB70_001874"
     CDS             9159..10712
                     /locus_tag="IRB70_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBC0631791.1"
                     /translation="MQMITSRQNRLLRFLLPRREYTTIVTIAGYLNVSEKTIQRDLRL
                     LEQWLGQWRINVEKRAGAGVMLSAENIADLLHLDHLLGAECEEIDGVMNNARRVKIAS
                     QLLSETPNETSISKLSERYFISGASIVNDLRVIESWLAPLGLSLIRSPSGTHIEGSEG
                     QVRQAMALLINGIINHNEPQGVVYSRLDPGSYKALVHYFGEEEVLFVQSLLLDMENEL
                     SWSLGEPYYVNIFTHILIMMYRNTHGNALSREEDQTRQYDENIFNVASQMIHKIEQRI
                     AHTLPDDEVWFIYQYIISSGVAIDGQKDVSIISHMQASDEARLITWRLITVFSDIVDC
                     DFSEDSALYDGLLVHIKPLINRLNYRIHIRNPLLEDIKAELADVWRLTQYVVNQVFKT
                     WGENAVSEDEVGYLTVHFQAAMERQIARKRVLLVCSTGIGTSHLLKSRILRAFPEWTI
                     VDVISAANLSQVLPDNIELIISTINLPTVTMPVAYVTAFFNDADIKRVTEMVITEKLH
                     HATSRVVEI"
     gene            10739..11209
                     /locus_tag="IRB70_001875"
     CDS             10739..11209
                     /locus_tag="IRB70_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007370547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBC0631792.1"
                     /translation="MDITKILNTNRVILDMQATNKAEAIEELTNLLKKDGAIDCRETF
                     IKDVWQREAEGSTGFENHIAIPHGKSSAVINTTLAIGRTRQDIPWETLDGSSVRCIIL
                     FAVRLEDQNTTHIRLLSQVAGALADDDIIEQLLVETSPQKIIDLFSQYAQSDVC"
     gene            11227..11541
                     /locus_tag="IRB70_001876"
     CDS             11227..11541
                     /locus_tag="IRB70_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001028073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIB"
                     /protein_id="HBC0631793.1"
                     /translation="MNIVCVAACTAGIAHTYIAREKLIKGAKALGHTIKVETQGTIGT
                     ENELQAADISAADVVILAVDVKIKGEERFTNKRIVRVKTEIVIKSPVQFLEKVEKSLG
                     NK"
     gene            11566..12657
                     /locus_tag="IRB70_001877"
     CDS             11566..12657
                     /locus_tag="IRB70_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBC0631794.1"
                     /translation="MKENKIPVSQEIKKHLLTGISWMIPLIVAAGICIALGQVLGGTD
                     VGEKTGTIPWMLNQIGGWGMGLIVPLISAAIAYSIADRPGFAPGLIVGFLCGQIHTGF
                     IGGMLGGFLVGYTILLLKRYIRLPQSMQGLMPIMVLPVLSTIIGGLLMMTLIGKPIAW
                     LQEALIHLLESMQGGSRFLMGAILGAMATFDFGGPVNKTMSLFSDGLLVSGVYGPEAV
                     KFVGSIIPPFGITLSFLLTRHKYTRAEREALKAAFPMGICMITEGVIPIAARDLLRVV
                     GSCVVASAVAGGLIMVWGVESPVPHGGMFVVPLFTHPLLFCLALGIGTVICGVMLSLW
                     KKPVTERDEEFDELSDQKLKDEEITFTLE"
     gene            12669..13520
                     /locus_tag="IRB70_001878"
     CDS             12669..13520
                     /locus_tag="IRB70_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000457126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBC0631795.1"
                     /translation="MFADMKSMVMKAWHEHYALLAINCMNLESAHAAIRVAEKNRAPI
                     ILNLYQGHLAHFPAPVAAAVVKTLAESASVPVALALDHGKNPDCIRQAFRAGFSGLMI
                     DASAFPLEENVRQTRAVVELAASVQLCVEGELGHLADAPRYDQAANADLMTQPTDVEP
                     FIAQTGIDLLAVSVGTAHGMYAPGVVPAIDFQRLAEIFHCSSVPLALHGGSGTPFDQL
                     QLCTTLGVAKINVGAAIFERGKSALLHTLCHDISIELVDALKAMELAFEEAITPYLQA
                     SGSIGKA"
     gene            13601..14461
                     /locus_tag="IRB70_001879"
     CDS             13601..14461
                     /locus_tag="IRB70_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006687642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBC0631796.1"
                     /translation="MLVSMKELLQPTRQHGFAIGAFNVADNCFLRAVVDEAEATNTPA
                     IIAIHPSEHDFVGDAFFAHVREITQRSPVPFVLHLDHGASVEHVLRAIRCGFTSVMVD
                     GSLLPYEENVALTAEVVRLAHAVGVSVEGELGTIGQTGTSVEGGVSQVTYTDPAQAAD
                     FIARTGADTLAVAIGTAHGIYPKGMQPKLQMDILRDIAGRIDIPLVLHGGSANPDAEI
                     AESVTLGVGKINISSDMKYAYFQKVREILAKESWWDPNVIYPDAINAAREVIRHKMKL
                     FGSLGKASLY"
     gene            14509..15441
                     /locus_tag="IRB70_001880"
     CDS             14509..15441
                     /locus_tag="IRB70_001880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBC0631797.1"
                     /translation="MHYLGLDIGGTKIAAVVMDAHGWEIRRYRCPTQKSTYQQFVSCV
                     VALIEQIRRDVQRPMLTGIALPGSISPLTGLIKNANIQVINGHALQADLQQLLGQPVV
                     IANDGNCFALSEACDGAGQDYDVVFGITLGTGCGGGIAIKQRPFIGAWGNAAECGHIT
                     LPGYMEQEDGPSVSCYCGKHNCVESFVSGSGFSERYQQMTGNLLTPAAIVTLAQRGDA
                     CAMQQVARFRQQLARMLATIVNVVDPGVIVIGGGLSNVELLITDLNAEVAPLVFTDQF
                     TTPIVKAQHGDSSGMRGAAWLAMRNGEANETFTN"
     gene            15422..16102
                     /locus_tag="IRB70_001881"
     CDS             15422..16102
                     /locus_tag="IRB70_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lyxose/D-mannose family sugar isomerase"
                     /protein_id="HBC0631798.1"
                     /translation="MKRSQINYVIDKAHAIAQTFRVCLPEFAYFTVDDWLQLERDNWQ
                     EVVDLQLGWDITDFGRGDFNQTGLTLLTMRNGALGAAAYPKPYAEKMLQIQQDQQTPW
                     HFHTHKMEDILNRGGGDLCMQLAWANEANLCDDQRVITVSVDGQRRTMKPGETLVLKP
                     GQGICLPPRLYHRFWAEKAFVLGWEISMVNDDQHDNYFLEPGGRFPAIEEDEPVKWLL
                     CSEYGILR"
     gene            complement(16155..17855)
                     /locus_tag="IRB70_001882"
     CDS             complement(16155..17855)
                     /locus_tag="IRB70_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HBC0631799.1"
                     /translation="MKFIGKLLLYIFIALLVVIASLYFLLQTRWGAEHISAWVSENSD
                     YHLAFGAMDHRFSAPSHIVLENVTFGRDGQPATLVAKSVDIALSSRQLTEPRHVDTIL
                     LENGTLNLTDQTAPLPFKADRLQLRDMAFNSPNSEWKLSAQRVNGGVVPWSPEAGKVL
                     GTKAQIQFSAGSLSLNDVPATNVLIEGSIDNDRVTLTNLGADIARGTLTGNAQRNADG
                     SWQVENLRLADIRLQSEKSLTDFFAPLRSVPSLQIGRLEVIDARLQGPDWAVTDLDLS
                     LRNMTFSKDDWQTQEGKLSMNASEFIYGSLHLFDPIINAEFSPQGVALRQFTSRWEGG
                     MVRTSGNWLRDGKMLILDDAAIAGLEYTLPKNWQQLWMETTPGWLNNLQLKRFSASRN
                     LIIDIDPDFPWQLTALDGYGANLTLVTDHKWGVWSGSANLNAAAATFNRVDVRRPSLA
                     LTANSSTVNISELSAFTEKGILEATASVSQTPQRQTHISLNGRGVPVNILQQWGWPEL
                     PLTGDGNIQLTASGDIQANVPLKPTVSGQLHAVNAAKQQVTQTMNAGVVSSGEVTSTE
                     "
     gene            complement(17976..19367)
                     /gene="xanP"
                     /locus_tag="IRB70_001883"
     CDS             complement(17976..19367)
                     /gene="xanP"
                     /locus_tag="IRB70_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanP"
                     /protein_id="HBC0631800.1"
                     /translation="MSVSTLESENAQPVAQTQNSELIYRLEDRPPLPQTLFAACQHLL
                     AMFVAVITPALLICQALGLPAQDTQHIISMSLFASGVASIIQIKAWGPVGSGLLSIQG
                     TSFNFVAPLIMGGTALKTGGADVPTMMAALFGTLMLASCTEMVISRVLHLARRIITPL
                     VSGVVVMIIGLSLIQVGLTSIGGGYAAMSDNTFGAPKNLLLAGVVLALIILLNRQRNP
                     YLRVASLVIAMAAGYALAWFMGMLPESNEPMTQELIMVPTPLYYGLGIEWSLLLPLML
                     VFMITSLETIGDITATSDVSEQPVSGPLYMKRLKGGVLANGLNSFVSAVFNTFPNSCF
                     GQNNGVIQLTGVASRYVGFVVALMLIVLGLFPAVSGFVQHIPEPVLGGATLVMFGTIA
                     ASGVRIVSREPLNRRAILIIALSLAVGLGVSQQPLILQFAPEWLKNLLSSGIAAGGIT
                     AIVLNLIFPPEKQ"
     gene            19647..20852
                     /gene="gltS"
                     /locus_tag="IRB70_001884"
     CDS             19647..20852
                     /gene="gltS"
                     /locus_tag="IRB70_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312556.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/glutamate symporter"
                     /protein_id="HBC0631801.1"
                     /translation="MFHLDTLATLVAATLTLLLGRKLVHSVSFLKKYTIPEPVAGGLL
                     VALALLILKKSMGWEVNFDMSLRDPLMLAFFATIGLNANIASLRAGGRVVGIFLIVVV
                     GLLVMQNAIGIGMASLLGLDPLMGLLAGSITLSGGHGTGAAWSKLFIERYGFTNATEV
                     AMACATFGLVLGGLIGGPVARYLVKHSTTPNGIPDDQEVPTAFEKPDVGRMITSLVLI
                     ETIALIAICLTVGKIVAQLLAGTAFELPTFVCVLFVGVILSNGLSMMGFYRVFERAVS
                     VLGNVSLSLFLAMALMGLKLWELASLALPMLAILVVQTIFMALYAIFVTWRMMGKNYD
                     AAVLAAGHCGFGLGATPTAIANMQAITERFGPSHMAFLVVPMVGAFFIDIVNALVIKL
                     YLMLPIFAG"
     gene            complement(20886..22967)
                     /gene="recG"
                     /locus_tag="IRB70_001885"
     CDS             complement(20886..22967)
                     /gene="recG"
                     /locus_tag="IRB70_001885"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBC0631802.1"
                     /translation="MKGRLLDAVPLSSLTGVGAALSNKLAKINLHTVQDLLLHLPLRY
                     EDRTHLYPIGELLPGVYATVEGEVLNCNISFGGRRMMTCQISDGSGILTMRFFNFNAA
                     MKNSLATGRRVLAYGEAKRGKYGAEMIHPEYRVQGDLSTPELQETLTPVYPTTEGVKQ
                     ATLRKLTDQALDLLDTCAIEELLPPELSQGMMTLPEALRTLHRPPPTLQLSDLDTGQH
                     PAQRRLILEELLAHNLSMLALRAGAQRFHAQPLSANDALKNKLLAALPFKPTGAQARV
                     AAEIERDMALDVPMMRLVQGDVGSGKTLVAALAALRAIAHGKQVALMAPTELLAEQHA
                     NNFRNWFAPLGIEVGWLAGRQKGKARLAQQEAIASGQVQMIVGTHAIFQEQVQFNGLA
                     LVIIDEQHRFGVHQRLALWEKGQQQGFHPHQLIMTATPIPRTLAMTAYADLDTSVIDE
                     LPPGRTPVTTVAIPDTRRTDIIDRVRHACITEGRQAYWVCTLIEESELLEAQAAEATW
                     EELKLALPELNVGLVHGRMKPADKQAVMASFKQGELHLLVATTVIEVGVDVPNASLMI
                     IENPERLGLAQLHQLRGRVGRGAVASHCVLLYKTPLSKTAQIRLQVLRDSNDGFVIAQ
                     KDLEIRGPGELLGTRQTGNAEFKVADLLRDQAMIPEVQRLARHIHERYPQQAKALIER
                     WMPETERYSNA"
     gene            complement(22973..23662)
                     /gene="trmH"
                     /locus_tag="IRB70_001886"
     CDS             complement(22973..23662)
                     /gene="trmH"
                     /locus_tag="IRB70_001886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(18)-2'-O)-methyltransferase
                     TrmH"
                     /protein_id="HBC0631803.1"
                     /translation="MNPTRYARICEMLARRQPDLTVCMEQVHKPHNVSAIIRTADAVG
                     VHEVHAVWPGSRMRTMASAAAGSNSWVQVKTHRTIGDAVAHLKGQGMQILATHLSDNA
                     VDFREIDYTRPTCILMGQEKTGITQEALALADRDIIIPMIGMVQSLNVSVASALILYE
                     AQRQRQNAGMYLRENSMLPEAEQQRLLFEGGYPVLAKVAKRKGLPYPHVNQQGEIEAD
                     ADWWATMQAAG"
     gene            complement(23669..25777)
                     /gene="spoT"
                     /locus_tag="IRB70_001887"
     CDS             complement(23669..25777)
                     /gene="spoT"
                     /locus_tag="IRB70_001887"
                     /EC_number="3.1.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional GTP
                     diphosphokinase/guanosine-3',5'-bis pyrophosphate
                     3'-pyrophosphohydrolase"
                     /protein_id="HBC0631804.1"
                     /translation="MYLFESLNQLIQNYLPEDQIKRLRQAYLVARDAHEGQTRSSGEP
                     YITHPVAVACILAEMKLDYETLMAALLHDVIEDTPATYQDMEQLFGKSVAELVEGVSK
                     LDKLKFRDKKEAQAENFRKMIMAMVQDIRVILIKLADRTHNMRTLGSLRPDKRRRIAR
                     ETLEIYSPLAHRLGIHHIKTELEELGFEALYPNRYRVIKEVVKAARGNRKEMIQKILS
                     EIEGRLQEAGIPCRVSGREKHLYSIYCKMVLKEQRFHSIMDIYAFRVIVNDSDTCYRV
                     LGQMHSLYKPRPGRVKDYIAIPKANGYQSLHTSMIGPHGVPVEVQIRTEDMDQMAEMG
                     VAAHWAYKEHGETSTTAQIRAQRWMQSLLELQQSAGSSFEFIESVKSDLFPDEIYVFT
                     PEGRIVELPAGATPVDFAYAVHTDIGHACVGARVDRQPYPLSQPLTSGQTVEIITAPG
                     ARPNAAWLNFVVSSKARAKIRQLLKNLKRDDSVSLGRRLLNHALGGSRKLNEIPQENI
                     QRELDRMKLATLDDLLAEIGLGNAMSVVVAKNLQHGDASIPPATQSHGHLPIKGADGV
                     LITFAKCCRPIPGDPIIAHVSPGKGLVIHHESCRNIRGYQKEPEKFMAVEWDKETAQE
                     FITEIKVEMFNHQGALANLTAAINTTTSNIQSLNTEEKDGRVYSAFIRLTARDRVHLA
                     NIMRKIRVMPDVIKVTRNRN"
     gene            complement(25796..26071)
                     /gene="rpoZ"
                     /locus_tag="IRB70_001888"
     CDS             complement(25796..26071)
                     /gene="rpoZ"
                     /locus_tag="IRB70_001888"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013511051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBC0631805.1"
                     /translation="MARVTVQDAVEKIGNRFDLVLVAARRARQMQVGGKDPLVPEEND
                     KTTVIALREIEEGLINNQILDVRERQEQQEQEAAELQAVTAIAEGRR"
     gene            complement(26126..26749)
                     /gene="gmk"
                     /locus_tag="IRB70_001889"
     CDS             complement(26126..26749)
                     /gene="gmk"
                     /locus_tag="IRB70_001889"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000046969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBC0631806.1"
                     /translation="MAQGTLYIVSAPSGAGKSSLIQALLKTQPLYDTQVSVSHTTRQP
                     RPGEVHGEHYFFVNHDEFKEMISRDAFLEHAEVFGNYYGTSREAIEQVLATGVDVFLD
                     IDWQGAQQIRQKMPHARSIFILPPSKIELDRRLRGRGQDSEEVIAKRMAQAVAEMSHY
                     AEYDYLIVNDDFDTALTDLKTIIRAERLRMSRQKQRHDALISKLLAD"
     gene            27007..28689
                     /gene="ligB"
                     /locus_tag="IRB70_001890"
     CDS             27007..28689
                     /gene="ligB"
                     /locus_tag="IRB70_001890"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709426.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigB"
                     /protein_id="HBC0631807.1"
                     /translation="MKVWMAILISILCWQSSAWAVCPAWSPARAQEEISRLQQQIKQW
                     DDDYWKEGKSEVEDGVYDQLSARLTQWQRCFGNETRDAMMPPLNGAVMHPVAHTGVRK
                     MADKNALSLWMRERSDLWVQPKVDGVAVTLVYRDGKLNKAISRGNGLKGEDWTQKVRL
                     ISAVPQTVSGPLANSTLQGEIFLKRKEHIQQQMGGINARAKVAGLMMRQGNSDTLNSL
                     AVFVWAWPDGPHLMTDRLKDLATAGFTLTQTYTRAVKNADEVAHVRNEWWKAKLPFVT
                     DGVVVRAAKEPESRHWLPGQAEWLVAWKYQPVAQVAEVKAIQFAVGKSGKISVVASLA
                     PVMLDDKKVQRVNIGSVRRWQEWDIAPGDQILVSLAGQGIPRIDDVVWRGAERTKPTP
                     PENRFNSLTCYFASDVCQEQFISRLVWLGSKQVLGLDGIGEAGWRALHQTHRFEHIFS
                     WLLLTPEQLQNTPGIAKSKSAQLWHQFNLARQQPFTRWVMAMGIPLTRAALNASDERS
                     WSQLLLSTEQFWQQLPGTGSGRARQVIEWKENAQIKKLGSWLAAQQITGFEP"
     gene            complement(28686..29303)
                     /locus_tag="IRB70_001891"
     CDS             complement(28686..29303)
                     /locus_tag="IRB70_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimeric intracellular cation channel family
                     protein"
                     /protein_id="HBC0631808.1"
                     /translation="MLLHILYLVGITAEAMTGALAAGRRRMDTFGVIIIATATAIGGG
                     SVRDILLGHYPLGWVKHPEYVIIVATAAVLTTIVAPVMPYLRKVFLVLDALGLVVFSI
                     IGAQVALDMGHGPIIAVVAAVTTGVFGGVLRDMFCKRIPLVFQKELYAGVSFASAVLY
                     IALQHYVSNHDVVIISTLVFGFFARLLALRLKLGLPVFYYSHEGH"
     gene            complement(29594..30418)
                     /gene="dinD"
                     /locus_tag="IRB70_001892"
     CDS             complement(29594..30418)
                     /gene="dinD"
                     /locus_tag="IRB70_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312547.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein D"
                     /protein_id="HBC0631809.1"
                     /translation="MNEHHQPFEEIRHYGTEGQEFWSARELAPLLDYRDWRNFQKVLA
                     RATQACEASNQAASDHFVETTKMVVLGSGAQRELEDVHLSRYACYLVVQNGDPAKPVI
                     AVGQTYFAIQTRRQELADDEAFRQLREDEKRLFLRNELKEHNKQLVEAAQQAGVATAI
                     DFAIFQNHGYRGLYGGLDQKAIHQRKGLKKSQKILDHMGSTELAANLFRATQTEEKLK
                     RDGVNSKQQANTTHFDVGRKVRQTIQELGGTMPEELPTPQVSIKQLENSVKITEKK"
     gene            complement(30639..31502)
                     /locus_tag="IRB70_001893"
     CDS             complement(30639..31502)
                     /locus_tag="IRB70_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBC0631810.1"
                     /translation="MIRSMTAYARREIKGEWGSATWEMRSVNQRYLETYFRLPEQFRS
                     LEPVVRERIRSRLTRGKVECTLRYEPDVSAQGELILNEKLAKQLVTAANWVKMQSDEG
                     EINPVDILRWPGVMAAQEQDLDAIAAEILAALDGTLDDFIIARETEGQALKALIEQRL
                     EVVSAEVVKVRAHMPEILQWQRERLVAKLEDAQVQLENNRLEQELVLLAQRIDVAEEL
                     DRLEAHVKETYNILKKKEAVGRRLDFMMQEFNRESNTLASKSINAEVTNSAIELKVLI
                     EQMREQIQNIE"
     gene            31629..32345
                     /gene="rph"
                     /locus_tag="IRB70_001894"
     CDS             31629..32345
                     /gene="rph"
                     /locus_tag="IRB70_001894"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006803115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBC0631811.1"
                     /translation="MRPAGRSNNQVRPVTLTRNYTKHAEGSVLVEFGDTKVLCTASIE
                     EGVPRFLKGQGQGWITAEYGMLPRSTHTRNAREAAKGKQGGRTMEIQRLIARALRAAV
                     DLKALGEFTITLDCDVLQADGGTRTASITGACVALADALQKLVENGKLKTNPMKGMVA
                     AVSVGIVNGEAVCDLEYVEDSAAETDMNVVMTEDGRIIEVQGTAEGEPFTHEELLTLL
                     ALARGGIESIVATQKAALAN"
     gene            32411..33052
                     /gene="pyrE"
                     /locus_tag="IRB70_001895"
     CDS             32411..33052
                     /gene="pyrE"
                     /locus_tag="IRB70_001895"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBC0631812.1"
                     /translation="MKPYQRQFIEFALSKQVLKFGEFTLKSGRKSPYFFNAGLFNTGR
                     DLALLGRFYAEALVDSGIEFDLLFGPAYKGIPIATTTAVALAEHHDLDLPYCFNRKEA
                     KDHGEGGNLVGSALQGRVMLVDDVITAGTAIRESMEIIQANGATLAGVLISLDRQERG
                     RGEISAIQEVERDYNCKVISIITLKDLIAYLEEKPEMAEHLAAVKAYREEFGV"
     gene            33350..34309
                     /locus_tag="IRB70_001896"
     CDS             33350..34309
                     /locus_tag="IRB70_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-directed DNA polymerase"
                     /protein_id="HBC0631813.1"
                     /translation="MDATRITLLALDLFGSPGWSADKEIQRLYALSNHAGRHYRRIIL
                     SKRHGGQRLVLAPDYLLKTVQRNILKNVLSQFPLSPFATAYRPGCPIVSNAQPHCQQQ
                     QILKLDIENFFDSISWLQVWRVFRLAQLPRNVVTMLTWICCYNDALPQGAPTSPAISN
                     LVMRCFDERIGEWCQARGITYTRYCDDMTFSGHFNARQVKNKVCGLLAELGLSLNQRK
                     SCLIAACKRQQVTGIVVNHKPQLAREARRALRQEVHLCQKYGVISHLSHRGELDPSGD
                     LHAQATAYLYALQGRINWLLQINPEDEAFQQARESVKRMLVAG"
     gene            complement(34355..34951)
                     /gene="slmA"
                     /locus_tag="IRB70_001897"
     CDS             complement(34355..34951)
                     /gene="slmA"
                     /locus_tag="IRB70_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000818604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid occlusion factor SlmA"
                     /protein_id="HBC0631814.1"
                     /translation="MAEKQTAKRNRREEILQSLALMLESSDGSQRITTAKLAASVGVS
                     EAALYRHFPSKTRMFDSLIEFIEDSLITRINLILKDEKDTTARLRLIVLLLLGFGERN
                     PGLTRILTGHALMFEQDRLQGRINQLFERIEAQLRQVLREKRMREGEGYTTDETLLAS
                     QLLAFCEGMLSRFVRSEFKYRPTDDFDARWPLIAAQLQ"
     gene            complement(35058..35516)
                     /gene="dut"
                     /locus_tag="IRB70_001898"
     CDS             complement(35058..35516)
                     /gene="dut"
                     /locus_tag="IRB70_001898"
                     /EC_number="3.6.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000976070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBC0631815.1"
                     /translation="MMKKIDVKILDPRVGKEFPLPTYATSGSAGLDLRACLDDAVELA
                     PGDTTLVPTGLAIHIADPSLAAMMLPRSGLGHKHGIVLGNLVGLIDSDYQGQLMISVW
                     NRGQDSFTIQPGERIAQMIFVPVVQAEFNLVEDFDATDRGEGGFGHSGRQ"
     gene            complement(35494..36714)
                     /gene="coaBC"
                     /locus_tag="IRB70_001899"
     CDS             complement(35494..36714)
                     /gene="coaBC"
                     /locus_tag="IRB70_001899"
                     /EC_number="4.1.1.36"
                     /EC_number="6.3.2.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418096.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphopantothenoylcysteine
                     decarboxylase/phosphopantothenate--cysteine ligase CoaBC"
                     /protein_id="HBC0631816.1"
                     /translation="MSLAGKKIVLGVSGGIAAYKTPELVRRLRDRGADVRVAMTEAAK
                     AFITPLSLQAVSGYPVSDSLLDPAAEAAMGHIELGKWADLVILAPATADLIARVAAGM
                     ANDLVSTICLATPAPVAVLPAMNQQMYRAAATQHNLEVLASRGLLIWGPDSGSQACGD
                     IGPGRMLDPLTIVDMAVAHFSPVNDLKHLNIMITAGPTREPLDPVRYISNHSSGKMGF
                     AIAAAAARRGANVTLVSGPVSLPTPPFVNRVDVMTALEMEAAVNASVQQQNIFIGCAA
                     VADYRAATVAPEKIKKQATQGDELTIKMVKNPDIVAGVAALKDHRPYVVGFAAETNNV
                     EEYARQKRIRKNLDLICANDVSQPTQGFNSDNNALHLFWQDGDKVLPLERKELLGQLL
                     LDEIVTRYDEKNRR"
     gene            36886..37554
                     /gene="radC"
                     /locus_tag="IRB70_001900"
     CDS             36886..37554
                     /gene="radC"
                     /locus_tag="IRB70_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709417.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBC0631817.1"
                     /translation="MKNNAQLLMPREKMLKFGISALTDVELLALFLRTGTRGKDVLTL
                     AKEMLENFGSLYGLLTSEYEQFSGVHGIGVAKFAQLKGIAELARRYYNVRMREESPLL
                     SPEMTREFLQSQLTGEEREIFMVIFLDSQHRVITHSRLFSGTLNHVEVHPREIIREAI
                     KINASALILAHNHPSGCAEPSKADKLITERIIKSCQFMDLRVLDHIVIGRGEYVSFAE
                     RGWI"
     gene            37771..38007
                     /gene="rpmB"
                     /locus_tag="IRB70_001901"
     CDS             37771..38007
                     /gene="rpmB"
                     /locus_tag="IRB70_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008457442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBC0631818.1"
                     /translation="MSRVCQVTGKRPVTGNNRSHALNATKRRFLPNLHSHRFWVESEK
                     RFVTLRVSAKGMRVIDKKGIDTVLAELRARGEKY"
     gene            38028..38195
                     /gene="rpmG"
                     /locus_tag="IRB70_001902"
     CDS             38028..38195
                     /gene="rpmG"
                     /locus_tag="IRB70_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBC0631819.1"
                     /translation="MAKGIREKIKLVSSAGTGHFYTTTKNKRTKPEKLELKKFDPVVR
                     QHVIYKEAKIK"
     gene            38293..39102
                     /gene="mutM"
                     /locus_tag="IRB70_001903"
     CDS             38293..39102
                     /gene="mutM"
                     /locus_tag="IRB70_001903"
                     /EC_number="3.2.2.23"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-formamidopyrimidine
                     glycosylase/DNA-(apurinic or apyrimidinic site) lyase"
                     /protein_id="HBC0631820.1"
                     /translation="MPELPEVETSRRGIEPHLVGATILHAVVRNGRLRWPVSEEIYRL
                     SDQPVLSVQRRAKYLLLELPEGWIIIHLGMSGSLRILPEELPPEKHDHVDLVMSNGKV
                     LRYTDPRRFGAWLWTKELEGHNVLAHLGPEPLSDDFNGEYLHQKCAKKKTAIKPWLMD
                     NKLVVGVGNIYASESLFAAGIHPDRLASSLSLAECELLARVIKAVLLRSIEQGGTTLK
                     DFLQSDGKPGYFAQELQVYGRKGEPCRVCGTPIVATKHAQRATFYCRQCQK"
     gene            complement(39141..39620)
                     /gene="coaD"
                     /locus_tag="IRB70_001904"
     CDS             complement(39141..39620)
                     /gene="coaD"
                     /locus_tag="IRB70_001904"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBC0631821.1"
                     /translation="MQKRAIYPGTFDPITNGHIDIVTRATQMFDHVILAIAASPSKKP
                     MFTLEERVALAQQATAHLGNVEVVGFSDLMANFARNQHATVLIRGLRAVADFEYEMQL
                     AHMNRHLMPELESVFLMPSKEWSFISSSLVKEVARHQGDVTHFLPENVHQALMAKLA"
     gene            complement(39628..40905)
                     /gene="waaA"
                     /locus_tag="IRB70_001905"
     CDS             complement(39628..40905)
                     /gene="waaA"
                     /locus_tag="IRB70_001905"
                     /EC_number="2.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A) 3-deoxy-D-manno-octulosonic acid
                     transferase"
                     /protein_id="HBC0631822.1"
                     /translation="MLELLYTALLYLIQPLIWIRLWVRGRKAPAYRKRWGERYGFYRH
                     PLKPGGIMLHSVSVGETLAAIPLVRALRHRYPDLPITVTTMTPTGSERVQSAFGKDVQ
                     HVYLPYDLPDALNRFLNKVDPKLVLIMETELWPNLIAALHKRKIPLVIANARLSARSA
                     AGYAKLGKFVRRLLRRITLIAAQNEEDGARFVSLGAKNNQVTVTGSLKFDISVTPQLA
                     AKAVTLRRQWAPHRPVWIATSTHEGEESVVIAAHQALLQQFPNLLLILVPRHPERFPD
                     AINLVRQAGLSYITRSSGEVPSTSTQVVVGDTMGELMLLYGIADLAFVGGSLVERGGH
                     NPLEAAAHAIPVLMGPHTFNFKDICARLEQASGLITVTDATTLAKEVSSLLTDADYRS
                     FYGRHAVEVLYQNQGALQRLLQLLEPYLPPKTH"
     gene            41318..42376
                     /gene="rfaQ"
                     /locus_tag="IRB70_001906"
     CDS             41318..42376
                     /gene="rfaQ"
                     /locus_tag="IRB70_001906"
                     /EC_number="2.4.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptosyltransferase
                     RfaQ"
                     /protein_id="HBC0631823.1"
                     /translation="MDKPFRRILLIKMRFHGDMLLTTPVISSLKKNYPDAKIDVLLYQ
                     DTIPILSENPEINALYGIKNKKAKASEKIANFFHLIKILRANKYDLIVNLTDQWMVAI
                     LVRLLNARVKISQDYHHRQSAFWRNSFTHLVPLQGGNVVESNLSVLTPLGLESLVKQT
                     TMSYPPASWKRMRRELDHAGVGQNYVVIQPTARQIFKCWDNAKFSAVIDALHARGYEV
                     VLTSGPDKDDLACVNEIAQGCQTPPVTALAGKVTFPELGALIDHAQLFIGVDSAPAHI
                     AAAVNTPLISLFGATDHIFWRPWSNNMIQFWAGDYREMPTRDQRDRNEMYLSVIPAAD
                     VIAAVDKLLPSSTTGTSL"
     gene            42373..43497
                     /locus_tag="IRB70_001907"
     CDS             42373..43497
                     /locus_tag="IRB70_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBC0631824.1"
                     /translation="MIVAFCLYKYFPFGGLQRDFMRIAQTVAARGHHVRVYTQSWEGE
                     CPDVFELIKVPVKSHTNHGRNAEYFAWVQKHLREYPVDRVVGFNKMPGLDVYYAADVC
                     YAEKVAQEKGFFYRLTSRYRHYAAFERATFEQGKPTQLLMLTDKQIADFQKHYQTEAE
                     RFHILPPGIYPDRKYSQQPANSREIFRKKNGITEQQYLLLQVGSDFTRKGVDRSIEAL
                     ASLPDSLRHNTLLYVVGQDKPRKFEALAEKRGVRSNVHFFSGRNDVSELMAAADLLLH
                     PAYQEAAGIVLLEAITAGLPVLTTAVCGYAHYIVDANCGEAIAEPFRQETLNEILRKA
                     LTQSSLRQAWAENARHYADTQDLYSLPEKAADIITGGLDG"
     gene            43490..44287
                     /gene="rfaP"
                     /locus_tag="IRB70_001908"
     CDS             43490..44287
                     /gene="rfaP"
                     /locus_tag="IRB70_001908"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312532.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(I) kinase RfaP"
                     /protein_id="HBC0631825.1"
                     /translation="MVELKEPFATLWRGKDPFEEVKTLQGEVFRELETRRTLRFEMAG
                     KSYFLKWHRGTTLKEIIKNLLSLRMPVLGADREWNAIHRLRDVGVDTMYGVAFGEKGI
                     NPLTRTSFIITEDLTPTISLEDYCADWATNPPDVRVKRMLIKRVATMVRDMHAAGINH
                     RDCYICHFLLHLPFSGKEEELKISVIDLHRAQLRTRVPRRWRDKDLIGLYFSSMNIGL
                     TQRDIWRFMKVYFVAPLKDILKQEQGLLSQAEEKATKIRERTIRKSL"
     gene            44303..>45053
                     /locus_tag="IRB70_001909"
     CDS             44303..>45053
                     /locus_tag="IRB70_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide 1,3-galactosyltransferase"
                     /protein_id="HBC0631826.1"
                     /translation="MSAHYFNPQEMINKTIIFDERPAASVASSFHVAYGIDKNFLFGC
                     GVSITSVLLHNNDVSFVFHVFIDDIPEADIQRLAQLAKSYRTCIQIHLVNCERLKALP
                     TTKNWSIAMYFRFVIADYFIDQQDKILYLDADIACQGNLKPLITMDLANNVAAVVTER
                     DANWWSLRGQSLQCNELEKGYFNSGVLLINTLAWAQESVSAKAMSMLADKAIVSRLTY
                     MDQDILNLILLGKVKLIDAKYNTQFSLNYELK"
BASE COUNT        11034 a        10858 c        11815 g        11346 t
ORIGIN      
        1 atgtcgaatg ccttttgata atctttcttc aattgacaga cggcggcata tccttttaga
       61 tagttataat tttggaaatc ataaatacag agaaatttaa aaaagagttc agcttcgtca
      121 agtcttcctt tttcataaaa gttataagcg taagcataaa cgccttcaag ggtatccggg
      181 gttatgccat gcagctctgc aagcgttgct cccataccta atgcacgttc gaacttactg
      241 gcaatttctt tattttcttc taaatccaga tttgcgcttt ccatctctac tctctccttt
      301 cgaacattct ttgttcagac ttcaccattt tttagagggt ggtgatatca aaattcgctc
      361 atttttatgc ccatccgttg ggcttcgttt tctgcattaa aaacaagtat tgtttcaatg
      421 agataagatt ttctatgtga tgaaatgaaa ataatgtaga gggaaattta tccacaatcc
      481 tgatgaacgg gttcaatttt gattggaatt tgaaaaagca ggtgatttac tgatgtgcga
      541 gcttaagtca gcggctgctg gcctgagcgc ggaggtgtgc gaaattcaca tatccgggca
      601 ttccacctta cccagcgctt cccagtagtt attctgatta ttacgctcca tcgccacaat
      661 agcttcgcgg atatgttgtt tgttactctc atcagacaac attaattttt cccacgcttc
      721 gtctgataat gacgcctgtg gcgtgcaaat tttacgtaaa tcttgcaata ccgtggtttt
      781 ctcttttgcc gactgtagcg agctgaatgg cgactcggcc tgagaaatgg ctggaaaagt
      841 caggaatacg gtaatcatga gtagcatcgt tggcttcata gcggcaacct tctgcaaatg
      901 tgcatcgaat gaagcataag tgtagtttgc ttttaccgct ctcatcatgc tgtacgaaag
      961 gtgtttgcgt ggtcagtaag aagtgccagt tttttatacc tttttcttct attcgatagc
     1021 ttttcgtttt ttaaatcgta gtgttcttgc cattatagtc agttaatgat taaaaaaagg
     1081 ataaaaaatg aaactgacaa cacatcatct acgggcgggg gccgcattat tgctggcagg
     1141 aattctgctg gcaggttgcg accagagtag cagcgatgca aaacacatta aagttggcgt
     1201 tataaatggc gcagaacaag atgtcgcgga agtcgctaaa aaggtggcaa aagagaaata
     1261 tggcctcgat gttgaactgg taggatttag cggttcgttg ctaccgaacg atgcgacaaa
     1321 tcatggcgag cttgatgcga atgtcttcca gcatcggccc tttcttgaac aagataatca
     1381 ggcgcatggt tataaactgg tagcggtggg aaatacgttt gtcttcccta tggcgggtta
     1441 ttccaaaaaa atcaaaaccg tggcgcaaat aaaagaaggc gcgacagtgg cgatccccaa
     1501 cgacccgacc aaccttggtc gcgcgctttt actgttgcaa aaagagaagc taattattct
     1561 gaaagaggga aaagggttat tacctaccgc gctggatata accgataatc ctcgtcattt
     1621 gcagattatg gaactcgagg gggcgcagct cccgcgcgta ctggatgatc ccaaagttga
     1681 tgtggcgatt atcagcacca cttacattca gcagaccgga ctttctccgg tgcacgacag
     1741 cgtatttatt gaagataaaa attcgccgta tgtgaacatt ctggtagcac gggaagataa
     1801 taagaatgca gaaaacgtga aggaatttct gcaatcttat caatcatccg aagtcgctaa
     1861 agcggcagaa accatcttta acggtggcgc ggtgcctggc tggtaattct cactcatccc
     1921 gcgccggacg atttattttt ctggcgcggc gacgggaatc cactgaaatc aaaatcactg
     1981 atgacagaat cagcagcgtt cccagccagt ccggtaatgt gaatgtgatc cccagtaaca
     2041 gcaaagagag cagcgcgcta cttaatggtt ctgcacagct taaaatgctg gcttttggac
     2101 cgccaattaa ttgtgctcct ttcaggtaca gactaaatgt cagggacgta ccaatgacca
     2161 ccaaataaaa aaacgccaga atcaaactgc cattaaccac aaaatttgtc ccttgtctgg
     2221 cataaaatgg cagcaggatc agaccaccaa tgagcatact ccagccgacg accggtaacg
     2281 tgccatagcg ggcaatcagc gttgagggat aggtggtata gaatgccgca gcaaatgccg
     2341 aggcaattcc ccagaataac gcggcaggag agatcgataa tgacgtcgga ttaccgtgtg
     2401 tcaccaataa aaaagtcccg accagcgatg tcaaaatagc gcaaaaaacc agaatgcccg
     2461 ggcgggattt acgcaccagt gagaaccagg cgacgataat cgtcggtgag aggaattgca
     2521 gcaccgttgc cgtggctgcg ttcgattttt cgatggttag caaaaaagtg agctgtacgg
     2581 ttagcgcgcc aaccacggaa aaaatcagca gactaatggc atctttgtga ttgttaataa
     2641 tagaaaagat tttatcgcca tgaacaaatg acagcgtcag cagaatcaaa ccggcgaata
     2701 tcaaacgcgt catagtcaaa aactgcgacg acatctggct ttgctccatg atgtattgcg
     2761 cgcagacccc tgaacttccc cacaacacgg cggcaatcag aacgttcagc atcccctttc
     2821 tggtggaacc catttttccc tctgcatact gttttgtcgt ttatgtatgc aggcatgata
     2881 gcaaaaatgg cgaggatggc tctgtttgcg ccacgccgat ttttcttagc ccagactggt
     2941 gagctaaata tctttaataa acagcaggca aatcatcgca atacccaaca tccctatcgc
     3001 cagccagaac aacgcgtggt agctccagat ttcaaccata attccgtcaa cagagccggc
     3061 gataatccag ccgacgcgtg aggtatttgc atataacgtt gtcgcagagc ctattttttc
     3121 aggcatcaga tcctgaaaat aaagcatgcc gataccacag agaataccaa ggaaaatggc
     3181 atttagaatt tgcaattcca gctcaattgc cggagtcgtc gccatgagta cgctggcgta
     3241 aaaacacata ccactcacga tagcaatgag cattaatagt cgcttgccaa tacgtttcat
     3301 gtaatagcct gcgattaaca tcatcggaat ttccagaccg gcagcaatac caatcatttc
     3361 tccagccagt ttatcggtta gatgcagttc atcaataata aatagcggca tatttatcat
     3421 gtagagatta ttcgccgccc acatcattga acagaccaca aaaagtagcc gtgtatcccg
     3481 ctttctatgg atggagggta aaatttctac gggttgggta acgacaggaa tatttctttg
     3541 tattgatggc aaaaacaacc agactatcag cccgcaaaca acaaatgcga tggctgcggt
     3601 gagatacatc actttaaaac taaatcccat tgccagctca taagcgagcg gtggcccgat
     3661 aacccaggca agcgagatct gagcacgtaa aaatgtactg aacatgaccg tctcacggcc
     3721 tgttctgtcg gcgtgttcac gggcgagggc gaacatttgc gggtttgcag tggaagcaaa
     3781 actactcaga agtacgcccg tagagaggag aatgaagtag ttgcgattcc acgcaaaaag
     3841 agtgcaggcc aacactccaa ataagcaaca tagcaggatc agtaatttac ggtcgccttg
     3901 tttatcggag tgccttgcca gaaattgact gaccagaatt cccataatag cgctaccggt
     3961 gaagaaaaaa cctaccatta taggacgggc tttcagttca tctgcgagga atatacttag
     4021 ggtgggagtc tggagagcgc ccgcaatacc cgtcagaaag gcgacaagta aaaatgccgc
     4081 ggcagtgaga tcaagtattt ttgatggagt ggtagccgtt ttttgcattc ttctgaatca
     4141 ccgggcgaca aaatataact gagttacaaa taagtaccag tcgaatgagt attgtattaa
     4201 gattttttga gtatcgctga tacaaccaga aagcaatgct agcgcaatat tatagggcca
     4261 gcaattgaga ttattagcaa aagcatgtta agagttaatc accgaattta tatattaatt
     4321 atagtaagac aatgagctat ttttgatagt aaaaataaaa caaatttatt tgatatatta
     4381 aatgaacaaa ttaatcttga tggcagtctg attattggtg aagtttacag gtcagttttt
     4441 ttcgccagcg gttaaaggaa tagaatcgtc gtataaaaaa agggtgttct ggggcgtgta
     4501 aaacaacatc ttcaccttaa tggcgataca gttggctgag agtcagcagg ggggcaaatc
     4561 acctgcaaat aaacacggcg catgctggcg cgaatatcgc ggatgcgttc gaggacagaa
     4621 gaaccgacag gcggattctt cagtcgctca tcgtccatca caaaactttt gatcaggtat
     4681 tcctgaagcc gattgaatat tgagcagtag aaaatatctg gattgacagt attacaaggg
     4741 gttggagaac gtcagaagag gcaaattggc ggaagatcac aggagtcgaa cctgcccggg
     4801 accgctggcg gccccaactg gatttgaagt ccagccgcct caccggagac gacgatcttc
     4861 cgcgcctcga ttgctacatg gaggcggggc gcattatagc tacttccttg agtttctaca
     4921 tcccccagat cagttttttc cgcctaatac acgcagcgta ttatcacgaa agcattataa
     4981 ttcatataaa acccatattt tacaatgata tatgagcgta atttacgcta ccacgatcac
     5041 ataaaacaag aatcataaat taataaccag atatcggaat attcgctctc gcagggatgg
     5101 tttacaaaat gcgttatcgg tctcagcacc cctatagcat caaggaaaag cagatgaaga
     5161 gtgaagtgtt gtccgttaaa gagaaaattg gttatggcat gggagacgcc gccagccaca
     5221 ttattttcga taacgtaatg ttatatatga tgttctttta taccgatatt tttggcattc
     5281 ctgccggatt tgtcggaacc atgtttttgg tcgctcgtgc actggatgcg atttccgatc
     5341 cttgcatggg gttgttggcc gatcgaacgc gctctcgctg gggtaaattt cgtccgtggg
     5401 tactgtttgg cgcactgcca ttcgggatcg tctgtgtact ggcctatagc acgccagatc
     5461 tcagtatgaa cggcaaaatg atctatgcag caattactta caccctactt accttacttt
     5521 ataccatcgt caatatccct tactgcgcat tgggtggtgt aatcaccaat gacccgactc
     5581 agcgtatctc gctgcaatcc tagcgttttg tgctggcgac cgcgggaggc atgctctcta
     5641 ctgttctgat gatgccgctg gttaatttaa ttggtggtga taataaacca ctcggtttcc
     5701 agggcggtat cgcggtcctt tccgtggtgg cattcatgat gctggcattt tgtttcttca
     5761 ccactaaaga acgcgttgaa gcaccaccta caacgacgtc tatgagggaa gatttacgtg
     5821 atatctggca aaacgaccag tggcgtattg tcggtttact aaccattttc aatattctgg
     5881 cggtatgcgt acgcggcggg gcgatgatgt attacgtcac atggattttg ggtacgccgg
     5941 aagtgtttgt cgcttttctt accacttatt gcgtgggtaa cctgattggt tccgcactgg
     6001 cgaaaccgct gaccgactgg aaatgtaaag tcactatctt ctggtggacg aacgccctgc
     6061 tggcagtgat tagcctcgcg atgttctttg ttcctatgca ggccagcatc accatgtttg
     6121 tcttcatctt cgtgattggt gtgttgcatc aactggtgac acctatccag tgggtaatga
     6181 tgtccgatac cgtcgattac ggcgagtggt gcaatggtaa acgcctgacc gggatcagtt
     6241 ttgctggcac gctgtttgtg ctcaaactgg ggttggcctt cggcggcgct cttatcggct
     6301 ggatgctggc ttatggcgga tatgatgcgg cagaaaaagc gcagaacagc gccacgatta
     6361 gcatcattat tgcgctattc acgattgttc cggcgatctg ttacttgctg agcgcgatta
     6421 tcgctaaacg ctactactcg ctcacgacgc acaatctgaa aaccgttatg gaacagctgg
     6481 cccagggcaa acgccgttgc cagcaacaat tcacctctca agaagtgcag aactaaggaa
     6541 cggcaatgaa aattagcgac ggaaactggt tgattcaacc tggcctcaat ttgattcacc
     6601 cgcttcaggt gttcgaggtt gaagagcagg gtaatgaaat ggtggtctat gctgcccctc
     6661 gtgatgtgcg tgaacgtacc tggcagcttg atacgccttt atttacgctg cgctttttct
     6721 ccccacagga aggtattgtc ggtgtacgga ttgagcattt tcagggggcg ctgaataacg
     6781 gtcctcatta tccgctcaat attttgcagg acgtgaaggt cacaatcgaa aacacagaac
     6841 gttacgctga gtttaaaagt ggcaacttaa gcgcgcgtgt cagcaaaggt gagttctggt
     6901 cactggattt tctgcgcaac ggcgaacgta ttaccggtag tcaggtgaaa aataatggct
     6961 acgtgcagga cacgaataat caacgaaatt atatgtttga gcggctggat cttggcgttg
     7021 gcgaaacagt ttacggtctg ggagagcgct ttactgccct ggtgcgcaat ggccagacgg
     7081 tagagacctg gaaccgggac ggcggcacaa gtactgaaca ggcgtataaa aatattccgt
     7141 tctatatgac taaccgtggt tatggggtac tggtcaatca tcctcaatgc gtctcttttg
     7201 aagtgggatc ggagaaagtc tccaaagtgc agttcagcgt tgagagtgaa tatctcgaat
     7261 actttgttat cgacggcccg acgccgaaag cggtacttga tagttatacc cgttttactg
     7321 gtcgtccggc gctgccgccc gcgtggtcct tcggcctgtg gctaaccact tcatttacca
     7381 ccaactacga cgaagcgacg gtaaacagct ttatcgatgg tatggcggaa cgcaatctgc
     7441 cgctgcatgt tttccacttt gactgtttct ggatgaaagc cttccagtgg tgcgattttg
     7501 agtgggaccc gctgactttc ccggacccgg aagggatgat ccgccgcctg aaagcgaaag
     7561 ggctaaaaat ctgcgtctgg attaacccct atatcgggca aaaatcccct gtctttaaag
     7621 agttacaaga gaaaggttat ttactcaaac gcccggacgg ttcgctgtgg cagtgggata
     7681 aatggcagcc aggtctggcg atttatgact ttaccaatcc ggatgcctgc aaatggtacg
     7741 ccgacaaact gaaaggtctg gtcgcgatgg gcgttgattg ctttaagacc gactttggcg
     7801 aacgtattcc aaccgatgtt caatggtttg atggttccga tccgcagaaa atgcataacc
     7861 attatgcgta catctacaac gaactggtgt ggaacgtgct caaggaaacc gttggcgagg
     7921 aagaagccgt cttgtttgcc cgctcggcct ccgtcggtgc gcagaaattc ccggtacatt
     7981 ggggtggcga ctgttacgct aactacgaat caatggcgga aagcctgcgc ggtggtttgt
     8041 ctattggcct ttctggtttt ggcttctgga gccacgatat cggcggcttt gagaataccg
     8101 ctccggcgca cgtttacaaa cgctggtgcg cgtttggttt gctctccagc catagccgtt
     8161 tacacggcag caaatcttat cgtgtgccgt gggcctatga tgatgagtcc tgtgatgtgg
     8221 tgcgcttctt cacgcaactg aaatgccgca tgatgccgta tctgtatcgt gaagctgcac
     8281 gtgcaaacgc ccggggtacg ccgatgatgc gggccatgat gatggagttc ccggacgatc
     8341 cggcttgtga ttaccttgac cgtcaataca tgttaggcga taacgtgatg gttgctccgg
     8401 tgttcactga agcgggcgat gtgcagttct acttgccgga aggtcgctgg acacacctgt
     8461 ggcacaacga tgaactcgat ggtagtcgct ggcataaaca gcagcacggc ttcctgagtc
     8521 tacccgttta tgtgcgtgat aacaccctac tggcgctggg caacaacgag caacgtcccg
     8581 attacgcgtg gcacgaaggc acggcattcc agctctttaa tctgcaagac gggcatgaag
     8641 ccatctgtga agtgcccgct gccgatggtt ccgttctttt caccctgaaa gcggcgcgta
     8701 ctggcaacac aattactgtg aatggtgcgg gcgtggcgaa gaactggacg ctgtgcttgc
     8761 gcaatgttgt gaaagtaaat ggtctgcaag gcggttcgca ggctgaaagt gagctggggc
     8821 tggtggtgac gcctcaaggg aatgcgctga caattacgtt gtaatctatt gaagaatgcc
     8881 ggatacgaat ggttttgtgt cgtgtccggt aaataatctc acatctggta ataaatattt
     8941 cttccatcgt atttgcgagc atgatcacga ttattcatca cgaaaatgtg atctgtgctg
     9001 aaaaatatcc cttaaccgcc ttgctttgtt ttatcactgt ccgggttacg gacatatttt
     9061 agtattgttg tgaaattatt ctgctttata tttaccctca gagatggcaa ctgaagctct
     9121 tcctcatagg gcttcttaat ctgtgataag ggtaaaaaat gcaaatgatt acctcgcgac
     9181 aaaacagatt attacgattc cttttacctc gaagggaata tacgactatt gttacgattg
     9241 ccggctattt aaatgtttcg gaaaaaacca ttcaacgtga tttacgttta cttgagcaat
     9301 ggctggggca atggagaata aatgttgaga agcgtgctgg cgcgggtgtg atgttaagcg
     9361 cggagaatat tgctgatttg ctgcatcttg atcatttgct gggagcagaa tgtgaagaga
     9421 ttgatggtgt aatgaataat gccaggcgcg ttaaaatagc gtcgcagtta ttaagtgaaa
     9481 caccgaatga aacgtcgatc agtaaattgt cagaacgcta ctttatcagc ggagcctcta
     9541 ttgttaatga cctgagagtg attgagtcct ggcttgcgcc gttggggtta tcgttgatcc
     9601 gcagcccaag tggtacgcat attgagggaa gtgaagggca agtccgacag gcaatggcat
     9661 tactgattaa cggcattatt aaccataatg agccgcaagg tgtcgtgtat tcacgtctgg
     9721 atcccggaag ctataaagca ttagtccatt attttggaga ggaagaagtg ttatttgtcc
     9781 agtcattgtt actggatatg gaaaatgaat taagttggtc tttgggagaa ccttattacg
     9841 ttaacatttt tactcacatc cttattatga tgtatcgcaa cacgcacggg aatgcgttat
     9901 caagagaaga agatcaaacc aggcaatatg atgaaaatat ctttaatgtt gccagtcaga
     9961 tgattcataa gatagaacaa cgaattgcac atacattgcc cgatgatgaa gtctggttta
    10021 tttatcaata tatcatttca tcaggtgtgg cgattgatgg acaaaaagat gtgagcatta
    10081 tttcacatat gcaggccagc gatgaagcgc gtctgattac ctggcgttta attacggtat
    10141 tcagtgacat cgtggactgc gattttagtg aagacagcgc attatatgat ggcttattgg
    10201 tgcatattaa gccgctgatt aaccgtttaa attatcgcat tcatatccgt aatccattgc
    10261 tggaagatat taaagcagaa ttagcggacg tctggcggtt gacgcaatat gtggtgaatc
    10321 aggtatttaa aacctggggt gagaatgcag tgagcgagga tgaagtgggt tacctgaccg
    10381 ttcattttca ggctgcgatg gagcggcaaa ttgcccgtaa acgcgtatta ctggtctgtt
    10441 caaccggaat cggaacttcg catctactga aaagccgtat tctgcgagcg tttcctgaat
    10501 ggacgattgt tgatgttatt tcagcagcga atttatcaca ggttttgcct gacaatatcg
    10561 aactgattat ttcgaccatt aatttgccta cagtcactat gccggtcgct tatgttaccg
    10621 ctttttttaa tgatgccgat attaagcggg tcactgaaat ggtgattacg gaaaaattac
    10681 atcatgcgac gtctcgggtc gttgaaattt aatgtcagaa ttttatgagg tatgacgaat
    10741 ggacataaca aaaatcctga atacgaatcg cgttatttta gatatgcaag cgacgaataa
    10801 agcggaggcg attgaagaat taactaatct tctcaaaaaa gatggtgcga tcgattgtcg
    10861 ggaaaccttt attaaagatg tctggcagcg cgaagcggaa ggctcgactg gttttgaaaa
    10921 tcatattgcg atcccgcatg gtaaatcttc tgcggtaatt aatactacgc tggcaattgg
    10981 ccgtacccgc caggatattc cctgggaaac gctggatggc agtagcgtgc gctgtattat
    11041 tttatttgcg gtacgtcttg aagatcaaaa taccacccat atccgtttac tttcccaggt
    11101 cgcgggcgcg ctggcggatg atgacatcat agaacaattg ttagttgaga cgagtccgca
    11161 aaaaatcatt gatctcttta gtcagtatgc acaatccgat gtctgctaaa taacagggag
    11221 tatgtcatga atattgtctg tgttgccgcc tgtacggcgg gtattgctca tacctatatt
    11281 gctcgtgaaa agttaatcaa aggagcaaaa gctctgggcc ataccattaa agttgaaacc
    11341 cagggaacca ttggtacaga aaatgaatta caggcggcag atatctctgc tgctgacgtc
    11401 gtgattcttg ctgtagatgt gaaaataaaa ggagaagaac gcttcaccaa taaacgtatt
    11461 gtgcgagtaa agacagagat cgtcattaaa tcgcccgttc aatttcttga aaaggtcgaa
    11521 aaatcactgg gaaacaaatg atccttatac tggagggatc ttaatatgaa agaaaataaa
    11581 attccggttt cacaggaaat taaaaaacat ttattaaccg gcatctcgtg gatgataccc
    11641 cttattgtgg ccgccgggat atgtattgcg ttggggcaag ttcttggcgg tacagatgtt
    11701 ggtgaaaaaa caggaacaat cccgtggatg cttaatcaga ttggcggctg gggaatgggg
    11761 ctgattgtgc cgctgattag cgcggcaatt gcctattcta ttgctgatcg tcccggtttt
    11821 gccccgggcc tgattgtcgg ctttctctgt gggcaaatcc ataccggatt tattggcggt
    11881 atgttgggtg gtttcctggt gggctacacc attttgctac ttaaacgcta tatccgcctg
    11941 ccgcagtcga tgcaaggact catgccaatc atggtgttgc cggtattaag caccattatc
    12001 ggtgggctgt taatgatgac gctgattggt aaacccatcg cctggttaca agaagcactg
    12061 attcatttgc tcgagtcgat gcagggcgga tcgcgcttcc tgatgggggc catacttggc
    12121 gcgatggcaa ccttcgattt cggtggtccg gtcaacaaaa ccatgtcgct gttttccgat
    12181 ggcttgctgg tcagtggcgt ctacggacca gaagccgtga aatttgtcgg ctcaatcatc
    12241 cctccgtttg gcatcacact ttcgttctta ctgacacgcc ataaatacac ccgtgcggag
    12301 cgcgaggcgc tgaaagccgc gtttccgatg gggatctgca tgatcactga aggagtcatt
    12361 ccgatcgccg cgcgtgacct gctgcgagta gtgggatctt gtgtggtggc atcggcggtt
    12421 gcgggcggct taatcatggt gtggggcgtg gagagtccgg ttccgcatgg cggcatgttt
    12481 gttgtgcctc tgttcaccca tcctctgctg ttttgcctgg cgctgggtat aggcacggtg
    12541 atttgtggcg tgatgctttc actctggaag aaaccggtaa cggaacgcga cgaagagttt
    12601 gacgaactga gcgatcaaaa gctgaaagat gaagagatca ctttcaccct cgaataaccg
    12661 gaggccctat gtttgccgat atgaaaagta tggtgatgaa agcctggcat gaacattacg
    12721 ccttactggc gatcaactgt atgaatctgg aaagtgctca cgcagctatc cgcgtggcgg
    12781 agaagaatcg cgctccgatc attctcaatc tctatcaggg gcatctggcg cattttccag
    12841 cacccgtcgc ggcggcagtg gttaaaacgc tcgcggaatc tgcctcagta ccggtcgctc
    12901 tggcgcttga tcatggcaaa aatccggact gtattcgtca ggcgtttcgt gctggtttca
    12961 gcggattaat gattgatgct tctgcttttc ccctggagga aaacgtgcgc cagaccaggg
    13021 cggtggtgga actcgccgcc agcgtgcagc tctgcgtgga aggcgaactg ggccatctgg
    13081 cagatgcgcc gcgttacgac caggccgcca atgcagacct gatgacgcaa cccactgatg
    13141 tggaaccgtt tatcgcgcag acaggcattg atctactggc cgtctcggta ggcacggcgc
    13201 acggcatgta cgcgcctggt gttgtacctg ctattgattt tcagcgtctg gcggagattt
    13261 tccactgctc gagcgtgcct ctggcattac atggcggtag cggtacgccg ttcgatcagc
    13321 tccagctctg tacgacgctg ggggtagcaa aaatcaacgt gggggcggcc atttttgaac
    13381 gggggaaatc cgcgctcctg cataccctct gtcacgatat atccattgaa ctggtggacg
    13441 cgctgaaagc tatggaactg gccttcgaag aagcgattac accgtattta caggcgagcg
    13501 gctctatcgg caaagcctga ttcattttct gtcatggcct ttatgccagt gcaataacgc
    13561 accggcaggg cggactacac gctgaaactg gagatttaac atgttagttt cgatgaaaga
    13621 attactgcaa cctacccgcc agcacggctt tgccattggc gcatttaatg tggcggataa
    13681 ctgtttcctt cgcgcagtcg tggatgaagc agaagcgaca aatactccgg cgattattgc
    13741 catccatccc agcgaacatg attttgtggg cgatgccttt ttcgctcacg ttcgcgaaat
    13801 tacccagcgt agtccggtcc cgtttgtact gcacctcgat catggtgcct ctgtagagca
    13861 tgttttgcgt gcgattcgct gcggatttac ctcagtaatg gtcgacggtt cgctgctgcc
    13921 gtatgaagaa aacgtggcgc tgaccgcaga agtggttcgc ctcgctcacg cggttggagt
    13981 gtcggttgag ggtgaactgg gaaccatcgg acaaacagga acgtcggtag aaggtggtgt
    14041 ttcacaagtg acctacacag atccggcgca ggccgccgat tttattgctc gtacaggtgc
    14101 cgacactctg gctgtggcga ttggtacagc acatggcatc tatccaaaag ggatgcagcc
    14161 gaagctgcaa atggacattt tgcgcgacat tgccggacgt attgatattc cgctggtgct
    14221 acacggtggt tcggcaaacc cggacgcgga gattgctgaa tcagttacgc tcggcgtcgg
    14281 caaaatcaat atctccagcg atatgaaata cgcctatttc cagaaagtgc gtgaaattct
    14341 cgctaaagag agctggtggg acccgaacgt catctatccg gatgcgatta acgcggcgcg
    14401 ggaagtcatt cgccacaaaa tgaaactgtt cggttcgctc ggtaaagcat cactgtacta
    14461 agccagaagg gcggggtgac ccgcctttta cgcaacaagg aacgagatat gcactatctg
    14521 gggttggata ttggtgggac caaaatcgcc gccgtcgtca tggatgcgca tggctgggag
    14581 attcgccgtt accgctgccc gacgcaaaag tcgacatatc aacaatttgt ctcatgcgtt
    14641 gtggcgctta tcgagcagat taggcgggac gttcaacgac cgatgctgac agggatcgcc
    14701 ttacccggca gtatctcgcc actcactggc ctgattaaaa acgcgaatat tcaggtgatt
    14761 aacggtcatg cgttacaggc tgatttgcag caattgcttg ggcaaccggt ggtgatagcc
    14821 aatgatggta actgtttcgc gctatcagaa gcttgcgacg gtgccgggca agattatgac
    14881 gtggtatttg gtattacgct tggtacgggc tgcggcggtg gcattgccat caagcaacga
    14941 ccgtttatag gggcctgggg aaatgctgcc gaatgcggtc atatcacgtt gccaggctat
    15001 atggagcagg aagatggtcc atcagtcagt tgctattgcg gcaaacacaa ctgcgtggag
    15061 tcgtttgttt ccggcagcgg ttttagtgaa cgctatcaac agatgactgg taacttgctc
    15121 actcctgcgg cgattgtcac cctggcacaa cgtggtgatg cttgtgccat gcagcaggtg
    15181 gcacgttttc gccaacagct tgcccgcatg ctggcaacca tcgttaacgt tgttgaccct
    15241 ggcgtgattg tgatcggcgg cgggctttcg aatgtggaac tgcttatcac cgatctgaac
    15301 gcagaagtcg ctccactggt tttcaccgat caattcacca ctcccattgt aaaagcacag
    15361 cacggcgaca gtagcggaat gcgtggcgct gcctggcttg ctatgcgcaa cggagaagcc
    15421 aatgaaacgt tcacaaatta attatgttat tgataaagca catgccattg cgcagacctt
    15481 ccgcgtttgt ttgccagagt tcgcctattt tacggtggat gactggctgc agctggaacg
    15541 ggataactgg caagaagtgg tcgacttaca gctcggttgg gatatcaccg attttggtcg
    15601 tggtgatttc aaccaaacgg gactaacact gctaacgatg cgcaacggcg cgctgggggc
    15661 ggcggcatat ccaaaaccgt atgctgagaa aatgttgcag atccaacaag atcagcaaac
    15721 tccctggcat tttcacaccc acaaaatgga agatatcctc aatcggggcg gtggagactt
    15781 atgcatgcag ttggcctggg ccaacgaagc caatctctgt gatgatcaac gagtcattac
    15841 cgtgagtgtt gatggtcagc ggcgtaccat gaaacctggt gaaacgctgg tgctaaaacc
    15901 ggggcagggc atttgcctgc cgccgcgtct gtatcatcgc ttctgggcgg aaaaagcgtt
    15961 tgttctcggc tgggaaatct cgatggtaaa tgatgaccaa cacgataact attttcttga
    16021 gccgggagga cgttttccgg cgatagaaga agatgaaccg gtgaaatggt tattgtgcag
    16081 tgagtatgga attttgcgct aataacgggg aacgctagcg ctgatatccg ctagcgtcct
    16141 tatttttact gcacctactc cgtcgacgta acttcaccac tggaaactac gcccgcattc
    16201 atggtttgag tcacttgctg ctttgcggcg ttcacggcat gcaattgccc gctaaccgta
    16261 ggtttcagcg ggacattggc ctgaatatcg ccactggcag taagctgaat attgccgtcg
    16321 ccagtcaacg gtaattcagg ccatccccac tgttgcaaaa tattcaccgg cacaccgcgt
    16381 ccattcaggc tgatatgggt ctgacgttgt ggcgtttgtg aaacactggc ggtggcttcc
    16441 agaatgcctt tttcagtaaa tgcactcagt tcgctgatat tcaccgtgct gctgttggcg
    16501 gtcagcgcca gcgacggacg acggacatca acacgattaa acgttgcggc ggcggcattc
    16561 agattcgccg aaccactcca gacgccccat ttatgatcgg taaccagcgt caggttggca
    16621 ccgtaaccat cgagcgcggt gagctgccac gggaagtcag ggtcgatatc aatgatcaga
    16681 ttgcggctgg cgctaaatct cttcagttgc aggttgttta accaaccggg tgtcgtttcc
    16741 atccacaact gttgccagtt ttttggcaag gtatattcca gtccggcaat tgccgcatca
    16801 tcaaggatca acattttccc gtcacgcaac cagttccctg acgttctgac catgccccct
    16861 tcccagcggc tggtgaactg gcgcagtgct acgccctgcg gggaaaattc cgcgtttata
    16921 atcggatcaa ataaatgcag cgagccataa ataaactcgc tggcgttcat cgacagttta
    16981 ccttcctgtg tctgccagtc atctttactg aaggtcatgt tgcgcaagct gagatcgagg
    17041 tcggtcaccg cccagtccgg accttgcaaa cgagcgtcga tgacttccag gcgaccaatc
    17101 tgcaacgacg ggacagagcg taatggcgca aagaagtcgg ttagcgattt ttcgctttgt
    17161 agacggatat ccgccagccg cagattttcc acttgccagc tgccgtcggc gttacgctgc
    17221 gcgtttccgg ttaatgtccc gcgggcgatg tcggcaccca ggttagtcag cgtaacgcga
    17281 tcgttatcaa tactgccttc aatcagtaca ttggtggcag gaacatcatt gagcgaaagc
    17341 gatccggcac taaactgaat ctgcgccttc gtacccagca ctttaccggc ttctggtgac
    17401 cacggaacca cgccgccatt tacccgctgc gcgctcagtt tccattcgct attcgggcta
    17461 ttaaacgcca tatcacgcag ttgcagacga tcggctttga acggtagcgg cgcggtctgg
    17521 tcggtgagat tcagcgtccc gttttccagc aggatggtat cgacatggcg tggttcggtc
    17581 agttgccgac tgcttagcgc aatgtcgaca ctttttgcta ccagggtcgc gggctggcca
    17641 tcacggccaa acgtgacgtt ctccagcacg atatgagatg gcgcggaaaa acggtgatcc
    17701 atcgcaccga aggccagatg atagtcgcta ttctcggaaa cccatgcgct gatatgttct
    17761 gctccccagc gggtttgcag aagaaaatag aggctagcga tcaccactaa cagagcgatg
    17821 aaaatgtaga gaagcagctt cccaataaat ttcatggtct tccatcccgt gaaatgcaca
    17881 taagggagtt atgcacgatt tacgcgcaat cctcaaggcg ggaatggtga aagaggtgag
    17941 actgcggcgg taattatctt accgccgcca gtgaattact gtttttctgg tgggaaaatc
    18001 agattcagca cgatggcagt aataccgccc gcggcaatcc cggaggagag taggtttttc
    18061 agccattcag gggcaaactg caaaatcagc ggctgctgag acacgcccag accgaccgcc
    18121 agcgacagcg cgataatcag aatcgcccgg cggttcagcg gctcacgaga aacgatacgc
    18181 acaccggagg cggcgatggt gccaaacatt acaagcgttg cgccgcccag aaccggttct
    18241 ggaatgtgtt gtacaaaacc gctcactgcc gggaacagac ccagcacgat caacatcagc
    18301 gcgacgacaa aaccgacata gcggctggca acaccggtta actggatcac cccgttgttc
    18361 tgcccgaagc aggagttcgg gaaggtatta aataccgccg agacaaacga gttcaggccg
    18421 tttgccagta cgccgccttt caggcgtttc atgtacagcg gaccggacac tggctgttcg
    18481 gaaacgtcag aggtcgccgt gatatcgcca atggtttcca gcgaagtgat cataaagacc
    18541 agcatcagcg gcagcagcag actccattca atgccaagac cgtaatagag cggcgttggc
    18601 accataatca gttcttgtgt catcggttcg ttgctttctg gcaacatgcc cataaaccac
    18661 gccagcgcat atccggccgc catcgcaatc accagtgagg ccacgcgtaa gtaagggtta
    18721 cgttgacggt taagcaggat aattaaggct aagaccacgc ctgccagcag cagatttttc
    18781 ggtgcgccga aggtgttatc gctcatggct gcgtaaccgc cgccaatgga ggtcagccca
    18841 acctgaatta gcgacaggcc gataatcatc accacaacgc cagaaaccag cggcgtaata
    18901 atgcggcgcg ccagatgcag aacgcgggag atcaccatct cggtacaact tgccagcatc
    18961 aacgtgccga acaaagctgc catcatggta ggaacatcag caccaccggt cttcagcgct
    19021 gtgccgccca taatcagcgg agcaacaaag ttgaagctgg tgccctgaat agacaacaac
    19081 ccggagccaa ccggacccca ggccttaatt tgaataatcg atgccacacc ggaggcaaac
    19141 agcgacatac taataatgtg ttgcgtgtct tgtgccggta aacccagcgc ctggcagatt
    19201 aatagcgctg gcgtgatcac cgcaacgaac atcgccagca aatgctgaca ggcggcaaac
    19261 agggtttgag gaagcggcgg acgatcttca agacggtaaa tcagttcgct gttttgagtc
    19321 tgcgcaaccg gttgcgcatt ttctgactcg agggtggaaa cagacatcga aaacaatccc
    19381 gtggtagcaa agcgggcatt ttagctgacc gaaagagaaa agcaaacgtt tgccacatcc
    19441 tcatctaaat atttaaatga gataaatgta cttttttata taacttttag ttgttttctg
    19501 cttaaaatcc atgccatttt tctattttca gcgaagaatt cgaaccagga aagcatgact
    19561 cgatactcgt catatttcgc cttactgcaa atgcgcgatg aagtatgacg agtatgaaag
    19621 agtgatgcgg acacaaagga gtaactatgt ttcatctcga tactttagca acgcttgttg
    19681 ccgcaacgct gacgttgctg ctcgggcgca agttggtcca ttccgtctcc tttttgaaga
    19741 aatacaccat accggaacct gttgcgggtg gtttattagt ggcgctggcg ctgctgatac
    19801 tgaaaaaaag catgggctgg gaagtcaact ttgatatgtc cctgcgcgat ccgttgatgc
    19861 tggctttctt cgccaccatt ggcctgaacg ccaacattgc cagtttgcgt gccggtgggc
    19921 gtgtggttgg catcttcttg attgtggttg ttggcctgtt ggtgatgcaa aatgccattg
    19981 gcattggtat ggctagcctg ttagggcttg atccgctgat ggggctgttg gccggttcta
    20041 ttacgctttc cggcggtcac ggtacgggag ctgcatggag taaattgttc attgaacgtt
    20101 atggcttcac caatgcgaca gaagtggcga tggcctgtgc aacgttcggt ttggtgctgg
    20161 gcggcttgat tggcggtccg gtggcgcgct atctggtgaa acactccacc acaccgaacg
    20221 gtattccgga tgaccaggaa gttccgactg cgttcgaaaa gccggatgtg ggccgcatga
    20281 tcacctcgct ggtgctgatt gaaactatcg cgctgattgc tatctgcctg acggtgggga
    20341 aaattgttgc gcaacttttg gctggtactg cttttgaact accgaccttc gtctgtgtac
    20401 tatttgttgg cgtgattctg agcaacggtc tgtcaatgat gggcttttac cgcgtctttg
    20461 agcgagcggt atccgtgctg ggtaacgtaa gcctgtcgtt gttcctggcg atggcgctga
    20521 tggggctgaa actgtgggag ctggcttcgc tggcgctgcc gatgctggcg attctggtgg
    20581 tacagaccat cttcatggcg ttgtatgcca tcttcgttac ctggcgcatg atgggcaaaa
    20641 actacgatgc ggcagtgctg gctgcgggtc actgtggctt tggccttggc gcgacaccaa
    20701 cggcaatcgc taacatgcag gcgatcactg aacgctttgg cccgtcgcac atggcgttcc
    20761 tggtcgtgcc gatggtcggt gcgttcttta tcgatatcgt caatgcgctg gtgattaagc
    20821 tgtatttgat gttgccgatt tttgccggtt aaccgatgaa gcggcggtct tctcaccgcc
    20881 gccttttacg cattcgagta acgttccgtc tccggcatcc agcgttctat cagggctttt
    20941 gcctgttgtg ggtaacgttc gtgaatatgt cgcgccaggc gctgaacttc cgggatcatc
    21001 gcctgatcgc gcagtaaatc cgccacttta aattcagcat tacccgtctg acgcgtacct
    21061 aacaattcgc cagggccgcg aatctctaag tctttctgtg caatcacaaa accgtcgttg
    21121 ctgtcgcgca gcacttgcag ccgaatttgc gcggttttgg agagcggcgt tttgtagagc
    21181 agcacgcagt gagaagccac cgcaccacga cctacacgcc cgcgaagctg gtgtaactgc
    21241 gccagaccca gacgctcagg gttttcgata atcatcagac tggcgttagg cacatcaaca
    21301 ccgacttcaa taacggtagt ggcaaccagc aggtgtagtt caccttgttt aaacgacgcc
    21361 atcaccgcct gtttatcggc aggtttcatc cgcccgtgta ccaggccgac gttcagttcc
    21421 ggcaacgcca gtttcaactc ttcccaggtt gcttccgccg cctgcgcttc cagcaattcc
    21481 gactcttcaa tcaacgtaca aacccagtat gcctgacgac cttcagttat gcaggcgtgg
    21541 cgcacgcggt caataatgtc ggtacggcgg gtatcaggaa tagcgaccgt agtcactggc
    21601 gtgcggcctg gcggcagctc atctatcacc gaggtatcga gatcagcata cgcagtcatc
    21661 gccagcgtgc gggggatggg cgtggcggtc atgatcaact gatgcggatg gaagccctgc
    21721 tgctggcctt tctcccataa cgccagacgc tgatgcacgc caaaacgatg ctgttcgtcg
    21781 ataatcacca gcgccagacc gttaaactgc acctgttcct ggaagatggc gtgtgttccg
    21841 acaatcatct gcacctgacc gctggcgatg gcttcctgct gtgccagccg cgctttacct
    21901 ttctgcctac cggcgagcca gcccacttcg ataccgagcg gtgcaaacca gttacggaag
    21961 ttattggcgt gctgttcggc gagtaattcg gttggtgcca tcaatgccac ctgtttgccg
    22021 tgggcaatcg cacgcagcgc ggcgagggcg gcgaccagcg ttttaccgga acctacatcg
    22081 ccctgtacca ggcgcatcat cggcacatcc agcgccatat cgcgctcgat ctccgccgct
    22141 acgcgtgcct gtgcgcccgt tggcttgaac ggtaaggcgg cgaggagttt atttttcagc
    22201 gcgtcattgg cgctcagtgg ctgggcatga aaacgctgtg ctccggcacg taaggctaac
    22261 atgctgaggt tgtgcgccag cagttcttcc agaatcagac ggcgttgtgc cggatgctgg
    22321 ccggtgtcca gatcgctaag ctgtagcgtc ggcggcgggc ggtgcaaagt gcgcaacgct
    22381 tccggtagcg tcatcattcc ttgtgacagt tccggcggca ggagttcttc aatggcgcag
    22441 gtgtcgagca gatcaagcgc ctggtcggtt aatttacgca gcgtggcctg ctttacgcct
    22501 tcggttgttg gataaaccgg cgtaagcgtt tcctgcaact ctggcgtact gagatcgccc
    22561 tgcacgcggt attccgggtg gatcatctcc gcgccatatt taccgcgctt tgcttctcca
    22621 taggccagca cgcggcggcc cgtcgccagg ctatttttca ttgccgcgtt gaagttgaaa
    22681 aagcgcatgg tgagaatgcc ggaaccgtcg ctgatctggc aggtcatcat ccgccgaccg
    22741 ccgaaggaga tattgcagtt cagcacttcg ccttccaccg tggcataaac gcccggtagt
    22801 agttctccga tggggtagag atgggtgcga tcttcgtagc gcaggggaag gtgtaagagt
    22861 agatcctgca cggtatgcag gttgattttc gccagcttgt tactaagcgc tgcgccaacg
    22921 cccgttaggg aactgagcgg gacagcatct aacaggcgac ctttcatggc acttatcctg
    22981 cagcctgcat ggtagcccac cagtcggcat cagcttcaat ttcgccctgc tgattgacgt
    23041 gggggtaagg caggcctttg cgttttgcga ctttcgccag caccggatag ccgccttcaa
    23101 acaacaggcg ttgttgctct gcttccggca acatgctgtt ttcacgcagg tacatgcccg
    23161 cattttgccg ctggcgctgg gcttcgtaaa gaatgagggc tgaggcaacg gaaacattca
    23221 gcgattgcac catgccaatc atcggaatga tgatgtcccg atccgccagg gccaacgctt
    23281 cctgcgtgat gcctgttttc tcctgtccca tcaaaataca ggtcgggcga gtgtaatcaa
    23341 tttcgcggaa atcgacagcg ttatcagaaa gatgggttgc cagaatctgc atgccctggc
    23401 ctttcagatg agcgacggca tcgccaatgg tgcggtgcgt tttcacctgt acccagctgt
    23461 tactacccgc agctgccgaa gccatggtgc gcatccgact gccaggccag acagcatgaa
    23521 cttcatgtac accaacggca tctgcggtac gaataatcgc agaaacgtta tgaggtttgt
    23581 ggacctgctc catgcagacg gtcagatcag gctgccgcct ggcgagcatt tcgcagatac
    23641 gtgcataacg tgttgggttc ataaaacatt aatttcggtt tcgggtgact ttaatcacgt
    23701 ctggcatcac gcggattttg cgcatgatat tcgccagatg cacacggtca cgggcggtca
    23761 gacgaataaa ggcgctgtag acgcgaccat ctttctcttc cgtattcaaa ctttgaatat
    23821 tcgaggtggt ggtgttaatt gccgctgtca ggtttgccag cgcgccctga tgattgaaca
    23881 tctccacctt gatttcggtg atgaactcct gcgccgtctc tttatcccat tccacagcca
    23941 taaacttctc tggctctttc tggtagccac ggatgttacg gcaggattca tggtggatca
    24001 ccagaccttt accggggctg acgtgggcga taatcgggtc gccaggaata gggcggcagc
    24061 atttcgcaaa ggtgatcagc acgccatcgg cacctttaat gggcagatgt ccgtgacttt
    24121 gggttgccgg tggaatggag gcgtccccat gttgcagatt tttcgcgacc accacgctca
    24181 tagcgttacc aaggccgatt tcagccagca gatcgtcaag cgttgccagc ttcatgcggt
    24241 ccagctcgcg ctgaatattt tcctgcggga tttcattgag cttgcggctg ccacccaacg
    24301 catggttgag cagacgacgg cccagactaa cagaatcatc acgcttgagg tttttcagca
    24361 actgacgaat tttggcgcgc gctttcgagc tgacgacaaa gttcagccac gcggcattcg
    24421 ggcgagcgcc cggtgcggta atgatttcaa cggtttgacc gctggtcagc ggctgcgaca
    24481 gcgggtaagg ctgacggtcg acacgcgcgc ccacgcaggc atggccgata tcggtatgca
    24541 ccgcataagc gaagtcgacg ggcgttgcac cggcaggcag ctctacaatg cgcccttccg
    24601 gtgtgaaaac gtaaatctca tcggggaaga gatcggattt aacgctctcg ataaattcaa
    24661 acgaactacc ggcgctctgt tgcagctcca gcaggctttg catccagcgc tgggcgcgga
    24721 tttgtgcggt agtactggtt tcgccgtgct ctttataagc ccagtgcgcg gcaacaccca
    24781 tctctgccat ctgatccata tcttcggtac ggatctggac ctcaaccggc acgccgtgcg
    24841 ggccaatcat cgaggtgtgc aaagactgat agccgttcgc ttttggaatg gcgatgtaat
    24901 cttttacgcg acccggacgc ggcttgtaca ggctatgcat ttgcccgagc acgcgataac
    24961 aggtgtcgga atcattgacg atcacgcgga aggcgtagat gtccatgatt gagtgaaaac
    25021 gctgctcttt gagcaccatt ttgcagtaaa tcgaataaag atgcttctcg cgaccactga
    25081 cgcggcacgg tattcccgct tcctgcaaac gcccttcgat ttcagaaaga atcttctgga
    25141 tcatctcttt acggttgccg cgcgcggctt tcaccacttc tttgattacg cgataacggt
    25201 tgggatacag cgcctcaaaa cccagctctt cgagttcggt tttaatgtgg tggataccta
    25261 aacggtgtgc cagcgggctg taaatttcga gggtttcacg ggcgatgcgg cgacgtttgt
    25321 ccgggcgaag tgagcccagc gtgcgcatgt tgtgggtacg gtcggcaagt ttgatgagaa
    25381 tgacgcggat atcctgcacc atcgccataa tcatcttgcg aaagttttcg gcctgcgcct
    25441 ctttcttatc gcggaacttg agcttatcaa gtttcgacac cccctctacc agctcggcga
    25501 cgcttttacc aaaaagctgt tccatgtcct ggtaggtggc gggtgtatct tcaatcacat
    25561 catgcagcag cgccgccatc agcgtttcat agtcgagttt catctcggcc agaatgcagg
    25621 caaccgccac cgggtgcgtg atatagggtt caccgcttga acgtgtttgc ccctcgtgag
    25681 catcacgtgc aacgagatac gcctgccgca gacgcttgat ttggtcttcc ggcaggtagt
    25741 tttgaatcag ctgattcagg ctttcaaaca gatacaaggg cgacccgctt tgtgattaac
    25801 gacgaccttc agcaatagcg gtaacggctt gtaattcagc ggcttcctgc tcttgctgtt
    25861 cctggcgttc gcgaacgtcg aggatctggt tgttgatcag accttcttcg atttcgcgca
    25921 gcgcgattac agtggtttta tcgttttctt ccggtaccag cggatccttt ccgcctacct
    25981 gcatctgacg agcgcgacgc gcggcgacca gtaccaggtc aaaacggtta ccaattttct
    26041 ctacagcgtc ctgaacagtt acgcgtgcca tacttaaaaa gctccacagg tgaagaaatg
    26101 actgggcatg atactgaaat caggttcagt ctgccaacaa tttgctgatt aaagcgtcat
    26161 gacgctgctt ttggcggctc atgcgcagac gttcggcgcg aataatggtc ttcaaatcgg
    26221 tcaacgcggt atcgaagtca tcattcacaa tcaggtaatc atattcggcg taatggctca
    26281 tttctgcaac agcttgcgcc atacgctttg caatgacctc ttcgctgtcc tgaccgcgac
    26341 cgcgtagacg gcggtccagt tcaattttgg acggcggtaa aataaagata ctccgcgcgt
    26401 gcggcatctt ctggcgaatt tgctgcgcac cctgccagtc gatatcgaga aaaacatcga
    26461 caccggtcgc cagtacttgc tcaatggcct cacgcgaagt gccatagtaa ttaccaaaaa
    26521 cttctgcgtg ttcgaggaac gcatctctgc taatcatttc tttaaattca tcatgattaa
    26581 caaagaaata atgttcaccg tggacttcac caggacgcgg ttggcgtgtg gtgtgtgaaa
    26641 cagaaacctg ggtgtcatac aacggttggg tttttaataa agcctgaatc aggctggatt
    26701 tacccgcgcc actgggggca gaaacaatat aaagcgtgcc ttgagccatg agtatctttc
    26761 gtatgtgatt agcgaaataa agcctacata cgagcttatt atacacggcg cggccatgtg
    26821 acgtagccct tgctcacact ttttgcgcaa agttgttgcg ttttgcgtag ctgcttccgc
    26881 atttgcctgt gattcactgc aataaagacg attctcagga agcgtcctcg cagactccgt
    26941 ttttgccact cggctttgct ttcatcacgt tgtatatctg cctgactatc tacagcggag
    27001 gtgatgatga aagtatggat ggcgatatta ataagtatct tgtgctggca atcatcggcg
    27061 tgggcggtct gtccggcctg gtcgccagcc agagcacagg aagaaatttc ccgcctgcaa
    27121 cagcaaataa aacagtggga cgatgactac tggaaggaag ggaaaagtga ggtggaagac
    27181 ggtgtttacg atcagttaag cgcccgtctc acgcagtggc aacgctgttt tgggaacgag
    27241 actcgcgacg ctatgatgcc gcctttaaac ggtgcggtta tgcatccggt tgcccatacg
    27301 ggtgtacgca aaatggcgga taaaaacgca ttaagtctgt ggatgcgcga acgtagcgat
    27361 ctttgggttc agccaaaagt tgatggcgtt gcggtaaccc tggtttatcg ggacgggaaa
    27421 ctgaacaaag caatcagtcg cggtaatggc ctgaaaggcg aggactggac gcagaaagtt
    27481 cgcttaattt ccgctgtgcc gcaaaccgtt agcgggcctt tagccaacag cacgcttcag
    27541 ggggaaatat ttctcaagcg taaggagcat atccaacaac aaatgggggg aataaatgcc
    27601 cgcgcaaaag ttgctggcct gatgatgcgc caggggaata gcgatacgct aaactcactg
    27661 gctgtttttg tctgggcatg gccggatgga ccgcatttaa tgaccgatcg tttaaaggat
    27721 ctggctaccg caggttttac tttaacgcag acgtataccc gcgcggttaa aaatgctgat
    27781 gaggttgcgc acgtacgcaa tgagtggtgg aaagcaaaat tacccttcgt caccgatggc
    27841 gtggttgtgc gagcggcgaa agaacccgaa tcccgtcatt ggctaccggg ccaggcggag
    27901 tggctggtgg cctggaaata tcaacctgta gctcaggttg ccgaagtgaa ggcgattcag
    27961 tttgcggtgg gtaagagcgg taaaatatcg gtggttgcgt cactcgcacc tgtcatgctg
    28021 gatgataaaa aagtccagcg ggtgaatatt ggttccgtca ggcgctggca ggagtgggat
    28081 attgcgcctg gtgatcagat cctcgtcagc cttgccggtc agggtattcc tcgcattgat
    28141 gatgtggtct ggcgcggtgc agaacgtaca aaaccgacac caccagaaaa ccgctttaac
    28201 tcgttgacct gctactttgc ttctgatgtt tgtcaggaac agttcatttc acgcttagtc
    28261 tggctggggt caaaacaggt tctggggctt gatggcattg gtgaggccgg ctggcgcgcg
    28321 ctgcatcaga ctcatcgctt tgagcatatc ttttcctggc ttttattaac gccagagcaa
    28381 ttacagaaca cgccggggat cgcgaaaagt aaaagtgcgc agttatggca tcagtttaat
    28441 ctggctcgtc agcagccttt tactcgctgg gtgatggcaa tgggaatacc gctaacccgg
    28501 gcggcgctta atgccagtga tgaacggtcc tggtcgcaac ttttattgag cacagaacag
    28561 ttctggcagc agttgccggg gactggatcg gggcgcgcca gacaggttat tgaatggaag
    28621 gaaaatgcgc aaatcaagaa gctgggcagt tggctggctg cccagcagat cacaggtttt
    28681 gaaccttagt gaccttcgtg gctgtagtaa aagaccggta atcccagctt aagacgtagc
    28741 gccagtaagc gggcaaaaaa gccgaatacc agggtggaga taatcaccac atcatggtta
    28801 gaaacataat gttgcagcgc gatgtacagc acggcggagg caaatgagac accggcatac
    28861 aactctttct ggaataccag tgggatgcgt ttacagaaca tatcgcgcaa aacgccgcca
    28921 aatacgccgg tcgtcacagc tgcgacaacg gcaatgatcg ggccgtgtcc catatccagt
    28981 gcaacctgtg cgccaatgat agaaaagact accagtccga gcgcatcgag caccagaaac
    29041 actttgcgca ggtaaggcat tacaggagca acgatagtgg tgagtactgc ggcggtagcg
    29101 acaataatca catattccgg gtgtttgacc cagccgagcg gatagtggcc cagcagaata
    29161 tcgcgcactg accctccgcc aattgcggtg gcggtcgcaa taataattac gccaaatgta
    29221 tccatgcgcc gtcgtccggc cgccagcgcc cccgtcatgg cttcggcagt aatgccaacc
    29281 aaatacaaaa tgtgtaacag catggctctc tccctaaaaa tctgtctggc agggtagcga
    29341 tttgtgcgca ttgtcacgat tgagattttt taaggtgaga ggaaattgat aatttttagt
    29401 tatgtgaaat cgttgttttc tgtagcgtag atgcattctt ctgacttctt gtctgagaaa
    29461 atgcataaga aaaagtaggt taaaactgag gggtggaaaa gaaaggtgca atgttagcca
    29521 ttgtgttcac tgcacctgga ccttggctta cgcatcgggt gtctcaatca tcaaaaagag
    29581 tttttagttt ctgctatttt ttctctgtaa tttttacact gttttccaac tgcttgatgc
    29641 tgacctgcgg ggtcggcaac tcctcaggca tggttccgcc aagttcctga atggtttgcc
    29701 tcaccttgcg acccacgtca aagtgtgtgg tgttagcttg ctgttttgaa ttcacgccat
    29761 cccgcttgag tttttcttct gtttgggtag ctcgaaagag attagccgcc agttctgttg
    29821 aacccatatg atccaggatc ttctgactct ttttcagccc cttccgctga tggatggctt
    29881 tctgatctaa tccaccatac agtccccggt aaccatgatt ctgaaatatg gcgaaatcga
    29941 tagctgtcgc taccccagct tgctgcgctg cctcaactaa ttgtttgtta tgttctttca
    30001 actcatttct cagaaaaaga cgcttttcgt cttcacgaag ttgcctgaaa gcttcatcgt
    30061 cagccagctc ctgccgtcgg gtctggatag caaaataagt ttgccctact gcaataaccg
    30121 gtttcgcagg gtcgccgttt tgtactacca ggtaacaggc atagcgggag agatgaacat
    30181 cttcaagttc tcgttgagcc cctgaaccta atacaaccat tttggtggtt tcaacgaaat
    30241 ggtcagatgc agcttgattg ctggcttcgc acgcttgagt cgcgcgggcc agtacctttt
    30301 gaaaattgcg ccagtcccga taatccagta acggtgccaa ttctctcgct gaccaaaatt
    30361 cttgcccttc agtgccataa tgccgtatct cttcaaaagg ttgatgatgt tcgttcattg
    30421 cccactccat gtgatatcga ttgcaaagaa agtaaatctg taactgtgtt tatatacagt
    30481 tgtgagtatc tcacgttctc agtgtgctgg gcaaaaaaac atcgcaaaat ctggagcagg
    30541 cacgcaaaac agaattgaag ttgcggggaa gaaaaatgcc gctctgtttg agtgggcggc
    30601 atttgtgaag gctgaaaagt aagaattggc gttacgagtt attcaatgtt ctgaatctgc
    30661 tcgcgcatct gctcaatcaa cactttcagc tcaatcgcgg agtttgtcac ttcggcattg
    30721 atagacttcg aagcaagagt gttcgactcg cggttgaact cctgcatcat aaagtccaga
    30781 cgacggccaa ccgcttcttt tttcttcaga atgttgtagg tctctttgac atgcgcttcg
    30841 aggcggtcaa gttcttcggc aacgtcaatt cgttgtgcca gcagaaccaa ctcctgctcc
    30901 agacggttgt tttccagttg cacctgagca tcttccagct tcgcgaccag acgctcacgc
    30961 tgccattgca ggatttccgg catatgggcg cggactttga ccacttcggc gctgacgact
    31021 tccagacgct gctcgatcaa tgctttcagc gcctgacctt cggtttcacg tgcgatgata
    31081 aagtcgtcca gcgtaccatc caacgccgcg agaatttcag cggcaatcgc gtcgagatcc
    31141 tgctcctggg ctgccatcac gcccggccag cgtagaatat caaccgggtt gatttctcct
    31201 tcgtcgctct gcatttttac ccagttcgcg gcagttacca gctgtttagc cagtttttcg
    31261 ttgaggatca gctcaccttg cgcgctaaca tctggctcat agcgcagggt acattccact
    31321 ttaccgcgcg tcaggcgaga acgaatacgc tcacgaacga caggttcaag gctacggaac
    31381 tgctccggca gacgaaagta agtttccaga taacgctggt ttaccgagcg catttcccag
    31441 gttgcgctcc cccattcacc cttgatttca cgccgggcgt aggcggtcat actgcggatc
    31501 atagacgttc ctgtttataa aaggagaggt ggaaggatta tagccatcga tgccttgtca
    31561 ggataggaat aaccgccgga agtccgtata atgcgcagcc acatttgttt caagccggag
    31621 atttcaatat gcgtccagca ggccgtagca ataatcaggt gcgtcccgtt accctgactc
    31681 gtaactatac aaaacatgca gaaggctcgg tgctggtcga atttggcgat accaaagtat
    31741 tgtgtaccgc ctctattgaa gaaggcgtgc cgcgcttcct gaaaggtcag ggccagggct
    31801 ggatcaccgc agagtacggc atgctgccac gttctaccca cacccgtaac gcgcgtgaag
    31861 cggcgaaagg taagcagggt ggacgcacca tggaaatcca gcgtctgatc gcccgtgctc
    31921 ttcgtgcggc agtagatttg aaagcgctgg gtgagttcac cattacgctg gactgcgacg
    31981 tgcttcaggc tgatggtggc acgcgtaccg cgtcgattac gggtgcctgc gtggcgctgg
    32041 cagatgcgct acagaagctg gtggaaaacg gcaagctgaa aaccaacccg atgaaaggga
    32101 tggtagccgc agtttctgtc ggcattgtca acggcgaagc ggtttgcgat ctggaatacg
    32161 ttgaagactc agccgcagag accgacatga acgtagtgat gaccgaagac gggcgcatca
    32221 ttgaagtgca ggggacggca gaaggcgaac cgttcaccca cgaagaatta ctcaccttgt
    32281 tggcgctggc ccgaggggga atcgaatcca ttgtagcgac gcagaaggcg gcgctggcaa
    32341 actgattttt aaggcgactg atgagtcgcc ttttttttgt ctgtagaaaa gtaagatgag
    32401 gagcgaaggc atgaaaccat atcagcgcca gtttattgaa tttgcgctta gcaagcaggt
    32461 gttaaagttt ggcgagttta cgttgaagtc cgggcgcaaa agcccctatt tcttcaacgc
    32521 cgggctgttt aataccgggc gcgatctggc actgttaggc cgtttttacg ctgaagcatt
    32581 ggtggattcc ggcattgagt tcgatctgct gtttggccct gcttacaaag ggatcccgat
    32641 tgccaccaca actgccgtgg cgctggcgga gcatcatgac ctggacctgc cgtactgctt
    32701 taaccgcaaa gaagcaaaag accatggtga aggtggcaat ctggtcggta gcgcgttaca
    32761 aggacgcgta atgctggtgg atgatgtgat caccgccgga acggcgatcc gcgagtcgat
    32821 ggaaattatt caggccaatg gcgcgacgct tgctggcgta ttgatttcgc tcgatcgtca
    32881 ggaacggggg cgcggcgaga tttcggcaat tcaggaagtt gagcgtgatt acaactgcaa
    32941 agtgatctct atcatcaccc tgaaagacct gattgcttac ctggaagaga agccggaaat
    33001 ggcggaacat ctggcggcgg ttaaggccta tcgcgaagag tttggcgttt aaaaatatgc
    33061 gctgtgcagg gtttttgctg tgcacagcgt gatgcgcttt aagatatcgt gttaatctgc
    33121 tttcgccagc agtggcaata gcgtttccgg ccttttgtgc cgggagggtc ggcgagtcgc
    33181 tgacttaacg ccagtagtat gtccatatac ccaaagtcgc ttcattgtac ctgagtacgc
    33241 ttcgcgtacg tcgcgctgac gcgctcagta cagttacgcg ccttcgggat ggtttaatgg
    33301 tattgccgct gttggcgcct cttttggccg ccgtgatgtg gagagtggaa tggatgctac
    33361 ccggataacc cttctggcgc tcgatttgtt cggctcgccg ggctggagcg ccgataaaga
    33421 aatacagcgg ttgtatgcgc tcagtaatca tgccggacgc cattaccgac gcattattct
    33481 ttctaaacgc cacggtggtc agcggctggt gttagcccct gattacttgc tcaaaaccgt
    33541 acagcgcaac attcttaaga acgtcctttc acaatttccg ctttcccctt ttgctacagc
    33601 ctaccgacca ggttgcccaa tcgtcagcaa cgcgcagcca cactgccaac agcagcagat
    33661 cctgaaactc gatatcgaaa actttttcga tagcattagc tggttacagg tctggcgtgt
    33721 gtttcgcctg gcccagttgc cacgtaatgt ggtaaccatg ctgacctgga tttgttgtta
    33781 taacgacgcg ttaccgcagg gggcaccaac ttcgccagcc atttccaatc ttgtgatgcg
    33841 ctgttttgat gaacgcatag gggaatggtg tcaggctcgg ggaattacct acacccgcta
    33901 ctgcgatgac atgacctttt caggtcactt caatgcccgc caggttaaaa ataaagtgtg
    33961 cggattgtta gcggagctgg gcctgagcct caatcaacgc aaaagctgcc tgatagctgc
    34021 ctgtaagcgc cagcaggtaa ccgggattgt tgttaatcac aaaccacagc ttgcccgcga
    34081 agcgcgccgg gcactgcgtc aggaagtaca cttgtgccaa aaatatggcg ttatttcgca
    34141 tcttagtcat cgtggtgaac ttgatccttc tggcgatctc cacgcacagg caacggcgta
    34201 tctttatgct ttgcagggaa gaataaactg gttattgcaa atcaaccctg aggatgaggc
    34261 ctttcaacag gcgagagaga gtgttaagcg aatgctggtt gcagggtaag aaaagcgtca
    34321 ggcagacgtt tctgcctgac cgtttagggg agaattactg caactgcgcg gcaattagcg
    34381 gccagcgggc gtcaaaatca tccgtcgggc ggtatttaaa ttcgctgcgg acaaagcgtg
    34441 acagcatacc ttcacaaaat gccagcaact ggcttgccag cagcgtttca tcggtggtgt
    34501 aaccttcacc ctcacgcatt ctcttttcac gcaatacctg acgcaactgc gcctcaatac
    34561 gctcgaacag ctggttgatg cgcccttgca ggcgatcctg ttcaaacatt agcgcatgac
    34621 cagtgaggat gcgggtcagg ccaggattac gctcaccaaa accgagaagc agcaacacaa
    34681 tcagacgcag gcgcgctgtg gtgtccttct catctttcag aatcagattg atgcgagtaa
    34741 tcaggctatc ttcgataaac tcaatcaggc tatcgaacat gcgggtctta ctggggaagt
    34801 ggcgatacag tgccgcttcg gaaacgccga cagaggcggc cagttttgcc gtcgtgatac
    34861 gttggcttcc atcgctggat tccagcatca gcgccagaga ctgaagtatt tcctcgcgac
    34921 ggttcctttt cgcagtttgt ttttctgcca tgttacaaaa tacccctgaa aataagcact
    34981 tgccaggcgg cacccacgct atgaccgcaa acgaaatgtt tgcggctatg ttatgacgtt
    35041 attcggatgc gtatgtgtta ctgacgacca gagtgaccaa agccgccttc accgcggtcg
    35101 gtggcgtcga aatcttccac cagattaaat tcagcctgta ctaccggaac aaaaatcatc
    35161 tgggcgatgc gttcgcctgg ttgaatggtg aagctgtcct gaccacggtt ccacacggaa
    35221 atcatcaact ggccctgata gtcagaatcg atcaatccta ccaggttacc aagcacgata
    35281 ccgtgcttat gtcccaatcc ggagcgcggc agcatcattg ccgccagtga aggatcggca
    35341 atatgaatcg ccagcccggt cggaaccagc gtagtgtcac ccggagccag ttctacggcg
    35401 tcgtcgagac aggcacgcag gtcaagtccg gcagagccag aggtggcata agtcgggagc
    35461 ggaaattcct tcccaacgcg cgggtccaga atcttaacgt cgattttttt catcataacg
    35521 ggtcacgatc tcgtcgagta ataattggcc aaggagctct ttgcgctcaa gcggtaagac
    35581 tttatctccg tcctgccaga aaaggtgtaa tgcgttgttg tcgctgttaa atccttgagt
    35641 tggctgggaa acatcgttcg cgcagatcag atcaaggttt ttacggatac gtttttgccg
    35701 agcgtattct tccacattat ttgtttcggc ggcaaatcca acgacgtagg gtcgatggtc
    35761 ttttagtgcg gcaacgcctg cgacgatatc ggggttttta accattttta ttgttaattc
    35821 atcaccctgc gtggcctgct ttttgatttt ctctggggcc acggtagctg cgcgataatc
    35881 cgccacggcg gcgcaaccga taaaaatatt ttgctgctgt acagatgcat tcacggcggc
    35941 ttccatttcc agcgcggtca tcacatcaac acggttaaca aacggtggcg tcggtagtga
    36001 aaccggacct gataccagcg tgacgttcgc gccacgacgg gctgcggcgg cggcgatagc
    36061 aaaacccatc ttgccggagc tgtgattaga gatataacgc acgggatcga gcggttcacg
    36121 cgtcggaccg gcggtaatca taatgttcag atgtttcagg tcgttgacgg gcgaaaaatg
    36181 cgccaccgcc atatccacaa tggttaacgg atcgagcatt cgccctgggc cgatatcacc
    36241 acaagcctga ctgccgctgt ctggccccca gatgagcaaa ccacgggaag caagcacctc
    36301 taaattatgc tgcgtggcag cggcacggta catctgctgg ttcatggcgg ggagcacggc
    36361 tacaggcgca ggtgtagcca gacaaatcgt cgataccagg tcattcgcca ttccggcagc
    36421 aacacgggca atcaaatctg ccgtggcagg ggcgagaatc actaaatcag cccatttacc
    36481 cagctcaata tggcccatag cggcttcggc tgccgggtcc agcagactgt cggaaacggg
    36541 ataaccagaa accgcctgca agctaagtgg ggtgataaag gcttttgccg cttcggtcat
    36601 ggctacgcgg acgtcggccc cgcgatcgcg caaacgacgc accagttcag gggttttata
    36661 ggcagcaata ccgccgctga cgccgagaac gattttttta ccggccaggc tcatgatgat
    36721 ttttcctgtt gggtgacacc agaagttggc gattttatca caatactttt gttgtcgtgc
    36781 cttcacctga gaatcacttt gcgaggcgct ttccaggatt gaaaactggc cgtcgattta
    36841 acggaacggc tatgacagga tgcgagcacc acaaaggagg tgaaggtgaa aaacaatgca
    36901 cagctgttga tgccgcgcga aaaaatgctg aagtttggta ttagcgcctt aacggatgtc
    36961 gagctgctgg cgctatttct gcgtaccgga acgcgcggta aagatgtatt aaccctggca
    37021 aaagagatgc tggagaattt cggctctctt tatggcttgt taacctctga atatgaacag
    37081 tttagtggcg ttcatggaat tggcgtggcg aaattcgccc agttaaaggg gattgccgaa
    37141 ctggcgcggc gttactacaa cgtgcggatg cgtgaagaaa gccctttact cagcccggag
    37201 atgacgaggg aatttttaca aagccagctt acgggcgagg agcgggagat ctttatggtg
    37261 atctttctcg actcacaaca ccgggttata acgcatagcc gtcttttttc cggcacgcta
    37321 aaccatgttg aagtccatcc tcgggaaatt atccgcgaag cgataaaaat aaatgcctcg
    37381 gcgctgatcc ttgcacataa tcacccttcg ggttgtgctg aacccagtaa agcggataaa
    37441 ctcattactg aacggataat aaagagttgt cagttcatgg atttacgcgt gctcgaccat
    37501 atcgtaattg ggcgtggaga gtatgtttct tttgccgaac gcggctggat ttaacccgct
    37561 atgcgcgatc cttcgggatc tttgtctgtt cgggacttga gcacatcgct gagtcagcgt
    37621 atactacgcc acctttgaga atctcgggtt tggcatttgg gcctggcaat cgagagttca
    37681 catagaactg cgatgaccgg gctgtaaagc ctgacgaggc gccaataccc catacgaagc
    37741 tcgagctaat ttgatttttg gagaatagac atgtcccgag tctgccaagt tactggcaag
    37801 cgtccggtga ccggtaacaa ccgttcccac gcactgaacg cgactaaacg ccgtttcctg
    37861 ccgaacctgc actctcaccg tttctgggtt gagagcgaga agcgttttgt caccctgcgc
    37921 gtatctgcta aaggtatgcg tgtaatcgat aaaaaaggca tcgatacagt tctggctgaa
    37981 ctgcgtgccc gtggcgaaaa gtactaagta cttagaggaa ataaatcatg gctaaaggta
    38041 ttcgtgagaa aatcaagctg gtttcttctg ctggtactgg tcacttctat accactacga
    38101 agaacaaacg tactaagccg gaaaaactgg aactgaaaaa attcgatcca gttgttcgcc
    38161 agcacgtgat ctacaaagaa gcgaaaatca aataattctc gctttgatgt aacgaaaaac
    38221 ctcgctccgg cggggttttt tgttatctgc ttgcccccat attgactgca tctgttcatt
    38281 cctggagatg ctatgcctga attacccgaa gttgaaacca gccgtcgcgg catagaaccg
    38341 catctcgttg gtgcaaccat tcttcatgcg gtggtgcgca acggacgctt gcgctggccg
    38401 gtttcagaag agatctaccg tttaagcgac caaccagtgc ttagcgtgca gcggcgggct
    38461 aaatatctgc tgctggagct gcctgagggc tggattatca ttcatttggg gatgtctggc
    38521 agcctgcgca tccttccaga agaacttccc cctgaaaagc atgaccatgt tgatttggtg
    38581 atgagcaacg gtaaagtgct gcgctacacc gatccgcgcc gctttggtgc ctggctgtgg
    38641 accaaagagc tggaagggca caacgtgctg gcccatcttg gaccggagcc gcttagcgac
    38701 gatttcaacg gtgagtacct gcatcagaag tgcgcgaaga aaaaaacggc gattaaacca
    38761 tggctgatgg ataacaagct ggtggtaggc gtagggaata tctatgccag cgaatctctg
    38821 tttgctgcgg ggatccatcc ggatcggctg gcgtcatcac tgtcgctggc agagtgtgaa
    38881 ttgttagctc gggtgattaa agcggtgttg ctgcgttcga ttgagcaggg tggtacaacg
    38941 ctgaaagatt ttctgcaaag tgatggtaaa ccgggctatt tcgcgcagga attgcaggtt
    39001 tacgggcgaa aaggcgagcc gtgtcgggtg tgcggtacgc caattgtggc gactaaacat
    39061 gcgcagcggg caacgtttta ttgtcggcag tgccagaagt aattgatgcg agccggatgg
    39121 cataccatcc ggcataaacg ctacgctaac ttcgccatca gcgcctgatg gacattctcc
    39181 ggcaggaaat gggtgacatc gccctgatgg cgcgccacct ctttcaccaa cgatgaagag
    39241 ataaacgacc actctttcga cggcatcaga aacacacttt ccagttccgg cattaagtgg
    39301 cgattcatat gcgccagctg catttcatat tcaaaatccg ccaccgcacg caggccacga
    39361 atcagcaccg tagcgtgttg attccgggcg aagttcgcca tcaaatcact aaacccgacc
    39421 acttccacgt tccccagatg cgcggttgcc tgctgtgcca gcgccacacg ctcttccaga
    39481 gtaaacatcg gttttttact ggggctggca gcaatcgcca gaataacgtg atcgaacatt
    39541 tgcgtggcgc gcgtcacgat atcgatatga ccattggtaa tgggatcgaa agtacccgga
    39601 taaatcgccc gtttttgcat aacaacctca atgcgttttc ggtggcaggt aaggttccag
    39661 cagttgaagc agacgctgta gtgcgccctg gttttgatac agcacttcaa cggcatgacg
    39721 gccatagaaa ctacggtaat cggcgtcggt gagtaaagag gaaacctctt ttgcaagcgt
    39781 agtggcatcg gtaacggtaa tcagcccgct tgcctgctcc agccgcgcgc aaatgtcttt
    39841 aaagttaaac gtatgcggcc ccatcaatac cggaatagcg tgtgcggccg cttccagcgg
    39901 attatgccca ccacgttcaa ccagtgaacc gccaacaaag gcgagatcgg caatgccgta
    39961 cagtaacatc aactcgccca tcgtatcgcc aaccacaacc tgcgtgctgg tggaggggac
    40021 ttcccctgaa gatcgtgtga tatagcttag tccagcctgg cggacaaggt taatcgcatc
    40081 cgggaagcgt tccggatgac ggggtaccag gatgagcaat aaattcggga attgctgtaa
    40141 caatgcctga tgtgcggcga tcaccacact ctcttcgcct tcgtgagtgc tggtggcaat
    40201 ccataccggg cggtgtggtg cccactggcg gcgcagcgtc actgctttag cagccagttg
    40261 cggcgttaca gaaatatcga atttcaggct accggtgacg gtcacctgat tattttttgc
    40321 gcccagtgat acaaaacgtg caccatcttc ttcattttgc gcagcaatca gcgtaatacg
    40381 acgcagcaag cgacggacga atttacccag tttggcataa cctgcggccg agcgggcaga
    40441 gagtctcgcg ttagcgatca ccagcggaat tttacgttta tgtagcgccg caatcaggtt
    40501 aggccatagt tcggtttcca taatcaacac cagtttaggg tcgactttat tcaggaaacg
    40561 attaagcgca tcgggcaggt cgtacggcag ataaacgtgc tgaacatcct tcccgaaagc
    40621 cgattgtacg cgctccgaac cggttggcgt catggttgta acggtaatcg gtaaatcagg
    40681 ataacgatgg cgcagcgcgc gcaccaacgg gatcgccgcc agagtttcac cgacggagac
    40741 ggagtgcagc ataatgccgc ctggttttag cggatggcgg taaaaaccgt aacgttcacc
    40801 ccagcgtttt cgataggccg gagccttacg tccgcgcacc cagagccgta tccagatcag
    40861 cggctgaata aggtagagaa gggcggtgta aagcaattcg agcatagtaa atagctgact
    40921 tatggatgtg ctggggattc tatgtattta gctgtggctt taccattact tttcccgttt
    40981 ttgacttaaa tagcaattta cccgccaatt cttgctgaac atctatactt tttttgtatt
    41041 tttatgcgat tcattgattt ctgcagtacg tgcaggaagg aatcgcagag caacagtaaa
    41101 agaatatggt tgctaatgat tttatttgat tgatttcttt attgaaaatc aacaatgtgc
    41161 ttaaaaatca ttcgggtcgg attgccgcga aagaagtgat acactagcgc gtcaatatca
    41221 gtgcggtatc agtattcagg tagctgttga gcctggggcg gtagcgtgct ttttctgctt
    41281 caccttaatc ggataatctc aacaaaaaga gttacttgtg gataagccat ttcgaagaat
    41341 tttgctcatt aagatgcgtt ttcatgggga tatgttatta actactcccg tcattagttc
    41401 gctgaaaaaa aattaccctg acgcaaaaat cgatgtgctg ctttatcagg acaccatccc
    41461 gatcctgtct gaaaatccag agattaacgc gctctacggc ataaaaaata aaaaagcaaa
    41521 agcctcagaa aaaattgcca actttttcca tctcatcaag atattacgtg ccaataagta
    41581 tgaccttatc gttaatctta ccgatcaatg gatggttgct atactggttc gcttattaaa
    41641 tgcccgtgtg aaaatttccc aggattatca tcatcggcag tctgcttttt ggcgtaatag
    41701 tttcactcat ttggtgccgt tgcagggtgg aaatgtggtg gaaagtaact tatccgtgct
    41761 gacgccattg ggacttgaat cgttggtgaa gcagacaacc atgagttacc cgcctgcaag
    41821 ctggaaacgt atgcgtcgcg aacttgatca cgctggtgtt ggacaaaatt atgtggttat
    41881 ccaacctacg gcgcggcaaa tcttcaaatg ctgggacaac gccaagtttt ccgctgtgat
    41941 tgatgcctta catgctcgtg gttatgaagt cgttctgacg tccggcccag ataaagacga
    42001 tctggcctgc gtcaatgaaa ttgcgcaggg atgccagacg ccaccagtaa cggcactggc
    42061 cggaaaggtg accttcccgg aacttggtgc gttaatcgat catgcgcagc tgtttattgg
    42121 cgttgattcc gcaccggcgc atattgccgc tgcagttaat acgccactga tatcgctgtt
    42181 tggtgcgaca gaccatattt tctggcgtcc ctggtcaaat aacatgattc aattctgggc
    42241 gggagattac cgggaaatgc caacgcgcga tcagcgtgac cgaaatgaga tgtatctttc
    42301 ggttattccg gcggcagatg tcattgcagc tgtcgataaa ttacttccct cctccacgac
    42361 aggtacgtcg ttatgatcgt tgctttttgt ttatataaat attttccctt tggcggtttg
    42421 cagcgcgatt ttatgcgtat tgctcagaca gttgccgccc gaggtcatca tgttcgggtt
    42481 tatacccagt cgtgggaagg cgaatgccct gatgtatttg aactgatcaa agtgccggtt
    42541 aaatcgcata ccaatcacgg gcgcaatgcg gaatattttg cctgggtgca aaaacattta
    42601 cgtgaatacc ccgtcgatag agtcgttgga tttaataaaa tgccggggct ggacgtttat
    42661 tatgccgctg atgtttgtta tgccgagaaa gtagcgcagg agaaaggctt tttctatcgc
    42721 ctgacgtcac gttatcgcca ttatgccgcc tttgagcggg caaccttcga acagggcaag
    42781 ccgacacagc tgctgatgct gacagataag caaatcgccg atttccagaa acattatcag
    42841 actgaagcgg agcgttttca tattctgcca ccggggattt atcctgatcg taaatatagc
    42901 cagcaaccag cgaatagccg tgaaatcttc cgtaagaaga atggaataac cgaacaacaa
    42961 tatttattgt tgcaggtcgg ttcagacttc acgcgtaaag gtgtcgatcg ttccattgaa
    43021 gcacttgctt cgttaccgga ttcgctgcgc cacaacacat tactatatgt tgttgggcag
    43081 gataaaccgc gaaaatttga ggcgctggca gaaaaacgcg gcgtgcgcag taatgttcac
    43141 ttcttctcgg ggcgcaacga tgtctcggaa ttaatggcgg cggcggattt attacttcat
    43201 cctgcctacc aggaagcggc gggaattgtg ctgctggaag cgattactgc aggattaccg
    43261 gtactaacaa cagccgtttg tggctatgcg cattatattg ttgacgccaa ttgcggcgag
    43321 gctattgctg agccattccg ccaggaaaca ttgaatgaga ttttacgcaa agcgttaacg
    43381 caatcttcat tgcgccaggc ctgggcagaa aatgcgcgac attatgctga tacacaagat
    43441 ttatacagtc tgccagagaa agcagcggac atcataacgg gtggtctgga tggttgaact
    43501 taaagagccg tttgccacgt tatggcgcgg taaagatcct tttgaggaag ttaaaacctt
    43561 gcagggtgag gtatttcgtg aactggaaac tcgccgcact ctgcgctttg aaatggcggg
    43621 caaaagctat tttctcaaat ggcatcgcgg cacgaccctg aaagagataa tcaaaaattt
    43681 actctcattg cggatgccag tattaggcgc agaccgcgaa tggaatgcga ttcatcgact
    43741 gcgggatgtc ggcgttgata ctatgtatgg ggtggcattc ggcgaaaaag gcattaatcc
    43801 gctgaccaga acctcgttta ttattaccga agatctgaca ccaaccatca gtctggaaga
    43861 ttactgtgct gactgggcga ccaacccacc agatgttcgc gtaaagcgta tgcttattaa
    43921 gcgtgtcgcg acgatggtgc gcgatatgca tgctgcgggc attaaccacc gtgactgtta
    43981 tatctgtcat ttcctgctgc acttgccttt ttccggtaag gaagaggagt taaaaatttc
    44041 agtaattgac ctgcaccggg cgcagcttcg cacgcgcgtt ccacgtcgtt ggcgcgataa
    44101 agatcttatt gggctttatt tttcttcgat gaatatcggc ctgactcagc gggatatctg
    44161 gcggtttatg aaagtgtatt ttgtcgcccc gcttaaagac attctcaagc aggaacaagg
    44221 gctgctgtcg caagcagaag aaaaagccac aaaaatcagg gaaagaacga ttcgaaaatc
    44281 gttgtaattt ccggagagaa atatgagtgc ccactatttt aatccacaag agatgatcaa
    44341 taagacaatc atcttcgatg aaaggccagc ggcgtcagtg gcatcatcat tccatgttgc
    44401 ttatggcatt gataaaaact ttctttttgg ttgtggtgtt tcaatcacgt cagttttgtt
    44461 acataacaac gacgtgagtt ttgttttcca cgtttttatt gatgatatcc ctgaagccga
    44521 tatccagcgt ttagcccaat tggcgaaaag ctatcgtacc tgtatccaga tccatctggt
    44581 aaattgtgaa cggcttaagg cattaccgac gaccaaaaat tggtctattg ccatgtattt
    44641 ccgttttgta attgcagatt actttattga tcaacaagat aagatccttt acctggatgc
    44701 tgatatcgcc tgtcagggaa acttaaagcc gctgataaca atggatcttg ccaataacgt
    44761 tgctgctgtt gttactgaac gcgatgctaa ctggtggtcg ttacggggtc aaagtctgca
    44821 gtgtaatgaa cttgaaaagg gttactttaa ttcaggtgtc ctgttaatta atacactagc
    44881 gtgggcgcag gagtccgttt ctgctaaagc gatgtcgatg cttgctgata aagccatcgt
    44941 ttcccgttta acctatatgg atcaagatat ccttaatctt atcctgttag ggaaagttaa
    45001 actcattgat gctaaataca atacgcagtt tagtttaaat tatgaattaa aaa
//
LOCUS       DADXDL010000029        43267 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.029, whole genome shotgun sequence.
ACCESSION   DADXDL010000029 DADXDL010000000
VERSION     DADXDL010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 43267)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 43267)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..43267
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.029"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..96
                     /locus_tag="IRB70_001910"
     CDS             <1..96
                     /locus_tag="IRB70_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0631827.1"
                     /translation="LPAVKLYISYNKASLNNLVFSRFIDRLNDSF"
     gene            243..1463
                     /locus_tag="IRB70_001911"
     CDS             243..1463
                     /locus_tag="IRB70_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HBC0631828.1"
                     /translation="MSIYKIPLPLNILEAAKERITWTLNTLPRVCVSFSGGKDSGLML
                     HLTAEIARQMGKKICVLFIDWEAQFSCTINYVQSLREFYADVIEEFYWVALPLTTQNS
                     LSQYQPEWQCWEPDVEWVRQPPQDAITDPDFFSFYQPGMTFEQFVREFAEWFSQKRPA
                     AMMIGIRADESYNRFVAIASLNKQRFADDKPWTTAAPGGHSWYIYPIYDWKVADIWTW
                     YANHQQLCNPLYNIMYQAGVPLRHMRICEPFGPEQRQGLWLYHVIEPDRWAAMCARVS
                     GVKSGGIYAGHDNHFYGHRKILKPEHLDWQEYALLLLNSMPEKTAEHYRNKIAIYLHW
                     YQKKGIEVPQTQQGDIGAKDIPSWRRICKVLLNNDYWCRALSFSPTKAKNYQRYNERI
                     KGKRQEWGILCNND"
     gene            1436..2065
                     /locus_tag="IRB70_001912"
     CDS             1436..2065
                     /locus_tag="IRB70_001912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB-like nuclease domain-containing protein"
                     /protein_id="HBC0631829.1"
                     /translation="MGDTMQQRLTQDLTQFLASLPEDDRIKAINEIRMAIHQVSPFRE
                     EPVDCVLWVKNSQLMPNDYNPNNVAPPEKKLLKKSIEIDGFTQPIVVTHTDKNALEIV
                     DGFHRHEIGKGSSSLKLRLKGYLPVTCLEGTRNQRIAATIRHNRARGRHQITAMSEIV
                     RELSQLGWDDNKIGKELGMDSDEVLRLKQINGLQELFADRQFSRAWTVK"
     gene            complement(2066..3226)
                     /gene="ybdL"
                     /locus_tag="IRB70_001913"
     CDS             complement(2066..3226)
                     /gene="ybdL"
                     /locus_tag="IRB70_001913"
                     /EC_number="2.6.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine-oxo-acid transaminase"
                     /protein_id="HBC0631830.1"
                     /translation="MTNNPLIPQSKLPQLGTTIFTQMSALAQQHQAINLSQGFPDFDG
                     PRYLQERLAYHVAQGANQYAPMTGVQALREAIAQKTERLYGYQPDADSDITVTAGATE
                     ALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHFRVDWQEFAALL
                     SERTRLVILNTPHNPSATVWQQTDFAALWQAIAGHEIFVISDEVYEHINFSQQGHASV
                     LAHPQLRERAVAVSSFGKTYHMTGWKVGYCVAPAPISAEIRKVHQYLTFSVNTPAQLA
                     LADMLRAEPEHYLALPDFYRQKRDILVNALNESRLEILPCEGTYFLLVDYSAVSTLDD
                     VEFCQWLTREHGVAAIPLSVFCADPFPHKLIRLCFAKKESTLLAAAERLRQL"
     gene            3335..4423
                     /gene="hcxA"
                     /locus_tag="IRB70_001914"
     CDS             3335..4423
                     /gene="hcxA"
                     /locus_tag="IRB70_001914"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxycarboxylate dehydrogenase HcxA"
                     /protein_id="HBC0631831.1"
                     /translation="MPHNPIRVVVGPANYFSHPGSFNHLHDFFTDEQLSRAVWIYGER
                     AIAAAQTKLPPAFELPGAKHILFRGHCSESDVQQLAAESADDRNVVIGVGGGALLDTA
                     KALARRLGLPFVAVPTIAATCAAWTPLSVWYNDAGQALHYEIFDDANFMVLVEPEIIL
                     NAPQQYLLAGIGDTLAKWYEAVVLAPQPETLPLTVRLGINNAQAIRDVLLNSSEQALS
                     DQQNHQLTQSFCDVVDAIIAGGGMVGGLGDRFTRVAAAHAVHNGLTVLPQTEKFLHGT
                     KVAYGILVQSALLGQDDVLAQLTGAYQRFHLPTTLAELEVDINNQAEIDKVIAHTLRP
                     VESIHYLPVTLTPDTLRAAFEKVESFKA"
     gene            complement(4433..4630)
                     /locus_tag="IRB70_001915"
     CDS             complement(4433..4630)
                     /locus_tag="IRB70_001915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HBC0631832.1"
                     /translation="MFDSLAKAGKYLGQAAKLMIGMPDYDNYVEHMRVNHPDQTPMTY
                     EEFFRERQDARYGGKGGARCC"
     gene            complement(4774..6879)
                     /gene="cstA"
                     /locus_tag="IRB70_001916"
     CDS             complement(4774..6879)
                     /gene="cstA"
                     /locus_tag="IRB70_001916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation protein CstA"
                     /protein_id="HBC0631833.1"
                     /translation="MNKSGKYLVWTVLSVMGAFALGYIALNRGEQINALWIVVASVCI
                     YLIAYRFYGLYIAKNVLAVDPTRMTPAVRHNDGLDYVPTDKKVLFGHHFAAIAGAGPL
                     VGPVLAAQMGYLPGMIWLLAGVVLAGAVQDFMVLFVSTRRDGRSLGELVKEEMGPTAG
                     VIALVACFMIMVIILAVLAMIVVKALTHSPWGTYTVAFTIPLALFMGIYLRYLRPGRI
                     GEVSVIGLVFLIFAIISGGWVAESPTWAPYFDFTGVQLTWMLVGYGFVAAVLPVWLLL
                     APRDYLSTFLKIGTIVGLAVGILIMRPTLTMPALTKFVDGTGPVWTGNLFPFLFITIA
                     CGAVSGFHALISSGTTPKMLANEGQACFIGYGGMLMESFVAIMALVSACIIDPGVYFA
                     MNSPMAVLAPAGTADVVASAAQVVSSWGFAITPDTLNQIASEVGEQSIISRAGGAPTL
                     AVGMAYILHGALGGMMDVAFWYHFAILFEALFILTAVDAGTRAARFMLQDLLGVVSPG
                     LKRTDSLPANLLATALCVLAWGYFLHQGVVDPLGGINTLWPLFGIANQMLAGMALMLC
                     AVVLFKMKRQRYAWVALVPTAWLLICTLTAGWQKAFSLDAKVGFLAIANKFQAMIDSG
                     NIPSQYTESQLAQLVFNNRLDAGLTIFFMVVVVVLALFSIKTALAALKEPKPTAKETP
                     YEPMPENVEEIVAQAKGAH"
     gene            complement(7060..7473)
                     /gene="entH"
                     /locus_tag="IRB70_001917"
     CDS             complement(7060..7473)
                     /gene="entH"
                     /locus_tag="IRB70_001917"
                     /EC_number="3.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proofreading thioesterase EntH"
                     /protein_id="HBC0631834.1"
                     /translation="MIWKRHLTLDELNATSDNTMVAHLGIVYTRLGDDVLEAEMPVDT
                     RTHQPFGLLHGGASAALAETLGSMAGFMMTRDGQCVVGTELNATHHRPVSEGKVRGVC
                     QPLHLGRQNQSWEIVVFDEQGRRCCTCRLGTAVLG"
     gene            complement(7476..8222)
                     /gene="entA"
                     /locus_tag="IRB70_001918"
     CDS             complement(7476..8222)
                     /gene="entA"
                     /locus_tag="IRB70_001918"
                     /EC_number="1.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
                     EntA"
                     /protein_id="HBC0631835.1"
                     /translation="MDFSGKNVWVTGAGKGIGYATALAFVEAGAKVTGFDQAFAQEQY
                     PFATEVMDVADAAQVAQVCQRLLAETERLDVLVNAAGILRMGATDQLSKEDWQQTFAV
                     NVGGAFNLFQQTMNQFRRQRGGAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGL
                     ELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIARPQEI
                     ANTILFLASDLASHITLQDIVVDGGSTLGA"
     gene            complement(8222..9079)
                     /gene="entB"
                     /locus_tag="IRB70_001919"
     CDS             complement(8222..9079)
                     /gene="entB"
                     /locus_tag="IRB70_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis bifunctional
                     isochorismatase/aryl carrier protein EntB"
                     /protein_id="HBC0631836.1"
                     /translation="MAIPKLQAYALPESHDIPKNKVDWAFEPQRAALLIHDMQDYFVS
                     FWGENCPMMEQVIANIAALRDYCKQHNIPVYYTAQPKEQSDEDRALLNDMWGPGLTRS
                     PEQQKVVDRLTPDADDTVLVKWRYSAFHRSPLEQMLKESGRNQLIITGVYAHIGCMTT
                     ATDAFMRDIKPFMVADALADFSRDEHLMSLKYVAGRSGRVVMTEELLPAPIPASKAAL
                     REVILPLLDESDEPFDDDNLIDYGLDSVRMMALAARWRKVHSDIDFVMLAKNPTIDAW
                     WKLLSREVK"
     gene            complement(9093..10703)
                     /gene="entE"
                     /locus_tag="IRB70_001920"
     CDS             complement(9093..10703)
                     /gene="entE"
                     /locus_tag="IRB70_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(2,3-dihydroxybenzoyl)adenylate synthase EntE"
                     /protein_id="HBC0631837.1"
                     /translation="MSIPFTRWPEEFACRYREKGYWQDLPLTDILTRHAASDSIAVID
                     GERQLSYRELNQAADNLACSLRRQGIKPGETALVQLGNVAELYITFFALLKLGVAPVL
                     ALFSHQRSELNAYASQIEPALLIADRQHALFSGDDFLNTFVAGHSSIRVVQLHNDSGE
                     HNLQDAINHPAEDFTATPSPADEVAYFQLSGGTTGTPKLIPRTHNDYYYSVRRSVEIC
                     QFTQQTRYLCAIPAAHNYAMSSPGSLGVFLAGGTVVLAADPSATLCFPLIEKHQVNVT
                     ALVPPAVSLWLQALTEGESRTQLASLKLLQVGGARLSATLAARIPVEIGCQLQQVFGM
                     AEGLVNYTRLDDSAEKIIHTQGYPMCPDDEVWVADAEGNPLPQGEVGRLMTRGPYTFR
                     GYYKSPQHNASAFDANGFYCSGDLISIDPEGYITVQGREKDQINRGGEKIAAEEIENL
                     LLRHPAVIYAALVSMEDELMGEKSCAYLVVKEPLRAVQVRRFLREQGIAEFKLPDRVE
                     CVDSLPLTAVGKVDKKQLRQWLASRASA"
     gene            complement(10713..11888)
                     /gene="entC"
                     /locus_tag="IRB70_001921"
     CDS             complement(10713..11888)
                     /gene="entC"
                     /locus_tag="IRB70_001921"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase EntC"
                     /protein_id="HBC0631838.1"
                     /translation="MDTSLAEEVQQTMATLAPNRFFFMSPYRSFTTSGCFARFDEPAV
                     NGDSPDSPFQQKLAALFADAKAQGIKNPVMVGAIPFDPRQPSSLYIPESWQSFSRQEK
                     QASARRFTRSQSLNVVERQAIPEQATFEQMVARAAALTATPQVDKVVLSRLIDITTDA
                     AIDSGVLLERLIAQNPVSYNFHVPLADGGVLLGASPELLLRKDGERFSSIPLAGSARR
                     QPDEVLDREAGNRLLASEKDRHEHELVTQAMKEVLRERSSELHVPSSPQLITTPTLWH
                     LATPFEGKANLQENALTLACLLHPTPALSGFPHQAATQVIAELEPFDRELFGGIVGWC
                     DSEGNGEWVVTIRCAKLRENQVRLFAGAGIVPASSPLGEWRETGVKLSTMLNVFGLH"
     gene            12077..13033
                     /gene="fepB"
                     /locus_tag="IRB70_001922"
     CDS             12077..13033
                     /gene="fepB"
                     /locus_tag="IRB70_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe2+-enterobactin ABC transporter
                     substrate-binding protein"
                     /protein_id="HBC0631839.1"
                     /translation="MRLAPLYRNALLLTGLLLSGIVAVQAADWPRQITDSRGTHTLES
                     QPQRIVSTSVTLTGSLLAIDAPVIASGATTPNNRVADDQGFLRQWSKVAKERKLQRIY
                     IGEPSAEAVAAQMPDLILISATGGDSALALYDQLSTIAPTLIINYDDKSWQSLLTQLG
                     EITGHEKQAAERIAQFDKQLAAAKEQIKLPPQPVTAIVYTAAAHSANLWTPESAQGQM
                     LEQLGFTLAKLPAGLNASQSQGKRHDIIQLGGENLAAGLNGDSLFLFAGDQKDADAIY
                     ANPLLAHLPAVQNKQVYALGTETFRLDYYSAMQVLERLKALF"
     gene            complement(13037..14287)
                     /gene="entS"
                     /locus_tag="IRB70_001923"
     CDS             complement(13037..14287)
                     /gene="entS"
                     /locus_tag="IRB70_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin transporter EntS"
                     /protein_id="HBC0631840.1"
                     /translation="MNKQSWLLNLSLLKTHPAFRAVFLARFISIVSLGLLGVAVPVQI
                     QMMTHSTWQVGLSVTLTGGAMFVGLMVGGVLADRYERKKVILLARGTCGIGFIGLCLN
                     ALLPEPSLLAIYLLGLWDGFFASLGVTALLAATPALVGRENLMQAGAITMLTVRLGSV
                     ISPMIGGLLLATGGVAWNYGLAAAGTFITLLPLLSLPALPPPPQPREHPLKSLLAGFR
                     FLLASPLVGGIALLGGLLTMASAVRVLYPALADNWQMSAAQIGFLYAAIPLGAAIGAL
                     TSGKLAHSARPGLLMLLSTLGSFLAIGLFGLMPMWILGVVCLALFGWLSAVSSLLQYT
                     MLQTQTPEAMLGRINGLWTAQNVTGDAIGAALLGGLGAMMTPVASASASGFGLLIIGV
                     LLLLVLVELRRFRQTPPQMTASDS"
     gene            14398..15402
                     /gene="fepD"
                     /locus_tag="IRB70_001924"
     CDS             14398..15402
                     /gene="fepD"
                     /locus_tag="IRB70_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-siderophore ABC transporter permease"
                     /protein_id="HBC0631841.1"
                     /translation="MSGSVAVTRAIAVPGLLLLLIIATALSLLIGAKSLPASVVLEAL
                     SGTCQSADCTIVLDARLPRTLAGLLAGGALGLAGALMQTLTRNPLADPGLLGVNAGAS
                     FAIVLGAALFGYSSAQEQLAMAFAGALVASLIVAFTGSQGGGQLSPVRLTLAGVALAA
                     VLEGLTSGIALLNPDVYDQLRFWQAGSLDIRNLYTLKVVLIPVLIAGATALLLSRALN
                     SLSLGSDTATALGSRVARTQLIGLLAITVLCGSATAVVGPIAFIGLMMPHMARWLVGA
                     DHRWSLPVTLLATPALLLFADIIGRVIVPGELRVSVVSAFIGAPVLIFLVRRKTRGGA
                     "
     gene            15399..16391
                     /gene="fepG"
                     /locus_tag="IRB70_001925"
     CDS             15399..16391
                     /gene="fepG"
                     /locus_tag="IRB70_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter permease"
                     /protein_id="HBC0631842.1"
                     /translation="MIYVSRRLIITCLLLITACVVAGIWGLRSGTVTLETSQVFAALM
                     GDAPRSMTMVVTEWRLPRVLMALLIGAALGVSGAIFQSLMRNPLGSPDVMGFNTGAWS
                     GVLVAMVLFGQDLTAIALAAMVGGIVTSLLVWLLAWRNGIDTFRLIIIGIGVRAMLVA
                     FNTWLLLKASLETALTAGLWNAGSLNGLTWAKTSPSAPIIILMLIAAALLVRRMRLLE
                     MGDDTACALGVSVERSRLLMMLVAVVLTAAATALAGPISFIALVAPHIARRISGTARW
                     GLTQAALCGALLLLAADLCAQQLFMPYQLPVGVVTVSLGGIYLIVLLIQESRKK"
     gene            16388..17203
                     /gene="fepC"
                     /locus_tag="IRB70_001926"
     CDS             16388..17203
                     /gene="fepC"
                     /locus_tag="IRB70_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-enterobactin ABC transporter ATP-binding
                     protein"
                     /protein_id="HBC0631843.1"
                     /translation="MTESVARLRGEQLTLGYGKYTVAENLTVEIPDGHFTAIIGPNGC
                     GKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVARRIGLLAQNATTPGDITVQELV
                     ARGRYPHQPLFTRWRKEDEDAVTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ
                     ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALR
                     EGKIVAQGAPKEIVTAELIERIYGLRCMIIDDPVAGTPLVVPLGRTAPSTAKI"
     gene            complement(17200..18333)
                     /gene="fepE"
                     /locus_tag="IRB70_001927"
     CDS             complement(17200..18333)
                     /gene="fepE"
                     /locus_tag="IRB70_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS O-antigen length regulator"
                     /protein_id="HBC0631844.1"
                     /translation="MSSLNIKQGSDAHFPEYPLASPSNNEIDLLNLIDVLWRAKKTVM
                     AVVFAFACTGLLISFILPQKWTSAAVVTPPEPVQWQELEKTFTKLRVLDLDIKIDRTE
                     VFNLFIKKFQSVSLLEEYLRSSPYVMDQLKEAKIDELDLHRAIVALSEKMKAVDDNAS
                     KKKDEPSLYTSWTLSFTAPTSEEAQTVLSGYIDYISALVVKESIENVRNKLEIKTQFE
                     KEKLAQDRIKTKNQLDANIQRLNYSLDIANAAGIKKPVYSNGQAVKDDPDFSISLGAD
                     GIERKLEIEKAVTDVAELNGELRNRQYLVEQLTKANINDVNFTPFKYQLSPSLPVKKD
                     GPGKAIIVILSAMIGGMVACGGVLLRHAMASRKQDAVMEEHLV"
     gene            complement(18548..22429)
                     /gene="entF"
                     /locus_tag="IRB70_001928"
     CDS             complement(18548..22429)
                     /gene="entF"
                     /locus_tag="IRB70_001928"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin non-ribosomal peptide synthetase
                     EntF"
                     /protein_id="HBC0631845.1"
                     /translation="MSQHLPLVAAQPGIWMAEKLSDLPSAWSVAHYVELTGEVDAPLL
                     ARAVVAGLAQADTLRMRFTEDNGEVWQWVDDALTFELPEIIDLRTNIDPHGTAQALMQ
                     ADLQQDLRVDSGKPLVFHQLIQVADNRWYWYQRYHHLLVDGFSFPAITRQIANIYCAW
                     LRGEPTPASPFTPFADVVEEYQQYRESEAWQRDAAFWAEQRRQLPPPASLSPAPLPGR
                     SASADILRLKLEFTDGEFRQLATQLSGVQRTDLALALAALWLGRLCNRMDYAAGFIFM
                     RRLGSAALTATGPVLNVLPLGIHIAAQETLPELATRLAAQLKKMRRHQRYDAEQIVRD
                     SGRAAGDEPLFGPVLNIKVFDYQLDIPDVQAQTHTLATGPVNDLELALFPDEHGDLSI
                     EILANKQRYDEPTLIQHAERLKMLIAQFAADPALLCGDVDIMLPGEYAQLAQINATQV
                     EIPETTLSALVAEQAAKTPDAPALVDARYQFSYREMREQVVALANLLRERGVKPGDSV
                     AVALPRSVFLTLALHAIVEAGAAWLPLDTGYPDDRLKMMLEDARPSLLITTDDQLPRF
                     ADVPDLTRLCYNAPLIPQGSAPLQLSQPHHTAYIIFTSGSTGRPKGVMVGQTAIVNRL
                     LWMQNHYPLTGEDVVAQKTPCSFDVSVWEFFWPFIAGAKLVMAEPEAHRDPLAMQQFF
                     AEYGVTTTHFVPSMLAAFVASMTPQTARQSCATLKQVFCSGEALPADLCREWQQLTGA
                     PLHNLYGPTEAAVDVSWYPAFGEELAQVRGSSVPIGYPVWNTGLRILDAMMHPVPPGV
                     AGDLYLTGIQLAQGYLGRPDLTASRFIADPFAPGERMYRTGDVARWLDNGAVEYLGRS
                     DDQLKIRGQRIELGEIDRVMQALPDVEQAVTHACVINQAAATGGDARQLVGYLVSQSG
                     LPLDTSALQAQLRETLPPHMVPVVLLQLPQLPLSANGKLDRKALPLPELKAQAPGRAP
                     KAGSETIIAAAFSSLLGCDVQDADADFFALGGHSLLAMKLAAQLSRQFARQVTPGQVM
                     VASTVAKLATIIDGEEDSTQRMGFETILPLREGNGPTLFCFHPASGFAWQFSVLSRYL
                     DPQWSIIGIQSPRPHGPMQTAANLDEVCEAHLATLLEHQPHGPYYLLGYSLGGTLAQG
                     IAARLRARGEQVAFLGLLDTWPPETQNWQEKEANGLDPEVLAEINREREAFLAAQQGS
                     TSTELFTTIEGNYADAVRLLTTAHSVPFEGKATLFVAERTLQEGMNPERAWSPWITEL
                     DIYRQDCAHVDIISPMAFEKIGPIIRATLNK"
     gene            complement(22426..22644)
                     /gene="ybdZ"
                     /locus_tag="IRB70_001929"
     CDS             complement(22426..22644)
                     /gene="ybdZ"
                     /locus_tag="IRB70_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin biosynthesis protein YbdZ"
                     /protein_id="HBC0631846.1"
                     /translation="MAFSNPFDDPQGAFYILRNAQGQFSLWPQQCLLPAGWDIVCQPQ
                     SQESCQQWLEVHWRTLTPANFTQLQEAQ"
     gene            complement(22647..23849)
                     /gene="fes"
                     /locus_tag="IRB70_001930"
     CDS             complement(22647..23849)
                     /gene="fes"
                     /locus_tag="IRB70_001930"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415117.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterochelin esterase"
                     /protein_id="HBC0631847.1"
                     /translation="MTALKVGSESWWQSKHGPEWQRLNDEMFEVTFWWRDPQGSEEYS
                     TIKRVWVYITGVTDHHQNSQPQSMQRIAGTNVWQWTTQLNANWRGSYCFIPTERDDIF
                     SAPSPDRLELREGWRKLLPQAIADPLNPQSWKGGRGHAVSALEMPQAPLQPGWDCPQA
                     PETPAKEIIWKSERLKNSRRVWIFITGDATAEERPLAVLLDGEFWAQSMPVWPALTSL
                     THRRQLPPAVYVLIDAIDTTHRAHELPCNADFWLAVQQELLPLVKAIASFSDRADRTV
                     VAGQSFGGLSALYAGLHWPERFGCVLSQSGSYWWPHRGGQQEGALLEQLKAGQVSAEG
                     LRIVLEAGIREPMIMQANQALYAQLHPIKESIFWRQVDGGHDALCWRGGLMQGLIDLW
                     QPLFHDRS"
     gene            24092..26332
                     /gene="fepA"
                     /locus_tag="IRB70_001931"
     CDS             24092..26332
                     /gene="fepA"
                     /locus_tag="IRB70_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore enterobactin receptor FepA"
                     /protein_id="HBC0631848.1"
                     /translation="MNKKIHSLALLVNLGIYGVAQAQEPTDTPVSHDDTIVVTAAEQN
                     LQAPGVSTITADEIRKNPVARDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRGMGPE
                     NTLILIDGKPVSSRNSVRQGWRGERDTRGDTSWVPPEMIERIEVLRGPAAARYGNGAA
                     GGVVNIITKKGSGEWHGSWDAYFNAPEHKEEGATKRTNFSLTGPLGDEFSFRLYGNLD
                     KTQADAWDINQGHQSARAGTYATTLPAGREGVINKDINGVVRWDFAPLQSLELEAGYS
                     RQGNLYAGDTQNTNSDAYTRSKYGDETNRLYRQNYSLTWNGGWDNGVTTSNWVQYEHT
                     RNSRIPEGLAGGTEGKFNEKATQDFVDIDLDDVMLHSEVNLPIDFLVNQTLTLGTEWN
                     QQRMKDLSSNTQALTGTNTGGAIDGVSATDRSPYSKAEIFSLFAENNMELTDSTIVTP
                     GLRFDHHSIVGNNWSPALNISQGLGDDFTLKMGIARAYKAPSLYQTNPNYILYSKGQG
                     CYASAGGCYLQGNDDLKAETSINKEIGLEFKRDGWLAGVTWFRNDYRNKIEAGYVAVG
                     QNAVGTDLYQWDNVPKAVVEGLEGSLNVPVSETVMWTNNITYMLKSENKTTGDRLSII
                     PEYTLNSTLSWQAREDLSMQTTFTWYGKQQPKKYNYKGQPAVGPETKEISPYSIVGLS
                     ATWDVTKNVSLTGGVDNLFDKRLWRAGNAQTTGDLAGANYIAGAGAYTYNEPGRTWYM
                     SVNTHF"
     gene            26507..27127
                     /gene="entD"
                     /locus_tag="IRB70_001932"
     CDS             26507..27127
                     /gene="entD"
                     /locus_tag="IRB70_001932"
                     /EC_number="6.3.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enterobactin synthase subunit EntD"
                     /protein_id="HBC0631849.1"
                     /translation="MKTTHTALPFVGHTLHFVEFDPASFCEQDLLWLPHYAQLQHAGR
                     KRKTEHLAGRIAAVYALREYGYKCVPAIGELRQPVWPAGVYGSISHCGTTALAVVSRQ
                     PIGIDIEEIFSVQTARELTDNIITPAEHERLAECGLTFSLALTLAFSAKESAFKASKI
                     QAAQGFLDYQIISWNKQQIIIRLEDEQFAVHWQIKEKIVITLCQHD"
     gene            27293..28405
                     /locus_tag="IRB70_001933"
     CDS             27293..28405
                     /locus_tag="IRB70_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element IS421 family transposase"
                     /protein_id="HBC0631850.1"
                     /translation="MNYSHDNWSAILAHIGKPEELDTSARNAGALTRRREIRDAATLL
                     RLGLAYGPGGMSLREVTAWAQLHDVATLSDVALLKRLRNAADWFGILAAQTLAVRAAV
                     TGCTSGKRLRLVDGTAISAPGGGSAEWRLHMGYDPHTCQFTDFELTDSRDAERLDRFA
                     QTADEIRIADRGFGSRPECIRSLAFGEADYIVRVHWRGLRWLTAEGMRFDMMGFLRGL
                     DCGKNGETTVMIGNSGNKKAGAPFPARLIAVSLPPEKALISKTRLLSENRRKGRVVQA
                     ETLEAAGHVLLLTSLPEDEYSAEQVADCYRLRWQIELAFKRLKSLLHLDALRAKEPEL
                     AKAWIFANLLAAFLIDDIIQPSLDFPPRSAGSEKKN"
     gene            complement(28598..28750)
                     /gene="hokE"
                     /locus_tag="IRB70_001934"
     CDS             complement(28598..28750)
                     /gene="hokE"
                     /locus_tag="IRB70_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308648.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokE"
                     /protein_id="HBC0631851.1"
                     /translation="MLTKYALVAVIVLCLTVLGFTLLVGDSLCEFTVKERNIEFKAVL
                     AYEPKK"
     gene            29202..30320
                     /locus_tag="IRB70_001935"
     CDS             29202..30320
                     /locus_tag="IRB70_001935"
                     /EC_number="6.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--cysteine ligase"
                     /protein_id="HBC0631852.1"
                     /translation="MPLPDFHVSEPFTLGIELEMQVVNPPGYDLSQDSSMLIDAVKNK
                     ITAGEVKHDITESMLELATDVCRDINQAAGQFSAMQKVVLQAAADHHLEICGGGTHPF
                     QKWQRQEVCDNERYQRTLENFGYLIQQATVFGQHVHVGCASGDDAIYLLHGLSRFVPH
                     FIALSAASPYMQGTDTRFASSRPNIFSAFPDNGPMPWVSNWQQFEALFRCLSYTTMID
                     SIKDLHWDIRPSPHFGTVEVRVMDTPLTLSHAVNMAGLIQATAHWLLTERPFKNQEKD
                     YLLYKFNRFQACRYGLEGVITDPHTGDRRPLTEDTLRLLEKIAPSANKIGASSAIEAL
                     HRQVVSGLNEAQLMRDFVADGGSLIGLVKKHCEIWAGD"
     gene            30386..30634
                     /locus_tag="IRB70_001936"
     CDS             30386..30634
                     /locus_tag="IRB70_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1158 domain-containing protein"
                     /protein_id="HBC0631853.1"
                     /translation="MKHPLETLTTAAGILLMAFLSCLLLPAPALGLTLAQKLVTTFHL
                     MDLSQLYTLLFCLWFLVLGAIEYFVLRFIWRRWFSLAD"
     gene            30699..31082
                     /locus_tag="IRB70_001937"
     CDS             30699..31082
                     /locus_tag="IRB70_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000360941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBC0631854.1"
                     /translation="MDKQSLHETAKRLALELPFVELCWPFGPEFDVFKIGGKIFMLSS
                     ELRGVPFINLKSDPQKSLLNQQIYPSIKPGYHMNKKHWISVYPGEEISEALLRDLIND
                     SWNLVVDGLAKRDQKRVRPDSTVNQ"
     gene            31161..31814
                     /gene="nfsB"
                     /locus_tag="IRB70_001938"
     CDS             31161..31814
                     /gene="nfsB"
                     /locus_tag="IRB70_001938"
                     /EC_number="1.5.1.34"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-insensitive NAD(P)H nitroreductase"
                     /protein_id="HBC0631855.1"
                     /translation="MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQ
                     PWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDAWLKLVVDQE
                     DADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLD
                     AVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV"
     gene            31922..33169
                     /gene="ybdG"
                     /locus_tag="IRB70_001939"
     CDS             31922..33169
                     /gene="ybdG"
                     /locus_tag="IRB70_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel YbdG"
                     /protein_id="HBC0631856.1"
                     /translation="MQDLISQVEDLAGIEIDHTTSMVMIFGIIFLTAVVVHIFLHWVV
                     LRTFEKRAIASSRLWLQIITQNKLFHRLAFTLQGIIVNIQAVFWLQKGTEAADILTTC
                     AQLWIMMYALLSVFSLLDVILNLAQKFPAASQLPLKGIFQGIKLIGAILVGILMISLL
                     IGQSPAILISGLGAMAAVLMLVFKDPILGLVAGIQLSANDMLKLGDWLEMPKYGADGA
                     VIDIGLTTVKVRNWDNTITTIPTWSLVSDSFKNWSGMSASGGRRIKRSISIDVTSIRF
                     LDEDEMQRLNKAHLLKPYLTSRHKEINEWNRQQGSTESVLNLRRMTNIGTFRAYLNEY
                     LRNHPRIRKDMTLMVRQLAPGDNGLPLEIYAFTNTVVWLEYESIQADIFDHIFAIVEE
                     FGLRLHQSPTGNDIRSLAGAFKQ"
     gene            complement(33237..34613)
                     /gene="pheP"
                     /locus_tag="IRB70_001940"
     CDS             complement(33237..34613)
                     /gene="pheP"
                     /locus_tag="IRB70_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine transporter"
                     /protein_id="HBC0631857.1"
                     /translation="MKNASTVSEDTASNQEPTLHRGLHNRHIQLIALGGAIGTGLFLG
                     IGPAIQMAGPAVLLGYGVAGIIAFLIMRQLGEMVVEEPVSGSFAHFAYKYWGPFAGFL
                     SGWNYWVMFVLVGMAELTAAGIYMQYWFPDVPTWIWAAAFFIIINAVNLVNVRLYGET
                     EFWFALIKVLAIIGMIGFGLWLLFSGHGGEKASIDNLWRYGGFFATGWNGLILSLAVI
                     MFSFGGLELIGITAAEARAPEKSIPKAVNQVVYRILLFYIGSLVVLLALYPWVEVKSN
                     SSPFVMIFHNLDSNVVASALNFVILVASLSVYNSGVYSNSRMLFGLSVQGNAPKFLTR
                     VSRRGVPINSLMLSGAITSLVVLINYLLPQKAFGLLMALVVATLLLNWIMICLAHLRF
                     RAAMRRQGRETQFKALLYPFGNYLCIAFLGMILLLMCTMDDMRLSAILLPVWIVFLFV
                     AFKTLRRK"
     gene            complement(34715..37858)
                     /gene="cusA"
                     /locus_tag="IRB70_001941"
     CDS             complement(34715..37858)
                     /gene="cusA"
                     /locus_tag="IRB70_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter permease
                     subunit CusA"
                     /protein_id="HBC0631858.1"
                     /translation="MIEWIIRRSVANRFLVLMGALFLSIWGTWTIINTPVDALPDLSD
                     VQVIIKTSYPGQAPQIVENQVTYPLTTTMLSVPGAKTVRGFSQFGDSYVYVIFEDGTD
                     PYWARSRVLEYLNQVQGKLPAGVSAELGPDATGVGWIYEYALVDRSGKHDLADLRSLQ
                     DWFLKYELKTIPDVAEVASVGGVVKEYQVVIDPQRLAQYGISLAEVKSALDASNQEAG
                     GSSIELAEAEYMVRASGYLQTLDDFNHIVLKASENGVPVYLRDVAKVQVGPEMRRGIT
                     ELNGEGEVAGGVVILRSGKNAREVIAAVKDKLETLKSSLPEGVEIVTTYDRSQLIDRA
                     IDNLSGKLLEEFIVVAVVCALFLWHVRSALVAIISLPLGLCIAFIVMHFQGLNANIMS
                     LGGIAIAVGAMVDAAIVMIENAHKRLEEWQHQHPDATLDNKTRWQVITDASVEVGPAL
                     FISLLIITLSFIPIFTLEGQEGRLFGPLAFTKTYAMAGAALLAIVVIPILMGYWIRGK
                     IPPESSNPLNRFLIRVYHPLLLKVLHWPKTTLLVAALSVLTVLWPLNKVGGEFLPQIN
                     EGDLLYMPSTLPGISAAEAASMLQKTDKLIMSVPEVARVFGKTGKAETATDSAPLEMV
                     ETTIQLKPQDQWRPGMTMDKIIEELDNTVRLPGLANLWVPPIRNRIDMLSTGIKSPIG
                     IKVSGTVLADIDTMAEQIEEVARTVPGVASALAERLEGGRYINVEINREKAARYGMTV
                     ADVQLFVKSAVGGAMVGETVEGIARYPINLRYPQSWRDSPQALRQLPILTPMKQQITL
                     ADVADVKVSTGPSMLKTENARPTSWIYIDARDRDMVSVVHDLQKAIAEKVQLKPGTSV
                     AFSGQFELLERANHKLKLMVPMTLMIIFVLLYLAFRRVGEALLIISSVPFALVGGIWL
                     LWWMGFHLSVATGTGFIALAGVAAEFGVVMLMYLRHAIEAEPSLNNPQTFSEQKLDEA
                     LYHGAVLRVRPKAMTVAVIIAGLLPILWGTGAGSEVMSRIAAPMIGGMITAPLLSLFI
                     IPAAYKLMWLHRHRVRK"
     gene            complement(37870..39093)
                     /gene="cusB"
                     /locus_tag="IRB70_001942"
     CDS             complement(37870..39093)
                     /gene="cusB"
                     /locus_tag="IRB70_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     adaptor subunit CusB"
                     /protein_id="HBC0631859.1"
                     /translation="MKKIALIIGSMIAGGIISAAGFTWFAKAEPPAEKTPTAERKILF
                     WYDPMYPNTRFDKPGKSPFMDMDLVPKYADEESSASGVRIDPTQTQNLGVKTATVTRG
                     PLTFAQSFPANVSYNEYQYAIVQARAAGFIDKVYPLTVGDKVQKGTPLLDLTIPDWVE
                     AQSEYLLLRETGGTATQTEGILERLRLAGMPEADIRRLIATQKIQTRFTLKAPIDGVI
                     TAFDLRAGMNIAKDNVVAKIQGMDPVWVTAAIPESIAWLVKDASQFTLTVPARPDKTL
                     TIRKWTLLPGVDAATRTLQLRLEVDNADEALKPGMNAWLQLNTASEPMLLIPSQALID
                     TGNEQRVITVDADGRFVPKRVAVFQASQGVTALRSGLAEGEKVVSSGLFLIDSEANIS
                     GALERMRSESATHAY"
     gene            complement(39109..39441)
                     /gene="cusF"
                     /locus_tag="IRB70_001943"
     CDS             complement(39109..39441)
                     /gene="cusF"
                     /locus_tag="IRB70_001943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter periplasmic
                     metallochaperone CusF"
                     /protein_id="HBC0631860.1"
                     /translation="MKKALQVAMFSLFTVIGFNAQANEHHHETMSEAQPQVISATGVV
                     KGVDLESKKITIHHDPIAAVNWPEMTMRFTITPQTKMSEIKTGDKVAFNFVQQGNLSL
                     LQDIKVSQ"
     gene            complement(39465..40847)
                     /gene="cusC"
                     /locus_tag="IRB70_001944"
     CDS             complement(39465..40847)
                     /gene="cusC"
                     /locus_tag="IRB70_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) efflux RND transporter outer
                     membrane channel CusC"
                     /protein_id="HBC0631861.1"
                     /translation="MSPCKLLPFCVALALTGCSLAPDYQRPAMPVPQQFSLSQNGLVN
                     AADNYQNAGWRTFFVDNQVKTLISEALVNNRDLRMAALKVQEARAQYRLTDADRYPQL
                     NGEGSGSWSGNLKGNTATTREFSTGLNASFDLDFFGRLKNMSEAERQNYLATEEAQRA
                     VHILLVSNVAQSYFNQQLAYAQVQIAEETLRNYQQSYAFVEKQLLTGSSNVLALEQAR
                     GVIESTRSDIAKRQGELAQANNALQLLLGSYGKLPQAQTVNSDSLQSVKLPAGLSSQI
                     LLQRPDIMEAEHALMAANANIGAARAAFFPSISLTSGISTASSDLSSLFNASSGMWNF
                     IPKIEIPIFNAGRNQANLDIAEIRQQQSVVNYEQKIQNAFKEVADALALRQSLNDQIS
                     AQQRYLASLKITLQRARALYQHGAVSYLEVLDAERSLFATRQTLLDLNYARQVNEISL
                     YTALGGGWQQ"
     gene            41004..41687
                     /gene="cusR"
                     /locus_tag="IRB70_001945"
     CDS             41004..41687
                     /gene="cusR"
                     /locus_tag="IRB70_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper response regulator transcription factor
                     CusR"
                     /protein_id="HBC0631862.1"
                     /translation="MKLLIVEDEKKTGEYLTKGLTEAGFVVDLADNGLNGYHLAMTGD
                     YDLIILDIMLPDVNGWDIVRMLRSANKGMPILLLTALGTIEHRVKGLELGADDYLVKP
                     FAFAELLARVRTLLRRGAAVIIESQFQVADLMVDLVSRKVTRSGTRITLTSKEFTLLE
                     FFLRHQGEVLPRSLIASQVWDMNFDSDTNAIDVAVKRLRGKIDNDFEPKLIQTVRGVG
                     YMLEVPDGQ"
     gene            41677..43125
                     /gene="cusS"
                     /locus_tag="IRB70_001946"
     CDS             41677..43125
                     /gene="cusS"
                     /locus_tag="IRB70_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cu(+)/Ag(+) sensor histidine kinase CusS"
                     /protein_id="HBC0631863.1"
                     /translation="MVSKPFQRPFSLATRLTFFISLATIAAFFAFAWIMIHSVKVHFA
                     EQDINDLKEISATLERVLNHPDETQARRLMTLEDIVSGYSNVLISLADSHGKTVYHSP
                     GAPDIREFTRDAIPDKDAQGGEVYLLSGPTIMMPGHGHGHMEHSNWRMINLPVGPLVD
                     GKPIYTLYIALSIDFHLHYINDLMNKLIMTASIISILIVFIVLLAVHKGHAPIRSVSR
                     QIQNITSKDLDVRLDPQTVPIELEQLVLSFNHMIERIEDVFTRQSNFSADIAHEIRTP
                     ITNLITQTEIALSQSRSQKELEDVLYSNLEELTRMAKMVSDMLFLAQADNNQLIPEKK
                     MLNLADEVGKVFDFFEALAEDRGVELRFVGDECQVAGDPLMLRRALSNLLSNALRYTP
                     PGEAIVVRCQTVDHQVQVSVENPGTPIAPEHLPRLFDRFYRVDPSRQRKGEGSGIGLA
                     IVKSIVVAHKGTVAVTSDARGTRFMIKLPEKG"
BASE COUNT        10360 a        11931 c        11040 g         9936 t
ORIGIN      
        1 cttcctgcgg ttaaacttta tatttcctat aacaaggctt cgttgaacaa ccttgtcttc
       61 tcccgattca tagatcgttt aaatgatagc ttctgattca ttaccactgg caaataatat
      121 attacgcatc aattaattca ttatgtgaat ataaaataat gtgctctatc ttgcttcgtt
      181 tatcctataa ttagcggatt catctcacga gtcaccccgt aacgttcaga gagcgttttt
      241 agatgtctat ttataaaatc ccgcttccac tgaatattct ggaagctgca aaagaacgta
      301 ttacctggac acttaatacc ctaccccgtg tctgcgtttc tttttcgggt ggtaaagatt
      361 ccggattaat gctgcatctg accgccgaaa ttgcccgaca aatgggcaaa aaaatctgcg
      421 ttttgtttat cgactgggaa gcgcagttct catgcactat taactatgtt cagtcattac
      481 gtgagtttta cgccgatgtc atcgaagagt tttactgggt tgcgctcccg cttacgacgc
      541 aaaattccct ttctcaatac caacccgaat ggcagtgctg ggaacctgat gtcgaatggg
      601 tgcgtcagcc cccgcaagat gcgataaccg atcctgactt tttctccttt taccagcctg
      661 gcatgacctt cgaacaattt gtgcgtgagt ttgctgaatg gttttcacaa aaacgtccgg
      721 cggcgatgat gatcggcatc cgtgcagatg agtcctacaa ccgttttgtc gccatcgcca
      781 gtttaaataa acaacgtttt gccgatgata agccctggac caccgccgca ccaggcggtc
      841 atagttggta catttacccc atctacgact ggaaagtggc tgatatctgg acctggtatg
      901 ctaaccatca acagctctgt aacccactgt ataatataat gtatcaggca ggcgttcctc
      961 tgcgtcatat gcgaatttgc gaaccttttg gcccggagca acggcaagga ttatggctct
     1021 atcacgttat cgaaccggat cgctgggctg ctatgtgcgc acgagtcagc ggggtaaaaa
     1081 gtggcggcat ttacgccgga catgataatc atttttatgg tcatcggaaa atcctcaagc
     1141 cagaacattt agactggcaa gaatatgcat tattgctgct caatagcatg ccggaaaaaa
     1201 cagctgagca ttaccgcaat aaaatcgcca tttatttgca ctggtatcag aaaaaaggca
     1261 tcgaagttcc acaaacccag caaggggaca ttggcgcgaa agatatcccc tcctggcggc
     1321 gaatatgcaa agttttactc aataacgatt actggtgccg ggcattatca tttagtccta
     1381 cgaaagcgaa gaactatcag cgttataacg aacggataaa aggaaaacgt caggaatggg
     1441 ggatactatg caacaacgat taacgcagga tttaacccaa tttctcgcca gcttgccgga
     1501 agatgatcgc atcaaagcga ttaatgaaat ccgcatggcg atccatcagg ttagcccctt
     1561 tcgtgaagag ccagtggatt gcgttctgtg ggttaaaaac agccaactta tgcctaatga
     1621 ttacaaccca aacaacgtgg caccacccga aaaaaaactg ctgaaaaaat ccattgaaat
     1681 agatggtttt acccaaccca ttgtggtcac gcatacggat aaaaatgccc tggaaatcgt
     1741 ggatggtttt caccgccatg aaattggtaa aggctcatca tcgttaaaat tacgcttaaa
     1801 aggttatttg ccggtgacct gtctggaagg tacgcgtaat caacgcatcg ccgcaactat
     1861 tcgtcataat cgcgctcgtg gacgtcacca aatcactgcc atgtcagaaa tcgtccgaga
     1921 actcagccag ttgggatggg acgataataa aattggcaaa gagctgggaa tggacagcga
     1981 cgaagtgttg cgcctgaagc aaattaacgg cctgcaagag ttgtttgccg accgtcaatt
     2041 ttcccgcgcc tggacggtta aataactaaa gctggcgcag gcgttctgct gctgccagca
     2101 acgtcgattc cttcttggca aaacagagac gaatcagttt atgtgggaag ggatcggcgc
     2161 aaaacaccga cagcggaatc gccgctacgc cgtgctcccg cgtcagccac tggcaaaact
     2221 caacatcatc cagcgtagat acggcgctgt aatccaccag caaaaagtat gtaccttcgc
     2281 acggtaaaat ctccagccga ctttcattta aggcattcac cagaatatcg cgcttctggc
     2341 gataaaagtc cggtaacgca agataatgct caggttctgc acgtagcata tccgcaagtg
     2401 ccagctgtgc cggggtattc accgaaaagg tcagatactg gtgtaccttg cgaatttcgg
     2461 cactgatggg cgctggcgca acgcaataac ccactttcca gccggtcata tgataggtct
     2521 tgccaaacga tgacaccgcc accgcccgct cacgcagctg cggatgcgcc agtacgctgg
     2581 catggccctg ttgtgaaaag ttgatgtgct cgtaaacttc atcgctaatg acaaaaatct
     2641 cgtgcccggc aatcgcctgc cacagagcgg cgaaatcagt ctgctgccag acagttgcac
     2701 tggggttatg cggggtgttg aggatcacca gtcgggtgcg ctcgcttaac aatgcggcaa
     2761 attcctgcca gtccacgcga aaatgcggtg gttgcagtgc catacgcttc actattcccc
     2821 cagaaagcgc gatggcgggc gcgtaactgt catagctggg atcaaagcaa atcacttcat
     2881 cgccattgcg aaccaatgca gtaatcgctg cgtatagcgc ttccgtcgcc cctgctgtta
     2941 cggtgatatc gctgtcggca tctggttgat agccatacag ccgttccgtt ttctgagcaa
     3001 tcgcctcgcg taatgcttgc acgccggtca tgggtgcgta ttggtttgcc ccctgggcaa
     3061 cgtggtacgc cagccgttcc tgcaaatagc gcggaccatc aaaatcagga aagccttgcg
     3121 acaggttaat cgcctggtgt tgctgcgcca gtgcactcat ctgggtgaaa atagtggtgc
     3181 caagttgtgg aagtttgctt tgtggaatca gagggttatt tgtcattttt attgtgcctg
     3241 atgaagttgc gtgttgaagg cactataaca cgatgctagt atttggcaat caagacgttt
     3301 agatgtctaa ataaaacaat aaggacaaca caacatgcct cacaatccta tccgcgtggt
     3361 cgtcggcccg gctaactact tttcacatcc aggaagtttc aatcacctgc acgatttttt
     3421 cactgatgaa cagctttctc gcgcggtgtg gatctacggc gaacgcgcca ttgctgcggc
     3481 gcaaaccaaa ctgccgccag cgtttgaact gccaggggca aagcatattt tgtttcgtgg
     3541 tcattgcagc gaaagcgatg tacagcaact ggcggctgaa tccgctgacg atcgcaacgt
     3601 ggtgattggc gtcggcggcg gcgcactgct cgacaccgcg aaagccctcg cccgccgtct
     3661 cggtctgcca tttgttgccg ttccgacgat cgccgctacc tgcgccgcct ggacaccgct
     3721 ctctgtctgg tataacgatg ccggacaggc gctgcattat gagattttcg acgacgccaa
     3781 ttttatggtg ctggtggaac cggagattat cctcaacgcg ccgcaacaat atctgctggc
     3841 ggggatcggt gacacgctgg cgaaatggta tgaagcggtg gtgctggccc cgcaaccaga
     3901 aacgttgccg ctaaccgtgc gactggggat caataatgcg caggccattc gcgacgtctt
     3961 gttaaacagt agcgaacagg cgctgagcga tcagcaaaat caccagttaa cgcaatcatt
     4021 ttgcgatgtg gtggatgcca ttattgctgg tggtgggatg gttggtggtc tgggcgatcg
     4081 ttttacgcgt gtggcggcag ctcatgccgt gcataacggt ctgaccgtgc tgccgcaaac
     4141 cgagaagttt ctccacggca ccaaagtcgc ctacggaatt ctggtgcaaa gcgccttgct
     4201 gggtcaggat gatgtgctgg cgcaattaac tggagcgtat cagcgttttc atctgccgac
     4261 tacgctggcg gagctggaag tggatatcaa taatcaggcg gagatcgaca aagtgattgc
     4321 ccacacctta cgtccggtgg aatccattca ttacctgccg gtcacgctga caccggatac
     4381 gttgcgtgca gcgttcgaaa aagtggaatc gtttaaagcc tgacgtacag atttagcagc
     4441 agcgcgcgcc gccttttcca ccgtagcgcg cgtcctgccg ctcacggaaa aactcttcgt
     4501 aggtcatcgg cgtttgatcg ggatggttaa cccgcatatg ttcgacatag ttgtcgtaat
     4561 caggcatacc aatcatcagt ttcgccgcct gacctaaata ttttccggct tttgccagtg
     4621 aatcaaacat ctaaacctcc ggtaaacagg ttgctgagag ggtgctatca acgcgctcgg
     4681 tcagtcccct cgccccacag gagagagggt tagggtgagg gggaaccctc ggcaccatgc
     4741 caacattcgc caacatcccc cctcactctg actttagtgc gcgccttttg cctgcgccac
     4801 gatctcctcg acattttccg gcatcggctc atacggcgtt tctttcgccg ttggcttcgg
     4861 ctctttcaat gccgccagtg ccgtcttaat cgagaacagt gccagaacca ccacgaccac
     4921 cataaagaag atggttaacc cggcatccag acggttgttg aacaccagtt gcgccagctg
     4981 tgactcggta tactgcgacg gaatattgcc gctgtcgatc attgcctgga acttgttagc
     5041 aatcgccagg aagccgactt ttgcatccag gctaaacgct ttctgccagc ctgcggtcag
     5101 ggtacaaatc agcagccagg ccgttggtac cagcgccacc caggcgtaac gttgacgttt
     5161 cattttgaac agcaccacag cacagagcat cagcgccatc cctgccagca tctggttggc
     5221 aataccaaac agcggccaca gagtgttaat accgcccagc ggatcgacca cgccctgatg
     5281 gaggaagtag ccccacgcca gtacgcacag cgccgttgcc agcaggttag caggcagtga
     5341 atcggtccgt ttcaggcccg gagacaccac gcccagcaga tcctgcaaca taaagcgcgc
     5401 agcacgcgta cctgcatcca ccgccgtcag aataaacagt gcttcaaaca gaatggcgaa
     5461 gtgataccag aacgccacat ccatcatgcc gcccagcgca ccgtgcagaa tgtaggccat
     5521 ccccaccgcc agggtcggcg caccgcccgc acgggaaatg atcgactgtt cacccacttc
     5581 gctggcaatc tggtttagcg tatccggggt aatcgcaaag ccccagctac tcaccacctg
     5641 cgcggcagaa gcaaccacat ccgccgtccc tgccggagcc agcaccgcca tcgggctgtt
     5701 catggcgaag tacacacccg gatcgatgat acaggcggaa accagcgcca taatcgccac
     5761 gaaggattcc atcaacatcc caccgtagcc gataaagcac gcctgccctt cgttcgccag
     5821 catcttcggt gtagtgccgg aagagatcag tgcatggaag ccagacaccg cgccacaggc
     5881 gatggtgata aacaggaacg ggaacaggtt accggtccat accgggccag tgccatcgac
     5941 aaatttagtt agcgcaggca tggtcagcgt cgggcgcata atcagaatgc ctaccgccag
     6001 accgacgata gtcccgattt tcaggaaggt tgagaggtag tcgcgcgggg ccagcagcaa
     6061 ccacaccggc agcaccgccg ccacaaaacc gtagcccacc agcatccaag tcagctgcac
     6121 gccggtaaag tcaaagtacg gtgcccaggt cgggctttct gccacccagc cgccagagat
     6181 aatggcgaaa atcaggaaca ccagaccaat caccgacact tcgccaatac gccccggacg
     6241 caaatagcgc aggtagatcc ccataaacag cgccagcgga atggtgaacg caacggtata
     6301 cgttccccac gggctatgag tcagggcttt caccacgatc atcgccagca cggcaaggat
     6361 aatgaccatg atcataaagc aggccaccag cgctatcacc ccggcggttg gccccatctc
     6421 ttctttgacc agctcaccca gcgagcgacc gtcacggcgc gtagaaacaa acagcaccat
     6481 gaaatcctgc accgcaccgg cgagaaccac cccggcgagc agccagatca tccctggcag
     6541 gtaacccatt tgcgccgcca gtaccggccc caccagcggg ccagctccgg caatggccgc
     6601 aaaatggtga ccgaacagca ctttcttgtc cgtcggcaca tagtccagcc cgtcgttatg
     6661 gcgcaccgct ggcgtcatac gcgtcgggtc aaccgccagc acatttttgg cgatatacaa
     6721 cccataaaaa cggtaagcga tcagatagat acagaccgac gccaccacaa tccacagcgc
     6781 gttgatctgt tccccacgat ttaaagcaat gtatcccaga gcaaatgctc ccattacaga
     6841 gagcactgtc cagacgaggt atttccctga tttgttcata gttgttatcc gtgtgcgtgt
     6901 ccatagagat gttacatttt gtttctataa catctttgta caatttaaca acacagcaac
     6961 catgtaaatc agagttgaaa ccaatattta acttaacaat gttaactcga tcactccgtt
     7021 aaccgcgttt tcctgcaatc tcatttaatt ctgtcgggct catcccaaaa ctgccgtacc
     7081 cagccgacaa gtgcagcaac gccgcccctg ttcatcgaaa acgacgattt cccagctctg
     7141 attttgtcgt ccaagatgca gcggctggca gacaccgcgc acctttccct cagacaccgg
     7201 gcgatgatgt gtggcgttaa gttccgtgcc caccacacac tgtccgtcgc gggtcatcat
     7261 aaatccggcc atcgatccca gcgtttccgc cagcgccgcc gacgcgccgc catgcagcag
     7321 gccaaacggc tgatgagtac gggtatcaac cggcatttcg gcttccagca catcatcgcc
     7381 cagacgggta tacacaattc ccagatgcgc caccattgtg ttatcgctgg tggcgttcag
     7441 ctcgtcgagc gttaaatggc gtttccagat catgcttatg cccccagcgt agagccgcca
     7501 tcgaccacaa tatcctgtag ggtgatatgg ctggcgaggt cagaggcgag gaacaaaatc
     7561 gtgttggcga tctcttgtgg acgggcgatt ttccccagcg gaatgccgag tttaaactgc
     7621 tcgccaaagc cgcgaatacg ctgctcttcg gcgtcatcgc tcacccacag cgtgcgttgc
     7681 atatcggtgt cggtggagcc tggcgaaacc acattacagc gcacgccgct acccgccagt
     7741 tccagcccaa cgctcaacgc caggcttttc agcgccgctt tcgacgcgcc ataagcactc
     7801 ataccaatgc gcggcgtgtg tgcggcgtcg gacgcaacag taacaatcgc cccgccccgc
     7861 tgacggcgaa actggttcat ggtctgctgg aacaggttaa acgcaccgcc gacattgacc
     7921 gcaaaagtct gctgccagtc ctccttactg agctgatcgg tcgcgcccat gcgcaaaatt
     7981 cccgccgcat tgaccagcac gtccagtcgc tccgtttcag ctaacagtcg ctgacatacc
     8041 tgcgccacct gcgcagcatc ggcaacatcc atcacttcgg tcgcaaaggg atattgctcc
     8101 tgagcgaacg cttgatcaaa accggtgact ttcgctcccg cctcaacaaa cgccagcgcc
     8161 gtggcgtagc cgataccttt ccctgcgcca gttacccaga catttttacc gctgaaatcc
     8221 attatttcac ctcgcgggaa agtagcttcc accaggcgtc gatggtcggg tttttcgcca
     8281 gcatgacaaa gtcgatatcg ctatgcactt tgcgccagcg cgccgccagc gccatcatcc
     8341 gcaccgaatc cagaccgtag tcgatcaggt tgtcatcatc gaacggttca tcggactcgt
     8401 ccagcaacgg caggatcacc tcacgcagcg ccgctttgct ggcggggata ggtgctggca
     8461 gcaattcttc ggtcatcacc acccggccag aacgtccggc cacatatttc agcgacatca
     8521 aatgctcgtc acggctgaaa tcggccagcg catctgccac cataaacggt ttaatatcgc
     8581 gcataaatgc gtccgttgcg gtggtcatac agccaatgtg ggcatatacc ccggtaataa
     8641 tcagctggtt acgtccactc tctttcagca tttgctccag cggggaacga tgaaacgcgc
     8701 tgtagcgcca cttcaccagc accgtgtcgt cggcatctgg cgtcaggcga tccaccacct
     8761 tttgctgttc cggcgaacgg gtcaggcctg gcccccacat atcattcaac agcgcccgat
     8821 cttcatcgct ctgctctttc ggctgggcgg tgtaataaac cgggatattg tgctgtttgc
     8881 agtagtcgcg tagtgccgca atattcgcga tcacctgctc catcatcggg cagttctcgc
     8941 cccagaagct gacaaaatag tcctgcatat catggattaa caacgcggca cgttgcggtt
     9001 caaaggccca gtcgacttta ttcttaggaa tatcgtgaga ctccggcagt gcgtaagcct
     9061 gtaattttgg aatagccatc gtgttctctc cttcaggctg atgcgcgtga cgccagccac
     9121 tgacgtaatt gttttttatc gactttcccg accgccgtca gcggaagtga atccacacac
     9181 tccacgcgat ccggtaattt aaattcggca ataccctgtt cacgcaggaa acgacgcacc
     9241 tgcaccgcgc gcagcggctc ttttaccacc agataagcac agcttttttc gcccatcagc
     9301 tcatcttcca tgctcaccag tgcggcgtag atcaccgccg gatggcgcag cagcaggttt
     9361 tcgatctctt cggcagcgat cttctcgccg ccacggttga tctgatcttt ctcgcgcccc
     9421 tgcacagtga tgtaaccctc tggatcaata gagatcagat cgccggaaca gtaaaaaccg
     9481 ttggcatcaa aggcgctggc attgtgctgc gggcttttgt aatagccacg gaaggtgtac
     9541 ggaccgcggg tcatcaggcg tccaacttcc ccttgcggca gtggatttcc ttcggcatcg
     9601 gcaacccaca cttcatcgtc cggacacatt gggtaaccct gggtatggat aattttctcc
     9661 gcgctatcat caagtcgggt gtagttcacc agcccttccg ccataccgaa cacctgctgt
     9721 aactggcagc caatctctac gggaatacgc gctgccagcg tggcagaaag acgggcgccg
     9781 ccgacctgta acagtttcag ggaagcaagc tgcgtccggc tttcaccttc ggtcagcgct
     9841 tgtaaccaca ggctgactgc tggtggcacc agcgcggtga cgttcacctg atgtttttca
     9901 atcaatggga agcaaagcgt ggcgctgggg tcggcagcca gaacgacagt gccgccagcg
     9961 agaaataccc ccaacgatcc cggtgaactc atggcgtagt tatgagccgc cgggatcgcg
    10021 cacaggtagc gcgtctgttg tgtgaactga caaatctcga cgctacgacg cacgctgtag
    10081 taatagtcat tatgagtgcg tgggatgagt ttcggtgtgc cggtggttcc gccggaaagc
    10141 tggaaatagg ccacttcatc agcaggagat ggcgtggcag taaaatcctc agccggatgg
    10201 ttaatcgcat cctgcaagtt atgctcaccg ctgtcgttgt gaagttgcac cacgcgaatg
    10261 gaagaatgcc ctgcaacaaa tgtgttgagg aaatcatccc cgctaaacag cgcatgttgg
    10321 cgatcggcaa tcagtaacgc cggttcaatc tggctggcgt aggcgttcag ttcactacgc
    10381 tgatggctga acagcgccag caccggcgca acgcccagtt tcagcagcgc gaaaaaggta
    10441 atatacaatt cagcgacgtt acccagctgt accagcgcgg tttcaccagg tttaatgccc
    10501 tgacggcgca aactacacgc gaggttatcc gccgcctgat tcagctcccg gtaactcaac
    10561 tgccgctcgc cgtcgataac cgcgatgctg tcactcgcag catgtcgcgt cagaatgtcg
    10621 gtcagcggca aatcctgcca gtagcctttt tcccgatagc gacaggcaaa ctcttccggc
    10681 cagcgggtaa atggaatgct catcctcgct ccttaatgca atccaaaaac gttcaacatg
    10741 gtagaaagtt tgacgcccgt ttcgcgccac tcacccaacg gtgacgacgc aggcacaatc
    10801 cccgctccgg caaacagacg cacctgattt tcccgcagct tcgcgcagcg gatggtcaca
    10861 acccattcgc cgttaccttc gctgtcacac caacccacaa tgccgccaaa cagttcgcgg
    10921 tcgaacggct ccagttcagc aataacctga gtcgcggcct gatgcgggaa accgctcaac
    10981 gcgggggtcg gatgcagcag acaggccaga gtcagtgcgt tttcttgcaa attcgcttta
    11041 ccttcaaagg gcgttgcgag atgccacagc gtcggcgtgg tgatcagttg tggagaggaa
    11101 ggaacgtgta actcactact gcgttcgcgc agtacctctt tcatcgcctg agtcaccagt
    11161 tcatgttcat ggcgatcttt ttctgacgcc agcagacgat tacccgcttc gcgatcgagc
    11221 acttcatccg gctgacgacg cgcggaaccg gctaacggaa tggagctaaa acgctcgccg
    11281 tctttacgta gcagcagttc cgggctggcc cccagcagaa cgccaccatc agccaacgga
    11341 acatggaagt tgtaactaac cgggttttgc gcaatcaacc gttccagcaa tacgccacta
    11401 tcaatggcgg cgtcagtggt gatatcaatc aaccgtgaca acaccacttt gtcgacctgc
    11461 ggcgtggcgg taagtgcggc agcacgggca accatctgtt caaacgtggc ttgttccgga
    11521 atggcctgac gttccaccac gttcagcgac tggctgcggg tgaaacggcg tgcggaagct
    11581 tgtttttcct gacgggagaa cgactgccag gattcgggaa tatacagcga cgaaggctga
    11641 cgtggatcga agggaatcgc cccgaccatc accggatttt tgatgccctg cgctttggca
    11701 tcggcaaaca gcgcggcgag tttttgctgg aagggactgt cgggcgaatc cccgttcaca
    11761 gccggttcat cgaagcgggc gaaacatcct gacgtcgtaa aactgcggta cggcgacata
    11821 aagaaaaagc gattgggcgc aagtgttgcc atggtctgct gtacttcctc agccagtgac
    11881 gtatccatat catcctccac aaaatgataa aggctttaat aatgattatc atttatattt
    11941 tcggtcgcta acctaaaagc aaacgcgcac tatgtcaact cttgaggtaa cgcaatctgc
    12001 aactcggggt tgcatctgtt tgtggttaca atgaaaatga gaagcattaa ctctattaat
    12061 aacaggaagc taatttgtga gactcgcccc gctctaccgc aacgcccttc tattaacagg
    12121 acttttgctt tcaggaatag tcgcagttca ggccgccgac tggccgcgtc agattactga
    12181 cagccggggc actcataccc tggaaagcca gccgcagcgt atagtttcca ccagcgtcac
    12241 cctgaccggc tcactgctgg cgattgatgc tccggtgatc gccagcggcg cgaccacgcc
    12301 aaataaccgc gtcgcggatg accagggctt tttacgccag tggagcaagg tggcgaaaga
    12361 acgcaaactg caacggatct atatcggcga accgagcgcc gaagccgttg ccgcgcaaat
    12421 gccggatctg attttaatta gcgcaaccgg cggcgattcg gcgctggcgc tgtacgatca
    12481 gctttctacc atcgccccaa cattaatcat caattacgac gacaaaagct ggcagtcgct
    12541 gttaacgcag cttggcgaaa ttaccgggca tgagaaacaa gcggcagagc ggattgcaca
    12601 gtttgataag caactggcgg cggcgaaaga gcaaatcaaa ttaccgccgc agccggtcac
    12661 tgccattgtc tataccgccg ctgcacacag tgccaatctc tggacgccgg aatcagcaca
    12721 agggcagatg ctggaacaac tcggctttac gttggcgaaa ttgcccgcag ggttaaacgc
    12781 cagccaaagc cagggcaaac gccatgacat cattcagctt ggtggagaaa atctggctgc
    12841 agggttaaat ggcgattcac tattcctgtt cgctggtgat cagaaagatg ccgatgcgat
    12901 ttatgccaat ccactgctcg cgcacctgcc tgcagtacaa aacaagcagg tttatgcgct
    12961 gggaaccgag acgttccgcc tggattacta cagcgccatg caagtgctgg aacgacttaa
    13021 ggcgctgttt taagcattaa ctgtcggacg ctgtcatctg cggcggcgtc tggcgaaaac
    13081 gtcgcaactc caccagcacc agcaataaca acacgccgat aatcaacaaa ccaaaaccgc
    13141 tcgcgcttgc ggaagcaacc ggtgtcatca tcgcgcccaa accgcccagc agcgctgcgc
    13201 ctatggcatc gcccgtcacg ttttgcgccg tccacaaacc gttaatccgc cctaacatcg
    13261 cttccggggt ttgcgtttgc agcattgtat attgcagcaa cgaactaacc gcgctcaacc
    13321 aaccgaacag cgccaggcaa accacgccta aaatccacat cggcatcagg ccaaacagac
    13381 caatggcaag gaacgatccc agcgtggaga gcagcatcaa taaccctggt cgcgcactat
    13441 gtgccagctt cccgctggtt aacgcgccaa tagccgcgcc gagcggaatc gccgcataga
    13501 gaaaaccaat ctgtgccgcc gacatctgcc agttgtcagc cagcgccgga tacaggaccc
    13561 gcaccgcgct cgccatcgtc aataaaccac ccagcaacgc aatccctccc accagcgggc
    13621 tggcgagtag aaaacgaaat cctgccagta atgatttcaa cggatgctca cgcggctgcg
    13681 gcggtggtgg caacgccgga aggcttaaca acggtagcaa ggtaataaac gtgcccgccg
    13741 ccgccagccc gtagttccag gctacgcctc cggtcgccag cagtaaaccg ccaatcatgg
    13801 gcgaaatcac cgatcccaga cgcacagtca acatggtgat cgccccggcc tgcattaggt
    13861 tttcacgccc taccagtgca ggtgtcgccg ccagtagcgc cgtaacgcca agtgatgcga
    13921 aaaaaccatc ccataaacca agtaaataga ttgccagcaa tgacggctcc ggcagcagcg
    13981 cgttcaggca cagtccaatg aagccaatgc cacaggtgcc gcgcgccagc aaaatcactt
    14041 ttttacgctc atagcgatcc gccagcacac cgccgaccat caggccaaca aacatcgcgc
    14101 cgccggtcag cgtcaccgaa agccccacct gccaggtaga atgcgtcatc atctggatct
    14161 gcaccggcac cgcgacgccg agcaaaccca gagacacaat tgagataaaa cgagcgagga
    14221 atactgcgcg aaacgccggg tgcgttttca acaggctgag gttaagcagc caggattgtt
    14281 tattcattac aatgccttgc catcaaatat tttaaatacc tattcttagg ctgcacatgc
    14341 taacatatcc aaataagatc gataacgata attaatttca ttatcatgga agttcgtatg
    14401 tctggttctg ttgccgtgac acgcgccatt gccgtgcccg gattgctgtt attactgatt
    14461 atcgcgacgg cattaagcct gctcattgga gcaaaatcac tccccgcttc cgtagtgctg
    14521 gaggccctct ccggcacctg ccagagcgcc gactgcacca tcgtgctcga cgcacgactg
    14581 ccgcgcaccc ttgccggttt actggccggc ggtgcgcttg gccttgccgg ggcgttgatg
    14641 caaaccctca cccgaaaccc acttgccgac cccggcttgc ttggcgtaaa cgccggagcc
    14701 agctttgcca ttgtgctggg tgcggcgctg tttggatact catccgcgca ggaacaactg
    14761 gcgatggcct tcgccggggc gctagtggcc tcgttgattg ttgcctttac cggcagccag
    14821 ggcggcgggc agttaagtcc ggtgcgttta accctggcgg gcgtggcgct ggcggcggtg
    14881 ctggaagggc tgaccagcgg catcgccctg cttaatcctg acgtctacga tcaactgcgt
    14941 ttctggcaag ccggttcgct ggatattcgc aatctatata ccttaaaagt tgtgctgatc
    15001 ccggtgctga tcgccggagc aaccgcgcta ttactgagcc gcgcgctgaa cagtttaagc
    15061 ctcggcagtg acaccgcgac ggcgctgggc agccgcgtgg cgcgcacaca gttgattggt
    15121 ctgctggcga ttaccgtgct ttgtggtagt gcgacggcgg tagttggccc gattgccttt
    15181 attggcctga tgatgccgca tatggcgcgc tggctggtag gtgccgatca tcgctggtcg
    15241 ctgcccgtca cgctacttgc cacccctgcc ctgctgctgt ttgccgatat catcgggcgg
    15301 gtgattgtgc ccggcgagtt acgcgtttct gtagtcagtg cctttattgg cgcaccggtg
    15361 ctgatcttcc tcgtgcgacg taaaacgcga ggtggcgcat gatttacgtc tctcgccgat
    15421 taatcatcac ctgtttgctg ctaattaccg cctgtgtggt tgcaggtatc tggggattac
    15481 gcagcggtac cgtcacgctg gaaacctcgc aggtattcgc cgcgctgatg ggcgatgcgc
    15541 cgcgcagtat gacgatggtg gtcactgaat ggcgtttacc acgcgtgctg atggcgctgt
    15601 taattggcgc ggctctgggc gtcagcggcg cgatttttca gtcgctgatg cgtaacccgc
    15661 tcggtagccc tgacgtaatg ggctttaaca ccggggcgtg gagcggcgtg ctggtggcga
    15721 tggtgctgtt tggtcaggat ctgacggcta tcgcgctggc agcaatggtg ggcggcattg
    15781 tcacttcgct gctggtctgg ctgctcgcct ggcgtaacgg catcgacacc tttcggttga
    15841 ttattattgg tatcggcgtt cgcgccatgc tggtggcctt taatacctgg ctgttgctga
    15901 aagcgtcttt agaaacggcg ctaacagcgg gtttatggaa tgccggatcg ctcaacggcc
    15961 tgacgtgggc aaaaacctcg ccttccgcac ccatcattat attgatgcta attgccgccg
    16021 ccttactggt acgccggatg cgcttgctgg aaatgggcga tgataccgcg tgtgcgctgg
    16081 gcgtcagcgt cgaacgttcg cgtctgttaa tgatgctggt tgcagtggtg cttaccgctg
    16141 cggcaacagc gcttgccggg ccgatttcct ttattgcttt agtcgcgccg cacattgccc
    16201 gacgcattag cggcaccgct cgctgggggc tgacccaggc ggcgctgtgc ggggcgttgt
    16261 tactgctggc ggccgatctc tgcgcccaac aactgtttat gccgtatcaa cttccggttg
    16321 gcgtcgttac cgtcagcctc ggcggtattt accttatcgt cttgttaatt caggagtctc
    16381 gcaaaaaatg accgaatcag tagcccgttt gcgcggcgaa cagttaaccc tcggatatgg
    16441 caaatatacc gttgcggaga atctgactgt agaaatacct gatggtcact tcacggcaat
    16501 tatcgggcca aatggctgcg gtaaatccac gttactgcgt actttaagcc gcctgatgac
    16561 acctgctcac gggcatgtct ggctggatgg tgagcacatt caacattacg ccagtaaaga
    16621 ggttgcacgc cggattggtc tgttggcgca aaatgctacc acgccgggcg atatcaccgt
    16681 gcaggagctg gtggcgcgtg gacgttaccc gcatcaaccg ctgtttaccc gctggcgcaa
    16741 agaggatgaa gacgcggtaa cgaaagcgat gcaggccacg ggaatcactc atctggcaga
    16801 tcaaagcgtg gatacccttt ctggcggaca acgccagcga gcgtggatag caatggtgct
    16861 ggcccaggaa acggcaatta tgctgctcga tgaacccacg acctggctgg atatcagtca
    16921 tcagattgat ttgctggaac tgttaagcga actgaaccgc gagaaaggct ataccctggc
    16981 ggcggtgctg cacgatctta atcaggcctg tcgttacgcc agccatttga ttgcattgcg
    17041 ggaagggaaa attgttgctc agggagcgcc gaaggagatt gtcactgctg aattgatcga
    17101 gcgcatttat ggtctgcgct gcatgattat tgacgatccg gtagccggaa ctccgctcgt
    17161 ggtgccgctc ggacgaacgg caccttcaac tgccaagatt taaactaagt gctcttccat
    17221 cacggcatcc tgttttctgg atgccatcgc atggcgcaac agcacgccac cacaagccac
    17281 catcccgccg atcatcgcag aaaggatcac aataatcgcc ttacccggac cgtctttttt
    17341 cactggcaat gacgggctta actgatattt aaacggcgta aaattcacat cgttgatatt
    17401 tgcttttgtt agctgctcaa caagatactg acgattacgt aattcaccgt tcaattccgc
    17461 aacgtcagta accgcttttt caatttccag tttgcgttca ataccgtctg cgccgagaga
    17521 aatagagaaa tcggggtcat ctttaacggc ctgaccatta ctgtaaacgg gctttttaat
    17581 tcctgccgcg ttggcaatgt cgagtgaata attgaggcgc tgaatgtttg catcaagttg
    17641 atttttcgtt ttaatgcgat cctgagccag tttttctttt tcaaactggg ttttgatctc
    17701 cagtttatta cggacgtttt ctatcgactc tttcaccacc aacgcagaga tataatcgat
    17761 atacccgctc aaaacggtct gcgcctcttc actggttggc gcggtaaaac ttagcgtcca
    17821 ggaggtatac agtgacggtt catctttttt cttactggca ttgtcatcaa ccgctttcat
    17881 tttttcgctc aatgcgacga tagctcgatg caaatccagt tcgtcgattt tcgcctcttt
    17941 taattggtcc atcacataag gtgatgagcg caggtactct tctagtaagc taacagactg
    18001 aaacttcttg ataaacaggt taaatacttc tgtacgatca attttgatat ccagatccag
    18061 cacacgaagc ttagtgaatg ttttctccag ttcttgccac tgaacaggtt ctggaggcgt
    18121 gacaaccgcc gcgctggtcc atttttgcgg caggatgaaa gagatcagca atcctgtgca
    18181 ggcaaacgca aaaacgaccg ccatgaccgt tttttttgcc cgccataaaa cgtcgattag
    18241 attaagtaaa tcaatttcat tattactggg cgacgccaga ggatactcgg gaaaatgagc
    18301 gtcacttccc tgtttaatat tcagtgatga catgcggtat aacctgaaat gggtccaata
    18361 agagtaaatc tccacggccc ccactttacc agttggtgag atttatccga agctgaagtt
    18421 tgtaaattcc tcccactgaa tgcaacattc actctatttc agagaaatat ccgttaaatt
    18481 gataaattaa ataaataata aacccataat catttattgt aattatgggt ttatagataa
    18541 tataaattta cttatttagc gtcgcacgaa taatcggccc tattttttca aacgccatcg
    18601 gcgagataat atccacatgc gcacaatcct gacgatagat atccagctcc gtaatccacg
    18661 gcgaccaggc gcgttcggga ttcatacctt cctgaagcgt gcgttcagca acaaacagcg
    18721 tcgctttacc ttcaaacggt acgctatgag cagtcgtcag caggcgcaca gcatcagcgt
    18781 agttgccttc aatggtggta aacaactccg ttgaagtact tccctgctgt gccgccagga
    18841 aggcctcgcg ctcgcggtta atctccgcca gcacttccgg gtccaggcca ttagcctctt
    18901 tttcctgcca gttttgcgtt tctggcggcc aggtatccag caagccaaga aatgccacct
    18961 gttcgccacg ggcacgcagc cgcgccgcaa taccctgcgc cagcgtaccg cccagcgaat
    19021 aacccagcag gtaataaggg ccgtgcggtt gatgctcaag taacgttgcc agatgcgctt
    19081 cgcagacttc atccaggttt gccgccgtct gcatggggcc atgagggcgt ggcgactgga
    19141 tgccaataat cgaccattgt ggatcgagat aacgcgagag cacgctaaac tgccaggcaa
    19201 aaccggatgc cggatggaaa caaaacagcg tcggaccatt accttcacgc aacggcagaa
    19261 tggtttcgaa tcccatgcgc tgggtgctgt cttcttcacc atcaataatc gttgccagtt
    19321 tggcgacggt tgacgcgacc atcacctgac ccggcgtcac ctgacgggca aactgccgac
    19381 ttaactgcgc tgccagtttc attgccagta gcgaatgacc gccaagcgca aagaaatcag
    19441 catcggcatc ctgcacgtca caacccagca acgacgagaa tgccgcggcg ataatcgttt
    19501 cactgcccgc tttcggcgca cgccccggcg cttgtgcctt cagttcaggc aacggtaagg
    19561 ctttgcgatc cagcttgccg ttggcgctaa gtggtaactg tggaagttgc agcagaacca
    19621 ccggtaccat atgtggtggc aatgtttcac gaagctgcgc ctgtaatgcg ctggtatcca
    19681 acggcagacc tgattgcgac accagatagc ccaccaactg acgcgcatca ccaccagtgg
    19741 ctgccgcctg gttaatcaca caggcgtggg taacggcttg ttcgacatcc ggcagcgcct
    19801 gcatcacgcg atcaatttcg cccagttcga tacgctgccc gcgaattttt agctgatcat
    19861 cactacgccc gagatactcc accgcgccgt tatccagcca gcgggcaaca tctccggtac
    19921 ggtacatgcg ttcacctggc gcaaaaggat cggcaataaa gcggctggct gtcagatcgg
    19981 gtcgtccaag atacccctgc gccagttgaa taccggtgag atagagatct cccgccacac
    20041 ccggcggcac cggatgcatc atcgcatcga gaatgcgcag gcccgtattc cacaccggat
    20101 aaccaatcgg cacactgctg ccgcgtacct gtgccagttc ctcgccaaag gccggatacc
    20161 agctgacatc taccgctgct tccgtcgggc catacagatt atgcaacggc gcgccggtta
    20221 actgttgcca ttcgcggcat aaatcagccg gtaaggcctc accactacag aaaacctgtt
    20281 tcaacgtcgc gcaactctga cgagcggttt gcggcgtcat cgatgcaaca aatgccgcca
    20341 gcatcgacgg cacaaagtgc gtggttgtta caccatattc ggcaaagaat tgctgcatag
    20401 cgagcgggtc gcggtgcgct tccggttcag ccatcaccag tttagccccg gcaataaacg
    20461 gccagaaaaa ctcccacacc gagacatcaa aactgcacgg cgttttttgg gcaacgacat
    20521 cttcgcctgt aagcgggtag tggttttgca tccagagcag gcggttaacg atagccgtct
    20581 gcccgaccat tacccctttc ggcctgccgg tggaaccgga ggtgaagatg atataagccg
    20641 tgtggtgcgg ttgtgaaagc tgcagcggcg cactgccctg tggtataagc ggggcgttat
    20701 agcaaaggcg ggttaaatct ggaacatcgg caaagcgcgg cagttgatcg tcggtggtga
    20761 ttaacagcga tggacgcgca tcttccagca tcattttcag gcgatcgtcc ggatagccgg
    20821 tatccagagg tagccaggcc gcaccagctt caacaatcgc atgtagcgcc agggtcaaaa
    20881 agaccgagcg cggtaatgcc accgccacgc tgtcgcctgg tttaacgccg cgctcacgca
    20941 gcagattcgc cagcgccacc acctgttcgc gcatttcccg atagctgaac tggtaacgcg
    21001 catcaaccag cgccggagca tccggtgttt ttgccgcttg ttctgccacc agcgcgctca
    21061 gcgtggtttc tggaatctca acctgagtgg cgttgatctg cgccagctgc gcatattcac
    21121 ctggcagcat aatatcgaca tcgccgcaca acagcgccgg atccgcggcg aactgggcaa
    21181 tcagcatttt caggcgttca gcgtgttgaa ttaacgttgg ctcatcgtaa cgctgtttat
    21241 tggcgaggat ctcaatactc aaatcaccgt gttcatccgg gaacagggcc agctcaaggt
    21301 cattaaccgg accggtagcc agggtatggg tttgcgcctg aacatcagga atatccagtt
    21361 ggtaatcaaa taccttgata ttgagtaccg gaccaaacag cggttcatca cctgccgctc
    21421 gcccgctgtc acggacaatt tgttcggcat cgtaacgttg atggcgacgc atttttttca
    21481 gttgagccgc cagtcgggtt gccagttccg gcagcgtttc ttgcgccgca atatgaatac
    21541 ccaacggcaa aacgttgagc acgggtccgg tagccgtcag cgccgccgag cccagtcgac
    21601 gcataaagat aaatccggca gcgtagtcca tgcggttgca caatcgcccc agccacaagg
    21661 ctgccaacgc aagggctaaa tcggtacgct gcacacctga aagttgcgta gccaactggc
    21721 ggaattcccc gtcggtaaat tccagtttca ggcgcagaat atctgccgag gcgctgcgcc
    21781 ccggtaaagg tgccggagaa agtgacgcgg gcggcggcaa ttgacgacgc tgttccgccc
    21841 agaatgccgc atcacgctgc caggcttcgc tttcgcggta ttgctggtac tcttccacta
    21901 catcagcgaa aggcgtaaac ggcgaagcag gcgtaggttc gccacgcagc catgcgcagt
    21961 aaatgttggc gatctggcgg gtaatggccg ggaaactaaa cccatcgacc agcaaatggt
    22021 gataacgctg ataccagtac cagcggttat ccgccacctg tatcaactga tgaaagacca
    22081 gtggtttacc gctatcgacg cgcagatctt gttgcaaatc cgcctgcatt aatgcctgcg
    22141 cagtaccgtg cggatcaatg ttggttcgca ggtcgataat ttctggcagt tcgaacgtca
    22201 gcgcatcatc gacccattgc cagacttcgc cgttatcttc cgtaaaacgc atccgcagcg
    22261 tatctgcttg cgctaatccg gcaaccaccg cgcgggccag taatggcgca tcaacctctc
    22321 cggttaactc aacgtaatgc gccacgctcc aggcggaggg taaatccgac agtttttctg
    22381 ccatccagat gccgggctgt gcggcgacca aaggtaaatg ctggctcatt gtgcctcctg
    22441 caactgggtg aaattcgccg gtgtcagagt acgccagtgg acttccagcc actgctggca
    22501 ggactcttgt gactgcggct gacacacaat gtcccagcct gccggtaaga ggcattgttg
    22561 cggccacaga ctgaattgcc cctgcgcatt gcgcaaaatg taaaacgctc cctgtggatc
    22621 atcgaaggga ttactgaatg ccatattcaa ctcctgtcat ggaaaagtgg ttgccagagg
    22681 tcgattagcc cctgcatcaa gccaccgcgc caacaaagcg catcatgtcc gccgtcaacc
    22741 tgacgccaga aaatggattc ttttatgggg tgtaattgcg catacagcgc ctgattggcc
    22801 tgcatgatca tcggctcgcg aatacccgct tccagcacaa tgcgcagacc ttcggcgcta
    22861 acttgaccag ctttaagttg ctcaagtaaa gcaccttctt gctgcccgcc ccgatgcggc
    22921 caccagtacg atcctgactg gcttaataca cagccaaagc gttcaggcca gtgcagtccg
    22981 gcatacagcg cggaaagccc accaaaactc tgcccggcga ccacggtgcg atcggcgcga
    23041 tcgctaaaag aggcaatagc tttcaccagg ggtaataact cttgctgtac tgccagccag
    23101 aaatccgcat tacacggcag ttcgtgggcg cggtgcgtgg tgtcgatagc atcgatcaac
    23161 acatacacgg cgggaggaag ttgccgacga tgggtcagcg aagttagcgc aggccagacg
    23221 ggcatactct gcgcccaaaa ttcaccatca agcaaaactg ccagcgggcg ttcttctgct
    23281 gttgcatcgc cggtgataaa aatccataca cggcgtgaat ttttcaaccg ttcacttttc
    23341 cagataattt ctttggcagg cgtttctggc gcttgcggac aatcccatcc cggttgcaga
    23401 ggcgcttgcg gcatttcgag tgcagaaaca gcgtgccctc gcccgccttt ccagctttgt
    23461 ggattcagcg gatcggctat cgcctggggt aatagttttc gccagccttc acgtaattcg
    23521 aggcgatcgg gggatggtgc agaaaaaatg tcatcgcgtt cggtgggaat aaagcagtag
    23581 ctgccgcgcc agttggcatt gagctgtgtc gtccactgcc agacgttggt gcctgcaatt
    23641 cgctgcatcg actggggctg gctgttctga tggtgatcgg tcacaccagt gatgtagacc
    23701 catacgcgct ttatcgtcga gtattcttca gaaccttggg gatcacgcca ccagaaagtg
    23761 acctcaaaca tttcgtcatt cagacgctgc cattccgggc catgtttcga ctgccaccag
    23821 ctctcacttc ctacttttaa cgccgtcaca ccataacccc atgtttactg tgcaattttt
    23881 cattgattgc agaaatatat tgataatatt attgataact atttgcattt gcaatagcgt
    23941 aatggcgcgc cgtgggaagc gcggacatta attaaccaac tgcactgcgt gtctttcagg
    24001 atcaaaggtt ttcgcggtag cggggtgcgt cgtattgatg acgaccatgc ccgacagttg
    24061 caattcgtgg caaaaatgca ggaataaaac aatgaacaag aagattcatt ccctggcctt
    24121 gttggtcaat ctggggattt atggggtagc acaggcacaa gagccgaccg atactcctgt
    24181 ttcacatgac gataccattg tcgttaccgc cgccgagcag aacttgcagg cgcctggcgt
    24241 ttcgaccatc accgcagatg aaatccgcaa aaaccccgtt gcccgtgatg tgtcggagat
    24301 catccgtacc atgccaggcg ttaacctgac cggtaactcc accagtggtc agcgtgggaa
    24361 taaccgccag attgatattc gcggcatggg tccggaaaac acgctgattt tgattgacgg
    24421 caagccggta agcagccgta actcagtgcg tcagggctgg cgtggcgagc gcgatacccg
    24481 tggtgatacc tcctgggtgc cacctgaaat gattgaacgt attgaagttc tgcgtggtcc
    24541 ggcagctgcg cgttatggca acggcgcggc gggcggcgtg gttaacatca ttaccaaaaa
    24601 aggcagcggt gagtggcacg gctcctggga tgcttatttc aatgcgccag aacataaaga
    24661 ggaaggtgcc accaaacgca ccaacttcag cctgaccggt ccgctgggcg acgaattcag
    24721 cttccgcttg tatggcaacc tcgacaaaac ccaggctgac gcgtgggata tcaaccaggg
    24781 ccatcagtcc gcgcgtgccg gaacgtatgc cacgacgtta ccagccgggc gcgaaggggt
    24841 aattaacaaa gatattaatg gcgtagtgcg ctgggacttc gcgcctctgc aatcactcga
    24901 actggaagcg ggctacagcc gccagggtaa cctgtatgcg ggtgatactc agaacaccaa
    24961 ctctgacgct tacactcgct cgaaatatgg cgatgaaacc aaccgcctgt atcgccagaa
    25021 ctactcgctg acctggaacg gtggctggga taacggcgtg accaccagca actgggtgca
    25081 gtacgaacac acccgtaact cgcgtattcc ggaaggtctg gcgggcggta ccgaagggaa
    25141 atttaacgaa aaagcgacac aggatttcgt cgatatcgat ctcgatgacg tgatgctgca
    25201 cagcgaagtt aacctgccga ttgatttcct cgttaaccag acgctgacgc tgggtacgga
    25261 gtggaatcag cagcggatga aggatttaag ttccaacacc caggcgctca ctgggacgaa
    25321 tactggcggt gctattgatg gtgtgagtgc caccgaccgt agcccgtatt caaaagcaga
    25381 aattttctcg ctatttgccg aaaacaatat ggagctgact gacagcacca tcgtaacgcc
    25441 ggggctgcgt ttcgatcatc acagcattgt tggcaataac tggagcccgg cgctgaacat
    25501 atcgcaaggt ttaggcgatg acttcacgct gaaaatgggc attgcccgcg cctataaagc
    25561 accgagcctg taccagacta acccgaacta cattctctac agtaaaggtc agggttgcta
    25621 tgccagcgcg ggcggctgct atctgcaagg taatgatgac ctgaaagcgg aaaccagcat
    25681 caacaaagag attggtctgg agttcaaacg cgacggctgg ctggcgggcg tcacctggtt
    25741 ccgtaacgat tatcgcaata agattgaagc gggctatgtg gctgtagggc aaaacgcagt
    25801 cggcaccgat ctctatcagt gggataacgt accgaaagcg gtggttgaag gtctggaagg
    25861 atcgttaaac gtaccggtta gcgaaacggt gatgtggacc aataacatca cttatatgct
    25921 gaagagtgaa aacaaaacca cgggcgaccg tttgtcgatc atcccggagt atacgttgaa
    25981 ctcaacgctg agctggcagg cacgggaaga tttgtcgatg caaacaacct tcacctggta
    26041 cggcaagcag cagccgaaga agtacaacta taaaggtcag ccagcggttg gaccggaaac
    26101 caaagaaatc agcccgtaca gcattgttgg cctgagcgcg acctgggatg tgacgaagaa
    26161 tgtcagtctg accggcggcg tggacaacct gttcgacaaa cgtttgtggc gtgcgggtaa
    26221 tgcccagacc acgggcgatc tggcaggagc caactatatc gcaggtgccg gggcgtatac
    26281 ctataacgag ccgggacgta cgtggtatat gagcgtaaac actcacttct gatgctaacg
    26341 tcagattgtt gacaaagtgc gcgtcgttca tgccggatgc ggcgtgaacg ccttatccgg
    26401 cctacaaaaa tcttgccaat tcaatatatt gcaggaccac gtaggcctga taagcgtagc
    26461 gcatcaggca gttttgcgtt tgtcatcagt ctctaatatg gtcgacatga aaactacgca
    26521 taccgccctc ccctttgtag gacatacgct gcattttgtt gagtttgatc cggcgagttt
    26581 ttgtgagcag gatttactct ggctgccaca ctacgcgcaa ctgcaacacg ctggacgtaa
    26641 acgtaaaaca gagcatttag ccggacggat cgctgcagtt tatgcgctgc gggaatatgg
    26701 ctataaatgt gtgcccgcaa tcggcgagct acgccaacct gtgtggcctg cgggggtata
    26761 cggcagcatt agtcactgtg ggactacggc attagccgtg gtatctcgtc aaccgattgg
    26821 cattgatatc gaagagattt tctctgtaca aaccgcaaga gaattgacag acaacattat
    26881 tacaccagca gaacacgagc gactcgcaga atgcggttta accttttctc tggcgctgac
    26941 actggcattt tccgccaaag aaagcgcatt taaggcaagc aagatacagg ccgctcaagg
    27001 ttttctggat tatcagataa ttagctggaa taaacagcag atcatcattc gactagagga
    27061 tgagcagttt gctgtgcact ggcagataaa agaaaaaata gtcataacgc tgtgccaaca
    27121 cgattaattg acaacatctg gtacgattcg cccgcagcca tcactgacca cgggcgaaag
    27181 tgtaaagcag gtgccttacc atcctgacct gacaaccgga tatgcgggga ttgctcccat
    27241 aagcgctaac ttaagggttg tggtattacg cctgatatga tttaacgtgc cgatgaatta
    27301 ctctcacgat aactggtcag caattctggc ccatattggt aagcccgaag aactggatac
    27361 ttcggcacgt aatgccgggg ctctaacccg ccgccgcgaa attcgtgatg ctgcaactct
    27421 gctacgtctg gggctggctt acggccccgg ggggatgtca ttacgtgaag tcactgcatg
    27481 ggctcagctc catgacgttg caacattatc tgacgtggct ctcctgaagc ggctgcggaa
    27541 tgccgccgac tggtttggca tacttgccgc acaaacactt gctgtacgcg ccgcagttac
    27601 gggttgtaca agcggaaaga gattgcgtct tgtcgatgga acagcaatca gtgcgcccgg
    27661 gggcggcagc gctgaatggc gactacatat gggatatgat cctcatacct gtcagttcac
    27721 tgattttgag ctaaccgaca gcagagacgc tgaacggctg gaccgatttg cgcaaacggc
    27781 agacgagata cgcattgctg accggggatt cggttcgcgt cccgaatgta tccgctcact
    27841 tgcttttgga gaagctgatt atatcgtccg ggttcactgg cgaggattgc gctggttaac
    27901 tgcagaagga atgcgctttg acatgatggg ttttctgcgc gggctggatt gcggtaagaa
    27961 cggtgaaacc actgtaatga taggcaattc aggtaataaa aaagccggag ctccctttcc
    28021 ggcacgtctc attgccgtat cacttcctcc cgaaaaagca ttaatcagta aaacccgact
    28081 gctcagcgag aatcgtcgaa aaggacgagt agttcaggcg gaaacgctgg aagcagcggg
    28141 ccatgtgcta ttgctaacat cattaccgga agatgaatat tcagcagagc aagtggctga
    28201 ttgttaccgt ctgcgatggc aaattgaact ggcttttaag cggctcaaaa gtttgctgca
    28261 cctggatgct ttgcgtgcaa aggaacctga actcgcgaaa gcgtggatat ttgctaatct
    28321 actcgccgca tttttaattg acgacataat ccagccatcg ctggatttcc cccccagaag
    28381 tgccggatcc gaaaagaaga actaactcgt tgtggagaat aacaaaaatg gtcatctgga
    28441 gcttacaggt ggccattcgt gggacagtat ccctgacagc ctacaaaacg caattgaaga
    28501 acgcgaggca tcgtcttaac gaggcaccga ggcgtcgcat tcttcagatg gttcaaccct
    28561 taagttagcg cttatgggat tgctccccgc acaacggcta cttcttcggt tcgtaagcga
    28621 gaacagcctt aaactcaata ttacgttcct tcaccgtaaa ctcacacagc gagtcgccga
    28681 ccagaagcgt aaatcccagc accgttaaac acagcactat gactgccaca agggcatatt
    28741 tcgtcagcat gtttatattg cctccatgcg aagaagggac taccatccaa attgttcggg
    28801 tttggagtgg cagccccagg gttgatagaa atatcgtcct ggggcttcat ctttccagac
    28861 ctcagagtta acctgaaacc ggaaagcttc aggcacccgc cgttatctta cgcttcctca
    28921 gcaaaatagc tgtttattta tacagtgaat cctgtttcgg acttctcact ccccatttga
    28981 tcaactgaag ctgagcccgt tttttctgca tgcctcaatc gtcaaaattc ttcgccacca
    29041 gccagctgtg ccataacttg ccacattgaa aaagtagcta aattgcttca ctcacaatca
    29101 gttcaccatc accaaaaaaa gaaatattcc agaacttccg catctcgccc agtcgctccc
    29161 acttctatac tgaatagaaa acgccaacat aagagaaacc tatgccatta cccgattttc
    29221 atgtttctga accttttacc ctcggtattg aactggaaat gcaggtggtt aatccgccgg
    29281 gctatgactt aagccaggac tcttcaatgc tgattgacgc agttaaaaat aagatcacgg
    29341 ccggagaggt aaagcacgat atcaccgaaa gtatgctgga gctggcgacg gatgtttgcc
    29401 gtgatatcaa ccaggctgcc gggcaatttt cagcgatgca gaaagtcgta ttgcaggcag
    29461 ccgcagatca tcatctggaa atttgcggcg gtggcacgca cccgtttcag aaatggcagc
    29521 gtcaggaggt atgcgataac gaacgctatc aacgaacgct ggaaaacttt ggttatctca
    29581 ttcaacaggc gaccgttttt ggtcagcatg tccatgttgg ttgcgccagt ggcgatgatg
    29641 ccatttattt gctgcacggc ctgtcacggt ttgtgccgca ctttatcgcc ctttccgccg
    29701 cgtcgccata tatgcaagga acggatacgc gttttgcctc ctcacgaccg aatatttttt
    29761 ccgcctttcc cgataatggc ccgatgccgt gggtcagtaa ctggcaacaa tttgaagccc
    29821 tgtttcgctg cctgagttac accacgatga tcgacagcat taaagatctg cactgggata
    29881 ttcgccccag tcctcatttt ggcacggtgg aggttcgggt aatggatacc ccgttaaccc
    29941 ttagccatgc ggtaaatatg gcaggattga ttcaggctac cgcccactgg ttactgacgg
    30001 aacgcccgtt taaaaatcag gagaaagatt accttcttta taaattcaac cgtttccagg
    30061 cctgccgcta tgggctggaa ggcgtcatta ccgatccgca cactggcgat cgtcgaccgc
    30121 taacggaaga caccttgcga ttgctggaaa aaatcgcccc ttctgcaaat aaaattggcg
    30181 catcgagcgc aattgaagca ctgcatcgcc aggtcgtcag cggtctgaat gaagcgcagc
    30241 tgatgcgcga tttcgtcgcc gatggcggct cgctgattgg gctggtgaaa aagcattgtg
    30301 agatctgggc cggtgactaa gccgggaatt gccttacaga agaatatccc tgacaatggt
    30361 gttttaactt acatttaaca atgttatgaa acacccttta gaaaccttga ccaccgcagc
    30421 aggcattttg ctgatggctt tcctctcttg cctgctgctt cccgcccccg cattggggct
    30481 gacgctggca caaaaactgg tgaccacgtt ccatctgatg gatcttagcc agctttacac
    30541 tttattgttt tgtctgtggt ttttagtgct gggcgctatt gagtattttg ttctgcgctt
    30601 tatctggcga cgctggttct cgctggcgga ttaaacgtcg attatcgccg aacttcgcgg
    30661 catactttgc ttattctcct tcgcctaaag gaacgtttat ggataagcaa tcactgcacg
    30721 aaacggcgaa acgcctggct cttgagttac cctttgtcga gctttgctgg ccttttggcc
    30781 cggagttcga tgtttttaaa attggcggca agatttttat gctgtcgtcg gagctgcgcg
    30841 gcgtcccctt tatcaatctg aagtccgatc cacaaaaatc cctgctaaat cagcaaatat
    30901 acccaagcat caagccaggg tatcacatga ataaaaagca ctggatttcg gtgtatcccg
    30961 gcgaggaaat ctccgaagcg ttacttcgcg atctgatcaa cgattcgtgg aatctggtgg
    31021 ttgatggtct ggctaaacgc gatcaaaaaa gagtgcgtcc tgactcaacc gtaaatcaat
    31081 agcgcatttt tctcgcttac catttcatct cgatccttgt aatctgctgg cacgcaaaat
    31141 tactttcaca tggagtcttt atggatatca tttctgtcgc cttaaagcgt cattccacta
    31201 aggcatttga tgccagcaaa aaacttaccc cggaacaggc cgagcagata aaaacgctac
    31261 tgcaatacag cccatccagc accaactccc agccgtggca ttttattgtt gccagcacgg
    31321 aagaaggtaa agcgcgtgtt gccaaatccg ctgccggtaa ttacgtgttc aacgagcgta
    31381 aaatgcttga tgcctcgcac gtcgtggtgt tctgtgcaaa aaccgcgatg gacgatgcct
    31441 ggctgaagct ggttgttgac caggaagatg ccgatggccg ctttgccacg ccggaagcga
    31501 aagccgcgaa cgataaaggt cgcaagttct tcgccgatat gcaccgtaaa gatctgcatg
    31561 atgatgcaga gtggatggca aaacaggttt atctcaacgt cggcaacttc ctgctcggcg
    31621 tggcggcgct gggtctggac gcggtaccca tcgaaggttt tgacgccgca atcctcgatg
    31681 cagaatttgg tctgaaagag aaaggctaca ccagtctggt agttgttccg gtgggtcatc
    31741 acagcgttga agattttaac gctacgctgc cgaaatctcg tctgccgcaa aacatcacct
    31801 taaccgaagt gtaattctct cttgccgggc atctgcccgg ctatttcccc tcagattctc
    31861 ctgatttgca taaccctgtt tcagccgtca tcatagtctg ctgttgtata aaggagacgt
    31921 tatgcaggat ttaatatccc aggttgaaga tttagcgggt attgagatcg atcacaccac
    31981 ctcaatggtg atgattttcg gtattatttt tctgaccgcc gtcgtggtgc atattttttt
    32041 gcattgggtg gtactgcgga ccttcgaaaa acgtgccatc gccagttcac ggctatggtt
    32101 gcaaatcatt acccagaata aactcttcca ccgtttagct tttaccctgc aggggattat
    32161 cgtcaatatt caggcggtat tctggctgca aaaaggcacc gaagcggcag atattctgac
    32221 tacctgcgcg cagttgtgga tcatgatgta tgcgctgctt tcagtcttct cgttgctgga
    32281 tgttattttg aatctggcgc agaaattccc ggcggcatct cagttaccgc tgaaagggat
    32341 atttcagggg attaaactga tcggcgcgat tctggtcggc attttgatga tctcgctgtt
    32401 gattggtcag tcgccagcga ttctgatcag cggtcttggt gcaatggctg ccgtgctgat
    32461 gttggtattt aaagatccga ttcttggtct ggtggcaggt attcagcttt ccgcgaacga
    32521 tatgttgaaa ctgggcgact ggctggagat gccgaaatac ggcgcggatg gcgcggtgat
    32581 cgatattggg ttaaccaccg tcaaagtgcg taactgggac aataccatta ccactattcc
    32641 cacctggtct ctggtctctg actcctttaa aaactggagc gggatgtcag catctggcgg
    32701 gcgacgtatt aagcgcagta tcagtattga tgtcaccagt attcgttttc ttgatgaaga
    32761 cgaaatgcaa cgtctgaata aagcgcattt gttaaaacct tatttaacca gccgccacaa
    32821 ggaaattaat gagtggaatc gccagcaagg ttctacggag tcggtattaa acctgcgccg
    32881 aatgaccaat attggaacct ttcgtgccta tctgaacgaa tatctacgta accatccgcg
    32941 gattcgtaaa gatatgacct taatggtacg ccaactggct cctggcgata acggtttacc
    33001 gctcgagatc tatgcgttta ccaacaccgt ggtgtggctg gaatatgaaa gcattcaggc
    33061 tgatatattc gaccacatat ttgcgattgt cgaagagttt ggtctgcgac ttcatcagtc
    33121 gccaaccggc aatgatattc gctctctggc gggtgcattt aagcagtaat taaaaaaacc
    33181 gctctcatcg aatggatgag agcggacatc gttttgtcgg atgtagcgtg aatgccttat
    33241 ttccgacgca gcgttttaaa tgctacaaac aggaatacaa tccacaccgg cagcagaatc
    33301 gctgacaagc gcatatcatc catcgtgcac atcagcagca aaatcatgcc gaggaaggca
    33361 atgcagagat agttgccgaa cggataaagc agcgccttaa actgtgtttc acgtccctga
    33421 cgtcgcatcg cagcacgaaa acgaagatgc gccaggcaga tcataatcca gttcaacagc
    33481 agcgttgcta ccaccagcgc catcagcaga ccaaacgctt tttgcggcag cagatagttg
    33541 attaacacca ccagcgaagt gatcgctccg gaaagcatca gcgagttaat cggcacaccg
    33601 cgacggctga cgcgagtcaa aaacttcggc gcattaccct gcacagaaag gccaaacagc
    33661 atgcggctgt tagagtaaac cccgctgtta tacaccgata atgatgctac cagaatgacg
    33721 aagttcagcg cagaggctac cacgttgctg tcgagattat ggaaaatcat cacaaacggg
    33781 ctactgttgg atttcacttc cacccacgga tagagtgcca gtaaaaccac cagtgaaccg
    33841 atataaaaca gcaggatgcg atacaccacc tgattcactg ctttcgggat gcttttttcc
    33901 ggagcgcgcg cttcagcggc agtaatccca atcagctcca gcccgccgaa ggagaacata
    33961 atcaccgcca gcgacaaaat cagcccattc cagccggtgg caaaaaaacc accgtagcgc
    34021 cagaggttat cgatactggc tttctcgccg ccgtgcccag aaaacagcag ccacaggcca
    34081 aagccgatca taccgatgat cgccagcact ttaatcagcg caaaccagaa ctcggtttcg
    34141 ccatataagc gcacgttcac caggttaacg gcgttgatga taataaagaa ggcggcagcc
    34201 caaatccacg ttggaacatc cgggaaccag tactgcatat agatgcccgc agcggtcagc
    34261 tctgccattc ccaccagcac gaacattacc cagtagttcc agccagagag gaagcccgca
    34321 aacggtcccc agtatttata ggcaaagtgg gcaaatgaac cggataccgg ctcctcaacc
    34381 accatttcgc caagctggcg cataatcagg aaagcgatga tcccggcgac gccgtagccc
    34441 agcaatacag ccggacccgc catctgaatc gccgggccaa tgccaagaaa cagaccagta
    34501 ccaattgcgc cacccagcgc aatcagttga atatgacggt tatgtaatcc gcgatgaagc
    34561 gtcggctctt gattcgacgc agtatcttcc gatacggttg acgcgttttt cacgcctttc
    34621 ccctgtgtgt cttttttgtt gaggggcacc ttttaacatt tagtgcccat cgtcgcaaga
    34681 cacaatccac acggttaaac ggggtatcct gcttttattt ccgtacccga tgtcggtgca
    34741 gccacatcag cttatacgcc gccgggataa taaacagcga tagcaaaggc gcggtgatca
    34801 tgccgccaat catcggcgcg gcaatccggc tcatcacctc tgaacctgct cccgttcccc
    34861 acagaatcgg cagcagacca gcgataatca ccgccaccgt catcgctttc gggcgcacgc
    34921 gcaggaccgc gccgtgatac aacgcctcat ccagcttctg ctcgctgaat gtttgcggat
    34981 tattcaacga cggctcggcc tctatggcgt gacgtaaata catcagcatc accacgccaa
    35041 attcggcggc gaccccggca agggcaataa aaccggtgcc cgtcgccacg gaaagatgaa
    35101 agcccatcca ccacagcaac cagatgccgc ccaccagcgc aaacggtacg ctgctgataa
    35161 tcagcaacgc ttcgcccacc cgacggaacg ccaggtacaa cagcacgaag atgatcatca
    35221 gcgtcatcgg caccatcagt ttcagcttat ggttggcgcg ctccagtagc tcgaactgcc
    35281 cggagaatgc cacgctggtg cccggtttta actgcacttt ttcagctatc gctttttgca
    35341 gatcgtgaac caccgacacc atgtcacgat cgcgggcatc gatataaatc cagctcgtcg
    35401 ggcgcgcatt ctcggttttc agcatcgacg gtccggtaga gactttaacg tcggccacgt
    35461 ctgccagggt gatttgctgc ttcatcggcg tgaggatcgg caactggcgc agtgcctgcg
    35521 ggctatcgcg ccagctttgc ggataacgca gattaattgg ataacgggca atcccttcca
    35581 ccgtttcgcc aaccatcgcc ccgcccaccg cagatttcac aaacaattgc acatccgcca
    35641 ccgtcatacc gtaacgcgcg gctttttcac ggttaatctc aacgttgata tagcgcccac
    35701 cttccagccg ctcggcaaga gcagaagcta cgcctggcac cgttcgcgcc acttcttcaa
    35761 tttgctccgc catcgtgtcg atatccgcca gcacagtgcc ggaaacttta atgccgatag
    35821 ggcttttaat gccagtcgag agcatatcga tacggttacg aattggcggc acccacagat
    35881 tcgccagccc cggcagacgc acggtgttat ccagttcctc aatgattttg tccatcgtca
    35941 tgcctggccg ccactgatct tgtggcttaa gctggatagt cgtttctacc atctccagtg
    36001 gagctgaatc ggtggcggtt tccgctttcc cggttttgcc aaatacccgc gccacttccg
    36061 gtacgctcat aatcagcttg tcggtttttt gcagcatgct cgccgcctct gctgcggaaa
    36121 tccccggcag cgtcgatggc atatacaaca agtcgccttc attgatctgc ggtaaaaatt
    36181 ccccgccaac tttattgagc ggccagagta ccgtcagcac cgaaagcgct gccaccaaca
    36241 gcgtggtttt cggccagtgc agtactttca gcaacagcgg atgataaaca cgaatcaaaa
    36301 agcgattgag cgggttactg ctttccggcg gaattttgcc acggatccag tagcccatca
    36361 ggatcgggat cactacgatc gccagtagcg ccgcgcccgc catcgcatag gttttggtga
    36421 acgccagcgg gccaaacaga cgaccttcct gcccttccag ggtgaagatc gggataaacg
    36481 acagcgtgat aatcagcaga ctgataaaca gcgccggccc cacttcaaca gatgcatcgg
    36541 taatcacctg ccagcgcgtt ttattatcca gcgtggcgtc aggatgctgg tgctgccact
    36601 cttccagccg tttatgcgca ttctcgatca tgacgatagc ggcatcgacc atcgccccga
    36661 cggcaatcgc aataccgccc agcgacataa tattggcgtt cagtccctga aagtgcatga
    36721 caataaaagc aatacacaac cccagcggca acgaaataat cgccaccagc gccgagcgca
    36781 catgccagag aaacagcgca cagactaccg ccaccacaat aaactcttcc agcaacttgc
    36841 cactgaggtt gtcaatggcg cggtcaatga gctggctgcg atcgtatgtt gtaactatct
    36901 ccacgccttc cggcagactg cttttcagcg tttccagttt gtccttcacg gcagcgatca
    36961 cttcacgggc gtttttgccg gaacgcagga tcaccacccc gcccgccact tcgccttcgc
    37021 cgttcagttc ggtaatgccc cggcgcatct ccgggccaac ctggaccttc gcaacatcac
    37081 gcagataaac gggcacgcca ttttcactgg cttttaaaac gatgtgatta aagtcgtcga
    37141 gcgtttgcag atatccgctg gcgcgcacca tatattccgc ttccgccagt tcgatcgacg
    37201 aaccgcccgc ttcctggttt gaagcatcca gcgcgctttt tacttcggcg agactgatgc
    37261 catactgcgc caggcgctga ggatcgataa ccacctgata ctctttcacc acaccgccca
    37321 ccgacgccac ttccgcaacg tcagggatgg tttttagctc atatttgaga aaccagtcct
    37381 gcaatgagcg taaatcggcc agatcgtgct taccgctgcg atctaccagt gcatattcat
    37441 agatccagcc aacgcccgtg gcgtctggcc ccagctcggc gctgactccc gcaggcagct
    37501 tcccctgtac ctgattgagg tactccagca cccgcgagcg cgcccagtac ggatcggtgc
    37561 catcttcaaa aatgacatac acataagagt cgccaaactg cgagaaaccg cgcactgtct
    37621 tcgcgccagg taccgacaac atggtggtgg ttagcggata agtcacctga ttttcaacga
    37681 tttgcggtgc ctgaccggga tagctggttt taataatcac ctgtacatca gagagatccg
    37741 gcagcgcatc cactggcgtg ttaatgatgg tccaggtgcc ccagatgctc agaaacaacg
    37801 cgcccatcag caccagaaaa cggttcgcca ccgagcgacg aataatccat tcaatcattg
    37861 gttattccct caatacgcat gggtagcact ttcagagcgc atccgctcca gtgcgccaga
    37921 aatattggct tcagaatcaa tcaggaacag gccgctggaa accacctttt caccttccgc
    37981 cagaccagag cgtaacgcgg tgacgccttg cgatgcctgg aaaacggcaa cgcgtttcgg
    38041 tacaaagcgc ccgtcagcat caacggtaat cacccgctgt tcgttgccgg tatcaatcag
    38101 cgcctgtgac ggaatgagca gcatcggttc gctggcggta ttgagttgca accaggcgtt
    38161 catgcccggt tttagcgcct cgtcggcgtt gtcgacttcc agacgcagtt gcagcgtgcg
    38221 ggtcgcggca tccacgccgg gtagcagcgt ccatttgcga atggtgagtg ttttatcagg
    38281 tcgcgccgga acggtgagcg taaactgcga ggcatctttc accagccagg cgatggactc
    38341 cgggatcgca gcagtgaccc acaccgggtc cataccctga attttcgcga ccacgttatc
    38401 tttggcgata ttcattcccg cgcgcagatc aaacgcggtg atcacgccat caatgggcgc
    38461 tttgagcgta aagcgagtct ggattttttg cgtggcgatc aggcggcgaa tatccgcctc
    38521 cggcattccc gccagtctca gccgctcaag aatgccttca gtctgggtcg ccgtaccgcc
    38581 ggtttcgcgc agcagtaaat actcactctg cgcttccacc cagtcgggaa tggtcaggtc
    38641 gagaagcggt gtgccctttt gtactttatc gcccacggta agcggataca ccttatcgat
    38701 aaacccggca gcgcgagcct gcacaatggc atactgatac tcgttgtaac tgacattcgc
    38761 cgggaaactc tgggcaaaag tcagcggccc gcgcgtgacg gtcgccgttt tcacccccag
    38821 attctgcgtc tgggtcgggt caatgcgtac accagacgca gaactctctt catcggcata
    38881 tttcggcacc agatccatat ccataaacgg cgatttacct ggtttatcga accgcgtatt
    38941 gggatacatc gggtcgtacc agaataagat tttacgttct gcggtcggcg ttttttctgc
    39001 gggcggttca gcctttgcaa accaggtaaa acctgccgca gaaataatac cgcccgcaat
    39061 catgctgccg ataataagcg cgattttttt catctcatta aacctgggtt actggctgac
    39121 tttaatatcc tgtaataaag aaaggttgcc ctgctggaca aaattaaacg ccactttgtc
    39181 gccggtttta atttcgctca ttttcgtctg cggggtgatg gtaaagcgca tggtcatctc
    39241 cggccagttc acggcagcaa tcggatcgtg atggatggtg atttttttgc tttccagatc
    39301 aacacctttt accacgccag tggcgctaat aacctgtggt tgtgcttcgc tcatggtttc
    39361 atgatgatgt tcgttagcct gggcattaaa gccaataacg gtaaacagac tgaacatcgc
    39421 gacttgcagt gcttttttca tttattctct cctggagtta aaaattattg ctgccaaccg
    39481 ccccctaagg cggtatataa agaaatttcg ttaacctgac gggcataatt caggtcaagt
    39541 aaagtttgtc gggttgcaaa taaagaacgc tcggcatcca gcacttccag ataacttact
    39601 gcgccgtgct gatataatgc ccgcgcccgt tgcaaagtaa ttttcagcga tgccagataa
    39661 cgctgctggg cgctgatttg atcgttcagg ctttgacgta atgccagcgc atctgccact
    39721 tctttaaagg cattctggat tttctgttca taattcacca ccgactgctg ctggcgaatt
    39781 tcggcgatat ccagattggc ctggttgcgt ccggcattaa aaatggggat ctcaattttg
    39841 ggtataaaat tccacatccc gctgctggcg ttaaataatg acgacagatc gctactggcg
    39901 gtcgatattc cgctggtcag gctgatagac gggaaaaatg ccgcgcgtgc agcgccaata
    39961 ttggcattag ccgccattaa cgcgtgttca gcttccataa tatcagggcg ctgcaataag
    40021 atttgcgacg acaagcccgc cggtaattta acgctttgca ggctgtcgct gtttactgtc
    40081 tgcgcttgcg gcagcttgcc gtagcttccc aataacagtt gcaatgcatt attcgcctgc
    40141 gccagttccc cctgacgttt agcgatgtcg ctgcgggtac tttctatcac cccgcgagcc
    40201 tgttctagcg ccagaacatt gctgctaccg gtcaacagtt gtttttcgac aaatgcatat
    40261 gactgctgat aattacgcag cgtttcttcg gctatttgca cttgcgcata cgccagttgc
    40321 tgattgaaat agctttgcgc gacattagaa accagcagaa tatgcaccgc gcgctgagct
    40381 tcctcagtag ctaaataatt ttgacgctcg gcttcgctca tgttctttaa gcgcccgaaa
    40441 aaatcgaggt caaagctggc gttaaggccg gtcgaaaact cccgtgtcgt ggcggtattc
    40501 cctttaagat taccgctcca gctgccgctg ccctcgccat tgagctgtgg gtagcggtcg
    40561 gcatcggtca gacgatattg cgcccgtgcc tcctgcactt tcagcgccgc catgcgtaaa
    40621 tcccggttat tcaccaacgc ctcgctaatc agcgtcttca cctgattatc aacaaaaaag
    40681 gtgcgccagc ccgcgttctg gtagttatct gctgcgttaa ccaggccgtt ctggctgagt
    40741 gagaactgct gcggcacggg cattgccgga cgctgataat ccggtgccag tgaacaaccg
    40801 gttagcgcaa gggccacaca aaatggcaga agtttacaag gagacatagg ctcataattt
    40861 ctggtgattt tatgccgcca actttactcg ccaggctctg attttccggt gacaggaaaa
    40921 tgacaaaatt gtcattttgc caataagcga ttgccatctg atcccgctac tctagaattg
    40981 cccgggcaac atgcggagga aatatgaaac tgttgattgt cgaagatgaa aagaaaaccg
    41041 gagaatactt gaccaaaggg ttaaccgaag ccggttttgt ggtcgatttg gccgacaacg
    41101 ggctgaatgg ctaccatctg gcgatgaccg gtgattatga tctgataatc ctcgatatta
    41161 tgctgccgga cgtgaacggc tgggatatcg tgcgcatgtt gcgttccgcc aataagggga
    41221 tgccgattct gttgcttacc gcgcttggca ccattgaaca tcgcgtcaag gggctggagt
    41281 tgggggcgga tgactatctg gttaagccgt tcgcttttgc tgaactgctg gcgcgggtgc
    41341 gcactctact gcggcgcggg gcggcggtga ttatcgaaag tcagtttcag gttgccgatc
    41401 tgatggtcga tctcgtcagc cgcaaagtca cccgtagcgg cacgcgcatc acgttgacca
    41461 gtaaagaatt tactttgctg gagtttttcc tccgccatca gggtgaagtg ctgccccgct
    41521 cgcttatcgc ctcgcaggtg tgggacatga atttcgacag cgacactaac gccattgatg
    41581 tggcggtgaa gcggctacgc ggcaaaatcg acaacgactt tgagccgaag ctgattcaga
    41641 ccgtgcgcgg cgtgggctat atgcttgagg tgccggatgg tcagtaagcc atttcagcgc
    41701 ccgttttcgc tggcaacccg tctgaccttt tttatcagcc tggccaccat cgcggcgttt
    41761 ttcgcctttg catggatcat gatccactca gtgaaagtgc attttgccga gcaggatatt
    41821 aatgatttaa aagaaattag cgccaccctt gaacgggtac ttaatcatcc tgacgagacg
    41881 caagcccgac gcttaatgac gctggaagat atcgtcagtg gttattccaa cgtgttgatt
    41941 tccctggcag atagccacgg caaaacggtg tatcactccc ccggtgcgcc ggatatccgc
    42001 gagtttacgc gtgacgccat acccgataaa gacgctcagg gtggcgaggt gtatctcctt
    42061 tccggcccga cgattatgat gccaggccac ggtcacgggc atatggaaca cagcaactgg
    42121 cggatgatta acttgccggt tggcccgttg gtggacggca aaccgattta tacgctctac
    42181 atcgcgcttt cgatcgattt tcatcttcat tacataaatg atttgatgaa taaacttatt
    42241 atgaccgcat cgatcatcag catcctgatc gtctttatcg tgctgctggc ggtacataaa
    42301 ggccacgcgc caattcgcag cgtcagccgt caaatccaga acattacctc gaaagatctc
    42361 gacgttcgcc tcgatccaca gaccgtgccc attgaactcg aacaactggt gctgtcgttc
    42421 aaccatatga tcgagcgtat cgaggatgtc tttacccgcc agtccaattt ctcagcggat
    42481 atcgctcacg aaattcgcac gccgattacg aatctcataa cgcaaacgga aatcgccctc
    42541 agccagtcgc gcagtcagaa ggagctggaa gatgtgctct actctaatct cgaagagctg
    42601 actcgaatgg cgaaaatggt cagcgatatg ctgtttctcg ctcaggccga taacaaccag
    42661 ttaatccccg aaaagaaaat gctcaacctg gcggatgaag tcggcaaagt gttcgatttt
    42721 ttcgaggcgt tagcggaaga tcgcggcgtg gagttgcggt ttgttggtga cgagtgtcag
    42781 gttgcgggcg atccgctgat gttgcgtcgg gcgttaagca acctgctttc gaacgccctg
    42841 cgttatacgc cacccggaga ggcaattgtt gtgcgctgcc agacggtcga tcaccaggtg
    42901 caagtttccg tcgaaaaccc cggtacgccc attgcgcccg aacacttacc gcgattgttt
    42961 gaccgtttct accgcgttga tccttcccgc cagcgaaaag gcgaaggtag cggcattggg
    43021 ctggcgatag tgaaatcaat tgttgtcgcg cataaaggca cggttgcagt aacgtcagat
    43081 gcgcggggaa caaggtttat gatcaaacta ccggagaaag gttaattagt tagttcaaac
    43141 tcaaagagtg atgtatcgcc ttctgttatt atttatcaat aaaacaggga agaccttatt
    43201 ggtcgtctga aatcgaaggt tattcatttt cggatattta cgagatattt agatatgcaa
    43261 tttaatc
//
LOCUS       DADXDL010000030        42959 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.030, whole genome shotgun sequence.
ACCESSION   DADXDL010000030 DADXDL010000000
VERSION     DADXDL010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42959
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.030"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1238)
                     /gene="amiC"
                     /locus_tag="IRB70_001947"
     CDS             complement(<1..1238)
                     /gene="amiC"
                     /locus_tag="IRB70_001947"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311701.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiC"
                     /protein_id="HBC0631864.1"
                     /translation="MSGSNTAISRRRLLQGAGAMWLLSVSQVSLAAVSQVVAVRVWPA
                     SSYTRVTVESNRQLKYKQFALSNPERVVVDIEDVNLNSVLKGMAAQIRADDPFIKSAR
                     VGQFDPQTVRMVFELKQNVKPQLFALAPVAGFKERLVMDLYPANAQDMQDPLLALLED
                     YNKGDLEKQVPPAQSGPQPGKAGRDRPIVIMLDPGHGGEDSGAVGKYKTREKDVVLQI
                     ARRLRSLIEKEGNMKVYMTRNEDIFIPLQVRVAKAQKQRADLFVSIHADAFTSRQPSG
                     SSVFALSTKGATSTAAKYLAQTQNASDLIGGVSKSGDRYVDHTMFDMVQSLTIADSLK
                     FGKAVLNKLGKINKLHKNQVEQAGFAVLKAPDIPSILVETAFISNVEEERKLKTATFQ
                     QEVAESILAGIKAYFADGATL"
     gene            1470..2801
                     /gene="argA"
                     /locus_tag="IRB70_001948"
     CDS             1470..2801
                     /gene="argA"
                     /locus_tag="IRB70_001948"
                     /EC_number="2.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino-acid N-acetyltransferase"
                     /protein_id="HBC0631865.1"
                     /translation="MVKERKTELVEGFRHSVPYINTHRGKTFVIMLGGEAIEHENFSS
                     IVNDIGLLHSLGIRLVVVYGARPQIDANLAAHHHEPLYHKNIRVTDAQTLELVKQAAG
                     TLQLDITARLSMSLNNTPLQGAHINVVSGNFIIAQPLGVDDGVDYCHSGRIRRIDEDA
                     IHRQLDSGAIVLMGPVAVSVTGESFNLTSEEIATQLAIKLKAEKMIGFCSSQGVTNDD
                     GDIVSELFPNEAQARVEAQEEKGDYNSGTVRFLRGAVKACRSGVRRCHLISYQEDGAL
                     LQELFSRDGIGTQIVMESAEQIRRATINDIGGILELIRPLEQQGILVRRSREQLEMEI
                     DKFTIIQRDNTTIACAALYPFPEEKIGEMACVAVHPDYRSSSRGEVLLERIAAQAKQS
                     GLSKLFVLTTRSIHWFQERGFTPVDIDLLPESKKQLYNYQRKSKVLMADLG"
     gene            complement(2883..4709)
                     /gene="recD"
                     /locus_tag="IRB70_001949"
     CDS             complement(2883..4709)
                     /gene="recD"
                     /locus_tag="IRB70_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit alpha"
                     /protein_id="HBC0631866.1"
                     /translation="MKLQKQLLEAVEHKQLRPLDVQFALTVAGDEHPAVTLAAALLSH
                     DAGEGHVCLPLSRLENNEASHPLLATCVSEIGELQNWEECLLASQAVSRGDEPTPMIL
                     CGDRLYLNRMWCNERTVARFFNEVNHAIEVDEALLAQTLDKLFPVSDEINWQKVAAAV
                     ALTRRISVISGGPGTGKTTTVAKLLAALIQMADGERCRIRLAAPTGKAAARLTESLGK
                     ALRQLPLTDEQKKRIPEDASTLHRLLGAQPGSQRLRHHAGNPLHLDVLVVDEASMIDL
                     PMMSRLIDALPDHARVIFLGDRDQLASVEAGAVLGDICAYANAGFTAERAGQLSRLTG
                     THVPAGTGTEAASLRDSLCLLQKSYRFGSDSGIGQLAAAINRGDKTAVKTVFQQDFSD
                     IEKRLLQSGEDYIAMLEEALAGYGRYLDLLQARAEPDLIIQAFNEYQLLCALREGPFG
                     VAGLNERIEQFMQQKRKIHRHPHSRWYEGRPVMIARNDSALGLFNGDIGIALDRGQGT
                     RVWFAMPDGNIKSVQPSRLPEHETTWAMTVHKSQGSEFDHAALILPSQRTPVVTRELV
                     YTAVTRARRRLSLYADERILSAAIATRTERRSGLAALFSSRE"
     gene            complement(4709..8251)
                     /gene="recB"
                     /locus_tag="IRB70_001950"
     CDS             complement(4709..8251)
                     /gene="recB"
                     /locus_tag="IRB70_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit beta"
                     /protein_id="HBC0631867.1"
                     /translation="MSDVAETLDPLRLPLQGERLIEASAGTGKTFTIAALYLRLLLGL
                     GGSAAFPRPLTVEELLVVTFTEAATAELRGRIRSNIHELRIACLRETTDNPLYKRLLE
                     EIDDKAQAAQWLLLAERQMDEAAVFTIHGFCQRMLNLNAFESGMLFEQQLIEDESLLR
                     YQACADFWRRHCYPLPREIAQVVFETWKGPQALLRDINRYLQGEAPVIKAPPPDDETL
                     ASRHAQIVARIDTVKQQWRDAVGELDALIESSGIDRRKFNRSNQAKWIDKISAWAEEE
                     TNSYQLPESLEKFSQRFLEDRTKAGGETPRHPLFEAIDQLLAEPLSIRDLVITRALAE
                     IRETVAREKRRRGELGFDDMLSRLDSALRSESGEVLAAAIRTRFPVAMIDEFQDTDPQ
                     QYRIFRRIWHHQPETALLLIGDPKQAIYAFRGADIFTYMKARSEVHAHYTLDTNWRSA
                     PGMVNSVNKLFSQTDDAFMFREIPFIPVKSAGKNQALRFVFKGETQPAMKMWLMEGES
                     CGVGDYQSTMAQVCAAQIRDWLQAGQRGEALLMNGDDARPVRASDISVLVRSRQEAAQ
                     VRDALTLLEIPSVYLSNRDSVFETLEAQEMLWLLQAVMTPERENTLRSALATSMMGLN
                     ALDIETLNNDEHAWDAVVEEFDGYRQIWRKRGVMPMLRALMSARNIAENLLATAGGER
                     RLTDILHISELLQEAGTQLESEHALVRWLSQHILEPDSNASSQQMRLESDKHLVQIVT
                     IHKSKGLEYPLVWLPFITNFRVQDQAFYHDRHSFEAVLDLNAAPESVDLAEAERLAED
                     LRLLYVALTRSVWHCSLGVAPLVRRRGDKKGDTDVHQSALGRLLQKGEPQDAAGLRTC
                     IEALCDDDIAWQTAQTGDNQPWQVNDALTAELNARTLQRLPGDNWRVTSYSGLQQRGH
                     GIAQDLMPRLDVDAAGVVSVVEEPTLTPHQFPRGASPGTFLHSLFEDLDFTQPVDPNW
                     VQEKLELGGFEPQWEPVLTEWITAVLQAPLNETGVSLNQLSDRDKQVEMEFYLPISEP
                     LIASQLDALIRQFDPLSAGCPPLEFMQVRGMLKGFIDLVFRHEGRYYLLDYKSNWLGE
                     DSSAYTQQAMAAAMQAHRYDLQYQLYTLALHRYLRHRIADYDYERHFGGVIYLFLRGV
                     DKEHPQQGIYATRPNAGLIDLMDEMFAGMTLEEA"
     gene            complement(8244..11132)
                     /gene="ptrA"
                     /locus_tag="IRB70_001951"
     CDS             complement(8244..11132)
                     /gene="ptrA"
                     /locus_tag="IRB70_001951"
                     /EC_number="3.4.24.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pitrilysin"
                     /protein_id="HBC0631868.1"
                     /translation="MPRSIWFKALLLFVALWAPLSQAETGWQPIQETIRKSDKDNRQY
                     QAIRLDNGMVVLLVSDPQAVKSLSALVVPVGSLEDPEAYQGLAHYLEHMSLMGSKKYP
                     QADSLAEYLKMHGGSHNASTAPYRTAFYLEVENDALPGAVDRLADAIAEPLLDKKYAE
                     RERNAVNAELTMARTRDGMRMAQVSAETINPAHPGSKFSGGNLETLSDKPGNPVQQAL
                     KDFHEKYYSANLMKAVIYSNKPLPELAKMAADTFGRVPNKESKKPEITVPVVTDAQKG
                     IIIHYVPALPRKVLRVEFRIDNNSAKFRSKTDELITYLIGNRSPGTLSDWLQKQGLVE
                     GISANSDPIVNGNSGVLAISASLTDKGLANRDQVVAAIFSYLNLLREKGIDKQYFDEL
                     ANVLDIDFRYPSITRDMDYVEWLADTMIRVPVEHTLDAVNIADRYDAKAVKERLAMMT
                     PQNARIWYISPKEPHNKTAYFVDAPYQVDKISAQTFADWQKKAADIALSLPELNPYIP
                     DDFSLIKSEKKYDHPELIVDESNLRVVYAPSRYFSSEPKADVSLILRNPKAMDSARNQ
                     VMFALNDYLAGLALDQLSNQASVGGISFSTNANNGLMVNANGYTQRLPQLFQALLEGY
                     FSYTATEDQLEQAKSWYNQMMDSAEKGKAFEQAIMPAQMLSQVPYFSRDERRKILPSI
                     TLKEVLAYRDALKSGARPEFMVIGNMTEAQATTLARDVQKQLGADGSEWCRNKDVVVD
                     KKQSVIFEKAGNSTDSALAAVFVPTGYDEYTSSAYSSLLGQIVQPWFYNQLRTEEQLG
                     YAVFAFPMSVGRQWGMGFLLQSNDKQPSFLWERYKAFFPTAEAKLRAMKPEEFAQIQQ
                     AVITQMLQAPQTLGEEASKLSKDFDRGNMRFDSRDKIVAQIKLLTPQKLADFFHQAVV
                     EPQGMAILSQISGSQNGKAEYVHPEGWKVWENVSALQQTMPLMSEKNE"
     gene            complement(11308..14676)
                     /gene="recC"
                     /locus_tag="IRB70_001952"
     CDS             complement(11308..14676)
                     /gene="recC"
                     /locus_tag="IRB70_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease V subunit gamma"
                     /protein_id="HBC0631869.1"
                     /translation="MLRVYHSNRLDVLEALMEFIVERERLDDPFEPEMILVQSTGMAQ
                     WLQMTLSQKFGIAANIDFPLPASFIWDMFVRVLSEIPKESAFNKQSMSWKLMTLLPQL
                     LDREDFTLLRHYLTDDSDKRKLFQLSSKAADLFDQYLVYRPDWLAQWETGHLVEGLGE
                     AQAWQAPLWKALVEYTHQLGQPRWHRANLYQRFIETLESATTCPPGLPSRVFICGISA
                     LPPVYLQALQALGKHIEIHLLFTNPCRYYWGDIKDPAYLAKLLTRQRRHSFEDRELPL
                     FRDSENAGQLFNSDGEQDVGNPLLASWGKLGRDYIYLLSDLESSQELDAFVDVTPDNL
                     LHNIQSDILELENRAVAGVNIEEFSRSDNKRPLDPLDSSITFHVCHSPQREVEVLHDR
                     LLAMLEEDPTLTPRDIIVMVADIDSYSPFIQAVFGSAPADRYLPYAISDRRARQSHPV
                     LEAFISLLSLPDSRFVSEDVLALLDVPVLAARFDITEEGLRYLRQWVNESGIRWGIDD
                     DNVRELELPATGQHTWRFGLTRMLLGYAMESAQGEWQSVLPYDESSGLIAELVGHLAS
                     LLMQLNIWRRGLAQERPLEEWLPVCRDMLNAFFLPDAETEAAMTLIEQQWQAIIAEGL
                     GAQYGDAVPLSLLRDELAQRLDQERISQRFLAGPVNICTLMPMRSIPFKVVCLLGMND
                     GVYPRQLAPLGFDLMSQKPKRGDRSRRDDDRYLFLEALISAQQKLYISYIGRSIQDNS
                     ERFPSVLVQELIDYIGQSHYLPGDEALNCDESEARVKAHLTCLHTRMPFDPQNYQPGE
                     RQSYAREWLPAASQAGKAHSEFVQPLPFTLPETVPLETLQRFWAHPVRAFFQMRLQVN
                     FRTEDSEIPDTEPFILEGLSRYQINQQLLNALVEQDDAERLFRRFRAAGDLPYGAFGE
                     IFWETQCQEMQQLADRVIACRQPGQSMEIDLACNGVQITGWLPQVQPDGLLRWRPSLL
                     SVAQGMQLWLEHLVYCASGGNGESRLFLRKDGEWRFPPLAAEQALHYLSQLIEGYREG
                     MSAPLLVLPESGGAWLKTCYDAQNDAMLDDDSTLQKARTKFLQAYEGNMMVRGEGDDI
                     WYQRLWRQLTPETMEAIVEQSQRFLLPLFRFNQS"
     gene            complement(14689..15012)
                     /locus_tag="IRB70_001953"
     CDS             complement(14689..15012)
                     /locus_tag="IRB70_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBC0631870.1"
                     /translation="MSASLKNQQGFSLPEVMLAMVLMVMIVTALSGFQRTLMNSLASR
                     NQYQQLWRHGWQQTQLRAISPPANWQVNRMQTSQAGCVSISVTLVSPGGREGEMTRLH
                     CPNRQ"
     gene            complement(14997..15404)
                     /locus_tag="IRB70_001954"
     CDS             complement(14997..15404)
                     /locus_tag="IRB70_001954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311708.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2509 family protein"
                     /protein_id="HBC0631871.1"
                     /translation="MNREKGVSSLALVLMLLILGSLLLQGMSQQDRSFASRVSMESQS
                     LRRHAIVQSALEWGKMHSWQTQPAVQCLLYAATGARVCLRLLADNEALLIAGYEGVSL
                     WRTGEVIDGNIVFSPRGWSDFCPLKERALCQLP"
     gene            complement(15401..15964)
                     /locus_tag="IRB70_001955"
     CDS             complement(15401..15964)
                     /locus_tag="IRB70_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HBC0631872.1"
                     /translation="MPVKEQGFSLLEVLIAMAISSVLLLGAARFLPALQRDSLTSTRK
                     LALEDEIWLRVFTVAKHLQRAGYCHGSCTGEGLEIVGQGDCVIVQWDANSNGIWDREP
                     VKESDQIGFRLKEHVLETLRGATSCEGKGWDKVTNPDAIIIDTFQVVRQDVSGFSPVL
                     TVNMHAASKADPQTVVDASYSVTGSNL"
     gene            complement(15955..16425)
                     /locus_tag="IRB70_001956"
     CDS             complement(15955..16425)
                     /locus_tag="IRB70_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase-dependent protein"
                     /protein_id="HBC0631873.1"
                     /translation="MKTQRGYTLIETLVAMLILVMLSASGLYGWQYWQQSQRLWQTAS
                     QARDYLLYLREDANWHNRDHSISVIREGTLWCLVSSAAGANTCHGSSPLVFVPRWPEV
                     EMSDLTPSLAFFGLRNTAWAGHIRFKNSTGEWWLVVSPWGRLRLCQQGETEGCL"
     gene            complement(16610..17404)
                     /gene="thyA"
                     /locus_tag="IRB70_001957"
     CDS             complement(16610..17404)
                     /gene="thyA"
                     /locus_tag="IRB70_001957"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBC0631874.1"
                     /translation="MKQYLELMQKVLDEGTQKNDRTGTGTLSIFGHQMRFNLQDGFPL
                     VTTKRCHLRSIIHELLWFLQGDTNIAYLHENNVTIWDEWADENGDLGPVYGKQWRAWP
                     TPDGRHIDQITTVLNQLKNDPDSRRIIVSAWNVGELDKMALAPCHAFFQFYVADGKLS
                     CQLYQRSCDVFLGLPFNIASYALLVHMMAQQCDLEVGDFVWTGGDTHLYSNHMDQTHL
                     QLSREPRPLPKLIIKRKPESIFDYRFEDFEIEGYDPHPGIKAPVAI"
     gene            complement(17411..18286)
                     /gene="lgt"
                     /locus_tag="IRB70_001958"
     CDS             complement(17411..18286)
                     /gene="lgt"
                     /locus_tag="IRB70_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBC0631875.1"
                     /translation="MTSSYLHFPEFDPVIFSIGPVALHWYGLMYLVGFIFAMWLATRR
                     ANRPGSGWTKNEVENLLYAGFLGVFLGGRIGYVLFYNFPQFMADPLYLFRVWDGGMSF
                     HGGLIGVIVVMIIFARRTKRSFFQVSDFIAPLIPFGLGAGRLGNFINGELWGRVDPNF
                     PFAMLFPGSRTEDILLLQTNPQWQSIFDTYGVLPRHPSQLYELLLEGVVLFIILNLYI
                     RKPRPMGAVSGLFLIGYGAFRIIVEFFRQPDAQFTGAWVQYISMGQILSIPMIVAGVI
                     MMVWAYRRSPQQHVS"
     gene            complement(18437..20683)
                     /gene="ptsP"
                     /locus_tag="IRB70_001959"
     CDS             complement(18437..20683)
                     /gene="ptsP"
                     /locus_tag="IRB70_001959"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBC0631876.1"
                     /translation="MLTRLREIVEKVASAPRLNEALNILVTDICLAMDTEVCSVYLAD
                     HDRRCYYLMATRGLKKPRGRTVTLAFDEGIVGLVGRLAEPINLADAQKHPSFKYVPSV
                     KEERFRAFLGVPIIQRRQLLGVLVVQQRELRQYDESEESFLVTLATQMAAILSQSQLT
                     ALFGQYRQTRIRALPAAPGVAIAEGWQDATLPLMEQVYQASTLDPALERERLTGALEE
                     AANEFRRYSKRFAAGAQKETAAIFDLYSHLLSDTRLRRELFAEVDKGSVAEWAVKTVI
                     EKFAEQFAALSDNYLKERAGDLRALGQRLLFHLDDANQGPNAWPERFILVADELSATT
                     LAELPQDRLVGVVVRDGAANSHAAIMVRALGIPTVMGADIQPSVLHRRTLIVDGYRGE
                     LLVDPEPVLLQEYQRLISEEIELSRLAEDDVNLPAQLKSGERIKVMLNAGLSPEHEEK
                     LGSRIDGIGLYRTEIPFMLQSGFPSEEEQVAQYQGMLQMFNDKPVTLRTLDVGADKQL
                     PYMPISEENPCLGWRGIRITLDQPEIFLIQVRAMLRANAATGNLNILLPMVTSLDEVD
                     EARRLIERAGREVEEMIGYEIPKPRIGIMLEVPSMVFMLPHLAKRVDFISVGTNDLTQ
                     YILAVDRNNTRVANIYDSLHPAMLRALAMIAREAEIHGIDLRLCGEMAGDPMCVAILI
                     GLGYRHLSMNGRSVARVKYLLRRIDFAEAENLAQRSLEAQLATEVRHQVAAFMERRGM
                     GGLIRGGL"
     gene            complement(20696..21226)
                     /gene="rppH"
                     /locus_tag="IRB70_001960"
     CDS             complement(20696..21226)
                     /gene="rppH"
                     /locus_tag="IRB70_001960"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001655775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA pyrophosphohydrolase"
                     /protein_id="HBC0631877.1"
                     /translation="MIDDDGYRPNVGIVICNRQGQVMWARRFGQHSWQFPQGGINPGE
                     SAEQAMYRELFEEVGLSRKDVRILASTRNWLRYKLPKRLVRWDTKPVCIGQKQKWFLL
                     QLVSGDAEINMQTSSTPEFDGWRWVSYWYPVRQVVSFKRDVYRKVMKEFASVVMSLQE
                     NTPKPQNASAYRRKRG"
     gene            21911..22600
                     /gene="mutH"
                     /locus_tag="IRB70_001961"
     CDS             21911..22600
                     /gene="mutH"
                     /locus_tag="IRB70_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutH"
                     /protein_id="HBC0631878.1"
                     /translation="MSQPRPLLSPPETEEQLLAQAQQLSGYTLGELAALAGLVTPENL
                     KRDKGWIGVLLEIWLGASAGSKPEQDFAALGVELKTIPVDSLGRPLETTFVCVAPLTG
                     NSGVTWETSHVRHKLKRVLWIPVEGERSIPLAQRRVGSPLLWSPNEEEDRQLREDWEE
                     LMDMIVLGQVERITARHGEYLQIRPKAANAKALTEAIGARGERILTLPRGFYLKKNFT
                     SALLAHHFLIQ"
     gene            22669..23382
                     /locus_tag="IRB70_001962"
     CDS             22669..23382
                     /locus_tag="IRB70_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HBC0631879.1"
                     /translation="MLFAWITDPNAWLALGTLTLLEIVLGIDNIIFLSLVVAKLPTAQ
                     RAHARRLGLAGAMVMRLALLASIAWVTRLTNPLFTIFSQEISARDLILLLGGLFLIWK
                     ASKEIHESIEGEEEGLKTRVSSFLGAIVQIMLLDIIFSLDSVITAVGLSDHLFIMMAA
                     VVIAVGVMMFAARSIGDFVERHPSVKMLALSFLILVGFTLILESFDIHVPKGYIYFAM
                     FFSIAVESLNLIRNKKNPL"
     gene            23520..23738
                     /gene="ygdR"
                     /locus_tag="IRB70_001963"
     CDS             23520..23738
                     /gene="ygdR"
                     /locus_tag="IRB70_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YgdR"
                     /protein_id="HBC0631880.1"
                     /translation="MKKWAVIISAVGLAFAVSGCSSDYVMATKDGRMILTDGKPEIDD
                     DTGLVSYHDQQGNAMQINRDDVSQIIER"
     gene            23846..24886
                     /locus_tag="IRB70_001964"
     CDS             23846..24886
                     /locus_tag="IRB70_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(H)-dependent aldo-keto reductase"
                     /protein_id="HBC0631881.1"
                     /translation="MQYHRIPHSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGI
                     NLIDVAEMYPVPPRPETQGLTETYVGNWLAKHGSREKLIIASKVSGPSRNNDKGIRPD
                     QALDRKNIREALHDSLKRLQTDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPAVSLLDT
                     LDALAEYQRAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVG
                     LAEVSQYEGVELLAYSSLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAA
                     YVDIARRHGLDPAQMALAFVRRQPFVASTLLGATTMEQLKTNVESLHLELSEDVLAEI
                     EAVHQVYTYPAP"
     gene            complement(24918..26111)
                     /gene="lplT"
                     /locus_tag="IRB70_001965"
     CDS             complement(24918..26111)
                     /gene="lplT"
                     /locus_tag="IRB70_001965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysophospholipid transporter LplT"
                     /protein_id="HBC0631882.1"
                     /translation="MSESVHTNTSLWSKGMKAVIVAQFLSAFGDNALLFATLALLKAQ
                     FYPEWSQPILQMVFVGAYILFAPFVGQVADSFAKGRVMMFANGLKLLGAASICFGINP
                     FLGYTLVGVGAAAYSPAKYGILGELTTGSKLVKANGLMEASTIAAILLGSVAGGVLAD
                     WHVLVALAACALAYGGAVVANIYIPKLAAARPGQSWNLINMTRSFLNACTSLWRNGET
                     RFSLVGTSLFWGAGVTLRFLLVLWVPVALGITDNATPTYLNAMVAIGIVVGAGAAAKL
                     VTLETVSRCMPAGILIGVVVLIFSLQHELLPAYALLMLIGVLGGFFVVPLNALLQERG
                     KKSVGAGNAIAVQNLGENSAMLLMLGIYSLAVMVGVPVVPIGIGFGALFALAITALWI
                     WQRRH"
     gene            complement(26104..28263)
                     /gene="aas"
                     /locus_tag="IRB70_001966"
     CDS             complement(26104..28263)
                     /gene="aas"
                     /locus_tag="IRB70_001966"
                     /EC_number="2.3.1.40"
                     /EC_number="6.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acyl-ACP--phospholipid
                     O-acyltransferase/long-chain-fatty-acid--ACP ligase"
                     /protein_id="HBC0631883.1"
                     /translation="MLFSFFRNVCRVLYRVRVTGDNQALKGERVLITPNHVSFIDGIL
                     LALFLPVRPVFAVYTSISQQWYMRWLKSFIDFVPLDPTQPMAIKHLVRLVEQGRPVVI
                     FPEGRITTTGSLMKIYDGAGFVAAKSGATVIPVRIEGAELTHFSRLKGLVKRRLFPQI
                     TLHILPPTQVQMPDAPRARDRRKIAGEMLHQIMMEARMAVRPRETLYESLLSAMYRFG
                     AGKKCVEDVNFTPDSYRKLLTKTLFVGRILEKYSVEGERIGLMLPNAGISAAVIFGAI
                     ARRRIPAMMNYTAGVKGLTSAITAAEIKTIFTSRQFLDKGKLWHLSEQLTQVRWVYLE
                     DLKADVTTADKVWIFAHLLMPRLAQVKQQPEEEALILFTSGSEGHPKGVVHNHKSILA
                     NVEQIKTIADFTTNDRFMSALPLFHSFGLTVGLFTPLLTGAEVFLYPSPLHYRIVPEL
                     VYDRSCTVLFGTSTFLGHYARFANPYDFYRLRYVVAGAEKLQESTKQLWQDKFGLRIL
                     EGYGVTECAPVVSINVPMAAKPGTVGRILPGMDARLLSVPGIEEGGRLQLKGPNIMNG
                     YLRVEKPGVLEVPTAENVRGEMERGWYDTGDIVRFDEQGFVQIQGRAKRFAKIAGEMV
                     SLEMVEQLALGVSPDKVHATAIKSDASKGEALVLFTTDNELTRDKLQQYAREHGVPEL
                     AVPRDIRYPKQMPLLGSGKPDFVTLKSWVDEAEQHDE"
     gene            28849..29880
                     /gene="galR"
                     /locus_tag="IRB70_001967"
     CDS             28849..29880
                     /gene="galR"
                     /locus_tag="IRB70_001967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator GalR"
                     /protein_id="HBC0631884.1"
                     /translation="MATIKDVARLAGVSVATVSRVINNSPKASEASRLAVHSAMESLS
                     YHPNANARALAQQTTETIGLVVGDVSDPFFGAMVKAVEQVAYHTGNFLLIGNGYHNEQ
                     KERQAIEQLIRHRCAALVVHAKMIPDADLASLMKQMPGMVLINRILPGFENRCIALDD
                     RYGAWLATRHLIQQGHTRIGYLCSNHSISDAEDRLQGYYDALAESGIPANDRLVTFGE
                     PDESGGEQAMTELLGRGRNFTAVACYNDSMAAGAMGVLNDNGIDVPGEISLIGFDDVL
                     VSRYVRPRLTTVRYPIVTMATQAAELALALADNRPLPEITNVFSPTLVRRHSVSTPSL
                     EASHHATSD"
     gene            complement(29887..31149)
                     /gene="lysA"
                     /locus_tag="IRB70_001968"
     CDS             complement(29887..31149)
                     /gene="lysA"
                     /locus_tag="IRB70_001968"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBC0631885.1"
                     /translation="MPHSLFSTDTDLTAENLLRLPAEFGCPVWVYDAQIIRRQIAALK
                     QFDVVRFAQKACSNIHILRLMREQGVKVDSVSLGEIERALAAGYNPQTHPDDIVFTAD
                     VIDQATLERVSELQIPVNAGSVDMLDQLGQVSPGHRVWLRVNPGFGHGHSQKTNTGGE
                     NSKHGIWYTDLPAALDVIQRHHLQLVGIHMHIGSGVDYAHLEQVCGAMVRQVLEFGQD
                     LQAISAGGGLSIPYQQGEEAVDTEHYYGLWNAAREQIARHLGHPVKLEIEPGRFLVAQ
                     AGVLITQVRSVKQMGSRHFVLVDAGFNDLMRPAMYGSYHHISALAADGRSLEHAPTVE
                     TVVAGPLCESGDVFTQQEGGNVETRALPEVKAGDYLVLHDTGAYGASMSSNYNSRPLL
                     PEVLFDNGQARLIRRRQTIEELLALELL"
     gene            31271..32206
                     /gene="lysR"
                     /locus_tag="IRB70_001969"
     CDS             31271..32206
                     /gene="lysR"
                     /locus_tag="IRB70_001969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator LysR"
                     /protein_id="HBC0631886.1"
                     /translation="MAAVNLRHIEIFHAVMTAGSLTEAAHLLHTSQPTVSRELARFEK
                     VIGLKLFERIRGRLHPTVQGLRLFEEVQRSWYGLDRIVSAAESLREFRQGELSIACLP
                     VFSQSFLPQLLQPFLARYPDVSLNIVPQESPLLEEWLSAQRHDLGLTETLHTPAGTER
                     TELLSLDEVCVLPPGHPLAVKKVLTPDDFHGENYISLSRTDSYRQLLDQLFTENQVKR
                     RMIVETHSAASVCAMVRAGVGVSVVNPLTALDYAASGLVVRRFSIAVPFTVSLIRPLH
                     RPSSALVQAFSEHLQAGLPKLVTSLDAILSSATTA"
     gene            complement(32193..32885)
                     /gene="ygeA"
                     /locus_tag="IRB70_001970"
     CDS             complement(32193..32885)
                     /gene="ygeA"
                     /locus_tag="IRB70_001970"
                     /EC_number="5.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid racemase"
                     /protein_id="HBC0631887.1"
                     /translation="MKTIGLLGGMSWESTIPYYRLINEGIKQRLGGLHSAQVLLHSVD
                     FHEIEECQRRGEWDKTGDILAEAALGLQRAGAEGIVLCTNTMHKVADAIESRCSLPFL
                     HIADATGRAITGAGMTRVALLGTRYTMEQDFYRGRLTEQFSINCLIPEADERAKINQI
                     IFEELCLGQFTEASRAYYAQVIARLAEQGAQGVIFGCTEIGLLVPEERSVLPVFDTAA
                     IHAEDAVAFMLS"
     gene            complement(33014..34432)
                     /gene="araE"
                     /locus_tag="IRB70_001971"
     CDS             complement(33014..34432)
                     /gene="araE"
                     /locus_tag="IRB70_001971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-proton symporter AraE"
                     /protein_id="HBC0631888.1"
                     /translation="MVTINTESALTPRSLRDTRRMNMFVSVAAAVAGLLFGLDIGVIA
                     GALPFITDHFVLTSRLQEWVVSSMMLGAAIGALFNGWLSFRLGRKYSLMAGAILFVLG
                     SIGSAFATSVEMLIAARVVLGIAVGIASYTAPLYLSEMASENVRGKMISMYQLMVTLG
                     IVLAFLSDTAFSYSGNWRAMLGVLALPAVLLIILVVFLPNSPRWLAEKGRHIEAEEVL
                     RMLRDTSEKAREELNEIRESLKLKQGGWALFKINRNVRRAVFLGMLLQAMQQFTGMNI
                     IMYYAPRIFKMAGFTTTEQQMIATLVVGLTFMFATFIAVFTVDKAGRKPALKIGFSVM
                     ALGTLVLGYCLMQFDNGTASSGLSWLSVGMTMMCIAGYAMSAAPVVWILCSEIQPLKC
                     RDFGITCSTTTNWVSNMIIGATFLTLLDSIGAAGTFWLYTALNIAFVGITFWLIPETK
                     NVTLEHIERKLMAGEKLRNIGV"
     gene            complement(34747..35508)
                     /gene="kduD"
                     /locus_tag="IRB70_001972"
     CDS             complement(34747..35508)
                     /gene="kduD"
                     /locus_tag="IRB70_001972"
                     /EC_number="1.1.1.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxy-D-gluconate 5-dehydrogenase
                     KduD"
                     /protein_id="HBC0631889.1"
                     /translation="MILSAFSLEGKVAVVTGCDTGLGQGMALGLAQAGCDIVGINIVE
                     PTETIKQVTALGRRFLSLTADLRKIDGIPALLDRAVAEFGHIDILVNNAGLIRREDAL
                     EFSEKDWDDVMNLNIKSVFFMSQAAAKHFIAQGNGGKIINIASMLSFQGGIRVPSYTA
                     SKSGVMGVTRLMANEWAKHNINVNAIAPGYMATNNTQQLRADEQRSAEILDRIPAGRW
                     GLPSDLMGPVVFLASSASDYVNGYTIAVDGGWLAR"
     gene            complement(35538..36374)
                     /gene="kduI"
                     /locus_tag="IRB70_001973"
     CDS             complement(35538..36374)
                     /gene="kduI"
                     /locus_tag="IRB70_001973"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBC0631890.1"
                     /translation="MDVRQSIHSAHAKTLDTQGLRNEFLVEKVFVADEYTMVYSHIDR
                     IIVGGIMPVTKTVSVGGEVGKQLGVSYFLERRELGVINIGGAGTITVDGQCYEIGHRE
                     ALYVGKGAKEVVFASIDTATPAKFYYNCAPAHTTYPTKKVTPDEVSPVTLGDNLTSNR
                     RTINKYFVPDVLETCQLSMGMTELAPGNLWNTMPCHTHERRMEVYFYFNMDDDACVFH
                     MMGQPQETRHIVMHNEQAVISPSWSIHSGVGTKAYTFIWGMVGENQVFDDMDHVAVKD
                     LR"
     gene            complement(36661..37842)
                     /locus_tag="IRB70_001974"
     CDS             complement(36661..37842)
                     /locus_tag="IRB70_001974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417321.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acetyltransferase"
                     /protein_id="HBC0631891.1"
                     /translation="MKDVVIVGALRTPIGCFRGALAGHSAVELGSLVVKALIERTGVP
                     AYAVDEVILGQVLTAGAGQNPARQSAIKGGLPNSVSAITINDVCGSGLKALHLATQAI
                     QCGEADIVIAGGQENMSRAPHVLTDSRTGAQLGNSQLVDSLVHDGLWDAFNDYHIGVT
                     AENLAREYGISRQLQDAYALSSQQKARAAIDAGRFKDEIVPVMTQSNGQTLVVDTDEQ
                     PRTDASAEGLARLNPSFDSLGSVTAGNASSINDGAAAVMMMSEAKARALNLPVLARIR
                     AFASVGVDPALMGIAPVYATRRCLERVGWQLADVDLIEANEAFAAQALSVGKMLEWDE
                     RRVNVNGGAIALGHPIGASGCRILVSLVHEMVKRNARKGLATLCIGGGQGVALTIERD
                     E"
     gene            38097..39326
                     /locus_tag="IRB70_001975"
     CDS             38097..39326
                     /locus_tag="IRB70_001975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HBC0631892.1"
                     /translation="MSNIWSKEETLWSFALYGTAVGAGTLFLPIQLGSAGAVVLFITA
                     LVAWPLTYWPHKALCQFILSSKTSAGEGITGAVTHYYGKKIGNLITTLYFIAFFVVVL
                     IYAVAITNSLTEQLAKHMVIDLRIRMLVSLGVVLILNLIFLMGRHATIRVMGFLVFPL
                     IAYFLFLSIYLVGSWQPDLLTTQVEFNQNTLHQIWISIPVMVFAFSHTPIISTFAIDR
                     REKYGEHAMDKCKKIMKVAYLIICISVLFFVFSCLLSIPPSYIEAAKEEGVTILSALS
                     MLPNAPAWLSISGIIVAVVAMSKSFLGTYFGVIEGATEVVKTTLQQVGVKKSRAFNRA
                     LSIMLVSLITFIVCCINPNAISMIYAISGPLIAMILFIMPTLSTYLIPALKPWRSIGN
                     LITLIVGILCVSVMFFS"
     gene            39786..40418
                     /locus_tag="IRB70_001976"
     CDS             39786..40418
                     /locus_tag="IRB70_001976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417323.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0631893.1"
                     /translation="MGLCSRYKSLTCNSCSMHCQIMPEESPRLQYCANSCFCMWPEES
                     SYFNRGVVEGILTKNHNARLSGYIFVDFSVSFLRLFLEKDWIDYLASTDMGIVLVSDR
                     NMQSLANYWRKHNSAISAVIYNDDGLDVANEKIRQLFIGRYLSFTRGNTLTQMEFTIM
                     GYMVSGYNPYQIAEVLDMDIRSIYAYKQRIEKRMGGKINELFIRSHSVQH"
     gene            40752..41561
                     /locus_tag="IRB70_001977"
     CDS             40752..41561
                     /locus_tag="IRB70_001977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417324.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBC0631894.1"
                     /translation="MYWIINDNIEFWPEHRKLISVHNADLNVVLTTPASRCLSLLLEA
                     FPDVVAQQDFFTRVWEEEGMRVPTNTLYQNISIIRRGFRAVGDTTHSLIATVPRRGFK
                     IHNDINIQNHAINSSTDAHTHNAPPAVKGNAGYKESIGGANNFNNKILKHIKSYLIML
                     SIFAIGVYSAHWLWNNNQPKPFFKDYKTVAEINGCHFNVTEDTIDGLKEFDKYKTRIL
                     DSGINCKKYPWLYFPLAKSSPGMIVMACNKNYNQHEVAGCLTLSYREANRD"
     gene            41554..41976
                     /locus_tag="IRB70_001978"
     CDS             41554..41976
                     /locus_tag="IRB70_001978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417325.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631895.1"
                     /translation="MIDYKKNLLFILVFISGFILFIVYSYTAEKMIYNETCTANWVIF
                     NDKGRANLTIDFMYNQKNKTGTVALSGTWQQGNRESKSIRRNIEYTWIENYDTAHLTS
                     KKVNKFEIMDQVDDDRLAELIPDFYVFPEKSVSYNILK"
     gene            complement(42069..42149)
                     /locus_tag="IRB70_001979"
     CDS             complement(42069..42149)
                     /locus_tag="IRB70_001979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631896.1"
                     /translation="MKDVDQNFDALYWHILQAYLILLFYD"
     gene            complement(42185..42610)
                     /locus_tag="IRB70_001980"
     CDS             complement(42185..42610)
                     /locus_tag="IRB70_001980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311733.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631897.1"
                     /translation="MDIEFSQIHEMVYMHDIVNSDSKKKPRIPLKKFLNAEKVLTQTT
                     SWVLNSRYVNVNSVSKVNVKSKVKNSYISRSVNDEFSLTDDEINSFKETLVLSSIDSL
                     SKLVLNNPLSVLFTSTVRRNNNRAKMNVEFDSWICTRCC"
BASE COUNT        10999 a        11318 c        10221 g        10421 t
ORIGIN      
        1 agcgtcgccc catcggcaaa atacgcttta attcccgcaa gaatagactc cgcaacttcc
       61 tgctggaaag tcgccgtttt cagtttacgc tcttcctcaa cgttactgat aaacgccgtt
      121 tcgaccagaa tggagggaat atctggtgcc tttagtacgg caaacccagc ctgttcaact
      181 tgatttttat gcagcttgtt gattttaccg agcttattca gcaccgcttt accaaactta
      241 aggctgtcgg caatggtcag cgactgcacc atatcgaaca tagtgtggtc gacatagcgg
      301 tcaccgcttt tgcttacgcc accaatcaag tccgaggcgt tctgggtttg tgccagatat
      361 tttgccgcag tactggttgc acctttggtt gagagcgcaa acacagagga accgctcggc
      421 tgacgactgg taaaggcgtc ggcatggata gagacaaaca ggtcagcacg ctgtttctgg
      481 gcttttgcta cgcgcacttg caacggaatg aagatgtctt cattgcgcgt catgtacacc
      541 ttcatattgc cctctttctc gatcagagag cgcagacggc gagctatttg caataccacg
      601 tctttttcgc gcgttttgta tttccccacc gcaccggagt cttcgccacc gtggccaggg
      661 tcaagcataa tgacaatcgg acgatcccgc ccagctttac ccggttgtgg accactttgt
      721 gctggcggca cctgcttttc gaggtcgcct ttgttgtaat cctccagcag cgccagcagc
      781 gggtcctgca tgtcctgagc attggcagga tagagatcca tcaccagacg ctctttaaac
      841 ccggcgaccg gcgcaagggc aaacagctgc ggttttacgt tttgctttaa ttcaaaaacc
      901 atgcgtacgg tttgcgggtc aaattgcccg acgcgcgccg acttgatgaa cgggtcgtct
      961 gcacgaattt gtgccgccat ccccttgagt accgagttca ggtttacatc ttcgatatcc
     1021 accaccacgc gttccgggtt actcaacgcg aactgcttat atttcagctg acgatttgat
     1081 tctaccgtca cgcgggtgta gctggacgca ggccagacgc gcaccgccac gacctggctg
     1141 accgcagcca gactgacctg acttacgctc aatagccaca tggcacccgc gccttgcagt
     1201 aaacgacgac ggctgattgc agtgttggat cctgacatgc ctctcccgag caaaagaaat
     1261 ctaagctgtg taacaagtaa acgactaatt tgaccgaaaa ctttagcgaa agacgcataa
     1321 tctgtcatct ataaaacggt aaacattctt tttatattca cggtattact gataaaaaac
     1381 tcgctcccgc ataaaattta cacttgcacc ctgcgaaaaa acagaataaa aatacaataa
     1441 tttcgaataa tcatgcaaag aggtgtgccg tggtaaagga acgtaaaacc gagctggtcg
     1501 agggattccg ccattcggtt ccctatatca atacccaccg gggaaaaacg tttgtcatca
     1561 tgctcggcgg tgaagccatt gagcatgaga atttctccag tatcgttaat gatatcgggt
     1621 tgttgcacag cctcggcatc cgtctggtgg tggtctatgg cgcacgtccg cagatcgacg
     1681 caaatctggc tgcacatcac cacgaaccgc tgtatcacaa gaatatacgt gtgaccgacg
     1741 cccaaacgct ggaactggtg aagcaggctg cgggaacatt gcaactggat attactgctc
     1801 gcctgtcgat gagtctcaat aacacaccgc tgcagggcgc gcatatcaac gtcgtcagtg
     1861 gtaattttat tattgcccag ccgctgggcg tcgatgacgg cgtggattac tgtcatagcg
     1921 ggcgtatccg gcggattgat gaagacgcga tccatcgtca actggacagc ggtgcaatag
     1981 tgctaatggg gccggtcgct gtttcggtca ctggcgagag ctttaatctg acctcggaag
     2041 agattgccac tcaactggcc atcaaactga aagctgaaaa aatgattggt ttttgctctt
     2101 cccagggcgt cactaatgac gacggtgata ttgtctccga acttttccct aacgaagcgc
     2161 aagcacgggt agaagcccag gaagagaaag gcgattacaa ctccggtacg gtgcgctttt
     2221 tgcgtggcgc agtgaaagcc tgccgcagcg gcgtgcgtcg ctgtcattta atcagttatc
     2281 aggaagatgg cgcgctgttg caagagttgt tctcacgcga cggtatcggt acgcagattg
     2341 tgatggaaag cgccgagcag attcgtcgcg caacaatcaa cgatattggc ggtattctgg
     2401 agttgattcg cccgctggag caacaaggta ttctggtacg ccgttctcgc gagcagctgg
     2461 agatggaaat cgacaaattc accattattc agcgcgataa cacgactatt gcctgcgccg
     2521 cgctctatcc gttcccggaa gagaagattg gggaaatggc ctgtgtggca gttcacccgg
     2581 attaccgcag ttcatcacgg ggcgaggttc tgctggaacg cattgccgct caggcgaagc
     2641 agagcggctt aagcaaattg tttgtgctga ccacgcgcag tattcactgg ttccaggaac
     2701 gtggatttac cccagtggat attgatttac tgcccgagag caaaaagcag ttgtacaact
     2761 accagcgtaa atccaaagtg ttgatggcgg atttggggta agcgatggaa atcgccggat
     2821 gcgacatgca taacattcac aggcatgata agacccacat gcgtcgcatc cggcaattac
     2881 gtttattccc gcgaactaaa caacgccgcc agaccactgc gccgctcggt gcgcgtggca
     2941 attgccgcac ttaaaatgcg ctcatcggca tacagcgaca gacggcgacg cgcgcgggtc
     3001 actgcggtgt aaaccagctc tcgcgttact accggcgtgc gttgactcgg taaaatcaac
     3061 gccgcatggt cgaactccga tccctgcgat ttatgtaccg tcatcgccca cgtcgtttcg
     3121 tgctctggca ggcgactcgg ttgcacagac ttaatattgc cgtccggcat cgcaaaccag
     3181 acgcgcgtcc cctgcccacg atccagcgca ataccgatat cgccattaaa caacccaagc
     3241 gcgctgtcat tacgggcaat catcaccggt cggccttcgt accaacgaga gtgcggatga
     3301 cgatgaattt tgcgcttctg ttgcataaac tgctcaattc gctcattcag tccagccacg
     3361 ccaaacggcc cttcccgcag ggcgcacaaa agctggtact cattgaacgc ctgaatgatt
     3421 aaatccggct cggcacgcgc ttgcagcaga tccagataac gtccgtaacc cgcaagagct
     3481 tcctcaagca tcgcaatata atcttcgccg ctctgtaaaa gccgtttttc gatatcagaa
     3541 aaatcctgct gaaaaacggt tttcactgcc gttttatcac cacggttgat cgccgcagct
     3601 aactgaccaa tgccagaatc gctgccgaaa cgatagcttt tttgcaacag gcagagactg
     3661 tcgcgcaaag atgccgcttc tgtgccagtt cctgccggaa cgtgagttcc cgtcaggcgg
     3721 cttagctgcc cggcacgctc ggcggtaaag ccggcattgg cataagcaca aatatcgccc
     3781 agcacagccc cagcctcaac cgaggccagt tgatcacgat cgccgagaaa gatcactcgc
     3841 gcatgatcgg gcaaggcgtc tatcagtctc gacatcatcg gcagatcgat cattgacgct
     3901 tcatctacca ccagcacatc aagatgcagc gggttaccgg catgatggcg taaacgctgg
     3961 ctacctggct gcgcgcccag caatcggtgc aaagtactgg catcttccgg aatgcgtttc
     4021 ttttgttcat cggtcagcgg taactggcgc aaagccttgc cgagagattc ggttaagcgc
     4081 gcggcagctt tacccgttgg tgcagccaga cggatacggc agcgttcgcc gtcggccatt
     4141 tgaattaacg ctgccagcaa cttcgctacg gtggtcgttt taccggtgcc agggccgccg
     4201 gaaatcactg agatccgccg cgtcagcgcc actgccgccg caactttttg ccagttaatt
     4261 tcatcgctta ctggaaaaag tttgtccagg gtttgcgcca gtagtgcttc atcaacctca
     4321 atggcatgat tcacttcgtt gaaaaagcgt gccactgtgc gctcgttaca ccacatgcga
     4381 ttcaaataaa gacgatcgcc acagaggatc atcggcgttg gttcatctcc ccggctgacc
     4441 gcttgtgaag ccagcaagca ttcttcccaa ttttgtagct caccgatttc actgacacag
     4501 gtcgccaaca gcggatgcga tgcctcgtta ttttccagtc gtgaaagcgg caaacaaacg
     4561 tgtccctctc cggcatcatg acttaacagt gccgccgcga gggtgacggc aggatgttca
     4621 tctcccgcca cggtcagggc aaactgcacg tccagcgggc gtagctgttt gtgctccaca
     4681 gcttccagta attgcttttg caatttcatt acgcctcctc cagggtcata ccggcaaaca
     4741 tctcatccat caggtcaatc aacccggcgt tgggtcgggt cgcgtagatc ccttgttgcg
     4801 gatgttcttt atcaacgcca cgcaggaaca gataaataac gccgccaaag tggcgctcat
     4861 agtcgtaatc agcaatgcga tggcgcagat aacggtgcag cgccagggta taaagctgat
     4921 attgcagatc atagcggtgc gcctgcattg ccgctgccat agcctgttgg gtgtaagccg
     4981 aactgtcttc acccagccag ttggatttat agtcgagcag gtaataacgc ccttcgtggc
     5041 ggaacaccag gtcgataaag ccttttaaca tgccacgtac ctgcatgaac tccagcggcg
     5101 ggcagccagc ggatagcggg tcaaactggc gaattagtgc atcaagctga ctggcgataa
     5161 gcggttcact aatcggcagg taaaactcca tctccacctg tttatcgcga tcggaaagct
     5221 gattcaggct aacacccgtt tcattgagag gtgcctggag gacagccgtg atccactcag
     5281 tcaacaccgg ttcccactgc ggttcaaagc cgccgagctc cagtttttcc tgtacccagt
     5341 tcgggtcaac cggctgggta aaatcgaggt cttcaaacaa actgtgcaag aatgtccccg
     5401 gtgacgcacc gcgcgggaac tgatgcggtg ttaacgtcgg ttcttcaacg acgctgacca
     5461 cgcctgcggc atcaacatcc aaccgtggca tcagatcctg agcgataccg tgaccacgct
     5521 gctgcaaacc ggagtagctg gtgacacgcc agttatcgcc gggcaatcgt tgtagcgtcc
     5581 tcgcattcag ttctgcagtt aatgcatcat taacctgcca gggctggtta tcaccagttt
     5641 gtgccgtttg ccaggcaata tcatcatcgc ataacgcttc aatacaggtg cgaagccctg
     5701 ccgcatcttg cggttcccct ttttgcagca aacgcccgag cgcactttgg tggacgtcgg
     5761 tatcaccttt tttatcgcca cgacggcgca ccagcggtgc aacgccgaga ctgcaatgcc
     5821 aaaccgaacg cgtcagcgcc acgtaaagca aacgcagatc ttccgccaga cgttcggcct
     5881 ccgcgaggtc gacgctttct ggcgcagcat taagatccag aacagcctca aacgagtggc
     5941 gatcgtgata aaacgcctga tcctggacgc ggaaattggt gataaacggc agccagacca
     6001 atggatattc cagccctttc gatttgtgga tcgtgacaat ctgcacgaga tgtttatcac
     6061 tttcgagacg catttgttgg ctggaggcat tactgtctgg ctcgaggata tgttgcgata
     6121 accagcgtac cagcgcatgt tcactttcca gctgcgtgcc ggcttcttgt agcaattcgc
     6181 tgatatgcaa gatatcggta agacgccgct caccgcctgc tgttgccagc aagttttctg
     6241 caatgttacg cgccgacatc agcgcccgca gcatcggcat aacgccacgt ttgcgccaga
     6301 tttgccgata accatcgaac tcttcgacta ccgcatccca cgcatgttcg tcattattca
     6361 gcgtttcaat atccagcgca ttcagcccca tcattgacgt tgccagcgca ctgcgcaggg
     6421 tgttctcacg ttcgggtgtc atcaccgcct gcaacagcca aagcatctcc tgtgcttcca
     6481 gagtttcaaa aacactgtcg cggttcgaaa ggtaaacgga agggatttcc agcagcgtta
     6541 aggcatcgcg cacctgagcg gcctcctggc ggctgcgcac cagcacactg atgtccgaag
     6601 cacgcaccgg acgcgcgtcg tcgccgttca tcagcaacgc ttcgccccgc tgtccggctt
     6661 gtagccagtc gcggatttgc gcagcacata cctgcgccat ggtactttga tagtcgccaa
     6721 cgccgcagct ttcgccttcc atcagccaca ttttcatcgc aggctgcgtt tcacctttaa
     6781 acacaaaacg taacgcctga tttttcccgg ctgatttcac tggaataaaa ggaatttcgc
     6841 gaaacatgaa cgcgtcatca gtctgactga aaagtttgtt aacgctgttc accattcccg
     6901 gtgcggaacg ccagttggtg tctaaggtgt agtgggcgtg aacttcgcta cgcgccttca
     6961 tataagtgaa gatatccgca ccccggaatg cataaatggc ctgtttcggg tcgccaatca
     7021 gcaacaatgc ggtttccggc tgatggtgcc agatacggcg aaaaattcgg tactgctggg
     7081 ggtcggtatc ctgaaattca tcgatcattg ccaccgggaa tcgcgtacgg atcgccgctg
     7141 ccaatacctc gccgctttca ctacgcagcg cggaatcgag ccgacttaac atgtcatcaa
     7201 aacccaattc gccacggcgg cgtttttcac gcgctactgt ttcgcggatc tcagctaatg
     7261 cgcgagtgat caccagatcg cggatcgaca atggttctgc aagcagttga tcgatcgcct
     7321 caaacagtgg atgtcgcggg gtttcccccc cggctttcgt gcgatcttct aagaaacgct
     7381 gagagaattt ttccagcgac tctggcaact gatagctgtt ggtctcttct tctgcccagg
     7441 cgctgatctt gtcgatccat ttagcctgat tgctacggtt aaacttgcgt cgatcaatac
     7501 cagaagattc gatcagcgca tccagttcac ccaccgcgtc gcgccactgc tgttttaccg
     7561 tatcaatacg cgccacaatt tgcgcgtggc gggaagccag cgtttcatca tcgggcggcg
     7621 gcgctttgat aaccggcgct tcgccttgca gataacgatt aatatcgcgc agtaacgcct
     7681 gcggcccttt ccaggtttca aagacgacct gggcaatttc acgcggcagc gggtagcagt
     7741 ggcgacgcca gaaatcggcg caggcctggt aacgtagcag agactcatct tcaatcagct
     7801 gctgctcaaa cagcatgccg gattcaaagg cattcaggtt gagcatgcgc tggcaaaaac
     7861 cgtgaatagt aaagactgcc gcttcatcca tctgccgttc ggctaacaac aaccactgcg
     7921 cggcttgcgc tttatcgtcg atctcttcca gcaggcgttt gtacagtgga ttgtcggtgg
     7981 tttcacgcag acaggcgatg cgcaactcgt ggatattgct acggatacga ccgcgcaatt
     8041 ctgccgtggc agcctcggta aaggtgacca ccagcagttc ttcaacggtc agcgggcggg
     8101 gaaaggcggc agaaccgcct agtccaagta acaggcgcaa atagagcgcc gcaatcgtaa
     8161 aggttttgcc tgtgccggca gaggcttcaa tcaggcgctc gccctgtaag ggcaagcgca
     8221 aaggatctag tgtctcggcg acatcactca ttcttttcac tcatcagggg cattgtttgc
     8281 tgcaacgcgc tgacgttctc ccacactttc cagccttcag gatgcacata ttcggctttc
     8341 ccgttctggc tgccggaaat ctgcgacaga atagccatac cttgcggctc gaccaccgcc
     8401 tgatggaaga aatcagcaag tttttgcggc gtcagcagtt ttatctgggc cacgatttta
     8461 tcacgcgaat cgaagcgcat attgccgcga tcgaaatctt tacttaactt cgatgcttct
     8521 tcgccgagcg tttgcggtgc ctgcagcatc tgggtaatta ccgcctgctg gatttgcgca
     8581 aactcttctg gcttcatcgc ccgcagtttc gcttctgcgg tcgggaaaaa cgccttgtaa
     8641 cgctcccaca agaatgaagg ctgtttatca ttgctttgca acaggaagcc catgccccac
     8701 tgacgcccca cgctcattgg aaacgcaaac acggcatagc ccaactgttc ttcggtacgc
     8761 aactgattgt agaaccacgg ctgtacgatc tgccccaaca gagaactata cgctgaactg
     8821 gtgtattcat cgtagccagt cggtacaaat accgctgcca gtgcggagtc ggtgctgtta
     8881 ccggcttttt caaagatgac ggattgtttt ttatcgacca cgacatcttt gttacgacac
     8941 cactccgaac catcagcgcc caactgtttt tgcacatcgc gtgccagcgt tgttgcctgg
     9001 gcctcggtca tgttgccgat aaccataaac tctggtcgag cccctgattt taaggcgtcg
     9061 cgataggcca gaacttcttt caaagtaatg gagggcaaaa ttttgcgccg ttcatctcgc
     9121 gagaagtatg gtacttgcga gagcatctgc gcgggcataa tcgcctgctc gaacgctttg
     9181 cccttttctg cagaatccat catctggtta taccaggact tcgcctgctc aagctgatct
     9241 tccgtagcgg tatagctaaa gtacccctcg agcaatgcct ggaacagctg cggcaggcgc
     9301 tgggtgtaac cattggcatt aaccataagg ccgttgttag cattggtgga aaaacttatg
     9361 ccaccaaccg acgcctggtt gcttaactga tcaagcgcca gccctgcgag ataatcattg
     9421 agcgcaaaca tcacctgatt gcgggcgcta tccatggctt ttggattacg caaaatcagg
     9481 ctgacatcag ctttgggttc gctggaaaaa taacggcttg gcgcatacac cacacgcaga
     9541 ttcgactcat caacaatcag ctctggatgg tcatatttct tctctgactt aatcagcgag
     9601 aaatcgtcag gaatataggg gttaagctct ggcaaagaga gcgcaatgtc ggcggctttt
     9661 ttctgccagt cagcgaaagt ttgtgcgcta attttatcga cctgatacgg cgcatcgaca
     9721 aagtaagccg ttttgttgtg cggctctttc gggctgatat accagatacg cgcattctgc
     9781 ggcgtcatca tcgccaggcg ttcttttact gctttagcgt cgtaccgatc ggcaatattg
     9841 actgcatcca gcgtatgctc aacaggaacg cgaatcatgg tatctgccag ccattcgacg
     9901 taatccatat cacgggtgat tgacggataa cggaagtcga tatccagcac attcgccagt
     9961 tcatcgaagt attgtttatc aatccctttt tcgcgtaaca gattgaggta gctaaaaatg
    10021 gccgccacaa cctgatcgcg attcgccaga cctttatcgg ttaaagacgc agagatcgct
    10081 aatacgccgc tgttgccgtt gacgatagga tcggaattgg cgctaatacc ctcaactaat
    10141 ccctgctttt gcagccagtc agaaagtgta cctgggctgc gattaccaat cagataggta
    10201 atcaattcat ccgttttact acggaacttc gctgaattgt tatcgatgcg aaactcaacg
    10261 cgcagaactt tacgcggcaa cgccgggacg taatgaatga taatgccctt ttgcgcgtcg
    10321 gtgactaccg gcacggtgat ttccggtttt ttgctctctt tgttcggcac gcgaccaaag
    10381 gtgtccgccg ccattttcgc caactccggc aacggtttat tgctgtaaat aaccgccttc
    10441 atcagattgg cggaatagta cttctcgtgg aaatctttca gcgcctgctg taccggatta
    10501 cctggtttgt cgcttaaagt ttcgaggtta ccaccagaaa actttgaacc ggggtgtgcc
    10561 gggttaatgg tttctgcgct gacctgtgcc atgcgcatcc cgtcacgcgt acgcgccatg
    10621 gttaattcgg cattcactgc attacgttca cgttcggcgt atttcttgtc gagcaagggt
    10681 tctgcaatag catcggccag gcggtctacc gcaccgggta aggcatcgtt ctcaacttcc
    10741 agatagaaag ccgtgcgata cggtgccgtg ctggcattgt gactgccacc gtgcattttg
    10801 agatattcgg ccagactgtc agcctgcggg tactttttcg accccatcag actcatgtgt
    10861 tcaaggtaat gcgccagccc ctgatacgcc tcgggatctt ccagcgaccc aacgggcacc
    10921 accagcgccg agagcgattt aaccgcctgc ggatcagaaa ccagcaagac caccataccg
    10981 ttatccagac gtatagcctg atactggcgg ttatctttat cacttttacg gatggtttcc
    11041 tgaatcggct gccatcccgt ttctgcctga cttaagggtg cccaaagggc aacaaacaac
    11101 aataatgctt tgaaccagat gctgcggggc attcacggac ctcataatca actttatttt
    11161 ctggccagat tcaacaggtt aacgcaaatc atctgccaga atttaatctt gtgctgcacg
    11221 agtcagccta tgtctatata tccatcagtc cgtgactggt gcgcatcata aagcaagcag
    11281 atatattgcg caatttttat acagcactca tgactgatta aagcgaaaca gcggtaacag
    11341 gaaacgttgc gactgttcaa cgatggcctc cattgtctct ggtgttaatt gccgccagag
    11401 ccgttgatac cagatatcat caccttcgcc acgcaccatc atgttgcctt cgtaagcctg
    11461 aaggaatttc gttcgggctt tttgcaacgt ggaatcgtca tccagcatgg catcgttttg
    11521 cgcgtcataa caggttttta gccacgcgcc gccactttca ggtaacacca gcaatggcgc
    11581 ggacattcct tcacgatacc cctcaatcag ttgtgagagg taatgcaaag cctgttcggc
    11641 tgcaagcggc ggaaaacgcc actcgccgtc tttgcgtaga aaaaggcgac tttcaccatt
    11701 accaccgctg gcacagtaga caaggtgttc cagccaaagt tgcattccct gcgccacact
    11761 taataaagag ggacgccagc gcaacaggcc atccggctgc acctgcggca accagccagt
    11821 tatctgcaca ccgttgcagg cgagatcaat ctccatactc tgccctggct ggcgacaggc
    11881 aatgactctg tcggcaagtt gctgcatctc ctgacactgc gtttcccaga aaatttcacc
    11941 aaaggcacca tacggcaaat cacctgccgc ccggaatcgg cggaacaagc gttcggcatc
    12001 atcctgctca accagtgcat ttaataactg ctggttgatt tgataacgac taagcccttc
    12061 aagaataaaa ggttcggtgt cgggaatttc gctgtcttcg gtacggaagt tcacctgcaa
    12121 acgcatctgg aaaaacgccc gcaccggatg cgcccagaat cgttgtagcg tctccagcgg
    12181 cacagtttcc ggcaaggtaa acggcagcgg ctgaacaaat tcagaatgtg ctttaccagc
    12241 ctggctggcc gcaggtagcc actcgcgcgc atagctttgt cgttcgcctg gctggtagtt
    12301 ttgtggatca aacggcattc gggtatggag gcaagtaaga tgcgctttta cccttgcctc
    12361 gctttcatca cagttgagcg cttcatctcc cggtagataa tggctttgcc cgatgtagtc
    12421 gatcagttcc tgcaccagta ccgacgggaa acgttcactg ttatcctgaa tggaacgccc
    12481 gatatagctg atatagagtt tttgctgcgc ggaaattaac gcttccagga acagatagcg
    12541 gtcgtcatcg cgacggctac ggtcgccacg cttcggtttc tggctcatca ggtcaaagcc
    12601 caatggcgca agctggcgtg gataaacgcc atcgttcatt cccagcaggc aaaccacttt
    12661 gaatgggatg gaacgcattg gcatcagagt acaaatgtta accggtccgg cgagaaaacg
    12721 ctggctgata cgttcctgat ccaggcgctg tgccagttca tcacgcaata gtgacagcgg
    12781 caccgcgtcg ccatactgcg cacctaaacc ttcggcgata atcgcctgcc attgttgttc
    12841 gatcagcgtc atcgccgctt cggtttccgc atccggcagg aagaaggcgt tgagcatatc
    12901 gcgacaaacc ggcaaccact cttccagcgg acgctcctgc gccagcccgc gacgccagat
    12961 gtttagctgc attagcagtg aagccagatg ccccaccagt tctgcaatta agccgctcga
    13021 ttcatcataa ggtagaaccg attgccactc gccctgcgcg ctctccatcg cgtagcccag
    13081 caacatgcgc gtcaggccaa accgccaggt gtgttgaccg gtagcgggga gttccagctc
    13141 gcgaacgttg tcgtcatcta tcccccaacg aattccggac tcgttgaccc actggcgtaa
    13201 ataacgcagc ccttcttcgg tgatgtcaaa ccgcgccgcc agcaccggca catccagtaa
    13261 tgccagaacg tcctccgaca caaagcggct gtctggcaac gataacaggc tgataaacgc
    13321 ttcaagtaca ggatgcgact gccgcgcccg acggtcggaa atggcgtaag gtaggtaacg
    13381 atccgcaggt gcgctaccaa acacagcctg aataaacgga ctgtagctgt cgatgtcggc
    13441 caccatcaca atgatgtcgc gcggagtaag tgtcggatct tcttccaaca tcgccagcag
    13501 gcgatcgtgt aaaacttcaa cttcacgctg tgggctatgg caaacgtgga aggtgatact
    13561 gctatccagt ggatcaagcg ggcgtttgtt atcgctacgg gaaaactctt cgatgttcac
    13621 acccgcaacg gcgcggtttt ccagttccag aatgtcagac tgaatgttat gcagcaggtt
    13681 atctggcgtc acatcgacaa aagcgtccag ctcctggctg ctctccagat cagaaaggag
    13741 ataaatgtag tcgcgtccaa gcttgcccca tgaggccagc agcgggttgc cgacatcctg
    13801 ttcaccatcg ctgttaaaga gctgcccggc attttcgctg tcgcgaaata gcggtaattc
    13861 gcgatcttca aaactgtgtc ggcgctggcg agtcagcagt ttcgccagat aagcaggatc
    13921 tttaatgtcg ccccagtaat aacggcaggg gttggtaaac aggagatgga tttcaatatg
    13981 tttacccagc gcctgtagcg cctggagata aacaggcggt aacgcggaaa taccgcatat
    14041 aaagacgcgc gaaggtagcc ccggcgggca ggtcgtcgcg gactccagcg tttcgataaa
    14101 gcgctgatag agattggcgc ggtgccagcg cggttgcccg agttgatggg tatattccac
    14161 caacgccttc cacaacggcg cttgccaggc ctgtgcttct cccagccctt caaccaaatg
    14221 tcctgtttcc cactgtgcca gccagtccgg acgatagacc agatactggt caaacaggtc
    14281 cgccgctttt gaagaaagct ggaacagttt tcgcttgtcg ctatcgtcag tcagataatg
    14341 ccgcaacagg gtaaagtctt cgcgatccag caattgcggc aacagagtca tcagtttcca
    14401 gctcatgctc tgtttgttaa aggcgctctc tttggggatc tccgataaca cccggacgaa
    14461 catatcccag ataaagctcg caggcagcgg aaaatcaatg tttgccgcaa taccaaactt
    14521 ttgcgacagg gtcatttgca gccactgcgc cataccggta ctttgcacca gaatcatctc
    14581 tggttcgaaa ggatcgtcca gccgttcgcg ttcgacaata aactccatca acgcttccag
    14641 cacgtccaga cgattggaat ggtagaccct taacatagcg gctcctgact actgacgatt
    14701 cgggcaatgc aggcgggtca tctcgccttc tctgcccccg ggtgaaacta gcgtaacgct
    14761 gatgctgaca catcccgcct gcgatgtctg cattcggttg acctgccagt tggcaggtgg
    14821 cgaaatcgca cgcagttgcg tttgctgcca gccatgccgc cagagctgtt ggtactggtt
    14881 tctgctggca agactgttca ttaatgttcg ctggaaaccc gataacgcag tgacaatcat
    14941 caccatcaac accatcgcca acattacctc cggcaggcta aagccttgtt gattcttcag
    15001 ggaagctgac ataacgccct ctctttcagc ggacaaaaat cgctccagcc gcgtggcgaa
    15061 aaaacaatgt ttccatcgat gacttcgcct gttcgccaca acgaaacgcc ttcataaccg
    15121 gcaatcaata aagcctcatt atctgccaat aaacgcagac aaacccgggc accggtggca
    15181 gcgtacagta agcactgaac tgctggctgc gtctgccagg agtgcatttt tccccactcc
    15241 agcgccgact gaacgatggc atggcggcgc aatgactgac tttccatgct cacgcgagag
    15301 gcaaaactgc gatcctgttg gctcattcct tgtaatagca agctacccaa aatcagcagc
    15361 atcaggacca gagccagtga cgagacaccc ttttcgcggt tcacaggttg gatcctgtca
    15421 cgctatagct ggcatccacc acggtttgcg gatcagcctt gctggcagcg tgcatattaa
    15481 ccgtcaacac cggcgagaag ccgctgacat cctgacgtac gacctgaaaa gtgtcgataa
    15541 tgatggcatc cggattagtg actttatccc agcccttacc ttcacaggat gtcgcaccgc
    15601 gtagcgtttc cagcacatgc tccttcagac gaaatccaat ctggtcggac tcttttaccg
    15661 gttcgcgatc ccagataccg ttactgttcg catcccactg cacaatgaca cagtcaccct
    15721 gtccgacaat ttccagccct tcgccggtac agctgccatg acaataaccc gccctctgga
    15781 gatgcttcgc aacggtaaat acccgcagcc agatttcatc ttccagcgcc agcttacggg
    15841 tgctcgttaa actgtcacgc tgtaacgcag gcagaaagcg tgcagccccc agcaacaata
    15901 cgctactgat cgccatagca atcaacactt ccagcagaga aaaaccttgc tcttttacag
    15961 gcatccttct gtttctcctt gctgacaaag ccggagtctt ccccacggcg aaaccaccag
    16021 ccaccactcg cccgttgagt ttttgaagcg aatatgcccg gcccatgcgg tattgcgcag
    16081 gccaaagaaa gcaagcgaag gtgtcagatc gctcatttcg acttcgggcc agcgtggcac
    16141 aaagaccaat ggtgaactgc catgacaggt attggcccca gcagcggaac tcacaaggca
    16201 ccataacgtc ccctccctga taacactgat actgtggtcg cggttatgcc agttggcatc
    16261 ttcacgtaaa tagagcaaat agtcccgcgc ctggctggcg gtttgccaaa gccgttgcga
    16321 ctgctgccaa tattgccagc catagagccc acttgcgctt agcatgacca gaatcagcat
    16381 cgcgaccagc gtttcaatca gcgtataacc acgttgtgtt ttcatgccgg cagtatggag
    16441 cgaggagaaa aaaagacgag ggccagtttc tatttcttcg gcgcatcttc cggactattt
    16501 acgccgttgc aggacattgc aaaattgcgg gaaggcgtct cgaagaattt aacggagggt
    16561 aaaaaaaacc gacgcacact ggcgtcggct ctggcaggat gtttcgtaat tagatagcca
    16621 ccggcgcttt aatgcccgga tgcggatcgt agccttcaat ctcaaagtct tcgaaacggt
    16681 agtcgaagat ggattcgggt ttacgtttga taatcaactt cggcagcgga cgcggttcgc
    16741 ggcttaattg cagatgagtt tgatccatat gattgctgta caggtgcgta tcgccaccgg
    16801 tccagacaaa atcacccact tccagatcgc actgctgcgc catcatatgc accagtaacg
    16861 cgtagctggc aatgttgaac ggcaggccga ggaagacgtc acaggagcgc tgataaagct
    16921 ggcaagagag tttgccgtct gccacataga actggaagaa tgcatggcac ggtgccagcg
    16981 ccattttatc cagttcgcct acgttccacg ctgaaacaat aatgcggcgc gaatccgggt
    17041 cgtttttcag ctggttcagt accgtagtga tctggtcaat atgacgacca tctggcgttg
    17101 gccaggcgcg ccactgttta ccatacactg gcccgaggtc gccgttttca tcggcccatt
    17161 cgtcccagat ggtgacattg ttttcgtgta gataagcaat gttagtgtcg ccctgcagaa
    17221 accacagcag ttcatggatg atggaacgca ggtggcaacg tttagttgtc accagcggga
    17281 atccatcctg caggttaaaa cgcatctgat gaccaaaaat ggaaagcgtt ccggttccgg
    17341 tacggtcgtt tttctgtgtg ccttcgtcga gcactttttg catcagttct aaatactgtt
    17401 tcatggttcc tcaggaaacg tgttgctgtg ggctgcgacg atatgcccag accatcatga
    17461 tcacacccgc gacaatcatc gggatggaaa gaatttgccc catgctaatg tactgcaccc
    17521 aggcaccagt aaactgcgcg tcgggctggc ggaaaaactc aacaatgatg cgaaacgcgc
    17581 cgtaaccaat caggaacaaa cctgagacag ctcccattgg gcgcggttta cgaatataca
    17641 ggttgaggat aataaacagc accacacctt ccagcagcag ctcgtaaagc tgtgatgggt
    17701 ggcgcggcag cacaccgtaa gtgtcgaaaa tggattgcca ctgcgggttg gtttgcagca
    17761 gcaaaatatc ttctgtacgg gagccaggga acagcatggc aaacgggaag ttcgggtcaa
    17821 cgcggcccca caattcaccg ttaataaagt tgcccagacg cccggcacca agaccaaacg
    17881 gaatgagtgg tgcgataaaa tcagaaacct ggaagaagga acgtttagta cgacgggcga
    17941 agataatcat caccacgata acgccaatca ggccgccgtg gaaggacatg ccgccgtccc
    18001 agacacggaa cagatacagc ggatcggcca taaactgcgg gaaattgtag aacagaacat
    18061 aaccaatacg tccaccgagg aagacgccga ggaagcccgc atagagtaag ttttcaactt
    18121 catttttggt ccagccgctg cccggacgat tcgcccgacg tgttgccagc cacattgcaa
    18181 aaatgaaacc caccagatac atcaggccgt accagtgaag cgccacgggt cctattgaga
    18241 aaatgaccgg atcaaactcc ggaaaatgca gatagctact ggtcatctgt caccacaagt
    18301 tcttgttatt tcgctgaaag agaacagcga ttgaaatgcg cgccgcaggt ttcaggcgct
    18361 ccaaaggtgc gaataatagc acaaggggac caggctggtt gccggatacc gttaaaagat
    18421 atgtatatga tccgcgctat aaccctccgc gaatcagccc gcccatgccg cgacgctcca
    18481 taaaggctgc aacctgatgg cgaacttcgg tcgccagttg cgcttccaga ctacgctgcg
    18541 caagattttc tgcttcagca aaatcaatgc gccgcagcag gtattttacg cgcgctacag
    18601 aacgtccgtt catagacaga tggcgatacc caagcccaat gaggattgcc acgcacatgg
    18661 gatcgcccgc catttcaccg cacaaacgga gatcgattcc atgtatttcc gcttcccggg
    18721 cgatcatcgc cagagctcgt aacattgcag gatgaagact gtcataaatg ttcgccaccc
    18781 gggtattgtt gcgatcaacg gccaggatgt attgcgtcag atcgttggtg ccaacagaga
    18841 tgaaatcgac ccgctttgcc agatgcggca gcataaatac cattgacggc acttccagca
    18901 tgatgccgat acgtggtttg ggaatttcgt aaccgatcat ctcctcgact tcacgtccgg
    18961 cacgttcaat caggcggcgt gcttcgtcaa cttcatcgag gcttgtgacc atcggcaaca
    19021 gaatattcag gttgcccgta gcggcattag cacgcagcat cgcacgcacc tggatcaaga
    19081 agatctccgg ctgatcgagc gtaatgcgaa tcccacgcca acccaggcat ggattctctt
    19141 cgctgatcgg catgtaaggc agctgcttat ctgctccgac atccagcgta cgcaaggtga
    19201 cgggtttatc attaaacatt tgcagcatcc cctgatactg cgccacctgt tcttcttccg
    19261 acggaaaacc actttgcagc atgaatggga tttcagtgcg ataaagtcct atgccatcaa
    19321 tacggctgcc cagtttttct tcatgttccg ggcttaaacc ggcattgagc atgactttaa
    19381 tgcgctcgcc gctttttaac tgggcgggta aattgacgtc atcttccgcc agacggctaa
    19441 gctcaatctc ttcactaatt agccgctgat attcttgcag cagtaccggc tccggatcga
    19501 ccagcaattc accgcgataa ccatcgacga tcagcgtccg acgatgcagc accgaaggct
    19561 gaatatccgc gcccatcacg gtagggatcc ccagcgcacg taccatgatc gcagcatggg
    19621 agttggcagc gccatcgcgc acgacaacac cgactaagcg atcctggggc agctcagcaa
    19681 gcgttgtcgc tgacagttca tctgccacca gaatgaaacg ttccggccag gcgttcggcc
    19741 cttgattagc gtcatcaaga tgaaacagca atcgctggcc cagcgcacgt aaatcgccag
    19801 cccgctcttt gagatagtta tcgcttagcg cggcaaactg ttcggcaaat ttttcaatga
    19861 ccgtttttac cgcccactct gccaccgagc ctttatcaac ctcggcaaac aattcgcgac
    19921 gcagccgggt atccgaaagc aggtgtgagt aaagatcgaa aatagccgcc gtttcttttt
    19981 gtgcaccggc agcaaagcgt ttgctataac ggcgaaactc gtttgccgct tcttccagcg
    20041 ccccggtcag tcgttcgcgt tccagagccg gatccagcgt tgatgcctga tacacctgtt
    20101 ccattaaagg taacgtggca tcctgccagc cttcggcaat cgccacacca ggtgctgccg
    20161 gtaatgcgcg gattcgcgtc tggcgatatt gcccaaacaa ggcagtcaac tgcgactgag
    20221 aaagaatagc tgccatctgg gtggcaagcg tcaccaggaa ggattcttca ctttcgtcat
    20281 actggcgcaa ctctcgttgc tgtaccacca gtacaccaag caactggcga cgttgaataa
    20341 ttggtacgcc taaaaatgcg cggaaacgtt cttcttttac ggaggggacg tatttgaagc
    20401 tggggtgctt ttgcgcatct gcaaggttta tcggttccgc cagcctgcca accaggccga
    20461 cgatcccttc atcaaacgcg agcgttacag tgcgaccgcg tggttttttc agcccccggg
    20521 tcgccatcag gtagtaacaa cgtcgatcat gatcggcaag gtaaaccgaa cagacctcgg
    20581 tatccatcgc aagacagatg tcggtaacca gaatatttaa cgcctcattc aggcgtggtg
    20641 cgctggctac cttttcgact atttcgcgca ggcgagtgag cataattggc gtgacttaac
    20701 ctcttttacg tcgataagca gatgcgtttt gtggttttgg cgtattttcc tgcagtgaca
    20761 tcaccacact cgcgaactct ttcattacct tacggtagac atcacgttta aatgacacca
    20821 cctgtctgac cggataccag taacttaccc atcgccagcc gtcaaactct ggtgtactgc
    20881 tggtttgcat attgatttct gcatcgccgc tcaccagctg caagagaaac catttttgtt
    20941 tttggccgat acaaaccggc ttcgtgtccc aacgcaccaa acgtttcggt aatttgtagc
    21001 gcaaccagtt acgcgttgaa gcaaggattc gaacgtcttt acggcttaat cctacttctt
    21061 caaacaattc acggtacatc gcctgctctg cggattctcc ggggttgatt ccgccttgcg
    21121 gaaattgcca ggagtgctga ccaaatcgcc gggcccacat tacctgcccc tggcgattac
    21181 aaatcacgat acctacgttt gggcggtagc catcgtcatc aatcaccgga ctacctcaaa
    21241 ataaagcttt atatacgaat gattgtttca tactccagga agacggtaaa ccactctctg
    21301 cagggcatta cacactaata acaattgaat aactcacagt tatgtgcaga gttataaaca
    21361 gaggaagggg tggatagccg tttttattca ccttttctgt ggatagagtt gtgaagaact
    21421 acggaattac tacgggaaaa cccggagcat tctgaataag cccgatatag acattttaaa
    21481 atattcatta tcagtcaatg cattacatgt aattttagta ataaaaaaga gtaattcgtg
    21541 acccaggtca cacctctcat ttacgggttg gcgaaagatc aaccaatgcc gtatttatcc
    21601 acagaatgtg ccactaagtt aagcactgaa ccactaaaaa ctggagtttc gtcgcacgtc
    21661 aaggctgtaa atggaaacag tagtggaggt ttttcacagt tatcccagct ttctgtggat
    21721 aacatggtgt aagatcctgt ttattttcag tgaccagatt tggaaaaccc attgcagtgt
    21781 tgcgcaactc gattaccggc aacctaaaaa gcaatataaa tcagaggatt gaacaacgcc
    21841 tgtggaaaaa gttacactgc gaatattcgg cacataattg ctgtttgttt tttaaccaag
    21901 gtatcgtgac atgtcccaac ctcgcccact gctctctcct cccgaaactg aagaacagtt
    21961 gttagcgcaa gcacagcaac tttctggtta tacattggga gaactggcgg cacttgccgg
    22021 gctggttacg ccagagaatt taaaacgcga taagggctgg attggcgtgt tactggagat
    22081 ctggctaggt gccagcgcag ggagtaaacc tgagcaagat tttgctgctc tgggcgtgga
    22141 acttaaaact atccctgtgg atagtcttgg tcgtccgctg gaaacaacat tcgtttgtgt
    22201 tgccccgtta acgggtaata gcggggtgac ctgggaaacc agccacgtgc gccacaagct
    22261 caaacgcgta ctgtggatac cggttgaagg cgagcgcagc atcccgctgg cgcagcgtcg
    22321 cgtaggatca ccgttactgt ggagcccgaa tgaagaggaa gaccgacagc tacgcgaaga
    22381 ctgggaagaa ttaatggata tgattgttct cggtcaggtt gagcggatta ccgctcgtca
    22441 cggggaatat ttacagatac gaccgaaagc agcgaatgcg aaagcgctta ccgaagccat
    22501 tggtgcccgg ggcgaacgga ttctgacgct gccacgcggc ttttatttga agaagaattt
    22561 caccagtgca ctactggccc atcattttct gatccagtag ccatcgcttt gacctgccgc
    22621 tttccgggca tataattacc gcttcatttt tttggcaggg ctttttagat gttatttgca
    22681 tggataaccg atcctaacgc ctggcttgcg ctcggtacgc tgacgctgct ggagatcgtt
    22741 cttgggatcg acaatattat ttttctttct ctggtggtgg caaagctccc cacagcacaa
    22801 cgtgctcatg cgcggcgtct ggggttggcg ggagccatgg ttatgcgtct ggcgctgctg
    22861 gcatcaatcg cctgggttac gcgcctgaca aatccgcttt ttacaatatt cagccaggaa
    22921 atttccgccc gtgatttgat tctgcttctg ggtggcttgt tccttatctg gaaagccagc
    22981 aaggaaatcc acgaatccat tgaaggtgaa gaagaagggc tgaaaacacg cgtttcatca
    23041 ttcctcggcg ctatcgtgca gattatgctg ctggatatta tcttcagcct cgactcggtg
    23101 attaccgctg tgggtctgtc agatcacctg tttattatga tggccgccgt ggtgattgcc
    23161 gtaggcgtga tgatgttcgc cgcacgctcg attggtgatt ttgtcgaacg ccatccttcg
    23221 gtaaaaatgc tggcgctctc tttcctgatt ctggtgggct ttaccctgat tcttgaaagt
    23281 ttcgacatcc acgtaccgaa aggttacatc tacttcgcga tgttcttctc tattgcggtt
    23341 gaaagcctca acctgattcg caacaaaaag aatccgctct gatactccgt acgctctcct
    23401 gcgggagggc gtactcactc ctgttaccct cacagtttaa gattttcctg ctttcaagat
    23461 atataacgtc ggtttataaa aagactatta tcataggtgg gccaaatgag gataaccgga
    23521 tgaaaaaatg ggcagtaata atttctgcag tcggactggc gtttgctgta tccgggtgtt
    23581 ccagtgatta cgtcatggcg accaaagatg gccgtatgat tttgaccgat ggaaaacctg
    23641 aaattgatga tgataccggg ctggtgagtt atcacgatca gcaaggtaac gcgatgcaaa
    23701 ttaaccgtga tgatgtttcg caaattattg aacgttaaca aataaggtca gcatccggct
    23761 ggccttaaga tttttctctt tcccttttcc cttccctctg ccatttttat attccttatg
    23821 tcgtgattat aaaaaggaaa cggctatgca atatcaccgt ataccccaca gttcgctgga
    23881 agtcagcacg ctggggcttg gcacgatgac gtttggtgaa cagaacagcg aagccgacgc
    23941 ccacgcacaa ctcgactatg ccgtcgctca gggcattaac cttatcgacg ttgccgaaat
    24001 gtacccagta cctccgcgcc ccgaaactca agggctaacc gaaacctacg tcggcaactg
    24061 gctggcgaaa catggcagcc gcgaaaagtt aattatcgcc tccaaagtga gcggaccgtc
    24121 gcgcaataat gacaaaggca tccgcccgga tcaggcgctg gatcggaaga atatccgcga
    24181 agcgctgcat gacagcctca agcgtctgca gactgattac ctcgatctct atcaggtgca
    24241 ctggccgcag cgcccaacca actgcttcgg caaactcggt tatagctgga cggattctgc
    24301 gcctgcggtt tcgctgctgg atacgctgga cgcactggca gagtaccaac gcgcgggaaa
    24361 aattcgttat atcggcgtgt cgaacgaaac tgcatttggc gtaatgcgct acctgcatct
    24421 ggcggacaaa cacgatctgc cgcgtattgt caccattcag aacccctaca gcctgttaaa
    24481 ccgcagtttt gaagtaggtc tggcagaagt cagccagtat gaaggggtcg aactgctggc
    24541 ctattcgagc ctgggtttcg gcacactgac cgggaaatat ctcaatggtg caaaacccgc
    24601 tggcgcacgt aatacgctct ttagtcggtt cacccgctat agcggtgagc aaacgcaaaa
    24661 agccgtcgcg gcgtatgttg atatcgccag acgtcatggc ctggaccctg ctcagatggc
    24721 gctcgcattt gtacgccgtc aaccgtttgt tgccagcact ctgctgggcg caaccacgat
    24781 ggagcagctg aaaactaacg tcgaaagttt gcatctggag ttaagcgaag acgtattagc
    24841 tgaaattgaa gcggtgcatc aggtttatac gtatcctgca ccataagatt aacgccggtt
    24901 aaaaccggcg ttaaatatta atgacggcgc tgccagatcc acagcgccgt tattgccagc
    24961 gcaaacagcg caccgaagcc aatgccaatg ggcacgaccg ggacgcctac cattaccgcc
    25021 agcgagtaaa tgcccagcat caacaacatg gcgctgtttt cgccaaggtt ttgtactgca
    25081 atcgcattgc ccgccccgac gcttttttta ccccgctcct gtagcaacgc attgagcgga
    25141 acgacaaaaa agccccccag cacgccaatc agcatcaaca aagcataggc tggcagcagc
    25201 tcgtgttgca gggagaaaat cagtaccacc acgccaatca aaatcccggc tggcatacag
    25261 cgtgacacgg tttccagcgt aactaacttc gctgccgcac ctgcgccaac cacgatacca
    25321 atcgcgacca tcgcgttgag ataggtcggc gtagcgttat cggtaatgcc cagcgccacc
    25381 ggtacccaca gcaccaacag gaaacgcagc gtgacacccg ctccccagaa taaactggtg
    25441 cccaccagcg aaaaacgcgt ttcaccattg cgccatagcg aggtgcaggc attcaggaaa
    25501 ctgcgggtca tgttgatgag attccaggac tgccccggac gcgccgccgc cagtttggga
    25561 atgtagatat tggcaacgac cgcaccaccg taggccagtg cgcatgcggc cagggcgacc
    25621 aggacatgcc agtcagccag cacaccaccg gctacggaac cgagcaaaat cgccgctatg
    25681 gtagacgctt ccattaaacc gttagctttt actaacttac tacccgtggt taattcgccg
    25741 agaataccgt atttcgccgg tgaataggct gcagcaccaa cacccaccag cgtatagccg
    25801 agaaacggat tgataccaaa gcagatactg gctgcgccca gcagcttcag gccgttggca
    25861 aacatcatca cccggccttt ggcgaagcta tccgccacct gcccgacaaa cggcgcaaaa
    25921 agaatgtaag cacctacaaa caccatttgc aggatgggct ggctccactc cggatagaac
    25981 tgcgctttca gtaacgccag agtggcaaac agtagggcat tatcgccaaa cgcagagaga
    26041 aactgcgcca cgataaccgc tttcatcccc ttcgaccaca acgaagtgtt agtgtgcact
    26101 gactcactca tcgtgttgtt ccgcttcgtc tacccagctt ttcaacgtga caaagtcagg
    26161 tttgccgctg ccaagtaatg gcatctgttt cggatagcga atatcgcgcg gtacagcaag
    26221 ctccggcacg ccgtgctcgc gggcatactg ttgcaactta tcgcgcgtca gttcgttatc
    26281 tgtggtgaaa agcaccagcg cctcgccttt gctggcatcg ctcttaatcg cagtggcatg
    26341 gactttatct ggcgaaacac caagtgccag ttgttccacc atttccagcg acaccatttc
    26401 gcctgcaatt ttggcaaagc gttttgcgcg gccctgaatc tgcacaaagc cctgctcgtc
    26461 aaaacgcacg atatcgccag tgtcatacca gccgcgctcc atttcgccgc gaacattctc
    26521 ggcggtgggc acttccagta caccaggctt ctccacccgc agatagccgt tcattatgtt
    26581 cggccctttc agttgcaggc gtccgccctc ttcgatacca ggaaccgaca acaggcgcgc
    26641 atccattcct ggtagaatac gccctaccgt accgggtttc gccgccatcg gtacgttgat
    26701 agaaacgaca ggcgcgcatt cggtcacacc gtagccttca aggatgcgca ggccaaattt
    26761 atcctgccaa agctgtttag tactttcttg tagtttttct gcgcctgcca ccacatagcg
    26821 tagacgatag aagtcatacg ggttggcaaa gcgcgcgtag tgaccgagga aagtcgaggt
    26881 accgaacaac acggtgcaac tgcggtcata caccaactcc ggcacaatgc ggtaatgcag
    26941 cgggcttgga taaaggaaca cttctgcacc tgtgagcagt ggcgtaaaca ggcctaccgt
    27001 aagcccaaag gagtgaaaca gcggtaacgc cgacataaag cgatcgttgg tggtgaagtc
    27061 ggcaatcgtt ttaatctgct cgacgttcgc cagaatgctt ttatggttat ggacgacgcc
    27121 tttcggatgg ccttcagaac cggaggtaaa aaggatcagc gcctcttctt ccggctgctg
    27181 tttaacctgt gccagacgcg gcatcagcaa atgagcgaag atccacactt tgtcggcagt
    27241 ggtgacatct gcttttaaat cttccagata gacccagcgt acctgagtaa gttgctccga
    27301 cagatgccag agtttgcctt tatcgagaaa ctggcgggaa gtgaagatgg ttttgatttc
    27361 agccgccgta atagcactgg tcagcccttt taccccggcg gtgtagttca tcattgcggg
    27421 aatgcggcga cgggcgatgg ccccaaaaat cactgccgca ctgatgcctg cattgggcag
    27481 cattaagccg atgcgttcgc cttcaacact gtatttttca aggatgcgtc caacaaacag
    27541 cgttttcgta agcaatttgc gataggagtc tggggtaaag ttgacgtctt cgacacattt
    27601 cttcccggct ccgaagcggt acattgcgct cagtaaagat tcgtacagcg tttcacgcgg
    27661 gcgcaccgcc atacgcgctt ccatcattat ttgatgcagc atttcgccag cgattttgcg
    27721 acggtcacgg gcacgcggtg catccggcat ctgcacctgc gttggtggca aaatatgcag
    27781 cgtaatttgc gggaacaagc gacgtttaac cagacctttc aggcggctga agtgcgtaag
    27841 ttccgcccct tcaatacgca caggaattac cgttgcacca gacttcgccg cgacaaaacc
    27901 cgcgccatcg tagattttca tcagcgagcc agtggtagtg attcgtccct cagggaaaat
    27961 caccaccgga cggccttgtt ccaccagacg aaccagatgt ttaatcgcca taggttgcgt
    28021 cgggtcgaga ggaacaaagt cgataaatga tttcagccaa cgcatatacc actgttgact
    28081 tattgaggtg taaacggcaa ataccggacg tacgggtaaa aacaatgcca gcagtatgcc
    28141 atcaataaaa gagacgtgat taggcgtgat tagaacgcgc tcgcccttca gtgcctggtt
    28201 gtcacccgta acgcgaacgc gatacaaaac acggcacaca tttcgaaaaa agctaaaaag
    28261 cattccaact ccctttgctc tgattcagta aaagcgaatg gagggagatt acacgagata
    28321 aagaacgcga gcgacagtaa attaggtgcg aaaaaaaacc tgcgcatccg cgcaggttgg
    28381 tgcaagagac agggtacgaa gagcgtaccg aataatctca ccaatcaata cctctgggat
    28441 cttgattgtg gtctgcacga cgactcttcg ccagcgagaa aacgcaaagg aatgaaggga
    28501 aatgcaacga ggtgtgtaaa ttgtcggtta ctgttacaga ttgatgaccg gcaaaaaaaa
    28561 acctgcgcat ctgcgcaggc tggtgtaatt catgtgctca acccgaagtt gacttcacct
    28621 atcaatacct ctgggatcac cactttagca acctgaagcc aaacgccacc agcagtcaat
    28681 cgcaacagcg tttcgcaaag tgtaaccaaa ggtttgcaat ctcttttttt gtcttactta
    28741 tttgcgtttg gctcacattc ccacgatgaa agcatgcccc cccttgaacc aacgggcgtt
    28801 ttccgtaaca ctgaaagaat gtaagcgttt acccactaag gtattttcat ggcgaccata
    28861 aaggatgtag cccgactggc aggcgtttca gtcgccaccg tttcacgcgt cattaataat
    28921 tcacccaaag ccagcgaagc ttcccgactg gctgtgcata gtgcaatgga gtctcttagc
    28981 tatcacccga acgccaacgc ccgtgcgctg gcgcagcaga ccactgaaac gatcggtctg
    29041 gtcgttggtg atgtttccga tccgtttttc ggtgcaatgg tgaaagcggt cgaacaggtg
    29101 gcttatcaca ctggtaattt tttattgatt ggcaacggtt accacaacga acaaaaagag
    29161 cgtcaggcca ttgagcaact gatccgccat cgctgtgctg cgctggttgt ccatgccaaa
    29221 atgatcccgg atgctgattt agcctcatta atgaaacaaa tgcccggtat ggtgctgatc
    29281 aaccgtatcc tgcctggctt tgaaaaccgc tgtattgctc tggacgatcg ttacggtgcc
    29341 tggctggcaa cgcgtcattt aattcagcaa ggtcataccc gcattggtta tctgtgctct
    29401 aaccactcta tttctgacgc cgaagatcgt ctgcaagggt attacgatgc ccttgctgaa
    29461 agtggtattc cggccaatga ccggctggtg acatttggcg aaccagacga aagcgggggc
    29521 gaacaggcaa tgaccgagct tttgggacga ggcagaaatt tcactgcggt agcctgttat
    29581 aacgattcaa tggcggcggg cgcgatgggc gtgctcaatg ataatggtat tgatgtaccg
    29641 ggtgagattt cgttaattgg ctttgatgat gtgctggtgt cgcgctatgt gcgtccgcgt
    29701 ctgaccaccg tgcgttaccc aatcgtgacg atggcgaccc aggctgccga actggctttg
    29761 gcgctggcgg ataatcgccc tctcccggaa atcactaatg tctttagtcc gacgctggta
    29821 cgtcgccatt cagtgtcaac tccgtcgctg gaggcaagtc atcatgcaac cagcgactaa
    29881 ccgcagttaa agcaattcca gcgccagtaa ttcttcaatg gtctggcgac ggcgaatcaa
    29941 ccgcgcctga ccattatcaa acagaacttc tggtaacagc ggacgactgt tgtagttgga
    30001 tgacattgat gcgccatatg cccccgtatc atgcagtacc agataatcac ccgccttcac
    30061 ttccggcaag gcgcgggttt cgacatttcc cccttcctgc tgggtaaaga catcgcccga
    30121 ttcacataac ggcccggcga cgacggtttc caccgttggc gcgtgttcca gagaacgacc
    30181 atcagctgcc agggcactga tatggtggta actaccgtac attgccgggc gcatcagatc
    30241 gttgaacccg gcatcaacca gcacaaagtg gcggctaccc atttgtttga cgcttcgcac
    30301 ttgagtaatt aatacgccag cctgcgctac cagaaagcga cccggttcaa tttccagttt
    30361 cacaggatgg cccaaatggc gggcgatttg ctcacgcgcg gcattccata gaccataata
    30421 atgttcagta tcaaccgcct cttcaccctg ttgataagga atagaaagcc caccgcccgc
    30481 agaaatagcc tgtaaatcct gaccgaattc gaggacctga cgcaccatag caccacatac
    30541 ctgttccaga tgggcataat cgacgccaga accaatgtgc atgtgaatgc cgaccagctg
    30601 tagatgatga cgttgtatca cgtccagtgc ggcgggcaga tcggtgtacc agataccgtg
    30661 cttgctgttt tcgccaccgg tattggtttt ttggctatgc ccgtgaccaa accccggatt
    30721 aacacgcagc catacccgat gccctggcga aacctgaccc agttggtcga gcatatcaac
    30781 agaacccgca ttcaccggaa tttgcaattc actgacgcgt tcaagcgtcg cctgatcgat
    30841 aacatctgcc gtaaaaacaa tatcatcggg gtgcgtttgc ggattgtaac ccgccgccag
    30901 tgcacgctct atttcgccta acgagacgga atccactttt acgccctgct cacgcattaa
    30961 gcgcaaaata tgaatattgg aacaggcttt ctgtgcaaag cgcaccacat caaactgttt
    31021 cagcgctgca atctgccgac gaataatttg cgcatcgtag acccacaccg ggcagccaaa
    31081 ttctgcgggc aaacgcagca gattttcggc ggtgagatcg gtatcagtgc tgaacagtga
    31141 atgtggcata acaaactcca gataagtgct tttttatgat tacgccacat cataaaaaga
    31201 ataaaaaata tcgatttgtg tcgagtctat gcaaaaatga tatggattac cggattgcga
    31261 gagagcgcta atggccgccg ttaacttacg tcatattgaa atttttcatg cggtaatgac
    31321 cgccggaagt ctgactgagg cggcacacct gctacacacc tcacagccaa ccgtcagccg
    31381 cgaactggcg cgctttgaga aggtgatcgg gctgaaattg tttgagcgca tacgtggacg
    31441 attacatcct accgtgcaag gactgcgtct gtttgaagaa gtgcaacgat cctggtacgg
    31501 actggatcgc attgtcagtg ccgcagaaag tctgcgcgag tttcgccagg gagaactgtc
    31561 tattgcctgc ctgccggtct tttcgcaatc ttttttaccg cagctcctgc aaccctttct
    31621 ggcacgttat cccgatgtca gcttaaacat cgtgccccag gaatcaccgc tacttgaaga
    31681 gtggctctcg gcccagcgtc atgatttagg actcactgag acactccata cgcctgcggg
    31741 aacagaacgt accgaattac tctctttaga tgaagtgtgt gtgttacctc cgggccatcc
    31801 gctggcggta aaaaaggtat taacgccgga tgattttcac ggtgaaaact acatcagcct
    31861 ttcccgtact gacagctatc gccagttgct ggatcaattg tttactgaga atcaggttaa
    31921 acgacgcatg atcgtagaaa cccacagcgc cgcgtcagtc tgcgcaatgg tacgggcggg
    31981 ggtaggcgtt tcggtagtta acccactcac cgcactggat tatgcggcaa gcggtttagt
    32041 ggtgcggcgg ttcagcattg cggttccatt caccgtcagc ctgatccgcc ccctgcaccg
    32101 cccgtcatca gcgctggtgc aggcgtttag tgagcattta caagcgggat taccgaaact
    32161 ggtcacttct cttgacgcta ttttgtcgtc agctacgaca gcataaaagc gacagcatcc
    32221 tcggcatgga tcgccgcggt atcaaacaca ggcagaacac tgcgctcttc tggcaccagt
    32281 aaaccaattt ctgtgcagcc aaaaatgacg ccctgtgcgc cctgttctgc aaggcgagca
    32341 atcacttgcg cataataagc gcgtgatgct tcggtaaatt gccccagaca cagttcttca
    32401 aaaataatct gattaatttt tgcccgttca tccgcttcag gaataagaca gttgatggaa
    32461 aattgttccg tcagccgccc gcgataaaaa tcctgttcca tggtgtaacg tgtacccagc
    32521 agcgccacac gagtcattcc tgccccggta attgcacgtc cagtggcatc cgctatgtgt
    32581 aagaaaggca gagagcaacg agactcaatg gcatccgcca ctttgtgcat cgtattggtg
    32641 cataacacaa taccttctgc gcccgcccgc tgtaagccaa gcgccgcctc agccagaata
    32701 tccccggttt tgtcccactc accgcgacgc tggcactctt ctatttcatg aaaatcgacg
    32761 ctatgtagca gcacttgcgc agagtgaagc ccaccaagcc gctgtttaat gccttcattt
    32821 atcagacgat agtaaggaat agtggattcc cagctcattc ctcccagcaa accaattgtt
    32881 ttcattcctc tctcctgatg tgtgttaccg caacaaggct gaataaggaa cgagacaaac
    32941 gcctcaacgg ccaggtgcct aatctctatt aacgaaaaaa gggccggatg tacagcacat
    33001 ccggcccgtg aaatcagacg ccgatatttc tcaacttttc gcctgccatc agtttgcgct
    33061 cgatatgttc cagcgtgaca tttttggttt ccggaatgag ccagaaagta atgcccacaa
    33121 acgcaatgtt caacgcagtg tagagccaga acgtaccggc agcgccaatg ctatcaagca
    33181 gtgtcaggaa ggtcgcgccg ataatcatat tcgacaccca gtttgtcgtc gtcgaacagg
    33241 tgatgccaaa atcgcggcat ttcagcggct gaatctcaga gcacaggatc cacaccactg
    33301 gcgcggcgct catcgcataa ccggcaatac acatcatcgt catgccaaca gagagccagg
    33361 acaagccact ggaagccgta ccgttatcaa actgcatcag gcaatagccc agcaccagag
    33421 tgcctaacgc catcacgctg aaaccaattt tcagagccgg cttacgccct gctttatcta
    33481 ccgtaaagac cgcaatgaag gtagcgaaca taaaggtcag ccccacgacc agagtcgcaa
    33541 tcatctgttg ttctgtggtc gtaaagcccg ccattttgaa gatacgtggc gcgtagtaca
    33601 tgatgatgtt cataccggta aactgctgca tcgcctgcaa caacataccg agaaacacag
    33661 cacgacggac gttacggttg atcttaaaca gtgcccaacc gccctgtttt aacttcaggc
    33721 tttcacgaat ttcgttgagt tcttctcgcg ctttttccga cgtatcgcgc agcatacgca
    33781 acacttcttc cgcctcaata tgacgcccct tttccgccag ccagcgcggg ctatttggca
    33841 ggaagacaac cagaataatc agcaggactg ctggtaaagc aagaaccccc aacattgcgc
    33901 gccagttacc gctataactg aacgctgtat cggataaaaa cgccagcacg atgccgagtg
    33961 tgaccatcaa ctggtacata ctgatcatct taccgcgaac gttttcactt gccatttcag
    34021 aaagatacag aggagcggtg taagacgcga tcccgacagc aatgcccagc accacacgag
    34081 cggcgattaa catctctacg ctggtcgcaa aagcggaccc tatagaaccg agtacaaaca
    34141 ggatggcccc cgccatcagg ctgtatttac gccccaggcg gaacgacagc caaccattaa
    34201 acagcgcacc aattgctgcg ccgagcatca tgctactaac cacccattcc tgcaaacggc
    34261 tggtcagcac aaagtgatcg gtaatgaacg gcaaggctcc ggcgattacg ccgatatcaa
    34321 gaccaaataa caatcctgcg accgcagcag ctaccgaaac aaacatattc atacgccgcg
    34381 tatcccgcaa agaacgtggc gttaaagcag attccgtatt gatagtaacc attttttcct
    34441 gccagcagag agtaagacat agtgaaaaaa tacgtgaaca attcacacag gtgtcaggtc
    34501 ggaaatagca taaatatgga ttaaattgct gcgacatgtc gttatgtgat ggatattaca
    34561 attttcaaat taagttgaat aattgagatt attattaacc aactaatttt aaagcagata
    34621 aaattcataa agttcattaa ttgataattg atatggatta tttcataacc atgatatgga
    34681 ttatgatgat ctacaggtat aaaaaaccct gccatgcggc agggtcataa aagtaagaag
    34741 aatggattaa cgagccagcc aaccgccatc cacggcaatg gtataaccat tcacataatc
    34801 tgaagcactg gaggcaagaa acactaccgg ccccatcagg tcactcggca gtccccaacg
    34861 gccagctgga atgcggtcga gaatttccgc gctacgttgt tcatctgccc gtagttgttg
    34921 agtattgttg gttgccatgt aacccggagc tatcgcatta acattaatgt tgtgtttagc
    34981 ccattcattc gccatcaatc gtgtcacgcc catcacgccg ctttttgatg cggtataaga
    35041 aggcacacgg atcccgccct ggaaggagag cattgacgcg atattgataa tcttgccgcc
    35101 attgccttgc gcgataaagt gtttcgccgc tgcctgagac atgaagaata cgctcttgat
    35161 attcaggttc atgacatcgt cccagtcttt ttcgctgaac tcgagagcat cttcgcgccg
    35221 aatcaatccg gcgttattca ccaggatatc aatatgacca aactcagcta ccgcgcgatc
    35281 cagcagtgct ggaatgccat caatctttct cagatcggcg gtcaggctta aaaaacgacg
    35341 ccccagcgcc gtgacctgct tgatggtttc agtcggttca acgatgttaa tgccaacaat
    35401 gtcacagccc gcttgcgcca gccccaacgc catcccctgg cccagtccag tatcacaacc
    35461 agtgacgacc gcaactttac cttcgagaga aaatgcactt aaaatcataa caatacctta
    35521 ttcgtttatg cccacaacta gcgcaaatct ttaacggcca catggtccat atcatcaaag
    35581 acctggtttt caccgaccat gccccagata aaggtataag ctttggttcc gacaccggaa
    35641 tggatcgacc agctcgggga gatcaccgcc tgctcgttat gcatcacaat atgacgcgtt
    35701 tcttgcggct gccccatcat gtggaaaacg caggcgtcat catccatatt gaaatagaaa
    35761 taaacttcca tccggcgctc gtgggtgtga cacggcatgg tgttccacaa gttacccgga
    35821 gccagctccg tcatccccat actcaattgg caggtttcca gtacatccgg gacaaaatat
    35881 ttgttaatcg tgcgacggtt actggtgagg ttatcgccta acgtgactgg agatacttcg
    35941 tccggtgtga cttttttggt gggatacgtc gtatgcgcag gtgcgcaatt gtaataaaac
    36001 ttcgccggag tagcggtatc aatactggca aagacaactt cttttgcgcc tttaccaaca
    36061 tacagggctt cgcggtgacc gatttcatag cattgaccat cgacggtaat cgtaccggca
    36121 ccgccaatat tgataacacc taactcgcga cgttccagga aatagcttac gccgagttgt
    36181 ttaccaactt ccccgccaac ggaaaccgtt ttagttaccg gcataatgcc gccaacaata
    36241 atacggtcaa tgtggctgta aaccatggtg tactcatcgg cgacaaatac cttttcaact
    36301 aaaaattcat tgcgcagccc ctgggtatcc agcgtttttg catgcgcact gtggatgctc
    36361 tgtcttacgt ccacatcaac ctccgataat cagtgaagcg tgaaaataga aaacgatagt
    36421 gaaacactgt ttcgttttct ctataagggg atgatatgcc cacgggatag ggttttcaat
    36481 taaaaataaa acaatgtttc atttttaagt taaggactga aaaaagtgca gtgtcgatca
    36541 cgaatatgtc atgagaatgg aaaaatcagg gagccctgaa aatgtatgtc gactcgccag
    36601 ccaccattat tcaacagatt gatgacggct gatatttatc ggtaaggagg aaatgcagag
    36661 ctattcgtca cgttcaatgg tcaatgccac gccctggccc ccgccgatac aaagcgtagc
    36721 cagtcctttg cgggcattac gtttcaccat ttcatgaacc agagaaacga ggattcggca
    36781 accggaagcg cctattgggt gaccgagtgc gatcgcgcca ccattgacat tgacccgacg
    36841 ctcatcccat tcaagcatct tgccaaccga aagcgcctgt gcagcaaacg cttcattagc
    36901 ctcgataaga tcgacatcag ccaactgcca gccaacacgc tccaggcaac ggcgggtcgc
    36961 atacaccggc gcaattccca tcaatgccgg atctacacca acgctggcaa atgcgcggat
    37021 gcgggccagc acgggtaaat tcaacgctcg tgctttggct tcgctcatca tcattactgc
    37081 agctgcgcca tcgtttatgg atgatgcatt acccgctgtc acagagccga gactatcaaa
    37141 tgaaggattt aaacgggcta agccttctgc actggcgtca gtgcgtggct gttcatcggt
    37201 atctacaacc aacgtctgac cgttactttg ggtcattacc gggacgatct catctttaaa
    37261 tcgtccggcg tcaatcgccg ctcgcgcttt ttgttgcgag ctaagtgcgt aagcatcctg
    37321 caactgacgg ctgatgccat attcgcgagc cagattttcg gcggtgacac caatatgata
    37381 atcattgaag gcatcccaca acccatcatg cacaagactg tcaaccaact ggctattgcc
    37441 aagctgtgca ccggtgcggc tatcagtcag aacatgtggt gcgcggctca tgttttcctg
    37501 gccaccggcg atgacaatat cagcctcgcc acactgtatc gcctgagtag ccagatgcag
    37561 tgctttaagc ccggaaccgc aaacgtcatt aatcgtgatt gcagaaacgc tattaggaag
    37621 accaccttta atagccgatt gccttgccgg attctgccct gcccctgcag tcaacacctg
    37681 accaagaatt acttcatcca ccgcatatgc aggaacgccg gtacgttcta ttaacgcttt
    37741 cacgaccaga ctaccaagtt ccacagcgga atgacccgct aacgcaccac gaaagcagcc
    37801 gataggtgtc cgtaacgccc cgacaatcac aacgtctttc atcacaacct cgcaccaatt
    37861 aacagtgcaa tagtaaatga ttgttaatca cagttatctt aattgtttaa aaaaagtgat
    37921 ttttatcaca aaggaaatac gcctgaccag cggtcagaga cataactggc acgtaaggtt
    37981 tgcaaccact aacccaccaa tagagaggta gaaagggcgt taatctccca tacttaacct
    38041 ggtttatggt aaattgccct ccattttgtt taatttgtag atgatacgtt cagataatgt
    38101 ctaatatttg gtcaaaagaa gaaactctgt ggagtttcgc gctctacggc acagccgttg
    38161 gtgcaggcac gctcttcctt cctattcagt taggttcggc aggggctgtg gtcctgttta
    38221 ttactgctct ggtcgcctgg cctttaacat attggccaca taaagcctta tgccagttca
    38281 tcctctcatc aaaaacatca gcaggtgaag ggataacggg cgcagtaaca cactactatg
    38341 gcaagaagat tggtaatctg attaccacgc tgtacttcat cgcctttttt gtcgtcgtgt
    38401 tgatatatgc agtggcaatt accaactcac ttacagaaca gctggcaaag catatggtta
    38461 ttgatcttcg catccgtatg ctagtgagtc tgggtgttgt attaatcctg aatctcattt
    38521 ttctgatggg acgccatgcc actattcggg taatgggatt tttggtattc ccattgattg
    38581 cctatttctt atttctttct atttacctgg tcggtagttg gcaacctgat ctattaacaa
    38641 cccaggtaga gttcaatcag aatacccttc accagatatg gatatcgatt cccgtgatgg
    38701 ttttcgcctt tagccatacg cccattattt ctacgtttgc catagacaga cgtgaaaaat
    38761 atggcgaaca tgctatggat aaatgcaaaa aaattatgaa agtcgcttat ctcatcatct
    38821 gcataagtgt actgttcttt gtctttagct gcctgctttc tattccacct tcgtatattg
    38881 aagcggctaa agaagaaggg gttaccattt tatcggcgct ttctatgctg ccgaacgccc
    38941 cagcatggtt gtcaatttcc gggattattg tcgcagtagt tgcgatgtcg aaatcattcc
    39001 tgggtacgta ctttggcgtt attgaaggtg ccacggaggt cgtcaaaaca acactacagc
    39061 aggttggtgt aaagaaaagt cgtgcattta accgcgcact atcaattatg ttggtatcgc
    39121 tcattacctt cattgtttgt tgcattaacc cgaacgcgat ttcgatgatt tacgcgatca
    39181 gcggcccgct cattgccatg atacttttca tcatgcctac gctgtcaaca tatctcatcc
    39241 cggcgcttaa accctggcgt tccatcggaa atctgattac gctgatcgtg ggtatcctgt
    39301 gcgtatcggt aatgttcttt agctaatatc cgttgtgaat ggttcaaaat tgcaaaaatt
    39361 ttgaaccatt ccagttttca taatgttcat ttgttattat tccgctctat cacttctctc
    39421 gtcatatcct agtattatca gttagttaaa caaacaaaga gatctgaaca tcttaaataa
    39481 gactatttaa gatgcataac ttagattcgc aagatatctt ctggtcattc aaaaacaatt
    39541 tgcgatatag atattcttat accatgagat agttatctgg accgctctca accatgcaag
    39601 attaaatcag tgaaacataa tcatatttga taacgagaaa tgcattttta aatgccttac
    39661 tcagaattat agcaaataca gattaatcgc aatttttccc ggcaaaatta caaaatcatg
    39721 gtgtattgac atcatcaata accaatgaaa ttatgcaatt atatacggat agggaggttc
    39781 ttaacatggg gctttgtagt cgttataaaa gtcttacatg caatagttgc tcaatgcatt
    39841 gccaaataat gccagaagag tcaccgcgtt tgcagtattg cgcaaactcg tgtttttgta
    39901 tgtggcccga agaaagttca tattttaatc gtggtgtggt ggaaggtatc ttaacaaaaa
    39961 accacaatgc gagattaagc ggatatattt ttgtcgattt ttcagtaagc tttttacgtc
    40021 tattccttga aaaagactgg attgactatc ttgcaagtac tgacatgggg attgttttag
    40081 tcagcgaccg aaatatgcaa tcgttagcta actactggcg aaaacacaac tctgcaatat
    40141 ctgctgtcat atataatgat gatggtcttg atgttgccaa tgaaaagatc agacaactat
    40201 ttattggtcg ttatttatca tttaccagag ggaacacatt aactcagatg gaattcacca
    40261 taatgggata tatggtttct ggttataatc catatcagat tgctgaagtt ctggatatgg
    40321 atatccgtag catctacgcg tacaagcaac gaatcgaaaa gagaatgggt ggtaaaatca
    40381 acgagttatt tattcgttca cattcggtcc aacattgata ctcaacaatc tgccagaatc
    40441 atactctgct tatacgggca tctattgaaa tgcccgtatt ttacaaataa gcagtaaccc
    40501 caagagtaaa taacatggta tttaaaacca tcatacgaaa aattcagaag cattacgaaa
    40561 tatgaattta caaacaatag tggcataaat gttaatcatg ttaatttacg taaagtttta
    40621 cgttgcgaca ttaaagcgtc atttcaatca ttatgataaa tataaaatta atatatattt
    40681 atgtcgtaaa taccaatata cttagcaaac tatgtgattt ccatttcgat tgatttagtg
    40741 tctattgacg tatgtactgg attattaacg ataatatcga gttctggcct gagcaccgaa
    40801 aattaatatc ggtacataac gccgatctta acgtcgttct gacaacgcca gccagtcgtt
    40861 gtttatcact tctacttgaa gcttttcctg atgtggttgc acaacaagat tttttcacca
    40921 gagtctggga agaagaaggt atgcgtgtgc caactaacac gttatatcag aacatatcca
    40981 ttatcagacg cggatttcgc gctgttggtg ataccaccca ctcgcttatt gcaaccgtgc
    41041 cgagaagagg attcaagatt cataatgaca ttaacataca aaatcatgca ataaactctt
    41101 caacagacgc acatacacac aatgccccac ctgccgtaaa aggtaatgcg gggtacaaag
    41161 agagcattgg tggcgcaaac aatttcaata acaaaatcct caaacatata aaaagttatc
    41221 taattatgtt gagcatattt gctataggcg tatattctgc acattggcta tggaataata
    41281 atcaaccgaa gccattcttc aaggattaca agactgttgc ggaaattaat ggctgccatt
    41341 ttaatgtgac agaagataca attgatgggt tgaaagagtt cgataaatat aagacacgga
    41401 tactggattc ggggattaac tgtaaaaaat atccgtggtt atacttccct cttgcaaaat
    41461 cctcaccagg gatgattgtt atggcatgca ataaaaacta taaccaacat gaagtggcag
    41521 gctgtttaac cctgtcttac cgtgaggcta atcgtgattg attataaaaa aaacttatta
    41581 tttattttag tttttatcag tgggtttatt ctcttcattg tttactctta tactgcagaa
    41641 aaaatgatat ataatgaaac atgcactgca aattgggtaa tttttaatga caaggggcga
    41701 gcaaatctta ccatcgactt tatgtataac caaaaaaata aaacaggaac tgttgcgttg
    41761 agcggaacct ggcaacaagg taacagagaa agtaagtcaa tacggcgaaa tattgaatac
    41821 acatggattg aaaactatga cacagcccat ttaacatcaa agaaagttaa taaatttgag
    41881 atcatggatc aagtcgatga tgatagactt gcagaactta ttcctgattt ttatgtcttt
    41941 ccagaaaaaa gtgtaagcta taatatacta aagtaaggta agcatgcttt tattttgagt
    42001 attggtaaca gagcaataat gcattgtaca aggtaaactt aaatagataa caaaaagatg
    42061 gaacctcgct aatcataaaa caataaaatt aaatatgctt gtagtatatg ccagtataaa
    42121 gcatcaaagt tttgatcaac atctttcatt ttagatatca ccttgcaatg taaaatatca
    42181 tgtatcaaca acatctggtg caaatccatg agtcgaactc aacattcatc ttagctctat
    42241 tattattcct tcgtacagtc gatgtaaaca atacagaaag aggattatta agaaccagtt
    42301 tacttagaga atcaatagag gaaaggacta acgtttcttt aaaagaattg atttcatcat
    42361 ctgttaaact aaactcatca ttgacagatc gtgagatata actgttttta actttactct
    42421 ttacgttgac tttactgaca gaattaacat tcacatatct tgaatttagt acccatgatg
    42481 ttgtttgcgt gagaaccttc tcagcattaa ggaatttttt taacggaatc cttggtttct
    42541 ttttcgagtc cgaatttaca atatcatgca tatagaccat ttcatgaatc tgcgaaaact
    42601 caatgtccat tatatacctc acatttttac cgtgactcga tgttactgtt caataatcac
    42661 cttccatcaa tactaaattt aataccccta atgtgccgat aacaaatata gtcattctac
    42721 gtaacgtctc cataaggtga taaccttgat caaatgaatt tcgaaaataa taaaggaaat
    42781 cttttgagat gtttgtcacg aataaagcta tttatgttac caatatcatt tcgagtgtgc
    42841 acactatcta tctgtttttt caggatataa aaaacaacat gtaagttatg taaattgccg
    42901 atgctactaa gtaacattat ggtaaaaaaa gtaaaaatga gcgatttttg atagaataa
//
LOCUS       DADXDL010000031        42391 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.031, whole genome shotgun sequence.
ACCESSION   DADXDL010000031 DADXDL010000000
VERSION     DADXDL010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 42391)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42391)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42391
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.031"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(40..192)
                     /gene="kil"
                     /locus_tag="IRB70_001981"
     CDS             complement(40..192)
                     /gene="kil"
                     /locus_tag="IRB70_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001243351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitory peptide Kil"
                     /protein_id="HBC0631898.1"
                     /translation="MRNEIAINHQMLRAAQNKAVIARFIGDSKMWLEANKAMKSAINL
                     PWYRRK"
     gene            complement(177..311)
                     /locus_tag="IRB70_001982"
     CDS             complement(177..311)
                     /locus_tag="IRB70_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631899.1"
                     /translation="MMHFQLAGSGVMSAFYPHESELSRRVKQLIRAAKKQLEALCAMK
                     "
     gene            complement(536..1159)
                     /locus_tag="IRB70_001983"
     CDS             complement(536..1159)
                     /locus_tag="IRB70_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001597931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631900.1"
                     /translation="MSSIRLTTRMKEEIARNALIKSGVFTELEEVTKLKNQLALDARV
                     IAFGGKKKTEEVDQLSSKLVAISEELEKMGCSFYSYDVSSTSIYLTVSGRRVGWHSYG
                     KDGNGEDILLPTPTKDKCMFSAEHEITKRFDEICALQQKLEAKKKDIESNVWAALNSV
                     TTVKRLIEVWPESKELLPEEADKASTALPALRVEDLNKMIGLPSEAA"
     gene            complement(1171..1497)
                     /locus_tag="IRB70_001984"
     CDS             complement(1171..1497)
                     /locus_tag="IRB70_001984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HBC0631901.1"
                     /translation="MDAQARRRERRAEKQAQWKAANPLLVGVSAKPVNRPILSLNRKP
                     KSRVESALNPIDLTVLAEYHEQIESNLQRIERKNQRTWYSKPRSEMGVTCVGRQKMKL
                     GSKPLI"
     gene            complement(2019..2876)
                     /locus_tag="IRB70_001985"
     CDS             complement(2019..2876)
                     /locus_tag="IRB70_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBC0631902.1"
                     /translation="MKKAAILIDAGFFMQRVHATHRKHFAEHELTAQCIMKVIWSMVL
                     SHLNGKRQSQERREPLELYRIYFYDCPPLDIQTRLPLPEPGNKTPGRKNFKLEKSYIL
                     RTELHEELRKTRKTALRLGNLVDNKRWQLTTFSLDALMKGTKKWDELTNDDFYYDIKQ
                     KQVDIKLGMDITTLAYEKLVDVIVLVAGDSDFVPAAKHARIKGIDFILDPLRQNVTPS
                     LSEHIDGVQSYSLISGLADALHVEPDPAPDWWEDRKKGKPRGKNNSGKRRYGNTQAES
                     AKKHQRNKR"
     gene            complement(3004..3717)
                     /locus_tag="IRB70_001986"
     CDS             complement(3004..3717)
                     /locus_tag="IRB70_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HBC0631903.1"
                     /translation="MSAKKKPLTQEQLEDARRLKAIYEKKKNELGLSQESVADKMGMG
                     QSGVGALFNGINALNAYNAALLAKILNVSVEEFSPSIAREIYEMYEAVSMQPSLRSEY
                     EYPVFSHVQAGMFSPELRTFTKGDAEKWVSTTKKASGSAFWLEVEGNSMTAPTGSKPS
                     FPDGMLILVDPEQAVEPGDFCIARLGGDEFTFKKLIRDSGQVFLQPLNPQYPMIPCNE
                     SCSVVGKVIASQWPEETFG"
     gene            3818..4018
                     /locus_tag="IRB70_001987"
     CDS             3818..4018
                     /locus_tag="IRB70_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBC0631904.1"
                     /translation="MEQRITLKDYAMRFGQTKTAKDLGVYQSAINKAIHAGRKIFLTI
                     NADGSVYAEEVKPFPSNKKTTA"
     gene            4137..4430
                     /locus_tag="IRB70_001988"
     CDS             4137..4430
                     /locus_tag="IRB70_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lambda phage CII family protein"
                     /protein_id="HBC0631905.1"
                     /translation="MVRANKRNEALRIESALLNKIAMLGTEKTAEAVGVDKSQISRWK
                     RDWIPKFSMLLAVLEWGVVDDDMARLARQVAAILTNKKRPAATERSEQIQMEF"
     gene            4463..5362
                     /locus_tag="IRB70_001989"
     CDS             4463..5362
                     /locus_tag="IRB70_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBC0631906.1"
                     /translation="MTNTAKILNFGRGNFAGQERNVADLDDGYARLSNMLLEAYSGAD
                     LTKRQFKVLLAILRKTYGWNKPMDRITDSQLSEITKLPVKRCNEAKLELVRMNIIKQQ
                     GGMFGPNKNISEWCIPQNEGKSPKTRDKTSLKLGDCYPSKQGDTKDTITKEKRKDYSS
                     ENSGESSDQPENDLSVVKPDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFA
                     GWANDIRLMRERDGRNHRDMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQ
                     AGVTASKPKLDLTNTDWIYGVDL"
     gene            5359..6060
                     /locus_tag="IRB70_001990"
     CDS             5359..6060
                     /locus_tag="IRB70_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication protein P"
                     /protein_id="HBC0631907.1"
                     /translation="MKNIAAQMVNFDREQMRRIANNMPEQYDEKPQVQQVAQIINGVF
                     SQLLATFPASLANRDQNEVNEIRRQWVLAFRENGITTMEQVNAGMRVARRQNRPFLPS
                     PGQFVAWCREEASVTAGLPNVSELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNL
                     YQNMRANALTDAELRRKAADELVHMTARINRGEAIPEPVKQLPVMGGRPLNRAQALAK
                     IAEIKAKFGLKGASV"
     gene            6057..6347
                     /locus_tag="IRB70_001991"
     CDS             6057..6347
                     /locus_tag="IRB70_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein ren"
                     /protein_id="HBC0631908.1"
                     /translation="MTGKEAIIHYLGTHNSFCAPDVAALTGATVTSINQAAAKMARAG
                     LLVIEGKVWRTVYYRFATKEEREGKMSTNLIFKECRQSAAMKRVLAVYGVKR"
     gene            6421..6861
                     /locus_tag="IRB70_001992"
     CDS             6421..6861
                     /locus_tag="IRB70_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein NinB"
                     /protein_id="HBC0631909.1"
                     /translation="MKKLTFEIRSPAHQQNAIHAVQQILPDPTKPIVVTIQERNRSLD
                     QNRKLWACLGDVSRQVEWHGRWLDAESWKCVFTAALKQQDVVPNLAGNGFVVIGQSTS
                     RMRVSEFAELLELIQAFGAERGVKWSDEARLALEWKARWGDRAA"
     gene            6858..7385
                     /locus_tag="IRB70_001993"
     CDS             6858..7385
                     /locus_tag="IRB70_001993"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage N-6-adenine-methyltransferase"
                     /protein_id="HBC0631910.1"
                     /translation="MTIKSNTPAHDKDCWQTPLWLFDALDIEFGFWLDSAASDKNALC
                     AHWLTEADNALNSEWVSHGAIWNNPPYSNIRPWVEKAAEQCIQQRQTVVMLVPEDMSV
                     GWFSKALESVDEVRIITDGRINFIEPSTGLEKKGNSKGSMLLIWRPFISPRRMFTTVS
                     KAALMAIGQGVRRAA"
     gene            7382..8226
                     /locus_tag="IRB70_001994"
                     /pseudo
     CDS             7382..8226
                     /locus_tag="IRB70_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000611488.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase family
                     protein"
     gene            8223..8399
                     /locus_tag="IRB70_001995"
     CDS             8223..8399
                     /locus_tag="IRB70_001995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NinE family protein"
                     /protein_id="HBC0631911.1"
                     /translation="MRRQRRSITDIICENCKYLPTKRSRNKRKPIPKESDVKTFNYTA
                     HLWDIRWLRHRARK"
     gene            8402..8761
                     /locus_tag="IRB70_001996"
     CDS             8402..8761
                     /locus_tag="IRB70_001996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000386647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2591 family protein"
                     /protein_id="HBC0631912.1"
                     /translation="MDYSQLSDFEINVAVFEAIHNGSPDYKEGENGDMVFVSFEGDIV
                     NGDAVEVEVERGSFNPCANPADAWPIIEKYRISIINLDEDEWGARGVAYCKSKRAIHE
                     NPLRAAMIVFLMMQRIQ"
     gene            8761..8937
                     /locus_tag="IRB70_001997"
     CDS             8761..8937
                     /locus_tag="IRB70_001997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001555369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein ninF"
                     /protein_id="HBC0631913.1"
                     /translation="MLSPSQSLQYQKESVERALTCANCGQKLHVLEVHVCEHCCAELM
                     SDPNSSMHEEEDDE"
     gene            8930..9655
                     /locus_tag="IRB70_001998"
     CDS             8930..9655
                     /locus_tag="IRB70_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor KilAC domain-containing
                     protein"
                     /protein_id="HBC0631914.1"
                     /translation="MNELINGNAIKMTSIEIAELVESRHSNVKVSIDRLVKRGVIKPP
                     ALQYTNIINDLCVITGKRDFYVFEGEQGKRDSIIVVAQLSPEFTARLVDRWRELEETA
                     VNIPKTLPEALRLAADLAEQKMQLENQLAIAAPKVEFADRVGEASGILIGNFAKVVGI
                     GQNKLFAWMRDHKILIASGSRHNVPMQEYMDRGYFTVKETAVNTNHGIQISFTTKITG
                     RGQQWLTRKLLDNGMLKVTGEAA"
     gene            9655..9945
                     /locus_tag="IRB70_001999"
     CDS             9655..9945
                     /locus_tag="IRB70_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HBC0631915.1"
                     /translation="MANLRKEARGRECQVRIYGICNDNPETTVLAHYRMAGICGTGMK
                     PDDLIGAWACSACHDEIDRRTMILDNKDARLYHLEGVIRTQAILLKEGKIKS"
     gene            9942..10337
                     /locus_tag="IRB70_002000"
     CDS             9942..10337
                     /locus_tag="IRB70_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015968599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBC0631916.1"
                     /translation="MKTYRIKLPWPPSNNRYWRHSRGTHYISDWGKRYRKEVIELIQQ
                     QQLDIKITPRIRITIHAAPPDNRKRDLDNLPKAVFDALTSAGFWLDDGQIDDMRVKRY
                     QAIKGGMLVLVVTETCGSLPMITELLEAA"
     gene            10334..10540
                     /locus_tag="IRB70_002001"
     CDS             10334..10540
                     /locus_tag="IRB70_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001601990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage NinH family protein"
                     /protein_id="HBC0631917.1"
                     /translation="MTFSVKTIPDMLVEAYGNQTEVARRLKCSRGTVRKYVDDKDGKK
                     HAIVNDVLMVHRGWSERDALLRKN"
     gene            10518..11189
                     /locus_tag="IRB70_002002"
     CDS             10518..11189
                     /locus_tag="IRB70_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001716779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBC0631918.1"
                     /translation="MRYYEKIDGSKYRNIWVVGDLHGCYTNLMNKLDTIGFDNKKDLL
                     ISVGDLVDRGTENVECLELITFPWFRAVRGNHEHMMIDGLSERGNVNHWLLNGGGWFF
                     NLDYDKEILAKALSHKAEELPLIIELVSKGKKYVICHADYPCDEYEFGKPVDHQQVIW
                     NRERIGNSQDGIVKEIKGADTFIFGHTPAVKPLKFANQMYIDTGAVFCGNLTLIQVQG
                     EGAWA"
     gene            11180..11668
                     /locus_tag="IRB70_002003"
     CDS             11180..11668
                     /locus_tag="IRB70_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015973887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator"
                     /protein_id="HBC0631919.1"
                     /translation="MGIRELNLTKEQHEWLNGWLELWGAWVYSGRLEKRMSSVIAKFM
                     ESVEPGRVMTRPMCNDDDGMLISQVVDSVMCIDKKAFGILLSYYAHGSSKHAIASYYH
                     CVARPRKMLCRGGGRIQKPSLATCRREVDEILNASLFMIYPVLDSAFKNRKRVEKIKH
                     VA"
     gene            12206..12529
                     /locus_tag="IRB70_002004"
     CDS             12206..12529
                     /locus_tag="IRB70_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin, lambda family"
                     /protein_id="HBC0631920.1"
                     /translation="MKMPEKHDLLAAILAAKEQGIGAILAFAMAYLRGRYNGGAFTKT
                     VIDATMCAIIAWFIRDLLDFAGLSSNLAYITSVFIGYIGTDSIGSLIKRFAAKKAGIE
                     DGGNQ"
     gene            12513..12989
                     /locus_tag="IRB70_002005"
     CDS             12513..12989
                     /locus_tag="IRB70_002005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family protein"
                     /protein_id="HBC0631921.1"
                     /translation="MVEINNQRKAFLDMLAWSEGTDNGRQKTRNHGYDVIVGGELFTD
                     YSDHPRKLVTLNPKLKSTAAGRYQLLSRWWDAYRKQLGLKDFSPKSQDAVALQQIKER
                     GALPMIDHGDIRQAIDRCSNIWASLPGAGYGQFEHKADSLIAKFKEAGGTVREIEV"
     gene            12986..13444
                     /locus_tag="IRB70_002006"
     CDS             12986..13444
                     /locus_tag="IRB70_002006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009453323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HBC0631922.1"
                     /translation="MSRVTAIISALVICIIVCLSWAVNHYRDNAIAYKEQRDNKASEL
                     EKANATIADMRKRQRDVAELDARYTKELADANATIESLRADVSAGRKRLQVAATCAKS
                     TTGAGGMGDGESPGLTADAELNYYRLRSGIDKITAQVNYLQEYIRTQCLK"
     gene            13650..14168
                     /locus_tag="IRB70_002007"
     CDS             13650..14168
                     /locus_tag="IRB70_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBC0631923.1"
                     /translation="MNNPSVIPAFDFREMVTTLDNNIITTSLKVADYFGKRHKDVLRA
                     IRNLKCSDDFTQRNFAPIDFIDKNGDVQPMYNITRDGCMMLVMGFTGKTAAAVKECYI
                     NAFNWMAEQLNRRMAMGEELQHRYAIKETRSKLKGTIGSRLMNERKKEKRVLELEHEH
                     IMQVTQPELLIG"
     gene            14228..14968
                     /locus_tag="IRB70_002008"
     CDS             14228..14968
                     /locus_tag="IRB70_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631924.1"
                     /translation="MAKPDWGALQHQFLAEHAKTGISPKDWCAAQGLNYSSAKRYIKV
                     TTYGANSQKKTANKSANSQKEKGGVSKNGEVKKNQPDTGAHSKSPETKPIRGSRTAPP
                     TNAFQPGNQNALKHGGYGRRMLLSDAITEDAKMLTLDDELFWLRAASLTAAENIGRWQ
                     TELETAASEQAKDLHDLISQAQKAMHRNTARIESLEYTKAAIIKQRVDAAYREAATEK
                     VELEIDVLKDGDKDNAIVVHNSLPIPGR"
     gene            14972..16303
                     /locus_tag="IRB70_002009"
     CDS             14972..16303
                     /locus_tag="IRB70_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase family protein"
                     /protein_id="HBC0631925.1"
                     /translation="MADIYLPTLHNGQLTVWSDSWDHQLNAVRCGRRWGKTFMLSSAA
                     VTYATSQFRRPGMDIELGGRVGIFTAEYRQYQEIYDKLEEILLPLKKSFSRQEKRLLL
                     KNGGKIDFWVTNDNKLAGRGREYEIILIDEAAFTKSPEMLKEIWPKSIKPTLLTTKGR
                     AYVFSTPDGVDEENFFYAICHNKDLGFHEHHAPTSSNPFVPPEELEKERQNNDPRVFR
                     QEFLAEFVDWSAASLFDVRKWFEGENQDQPVDYPEMCQAVFAVMDTAVKGGTEHDGTA
                     VVYYAVDTRPGIQRLTILDWDVVQIDGALLEEWIPSVFTRLNELSGQCVAVNGSLGVF
                     IEDASMGSILLQKGESLGWPVNKIESALTSKGKDERAIMASGYHYRGLAKISRYAYEK
                     TAVFKGETANHLHKQVSRFHLADKNAHKRADDLLDDYTYGLIIAFGSGDAL"
     gene            16315..17730
                     /locus_tag="IRB70_002010"
     CDS             16315..17730
                     /locus_tag="IRB70_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017898842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1073 domain-containing protein"
                     /protein_id="HBC0631926.1"
                     /translation="MNEDDIAIGSCSPELITLLDSDDIQPGMSAGYQTCKTIYLFHPL
                     GGKMVDRPIKMAMNESRTVHISQAYGIEQRLRDAFEREWKALGADKHIANAARISRIY
                     GVSAIAMLVDNQEPSSAVDYRTLYKHNVTFNILDPLNTAGSIVLNQDPNAQDFQKVDG
                     IRVAGKPYHKSRCVVQQNEDPIYLAYNSAAFGFTGRSVYQRALFPLKSFIQTMRTDDM
                     VSVKGGLLVTKIQGPSSVVNNMMQKLSGIKRMMLKRGKTGEVLQIGANDSIESIDLSN
                     LEKPLDSSRNHILENIAAAADMPAIILNSETFAQGFGEGTEDARSVAVYIDNIREWLE
                     PLYDYFIRICQYRAWSIEFFNSLRADFPELKNTYSLYFSSWINNFEYRWPSSLKEPES
                     EKVKVDEIRFKAIVSMLEVLLPQVNTDDENRALLIEWAQTNANANESLFPQRLDLDID
                     SLKANRPEQPRDEEPGGGMML"
     gene            17727..18548
                     /locus_tag="IRB70_002011"
     CDS             17727..18548
                     /locus_tag="IRB70_002011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000847583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631927.1"
                     /translation="MKTFTRTVREAVKFFLRNGYTSRQELEQWQAIIRQAAESETDDD
                     YMSMVSDRLRKTYDLQVSKAGALERHKGLSRFTLNYMEPKLRSELDRRILASADLIKL
                     NRKKAIDTTLSRFSGWASSIPSADSIALTGIQGTMRETAAHIQKAAERVDYEARRVMI
                     DQSHKLIANIDNIIATGNNAIAAEWHSHWRQPGYDYREDHKERDKLIYLIRGNWAQKN
                     GYVKAGPAGYLDEITQPGEEVFCRCYVTYLYNLRSIPEDMLTKKGRKFQESMKAA"
     gene            18561..20174
                     /locus_tag="IRB70_002012"
     CDS             18561..20174
                     /locus_tag="IRB70_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000964072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBC0631928.1"
                     /translation="MAIFGSGIMFRQGKFVFLIQRSDDGTWCQPGGTIEPGELAIDAA
                     RREVLEETGYQYDGPLTPHSVHGDYLTYRADVPEQFEAKINDESLAAGWFHIEDLPKP
                     LHQPFAEMLAQQALNETDVAALIADGTLSSPQYFYNMWMFAIRVTGTGVTWRSADQEM
                     TFRNPDDYLTPEFLQRVAGVPLIWLHPEKRTLDSDEFSKRVIGTLTNAWVADKGEVWA
                     VARVYDAEAAEIMATRQLSTSPTVKFSEVAQSIIVDGQPLLVEPSPELLDHVAICEQG
                     VWDKLLAPTGVKSDSIPEEAEKMDEEKIVALINKAIDARLAKADEEKEAKAKADAEEA
                     AKKEKADAEDKEAEEAKAKADAEEKAAKEKADAEAKEKADAEEAEKMAKEKADSQILQ
                     EIAELRSRIPTELSDEERNEVAEAQVKADSVFSSFGKRAPIPLSGEKPMAYRRRLMIQ
                     LQEHSPDYKAVDLSAIADSQLLSTAEKHIYADAQKAASLSVGPGMLREIKRADATGRQ
                     ISTFEGDPAVTWAPFQSGKRQVTSFNNQA"
     gene            20190..21050
                     /locus_tag="IRB70_002013"
     CDS             20190..21050
                     /locus_tag="IRB70_002013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000002315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631929.1"
                     /translation="MANLSLNPMATTNAAGSFGVQSDGFIQGVALDDPANRFNLASGT
                     VAATETKPLWGGLPVAELLPGVNSSPRGSTIRRAASLAELEGFTVFNQAHNGLTTPQS
                     PVPLYASGMSVSFYRLGSNMRVPLKASAQVVALGTAGASVKTPLAWDFVNNQVTTAAA
                     AAFAGADIDTTAVTYSNGVATATTASAHGLTAGQYVKISGVAPTAYNGTVVVLSVPST
                     TTFTYAPASAPGGSATTQGTIGAVAQADITLPVKVISIESGNSKTVSYDSATGFLTWN
                     NTDSCALVLL"
     gene            21064..22095
                     /locus_tag="IRB70_002014"
     CDS             21064..22095
                     /locus_tag="IRB70_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015406010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2184 domain-containing protein"
                     /protein_id="HBC0631930.1"
                     /translation="MAAITPSYTIVNPSYIAPELIIGYQQASGAFETIASGNPQVRLG
                     VGDQYVYMRRLDIRTQVTSSQSGNANQLPSVALEARMISTPTYLFRCRGIYDHHDTAA
                     AGNWNVALPEAQRLGMRQGIFQQLRSALLYGMNPAGGEGLLNTAGATTETLPQDSNSN
                     TTVLTYDHGQMAVYLLGHVQAALTRTMQLGRQQRVVILGPQRVLGAMEIQQIVQLTSY
                     QRPGGGTDTVGGTVKEVLRGANVQVDWVYDDTLIGAGAGGTDAVVITIPEVEVPMVNS
                     TVNTNEFAKLSPSLAANALMFTDMAAPMEIPTPIPGGAIDVLSEMRSTAGWAVRPEAI
                     TILSMKYSD"
     gene            22168..22650
                     /locus_tag="IRB70_002015"
     CDS             22168..22650
                     /locus_tag="IRB70_002015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017898838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631931.1"
                     /translation="MKLYIANTTKQRHIFTFRQLETGRLRQIPIEHGSQMLVLDGSTE
                     EVEAVIQHHQVYGLVDSTKIDQSQAFVGLCYSINKPVSASVIEKTIRDNDGHLTRGAH
                     NRRQASVAALDNTLRESGIGYEGDMEFSAEQAKGRDDHSDDPTINEKIVTPKAGSKKK
                     "
     gene            22647..23075
                     /locus_tag="IRB70_002016"
     CDS             22647..23075
                     /locus_tag="IRB70_002016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000213588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631932.1"
                     /translation="MTTSLSGFIEFVRSDMGITPDQVPDDSPSFSLAYGGAIEWVNPD
                     IACVMPNMYSIAVYNLGASFLINYGTEAVFAEFRKQYGLNDFKAGVITGAGDNSTSAQ
                     RLVPDFFKDLSLADLQMLQDPWGRRYLMFAQQFGSLWGLT"
     gene            23072..23506
                     /locus_tag="IRB70_002017"
     CDS             23072..23506
                     /locus_tag="IRB70_002017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631933.1"
                     /translation="MITFHLGVIDIPYEDEDTTTGSVAEELEARYQIMQTFFDRYGND
                     IAELMSKDLAAALENMFAGAPPAKDPLAESMSKVHDLFVGFLDNTEMNGLPGVPTRRA
                     LEGISKRFKGKKGPPRPSFIDTGTYQAAMRAWVSGVLNAFPE"
     gene            23490..24428
                     /locus_tag="IRB70_002018"
     CDS             23490..24428
                     /locus_tag="IRB70_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001139498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631934.1"
                     /translation="MPSLSELQNAKTELNATLTQGLDDLSRFQVVTFTKYIRKVLPLD
                     GFVFWVKASVLSDDPNNEPDTVDVKGYLHLTTETIQDDEQLYDRNVVTFTAQADIDPF
                     NDIGSEVLYIGEFFGVQFSFSRRTGLNEPANLYHYTGEAIFPHMRSQIINSADDIDLS
                     DVVVSSSLPIWLALNQYMPMFPAMLSTQNLSPPYATVKCSNTSPIAGAFYLDEKQNQY
                     QLVSEDVTLSVTGLRNASIEDFVRYVQDYTTGDAPEMGIMNIPVVQDERVTQNELNII
                     AMRKTIKFKINYYQQRMRNLARQLITSAIPSIDPEK"
     gene            24433..25827
                     /locus_tag="IRB70_002019"
     CDS             24433..25827
                     /locus_tag="IRB70_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010835740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631935.1"
                     /translation="MAIVNINVSVTNPPKPSQLLKSGAMISMGGTTLNAGEYQLLTSE
                     TDLADILAPAKTISTLAWATGVVTVTLAAAHGWTNGSQVPVIISGATPAGYNGAYTAT
                     VTGANTFTYPLTTNPGTATAMGTVKTVVQTEISQMNTSFWAQGKTRAVYVLELGDVSM
                     EEAVAALTTFIAEDVALGNTYQKFFSYLVPREWDSVDEFKTLTGLYTSPGSLVYFFVT
                     TTIATYQDWVATKNKTVFAGVEAPDIPASEFSMAGPFQSSLANDPGSSNMVPPMSYRF
                     MYGLTEYPLEGNSALLKSLQDSNINYIGTGAEGGLSNKVLFTGRMLDGNPFNYWYSVA
                     WTAINLELDLANEIISGSNTTVNPLYYEQKGIDRLQRRALKTMRNGISYGLILGRVID
                     TQLTQEDFNTEYDKGTYAGNAVINAVPFSNYNSLNPSDYQEGKYNGLSAVMTPRRGFE
                     SITFNVNVTNFVGA"
     gene            25831..26268
                     /locus_tag="IRB70_002020"
     CDS             25831..26268
                     /locus_tag="IRB70_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631936.1"
                     /translation="MANPLVPQGFLNRVRGALSVTDTPALNVSASYLAKDGISLRPDG
                     PATDIIPTMTGTVGSQAPYQQVTLTVHLLKTQGLGESYRQRFLTDTSLGEIVVTPDAT
                     TFGNITLLNCYLVNFNELAFSGMDPAFVVTISGYMVTNDNMWV"
     gene            26272..26844
                     /locus_tag="IRB70_002021"
     CDS             26272..26844
                     /locus_tag="IRB70_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017898832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631937.1"
                     /translation="MKIDKKLNLVTNVTREDGSIVYLHVTPFPYEVVEEHCILLGNLF
                     TKFISQVGGLGAARIAAMMLRQSLKAEIDNGRTGPNIVDEIQRLTVVIHNVGGQWKTT
                     PLEVAFKQGIIDPDEYREVEGEVVFFMVSSAIQKANLIAPTVGTVIKMYDGQLTSSSG
                     TAFRDSLQTSKPDTDIPTQNAQPETSFIPS"
     gene            26968..28872
                     /locus_tag="IRB70_002022"
     CDS             26968..28872
                     /locus_tag="IRB70_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004884197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBC0631938.1"
                     /translation="MVAKSIVDIDVNDDKFVAFMERFREYQSALDDLPEAWRVAAVGI
                     GESSKQTEKAKGEAKELGAEFNAVAEAILTINSGIDRLNANLEDSKKKQDEFNKSTRS
                     AKGFLSDATKDAKSLAGHIKEATASLLSWGGIVGIFTGVLGVGGLFGINRLAATTGAQ
                     RFTSLGLGTSIGALDSTAINYQKALGNPAGTLGAIRDSQMDLSKRWTFQAMGINNPDQ
                     DPAKLLPQMIRNARDIFVQNGSTLQGAQAHGLTNFFTLDDLNRFKNMSDEEITAMEKR
                     AQQDARMLQITDQQARQWQDFNVQLDYSSQSIRNTFVRGLGPLTPQLSKLSDALSGAI
                     DTVLKSPELGKWIDALAGGIERFGNYLASPTFKSDVESFMSGVERLGRVIMKVLGWLD
                     GGSSAMDDIKSGSSFLNNDVQTDAGGNHFVKGGLSDPNTPAASKWLARHLYSLTGTAP
                     SEYDQYFLDAAKKYNVDPRWLKAIAAGESSWDQNAQGPVTRSGKRALGLMQIMPDNFQ
                     PGEKPFDPRDNIMAGARVFSWAMQSANGDIDEALRYYNGGSRRGSAENRAYPGRIREK
                     YAAMYGAPKNNDASGVDSSEIAKNTSKTNQLLQQIVDGKGGRGGSGDVVIYNNTGGNA
                     VVTSAQLGAR"
     gene            28872..29582
                     /locus_tag="IRB70_002023"
     CDS             28872..29582
                     /locus_tag="IRB70_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000507079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631939.1"
                     /translation="MGFTREMYKLGFEISPVILCGGIAQAIPGGMLPIVALTQSASFV
                     TGLLGGAINLTDLDKYFCHWRPVQGATMVDYEIARYPFANQVVAANALLAQPLRVSLV
                     MEAPVNENSGAMTKLVTMSALQSVLQAHSNLGGTFIVATPSVIYSNCILRVVRDITSG
                     NDPLPQRSWIWDFEQPLITDNGAEQAVNNFLNKIGAGDMVTDPSWTNTANALGNTPLG
                     SSVSEAITGLLGKLGVGP"
     gene            29854..30891
                     /locus_tag="IRB70_002024"
     CDS             29854..30891
                     /locus_tag="IRB70_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001271126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631940.1"
                     /translation="MRYYDIEITIPAEGASPERTIKYSSHKNGVYNPGALMIEFDILR
                     YGESTPQGETHLTIWGIGPKEMQQARQNFFGKKIKIFLGMKDGLPLAGKVTAPKLVLD
                     GVINQVFGNWQGIELRLDFIIVVGPVQNVPNNKPVPLPLTFDWKEGQKLSVALTQCFM
                     NIRGYTFNINISDRLILNHYRGLFCDDIVTLAKDLNAFSRSRIRDSGYSGVEIAIVNG
                     NEIRVWDNDYDNHPDKTSVSSAVARSNSPTQIDFKDLIGQPTWVAFNTISMACVMRGD
                     IQVGDHILMPKKSTPLIKASSYSQYREDSAFTGDFIVNSVRLLGNSRQPTAEAWVTII
                     EASPFIKAGNA"
     gene            30888..31604
                     /locus_tag="IRB70_002025"
     CDS             30888..31604
                     /locus_tag="IRB70_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003833583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631941.1"
                     /translation="MSIDNKLNFASSMNRFTERKIENALQKSGKVLPASVVKQTGNMI
                     TVSFELRDIPYVLPQVTIPLFGPQYIRYPMQPGDKGIVIPADTYIGGVSGQGGGIADM
                     TPPANLSALVFLPISNTEWQGVDGQVVTVYGPEGVTLRDSGSNTTFLLKPDSIAISTP
                     DSFTVTVGGTVFSLTGSKWSLSGQAGHLQDSVASTSPAIMHAGWQSLLTWLNSHEHSN
                     GNDGNDTGGPTSTFNGSITE"
     gene            31601..31933
                     /locus_tag="IRB70_002026"
     CDS             31601..31933
                     /locus_tag="IRB70_002026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631942.1"
                     /translation="MRTYGRNSEGKWVLVETDENGFNDSVYLTTLIQNLKLAPQESPF
                     YANNGIPAAGSVIQQILPTYYVNRIQKQFSQYFSSLQIALISDDPPVYNISAITNAGS
                     KIITQVAV"
     gene            31930..33348
                     /locus_tag="IRB70_002027"
     CDS             31930..33348
                     /locus_tag="IRB70_002027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBC0631943.1"
                     /translation="MSDLPVSYTSAGPVPLTPEELRAQLVSQAIALSPGLTTDLPGSL
                     IEDVASTDVGALIVCDQARVDLINSVGPLKANLAMLELLAQQAGIPGQKTAGTTTVPV
                     QFSGPAGFVIPQGFIVSDGTYTYSVSDATIISSSGVSASVSCEGTETGTWAVPVNTVN
                     QIISSLPSDVTITCTNPIAGTPGADPETNYQFRDRVWQAQMATVQGYPGFIRQHLTSL
                     DNVQARLVSVIQDGDKWIVMCAGGDIYDIAGALYKSAGDISRLKGCSLNVTGITNANP
                     GVVSTDLTHGYTDGQVIRITGVTGMTGINDVPLTVTVLSPHTFSIGIDTTSSGTWGGG
                     GEVTPNVRNNTVTVNDWPDNYVIPFVTPLLQRVTVTYQWGTESVNYLTDATVASLVSA
                     PTIQYVNGIFAGKPLNVNNLKDAFLQAINSTIDMGLISTLNVVVTINGVITPPDAGTN
                     IISGDKFSYFYIASDGVIVTGA"
     gene            33350..34054
                     /locus_tag="IRB70_002028"
     CDS             33350..34054
                     /locus_tag="IRB70_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631944.1"
                     /translation="MLDDIIRSYMYTQYNDDDNLRAFFTAYNSMAQGIYDWMVNANLP
                     IFIGDYNTGDQLRWIAHGIYGVLPPVISSSDQQEIGPYNTFEFNQLAFNEYRVIDQSN
                     QVVVSDDLFKRIMTWNFYKGDGFYFSIPWIKRRILRFLLGVNGTDILNDQRWSISIQF
                     VDGGIVISIYKGRRKFTRSAIYNASAYNSRKYNQKDTAFVITEDFEFAIFFKQAMDSG
                     LLHMPFYQSISVEIID"
     gene            34113..34790
                     /locus_tag="IRB70_002029"
     CDS             34113..34790
                     /locus_tag="IRB70_002029"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631945.1"
                     /translation="MKTSIMLAFLSVSLCAGSSFAASFDCNKSKNFAEKTICSDKKLS
                     EDDEVLAKVYNLAKKVAHNKNGFDRLTKDLWDSRDLCTDYKCINDWYDTVFVAYDSVI
                     KTNASDEVLNNIQKKYDESITQKPAISNGAKNKKEAKDYSLYDSKDRAAPVEHNAILY
                     KDTPEAFEFIDTLVGFVRQSSYKCDSVSSFIPMVSSNGFTLACNKFSYKYEIKNNGGN
                     VSVSVDN"
     gene            34884..35294
                     /locus_tag="IRB70_002030"
                     /pseudo
     CDS             34884..35294
                     /locus_tag="IRB70_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704142.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GDSL family lipase"
     gene            35784..37019
                     /locus_tag="IRB70_002031"
     CDS             35784..37019
                     /locus_tag="IRB70_002031"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631946.1"
                     /translation="MSVTQTWRTGIPTPGVLRNYPPNPLYVDSVNGSPSGTGSVDNPV
                     NTLSLALGLCAGLPDYEIKISAPENSPLRQEVIFDTSLDVTLSGVDSEPWYTFGSEKH
                     ISGWTQSGQIWRKTLGYTSVLQAVVTTMAETVGDRDDFFFKLVQNTATPTTPAAGEYG
                     YSGGVIYVRLPDDSSPNLHTIEISRRNFGVGTIGFGLLTVNDCVARYCMINGISCGQS
                     TQPAGTGYLTVNNSLIEYCANGGVGGTGRNELIICNNVKAYRISNDGFNQHAPTGGQG
                     KMILNGCDGSYNGDKAGQSAQGASNHETTTMILNGGTFNFNVSGGMVVIDNARCDIHG
                     DTQYGPVMMNGNMRLGNTAGTIANQGGCAWLNNSVGTVTGSVTVENGGGVGVRRDSGA
                     VVDGITTIHSINNALPDIL"
     gene            37307..37546
                     /locus_tag="IRB70_002032"
     CDS             37307..37546
                     /locus_tag="IRB70_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012542576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631947.1"
                     /translation="MLRQSDIAAAFRESVLRSSKGFQYLHPQDFVTALRRRGIHFSEV
                     EANSWIAREQTYFVDKTPDHSENRLWMMANMGRVI"
     gene            37546..37863
                     /locus_tag="IRB70_002033"
     CDS             37546..37863
                     /locus_tag="IRB70_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631948.1"
                     /translation="MGFPSPASDYVEQRLSVNSICNVGPNTLVFEQSGGYVVLDISMK
                     PKQGSQVLIRHGGGTELATLRGKSLITEDGEAIEGEALDDVTVIGVVTFTICDVRSDN
                     SII"
     gene            37875..38906
                     /locus_tag="IRB70_002034"
     CDS             37875..38906
                     /locus_tag="IRB70_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631949.1"
                     /translation="MALKLLANNNAKSVLAAGISASATVITVGTGAGALFPSPVSGQS
                     YFKLTITDAATKTISEIMHVTSVSGDVMTVIRGQEGTTARVWSTNDIVANLMTAGSLL
                     SFLQISNNLSEIKDAGEDAVNEARYNLGIADSSGFVGRSLGAPKAFYANGTYTRSPLA
                     RYAKVTLTGAGGGGGGCQASNNTETFSGAGGGAGATIVVWVDLSAASSYAITVGKGGK
                     GGVGAVSGSDGGTTSFASLFSAPGGKGGVKSGVSNTAGGAGGTAAAGDIRINGGTGSD
                     GQTGSSLLTGNGGASYFGGGGRAGSQAGIAGAAPGSGGGGAYDLGFTSTAYTGGDGAD
                     GILILEEFA"
     gene            complement(38911..40071)
                     /gene="intS"
                     /locus_tag="IRB70_002035"
     CDS             complement(38911..40071)
                     /gene="intS"
                     /locus_tag="IRB70_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000958667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage integrase IntS"
                     /protein_id="HBC0631950.1"
                     /translation="MLTVKQIEAAKPKEKPYRLLDGNGLYLYVPVSGKKVWQLRYKID
                     GKEKILTVGKYPLMTLQEARDKAWTARKDISVGIDPVKAKKASSNNNSFSAIYKEWYE
                     HKKQVWSVGYATELAKMFDDDILPIIGGLEIQDIEPMQLLEVIRRFEDRGAMERANKA
                     RRRCGEVFRYAIVTGRAKYNPAPDLADAMKGYRKKNFPFLPADQIPAFNKALATFSGS
                     IVSLIATKVLRYTALRTKELRSMQWKNVDFENRIITIDASVMKGRKIHVVPMSDQVVE
                     LLTTLSSITKPVSEFVFAGRNDKKKPICENAVLLVIKQIGYEGLESGHGFRHEFSTIM
                     NEHEWPADAIEVQLAHANGGSVRGIYNHAQYLDKRREMMQWWADYIDGRAGE"
     gene            complement(40233..40307)
                     /locus_tag="IRB70_002036"
     tRNA            complement(40233..40307)
                     /locus_tag="IRB70_002036"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(40272..40274),aa:Arg,seq:cct)
     gene            complement(40383..41315)
                     /locus_tag="IRB70_002037"
     CDS             complement(40383..41315)
                     /locus_tag="IRB70_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBC0631951.1"
                     /translation="MDNDKIDQHSDEIEVESEEKERGKKIEIDEDRLPSRAMAIHEHI
                     RQDGEKELERDAMALLWSAIAAGLSMGASLLAKGIFHVELEGVPGSFLLENLGYTFGF
                     IIVIMARQQLFTENTVTAVLPVMQKPTMSNVGLLMRLWGVVLLGNILGTGIAAWAFEY
                     MPIFNEETRDAFVKIGMDVMKNTPSEMFANAIISGWLIATMVWMFPAAGAAKIVVIIL
                     MTWLIALGDTTHIVVGSVEILYLVFNGTLHWSDFIWPFALPTLAGNICGGTFIFALMS
                     HAQIRNDMSNKRKAEARQKAERAENIKKNDKNPA"
     gene            41609..42364
                     /gene="mlaA"
                     /locus_tag="IRB70_002038"
     CDS             41609..42364
                     /gene="mlaA"
                     /locus_tag="IRB70_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding lipoprotein MlaA"
                     /protein_id="HBC0631952.1"
                     /translation="MKLRLSALALGTTLLVGCASSGTDQQGRSDPLEGFNRTMYNFNF
                     NVLDPYIVRPVAVAWRDYVPQPARNGLSNFTGNLEEPAVMVNYFLQGDPYQGMVHFTR
                     FFLNTILGMGGFIDVAGMANPKLQRTEPHRFGSTLGHYGVGYGPYVQLPFYGSFTLRD
                     DGGDMADGLYPVLSWLTWPMSVGKWTLEGIETRAQLLDSDGLLRQSSDPYIMVREAYF
                     QRHDFIANGGELKPQENPNAQAIQDDLKDIDSE"
BASE COUNT        10908 a        10442 c        11114 g         9927 t
ORIGIN      
        1 gacgaatgaa ttcttcgtct gaccagttat ctgtaaaact catttcctgc gataccacgg
       61 aaggttgata gctgatttca tcgctttatt tgcttcaagc cacatttttg aatcaccaat
      121 aaatctggct attactgctt tgttttgtgc cgcacgaagc atctggtgat tgatggctat
      181 ttcattgcgc ataacgcctc cagttgtttc tttgctgctc tgattaattg tttaactcgg
      241 cgtgataatt cagattcgtg cgggtagaaa gcggacatga cgccgctacc cgcgagctga
      301 aagtgcatca tgggtaactc cttatatttg attgcataac gaaaacgcct cgaataaagc
      361 gttattggta tgcatataaa aaggccctca cactggaggg caaagaagat ttccaataat
      421 cagaacaagt cagctcctgt ttagttacga gcgacattgc tccgtgtatt cactcgttgg
      481 aatgaataca cagtgcagtg tttattctgt tgtttatgcc aaaagtaaag gccgactatg
      541 cggcctcgga aggaagtcca atcatcttat tcaaatcttc tacccgtaaa gcaggaagtg
      601 ctgtacttgc tttatctgct tcttctggta gcaattcttt gctttcaggc caaacttcaa
      661 taagtcgctt aactgttgtg actgagttca aagcagccca tacatttgat tcgatatcct
      721 ttttcttggc ttcaagtttt tgttgcaatg cgcagatttc atcaaacctt tttgttattt
      781 cgtgttctgc gctaaacatg catttatctt tggtcggagt agggagcaat atatcttcgc
      841 cgttgccgtc tttcccatat gaatgccatc caacccttct gccagataca gtcagataaa
      901 ttgaagtaga actaacatcg tatgagtaaa atgaacatcc catcttttca agttcttcac
      961 ttatagctac caacttggat gataactgat ccacttcctc agttttcttt ttaccgccaa
     1021 acgcaataac tctggcgtca agtgcaagct ggttctttaa ctttgttact tcttcaagtt
     1081 cagtgaaaac cccagactta attaaagcgt tacgagcgat ttcctctttc attctcgtag
     1141 ttaagcggat tgatgacata ttaattcctc tcaaataagt ggcttgctgc ctaatttcat
     1201 tttctggcga ccaacacaag tcacacccat ttcactgcgt ggcttgctgt accatgtgcg
     1261 ctgattcttg cgttcaatac gttgcaggtt gctttcaatc tgttcgtggt attcagccag
     1321 cactgtaagg tctatgggat tcagtgcgct ttctactcgt gatttcggtt tgcgattcag
     1381 cgagagaata gggcggttaa ctggctttgc gcttacccca accagcaggg gatttgctgc
     1441 tttccattga gcctgtttct ctgcgcgacg ttcgcggcgg cgtgcttgtg catccatctg
     1501 gattctcctg tcagttagct ttggtgattg gatggccggc gctgaacccc ggcttactgg
     1561 ttagagcgcc cgcactacca gtgacgctgt cttgaggcgc agattggtta ctgcttgcca
     1621 tgagcgctgt ttatacattg gtcgagcatc agcctgctca ttcatccaat cccaaagcct
     1681 tctgctttga atgctgccct tcttcagggc ttaattttta agagcatcac cttcatgtgg
     1741 gttagtgcgt cctgctgatg tgtttagtat caccgctagt ggtatttgtg tcaacaccgc
     1801 cagagataat ttatcaccgc agatggttat ctgtatgttt tttatataga tttatttttt
     1861 gcagggttgt gtggcttggg aggtgatcga gagatcagaa ttgcgttgtt tagtgagttg
     1921 cacctattaa ttttaaaata aatacaattg gttatgtgtt tttaggtggg gcgatcgtga
     1981 ggcaaagaaa acccggctcg gtggccgggt tgatgggatt atcgtttatt tctttgatgt
     2041 ttctttgcag actcagcttg agtgtttcca tacctgcgtt taccgctatt gttttttcct
     2101 ctaggcttgc ctttttttcg atcttcccac cagtcaggtg ccgggtctgg ctcaacatgt
     2161 aaagcatcgg caagtcctga tatcaagctg tatgactgaa ctccatcaat gtgctctgac
     2221 agtgatgggg taacattctg tcttagtgga tcaagaataa aatcaatacc tttaattctg
     2281 gcgtgtttgg cggcaggcac aaagtctgag tccccagcaa caaggacaat tacatcaaca
     2341 agtttttcat aagctaaagt cgtgatatcc atccctagct tgatatcaac ttgtttttgt
     2401 ttgatgtcat agtaaaaatc atcatttgtc agttcatccc attttttcgt tcctttcatc
     2461 agagcatcaa gggagaatgt agttagttgc catcgcttat tatcaacaag attccctaat
     2521 cttaaggctg tttttcgagt ttttcttaac tcttcatgca gctccgttct cagaatatat
     2581 gatttttcga gtttgaaatt cttgcgacca ggcgtcttat tgccaggctc aggaagtgga
     2641 aggcgtgttt gaatgtcgag tggtggacag tcatagaagt aaattctata aagctcaagc
     2701 ggttccctac gttcttgtga ttgacgtttt ccattaagat gggaaagaac cattgaccat
     2761 attactttca ttatgcattg cgcagtcagt tcatgctcgg cgaagtgttt acgatgcgta
     2821 gcatgaacac gctgcatgaa aaaacccgca tcaattaaaa ttgctgcttt cttcataaga
     2881 gtcccaaaaa aatagcccag agccgttatg cagatattaa caattgtctg cgaacggggc
     2941 tgggcttggt ttaattaatc tatgccaagt tgactgtgcc gtcaacataa aacttacttc
     3001 ctatcaccca aacgtctctt caggccactg actagcgata actttcccca caacggaaca
     3061 actctcattg catgggatca ttgggtattg tgggtttagt ggctgtagaa acacctgacc
     3121 gctatccctg atcagtttct tgaaggtaaa ctcatcacca ccaagtctgg ctatacagaa
     3181 atcgcctggc tcaacagcct gctcagggtc aaccagaatt aacatcccgt caggaaagct
     3241 gggcttggat cctgttggtg cggtcatgga attaccttca acctcaagcc agaatgcaga
     3301 gccactggct tttttggttg tgcttaccca tttctccgca tcgcctttgg taaaggttct
     3361 aagctcaggc gagaacatcc cggcctgaac atgagaaaaa acagggtact catactcact
     3421 tctaagtgac ggctgcatac taaccgcttc atacatctcg tagatttctc tggcgattga
     3481 agggctaaac tcttcaacgc taacgttgag aatttttgca agcaatgcgg cgttataagc
     3541 atttaatgca ttgatgccat taaataaagc accaacgcct gactgcccca tccccatctt
     3601 gtctgcgaca gattcctggg ataagccaag ttcatttttc tttttttcat aaatagcttt
     3661 aaggcgacgt gcgtcctcaa gctgctcttg tgttaatggt ttcttttttg cgctcatacg
     3721 ttaaatctat caccgcaagg gataaatatc taacaccgtg cgtgttgact attttacctc
     3781 tggcggtgat aatagttgca tgtactaagg aggttgtatg gaacaacgca taaccctgaa
     3841 agattatgca atgcgctttg ggcaaaccaa gacagctaaa gatctcggcg tatatcaaag
     3901 cgcgatcaac aaggccattc atgcaggccg aaagattttt ttaactataa acgctgatgg
     3961 aagcgtttat gcggaagagg taaagccctt cccgagtaac aaaaaaacaa cagcataaat
     4021 aaccccgctc ttacccatcc ccgccctgaa aaagggcatc caattaaacc acacctatgg
     4081 tgtatgcatt tatttgcata cattcaatca attgttatct aaggaaatac ttacatatgg
     4141 ttcgtgcaaa caaacgcaac gaggcactac gaatcgagag tgcgttgctt aacaaaatcg
     4201 caatgcttgg aactgagaag acagcggaag ctgtgggagt tgataagtcg cagatcagca
     4261 ggtggaagag agactggatt cccaagttct caatgctgct tgctgttctt gaatgggggg
     4321 tcgttgacga cgacatggct cgattggcgc gacaagttgc tgcgattctc accaataaaa
     4381 aacgcccggc ggcaaccgag cgttctgaac aaatccagat ggagttctga ggtcattact
     4441 ggatctatca acaggagtca ttatgacaaa tacagcaaaa atactcaact tcggcagagg
     4501 taactttgcc ggacaggagc gtaatgtggc agatctcgat gatggttacg ccagactatc
     4561 aaatatgctg cttgaggctt attcgggcgc agatctgacc aagcgacagt ttaaagtgct
     4621 gcttgccatt ctgcgtaaaa cctatgggtg gaataaacca atggacagaa tcaccgattc
     4681 tcaacttagc gagattacaa agttacccgt caaacggtgc aatgaagcca agttagaact
     4741 cgtcagaatg aatattatca agcagcaagg cggcatgttt ggaccaaata aaaacatctc
     4801 agaatggtgc atccctcaaa acgagggaaa atcccctaaa acgagggata aaacatccct
     4861 caaattgggg gattgctatc cctcaaaaca gggggacaca aaagacacta ttacaaaaga
     4921 aaaaagaaaa gattattcgt cagagaattc tggcgaatcc tctgaccagc cagaaaacga
     4981 cctttctgtg gtgaaaccgg atgctgcaat tcagagcggc agcaagtggg ggacagcaga
     5041 agacctgacc gccgcagagt ggatgtttga catggtgaag actatcgcac catcagccag
     5101 aaaaccgaat tttgctgggt gggctaacga tatccgcctg atgcgtgaac gtgacggacg
     5161 taaccaccgc gacatgtgcg tgctgttccg ctgggcatgc caggacaact tctggtccgg
     5221 taacgtgctg agcccggcca aactccgcga taagtggacc caactcgaaa tcaaccgtaa
     5281 caagcaacag gcaggcgtga cagccagcaa accaaaactc gacctgacaa acacagactg
     5341 gatttacggg gtggatctat gaaaaacatc gccgcacaga tggttaactt tgaccgtgag
     5401 cagatgcgtc ggatcgccaa caacatgccg gaacagtacg acgaaaagcc gcaggtacag
     5461 caggtagcgc agatcatcaa cggtgtgttc agccagttac tggcaacttt cccggcgagc
     5521 ctggctaacc gtgaccagaa cgaagtgaac gaaatccgtc gccagtgggt tctggctttt
     5581 cgggaaaacg ggatcaccac gatggaacag gttaacgcag gaatgcgcgt agcccgtcgg
     5641 cagaatcgac catttctgcc atcacccggg cagtttgttg catggtgccg ggaagaagca
     5701 tccgttaccg ccggactgcc aaacgtcagc gagctggttg atatggttta cgagtattgc
     5761 cggaagcgag gcctgtatcc ggatgcggag tcttatccgt ggaaatcaaa cgcgcactac
     5821 tggctggtta ccaacctgta tcagaacatg cgggccaatg cgcttactga tgcggaatta
     5881 cgccgtaagg ccgcagatga gcttgtccat atgactgcga gaattaaccg tggtgaggcg
     5941 atccctgaac cagtaaaaca acttcctgtc atgggcggta gacctctaaa tcgtgcacag
     6001 gctctggcga agatcgcaga aatcaaagct aagttcggac tgaaaggagc aagtgtatga
     6061 cgggcaaaga ggcaattatt cattacctgg ggacgcataa tagcttctgt gcgccggacg
     6121 ttgccgcgct aacaggcgca acagtaacca gcataaatca ggccgcggct aaaatggcac
     6181 gggcaggtct tctggttatc gaaggtaagg tctggcgaac ggtgtattac cggtttgcta
     6241 ccaaggaaga acgggaagga aagatgagca cgaacctgat ttttaaggag tgtcgccaga
     6301 gtgccgcgat gaaacgggta ttggcagtat atggagttaa aagatgacca tctacatcac
     6361 tgagctaata acaggcctgc tggtaatcgc aggccttttt atttggggga gagggaagtc
     6421 atgaaaaaac taacctttga aattcgatcc ccagcacatc agcaaaacgc tattcacgcg
     6481 gtacagcaaa tccttccaga cccaaccaaa ccaatcgtag taaccattca ggaacgcaac
     6541 cgcagcttag accagaatcg gaagctttgg gcttgccttg gtgacgtttc gcgtcaggtt
     6601 gaatggcatg gtcgctggct ggatgcagaa agctggaagt gtgtgtttac cgcagcatta
     6661 aagcagcagg acgttgttcc taaccttgcc gggaatggct ttgtggtaat aggccagtca
     6721 accagcagga tgcgtgtaag cgaatttgcg gagctattag agcttataca ggcattcggt
     6781 gcagagcgtg gcgttaagtg gtcagacgaa gcgcgactgg ctctcgaatg gaaagcgcga
     6841 tggggagatc gggctgcatg actatcaaat caaatacgcc agcacacgac aaggactgct
     6901 ggcaaacgcc gctttggctt tttgatgcac tggatattga gtttggattc tggctggatt
     6961 cggcagcgag cgacaaaaat gctctgtgtg ctcactggct aactgaggct gacaacgcgc
     7021 tcaattctga gtgggtaagc cacggtgcaa tctggaataa cccaccgtac agcaatatca
     7081 ggccgtgggt ggaaaaagcc gctgagcagt gcatacaaca gcgacagacg gtagttatgc
     7141 ttgtgccaga ggatatgtca gtcggatggt tcagcaaggc tctggagagt gtcgacgaag
     7201 ttcgcattat cactgatgga cggattaatt ttatcgaacc atcgacaggg ctggagaaga
     7261 agggaaacag caaaggctcc atgctgctga tttggcgacc gttcatcagt cctcgacgga
     7321 tgtttactac cgtatccaaa gcggcattga tggcgatcgg gcagggtgtc aggagggctg
     7381 catgataaat gtcgttagtt tctcgggtgg caggacgtca gcatatttgc tctggctaat
     7441 ggagcaaaag cgacaggcag gtgaagacgt gcattacgtt ttcatggata caggggcaga
     7501 gcaccctaaa acatatgagt tcatccgaaa tatcgtcagt aactggaaaa tagacttaca
     7561 ttgccttcgt gtaataccta atccagaaat ggggaaggcc agtagttatg aagagatagg
     7621 tgtcaatgat attggtccag atcttatacc gtggaaaagg atgttaaata aatacggaca
     7681 tccatatatc ggcggtgcgt tctgtaccga cagaatgaag tctgttccat tcaccaaata
     7741 ttgtcaggaa aagtttggga aaggaaatta catcacatgg cttggcattc gcacagatga
     7801 accaaacagg cttaaaaggg ctaatggttt tcggtacctg gctgatataa gcgattttga
     7861 aaaacaggat gtgcttgatt ggtggagtgg gcagaagttt gatcttggca tacaggagca
     7921 tcttggtaat tgtgttttct gtataaaaaa agtatgcaaa aggttgcgct ggcagccatg
     7981 gatgagccag aacttgcaga tgcatttatc aacatccttg atacagaaat aaaaacagga
     8041 aaggaaccgg ttatgtatcg agggaataat acacttaaat cactgattgc cttgtttagt
     8101 gatatatcaa gagatgagtt agcctcaaga atgacatcaa tgcgacagta tgattcaggt
     8161 tcgtgttctg aatcatgtga agcattttca tgtcagcttg gatttaattt tgaggatgcg
     8221 gcatgaggcg acagcgacga agcatcaccg acataatctg cgaaaactgc aaataccttc
     8281 caacgaaacg ctccagaaat aaacgcaagc caatcccaaa agaatctgac gtaaaaacct
     8341 tcaactacac ggctcacctg tgggatatcc ggtggctaag acatcgtgcg aggaaatgac
     8401 aatggattat tcacagttaa gtgattttga aattaacgtg gcggtattcg aagccattca
     8461 taacggatca ccggattaca aagaaggtga gaatggcgat atggtgtttg tctcatttga
     8521 gggagacatt gtaaacggag acgcagttga agtagaagtt gagcgcggat cctttaaccc
     8581 atgcgcaaac ccagcagacg catggccgat tattgaaaaa tacaggatta gcattatcaa
     8641 tctcgatgaa gacgagtggg gtgcacgcgg tgtggcctac tgtaaatcta agcgagctat
     8701 acatgaaaat cccctccgcg ccgccatgat tgtctttctc atgatgcaga gaatccaata
     8761 atgcttagcc catcccaatc ccttcaatac cagaaagaaa gcgtcgagcg ggctttaacg
     8821 tgcgctaact gcggtcagaa gctgcatgtg ctggaagttc acgtgtgtga gcactgctgc
     8881 gcagaactga tgagcgatcc gaatagctcg atgcacgagg aagaagatga tgaatgagtt
     8941 aataaatggc aatgccatca aaatgacaag cattgaaatc gctgagttgg tagaaagccg
     9001 ccatagcaat gtaaaagtat ccatagatag attggtgaaa cgtggcgtta tcaagcctcc
     9061 tgcattgcag tacactaaca taatcaatga tttatgtgtt attaccggga agcgtgattt
     9121 ctacgtcttc gaaggcgaac aaggtaagcg cgacagcatt attgtcgttg cccagttgtc
     9181 gccagagttc accgctcgcc ttgttgaccg ttggcgagag cttgaagaaa ctgcggttaa
     9241 tatccccaaa acgctaccgg aagcgttgcg ccttgctgct gatcttgctg agcagaaaat
     9301 gcaactggaa aaccagcttg caattgccgc acctaaagtt gagtttgccg atcgcgttgg
     9361 cgaggccagc ggaattttga ttggaaactt tgcaaaggtt gtcggtattg gccaaaacaa
     9421 actgtttgca tggatgcgcg atcacaaaat ccttattgct tcaggttccc ggcacaatgt
     9481 gccaatgcag gaatatatgg atcgcggcta tttcacagtg aaagaaacag cggtcaacac
     9541 aaatcacgga atacagatat cgttcaccac aaaaatcacc gggcgtggtc aacagtggct
     9601 gaccagaaag ctgctcgata acggaatgct gaaagtaaca ggggaggctg cttaatggct
     9661 aacctacgca aagaagcgcg cggcagagaa tgccaggtac gtatttacgg catatgcaat
     9721 gacaatcctg aaactacagt tctggcacat taccggatgg ctggaatttg cggaactgga
     9781 atgaagcctg acgacctgat cggcgcatgg gcttgtagcg cgtgtcacga tgaaatcgac
     9841 cggcgtacaa tgattctcga caacaaagac gccagacttt accacctcga aggcgtgatc
     9901 aggacgcagg cgatactgct gaaggagggg aagattaagt catgaaaacc taccgaataa
     9961 aattgccgtg gcctccttca aacaaccgat attggcgaca ctcaagaggg acccactaca
    10021 tcagcgactg ggggaagaga taccgaaaag aagtaatcga attaattcag caacaacagc
    10081 tagacatcaa aatcacacct cgcatcagaa taaccatcca cgcagcacct cccgataacc
    10141 gcaaacgaga tttggacaat ctgcccaaag ccgtttttga cgcactcacc agtgcgggct
    10201 tctggctgga tgacggtcag atagacgata tgcgcgtcaa gcgctatcag gcgattaaag
    10261 gtggaatgct tgtgttggtt gtgactgaaa catgcgggag tttgccaatg attacagagc
    10321 tactggaggc cgcatgacgt tctcagtaaa aaccattcca gacatgctcg ttgaagcata
    10381 cggaaaccag acagaagtag cacgcagact gaaatgtagt cgcggcacgg taagaaaata
    10441 cgttgatgat aaagacggga aaaagcacgc catcgtcaac gacgttctca tggttcatcg
    10501 cggatggagt gaaagagatg cgctattacg aaaaaattga tggcagcaaa taccgaaata
    10561 tttgggtagt tggcgatctg cacggatgct acacgaacct gatgaacaaa ctggatacga
    10621 ttggattcga caacaaaaaa gacctgctta tctcggtggg cgatttggtc gatcgcggta
    10681 cagagaacgt cgaatgcctg gaattaatca cattcccctg gttcagagct gtacgtggaa
    10741 accatgaaca catgatgatt gatggcttat cagagcgtgg aaacgtcaat cactggctgc
    10801 ttaatggcgg tggctggttc tttaatctcg attacgacaa agaaattctg gctaaagctc
    10861 tttcccataa agcagaagaa cttccgttaa tcatcgaact ggtgagcaaa ggtaaaaaat
    10921 atgtcatttg ccacgccgat tatccttgtg atgaatacga gtttggaaag ccagttgatc
    10981 atcagcaggt aatctggaac cgcgaacgaa tcggcaactc acaagacggg atcgtgaaag
    11041 aaatcaaagg cgcggacacg ttcatctttg gtcatacgcc agcagtgaaa ccactcaaat
    11101 ttgccaacca gatgtatatc gataccggcg cagtgttctg cggaaacctc acattgattc
    11161 aggtacaggg agaaggcgcg tgggcataag agaactaaac ctcaccaaag aacagcatga
    11221 gtggctgaat ggctggcttg aactgtgggg cgcatgggtt tattcaggtc gtctggaaaa
    11281 gcgcatgagc agcgtaatag cgaagttcat ggagagcgta gagccgggaa gagttatgac
    11341 aaggccaatg tgtaatgatg atgatggaat gttgatttct caggtcgtcg attccgtcat
    11401 gtgcattgac aagaaagcct ttggtatcct cctcagctac tacgctcatg gctcttccaa
    11461 gcacgccatt gcatcttact atcattgcgt cgcaagacct cgcaagatgt tatgccgtgg
    11521 cggtgggcgc attcaaaaac catcgctcgc aacctgtcga cgggaagttg acgaaatcct
    11581 taacgcctcg ttgtttatga tttacccggt tctggatagt gcgtttaaaa atcggaaacg
    11641 tgtagagaaa attaaacatg tagcatagaa cgtgttgaca tcattgagca aatgagcaac
    11701 actattcgca taagctgccg ttagtgactc ttaagttgca acggtggctt tttttgtttg
    11761 cacaacaggt aagagcattg aaccagcaga cctcgcggaa ttggtgaaag gtgccgcgca
    11821 gtgctcttat cgttgtggtg aagctcaatg gcgagctagc agataggcga cagtgaaaat
    11881 actagtcatg tagctgaccg ccgcgcgtac tgcaatcggc agcgcaccga tggaagccgg
    11941 ttcgattccg gccgccacaa cccaaactga gccgtagcca ctggctatcc tgaattcatc
    12001 agtgatagtt acgctgcggc cttctacaca tgatcttcgt gaaagcgggt ggcaggaggt
    12061 cgcgctaaca acatcctgcc gttttgcccg tgcatatcga tcacgaacaa atctgattac
    12121 taaacacagt agcctggatt tgttctatca gtaatcgacc ttattcctaa ttaaatagag
    12181 caaatcccct tattggggct aagacatgaa gatgccagaa aaacatgacc tgttagccgc
    12241 cattctcgcg gcaaaggaac aaggcatcgg ggcaatcctt gcgtttgcaa tggcgtacct
    12301 tcgcggcaga tataatggcg gtgcgtttac aaaaacagta atcgacgcaa cgatgtgcgc
    12361 cattatcgcc tggttcattc gtgaccttct cgacttcgcc ggactaagta gcaatctcgc
    12421 ttatataacg agcgtgttca tcggctacat cggtactgac tcgattggtt cgcttatcaa
    12481 acgcttcgct gctaaaaaag ccggaataga agatggtgga aatcaataat caacgtaagg
    12541 cgttcctcga tatgctggcg tggtcggagg gaactgataa cggacggcag aaaaccagaa
    12601 atcatggtta tgacgtcatt gttggcggag agctattcac tgattactcc gatcaccctc
    12661 gcaaacttgt cacgctaaac cccaaactca aatcaacagc cgccggacgc taccagcttc
    12721 tttcccgttg gtgggatgcc tatcgtaagc agcttggcct gaaagacttc tctccgaaaa
    12781 gccaggacgc tgtggcactg caacagatta aagagcgtgg cgctttaccg atgattgacc
    12841 acggtgatat tcgtcaggca atcgaccgtt gcagcaatat ctgggcttca ctgccggggg
    12901 ctggttatgg tcagttcgag cataaggctg acagcctgat tgcaaaattc aaagaagctg
    12961 gcggaacggt cagagagatt gaggtatgag cagagtaacc gcgattatct cagctctggt
    13021 tatctgcatc atcgtctgcc tgtcatgggc tgttaatcat taccgtgata acgccatcgc
    13081 ctacaaagag cagcgcgata acaaggccag tgaactggag aaggcgaacg ccaccatcgc
    13141 tgacatgcgg aagcgtcaac gtgatgtagc agaactcgac gcaagataca caaaggagct
    13201 tgctgatgct aacgcgacta tcgaaagtct ccgtgctgat gtttctgctg ggcgtaagcg
    13261 cctgcaagtc gccgccacct gtgcaaagtc aacgaccgga gccggcggca tgggcgatgg
    13321 agaaagccca ggacttacag cagatgctga actcaattat taccgtctcc gaagtggaat
    13381 cgacaagata accgcgcagg tcaactacct gcaggaatac atcaggacgc aatgcctgaa
    13441 ataatttttt tgcaaatcac aaagtccatt taatgagcct cgcgatgcgg ggcttttttt
    13501 acatctgaat ttcacagcgc atctcacgcg catattacat cacccgagcc tttcagaaag
    13561 ttgagcctga gaactgccgt atatggtggc gaccatctcg gggcggcttt tctgtgagac
    13621 aggctcactt tctaaaaggt aaagacgcta tgaataatcc gtcagttatt ccggccttcg
    13681 acttccgcga aatggtcacg accctcgaca acaatataat caccacatca ctcaaggtgg
    13741 cggattactt tggcaagcga cacaaagacg ttttgcgtgc catacgcaac ctgaaatgct
    13801 ccgatgactt cacccagcgc aattttgcgc ccattgattt cattgataaa aatggcgatg
    13861 ttcagcctat gtataacatc acccgcgacg gatgcatgat gctagtgatg ggattcactg
    13921 gcaaaacagc tgccgcagtg aaggagtgtt acatcaatgc cttcaactgg atggccgagc
    13981 agctaaaccg gcgcatggcg atgggtgaag aattgcagca tcgctacgcc atcaaagaaa
    14041 cgcgctcaaa gctgaaaggc acaatcggca gccggttgat gaacgagcgg aagaaagaga
    14101 agcgcgttct ggagctcgag catgagcaca tcatgcaggt gacgcagcca gaactgctga
    14161 ttggctgatc gacattacag agccacttcc agaggtggct cgataatgtc acaacgaggt
    14221 aaggattatg gcaaaaccgg actggggagc actgcaacac cagttcctcg ccgagcatgc
    14281 caaaacagga atatccccga aagactggtg cgcagcgcag ggactgaatt actcatctgc
    14341 gaaacgctat atcaaagtaa cgacttacgg tgcgaattcg caaaaaaaaa ctgcgaacaa
    14401 atctgcgaat tcgcagaagg agaaaggcgg ggtcagtaaa aacggggagg tgaaaaaaaa
    14461 ccagcccgac acaggcgccc actcaaaatc tccagaaacg aaaccgatac gcggatcgcg
    14521 cactgctccg ccgacgaacg ccttccagcc tggcaaccag aacgcattaa agcatggtgg
    14581 ctatggccgc cggatgctgc tatctgacgc catcaccgaa gatgccaaga tgctcacgct
    14641 cgacgatgag cttttctggc tgcgagcggc gagcctgaca gcggcagaga atatcgggcg
    14701 ctggcagaca gagctggaga cagccgccag cgagcaggcc aaagatctgc acgacctcat
    14761 ctctcaggcg cagaaagcca tgcatcgcaa cactgcgcgc attgagtcgc tggagtacac
    14821 caaggcggcg attatcaagc agcgcgttga tgccgcttac cgcgaagccg cgaccgaaaa
    14881 ggttgagctc gaaattgatg tactgaaaga cggcgacaag gataacgcga tcgtcgtgca
    14941 taactcgctg ccaataccgg gaagataaat catggccgac atttacctac ccacgctaca
    15001 caacgggcag ttaacggtct ggtctgattc ctgggatcac cagttgaatg cggttcgctg
    15061 tggtcgacgc tgggggaaaa ccttcatgct gtcgagcgcc gcggtgacct acgcaacgtc
    15121 gcagtttcgg cgcccgggca tggacatcga gctgggcggc cgggtcggta tcttcactgc
    15181 cgagtatcgc cagtaccagg agatctacga caagctggaa gaaatcctgt tgccgctgaa
    15241 aaagagtttc agccggcagg aaaagcgcct gctgctgaag aacggcggga agattgactt
    15301 ctgggtcacc aacgacaaca aactggccgg tcgtggccgt gagtacgaaa ttatcctgat
    15361 cgatgaggcg gcgtttacca agtcgcctga aatgctgaag gaaatctggc cgaagtcgat
    15421 taagccgacg ctgctgacga caaagggccg ggcttacgta ttctcaacgc ctgacggtgt
    15481 ggacgaagaa aacttcttct atgccatctg ccataacaaa gacctcggct tccatgagca
    15541 tcacgcgccg acgtcatcaa accccttcgt tcctcccgag gagctggaga aagagcgaca
    15601 gaacaacgat cctcgcgttt tccggcagga gttcctggcc gagttcgtcg actggtccgc
    15661 tgcgtcgctg ttcgacgtcc gcaaatggtt cgagggtgaa aaccaggatc agcctgtcga
    15721 ttaccctgag atgtgccagg ccgttttcgc tgtcatggat accgccgtta agggcggtac
    15781 tgagcacgac ggcacggcgg tggtttacta cgccgtagac acccggcccg gaattcagcg
    15841 cctgaccatt cttgactggg atgtggtgca gatcgacggc gcgctgctgg aagagtggat
    15901 tccgtccgtt ttcacccggc tgaatgagct atccggccag tgcgtcgctg taaatggcag
    15961 cctcggcgtt ttcattgaag acgccagtat gggcagcatc ctcctgcaga aaggcgaaag
    16021 cctgggatgg ccggtcaaca aaattgaatc cgctctgacc agcaaaggga aggatgagcg
    16081 cgccattatg gcctccgggt atcactaccg cgggctggcg aaaatatccc gatacgccta
    16141 cgagaagacg gccgtcttca agggcgaaac agcaaaccat ctgcataagc aggtatcacg
    16201 attccacctt gccgataaga acgcgcacaa gcgcgccgac gatttgctgg atgattacac
    16261 ctatgggctg atcatcgcgt tcggtagcgg cgacgcactc tagcgagaaa accaatgaac
    16321 gaagatgata tcgcaatcgg cagttgctcg ccggagctga tcacgctcct ggacagcgat
    16381 gacattcagc caggtatgtc ggctggctat cagacctgca aaacgattta cctcttccac
    16441 ccgttgggcg ggaaaatggt agatcgcccg atcaagatgg cgatgaacga gtcgcgcacg
    16501 gttcacattt cgcaggcgta tggcattgag cagcgtctcc gcgatgcatt tgagcgggag
    16561 tggaaagcac tgggcgccga taagcacatc gctaatgcgg cgcgcatctc tcgcatttac
    16621 ggtgtttcgg cgatcgcaat gctggttgat aaccaggagc cgtcctctgc ggtggactac
    16681 cgcacgctgt ataagcacaa cgtgacattc aacattctcg acccgctgaa cactgccgga
    16741 agcatcgtcc tgaaccagga tccgaacgcg caggactttc agaaggtcga cgggatcaga
    16801 gtggcgggca agccgtatca caaatcccgc tgtgttgtgc aacagaacga ggacccgatt
    16861 tatctggcct ataactctgc tgcctttggc tttaccggtc gcagcgttta ccagcgcgct
    16921 ctgttcccgc tgaaatcctt catccagacc atgcgcaccg atgacatggt ttccgtgaag
    16981 ggtggcttgc tggtaacgaa gattcaggga ccgagctcag tcgtcaacaa catgatgcaa
    17041 aagctcagcg gcatcaaacg aatgatgctg aagcgaggga agacaggcga agtcctgcag
    17101 atcggcgcaa atgacagcat cgaatccatc gacctgagca acctggaaaa gccgctcgac
    17161 tcctcccgga atcacattct ggagaatatc gctgcggcag ctgacatgcc ggctatcatt
    17221 ctgaactcgg aaacattcgc ccagggcttc ggcgagggga cggaagacgc tcgatctgtt
    17281 gcagtctaca tcgacaacat ccgcgagtgg cttgagccgc tgtatgacta tttcatccgt
    17341 atttgccagt atcgcgcctg gagcattgag tttttcaatt ctctgcgtgc tgacttcccg
    17401 gagcttaaaa acacgtacag cctgtatttc tcctcatgga ttaacaactt cgaatatcgc
    17461 tggccgtcat ccctgaaaga gccggaaagc gaaaaagtga aggtcgacga aatccgcttt
    17521 aaggccatcg tcagcatgct ggaagtcctt ctcccgcagg tcaacacgga tgatgagaac
    17581 cgcgctcttc ttatcgagtg ggcgcagacc aacgcgaacg ctaacgaaag cctgttcccg
    17641 cagcgacttg atctcgatat cgactcgtta aaggctaacc ggcctgaaca gccacgggat
    17701 gaagagcccg gcggcgggat gatgctatga agactttcac gcgcaccgta cgcgaggcgg
    17761 tgaagttctt tctgcgcaat ggctacacct cgcggcagga gctggagcaa tggcaggcca
    17821 ttatccggca ggcagccgaa agcgaaaccg atgacgacta catgagcatg gtgtcagatc
    17881 ggttgcgtaa gacctatgac ctgcaggtga gcaaggctgg agcgctggag cgccacaagg
    17941 ggctttcacg cttcacgctg aactacatgg agccgaagtt acgcagcgag ctggatcgcc
    18001 gcatcctggc cagcgctgac ctgataaagc tgaatcgcaa gaaagccatc gacactactc
    18061 tgtcgcggtt tagcggatgg gccagcagca ttccctcagc agacagcatt gcgctgaccg
    18121 gcattcaggg aacgatgcgg gagacggcgg cgcacattca gaaggccgcc gagagggtgg
    18181 actatgaagc gcgccgcgtg atgattgacc agagccataa gctgatcgcc aatatcgaca
    18241 acatcatcgc gactggcaac aacgcgattg ctgccgagtg gcatagccac tggcgccagc
    18301 cagggtacga ctaccgggaa gatcacaagg agagggacaa gctgatctat ctcatccgtg
    18361 ggaactgggc gcagaaaaat ggctatgtca aagctggccc tgccggctat ctcgacgaaa
    18421 ttacgcagcc tggcgaagag gttttctgtc ggtgctacgt cacctatctg tacaacctcc
    18481 gcagcattcc cgaggacatg ctgaccaaga agggccgcaa gttccaggag tccatgaaag
    18541 cagcatagga gcattaaaac gtggctattt ttggcagcgg gataatgttc cgtcagggga
    18601 agttcgtctt cctgatccag cgctcggatg atggcacatg gtgccagccg ggcgggacga
    18661 tagagccggg agagttagcc atagacgccg cacggcgcga ggtgctggag gaaacaggct
    18721 atcagtacga tggcccgctg acgccgcaca gcgtacatgg tgactacctg acctaccgcg
    18781 ccgacgtgcc ggagcaattc gaagcgaaga taaacgacga atcgctggcc gccggatggt
    18841 tccatattga agatctgcca aagccgcttc atcagccatt cgctgaaatg ctggcgcagc
    18901 aggcgctcaa cgaaaccgac gtggccgcgc tcatcgctga cggaacgctc agcagcccgc
    18961 aatattttta caacatgtgg atgttcgcca tccgggtgac cggaacaggg gttacctggc
    19021 gatctgcaga tcaggagatg acgttccgta acccggacga ctatctcacc cctgaatttc
    19081 tccagcgggt agctggcgta ccacttatct ggcttcaccc cgaaaaaaga acacttgata
    19141 gcgacgagtt ctcaaagcgc gttattggca ccctgacaaa tgcctgggtt gccgataagg
    19201 gcgaagtgtg ggccgttgcg cgtgtgtacg acgccgaagc tgctgaaatt atggcaacaa
    19261 ggcaattaag cacctcgcca actgtgaagt tctcagaggt tgctcaatca atcattgtcg
    19321 acggtcagcc tctactggtg gagccatccc ccgagctgct cgaccacgtt gcaatttgtg
    19381 aacagggcgt gtgggacaag ctccttgccc ctaccggtgt taaatctgat tccattcctg
    19441 aagaggctga aaagatggac gaggaaaaaa tcgtagcgct gattaataag gcgatcgatg
    19501 cgcgtttggc taaggccgac gaagagaagg aagcgaaagc caaggctgac gccgaagagg
    19561 ccgccaagaa agaaaaggct gacgcagaag acaaagaagc ggaagaggcg aaagctaaag
    19621 ccgacgcgga agagaaagcc gcgaaggaaa aagctgatgc tgaagccaaa gaaaaggcgg
    19681 atgccgaaga ggctgagaaa atggcaaaag aaaaagccga ctctcaaatc ctccaggaaa
    19741 ttgctgagct tcgctcccgc attcctaccg aactgagcga cgaagagcgc aacgaagttg
    19801 cagaagcgca ggtgaaagcc gatagcgtct tctccagctt tggcaaacgc gcccctatcc
    19861 cgctgtccgg tgaaaaaccg atggcgtatc gccgccggct gatgattcaa ctgcaggagc
    19921 attcgccgga ctacaaagcc gtcgatctct ctgccatcgc tgattctcaa ctgctgagca
    19981 ctgccgaaaa gcatatctac gctgatgcgc agaaggcggc aagcctgtca gttggtcccg
    20041 gtatgctgcg cgagattaag cgcgccgatg ctaccggacg tcagatcagc acctttgaag
    20101 gcgatcccgc cgtcacctgg gcgccgttcc agtctggcaa gcgtcaggtc accagtttta
    20161 acaaccaggc ttaacgggag ctctgaagca tggctaattt atctcttaac ccgatggcga
    20221 ccactaatgc tgctggttcc ttcggtgtgc agtctgatgg cttcattcag ggcgttgctc
    20281 tggatgatcc ggcaaaccgc tttaacctgg cgtccggtac tgtcgccgcc accgaaacca
    20341 aaccgctatg gggcggcctg ccggttgccg agttgcttcc cggcgttaac tccagtcctc
    20401 gcgggtcgac tattcgtcgc gctgcgtcac tggctgagct cgaaggcttc accgtcttca
    20461 accaggctca caacgggctt actactccgc aatcaccggt tccgctgtat gcgtccggca
    20521 tgagcgtttc attctatcgc cttggctcca acatgcgcgt gccgctgaaa gcgtcagcgc
    20581 aggtggtcgc gctgggaacc gctggcgcat cggtgaaaac gccgctggcg tgggacttcg
    20641 tcaataacca ggtgaccacc gcagccgcgg cggcttttgc cggtgctgac attgacacga
    20701 ccgctgttac ctactcgaac ggcgtggcca ccgccaccac tgcctctgca catggtctga
    20761 ctgcaggcca gtacgtgaag atcagcggcg tagctccgac tgcctataac ggcaccgtcg
    20821 ttgtgctgag cgtaccgagt acgacaacct tcacctatgc gcctgccagc gcgccgggcg
    20881 gctccgcgac cacgcagggc actatcggcg ctgttgctca ggcagacatc accctgccag
    20941 tgaaagtcat ctccatcgag agtgggaact ctaaaactgt cagctatgac agcgctacgg
    21001 gcttccttac ctggaacaac accgacagct gcgcgctggt cttactttaa tcgggagctt
    21061 taaatggctg caattacccc cagctacacc atcgtcaacc cgtcgtatat tgcgccggag
    21121 ttgatcattg gttaccagca ggcgtccggt gcgttcgaaa ccatcgccag cggtaacccg
    21181 caggtccgcc ttggcgtagg cgaccagtac gtttatatgc gccgcctgga tattcgtacc
    21241 caggtaacct ccagccagtc cggcaacgcc aaccagctgc cgagcgtggc gctcgaggcg
    21301 cgcatgatct ccactccaac ctacctgttc cgctgccgtg gtatctacga tcaccacgac
    21361 accgcggcgg ccggtaactg gaacgtggca ctgccagaag ctcagcgtct cggcatgcgt
    21421 cagggcatct tccagcagtt gcgttctgcg ctgctgtacg gcatgaaccc ggcaggcggc
    21481 gaaggtctgc tgaacaccgc aggcgcgacc accgaaaccc tgccgcagga cagcaacagc
    21541 aacaccactg tgctgaccta cgaccatgga cagatggctg tctatctgct gggccatgta
    21601 caggccgcgc tgacccgcac catgcaactg ggtcgccagc agcgtgttgt tatcctcggg
    21661 ccgcagcgag tgctgggcgc gatggagatt cagcagatcg ttcagctgac atcttatcag
    21721 cgtcctggcg gcggtactga taccgtcggc ggcaccgtga aagaggttct ccgtggcgcg
    21781 aatgttcagg ttgactgggt gtacgacgac acgctgatcg gcgccggtgc cggcggtact
    21841 gacgcggtgg ttatcaccat cccggaagtg gaagtgccga tggttaactc caccgtgaac
    21901 accaacgaat tcgccaaact gagcccgtct ctggcggcta atgccctgat gttcaccgac
    21961 atggcggcac cgatggaaat cccgacgcca atccccgggg gcgctatcga cgtgctgtca
    22021 gaaatgcgct ctacggctgg ctgggcagtc cgtccggaag ctatcaccat cctgtcgatg
    22081 aaatacagcg actaaaactc gaaattgaga agtgcttaag cctctgcatg gttcgctgtg
    22141 caggggcttt tttacgaagg gtaaacaatg aaactgtaca tcgccaacac taccaagcag
    22201 cgacacatct tcactttccg ccagctggaa accgggcgcc ttcgccagat ccccattgag
    22261 cacggctcac agatgctggt tctggatggc tcgaccgaag aagtcgaagc ggttattcag
    22321 catcatcagg tttacggtct ggttgactca accaaaatcg accagagcca ggcatttgtc
    22381 ggcctgtgct acagcatcaa caaacccgtt tccgccagcg ttattgagaa aaccattcgc
    22441 gataacgatg gtcatctgac ccgcggggct cataaccgcc ggcaggcatc cgtcgccgcg
    22501 ctggataaca cactgcgcga aagcggtatc ggctacgaag gtgacatgga attcagcgca
    22561 gagcaggcca aggggcgcga tgaccattca gacgacccga ccatcaacga aaaaattgtc
    22621 acgccgaaag ccgggagcaa gaagaaatga ccaccagtct gtcgggattc atcgaattcg
    22681 ttcgatctga tatgggcatc acccccgacc aggttcccga cgactcgccg tctttttctc
    22741 tcgcctatgg cggcgccatt gaatgggtta acccggacat cgcgtgcgtt atgcctaaca
    22801 tgtacagcat cgcggtttat aaccttgggg catcgtttct catcaattac gggacagagg
    22861 ctgtgtttgc tgagttccgt aaacaatatg ggctgaatga cttcaaagcc ggggttatca
    22921 cgggagccgg ggataactct accagcgcac agcgcctggt ccctgatttc ttcaaagacc
    22981 tgtcgctggc agatctgcag atgctccagg atccgtgggg ccgtcgctac ctgatgttcg
    23041 ctcagcagtt cgggagcctg tggggtctga catgatcacc tttcatctgg gcgttatcga
    23101 tatcccctac gaggacgagg acaccacgac ggggagcgta gcggaagagc tggaagctag
    23161 gtatcagatt atgcagacgt tctttgaccg ctacgggaac gacatcgctg agctgatgag
    23221 caaagacctg gccgcagcgc ttgaaaacat gttcgctggc gcgccgccgg caaaagaccc
    23281 gctcgctgag tcaatgtcca aagttcacga tctctttgtc ggcttcctcg ataacaccga
    23341 gatgaacggc ctccctggcg taccaacgcg ccgcgcgctt gagggaatat cgaagcgctt
    23401 taaaggcaaa aaggggccgc cacgcccttc gttcattgac acaggaacct atcaggcagc
    23461 tatgcgagcc tgggtaagcg gggtgctgaa tgccttccct gagtgagtta cagaacgcca
    23521 aaaccgagct taacgctacc ctgacacagg ggctggatga tctgagccgg ttccaggtgg
    23581 tgacgttcac gaagtacatc agaaaggtac ttccgctcga tggcttcgtg ttctgggtga
    23641 aagcctcggt cctgtcagac gatccgaaca atgagccgga tacggtagat gtgaaaggtt
    23701 atttgcacct gacgaccgaa accattcagg acgacgagca actgtacgac cgcaacgtgg
    23761 tgacgttcac cgcgcaggcg gacatcgacc cgtttaacga catcgggtca gaggtgctgt
    23821 acatcggcga gttttttggc gtgcagttct cgttctcccg gcgtaccggg ctgaatgaac
    23881 cggcgaacct gtaccactac accggagagg ctatttttcc gcacatgcgg tcgcagatca
    23941 tcaactctgc ggatgacata gacctctctg acgtggtggt gtcgagctcg ttgccgatct
    24001 ggttggccct gaatcagtac atgccgatgt tcccggcgat gctctcaacg cagaaccttt
    24061 ctccgcccta tgcgacggtg aaatgcagta acacgtcacc gatcgccggc gctttctatc
    24121 tggacgagaa gcaaaaccag tatcagctgg tatcggaaga tgtgacgctt tcggtcaccg
    24181 gcctgcgtaa cgccagcatt gaagactttg tgcggtatgt gcaggactac acgaccggcg
    24241 atgccccgga gatggggatc atgaatattc ccgtcgtgca ggatgagcga gtcactcaga
    24301 acgagctcaa catcattgcc atgcgtaaga ccatcaaatt caaaatcaat tactaccagc
    24361 aacggatgcg taatttagcg cgccagttga tcacgtctgc aattccgtcc attgacccgg
    24421 agaaataagt aaatggcaat tgttaatatt aacgtgtcgg tgacgaatcc gccgaagccc
    24481 tcgcagttgt taaagtccgg ggcgatgatt tctatgggcg gcacgacgct gaatgccggt
    24541 gaatatcagc tgctgaccag tgaaaccgac ctggccgaca tccttgcacc ggcgaaaacc
    24601 atctcgacgc tcgcctgggc tactggcgtg gtaaccgtca cgctggctgc cgctcacgga
    24661 tggactaacg ggtcgcaggt cccggtgatc atttccggcg cgactccggc ggggtacaat
    24721 ggcgcctata ccgctacggt gacaggagcc aacaccttca cctatccgct gacgaccaac
    24781 ccaggaaccg caacggcaat gggaacggta aaaacggtag tgcagaccga aatttcccag
    24841 atgaatacct cgttctgggc ccaggggaaa acgcgggcag tttatgtgct ggaacttggc
    24901 gatgtgtcca tggaggaagc tgtcgcagcg ctgacaacct tcatcgctga agacgtcgcc
    24961 ctgggcaaca cctaccagaa gtttttctcc tatctggtgc cgcgcgaatg ggattcggtc
    25021 gatgaattta aaaccctgac cgggctttat acctcgccgg gcagcctggt ttacttcttt
    25081 gtcaccacaa cgatcgcgac ctatcaggat tgggtcgcga cgaaaaacaa aactgtcttt
    25141 gccggcgtcg aggctccgga tattccggcg agcgagtttt ccatggccgg cccgttccag
    25201 tcgtccctgg caaacgaccc ggggtcgagc aacatggtgc cgccgatgtc gtaccgcttt
    25261 atgtacggcc tgactgagta cccgctggaa ggcaacagcg cactgctgaa atcgcttcag
    25321 gacagcaaca tcaactacat cggcaccggc gccgaaggtg gactcagcaa taaagtgctg
    25381 ttcaccggcc gcatgctcga cggtaacccg ttcaactact ggtattcggt ggcgtggacg
    25441 gcgatcaacc ttgagctcga cctggcgaat gaaatcatca gcggctccaa cacgaccgtt
    25501 aacccgctgt actacgagca gaagggcatt gaccgcctgc agcgtcgcgc tctgaaaacc
    25561 atgcgtaatg gcatcagcta cgggctgatc ctcggtcgcg tcatcgacac gcaactgacg
    25621 caggaagatt tcaacaccga gtatgacaaa ggcacttacg ccggcaacgc cgtgatcaac
    25681 gccgtgccgt tcagtaacta caacagcctg aacccctccg attatcagga aggcaaatat
    25741 aacgggctga gcgccgtcat gacgccgcgc cgcggcttcg aatccatcac gtttaacgtg
    25801 aacgtaacga actttgtagg ggcgtaaaaa atggcgaacc cattagtacc gcagggcttc
    25861 cttaaccgcg tacgcggggc tctttccgtc acggacacac cggcgctgaa cgtttcggcg
    25921 tcgtacctgg caaaggacgg cattagcctg cgtccggatg gcccggcgac cgacatcatc
    25981 cctacgatga ccggaaccgt cggcagccag gcgccgtatc agcaggtaac gctgaccgtg
    26041 catctcctga aaactcaggg gctgggcgaa agctaccggc aacgcttttt aaccgacacg
    26101 tcgctgggtg aaatcgtggt aacgccggat gcaacgacgt tcggcaatat cacgctgctc
    26161 aactgctatc tggtcaactt caacgagctg gctttcagcg ggatggaccc ggcttttgtg
    26221 gtaaccatca gcggctatat ggtcaccaac gacaacatgt gggtgtaatg catgaaaatt
    26281 gacaagaaac tgaatctggt caccaacgtt acccgcgaag acggctcgat cgtatacctg
    26341 catgtgacgc cattccccta tgaggtggtg gaagaacact gcatcctgct ggggaacctg
    26401 ttcacaaaat tcatctcgca ggtgggtggt cttggcgccg ccagaatcgc cgcgatgatg
    26461 ctgaggcaga gcctgaaagc ggaaatcgat aacggtcgga caggtccgaa catcgttgat
    26521 gaaattcagc gactgacggt cgttatccat aacgtcggcg gccagtggaa aaccacgcct
    26581 cttgaggtgg cattcaagca ggggattatc gaccctgatg agtatcgcga ggtagaaggc
    26641 gaagtggttt tttttatggt ttcctctgct attcagaagg caaacctgat cgcgccgacc
    26701 gtgggaacgg tgatcaaaat gtacgatggg caactaacct catcgagcgg tacggcgttc
    26761 cgcgattcgt tgcagacgtc gaagccggat accgatatcc cgacccagaa tgcccagccg
    26821 gaaacgtcat ttataccctc ttagactggg cgtctaatga gggtttctgg caggtgataa
    26881 gggagatcac cggcgaggag tatgcaagcc cggcgcagta ccggcagcgc tacctactcg
    26941 ccgcgctcaa agaaagaggt ttcttcaatg gtagctaagt cgatcgtcga cattgacgta
    27001 aatgacgaca agtttgtcgc gtttatggaa aggtttcgcg agtaccagag cgcgctggat
    27061 gatttaccgg aagcctggcg agtggctgcc gttggtattg gtgaaagcag caagcagacc
    27121 gaaaaagcca aaggtgaggc gaaggagtta ggcgcggagt ttaatgccgt ggccgaggcc
    27181 atcctgacca tcaacagcgg tatcgatcgg ctcaatgcca acctggaaga ctcgaagaaa
    27241 aagcaggacg aattcaataa aagcactcgc tctgcgaagg gcttccttag cgatgcgacg
    27301 aaagacgcta aatcgctggc agggcacatc aaggaagcga cggccagcct tctgtcctgg
    27361 ggtggtattg tcgggatatt taccggcgtc ctgggcgttg gcggcctgtt tggcatcaac
    27421 cggctggcgg ccaccaccgg cgcccagcgg tttacttctc tcgggctcgg gacgagcatc
    27481 ggcgcgctgg attccaccgc cataaactac cagaaagcgc tgggtaatcc ggcggggacg
    27541 ctgggcgcta tccgcgattc ccagatggac ctgtcgaagc gctggacgtt tcaggcgatg
    27601 gggattaaca atcccgacca ggacccggcc aaactgctcc cgcagatgat ccgtaatgcg
    27661 cgcgatatct tcgtgcagaa cggcagcacg ctgcagggcg cacaggcgca cggactgaca
    27721 aacttcttta cgctggacga ccttaaccgc ttcaaaaaca tgagcgatga ggagatcacc
    27781 gccatggaga agcgcgcgca gcaggatgcg cgcatgttgc aaattaccga ccagcaggcg
    27841 cgtcagtggc aggattttaa cgtccagctc gattacagca gccagagcat cagaaacacg
    27901 tttgtgcgcg gcctgggtcc tctcacacct caactgagca agctgtcaga tgcgctgtca
    27961 ggcgcgatcg ataccgttct gaaatccccc gaactcggca agtggattga tgcgcttgcc
    28021 ggtggcattg agcgattcgg taattacctg gcttcgccga cgttcaaaag cgacgttgag
    28081 tcgtttatgt cgggcgttga gcggctgggg cgcgtaatca tgaaagtgct cggctggctc
    28141 gatggcggat cgtcggcgat ggacgatatc aagtccgggt cctcattcct gaataatgac
    28201 gtccagaccg atgccggcgg aaaccacttc gtaaaaggcg gtctcagcga tccgaacacg
    28261 ccagcagcgt caaaatggct ggcccgccat ctgtacagct tgaccgggac ggccccttct
    28321 gagtacgacc agtattttct ggatgcagcc aagaaatata acgtcgaccc gcgctggctt
    28381 aaagccatcg ccgcggggga atcttcatgg gaccagaatg cgcaagggcc tgttacacgt
    28441 tctggtaagc gtgcattagg cttaatgcaa attatgcctg ataactttca gcctggtgag
    28501 aagccgtttg acccgcggga caacatcatg gctggcgccc gagttttctc ctgggcgatg
    28561 cagagcgcga atggtgatat cgacgaagcg ctgcgttatt acaacggcgg aagccgccgc
    28621 ggtagtgcag aaaatagggc ttatcccggc aggatcaggg aaaagtatgc tgcgatgtat
    28681 ggagcgccga agaacaatga cgcttctggc gtcgatagtt cagagattgc caaaaatacc
    28741 tcgaaaacta accagctcct gcaacagatc gtagatggga aaggcggcag aggcgggagc
    28801 ggtgacgttg ttatttataa caacaccggc gggaatgccg tggtaacttc agcgcaattg
    28861 ggggcgaggt aatgggattc acacgtgaaa tgtataagct gggttttgaa atatccccag
    28921 taatactttg cggagggata gcgcaggcca ttcctggcgg aatgctcccg atcgtcgctt
    28981 tgacgcagag cgcgagcttt gttacggggc tgcttggagg agccataaac ctaaccgatc
    29041 tggataaata tttctgccac tggcgtccgg ttcagggcgc cacaatggtt gattatgaaa
    29101 ttgccagata ccctttcgcc aaccaggttg tagctgcgaa cgctttgctt gctcagcctt
    29161 tgcgcgtttc gttggtgatg gaggctccgg tcaatgaaaa ctccggggcg atgacaaagc
    29221 tcgtcactat gagtgctttg cagtctgtcc ttcaggcgca ttctaactta ggcggcacgt
    29281 ttatcgtcgc caccccatcc gttatctata gcaactgcat tttgcgtgta gtgagggaca
    29341 ttacctctgg taacgatcca ttaccacagc gttcatggat atgggatttc gagcagccac
    29401 tgataaccga taatggtgca gagcaggccg tgaacaattt tttaaacaag attggcgccg
    29461 gggatatggt aaccgaccca tcctggacta ataccgccaa tgctcttggc aacacgcctc
    29521 tcgggagctc tgtatcggaa gcaataaccg gcctattggg taagttgggg gtagggccat
    29581 gacaacccag aattatccgt ttaccggcaa tgatcgtcaa agcatgacat ttacaccgat
    29641 ccttgatggc accgtctata actgccaggt taaatggaac attgccgggc tgaggtggta
    29701 tgtcctcatt acagatagct ctgggaatac cattctaaat accccgctcg ttggctcaga
    29761 gcttaacggt ggaataaata ttatctccgg agtgtttaat tcgtcctcca tgtactggcg
    29821 cgaacagaat ggactgattg aggtaaacag ttcatgagat attatgatat tgagataacc
    29881 attcctgctg aaggtgcctc tccggaaaga acgataaaat acagtagcca taagaacgga
    29941 gtttacaacc ccggcgccct gatgattgag tttgatatcc tcaggtacgg tgaatcgact
    30001 ccccagggcg aaactcacct gaccatctgg ggtattggcc caaaagaaat gcagcaggct
    30061 cgccagaatt tttttggcaa aaaaattaaa atattccttg ggatgaaaga cgggctgcca
    30121 ttggctggca aggttaccgc accaaaactg gtattggatg gcgtgataaa tcaggtcttt
    30181 ggtaactggc agggtattga gttacgactt gacttcataa tcgttgttgg tcctgtccag
    30241 aacgtaccaa ataacaaacc cgtacccctt cctttaacct ttgactggaa ggaggggcag
    30301 aagctttctg tagccctcac gcagtgtttt atgaacatca gagggtatac gttcaatatc
    30361 aacataagcg accggctaat ccttaatcat taccgggggc tgttttgtga tgacattgtc
    30421 accctggcca aggaccttaa tgctttttca cgttccagaa ttcgcgatag cgggtactct
    30481 ggtgtagaga tcgcaatagt gaatggtaat gagatccggg tatgggataa cgattatgat
    30541 aaccacccgg ataagacttc tgtttccagc gccgtagcca gaagcaacag cccaacccaa
    30601 atagatttca aggatttgat agggcagccg acatgggtgg catttaacac aatcagcatg
    30661 gcgtgcgtaa tgcgcggtga tattcaggtt ggcgatcaca tcctgatgcc taaaaaaagc
    30721 actccgttga taaaggcctc ttcgtactct cagtatcgag aagactctgc ctttactggc
    30781 gactttatcg tgaactccgt tcgcctgtta ggaaatagca ggcaaccaac ggcagaagca
    30841 tgggtaacaa ttattgaagc ttcacctttc attaaggcag gtaatgcatg agcatcgaca
    30901 acaagcttaa ttttgcctca agcatgaaca ggtttactga aagaaagatt gaaaatgcgc
    30961 ttcaaaaatc agggaaagtt cttccggcga gcgtggttaa gcaaactggg aatatgatca
    31021 ccgtctcctt cgagctaagg gatatcccat atgttttgcc gcaagtgact atccccttat
    31081 ttggccctca atatattcgt taccctatgc agccgggaga taaggggatt gttatccccg
    31141 cagatactta cattggcggc gttagcggtc agggaggcgg cattgcagat atgactccgc
    31201 cagcaaactt aagcgccctc gttttcttgc cgatcagtaa taccgagtgg cagggtgtcg
    31261 acggacaggt ggtgacggta tacgggccgg agggtgtaac gctgcgcgac agtggcagca
    31321 acacgacgtt tctcctgaag cctgacagca tcgccatttc cacacctgac agcttcactg
    31381 taactgttgg cgggacagtt ttctcactga cgggtagcaa atggagcctt tcaggccagg
    31441 ctggtcatct gcaggattca gtggccagta ccagccctgc aatcatgcac gccgggtggc
    31501 agtcgcttct gacctggctt aacagccatg aacattcaaa cggcaacgat ggaaatgata
    31561 ccggggggcc gacttcaacg tttaacggga gtatcaccga gtgagaacct atggccgaaa
    31621 ctctgagggg aagtgggtcc tggtggaaac cgacgaaaat gggtttaatg actcggtgta
    31681 tttaaccacc ctgatccaga atctgaaact ggcgccgcag gagtcaccct tttatgcgaa
    31741 caacggaata ccggccgccg ggtcggtgat ccagcaaatc ctgccgacgt attacgtaaa
    31801 ccgtattcaa aaacagttca gccagtattt ttcctcgcta cagattgcac tgatcagcga
    31861 cgacccgcct gtttataaca tctcggcaat cacaaacgca ggttcaaaaa taattacaca
    31921 ggtggccgta tgagcgattt accagtcagc tatacgtcag caggcccggt tcctctgacg
    31981 ccggaagagc taagagcaca gctcgtttct caggcaattg cgctatctcc gggactcaca
    32041 actgatttgc ctggatctct gattgaggac gtggccagta ccgatgtcgg cgcgctcatc
    32101 gtttgtgatc aagcaagggt tgacctgatt aactcggtgg ggccactaaa ggctaacctg
    32161 gccatgctgg agcttctcgc acagcaggct ggtatccctg ggcagaaaac ggctggcaca
    32221 acaacagtcc cggttcagtt ttccggcccc gcgggatttg ttatcccaca ggggtttatt
    32281 gtttctgatg ggacctatac ctattcagtc agtgatgcga cgattatctc gtcgtctgga
    32341 gtatctgcca gcgtatcatg cgagggaacg gagaccggga cctgggcggt gccggtaaat
    32401 acggttaacc agatcatatc cagtctaccg tctgacgtca ccatcacctg caccaacccg
    32461 atcgccggca ctccgggtgc tgacccggaa acgaattatc agtttcgtga tcgagtatgg
    32521 caggctcaga tggccacagt tcagggatat cctggattta tccggcaaca tctcaccagc
    32581 cttgataacg tgcaggcgcg cctggtttct gtcattcagg acggggataa gtggatagtc
    32641 atgtgcgccg gcggtgatat ttacgatatt gctggtgcgc tctataagtc tgcgggggat
    32701 atcagccggc tgaaagggtg ttcactgaat gtaactggga tcacgaatgc aaatcctggc
    32761 gtcgtcagca cagacctgac tcatggttac actgacggcc aggttatcag gatcactggc
    32821 gtgaccggga tgacgggcat taatgacgtt cctctgaccg tgacggtgct gtctcctcac
    32881 actttttcca tcgggattga caccacgtca tccgggacct ggggaggcgg cggcgaggtg
    32941 acaccgaacg tcagaaacaa taccgtgacg gtgaatgact ggcctgataa ctacgtgatc
    33001 ccgttcgtga cgccattgct gcagcgggtc actgtgacgt atcagtgggg gacagaaagt
    33061 gttaactacc tgacagatgc cacggtcgcc tctctggtct cggcgcctac gattcagtat
    33121 gtgaacggca tattcgccgg gaaaccgctg aacgttaaca acctgaaaga cgcattctta
    33181 caggcgatta actcgacaat cgacatgggg ctgatcagca ctctaaacgt cgtggtcacc
    33241 atcaatggtg tgataacgcc accggatgcc gggacgaata tcatcagcgg cgataagttc
    33301 agttattttt atatcgcgtc ggatggcgtg atcgtaacag gggcgtagca tgctggacga
    33361 tatcatccgg tcgtatatgt atacgcaata caacgacgat gacaatctgc gggcgttttt
    33421 tactgcgtat aactcgatgg cgcagggcat ttatgactgg atggttaatg ccaacctgcc
    33481 gattttcatc ggtgactaca acaccggaga tcagctccga tggattgccc atggcatcta
    33541 tggcgtgttg ccgccggtga tttccagcag cgatcagcag gagataggcc catataacac
    33601 cttcgaattt aaccagctgg cattcaatga gtaccgggtg attgaccagt caaaccaggt
    33661 tgttgtctct gatgaccttt ttaagcggat catgacctgg aatttttaca agggtgacgg
    33721 cttctatttc tctatcccat ggataaagcg gcggattctg cggttcctgt tgggagtgaa
    33781 tggcacagac atcctcaacg accagcgatg gagtatctcg atccagtttg tggatggtgg
    33841 tatcgtgatt tccatctata aggggcgtcg gaagtttacg cggagtgcta tctacaacgc
    33901 ttctgcctat aactccagga agtacaacca gaaggacacg gcctttgtga tcaccgagga
    33961 tttcgagttt gccatattct tcaagcaggc catggatagc ggtctgctgc acatgccgtt
    34021 ctatcagtcc atttcggtgg aaattattga ttgaagcaca atgactgtgg tgtagtattt
    34081 acctcgtcca ccacagcatg gtaaagatta aaatgaaaac ttcaattatg cttgcttttt
    34141 tatcagtttc gttgtgcgca ggaagttctt ttgcagcttc ttttgattgt aataaatcaa
    34201 aaaattttgc cgaaaaaaca atttgttctg acaagaaatt atcagaagat gatgaggttc
    34261 ttgctaaggt ttataatctt gcaaagaaag ttgcgcataa taaaaatggt ttcgataggc
    34321 tgacaaaaga tttatgggac tcaagggatt tgtgcaccga ctacaaatgc attaatgatt
    34381 ggtatgatac tgtatttgtt gcgtatgatt ctgttataaa aacaaatgca agcgatgagg
    34441 ttttgaataa tattcagaaa aaatatgatg agtcaataac gcagaagcca gcaataagca
    34501 acggagctaa aaacaaaaaa gaagctaaag attatagttt atacgattca aaagacagag
    34561 ccgcgccagt tgaacataac gcaatattat acaaagacac tccagaggca ttcgaattta
    34621 tagatacact tgttgggttt gtcagacaaa gctcttacaa atgtgactct gtaagttctt
    34681 tcatacccat ggtttcatct aatggattta cgctcgcatg taataaattc agctacaaat
    34741 atgaaattaa aaacaacggc ggaaatgtct ctgtttctgt agataattag ctcaaagccc
    34801 acgccagtgg gatttcataa ataacacatt gataacatca aacccgcttc ggcgggtttt
    34861 ttatgcctaa atccggagga gacatggcac taaccctttt ggctacaaac aacgcagaaa
    34921 gcacgctggc ttctgctatc agcgcaaccg acacgtcgct gatcgttagc gcaggaactg
    34981 gtgccgagtt ccctgatgct gtggcaggcg agagctactt tactcttaca ataattgacg
    35041 ctgctactgg ttcagaagta gaaattgtaa aagtaacatc aaaaagtggt gatgtattta
    35101 caattgagag agcccaagaa ggaactattg caaaatcatg gtctgctaat gattatgtag
    35161 caaatatgat gaccgcagga acattgaatg taatttcgga cttaacaaat caggccgctc
    35221 aatcagtaga agaaatatct aatatagcag caactctccc tacaaatgaa caatttacag
    35281 aattgcaaac gtctgttgat tctattactg ccgatccagc taatgccata acttccatta
    35341 ctatacctgc actagatttc agccttgcta ttggaagcgc tagctttgga atgatcgcta
    35401 gcaggcttgc aggatggcag tttactcatg gcgcagatgc atcagttacc aaaatgatag
    35461 acctaccatc tcactggtca aaaatgcgta tttctcttat ttgggcgaat cttgtcgcga
    35521 ataccgggaa cgtaagtttt tcagggttaa tacagagttg gtcggccggg gaatcattta
    35581 atcaaactcc atcaggagga ggaactgtag ctgctgccaa cgccacgccg tatataggga
    35641 ttgaaacgca aatacccttt gatctaacag tggacccaac acggcacacc accattcgcg
    35701 taggtagaaa cggctcctcg tcaagcgata cgctcccaac agcaatggtg ttattagccg
    35761 taaggctaat taaggtggca taaatgagcg taactcaaac gtggcgcact ggaattccaa
    35821 cgccgggggt cttgcgtaac tatccaccta acccgctata tgtagattcc gtaaatggta
    35881 gcccttcagg gacgggctct gttgataatc cagttaatac attatctctc gctctaggtt
    35941 tatgcgcagg gcttcctgat tacgaaataa aaatatccgc gccagaaaat agccctttgc
    36001 gacaagaggt tatttttgac acgtcattag atgtgacttt atccggtgta gatagtgaac
    36061 cgtggtatac gttcggttcg gaaaaacaca tatcaggatg gactcagagc gggcaaattt
    36121 ggcgcaaaac gcttggctat acatctgtgc tccaggccgt cgtcacgacg atggcggaga
    36181 cagtcggcga tcgtgatgat ttctttttca aattggtaca gaacacagcc acaccaacga
    36241 caccggctgc aggtgaatat ggatattcag gcggggttat ttatgtccgt ttgcccgatg
    36301 attccagtcc taatctgcac actatagaga tatcccggcg taactttggg gttggaacaa
    36361 ttggtttcgg cctgctgaca gtaaacgact gcgtagccag atattgcatg attaacggta
    36421 tttcatgtgg tcaatcgact cagcctgccg gaactggtta tcttactgta aataactcac
    36481 ttattgaata ttgcgcaaat ggtggcgtag gcggtacggg ccgaaatgaa cttatcatct
    36541 gcaacaatgt aaaagcgtac aggataagta atgacggatt taaccagcat gctccgactg
    36601 gtggccaagg gaagatgatc cttaatggtt gcgatggaag ctataacgga gataaggcag
    36661 gtcaatcagc tcagggcgca tccaatcatg agacaacgac aatgatatta aatggaggaa
    36721 catttaattt taatgtctca ggtggaatgg tcgttattga taatgcccgc tgtgatattc
    36781 atggcgacac gcaatatggt cctgtaatga tgaatggaaa catgcgactt ggtaataccg
    36841 caggaacaat tgccaatcag ggcggttgcg catggcttaa taactcagtt ggcactgtaa
    36901 cggggtctgt tactgtagaa aacggcggcg gtgtaggcgt caggagagat tctggggctg
    36961 tagttgatgg aataacaacc atccattcaa taaataacgc attaccagac attttgtgag
    37021 gtgaaaatga cagtttgcag gttatgccag gccgaaccca tgttaatgac aaagccggaa
    37081 actgacgggg tgatcagctt ttatgtttac tatgttgaat gctccgggtg cggagtgggc
    37141 accaaaagat tttctgagca gtccttaact gcagatgagg ccattcagaa cgcacaaggc
    37201 caatgggagc taatgaacaa ggtcgatcct taaaagccgt ttcgcttgac gtgtggaatc
    37261 gataaaacta ctgtataaaa aaacagtgtt tatcggaggg aagatcatgc ttcgacagtc
    37321 agacattgcc gcggctttcc gtgagtcggt attgcgcagt tccaagggtt tccagtacct
    37381 tcacccccaa gacttcgtta ccgcgctgcg ccggcgcggc atccactttt ccgaggtgga
    37441 ggcgaactcc tggatcgcgc gggaacaaac gtatttcgtc gacaaaacgc cggaccatag
    37501 cgaaaacagg ctgtggatga tggccaacat ggggagggtc atctgatggg gttcccgtct
    37561 ccggcgtctg actacgttga gcagcgtctg tctgttaact cgatctgcaa tgtcggtcca
    37621 aatacgctcg tcttcgagca atctggtggt tacgttgtgc tggatatctc catgaagcca
    37681 aagcaaggta gtcaggttct gatccggcac ggcggtggga cggagcttgc cacgctgaga
    37741 ggaaagtcgc tgattaccga agatggtgaa gcgatcgagg gcgaagccct ggacgatgtt
    37801 actgtcatcg gcgtcgtgac gtttactatc tgcgacgttc gttctgataa ttctattatt
    37861 taactggggt atatatggcg ctgaagctat tagccaataa taacgcaaag agtgttctcg
    37921 ctgcgggtat tagcgcgtcc gctactgtta ttaccgtggg aactggagcg ggggctttat
    37981 tcccttcccc tgtatctgga cagagttatt tcaaattaac gataaccgac gcggccacga
    38041 aaacaatttc tgaaattatg cacgtcacgt ctgtatctgg tgacgtgatg acagtaattc
    38101 gtggtcagga aggaactacg gcacgtgtat ggtcaacgaa tgacattgtc gcgaatttaa
    38161 tgaccgccgg gtcattattg tctttcctgc agatcagcaa taacctgtca gaaattaaag
    38221 atgccggtga ggatgcggta aatgaagccc gttataacct tgggatcgct gattcctctg
    38281 gttttgtcgg gcgttcactt ggcgctccaa aagctttcta tgcaaacgga acctatacgc
    38341 gatctcctct ggcccgttat gcaaaagtaa cgttgaccgg tgccggtggc ggcggtggag
    38401 gctgccaggc ctccaacaat acagaaacct tctccggtgc cggcggcggt gcaggtgcga
    38461 ccattgtcgt atgggttgac ctgtctgctg ccagttctta tgcgattact gtcggcaagg
    38521 gtggtaaggg aggcgttggc gcagtaagcg gttcggatgg cggcacaacc tcgttcgcca
    38581 gcctgttctc agcaccaggt ggcaagggcg gcgtgaagtc aggcgtttcc aatactgccg
    38641 gaggcgccgg aggtacggcg gcggccggag atatcaggat caacggtggc accggctcag
    38701 atggccagac agggtccagc cttctgacgg gtaacggtgg ggcgtcgtat tttggcggcg
    38761 gtggccgggc gggttctcag gccggtattg ctggcgcagc tcccggctcc ggtggtggtg
    38821 gagcgtatga ccttgggttt accagtacgg cttataccgg cggcgatggc gcggatggca
    38881 tcctgatcct ggaagaattc gcgtaatggc ttactctcct gcgcgaccat cgatgtaatc
    38941 agcccaccac tgcatcattt ctctgcgttt atcgagatac tgagcatggt tgtaaatccc
    39001 gcgcacagat ccgccgttgg catgtgccag ttgcacttca atagcatcag caggccattc
    39061 gtgctcgttc ataatcgtgc tgaattcatg cctgaatccg tgaccgcttt ccagaccctc
    39121 atagccgatt tgtttgatca caagtagcac cgcgttctcg cagattggct tcttcttatc
    39181 gttgcgtccg gcaaaaacaa actctgacac tggtttagtg attgagctta gcgtagtgag
    39241 aagttcaacc acctggtctg acatcgggac cacatgaatt ttgcgtccct tcatcacact
    39301 ggcgtcgatg gtgataatcc tgttttcaaa atcgacgttc ttccattgca tggaacgaag
    39361 ctctttcgtt cttagggctg tgtagcgtaa aactttggtc gcaatgagcg atacgatact
    39421 tcctgaaaat gttgccagtg ctttattgaa tgccgggatc tggtctgcag gaagaaacgg
    39481 gaagttcttc ttgcggtacc ccttcatggc gtcagcaagg tcaggtgccg ggttatattt
    39541 agccctacca gtgacaatag cgtaacggaa aacctcgccg catcttctgc gggctttgtt
    39601 ggctcgctcc attgcaccgc gatcttcaaa tctgcggatt acttccagca gttgcatcgg
    39661 ctcaatatcc tgaatttcaa ggccgccaat gataggtaaa atgtcgtcgt caaacatttt
    39721 ggcaagttca gtcgcatacc ctacagacca gacttgcttc ttgtgctcgt accattcctt
    39781 gtaaatggcg ctaaaggaat tgttgttaga cgaagccttt ttcgccttta ccggatcgat
    39841 gccaaccgag atgtctttcc tcgcagtcca tgccttatcc cttgcctcct gcaaagtcat
    39901 aagtggatat tttccgacgg tcaggatttt ctccttaccg tcaatcttgt agcgaagctg
    39961 ccataccttt ttccctgaca cagggacata aaggtacagg ccattaccat cgagtaggcg
    40021 gtatggtttt tctttcggct ttgctgcttc aatctgctta acggtgagca tgggtaaaaa
    40081 tccggtgggt aaaattattt tatccacttt ttacccgtca tggagtgcgg ctgtcaacga
    40141 tctgacgcga accattacga actgtgaatc tacggaaggc ttgatattca ggggattttg
    40201 cggactggta cggatgggag cgaactgata aatggcgtcc cctgcaggaa tcgaacctgc
    40261 aattagccct taggaggggc tcgttatatc catttaacta agaggacaat gccgcatgag
    40321 tatacccgct aatggactgc ggggtaagta cactgccgct cgattgctta aaccctcgcc
    40381 atttatgccg ggtttttatc atttttctta atgttttccg cacgttctgc tttttggcgt
    40441 gcttctgctt tgcgcttgtt gctcatgtcg ttacgaatct gtgcatgact cattaacgcg
    40501 aagataaagg tgccgccgca gatgttcccc gctaaagtag gtagtgcgaa gggccagatg
    40561 aaatcgctcc agtgcagcgt gccgttaaac accagataga ggatttcaac agaaccgaca
    40621 acgatgtggg tggtgtcacc cagggcaata agccaggtca tcaatataat caccacaatc
    40681 tttgccgcac ccgctgcagg aaacatccat accatagtgg cgatcagcca gccggaaatg
    40741 atcgcgttgg caaacatctc gctgggggtg ttcttcatca catccatgcc gattttgaca
    40801 aatgcatcgc gagtttcttc attgaagatt ggcatatatt caaatgccca cgccgcaata
    40861 cctgtcccga gaatattacc cagcagcacg acgccccata accgcataag taagccaacg
    40921 ttgctcattg tcggtttttg catgacgggt agtaccgcag tcacggtgtt ttcggtaaat
    40981 aattgctggc gggccataat gacgataata aaaccaaagg tataaccgag attctccagc
    41041 aagaagctgc ccggcacacc ttccagttcg acatgaaata tcccttttgc cagtaatgaa
    41101 gcgcccatcg acagacccgc cgcaatggct gaccacagta gtgccattgc gtcgcgttcc
    41161 agctcttttt caccatcctg gcggatatgc tcatgaattg ccatcgcccg ggaggggagt
    41221 cgatcttcat ctatttctat ttttttgccg cgctcttttt cttcgctctc aacttcaatt
    41281 tcgtcgctgt gttgatcaat tttgtcgttg tccatggtct cttctcttga attagcacgt
    41341 atagctaaag cgtagcggct tttttgctcg caactggcgg gagttactct gaaaatgtag
    41401 aaaaggccgc gtttgccttt ttctgtttct atagaatcaa gtagcctaca gggcggcgat
    41461 taccaggcta tgatcaaatc agcaaatcag ggcgtctgga catcagttga cgtgctgtta
    41521 caatcgccca cacctaaaca ggcggatacg gtatcgttcc gtcatggatg gcaaactgca
    41581 taagccataa aaaaacaggg agacatttat gaagcttcgc ctgtcggcgc ttgctctggg
    41641 aactacgctt ctggtggggt gtgcgagttc cggtacagat cagcaagggc gttctgaccc
    41701 gttagaaggg ttcaaccgca ccatgtacaa cttcaacttc aatgtattag acccgtatat
    41761 tgttcgaccg gtcgctgtcg cctggcgtga ttatgttccg caaccggcgc gtaacggttt
    41821 gagcaacttt actggcaacc ttgaagaacc tgcggtgatg gttaactact ttttgcaggg
    41881 cgacccttat caggggatgg tccactttac ccgctttttc ctgaacacca ttttggggat
    41941 gggcggcttt attgatgttg cagggatggc gaacccgaaa ctgcaacgga ctgaacctca
    42001 ccgcttcggt agtacgcttg gtcattatgg tgtgggttat gggccatacg ttcagttacc
    42061 gttctacggt agcttcacgc tgcgtgatga cggtggtgat atggcggatg gtctttaccc
    42121 ggttctttcc tggctgacct ggccgatgtc tgtgggtaaa tggacgcttg aagggataga
    42181 aactcgtgcg cagttgttgg attccgacgg tctgctgcgt cagtcgtccg atccttatat
    42241 tatggtgcgc gaagcgtact tccagcgtca tgatttcatc gctaatggcg gcgaactcaa
    42301 accgcaggaa aatccgaacg cgcaagcgat tcaggatgat ttaaaagata tcgattctga
    42361 ataagaaaca aataaaaaag gtgagtcaca a
//
LOCUS       DADXDL010000032        40938 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.032, whole genome shotgun sequence.
ACCESSION   DADXDL010000032 DADXDL010000000
VERSION     DADXDL010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40938
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.032"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(33..329)
                     /locus_tag="IRB70_002039"
     CDS             complement(33..329)
                     /locus_tag="IRB70_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HBC0631953.1"
                     /translation="MKKMQSIVLALSLVLVAPMAAQAAEITLVPSVKLQIGDRDNRGY
                     YWDGGHWRDHGWWKQHYEWRGNRWHPHGPPPPPRHHKKAPHDHHGGHGPGKHHR"
     gene            complement(543..1829)
                     /gene="thrC"
                     /locus_tag="IRB70_002040"
     CDS             complement(543..1829)
                     /gene="thrC"
                     /locus_tag="IRB70_002040"
                     /EC_number="4.2.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine synthase"
                     /protein_id="HBC0631954.1"
                     /translation="MKLYNLKDHNEQVSFAQAVTQGLGKNQGLFFPHDLPEFSLTEID
                     EMLKLDFVTRSAKILSAFIGDEIPQEILEERVRAAFAFPAPVANVESDVGCLELFHGP
                     TLAFKDFGGRFMAQMLTHIAGDKPVTILTATSGDTGAAVAHAFYGLPNVKVVILYPRG
                     KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKVALGLNSANSINISR
                     LLAQICYYFEAVAQLPQEARNQLVVSVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
                     DTVPRFLHDGQWSPKATQATLSNAMDVSQPNNWPRVEELFRRKIWQLKELGYAAVDDE
                     TTQQTMRELKELGYTSEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVEAILGE
                     TLDLPKELAERADLPLLSHNLPADFAALRKLMMNHQ"
     gene            complement(1830..2762)
                     /gene="thrB"
                     /locus_tag="IRB70_002041"
     CDS             complement(1830..2762)
                     /gene="thrB"
                     /locus_tag="IRB70_002041"
                     /EC_number="2.7.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine kinase"
                     /protein_id="HBC0631955.1"
                     /translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGALLGDVVTVEAAETF
                     GLNNLGRFADKLPSEPRENIVYQCWERFCQELGKQIPVAMTLEKNMPIGSGLGSSACS
                     VVAALMAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENDI
                     ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
                     PELAAKLMKDVIAEPYRERLLPGFRQARQAVAEIGAVASGISGSGPTLFALCDKPDTA
                     QRVADWLGKNYLQNQEGFVHICRLDTAGARVLEN"
     gene            complement(2764..5226)
                     /gene="thrA"
                     /locus_tag="IRB70_002042"
     CDS             complement(2764..5226)
                     /gene="thrA"
                     /locus_tag="IRB70_002042"
                     /EC_number="1.1.1.3"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional aspartate kinase/homoserine
                     dehydrogenase I"
                     /protein_id="HBC0631956.1"
                     /translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
                     NHLVAMIEKTISGQDALPNISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIK
                     HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGVLEARGHNVTVIDPVEKLLAVGHY
                     LESTVDIAESTRRIAASRIPADHMVLMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
                     RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
                     QIPCLIKNTGNPQAPGTLIGASRDEDELPVKGISNLNNMAMFSVSGPGMKGMVGMAAR
                     VFAAMSRARISVVLITQSSSEYSISFCVPQSDCVRAERAMQEEFYLELKEGLLEPLAV
                     TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
                     GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQSWLKNKHIDLRVCGVANSKA
                     LLTSVHGLNLENWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
                     FLREGFHVVTPNKKANTSSMDYYHLLRHAAEKSRRKFLYDTNVGAGLPVIENLQNLLN
                     AGDELMKFSGILSGSLSYIFGKLDEGMSFSEATTLAREMGYTEPDPRDDLSGMDVARK
                     LLILARETGRELELADIEIEPVLPAEFNAEGDVAAFMANLSQLDDLFAARVAKARDEG
                     KVLRYVGNIDEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
                     NDVTAAGVFADLLRTLSWKLGV"
     misc_feature    complement(5252..5371)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00506"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Thr leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00506"
     gene            complement(5307..5372)
                     /gene="thrL"
                     /locus_tag="IRB70_002043"
     CDS             complement(5307..5372)
                     /gene="thrL"
                     /locus_tag="IRB70_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thr operon leader peptide"
                     /protein_id="HBC0631957.1"
                     /translation="MKRISTTITTTITITTGNGAG"
     gene            complement(5586..6272)
                     /locus_tag="IRB70_002044"
     CDS             complement(5586..6272)
                     /locus_tag="IRB70_002044"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA/rRNA methyltransferase"
                     /protein_id="HBC0631958.1"
                     /translation="MRITIILVAPARAENIGAAARAMKTMGFSELRIVDSQAHLEPAT
                     RWVAHGSGDVIDNIKVFPTLAESLHDVDFTVATTARSRAKYHYYATPVELVPLLEEKS
                     SWMSHAALVFGREDSGLTNEELALADVLTGVPMVADYPSLNLGQAVMVYCYQLATLIQ
                     QPAKSDTTADQHQLQALRERVMALLTTLAVADDIKLVDWLQQRLGLLEQRDTAMLHRL
                     LHDIEKNITK"
     gene            complement(6672..6812)
                     /locus_tag="IRB70_002045"
     CDS             complement(6672..6812)
                     /locus_tag="IRB70_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631959.1"
                     /translation="MTKVRNCVLDALSINVNNIISLVVGTFPQDPTVSKTAVILTILT
                     AT"
     gene            6908..7624
                     /gene="arcA"
                     /locus_tag="IRB70_002046"
     CDS             6908..7624
                     /gene="arcA"
                     /locus_tag="IRB70_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003621071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator ArcA"
                     /protein_id="HBC0631960.1"
                     /translation="MQTPHILIVEDELVTRNTLKSIFEAEGYDVFEATDGAEMHQILS
                     EYDINLVIMDINLPGKNGLLLARELREQANVALMFLTGRDNEVDKILGLEIGADDYIT
                     KPFNPRELTIRARNLLSRTMNLGTVSEERRSVESYKFNGWELDINSRSLIGPDGEQYK
                     LPRSEFRAMLHFCENPGKIQSRAELLKKMTGRELKPHDRTVDVTIRRIRKHFESTPDT
                     PEIIATIHGEGYRFCGDLED"
     gene            complement(7683..9035)
                     /gene="creD"
                     /locus_tag="IRB70_002047"
     CDS             complement(7683..9035)
                     /gene="creD"
                     /locus_tag="IRB70_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein CreD"
                     /protein_id="HBC0631961.1"
                     /translation="MLKSPLFWKMTTLFGAVLLLLIPIMLIRQVIVERADYRSDVEDA
                     IRQSTSGPQKLVGPLIAIPVTELYTVQEEDKTVERKRSFIHFWLPESLMVDGNQNVEE
                     RKIGIYTGQVWHSDLTLKADFDVSRLSELNAPNIILGKPFIVISVGDARGIGVVKAPE
                     VNGTALTIEPGTGLEQGGQGVHIPLPEGDWRKQNLQLNMALNLSGTGDLSVVPAGRNS
                     EMTLTSNWPHPSFLGDFLPAKREVSESGFQAQWQSSWFANNLGERFASGNDTGWENFP
                     AFSVAVTTPADQYQLTDRATKYAILLIALTFMAFFVFETLTAQRLHPMQYLLVGLSLV
                     MFYLLLLALSEHTGFTVAWIIASLIGALMNGIYLQAVLKGWRNSMLFTLALLLLDGVM
                     WGLLNSADSALLLGTSVLVVALAGMMFVTRNIDWYAFSLPKMKASKEVTTDDELRIWK
                     "
     gene            complement(9093..10517)
                     /gene="creC"
                     /locus_tag="IRB70_002048"
     CDS             complement(9093..10517)
                     /gene="creC"
                     /locus_tag="IRB70_002048"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     CreC"
                     /protein_id="HBC0631962.1"
                     /translation="MRIGMRLLLGYFLLVAVAAWFVLAIFVKEVKPGVRRATEGTLID
                     TATLLAELARPDLLSGDPTHGQLAQAFNQLQHRPFRANIGGINKVRNEYHVYMTDAQG
                     KVLFDSANKAVGQDYSRWNDVWLTLRGQYGARSTLQNPADPESSVMYVAAPIMDGSRL
                     IGVLSVGKPNAAMAPVIKRSERRILWASAILLGIALVIGAGMVWWINRSIARLTRYAD
                     SVTDNKPVPLPDLGSSELRKLAQALESMRVKLEGKNYIEQYVYALTHELKSPLAAIRG
                     AAEILREGPPPEVVARFTDNILTQNARMQALVETLLRQARLENRQEVVLTAVDVAALF
                     RRVSEARTVQLAEKNITLHVTPTEVNVAAEPALLDQALGNLLDNAIDFTPESGRITLS
                     AEVDQEHVTLKVLDTGSGIPDYALSRIFERFYSLPRANGQKSSGLGLAFVSEVARLFN
                     GEVTLRNVQAGGVLASLRLHRHFT"
     gene            complement(10517..11206)
                     /gene="creB"
                     /locus_tag="IRB70_002049"
     CDS             complement(10517..11206)
                     /gene="creB"
                     /locus_tag="IRB70_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator CreB"
                     /protein_id="HBC0631963.1"
                     /translation="MQRETVWLVEDEQGIADTLVYMLQQEGFAVEVFERGLPVLDKAR
                     QQVPDVMILDVGLPDISGFELCRQLLALHPALPVLFLTARSEEVDRLLGLEIGADDYV
                     AKPFSPREVCARVRTLLRRVKKFSTPSPVIRIGHFELNEPAAQISWFDTPLTLTRYEF
                     LLLKTLLKSPGRVWSRQQLMDSVWEDAQDTYDRTVDTHIKTLRAKLRAINPDLSPINT
                     HRGMGYSLRGL"
     gene            complement(11219..11692)
                     /gene="creA"
                     /locus_tag="IRB70_002050"
     CDS             complement(11219..11692)
                     /gene="creA"
                     /locus_tag="IRB70_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein CreA"
                     /protein_id="HBC0631964.1"
                     /translation="MKYKHLILSLSLIMLGPLAHAEEIGSVDTVFKMIGPDHKIVVEA
                     FDDPDVKNVTCYVSRAKTGGIKGGLGLAEDTSDAAISCQQVGPIELSDRIKNGKAQGE
                     VVFKKRTSLVFKSLQVVRFYDAKRNALAYLAYSDKVVEGSPKNAISAVPVMPWRQ"
     gene            11903..12772
                     /gene="robA"
                     /locus_tag="IRB70_002051"
     CDS             11903..12772
                     /gene="robA"
                     /locus_tag="IRB70_002051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     RobA"
                     /protein_id="HBC0631965.1"
                     /translation="MDQAGIIRDLLIWLEGHLDQPLSLDNVAAKAGYSKWHLQRMFKD
                     VTGHAIGAYIRARRLSKSAVALRLTARPILDIALQYRFDSQQTFTRAFKKQFAQTPAL
                     YRRSPEWSAFGIRPPLRLGEFTMPEHKFVTLEDTPLIGVTQSYSCSLEQISDFRHEMR
                     YQFWHDFLGNAPTIPPVLYGLNETRPSQDKDDEQEVFYTTALAQDQADGYVLTGHPVM
                     LQGGEYVMFTYEGLGTGVQEFILTVYGTCMPMLNLTRRKGQDIERYYPAEDAKAGDRP
                     INLRCELLIPIRR"
     gene            complement(12769..13416)
                     /gene="gpmB"
                     /locus_tag="IRB70_002052"
     CDS             complement(12769..13416)
                     /gene="gpmB"
                     /locus_tag="IRB70_002052"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase GpmB"
                     /protein_id="HBC0631966.1"
                     /translation="MLQVYLVRHGETQWNAERRIQGQSDSPLTAKGEQQAMQVATRAK
                     ELGITHIISSDLGRTRRTAEIIAQACGCDIIFDSRLRELNMGVLEKRHIDSLTEEEEN
                     WRRQLVNGTVDGRIPEGESMQELSDRVNAALESCRDLPQGSRPLLVSHGIALGCLVST
                     ILGLPAWAERRLRLRNCSISRVDYQESLWLASGWVVETAGDISHLDAPALDELQR"
     gene            13468..13989
                     /gene="yjjX"
                     /locus_tag="IRB70_002053"
     CDS             13468..13989
                     /gene="yjjX"
                     /locus_tag="IRB70_002053"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001649724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inosine/xanthosine triphosphatase"
                     /protein_id="HBC0631967.1"
                     /translation="MHQVVCATTNPAKIQAILQAFHEIFGEGSCHIASVAVESGVPEQ
                     PFGSEETRAGARNRVANARRLLPEADFWVAIEAGIDGDSTFSWVVIENASQRGEARSA
                     TLPLPAVILEKVREGEALGPVMSRYTGIDEIGRKEGAIGVFTAGKLTRASVYHQAVIL
                     ALSPFHNAVYQAL"
     gene            complement(14074..14400)
                     /gene="trpR"
                     /locus_tag="IRB70_002054"
     CDS             complement(14074..14400)
                     /gene="trpR"
                     /locus_tag="IRB70_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon repressor"
                     /protein_id="HBC0631968.1"
                     /translation="MAQQSPYSAAMAEQRHQEWLRFVDLLKNAYQNDLHLPLLNLMLT
                     PDEREALGTRVRIVEELLRGEMSQRELKNELGAGIATITRGSNSLKAAPVELRQWLEE
                     VLLKSD"
     gene            complement(14490..16427)
                     /gene="sltY"
                     /locus_tag="IRB70_002055"
     CDS             complement(14490..16427)
                     /gene="sltY"
                     /locus_tag="IRB70_002055"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase"
                     /protein_id="HBC0631969.1"
                     /translation="MEKAKQVTWRLLAAGVCLLTVSSVARADSLDEQRSRYAQIKQAW
                     DNRQMDVVEQMMPRLKDYPLYPYLEYRQITDDLMNQPAVTVTNFVRANPTLPPARTLQ
                     SRFVNELARREDWRGLLAFSPEKPGTTEAQCNYYYAKWNTGQSEEAWQGAKELWLTGK
                     SQPNACDKLFSVWRASGKQDPLAYLERIRLAMKAGNTGLVTVLAGQMPADYQTIASAI
                     ISLANNPNTVLTFARTTGATDFTRQMAAVAFASVARQDAENARLMIPSLAQAQQLNED
                     QIQELRDIVAWRLMGNDVTDEQAKWRDDAIMRSQSTSLIERRVRMALGTGDRRGLNTW
                     LARLPMEAKEKDEWRYWQADLLLERGREAEAKEILHQLMQQRGFYPMVAAQRIGEEYE
                     LKIDKAPQNVDSALTQGPEMARVRELMYWNLDNTARSEWANLVKSKSKTEQAQLARYA
                     FNNQWWDLSVQATIAGKLWDHLEERFPLAYNDLFKRYTSGKEIPQSYAMAIARQESAW
                     NPKVKSPVGASGLMQIMPGTATHTVKMFSIPSYSSPGQLLDPETNINIGTSYLQYVYQ
                     QFGNNRIFSSAAYNAGPGRVRTWLGNSAGRIDAVAFVESIPFSETRGYVKNVLAYDAY
                     YRYFMGDKPTLMSATEWGRRY"
     gene            16638..18305
                     /gene="ettA"
                     /locus_tag="IRB70_002056"
     CDS             16638..18305
                     /gene="ettA"
                     /locus_tag="IRB70_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017145039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-dependent translational throttle protein
                     EttA"
                     /protein_id="HBC0631970.1"
                     /translation="MAQFVYTMHRVGKVVPPKRHILKNISLSFFPGAKIGVLGLNGAG
                     KSTLLRIMAGIDKDIEGEARPQPDIKIGYLPQEPQLNPEHTVRESIEEAVSEVVNALK
                     RLDEVYALYADPDADFDKLAAEQGRLEEIIQAHDGHNLNVQLERAADALRLPDWDAKI
                     ANLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAESVAWLERFLHDFEGTVVAITHD
                     RYFLDNVAGWILELDRGEGIPWEGNYSSWLEQKDQRLAQEASQEAARRKSIEKELEWV
                     RQGTKGRQSKGKARLARFEELNSTEYQKRNETNELFIPPGPRLGDKVLEVSNLRKSYG
                     DRLLIDDLSFSIPKGAIVGIIGPNGAGKSTLFRMISGQEQPDSGTITLGETVKLASVD
                     QFRDSMDNSKTVWEEVSGGLDIMKIGNTEMPSRAYVGRFNFKGVDQGKRVGELSGGER
                     GRLHLAKLLQVGGNMLLLDEPTNDLDIETLRALENALLEFPGCAMVISHDRWFLDRIA
                     THILDYQDEGKVEFFEGNFTEYEEYKKRTLGADALEPKRIKYKRIAK"
     gene            complement(18412..18579)
                     /locus_tag="IRB70_002057"
     CDS             complement(18412..18579)
                     /locus_tag="IRB70_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000007434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631971.1"
                     /translation="MSFFDELKTSLEEAVEIKQGLKKPARVTRHEIEDAKAVVDRKRC
                     SRRIRHSVLNA"
     gene            complement(18613..19845)
                     /gene="nadR"
                     /locus_tag="IRB70_002058"
     CDS             complement(18613..19845)
                     /gene="nadR"
                     /locus_tag="IRB70_002058"
                     /EC_number="2.7.1.22"
                     /EC_number="2.7.7.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463436.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional transcriptional
                     regulator/nicotinamide-nucleotide
                     adenylyltransferase/ribosylnicotinamide kinase NadR"
                     /protein_id="HBC0631972.1"
                     /translation="MSSFDYLKTAIKQQGCTLQQVADASGMTKGYLSQLLNAKIKSPS
                     AQKLEALHRFLGLEFPRQKKTIGVVFGKFYPLHTGHIYLIQRACSQVDELHIIMGFDD
                     TRDRALFEDSAMSQQPTVPDRLRWLLQTFKYQKNIRIHAFNEEGMEPYPHGWDVWSNG
                     IKKFMAEKGIQPDLIYTSEEADAPQYMEHLGIETVLVDPKRTFMSISGAQIRENPFRY
                     WEYIPTEVKPFFVRTVAILGGESSGKSTLVNKLANIFNTTSAWEYGRDYVFSHLGGDE
                     IALQYSDYDKIALGHAQYIDFAVKYANKVAFIDTDFVTTQAFCKKYEGREHPFVQALI
                     DEYRFDLVILLENNTPWVADGLRSLGSSVDRKEFQNLLVEMLEENNIEFVRVEEDDYD
                     SRFLRCVELVREMMGEQG"
     gene            complement(19866..21248)
                     /gene="radA"
                     /locus_tag="IRB70_002059"
     CDS             complement(19866..21248)
                     /gene="radA"
                     /locus_tag="IRB70_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001399683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBC0631973.1"
                     /translation="MAKAPKRAFVCNECGADYPRWQGQCSACHAWNTITEVRLAASPT
                     VARNERLSGYAGSAGVAKVQKLSDISLEELPRFSTGFKEFDRVLGGGVVPGSAILIGG
                     NPGAGKSTLLLQTLCKLAQQMKTLYVTGEESLQQVAMRAHRLGLPTDNLNMLSETSIE
                     QICLIAEEEQPKLMVIDSIQVMHMADIQSSPGSVAQVRETAAYLTRFAKTRGVAIVMV
                     GHVTKDGSLAGPKVLEHCIDCSVLLDGDADSRFRTLRSHKNRFGAVNELGVFAMTEQG
                     LREVSNPSAIFLSRGDEVTSGSSVMVVWEGTRPLLVEIQALVDHSMMANPRRVAVGLE
                     QNRLAILLAVLHRHGGLQMADQDVFVNVVGGVKVTETSADLALLLAMVSSLRDRPLPQ
                     DLVVFGEVGLAGEIRPVPSGQERISEAAKHGFRRAIVPAANVPKKAPEGMQIFGVKKL
                     SDALSVFDDL"
     gene            complement(21297..22265)
                     /gene="serB"
                     /locus_tag="IRB70_002060"
     CDS             complement(21297..22265)
                     /gene="serB"
                     /locus_tag="IRB70_002060"
                     /EC_number="3.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoserine phosphatase"
                     /protein_id="HBC0631974.1"
                     /translation="MPNITWCDLPEDVSLWPGLPLSLSGDEVMPLDYHAGRSGWLLYG
                     RGLDKQRLTQYQSKLGAAMVIVAAWCVEDYQVIRLAGSLTARATRLAHEAQLDVAPLG
                     KIPHLRTPGLLVMDMDSTAIQIECIDEIAKLAGTGEMVAEVTERAMRGELDFTASLRS
                     RVATLKGADANILQQVRENLPLMPGLTQLVLKLETLGWKVAIASGGFTFFAEYLRDKL
                     RLTAVVANELEIMDGKFTGNVIGDIVDAQYKAKTLTRLAQEYEIPLAQTVAIGDGAND
                     LPMIKAAGLGIAYHAKPKVNEKAEVTIRHADLMGVFCILSGSLNQK"
     gene            22371..23015
                     /locus_tag="IRB70_002061"
     CDS             22371..23015
                     /locus_tag="IRB70_002061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtjB family periplasmic protein"
                     /protein_id="HBC0631975.1"
                     /translation="MARTKLKFRLHRAVIVLFCLALLVALMQGASWFSQNHQRQRNPQ
                     LEELARTLARQVTLNVAPLMRTDSPDEKRIQAILDQLTDESRILDAGVYDEQGDLIAR
                     SGESVEVRDRLALDGKKAGGYFNQQIVEPIAGKNGPLGYLRLTLDTHTLATEAQQVDN
                     TTNILRLMLLLSLAIGVVLTRTLLQDKRTRWQQSPFLLTASKPVPEEEESEKKE"
     gene            23043..24059
                     /gene="lplA"
                     /locus_tag="IRB70_002062"
     CDS             23043..24059
                     /gene="lplA"
                     /locus_tag="IRB70_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase LplA"
                     /protein_id="HBC0631976.1"
                     /translation="MSTLRLLISDSYDPWFNLAVEECIFRQMPATQRVLFLWRNADTV
                     VIGRAQNPWKECNTRRMEEDNVRLARRSSGGGAVFHDLGNTCFTFMAGKPEYDKTIST
                     SIVLNALNALGVSAEASGRNDLVVKTAEGDRKVSGSAYRETKDRGFHHGTLLLNADLS
                     RLANYLNPDKKKLAAKGITSVRSRVTNLTELLPGITHEQVCEAISETFFAHYGERTEA
                     EIISPDKTPDLPNFAETFARQSSWEWNFGQAPAFSHLLDERFTWGGVELHFDVEKGHI
                     TRTQVFTDSLNPAPLEALAGRLQGCLYRADMLQQECEALLVDFPEQEKELRELSAWIA
                     GAVR"
     gene            complement(24060..25391)
                     /gene="yjjJ"
                     /locus_tag="IRB70_002063"
     CDS             complement(24060..25391)
                     /gene="yjjJ"
                     /locus_tag="IRB70_002063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HipA family toxin
                     YjjJ"
                     /protein_id="HBC0631977.1"
                     /translation="MSELTDLLLQGPRSAPELRQRLAISQATFSRLVAREDRVIRFGK
                     ARATRYALLRPYRGIERIPVWRVDDAGKAHKFADIQLCWPQGSCLVTGGKGDEQWFDG
                     LPWYLTDLRPQGFLGRAWGRNLAGQLNLTEDIRLWQEEDVLYALTVFNGEYTGGWLVG
                     ERNYQRWITAPRPAAIPLDQKLTRYEQLAHDALAGEIVGSSAGGEQPKFTCYVQTPSG
                     NKHVLVKFTVPQQTAVSQRWGDLLIAESIAAQILCDGGIHAIESTVLVTSNRQVFLEA
                     ERFDCKGNDGRLPIVSLEAVQSEFISSPGSWPEAMRRLCEQQFVTHQSVAQTEVIWAF
                     GRLIANSDMHAGNLSFYLSEPPFALTPVYDMLPMAYAPNIAGMLRDAAIEVKFDLNVS
                     KSAWLTAIPLAQQFWQTVAGDPRISEAFRHIAQEMPEKIRQIEGKVARMGG"
     gene            complement(25558..26277)
                     /gene="deoD"
                     /locus_tag="IRB70_002064"
     CDS             complement(25558..26277)
                     /gene="deoD"
                     /locus_tag="IRB70_002064"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBC0631978.1"
                     /translation="MATPHINAEMGDFADVVLMPGDPLRAKYIAETFLEDAREVNNVR
                     GMLGFTGTYKGRKISVMGHGMGIPSCSIYTKELITDFGVKKIIRVGSCGAVLPHVKLR
                     DVVIGMGACTDSKVNRIRFKDHDFAAIADFDMVRNAVDAAKALGIDARVGNLFSADLF
                     YSPDGEMFDVMEKYGILGVEMEAAGIYGVAAEFGAKALTICTVSDHIRTHEQTTAAER
                     QTTFNDMIKIALESVLLGDKE"
     gene            complement(26334..27557)
                     /gene="deoB"
                     /locus_tag="IRB70_002065"
     CDS             complement(26334..27557)
                     /gene="deoB"
                     /locus_tag="IRB70_002065"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBC0631979.1"
                     /translation="MKRAFIMVLDSFGIGATEDAERFGDVGADTLGHIAEACAKGEAD
                     NGRKGPLNLPNLTRLGLAKAHEGSTGFIPAGMDGNAEVIGAYAWAHEMSSGKDTPSGH
                     WEIAGVPVLFEWGYFSDHENSFPQELLDKLVERANLPGYLGNCHSSGTVILDQLGEEH
                     MKTGKPIFYTSADSVFQIACHEETFGLDKLYELCEIAREELTNGGYNIGRVIARPFIG
                     DKAGNFQRTGNRHDLAVEPPAPTVLQKLVDEKHGQVVSVGKIADIYANCGITKKVKAT
                     GLDALFDATIKEMKEAGDNTIVFTNFVDFDSSWGHRRDVAGYAAGLELFDRRLPELMS
                     LLRDDDILILTADHGCDPTWTGTDHTREHIPVLVYGPKVKPGSLGHRETFADIGQTLA
                     KYFGTSDMEYGKAMF"
     gene            complement(27609..28931)
                     /gene="deoA"
                     /locus_tag="IRB70_002066"
     CDS             complement(27609..28931)
                     /gene="deoA"
                     /locus_tag="IRB70_002066"
                     /EC_number="2.4.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313368.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine phosphorylase"
                     /protein_id="HBC0631980.1"
                     /translation="MFLAQEIIRKKRDGHALSDEEIRFFINGIRDNTISEGQIAALAM
                     TIFFHDMTMPERVSLTMAMRDSGTVLDWKSLHLNGPIVDKHSTGGVGDVTSLMLGPMV
                     AACGGYIPMISGRGLGHTGGTLDKLESIPGFDIFPDDNRFREIIKDVGVAIIGQTSSL
                     APADKRFYATRDITATVDSIPLITASILAKKLAEGLDALVMDVKVGSGAFMPTYELSE
                     ALAEAIVGVANGAGVRTTALLTDMNQVLASSAGNAVEVREAVQFLTGEYRNPRLFDVT
                     MALCVEMLTSGKLAKDDAEARAKLQAVLDNGKAAEVFGRMVAAQKGPTDFVENYAKYL
                     PTAMLTKAVYADTEGFVSDMDTRALGMAVVAMGGGRRQASDTIDYSVGFTDMARLGDQ
                     VDGQRPLAVIHAKDENSWQEAAKAVKAAIKLADKAPESTPTVYRRISE"
     gene            complement(29098..29877)
                     /gene="deoC"
                     /locus_tag="IRB70_002067"
     CDS             complement(29098..29877)
                     /gene="deoC"
                     /locus_tag="IRB70_002067"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005097947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBC0631981.1"
                     /translation="MTDLKASSLRALKLMDLTTLNDDDTDEKVIALCHQAKTPVGNTA
                     AICIYPRFIPIARKTLKEQGTPEIRIATVTNFPHGNDDIEIALAETRAAIAYGADEVD
                     VVFPYRALMAGNEQVGFDLVKACKEACAAANVLLKVIIETGELKDEALIRKASEISIK
                     AGADFIKTSTGKVAVNATPESARIMMEVIRDMGVEKTVGFKPAGGVRTAEDAQKYLAI
                     ADELFGADWADARHYRFGASSLLASLLKALGHGDGKSTSSY"
     gene            30136..31686
                     /locus_tag="IRB70_002068"
     CDS             30136..31686
                     /locus_tag="IRB70_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjI family glycine radical enzyme"
                     /protein_id="HBC0631982.1"
                     /translation="MPTSHENALQQRCQQIVTSPVLSPEQKRHFLALEAENNLPYPQL
                     PAEARRALDEGVICDMFEGHAPYKPRYVLPDYARFLANGSEWLELEGAKDLDDALSLL
                     TILYHHVPSVTSMPVYLGQLDALLQPYVIILTQDEIDVRIKRFWRYLDRTLPDAFMHA
                     NIGPSDSPITRAILRADAELKQVSPNLTFIYDPEITPDDLLLEVAKNICECSKPHIAN
                     GPVHDKIFTKGGYGIVSCYNSLPLAGGGGTLVRLNLKAIAERSESLDDFFTRTLPHYC
                     QQQIAIIDARCEFLYQQSHFFENSFLVKEGLINPERFVPMFGMYGLAEAVNLLCEKEG
                     IAARYGKEAAANEVGYRISAQLAEFVANTPVKYGWQKRAMLHAQSGISSDIGTTPGAR
                     LPYGDEPDPITHLQTVAPHHAYYYSGISDILTLDETIKRNPQALVQLCLGAFKAGMRE
                     FTANVSGNDLVRVTGYMVRLSDLEKYRAEGSRTNTTWLGEEAARNTRILERQPRVISH
                     EQQMRFSQ"
     gene            31658..32521
                     /locus_tag="IRB70_002069"
     CDS             31658..32521
                     /locus_tag="IRB70_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjW family glycine radical enzyme activase"
                     /protein_id="HBC0631983.1"
                     /translation="MNSRCALVSKIIPFSCVDGPGSRLALFLQGCNLRCKNCHNPWTM
                     GRCNDCGECVPQCPHQALQIVDGKVLWNAVVCEQCDTCLKMCPQHATPMAQSMSVDEV
                     LSHVRKAVLFIEGITVSGGEATTQLPFVVALFTAIKNDPQLRHLTCLVDSNGMLSETG
                     WEKLLPVCDGAMLDLKAWGSECHQQLTGRDNQQIKRSICLLAERGKLAELRLLVIPDQ
                     VDYLHHIDELATFIKRLGDVPVRLNAFHAHGVYGEAQSWASATPEDVEPLADALKVRG
                     VSRLIFPALYL"
     gene            complement(33037..33819)
                     /locus_tag="IRB70_002070"
     CDS             complement(33037..33819)
                     /locus_tag="IRB70_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBC0631984.1"
                     /translation="MICRFIDTHCHFDFPPFSGDEEASLQRAAQAGVGKIIVPATEAE
                     NFARVQALAEKYQPLYAALGLHPGMLEKHSDVSLDQLQQALERRPAKVVAVGEIGLDL
                     FGDDPQFERQQWLLDEQLKLAKRYDLPVILHSRRTHDKLAMHLKRHDLSRTGVVHGFS
                     GSLQQAERFVQLGYKIGVGGTITYPRASKTRDVIAKLPLASLLLETDAPDMPLNGFQG
                     QPNRPEQAARVFDVLCELRPEPEDEIAEVLLNNTYAVFSVRG"
     gene            complement(33816..34889)
                     /locus_tag="IRB70_002071"
     CDS             complement(33816..34889)
                     /locus_tag="IRB70_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin family protein"
                     /protein_id="HBC0631985.1"
                     /translation="MGQRIPVTLGNIAPLSLRPFQPGRIALVCEGGGQRGIFTAGVLD
                     EFMRAQFNPFDLYLGTSAGAQNLSAFICNQPGYARKVIMRYTTKREFFDPLRFVRGGN
                     LIDLDWLVEATASQMPLQMDTAARLFDSGKSFYMCACRQDDYAPNYFLPTKQNWLDVI
                     RASSAIPGFYRSGVSLEGINYLDGGISDAIPVKEAARQGAKTLVVIRTVPSQMYYTPQ
                     WFKRMERWLGDSSLQPLVNLVQHHETSYRDIQQFIEKPPGKLRIFEIYPPKPLHSIAL
                     GSRIPALREDYKLGRLCGRYFLATVGKLLTEKAPLTRHLVPVVTPESIVIPPAPVAND
                     TLVAEVIDAPQANDPTFNNEDLA"
     gene            complement(35011..35172)
                     /locus_tag="IRB70_002072"
     CDS             complement(35011..35172)
                     /locus_tag="IRB70_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002887716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1328 domain-containing protein"
                     /protein_id="HBC0631986.1"
                     /translation="MFRWGIIFLVIALIAAALGFGGLAGTAAGAAKIVFVVGIILFLV
                     SLFMGRKRP"
     gene            complement(35299..35904)
                     /gene="osmY"
                     /locus_tag="IRB70_002073"
     CDS             complement(35299..35904)
                     /gene="osmY"
                     /locus_tag="IRB70_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_710115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone OsmY"
                     /protein_id="HBC0631987.1"
                     /translation="MTMTRLKISKTLLAVMLTSAVATGSAYAENNAQTTNESAGQKVD
                     SSMNKVGNFMDDSAITAKVKAALVDHDNIKSTDISVKTDQKVVTLSGFVESQAQAEEA
                     VKVAKGVEGVTSVSDKLHVRDAKEGSVKGYAGDTATTSEIKAKLLADDIVPSRKVKVE
                     TTDGVVQLSGTVDSQAQSDRAESIAKAVDGVKSVKNDLKTK"
     gene            complement(36297..37886)
                     /gene="prfC"
                     /locus_tag="IRB70_002074"
     CDS             complement(36297..37886)
                     /gene="prfC"
                     /locus_tag="IRB70_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBC0631988.1"
                     /translation="MTLSPYLQEVAKRRTFAIISHPDAGKTTITEKVLLFGQAIQTAG
                     TVKGRGSNQHAKSDWMEMEKQRGISITTSVMQFPYHDCLVNLLDTPGHEDFSEDTYRT
                     LTAVDCCLMVIDAAKGVEDRTRKLMEVTRLRDTPILTFMNKLDRDIRDPMELLDEVEN
                     ELKIGCAPITWPIGCGKLFKGVYHLYKDETYLYQSGKGHTIQEVRIVKGLNNPDLDAA
                     VGEDLAQQLRDELELVKGASNEFDKELFLAGEITPVFFGTALGNFGVDHMLDGLVEWA
                     PAPMPRQTDTRTVEASEDKFTGFVFKIQANMDPKHRDRVAFMRVVSGKYEKGMKLRQV
                     RTAKDVVISDALTFMAGDRSHVEEAYPGDILGLHNHGTIQIGDTFTQGEMMKFTGIPN
                     FAPELFRRIRLKDPLKQKQLLKGLVQLSEEGAVQVFRPISNNDLIVGAVGVLQFDVVV
                     SRLKSEYNVEAVYESVNVATARWVECADAKKFEEFKRKNESQLALDGGDNLAYIATSM
                     VNLRLAQERYPDVQFHQTREH"
     gene            complement(37977..38654)
                     /gene="yjjG"
                     /locus_tag="IRB70_002075"
     CDS             complement(37977..38654)
                     /gene="yjjG"
                     /locus_tag="IRB70_002075"
                     /EC_number="3.1.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine 5'-nucleotidase"
                     /protein_id="HBC0631989.1"
                     /translation="MKWDWIFFDADETLFTFDSFTGLQRMFLDYSVTFTAEDFQDYQA
                     VNKPLWVDYQNGAITSLQLQHGRFESWAERLNVEPGKLNEAFINAMAEICTPLPGAVS
                     LLNAIRGNAKIGIITNGFSALQQVRLERTGLRDYFDLLVISEEVGVAKPNKKIFDYAL
                     EQAGNPDRSRVLMVGDTAESDILGGINAGLATCWLNAHNREQPEGIAPTWTVSSLHEL
                     EQLLCKH"
     gene            complement(38669..39115)
                     /gene="rimI"
                     /locus_tag="IRB70_002076"
     CDS             complement(38669..39115)
                     /gene="rimI"
                     /locus_tag="IRB70_002076"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBC0631990.1"
                     /translation="MNTISSLETTDLPAAFHIEQRAHAFPWSEKTFASNQGERYLNFQ
                     LTQNGKMAAFAITQVVLDEATLFNIAVDPDYQRQGLGRALLEHLIDELEKRGVATLWL
                     EVRASNAAAIALYESLGFNEATIRRNYYPTTDGREDAIIMALPISM"
     gene            complement(39084..39497)
                     /gene="holD"
                     /locus_tag="IRB70_002077"
     CDS             complement(39084..39497)
                     /gene="holD"
                     /locus_tag="IRB70_002077"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit psi"
                     /protein_id="HBC0631991.1"
                     /translation="MTSRRDWQLQQLGITQWSLRRPGALQGEIAIAIPAHVRLVMVAN
                     DLPALTDPLVSDVLRALTVSPDQVLQLTPEKIAMLPQGSRCNSWRLGTDEPLSLEGAQ
                     VASPALTELRANPTARAALWQQICTYEHDFFPRND"
     gene            39600..40631
                     /gene="rsmC"
                     /locus_tag="IRB70_002078"
     CDS             39600..40631
                     /gene="rsmC"
                     /locus_tag="IRB70_002078"
                     /EC_number="2.1.1.172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1207)-N(2))-methyltransferase
                     RsmC"
                     /protein_id="HBC0631992.1"
                     /translation="MSAFTPASEVLLRHSDDFEQSRILFAGDLQDDLPARLDTAASRA
                     HTQQFHHWQVLSRQMGDNARFSLVATADDVADCDTLIYYWPKNKPEAQFQLMNLLSLL
                     PVGTDIFVVGENRSGVRSAEQMLADYAPLNKVDSARRCGLYFGRLEKQPVFDADKFWG
                     EYSVDGLTVKTLPGVFSRDGLDVGSQLLLSTLTPHTKGKVLDVGSGAGVLSVAFARHS
                     PKIRLTLCDVSAPAVEASRATLAANGVEGEVFASNVFSEVKGRFDMIISNPPFHDGMQ
                     TSLDAAQTLIRGAVRHLNSGGELRIVANAFLPYPDVLDETFGFHEVIAQTGRFKVYRA
                     IMTRQAKKG"
BASE COUNT         9622 a        11302 c        10376 g         9638 t
ORIGIN      
        1 tgaatgccgg attgttaccc ggcatttgtc atttagcggt gatgtttgcc tggaccatga
       61 ccgccgtgat gatcatgagg agctttctta tggtggcgcg gcggtggcgg cggtccgtgt
      121 gggtgccagc gattgcctcg ccattcataa tgttgtttcc accagccgtg gtcgcgccag
      181 tgacctccat cccagtaata accgcgatta tcacgatcgc ctatctgtaa ttttactgac
      241 gggactaacg taatttccgc agcctgcgct gccatgggag cgaccagaac cagggaaagt
      301 gcgagtacga tagattgcat ctttttcaca ggttactcct tttatcattg cccgttatgg
      361 gtcgatatcc ggagattacg cgatgagaac ggcggttgtt attctccgca atcctaatct
      421 ctaagttacc gcatttattg agaatttctc ctttttccct gtcgtttttc tccataattt
      481 cttcataaaa aagccgggct gcataaaagc aaacccggcc tgattgagat aatgaataga
      541 tattactgat gattcatcat caatttacgc aacgcagcaa aatcggcggg cagattatgc
      601 gaaagcaagg gtaaatcggc acgttctgcc agctctttag gcagatccaa cgtttcaccg
      661 agaatcgctt ccacgctctc tttaaatttc gccggatgcg cggtgccgag gaacaaacca
      721 tattcgcctg gattcaactg gtcacgcagc gcacgataag ctacggcggc gtgcggctcc
      781 gaggtgtagc ccagttcttt taactcacgc attgtctgtt gcgtggtttc atcatccacg
      841 gctgcataac ccagctcttt cagttgccag attttgcggc ggaacaactc ttccacacgc
      901 ggccagttgt tcggctggct cacgtccatc gcgttggata acgtcgcctg agtcgctttg
      961 ggtgaccact gaccgtcgtg caggaaacgt ggcacggtat cgttcacgtt ggtcgcagca
     1021 ataaaacgtt tcaccggcag accgagtgac ttcgccagca gacccgccgt caaatcgccg
     1081 aagtttccgc ttggcaccga gacaaccagc tggttgcgcg cttcctgcgg cagctgcgca
     1141 actgcttcaa agtagtagca aatctgcgcc agcaaacggc tgatgttaat cgagttagct
     1201 gagtttaacc ccagcgccac tttcagctct tcatcatcaa acgcctgctt caccagcgcc
     1261 tgacaggcat cgaaatcgcc gtcgatggca acagtttcga tattgccgcc caatgtacag
     1321 aacagttttt cttgcagtgg actgattttg cctcgtggat agaggataac cactttcaca
     1381 ttcggtaaac cgtagaaagc atgagccact gccgctccgg tatcaccgga ggtcgcggtc
     1441 agaatggtca ctggcttatc gcccgcaata tgggtcagca tttgtgccat aaagcgaccg
     1501 ccgaaatctt taaatgccag cgttggcccg tggaacaatt ccagacaacc gacatcgctt
     1561 tcaacattgg cgaccggagc cgggaaggca aacgccgcgc gcacgcgctc ttccaggatt
     1621 tcctgcggga tttcatcacc aataaacgcc gagaggatct tcgcactgcg ggtgacaaaa
     1681 tccagcttca gcatctcatc aatttcagtc aggctgaatt ccggcaggtc gtgcggaaaa
     1741 aacagcccct gatttttgcc caacccctgg gttacggctt gcgcaaagct gacctgctca
     1801 ttgtgatctt tcagattgta gagtttcatt tagttttcca gtactcgtgc gcccgccgta
     1861 tccagccggc aaatatgaac aaaaccttcc tgattttgca ggtagttctt acccaaccag
     1921 tcggcaacgc gctgggcggt atccggcttg tcacacagag cgaacaaggt cgggccggag
     1981 ccggagatac cgctcgctac cgcgccgatt tccgcgaccg cctgccgcgc ctgccggaag
     2041 ccaggcagta accgttcacg gtagggttct gcgataacat ctttcatcag cttcgcggca
     2101 agctcaggct gacgggaata gcaggcgtga atgaagcctg ccagatgtcg cccgtgcgca
     2161 atgcaatcct ggcggcgata ctgcgccggt aaaatagccc gggcttctgc cgtcgagact
     2221 ttaatccccg gatacgccag cacccacagc cactcatcaa accctggcac ttgctggctg
     2281 atgatgtcgt tttcttcgat catcaactgc attccaccaa gaaaacacgg tgccacgttg
     2341 tcgtaatgaa tgctgccgga gatacgtcct tccagctcgc ccatcaaagc cagcaaacgg
     2401 gtgtcattaa gtggcttgcc gcagtgttca ttcatcgcca tcagcgccgc gaccaccgaa
     2461 caggcgctgg agcctaagcc cgagccgatc ggcatattct tttccagagt catcgccact
     2521 ggaatttgct tcccaagctc ctggcaaaaa cgctcccagc actgataaac gatattttcc
     2581 cgtggttctg acggcagctt atcggcaaag cgtccgaggt tgttgagacc gaatgtctct
     2641 gccgcctcaa ccgtgactac atctccgagc aatgcaccat caacgggtgt caccgccgcc
     2701 ccgagcacat caaacccgac gctcatattg gcactggaag ccggggcata aactttaacc
     2761 atgtcagact cctaacttcc atgagagggt acgtagcaga tcggcaaaga caccggcagc
     2821 ggtaacgtca ttgcccgcac catatccgcg cagcaccaac ggcagcggct gataatagtg
     2881 gctatagaag gccagggcgt tttcgccatt tttcactttg aacagcggat cattaccatc
     2941 cacttcggca atcttcacgc ggcagacgcc atcttcatca atattgccaa catagcgcaa
     3001 aacttttcct tcatcacggg ccttagccac gcgcgcggca aagagatcgt cgagctgtga
     3061 cagattcgcc ataaaagcgg caacatcacc ctcggcgtta aactctgcgg gcagcactgg
     3121 ttcaatttca atatccgcca gctccagttc acgtcccgtt tcacgagcga gaatcaatag
     3181 cttacgcgct acatccatac cagaaagatc atctcgcgga tccggttcgg tataacccat
     3241 ttcccgcgcc agagtagtcg cctcggagaa actcatgcct tcgtctaact tgccgaagat
     3301 ataagaaagc gaacctgaaa gaatgccgga gaacttcatc aattcatcac cagcattgag
     3361 cagattttgc aggttctcaa taaccggtaa tccagcccca acgttggtgt catagaggaa
     3421 tttacgccgc gatttttccg ccgcatgacg caacagatgg tagtaatcca tcgacgaggt
     3481 gttggccttt ttgttcggcg tgacaacgtg gaaaccttcg cgcaagaagt cggcatattg
     3541 atccgccact gcctggctgg aggtgcagtc aacaatgacc gggttcagca gatgatattc
     3601 tttcacgagg cgaattaagc gcccgagatt aaacggctct ttggcttgtg caagttcttc
     3661 ctgccagttt tccagattaa ggccatgcac actagtgagc agagccttcg agttggcaac
     3721 gccgcagaca cgtaagtcga tatgtttatt cttcagccag ctttgctgac gcttcagttg
     3781 ctccagcagc gcaccgccaa cgccaccgac gccaatcaca aacacttcga taacctgatc
     3841 ggtattgaac agcatctgat gagtaacgcg cacgccagtg gtcgcatcat cgttatttac
     3901 cacgacagag attgagcgtt cagaagatcc ctgagcaatg gcgacaatgt tgatattggc
     3961 gcgggccagc gcggcaaaga atttcgccga gatcccacgc aaggtgcgca taccatcacc
     4021 taccaccgag ataatggcca gccgttccgt caccgccagc ggctccagta agccttcttt
     4081 cagttccagg tagaactctt cctgcattgc ccgttcagct cgcacacagt cgctttgtgg
     4141 aacgcagaaa ctgatactgt attcggaaga tgattgcgta atcagcacca cggaaatacg
     4201 ggcgcgtgac attgcagcaa agacgcgcgc cgccatgccg accattcctt tcatccccgg
     4261 accagaaacg ctgaacattg ccatattatt cagattggaa atgcctttga ccggtaattc
     4321 gtcttcatca cggctggcac caatgagcgt acctggtgct tgaggatttc cggtattttt
     4381 aatcaggcaa gggatctgga actgggcgat gggggtaatg gtgcgggggt gaagaacttt
     4441 agcgccgaag taggaaagct ccatcgcttc ctggtaggac atcgacttta acaacctcgc
     4501 atcgggcacc tgacgcgggt cgcaggtata gaccccgtca acgtccgtcc aaatctcgca
     4561 acaatcggcg cgtaaacagg cagccagcac cgccgcggag tagtcggaac cgttgcgtcc
     4621 aagtaccacc agttcgcctt tttcattacc ggcggtgaag cctgccatca gcaccatgtg
     4681 atcagccgga atacgacttg ccgcaatacg gcgggtggac tcagcaatat cgacggtaga
     4741 ttcgaggtaa tgccccactg ccagtagttt ttcgaccgga tcgataacgg taacgttgtg
     4801 accacgcgct tctaacacgc cggccataat ggcgatcgac attttctcgc cacggcaaat
     4861 cagcgcagcg ttgatgctat ccgggcactg ccccaacaaa ctaatgccat gcaggacatg
     4921 ttttatttgg gcaaattcct ggtcgacgaa agttttcaat tgcgccagcg ggaatcccgg
     4981 ctgggcggcg gcgagtcccg tcaaaagttc ggcaaaaata cgttcggcat cgctgatatt
     5041 gggtaaagca tcctggccgc taatggtttt ttcaatcatc gccaccaggt ggttggtgat
     5101 tttggcgggg gcagagagga cggtggccac ctgcccctgc ctggcattgc tttccagaat
     5161 atcggcaacc cgcagaaaac gttctgcatt tgccactgat gtaccgccga acttcaacac
     5221 tcgcatggtt gttacctcgt tacctttggt cgaaaaaaaa gcccgcactg tcaggtgcgg
     5281 gcttttttct gtgtttcctg tacgcgtcag cccgcaccgt tacctgtggt aatggtgatg
     5341 gtggtggtaa tggtggtgct aatgcgtttc atggatgttg tgtactctgt aatttttatc
     5401 tgtctgtgcg ctatgcctat attggttaaa gtatttagtg acctaagtca ataaaatttt
     5461 aatttactca cggcaggtaa ccagttcaga agctgctatc agacactctt tttttaatcc
     5521 acacagagac atattgcccg ttgcagtcag aatgaaaagc tgaaaaatac ttactaaggc
     5581 gttttttatt tggtgatatt tttttcaata tcatgcagca aacggtgcaa cattgccgtg
     5641 tctcgttgct ctaaaagccc caggcgttgc tgtaaccagt cgaccagttt tatgtcatct
     5701 gccactgcca gagtcgtcag caatgccatg actcgttcgc gtaaagcttg cagttgatgt
     5761 tggtctgccg ttgtgtcact tttcgccggt tgttgtatta atgttgctaa ttgatagcaa
     5821 tagaccatca ccgcctgccc cagattgagc gaaggataat ccgccaccat cggcacacca
     5881 gtaagaacgt cagccaacgc taactcttcg ttagtcagcc cggaatcttc gcgaccaaac
     5941 accagcgcgg catggctcat ccatgaagat ttttcctcta acagcggcac cagttctact
     6001 ggcgtggcat agtaatgata tttcgcccga ctgcgcgcag tggtggcgac agtgaaatcg
     6061 acatcgtgta acgattcagc cagtgtcggg aaaactttaa tattatcaat aacatcacca
     6121 gatccatgtg cgacccagcg ggtggctggc tccaggtgtg cctgactatc gacaatccgc
     6181 agttcgctaa aacccatcgt tttcattgcc cgcgccgctg ccccaatatt ttctgctctg
     6241 gcgggtgcga ccagaataat cgttatacgc atattgccac tcttcttgac caaataaccg
     6301 cgaacagggt gatcactgtc aacttattac gcggtgagaa tttacaaatt attaacgtaa
     6361 gtcgcagaaa aagcccttta cttagcttaa aaaaggctaa actatttcct gactgtacta
     6421 acggtttaat tgttaaaaaa tgctacatat ccttctgttt acttaggata attttataaa
     6481 aaataaatct cgacaattgg attcaccacg tttattagtt gtatgatgca actagttgga
     6541 ttattaaaat aatgtgacga aagctagcat ttagatacga tgatttcatc aaactgttaa
     6601 cgtgctacaa ttgaacttga tatatgtcaa cgaagcgtag ttttattggg tgtccggccc
     6661 ctcttagcct gttatgttgc tgttaaaatg gttaggatga cagccgtttt tgacactgtc
     6721 gggtcctgag ggaaagtacc cacgaccaag ctaatgatgt tgttgacgtt gatggaaagt
     6781 gcatcaagaa cgcaattacg tactttagtc atgttacgcc gatcatgtta atttgcagca
     6841 tgcatcaggc aggtcaggga cttttgtact tcctgtttcg atttagttgg caatttaggt
     6901 agcaaacatg cagaccccgc acattcttat cgttgaagac gagttggtaa cacgcaacac
     6961 gttgaaaagt attttcgaag cggaaggcta tgatgttttc gaagcgacag atggcgcgga
     7021 aatgcatcag atcctctctg aatatgacat caacctggtg atcatggata tcaatctgcc
     7081 gggtaagaac ggtcttctgt tagcgcgtga actgcgcgag caggcgaatg ttgcgttgat
     7141 gttcctgact ggccgtgaca acgaagtcga taaaattctc ggcctcgaaa tcggtgcaga
     7201 tgactacatc accaaaccgt tcaacccgcg tgaactgacg attcgtgcac gcaacctgct
     7261 gtcccgtacc atgaatctgg gtactgtcag cgaagaacgt cgtagcgttg aaagctacaa
     7321 gttcaatggt tgggaactgg acatcaacag ccgttcgttg atcggccctg atggcgagca
     7381 gtacaagctg ccgcgcagcg agttccgcgc catgcttcac ttctgtgaaa acccaggcaa
     7441 aattcagtct cgtgctgaac tgctgaagaa aatgaccggc cgtgagctga aaccgcacga
     7501 ccgtactgta gacgtgacga tccgccgtat tcgtaaacat ttcgaatcta cgccggatac
     7561 gccggaaatc atcgccacca ttcacggtga aggttatcgc ttctgcggtg atctggaaga
     7621 ttaatcggct ttaccaccgt caaaaaaacg gcgcttttta gcgccgtttt tatttttcaa
     7681 ccttatttcc agatacgtaa ttcatcgtcc gttgtaactt ctttactggc tttcattttc
     7741 ggcagtgaaa acgcatacca gtcgatatta cgagtcacaa acatcatgcc ggccagcgcc
     7801 accaccagca cactggttcc caacaacagc gcgctatcgg cagagttgag cagtccccac
     7861 atcacaccat ccagcaacaa cagcgcgagg gtaaacaaca tgctgttgcg ccagcctttc
     7921 aataccgcct gcaaataaat accgttcatt aacgccccaa tcagactggc gattatccat
     7981 gccacggtaa aaccggtatg ttcagaaagc gccagcaaga gcaaataaaa catcaccaat
     8041 gaaagcccca ccagcaaata ttgcattggg tgtaagcgtt gcgcggtgag cgtttcaaaa
     8101 acaaagaacg ccataaaagt cagcgcaatc agcagaatgg catacttagt cgcccggtca
     8161 gttaattggt attgatcggc tggcgtcgtc actgcgacgc taaacgcggg gaagttttcc
     8221 cagccggtat cattgcctga agcaaaacgc tcaccgagat tatttgcaaa ccagctgctt
     8281 tgccattgcg cctgaaaacc tgactcgcta acttcccgtt tggctggcaa aaaatcacct
     8341 aaaaaactgg gatgcggcca gttgctggtt aaggtcattt cgctattacg cccggcaggc
     8401 accacagaaa gatcgccggt accgcttaaa ttcagtgcca tattcagctg caggttctgc
     8461 ttgcgccagt ccccttcggg taaagggata tgcacgccct gcccgccttg ctctaacccg
     8521 gtaccgggtt caatggtcag cgctgttccg ttaacttcag gcgctttcac cacaccaata
     8581 ccacgcgcat ccccgacgct aatcacaata aagggcttgc ctaagatgat atttggcgcg
     8641 ttgagctcgc taagacgcga aacatcgaaa tcggctttta gcgttaaatc actgtgccag
     8701 acctgaccgg tataaatccc tatcttgcgt tcttccacgt tctgattgcc atcaaccatc
     8761 aatgactcag gtaaccaaaa atggataaaa cttcgtttcc gctccacggt tttatcctct
     8821 tcctgcaccg tataaagctc ggtcacagga atagcgataa gcggcccaac gagtttttgc
     8881 ggcccgctgg tactttggcg aatcgcatct tccacatcgc tacggtaatc ggcacgttcg
     8941 acaatcactt gccgaatcag cattatcgga atcaacaaca gcaatactgc accaaacaag
     9001 gtggtcattt tccagaacag gggggatttc aacatagtct tctcctttgc aatggcagca
     9061 ggatacgaag gctatgtggg aagaatttga agctatgtga agtgacggtg aagtcgtagc
     9121 gaggccagca cgccacctgc ctgcacgttg cgcagcgtga cttcgccgtt aaacaaacgg
     9181 gcgacctcac tgacgaacgc caaccccaga ccgctgcttt tttgcccatt tgcacgcggc
     9241 aaagagtaaa agcgttcaaa aatgcgtgac agcgcgtagt caggaatacc actaccggta
     9301 tccagcacct taagcgtgac gtgttcctga tccacttcgg cgcttagcgt tatacgaccg
     9361 ctctcggggg taaaatcgat ggcgttatcc agtaaattcc ccagcgcctg atccagtaac
     9421 gccggttcag cagcaacatt aacctcggtg ggcgtaacat gtagagtgat gtttttttct
     9481 gccaactgca cggtgcgcgc ttcgctgacg cggcggaata atgccgccac atcaacagca
     9541 gtcaaaacga cttcctgacg attctccagt cttgcctggc gtagtaacgt ttccaccagt
     9601 gcctgcattc gcgcattttg cgtcagaatg ttgtcggtaa aacgagccac cacttccggc
     9661 ggcggacctt cgcgtaaaat ttccgccgcg ccacgaatcg ccgccagtgg gctttttagc
     9721 tcatgggtta acgcataaac atactgctca atatagtttt tcccttccag cttcacgcgc
     9781 atactttcca gcgcctgcgc gagtttacgc agttcgctac taccgagatc gggaagagga
     9841 acgggcttat tgtcagtgac ggaatcagca tagcgagtga gccgggcaat ggagcggttg
     9901 atccaccaaa ccatgcctgc gccaatcacc agtgcgatcc ccaacaaaat ggcgctggcc
     9961 cataaaattc gccgctcgct gcgtttaatg accggagcca tcgccgcgtt cggtttgcct
    10021 acgctcaaaa cgccaataag ccgcgagccg tccataatcg gcgcggcaac atacatcacc
    10081 gaactttcgg gatcggcagg attttgcaac gtgctacgcg caccatactg accacgcaac
    10141 gttagccaga cgtcattcca gcgcgaataa tcctgtccaa cggctttatt tgccgaatcg
    10201 aacaatactt tgccctgcgc atcggtcata tagacatgat attcattgcg cactttgtta
    10261 atgccaccaa tattggcgcg aaacgggcga tgttgtagct gattaaacgc ctgcgccagt
    10321 tgcccatgcg ttgggtcccc agagagcaaa tcgggacgcg ccagctccgc cagtaacgtt
    10381 gccgtgtcga tcaacgtccc ctccgttgct cttcgcacgc ccggtttaac ttctttgaca
    10441 aaaatagcca gtacgaacca ggccgccacc gccaccagta aaaaatagcc cagcagcaac
    10501 cgcatgccga tacgcattac aagcccctca ggctatatcc catgccgcga tgagtattaa
    10561 tcggtgaaag atcggggttg atggcgcgca gcttggcacg cagcgtttta atgtgggtat
    10621 cgacggtgcg atcgtaggtg tcctgcgcat cttcccacac gctatccatt agttgctggc
    10681 gggaccagac gcggcctggc gacttgagta acgtcttcag caataaaaac tcataccgcg
    10741 tcagcgttaa tggcgtgtca aaccagctga tctgcgccgc gggttcattc aattcaaaat
    10801 gaccaatacg gatgacggga gacggcgtcg agaacttctt cacccgacgc agtaaggtgc
    10861 gcaccctggc gcacacttcg cggggtgaaa acggtttagc cacatagtcg tcagcgccaa
    10921 tttccagccc aagcaggcga tcgacctctt cacttcgggc cgtcaggaac agtacaggta
    10981 acgccggatg gagcgccagt aactggcggc acaattcaaa gccactgata tcaggcaaac
    11041 caacgtcgag aatcatgacg tcgggaacct gctggcgagc tttatccagc accggcaaac
    11101 ctcgctcaaa gacctcgacg gcaaaacctt cctgctgcaa catgtagacc agcgtgtcgg
    11161 ctatcccttg ctcatcttcc actaaccaga ccgtttcccg ttgcataaat cgcctctgtt
    11221 attgccgcca cggcatgaca ggaaccgcgc taatcgcgtt tttcggcgaa ccttctacaa
    11281 ctttgtcgga gtaagccaga taagcgagcg cgttgcgttt ggcgtcataa aagcgcacga
    11341 cctgtaacga cttaaagacc agggacgtgc gttttttgaa tactacctcg ccctgagctt
    11401 tgccgttttt aatacgatcc gacagttcaa tcggcccgac ttgctgacaa gaaatggccg
    11461 catcggaggt atcttctgcc aggcccaatc cccctttaat accaccggtt ttcgcccggc
    11521 tcacataaca ggtgacattt ttcacatcgg gatcgtcaaa ggcttccaca acaattttgt
    11581 gatccgggcc gatcatttta aatacggtgt cgaccgaacc aatctcttct gcatgagcca
    11641 atggccccag cattatcagg cttaaagaca ggatcaaatg cttgtatttc atattgttac
    11701 catttttatc tattacacga gcaattagtt cgtcacggta aataacatat tgattaagaa
    11761 caaaatctca attcttttat ttccgtcaag ccctaaaaca tactctacta agaaaaaaac
    11821 actgaatgct aaaacagcaa aaaatgctat tatccaatta cctgatgtca ggtgctcgtt
    11881 gttgaaagga tgaggatatt ttatggatca ggccggcatt attcgcgacc ttttaatctg
    11941 gctggaaggt catctggatc agcccctgtc gctcgacaat gtagcggcga aagcaggtta
    12001 ttccaagtgg cacttacaga gaatgtttaa agatgtcact ggccatgcta ttggcgcgta
    12061 tattcgtgct cgtcgtttgt cgaaatcggc ggtcgcacta cgcctgactg cgcgtccgat
    12121 tctggacatc gcgctgcaat accgcttcga ctctcaacag acatttaccc gcgcattcaa
    12181 gaagcagttt gcccagactc ctgcacttta ccgccgttct cctgaatgga gcgcctttgg
    12241 tattcgcccg ccgctacgtc tgggtgaatt cacaatgcca gagcacaaat ttgtcaccct
    12301 ggaagatacg ccgctgattg gtgttaccca gagctactcc tgttcgctgg agcaaatctc
    12361 tgatttccgc catgaaatgc gttatcagtt ctggcacgat tttctcggca acgcgccgac
    12421 cattccgccg gtgctctacg gcctgaatga aacgcgtccg agtcaggata aagacgacga
    12481 acaagaggta ttctatacca ccgcgttagc ccaggatcag gcagatggct atgtactgac
    12541 ggggcatccg gtgatgctgc agggcggcga atatgtgatg tttacctatg aaggtctggg
    12601 aaccggcgtg caggagttta tcctgacggt atacggaacg tgcatgccaa tgctcaatct
    12661 gacgcgccgt aaaggtcagg atattgagcg atactacccg gcagaagacg ccaaagcggg
    12721 agatcgccca attaatctgc gctgtgaact gctgattcct atccgccgtt aacgctgcag
    12781 ctcatctaat gcaggggcgt ccagatgcga gatgtcccct gcggtttcaa cgacccagcc
    12841 agacgccagc cacaggcttt cctgataatc cacgcgcgaa atagaacagt tacgtagacg
    12901 taagcggcgc tctgcccatg ctggtaatcc gagaatcgta ctcaccagac atcccagtgc
    12961 aataccatgg ctcaccagca gcggtcggct tccctgcggt aagtcccggc aagattccag
    13021 tgccgcattg acgcgatcgc tgagctcctg cattgactcg ccttcaggaa tacgcccgtc
    13081 aacggtgcca ttgaccagct gccgacgcca gttctcttct tcttcggtca gagaatcgat
    13141 atgtcttttt tccagcacac ccatgtttaa ttcacgcagg cgagaatcaa agatgatgtc
    13201 acagccgcag gcctgggcga tgatttccgc cgtacgccgg gtgcgtccta aatcgctact
    13261 gataatatgc gtaatgccaa gctctttggc acgggttgcc acctgcatcg cctgttgctc
    13321 acctttggcg gtcagcgggc tgtcagactg gccctgaata cgtcgctcgg cgttccactg
    13381 cgtttcaccg tggcggacta ggtatacctg taacatgctt tttttccgta tactgctgta
    13441 acgttaattt tctgagtaat gctgattatg caccaagttg tctgtgcgac caccaatccc
    13501 gctaaaattc aggccattct gcaggcattt cacgagatct tcggcgaagg atcctgccat
    13561 attgcatccg ttgccgtcga gagcggtgta ccggaacaac cctttggcag tgaggaaacg
    13621 cgcgctggcg cacgaaatcg ggtagcaaat gcccgccgtt tacttccaga ggctgatttt
    13681 tgggtggcga ttgaagctgg cattgatggc gacagcactt tcagttgggt ggtgattgaa
    13741 aacgccagcc agcgcggcga ggcgcgttcg gcaactttgc cgttacctgc ggtgattctg
    13801 gaaaaagtgc gtgaaggcga ggcgcttggt cccgtgatgt cgcgttatac cggtattgat
    13861 gagattggtc gtaaggaagg ggcgatcggc gtgtttaccg ccgggaaact cactcgcgcc
    13921 agcgtctatc accaggcggt gatcctggcg ctgagtccgt ttcacaatgc cgtgtatcag
    13981 gcattgtagg acggataagg cgttcacgcc gcatccggca ttcggtgcac gatgcctgat
    14041 gcgacgctgc cgcgtcttat caggcctaca aaatcaatcg cttttcagca acacctcttc
    14101 cagccactgg cgcagctcca cgggcgcggc tttcaggctg ttagatccac gcgtaatcgt
    14161 cgcgatgccc gcgccgagtt cattttttaa ctcacgctga ctcatttcgc cacgcaacag
    14221 ctcttcgaca atacgcacgc gagtccccaa cgcttcgcgc tcatctggcg tcagcatcag
    14281 gtttaacaac ggtaaatgga gatcgttttg gtaggcattc ttaagcaggt cgacaaaacg
    14341 taaccactcc tggtgacgct gttctgccat cgctgctgaa tagggtgatt gttgggccat
    14401 aatatgtcgc cattgttagc gggggaagca aaatgcctcc cccggttgta ctcgctaaag
    14461 agtacgatag catatcataa acgtgcggat cagtaacgac gtccccattc cgtggcgctc
    14521 atcaacgtcg gtttatcccc catgaaatag cggtagtaag cgtcataagc cagcacgttc
    14581 ttcacataac cgcgcgtctc ggagaacgga atactctcga caaatgccac agcgtcgata
    14641 cgcccggcgc tgttgccaag ccaggttcgc acccgtccag gtccggcgtt ataagctgct
    14701 gaggagaaaa tacggttatt gccaaactgc tgataaacat attgcaggta actggtgcca
    14761 atgttgatgt tcgtttccgg atccagcaat tgcccagggc tgctataact aggaatagag
    14821 aacatcttca ccgtatgggt cgctgtacca ggcataatct gcatcaggcc gctggcccct
    14881 accggtgatt tcactttcgg attccaggcg ctctcctgac gggcaatcgc catcgcatag
    14941 ctttgcggga tctctttccc actggtgtaa cgtttgaaaa gatcgttgta agccagcggg
    15001 aatcgctctt ccagatgatc ccaaagcttc ccggcgatcg ttgcctgaac gctaagatcc
    15061 caccattggt tattgaaagc ataccgagcc agttgagcct gctctgtttt tgacttgctc
    15121 ttcaccagat tggcccactc gctacgcgcg gtgttatcga gattccagta catcaactcg
    15181 cgcacgcgcg ccatctccgg cccctgagtc agggcgctgt caacattctg cggcgcttta
    15241 tcaatcttca gctcatactc ttctccgatg cgttgtgctg caaccatcgg gtagaaacca
    15301 cgctgttgca tgagttgatg caaaatctct tttgcttcag cttcacgtcc gcgttccagc
    15361 aataaatccg cctgccagta acgccattca tctttctctt ttgcttccat cggcagacgc
    15421 gccagccagg tattcaggcc gcgacgatcg ccggtgccaa gtgccattcg cacacggcgt
    15481 tcaatcaacg acgtggattg cgagcgcata atggcgtcat cgcgccattt cgcctgctcg
    15541 tcggtgacat cgttgcccat caaacgccag gcgacgatat cgcgcagctc ctgaatctga
    15601 tcttcattaa gctgctgcgc ctgggcaagc gacgggatca tcagccgtgc attttcagca
    15661 tcctgccgcg ccacactggc aaacgccacc gctgccattt gacgggtaaa atcggtcgct
    15721 ccggttgtac gcgcgaaggt cagtaccgta ttagggttgt tcgccagtga aatgattgcc
    15781 gaggcgatag tctggtaatc ggcaggcatc tgccctgcca gcactgttac caggccagtg
    15841 ttacccgctt tcatcgccag acggatacgc tctaaatacg ccagcggatc ttgtttacct
    15901 gacgcacgcc agacgctaaa taacttgtca caggcgttag gctggctctt gccggttagc
    15961 cacagctctt tcgccccttg ccaggcttct tcactctgcc cggtgttcca tttcgcatag
    16021 tagtaattac attgcgcttc ggtagttccg ggcttttccg ggctaaaggc taacaagcca
    16081 cgccagtctt cacgccgcgc cagttcattg acgaaacgag attgcagcgt gcgagcggga
    16141 ggaagcgtgg ggttagcgcg aacaaagtta gtgaccgtca ccgccggttg attcatcaga
    16201 tcatcggtga tctggcggta ttccaggtag ggataaagcg gataatcctt cagtctaggc
    16261 atcatttgtt cgaccacatc catctgtcga ttatcccagg cctgcttgat ttgcgcgtaa
    16321 cggctacgct gctcatccag tgagtcggct cgcgccacgc tgctgaccgt cagcagacag
    16381 acaccggcag ccaacagccg ccaggtaact tgtttggctt tttccacaag cgcatcctct
    16441 aagtgtaaat acatcaatgc agcgtcatgc cgcgtaatag atttatgcta accagtcatt
    16501 gccgtttacg ccacgttacg gacacttttt tacttttact gcgaaggtga tcgaccaact
    16561 gggattaggc ggggaaaaag gctacacttc gcctttgaaa actcatcatc acgataaaca
    16621 tagaggcgaa gtccaacgtg gctcaattcg tttataccat gcatcgtgtc ggcaaagttg
    16681 ttccgccgaa acgtcatatt ttgaaaaaca tctctctgag tttcttccct ggggcaaaaa
    16741 ttggtgtcct gggtctgaac ggcgcgggta agtctaccct gctgcgcatt atggcgggca
    16801 ttgataaaga catcgaaggt gaagcacgtc cgcagccaga catcaagatt ggttatctgc
    16861 cgcaggaacc gcagctgaac ccggaacaca ccgtgcgtga gtccattgaa gaagcggttt
    16921 ctgaagtggt taacgccctg aaacgcctgg atgaagtgta tgcgctgtac gccgatccgg
    16981 atgccgattt tgacaagctg gccgctgaac aaggccgtct ggaagagatc attcaggctc
    17041 acgacggtca taacctgaac gtacagctgg agcgtgcggc ggatgcgctg cgtctgccag
    17101 attgggacgc gaaaatcgct aacctctccg gtggtgagcg tcgtcgcgtg gcgttgtgcc
    17161 gcctgctgct ggaaaaacca gacatgctgc tgctcgacga accgaccaac cacctggatg
    17221 ccgaatccgt ggcgtggctg gaacgcttcc tgcacgactt cgaaggcacc gtggtggcga
    17281 ttactcacga ccgttacttc ctcgataacg ttgcaggctg gatcctcgaa ctggaccgcg
    17341 gtgaaggtat tccgtgggaa ggtaactact cctcctggct ggagcagaaa gatcagcgtc
    17401 tggcgcagga agcttcacaa gaagcggcgc gtcgtaagtc gatcgagaaa gagctggagt
    17461 gggtacgtca gggtactaaa ggccgtcagt cgaaaggtaa agcacgtctg gcacgttttg
    17521 aagagctgaa cagcaccgaa tatcagaaac gtaacgaaac caacgaactg tttattccac
    17581 ctggaccgcg tctgggcgat aaagtgctgg aagtcagcaa cctgcgtaaa tcctacggcg
    17641 atcgcctgct gattgatgac ctgagcttct cgatcccgaa aggggcgatc gtcgggatca
    17701 tcggtccgaa cggcgcgggt aaatcgaccc tgttccgtat gatctccggt caggaacagc
    17761 cggacagcgg caccatcact ttgggtgaaa cggtgaaact ggcatcggtt gatcagttcc
    17821 gtgactcaat ggataacagc aaaaccgttt gggaagaagt ttccggcggg ctggatatta
    17881 tgaagatcgg caacaccgag atgccaagcc gcgcctacgt tggccgcttt aactttaaag
    17941 gggttgatca gggtaaacgt gttggcgaac tttccggtgg tgagcgcggt cgtctgcatc
    18001 tggcgaagct gctgcaggtt ggcggcaaca tgctgctgct cgacgaacca accaacgacc
    18061 tggatatcga aaccctgcgc gcgctggaaa acgccctgct ggagttcccg ggctgtgcga
    18121 tggttatctc gcacgaccgt tggttcctcg accgtatcgc cacgcacatc ctggactacc
    18181 aggatgaagg taaagttgag ttcttcgaag gtaactttac tgagtacgaa gagtacaaga
    18241 aacgcacgct gggcgcagac gcactggagc cgaagcgtat caagtacaag cgtattgcga
    18301 agtaatgcgt aaaatgccgg atgcggcgtg aacgccttat ccggcctaca aaccaagaaa
    18361 tttcaatacg ttgtgaatct ccaggcctga taagacgcgg taagcgtcgc atcaggcatt
    18421 gagcaccgaa tgccggatgc ggcgtgaaca ccttttccgg tctacaacag ccttagcatc
    18481 ctcaatttcg tggcgggtca cccgtgcagg ttttttcaaa ccttgtttaa tctcgacagc
    18541 ctcttccaga gaggttttca actcatcaaa aaaactcatt ttatacctcg cctttgagca
    18601 gtttcgtcac ggttatcctt gctcccccat catctcccgc accagctcca cgcagcgcag
    18661 gaaacggctg tcgtaatcgt cctcttcaac ccgcacgaat tcgatattgt tctcttccag
    18721 catctccacc agcaagttct ggaactcttt gcgatccacc gaactgccga ggctgcgtaa
    18781 accatccgcc acccacggcg tgttgttctc cagcaggatc accagatcga aacggtattc
    18841 atcaatcagc gcctgcacga acggatgctc acgcccttcg tactttttgc agaacgcctg
    18901 ggtagtgaca aaatcggtgt caataaacgc cactttattg gcgtatttca ctgcaaaatc
    18961 aatgtattgt gcgtggccca acgcgatttt atcgtagtcg gaatactgca atgcgatctc
    19021 atcaccgccg aggtgtgaaa agacataatc gcggccatat tcccacgcac tggtggtgtt
    19081 gaagatattg gcaagtttgt ttaccagggt ggatttaccg ctcgactcgc cgccaaggat
    19141 cgccacggta cgcacaaaaa acggcttcac ttcggtagga atatattccc agtagcggaa
    19201 cgggttttcg cggatctgcg caccgctgat actcataaag gtacgtttcg gatcgaccag
    19261 caccgtctcg atccccagat gttccatata ctgtggcgca tcggcttctt ccgaggtgta
    19321 gatcagatcc ggctggatcc ctttttcagc cataaacttt ttgataccgt tgctccacac
    19381 atcccagccg tgcggatacg gctccatgcc ctcttcgttg aaagcatgaa tgcgaatatt
    19441 tttctgatat ttaaaagttt gcaataacca gcgcagacga tccggcacgg tcggctgctg
    19501 cgacatggca ctgtcttcga acaacgcgcg gtcacgggta tcgtcaaaac ccataatgat
    19561 atgcagctcg tcaacctggc tacaggcgcg ctggataaga tagatatgtc cggtatgcag
    19621 cgggtagaac ttaccgaata ccacaccgat cgttttcttc tgtcggggaa attcaagccc
    19681 caaaaaacgg tgcaacgcct ccagcttttg cgcgctaggg cttttgattt tggcattcag
    19741 taactggctt aaataccctt tggtcatacc gctggcatca gctacctgct gtagcgtgca
    19801 gccctgttgc ttgatggcag ttttcaggta atcaaatgac gacatatctc cctccgtatc
    19861 tctcattata agtcgtcgaa cacgctaagc gcgtcggaga gttttttaac gccaaaaatc
    19921 tgcatccctt ccggcgcttt tttcggtacg ttagccgccg gaacaatcgc ccggcgaaaa
    19981 ccgtgtttcg ccgcttcaga gattcgttcc tgcccgctgg gcaccgggcg gatctcccct
    20041 gccagcccga cttcaccaaa caccaccaga tcctgtggca gcggtctgtc acgcaggctg
    20101 gaaaccatcg ccagcagtaa cgctaaatcg gcactggttt ctgtcacctt cacgccgccg
    20161 accacgttca caaacacatc ctgatcggcc atttgcagac caccgtgacg gtgcaagaca
    20221 gccagcagga tcgccagacg gttttgctcc agacctaccg ccacgcggcg cggattcgcc
    20281 atcatcgagt gatcgaccag cgcctgaatc tccaccagca acggacgcgt tccttcccac
    20341 accaccatca cggagctgcc ggaggtcact tcatctccgc gacttaagaa aattgccgaa
    20401 gggttgctga cttcacgcag cccctgttcg gtcatcgcga agacgcccag ctcattcacc
    20461 gcgccgaagc ggtttttatg gctgcgcaag gtgcgaaaac gggagtcggc atcaccatcc
    20521 agaagcaccg aacagtcgat acagtgttcc agcactttag ggccagccag cgagccatct
    20581 ttggttacgt gccccaccat gacaatcgcc acaccgcgcg ttttggcgaa gcgcgtcaga
    20641 taagccgctg tttcacgcac ctgcgccaca ctgccaggcg atgattgtat atccgccata
    20701 tgcatcacct gaatggagtc aattaccatc agcttcggtt gctcttcttc ggcaatcagg
    20761 cagatctgtt cgatgctggt ttccgacaac atattgagat tgtcagtcgg caggccaagg
    20821 cgatgagcgc gcattgccac ctgttgcagc gactcttcgc cggtgacata cagcgttttc
    20881 atctgctggg ccagtttgca cagcgtttgc agtagcagcg tggatttccc cgcaccaggg
    20941 ttaccgccaa tcagaatggc acttcctggc accacgccgc cgcctagtac gcggtcgaac
    21001 tctttaaatc cggtggaaaa acgcggcagc tcttcaaggc tgatatcgga gagtttctgg
    21061 acttttgcca ccccggcgct accggcatag ccgctgagac gctcgttacg cgccaccgtt
    21121 ggcgacgcag caagacgcac ctcggtgatg gtgttccagg catgacaggc actgcactgc
    21181 ccctgccagc gcggataatc ggccccgcat tcattacaaa caaaggcgcg ttttggagct
    21241 tttgccacgg tgtacctcgt taatgctgtg ccgcccgcag gatggcgggc gagcaattac
    21301 ttctgattca ggctgcctga gaggatgcag aataccccca tcaggtcagc gtgacggatg
    21361 gtgacttccg ccttttcatt cacttttggc ttggcatggt aggcaatccc cagccctgct
    21421 gctttgatca tcggcaggtc attagctcca tcgccaatcg ccacggtctg cgccagcggg
    21481 atttcatact cctgcgcgag gcgagtcaaa gttttcgctt tgtactgcgc gtctacgatg
    21541 tcgccgatca cattgccggt aaatttaccg tccatgatct ccagttcatt ggctaccacg
    21601 gcggtcaggc gcagcttgtc gcgcagatat tcagcaaaga aagtaaagcc gccggaggca
    21661 atcgccactt tccagcccag cgtttccagc ttgagcacca gttgcgttaa gcctggcatc
    21721 agcggcagat tttcacgcac ctgttgcaga atattggcgt cagcgccttt cagcgtcgcc
    21781 acacggctgc gcaggctggc ggtaaaatcg agttcgccgc gcatcgcccg ttcggttact
    21841 tccgccacca tctcgcccgt tccggccagt ttggcaattt catcaataca ttcaatctgg
    21901 atggcggtgg aatccatgtc catcaccagc aaacccggcg tgcgcaggtg tgggattttc
    21961 cccagcggcg cgacatccag ctgcgcttcg tgggccaggc gcgtagcccg ggcggtaagc
    22021 gaacctgcca gacgaatcac ctgataatct tccacgcacc aggcggcaac aatcaccatc
    22081 gccgcgccca gtttgctctg gtattgggtc agacgttgtt tatccagccc acgaccatac
    22141 agcagccagc cgctacgacc tgcgtggtaa tccagtggca tcacttcatc accacttaat
    22201 gaaagaggca gaccaggcca taaagagaca tcttcaggca ggtcgcacca ggtaatgtta
    22261 ggcattaagg ctcctgtaaa atcgttcgaa gcagggaaaa taacgcatga ggctaccttg
    22321 tatccattgc ttctggcaac attaagtctc aaattttcaa agggtggaag atggctcgca
    22381 caaaactgaa attccggctg catcgggcag tgattgtcct gttctgtctt gccttgttag
    22441 tggcgctgat gcagggggca tcatggttta gtcaaaacca ccagcgacag cgtaatccgc
    22501 agctggaaga actggcccgc accctggcgc ggcaggtgac gctgaacgtt gcgccgctga
    22561 tgcgtaccga ctcgccggat gaaaaacgta ttcaggcgat cctcgatcag ttaacggatg
    22621 aaagccgcat cctcgacgcg ggcgtgtatg acgaacaagg cgatcttatc gcccgttctg
    22681 gcgaaagcgt cgaagtgcgt gaccggctgg cgctcgacgg taaaaaagcg ggcggctatt
    22741 ttaaccagca gattgtcgaa cccattgcag ggaaaaatgg tccgcttggc tatctgcgcc
    22801 tgacgctcga cacccatacg ctcgccaccg aagctcaaca ggtggataac accactaaca
    22861 ttttacgcct gatgttgttg ctctcgctgg caatcggcgt agtgctgacc cgcacgctgc
    22921 tacaggataa acgcacccgc tggcagcaat cccccttcct gttaaccgcc agcaaaccgg
    22981 tgccggaaga ggaagaaagc gagaaaaaag agtgacccat tactacaaga aaggaaatcg
    23041 ttatgtccac attacgcctg ctcatctctg actcttacga tccgtggttt aacctggcgg
    23101 tggaggagtg tatttttcgc cagatgcccg ccacgcagcg cgttttgttt ctctggcgca
    23161 atgctgacac cgtggtgatt ggtcgcgcgc agaacccgtg gaaagagtgt aatacccggc
    23221 ggatggaaga agataacgtc cgcctggcgc ggcgcagtag cggtggcggc gcggtgttcc
    23281 acgatctcgg caatacctgt tttaccttca tggctggcaa gccggaatac gataaaacga
    23341 tctccacctc gattgtgctc aatgcactga acgcgctcgg tgtcagcgcc gaagcgtccg
    23401 gacgtaacga tttggtggtg aaaaccgccg aaggcgaccg taaagtctca ggctcggcct
    23461 atcgcgaaac caaagatcgt ggcttccacc acggcacctt gctactcaat gccgacctta
    23521 gccgcctggc aaactatctc aacccggata aaaagaaact ggcggcgaaa ggcattacgt
    23581 cggtacgttc ccgcgtgacc aatctgaccg aattgctgcc gggaattacc catgagcagg
    23641 tttgcgaggc catatccgaa acctttttcg cacattatgg cgagcgcaca gaagcggaaa
    23701 tcatctcacc ggacaaaacg ccagacttgc cgaactttgc cgaaaccttt gcccgccaga
    23761 gtagctggga atggaacttc ggtcaggctc cggcgttttc gcatctgctg gatgaacgct
    23821 ttacctgggg cggcgtagaa ctgcatttcg acgtcgaaaa aggccatatc acccgcaccc
    23881 aggtgtttac cgatagcctc aaccccgcac ctctggaagc tctcgccgga cgactgcaag
    23941 gctgcctata ccgcgctgac atgctgcaac aagagtgtga agcgctgttg gttgacttcc
    24001 ctgaacagga aaaagagcta cgggagttgt cggcgtggat agcgggagcg gtacggtagt
    24061 tacccgccca tgcgggcaac tttcccttcg atttgccgga ttttttccgg catttcctgc
    24121 gcaatgtggc gaaacgcctc gctgatacgc ggatctccag cgaccgtttg ccagaactgc
    24181 tgcgccagcg ggatcgccgt taaccatgcg cttttactga cgttaagatc aaacttcacc
    24241 tcaatggcag catcacgcag cattccggcg atgtttggtg cataggccat cggcagcatg
    24301 tcgtagacgg gcgtcagcgc aaatggtggt tcagataaat aaaatgataa attgcctgcg
    24361 tgcatatcgc tgttggcgat aagtcgccca aacgcccaga tcacttctgt ttgcgccacg
    24421 ctctggtgag tgacaaattg ttgctcacac aaacggcgca ttgcctccgg ccacgatccc
    24481 ggagaagaga taaactcact ctgcaccgcc tccagcgaca caatgggcaa gcgaccatcg
    24541 ttacctttac agtcaaagcg ttccgcttca aggaatacct gcctgttact tgttacaagc
    24601 accgttgact cgatggcgtg gatcccaccg tcgcacagga tttgcgcggc aatagattca
    24661 gcaattagca ggtcacccca acgttggctg accgcggttt gctgtggcac ggtgaatttc
    24721 accaacacat gtttattgcc tgacggcgtt tgtacatagc aggtaaattt tggctgctcg
    24781 ccgcccgcag aagaacccac aatttctcct gccagtgcat catgcgccag ttgttcgtaa
    24841 cgggtgagtt tttgatccag aggaattgcc gcagggcgtg gtgcagtaat ccatcgctga
    24901 taattcctct ccccgaccag ccagcccccg gtatattcac cgttaaatac ggtcagggcg
    24961 tagagcacat cttcttcctg ccagagacgt atatcttcag tcagattcag ttgtccggct
    25021 aaatttctgc cccacgcgcg ccccaaaaac ccctgtggtc ggagatcggt caaataccag
    25081 ggcaaaccat caaaccactg ttcgtcgccc tttccgcctg tgaccagaca acttccctgc
    25141 ggccagcaca actggatgtc ggcgaattta tgcgcctttc cggcatcgtc cacccgccag
    25201 acgggaatac gttcaattcc gcgataagga cgcagcagtg catatcgcgt tgcccgtgct
    25261 ttgccaaagc gaatcacccg atcttctctg gcaacaagac gtgagaacgt cgcctgactg
    25321 attgccagac gctggcgcaa ttccggggca gaacgcggcc cttgcagtaa aagatcggtc
    25381 agttcgctca ttaatgaata gattcgtgaa tagatacttg aatagattta ttaacacatt
    25441 tcactgaaaa gtatagcgaa aatattcaag ctggagagaa aaatgaatag atgctaaaaa
    25501 accggagcgg tctcccgctc cggcttcaca cgacaatcgc ctttcagcga aacacaatta
    25561 ctctttatcg cccagcagaa cggattccag tgcgattttg atcatgtcgt tgaaggtagt
    25621 ctgacgctca gcggcagtgg tctgctcgtg cgtgcggata tggtcagata cggtgcagat
    25681 ggtcagggct ttcgcgccga attctgcagc gacgccgtag ataccagctg cttccatttc
    25741 cacgccgagg atgccgtatt tttccatcac gtcgaacatt tcgccgtccg gagagtagaa
    25801 caggtcagcg gagaacaggt taccaacgcg agcatcaatg cccagtgctt tagctgcatc
    25861 taccgcgtta cgcaccatgt cgaagtcagc gatagctgca aagtcatggt ctttaaaacg
    25921 gatgcggtta actttggaat cggtgcaggc ccccatacca atcactacgt cacgcagttt
    25981 tacgtgcggc agaactgcac cacaggaacc aacgcgaatg attttcttca cgccgaaatc
    26041 ggtgatcagt tctttagtgt agatggagca ggacgggata cccataccgt ggcccattac
    26101 agaaattttg cggcctttgt aagtaccggt gaaacccagc ataccgcgaa cgttgttcac
    26161 ttcacgggca tcttcaagga aagtttcagc aatatacttc gcacgcagcg ggtcgcctgg
    26221 catcaaaact acgtcagcga aatcgcccat ttctgcatta atgtgtggag tagccatcat
    26281 tttatccttt ttgtgacata ttaaaggcgg agtcactgct ccgcccaaat ccatcagaac
    26341 atggctttgc catattccat atcagaagta ccaaaatatt ttgccagagt ctggccgata
    26401 tccgcgaaag tttcacggtg ccccagcgaa cccggtttta ctttcgggcc gtaaaccagt
    26461 accggaatgt gttcacgggt atggtcagta ccggtccagg tcggatcaca accgtggtca
    26521 gcggtgagga tcaggatgtc gtcatcgcgc agcaaagaca tcagctctgg cagacggcgg
    26581 tcgaacagtt ccagacccgc cgcataacct gcgacgtcgc gacggtgccc ccaggaagag
    26641 tcgaagtcaa caaagttggt gaagacgatg gtgttatcac ccgcttcttt catctcttta
    26701 atggtggcgt caaacagcgc gtccaggccg gtcgctttca cttttttggt gatgccgcag
    26761 ttagcgtaga tgtctgcaat tttaccgaca gaaaccacct ggccgtgttt ttcatcaacc
    26821 agtttctgca gcacggtcgg tgccggcggt tcaacagcca ggtcgtgacg gttgccagta
    26881 cgctggaagt taccggcttt atcgccgata aacgggcgag cgataacacg accgatgttg
    26941 tagccgccgt tggtcagctc ttcacgggcg atttcacaca gttcgtagag tttatccaga
    27001 ccgaaagttt cttcatggca ggcaatctgg aacacggagt cagcggaggt atagaaaatc
    27061 ggcttgccgg ttttcatgtg ctcttcgccc agctgatcca gaatgaccgt accggaggag
    27121 tggcagttac cgaggtaacc cggcagatta gcgcgttcga ccagtttatc cagtagctct
    27181 tgagggaagc tgttttcgtg atcggagaag tatccccact caaacagaac cgggacaccg
    27241 gcgatttccc agtgaccaga cggggtgtct ttaccggatg acatttcgtg cgcccatgcg
    27301 tacgcgccga taacttcagc gttgccgtcc attcccgccg gaatgaaacc ggtagaacct
    27361 tcgtgtgctt tcgccaaccc cagacgggtc agatttggca gattgagcgg gcctttacga
    27421 ccattatcag cttcgccttt ggcacaagct tctgcgatat gacccagggt gtcagccccg
    27481 acgtcaccaa agcgttctgc atcttctgta gcgccgatgc cgaatgagtc cagcaccata
    27541 ataaatgcac gtttcatatg ttctccgtac tcagtgcttc aaatttaaat gatcagatca
    27601 gtataccgtt attcgctgat acggcgatag acagttggtg tgctttccgg tgctttatcg
    27661 gcaagtttaa ttgccgcttt caccgctttc gccgcttcct gccagctgtt ttcgtctttc
    27721 gcgtggataa ccgccagcgg acgctgaccg tctacctggt cacccaaacg cgccatatca
    27781 gtaaagccga cgctgtaatc gatggtgtca gatgcctgac ggcgaccgcc gcccattgca
    27841 accactgcca ttcccagcgc gcgggtatcc atatcactga caaaaccttc ggtatcagca
    27901 tagactgctt tcgtcagcat cgctgtcggc agatacttcg cgtagttctc aacgaagtcg
    27961 gtcgggcctt tttgtgccgc taccatacga ccaaagactt ctgccgcttt accgttgtcc
    28021 agtaccgcct gcaatttcgc gcgcgcttcg gcgtcatctt tcgccagttt gccggaggta
    28081 agcatctcca cacacaacgc catcgtgaca tcaaacagac gcgggttacg gtactcacct
    28141 gtcaggaact gcaccgcttc acgtacttca accgcgttac cggcactgga ggccagcacc
    28201 tgattcatgt cggtgagtag cgcggtggtg cgcacgccag cgccgttagc cacgccaaca
    28261 atcgcttcgg caagggcttc agagagttcg taggtcggca taaatgcacc gctaccgact
    28321 ttcacgtcca tcaccagtgc atccagacct tccgccagtt tcttcgccag gatcgaggca
    28381 gtgatcagcg ggatggaatc cacggttgcg gtaatatcgc gggtcgcata gaaacgttta
    28441 tccgccggag ccagtgaact ggtctggcca ataatcgcca cgccgacgtc tttaataatt
    28501 tcgcggaaac ggttgtcatc tgggaagatg tcgaagccag ggatggattc cagtttgtcg
    28561 agcgtaccac cagtatggcc gaggccgcga ccggagatca tcggaatata gccgccgcag
    28621 gcagcgacca ttggccccaa catcagcgaa gtcacatcgc cgacgccgcc ggtcgagtgt
    28681 ttatcaacaa tcgggccatt cagatgcagg cttttccagt cgagaacggt tcctgaatct
    28741 cgcatcgcca tcgtcagcga gacacgctcc ggcattgtca tatcgtggaa gaaaatggtc
    28801 atcgcgaggg cggcaatctg cccttcggag atagtgttgt cgcgaatgcc gttgataaag
    28861 aagcgaattt cttcatcgct cagcgcatga ccatcacgtt ttttacgaat aatttcttgt
    28921 gcgagaaaca aggtaacctc ccgtggaata agtttgaagg cgttgttgcc agatggcgga
    28981 tgttgttatt gcctgatgcg atgctgacgc atcatacaag gcctacacgg cactcgaccc
    29041 gtaggccgga taaggcgttc cgccgcatcc ggcatccacc ctctggcaaa aggcagctta
    29101 gtagctgctg gtgctcttac cgtcgccgtg gcccagagct ttcagcaggc ttgccagcag
    29161 gctggaagca ccaaagcggt aatgacgcgc atcagcccag tcagcaccga acagttcatc
    29221 tgcgatggca agatatttct gcgcatcttc cgcagtacgc acgccgcccg ccggtttgaa
    29281 accaacggtt ttctctacgc ccatatcacg gatcacttcc atcatgatgc gcgcgctttc
    29341 cggcgtcgcg ttcactgcta ctttaccagt agaggttttg atgaaatcag cacccgcttt
    29401 gatggatatt tcagacgctt tacggatcag cgcttcgtct ttcagttcgc cggtttcaat
    29461 aatcactttc agcagtacgt tcgctgctgc gcaagcctct ttacaggctt tcaccagatc
    29521 aaaaccaacc tgctcgttac ccgccatcag tgcacggtac gggaacacca catcaacttc
    29581 atcggcaccg taggcgattg ccgcgcgagt ttcggccagc gcgatttcga tatcgtcgtt
    29641 accgtgtggg aagttggtta ccgtagcgat acggatttcc ggggtgccct gctctttcag
    29701 cgttttgcga gcaatcggga taaagcgagg atagatacag atagcggcgg tattaccgac
    29761 cggagttttg gcctgatgac acagggcgat cactttctcg tcggtatcgt cgtcattcag
    29821 ggtggtcagg tccatcaatt tcagtgcacg caggctgctt gctttcagat cagtcatttc
    29881 attctcctgg cttgtcgcca ataaaattca ccttgcgagt ttgttagtat tctaacatcg
    29941 actccgcaac acacttcgat atacatcaca attaaggaaa tctacttaca aaattgcatt
    30001 actgtaatgc gatctggttc aaataattca ctttcaaatg aatgcgtcag tggtggcaaa
    30061 cgcatcagga tcaaagtgaa catcacgaaa cttcttacaa tggcgcatca ccttcggcat
    30121 aaaaaggaac agaagatgcc cacttctcat gaaaatgcac tgcaacaacg ttgccagcaa
    30181 attgtcacca gcccagtgct tagcccggag cagaagcgcc attttctggc actggaagca
    30241 gaaaacaatc tgccttaccc acagctgcct gccgaagccc gccgcgcgct ggatgaaggt
    30301 gtaatctgcg atatgtttga aggtcatgcg ccgtacaaac cgcgctatgt cttacccgat
    30361 tacgcccgtt ttctggcgaa cggttccgaa tggctggagc tggaaggcgc gaaagatctt
    30421 gatgacgcac tctctctgct gaccattctt taccaccacg taccgtcggt cacatcgatg
    30481 ccggtctacc tggggcaact ggatgcgttg ttgcaaccgt atgttataat tctaacacaa
    30541 gacgagatcg atgttcgaat aaaacgtttc tggcgttacc tcgacagaac cctgccagac
    30601 gcctttatgc acgccaatat cggcccgtct gattcgccca ttacccgcgc gatcttacgt
    30661 gcagacgcag agttgaagca ggtttcaccg aacctgacct ttatctacga tcctgaaatc
    30721 acccctgatg acctgctgct ggaagtggcg aagaacatct gtgaatgtag caaaccgcac
    30781 atcgccaacg gtccggtgca tgataaaatt ttcacaaaag ggggctacgg gattgtgagc
    30841 tgttacaact cactgccgct ggcgggtggt ggtggcacgc tggtacgcct taacctgaaa
    30901 gccattgccg agcgcagcga atcgctggat gacttcttta cgcgcactct accgcactac
    30961 tgccagcagc agatcgccat catcgatgcg cggtgtgaat tcctctatca acaatcacac
    31021 ttctttgaga atagcttcct ggtgaaagaa gggctgatta accctgaacg ttttgtgcca
    31081 atgtttggca tgtatgggct ggcggaagcg gttaacttgc tgtgtgagaa agaagggatt
    31141 gccgcgcgct acggtaaaga agccgccgca aatgaagtgg gttatcgcat cagcgcgcaa
    31201 ctggcggagt ttgtcgccaa tacccccgtg aaatatggct ggcaaaaacg cgccatgtta
    31261 cacgcacagt cggggatcag ttccgatatt ggcaccacgc cgggcgcgcg tttgccgtat
    31321 ggcgatgagc cagatccgat cacccatctg caaactgtcg ccccgcatca tgcttattat
    31381 tattccggca tcagcgacat tctgacgctc gacgaaacca tcaaacgtaa cccgcaggca
    31441 ctggtacagc tttgcctcgg tgcctttaaa gccggaatgc gtgaatttac cgccaatgtc
    31501 agcggtaacg atctggttcg cgttaccggt tatatggtac gtttgtcgga cttagaaaaa
    31561 tatcgcgccg aaggttcacg caccaacacc acctggctgg gcgaagaagc cgcacgcaac
    31621 actcgtattc tggaacgcca gccgcgcgtg ataagccatg aacagcagat gcgctttagt
    31681 cagtaagatt atccccttct cctgcgttga cgggccaggc agtcgtctgg ctctgttttt
    31741 gcagggctgc aatctgcgct gcaaaaactg tcacaatccg tggacgatgg gacgctgcaa
    31801 tgattgcgga gagtgcgtgc cacagtgtcc gcatcaggcg ttgcagattg ttgacggcaa
    31861 agtgctgtgg aacgctgtgg tctgcgagca gtgtgatacc tgcctgaaga tgtgtccgca
    31921 acatgccacg ccaatggcgc aatccatgag cgtggacgaa gtgcttagcc atgtccgcaa
    31981 agcggtgctg tttattgaag ggataacggt aagcggcggc gaagccacga cccaactgcc
    32041 gtttgtagtg gcgctgttta ctgctatcaa aaacgatccg caactgcgcc acctcacctg
    32101 cctggtggac agtaacggta tgttgagcga aaccggctgg gaaaaattac tcccggtgtg
    32161 cgacggcgca atgctcgatc tcaaagcgtg ggggagcgaa tgtcatcagc aattaaccgg
    32221 acgcgataat cagcagatta agcgcagcat ctgtttgctg gcagagcgcg gtaagctggc
    32281 ggaactgcgt ttgctggtaa ttccagacca ggtggattat ttgcatcaca tcgatgagct
    32341 ggcgacgttt atcaagagac ttggcgatgt tccggttcgc ctgaatgcgt ttcatgccca
    32401 cggcgtgtat ggcgaggcgc aaagctgggc gagcgccacg ccggaagacg ttgagccgtt
    32461 ggctgatgcg ttaaaggtgc gcggggtgag ccggttgata tttccggcgc tctatttgtg
    32521 acatgccgga tacggcctac ggttcggcac agacttgtag gcatgataag acgcgacaag
    32581 cgtcgcatca ggcattatgc gccgactgcc ggatgcggcg tgaacgcctt atccggccta
    32641 cggttcggca cagacttgta ggcatgataa gacgcgtcag cgtcgcatca ggcattgtgc
    32701 gccaactgcc ggatgcggcg tgaacgcctt atccggccta cggttcggca cagacttgta
    32761 ggcatgataa gacgcgtcaa gcgtcgcatc aggcattgtg cgccaactgc cggatgcggc
    32821 gtgaacgcct tatccggcct acggttcggc acaaacctgt aggcatgata agacgcgtca
    32881 agcgtcgcat caggcattgt gcgccaactg ccggatgcgg cgtgaacgcc ttatccggcc
    32941 tacggttcgg cacaaacctg taggcatgat aagacgcgac aagcgtcgca tcaggcatta
    33001 tgcgccgact gccggatgct gcctacgaag ggtaaactac ccacgaacgc taaacaccgc
    33061 atacgtatta ttaagcaaca cttcggcaat ctcatcttct ggttccgggc gcaactcgca
    33121 aagcacgtca aacacccgtg cagcctgttc cgggcggtta ggctgcccct gaaagccgtt
    33181 gagcggcata tccggcgcgt cggtttccag caacaacgat gccagcggta attttgcgat
    33241 gacatcgcgg gttttactgg cgcgtggata ggtgatagta ccgcctacgc cgattttgta
    33301 gcccaactgt acaaaccgct cggcctgttg caggctgccg gaaaaaccgt gaaccacgcc
    33361 agtgcgcgat aaatcgtggc gtttaagatg catcgccaat ttgtcgtgtg tgcgccgtga
    33421 atgcaggatc accggcagat cgtagcgttt cgccagtttc agttgttcgt cgagtaacca
    33481 ctgctgcctc tcaaattgcg gatcgtcgcc gaagagatcc agaccgatct cccccaccgc
    33541 caccaccttc gccggacgcc tttccagcgc ctgctgtagc tgatcaagag acacatcgct
    33601 atgtttttcc aacataccag gatgcaagcc caatgcggca tacagcggtt gatatttttc
    33661 cgctaacgcc tgcacacggg caaaattttc cgcctctgtc gccggaacaa tgatcttgcc
    33721 tacgcccgct tgtgccgcgc gttgcaggct ggcctcttca tcgccactaa acggcgggaa
    33781 atcaaaatgg cagtgggtgt cgataaaacg gcaaatcaag ccagatcctc attgttaaat
    33841 gtcgggtcgt tcgcctgcgg agcgtcaatc acttcggcaa ccagcgtatc gttggcgact
    33901 ggcgcaggcg gaatgacaat cgattccggc gtcaccactg gcaccagatg gcgggtaagc
    33961 ggcgcttttt cagttaatag cttgccaacc gtggcgagga aataacgacc gcataaacgc
    34021 ccaagtttat agtcttcacg cagcgccgga atccgactgc caagcgcgat actatgtaat
    34081 ggcttcggtg gataaatttc gaatatccgc agcttgcccg gtggtttctc aataaattgc
    34141 tgaatgtcac gatagctggt ttcatgatgc tgcaccagat tgaccagcgg ctgcaggcta
    34201 ctgtcaccca gccagcgttc catgcgtttg aaccactgcg gcgtgtagta catttgtgac
    34261 ggcacagtgc gaatgacgac caacgtttta gcgccctgcc ttgccgcctc tttaaccgga
    34321 atcgcatcac tgatcccgcc atccaggtag ttaatgcctt ccagcgacac tccgctacga
    34381 taaaagccag gtatcgcact ggaggcgcga atcacatcca gccagttttg tttggttggt
    34441 aaaaagtaat tcggcgcgta gtcatcctga cgacaggcgc acatataaaa cgatttgccg
    34501 ctgtcaaaca accgcgcggc ggtatccatt tgcaacggca tctggcttgc agtggcctcc
    34561 accagccagt cgagatcgat aagatttcct ccacggacaa agcgcaatgg atcgaaaaat
    34621 tcgcgttttg tggtatagcg catgatgact ttgcgcgcgt aaccgggctg attgcagata
    34681 aacgccgaga ggttctgcgc cccggcagat gtgccgagat aaagatcgaa aggattaaac
    34741 tgcgcgcgca taaactcatc cagcacgcca gccgtgaaaa ttccacgctg tccgccgcct
    34801 tcgcacacca gagctattcg tccaggctgg aacggcctta gcgacaacgg cgcaatatta
    34861 ccaagcgtta caggtattcg ctgccccacc tctgccttcc tgtttttgtt gtgaaagaat
    34921 gacaaagtaa cgcaatttat tattcgctaa aaccgcaaaa gccagtccgc tggactggct
    34981 ttggataaaa ttttcttaat ggtctgaaat ctagggtcgt tttcggccca tgaacaaact
    35041 caccaggaac agaataatcc cgacgacaaa gacaatttta gctgcgcctg cagcggtacc
    35101 ggccagacca ccaaacccaa gtgcggcggc gattaacgcg ataaccagaa atatgatgcc
    35161 ccaacgaaac ataagcgtct cctttaccat agttaatgtc accgcttgat atgagcgtga
    35221 aaatcactca atgcgatatt tttagtgtgg tgcacatcgc gcctcccgac aaagttcggg
    35281 aggacgaatt acgacgaatt acttagtttt cagatcattt ttaacgcttt tcacaccatc
    35341 taccgctttg gcgatacttt cagcacggtc actttgtgcc tgagaatcta cggtaccgga
    35401 gagctgaacc acaccatcgg tggtttcaac tttcacttta cgtgaaggaa cgatatcgtc
    35461 cgccagcagt ttggctttga tttcactggt ggtggcggtg tcacccgcgt agcccttcac
    35521 agagccttct ttagcgtcgc gaacgtgcag tttgtcgctg acagaggtca cgccttcaac
    35581 gcctttggcc actttcactg cctcttcggc ctgagcctgg ctttcaacga aaccgctcag
    35641 ggtcacgact ttttgatcgg ttttgacaga gatatcggtg ctcttgatgt tgtcatgatc
    35701 caccagggcc gccttcactt tcgcggtgat ggcgctgtca tccatgaaat taccgacttt
    35761 attcatagag ctatcgactt tttgccctgc gctttcattg gtagtctgcg cgttgttttc
    35821 cgcgtaggca gagccggtcg cgacggcaga ggtcaacatt acagccagca gagttttcga
    35881 aatcttcagt cttgtcatag tcatcgattt attcctgtat gtttgctcat aatttgagcc
    35941 tggcaacacg aggttgcatt gctgaatagg gagagacttc accctctaca gaagtcaatg
    36001 gccgccatca caaaagcgat gggtgatgaa taacgaccat tacagcctct gaatcagtta
    36061 ttaatatcgg tagaatgaca atcgacggct ttagatactg atatctacgc attgaacggt
    36121 atttaacgcc gtcagaaatg tcattacttt gttaaatata gatcacaatt ttgaaaccgc
    36181 tcgggatatc agctaaaaca taagcaaaag tgaatgtttt aagaacattc cgtaagcggc
    36241 taataaggaa gggaaattga cagggcgcag cggctaccgc gccctggagg caagaattaa
    36301 tgctcgcggg tctggtggaa ctgaacgtcc ggataacgtt cctgcgccag gcgcaggttt
    36361 accatgctgg tagcgatgta agcgaggtta tcgccgccat caagcgccag ttggctttcg
    36421 ttcttacgct tgaactcttc gaatttcttc gcgtccgcac attctaccca gcgggcagtg
    36481 gcaacgttga ctgactcata cactgcttca acgttgtatt cgctcttcag gcgcgatacc
    36541 accacatcaa actgcagcac accaactgca ccaacgatca ggtcgttgtt ggagatcgga
    36601 cggaacacct gcaccgcgcc ctcttcggaa agctgtacca gccctttgag cagctgtttt
    36661 tgcttcagcg gatctttcag gcggatacga cggaacagtt ccggcgcgaa gttcggaata
    36721 ccagtgaact tcatcatctc accctgggta aaggtgtcgc cgatctgaat agtgccgtgg
    36781 ttatgcaggc cgaggatatc gcccggatac gcttcttcaa cgtgcgaacg gtcgcccgcc
    36841 ataaaggtca gcgcgtcgga gatcaccaca tctttcgcag tgcgcacctg gcgcagcttc
    36901 atgccttttt catatttacc ggataccacg cgcataaacg ccacgcggtc acggtgtttc
    36961 gggtccatgt tggcctgaat tttaaatacg aagccggtaa atttgtcttc gctcgcttct
    37021 acagtacggg tatcagtctg acgcggcatc ggcgcaggtg cccactccac caggccatcc
    37081 agcatatgat caacgccgaa gttacccagc gcagtaccga agaataccgg agtgatttcg
    37141 cccgcaagga acaattcttt gtcgaactcg ttagacgcgc ctttcaccag ctccagttca
    37201 tcacgcagct gctgcgccag atcttcacca accgcagcgt cgagatccgg gttattcagc
    37261 cctttaacaa tgcggacttc ctgaatggtg tggcctttac cgctctgata gagataggtt
    37321 tcatctttat aaaggtggta aacgccttta aacagcttgc cgcagccaat cggccaggtg
    37381 atcggtgcac agccgatttt cagctcgttc tcaacttcat cgagcagctc catcgggtcg
    37441 cggatatcac ggtcaagttt gttcataaag gtgaggatcg gcgtgtcgcg cagacgggta
    37501 acttccatca gcttgcgggt acgatcttca acaccttttg cagcgtcgat aaccatcagg
    37561 cagcagtcca ccgccgtcag ggtacgatag gtatcttccg agaagtcttc gtgccccggg
    37621 gtgtcgagca ggttaaccag gcagtcgtga tacggaaact gcatcacaga cgtggtaatg
    37681 gagatcccac gctgcttttc catctccatc cagtccgact tagcgtgctg gttagagcca
    37741 cggcctttta ctgtaccggc ggtctgaatg gcctgtccga acagcagcac cttctcggtg
    37801 atggtagttt taccggcgtc cgggtgagaa ataatggcaa aagtgcggcg cttcgccacc
    37861 tcttgcaaat aaggagacaa cgtcataatt ctttcttctt gagtaagcgg catcgcgccg
    37921 cgcttgttga aaacgaaaaa ttgcggctat tttacccatc aacggggggg aggcaatcag
    37981 tgtttacaca ggagctgctc cagttcgtgc aacgaagaaa cggtccaggt gggcgcgatg
    38041 ccttctggtt gctcgcgatt gtgcgcattc agccagcagg tcgcaagccc ggcgttgatg
    38101 ccaccgagaa tatcggactc ggcagtgtcg ccaaccatca gcacgcgtga acggtcagga
    38161 ttgcccgcct gttccagcgc ataatcgaaa attttcttat tcggtttagc aacgccaact
    38221 tcttcggaaa tcaccagcaa atcgaagtaa tcacgcaggc ccgtgcgttc cagacgcacc
    38281 tgttgcaagg cgctaaaacc gttggtgatg atgccgattt tggcgttgcc acgaatggcg
    38341 ttaagcagag aaaccgctcc cggcagcggc gtacagattt ccgccatcgc attaataaag
    38401 gcttcgttga gtttacccgg ctcgacgttc agccgttcgg cccagctctc aaaccgcccg
    38461 tgctgaagct gtaatgaagt gatcgcgccg ttttgataat ccacccacag tggcttgtta
    38521 acggcctgat agtcctgaaa atcttcagcg gtaaaggtga cgctgtaatc aagaaacatc
    38581 cgctgcaggc cggtgaatga gtcaaaggta aacagcgttt catcggcatc aaagaaaatc
    38641 cagtcccact tcattattcc accttgtctt acatactgat tggcaacgcc atgatgatgg
    38701 cgtcttcgcg accgtccgtg gtggggtagt aattgcggcg aatcgtcgcc tcgttaaagc
    38761 ctaaactttc gtacagtgca atggcggcag cgtttgaggc acggacttcc agccatagcg
    38821 tcgccacgcc gcgtttttcc agttcgtcga tcagatgttc cagcagcgcc cttcccagtc
    38881 cctgacgctg atagtcggga tcgaccgcaa tattgaacaa tgtagcttca tccagcacca
    38941 cttgcgtaat cgcaaacgcc gccattttgc cgttttgcgt taactgaaag ttgagataac
    39001 gctcgccctg gttgctggca aaggtttttt cactccacgg aaaggcgtgg gcgcgttgtt
    39061 caatgtggaa agccgctggt aaatcagtcg tttcgaggga agaaatcgtg ttcatatgtg
    39121 caaatttgtt gccataacgc ggcgcgtgcc gttgggtttg cccgtaattc ggtgagcgcc
    39181 ggtgatgcca cctgagcgcc ttccagtgat agcggttcgt cagtacccaa ccgccagctg
    39241 ttgcagcgac tgccttgcgg cagcatcgcg attttttctg gcgtcagttg cagcacttga
    39301 tcggggctga cggttaatgc gcgcagaaca tcgctcacta aaggatcagt cagggcggga
    39361 agatcgtttg ccaccatcac cagacggacg tgtgccggga tcgcaatggc aatctccccc
    39421 tgcaacgcgc cagggcgacg cagcgaccac tgggtaatgc ccagttgctg taactgccag
    39481 tctcgtcggg atgtcatagc gaatcgctcc tgttgtcagg ggcgcaaata tagcaaattc
    39541 gtcgataccg cgccaacata tggctataat cgccgccagt atcaattgag gagcattcca
    39601 tgtctgcatt taccccggca agtgaagtct tgctgcgtca cagtgatgat ttcgaacaaa
    39661 gccgtattct ttttgccgga gacttacagg atgacctgcc cgcgcgttta gataccgcgg
    39721 ccagccgtgc tcatacccag caattccacc actggcaggt gttaagccgc cagatgggtg
    39781 ataacgcccg ttttagtctg gtcgccacgg cggatgacgt cgcagattgc gatactttga
    39841 tttactactg gccgaagaac aaaccggaag cccagttcca gttgatgaat ttactttctc
    39901 tgctgccggt ggggacggat atttttgtcg ttggcgagaa ccgcagcggc gtgcgcagcg
    39961 ccgaacagat gctggcagat tatgcgccgt tgaataaagt cgacagcgcc cgtcgctgtg
    40021 gcctctattt tggtcgtctg gaaaaacagc cggtatttga tgccgataaa ttctggggcg
    40081 aatacagcgt cgatggcctg acggtcaaaa cgctgcctgg cgtgtttagc cgcgacggtc
    40141 tggatgtcgg tagccagttg ctgctctcga cgttaactcc gcacacgaaa ggtaaagtgc
    40201 tggatgtcgg cagcggcgcg ggcgtgcttt cggttgcctt tgcgcgccat tcaccgaaaa
    40261 ttcgtctcac tctgtgcgat gtctctgcgc cagcggtaga agccagccgc gcaacacttg
    40321 cggccaacgg tgttgaaggt gaagtctttg ccagtaacgt cttttccgag gtgaaaggtc
    40381 gttttgatat gatcatctcc aacccgccgt tccacgatgg gatgcaaacc agcctcgatg
    40441 cggcgcaaac gctgattcgc ggcgcggtgc gtcaccttaa cagcggcggc gagctgcgaa
    40501 ttgtagcgaa cgccttcctg ccttatccgg acgtgctgga tgagacattt ggcttccatg
    40561 aagtgatcgc gcaaaccggg cgcttcaagg tgtatcgcgc cattatgacc cgccaggcga
    40621 agaaaggtta agtatcccgc cgcaagcctt gtcggatgcg gcgtgctcgc cttatacaac
    40681 ctacaaaacc tgcacgttag cccttcgtag gccagataag acgcgcccgc gtcgcatctg
    40741 gcatctgcac ccaaataccg tgtcggatgc ggcgtgaacg ccttatccga cctacaaaac
    40801 ctgcacgtta gtttcctgat ggacattttt ccagcaatta cacctccggc gataattaac
    40861 tattgacgaa aagctgaaaa ccactagaat gcgcctccgt ggtagcaatt ctttttaaga
    40921 attgatggta tgcgaagg
//
LOCUS       DADXDL010000033        40897 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.033, whole genome shotgun sequence.
ACCESSION   DADXDL010000033 DADXDL010000000
VERSION     DADXDL010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40897)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40897)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40897
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.033"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            15..90
                     /locus_tag="IRB70_002079"
     tRNA            15..90
                     /locus_tag="IRB70_002079"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:48..50,aa:Lys,seq:ttt)
     gene            complement(201..1085)
                     /gene="xapR"
                     /locus_tag="IRB70_002080"
     CDS             complement(201..1085)
                     /gene="xapR"
                     /locus_tag="IRB70_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XapR"
                     /protein_id="HBC0631993.1"
                     /translation="MERVYRTDLKLLRYFLAVAEELHFGRAAARLNMSQPPLSIHIKE
                     LENQLGTQLFIRHSRSVVLTHAGKILMEESRRLLVNANNVLARVEQIGRGEAGRIELG
                     VVGTAMWGRMRPVMRRFLRENPNVEVLFREKMPAMQMALLERRELDAGIWRMATEPPT
                     GFTSLRLHESAFLVAMPEEHHLSSFSTVPLEALRDEYFVTMPPVYTDWDFLQRVCQQV
                     GFSPVVIREVNEPQTVLAMVSMGIGITLIADSYAQMNWPGVIFRPLKERIPADLYIVY
                     ETQQVTPALVKLLAALAQ"
     gene            complement(1127..1285)
                     /locus_tag="IRB70_002081"
     CDS             complement(1127..1285)
                     /locus_tag="IRB70_002081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1427 family protein"
                     /protein_id="HBC0631994.1"
                     /translation="MKDILFSSGVGFGIGALFTIVRLPIPVPNVLPGILSIVFMYVGY
                     LVVKYFMP"
     gene            complement(1338..2594)
                     /gene="xapB"
                     /locus_tag="IRB70_002082"
     CDS             complement(1338..2594)
                     /gene="xapB"
                     /locus_tag="IRB70_002082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine/proton symporter XapB"
                     /protein_id="HBC0631995.1"
                     /translation="MSIALRLKVMSFLQYFIWGSWLVTLGSYMINTLHFTGANVGMVY
                     SSKGIAAIIMPGIMGIIADKWLRAERAYMLCHLVCAGVLFYAASVTDPDMMFWVMLVN
                     AMAFMPTIALSNSVSYSCLAQAGLDPVTAFPPIRVFGTVGFIVAMWAVSLLHLELSSL
                     QLYIASGASLLLSAYALTLPKIPVAEKKATTSLASKLGLDAFVLFKNPRMAIFFLFAM
                     MLGAVLQITNVFGNPFLHDFARNPEFADSFVVKYPSILLSVSQMAEVGFILTIPFFLK
                     RFGIKTVMLMSMVAWTLRFGFFAYGDPSPTGFILLLLSMIVYGCAFDFFNISGSVFVE
                     QEVDSSIRASAQGLFMTMVNGVGAWVGSILSGMAVDYFSVDGVKDWHTIWLMFAGYAL
                     FLAVIFFFGFKYNHDPEKITHRSVTH"
     gene            complement(2654..3487)
                     /gene="xapA"
                     /locus_tag="IRB70_002083"
     CDS             complement(2654..3487)
                     /gene="xapA"
                     /locus_tag="IRB70_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthosine phosphorylase"
                     /protein_id="HBC0631996.1"
                     /translation="MYQAQFSHNPLYCVDIIKTYKPDFTPRVAFILGSGLGALADQIE
                     NAVAISYEKLPGFPVSTVHGHAGELVLGYLQGVPVVCMKGRGHFYEGRGMTIMTDAIR
                     TFKLLGCELLFSTNAAGSLRPEVGAGSLVALKDHINTMPGTPMVGLNDERFGERFFSL
                     ANAYDAEYRALLQKVAKEEGFPLTEGVFVSYPGPNFETAAEIRMMQIIGGDVVGMSVV
                     PEVISARHCELKVVAVSAITNMAEGLSDVKLSHAQTLAAAELSKQNFINLICGFLRKI
                     A"
     gene            3736..4500
                     /locus_tag="IRB70_002084"
     CDS             3736..4500
                     /locus_tag="IRB70_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0631997.1"
                     /translation="MKKHLFTLTLSSVLAIPAVSHAEFKGGFADIGIHYLDWTSRTTE
                     KSSTKSHKDDFGYLELEGGANFSWGEMYGFFDWENFYNNRHDKPGSEQRYTFKNTNRI
                     YLGDTGFNLYLHAYGTYGSANRVNFHDDMFLYGIGYNFTGSGWWFKPFFAKRYTDQTY
                     YTGDNGYVAGWVAGYSFMLGSEKFTLTNWNEYEFDRDATYAAGNGGKEGLNGAVALWW
                     NATSHITTGIQYRYADDKLGEDFYQDAIIYSIKFNF"
     gene            complement(4538..5464)
                     /locus_tag="IRB70_002085"
     CDS             complement(4538..5464)
                     /locus_tag="IRB70_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0631998.1"
                     /translation="MNYSLKQLKVFVTVAQEKSFSRAGERIGLSQSAVSHSVKELENH
                     TGVRLLDRTTREVVLTDAGQQLALRLERLLDELNSTLRDTGRMGQQLSGKVRVAASQT
                     ISAHLIPQCIAESHRRYPDIQFILHDRPQQWVMESIRQGDVDFGIVIDPGPVGDLQCE
                     AILSEPFFLLCHRDSALAAEDYVPWQALQGAKLVLQDYASGSRPLIDAALARNGIQAN
                     IVQEIGHPATLFPMVAAGIGISILPALALPLPEGSPLVVKRITPVVERQLMLVRRKNR
                     SLSTAAQALWDVVRGQGRALMAGREGDPLYQI"
     gene            5554..6552
                     /locus_tag="IRB70_002086"
     CDS             5554..6552
                     /locus_tag="IRB70_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bile acid:sodium symporter"
                     /protein_id="HBC0631999.1"
                     /translation="MKLFRILDPFTLTLITVVLLASFFPARGDFVPFFENLTTAAIAL
                     LFFMHGAKLSREAIIAGGGHWRLHLWVMCSTFVLFPILGVLFAWWKPVNVDPMLYSGF
                     LYLCILPATVQSAIAFTSMAGGNVAAAVCSASASSLLGIFLSPLLVGLVMNVHGAGGS
                     LEQVGKIMLQLLLPFVLGHLSRPWIGDWVSRNKKWIAKTDQTSILLVVYTAFSEAVVN
                     GIWHKVGWGSLLFIVVVSCVLLAIVIVINVFMARRLGFNKADEITIVFCGSKKSLANG
                     IPMANILFPTSVIGMMVLPLMIFHQIQLMVCAVLARRYKRQTEQLQAQQESSANKA"
     gene            complement(6549..6767)
                     /locus_tag="IRB70_002087"
     CDS             complement(6549..6767)
                     /locus_tag="IRB70_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3820 family protein"
                     /protein_id="HBC0632000.1"
                     /translation="MEKEQLIEIANTIMPFGKYKGRRLIDLPEEYLLWFARKDEFPAG
                     KLGELMQITLLIKTEGLTQLVQPLKRPL"
     gene            complement(6769..8784)
                     /gene="ligA"
                     /locus_tag="IRB70_002088"
     CDS             complement(6769..8784)
                     /gene="ligA"
                     /locus_tag="IRB70_002088"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBC0632001.1"
                     /translation="MESIEQQLTELRTTLRHHEYLYHVMDAPEIPDAEYDRLMRELRE
                     LETKHPELITPDSPTQRVGAAPLAAFSQIRHEVPMLSLDNVFDEESFLAFNKRVQDRL
                     KSNEKVTWCCELKLDGLAVSILYENGVLVSAATRGDGTTGEDITSNVRTIRAIPLKLH
                     GENIPARLEVRGEVFLPQAGFEKINEDARRTGGKVFANPRNAAAGSLRQLDPRITAKR
                     PLTFFCYGVGVLEGGELPDTHLGRLLQFKKWGLPVSDRVTLCESAEEVLAFYHKVEED
                     RPTLGFDIDGVVIKVNSLAQQEQLGFVARAPRWAVAFKFPAQEQMTFVRDVEFQVGRT
                     GAITPVARLEPVHVAGVLVSNATLHNADEIERLGLRIGDKVVIRRAGDVIPQVVNVVL
                     SERPEDTREVVFPTHCPVCGSDVERVEGEAVARCTGGLICGAQRKESLKHFVSRRAMD
                     VDGMGDKIIDQLVEKEYVHTPADLFKLTAGKLTGLERMGPKSAQNVVNALEKAKETTF
                     ARFLYALGIREVGEATAAGLAAYFGTLEALEAASIEELQKVPDVGIVVASHVHNFFAE
                     ESNRNVISELLAEGVHWPAPVVINAEEIDSPFAGKTVVLTGSLSQMSRDDAKARLVEL
                     GAKVAGSVSKKTDLVIAGEAAGSKLAKAQELGIEVIDEAEMLRLLGS"
     gene            complement(8855..9853)
                     /gene="zipA"
                     /locus_tag="IRB70_002089"
     CDS             complement(8855..9853)
                     /gene="zipA"
                     /locus_tag="IRB70_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZipA"
                     /protein_id="HBC0632002.1"
                     /translation="MMQDLRLILIIVGAIAIIALLVHGFWTSRKERSSMFRDRPLKRM
                     KSKRDDDSYDEDVEDDEGVGEVRVHRVNHAPANAQEHEAARPSPQHQYQPPYASAQPR
                     QPVQQPPEAQVPPQHAPRPAQPVQQPVQQPAYQPQPEQPLQQPVSPQVASAPQPVHSA
                     PQPAQQAFQPAEPVAAPQPEPVAEPAPVMDKPKRKEAVIIMNVAAHHGSELNGELLLN
                     SIQQAGFIFGDMNIYHRHLSPDGSGPALFSLANMVKPGTFDPEMKDFTTPGVTIFMQV
                     PSYGDELQNFKLMLQSAQHIADEVGGVVLDDQRRMMTPQKLREYQDIIREVKDANA"
     gene            10083..10844
                     /gene="cysZ"
                     /locus_tag="IRB70_002090"
     CDS             10083..10844
                     /gene="cysZ"
                     /locus_tag="IRB70_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate transporter CysZ"
                     /protein_id="HBC0632003.1"
                     /translation="MVSSFTSAPRSGFYYFAQGWKLVSQPGIRRFVILPLLVNILLMG
                     GAFWWLFTQLDVWIPTLMSYVPDWLQWLSYLLWPLAVISVLLVFGYFFSTIANWIAAP
                     FNGLLAEQLEARLTGATPPDTGIFGIMKDVPRIMKREWQKFAWYLPRAIVLLILYFIP
                     GIGQTVAPVLWFLFSAWMLAIQYCDYPFDNHKVPFKEMRTALRTRKITNMQFGALTSL
                     FTMIPLLNLFIMPVAVCGATAMWVDCYRDKHAMWR"
     gene            11029..12000
                     /gene="cysK"
                     /locus_tag="IRB70_002091"
     CDS             11029..12000
                     /gene="cysK"
                     /locus_tag="IRB70_002091"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBC0632004.1"
                     /translation="MSKIFEDNSLTIGHTPLVRLNRIGNGRILAKVESRNPSFSVKCR
                     IGANMIWDAEKRGVLKPGVELVEPTSGNTGIALAYVAAARGYKLTLTMPETMSIERRK
                     LLKALGANLVLTEGAKGMKGAIQKAEEIVASNPEKYLLLQQFSNPANPEIHEKTTGPE
                     IWEDTDGQVDVFIAGVGTGGTLTGVSRYIKGTKGKTDLISVAVEPTDSPVIAQALAGE
                     EIKPGPHKIQGIGAGFIPANLDLKLVDKVIGITNEEAISTARRLMEEEGILAGISSGA
                     AVAAALKLQEDESFTNKNIVVILPSSGERYLSTALFADLFTEKELQQ"
     gene            12384..12641
                     /gene="ptsH"
                     /locus_tag="IRB70_002092"
     CDS             12384..12641
                     /gene="ptsH"
                     /locus_tag="IRB70_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003038086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein Hpr"
                     /protein_id="HBC0632005.1"
                     /translation="MFQQEVTITAPNGLHTRPAAQFVKEAKGFTSEITVTSNGKSASA
                     KSLFKLQTLGLTQGTVVTISAEGEDEQKAVEHLVKLMAELE"
     gene            12686..14413
                     /gene="ptsI"
                     /locus_tag="IRB70_002093"
     CDS             12686..14413
                     /gene="ptsI"
                     /locus_tag="IRB70_002093"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate-protein phosphotransferase
                     PtsI"
                     /protein_id="HBC0632006.1"
                     /translation="MISGILASPGIAFGKALLLKEDEIVIDRKKISADQVDQEVERFL
                     SGRAKASAQLETIKTKAGETFGEEKEAIFEGHIMLLEDEELEQEIIALIKDKHMTADA
                     AAHEVIEGQASALEELDDEYLKERAADVRDIGKRLLRNILGLKIIDLSAIQDEVILVA
                     ADLTPSETAQLNLKKVLGFITDAGGRTSHTSIMARSLELPAIVGTGSVTSQVKNDDYL
                     ILDAVNNQVYVNPTNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIG
                     TVRDVEGAERNGAEGVGLYRTEFLFMDRDALPTEEEQFAAYKAVAEACGSQAVIVRTM
                     DIGGDKELPYMNFPKEENPFLGWRAIRIAMDRKEILRDQLRAILRASAFGKLRIMFPM
                     IISVEEVRALRKEIEIYKQELRDEGKAFDESIEIGVMVETPAAATIARHLAKEVDFFS
                     IGTNDLTQYTLAVDRGNDMISHLYQPMSPSVLNLIKQVIDASHAEGKWTGMCGELAGD
                     ERATLLLLGMGLDEFSMSAISIPRIKKIIRNTNFEDAKVLAEQALAQPTTDELMTLVN
                     KFIEEKTIC"
     gene            14454..14963
                     /gene="crr"
                     /locus_tag="IRB70_002094"
     CDS             14454..14963
                     /gene="crr"
                     /locus_tag="IRB70_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015833547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBC0632007.1"
                     /translation="MGLFDKLKSLVSDDKKDTGTIEIIAPLSGEIVNIEDVPDVVFAE
                     KIVGDGIAIKPTGNKMVAPVDGTIGKIFETNHAFSIESDSGVELFVHFGIDTVELKGE
                     GFKRIAEEGQRVKVGDTVIEFDLPLLEEKAKSTLTPVVISNMDEIKELIKLSGSVTVG
                     ETPVIRIKK"
     gene            complement(15006..15857)
                     /gene="pdxK"
                     /locus_tag="IRB70_002095"
                     /gene_synonym="thiJ"
     CDS             complement(15006..15857)
                     /gene="pdxK"
                     /locus_tag="IRB70_002095"
                     /gene_synonym="thiJ"
                     /EC_number="2.7.1.35"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxine/pyridoxal/pyridoxamine kinase"
                     /protein_id="HBC0632008.1"
                     /translation="MSSLLLFNDKSRALQADIVAVQSQVVYGSVGNSIAVPAIKQNGL
                     NVFAVPTVLLSNTPHYDTFYGGAIPDEWFSGYLRALQERDALRQLRAVTTGYMGTASQ
                     IKILAEWLTALRKDHPDLLIMVDPVIGDIDSGIYVKPDLPEAYRQYLLPLAQGITPNI
                     FELEILTGKNCRDLDSAIAAAKSLLSDTLKWVVITSASGNEENQEMQVVVVSADSVNV
                     ISHSRVKTDLKGTGDLFCAQLISGLLKGEALTDAVHRAGLRVLEVMRYTQQHESDELI
                     LPPLAEA"
     gene            15962..16330
                     /locus_tag="IRB70_002096"
     CDS             15962..16330
                     /locus_tag="IRB70_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfeK family protein"
                     /protein_id="HBC0632009.1"
                     /translation="MKKIICLVVTLLMTLPAYAKLTAHEEARINAMLEGLAQKKDLIF
                     VRNGDEHTCDEAVSHLRLKLGNTRNRIDTAEQFIDKVASSSSITGKPYIVKMPGKSDE
                     NAQPFLHALIAQTDKTVPAQ"
     gene            complement(16333..17244)
                     /gene="cysM"
                     /locus_tag="IRB70_002097"
     CDS             complement(16333..17244)
                     /gene="cysM"
                     /locus_tag="IRB70_002097"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase B"
                     /protein_id="HBC0632010.1"
                     /translation="MSTLEQTIGNTPLVKLQRMGPNNGSEVWLKLEGNNPAGSVKDRA
                     ALSMIVEAEKRGEIKPGDVLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAA
                     MRAYGAELILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPDNPYAHYTTTGPEIWQ
                     QTGGRITHFVSSMGTTGTITGVSRFMREQFKPVTIVGLQPEEGSSIPGIRRWPAEYLP
                     GIFNASLVDEVLDIHQREAENTMRELAVREGIFCGVSSGGAVAGALRVAKANPGAVVV
                     AIICDRGDRYLSTGVFGEEHFSQGAGI"
     gene            complement(17378..18475)
                     /gene="cysA"
                     /locus_tag="IRB70_002098"
     CDS             complement(17378..18475)
                     /gene="cysA"
                     /locus_tag="IRB70_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter ATP-binding
                     protein CysA"
                     /protein_id="HBC0632011.1"
                     /translation="MSIEIANIKKSFGRTQVLNDISLDIPSGQMVALLGPSGSGKTTL
                     LRIIAGLEHQTSGHIRFHGTDVSRLHARDRKVGFVFQHYALFRHMTVFDNIAFGLTVL
                     PRRERPNAAAIKAKVTKLLEMVQLAHLADRYPAQLSGGQKQRVALARALAVEPQILLL
                     DEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEATEVADRVVVMSQGNIEQA
                     DAPDQVWREPATRFVLEFMGEVNRLQGTIRGGQFHVGAHRWPLGYTPAYQGPVDLFLR
                     PWEVDISRRTSLDSPLPVQVLEASPKGHYTQLVVQPLGWYDEPLTVVMRGDDAPVRGD
                     RLFVGLQHARLYNGDERIETRDEELALAQSA"
     gene            complement(18465..19340)
                     /gene="cysW"
                     /locus_tag="IRB70_002099"
     CDS             complement(18465..19340)
                     /gene="cysW"
                     /locus_tag="IRB70_002099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026168.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysW"
                     /protein_id="HBC0632012.1"
                     /translation="MAEVTQLKRYDARPINWDKWFLIGIGMLVSAFILLVPMIYIFVQ
                     AFSKGLMPVLQNLADPDMLHAIWLTVMIALIAVPVNLVFGILLAWLVTRFNFPGRQLL
                     LTLLDIPFAVSPVVAGLVYLLFYGSNGPLGGWLDEHNLQIMFSWPGMVLVTIFVTCPF
                     VVRELVPVMLSQGSQEDEAAILLGASGWQMFRRVTLPNIRWALLYGVVLTNARAIGEF
                     GAVSVVSGSIRGETLSLPLQIELLEQDYNTVGSFTAAALLTLMAIITLFLKSMLQWRL
                     ENQEKRAQQEEHHEH"
     gene            complement(19340..20173)
                     /gene="cysT"
                     /locus_tag="IRB70_002100"
     CDS             complement(19340..20173)
                     /gene="cysT"
                     /locus_tag="IRB70_002100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000458418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter permease
                     CysT"
                     /protein_id="HBC0632013.1"
                     /translation="MFAVSSRRVLPGFTLSLGTSLLFVCLILLLPLSALVMQLSEMSW
                     AQYWEVITNPQVVAAYKVTLLSAFVASIFNGVFGLLMAWILTRYRFPGRTLIDALMDL
                     PFALPTAVAGLTLASLFSVNGFYGEWLAKFDIKVTYTWLGIAVAMAFTSIPFVVRTVQ
                     PVLEELGPEYEEAAETLGATRWQSFCKVVLPELSPALVAGVALSFTRSLGEFGAVIFI
                     AGNIAWKTEVTSLMIFVRLQEFDYPAASAIASVILAASLLLLFSINTLQSRFGRRVVG
                     H"
     gene            complement(20173..21189)
                     /gene="cysP"
                     /locus_tag="IRB70_002101"
     CDS             complement(20173..21189)
                     /gene="cysP"
                     /locus_tag="IRB70_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate/sulfate ABC transporter
                     substrate-binding protein CysP"
                     /protein_id="HBC0632014.1"
                     /translation="MAVNLLKKNSLALVASLLLAGHVQATELLNSSYDVSRELFAALN
                     PPFEQQWAKDNGGDKLTIKQSHAGSSKQALAILQGLKADVVTYNQVTDVQILHDKGKL
                     IPADWQSRLPNNSSPFYSTMGFLVRKGNPKNIHDWNDLVRSDVKLIFPNPKTSGNARY
                     TYLAAWGAADKADGGDKAKTEQFMTQFLKNVEVFDTGGRGATTTFAERGLGDVLISFE
                     SEVNNIRKQYEAQGFEVVIPKTNILAEFPVAWVDKNVQANGTEKAAKAYLNWLYSPQA
                     QTIITDYYYRVNNPEVMDKLKNKFPQTELFRVEDKFGSWPEVMKTHFTSGGELDKLLA
                     AGRN"
     gene            complement(21347..22138)
                     /gene="ucpA"
                     /locus_tag="IRB70_002102"
     CDS             complement(21347..22138)
                     /gene="ucpA"
                     /locus_tag="IRB70_002102"
                     /EC_number="1.-.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416921.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase UcpA"
                     /protein_id="HBC0632015.1"
                     /translation="MGKLTGKTALITGALQGIGEGIARTFARHGANLILLDISPEIEK
                     LADELCGRGHRCTAVVADVRDPASVAAAIKRAKEKEGRIDILVNNAGVCRLGSFLDMS
                     DEDRDFHIDINIKGVWNVTKAVLPEMIARKDGRIVMMSSVTGDMVADPGETAYALTKA
                     AIVGLTKSLAVEYAQSGIRVNAICPGYVRTPMAESIARQSNPEDPESVLTEMAKAIPM
                     RRLADPLEVGELAAFLASDESSYLTGTQNVIDGGSTLPETVSVGI"
     gene            complement(22267..23124)
                     /gene="murR"
                     /locus_tag="IRB70_002103"
     CDS             complement(22267..23124)
                     /gene="murR"
                     /locus_tag="IRB70_002103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MurR"
                     /protein_id="HBC0632016.1"
                     /translation="MLYLTKIRNAESEFTGNEQKIADFLRANVSELKSVSSRKMAKQL
                     GISQSSIVKFAQKLGAQGFTELRMALIGEYSASREKTNATALHLHSSITSDDSLEVIA
                     RKLNREKEQALEQTCALFDYARLQKIIEVISKAPFIQITGLGGSALVGRDLSFKLMKI
                     GYRVACEADTHVQATVSQALKKGDVQIAISYSGSKKEIVLCAEAARKQGATVIAITSL
                     TDSPLRRLAHYTLDTVSGETEWRSSSMSTRTAQNSVTDLLFVGLVQLNDVESLKMIER
                     SSELTQRLK"
     gene            23288..24184
                     /gene="murQ"
                     /locus_tag="IRB70_002104"
     CDS             23288..24184
                     /gene="murQ"
                     /locus_tag="IRB70_002104"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBC0632017.1"
                     /translation="MQLEKMITEGSNAASAEIDRVSTLEMCRIINDEDKTVPLAVERV
                     LPDIAAAIDVIHAQVSGGGRLIYLGAGTSGRLGILDASECPPTYGVKPGLVVGLIAGG
                     EYAIQHAVEGAEDSREGGVNDLKNIGLTAQDVVVGIAASGRTPYVIAGLEYARQLGCR
                     TVGISCNPGSAVSTTAEFAITPVVGAEVVTGSSRMKAGTAQKLVLNMLSTGLMIKSGK
                     VFGNLMVDVVATNEKLHVRQVNIVKNATGCSAEQAEAALVACERNCKTAIVMVLKNLD
                     AAEAKKRLDQHGGFIRQVLDKE"
     gene            24188..25612
                     /gene="murP"
                     /locus_tag="IRB70_002105"
     CDS             24188..25612
                     /gene="murP"
                     /locus_tag="IRB70_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylmuramic acid transporter subunit
                     IIBC"
                     /protein_id="HBC0632018.1"
                     /translation="MAKEISSELLNTILTRVGGPGNIASCGNCMTRLRLGVHDSSLVD
                     PNIKTLEGVKGVILTSDQVQVVFGPGKAHRAAKAMSELLGEAPVQDAAEIAAQNKRQL
                     KAKQTSGVQQFLAKFATIFTPLIPGFIAAGLLLGIATLIATVMHVPADAQGTLPDALN
                     FMKVFSKGLFTFLVILVGYNAAQAFGGTGVNGAIIAALFLLGYNPAATTGYYAGFHDF
                     FGLPIDPRGNIIGVLIAAWACARIEGMVRRFMPDDLDMLLTSLITLLITATLAYLIIM
                     PLGGWLFEGMSWLFMHLNSNPLGCAVLAGLFLIAVVFGVHQGFIPVYLALMDSQGFNS
                     LFPILSMAGAGQVGAALALYWRAQPHSALRSQVRGAIIPGLLGVGEPLIYGVTLPRMK
                     PFVTACLGGAAGGLFIGLIAWWGLPMGLNSAFGPSGLVALPLMTSAQGILPAMAVYAG
                     GILVAWVCGFIFTTLFGCRNVNLD"
     gene            25617..26918
                     /gene="pbp4b"
                     /locus_tag="IRB70_002106"
     CDS             25617..26918
                     /gene="pbp4b"
                     /locus_tag="IRB70_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416925.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin binding protein PBP4B"
                     /protein_id="HBC0632019.1"
                     /translation="MKRTMLCLSLLAVSCSVSAAKYPVLTESSPEKAGFNVERLNQMD
                     RWISQQVDDGYPGVNLLIIKDNQIVYRKAWGAAKKYDGSALMAQPLKATTGTLYDLAS
                     NTKMYATNFALQKLMSEGKLHPDDRIAKYIPGFADSPNDAIKGKNTLRISDLLHHSGG
                     FPADPQYPNKAVAGALYSQDKGQTLEMIKRTPLEYQPGSKHIYSDVDYMLLGFIVESV
                     TGQPLDRYVEESIYRPLGLTHTVFNPLLKGFKPQQIAATELNGNTRDGVIHFPNIRTS
                     TLWGQVHDEKAFYSMGGVSGHAGLFSNTGDIAVLMQTMLNGGGYGDVQLFNAETVKMF
                     TTSSKEDATFGLGWRVNGNATMTPTFGTLASPQTYGHTGWTGTVTVIDPVNHMAIVML
                     SNKPHSPVADPQKNPNMFESGQLPIATYGWVVDQVYAALKQ"
     gene            complement(26976..27875)
                     /gene="yfeX"
                     /locus_tag="IRB70_002107"
     CDS             complement(26976..27875)
                     /gene="yfeX"
                     /locus_tag="IRB70_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311329.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphyrinogen peroxidase"
                     /protein_id="HBC0632020.1"
                     /translation="MSQVQSGILPEHCRAAIWIEANVKGEVDALRAASKTFADKLATF
                     EAKFPDAHLGAVVAFGNNTWRALSGGVGAEELKDFPGYGKGLAPTTQFDVLIHILSLR
                     HDVNFSVAQAAMEAFGDCIEVKEEIHGFRWVEERDLSGFVDGTENPAGEETRREVAVI
                     KDGVDAGGSYVFVQRWEHNLKQLNRMSVHDQEMMIGRTKEANEEIDGDERPETSHLTR
                     VDLKEDGKGLKIVRQSLPYGTASGTHGLYFCAYCARLHNIEQQLLSMFGDTDGKRDAM
                     LRFTKPVTGGYYFAPSLDKLMAL"
     gene            complement(27971..28546)
                     /locus_tag="IRB70_002108"
     CDS             complement(27971..28546)
                     /locus_tag="IRB70_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RpoE-regulated lipoprotein"
                     /protein_id="HBC0632021.1"
                     /translation="MKSLRLMLCAMPLMLTGCSTMSSVNWSAANPWNWFGSSTKVSEQ
                     GVGELTASTPLQEQAIADALDGDYRLRSGMKTANGNVVRFFEVMKGDNVAMVINGDQG
                     TISRIDVLDSDIPADTGVKIGTPFSDLYSKAFGNCQKADSDDNRAVECKAEGSQHISY
                     QFSGEWSGPEGLMPSDDTLKNWKVSKIIWRR"
     gene            complement(28607..29056)
                     /locus_tag="IRB70_002109"
     CDS             complement(28607..29056)
                     /locus_tag="IRB70_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2919 domain-containing protein"
                     /protein_id="HBC0632022.1"
                     /translation="MKSTEFHPVHYDAHGRLRLPLLFWLVLLLQARTWVLFVIAGASR
                     EQGTALLNLFYPDHDNFWLGLIPGIPAVLAFLLSGRRASFPRIWHVLYFLLLLAQVVL
                     LCWQPWLWLNGESVSGIGLALVVADIVALIWLLTNRRLRACFNEEKE"
     gene            complement(29043..29468)
                     /locus_tag="IRB70_002110"
     CDS             complement(29043..29468)
                     /locus_tag="IRB70_002110"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311332.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family acetyltransferase"
                     /protein_id="HBC0632023.1"
                     /translation="MEIRVFRQEDFEEVITLWERCDLLRPWNDPEMDIERKMNHDVSL
                     FLVAEVNGEVVGTVMGGYDGHRGSAYYLGVHPEFRGRGIANALLNRLEKKLIARGCPK
                     IQINVPEDNDMVLGMYERLGYEHADVLSLGKRLIEDEEY"
     gene            29682..30551
                     /gene="amiA"
                     /locus_tag="IRB70_002111"
     CDS             29682..30551
                     /gene="amiA"
                     /locus_tag="IRB70_002111"
                     /EC_number="3.5.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase AmiA"
                     /protein_id="HBC0632024.1"
                     /translation="MSTFKPLKTLTSRRQVLKAGLAALTLSGMSQAIAKDEPLKTSNG
                     HSKPKAKKSGGKRVVVLDPGHGGIDTGAIGRNGSKEKHVVLAIAKNVRSILRNHGIDA
                     RLTRSGDTFIPLYDRVEIAHKHGADLFMSIHADGFTNPKAAGASVFALSNRGASSAMA
                     KYLSERENRADEVAGKKATDKDHLLQQVLFDLVQTDTIKNSLTLGSHILKKIKPVHKL
                     HSRNTEQAAFVVLKSPSVPSVLVETSFITNPEEERLLGTAAFRQKIATAIAEGVISYF
                     HWFDNQKAHSRKR"
     gene            30555..31454
                     /gene="hemF"
                     /locus_tag="IRB70_002112"
     CDS             30555..31454
                     /gene="hemF"
                     /locus_tag="IRB70_002112"
                     /EC_number="1.3.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-dependent coproporphyrinogen oxidase"
                     /protein_id="HBC0632025.1"
                     /translation="MKPDAHLVKQFLLNLQDTICQQLTAVDGAEFVEDSWQREAGGGG
                     RSRVLRNGGVFEQAGVNFSHVHGEAMPASATAHRPELAGRSFEAMGVSLVVHPHNPYV
                     PTSHANVRFFIAEKPGAEPVWWFGGGFDLTPFYGFEDDAIHWHRTARDLCLPFGEDVY
                     PRYKKWCDEYFYLKHRNEQRGIGGLFFDDLNTPDFDHCFAFMQAVGKGYTNAYLPIVE
                     RRKTMAYGERERNFQLYRRGRYVEFNLVWDRGTLFGLQTGGRTESILMSMPPLVRWEY
                     DYQPEAGSPEAALSGFIKVRDWV"
     gene            complement(31460..32512)
                     /gene="eutR"
                     /locus_tag="IRB70_002113"
     CDS             complement(31460..32512)
                     /gene="eutR"
                     /locus_tag="IRB70_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator EutR"
                     /protein_id="HBC0632026.1"
                     /translation="MKKTRTANLHHLYHEPLPENLKLTPKVEVDNVHQRQTTDVYEHA
                     LTITAWQQIYDQLHPGKFHGEFTEILLDDIQVFREYTGLALRQSCLVWPNSFWFGIPA
                     TRGEQGFIGSQCLGSAEIATRPGGTEFELSTPDDYTILGVVLSEDVITRQANFLHNPD
                     RVLHMLRSQSALEVKEQHKAALWGFVQQALATFCENPENLHQPAVRKVLGDNLLMAMG
                     AMLEEAQPMVTAESISHQSYRRLLSRAREYVLENMSEPVTVLDLCNQLHVSRRTLQNA
                     FHAILGIGPNAWLKRIRLNAVRRELISPWSQSMTVKDAAMQWGFWHLGQFATDYQQLF
                     AEKPSLTLHQRMREWG"
     gene            complement(32558..33058)
                     /gene="eutK"
                     /locus_tag="IRB70_002114"
     CDS             complement(32558..33058)
                     /gene="eutK"
                     /locus_tag="IRB70_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311336.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutK"
                     /protein_id="HBC0632027.1"
                     /translation="MINALGLLEVDGMVAAIDAADAMLKAANVRLLSHEVLDPGRLTL
                     VVEGDLAACRAALDAGCAAAMRTGRVISRKEIGRPDDDTQWLVTGFNRQPKQPVKEPD
                     APVIVAESADELLALLTSVRQGMTAGEVAAHFGWPLEKARNALEQLFSAGTLRKRSSR
                     YRLKPH"
     gene            complement(33071..33730)
                     /gene="eutL"
                     /locus_tag="IRB70_002115"
     CDS             complement(33071..33730)
                     /gene="eutL"
                     /locus_tag="IRB70_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization microcompartment
                     protein EutL"
                     /protein_id="HBC0632028.1"
                     /translation="MPALDLIRPSVTAMRVIASVNAEFARELKLPPHIRSLGLISADS
                     DDVTYIAADEATKQAMVEVVYGRSLYAGAAHGPSPTAGEVLIMLGGPNPAEVRAGLDA
                     MVANIENGAAFQWANDAENTAFLAHVVSRTGSYLSSTAGITLGDPMAYLVAPPLEATY
                     GIDAALKSADVQLVTYVPPPSETNYSAAFLTGSQAACKAACNAFTDAVLEIARNPIQR
                     A"
     gene            complement(33740..34627)
                     /gene="eutC"
                     /locus_tag="IRB70_002116"
     CDS             complement(33740..34627)
                     /gene="eutC"
                     /locus_tag="IRB70_002116"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit beta"
                     /protein_id="HBC0632029.1"
                     /translation="MDQKQIEEIVRSVMASMGQAAPAPSEAKCATTTCAAPVTSESCA
                     LDLGSAEAKAWIGVENPHRADVLTELRRSTVARVCTGRAGPRPRTQALLRFLADHSRS
                     KDTVLKEVPEEWVKAQGLLEVRSEISDKNLYLTRPDMGRRLCAEAVEALKAQCVANPD
                     VQVVISDGLSTDAITVNYEEILPPLMAGLKQAGLKVGTPFFVRYGRVKIEDQIGEILG
                     AKVVILLVGERPGLGQSESLSCYAVYSPRMATTVEADRTCISNIHQGGTPPVEAAAVI
                     VDLAKRMLEQKASGINMTR"
     gene            complement(34648..36009)
                     /gene="eutB"
                     /locus_tag="IRB70_002117"
     CDS             complement(34648..36009)
                     /gene="eutB"
                     /locus_tag="IRB70_002117"
                     /EC_number="4.3.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase subunit alpha"
                     /protein_id="HBC0632030.1"
                     /translation="MKLKTTLFGNVYQFKDVKEVLAKANELRSGDVLAGVAAASSQER
                     VAAKQVLSEMTVADIRNNPVIAYEDDCVTRLIQDDVNETAYNQIKNWSISELREYVLS
                     DETSVDDIAFTRKGLTSEVVAAVAKISSNADLIYGAKKMPVIKKANTTIGIPGTFSAR
                     LQPNDTRDDVQSIAAQIYEGLSFGVGDAVIGVNPVTDDVENLSRVLDTIYGVIDKFNI
                     PTQGCVLAHVTTQIEAIRRGAPGGLIFQSICGSEKGLKEFGVELAMLDEARAVGAEFN
                     RIAGENCLYFETGQGSALSAGANFGADQVTMEARNYGLARHYDPFIVNTVVGFIGPEY
                     LYNDRQIIRAGLEDHFMGKLSGISMGCDCCYTNHADADQNLNENLMILLATAGCNYIM
                     GMPLGDDIMLNYQTTAFHDTATVRQLLNLRPSPEFERWLESMGIMANGRLTKRAGDPS
                     LFF"
     gene            complement(36021..37424)
                     /gene="eutA"
                     /locus_tag="IRB70_002118"
     CDS             complement(36021..37424)
                     /gene="eutA"
                     /locus_tag="IRB70_002118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine ammonia-lyase reactivating factor
                     EutA"
                     /protein_id="HBC0632031.1"
                     /translation="MNTRQLLSVGIDIGTTTTQVIFSHLELVNRAAVSQVPRYEFIKR
                     EISWQSPVFFTPVDKQGGLKEAELKTLILEQYQAAGIAPESVDSGAIIITGESAKNRN
                     ARPAVMTLSRSLGDFVVASAGPHLESVIAGHGAGAQTLSEQRLCRVLNIDIGGGTANY
                     ALFDAGKISGTACLNVGGRLLETDSQGRVVYAHKPGQMIVDECFGAGTDARSLTGAQL
                     VQVTRRMAELIVEVIDGTLSPLAQALMQTGLLPAGVTPEIITLSGGVGECYRHQPADP
                     FCFADIGPLLATALHDHPRLREMNVQFPAQTVRATVIGAGAHTLSLSGSTIWLEGVQL
                     PLRNLPVAIPIDEKDLVSAWQQALIQLDLDPKTDAYVLALPASLPVRYAAVLTVINAL
                     VDFVARFPNPHPLLVVAGQDFGKALGMLLRPQLQQLPLAVIDEVIVRAGDYIDIGTPL
                     FGGSVVPVTVKSLAFPS"
     gene            complement(37421..38647)
                     /gene="eutH"
                     /locus_tag="IRB70_002119"
     CDS             complement(37421..38647)
                     /gene="eutH"
                     /locus_tag="IRB70_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutH"
                     /protein_id="HBC0632032.1"
                     /translation="MGINEIIMYIMMFFMLIAAVDRILSQFGGSARFLGKFGKSIEGS
                     GGQFEEGFMAMGALGLAMVGMTALAPVLAHVLGPVIIPVYEMLGANPSMFAGTLLACD
                     MGGFFLAKELAGGDVAAWLYSGLILGSMMGPTIVFSIPVALGIIEPSDRRYLALGVLA
                     GIVTIPIGCIAGGLVAMYSGVQINGQPVEFTFALILMNMIPVLIVAVLVALGLKFIPE
                     KMINGFQIFAKFLVALITLGLAAAVVKFLLGWELIPGLDPIFMAPGDKPGEVMRAIEV
                     IGSISCVLLGAYPMVLLLTRWFEKPLMSVGKVLNMNNIAAAGMVATLANNIPMFGMMK
                     QMDTRGKVINCAFAVSAAFALGDHLGFAAANMNAMIFPMIVGKLIGGVTAIGVAMMLV
                     PKEDASAAKTEAEAQS"
     gene            complement(38764..39951)
                     /gene="eutG"
                     /locus_tag="IRB70_002120"
     CDS             complement(38764..39951)
                     /gene="eutG"
                     /locus_tag="IRB70_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization ethanol dehydrogenase
                     EutG"
                     /protein_id="HBC0632033.1"
                     /translation="MQNELQTALFQAFDTLNLQRVKTFSVPPVTLCGPGAVSSCGQQA
                     QTRGLKHLFVMADSFLHQAGMTAGLTRSLAVKGIAMTLWPCPVGEPCITDVCAAVAQL
                     RESGCDGVIAFGGGSVLDAAKAVALLVTNPDSTLAEMSETSVLQPRLPLIAIPTTAGT
                     GSETTNVTVIIDAVSGRKQVLAHASLMPDVAILDAALTEGVPSHVTAMTGIDALTHAI
                     EAYSALNATPFTDSLAIGAIAMIGKSLPKAVGYGHDLAARESMLLASCMAGMAFSSAG
                     LGLCHAMAHQPGAALHIPHGLANAMLLPTVMEFNRMVCRDRFSQIGRALRTKKSDDRD
                     AINAVSELIAEVGIGKRLGDVGATSAHYGAWAQAALEDICLRSNPRTASLEQIVGLYA
                     AAQ"
     gene            complement(39941..40777)
                     /gene="eutJ"
                     /locus_tag="IRB70_002121"
     CDS             complement(39941..40777)
                     /gene="eutJ"
                     /locus_tag="IRB70_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HBC0632034.1"
                     /translation="MAHDEQWLTPRLQTAATLCNQTPAATESPLWLGVDLGTCDVVSM
                     VVDRDGLPVAVCLDWADVVRDGIVWDFFGAVTIVRRHLDTLEQQFGRRFSHAATSFPP
                     GTDPRISINVLESAGLEVSHVLDEPTAVADLLQLDNAGVVDIGGGTTGIAIVKKGKVT
                     YSADEATGGHHISLTLAGNRRISLEEAEQYKRGHGEEIWPAVKPVYEKMADIVARHIE
                     GQGITDLWLAGGSCMQPGVAELFRKQFPALQVHLPQHSLFMTPLAIASSGREKAEGLY
                     AK"
     gene            complement(40788..>40897)
                     /locus_tag="IRB70_002122"
     CDS             complement(40788..>40897)
                     /locus_tag="IRB70_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aldehyde dehydrogenase"
                     /protein_id="HBC0632035.1"
                     /translation="WTTMTITTPTGEGVTSARTFVRLRRCVLVDAFRIV"
BASE COUNT         9764 a        11334 c        10287 g         9512 t
ORIGIN      
        1 tcacccacca cttcgggtcg ttagctcagt tggtagagca gttgactttt aatcaattgg
       61 tcgcaggttc gaatcctgca cgacccacca atgtaaaaaa gcgccctaaa ggcgcttttt
      121 tgctatctgc aatttgcgaa attgcctgat gcgcttcgct tatcagacca actatgtccg
      181 gcagttcccg tgcctctcat ctactgcgcc aacgccgcca gcagtttaac cagcgcgggc
      241 gtcacctgct gcgtttcata aacaatatat aagtctgccg ggatgcgttc tttgagcgga
      301 cggaatatga caccgggcca gttcatctgc gcgtagctgt ccgctatcaa tgtgatacca
      361 atacccatac tgaccatggc gagtaccgtt tgcggttcat taacttcgcg aataacaacc
      421 ggtgaaaatc ccacctgctg gcaaactcgc tgcaaaaaat cccagtcagt gtacacgggc
      481 ggcattgtaa cgaaatactc gtcacgtagc gcttccagcg ggacggtgga aaatgatgag
      541 agatgatgct cttcaggcat cgccaccaga aacgccgatt catgcaaccg taagctggta
      601 aaaccagtcg gtggttctgt cgccattcgc cagatcccgg catcaagttc gcggcgttcc
      661 agcaaggcca tttgcatcgc gggcatcttt tcgcgaaaca gaacttcaac gttaggattt
      721 tctctaagga atcgccgcat aaccgggcgc atccgtcccc acattgccgt tcccacaacc
      781 ccgagttcaa tccgccctgc ttctccccga cctatttgtt caacccgagc caatacatta
      841 tttgcattca ccaacaatcg acgcgattct tccatcaaga ttttgcccgc gtgtgtcagt
      901 acgacgctgc gtgaatggcg aataaaaagc tgcgtgccaa gttgattttc cagctcttta
      961 atatgaatac tgagcggagg ctgagacata tttaaacgcg ctgctgcgcg accaaaatgc
     1021 aactcttccg ctacggcaag aaaataacgg agcaacttaa gatctgttct atatacgcgt
     1081 tccataatta agtgctccat ataaaaaaat atatcgtatt aaattatcat ggcataaagt
     1141 atttcaccac cagatatccg acatacataa acacgatgga taatataccc ggcaatacat
     1201 ttggaacagg aataggtaat cgcacgattg taaacaaagc accaatgcca aaaccaacgc
     1261 cagaagaaaa taaaatatct ttcactaatt aacctttatc ataaaagcag ccccaaggaa
     1321 cagagctgcg aatcctttta atgtgtaact gaacgatgcg ttatcttttc agggtcatgg
     1381 ttatatttaa acccaaagaa aaatatcact gcgaggaaaa gagcataccc tgcaaacatc
     1441 agccaaatgg tatgccaatc ttttacgcca tccaccgaga agtaatccac tgccataccg
     1501 ctcagaatcg agccaaccca tgcgccgacg ccatttacca tcgtcataaa aaggccctgg
     1561 gcgctggcac gaatgctgga atcaacttcc tgttcgacaa agaccgaacc agaaatattg
     1621 aagaaatcga atgcacaacc gtaaacaatc atcgacagca gcaacaaaat aaacccggtt
     1681 ggtgatgggt cgccataggc aaagaagcca aagcgcagcg tccacgccac catactcatc
     1741 agcatgacgg ttttaatacc gaaacgcttc aaaaagaacg gtatcgtcag aatgaaaccg
     1801 acttcagcca tctgtgaaac tgacagtaaa atggacgggt atttcaccac gaagctatca
     1861 gcaaactcag gattacgggc gaaatcatgc aggaacgggt tgccaaaaac gttggtaatt
     1921 tgcagcaccg cacccagcat catggcgaag aggaaaaaga tagccatgcg tggattttta
     1981 aacagcacga aggcatccag gcccagcttg ctggcaagcg atgtagtcgc ttttttctcc
     2041 gcaaccggaa tcttcggcaa agtcagcgca taagccgaca gcagcaatga cgcaccggac
     2101 gcgatataca gttgcagact actcaattcc agatgcagca ggcttactgc ccacatggcg
     2161 acaatgaacc ccaccgtacc aaaaacgcga atgggcggga aagcggtcac cgggtcaagc
     2221 cctgcctggg caagacagga ataagagacg ctgttcgata acgcaatagt cggcataaac
     2281 gccatcgcat tgactaacat cacccaaaac atcatatccg gatcagttac ggatgccgca
     2341 taaaaaagta cgcccgcaca caccaggtga cacagcatgt atgcacgttc tgcacgcagc
     2401 catttgtctg cgatgatccc cattatacca ggcataataa tcgcggcgat ccctttggaa
     2461 ctgtaaacca tgccaacatt agcgccggtg aaatgaaggg tattaatcat gtaagaaccg
     2521 agggtaacca gccagctccc ccagataaaa tattgcaaaa aggacattac ctttaagcgc
     2581 aaagcgatgc tcataatcgt ttccttgtcg catcatatgg cctcacccgc gaggccgttt
     2641 cttattgttt ttctcaggca attttgcgca gaaagccaca aataaggttg atgaagttct
     2701 gcttagagag ctccgcagcc gccagcgttt gcgcatgtga caatttcaca tcgcttaaac
     2761 cttccgccat attggtaatc gcagagaccg caacgacttt aagttcgcaa tggcgagcag
     2821 aaataacctc aggcaccaca gacataccaa caacatcccc accaataatt tgcatcatgc
     2881 gaatttccgc cgcagtctcg aaattcggac ccggatacga gacgaacacg ccctccgtca
     2941 gagggaaccc ctcttctttc gccacttttt gtaacagtgc gcggtattcc gcatcgtagg
     3001 cattcgccag cgagaagaag cgctcaccaa aacgttcatc attaagaccc accatcggcg
     3061 ttcccggcat ggtgttgata tgatctttca atgcgaccag actgccggcc cccacttcag
     3121 gacgcagtga gccagccgca ttggtgctga acagcaactc gcagcccagc aacttaaagg
     3181 tacggattgc atccgtcatg atggtcatcc cacgaccttc gtagaaatgt ccgcgacctt
     3241 tcatgcacac cactggcacc ccctggagat aacccagcac cagctcaccc gcatggccat
     3301 gtacggtact taccgggaac ccaggcagct tttcgtagga aattgcgacc gcgttctcaa
     3361 tctgatcggc cagcgcgccc agcccggaac ctaaaataaa ggccactcgt ggcgtgaaat
     3421 caggtttata agtcttgata atatctacgc aatacagtgg gttatgagaa aactgagcct
     3481 gatacatata tatccttttt ttgtagggtg gaatctaacg cctttttata acgagattgc
     3541 cctaactcat accaatacac ttttttcatg tatccgatag ttattcgata tcgatatatt
     3601 tatatttttt cactattaat agacggaaaa aactgtattg gtactctcct ttccattgca
     3661 ttaacaatat gccgctttta atcaaccctt ttattaagca atcaactaat aacgatcggc
     3721 atagggaatt atgctatgaa aaaacatctt tttactctga cactctcttc tgtattggcg
     3781 ataccagcag tatcccatgc agaatttaaa ggcggttttg ctgatatagg tattcattat
     3841 cttgactgga ctagcagaac cactgagaaa tcgtcgacca aatcacacaa agatgatttt
     3901 ggatatctgg aactggaagg cggcgctaac tttagttggg gagaaatgta cgggttcttc
     3961 gactgggaaa acttttataa taatcgtcat gataaaccgg gtagcgagca gcgttacaca
     4021 tttaaaaata ccaaccgtat ttacctgggt gacaccggat ttaatctcta cttgcatgcg
     4081 tatggcacct acggttctgc gaatcgtgtg aatttccatg acgatatgtt cctttacggg
     4141 atcggctaca atttcaccgg cagcggttgg tggttcaaac cgttctttgc aaaacgctat
     4201 acagaccaaa cctattatac cggcgataac ggttatgtcg ccggttgggt tgcaggttac
     4261 agctttatgc tgggcagtga gaaattcacc ctcaccaact ggaacgagta cgagtttgat
     4321 cgtgatgcca cctacgcggc aggtaatggc ggcaaagaag gtctgaacgg tgccgtcgca
     4381 ctttggtgga atgcaacttc acacatcacc acagggattc agtatcgtta tgcggatgac
     4441 aaactgggcg aagattttta ccaggatgca ataatctact ccatcaaatt taatttctga
     4501 ttgattactg ccggggctcc cggcagtatg aatagctcta tatctgatac agcggatccc
     4561 cttcccgccc agccattagc gcacggccct ggcctcgtac cacgtcccat aacgcttgtg
     4621 cggcggtgga aagtgaacgg ttcttcctgc gcaccagcat caactggcgt tccaccaccg
     4681 gcgtaatgcg ctttaccacc agcgggctac cttcaggcaa tggtagcgcc agtgcgggaa
     4741 gaatactgat gccgatgcct gcggctacca tcgggaacag cgtcgccgga tgtccaatct
     4801 cctgcacaat attcgcctga ataccattgc gcgccagagc tgcgtcaatc agcggtcggc
     4861 tgcctgacgc gtaatcctgc aacaccaatt tcgccccctg taatgcctgc cagggtacat
     4921 aatcttccgc ggccaaagcg ctatcgcgat ggcaaagcag aaagaaaggc tcggaaagaa
     4981 tcgcttcaca ttgcagatcg cccactgggc ctggatcgat gacgatgcca aagtcgacat
     5041 ctccctggcg aatactttcc atcacccact gctgcggacg atcgtgcagg ataaactgaa
     5101 tatctggata gcggcgatgg ctttcagcaa tgcattgcgg aataagatgc gcggaaatgg
     5161 tctggctggc agcgacccga acttttccgc tcagttgttg ccccatacgc ccggtatcgc
     5221 gcaacgtgct gttaagttca tccagcagtc gctcaagacg caaagccaac tgctgccctg
     5281 catctgtaag caccacttca cgcgtggttc tgtccagcag gcgaacacca gtatgatttt
     5341 ccagctcctt cacactgtga ctcactgccg actggctcag gccgatacgc tctcctgcac
     5401 gactaaaact tttctcctgc gctactgtga cgaaaacctt taattgtttt aaagaataat
     5461 tcatctgttt tcttcatgaa tggatgcaat aaatcaattt tatttctcaa actggaagaa
     5521 gcacaataga accatcgatc atctggagtc tttatgaaac tttttcgtat cctcgatcct
     5581 ttcaccttaa ccctgatcac ggtggtgttg ctggcctctt tctttccggc caggggtgat
     5641 ttcgttccct tctttgaaaa tctgactacc gcagccattg ctctgctgtt ctttatgcac
     5701 ggcgcgaagt tatcgcgaga ggccattatt gcaggcggtg gtcattggcg actgcatttg
     5761 tgggtaatgt gcagcacctt cgtgctgttc ccaattttgg gcgtgctgtt tgcctggtgg
     5821 aaaccggtaa atgtcgaccc gatgctctat tccggttttc tctacttgtg cattcttcct
     5881 gctaccgtgc agtctgcaat cgccttcacg tcaatggcgg gcggtaacgt cgcggcggcg
     5941 gtttgttctg cgtcagcatc cagcctgctg gggattttcc tttcaccatt gctggttggt
     6001 ctggtgatga atgttcacgg tgcagggggc agccttgagc aggtcggtaa aattatgctg
     6061 caactgttgc tgccatttgt gttggggcat ctttcccggc cgtggattgg tgactgggtg
     6121 tcgcgcaata aaaaatggat tgcgaaaact gaccagacgt ccattctgtt ggtggtttat
     6181 acagcgttca gcgaagccgt cgttaatggt atctggcata aagttggctg gggatcattg
     6241 ctgtttatcg tggtggtcag ctgcgttctt ctggctattg tgattgtgat taacgtcttt
     6301 atggcacgcc gactgggctt caataaggca gatgaaatta ctatcgtctt ttgtggttcg
     6361 aaaaagagtc tggcaaatgg catcccgatg gcaaacattc tgttccccac atcggtgatc
     6421 ggtatgatgg tgctgcctct gatgattttc catcagatcc aattgatggt ctgtgcggtg
     6481 ctggcgcgtc gatacaaacg ccagaccgaa cagttacagg cgcagcagga aagcagcgcc
     6541 aataaagctt aaagcggacg cttcaggggc tggaccagtt gcgtcagccc ctcagtttta
     6601 atcagcagcg tgatttgcat tagctcaccg agcttccctg ccgggaactc atctttgcgg
     6661 gcaaaccaca gcagatactc ctccggcagg tcgattaagc gacgcccttt gtatttgcca
     6721 aacggcatta tcgtattggc tatttcaatc agctgctctt tttccatctc agctacccag
     6781 caaacgcagc atttccgctt cgtcgatgac ttcaatgccc agttcctgcg ccttcgccag
     6841 tttagatcct gcagcttcac ccgctatcac cagatcggtt ttcttcgaca cgctgcccgc
     6901 gactttcgcg cccagttcga ccagtcgagc tttagcgtca tcacgcgaca tctggcttaa
     6961 gctgcccgta agcaccacgg ttttaccagc aaacgggctg tcaatctctt ccgcgttaat
     7021 caccaccggc gcaggccagt gaacgccttc cgccaacagc tcgctgatga cattgcggtt
     7081 gctttcttcg gcaaagaagt tgtgaacgtg ggaggcaacg acaatgccaa catcaggcac
     7141 cttttgcagc tcttcaatcg aagcggcttc cagcgcttcc agcgtgccga aatatgccgc
     7201 cagacctgct gcggtggcct cgccgacttc acggatgcca agtgcataga ggaagcgagc
     7261 aaaggtggtt tctttcgctt tttccagcgc gttaaccacg ttttgtgccg attttggccc
     7321 catacgctcc agtccggtca gtttgcctgc ggtgagtttg aacagatccg ccggagtgtg
     7381 gacatattct ttttcaacca gctgatcgat gattttgtcg cccattccgt caacatccat
     7441 cgcacggcgg gaaacaaagt gtttcagcga ctctttacgc tgcgcaccgc aaatcaggcc
     7501 accggtacag cgggcaaccg cttcaccttc cacacgctcg acgtcagaac cacataccgg
     7561 acaatgcgtc gggaatacaa cctcacgggt atcttccggg cgttcagaaa gcacgacgtt
     7621 aaccacctgc gggatcacgt cgccagcgcg gcgaatcacc actttatcgc caatgcgtaa
     7681 accaagacgt tcgatttcat ccgcattgtg taaggttgcg ttactcacca gcacgccagc
     7741 aacatggaca ggttccagac gcgcaacagg cgtaatcgcg ccagtacgcc caacctgaaa
     7801 ctcgacgtca cgcacaaagg tcatctgttc ctgcgccgga aatttaaacg ctaccgccca
     7861 gcgcggggca cgcgcgacaa agccaagctg ctcctgctgt gccagtgagt tgactttaat
     7921 caccacgccg tcgatatcaa agcccagcgt cgggcggtct tcttccactt tgtgatagaa
     7981 cgccagcact tcttccgccg attcacaaag cgttacccga tcgctgaccg gcaaccccca
     8041 ctttttaaat tgcagtaagc ggccaagatg agtatccggc agctcgccac cttccagaac
     8101 accaacgccg tagcagaaaa aagtgagcgg tcgcttcgct gtaatacgcg gatcaagctg
     8161 acgcagtgaa ccagctgccg cattacgtgg gttagcaaac actttcccgc ccgtgcgtcg
     8221 cgcatcttcg ttaatctttt cgaaccccgc ctgcggcagg aacacttcac cacgcacttc
     8281 cagacgcgcc gggatattct ctccgtgtag cttcagcgga atggcgcgaa tagtacgcac
     8341 attagacgtg atatcttccc cggtggtgcc atcgccacgg gtcgcggcac tgactaaaac
     8401 accattttca tacagaatac tgactgcaag accatccagc ttcagctcac agcaccaggt
     8461 gactttctcg ttgcttttca gacggtcctg cactcgtttg ttgaaggcaa gaaagctttc
     8521 ttcatcaaaa acgttatcca gcgacagcat tggcacttca tggcggatct ggctgaaagc
     8581 cgccagcggc gcagcaccta cacgttgggt aggcgaatca ggcgtaatca gttctggatg
     8641 tttggtttcc agctcgcgca gttcgcgcat cagcctgtcg tattccgcgt cgggaatttc
     8701 cggcgcatcc atcacatgat aaagatattc atgatggcga agcgtcgttc gcagttctgt
     8761 cagttgttgt tcgattgatt ccatatcgca ccatcaatgc taaaaacccc cgacaagcgg
     8821 gggttcgaaa aggagttaat ttgccttaag tgtatcaggc gttggcgtct ttgacttcgc
     8881 ggatgatgtc ctggtactcg cgcaatttct gcggagtcat catacggcgc tgatcgtcaa
     8941 gcactacacc gcccacttca tcggcaatat gctgcgcaga ttgcagcatt agcttgaagt
     9001 tctgcagctc gtcaccgtaa gacggtacct gcataaagat agtgacaccc ggagtagtga
     9061 aatccttcat ttcaggatca aaggttcccg gtttcaccat attcgccagg ctaaataacg
     9121 ccgggccgct gccatccggg ctaagatgac gatggtaaat attcatatcg ccaaaaatga
     9181 agcccgcttg ttgaatgctg ttaagaagca gttcaccgtt tagctcgcta ccgtgatgcg
     9241 ccgcgacgtt catgataatc accgcttctt tgcgcttcgg tttatccata actggagccg
     9301 gttccgctac aggctcaggc tgtggtgccg ctacaggctc tgcaggctgg aaagcctgtt
     9361 gtgccggttg cggtgctgaa tgcactggct gcggcgctga tgcgacctgt ggcgaaactg
     9421 gctgctgcaa cggctgttca ggctgcggct gataggcagg ctgctgcacg ggttgctgca
     9481 ccggctgcgc tggacgcgga gcatgttgcg gcggtacctg agcttcaggc ggctgctgga
     9541 ccggttgacg cggctgcgca gacgcataag gcggttggta ctggtgttgc ggcgacggac
     9601 gagcagcctc atgctcctgg gcgttagccg gggcatgatt cacgcggtga actcgaacct
     9661 caccaacgcc ctcatcatct tcgacatcct cgtcataaga atcgtcgtca cgttttgact
     9721 tcattcgttt taatggccga tcgcggaaca tagaagatcg ttctttacgg ctggtccaga
     9781 aaccatgtac cagtaaagcg attatggcga tcgcgccaac aatgattaat atcagacgca
     9841 aatcctgcat cattatattc tctgttgttc taacaccttg ccaccacggc aaacatttac
     9901 tcactaagag tatttgccga ttacctcaag tgcaagtgca ctattaactt tcacagcaca
     9961 aagatagatg aaatcgtgct ttttgctgtt ttttcgaaca tatcctaact gtccattgcg
    10021 caattacccg gtaaaatacg cagaattttc ctgggattgg tcaaaaggag ctcatcctga
    10081 ttatggtttc atcattcaca tctgccccac gcagcggttt ttactatttt gcgcaaggct
    10141 ggaagctcgt ctcgcaacct gggattcggc gtttcgttat tttaccgctg ctggtcaata
    10201 ttttgttgat ggggggcgca ttctggtggc tatttacgca gctcgatgtc tggatcccga
    10261 cgctcatgag ttatgttccg gactggttac aatggctgag ctatctgttg tggcctctgg
    10321 ctgtcatctc tgtgctgtta gtgtttggct atttcttctc aacgattgct aactggattg
    10381 ccgctccgtt caatggttta ttggctgaac aactggaagc acgattgact ggcgctacac
    10441 cgccagatac cgggattttc ggtatcatga aagatgtgcc gcgaatcatg aaacgcgaat
    10501 ggcaaaaatt tgcctggtat ctgccgcgcg caattgtatt gctaattctt tacttcatcc
    10561 ctggtattgg gcaaaccgtc gcgccggtac tatggttcct gtttagcgcc tggatgttag
    10621 ccatccagta ttgcgattac cccttcgata accacaaagt gccgtttaaa gagatgcgca
    10681 ccgccctgcg cacacgcaaa atcaccaata tgcagtttgg tgctttaacc agcctgttta
    10741 cgatgatccc gttgcttaat ctgttcatca tgcccgttgc cgtttgtggt gcgacggcga
    10801 tgtgggtcga ttgctatcgc gataaacacg cgatgtggcg gtaacaatct accggttatt
    10861 ttgtaaaccg cttgtgtgaa acaggggtgg cttatgccgc cccttattcc atcttgcatg
    10921 tcattatttc ccttctgcat atagatatgc taaatcctta cttccgcata ttctctgagc
    10981 gggtatgcta cctgttgtat cccaatttca tacagttaag gacaggccat gagtaagatt
    11041 tttgaagata actcgctgac tatcggtcac acgccgctgg ttcgcctgaa tcgcatcggt
    11101 aacggacgca ttctggcgaa ggtggaatct cgtaacccca gcttcagcgt taagtgccgt
    11161 atcggtgcca acatgatttg ggatgccgaa aagcgcggcg tgctgaaacc aggcgttgaa
    11221 ctggttgaac caaccagcgg taataccggg attgcactgg cctatgtcgc tgccgctcgc
    11281 ggttacaaac ttaccctgac catgccagaa accatgagta ttgaacgccg caagctgctg
    11341 aaagcgttag gtgcaaacct ggtgctgacc gaaggtgcta aaggcatgaa aggcgcaatc
    11401 caaaaagcag aagaaattgt cgccagcaat ccagagaaat acctgctgct gcaacaattc
    11461 agcaatccgg caaaccctga aattcacgaa aaaaccaccg gtccggagat ctgggaagat
    11521 accgacggtc aggttgatgt atttattgct ggcgttggga ctggcggtac gctgactggc
    11581 gtcagccgct acattaaagg caccaaaggc aagaccgatc ttatctctgt cgccgttgag
    11641 ccaaccgatt ctccagttat cgcccaggcg ctggcaggtg aagagattaa acctggcccg
    11701 cataaaattc agggtattgg cgctggtttt atcccggcta acctcgatct caagctggtc
    11761 gacaaagtca ttggcatcac caatgaagaa gccatttcta ccgcacgtcg tctgatggaa
    11821 gaagaaggta ttcttgctgg tatctcttct ggagcagctg ttgccgcggc gttgaaacta
    11881 caagaagatg aaagctttac caacaagaat attgtggtta ttctaccatc atcgggtgag
    11941 cgttatttaa gcaccgcatt gtttgccgat ctcttcactg agaaagaact gcaacagtaa
    12001 tgccagcttg ttaaaaatgc gtaaaaaagc accttttcag gtgctttttt gtggcctgct
    12061 tcaaactttc gcccctcctg gcattgattc agcctgtcgg aactggtatt taaccagact
    12121 aattattttg atgcgcgaaa ttaatcgtta caggaaaagc caaagctgaa tcgattttat
    12181 gatttggttc aattcttcct ttagcggcat aatgtttaat gacgtacgaa acgtcagcgg
    12241 tcaacacccg ccagcaatgg actgtattgc gctcttcgtg cgtcgcgtct gttaaaaact
    12301 ggcgctaaca atacaggcta aagtcgaacc gccaggctag actttagttc cacaacacta
    12361 aacctataag ttggggaaat acaatgttcc agcaagaagt taccattacc gctccgaacg
    12421 gtctgcacac ccgccctgct gcccagtttg taaaagaagc taagggcttc acttctgaaa
    12481 ttactgtgac ttccaacggc aaaagcgcca gcgcgaaaag cctgtttaaa ctgcagactc
    12541 tgggcctgac tcaaggtacc gttgtgacta tctccgcaga aggcgaagac gagcagaaag
    12601 cggttgaaca tctggttaaa ctgatggcgg aactcgagta atttcccggg ttcttttaaa
    12661 aatcagtcac aagtaaggta gggttatgat ttcaggcatt ttagcatccc cgggtatcgc
    12721 tttcggtaaa gctctgcttc tgaaagaaga cgaaattgtc attgaccgga aaaaaatttc
    12781 tgccgaccag gttgatcagg aagttgaacg ttttctgagc ggtcgtgcca aggcatcagc
    12841 ccagctggaa acgatcaaaa cgaaagctgg tgaaacgttc ggtgaagaaa aagaagccat
    12901 ctttgaaggg catattatgc tgctcgaaga tgaggagctg gagcaggaaa tcatagccct
    12961 gattaaagat aagcacatga cagctgacgc agctgctcat gaagttatcg aaggtcaggc
    13021 ttctgccctg gaagagctgg atgatgaata cctgaaagaa cgtgcggctg acgtacgtga
    13081 tatcggtaag cgcctgctgc gcaacatcct gggcctgaag attatcgacc tgagcgccat
    13141 tcaggatgaa gtcattctgg ttgccgctga cctgacgccg tccgaaaccg cacagctgaa
    13201 cctgaagaag gtgctgggtt tcatcaccga cgcgggtggc cgtacttccc acacctctat
    13261 catggcgcgt tctctggaac tgcctgctat cgtgggtacc ggtagcgtca cctctcaggt
    13321 gaaaaatgac gactatctga ttctggatgc cgtaaataat caggtttacg tcaatccaac
    13381 caacgaagtt attgataaaa tgcgcgctgt tcaggagcaa gtggcttctg aaaaagcaga
    13441 gcttgctaaa ctgaaagatc tgccagctat tacgctggac ggtcaccagg tagaagtgtg
    13501 cgctaacatt ggtacggttc gtgacgttga aggtgcagag cgtaacggcg ctgaaggcgt
    13561 tggtctgtat cgtactgagt tcctgttcat ggaccgcgac gcgctgccca ctgaagaaga
    13621 acagtttgct gcttacaaag cagtggctga agcgtgtggc tcgcaggcgg ttatcgttcg
    13681 taccatggac atcggcggcg acaaagagct gccatacatg aacttcccga aagaagagaa
    13741 cccgttcctc ggctggcgcg ctatccgtat cgcaatggat cgtaaagaga tcctgcgcga
    13801 tcagctccgc gctatcctgc gtgcctcggc tttcggtaaa ttgcgcatta tgttcccgat
    13861 gatcatctct gttgaagaag tgcgtgcact gcgcaaagag atcgaaatct acaaacagga
    13921 actgcgcgac gaaggtaaag cgtttgacga gtcaattgaa atcggcgtaa tggtggaaac
    13981 accggctgcc gcaacaattg cacgtcattt agccaaagaa gttgatttct ttagtatcgg
    14041 caccaatgat ttaacgcagt acactctggc agttgaccgt ggtaatgata tgatttcaca
    14101 cctttaccag ccaatgtcac cgtccgtgct gaacttgatc aagcaagtta ttgatgcttc
    14161 tcatgctgaa ggcaaatgga ctggcatgtg tggtgagctt gctggcgatg aacgtgctac
    14221 acttctgttg ctggggatgg gtctggacga attctctatg agcgccattt ctatcccgcg
    14281 cattaagaag attatccgta acacgaactt cgaagatgcg aaggtgttag cagagcaggc
    14341 tcttgctcaa ccgacaacgg acgagttaat gacgctggtt aacaagttca ttgaagaaaa
    14401 aacaatctgc taatccacga gatgcggccc aatttactgc ttaggagaag atcatgggtt
    14461 tgttcgataa actgaaatct ctggtttccg acgacaagaa ggataccgga actattgaga
    14521 tcattgctcc gctctctggc gagatcgtca atatcgaaga cgtgccggat gtcgtttttg
    14581 cggaaaaaat cgttggtgat ggcattgcta tcaaaccaac gggtaacaaa atggtcgcgc
    14641 ctgtagacgg caccattggt aaaatctttg aaaccaacca cgcgttctct atcgaatctg
    14701 atagcggcgt tgaattgttc gtccacttcg gtatcgacac cgttgaactg aaaggcgaag
    14761 gcttcaagcg tattgctgaa gaaggtcagc gcgtgaaagt tggcgatacc gtgattgaat
    14821 tcgatctgcc gctgctggaa gagaaagcca agtctaccct gactccggtt gttatctcca
    14881 acatggacga aatcaaagaa ctgatcaaac tgtccggtag cgtaaccgtg ggtgaaaccc
    14941 cggttatccg catcaagaag taattcttgc cgcagtgaaa aatggcgccc atcggcgcca
    15001 tttttttatg cttcagccag aggcggcaaa atcaattcat cgctctcatg ctgctgggta
    15061 tagcgcatca cttccagtac gcgcaacccc gcgcggtgca ccgcatcggt taacgcctcc
    15121 cctttcagca aaccactgat aagctgagca caaaacaggt cgccagtccc tttcaggtca
    15181 gttttaaccc gtgaatggga aatgacattc acgctgtcgg cactgaccac caccacctgc
    15241 atctcctgat tttcttcatt accggaggcg ctggtaatca ccacccattt taatgtgtct
    15301 gaaagcagac tttttgcggc agcaatggca ctgtcgagat cgcggcaatt tttaccggtc
    15361 aggatttcca gctcaaagat attgggggta attccctgcg ccagcggcag taaatattgt
    15421 cgatacgctt cgggaaggtc aggtttgaca taaattccgc tatcaatatc gccgatcacc
    15481 ggatcgacca taatcaataa gtcaggatgg tctttgcgta gcgcagtcag ccactcggca
    15541 aggattttga tttgcgatgc cgttcccata tagcccgtgg ttacagcacg aagttggcgc
    15601 agcgcatcac gctcctgaag cgcacgcaaa taaccgctaa accattcatc cggaatcgca
    15661 ccaccgtaga aagtgtcata atgcggcgta ttgctcagca ataccgtcgg cacggcaaag
    15721 acattcaggc cgttctgttt gatagcaggc accgcaatgc tgttgcccac gctgccgtac
    15781 actacctgcg actgcacggc gacgatatcc gcctgcagtg ccctgctctt atcgttaaac
    15841 aacaacaaac tactcattta attttttctc cttgccgatg atcctcatcg tattccagcc
    15901 gaaactttac ctgattctgg cagtcaaatc ggctattaca aaacaaggat aaggtaattc
    15961 agtgaagaaa atcatttgtc tggtcgttac gctgctaatg acactccccg cttatgcgaa
    16021 gttaacggcc catgaagaag cccgtatcaa cgctatgctg gagggattag cacagaaaaa
    16081 ggatttaata tttgtgcgta acggtgatga acatacctgc gatgaagcgg tttctcatct
    16141 gcgactgaag ctgggcaata cccgtaatcg cattgataca gccgagcagt ttattgacaa
    16201 ggtggcctcg tcgtcatcga ttaccgggaa gccgtatatc gtgaagatgc ccggtaagag
    16261 cgatgagaac gcacagcctt ttttacatgc gttaattgcg cagacggata aaacggtgcc
    16321 tgcgcaataa tcttaaatcc ccgccccctg gctaaaatgc tcttccccaa acaccccggt
    16381 agaaaggtag cgatcgccac gatcgcagat gatcgccacc accaccgcgc cagggttagc
    16441 ttttgccact cgcagtgcac cagcaaccgc gccgccggag ctaacgccac agaatattcc
    16501 ttcccgcact gccagttcgc gcatggtgtt ttccgcttct cgctgatgaa tatccagcac
    16561 ctcatccacc agcgaagcgt tgaaaatccc cggcagatat tccgcaggcc agcggcgaat
    16621 gccgggaatg ctgctgccct cttccggctg taagccgaca atggtcaccg gtttgaattg
    16681 ttcgcgcata aagcgcgaca cgccggtaat ggtgccggtt gttcccatgc tggagacaaa
    16741 atgggtaatg cgcccgccgg tttgctgcca gatttccggc ccggtggtgg tgtaatgggc
    16801 gtaagggtta tcgggattat tgaactgatc gagcagcttt ccttcaccac gattagccat
    16861 ctccagcgcc agatcgcgcg caccttccat gccctgctct ttggtgacca gaatcagttc
    16921 cgcaccgtag gcacgcattg ccgcacggcg ttcctggctc atgttgtcgg gcatcagcaa
    16981 tttcatgcga tagcctttaa gcgcggcaat catcgccagc gcaatgccgg tgttaccact
    17041 ggtggcttcg atcaacacat cacccggttt aatctcgccg cgcttttccg cctcgacaat
    17101 catcgaaagc gctgcacggt cttttaccga tcccgccggg ttattacctt ccagtttcaa
    17161 ccagacttca ctgccgttat tcggccccat tcgctgcaac ttcaccagag gcgtattgcc
    17221 aattgtttgt tctaatgtac tcacgatctc tgtccatacg tggtgttgcc tgatgcgacg
    17281 cttgcgcgtc ttatcaggcc tacaggttac aaaccttgcc attaaaaagc ccggatcgcg
    17341 ggaagcgcct ccgggcgttt aacattcact caacctatca ggcgctttgt gcgagagcaa
    17401 gttcctcatc gcgggtttca atacgctcgt cgccgttata cagccgcgca tgttgcaggc
    17461 cgacgaacag acgatcgccg cgcactggcg catcatcccc gcgcatcacc accgtcaagg
    17521 gttcgtcata ccatcccagc ggctgcacca ctaattgggt gtagtgacct ttcgggctgg
    17581 cttccagtac ctgtacgggt agcggcgaat cgaggctggt acggcggctg atatccactt
    17641 cccacggacg caggaagaga tccaccggcc cctgatacgc aggtgtatag cccagcggcc
    17701 agcgatgtgc gccaacatgg aactgcccgc cgcgaatggt tccctgcagg cggttcactt
    17761 cgcccataaa ttcgagtaca aaacgggtcg ctggttcgcg ccatacctgg tccggtgcat
    17821 cagcctgctc gatattgccc tggctcatca ccactacacg atcggctact tcggtcgctt
    17881 cttcctggtc atgggtcaca aacacgctgg tgaatttcag ctcttcatgt aactgacgca
    17941 gccagcgacg caactcttta cgcacctgcg catccagcgc gccaaacggt tcatcaagca
    18001 gcagaatttg cggttctacg gcaagcgcgc gcgccagcgc cacacgctgt ttctggccgc
    18061 cggaaagctg cgcaggatag cggtctgcca gatgggcaag ctgcaccatc tccagcaatt
    18121 ttgtcacttt cgctttgata gctgcggcat tcgggcgctc gcgacgcggc agcaccgtca
    18181 ggccgaaagc gatattgtcg aacaccgtca tatggcggaa cagcgcgtaa tgctgaaaca
    18241 cgaaaccgac tttacgatcg cgcgcatgca ggcggctaac gtcggtgccg tggaagcgaa
    18301 tatgcccgct ggtttgatgc tccagcccgg cgataatgcg cagcagcgtg gttttcccgg
    18361 aaccggacgg ccccagcaat gcgaccatct gaccagaagg aatatccagt gagatatcgt
    18421 tcagcacctg ggtgcgacca aaagacttct taatattggc aatctcaatg ctcatgatgt
    18481 tcctcctgct gcgcgcgttt ttcctgattc tccagacgcc actgcaacat actctttaaa
    18541 aacagggtga taatcgccat cagcgtcaac aacgcggcag cggtaaagga gccgacggtg
    18601 ttgtagtcct gctccagcaa ttcaatctgt aacggcagcg aaagtgtttc gccgcgaatc
    18661 gagccggaaa ctaccgacac cgcaccaaac tcgccaatcg cgcgggcgtt ggtcagcacc
    18721 acgccataaa gcagcgccca gcggatgttc ggcagcgtga cgcgacggaa catctgccag
    18781 ccggacgcgc caagcaaaat cgccgcctcg tcttcctggc tgccctgact taacattacc
    18841 ggtaccagtt cgcgcaccac aaacggacac gtcacgaaga tggtgaccag taccataccc
    18901 ggccaggaga acataatttg cagattatgt tcatccagcc agccaccgag cgggccgtta
    18961 gagccgtaaa acagcagata caccagaccg gcaaccaccg gcgacacggc aaacggaatg
    19021 tccagcagcg tcagcagcaa ctggcgtccg gggaagttaa agcgcgtcac cagccaggcc
    19081 agcagaatgc cgaacaccag gttcaccggc acggcaatca gcgcaatcat caccgtcagc
    19141 cagatggcgt gcagcatgtc cggatcggcc agattctgta aaaccggcat cagccctttg
    19201 ctgaacgcct gcacgaagat gtaaatcatc ggcaccagca ggatgaacgc cgaaaccagc
    19261 atcccgatgc caatcagaaa ccatttgtcc cagttaatcg ggcgcgcgtc ataacgcttc
    19321 aattgtgtca cttccgccat taatgaccta ccacacgccg accaaagcga ctttgcagag
    19381 tgttaattga gaacagcagc aacagggatg ccgcgaggat caccgaagca atcgcgctcg
    19441 ccgccgggta atcaaactcc tgtaagcgaa caaaaatcat cagcgacgtc acttccgtct
    19501 tccaggcaat gttcccggcg atgaaaatca ccgcgccaaa ttcaccaaga ctacgggtaa
    19561 acgacagcgc cacgcccgcc accagcgccg gagaaagctc cggcagcacc actttgcaga
    19621 aactctgcca gcgcgttgcg ccgagcgttt ctgccgcttc ttcatattcc gggcctaact
    19681 cttccagcac cggctgcacg gtacgcacca caaacggaat actggtaaaa gccatcgcca
    19741 ccgcaatccc cagccaggta taggtaactt tgatatcaaa cttcgccagc cattcaccgt
    19801 aaaaaccgtt tacagaaaag agcgaggcca gcgttaaacc ggccactgcc gttggcagcg
    19861 caaagggtaa atccatcagc gcatcgatca gcgtgcggcc cggaaagcga tagcgggtta
    19921 agatccacgc catcagcagg ccgaaaacgc cgttaaaaat cgatgccaca aacgccgaca
    19981 gcagcgtcac tttgtaggcc gcgaccacct gcgggttggt gatcacctcc cagtactgtg
    20041 cccagctcat ctcagagagc tgcatcacca gcgctgagag cggcagcagc aaaatcaggc
    20101 acacaaacag cagactggtg ccgaggctta aggtaaagcc cggcagcacg cgtcttgatg
    20161 aaactgcaaa cattaattac gccccgccgc taacagcttg tctaactcgc cgccgctggt
    20221 gaagtgggtt ttcatcactt ccggccagga gccaaatttg tcttccacgc ggaacagctc
    20281 ggtctgcggg aatttgtttt tcagtttgtc catgacttcc gggttattta cgcggtagta
    20341 atagtcggtg atgatggtct gcgcctgcgg gctgtagagc cagttcaggt aggcttttgc
    20401 tgctttttcc gtaccgttgg cctgcacgtt tttatcgacc cacgccaccg ggaattccgc
    20461 aagaatgtta gttttcggaa taactacttc gaagccctgc gcttcatact gtttacggat
    20521 gttgttcact tccgattcga agctaatcag tacatcgccc agcccacgtt cggcaaaagt
    20581 ggtggtcgcg ccacgaccgc cagtatcgaa cacttcaacg tttttcagga actgagtcat
    20641 aaactgttca gttttggctt tgtcgccacc gtcggctttg tccgctgcgc cccatgccgc
    20701 aaggtaggtg taacgcgcgt tacctgacgt tttcgggttc gggaaaatca gcttcacgtc
    20761 ggagcgcacg aggtcgttcc agtcgtgaat attcttcggg ttgcccttac gcaccaggaa
    20821 gcccatggtg gagtagaacg gcgagctatt attcggcagg cgcgactgcc agtcggccgg
    20881 gataagcttg cctttgtcat gcaggatttg tacgtcggtc acctggttat aagtgacaac
    20941 gtctgctttt aagccctgca aaatcgccag cgcctgtttt gatgacccgg catgagattg
    21001 ttttatcgtc agtttgtcgc cgccgttatc ttttgcccat tgttgctcaa acggcggatt
    21061 cagggcggca aacagctcgc gggagacatc ataagaactg ttcagcagtt ccgttgcctg
    21121 tacatggccc gccagcagca gagaagcgac cagcgcgagt gagttctttt tcagtaagtt
    21181 aacggccatt gcgcaccctt ataaatttaa cgactttcta atagccatca tatttataac
    21241 ggacgtgaaa ggagtaacgg ttttatatac cgtttggtga tttggaagtt gaaaagggaa
    21301 taagacgaaa tcctccccac aaatgcaggg aggaaacaga ggtgaatcag atgccgacgc
    21361 taaccgtctc cggtagtgtg ctgccgccat caatcacatt ctgtgtaccg gttaaatagc
    21421 tggattcatc cgatgcgagg aaggccgcca gttcgccgac ttccagcgga tcggcgaggc
    21481 gacgcatcgg gattgctttc gccatttcag tcagcaccga ttctggatct tccgggttcg
    21541 actggcgggc aatgctttcc gccattggcg tgcgaacgta tccagggcag atggcgttaa
    21601 cgcgaatacc agactgcgcg tactccaccg ccagcgattt agtcaggcca acaatcgccg
    21661 ctttcgttaa ggcgtacgcc gtttcgcccg ggtctgccac catatcgcca gtgactgaag
    21721 acatcatcac aatgcggcca tctttgcggg caatcatctc cggcagcacc gccttcgtga
    21781 cgttccatac gccttttata ttgatatcaa tatggaaatc gcgatcttca tcgctcatat
    21841 cgaggaaact gcccagacga caaacgcctg cgttattcac cagaatatca atgcgccctt
    21901 ctttttcctt agcgcgctta atagctgcgg ctaccgacgc cgggtcacgc acatcggcga
    21961 caaccgccgt acagcgatga ccacggccac acagttcgtc cgccagcttt tcgatctcag
    22021 gggagatatc cagcaagatt aggtttgcgc catgacgcgc aaaagttctg gcaattcctt
    22081 cgccaattcc ctgcaatgcg cccgtaatca gtgctgtctt gcccgtgagt ttacccattt
    22141 taatgctctc cttgttaata cagagcgtta cactccattc cctctgaaaa tacaggataa
    22201 acaaaatatt gctgcggatc agctcactaa ttcaggaaaa tctcaatcca gtcgctgctt
    22261 tatgcatcat ttcaggcgtt gcgttagctc actgctgcgc tcaatcattt tcaatgactc
    22321 cacatcattg agttgcacaa ggccaacaaa cagtaaatcg gtaacagaat tttgcgccgt
    22381 gcgggtggac atcgacgagc tgcgccattc ggtttcgcca gaaacggtat cgagggtgta
    22441 atgcgccagc cgccgcagcg gggaatcggt taatgaggta atggcaatca ccgtcgcccc
    22501 ctgctttcgc gctgcctcgg cgcacaagac aatctctttt ttactgccac tgtaagagat
    22561 agcgatttgt acatcgcctt tttttagcgc ctgagaaacg gtggcttgta cgtgggtgtc
    22621 ggcctcacag gccacgcgat aaccaatttt catcagtttg aacgacagat cgcgccccac
    22681 cagcgccgac ccgcccaggc ccgttatctg gataaacggt gctttactga tgacctcaat
    22741 gattttttgc agccgcgcgt agtcaaacaa cgcgcaggtt tgctccagcg cctgctcttt
    22801 ttcgcgattc agtttacggg caatcacttc cagcgaatca tcactggtaa tcgaactgtg
    22861 caggtgcagc gccgtggcat tcgttttctc ccggctggca ctgtattcgc caattaacgc
    22921 catacgcaat tcagtaaatc cttgcgcgcc gagcttctgg gcaaacttca caatactcga
    22981 ctggctgatg ccgagctgtt tcgccatctt gcgcgaagag acggatttca gctcactcac
    23041 gttggcccgc agaaagtcag caattttttg ctcgttcccg gtaaattcac tttccgcatt
    23101 gcgtattttc gtcaggtaca acatcttcca ctctcctggg ctggcagcaa aaattccgct
    23161 taagttctta tgacgctctt cacactctgc gagtgtagac tcaatgattc ctttaagtct
    23221 gtcaattcgg gatatatgat tccatacatc tgcaattatt tgatcgtaaa tagtaaggtc
    23281 accaccgatg caacttgaaa agatgattac cgaaggctcg aacgccgcct cggctgaaat
    23341 tgaccgcgta tcaacgctgg aaatgtgccg gattatcaac gatgaagata aaaccgtgcc
    23401 gcttgccgtt gagcgcgtac tgccggatat cgccgcggcg atcgatgtta tccacgccca
    23461 ggtaagcggc ggcgggcgtc tgatttacct cggtgcggga acatccggtc gtctggggat
    23521 tctggatgcc agcgaatgtc cgcccaccta cggcgtgaaa ccaggcctgg tagttggatt
    23581 aattgctggc ggcgaatatg ccattcagca cgcggtggaa ggcgcggaag atagccggga
    23641 aggtggtgtt aatgatctga aaaacatcgg attaaccgcg caggatgtgg tggttggcat
    23701 tgcggccagt ggtcgcacgc cgtatgtgat tgccgggctg gaatacgcac gccagctcgg
    23761 ctgccgtaca gtgggaattt cctgtaatcc ggggagcgct gtttccacca ccgctgagtt
    23821 tgctattacg ccggtggttg gggctgaagt ggtcaccggt tcttcgcgga tgaaagcagg
    23881 cacggcgcag aaactggtgc tcaatatgct ttccaccggg ctgatgatta aatccggcaa
    23941 agtgttcggc aacctgatgg tcgatgtggt cgccaccaac gaaaaactgc atgtgcgcca
    24001 ggtcaatatc gtcaaaaacg ctaccggatg tagcgcagag caagcggaag cggcattggt
    24061 tgcctgcgag cgcaactgta aaacggccat tgtgatggtg ctgaaaaatc tcgatgccgc
    24121 agaagcaaaa aaacgcctgg atcaacacgg cggctttatt cgtcaggttt tagacaagga
    24181 ataacccatg gccaaagaga tcagcagtga acttctgaac accattctta cccgggtcgg
    24241 tggaccggga aatatcgcca gttgtggtaa ctgtatgacg cgcctgcgtc tgggtgtaca
    24301 tgacagttca ctggttgatc ccaatatcaa aacgctggaa ggcgtgaagg gcgttatttt
    24361 gaccagcgat caggtacagg tcgtttttgg accaggtaaa gcgcatcgtg ccgcaaaagc
    24421 gatgagcgaa ctgctgggag aagccccggt acaagatgcc gcagaaatcg ccgctcagaa
    24481 taaacgtcag ttaaaagcca aacaaacctc cggcgtgcaa caatttctcg ccaaattcgc
    24541 caccatcttc accccgctga tccccggttt tattgccgcc ggtctgctgc tggggatagc
    24601 gacgttaatt gccacggtga tgcacgttcc ggcagatgct cagggcacgc tacccgatgc
    24661 gctgaatttt atgaaggtgt tcagcaaagg cctgttcacc ttcctggtaa ttctggtggg
    24721 ctataacgcg gcccaggcat ttggtggcac gggcgtaaat ggcgcaatta tcgccgcgct
    24781 ctttttgctc ggttataacc cagctgcaac cacgggttac tacgccggat ttcacgattt
    24841 ctttggtctg cccatcgatc cgcgcggcaa tattatcggc gtgttgattg ccgcgtgggc
    24901 ctgcgctcgc attgaaggca tggtgcgccg ctttatgccg gacgatctcg acatgctgtt
    24961 gacctcgtta atcactctgc tgatcaccgc cacactggcg tatttgatca ttatgccgct
    25021 gggtggctgg ttattcgaag gcatgtcgtg gctgtttatg cacctgaaca gtaatccgct
    25081 cggttgtgca gttttagcag ggctattcct gatcgccgtg gtgtttggcg tgcatcaggg
    25141 ctttattccc gtttacctcg cgttaatgga cagtcaggga ttcaacagct tatttcccat
    25201 cctttcaatg gcaggtgcgg gccaggtggg cgcggcgctg gcactctact ggcgggcgca
    25261 accgcatagt gcattacgca gtcaggtacg cggggcgatt attcccggtc tgctgggcgt
    25321 tggtgaaccg ttgatttacg gtgtcaccct gccccgcatg aaaccgtttg ttaccgcctg
    25381 tttaggtggc gcggcgggcg gtttgtttat cgggctgata gcctggtggg gcctgccgat
    25441 gggcttaaac agtgcctttg ggccgtctgg tctggtggcg ctgccgctga tgacttccgc
    25501 tcaaggtatc cttccggcaa tggcggttta tgcaggtggg attctggtgg catgggtttg
    25561 tgggtttatt ttcaccacgc tctttggctg ccgtaacgtc aatctggact gataatatga
    25621 aacggacaat gctctgcctt tctctgctgg ctgtcagctg tagcgtcagc gccgcaaaat
    25681 accctgttct gacagaaagt tcgccagaga aagcagggtt taacgtcgaa cggcttaatc
    25741 agatggatcg ctggataagc cagcaagttg atgatggtta tcccggcgta aacctgctga
    25801 ttataaaaga taatcagatt gtttatcgca aagcctgggg cgcggcgaaa aagtatgatg
    25861 gcagcgcgtt aatggcgcag ccgttaaaag ccaccaccgg gacgctgtat gatctggcct
    25921 caaacaccaa gatgtacgcc actaacttcg ccctgcaaaa gctgatgagc gaaggcaaac
    25981 tgcatcctga cgatcggatt gcgaaatata ttccagggtt tgccgacagc ccgaacgatg
    26041 cgatcaaagg caaaaacacg ctgcggattt ctgatctgct gcatcacagc ggcggtttcc
    26101 cggcagatcc gcaatacccg aataaagcgg tcgcgggcgc gttatattcc caggataaag
    26161 gccagacgct ggagatgatc aagcgcacgc cgctggagta tcagcccggc agcaagcata
    26221 tctacagcga tgtcgattat atgctgcttg gatttatcgt cgagtcggtt accggtcagc
    26281 cacttgaccg ctatgttgaa gagtcgattt atcgcccgct cggcctgacg catacggtgt
    26341 ttaatccgct actgaaaggc tttaaaccgc aacaaattgc cgccacggaa ctcaacggca
    26401 atacccgcga tggcgtgatt cacttcccga atatccgcac ctccactctc tggggtcagg
    26461 tgcacgatga aaaagccttt tattcgatgg gcggtgtttc cgggcacgca ggtttgtttt
    26521 ccaataccgg cgatattgcg gtgttaatgc aaacgatgct gaacggcggt ggctatggtg
    26581 atgtgcagct gttcaatgca gaaacggtga agatgttcac caccagctct aaggaagatg
    26641 ccacttttgg ccttggctgg cgcgtgaatg gtaatgccac catgacgccg acgtttggca
    26701 cgctggcaag cccgcaaacc tacggtcaca caggttggac cgggacggtg accgttatcg
    26761 atccggtgaa tcatatggcg attgtgatgt taagcaacaa gccacattcg ccagttgccg
    26821 atccacaaaa aaatcccaat atgttcgaaa gcggtcagct accgattgca acttatggtt
    26881 gggtagttga tcaggtgtat gcggcgttaa agcagtaata aaaaggccag tcagttgtgt
    26941 tactggctgg cctttaatca atgaatcaga aacgcttaca gcgccatcaa cttgtccagc
    27001 gacggcgcaa agtaatagcc gccggttacc ggtttggtga aacgcaacat cgcatcacgc
    27061 ttaccatcgg tatcgccaaa catgctcagc agttgctgct caatgttatg cagacgcgcg
    27121 cagtaggcgc agaagtacag accgtgcgta ccgctggcgg tgccgtacgg caggctctga
    27181 cgaacaatct tcagcccttt gccatcttct ttcagatcaa cgcgggtcag gtgagaggtt
    27241 tccggacgtt cgtcgccgtc aatctcttcg ttggcctctt tggtgcgccc gatcatcatc
    27301 tcttgatcgt gaacgctcat ccgattgagc tgtttcaggt tgtgctccca acgctgcaca
    27361 aacacatagc tgccgcccgc atccacgccg tctttgataa cagccacttc gcggcgcgtc
    27421 tcttcacccg ccgggttttc tgtaccgtca acaaagccgc tcaggtcacg ctcttcaacc
    27481 caacggaagc cgtggatctc ttctttcact tcaatgcagt caccaaaggc ttccatcgcc
    27541 gcctgagcga cagagaagtt tacgtcgtga cgcagagaaa gaatgtggat caacacatcg
    27601 aactgggtcg tcggcgcaag gcctttaccg tagcccggaa aatctttcag ctcttcggcc
    27661 ccaacgccgc cgctcagagc gcgccaggta ttgttaccaa aggcaaccac cgcaccaaga
    27721 tgcgcgtccg ggaatttcgc ttcaaaagtt gccagtttgt cggcaaatgt tttactggcc
    27781 gcacgcaggg cgtcaacttc ccctttcacg ttggcttcga tccaaatcgc cgcgcggcaa
    27841 tgttctggca aaatgccact ctgaacctga gacattgttc ctcctgaaaa taataatgcc
    27901 acgcaatccg tggcattgtt gggcgctatt ttacgtgttt tttcgcggcg gcggtttgtt
    27961 cagacgcaaa ttaacgccgc cagataattt tactgacttt ccagtttttc agggtatcgt
    28021 ccgaaggcat taacccttca gggccactcc attccccgct gaactggtag ctaatatgtt
    28081 gactgccttc ggctttacat tcgacggcac gattatcatc actgtcggcc ttttggcaat
    28141 tgccaaatgc tttgctgtaa aggtcactaa acggtgtacc gattttaaca ccggtgtcag
    28201 caggaatatc gctatccagc acatcaatgc ggctgatcgt gccttgatca ccgttaatca
    28261 ccatcgccac gttgtcgcct ttcatcactt caaaaaagcg caccacgttg ccgttcgcgg
    28321 ttttcattcc gctgcgcagg cgataatcgc catcaagcgc atcagcaatg gcttgttctt
    28381 gcagtggtgt ggacgccgtt aattcaccca cgccctgctc gctcactttg gtggatgatc
    28441 caaaccagtt ccacgggtta gcggccgacc agttaactga cgacatcgtg gaacagccgg
    28501 tcagcatcaa cggcatagcg cataacatta aacgcagcga tttcatgtca cttcctttgg
    28561 ttattcaata acgttgcttg gagtgcaaat tcaccaaaaa gtgccgttat tctttttctt
    28621 cattaaaaca agcgcgtaaa cgtcgattgg tcagcagcca gattaacgcc acgatatccg
    28681 ccactaccag cgccagaccg ataccgctaa cggattcacc gttcagccac agccacggtt
    28741 gccaacaaag taaaaccacc tgcgccaaca gcaacagaaa atagagcaca tgccagatac
    28801 ggggaaatga agcccgccga ccactcagca aaaatgccag caccgccgga ataccgggaa
    28861 tcaaccccag ccagaaatta tcgtgatcgg gataaaacag atttagcagc gcagtaccct
    28921 gctcgcgcga cgcaccggca atgacaaaca gcacccaggt tcgcgcctga agcaatagca
    28981 caagccagaa gagcaagggt aaacgcaggc gaccgtgcgc atcataatgg acaggatgaa
    29041 actcagtact cttcatcttc aatcaaacgc ttacccagac tcagtacgtc ggcgtgttca
    29101 tatcccaggc gttcatacat tccgagcacc atgtcgttat cttccggcac gttgatctga
    29161 attttcggac agccgcgagc aatcagcttt ttctccaacc gattaagcaa cgcattagca
    29221 atcccacgcc cacgaaactc tggatgcacg ccaagataat aagcagaccc gcgatgcccg
    29281 tcataaccgc ccatcaccgt tccgaccact tcaccgttta cctcagcgac cagaaacaaa
    29341 ctgacgtcat ggttcatctt acgctcgatg tccatttccg gatcgttcca cggacgcagc
    29401 aagtcgcaac gctcccaaag ggtgatgacc tcttcgaaat cttcctggcg aaatacgcgt
    29461 atctccatgg tattcgttac ctttttgcgg gttaaaaggc tgattatggc gtgaacggtc
    29521 gaattagcca atatctgacg aaaatcggtt gaaaaagtgg cataatgggg agttgtcaac
    29581 tattgaaatg aaaagtaaaa caattctcaa cagcaaacgg tcgtaacgga ttacgcgata
    29641 cgatataaca tctggaactt tattattaca actcaggccg tatgagcact tttaaaccac
    29701 taaaaacact cacttcgcgc cgccaggtgc tgaaagccgg tttggctgcc ctgacgttgt
    29761 caggaatgtc gcaagccatc gccaaagacg aacctttaaa aaccagcaac ggacacagca
    29821 agccgaaagc caaaaaatct ggcggcaaac gtgtcgttgt tctcgatcca ggccacggcg
    29881 ggattgatac cggagcgatc ggacgcaacg gttcgaaaga aaaacatgtg gtgctggcga
    29941 ttgctaaaaa cgtccgttcc attttgcgta atcatggcat tgatgcgcgt ttaacgcgtt
    30001 ctggcgatac gtttatccca ctatacgatc gcgttgaaat cgcccataaa catggcgcag
    30061 atctgtttat gtcaattcat gccgatggct ttaccaaccc gaaagctgcc ggtgcttcgg
    30121 tatttgccct ctctaaccgc ggtgctagta gcgcaatggc gaaatacctg tctgaacgcg
    30181 aaaaccgtgc tgatgaagtt gccggtaaaa aggcgactga caaggatcac ctattgcagc
    30241 aagtgctgtt tgatctggtg caaaccgata ctattaaaaa cagcctgacg ctcggctcgc
    30301 atattctgaa aaagattaag ccggtgcata aactgcacag ccgcaacacc gaacaagccg
    30361 cgtttgtggt gttgaaatcg ccgtcggttc cgtcggtgct ggtggaaacc tcgtttatca
    30421 ccaacccgga agaagagcgg ctgttaggca cggcggcgtt tcgccagaaa atcgccacag
    30481 cgattgccga aggagtgatc agttatttcc actggtttga caaccagaaa gcacactcga
    30541 gaaagcggta agtgatgaaa cccgacgcac acctggttaa acagttcctg ctcaaccttc
    30601 aggatacaat ttgtcaacaa ctgaccgccg tcgatggcgc agagtttgtc gaagatagct
    30661 ggcaacgtga agctggcggc ggcgggcgta gtcgggtttt gcgtaatggt ggtgttttcg
    30721 aacaggcagg cgtcaacttt tcacatgtcc acggtgaggc gatgcctgct tccgccaccg
    30781 ctcatcgtcc ggaacttgcc gggcgcagtt tcgaggcgat gggcgtttca ctggtagtgc
    30841 atccgcataa tccgtatgtt cccaccagcc acgcgaatgt gcgctttttt attgccgaaa
    30901 aaccgggtgc cgaacccgtc tggtggtttg gcggcggctt cgacttaacc cctttctatg
    30961 gctttgaaga cgatgctatt cactggcacc gcaccgcccg tgacctgtgc ctgccatttg
    31021 gcgaagacgt ttatccgcgt tacaaaaagt ggtgcgacga atacttctac ctcaaacatc
    31081 gtaacgaaca acgcggcatt ggcggcctgt tctttgatga cctgaacacg ccagactttg
    31141 accactgttt tgcctttatg caggcggtag gcaaaggcta caccaacgct tatttaccaa
    31201 ttgtagagcg acgtaaaacg atggcctacg gcgagcgcga gcgcaatttc cagttatatc
    31261 gtcgcggtcg ttatgtcgag ttcaatctgg tctgggatcg tggcacactg tttggcctgc
    31321 aaaccggcgg gcgcaccgag tctatcctga tgtcaatgcc gccgctggta cgctgggagt
    31381 atgattatca gccagaagca ggcagcccgg aagcggcgtt aagtgggttt attaaggtca
    31441 gggattgggt gtaactccct cacccccatt cccgcatccg ctgatgcagc gtcagtgacg
    31501 gcttctcggc aaacagttgc tgataatccg tggcgaattg ccccagatgc cagaatcccc
    31561 actgcatggc ggcgtctttt accgtcatac tttgcgacca cgggcttatc agttcgcggc
    31621 gcacggcgtt caggcgaatg cgtttcagcc acgcgtttgg gccaatgcct aaaatagcgt
    31681 gaaaagcgtt ttgtagcgtg cggcggctga catgtagttg attacacaag tccagcaccg
    31741 tcaccggttc ggacatgttt tccagcacat attcacgggc gcgggaaagc aatcgacggt
    31801 aactctgatg actgatgctt tccgccgtca ccattggctg cgcttcttcc agcatcgccc
    31861 ccatcgccat tagcaagtta tcccccagca cttttcgcac tgcaggctga tggagatttt
    31921 ccgggttctc gcaaaacgtc gccagcgcct gttggacaaa gccccacaga gcggctttat
    31981 gctgctcttt cacttccagc gccgactggc tacgcagcat atgtaatacc cgatccggat
    32041 tatgcaaaaa gttagcctga cgagtgatga catcttcaga aagcactacg cccaggatcg
    32101 tgtaatcgtc cggcgtactt aattcaaact cggttccacc cgggcgcgtc gcaatttctg
    32161 cgcttcccag acattgcgaa ccgataaatc cctgctcacc gcgcgtcgcc ggaatgccaa
    32221 accagaacga gttcggccag accaggcacg actgacgcag cgccagacca gtgtattcac
    32281 gaaaaacctg aatatcatcg agtagaattt ccgtaaattc accatgaaac ttgcccggat
    32341 gcagctgatc gtaaatctgc tgccaggcgg taattgtcaa agcatgttca tagacatccg
    32401 ttgtctgtcg ttgatgaaca ttatccactt cgaccttcgg cgtgagcttc aggttttcgg
    32461 gtaagggttc atgataaaga tggtgcaaat tggctgtacg ggtctttttc atgatgttaa
    32521 tgccgggtgt tgtaggacac ccggcacctc cgacaggtta atggggcttg agacgataac
    32581 gactactgcg tttacgtaac gtcccggcag aaaagagctg ttcgagcgca tttctggctt
    32641 tttccagcgg ccagccaaag tgggctgcca cttctcctgc cgtcattccc tgacgtactg
    32701 atgttaacag cgccaacaac tcgtcagcag attccgcgac gataactggc gcgtcgggtt
    32761 cctttacggg ttgcttcggc tggcggttaa agccagtaac cagccactgg gtgtcatcgt
    32821 ctggccgacc gatctcctta cggctgatga cacgcccggt acgcatcgcg gcagcacaac
    32881 ctgcgtccag cgccgcacga cacgccgcca gatcgccttc caccaccagc gttaggcgac
    32941 cagggtcaag cacttcatgg ctgagcagac gaacgttagc tgctttgagc atggcatccg
    33001 ctgcatctat cgcggcgacc atgccgtcaa cttccagcaa tcccagtgca ttgatcatcg
    33061 gcaacctccg ttacgcacgc tggattggat tacgcgcgat ttccagcact gcatcggtaa
    33121 aggcgttaca ggctgcttta cacgcggcct ggctaccggt taaaaatgct gccgagtagt
    33181 tggtttcaga cggtggcggg acataggtca ccagctgcac gtcggcagat ttcaacgctg
    33241 catcaatgcc gtaggtcgct tccagcggcg gtgccaccag atacgccatc ggatcgccaa
    33301 gcgtgatccc ggcggttgat gagagataag aaccggtacg cgaaacgaca tgtgccagga
    33361 aggctgtgtt ttctgcgtca ttagcccact ggaaagcagc gccattttca atatttgcaa
    33421 ccatcgcatc cagaccagca cgcacttccg ccgggtttgg cccacccagc ataatcagca
    33481 cctcaccggc agtcggtgac gggccgtgtg cagcgcccgc atacagcgag cgaccatata
    33541 ccacttcgac catcgcctgc ttggtcgctt cgtcagccgc aatgtaggtg acgtcatctg
    33601 aatcagcaga aatcagcccg aggctacgaa tatgcggcgg caatttcagt tcacgtgcaa
    33661 attcggcgtt aacggaggca atcacccgca tggcggttac cgacggtcga atcaaatcta
    33721 aagctggcat gatgcctcct tatcgggtca tgttgatgcc ggatgctttc tgctccagca
    33781 tacgtttcgc caaatccaca atgacggctg cggcttcaac cggcggcgtg ccgccctggt
    33841 gaatgttaga gatacaggtg cgatcggcct caacggtggt cgccatacgc ggcgaataaa
    33901 cggcgtagca ggagaggctt tctgactgcc ccaaccccgg acgttcgccc accagcagga
    33961 tcactacttt cgcgccgagg atctcaccga tctgatcttc aatcttcacg cgaccataac
    34021 gaacaaagaa tggcgtgccg actttcagcc cggcctgttt caggcccgcc atcagcggcg
    34081 gcaggatctc ttcgtagttc acggtgatcg catcagttga caggccatca gaaataacga
    34141 cctgcacgtc cggattagca acacactgtg ctttcagcgc ttcaacagct tctgcacaca
    34201 ggcggcggcc catatccggg cgagtcaggt agagattttt gtcgctgatt tcggagcgga
    34261 cttccagcaa gccctgcgct ttcacccact cttccggtac ttctttcaga acggtatctt
    34321 tcgaacgaga gtgatcggcc aggaaacgca gcaacgcctg ggtacgcgga cgcggaccgg
    34381 cacgaccggt acaaacacgg gccacggtgc tgcgacgcag ttctgttaat acgtctgcgc
    34441 gatgcgggtt ttcaacacca atccacgctt ttgcttccgc agaacctaaa tccagcgcgc
    34501 agctttccga ggtcaccggt gccgcacagg tggtggtggc gcactttgct tctgacggcg
    34561 cgggggccgc ttgtcccatt gacgccatca cgctgcgtac aatttcttca atctgttttt
    34621 gatccatgat gtgttatctc cgcgtcatca gaagaacagt gacggatcgc ccgcccgttt
    34681 ggtcaggcga ccgtttgcca taatgcccat gctttccagc cagcgttcaa actccggtga
    34741 cgggcgcaga ttcagtaact gacgcacagt ggcagtgtcg tggaatgcgg tggtctgata
    34801 gttgagcatg atgtcatcac ccagcggcat ccccatgatg tagttgcagc ctgcggtggc
    34861 gagcaggatc atcaggtttt cgttgaggtt ctggtcagcg tcagcgtggt tggtgtagca
    34921 gcagtcacag cccatagaga tgccgctcag cttgcccata aagtgatctt ctaagcccgc
    34981 gcggataatc tggcggtcgt tgtagagata ctccggccca ataaaaccga ccacggtgtt
    35041 gacgataaac ggatcgtaat gacgcgccag cccatagtta cgcgcttcca tcgtcacctg
    35101 gtcagcgccg aagttagcgc cagcggacag cgccgaacct tgtccggttt cgaagtagag
    35161 gcagttttcc ccggcgatac ggttaaactc tgcacccact gcgcgcgctt cgtcgagcat
    35221 cgccagctcc acgccaaact ctttcagccc tttttcgctg ccgcaaatac tctggaaaat
    35281 cagcccgccc ggtgcgccgc gacgaatcgc ttcgatctgg gtggtgacgt gcgccagtac
    35341 gcagccctga gttgggatgt tgaatttgtc gatcacgccg tagatggtgt ccagcacgcg
    35401 gcttaagttt tccacgtcgt ccgtcaccgg gttgacgccg atcaccgcat cgcccacccc
    35461 gaaggaaagc ccttcgtaga tttgcgcagc gatactttgc acgtcgtcac gggtgtcatt
    35521 tggctgcaaa cgggcgctga aggtgcccgg aataccaata gttgtattgg cctttttgat
    35581 taccggcatt ttcttcgcgc cgtagatcag gtccgcgtta gaactgatct tcgccaccgc
    35641 cgcgaccact tccgaggtca accctttgcg agtaaaggca atgtcgtcaa cgctggtttc
    35701 gtcgctcagg acatactcac gcagttcgct gatgctccag tttttaatct ggttgtaggc
    35761 cgtttcgtta acatcgtcct gaatcagccg cgtcacgcag tcatcttcat aggcaatcac
    35821 cggattattg cggatgtccg ctacggtcat ttccgacaac acctgctttg ccgccacgcg
    35881 ctcctgtgag cttgccgcag caacgcccgc cagcacatcc cccgaacgca gttcgttggc
    35941 tttagccagc acctctttta catccttaaa ctgatataca ttgccgaaca atgtggtctt
    36001 tagtttcata agtcgttccc tcaggaagga aatgcgagtg atttcaccgt caccggcaca
    36061 accgatccgc caaaaagagg cgtaccaatg tcgatatagt cccccgcgcg gacaatcact
    36121 tcgtcaatga ctgccaacgg gagttgttgt agctgtgggc gcaacaacat gcccagagct
    36181 ttaccaaagt cctgcccggc caccaccagc aggggatgcg gattcggaaa acgcgcgacg
    36241 aaatcgacca acgcgttgat gaccgtcagt accgcggcgt aacgcacagg cagcgaggcg
    36301 ggaagcgcca gcacgtacgc atcagttttg ggatcaagat ccagttgaat cagcgcctgt
    36361 tgccaggcac tcaccagatc cttttcatca attgggatcg ccaccggcaa gttgcgcagc
    36421 ggcagttgta cgccctccag ccagattgtg ctgccagaga gcgaaagggt atgtgcaccc
    36481 gcgccaatca ccgtggcgcg cacggtttgc gccggaaact gcacgttcat ctcacgcagg
    36541 cgcggatggt catgcagcgc cgttgccaga agcgggccaa tatcggcaaa acagaacggg
    36601 tcggcgggct ggtggcgata acattcgccc acgccgccag aaagcgtaat gatttcgggc
    36661 gtaacacctg cgggcagcaa accggtttgc attaatgcct gcgcgagcgg cgaaagcgtt
    36721 ccgtcaatca cttcgacaat cagctctgcc atccgccggg taacctgcac cagctgcgcg
    36781 ccggtcagcg aacgggcgtc ggtgcctgcg ccgaagcact catccacaat catctgcccc
    36841 ggtttatgag cgtaaaccac gcgcccctgg ctgtcggttt ccagcaggcg accgccgaca
    36901 ttgaggcagg cggtgccgct gatttttccg gcatcgaaca gggcgtagtt cgcggtacca
    36961 ccgccgatgt cgatattcag tacccgacac agccgttgtt cagaaagggt ttgcgccccg
    37021 gcaccgtgac cggcgatcac ggattcgaga tgcggtccag cgctggcgac gacaaaatcg
    37081 cccagcgacc gggagagcgt catcaccgcc gggcgagcgt tgcggttttt cgcgctttca
    37141 ccggtgatga tgatggcacc agaatcaacg ctttccggcg caatgcccgc agcctgatat
    37201 tgctcgagga ttaaggtttt cagttccgct tcttttaaac caccctgttt atcgacaggg
    37261 gtaaagaaca ccgggctttg ccagctaatt tcgcgtttga tgaattcgta gcgcggcacc
    37321 tgcgacaccg ccgcacggtt aaccagctcc aggtgggaga aaatcacctg ggtggtggtg
    37381 gtgccgatat cgataccgac gctcagtagc tggcgagtgt tcacgattgc gcctccgctt
    37441 cggttttagc cgcgctcgcg tcttctttag gtaccagcat catcgccacg ccaatcgccg
    37501 ttacgccgcc gatcaacttg ccgacaatca tcgggaagat catggcgttc atgttggcag
    37561 cggcgaagcc taagtggtcg cccagggcga aagcagcgga aacggcgaag gcacagttga
    37621 tgactttgcc gcgggtatcc atctgcttca tcatgccaaa catcgggatg ttgttggcaa
    37681 gcgttgccac catgccggct gccgcgatgt tgttcatatt cagcacctta ccgacgctca
    37741 tcagcggttt ttcaaaccag cgagtcagca gcagcaccat cggatacgcc cccagcagca
    37801 cgcaggagat agaaccgata acttcaatgg cgcgcatcac ttcaccgggt ttgtcgcctg
    37861 gagccatgaa gatcggatcc agaccgggga tcagttccca accgagcagg aatttcacta
    37921 ccgcagcggc aagaccgagg gtgatcaatg caacgaggaa tttggcgaag atctggaagc
    37981 cgttgatcat tttttccggg atgaatttca gccccagcgc caccagcacc gcaacgataa
    38041 gtaccgggat catgttcatc aggatcagcg caaaggtgaa ttccaccggc tgaccgttga
    38101 tctgcacacc ggagtacata gcaaccagac caccagcaat acagccaatc ggaatggtca
    38161 caatgcccgc cagcacgccg agcgccagat aacgacggtc agaaggttcg ataatgccga
    38221 gcgccaccgg aatggaaaac acaatcgttg gccccatcat cgacccgaga attaacccag
    38281 agtatagcca cgctgctacg tcgccgcccg ccagctcttt ggcgaggaag aagccgccca
    38341 tatcgcacgc cagcagtgtt ccggcgaaca ttgacgggtt tgcgccgagc atttcgtaaa
    38401 ccgggataat caccggtccg agtacgtggg ccagaacagg tgccagcgcg gtcataccaa
    38461 ccatcgccag gcccagtgcg cccatcgcca taaagccttc ttcaaactgc ccgccggatc
    38521 cttcgatact tttaccgaac ttaccgagga aacgagcaga accgccgaac tgcgacagga
    38581 tcctgtctac ggcagctatc agcataaaga acatcatgat gtacatgatg atttcgttaa
    38641 ttcccatcgc ctttactccc tgttagttgt tatttattgg cggatgcggc gtgaacgcct
    38701 tatccgccct acatgtgcaa tcccgtaggc cggataagac gcggcaagcg tcgcatccgg
    38761 catttattgc gccgctgcgt acaggccgac aatctgctcc aggctggcgg tacgcgggtt
    38821 gctgcgcaga caaatatctt ccagcgcggc ctgcgcccat gcgccgtaat gcgcagatgt
    38881 cgcaccaaca tcgcccagtc gtttaccaat cccaacttca gcaatcagct cacttaccgc
    38941 gttaatagcg tcacgatcgt cggatttttt agttcgcagc gcccgaccaa tctgactaaa
    39001 ccgatcacga caaaccatcc ggttaaattc catcaccgtt ggcaacaaca tggcgttcgc
    39061 cagaccgtgc ggaatatgca gcgccgcccc tggctgatgc gccatcgcgt ggcataaccc
    39121 aagcccggcg ctggaaaacg ccattcccgc catacatgaa gccagcaaca tgctctcgcg
    39181 cgcggcaagg tcatggccgt agcccaccgc tttcggcagt gatttgccaa tcatcgcaat
    39241 ggcaccaatc gccaggctgt cggtaaacgg tgtagcgttc agcgcgctgt acgcttcaat
    39301 ggcatgggtt aacgcatcaa tgccagtcat cgccgtgaca tgcgacggca cgccttcggt
    39361 caacgcggcg tcgagaatcg ccacatccgg catcagcgag gcatgggcta acacctgctt
    39421 gcgcccgctc accgcgtcga taatcaccgt tacgttggtg gtttcagagc cggttccggc
    39481 ggtcgttgga atggcaatca acggcaggcg cggttgcaga acgctggttt ctgacatttc
    39541 tgccagcgtg ctatcggggt tcgtcaccag caacgccacg gctttcgccg catccagcac
    39601 cgagccgccg ccaaacgcga tcaccccgtc acaacctgat tcacgcaact gcgccacggc
    39661 tgcacacacg tcggtgatgc atggttcgcc caccggacat ggccagagcg tcatggcgat
    39721 acctttaacg gccaggctac gcgtcagccc ggcggtcatc cctgcctgat gcaaaaagct
    39781 gtctgccatc acgaacagat gtttcaaccc acgcgtttgc gcttgctgcc cacaactgct
    39841 caccgcgccc ggaccgcaaa gcgtcaccgg tggaacgcta aatgttttta cccgttgcag
    39901 attcagggta tcgaacgcct gaaagagcgc ggtctgcaat tcattttgca tatagcccct
    39961 ccgctttctc tcgcccgcta ctggcgatcg ccagcggggt cataaacaaa ctgtgctgcg
    40021 gtaaatgcac ctgtaacgcc gggaattgtt tgcgaaacag ttccgccacg cccggttgca
    40081 tacaagagcc gcccgccagc cataaatcag taatgccctg cccttcaata tgccgggcga
    40141 caatgtccgc cattttttcg tacactggtt tcaccgcggg ccaaatctct tcaccgtgac
    40201 cgcgcttgta ctgctctgcc tcttccagcg aaatacgacg atttccggcg agagtcagag
    40261 agatgtgatg tccgccggtc gcttcatccg ccgagtacgt caccttgccc tttttcacga
    40321 tggcaatacc agtagtgcca ccgccgatat ccactacacc agcgttgtcc agttgcagca
    40381 gatccgcgac tgcggttggc tcatccagta catggctcac ttccagtccg gcagattcca
    40441 gcacgttgat ggaaatacgc gggtccgtac caggaggaaa tgaggtcgcc gcatggctaa
    40501 aacggcgacc gaattgctgc tcaagggtgt cgagatggcg acgaacaatg gtgaccgcac
    40561 cgaagaaatc ccagacgatg ccgtcgcgga ccacatcggc ccagtcgagg cataccgcca
    40621 ccggcagacc gtcgcggtcg acaaccatcg acaccacatc gcaagtgccc agatccaccc
    40681 ccagccacag cggagattcc gtcgcggcgg gcgtctggtt acacagcgtt gccgccgttt
    40741 gcagacgtgg ggtgagccat tgttcatcgt gcgccatcgg ttactcctta aacaatgcga
    40801 aacgcatcga ctaatacaca gcgacgcaga cggacaaacg tccgcgcgct ggttacccct
    40861 tcaccggttg gcgtggtgat ggtcatcgtg gtccagc
//
LOCUS       DADXDL010000034        40647 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.034, whole genome shotgun sequence.
ACCESSION   DADXDL010000034 DADXDL010000000
VERSION     DADXDL010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40647)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40647)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40647
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.034"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..311
                     /gene="agaB"
                     /locus_tag="IRB70_002123"
     CDS             <1..311
                     /gene="agaB"
                     /locus_tag="IRB70_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HBC0632036.1"
                     /translation="YGFGIRFFTIEKTINVIGKAAPHQKIFLICRTPQTVRKLVEGGI
                     DLKDVNVGNMHFSEGKKQISSKVYVDDQDLTDLHFIKQRGVNVFIQDVPGDQKEQIPD
                     "
     gene            350..1153
                     /gene="agaC"
                     /locus_tag="IRB70_002124"
     CDS             350..1153
                     /gene="agaC"
                     /locus_tag="IRB70_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIC"
                     /protein_id="HBC0632037.1"
                     /translation="MHEITLLQGLSLAALVFFLGIDFWLEALFLFRPIIVCTLTGAIL
                     GDIQTGLITGGLTELAFAGLTPAGGVQPPNPIMAGLMTTVIAWSTGVDAKTAIGLGLP
                     FSLLMQYVILFFYSAFSLFMTKADKCAKEADTAAFSRLNWTTMLIVASAYAVIAFLCT
                     YLAQGAMQALVKAMPAWLTHGFEVAGGILPAVGFGLLLRVMFKAQYIPYLIAGFLFVC
                     YIQVSNLLPVAVLGAGFAVYEFFNAKSRQQAQPQSVVSNNEEEDYSNGI"
     gene            1143..1934
                     /gene="agaD"
                     /locus_tag="IRB70_002125"
     CDS             1143..1934
                     /gene="agaD"
                     /locus_tag="IRB70_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708938.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IID"
                     /protein_id="HBC0632038.1"
                     /translation="MGSEISKKDITRLGFRSSLLQASFNYERMQAGGFTWAMLPILKK
                     IYKDDKPGLSAAMKDNLEFINTHPNLVGFLMGLLISMEEKGENRDTIKGLKVALFGPI
                     AGIGDAIFWFTLLPIMAGICSSFASQGNLLGPILFFAVYLLIFFLRVGWTHVGYSVGV
                     KAIDKVRENSQMIARSATILGITVIGGLIASYVHINVVTSFAIDSTHSVALQQDFFDK
                     VFPNILPMAYTLLMYYFLRVKKAHPVLLIGVTFVLSIVCSAFGIL"
     gene            1935..2702
                     /locus_tag="IRB70_002126"
     CDS             1935..2702
                     /locus_tag="IRB70_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactosamine-6-phosphate isomerase"
                     /protein_id="HBC0632039.1"
                     /translation="MERGTASGGASLLKEFHPVQTLQQVENYTALSERASEYLLAVIR
                     SKPDAVICLATGATPLLTYHYLVEKIHQQQVDVSQLTFVKLDEWVDLPLTMPGTCETF
                     LQQHIVQPLGLREDQLISFRSEEINETECERVTNLIARKGGLDLCVLGLGKNGHLGLN
                     EPGESLQPACHISQLDARTQQHEMLKTAGRPVTRGITLGLKDILNTREVLLLVTGEGK
                     QDATERFLTAKVSTAIPASFLWLHNHFTCVIDEMCRR"
     gene            complement(2752..3615)
                     /gene="rsmI"
                     /locus_tag="IRB70_002127"
     CDS             complement(2752..3615)
                     /gene="rsmI"
                     /locus_tag="IRB70_002127"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBC0632040.1"
                     /translation="MKQHQSADNSQGQLYIVPTPIGNLADITQRALEVLQAVDLIAAE
                     DTRHTGLLLQHFGINARLFALHDHNEQQKAETLLAKLQEGQNIALVSDAGTPLINDPG
                     YHLVRTCREAGIRVVPLPGPCAAITALSAAGLPSDRFCYEGFLPAKSKGRRDALKAIE
                     AEPRTLIFYESTHRLLDSLEDIVAVLGESRYVVLARELTKTWETIHGAPVGELLAWVK
                     EDENRRKGEMVLIVEGHKAQEEDLPADALRTLALLQAELPLKKAAALAAEIHGVKKNA
                     LYKYALEQQGE"
     gene            3680..5716
                     /gene="lpoA"
                     /locus_tag="IRB70_002128"
     CDS             3680..5716
                     /gene="lpoA"
                     /locus_tag="IRB70_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708948.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein activator LpoA"
                     /protein_id="HBC0632041.1"
                     /translation="MVPSTFSRLKAARCLPVVLAALIFAGCGTHTPDQSTAYMQGTAQ
                     ADSAFYLQQMQQSSDDTRINWQLLAIRALVKEGKTGQAVELFNQLPQELNDSQRREKT
                     LLAAEIKLAQKDFAGAQNLLAKITPADLEQNQQARYWQAKIDASQGRPSIDLLRALIA
                     QEPLLGAKEKQQNIDVTWQALSSMTQEQANTLVINADENILQGWLDLQRIWFDNRNDP
                     DMMKAGIADWQKRYPNNPGAKMLPTQLVNVKAFKPASTNKIALLLPLNGQAAVFGRTI
                     QQGFEAAKNIGTQPVAAQVAAAPAADVAEQPQPQTVDGVASPAQASVSDLTGEQPAAQ
                     PVPVSAPVATTAAVSAPANPSAELKIYDTSSQPLSQILNQVQQDGASIVVGPLLKNNV
                     EELLKSNTPLNVLALNQPENIENRVNICYFALSPEDEARDAARHIRDQGKQAPLVLIP
                     RSSLGDRVANAFAQEWQKLGGSTVLQQKFGSTSELRAGVNGGSGIALTGSPITPRATT
                     DSGMTTNNPTLQTTPTDDQFTNNGGRVDAVYIVATPGEIAFIKPMIAMRNGSQSGATL
                     YASSRSAQGTAGPDFRLEMEGLQYSEIPMLAGGNLPLMQQALSAVNNDYSLARMYAMG
                     VDAWSLANHFSQMRQVQGFEINGNTGSLTANPDCVINRKLSWLQYQQGQVVPAS"
     gene            5674..6069
                     /locus_tag="IRB70_002129"
     CDS             5674..6069
                     /locus_tag="IRB70_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YraN family protein"
                     /protein_id="HBC0632042.1"
                     /translation="MATVPTRSGSPRQLTTKQTGDAWEAQARRWLESKGLRFVAANVN
                     ERGGEIDLIMREGRTTVFVEVRYRRSALYGGAAASVTRSKQHKLLQTARLWLARHNGS
                     FDTVDCRFDVVAFTGNEVEWIKDAFNDHS"
     gene            6089..6679
                     /gene="diaA"
                     /locus_tag="IRB70_002130"
     CDS             6089..6679
                     /gene="diaA"
                     /locus_tag="IRB70_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001483830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaA initiator-associating protein DiaA"
                     /protein_id="HBC0632043.1"
                     /translation="MQERIKACFTESIQTQIAAAEALPDAISRAAMTLVQSLLNGNKI
                     LCCGNGTSAANAQHFAASMINRFETERPSLPAIALNTDNVVLTAIANDRLHDEVYAKQ
                     VRALGHAGDVLLAISTRGNSRDIVKAVEAAVTRDMTIVALTGYDGGELAGLLGPQDVE
                     IRIPSHRSARIQEMHMLTVNCLCDLIDNTLFPHQDV"
     gene            6689..7264
                     /gene="yraP"
                     /locus_tag="IRB70_002131"
     CDS             6689..7264
                     /gene="yraP"
                     /locus_tag="IRB70_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divisome-associated lipoprotein YraP"
                     /protein_id="HBC0632044.1"
                     /translation="MKALSPIAVLISALLLQGCVAAAVVGTAAVGTKAATDPRSVGTQ
                     VDDGTLEVRVNSALSKDEQIKKEARINVTAYQGKVLLVGQSPNAELSARAKQIAMGVD
                     GANEVYNEIRQGQPIGLGEASNDTWITTKVRSQLLTSDLVKSSNVKVTTENGEVFLMG
                     LVTEREAKAAADIASRVSGVKRVTTAFTFIK"
     gene            complement(7386..8426)
                     /locus_tag="IRB70_002132"
     CDS             complement(7386..8426)
                     /locus_tag="IRB70_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBC0632045.1"
                     /translation="MTGQSSSQAATPIQWWKPALFFLVVIAGLWYVKWQPYYGKAFTA
                     AETHSIGKSILAQADANPWQAALDYAMIYFLAVWKAAVLGVLLGSLIQVLIPRDWLLR
                     TLGQSRFRGTLLGTLFSLPGMMCTCCAAPVAAGMRRQQVSMGGALAFWMGNPLLNPAT
                     LVFMGFVLGWGFAAIRLVAGLVMVLLIATLVQKWVRETPQTQAPVEIDIPEAQGGFFS
                     RWGRALWTLFWSTIPVYILAVLVLGAARVWLFPHADGAVDNSLMWVVAMAVAGCLFVI
                     PTAAEIPIVQTMMLAGMGTAPALALLMTLPAVSLPSLIMLRKAFPAKALWLTGAMVAV
                     SGVIVGGLALLA"
     gene            complement(8499..9134)
                     /locus_tag="IRB70_002133"
     CDS             complement(8499..9134)
                     /locus_tag="IRB70_002133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312060.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBC0632046.1"
                     /translation="MSQVLITGATGLVGGHLLRMLINEPKVNAIAAPTRRPLGDMSGV
                     FNPHDPQLTDALAQVTDPIDIVFCCLGTTRREAGSKEAFIHADYTLVVDTALTGRRLG
                     AQHMLVVSAMGANAHSPFFYNRVKGEMEEALIAQNWPKLTIARPSMLLGDRSKQRMNE
                     TLFAPLFRLLPGNWKSIDARDVARVMLAEAMRPEHEGVTILSSSELRKRAE"
     gene            9262..9780
                     /gene="yhbO"
                     /locus_tag="IRB70_002134"
     CDS             9262..9780
                     /gene="yhbO"
                     /locus_tag="IRB70_002134"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein/nucleic acid deglycase"
                     /protein_id="HBC0632047.1"
                     /translation="MSKKIAVLISDEFEDSEFTSPADEFRKAGHEVITIEKQAGKTVK
                     GKKGEASVAIDKSIDEVTPAEFDALLLPGGHSPDYLRGDNRFVTFTRDFVNSGKPVFA
                     ICHGPQLLISADVIRGRKLTAVKPIIIDVKNAGAEFYDQEVVVDKDQLVTSRTPDDLP
                     AFNREALRLLGA"
     gene            complement(9760..10203)
                     /locus_tag="IRB70_002135"
     CDS             complement(9760..10203)
                     /locus_tag="IRB70_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhbP family protein"
                     /protein_id="HBC0632048.1"
                     /translation="METLTAISRWLEKQHVVTWCVQQEGELWCANAFYLFDTQKVAFY
                     ILTEEKTRHAQMSGPQAAVAGTVNGQPKTVALIRGVQFKGEIRRLEGEESDLARQAYN
                     RRFPVARMLSAPVWEIRFDEIKFTDNTLGFGKKMIWLRNSGTEQA"
     gene            10254..10556
                     /gene="yhbQ"
                     /locus_tag="IRB70_002136"
     CDS             10254..10556
                     /gene="yhbQ"
                     /locus_tag="IRB70_002136"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708956.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage response exodeoxyribonuclease YhbQ"
                     /protein_id="HBC0632049.1"
                     /translation="MTPWFLYLIRTADNKLYTGITTDVERRYQQHQSGKGAKALRGKG
                     ELTLAFSAPVGDRSLALRAEYRVKQLTKRQKERLVAEGTGFAELLSSLQTPKIKSD"
     gene            complement(10543..11046)
                     /locus_tag="IRB70_002137"
     CDS             complement(10543..11046)
                     /locus_tag="IRB70_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBC0632050.1"
                     /translation="MLIRVEIPIDAPGIDALLRRSFESDAEAKLVHDLREDGFLTLGL
                     VATDDEGQVIGYVAFSPVDVQGEDLQWVGMAPLAVDEKYRGQGLARQLVYEGLDSLNE
                     FGYAAVVTLGDPALYSRFGFELAAHHDLRCRWPGTESAFQVHRLADDALNGVTGLVEY
                     HEHFNRF"
     gene            complement(11040..11564)
                     /locus_tag="IRB70_002138"
     CDS             complement(11040..11564)
                     /locus_tag="IRB70_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SCP2 domain-containing protein"
                     /protein_id="HBC0632051.1"
                     /translation="MLDKLRSRIVHLGPSLLSVPVKLTPFALKRQVLEQVLSWQFRQA
                     LDDGELEFLEGRWLSIHVRDIDLQWFTSVVNGKLVVSQNAQADVSFSADASDLLMIAA
                     RKQDPDTLFFQRRLVIEGDTELGLYVKNLMDAIELEQMPKALRMMLLQLADFVEAGMK
                     TAPETKQTSVGEPC"
     gene            11773..12768
                     /locus_tag="IRB70_002139"
     CDS             11773..12768
                     /locus_tag="IRB70_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017457364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBC0632052.1"
                     /translation="MELLCPAGNLPALKAAIENGADAVYIGLKDDTNARHFAGLNFTE
                     KKLQEAVSFVHQHRRKLHIAINTFAHPDGYARWQRAVDMAAQLGADALILADLAMLEY
                     AAERYPHIERHVSVQASATNEEAINFYHRHFDVARVVLPRVLSIHQVKQLARVTPIPL
                     EVFAFGSLCIMSEGRCYLSSYLTGESPNTVGACSPARFVRWQQTPQGLESRLNEVLID
                     RYQDGENAGYPTLCKGRYLVDGERYHALEEPTSLNTLELLPELMAANIASVKIEGRQR
                     SPAYVSQVAKVWRQAIDRCKADPQNFVPQSAWMETLGSMSEGTQTTLGAYHRKWQ"
     gene            12777..13655
                     /locus_tag="IRB70_002140"
     CDS             12777..13655
                     /locus_tag="IRB70_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417628.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBC0632053.1"
                     /translation="MKYSLGPVLWYWPKETLEEFYQQAAASSADVIYLGEAVCSKRRA
                     TKVGDWLEMAKSLAGSGKQIVLSTLALVQASSELGELKRYVENGEFLIEASDLGVVNM
                     CAERKLPFVAGHALNCYNAVTLKILLKQGMMRWCMPVELSRDWLVNLLNQCDELGIRN
                     QFEVEVLSYGHLPLAYSARCFTARSEDRPKDECETCCIKYPNGRNVLSQENQQVFVLN
                     GIQTMSGYVYNLGNELASMQGLVDVVRLSPQGTDTFAMLDAFRANENGAAPLPLTANS
                     DCNGYWRRLAGLELQA"
     gene            13736..14743
                     /locus_tag="IRB70_002141"
     CDS             13736..14743
                     /locus_tag="IRB70_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LLM class flavin-dependent oxidoreductase"
                     /protein_id="HBC0632054.1"
                     /translation="MTDKTIPFSLLDLAPIPEGSSAREAFSHSLDLARLAEKRGYHRY
                     WLAEHHNMTGIASAATSVLIGYLAANTTTLHLGSGGVMLPNHSPLVIAEQFGTLNTFY
                     PGRIDLGLGRAPGSDQRTMMALRRHMSGDIDNFPRDVAELVDWFDARDPNPHVRPVPG
                     YGEKIPVWLLGSSLYSAQLAAQLGLPFAFASHFAPDMLFQALHLYRSNFKPSARLEKP
                     YAMVCINIIAADSNRDAEFLFTSMQQAFVKLRRGETGQLPPPIQNMDQFWSPSEQYGV
                     QQALSMSLVGDKAKVRHGLQSILRETDADEIMVNGQIFDHQARLHSFELVMDVKEELL
                     G"
     gene            complement(14862..16106)
                     /gene="mtr"
                     /locus_tag="IRB70_002142"
     CDS             complement(14862..16106)
                     /gene="mtr"
                     /locus_tag="IRB70_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan permease"
                     /protein_id="HBC0632055.1"
                     /translation="MATLTTTQTSPSLLGGVVIIGGTIIGAGMFSLPVVMSGAWFFWS
                     MAALIFTWFCMLHSGLMILEANLNYRIGSSFDTITKDLLGKGWNVVNGISIAFVLYIL
                     TYAYISASGSILHHTFAEMSLNVPARAAGFGFALLVAFVVWLSTKAVSRMTAIVLGAK
                     VITFFLTFGSLLGHVQPATLFNVAESNASYAPYLLMTLPFCLASFGYHGNVPSLMKYY
                     GKDPKTIVKCLVYGTLMALALYTIWLLATMGNIPRPEFIGIAEKGGNIDVLVQALSGV
                     LNSRSLDLLLVVFSNFAVASSFLGVTLGLFDYLADLFGFDDSAMGRLKTALLTFAPPV
                     VGGLLFPNGFLYAIGYAGLAATIWAAIVPALLARASRKRFGSPKFRVWGGKPMIMLIL
                     VFGVGNALVHILSSFNLLPVYQ"
     gene            complement(16260..18149)
                     /gene="deaD"
                     /locus_tag="IRB70_002143"
     CDS             complement(16260..18149)
                     /gene="deaD"
                     /locus_tag="IRB70_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RNA helicase DeaD"
                     /protein_id="HBC0632056.1"
                     /translation="MAEFETTFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGR
                     DVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMR
                     GVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADE
                     MLRMGFIEDVETIMAQIPEGHQTALFSATMPEAIRRITRRFMKEPQEVRIQSSVTTRP
                     DISQSYWTVWGMRKNEALVRFLEAEDFDAAIIFVRTKNATLEVAEALERNGYNSAALN
                     GDMNQALREQTLERLKDGRLDILIATDVAARGLDVERISLVVNYDIPMDSESYVHRIG
                     RTGRAGRAGRALLFVENRERRLLRNIERTMKLTIPEVELPNAELLGKRRLEKFAAKVQ
                     QQLESSDLDQYRALLSKIQPTAEGEELDLETLAAALLKMAQGERTLIVPPDAPMRPKR
                     EFRDRDDRGPRDRNDRGPRGDREDRPRRERRDVGDMQLYRIEVGRDDGVEVRHIVGAI
                     ANEGDISSRYIGNIKLFASHSTIELPKGMPGEVLQHFTRTRILNKPMNMQLLGDAQPH
                     TGGERRGGGRGFGGERREGGRNFSGERREGGRGDGRRFSGERREGRAPRRDDSTGRRR
                     FGGDA"
     gene            complement(18142..18222)
                     /gene="yrbN"
                     /locus_tag="IRB70_002144"
     CDS             complement(18142..18222)
                     /gene="yrbN"
                     /locus_tag="IRB70_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YrbN"
                     /protein_id="HBC0632057.1"
                     /translation="MKIADQFHDELCRLAAINFEAHVLHG"
     gene            complement(18329..19213)
                     /gene="nlpI"
                     /locus_tag="IRB70_002145"
     CDS             complement(18329..19213)
                     /gene="nlpI"
                     /locus_tag="IRB70_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein NlpI"
                     /protein_id="HBC0632058.1"
                     /translation="MKPFLRWCFVATALTLAGCSNTSWRKSEVLAVPLQPTLQQEVIL
                     ARMEQILASRALTDDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYL
                     GIYLTQAGNFDAAYEAFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDD
                     PNDPFRSLWLYLAEQKLDEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNISEQTLMER
                     LKADATDNTSLAEHLSETNFYLGKYYLSLGDLDSATALFKLAVANNVHNFVEHRYALL
                     ELSLLGQDQDDLAESDQQ"
     gene            complement(19322..21457)
                     /gene="pnp"
                     /locus_tag="IRB70_002146"
     CDS             complement(19322..21457)
                     /gene="pnp"
                     /locus_tag="IRB70_002146"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312072.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBC0632059.1"
                     /translation="MLNPIVRKFQYGQHTVTLETGMMARQATAAVMVSMDDTAVFVTV
                     VGQKKAKPGQDFFPLTVNYQERTYAAGRIPGSFFRREGRPSEGETLIARLIDRPIRPL
                     FPEGFVNEVQVIATVVSVNPQVNPDIVAMIGASAALSLSGIPFNGPIGAARVGYINDQ
                     YVLNPTQDELKESKLDLVVAGTEAAVLMVESEAELLSEDQMLGAVVFGHEQQQVVIQN
                     INELVKEAGKPRWDWQPEPVNEALNARVAALAEARLSDAYRITDKQERYAQVDVIKSE
                     TIATLLAEDETLDENELGEILHAIEKNVVRSRVLAGEPRIDGREKDMIRGLDVRTGVL
                     PRTHGSALFTRGETQALVTATLGTARDAQVLDELMGERTDTFLFHYNFPPYSVGETGM
                     VGSPKRREIGHGRLAKRGVLAVMPDMDKFPYTVRVVSEITESNGSSSMASVCGASLAL
                     MDAGVPIKAAVAGIAMGLVKEGDNYVVLSDILGDEDHLGDMDFKVAGSRDGISALQMD
                     IKIEGITKEIMQVALNQAKGARLHILGVMEQAINAPRGDISEFAPRIHTIKINPDKIK
                     DVIGKGGSVIRALTEETGTTIEIEDDGTVKIAATDGEKAKHAIRRIEEITAEIEVGRV
                     YNGKVTRIVDFGAFVAIGGGKEGLVHISQIADKRVEKVTDYLQMGQEVPVKVLEVDRQ
                     GRIRLSIKEATEQSQPAAAPEAPAAEQGE"
     gene            complement(21704..21973)
                     /gene="rpsO"
                     /locus_tag="IRB70_002147"
     CDS             complement(21704..21973)
                     /gene="rpsO"
                     /locus_tag="IRB70_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBC0632060.1"
                     /translation="MSLSTEATAKIVSEFGRDANDTGSTEVQVALLTAQINHLQGHFA
                     EHKKDHHSRRGLLRMVSQRRKLLDYLKRKDVARYTQLIERLGLRR"
     gene            complement(22122..23066)
                     /gene="truB"
                     /locus_tag="IRB70_002148"
     CDS             complement(22122..23066)
                     /gene="truB"
                     /locus_tag="IRB70_002148"
                     /EC_number="5.4.99.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBC0632061.1"
                     /translation="MSRPRRRGRDINGVLLLDKPQGMSSNDALQKVKRIYNANRAGHT
                     GALDPLATGMLPICLGEATKFSQYLLDSDKRYRVIARLGQRTDTSDADGQIVEERPVT
                     FSAEQLAAALDTFRGDIEQIPSMYSALKYQGKKLYEYARQGIEVPREARPITVYELLF
                     IRHEGNELELEIHCSKGTYIRTIIDDLGEKLGCGAHVIYLRRLAVSKYPVERMVTLEH
                     LRELVEQAEQQDIPAAELLDPLLMPMDSPASDYPVVNLPLTSSVYFKNGNPVRTSGAP
                     LEGLVRVTEGENGKFIGMGEIDDEGRVAPRRLVVEYPA"
     gene            complement(23066..23467)
                     /gene="rbfA"
                     /locus_tag="IRB70_002149"
     CDS             complement(23066..23467)
                     /gene="rbfA"
                     /locus_tag="IRB70_002149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001712908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBC0632062.1"
                     /translation="MAKEFGRPQRVAQEMQKEIALILQREIKDPRLGMMTTVSGVEMS
                     RDLAYAKVYVTFLNDKDEDAVKAGIKALQEASGFIRSLLGKAMRLRIVPELTFFYDNS
                     LVEGMRMSNLVTSVVKHDEERRVNPDDSKED"
     gene            complement(23631..26303)
                     /gene="infB"
                     /locus_tag="IRB70_002150"
     CDS             complement(23631..26303)
                     /gene="infB"
                     /locus_tag="IRB70_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBC0632063.1"
                     /translation="MTDVTIKTLAAERQTSVERLVQQFADAGIRKSADDSVSAQEKQT
                     LIDHLNQKNSGPDKLTLQRKTRSTLNIPGTGGKSKSVQIEVRKKRTFVKRDPQEAERL
                     AAEEQAQREAEEQARREAEESAKREAQQKAEREAAEQAKREAAEQAKREAAEKDKVSN
                     QQDDMTKNAQAEKARREQEAAELKRKAEEEARRKLEEEARRVAEEARRMAEENKWTDN
                     AEPTEDSSDYHVTTSQHARQAEDESDREVEGGRGRGRNAKAARPKKGNKHAESKADRE
                     EARAAVRGGKGGKRKGSSLQQGFQKPAQAVNRDVVIGETITVGELANKMAVKGSQVIK
                     AMMKLGAMATINQVIDQETAQLVAEEMGHKVILRRENELEEAVMSDRDTGAAAEPRAP
                     VVTIMGHVDHGKTSLLDYIRSTKVASGEAGGITQHIGAYHVETENGMITFLDTPGHAA
                     FTSMRARGAQATDIVVLVVAADDGVMPQTIEAIQHAKAAQVPVVVAVNKIDKPEADPD
                     RVKNELSQYGILPEEWGGESQFVHVSAKAGTGIDELLDAILLQAEVLELKAVRKGMAS
                     GAVIESFLDKGRGPVATVLVREGTLHKGDIVLCGFEYGRVRAMRNELGQEVLEAGPSI
                     PVEILGLSGVPAAGDEVTVVRDEKKAREVALYRQGKFREVKLARQQKSKLENMFANMT
                     EGEVHEVNIVLKADVQGSVEAISDSLLKLSTDEVKVKIIGSGVGGITETDATLAAASN
                     AILVGFNVRADASARKVIEAESLDLRYYSVIYNLIDEVKAAMSGMLSPELKQQIIGLA
                     EVRDVFKSPKFGAIAGCMVTEGVVKRHNPIRVLRDNVVIYEGELESLRRFKDDVNEVR
                     NGMECGIGVKNYNDVRTGDVIEVFEIIEIQRTIA"
     gene            complement(26328..27815)
                     /gene="nusA"
                     /locus_tag="IRB70_002151"
     CDS             complement(26328..27815)
                     /gene="nusA"
                     /locus_tag="IRB70_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005131833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBC0632064.1"
                     /translation="MNKEILAVVEAVSNEKALPREKIFEALESALATATKKKYEQEID
                     VRVQIDRKSGDFDTFRRWLVVDEVTQPTKEITLEAARYEDESLNLGDYVEDQIESVTF
                     DRITTQTAKQVIVQKVREAERAMVVDQFREHEGEIITGVVKKVNRDNISLDLGNNAEA
                     VILREDMLPRENFRPGDRVRGVLYSVRPEARGAQLFVTRSKPEMLIELFRIEVPEIGE
                     EVIEIKAAARDPGSRAKIAVKTNDKRIDPVGACVGMRGARVQAVSTELGGERIDIVLW
                     DDNPAQFVINAMAPADVASIVVDEDKHTMDIAVEAGNLAQAIGRNGQNVRLASQLSGW
                     ELNVMTVDDLQAKHQAEAHAAIDTFTKYLDIDEDFATVLVEEGFSTLEELAYVPMKEL
                     LEIEGLDEPTVEALRERAKNALATIAQAQEESLGDNKPADDLLNLEGIDRDLAFKLAA
                     RGVCTLEDLAEQGIDDLADIEGLTDEKAGALIMAARNICWFGDEA"
     gene            complement(27843..28295)
                     /gene="rimP"
                     /locus_tag="IRB70_002152"
     CDS             complement(27843..28295)
                     /gene="rimP"
                     /locus_tag="IRB70_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBC0632065.1"
                     /translation="MSTLEQKLTEMITAPVEALGFELVGIEFIRGRTSTLRIYIDSED
                     GINVDDCADVSHQVSAVLDVEDPITVAYNLEVSSPGLDRPLFTAEHYARFVGEEVTLV
                     LRMAVQNRRKWQGVIKAVDGEMITVTVEGKDEVFALSNIQKANLVPHF"
     gene            complement(28502..28578)
                     /locus_tag="IRB70_002153"
     tRNA            complement(28502..28578)
                     /locus_tag="IRB70_002153"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(28542..28544),aa:Met,seq:cat)
     gene            28926..30269
                     /gene="argG"
                     /locus_tag="IRB70_002154"
     CDS             28926..30269
                     /gene="argG"
                     /locus_tag="IRB70_002154"
                     /EC_number="6.3.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="argininosuccinate synthase"
                     /protein_id="HBC0632066.1"
                     /translation="MTTILKHLPVGQRIGIAFSGGLDTSAALLWMRQKGAVPYAYTAN
                     LGQPDEEDYDAIPRRAMEYGAENARLIDCRKQLVAEGIAAIQCGAFHNTTGGLTYFNT
                     TPLGRAVTGTMLVAAMKEDGVNIWGDGSTYKGNDIERFYRYGLLTNAELQIYKPWLDT
                     DFIDELGGRHEMSEFMIACGFDYKMSVEKAYSTDSNMLGATHEAKDLEYLNSSVKIVN
                     PIMGVKFWDESVKIPAEEVTVRFEQGHPVALNGKTFSDDVEMLLEANRIGGRHGLGMS
                     DQIENRIIEAKSRGIYEAPGMALLHIAYERLLTGIHNEDTIEQYHAHGRQLGRLLYQG
                     RWFDSQALMLRDSLQRWVASQITGEVTLELRRGNDYSILNTVSENLTYKPERLTMEKG
                     DSVFSPDDRIGQLTMRNLDITDTREKLFGYAKTGLLSSSAASGVPQVENLENKGQ"
     gene            complement(30277..31902)
                     /locus_tag="IRB70_002155"
     CDS             complement(30277..31902)
                     /locus_tag="IRB70_002155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417641.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
                     /protein_id="HBC0632067.1"
                     /translation="MTVFNKFVRSFKSHWLLYLCVIVFGITNLVASSGAHMVQRLLFF
                     VLTILVVKRISSLPLRLLVAAPFVLLTAADMSISLYSWCTFGTTFNDGFAISVLQSDP
                     DEVVKMLGMYIPYLCAFSFLSLLFLAVIIKYDVSLPTKKVTGILLLIVISGSLFSACQ
                     FAYKDAKNKKAFSPYILASRFATYTPFFNLNYFALAAKEHQRLLSIANTVPYFQLSVR
                     DTGIDTYVLIVGESVRVDNMSLYGYTRSTTPQVEAQRKQIKLFNQAISGAPYTALSVP
                     LSLTADSVLSHDIHNYPDNIINMANQAGFQTFWLSSQSAFRQNGTAVTSIAMRAMETV
                     YVRGFDELLLPHLSQALQQKTQQKKLIVLHLNGSHEPACSAYPQSSAVFQPQDDQDAC
                     YDNSIHYTDSLLGQVFELLKDRRASVMYFADHGLERDPTKKNVYFHGGREASQQAYHV
                     PMFIWYSPVLGDGVDRTTENDIFSTAYNNYLINAWMGVTKPEQPQTLEEVIAHYKGDS
                     RVVDANHDVFDFVMLRKEFTEDKQGNPTPEGQG"
     gene            complement(32359..32445)
                     /locus_tag="IRB70_002156"
     tRNA            complement(32359..32445)
                     /locus_tag="IRB70_002156"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32409..32411),aa:Leu,seq:gag)
     gene            complement(32460..32792)
                     /gene="secG"
                     /locus_tag="IRB70_002157"
     CDS             complement(32460..32792)
                     /gene="secG"
                     /locus_tag="IRB70_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBC0632068.1"
                     /translation="MYEALLVVFLIVAIGLVGLIMLQQGKGADMGASFGAGASATLFG
                     SSGSGNFMTRMTALLATLFFIISLVLGNINSNKTNKGSEWENLSAPAKTEQTQPAAPA
                     KPTSDIPN"
     gene            complement(33020..34357)
                     /gene="glmM"
                     /locus_tag="IRB70_002158"
     CDS             complement(33020..34357)
                     /gene="glmM"
                     /locus_tag="IRB70_002158"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBC0632069.1"
                     /translation="MSNRKYFGTDGIRGRVGDAPITPDFVLKLGWAAGKVLARHGSRK
                     IIIGKDTRISGYMLESALEAGLAAAGLSALFTGPMPTPAVAYLTRTFRAEAGIVISAS
                     HNPFYDNGIKFFSIDGTKLPDAVEEAIEAEMEKEISCVDSAELGKASRIVDAAGRYIE
                     FCKATFPNELSLSELKIVVDCANGATYHIAPNVLRELGANVIAIGCEPNGVNINAEVG
                     ATDVRALQARVLAEKADLGIAFDGDGDRVIMVDHEGNKVDGDQIMYIIAREGLRQGQL
                     RGGAVGTLMSNMGLELALKQLGIPFARAKVGDRYVLEKMQEKGWRIGAENSGHVILLD
                     KTTTGDGIVAGLQVLAAMARNHMSLHDLCSGMKMFPQILVNVRYTAGSGDPLEHESVK
                     AVTAEVEAALGSRGRVLLRKSGTEPLIRVMVEGEDEAQVTEFAHRIADAVKAV"
     gene            complement(34350..35198)
                     /gene="folP"
                     /locus_tag="IRB70_002159"
     CDS             complement(34350..35198)
                     /gene="folP"
                     /locus_tag="IRB70_002159"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312083.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBC0632070.1"
                     /translation="MKLFAQGTSLDLSHPHVMGILNVTPDSFSDGGTHNSLIDAVKHA
                     NLMINAGATIIDVGGESTRPGAAEVSVEEELQRVIPVVEAIAQRFEVWISVDTSKPEV
                     IRESAKVGAHIINDIRSLSEPGALEAAAETGLPVCLMHMQGNPKTMQEAPKYDDVFAE
                     VNRYFIEQIARCEQAGIAKEKLLLDPGFGFGKNLSHNYSLLARLAEFHHFNLPLLVGM
                     SRKSMIGQLLNVGPSERLSGSLACAVIAAMQGAHIIRVHDVKETVEAMRVVEATLSAK
                     ENKRYE"
     gene            complement(35288..37222)
                     /gene="ftsH"
                     /locus_tag="IRB70_002160"
     CDS             complement(35288..37222)
                     /gene="ftsH"
                     /locus_tag="IRB70_002160"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBC0632071.1"
                     /translation="MAKNLILWLVIAVVLMSVFQSFGPSESNGRKVDYSTFLQEVNND
                     QVREARINGREINVTKKDSNRYTTYIPVQDPKLLDNLLTKNVKVVGEPPEEPSLLASI
                     FISWFPMLLLIGVWIFFMRQMQGGGGKGAMSFGKSKARMLTEDQIKTTFADVAGCDEA
                     KEEVAELVEYLREPSRFQKLGGKIPKGVLMVGPPGTGKTLLAKAIAGEAKVPFFTISG
                     SDFVEMFVGVGASRVRDMFEQAKKAAPCIIFIDEIDAVGRQRGAGLGGGHDEREQTLN
                     QMLVEMDGFEGNEGIIVIAATNRPDVLDPALLRPGRFDRQVVVGLPDVRGREQILKVH
                     MRRVPLAPDIDAAIIARGTPGFSGADLANLVNEAALFAARGNKRVVSMVEFEKAKDKI
                     MMGAERRSMVMTEAQKESTAYHEAGHAIIGRLVPEHDPVHKVTIIPRGRALGVTFFLP
                     EGDAISASRQKLESQISTLYGGRLAEEIIYGPEHVSTGASNDIKVATNLARNMVTQWG
                     FSEKLGPLLYAEEEGEVFLGRSVAKAKHMSDETARIIDQEVKALIERNYNRARQLLTD
                     NMDILHAMKDALMKYETIDAPQIDDLMARRDVRPPAGWEEPGASNNSGDNGSPKAPRP
                     VDEPRTPNPGNTMSEQLGDK"
     gene            complement(37322..37951)
                     /gene="rlmE"
                     /locus_tag="IRB70_002161"
     CDS             complement(37322..37951)
                     /gene="rlmE"
                     /locus_tag="IRB70_002161"
                     /EC_number="2.1.1.166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uridine(2552)-2'-O)-methyltransferase
                     RlmE"
                     /protein_id="HBC0632072.1"
                     /translation="MTGKKRSASSSRWLQEHFSDKYVQQAQKKGLRSRAWFKLDEIQQ
                     SDKLFKPGMTVVDLGAAPGGWSQYVVTQIGGKGRIIACDLLPMDPIVGVDFLQGDFRD
                     ELVMKALLERVGDSKVQVVMSDMAPNMSGTPAVDIPRAMYLVELALEMCRDVLAPGGS
                     FVVKVFQGEGFDEYLREIRSLFTKVKVRKPDSSRARSREVYIVATGRKP"
     gene            38077..38370
                     /gene="yhbY"
                     /locus_tag="IRB70_002162"
     CDS             38077..38370
                     /gene="yhbY"
                     /locus_tag="IRB70_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014833438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBC0632073.1"
                     /translation="MNLSTKQKQHLKGLAHPLKPVVLLGSNGLTEGVLAEIEQALEHH
                     ELIKVKIATEDRETKTLIVEAIVRETGACNVQVIGKTLVLYRPTKERKISLPR"
     gene            complement(38526..39002)
                     /gene="greA"
                     /locus_tag="IRB70_002163"
     CDS             complement(38526..39002)
                     /gene="greA"
                     /locus_tag="IRB70_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006178768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBC0632074.1"
                     /translation="MQAIPMTLRGAEKLREELDFLKSVRRPEIIAAIAEAREHGDLKE
                     NAEYHAAREQQGFCEGRIKDIEAKLSNAQVIDVTKMPNNGRVIFGATVTVLNLDSDEE
                     QTYRIVGDDEADFKQNLISVNSPIARGLIGKEEDDVVVIKTPGGEVEFEVIKVEYL"
     gene            39251..>40647
                     /gene="dacB"
                     /locus_tag="IRB70_002164"
     CDS             39251..>40647
                     /gene="dacB"
                     /locus_tag="IRB70_002164"
                     /EC_number="3.4.16.4"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001212660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase"
                     /protein_id="HBC0632075.1"
                     /translation="MRFSRFIIGLTSCIAFSVQAANVDEYITQLPAGANLALMVQKVG
                     ASAPAIDYHSQQMALPASTQKVITALAALIQLGPDFRFTTTLETKGNVENGVLKGDLV
                     ARFGADPTLKRQDIRNMVATLKKSGVNQIDGNVLIDTSIFASHDKAPGWPWNDMTQCF
                     SAPPAAAIVDRNCFSVSLYSAPKPGDMAFIRVASYYPVTMFSQVRTLPRGSAEAQYCE
                     LDVVPGDLNRFTLTGCLPQRSEPLPLAFAVQDGASYAGAILKDELKQAGITWSGTLLR
                     QTQVNEPGTVVASKQSAPLHDLLKIMLKKSDNMIADTVFRMIGHARFNVPGTWRAGSD
                     AVRQILRQQAGVDIGNTIIADGSGLSRHNLIAPATMMQVLQYIAQHDNELNFISMLPL
                     AGYDGSLQYRAGLHQAGVDGKVSAKTGSLQGVYNLAGFITTASGQRMAFVQYLSGYAV
                     EPADQRNRRIPLVRF"
BASE COUNT         9826 a        11020 c        10061 g         9740 t
ORIGIN      
        1 cctacggctt tggcattcgt ttctttacta tcgaaaaaac cattaacgtc atcggcaaag
       61 ctgcaccgca tcagaagatc ttcctgattt gccgtacgcc acaaacggta cgtaaattgg
      121 tagaaggtgg tattgacctg aaagatgtca acgtcggcaa tatgcatttc tcggaaggga
      181 aaaagcaaat cagcagtaaa gtttatgtcg atgaccagga tctcacggac ttacatttta
      241 ttaaacaacg tggcgtgaat gttttcattc aggacgtccc tggcgatcaa aaagaacaaa
      301 tccctgacta aatctaaaat cgccttaata ttggtttgag gtaataaaaa tgcatgaaat
      361 aaccctactc cagggattat ccctggcggc gttagttttc tttctgggga ttgatttttg
      421 gctggaagcc ttatttttat tccgcccgat aatcgtttgt acccttacag gtgctattct
      481 cggtgatatt cagactggct taattaccgg tggcctgaca gagttggctt tcgccggatt
      541 aacccctgca ggtggtgttc agccgcccaa ccctattatg gcgggtctga tgaccactgt
      601 cattgcatgg tctacgggcg ttgatgccaa aacggcaatt ggtcttggcc tgccgtttag
      661 tttgttaatg cagtacgtca ttctgttctt ctattccgct ttctcattat ttatgaccaa
      721 agccgataaa tgcgcaaaag aggcggatac ggcagcattt tcccgactta actggacaac
      781 gatgctcatc gtcgcttcag cgtatgcggt gattgctttc ctctgtactt acctggcaca
      841 aggggcgatg caggcgctgg tgaaagcgat gcccgcttgg ctgacccacg gctttgaagt
      901 ggctggcggt attctgcctg ccgttggttt tggcttgctg ctgcgcgtga tgttcaaagc
      961 gcaatatatc ccttacctga tcgccggttt cctgttcgtt tgctacatcc aggtcagcaa
     1021 cctgttgccg gttgccgtgc tgggtgcagg ctttgcggtg tatgagtttt tcaatgcgaa
     1081 atcccggcag caagcgcaac cgcagtccgt tgtcagtaat aatgaagaag aggactacag
     1141 caatgggatc tgaaatcagt aaaaaagata tcacccgtct gggctttcgt tcgtcactgc
     1201 tgcaagcgag ctttaactac gaaaggatgc aggcgggcgg ttttacctgg gcgatgttgc
     1261 cgatcctgaa aaagatttat aaggacgaca aaccgggcct aagcgcggcg atgaaagata
     1321 acctcgaatt tattaatacc cacccgaatc tggtcggatt cctgatgggg ttattaattt
     1381 cgatggaaga aaaaggagaa aaccgcgaca ccattaaagg cctcaaagtg gcactgtttg
     1441 gcccaatcgc cgggattggc gatgcgattt tctggtttac cttattgccg attatggcgg
     1501 gaatttgctc atcatttgcc agccagggaa acttgctggg gccgattcta tttttcgccg
     1561 tttacctgct tatcttcttc ctgcgcgtcg gctggaccca cgtcggttat tcagtcggcg
     1621 tgaaggctat tgataaagtg cgagagaact cgcagatgat tgctcgttcg gcaaccatcc
     1681 tcgggatcac ggtaatcggc gggctgatcg cttcgtatgt gcatattaac gtggtgacat
     1741 cgtttgccat cgacagtacc cacagcgtcg cactgcagca ggatttcttc gataaagtct
     1801 tcccgaacat tttaccgatg gcctacaccc tgctgatgta ttacttcctg cgggtgaaaa
     1861 aagcgcatcc ggtgctgtta atcggcgtga cttttgtgct ctctattgtt tgttccgcat
     1921 tcggcatttt gtaaatggaa cgaggcactg cgtctggcgg tgcctcttta cttaaggaat
     1981 ttcatcctgt gcaaaccctt caacaagttg aaaactatac ggcgttaagt gaacgtgcca
     2041 gcgaatattt attggccgtg atccgtagta aaccggatgc cgtgatttgc ctggcgaccg
     2101 gagccacgcc attactgacg tatcattatc tggtagaaaa aatccaccag cagcaggttg
     2161 atgtcagcca gctcaccttc gtgaagctcg acgaatgggt ggatctgcca ttaacaatgc
     2221 ctggcacctg cgaaactttc ctacaacagc atatcgtgca gccgctgggg ctgcgtgaag
     2281 accagctcat cagctttcgc tctgaagaga taaatgagac agagtgcgaa cgggtaacga
     2341 acctgattgc gcgcaaaggc ggtctggatt tatgcgttct cggattgggg aaaaacggtc
     2401 atcttgggct gaacgaaccg ggagaaagcc tgcaaccggc ctgccatatc agtcaacttg
     2461 atgccagaac acagcaacat gagatgttaa aaaccgcggg ccgtcccgtg actcgtggga
     2521 tcaccttagg cctgaaggat attctcaata cccgcgaagt tttgctactg gtgactggcg
     2581 aaggaaagca ggatgcgaca gaacgttttc tcacggctaa agtctctacc gctatcccgg
     2641 cttcgttttt atggctgcat aaccatttca catgcgtgat tgatgaaatg tgtcgtcgtt
     2701 aactcgcctg gtaaaggcgt tgtagcgcta ttcctgctgc aacgcctgta atcactctcc
     2761 ctgctgctcc agtgcatact tatacagcgc atttttcttc acgccgtgaa tttctgctgc
     2821 cagcgccgcc gcttttttca gtggcagttc tgcctgcaac agcgccagcg tgcgcagggc
     2881 atcggcgggt aagtcttctt cctgtgcttt atggccttcg acaatcagta ccatttcgcc
     2941 tttgcgacgg ttttcatctt ctttgaccca cgccagcagc tcgccaacgg gcgcgccgtg
     3001 aatggtttcc caggttttgg tcagctcacg cgccagaacg acgtagcggg attcgcctaa
     3061 taccgcaacg atatcttcca ggctatctaa cagacggtgg gtagattcat aaaaaatcag
     3121 cgtgcgcggc tccgcttcaa tggcttttag cgcatcacgg cggccttttg atttggcagg
     3181 taaaaagcct tcataacaaa aacgatcgga tggtaaaccc gcggcgctta acgcagtgat
     3241 agcagcacac ggcccgggta gcggcaccac gcgaatcccc gcttcacggc aggtacgcac
     3301 cagatggtag ccaggatcgt taattagcgg cgttccggca tcggaaacca gcgcaatgtt
     3361 ttgcccctct tgcagcttcg ccagcagcgt ttcggctttt tgttgttcgt tatggtcgtg
     3421 cagcgcaaac aaccgagcat taatcccaaa atgttgcagc aataaaccgg tgtgacgcgt
     3481 atcctcggcg gcaatcagat caacggcctg taatacctcc aacgcacgct gggtgatatc
     3541 cgccagattg ccgattggcg tcggtacaat gtaaagctgg ccctgagaat tatccgccga
     3601 ttggtgttgt ttcattgtgt cgtccgtatt gccgatttaa tattgagcat tgcgtaaaaa
     3661 aaatatcact ggatacatta tggtaccctc aacattttct cgtttgaaag ccgcgcgttg
     3721 tctgcctgtt gttctggcag ccctgatttt cgccggttgt ggcacccata ctcccgatca
     3781 gtccactgct tatatgcagg gcacggcgca ggctgattct gccttttacc tgcaacagat
     3841 gcagcaaagt tctgatgata ccaggatcaa ctggcaatta ctcgccattc gtgcactggt
     3901 gaaagaaggt aaaaccggac aggcggtgga gttgtttaac caactaccgc aagaactgaa
     3961 cgattctcag cgtcgcgaga aaacactgct ggcggcagag attaaactgg cgcagaaaga
     4021 ttttgctggc gcgcaaaact tgctggcgaa aatcacacct gcagatttag aacaaaacca
     4081 gcaagcgcgt tactggcagg caaaaatcga tgccagccag gggcgtcctt ccattgattt
     4141 actgcgcgcg ttaattgctc aggaaccgct gctcggcgcg aaagaaaagc agcagaatat
     4201 tgacgtcacc tggcaggcgc tctcctccat gactcaggaa caggcgaata cgctggtgat
     4261 caatgccgac gaaaatattc tgcaaggctg gttggatctg cagcgcatct ggtttgataa
     4321 ccgtaacgat cccgacatga tgaaagccgg gatcgccgac tggcagaaac gttatccgaa
     4381 caacccgggc gcgaaaatgc tgccaacgca gttggttaac gtaaaagcgt ttaaaccagc
     4441 atcgaccaac aaaatcgccc tgctgttgcc actgaatggc caggcagcgg tatttggtcg
     4501 cactattcag caaggctttg aagcggcgaa aaatatcggc actcagccag tggcggccca
     4561 ggtagctgcc gcacctgccg cagacgtagc agaacaacct cagccgcaaa ccgtggatgg
     4621 cgttgccagc ccggcacaag cctcggttag cgatctgacc ggtgaacaac ctgcggccca
     4681 gccggtgcct gtaagcgccc cggtggcaac caccgcagcg gtaagcgcac ccgcgaatcc
     4741 atccgcagag ctgaaaatct acgatacatc atcacaacca cttagccaga tcctcaacca
     4801 ggttcaacag gatggtgcga gtattgtggt cggtccgttg ctgaaaaata acgttgaaga
     4861 gttgctgaag agcaacactc cgctgaacgt gctggcactg aaccagccgg agaatatcga
     4921 aaaccgcgtc aatatttgtt acttcgcgct ttcaccggaa gacgaagcgc gcgatgcagc
     4981 gcgtcatatt cgtgaccagg gtaaacaagc gccgctggtg ctgatcccac gcagttcatt
     5041 gggcgatcgc gtagccaatg cgtttgcgca agagtggcag aaactgggtg gcagcaccgt
     5101 tctgcaacaa aaatttggtt ccaccagcga attacgcgcg ggtgttaacg gcggttctgg
     5161 tattgcttta acgggtagcc cgattactcc cagagcgaca accgactccg gcatgacgac
     5221 caacaatcca acgctgcaaa ccacgccaac cgatgaccag ttcaccaata atggcggtcg
     5281 tgtcgatgcg gtgtacattg tggcaacgcc gggtgaaatc gcttttatca aaccaatgat
     5341 cgccatgcgt aacggtagcc agagcggtgc aacgctgtac gccagctccc gcagtgcgca
     5401 agggaccgcg ggcccggatt tccgcctgga gatggaaggc ttgcagtaca gcgaaatccc
     5461 gatgctggca ggcggtaatc tgccgttaat gcagcaggcg ctcagcgcgg tgaacaacga
     5521 ttattcgctg gctcgcatgt atgcgatggg cgtcgatgcc tggtcgttgg caaatcattt
     5581 ctcacaaatg cgccaggttc agggttttga aatcaacggt aataccggaa gtctgacggc
     5641 taacccggat tgcgtaatta acaggaagtt atcatggcta cagtaccaac aaggtcaggt
     5701 agtccccgcc agttaaccac taaacagacc ggcgatgcgt gggaagcaca agcgcgtcgc
     5761 tggctggaga gcaaaggact gcggtttgtc gccgctaacg tgaacgagcg tggcggcgag
     5821 atcgatctga taatgcgtga aggccggacc accgtttttg tcgaggtgcg ttaccgccgc
     5881 tctgcgcttt atggcggcgc ggcagccagt gtgacccgca gcaaacaaca caaattatta
     5941 cagactgccc gcttgtggct cgcgcgtcat aatgggagtt ttgatactgt ggattgccgg
     6001 ttcgatgtgg tagccttcac cgggaatgag gttgagtgga ttaaggatgc ctttaatgac
     6061 cactcataat taaggtttaa ggattagcgt gcaagaaaga attaaagctt gcttcactga
     6121 aagcattcaa actcaaattg cggcggcaga ggcgcttccg gatgccatct cgcgtgcagc
     6181 tatgacgctg gttcagtctc tgctcaatgg caacaaaatc ctctgttgtg gtaatggaac
     6241 ttccgctgcc aatgcacagc attttgctgc cagcatgatc aaccgtttcg aaacggagcg
     6301 gcccagctta cctgccattg cactaaatac tgataatgtt gtcttaacgg caattgccaa
     6361 cgatcgctta catgatgaag tgtatgcaaa acaggtgcgg gcgctgggtc atgcgggaga
     6421 tgtattgtta gccatttcca cccgtggcaa cagccgcgat attgtaaaag cggtagaagc
     6481 tgccgttacg cgtgatatga ccattgtggc attaaccggc tatgacggcg gtgaacttgc
     6541 aggtttgtta gggccacagg atgtggagat ccgcattcct tcgcatcgta gtgctcgcat
     6601 tcaggagatg catatgctga cggtaaattg cctgtgcgat ctgatcgata acacgctttt
     6661 ccctcaccag gatgtttaag gagaatacat gaaggcatta tcgccaatcg cagtccttat
     6721 ttccgcgctg ctgttgcaag gttgtgttgc cgctgccgta gtgggtactg ctgctgtggg
     6781 taccaaagcc gcaactgacc cacgcagtgt cggcacccag gtggacgatg gtaccctgga
     6841 agtgcgcgtg aacagcgcat tgtcgaaaga cgaacaaatt aagaaagaag cgcgcattaa
     6901 tgtaacggcc tatcagggca aagtgctgct agttgggcag tcaccaaacg ctgaactttc
     6961 ggctcgcgct aaacaaattg cgatgggcgt agacggtgcc aacgaagtgt ataacgagat
     7021 tcgtcagggc cagccgattg gtctgggcga agcgtctaac gatacgtgga tcaccaccaa
     7081 agtgcgttcg cagctcttaa ccagcgatct ggtgaaatcg tccaacgtga aagtgaccac
     7141 cgaaaacggt gaagtgttcc tgatggggct ggtgactgaa cgtgaagcga aagcggcggc
     7201 agatattgcc agccgggtaa gcggcgtgaa gcgggtaacc acggcgttta cgtttattaa
     7261 ataagccatt gatcggtcgt tgaagtaaat attcacacct tagccgacct gttcccctca
     7321 ccctaaccct ctccccaaag gggagagggg accgtccagt gctgtattca ggagcatcca
     7381 acatcttagg ccaacagcgc caacccgccg acaatcacac cagacactgc caccatcgcc
     7441 cctgtcagcc ataaggcttt cgccgggaac gctttgcgca gcataatcag tgacggcaaa
     7501 ctcaccgccg ggagcgtcat caacaatgcc agcgccggag cggttcccat gcctgccagc
     7561 atcatcgttt gtacaatcgg aatttctgct gccgtgggaa tgacaaacaa gcatcctgcc
     7621 accgccatcg ccaccaccca catcaggctg ttatcgacag caccatcggc atgggggaat
     7681 aaccagacgc gagcggcacc caacaccagt actgcaagga tgtaaaccgg gatcgtactc
     7741 cagaaaagcg tccatagcgc cctgccccag cggctaaaaa atcctccctg tgcttccggt
     7801 atgtcaattt cgaccggtgc ctgcgtttgc ggtgtttcac gcacccattt ttgcaccagc
     7861 gtcgcaatca gcaacaccat caccagcccc gccaccagac gaatcgcggc aaagccccag
     7921 ccaaggacaa atcccatgaa taccagcgtc gccgggttta acaacggatt ccccatccag
     7981 aatgccagcg cgccccccat cgatacctgt tgacgccgca ttcccgccgc gaccggagcc
     8041 gcacagcagg tacacatcat gcccggcagc gaaaacagcg ttcccagcag cgtgccgcga
     8101 aagcgcgatt gcccaagcgt acgcaataac cagtcacgcg ggatcagcac ctgaatcaac
     8161 gacccgagca gtacgcccag caccgccgct ttccataccg cgaggaaata gatcatcgcg
     8221 taatccaacg ccgcctgcca cggattagca tccgcctgcg caaggataga tttaccgata
     8281 ctgtgggttt cggcagcagt aaacgctttg ccgtagtaag gttgccattt cacataccag
     8341 agaccagcaa tgacaacgag aaagaaaagc gcgggtttcc accactgaat gggcgttgcc
     8401 gcctgagatg aagactgacc agtcatagca ttccccagga ataagatatg ataattgagc
     8461 gcgtgaatat tacgctcact atcatttctt gggaataatt attcagctct tttgcgtaat
     8521 tctgaagagc ttaaaatcgt cacaccttca tgctcaggcc gcatcgcctc tgccagcatg
     8581 acccgcgcca cgtctcgcgc atcaatggat ttccagttac ccggtaacaa acggaacagc
     8641 ggcgcaaaaa gcgtttcgtt catccgctgt ttgctacgat cgcccagcaa catcgaaggg
     8701 cgagcaatgg tcaatttcgg ccagttctgg gcgattaatg cttcttccat ctcccctttg
     8761 acgcggttat agaaaaacgg cgagtgggca ttagcaccca tagcactgac taccagcata
     8821 tgctgcgcac caagccgccg cccggttaag gcggtgtcca ctaccagcgt gtaatcggca
     8881 tgaataaacg cctctttact ccccgcttct cgccgcgtgg tgccgagaca acaaaacaca
     8941 atgtcgatgg gatcggtgac ctgcgccagc gcgtcggtca gttgcggatc atggggatta
     9001 aacacccctg acatatcgcc caacggacgt cgcgtcggcg cggctatggc gttaactttc
     9061 ggttcgttaa tcaacatccg cagcaggtga ccgcccacca gccccgttgc gcctgtaatc
     9121 agtacctgac tcatcttcgc tcctttacag aattgtctgc cttgcgctcc ccggctcatg
     9181 caccaggctt aatagaccat gaggtaatta tccccgattg tgggaaattc gcctcatcca
     9241 atgcaacatc gcggaggaag catgagtaag aaaattgccg ttttaatcag tgatgaattt
     9301 gaggattcag aatttacttc acccgcagac gagttccgta aagccggaca cgaagtgatt
     9361 accattgaaa agcaagcggg taaaacggtg aaaggcaaaa aaggagaagc cagcgtggcc
     9421 atcgataaat ccatcgatga agtgacgccc gcagagttcg atgccctgct gctaccgggc
     9481 ggccattcac cggattatct gcgtggcgac aaccgttttg tcaccttcac ccgcgatttt
     9541 gtgaatagcg gcaaacctgt tttcgccatc tgtcacggtc cgcagctgct gatcagcgcc
     9601 gatgtgattc gggggcgcaa actgactgcc gttaaaccga tcattattga tgttaaaaac
     9661 gcgggcgcgg aattttacga tcaggaagtg gtggtcgata aagatcagct ggttaccagc
     9721 cgtacaccgg acgatctgcc agcgtttaac cgcgaggcat tacgcctgct cggtgcctga
     9781 gttacgtagc cagatcattt ttttaccaaa gcccagcgtg ttgtcggtga atttgatttc
     9841 atcaaaccgg atttcccaca ccggtgccga cagcattctg gcaaccggaa agcgacgatt
     9901 gtacgcctgg cgcgcaaggt cgctttcctc accttcaagc ctgcggatct cgcctttaaa
     9961 ttgcacgccg cgaattaacg ctaccgtttt cggctgaccg tttaccgttc cggcaactgc
    10021 cgcctgcggc ccactcatct gcgcgtggcg cgttttttct tccgtcaaaa tgtagaaggc
    10081 gactttctgt gtatcaaaaa gataaaaggc attagcgcac cagagttccc cttcctgctg
    10141 tacacaccag gtgacaacat gttgtttttc cagccaacgg ctgatggcgg tgagtgtttc
    10201 cattgctgtt ctcttttata ctgtgggcct gaccttaaca tgcgacgcag acgatgacac
    10261 cctggtttct ttacttgatc cgtaccgccg acaataagct ttataccggg atcaccacag
    10321 atgtcgaacg ccgctatcag cagcaccaaa gcggcaaagg ggcgaaagca ctgcgcggga
    10381 aaggagaact aacgctggcg ttttccgcgc cagtaggcga tcgttcgctg gcactacggg
    10441 cggaatatcg cgttaagcaa ctgaccaaac ggcaaaaaga gcgtctggta gcggaaggca
    10501 cagggtttgc agaactgttg agcagcctgc aaaccccaaa gattaaaagc gattgaagtg
    10561 ctcgtgatac tcaaccagac cagttacacc gttcagcgcg tcatccgcta aacgatgtac
    10621 ctggaaggca ctttcagtgc ccggccagcg gcaacgcaga tcgtgatgtg ccgccagttc
    10681 aaagccgaaa cggctgtaca gcgccggatc gcccagcgtc accactgcgg catagccgaa
    10741 ctcattaagc gaatcgagtc cttcatagac cagttggcgt gccagcccct gtccacggta
    10801 tttttcatct accgccagcg gtgccatgcc gacccattgc aggtcttcgc cctgcacatc
    10861 aaccggacta aatgccacat agccaatgac ctgaccttcg tcatctgtcg ccaccagccc
    10921 cagcgtcaga aagccatctt cacgcagatc gtgaaccagc ttcgcttccg catcactttc
    10981 gaatgaacga cgcagcaggg catcaatacc cggcgcatca atgggaattt ctactcgaat
    11041 tagcatggtt cacctaccga tgtctgtttg gtttcaggcg cggttttcat tcccgcctca
    11101 acaaaatccg ccagttgcag cagcatcatg cgtaaggctt tcggcatttg ctccagttca
    11161 atggcgtcca tcaggttttt cacatacagc cccagctccg tatcgccttc aattaccagc
    11221 cgacgctgga agaagagcgt atccggatct tgtttacgcg ccgcaatcat cagcagatcg
    11281 ctggcgtcgg cactaaaact cacatcagct tgcgcgttct ggctaacgac cagtttgcca
    11341 ttcaccaccg aggtaaacca ttgcaggtca atatcacgca catgaatact taaccagcgg
    11401 ccttcaagaa actccagctc gccatcatcc aacgcctggc ggaattgcca gcttaagacc
    11461 tgctcaagaa cctggcgttt tagcgcaaat ggcgtcagtt ttaccggtac actcaacaga
    11521 gatggcccca aatgcacaat acgggaacgc agtttatcca acacgagttt tactccctgt
    11581 ttcaacaatc atcctatttt gccatatcag aaaaataaca tagcggtata aatcaacaat
    11641 tccatatgaa attgctgcta ccaccaatac aactttaact gccttaaatc aaaaattgtc
    11701 gcagcaaggt taactaaaat cccagttcgt taacattttt gcgctttgat agcgcaacct
    11761 tcaggaaaaa ttatggagct gctctgccct gccggaaatc tcccggcgct taaggcggcc
    11821 atcgaaaacg gcgcagatgc tgtttatatc gggctaaaag atgataccaa tgcccgtcac
    11881 ttcgccggcc ttaactttac cgagaaaaaa ttgcaggaag cggtgagttt tgtccatcaa
    11941 catcgccgca aacttcacat cgcgattaac acttttgcgc atccggacgg ttacgcccgc
    12001 tggcagcgcg ccgtggatat ggcggcgcag ctgggtgccg acgcgctgat cctcgccgac
    12061 ctcgccatgc tggagtacgc cgccgagcgt tacccgcata ttgagcgtca tgtgtcagtg
    12121 caggcttcgg cgaccaatga agaggcgatt aacttttatc atcgccattt tgacgttgcc
    12181 cgcgtggtgc tgccgcgcgt gttgtcgatt catcaggtga aacaactggc acgggtcaca
    12241 cctatcccgc tggaagtgtt tgctttcggc agcctgtgca ttatgtcgga aggccgttgc
    12301 tatctgtcgt cgtatctgac gggtgagtcg cccaacactg tgggtgcgtg ttctccggcc
    12361 cgtttcgtgc gctggcaaca aacgccgcag gggctggaat cccgcctgaa cgaagtgctg
    12421 atcgaccgtt atcaggacgg cgaaaacgca ggttatccga cgctgtgtaa agggcgttat
    12481 ctggtggacg gcgagcgcta tcacgcgctg gaagaaccca ccagtctcaa taccctggaa
    12541 ctgctgccgg agttaatggc agcgaatatt gcttcggtga aaattgaagg ccgccagcgt
    12601 agcccggcgt atgtcagcca ggtggcgaaa gtctggcgtc aggctatcga ccgttgtaag
    12661 gccgatccgc aaaacttcgt accgcaaagc gcgtggatgg agacgctcgg gtcgatgtcc
    12721 gaaggcacgc agaccaccct tggcgcgtat caccgtaaat ggcagtgaga agagcaatga
    12781 aatattcctt agggccagtg ctgtggtact ggccaaaaga gacgctggaa gaattttatc
    12841 agcaggccgc cgccagcagc gccgacgtga tttatcttgg tgaagcggtc tgtagcaaac
    12901 gccgggcaac caaagttggc gactggctgg agatggcaaa atcgctcgcc ggaagtggca
    12961 agcagattgt gctctccacg ctggcactgg tgcaggcatc ctccgaactg ggcgaactga
    13021 aacgctatgt tgagaacggt gagtttctga ttgaagccag cgatctcggc gtggtgaata
    13081 tgtgcgctga acgcaaactg ccgttcgtcg ccgggcacgc gctgaactgc tacaacgcgg
    13141 tgacgctgaa aatattgctc aaacagggca tgatgcgctg gtgtatgccg gtggagcttt
    13201 cccgcgactg gttggtgaat ctgcttaatc agtgcgatga gctgggcatt cgcaaccagt
    13261 ttgaagtgga agtcctgagc tacggtcatc tgccgctggc ctactccgcc cgctgcttta
    13321 ccgcgcgttc ggaagaccgc ccaaaagatg agtgtgaaac ctgctgcatt aagtatccga
    13381 acgggcgcaa cgtgctgtcg caggaaaacc aacaagtgtt tgtactcaat ggcattcaga
    13441 ccatgagcgg ctacgtttac aacctcggta acgagctggc atccatgcag gggctggtcg
    13501 atgtggtccg cctgtcaccg cagggtactg acactttcgc aatgctcgac gccttccgcg
    13561 ctaatgaaaa tggcgctgcg ccactaccgc tgacggcaaa cagcgactgt aacggctact
    13621 ggcggcggct ggcaggactg gagctgcaag cctaagcaaa tagctcactt tgttaacaac
    13681 tttaactact ctttaatgca gtattaaaga ttaatcggta acaaagtgag ctgttatgac
    13741 tgataaaacc attccgtttt cgctactcga tctggcccct attcccgaag gttcttcagc
    13801 gcgagaagcg ttctcccact ctctcgacct cgcccgtctg gctgaaaagc gcggctatca
    13861 tcgctactgg ctggctgaac accacaatat gaccggtatt gccagtgctg caacatcagt
    13921 tttgattggc tatctggcgg cgaataccac tacgctgcat ctggggtctg gcggtgtgat
    13981 gttgcctaat cactcaccat tggtgatcgc cgaacagttc ggcacgctta atacgttcta
    14041 tccggggcga atcgatttgg ggctgggtcg cgcgccgggt agtgaccagc gaaccatgat
    14101 ggctctacgt cgtcatatga gcggcgatat tgataatttt ccccgcgatg tcgcggagct
    14161 ggtggactgg tttgacgccc gcgatcccaa tccgcatgtg cgcccggtac caggctatgg
    14221 cgagaaaatc cccgtgtggt tgttaggctc cagcctttac agcgcgcaac tggcggcgca
    14281 gcttggtctg ccgtttgcgt ttgcctcaca cttcgcgccg gatatgttgt tccaggcgct
    14341 gcatctttat cgcagcaact tcaaaccgtc ggcacggttg gagaaaccgt atgcgatggt
    14401 gtgcatcaat attatcgccg ccgacagcaa ccgcgacgct gaatttctgt ttacctcgat
    14461 gcagcaagcc tttgtgaagc tgcgccgtgg cgaaaccggg caactgccgc cgccgattca
    14521 aaatatggat cagttctggt caccgtccga gcagtatggc gtgcagcagg cgctgagtat
    14581 gtcgctggtg ggtgataaag cgaaagtgcg tcatggtttg cagtcgatcc tgcgcgaaac
    14641 cgacgccgat gagattatgg ttaacgggca gattttcgac caccaggcgc gcctgcattc
    14701 gtttgagctg gtgatggatg tgaaggaaga attattgggg tagtgtgttt taacgtagga
    14761 agccttatcc gagatggtaa cgctgtccta cacaatgcct gataagcgaa gcgcatcagg
    14821 cattgtgtag gcagcagaaa tgtcggataa ggcaccgctg attactgata caccggcagc
    14881 aaattaaagc tcgataagat atggaccagt gcgttgccaa cgccaaatac cagaatcagc
    14941 ataatcatcg gcttgccgcc ccagacgcgg aatttcgggc taccaaagcg tttacgcgat
    15001 gcgcgggcca acagcgccgg aacaattgcc gcccagatgg tagccgctaa gccagcataa
    15061 ccaatggcgt acaggaatcc gttaggaaac agcaggccac ccacaacagg cggggcaaag
    15121 gtcagcaacg ctgttttcaa acggcccata gccgagtcgt cgaaaccaaa cagatctgcc
    15181 agatagtcaa acaaacccag cgttacgcca aggaacgaac tcgctaccgc aaagtttgag
    15241 aatacgacca gcagaagatc caggctacgg ctgttcagca cgccgcttaa cgcctgtacc
    15301 agcacatcaa tattaccgcc cttctcggcg atgccgataa actccggacg agggatgttg
    15361 cccatcgtcg ccagcaacca gatggtatac agcgccagcg ccatcagcgt accgtacacc
    15421 aggcatttca cgatggtttt cggatctttg ccgtaatact tcatcaggct cggcacgtta
    15481 ccgtgataac caaacgatgc cagacagaat ggcagtgtca tcagcagata cggcgcataa
    15541 gacgcattgc tttcggcgac gttgaacaat gtcgcaggct gtacatgccc cagtaggcta
    15601 ccgaaggtga ggaagaaggt aatgactttc gcacccagca caatcgccgt catccggctg
    15661 accgctttgg tgctcaacca caccacaaac gccaccagca gtgcaaaacc aaaacccgct
    15721 gcccgtgccg ggacgttcaa tgacatctct gcgaaggtat gatgcagaat cgaaccgctg
    15781 gcagaaatat aggcataggt caggatatag agcacaaagg caatggaaat gccgttgacc
    15841 acgttccagc ctttgcccag caaatctttg gtgatggtgt caaagctaga accgattcgg
    15901 taattcaggt tagcttccag aatcatcaag ccggaatgca gcatacagaa ccaggtaaag
    15961 atcagcgccg ccattgacca gaagaaccac gccccggaca tgaccacagg cagagaaaac
    16021 atccctgcgc caataatggt gccgccgata atcaccacgc cgccaagcag cgacggtgac
    16081 gtttgggtgg tggttagtgt tgccatgagg gcttctctcc agtgaaaaat agtgcgactg
    16141 cgttgttatg cattgcactg taccagtaca tgagtacaaa agacagaaaa aaagccccga
    16201 ttgttaaaat cggggctgta tatattattt tacagactgt attcgctgtt cagcgatgat
    16261 tacgcatcgc caccgaaacg acgacgaccg gtagagtcat cacgacgcgg tgcgcggcct
    16321 tcacgacgtt cgccgctaaa acgacgacca tcaccacggc caccttcacg gcgttcaccg
    16381 ctgaagttac gaccgccttc acgacgttcg ccaccgaaac cacgaccacc gccacgacgc
    16441 tcaccgccag tatgcggctg tgcatcgccc agtaactgca tattcatcgg cttgttgaga
    16501 atgcgagtac gcgtaaagtg ttgcagcact tcacccggca tacctttcgg cagttcgatg
    16561 gtggagtgag aagcaaacag cttgatgtta ccgatgtaac ggctgctgat gtcgccttcg
    16621 ttagcaatcg caccaacgat atgacgaact tcaacaccat catcgcggcc cacttcaatg
    16681 cggtacagct gcatatcgcc aacatcacga cgttcacgac gcggacgatc ttcacggtca
    16741 ccacgcgggc cacggtcgtt acgatcgcgc ggaccacggt catcacggtc acggaattca
    16801 cgtttcggac gcatcggcgc atctggcgga acaatcagag tacgttcacc ctgtgccatt
    16861 ttcagcagtg cggcggccag agtttcgaga tccagctctt caccttctgc cgtcggctga
    16921 attttgctca gcagtgcacg gtattgatcc agatcgctgc tttccagctg ctgctgtact
    16981 ttagcggcga atttttccag acgacgtttg cccagcagtt ctgcgttcgg cagttcaact
    17041 tccggaatgg tcagcttcat ggtgcgttca atgttacgca gcagacgacg ctcacggttc
    17101 tcaacgaaca gcagcgcacg gccagcacgg cccgcacgac cagtacgacc gatacggtga
    17161 acgtaagact cagaatccat cgggatatcg tagttaacta ccaggctgat acgctcaacg
    17221 tccaggccac gggccgcaac gtcggtcgca atcaggatgt ccagacgacc atctttcagt
    17281 cgttccagtg tctgctcacg cagcgcctgg ttcatgtcac cgttcagcgc ggcgctgttg
    17341 tagccgttac gctcaagggc ttctgccact tccagagtcg cgtttttggt acgaacgaag
    17401 ataatcgccg catcaaaatc ttccgcttcc aggaaacgta ccagtgcttc gtttttacgc
    17461 ataccccaga cagtccagta gctctggctg atgtcaggac gggtagtcac gctggactga
    17521 atgcgcactt cctgcggctc tttcataaag cggcgggtaa tgcgacgaat cgcttccggc
    17581 atggttgcag agaacagagc ggtctgatga ccttccggga tctgcgccat aatagtttca
    17641 acgtcttcga tgaagcccat gcgcagcatt tcgtcagctt catccagaac cagaccgctc
    17701 agtttagaga ggtccagagt gccacgtttc aggtggtcca gcagacggcc cggagtaccg
    17761 acaacgatct gcggcccctg acgcagggcg cgtaattgca cgtcataacg ctggccgccg
    17821 tacagggcaa ccacatttac gccgcgcatg tgtttagaga aatccgtcat tgcctcagca
    17881 acctgtaccg ccagttcgcg ggtcggtgcc aacaccagaa tctgtggtgc tttcagctca
    17941 ggatcaagat tctgcagcag aggtaaagag aatgctgcag tttttccgct ccccgtctgg
    18001 gccataccca ggacgtcgcg gccattcagc agatgtggaa tacactctgc ctgaattgga
    18061 gatggttttt cgtaacccag atcgttaagg gcttcaagga taggagcctt caggcccaga
    18121 tctgcaaaag tggtttcgaa ttcagccatg tagtacgtgt gcctcaaaat taatggcggc
    18181 cagtctacat aactcatcat gaaattgatc agcaattttc attgaaaagt gtgaaccggc
    18241 tcaaagtagg tgtattaacg aacaacaacg ccctcacccg ttaaggtgat ggcaatcaaa
    18301 aaagattacg ggctgatgtg tacgtcagct attgctggtc cgattctgcc aggtcatctt
    18361 ggtcctggcc caggagcgat aattccaaca atgcgtatcg gtgctcaaca aagttatgaa
    18421 cgttgttggc aaccgccagt ttgaacagtg ccgtggcgct gtccaaatcc cccagactta
    18481 ggtagtactt acctaaatag aagttggttt cactgagatg ctcagcgagc gaggtgttat
    18541 ccgttgcgtc cgccttgagc ctttccatta acgtttgttc gctaatgttg cccaggtaga
    18601 actcgacaat gttccatccc cactgttcct tatccgattt ttcgaagtgc tgtttcaaca
    18661 cttctttagc ctgcttctca tcgagcttct gctcggcgag ataaagccac agactacgga
    18721 aaggatcatt aggatcgtct tgataaaacg ccagcagatc atcttgcgct aacttgtcac
    18781 gaccgccgta atataatgcg atcccgcgat tcaagtgcgc gtagttgtaa gttggatcaa
    18841 gctcaagtac agaatcaaac gcttcatagg cagcatcaaa attgcctgcc tgcgttaaat
    18901 atatgcctaa gtaattgaat acttcaggca tatccggtcg gattgccagc gcttgcgaaa
    18961 aatcgttacg cgctaatgcc ctcagaccga gactatcata caacactccg cgctcatata
    19021 aaagctgtgc gcgttcgtca tcggttaaag cccgactggc aaggatttgt tccatacgtg
    19081 ccagaatcac ttcctgctgt aaagtcggtt gcaatggtac cgcgaggact tcacttttac
    19141 gccaggaagt attactgcat cctgcaagcg taagtgctgt cgcaacgaaa caccagcgca
    19201 aaaaaggctt catttcccac tcccgaagac cacggttgaa tgaacgtcct gttcccggtt
    19261 gctaacaagg cgtcctgccc ggttaaaagc cccccgccgc agcggagggc aaatggcaac
    19321 cttactcgcc ctgttcagca gccggagctt ccggtgctgc agcaggttga gactgctcag
    19381 tcgcttcttt aatgctcaga cggatacggc cctggcgatc aacttccaga actttcaccg
    19441 gtacttcctg acccatctgc aggtaatcgg tcactttctc aacgcgtttg tcagcgatct
    19501 gagagatgtg taccagacct tctttaccgc cgccgatggc aacaaatgcg ccaaagtcaa
    19561 cgatacgggt cactttacca ttgtagacgc ggcccacttc gatttctgca gtgatctctt
    19621 cgatacgacg aatagcatgt ttcgctttct cgccgtcggt cgctgcgatt ttcacagtac
    19681 cgtcatcttc gatttcgatg gtggtgccag tttcttcggt cagagcacgg ataacagaac
    19741 cgcctttacc gataacgtct ttgatcttgt ccgggttgat cttgatggta tggatacgcg
    19801 gagcgaactc agagatatcg ccgcgcggcg cgttgatcgc ctgttccatt acgcccagga
    19861 tatgcagacg cgcaccttta gcctggttca gtgcaacctg catgatctct ttggtgatac
    19921 cttcaatttt gatatccatc tgcaatgcag agataccgtc gcgggaaccc gcaactttga
    19981 agtccatatc gcccaggtga tcttcgtcgc ccaaaatgtc agacagtaca acgtagttgt
    20041 cgccttcttt caccagaccc attgcgatac ccgcaacagc agctttgatc ggcacacctg
    20101 cgtccatcag cgccagagac gcgccgcaca cggaagccat agaagaagaa ccgttggatt
    20161 cggtgatttc agacaccaca cgtacggtgt acgggaattt gtccatatcc ggcatgactg
    20221 ccagcacgcc gcgcttcgcc agacgaccgt gaccaatttc acgacgcttc ggagaaccga
    20281 ccatgccggt ttcgcctacg gagtacggag ggaagttgta gtggaacagg aaggtgtcag
    20341 tacgttcgcc catcagttca tcaagaactt gcgcgtcacg tgcagtaccc agcgttgcgg
    20401 taaccagcgc ctgagtttca ccacgggtga aaagcgcaga accgtgagta cgcggcagca
    20461 cgccagtacg cacatccaga ccacgaatca tatctttttc acgaccgtcg atacgcggtt
    20521 cgcctgccag tacgcggcta cgaacaacgt ttttctcgat agcgtgcaga atttcaccca
    20581 gttcgttttc gtccagggtt tcatcttcag caagcagcgt cgcgatggtt tcagatttga
    20641 tgacatcaac ctgcgcataa cgctcttgtt tgtcggtgat gcggtaagca tcgctcagac
    20701 gagcttcagc cagtgcagca acgcgcgcgt tcagcgcttc gtttaccggc tccggctgcc
    20761 agtcccaacg cggtttaccg gcttctttca ccagttcatt gatgttctga ataacaacct
    20821 gctgttgttc atgaccgaac actactgcgc ccagcatctg gtcttcgctc agcagttcag
    20881 cttcagattc aaccatcagt acagctgctt cagtacccgc aacaaccaga tccagtttgc
    20941 tctctttcag ctcgtcctga gtcgggttca gtacgtactg gtcattgatg taacctacgc
    21001 gggcagcacc aatcggacca ttgaacggaa taccagacag agacagtgct gcggaagcac
    21061 caatcatcgc gacgatatcc gggttaactt gcgggttaac agaaaccacg gtggcgataa
    21121 cctgaacttc gttgacgaag ccttccggga acagcgggcg aatcgggcgg tcaatcagac
    21181 gcgcgatcag ggtttcgcct tcgcttgggc ggccttcacg acggaagaag ctacccggga
    21241 tacgaccagc agcgtaggta cgctcctgat agttaacggt cagtgggaag aagtcctgac
    21301 ctggtttggc ttttttctgg ccaacaacgg taacgaatac cgcggtgtca tccatgctaa
    21361 ccataacagc ggcagtagcc tgacgagcca tcatgccggt ttccagagtc acggtgtgtt
    21421 ggccgtactg gaatttacga acgatcggat taagcaatgt aatatccttt ctctttctta
    21481 gacagtacct tacggcactg gtgttaatac ccgatcttct gcgcatcctc gcgactaatg
    21541 acaaccctaa cccagcccaa tgtgggtaaa gcctctcatt agccgcgcga acctctgcaa
    21601 cggaagatca ttcatagcaa caatacatta gtttccagtg aattgctgcc gtcagcttga
    21661 aaaaaggggc cactcaggcc cccttttctg aaactcgcaa gaattagcga cgcagaccca
    21721 ggcgctcgat gagctgggtg taacgtgcta cgtctttacg tttcaggtag tcgagcagtt
    21781 tacgacgctg agaaaccatg cgcagcagac cacgacggct gtggtgatct tttttgtgct
    21841 ctgcaaagtg gccctgcagg tggttgatct gtgcagtcag cagtgctacc tgaacttcgg
    21901 tagaaccggt gtcgtttgcg tcacgaccaa actcagaaac gattttagct gttgcttcag
    21961 tacttagaga cattttaaaa ctccaaagta tatagaatga aaggacgccg atctctaatt
    22021 cagcgatccc agtgtacgtt acgcaaagtg ttaaacaatt tacgcgacgt taagcggcag
    22081 tattctactc gtagcgacct gttatcgcaa gacggttaac attacgccgg gtattcaacc
    22141 accaggcgac gaggcgcgac gcggccttca tcgtcaattt cgcccatacc gataaacttg
    22201 ccgttctcac cctctgtaac gcgaaccagt ccttccagcg gcgcaccgga tgtacgaacc
    22261 gggttaccat ttttgaagta aacagaagac gttaacggaa gattcaccac cgggtagtcc
    22321 gaagctggac tgtccattgg catcagtaat ggatcaagta actccgcagc cggaatatcc
    22381 tgctgttcgg cttgctcaac cagttcacgc agatgttcca gggtcaccat ccgttcaacc
    22441 ggatatttac ttaccgccag acgacgcaag taaataacat gcgcgccaca accgagtttt
    22501 tcgccgagat cgtcaatgat agtgcggata taagtgcctt ttgagcagtg aatttccagc
    22561 tccagctcat tgccttcatg gcgaataaac agcaattcat aaacggtaat cgggcgcgct
    22621 tcacgtggaa cttcaatgcc ctgacgcgcg tattcgtaca gttttttgcc ctgatatttc
    22681 agtgctgaat acatcgaagg gatctgttcg atatcgccac ggaaggtatc cagcgccgcc
    22741 gccagttgct ctgcactaaa ggttaccgga cgttcttcaa cgatttgtcc gtcggcatca
    22801 gaagtatcgg tacgctgccc aagacgcgca atgacccgat agcgtttgtc ggagtccagc
    22861 agatactggg aaaacttcgt cgcttccccg aggcaaattg gcaacatgcc ggtcgccagc
    22921 gggtccagcg caccggtatg cccggcacgg ttggcgttat aaatccgttt cactttttgc
    22981 agcgcatcgt tgctggacat cccctgcggt ttatccagca acaaaacgcc gttaatgtcg
    23041 cgaccgcgac gacgaggacg actcattagt cctccttgct gtcgtccggg ttaacacgac
    23101 gttcttcgtc atgtttgacc acgctggtca ccaggtttga catgcgcatc ccttcaacca
    23161 gagagttgtc gtagaagaag gtcagttccg gcacgatacg caggcgcatc gctttcccca
    23221 gcaggctgcg gatgaaacca gaagcttcct gcaacgcttt gatgcccgct ttaaccgcgt
    23281 cttcatcttt gtcgttgagg aacgtcacat atactttggc atacgccagg tcgcgagaca
    23341 tttcgacacc ggaaacggtg gtcatcatgc ccagacgagg atctttaatt tcacgctgca
    23401 ggatgagagc gatctctttt tgcatttcct gcgctacgcg ctgcgggcga ccaaattctt
    23461 tcgccataat aaattctcct gacaaaaaag gggctgttag ccccttttta aaattaattt
    23521 caggtggaag ggctgttcac gttggcctga taagacgcgc cagcgtcgca tcaggcaatc
    23581 catgccggat gcggcgtaaa cgccttatcc cgcatggaac cctaaaaacc ttaagcgatg
    23641 gtacgttgga tttcgatgat ttcgaatact tcgatcacat cgccagtgcg gacatcgttg
    23701 tagttcttaa cgccgatacc acattccata ccgttacgga cttcgttaac gtcatctttg
    23761 aagcggcgca gggactccag ctcgccttcg tagataacca cgttgtcgcg cagaacgcgg
    23821 atcgggttgt gacgtttaac cacaccttcg gtaaccatac aacctgcgat ggcaccaaat
    23881 ttcggtgatt tgaatacgtc acgaacttcc gccagaccga taatctgttg tttcagttcc
    23941 ggagacagca taccgctcat tgccgctttc acttcgtcga tcaggttata gatgacggag
    24001 tagtaacgca gatccaggct ttccgcttca attactttac gtgcagaggc atcagcacgt
    24061 acgttgaagc caaccaggat ggcgttggac gccgcagcca gggtagcgtc ggtttcggtg
    24121 ataccaccta cgccagaacc gatgatcttc actttaactt cgtcagtaga cagtttcagc
    24181 aaggagtcgg agatagcttc cacagaaccc tgtacgtctg ccttcaggac gatattcact
    24241 tcgtgaactt cgccttcggt catgttggcg aacatgttct cgagtttaga tttctgctga
    24301 cgcgccagtt taacttcgcg gaatttaccc tgacgataga gtgcaacttc acgcgctttc
    24361 ttctcgtcac gtacaacggt aacttcatca cccgcagccg gaacgccgga caggccgagg
    24421 atttccaccg gaatggacgg acccgcttcc agcacttcct gacccagttc gttacgcatc
    24481 gcacgaacac gaccgtattc gaagccacac agaacgatat cgcccttgtg cagagtacct
    24541 tcacgtacca gaacggtagc aaccggacca cgacctttat cgaggaagga ttcgataacc
    24601 gcaccgctcg ccatgccttt acgtaccgct ttcagttcca gaacttccgc ctgcagcagg
    24661 atagcgtcca gcagctcatc gataccagta cccgctttcg cagacacatg tacgaactgg
    24721 ctttcaccgc cccactcttc cggcaggatg ccgtactggg agagttcgtt cttaacgcga
    24781 tccggatcgg cttctggttt atcgatcttg ttcactgcaa cgaccaccgg aacctgcgcc
    24841 gctttcgcgt gctggattgc ttcgatggtc tgcggcatta cgccgtcgtc ggcagcaaca
    24901 accaggacta cgatgtccgt tgcctgcgca ccacgagcac gcattgaagt aaacgcggcg
    24961 tgccccgggg tgtccaggaa ggtgatcatg ccgttttcag tttcaacgtg gtatgcacca
    25021 atgtgctggg taatgccgcc cgcttcgcca gaggccactt tcgttgaacg aatgtagtcc
    25081 agcagagagg ttttaccgtg gtcaacgtga cccatgatgg tcacaaccgg cgcgcgcggt
    25141 tcagccgctg cacccgtgtc acggtcgctc attaccgctt cttccagctc gttttcacga
    25201 cgcagaataa ctttgtggcc catctcttca gcaaccagct gtgcggtttc ctgatcgata
    25261 acctggttga tggttgccat tgcgcccagt ttcatcatcg ctttgatgac ctgagagcct
    25321 ttaaccgcca tcttgttcgc cagttcgcca acggtgatgg tttcaccgat cacaacgtca
    25381 cggttaacgg cctgagcagg cttctggaag ccttgctgca gcgaagaacc tttacgtttt
    25441 ccgcctttac cgccacgtac tgctgcgcgt gcttcttcac gatcagcttt tgattcagcg
    25501 tgtttgttgc ctttcttcgg acgcgcagct ttcgcgttac gaccacggcc acggccgcct
    25561 tcgacttcac gatcgctttc gtcttctgcc tggcgagcat gttgagaagt agtgacgtga
    25621 taatcgctgg aatcttcagt cggttccgcg ttatcagtcc atttgttttc ttccgccata
    25681 cgacgtgctt cttcagcaac gcgacgtgct tcttcttcga gtttacgacg cgcttcttct
    25741 tcggctttac gcttgagctc tgcagcttcc tgctcacggc gggctttttc agcctgggcg
    25801 tttttagtca tatcgtcttg ttgattgctc actttgtctt tttccgcagc ttcacgtttc
    25861 gcttgttcag cagcttcgcg cttagcttgt tctgcggcct cacgttcagc tttttgttgc
    25921 gcctcacgtt tggccgattc ttctgcctca cgacgggctt gctcttccgc ttcacgctgc
    25981 gcttgctctt ccgcagcaag gcgttcagcc tcttgcggat cgcgtttcac aaaggtgcgt
    26041 ttcttgcgga cttcgatttg taccgatttg ctttttccac cggtaccagg aatgttaagg
    26101 gtgctgcgtg ttttacgttg cagcgtcaat ttgtccgggc ctgaattttt ctgattcagg
    26161 tggtcaatca aagtctgttt ctcttgtgca gacacagagt cgtcagcaga cttccggata
    26221 cctgcatcag caaattgctg taccaggcgt tccacggagg tctgtcgctc tgcggccagc
    26281 gttttaatcg ttacatctgt catgctgttc cttcctgcta cagtttatta cgcttcgtca
    26341 ccgaaccagc aaatattacg ggcagccata atcagtgctc cggctttttc gtcggtcaac
    26401 ccttcgatat cagccagatc atcaatgccc tgttcggcga gatcttccag cgtacaaacg
    26461 ccacgggcgg ccagtttgaa tgccaaatca cgatctatcc cttcaaggtt cagcagatcg
    26521 tcagccggtt tgttatcacc gaggctttct tcctgggcct gtgcaatggt ggccagtgca
    26581 tttttagcac gctcgcgcag tgcttcaacg gtcggctcat caaggccttc gatttccaac
    26641 agctctttca tcggcacata ggccagttct tccagcgtcg agaagccttc ttctaccaga
    26701 acagtcgcga agtcttcgtc gatgtcgaga tatttggtga aggtgtcgat cgctgcgtgc
    26761 gcttccgcct gatgcttagc ctgcaggtcg tcaacggtca ttacgttgag ttcccaaccg
    26821 ctcagctgcg aagccagacg cacgttctga ccgttacggc caatcgcctg cgccaggtta
    26881 ccggcttcaa cggcgatatc catggtgtgt ttatcttcat ccaccacgat agaagcaacg
    26941 tctgccggtg ccattgcgtt aatcacgaac tgcgccgggt tatcatccca caggacgata
    27001 tcgatacgct cgccgcccag ttcagtagaa accgcctgaa cacgcgcgcc acgcatacct
    27061 acgcaagcac ctaccggatc gatacgttta tcgttggttt tcaccgcgat tttcgcacga
    27121 gaacccggat cgcgagccgc tgctttaatt tcaatcactt cttcgccgat ttccggcact
    27181 tcaatgcgga acagttcgat cagcatttcc ggcttggaac gggtgacgaa cagttgcgcg
    27241 ccacgcgctt ccgggcgaac ggaatagagc acgccacgaa cgcggtcgcc agggcggaag
    27301 ttttcacgcg gcagcatatc ttcgcgcagg atcacggctt cagcgttgtt gcccagatcc
    27361 agagagatgt tgtcgcggtt tacttttttc accacgccgg tgatgatttc accttcgtgt
    27421 tcacggaact gatcaaccac catcgcacgt tcggcttcac gcactttctg cacgataacc
    27481 tgttttgccg tctgggtagt gatacggtca aaggtaacag actcaatctg atcttcaacg
    27541 taatcgccca ggttcaggct ttcatcttca taacgtgcgg cttcaagggt gatttccttg
    27601 gtcggctggg tgacttcatc aacaactaac cagcgacgga aggtgtcaaa atcaccgctt
    27661 ttgcgatcga tctgtacgcg gacgtcgatc tcttgttcat attttttctt tgttgctgtc
    27721 gccagcgcgc tttccaatgc ttcgaaaatc ttctcgcgag gtagcgcctt ttcattggat
    27781 acggcttcaa ctacagccaa aatttctttg ttcatcgcgg gcttttcacc tcatccagac
    27841 tattaaaagt ggggaaccag gttcgccttc tggatattac tcagcgcgaa cacttcatct
    27901 ttaccttcga cggtaactgt gatcatttca ccgtctaccg ctttgataac gccctgccat
    27961 ttacgacggt tttgtaccgc catgcggaga accagagtca cctcttctcc gacgaaacgg
    28021 gcgtagtgtt cagccgtgaa cagtgggcga tcgagacccg gtgaggagac ttccaggtta
    28081 taagcaacgg tgatgggatc ttcaacatcc agcacagcac ttacctggtg gctcacatca
    28141 gcacaatcat caacattgat gccatcttca ctatcaatat agatgcgcag tgtggatgtg
    28201 cgaccgcgaa taaattcgat gccaaccagt tcaaaaccca gggcctcaac tggcgcagta
    28261 atcatctctg ttaatttttg ctctaatgtg gacaagccca cccccaagac ataaaaaaag
    28321 ggcctaaagc ccagttattc tgtagtcaga taacaaaaaa ccccgataaa tcggggcttt
    28381 atataactga accctataac cgcaactgcg gtctggagca ctttccagaa ggattttttc
    28441 aaatcccact acgaaggccg aagtcttcac agtatatttg aaaaaggact ctaagggaaa
    28501 gtggttgcgg gggccggatt tgaaccgacg accttcgggt tatgagcccg acgagctacc
    28561 aggctgctcc accccgcgcc tgaaacgtgg caaattctac tcgttttggg taaaaaatgc
    28621 aaatactgct gggatttggt gtaccgagac gggacgtaaa atctgcaggc attatagtga
    28681 tccatgccac attttgtcaa cgtttattgc taatcacgtg aatgaatatc cagttcactt
    28741 tcatttgttg aatacttttg ccttctcctg ctctccctta agcgcattat tttacaaaaa
    28801 acacactaaa ctcttcctgt ctccgataaa agatgattaa atgaaaactc atttattttg
    28861 cataaaaatt cagtgagagc ggaaatctag gctcatcatc agttaattaa gcagggtgtt
    28921 attttatgac gacgattctc aagcatctcc cggtaggtca acgtattggt atcgcttttt
    28981 ccggcggtct ggacaccagt gccgcactgc tgtggatgcg acaaaaggga gcggttcctt
    29041 atgcatatac tgcaaatctg ggccagccag acgaagagga ttatgatgcg atccctcgtc
    29101 gtgccatgga atacggcgcg gagaacgcac gtctgatcga ctgccgcaaa caactggtgg
    29161 ccgaaggtat tgccgctatt cagtgtggcg catttcataa caccactggc ggcctgacct
    29221 atttcaacac gacgccgctg ggccgcgccg tgactggcac catgctggtt gctgccatga
    29281 aagaagatgg cgtgaatatc tggggtgacg gcagcaccta taaaggaaac gatatcgaac
    29341 gtttctatcg ttacggtctg ctgaccaatg ctgaactgca gatttacaaa ccgtggcttg
    29401 atactgactt tattgatgaa ctgggcggtc gtcatgaaat gtctgaattt atgattgcct
    29461 gcggtttcga ctacaaaatg tctgtcgaaa aagcctactc cacggactcc aacatgcttg
    29521 gtgcaacgca tgaagcgaag gatctggaat acctcaactc cagcgtcaaa atcgtcaacc
    29581 ccattatggg cgtgaagttc tgggatgaga gcgtgaagat cccggcagaa gaagtcacag
    29641 tacgctttga gcaaggtcat ccggtggcgc tgaacggtaa aacctttagc gacgacgtag
    29701 aaatgttgct ggaagctaac cgcatcggcg gtcgtcacgg cctgggcatg agcgaccaga
    29761 ttgaaaaccg tatcatcgaa gcgaaaagcc gtggtattta cgaagctcca ggaatggcgc
    29821 tgctgcacat tgcgtatgaa cgtctgttga ccggtattca caacgaagac accattgagc
    29881 agtatcacgc gcatggtcgt cagttgggcc gtctgctgta ccaggggcgt tggtttgact
    29941 cccaggcgct gatgctgcgt gactctctgc aacgctgggt tgccagccag atcactggtg
    30001 aagttaccct ggagctgcgc cgtgggaacg attattcaat cctgaatacc gtctcagaga
    30061 acctgaccta caagccagag cgtctgacga tggaaaaagg cgactcggtg ttctcgccag
    30121 atgatcgtat cggtcaactg accatgcgca acctggatat caccgatacc cgcgagaaac
    30181 ttttcggtta tgccaaaact ggcctcctct cctcctctgc cgcttcgggc gtgccacagg
    30241 tggagaatct ggaaaataaa ggccagtaat tcgacatcaa ccctgccctt caggggtggg
    30301 gttaccttgc ttatcctcag taaactcctt tcttagcatc acaaaatcga aaacatcatg
    30361 gtttgcatct acaacccgtg agtctccttt atagtgtgca atcacttcct caagcgtttg
    30421 cggctgttcc ggctttgtta cccccatcca cgcattaata aggtaattat tgtacgcagt
    30481 ggaaaagata tcgttttccg ttgtgcgatc cacgccatcc ccaagaacgg ggctatacca
    30541 gataaacatc gggacatgat atgcctgctg gctggcctcc ctgcctccat gaaaatagac
    30601 gttcttcttc gtagggtcgc gttccaggcc gtggtcggca aaatacatga ccgaggcgcg
    30661 gcgatctttt aataattcaa aaacctgacc tagcaaacta tctgtgtaat gaatggagtt
    30721 gtcatagcag gcatcctgat cgtcctgcgg ttgaaacacg gcgctggatt gcggataggc
    30781 gctacaagcc ggttcatggc ttccatttaa atgaagaaca atcagtttct tttgctgcgt
    30841 cttttgctgt aacgcttgcg ataaatgcgg caacaacaat tcatcaaatc ctctgacata
    30901 gactgtttcc atggcgcgca tggcgatact ggtaactgct gtaccattct gccgaaaagc
    30961 ggattgcgag cttagccaga aagtctgaaa tcctgcttga ttagccatat taataatgtt
    31021 gtccgggtaa ttatgaatgt catgactcaa aacagaatca gcagttaaag aaaggggaac
    31081 cgacagcgca gtgtaaggtg caccgcttat tgcttgatta aacagtttga tctgttttct
    31141 ttgtgcttcg acttgcggtg tcgtagagcg tgtgtatcca tacaaagaca tattgtcgac
    31201 acgtacagac tcccccacaa tcaacacgta ggtatcaata cctgtatccc tgactgataa
    31261 ttgaaaatac ggcaccgtgt ttgcaattga gagtaatctt tgatgctctt tcgctgctaa
    31321 agcaaaataa ttgagattga aaaacggtgt ataggtagca aatcgcgacg ctagtatata
    31381 tggactgaac gcttttttat tttttgcatc tttataagca aattgacaag cggaaaataa
    31441 actgcccgaa atgacaatca gcaataatat tcctgtcact ttttttgtcg gcaaggaaac
    31501 atcatatttt attattactg ccaaaaaaag aagggataaa aaagaaaaag cacatagata
    31561 agggatatac atccccagca ttttcacaac ttcatccgga tcactctgca gcacactaat
    31621 cgcaaatcca tcattgaaag ttgtaccaaa ggtacaccat gaatagaggc taatactcat
    31681 gtctgccgca gtcagtaaca caaatggtgc ggcaacaagc aggcgaagcg gaagggatga
    31741 tatacgttta acaaccagga tggtcagaac gaaaaacagc aatcgctgaa ccatatgcgc
    31801 tccggaagag gcgactaagt tcgtaatacc aaaaacaata acacaaagat acaacaacca
    31861 atgagattta aaacttctaa caaatttgtt gaatactgtc atccagaaat ccaagttcac
    31921 aaccaatata aacaattatc aacaatgttc aattttatat cagacatgtt tttcaactct
    31981 gatccatatc agaccgaaac actgttagtt ttttcttttt aaatgatgcg gccattgttc
    32041 tcagtaatta aataacatta tcaatgcgtc tctaaacatt acgcagaacg tagccatcag
    32101 tagttatact gacaggagca ggatggttta tcgagaagta aacatatccg tattcgtacc
    32161 ggaactggag ttgacacaat aaagtgccaa ttatgtcagc agaagggaaa agtttataac
    32221 taaggcgtac cggcaccatc gtttcaaggt accagctacg agtaaagcaa ctggacgaga
    32281 tacagatacc tgacaaccat tcctcagacc aggaccaaaa cgaaaagaga cgcttttcag
    32341 cgtctctttt ctggaatttg gtaccgagga cgggacttga acccgtaagc cctattgggc
    32401 actaccacct caaggtagcg tgtctaccaa ttccaccacc tcggcacgga tactactttt
    32461 tagttcggga tatcgctggt cggcttagcc ggagcagctg gctgagtttg ttcggttttc
    32521 gccggcgcac tcaggttttc ccattcgcta cctttattgg ttttattgct attgatgtta
    32581 cccagcacca gactgatgat gaagaataac gttgccagca gcgccgtcat gcgggtcatg
    32641 aagttaccag aaccacttga accaaacagc gtagcggaag cgcctgctcc gaaggaggct
    32701 cccatatcag cgcctttacc ttgctgcagc atgatcagac caacaaggcc aattgccaca
    32761 ataaggaaaa ctactaaaag agcttcgtac ataatcaacc tgttccttgc ggagttgccg
    32821 cgtaccaatg cttcaaccaa taaagcggga gtttttaatc tttcccactg aagcgggtgt
    32881 gaatactaac caaagcgaat gaccttcgca agggcaattt tatcgcattg tatcaactgc
    32941 ggaaaaaaac agcaaaaccg atgtattcgc cgagaaaaaa ggcgacaatc gccgcctttt
    33001 tagccagtta tctaacgctt taaacggctt ttactgcatc ggcgatgcgg tgtgcaaatt
    33061 cagtcacctg cgcttcgtct tcgccttcca ccatcacgcg aattaacggt tcggtgccgg
    33121 atttacgcaa cagcacacgt ccacggctac ccagcgccgc ttcaacttct gcagtcacag
    33181 ctttgactga ttcatgctcc agcggatcgc cgctacctgc ggtgtaacgc acgtttacca
    33241 ggatttgcgg gaacattttc atgccgctgc aaaggtcgtg caggctcata tggttacgcg
    33301 ccatcgccgc cagcacctgc aaaccagcaa cgatgccgtc accggtagtg gttttatcca
    33361 gcaggatcac atgaccggag ttctctgcac cgatacgcca gcctttctcc tgcatttttt
    33421 ccagtacgta gcggtcaccc actttcgcgc gcgcaaatgg aatacctaac tgtttcagcg
    33481 ccagttcaag ccccatgttg ctcatcaatg tacccacagc acctccacgc agctggccct
    33541 gacgaagacc ctcacgcgcg atgatataca tgatctgatc gccatcgact ttattgcctt
    33601 catggtcaac cataatcacg cgatcgccgt cgccgtcgaa ggcaataccg agatccgctt
    33661 tttcagccag cacacgagcc tggagcgcgc gaacgtcggt agcccccact tcggcattga
    33721 tgtttacacc gtttggctca caaccgatag cgataacgtt cgcccccagt tcacgcagca
    33781 cgttcggcgc gatgtggtaa gtcgcaccgt ttgcacaatc caccacaatc ttcagttcac
    33841 tgaggctaag ttcgttcggg aacgtggctt tgcaaaactc gatatagcga cccgcagcat
    33901 caacgatacg gctggcttta cccagttctg ccgaatcaac acagctgatc tctttttcca
    33961 tttccgcttc gatggcctct tctactgcat ccggtagttt ggtgccgtcg atagagaaaa
    34021 atttaatgcc attatcgtag aacgggttat gcgatgcaga tatcacaatt ccggcctctg
    34081 cgcggaaggt acgcgtcaga taagccacgg ccggtgttgg catcggacca gtgaagagtg
    34141 cggaaaggcc cgcagccgcc agacccgctt ccagtgctga ctccagcata tagccagaaa
    34201 tacgcgtgtc tttaccaata atgatcttac gggagccgtg gcgcgccagc actttacccg
    34261 cggcccaacc cagcttaagc acaaaatcag gtgtgatcgg cgcatcccct acacgaccac
    34321 gaatcccatc ggtaccgaaa tatttacgat tactcatagc gtttgttttc ctttgcagac
    34381 agagtggctt ccaccacccg catcgcttct acggtttctt tgacgtcatg aacacgaatg
    34441 atgtgcgcgc cttgcattgc ggcaatgacc gcacaggcca gactaccgct caggcgctcg
    34501 gacggcccca cgttcagcag ctgcccaatc atcgattttc gtgacatacc caccaacagc
    34561 ggcaggttga aatggtgaaa ttcagccagg cgcgccagta atgaatagtt atgggagaga
    34621 tttttaccga aaccgaatcc ggggtcgagc aacaatttct cttttgcgat acccgcctgc
    34681 tcgcaacgtg ctatttgctc aataaagtag cgattcactt ctgcaaagac atcgtcatac
    34741 ttcggcgctt cctgcatggt ttttggattt ccctgcatat gcatcagaca aaccggtaaa
    34801 ccggtttctg cagccgcctc cagagcgcca ggttcggaaa gggagcggat atcgttaata
    34861 atgtgagcgc caactttcgc tgactcacgg atgacttctg gtttggatgt atctaccgag
    34921 atccagactt cgaagcgttg agcaattgcc tcaaccacag gaataacacg ttgcaactct
    34981 tcttcaacgc taacttccgc cgctcctggg cgcgtggact cgccaccaac gtcaatgatc
    35041 gtcgcgccag cgttgatcat cagattcgca tgtttcaccg catctatcag cgagttatgc
    35101 gtgccgccat ccgaaaagga atcaggcgtg acgttgagga tccccattac gtgaggatgg
    35161 ctaaggtcca gtgaagtgcc ctgggcaaag agtttcatgg tgttatccct ggtatgaatt
    35221 gataagaaaa aaccccggag cacgccccgg ggttttcggt acaaatacag tcatctgatg
    35281 cgggaactta cttgtcgcct aactgctctg acatggtgtt acccgggttc ggcgtacgcg
    35341 gttcatcaac cggacgtgga gcctttggac taccattgtc gccagaattg ttagaagcgc
    35401 ctggttcttc ccagcccgct ggcggacgta catcgcgacg tgccatcagg tcatcaatct
    35461 gcggtgcgtc gatagtctca tatttcatga gagcatcttt catcgcatgc agaatatcca
    35521 tattgtcggt cagaagctga cgcgcacgat tatagttacg ctcaatcagt gctttcactt
    35581 cctggtcgat gatacgtgca gtttcatcgg acatatgttt cgctttcgct acgctacggc
    35641 cgaggaacac ttcaccttct tcttccgcgt acagcagtgg acccaatttc tcagagaagc
    35701 cccactgagt caccatgtta cgtgccaggt tggtcgcaac tttaatatcg ttggacgcac
    35761 cggtagaaac atgttccggc ccgtagatga tctcttctgc cagacgacca ccgtacagcg
    35821 tagaaatctg gctttccagt ttctgacggc tggcgctgat tgcgtcgccc tcaggcaaga
    35881 agaaagtcac acccagcgca cgaccgcgtg ggataatcgt cactttgtgc accggatcgt
    35941 gttccggcac caggcgaccg ataatcgcgt gacccgcttc gtggtaagcc gtcgattctt
    36001 tctgcgcttc cgtcatcacc atggagcgac gttccgcacc catcatgatt ttgtctttcg
    36061 ctttctcgaa ctcaaccatc gacacaacgc gtttgttgcc acgagcagcg aacagtgccg
    36121 cttcgtttac caggttcgcc aggtcagcac cggagaaacc aggagtacca cgggcaatga
    36181 ttgccgcgtc gatatcgggt gccaaaggta cgcgacgcat gtgaactttc aggatctgct
    36241 cacgaccacg aacatctggc aagccaacca caacctgacg gtcgaaacgg cctggacgca
    36301 gcagggccgg gtcaagaacg tccggacggt tagtcgcggc gataacgatg ataccttcgt
    36361 taccttcgaa gccatccatc tcaaccagca tctggttcaa agtctgttca cgttcatcgt
    36421 gaccaccgcc cagacctgcg ccacgctggc ggcctacggc gtcgatttca tcgataaaga
    36481 tgatgcacgg tgccgctttc ttcgcctgtt cgaacatatc acgaacacgg gatgcaccca
    36541 caccgacgaa catttctacg aagtcagaac cggagatagt aaagaacgga acttttgctt
    36601 cgcctgcaat cgctttcgcc agcagcgttt taccggtacc cggaggaccg accatcagga
    36661 cgcctttcgg gatcttaccg ccgagtttct ggaagcggct cggctcgcgc agatactcaa
    36721 ccagttcagc aacttcttct tttgcttcgt cgcagcccgc aacgtcagca aaggtcgttt
    36781 tgatctgatc ttccgtcagc atgcgcgctt tgctcttacc aaacgacatg gcacctttgc
    36841 caccgccgcc ctgcatttga cgcatgaaga agatccagac accaatcagc aacagcatcg
    36901 ggaaccagga gatgaagata gaagccagca gacttggttc ttcaggcggt tcaccgacaa
    36961 ccttgacgtt cttggtcaac aggttatcca gtaatttcgg atcctgaacc ggaatgtaag
    37021 tggtataacg gttactatct ttcttggtaa cgttgatttc acgtccgttg atacgcgctt
    37081 cacgaacctg gtcgttattg acctcttgta ggaaggtaga gtaatccacc ttacggccat
    37141 tagactcgct gggcccaaag ctctggaata ctgacatcag cacaacggca atgaccagcc
    37201 agagtattag gtttttcgcc atgtcactca agggattaac ctcttattac aactgtgtta
    37261 aaaacagcgt caggatactc tatatccagc atctttcaaa ctttcgtctg aaatctcccg
    37321 gttagggttt acgcccggtc gctacaatat acacttcccg cgaacgtgca cgagaagagt
    37381 ccggcttacg aactttgacc ttcgtaaaca gggagcgaat ttcccttaga tactcatcga
    37441 aaccttcgcc ctggaacacc ttcacaacaa aactgccacc tggagctaat acatcacgac
    37501 acatttctag cgccagttcc accagataca tggcacgggg gatatccacc gccggtgttc
    37561 cgctcatgtt tggtgccata tcggacatga caacctggac tttgctgtcg ccaacgcgct
    37621 ccagcagtgc tttcatcacc agttcatcac gaaaatcgcc ctgaagaaag tccacaccaa
    37681 cgataggatc cataggtaaa agatcgcaag cgatgatgcg gcctttgccg ccaatttggg
    37741 tgaccacata ttgtgaccaa ccacccggag cagcaccaag gtcgacaacc gtcattcccg
    37801 gtttaaagag tttgtcactt tgctgtattt catcaagttt aaaccaggca cgggaacgta
    37861 accccttttt ctgtgcctgt tgaacatatt tatcgctaaa gtgttcctga agccagcggc
    37921 tggagctggc agaacgcttc ttacctgtca tttaactttc ccattgggat aactcatcgt
    37981 aaccaattgc gtaaattttt acgcgcctat ttggtgatat atgggagatg gcggtagaat
    38041 gacccgtttt caatcccaac gtaagcaaaa aatacgatga atctgagtac taaacaaaaa
    38101 cagcacctga aaggtctggc acatccgctc aagccagttg ttctgcttgg cagtaatggt
    38161 ttgaccgaag gggtgctggc cgagattgaa caagcgttag agcaccatga actcatcaag
    38221 gtgaaaatcg ccaccgaaga tcgcgaaact aaaaccttga tcgtggaagc tatcgtgcgc
    38281 gaaaccggcg cctgtaatgt acaggtcatc ggtaaaacgc tggtgcttta tcgcccaact
    38341 aaagaacgta aaatctcgct gccacgctaa gattatccta aagttacaca catttgctgt
    38401 gtaaaacgag gggttttccg caggcaggag agcaaaatgc cacgctctgt tcgttgataa
    38461 aaggccgcat agcggccttt ttcctttctt tacaatacat caacatcttg agtattgggt
    38521 aattcttaca ggtattccac cttaattact tcaaattcta cttcgccgcc cggcgttttg
    38581 atgaccacaa catcatcttc ttctttgccg atcaggccac gagcaatagg cgagtttaca
    38641 gaaatcaggt tttgtttaaa gtcagcttcg tcatcgccaa cgatgcgata agtctgttct
    38701 tcgtcagaat cgagattcag caccgttacg gtagcaccaa aaataacgcg cccattgttg
    38761 ggcattttgg tgacatcaat cacctgcgcg ttcgacagct tggcttcgat gtctttgata
    38821 cggccttcgc aaaagccctg ctgttcacga gctgcgtggt attcggcgtt ttctttcagg
    38881 tcgccatgct cacgcgcttc cgcgatagca gcaatgattt caggacggcg cacagatttc
    38941 agaaaatcca gctcttcgcg taatttttca gcgccgcgta aggtcatcgg aatagcttgc
    39001 atttgttata cctcttgaat attcctgatg gggcaagtct tcacccaccc cggctgttcg
    39061 gcctgcccgg cataactcct caccgggacc agaagcaaaa aaaataccga cccgggtaca
    39121 ggtcccaggt cagctacaat tcacattttg atagtcattt taccctgaag ttcccgaagg
    39181 gtcatcgttt actttatagg gcgttgcgcc gtagtatgac ggctcgattc caggttgtta
    39241 gcgcgagatt atgcgatttt ccagatttat catcggattg accagctgta tagcgttcag
    39301 tgttcaggcc gcaaatgttg atgagtacat tactcaactc cccgctggtg ccaaccttgc
    39361 cctgatggtg caaaaagtcg gcgcgtcggc ccccgctatt gattaccaca gtcagcagat
    39421 ggcgctgccc gccagtacgc agaaagtgat tactgcgctg gcggcgttga ttcaactcgg
    39481 ccccgatttt cgttttacca cgacgcttga aaccaaaggt aatgtggaaa acggtgtact
    39541 taagggtgac ttagtagcgc gatttggtgc cgatccgacg ttaaaacgtc aggatattcg
    39601 caatatggtc gcgactttga aaaaatctgg cgtcaaccaa atcgatggca atgtgttgat
    39661 agatacctcc attttcgcca gccacgataa agcccccggc tggccatgga atgacatgac
    39721 acaatgcttt agcgctccgc ctgccgccgc catagttgac cgcaactgtt tctccgtctc
    39781 gctctatagt gccccaaaac ctggtgatat ggcttttata cgcgtggcat cttattaccc
    39841 cgttacgatg ttcagccagg tacgcaccct cccccgtggt tctgccgaag cgcaatactg
    39901 cgagctggat gtggtgccag gcgacctgaa ccgctttacg ctgaccggat gcctgccaca
    39961 acgttctgag ccgctcccgt tggcttttgc cgtgcaggat ggtgccagct atgctggggc
    40021 aattctgaaa gatgagttaa aacaggcagg tatcacctgg agcggaacac tgctacgcca
    40081 gactcaggtt aacgaacctg gaacggtagt tgccagtaaa cagtcggccc cgctgcacga
    40141 tctgcttaag attatgctga aaaagtcgga caacatgatt gccgatacgg ttttccgcat
    40201 gatcggccat gcgcgcttca atgtgcctgg aacatggcgg gccgggtcgg acgccgtgcg
    40261 tcagatcctg cgccagcaag ccggtgtcga tattggtaac accattattg ccgatggttc
    40321 agggctttcg cggcataacc tgattgcccc cgccaccatg atgcaggtgc tgcaatacat
    40381 tgcccaacac gacaatgaac ttaactttat ctctatgctg ccgctggcgg gctatgacgg
    40441 ctctttgcag taccgtgcag gtctgcatca ggcgggcgtg gatggcaaag tctcagcgaa
    40501 aaccggctcg ttgcaggggg tatataacct ggcgggattc attaccacgg cgagcgggca
    40561 acgaatggcg tttgtgcaat atctttctgg ctatgcagta gaaccggcgg atcagcgtaa
    40621 tcgccgtatt ccgttagtgc gttttga
//
LOCUS       DADXDL010000035        40183 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.035, whole genome shotgun sequence.
ACCESSION   DADXDL010000035 DADXDL010000000
VERSION     DADXDL010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 40183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40183
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.035"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(285..1175)
                     /gene="galF"
                     /locus_tag="IRB70_002165"
     CDS             complement(285..1175)
                     /gene="galF"
                     /locus_tag="IRB70_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GalU regulator GalF"
                     /protein_id="HBC0632076.1"
                     /translation="MANLKAVIPVAGLGMHMLPATKAIPKEMLPIVDKPMIQYIVDEI
                     VAAGIKEIVLVTHSSKNAVENHFDTSYELEALLEQRVKRQLLAKVQAICPPGVTIMNV
                     RQAQPLGLGHSILCARPVVGDNPFVVVLPDIILDGGTADPLRYNLAAMVARFNETGRS
                     QVLAKRMPGDLSEYSVIQTKEPMVAEGQVARIVEFIEKPDEPQTLDSDLMAVGRYVLS
                     ADIWAELERTQPGAWGRIQLTDAIAELAKKQSVDAMLMTGESYDCGKKMGYMQAFVTY
                     GMRNLKEGTKFRESIKKLLA"
     gene            1928..2962
                     /locus_tag="IRB70_002166"
                     /pseudo
     CDS             1928..2962
                     /locus_tag="IRB70_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152817.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
     gene            3035..4618
                     /locus_tag="IRB70_002167"
     CDS             3035..4618
                     /locus_tag="IRB70_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310895.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerC family protein"
                     /protein_id="HBC0632077.1"
                     /translation="MEWIADPSIWAGLVTLVVIELVLGIDNLVFIAILAEKLPPAQRD
                     RARITGLMLAMVMRLLLLASISWLVTLTQPLFSFRSFTFSARDLIMLFGGFFLLFKAT
                     MELNERLEGKDSNNPTQRKGAKFWGVVTQIVVLDAIFSLDSVITAIGMVDHLLVMMAA
                     VVIAISLMLMASKPLTQFVNSHPTIVILCLSFLLMIGFSLVAEGFGFVIPKGYLYAAI
                     GFSVMIEAFNQLAIFNRRRFLSANQTLRQRTTEAVMRLLSGQKEDAELDAETASMLVD
                     HGNQQIFNPQERRMIERVLNLNQRTVSSIMTSRHDIEHIDLNAPEDEIRQLLERNQHT
                     RLVVTDGDDAEDLLGVVHVIDLLQQSLRGEPLNLRVLIRQPLVFPETLPLLPALEQFR
                     NARTHFAFVVDEFGSVEGIVTLSDVTETIAGNLPNEVEEIDARHDIQKNADGSWTANG
                     HMPLEDLVQYVPLPLDEKREYHTIAGLLMEYLQRIPKPGEEVQVGDYLLKTLQVESHR
                     VQKVQIIPLRKDGEMEYEV"
     gene            complement(5070..6923)
                     /gene="asmA"
                     /locus_tag="IRB70_002168"
     CDS             complement(5070..6923)
                     /gene="asmA"
                     /locus_tag="IRB70_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane assembly protein AsmA"
                     /protein_id="HBC0632078.1"
                     /translation="MRRFLTTLMILLVVLVAGLSALVLLVNPNDFRDYMVKQVAARSG
                     YQLQLDGPLRWHVWPQLSILSGRMSLTAQGASQPLVRADNMRLDVALLPLLSHQLSVK
                     QVMLKGAVIQLTPQTEAVRSEDAPVAPRDNTLPDLSDDRGWSFDISSLKVADSVLVFQ
                     HEDDEQVTIRNIRLQMEQDPQHRGSFEFSGRVNRDQRDLTISLNGTVDASDYPHDLTA
                     AIEQVNWQLQGADLPKQGIQGQGSFQAQWQESHKRLSFNQISLTANDSTLSGQAQVTL
                     TEQPEWQLRLQFPQLNLDNLIPLNETANGENGAAQQGLSQSTLPRPVISSRIDEPAYQ
                     GLQGFTTDILLQASNVRWRGMNFTDVATQMTNKSGLLEITQLQGKLNGGQVSLPGTLD
                     ATSINPRINFQPRLENVEIGTILKAFNYPISLTGKMSLAGDFSGADIDADAFRHNWQG
                     QAHVEMTDTRMEGMNFQQMIQQAVERNGGDVKAAENFDNVTRLDRFTTDLTLKDGVVT
                     LNDMQGQSPMLALSGAGTLNLAEQTCDTQFDIRVVGGWNGESKLIDFLKETPVPLRVY
                     GNWQQLNYSLQVDQLLRKHLQDEAKRRLNDWAERNKDSRNGKDVKKLLEKM"
     gene            complement(6945..7526)
                     /gene="dcd"
                     /locus_tag="IRB70_002169"
     CDS             complement(6945..7526)
                     /gene="dcd"
                     /locus_tag="IRB70_002169"
                     /EC_number="3.5.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004942378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dCTP deaminase"
                     /protein_id="HBC0632079.1"
                     /translation="MRLCDRDIEAWLDEGRLSINPRPPVERINGATVDVRLGNKFRTF
                     RGHTAAFIDLSGPKDEVSTALDRVMSDEIVLDESEAFYLHPGELALAVTLESVTLPAD
                     LVGWLDGRSSLARLGLMVHVTAHRIDPGWSGCIVLEFYNSGKLPLALRPGMLIGALSF
                     EPLSGPAARPYNRREDAKYRNQQGAVASRIDKD"
     gene            complement(7618..8259)
                     /gene="udk"
                     /locus_tag="IRB70_002170"
     CDS             complement(7618..8259)
                     /gene="udk"
                     /locus_tag="IRB70_002170"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBC0632080.1"
                     /translation="MTDQSHQCVIIGIAGASASGKSLIASTLYRELREQVGDEHIGVI
                     PEDCYYKDQSHLSMEERVKTNYDHPSAMDHSLLLEHLQALKRGSAIDLPVYSYVEHTR
                     MKETVTVEPKKVIILEGILLLTDARLRDELNFSIFVDTPLDICLMRRIKRDVNERGRS
                     MDSVMAQYQKTVRPMFLQFIEPSKQYADIIVPRGGKNRIAIDILKAKISQFFE"
     gene            8577..11894
                     /locus_tag="IRB70_002171"
     CDS             8577..11894
                     /locus_tag="IRB70_002171"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBC0632081.1"
                     /translation="MSKQSQHVLIALPHPLLHLVSLGLVSFIFTLFSLELSQFGTQLA
                     PLWFPTSIMMVAFYRHAGRMWPGIALSCSLGNIAASILLFSTSSLNMTWTTINIVEAV
                     VGAVLLRKLLPWYNPLQNLADWLRLAFGSAIVPPLLGGVLVVLLTPGDDPLRAFLIWV
                     LSESIGALALVPLGLLFKPHYLLRHRNPRLLFESLLTLAITLTLSWLSMLYLPWPFTF
                     IIVLLMWSAVRLPRMEAFLIFLTTVMMVSLMMAADPSLLATPRTYLMSHMPWLPFLLI
                     LLPANIMTMVMYAFRAERKHISESETRFRNAMEYSAIGMALVGTEGQWLQSNKALCQF
                     LGYSQEELRGLTFQQLTWPEDLNKDLQQVEKLISGEINTYSMEKRYYNRNGDVVWALL
                     AVSLVRHTDGTPLYFIAQIEDINELKRTEQVNQQLMERITLANEAGGIGIWEWELKPN
                     IFSWDKRMFELYEIPPHIKPNWQVWYECVLPEDRQHAEKVIRDSLQSRSPFKLEFRIA
                     VKDGIRHIRALANRVLNKEGEVERLLGINMDMTEVKQLNEALFQEKERLHITLDSIGE
                     AVVCIDMAMKITFMNPVAEKMSGWTQEEALGVPLLTVLHITFGDNGPLMENIYSADTS
                     RSAIEQDVVLHCRSGGSYDVHYSITPLSTLDGSNIGSVLVIQDVTESRKMLRQLSYSA
                     SHDALTHLANRASFEKQLRILLQTVNSTHQRHALVFIDLDRFKAVNDSAGHAAGDALL
                     RELASLMLSMLRSSDVLARLGGDEFGLLLPDCNVESARFIATRIISAVNDYHFIWEGR
                     VHRVGASAGITLIDDNNHQAAEVMSQADIACYASKNGGRGRVTVYEPQQAAAHSERAA
                     MSLDEQWRMIKENQLMMLAHGVASPRIPEARNLWLISLKLWSCESEIIDEQTFRRSFS
                     DPALSHALDRRVFHDFFQQAAKAVASKGLSIALPLSVAGLSSATLVNDLLEQLENSPL
                     PPRLLHLIIPAEAILDHAVSVQKLRLAGCRIVLSQVGRDLQIFNSLKANMADYLLLDG
                     ELCANVQGNLMDEMLITIIQGHAQRLGMKTIAGPVVLPLVMDTLSGIGVDLIYGDVIA
                     DAQPLDLLVNSSYFAIN"
     gene            complement(11933..12790)
                     /gene="alkA"
                     /locus_tag="IRB70_002172"
     CDS             complement(11933..12790)
                     /gene="alkA"
                     /locus_tag="IRB70_002172"
                     /EC_number="3.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase 2"
                     /protein_id="HBC0632082.1"
                     /translation="MYTLNWQPPYDWSWMLGFLAARAVSGVETVAEDYYARSLAVGEY
                     RGVVTAIPDIARHTLHINLSAGLEPVAAECLAKMSRLFDLQCNPQIVNGALGKLGAAR
                     PGLRLPGCIDAFEQGVRAILGQLVSVAMAAKLTAKVVQLYGERLDDFPEYICFPTPQR
                     LAAADPQALKALGMPLKRAEALIHLANAALEGSLPMTIPGDVEQAMKTLQTFPGIGRW
                     TANYFALRGWQAKDVFLPDDYLIKQRFPGMTPAQIRRYAERWKPWRSYALLHIWYTEG
                     WQPDGTDEL"
     gene            12924..14276
                     /gene="yegD"
                     /locus_tag="IRB70_002173"
     CDS             12924..14276
                     /gene="yegD"
                     /locus_tag="IRB70_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416573.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone"
                     /protein_id="HBC0632083.1"
                     /translation="MFIGFDYGTANCSVAVMRDGKPQLLKMENDSTLLPSMLCAPTRE
                     AVSEWLYRHHDVPADDDETQALLRRAIRYNREEDIDVTAKSVQFGLSSLAQYIDDPEE
                     VWFVKSPKSFLGASGLKPQQVALFEDLVCAMMLHIRQQAQAQLPEAITQAVIGRPINF
                     QGLGGDEANAQAQGILERAAKRAGFRDVVFQYEPVAAGLDYEATLQEEKRVLVVDIGG
                     GTTDCSLLLMGPQWRSRLDREASLLGHSGCRIGGNDLDIALAFKNLMPLLGMGGETEK
                     GIALPILPWWNAVAINDVPAQSDFYSSANGRLLNDLVRDAREPEKVALLQKVWRQRLS
                     YRLVRSAEECKIALSSVAETRASLPFISDELATLISQQGLESALSQPLARILEQVQLA
                     LDNAQEKPDVIYLTGGSARSPLIKKALAEQLPGIPIAGGDDFGSVTAGLARWAEVVFR
                     "
     gene            complement(14288..16228)
                     /gene="yegI"
                     /locus_tag="IRB70_002174"
     CDS             complement(14288..16228)
                     /gene="yegI"
                     /locus_tag="IRB70_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310906.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein kinase YegI"
                     /protein_id="HBC0632084.1"
                     /translation="MKPTLYTATGECVTPGRELGKGGEGAVYDIEEFVDSVAKIYHTP
                     PPALKQDKLAFMAATADAQLLNYVAWPQATLHGGRGGKVIGFMMPKVSGKEPIHMIYS
                     PAHRRQRYPHCAWDFLLYVARNIASSFATVHEHGHVVGDVNQNSFMVGRDSKVVLIDS
                     DSFQINANGTLHLCEVGVSHFTPPELQTLSSFVGFERTANHDNFGLALLIFHVLFGGR
                     HPYSGVPLISDAGNALETDITHFRYAYASDNQRRGLKPPPRSIPLSMLPSDVEAMFQQ
                     AFTESGVATGRPTAKAWVAALDSLRQQLKKCPVSAMHVYPAHLTDCPWCALDNQGVIY
                     FIDLGEEVITTGGDFVLAKVWAMVMASVAPPALQLPLPDHFQPTGRPLPLGLLRREYI
                     ILLEIALSALSLLLCGLQAEPRYIILVPVLAAIWIIGSLTSKAYKAEVQQRREAFNRA
                     KMDYDHLVRQIQQVGGLEGFIAKRTMLEKMKDEILGLPEEEKRALAALHDTARERQKQ
                     KFLEGFFIDVASIPGVGPARKAALRSFGIETAADVTRRGVKQVKGFGDHLTQAVIDWK
                     ASCERRFVFRPNEAITPADRQAVMAKMTAKRHRLESTLTVGATELQRFRLHAPARTMP
                     LMEPLRQAAEKLAQAQADLSRC"
     gene            complement(16225..16986)
                     /gene="pphC"
                     /locus_tag="IRB70_002175"
     CDS             complement(16225..16986)
                     /gene="pphC"
                     /locus_tag="IRB70_002175"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase PphC"
                     /protein_id="HBC0632085.1"
                     /translation="MSWRLVYASTVGTSHISADLPCQDACQMQVAWLNDQQPLLSVFV
                     ADGAGSVSQGGEGAMLAVNEAMAYMSQKVQGGELGLNDVLATDIVLTIRQRLFAEAEA
                     KELAVRDFACTFLGLISSANGTLIMQIGDGGVVVDLGHGLQLPLTPMVGEYANMTHFI
                     TDDDAVSRLETYTSTERAHKVAAFTDGIQRLALNMLNNSPHVPFFTPFFNGLASATQE
                     QLDLLPELLKQFLSSPAVNERTDDDKTLALALWLP"
     gene            complement(16983..17642)
                     /locus_tag="IRB70_002176"
     CDS             complement(16983..17642)
                     /locus_tag="IRB70_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBC0632086.1"
                     /translation="MSEQITFATSDFASNPEPRCPCILLLDVSGSMNGRPINELNAGL
                     VTFRDELLADSLALKRVELGIVTFGPVHVEQPFTSAANFFPPILFAQGDTPMGAAITK
                     ALDMVEERKREYRANGISYYRPWIFLITDGAPTDEWQAAANKVFQGEEDKKFAFFSIG
                     VQGADMKTLAQISVCQPLPLQGLQFRELFSWLSSSLRSVSRSTPGTEVVLEAPKGWTS
                     V"
     gene            complement(17863..17922)
                     /gene="ibsA"
                     /locus_tag="IRB70_002177"
     CDS             complement(17863..17922)
                     /gene="ibsA"
                     /locus_tag="IRB70_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsA"
                     /protein_id="HBC0632087.1"
                     /translation="MMKHVIILVILLVISFQAY"
     gene            complement(18195..18251)
                     /locus_tag="IRB70_002178"
     CDS             complement(18195..18251)
                     /locus_tag="IRB70_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HBC0632088.1"
                     /translation="MMKLLIIVVLLVISFPAY"
     gene            complement(18523..18579)
                     /locus_tag="IRB70_002179"
     CDS             complement(18523..18579)
                     /locus_tag="IRB70_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Ibs family toxin"
                     /protein_id="HBC0632089.1"
                     /translation="MMKLVIIVVLLVISYPAY"
     gene            18858..20105
                     /gene="mdtA"
                     /locus_tag="IRB70_002180"
     CDS             18858..20105
                     /gene="mdtA"
                     /locus_tag="IRB70_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter subunit MdtA"
                     /protein_id="HBC0632090.1"
                     /translation="MKGSYKSLWVIVIVVVIAAIAAFWFWQGRNDSRSAAPGATKQAQ
                     QSPAGGRRGMRSGPLAPVQAATAVEQAVPRYLTGLGTITAANTVTVRSRVDGQLIALH
                     FQEGQQVKAGDLLAEIDPSQFKVALAQAQGQLAKDKATLANARRDLARYQQLAKTNLV
                     SRQELDAQQALVSETEGTIKADEASVASAQLQLDWSRITAPVDGRVGLKQVDVGNQIS
                     SGDTTGIVVITQTHPIDLLFTLPESDITTVVQAQKAGKPLVVEAWDRTNSKKLSEGTL
                     LSLDNQIDATTGTIKVKARFNNQDDALFPNQFVNARMLVDTEQNAVVIPTAALQMGNE
                     GHFVWVLNSENKVSKHLVTPGIQDSQKVVIRAGISAGDRVVTDGIDRLTEGAKVEVVE
                     AQSATTPEEKATSREYAKKGARS"
     gene            20105..23227
                     /gene="mdtB"
                     /locus_tag="IRB70_002181"
     CDS             20105..23227
                     /gene="mdtB"
                     /locus_tag="IRB70_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtB"
                     /protein_id="HBC0632091.1"
                     /translation="MQVLPPSSTGGPSRLFIMRPVATTLLMVAILLAGIIGYRALPVS
                     ALPEVDYPTIQVVTLYPGASPDVMTSAVTAPLERQFGQMSGLKQMSSQSSGGASVITL
                     QFQLTLPLDVAEQEVQAAINAATNLLPSDLPNPPVYSKVNPADPPIMTLAVTSTAMPM
                     TQVEDMVETRVAQKISQISGVGLVTLSGGQRPAVRVKLNAQAIAALGLTSETVRTAIT
                     GANVNSAKGSLDGPSRAVTLSANDQMQSAEEYRQLIIAYQNGAPIRLGDVATVEQGAE
                     NSWLGAWANKEQAIVMNVQRQPGANIISTADSIRQMLPQLTESLPKSVKVTVLSDRTT
                     NIRASVDDTQFELMMAIALVVMIIYLFLRNIPATIIPGVAVPLSLIGTFAVMVFLDFS
                     INNLTLMALTIATGFVVDDAIVVIENISRYIEKGEKPLAAALKGAGEIGFTIISLTFS
                     LIAVLIPLLFMGDIVGRLFREFAITLAVAILISAVVSLTLTPMMCARMLSQESLRKQN
                     RFSRASEKMFDRIIAAYGQGLAKVLNHPWLTLSVALSTLLLSVLLWVFIPKGFFPVQD
                     NGIIQGTLQAPQSSSFTNMAQRQRQVADVILQDPAVQSLTSFVGVDGTNPSLNSARLQ
                     INLKPLDERDDRVQKVIARLQTAVDKVPGVDLFLQPTQDLTIDTQVSRTQYQFTLQAT
                     SLDALSTWVPQLMEKLQQLPQLSDVSSDWQDQGLVAYVNVDRDSASRLGISMADVDNA
                     LYNAFGQRLISTIYTQANQYRVVLEHNTENTPGLAALDTIRLTSSDGGVVPLSSIAKI
                     EQRFAPLSINHLDQFPVTTISFNVPDNYSLGDAVQAIMDTEKTLNLPVDITTQFQGST
                     LAFQSALGSTVWLIVAAVVAMYIVLGILYESFIHPITILSTLPTAGVGALLALMIAGS
                     ELDVIAIIGIILLIGIVKKNAIMMIDFALAAEREQGMSPREAIYQACLLRFRPILMTT
                     LAALLGALPLMLSTGVGAELRRPLGIGMVGGLIVSQVLTLFTTPVIYLLFDRLALWTK
                     SRFARHEEEA"
     gene            23228..26305
                     /gene="mdtC"
                     /locus_tag="IRB70_002182"
     CDS             23228..26305
                     /gene="mdtC"
                     /locus_tag="IRB70_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit MdtC"
                     /protein_id="HBC0632092.1"
                     /translation="MKFFALFIYRPVATILLSVAITLCGILGFRMLPVAPLPQVDFPV
                     IMVSASLPGASPETMASSVATPLERSLGRIAGVSEMTSSSSLGSTRIILQFDFDRDIN
                     GAARDVQAAINAAQSLLPSGMPSRPTYRKANPSDAPIMILTLTSDTYSQGELYDFAST
                     QLAPTISQIDGVGDVDVGGSSLPAVRVGLNPQALFNQGVSLDDVRTAISNANVRKPQG
                     ALEDGTHRWQIQTNDELKTAAEYQPLIIHYNNGGAVRLGDVATVTDSVQDVRNAGMTN
                     AKPAILLMIRKLPEANIIQTVDSIRAKLPELQETIPAAIDLQIAQDRSPTIRASLEEV
                     EQTLIISVALVILVVFLFLRSGRATIIPAVAVPVSLIGTFAAMYLCGFSLNNLSLMAL
                     TIATGFVVDDAIVVLENIARHLEAGMKPLQAALQGTREVGFTVLSMSLSLVAVFLPLL
                     LMGGLPGRLLREFAVTLSVAIGISLLVSLTLTPMMCGWMLKASKPREQKRLRGFGRML
                     VALQQGYGKSLKWVLNHTRLVGVVLLGTIALNIWLYISIPKTFFPEQDTGVLMGGIQA
                     DQSISFQAMRGKLQDFMKIIRDDPAVDNVTGFTGGSRVNSGMMFITLKPRDERSETAQ
                     QIIDRLRVKLAKEPGANLFLMAVQDIRVGGRQSNASYQYTLLSDDLAALREWEPKIRK
                     KLATLPELADVNSDQQDNGAEMNLVYDRDTMARLGIDVQAANSLLNNAFGQRQISTIY
                     QPMNQYKVVMEVDPRYTQDISALEKMFVINNEGKAIPLSYFAKWQPANAPLSVNHQGL
                     SAASTISFNLPTGKSLSDASAAIDRAMTQLGVPSTVRGSFAGTAQVFQETMNSQVILI
                     IAAIATVYIVLGILYESYVHPLTILSTLPSAGVGALLALELFNAPFSLIALIGIMLLI
                     GIVKKNAIMMVDFALEAQRHGNLTPQEAIFQACLLRFRPIMMTTLAALFGALPLVLSG
                     GDGSELRQPLGITIVGGLVMSQLLTLYTTPVVYLFFDRLRLRFSRKPKQTVTE"
     gene            26306..27721
                     /locus_tag="IRB70_002183"
     CDS             26306..27721
                     /locus_tag="IRB70_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0632093.1"
                     /translation="MTDLPDSTRWQLWIVAFGFFMQSLDTTIVNTALPSMAQSLGESP
                     LHMHMVIVSYVLTVAVMLPASGWLADKVGVRNIFFTAIVLFTLGSLFCALSGTLNELL
                     LARALQGVGGAMMVPVGRLTVMKIVPREQYMAAMTFVTLPGQVGPLLGPALGGLLVEY
                     ASWHWIFLINIPVGIIGAIATLMLMPNYTMQTRRFDLSGFLLLAVGMAVLTLALDGSK
                     GTGLSPLAIAGLVAVGVVALVLYLLHARNNNRALFSLKLFRTRTFSLGLAGSFAGRIG
                     SGMLPFMTPVFLQIGLGFSPFHAGLMMIPMVLGSMGMKRIVVQVVNRFGYRRVLVSTT
                     LGLSLVTLLFMTTALLGWYYVLPFVLFLQGMVNSTRFSSMNTLTLKDLPDNLASSGNS
                     LLSMIMQLSMSIGVTIAGLLLGLFGSQHVSVDSGTTQTVFMYTWLSMAFIIALPAFIF
                     ARVPNDTHQNVAISRRKRSAQ"
     gene            27718..29121
                     /gene="baeS"
                     /locus_tag="IRB70_002184"
     CDS             27718..29121
                     /gene="baeS"
                     /locus_tag="IRB70_002184"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     BaeS"
                     /protein_id="HBC0632094.1"
                     /translation="MKFWRPGITGKLFLAIFATCIVLLISMHWAVRISFERGFIDYIK
                     HGNEQRLQLLSDALGEQYAQHGNWRFLRNNDRFVFQILRSFEHDNSEDKPGPGMPPHG
                     WRTQFWVVDQNNKVLVGPRAPIPPDGTRRPILVNGAEVGAVIASPVERLTRNTDINFD
                     KQQRQTSWLIVALATLLAALATFLLARGLLAPVKRLVDGTHKLAAGDFTTRVTPTSED
                     ELGKLAQDFNQLASTLEKNQQMRRDFMADISHELRTPLAVLRGELEAIQDGVRKFTPE
                     TVASLQAEVGTLTKLVDDLHQLSMSDEGALAYQKAPVDLIPLLEVAGGAFRERFASRG
                     LKLQFSLPDSITVFGDRDRLMQLFNNLLENSLRYTDSGGSLKISAEQHDKTVRLTFAD
                     SAPGVSDDQLQKLFERFYRTEGSRNRASGGSGLGLAICLNIVEAHNGRIIAAHSPFGG
                     VSITVELPLERDLQREV"
     gene            29118..29840
                     /gene="baeR"
                     /locus_tag="IRB70_002185"
     CDS             29118..29840
                     /gene="baeR"
                     /locus_tag="IRB70_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BaeR"
                     /protein_id="HBC0632095.1"
                     /translation="MTELPIDENTPRILIVEDEPKLGQLLIDYLRAASYAPTLISHGD
                     QVLPYVRQTPPDLILLDLMLPGTDGLTLCREIRRFSDIPIVMVTAKIEEIDRLLGLEI
                     GADDYICKPYSPREVVARVKTILRRCKPQRELQQQDAESPLIIDEGRFQASWRGKMLD
                     LTPAEFRLLKTLSHEPGKVFSREQLLNHLYDDYRVVTDRTIDSHIKNLRRKLESLDAE
                     QSFIRAVYGVGYRWEADACRIV"
     gene            30020..30352
                     /locus_tag="IRB70_002186"
     CDS             30020..30352
                     /locus_tag="IRB70_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310915.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegP family protein"
                     /protein_id="HBC0632096.1"
                     /translation="MAGWFELSKSSDNQFRFVLKAGNGETILTSELYTSKASAEKGIA
                     SVRSNSPQEERYEKKTASNGKFYFNLKAANHQIIGSSQMYATAQSRETGIASVKANGT
                     SQTVKDNT"
     gene            30500..31861
                     /gene="yegQ"
                     /locus_tag="IRB70_002187"
     CDS             30500..31861
                     /gene="yegQ"
                     /locus_tag="IRB70_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-hydroxyuridine modification protein YegQ"
                     /protein_id="HBC0632097.1"
                     /translation="MFKPELLSPAGTLKNMRYAFAYGADAVYAGQPRYSLRVRNNEFN
                     HENLQLGINEAHALGKKFYVVVNIAPHNAKLKTFIRDLKPVVEMGPDALIMSDPGLIM
                     LVREHFPEMPIHLSVQANAVNWATVKFWQQMGLTRVILSRELSLEEIEEIRNQVPDME
                     VEIFVHGALCMAYSGRCLLSGYINKRDPNQGTCTNACRWEYNVQEGKEDDVGNIVHKY
                     EPIPVQNVEPTLGIGAPTDKVFMIEEAQRPGEYMTAFEDEHGTYIMNSKDLRAIAHVE
                     RLTKMGVHSLKIEGRTKSFYYCARTAQVYRKAIDDAAAGKPFDTSLLETLEGLAHRGY
                     TEGFLRRHTHDDYQNYEYGYSVSDRQQFVGEFTGERKGDLAAVAVKNKFSVGDSLELM
                     TPQGNINFTLEQMENAKGKAMPVAPGDGYTVWIPVPQDLELNYALLMRNFSGETTRNP
                     HGK"
     gene            complement(32191..32508)
                     /locus_tag="IRB70_002188"
     CDS             complement(32191..32508)
                     /locus_tag="IRB70_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310918.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632098.1"
                     /translation="MKKIAAISLISVFLMSGCAVHNDETSIGKFGLAYKSNIQRKLDN
                     QYYTEAEASLARGRISGAENIVKNDAAHFCVTQGKKMQIVDLKTEGAGLHGVARLTFK
                     CGE"
     gene            32922..33821
                     /gene="yegS"
                     /locus_tag="IRB70_002189"
     CDS             32922..33821
                     /gene="yegS"
                     /locus_tag="IRB70_002189"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid kinase YegS"
                     /protein_id="HBC0632099.1"
                     /translation="MAEFPASLLILNGKSTDNLPLREAIMLLREEGMTIHVRVTWEKG
                     DAARYVEEARKLGVATVIAGGGDGTINEVSTALIQCEGDDIPALGILPLGTANDFATS
                     VRIPEALDKALKLAIAGDAIAIDMAQVNKQTCFINMATGGFGTRITTETPEKLKAALG
                     GVSYIIHGLMRMDTLQPDRCEIRGENFHWQGDALVIGIGNGRQAGGGQQLCPNALIND
                     GLLQLRIFTGDEILPALVSTLKSDEDNPNIIEGASSWFDIQAPHEITFNLDGEPLSGQ
                     NFHIEILPAALRCRLPPDCPLLR"
     gene            complement(33903..34676)
                     /locus_tag="IRB70_002190"
     CDS             complement(33903..34676)
                     /locus_tag="IRB70_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020238881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBC0632100.1"
                     /translation="MNSFERRNKIIQLVNEQGTVLVQDLAGVFAASEATIRADLRFLE
                     QKGVVTRFHGGAAKIMSGNSETETQEVGFKERFQLASAPKNRIAQAAVKMIHEGMTVI
                     LDSGSTTMLIAEGLMTAKNITVITNSLPAAFALSENKDITLVVCGGTVRHKTRSMHGS
                     IAERSLQDINADLMFVGADGIDAVNGITTFNEGYSISGAMVTAANKVIAVLDSSKFNR
                     RGFNQVLPIEKIDIIITDDAVSEVDKLALQKTRVKLITV"
     gene            complement(34782..35822)
                     /gene="gatD"
                     /locus_tag="IRB70_002191"
     CDS             complement(34782..35822)
                     /gene="gatD"
                     /locus_tag="IRB70_002191"
                     /EC_number="1.1.1.251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBC0632101.1"
                     /translation="MKSVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPR
                     IFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQ
                     CAKYDFIGSRRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCE
                     NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKFFGAMQTFNSLEMSAP
                     QMQGVLRELRFNQLILETAGVPKTVELAVEIAGPHAQLALVGMLHQDLHLTSTTFGKI
                     LRKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIA
                     RNAMPGKVLLIP"
     gene            complement(35870..37225)
                     /locus_tag="IRB70_002192"
     CDS             complement(35870..37225)
                     /locus_tag="IRB70_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBC0632102.1"
                     /translation="MFSEVMRYILDLGPTVMLPIVIIIFSKILGMKAGDCFKAGLHIG
                     IGFVGIGLVIGLMLDSIGPAAKAMAENFDLNLHVVDVGWPGSSPMTWASQIALVAIPI
                     AILVNVAMLLTRMTRVVNVDIWNIWHMTFTGALLHLATGSWMIGMAGVVIHAAFVYKL
                     GDWFARDTRNFFELEGIAIPHGTSAYLGPIAVLVDAIIEKIPGVNRIKFSADDIQRKF
                     GPFGEPVTVGFVMGLIIGILAGYDVKGVLQLAVKTAAVMLLMPRVIKPIMDGLTPIAK
                     QARSRLQAKFGGQEFLIGLDPALLLGHTAVVSASLIFIPLTILIAVCVPGNQVLPFGD
                     LATIGFFVAMAVAVHRGNLFRTLISGVIIMSITLWIATQTIGLHTQLAANAGALKAGG
                     MVASMDQGGSPITWLLIQVFSPQNIPGFIIIGAIYLTGIFMTWRRARGFIKQEKAVLA
                     E"
     gene            complement(37229..37513)
                     /gene="gatB"
                     /locus_tag="IRB70_002193"
     CDS             complement(37229..37513)
                     /gene="gatB"
                     /locus_tag="IRB70_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIB"
                     /protein_id="HBC0632103.1"
                     /translation="MKRKIIVACGGAVATSTMAAEEIKELCQSHNIPVELIQCRVNEI
                     ETYMDGVHLICTTAKVDRSFGDIPLVHGMPFVSGVGIEALQNKILTILQG"
     gene            complement(37544..37996)
                     /gene="gatA"
                     /locus_tag="IRB70_002194"
     CDS             complement(37544..37996)
                     /gene="gatA"
                     /locus_tag="IRB70_002194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIA"
                     /protein_id="HBC0632104.1"
                     /translation="MTNLFVRSGISFVDRSEVLTHIGNEMLAKGVVHDTWPQALIARE
                     AEFPTGIMLEQHAIAIPHCEAIHAKSSAIYLLRPTNKVHFQQADDDKDVAVSLVIALI
                     VENPQQQLKLLRCLFGKLQQPDIVETLITLPETQLKEYFTKYVLDSDE"
     gene            complement(38006..39268)
                     /gene="gatZ"
                     /locus_tag="IRB70_002195"
     CDS             complement(38006..39268)
                     /gene="gatZ"
                     /locus_tag="IRB70_002195"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatZ"
                     /protein_id="HBC0632105.1"
                     /translation="MKTLIARHKAGEHIGICSVCSAHPLVIEAALAFDRNSTRKVLIE
                     ATSNQVNQFGGYTGMTPADFREFVFTIADKVGFARERIILGGDHLGPNCWQQENANAA
                     MEKSVELVKAYVRAGFSKIHLDASISCAGDPIPLAPETVAERAAVLCFAAESVATDCQ
                     REQLSYVIGTEVPVPGGEASAIQSVHITRVEDAANTLRTHQKAFIARGLTEALTRVIA
                     IVVQPGVEFDHSNIIHYQPQEAQALAQWIENTRMVYEAHSTDYQTRTAYWELVRDHFA
                     ILKVGPALTFALREAIFALAQIEQEIIAPENRSGCLAVIEEVMLDEPQYWKKYYRTGF
                     NDSLLDIRYSLSDRIRYYWPHSRIKNSVETMMLNLQGVDIPLGMISQYLPKQFERIQS
                     GELSAIPHQLIMDKIYDVLRAYRYGCAE"
     gene            complement(39297..40151)
                     /gene="gatY"
                     /locus_tag="IRB70_002196"
     CDS             complement(39297..40151)
                     /gene="gatY"
                     /locus_tag="IRB70_002196"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416599.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit GatY"
                     /protein_id="HBC0632106.1"
                     /translation="MYVVSTKQMLNNAQRGGYAVPAFNIHNLETMQVVVETAASMHAP
                     VIIAGTPGTFTHAGTENLLALVSAMAKQYHHPLAIHLDHHTKFDDIAQKVRSGVRSVM
                     IDASHLPFAQNISRVKEVVDFCHGFDVSVEAELGQLGGQEDDVQVNEADALYTNPIQA
                     REFAEATGIDSLAVAIGTAHGMYASAPALDFSRLENIRQWVNLPLVLHGASGLSTKDI
                     QQTIKLGICKINVATELKNAFSQALKNYLTEHPEATDPRDYLQSAKSAMRDVVSKVIA
                     DCGCEGRA"
BASE COUNT         9533 a        10738 c        10262 g         9650 t
ORIGIN      
        1 ctgcttaaaa aaagaacaaa tggtagtgtc cgctattgcc agtacacctc agaccgcttt
       61 ccctgcactt taggaattgt cgcactaagt gactattcat aaagcattat tgccgctact
      121 ctgaccattg caccacagag gccagaggca aactaccaga agtctccgaa gccatacgtt
      181 tctttacaat cgttataaca ttcacgttat gaataatttc tgcataacgt tatgagcggc
      241 gtggcaaaat acccctgccc tgccgctcac tcttacgccg gcgctcaggc cagcaatttt
      301 ttaatgcttt cgcggaattt ggtaccttct ttcaggttac gcatcccgta ggtgacgaag
      361 gcctgcatgt agcccatttt tttaccgcag tcatagcttt cgccggtcat cagcatcgcg
      421 tcaacggact gcttcttcgc cagttcggca atggcgtcgg ttagctggat acggccccag
      481 gcgcccggct gggttcgttc aagttcagcc cagatatctg ccgacaacac gtagcggccc
      541 accgccatca ggtcggagtc cagggtctgt ggttcgtccg gtttttcaat gaactcaacg
      601 atacgcgcca cctgcccttc cgccaccatg ggctctttgg tctggataac ggagtattcg
      661 gagagatcgc ccggcatgcg tttcgccagc acctgactgc ggccagtctc gttaaaacgg
      721 gcgaccatgg cagcgaggtt atagcgcagc gggtccgcag tgccgccatc gagaatgata
      781 tccggcagca ccaccacaaa cgggttgtcc ccgactaccg ggcgggcgca taggatggag
      841 tggcccagac ccagcggctg tgcctggcgc acgttcatga tggttacacc cggcgggcaa
      901 atggcctgga ctttcgccag cagctggcgc ttcacgcgct gctcaagcag ggcttccagc
      961 tcgtaggagg tatcaaagtg gttttccacc gcattcttcg aggagtgcgt caccagaaca
     1021 atctctttga tcccggcggc gacgatttcg tcaacgatgt actgaatcat tggcttatca
     1081 acgatcggca gcatctcctt tggaattgcc tttgtggccg gcagcatatg catgcctagt
     1141 cctgcgaccg gaataaccgc tttcaaattc gccatattca tcttcacctg tttggttgca
     1201 aaacacgcgg ttttgcaaaa ttgtacatgt cacaaattca ttgaaactga taatacacgg
     1261 atactgcccg agcatatgcc cgccaaattc ttaaattcac tgtcacgtaa aagaatacac
     1321 acaactccct tttaccaaca gttaaaactg agaataatct tattctcgtt caggttattc
     1381 agcggctcgt tcctttgctc cgcacgatgt ggctgagatg cccgtctatc gggacctgtt
     1441 ggacgtcgga cccgccgcgc gtatgcccga aaagaatata tagataataa atttcgccag
     1501 gcaatatact tcagtataaa cagccggata tgacgacata ttagcctgaa tccgcggctg
     1561 tgaactgcga tccaccctat tctgcactca cttcataata tgaattatgc cggttttgta
     1621 agcgggcttc gcgcttcgct tctgctctgc gcatcagcgc tcaccgtgac gaaccgcgcg
     1681 agtaagccct tttgccaccc tcgctgaaac gcagcggata aagttctgat atcggaaagc
     1741 ttattccatg gtcgccgcca tggtgttatt ttttcactgt tcttttccgg aacataattc
     1801 ttatcggttc gcttaatccg ctggaaatat atccacccac ggcagagcga tgtccgcgtc
     1861 gttattgcct gtataagttc acagagatat tgcaattgcc tctggataag taaggggaga
     1921 ttgcactatg caaatgcagc acctgatggt tggctatcct aagtactacc aaacagccga
     1981 ttatgcgttg aggctttcag taatggctga tatagcaaca atgagaatga aggctctgca
     2041 cttctgggat aaacacgata tttctgcagc gtctgaagcc tttggcgtat cctgccgcac
     2101 gccttactgg tggcgtcagt tactgaacaa gggaggacct gaggggccaa tcccgcacag
     2161 taaggcacct ctggtgcgac gaaaaaagca ctggcatccc gatgtgctga aagagattcg
     2221 acgcctcagg acagagctgc cgaacctcgg taaagagcag atttttgttc gcctgaagcc
     2281 ctggtgcgta caacgccacc tgacctgccc gagtgtttcc accatcggca gaatgatcgc
     2341 caccgcacac gataaaatgc ggatgatacc agtacgtctg agctcgcggg gtaaggctct
     2401 gtttgtcaaa aagcgaacca ccaaaccccg caggccaaag cactatcgtc cggtaaagac
     2461 cggagagctc attgggatgg acgccattga gctcagaatg ggtgaaatgc gtcgctatat
     2521 cattaccatg atcgacgaac acagcgatta cgcactggcg ctggctgtgc cgtcgctcaa
     2581 cagtgatatc gtcaatcact ttttcagccg tgcagcccgg ctgtttccta tcggtatcag
     2641 ccagatcatc tcagataacg ggaaagagtt cctgggaagc tttgacaaaa cgctgcagga
     2701 agccgccatc aaacacatct ggacctatcc ctacacgcca aaaatgaacg ctatctgtga
     2761 tcgttttaac cggacattaa gagagcaatt tattgagttt aatgaaattt tactctttga
     2821 ggatctggcg ttgtttaacc agaagctggc ggaatatctg gtgctgtata acagcaaaag
     2881 accccacaag gcgctcgcac taatgacgcc cgtggaatat atgttaaaag agaacaaaaa
     2941 ttgcaatatg tggtggaccc atacattgca ttttagacta atcttatcca tgatcgtgat
     3001 aacacatact gcagtcgtac aggttttaat acatatggaa tggattgccg atccgtcaat
     3061 ctgggcaggt cttgtcacgc tggtggttat cgaactggtg ttgggtatcg ataacctagt
     3121 ctttatcgct atcctcgccg agaagctccc tcccgcccag cgcgaccgag cgcggatcac
     3181 tggcctgatg ctggcgatgg tgatgcgtct cctgctgctg gcctctatct cctggctggt
     3241 cacccttact caaccgctgt tcagcttccg ctcgtttacc tttagcgccc gcgacttaat
     3301 catgctgttt ggtggtttct tcctgttgtt caaagccacg atggagctga acgaacggct
     3361 ggaagggaaa gatagcaata accccacgca acgcaaaggt gcgaagttct ggggcgtggt
     3421 gacacaaata gtggtgctgg acgctatctt ctcactcgac tcggtgatta ccgccatcgg
     3481 gatggtcgac catttactgg tcatgatggc cgccgtggtt atcgctatca gcctgatgtt
     3541 gatggccagc aagccgttaa cccagttcgt taacagtcat ccgacgatcg ttattctctg
     3601 cttaagcttc ctgttgatga ttggctttag tctggtggcg gaaggtttcg gcttcgtcat
     3661 tccgaaaggc tacctgtacg ctgccattgg tttctcggtg atgatcgagg cgttcaatca
     3721 gttggctatc tttaaccggc gacgttttct ttccgctaac cagacactgc gccagcggac
     3781 taccgaagcg gtaatgcgcc tgcttagcgg gcaaaaagaa gatgcggaac tggacgccga
     3841 aaccgcgtcc atgctggtgg atcatggtaa ccagcagatc tttaatccgc aggaacggcg
     3901 gatgattgag cgggtactta atcttaacca gcgtaccgtc agcagcatta tgacgtcgcg
     3961 ccacgatatt gagcatatcg atctcaacgc gccggaagac gagatccgcc agttgctgga
     4021 gcgaaatcag catacgcggc ttgtcgttac tgatggcgat gacgcagaag atttgctcgg
     4081 tgttgttcac gttatcgacc tgttacaaca gtcactgcgc ggcgaaccgc tcaacctgcg
     4141 ggtgttgatt cgtcagccgc tggtgttccc ggaaaccttg ccgttgttac ctgccctgga
     4201 gcagttccgt aatgcccgca cacactttgc ttttgtggtg gatgagtttg gctcggtgga
     4261 agggattgtg acattaagtg acgtcactga aaccattgcc ggtaacttac cgaacgaagt
     4321 ggaagagatc gacgcccgcc atgatattca gaagaatgcg gacggttcct ggacggcgaa
     4381 tggtcatatg ccgctggaag atctggtgca atatgtgccg ctgccgctgg atgaaaaacg
     4441 tgaatatcac accattgccg ggctattgat ggaatatttg cagcgtattc caaaacctgg
     4501 cgaagaagtt caggtggggg attatttgct taaaacgttg caggtagaaa gccatcgcgt
     4561 gcagaaggtg cagattattc cgctgcgtaa ggatggcgag atggagtacg aggtgtgatg
     4621 gtatcggcca ttttacccaa tgctgcgtaa cgccttataa cttcagcaat gaagcgttgt
     4681 ctgtggtaca tggacatcac agcgagggtg tgggtccggc tgtaaatcgc cgaatcgttt
     4741 cctgtaggcc ggggcagccc acatggatgt gggctgaggg cgcgttttac agtgatgtta
     4801 cctcgcgccc gtacccgata gccgaaagga ataagatgag ggaaccacgc cagcggcgat
     4861 ttaccgccgg gagcctgggt tgccagggtg gtggcgattg agccaccctg gcacgttcac
     4921 cggcttgagc gttccatagt agcgaggaac atcaagtgaa cggaacagcc ttcgatctta
     4981 catattcgga atataatggt gccgccacga acgcctgatg cgacgcttta cgcgtcttat
     5041 caggcctaca ggacaggtca cctggtaacc tacatcttct ccagcaactt cttcacatct
     5101 ttgccattgc gggaatcttt attccgctcg gcccagtcgt taagacggcg ttttgcttca
     5161 tcctgtagat gtttacgcag taactgatcc acttgcaggc tgtaattaag ttgctgccag
     5221 ttgccataaa cccgcagcgg tactggcgtt tctttgagga aatcaatcag tttgctttct
     5281 ccgttccagc cacccacgac ccgaatatca aactgggtgt cgcaggtttg ctccgccaga
     5341 ttcaacgtac cagccccgga aagcgccagc atgggcgatt gaccttgcat gtcgtttaac
     5401 gtcacgacgc catccttcaa cgtcaaatcg gtggtaaagc ggtcaagacg cgtcacgtta
     5461 tcgaagtttt cagcggcctt cacatcacca ccattacgtt ctaccgcttg ctgaatcatc
     5521 tgctggaagt tcatcccttc catgcgtgtg tcggtcattt cgacatgtgc ctgtccttgc
     5581 cagttgtggc ggaatgcgtc ggcatctatg tcagcaccgg agaaatcacc agccagtgac
     5641 atctttccgg tcaacgaaat cggatagtta aacgccttca gaatggtgcc aatctcaacg
     5701 ttttccagcc gtggctggaa gtttatccgc ggatttattg atgtcgcgtc caacgtgccc
     5761 ggcagtgaaa cctgtccacc gttaagtttg ccctgcagtt gagtaatttc cagcaaaccc
     5821 gacttgttgg tcatttgcgt ggcaacatct gtaaaattca ttccgcgcca gcgcacgtta
     5881 ctggcctgca acaaaatatc agtcgtaaag ccttgcagtc cctgataggc cggttcatca
     5941 atacgcgaag aaatgaccgg gcgcggcaac gttgattggc tcagcccttg ctgcgcggca
     6001 ccgttctcac cattcgctgt ttcattaagg gggatgaggt tgtcaagatt cagttgcgga
     6061 aattgcagtc tcagctgcca ttccggttgc tctgtcagcg tgacctgtgc ttgcccgctc
     6121 agcgtactgt cattggcggt caaactaatt tggttaaatg aaaggcgttt atgtgactcc
     6181 tgccactggg cctggaaact cccctgcccc tgaatacctt gttttggtaa atctgcaccc
     6241 tgcaactgcc agttaacttg ttcaatagcc gccgttaaat catgcggata atcagaagca
     6301 tctaccgtac cgttaaggga tatcgtgaga tcgcgctgat cgcgattaac ccgcccggag
     6361 aactcaaatg aaccacgatg ttggggatct tgttccattt gcaggcgaat attgcggatt
     6421 gtcacctgct cgtcatcttc atgctggaac accagcacgc tgtccgccac cttaagactg
     6481 gatatatcaa acgaccatcc gcgatcgtct gacagatccg gcaaggtatt gtcgcgcggt
     6541 gcaaccggag cgtcttcact gcgcaccgct tccgtctgcg gcgtcagttg gatcactgcc
     6601 ccttttagca tcacctgctt aacgctcagt tgatgactca gcagtggtaa aagcgccacg
     6661 tccagacgca tgttgtctgc gcgaaccagt ggctggctcg cgccctgggc agtgagagac
     6721 attcgcccgg agaggatact aagctgcggc cagacgtgcc aacgcagtgg cccgtcgagc
     6781 tgcaattgat aaccgctacg tgcagcaact tgcttgacca tatagtcgcg gaaatcattc
     6841 ggattcacca gcaacactaa cgcagataac ccggccacca gcacgaccag gagtatcatc
     6901 agcgtcgtca gaaatcgtct catggtatcc tcaatgggcc tgaattagtc tttatcgatt
     6961 cggctggcta ccgcgccctg ctggttgcga tatttcgcat cttcacggcg gttgtaaggt
     7021 cgcgccgccg ggccggaaag cggctcaaag ctcagcgcac caattaacat gcccggacgc
     7081 agcgccagcg gcagcttacc ggagttgtag aactccagca caatgcagcc agaccagccc
     7141 ggatcgatgc ggtgcgcggt gacgtgcacc atcagcccca gacgcgccag tgaggaacgc
     7201 ccgtccagcc agcccaccag atcggctggc agcgtcaccg actccagcgt caccgccagc
     7261 gccagctctc ctgggtgaag atagaacgcc tcgctttcat cgagaacgat ctcatcgctc
     7321 atcacgcggt caagcgcggt gctcacttca tctttgggac cgctcagatc gataaacgct
     7381 gccgtgtgac cacggaaggt acgaaattta ttgcccaggc gtacatccac cgtcgcgcca
     7441 ttaatacgct ccactggcgg acgtgggttg atcgacaaac ggccttcatc aagccaggct
     7501 tcaatatctc ggtcacacag acgcatggca ttttctcctt tcgcgcatca ctcccttaac
     7561 gccaattacg tcaagggcat accaggttat cactgaacgg tacacaattt atcaagctta
     7621 ttcaaagaac tgacttattt tcgctttcaa tatatcgatc gcgatgcggt ttttcccgcc
     7681 gcgcggcacg ataatgtccg catattgttt agaaggctca atgaattgca ggaacatcgg
     7741 gcgcacggtt ttttgatatt gcgccatcac ggaatccatt gaacgcccac gctcgttaac
     7801 gtcacgcttg atgcggcgca tcaggcagat atccagcggg gtatcaacga aaatggagaa
     7861 gttaagttcg tcacgcaaac gcgcatccgt cagcaacaaa atgccttcga gaatgatgac
     7921 cttcttcggc tcaaccgtca ccgtttcttt catacgcgta tgttcaacat agctgtaaac
     7981 cggcaggtca attgccgagc cgcgtttcaa cgcttgtaaa tgctcaagca acaggctgtg
     8041 atccatcgcg ctgggatggt cgtagttggt cttaacgcgt tcttccatcg acagatggct
     8101 ttgatctttg taatagcagt cttcgggaat tacgccgatg tgttcatcac cgacttgctc
     8161 acgtaattca cgataaaggg tactggcaat aagactcttg ccggaagccg atgcgccagc
     8221 gataccgata atgacgcact gatgagactg atcagtcata tatttagcga cctgattaac
     8281 ctggatgtta ggaagggggc gacgaagcgc caaacgcggc aattataggg atttcatccg
     8341 tctgatacca gtcgaatagc gttgccgcgc gctcagagtt aattgttgac aaagaattcc
     8401 cggtggcaaa ttacgttgat cagttttatg taaggtaaaa aatgttatac gccgttgcgc
     8461 aaattatccg cctttacgtc actttatgag caattcgcat ataaaatgta aaacttttgt
     8521 actagcataa acacagaaac gaatactggc gacctggtct tgcggataaa gcggtaatga
     8581 gcaaacaatc acagcatgta ttaattgccc tgccccaccc gctgcttcac ctggtcagtt
     8641 taggtttagt ctcgtttatc tttacccttt tctcgcttga gctttcgcag tttggcaccc
     8701 aactcgcccc actgtggttc ccgacgtcca tcatgatggt ggcgttttat cgccatgccg
     8761 ggcgcatgtg gccgggaatt gcgctgagct gctcgctggg aaatatcgcc gcatccatcc
     8821 tgcttttttc caccagctcg ctgaacatga cctggacgac catcaatatt gttgaagccg
     8881 tggtcggggc agtgctgcta cgtaaattgc tgccgtggta taaccccttg caaaatctgg
     8941 ctgactggct gcgtcttgca ttcggcagcg ccattgttcc gcctctgcta gggggtgttc
     9001 tggttgtcct gctgacgccc ggagacgatc ctctcagggc atttttgata tgggtactgt
     9061 cagaatccat cggcgctctg gcactggtgc cgctgggatt gttatttaaa ccacactatc
     9121 tgctgcgcca tcgcaaccca cggttgcttt ttgagtcgct gctcacgtta gccatcacac
     9181 tgacgttaag ctggctttcg atgctgtatc tgccgtggcc ttttactttc attattgtgc
     9241 tgttgatgtg gagcgccgtg cgcctgccac gaatggaagc ctttttgatc ttccttacca
     9301 cggtgatgat ggtgtcgctg atgatggccg cggatccctc cctgcttgct acgccgcgta
     9361 catacctgat gagccatatg ccgtggctac cgtttttgct gatcctgctg cccgccaaca
     9421 tcatgacgat ggtgatgtat gcctttcgtg cggaacgcaa acacatttcc gaaagcgaaa
     9481 cccgctttcg gaacgcgatg gaatattccg ccatcggcat ggcattagtg ggcaccgagg
     9541 ggcaatggct gcaatccaac aaagcgctct gccagtttct cggttacagt caggaagaac
     9601 tgcgcggact cacctttcag caactgacct ggccggagga tctcaataaa gatctgcaac
     9661 aggttgaaaa gctgatcagc ggtgaaataa acacctattc aatggaaaaa cgctactaca
     9721 accgcaatgg cgatgttgtc tgggcgttgc ttgccgtctc actggtgcgc cacaccgatg
     9781 gtacgccgct ctattttatc gctcagattg aagacattaa cgagctaaaa cgcaccgaac
     9841 aggtgaatca gcaactgatg gagcgcatca cgctggctaa cgaagcgggc gggattggca
     9901 tctgggagtg ggagcttaag ccgaatattt ttagctggga taagcggatg ttcgagctgt
     9961 atgaaattcc tccgcatatc aaaccgaact ggcaggtgtg gtacgagtgc gtgctgccgg
    10021 aagatcgcca gcacgccgaa aaagtgattc gcgattcatt gcaatcgcgc tctcccttta
    10081 aactggaatt tcgcattgcc gtgaaagatg gcatccgcca tatccgcgcc ctcgccaacc
    10141 gggtactgaa taaagaaggc gaagtcgaac gtctgctcgg cattaatatg gatatgaccg
    10201 aggttaaaca gcttaacgag gcattgtttc aggaaaaaga gcgcctgcac attacgcttg
    10261 attccatcgg tgaagccgtg gtctgtattg atatggcgat gaaaattacc tttatgaatc
    10321 cggtggcgga gaagatgagc ggctggacgc aggaagaagc gttaggtgtt ccactcctga
    10381 cggtgttgca tattactttt ggcgacaacg gaccattaat ggagaacatt tacagtgccg
    10441 acacctcacg ttccgcgatt gaacaagatg tggtgttgca ctgccgaagc ggcggcagct
    10501 acgacgtgca ttacagtatt acgccgttaa gtactctgga cggcagcaat attggttcgg
    10561 ttctggtgat tcaggacgtc accgaatcgc gcaaaatgct gcgccagctg agctacagcg
    10621 cctcccatga tgcactgacg catctcgcca atcgcgccag ttttgagaag caactacgca
    10681 tcctgctgca aacggtaaac agtacacatc agcgacatgc actggtgttt atcgatcttg
    10741 atcgctttaa agcggtgaat gacagcgccg ggcatgcggc gggtgacgct ttgctgcgcg
    10801 aactggcgtc gttaatgctg agtatgctgc gttccagcga cgtgctggcg cgactcggtg
    10861 gggatgaatt tggtctgctg ctaccagact gtaatgttga aagcgcgcgt tttatcgcta
    10921 cacgcattat cagtgccgtg aatgactatc actttatatg ggaaggccgt gtgcatcggg
    10981 taggtgccag tgccgggatt accttgattg atgacaacaa tcatcaggcg gcagaagtga
    11041 tgtcgcaggc tgatatcgcc tgttatgcct ccaaaaatgg tggccggggc cgggtgacgg
    11101 tttacgaacc gcagcaagct gccgcacata gcgaacgggc ggcgatgtcg cttgatgaac
    11161 agtggcggat gattaaagag aatcagttga tgatgctcgc ccacggtgtc gcttcgccac
    11221 ggatcccgga agcgcgtaat ttgtggctga tttcacttaa gctctggagt tgcgaaagcg
    11281 agattattga tgaacaaaca tttcgtcgta gcttcagcga tccggcactt agccatgctc
    11341 ttgaccgacg ggtattccac gattttttcc agcaggccgc aaaagcggtt gccagtaaag
    11401 gcttaagcat cgccctccct ctttccgttg ccggtttgag tagcgccacg ctggtgaatg
    11461 atctgcttga gcagctggaa aatagccctc taccaccacg gttattacat ctgattattc
    11521 cggctgaagc gattttagat cacgcagtaa gcgtgcaaaa actgcggctg gcgggatgtc
    11581 ggatagtgct cagccaggtg ggccgcgatc tgcaaatctt caactcgctg aaagcgaata
    11641 tggcagatta cctgctactt gatggtgagt tatgcgccaa cgtgcagggt aatttgatgg
    11701 atgagatgct gattacgatt attcaggggc acgctcagcg actcgggatg aaaaccatcg
    11761 ccgggccagt cgttttaccc ttagtgatgg atacgctttc tggcatcggc gtcgatctga
    11821 tttatggtga tgtgattgcc gatgcccaac cgctggattt gctggtgaat agcagttatt
    11881 tcgcgattaa ctgagggagc gtttgcccat tgcctgatgc gacgtatcag gcctacaatt
    11941 cgtccgttcc gtctggttgc cagccttccg tataccagat atgcaacagc gcataagaac
    12001 gccagggctt ccagcgctcg gcataacggc ggatttgtgc cggtgtcatc cccggaaatc
    12061 gctgtttaat cagataatca tccggcagaa aaacatcttt cgcctgccag ccacgcaaag
    12121 cgaaataatt cgccgtccag cgcccgatac ccggaaaagt ttgcagcgtt ttcatcgcct
    12181 gctccacatc gcccggaatt gtcattggta agctgccctc cagcgccgca tttgccagat
    12241 gaatcagtgc ctctgcccgt ttcaacggca tgcctaacgc ttttaatgcc tgcgggtcgg
    12301 ctgctgccag ccgctgaggc gtggggaagc agatatactc cggaaaatca tccagccgtt
    12361 cgccataaag ctgtacaact ttggcagtca attttgccgc catcgccacg ctcaccagtt
    12421 ggcctaaaat cgcccgcaca ccctgctcaa aagcatcaat acagccgggt aaacgcaatc
    12481 cgggccgcgc cgcgcctaac ttgcccaacg caccgttaac aatctgcggg ttacattgca
    12541 gatcaaacag gcggctcatt ttcgccagac actcagcggc aacgggttct aaacctgcac
    12601 ttaaatttat gtgcagagta tggcgggcta tatccggaat agcagtcacc acgccgcgat
    12661 attcgcccac cgccagacta cgggcataat aatcctcagc gaccgtttcc acaccactca
    12721 ccgcacgggc ggcgagaaat cccaacatcc acgaccagtc atacggcggc tgccagttca
    12781 gggtatacat cgcatctcct tattcatccg ctttcagcat aaacgttatt cagacgctac
    12841 gctttgcttt catattccgg ttgtcgcgac ggcaacattt cgctaaagtc acgccccttc
    12901 ttcaccggca tggggattaa ttcgtgttta ttggttttga ttacggtaca gcaaactgtt
    12961 cagtggcggt catgcgtgac ggtaaaccgc aattactgaa aatggaaaac gacagcacgc
    13021 tgctgccttc aatgctttgc gcgccaacgc gtgaagcagt aagtgaatgg ctgtaccgcc
    13081 atcatgatgt tccggcagac gacgatgaaa cgcaggcgct gttacgtcgg gcgattcgtt
    13141 ataaccgcga agaagatatc gatgttacgg cgaaaagcgt gcagttcggt ctttcctcac
    13201 tggcacagta cattgatgat ccagaagaag tgtggtttgt gaaatcacca aaatcgttcc
    13261 tcggtgccag cggcttaaaa ccgcagcagg tagcgctgtt tgaggatctg gtctgcgcaa
    13321 tgatgttgca cattcgccag caggcgcagg cgcagctgcc agaagcgatt actcaggcgg
    13381 tgattggtcg cccgatcaac ttccaggggc tgggcggcga tgaagcaaac gcccaggcgc
    13441 aagggattct ggaacgcgcg gcgaagcgtg ccggattcag ggacgtggta ttccagtacg
    13501 agccggtcgc ggctgggctg gattacgaag ccaccttgca ggaagaaaaa cgggtgctgg
    13561 tggtggatat cggcggtggt acgactgact gttcattgct gctgatgggg ccgcagtggc
    13621 gttcgcgtct cgatcgtgaa gccagcctgc tgggtcacag tggttgccgt attggcggta
    13681 acgatctgga catcgcactg gcgtttaaaa acctgatgcc gttactgggc atgggtggcg
    13741 aaaccgaaaa aggcatcgcc ctgccgattc tgccgtggtg gaatgcggtt gccatcaacg
    13801 acgtacctgc gcagagtgat ttctacagta gtgccaacgg tcgtctgctt aacgatctgg
    13861 tacgcgatgc ccgcgaaccg gaaaaagtgg ccctgctaca gaaagtctgg cgtcagcgtt
    13921 taagctatcg cctggtgcgt agcgcagaag agtgcaaaat tgctctttca agcgtagcgg
    13981 aaacccgcgc ctcactgccg tttatcagcg atgaactggc tacgctgatt agccagcaag
    14041 ggctggaaag cgccctcagc cagccactgg cgcggattct ggaacaggtg caactggccc
    14101 tggataacgc ccaggaaaaa ccggacgtta tctacctgac cggcggtagc gcccgttcgc
    14161 cgctgattaa aaaagcgctg gcagaacagt tgccgggaat tccgattgca ggcggcgatg
    14221 actttggctc cgtcaccgcc gggctggcac gctgggcgga agtggtgttt cgttaaaaga
    14281 aaatggctca gcagcggctt aaatctgcct gcgcctgagc cagtttttct gccgcctgac
    14341 gtaacggttc catcaacggc atggtccgtg ctggagcatg aaggcggaat cgctgcaact
    14401 ctgtcgcgcc gacagtcaac gtcgattcca gccgatgtcg tttggcggtc attttcgcca
    14461 ttaccgcttg tctgtctgct ggcgttatcg cttcattcgg cctgaacaca aaacggcgtt
    14521 cacagctcgc tttccagtcg ataaccgcct gggtcagatg gtcgccaaac cctttcactt
    14581 gcttaacgcc acgacgggta acatctgcgg ctgtttcaat accaaaagac cgtaacgccg
    14641 ctttacgcgc agggccaacg ccgggaatag aggcaacatc aataaaaaat ccctccagaa
    14701 acttctgctt ctgccgttcc cttgcagtgt catgaagtgc tgccagagcg cgtttctctt
    14761 cttccggtaa cccgagaatt tcgtccttca ttttttcgag catcgtccgt ttggcgataa
    14821 aaccttccag gccgcctacc tgctggatct ggcggactaa atggtcatag tccattttcg
    14881 cacgattaaa tgcctcacgg cgttgctgaa cttctgcttt gtacgctttg cttgtcagac
    14941 tgccaataat ccagatagcc gccagcacag gaaccaaaat aatataacgc ggttctgcct
    15001 gaaggccgca aagcagcagc gataatgctg acagtgcgat ctcaagcaga atgatgtatt
    15061 cgcgccgtaa caggcctaaa ggaagcggcc tgccagtcgg ttggaaatga tcgggtaatg
    15121 gcagttgcaa tgctggcggt gctactgacg ccatcaccat cgcccagact tttgccagca
    15181 caaaatcccc gccggtggta atgacctctt cgccgagatc aataaaatag ataacgcctt
    15241 gattatccag cgcacaccac gggcagtcgg tcaaatgagc gggataaaca tgcattgccg
    15301 aaacgggaca tttctttaac tgttggcgca gagaatcaag tgccgctacc cacgctttag
    15361 ccgtcggacg cccggttgcc acgccacttt ccgtgaatgc ctgctgaaac atggcttcaa
    15421 catcactcgg taacatcgat agcggaatcg atcgtggcgg cggttttaaa ccacgtcgct
    15481 gattatctga cgcgtaggca taacggaaat gggtaatatc cgtctccagc gcattacccg
    15541 catcagagat aagcggcaca ccagaataag gatgccgacc accaaacaag acgtgaaata
    15601 tcagcaaggc aaggccaaaa ttatcgtgat tcgcggtgcg ttcaaagccg acaaatgacg
    15661 acaaggtttg tagctctggc ggcgtaaaat gcgacacacc gacttcgcat aaatgcaacg
    15721 tgccattagc gttaatctga aaggagtcgc tatcaatcaa taccactttg ctgtcgcgac
    15781 ctaccataaa actgttctgg tttacgtcac ccacgacgtg cccgtgctcg tgaaccgtag
    15841 caaaagatga agcaatattg cgcgcaacat agagtagaaa atcccacgca caatgagggt
    15901 aacgttgacg acgatgtgcc gggctataga tcatatgaat cggttcttta ccagaaactt
    15961 ttggcatcat aaaaccgata acttttccgc ctcgtccacc gtgaagcgtt gcctgcggcc
    16021 aggcgacata attcaacaat tgcgcgtcag ctgtcgcagc cataaaggca agtttgtcct
    16081 gttttaaggc gggtggcggc gtgtgataaa tcttggcgac gctatcgaca aactcctcga
    16141 tatcataaac cgcaccttca ccgcctttgc ccagttcacg gcctggcgta acgcactcac
    16201 cagtagcagt atataaagtg ggtttcatgg taaccacagc gccagtgcca acgttttatc
    16261 atcatcggta cgctcgttta ccgccgggct ggacaaaaac tgctttaaca attcaggtaa
    16321 taaatcgagt tgttcctgcg ttgctgacgc cagtccattg aaaaacgggg taaaaaaagg
    16381 cacatgcgga gaattattca acatatttaa cgccagccgc tgaataccat ccgtaaatgc
    16441 tgcaacttta tgcgcacgct cagtactggt gtaagtttcc agtctggaaa cagcatcgtc
    16501 atcggtaatg aagtgcgtca tgttggcata ttcacccacc atcggcgtga gaggcaattg
    16561 cagaccgtga cccaaatcta ccaccacgcc gccatcgcca atctgcataa tcaaggtgcc
    16621 attagctgat gaaatcaatc ccaaaaacgt gcaggcaaaa tcgcgaaccg ctaattcttt
    16681 ggcttccgcc tcggcaaaaa gtcgctgacg aatggtcagc acaatgtccg ttgcgaggac
    16741 atcattaagc cccaattccc cgccctgcac tttttgcgac atataagcca tcgcttcatt
    16801 gacggcgagc atcgcacctt cgccaccctg cgagacgctg cctgcgccat cagcgacaaa
    16861 taccgacaat aatggctgct ggtcatttaa ccaggcaacc tgcatctggc aggcatcctg
    16921 gcaaggcaag tccgcgctga tgtgcgacgt tccaacggtt gatgcataga ccagacgcca
    16981 gctcacactg acgtccagcc ttttggcgct tccagcacaa cttccgttcc cggcgtggag
    17041 cgggaaaccg aacgcagcga actggataac cagctaaaca gttcacggaa ttgtaatccc
    17101 tgcagtggca aaggctgaca aacgctgatt tgtgccaaag tcttcatatc cgccccctga
    17161 acaccgatgg aaaagaaggc aaacttctta tcttcttccc cctgaaacac tttgttggcg
    17221 gcagcctgcc actcatcggt tggagcgcca tcggtgatca ggaaaatcca cgggcgataa
    17281 taggaaatac cattggcgcg atactcacgt ttgcgctcct caaccatatc cagggctttg
    17341 gtaatggcgg cccccattgg tgtatcgccc tgggcaaaca ggatgggcgg gaaaaaatta
    17401 gcggcgctgg taaagggttg ttccacatgc accgggccga acgtcacaat accgagttcc
    17461 actcttttta aggccagcga atcggcaagc agctcatcgc gaaaggtaac caatccggcg
    17521 ttaagttcat taatgggtct accgttcata gaaccagaaa catccagcag caaaatgcag
    17581 gggcaacgtg gttccgggtt actggcaaaa tcgctggtgg caaacgtgat ttgttcgctc
    17641 ataagaaatc ctttcttaga gaattattga ggtccggtat cataccgact gcaacaatga
    17701 aatatgagca ggcaaagcaa ctttcagaat taggcccggc ggcgcagaaa attttgctat
    17761 tcgcctcgca agaacggaga gccgtcgatt gacactaagg gcggagtgac ataatttcag
    17821 gagtgagggt tagggagagg tttccccctc cccctggtgt tcttagtaag cctggaagct
    17881 aatcactaag agtatcacca gtatgatgac gtgcttcatc ataacccttt ccttattaaa
    17941 agccctcttc tccgggagag ggtttcccgt ttcagcgtcc cgctgaaatc gtcggcttac
    18001 ctcctttcgc cctgaatgca gtctatcgct aacgcgtgaa caaaatagtt tcctctgtga
    18061 ttattgcgta acgactcgca aagaatattt gctggcagga tcgcagactg caaagcctgc
    18121 agattgacaa tcttatcgtg aaggcataat ttcaggagtg agggtagagc ggggtttccc
    18181 ccgccctggt agtcttagta agcggggaag cttatgacta agagcaccac gatgatgagt
    18241 agcttcatca tgaccctttc cttatttaag gccccttcct cgggaggggc tttcccgttt
    18301 cagcgtcccg ctgaaatcgt cgacttacct cctttcgccc tgtatgcagt ctatcgctga
    18361 cttgcggata aaatagtttc cagtgtgatt attgcgtaac gtctcgcaaa gaatatttgc
    18421 tggcaggatc gcagactgca aagcctgcag attgacaatc ttatcgtgaa ggcatacttt
    18481 caggagtgag ggtagagcgg ggtttccccc gccttggtag tcttagtatg ctgggtagct
    18541 aatcactaag agcaccacga tgatgactaa cttcatcatg accctttcct tatttatggc
    18601 cccttcctcg ggaggggctt tcccgtttca gcgtcccgct gaaatcgtcg gcttacctcc
    18661 tttcgccatg caagcagtct atcgctaacg cgtagataaa atagtttcct gtgttattac
    18721 tggatgcgtg ctcgcaaatg tgcccgccat tcagacgatt cccgatagtg tttcataatt
    18781 cctccatttt tctcccttat tggctggcta cactagtatc attccgcgaa acgtttcagg
    18841 aagagaaact cttaacgatg aaaggtagtt ataaatccct ttgggtaatc gtaatcgtgg
    18901 tggttatcgc cgccatcgcc gcattctggt tttggcaagg ccgcaatgac tcccggagtg
    18961 cagccccagg ggcgacgaaa caagcgcagc aatcgccagc gggtggtcgc cgtggtatgc
    19021 gttccggccc attagccccg gttcaggcgg cgaccgccgt agaacaggca gttccgcgtt
    19081 acctcaccgg gcttggcacc attaccgccg ctaataccgt tacggtgcgc agccgcgtgg
    19141 acggccaact gatagcgtta catttccagg aaggccagca ggtcaaagca ggcgatttac
    19201 tggcagaaat tgacccaagc cagttcaaag ttgcattagc acaagcccag ggccaactgg
    19261 caaaagataa agccacgctt gccaacgccc gccgtgacct ggcgcgttat cagcaactgg
    19321 caaaaaccaa tctcgtatct cgtcaggaac tggatgccca acaagcgctg gtcagtgaaa
    19381 ccgaaggcac cattaaggct gatgaagcaa gcgtcgccag cgcgcagctg cagctcgact
    19441 ggagccgtat taccgcacca gtcgatggtc gcgttggtct caagcaggtt gatgttggta
    19501 accaaatctc cagtggtgat accaccggga ttgtggtgat cacccagacg catcctatcg
    19561 atttgctctt taccctgccg gaaagcgata tcactaccgt agtacaggcg caaaaagccg
    19621 gaaaaccgct ggttgttgaa gcctgggatc gcaccaactc gaagaaatta agtgaaggca
    19681 cgctgttaag tctcgataac caaatcgatg ccactaccgg tacgattaaa gtgaaagcac
    19741 gctttaataa tcaggatgat gcactgtttc ccaatcagtt tgttaacgcg cgtatgttag
    19801 tcgacaccga acaaaacgcc gtggtgatcc ccaccgccgc cctgcaaatg ggcaatgaag
    19861 gccattttgt ctgggtgctg aatagcgaaa acaaggtcag caaacatctg gtgacgccgg
    19921 gcattcagga cagtcagaaa gtggtgatcc gcgcaggtat ttctgcgggc gaccgcgtag
    19981 tgacagacgg cattgatcgc ctgaccgaag gggcgaaagt ggaagtagtg gaagcccaga
    20041 gcgccaccac tccggaagag aaagccacca gccgcgaata cgcgaaaaaa ggagcacgct
    20101 cctgatgcag gtgttacccc cgagcagcac aggcggccca tcgcgcctgt ttattatgcg
    20161 tcctgtcgcc accacgctgc tgatggtggc gatcttactc gccgggatta tcggttatcg
    20221 tgccctgccc gtttcggcgc tgccggaagt ggactatcca accattcagg tggtcaccct
    20281 ctacccaggt gccagcccgg atgtcatgac ctctgccgtt accgcgccgc tcgaacgcca
    20341 gttcgggcag atgtccggcc tgaaacagat gtcgtcgcaa agttccggcg gtgcgtcagt
    20401 tatcactttg cagttccagc taacattacc gctggatgtc gccgagcagg aagtgcaggc
    20461 cgcgattaac gctgcgacca acctgctacc gagcgatctg cctaacccgc cggtttacag
    20521 caaagtgaac ccggcagatc cgccaatcat gacgctcgct gtcacctcaa ccgccatgcc
    20581 gatgacgcaa gtggaagata tggtggaaac ccgcgtcgcg caaaaaatct cgcagatttc
    20641 cggcgtcggc ctggtgacgc tttccggcgg ccagcgtccg gctgttcgcg tcaaacttaa
    20701 cgcccaggcg attgccgccc tcggcctgac cagcgaaacc gtgcgcaccg ctattaccgg
    20761 cgctaacgtt aactcggcaa aaggtagcct cgacggccct tcccgtgcgg tcacactttc
    20821 cgcgaacgac cagatgcaat ccgccgaaga gtatcgccag ctgatcatcg cctaccagaa
    20881 cggcgcgccg attcgtctgg gcgatgtcgc aaccgtagag caaggagcag aaaacagctg
    20941 gctcggcgcg tgggcgaaca aagaacaggc cattgtgatg aatgttcagc gccagcccgg
    21001 tgctaacatt atctccaccg ccgacagcat ccggcagatg ctgccacaac tcaccgagag
    21061 tttgccgaaa tcggtaaaag tgacggtgct ttctgaccgc accaccaaca tccgcgcatc
    21121 ggtcgacgat acccagtttg aactgatgat ggctatcgcg ctggtagtca tgattatcta
    21181 cctgtttttg cgcaatattc cggcgaccat tattcctggc gtcgcagtgc cgctgtcgtt
    21241 aatcggcacc ttcgcagtca tggtgtttct cgatttttcg atcaataacc tgacgctgat
    21301 ggcgttaact atcgccaccg gattcgtggt cgatgacgcc atcgtggtga tcgagaacat
    21361 ttcgcgctat atcgaaaaag gcgaaaaacc gctggcggcg gcgctcaaag gcgcaggtga
    21421 aatcggtttt accattatct cgctgacctt ctcgctgatt gcagtgttga tcccactgct
    21481 atttatgggc gatatcgtcg ggcgactgtt ccgcgaattt gcaattactc tggcagtcgc
    21541 gattttgatc tcagccgtgg tgtcgctgac tctgacgccg atgatgtgcg cgcggatgct
    21601 cagccaggag tcgctgcgta aacagaatcg cttctcccga gcctcggaga aaatgttcga
    21661 caggataatc gccgcctatg gtcagggact tgcgaaagtg ctgaatcatc cgtggctgac
    21721 cttaagcgtg gcgctcagca cgctgctgct tagcgtgctg ttgtgggtgt tcattccgaa
    21781 aggtttcttc ccggtacagg acaacggcat tattcagggc actttgcagg caccgcaatc
    21841 cagctccttt accaatatgg cccagcggca acgccaggtc gcggatgtga ttttgcagga
    21901 tccggcagtg caaagtctga cctcatttgt tggcgttgat ggcactaacc cgtcgctgaa
    21961 cagtgcgcgt ttgcagatca acctcaaacc gttggatgaa cgtgatgatc gggtgcaaaa
    22021 agtcatcgcc cgtctgcaaa cggcggtgga taaagtgccg ggcgtcgatc tcttcctgca
    22081 accaacgcag gacctgacca tcgatactca ggtcagccgc acccagtacc agtttacctt
    22141 gcaggccacg tcactggatg cgctcagtac ctgggtgcca cagttgatgg aaaaactcca
    22201 gcaactgcca cagctttctg atgtctccag cgactggcag gatcaagggc tggtggcgta
    22261 tgtcaatgtt gatcgcgaca gcgccagccg tctggggatc agcatggcgg acgtcgataa
    22321 cgccctgtac aacgcgtttg gtcagcggct gatttccact atttatactc aggctaacca
    22381 gtatcgcgtg gtgctggaac acaacactga aaatacccca ggcctcgcgg cgctggatac
    22441 cattcgcctg accagcagcg acggcggcgt ggtgccgcta agctcaattg ccaaaattga
    22501 gcagcgtttt gcgccgctct ccatcaacca tctggatcag ttcccggtaa cgactatctc
    22561 ctttaacgtg ccggataact attcgctggg cgatgcggtg caggcgatta tggacacaga
    22621 gaagacgctg aatctgccgg tggatatcac cacgcagttc cagggcagca ccctcgcctt
    22681 ccagtcggca ttgggcagca ctgtctggct gattgtcgcg gcggtggtgg cgatgtatat
    22741 cgtgctcggc attctgtacg agagctttat tcacccgatc accattctct cgacgctacc
    22801 caccgcaggg gtcggcgcac tgctggcgtt aatgattgcc ggtagcgagc tggatgtgat
    22861 tgcgattatc ggcattattt tgctgatcgg tatcgtgaag aagaacgcca tcatgatgat
    22921 cgacttcgcg ctggctgctg agcgcgagca aggcatgtcg ccgcgcgagg caatctacca
    22981 ggcttgtctg ttgcgttttc gtccgatcct gatgaccact ctggcggctc tgcttggcgc
    23041 actgccgctg atgttgagta ccggggtcgg cgcggaactg cgtcgtccgt taggtatcgg
    23101 catggtcggc ggtctgattg tcagccaggt gctgacgctg tttaccacgc ctgtgattta
    23161 tttgctgttc gaccgcctgg cattgtggac caaaagccgc tttgctcgtc atgaagagga
    23221 ggcgtaagtg aagttttttg ccctcttcat ttaccgcccg gtggcgacga ttttactgtc
    23281 ggtcgccatt accctgtgcg gcatactggg cttccgtatg ctgccggtcg ccccactgcc
    23341 gcaggtcgat tttccggtga ttatggtcag cgcctcgctg cccggtgcgt caccagaaac
    23401 aatggcgtct tccgttgcca cgccgctgga acgttcgctt gggcgcattg ccggggtcag
    23461 tgaaatgacc tccagcagtt cgctcggcag cacgcgcatt attttgcagt ttgattttga
    23521 ccgcgatatc aacggcgcag cgcgcgatgt gcaagcggcg atcaacgccg cgcaaagttt
    23581 gctgcccagc gggatgccca gccgtccgac ctatcgcaaa gcgaacccgt cggatgcgcc
    23641 aattatgatc ctgacgctaa catccgatac ttattcgcaa ggtgaactgt acgattttgc
    23701 ctcgacgcag ctggctccga cgatttcgca aatcgacggt gtcggtgatg tcgatgttgg
    23761 cggcagctcg ctacctgcgg tgcgcgtcgg gctgaacccg caggcgctgt ttaatcaggg
    23821 cgtctcgctg gacgacgtac gcactgccat cagcaatgcc aacgtgcgta aaccgcaagg
    23881 ggcgctggaa gatggcactc accgctggca gatccagact aacgatgaac tgaaaaccgc
    23941 cgctgaatat cagccgctga ttattcatta caacaacggc ggcgcggttc gtctgggcga
    24001 tgtagcgacg gtgaccgact cagtgcagga tgtgcgcaac gccgggatga ccaacgccaa
    24061 accggctatt ttgctgatga tccgcaagct gccggaagcc aatataattc agacggttga
    24121 cagcatccgg gcaaaattac cggagttgca ggagaccatt ccggcggcga ttgatctgca
    24181 aattgcccag gatcgctccc ccactattcg cgcctcgctg gaggaagtcg agcaaacgct
    24241 gattatctcg gtggcgctgg tcattctggt ggtcttttta ttcctgcgct cgggtcgcgc
    24301 cactattatt cccgccgttg cggtgccggt ttcgctgatt ggtacgtttg cggcgatgta
    24361 cctgtgcggt ttcagtctca ataatctttc gttaatggcg ctcaccattg ctactggttt
    24421 cgtggtggat gacgccatcg tggtgctgga aaacattgca cgtcatctgg aagcgggaat
    24481 gaaaccgttg caagccgcac tgcaaggtac tcgcgaagtc ggttttacgg tgctgtcgat
    24541 gagtctgtca ctggtggcgg tgttcctgcc gctgctgttg atgggcggat tgccgggccg
    24601 actgttacgc gagtttgccg tgacgctttc tgtcgccatt ggtatttcgt tgctggtttc
    24661 cctgacgcta acgccgatga tgtgtggctg gatgctgaaa gccagcaagc cgcgcgagca
    24721 aaagcgactg cgtggttttg gtcgcatgtt ggtagccctg caacaaggct atggcaagtc
    24781 gctgaaatgg gtgctcaatc atacccgtct ggtgggcgtg gtgctgcttg gcaccattgc
    24841 gctgaatatc tggctatata tctcgatccc gaaaaccttc ttcccggagc aggacaccgg
    24901 cgtgttgatg ggcgggatac aggcggatca gagtatttcg tttcaggcga tgcgcggtaa
    24961 gttgcaggat tttatgaaaa ttatccgtga cgatccggcg gtggataatg tcaccggctt
    25021 taccggcggt tcgcgggtga acagtgggat gatgtttatc accctcaagc cacgcgacga
    25081 acgcagcgaa acggcgcagc aaattatcga ccgtctgcgc gtaaaactgg cgaaagaacc
    25141 gggggcgaat ctgttcctga tggcggtaca ggatattcgc gttggtgggc gtcagtcgaa
    25201 cgccagctac cagtacacgt tgttatccga cgacctggcg gcactgcgcg aatgggagcc
    25261 gaaaatccgc aaaaaactgg cgacgttgcc ggaactggcg gacgtgaact ccgatcagca
    25321 ggataacggc gcggagatga atctggttta cgatcgcgac accatggcac ggctgggaat
    25381 cgacgtacag gccgccaaca gcctgttaaa taacgccttc ggtcagcggc aaatctcgac
    25441 catttaccag ccgatgaacc agtataaagt ggtaatggaa gtggatccgc gctataccca
    25501 ggacatcagc gcgctggaaa aaatgttcgt tatcaataac gaaggaaaag cgatcccgct
    25561 gtcgtatttc gctaaatggc aaccggcgaa tgccccacta tcggtgaatc atcagggatt
    25621 atcggcggcc tcgaccatct cgttcaacct gccgaccggg aaatcgctct cggacgccag
    25681 tgcggcgatc gatcgcgcaa tgacccagct tggtgtgcct tcgacggtgc gcggtagttt
    25741 tgccggcacg gcgcaggtgt tccaggagac gatgaactcg caggtgatcc tgattatcgc
    25801 cgccatcgcc acggtgtata tcgtgctggg tatcctttac gagagttacg tacatccgct
    25861 gacgattctc tccaccctgc cctcggcggg cgttggagcg ctgttggcgc tggagctgtt
    25921 caatgccccg ttcagcctaa tcgccctgat agggatcatg ctattaatcg gcatcgtgaa
    25981 gaaaaacgcc attatgatgg tcgattttgc gcttgaagcc caacggcacg gtaacctgac
    26041 gccgcaggaa gctattttcc aggcctgtct gctgcgtttt cgcccgatta tgatgactac
    26101 cctggcggcg ctgtttggcg cgctgccgct ggtattgtcg ggcggtgacg gctcggagct
    26161 gcgccaaccc ctggggatca ccattgtcgg cggtctggta atgagccagc ttctgacgct
    26221 gtataccacg ccggtggtgt atctcttttt cgaccgtctg cggctgcgtt tttcgcgtaa
    26281 acctaaacaa acggtaaccg agtaaatgac agatcttccc gacagcaccc gctggcaatt
    26341 gtggattgtg gctttcggct tctttatgca gtcgctggac accaccatcg taaacaccgc
    26401 gcttccctca atggcgcaaa gcctcgggga aagtccgttg catatgcaca tggtcattgt
    26461 ctcttatgta ctgaccgtgg cggtgatgct gcccgccagc ggctggctgg cggacaaagt
    26521 cggcgtgcgc aatattttct ttaccgccat cgtgctgttt actctcggtt cactgttttg
    26581 cgcgctttcc ggcacgctga acgaactgtt gctggcacgc gcgttacagg gcgttggcgg
    26641 tgcgatgatg gtgccggtcg gcaggttgac ggtgatgaaa atcgtaccgc gcgagcagta
    26701 tatggcggcg atgacctttg tcacactgcc cggtcaggtc ggtccgctgc tgggtccggc
    26761 gctcggcggt ctgctggtgg agtacgcatc gtggcactgg atctttttga tcaacattcc
    26821 ggtgggaatt atcggcgcga tcgccacact gatgttaatg ccgaactaca ccatgcagac
    26881 gcggcgcttt gatctctccg gctttttatt gctggcggtt ggcatggcgg tattaaccct
    26941 ggcgctggac ggcagtaaag gtacaggttt atcgccgctg gcgattgctg gcctggtcgc
    27001 tgttggcgtg gtagcactgg tgctttatct gctgcacgcc agaaataaca accgcgccct
    27061 gttcagtctg aaactgttcc gcactcgtac cttttcgctg ggtctggcgg ggagctttgc
    27121 cggacgtatt ggcagtggca tgttgccctt tatgacaccg gttttcctgc aaattggcct
    27181 cggtttctcg ccgtttcatg ccggactgat gatgatcccg atggtactcg gcagcatggg
    27241 aatgaagcga attgtggtac aggtggtgaa tcgctttggt tatcgtcggg tactggtgtc
    27301 gaccacgctg ggtctgtcgc tggtcaccct gttgtttatg accactgctc tgctgggctg
    27361 gtactacgtt ttgccgttcg tcctgttttt acaagggatg gtcaactcga cccgtttctc
    27421 ctccatgaac accctgacgc tgaaagatct cccggacaat ctggcgagca gcggaaacag
    27481 cctgctgtcg atgattatgc aattgtcgat gagtatcggc gtcaccatcg ccgggctgtt
    27541 gctggggctt tttggttcgc agcatgtcag cgtcgacagc ggcaccacac aaaccgtctt
    27601 tatgtacacc tggcttagca tggcgtttat catcgccctt ccggcgttca tctttgccag
    27661 agtgccgaac gatacgcatc aaaatgtagc tatttcgcgg cgaaaaagga gcgcgcaatg
    27721 aagttctggc gacccggtat taccggcaaa ctgtttctgg cgattttcgc cacctgcatt
    27781 gtcttgctga tcagtatgca ctgggcggtg cgtatcagtt ttgagcgtgg ctttattgat
    27841 tacatcaaac acggcaatga acagcgatta cagctgttaa gtgatgcgct tggcgagcag
    27901 tatgcgcagc atggcaactg gcgcttcctg cgcaacaacg atcgctttgt ctttcagatc
    27961 ttgcgttcat ttgaacacga taattcggaa gataaacccg gcccgggtat gccgccgcac
    28021 ggctggcgta ctcaattctg ggtggtcgat caaaacaaca aagtgctggt tggtccgcga
    28081 gcgccgattc cacctgacgg tacacggcga cccattctgg tcaacggtgc ggaagtgggt
    28141 gcggtgattg cctcccctgt tgagcgactg acccgcaata ctgatatcaa tttcgataaa
    28201 caacagcggc aaaccagctg gctgattgtc gccctggcaa cgttactcgc ggcgctcgcc
    28261 acctttctgc tggcgcgtgg tctgttggcc ccggtcaaac ggctggtgga cggcacgcac
    28321 aaactggcgg cgggcgattt cacaacccgc gtgacgccca ccagtgaaga tgaactgggc
    28381 aaactggcgc aggacttcaa ccagctcgcc agcacgctgg agaaaaacca gcaaatgcgg
    28441 cgcgatttta tggccgatat ttctcacgaa ctgcgtacgc cattagcggt gctgcgcggt
    28501 gaactggaag ccattcagga tggcgtgcgc aaattcacgc cggagacggt ggcgtcttta
    28561 caggcggagg tcggtacact gaccaaactg gttgacgatc ttcatcagtt gtcgatgtct
    28621 gatgaaggcg ctctcgccta tcaaaaagca ccggtagatt tgatcccact gctggaagtg
    28681 gcgggcggcg catttcgcga acgatttgcc agccgtggcc tgaaactgca attttccctg
    28741 ccagacagta ttaccgtatt tggcgatcgc gaccgtttaa tgcagttatt caataactta
    28801 cttgaaaaca gcctgcgcta cactgacagc ggcggcagcc tgaaaatctc tgccgagcag
    28861 cacgacaaaa cggtgcgact gacctttgcc gacagcgcgc cgggcgtcag tgacgatcag
    28921 ctacaaaaat tgtttgaacg tttttatcgc accgaaggtt cccgcaaccg agccagcggc
    28981 ggttccgggc tggggctggc gatttgcctg aacattgttg aagcacataa tggccgcatt
    29041 attgctgccc attcgccttt tggcggggta agcattacag tagagttacc gctggaacgg
    29101 gatttacaga gagaagtatg accgagttac caatcgacga aaacacaccg cgtattttga
    29161 tcgtggaaga tgaaccgaag ctgggacagt tgctcattga ttatctgcgt gctgcgagct
    29221 atgcgccgac gcttatcagc cacggcgatc aggtactgcc gtatgtgcgc cagacaccac
    29281 cggatctgat cctgttggat ctgatgctcc ctggcaccga tggcttgacg ctgtgccgag
    29341 aaattcgtcg tttttctgac attcctatcg tgatggtgac ggcaaaaata gaagagatcg
    29401 accgcctgct cggactggag attggcgcag atgattatat ctgtaagccg tacagcccac
    29461 gggaagtggt agcgcgcgtc aaaaccattt tgcgccgttg caaaccgcag cgtgagttgc
    29521 agcaacagga tgctgaaagc ccgttgatta tcgacgaagg tcgttttcag gcttcatggc
    29581 gcggtaaaat gcttgacctg acgcctgcgg aatttcgtct gctgaaaacg ctctctcatg
    29641 aaccaggaaa agtgttctcc cgcgagcaat tgctcaatca tctttatgac gactaccgcg
    29701 tagtaaccga ccgcaccatc gacagccaca ttaaaaacct gcgccgcaag ctggaatctc
    29761 tcgacgccga acagtccttt atccgtgccg tttacggcgt cggttaccgc tgggaagccg
    29821 acgcctgccg catcgtttaa catttttacc tgccggagaa ggcattcacg ccgcatccgg
    29881 caacataatc ccacgcatgg tcagcaaact gacattatct ctccgccctg gcaggcacca
    29941 gaaaatcgct catactttaa tcggtaaaca gcacctttag atgctgtttt cgatacgcaa
    30001 tttcaatcaa ggagtcatta tggctggttg gtttgaactc agtaagagca gtgataatca
    30061 attccggttt gtgctaaaag cgggcaatgg tgagactatc ctcaccagcg agctgtatac
    30121 ctcaaaagcc tctgcggaaa agggcatcgc gtcggtgcgt agcaacagcc cgcaagaaga
    30181 acgctatgag aaaaaaacgg caagcaacgg caaattctat ttcaatctga aagccgccaa
    30241 tcatcaaatt atcggctcca gccaaatgta cgccaccgcg caatctcgtg aaaccggaat
    30301 tgcctccgtt aaagccaatg gcacaagcca gacggtgaaa gacaatacgt aattacgatg
    30361 ccgggcgcgt gttgttggcg tccggcgctt taccaactcc cccctacagc gctacaatgc
    30421 ccgcccttaa agtgggggca ctcccctaac cgcttcatca ggtgaagcgg atctgacctg
    30481 tcatcagaac gagagaatta tgtttaaacc ggaactcctt tccccggcgg gaacgctgaa
    30541 aaatatgcgt tacgctttcg cttatggcgc agatgctgtt tatgcgggcc agccgcgtta
    30601 ctccctgcgt gtgcgcaaca acgaattcaa ccacgaaaat cttcaactcg gcattaacga
    30661 agcccacgcg ctggggaaaa agttttatgt cgtggtcaac attgcaccgc acaacgccaa
    30721 gctgaaaacc tttatccgtg acctgaaacc ggtggtggaa atggggccgg atgcgctgat
    30781 tatgtccgat ccagggctga ttatgctggt gcgtgagcac ttccctgaaa tgccgatcca
    30841 tctctcggta caggctaacg ccgtgaactg ggcgacggtg aaattctggc agcaaatggg
    30901 cctgacccgc gtgatcctct ctcgcgagct gtcgctggaa gagattgaag agatccgcaa
    30961 tcaggtgcca gatatggagg tagagatctt cgttcacggc gcgctgtgca tggcctactc
    31021 cggtcgctgc ctgctctctg gctacatcaa caagcgcgac ccgaaccagg gcacctgcac
    31081 caacgcctgc cgttgggagt acaacgtcca ggaagggaaa gaagatgacg ttggcaacat
    31141 cgtacacaag tacgagccga ttccggtgca aaatgttgag ccgacgctgg gtatcggcgc
    31201 gccgaccgac aaagtgttta tgatcgaaga agcccagcgt ccgggcgagt atatgaccgc
    31261 gtttgaagat gagcacggca cttacatcat gaactcgaaa gatctgcgtg ccatcgccca
    31321 cgttgaacgc ctgaccaaaa tgggcgtgca ttcgctgaaa atcgaaggcc gtactaaatc
    31381 tttctactat tgcgcacgca ccgcgcaggt ttatcgtaaa gctatcgatg acgccgctgc
    31441 gggcaaaccg ttcgatacca gcctgctgga aactctggaa ggtctggcgc atcgtggcta
    31501 taccgaaggt ttcctgcgtc gtcatactca cgacgattat cagaactacg aatacggtta
    31561 ttcagtttct gaccgccagc agtttgttgg tgagtttacc ggtgagcgca agggcgacct
    31621 cgcggcggta gcggtgaaaa ataaattctc cgttggcgac agccttgagc tgatgacgcc
    31681 gcaagggaac attaacttta cccttgagca gatggaaaac gccaaaggca aagcaatgcc
    31741 ggtcgcaccg ggcgatggtt atactgtgtg gatcccggtc ccgcaggatc ttgagctcaa
    31801 ttacgcgctg ctgatgcgta atttctccgg ggaaaccacg cgtaaccccc acggtaagtg
    31861 attaatttcg attatttttc ccggatggaa aattcttaga aaccgatcac atacagctgc
    31921 atttattaag gttatcatcc gtttcgctga aaaacataac ccataaaatg ctagctgtac
    31981 caggaaccac ctccttagcc tgtgtaatct cccttacacg ggcttatttt ttacgcgtaa
    32041 gccctatccc tggtcaccgt cttccattga ccacatcgat agaatctccc ttcatagcac
    32101 gatgcctttc acgtaacggc atcgtgctcg cacaggttcc ggctaagcac aaccagaacg
    32161 cgcatgtttg acgcttacca aaaaatattc tcactctcca catttgaatg tcagacgagc
    32221 gacgccatgt aatcctgcac cttctgtctt caggtcaact atctgcattt ttttgccctg
    32281 agtaacacag aaatgagctg catcattttt tactatattt tctgcaccag aaattctgcc
    32341 cctggctaaa gaagcttcgg cttcggtgta gtattggtta tcgagtttac gctgaatatt
    32401 acttttatat gcaagaccaa atttaccgat acttgtctca tcattatgca cagcacaccc
    32461 agacataaga aaaacactaa ttaatgatat agcagctatc tttttcatct taccttcccc
    32521 cattaaatac caacgacacg ctttggtgtt aaaatataat aatggcatga ttattataat
    32581 tgaataggat tataataaat gttctgtaca acatttccta cataagtagg aattacatac
    32641 acggatgccc ttccggataa ccccatgggg ggttaatata tttttaatag tatattgaag
    32701 atgccactgt ttagttgaat attaggtata tgctcttttt tgaaatttac cggtggctac
    32761 cgttaacatt cactgtcccc attgcaagct cctggtggta accactgaat cctctatact
    32821 tgaactgact ttttatcctc cgactttcat cctgttctga ctccaccttt tcttttctgc
    32881 tctacactat ctacagacca atcataaagg cacatacgat catggcagaa tttcccgcca
    32941 gcttactgat tcttaatggc aaaagtactg acaatttacc attgcgcgaa gcaattatgc
    33001 tgttgcgtga ggaaggaatg acgatccatg tgcgggtcac ctgggagaaa ggcgatgccg
    33061 cacgatatgt agaggaggcc cggaagttgg gcgtcgcaac ggtgattgcc ggtggtggcg
    33121 atggcaccat taatgaagtt tctacggcgt tgattcagtg tgagggggat gacatacccg
    33181 cgctaggaat tttgccatta ggaaccgcca atgattttgc caccagtgta aggattcctg
    33241 aggcactgga taaggcgctg aaactggcaa ttgccggtga cgccattgcg atagatatgg
    33301 cgcaggtcaa caaacaaacc tgttttatta atatggcgac aggcggattt gggacgcgta
    33361 ttaccacaga aacgccggaa aaattaaaag ccgcgctggg tggcgtctct tacatcattc
    33421 atggcttaat gcgcatggat actctgcaac cggaccgttg tgagatccgc ggtgaaaact
    33481 ttcactggca aggtgacgcc ctggtcattg gtattggtaa cgggcgtcag gccggtggcg
    33541 gtcagcaatt gtgcccgaac gcgttaatta acgatggctt gctgcaactg cgcattttta
    33601 ccggcgatga aattcttccg gctctcgtat caacattaaa atctgacgaa gataacccga
    33661 atattatcga aggcgcttcg tcgtggtttg atatacaagc cccacacgaa atcactttta
    33721 atcttgatgg cgaaccgttg agcggacaaa actttcatat tgaaatactt ccggcggcgt
    33781 tgcgttgtcg attaccacca gattgcccat tgttgcgtta atcacactat tctctcttga
    33841 accagggaga atccgtaatg ccggatgcgg tgtaaaaact ttatccggca tacagagcaa
    33901 tactacaccg taattaattt cacccgtgtc ttctgcaatg ccagtttatc cacctctgac
    33961 acggcatcat cggtaataat aatgtcaatt ttttcgattg gcagtacctg attaaaaccg
    34021 cgacgattaa atttcgatga atcgagaacg gcaatcactt tatttgcggc tgtaaccatc
    34081 gccccgctaa tcgaataacc ttcattaaag gtcgtaatac cattaaccgc atcaatacca
    34141 tcagcaccga caaacattaa atcggcatta atatcctgca atgaacgctc ggcaatggaa
    34201 ccatgcatcg agcgtgtttt atggcggacg gtcccaccac agacgaccag agtaatgtct
    34261 ttattttcgg aaagggcaaa tgctgccggg agactgttgg taatcaccgt gatatttttg
    34321 gcggtcatta atccttcggc gataagcatt gtcgtacttc cgctgtcgag aataacggtc
    34381 atcccttcgt ggatcatttt gactgccgcc tgcgctattc tgttttttgg cgcgctggcg
    34441 agctgaaatc gctctttaaa cccaacttcc tgggtctcgg tttcactatt accggacatt
    34501 attttcgccg caccgccatg aaagcgcgta accacgcctt tttgttcgag aaagcgcaaa
    34561 tcggcacgga ttgtcgcttc cgaggcagca aatactcccg ccagatcctg aacaagcacg
    34621 gttccctgtt cattcactaa ttggatgatc ttattccttc gctcgaatga attcatcgtc
    34681 atttacccat attcaattgt ggctagtgta aacgaagggg gaccattggt gaatgatctg
    34741 ttttgcacaa taccgggcca gcatcacgct ggcccgcggt ttcagggaat gagcaacact
    34801 ttgcccggca tagcattacg agcgatgtca cgcaccgcct gggcgaagct ttcaaagctt
    34861 ccacggtgag cgattaatgg ctccaggctt aacttacgtt ctgtcagcaa ccggctcgcc
    34921 gtttcccact cctgccccgg ccaagggctg gagtagttca tccagctgcc gataaccgtc
    34981 agctctttac gtaatatttt gccaaacgtt gtcgatgtta aatgcagatc ctgatgcaac
    35041 atgcccacca gcgccagctg ggcatgaggc ccggcaatct ctaccgccag ttcgacggtt
    35101 ttcgggacac cagccgtctc gaggataagc tgattaaagc gcagctcgcg taaaacgccc
    35161 tgcatttgcg gcgcgctcat ttcaaggctg ttaaatgttt gcatcgcacc gaaaaatttt
    35221 gccagtgcca gtttttctga gctaatgtcg atagccgtca cactctttgc tcccagcgcg
    35281 acagcgcact gaatagccag caggccaatg gttccggcac caataataat aacgttttta
    35341 ttctcacaac cttgcgctaa atgaaaagca tgcaggccaa cggtaatcgg ctcaataaaa
    35401 gccccatcct caataggcat atccgtgggt agagcaaaga cattttttcg cttaacgaca
    35461 atatattcag caaatccacc atcacgccgc gagccaataa aatcatattt tgcgcactgg
    35521 gaataaaacc ctttcaaaca ctctggacaa gtaaaacagg gtaataacgg cacacaggca
    35581 accgcatcgc caggatgtaa atcatcaaca ccggatccca cagcatcaat atagccgcta
    35641 aattcatggc ctaacgttat tggataataa tgtgcaccat ttttaaaaat tctgggtaaa
    35701 tcggaaccac ataatcccga gctggcaatt ttgacccgca cctcatcctg atgtttaatt
    35761 tcaggaatga cgctttctgc aacgcgcacg ataccatcag tatcattcac cactgatttc
    35821 ataaaaactc ctgattgtta agggggatta cctccccctc aggtaaaaat tattctgcga
    35881 gaacggcttt ctcttgttta ataaaaccac gcgctctacg ccaggtcatg aaaataccgg
    35941 tcagataaat tgcgccgata ataatgaaac cgggaatatt ttgcggggag aaaacctgaa
    36001 tcagtaacca ggtaatggga gaaccgccct gatccattga agccaccata cccccggctt
    36061 ttaacgcccc agcattagcc gccagttggg tgtgcaaacc aatagtttgc gtcgcgatcc
    36121 acagggtgat gctcataatg atgacacccg agattaaggt gcggaacaga tttccacgat
    36181 gcacggcaac cgccatcgcc acgaagaagc cgatagttgc aagatcgcca aacggcagca
    36241 cctgattacc cggaacacaa acagcaatta aaatggtgag agggataaaa atcaggcttg
    36301 ccgataccac cgccgtatgc cccagcagca acgccggatc aaggccaatc aggaactcct
    36361 gaccgccgaa cttcgcctgt aaacgactac gggcctgctt agcgataggc gttaaaccat
    36421 ccatgatggg tttaatcact cttggcatca gcagcataac tgccgccgtt tttaccgcca
    36481 gctgcaatac acctttgaca tcgtaacccg cgaggatgcc gataatcagc cccatcacaa
    36541 aacccacggt gacaggctcg ccaaacggac caaatttgcg ctgaatatcg tcggcgctaa
    36601 atttaatacg gttaacgcct gggattttct cgatgatagc atccaccagc accgcaattg
    36661 gccccagata cgccgacgta ccgtgcggaa tagcaatgcc ttccagctca aagaaatttc
    36721 gggtatcgcg ggcaaaccag tcgccgagct tataaacaaa cgccgcgtga attaccacac
    36781 ccgccatccc tatcatccat gaaccggttg ccagatgcag caatgcgccg gtgaaggtca
    36841 tatgccagat attccagata tcaacattta ccacccgcgt catacgggtc agtagcatcg
    36901 ccacgttaac cagaatcgca atcggaatcg ccaccagcgc aatttgcgac gcccaggtca
    36961 ttggtgaaga gcccggccaa ccgacatcga ccacatgcag attcaggtcg aaattttccg
    37021 ccatcgcttt cgccgccgga ccaatggaat ccagcattaa gccaatcaca aggccaatgc
    37081 caacaaagcc aatcccgata tgcagacccg ctttaaagca atcgcctgcc ttcatgccta
    37141 atattttaga aaaaataatg atgacaatcg gcagcatcac cgtagggccg aggtcgagaa
    37201 tataacgcat gacttctgaa aacataggtc acccctgtaa gatagtcaga attttatttt
    37261 gtaatgcttc gataccgaca ccagaaacaa aaggcatgcc gtgaactaac ggaatatcgc
    37321 caaaactacg gtcaactttg gcggtagtac atatcaaatg cacaccatcc atataggttt
    37381 ctatttcatt aacccgacac tggattaatt caacaggaat attatgactc tgacacaact
    37441 ctttaatttc ttccgccgcc atcgtagagg tcgcaaccgc gcctccgcaa gcgacaataa
    37501 tcttgcgttt cataaatagt cctttttatt gttacagagg gatttattcg tctgaatcta
    37561 aaacatactt tgtgaagtat tcctttaact gggtttcagg aagagtgatt agtgtctcga
    37621 cgatatcggg ctgttgtaac ttgccaaata aacagcgtaa aagtttcaat tgctgctgcg
    37681 gattttccac aatcaacgcg ataaccaacg ataccgccac gtccttatca tcatccgctt
    37741 gctgaaaatg aactttattt gttggcctta acagataaat ggctgacgac ttagcatgaa
    37801 tcgcctcaca atgcggtatt gcgatggcgt gctgctcaag cattatcccg gtagggaatt
    37861 ctgcttctct ggcaattaat gcctgtggcc aggtatcatg aaccacacct ttcgcgagca
    37921 tctcattacc gatatgggtt aaaacttcgc tacgatcgac aaaagaaatt ccgctacgaa
    37981 caaacaggtt agtcatatac cgtccttatt ccgcacagcc gtagcgatag gcgcgcaaaa
    38041 catcataaat tttatccata atcagctgat gcggtattgc tgataattcc ccggactgaa
    38101 tgcgttcaaa ttgtttgggg agatactgac taatcatgcc cagtgggatg tccacgcctt
    38161 gcagattcaa catcatcgtt tcgacgctat ttttaatccg actatgcggc cagtaataac
    38221 gaatacgatc cgacaggctg taacgaatat ccagtaatga atcgttaaaa cccgtacgat
    38281 aatatttttt ccagtattgc ggttcgtcga gcatcacttc ttcaattaca gccaggcaac
    38341 cgctgcgatt ttcgggggcg ataatttcct gctcaatttg tgctaacgca aatatcgcct
    38401 cacgtagagc aaaggttaat gctggcccga ctttcaaaat tgcaaagtga tcgcggacta
    38461 attcccaata agccgtccgg gtctggtaat cggtagaatg tgcttcataa accattcggg
    38521 tgttttctat ccattgcgcc agcgcctgcg cttcttgcgg ctgataatgg ataatattgc
    38581 tgtgatcaaa ttccacaccc ggctgcacca cgatggcaat cacgcgtgtt aacgcctctg
    38641 tcagcccacg agcaataaag gccttttgat gcgtacgtaa agtattggcg gcatcttcaa
    38701 cccgggtaat gtgtactgac tgaatggcgc tggcctcacc gcccggaacc ggcacttcgg
    38761 tgccaatgac atagctcagt tgctcacgct ggcaatctgt cgccacactt tccgcagcaa
    38821 agcaaagcac agcagctcgt tccgcaaccg tttctggtgc taacggtatg ggatcccccg
    38881 cgcaggatat tgacgcatca agatgaattt tactgaagcc agcacgaaca tatgccttta
    38941 ccagctcgac ggatttttcc atcgccgcat tcgcattttc ttgctgccag cagtttggcc
    39001 ccagatgatc gccgccgaga ataatgcgct cgcgcgcaaa tcccacttta tcggcaatcg
    39061 taaaaacaaa ttcgcgaaag tctgccggtg tcattccggt ataaccgcca aattgattga
    39121 cctggtttga cgttgcttca atcagcactt tgcgcgtgct gttgcgatca aatgccagcg
    39181 ccgcttcgat aaccaacgga tgggcagaac agactgagca tatgccgata tgttcaccag
    39241 ctttatgccg ggcaattaac gttttcatgt tttttccttg ttaaatggca ggtgcgttat
    39301 gccctgccct cgcagccaca atcggcaatc actttgctca ccacatcgcg cattgcggat
    39361 ttagccgact gcaaataatc ccggggatcg gtcgcttcgg ggtgctcggt caggtaattt
    39421 ttcaacgcct gcgagaaggc atttttcagc tccgttgcaa cgttgatttt gcatatcccc
    39481 agtttgatgg tttgctgaat atccttagtc gataaccctg acgcgccatg cagcaccagc
    39541 ggtaagttca cccactggcg aatgttctcc agccgagaaa aatcaagcgc cggtgcgctg
    39601 gcatacatac catgagccgt gccgatggcg accgccaggg aatcaattcc ggttgcctcg
    39661 gcaaattcac gcgcctgaat ggggttggtg tacaacgcat cggcttcatt gacttgcaca
    39721 tcatcttcct ggccgccaag ttgccccagc tccgcttcga cgctgacatc aaagccatgg
    39781 caaaaatcca ccacctcttt gacccgtgaa atattttgcg caaaaggcaa atgcgaggcg
    39841 tcaatcatga ctgagcgcac gccagaacga accttctgag cgatatcgtc aaatttcgtg
    39901 tgatggtcga gatgaatcgc cagtggatgg tgatattgct tcgccatcgc gctgaccagc
    39961 gccaacaaat tttctgtacc tgcatgagta aatgtgccgg gcgttccggc gatgatgacc
    40021 ggcgcatgca tgctggcagc ggtttctacc accacttgca tcgtttcgag attgtgaata
    40081 ttgaatgccg gaaccgcata accgccgcgc tgcgcgttgt tcagcatctg ctttgtcgat
    40141 accacgtaca ttttcatatc ctgtcgtttg ctttcgattt caa
//
LOCUS       DADXDL010000036        39611 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.036, whole genome shotgun sequence.
ACCESSION   DADXDL010000036 DADXDL010000000
VERSION     DADXDL010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39611)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39611)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39611
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.036"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            172..1026
                     /locus_tag="IRB70_002197"
     CDS             172..1026
                     /locus_tag="IRB70_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000275530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose bisphosphate family class II aldolase"
                     /protein_id="HBC0632107.1"
                     /translation="MYIISSKNMLKKAQSEGYAVPAFNIHNLETLQVVVESAAQLRSP
                     VMLAGTPGTYRYGGVGSLISLVQSLAREYNLPLVLHLDHHEECDDIFNKVRAGIRSVM
                     IDGSHLPFEDNIARVQEVTAFCHRFDVSVEAELGRLGGQEDDLLVDEKDSAYTSPAAA
                     AEFVQRTQIDSLAVAIGTAHGLYAHEPRLDFVRLEQIRQLVEIPLVLHGASGLSEQDV
                     QLCIRHGICKVNVATELKIAFADALKGYFYNNPAANDPRHYMQPAKAAMKEVVTRIIG
                     VCGSEGKI"
     gene            1062..1952
                     /locus_tag="IRB70_002198"
     CDS             1062..1952
                     /locus_tag="IRB70_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBC0632108.1"
                     /translation="MKNIKLLGSAMLVSLALFSQSSLAKEYKIGASLLTQQHPFYIDL
                     ANAMKEEAKKDNVNLSVSIANQDLNKQLSDVEDFITKKVDAIIISPVDSKGVQAAIIK
                     ADKAGIPVITVDVAAEGVPVVSHVATDNYAGGVEAGKLMGKLLNGKGTVAIISYPALQ
                     SVVARVDGFKKGLSETPDIKIVAEQPGITRAEALTTAQNIMQANANLNGLFGFGDDAA
                     LAAVIAAKSAHNDNIKIIGFDGMKEARDAVDSEKTFAAVIRQYPDQMGAKAIDAAVDH
                     LNGKPVEKMIPVQPGVYTGK"
     gene            2013..3512
                     /locus_tag="IRB70_002199"
     CDS             2013..3512
                     /locus_tag="IRB70_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBC0632109.1"
                     /translation="MTDVILDVSHIAKTFGHVQALKNITLSLRKGRVHTLLGENGAGK
                     STLMKILAGVYPPTQGTITLRGETITINNPQHSRQLGIAIIFQELSLSNNMTVAENIY
                     ANNEPRRFGIINDKKMLADCQNLLAELGIPLDPLEMVGNMSMAHRQLVEIAKALSYAA
                     DVVIMDEPTSSLSDNEAEILFNIIEKLKQRGCAVIYISHRMDEIMRISDDISVIRDGE
                     YIATHEKKNSDIQHLIAQMVGREMKNIWPARLGEKPDENVPAKLEVKKLSHPSLFKEV
                     SFAVRPGEVLGFFGLVGAGRSDVMKALFGLVSYHGTVLIDGKEVRIANPKQAIDHGIA
                     FVTENRKEEGLVLMHDVNMNTHHVAFQYNASRMGLINHRQEEAKTLQSIARMNTKVSS
                     VHQAVGALSGGNQQKIVLSKWLEKTPRILLLDEPTRGVDVGAKFEIYNVIRQLTAAGT
                     AIILVSSELPEVMALSDRLVVMRNKTIADIYSCENLTQTQVMTAATGVR"
     gene            3513..4502
                     /locus_tag="IRB70_002200"
     CDS             3513..4502
                     /locus_tag="IRB70_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001525780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0632110.1"
                     /translation="MTEKTLASPKPSEIPIANNFKKVFRQYGGILSGMVVLIILFSFI
                     NDSFFTANNITNIILQVSIIAITAYGMTYVLLLGDIDLSVGSTIALIGTFAALGASWG
                     IPFILLVPLSIIAALALGMINGGLTAIAGIPSFIVTVATMGIFRGIAYIVTDGMPIMI
                     KDDAFLALGNGEFLYIPIPIWILIILLLINHFILTKTTFGRKIYITGGNKEAAVYSGI
                     NVTRLKIKVFMITAVLAGISGMILASRLYSGQPNSALSYELDAIAAAVLGGTSLNGGY
                     GTVVGTVIGALTIGVINNGMNLMNVPYFYQMVVKGLVILVAVYFDVRNKRKRS"
     gene            4524..5486
                     /locus_tag="IRB70_002201"
     CDS             4524..5486
                     /locus_tag="IRB70_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000048618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBC0632111.1"
                     /translation="MSKVFTIGEILVEIMASKIGQPFDQPGIWNGPYPSGAPAIFIDQ
                     VTRLGVPCGIISCVGNDGFGDINIHRLAADGVDIRGISVLPLEATGSAFVTYHNSGDR
                     DFIFNIKNAACGKLSAQHVDENILKDCTHFHIMGSSLFSFHMVDAVKKAVTIVKENGG
                     VISFDPNIRKEMLDIPEMRDALHFVLELTDIYMPSEGEVLLLSPHSTPERAIAGFLEE
                     GVKEVIVKRGNQGASYYSANEQFHVESYPVEEVDPTGAGDCFGGAWIACRQLGFDAHR
                     ALQYANACGALAVTRRGPMEGTSRLAEIEAFIQRHDMSIREAAQ"
     gene            5483..6529
                     /locus_tag="IRB70_002202"
     CDS             5483..6529
                     /locus_tag="IRB70_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBC0632112.1"
                     /translation="MKNEIWSWIGDLSQVAGIKHYELRSGRAKGTEAFDVRTGAGLAF
                     TVVKDRALDIAWASYKDTALSFITPNGIVAPAFFESQGNGFLRSFYAGLLTTCGLSYI
                     GTPCEDNGETLGLHGRLAATPAEEVGYRTERTDDGIEFVINGKVRETRLFGENLTLER
                     TIRCRYGENVLRIEDKVTNHGFTRQPLQILYHFNYGWPLLSPQAEILLSAKSVTPRTP
                     HAAEGLTSHLEICTPQPGFDEQVYYLTLNSDSQGMSKVALVNAELGWGIYEKFDTMQL
                     PNFIQWKNLGAGEYVMGLEVSNSFPDGRDKERAQGRLPFIEPGETKTYCFELGIVDGD
                     AEISALKAEIASYR"
     gene            complement(6621..7970)
                     /gene="accC"
                     /locus_tag="IRB70_002203"
     CDS             complement(6621..7970)
                     /gene="accC"
                     /locus_tag="IRB70_002203"
                     /EC_number="6.3.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009483995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBC0632113.1"
                     /translation="MLDKIVIANRGEIALRILRACKELGIKTVAVHSSADRDLKHVLL
                     ADETVCIGPAPSVKSYLNIPAIISAAEITGAVAIHPGYGFLSENANFAEQVERSGFIF
                     IGPKAETIRLMGDKVSAIAAMKKAGVPCVPGSDGPLGDDMDKNRAIAKRIGYPVIIKA
                     SGGGGGRGMRVVRGDAELAQSISMTRAEAKAAFSNDMVYMEKYLENPRHVEIQVLADG
                     QGNAIYLAERDCSMQRRHQKVVEEAPAPGITPELRRYIGERCAKACVDIGYRGAGTFE
                     FLFENGEFYFIEMNTRIQVEHPVTEMITGVDLIKEQLRIAAGQPLSIKQEEVHVRGHA
                     VECRINAEDPNTFLPSPGKITRFHAPGGFGVRWESHIYAGYTVPPYYDSMIGKLICYG
                     ENRDVAIARMKNALQELIIDGIKTNVDLQIRIMNDENFQHGGTNIHYLEKKLGLQEK"
     gene            complement(7981..8451)
                     /gene="accB"
                     /locus_tag="IRB70_002204"
                     /gene_synonym="fabE"
     CDS             complement(7981..8451)
                     /gene="accB"
                     /locus_tag="IRB70_002204"
                     /gene_synonym="fabE"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBC0632114.1"
                     /translation="MDIRKIKKLIELVEESGISELEISEGEESVRISRAAPAASFPVM
                     QQAYAAPMMQQPAQSNAAAPATVPSMEAPAAAEISGHIVRSPMVGTFYRTPSPDAKAF
                     IEVGQKVNVGDTLCIVEAMKMMNQIEADKSGTVKAILVESGQPVEFDEPLVVIE"
     gene            complement(9317..10147)
                     /locus_tag="IRB70_002205"
     CDS             complement(9317..10147)
                     /locus_tag="IRB70_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000838295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632115.1"
                     /translation="MKSLFNRLTGKAVSRTAFVEHLGHEVVQHHPNWKVMISTDHKLM
                     RIDTGHQTVEITLDDAYKRYQAAPDPLEEVAADMLKQLAEMLPTGRCIVPVIKEKAWL
                     DTVRQQLSQYESDPEILNASLDFAWEDFNDELIILFAEDGSETMRYLMRYEVTIDREQ
                     AINNLKQILPEVSAEIVDTGANAGKVAVISAGGTYEPSLMLIDDLWVQSPDPECGDLL
                     VTVPSRGKLFFTYNDQPANLSALRQLTEQCFREDDHPLTTQIFIRRNGHFYPWVETLH
                     "
     gene            complement(10184..11158)
                     /locus_tag="IRB70_002206"
     CDS             complement(10184..11158)
                     /locus_tag="IRB70_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBC0632116.1"
                     /translation="MQALLLEQQDGKTLVSVQTLDESRLPEGDVTVDVHWSSLNYKDA
                     LAITGKGKIIRNFPMIPGIDFAGTVRTSEDPRFHAGQDVLLTGWGVGENHWGGLAEQA
                     RVKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVG
                     STAVALLHKLGYQVVAVSGRESTHEYLKSLGASRILPRDEFAESRPLEKQVWAGAIDT
                     VGDKVLAKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPARRA
                     QAWQRLVADLPESFYTQAAKEISLADAPKFAEAIINNQIQGRTLVKVN"
     gene            11310..13250
                     /gene="csrD"
                     /locus_tag="IRB70_002207"
     CDS             11310..13250
                     /gene="csrD"
                     /locus_tag="IRB70_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase E specificity factor CsrD"
                     /protein_id="HBC0632117.1"
                     /translation="MRLTTKFSAFVTLLTGLTIFVTLLGCSLSFYNAIQYKFSHRVQA
                     VATAIDTHLVSNDFSALRPQITELMMSADIVRVDLLHGDKQVYTLARNGSYRPVGTND
                     LFRELSVPLIKHPGMSLRLVYQDPMGNYFHSLMTTAPLTGAIGFIILMLFLAVRWLQR
                     QLAGQELLETRATRILNGERGSNVLGTIYEWPPRTSSALDTLLCEIQNAREQHSRLDT
                     LIRSYAAQDMKTGLNNRLFFDNQLATLLEDQEKVGTHGIVMMIRLPDFNMLSDTWGHS
                     QVEEQFFSLTNLLSTFMMRYPGALLARYHRSDFAALLPHRTLKEAESIASQLIKAVDT
                     LPNNKMLDRDDMIHIGICAWRSGQDTEQVMEHAESATRNAGLQGGNSWAIYDDSLPEK
                     GRGNVRWRTLIEQMLSRGGPRLYQKPAVTREGRVHHRELMCRIFDGNEEVSSAEYMPM
                     VLQFGLSEEYDRLLISRLIPLLRYWPEENLAIQVTVESLIRPRFQRWLRDTLMQCEKS
                     QRRRIIIELAEADVGQHISRLQPVIRLVNALGVRVAVNQAGLTLVSTSWIKELNVELL
                     KLHPGLVRNIEKRTENQLLVQSLVEACSGTSTQVYATGVRSRSEWQTLIQRGVTGGQG
                     DFFASSQPLDTNVKKYSQRYSV"
     gene            13555..14598
                     /gene="mreB"
                     /locus_tag="IRB70_002208"
     CDS             13555..14598
                     /gene="mreB"
                     /locus_tag="IRB70_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000913396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreB"
                     /protein_id="HBC0632118.1"
                     /translation="MLKKFRGMFSNDLSIDLGTANTLIYVKGQGIVLNEPSVVAIRQD
                     RAGSPKSVAAVGHDAKQMLGRTPGNIAAIRPMKDGVIADFFVTEKMLQHFIKQVHSNS
                     FMRPSPRVLVCVPVGATQVERRAIRESAQGAGAREVFLIEEPMAAAIGAGLPVSEATG
                     SMVVDIGGGTTEVAVISLNGVVYSSSVRIGGDRFDEAIINYVRRNYGSLIGEATAERI
                     KHEIGSAYPGDEVREIEVRGRNLAEGVPRGFTLNSNEILEALQEPLTGIVSAVMVALE
                     QCPPELASDISERGMVLTGGGALLRNLDRLLMEETGIPVVVAEDPLTCVARGGGKALE
                     MIDMHGGDLFSEE"
     gene            14664..15767
                     /gene="mreC"
                     /locus_tag="IRB70_002209"
     CDS             14664..15767
                     /gene="mreC"
                     /locus_tag="IRB70_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBC0632119.1"
                     /translation="MKPIFSRGPSLQIRLILAVLVALGIIIADSRLGTFSQIRTYMDT
                     AVSPFYFVSNAPRELLDGVSQTLASRDQLELENRALRQELLLKNSELLMLGQYKQENA
                     RLRELLGSPLRQDEQKMVTQVISTVNDPYSDQVVIDKGSVNGVYEGQPVISDKGVVGQ
                     VVAVAKLTSRVLLICDATHALPIQVLRNDIRVIAAGNGCTDDLQLEHLPANTDIRVGD
                     VLVTSGLGGRFPEGYPVAVVSSVKLDTQRAYTVIQARPTAGLQRLRYLLLLWGADRNG
                     ANPMTPEEVHRVANERLMQMMPQVLPSPDAMGPKLPEPATGIAQPTPQQPATGNAATA
                     PAAPTQPAANRSPQRATPPQSGAQPPARAPGGQ"
     gene            15767..16255
                     /gene="mreD"
                     /locus_tag="IRB70_002210"
     CDS             15767..16255
                     /gene="mreD"
                     /locus_tag="IRB70_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001487551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBC0632120.1"
                     /translation="MASYRSQGRWVIWLSFLIALLLQIMPWPDNLIVFRPNWVLLILL
                     YWILALPHRVNVGTGFVMGAILDLISGSTLGVRVLAMSIIAYLVALKYQLFRNLALWQ
                     QALVVMLLSLVVDIIVFWAEFLVINVSFRPEVFWSSVVNGVLWPWIFLLMRKVRQQFA
                     VQ"
     gene            16264..16857
                     /gene="yhdE"
                     /locus_tag="IRB70_002211"
     CDS             16264..16857
                     /gene="yhdE"
                     /locus_tag="IRB70_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphatase YhdE"
                     /protein_id="HBC0632121.1"
                     /translation="MTSLYLASGSPRRQELLAQLGVTFERIVTGIEEQRQPQESAQQY
                     VVRLAREKAQAGVAQTAQDLPVLGADTIVILNGEVLEKPRDAEHAVQMLRKLSGQTHQ
                     VMTAVALADSQHILDCLVVTDVTFRTLTDEDIAGYVASGEPLDKAGAYGIQGLGGCFV
                     RKINGSYHAVVGLPLVETYELLSNFNALREKRDKHDG"
     gene            16847..18316
                     /gene="rng"
                     /locus_tag="IRB70_002212"
     CDS             16847..18316
                     /gene="rng"
                     /locus_tag="IRB70_002212"
                     /EC_number="3.1.26.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006818051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease G"
                     /protein_id="HBC0632122.1"
                     /translation="MTAELLVNVTPSETRVAYIDGGILQEIHIEREARRGIVGNIYKG
                     RVSRVLPGMQAAFVDIGLDKAAFLHASDIMPHTECVAGEEQKQFTVRDISELVRQGQD
                     LMVQVVKDPLGTKGARLTTDITLPSRYLVFMPGASHVGVSQRIESESERERLKKVVAE
                     YCDEQGGFIIRTAAEGVGEAELASDAAYLKRVWTKVMERKKRPQTRYQLYGELALAQR
                     VLRDFADAELDRIRVDSRLTYEALLEFTSEYIPEMTSKLEHYTGRQPIFDLFDVENEI
                     QRALERKVELKSGGYLIIDQTEAMTTVDINTGAFVGHRNLDDTIFNTNIEATQAIARQ
                     LRLRNLGGIIIIDFIDMNNEDHRRRVLHSLEQALSKDRVKTSVNGFSALGLVEMTRKR
                     TRESIEHVLCNECPTCHGRGTVKTVETVCYEIMREIVRVHHAYDSDRFLVYASPAVAE
                     ALKGEESHSLAEVEIFVGKQVKVQIEPLYNQEQFDVVMM"
     gene            18384..22184
                     /gene="yhdP"
                     /locus_tag="IRB70_002213"
     CDS             18384..22184
                     /gene="yhdP"
                     /locus_tag="IRB70_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312145.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA2 domain-containing protein YhdP"
                     /protein_id="HBC0632123.1"
                     /translation="MRRLPGILLLTGAALVVIAALLVSGLRIALPHLDAWRPEILNKI
                     ESATGMPVEASQLSASWQNFGPTLEAHDIRAELKDGGEFSVKRVTLALDVWQSLLHMR
                     WQFRDLTFWQLRFRTNTPITSGGGNDSLEASHISDLFLRQFDHFDLRDSEVSFLTPSS
                     QRAELAIPQLTWLNDPRRHRAEGLVSLSSLTGQHGVMQVRMDLRDDEGLLSNGRVWLQ
                     ADDIDLKPWLGKWMQDNIALETAQFSLEGWMTIDKGDVTGGDVWLKQGGASWLGEKET
                     HTLSVDNLTAHITRENPGWQFSIPDTRITMDGKPWPSGALTLAWIPKQDVGGKDNKRS
                     DELRIRASNLELAGLEGVRPLVAKLSPALGDVWRSTQPSGKINTLALDIPLQAADKTR
                     FQASWSDLAWKQWKLLPGAEHFSGTLSGSVENGLLTASMKQAKMPYETVFRAPLEIAD
                     GQATISWLNNDKGFQLDGRNIDVKAKAVHARGDFRYLQPANDEPWLGILAGISTDDGS
                     QAWRYFPENLMGKDLVDYLSGAIQGGEADNATLVYGGNPQLFPYKHNEGQFEVLVPLR
                     NAKFAFQPDWPALTNLDIELDFINDGLWMKTDGVNLGGVRASNLTAVIPDYSKEKLLI
                     DADIKGPGKAVGPYFDETPLKDSLGATLQELQLDGDVNARLHLDIPLNGELVTAKGEV
                     TLRNNSLFIKPLDSTLKNLSGKFSFINGDLQSEPLTASWFNQPLNVDFSTKEGAKAYQ
                     VAVNLNGNWQPAKTGVLPEAVNEALSGSVAWDGKVGIDLPYHAGATYNVELNGDLKNV
                     SSHLPSPLAKPAGEPLPVNVKVDGNLNSFELTGQAGADNHFNSRWLLGQKLTLDRAIW
                     AADSKTLPPLPEQSGVELNMPPMNGAEWLALFQKGAAESVGGAASFPQHITLRTPMLS
                     LGNQQWNNLSIVSQPTANGTQVEAQGREINATLAMRNNAPWLANIKYLYYNPSVAKTL
                     GDSTPSSPFPTTERINFRGWPDAQIRCAECWFWGQKFGRIDSDITISGDTLTLTNGLI
                     DTGFSRLTADGEWVNNPGNERTSLKGKLRGQKIDAAAEFFGVTTPIRQSSFNVDYDLH
                     WRKAPWQPDEATLNGIIHTQLGKGEITEINTGHAGQLLRLLSVDALMRKLRFDFRDTF
                     GEGFYFDSIRSTAWIKDGVMHTDDTLVDGLEADIAMKGSVNLVRRDLNMEAVVAPEIS
                     ATVGVAAAFAVNPIVGAAVFAASKVLGPLWSKVSILRYHISGPLDDPQINEVLRQPRK
                     EKAQ"
     gene            22340..23785
                     /gene="tldD"
                     /locus_tag="IRB70_002214"
     CDS             22340..23785
                     /gene="tldD"
                     /locus_tag="IRB70_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease TldD"
                     /protein_id="HBC0632124.1"
                     /translation="MSLNLVSEQLLAANGLKHQDLFAILGQLAERRLDYGDLYFQSSY
                     HESWVLEDRIIKDGSYNIDQGVGVRAISGEKTGFAYADQISLLALEQSAQAARTIVRD
                     SGDGKVQTLGAVEHSPLYTSVDPLQSMSREDKLDILRRVDKVAREADKRVQEVTASLS
                     GVYELILVAATDGTLAADVRPLVRLSVSVLVEEDGKRERGASGGGGRFGYEFFLADLD
                     GEVRADAWAKEAVRMALVNLSAVAAPAGTMPVVLGAGWPGVLLHEAVGHGLEGDFNRR
                     GTSVFSGQVGELVASELCTVVDDGTMVDRRGSVAIDDEGTPGQYNVLIENGILKGYMQ
                     DKLNARLMGMTPTGNGRRESYAHLPMPRMTNTYMLPGKSTPQEIIESVEYGIYAPNFG
                     GGQVDITSGKFVFSTSEAYLIENGKVTKPVKGATLIGSGIETMQQISMVGNDLKLDNG
                     VGVCGKEGQSLPVGVGQPTLKVDNLTVGGTA"
     gene            complement(23913..24842)
                     /gene="aaeR"
                     /locus_tag="IRB70_002215"
     CDS             complement(23913..24842)
                     /gene="aaeR"
                     /locus_tag="IRB70_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AaeR"
                     /protein_id="HBC0632125.1"
                     /translation="MERLKRMSVFAKVVEFGSFTAAARQLQMSVSSISQTVSKLEDEL
                     QVKLLNRSTRSIGLTEAGRIYYQGCRRMLHEVQDVHEQLYAFNNTPIGTLRIGCSSTM
                     AQNVLAGLTAKMLKEYPGLSVNLVTGIPAPDLIADGLDVVIRVGALQDSSLFSRRLGA
                     MPMVVCAAKSYLTQYGIPEKPADLSSHSWLEYSVRPDNEFELIAPEGISTRLIPQGRF
                     VTNDPMTLVRWLTAGAGIAYVPLMWVINEINRGELEILLPRYQSDPRPVYALYTEKDK
                     LPLKVQVVINSLTDYFVEVGKLFQEMHGRGKEK"
     gene            25025..25228
                     /locus_tag="IRB70_002216"
     CDS             25025..25228
                     /locus_tag="IRB70_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000051842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AaeX family protein"
                     /protein_id="HBC0632126.1"
                     /translation="MSLFPVIVVFGLSFPPIFFELLLSLAIFWLVRRVLVPTGIYDFV
                     WHPALFNTALYCCLFYLISRLFV"
     gene            25236..26168
                     /gene="aaeA"
                     /locus_tag="IRB70_002217"
     CDS             25236..26168
                     /gene="aaeA"
                     /locus_tag="IRB70_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeA"
                     /protein_id="HBC0632127.1"
                     /translation="MKTLIRKFSRTAITVVLVILAFIAIFNAWVYYTESPWTRDARFS
                     ADVVAIAPDVSGLITQVNVHDNQLVKKGQVLFIIDQPRYQKALEEAQADVAYYQVLAQ
                     EKRQEAGRRNRLGVQAMSREEIDQANNVLQTVLHQLAKAQATRDLAKLDLERTVIRAP
                     ADGWVTNLNVYTGEFITRGSTAVALVKQNSFYVLAYMEETKLEGVRPGYRAEITPLGS
                     NKVLKGTVDSVAAGVTNASSTRDDKGMATIDSNLEWVRLAQRVPVRIRLDNQQENIWP
                     AGTTATVVVTGKQDRDESQDSFFRKMAHRLREFG"
     gene            26174..28141
                     /gene="aaeB"
                     /locus_tag="IRB70_002218"
     CDS             26174..28141
                     /gene="aaeB"
                     /locus_tag="IRB70_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="p-hydroxybenzoic acid efflux pump subunit AaeB"
                     /protein_id="HBC0632128.1"
                     /translation="MGIFSIANQHIRFAVKLATAIVLALFVGFHFQLETPRWAVLTAA
                     IVAAGPAFAAGGEPYSGAIRYRGFLRIIGTFIGCIAGLVIIIAMIRAPLLMILVCCIW
                     AGFCTWISSLVRIENSYAWGLAGYTALIIVITIQPEPLLTPQFAVERCSEIVIGIVCA
                     IMADLLFSPRSIKQEVDRELESLLVAQYQLMQLCIKHGDGEVVDKAWGDLVRRTTALQ
                     GMRSNLNMESSRWARANRRLKAINTLSLTLITQSCETYLIQNTRPELITDTFREFFDT
                     PVETAQDVHKQLKRLRRVIAWTGERETPVTIYSWVAAATRYQLLKRGVISNTKINATE
                     EEILQGEPEVKVESAERHHAMVNFWRTTLSCILGTLFWLWTGWTSGSGAMVMIAVVTS
                     LAMRLPNPRMVAIDFIYGTLAALPLGLLYFLVIIPNTQQSMLLLCISLAVLGFFLGIE
                     VQKRRLGSMGALASTINIIVLDNPMTFHFSQFLDSALGQIVGCVLAFTVILLVRDKSR
                     DRTGRVLLNQFVSAAVSAMTTNVARRKENHLPALYQQLFLLMNKFPGDLPKFRLALTM
                     IIAHQRLRDAPIPVNEDLSAFHRQMRRTADHVISARSDDKRRRYFGQLLEELEIYQEK
                     LRIWQAPPQVTEPVHRLTGMLHKYQHALTDS"
     gene            28233..28505
                     /locus_tag="IRB70_002219"
     CDS             28233..28505
                     /locus_tag="IRB70_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="barstar family protein"
                     /protein_id="HBC0632129.1"
                     /translation="MNIYTFDFDEIESQEDFYRDFSQTFGLAKDKVRDLDSLWDVLMN
                     DVLPLPLEIEFVHLGEKTRRRFGALILLFDEAEEELEGHLRFNVRH"
     gene            complement(28562..28825)
                     /gene="yhcN"
                     /locus_tag="IRB70_002220"
     CDS             complement(28562..28825)
                     /gene="yhcN"
                     /locus_tag="IRB70_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417705.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid stress response protein YhcN"
                     /protein_id="HBC0632130.1"
                     /translation="MKIKTTVAALSVLSVLSFGAFAADSIDAAQAQNREAIGTVSVSG
                     VASSPMDMREMLNKKAEEKGATAYQITEARSGDTWHATAELYK"
     gene            complement(29190..29660)
                     /gene="argR"
                     /locus_tag="IRB70_002221"
     CDS             complement(29190..29660)
                     /gene="argR"
                     /locus_tag="IRB70_002221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001257852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ArgR"
                     /protein_id="HBC0632131.1"
                     /translation="MRSSAKQEELVKAFKALLKEEKFSSQGEIVAALQEQGFDNINQS
                     KVSRMLTKFGAVRTRNAKMEMVYCLPAELGVPTTSSPLKNLVLDIDYNDAVVVIHTSP
                     GAAQLIARLLDSLGKAEGILGTIAGDDTIFTTPANGFTVKDLYEAILELFDQEL"
     gene            30095..31033
                     /gene="mdh"
                     /locus_tag="IRB70_002222"
     CDS             30095..31033
                     /gene="mdh"
                     /locus_tag="IRB70_002222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000861594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HBC0632132.1"
                     /translation="MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAV
                     DLSHIPTAVKIKGFSGEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLV
                     QQVAKTCPKACIGIITNPVNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIIRSNTFVAE
                     LKGKQPGEVEVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKA
                     GGGSATLSMGQAAARFGLSLVRALQGEQGVVECAYVEGDGQYARFFSQPLLLGKNGVE
                     ERKSIGTLSAFEKNALEGMLDTLKKDIALGEEFVNK"
     gene            complement(31096..32163)
                     /gene="degS"
                     /locus_tag="IRB70_002223"
     CDS             complement(31096..32163)
                     /gene="degS"
                     /locus_tag="IRB70_002223"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane-stress sensor serine
                     endopeptidase DegS"
                     /protein_id="HBC0632133.1"
                     /translation="MFVKLLRSVAIGLIVGAILLVAMPSLRSLNPLSTPQFDSTDETP
                     ASYNLAVRRAAPAVVNVYNRGLNTNSHNQLEIRTLGSGVIMDQRGYIITNKHVINDAD
                     QIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIGDVVLAIGN
                     PYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGELMGINTL
                     SFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQGGGI
                     DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMDQVAEIRPGSVIPVV
                     VMRDDKQLTLQVTIQEYPATN"
     gene            complement(32253..33620)
                     /gene="degQ"
                     /locus_tag="IRB70_002224"
     CDS             complement(32253..33620)
                     /gene="degQ"
                     /locus_tag="IRB70_002224"
                     /EC_number="3.4.21.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine endoprotease DegQ"
                     /protein_id="HBC0632134.1"
                     /translation="MKKQTQLLSALALSVGLTLSASFQAVASIPGQVADQAPLPSLAP
                     MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKG
                     YVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSD
                     KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGAL
                     LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEM
                     SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT
                     TEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGI
                     KIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESI
                     YLLMR"
     gene            complement(33774..34172)
                     /locus_tag="IRB70_002225"
     CDS             complement(33774..34172)
                     /locus_tag="IRB70_002225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1043 family protein"
                     /protein_id="HBC0632135.1"
                     /translation="MTWEYALIGLVVGIIIGAVAMRFGNRKLRQQQALQYELEKNKAE
                     LDEYREELVSHFARSAELLDTMAHDYRQLYQHMAKSSSSLLPELSAEANPFRNRLAES
                     EASNDQAPVQMPRDYSEGASGLLRTGAKRD"
     gene            34366..35493
                     /gene="zapE"
                     /locus_tag="IRB70_002226"
     CDS             34366..35493
                     /gene="zapE"
                     /locus_tag="IRB70_002226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapE"
                     /protein_id="HBC0632136.1"
                     /translation="MQSITPTSQYLKALNEGSHQPDDVQKEAVSRLEIIYQELINSTP
                     PAPRTSGLMARVGKLWGKREDTKHTPVRGLYMWGGVGRGKTWLMDLFYQSLPGERKQR
                     LHFHRFMLRVHEELTALQGQTDPLEIIADRFKAETDVLCFDEFFVSDITDAMLLGGLM
                     KALFARGITLVATSNIPPDELYRNGLQRARFLPAIDAIKQHCDVMNVDAGVDYRLRTL
                     TQAHLWLSPLNDETRAQMDKLWLALAGAKRENSPTLEINHRPLATMGVENQTLAVSFT
                     TLCVDARSQHDYIALSRLFHTVMLFDVPVMTRLMESEARRFIALVDEFYERHVKLVVS
                     AEVPLYDIYQGERLKFEFQRCLSRLQEMQSEEYLKREHLAG"
     gene            35712..36140
                     /gene="rplM"
                     /locus_tag="IRB70_002227"
     CDS             35712..36140
                     /gene="rplM"
                     /locus_tag="IRB70_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010847760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBC0632137.1"
                     /translation="MKTFTAKPETVKRDWYVVDATGKTLGRLATELARRLRGKHKAEY
                     TPHVDTGDYIIVLNADKVAVTGNKRTDKVYYHHTGHIGGIKQATFEEMIARRPERVIE
                     IAVKGMLPKGPLGRAMFRKLKVYAGNEHNHAAQQPQVLDI"
     gene            36156..36548
                     /gene="rpsI"
                     /locus_tag="IRB70_002228"
     CDS             36156..36548
                     /gene="rpsI"
                     /locus_tag="IRB70_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBC0632138.1"
                     /translation="MAENQYYGTGRRKSSAARVFIKPGNGKIVINQRSLEQYFGRETA
                     RMVVRQPLELVDMVEKLDLYITVKGGGISGQAGAIRHGITRALMEYDESLRSELRKAG
                     FVTRDARQVERKKVGLRKARRRPQFSKR"
     gene            36942..37580
                     /gene="sspA"
                     /locus_tag="IRB70_002229"
     CDS             36942..37580
                     /gene="sspA"
                     /locus_tag="IRB70_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stringent starvation protein A"
                     /protein_id="HBC0632139.1"
                     /translation="MAVAANKRSVMTLFSGPTDIYSHQVRIVLAEKGVSFEIEHVEKD
                     NPPQDLIDLNPNQSVPTLVDRELTLWESRIIMEYLDERFPHPPLMPVYPVARGESRLY
                     MHRIEKDWYTLMNTIINGSASEADAARKQLREELLAIAPVFGQKPYFLSDEFSLVDCY
                     LAPLLWRLPQLGIEFSGPGAKELKGYMTRVFERDSFLASLTEAEREMRLGRS"
     gene            37586..38083
                     /gene="sspB"
                     /locus_tag="IRB70_002230"
     CDS             37586..38083
                     /gene="sspB"
                     /locus_tag="IRB70_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClpXP protease specificity-enhancing factor"
                     /protein_id="HBC0632140.1"
                     /translation="MDLSQLTPRRPYLLRAFYEWLLDNQLTPHLVVDVTLPGVQVPME
                     YARDGQIVLNIAPRAVGNLELANDEVRFNARFGGIPRQVSVPLAAVLAIYARENGAGT
                     MFEPEAAYDEDASIMNDEEASADNETVMSVIDGDKPDHDDDTHPDDEPPQPPRGGRPA
                     LRVVK"
     gene            complement(38127..39494)
                     /gene="dcuC"
                     /locus_tag="IRB70_002231"
     CDS             complement(38127..39494)
                     /gene="dcuC"
                     /locus_tag="IRB70_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuC"
                     /protein_id="HBC0632141.1"
                     /translation="MFGIIISVIVLITMGYLILKNYKPQVVLAAAGIFLMMCGVWLGF
                     GGVLDPAKSSGYLIVDIYNEILRMLSNRIAGLGLSIMAVGGYARYMERIGASRAMVSL
                     LSRPLKLIRSPYIILSATYVIGQIMAQFITSASGLGMLLMVTLFPTLVSLGVSRLSAV
                     AVIATTMSIEWGILETNSIFAAQVAGMKIATYFFHYQLPVASCVIISVAISHFFVQRA
                     FDKKDKNINHEQAEQKALDNVPPLYYAILPVMPLILMLGSLFLAHVGLMQSELHLVVV
                     MLLSLTVTMFVEFFRKHNLRETMDDVQAFFDGMGTQFANVVTLVVAGEIFAKGLTTIG
                     TVDAVIRGAEHSGLGGIGVMIIMALVIAICAIVMGSGNAPFMSFASLIPNIAAGLHVP
                     AVVMIMPMHFATTLARAVSPITAVVVVTSGIAGVSPFAVVKRTAIPMAVGFVVNMIAT
                     ITLFY"
BASE COUNT         9728 a         9535 c        10439 g         9909 t
ORIGIN      
        1 ttcacttgca aagtaaaaaa caaattaagt tattttttgt aagttatttt gatgatattc
       61 gacatgcatc acgctttttg ccgcttttgc tgtgctagtt tgctttcaaa atgaaagtga
      121 agattctctt tcttcatttt gtaaggcgaa cgacaaataa caggagcagc gatgtacatc
      181 atttcaagca aaaacatgct gaaaaaagcc cagtcagagg gatatgccgt ccctgctttc
      241 aacattcata accttgaaac tttacaggta gtcgttgaga gcgctgcaca acttcgctct
      301 cccgttatgc tggcgggaac accgggtact tatcgttatg gcggcgtggg aagtttgatt
      361 tcgttagtac aatcgctggc tcgtgagtac aacctaccgt tagtcctgca tctcgatcat
      421 catgaagagt gtgatgacat ttttaacaag gtccgcgcag ggatccgttc tgtcatgatt
      481 gatggttccc atttgccatt tgaagacaac attgcgcgag tgcaagaagt taccgccttt
      541 tgccatcgct ttgatgttag cgttgaggcc gagctagggc gtcttggcgg tcaggaggac
      601 gatctgctgg tggatgaaaa agattcagct tatacctcac cagccgcagc tgcagagttt
      661 gttcaacgta cccaaattga ctctctggcg gtagcaatag gcactgcaca tggtttatat
      721 gcgcatgaac cacgtctgga ttttgtgcgg ctggaacaaa ttcgccagct ggtagaaatt
      781 ccgctggtgt tgcatggagc ttcaggccta tcggaacagg acgttcagct ctgtattcgc
      841 cacggtattt gtaaagtaaa tgtcgcgaca gaattgaaaa ttgcgtttgc cgatgcgtta
      901 aaaggatatt tctacaacaa tcctgcggca aatgatcctc gccactatat gcagcccgca
      961 aaggccgcca tgaaagaagt cgtaactcgt attattggcg tctgtggtag tgaaggaaaa
     1021 atttaatacg ttgtacccta caaaaacaat gaggattgtt tatgaaaaat attaaattac
     1081 ttggttcagc tatgttggtg agcctggcat tattctcgca aagttcattg gcaaaagagt
     1141 ataaaattgg tgcgtcatta ttaacacagc aacatccttt ctatattgat cttgcgaatg
     1201 ccatgaaaga agaggcaaaa aaagacaatg tcaatttaag tgtctctatt gccaatcagg
     1261 atttaaacaa acaactttct gatgttgagg attttattac taaaaaagtg gatgccatta
     1321 ttatctctcc ggttgattcg aaaggcgtcc aggcggcgat aattaaagcc gataaggccg
     1381 gtattccagt tatcaccgtt gacgtcgctg cggaaggcgt tccggtcgta tcgcacgttg
     1441 cgaccgataa ctatgcggga ggcgttgaag caggcaagtt aatgggcaag cttttgaatg
     1501 gtaaaggtac tgtagccatt atttcttatc cggcactaca atcggtggtt gcgcgcgttg
     1561 atggttttaa gaaagggtta agcgagacac cggatattaa aattgttgct gaacagccag
     1621 gtataacgcg ggctgaagcg ttaacgactg cgcaaaacat tatgcaggcc aacgccaacc
     1681 tgaatggtct gtttggcttt ggtgatgatg cggcgttggc agcggttatc gcagcgaaat
     1741 ctgcgcataa cgacaacatc aaaatcattg gttttgacgg catgaaagaa gcgcgtgatg
     1801 ccgttgacag tgaaaaaacg tttgcggccg tgattcggca atatcccgat caaatgggtg
     1861 ctaaagccat tgatgccgct gttgatcacc tcaatggtaa accggtagaa aaaatgatcc
     1921 cggtacaacc cggcgtttat acaggtaaat aataaacatc ttcatttcac aacaaaacgt
     1981 tatcgacgtt ttgttgtgac accgaggtca ttatgacgga tgttattctt gatgtttcgc
     2041 atattgcgaa gacatttggt catgttcagg cattaaaaaa tattacactc tctttacgta
     2101 aagggcgggt gcatacttta ttaggcgaga atggtgccgg taaatcgaca ttaatgaaaa
     2161 tactcgccgg tgtttatccg ccaacccagg gaacgataac actacgtggt gaaaccatca
     2221 ccattaataa tccgcagcat tctcgccagt tagggattgc gattattttt caggaactga
     2281 gcctgagtaa taatatgacc gtggcggaaa atatttatgc caataatgaa ccgcgacgtt
     2341 ttggcattat taacgataaa aaaatgctcg cagattgcca gaatctcctc gcggaactgg
     2401 gcatcccact ggatccgctg gaaatggtcg gcaatatgtc gatggcacat aggcaactgg
     2461 tagaaattgc caaagcctta agttatgcag cagatgtcgt gattatggat gaaccgacat
     2521 cttcgctaag tgataatgaa gcagagattc tgtttaacat tattgagaaa ttaaagcagc
     2581 gaggttgtgc ggttatttat atctctcatc gcatggatga aattatgcgg atttcagatg
     2641 atatttcggt gatccgcgac ggtgagtata tcgctacgca tgaaaagaaa aacagtgata
     2701 tccagcattt gattgcccaa atggttggtc gggaaatgaa aaatatttgg ccagcacgtc
     2761 ttggggaaaa gccggatgaa aatgttcctg caaaactgga agtaaaaaaa ctttcccatc
     2821 cttcgctttt taaagaggtc agtttcgctg tgcgtccggg ggaggtcctc ggattttttg
     2881 gcctggtggg ggccgggcgt tccgatgtga tgaaggcgct atttggcctc gtttcgtatc
     2941 acgggactgt gttgattgat ggtaaggaag tcaggatcgc taatcccaaa caggctattg
     3001 atcatggcat tgcttttgtg accgaaaacc gcaaggaaga agggttagtg ctgatgcacg
     3061 acgtcaatat gaacacgcac catgtggcgt ttcaatataa cgcttcgcgg atgggactca
     3121 tcaatcaccg acaagaagag gcgaagacgc tgcaatctat tgccagaatg aacactaaag
     3181 tgagttctgt acatcaggca gtgggagcgc tgagcggcgg taatcaacag aaaatcgtgt
     3241 tatccaagtg gctggagaaa actccgcgta ttttattgct cgatgagcca acgcgcggag
     3301 tggatgtcgg cgcaaaattt gaaatctata acgtgatacg tcaactgact gcggcaggga
     3361 cagcaattat tctggtgtcc tctgaactgc cagaagtcat ggcacttagc gatcgtctgg
     3421 tggtaatgcg taataaaacg attgccgata tttattcatg tgaaaattta acgcagacac
     3481 aggtaatgac cgctgcaaca ggagtacgtt aaatgacaga gaaaactctt gccagtccga
     3541 aaccttcgga aattcccatt gcaaataatt ttaaaaaagt cttcaggcaa tatggcggta
     3601 tcctcagtgg aatggtggtg ttaatcattc tgttcagttt tattaatgac agttttttta
     3661 ccgccaataa cattactaat attattcttc aggtttcgat aattgcaatt accgcctatg
     3721 gaatgactta cgtacttttg cttggcgata ttgatttatc ggttggttca accattgcat
     3781 tgattggcac atttgctgcg cttggggctt catggggaat tccatttatt ttattggtcc
     3841 cattatccat tattgcagca ctggctctgg ggatgataaa tggtggcttg acggccatag
     3901 cggggatccc gtcgtttatt gtcaccgttg ctacaatggg gatcttccgt ggtatcgctt
     3961 atatagtgac cgatggtatg cccatcatga ttaaagatga tgcctttctg gcgctgggga
     4021 atggagaatt tctctatata cctattccta tctggatatt aatcatctta ttgctgatta
     4081 accacttcat tcttactaaa acaacctttg gacgaaaaat ttatatcact ggtggtaata
     4141 aagaagcggc agtttattca gggataaatg tcacccgctt gaaaattaaa gtctttatga
     4201 ttacagccgt gctggcaggt atcagcggga tgatcctcgc ctcacgcctc tattccgggc
     4261 aaccgaattc cgcgttgagc tacgaactgg atgctattgc tgcggctgta ctgggaggca
     4321 ccagcctgaa cggcggctat ggaaccgtgg tggggacggt gatcggcgca ttaaccatcg
     4381 gcgttattaa taatggcatg aacttaatga atgttcccta tttttaccag atggtggtta
     4441 aaggattagt cattcttgta gccgtttatt ttgacgtaag aaataaaaga aaacgcagct
     4501 aatcatttca aggaattaat catatgagta aggtcttcac aattggagaa attctggttg
     4561 aaattatggc gagtaaaatc ggccagccat ttgatcaacc aggtatctgg aacggccctt
     4621 atcccagtgg cgcgcccgct atttttatcg accaggtgac acgtcttggc gttccgtgcg
     4681 gcatcattag ctgtgtgggg aatgatggct ttggtgatat taatatacat cgtctggctg
     4741 ctgacggtgt ggatatcagg gggatttcag tcttacctct ggaagctacc gggagtgcct
     4801 ttgttactta tcataactct ggcgatcgcg attttatttt taatatcaag aatgccgctt
     4861 gcggtaaatt atcggcgcag catgttgatg aaaatattct gaaggactgt acccattttc
     4921 atattatggg ttcatccctg ttttcattcc atatggtaga cgcagtaaag aaagcggtaa
     4981 ccattgtaaa agagaatggt ggcgttattt cttttgaccc taatattcgg aaagagatgc
     5041 tcgatattcc agaaatgcgt gacgccctcc actttgttct tgagttaaca gatatctata
     5101 tgcccagcga gggagaagtg ttgctcttgt cgccacactc gacaccggag cgtgcaatcg
     5161 ctggttttct tgaagaaggt gttaaagagg tgattgtgaa gcgcggcaat caaggtgcca
     5221 gttactactc cgcgaatgag cagtttcatg ttgagagcta tccggtggaa gaagttgacc
     5281 cgaccggtgc gggagactgc tttggtggcg cgtggattgc ctgccgccag ctagggtttg
     5341 acgcccatcg ggcattacaa tatgccaacg cctgcggtgc actggcggta acccgacgtg
     5401 gcccaatgga gggaacgtct cgccttgcgg aaatcgaagc gttcatccag cgccatgaca
     5461 tgtccattcg ggaagcagca caatgaaaaa cgaaatttgg tcgtggattg gcgatctctc
     5521 gcaggttgcc ggaattaaac actatgagtt acgtagtggc agagcaaagg ggacagaagc
     5581 gtttgatgtc cgtactggtg cgggactggc atttacggtg gtaaaagatc gagcgctgga
     5641 tattgcatgg gccagctaca aggacactgc gctctctttt atcaccccca acggcattgt
     5701 cgcccccgct ttttttgagt ctcagggcaa cgggttttta cgtagcttct acgcggggtt
     5761 actgactacc tgcggactta gctacattgg cacgccctgt gaggataacg gagaaacgct
     5821 ggggttacat gggcgtttgg ctgcgactcc agcagaagag gtggggtatc gcacagaacg
     5881 gaccgacgac ggcattgaat ttgtcatcaa tggcaaagta cgggaaacac gattgttcgg
     5941 tgaaaatctg acgctggaaa ggaccattcg ctgccgttat ggcgaaaatg tgctgcgcat
     6001 tgaagacaag gtgactaatc atggtttcac ccgccagccg ctgcaaattc tttatcactt
     6061 taattacggc tggcctttat tatcgccaca ggcagaaatc ttgctgtcgg ctaaaagcgt
     6121 aacgccacga accccgcatg cggcggaagg gttaaccagt catctggaga tttgtacccc
     6181 acagcccggt tttgacgagc aggtttacta tctcacgttg aatagcgaca gtcaggggat
     6241 gagtaaagtt gcgctggtga acgccgaact ggggtgggga atttacgaga aattcgacac
     6301 catgcagcta cccaacttta tccagtggaa aaatttaggc gcgggtgaat atgttatggg
     6361 gctggaggtc agcaatagtt ttcctgacgg tcgtgataaa gaacgagcgc aggggcgtct
     6421 gccctttata gagccagggg aaacaaagac atactgcttt gagctgggaa ttgttgatgg
     6481 cgatgctgaa attagcgcgt tgaaagcgga aattgcaagc taccgttagc taacggcaat
     6541 aaaaacgccg ggcagcgtta acaggcccgg cgttgattac gttctttgct aagcgcgatg
     6601 aaaacaccgc gcgtcacaaa ttatttttcc tgaagaccga gttttttctc cagatagtgg
     6661 atgttagtgc caccatgctg gaagttctcg tcattcatga tgcggatctg cagatcaacg
     6721 ttggttttga taccgtcgat gatcagttcc tgcagcgcat tcttcatgcg ggcaatcgcc
     6781 acgtcacggt tttcaccgta gcaaatcagc ttaccgatca ttgagtcata gtacggcggt
     6841 acggtgtagc ccgcgtagat atgagactcc caacgcacgc caaaaccgcc aggtgcatgg
     6901 aaacgggtga ttttgcccgg acttggcagg aaggtgttcg gatcttcggc gttgatacgg
     6961 cactctaccg catggccgcg aacgtgaact tcttcttgct tgatcgacag cggttgaccg
     7021 gcagcgatac gcagctgttc tttgatcagg tcaacgccgg tgatcatttc agtaaccggg
     7081 tgttctacct gaatacgggt gttcatttcg atgaaataga actcgccatt ttcgaacagg
     7141 aactcgaaag tacctgcacc gcgatagccg atatcaacac atgctttagc gcaacgttcg
     7201 ccgatgtagc gacgcagttc cggggtaatg cccggtgctg gtgcttcttc gaccactttc
     7261 tggtggcggc gctgcatgga gcagtcacgt tccgccagat agatagcgtt gccctgaccg
     7321 tcagccagta cctgaatctc gacgtggcga ggattttcca ggtatttctc catgtaaacc
     7381 atatcgttgc tgaaagcagc tttcgcttcc gcacgggtca tggagatgga ttgtgccagt
     7441 tcagcgtcgc cgcgcactac gcgcataccg cgaccgccgc cgccgccgga ggctttgata
     7501 attaccggat aaccaatgcg tttagcaatg gcgcggtttt tatccatatc gtcgcccagc
     7561 gggccgtcag aacccggtac gcaaggaacg cccgcttttt tcatcgccgc gattgcggat
     7621 actttgtcgc ccatcaggcg aatggtttct gctttcgggc caatgaagat aaagccggag
     7681 cgctcaacct gctcggcaaa gttggcgttc tcggagagga agccgtagcc cggatggatt
     7741 gctactgcgc cggtgatttc agcggcgctg atgattgccg ggatgttcag ataacttttt
     7801 actgacggag cagggccgat acagaccgtt tcatctgcca gtaatacgtg ttttagatcg
     7861 cgatccgcgc tggagtgcac agcgacagtc ttgatgccca gttctttaca ggcacgaaga
     7921 atacgcaatg caatctcgcc gcggttggca ataacaattt tatccagcat gttcgcctcg
     7981 ttactcgatg acgaccagcg gctcgtcaaa ttctaccggt tgtccacttt cgaccagaat
     8041 tgctttcaca gtaccggatt tgtctgcttc gatctggttc atcattttca tggcttcaac
     8101 gatgcacagg gtatcgccca cgttgacttt ctgacccact tcgatgaacg cttttgcgtc
     8161 cgggcttggg gtgcggtaga aagtaccaac catcggggaa cgtacgatgt gaccactgat
     8221 ttccgctgct gctggcgctt ccattgaagg aacggtcgcc ggagcggctg cgttagattg
     8281 agctggctgc tgcatcattg gtgcagcgta agcttgttgc atcacaggga aacttgcggc
     8341 aggagctgca cggctaatgc gtactgactc ttcgccttca gaaatttcca gttcggagat
     8401 gcctgattct tcaaccagct cgatcagttt tttaatctta cgaatatcca tgagtgggtt
     8461 ccgtactctt tgtttagtgt gattgtgaca ggcgtttcac cgccgtctgt aaagcgtatg
     8521 ccccgacagc tgtatgcata gcgataaatt ccagcaggcc gggacgccgg tctattttgc
     8581 cccagagtgt caatgttaga cttgacggac attgtgcagc gatctgctgc tatcctccgg
     8641 caaaaaacaa aatatacctt cgttgcgcca atgtcacctt ttccgcagcg caaaaactgc
     8701 gtcagggagg acgaggtcgc acattataac gatttcgtag caattggcag ctaaatactg
     8761 gtcttatcag ggaagataat caacagctaa catgtaaata accttcaaca ccgtgtaatt
     8821 tgcaacaagc cgcacaattc acgaaattag cgccatcatc gacggaactt cttataacgt
     8881 aaggtgaaaa gctgtaaagc cagccctgcg aagatgaggg gctgcaatga gataatcttc
     8941 acagaccaca aataatgtag ggatgccagg atcgcgacaa gatagacgac attacgcagc
     9001 ggttgctggg gattgcccaa ttttcactgc atcgtctgga tagatgtgaa tgctaaagca
     9061 cgcaaaatca accgactgat aatgctcagt atgaaatagg tttaagtggt taatttgtaa
     9121 tcaaataaaa tcagattatt ccccccattt tgcagaaggt aaactgtttt gtcaggcggc
     9181 agtgcggcta tgtgatgcat tcagaatttg ccgcgtgaca ataaaaaagc cgatttggtg
     9241 gcaaaatcgg cttcggtgag tttgcagcat tcatcacata ctccgacaag ctttttcaag
     9301 catgacggag gttgcgttaa tgcaaggttt ctacccaggg ataaaagtga ccgttacggc
     9361 ggatgaatat ctgtgttgtc agaggatggt catcctcacg gaagcattgt tctgttaact
     9421 gtcgtaatgc gctgagattt gctggctgat cattgtaggt gaaaaacagt tttcctctgg
     9481 agggaacagt cactaacagg tcgccgcatt caggatcggg tgattgcacc caaagatcgt
     9541 caatgagcat cagactgggc tcataagtac cccctgcgga gataacggca acttttccag
     9601 cgtttgcgcc tgtatcaacg atttcagccg aaacttccgg caatatttgc ttcaaattat
     9661 tgatggcttg ttcgcggtca atggtcactt cgtagcgcat cagatagcgc atggtttcgc
     9721 taccatcttc agcaaacaag ataattaact catcgttaaa gtcttcccag gcaaaatcca
     9781 gcgaggcgtt gaggatctct ggatcagatt catactggct aagctgttgg cgaacggtat
     9841 ccagccaggc tttttcttta atcaccggaa caatacagcg cccggtcggc agcatttctg
     9901 caagctgttt cagcatatct gcagccactt cttccagcgg gtctggtgcg gcttgataac
     9961 gtttgtaggc atcatcaaga gtgatttcca ccgtttggtg acccgtatca atgcgcatca
    10021 atttatggtc agtcgaaatc atgactttcc agtttggatg atgttgtaca acttcatgac
    10081 caagatgttc gacgaaagct gtccggctaa ccgcttttcc cgttaaccga ttgaataatg
    10141 atttcaaaat gagttccctc tcttattaat ccttgctaaa tggttagtta accttcacca
    10201 gcgtgcgacc ctggatctgg ttattaatga tggcctcggc aaacttcggt gcatctgcca
    10261 gagatatctc ttttgccgcc tgggtataga atgattccgg taaatcggcg accagtcgct
    10321 gccaggcttg tgcgcggcgt gctggtggcg tcatcactga atctaccccc tgtaaacgga
    10381 cattacgcag aataaatggc atgaccgtgg ttggcagagt aaaaccaccc gccagaccac
    10441 aggccgccac gcagccgccg taattcattt gcgccagcac ttttgccagc actttgtcgc
    10501 caacggtgtc aattgcccct gcccagactt gtttttccag aggacgggat tcggcaaact
    10561 catcgcgagg gagaatacgg ctggcaccta aacttttcag atattcatgg gtactttcgc
    10621 gaccggaaac ggcaacgacc tgataaccca acttatgcag cagcgccacg gcggtactgc
    10681 cgacgccacc actggcaccc gtcacgacaa tctccccatc ctgcgggcga acaccggcat
    10741 cttccagcgc catcacacac agcatggcgg taaaaccggc agtaccgata atcattgctt
    10801 tacgcgcgtc cagcccttgt ggcatggcaa ccagccagtc acctttcact cgcgcctgtt
    10861 ccgccagccc accccagtgg ttttcaccaa cgccccagcc agtgagtaat acgtcctgac
    10921 cggcatgaaa acgcggatct tcgctggtgc gtacagttcc ggcaaaatcg atcccaggaa
    10981 tcatcggaaa attacggatg atttttccct taccggtaat tgccagcgca tctttgtagt
    11041 tcaggctcga ccagtgaaca tcaaccgtga catcgccctc cggcaggcga ctttcgtcca
    11101 gtgtctgtac cgatacgaga gttttgccgt cctgctgttc taaaagtaac gcctgcataa
    11161 gtggtcctca tgtgcatgat ggattggaaa ataatttctg aagactatac tcgctaatgg
    11221 aaaagcaaag ccgatgaagc gcaataaatt gcgagataaa tctgatttgc tagtatgccc
    11281 gcttcctcac tatcggagtt aacacaagga tgagattaac gacgaaattt tcggcctttg
    11341 ttacgctgct caccgggtta acaatttttg tgactttgtt gggctgttcg ctaagtttct
    11401 acaacgccat tcagtataag tttagtcatc gtgttcaggc ggtggcgacg gcgattgata
    11461 cccatcttgt gtcgaatgac ttcagcgcat taaggccaca aattaccgaa ttaatgatgt
    11521 cagcagatat cgttcgtgta gacctgctgc atggtgataa acaggtttat accctggcca
    11581 gaaatggtag ttatcgtccg gttggcacca acgatctatt tcgtgaactg agcgttccgt
    11641 tgataaagca tccggggatg tcgctgcgtc tggtttatca ggatccgatg ggcaactatt
    11701 tccattcttt aatgactacc gcgccgctca cgggggcgat tggctttatc attcttatgc
    11761 tcttcctggc ggtacgctgg ttacaacggc aacttgccgg gcaagaattg ctggaaaccc
    11821 gggctactcg tatcttaaac ggtgagcgtg gctctaatgt gttgggaacc atctatgaat
    11881 ggccgcccag aaccagcagt gcgctggata cgctgctttg tgaaattcag aacgcacgcg
    11941 aacaacacag ccgtcttgat acgctgatcc gctcttatgc cgcccaggac atgaaaaccg
    12001 gcctcaataa ccgcctcttt ttcgataatc agttagcaac gttactggaa gatcaagaga
    12061 aagtaggtac ccacgggatc gtgatgatga ttcgtctgcc ggatttcaat atgttgagtg
    12121 atacctgggg gcacagccag gttgaagaac agttcttctc tctgacgaat ctgctatcga
    12181 catttatgat gcgctaccct ggcgcactgc tggcgcgtta ccaccgcagt gattttgctg
    12241 cgctgttacc gcaccgaacg ttaaaagagg cagagagcat cgccagtcag ttaatcaaag
    12301 ccgtcgatac cttgccgaac aataaaatgc tcgatcgcga cgatatgatc cacattggta
    12361 tctgtgcctg gcgtagtggt caggataccg agcaggtaat ggaacatgca gagtctgcca
    12421 cgcgtaatgc gggattgcag ggcggcaata gctgggctat ttacgatgac tcgttgcctg
    12481 aaaaaggacg cggtaatgtt cgctggcgta cgcttatcga gcaaatgctg agtcgcggcg
    12541 gcccgcgcct ttatcaaaaa ccggcggtta ctcgcgaagg ccgggttcat catcgtgaac
    12601 tcatgtgccg catcttcgat ggtaatgaag aggttagctc ggcagagtat atgccgatgg
    12661 tcttgcagtt tggtttatcg gaagagtatg accgcctgct aatcagccgt cttattccac
    12721 tattgcgtta ctggccagag gaaaatctgg cgattcaggt taccgttgag tcgctgattc
    12781 gcccgcgttt tcagcgttgg ctgcgcgata cgttaatgca atgtgaaaaa tcgcaacgaa
    12841 gacgcataat tattgaactt gcagaggccg atgttggtca acatatcagt cgcttacaac
    12901 ctgttattcg tttagtgaat gctttagggg tacgggtagc cgtcaaccag gctggtttga
    12961 cgctggtaag caccagttgg atcaaagaac ttaatgttga gttactcaag ctccatccgg
    13021 ggctggtcag aaacattgag aagcgaacgg agaaccagct gctggttcaa agcctggtgg
    13081 aagcctgctc cgggaccagc acccaggttt acgccaccgg cgtgcgttcg cgaagcgagt
    13141 ggcagaccct gattcagcgc ggtgttacag gtgggcaagg ggattttttc gcgtcctcac
    13201 agccacttga tactaacgtg aaaaaatatt cacaaagata ctcggtttaa cctgccgttt
    13261 aatccgtttt cacgtagaat aacgcgcgct gcgtctcatg ggagtgtgct tgtctgctcg
    13321 ccagattgtt gcagcacata tgcagatgaa tgaccttacg cggttgcaaa caggcgagga
    13381 atgctgctga tgcattaagc ctttctggac tcaggcagag atttgtaaca aaggaaacga
    13441 actgcactaa ttttcaccgt agcagatgat ttttgcgcct tgtcgctgct gcgtgtggtt
    13501 ggtaaagtaa gcggattttc ttttccgccc cagctttcag gattatccct tagtatgttg
    13561 aaaaaatttc gtggcatgtt ttccaatgac ttgtccattg acctgggtac tgcgaatacc
    13621 ctcatttatg taaaaggaca aggcatcgta ttgaatgagc cttccgtggt ggccattcgt
    13681 caggatcgtg ccggttcacc gaaaagcgta gctgcagtag gtcatgacgc gaagcagatg
    13741 ctgggccgta cgccgggcaa tattgctgcc attcgcccaa tgaaagacgg cgttatcgcc
    13801 gacttcttcg tgactgaaaa aatgctccag cacttcatca aacaagtgca cagcaacagc
    13861 tttatgcgtc caagcccgcg cgttctggtt tgtgtgccgg ttggcgcgac ccaggttgaa
    13921 cgccgcgcaa ttcgtgaatc cgcgcagggc gctggtgccc gtgaagtctt cctgattgaa
    13981 gaaccgatgg ctgccgcaat tggtgctggc ctgccggttt ctgaagcgac cggttctatg
    14041 gtggttgata tcggtggtgg taccactgaa gttgctgtta tctccttgaa cggcgtggtt
    14101 tactcctctt ccgtgcgcat tggtggtgac cgtttcgacg aagctatcat caactatgtg
    14161 cgtcgtaatt acggttctct gatcggtgaa gccaccgcag aacgtatcaa gcacgaaatc
    14221 ggttcggctt acccgggcga tgaagtccgt gaaatcgaag ttcgtggccg taacctggca
    14281 gaaggtgttc cacgcggttt taccctgaac tccaacgaaa tcctcgaagc actgcaggaa
    14341 ccgctgaccg gtattgtgag cgcggtaatg gttgcactgg aacagtgccc gccggaactg
    14401 gcttccgaca tctccgagcg cggcatggtg ctcaccggtg gtggcgcact gctgcgtaac
    14461 cttgaccgtt tgttaatgga agaaaccggc attccagtcg ttgttgctga agacccgctg
    14521 acctgtgtgg cgcgcggtgg cggcaaagcg ctggaaatga tcgacatgca cggcggcgac
    14581 ctgttcagcg aagagtaatc ggatgcaggc aggggaagcg tctgtttacc ctgcctggtc
    14641 tgatacgaga atacgcataa cttatgaagc caatttttag ccgtggcccg tcgctacaga
    14701 ttcgccttat tctggcggtg ctggtggcgc tcggcattat tattgccgac agccgcctgg
    14761 ggacgttcag tcaaatccgt acttatatgg ataccgccgt cagtcctttc tactttgttt
    14821 ccaatgctcc tcgtgaattg ctggatggcg tatcgcagac gctggcctcg cgtgaccaac
    14881 tagaacttga aaaccgggcg ttacgtcagg aactgttgct gaaaaacagt gaactgctga
    14941 tgcttggaca atacaaacag gagaacgcgc gtctgcgcga actgctgggt tccccgctgc
    15001 gtcaggatga gcagaaaatg gtgactcagg ttatctccac ggttaacgac ccttatagcg
    15061 atcaagttgt tatcgataaa ggtagcgtta atggcgttta tgaaggccag ccggtcatca
    15121 gcgacaaagg tgttgttggt caggtggtgg ccgtcgctaa actgaccagt cgcgtgctgc
    15181 tgatttgtga tgcgacccac gcgctgccaa ttcaggtgct gcgcaacgat atccgcgtga
    15241 ttgcagccgg taacggttgt acggatgatt tgcagcttga gcatctgcca gcgaatacgg
    15301 atattcgtgt tggtgatgtg ctggtgactt ccggtctggg cggtcgtttc ccggaaggct
    15361 atccggtcgc ggttgtctct tccgtaaaac tcgataccca gcgcgcttat actgtgattc
    15421 aggcgcgtcc gactgcaggg ctgcaacgtt tgcgttatct gctgctgctg tggggcgcgg
    15481 atcgtaacgg cgctaacccg atgacgccgg aagaggtgca tcgtgttgct aatgaacgtc
    15541 tgatgcagat gatgccgcag gtattgcctt caccagacgc gatggggcca aagttacccg
    15601 aaccggcaac ggggatcgct cagccgactc cgcagcaacc ggcgacagga aatgcagcta
    15661 ctgcgcctgc tgcgccgaca cagcccgctg ctaatcgctc tccacaaagg gctacgccgc
    15721 cgcaaagtgg tgctcaaccg cctgcgcgtg cgccgggagg gcaatagtgg cgagctatcg
    15781 tagccaggga cgctgggtaa tctggctctc tttccttatt gcgcttttgc tgcaaatcat
    15841 gccctggccg gacaacctga tagttttccg gccaaactgg gtgttactca tcttgttgta
    15901 ttggatcctg gccttgcctc atcgcgtaaa tgtgggcaca ggttttgtga tgggtgccat
    15961 actggatctg atcagcggct cgacacttgg cgtacgcgta ttggcgatga gcatcattgc
    16021 ttacctggtg gcgctgaaat accagctttt ccgcaacctc gcattatggc agcaggcgct
    16081 ggtcgtcatg ttgctttcgc tggtggtgga tattattgtt ttctgggcag agtttttagt
    16141 gattaacgtc tctttcagac cggaagtgtt ctggagtagt gtagtcaatg gagtgctctg
    16201 gccgtggatt ttcttgctga tgcgtaaagt ccgtcagcag tttgcagtgc aataaaggtt
    16261 tctatgactt ctctgtattt agcttccggt tctccgcgtc gtcaggagtt acttgcgcaa
    16321 cttggcgtaa cctttgaacg tattgttacg ggcattgagg agcagcgtca gccgcaggag
    16381 agcgcgcagc aatatgttgt gcgtctggcg cgcgagaaag cacaggcggg tgtcgcgcaa
    16441 acggcgcagg atctcccggt gctgggtgcg gatactatcg ttatcctgaa tggagaagtg
    16501 ctggagaaac cgcgcgacgc agagcatgcg gtgcagatgt tgcgcaaatt atcgggtcag
    16561 acccatcagg taatgacggc agtggcgttg gccgacagcc agcacattct cgattgcctg
    16621 gtggtcaccg atgtgacttt cagaacgtta acagacgaag acatcgcggg ctatgtcgcc
    16681 agcggtgaac cgttagataa agcaggtgca tacggtattc aggggctggg tggctgtttt
    16741 gtcaggaaga taaatggcag ctatcacgcc gtagtcggct taccgctggt tgaaacgtat
    16801 gaattattaa gtaattttaa cgcactgcgt gagaaaaggg ataaacatga cggctgaatt
    16861 gttagtaaac gtaacgcctt cggaaacgcg agtggcgtat attgatggcg gtattctgca
    16921 ggaaattcat attgaacgtg aggcgcgacg cggaatagta ggcaatatct acaagggtcg
    16981 tgtaagtcgt gtacttccgg gtatgcaggc ggcttttgta gatattgggc tggataaagc
    17041 cgcgtttctt catgcatccg acatcatgcc gcacaccgaa tgtgtggcgg gtgaagaaca
    17101 aaagcaattc acggtgcgcg acatctcgga gctggtccgt caggggcaag atctgatggt
    17161 gcaggtggtg aaagatccgc ttggcactaa gggtgcgcgc ctgaccaccg atatcacgct
    17221 gccttctcgc tatctggtat ttatgccagg ggcttctcac gttggggttt cccaacgaat
    17281 tgaaagcgaa tcagaacgtg aacgcctgaa aaaagtggtc gcagagtatt gcgacgagca
    17341 gggcgggttt atcatccgta ccgcagcgga aggggttggc gaggctgaac tggcctccga
    17401 tgccgcttat ctgaaacgcg tctggaccaa agttatggag cgtaaaaagc gcccacagac
    17461 ccgttatcag ctgtacggcg aactggcgct ggcgcagcgt gttctgcgtg atttcgccga
    17521 cgccgaactc gaccgcattc gcgttgactc acgcctgact tacgaagcat tgctggagtt
    17581 tacctcggag tacattcccg agatgaccag caagctggag cattacaccg gacgccagcc
    17641 gattttcgat ctctttgatg tcgaaaacga aatccagcgg gcgctggaac gcaaagtaga
    17701 actgaaatcc ggtggctatc tgattatcga ccagaccgaa gcgatgacca ccgtggacat
    17761 caataccggg gcgtttgtcg gtcatcgcaa tctggacgac accattttca ataccaatat
    17821 tgaagcgacg caggctatcg ctcgccagtt acggttgcgt aatctgggcg ggattatcat
    17881 tattgatttc atcgatatga ataatgaaga tcaccgccgc cgcgtgctgc actcgctgga
    17941 gcaggcgttg agcaaagatc gggtgaaaac cagcgttaat ggtttttcgg cgctggggct
    18001 ggtggagatg acgcgtaaac gcacccgcga aagcattgag cacgtactgt gtaacgaatg
    18061 cccaacctgc cacggtcgcg gaacggtgaa aaccgtggaa acggtatgct atgaaatcat
    18121 gcgcgagatt gttcgtgtcc accatgctta cgactccgac cgtttcctgg tctatgcttc
    18181 tccggcagta gctgaagcct tgaaaggcga agagtcacac tcgctggcgg aagtggaaat
    18241 tttcgttggc aaacaggtta aagtacaaat tgaaccgctc tataaccagg agcagtttga
    18301 cgtcgtaatg atgtaaacag atgctgggcc gccatccggc aaagggtttt tgagtcacat
    18361 ttttagcaga caaggagtga cgggtgaggc gattgccggg gattttactg cttactggag
    18421 ctgcgctcgt tgtgatcgct gccctgctgg ttagcggcct gcgtattgct ttaccgcatc
    18481 ttgacgcctg gcgtccggaa atcctcaaca aaatagaatc cgcgactggc atgccggtag
    18541 aagccagtca gctctcagcc agctggcaga attttggtcc gacgcttgaa gcgcacgaca
    18601 tccgtgcaga actaaaagat ggcggcgaat tttcggttaa acgcgttact ctggcgctgg
    18661 atgtctggca gagcctgtta catatgcgct ggcagtttcg cgacctcact ttctggcagc
    18721 tgcgctttcg caccaacact cctatcacca gcggcggtgg taatgatagc ctggaagcca
    18781 gtcacatcag cgatctgttt cttcgtcaat ttgaccattt cgatctccgc gacagtgaag
    18841 tcagtttcct gacgccatcc agtcagcgcg ccgagctggc gatcccacag ctcacctggc
    18901 tgaacgatcc acgtcgacac cgtgcggaag gcctggtaag cctctccagc cttaccggac
    18961 agcacggcgt gatgcaggtg cgtatggatt tgcgcgatga tgaggggttg ttaagcaatg
    19021 gtcgcgtctg gctccaggcg gatgacatcg acctgaagcc gtggctcggt aaatggatgc
    19081 aggacaatat tgcgctggaa acggcacagt tctcccttga aggctggatg acgatcgaca
    19141 aaggcgatgt aaccggcggt gacgtctggc tgaaacaggg cggtgccagc tggttgggcg
    19201 agaaggaaac acatacgctg tcggtggata atctgactgc gcatattacg cgtgaaaatc
    19261 cgggatggca gttctctatt cccgatacac ggatcacgat ggacggcaaa ccctggccga
    19321 gcggagcatt gacgctggcc tggataccga aacaggacgt tggcggcaaa gacaataaac
    19381 gcagtgacga actccggatt cgcgccagta atctggagct ggcaggcctg gagggcgtac
    19441 gcccgctggt cgcgaaactt tcacctgcac tgggtgatgt ttggcgctcc acacaaccga
    19501 gcggcaagat taacactctg gcgctggata tcccgcttca ggcggcagac aagacccgtt
    19561 ttcaggcatc gtggagcgat ctggcctgga agcaatggaa attattaccg ggtgcggaac
    19621 acttctccgg gacgctttcc ggcagcgtag aaaatggttt gcttaccgcg tcgatgaagc
    19681 aggcaaagat gccttacgaa acggtattcc gtgcaccact ggaaatcgcc gacggccagg
    19741 caacgataag ctggctgaac aatgacaaag gtttccagct ggatggacgt aatattgacg
    19801 ttaaagccaa agccgtccat gcgcgcggcg attttcgtta cctgcaacct gctaacgatg
    19861 aaccctggct ggggattctg gctggcatca gtaccgatga tggttcacaa gcctggcgct
    19921 atttcccgga aaacttgatg ggtaaagacc tggttgatta cttaagtggc gcgattcagg
    19981 gcggtgaagc ggataacgcg acgctggttt atggtggcaa tccgcaactc ttcccctata
    20041 aacacaatga aggtcagttt gaagtgctgg tgccgctgcg caacgcgaag tttgccttcc
    20101 agccggactg gcctgcatta actaaccttg atattgaact ggactttatt aacgacggtt
    20161 tatggatgaa aaccgatggc gttaatctgg gcggcgtgcg tgcgagtaat ctcaccgcag
    20221 tgatccctga ctactcaaaa gaaaaactgc tgattgacgc tgacattaaa ggcccgggta
    20281 aagccgtcgg cccttacttt gatgagacac cgctgaaaga ttctctgggg gcgaccctgc
    20341 aagaactcca gctcgacggc gatgtgaatg ctcgcttaca tctcgatatt ccgctgaacg
    20401 gcgaactggt aaccgcgaaa ggtgaagtga cgctgcgtaa taacagtctg tttatcaaac
    20461 cactcgacag caccctgaaa aatttgagcg ggaaattcag ctttattaat ggcgatctgc
    20521 aaagtgaacc actgacagca agctggttta atcagccgtt gaacgtggat ttttccacca
    20581 aagaaggggc aaaagcctac caggtcgcgg tgaatctcaa cggtaactgg caaccagcga
    20641 aaaccggcgt tctgcctgaa gcggtgaacg aagcattaag tggcagcgtg gcgtgggatg
    20701 gtaaagtggg cattgatctg ccttatcatg ctggcgcgac ctataacgta gagctaaacg
    20761 gcgatttgaa gaatgtgagc agtcacttac cttcaccgtt agccaaacct gcgggtgaac
    20821 cactgccggt aaacgttaag gttgatggca atctcaacag ctttgagtta accggacagg
    20881 ctggtgcaga taaccatttc aatagccgct ggttgcttgg tcaaaagctg acgctcgacc
    20941 gtgctatttg ggcggcagac agtaaaacgc tcccgccgtt gccggaacaa agtggcgttg
    21001 aactcaatat gccgccgatg aatggtgccg agtggctggc cctgttccag aaaggcgcgg
    21061 cggagagtgt cggtggtgca gcgagtttcc cacaacacat aacgttacgt acgcctatgt
    21121 tgtcgctggg aaatcagcaa tggaataacc tgagtattgt ttcgcaaccg acggcaaatg
    21181 gcacccaggt tgaggcgcaa gggcgtgaaa tcaacgccac gctggcgatg cgtaataacg
    21241 caccgtggct ggcgaatatc aaatatcttt attacaaccc aagcgtggcg aaaactcttg
    21301 gtgattcaac gccgtcatca cctttcccga caacggaacg cattaacttc cgtggctggc
    21361 cagacgcaca aatacgatgc gcagagtgct ggttctgggg gcaaaaattc ggtcgcattg
    21421 acagtgatat caccatttct ggcgatacgt taacgctgac taatggactg attgatactg
    21481 gtttttcgcg gctcactgcc gatggtgaat gggttaacaa tccggggaat gaacgtacct
    21541 cgctgaaagg aaaactgcgc gggcagaaaa ttgatgccgc cgcagaattt tttggtgtca
    21601 cgacgcccat acgccagtcg tcatttaatg tggattacga tttacactgg cgcaaagcac
    21661 cctggcagcc agatgaggcg acgttgaatg gcatcattca tactcaactg ggtaaaggcg
    21721 aaattaccga aatcaatacc ggacatgccg ggcaattgct gcgcttattg agcgtagatg
    21781 ccctgatgcg taagctgcgt tttgatttca gagacacttt tggcgaaggg ttctattttg
    21841 actccattcg cagcaccgcg tggattaaag acggcgttat gcacaccgac gacacgctgg
    21901 tggatggcct ggaagcggac atcgctatga aagggtcggt aaatctggta cgtcgcgacc
    21961 tgaatatgga agcggttgtc gcaccagaga tttctgcgac ggtgggtgtg gctgcggcct
    22021 ttgcggttaa ccccattgtt ggcgcggcag tgtttgccgc cagtaaagtg ctgggaccgc
    22081 tgtggagcaa agtctccatt ttgcgctatc acatttcggg tccgctggac gatccgcaaa
    22141 tcaacgaagt gttgcgacaa ccgcgtaaag aaaaagcgca atgatttgac gagggcgcgt
    22201 aattgcccca atctcatagg ataatcgttg ccaaaggcca acgagccaga acataaccgt
    22261 aggccggaca gggcgttcac gccgcatccg gcagccgtaa aaaatcctct actgcagtaa
    22321 ctaacgagta gcaaaaacga tgagtctgaa cctggtaagt gaacaattgc tagcggcgaa
    22381 cggcctgaaa catcaggact tgttcgcgat cctcggtcaa ctggccgaac gtcgccttga
    22441 ttatggcgat ctctattttc agtcgagcta tcacgaatcc tgggttttag aagaccgtat
    22501 tattaaagat ggttcttaca acatcgatca gggcgttggc gtgcgtgcaa tcagtggtga
    22561 aaaaaccgga tttgcttacg ctgaccaaat cagcctgctg gcgctggaac agagtgcaca
    22621 agcggcgcgc accatcgtcc gtgatagtgg tgatggcaaa gtacagacgc tgggcgcggt
    22681 agagcatagc ccgttatata cctcggtaga tccgctgcaa agcatgagcc gtgaagataa
    22741 gctggatatc ctgcgtcgcg tcgataaggt tgcccgcgaa gcggacaagc gcgtacagga
    22801 agtgactgcc agcctcagtg gtgtctatga attaattctg gttgcggcca ccgacggcac
    22861 gctagcggcg gatgtccgtc cgctggtgcg tctttccgtg agcgttctgg tcgaagaaga
    22921 tggcaaacgc gaacgcggtg ccagtggcgg cggcggtcgt tttggttatg agttcttcct
    22981 tgccgatctc gacggcgaag tccgtgcgga tgcgtgggca aaagaagcag tgcgtatggc
    23041 gctggtcaat ctttctgccg ttgctgcacc agcgggcacc atgccggtag tacttggcgc
    23101 aggttggccg ggcgtgctgt tgcatgaagc ggtgggtcac ggtctggaag gcgacttcaa
    23161 ccgccgtggc acttcagtat ttagtggaca ggtcggggag ttggtggctt cagaactgtg
    23221 taccgtggtt gatgacggca cgatggtcga tcgccgtggt tcggtggcga ttgatgacga
    23281 aggtacgcca ggccagtaca acgtgctgat tgagaacggc attctgaaag gctacatgca
    23341 ggataaactc aacgcgcgtt tgatggggat gacgccgact ggcaacggtc gccgtgaatc
    23401 ctacgctcat ctgcccatgc cgcgtatgac taatacctat atgctgccgg gtaaatcgac
    23461 cccgcaggaa attattgaat ccgttgagta cggtatctat gcaccgaact ttggtggcgg
    23521 tcaggtggat atcacctccg gcaaattcgt tttctccacc tcagaagcgt atctgattga
    23581 aaacggtaaa gtaacgaagc cggtgaaagg cgcaacgttg attggttccg gtatcgaaac
    23641 catgcagcag atttcgatgg ttggcaacga cctgaaactg gataacggcg tgggtgtctg
    23701 cggtaaagaa gggcaaagtt tgccggttgg cgtgggccag ccaacgctga aagttgataa
    23761 cctgactgtt ggcggtactg cgtaataatt tcagtatttt cagaaggata attaatcctt
    23821 ctccgtgtac gaacggtccc ctcgcccctc tggggttagg gggaggggaa cccgttggca
    23881 caggtttgta ctacgtaaca gtacaatatt aattacttct ctttcccgcg cccgtgcatc
    23941 tcctgaaaca atttaccgac ctcaacaaaa taatccgtta gcgagttgat cacgacttgt
    24001 accttcagcg gcagcttatc tttttcggta tataacgcat aaaccgggcg tggatctgac
    24061 tgataacgcg gcagcaggat ctccagctcc ccacgattga tctcgttgat cacccacatc
    24121 agcggcacgt aggcgatccc ggcacccgcc gtcagccagc gcaccagcgt catcggatca
    24181 ttagtcacaa atcttccttg tgggatcagg cgagtcgaga tcccttccgg tgcgatcagt
    24241 tcaaattcat tgtcgggccg cacgctgtat tcaagccatg aatgactact caaatcggcg
    24301 ggtttttccg gtatgccgta ttgtgtgaga tagcttttcg cggcgcacac caccatcggc
    24361 atcgcgccca gacggcggga aaacaggctg gaatcctgca acgcgccgac gcggatcacc
    24421 acatccagac catcggcaat caggtcgggg gcaggaattc cggtaaccag attgacgctc
    24481 aaacctgggt attctttcag catttttgct gtcagcccgg cgagaacatt ttgtgccata
    24541 gttgaagaac agccaatgcg cagcgtcccg atgggggtgt tattgaaggc atacagttgc
    24601 tcatgaacat cctgcacttc atggagcatc cgacggcagc cctggtagta aattctaccg
    24661 gcttcggtca ggccaatgct gcgtgtgcta cggtttaaca gctttacctg caactcatct
    24721 tccagttttg acaccgtctg actgatggac gaaacgctca tctgtagctg tctggcggcg
    24781 gcggtaaaag agccaaattc aactactttg gcaaacaccg acatgcgttt tagtcgttcc
    24841 attattcact ctgacttaaa agtgatttag atcacataat atagataaca gcataacagt
    24901 tacgctaata tattaaatat caatctacag caatgttgct ctcgcccggc tttccatgcc
    24961 cttctctgcg gcgacagatg ctgaaaataa taacgcctgc tctctctata caaccaaggt
    25021 caacatgagt ctgtttcccg ttatcgtggt gtttgggctg tccttcccac cgatattttt
    25081 cgaattgctt ttatcactgg cgattttctg gctggtgcgc cgggtacttg tgccaacagg
    25141 tatctacgac tttgtctggc atccggcgtt gttcaacacc gcgctctatt gctgcttgtt
    25201 ttatttgata tcgcgactgt tcgtttgagg ttgaagtgaa aacactaata agaaaattct
    25261 cccgtacggc catcacggtc gtattagtca ttctggcctt catcgcaatt tttaatgcct
    25321 gggtctatta caccgaatcc ccctggacgc gtgacgcgcg ctttagcgct gacgtcgttg
    25381 cgatcgcgcc ggacgtttct ggacttatca cccaggtgaa tgttcatgat aaccagctgg
    25441 tgaaaaaagg acaggtactg ttcatcatcg accagccgcg ctatcaaaag gcgcttgagg
    25501 aagcgcaagc cgatgttgct tattatcagg tactggcaca ggagaaacgc caggaggccg
    25561 gacgtcgtaa ccgtctcggt gtgcaggcga tgtctcgcga agagatcgac caggccaaca
    25621 acgtactaca aacggttctg catcagttag cgaaagcgca ggcgacccgc gatctggcaa
    25681 aactggatct tgaacgtaca gtcatccgcg cgccagcaga tggctgggtg accaacctca
    25741 acgtctatac cggtgagttt attacccgtg gatcaacggc ggttgcgctg gtgaaacaga
    25801 actctttcta tgtactggcc tatatggaag aaaccaagct ggaaggggtg cgccctgggt
    25861 atcgtgcgga gatcacgccg cttggcagta acaaagtgct gaaagggact gttgatagtg
    25921 ttgccgctgg ggtcaccaac gccagcagca cgcgtgacga caaagggatg gcgaccatcg
    25981 actctaacct tgaatgggta cgtttggcgc aacgtgttcc ggtacgtatt cgtctcgaca
    26041 accagcaaga gaacatctgg cctgcgggca ccactgctac agtggtggtc actggcaaac
    26101 aagatcgcga cgaaagccag gattcgttct tccgtaaaat ggcccatcgc ctgcgtgagt
    26161 ttggttaatc acgatgggta ttttctccat tgctaatcaa catattcgct ttgcggtaaa
    26221 actggcgacc gccattgtac tggcgctgtt tgttggcttt cacttccagc tggaaacgcc
    26281 acgctgggcg gtactgacag cggcgattgt tgccgccggt ccggcctttg ctgcgggagg
    26341 tgaaccgtat tctggcgcca ttcgctatcg tggctttttg cgcatcatcg gcacatttat
    26401 tggctgtatt gccggactgg taatcatcat tgcgatgatc cgcgcaccat tattgatgat
    26461 tctggtgtgc tgtatctggg ccggtttttg tacctggata tcctcgctgg tacgaataga
    26521 aaactcgtat gcgtgggggc tggcaggtta taccgcgctg atcattgtga tcactattca
    26581 gccggaacca ttgcttacgc cgcagtttgc cgtcgaacgt tgtagcgaga tcgttatcgg
    26641 tattgtgtgt gcaattatgg cggatttgct cttttctccg cgatcgatca aacaagaagt
    26701 ggatcgagag ctggaaagtt tgctggtcgc gcaatatcaa ttaatgcaac tctgtatcaa
    26761 acatggcgat ggtgaagttg tcgataaagc ctggggcgat ctggtgcgac gtactacggc
    26821 gttacaaggt atgcgcagca acctgaatat ggaatcttcc cgctgggcgc gggccaatcg
    26881 acgtttaaaa gcgatcaata cgctatcgct gacgctgatt acacaatcct gcgaaactta
    26941 tcttattcag aatacgcgcc cggaattgat cactgatact ttccgcgaat tttttgacac
    27001 gccggtagaa accgcgcagg acgtccacaa gcagctcaaa cgcctgcgga gagtgatcgc
    27061 ctggaccggg gaacgggaaa cgcctgttac catttatagc tgggtcgcgg cggcaacgcg
    27121 ttatcagctt ctcaagcgcg gcgttatcag taacacaaaa atcaacgcca ccgaagaaga
    27181 gatcctgcaa ggcgaaccgg aagtcaaagt agagtcagcc gaacgtcatc atgcgatggt
    27241 taacttctgg cgaaccacac tttcctgcat tctggggacg cttttctggc tgtggacggg
    27301 ctggacttcc ggcagtggtg caatggtgat gattgcggta gtgacgtcac tggcaatgcg
    27361 tttgccaaat ccacgcatgg tggcgatcga ctttatctac gggacgctgg ccgcgctgcc
    27421 gttagggctg ctctactttt tggtgattat ccctaatact caacagagca tgttgctgct
    27481 gtgtattagc ctggcagtgc tgggattttt cctcggtata gaagtacaga aacggcgact
    27541 gggctcgatg ggggcgctgg ccagcaccat aaatattatc gtgctggata acccgatgac
    27601 tttccatttc agtcagtttc tcgacagcgc attagggcaa atcgtcggct gtgtgctcgc
    27661 gttcaccgtt attttgctgg tgcgggataa atcgcgcgac aggactggac gtgtactgct
    27721 taatcagttt gtttctgccg ctgtttccgc gatgactacc aatgtggcac gtcgtaaaga
    27781 gaatcacctc ccggcacttt atcagcagct gtttttgctg atgaataagt tcccagggga
    27841 tttgccgaaa tttcgcctgg cactgacgat gattatcgcg caccagcgcc tgcgtgatgc
    27901 gccgatcccg gttaacgagg atttatcggc gtttcaccgg caaatgcgcc gcacagcaga
    27961 ccatgtgata tctgcccgta gcgatgataa acgtcgtcgg tactttggcc agttgctgga
    28021 agaactggaa atctaccagg aaaagctacg catctggcaa gcgccaccgc aggtgacgga
    28081 accagtacat cggcttacgg gtatgctcca taagtatcaa catgcgttga ccgatagtta
    28141 agtcaaaacc gacgccaaaa gcgtcggttt tttcatggct atacttagca atgaacggca
    28201 gaactcgccg cgaaacgtga cggtggcaac agatgaatat ttataccttt gattttgatg
    28261 agattgagag tcaggaggat ttttatcgcg actttagcca aacctttggt ctggcaaaag
    28321 ataaagtacg cgatctcgac tctctatggg atgtgttaat gaacgatgtc ctgccgctac
    28381 cacttgagat tgaatttgtt catctgggag agaaaacacg tcgccgtttt ggcgcgttaa
    28441 tattgctgtt tgatgaggca gaggaagagc tggaagggca tttgcgtttt aatgttcgtc
    28501 attagcgcaa aaaaaaagcc cccgaaccgg gggcaatatc gtcggacaag acgatgaggg
    28561 tttatttgta cagttcagcc gtagcgtgcc aggtgtcacc gctacgagct tccgtaatct
    28621 ggtaggccgt tgcgcctttc tcttctgctt ttttgttcag catttcacgc atatccattg
    28681 gcgaagacgc cacaccactt acggatacgg tcccgattgc ttcacgattt tgtgcttgtg
    28741 cagcatcaat ggagtcggca gcgaatgcac cgaaagagag aacagaaagt acgcttaatg
    28801 cagcaacagt ggttttgatt ttcatgattt ttacctcgac ataatctttt agctgggcct
    28861 ttgtttcgtg acccatatca caaaatcaag tatacactaa ttattgaact aattaatacc
    28921 acgctaactg tttcagttga tactaagtgt taaaaatgtg aattttaata acaaaaaaga
    28981 attaaaaaca cggttattta tttttaattc tagtattttc aattagataa tgaattttgc
    29041 ataatgtgct ttttttaccg tatgtattca ttgtgtgaat gacatgtcgc agtaaaacgc
    29101 actattcgtt aaatcaatcg caggggaaag caggggggtg agagggataa gcaacatttt
    29161 ccccgccgcc agaagcgacg gggcagagat taaagctcct ggtcgaacag ctctaaaatc
    29221 gcttcgtaca ggtctttgac ggtgaaaccg ttagcagggg tggtaaagat ggtgtcatcg
    29281 ccagcgatgg tgcccagaat accttctgct ttgcccagtg aatccagcag gcgagcaatt
    29341 aactgcgccg cgccagggct ggtatgaatc acgacaactg catcgttgta gtcgatatcc
    29401 agcaccagat ttttcaatgg actggaggtg gttggtacac ccagttcagc tggcaggcag
    29461 taaaccattt ccattttggc attgcgtgta cgtacagcac caaacttggt caacatccgc
    29521 gagactttag actgattaat attgtcaaag ccttgctcct gcaacgcggc gacgatttcg
    29581 ccctgggagc taaatttctc ttctttaagt aatgctttaa atgctttaac tagttcttct
    29641 tgcttagccg agcttcgcat aagtcacccg atatggtggt tgatacaaca ttattgtgca
    29701 tacagatgaa tttttatgca aacagtcagc cctgaagaag gctgaaataa tgttatgaaa
    29761 gagcgggatt ttatcaaatt tcgttattga gaaacatgcc tgcgtcacgg catgcaaatt
    29821 ctgcttaaaa gtaaattaat tgttatcaaa ttgatgttgt tttggctgaa cggtagggta
    29881 tattgtcacc acctgttgga atgttgcgct aatgcataag cgactgttaa ttacgtaagt
    29941 taggttcctg attacggcaa ttaaatgcat aaacgctaaa cttgcgtgac tacacattct
    30001 tgagatgtgg tcattgtaaa cggcaatttt gtggattaag gtcgcggcag cggagcaaca
    30061 tatcttagtt tatcaatata ataaggagtt taggatgaaa gtcgcagtcc tcggcgctgc
    30121 tggcggtatt ggccaggcgc ttgcactact gttaaaaacc caactgcctt caggttcaga
    30181 actctctctg tatgatatcg ctccagtgac tcccggtgtg gctgtcgatc tgagccatat
    30241 ccctactgct gtgaaaatca aaggtttttc tggtgaagat gcgactccgg cgctggaagg
    30301 cgcagatgtc gttcttatct ctgcaggtgt agcgcgtaaa ccgggtatgg atcgttccga
    30361 cctgtttaac gttaacgccg gcatcgtgaa aaacctggta cagcaagttg cgaaaacctg
    30421 cccgaaagcg tgcattggta ttatcactaa cccggttaac accacagtgg cgattgctgc
    30481 tgaagtgctg aaaaaagccg gtgtttatga caaaaacaaa ctgttcggcg ttaccacgct
    30541 ggatatcatt cgttccaaca cctttgttgc ggaactgaaa ggcaaacagc caggcgaagt
    30601 tgaagtgccg gttattggcg gtcactctgg tgttaccatt ctgccgctgc tgtcacaggt
    30661 tcctggcgtt agttttaccg agcaggaagt ggctgatctg accaaacgta tccagaacgc
    30721 gggtactgag gtggttgaag cgaaagccgg tggcgggtct gcaaccctgt ctatgggtca
    30781 ggcagctgca cgttttggcc tgtctctggt tcgcgcactg caaggtgaac aaggcgttgt
    30841 cgaatgtgcc tacgttgaag gtgacggtca gtacgcacgt ttcttctctc aaccgctgct
    30901 gctgggtaaa aacggcgtgg aagagcgtaa atctatcggc actctgagcg catttgaaaa
    30961 gaacgcgctg gaaggtatgc tggatacgct gaagaaagat atcgctctgg gcgaagagtt
    31021 cgttaataag taattgatta gcggataata aaaaaccgga gcacagactc cggttttttg
    31081 ttttgagcgc acgacttaat tggttgccgg atattcctga atggtgacct gcagcgttaa
    31141 ctgcttatca tcacgcatca ctacaaccgg gatcaccgag ccagggcgaa tttccgccac
    31201 ctgatccatc gtctccagag cagagatggc cggtttgtta tccaccgaaa taatcaaatc
    31261 attgacctga atacccgcat tcgccgccgg gccgtcaggt gacacttcat taaccacgat
    31321 cccttgcagt tgatctatac caccgccctg cgcgtgcagt ggtgcgatct cacgtccgcc
    31381 gataccaatg tagccgcgga tcacgcgacc atcgcggatc agtttatcca taattttggt
    31441 tgctaactgg aaaggaatcg caaagccgat accttccggc gtttcgccat cgttactctt
    31501 atcaaacgac agcgtgttaa tgcccatcag ttcgcccagc gagttcacca gcgcgccgcc
    31561 agagttaccg tggttaatgg aagcatcagt ttgcaggaag ttttgccgcc cggtcgggtt
    31621 cagaccgatt cgacccgtgg cactaataat cccctgggta atggtctgcc cgaggttgta
    31681 cgggttaccg atcgccagta ccacgtcgcc aatgtgcggt acgcgacgtg cattaattgg
    31741 aatggtaggt aaaccgccag tggcattaat tttaagtacc gccagatcgg ttagagagtc
    31801 agatcccacc agcaatgctt caaatacacg tccatcctgt aaggcgacga tgatctgatc
    31861 ggcgtcgttg atgacgtgtt tattggtgat gatataaccg cgttgatcca tgattacacc
    31921 ggatcccagg gtgcggatct caagctggtt gtgagagttg gtgttcaaac cacggttgta
    31981 aacgttaacc accgctggcg cggcgcggcg aaccgccaga ttatagctgg caggcgtctc
    32041 atcggtactg tcaaattgcg gagtggaaag cgggttaagg ctgcgcagcg aaggcatggc
    32101 aaccagcaga atagcgccga caattaatcc aatcgcaacg gaacgtaaga gcttcacaaa
    32161 catgatggag gcgtcattaa aaaagggaac ggcagcagca taccacgagt taaccggaca
    32221 tcacacgtca gcctgatgcc cggtttacga cattaacgca tcagcagata gatgctttca
    32281 ttgccgcgta caatttgcag ggcgatgatg gccggttttg ccgccagcac tttacgcatt
    32341 tcagcaatcg agttcacccg atcgcggttg acgccaatga tcacatcgtc tttttgcaag
    32401 ccagcctgag cagctgggct tcctttgaca acctcatcga tcttaatacc tttgccgcca
    32461 tcttttagct gaccatcgct caacgttgca ccttccagcg ctggcgtgat catttcagcg
    32521 ctggccgacg aagaggtgct ggtatcgagc gtcacttcta cttccagtgg tttgccgtta
    32581 cgcagcaggc caagtttcac ttttgtgccc ggctcggtgg tcgcgatacg agagcgcaac
    32641 tcagcaaagc tattcagcgg tttgccgttg aggctggtaa taatatcgcc cgctttgacg
    32701 cccgctttcg ccgagccaga acctggcaac acttcgctga caaacgcgcc acgctgcacg
    32761 tcaaggttga aggctttggc gatatcggca ctcatctcgg tgcctttgat gcctaacaaa
    32821 ccgcgtttga tttcaccaaa gtcgataagc tgctgcgcca gtgttcgcgc catattactg
    32881 gggatggcaa atccaatccc gacgctcccg ccgccaggcg caaggattgc agtgttgatg
    32941 ccaattaact cgccgttaag gtttaacagt gcaccgccgg agttaccgcg gttaatggaa
    33001 gcatctgtct ggataaagtt ttccagacct tcaagattca acccgctgcg gcctaatgcg
    33061 gaaacaatgc cagaggtggc ggtttgccca aggccaaatg ggttaccgac cgccacggca
    33121 aaatcaccga cgcgcaattt atcggagtcg gcaatagcga tttgcgttaa tttgctcggg
    33181 ttttgaattt gtaacagggc gatatcgctc tggtcatcgc taccaatcag ttttgcatca
    33241 aactcgcgcc catcattgag ctgaatactg attttctgtg cctgattaat cacatggttg
    33301 ttggtcagca catagccttt actggcgttg atgatgacac cggagcctaa accttcgaag
    33361 ggttgtgcag gttgatccgg taaatcatca ccaaaaaact ttttgaattc ttccgggatt
    33421 ttctgtccct gactggccgt tccttccacc cgtacgctca ccactgccgg aagcactttt
    33481 tccagcattg gggccagact ggggagaggg gcctgatcgg caacttggcc tggaatcgac
    33541 gcaacggcct gaaatgacgc cgagagagtt aacccgacac ttaacgctaa tgcactcaac
    33601 agctgggttt gttttttcat tattcctgct ctcgtacctg aatgataaga aaagagattc
    33661 aaaacagttt gatgttattg aattttcaga cggctaacaa tgagacacca gattaaatga
    33721 tagtcgggga gggagagaag aggagggcgc aatggctgcg cccgaaaaat aaattagtcg
    33781 cgcttcgcgc cagtacgcag caggccggat gcgccttcag aatagtcgcg aggcatttgc
    33841 accggtgcct gatcgttgct ggcttcagac tctgccagac gattacggaa cgggtttgct
    33901 tcagcagaca gttccggcag caggctgctg gagcttttcg ccatgtgttg atacagctgg
    33961 cgatagtcgt gcgccatggt atccagtaat tccgcgctgc gggcaaagtg gctaaccagc
    34021 tcttcgcgat actcgtccag ttcagcttta ttcttttcca gttcgtactg caacgcctgt
    34081 tgctggcgta gtttacgatt accaaaacgc atggccacag caccaataat gatgccgacg
    34141 actaacccaa ttagcgcata ttcccaggtc atgaacatct cccgttgtct tttgtttccg
    34201 tagggtgttg gcttcaggct ccatgcctgc ggctgattat gccactataa ccgttaattc
    34261 cacagaagtg gaatcccgac tgcatatcgc gtagtgtaga acggcctttt tttcgtcaac
    34321 cgtgaacaac ggcgcaccga ttattcaagg aataacaata agatcatgca aagcattacc
    34381 ccaacatcgc aatacctgaa ggcgctcaat gaaggcagcc atcaacccga cgacgttcaa
    34441 aaagaggccg tcagccgcct ggaaattatt tatcaggaac tcatcaatag cacgccacca
    34501 gcccccagga cgagtgggct aatggcgcgg gtcggtaagc tgtggggtaa acgcgaagac
    34561 acaaagcata cgccagtgcg tggcttatat atgtggggcg gggtaggacg cgggaaaacc
    34621 tggctgatgg accttttcta tcaaagcctg ccgggagagc ggaaacagcg tctgcacttt
    34681 caccggttta tgctgcgggt acatgaagag ctaactgctt tgcaggggca gaccgatccg
    34741 ctggaaatta ttgccgatcg ctttaaagca gaaactgacg tgctctgttt tgacgaattt
    34801 tttgtttctg atattaccga cgccatgcta cttggcggcc tgatgaaagc cctgttcgct
    34861 cgcggaataa cgctggtagc gacgtcaaat attccgccgg acgaacttta tcgaaatggc
    34921 ctacaacgtg cgcgtttttt gcctgcaatc gatgccatta aacagcattg tgatgtaatg
    34981 aacgtggacg ctggtgttga ttatcgactg cgtacactca ctcaggcgca tctgtggctt
    35041 tcgcccctca acgatgaaac ccgggcgcaa atggataaac tatggttggc gctggcgggg
    35101 gcgaaacgag aaaattcacc gacattagaa atcaaccatc ggccattggc gacaatgggc
    35161 gtcgagaacc agacgctggc ggtctctttt actacgctgt gcgtcgacgc ccgcagtcag
    35221 catgactata ttgcgctctc acgcctcttt cacacggtca tgttgtttga tgtaccagtt
    35281 atgacgcggt tgatggagag cgaagcgcgg cgctttattg cgctggtgga tgagttttac
    35341 gagcgccatg tcaaattagt ggtgagtgca gaagtgccgc tatatgacat ttatcagggc
    35401 gagcggctga aatttgagtt ccagcgttgc ctgtcacgtc tgcaagagat gcaaagcgaa
    35461 gagtatctga agcgcgagca tttagcgggt taaaacctgc cacaaatcac aaaaaggggt
    35521 cgatctttga ccccgacttc tctataatcc tgcgacccca cgttacaaga aagttttttt
    35581 cccaaaactt tttgtgtgct ggcataggct attcgaaggg gtaggtttgc cggactttgt
    35641 cgtgtgaacc tcaacaattg aagacgtttg ggtgttcacc aacgtgtaac tatttattgg
    35701 gtaagctttt aatgaaaact tttacagcta aaccagaaac cgtaaaacgc gactggtatg
    35761 ttgttgacgc gaccggtaaa actctgggcc gtctggctac tgaactggct cgtcgcctgc
    35821 gcggtaagca caaagcggaa tacactccgc acgtagatac cggtgattac atcatcgttc
    35881 tgaacgctga caaagttgct gtaaccggca acaagcgtac tgacaaagtg tactatcacc
    35941 acaccggcca catcggtggt atcaaacaag cgacctttga agagatgatt gctcgccgtc
    36001 ctgagcgtgt gattgaaatc gcggttaaag gcatgttgcc aaaaggcccg ctgggtcgtg
    36061 ctatgttccg taaactgaaa gtttacgcgg gtaacgagca caaccacgcg gcacagcaac
    36121 cgcaagttct tgacatctaa tcgggattat aggcaatggc tgaaaatcaa tactacggca
    36181 ctggtcgccg caaaagttcc gcagctcgcg ttttcatcaa accgggcaac ggtaaaatcg
    36241 taatcaacca acgttctctg gaacagtact tcggtcgtga aactgctcgc atggtagttc
    36301 gtcagccgct ggaactggtc gacatggttg agaaactgga cctgtacatc accgttaaag
    36361 gtggtggtat ctctggtcag gctggtgcga tccgtcacgg tatcacccgc gctctgatgg
    36421 aatacgacga gtccctgcgt tctgaactgc gtaaagctgg cttcgttact cgtgacgctc
    36481 gtcaggttga acgtaagaaa gtcggtctgc gtaaagcacg tcgtcgtccg cagttctcca
    36541 aacgttaatt ggcttctgct ccggcagaaa acaatttgcg aaaaaacccg cttcggcggg
    36601 tttttttatg gctaaattct gaatcagcgt aaaaaatgga aagttgcttt ttgctgccgt
    36661 ctgacaacag gcaaaacaaa aaccacatcg ccaataaggg actaagtcaa ctatttcaga
    36721 ctaaagcgca tctctttttc cccatttccg gcatcgactc accacaaagg tcgcaaaatc
    36781 tggtaaacta tcatccaatt ttctgcccaa atgtcgggta ttgctcattt tttgtttgat
    36841 tttcgaacaa agagagtcgt tccttactgg gtaacacaac ttctgactgg ccacctggtg
    36901 gctggtagca gtaaaaattc tgactatacc tggaggtttt catggctgtc gctgccaaca
    36961 aacgttcggt aatgacgctg ttttccggtc ctactgacat ctatagccat caggtccgca
    37021 ttgtgctggc tgagaaaggt gtaagtttcg agatcgaaca cgtggaaaag gacaatccgc
    37081 ctcaggatct gattgacctc aacccgaatc agagcgttcc gaccctggtg gatcgtgagc
    37141 tgaccctgtg ggaatctcgc atcattatgg aatatctgga tgagcgtttc ccgcatccgc
    37201 cactgatgcc tgtttacccg gtagctcgcg gtgaaagccg tctgtacatg catcgcatcg
    37261 aaaaagactg gtacacgctg atgaacacca tcatcaacgg ttcagcttct gaagcagatg
    37321 ccgcacgtaa gcaactgcgc gaagaactgc tggcgattgc gccggtcttc ggccagaagc
    37381 cgtacttcct gagcgatgaa ttcagcctgg tcgattgcta ccttgctccg ctgctgtggc
    37441 gtctgccgca actgggtatc gagttcagcg gcccgggtgc gaaagagctg aaaggctata
    37501 tgacccgcgt ctttgagcgt gactctttcc ttgcttcttt aactgaagct gaacgtgaaa
    37561 tgcgtctggg ccggagttaa tctgtatgga tttgtcacag ctaacaccac gtcgtcccta
    37621 tctgctgcgt gcattctatg agtggttgct ggataaccag ctcacgccgc acctggtggt
    37681 ggatgtgacg ctccctggcg tgcaggttcc tatggaatat gcgcgtgacg ggcaaatcgt
    37741 actcaacatt gcgccgcgag ctgtcggcaa tctggaactg gcgaatgatg aggtgcgctt
    37801 taacgcgcgc tttggtggca ttccgcgtca ggtttctgtg ccgctggctg ccgtgctggc
    37861 tatctacgcc cgtgaaaatg gcgcaggcac gatgtttgaa cctgaagctg cctacgatga
    37921 agatgccagc atcatgaatg atgaagaggc atcggcagac aacgaaaccg ttatgtcggt
    37981 tattgatggc gacaagccag atcacgatga tgacactcat cctgacgatg aaccaccgca
    38041 gccaccacgt ggtggtcgac cagcattacg cgttgtgaag taatactaaa acaggccctg
    38101 gcggcctgtt ttgtcttttt aatcgcttaa taaaatagcg tgatagtggc aatcatattc
    38161 accacgaaac cgactgccat ggggatcgct gtccgcttca ctaccgcaaa aggcgaaacg
    38221 cctgcaattc ctgacgtaac gaccaccacc gcagtaatcg gcgaaacagc gcgcgctaac
    38281 gtcgtggcaa aatgcatcgg cataatcatt acaaccgctg gtacatgtag tccggctgcg
    38341 atattcggaa taagactggc aaatgacata aacggcgcat tgcctgagcc catcacgatg
    38401 gcacaaatgg caatgaccag cgccataata atcatcacgc caataccgcc cagaccagaa
    38461 tgctccgccc ccctgataac cgcatcgaca gtgccaatcg tcgttaagcc tttcgcaaat
    38521 atttcacccg cgaccaccag cgttaccacg ttggcaaact gcgtacccat gccgtcaaaa
    38581 aacgcctgca catcgtccat tgtttcgcgc aagttatgct tgcggaagaa ctcaacaaac
    38641 atcgtcaccg tcaaactcag taacatcacc accaccagat gcagttctga ctgcatcagc
    38701 ccgacgtggg caaggaacag cgagccgagc atcaggatta acggcatcac cggtaaaatg
    38761 gcgtaataga gcggtgggac attatcgaga gctttttgct ctgcctgttc gtgattgata
    38821 tttttatctt ttttgtcgaa agcgcgttgc acgaaaaagt gggagatcgc caccgagata
    38881 atgacgcaag aggcgaccgg aagctggtag tggaagaagt aagtggcaat tttcattcct
    38941 gcgacctggg cagcaaaaat ggagttcgtt tccagaatcc cccactcaat ggacatggtg
    39001 gttgcgataa ccgccaccgc agagagacga cttactccca gactcaccag cgtcggaaat
    39061 aaggtgacca tcagcaacat acccagaccg gaggcgctgg taataaactg cgccatgatt
    39121 tggccgatga cgtaagttgc cgacagaata atatacggcg agcgaatgag ttttaacggg
    39181 cggcttaaca agctcaccat cgcgcgactt gcccctatgc gctccatata gcgggcataa
    39241 ccgcccactg ccataatcga cagccccaat ccggcaatgc ggttggacag catgcgcagg
    39301 atttcattat aaatatcgac gatcaagtag ccgctgcttt tggcgggatc gagcacacca
    39361 ccgaacccta accagacacc gcacatcatc aggaagatac ctgcggcagc cagcaccacc
    39421 tgaggtttgt agtttttcag gatcaaatag cccatcgtaa ttaatacgat gacagatata
    39481 attatgccga acattgttga actccgtgtc aaaagaaaac ggtcaatccc ataaacggca
    39541 gattgaaaac aatgatgtta tattttttgc aaggctattt atggtgcgga tgtcgtgttt
    39601 ttaattgtag a
//
LOCUS       DADXDL010000037        39020 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.037, whole genome shotgun sequence.
ACCESSION   DADXDL010000037 DADXDL010000000
VERSION     DADXDL010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 39020)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39020)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39020
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.037"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..388)
                     /locus_tag="IRB70_002232"
     CDS             complement(<1..388)
                     /locus_tag="IRB70_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBC0632142.1"
                     /translation="MINNISDQVSSFPGTQLNQSDNFLDSLREFFAILNSSRKGELST
                     WDTIYLHLILAINADSDLIKNDELLAENIPSANYQFNIFFSNAFEIDVKKYLGKSEDN
                     EVEIKVGNERITIGIRNVSNGKLERQK"
     gene            1036..1551
                     /locus_tag="IRB70_002233"
     CDS             1036..1551
                     /locus_tag="IRB70_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBC0632143.1"
                     /translation="MRYRSLSLLIPCALLLSACTTVTPAYKDNGPRTGSCVQGGPDSV
                     AQQFYDYRIQHRSNDITALRPYLSDKLATLLSDASRDNSHRELLSSDPFSSRTTLPDS
                     AHVASASTIPNRDARNIPLRVDLKQGDQGWQDEVLMIQEGQCWVIDDVRYLGGSVHAT
                     AGTLRQSIENR"
     gene            1769..2497
                     /gene="artP"
                     /locus_tag="IRB70_002234"
     CDS             1769..2497
                     /gene="artP"
                     /locus_tag="IRB70_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter ATP-binding protein
                     ArtP"
                     /protein_id="HBC0632144.1"
                     /translation="MSIQLNGINCFYGAHQALFDITLDCPQGETLVLLGPSGAGKSSL
                     LRVLNLLEMPRSGTLNIAGNHFDFTKTPSDKAIRDLRRNVGMVFQQYNLWPHLTVQQN
                     LIEAPCRVLGLSKDQALARAEKLLERLRLKPYSDRYPLHLSGGQQQRVAIARALMMEP
                     QVLLFDEPTAALDPEITAQIVSIIRELAETNITQVIVTHEVEVARKTASRVVYMENGH
                     IVEQGDASCFTEPQTEAFKNYLSH"
     gene            2515..3246
                     /gene="artJ"
                     /locus_tag="IRB70_002235"
     CDS             2515..3246
                     /gene="artJ"
                     /locus_tag="IRB70_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter substrate-binding
                     protein"
                     /protein_id="HBC0632145.1"
                     /translation="MKKVLIAALIAGFSLSATAAETIRFATEASYPPFESIDANNQIV
                     GFDVDLAQALCKEIDATCTFSNQAFDSLIPSLKFRRVEAVMAGMDITPEREKQVLFTT
                     PYYDNSALFVGQQGKYTSVDQLKGKKVGVQNGTTHQKFIMDKHPEITTVPYDSYQNAK
                     LDLQNGRIDSVFGDTAVVTEWLKDNPKLAAVGDKVTDKDYFGTGLGIAVRQGNTELQQ
                     KLNTALEKVKKDGTYETIYNKWFQK"
     gene            3253..3969
                     /gene="artQ"
                     /locus_tag="IRB70_002236"
     CDS             3253..3969
                     /gene="artQ"
                     /locus_tag="IRB70_002236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtQ"
                     /protein_id="HBC0632146.1"
                     /translation="MNEFFPLASAAGMTVGLAVCALIVGLALAMFFAVWESAKWRPVA
                     WAGSALVTVLRGLPEILVVLFIYFGSSQLLLTLSDGFTINLGFVQIPVQMDIENFDVS
                     PFLCGVIALSLLYAAYASQTLRGALKAVPVGQWESGQALGLSKSAIFFRLVMPQMWRH
                     ALPGLGNQWLVLLKDTALVSLISVNDLMLQTKSIATRTQEPFTWYIVAAAIYLVITLL
                     SQYILKRIDLRATRFERRPS"
     gene            3969..4637
                     /gene="artM"
                     /locus_tag="IRB70_002237"
     CDS             3969..4637
                     /gene="artM"
                     /locus_tag="IRB70_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine ABC transporter permease ArtM"
                     /protein_id="HBC0632147.1"
                     /translation="MFEYLPELMKGLHTSLTLTVASLIVALILALIFTIILTLKTPVL
                     VWLVRGYITLFTGTPLLVQIFLIYYGPGQFPTLQEYPALWHLLSEPWLCALIALSLNS
                     AAYTTQLFYGAIRAIPEGQWQSCSALGMSKKDTLAILLPYAFKRSLSSYSNEVVLVFK
                     STSLAYTITLMEVMGYSQLLYGRTYDVMVFGAAGIIYLIVNGLLTLMMRLIERKALAF
                     ERRN"
     gene            4863..5594
                     /gene="artJ"
                     /locus_tag="IRB70_002238"
     CDS             4863..5594
                     /gene="artJ"
                     /locus_tag="IRB70_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein ArtJ"
                     /protein_id="HBC0632148.1"
                     /translation="MKKLVLAALLASFTFGASAAEKINFGVSATYPPFESIGANNEIV
                     GFDIDLAKALCKQMQAECTFTNHAFDSLIPSLKFRKYDAVISGMDITPERSKQVSFTT
                     PYYENSAVVIAKKDTYKTFADLKGKRIGMENGTTHQKYIQDQHPEVKTVSYDSYQNAF
                     IDLKNGRIDGVFGDTAVVNEWLKTNPQLGVATEKVTDPQYFGTGLGIAVRPDNKALLE
                     KLNNALAAIKADGTYQKINDQWFPQ"
     gene            complement(5623..6750)
                     /gene="rlmC"
                     /locus_tag="IRB70_002239"
     CDS             complement(5623..6750)
                     /gene="rlmC"
                     /locus_tag="IRB70_002239"
                     /EC_number="2.1.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(747)-C(5))-methyltransferase
                     RlmC"
                     /protein_id="HBC0632149.1"
                     /translation="MQCALYDAGRCRSCQWITQPIPEQLSAKTADLKNLLADFPVEEW
                     CAPVSGPEQGFRNKAKMVVSGSVEKPLLGMLHRDGTPEDLCDCPLYPASFAPVFAALK
                     PFIARAGLTPYNVARKRGELKYILLTESQSDGGMMLRFVLRSDTKLAQLRKALPWLQE
                     QLPQLKVITVNIQPVHMAIMEGETEIYLTEQQALAERFNDVPLWIRPQSFFQTNPAVA
                     SQLYATARDWVRQLPVKHMWDLFCGVGGFGLHCATPDMQLTGIEIAPEAIACAKQSAA
                     ELGLTRLQFQALDSTQFATAQGEVPELVLVNPPRRGIGKPLCDYLSTMAPRFIIYSSC
                     NAQTMAKDIRELPGYRIERVQLFDMFPHTAHYEVLTLLVKQ"
     gene            complement(6791..7279)
                     /locus_tag="IRB70_002240"
     CDS             complement(6791..7279)
                     /locus_tag="IRB70_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjO family protein"
                     /protein_id="HBC0632150.1"
                     /translation="MEDETLGFFKKTSSSHARLNVPALVQVAALAIIMIRGLDVLMIF
                     NTLGVRGIGEFIHRSVQTWSLTLVFLSSLVLVFIEIWCAFSLVKGRRWARWLYLLTQI
                     TAASYLWAASLGYGYPELFSIPGESKREIFHSLMLQKLPDMLILMLLFVPSTSRRFFQ
                     LQ"
     gene            complement(7339..8184)
                     /gene="potI"
                     /locus_tag="IRB70_002241"
     CDS             complement(7339..8184)
                     /gene="potI"
                     /locus_tag="IRB70_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotI"
                     /protein_id="HBC0632151.1"
                     /translation="MNNLPVVRSPWRIVILLLGFTFLYAPMLMLVIYSFNSSKLVTVW
                     AGWSTRWYGELLRDDAMMSAVGLSLTIAACAATAAAILGTIAAVVLVRFGRFRGSNGF
                     AFMITAPLVMPDVITGLSLLLLFVALAHAIGWPADRGMLTIWLAHVTFCTAYVAVVIS
                     SRLRELDRSIEEAAMDLGATPLKVFFVITLPMIMPAIISGWLLAFTLSLDDLVIASFV
                     SGPGATTLPMLVFSSVRMGVNPEINALATLILGAVGIVGFIAWYLMARAEKQRIRDIQ
                     RARRG"
     gene            complement(8181..9134)
                     /gene="potH"
                     /locus_tag="IRB70_002242"
     CDS             complement(8181..9134)
                     /gene="potH"
                     /locus_tag="IRB70_002242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter permease PotH"
                     /protein_id="HBC0632152.1"
                     /translation="MSTLEPAAQSKPPGGFKLWLSQLQMKHGRKLVIALPYIWLILLF
                     LLPFLIVFKISLAEMARAIPPYTELMEWADGQLSITLNLGNFLQLTDDPLYFDAYLQS
                     LQVAAISTICCLLIGYPLAWAVAHSKPSTRNILLLLVILPSWTSFLIRVYAWMGILKN
                     NGVLNNFLLWLGVIDQPLTILHTNLAVYIGIVYAYVPFMVLPIYTALIRIDYSLVEAA
                     LDLGARPLKTFFTVIVPLTKGGIIAGSMLVFIPAVGEFVIPELLGGPDSIMIGRVLWQ
                     EFFNNRDWPVASAVAIIMLLLLIVPIMWFHKHQQKSVGEHG"
     gene            complement(9144..10277)
                     /gene="potG"
                     /locus_tag="IRB70_002243"
     CDS             complement(9144..10277)
                     /gene="potG"
                     /locus_tag="IRB70_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000996010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine ABC transporter ATP-binding subunit
                     PotG"
                     /protein_id="HBC0632153.1"
                     /translation="MNDAIPRPQAKTRKALTPLLEIRNLTKSYDGQHAVDDVSLTIYK
                     GEIFALLGASGCGKSTLLRMLAGFEQPSAGQIMLDGVDLSQVPPYLRPINMMFQSYAL
                     FPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVAL
                     ARSLAKRPKLLLLDEPMGALDKKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAG
                     RIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGSVNVFEGVLKERQEDGLVLYSPGLV
                     HPLKVDADASVVDNVPVHVALRPEKIMLCEEPPANGCNFAVGEVIHIAYLGDLSVYHV
                     RLKSGQMISAQLQNAHRHRKGLPTWGDEVRLCWEVDSCVVLTV"
     gene            complement(10372..11484)
                     /gene="potF"
                     /locus_tag="IRB70_002244"
     CDS             complement(10372..11484)
                     /gene="potF"
                     /locus_tag="IRB70_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine/putrescine ABC transporter
                     substrate-binding protein PotF"
                     /protein_id="HBC0632154.1"
                     /translation="MTALNKKWLSGLVAGALMAVSVGTLAAEQKTLHIYNWSDYIAPD
                     TVANFEKETGIKVVYDVFDSNEVLEGKLMAGSTGFDLVVPSASFLERQLTAGVFQPLD
                     KSKLPEWKNLDPELLKLVAKHDPDNKFAMPYMWATTGIGYNVDKVKAVLGENAPVDSW
                     DLILKPENLEKLKSCGVSFLDAPEEVFATVLNYLGKDPNSTKADDYTGPATDLLLKLR
                     PNIRYFHSSQYINDLANGDICVAIGWAGDVWQASNRAKEAKNGVNVSFSIPKEGAMAF
                     FDVFAMPADAKNKDEAYQFLNYLLRPDVVAHISDHVFYANANKEATPLVSAEVRDNPG
                     IYPPADVRAKLFTLKVQDPKIDRVRTRAWTKVKSGK"
     gene            complement(11835..12311)
                     /locus_tag="IRB70_002245"
     CDS             complement(11835..12311)
                     /locus_tag="IRB70_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjN domain-containing protein"
                     /protein_id="HBC0632155.1"
                     /translation="MTSLVVPGLDTLRQWLDDLGMSFFECDNCQALHLPHMQNFDGVF
                     DAKIDLIDNTILFSAMAEVRPSAVLPLAADLSAINASSLTVKAFLDMQDDNLPKLVVC
                     QSLSVMQGVTYEQFAWFVRQSEEQISMVILEANAHQLLLPTDDEGQNNVTENYFLH"
     gene            complement(12399..13301)
                     /gene="rimK"
                     /locus_tag="IRB70_002246"
     CDS             complement(12399..13301)
                     /gene="rimK"
                     /locus_tag="IRB70_002246"
                     /EC_number="6.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6--L-glutamate ligase"
                     /protein_id="HBC0632156.1"
                     /translation="MKIAILSRDGTLYSCKRLREAAIQRGHLVEILDPLSCYMNINPA
                     ASSIHYKGRKLPHFDAVIPRIGTAITFYGTAALRQFEMLGSYPLNESVAIARARDKLR
                     SMQLLARQGIDLPVTGIAHSPDDTSDLIDMVGGAPLVVKLVEGTQGIGVVLAETRQAA
                     ESVIDAFRGLNAHILVQEYIKEAQGCDIRCLVVGDEVVAAIERRAKEGDFRSNLHRGG
                     AASVASITPQEREIAIKAARTMALDVAGVDILRANRGPLVMEVNASPGLEGIEKTTGI
                     DIAGKMIRWIERHATTEYCLKTGG"
     gene            complement(13362..14084)
                     /gene="nfsA"
                     /locus_tag="IRB70_002247"
     CDS             complement(13362..14084)
                     /gene="nfsA"
                     /locus_tag="IRB70_002247"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase NfsA"
                     /protein_id="HBC0632157.1"
                     /translation="MTPTIELICGHRSIRHFTDEPISEAQREAIINSARATSSSSFLQ
                     CSSIIRITDKALREELVTLTGGQKHVAQAAEFWVFCADFNRHLQICPDAQLGLAEQLL
                     LGVVDTAMMAQNALTAAESLGLGRVYIGGLRNNIEAVTELLKLPRHVLPLFGLCLGWP
                     ADNPDLKPRLPASILVHENSYQPLDKDALAQYDEQLAEYYLTRGSNNRRDTWSDHIRR
                     TIIKESRPFILDYLHKQGWATR"
     gene            complement(14068..14355)
                     /locus_tag="IRB70_002248"
     CDS             complement(14068..14355)
                     /locus_tag="IRB70_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1418 family protein"
                     /protein_id="HBC0632158.1"
                     /translation="MRAIGKLPKSVLILEFIGMMLLAVALLSVSGSLSLPEPFSRPEV
                     QILMIFLGVLLMLPAAVVVILQVAKRLAPQLMNRPTQYSRSEREKDNDANH"
     gene            14515..14772
                     /gene="grxA"
                     /locus_tag="IRB70_002249"
     CDS             14515..14772
                     /gene="grxA"
                     /locus_tag="IRB70_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 1"
                     /protein_id="HBC0632159.1"
                     /translation="MQTVIFGRPGCPYCVRAKDLAEKLSNERDDFQYQYVDIRAEGIT
                     KEDLQQKAGKPVETVPQIFVDQQHIGGYTDFAAWVKENLDA"
     gene            complement(14802..15179)
                     /locus_tag="IRB70_002250"
     CDS             complement(14802..15179)
                     /locus_tag="IRB70_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YbjM"
                     /protein_id="HBC0632160.1"
                     /translation="MKHKQRWAGAICCFVLFIVVCLFLATHMKGAFRAAGHPEIGLLF
                     FILPGAVASFFSQRREVLKPLFGAMLAAPCSMLIMRLFFSPTRSFWQELAWLLSAVFW
                     CALGALCFLFISSLFKPQHRKNQ"
     gene            15449..17134
                     /locus_tag="IRB70_002251"
     CDS             15449..17134
                     /locus_tag="IRB70_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate:alanine antiporter"
                     /protein_id="HBC0632161.1"
                     /translation="MNINVAELLNGNYILLLFVVLALGLCLGKLRLGSIQLGNSIGVL
                     VVSLLLGQQHFSINTDALNLGFMLFIFCVGVEAGPNFFSIFFRDGKNYLMLALVMVGS
                     ALVIALGLGKLFGWDIGLTAGMLAGSMTSTPVLVGAGDTLRHSGMESRQLSLALDNLS
                     LGYALTYLIGLVSLIVGARYLPKLQHQDLQTSAQQIARERGLDTDANRKVYLPVIRAY
                     RVGPELVAWTDGKNLRELGIYRQTGCYIERIRRNGILANPDGDAVLQMGDEIALVGYP
                     DAHARLDPSFRNGKEVFDRDLLDMRIVTEEVVVKNHNAVGKRLAQLKLTDHGCFLNRV
                     IRSQIEMPIDDNVVLNKGDVLQVSGDARRVKTIADRIGFISIHSQVTDLLAFCAFFVI
                     GLMIGMITFQFSTFSFGMGNAAGLLFAGIMLGFMRANHPTFGYIPQGALSMVKEFGLM
                     VFMAGVGLSAGSGINNGLGAIGGQMLIAGLIVSLVPVVICFLFGAYVLRMNRALLFGA
                     MMGARTCAPAMEIISDTARSNIPALGYAGTYAIANVLLTLAGTIIVMVWPGLG"
     gene            complement(17370..17588)
                     /locus_tag="IRB70_002252"
     CDS             complement(17370..17588)
                     /locus_tag="IRB70_002252"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001504085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ogr/Delta-like zinc finger family protein"
                     /protein_id="HBC0632162.1"
                     /translation="MMICPLCGSAAHTRSSFQVSSLTKERYNQCQNINCSHTFVTHET
                     FVRSIATPKESNPVQPHPMKSGQVALSL"
     gene            complement(17679..18779)
                     /locus_tag="IRB70_002253"
     CDS             complement(17679..18779)
                     /locus_tag="IRB70_002253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HBC0632163.1"
                     /translation="MNFSSELLNKGNKTPAFSISIEGRDITTVLDNRLMSLTLTDNRG
                     FEADQLDLELDDADGKIVLPRRGAVITLALGWKGQPLFPKGAFTVDEIEHTGAPDRLT
                     IRARSADFRETLNTRREKSWHKTTVGEVVKEIAARHKLKMALGKDLSDKPVVHIDQTN
                     ESDGSFLMRLARQYGAIASVKNGNLLFVRQGQGKSASGKPLPVITITRKDGDSHRFTL
                     ADRGAYTGVIASWLHTREPAKKESTTVKRKRRTAKQKKEPEAKQGDYLVGTDENVLVL
                     NRTYANRSNAERAAKMQWERLQRGVASFSLQLAEGRADLYTEMPVKVSGFKQPIDDAE
                     WSITTLTHTVSPDNGFTTSLELEVRIDDFEME"
     gene            complement(18776..19261)
                     /locus_tag="IRB70_002254"
     CDS             complement(18776..19261)
                     /locus_tag="IRB70_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0632164.1"
                     /translation="MMMVLGLYVFMLRTVPYQELQYQRSWRHAANSRVNRRPSTQFLG
                     PDNDMLTLSGVLMPEITGGRLSLLALEQMAEQGKAWPLIEGSGTIYGMYVIEGLNLTE
                     TEFFRDGMPRRIEFSLSLKRVDESLSDMFGDLSTQLNNLQDTATSALSDISKTVGGLL
                     S"
     gene            complement(19258..22335)
                     /locus_tag="IRB70_002255"
     CDS             complement(19258..22335)
                     /locus_tag="IRB70_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001282780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBC0632165.1"
                     /translation="MSDNNLRLQVILNAVDKLTRPFRAAQASSKELAGAIQNTRNSLK
                     ELNKQAGRIDEFRKTRSQLAITANNLNAAREEAAKLATQFAATNRPTAAQAKLFSQAK
                     TRVQELQQTYNGLLGAVQRQRQALKESGIDTRQLSSAQRELKKNAEETRQALEGQQKA
                     LKRLGEQQARMNAAREQYSRRLEVRDRIAGAGATTTAAGLAMGAPVMAAVKSYTSMED
                     AMKGVAKQVNGLRDDNGNRTARFYEMQDAIKAASEQLPMENGAVDFAALVEGGARMNV
                     ANPDDSWEDQKRDLLAFASTAAKAATAFELPADELSESLGKIAQLYKIPTRNIEQLGD
                     ALNYLDDNAMSKGADIIDVMQRLGGVADRLDYRKAAALGSTFLTLGAAPEVAASAANA
                     MVRELSIATMQSKSFFEGMNLLKLNPEVIEKQMTKDAMGTIQRVLEKVNALPQDKRLS
                     AMTMLFGKEFGDDAAKLANNLPELQRQLKLTAGNDALGSMQKESDINKDSLSAQWLLV
                     KTGAQNTFSSLGETLRQPLMDILYTVKSITGALRRWVEANPELTGTLMKVAAVVAAVT
                     VGLGTLAVALAAVLGPLAVIRLGFSVLGIKTLPSVTAAVTRTSSALSWLAGAPLALLR
                     RGLASSGNAAGLLTAPLSSLRRTASLTGNVLKTVAGVPVALLRSGLSGLRAVAMMFMN
                     PLAALRGGLAAAGAVLRVLASGPLAMLRVALYAISGLLGALLSPIGLVVTALAGVALV
                     VWKYWQPITAFLAGVVEGFKAAAGPISAAFEPLKPVFQWIGDKVQALWGWFTDLLTPV
                     KSTSAELQSAAAMGRRFGEALAEGLNMVMHPLDSLKSGVSWLLEKLGIVSKEAAKAKL
                     PESVTRQQPATVNADGKVMMPSGGFPSWGYGFAGMYDSGGYIPRGQFGIVGENGPEIV
                     NGPANVTSRRNTAALAAVVAGMMGVAAAPAELPPLHPLALPAKGGEAIVSRAATVPPV
                     YRIEAPTQIIIQTQPGQSAQDIAREVARQLDERERRLKAKARSNYSDQGGYDA"
     gene            complement(22328..22447)
                     /locus_tag="IRB70_002256"
     CDS             complement(22328..22447)
                     /locus_tag="IRB70_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HBC0632166.1"
                     /translation="MADIATIFHWPPSVTDVMPLTEVLEWRYKAIQRSGANDE"
     gene            complement(22462..22764)
                     /locus_tag="IRB70_002257"
     CDS             complement(22462..22764)
                     /locus_tag="IRB70_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HBC0632167.1"
                     /translation="MSDKQTEKTIQLDTPIKRGKTEITEIVLRKPQSGALRGTRLQAI
                     MDMDVNAMMTVIPRISSPALTAQEIAEMDPADLTAMSVEVVTFLLKKSVLAGLPIA"
     gene            complement(22819..23334)
                     /locus_tag="IRB70_002258"
     CDS             complement(22819..23334)
                     /locus_tag="IRB70_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HBC0632168.1"
                     /translation="MALPRKLKHLNLFNDGNNWQGIVESLTLPKFTRKYEKYRGGGMP
                     GAVDVDLGLDDSALDTEFSIGGTELLLFKQMGKATVDGIQLRFTGSIQRDDTGEVQAV
                     ELVVRGRHKEVDSGEWKTGESNTTKVTSTNSYAKLTINGEVLYEVDLINMVEIVDGVD
                     LMEAHRNALGL"
     gene            complement(23344..24516)
                     /locus_tag="IRB70_002259"
     CDS             complement(23344..24516)
                     /locus_tag="IRB70_002259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath protein"
                     /protein_id="HBC0632169.1"
                     /translation="MAQDYHHGVRVVEVNEGTRSITTVSTAIVGMVCTGDDADAKMFP
                     LNKPVLITDVLTASGKAGESGTLARSLDAIADQAKPVTVVVRVPQGETEEETTTNIIG
                     AVTAEGKKTGMKALLSAQTQLGVKPRILGVPGHDNKAVATELLSVAQSLRGFAYLSAY
                     GCKTVQEAITYRENFSQREGMLIWPDFTGWDTVLNAEATAYATARALGLRAKIDEQTG
                     WHKSLSNVGVNGVTGISADVFWDLQDPATDAGLLNQNDVTTLVRKDGFRFWGSRCLSD
                     DPLFAFENYTRTAQVLTDTMAEAHMWAVDKPLNPSLARDIIEGIRAKMRSLVSQGYLI
                     GGDCWLDESVNDKDTLKAGKLTIDYDYTPVPPLENLMLRQRITDQYLVNFASQVSA"
     gene            complement(24650..25252)
                     /locus_tag="IRB70_002260"
     CDS             complement(24650..25252)
                     /locus_tag="IRB70_002260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBC0632170.1"
                     /translation="MGGAVLNDALIAVKAGDITVYNYDNGTQEYISTSTEYLAVGVGI
                     PACSCLDAPGTHKTGYAICRSTDLNSWKYVPDHRGEIVYSTETGEPKEITAPGDYPEN
                     MTTIAPLTPYDKWDGEKWVTDTEAQYGAAIEAAEAQRQSLIDTAMASISLIQLKLQAG
                     RKLTQTENTRLNAVLDYIDAVMATDTSTVPDIYWPELPQF"
     gene            complement(25252..26793)
                     /locus_tag="IRB70_002261"
     CDS             complement(25252..26793)
                     /locus_tag="IRB70_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001498270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0632171.1"
                     /translation="MSTKFYTLLTDIGAAKLASAAALGVPLKITHMAVGDGGGVLPTP
                     DAKQTALVNEKRRAALNMLYIDPQNSSQIIAEQVIPENEGGWWIREVGLFDESGALIA
                     VGNCPESYKPRLAEGSGRTQTVRMVLITSSTDNITLKIDPAVVLATRKYVDDKALELK
                     VYVDDLMAKHLAALDPHSQYAPKASPTFTGTPKAPTPAAGNNTTQLATTAFVQAALKA
                     LINGAPATLDTLKEIAAAINNDPKFSTTINNALELKASLSSPALTGTPTAPTAAQSVN
                     NTQIATTAFVKSAIAAMVGSAPAALDTLNELAAALGNDPNFATTMLNALSGKQPLDNT
                     LTNLSGKDVAGLLAYLGLGEGSALPVGVPVPWPSATPPTGWLKCNGAAFSAVEYPKLA
                     KAYPTNKLPDLRGEFIRGWDDGRGVDSGRSLLSAQNSLSFDHRHFLPTAYGSGGDGLM
                     SAVFKDDNSAMSYYPAGTNEYNANPSSGTILQTYSARNTDGSDKFGNESRPRNISFNY
                     IVRAA"
     gene            complement(26790..27395)
                     /locus_tag="IRB70_002262"
     CDS             complement(26790..27395)
                     /locus_tag="IRB70_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HBC0632172.1"
                     /translation="MNSLLPPGSTPLERRLAQTCSGISDLQVPLRDLWNPATCPVSFL
                     PYLAWAFSVDRWDEGWTESVKRQVVKDAFYIHQHKGTTSAVRRVVEPFGFLNRIIEWW
                     QTGETPGTFRLDIGVQDQGITEDTYLELERLISDAKPCSRHMIGMSINLQTSGPHWVG
                     AASYLGEEITIYPYINETIISGGTAHEGGAVHVIDTMRVNP"
     gene            complement(27388..28296)
                     /locus_tag="IRB70_002263"
     CDS             complement(27388..28296)
                     /locus_tag="IRB70_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate assembly protein"
                     /protein_id="HBC0632173.1"
                     /translation="MAVIDLSQLSAPQIVDVPDFETLLAERKAEFVALHPKDEQEAVI
                     RTLELESEPVTKLLQENAYRELLLRQRINEAAQAVMVAYAMGGDLDQLAANYNVKRLT
                     VTPADNDAVPPVAAVMESDEALRLRVPAAFEGLSVAGPTAAYEFHARSADGRVADASA
                     TSPAPAEVVLTVLSREGDGTAEKDLLDVVEKALNSENVRPVADRLTVRSAEIIPYRVE
                     ATIFLYPGPEAEPVMAAAKASLQKYIASQTRLGRDIRRSAIFAALHVEGVQRVELASP
                     LADVVLNKTQAASCTQWSVTNGGTDE"
     gene            complement(28283..28642)
                     /locus_tag="IRB70_002264"
     CDS             complement(28283..28642)
                     /locus_tag="IRB70_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013098787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HBC0632174.1"
                     /translation="MTLYSGMNNTSGKVITDIDHLRQSVRDILLTPQGSRIARREYGS
                     LLSVLIDQPQNPALRLQVMSAVYVALSRWEPRLTLDSITINSNFDGSMVVELTGRRNN
                     GVPVSLSVSTGAENGSD"
     gene            complement(28639..29217)
                     /locus_tag="IRB70_002265"
     CDS             complement(28639..29217)
                     /locus_tag="IRB70_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001552634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HBC0632175.1"
                     /translation="MNAQLTEIMRLITNLIRTGVVTEVDRENWLCRVKTGDLETNWIS
                     WLTLRAGNARTWWRPSEGEQVVLLSLGGNLETAFALPAVYSNQFAPPSTSADACVTEH
                     PDGGWFEYEPATGRWYVRGIKSMVIEAADNITMKTSEFVLEADRTRINSEVVINGGVT
                     QGGGAMSSNGIVVDAHQHTGVLKGGDTTGGPV"
     gene            29321..30127
                     /locus_tag="IRB70_002266"
     CDS             29321..30127
                     /locus_tag="IRB70_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001573379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632176.1"
                     /translation="MSVMNPISSNIFNAEFLNTPAAALAAWISIIGAVITLVTIVIRA
                     LFKYRKSHDVILKKSGIPAFILNFFLIKISLKRLPTITWAEKSFTVLFSLLFLCAIYL
                     FGPVFIQAIRTPPNSTLLYWIKSGESFYMSKKMATAATILTTPDWEISKDDCEESSSA
                     STEKYKSLTIEHKEILCKLLTTDEGNAYIDEEVKNFVKDKFFIYSFAPTTIFILLWIS
                     LGFILTIHYSKKVRKYILTEQKNAIHWAYGEFKTEGIYSIYQELEHKTHH"
     gene            complement(30069..30515)
                     /locus_tag="IRB70_002267"
     CDS             complement(30069..30515)
                     /locus_tag="IRB70_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000829154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage virion morphogenesis protein"
                     /protein_id="HBC0632177.1"
                     /translation="MAELQKVDDWLSALLANLEPAARSRMMRQLAQELRRTQQQNIRM
                     QRNPDGSSYEPRRVTARSKKGRIKRQMFAKLRTTKYLKTAASADSASVQFEGKVQRIA
                     RVHHYGLRDRVSRKGPEVRYAERRLLGLNGESYVLTLDILNRFLLS"
     gene            complement(30508..30939)
                     /locus_tag="IRB70_002268"
     CDS             complement(30508..30939)
                     /locus_tag="IRB70_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0632178.1"
                     /translation="MNKPQSLRHALNKAVPYVRNNPDKLHLFVDNGSLVATGASSMSW
                     EYRYTLNVVIEDFSGDQNLLMAPVLLWLRDNQPDAINNPALREKLFTFEVDILRNDVC
                     DISLNLQLTERVLVSTDGTVSSVEAVAEPDEPEEMWTVKRG"
     gene            complement(31035..31463)
                     /locus_tag="IRB70_002269"
     CDS             complement(31035..31463)
                     /locus_tag="IRB70_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysB family phage lysis regulatory protein"
                     /protein_id="HBC0632179.1"
                     /translation="MNRLLLVVLALLLAALGWKTWRLADASQTISTQADELRSKSQAL
                     AKSNSQLISLSILTETNNREQARLYADAEQTSALLRQRQHRIEELKRENEDLRRWADT
                     PLPADIIRLRERPTLTGGAAYRQWLSASDAVSAGAGSAAH"
     gene            complement(31460..31837)
                     /locus_tag="IRB70_002270"
     CDS             complement(31460..31837)
                     /locus_tag="IRB70_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000730949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632180.1"
                     /translation="MKKKLISGLFLMLWIALLIAAMVYPQGIFPVLAASGVWVACLLT
                     WGAIPVALAALIKNGPLWQELRASLLKTITRKENVFISWMMRLLIVVSLAWTGWAITL
                     VFYLLTVIAFWITRNQMAQQVAA"
     gene            complement(31839..32351)
                     /locus_tag="IRB70_002271"
     CDS             complement(31839..32351)
                     /locus_tag="IRB70_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001069913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HBC0632181.1"
                     /translation="MNPSIVKRCLVGTVLAIAATLPGFQQLHTSVEGLKLIADYEGCR
                     LQPYQCSAGVWTDGIGNTSGVIPGKTITERQAAEGLISNVLRVERALERCMKQQPPQK
                     VYDAAVSFAFNVGTGNACSSTLVKLLNQRRWADACRQLPRWVYVKGVFNQGLDNRRAR
                     EMAWCLQGAN"
     gene            complement(32332..32547)
                     /locus_tag="IRB70_002272"
     CDS             complement(32332..32547)
                     /locus_tag="IRB70_002272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632182.1"
                     /translation="MTLERISAFITYCIAVVLAWLGDLSIKDASTLGGLMIGVLMLAI
                     NWYYKHKAYQLLRDGQISREDYESINR"
     gene            complement(32551..32754)
                     /locus_tag="IRB70_002273"
     CDS             complement(32551..32754)
                     /locus_tag="IRB70_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HBC0632183.1"
                     /translation="MKVRAHQYDTVDALCWRHYGRTQGVTEQVLKANPGLAEYGPFLP
                     HGLQVELPDIPTTTTVQTVQLWD"
     gene            complement(32754..33218)
                     /locus_tag="IRB70_002274"
     CDS             complement(32754..33218)
                     /locus_tag="IRB70_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head completion/stabilization protein"
                     /protein_id="HBC0632184.1"
                     /translation="MKFVAPEQAPEQAEIIRNTPFWPDVDLSEFRSVMRTDGTVTQPR
                     LKQVALSAISEVNAELYEFRRRQQMLGYASLAEVPAEQLDGKSERIQHYFNAVYCWAR
                     AMLNERYQDYDATASGVKRGEELAEASGDLWRDARWAISRVQDAPHCTVELI"
     gene            complement(33314..33964)
                     /locus_tag="IRB70_002275"
     CDS             complement(33314..33964)
                     /locus_tag="IRB70_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase endonuclease subunit"
                     /protein_id="HBC0632185.1"
                     /translation="MSLSPARQHRLRVQAEQAAREGGSVRHASGYDLMLLQLAEDRRR
                     LKGVQSTVKKAEIKVELLPKYAAWAEGVLAAGGAQQDDVLMYVMLWRIDAGDYAGALE
                     IGRHALRHGWVMPLGNRNVQTVLAEEMADAAQSAMLAATGFDAALLLQTLELTDGLDM
                     PDQSRARLHKAIGAVLSESNPASALNHLNHALQLDPRCGVKKDKQQLERRLRNDSR"
     gene            complement(33968..35026)
                     /locus_tag="IRB70_002276"
     CDS             complement(33968..35026)
                     /locus_tag="IRB70_002276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein, P2 family"
                     /protein_id="HBC0632186.1"
                     /translation="MKKNTRFAFNAYLQQLARLNGVAVEELSSKFTVEPSVQQTLEDQ
                     IQQSAAFLTLINVTPVTEQSGQLLGLGVGSTIAGTTDTTAKEREPVDPTLMVDVEYKC
                     EQTNFDTVLTYAKLDLWAKFQDFQVRIRDAIVKRQALDRIMIGFNGVKRAKTSNRSEN
                     PLLQDVNKGWLQKIREDAPDHVMGSSTTGGETTPGAVKVGKGGEYANLDAVVMDAVNE
                     LIDVVYQDDDDLVVICGRELLSDKYFPLVNKEQENSEKLAADMIISQKRMGGLQAVRA
                     PFFPPNALLITRLDNLSIYWQEDTRRRSVIDNPKRDRIENFESVNEAYVVEDYRCAAL
                     VENIQIGDFSAAAAETGA"
     gene            complement(35043..35876)
                     /locus_tag="IRB70_002277"
     CDS             complement(35043..35876)
                     /locus_tag="IRB70_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPO family capsid scaffolding protein"
                     /protein_id="HBC0632187.1"
                     /translation="MTVKAKRFRIGVEGATTDGREIQREWLEQMAASYNPAVYTALIN
                     LEHIKSYLPDSTFNRYGKVTALFAEEITEGPLAGKMALYADVEPTESLVELVKKGQKL
                     FTSMEVSPKFADTGKAYLVGLAATDDPASLGTEMLTFSASAAHNPLANRKQNPANLFT
                     AAEETVIELEEIQDDKPSLFARVTALFTKKEQSDDARFSDVHKAVELVATEQQNLSAR
                     TEKSLSEQEERLSELETALQAQQTAFNELVDKLSQEDSRQDYRQRATGGNAPADTLTN
                     C"
     gene            36019..37785
                     /locus_tag="IRB70_002278"
     CDS             36019..37785
                     /locus_tag="IRB70_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase ATPase subunit family protein"
                     /protein_id="HBC0632188.1"
                     /translation="MNTTLTPADLDPRRQAMLLYFQGYRVARIAEMLGEKVATVHSWK
                     KRDKWGDYGPLDQMQLTTAARYCQLIMKEHKEGKDFKEIDLLARQSERHARIGKFNNG
                     GNEADLNPNVANRNKGPRRQPEKNVFTDEQIEKLVEIFHSSMFNYQRHWWEAGKTNRI
                     RNLLKSRQIGATFYFAREALIDALLTGRNQIFLSASKAQAHVFKQYIIDFAKEVEVEL
                     KGDPMVLPNGATLYFLGTNARTAQSYHGNLYLDEYFWIPKFQELRKVASGMAIHKKWR
                     QTYFSTPSSLTHSAYPFWSGALFNRGRNKADKVDIDLSHSNLAPGLLCADGQYRQIVT
                     VEDAVRGGCNLFDLDQLRMEYSPDEYQNLLMCEFVDDLASVFPLSELQACMVDSWEVW
                     TDFHALALRPFGWREVWIGYDPAKGTQNGDSAGCVVVAPPAVPGGKFRILERHQWRGM
                     DFRAQADAIKKLTEQYNVTYIGIDSTGVGHGVYENVKAFFPAVREFVYNPNVKNALVL
                     KAYDIISHRRLEFDAGHTDIAQSFMAIRRATTASGNRPTYEASRSEEASHADLAWATM
                     HALFNEPLQGESANTSNIVEIF"
     gene            37785..38819
                     /locus_tag="IRB70_002279"
     CDS             37785..38819
                     /locus_tag="IRB70_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000520395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBC0632189.1"
                     /translation="MGKSKKNRAAATNQIQHKNQTSAEAFSFGDPVPVLDRRELLDYV
                     ECVQTDRWYEPPVSFDGLARTFRAAVHHSSPIAVKCNILTSTYIPHPLLSQQAFSRFV
                     QDYLVFGNAYLEKRTNRFGEVIALEPALAKYTRRGLDLDTYWFVQYGMTTQQYQFTKG
                     SIFHLMEPDINQEIYGLPGYLSAIPSALLNESATLFRRKYYINGSHAGFIMYMTDAAQ
                     NQEDVNNLRNAMKSAKGPGNFRNLFMYSPNGKKDGLQIIPLSEVAAKDEFLNIKNVSR
                     DDMMAAHRVPPQMMGIMPNNVGGFGDVEKAAKVFVMNELLPIQKHILQLNEWAKKNII
                     SFSEYSVECM"
     gene            complement(38856..>39020)
                     /locus_tag="IRB70_002280"
     CDS             complement(38856..>39020)
                     /locus_tag="IRB70_002280"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632190.1"
                     /translation="KNYELHKKIESYKKSDLKLVTEFVSESEAREHKWDDSLIKERTD
                     GLALETFAKI"
BASE COUNT         9178 a        10723 c         9621 g         9498 t
ORIGIN      
        1 atttttgtct ttcaagtttc ccattcgata cattacgtat tccaatggta attctttcat
       61 tacccacttt tatttcaact tcgttatctt ctgatttacc aagatatttt ttaacatcaa
      121 tctcgaaagc attactaaaa aatatattaa attgataatt cgctgatgga atattttccg
      181 ctagcaactc atcatttttt atgagatcac tatcagcatt tattgctaat atcagatgca
      241 agtagatggt gtcccatgta gacaactcac ccttacgact ggaatttaat atcgcgaaaa
      301 actccctcag tgaatcgagg aaattatcac tttgattcag ttgtgtgcct ggaaatgatg
      361 atacttgatc agatatattg tttatcatat ttaaaatcac ccaagggaaa agatattcta
      421 ctgaattcct tgtgctttat tattataaaa gcacaacgca tttatactca tattaattaa
      481 cgaaacactg atacagtttg atttattctt cgctcaaact cattagctta aattctttac
      541 ccacaactgt agcatatata atattatcaa aagtcaaagc tgggactatc aaatttcgct
      601 cattttcaaa aatacaatgt aattttagca atcatcttaa tcgcaggatc tcttattgca
      661 tgtgaaaaat tctgtaatga ttagacaata accgcgttca tttatcacgc gttataaatg
      721 tgaaactggc ttcttgcaga tgctcttaac ctctacagga ggatttatcc cgccatttca
      781 gaactatcat atttacctta aatgatcatt tcagccatat aacacgctca acctcacaaa
      841 tggtttacac tgtctattgt ttgggtaatt taagttagtc agctacgagc aaccttgagt
      901 gggtagccag caatggactc aaacccaatc aggtgttcag attgtttcag aattgtatta
      961 aaaacaatgt attaaataat ctgataacgt ttggtcgtag tgtgacgcag acagcaagct
     1021 aataaggaaa tgattatgcg ctaccgttca ctatctctac ttattccatg tgcactgctg
     1081 ctgagtgcct gtaccaccgt cacgccagct tataaagata acggcccccg caccggttcc
     1141 tgtgtccagg gtggccctga cagcgtggct caacaattct atgactaccg cattcaacat
     1201 cgtagcaatg acattaccgc cctgcgcccc tatttgagtg acaaactggc aaccctactt
     1261 agcgatgcca gccgcgataa tagtcatcgt gaattgttaa gcagcgatcc gttctccagt
     1321 cgaaccacct tgccagacag cgcccacgtt gccagtgcat cgactatccc taatcgtgat
     1381 gcccgtaaca ttccattgcg cgtggatctc aaacagggtg accagggctg gcaggatgaa
     1441 gtgttaatga ttcaggaagg ccagtgttgg gtcatcgacg atgtgcgcta cttaggcggt
     1501 agcgttcatg ccacagcggg tacgctccgt cagtccatcg agaatcgcta acgccttgat
     1561 caaccaataa accccgtaaa ttgtccggca tttcgtgagg aatgccgaca tttatgctcg
     1621 ccgaccaccg cccccgttat tttgtgctat gtttattgaa taatgcgctt tgcttttaac
     1681 ttttaaagca gaaatattgc ataattattc tgtcaaaggt actatcttcg acctcaatag
     1741 ctatcagact gccagtatac gagtgtcaat gagtattcaa ttaaacggca ttaattgctt
     1801 ctacggcgcg catcaggcgc tgttcgatat cacgctggat tgcccacagg gcgaaacgct
     1861 ggtgttactt ggccccagcg gcgcggggaa aagctcgctg ctgcgtgtac tcaatctgct
     1921 tgagatgccg cgctccggta cgctcaacat tgcaggcaac catttcgatt tcaccaaaac
     1981 accctctgac aaagcgattc gcgatttgcg tcgtaacgtt ggcatggtgt ttcagcaata
     2041 caacctgtgg ccgcatctga ccgtgcagca aaacctgatt gaagcgccct gccgtgtact
     2101 ggggttgagc aaagatcagg cgctggcccg tgcagaaaaa ctgctggaac gtctgcgtct
     2161 caaaccttat agcgatcgtt acccgctgca tctttctggt ggtcagcagc agcgtgttgc
     2221 tattgcccgt gcgttgatga tggaaccgca ggtactgctg ttcgatgaac cgaccgccgc
     2281 actggacccg gaaattacgg cacaaatcgt cagcatcatt cgtgagttgg cagaaacgaa
     2341 tattacccag gtgatcgtca cccacgaagt tgaagtggcg cgtaaaaccg ccagccgagt
     2401 ggtgtatatg gaaaacggtc atatcgtaga acaaggcgac gcgagctgct ttaccgagcc
     2461 gcaaaccgaa gcatttaaaa actatctctc tcactaatat tcgggataac aacaatgaaa
     2521 aaagttctga ttgccgcgtt aattgcaggt tttagtcttt ccgccacagc tgccgaaact
     2581 attcgttttg ctaccgaagc ctcctatcct ccgtttgaat cgattgatgc aaacaaccag
     2641 atcgttggtt ttgacgtcga cctggcacaa gcgctgtgta aagagattga tgcaacctgc
     2701 actttctcca accaggcatt tgacagcctg atcccaagcc tgaaattccg tcgcgtggaa
     2761 gcggtgatgg ccgggatgga tatcacccca gaacgtgaaa agcaggtgct gtttaccacc
     2821 ccttactatg acaactctgc cctgtttgtg ggtcagcagg gtaaatacac cagtgttgat
     2881 cagctgaaag gcaaaaaagt cggcgttcag aacgggacga cacaccagaa gttcattatg
     2941 gataagcacc cggaaatcac caccgttccg tatgacagct accagaacgc aaaactggat
     3001 ctgcaaaacg gtcgtatcga cagcgtattc ggtgacaccg cagtggtcac cgagtggctg
     3061 aaagacaacc cgaaactggc ggcagtgggc gataaagtga ccgataaaga ttacttcggt
     3121 actggtctcg gcatcgcggt acgtcagggc aacactgaac tgcagcagaa actcaacact
     3181 gcgctggaaa aagtgaagaa agatggcact tacgaaacca tctacaacaa atggttccag
     3241 aagtaattcc tgatgaatga attttttcct ttagcaagcg ccgccgggat gaccgtcggc
     3301 cttgccgttt gtgcattgat tgtcgggctg gcgctggcga tgttctttgc ggtatgggag
     3361 tctgcaaaat ggcgtcccgt cgcgtgggca ggttcagcgt tggtgacggt tctgcgcggc
     3421 ctgccagaaa ttctggtggt gctgtttatc tattttggct cctcgcagct gctgctgacg
     3481 ctttcggatg gcttcactat caatcttggg ttcgtgcaga tcccggtgca gatggacatt
     3541 gagaacttcg acgttagccc gttcctttgt ggtgtcatcg ctctgtcgct gctgtatgcc
     3601 gcctatgcct cgcaaacgct gcgcggcgcg ttgaaagcgg tgccggtggg ccagtgggaa
     3661 tccggacagg cgctggggct gtcgaaatcg gctatctttt tccgtctggt gatgccgcag
     3721 atgtggcgtc atgcgctgcc tggtctcggt aaccagtggc tggtgctgct gaaagatacc
     3781 gcgctggtca gtttgataag cgtgaatgat ttaatgctac aaaccaaaag catcgctacc
     3841 cgtacccagg aaccgtttac ctggtacatt gtggcggcgg cgatttacct ggtgatcacc
     3901 ctgctcagtc agtacattct caaacgcatt gacctgcgcg cgacacgttt tgagcggagg
     3961 cccagctaat gtttgagtat ttacccgaac tgatgaaagg gctgcacacc agcctgacgc
     4021 taaccgttgc ctcgctgatt gtggcactga ttctggcatt gatttttacc atcatcctga
     4081 cgctgaaaac gccggtgctg gtgtggctgg tgcggggcta tatcacgctg tttaccggta
     4141 cgccgctgct ggtgcagatc ttcctgattt attacggacc gggtcagttc ccgacgttgc
     4201 aggagtatcc ggcactgtgg catctgttgt cagaaccgtg gttatgtgcg ctgattgcgt
     4261 tgtcgctgaa cagtgcagcg tataccacgc agctgtttta cggtgccatt cgcgcgatcc
     4321 cggaaggtca gtggcagtcc tgtagcgccc tgggaatgag caaaaaagat acgctggcga
     4381 tcctgctgcc gtacgcgttt aaacgctcgc tctcttctta ttccaacgaa gtggtgctgg
     4441 tgttcaaaag tacttctctg gcttacacca ttacgctgat ggaagtgatg ggatacagcc
     4501 agttgttgta cggacgcacc tacgatgtca tggtgttcgg tgcggcaggg attatttacc
     4561 tgattgttaa cggtctgctg acgctgatga tgcgtctgat cgagcgtaaa gcactggcgt
     4621 ttgagcgaag gaattaattt ggctgcgtgc tgatgccgga tgcggcgtgg acgccttatc
     4681 cggcctacat agtgcataaa ttcttataat gaagacgggc aactcactaa gctgtccgtc
     4741 tttttttatt tcatttaaat tatttaatca tatttattgc atataaattc acttgatggc
     4801 attgttatcc catgccgcag acacggccaa aaatcataag attgacagac gggagttcca
     4861 tcatgaaaaa gttagttctt gccgctttac ttgcttcttt tactttcggt gcttctgccg
     4921 cagagaaaat caattttggc gtttcagcca cctatccacc ctttgaatct ataggtgcta
     4981 ataatgagat tgtcggcttt gatatcgatc tggcaaaagc cttgtgcaaa caaatgcagg
     5041 cagaatgtac ttttacgaat cacgcgttcg acagcctgat cccgtcactg aaattcagaa
     5101 aatatgacgc cgtaatctcc ggaatggata tcacgccgga gcgtagcaaa caggtatcgt
     5161 ttaccacgcc ctactacgaa aactcagccg tcgtgattgc caaaaaagat acctacaaaa
     5221 cgtttgccga tctgaaaggc aaacgtattg ggatggaaaa cggcaccacg caccagaaat
     5281 atattcagga tcagcacccg gaagtgaaaa ctgtctccta tgacagttat cagaatgcct
     5341 ttatcgatct gaaaaatggc cgtattgatg gcgtatttgg tgacaccgca gtggtaaacg
     5401 aatggctgaa aaccaatccg caactgggcg ttgcgactga aaaagtgacc gatccgcaat
     5461 acttcggcac cggcctaggt atcgctgtac gtccggataa caaagctctg ctggaaaaac
     5521 tgaataatgc gctggcagca attaaagctg acggtacata tcagaaaatc aatgaccagt
     5581 ggttcccaca gtaagattca gaaagccgca cctgcggctt ttttattgct tcaccagcag
     5641 cgtcagcact tcatagtgcg cggtgtgcgg gaacatatca aaaagctgta cccgttcgat
     5701 gcggtaacct ggcagttcgc ggatatcttt cgccatggtt tgggcgttac agctggagta
     5761 gataataaaa cgcggtgcca tcgttgagag ataatcacac agcggtttac caatgccgcg
     5821 gcgcggcggg ttaaccagca ccagctccgg cacctccccc tgagcagtgg caaactgcgt
     5881 ggagtccagc gcctgaaatt gcaaacgcgt taagcccagt tcagcggctg actgctttgc
     5941 acaggcaatg gcctctggcg caatttcgat cccggttaac tgcatgtcag gcgtcgcgca
     6001 gtgtaaacca aagcccccca caccgcagaa cagatcccac atatgtttaa ccggcagctg
     6061 tcgtacccag tcgcgcgcgg tggcgtaaag ctggctggcg accgccggat tagtctggaa
     6121 gaaactttgc ggacggatcc acagcggtac gtcattaaaa cgctctgcca gcgcctgttg
     6181 ttcggtcagg tagatctccg tctccccttc cataatcgcc atatgtaccg gctgaatatt
     6241 gacggtaata actttcagct gcggtaattg ttcctgtaac cacggcagcg ccttacgcag
     6301 ttgcgccagt ttggtatcag aacgcagtac aaaacgcagc atcatgccgc catcgctctg
     6361 gctttcagtc agcagaatgt atttcagttc accacgttta cgcgccacgt tgtaaggtgt
     6421 taaacccgca cgggcgatga agggttttag cgccgcaaaa acgggcgcaa atgaggctgg
     6481 ataaagcggg cagtcacaaa ggtcttccgg tgtaccatct cgatgcagca taccgagcag
     6541 tggtttttca acgctaccac tcaccaccat tttggcttta ttacgaaacc cttgttccgg
     6601 gcctgacacc ggcgcgcacc attcctcaac cggaaagtcg gcgagcagat ttttaagatc
     6661 ggcggtttta gcggagagtt gctctggaat cggctgcgtt atccactgac aggaacgaca
     6721 gcgacccgcg tcgtaaagtg cgcactgcat acattgacct tcacatcatc aggggcgacg
     6781 attatacaca ttattgcaac tggaagaacc gccgactggt cgagggaacg aacagcagca
     6841 tcaggatgag catatccggc agcttctgca gcatcaggct atggaagatt tcacgttttg
     6901 attcaccggg aatgctgaac agctccggat aaccataccc cagcgaagcc gcccacaagt
     6961 aacttgcggc cgtgatttgt gtcaacagat acagccagcg cgcccagcga cgccctttca
     7021 ccagtgaaaa cgcacaccag atctcaatga aaaccagcac cagactgctt aaaaagacca
     7081 gcgttaaact ccaggtttgt acgctgcgat gaatgaactc gccaataccg cgcacgccca
     7141 gcgtattgaa aatcatcagc acgtcgaggc cacggatcat aataatggcg agcgccgcta
     7201 cctgcaccag cgcaggcaca ttcaggcgag catgagatga agatgttttc ttaaaaaatc
     7261 ccaacgtttc gtcttccatg aaaacaatgc cgcgacatgc gcggcattat gtagccaggt
     7321 tggcaaattt tagtgtcttc agccacgtct tgcacgctgg atatcgcgta tccgctgttt
     7381 ttctgcgcgc gccatcagat accaggcgat aaatccgaca attccgaccg caccgaggat
     7441 caatgttgcc agggcgttga tttccggatt cactcccatc cgcacgctag aaaagaccag
     7501 catcggtaac gtggtggctc ccggcccgga aacaaagctg gcgatcacca gatcatcaag
     7561 cgacaaagta aaagccagta accagccaga aatgatcgcg ggcatgatca tcggtagcgt
     7621 aatgacgaaa aacactttca gtggcgtcgc accaagatcc atcgcggctt cttcaatgga
     7681 acggtccagc tcccgcaatc ttgaagaaat aacgaccgcc acataagccg tacagaaagt
     7741 gacatgcgcc agccagatgg tgagcatacc gcggtccgca ggccagccaa tggcatgagc
     7801 aagcgcgacg aatagcaaca atagcgacaa gcccgtgatg acatctggca tcaccagcgg
     7861 cgcggtgatc ataaaggcaa aaccatttga tccgcgaaac ctgccaaagc gcaccagcac
     7921 gaccgccgca atcgtcccga ggatcgccgc cgccgtcgcc gcacaggccg caattgtcag
     7981 gcttaaacca accgcactca tcatcgcgtc atcgcgcaat aattcgccat accagcgcgt
     8041 tgaccagccg gcccacaccg tcaccagctt cgagctgttg aatgaataga tcaccagcat
     8101 cagcattggc gcgtagagaa aggtgaagcc cagcagcaaa atcacaatcc gccagggcga
     8161 acgaactacc ggtaaattat tcatccgtgt tctcccacgc ttttttgctg atgcttgtgg
     8221 aaccacatta tcggcacaat tagcagcagc aacatgatga tcgctaccgc tgaggccacc
     8281 ggccagtcgc ggttgttaaa gaactcctgc cacagcacgc gcccgatcat gatgctgtcc
     8341 gggccaccga gcagttcagg gatcacaaac tcgcccacag ccgggataaa caccagcatc
     8401 gatccggcaa taatcccgcc tttggtcagc ggcacgatca cagtaaagaa cgttttcagc
     8461 ggtcgtgcac cgagatccag tgccgcttcc accagcgaat aatcaatacg aatcaacgcg
     8521 gtataaatcg gcagtaccat aaacggcacg taggcataaa caatgccgat ataaacggcc
     8581 agattggtat gcagaatggt cagcggctgg tcgataaccc ccagccacag cagaaaatta
     8641 ttcagtacgc cgttattttt taatattccc atccaggcat aaacgcgaat cagaaacgag
     8701 gtccacgacg gcaggatcac cagtagcaat aagatattac gggtcgaagg cttactgtgc
     8761 gccaccgccc acgccagcgg atagccgatc agtaaacagc aaatagtcga aatcgccgcc
     8821 acctgtaacg actggagata agcatcgaaa tagagcggat cgtcagtcag ttgcagaaaa
     8881 ttaccgagat taagagtgat ggaaagttgc ccgtcagccc actccatcag ttcggtataa
     8941 ggtggaatag cgcgcgccat ctccgccagg cttattttaa agacaatcag aaatggcagc
     9001 agaaacagca ggattagcca gatatacggc agcgcaatca ccagtttgcg cccatgcttc
     9061 atttgcagct gcgacaacca cagcttaaat ccgcccggcg gtttcgactg ggcagcaggt
     9121 tcaagtgtac tcatttttgc tccttaaacc gtcagcacca cacagctgtc cacttcccag
     9181 cacaaacgca cttcatcgcc ccaggtcggt aaccctttac gatgacgatg ggcgttttgt
     9241 agctgggcgc tgatcatctg cccacttttc agacgaacgt gatacaccga aagatcgccg
     9301 agataggcaa tgtgtatcac ctcccccacc gcgaagttac aaccattggc gggcggttcc
     9361 tcgcaaagca tgattttttc cgggcgaagc gccacatgca ccggcacgtt atcgaccact
     9421 gaagcatccg catcgacttt cagtggatgc accagtcccg gcgaataaag taccagacca
     9481 tcttcctgac gctctttgag tacaccttca aagacattaa ccgaaccgat aaattcagcg
     9541 ctatagcggg tggtcggatg ctcatagatc tcttccggtt cgccaatctg gacaaatttc
     9601 ccacgattca taatggcgat acgccccgcc atggtcatcg cctcttcctg atcgtgagta
     9661 accatcacgc aggtcacacc gacgcgctcc agaatatcca ccacttcaag ctgcatccgg
     9721 tcacgcagct ttttatccag cgcgcccatc ggctcatcga gcagtaatag tttcgggcgc
     9781 ttggcaaggc ttcgggccag ggccacacgc tgtcgctgac caccggaaag ctgatgcggt
     9841 ttgcgtttgg cgaactcctg catatgcacc aggccgagca tctcattgac ccggctggca
     9901 atttccgctt tcggtagttt gtcctgtttc aggccaaaag cgatgttctg ttccacggtc
     9961 atatgcggaa acagcgcata agactgaaac atcatattga tggggcgcag gtaaggcggc
    10021 acctgtgaca aatcgacgcc atcaagcatt atctgtccgg cagaaggttg ttcgaaacct
    10081 gccagcatac gcagcagcgt ggacttgcca cagccggatg cgcccagcag cgcgaagatt
    10141 tcacctttgt agatggtcag gctgacatca tccaccgcat gttgaccatc gtaggatttg
    10201 gtgaggttgc ggatttctaa tagcggcgtc agcgccttac gggttttcgc ctgcgggcga
    10261 gggatagcgt cattcacggc tgctctccgg cattgaatgt gtgcaagcgc accataatgg
    10321 tgcgaattgc cggcgggtgt ggtgcgcccg tccggcatct acgactgcgg attattttcc
    10381 gctcttcact ttggtccacg cgcgggtgcg cacacggtct atttttggat cctgcacttt
    10441 cagagtgaac aacttcgcac gaacgtccgc cggaggataa atccctggat tatcacgcac
    10501 ttccgcgctt accagcggcg tagcttcttt gttcgcgttg gcatagaaca catggtcgga
    10561 aatatgcgcc accacatccg ggcgcagcag gtaattcagg aactgatagg cttcgtcttt
    10621 atttttggca tccgcaggca tggcgaagac atcaaagaac gccatcgccc cttctttcgg
    10681 aatcgagaac gagacattaa cgccattctt cgcttccttc gcgcggtttg acgcctgcca
    10741 gacatcgccc gcccagccaa tagcgacgca gatatcgccg tttgccaggt cgttaatgta
    10801 ttgagatgaa tggaaataac gaatgttcgg gcgcagcttt aacagcagat cggttgccgg
    10861 tccggtgtaa tcatctgctt tagtgctgtt gggatcttta ccgagataat tcagcacggt
    10921 agcaaacact tcttccggtg catcaaggaa agagacgccg cagcttttca gtttttccag
    10981 attttcaggt ttgaggatca agtcccagct atcgacgggc gcgttttcgc ccagcaccgc
    11041 tttgacttta tcgacgttat agccaatccc ggtcgtcgcc cacatatagg gcatagcaaa
    11101 tttattgtcg ggatcgtgtt tggcgaccag cttcagcagc tccgggtcga gattcttcca
    11161 ctccggcaat ttgcttttgt ccagcggctg gaaaactccc gcagtcaact ggcgttcaag
    11221 aaagcttgct gacggcacca ccaggtcaaa gccggtgcta cccgccatta atttgccttc
    11281 cagtacttcg ttagagtcga aaacatcgta gacgacttta ataccggttt ctttttcaaa
    11341 attggccacc gtgtccgggg cgatataatc agaccagtta taaatgtgga gtgttttttg
    11401 ttcagccgcg agcgtgccga cagagacggc catcagagca cccgcaacca gacccgatag
    11461 ccatttttta tttaaggcgg tcatatctct ttccttctga aagttcgtta acaaacgaac
    11521 aaaagttgtc acactgaaag atatgcaata aacgtgcata ttttttatcg gcgcggtgta
    11581 agaaaagaga actctctccc ggccagcact gctcgctata taaaagcatc gcaagaataa
    11641 ctttagccag ggtttgagac tatagctcgg attaaaaaac ggtatttaac aaatttttat
    11701 gcgtatttgc tctatgtgat aaagccaaat cggcacaaga gaagtgaaac aatctttaag
    11761 aaaaggttaa aaacagcaga taattttgca gcacgcagtc gctgccgcag tgactgcgtg
    11821 ctcgaaagga gttatcagtg gaggaaatag ttttcagtaa cgttgttttg cccttcatcg
    11881 tcagtcggta acagcagttg atgggcatta gcttcaagaa tgaccatcga aatctgctct
    11941 tcgctctgac gcacgaacca tgcaaactgc tcataggtta cgccctgcat aacggataaa
    12001 gactggcaaa ccaccagctt tggcagatta tcatcctgca tatcaagaaa tgctttcacg
    12061 gtcagcgaac tggcattgat ggcagataaa tccgccgcca gcggcaatac ggctgaaggt
    12121 cggacttccg ccatggcaga aaacaggatc gtgttatcga tcagatcgat tttggcatca
    12181 aagacaccgt cgaaattctg catatggggc agatgcagag cctgacagtt atcacattca
    12241 aaaaaactca tccccaggtc atcgagccat tgacgcaacg tatccagacc aggaacgacc
    12301 agcgatgtca taattttgta caacctcttt cgataaaaag accggcacag cttacgcaaa
    12361 aagcgcaggc aaaaccatga tcagtaatgt gattgcgact aaccacccgt tttcaggcaa
    12421 tattccgtcg ttgcgtggcg ttcgatccag cggatcattt tacccgcgat gtcgataccg
    12481 gtggtttttt ctattccttc cagccccggc gacgcattca cttccatcac caatggcccg
    12541 cgattagcac gcaaaatatc tacaccagca acgtccagcg ccatcgttcg cgcggctttt
    12601 atcgcgattt cacgctcctg tggtgtgata ctggcgacgc ttgccgcgcc gccacgatgc
    12661 aaattggaac gaaaatcgcc ctctttcgcc cgccgttcaa tcgcagcgac cacttcatcg
    12721 ccaacaacca gacagcggat atcgcaccct tgcgcctctt tgatatattc ctgcaccaga
    12781 atatgcgcgt tcagaccgcg gaaagcgtca atcacgcttt cggccgcctg acgcgtctcc
    12841 gccagcacga caccaattcc ctgcgtacct tcaaccagct taaccaccag cggcgcacca
    12901 ccgaccatgt cgattaaatc gctggtatca tccggcgaat gcgcaatgcc cgtgacaggc
    12961 aggtcgatgc cctgacgcgc cagcagttgc atggaacgca atttgtcacg cgcccgggca
    13021 atggcgaccg actcattgag cggatagctc cccagcatct cgaactggcg cagtgccgcc
    13081 gtcccataaa aggtaatggc ggtaccaata cgcgggatca cagcgtcaaa atggggtaac
    13141 ttgcggcctt tgtagtgaat agaagacgcc gcaggattta tgttcatgta gcaagaaagc
    13201 ggatcaagaa tttcaaccag gtgaccacgc tgtatagcgg cttcacgcag ccgcttacac
    13261 gaatagagcg ttccatcccg ggacaatatg gcaattttca ccctgcacct ctctttcaga
    13321 cctggtcaaa agcccgcgta tcatacatcg acgtggcggt tttagcgcgt cgcccaaccc
    13381 tgtttgtgca aataatccag aataaatggg cggctttctt taatgattgt tcggcggata
    13441 tgatcgctcc aggtatcccg gcgattattg ctgccacggg tgaggtaata ttccgccagt
    13501 tgttcgtcat actgcgccag tgcgtcttta tccagcggtt gatagctgtt ttcatgcacc
    13561 aaaatggagg ccggtaaacg cggcttaaga tccggattat ccgcaggcca gccaaggcac
    13621 agcccaaaca gcggcagaac atgccgcggt aatttcagca gctccgtcac cgcttcaata
    13681 ttattgcgca ggccgccgat atataccctg cccaatccca gcgattccgc tgcggttaat
    13741 gcattctgcg ccatcattgc cgtatcaacg acaccgagca acagctgttc cgccaggccg
    13801 agctgagcat ccggacagat ctgtaaatgg cggttaaagt cggcacagaa cacccagaac
    13861 tccgccgctt gcgctacgtg tttttgcccg ccggtcagcg tcaccagttc ttcacgtaat
    13921 gctttgtcgg taatgcgaat aatgctacta cactgcaaaa aactggaact ggacgtcgca
    13981 cgggcgctgt taataatcgc ctcacgctgc gcttcggaaa tgggttcatc agtgaaatgg
    14041 cgaatggagc gatggccaca aataagttca atggttggcg tcattatctt tttctctttc
    14101 tgaacgtgaa tattgcgttg ggcggttcat cagctgtggg gcaagacgtt ttgccacctg
    14161 aagaataacc accaccgcag cgggaagcat gagcaaaaca ccgagaaaaa tcatcagaat
    14221 ctgcacttct ggccgagaaa atggctcagg cagcgacagg gagccgctta ccgacagcag
    14281 cgccaccgcc agcaacatca ttccgataaa ttccagtatc aacacgcttt taggcaattt
    14341 accgatcgcg cgcatacgct tccctctgca aaatgagcct tcagtctaaa acttttcacc
    14401 gtattgtgtt taacagttat agcttttagc aattaatgca acaggttaaa cctactttca
    14461 gcgaatacat tttagcgtga tcattacagg cataaatcta tgaggagaga aataatgcaa
    14521 accgttattt ttggtcgtcc gggttgccct tactgtgtgc gtgcaaaaga tctggctgag
    14581 aaattgagca atgaacgcga tgattttcag tatcagtatg tagatattcg tgcggaaggg
    14641 atcactaaag aagatctaca acaaaaggca ggtaaacccg tagaaaccgt gccgcagatt
    14701 tttgtcgatc agcaacatat cggcggctat accgattttg ctgcatgggt gaaagagaat
    14761 ctggacgcct gatcgtctga caagccctcg cgttgagggc tttattgatt ttttctgtgc
    14821 tgtggtttaa acaaactact gataaataag aaacacagtg cccccagcgc acaccagaac
    14881 accgcactta ataaccatgc cagctcttgc cagaatgagc gcgtcggtga aaaaaacagc
    14941 cgcataataa gcattgaaca gggtgccgcc agcattgcgc caaacagagg tttcaggact
    15001 tctctacgct gtgaaaagaa gctggcaact gctccaggaa gaatgaaaaa cagcaagccg
    15061 atttcaggat gcccggcagc ccgaaaagcg cctttcatgt gcgtcgccag aaaaaggcac
    15121 accacaatga agaggacaaa acagcagatt gcccccgccc aacgttgttt atgtttcact
    15181 cgttcctcct gacactgcgt ctatcgaaca catttttcgc cagtgtggcg ttcagtaaga
    15241 taaagccgct tcgcattcca tgctaatata ggccaacgca attcatatag ccgttgatac
    15301 ctaatgtgat tacactagta aaatatattg ttactttact atcgtttagg tgcgctgaat
    15361 gaatctgcgc cctgaattct ggtaaaaaac attatcgtaa attaccattt ctttcaacag
    15421 cttactagta aacaagaagt tagcctccgt gaatataaac gtcgccgaat tgttaaatgg
    15481 gaattacatt ctgttattat ttgtggtcct cgcgcttggg ctatgtctcg ggaaattacg
    15541 acttggttcg atccaactgg gtaattccat tggcgtttta gtcgtatcgc tgttattagg
    15601 ccaacaacat ttcagcatta acaccgacgc gcttaatctt ggctttatgc tgtttatttt
    15661 ctgcgtcggg gtcgaagccg gaccgaactt tttttccatt ttttttcgcg atgggaaaaa
    15721 ttacctaatg ttagcactgg tgatggttgg cagtgcgctg gtcatcgcct tagggttagg
    15781 taagctgttt ggctgggata ttggcctgac ggccggtatg ttagcaggct ctatgacgtc
    15841 aacaccggtt ttggtcggtg ctggcgatac actgcgtcat tccggtatgg aaagcaggca
    15901 gctctcactg gcgctggata atctgagcct cggatatgcc ttaacctatt taatcggtct
    15961 ggtgagtttg attgttggtg cgcgttactt gccgaaattg cagcatcagg acttacagac
    16021 cagcgcccag caaatcgccc gcgaacgtgg cctggacact gatgccaacc gtaaggttta
    16081 tttaccggtg atccgcgcct accgcgtcgg cccggagctg gtggcctgga ccgacggcaa
    16141 aaatctgcgt gaactgggta tttatcgaca aactggctgt tacattgaac gtattcggcg
    16201 taacgggatt ctggcaaatc cagacggtga tgccgtgcta caaatgggcg atgaaatagc
    16261 gttggtaggc taccccgacg cccacgcccg actcgatccc agtttccgta atggcaaaga
    16321 agttttcgat cgtgaccttc tcgacatgcg tatcgtcact gaagaagtgg tcgttaaaaa
    16381 ccataacgct gtaggcaaac gtctcgcaca actgaagttg accgatcacg gttgcttcct
    16441 taaccgcgtc attcgtagcc agattgagat gccgattgat gacaacgtcg tgcttaacaa
    16501 aggtgacgtt ttacaagtca gcggcgatgc ccgtcgcgta aaaaccatcg ccgatcgcat
    16561 cggctttatc tcgattcaca gccaggtcac tgacttgctg gcattctgcg ccttctttgt
    16621 tattgggctg atgatcggga tgatcacctt ccagttcagc acattcagtt tcggcatggg
    16681 gaacgctgcc gggttgttat tcgccggaat tatgctgggc tttatgcgtg ctaaccaccc
    16741 gaccttcggt tacattccgc aaggtgcatt aagcatggtg aaagagttcg gcttgatggt
    16801 gtttatggca ggcgttggtc tgagcgccgg tagcggtatt aataacggcc tgggcgcgat
    16861 tggcggtcaa atgttgattg ccggattgat tgtcagtctg gtgccagtgg ttatctgctt
    16921 cttgttcggt gcttatgtat tgcgaatgaa ccgcgcactg ttgttcggcg caatgatggg
    16981 cgcacgcacc tgcgcgccgg caatggagat catcagtgat acagctcgca gtaacatccc
    17041 ggcgctgggc tatgcgggca cctatgcaat cgccaacgtc ctgctgacgc tagcagggac
    17101 aatcatcgtc atggtatggc caggattagg ataaaactga agttgccctg aaaatgaaat
    17161 ttttttgcac aaccgcagaa cttttccgca gggcatcagt cttaattagt gccactgctt
    17221 ttctttgatg tccccatttt gtggagccca tcaaccccgc catttcggtt caaggttggt
    17281 gggttttttg ttgcctgaaa tttatgctgt ttaaaatcat gatgttaaaa gcactgtttt
    17341 ttaacgatgg cggcaaaatg gcggcagcgt caaagagaga gcgccacctg tcctgatttc
    17401 attggatgcg gctgaaccgg atttgactct tttggcgttg caatcgaacg aacaaaagtt
    17461 tcatgggtaa caaaagtatg gctgcagtta atgttctggc actggttgta acgctctttg
    17521 gtcaatgaag atacctgaaa actgctgcga gtatgggcgg cacttccaca cagtgggcaa
    17581 atcatcattt ttcgagttct ccccattttt gctaaattca caataatgat accgcattat
    17641 tccattttgc aaacttaaaa gttctccatt gcgaagaatc attccatttc gaaatcatca
    17701 atcctcactt caagctccag actggtcgta aaaccgttat ccgggctgac ggtatgcgtc
    17761 agagtcgtaa tgctccattc cgcatcatct atcggctgtt taaagccact gactttcact
    17821 ggcatttccg tgtagagatc tgcccgccct tccgccagtt gtagcgagaa tgacgcaacg
    17881 ccgcgttgca ggcgttccca ctgcattttc gctgcccgtt cggcgttact ccgattagca
    17941 taggtgcgat taagtaccag cacgttttca tccgtaccca ccaggtaatc gccctgcttc
    18001 gcttccggct ctttcttctg ctttgcggtc ctgcgcttac gcttcaccgt ggtgctttct
    18061 ttcttcgcgg gttcgcgggt atgcaaccaa ctggcaatta cgcccgtata ggctccgcga
    18121 tctgccaggg taaagcggtg actgtcgccg tccttgcgtg tgatagtgat caccggcaga
    18181 ggtttaccgc tggcgctttt gccctgtccc tgccggacga ataacagatt gccatttttc
    18241 accgacgcaa tagcaccgta ctggcgcgcc agccgcatca gaaaactgcc gtcactctca
    18301 ttggtctggt ctatatgtac cacgggctta tccgacaggt ctttacccag tgccatcttc
    18361 agcttgtgcc gcgcggctat ttccttcacc acttccccga cggtggtctt gtgccacgac
    18421 ttttcacgac gggtattcag cgtttcccga aaatcagcac ttcgcgcccg gatagtcagg
    18481 cggtccggtg cgccagtgtg ttcaatctcg tccaccgtga atgccccttt agggaaaagc
    18541 ggctgcccct tccagcccag cgccagcgta atgaccgcac cacggcgcgg cagcacgatt
    18601 tttccgtcgg cgtcgtccag ctccagatca agctggtccg cttcaaagcc ccgattgtcc
    18661 gtcagagtca aactcatcag gcggttatcc agcacagtgg tgatatccct gccctcaata
    18721 ctgatgctga atgcgggagt tttgttgcct ttgttaagca gttcagagct gaaattcacg
    18781 acagcagccc tcccaccgtt ttactgatat cacttaaggc agatgttgcc gtgtcctgca
    18841 gattattcag ctgcgtactg agatcaccga acatatcgga cagggattca tccacccgtt
    18901 tgagcgacag ggagaactca atccggcgcg gcataccgtc gcggaaaaac tccgtttcag
    18961 tcagattcag tccctcaatc acatacatgc cgtaaatcgt gccgctgcct tcaatcaggg
    19021 gccatgcttt tccctgttct gccatctgct ccagagccag caacgacagc ctgccgcccg
    19081 ttatctccgg cataagaaca ccagaaagcg tcagcatgtc gttgtccggt cccagaaact
    19141 gcgtggacgg acgacggttt acccggctgt ttgccgcatg tcgccagctg cgttgatact
    19201 gcagttcctg atacggaacg gtgcgcagca taaacacgta caatcccagc accatcatca
    19261 tgcgtcgtat cccccctgat cgctgtagtt actcctggct tttgccttca gcctgcgttc
    19321 acgttcatca agctggcggg ccacctcccg cgcaatatcc tgcgcacttt gtcctggctg
    19381 cgtctggatg atgatctgcg tcggtgcctc aatcctgtaa acgggcggca cagtggctgc
    19441 gcgactcaca attgcttctc cacctttcgc gggaagtgcc aaagggtgca acggtggaag
    19501 ctctgctggc gcggcagcaa cgcccatcat tccggcaaca acggcagcca gtgcagctgt
    19561 atttctccgg ctggtcacat ttgccgggcc gttaacaatt tccggcccgt tttcaccgac
    19621 gatgccaaac tgcccgcgcg ggatatagcc gccgctgtca tacatccccg caaagccata
    19681 tccccatgac ggaaaaccac ccgatggcat catcacttta ccgtctgcat tcaccgtcgc
    19741 aggttgctga cgcgtcacgc tttccggcag tttcgccttt gcagcctctt tactgacaat
    19801 gccgagtttc tccagcaacc aggaaacgcc ggatttcagg gagtccagcg gatgcatgac
    19861 catattcagc ccttccgcca gtgcctcccc gaatcgtcgc cccattgccg ctgcgctctg
    19921 cagttcggca gaggtcgact taacgggcgt cagcagatca gtaaaccagc cccacagcgc
    19981 ctgcactttg tcgccaatcc actgaaacac aggcttaagt ggttcgaatg cagcactgat
    20041 aggacctgcc gccgctttga atccttccac cacaccagcg agaaatgcgg tgatgggttg
    20101 ccagtatttc cagacaacca gcgccacgcc cgccagtgca gtaaccacaa gacctatcgg
    20161 actgagcaga gcacctaaca gaccagatat ggcatacagg gcaacgcgca gcatcgccag
    20221 cggaccggat gccagtactc gcagcaccgc gcctgcggca gccagtccac cgcgtagtgc
    20281 tgccagtgga ttcataaaca tcatagcaac agcacgtaaa ccggataatc cagaccgcaa
    20341 cagtgcaacc ggcacacctg ctacagtttt caggacattc cccgtcagtg atgcggtgcg
    20401 gcgcaaagac gacaacggcg cagtaagtaa acccgctgcg ttgcccgatg aagcaagccc
    20461 gcgtcgcagc agtgccagtg gagcgccagc taaccaggac aacgcgctgc tggttcgtgt
    20521 tactgctgcc gtaacggaag gtaacgtttt gatacccagc acagagaatc ccagacggat
    20581 gactgccagc ggccccagca ctgcagccag cgccaccgct aaggtgccga ggcctacggt
    20641 aaccgcagcc acaacagccg ctactttcat cagtgtgcct gtcagttccg ggttagcttc
    20701 cacccagcgg cgcaacgccc ccgtgatgct ttttaccgtg tacagaatat ccatcagcgg
    20761 ctggcgcagc gtttcgccca ggctgctgaa ggtgttctgc gctccggttt tgaccagcaa
    20821 ccactgagcg gaaagtgagt ccttgttgat gtcggattct ttctgcatgg aaccgagcgc
    20881 atcattgccc gctgtcagtt ttagctggcg ctgcagttcc ggaaggttgt ttgccagttt
    20941 cgctgcatca tcaccaaact ctttaccaaa caacatggtc atggcagaca gacgcttgtc
    21001 ctgcggcagt gcgttcacct tctccagcac acgctggata gttcccatcg catccttcgt
    21061 catctgcttt tcaatcactt caggattgag tttcagcaga ttcatccctt caaagaaact
    21121 cttgctttgc atggtggcaa tggacaattc acgcaccatc gcgtttgctg cactggctgc
    21181 aacctccggc gcagcgccca gtgtcagaaa ggtggacccc agtgccgccg ctttacgata
    21241 atccagacgg tcagccacac cgcccagacg ttgcataaca tcaatgatgt ccgccccttt
    21301 cgacatggcg ttatcatcca gatagttcag cgcatcgccg agctgttcaa tattgcgggt
    21361 aggtattttg tagagctggg cgattttccc cagactttct gacagttcat ccgctggcag
    21421 ctcaaaggct gttgccgcct ttgctgccgt actggcgaag gccagcaggt cacgtttctg
    21481 gtcttcccag ctgtcgtcag ggtttgcgac gttcatgcgc gcaccacctt caaccagtgc
    21541 agcgaagtcc accgcaccgt tttccatcgg caactgttcg ctggcagcct tgatggcatc
    21601 ctgcatttca taaaaacgtg cagtgcggtt gccattatcg tcacgcagac cattgacctg
    21661 ctttgccaca cctttcatgg catcttccat gctggtatag ctttttactg ccgccatcac
    21721 tggcgcaccc attgccagcc ctgcagccgt ggtagtggct ccggctcctg cgatgcgatc
    21781 gcgcacttca agccgtcttg agtattgttc tctggcagcg ttcatccgtg cctgttgttc
    21841 acccagacgt ttaagtgctt tttgctggcc ctccagtgcc tgccttgttt cttcagcatt
    21901 tttcttaagt tctcgctggg cactactgag ttgtctggta tcaatccctg attctttaag
    21961 tgcctgacgt tgtctctgga ccgcccccaa caagccgtta taggtctgct gaagttcctg
    22021 tactcgtgtt ttggcctgac tgaataactt tgcctgcgcg gcggttggcc tgttagtggc
    22081 agcaaattgt gtggcgagtt ttgccgcctc ttcgcgggct gcgttcaggt tgttggctgt
    22141 tatggctagt tgcgagcgcg tcttgcgaaa ttcatcaatt ctgccagcct gcttattcag
    22201 ttctttgagg ctgtttcggg tattctgaat tgcgccagcc agctctttcg aactggcctg
    22261 tgcagcacgg aatgggcggg tgagtttgtc aaccgcatta agaatgacct gcaggcgcag
    22321 gttattatca ctcatcgttg gccccgcttc tctgaatcgc tttataccgc cattccagca
    22381 cttcggtcag cggcataacg tcagtaacgg atggcggcca gtgaaagatg gtggcgatat
    22441 cagccaccag atcgtcaacc gtcaggctat cggtaaaccg gcaagcaccg acttcttcaa
    22501 caaaaaagtg acaacctcaa ccgacatggc agtgagatct gccgggtcca tctctgcaat
    22561 ttcctgtgca gtcagtgccg gactggagat gcgggggatc acggtcatca tcgcgttcac
    22621 atccatatcc ataatggcct gcaggcgtgt accgcgcagc gctccggact gcggtttacg
    22681 cagcacaatt tcggtaattt ctgttttacc gcgcttgata ggggtatcca gttgaatggt
    22741 cttttcagtc tgcttatcgc tcattttgtt gtcctgtaaa ttgggttctg gcgcggaatc
    22801 ccgcgccgtt cagatacatc agaggccgag ggcgttgcgg tgcgcttcca tcaggtccac
    22861 accgtccaca atttccacca tgttgataag gtccacttca tagagcacct caccattgat
    22921 ggtcagcttc gcgtagctgt tggtactggt cactttggtg gtgttacttt cgcccgtctt
    22981 ccactcaccg gaatccactt ctttgtgacg tccacgcacc acaagctcca cggcctgcac
    23041 ttccccggta tcgtcacgct ggatagagcc ggtaaagcgc aactggatgc catccaccgt
    23101 ggctttgccc atctgcttaa acagcagcag ttcagtacca ccaatggaaa attctgtgtc
    23161 cagcgcactg tcatcaagcc ccagatccac atccactgcc cccggcattc cgccgccgcg
    23221 atacttctca tatttgcggg tgaatttcgg cagcgtcagc gactcaacga tcccctgcca
    23281 gttgttcccg tcgttaaaca ggttcaggtg ttttaatttg cgtggtaaag ccatgttgtc
    23341 cccttacgcg ctgacctggc tggcgaaatt caccaggtac tgatcggtga tgcgctgacg
    23401 caacatcaga ttttcaagtg gcggcactgg cgtgtagtcg tagtcgatgg tgagttttcc
    23461 ggctttcaga gtgtctttgt cgttcaccga ctcgtccagc cagcaatcac caccaatgag
    23521 atacccctga ctgaccaggc tgcgcatttt ggcgcggatg ccctcgataa tgtcgcgcgc
    23581 cagcgacggg ttcagcggtt tgtccactgc ccacatgtgc gcttctgcca ttgtgtccgt
    23641 cagcacctgc gccgtgcggg tgtagttttc gaaagcaaag agcgggtcat cactcaggca
    23701 gcgggaaccc cagaagcgga aaccgtcttt acgcacaagc gtggtgacgt cgttctggtt
    23761 cagcagacct gcatcggttg ccgggtcctg cagatcccag aacacatctg cagaaattcc
    23821 ggtgacaccg ttcacgccca cgttggacag gcttttgtgc cacccagtct gctcatcaat
    23881 tttggcacgc agaccaagcg cacgggcggt ggcatatgcc gttgcttcgg cattcagcac
    23941 cgtgtcccag ccagtaaagt cgggccagat cagcattcct tcgcgctggc tgaagttttc
    24001 acggtaagtg atcgcctcct gtaccgtctt gcagccatac gctgacaggt aggcaaaccc
    24061 acgcaggctt tgcgccacac tcagcaactc agtcgcaacg gctttgttat cgtgacctgg
    24121 cacgccgaga atgcgcggtt taacgccgag ctgtgtctgg gcagataaca gggctttcat
    24181 gcctgttttt ttaccttcag cagtcactgc gccgatgata ttggtcgtgg tttcttcttc
    24241 cgtttcaccc tgcggcacac gcacaacaac ggtcacgggt tttgcctggt cagcgatggc
    24301 atccagcgaa cgggccagcg tgccggactc acccgcttta ccgctggcag tcagcacatc
    24361 agtgatcagc acgggtttat taagaggaaa catttttgca tcggcatcat cgcccgtgca
    24421 gaccatgccc acgatggcgg tgctcaccgt ggtaatggat cgggtacctt cgttgacttc
    24481 aacaacgcgc accccgtggt ggtaatcctg agccataagg cagtctctcc ggttgtagag
    24541 taggtctgac tatgttctgg ttgatacgca caggatgcac gaattgggat ttgtatggag
    24601 aatggcacaa cggtgatgaa aaaagccccg cagacgcggg ggtaggaatt taaaattgag
    24661 gtaattcggg ccagtaaata tcaggtacag tgctggtatc cgttgccatc accgcgtcaa
    24721 tgtaatccag cacggcgtta agtcgggtgt tttctgtctg cgtcagcttc ctcccggcct
    24781 gcaatttcag ttgaatcaga ctaattgaag ccattgcagt atcaatcagt gactggcgct
    24841 gtgcttctgc cgcttctatt gcggcaccgt attgtgcctc ggtatcggtt acccatttct
    24901 caccatccca tttatcgtat ggtgttaacg gagcgatagt ggtcatattt tcagggtaat
    24961 cccctggcgc tgtgatttct tttggttctc ccgtttcggt gctataaaca atttcaccgc
    25021 gatggtctgg cacatatttc cacgagttca aatccgttga gcggcaaatt gcataacccg
    25081 ttttatgtgt accaggtgca tctaaacaag aacatgccgg gataccgaca ccgacagcaa
    25141 gatattcggt tgatgttgag atatattcct gtgtcccatt atcatagtta taaacggtaa
    25201 tatcccctgc ctttaccgcg atcagcgcat catttaatac agctccaccc attatgcagc
    25261 cctcacgata taattaaatg aaatatttcg tggacgtgat tcgttaccga atttatctga
    25321 accatcagta tttctcgctg aatatgtttg gaggattgtc cctgatgatg gattcgcatt
    25381 atattcattt gttcctgctg gatagtatga cattgcacta ttgtcatctt tgaaaacagc
    25441 agacatcaat ccatcaccac cacttccgta agcagttggt aagaaatgac ggtgatcgaa
    25501 agaaagacta ttttgtgccg aaagtaggga acgaccagaa tctaccccgc gcccatcatc
    25561 ccagccacga ataaactcac cacgtaaatc aggcaattta tttgtcgggt aagccttcgc
    25621 cagttttgga tattcaacgg cagaaaaagc cgcaccgttg catttcagcc agccagtagg
    25681 cggtgtggct gaaggccacg gaacaggcac accaacgggt aatgccgaac cttctcccaa
    25741 accaaggtat gcgagaagac cagcaacatc ttttccactc aaattagtca gcgtattgtc
    25801 cagcggttgt ttgcctgaca gcgcattaag cattgttgtg gcaaagttcg gatcattccc
    25861 cagtgccgcc gccagttcat tcaatgtatc cagtgcagca ggtgcagaac ccaccattgc
    25921 tgcaatcgcc gatttcacaa aagccgtagt ggcaatctgt gtattgttga ccgactgtgc
    25981 cgcagtcggc gctgttggcg tcccggtaag tgccggactt gacagtgacg cttttagttc
    26041 cagcgcattg ttaatggtgg tgctgaattt cgggtcattg tttatggctg cggctatttc
    26101 tttcagcgtg tccagcgtgg ctggcgcacc attaataagg gccttcagtg ccgcctgaac
    26161 aaacgcggtg gtcgcaagtt gcgtggtatt attccccgcc gctggcgttg gtgctttggg
    26221 ggttccggta aacgtcgggc tggcttttgg cgcgtactgt gaatgcgggt ccagtgcggc
    26281 aagatgtttt gccatcagat catccacgta caccttcagc tccagtgcct tgtcatccac
    26341 atacttgcgg gttgccagca caacggcagg gtcgattttc agggtgatat tgtccgtgct
    26401 gctggttatc agcaccatgc gcacggtctg ggtgcgcccg ctgccttcag ccagtcgcgg
    26461 tttatagctt tccgggcagt tccccacggc aatcaatgcc cctgactcat caaacaggcc
    26521 cacttcacgt atccaccaac cgccctcgtt ttcagggatc acctgttcag caataatctg
    26581 gctgctgttc tgcgggtcga tatagagcat attcagcgca gcccggcgtt tctcatttac
    26641 cagtgcagtc tgctttgcgt ccggcgtcgg caatactccg ccgccatcgc ccaccgccat
    26701 atgggtaatt tttaaaggca caccgagcgc ggcggcgctg gcaagtttcg ccgcgccaat
    26761 atccgtcagc agggtataaa attttgtgct catggattca ctctcattgt gtcaataaca
    26821 tggaccgccc cgccttcatg cgcggtgccg ccggaaataa ttgtttcgtt gatatacgga
    26881 tagatcgtga tttcttcgcc aagatagctg gcggctccca cccaatgcgg gccgctggtc
    26941 tgcaggttga tggacatgcc gatcatgtga cggctacatg gtttggcatc gcttatcagt
    27001 cgctcaagtt ccagataggt atcttcagtg atgccctggt cctgcacacc aatgtccagg
    27061 cgaaacgtgc ccggtgtttc tccggtctgc caccactcaa taatgcggtt caggaagccg
    27121 aacggctcca ccacccgccg cacggcactg gtggttcctt tatgctgatg tatataaaaa
    27181 gcatccttta ccacctggcg tttgacgctt tccgtccagc cctcgtccca tcgatccaca
    27241 gagaacgccc aggcgagata aggcaggaaa ctgaccggac aggttgccgg attccacaag
    27301 tcacgaagcg gcacctgcag atcagaaatc ccgctgcagg tttgcgccag tcggcgctcc
    27361 agtggtgttg aacccggtgg cagcagacta ttcatccgtt cctccgttgg ttacgctcca
    27421 ctgcgtacat gatgccgcct gtgttttgtt caggaccaca tccgccagcg gtgaagccag
    27481 ctccacacgc tgcacaccct caacatgcag ggcggcaaag atggcactac ggcgaatatc
    27541 ccgaccaagc cgcgtctgac tggcgatgta cttctgcagg ctggcttttg ccgctgccat
    27601 taccggctct gcttccggcc ccggatagag aaaaatggta gcttccacgc ggtacgggat
    27661 gatttctgcg ctgcgaaccg tcagacggtc agccaccggg cggacgttct cactgttcag
    27721 ggctttctcc accacatcca gcaggtcttt ttctgctgtt ccatcgcctt cgcggctaag
    27781 gacagtcagc accacctctg caggtgccgg actggttgca ctggcatccg ccacccgacc
    27841 gtcggcgctt cgtgcatgaa attcataagc ggcagttggc cccgcaactg aaagtccttc
    27901 aaaggctgca ggcacacgca ggcgtaacgc ttcatcgctt tccatcacag ccgcaacggg
    27961 cggcacagcg tcattatcag caggcgtcac cgtcaggcgt ttcacgttgt agttggcagc
    28021 gagctggtcc agatcgccgc ccatcgcata agccaccatc accgcctgcg cggcttcgtt
    28081 aatacgctgg cgcagaagca actcacgata agcgttctcc tgcaataatt tggtgacggg
    28141 ttcagattcc agttccagcg tgcggatcac tgcttcctgc tcatctttcg gatgaagcgc
    28201 cacaaattct gccttgcgtt cggcaagcag cgtctcaaag tccggcacat ccacaatctg
    28261 cggcgcagat aactgcgaaa ggtcaatcac tgccattctc tgctcctgtt gatacggaaa
    28321 gggacacagg cacaccgtta ttccgccgcc cggtcagctc caccaccata gaaccgtcaa
    28381 agttgctgtt gatggtgatg gaatccagcg tcagccgtgg ctcccagcga ctcagcgcca
    28441 catacactgc cgacatgacc tgcaggcgta atgccggatt ttgtggctga tctattaaaa
    28501 ccgacaggag ggaaccatat tcccggcggg caatgcggct accctgcggt gtcagcagaa
    28561 tgtcccgcac cgactggcgc agatgatcaa tatcagtaat gactttgccg ctggtattgt
    28621 tcatcccgct ataaagcgtc ataccgggcc tccggttgta tcgccgcctt tcaggacgcc
    28681 agtatgctga tgtgcatcaa ccacaatccc gttagaactc atcgctccgc cgccctgggt
    28741 aacgccacca ttgatcacca cttcgctgtt aatgcgcgtg cggtcagcct ccagtacaaa
    28801 ctcactggtt ttcatggtga tgttatcagc ggcctcaatg accattgatt tgatgcccct
    28861 gacataccag cgcccggtgg cgggttcata ttcaaaccag ccaccgtcag gatgttctgt
    28921 cacgcaggcg tccgccgacg tcgacggtgg tgcgaactga ttcgaataga cagcgggcag
    28981 cgcaaaggca gtctccagat tgccgcccag actcagcagc accacctgct caccttccga
    29041 tggtcgccac catgtgcggg cattcccggc acgcagcgtc agccaactga tccagttagt
    29101 ttcaaggtcg cccgttttca cccggcaaag ccagttctcc cggtccactt cggtaactac
    29161 acctgtgcgg atcaggttgg tgataaggcg catgatttcg gttaattgtg cgttcataga
    29221 tatatgatga cagatgaaaa tttgtttata acttcttgca aattgtggta tcgatggtac
    29281 aaattgacaa aaggataaaa aacaaccaat aggtggataa atgagtgtta tgaatccaat
    29341 aagttctaat atatttaatg ctgaattttt aaacacccca gcagcggcac ttgccgcatg
    29401 gatttccatt attggagctg ttataacttt ggtgacgata gttataagag cactattcaa
    29461 atatagaaaa tctcatgatg taattttgaa aaaatcagga atacctgcgt ttatattaaa
    29521 tttttttctt ataaaaatat cattaaaaag gctgcctact atcacatggg ctgaaaaatc
    29581 attcacggtt ctattttcgc ttcttttttt gtgtgcaatt tatctttttg gtccagtttt
    29641 catccaagcc attagaaccc caccaaatag cacattgctt tattggataa agtccggtga
    29701 atcattttat atgtcaaaaa aaatggcgac tgcagctaca atattaacca ctcctgattg
    29761 ggaaatatca aaggatgatt gcgaagagtc atcctctgcc agtacagaga agtacaaatc
    29821 attaactatc gaacataaag aaattctttg taaactacta accactgatg aagggaatgc
    29881 ttacattgat gaagaagtca agaatttcgt taaagacaaa ttttttatct attcctttgc
    29941 cccaacaact atatttattc tattatggat ttctttgggt tttatactga ccattcacta
    30001 ttctaaaaaa gttaggaaat atattctaac tgaacaaaaa aatgcaattc attgggcata
    30061 tggtgaattc aagacagaag gaatctattc aatatatcaa gagttagaac ataagactca
    30121 ccattaagac ccagcaggcg gcgctctgcg taacggacct ccggtccttt gcgactgacg
    30181 cgatcacgca ggccgtaatg gtgaacacgg gcaatacgct gcaccttgcc ttcaaactgt
    30241 acgctggcag agtcggcgct ggcggcagtt ttcaggtatt ttgtggtgcg cagctttgca
    30301 aacatctgac gtttgatgcg gccttttttg ctgcgtgctg ttaccctgcg cggttcataa
    30361 ctgctgccat caggattgcg ctgcatcctg atattctgct gctgtgtccg gcgcagttcc
    30421 tgcgccagct ggcgcatcat acggcttctt gcggctggct ccagattcgc cagcaaggca
    30481 ctcagccagt cgtccacctt ctgcaattca gccacgtttc accgtccaca tttcttcagg
    30541 ttcatcgggt tccgctacag cttcaacgct ggacactgtg ccgtcagtgc tgaccagcac
    30601 acgttccgtc agttgcaggt taaggctgat atcacagaca tcgttgcgca gaatatccac
    30661 ctcaaaggtg aataactttt cccgtaaagc gggattattg atggcatcgg gctggttatc
    30721 acgcagccac agcaaaaccg gggccatcaa cagattctgg tcaccactga aatcctctat
    30781 caccacgttc agggtgtagc ggtactccca tgacatggag ctggcccccg tggcaaccag
    30841 cgaaccgtta tccacaaaca gatgcagttt gtccgggtta ttacggacat aaggcactgc
    30901 tttattaagg gcgtggcgca gggattgtgg tttgttcact gtttcgctcc tgacacgcaa
    30961 taatcatgtc cactttgtct gcacagaccg cccaggcggc ctccgtttca tccagcaacg
    31021 cgttcaggtc accgttagtg cgcggcgctg cctgccccag ccgacacggc gtcactcgcg
    31081 gacaaccact gacggtaagc tgcacctccg gtgagtgtcg ggcgttcccg cagccggata
    31141 atgtcagcag gcaaaggagt atcagcccag cggcgtaaat cctcgttctc acgtttcagt
    31201 tcctcaatcc ggtgttgtcg ttgtctcagt agtgcgctgg tctgttctgc gtcggcataa
    31261 agtcgcgcct gctcccggtt gttggtttct gtcagaatgg acaggctgat aagctggctg
    31321 ttgctctttg ccagtgcctg gcttttgctc cgaagctcat ctgcctgcgt gctgatggtc
    31381 tggctggcat cagccagccg ccacgtcttc cagcccagcg ccgccagtaa taacgccagc
    31441 acaaccagca gcaaccggtt catgctgcta cctgttgcgc catctgatta cgggtgatcc
    31501 agaaggcaat aacggtcagt agataaaaga ccagggtaat agcccacccc gtccaggcga
    31561 gactgacgac aatcagcaat cgcatcatcc agctgataaa tacgttttct tttcgggtaa
    31621 tggtcttcag caaagatgcc ctcaactcct gccagagcgg gccgttctta attaacgcag
    31681 ccagtgctac cggaattgcc ccccatgtca gcagacaggc tacccagaca ccagatgctg
    31741 ccagtaccgg aaaaatcccc tgcggataca ccattgcggc gattaacagc gctatccata
    31801 acatcagaaa cagcccgctg attaatttct ttttcatttc agtttgctcc ctgtaagcac
    31861 caggccatct cccgcgcacg gcggttatcc agcccctgat taaacacacc ttttacatac
    31921 acccagcgcg gcaactgtcg gcacgcatcc gcccagcgcc gctgattgag caatttcacc
    31981 agcgtggaac tgcaggcatt gcccgtaccc acgttgaagg caaacgacac cgcagcgtca
    32041 tacaccttct gcggcggctg ttgcttcata cacctttcca gcgcccgctc cacacgcagc
    32101 acgttggaga tcagcccttc tgctgcctgt cgctccgtaa tggttttgcc gggaatgacg
    32161 cccgacgtat taccaatgcc gtcggtccag acacccgcgc tgcactgata cggctgcaga
    32221 cgacaacctt cgtaatcggc aatcagtttc agcccctcca cggaggtgtg aagctgctga
    32281 aaacccggca gcgtggcagc aatagccagc acggtcccga caaggcagcg tttaacgatt
    32341 gatggattca tagtcctccc gcgagatctg cccgtcgcgc agaagctggt aggctttatg
    32401 tttgtagtac cagttgatag ccagcatcag cacaccaatc atcagaccgc ccagcgttga
    32461 ggcatccttg atggacaaat cgcccagcca ggccagcaca acggcgatgc agtacgtgat
    32521 aaaggcgctg attcgctcaa gcgtcataat tcagtcccat agctggacgg tctgcacggt
    32581 ggtggtggtc ggaatgtccg gcagctccac ctgcagcccg tgaggtaaaa aggggccgta
    32641 ttcggcaagc cccggatttg ccttcagtac ctgctccgtg acaccctgcg tgcgcccgta
    32701 atgacgccag caaagtgcat ccaccgtgtc atactgatgc gctcgcactt tcatcagata
    32761 agctccactg tgcagtgcgg cgcgtcctgt acccggctga tggcccagcg ggcgtcacgc
    32821 cataaatcac cgctggcttc cgccagttcc tcgcctcgct tcacaccgga tgccgtggcg
    32881 tcatagtcct ggtatcgttc gttgagcatg gcgcgtgccc agcagtaaac cgcgttgaaa
    32941 tagtgctgaa tgcgctcact tttgccgtcc agctgttctg ccggaacctc tgccagcgag
    33001 gcatacccca gcatctgctg gcgtctgcga aactcataca gctctgcgtt gacctccgaa
    33061 attgccgaca gcgcaacctg ctttaaacgc ggctgcgtca ccgtgccgtc agtgcgcatg
    33121 acactgcgaa actccgacaa gtccacatca ggccagaacg gcgtattcct gatgatttcc
    33181 gcctgttccg gtgcctgttc tggcgcaaca aacttcatgc tgctttctcc tgaaatagag
    33241 ggcggtggac ggggttttga tgtggcagtg cctttcgcca ccccgtgccg cccgtgcgcg
    33301 ggggcacgtt ctgtcagcgg ctgtcattgc gcagtctgcg ctccagctgc tgtttgtctt
    33361 ttttcacgcc acagcgggga tcgagctgta acgcatggtt gagatgatta agggcggaag
    33421 ccggattact ttcactcagg acagcgccaa tcgctttatg cagacgcgcc cgtgactggt
    33481 ccggcatatc cagaccatct gtcagctcca gcgtctgcag caacagagcg gcatcaaagc
    33541 cggtggcggc aagcattgcg ctctgcgccg cgtctgccat ttcctctgcc agcacggtct
    33601 gcacgttgcg gttacccagc ggcatcaccc agccatgacg cagggcatga cgcccgatct
    33661 ccagcgcccc ggcataatct ccggcatcaa tgcgccacag catcacgtac atcagcacgt
    33721 catcctgttg agcgcctccg gcagccagaa cgccctccgc ccaggcagca tatttcggca
    33781 gcagctccac cttgatttcc gcttttttta ccgtggactg aacgcccttg agacggcgac
    33841 ggtcttccgc cagttgcagc agcatcaggt catagcccga cgcgtggcga acactgccac
    33901 cctcgcgagc ggcctgttca gcctgaacgc gcaggcgatg ctgccgtgcg ggactcaggc
    33961 tcatgaatta cgctccggtt tctgctgcgg cggcgctgaa gtcaccaatc tggatgtttt
    34021 ccaccagtgc agcgcagcga tagtcctcaa ccacataggc ttcgttaacg gattcaaaat
    34081 tttcaatccg gtcacgtttc gggttgtcga taactgaacg gcggcgggta tcttcctgcc
    34141 agtagatgga caggttatcc agacgggtga tcagcagcgc attcggcggg aagaacggcg
    34201 cacgcaccgc ctgcaggccc cccatgcgtt tctgactgat gatcatatcg gcagccagtt
    34261 tttcactgtt ttcctgctct ttgttgacca gcgggaaata cttgtcagac agcagttcac
    34321 gcccgcaaat caccaccaga tcgtcatcgt cctggtagac aacgtcgata agctcattga
    34381 ccgcatccat caccacggcg tccaggttgg catattcgcc ccctttcccg actttcaccg
    34441 cacccggtgt ggtttcaccg cccgtggtgc tgctgcccat gacatgatcc ggtgcatcct
    34501 cacggatttt ctgtaaccag cctttgttca catcctgcag cagcgggttt tcgctacggt
    34561 tggaggtttt cgcacgcttc acgccgttaa agccgatcat gatgcggtcc agtgcctgac
    34621 gtttcacgat ggcgtcacgg atacgcacct ggaaatcctg aaacttcgcc cacagatcca
    34681 gcttcgcgta ggtcagcacc gtgtcaaagt tggtctgctc gcatttatat tccacatcga
    34741 ccatcagcgt cggatcgaca ggctcacgct ctttcgcggt ggtatcagtg gttccagcaa
    34801 tggtgctgcc aacacccaac cccagcagct gaccggattg ctcagtcact ggcgtgacgt
    34861 taatcagcgt caggaaagcg gcggactgct ggatctggtc ttccagagtc tgctgtacag
    34921 acggctctac ggtgaatttg ctggacagtt cttcaactgc cacaccgttc agacgcgcca
    34981 gttgctgcag gtaagcgtta aaagcaaagc gggtattctt cttcatcagg ttttgtgctc
    35041 catcagcaat tggtcagagt gtcagcgggg gcgttaccgc ctgttgcacg ctggcggtag
    35101 tcctggcggc tgtcttcttg gctcagcttg tccaccagtt cgttaaaggc ggtctgctgt
    35161 gcctgcaggg cagtctccag ctcagacagg cgttcttcct gctcagacag ggatttttcg
    35221 gtgcgcgcac tcaggttctg ctgctcagtg gcgaccagtt ccacggcctt atgcacatca
    35281 gagaaccggg cgtcatcgga ctgctctttt ttggtgaaca gcgccgtgac acgggcaaac
    35341 agggacggtt tgtcatcctg gatttcttcc agttcgatca ccgtttcctc tgcagcggta
    35401 aaaagattgg cgggattctg cttgcggttt gccagcgggt tatgggctgc actggcgctg
    35461 aatgtcagca tttccgtacc cagactggca gggtcatcag tggcagccag gccaaccagg
    35521 taggctttgc ccgtatcagc gaacttcgga ctgacttcca tagatgtgaa taatttctgg
    35581 ccttttttca ccagctccac cagggactcc gttggctcaa cgtcggcata cagcgccatc
    35641 tttcctgcca gcggaccttc cgtgatttct tcagcaaaca gcgccgtcac cttgccgtag
    35701 cggttaaagg tgctgtccgg cagataagac ttgatgtgct caaggttaat cagcgcggta
    35761 tacaccgccg ggttgtagct ggctgccatc tgttccagcc attcacgctg gatttcgcgt
    35821 ccgtcggtgg tggcaccttc caccccgatg cgaaaacgct ttgctttcac tgtcatgagc
    35881 cgtgctccgt tagaaaaaac ttactggagc cttatggttg cggtgatgtg ggcagtgaaa
    35941 caatgcgcgg tatttgtacc gacaaccaca caaaccgcag gcggggaaag ccttcattca
    36001 aggctgtagg tttgtgccat gaacaccaca ctgacacccg cagatctcga tccccgtcgg
    36061 caggccatgc tgctgtactt tcagggatac cgtgtagccc gcattgctga aatgctgggc
    36121 gagaaagttg caaccgttca cagctggaag aaacgcgaca agtggggtga ctatgggccg
    36181 ctggatcaga tgcagctcac caccgccgca cgctactgcc agctcattat gaaggagcac
    36241 aaagaaggga aagatttcaa agagattgac ctgctggcgc gccagtcgga acgccacgcg
    36301 cggatcggca agtttaacaa tggcggcaac gaagccgact taaaccctaa cgtcgccaac
    36361 cgcaacaaag gcccgcgccg tcagccggaa aagaatgttt tcaccgatga gcagattgag
    36421 aagctggtag aaatcttcca ttcctctatg ttcaactacc agcgccactg gtgggaagcc
    36481 ggaaaaacca accgcatccg caacctgctg aagtcacgcc agatcggcgc gaccttttac
    36541 tttgcccgtg aagccctgat tgacgctctg cttaccggac gtaaccagat tttcctttcc
    36601 gccagcaagg cacaggccca cgtctttaag cagtacatca tcgacttcgc caaagaagtg
    36661 gaagtggagc tgaaaggcga tccgatggtg cttcccaacg gggccacact gtatttcctc
    36721 ggcaccaatg cccgcacggc ccagagttac cacggcaacc tgtatctgga tgaatatttc
    36781 tggataccga aattccagga gctgcgcaaa gtggcttccg gtatggctat tcacaaaaaa
    36841 tggcgacaaa cctatttttc cacgccatcc agcctgacac acagtgctta tccgttctgg
    36901 tccggtgcgc tattcaaccg tgggcgcaat aaagccgaca aggtggacat cgacctgtcc
    36961 cacagcaatc tggctccagg cctgctgtgt gcagacgggc aataccgcca gatagtcacc
    37021 gtggaagatg cggtgcgcgg cggctgtaac ctgttcgacc ttgaccagtt gcgcatggaa
    37081 tacagcccgg acgaatacca gaacctgctg atgtgtgaat tcgtggacga tctcgcgtcc
    37141 gtatttccgc tcagcgagct gcaggcatgc atggtggaca gttgggaagt ctggaccgac
    37201 tttcatgcac tggccctgcg cccgtttggc tggcgagaag tgtggatcgg ttatgacccg
    37261 gcaaaaggta cgcagaacgg cgacagcgcc ggatgcgtgg tggtggcacc gccagccgtg
    37321 ccaggcggta agtttcgcat tcttgagcgt caccagtggc gcgggatgga cttccgcgcc
    37381 caagctgacg ccatcaaaaa actgaccgaa cagtacaacg tgacctatat cggtatcgac
    37441 tcgacaggtg tcggtcacgg agtttacgag aacgtgaaag cgttctttcc tgccgtccgg
    37501 gagtttgtct acaaccccaa cgttaaaaat gccctggtac tcaaggccta cgacattatc
    37561 agccaccgcc gtctggagtt tgacgccggg cacaccgaca ttgcgcagtc attcatggca
    37621 atccgtcgtg ccaccaccgc cagtggcaac cgcccgacct atgaagccag ccgcagcgaa
    37681 gaagccagcc acgccgatct ggcctgggca acaatgcacg cactgtttaa cgaaccgctg
    37741 cagggcgagt ccgccaatac cagcaatatt gtggagattt tttgatggga aagagtaaga
    37801 aaaaccgcgc tgcggcgacg aatcagatcc agcataaaaa ccagacttca gccgaagcat
    37861 tcagcttcgg tgatcccgtt ccagtacttg accgccgcga actgctggac tatgtggaat
    37921 gtgttcagac agatcgctgg tatgagcctc ccgtcagctt tgacggactg gcgcgcacct
    37981 tccgcgctgc cgtgcatcac agttccccga ttgcagtaaa gtgcaacatt ctgaccagta
    38041 cctatatccc tcatccgctg ctcagccaac aggctttttc gcgttttgtg caggactatc
    38101 tggtatttgg taacgcctac ctggagaaac gcacgaaccg attcggtgaa gttatcgccc
    38161 ttgagcctgc gctggcaaaa tacacccgac gcgggttaga cctggatacc tactggtttg
    38221 tgcaatacgg tatgacaacc cagcagtatc agttcacgaa aggcagcatt tttcatctga
    38281 tggaaccgga catcaaccag gagatctacg gcctgcccgg ctatctttct gccattccat
    38341 ccgccctgct caacgaatcc gccacgctgt tccgccgtaa gtattacatc aacggtagtc
    38401 atgcaggctt catcatgtac atgaccgacg ccgcgcagaa tcaggaggat gtgaacaacc
    38461 tccgcaacgc gatgaaaagc gccaaaggtc caggcaactt ccgcaatctg tttatgtact
    38521 cgcctaacgg caaaaaggac ggacttcaga ttatcccgtt gtcagaagtc gcagcgaagg
    38581 atgagtttct gaatatcaag aacgtgagcc gcgatgacat gatggcagca caccgagtgc
    38641 cgccgcaaat gatggggatt atgccaaata atgttggggg gtttggggat gtggaaaagg
    38701 ccgcgaaagt atttgttatg aatgagttac taccaattca aaaacatatt ctgcaactta
    38761 atgaatgggc taaaaaaaac atcatctcat tcagtgaata ctcagtggag tgtatgtaaa
    38821 ttgaataatg gcaggtacta tacctgccac tgaacttata ttttagcaaa cgtttctaac
    38881 gccaagccat ctgttctttc ttttattaat gaatcatccc atttatgttc tcttgcttct
    38941 gactcactaa caaactctgt aactaatttt aaatcagatt ttttataaga ttctattttt
    39001 ttgtgcaact cataattttt
//
LOCUS       DADXDL010000038        38630 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.038, whole genome shotgun sequence.
ACCESSION   DADXDL010000038 DADXDL010000000
VERSION     DADXDL010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38630
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.038"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..835)
                     /locus_tag="IRB70_002281"
     CDS             complement(<1..835)
                     /locus_tag="IRB70_002281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0632191.1"
                     /translation="MMKIEPSILPSLAWFALIVRAGSFSRAASEMGITRAALSQNLKS
                     LEERLNTKLIYRTTRNMSLTEEGQRLYEVLVSALGQIDDALKDVGDTQLEPTGLLRIN
                     SSRVAARMLVEPHIGEFLTRYPKTKIELIMDDGLSNIIADGCDVGIRLEQGLDEHMTA
                     VPVSPLIKLVTVASPDYLKEHGIPETPQELSNHNCLRLRHKSSGALSAWEFSNVVGGN
                     EEFEIEVSGKYISNDDESMIRMALNGTGIIQHLDFAIAEHINAGKLQPILEDWAVSFP
                     GF"
     gene            992..1912
                     /locus_tag="IRB70_002282"
     CDS             992..1912
                     /locus_tag="IRB70_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBC0632192.1"
                     /translation="MKTVSIKHTYWDIAADIYFPDDFNSEKKYPAIISAHPIGSCKEQ
                     TSGSVYGAALAKAGFIVIAFDASFQGSSGGEPRYLEDPTMRVKDFSIVVDYLTSLPYV
                     DAGRIGVLGICGGGGYAINAAMTERRIKAIGTVTGANYGRLMREGFTAFNPIGALEAM
                     AQQRTDEANGAKLRVDDLLPSSPEAALEAGLTEIDLFEATEYYRSPRGCAPNGVNRSL
                     FSHQTVAVGWDAFHLAEVLLTQPIMVVVGDRVGAFGAYRDGCEIIGRAASKHKELVVV
                     EGYSHYDLYDKPEPVKQALDKLIPFYKTHL"
     gene            2157..3299
                     /locus_tag="IRB70_002283"
     CDS             2157..3299
                     /locus_tag="IRB70_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBC0632193.1"
                     /translation="MTNKHPSLFSPFMLTEKIKLRNRIVMAPMTTWSANPDGTISEQE
                     LEFYKRRSQNVGLVITGCTYVTPSGIGFTHEFAAYDDRFINSLEKLAAAAKSGGAPAI
                     LQIFHAGNKAIPELVPNNDVISASASSVKSGDFMKRVVQSREMTENEIQETIRAFGDV
                     TKRAIKAGFDGVELHGAHGFLLQNFFSPLFNQRNDRWGGDLEGRMRFPLAVLQEVKNV
                     VYEYATKPFAIGYRISPEESATGGLRIEDTYKLLDRLISSGISYIHTSLVSINDSYPV
                     ESPNGPRTIELILNHIAGRVPVIAAGKIRTPSQAQEAISTGLPLVAIGKGLVINPEWV
                     TLAESGRDHEIQTTLNPQLVHELTIPDKLWDQIQTSKGTGWFPLMD"
     gene            3773..3874
                     /locus_tag="IRB70_002284"
     CDS             3773..3874
                     /locus_tag="IRB70_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632194.1"
                     /translation="MKENKVQQISHKLINIVVFVAIVEYAYLFLHFY"
     gene            4239..4502
                     /locus_tag="IRB70_002285"
     CDS             4239..4502
                     /locus_tag="IRB70_002285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBC0632195.1"
                     /translation="MKPNIHPEYRTVVFHDTSVDEYFKIGSTIKTDREIELDGVTYPY
                     VTIDVSSKSHPFYTGKLRTVASEGNVARFTQRFGRFVSTKKGA"
     gene            4502..4642
                     /gene="ykgO"
                     /locus_tag="IRB70_002286"
     CDS             4502..4642
                     /gene="ykgO"
                     /locus_tag="IRB70_002286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L36"
                     /protein_id="HBC0632196.1"
                     /translation="MKVLNSLRTAKERHPDCQIVKRKGRLYVICKSNPRFKAVQGRKK
                     KR"
     gene            complement(4712..4902)
                     /locus_tag="IRB70_002287"
                     /pseudo
     CDS             complement(4712..4902)
                     /locus_tag="IRB70_002287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308353.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            5726..6268
                     /gene="ecpR"
                     /locus_tag="IRB70_002288"
                     /gene_synonym="matA"
     CDS             5726..6268
                     /gene="ecpR"
                     /locus_tag="IRB70_002288"
                     /gene_synonym="matA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECP biosynthesis operon DNA-binding
                     transcriptional regulator EcpR"
                     /protein_id="HBC0632197.1"
                     /translation="MECQNRSDKYIWSPHDAYFYKGLSELIVDIDRLIYLSLEKIRKD
                     FVFINLNTDSLTEFINRDNEWLSAVKGKQVVLIAARKSEALANYWYYNSNIRGVVYAG
                     LSRDIRKELAYVINGRFLRKDIKKDKITDREMEIIRMTAQGMLPKSIARIENCSVKTV
                     YTHRRNAEAKLYSKLYKLVQ"
     gene            6343..6930
                     /gene="ecpA"
                     /locus_tag="IRB70_002289"
                     /gene_synonym="matB"
     CDS             6343..6930
                     /gene="ecpA"
                     /locus_tag="IRB70_002289"
                     /gene_synonym="matB"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="common pilus major fimbrillin subunit EcpA"
                     /protein_id="HBC0632198.1"
                     /translation="MKKKVLAIALVTVFTGTGVAQAADVTAQAVATWSATAKKDTTSK
                     LVVTPLGSLAFQYAEGIKGFNSQKGLFDVAIEGDSTATAFKLTSRLITNTLTQLDTSG
                     STLNVGVDYNGAAVEKTGDTVMIDTANGVLGGNLSPLANGYNASNRTTAQDGFTFSII
                     SGTTNGTTAVTDYSTLPEGIWSGDVSVQFDATWTS"
     gene            6988..7656
                     /gene="ecpB"
                     /locus_tag="IRB70_002290"
                     /gene_synonym="yagY"
     CDS             6988..7656
                     /gene="ecpB"
                     /locus_tag="IRB70_002290"
                     /gene_synonym="yagY"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpB"
                     /protein_id="HBC0632199.1"
                     /translation="MKKHLLPLALLLSGISPAQALDVGDISSFMNSDSSTLSKTIKNS
                     TDSGRLINIRLERLSSPLDDGQVISMDKPDELLLTPASLLLPAQASEVIRFFYKGPAD
                     EKERYYRIVWFDQALSDAQRDNANRSAVATASARIGTILVVAPRQANYHFQYANGSLT
                     NTGNATLRILAYGPCLKAANGKECKENYYLMPGKSRRFTRVDTADNKGRVALWQGDKF
                     IPVK"
     gene            7682..10207
                     /gene="ecpC"
                     /locus_tag="IRB70_002291"
                     /gene_synonym="yagX"
     CDS             7682..10207
                     /gene="ecpC"
                     /locus_tag="IRB70_002291"
                     /gene_synonym="yagX"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial usher EcpC"
                     /protein_id="HBC0632200.1"
                     /translation="MPLRRFSPGLKAQFAFGMVFLFVQPDASAADISAQQIGGVIIPQ
                     AFSQALQDGMSVPLYIHLAGSQGRQDDQRIGSAFIWLDDGQLRIRKIQLEESEDNASV
                     SEQTRQQLMALANAPFNEALTIPLTDNAQLDLSLRQLLLQLVVKREALGTVLRSRSED
                     IGQSSVNTLSSNLSYNFGIYNNQLRNGGSNTSSYLSLNNVTALREHHVVLDGSLYGIG
                     SGQQDSELYKAMYERDFAGHRFAGGMLDTWNLQSLGPMTAISAGKIYGLSWGNQASST
                     IFDSSQSATPVIAFLPAAGEVHLTRDGRLLSVQNFTMGNHEVDTRGLPYGIYDVEVEV
                     IVNGRVISKRTQRVNKLFSRGRGVGAPLAWQIWGGSFHMDRWSENGKKTRPAKESWLA
                     GASTSGSLSTLSWAATGYGYDNQAVGETRLTLPLGGAINVNLQNMLASDSSWSNIASI
                     SATLPGGFSSLWVNQEKTRIGNQLRRSDADNRAIGGTLNLNSLWSKLGTFSISYNDDR
                     RYNSHYYTADYYQSVYSGTFGSLGLRAGIQRYNNGDSSANTGKYIALDLSLPLGNWFS
                     AGMTHQNGYTMANLSARKQFDEGTIRTVGANLSRAISGDTGDDKTLSGGAYAQFDARY
                     ASGTLNVNSAADGYINTNLTANGSVGWQGKNIAASGRTDGNAGVIFDTGLENDGQISA
                     KINGRIFPLNGKRNYLPLSPYGRYEVELQNSKNSLDSYDIVSGRKSHLTLYPGNVAVI
                     EPEVKQMVTVSGRIRAEDGTLLANARINNHIGRTRTDENGEFVMDVDKKYPTIDFRYS
                     GNKTCEVALELNQARGAVWVGDVVCSGLSSWAAVTQTGEENES"
     gene            10197..11840
                     /gene="ecpD"
                     /locus_tag="IRB70_002292"
     CDS             10197..11840
                     /gene="ecpD"
                     /locus_tag="IRB70_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial adhesin EcpD"
                     /protein_id="HBC0632201.1"
                     /translation="MRVNLLIAMIIFALIWPATALRAAVSKTTWADAPAREFVFVENN
                     SDDNFFVTPGGALDPRLTGANRWTGLKYNGSGTIYQQSLGYIDNGYNTGLYTNWKFDM
                     WLENSPVSSPLTGLRCINWYAGCNMTTSLILPQTTDASGFYGATVTSGGAKWMHGMLS
                     DAFYQYLQQMPVGSSFTMTINACQTSVNYDASSGARCKDQASGNWYVRNVTHTKAANL
                     RLINTHSLAEVFINSDGVPNLGEGNADCRTQTIGSRSGLSCKMVNYTLQTNGLSNTSI
                     HIFPAIANSSLASAVGAYDMQFSLNGSSWKPVSNTAYYYTFNEMKSADSIYVFFSSNF
                     FKQMVNLGISDINTKDLFNFRFQNTTSPESGWYEFSTSNTLIIKPRDFSISIISDEYT
                     QTPSREGYVGSGESALDFGYIVTTSGKTAADEVLIKVTGPAQVIGGRSYCVFSSDDGK
                     AKVPFPATLSFITRNGATKTYDAGCDDSWRDMTDALWLTTPWTDISGEVGQMDKTTVK
                     FSIPMDNAISLRTVDDNGWFGEVSASGEIHVQATWRNIN"
     gene            11809..12519
                     /gene="ecpE"
                     /locus_tag="IRB70_002293"
     CDS             11809..12519
                     /gene="ecpE"
                     /locus_tag="IRB70_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone EcpE"
                     /protein_id="HBC0632202.1"
                     /translation="MFRRRGVTLTKALLTVVCMLAAPLTQAISVGNLTFSLPSETDFV
                     SKRVVNNNKSARIYRIAISAIDSPGSSELRTRPVDGELLFAPRQLALQAGESEYFKFY
                     YHGPQDNRERYYRVSFREVPTRNQTRRSPTGGEVSTEPVVVMDTILVVRPRQVQFKWS
                     FDQVTGTVSNTGNTWFKLLIKPGCDSTEEEGDAWYLRPGDVVHQPELRQPGNHYLVYN
                     DKFIKISDSCPAKPPSAD"
     gene            12832..13161
                     /locus_tag="IRB70_002294"
     CDS             12832..13161
                     /locus_tag="IRB70_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBC0632203.1"
                     /translation="MSNLNPCMTCGACCAFFRVSFYWAEADDAGGTIPARLTEQISPF
                     HRCMSGTNQKNPRCIALAGTPGKNACCTIYKNRSSTCREFAMSGENGVVNEACNRARA
                     KYGLTPL"
     gene            complement(13411..14025)
                     /locus_tag="IRB70_002295"
     CDS             complement(13411..14025)
                     /locus_tag="IRB70_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YagU family protein"
                     /protein_id="HBC0632204.1"
                     /translation="MNIFEQTPPNRRRYGLAAFIGLIAGVVSAFVKWGAEVPLPPRSP
                     VDMFNAACGPESLIRAAGQIDCSRNFLNPPYIFLRDWLGLTDPNAAVYTFAGHVFNWV
                     GVTHIIFSIVFAVGYCVVAEVFPKIKLWQGLLAGALAQLFVHMISFPLMGLTPPLFDL
                     PWYENVSEIFGHLVWFWSIEIIRRDLRNRITHEPDPEIPLGSNR"
     gene            complement(14623..14698)
                     /locus_tag="IRB70_002296"
     tRNA            complement(14623..14698)
                     /locus_tag="IRB70_002296"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(14663..14665),aa:Thr,seq:cgt)
     gene            complement(14813..16066)
                     /gene="proA"
                     /locus_tag="IRB70_002297"
     CDS             complement(14813..16066)
                     /gene="proA"
                     /locus_tag="IRB70_002297"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBC0632205.1"
                     /translation="MLEQMGIAAKQASYKLAQLSSREKNRVLEKIADELEAQSEIILN
                     ANAQDVADARANGLSEAMLDRLALTPARLKGIADDVRQVCNLADPVGRVIDGGVLDSG
                     LRLERRRVPLGVIGVIYEARPNVTVDVASLCLKTGNAVILRGGKETCRTNAATVAVIQ
                     DALKSCGLPAGAVQAIDNPDRALVSEMLRMDKYIDMLIPRGGAGLHKLCREQSTIPVI
                     TGGIGVCHIYVDESAEIAEALKVIVNAKTQRPSTCNTVETLLVNKNIADSFLPALSKQ
                     MAESGVTLHADAAALAQLQAGPAKVVAVKAEEYDDEFLSLDLNVKIVSDLDDAIAHIR
                     EHGTQHSDAILTRDMRNAQRFVNEVDSSAVYVNASTRFTDGGQFGLGAEVAVSTQKLH
                     ARGPMGLEALTTYKWIGIGDYTIRA"
     gene            complement(16078..17181)
                     /gene="proB"
                     /locus_tag="IRB70_002298"
     CDS             complement(16078..17181)
                     /gene="proB"
                     /locus_tag="IRB70_002298"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBC0632206.1"
                     /translation="MSDSQTLVVKLGTSVLTGGSRRLNRAHIVELVRQCAQLHAAGHR
                     IVIVTSGAIAAGREHLGYPELPATIASKQLLAAVGQSRLIQLWEQLFSIYGIHVGQML
                     LTRADMEDRERFLNARDTMRALLDNNIVPVINENDAVATAEIKVGDNDNLSALAAILA
                     GADKLLLLTDQKGLYTADPRSNPQAELIKDVYGIDDALRAIAGDSVSGLGTGGMSTKL
                     QAADVACRAGIDTIIAAGSKPGVIGDVMEGISVGTLFHAQATPLENRKRWIFGAPPAG
                     EITVDEGATAAILERGSSLLPKGIKSVTGNFSRGEVIRICNLEGRDIAHGVSRYNSDA
                     LRRIAGHHSQEIDAILGYEYGPVAVHRDDMITR"
     gene            17469..18524
                     /gene="phoE"
                     /locus_tag="IRB70_002299"
     CDS             17469..18524
                     /gene="phoE"
                     /locus_tag="IRB70_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoporin PhoE"
                     /protein_id="HBC0632207.1"
                     /translation="MKKSTLALVVMGIVASASVKAAEIYNKDGNKLDVYGKVKAMHYM
                     SDNDSKDGDQSYIRFGFKGETQINDQLTGYGRWEAEFAGNKAESDTAQQKTRLAFAGL
                     KYKDLGSFDYGRNLGALYDVEAWTDMFPEFGGDSSAQTDNFMTKRASGLATYRNTDFF
                     GVIDGLNLTLQYQGKNENRDVKKQNGDGFGTSLTYDFGGSDFAISGAYTNSDRTNEQN
                     LQSRGTGKRAEAWATGLKYDANNIYLATFYSETRKMTPITGGFANKTQNFEAVAQYQF
                     DFGLRPSLGYVLSKGKDIEGIGDEDLVNYIDVGATYYFNKNMSAFVDYKINQLDSDNK
                     LNINNDDIVAVGMTYQF"
     gene            complement(18563..18964)
                     /gene="crl"
                     /locus_tag="IRB70_002300"
     CDS             complement(18563..18964)
                     /gene="crl"
                     /locus_tag="IRB70_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma factor-binding protein Crl"
                     /protein_id="HBC0632208.1"
                     /translation="MTLPSGHPKSRLIKKFTALGPYIREGKCEDNRFFFDCLAVCVNV
                     KPAPEVREFWGWWMELEAQESRFTYSYQFGLFDKAGDWTSVPVKDTEVVERLEHTLRE
                     FHEKLRELLATLNLKLEPADDFRDEPVKLTA"
     gene            complement(19022..20266)
                     /gene="frsA"
                     /locus_tag="IRB70_002301"
     CDS             complement(19022..20266)
                     /gene="frsA"
                     /locus_tag="IRB70_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase FrsA"
                     /protein_id="HBC0632209.1"
                     /translation="MTQANLSETLFKPRFKHPETSTLVRRFNHGAQPPVQSALDGKTI
                     PHWYRMINRLMWIWRGIDPREILDVQARIVMSDAERTDDDLYDTVIGYRGGNWIYEWA
                     TQAMVWQQKACAEEDPQLSGRHWLHAATLYNIAAYPHLKGDDLAEQAQALSNRAYEEA
                     AQRLPGTMRQMEFTVPGGAPITGFLHMPKGDGPFPTVLMCGGLDAMQTDYYSLYERYF
                     APRGIAMLTIDMPSVGFSSKWKLTQDSSLLHQHVLKALPNVPWVDHTRVAAFGFRFGA
                     NVAVRLAYLESPRLKAVACLGPVVHTLLSDFKCQQQVPEMYLDVLASRLGMHDASDEA
                     LRVELNRYSLKVQGLLGRRCPTPMLSGYWKNDPFSPEEDSRLITSSSADGKLLEIPFN
                     PVYRNFDKGLQEITDWIEKRLC"
     gene            complement(20358..20816)
                     /gene="gpt"
                     /locus_tag="IRB70_002302"
     CDS             complement(20358..20816)
                     /gene="gpt"
                     /locus_tag="IRB70_002302"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBC0632210.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMGVVFVPPISGR"
     gene            21077..22534
                     /gene="pepD"
                     /locus_tag="IRB70_002303"
     CDS             21077..22534
                     /gene="pepD"
                     /locus_tag="IRB70_002303"
                     /EC_number="3.4.13.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosol nonspecific dipeptidase"
                     /protein_id="HBC0632211.1"
                     /translation="MSELSQLSPQPLWDIFAKICSIPHPSYHEEQLAEYIVGWAKEKG
                     FHVERDQVGNILIRKPATAGMENRKPVVLQAHLDMVPQKNNDTVHDFTKDPIQPYIDG
                     EWVKARGTTLGADNGIGMASALAVLADENVVHGPLEVLLTMTEEAGMDGAFGLQSNWL
                     QADILINTDSEEEGEIYMGCAGGIDFTSNLHLDREAVPAGFETFKLTLKGLKGGHSGG
                     EIHVGLGNANKLLVRFLAGHAEELDLRLIDFNGGTLRNAIPREAFATIAVAADKVDTL
                     KSLVNTYQEILKNELAEKEKNLALLLDSVANDKAALIAKSRDTFIRLLNATPNGVIRN
                     SDVAKGVVETSLNVGVVTMTDNNVEIHCLIRSLIDSGKDYVVSMLDSLGKLAGAKTEA
                     KGAYPGWQPDANSPVMHLVRETYQRLFNKTPNIQIIHAGLECGLFKKPYPEMDMVSIG
                     PTITGPHSPDEQVHIESVGHYWTLLTELLKEIPAK"
     gene            22543..22824
                     /locus_tag="IRB70_002304"
     CDS             22543..22824
                     /locus_tag="IRB70_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000106438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632212.1"
                     /translation="MSTPAGVDFCLKPMAIYIEITKHYETHEKVAYLYSCDHISWGEF
                     LITKESFALESVKELKGEKQNFYMFRAWGKVRKTYLATGEFPQETCYAA"
     gene            complement(22841..23350)
                     /locus_tag="IRB70_002305"
     CDS             complement(22841..23350)
                     /locus_tag="IRB70_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001361775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBC0632213.1"
                     /translation="MFIGHLPAGYLITCTLVKRLPLIARHARWAMVIGLVGAIAPDFD
                     LFWCYLVDNGQRHHHLYPSHWPLLWFALLAATLVWAAIAKNKLPAWLGVVFCLNGIVH
                     LLLDTLVGDIWWLMPFVNQPFALFHITAVHHPWWLNFLLHWSFLLELALVVAAIAMWY
                     RRNAKMVNA"
     gene            complement(23412..24026)
                     /locus_tag="IRB70_002306"
     CDS             complement(23412..24026)
                     /locus_tag="IRB70_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000602107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor H"
                     /protein_id="HBC0632214.1"
                     /translation="MILLQLSSAQGPEECCLAVKKALDRLIKEATRQDVAVTVLETET
                     GRYSDTLRSALISLDGDNAWALSESWCGTIQWICPSPYRPHHGRKNWFLGIGRFTADE
                     QEQSDAIRYETLRSSGPGGQHVNKTDSAVRATHLASGISVKVQSERSQHANKRLARLL
                     IAWKLEQQQQENSAALKSQRRMFHHQIERGNPRRIFTGMAFVAV"
     gene            complement(24023..25162)
                     /locus_tag="IRB70_002307"
     CDS             complement(24023..25162)
                     /locus_tag="IRB70_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000521550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA ligase RtcB family protein"
                     /protein_id="HBC0632215.1"
                     /translation="MGKYIRPLSDAVFTIASDDLWIESLAIQQLHTTANLPNMQRVVG
                     MPDLHPGRGYPIGAAFFSVGRFYPALVGNDIGCGMALWQTDIFARKYNADKFEKRLSA
                     LDDVAEESWLEENLPSALAQHPWRSSLGSIGGGNHFAELQQVDQIIDAELFALTGLDA
                     QHLQLLVHSGSRGLGQSILQRHIASFSHHGLPEGSDDALRYIAEHDDALAFARINRQM
                     IALRIMQQVKATGSPVLDVAHNFVSACQIGDQQGWLHRKGATPDDNGLVIIPGSRGDY
                     SWLVKPVANEKTLHSLAHGAGRKWGRTECKGRLAAKYTATQLSRTELGSRVICRDKQL
                     IFEEAPQAYKSAESVVQCLVQAGLIIPVARLRPVLTLKNNGGKKG"
     gene            complement(25353..25805)
                     /locus_tag="IRB70_002308"
     CDS             complement(25353..25805)
                     /locus_tag="IRB70_002308"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBC0632216.1"
                     /translation="MNNIQIRNYQPGDFQQLCAIFLRAVTMTASQHYSPQQIAAWAQI
                     DESRWKEKLAKSQVRVAVINAQPVGFITRIEHYIDMLFVEPEYTRRGVASALLKPLIK
                     SESELTVDASITAKPFFERYGFQTVKQQCVECRGEWFTNFYMRYKPQH"
     gene            complement(25815..26213)
                     /gene="yafO"
                     /locus_tag="IRB70_002309"
     CDS             complement(25815..26213)
                     /gene="yafO"
                     /locus_tag="IRB70_002309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafO"
                     /protein_id="HBC0632217.1"
                     /translation="MRVFKTKLIRLQLTAEELDALTADFISYKRDGVLPDIFGRDALY
                     DDSFTWPLIKFERVAHIHLANVNNPFPPQLRQFSRTNDEAHLVYCQGAFDEQAWLLIA
                     ILKPEPHKLARDNNQMHKIGKMAEAFRMRF"
     gene            complement(26216..26509)
                     /gene="yafN"
                     /locus_tag="IRB70_002310"
     CDS             complement(26216..26509)
                     /gene="yafN"
                     /locus_tag="IRB70_002310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system antitoxin YafN"
                     /protein_id="HBC0632218.1"
                     /translation="MHRILAEKSVNITELRKNPAKYFIDQPVAVLSNNRPAGYLLSAS
                     AFEALMDMLAEQEEKKLVKARFRPSAARLEEITRRAEQYLNDMTDDDFNDFKE"
     gene            complement(26561..27616)
                     /gene="dinB"
                     /locus_tag="IRB70_002311"
     CDS             complement(26561..27616)
                     /gene="dinB"
                     /locus_tag="IRB70_002311"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBC0632219.1"
                     /translation="MRKIIHVDMDCFFAAVEMRDNPALRDIPIAIGGSRERRGVISTA
                     NYPARKFGVRSAMPTGMALKLCPHLTLLPGRFDAYKEASNHIREIFSRYTSRIEPLSL
                     DEAYLDVTDSVHCHGSATLIAQEIRQTIFNELQLTASAGVAPVKFLAKIASDMNKPNG
                     QFVITPAEVPAFLQTLPLAKIPGVGKVSAAKLEAMGLRTCGDVQKCDLVTLLKRFGKF
                     GRILWERSQGIDERDVNSERLRKSVGVERTMAEDIHHWSECEAIIELLYPELERRLAK
                     VKPDLLIARQGVKLKFDDFQQTTQEHVWPRLNKADLIATARKTWDERRGGRGVRLVGL
                     HVTLLDPQMERQLVLGL"
     gene            complement(27687..28472)
                     /gene="lafU"
                     /locus_tag="IRB70_002312"
     CDS             complement(27687..28472)
                     /gene="lafU"
                     /locus_tag="IRB70_002312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706230.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative lateral flagellar export/assembly
                     protein LafU"
                     /protein_id="HBC0632220.1"
                     /translation="MTTIKLIVNSVSKSERESIIAALHGQSIFNGGGLSPLNKISPSH
                     PSKPATVAVPEETEKKARDVNEKTALLKKKSATELGELATSINTIARDAHMEANLEME
                     IVPQGLRVLIKDDQNRNMFERGSAQIMPFFKTLLVELAPVFDSLDNKIIITGHTDAMA
                     YKNNIYNNWNLSGDRALSARRALEEAGMPEDKVMQVSAMADQMLLDAKNPQSAGNRRI
                     EIMVLTKSASDTLYQYFGQHGDKVVQPLVQKLDKQQVLSQRTR"
     gene            28444..30156
                     /locus_tag="IRB70_002313"
                     /pseudo
     CDS             28444..30156
                     /locus_tag="IRB70_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001140831.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
     gene            complement(30254..31027)
                     /locus_tag="IRB70_002314"
     CDS             complement(30254..31027)
                     /locus_tag="IRB70_002314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308281.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBC0632221.1"
                     /translation="MHDQPLLRMSLPSIPSFVLSGLLLLCLPFSSFASATTSHISFSY
                     AARQRMQNRARLLKQYQTHLKKQASYIVEGNAESRRALRQHNREQIKQHPEWFPAPLK
                     ASDRRWQALAENNHFLSSDHLHNITEVAIHRLEQQLGKPYVWGGTRPDKGFDCSGLVF
                     YAYNKILEAKLPRTANEMYHYHRATIVANNDLRRGDLLFFHIHSREIADHMGVYLGDG
                     QFIESPRTGETIRISRLAEPFWQDHFLGARRILTEETIL"
     gene            31213..31473
                     /gene="dinJ"
                     /locus_tag="IRB70_002315"
     CDS             31213..31473
                     /gene="dinJ"
                     /locus_tag="IRB70_002315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin DinJ"
                     /protein_id="HBC0632222.1"
                     /translation="MAANAFVRARIDEDLKNQAADVLAGMGLTISDLVRITLTKVARE
                     KALPFDLREPNQLTIQSIKNSEAGVGIHKAKDADDLFDKLGI"
     gene            31476..31753
                     /gene="yafQ"
                     /locus_tag="IRB70_002316"
                     /pseudo
     CDS             31476..31753
                     /gene="yafQ"
                     /locus_tag="IRB70_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414760.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YafQ"
     gene            31909..32649
                     /locus_tag="IRB70_002317"
     CDS             31909..32649
                     /locus_tag="IRB70_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein L,D-transpeptidase"
                     /protein_id="HBC0632223.1"
                     /translation="MRKIALILAMLLIPCVSFAGLLGSSSSTTPVSKEYKQQLMGSPV
                     YIQIFKEERTLDLYVKMGEQYQLLDSYKICKYSGGLGPKQRQGDFKSPEGFYSVQRNQ
                     LKPDSRYYKAINIGFPNAYDRAHGYEGKYLMIHGDCVSIGCYAMTNQGIDEIFQFVTG
                     ALVFGQPSVQVSIYPFRMTDANMKRHKYSNFKDFWEQLKPGYDYFEQTRKPPTVSVVN
                     GRYVVSKPLSHEVVQPQLASNYTLPEAK"
     gene            complement(32620..33387)
                     /locus_tag="IRB70_002318"
     CDS             complement(32620..33387)
                     /locus_tag="IRB70_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II glutamine amidotransferase"
                     /protein_id="HBC0632224.1"
                     /translation="MCELLGMSANVPTDICFSFTGLVQRGGGTGPHKDGWGITFYEGK
                     GCRTFKDPQPSFNSPIAKLVQDYPIKSCSVVAHIRQANRGEVALENTHPFTRELWGRN
                     WTYAHNGQLTGYKSLETGNFRPVGETDSEKAFCWLLHKLTQRYPRTPGNMAAVFKYIA
                     SLADELRQKGVFNMLLSDGRYVMAYCSTNLHWITRRAPFGVATLLDQDVEIDFSSQTT
                     PNDVVTVIATQPLTGNETWQKIMPGEWRLFCLGERVV"
     gene            complement(33503..34081)
                     /gene="lpcA"
                     /locus_tag="IRB70_002319"
     CDS             complement(33503..34081)
                     /gene="lpcA"
                     /locus_tag="IRB70_002319"
                     /EC_number="5.3.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-sedoheptulose 7-phosphate isomerase"
                     /protein_id="HBC0632225.1"
                     /translation="MYQDLIRNELNEAAETLANFLKDDANIHAIQRAAVLLADSFKGG
                     GKVLSCGNGGSHCDAMHFAEELTGRYRENRPGYPAIAISDVSHISCVGNDFGFNDIFS
                     RYVEAVGREGDVLLGISTSGNSANVIKAIAAAREKGMKVITLTGKDGGKMAGTADIEI
                     RVPHFGYADRIQEIHIKVIHILIQLIEKEMVK"
     gene            34321..36765
                     /gene="fadE"
                     /locus_tag="IRB70_002320"
     CDS             34321..36765
                     /gene="fadE"
                     /locus_tag="IRB70_002320"
                     /EC_number="1.3.8.7"
                     /EC_number="1.3.8.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase FadE"
                     /protein_id="HBC0632226.1"
                     /translation="MMILSILATVVLLGALFYHRVSLFISSLILLAWTAALGVAGLWS
                     AWVLVPLAIILVPFNFAPMRKSMISAPVFRGFRKVMPPMSRTEKEAIDAGTTWWEGDL
                     FQGKPDWKKLHNYPQPRLTAEEQAFLDGPVEEACRMANDFQITHELADLPPELWAYLK
                     EHRFFAMIIKKEYGGLEFSAYAQSRVLQKLSGVSGILAITVGVPNSLGPGELLQHYGT
                     DEQKDHYLPRLARGQEIPCFALTSPEAGSDAGAIPDTGIVCMGEWQGQQVLGMRLTWN
                     KRYITLAPIATVLGLAFKLSDPEKLLGGAEDLGITCALIPTTTPGVEIGRRHFPLNVP
                     FQNGPTRGKDVFVPIDYIIGGPKMAGQGWRMLVECLSVGRGITLPSNSTGGVKSVALA
                     TGAYAHIRRQFKISIGKMEGIEEPLARIAGNAYVMDAAASLITYGIMLGEKPAVLSAI
                     VKYHCTHRGQQSIIDAMDITGGKGIMLGQSNFLARAYQGAPIAITVEGANILTRSMMI
                     FGQGAIRCHPYVLEEMEAAKNNDVNAFDKLLFKHIGHVGSNKVRSFWLGLTRGLTSST
                     PTGDATKRYYQHLNRLSANLALLSDVSMAVLGGSLKRRERISARLGDILSQLYLASAV
                     LKRYDDEGRNEADLPLVHWGVQDALYQAEQAMDDLLQNFPNRVVAGLLNVVIFPTGRH
                     YLAPSDKLDHKVAKILQVPNATRSRIGRGQYLTPSEHNPVGLLEEALVDVIAADPIHQ
                     RICKELGKNLPFTRLDELAHNALAKGLIDKDEAAILVKAEESRLRSINVDDFDPEELA
                     TKPVKLPEKVRKVEAA"
     gene            complement(36808..37254)
                     /gene="ivy"
                     /locus_tag="IRB70_002321"
     CDS             complement(36808..37254)
                     /gene="ivy"
                     /locus_tag="IRB70_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308274.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ivy family C-type lysozyme inhibitor"
                     /protein_id="HBC0632227.1"
                     /translation="MFKAITTVAALVIATSAMAQDDLTISSLAKGETTKAAFNQMVQG
                     HKLPAWVMKGGTYTPAQTVTLGDETYQVMSACKPHDCGSQRIAVMWSEKSNQMTGLFS
                     TIDEKTSQEKLTWLNVNDALSIDGKTVLFAALTGSLENHPDGFNFK"
     gene            37435..38205
                     /gene="yafV"
                     /locus_tag="IRB70_002322"
     CDS             37435..38205
                     /gene="yafV"
                     /locus_tag="IRB70_002322"
                     /EC_number="3.5.1.111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutaramate amidase"
                     /protein_id="HBC0632228.1"
                     /translation="MPGLKITLLQQPLVWMDGPANLRHFDRQLEGITGRDVIVLPEMF
                     TSGFAMEAAASSLAQNDVVNWMTAKAQQCNALIAGSVALQTESGSVNRFLLVEPGGTV
                     HFYDKRHLFRMADEHLHYKAGNARVIVEWRGWRILPLVCYDLRFPVWSRNLNDYDLAL
                     YVANWPAPRSLHWQALLTARAIENQAYVAGCNRVGSDGNGCHYRGDSRVINPQGEIIA
                     TADAHQATRIDAELSMVALREYREKFPAWRDADEFRLW"
     gene            complement(38258..38359)
                     /locus_tag="IRB70_002323"
                     /pseudo
     CDS             complement(38258..38359)
                     /locus_tag="IRB70_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(38482..>38630)
                     /locus_tag="IRB70_002324"
     CDS             complement(38482..>38630)
                     /locus_tag="IRB70_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0632229.1"
                     /translation="FPTDESVRKVIWLATEAAATKWTMPIINWRLAMSRFIIEYGDRL
                     SDHL"
BASE COUNT         9983 a         9690 c         9486 g         9471 t
ORIGIN      
        1 aaaatccagg aaatgaaacg gcccaatcct caagaatcgg ctgtaacttg cccgcattga
       61 tatgctcagc gattgcaaaa tccagatgtt gaatgatacc cgttccattc agcgccattc
      121 gtatcatgct ttcgtcatca ttagaaatat acttacctga cacctctatt tcgaactctt
      181 cattaccccc cacaacattc gaaaactccc atgctgagag tgcaccgcta cttttatgcc
      241 gcaaccgaag acaattatgg ttactcaatt cctgaggagt ttcaggaata ccgtgttctt
      301 ttaaataatc tggcgatgcc acagtaacca gtttaataag cggagaaaca ggaacggcag
      361 tcatatgctc atccagtcct tgctcaagac gtatgcccac atcacagccg tccgcaataa
      421 tgttagataa accgtcatcc ataatgagtt ctatctttgt tttggggtaa cgagtaagaa
      481 actcgccaat atgaggctca acaagcatcc gtgctgcaac acgggaggaa tttattctca
      541 acaggcctgt aggttcaagt tgggtatcac caacatcttt caaagcatca tcaatttgcc
      601 ccaaagccga caccagcact tcatacagac gctgtccttc ctcagtaagc gacatattgc
      661 gggtcgtacg gtatatcagc ttggtgttaa gacgttcctc aagagatttt aaattctggg
      721 acaatgcggc ccgcgtaata cccatttcag aagcggctct ggaaaaactg ccggcacgaa
      781 caataagcgc aaaccaggca agagaaggca aaattgaagg ctctattttc atcattgtaa
      841 accttaactt aacactgtga tagatattag accattgatg ataaccaata caagtcatac
      901 tattacgccg ttctcgatat gaacacgaat gccagttgcg gataatagaa atgatattta
      961 aatctgttta ggcaaatccc cggagcttga aatgaaaact gtttcgataa aacatactta
     1021 ctgggatata gctgctgata tctatttccc tgacgatttt aatagtgaaa aaaagtatcc
     1081 tgccattatc agcgcccatc caattggaag ctgcaaagaa cagacatcgg gtagtgtgta
     1141 tggtgccgcc ctggcaaaag ctggctttat cgtcattgct tttgatgcca gttttcaggg
     1201 aagcagcggt ggagaaccgc gttatctgga agatccaaca atgcgagtaa aagacttcag
     1261 cattgtcgtt gattatctta ccagcttacc ttacgttgat gccgggcgta ttggtgtact
     1321 gggtatttgt ggtggaggtg gatatgccat taatgccgca atgacagaac gtcgaattaa
     1381 agctattggt actgtcacgg gtgcaaacta cgggcgtctt atgcgtgagg gatttacagc
     1441 gtttaatcct atcggagcac tcgaagcaat ggcgcaacaa agaacagacg aagctaacgg
     1501 cgcaaaactt cgcgtagatg atttgctccc ttcttctccg gaagcagctc ttgaagcggg
     1561 attaacagaa atagaccttt ttgaagcaac agaatattat cgttcgccac gaggctgtgc
     1621 acctaatggg gtaaatcgtt cgctattctc acatcagact gttgccgtgg gttgggatgc
     1681 atttcatctt gcagaagtcc tgttaactca accaataatg gttgtggtgg gcgatagagt
     1741 gggcgcattt ggtgcctacc gtgacggctg cgaaattatt ggccgcgctg cctcaaaaca
     1801 taaagagctg gtcgtggttg aaggttattc acattacgac ctgtatgata agccagaacc
     1861 tgtgaaacag gcactcgaca aattaattcc tttttataaa acacatttgt aataatctta
     1921 cagggagatt ccttatctcc ctgacattta tcctttattg actacacaac aataataaaa
     1981 ttactcaaaa agaaatttca ttaaagaaac aaaaaagcag caactcaatt attaagatta
     2041 ttagaaaccc tttgaaggaa ttataaataa agccataaat cttggttcca aagctggcaa
     2101 caactaacct gttaaaacat acgcatcaaa atcagataaa catttgaggt attgttatga
     2161 caaataaaca cccatcattg ttttctcctt ttatgctgac agaaaaaata aagctacgta
     2221 atcgtatcgt tatggctcct atgacgacct ggtcagcgaa tcctgatgga accatctctg
     2281 agcaagaact cgaattttat aaacgtcgct cacaaaatgt tggtttagta ataacaggat
     2341 gcacctatgt cacgccaagc ggcattgggt ttactcatga atttgccgcg tatgacgacc
     2401 gtttcattaa cagccttgaa aagttagcag ctgcagccaa aagtggcggt gctccggcta
     2461 ttttgcagat tttccacgcc ggtaataaag ccatcccgga gcttgtgcca aataacgatg
     2521 ttattagtgc cagcgcatca agcgtaaaat ctggtgactt tatgaagaga gtggtacaaa
     2581 gcagggaaat gactgaaaac gaaattcagg aaaccattag agcattcgga gatgtcacaa
     2641 aaagggcgat taaagcaggt tttgatggcg ttgaacttca tggtgcgcac ggattccttc
     2701 tgcagaattt cttctcccct ctatttaacc agcgtaatga ccgatgggga ggagatctcg
     2761 aaggacgtat gcgcttcccg ctggccgtat tacaggaagt aaaaaatgta gtctatgaat
     2821 atgcgacaaa gccctttgcc atcggttaca gaatatctcc tgaagaatct gcaacagggg
     2881 ggctgcggat agaggatact tataaactcc ttgatcggct catttcatcc ggtatttcgt
     2941 atatacatac ctcactggtc agtattaacg atagctaccc tgttgagtcg ccaaatggcc
     3001 cccgaactat tgaattgatt ttaaatcata ttgcaggcag agtgccggta atcgctgcag
     3061 gtaaaatacg cacaccgtct caggctcaag aagcaatttc cactggcctg ccacttgttg
     3121 cgatcggtaa agggctggtg ataaatccag aatgggtgac tttagctgaa tcaggtagag
     3181 accatgaaat tcaaacaacc cttaatccac aacttgttca tgaattaacc attccggata
     3241 aactatggga tcaaattcag acatcgaaag gaactggctg gtttccgtta atggattaaa
     3301 tatctattac tctcccgaga gtaaaactat caaaccaatg agtaaccgat acagcctcac
     3361 aaattctttc agataattaa cccgtcactg cggcacgttc tctcgtaagg cgtgcctgca
     3421 gtgtaatcca gtatgtatcc ggcatagttg acggtttaat agaactcaat tcctctccct
     3481 ggttacctac aacgatatct tgtataacac cccaggagat acgacattat gatgagatgc
     3541 gatatgctcc tcagcgccaa tcaacgccag ggctgggcca gtcttgagat cagactcatt
     3601 cccgaaactg acttcaggcg acatttatca atgacgttgg tgcaataaaa gatagccgat
     3661 gtaatacatc tattcaaatt tgtgatacat gtcaaaaaat tggttgacca aactcgttat
     3721 ttatataagg gcacttacga agtgcactct tttttaaagc gaggaagtac caatgaaaga
     3781 gaataaagta cagcaaatca gtcataaact gattaatatc gttgtttttg tcgcaattgt
     3841 agaatacgcc tatttatttc tccatttcta ttaataacgg caataaactg ttcacttcag
     3901 tgatatttaa aatatgcatc ctctcccttt tttgtaagta attattatat ccgtgggaga
     3961 ggaatatacg ctgtcaggta atcaatcaaa ctgcgataaa tcatcggcca gtaaagtgga
     4021 gatagcctcc attctcgaaa aatccatact ctcagcgaaa ccatcatcaa tcactcatcc
     4081 aggcgtttat gggagcgtcg ccaatggctg ctaacaatgt cagacttccc cgttgcggaa
     4141 attccacatc ccacaaatag tcacagggat tgggtgttga aatgatccgg atgagcatgt
     4201 atctttatgg ttatgttata acataacagg taaaaatgat gaagcccaat atccatcctg
     4261 agtatcgtac tgtggtgttc cacgacacca gtgttgatga gtactttaaa atcggctcga
     4321 ctatcaaaac agaccgtgag attgagctgg atggcgtaac gtatccgtac gtgacaattg
     4381 atgtctcttc taaatcgcac ccgttctata cagggaagct gagaacagtg gcatcagaag
     4441 gaaatgttgc acgattcacc caacgttttg gtcgttttgt tagcacgaaa aagggggcat
     4501 gatgaaagtc cttaactctc tgcgtaccgc aaaagaacgc catccagact gtcagattgt
     4561 gaagcgaaaa ggacggctgt atgtgatttg taaatctaat ccacgtttta aggccgttca
     4621 gggtcgtaag aaaaaacgtt gatttaaaat tcgacgaatt aacgatattt gtctgattaa
     4681 taatcagacc ggattaatgt tggtgtattt attacaccag cattaatttt cctggggatg
     4741 tatcttcctg ttcatttaag gtcaactgcc tgacgtttct ctccgaatat tccattatat
     4801 taatgttgac ttgttgacca gcttcgccct gtatgctggc atcaactcta ttttagactg
     4861 aacacgtcac tcagtttcct ccctttgcga cgcagcctgc atttacactc aaactgttaa
     4921 gatgataaat gtggtaaatc tgttggtact gacataaaaa cgtttacgcc acaggaacgg
     4981 ccagatccat cggtaacccc atcgccgacg ttcgagtgcc agttagagta acgcgcacag
     5041 atgactgaat gcagtgccct ggcaaagagg ccatcgttcc tgtgacaact ggcagtcttc
     5101 gtttaacttc acttaatttg gctcttaggg ggcttaccgg acagatgaag tacttacacc
     5161 tgtttaattt tccatcactt attggaatga acacccataa ccattttgtg cggcatgtta
     5221 atccattaaa acaccttact gattggcaaa tcatctttaa ttatgactta tgatagtttt
     5281 atattccatt tcttatcatt taaacttgtt tttttactag tccattacac aacacattaa
     5341 gactattcct aacacctcag ggcaaagttc ctggctaata taaaatgcaa gtaagaattg
     5401 aacgttatat tgccaataac cttatgaaac tgaatgtctt tttcttctta tcaaaaaagc
     5461 aatattttca ttttttgtaa atattgactt aaccatggaa ttcattttct gttcacatat
     5521 tgacactcat caggaaaaaa acataaattt aaacctaatc gaaataatta aaacttaatc
     5581 tcgtttaacc tatattgata tgtgctacgt atcttattta cttccgattt actaaagaaa
     5641 ctgaatgtac ctgtaaaaat tacaggtttg gaaagtagtg acatggcaaa atgattacag
     5701 cagggactat gaggttaaaa accatatgga atgtcaaaac cgttctgata aatacatctg
     5761 gtctccccat gacgcctact tctataaagg actatctgaa ctgattgtgg atatcgacag
     5821 attaatttat ctatcgctgg agaaaatcag aaaagatttc gtgtttatca atctcaatac
     5881 ggattcttta actgagttta taaaccgtga taatgagtgg ttatccgcgg taaaggggaa
     5941 acaggtcgta ttgattgcgg ccagaaagtc agaagcctta gcaaattatt ggtattacaa
     6001 cagcaatatt aggggcgtgg tatacgctgg actgagtcgt gatattagaa aagaactggc
     6061 ctatgtgatt aatggcaggt tcctgagaaa agatattaag aaagataaaa tcactgaccg
     6121 ggaaatggaa attatccgca tgacggctca gggaatgctg cctaaatcga ttgccagaat
     6181 tgaaaattgt agtgtaaaga cagtgtatac ccatcggcgt aatgcagagg ccaagctgta
     6241 ctcaaaatta tataagttgg ttcagtaaac tccaggcaag ttagttttaa aaaatgactc
     6301 accgggactt catgtcctca attcaactcg ggaagaaaag caataaaaaa aaaggttctg
     6361 gcaatagctc tggtaacggt gtttaccggt acaggtgtgg cgcaggctgc tgacgtaaca
     6421 gctcaggctg tagcgacctg gtcagcaaca gccaaaaaag acaccaccag taagctggtt
     6481 gtgacgccac tcggtagcct ggcgttccag tatgccgaag gcattaaagg ttttaactca
     6541 cagaaaggtc tatttgacgt ggctatcgag ggtgactcaa cggctaccgc ctttaaactg
     6601 acctcacgtc ttatcaccaa caccttaacc cagttggata cctcaggttc cacactgaat
     6661 gtgggcgtgg attataacgg cgcggcagtc gaaaaaactg gcgataccgt gatgatcgat
     6721 accgccaacg gcgtactggg cggcaacctt agcccgctgg ctaacggtta caatgccagc
     6781 aatcgtacca ccgcacagga tggtttcact ttctccatca tcagcggcac caccaatggt
     6841 accaccgcag taaccgatta cagcactcta ccggaaggca tctggagcgg cgacgttagc
     6901 gtacagttcg acgcgacctg gaccagttaa tctctctgat gtaccagcag gggtagcccc
     6961 cctgctttat tcctggacgg aattgttatg aaaaagcacc ttctgcctct cgctttgctg
     7021 ttatccggaa tatctccggc ccaggcgctg gatgtcggcg atatatcatc gtttatgaac
     7081 agtgacagca gcacgctgag caaaacgatc aaaaacagta ccgacagtgg tcgcctcatc
     7141 aatatccgtc tcgaacggct ctcttcaccg cttgacgacg ggcaggttat ctcaatggac
     7201 aagccggatg agttgctact cactcccgct agcttgctgc tacccgccca agccagcgaa
     7261 gtgatccgct tcttctataa gggaccagca gatgaaaaag agcgctacta ccgcattgtc
     7321 tggtttgatc aggccctcag tgatgcgcag cgcgataatg ccaaccgcag cgctgtggcc
     7381 actgcttccg cccgcatcgg caccattctg gtcgtcgcac cccgccaggc aaactaccac
     7441 tttcagtacg ccaacggctc cctgacaaat acaggaaatg cgacgctgcg gatcctcgcc
     7501 tacggcccct gcctgaaagc cgccaatggt aaagagtgta aagagaatta ctacctgatg
     7561 ccgggcaagt cgcgtcgttt tacccgcgtg gacacggcgg ataacaaagg acgggttgca
     7621 ctttggcagg gtgataagtt cattcccgtg aaatagatag ctgtgcagat ggataacgac
     7681 aatgccttta cgacggttct ccccaggact gaaagcccag tttgccttcg gcatggtctt
     7741 tttgttcgtt cagcccgatg ccagcgctgc tgacataagt gcgcagcaaa taggtggggt
     7801 gattattccg caggccttca gtcaggcgct tcaggacggc atgagcgtcc cgctctatat
     7861 tcatctcgcc ggtagccagg gtcgccagga cgatcagcga atcggcagcg cttttatctg
     7921 gttggatgat ggacagctac gcatccggaa aatacagctg gaagagagtg aagataacgc
     7981 cagtgtcagc gaacaaactc gacagcagct gatggctctg gcgaacgccc cgttcaatga
     8041 ggcccttacc atccccctga ctgacaacgc gcagttggat ctcagcttgc gccaactgct
     8101 gctgcagctg gtggtcaagc gcgaagcgct gggcactgta ctacgctcac gtagcgaaga
     8161 catcgggcag tccagtgtta acaccctcag cagtaatctg agctataact tcggcatcta
     8221 taacaaccag ttgcgtaacg gcgggagcaa cacatccagc tatctgtcgc tgaataacgt
     8281 tactgcactg cgcgaacatc atgtggtgct cgacggctcg ctgtacggga tcggtagcgg
     8341 tcaacaggac agtgaattat ataaagcgat gtatgaacgc gattttgccg gtcaccgatt
     8401 tgccggtgga atgctcgaca cctggaactt gcagtcctta gggccgatga ccgccatttc
     8461 agcagggaag atttacggcc tttcctgggg aaaccaggcc agctccacca tcttcgacag
     8521 cagccagtca gccacgccag tgatcgcctt tttaccggcg gcgggcgaag tacatctcac
     8581 ccgtgatggg cggttactaa gcgttcagaa cttcaccatg ggcaatcatg aagtggatac
     8641 ccggggtcta ccgtacggta tttacgatgt ggaagttgag gtcatcgtta acggtcgcgt
     8701 gattagcaaa cgcactcaac gggtcaataa gctgtttagc cgggggcgcg gcgtcggtgc
     8761 accactggcg tggcagatat ggggcggtag ctttcatatg gatcgctggt cggaaaacgg
     8821 gaaaaagacg cgaccagcta aagagagttg gctggcaggt gcctcgacct ccggctcact
     8881 gagtacgctt agctgggcgg caacgggata tggatacgat aatcaggcgg tgggtgaaac
     8941 ccgtctgacg ctgccgcttg ggggggcgat caacgttaac ctgcaaaaca tgctggccag
     9001 tgacagctca tggagcaaca tcgccagcat cagcgccact ctacctggag gcttcagttc
     9061 gctgtgggtt aaccaggaaa aaacccgcat tggcaatcaa ttgcgacgta gcgatgccga
     9121 caaccgtgca atcggcggca cactcaacct gaactcactg tggtcgaagc tgggtacgtt
     9181 cagcatcagc tacaatgatg accgccgcta caacagccat tattacacgg cagattacta
     9241 tcaaagtgtc tacagcggta cctttggttc gcttggcctg cgggccggta ttcagcgcta
     9301 taacaacggc gacagcagcg ccaatacagg gaaatatatc gctctcgatc tctcgctacc
     9361 actgggcaac tggtttagcg cagggatgac ccatcaaaac ggctacacca tggcaaacct
     9421 gtcagcacgc aaacagtttg atgaaggaac cattcgcact gttggtgcca atctgtcacg
     9481 agccatctcc ggcgataccg gtgatgacaa aaccctcagc ggtggggcgt atgcacagtt
     9541 cgacgctcgt tacgccagcg gaacgctgaa cgtcaatagc gcggcggacg gctacatcaa
     9601 taccaatttg accgccaacg gcagcgtcgg ctggcagggt aaaaacatcg ctgccagcgg
     9661 gcggaccgat ggcaacgctg gggtgatatt cgacactggc ctggagaacg atggtcagat
     9721 cagcgccaaa atcaacgggc ggattttccc gcttaacggc aagcgtaact atctcccgct
     9781 ctctccctat ggaagatatg aggtggagtt gcagaacagc aaaaactcac tcgacagtta
     9841 cgatatcgtc agcggtcgca aaagtcatct gactctctat ccaggcaatg tcgctgtcat
     9901 tgagccagag gtgaagcaga tggttaccgt ctccggtcgt atccgtgcgg aagacggcac
     9961 actgctggct aacgcacgga ttaacaacca tatcggccga acccgaaccg atgaaaacgg
    10021 cgagtttgtc atggacgtgg ataagaaata ccccactatc gattttcgct acagtggcaa
    10081 taaaacctgc gaagtggcac tggaactcaa ccaggcgcgc ggtgccgtct gggtcggtga
    10141 tgtggtctgc agcggcctct catcgtgggc ggcggtgacg cagacaggag aagagaatga
    10201 gagttaacct actgatagcg atgataatct ttgcgctaat ctggcctgca accgcgctca
    10261 gagcggcagt gagcaaaaca acctgggcgg atgctccggc acgcgagttt gtgtttgtcg
    10321 aaaacaactc agacgacaac tttttcgtca ctcctggcgg ggcgctggat ccgcgcctga
    10381 ccggtgccaa ccgctggacc ggtttaaaat acaatggttc aggaaccatc tatcagcaaa
    10441 gcctcggcta cattgataac ggttacaaca ccggccttta taccaactgg aagtttgata
    10501 tgtggctgga aaattcacca gtttcatctc ctttaactgg cttgcgctgc atcaactggt
    10561 acgcagggtg taatatgacc accagtctta tcctgccgca aaccaccgac gccagtggat
    10621 tttatggcgc gacggtgacc agcggcggcg cgaaatggat gcacggcatg ttgtcagacg
    10681 cgttttacca gtatctgcaa caaatgcccg tcggcagcag ctttacaatg accatcaatg
    10741 cctgccagac ctctgtgaac tatgacgcca gcagcggcgc acgctgtaag gatcaggcct
    10801 ccggcaactg gtatgttcgc aacgtcaccc atacgaaagc agcaaatcta cggttgataa
    10861 atacccactc gctggcggaa gtatttatca acagcgacgg agtaccgaat ctgggcgaag
    10921 ggaacgccga ctgccggacg caaaccatcg gcagccgttc aggattaagt tgtaagatgg
    10981 ttaactatac cctgcaaaca aacggactca gcaacacctc aatccatata ttcccggcga
    11041 tcgccaactc gtcgttagcc tcggccgtcg gggcgtacga tatgcagttc agtctgaatg
    11101 gcagttcatg gaaaccggtg agcaatactg cctattacta caccttcaac gagatgaaga
    11161 gcgcagactc gatctatgtt ttcttctcga gcaacttctt taagcagatg gtgaacctcg
    11221 ggatcagcga tatcaatacc aaagatctgt tcaactttcg ctttcagaac accacatcac
    11281 cggagtctgg ctggtatgaa ttttctacct ccaacacgct gattatcaaa ccccgtgatt
    11341 tcagcatcag tattatctcc gatgaatata ctcagacacc gtcgcgggag ggatatgtcg
    11401 gcagcggcga gtcggcactc gatttcggct atatcgtaac caccagcggt aaaacagctg
    11461 ccgacgaagt gctgatcaag gtgaccggac ccgcgcaggt gattggcggg cgctcctatt
    11521 gtgtcttcag ctccgatgac ggtaaggcga aagtaccgtt cccggcgaca ctttccttta
    11581 ttacccgcaa cggagctaca aaaacctacg atgccgggtg cgatgatagc tggcgggata
    11641 tgaccgatgc gctgtggttg accacaccgt ggactgatat ctctggcgaa gtggggcaga
    11701 tggataagac cacagtcaaa ttttcgattc caatggataa cgccatttcg ctgcgtacgg
    11761 tagatgataa cggctggttt ggcgaagtca gcgcttcagg agaaattcat gttcaggcga
    11821 cgtggcgtaa cattaactaa ggccctgctg acagtggtct gtatgctggc ggcacctttg
    11881 acacaggcga tttcggtcgg caatctgaca ttttcgctgc cgtccgagac tgactttgtc
    11941 agcaaacgtg tagtgaataa caacaaaagc gcgcggatat accgtattgc catcagtgct
    12001 atcgatagcc cgggcagcag tgaattgcgc acccgaccgg tggatggtga actgcttttc
    12061 gccccccgcc agctggcgtt gcaggctggt gagagcgagt attttaaatt ttactatcat
    12121 ggtccacagg ataaccgcga gcgctactac cgggtctcat ttcgcgaggt ccccactcgc
    12181 aaccagacaa gacgtagccc aaccggcggc gaggtcagca cagagccggt ggtggtgatg
    12241 gataccattc tggtagtacg accacgtcag gttcagttta aatggtcctt cgatcaggtg
    12301 accggaacgg taagtaacac cggcaacacg tggtttaagc tactgattaa accaggatgt
    12361 gattcgaccg aagaggaagg cgatgcctgg tatctacgtc cgggagacgt ggttcatcag
    12421 cctgagttac gtcagccggg gaatcactat ctggtctata acgacaaatt cattaagatt
    12481 agcgattcct gtccggctaa gcccccttcg gcggactaag acttatccat cagacgaggg
    12541 aagaattcca cctcagagac tcaaaaatcg tttaaatgat gtggaagcga tcgtcaatgt
    12601 cacctgtaac gatgagcttt ctcatatgta caccatagtg ttcaggagac acggaaaggt
    12661 accaggcggc ctgctaacga gtggtttctt cactaattag gacgtaaaat cggtaacggc
    12721 tggaaatcat tcaatactca cactatcgaa agtacaccag ccaaccgcga tacgtccctg
    12781 catacgacgt accgcagttc tctttacgat ttatagctgt actggtgaat tatgagcaat
    12841 ctgaatccat gcatgacgtg tggtgcctgt tgtgcatttt tccgcgtctc tttttactgg
    12901 gccgaagccg acgatgctgg cggtaccatt cccgccaggc tcactgaaca aatatcccct
    12961 tttcaccgat gcatgagcgg taccaatcag aaaaaccccc gatgtattgc ccttgcagga
    13021 acaccgggca aaaatgcctg ctgcacgata tataaaaatc gatcttccac gtgcagagaa
    13081 ttcgccatgt ctggtgagaa cggagtcgtc aatgaggctt gcaatcgtgc aagagctaaa
    13141 tacgggctga caccgttata aatatgcaat aattaattgc actgccccgc cagctataat
    13201 cgcggggctt cgtttttcag ggataacaaa acccgaaact tcttccatct gccagcaaca
    13261 atgcctcttc ctctatagtg ttctccggat ctacagcatc ctgaagtagc gcgatgtact
    13321 cactggctat ctgccatcag aaagttaaaa acaatgtttt taacctataa aaatggcgct
    13381 gtatttgcgc catttttatc attcaatgca ttatctgttt gagcctaaag ggatctcagg
    13441 gtctggctca tgagtaattc tgtttcgtaa atctctgcga ataatttcaa tggaccagaa
    13501 ccagactaaa tgtccaaaaa tttcagaaac attctcatac cacgggagat caaacagagg
    13561 tggcgtcagt cccatgagag ggaatgaaat catatgaaca aaaagttggg ctaaagcacc
    13621 tgccagtaag ccctgccaga gtttaatttt tggaaatact tcagcgacca cacaataacc
    13681 gacagcaaac actatcgaaa agataatgtg cgtaacacca acccagttaa agacatgccc
    13741 ggcaaaggta taaacagccg cattgggatc tgtcagcccc agccagtctc gaagaaaaat
    13801 atacggagga ttgagaaaat tacgggagca atcaatttgc ccagcagccc tgattaatga
    13861 ttccggacca cacgctgcat taaacatatc caccgggcta cgtggcggca atggaacttc
    13921 agccccccac ttcacaaatg cggaaacaac gccagcaatc agcccaatga atgcagcaag
    13981 accataacgt ctgcggttcg gtggagtttg ttcaaatata ttcatattta ccctgtttgt
    14041 ttaattatgt tgtacacctc ttcaggagta ttcataaaac aaggcaaatg taaagaactg
    14101 tattgttttg tataaccaca tggttaccta atcgccaatt aatataagct ccattatttc
    14161 tccatatttt tatgttagaa gtgacaagga gaaatgtaat gtttctctca gagaatataa
    14221 atcattcctt ttgcccacct taatggtggg cttttttatg caaaacctga acaccctgcg
    14281 gtattcccct ggcattatga ctttcgcgtt taaccaacag ccaaaccagc aaacacgcca
    14341 ccacaggcac agcaaaatcc atcaggcttg ccacacccca tgcgtgcggc tcaaagctgc
    14401 cccgccatgg catattaatc cgcttgccat tttcgaacag ctgattggtt tagtccggtg
    14461 ttttcctgct tgcacttaaa aatgagcaga tgggaaactc tcgaaatggt tcgtcgatat
    14521 gctcaccttt cagtcaggca tttcaccgcg cacgcgagca aaatcaaagg cacaagagga
    14581 gaacgtagtt tacttaaatg tgagataact tattgattta aatggtgccg ataataggag
    14641 tcgaacctac gaccttcgca ttacgaatgc gctgctctac caactgagct atatcggccc
    14701 tgaaaggaca tgttcacgaa cgtgaatcac ggtggacaag gttaaaacta accgggcgat
    14761 gcgtcaatgg ccttgtgaat caaatggcta cttttgcatc acccggtttt atttacgcac
    14821 gaatggtgta atcaccgatg ccgatccact tgtaagtggt cagtgcttcc aggcccatcg
    14881 ggccacgcgc gtggagtttt tgtgtgctta ccgccacttc cgcgcccagt ccaaactggc
    14941 cgccgtcggt aaaacgcgta gaggcgttaa cgtaaacagc ggatgaatct acttcattaa
    15001 caaaacgctg ggcgttgcgc atatcgcggg tcaggatcgc atcggagtgt tgcgtgccgt
    15061 gttcacgaat atgggcgata gcatcgtcaa gatcgctgac aattttgacg ttcaagtcta
    15121 atgacaggaa ctcatcgtca tactcttcgg ctttaacagc caccaccttc gcggggcctg
    15181 cctgcaactg cgccagcgca gcagcatctg cgtgtaacgt cacgccactt tccgccattt
    15241 gcttgcttaa tgcgggcagg aagctatctg cgatgttttt atttaccagc aacgtttcta
    15301 ccgtattaca tgtgctcggt cgctgagttt tcgcgttgac gatcactttt aatgcttcag
    15361 cgatctctgc gctttcatca acgtaaatat ggcatacgcc tataccacca gtgatcaccg
    15421 gaattgtcga ctgttcgcgg cacagtttat gcaaaccagc cccgccgcgc gggatcagca
    15481 tgtcgatgta tttatccata cgcagcattt cactgaccag cgcacggtca ggattatcaa
    15541 tcgcctgcac ggcacccgcc ggtaagccac aggatttcag ggcgtcctga atcactgcca
    15601 ccgttgccgc gttagtgcga cacgtttctt tgccgccgcg caggatcact gcgttacctg
    15661 ttttcaggca cagcgaagcg acatcaaccg tcacgttcgg gcgcgcttca taaatcacgc
    15721 caataacccc cagcggtacg cgacgacgct ccagacgcag gccactgtcc agtacgccgc
    15781 catcgattac ccgccccacc ggatcggcga gattgcacac ctggcgcaca tcgtcggcaa
    15841 tgcctttcag ccgtgcgggc gtcagtgcca gacggtcaag catcgcttcg ctaaggccat
    15901 tggcacgcgc gtcagcaaca tcctgggcgt tagcgttgag gatgatttcg ctttgtgctt
    15961 ccagttcatc ggcgattttt tccagcacgc gatttttttc gcggctggag agttgcgcta
    16021 atttataaga ggcttgcttc gcggcaatgc ccatttgttc cagcatcagc ctgctcctta
    16081 acgggtaatc atgtcatcac ggtgaacggc aaccgggccg tattcatatc ccagtattgc
    16141 atcaatttct tgcgagtggt gtccggcaat acggcgtaat gcatcgctgt tgtaacgact
    16201 gacgccgtga gcgatatcgc gaccttcgag gttgcaaatg cggatgactt caccacgcga
    16261 gaagttgcca gtcacgcttt taatgccttt cggcaacagg gagctgccgc gttcgagaat
    16321 ggcggcggtt gccccttcat ctaccgtgat ttcacccgcc ggcggcgcac cgaaaatcca
    16381 gcgtttgcgg ttttcaagcg gagtcgcctg ggcatggaac aacgtaccga cggagatgcc
    16441 ttccatcaca tcaccaataa cgcccggctt gctgcccgcg gcaataatgg tgtcgatacc
    16501 cgcacggcaa gccacgtctg cggcctgcaa tttggtactc atgccgccag ttccgaggcc
    16561 tgaaacgctg tcaccggcaa tcgcgcgcag tgcgtcatca atgccgtaaa catctttaat
    16621 cagttctgcc tgcggattgc tgcgcgggtc agcggtatac aaaccttttt gatcggtcag
    16681 cagcaacagt ttatcggcac ccgccagaat cgccgccagc gcagaaaggt tatcgttatc
    16741 gccgacctta atctctgcag tcgcgacagc atcgttctca ttgattaccg gaacgatatt
    16801 gttatcgagc aacgcacgca tggtgtcgcg ggcgttcagg aagcgttcac ggtcttccat
    16861 atcagcacgg gtcagcaaca tctgcccgac atgaatgccg taaattgaaa acagctgttc
    16921 ccacagttga atcagtcgac tctgccctac cgccgccagc agttgtttcg aggcgatagt
    16981 cgctggcagt tccgggtaac ccaggtgctc acgtccggcg gcgatcgcgc ccgacgtcac
    17041 aataacaatc cgatgcccgg cggcatgtaa ctgcgcgcac tggcgaacaa gttcaacgat
    17101 atgggcacgg ttcaggcggc gcgatccgcc tgttagcaca ctggtgccga gttttaccac
    17161 cagcgtctgg ctgtcactca tgattctctg ccattcaatt ttaggaaaaa tgatatcaaa
    17221 cgaacgtttt agcaggactg tcgtcggttg ccaaccatct gcaagcaaag catggcgttt
    17281 tgttgcgcgg gatcagcaag cgtagcggca gttgtttacg cttttattac agatttaata
    17341 aattaccaca ttttaagaat atcattaatc tgtaatatat ctttaacaat ctcaggttaa
    17401 aaactttcct gttttcaacg gggctctccc gctgaatatt cgcgcgttaa ttaaaatcag
    17461 gaatgaaaat gaaaaagagc actctggcat tagtggtgat gggcattgtg gcatctgcgt
    17521 ccgtaaaggc cgcagaaata tataacaaag acggtaataa actggatgtc tatggcaaag
    17581 ttaaagccat gcattatatg agtgataacg acagtaaaga tggcgaccag agttatatcc
    17641 gttttggttt taaaggcgaa acacaaatta acgatcaact gacgggttat ggtcgttggg
    17701 aagcagagtt tgccggtaat aaagcggaga gtgatactgc acagcaaaaa acacgtctcg
    17761 cttttgccgg gttgaaatat aaagatttgg gttctttcga ttatggtcgt aacctgggcg
    17821 cgctgtatga cgtggaagcc tggaccgata tgttcccgga gtttggtggc gactcctccg
    17881 cacagaccga caactttatg accaaacgtg ccagcggtct ggcgacgtat cggaacaccg
    17941 acttcttcgg cgttatcgat ggtctgaact taaccctgca atatcaaggg aaaaacgaaa
    18001 accgcgacgt taaaaagcaa aacggcgatg gcttcggcac gtcattgaca tatgactttg
    18061 gtggcagcga tttcgccatc agtggagcct ataccaactc tgatcgcacc aacgagcaga
    18121 acctgcaaag ccgtggtaca ggcaagcgtg cagaagcatg ggcaacaggt ctgaaatacg
    18181 atgccaataa tatttatctg gcaactttct attctgaaac acgcaaaatg acgccaataa
    18241 ctggcggctt tgccaataag acacagaact ttgaagcggt cgcccaatac cagtttgact
    18301 ttggtctgcg tccgtcgctg ggttatgtct tatcgaaagg gaaagatatt gaaggaatcg
    18361 gtgatgaaga tctggtcaat tatatcgatg ttggtgctac gtattatttc aacaaaaata
    18421 tgtcggcatt tgttgattat aaaataaacc aactggatag cgataataag ctgaacatca
    18481 ataatgatga tattgtcgcg gttggcatga cctatcagtt ttaatggata ttgccggatg
    18541 tgatgcatcc ggcacatttc actcacgccg ttaacttcac cggttcatca cgaaaatcat
    18601 ccgccggttc cagcttcaga ttcagcgtcg ccagcagctc acgcagcttc tcatgaaact
    18661 cacgcagggt gtgctccagt cgttcaacca cttcagtgtc ttttaccgga acactcgtcc
    18721 agtcgcctgc tttatcgaac agaccaaact ggtaactgta ggtaaaacgg gattcctgcg
    18781 cttccagttc catccaccag ccccagaact cacgcacttc cggtgccggt ttcacgttga
    18841 cgcatacagc cagacaatcg aaaaagaatc gattatcttc gcacttacct tcacgaatat
    18901 acgggcctag tgcggtaaat tttttgatca atctgctctt cgggtgtcca ctcggtaacg
    18961 tcattgcaat ctcctgttgt gatgcaactg ttttaccaaa ttggtaaaat ttagcaaatt
    19021 tttaacacaa tcgtttttcg atccagtcgg tgatttcctg aagacctttg tcaaaattcc
    19081 gatacaccgg gttaaatggg atctctaaca atttaccgtc agcagatgat gaggtgatta
    19141 agcgtgagtc ctcttccggg ctgaacggat cgttcttcca gtagcctgat aacattggcg
    19201 ttgggcagcg acgtcccagc aatccttgca cttttaatga atagcgattc agctccacgc
    19261 gcaacgcttc gtcggaagca tcatgcatcc ccaaacggct cgccagaacg tcaagataca
    19321 tttccggcac ctgttgctgg cacttaaaat cactcaacag ggtatgaact accggaccaa
    19381 gacaggcaac cgctttcaga cgcggcgatt caaggtatgc cagacgcacg gcaacgttag
    19441 cgccgaaacg gaaaccaaag gccgcgacgc gagtgtgatc tacccacggt acgttaggca
    19501 gcgcctttaa gacgtgctga tgcaacaggc tggagtcctg ggtgagcttc cattttgaag
    19561 aaaagcccac cgacggcata tcaatagtca gcatcgcaat gccgcgcggc gcaaaataac
    19621 gttcatacag gctgtaatag tccgtctgca tcgcatccag accaccacac attaatactg
    19681 tcgggaacgg gccatcacct ttcggcatat gcaaaaagcc ggtgatgggc gcaccgccgg
    19741 gtacggtaaa ctccatctgc cgcatcgtgc ccggcagacg ctgagcggcc tcttcatagg
    19801 cgcggtttga caaagcctgc gcttgctcgg ccaggtcatc tcctttcaga tgaggatagg
    19861 cagcaatgtt gtacaacgta gccgcatgca gccagtgtcg accgctgagt tgcggatctt
    19921 cttccgcaca ggctttttgt tgccacacca tcgcctgggt agcccactca taaatccagt
    19981 tgccgccgcg gtagccaatc accgtatcgt ataaatcatc gtcggtacgt tcggcatcgc
    20041 tcatcacaat acgcgcctgg acgtcgagga tttcacgtgg gtcaatgccg cgccagatcc
    20101 acatcagacg gttaatcatg cgataccagt gagggatggt tttaccatca agggccgact
    20161 gcacaggcgg ttgtgcgccg tgattaaagc ggcggactag cgtcgaggtt tcaggatgtt
    20221 taaagcgggg tttgaacagg gtttcgctca ggtttgcctg tgtcatggat gcagcctcca
    20281 gaatacttac tggaaactat tgtaacccgc ctgaagttaa aaagaacaac gcccggcaat
    20341 gccaggcgtt gaaaagatta gcgaccggag attggcggga cgaatacgac gcccatatcc
    20401 cacggctgtt caatccaggt atcttgcggg atatcaacaa catagtcatc aaccagcgga
    20461 cgaccagccg gttttgcgaa gatggtgaca aagtgcgctt ttggatacat ttcacgaatc
    20521 gcaaccgcag taccaccggt atctaccagg tcatcaataa cgatgaagcc ttcgccatcg
    20581 ccttctgcgc gtttcagcac tttaagctcg cgctggttgt cgtgatcgta gctggaaata
    20641 caaacggtat cgacatgacg aatacccagt tcacgcgcca gtaacgcacc cggtaccaga
    20701 ccgccacggc ttacggcaat aatgcctttc cattgttcag aaggcatcag tcggcttgcg
    20761 agtttacgtg catggatctg caacatgtcc caggtgacga tgtatttttc gctcatgtga
    20821 agtgtcccag cctgtttatc tacggcttaa aaagtgttcg aggggaaaat aggttgcgcg
    20881 agattataga gatctggcgc actaaaaacc agtatttcac atgagtccgc gtctttttac
    20941 gcactgcctc tccctgacgc gggataaagt ggtattctca aacatatctc gcaagcctgt
    21001 cttgtgttga caacattttc tgctaaccct gtgacctgca atactgtttt gcgggtgatc
    21061 gacaaggaga cttaacgtgt ctgaactgtc tcaattatct ccacagccgc tgtgggatat
    21121 ttttgccaaa atctgttcta ttcctcaccc gtcctatcat gaagagcaac tcgctgaata
    21181 cattgttggt tgggcaaaag agaaaggttt ccatgtcgaa cgcgatcagg taggtaatat
    21241 cctgattcgt aaacctgcta ccgcaggtat ggaaaatcgt aaaccggtcg tcttgcaggc
    21301 ccacctcgat atggtgccgc aaaaaaataa cgacaccgtg catgacttca ctaaagatcc
    21361 tatccagcct tatattgatg gcgaatgggt taaagcacgc ggcaccacgc tgggtgcgga
    21421 taacggcatt ggtatggcct ctgcactggc ggttctggct gacgaaaacg tggttcacgg
    21481 cccgctggaa gtgctgctga ccatgaccga agaagccggt atggacggtg cttttggctt
    21541 acagagcaac tggttgcagg ctgatattct gattaacacc gactccgaag aagaaggtga
    21601 aatctacatg ggttgtgcgg gaggtatcga cttcacctcc aacctgcatt tagatcgtga
    21661 agcggttcca gctggttttg aaaccttcaa gttaacctta aaaggtctga aaggcggtca
    21721 ctccggcggt gaaatccacg ttggcctggg taatgccaac aaactgctgg tgcgcttcct
    21781 ggcgggtcat gcagaagaac tggacctgcg tcttattgat ttcaacggcg gcacactgcg
    21841 taacgccatc ccgcgtgaag cctttgcgac cattgctgtc gcagctgata aagtcgatac
    21901 actgaaatct ctggtgaata cctatcagga gatcctgaaa aacgagctgg cagagaaaga
    21961 gaaaaatctg gcattgctgc tggactctgt tgcgaacgat aaagctgccc tgattgcgaa
    22021 atctcgcgat acctttattc gtctgctgaa cgccaccccg aacggtgtga tccgcaattc
    22081 cgacgttgca aaaggtgtgg tcgaaacctc cctgaacgtc ggtgtggtga ccatgactga
    22141 caataacgta gaaattcact gcctgatccg ttcactgatc gacagcggta aagactacgt
    22201 ggtgagcatg ctggattcgc tgggtaaact ggctggcgcg aaaaccgaag cgaaaggcgc
    22261 atatcctggc tggcagccgg acgctaattc tccggtgatg catctggtac gtgaaaccta
    22321 tcagcgtctg ttcaacaaga cgccgaacat ccagattatc cacgcgggcc tggaatgtgg
    22381 tctgttcaaa aaaccgtatc cggaaatgga catggtttct atcgggccaa caatcaccgg
    22441 tccacactct ccggatgagc aagttcacat cgaaagcgta ggccattact ggacactgct
    22501 gactgaactg ctgaaagaaa ttccggcgaa gtaattacga taatgtccac gcctgcgggc
    22561 gtggacttct gtttgaagcc aatggctatc tatatcgaaa taacaaaaca ttatgaaact
    22621 catgaaaagg tcgcatattt atatagctgc gaccatattt catgggggga gtttctgatc
    22681 accaaagaaa gttttgcgct ggaatccgtg aaagaactta agggtgaaaa gcagaatttt
    22741 tatatgttca gagcctgggg caaagtcagg aaaacatact tagccacggg agaatttccc
    22801 caggaaacat gttacgccgc ttaaagtcag aattattttt tcatgcattt accattttgg
    22861 cattacgcct gtaccacatg gcaatggcgg caaccactaa tgccagttca agtaaaaacg
    22921 accagtgtaa taaaaaattg agccaccacg gatgatgtac cgccgtaata tgaaagagtg
    22981 caaagggttg gttaacgaaa ggcatcaacc accagatatc accgaccagc gtatcgagta
    23041 ataaatgcac gataccattc aggcaaaaca ccacgcccaa ccacgccgga agtttattct
    23101 tcgcaattgc ggcccaaact aatgtcgccg ccagcagagc aaaccataat aatggccaat
    23161 gagacgggta aagatgatga tggcgttgcc cgttatcaac cagatagcac cagaaaagat
    23221 caaaatcggg cgcaatggcc ccaactaagc caataaccat cgcccagcgc gcatgacgag
    23281 caatcagtgg caagcgtttc actaaagtac aagttattaa ataaccagcc ggaagatgac
    23341 cgataaacat gacgattcct ttcgttttgc ccgccgcttt catatagaaa acggcgggag
    23401 acattcctca attacacagc aacaaaagcc atcccggtaa atatccgtcg cggattgcca
    23461 cgttcaattt gatgatggaa cattcgccgc tgcgatttca gcgccgcgct attttcctgt
    23521 tgctgttgtt ccagcttcca ggcaatcagt aatcgcgcca gccgtttgtt agcatgctga
    23581 ctgcgctctg actgaacctt cacgctaata ccggatgcca gatgcgtggc gcgtaccgcc
    23641 gagtcggttt tattgacatg ttgaccgccc ggccccgacg aacgcagcgt ctcataacgg
    23701 atcgcgtcgg attgttcctg ctcatcagcg gtaaaacgcc caatgcccag aaaccagttt
    23761 ttgcgcccat gatgaggccg atacggactc ggacaaatcc actggatagt gccacaccag
    23821 ctttcgctta gagcccatgc gttatcgcca tccagagaaa tcagcgccga acgcagtgtg
    23881 tcagagtagc gacccgtttc tgtttccagc accgttaccg cgacgtcttg tcgggtagct
    23941 tctttaatca acctgtccag cgcctttttc actgccaggc aacattcttc cggcccctga
    24001 gctgaggaga gttgtagcaa gatcatcctt ttttccctcc attgtttttg agcgttagca
    24061 ccggacgcag ccgcgcgaca ggaataatta aaccggcctg caccagacat tgcaccacgc
    24121 tttcagccga tttataggct tgtggcgctt cttcaaagat gagttgttta tcgcgacaaa
    24181 ttacccgact gccaagttca gtacgcgaga gttgcgtcgc cgtgtatttc gctgccagac
    24241 gccctttaca ctcggtgcgc ccccatttac gccctgcccc atgcgccagc gagtggagtg
    24301 ttttttcgtt cgcaacaggt ttaaccagcc aggagtaatc accgcgtgaa ccgggaataa
    24361 tcaccagacc gttgtcatcc ggcgtggcac ctttacgatg caaccagccc tgttgatcgc
    24421 cgatttgaca ggcgctaaca aagttatgcg ccacatccag aacaggactt ccggtggcct
    24481 taacctgttg cattatgcgc aaagcgatca tctggcgatt aatacgcgca aacgccagcg
    24541 catcgtcatg ttccgcaata taccgtagcg cgtcgtcact gccttcaggc aaaccatgat
    24601 gcgaaaacga ggcaatatgc cgctgtaaaa tagactgccc cagccccctc gagccgctat
    24661 gaaccagcag ttgcagatgc tgcgcatcca gacctgtcag tgcaaacagt tcagcgtcga
    24721 taatttgatc aacttgttgc agttctgcga agtggtttcc gccaccgatg gaacccagcg
    24781 agctgcgcca cggatgctgt gctaacgctg acggcaggtt ttcctccagc cagctttctt
    24841 cagcaacgtc atccagcgca gataatcgct tttcaaactt atcggcgttg tatttgcgcg
    24901 cgaaaatatc tgtttgccat agcgccatac cgcagccgat atcattgccg accagtgccg
    24961 ggtaaaaacg gcctacggag aagaacgctg cgccaatcgg atagccgcgt ccgggatgta
    25021 aatctggcat ccctactacg cgttgcatgt tgggtaaatt tgccgtggtg tgtaattgtt
    25081 ggatcgctaa actctcgatc cacaggtcat cagatgcgat ggtaaatacc gcatcggata
    25141 agggacgaat atatttgccc atgtaccatt ccatttatga ataaaaatca ggaaatggca
    25201 gacgaatcca gggcaagaaa aaaagaatta atcctggaaa ggtctgcaaa gagtcattga
    25261 taaaggattt gtcatgattt acctccttgc agtttgtgga ataagaaaac gcacacatac
    25321 taggcgggcg ttattttcat tgcaagctgg atttaatgtt gcggtttata tcgcatataa
    25381 aaattagtaa accactctcc ccggcattca acgcactgct gcttaactgt ctgaaaacca
    25441 taacgttcaa aaaagggctt tgcggttatg ctggcgtcca ccgtaagttc ggattcagac
    25501 ttaatcaatg gttttaacaa agcgctggca accccgcgtc gggtgtattc aggttcaaca
    25561 aataacatat cgatataatg ttcaatgcgg gtaataaaac caaccggttg tgcattaata
    25621 actgcaaccc gcacttgtga tttcgcgagt ttctccttcc agcgagattc gtcaatctgc
    25681 gcccaggcgg caatttgttg tggtgaataa tgctgactgg cggtcatcgt aaccgctcta
    25741 aggaaaatag cgcatagttg ctgaaaatcg ccaggctgat agtttcttat ttgtatgtta
    25801 ttcataatat aaattcaaaa acgcatgcga aacgcttctg ccattttccc aattttatgc
    25861 atttggttgt tatctcgagc cagtttatga ggttcaggtt tcagaatggc aatgagcaac
    25921 catgcttgct catcaaacgc accctgacaa tataccaaat gcgcttcgtc attcgttctg
    25981 ctgaattggc gcaactgtgg cggaaatgga ttattcacat ttgccagatg aatatgagca
    26041 actcgctcaa atttgattaa tggccaggta aacgagtcgt cgtagagtgc atcgcgacca
    26101 aatatatctg gcaaaacacc gtcacgctta taggaaataa aatccgctgt taacgcatca
    26161 agttcctctg ctgtaagttg caggcgaata agttttgttt tgaatacccg catccttatt
    26221 ccttaaagtc attgaaatca tcatccgtca tatcattaag atattgttca gcgcggcgtg
    26281 taatttcctc taatcttgcg gcactcggac ggaagcgcgc cttaaccagt tttttctcct
    26341 cttgttcagc aagcatgtcc attaacgctt caaatgcgct ggcacttaag agatatcctg
    26401 cggggcgatt attagaaaga accgcaaccg gttgatcaat aaagtattta gctgggtttt
    26461 tacgtaactc agtgatattg accgattttt cagcgagaat tcgatgcata cagtgatccc
    26521 ctcataataa tgaacatcag aatatacata atagtataca tcataatccc agcaccagtt
    26581 gtctttccat ttgagggtca agcaacgtca catgcagccc caccagtcgc acaccgcgcc
    26641 cgccgcgacg ttcatcccag gttttacgcg cggtggcgat cagatcagct ttattcagcc
    26701 gcggccagac gtgctcctga gtagtttgct gaaaatcgtc gaactttaat ttcaccccct
    26761 ggcgagcaat cagtaaatca ggttttacct ttgccagacg gcgttcaagt tcaggataca
    26821 gcagctcgat aatcgcttca cattcagacc agtgatgaat atcttccgcc atcgtgcgtt
    26881 ccacgccgac ggattttcgc aaccgctcgc tgttaacgtc gcgctcgtca atcccctgac
    26941 tacgctccca caaaatgcgg ccaaatttgc caaaacgttt gagcagagtc accagatcac
    27001 acttttgcac atcaccgcag gtccgcagcc ccatcgcttc cagttttgcc gccgagactt
    27061 tgccgacgcc gggaattttt gccagcggta aggtttgcag aaatgccgga acttctgccg
    27121 gcgtaatcac aaactgaccg ttgggtttat tcatgtcgga agcaattttg gcgagaaact
    27181 ttaccggcgc aacgcccgca gatgccgtca gttgcagctc gttaaagatc gtctgacgga
    27241 tttcctgggc gatgagggtc gcagaaccgt ggcaatgcac actatcggtg acgtcgagat
    27301 aggcttcatc cagtgataac ggttcaatgc gcgaggtata gcgcgagaaa atttcgcgga
    27361 tatgatttga ggcttctttg taggcgtcaa agcgccctgg aagcagcgtg agatgtgggc
    27421 ataatttgag cgccatccct gtcggcatag cgctgcgtac gccaaattta cgcgcgggat
    27481 aattggcggt gctgatcacc ccccgacgtt cgcggctgcc gccaatagca atagggatat
    27541 cgcgcagggc gggattgtcg cgcatctcca ccgctgcgaa aaagcagtcc atatccacat
    27601 gaatgatttt acgcattgct cacctctcaa cactggtaaa gtatacagtg atttcagagt
    27661 ttgagaaatg cgtaaagatt cagcatttaa cgcgttcgct gtgaaagcac ctgctgctta
    27721 tccagctttt gcaccagcgg ctgcaccact ttatccccat gctgaccaaa gtattgatac
    27781 agcgtatcgg acgcgctttt agtcagcacc ataatctcaa tgcgccggtt gcccgcgctt
    27841 tgcggatttt tcgcgtccag cagcatctgg tccgccattg cgctcacctg catcacttta
    27901 tcttccggca ttcctgcctc ttccagcgcc cgacgagccg aaagcgcgcg gtcacccgaa
    27961 aggttccagt tattgtagat attgtttttg taggccatcg catcggtatg cccggtaata
    28021 ataattttgt tatcgagcga gtcgaacact ggcgcaagct ccaccagcaa agttttaaag
    28081 aacggcataa tctgtgcgct gccgcgttcg aacatattgc ggttctggtc gtctttaatc
    28141 agcacgcgta atccctgggg aacaatctcc atctccagat tcgcttccat atgcgcatca
    28201 cgggcgatgg tattgatact ggtcgccagc tcgccaagct cggtggcgga tttcttcttc
    28261 agcagcgccg ttttctcgtt gacgtcgcgc gcttttttct ccgtctcttc cggcactgcc
    28321 acggtggcag gttttgacgg atgagacggg ctgattttat ttaacggcga cagcccgcca
    28381 ccgttaaaaa tcgactgccc gtgtagcgcg gcgataatgc tttcacgctc ggatttactg
    28441 acgctgttga caatcaactt tatcgtcgtc accaaagggg ccgagcgtat ttccgaggtt
    28501 tctgcccgct ttaccctgga cgcgatgccc ggtaaacaga tggcgattga cgccgatctt
    28561 aacgccggat tgatcaacca ggcgcaggca caaacccggc gtaaagatgt tgccagcgag
    28621 gccgatttct acggcgcaat ggacggggca tcgaagtttg tgcgcggcga tgccatcgcc
    28681 gggatgatga ttctggcgat caacctgatc ggcggcgtct gtatcgggat cttcaaatac
    28741 aacctgagcg ccgacgccgc cttccagcaa tatgtgctga tgactatcgg cgacgggctg
    28801 gtggcgcaga tcccgtccct gctgctctcc accgcggcgg caattatcgt cacccgcgtc
    28861 agcgacaacg gcgatatcgc ccatgacgtg cgccaccagc tgctggcaag tccgtcggtg
    28921 ctctacaccg ccaccgggat catgtttgtg ctggcggtgg tgccggggat gccgcatctg
    28981 ccatttttgc tgttcagcgc cctgcttggc tttaccggct ggcggatgag caaacgcccg
    29041 caggcggcgg aggcggagga gaaaagcctc gaaacgctga cccgaaccat caccgaaacc
    29101 agcgagcaac aggtcagttg ggaaaccatt ccgctgatcg agcccatcag cttaagcctc
    29161 ggctacaagc tggtggcgct ggtggacaaa gcgcagggga acccgctcac ccagcggatt
    29221 cgcggcgtgc ggcaggtgat atccgacggt aacggcgtgc tgctgccgga gatccgtatt
    29281 cgggaaaact tccgtctcaa gcccagccag tacgccattt tcatcaacgg cattaaggct
    29341 gatgaagcgg atattccggc ggataaactg atggccctgc cctccagcga aacctacggc
    29401 gagattgacg gcgtactggg gaatgacccg gcatatggga tgccggtcac ctggattcag
    29461 cctgcgcaga aagcgaaggc gctgaatatg gggtatcagg tgatcgacag cgccagcgta
    29521 attgccacgc atgtgaataa gattgtgcgc agctatattc ctgatttatt taactatgac
    29581 gatattacgc agttgcataa ccgcctgtcg tcgatggcac cgcgactggc ggaggatttg
    29641 agcgcggcgc tgaattacag ccagttgctg aaagtgtacc gggcgctgct gactgaaggc
    29701 gtttccctgc gcgatatcgt caccatcgcc accgtgctgg tcgccagtag tgcggtgacc
    29761 aaagatcata ttctgctggc ggcagatgtg cgcctggcgc tgcggcgcag cattacccat
    29821 ccgttcgttc gcaagcagga gctgacggtg tatacgctga ataatgagct ggaaaatctg
    29881 ctgaccaacg tggtgaatca ggcgcaacag gccggcaaag tgatgctcga cagcgtgccg
    29941 gtagacccga atatgctcaa ccagttccag agtacgatgc cgcaggtgaa ggagcagatg
    30001 aaagcggcgg ggaaagaccc tgtgctgctg gtgccaccgc agttgcgccc tttgctggcg
    30061 cgctatgcga gattgtttgc gccggggctg catgtgctgt cgtataacga agtgccggac
    30121 gagctggagt tgaagattat gggggcgttg agttgatggg ggagactata taaggtctcg
    30181 gactgtcccc tcgccccttt ggggcgaggg agaaaaacgt gtacgacttt aactttttcg
    30241 cagtattgcc gtcctacaaa atcgtctctt ccgtcaaaat ccgccgcgcg cctaaaaaat
    30301 gatcctgcca gaaaggttca gctaaccggc ttatccgaat ggtttcgccg gtacgtggtg
    30361 actcgataaa ctgaccgtct cccagataca cccccatatg atcggctatc tcgcggctgt
    30421 gaatatggaa aaacagcaaa tctccccggc gcaggtcgtt gttcgccaca atcgttgccc
    30481 gatggtagtg atacatctca ttggctgtgc gcgggagctt cgcctcaagg atcttgttgt
    30541 aggcataaaa aaccaacccg ctacagtcga agcctttatc gggccgcgtg ccgccccaga
    30601 cataaggctt gccaagctgc tgctccaggc ggtgaatcgc cacttcggtg atgttatgca
    30661 ggtgatcgct gcttaaaaag tggttgtttt ccgccagcgc ctgccagcgt ctgtcactcg
    30721 ccttgagcgg cgcaggaaac cattctggat gctgttttat ctgctcccgg ttgtgctggc
    30781 gtagcgccct tctgctttcg gcattgcctt ccacaatata gctggcctgt tttttcagat
    30841 gggtttggta ctgttttaat aaacgcgcac ggttttgcat ccgctggcgg gcggcgtagc
    30901 tgaaagagat atgtgatgtg gtggcgctgg caaatgaaga aaacggcaag caaagcaaca
    30961 gtaatcccga caacacaaaa gagggaatcg acggcaaaga cattctcaat aatggctggt
    31021 catgcattga tgttgcagtg tatcccggcc cgtacctgaa caaacttaat aaaccattat
    31081 tataaaatta ataaatatat ttcagttaat tatgtaaaaa catccgttta ttaaattact
    31141 catggattgt cgctgttgct catttgagct acaattcaag ctgaataaat atacagcaca
    31201 ggagatatcc caatggctgc taacgcgttt gttcgcgccc gaatcgatga agatctgaag
    31261 aatcaggcgg cggacgtact ggccgggatg gggctgacca tctctgacct ggttcgcata
    31321 accctcacaa aggtcgcgcg tgaaaaggca ttgccgtttg atttacgcga gcctaatcaa
    31381 ttaactattc aatcaatcaa aaacagcgaa gctggcgttg gtattcataa ggccaaagac
    31441 gccgatgatt tatttgataa attaggaatt taaatatgat tcaaagggat attgaatact
    31501 cgggacaatt ttcaaaggat gtaaaacttg cacaaaagcg tcataaggat atgaataaat
    31561 tgaaatatct tatgacgctc ttatcaataa tactttactg cttccagctg tttataaaga
    31621 ccacccgctg caaggttcat ggaaaggtta tcgcgatgct catgtcgaac cggactggat
    31681 cctgatttac aaacttaccg ataaactttt acgatttgag agaactggaa ctcacgcggc
    31741 gctatttggg taaagcccgc tgccgatgaa atttgtaaac cctgcgccga caggcttgcg
    31801 taaaactctt ttggtgataa tgtgagcctt ccaaatccag actattccga tttgggatcc
    31861 attttgccgt cctggcgtgt gtaaccgttt tatcaaggaa taagcagtat gcgtaaaatc
    31921 gcattaattc ttgcgatgtt gttgatcccg tgcgtttcgt ttgccggttt gctgggcagc
    31981 agtagctcga ccacgccagt gagcaaagag tataagcagc agttgatggg atcccctgtc
    32041 tacatccaga tcttcaagga agaacgtacg ctcgatctct acgtcaaaat gggcgagcaa
    32101 tatcaactgc tcgacagcta taaaatctgt aaatattccg gcggcttagg gccaaaacag
    32161 cgtcagggcg atttcaaaag cccggaaggg ttttatagcg tccagcgtaa tcagttaaaa
    32221 ccagacagcc gttactacaa agcgattaat attggattcc ccaatgccta tgaccgtgcg
    32281 catggttatg aagggaaata tctgatgatc cacggcgatt gtgtttccat cggctgctac
    32341 gcgatgacca atcagggtat tgatgagatc ttccagttcg ttactggtgc gctggtgttt
    32401 ggtcagccga gcgtgcaagt gagtatttac ccgttccgca tgaccgacgc caatatgaag
    32461 cgccataaat attccaactt taaggacttc tgggagcaac tgaagccggg ctacgactac
    32521 tttgagcaaa cccgtaagcc accgaccgtt tctgtggtca atggccgtta cgtggtcagc
    32581 aagccgttaa gccacgaagt tgtgcagcca cagctggcat caaactacac gctccccgag
    32641 gcaaaataag cgccattcgc ctggcataat cttttgccag gtttcattgc ccgtcagcgg
    32701 ctgtgttgca atcaccgtga ccacatcatt cggtgtggtc tgcgagctga agtcgatttc
    32761 cacatcctga tccagcaacg ttgccacgcc aaacggcgcg cggcgggtga tccagtgtaa
    32821 attagtcgag caatacgcca ttacatagcg tccgtcagaa agcagcatgt tgaaaacgcc
    32881 cttctgccgc agttcatccg ccagtgaggc gatatattta aacactgccg ccatattgcc
    32941 cggtgtgcgc gggtaacgct gcgttaattt atgcaggagc cagcagaagg ctttttcgct
    33001 gtcggtttca ccgaccgggc ggaagttgcc ggtttccagt gatttgtacc ccgtcagttg
    33061 cccgttatgg gcataagtcc agttacgtcc ccataactcg cgggtaaacg ggtgagtatt
    33121 ttccagcgcc acctcgcccc gattggcctg gcgaatatga gccacaaccg aacaggattt
    33181 tatcgggtag tcctggacaa gtttggcgat gggggaatta aagctgggtt gtggatcttt
    33241 aaatgtgcga cagcctttac cttcgtaaaa ggtgatgccc cagccatctt tatgtggccc
    33301 ggttccacca ccacgctgta caagcccggt gaaactaaag cagatatcag tagggacgtt
    33361 ggcgctcatc ccgagcaatt cgcacatggg taacctccac aacagcggga gcgcatggcc
    33421 cccggcgaag attgattaaa aagtacaaag gtgcaggctg ttaccctcac cccggccctc
    33481 tccctgaaag ggagaaaaga ccttacttaa ccatctcttt ttcaattaac tggatcagga
    33541 tatggatcac tttaatgtgg atctcctgaa tgcggtcggc ataaccaaag tgcggaacgc
    33601 gaatttcaat atccgccgtg ccagccattt tgccgccatc tttaccggtc agggtgatca
    33661 ctttcatccc cttctcacgc gccgctgcga tcgctttgat cacgtttgca gagttaccgg
    33721 aggtagagat ccccagcagt acatcgcctt cgcgacctac cgcttcaacg taacgggaga
    33781 aaatatcatt gaaaccaaaa tcgttaccga cgcaggaaat atgactaacg tcagaaatgg
    33841 caatcgccgg gtagcccgga cggttttcac ggtagcgccc cgtcaactct tcagcaaagt
    33901 gcatagcgtc gcaatgggag ccgccgttgc cgcaagaaag cactttgcca ccgcctttaa
    33961 agctgtctgc taacaggacc gccgcgcgct gaatggcgtg aatattggcg tcatctttta
    34021 aaaaattagc cagcgtttcc gccgcttcgt tcagttcgtt acgaataaga tcctggtaca
    34081 tgaggatatc cttcagcata aatgtaatag acaaaatgca gtgtaccgga taccgccaaa
    34141 agcgagaagt acgggcagat gctatgacca ggactttttg acctgaagtg cggataaaaa
    34201 cagcaacaat gtgagcttcg ttgtaattat attgtaaaca cattgctaaa tgtttttaca
    34261 tccactacaa ccatatcatc acaagtggtc agacctccta caagtaaggg gcttttcgtt
    34321 atgatgattt tgagtattct cgctacggtt gtcctgctcg gcgcgttgtt ctatcaccgc
    34381 gtgagcttat ttatcagcag tctgattttg ctcgcctgga cagccgcact cggcgttgct
    34441 ggtctgtggt cggcgtgggt actggtgcct ctggccatta tcctcgtgcc atttaacttt
    34501 gcgcctatgc gtaagtcgat gatttccgcg ccggtatttc gcggtttccg taaggtaatg
    34561 ccgccgatgt cgcgcactga gaaagaagcg attgatgcgg gcaccacctg gtgggagggc
    34621 gacttgttcc agggcaagcc ggactggaaa aagctgcata actatccgca gccgcgcctg
    34681 accgctgaag agcaagcgtt tctcgacggt ccggtagaag aagcctgccg gatggcgaat
    34741 gatttccaga ttacccatga gctggcggat ttgccgccgg agctgtgggc gtatcttaaa
    34801 gagcatcgct tcttcgcgat gatcatcaaa aaagagtacg gcgggctgga gttctcggct
    34861 tatgcccagt ctcgcgtgct gcaaaaactc tccggcgtga gcgggatcct ggcgattacc
    34921 gtcggcgtgc caaactcatt aggcccgggt gagctactgc aacattacgg cactgacgag
    34981 cagaaagatc actatctgcc gcgtctggcg cgtggtcagg agatcccttg ctttgcactg
    35041 accagccccg aagcgggttc cgatgcgggc gcgattccgg ataccgggat tgtttgcatg
    35101 ggcgagtggc agggccagca ggtgctgggg atgcgactga cctggaacaa acgctacatt
    35161 acgctcgcgc cgattgcgac cgtgcttggt ctggcgttta aactctccga cccggaaaaa
    35221 ctgctgggtg gcgcagaaga tttaggtatt acctgtgcgc tgatcccgac caccacgccg
    35281 ggcgtggaaa ttggtcgtcg ccacttcccg ctgaacgtgc cgttccagaa cggaccgacg
    35341 cgcggtaaag atgtcttcgt accgatcgat tacattatcg gcggaccaaa aatggccggg
    35401 caaggctggc ggatgctggt ggagtgcctc tcggtaggcc gcggtatcac cctgccttcc
    35461 aactcaaccg gcggcgtgaa atcggtagcg ctggcaacgg gtgcgtatgc gcacatccgc
    35521 cgtcagttca aaatctctat tggtaagatg gaagggattg aagagccgct ggcgcgtatt
    35581 gccggaaacg cttatgtaat ggatgctgcg gcatcgctga ttacctacgg cattatgctc
    35641 ggtgaaaaac ctgccgtgct gtcggctatc gttaagtatc actgtaccca ccgtgggcag
    35701 cagtcgatta ttgatgcgat ggatatcact ggtggcaaag gcattatgct cgggcagagc
    35761 aacttcctgg cccgtgctta ccagggcgca ccgattgcca tcaccgttga aggggctaac
    35821 attctgaccc gcagcatgat gatcttcgga caaggagcga ttcgttgcca tccgtacgtg
    35881 ctggaagaga tggaagcggc gaagaacaat gacgtaaatg cgttcgataa actgctgttc
    35941 aaacatatcg gtcacgtcgg tagcaacaaa gttcgcagct tctggctggg cctgacgcgc
    36001 ggtttaacca gcagcacgcc aaccggcgat gccactaaac gctactatca gcacctgaac
    36061 cgcctgagcg ccaacctcgc cctgctttct gatgtctcga tggcggtgct gggcggcagc
    36121 ctgaaacgtc gcgagcgcat ctcggcacgt ctgggggata ttttaagcca gctttacctc
    36181 gcctctgccg ttctgaagcg ttatgacgac gaaggccgta atgaagccga cctgccgctg
    36241 gtgcactggg gcgtacagga tgcgctgtat caggcagagc aggcgatgga cgatttactg
    36301 caaaacttcc cgaaccgcgt ggttgccggg ctgctgaatg tggtgatctt cccgaccgga
    36361 cgtcattatc tggcaccttc tgataagctg gatcataagg tggcgaagat tttacaagtg
    36421 ccgaacgcca cccgttcacg tattggtcgc ggtcagtacc tgacgccgag cgagcataac
    36481 ccggttggtt tactggaaga ggcgctggtg gatgtgattg ccgccgaccc aattcatcag
    36541 cggatctgta aagagctggg taaaaacctg ccgtttaccc gtctggatga actggcgcat
    36601 aacgcgctgg cgaaggggct gattgataaa gatgaagccg ctattcttgt gaaagctgaa
    36661 gaaagccgtc tgcgcagtat taacgttgat gactttgatc cggaagagct ggcgacgaag
    36721 ccggtaaagt tgccggagaa agtgcggaaa gttgaagccg cgtaattgaa taacggagcc
    36781 gaaaggctcc gtttctttat ccgctaatta tttaaaatta aagccatccg gatggttttc
    36841 caggctgccg gtcaacgccg cgaacagcac cgttttacca tcaatagaaa gcgcatcgtt
    36901 cacattcaac caggtgagtt tctcttgcga cgttttctca tcaatggtcg agaacagccc
    36961 cgtcatctga ttagatttct cggaccacat cacagcgata cgttgcgagc cacagtcatg
    37021 cggtttgcac gcgctcatca cctgatacgt ctcatctccc aacgttacgg tttgtgcagg
    37081 ggtataagta ccgcctttca tcacccaggc aggcagctta tgcccttgca ccatctgatt
    37141 aaacgccgct ttggtggttt cgccctttgc aaggctgcta atggttaaat catcctgcgc
    37201 cattgcactg gtggcgatga ccagagcggc gactgtcgtt attgccttaa acatcattcc
    37261 tcccgagctt atcctgccca tgttattaac ctcctaaagc ctggcgataa cacgataatt
    37321 tgcaaatcag atatttccaa tatcagcatt tgttatcaat ttattctgcg ctaaggcaac
    37381 tgcctgataa ggtgttagag ttataaaacc cttcgcataa aggagttgta caccgtgcct
    37441 ggtttgaaga ttacgctttt gcagcaacca ctggtgtgga tggatggccc tgccaacctg
    37501 cgccattttg atcgtcaact ggaaggtatt accgggcgcg atgtgatcgt tctaccggag
    37561 atgtttacca gcggctttgc catggaagcg gcagcttcgt cgctagcaca aaatgacgta
    37621 gtgaactgga tgacagctaa ggcgcagcag tgcaatgcgc tgattgcagg cagtgttgca
    37681 ttacaaacgg agtctggttc ggttaaccgc tttttgctgg ttgagccggg cggcacggta
    37741 catttttatg ataagcgtca tctgttccgc atggcagatg agcatctgca ttataaagcg
    37801 ggcaatgcgc gagtgattgt ggaatggcgc ggctggcgta ttttgccgct ggtgtgctac
    37861 gacttacgtt ttcctgtgtg gtcgcgcaat ctcaacgatt atgacctcgc cctgtacgtc
    37921 gccaactggc ctgctccgcg ctctctgcac tggcaggcat tgctgacagc ccgcgcgatt
    37981 gagaatcagg cgtatgtggc gggatgcaat cgcgtcggca gcgatggcaa cggctgccat
    38041 tatcgtggtg acagcagggt gattaatcca cagggcgaga ttatcgctac tgccgacgcg
    38101 catcaggcaa cgcgcattga tgcggagctg tcgatggtgg cattgcggga atatagagaa
    38161 aagtttccgg catggcggga tgcggatgag tttaggttgt ggtgagtggt gttgtattta
    38221 aggccgggga gagtcgggga agactacgaa agcccgctct cctgcgacca cttttatcat
    38281 aggagtgtgg aagtgctttt ccatcaatcg cgatgacgtc tttgtcattt gatgaatggc
    38341 aatcacgcat ccagttaatt gtattagtcg cgacttgatc tgacactgag ccttgaaagg
    38401 ttgagagtta ccggttttga tatgggtgtc gaatcagggc aagattagac cctgtaaata
    38461 attctgtgta actgcccacg attaaaggtg gtcgctcagg cggtcaccgt attcgataat
    38521 aaatcgactc atagccaacc gccagttgat gatcggcatt gtccattttg tcgccgccgc
    38581 ctcagttgca agccagatga ctttgcgtac tgattcgtcc gtcgggaaca
//
LOCUS       DADXDL010000039        38230 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.039, whole genome shotgun sequence.
ACCESSION   DADXDL010000039 DADXDL010000000
VERSION     DADXDL010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38230)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38230)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38230
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.039"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(104..391)
                     /locus_tag="IRB70_002325"
     CDS             complement(104..391)
                     /locus_tag="IRB70_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebO family protein"
                     /protein_id="HBC0632230.1"
                     /translation="MNEVVNSGVMNIASLVVSVVVLFIGLILWFFINRASSRTNEQIE
                     LLEALLDQQKRQNALLRRLCEANEPEKADKKTVESQKSVEDEDIIRLVAER"
     gene            complement(466..609)
                     /gene="mgrB"
                     /locus_tag="IRB70_002326"
     CDS             complement(466..609)
                     /gene="mgrB"
                     /locus_tag="IRB70_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP/PhoQ regulator MgrB"
                     /protein_id="HBC0632231.1"
                     /translation="MKKFRWVVLVVVVLACLLLWAQVFNMMCDQDVQFFSGICAINQF
                     IPW"
     gene            768..1007
                     /locus_tag="IRB70_002327"
     CDS             768..1007
                     /locus_tag="IRB70_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632232.1"
                     /translation="MRFIIRTVMLIALVWIGLLLSGYGVLIGSKENAAGLGLQCTYLT
                     ARGTSTVQYLHTKSGFLGITDCPLLRKSNIVVDNG"
     gene            complement(1151..1942)
                     /gene="kdgR"
                     /locus_tag="IRB70_002328"
     CDS             complement(1151..1942)
                     /gene="kdgR"
                     /locus_tag="IRB70_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator KdgR"
                     /protein_id="HBC0632233.1"
                     /translation="MANADLDKQPDSVSSVLKVFGILQALGEEREIGITELSQRVMMS
                     KSTVYRFLQTMKTLGYVAQEGESEKYSLTLKLFELGARALQNVDLIRSADIQMREISR
                     LTKETIHLGALDEDSIVYIHKIDSMYNLRMYSRIGRRNPLYSTAIGKVLLAWRDRDEV
                     KQILEGVEYKRSTERTITSTEALLPVLDQVREQGYGEDNEEQEEGLRCIAVPVFDRFG
                     VVIAGLSISFPTLRFSEERLQEYVAMLHTAARKISAQMGYHDYPF"
     gene            2119..3492
                     /locus_tag="IRB70_002329"
     CDS             2119..3492
                     /locus_tag="IRB70_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416342.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0632234.1"
                     /translation="MPKVQADGLPLPQRYGAILTIVIGISMAVLDGAIANVALPTIAT
                     DLHATPASSIWVVNAYQIAIVISLLSFSFLGDMFGYRRIYKCGLVVFLLSSLFCALSD
                     SLQMLTLARVIQGFGGAALMSVNTALIRLIYPQRFLGRGMGINSFIVAVSSAAGPTIA
                     AAILSIASWKWLFLINVPLGIIALLLAMRFLPPNGSRASKPRFDLPSAVMNALTFGLL
                     ITALSGFAQGQSLTLIGAELVVMVVVGIFFIRRQLSLPVPLLPVDLLRIPLFSLSICT
                     SVCSFCAQMLAMVSLPFYLQTVLGRSEVETGLLLTPWPLATMVMAPLAGYLIERVHAG
                     LLGALGLFIMAAGLFSLVLLPASPADINIIWPMILCGAGFGLFQSPNNHTIITSAPRE
                     RSGGASGMLGTARLLGQSSGAALVALMLNQFGDNGTHVSLMAAAILAVIAACVSGLRI
                     TQPRSMA"
     gene            complement(3538..4419)
                     /gene="htpX"
                     /locus_tag="IRB70_002330"
     CDS             complement(3538..4419)
                     /gene="htpX"
                     /locus_tag="IRB70_002330"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014229823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease HtpX"
                     /protein_id="HBC0632235.1"
                     /translation="MMRIALFLLTNLAVMVVFGLVLSLTGIQSSSVQGLMIMALLFGF
                     GGSFVSLLMSKWMALRSVGGEVIEQPRNERERWLVNTVATQARQAGIAMPQVAIYHAP
                     DINAFATGARRDASLVAVSTGLLQNMSPDEAEAVIAHEISHIANGDMVTMTLIQGVVN
                     TFVIFISRILAQLAAGFMGGNRDEGEESNGNPLIYFAVATVLELVFGILASIITMWFS
                     RHREFHADAGSAKLVGREKMIAALQRLKTSYEPQEATSMMAFCINGKSKSLSELFMTH
                     PPLDKRIEALRTGEYLK"
     gene            complement(4611..6659)
                     /gene="prc"
                     /locus_tag="IRB70_002331"
     CDS             complement(4611..6659)
                     /gene="prc"
                     /locus_tag="IRB70_002331"
                     /EC_number="3.4.21.102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy terminal-processing peptidase"
                     /protein_id="HBC0632236.1"
                     /translation="MNMFFRLTALASLLAIAGQTFAVEDITRADQIPVLKEETQHATV
                     SERVTSRFTRSHYRQFDLDQAFSAKIFDRYLNLLDYSHNVLLASDVEQFAKKKTELGD
                     ELRSGKLDVFYDLYNLAQKRRFERYQYALSVLEKPMDFTGNDTYNLDRSKAPWPKNEA
                     ELNALWDSKVKFDELSLKLAGKTDKEIRETLTRRYKFAIRRLAQTNSEDVFSLAMTAF
                     AREIDPHTNYLSPRNTEQFNTEMSLSLEGIGAVLQMDDDYTVINSMVAGGPAAKSKAI
                     SVGDKIVGVGQTGKPMVDVIGWRLDDVVALIKGPKGSKVRLEILPAGKGTKTRTVTLT
                     RERIRLEDRAVKMSVKTVGKEKVGVLDIPGFYVGLTDDVKVQLQKLEKQNVSSVIIDL
                     RSNGGGALTEAVSLSGLFIPSGPIVQVRDNNGKVREDSDTDGQVFYKGPLVVLVDRFS
                     ASASEIFAAAMQDYGRALVVGEPTFGKGTVQQYRSLNRIYDQMLRPEWPALGSVQYTI
                     QKFYRVNGGSTQRKGVTPDIIMPTGNEETETGEKFEDNALPWDSIDAATYVKSGDLTA
                     FEPELLKEHNARIAKDPEFQNIMKDIARFNAMKDKRNIVSLNYAVREKENNEDDATRL
                     ARLNERFKREGKPELKKLDDLPKDYQEPDPYLDETVNIALNLAKLEKARPAEQPAPVK
                     "
     gene            complement(6679..7377)
                     /gene="proQ"
                     /locus_tag="IRB70_002332"
     CDS             complement(6679..7377)
                     /gene="proQ"
                     /locus_tag="IRB70_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707288.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone ProQ"
                     /protein_id="HBC0632237.1"
                     /translation="MENQPKLNSSKEVIAFLAERFPHCFSAEGEARPLKIGIFQDLVD
                     RVAGEMNLSKTQLRSALRLYTSSWRYLYGVKPGATRVDLDGNPCGELDEQHVEHARKQ
                     LEEAKARVQAQRAEQQAKKREAAAAAGEKEDAPRRERKPRPTSPRRKEGAERKPRSQK
                     PVEKAPKTVKAPREEQHTPVSDISALTVGQALKVKAGQNAMDATVLEITKDGVRVQLN
                     SGMSLIVRAEHLVF"
     gene            complement(7474..7971)
                     /gene="msrC"
                     /locus_tag="IRB70_002333"
     CDS             complement(7474..7971)
                     /gene="msrC"
                     /locus_tag="IRB70_002333"
                     /EC_number="1.8.4.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine (R)-S-oxide reductase"
                     /protein_id="HBC0632238.1"
                     /translation="MNKAEFYADLNRDFNALMAGETSFLATLANTSALLYERLTDVNW
                     AGFYLLDDDTLVLGPFQGKIACVRIPVGRGVCGTAVARNQVQRIEDVHAFDGHIACDA
                     ASNSEIVLPLVVKNQIIGVLDIDSTVFGRFTDEDEQGLRQLVAQLEKVLATTDYKKFF
                     ASVAG"
     gene            8101..9384
                     /gene="yebS"
                     /locus_tag="IRB70_002334"
     CDS             8101..9384
                     /gene="yebS"
                     /locus_tag="IRB70_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane integrity lipid transport subunit YebS"
                     /protein_id="HBC0632239.1"
                     /translation="MALNTPQITPTKKITVRAIGEELPHGDYQRCPQCDMLFSLPEIN
                     SHQSAYCPRCQAKIRDGRDWSLTRLAAMAFAMLLLMPFAWGEPLLHIWLLGIRIDANV
                     MQGIWQMTKQGDAITGSMVFFCVIGAPLILVTSIAYLWFGNRLGMNLRPVLLMLERLK
                     EWVMLDIYLVGIGVASIKVQDYAHIQAGVGLFSFVALVILTTVTLSHLNVEELWERFY
                     PQRPATRRDEKLRVCLGCHFTGYPDQRGRCPRCHIPLRLRRRHSLQKCWAALLASIVL
                     LLPANLLPISIIYLNGGRQEDTILSGIMSLASSNIAVAGIVFIASILVPFTKVIVMFT
                     LLLSIHFKCQQGLRTRILLLRMVTWIGRWSMLDLFVISLTMSLINRDQILAFTMGPAA
                     FYFGAAVILTILAVEWLDSRLLWDAHESGNARFDD"
     gene            9353..11986
                     /gene="yebT"
                     /locus_tag="IRB70_002335"
     CDS             9353..11986
                     /gene="yebT"
                     /locus_tag="IRB70_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416348.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid-binding membrane homeostasis protein YebT"
                     /protein_id="HBC0632240.1"
                     /translation="MSQETPASTTEAQIKNKRRISPFWLLPFIALMIAGWLIWDSYQD
                     RGNTVTIDFMSADGIVPGRTPVRYQGVEVGTVQDISLSDDLRKIEVKVSIKSDMKDAL
                     REETQFWLVTPKASLAGVSGLDALVGGNYIGMMPGKGKEQDHFVALDTQPKYRLDNGD
                     LMIHLQAPDLGSLSSGSLVYFRKIPVGKVYDYAINPNKQGVVIDVLIERRFTDLVKKG
                     SRFWNVSGVDANVSISGAKVKLESLAALVNGAIAFDSPEESKPAEAEDTFGLYEDLAH
                     SQRGVIIKLELPGGAGLTADSTPLMYQGLEVGQLTKLDLNPGGKVTGEITVDPSVVTL
                     LRENTRIELRNPKLSLSDANLSALLTGKTFELVPGDGEPRKEFVVVPGEKALLHEPDV
                     LTLTLTAPESYGIDAGQPLILHGVQVGQVIDRKLTSKGVTFTVAIEPQHRELVKGDSK
                     FVVNSRVDVKVGLDGVEFLGASASEWINGGIRILPGDKGEMKASYPLYANLEKALENS
                     LSDLPTTTVSLSAETLPDVQAGSVVLYRKFEVGEVITVRPRANAFDIDLHIKPEYRNL
                     LTSNSVFWAEGGAKVQLNGSGLTVQASPLSRALKGAISFDNLSGASASQRKGDKRILY
                     ASETAARAVGGQITLHAFDAGKLAVGMPIRYLGIDIGQIQTLDLITARNEVQAKAVLY
                     PEYVQTFARGGTRFSVVTPQISAAGVEHLDTILQPYINVEPGRGNPHRDFELQEATIT
                     DSRYLDGLSIIVEAPEAGSLGIGTPVLFRGLEVGTVTGMTLGTLSDRVMIAMRISKRY
                     QHLVRNNSVFWLASGYSLDFGLTGGVVKTGTFNQFIRGGIAFATPPGTPLAPKAQEGK
                     HFLLQESEPKEWREWGTALPK"
     gene            12066..13505
                     /gene="rsmF"
                     /locus_tag="IRB70_002336"
     CDS             12066..13505
                     /gene="rsmF"
                     /locus_tag="IRB70_002336"
                     /EC_number="2.1.1.178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416349.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1407)-C(5))-methyltransferase
                     RsmF"
                     /protein_id="HBC0632241.1"
                     /translation="MAQHTVYFPDAFLTQMREAMPSTLSFDDFLAACQRPLRRSIRVN
                     TLKISVADFLQLTAPYGWTLTPIPWCEEGFWIERDNEDALPLGSTAEHLSGLFYIQEA
                     SSMLPVAALFADGNAPQRVMDVAAAPGSKTTQIAARMNNEGAILANEFSASRVKVLHA
                     NISRCGISNVALTHFDGRVFGAALPEMFDAILLDAPCSGEGVVRKDPDALKNWSPESN
                     QEIAATQRELIDSAFHALRPGGTLVYSTCTLNREENEAVCLWLKETYPDAVEFLPLGD
                     LFPGANKALTEEGFLHVFPQIYDCEGFFVARLRKTQAIPVLPAPKYKVGNFPFSPVKD
                     REASQIRQAAASVGLNWDGNLRLWQRDKELWLFPVGIEALIGKVRFSRLGIKLAETHN
                     KGYRWQHEAVIALASPDNVNAFELTPQEAEEWYRGRDVYPQAAPVADDVLVTFQHQPI
                     GLAKRIGSRLKNSYPRELVRDGKLFTGNA"
     gene            13623..13859
                     /locus_tag="IRB70_002337"
     CDS             13623..13859
                     /locus_tag="IRB70_002337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707284.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1480 family protein"
                     /protein_id="HBC0632242.1"
                     /translation="MKTSVRIGAFEIDDGELHGESPGDRTLTIPCKSDPDLCMQLDAW
                     DAETSIPALLNGEHSVLYRTRYDQQSDAWIMRLA"
     gene            13964..14155
                     /locus_tag="IRB70_002338"
     CDS             13964..14155
                     /locus_tag="IRB70_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416351.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebW family protein"
                     /protein_id="HBC0632243.1"
                     /translation="MFALVLFVCYLDGGCEDIVVDVYNTEQQCLYSMSDQRIRHGGCF
                     PIEDFIDGFWRPAQEYGDF"
     gene            complement(14156..14812)
                     /gene="pphA"
                     /locus_tag="IRB70_002339"
     CDS             complement(14156..14812)
                     /gene="pphA"
                     /locus_tag="IRB70_002339"
                     /EC_number="3.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310575.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-serine/threonine phosphatase"
                     /protein_id="HBC0632244.1"
                     /translation="MKQPAPVYQRIAGHQWRHIWLSGDIHGCLEQLRRKLWHCRFDPW
                     RDLLISVGDVIDRGPQSLRCLQLLEQHWVRAVRGNHEQMAMDALASRQMSLWLMNGGD
                     WFIALADYQQKQAKTALEKCQYLPFILEVHSRTGKHVIAHADYPDDVYEWQKDVDLHQ
                     VLWSRSRLGERQKGQGITGADHFWFGHTPLRHRVDIGNLHYIDTGAVFGGELTVVQLQ
                     "
     gene            complement(15208..15549)
                     /locus_tag="IRB70_002340"
     CDS             complement(15208..15549)
                     /locus_tag="IRB70_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebY family protein"
                     /protein_id="HBC0632245.1"
                     /translation="MMKKSILAFLLLTSSAAALAAPQVITVSRFEVGKDKWAFNREEV
                     MLTCRPGNALYVINPSTLVQYPLNDIAQKEVASGKTKAQPISVIQIDDPNNPGEKMSL
                     APFIERAEKLC"
     gene            complement(15562..16434)
                     /gene="copD"
                     /locus_tag="IRB70_002341"
     CDS             complement(15562..16434)
                     /gene="copD"
                     /locus_tag="IRB70_002341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis membrane protein CopD"
                     /protein_id="HBC0632246.1"
                     /translation="MLAFTWIALRFIHFTSLMLVFGFAMYGAWLAPLTIRRLLTKRFL
                     RLQQHAAVWSLISATAMLAVQGGLMGTGWSDVFSPNIWQAVLQTQFGGVWLWQIVLAL
                     VTLIVALMQPRNMPLLLFMLTTAQFFLLAGVGHATLNEGVTAKIHQTNHAIHLICAAA
                     WFGGLLPVLWCMQLIKGRWRYQAIQALMRFSWCGHFAVIGVLASGVLNALLITGFPPT
                     LTTYWGQLLLLKAILVMIMVVIALANRYVLVPRMRQDEDRAAPWFVWMTKLEWAIGAV
                     VLVIISLLATLEPF"
     gene            complement(16438..16812)
                     /gene="yobA"
                     /locus_tag="IRB70_002342"
     CDS             complement(16438..16812)
                     /gene="yobA"
                     /locus_tag="IRB70_002342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopC domain-containing protein YobA"
                     /protein_id="HBC0632247.1"
                     /translation="MASTARSLRYALAILTTSLVTPSVWAHAHLMHQYPAANAQVTAA
                     PQAITLNFSEGVETGFSGAKITGPKNENIKTLPAKRNEQDQKQLIVPLADSLKPGTYT
                     VNWHVVSVDGHKTKGHYTFSVK"
     gene            16951..17181
                     /gene="holE"
                     /locus_tag="IRB70_002343"
     CDS             16951..17181
                     /gene="holE"
                     /locus_tag="IRB70_002343"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit theta"
                     /protein_id="HBC0632248.1"
                     /translation="MLKNLAKLDQTEMDKVNVDLAAAGVAFKERYNMPVIAEAVEREQ
                     PEHLRSWFRERLIAHRLASVNLSRLPYEPKLK"
     gene            17283..17939
                     /locus_tag="IRB70_002344"
     CDS             17283..17939
                     /locus_tag="IRB70_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon-nitrogen hydrolase family protein"
                     /protein_id="HBC0632249.1"
                     /translation="MSFWKVAAAQYEPRKTSLTEQVAHHLEFVRAAARQQCQLLVFPS
                     LSLLGCDYSRRALPAPPDLSLLDPLCYAATTWRMTIIAGLPVEYNDRFIRGIAVFAPW
                     RKTPGIYHQSHGACLGRRSRTITVVDEQPEGMDMDPTCSLFTTGQCLGEPDLLASARR
                     LQFFSHQYSIAVLMANARGNSALWDEHGRLIVRADRGSLLLVGQRSSQGWQGDIIPLR
                     "
     gene            17963..18625
                     /gene="exoX"
                     /locus_tag="IRB70_002345"
     CDS             17963..18625
                     /gene="exoX"
                     /locus_tag="IRB70_002345"
                     /EC_number="3.1.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease X"
                     /protein_id="HBC0632250.1"
                     /translation="MLRIIDTETCGLQGGIVEIASVDVIDGKIVNPMSHLVRPDRPIS
                     PQAMAIHRITEAMVADKPWIEDVIPHYYGSEWYVAHNASFDRRVLPEMPGEWICTMKL
                     ARRLWPGIKYSNMALYKTRKLNVQTPPGLHHHRALYDCYITAALLIDIMNTSGWTAEQ
                     MADITGRPSLMTTFTFGKYRGKAVSDVAERDPGYLRWLFNNLDSMSPELRLTLKHYLE
                     NT"
     gene            complement(18622..20682)
                     /gene="ptrB"
                     /locus_tag="IRB70_002346"
     CDS             complement(18622..20682)
                     /gene="ptrB"
                     /locus_tag="IRB70_002346"
                     /EC_number="3.4.21.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase B"
                     /protein_id="HBC0632251.1"
                     /translation="MLPKAARIPHAMTLHGDTRIDNYYWLRDDTRSQPEVLDYLQQEN
                     SYGHRVMASQQALQDRILKEIIDRIPQREVSAPYIKNGYRYRHIYEPGCEYAIYQRQS
                     AFSEEWDEWETLLDANKRAAHSEFYSMGGMAITPDNTIMALAEDFLSRRQYGIRFRNL
                     ETGNWYPELLDNVEPSFVWANDSWTFYYVRKHPVTLLPYQVWRHAIGTPASQDKLIYE
                     EKDDTYYVSLHKTTSKHYVVIHLASATTSEVRLLDAEMADAEPFVFLPRRKDHEYNLD
                     HYQHRFYLRSNRHGKNFGLYRTRMRDEQQWEELIPPRDNIMLEGFTLFTDWLVVEERQ
                     RGLTSLRQINRKTREVIGIAFDDPAYVTWIAYNPEPETARLRYGYSSMTTPDTLFELD
                     MDTGERRVLKQTEVPGFDAANYRSEHLWIVARDGVEVPVSLVYHRKHFRKGHNPLLVY
                     GYGSYGASIDADFSFSRLSLLDRGFVYAIVHVRGGGELGQQWYEDGKFLKKKNTFNDY
                     LDACDALLKLGYGSPSLCYAMGGSAGGMLMGVAINQRPELFHGVIAQVPFVDVVTTML
                     DESIPLTTGEFEEWGNPQDPQYYEYMKSYSPYDNVTAQAYPHLLVTTGLHDSQVQYWE
                     PAKWVAKLRELKTDNHLLLLCTDMDSGHGGKSGRFKSYEGVAMEYAFLVALAQGTLPA
                     TPED"
     gene            complement(20891..21550)
                     /locus_tag="IRB70_002347"
     CDS             complement(20891..21550)
                     /locus_tag="IRB70_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance TerB family protein"
                     /protein_id="HBC0632252.1"
                     /translation="MANWLNQLQSLLGQSSSSVSSSADQGLGKLLVPGALGGLAGLLV
                     ANKSARKLLTKYGTNALLVGGGAVAGTVLWNKYKDKIRAAHQDEPQFGAQSTPLDERT
                     ERLILALVFAAKSDGHIDARERAAIDQQLREAGVEEQGRVLIEQAIEQPLDPQRLATG
                     VRNEEEALEIYFLSCAAIDIDHFMERSYLNALGDALKIPQDVREGIERDLEQQKRTLA
                     E"
     gene            complement(21876..22232)
                     /locus_tag="IRB70_002348"
     CDS             complement(21876..22232)
                     /locus_tag="IRB70_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310584.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YebF"
                     /protein_id="HBC0632253.1"
                     /translation="MKKRGAFLGLLLVSACASVFAANNETSKSVTFPKCEGLDAAGIA
                     ASVKRDYQQNRVARWADDQKIVGQADPVAWVSLQDIQGKDDKWSVPLTVRGKSADIHY
                     QVSVDCKAGMAEYQRR"
     gene            complement(22299..22589)
                     /gene="yebG"
                     /locus_tag="IRB70_002349"
     CDS             complement(22299..22589)
                     /gene="yebG"
                     /locus_tag="IRB70_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA damage-inducible protein YebG"
                     /protein_id="HBC0632254.1"
                     /translation="MAVEVKYVVIREGEEKMSFTSKKEADAYDKMLDTADLLDTWLTN
                     SPVQMEDEQREALSLWLAEQKDVLSTILKTGKLPSPQVVGAESEEEDASHAA"
     gene            22723..23901
                     /gene="purT"
                     /locus_tag="IRB70_002350"
     CDS             22723..23901
                     /gene="purT"
                     /locus_tag="IRB70_002350"
                     /EC_number="2.1.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent phosphoribosylglycinamide
                     formyltransferase"
                     /protein_id="HBC0632255.1"
                     /translation="MTLLGTALRPAATRVMLLGSGELGKEVAIECQRLGVEVIAVDRY
                     ADAPAMHVAHRSHVINMLDGDALRRVVELEKPHYIVPEIEAIATDMLIQLEEEGLNVV
                     PCARATKLTMNREGIRRLAAEDLQLPTSTYRFADNENLFREAVADIGYPCIVKPVMSS
                     SGKGQTFIRSAEQLAHAWEYAQQGGRAGAGRVIVEGVVKFDFEITLLTVSAVDGVHFC
                     APVGHRQEDGDYRESWQPQQMSPLALERAQEIARKVVLALGGYGLFGVELFVCGDEVI
                     FSEVSPRPHDTGMVTLISQDLSEFALHVRAFLGLPVGGIRQYGPAASAVILPQLTSQN
                     VTFDNVQNAVGADLQIRLFGKPEIDGSRRLGVALATAESVVDAIERAKHAAGQVKVQG
                     "
     gene            complement(23957..24598)
                     /gene="kdgA"
                     /locus_tag="IRB70_002351"
                     /gene_synonym="eda"
     CDS             complement(23957..24598)
                     /gene="kdgA"
                     /locus_tag="IRB70_002351"
                     /gene_synonym="eda"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBC0632256.1"
                     /translation="MKNWKTSAESILTTGPVVPVIVVKKLEHAVPMAKALVAGGVRVL
                     EVTLRTECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQFAISPGLTEPLLK
                     AATEGTIPLIPGISTVSELMLGMDYGLKEFKFFPAEANGGVKALQAIAGPFSQVRFCP
                     TGGISPANYRDYLALKSVLCIGGSWLVPADALEAGDYDRITKLAREAVEGAKL"
     gene            complement(24635..26446)
                     /gene="edd"
                     /locus_tag="IRB70_002352"
     CDS             complement(24635..26446)
                     /gene="edd"
                     /locus_tag="IRB70_002352"
                     /EC_number="4.2.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphogluconate dehydratase"
                     /protein_id="HBC0632257.1"
                     /translation="MNPQLLRVTNRIIERSRETRSAYLARIEQAKTSTVHRSQLACGN
                     LAHGFAACQPEDKASLKSMLRNNIAIITSYNDMLSAHQPYEHYPEIIRKALHEANAVG
                     QVAGGVPAMCDGVTQGQDGMELSLLSREVIAMSAAVGLSHNMFDGALFLGVCDKIVPG
                     LTMAALSFGHLPAVFVPSGPMASGLPNKEKVRIRQLYAEGKVDRMALLESEAASYHAP
                     GTCTFYGTANTNQMVVEFMGMQLPGSSFVHPDSPLRDALTAAAARQVTRMTGNGNEWM
                     PIGKMIDEKVVVNGIVALLATGGSTNHTMHLVAMARAAGIQINWDDFSDLSDVVPLMA
                     RLYPNGPADINHFQAAGGVPVLVRELLKAGLLHEDVNTVAGFGLSRYTLEPWLNNGEL
                     DWREGAEKSLDSNVIASFEQPFSHHGGTKVLSGNLGRAVMKTSAVPVENQVIEAPAVV
                     FESQHDVMPAFEAGLLDRDCVVVVRHQGPKANGMPELHKLMPPLGVLLDRCFKIALVT
                     DGRLSGASGKVPSAIHVTPEAYDGGLLAKVRDGDIIRVNGQTGELTLLVDEAELAARE
                     PHIPDLSASRVGTGRELFSALREKLSGAEQGATCITF"
     gene            complement(26681..28156)
                     /gene="zwf"
                     /locus_tag="IRB70_002353"
     CDS             complement(26681..28156)
                     /gene="zwf"
                     /locus_tag="IRB70_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBC0632258.1"
                     /translation="MAVTQTAQACDLVIFGAKGDLARRKLLPSLYQLEKAGQLNPDTR
                     IIGVGRADWDKAAYTKVVREALETFMKETIDEGLWDTLSARLDFCNLDVNDTAAFSRL
                     GAMLDQKNRITINYFAMPPSTFGAICKGLGEAKLNAKPARVVMEKPLGTSLATSQEIN
                     DQVGEYFEECQVYRIDHYLGKETVLNLLALRFANSLFVNNWDNRTIDHVEITVAEEVG
                     IEGRWGYFDKAGQMRDMIQNHLLQILCMIAMSPPSDLSADSIRDEKVKVLKSLRRIDR
                     SNVREKTVRGQYTAGFAQGKKVPGYLEEEGANKSSNTETFVAIRVDIDNWRWAGVPFY
                     LRTGKRLPTKCSEVVVYFKTPELNLFKESWQDLPQNKLTIRLQPDEGVDIQVLNKVPG
                     LDHKHNLQITKLDLSYSETFNQTHLADAYERLLLETMRGIQALFVRRDEVEEAWKWVD
                     SITEAWAMDNDAPKPYQAGTWGPVASVAMITRDGRSWNEFE"
     gene            28494..29363
                     /gene="hexR"
                     /locus_tag="IRB70_002354"
                     /gene_synonym="yebK"
     CDS             28494..29363
                     /gene="hexR"
                     /locus_tag="IRB70_002354"
                     /gene_synonym="yebK"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator HexR"
                     /protein_id="HBC0632259.1"
                     /translation="MNMLEKIQSQLEHLSKSERKVAEVILASPDNAIHSSIAALALEA
                     NVSEPTVNRFCRSMDTRGFPDFKLHLAQSLANGTPYVNRNVNEDDSVESYTGKIFESA
                     MATLDHVRHSLDKSAINRAVDLLTQAKKIAFFGLGSSAAVAHDAMNKFFRFNVPVVYS
                     DDIVLQRMSCMNCSDGDVVVLISHTGRTKNLVELAQLARENDAMVIALTSAGTPLARE
                     ATLAITLDVPEDTDIYMPMVSRLAQLTVIDVLATGFTLRRGAKFRDNLKRVKEALKES
                     RFDKQLLNLSDDR"
     gene            29491..30933
                     /gene="pyk"
                     /locus_tag="IRB70_002355"
     CDS             29491..30933
                     /gene="pyk"
                     /locus_tag="IRB70_002355"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBC0632260.1"
                     /translation="MSRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSP
                     EDHKMRADKVREIAAKLGRHVAILGDLQGPKIRVSTFKEGKVFLNIGDKFLLDANLGK
                     GEGDKEKVGIDYKGLPADVVPGDILLLDDGRVQLKVLEVQGMKVFTEVTVGGPLSNNK
                     GINKLGGGLSAEALTEKDKADIKTAALIGVDYLAVSFPRCGEDLNYARRLARDAGCDA
                     KIVAKVERAEAVCSQDAMDDIILASDVVMVARGDLGVEIGDPELVGIQKALIRRARQL
                     NRAVITATQMMESMITNPMPTRAEVMDVANAVLDGTDAVMLSAETAAGQYPSETVAAM
                     ARVCLGAEKIPSINVSKHRLDVQFDNVEEAIAMSAMYAANHLKGVTAIITMTESGRTA
                     LMTSRISSGLPIFAMSRHERTLNLTALYRGVTPVHFDSANDGVAAASEAVNLLRDKGY
                     LMSGDLVIVTQGDVMSTVGSTNTTRILTVE"
     gene            complement(31065..32036)
                     /gene="lpxM"
                     /locus_tag="IRB70_002356"
                     /gene_synonym="msbB"
     CDS             complement(31065..32036)
                     /gene="lpxM"
                     /locus_tag="IRB70_002356"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416369.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HBC0632261.1"
                     /translation="METKKNNSEYIPEFDKSFRHPRYWGAWLGVAAMAGIALTPPKFR
                     DPILARLGRFAGRLGKSSRRRALINLSLCFPERSEAEREAIVDEMFATAPQAMAMMAE
                     LAIRGPEKIQPRVDWQGLEIIEEMRRNNEKVIFLVPHGWAVDIPAMLMASQGQKMAAM
                     FHNQGNPVFDYVWNTVRRRFGGRLHARNDGIKPFIQSVRQGYWGYYLPDQDHGPEHSE
                     FVDFFATYKATLPAIGRLMKVCRARVVPLFPIYDGKTHRLTIQVRPPMDDLLEADDHT
                     IARRMNEEVEIFVGPRPEQYTWILKLLKTRKPGEIQPYKRKDLYPIK"
     gene            complement(32156..33478)
                     /gene="mepM"
                     /locus_tag="IRB70_002357"
     CDS             complement(32156..33478)
                     /gene="mepM"
                     /locus_tag="IRB70_002357"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein DD-endopeptidase MepM"
                     /protein_id="HBC0632262.1"
                     /translation="MQQIARSVALAFNNLPRPHRVMLGSLTVLTLAVAVWRPYVYHRD
                     ATPIVKTIELEQNEIRSLLPEASEPIDQAAQEDEAIPQDELDDKIAGEAGVHEYVVST
                     GDTLSSILNQYGIDMGDITQLAAADKELRNLKIGQQLSWTLTADGELQRLTWEVSRRE
                     TRTYDRTAANGFKMTSEMQQGEWVNNLLKGTVGGSFVASARNAGLTSAEVSAVIKAMQ
                     WQMDFRKLKKGDEFAVLMSREMLDGKREQSQLLGVRLRSEGKDYYAIRAEDGKFYDRN
                     GTGLAKGFLRFPTAKQFRISSNFNPRRTNPVTGRVAPHRGVDFAMPQGTPVLSVGDGE
                     VVVAKRSGAAGYYVAIRHGRSYTTRYMHLRKILVKPGQKVKRGDRIALSGNTGRSTGP
                     HLHYEVWINQQAVNPLTAKLPRTEGLTGSDRREFLAQAKEIVPQLRFD"
     gene            complement(33494..34426)
                     /gene="znuA"
                     /locus_tag="IRB70_002358"
     CDS             complement(33494..34426)
                     /gene="znuA"
                     /locus_tag="IRB70_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416371.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     ZnuA"
                     /protein_id="HBC0632263.1"
                     /translation="MLHKKTLLFAALSAALWGGATQAADAAVVASLKPVGFIASAIAD
                     GVTETQVLLPDGASEHDYSLRPSDVKRLQNADLVVWVGPEMEAFMQKPVSKLPEAKQV
                     TIAQLEDVKPLLMKSIHDDDDDHDHAEKSDEDHHHGDFNMHLWLSPEIARATAVAIHG
                     KLVELMPQSRAKLDANLKDFEAQLASTETQVGNELAPLKGKGYFVFHDAYGYFEKQFG
                     LTPLGHFTVNPEIQPGAQRLHEIRTQLVEQKATCVFAEPQFRPAVVESVARGTSVRMG
                     TLDPLGTNIKLGKTSYSEFLNQLANQYASCLKGD"
     gene            34505..35260
                     /gene="znuC"
                     /locus_tag="IRB70_002359"
     CDS             34505..35260
                     /gene="znuC"
                     /locus_tag="IRB70_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter ATP-binding protein ZnuC"
                     /protein_id="HBC0632264.1"
                     /translation="MTSLVSLENVSVSFGQRRVLSDVSLELKPGKILTLLGPNGAGKS
                     TLVRVVLGLVTPDEGVIKRNGKLRIGYVPQKLYLDTTLPLTVNRFLRLRPGTHKEDIL
                     PALKRVQAGHLINAPMQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQVALY
                     DLIGQLRRELDCGVLMVSHDLHLVMAKTDEVLCLNHHICCSGTPEVVSLHPEFISMFG
                     PRGAEQLGIYRHHHNHRHDLQGRIVLRRGNDRS"
     gene            35257..36042
                     /gene="znuB"
                     /locus_tag="IRB70_002360"
     CDS             35257..36042
                     /gene="znuB"
                     /locus_tag="IRB70_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter permease subunit ZnuB"
                     /protein_id="HBC0632265.1"
                     /translation="MIELLFPGWLAGIMLACAAGPLGSFVVWRRMSYFGDTLAHASLL
                     GVAFGLLLDVNPFYAVIAVTLLLAGGLVWLEKRPQLAIDTLLGIMAHSALSLGLVVVS
                     LMSNIRVDLMAYLFGDLLAVTPEDLISIAIGVVIVVAILFWQWRNLLSMTISPDLAFV
                     DGVKLQRVKLLLMLVTALTIGVAMKFVGALIITSLLIIPAATARRFARTPEQMAGVAV
                     LVGMVAVTGGLTFSAVYDTPAGPSVVLCAALLFILSMMKKQAS"
     gene            complement(36383..37393)
                     /gene="ruvB"
                     /locus_tag="IRB70_002361"
     CDS             complement(36383..37393)
                     /gene="ruvB"
                     /locus_tag="IRB70_002361"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBC0632266.1"
                     /translation="MIEADRLISAGTTLPEDVADRAIRPKLLEEYVGQPQVRSQMEIF
                     IKAAKLRGDALDHLLIFGPPGLGKTTLANIVANEMGVNLRTTSGPVLEKAGDLAAMLT
                     NLEPHDVLFIDEIHRLSPVVEEVLYPAMEDYQLDIMIGEGPAARSIKIDLPPFTLIGA
                     TTRAGSLTSPLRDRFGIVQRLEFYQVPDLQYIVSRSARFMGLEMSDDGALEVARRARG
                     TPRIANRLLRRVRDFAEVKHDGTISADIAAQALDMLNVDAEGFDYMDRKLLLAVIDKF
                     FGGPVGLDNLAAAIGEERETIEDVLEPYLIQQGFLQRTPRGRMATTRAWNHFGITPPE
                     MP"
     gene            complement(37402..38013)
                     /gene="ruvA"
                     /locus_tag="IRB70_002362"
     CDS             complement(37402..38013)
                     /gene="ruvA"
                     /locus_tag="IRB70_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012131997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBC0632267.1"
                     /translation="MIGRLRGIIIEKQPPLVLIEVGGVGYEVHMPMTCFYELPEAGQE
                     AIVFTHFVVREDAQLLYGFNNKQERTLFKELIKTNGVGPKLALAILSGMSAQQFVNAV
                     EREEVGALVKLPGIGKKTAERLIVEMKDRFKGLHGDLFTPAADLVLTSPASPATNDAE
                     QEAVAALVALGYKPQEASRMVSKIARPDASSETLIREALRAAL"
     gene            complement(38152..38217)
                     /gene="yobI"
                     /locus_tag="IRB70_002363"
     CDS             complement(38152..38217)
                     /gene="yobI"
                     /locus_tag="IRB70_002363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response small protein YobI"
                     /protein_id="HBC0632268.1"
                     /translation="MYIFITHFFTEYVILKYLLPK"
BASE COUNT         9174 a         9863 c         9409 g         9784 t
ORIGIN      
        1 agaccagagt tttaatttga agcagttgca ccatgacagt gcgtataatc aggatgaatt
       61 gagtaaccct tcaacgacgg ggttactcaa gattgaggaa ggattatcgt tcggcgacca
      121 gacgaataat atcttcgtct tcaaccgatt tttgactctc aacggtcttt ttatctgctt
      181 tctcaggttc gtttgcttcg cacaaacgac gtaacagagc attttgacgt ttttgctgat
      241 ccagcaacgc ctcaagcagt tcaatctgtt cgttagtccg tgaactggca cgattgataa
      301 aaaaccacaa gataagcccg ataaaaagaa ccaccaccga tacaaccaaa gacgcaatgt
      361 tcatcacgcc tgaatttaca acttcgttca tttcaccacc tctgagtaga ggcgctattc
      421 taccactgct ggagaggaag aaaatctagt gctgaaaaaa tgatatcacc acgggataaa
      481 ctggttaatg gcacaaattc cgctgaaaaa ttgtacatcc tgatcgcaca tcatgttgaa
      541 tacctgcgcc caaagcagca agcaagccaa caccacgaca accagaacga cccatcgaaa
      601 ctttttcact ccaatctccg tttcacctac cttatgtcat taaactagca tgcgttagtt
      661 aaacagcgcc taactatgtc gatattcgtg ctttttcaga atgagtcgct tgcttcagcg
      721 catattgccg ctacgattaa gcgaacataa aaagagaaga ggttgtaatg cgattcatca
      781 ttcgcacagt tatgctgata gcactggtat ggataggatt attactcagc ggatatggcg
      841 ttttgattgg aagcaaagag aatgccgcgg gattaggttt gcaatgtacc tatctgaccg
      901 ccagaggcac cagcacggta caatacctgc acactaaaag tggttttctg gggataacag
      961 attgcccgtt gttacgtaaa agcaatattg tggtcgataa tggttaaggg taataaataa
     1021 ccagattctc actcatgagt aaaatattct tatcgcaagt gcgtttaata taacgccacc
     1081 ttcaacttta tttttctcat gctaaataaa gaacctgtct gtttgatatt cagacaggtt
     1141 cttactctca tcagaacgga tagtcgtgat aacccatttg ggcagaaatt ttgcgcgccg
     1201 cggtatgcaa cattgcaaca tattcctgta aacgctcttc agagaaacgt aacgtcggga
     1261 aggagatgct caaaccggca atgaccacgc caaagcgatc aaataccgga accgcaatgc
     1321 atcgcagccc ttcttcctgc tcttcattat cttcgccata cccctgctcg cgcacctggt
     1381 ccagaacggg taataacgct tctgtactgg tgatggtccg ctcggtactg cgtttatact
     1441 ccacgccctc aagaatttgc ttcacctcat cgcgatcgcg ccatgccagc agtaccttac
     1501 caatcgcggt gctgtacagc ggattacgac gcccaatccg tgaatacatg cgcaaattgt
     1561 acattgagtc aattttgtgg atgtaaacaa tactgtcttc gtccagtgcg ccgaggtgga
     1621 tagtttcttt ggtcaggcgg gagatctcac gcatctggat atctgcgcta cgaattaaat
     1681 cgacgttttg caacgcgcga gcgcccagtt caaacaattt cagggtcagc gaatatttct
     1741 ccgactcccc ttcctgcgcc acataaccta aggttttcat ggtctgtaaa aagcgataaa
     1801 cggtgctttt tgacatcatg acgcgctgcg acaactcggt tatccctatt tcgcgctctt
     1861 cacccagcgc ctgcaaaatg ccaaaaactt ttagcacgga agatacagaa tcaggctgtt
     1921 tatccagatc tgcgttagcc atttatcacc tcattgcgag tgttttataa aaatcagaac
     1981 tgttttttat tataatttcg cacctgggtg gtcgcaatcc atcttttgcc ggttagttac
     2041 aattctgcga catccaccgt gaatatcagt gctagaatca tacccctgtt gattattcac
     2101 caaagatata aaattcctat gccaaaagtt caggccgacg gcctgccatt gccccagcga
     2161 tacggtgcga tattaaccat tgtgattggt atttcgatgg ctgtccttga cggcgcaatc
     2221 gccaacgtcg ccctgccaac aatcgccacg gaccttcatg ccacgccagc cagttccatc
     2281 tgggtagtga acgcctatca aatcgccatt gtcatctccc tgctctcgtt ttcgtttctg
     2341 ggcgatatgt ttggctatcg acgtatttat aaatgcggtc tggtcgtttt tctgttgtct
     2401 tcactgttct gcgccctttc tgattcgctg caaatgctca cccttgcgcg tgtcatacaa
     2461 ggtttcggcg gtgcagcgtt gatgagcgtt aataccgcac ttatccgcct gatctatcca
     2521 caacgttttc tgggtagagg gatgggcata aactcgttta ttgttgccgt ctcttctgct
     2581 gccgggccga caattgctgc agcaatcctc tccatcgcat cctggaaatg gttattttta
     2641 atcaacgtac cgttgggtat tatcgccctg cttctggcga tgcgttttct accacccaat
     2701 ggttctcgcg ccagtaaacc ccgtttcgac ctgcccagcg ccgtgatgaa cgcgttaacc
     2761 ttcggcctgc ttattactgc attgagtggt ttcgctcagg ggcaatcgct gacattgatt
     2821 ggtgcggaac tggtggtaat ggttgtcgtt ggtattttct ttattcgccg ccagctttct
     2881 cttcccgtac cgctgctacc ggtggattta ctgcgtatcc cgctgttttc actttctatt
     2941 tgcacatctg tttgctcttt ctgcgcacaa atgctggcaa tggtttccct tcccttttac
     3001 ctgcaaaccg tgctcgggcg tagtgaagtc gaaacaggtt tacttctgac accgtggccg
     3061 ttagcaacaa tggtgatggc tccgctggca ggctatttga ttgaacgcgt acatgcagga
     3121 ttgctgggtg ctttagggtt attcatcatg gctgcggggc ttttttccct ggttctgctg
     3181 ccagcgtcac ctgcggatat caatattatc tggccgatga tcttatgtgg cgctggattt
     3241 ggcttattcc agtcacccaa taaccacacc attataacct ccgctccgcg cgaacgtagc
     3301 ggtggggcca gtggcatgtt agggacggct cgtctattgg gtcagagtag cggcgcggca
     3361 ctggtggcgc taatgctaaa tcagtttggt gataatggta cgcacgtctc gctgatggct
     3421 gcggctattc tggcagtgat tgctgcctgt gtcagtggtt tacgtatcac tcagccacga
     3481 tccatggcat aaaaaaagcg cgtcgatcag gacgcgcttt ttagtattta cttcatatta
     3541 cttcaggtat tcacccgtac gcagagcttc aatacgttta tccagcggcg ggtgagtcat
     3601 gaacaactca ctgagcgatt tcgacttacc gttaatacag aaagccatca tgctggttgc
     3661 ttcttgcggt tcatagctgg ttttcaggcg ctgcagcgcg gcaatcattt tctcgcgacc
     3721 aaccagtttt gccgaaccgg catcagcatg gaattcacga tgacgcgaga accacatggt
     3781 gataatgctc gccagaatac caaacaccag ttccagaacc gttgcaaccg caaagtagat
     3841 cagcgggttg ccgttgctct cttcaccttc atcacgattt ccgcccataa aacccgcggc
     3901 aagctgcgcc agaatacggg aaataaagat aacgaaggtg ttcaccacgc cctgaatcag
     3961 cgtcatggtg accatatcac cattggcgat gtggctgatt tcgtgagcaa ttaccgcctc
     4021 ggcttcatcc ggactcatgt tctgcagcaa accggtgctg acagcaacca gagaggcatc
     4081 acggcgcgca ccggttgcaa aagcgttgat gtccggcgca tggtagatag ccacttgcgg
     4141 catagcgatc cccgcctgac gagcctgggt tgctactgta ttgaccagcc aacgttccct
     4201 ttcgttacgc ggttgctcga tcacttcccc gccaacagat cgtaatgcca tccatttgga
     4261 catcagaagc gaaacgaagg aaccaccaaa accgaacagc aaggccatga tcatcagccc
     4321 ctgaacgctg ctcgactgta tccctgtcag gctcagtacc agcccgaaaa cgaccattac
     4381 ggccaggttc gttagcagga agagcgcgat tcgcatcata attttctttt tacctcagtt
     4441 taacaaaacg caatatgcga tacccacatc gtatgggtta cgcgactatt ttcaagtctg
     4501 gatagtgcgt aagtcaccag aaagacacaa ctttacattt tgtagcatct gatttacggc
     4561 atcttgccgc tgttaaaaaa tcaggcacaa tttcttgtgc ctgattgata ttacttgacg
     4621 ggagcgggtt gttccgcggg tctggctttt tcaagcttcg ccagattgag tgcgatattc
     4681 accgtctcat ccagataagg atctggctcc tggtaatctt tcggtagatc atccagtttc
     4741 ttcaactccg gtttaccttc gcgtttaaag cgttcgttca aacgcgccag acgcgtcgca
     4801 tcatcttcat tattctcttt ctcacgcaca gcgtaattca gagaaacgat attgcgcttg
     4861 tccttcatag cgttgaagcg tgcgatatcc ttcatgatgt tctggaactc aggatctttc
     4921 gcgatacgcg cattatgttc cttcagcagc tccggttcaa aggccgttaa atctcctgat
     4981 ttcacataag tcgcggcatc aatgctatcc cacggcagcg cgttatcttc gaatttctca
     5041 cccgtttccg tttcttcatt acccgtcggc atgatgatgt ctggcgttac gcctttacgt
     5101 tgcgtactgc cgccgttaac gcgatagaat ttctggatcg tgtactgcac agatcccagc
     5161 gctggccatt caggacgtaa catctgatcg tagatacggt tcaatgaacg gtattgctga
     5221 acggtgcctt taccaaacgt cggttcaccc acaaccagcg cacgaccgta atcctgcatt
     5281 gccgcggcaa agatttctga agccgaagca ctgaaacggt caaccagtac caccagcggg
     5341 cctttataga agacctgtcc gtcggtatcg ctgtcttcac gaactttacc gttgttatca
     5401 cggacctgaa caatcgggcc ggatggaata aacagaccgg agagcgatac cgcttcggtc
     5461 agcgccccac caccattgct acgcaggtcg atgatgacgc tgctgacatt ctgtttttcc
     5521 agtttctgca gttgtacttt gacatcatct gtcaaaccca catagaagcc aggaatatcc
     5581 agcacgccga ctttctcttt accaacggtc ttcaccgaca ttttaaccgc gcggtcttcg
     5641 agacgaatac gttcacgggt caacgttaca gtacgggtct tggtcccttt accagcaggt
     5701 aaaatttcca gacgaacttt actgcccttc ggccctttaa ttaaggcaac cacatcatca
     5761 agacgccagc caatcacgtc aaccatcggc ttgcctgttt gacccacacc gacaattttg
     5821 tcaccaacgc tgatagcttt gctcttcgct gccggacctc ctgccaccat cgaattgata
     5881 acggtgtagt catcatccat ttgcagcact gcgccaatac cttccagcga caaactcatt
     5941 tcagtgttga actgttcggt attacgcggg gaaagatagt tggtatgcgg gtcgatttca
     6001 cgtgcaaacg ccgtcattgc cagcgagaaa acatcttcgc tgttggtttg cgccagacga
     6061 cgaatggcaa atttgtagcg gcgagtcagg gtttcacgaa tttctttatc cgtttttcct
     6121 gccagcttca agcttaactc gtcgaatttg actttactgt cccacagcgc gttcaactca
     6181 gcctcgtttt tcggccaggg cgctttgctg cggtcaaggt tataagtgtc gttgccggtg
     6241 aaatccatcg gcttttccag taccgacaaa gcgtactggt aacgttcaaa acgacgcttt
     6301 tgcgccagat tgtagagatc gtagaaaacg tcgagtttgc ctgaacgcag ttcatcgcct
     6361 aactcggttt tctttttcgc gaactgttca acatcgcttg ccaacagcac gttgtggctg
     6421 taatcgagca gattcaggta gcggtcaaag attttggccg aaaatgcctg atcgaggtcg
     6481 aactggcgat aatgagaacg ggtgaagcgc gacgttacgc gctcacttac cgtcgcatgc
     6541 tgcgtctctt cctttaatac cggaatttga tcagcacgcg tgatatcttc tacagcgaag
     6601 gtctggcctg ctattgcaag caggctagct aacgcggtaa gcctaaaaaa catgttcatg
     6661 cctggcccgg cctccgtttc agaacaccag gtgttctgcg cgcacaatca aagacatacc
     6721 cgaattcagc tggacgcgga cgccgtcttt ggtgatttct aatacggtgg catccatcgc
     6781 gttttgaccc gctttcacct ttagggcttg tccgacagtc agagctgaaa tgtcagaaac
     6841 cggggtgtgc tgttcttcgc gaggtgcttt tactgttttt ggcgctttct ctaccggctt
     6901 ttgcgaacga ggtttacgtt cagcgccttc tttgcggcgt ggcgaggtcg gacgtggctt
     6961 gcgttcgcgg cgcggtgcgt cttctttctc accagcagct gcggcagctt cgcgtttttt
     7021 cgcttgctgt tcagcacgct gtgcctgaac acgcgctttc gcttcttcaa gctgcttgcg
     7081 agcatgctcg acatgttgct cgtccagctc accgcatggg ttgccgtcaa gatcgacacg
     7141 cgttgcgccg ggtttaacac cgtaaaggta acgccagctc gaagtgtaga gacgtaaagc
     7201 ggatcgcaat tgcgttttgc tcaggttcat ttccccggca acacgatcga ccaaatcctg
     7261 aaaaataccg attttcagcg gacgcgcttc accttccgca ctgaaacagt ggggaaaacg
     7321 ttcggccaga aacgcgatta cttctttact gctattcaac ttaggttgat tttccatgaa
     7381 atttcctgat tacaacggac gtagccaaca agcgcaggca tgaacaggcg tcattataat
     7441 gacgctatca gtaaatgcta cgttatccgt tgattatcct gcgacgctcg caaagaattt
     7501 tttgtaatcc gtcgttgcaa gcaccttttc aagctgtgcc acaagctgac gtaagccttg
     7561 ctcgtcctcg tctgtaaagc gaccgaagac ggtactgtcg atgtcgagaa caccaataat
     7621 ctgatttttc accaccagtg gcagaacaat ttcagaatta ctcgccgcat cacaggcaat
     7681 atgcccgtca aacgcgtgaa catcctcgat acgctgcact tgattgcggg caaccgcagt
     7741 gccgcatacg ccgcgcccaa cgggtatccg gacacaggca attttgccct gaaatggtcc
     7801 gagcaccagt gtatcgtcgt caagcaaata aaaacctgcc cagtttacgt cagtgagacg
     7861 ctcatataac aacgcactgg tgttcgcaag cgttgccaga aaactggttt ctcccgccat
     7921 cagcgcgtta aagtcgcgat ttaaatccgc gtaaaattct gctttgttca ttatataatc
     7981 acttggttgt cttacctgga actgccagcc tattaaaata agcattaaat gcgttaatgc
     8041 tcaagatcat tcccatcatg ggttaagatt aatgttaatt cttattacat ttggcacgtc
     8101 atggctctta acacaccaca aattacgccg acaaaaaaga taacagtgag ggctatcggt
     8161 gaggaactgc cgcatggtga ttaccaacgt tgcccgcaat gtgacatgct gtttagcctg
     8221 cccgagataa attctcatca aagtgcctat tgtccgcgct gtcaggcaaa aattcgtgac
     8281 gggcgcgact ggtcgctaac gcgcctggcg gcaatggcgt tcgctatgct gttgttgatg
     8341 ccgtttgcct ggggcgaacc gctgttgcat atctggctgt taggcattcg tattgacgcc
     8401 aacgttatgc aaggcatctg gcaaatgacc aaacagggcg atgcgataac ggggtcgatg
     8461 gtcttttttt gcgttattgg tgcccccctc attctggtga cctccatagc ttatttatgg
     8521 tttggtaacc gactgggaat gaatttacgt ccggtactac tgatgcttga acgacttaaa
     8581 gagtgggtaa tgctggatat ctacctggtc ggcattggcg ttgcttctat aaaggtacag
     8641 gattatgccc atatccaggc gggtgtcggc ttgttctctt ttgtggcgtt ggtgatttta
     8701 acgacggtga cgttgtcaca tcttaatgtc gaagaactgt gggagcgatt ttatccgcag
     8761 cgccccgcta cgcgaaggga cgagaaactc cgtgtctgtc ttgggtgtca ttttaccggc
     8821 tatcctgatc agcgtggtcg ctgcccgcgt tgccatatcc cgctacgcct gcgtcgccgt
     8881 catagtctgc aaaaatgctg ggcggcgctg ttagcgtcaa tcgttttgtt gttacctgcc
     8941 aacctgttgc ctatctctat catttatctg aatggtggtc ggcaggaaga tacgattctt
     9001 tccggaatta tgtcgctggc aagtagcaac attgcggttg cgggaatcgt gtttatcgcc
     9061 agtattctgg taccgtttac taaagtgatc gtcatgttca ctttactgtt gagtattcat
     9121 tttaaatgcc agcaaggttt acgcacacgc attctgttac tgcggatggt gacctggatt
     9181 ggtcgctggt cgatgctcga cctgtttgtc atatctttaa ccatgtcgct gattaatcgc
     9241 gatcagatcc tcgcttttac tatgggaccg gctgcgtttt atttcggcgc agcggtaatt
     9301 ttgactattc ttgctgtgga atggctggac agccgcttac tttgggatgc acatgagtca
     9361 ggaaacgccc gcttcgacga ctgaagcgca gattaaaaat aaacgccgta tctcaccttt
     9421 ctggctgctg ccgttcatcg cgctaatgat tgccggttgg ctgatttggg acagttatca
     9481 ggaccggggt aataccgtca ccatcgactt tatgtcggcg gatggtattg tcccgggccg
     9541 cacccctgtt cgttatcagg gcgttgaagt cggaactgtg caggatatca gcctcagcga
     9601 cgatcttcgt aagattgaag tcaaggtcag catcaagtct gatatgaaag atgcgctgcg
     9661 cgaagagaca cagttctggc tggtgacgcc aaaggcctcg ctggcaggtg tctccgggct
     9721 ggacgccctc gtcggtggta attatatcgg catgatgccg ggtaaaggta aagagcagga
     9781 tcactttgtc gcactcgaca cccaaccgaa atatcggctg gacaatggcg atctgatgat
     9841 ccacctgcaa gcccccgatc tcggttcact gagcagtggt tcattggtct atttccgcaa
     9901 gatcccggtg ggtaaagtct acgactatgc catcaatccc aacaagcaag gcgtggtgat
     9961 tgatgtcctg atcgagcggc gttttaccga tctggtgaaa aaaggtagcc gtttctggaa
    10021 cgtttccggc gttgatgcca acgtcagtat cagtggcgcg aaggtgaaac tggaaagtct
    10081 ggcggcactg gttaacggtg cgattgcctt cgattcacct gaagagtcga aacctgccga
    10141 ggcggaagat acctttggtc tgtatgaaga cctggcccat agccaacgtg gcgtaataat
    10201 aaaactggaa ctgccaggcg gtgccggatt aaccgccgac tcgacgccgt taatgtatca
    10261 ggggctggaa gtcggacagc taactaaact ggatttaaat cctggtggta aagtcactgg
    10321 ggaaataacc gttgatccca gcgtcgttac cctgcttcgt gaaaataccc gcatcgaatt
    10381 acgcaacccg aaattatccc ttagcgatgc caatctcagc gccctgctga ctggcaaaac
    10441 cttcgagttg gtgcccggcg atggcgagcc acgcaaagag ttcgttgttg tgccaggcga
    10501 aaaagcactg ctgcatgaac ctgatgttct gacactgacc ctgacagcac cggaaagtta
    10561 cggtattgat gctggtcagc cgctcattct tcacggcgtg caggtaggcc aggttattga
    10621 tcgtaaactc accagcaaag gcgtcacctt taccgtcgcc atcgagcctc agcatcgaga
    10681 actggtaaaa ggcgatagca aatttgtcgt caacagccgt gtcgacgtga aggtggggct
    10741 ggatggcgtt gagtttctcg gagccagcgc ctcagaatgg attaatggcg ggatacgtat
    10801 tctgccgggc gataaaggcg agatgaaagc cagctatcca ctgtatgcca atctggaaaa
    10861 agcgctggag aacagcctta gcgatttacc caccacaacc gtgagtttga gtgcagagac
    10921 gctgccggat gtgcaggcag gatcggtagt gctgtaccgt aaatttgaag ttggtgaagt
    10981 tattaccgtg cgtccgcgag ctaacgcgtt tgatatcgat ctgcatatta agccggagta
    11041 tcgcaacctt ctgaccagca atagcgtgtt ctgggcagaa ggcggggcga aagttcagct
    11101 gaatggtagt ggcctgaccg tacaggcatc cccgctctcc agagcattaa agggagccat
    11161 tagcttcgat aacctcagcg gtgccagcgc cagtcagcgt aaaggcgaca aacgtattct
    11221 gtatgcttcc gaaacagcgg cccgtgcggt tggcgggcag attacgcttc acgctttcga
    11281 tgccggaaaa ctggcggtcg ggatgccaat tcgctatctc ggtattgata tcgggcaaat
    11341 ccagacgctg gatctgatta ccgcgcgcaa tgaagtgcag gcaaaagcgg tgctctatcc
    11401 ggagtatgtc cagaccttcg cccgcggcgg tacgcgcttc tcggtggtca caccgcaaat
    11461 ttcagccgcg ggcgttgagc atcttgatac catcctccag ccgtatatca acgtcgaacc
    11521 aggtcggggt aatcctcacc gcgactttga gttgcaagaa gccaccatta ctgattcgcg
    11581 ttacctggat ggcttaagca ttattgttga agcgcctgaa gccggttcgt taggtattgg
    11641 tacgcctgtg ctgttccgtg gtctggaagt cggtacggtt accggaatga cgctggggac
    11701 attgtctgat cgcgtgatga ttgcgatgcg catcagtaaa cgctatcaac acctggtgcg
    11761 caacaattcc gtcttctggt tggcatcagg ttacagtctg gactttggtc tgacgggcgg
    11821 cgtagtgaaa accggcacct ttaaccaatt tatccgtggc ggcatcgcct tcgccacgcc
    11881 tccgggtacg ccactggcac cgaaagccca ggaaggcaag cacttcctgt tgcaggaaag
    11941 tgaaccgaaa gagtggcgtg aatggggaac agcgcttccc aaataatgcc cactgctccg
    12001 gcgtgcctgc gccggagcgt ttatgctaaa ctgcgcgcct gtttttttgc cagtggtaca
    12061 tgctcgtggc ccaacacacc gtttatttcc cggacgcctt tctgacacaa atgcgcgaag
    12121 caatgccttc gacgctctca tttgatgatt ttcttgccgc ctgtcagcgc ccgttgcgcc
    12181 gcagtattcg cgttaatacg ctgaaaatct ccgttgctga tttcctgcaa ttaaccgccc
    12241 cttatggctg gacgcttacg ccaattccgt ggtgtgaaga aggtttctgg attgaacgcg
    12301 acaatgaaga tgcattgccg ttgggtagta ccgccgagca tttaagtggc ctgttttata
    12361 ttcaggaagc cagttcaatg ttgcccgtcg ccgccttgtt tgctgacggt aatgcaccac
    12421 agcgggtgat ggatgtcgct gccgcgcccg gctccaaaac gacgcaaatt gccgcgcgga
    12481 tgaataacga aggggcgatc cttgccaatg agttttccgc cagtcgggta aaagtgttac
    12541 atgccaatat cagccgctgt ggcatcagta atgttgcgct cacacatttt gatggccgcg
    12601 tgtttggtgc ggcattgcca gaaatgttcg atgccatttt gctggacgct ccctgctccg
    12661 gcgaaggcgt ggtgcgtaaa gatcccgatg cgctaaaaaa ctggtcacca gaaagcaatc
    12721 aggaaatcgc agcgacccaa cgggaactga tcgacagcgc ctttcatgca ttacgccctg
    12781 gcggtacgct ggtttactcg acctgtacct taaacaggga agaaaacgaa gccgtttgcc
    12841 tgtggctgaa agagacttac cccgacgcag tagagttttt accgcttggc gatctcttcc
    12901 ctggtgcaaa taaggcgctg accgaagaag gctttttgca tgttttccca caaatttacg
    12961 actgcgaagg cttcttcgtt gctcgtctgc gtaaaactca ggcgatcccc gtcttacccg
    13021 ccccaaaata caaagtgggc aatttcccgt ttagcccggt gaaagatcgc gaagccagtc
    13081 aaattcgtca ggcggctgca agtgttggct taaactggga tggaaacctg cgactctggc
    13141 aacgcgacaa agaactgtgg ttgttcccgg taggcattga agccctgatc ggtaaagtcc
    13201 gattttctcg gttggggatt aaacttgccg aaacgcataa caaaggttat cgctggcagc
    13261 atgaagcggt tattgccctt gcctcccccg acaatgtgaa cgcttttgaa ctgacaccgc
    13321 aggaagcgga agagtggtat cgcgggcgcg atgtttaccc gcaagccgcg ccagtagcgg
    13381 atgatgtatt ggttactttc cagcatcagc cgattggttt agccaaacga attggttcgc
    13441 gactgaaaaa cagctacccg cgtgaactgg tgcgagacgg gaaacttttt accggtaacg
    13501 cctgacagcg cacaaaaaaa gcgcactttt tgactggcac attcggctgc ctcaactagg
    13561 ctgaaaaatg gtgcgatcgg actggtcgta ccacaatcgg cagctaaatg gagagcacga
    13621 agatgaaaac cagtgtgcgc ataggcgctt ttgaaatcga cgacggcgaa ttacacggcg
    13681 aatcgccggg tgatcgaacg ttaaccattc cttgtaaatc agaccccgat ttatgtatgc
    13741 aactggatgc ctgggatgct gaaaccagta tccctgccct gctaaatggc gaacactctg
    13801 tcctttaccg tacccgttac gatcaacaat ctgatgcctg gattatgcgt cttgcctgat
    13861 ccaaaaagaa cccgtcggca tggcgggtta tttgtcctgg ttattccccc gttgtaaaat
    13921 ctcacctaaa cttaacggta cggcaccaca cttcggggat gaaatgttcg cgctggtact
    13981 ttttgtttgc tacctggatg gcggttgtga agatattgtt gtggatgtct acaacacgga
    14041 acagcagtgt ctttattcta tgagcgatca acggatccgc catggcggtt gttttccgat
    14101 tgaggatttt atagatggtt tctggcgacc tgcacaggaa tacggtgatt tttaattatt
    14161 gcaattgcac aacagtcagt tcgcccccaa agacagcacc ggtatcaata taatgcaggt
    14221 tgccaatatc cacgcgatgg cgcaacggtg tatgaccaaa ccagaaatga tcagcacctg
    14281 taattccctg ccctttttgg cgttcaccta atcgcgagcg gctccacaag acctgatgca
    14341 aatcaacgtc cttttgccat tcataaacat catccggata atcggcatgg gcaataacat
    14401 gtttgccggt gcgactgtgt acttcaagaa taaagggcaa atactgacat ttttccagcg
    14461 ccgttttcgc ttgtttctgt tgataatctg ccagcgcaat aaaccagtcg ccgccattca
    14521 tcaaccataa agacatctgc cgggatgcca gcgcatccat cgccatctgt tcatgattgc
    14581 ctcttaccgc acgaacccaa tgttgttcca gtaactgcag gcaacgtaaa ctttgcggcc
    14641 cacgatcgat aacgtctccc actgagataa gtaaatctcg ccacggatca aaacgacaat
    14701 gccataattt gcggcgcaac tgctcaagac aaccgtgtat atcgcctgaa agccagatat
    14761 gtcgccattg atgacccgca attctctgat aaacgggcgc aggctgtttc atcaatattt
    14821 tcctcccgcg ctaaagatca cataatctta acaagaatgt taaaaaacgc tggactcaga
    14881 cagtagagtg tgtgttatgg ttgactataa agtcagcgaa gggaatgctt ctggctttta
    14941 acagataaaa agagaccgaa cacgattcct gtattcggtc cagggaaatg gctcttggga
    15001 gagagccgtg cgctaaaagt tggcattaat gcaggcttag ttgccttgcc ctttaagaat
    15061 agatgacgac gccaggtttt ccagtttgcg tgcaaaatgg tcaataaaaa gcgcggtggt
    15121 catcagctta aatgttaaaa accgcccgtt ctggtgaaag aactgaggcg gtttttttat
    15181 tggaaatcaa aaggctattt taggtaatta acagagtttt tcagctcgtt ctataaacgg
    15241 tgccagactc attttttcgc cgggattgtt aggatcatca atctgaatca ccgaaatggg
    15301 ttgggcttta gtcttcccac tggcaacttc cttttgtgcg atatcgttta aaggatactg
    15361 cacgagggta cttgggttaa tgacatacaa agcattacct ggtcggcaag tcagcatcac
    15421 ctcttcgcga ttaaacgccc atttgtcttt acccacttca aaacggctga cggtaatcac
    15481 ctgcggtgca gccagcgccg ctgcagaact ggtgagtaac agaaacgcca gaatactttt
    15541 tttcatcatt ttcgtaatcc atcaaaaagg ttcgagagtc gcaagcaggc tgatgatcac
    15601 cagcactacc gcacctatcg cccattcgag tttagtcatc cacacaaacc agggtgccgc
    15661 acgatcttca tcctgcctca tgcgcggtac aagaacataa cgattagcca gcgcgatgac
    15721 caccataatc atcaccagga tggctttgag caataagagt tggccccagt aagtcgtaag
    15781 cgtgggggga aatccggtaa tcaacaatgc attaagcacg ccgcttgcca gtacgccgat
    15841 caccgcaaaa tgcccgcacc aggaaaaacg catcagcgcc tgaatagcct ggtatcgcca
    15901 acggcctttg atgagttgca tacaccagag caccggcagt aatcccccaa accacgccgc
    15961 cgcacaaatc aggtgaatcg cgtgattagt ctgatggatt ttcgccgtta ccccttcatt
    16021 cagcgtcgca tgcccgactc ccgccagcag aaaaaattgc gcggtagtga gcataaacag
    16081 caaaagtggc atattccgcg gttgcataag ggcgacgatc aacgttacga gggcgagaac
    16141 aatttgccat aaccagacgc caccaaactg cgtttgcaaa acagcctgcc aaatgtttgg
    16201 cgaaaataca tctgaccatc ccgttcccat caacccgccc tgaacggcga gcattgcagt
    16261 ggcactgatc aaactccaga cggcagcgtg ctgttgtaaa cgcagaaaac gcttcgtcag
    16321 caagcgacga atcgttaagg gggccagcca ggcaccgtac attgcgaagc caaaaaccag
    16381 catcagcgag gtgaaatgga taaatcgcag cgcgatccag gtaaacgcca gcatgattta
    16441 tttcacgcta aaggtgtagt gtcctttcgt tttatgcccg tccaccgaaa caacatgcca
    16501 gttaacggtg taggttccgg gtttcagcga atcggccagt ggaacaatca gttgcttttg
    16561 gtcctgctca ttccgcttcg ccggtaatgt tttaatattt tcgttttttg gccccgtgat
    16621 ttttgcacca ctgaatcctg tttcaacgcc ttccgagaag tttaaagtga ttgcctgcgg
    16681 agctgctgtc acttgtgcat ttgctgcagg atactgatgc attaaatgcg catgtgccca
    16741 gacggaaggt gtcaccaacg aagtggtcag gattgccagc gcgtagcgaa gggagcgtgc
    16801 agttgaagcc atattatcta ttcctttttg taataacttt tttacagagc ataaccttgt
    16861 ctaatgtctg agtcgaggat catcaattcc ggcttgccat ccaggctcac tcttagtaac
    16921 ttttgcccgc gaatgatgag gagattaaga atgctgaaga atctggctaa actggatcaa
    16981 acagaaatgg ataaagtgaa tgtcgatttg gcggcggcag gggttgcatt taaagaacgc
    17041 tacaatatgc cggtgatcgc tgaagcggtt gaacgtgaac agcctgaaca tttgcgcagc
    17101 tggtttcgcg agcggcttat cgcccaccgt ttggcttcag tcaatctgtc acgtttacct
    17161 tacgagccca aacttaaata aaacttatac atagttacac tttcttacat aacgcctgct
    17221 aaattatgag tattttctaa accgcaccca taatttgcag tcattttgaa aaggaagtca
    17281 ttatgtcgtt ctggaaagtt gcagcagcgc aatatgagcc tcgtaaaacc tcactcaccg
    17341 aacaggtagc tcatcatctg gagtttgtga gggccgccgc caggcaacaa tgtcagctgt
    17401 tagtttttcc atcgctttct ttactggggt gtgattattc gcgacgtgcc cttcctgccc
    17461 cacccgatct ctcgctatta gacccgcttt gttatgctgc aacgacctgg cgaatgacta
    17521 tcattgccgg tcttcccgtt gaatataacg atcgctttat tcgtggaatt gcggtgttcg
    17581 caccgtggcg aaaaacgcca gggatctacc atcagagtca tggtgcatgt ctgggccgtc
    17641 gttccagaac catcacggtg gtcgatgaac aaccggaagg tatggatatg gacccgacct
    17701 gttcactgtt tacgacaggg caatgtctgg gagaacccga cctgctggct tcggcccgtc
    17761 gcttacaatt tttttcacat cagtactcga ttgctgtgct gatggcaaat gcccgtggta
    17821 acagtgcact atgggatgaa catggtcgtc tcatcgttcg cgccgatcgt ggttcattat
    17881 tgttagtcgg tcagcgttca tcacagggtt ggcaaggcga tatcattcca ttacgctagg
    17941 ctttttcggc ctggagcatg ccatgttgcg cattatcgat acagaaacct gcggtttgca
    18001 gggagggatc gttgagattg cctctgttga tgtcattgac ggaaaaatcg tcaaccccat
    18061 gagccacctg gtgcgccccg atcgtcctat tagtccacaa gcgatggcga ttcatcgcat
    18121 caccgaagcc atggtcgccg ataaaccgtg gattgaagat gtgatcccgc actattacgg
    18181 tagtgaatgg tatgtcgcgc acaacgccag ctttgaccgc cgcgtactgc ctgagatgcc
    18241 cggtgagtgg atttgcacta tgaaactggc ccgtcgtttg tggccaggga tcaagtatag
    18301 caatatggcg ttatataaaa cacggaagct caatgtacag acgccgccgg gcctgcatca
    18361 tcaccgcgcg ttgtatgact gttatatcac cgctgcgttg cttatcgata ttatgaacac
    18421 ctccggctgg acggcagaac agatggccga tatcaccgga cgtccgtcgt tgatgacgac
    18481 cttcaccttt ggcaaatacc gtggcaaagc ggtttccgac gttgccgaac gcgatccggg
    18541 ctatctgcgc tggttgttta ataacctgga cagcatgagc ccggagctgc gtttaacact
    18601 aaaacattat ctggaaaata cttaatcctc aggcgtagcg ggtaatgttc cctgcgccag
    18661 cgcgaccaga aaagcatatt ccatcgctac gccttcgtac gatttaaagc ggccagattt
    18721 accgccatgg cctgagtcca tgtcggtaca gagcaataaa agatggttat cggttttcag
    18781 ctcgcgcaat ttagccaccc attttgccgg ttcccaatat tgcacctgag aatcgtgtaa
    18841 accggtcgtt accagtaaat gcggataagc ctgtgcggtg acgttgtcat acgggctgta
    18901 gcttttcatg tactcgtaat attgcggatc ctgcggattc ccccactctt caaactcacc
    18961 agtggtaaga ggaattgatt catcaagcat cgttgttaca acatcaacaa acggtacctg
    19021 ggcgataacg ccgtggaata attccgggcg ttgattaatc gcaacgccca tcaacatgcc
    19081 ccccgcactc ccgcccatcg cataacagag cgaaggtgat ccatagccca gttttaacaa
    19141 tgcatcgcag gcatcaagat aatcattaaa cgtatttttc ttcttcagaa acttaccgtc
    19201 ttcgtaccat tgttgcccca gctcgccacc accacgaaca tggacaatgg cgtagacaaa
    19261 tccacgatcc aacaaactca agcggctaaa actgaaatcg gcatcaatac ttgcgccgta
    19321 agaaccgtag ccatacacca gcagcgggtt gtgtcctttg cgaaaatgtt tgcgatgata
    19381 gaccagcgaa accggaactt cgacgccatc acgggcgact atccacaggt gttcactgcg
    19441 gtaattcgcc gcatcaaaac caggaacttc cgtttgtttt aatacacgac gctcaccggt
    19501 atccatatcc agttcaaaca aagtatctgg tgtggtcatg gaagaataac cataacgcaa
    19561 tcgcgcggtt tcaggttctg gattgtaggc aatccaggtc acataggccg gatcatcaaa
    19621 ggcaatgcca atgacttccc gggtcttgcg gttaatttgc cgcaaactgg ttaacccgcg
    19681 ctgacgctct tcaaccacca gccagtcggt aaacagcgta aacccttcca gcataatgtt
    19741 atcacgtggc ggaattaact cttcccactg ttgctcatca cgcatacggg tacggtataa
    19801 gccaaagttt ttgccgtggc ggttggaacg cagataaaaa cgatgctggt agtgatcaag
    19861 gttgtattcg tgatctttgc ggcgcggcag aaaaacaaac ggctcggcat cggccatttc
    19921 cgcgtccagc aggcgaactt cactggtggt ggcgctggcc agatgaatga ctacatagtg
    19981 cttcgaggtc gttttatgca ggctgacgta ataggtatcg tctttttctt cgtagatcag
    20041 tttatcctgc gatgctggcg taccgatggc gtgacgccag acctgataag gcagcagcgt
    20101 caccggatgc ttgcgaacat agtagaaagt ccaggagtca ttcgcccaga caaagctggg
    20161 ttcaacgtta tccagcagtt ccggatacca gttacctgtt tccagattac gaaaacgaat
    20221 gccgtactgg cgtcgggaaa gaaaatcttc tgccagtgcc ataatggtgt tatctggcgt
    20281 aatcgccatt ccgcccatcg aataaaactc actatgagcc gcgcgcttgt tggcatcgag
    20341 caatgtttcc cactcgtccc actcttcact gaacgccgat tgacgctggt agatagcata
    20401 ttcacagcct ggttcataaa tatgccgata gcggtagcca tttttgatgt agggcgcaga
    20461 aacttctcgt tgcggaatgc ggtcgatgat ttcttttaaa atgcgatcct gcaaggcttg
    20521 ttgcgaggcc atcacccgat gaccgtaact attttcttgt tgcagatagt ccaggacttc
    20581 cggctgagaa cgcgtatcgt cccgcagcca gtagtaatta tcgatgcgcg tatcgccatg
    20641 aagcgtcatg gcgtggggaa tgcgggcggc ttttggtagc atgttattgt tctttctggt
    20701 tgaaacatct tataagggtg gcaaaactca ccggggatgc aagcgaaaca gggtagtcat
    20761 tgcttagatg atgacaggta atggcgcgga tatcgactgt tatgcagaca gagaaaatca
    20821 gcctgttcaa atggctgtgc ggttctggat aacccgaaat agtcaacttc aggctatcca
    20881 gagagcggaa ttactccgcc aaagtacgtt tttgctgttc gagatcgcgt tcaatgcctt
    20941 cacgaacgtc ctgggggatt ttcagcgcat cacccagtgc attcaggtaa ctgcgttcca
    21001 taaaatggtc aatatcaata gccgcgcagc tcaggaaata gatttccagc gcctcttctt
    21061 cattgcgaac cccggtagcc agacgttgtg gatccagcgg ttgttcgatt gcctgctcaa
    21121 tgagtacacg cccctgctct tccacgccgg cttcacgcaa ttgctggtcg attgccgcac
    21181 gttctctggc atcaatatga ccatcacttt tagcggcaaa gaccagcgca aggatcaaac
    21241 gttccgtacg ctcatccagc ggcgtacttt gcgcgccaaa ctgcggttcg tcctgatgcg
    21301 ccgcgcgaat tttatctttg tatttattcc acagcaccgt acccgctacc gctccgccgc
    21361 caaccagtaa cgcgttggtg ccatatttcg taagaagttt acgtgctgat ttatttgcga
    21421 ccagcagccc agccagtccg cctaatgcgc ctggcactaa aagtttgccc aatccctgat
    21481 ccgcagacga ggagacagaa gaactgcttt gcccaagcag ggattgcagt tgatttaacc
    21541 agttagccat atttgctcct caatagccat ttttagtgcc tgtagcatag cggatgagga
    21601 tgtcagaaaa tgtatatcga gacaaaagat gcgcaaataa gcgagtcggt aggccgttat
    21661 tcaaagaaat tcgcgccagg taaggtgttt actgtatatc aggtgataag ggtattttag
    21721 gtgaaagtag tttgacgttt tgagtggcac tgtttgatgc tgattgcccg atgcgacgct
    21781 gttgcgtctt ctcaggccta cgattgtggt gtgttgtggg cggacaaggc actcgcgccg
    21841 catccgccga cggtcaatcg aattatcaga agccattaac gccgctgata ttccgccatt
    21901 cccgctttgc agtccacgct gacctggtaa tgaatatcgg cacttttacc acgcacggtt
    21961 agcggtactg accatttatc atctttcccc tgaatgtcct gcaaactgac ccatgccacg
    22021 gggtcggcct gaccgacaat tttttgatca tcagcccagc gcgccacgcg attttgttgg
    22081 taatcacgtt ttacgctcgc ggcaattccg gcagcatcca gaccttcaca ctttgggaaa
    22141 gtgaccgact tgctggtttc attattggca gcgaaaactg atgcgcaggc agaaaccaac
    22201 aacagcccta aaaacgcccc tctttttttc atgtttttct ccatagcaca atgattcagg
    22261 agaaagcatg gtacaaattg tcaggagcgc aagttgcttc aggccgcgtg tgaggcatct
    22321 tcctcttcgg attcagcacc gacgacctgt ggggacggta atttgccggt tttcagaatg
    22381 gtgctcagca catctttttg ttctgccagc catagcgaaa gggcttcacg ttgctcgtct
    22441 tccatttgca ctggagaatt tgtcagccag gtgtcaagca gatccgccgt atcaagcatt
    22501 ttgtcataag catcggcttc ctttttgctg gtaaacgaca ttttctcttc gccctcacga
    22561 atgactacgt atttaacttc aaccgccatt tgcagcctct cataataact gtgattttat
    22621 acagtatatt tcttctaggt tgggaaatca acatcaacaa taaagacacg cgcaaacgtt
    22681 ttcgtttata ctgcgcgcgg aattaatcag gggatattcg ttatgacgtt attaggcact
    22741 gcgctgcgtc cggcagcaac tcgcgtgatg ttattaggct ccggtgaact gggtaaagaa
    22801 gtggcaatcg agtgtcagcg tctcggcgta gaggtgattg ccgtcgatcg ctatgccgac
    22861 gcgccagcta tgcatgtcgc gcatcgctcc catgtcatta atatgcttga tggtgatgca
    22921 ttacgccgtg tggttgaact ggaaaaacca cattatatcg tgccggagat cgaagctatt
    22981 gccaccgata tgctgatcca acttgaagag gaaggactga atgttgtccc ctgcgcgcgc
    23041 gcaacgaaat taacgatgaa tcgcgagggt atccgtcgcc tggcggcaga agatctgcag
    23101 ctgcccactt ccacttatcg ttttgccgat aacgaaaacc ttttccgcga ggcggttgct
    23161 gacatcggct atccctgcat tgttaaaccg gtgatgagtt cctccggcaa ggggcagacg
    23221 tttattcgtt ctgcagagca acttgctcat gcatgggagt acgctcagca aggcggtcgc
    23281 gccggagcgg gccgcgtaat tgttgaaggc gtcgttaagt ttgatttcga aattaccctg
    23341 ctaaccgtca gcgcggtgga tggcgtccat ttctgtgcac cggtaggtca tcgccaggaa
    23401 gatggcgact atcgtgaatc ctggcaacca caacaaatga gcccgcttgc ccttgaacgt
    23461 gcgcaggaga ttgcccgtaa agtggtgctg gcactgggcg gttatggtct gtttggtgtc
    23521 gagctgtttg tctgtggtga tgaggtgatt ttcagtgagg tctcccctcg cccacatgat
    23581 accgggatgg tgacgttaat ttctcaggat ctctcggagt ttgccctgca tgtgcgagcc
    23641 tttctcggac ttccggttgg cgggatccgt cagtatggtc ctgcagcttc tgccgttatt
    23701 ctgccacaac tgaccagtca gaatgtcacg tttgataatg tgcagaatgc cgtaggcgca
    23761 gatttacaga ttcgtttatt tggtaagccg gaaattgatg gcagccgtcg tctgggggta
    23821 gcactggcta ctgcagagag tgttgttgac gccattgaac gcgcgaagca cgccgccgga
    23881 caggtaaaag tacagggtta aacccggcaa aaaaacgcta caaaaatgcc cgatcctcga
    23941 tcgggcattt tgacttttac agcttagcgc cttctacagc ttcacgcgcc agcttagtaa
    24001 tgcggtcgta atcgcccgct tccagcgcat ctgccggaac cagccaggaa ccaccgatgc
    24061 acagcacgct tttcagcgcc aggtagtcac ggtagttagc cggagaaata ccacctgtcg
    24121 ggcagaaacg gacctgggag aacggacccg cgatcgcctg cagggctttc acaccgccgt
    24181 tagcttcagc cgggaagaat ttgaactctt tcaaaccgta gtccataccc agcatcagtt
    24241 cggaaacagt gctgatcccc ggaatcagag gaatagtccc ttcggtagca gctttcagca
    24301 gcggctcggt cagacccggg ctaattgcaa actgtgcacc cgcttcagtg acttctgcca
    24361 gctgctgtgg attcagcacc gtaccggcac ccacaatcgc ttcaggcact tctttggcga
    24421 tagcacggat agcgtcaact gcgcactcgg tacgcagagt cacttccaga acgcgcaccc
    24481 caccagcaac caacgctttt gccatcggca ccgcgtgttc cagttttttt accacgataa
    24541 ccggtacaac cgggccggtg gtcaggattg attctgcact tgttttccag tttttcatca
    24601 gagttttctc tcgcctgatt acaaatttgt cgtcttaaaa agtgatacag gttgcgccct
    24661 gttcggcacc ggacagtttt tcacgcaagg cgctgaataa ttcacgtcct gttcccacgc
    24721 gtgacgcgct caggtcagga atgtgcggtt cgcgagcagc cagttccgct tcgtctacca
    24781 gcagcgtcag ttcgcctgtc tgtccattca cacgaatgat gtccccgtcg cgcacttttg
    24841 ccagcagccc gccatcgtag gcctctggtg ttacgtggat agctgacggc actttacctg
    24901 aagcgccgga gagtcgtcca tcagtaacta acgcaatttt gaaacaccgg tccaataata
    24961 caccaagtgg cggcatgagt ttatgtaatt ctggcattcc gttcgctttt ggcccctgat
    25021 gacggacaac aacgacacaa tcgcggtcca gcaaacccgc ttcaaaggcc ggcataacgt
    25081 catgctggct ttcaaaaaca accgcaggcg cttcaatcac ctggttctca accggcacgg
    25141 cagaggtttt cataaccgca cggcccaggt taccgcttaa cacttttgtc ccaccatgat
    25201 gagagaaagg ttgttcgaag gaagcgatca cattgctgtc gagtgatttt tccgcccctt
    25261 cccgccagtc cagttcacca ttattcagcc atggttcaag ggtataacga gacagaccaa
    25321 agccagccac cgtattgaca tcttcatgca gcaggcctgc tttgagcagt tcacgcacca
    25381 gaaccggtac gccacctgcc gcctggaagt ggttaatatc agccggaccg ttcgggtaga
    25441 gacgtgccat cagcggtaca acatcagaaa ggtcagagaa gtcatcccag ttaatctgaa
    25501 taccggccgc gcgtgccatc gccaccaggt gcatggtgtg gttagtggaa ccaccggtcg
    25561 ccagcagtgc aacgataccg ttcaccacca ctttctcatc tatcatctta ccgatcggca
    25621 tccattcatt accattaccg gtcatgcgtg taacctggcg cgcagcggct gcggtcaaag
    25681 catcgcgcag cggagaatcc ggatgaacaa aagaagagcc tggcaactgc atccccataa
    25741 actccaccac catctggttg gtgttggcag taccgtagaa agtacatgtt cccggcgcat
    25801 gataagacgc ggcttctgac tccagtaatg ccatgcggtc cactttacct tcggcataaa
    25861 gctggcgaat acgcactttt tctttatttg gcaaaccgct tgccatcggt ccagacggca
    25921 caaacaccgc aggcaaatgc ccaaacgaca gggctgccat cgtcagaccc gggacaatct
    25981 tgtcgcacac accgaggaac agcgcaccat caaacatgtt atgggacagc cccaccgccg
    26041 cagacatcgc aatcacttcg cggcttaaca gcgacaattc cattccatcc tgcccctggg
    26101 tgacaccatc acacatcgcc ggaacaccgc ccgcaacctg accaaccgca ttcgcttcat
    26161 gcagagcttt acgaatgatt tccggatagt gttcataagg ctggtgcgcg gagagcatgt
    26221 cgttatagga ggtgatgatg gcgatattgt tacgcaacat gcttttcaaa gaggctttgt
    26281 cttctggctg gcaagcagcg aaaccgtgtg ccaggttacc gcatgccaac tgcgaacgat
    26341 gaacggtcga agttttcgct tgttctatcc gggcgagata agcagagcga gtctcgcgcg
    26401 aacgttcaat gattcgattt gttacgcgta acaattgtgg gttcataaag gctcctgaag
    26461 ttgagttgtc agagcaggat gattcacaac gcgtttcata catggaaatt atgattgaaa
    26521 cgcctgtaac cggagctcat agggcaaaaa cgtttcagtc agtgtaataa aaaaagcctc
    26581 gtgggtgaat ccgcacgagg cctgaaagtg taaaaattgt tctacaatct gtgcaagatc
    26641 atgttaccgg taaaataacc ataaaggatg agcgcagata ttactcaaac tcattccagg
    26701 aacgaccatc acgggtgatc atcgccactg aggcaacagg tccccaggtt ccggcctgat
    26761 acggtttcgg cgcatcattg tccatcgccc acgcctcagt aatggagtct acccatttcc
    26821 aggcttcttc cacttcatca cgacgtacaa acagtgcctg aataccacgc atggtttcca
    26881 gcagcagacg ttcataggca tctgccagat gcgtttgatt aaaggtttct gaatagctca
    26941 gatccagctt ggtgatttgc aggttatgtt tgtggtcaag gccaggaact ttattcagta
    27001 cctggatatc cacgccttca tcaggttgca gacggatagt cagtttattc tgcggcagat
    27061 cctgccacga ctctttaaac agattcagtt caggtgtttt gaaatagacc acgacttcag
    27121 aacatttggt cggcagacgt ttaccagtac gcaggtagaa tggcacaccg gcccagcgcc
    27181 agttatcaat gtcgacgcgg atcgccacga aggtttctgt attgctgctc ttgttcgcgc
    27241 cctcttcttc cagatagccc ggcacttttt tgccctgagc gaagcccgca gtatattgcc
    27301 cgcgtacggt tttttcgcgc acattggagc ggtcgatgcg gcgcagagac ttcagtactt
    27361 tcactttttc atcgcggatg ctgtctgcgc tcaggtcaga cggcggagac atcgcaatca
    27421 tgcaaagaat ttgcagcagg tggttctgga tcatgtcgcg catctgaccg gctttatcaa
    27481 aatagcccca gcgcccttcg atccccactt cttctgccac ggtaatctca acatgatcaa
    27541 tggtgcgatt gtcccagtta ttcacaaaca gggagttagc aaaacgcagc gccaacaggt
    27601 tcagcaccgt ttctttacca agatagtggt cgatacggta aacctggcac tcctcgaagt
    27661 attcgccaac ctgatcgttg atttcctgcg aggtcgccag cgacgtcccc agcggtttct
    27721 ccatgactac gcgtgccggt ttagcattca gttttgcctc accaagccct ttgcaaattg
    27781 cgccaaaagt gctgggcggc atggcaaaat agttaatggt gatacgattt ttttgatcca
    27841 gcatcgcgcc gagacggctg aatgcagcag tgtcattgac atcgagatta caaaaatcca
    27901 gacgtgcact cagggtgtcc cataaacctt catcaatggt ttctttcatg aaagtttcga
    27961 gcgcctcgcg gacaactttg gtataagccg ctttatccca gtcagcacgc cctacgccga
    28021 taatccgggt gtccgggttg agctgaccgg ctttttccag ttgatacagg gaaggcagca
    28081 atttacgacg cgcaaggtcg cctttcgcgc cgaaaatgac caggtcacag gcctgggctg
    28141 tttgcgttac cgccatgtca ttctccttaa gttaactaac ccggtactta agccagggta
    28201 tacttgtaat tttcttacgg tgcactgtac tgcttttacg agcttgcgaa aactgtaaac
    28261 gcttatccac ccgtgcgatt acggtaaaag cgcgcaaagt gcggcaaaac tgataaaaaa
    28321 atcatcgttt tccattgggt aaaaatctga cactgatcat gttatgaaaa aaaataacaa
    28381 cttttttatc tgcttttgtc attaacacag cacacaggcg taatatctga caaaactgca
    28441 tttcgatttc tttcagtgcg gaaatcgtca ttacccgtga gtctctttac atcatgaata
    28501 tgctggaaaa aatccagtct cagctggaac atttgagcaa atcagagcgc aaagttgccg
    28561 aggtcattct ggcttcgccc gataacgcga tccattcgag tattgctgct ctggcgctgg
    28621 aagccaatgt tagcgaaccg acggtgaatc gtttctgtcg cagcatggac acgcgcggtt
    28681 ttcctgattt taaacttcat ctggcacaaa gtctggcgaa tggcactccc tatgttaatc
    28741 gcaacgtcaa tgaagatgac agcgttgaat catacacggg gaaaatattt gagtccgcaa
    28801 tggcaacgct cgatcatgtc cgtcattcat tggataaatc tgccatcaac cgcgccgtcg
    28861 acttgctcac tcaggcaaaa aaaatcgcct ttttcggatt aggctcttct gccgctgttg
    28921 cccacgatgc gatgaataag ttctttcgtt ttaatgttcc ggtggtgtac tccgatgata
    28981 ttgtgctgca acgcatgagt tgtatgaatt gtagcgacgg agacgtggtg gtgctgattt
    29041 ctcacacggg aagaacaaaa aatctggtcg agctggcgca gctggcacgc gaaaacgacg
    29101 ccatggtgat tgccctcacc tctgcgggca ccccgctcgc ccgggaagca acgctggcaa
    29161 ttaccctcga cgtaccggaa gatactgaca tttatatgcc catggtttct cgacttgcgc
    29221 agctgaccgt gatagatgtg ctggcgacag gatttacttt gcgacgcggt gcaaaattca
    29281 gagataactt gaagcgggtc aaggaagcgc tgaaggaatc gcgttttgat aagcagttac
    29341 ttaatttaag tgacgatcgc taaaaacgac tgtcactgtc ctaatcttat acgacatccg
    29401 aatgagatta atttatcgcc atcgcggcgt tatttcattc ggatttcatg ttcaagcaac
    29461 acctggttgt ttcagtcaac ggagtattac atgtccagaa ggcttcgcag aacaaaaatc
    29521 gttaccacgt taggcccagc aacagatcgc gataataacc ttgaaaaagt tatcgcggcg
    29581 ggtgcaaacg ttgtacgtat gaacttttct cacggctcgc ctgaagatca caaaatgcgc
    29641 gcggataaag ttcgtgagat tgccgcaaaa ctggggcgtc atgtggctat tctgggtgac
    29701 ctccaggggc ccaaaattcg tgtatccacc tttaaagaag gcaaagtttt cctcaatatt
    29761 ggggataaat tcctgctcga cgccaacctg ggtaaaggtg aaggcgacaa agaaaaagtc
    29821 ggtatcgact acaaaggcct gcctgctgac gttgtgcctg gtgacatcct gctgctggac
    29881 gatggtcgcg ttcagttaaa agtactggaa gttcagggca tgaaagtgtt caccgaagtg
    29941 accgttggtg gtcccctctc caacaataaa ggtatcaaca aacttggcgg cggtttgtcg
    30001 gctgaagcgc tgaccgaaaa agacaaagca gacattaaga ctgcggcgtt aattggcgta
    30061 gattacctgg ctgtctcctt cccacgctgc ggcgaagatc tgaactatgc ccgtcggctg
    30121 gcacgcgatg caggatgtga tgcgaaaatt gttgccaagg ttgaacgtgc ggaagccgta
    30181 tgcagccagg atgcaatgga tgacatcatc ctcgcctctg acgtggtaat ggttgcacgc
    30241 ggcgaccttg gtgtggaaat tggcgatccg gaactggtcg gcattcagaa agcgttgatc
    30301 cgtcgtgcgc gtcagcttaa ccgcgcagta atcacggcga cccagatgat ggagtcaatg
    30361 attactaacc cgatgccgac gcgtgcagaa gtcatggacg tagcaaacgc cgttctggat
    30421 ggtactgacg ctgtgatgct gtctgcagaa actgctgctg gtcagtatcc ttcagaaact
    30481 gttgcagcca tggcgcgcgt ttgcctgggt gcggaaaaaa tcccgagcat caacgtttct
    30541 aaacaccgtc tggacgtgca gttcgacaat gtggaagaag ctattgccat gtcagcaatg
    30601 tacgcggcta accacctgaa aggcgttacg gcgatcatca ccatgaccga atcgggtcgt
    30661 accgcgctga tgacctcccg tatcagctct ggtctgccaa ttttcgccat gtcacgccat
    30721 gaacgtacgc tgaacctgac tgctctctat cgcggcgtta cgccggtgca cttcgatagc
    30781 gctaatgacg gcgtagcagc tgccagcgaa gcggttaatc tgctgcgcga taaaggttac
    30841 ttgatgtctg gtgacctggt gattgtcacc cagggcgacg tgatgagtac cgtgggttct
    30901 actaatacca cgcgtatttt aacggtagag taagtacgtt gccggatgcg gcgaaaacgc
    30961 ctcatccggc ctacagttca atgatagttc aacagatttc gaatcttctg aagcaaactt
    31021 gaacttatca cacggcggaa gcctctcctc gcgagaggct ttttttattt gatgggataa
    31081 agatctttgc gcttatacgg ttggatttcg cccggtttgc gagttttcag caattttaat
    31141 atccaggtgt attgttctgg tcgcggacca acaaaaatct cgacttcttc attcatccgc
    31201 cgcgcaatcg tatggtcatc cgcctctaac agatcatcca tcggtgggcg cacctgaatc
    31261 gtcagacgat gcgtcttgcc atcataaatc ggaaacagcg gtacaacgcg cgcacgacac
    31321 actttcatca aacgaccaat cgcgggcaac gtcgctttat aggtggcaaa gaaatcaaca
    31381 aattcgctgt gctctgggcc atgatcctga tcgggtaaat aatatcccca gtagccctga
    31441 cgtaccgact ggatgaatgg tttaatacca tcatttctcg catgcagacg accgccaaag
    31501 cgacgacgca ccgtgttcca gacataatca aaaaccgggt tgccctgatt atggaacatc
    31561 gctgccattt tctgcccttg cgaggccatc agcatggccg ggatatcgac ggcccaaccg
    31621 tgtggcacca gaaaaatcac tttctcgtta ttacgccgca tctcttcgat gatctccagc
    31681 ccttgccagt caacgcgcgg ctgaattttc tccggcccgc gtattgccaa ctcagccatc
    31741 attgccatcg cttgcggcgc ggtggcaaac atctcatcaa caatcgcttc gcgttcagct
    31801 tcactacgtt ctggaaagca gagcgacaaa ttgattaacg cacgacggcg tgagcttttt
    31861 cccagtcgtc cggcaaaacg tcccagccgt gccagaatgg gatcacggaa ctttggcggc
    31921 gttaaagcga tacccgccat cgccgctacg cccagccatg ctccccagta gcgcgggtgg
    31981 cgaaaggatt tatcaaactc aggaatgtat tcgctattat tttttttcgt ttccatgctt
    32041 ttccagtttc ggataaggca aaaatcaatc tggtgatagt gtagcggcgc aacttgcccc
    32101 gcaccaaata aaaaaagccg gtactgactg cgtaccggct gcgaatggat gttaattaat
    32161 caaaccgtag ctgcggcaca atctctttgg cctgcgccag gaattcgcga cgatcggaac
    32221 cggtcagccc ttcggtacgc ggcagttttg ccgtcagcgg gtttacggcc tgctggttta
    32281 tccatacttc atagtgcaga tgcggcccgg ttgaacgtcc ggtattaccg gaaagcgcga
    32341 tgcggtcgcc acgtttcacc ttctgtcccg gtttcaccag aatcttgcgc aggtgcatat
    32401 aacgcgtggt gtagctgcga ccatgacgaa tagccacata ataacctgct gcgccactgc
    32461 gtttggcaac caccacttca ccgtcaccca ctgaaagcac cggcgtaccc tgtggcatgg
    32521 cgaaatcaac acctctgtgt ggcgcaacac gaccagtcac cggattagta cgacgcgggt
    32581 taaagttaga cgagatacgg aactgtttcg ccgtcgggaa tcgcaagaat cctttcgcca
    32641 gaccagtacc gttacgatcg tagaatttgc catcttcagc gcggattgcg taataatctt
    32701 taccttctga acgcaaacgt acgcccagca gctggctttg ctcacgttta ccatcaagca
    32761 tttctcgaga cattaacacc gcaaattcat cgcctttttt cagtttgcgg aaatccattt
    32821 gccactgcat ggctttaatc actgcgctca cttcggcgct ggttaaaccg gcgtttctgg
    32881 cgctggcaac aaagctccct ccgacggtac ctttcagcag attgttaacc cactctcctt
    32941 gctgcatttc gctggtcatt ttaaaaccgt tagcggcagt acggtcatag gttcgggttt
    33001 cacgacgaga cacttcccag gtgaggcgct gcagttcgcc gtccgcggtt aatgtccagg
    33061 agagttgttg accgattttc aggttacgca attctttgtc ggcagcagcc agttgggtga
    33121 tatcacccat atcaatacca tactgattga gaatgctact tagcgtatcg ccagtggaaa
    33181 caacatattc atgcacgccc gcttcaccgg cgattttgtc atccagttca tcctggggaa
    33241 tggcttcatc ttcttgtgca gcttgatcaa tcggctcact ggcttcaggt aagagcgaac
    33301 gaatttcgtt ctgttccagc tcaatggttt tgacaattgg cgtggcgtcg cggtgataaa
    33361 catagggccg ccagacagcg acggccagag taagaacggt gagcgacccc aacataacgc
    33421 ggtgtggtcg cggtaaatta ttaaacgcca gggcgacaga gcgggctatc tgttgcacgt
    33481 aatcacttcc tcattaatct cctttcaggc agctcgcata ctggttggct aattgattca
    33541 ggaattctga atagcttgtt ttacccagtt tgatattcgt ccccagggga tccaacgttc
    33601 ccatacgaac ggatgtccct cgtgcgacgc tctcaacgac cgctggcctg aactgtggct
    33661 cagcaaaaac gcaggttgct ttttgctcaa ccaactgtgt tcttatttca tgtaaacgct
    33721 gcgcgccagg ttgaatctca gggttaacgg taaaatgacc aagcggtgtc agtccgaact
    33781 gtttttcgaa gtagccgtaa gcatcgtgaa aaacgaaata acctttcccc ttgagcggcg
    33841 cgagctcgtt accaacctgc gtttcggttg aggctaattg tgcctcaaaa tccttcaggt
    33901 tggcgtcaag tttggctcga ctttgcggca taagttccac taattttcca tggattgcaa
    33961 ccgctgtagc ccgcgctatc tctggggaaa gccaaagatg catgttgaaa tcgccgtgat
    34021 ggtgatcttc gtcacttttt tccgcgtgat cgtgatcatc atcatcgtcg tgaatacttt
    34081 tcatcagcag cggtttcaca tcttctagct gcgcaatcgt tacctgtttc gcttctggta
    34141 atttacttac cggtttttgc atgaaagctt ccatctccgg gccaacccaa acgactaagt
    34201 ccgcgttctg taagcgtttt acatccgatg gacgcagtga ataatcatgt tctgaagcgc
    34261 cgtcaggcag taaaacctgc gtttctgtta ccccatcagc aatggcagaa gcgatgaacc
    34321 caacaggttt aagcgaagcg acaacggcgg catctgcggc ctgtgttgca ccgccccaga
    34381 gagcggcgga taatgctgcg aaaagaagcg tttttttatg taacataatg cgaccaatca
    34441 tcgtaatgaa tatgagaagt gtgatattat aacatttcat gactactgca agactaaaat
    34501 taacatgaca agtctggttt ccctggaaaa tgtctcggtt tcttttggcc aacgccgcgt
    34561 cctctctgat gtgtcgctgg aacttaaacc tggaaaaatt ttgactttac ttgggccaaa
    34621 tggcgcaggt aagtcgacac tggtacgggt agtgctcggg ctggtaacac ccgatgaagg
    34681 ggttatcaag cgcaacggaa aactgcgcat cggctatgta ccgcagaagc tgtatctcga
    34741 caccacgttg ccactgaccg taaaccgttt tttacgctta cgacctggca cacataaaga
    34801 agatattttg cctgcactga aacgtgtcca ggccggacac ctgattaacg caccgatgca
    34861 aaagctctcg ggtggcgaaa cgcagcgtgt actgttagcg cgagcattgt taaatcgacc
    34921 gcaattatta gtgctggatg aacccactca gggcgtggat gtgaatggtc aggtggcgtt
    34981 atatgacctt attggccaac tgcgtcgtga actggattgt ggcgttttaa tggtctctca
    35041 cgatctgcat ctggtaatgg caaaaaccga tgaagtgctt tgcctgaatc accacatttg
    35101 ttgttccggc acaccggaag ttgtttccct gcatccggag tttatttcta tgtttggtcc
    35161 tcgtggtgct gaacaactgg gtatctatcg ccatcatcat aatcatcgtc acgatttaca
    35221 gggacgaatt gttttgcgtc ggggaaatga tcgctcatga ttgaattatt atttcctggt
    35281 tggttagccg ggatcatgct cgcctgtgcc gcgggtccgc tgggttcgtt tgtcgtctgg
    35341 cgtcgtatgt cttatttcgg tgatacgctg gctcatgcct cattacttgg cgtcgcgttt
    35401 ggtttgttgc tggacgtgaa tccattctat gcggtgattg ccgttacgct gctgctggcg
    35461 ggcggtctgg tatggctgga gaagcgtcca caactggcga tcgacacgtt attagggatt
    35521 atggcgcaca gtgccctgtc gctgggcctg gtggtcgtta gtctgatgtc taatattcgt
    35581 gttgatttga tggcttacct gttcggtgat ttactggcag tgacgccaga agatctcatc
    35641 tctattgcga ttggcgtggt catcgtggtg gctattttgt tctggcaatg gcgcaatttg
    35701 ctgtcgatga cgattagccc ggatctggcg tttgttgatg gtgtgaaatt acagcgcgtg
    35761 aaattgttgt tgatgctggt gacggcattg acgattggtg tagcgatgaa atttgtcggc
    35821 gcgttgatta ttacttcgtt gctgattatt cctgctgcta ctgcgcgtcg ctttgcccgc
    35881 acgccggaac agatggctgg tgtcgctgtt ttggtgggga tggtggcagt gactggcggt
    35941 ttaacctttt ccgcggttta cgatacgccg gcgggtccgt cggtggtgct atgtgcggca
    36001 ctgttattta ttctcagtat gatgaaaaag caggccagct aatctatcgc tgaacacatt
    36061 tgtcggatgc ggcgcgagcg ccttatccga cctacggttc gctatctctg gctggcctga
    36121 taagacgcga acagcgtcgc atcaggcaca ctgccaatgt cggatgcggt gcgagcgcct
    36181 tatctgacct acggttcgct atctctcgta ggccggataa gacgcgaata gcgtcgcatc
    36241 aggcacactg ccaatgtcgg atgcgtcgcg agcgccttat ccgagctacg gttcgctatc
    36301 tctggtaggc cggataagac gcgaatagcg tcgcatcagg cacactgcca atttcggatg
    36361 cggtgcgagc gaccaatccg acttacggca tttctggcgg cgttatgcca aagtgattcc
    36421 acgcccgcgt cgtcgccata cgcccacgcg gtgtacgctg caaaaagcct tgctgaatca
    36481 aataaggttc cagcacatcc tcaatggttt cacgttcttc gccaatggct gccgcaaggt
    36541 tatccagacc taccggccca ccaaagaact tatcgattac cgccagcaat aacttgcggt
    36601 ccatataatc gaaaccttca gcatcgacat tcaacatatc caacgcctga gcagcgatat
    36661 ctgccgagat ggtgccatcg tgcttcactt cggcgaaatc acgcactcga cgcagcagac
    36721 ggttggcaat gcgcggcgta ccgcgagcgc gacgagcaac ttccagcgcc ccgtcatcac
    36781 tcatctcaag ccccataaag cgtgcgctgc gactgacgat atattgcaga tccggcacct
    36841 gataaaactc cagacgttgc acaatcccaa aacggtcgcg caacggtgat gtcagcgaac
    36901 ctgcgcgcgt ggttgcacca atcagggtaa acggcggcaa atcaatttta atggagcgtg
    36961 ccgccggacc ttcaccaatc atgatatcca gttggtagtc ttccattgcc gggtatagca
    37021 cttcttcaac aactggcgat aaacggtgga tctcatcaat aaacagcacg tcatgcggtt
    37081 caaggttagt gagcatcgca gccaaatcgc ccgccttttc cagcaccgga ccagaagtcg
    37141 tgcgtaaatt aacgcccatt tcattggcga caatgttggc aagcgtagtt ttacccaacc
    37201 ccggaggacc aaaaatcaac aaatgatcga gggcatcgcc gcgcagtttc gctgctttga
    37261 tgaaaatctc catctgtgaa cgaacctgcg gctgaccaac atactcttcc agtaatttag
    37321 ggcgaatggc gcgatctgct acatcttccg gcaaagtggt accggcagaa atcagacggt
    37381 ctgcttcaat catcctttac ctcataacgc ggcgcgtagg gcttcgcgaa ttaatgtttc
    37441 actgctggcg tcagggcgag cgattttgct caccatgcgg ctggcttctt gtggtttata
    37501 gcccagcgcc accagcgcag caaccgcttc ctgttcagca tcgttggttg ccgggctggc
    37561 aggcgacgtg agcaccagat cggcggctgg cgtaaagaga tcgccatgca gacctttaaa
    37621 tcggtctttc atttcaacaa tcaagcgttc ggcggttttt ttgccaatac ccggcagttt
    37681 caccagcgcc cccacttctt cacgctcaac ggcattaacg aactgctgcg ctgacattcc
    37741 ggagaggatc gccagcgcca acttcgggcc gacgccgttg gttttgatca actctttgaa
    37801 caacgtgcgc tcttgtttat tgttaaaacc gtacagcagc tgcgcgtctt cacgcaccac
    37861 aaagtgggtg aaaacgatcg cttcctgtcc cgcttcaggg agttcataaa aacaggtcat
    37921 cggcatatgc acttcatagc ctacgccgcc cacttcaatt aacaccagcg ggggttgttt
    37981 ttcaatgatg atgcctctga gtctgcctat cacatgacgc tcctgcgtaa tgaatcaaag
    38041 ataatgctgt atgataaaaa aatgctggat agatatccag cgaaggatga agaaaacttg
    38101 cgaggtgtct cgatgatctg aaaaatggca cagtataatt tattctacag gttattttgg
    38161 aagcaaatat tttaatatta catattcagt gaaaaaatgc gtaataaaaa tatacattgc
    38221 gcctcctgaa
//
LOCUS       DADXDL010000040        38197 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.040, whole genome shotgun sequence.
ACCESSION   DADXDL010000040 DADXDL010000000
VERSION     DADXDL010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 38197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38197
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.040"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            153..1550
                     /locus_tag="IRB70_002364"
     CDS             153..1550
                     /locus_tag="IRB70_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000546464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RtcB family protein"
                     /protein_id="HBC0632269.1"
                     /translation="MHHLSRLDKAFLRKGIQLSRANNIVSLSCPSGASVRVLLPDELP
                     LEEKAVTQLLDFAEVKIPDHPGYVRQTCATPDFHPGNGVPVGAVVASTPDLVIPAAIG
                     TDISCGMRLLTTGLTLEQAEANKDVIAQRLTQVLLQNERDVPLSAQAFTALFDDGPAE
                     CMSALPSAGLWTRTNIPRMVQEIDRCIGLNEHNSHSRYAPPALLVTDRPLLRDPCLGT
                     PGSGNHFIELQVVDSVVDRHVAWQQGLKTGDIVVMIHSGSRDVGFYVGRRWMDRARAE
                     WPTGHKHPQSGLYGLAGGLAEEYLQAMGMAARYAWLNRVTIAEMVRVCFADLFHQDDS
                     HLVVDVPHNIILREHEMNIHRKGATPARAGNLALIPGSMGDYSWLAVGCGNPEWLWSC
                     SHGAGRSQRRQAMHSRATEESTLPWQCVTLREERRIEEAPAAYKDIGPVIEAQQEAGL
                     IHPAVRFRPWLTFKA"
     gene            complement(1648..2517)
                     /gene="sucD"
                     /locus_tag="IRB70_002365"
     CDS             complement(1648..2517)
                     /gene="sucD"
                     /locus_tag="IRB70_002365"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate--CoA ligase subunit alpha"
                     /protein_id="HBC0632270.1"
                     /translation="MSILIDKNTKVICQGFTGSQGTFHSEQAIAYGTKMVGGVTPGKG
                     GTTHLGLPVFNTVREAVAATGATASVIYVPAPFCKDSILEAIDAGIKLIITITEGIPT
                     LDMLTVKVKLDEAGVRMIGPNCPGVITPGECKIGIQPGHIHKPGKVGIVSRSGTLTYE
                     AVKQTTDYGFGQSTCVGIGGDPIPGSNFIDILEMFEKDPQTEAIVMIGEIGGSAEEEA
                     AAYIKEHVTKPVVGYIAGVTAPKGKRMGHAGAIIAGGKGTADEKFAALEAAGVKTVRS
                     LADIGEALKTVLK"
     gene            complement(2517..3683)
                     /gene="sucC"
                     /locus_tag="IRB70_002366"
     CDS             complement(2517..3683)
                     /gene="sucC"
                     /locus_tag="IRB70_002366"
                     /EC_number="6.2.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-forming succinate--CoA ligase subunit beta"
                     /protein_id="HBC0632271.1"
                     /translation="MNLHEYQAKQLFARYGLPAPVGYACTTPREAEEAASKIGAGPWV
                     VKCQVHAGGRGKAGGVKVVNSKEDIRAFAENWLGKRLVTYQTDANGQPVNQILVEAAT
                     DIAKELYLGAVVDRSSRRVVFMASTEGGVEIEKVAEETPHLIHKVALDPLTGPMPYQG
                     RELAFKLGLEGKLVQQFTKIFMGLATIFLERDLALIEINPLVITKQGDLICLDGKLGA
                     DGNALFRQPDLREMRDQSQEDPREAQAAQWELNYVALDGNIGCMVNGAGLAMGTMDIV
                     KLHGGEPANFLDVGGGATKERVTEAFKIILSDDKVKAVLVNIFGGIVRCDLIADGIIG
                     AVAEVGVNVPVVVRLEGNNAELGAKKLADSGLNIIAAKGLTDAAQQVVAAVEGK"
     gene            complement(3777..4994)
                     /gene="odhB"
                     /locus_tag="IRB70_002367"
     CDS             complement(3777..4994)
                     /gene="odhB"
                     /locus_tag="IRB70_002367"
                     /EC_number="2.3.1.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase complex
                     dihydrolipoyllysine-residue succinyltransferase"
                     /protein_id="HBC0632272.1"
                     /translation="MSSVDILVPDLPESVADATVATWHKKPGDAVVRDEVLVEIETDK
                     VVLEVPASADGILDAVLEDEGTTVTSRQILGRLREGNSAGKETSAKSEEKASTPAQRQ
                     QASLEEQNNDALSPAIRRLLAEHNLDASAIKGTGVGGRLTREDVEKHLAKAPAKESAP
                     AAAAPAAQPALAARSEKRVPMTRLRKRVAERLLEAKNSTAMLTTFNEVNMKPIMDLRK
                     QYGEAFEKRHGIRLGFMSFYVKAVVEALKRYPEVNASIDGDDVVYHNYFDVSMAVSTP
                     RGLVTPVLRDVDTLGMADIEKKIKELAVKGRDGKLTVEDLTGGNFTITNGGVFGSLMS
                     TPIINPPQSAILGMHAIKDRPMAVNGQVEILPMMYLALSYDHRLIDGRESVGFLVTIK
                     ELLEDPTRLLLDV"
     gene            complement(5009..7810)
                     /gene="sucA"
                     /locus_tag="IRB70_002368"
     CDS             complement(5009..7810)
                     /gene="sucA"
                     /locus_tag="IRB70_002368"
                     /EC_number="1.2.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-oxoglutarate dehydrogenase E1 component"
                     /protein_id="HBC0632273.1"
                     /translation="MQNSALKAWLDSSYLSGANQSWIEQLYEDFLTDPDSVDANWRST
                     FQQLPGTGVKPDQFHSQTREYFRRLAKDASRYSSTISDPDTNVKQVKVLQLINAYRFR
                     GHQHANLDPLGLWQQDKVADLDPSFHDLTEADFQETFNVGSFASGKETMKLGELLEAL
                     KQTYCGPIGAEYMHITSTEEKRWIQQRIESGRATFNSEEKKRFLSELTAAEGLERYLG
                     AKFPGAKRFSLEGGDALIPMLKEMIRHAGNSGTREVVLGMAHRGRLNVLVNVLGKKPQ
                     DLFDEFAGKHKEHLGTGDVKYHMGFSSDFQTDGGLVHLALAFNPSHLEIVSPVVIGSV
                     RARLDRLDEPSSNKVLPITIHGDAAVTGQGVVQETLNMSKARGYEVGGTVRIVINNQV
                     GFTTSNPLDARSTPYCTDIGKMVQAPIFHVNADDPEAVAFVTRLALDFRNTFKRDVFI
                     DLVCYRRHGHNEADEPSATQPLMYQKIKKHPTPRKIYADKLEQEKVATLEDATEMVNL
                     YRDALDAGDCVVAEWRPMNMHSFTWSPYLNHEWDEEYPNKVEMKRLQELAKRISTVPE
                     AIEMQSRVAKIYGDRQAMAAGEKLFDWGGAENLAYATLVDEGIPVRLSGEDSGRGTFF
                     HRHAVIHNQSNGSTYTPLQHIHNGQGAFRVWDSVLSEEAVLAFEYGYATAEPRTLTIW
                     EAQFGDFANGAQVVIDQFISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQL
                     CAEQNMQVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGT
                     FLPAIGEIDELDPKGVKRVVMCSGKVYYDLLEQRRKNNQHDVAIVRIEQLYPFPHKAM
                     QEVLQQFAHVKDFVWCQEEPLNQGAWYCSQHHFREVIPFGASLRYAGRPASASPAVGY
                     MSVHQKQQQDLVNDALNVE"
     gene            complement(8011..8727)
                     /gene="sdhB"
                     /locus_tag="IRB70_002369"
     CDS             complement(8011..8727)
                     /gene="sdhB"
                     /locus_tag="IRB70_002369"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase iron-sulfur subunit
                     SdhB"
                     /protein_id="HBC0632274.1"
                     /translation="MRLEFSIYRYNPDVDDAPRMQDYTLEAEEGRDMMLLDALIQLKE
                     KDPSLSFRRSCREGVCGSDGLNMNGKNGLACITPISALNQPGKKIVIRPLPGLPVIRD
                     LVVDMGQFYAQYEKIKPYLLNNGQNPPAREHLQMPEQREKLDGLYECILCACCSTSCP
                     SFWWNPDKFIGPAGLLAAYRFLIDSRDTETDSRLDGLSDAFSVFRCHSIMNCVSVCPK
                     GLNPTRAIGHIKSMLLQRNA"
     gene            complement(8743..10509)
                     /gene="sdhA"
                     /locus_tag="IRB70_002370"
     CDS             complement(8743..10509)
                     /gene="sdhA"
                     /locus_tag="IRB70_002370"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase flavoprotein subunit"
                     /protein_id="HBC0632275.1"
                     /translation="MKLPVREFDAVVIGAGGAGMRAALQISQSGQTCALLSKVFPTRS
                     HTVSAQGGITVALGNTHEDNWEWHMYDTVKGSDYIGDQDAIEYMCKTGPEAILELEHM
                     GLPFSRLDDGRIYQRPFGGQSKNFGGEQAARTAAAADRTGHALLHTLYQQNLKNHTTI
                     FSEWYALDLVKNQDGAVVGCTALCIETGEVVYFKARATVLATGGAGRIYQSTTNAHIN
                     TGDGVGMAIRAGVPVQDMEMWQFHPTGIAGAGVLVTEGCRGEGGYLLNKHGERFMERY
                     APNAKDLAGRDVVARSIMIEIREGRGCDGPWGPHAKLKLDHLGKEVLESRLPGILELS
                     RTFAHVDPVKEPIPVIPTCHYMMGGIPTKVTGQALTVNEKGEDVVVPGLFAVGEIACV
                     SVHGANRLGGNSLLDLVVFGRAAGLHLQESIAEQGALRDASESDVEASLDRLNRWNNN
                     RNGEDPVAIRKALQECMQHNFSVFREGDAMAKGLEQLKVIRERLKNARLDDTSSEFNT
                     QRVECLELDNLMETAYATAVSANFRTESRGAHSRFDFPDRDDENWLCHSLYLPESESM
                     TRRSVNMEPKLRPAFPPKIRTY"
     gene            complement(10509..10856)
                     /gene="sdhD"
                     /locus_tag="IRB70_002371"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
     CDS             complement(10509..10856)
                     /gene="sdhD"
                     /locus_tag="IRB70_002371"
                     /gene_synonym="cybS"
                     /gene_synonym="dhsD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase membrane anchor subunit"
                     /protein_id="HBC0632276.1"
                     /translation="MVSNASALGRNGVHDFILVRATAIVLTLYIIYMVGFFATSGELT
                     YEVWIGFFASAFTKVFTLLALFSILIHAWIGMWQVLTDYVKPLALRLMLQLVIVVALV
                     VYVIYGFVVVWGV"
     gene            complement(10850..11254)
                     /gene="sdhC"
                     /locus_tag="IRB70_002372"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
     CDS             complement(10850..11254)
                     /gene="sdhC"
                     /locus_tag="IRB70_002372"
                     /gene_synonym="cybA"
                     /gene_synonym="dhsC"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000263334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HBC0632277.1"
                     /translation="MWALFMIRNVKKQRPVNLDLQTIRFPVTAIASILHRVSGVITFV
                     AVGILLWLLGTSLSSPEGFEQASAIMGSFFVKFIMWGILTALAYHVVVGIRHMMMDFG
                     YLEETFEAGKRSAKISFVITVVLSLLAGVLVW"
     gene            11635..11742
                     /locus_tag="IRB70_002373"
     CDS             11635..11742
                     /locus_tag="IRB70_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632278.1"
                     /translation="MRKSYEVGISPKINLCNSVEVLTNSFGTVISGRQV"
     gene            11948..13231
                     /gene="gltA"
                     /locus_tag="IRB70_002374"
     CDS             11948..13231
                     /gene="gltA"
                     /locus_tag="IRB70_002374"
                     /EC_number="2.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (Si)-synthase"
                     /protein_id="HBC0632279.1"
                     /translation="MADTKAKLTLNGDTAVELDVLKGTLGQDVIDIRTLGSKGVFTFD
                     PGFTSTASCESKITFIDGDEGILLHRGFPIDQLATDSNYLEVCYILLNGEKPTQEQYD
                     EFKTTVTRHTMIHEQITRLFHAFRRDSHPMAVMCGITGALAAFYHDSLDVNNPRHREI
                     AAFRLLSKMPTMAAMCYKYSIGQPFVYPRNDLSYAGNFLNMMFSTPCEPYEVNPILER
                     AMDRILILHADHEQNASTSTVRTAGSSGANPFACIAAGIASLWGPAHGGANEAALKML
                     EEISSVKHIPEFVRRAKDKNDSFRLMGFGHRVYKNYDPRATVMRETCHEVLKELGTKD
                     DLLEVAMELENIALNDPYFIEKKLYPNVDFYSGIILKAMGIPSSMFTVIFAMARTVGW
                     IAHWSEMHSDGMKIARPRQLYTGYAQRDFKSDIKK"
     gene            complement(13278..14588)
                     /locus_tag="IRB70_002375"
     CDS             complement(13278..14588)
                     /locus_tag="IRB70_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000126139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBC0632280.1"
                     /translation="MTALSELLAGSWLDNWLMIIPLMFICLFINMPVWLAMFCGILTY
                     FLCYSNVPLMVAIQRLIATTQTPSLLAIPFFILLGTLMSYTGIAARILQIANVLIGRM
                     RGGLGGANILVSTMMGGVSASNLADAAMLSRMMVPEMEQKGYSRGFAAAITASGSLIT
                     PIIPPGIALILYGLVADVSIGSMFMAGILPGLLCSAMLIVTVWLVAIRRGLKPSSEHW
                     PKPKEVSVALVQAWPALFLIVAVIGGIRANIFTPTEAGAVAVLLVMFIGFVIYRELKI
                     SHVFTALSETARSTASVMLIIMASAALGWIFSLERAGITVAEFVTSLTDNKYVFLLII
                     NLLLLVLGMFLEGSAILLILVPLLKPVVAHFGIDPVHFGIIMILNLSLGTLSPPVGTV
                     MLLVCNTVQVSVGQFMREAVPLLVSLILLLLVITYIPAISLLLV"
     gene            complement(14588..15049)
                     /locus_tag="IRB70_002376"
     CDS             complement(14588..15049)
                     /locus_tag="IRB70_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001237778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBC0632281.1"
                     /translation="MRLLGKMIEVAAVLTLFILVIMTIAAVIMRYCFHMPLQWTEEVS
                     GLLMIWVVMFGAVVAERDNTHLSIPFLADALTPRVQRVLTLFVSLISIVLLSVMAWSA
                     WKLAAGTAFKTTQILKISWFWIDIAVTVGAIGIACFTALHLIKKTPRKEGE"
     gene            complement(15109..16077)
                     /locus_tag="IRB70_002377"
     CDS             complement(15109..16077)
                     /locus_tag="IRB70_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000034588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate TRAP transporter
                     substrate-binding protein"
                     /protein_id="HBC0632282.1"
                     /translation="MKKLLTPFLFLFALLSPMLNAAPVTIKIAYESNPGEPADTVVKH
                     WAELVKKKSNGDIVFELYPSSQLGSKQDITEQALMGMNIITISDVGFLTDYDADLGIL
                     FGPYLSEDPQKLFAIYASDWFKQKEQKLREKGVHIVMSNYLYGTRQIIAKKPIRTPED
                     LKGMKIRVPNNVMQIKAIEAMGATPTPMPLGDVYPALTQGMIDGVENPVSVLYGQKLH
                     EQAKYLSMVNYLTNTSLWLGGEAFFSTLTPAQLDIIHQTAYEAGLYSQKITTEQGATM
                     LKTMQEQGVEIIYPDVAPFKEKALKVYQQFPEWTPGLYDTIQQQLK"
     gene            complement(16105..17301)
                     /locus_tag="IRB70_002378"
     CDS             complement(16105..17301)
                     /locus_tag="IRB70_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000399432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBC0632283.1"
                     /translation="MEGYVRQNGRPGIRNTVQVIFMVECASHVAKKIAEGFPCHDVQY
                     FGFSGCYPSDYGYRLVKNLAIHSNVGGVLIISLGCENFDRRRLEQEVRESGRPCHTLV
                     IQENKGTTNTITLGKQLVAEMLEQLADTLRCILNWSDLVVGTICGGSDGTSGITGNPA
                     VGRAFDQLLEKGATCIFEESGELLGCEQHMMSRAASSQARDAIEVAMTKAERYYSLMG
                     LGSFSNGNAEGGLTTQEEKSLGAYTKSGDALIAGVILPTQQAPFPGLWLMDVVPDGEP
                     RFGYPNINDSSEALELIASGCHMVLFTTGRGSVIGSVIAPIIKVCNNPQTWEHLSDDM
                     DVNAGRVISEGATLDDIADDIMQVIEHVANGQYCAAERLEHQEFVLTYKAFDYSKSAV
                     CRADPR"
     gene            complement(17301..17612)
                     /locus_tag="IRB70_002379"
     CDS             complement(17301..17612)
                     /locus_tag="IRB70_002379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002432396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UxaA family hydrolase"
                     /protein_id="HBC0632284.1"
                     /translation="MRKRALKLHAKDNCVVALNDITSGDIVWWDEGEMVACSSVTLGH
                     KLACEALNNGDSILKYGAIIGHATRDIAMGEHVHSHNLASNAIAIFHHDDAGYQPEEK
                     A"
     gene            complement(17627..18382)
                     /locus_tag="IRB70_002380"
     CDS             complement(17627..18382)
                     /locus_tag="IRB70_002380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000991076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBC0632285.1"
                     /translation="MNAFSLHNKTALITGAASGLGLAMAKCMIVSGAKVIIADLNGEL
                     AQATAGTLGSQASWIQMDVGDTAAAQEKVDALISEHGAIDILVNNAGNHCKKPIEEMS
                     VSDFESVLDVHVVGAFALTKALVPHMKQRGQGCVLFTASMTSFLGQPLVTGYSAAKSA
                     YLGMIRGMTTELAVHGIRVNGIAPGWIDTPMLRKAIEGDDERRNKILGRTPMKKFGKP
                     EDIGWAAVYLASDAAAFVSGQVLVVDGGALIGF"
     gene            complement(18394..19407)
                     /locus_tag="IRB70_002381"
     CDS             complement(18394..19407)
                     /locus_tag="IRB70_002381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBC0632286.1"
                     /translation="MKALTIEQGSQARFVDIPEPVCGKGEVLINVERVGLCGSDLNTW
                     RGLNPLVNYPCIPGHEIGGTVLATGDMAGAIKPGDRVVVLPCTECGVCSSCLSGRPNA
                     CKNNQTLGVQRQGGMAQQLTMPAHKVIVCNALSVDELALVEPLAVGLHAARRAQINVG
                     EWVAVIGCGVIGLGAIAAASAMGARVIAIDIDDRKQNIALECGAQRFLNSQQCDVAAE
                     LVLLNDGRGPEVVIEAVGNQQTIEQATGLVAFSGRVVYVGYAKQPVSYQSAQFLMKEL
                     DIRGSRNATVADFRAVLALMESGRYPVSNLVSAHYPLEQADHAFSDWASDPGAYTKIL
                     IDL"
     gene            complement(19420..20106)
                     /locus_tag="IRB70_002382"
     CDS             complement(19420..20106)
                     /locus_tag="IRB70_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000265972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RraA family protein"
                     /protein_id="HBC0632287.1"
                     /translation="MWKSDNELFALMKTRLFTAVVGDILDTLGYMHQFVSPAIKPLDV
                     NTVVAGRAMPVLESDVYETKSTSGKTAIGEKPFGIMFEALDALKENDVYITTGSSLRY
                     ALWGGLMSTRAMHLKAAGAVLDGYARDSAEILELKFPTFCHGTYAQDQGPRGKVIDFG
                     VPIEFHGVRVNPGDIVFGDRDGLLIIPQVVEKEVITQALEKVATESEVRKAISDGMST
                     VQAFETFGVM"
     gene            20370..21083
                     /locus_tag="IRB70_002383"
     CDS             20370..21083
                     /locus_tag="IRB70_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBC0632288.1"
                     /translation="MSESALLTSVTLSSQVKNHILNLIAEQKLTPGMPVPSEIQLIQK
                     LGVSRGIVREAYRSLAALGILETHSGKVPRIKKFDDEVLRVVFGFALATEQVTTEQIL
                     QVRRWLELGVVEAAARNGGEEDFANLRAEMAKIREQFDDVESFITHDIRFHQLLAVAS
                     KNPLFMMLLQALHQQLRQSIQEGLNAQSDQKEYGNHIITLHQKICDAVCARDVETATQ
                     AMKSHFDSPVSALINNSSP"
     gene            21263..22309
                     /locus_tag="IRB70_002384"
     CDS             21263..22309
                     /locus_tag="IRB70_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415243.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBC0632289.1"
                     /translation="MPVLQWGMLCVLSLLLSIGFLALHLPAALLLGPMIAGIIFSMRG
                     VTLQLPRSAFLAAQAILGCMIAQNLTGSILTTLAVNWPIVLAILLVTLLSSAIVGWLL
                     VRYSSLPGNTGAWGSSPGGAAAMVAMAQDYGADIRLVAFMQYLRVLFVAGAAVLVTRM
                     MLGDNAEAVNQQIVWFPPVSINLLLTIMLAVVAGTAGCLLRLPSGTMLIPMLAGAVLQ
                     SGQLITIELPEWLLAIAYMAIGWRIGLGFDKQILLRALRPLPQILLSIFALLAICAGM
                     AWGLTRFMHIDFMTAYLATSPGGLDTVAVIAAGSNADMALIMAMQTLRLFSILLTGPA
                     IARFISTYAPKRSA"
     gene            complement(22306..23097)
                     /gene="nei"
                     /locus_tag="IRB70_002385"
     CDS             complement(22306..23097)
                     /gene="nei"
                     /locus_tag="IRB70_002385"
                     /EC_number="4.2.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease VIII"
                     /protein_id="HBC0632290.1"
                     /translation="MPEGPEIRRAADNLEAAIKGKPLTDVWFAFPQLKSYQSQLIGQH
                     VTHVETRGKALLTHFSNELTLYSHNQLYGVWRVVDTGKEPQTTRVLRVKLQTADKTIL
                     LYSASDIEMLTPEQLTTHPFLQRIGPDVLDPNLTPEVVKERLLSPRFRNRQFAGLLLD
                     QAFLAGLGNYLRVEILWQVGLTGNHKAKDLNAAQLDALAHALLDIPRLSYATRGQVDE
                     NKHHGALFRFKVFHRDSEPCERCGGIIEKTTLSSRPFYWCPGCQH"
     gene            complement(23133..23867)
                     /gene="pxpA"
                     /locus_tag="IRB70_002386"
     CDS             complement(23133..23867)
                     /gene="pxpA"
                     /locus_tag="IRB70_002386"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpA"
                     /protein_id="HBC0632291.1"
                     /translation="MKIDLNADLGEGCVSDAELLTLVSSANIACGFHAGDAQIMHACV
                     REAIKNGVAIGAHPSFPDRENFGRSAMQLPPETVYAQTLYQIGALAAIARAQGGVMRH
                     VKPHGMLYNQAAKEAQLADAIARAVYACDPALILVGLAGSELIRAGKQYGLTTREEVF
                     ADRGYQADGSLVPRSQPGALIENEEQALAQTLEMVQHGRVKSITGEWATVTAQTVCLH
                     GDGEHALAFARRLRATFAEKGIVVAA"
     gene            complement(23857..24789)
                     /gene="pxpC"
                     /locus_tag="IRB70_002387"
     CDS             complement(23857..24789)
                     /gene="pxpC"
                     /locus_tag="IRB70_002387"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpC"
                     /protein_id="HBC0632292.1"
                     /translation="MLKIIRAGMYTTVQDGGRHGFRQSGISHCGALDMPALRIANLLV
                     GNDANAPALEITLGQLTVEFETDGWFALTGAGCEARLDDNAVWTGWRLPMKAGQRLTL
                     KRPQHGMRSYLAVAGGIDVPPVMGSCSTDLKVGIGGLEGRLLKDGDRLPIGKAKRDFM
                     EALGVKQLLWGNRIRALPGPEYHEFDRASQDAFWRSPWQLSSQSNRMGYRLQGQILKR
                     TTDRELLSHGLLPGVVQVPHNGQPIVLMNDAQTTGGYPRIACIIEADMYHLAQIPLGQ
                     PIHFVQCSLEEALKARQDQQRYFEQLAWRLHNEN"
     gene            complement(24783..25439)
                     /gene="pxpB"
                     /locus_tag="IRB70_002388"
     CDS             complement(24783..25439)
                     /gene="pxpB"
                     /locus_tag="IRB70_002388"
                     /EC_number="3.5.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-oxoprolinase subunit PxpB"
                     /protein_id="HBC0632293.1"
                     /translation="MQRARCYLIGETAVVLELEPPVTLASQKRIWRLAQRLVDMPNVV
                     EVIPGMNNITVILRNPESLALDAIERLQRWWEESEALEPESRFIEIPVVYGGAGGPDL
                     AVVAAHCGLSEKQVVELHSSVEYVVWFLGFQPGFPYLGSLPEQLHTPRRAEPRLLVPA
                     GSVGIGGPQTGVYPLATPGGWQLIGHTSLSLFDPARDEPILLRPGDSVRFVPQKEGVC
                     "
     gene            complement(25462..26205)
                     /gene="ybgI"
                     /locus_tag="IRB70_002389"
     CDS             complement(25462..26205)
                     /gene="ybgI"
                     /locus_tag="IRB70_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000798886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radiation resistance protein YbgI"
                     /protein_id="HBC0632294.1"
                     /translation="MKNTELEQLINEKLNSAAISDYAPNGLQVEGKETVQKIVTGVTA
                     SQALLDEAVRLGADAVIVHHGYFWKGESPVIRGMKRNRLKTLLANDINLYGWHLPLDA
                     HPELGNNAQLAALLGITVMGEIEPLVPWGELTMPVPGLELASWIEARLGRKPLWCGDT
                     GPEVVQRVAWCTGGGQSFIDSAARFGVDAFITGEVSEQTIHSAREQGLHFYAAGHHAT
                     ERGGIRALSEWLNENTDLDVTFIDIPNPA"
     gene            26476..27957
                     /gene="dtpD"
                     /locus_tag="IRB70_002390"
     CDS             26476..27957
                     /gene="dtpD"
                     /locus_tag="IRB70_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide permease DtpD"
                     /protein_id="HBC0632295.1"
                     /translation="MNKHASQPRAIYYVVALQIWEYFSFYGMRALLILYLTNQLKYSD
                     NHAYELFSAYCSLVYVTPILGGFLADKVLGNRMAVMLGALLMAIGHVVLGASEIHPSF
                     LYLSLSIIVCGYGLFKSNVSCLLGELYEPTDPRRDGGFSLMYAAGNVGSIIAPIACGF
                     AQEEYSWAMGFGLAAVGMIAGLVIFLCGNRHFTHTRGVNKKVLRATNFLLPNWGWLLV
                     LLVATPALITVLFWKEWSVYALIVATIIGLGVLAKIYRKAENQKQRKELGLIVTLTFF
                     SMLFWAFAQQGGSSISLYIDRFVNRDMFGYTVPTAMFQSINAFAVMLCGVFLAWVVKE
                     SVAGNRTVRIWGKFALGLGLMSAGFCILTLSARWSAMYGHSSLPLMVLGLAVMGFAEL
                     FIDPVAMSQITRIEIPGVTGVLTGIYMLLSGAIANYLAGVIADQTSQASFDASGAINY
                     SINAYIEVFDQITWGALACVGVVLMIWLYQALKFRNRALALES"
     gene            complement(27999..29417)
                     /gene="phrB"
                     /locus_tag="IRB70_002391"
     CDS             complement(27999..29417)
                     /gene="phrB"
                     /locus_tag="IRB70_002391"
                     /EC_number="4.1.99.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribodipyrimidine photo-lyase"
                     /protein_id="HBC0632296.1"
                     /translation="MTTHLVWFRQDLRQHDNLALAAACRNSSARVLALYIATPRQWAA
                     HNMSPRQAEFINAQLNGLQIALAEKGIPLLFHEVDDFAASVEIVKQVCAENRVTHLFY
                     NYQYEVNERARDVQAERALRNVVCEGFDDGVILPPGAVMTGNHEMYKVFTPFKNAWLK
                     RLREGMPECVAAPKVRSSGSIDPAPSITLNYPRQPFDTAHFPVEEKAAIAQLRQFCQN
                     GAGEYEQQRDFPAVEGTSRLSASLATGGLSPRQCLHRLLAEQPQALDGGAGSIWLNEL
                     IWREFYRHLITYYPSLCKHRPFIVWTDRVQWQSNSAHLKAWQEGKTGYPIVDAAMRQL
                     NSTGWMHNRLRMITASFLVKDLLIDWREGERYFMSQLIDGDLAANNGGWQWAASTGTD
                     AAPYFRIFNPTTQGEKFDREGEFIRQWLPELRDVPGKVVHEPWKWAQKAGVTLDYPQP
                     IVDHKEARLRTLAAYEEARKGV"
     gene            complement(29414..29923)
                     /locus_tag="IRB70_002392"
     CDS             complement(29414..29923)
                     /locus_tag="IRB70_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbgA family protein"
                     /protein_id="HBC0632297.1"
                     /translation="MNQQLFDDSTLIRIFALHELHNLKDRGLTRGALLDYHSRYKLVF
                     LAHSQPEYRKLGPFVADIHQWQNLDDYYNQYRQRVVVLLSHPANRRDHTNVLMHVQGY
                     FRPHIDSTERQQLAALIDSYRGGEQPLLAPLMRIKHYMALYPDAWLSGQRYFELWPRV
                     INLRHSGVL"
     gene            complement(30024..30230)
                     /locus_tag="IRB70_002393"
     CDS             complement(30024..30230)
                     /locus_tag="IRB70_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbfA family protein"
                     /protein_id="HBC0632298.1"
                     /translation="MELYKEYPAWLIFLRRTCAVAAGVLALPFMLFWKDRARFYSYLH
                     RVWSKTSEKPVWMDQAEKATGDFY"
     gene            30543..30632
                     /gene="kdpF"
                     /locus_tag="IRB70_002394"
     CDS             30543..30632
                     /gene="kdpF"
                     /locus_tag="IRB70_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit F"
                     /protein_id="HBC0632299.1"
                     /translation="MSAGVIAGVLLVFLLLGYLVYALINAEAF"
     gene            30632..32305
                     /gene="kdpA"
                     /locus_tag="IRB70_002395"
     CDS             30632..32305
                     /gene="kdpA"
                     /locus_tag="IRB70_002395"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpA"
                     /protein_id="HBC0632300.1"
                     /translation="MAAQGFLLIATFLLVLMVLARPLGSGLARLINDIPLPGTTGVER
                     VLFSALGVSDREMNWKQYLSAILGLNILGLAVLFFMLLGQHYLPLNPQQLPGLSWDLA
                     LNTAVSFVTNTNWQSYSGETTLSYFSQMAGLTVQNFLSAASGIAVIFALIRAFTRQSM
                     STLGNAWVDLLRITLWVLVPVALLIALFFIQQGALQNFQPYQAVNTVEGAKQLLPMGP
                     VASQEAIKMLGTNGGGFFNANSSHPFENPTALTNFVQMLAIFLIPTALCFAFGEVAGD
                     RRQGRMLLWAMSVIFIICTGVVMWAEVQGNPHLLALGADSSINIEGKESRFGVLVSSL
                     FAVVTTAASCGAVIAMHDSFTALGGMVPMWLMQIGEVVFGGVGSGLYGMMLFVLLAVF
                     IAGLMIGRTPEYLGKKIDVREMKLTALAILVTPTLVLMGAALAMMTDAGRSAMLNPGP
                     HGFSEVLYAVSSAANNNGSAFAGLSANSPFWNCLLALCMFVGRFGVIIPVMAIAGSLV
                     SKKSQPASSGTLPTHGPLFVGLLIGTVLLVGALTFIPALALGPVAEYLS"
     gene            32328..34376
                     /gene="kdpB"
                     /locus_tag="IRB70_002396"
     CDS             32328..34376
                     /gene="kdpB"
                     /locus_tag="IRB70_002396"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium-transporting ATPase subunit KdpB"
                     /protein_id="HBC0632301.1"
                     /translation="MSRKQLALFEPTLVVQALKEAVKKLNPQAQWRNPVMFIVWIGSL
                     LTTFICIAMASGAMPGNALFSAAISGWLWVTVLFANFAEALAEGRSKAQANSLKGVKK
                     TAFARKLREPKYGAAADKVPADQLRKGDIVLVEAGDIIPCDGEVIEGGASVDESAITG
                     ESAPVIRESGGDFASVTGGTRILSDWLVIECSVNPGETFLDRMIAMVEGAQRRKTPNE
                     IALTILLIALTIVFLLATATLWPFSAWGGNAVSVTVLVALLVCLIPTTIGGLLSAIGV
                     AGMSRMLGANVIATSGRAVEAAGDVDVLLLDKTGTITLGNRQASEFIPAQGVDEKTLA
                     DAAQLASLADETPEGRSIVILAKQRFNLRERDVQSLHATFVPFTAQSRMSGINIDNRM
                     IRKGSVDAIRRHVEANGGHFPADVDQKVDQVARQGATPLVVVEGSHVLGVIALKDIVK
                     GGIKERFAQLRKMGIKTVMITGDNRLTAAAIAAEAGVDDFLAEATPEAKLALIRQYQA
                     EGRLVAMTGDGTNDAPALAQADVAVAMNSGTQAAKEAGNMVDLDSNPTKLIEVVHIGK
                     QMLMTRGSLTTFSIANDVAKYFAIIPAAFAATYPQLNALNIMRLHSPDSAILSAVIFN
                     ALIIVFLIPLALKGVSYKPLTASAMLRRNLWIYGLGGLLVPFIGIKVIDLLLTVCGLV
                     "
     gene            34385..34957
                     /gene="kdpC"
                     /locus_tag="IRB70_002397"
     CDS             34385..34957
                     /gene="kdpC"
                     /locus_tag="IRB70_002397"
                     /EC_number="7.2.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="K(+)-transporting ATPase subunit C"
                     /protein_id="HBC0632302.1"
                     /translation="MSGLRPALSTFLFLLLITGGVYPLLTTALGQWWFPWQANGSLIR
                     EGDTVRGSALIGQNFTGNGYFHGRPSATAEMPYNPQASGGSNLAVSNPELDKQIAARV
                     AALRAANPDASTSVPVELVTASASGLDNNITPQAAAWQIPRVAKARNLSVEQLTQLIA
                     KYSQQPLVNYIGQPVVNIVELNLALDKLDE"
     gene            34950..37634
                     /gene="kdpD"
                     /locus_tag="IRB70_002398"
     CDS             34950..37634
                     /gene="kdpD"
                     /locus_tag="IRB70_002398"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     KdpD"
                     /protein_id="HBC0632303.1"
                     /translation="MNNEPLRPDPDRLLEQAAAPHRGKLKVFFGACAGVGKTWAMLAE
                     AQRLRAQGLDIVVGVVETHGRKDTAAMLKGLAVLPLKRQAYRGRHISEFDLDAALARR
                     PALILMDELAHSNAPGSRHPKRWQDIEELLEAGIDVFTTVNVQHLESLNDVVSGVTGI
                     QVRETVPDPFFDAADDVVLVDLPPDDLRQRLKEGKVYIAGQAERAIEHFFRKGNLIAL
                     RELALRRTADRVDEQMRAWRGHPGEEKVWHTRDAILLCIGHNTGSEKLVRAAARLASR
                     LGSVWHAVYVETPALHRLPEKKRRAILSALRLAQELGAETATLSDPAEEKAVVRYARE
                     HNLGKIILGRPASRRWWRRETFADRLARIAPDLDQVLVALDEPPARTINNAPDSRSFK
                     DKWRVQIQGCVVAAALCAVITLIAMQWLMAFDAANLVMLYLLGVVVVALFYGRWPSVV
                     ATVINVVSFDLFFIAPRGTLAVSDVQYLLTFAVMLTVGLVIGNLTAGVRYQARVARYR
                     EQRTRHLYEMSKALAVGRSSQDIAATSEQFIASTFHARSQVLLPDDNGKLQPLTHPQG
                     MTPWDDAIAQWSFDKGLPAGAGTDTLPGVPYQILPLKSGEKTYGLVVVEPGNLRQLMI
                     PEQQRLLETFTLLVANALERLTLTASEEQARMASEREQIRNALLAALSHDLRTPLTVL
                     FGQAEILTLDLASEGSPHARQASEIRQHVLNTTRLVNNLLDMARIQSGGFNLKKEWLT
                     LEEVVGSALQMLEPGLSSPINLSLPEPLTLIHVDGPLFERVLINLLENAVKYAGAQAE
                     IGIDAHVEGENLQLDVWDNGPGLPPGQEQTIFDKFARGNKESAVPGVGLGLAICRAIV
                     DVHGGTITAFNRPEGGACFRVTLPQQTAPELEEFHEDM"
     gene            37631..>38197
                     /gene="kdpE"
                     /locus_tag="IRB70_002399"
     CDS             37631..>38197
                     /gene="kdpE"
                     /locus_tag="IRB70_002399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator KdpE"
                     /protein_id="HBC0632304.1"
                     /translation="MTNVLIVEDEQAIRRFLRTALEGDGMRVFEAETLQRGLLEAATR
                     KPDLIILDLGLPDGDGIEFIRDLRQWSAVPVIVLSARSEESDKIAALDAGADDYLSKP
                     FGIGELQARLRVALRRHSATTAPDPLVKFSDVTVDLAARVIHRGEEEVHLTPIEFRLL
                     AVLLNNAGKVLTQRQLLNQVWGPNAVEHS"
BASE COUNT         8841 a        10406 c         9766 g         9184 t
ORIGIN      
        1 gtttgttaat agtctttttt atcttgtatt gatcgtcatt gctgcataca ctacgcgcgt
       61 tttctttccc ttttgctggc tgctgaccgg aaagacaaaa ttaccctcgc aatacagggg
      121 gttgattaac gtctatattt caggacagcg ttatgcatca tctttcaagg cttgataaag
      181 cctttctgcg caaagggatc caactttccc gcgccaacaa tattgtttca ttatcttgtc
      241 catcaggtgc cagtgtccgc gtactgctgc cggacgaact gccgctggaa gaaaaagcag
      301 tgacacaact gcttgatttt gcagaagtga agataccaga ccatccaggt tacgtacgcc
      361 agacctgtgc gacgccagat tttcatcccg gcaatggcgt ccccgttggc gcggtagtcg
      421 cctctacgcc ggatttagtc attcctgcgg ccatcggcac cgatatttct tgtggcatgc
      481 ggctgctgac gaccggatta acacttgagc aagccgaagc gaataaagac gtcatcgctc
      541 agcggttaac gcaagtgcta ctgcaaaatg agcgcgatgt tccgttatcc gcacaggcgt
      601 tcaccgcgct ttttgatgac ggaccggcag agtgcatgtc agccttgcca tcagcaggtc
      661 tctggacacg cacgaatatc ccccgaatgg tacaagagat tgaccgctgc attgggctta
      721 acgagcataa cagtcattcg cgttatgccc cacccgccct gctggtaacg gaccgcccat
      781 tactccgcga tccttgtctt ggtacgccgg gttcaggtaa tcattttatt gaacttcagg
      841 tggttgatag cgtggttgat cgccatgttg cctggcaaca agggctgaaa acgggcgata
      901 ttgtggtgat gatccacagt ggatcgcgag atgttggctt ttacgtcgga agacgctgga
      961 tggatcgcgc ccgtgctgaa tggcccaccg gacataaaca tccacaaagc gggttatatg
     1021 gcctggcagg cggactggcg gaggaatatc tacaagcgat gggaatggcg gcgcgttacg
     1081 catggttaaa tcgcgtgacc attgcggaaa tggttcgcgt atgttttgcc gatttatttc
     1141 atcaggatga ttcacatctg gtggtggatg tgccgcataa catcatcctt cgcgagcatg
     1201 aaatgaatat tcatcgcaaa ggtgcaacac cggcacgcgc gggcaatctg gcgttaatcc
     1261 ccggttcaat gggcgattat tcgtggcttg cagtcggttg cggcaacccg gagtggctgt
     1321 ggtcttgcag tcacggagca ggacgcagcc agcgtcggca ggccatgcac tcacgcgcga
     1381 ctgaagagtc aacgttgccg tggcaatgcg tcacattgcg cgaagaacgg cgtattgaag
     1441 aagcgccagc ggcttataaa gatattggtc cggttatcga agcccaacaa gaggccggat
     1501 taattcatcc agcggttaga ttccgaccgt ggttaacgtt taaggcataa aaaaggccat
     1561 catatgatgg ccaaccatgt cgaaaccgac agcccttcgc cattcctgta gagggaagcg
     1621 gcgagggcta tttcttatta cagatattta tttcagaaca gttttcagtg cttcaccgat
     1681 atcagccagg ctgcgaacgg ttttcacgcc tgcggcttcc agagcagcga atttctcatc
     1741 cgcagtccct ttcccaccgg caatgatcgc acccgcgtgg cccatacgtt tgcctttcgg
     1801 cgcagtcaca ccagcgatgt aacccacaac aggcttggta acgtgctctt tgatgtacgc
     1861 agccgcttct tcttcagcgc taccgccgat ctcaccgatc atcacgatcg cttcggtctg
     1921 cggatctttt tcgaacattt cgaggatgtc gataaagtta gagccaggga tcgggtcgcc
     1981 gccgatacca acacaggtcg actgaccgaa accgtaatcc gtggtctgtt taaccgcttc
     2041 ataggtcagt gtaccggaac gggaaacgat acccacttta cccggtttgt gaatgtgacc
     2101 aggctggata ccgattttgc attcacccgg agtgataacg cctgggcagt tcgggccgat
     2161 catgcgaacg cccgcttcat ccagtttcac cttcacggtc agcatatcca gcgtcgggat
     2221 gccttcagtg atggtgataa tcagtttgat gcctgcatca atagcttcca gaatggagtc
     2281 tttgcagaac ggtgctggta cgtagataac agaagcggta gcgccagtag cagcaacagc
     2341 ttcacgcacg gtgttgaaca ccggcaggcc gaggtgggtg gtgccgcctt tacctggggt
     2401 tacgccgcca accattttag tgccgtatgc aatagcctgt tctgagtgga aagtcccctg
     2461 gctaccggta aagccctggc agataacctt ggtgttttta tcaattaaaa tggacattat
     2521 ttcccctcca ctgcggcaac aacctgctga gctgcatccg tcagaccttt tgctgcaata
     2581 atattcaggc cgctgtcagc cagtttcttc gcgccgagtt cggcgttgtt accttccaga
     2641 cgtaccacga ccggtacgtt aacacccact tccgctaccg cgccgatgat accgtcagcg
     2701 atcaggtcgc aacgaacgat accgccgaag atgttaacca gaacggcttt cactttgtcg
     2761 tcagagagga tgattttgaa cgcttcggtt acgcgctctt tggttgcgcc gccgccaacg
     2821 tccaggaagt tagctggttc gccgccgtgc agtttaacga tgtccatggt gcccatcgcc
     2881 aggcctgcgc cgttaaccat acaaccgatg ttaccgtcca gcgcaacgta gttcagttcc
     2941 cactgtgcag cctgtgcttc acgcggatct tcctgcgact ggtcacgcat ttcgcgcaga
     3001 tcaggctggc ggaacagtgc gttgccatca gcgcccagtt tgccgtcgag gcaaatcaga
     3061 tcgccctgtt tggtgatgac cagcgggttg atttcgatca gcgccaggtc gcgctccagg
     3121 aaaatggtcg ccaggcccat gaagattttg gtgaactgct gaaccagttt accttccaga
     3181 cccagtttga acgccagctc gcgtccttga tacggcatcg ggccagtcag cggatcaagc
     3241 gcaactttgt ggatcaggtg cggagtttct tccgccactt tttcgatttc cacgccgcct
     3301 tcggtggagg ccataaagac cacgcgacgt gaactacggt ctacaacggc accgagatac
     3361 agctctttag cgatatcggt cgctgcttca accagaatct ggttaaccgg ttggccattg
     3421 gcatctgttt gatacgttac cagacgcttg cccagccagt tttctgcaaa agcacggatg
     3481 tcttctttgc tgtttaccac tttcacaccg cccgctttac cgcggccacc agcgtgaacc
     3541 tgacatttca ctacccacgg accggcaccg atttttgaag cggcttcttc tgcttcgcgc
     3601 ggagtagtac aggcataacc caccggtgct ggtaagccat agcgggcaaa aagttgtttt
     3661 gcctgatatt catgtaagtt catgtgttct gtccatcctt cagtaatcgt tatcttttaa
     3721 accgtagacc gacaccctat ccacgtcggt ctacagtgca ggtgaaactt aaactactac
     3781 acgtccagca gcagacgcgt cggatcttcc agcaactctt tgatcgttac caggaagccc
     3841 acggattcgc gaccatcgat cagacggtga tcgtaggaca gcgccaggta catcatcggc
     3901 aggatctcaa cctgaccatt cacggccatc ggacgatctt tgatagcgtg catacccaaa
     3961 attgcgctct gcggcgggtt gatgataggc gtagacatca gggaaccgaa cacaccaccg
     4021 ttggtgatgg tgaagttgcc accggtcaga tcttcaaccg tcagcttgcc gtcacggcct
     4081 ttaacagcca gctctttaat tttcttctca atgtctgcca taccgagggt atcgacatca
     4141 cgcagtaccg gcgtcaccag gccgcgcggc gtagaaaccg ccatgctgac gtcgaaatag
     4201 ttgtggtaaa ccacgtcatc gccgtcgata gaagcattca cttccgggta acgtttcagg
     4261 gcttcaacca ccgctttcac gtagaaggac ataaagccca gacggatgcc gtggcgtttt
     4321 tcaaacgctt caccgtactg cttacgcaga tccataatcg gcttcatgtt gacttcgttg
     4381 aacgtggtca gcatggcggt ggagtttttc gcttccagca gacgctctgc cacacgctta
     4441 cgcaggcgag tcatcggcac acgtttttcg ctacgtgcag ccagggccgg ttgcgccgcc
     4501 ggagcagccg ctgccggagc agactctttc gccggggctt tcgccagatg tttttccaca
     4561 tcttcacggg tcagacgacc acccacaccg gtgcctttaa tggcgctggc gtcgaggtta
     4621 tgttcagcca gcaggcgacg gatcgccggg cttaacgcat cgttgttttg ctcttccaga
     4681 gacgcctgct ggcgttgcgc cggagtggac gctttctctt cagatttggc gctggtttct
     4741 ttacccgcgc tgttgccttc acgcaggcga ccaaggatct gacgagacgt taccgttgta
     4801 ccttcatctt ccagaaccgc atccagaatg ccgtctgctg atgccggtac ttccagtacc
     4861 actttgtcag tttcgatttc taccagcact tcatcacgta cgactgcgtc gccgggtttt
     4921 ttatgccagg ttgcgacggt ggcatcggct acggattcag gcaggtcagg gaccagaata
     4981 tctacgctac tcattgtgta tcctttattt attcgacgtt cagcgcgtca ttaaccagat
     5041 cttgttgctg tttctggtga acggacatat accctaccgc cggagaggcg gaggccgggc
     5101 ggcctgcata acgcagagaa gccccaaacg gaatcacttc acggaaatga tgctggctgc
     5161 agtaccatgc gccctgattg agcggctctt cctggcacca gacaaaatcc ttgacgtgag
     5221 caaactgctg caacacttcc tgcatcgctt tatgcgggaa cgggtagagt tgctcgatac
     5281 gcacaatggc gacatcgtgt tgattgttct tacgacgttg ttccagcagg tcgtaataaa
     5341 ccttaccaga acacatcact acgcgcttca cgcccttcgg atcaagctcg tcgatttcac
     5401 cgatggctgg caggaaggtg ccgttcgcca gttcttcgag gctggaaacc gccagcggat
     5461 gacgcagcag ggatttcggc gacatcacga ccagcggacg acgcatcccg cgcagcgcct
     5521 gacgacgcag catgtggtaa acctgtgccg gggtagacgg tacgcacacc tgcatgtttt
     5581 gctcagcgca aagttgcaga taacgttcca gacgcgcgga ggagtgctcc ggcccctgcc
     5641 cttcgtaacc gtgcggcaac aacatcacca ggccacacat ccggccccat ttctgctcgc
     5701 cagaagagat gaactggtcg ataaccacct gagcaccgtt ggcaaagtca ccgaactgtg
     5761 cttcccagat agtcagtgtg cgcggttctg cggtggcata accgtattca aacgccagca
     5821 cggcttcttc tgacagtacg gaatcccaga cacggaacgc gccctgaccg ttatggatat
     5881 gttgcagcgg cgtgtaagtt gaaccgttag actggttgtg gatcaccgcg tggcggtgga
     5941 agaaggtacc gcgaccggag tcttcacccg acaggcgaac cggaatgcct tcgtcaacca
     6001 gcgtggcgta agcgaggttt tccgcgccgc cccagtcgaa cagtttttca ccggctgcca
     6061 tcgcctgacg gtcgccataa atcttggcaa cgcgagactg catttcaatg gcttccggca
     6121 ccgtactgat gcgtttagcc aactcctgca ggcgcttcat ctcaactttg ttcgggtact
     6181 cttcgtccca ttcgtggttg aggtacggcg accaggtgaa ggagtgcatg ttcatcggac
     6241 gccactctgc taccacgcaa tcgccagcat ccagcgcatc gcggtacagg ttaaccatct
     6301 cggtggcatc ttccagcgtc gcgacttttt cctgctccag cttgtcagcg tagattttgc
     6361 gcggcgtcgg atgttttttg attttctgat acatcagcgg ctgggttgcg ctcggctcgt
     6421 cggcttcgtt gtggccgtga cggcggtagc ataccaggtc gatgaagaca tcacgtttaa
     6481 aggtgttacg gaaatcgagc gccagacggg taacaaaggc aacggcttcc ggatcatccg
     6541 cattaacgtg gaaaatcggt gcctgaacca tcttaccgat atcagtacag tacggcgtcg
     6601 aacgggcatc cagcgggtta gaggtggtga agccaacctg gttgttgata acgatacgta
     6661 ccgtaccgcc aacttcataa ccacgcgctt tcgacatgtt cagggtttcc tgaaccacgc
     6721 cctgcccggt cactgcggcg tcaccgtgga tggtgattgg cagcactttg ttgctgctcg
     6781 gctcatcgag tctgtccaga cgggcacgaa cagaaccgat aactaccggg ctgacaatct
     6841 caaggtgaga cgggttaaac gccagcgcca ggtgcaccag gccgccatcg gtctggaagt
     6901 cagacgagaa gcccatgtgg tatttcacgt cgcccgtgcc gaggtgttct ttatgtttac
     6961 cggcaaactc gtcgaacaag tcttgcggtt ttttacccag cacgttcacc agcacgttca
     7021 gacgaccacg gtgcgccatc ccgagaacca cttcgcgggt gccgctgttg ccagcgtggc
     7081 ggatcatctc tttaagcatc gggattaacg cgtcaccgcc ttccagcgag aagcgttttg
     7141 cgccagggaa ttttgcgccg aggtaacgtt caaggccttc agcggcggtc agttcgctta
     7201 agaagcgttt tttctcttcg ctattgaaag tcgcgcgacc agactcgata cgctgttgga
     7261 tccagcgttt ttcttcggtg ctggtgatgt gcatatactc ggcaccaatc gggccgcagt
     7321 aggtttgctt gagggcttcc agcagctcgc cgagtttcat ggtttctttg ccgctggcaa
     7381 atgaaccgac gttgaaggtc tcctggaagt ctgcttcggt cagatcgtgg aaagacggat
     7441 ccagatcggc cactttatct tgctgccaca gtcccagcgg atcgagattc gcatgctggt
     7501 gaccacggaa gcggtatgcg ttaatgagct gcaggacttt aacctgcttc acattggtgt
     7561 cagggtcgga gatcgttgaa gagtaacgtg aagcgtcttt cgccaggcgg cggaaatatt
     7621 cacgcgtttg agagtggaat tgatccggtt tgactcccgt accaggtaac tgctggaacg
     7681 tcgaacgcca gttagcgtca accgagtcag gatcggttaa gaagtcttca tagagctgtt
     7741 ctatccagct ctggtttgcg ccagagaggt aagaagagtc caaccaggct ttcaaagcgc
     7801 tgttctgcat cgtgatccct taagcatctt ttttatgctt acttcgccgt ggatactacc
     7861 acgcacagtg atgtgcgtgc cggggttcac ttgcgagctc ttgtctacgt agtggctcgc
     7921 gaaggaacct ttaaaaactg tcttagtgtc aggggcagtt tttaaagatt tcctgaatag
     7981 ccgggggatt tccccggcat caacatttaa ttacgcatta cgttgcaaca acatcgactt
     8041 gatatggccg atggcgcgcg tcgggttcag ccccttcgga catacactga cgcagttcat
     8101 gatgctgtga cagcggaata cactgaatgc atcgctcaaa ccgtcgaggc ggctgtcagt
     8161 ctcggtatca cggctatcga tcaggaaacg atatgccgct aacaagcctg ccgggccgat
     8221 aaacttatcg ggattccacc agaaagacgg acaagaggtt gaacaacatg cgcagagaat
     8281 acattcatac aacccgtcga gtttttcgcg ctgctctggc atctgtaaat gctcgcgagc
     8341 tggcggattt tgtccattat tcaacaggta aggcttaatt ttctcatatt gcgcatagaa
     8401 ttgtcccatg tctaccacca aatcgcggat caccggtaaa cctggcagcg ggcgaatcac
     8461 aatcttcttg cccggctggt tgagtgccga aatcggggta atacaggcca gaccattctt
     8521 accgttcatg ttcagaccgt cggaaccgca cacaccttca cggcaggagc gacggaacga
     8581 caggctggga tctttctctt tcagctggat aagcgcatcc agcagcatca tgtcgcgacc
     8641 ttcttccgct tccagggtgt aatcctgcat acgcggagca tcatcaacat ccgggttata
     8701 gcgataaatt gaaaactcga gtctcatttt cctgtctccg cattagtaag tacgaatctt
     8761 cggcgggaat gccgggcgca gtttcggttc catgttgacg cttcggcgcg tcatggattc
     8821 cgactctggc agatacaggg agtggcacag ccagttttca tcatcgcgat ccgggaagtc
     8881 gaagcggcta tgcgcgccac ggctttcggt acggaagttg gcagaaacag ccgttgcata
     8941 cgccgtttcc atcaggttat ccagttccag gcactcaacg cgctgggtgt tgaactcgct
     9001 ggaagtgtca tccagacggg catttttcag acgctcgcgg ataactttca actgctcaag
     9061 ccctttcgcc atcgcatcac cttcacggaa gaccgagaag ttatgctgca tacattcttg
     9121 cagtgcttta cggatcgcca ccggatcttc accgttacgg ttattgttcc agcggttcag
     9181 gcgatccaga gacgcttcaa catcagactc gctggcatcg cgcagtgcgc cctgctcggc
     9241 gatagactct tgcagatgca gacccgctgc gcgaccaaag accaccaggt ccagcagcga
     9301 gttgccgccc agacggttag cgccgtgtac cgatacacaa gcgatttcac caacggcaaa
     9361 cagccccgga acaaccacat cttcgccttt ctcgttcacc gtcagcgcct gaccggtcac
     9421 tttggtcgga ataccgccca tcatgtagtg acaggttggg ataaccggaa tcggctcttt
     9481 caccggatca acgtgagcga aggtacggga gagttccaga atacccggca gacgggattc
     9541 gagaacttct ttacccaggt gatcgagttt cagtttcgcg tgtggccccc acggaccatc
     9601 acagccgcga ccttcacgga tttcgatcat gatggaacgc gccaccacgt cacggcccgc
     9661 caggtctttg gcgttcggcg cataacgctc cataaagcgt tcgccatgtt tgttcagcag
     9721 ataaccgcct tcaccacggc aaccttcggt gaccagtacg cccgcacctg caatgccggt
     9781 cgggtggaac tgccacattt ccatatcctg caccggtacg cctgcgcgga tagccatgcc
     9841 gacgccgtcg ccagtgttaa tgtgggcgtt agtggtggac tgataaatac gccctgcccc
     9901 gccagtcgcc agcacggtag cgcgggcttt gaaataaacc acttcaccag tttcgatgca
     9961 caatgcggta caaccgacca ctgcgccatc ctggttcttc accagatcca gcgcatacca
    10021 ctcggagaaa atggttgtat ggtttttcag gttctgctga taaagggtgt gcaacagtgc
    10081 gtgaccggta cggtcagctg ccgccgcagt gcgtgccgcc tgctcgccgc cgaagttttt
    10141 cgactggccg ccaaacggac gttgatagat acgaccatca tcaaggcgcg agaacggcag
    10201 gcccatgtgt tcgagttcca gaatcgcttc cggcccggtt ttacacatat attcaattgc
    10261 gtcctggtca ccgatatagt ccgaaccttt tacggtgtcg tacatatgcc attcccagtt
    10321 atcttcatgg gtattaccca gcgcaacggt aatgccgcct tgcgcagaca cggtatggga
    10381 acgggtcggg aagactttag agagcagcgc acaggtctga ccgctctggg aaatttgcag
    10441 cgccgcgcgc atacctgcgc caccggcacc aatcacaact gcatcaaatt ctctgactgg
    10501 caatttcatc acacacccca caccacaacg aatccataaa tcacgtaaac caccagagca
    10561 acgacaatca ccagttgcag catcaggcgc aaggccagcg gtttaacgta gtcggtcaac
    10621 acctgccaca tgccgatcca ggcatgaatc aagatagaaa acagcgccag cagggtgaac
    10681 actttggtga acgcagaggc gaagaaacca atccagactt catatgtcag ctcgccactg
    10741 gtagcgaaaa aaccgaccat ataaatgatg tacagcgtca ggacgatagc ggtagcgcga
    10801 acgaggatga aatcatgtac gccattgcgt cctaatgcgg aggcgttgct taccatacga
    10861 ggactcctgc gagaagtgaa agcacgacag taataacaaa ggagattttg gcggagcgtt
    10921 tacccgcttc gaatgtttct tccagatagc caaaatccat catcatgtgg cgaataccta
    10981 cgacgacgtg atacgccaga gcggtaagga tgccccacat gataaatttg acgaagaagc
    11041 tgcccataat cgcagaagct tgctcgaaac cttcagggga agagaggctg gtacccagaa
    11101 gccacagcag gatgcccact gcaacaaagg tgatcacacc ggaaacgcga tggagaatgg
    11161 acgctatcgc cgtgacgggg aaccggatgg tctgtaggtc cagattaaca ggtctttgtt
    11221 ttttcacatt tcttatcatg aataacgccc acatgctgtt cttattattc cctggggact
    11281 acgggcacag aggttaactt tctgttacca ggagacgtcg ggatttcctt cctccggtct
    11341 gcttgcgggt cagacagcgt cctttctata actgcgcgtc atgcaaaaca ctgcttccag
    11401 atgcgaaaac gacacgttac aacgctgggt ggctcgggat tgcagggtgt tccggagacc
    11461 tggcggcagt ataggccgtt cacaaaatca ttacaattaa cctacatata gtttgtcggg
    11521 ttttatcctg aacagtgatc caggtcacga taacaacatt tatttaattt ttaatcatct
    11581 aatttgacaa tcattcaaca aagttgttac aaacattacc aggaaaagca tataatgcgt
    11641 aaaagttatg aagtcggtat ttcacctaag attaacttat gtaacagtgt ggaagtattg
    11701 accaattcat tcgggacagt tattagtggt agacaagttt aataattcgg attgctaagt
    11761 acttgattcg ccatttattc gtcatcaatg gatcctttac ctgcaagcgc ccagagctct
    11821 gtacccaggt tttcccctct ttcacagagc ggcgagccaa ataacaaacg ggtaaagcca
    11881 ggttgatgtg cgaaggcaaa tttaagttcc ggcagtctta cgcaataagg cgctaaggag
    11941 accttaaatg gctgatacaa aagcaaaact caccctcaac ggggacacag ctgttgaact
    12001 ggatgtgctg aaaggcacgc tgggtcaaga tgttattgat atccgtactc tcggttcaaa
    12061 aggtgtgttc acctttgacc caggcttcac ttcaaccgca tcctgcgaat ctaaaattac
    12121 ttttattgat ggtgatgaag gtattttgct gcaccgcggt ttcccgatcg atcagctggc
    12181 gaccgattct aactacctgg aagtttgtta catcctgctg aatggtgaaa aaccaactca
    12241 ggaacagtat gacgaattta aaactacggt gacccgtcat accatgatcc acgagcagat
    12301 tacccgtctg ttccatgctt tccgtcgcga ctcgcatcca atggcagtca tgtgtggtat
    12361 taccggcgcg ctggcggcgt tctatcacga ctcgctggat gttaacaatc ctcgtcatcg
    12421 tgaaattgcc gcgttccgcc tgctgtcgaa aatgccgacc atggccgcga tgtgttacaa
    12481 gtattccatt ggtcagccat tcgtttaccc gcgcaacgat ctctcctatg ccggtaactt
    12541 cctgaatatg atgttctcca cgccgtgcga accgtatgaa gttaatccga ttctggaacg
    12601 tgctatggac cgtattctga tcctgcacgc tgaccatgaa cagaacgcct ctacctccac
    12661 cgtgcgtacc gctggctctt cgggggcgaa cccgtttgcc tgtatcgcag caggtattgc
    12721 ttcactgtgg ggacctgcgc acggtggtgc taacgaagcg gcgctgaaaa tgctggaaga
    12781 aatcagctcc gttaaacaca ttccggaatt tgttcgtcgt gcgaaagaca aaaatgactc
    12841 tttccgcctg atgggcttcg ggcaccgcgt gtacaaaaat tacgacccgc gcgccaccgt
    12901 aatgcgtgaa acctgccatg aagtgctgaa agagctgggt accaaagatg acctgctgga
    12961 agtggctatg gagctggaaa acatcgcgct gaacgacccg tactttatcg agaagaaact
    13021 ctacccgaac gtcgatttct actctggtat catcctgaaa gcgatgggta ttccgtcttc
    13081 tatgttcacc gtgatcttcg cgatggcgcg taccgttggc tggatcgccc actggagcga
    13141 aatgcacagt gacggtatga agattgcccg tccgcgtcag ctttacaccg gctacgcgca
    13201 gcgtgatttt aagtcggata ttaagaagta aaaatgacac cgacgaaacc ctgcgtgttc
    13261 acgcagggtt tttagttcta caccaacagc aaagatattg ccgggatata ggtaataacc
    13321 aacagcagta aaataagact aaccagtagt ggcaccgctt ctcgcataaa ttgcccgaca
    13381 gaaacctgca cggtattaca taccagcagc atcaccgttc cgacaggcgg tgataacgtt
    13441 cctaacgata agttgaggat catgatgatg ccaaaatgca ccggatcaat gccaaaatga
    13501 gccaccacag gtttaagtaa tggaactaat atcagcagga tggcactacc ttcaagaaac
    13561 atgccaagca ccagcagcaa tagattgata atcaataaaa agacgtattt attatcagtc
    13621 agagatgtca caaactccgc aaccgtgata cctgcccgct caagggaaaa tatccagccc
    13681 agcgcggcac tcgccataat gattaacatg accgatgccg tcgaacgcgc cgtctctgag
    13741 agtgctgtaa atacatggct gattttcagt tcgcgataaa ttacaaaacc aataaacatc
    13801 accaataata ctgctacggc tccagcttcc gttggcgtaa agatatttgc ccgaatacca
    13861 ccgataaccg caacaattaa gaacagtgct ggccaggcct gcaccagcgc cactgacact
    13921 tctttcggtt ttggccagtg ttcgctggaa ggttttaaac cgcgccgaat agctaccagc
    13981 catacagtga caatcaacat ggcggaacac agcagaccgg gcaggatccc ggccataaac
    14041 atggagccga tggagacatc cgccaccagt ccgtaaagga tcagtgcaat acccggtgga
    14101 ataattggtg taatcagcga accacttgcc gttatcgccg ccgcaaagcc acgggaataa
    14161 cctttctgtt ccatttccgg caccatcatg cgcgataaca tcgcagcatc cgccaggttt
    14221 gaggcgctaa cgccgcccat catggtactg accagaatat tagccccacc cagaccaccg
    14281 cgcattctgc caatcaacac gttggcaatt tgcaaaatac gcgcggcaat accggtatag
    14341 ctcattaacg tgcctaataa gataaaaaat ggaatagcta acagcgaagg ggtttgcgtc
    14401 gtggcaatca aacgctgaat tgctaccatt aacggcacat ttgaatagca aaggaagtag
    14461 gtcagaatgc cgcaaaacat cgccagccat accggcatat tgataaataa acagatgaac
    14521 ataagcggaa tgatcattag ccagttatcc agccagcttc ccgccagtaa ttcactcaat
    14581 gctgtcatta ttcaccttcc ttgcgtggcg ttttcttgat caggtgtaag gcagtaaaac
    14641 aggcgatacc gattgcacca accgtgaccg caatatcgat ccaaaaccag gatattttta
    14701 atatttgcgt agttttaaat gctgttccgg cagctaattt ccatgctgac caggccatca
    14761 cactcagtaa aacaatagat atcagagaga caaataacgt taaaacacgt tgcacgcgtg
    14821 gtgtcagtgc atcagctaaa aatggaatcg acaaatgggt attatcccgc tcggcaacga
    14881 ccgcaccaaa catgactacc caaatcatta ataaaccgga aacctcttct gtccactgta
    14941 atggcatatg aaaacagtaa cgcattatta ccgcagcaat ggtcatgatt accaatataa
    15001 agagcgttaa taccgcagca acttcaatca ttttccctaa aagacgcata aacacctctg
    15061 ctcttaacgg tcggtgccga aacaccgacc agtccttatg ccatgaagtt atttcagctg
    15121 ttgctgaata gtgtcataca aaccaggggt ccattccggg aattgttgat agacttttaa
    15181 ggctttttct ttgaaagggg cgacgtcagg atagatgatt tccacgccct gctcctgcat
    15241 ggttttcaac attgtcgcac cctgctcagt ggtaattttc tggctatata aaccagcttc
    15301 atacgctgtc tggtgaataa tatctaactg cgcaggtgtc agggtactga aaaacgcttc
    15361 accacccaac cataatgatg tattggtcag atagttcacc attgacagat atttcgcctg
    15421 ctcatgcagt ttttgcccat acagaacaga aaccgggttt tccacaccat cgatcatccc
    15481 ctgcgtcagc gccggataaa cgtctcccag cggcattggc gttggggttg cgcccattgc
    15541 ttcaatggct ttaatctgca taacgttatt cggcacgcgg atcttcatcc ctttcaggtc
    15601 ttcaggtgta cgaatcggtt ttttagcaat gatctgcctg gtaccgtaca gatagttgct
    15661 catgacaata tgcacacctt tttcccgcag tttctgttct ttttgtttaa accagtcact
    15721 ggcataaatc gcaaacagtt tctgcggatc ttcgcttaaa taaggcccaa acaatattcc
    15781 caggtctgca tcgtagtcag ttaaaaatcc cacatcactg atggtgataa tattcatccc
    15841 catcaacgct tgttcagtaa tatcttgttt agaacctaac tgtgaacttg ggtaaagttc
    15901 gaaaacaata tctccattgc tttttttctt cacaagttct gcccagtgct tcactactgt
    15961 atccgctggc tcgccggggt tactttcata ggcgattttg atagtgaccg gtgcggcatt
    16021 cagcatcgga cttaataaag cgaaaagaaa taaaaatggt gtcagtaatt ttttcattat
    16081 tattacctgt aagagcttta tcaattaacg gggatctgcc cgacagactg cacttttgct
    16141 gtaatcaaat gctttatacg ttaaaacaaa ctcctgatgt tccagtcgtt ctgcggcaca
    16201 atattgaccg ttggcgacat gttcaatcac ttgcataata tcgtctgcaa tatcgtcgag
    16261 cgttgcgcct tcgctaatta cacgaccggc attaacgtcc atatcgtcag ataaatgctc
    16321 ccacgtctgc gggttattac acactttaat aataggagcg atcactgaac caataactga
    16381 accgcgacct gtggtaaata acaccatatg acagccagag gcgataagtt ccagtgcttc
    16441 tgaggaatcg ttaatattcg gatacccaaa acgaggttca ccatcaggca ccacgtccat
    16501 caaccaaagc ccaggaaagg gcgcttgttg cgtcggcaaa ataacgccag caatcagcgc
    16561 atcgcccgac ttggtataag ccccgaggga tttttcttcc tgagtggtta agccaccttc
    16621 ggcattacca ttagaaaaac tccccagccc catcaaactg taataacgtt cggcttttgt
    16681 cattgccact tcgatggcat cacgtgcctg cgaactagcc gcgcgcgaca tcatatgctg
    16741 ctcacaacca agcaactcac cgctttcttc aaaaatacag gtagcccctt tctccagcag
    16801 ttggtcaaag gcacgtccta ctgccgggtt acccgtgata ccactggtgc catcggagcc
    16861 accgcagata gtaccaacca ccaggtcgct ccagttcagg atacaacgca gtgtatccgc
    16921 aagctgttcc agcatttcag cgaccaactg cttacccaga gtaatggtgt tggtcgtgcc
    16981 tttattttcc tgaatgacca gcgtatggca cggtcgccca ctttctcgta cttcttgctc
    17041 cagccgacgg cgatcaaaat tctcgcaccc cagcgaaata atcagtacac cacctacgtt
    17101 gctatgaatc gccagatttt ttaccagacg atagccataa tcgctgggat aacaacctga
    17161 aaaaccaaaa tactgcacgt cgtgacaagg aaatccttcg gcaatctttt tagcgacatg
    17221 gctggcacac tccaccataa agattacctg cacagtatta cgaatacccg gtcgaccatt
    17281 ttgccgtaca taaccttcca ttatgctttt tcctctggct gatagccggc atcatcatga
    17341 tgaaaaatgg cgatggcatt gctggcaaga ttatgggaat gcacatgttc acccatggca
    17401 atatcgcgag tggcgtgtcc gataatggcg ccgtatttca gaatcgaatc accattgttc
    17461 agcgcttcgc aggccagttt gtgacccagg gtaacggaac tacaggccac catttccccc
    17521 tcatcccacc agacaatatc gccactggtg atgtcattca gcgcgactac acagttatct
    17581 ttggcatgta gctttaacgc acgtttgcgc ataattcctc cgtacatcag aagccgatca
    17641 atgcgccgcc atccaccacc agcacctgac cactgacaaa cgccgctgcg tctgaagcca
    17701 gataaaccgc agcccaaccg atatcttccg gcttgccgaa ttttttcatc ggggtacgac
    17761 ccaggatttt gttacggcgt tcgtcatcac cttcaatggc cttacgcaac attggtgtat
    17821 cgatccagcc tggcgcaata ccgttgacgc gaatcccatg aacggcaagc tccgtggtca
    17881 taccgcgaat catgccgaga taggctgact tcgctgcgct gtagccagta accagaggct
    17941 gcccaagaaa tgaggtcatc gatgcagtaa aaagcacaca gccttgaccg cgttgtttca
    18001 tatgcggcac cagcgctttg gttaacgcaa atgcgccgac tacgtgaacg tcgagtactg
    18061 actcaaaatc actgacgctc atctcttcaa tcggtttttt gcagtgattg cctgcgttat
    18121 tgaccaggat atcgatagcc ccgtgttcgc taataagcgc atcaactttt tcctgcgcgg
    18181 ctgcggtatc cccgacatcc atttgtatcc aactggcctg cgaccccaat gttccggcgg
    18241 tcgcttgcgc cagctcgccg ttcaggtcag caataatgac cttcgcccca ctgactatca
    18301 tgcatttcgc cattgccagc cccagtccac tggccgcccc tgtaatcagc gctgttttgt
    18361 tatgtaaaga aaaagcattc atggtgtcgc tccttaaagg tcaatgagga ttttggtata
    18421 cgcgccggga tcacttgccc agtcgctaaa agcgtgatca gcctgttcca gcgggtagtg
    18481 agcactcacc agattgctga ccggataacg cccggactcc atcaatgcca gcacggcccg
    18541 aaaatccgcc acggtggcat tgcgcgaacc acggatatcc agttctttca tcaggaactg
    18601 cgcactctga taactcactg gctgtttggc gtaaccgaca taaaccacac gaccgctaaa
    18661 cgccaccaac cctgtagcct gttcaatggt ttgttgatta cccaccgctt caatcaccac
    18721 ttccgggccg cgaccgtcat ttaacagcac cagttctgcc gccacgtcac attgctgcga
    18781 attaagaaaa cgttgcgcac cgcattccag ggcaatgttc tgcttgcgat catcaatatc
    18841 gatagcaatt acgcgcgccc ccatggcgga tgccgcggcg atagcgccaa ggccaattac
    18901 cccacaaccg ataactgcga cccattcacc cacattaatt tgcgcacgtc tggccgcatg
    18961 tagtcccacg gccagcggtt ctaccagtgc taactcatca acacttaagg cattacagac
    19021 aatgacttta tgtgcaggca tcgtcagttg ttgcgccatc cccccctgac gttgcacacc
    19081 aagagtttgg ttgtttttac aggcgttagg acgaccgctc agacaggagc tgcacacgcc
    19141 acactcagtg caaggcagaa cgaccacccg gtcacctggc ttgatcgccc ctgccatatc
    19201 gccagttgcc agcaccgtgc cgccaatttc atgccccgga atacagggat aattaaccag
    19261 cggattcagt ccccgccatg tattgaggtc agaaccacac agtccgacac gctcaacatt
    19321 gattagcact tctcctttac cgcagacagg ttcggggata tcaacaaatc gcgcctgact
    19381 tccctgctca atggttaatg ccttcattca ttgctctcct tacattacgc cgaaggtttc
    19441 aaaggcctgt accgtgctca tgccatcact gatggctttg cgcacttcac tttcagttgc
    19501 cactttttcc agggcctggg taataacttc tttctcaaca acctggggaa taatcagtaa
    19561 tccatcacga tcaccaaaca cgatatcgcc cggattcacc cgcacgccgt gaaattcaat
    19621 aggtacgccg aagtcgatga ccttgccgcg cggaccttga tcttgtgcgt aagtgccatg
    19681 acaaaaggtg ggaaatttca attcaagaat ttcagcagag tcacgggcgt aaccatcgag
    19741 taccgcacct gctgctttca gatgcatggc acgggtagac atcaacccgc cccacaaggc
    19801 atagcgcaga gagctgcccg tagtgatgta aacatcgttc tctttgaggg catccagcgc
    19861 ttcaaacatg atgccaaacg gtttttcgcc aatcgccgtc ttacccgacg tcgatttggt
    19921 ttcgtaaacg tccgactcca gcaccggcat tgcccggcct gccaccaccg tattcacatc
    19981 cagcggcttg attgccggag aaacaaactg gtgcatatag cccagcgtgt cgagaatatc
    20041 gccaaccacg gcggtaaata gccgggtttt catcaaagca aaaagttcgt tatcactctt
    20101 ccacattatt ttcaccctgt aagcctgttt aacaggttta cagggtaagg agaaaaagcg
    20161 cacaatactg cgaagggcgt cacgaaaaag ttgtgtattt actatttctt cgccactctt
    20221 tcacacaata tgtctttgat tcgcactgca tggcgggcgc acaggcgcag tagtctattg
    20281 ataatcaagg gttctggagg aaaatatgaa ggatacagtc ccggtattct ggattttacc
    20341 gaccaggaaa aagtacaaca ggagtaaaaa tgagtgagag tgcgttattg accagcgtaa
    20401 cgttatcgtc acaggtcaaa aatcatattc ttaatctgat cgccgaacaa aaattgacac
    20461 cggggatgcc agttcccagt gaaattcagt tgattcagaa attgggcgtc agtcggggta
    20521 ttgtgcgtga ggcctatcgt tcacttgccg ccctggggat tctggaaacg cacagcggta
    20581 aagtgccacg gatcaaaaaa tttgatgatg aagtgctgcg cgtggtgttt ggatttgccc
    20641 tggcgaccga acaagtaaca acagagcaaa ttcttcaagt acgtcgctgg ctagagttgg
    20701 gcgttgtgga agctgctgcc cgtaatggcg gagaagaaga ttttgctaac ctacgggctg
    20761 aaatggcaaa aatccgcgaa cagttcgatg atgtcgaaag ctttatcacc catgacatcc
    20821 gcttccatca gttactcgcc gttgcctcaa aaaatccgct ttttatgatg ttattgcagg
    20881 cattacatca gcaattgcgg caatccatcc aggagggatt aaacgcccaa agcgatcaga
    20941 aagagtatgg caatcacatc atcacactac accagaaaat ctgcgacgct gtgtgtgcca
    21001 gagatgtcga aacggcgact caagccatga aatcacactt cgacagcccg gtcagtgcac
    21061 tgatcaataa ttcctcgcca taagacttat ttcagttcaa tcgtttactc ttccctcttt
    21121 tacaaatgag agggagacaa cggtacttaa tacgcccttt agccaaaatc tgtctttttc
    21181 ttgattaccg ctattttttc gttgaggcgc attctttatg ctgtatcgat acaccaaagg
    21241 taagttaaac agggagtgac ggatgccagt tttgcagtgg ggaatgttat gtgttctgtc
    21301 acttctcctt tctattggct tcctcgcttt acatctcccg gcggcactcc tgcttggccc
    21361 gatgatcgcc gggatcatct tcagtatgcg cggagtcact ctgcaacttc cccgctccgc
    21421 ttttctcgcc gcccaggcca ttcttggctg catgattgca caaaacctca ctggttcgat
    21481 tctcaccacg ctggccgtca actggccgat cgtgcttgcg attttactgg tgacgctgct
    21541 ttccagcgcc atcgtgggtt ggttattggt gcgctatagc tcactgcctg gaaataccgg
    21601 tgcctggggt tcttctcctg gcggcgcggc ggcaatggtc gctatggcgc aagattacgg
    21661 cgcagatatt cgcctggtgg cgtttatgca atatctgcga gtgctgttcg tcgcgggggc
    21721 cgctgttctg gtcacccgca tgatgctggg tgataacgct gaagcggtta accagcagat
    21781 cgtctggttc ccgccagtga gcattaatct cctgcttacg attatgctcg cggtcgttgc
    21841 cggtacggcg ggatgcttgc tacgtcttcc ttccggcacg atgctcatcc cgatgctggc
    21901 gggcgcagtg ctccagtctg gtcagctcat cacgattgaa ctcccggaat ggctgctggc
    21961 gatagcatat atggcaattg gctggcggat tggtcttggt ttcgataaac aaatattact
    22021 gcgggcattg cgcccactgc cacaaatcct gctgtcgatt tttgctctgc tggctatttg
    22081 tgcgggtatg gcgtggggac tgacccggtt tatgcacatt gattttatga ctgcctacct
    22141 cgccaccagc cccggcgggc ttgataccgt ggcggttatc gccgcaggga gcaatgccga
    22201 tatggcgctc attatggcga tgcaaaccct gcgcctgttc agtattttgc tgacggggcc
    22261 tgccatcgca cggtttattt caacctatgc gccgaagcgt tcggcctagt gctggcagcc
    22321 agggcaccag taaaacgggc gagatgacag cgtggttttc tcaatgatgc cgccacagcg
    22381 ttcgcacggt tcgctatcac gatgaaaaac cttaaagcga aacagcgccc catgatgctt
    22441 attctcatcc acctgccccc gcgtagcgta agaaagtcga ggaatatcca gtaacgcgtg
    22501 tgcgagtgca tccagttgcg ccgcattgag atctttcgct ttatgatttc cagtcaaccc
    22561 aacctgccag aggatctcca cccgcaaata attgccaagc ccagccagaa acgcctgatc
    22621 gagcagtaat ccagcaaact gacggttacg aaagcgcggc gacaataatc gttcctttac
    22681 cacctccggc gtcagattcg gatccagcac atcgggacca atgcgttgta aaaacggatg
    22741 cgtggtcagt tgttccgggg tcaacatctc aatatccgag gcgctataaa gcagaatggt
    22801 tttgtcagcc gtttgcagtt ttacccgcaa tactcgcgtg gtctgcggct ctttgccggt
    22861 atcaaccacg cgccagacgc cgtaaagctg attatggctg tagagcgtta attcgttgga
    22921 aaaatgagtt aacaacgcct taccacgcgt ttccacatgg gtaacgtgtt gaccgataag
    22981 ttgtgattga taagatttta actgcgggaa ggcaaaccag acatcagtta gtggtttgcc
    23041 tttgatcgcc gcctccaggt tatccgctgc acggcggatc tccgggcctt caggcatggt
    23101 gatatccttt tttcattctt tattaagcgg ggttatgctg cgacaacaat ccccttttca
    23161 gcaaatgtag ctcgtaatcg gcgggcgaac gccagtgcgt gctcgccatc gccatgcagg
    23221 cagaccgttt gcgccgtgac cgttgcccat tcgccggtga tacttttgac tctgccgtgt
    23281 tgcaccatct ccaacgtttg cgccagcgcc tgttcttcgt tttcaatcaa cgcgcctggc
    23341 tggcttcgcg gcaccagcga accgtctgcc tgataaccgc gatcggcaaa cacttcctcg
    23401 cgcgttgtca ggccatattg cttgcctgca cgaatcagct cgcttcccgc cagcccgacg
    23461 agaatcaatg ccggatcgca agcgtatacc gctctggcga tggcgtctgc cagttgtgcc
    23521 tctttcgccg cctggttgta taacatgccg tgcggtttga catgacgcat tacgccgcct
    23581 tgcgcacggg caatcgctgc cagcgcgcca atttgataca gcgtctgggc gtaaacggtt
    23641 tctggcggca gctgcatagc gctgcgacca aaattttccc tgtcaggaaa actcggatga
    23701 gcgccaatcg cgacaccatt ttttattgct tcacgcacgc aagcgtgcat gatttgcgca
    23761 tcgccagcat gaaatccaca ggcaatattg gcagaggaaa ccagcgttaa tagctctgcg
    23821 tcgctgacac agccttcgcc cagatcggcg ttcaggtcaa ttttcattgt gcagccgcca
    23881 cgctaattgt tcgaaataac gttgctgatc ttgccgtgct ttcagtgcct cttccagtga
    23941 acactggaca aaatgaatcg gctgaccgag cggaatttgc gccagatggt acatatcagc
    24001 ctcaatgata caggcaatac gcggataacc accggtggtc tgtgcgtcgt tcatcaatac
    24061 aatcggctgg ccgttatgcg gcacctgcac cacgcccggc aacaaaccat gagataacag
    24121 ttcgcgatcg gtggtgcgtt ttaaaatttg cccctgtaag cgatagccca tccggttact
    24181 ttgcgagcta agctgccagg gcgaacgcca gaatgcatcc tgcgaggcgc gatcgaactc
    24241 atgatattcc ggccccggca aggcgcgaat gcggttgccc cacagcagct gtttaacgcc
    24301 cagcgcttcc ataaaatcac gcttcgcttt gccaatcggg agtcggtcac catccttcag
    24361 taaacggcct tccagcccgc caatccccac tttgagatcg gtgctgcatg accccattac
    24421 cggcggaaca tcaataccac ccgcgaccgc cagataactg cgcatcccgt gctgcgggcg
    24481 tttaagcgtt aaacgctggc ctgctttcat cggcaatcgc cagccggtcc agacggcgtt
    24541 atcatccagc cgcgcttcgc aaccggcacc cgtcagagca aaccacccat cagtttcgaa
    24601 ctcaaccgtt aactgaccga gcgtgatctc cagcgcgggg gcattggcgt cattacccac
    24661 cagcaggtta gcaatgcgca gcgcaggcat atccagtgcg ccgcagtggc tgatacccga
    24721 ctggcgaaaa ccgtgacgac cgccatcttg cacagtggta tacatgcccg cacgaataat
    24781 cttcagcata ctccctcctt ttgcggtaca aagcgcacgc tgtctcccgg acgtaataag
    24841 atgggttcgt cacgcgccgg atcaaacagg ctgagtgagg tatgaccaat caactgccag
    24901 ccacccggcg ttgccagcgg ataaacaccg gtctgcggcc cgccgatccc gacagaacct
    24961 gccggaacga gcaagcgcgg ttcagcgcgc cgtggcgtgt gtagttgttc cggcaaactc
    25021 ccgagatacg ggaagcccgg ttgaaaacct aaaaaccaga ccacgtattc cacggaggag
    25081 tgcaattcaa caacctgttt ctcactcaac ccacaatgcg ccgcgaccac cgctaaatcc
    25141 ggtccgcctg caccaccgta aaccaccgga atttcaataa agcgagactc cggctccagc
    25201 gcctcactct cctcccacca gcgttgcaaa cgctctatgg catccagcgc cagcgactca
    25261 ggattacgta aaatcaccgt gatattgttc atgccgggaa tgacttcaac cacattcggc
    25321 atatccacca gacgctgcgc cagtcgccag atccgtttct ggctagccag cgtcaccggc
    25381 ggttccagct ccagcactac cgccgtttca cctatcagat aacaacgcgc tcgttgcact
    25441 ttcgatccct ctgattattc gttatgcagg attaggaata tcaataaagg tcacatcaag
    25501 atcggtattt tcattcagcc actcgctcaa cgcgcgaata ccaccgcgtt cagtggcatg
    25561 gtgacccgca gcataaaaat gcaatccctg ctcgcgggct gaatgaatgg tctgttcaga
    25621 aacttcgcca gtaataaaag catccacgcc aaaacgcgcg gcgctatcga taaaactttg
    25681 cccgcccccc gtgcaccagg cgacgcgctg gaccacctca ggtccggtat cgccacacca
    25741 taacggctta cgtcccagac gcgcttcaat ccaggaggcc agttccagtc ccggcacagg
    25801 catggtcagt tcgccccacg gcaccaacgg ctcaatttcg cccatgaccg tgatccccag
    25861 taacgccgcc agttgtgcgt tattacccag ctccggatgc gcgtccaggg gcagatgcca
    25921 gccatacagg ttgatatcat tcgccagcaa cgtttttaaa cggttacgct tcattccgcg
    25981 aatgaccgga gattcacctt tccagaagta gccatgatgc acaatgaccg catccgctcc
    26041 cagacgcacc gcttcatcga gcaaagcctg gctggcggtg acaccggtaa caattttttg
    26101 caccgtctct ttgccttcca cctgcaaacc attcggcgcg taatcactaa tcgccgcgct
    26161 gttcagtttt tcgttaatca gttgttccag ttcggtgttt ttcatcttcg cgccttccgt
    26221 attctgatag ctacaccgtt aacatagcgt tacctcgcct gttcgtcgat agccaatctt
    26281 ttgacatatt aagaaacaaa cccgacgcca aaagacgcaa attgtttata tcatcacgct
    26341 tcagctaatg tatatttatg caatcagaca gcatattgca taaataatca gatctgtatc
    26401 aaagttttaa ctttaaggaa acacaagcac gccgcgcaac tattacgtga cgttgcagtc
    26461 aattgtggaa ttattatgaa taaacacgca tcacaaccgc gcgctattta ctatgtcgtt
    26521 gcgctgcaaa tctgggaata ttttagcttt tacggcatgc gtgccctgct gatcctctat
    26581 ctcaccaatc aactaaaata tagcgataat cacgcctacg agttatttag cgcctactgt
    26641 tcgctggtat atgtcacgcc aatcctcggt ggctttttgg cggataaagt tctcggcaat
    26701 cgcatggcgg tgatgctggg ggcgttgttg atggcgatcg gtcatgtggt gctgggtgcc
    26761 agtgagatcc atccgtcatt cctctatctg tcactgtcga ttatcgtctg cggctatggt
    26821 ctgtttaaat ccaacgtcag ttgcctgctc ggtgagctgt atgagccaac cgatccacgt
    26881 cgtgatggcg gtttctcgct gatgtatgcg gcgggtaacg tggggtctat tatcgcacct
    26941 atcgcctgtg gtttcgccca ggaagaatac agttgggcga tgggctttgg cctggcggcg
    27001 gtgggtatga tcgcgggtct ggtcattttc ttatgtggca atcgtcattt cactcatacc
    27061 cgcggcgtta acaaaaaagt actgcgtgcg acaaacttcc tcctgcccaa ctggggatgg
    27121 ctgctggttc tgctggtggc aacgcctgcg ctgattaccg tgttgttctg gaaagagtgg
    27181 tcggtatacg ccttgattgt cgccacgatc atcggccttg gcgttctggc aaaaatttat
    27241 cgcaaagcag aaaaccaaaa acagcgtaag gagctggggc tgattgttac cctcaccttc
    27301 ttcagcatgt tgttctgggc attcgcacaa caggggggta gctcgattag cctttatatc
    27361 gaccgcttcg ttaaccgcga tatgtttggt tataccgttc cgactgctat gttccagtcg
    27421 attaatgcct tcgcagttat gctgtgcggt gtgttcctgg cgtgggtggt taaagagagc
    27481 gtcgcaggta atcgtaccgt gcgcatctgg ggaaaatttg ctcttggtct cggcctgatg
    27541 agcgccggat tctgcattct gaccttaagc gcccgctggt ccgcaatgta tggtcattct
    27601 tctctgccac tgatggtgtt aggcctggcg gtgatgggct ttgcggaact gtttatcgac
    27661 ccggttgcta tgtcgcagat tacgcgcatt gaaatccccg gcgtgaccgg cgtattaact
    27721 ggcatttata tgctgctttc cggcgcgatt gcgaactatc tggctggcgt gattgccgat
    27781 cagacatcgc aagcttcgtt tgatgcttcc ggggcgatca actattccat caatgcatat
    27841 attgaagtgt ttgatcaaat tacctggggc gcactggcgt gtgtaggagt ggtgttgatg
    27901 atttggctgt atcaggcgct taagttcaga aaccgcgcgc tggcgctgga gtcttaataa
    27961 gccagcacca tgcctgataa aacgctcgct gcgttttatc agactccttt cctcgcttct
    28021 tcgtacgctg ccagcgttcg cagccttgcc tctttgtgat caactatcgg ttgcggataa
    28081 tccagcgtca cacctgcttt ctgcgcccac ttccacggct catgcaccac tttccctggc
    28141 acatcgcgca gttccggtag ccactggcgg ataaactcgc cttcgcggtc aaatttctcg
    28201 ccctgggttg tcgggttaaa aatacgaaaa tacggcgctg catcggttcc ggttgaagcg
    28261 gcccactgcc agccaccgtt attggctgcc aaatcaccat caatcagctg cgacatgaaa
    28321 tatcgctcac cttcgcgcca gtcgatcaat aaatctttca ccaaaaaact ggctgtaatc
    28381 atccgtagcc ggttatgcat ccagccggtg ctgttaagct gacgcatggc agcatcaaca
    28441 atcgggtatc ccgttttgcc ttcctgccag gcctttaaat gcgcggaatt gctctgccac
    28501 tgcacgcggt cggtccagac aataaacgga cgatgtttac acagcgaggg gtaatacgtt
    28561 atcagatgac ggtaaaactc gcgccagatc agctcattaa gccagatact accggcccca
    28621 ccgtccagcg cctgcggctg ttccgccaac aggcgatgca aacactggcg aggcgataac
    28681 ccgcccgttg ccaggctggc ggacaaacgg ctggtgcctt ctaccgcagg gaaatctcgc
    28741 tgttgctcat actctccggc accgttctgg caaaactggc gtaattgcgc aatcgccgct
    28801 ttctcttcca ccgggaaatg cgcagtatcg aaaggctgac gaggataatt cagcgtaatg
    28861 gatggcgcgg gatctatcga tccgctacta cgtacttttg gcgcagcgac gcactccggc
    28921 atcccttctc gcagccgttt aagccaggcg tttttaaatg gcgtaaagac tttgtacatc
    28981 tcatgattgc cagtcatcac cgcccccggc ggcaggatca cgccgtcgtc aaatccttca
    29041 cacaccacgt tacgcagcgc cctctcagcc tgcacatccc gcgcccgctc attcacctca
    29101 tactgatagt tataaaacag atgggtaaca cgattttccg cgcacacctg tttaactatt
    29161 tcgacgctgg cggcaaagtc atccacttca tgaaacagca aaggaatgcc tttttccgcc
    29221 agcgcgattt gtagcccgtt cagttgtgca ttgataaatt cagcctgacg cggcgacata
    29281 ttatgcgccg cccactggcg tggggtagcg atatacaacg ccagcacgcg cgcagacgaa
    29341 ttgcggcagg cggcagccag cgcgagatta tcgtgctgac gtaaatcctg gcgaaaccag
    29401 accagatggg tagtcataaa actcctgaat ggcgcaagtt aatcacacgc ggccaaagtt
    29461 cgaaataacg ctgccctgaa agccaggcgt caggataaag cgccatatag tgtttgatac
    29521 gcatcagcgg cgcaagaagc ggttgctcgc caccgcgata actgtcgata agcgccgcca
    29581 gctgctggcg ttctgtggaa tcaatatgag ggcgaaaata accctgaacg tgcatcaaaa
    29641 cattggtgtg gtcacgtcgg ttggcggggt gagaaagcaa aacaactacg cgttggcggt
    29701 actggttgta atagtcatcc agattttgcc actggtgaat atcagccacg aacgggccaa
    29761 gtttgcggta ttccggctgg gaatgagcca gaaagacgag tttatagcgg ctgtgataat
    29821 cgagaagcgc cccgcgcgtt agtcctcgat ctttgagatt gtgtaactca tgcaaagcaa
    29881 aaatgcggat aagggtgctg tcatcaaaaa gttgttgatt cattactgct cctgaacggt
    29941 ttacaggagt aagtgtagac gccgaaaaaa gaaaaccgcc agcgtttccg ctggcggttt
    30001 tcaatgtatt cagaactcag caatcagtaa aaatcaccag ttgccttttc ggcctgatcc
    30061 atccacaccg gtttctcgct ggttttcgac cagacgcggt gcaggtagct gtaaaagcgg
    30121 gcgcggtctt tccagaaaag catgaaaggc agcgccagaa cgcccgctgc aaccgcacaa
    30181 gtacggcgta aaaagataag ccatgcagga tattctttgt agagttccat acttttctcc
    30241 cccttttgta tctacccggt gaatagcacc ggaaaaatga attcgtttat ctgatgaaaa
    30301 tagtaccgct gtttgtgtaa ttttactact catccgacca cttatttttg cttattgatg
    30361 gtttatttac attcactgtg taattaagtt acataaaagt taaattaata ctaaacatta
    30421 gttaaatcat ggcttttgcc atttttatac tttttttaca ccccgcccgc agatttttgc
    30481 gaaatctttg cagccagaac tctacccttc cggtatcact tttaggccac tggaggtgca
    30541 ctgtgagtgc aggcgtgata gccggcgtgt tgctggtgtt tttattactg ggttatctgg
    30601 tttatgccct gatcaatgcg gaggcgttct gatggctgcg caagggttct tactgattgc
    30661 cacgttttta ctggtattaa tggtgctggc gcgtccctta ggtagcgggc tggcgcggct
    30721 gattaatgat atacctcttc ctggtacgac gggcgttgaa cgcgtactct ttagcgcgct
    30781 tggcgtctct gaccgcgaga tgaactggaa gcagtatctc tcagccattc ttggcctgaa
    30841 tatactgggg ctggcggtgc tgttttttat gttgctcggt cagcactatc tgccgcttaa
    30901 tccacagcag ttgccggggc tgtcgtggga tctggcgctc aataccgccg tcagctttgt
    30961 cacgaacacc aactggcaat cttatagcgg tgaaaccacg ttgagctatt tcagccagat
    31021 ggcgggctta acggtgcaaa actttctttc tgccgccagc gggattgcgg tgatttttgc
    31081 cctcatccgt gcgtttaccc gccagagcat gagcacactc gggaatgcct gggtcgatct
    31141 gctacgcatc acgttatggg tgctagtccc tgtggcgttg ttgatcgcac tgttttttat
    31201 tcaacaaggt gcgctgcaaa actttcagcc ctatcaggcg gtgaataccg ttgaaggagc
    31261 gaaacagctg ttaccaatgg gtccggtggc ttctcaggaa gcgataaaga tgctcggcac
    31321 taacggcggt ggcttcttta atgccaactc gtcgcatccg tttgaaaacc caaccgcact
    31381 gaccaacttc gtgcagatgc tggcgatctt cttgatccca acggcactgt gctttgcctt
    31441 tggcgaagtg gcgggcgatc gccgtcaggg gcgcatgttg ctgtgggcga tgtcagtgat
    31501 ttttatcatc tgcacaggcg tggtgatgtg ggcagaagtt cagggtaatc cgcatctgct
    31561 ggcactgggc gcggacagca gcatcaatat agaaggtaaa gagagtcgtt tcggcgtgct
    31621 ggtcagtagc ctgtttgcgg tcgtgactac ggcggcttcc tgtggcgcgg tgattgcgat
    31681 gcatgattcg tttaccgctc ttggtggcat ggtgccgatg tggttgatgc aaattggtga
    31741 agtggtattc ggcggcgtcg gttccggcct ttacggcatg atgctgtttg tcctgctggc
    31801 ggtgtttatt gccgggctga tgattggtcg tacaccggaa tatctgggta aaaaaatcga
    31861 cgtacgcgag atgaaactga ccgcactggc gattctggtt actccaacac tggtgctgat
    31921 gggcgcggcg ttggcgatga tgaccgacgc cggacgtagc gccatgctca accctggccc
    31981 gcatggtttt agcgaagtgc tgtacgccgt gtcgtccgcc gctaacaaca acggcagcgc
    32041 ctttgccgga ttaagcgcca actctccatt ctggaactgt ttactggcgt tgtgcatgtt
    32101 tgtcgggcgc ttcggggtga ttatcccggt gatggcaatt gccggttcgc tggtgagtaa
    32161 aaagagccaa cccgccagct ccggcacatt gccaacgcac ggcccgctgt ttgttggcct
    32221 gttaatcggc accgtgttgc tggttggcgc actgaccttt atccctgccc tggcgcttgg
    32281 tccggtggcg gaatatctct cctgatgata ttgagtgagc actgaatatg agtcgtaaac
    32341 aactggcgct attcgaacca acacttgtcg ttcaggcgct gaaagaagcg gtgaaaaaat
    32401 taaacccgca ggcgcaatgg cgcaatccgg tgatgtttat cgtctggatc ggcagtctgt
    32461 taaccacctt tatttgcatc gcaatggcaa gcggtgcgat gcctggcaat gcgctgttta
    32521 gcgcggcaat tagcggctgg ctgtgggtca ccgtactgtt cgctaatttc gccgaggcgc
    32581 tggcagaagg ccgcagtaaa gcgcaggcca acagtctgaa aggggtgaaa aaaactgcct
    32641 ttgcccgcaa gcttcgtgag ccgaaatatg gcgctgcggc ggacaaagtt cctgccgatc
    32701 aactgcgtaa aggcgatatc gtgctggtag aagctggcga tattatcccc tgcgatggtg
    32761 aagtcattga aggcggcgca tcggtcgatg aaagcgccat caccggggaa tcggcaccgg
    32821 tgatccgtga atccggcggc gattttgcct ccgtcactgg cggcacgcgt attctttctg
    32881 actggctggt gattgagtgc agcgttaacc ccggcgagac atttctggat aggatgatcg
    32941 cgatggtgga aggcgcacag cgacgcaaaa cgccgaacga gattgccctg accattctcc
    33001 tgattgccct gactatcgtc tttttactgg caaccgccac gctatggccg ttttccgcgt
    33061 ggggcggtaa tgcagtgagt gtaacggtac tggtggcgct gctggtctgt ctgatcccaa
    33121 ccactattgg cggcctgttg tcagcgattg gcgtcgccgg gatgagtcgg atgctgggcg
    33181 cgaatgtgat tgccaccagc ggacgtgcag ttgaagcggc aggtgacgtt gacgttctgc
    33241 tactggataa aaccggcacc atcacacttg gtaaccgtca ggcgtcggag tttatccctg
    33301 cgcagggcgt ggatgaaaaa acgctggctg acgccgcaca actggcttcg ctggctgatg
    33361 aaacgccgga aggccgcagt attgtgatcc tcgccaagca gcgttttaac ctgcgtgagc
    33421 gcgatgtgca gtcgcttcac gccacctttg taccgtttac tgcgcaaagc cggatgagcg
    33481 ggatcaacat cgacaaccgc atgatccgta aaggttctgt cgatgccatt cgccgccatg
    33541 ttgaggctaa cggtggtcac ttccctgccg atgttgatca aaaagtcgat caggttgcgc
    33601 gtcagggagc tacgccgctg gtggtggtgg aaggttctca tgtgctgggc gttattgcgc
    33661 tgaaagatat cgtcaaaggc ggtattaaag agcgcttcgc ccaactgcgc aaaatgggca
    33721 ttaaaacggt gatgattacg ggtgataacc gtctgactgc cgccgcgata gctgcggaag
    33781 cgggtgtcga tgattttctc gccgaagcga caccggaggc caagctggca ttgattcgtc
    33841 agtatcaggc ggaaggccgt ttggtggcga tgaccggcga cggcaccaat gatgctccgg
    33901 cgctggcgca ggcagatgtc gcggtggcga tgaactctgg tactcaggcg gcgaaagaag
    33961 cgggcaatat ggtggatctc gactctaacc cgaccaagtt gatcgaggtg gtacatattg
    34021 gcaaacagat gctgatgacc cgtggctcgc tgaccacctt cagcattgcc aacgatgtgg
    34081 cgaaatactt cgccattatt ccggcggcgt tcgcggcaac gtatccgcag ttaaatgcgc
    34141 tgaacatcat gcgcctgcat tcgcccgact ccgccattct cagtgcggtg attttcaacg
    34201 ccttgattat cgtctttttg attcccctgg cgttaaaagg cgtgagttat aaaccgctta
    34261 ccgcttctgc catgttgcgc cgtaacttat ggatttacgg tctgggtggg ctgctggtgc
    34321 cgtttattgg tatcaaagtc attgatttac tgctaaccgt ttgcggtctg gtgtgaggtt
    34381 taccatgagt ggattacgtc cggcattatc gacatttctc tttctgttat tgattactgg
    34441 cggcgtttac ccgctgctga ccaccgcact ggggcaatgg tggtttccct ggcaggccaa
    34501 cggttcattg attcgtgaag gtgatacggt gcgcggttcg gcattaatcg ggcaaaattt
    34561 taccggcaac ggctattttc atggtcgccc gtcggcaaca gcagaaatgc cctataatcc
    34621 acaggcttct ggcgggagca atctggcagt cagtaacccg gagctggata aacagatagc
    34681 cgcacgcgtt gccgcattac gggccgctaa cccggacgcc agcacgagcg ttccggttga
    34741 actggtgacg gcgtcggcaa gcgggctgga caataacatc accccgcaag cggcggcctg
    34801 gcagatccca cgcgtggcga aagcgcgtaa tctcagcgtt gaacagctca cgcaactgat
    34861 cgcaaaatac agccaacaac cgctggtgaa ctatatcggc cagccggtcg tcaacattgt
    34921 cgaactcaat ctggcactgg ataagcttga tgaataacga acccttacgt cccgaccccg
    34981 atcgtctgct ggaacaagct gccgcgccgc atcgggggaa gctgaaagta ttcttcggtg
    35041 cctgcgcagg cgtcgggaag acctgggcga tgctggcgga agcccagcga ctgcgggcgc
    35101 aagggctgga tattgtggtt ggcgtggtag aaacccacgg tcggaaagat accgccgcca
    35161 tgctgaaagg tctggctgtt ctgccgttaa aacgccaggc gtaccgtggg cggcacatca
    35221 gcgagtttga tctcgatgcc gccctcgccc gccgtccggc actgatctta atggacgaac
    35281 tggcgcacag taatgcgcca ggttcacgtc atcctaaacg ctggcaggac atcgaagagc
    35341 tgctggaagc tggcattgat gttttcacta ccgtcaacgt tcagcatctg gaaagtctga
    35401 atgatgtggt cagcggcgtc accggaattc aggtacggga gaccgtgccc gatccttttt
    35461 ttgatgccgc cgacgacgta gtactggtgg acttgccccc ggacgatctg cgccagcggc
    35521 tgaaagaagg caaagtctat attgccgggc aggcggagcg cgccattgaa cattttttcc
    35581 gcaaaggcaa tctgatcgcc ctgcgcgaac tggcactgcg ccgtactgcc gatcgcgttg
    35641 atgagcaaat gcgcgcctgg cgggggcatc ctggcgaaga gaaagtctgg cacacacgcg
    35701 acgcgatcct tttatgcatc gggcataaca ccggcagtga gaaactggtc cgcgcggcgg
    35761 cgcggttggc ctcgcgcctg ggtagtgtct ggcacgcggt gtatgttgaa acccctgccc
    35821 tgcatcgctt accggagaaa aaacgtcggg caattctcag cgccttacgt ctggcgcagg
    35881 agctgggcgc ggagacggca acactttctg atccagcgga agagaaagcg gtagtgcgtt
    35941 atgcccgtga acataatctc ggcaagatta ttctcggtcg cccggcctcg cgccgctggt
    36001 ggcgtcggga aacgtttgct gaccgactgg cgcgaatcgc ccccgatctc gatcaggtgc
    36061 tggtcgcgct tgatgaacca cccgcccgca cgattaacaa cgcgccggat agccgctctt
    36121 ttaaagacaa gtggcgggta cagattcagg gatgcgtggt tgccgccgcg ttatgcgccg
    36181 ttatcacctt aattgccatg cagtggctga tggcgtttga tgccgccaac ctggtgatgc
    36241 tgtatctgct tggcgtcgtg gtggtggcac tattttacgg acgctggcct tcggtggttg
    36301 ccaccgtcat taatgtggtg agtttcgatc tcttttttat cgccccacgc ggcacgctcg
    36361 ccgtctctga tgtgcaatat ctgctgacct tcgcggtgat gttaaccgtc gggctggtga
    36421 tcgggaacct tactgctggc gtgcgttatc aggcgcgggt agcccgttac cgcgaacaac
    36481 gcacacggca cttatatgaa atgtccaaag ctctggctgt gggccgtagt tcgcaggata
    36541 tcgccgccac cagcgaacag tttattgcct ccacgtttca tgcccgtagc caggtgttgc
    36601 tgcctgatga caacggtaaa ttgcagccgt taacacatcc gcaaggaatg acgccgtggg
    36661 acgatgccat cgcgcagtgg agttttgata aaggcctgcc tgcgggcgcg ggcaccgaca
    36721 cgttacccgg tgtaccgtac cagattttgc cgctaaaaag cggcgagaaa acctacgggc
    36781 tggtggtggt ggaaccgggg aatctgcgcc agttgatgat cccggaacag caacgcctgc
    36841 tggagacgtt tacgctgtta gtcgccaatg cgcttgagcg gctgacactg accgccagcg
    36901 aagaacaggc gcggatggca agcgaacgtg aacagatccg caacgccctg ctggcggcac
    36961 tttcgcatga tttacgcacg ccgcttacgg tgctgttcgg tcaggccgaa atcttaacgc
    37021 tcgatctggc aagcgaagga tcgccccacg cccgccaggc cagcgagatt cgccagcatg
    37081 tgctgaacac gacccgactg gtgaataatc tactggatat ggcgcgaatt cagtccggcg
    37141 gctttaattt gaagaaagag tggttaacgc tggaagaagt ggtcggcagc gcgctgcaaa
    37201 tgctggaacc gggattatca tcgcccatca acctgtcttt gccagaaccg ctgaccttaa
    37261 tccacgttga tgggccactc tttgaacggg tgctgattaa tctgctggaa aacgcggtga
    37321 aatacgcggg tgcgcaggcc gaaattggta tcgatgccca cgttgagggc gaaaatctac
    37381 aactggatgt ctgggataac ggccccggtc ttccgccagg ccaggagcag acgatattcg
    37441 ataagtttgc ccgcgggaat aaagagtcgg cagtgccggg cgtcgggctt gggctggcaa
    37501 tttgtcgggc gattgtggat gtacacggcg gcaccattac cgcgttcaac cgaccggaag
    37561 gcggtgcctg ttttcgtgtt acacttcccc agcaaaccgc tcctgaactt gaagaatttc
    37621 atgaggatat gtgacaaacg ttctgattgt tgaagatgaa caagctattc gtcgctttct
    37681 gcgcacagcg ctggagggcg acggtatgcg cgtctttgaa gccgaaacgc tacaacgggg
    37741 cttgctggaa gcggcaaccc gtaaaccaga tttgattatt ctcgatctcg gcctgcccga
    37801 tggcgatggg attgagttta tccgcgacct gcgccagtgg agcgcggtgc ccgtaattgt
    37861 gctttccgca cgtagcgaag agagcgacaa aatcgccgcg ctggatgccg gagcggatga
    37921 ttacctgagt aagccatttg gtattggcga attgcaggcc cgtctgcgcg tcgctttacg
    37981 ccgccactcc gccaccaccg cgcccgatcc gctggtgaaa ttttccgatg tgaccgtcga
    38041 tttagccgcc cgcgtgatcc atcgcggtga ggaagaggtg catctcaccc cgattgagtt
    38101 tcgcctgctg gcggtgctgc tcaacaatgc cggaaaagtg ctcacccagc gccagctcct
    38161 taaccaggtg tgggggccaa acgcggtcga acacagc
//
LOCUS       DADXDL010000041        37571 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.041, whole genome shotgun sequence.
ACCESSION   DADXDL010000041 DADXDL010000000
VERSION     DADXDL010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37571)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37571)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37571
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.041"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(117..842)
                     /gene="phoU"
                     /locus_tag="IRB70_002400"
     CDS             complement(117..842)
                     /gene="phoU"
                     /locus_tag="IRB70_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBC0632305.1"
                     /translation="MDSLNLNKHISGQFNAELESIRTQVMTMGGMVEQQLSDAITAMH
                     NQDSDLAKRVIEGDKNVNMMEVAIDEACVRIIAKRQPTASDLRLVMVISKTIAELERI
                     GDVADKICRTALEKFSQQHQPLLVSLESLGRHTIQMLHDVLDAFARMDIDEAVRIYRE
                     DKKVDQEYEGIVRQLMTYMMEDSRTIPSVLTALFCARSIERIGDRCQNICEFIFYYVK
                     GQDFRHVGGDELDKLLAGKDPKE"
     gene            complement(857..1630)
                     /gene="pstB"
                     /locus_tag="IRB70_002401"
     CDS             complement(857..1630)
                     /gene="pstB"
                     /locus_tag="IRB70_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000063125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein
                     PstB"
                     /protein_id="HBC0632306.1"
                     /translation="MSMVETAPSKIQVRNLNFYYGKFHALKNINLDIAKNQVTAFIGP
                     SGCGKSTLLRTFNKMFELYPEQRAEGEILLDGDNILTNSQDIALLRAKVGMVFQKPTP
                     FPMSIYDNIAFGVRLFEKLSRADMDERVQWALTKAALWNETKDKLHQSGYSLSGGQQQ
                     RLCIARGIAIRPEVLLLDEPCSALDPISTGRIEELITELKQDYTVVIVTHNMQQAARC
                     SDHTAFMYLGELIEFSNTDDLFTKPAKKQTEDYITGRYG"
     gene            complement(1721..2611)
                     /gene="pstA"
                     /locus_tag="IRB70_002402"
     CDS             complement(1721..2611)
                     /gene="pstA"
                     /locus_tag="IRB70_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBC0632307.1"
                     /translation="MAMVEMQTTAALAESRRKMQARRRLKNRIALTLSMATMAFGLFW
                     LIWILMSTITRGIDGMSLALFTEMTPPPNTEGGGMANALAGSGLLILWATVFGTPLGI
                     MAGIYLAEYGRKSWLAEVIRFINDILLSAPSIVVGLFVYTIVVAQMEHFSGWAGVIAL
                     ALLQVPIVIRTTENMLKLVPDSLREAAYALGTPKWKMIAAITLKASVSGIMTGILLAI
                     ARIAGETAPLLFTALSNQFWSTDMMQPIANLPVTIFKFAMSPFAEWQQLAWAGVLIIT
                     LCVLLLNILARVVFAKNKHG"
     gene            complement(2611..3570)
                     /gene="pstC"
                     /locus_tag="IRB70_002403"
     CDS             complement(2611..3570)
                     /gene="pstC"
                     /locus_tag="IRB70_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008806729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstC"
                     /protein_id="HBC0632308.1"
                     /translation="MAATKPAFNPPGKKGDIIFSVLVKLAALIVLLMLGGIIVSLIIS
                     SWPSIQKFGLAFLWTKEWDAPNDIYGALVPIYGTLVTSFIALLIAVPVSFGIALFLTE
                     LAPGWLKRPLGIAIELLAAIPSIVYGMWGLFIFAPLFAVYFQEPVGNIMSNIPIVGAL
                     FSGPAFGIGILAAGVILAIMIIPYIAAVMRDVFEQTPVMMKESAYGIGCTTWEVIWRI
                     VLPFTKNGVIGGIMLGLGRALGETMAVTFIIGNTYQLDSASLYMPGNSITSALANEFA
                     EAESGLHVAALMELGLILFVITFIVLAASKFMIMRLAKNEGAR"
     gene            complement(3656..4696)
                     /gene="pstS"
                     /locus_tag="IRB70_002404"
     CDS             complement(3656..4696)
                     /gene="pstS"
                     /locus_tag="IRB70_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBC0632309.1"
                     /translation="MKVMRTTVATVVAATLSMSAFSVFAEASLTGAGATFPAPVYAKW
                     ADTYQKETGNKVNYQGIGSSGGVKQIIANTVDFGASDAPLSDEKLAQEGLFQFPTVIG
                     GVVLAVNIPGLKSGELVLDGKTLGDIYLGKIKKWDDEAIAKLNPGLKLPSQNIAVVRR
                     ADGSGTSFVFTSYLAKVNEEWKNNVGTGSTVKWPIGLGGKGNDGIAAFVQRLPGAIGY
                     VEYAYAKQNNLAYTKLISADGKPVSPTEENFANAAKGADWSKTFAQDLTNQKGEDAWP
                     ITSTTFILIHKDQKKPEQGVEVLKFFDWAYKTGAKQANDLDYASLPDSVVEQVRAAWK
                     TNIKDSSGKPLY"
     gene            complement(4944..6014)
                     /locus_tag="IRB70_002405"
     CDS             complement(4944..6014)
                     /locus_tag="IRB70_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001685709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0632310.1"
                     /translation="MNKYIIQWCFTVFIFSFSGATFAAPKGICTSDNGAFHSTLDFSG
                     YLITADENKVGETFNKTVTNGDSYPAHCHCDTGKVGEFPYIYYTARINEALSYAGVRS
                     NVNYFNLNPNLDVGISIDLLGVGYINAPFEYHANRPTGGSYKCSRTDPLSISSGAKAI
                     IYFYIKKTFAGKLIIPETLVAKLYGTISRDTPVDYSQPMADVYIRGDITAPQSCEINS
                     LRPINFDFKEIPAADFSSVAGSTVTTHKITKTVTIECENLGILNTDDISTSFYATEPS
                     TDNSMVVTSNPNVGIKIYDKNNKEINVNGGELPTDMGKSNVFGEKAGSVTFSAAPASL
                     TGARPAPGTFTATATITIEIVR"
     gene            complement(6025..8547)
                     /locus_tag="IRB70_002406"
     CDS             complement(6025..8547)
                     /locus_tag="IRB70_002406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBC0632311.1"
                     /translation="MMTTRIKVGLTAGTCLIFSQSLMAEVSVFNPALLEIDHQSGVDI
                     RQFNRANLMPPGVYSVDIFINGKMFERQDVTFVQDNPDADLHACFVAIKKTLTTFGVK
                     VDALKSLNDVDETVCIDPGPRIEGSSWQFDSDKLQLNISIPQIYMDAMAYDYISPSRW
                     DEGINALTINYDFSGSHTLRSDYGSQETDTSYLNLRNGLNIGPWRLRNYSTLNTTDGS
                     AEYNSISTWIQRDIAALRSQIMIGDTWTASDIFDSTQIRGARLYTDNDMLPASQNGFA
                     PVVRGIAKSNATVIIRQNGYVIYQSAVPQGAFEITDLNTASTGGDLDVTIKEEDGSEQ
                     RFTQPYASLAILKREGQTDVDVSVGELRDEDGFTPDVIQAQILHGFPYGFTLYGGMQA
                     AEKYGSAALGVGKDLGALGAISFDVTHARAKFSHDDTETGQSYRFLYSKRFDDTDTSL
                     RLVGYRYSTEGYYTLNEWASRRNNPEDFWETGNRRSRVEGTLTQSLGRDYGNLYLTLS
                     RQQYWHTDDVERLMQFGYSSSWKRLSWNVSWSYSNTARQGTGNNHASDNTSEQIYMLS
                     LSVPLSGWWGNSYATYSVSQNDNSGSSHQLGLSGTALERNNLSWNLMQSYNSHDDEVG
                     GNMSLTYDGTYGTVNGSYNYSQNSQRLNYGIRGGILAHSEGVTLSQELGETIALVKAP
                     GAAGLEIDNMRGAATDWRGYTVKTQLNPYDENRVAISDNYFSKSNIELDNTVVTMVPT
                     RGAVVKAEFVTRVGYRVLFRVAGTKGKPAPFGAIATVQNTSSADSGIVGDLGELYLSG
                     LPEKGQVMLSWGENAATTCTFDYSLSIPESESGLIEQGVTCH"
     gene            complement(8572..9303)
                     /locus_tag="IRB70_002407"
     CDS             complement(8572..9303)
                     /locus_tag="IRB70_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001572122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial chaperone"
                     /protein_id="HBC0632312.1"
                     /translation="MSRKSCLIRLFKTTVSCKLFTAIILSVFLVQPALTYAGVVIGGT
                     RVVYLSNNPDKSISVFSKEEKIPYLIQAWVDPFNKEDKSKAPFTVIPPVSRLEPAQEK
                     VLRIIHTKGVSLPDDRESVFWLNIKNIPPSASNKAANSLEIAVKTRIKLFWRPASIRL
                     IPEDAAPKVKWHREGRNLIAENPNPIHISVMDVIVDGHDVPLNMIRPFETLTLPLPAN
                     SAGGQMIWRFINDYGAVSDPIKMTL"
     gene            complement(9351..9923)
                     /locus_tag="IRB70_002408"
     CDS             complement(9351..9923)
                     /locus_tag="IRB70_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long polar fimbria major subunit LpfA-O113"
                     /protein_id="HBC0632313.1"
                     /translation="MKRNIIGGAFTLASLMLAGHALAEDGVVHFVGEIVDTTCEVTSD
                     TADQTVPLGKVSKNAFSGVGSLASPQQFSIKLEKCPATYTQAAVRFDGTEAPGGDGDL
                     KVGTPLTAGNPGDFTGTGQAIAATGVGIRIFNQSDNSQVKLYNDSAYTAIDAEGKAEM
                     KFIARYVATNATVTAGTANADSQFTVEYKK"
     gene            complement(10231..12060)
                     /gene="glmS"
                     /locus_tag="IRB70_002409"
     CDS             complement(10231..12060)
                     /gene="glmS"
                     /locus_tag="IRB70_002409"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBC0632314.1"
                     /translation="MCGIVGAIAQRDVAEILLEGLRRLEYRGYDSAGLAVVDAEGHMT
                     RLRRLGKVQMLAQAAEEHPLHGGTGIAHTRWATHGEPSEANAHPHVSEHIVVVHNGII
                     ENHEPLREELKARGYTFVSETDTEVIAHLVNWELKQGGTLREAVLRAIPQLRGAYGTV
                     IMDSRHPDTLLAARSGSPLVIGLGMGENFIASDQLALLPVTRRFIFLEEGDIAEITRR
                     SVNIFDKTGAEVKRQDIESNLQYDAGDKGIYRHYMQKEIYEQPNAIKNTLTGRISHGQ
                     VDLSELGPNADELLSKVEHIQILACGTSYNSGMVSRYWFESLAGIPCDVEIASEFRYR
                     KSAVRRNSLMITLSQSGETADTLAGLRLSKDLGYLGSLAICNVPGSSLVRESDLALMT
                     NAGTEIGVASTKAFTTQLTVLLMLVAKLSRLKGLDASIEHDIVHGLQALPSRIEQMLS
                     QDKRIEALAEDFSDKHHALFLGRGDQYPIALEGALKLKEISYIHAEAYAAGELKHGPL
                     ALIDADMPVIVVAPNNELLEKLKSNIEEVRARGGQLYVFADQDAGFVSSDNMHIIEMP
                     HVEEVIAPIFYTVPLQLLAYHVALIKGTDVDQPRNLAKSVTVE"
     gene            complement(12222..13592)
                     /gene="glmU"
                     /locus_tag="IRB70_002410"
     CDS             complement(12222..13592)
                     /gene="glmU"
                     /locus_tag="IRB70_002410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBC0632315.1"
                     /translation="MLNNAMSVVILAAGKGTRMYSDLPKVLHTLAGKAMVQHVIDAAN
                     ELGAAHVHLVYGHGGDLLKQALKDDNLNWVLQAEQLGTGHAMQQAAPFFADDEDILML
                     YGDVPLISVETLQRLRDAKPQGGIGLLTVKLDDPTGYGRITRENGKVTGIVEHKDATD
                     EQRQIQEINTGILIANGADMKRWLAKLTNNNAQGEYYITDIIALAYQEGREIVAVHPQ
                     RLSEVEGVNNRLQLSRLERVYQFEQAEKLLLAGVMLRDPARFDLRGTLTHGRDVEIDT
                     NVIIEGNVTLGHRVKIGTGCVIKNSVIGDDCEISPYTVVEDANLAAACTIGPFARLRP
                     GAELLEGAHVGNFVEMKKARLGKGSKAGHLTYLGDAEIGDNVNIGAGTITCNYDGANK
                     FKTIIGDDVFVGSDTQLVAPVTVGKGATIAAGTTVTRNVGENALAISRVPQTQKEGWR
                     RPVKKK"
     gene            complement(13941..14360)
                     /gene="atpC"
                     /locus_tag="IRB70_002411"
     CDS             complement(13941..14360)
                     /gene="atpC"
                     /locus_tag="IRB70_002411"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001251972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBC0632316.1"
                     /translation="MAMTYHLDVVSAEQQMFSGLVEKIQVTGSEGELGIYPGHAPLLT
                     AIKPGMIRIVKQHGHEEFIYLSGGILEVQPGNVTVLADTAIRGQDLDEARAMEAKRKA
                     EEHISSSHGDVDYAQASAELAKAIAQLRVIELTKKAM"
     gene            complement(14381..15763)
                     /gene="atpD"
                     /locus_tag="IRB70_002412"
     CDS             complement(14381..15763)
                     /gene="atpD"
                     /locus_tag="IRB70_002412"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017800291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBC0632317.1"
                     /translation="MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNERLVLEVQ
                     QQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEI
                     GEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
                     MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRL
                     RVALTGLTMAEKFRDEGRDVLLFVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEM
                     GVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVVLSRQIASLGIYPA
                     VDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVA
                     RARKIQRFLSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSI
                     EEAVEKAKKL"
     gene            complement(15790..16653)
                     /gene="atpG"
                     /locus_tag="IRB70_002413"
     CDS             complement(15790..16653)
                     /gene="atpG"
                     /locus_tag="IRB70_002413"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBC0632318.1"
                     /translation="MAGAKEIRSKIASVQNTQKITKAMEMVAASKMRKSQDRMAASRP
                     YAETMRKVIGHLAHGNLEYKHPYLEDRDVKRVGYLVVSTDRGLCGGLNINLFKKLLAE
                     MKTWTDKGVQCDLAMIGSKGVSFFNSVGGNVVAQVTGMGDNPSLSELIGPVKVMLQAY
                     DEGRLDKLYIVSNKFINTMSQVPTISQLLPLPASDDDDLKHKSWDYLYEPDPKALLDT
                     LLRRYVESQVYQGVVENLASEQAARMVAMKAATDNGGSLIKELQLVYNKARQASITQE
                     LTEIVSGAAAV"
     gene            complement(16704..18245)
                     /gene="atpA"
                     /locus_tag="IRB70_002414"
     CDS             complement(16704..18245)
                     /gene="atpA"
                     /locus_tag="IRB70_002414"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBC0632319.1"
                     /translation="MQLNSTEISELIKQRIAQFNVVSEAHNEGTIVSVSDGVIRIHGL
                     ADCMQGEMISLPGNRYAIALNLERDSVGAVVMGPYADLAEGMKVKCTGRILEVPVGRG
                     LLGRVVNTLGAPIDGKGPLDHDGFSAVEAIAPGVIERQSVDQPVQTGYKAVDSMIPIG
                     RGQRELIIGDRQTGKTALAIDAIINQRDSGIKCIYVAIGQKASTISNVVRKLEEHGAL
                     ANTIVVVATASESAALQYLAPYAGCAMGEYFRDRGEDALIIYDDLSKQAVAYRQISLL
                     LRRPPGREAFPGDVFYLHSRLLERAARVNAEYVEAFTKGEVKGKTGSLTALPIIETQA
                     GDVSAFVPTNVISITDGQIFLETNLFNAGIRPAVNPGISVSRVGGAAQTKIMKKLSGG
                     IRTALAQYRELAAFSQFASDLDDATRKQLDHGQKVTELLKQKQYAPMSVAQQSLVLFA
                     AERGYLADVELSKIGSFEAALLAYVDRDHAPLMQEINQTGGYNDEIEGKLKGILDSFK
                     ATQSW"
     gene            complement(18258..18791)
                     /gene="atpH"
                     /locus_tag="IRB70_002415"
     CDS             complement(18258..18791)
                     /gene="atpH"
                     /locus_tag="IRB70_002415"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBC0632320.1"
                     /translation="MSEFITVARPYAKAAFDFAVEHQSVERWQDMLAFAAEVTKNEQM
                     AELLSGALAPETLAESFIAVCGEQLDENGQNLIRVMAENGRLNALPDVLEQFIHLRAV
                     SEATAEVDVISAAALSEQQLAKISAAMEKRLSRKVKLNCKIDKSVMAGVIIRAGDMVI
                     DGSVRGRLERLADVLQS"
     gene            complement(18806..19276)
                     /gene="atpF"
                     /locus_tag="IRB70_002416"
     CDS             complement(18806..19276)
                     /gene="atpF"
                     /locus_tag="IRB70_002416"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBC0632321.1"
                     /translation="MNLNATILGQAIAFVLFVLFCMKYVWPPLMAAIEKRQKEIADGL
                     ASAERAHKDLDLAKASATDQLKKAKAEAQVIIEQANKRRSQILDEAKAEAEQERTKIV
                     AQAQAEIEAERKRAREELRKQVAILAVAGAEKIIERSVDEAANSDIVDKLVAEL"
     gene            complement(19338..19577)
                     /gene="atpE"
                     /locus_tag="IRB70_002417"
     CDS             complement(19338..19577)
                     /gene="atpE"
                     /locus_tag="IRB70_002417"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004246596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit C"
                     /protein_id="HBC0632322.1"
                     /translation="MENLNMDLLYMAAAVMMGLAAIGAAIGIGILGGKFLEGAARQPD
                     LIPLLRTQFFIVMGLVDAIPMIAVGLGLYVMFAVA"
     gene            complement(19624..20439)
                     /gene="atpB"
                     /locus_tag="IRB70_002418"
     CDS             complement(19624..20439)
                     /gene="atpB"
                     /locus_tag="IRB70_002418"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBC0632323.1"
                     /translation="MASENMTPQDYIGHHLNNLQLDLRTFSLVDPHNPPATFWTINID
                     SMFFSVVLGLLFLVLFRSVAKKATSGVPGKFQTAIELVIGFVNGSVKDMYHGKSKLIA
                     PLALTIFVWVFLMNLMDLLPIDLLPYIAEHVLGLPALRVVPSADVNVTLSMALGVFIL
                     ILFYSIKMKGIGGFTKELTLQPFNHWAFIPVNLILEGVSLLSKPVSLGLRLFGNMYAG
                     ELIFILIAGLLPWWSQWILNVPWAIFHILIITLQAFIFMVLTIVYLSMASEEH"
     gene            complement(20448..20828)
                     /gene="atpI"
                     /locus_tag="IRB70_002419"
     CDS             complement(20448..20828)
                     /gene="atpI"
                     /locus_tag="IRB70_002419"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418195.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit I"
                     /protein_id="HBC0632324.1"
                     /translation="MSVSLVSRNVARKLLLVQLLVVIASGLLFSLKDPFWGVSAISGG
                     LAVFLPNVLFMIFAWRHQAHTPAKGRVAWTFAFGEAFKVLAMLVLLVVALAVLKAVFL
                     PLIVTWVLVLVVQILAPAVINNKG"
     gene            complement(21445..22068)
                     /gene="rsmG"
                     /locus_tag="IRB70_002420"
     CDS             complement(21445..22068)
                     /gene="rsmG"
                     /locus_tag="IRB70_002420"
                     /EC_number="2.1.1.170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBC0632325.1"
                     /translation="MLNKLSLLLKDAGISLTDHQKNQLIAYVNMLHKWNKAYNLTSVR
                     DPNEMLVRHILDSIVVAPYLQGERFIDVGTGPGLPGIPLSIVRPEAHFTLLDSLGKRV
                     RFLRQVQHELKLENIEPVQSRVEEFPSEPPFDGVISRAFASLNDMVSWCHHLPGEQGR
                     FYALKGQMPEDEIALLPEEYQVESVVKLQVPALDGERHLVVIKANKI"
     gene            complement(22132..24021)
                     /gene="mnmG"
                     /locus_tag="IRB70_002421"
     CDS             complement(22132..24021)
                     /gene="mnmG"
                     /locus_tag="IRB70_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBC0632326.1"
                     /translation="MFYPDPFDVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTLGQ
                     MSCNPAIGGIGKGHLVKEVDALGGLMAKAIDQAGIQFRILNASKGPAVRATRAQADRV
                     LYRQAVRTALENQPNLMIFQQAVEDLIVENDRVVGAITQMGLKFRAKAVVLTVGTFLD
                     GKIHIGLDNYSGGRAGDPPSIPLSRRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQ
                     HGDNPMPVFSFMGNASQHPQQVPCYITHTNEKTHDVIRSNLDRSPMYAGVIEGVGPRY
                     CPSIEDKVMRFADRNQHQIFLEPEGLTSNEIYPNGISTSLPFDVQMQIVRSMQGMENA
                     KIVRPGYAIEYDFFDPRDLKPTLESKFIQGLFFAGQINGTTGYEEAAAQGLLAGLNAA
                     RLSADKEGWAPARSQAYLGVLVDDLCTLGTKEPYRMFTSRAEYRLMLREDNADLRLTE
                     IGRELGLVDDERWARFNEKLENIERERQRLKSTWVTPSAEAAAEVNAHLTAPLSREAS
                     GEDLLRRPEMTYEKLTTLTPFAPALTDEQAAEQVEIQVKYEGYIARQQDEIEKQLRNE
                     NTLLPATLDYRQVSGLSNEVIAKLNDHKPASIGQASRISGVTPAAISILLVWLKKQGM
                     LRRSA"
     gene            complement(24400..24843)
                     /gene="mioC"
                     /locus_tag="IRB70_002422"
     CDS             complement(24400..24843)
                     /gene="mioC"
                     /locus_tag="IRB70_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein MioC"
                     /protein_id="HBC0632327.1"
                     /translation="MADITLISGSTLGGAEYVAEHLAEKLEEAGFTTETLHGPLLEDL
                     SASGIWLIISSTHGAGDIPDNLSPFYEALQEQKPDLSAVRFGAIGIGSREYDTFCGAI
                     DKLEAELKNSDAKQTGETLKINILDHDIPEDPAEEWLGSWINLLK"
     gene            complement(24933..25391)
                     /gene="asnC"
                     /locus_tag="IRB70_002423"
     CDS             complement(24933..25391)
                     /gene="asnC"
                     /locus_tag="IRB70_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator AsnC"
                     /protein_id="HBC0632328.1"
                     /translation="MENYLIDNLDRGILEALMGNARTAYAELAKQFGVSPGTIHVRVE
                     KMKQAGIITGARIDVSPKQLGYDVGCFIGIILKSAKDYPSALAKLESLDEVTEAYYTT
                     GHYSIFIKVMCRSIDALQHVLINKIQTIDEIQSTETLIVLQNPIMRTIKP"
     gene            25543..26535
                     /gene="asnA"
                     /locus_tag="IRB70_002424"
     CDS             25543..26535
                     /gene="asnA"
                     /locus_tag="IRB70_002424"
                     /EC_number="6.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--ammonia ligase"
                     /protein_id="HBC0632329.1"
                     /translation="MKTAYIAKQRQISFVKSHFSRQLEERLGLIEVQAPILSRVGDGT
                     QDNLSGCEKAVQVKVKALPDAQFEVVHSLAKWKRQTLGQHDFSAGEGLYTHMKALRPD
                     EDRLSPLHSVYVDQWDWERVMGDGERQFSTLKSTVEAIWAGIKATEAAVSEEFGLAPF
                     LPDQIHFVHSQELLSRYPDLDAKGRERAIAKDLGAVFLVGIGGKLSDGHRHDVRAPDY
                     DDWSTPSELGHAGLNGDILVWNPVLEDAFELSSMGIRVDADTLKHQLALTGDEDRLQL
                     EWHQALLRGEMPQTIGGGIGQSRLTMLLLQLPHIGQVQCGVWPAAVRESVPSLL"
     gene            complement(26540..27991)
                     /gene="viaA"
                     /locus_tag="IRB70_002425"
     CDS             complement(26540..27991)
                     /gene="viaA"
                     /locus_tag="IRB70_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA stimulator ViaA"
                     /protein_id="HBC0632330.1"
                     /translation="MLTLDTLNVMLAVSEEGLIEEMIIALLASPQLAVFFEKFPRLKA
                     AITDDVPRWREALRSRLKDARVPPELTEEVMCYQQSQLLSTPQFIVQLPQILDLLHRL
                     NSPWAEQARQLVDANSTITSALHTLFLQRWRLSLIVQATTLNQQLLEEEREQLLSEVQ
                     ERMTLSGQLEPILADNNTAAGRLWDMSAGQLKRGDYQLIVKYGEFLNEQPELKRLAEQ
                     LGRSREAKSIPRNDAQMETFRTMVREPATVPEQVDGLQQSDDILRLLPPELATLGITE
                     LEYEFYRRLVEKQLLTYRLHGESWREKVIERPVVHKDYDEQPRGPFIVCVDTSGSMGG
                     FNEQCAKAFCLALMRIALAENRRCYIMLFSTEIVRYELSGPQGIEQAIRFLSQQFRGG
                     TDLASCFRAIMERLQSREWFDADAVVISDFIAQRLPDDVTSKVKELQRVHQHRFHAVA
                     MSAHGKPGIMRIFDHIWRFDTGMRSRLLRRWRR"
     gene            complement(27985..29481)
                     /gene="ravA"
                     /locus_tag="IRB70_002426"
     CDS             complement(27985..29481)
                     /gene="ravA"
                     /locus_tag="IRB70_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312715.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase RavA"
                     /protein_id="HBC0632331.1"
                     /translation="MAHPHLLAERISRLSSSLEKGLYERSHAIRLCLLAALSGESVFL
                     LGPPGIAKSLIARRLKFAFQNARAFEYLMTRFSTPEEVFGPLSIQALKDEGRYERLTS
                     GYLPEAEIVFLDEIWKAGPAILNTLLTAINERQFRNGAHVEKIPMRLLVAASNELPEA
                     DSSLEALYDRMLIRLWLDKVQDKANFRSMLTSQQDENDNPVPASLQVTDEEYERWQKE
                     IGEITLPDHVFELIFMLRQQLDKLPDAPYVSDRRWKKAIRLLQASAFFSGRSAVAPVD
                     LILLKDCLWYDAQSLNLIQQQIDVLMTGHAWQQQGMLTRLGAIVQRHLQLQQQQSDKT
                     ALTVIRLGGIFSRRQQYQLPVNVTASTLTLLLQKPLKLHDMEVVHISFERNALEQWLS
                     KGGEIRGKLNGIGFAQKLNLEVDSTQHLVVRDVSLQGSTLALPGSSAEGLPGEIKQQL
                     EELESDWRKQHVLFSEQQKCLFISGDWLGRIEASLQDVGAQIRQAQQC"
     gene            29704..31572
                     /gene="kup"
                     /locus_tag="IRB70_002427"
     CDS             29704..31572
                     /gene="kup"
                     /locus_tag="IRB70_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000102304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low affinity potassium transporter Kup"
                     /protein_id="HBC0632332.1"
                     /translation="MSTDNKQSLPAITLAAIGVVYGDIGTSPLYTLRECLSGQFGFGI
                     ERDAVFGFLSLIFWLLIFVVSIKYLTFVMRADNAGEGGILTLMSLAGRNTSARTTSML
                     VIMGLIGGSFFYGEVVITPAISVMSAIEGLEIVAPQLDTWIVPLSIIVLTLLFMIQKH
                     GTAMVGKLFAPIMLTWFLILAGLGLRSIIANPEVLHALNPMWAVHFFLEYKTVSFIAL
                     GAVVLSITGVEALYADMGHFGKFPIRLAWFTVVLPSLTLNYFGQGALLLKNPEAIKNP
                     FFLLAPDWALIPLLIIAALATVIASQAVISGVFSLTRQAVRLGYLSPMRIIHTSEMES
                     GQIYIPFVNWMLYVAVVIVIVSFEHSSNLAAAYGIAVTGTMVLTSILSTTVARQNWHW
                     NKYFVALILIAFLCVDIPLFTANLDKLLSGGWLPLSLGTVMFIVMTTWKSERFRLLRR
                     MHEHGNSLEAMIASLEKSPPVRVPGTAVYMSRAINVIPFALMHNLKHNKVLHERVILL
                     TLRTEDAPYVHNVRRVQIEQLSPTFWRVVASYGWRETPNVEEVFHRCGLEGLSCRMME
                     TSFFMSHESLILGKRPWYLRLRGKLYLLLQRNALRAPDQFEIPPNRVIELGTQVEI"
     gene            31739..32158
                     /gene="rbsD"
                     /locus_tag="IRB70_002428"
     CDS             31739..32158
                     /gene="rbsD"
                     /locus_tag="IRB70_002428"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709562.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBC0632333.1"
                     /translation="MKKGTVLNSDISSVISRLGHTDTLVVCDAGLPIPKSTTRIDMAL
                     TQGVPSFMQVLGVVTNEMQVEAAIIAEEIKQHNPQLHETLLTHLEQLQKHQGNTIEIR
                     YTTHEQFKQQTAESQAVIRSGECSPYANIILCAGVTF"
     gene            32166..33671
                     /gene="rbsA"
                     /locus_tag="IRB70_002429"
     CDS             32166..33671
                     /gene="rbsA"
                     /locus_tag="IRB70_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter ATP-binding protein RbsA"
                     /protein_id="HBC0632334.1"
                     /translation="MEALLQLKGIDKAFPGVKALSGAALNVYPGRVMALVGENGAGKS
                     TMMKVLTGIYTRDAGTLLWLGKETTFTGPKSSQEAGIGIIHQELNLIPQLTIAENIFL
                     GREFVNRFGKIDWKTMYAEADKLLAKLNLRFKSDKLVGDLSIGDQQMVEIAKVLSFES
                     KVIIMDEPTDALTDTETESLFRVIRELKSQGRGIVYISHRMKEIFEICDDVTVFRDGQ
                     FIAEREVASLTEDSLIEMMVGRKLEDQYPHLDKAPGDIRLKVDNLCGPGVNDVSFTLR
                     KGEILGVSGLMGAGRTELMKVLYGALPRTSGYVTLDGHEVVTRSPQDGLANGIVYISE
                     DRKRDGLVLGMSVKENMSLTALRYFSRAGGSLKHADEQQAVSDFIRLFNVKTPSMEQA
                     IGLLSGGNQQKVAIARGLMTRPKVLILDEPTRGVDVGAKKEIYQLINQFKADGLSIIL
                     VSSEMPEVLGMSDRIIVMHEGHLSGEFTREQATQEVLMAAAVGKLNRVNQE"
     gene            33676..34641
                     /gene="rbsC"
                     /locus_tag="IRB70_002430"
     CDS             33676..34641
                     /gene="rbsC"
                     /locus_tag="IRB70_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002882531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter permease"
                     /protein_id="HBC0632335.1"
                     /translation="MTTQTVSGRRYFTKAWLMEQKSLIALLVLIAIVSTLSPNFFTIN
                     NLFNILQQTSVNAIMAVGMTLVILTSGIDLSVGSLLALTGAVAASIVGIEVNALVAVA
                     AALALGAAIGAVTGVIVAKGRIQAFIATLVMMLLLRGVTMVYTNGSPVNTGFTENADL
                     FGWFGIGRPLGVPTPVWIMGIVFLAAWYMLHHTRLGRYIYALGGNEAATRLSGINVNK
                     IKIIVYSLCGLLASLAGIIEVARLSSAQPTAGTGYELDAIAAVVLGGTSLAGGKGRIV
                     GTLIGALILGFLNNGLNLLGVSSYYQMIVKAVVILLAVLVDNKKQ"
     gene            34666..35556
                     /gene="rbsB"
                     /locus_tag="IRB70_002431"
     CDS             34666..35556
                     /gene="rbsB"
                     /locus_tag="IRB70_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose ABC transporter substrate-binding protein
                     RbsB"
                     /protein_id="HBC0632336.1"
                     /translation="MNMKKLATLVSAVALSATVSANAMAKDTIALVVSTLNNPFFVSL
                     KDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVGNAVKM
                     ANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGT
                     SAARERGEGFQQAVAAHKFNVLASQPADFDRTKGLNVMQNLLTAHPDVQAVFAQNDEM
                     ALGALRALQTAGKSDVMVVGFDGTPDGEKAVNDGKLAATIAQLPDQIGAKGVETADKV
                     LKGEKVQAKYPVDLKLVVKQ"
     gene            35682..36611
                     /gene="rbsK"
                     /locus_tag="IRB70_002432"
     CDS             35682..36611
                     /gene="rbsK"
                     /locus_tag="IRB70_002432"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBC0632337.1"
                     /translation="MQNAGSLVVLGSINADHILNLQSFPTPGETVTGNHYQVAFGGKG
                     ANQAVAAGRSGANIAFIACTGDDSIGESVRQQLATDNIDISPVSVIKGESTGVALIFV
                     NGEGENVIGIHAGANAALSPALVEAQRERIANASALLMQLESPLESVMAAAKIAHQNK
                     TIVALNPAPARELPDELLALVDIITPNETEAEKLTGIRVENDEDAAKAAQVLHEKGIR
                     TVLITLGSRGVWASVNGEGQRVPGFRVQAVDTIAAGDTFNGALITALLEEKTLPEAIR
                     FAHAAAAIAVTRKGAQPSVPWREEIDAFLDRQR"
     gene            36615..>37571
                     /gene="rbsR"
                     /locus_tag="IRB70_002433"
     CDS             36615..>37571
                     /gene="rbsR"
                     /locus_tag="IRB70_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose operon transcriptional repressor RbsR"
                     /protein_id="HBC0632338.1"
                     /translation="MATMKDVARLAGVSTSTVSHVINKDRFVSEAITAKVDAAIKELN
                     YAPSALARSLKLNQTHTIGMLITASTNPFYSELVRGVERSCFERGYSLVLCNTEGDEQ
                     RMNRNLETLMQKRVDGLLLLCTETHQPSREIMQRYPTVPTVMMDWAPFDGDSDLIQDN
                     SLLGGDLATQYLIDKGHTRIACITGPLDKTPARLRLEGYRAAMKRAGLNIPDGYEVTG
                     DFEFNGGFDAMRQLLSHPLRPQAVFTGNDAMAVGVYQALYQAELQVPQDIAVIGYDDI
                     ELASFMTPPLTTIHQPKDELGELAIDVLIHRITQPTLQQQRLQ"
BASE COUNT         9143 a         9613 c         9399 g         9416 t
ORIGIN      
        1 cgaggtgagt ttgtgtggca atatttcagg gagaaagttt atcagcccgg taactatgta
       61 tgaccgggct gattgccaga ttcggcgtaa aagccttatc tgacctactg ttagcgttac
      121 tctttcgggt cttttccggc cagcagttta tccagctcat caccgcctac atgacggaaa
      181 tcctgcccct tcacgtagta gaagataaac tcacaaatat tctggcagcg gtcgccgata
      241 cgttcgattg aacgcgcaca gaatagcgcg gtaagtacgc tcggaatggt gcgcgaatct
      301 tccatcatgt aggtcatcag ttgacgaaca ataccttcgt actcctgatc gactttttta
      361 tcttcccgat aaatacgtac cgcttcgtca atgtccatcc gcgcgaacgc gtccagcacg
      421 tcgtgcagca tctggatggt atgacggccc agcgactcca gacttaccag caacggctga
      481 tgctgctggg agaatttctc cagcgcagta cggcagattt tgtccgccac gtcgccaata
      541 cgctccagct cggcaatggt tttactgatc accataacca gacgcaggtc gctcgccgtc
      601 ggctgacgtt tggcgataat gcgcacgcaa gcttcatcga tcgccacttc catcatgttg
      661 acgttcttgt cgccttcgat gacgcgcttc gccagatcgc tgtcctggtt atgcatcgcg
      721 gtgattgcat cagaaagctg ctgctccacc atgccgccca tggtcatcac ctgcgtgcgg
      781 atactttcca gttcggcgtt gaactggccg gaaatatgtt tattaagatt gagactgtcc
      841 ataacgcact cctgaatcaa ccgtaacgac cggtgatgta gtcttctgtt tgtttcttcg
      901 ctggcttggt gaacagatcg tccgtgttgc tgaactcaat caattcgccc aggtacataa
      961 acgccgtgtg gtcggaacaa cgcgcagcct gctgcatgtt gtgggtgacg atcaccacgg
     1021 tataatcctg cttcagttcg gtgatcagct cttcaatacg cccggtggag atggggtcga
     1081 gcgccgaaca cggttcgtcg agcagcagca cttccgggcg aatggcgata ccacgcgcaa
     1141 tgcacagacg ctgttgctga ccaccagaga gagagtaacc gctctggtgc aatttatctt
     1201 tggtttcgtt ccacaatgcg gctttggtca atgcccactg cacgcgctcg tccatgtcgg
     1261 cacgggagag cttctcaaac agacgaacgc caaaggcgat gttgtcgtag atggacatcg
     1321 ggaacggcgt cggtttctgg aacaccatgc ccactttcgc acgcagcagg gcgatatcct
     1381 gagagttggt caggatgttg tcgccatcga gcagaatttc accttccgca cgctgctccg
     1441 ggtacagttc aaacattttg ttgaaggtac gcagcagcgt cgatttaccg cagccggacg
     1501 gcccgataaa cgccgtaacc tggtttttgg cgatatccag gttgatgttt ttcagggcat
     1561 ggaatttgcc gtagtagaag ttcaaattac gaacctgaat tttactcggg gcagtttcaa
     1621 ccatactcat tgcaatcttt tcctcatcgt gcctgatgca cttcgcgaat caggcttacc
     1681 gtaggccgga taaggcgttc acgccgcatc cggcaaagtg ttaaccgtgt ttattcttcg
     1741 caaatacaac gcgcgccaga atgttcagca gcaggacgca cagggtaatg atcaacaccc
     1801 cggcccaggc cagttgctgc cattccgcaa acgggctcat cgcaaactta aagatcgtca
     1861 ccggcaggtt ggcgatcggc tgcatcatgt ccgtgctcca gaactggttg gagagcgcgg
     1921 taaacagcag cggcgcggtt tcaccggcaa tacgggcaat cgccagcagg ataccggtca
     1981 taatcccgga caccgacgct ttcagcgtga tcgcggcgat catcttccac ttcggtgtac
     2041 ccagcgcata agccgcttca cgcaggctgt ctggcaccag tttcagcatg ttctcggtgg
     2101 tgcggataac aatcggcacc tgcaacagcg ccagcgcaat cacgcccgcc cagccggaga
     2161 agtgctccat ctgcgccacc acaatggtgt aaacaaacag cccaaccaca atcgacggtg
     2221 cggagagcag aatgtcgtta atgaagcgaa tcacttctgc cagccaggat ttacgaccat
     2281 attcagccag gtaaatcccc gccataatgc ccagcggcgt accgaatacc gtggcccaca
     2341 aaattaacag cccgctaccc gccagggcgt tcgccatacc accgccttcc gtattgggcg
     2401 gcggcgtcat ttcagtgaac agcgccagcg acataccatc gataccgcga gtgatggtgg
     2461 acattaaaat ccagatcagc cagaacaggc cgaaggccat cgtcgccatt gagagcgtca
     2521 acgcaatacg gtttttgagg cggcgacgcg cctgcatttt acggcgggat tcagccagcg
     2581 ccgcagtggt ttgcatttca accatagcca ttagcgtgcc ccctcattct tagccaggcg
     2641 cataatcata aacttcgatg cggcgaggac gatgaaggta atcacaaaca ggatcaggcc
     2701 cagttccatc agtgcggcaa cgtgcagacc ggattccgct tcagcaaatt cgttcgccag
     2761 cgcagaggtg atactgttgc ccggcatgta cagcgaggcg ctgtcgagct ggtaggtgtt
     2821 accgatgata aaggtcaccg ccatggtttc accgagcgcg cgccccagac ccaacatgat
     2881 gccgccgata accccatttt tggtgaacgg aagaacgata cgccagataa cttcccaggt
     2941 ggtgcagccg ataccgtagg ctgactcttt catcatcacc ggggtttgct cgaatacatc
     3001 gcgcattacc gctgcaatgt acggaataat catgatggcg aggatcacgc ctgccgcgag
     3061 gatgccaata ccaaaggccg ggccggagaa cagcgcgcca acaatcggga tattcgacat
     3121 gatattgccg accggctcct ggaagtaaac ggcgaacagt ggcgcgaaga taaacaggcc
     3181 ccacatgccg taaacgatac ttggaatggc tgccagcagc tcaatggcga tacccagcgg
     3241 gcgcttcagc cagccaggag caagctcggt caggaacagg gcgataccga aactcaccgg
     3301 gacggcgatc agcagcgcga taaacgaggt caccagcgta ccgtagatcg gcaccagcgc
     3361 cccgtagata tcgttcggcg catcccactc tttggtccac aggaaagcca gaccaaattt
     3421 ctgaatgctc ggccaggatg agatgatcag agagacaata atgccaccca acatcaatag
     3481 cacaatcagc gccgccagtt ttaccagcac gctgaaaatt atgtcgccct ttttacccgg
     3541 tgggttaaaa gcaggcttgg ttgcagccat aagttactct tcagttaaac gcgtttacaa
     3601 agtcattttg taatgccgga tgcggcgtaa aacaccgtac ccggcctgaa ttttattagt
     3661 acagcggctt gccgctactg tctttaatat tggtcttcca cgcagcgcga acctgttcca
     3721 ctacgctatc cggcaggctg gcataatcca ggtcgttagc ctgtttagcc ccggttttgt
     3781 acgcccagtc gaagaacttc agcacttcta caccctgctc aggtttcttc tgatctttat
     3841 ggatcagaat gaacgtggta gaagtgatag gccatgcatc ttcgcctttc tggttagtca
     3901 gatcctgagc gaatgttttg ctccagtctg cgccttttgc tgcattagcg aagttttctt
     3961 cggtcggact aaccggttta ccatcagcgg agatcagttt ggtgtacgcc aggttgttct
     4021 gcttcgcgta agcatattca acgtaaccaa ttgcacccgg cagacgctga acgaacgcgg
     4081 cgataccgtc gttaccttta ccgcccagac cgatcggcca ttttacggta gagccagtac
     4141 caacgttgtt tttccactct tcgttcactt tcgccaggta gctggtgaag acgaaggatg
     4201 tcccggagcc atctgcacgg cgcacgacag caatgttctg tgaaggcagt ttcagacccg
     4261 gattcagttt ggcgatggct tcatcatccc actttttgat tttgcccagg tagatgtcgc
     4321 cgagggtttt accatccagc accagttcgc cagacttcag ccctggaatg ttaacagcca
     4381 gcaccacgcc gccaatcacg gtcgggaact ggaacaggcc ttcctgagcc aatttttcat
     4441 cagacagcgg cgcgtcagag gcaccaaaat caacggtatt agcgataatc tgttttacgc
     4501 caccggaaga accgataccc tggtagttaa ctttattacc ggtttctttc tggtaagtgt
     4561 cagcccattt ggcatacacc ggcgcaggga aggttgcacc tgcacctgtc aggcttgctt
     4621 ctgcaaacac agagaaagcg ctcatcgata aggtcgcggc gacaacagtt gcgacggtgg
     4681 tacgcataac tttcataatg tctcctggga ggattcataa agcattgttt gttggctacg
     4741 agaagcaaaa taggacaaac aggtgacagt tatatgtaag gtttatgaca gttttatgac
     4801 aaatcagaat tattaattaa ctttttgatt ttattgacta agaaaaagaa aagtagtgtc
     4861 atctttttgt catgcaaagt gaaaactcgc ggacaaaaat gcgtaagatg acaacggtgt
     4921 gaggaacacc gctgtcagtt cgtttagcgt acaatctcaa ttgttatcgt tgcagtcgcg
     4981 gtaaatgttc ctggcgcggg gcgagccccc gtgaggcttg caggagcagc agaaaaagtg
     5041 acgctaccgg ctttttcacc aaagacgttt gatttaccca tatctgtcgg cagttcacca
     5101 ccgttaacgt tgatttcctt attattttta tcataaattt ttatcccaac gttcgggttt
     5161 gatgtcacga ccattgagtt gtcagtactg ggttcggtag cataaaaaga ggtactgata
     5221 tcatcagtat ttagtattcc taaattttca cactcaatgg tgacggtttt ggtaatttta
     5281 tgcgttgtca cggtacttcc agctaccgaa gaaaaatctg ctgcaggaat ttctttaaaa
     5341 tcaaaattaa tgggtcttaa actgttaatt tcacagcttt gcggtgcagt gatatcgcca
     5401 cgaatataaa catccgccat aggttgtgag taatcaaccg gagtgtcacg gcttatagtt
     5461 ccgtacaatt ttgccacgag agtttcagga ataattaact ttccagcaaa agtcttctta
     5521 atataaaaat aaattattgc ttttgcacca ctggaaatac ttaatgggtc cgtgcgacta
     5581 catttatatg aacctccagt aggcctgtta gcatggtatt caaaaggtgc attaatgtat
     5641 cctacaccga gaaggtctat cgatattcca acatccagat taggattcaa attaaagtag
     5701 tttacattag aacgaacacc cgcataactt aaggcctcgt ttattctcgc tgtatagtaa
     5761 atataaggaa actcccccac tttccctgta tcacaatggc agtgagcagg ataagagtcc
     5821 ccatttgtca cggttttatt aaaggtctct cccactttgt tctcgtctgc cgtaatcaga
     5881 tagccggaaa aatcaagtgt gctatgaaag gccccattat ctgaggtgca gatacctttt
     5941 ggggccgcaa atgttgcacc actaaaggag aagataaaaa cagtaaagca ccactgtata
     6001 atatacttgt tcataaaaat ccttttaatg acatgtcaca ccttgttcaa ttaagccgct
     6061 ttcactttct ggtattgaaa gtgaataatc gaaggtgcat gtagtggcgg cattttcccc
     6121 ccaggagagc atcacttgcc ccttttcagg aaggccagag agataaagct cccccaggtc
     6181 accgacaatc cctgaatcag cggagcttgt attttgtact gtagcaatag cgccaaaagg
     6241 tgctggttta ccttttgtac ccgccaccct gaaaagcaca cgataaccta cacgagtaac
     6301 aaattcggct ttaaccaccg cgccacgggt gggaaccatc gtaacgacgg tattatcaag
     6361 ttctatattc gacttcgaga aatagttatc gctgattgct acccggtttt catcataagg
     6421 gtttagctgt gtcttgaccg tataaccacg ccagtccgtc gcagcaccac gcatattgtc
     6481 tatttctaac ccggcagccc ctggtgcttt aacaagagct atggtttcac ccaactcctg
     6541 gcttaacgtt acgccttcgc tgtgagccag aattccccct ctgataccat aattcagcct
     6601 ctgagaattt tggctgtagt tatagctgcc gttcaccgtg ccataagtgc catcataggt
     6661 cagggacata ttaccgccaa cctcatcatc atggctgtta taggactgca ttaaattcca
     6721 ggaaaggtta tttctttcca gcgccgtacc gctgagtcca agttgatgtg agctaccgga
     6781 attatcgttt tgtgaaacag aataggtggc ataactattc ccccaccagc ccgataaagg
     6841 aacagataaa gagagcatgt agatctgctc actggtgtta tcactggcat ggttgttccc
     6901 cgtcccctgc cgggcagtat tggaataact ccaggagacg ttccacgaga gacgcttcca
     6961 gctactgctg tagccaaatt gcattaatcg ttcaacatca tcggtatgcc agtactgctg
     7021 gcgacttaat gtcagatata agttgccata atctctgccc agtgattgcg ttaacgttcc
     7081 ctccacacgg ctgcggcggt taccggtttc ccagaaatct tcaggattat tacgccggga
     7141 cgcccattca ttgagggtat aataaccttc ggtggagtaa cgatagccaa ccaggcgcaa
     7201 gctggtatcc gtatcgtcaa agcgtttcga gtacaggaag cgataagact gaccggtttc
     7261 cgtatcatca tggctaaatt tcgcgcgagc atgtgtcaca tcgaaagaaa ttgcgcccaa
     7321 tgcgccaaga tctttaccga cacccaaagc ggcagaacca tacttttcag cagcctgcat
     7381 acctccatac aaggtgaaac cgtagggaaa accatgaagg atctgagcct gaataacgtc
     7441 aggggtaaag ccatcttcat cgcgtaattc tcccacactg acatcaacat cagtttgacc
     7501 ttcacgtttg aggatggcta acgacgcata aggttgagta aatcgttgtt cgctaccgtc
     7561 ttcttctttg atggttacgt ccagatcacc acctgtactg gcggtgttga ggtcggtaat
     7621 ttcaaaagca ccttgtggaa cggctgactg ataaatcacg tagccattct ggcgaataat
     7681 gacagtggcg ttagactttg caatcccacg cactacgggg gcaaatccgt tttggctggc
     7741 aggcaacata tcgttatcgg tatacaagcg tgcgccacga atttgcgtac tgtcgaagat
     7801 atcgctcgcc gtccacgtat cacctatcat aatctggctt cttaacgcag ctatatcacg
     7861 ttgtatccag gtgcttatag agttgtattc tgcactgcca tcggtcgtat ttaaggtgct
     7921 gtaattgcgt aatcgccacg gcccaatatt cagtccattg cgcaaattga gataactggt
     7981 atctgtctct tgtgaaccat aatccgaacg tagagtatgt gaaccagaaa aatcgtagtt
     8041 gatggtgagc gcgttaatcc cctcatccca acgcgagggg ctgatgtaat cataagccat
     8101 cgcatccata tagatttggg gaatggagat attcagttgc agtttatcgc tgtcgaactg
     8161 ccatgatgag ccttcaatgc gtggcccagg atcaatacag actgtttcat ctacatcatt
     8221 gagcgatttc agcgcatcaa cttttacgcc aaaggtggtt agcgtttttt taatagcgac
     8281 aaagcaggcg tgtaaatcag catcgggatt atcctgaaca aaggtcacat cctgacgttc
     8341 aaacatttta ccgttgataa aaatatcaac gctataaaca cctgggggca tcaggtttgc
     8401 ccgattaaac tggcgaatat cgactccgga ttgatggtcg atttccagaa gcgccggatt
     8461 gaatacactg acctcggcca tcaggctttg cgagaaaatc agacacgtcc ctgccgtgag
     8521 gccaaccttt attctggtcg tcatcataat acgcctatcc ttttcccttg cttacagcgt
     8581 catttttatc gggtcactga ctgcgccgta atcattaata aatcgccaga tcatttggcc
     8641 tcccgcagaa ttagcaggta aaggtaacgt gagcgtttca aaaggacgga tcatgttgag
     8701 gggcacatca tgaccatcaa cgatgacatc catcacactg atatgaatcg ggttgggatt
     8761 ctctgcaatc aggtttcgcc cttcccggtg ccacttcacc ttcggtgcag catcttcggg
     8821 aatcaggcga atgcttgccg gtcgccagaa cagcttgata cgcgttttaa ctgcgatttc
     8881 cagtgagttc gccgctttgt tgctcgcaga gggcggaata tttttaatat ttagccagaa
     8941 gactgactcg cgatcatcag gcaatgacac acctttggtg tgaataatac gtaatacttt
     9001 ttcttgcgcg ggttctaatc gtgataccgg aggaataacg gtaaacggtg ctttgctttt
     9061 atcctcttta ttaaacggat ctacccatgc ctggatgaga taaggaattt tttcttcctt
     9121 gctaaataca gaaatagatt tatctgggtt attacttaag taaactaccc gtgtaccacc
     9181 aatgacaacg cctgcatagg ttaatgctgg ttggactaaa aaaacactga gtataatcgc
     9241 ggtaaataac ttacatgaaa cggttgtttt aaagagcctg attaaacaac tttttctgga
     9301 cataacgact ccctggccaa agccaactga ataaaaaggc ccttgataaa ttatttctta
     9361 tattcgacag taaattgtga atcggcgttc gccgtacccg ccgttacggt tgcattggtt
     9421 gccacatagc gtgcaataaa cttcatttca gccttgcctt ccgcgtcgat agcggtatag
     9481 gcagaatcgt tataaagttt aacctgcgag ttatctgact ggttaaaaat acgaataccg
     9541 acacccgttg ccgcaatcgc ttgtcctgta ccggtaaaat cgccagggtt gcccgctgta
     9601 agcggcgtac ccactttcag gtcgccgtcg ccgccaggcg cttctgtacc atcaaaacga
     9661 acggctgcct gagtgtaggt tgccgggcac ttttcaagct taatactgaa ctgctgtggt
     9721 gacgccagac tacctacacc tgaaaaagca tttttactga ctttacccag tgggacggtt
     9781 tgatcggctg tatcggaggt aacttcacaa gtagtgtcga caatttcacc gacgaagtga
     9841 acaacaccat cttctgccag tgcatgtccg gccagcatta aagatgccag agtgaatgca
     9901 ccgcctataa tattacgctt cataaaaact ccattgatat aatatatcct ttaccatgaa
     9961 tcatcactta aaataataag tgtgctttga ttcacaggca tagtacacca atgagatagt
    10021 tttatctaaa aataatatta attactcaat cttaaatata aatttattat ttaaatatta
    10081 ttaaaacagc aagaaatcaa gtttattatc agacattatc aataattcag aatatattta
    10141 tatcaatggg tatatgaata atggaattat tgatatcact tataaaaaaa gggccgccgg
    10201 tcggcagccc ttttctatca acgagagata ttactcaacc gttaccgatt ttgccaggtt
    10261 acgcggctgg tcaacgtcgg tgcctttgat cagcgcaacg tggtaagcca gtagttgcag
    10321 cggaacggtg tagaagatcg gtgcaatcac ctcttccaca tgcggcatct caatgatgtg
    10381 catgttgtca ctgctcacaa aacccgcatc ctgatcggcg aagacataca actgaccgcc
    10441 acgcgcgcga acttcttcaa tgttggattt cagtttttcc agcaattcgt tgttcggtgc
    10501 aacgacgata accggcatat cggcatctat cagcgccagc ggaccgtgtt tcagttcgcc
    10561 agcagcgtag gcttcagcgt gaatgtaaga gatctctttc agcttcaatg caccttccag
    10621 cgcgattggg tactgatcgc cacggcccag gaacagcgcg tgatgtttgt cagagaaatc
    10681 ttctgccagc gcttcaatgc gtttgtcctg agacagcatc tgctcaatac ggctcggcag
    10741 cgcctgcaga ccatgcacga tgtcatgttc aatggaggca tccagacctt tcaggcgaga
    10801 cagcttcgcc accagcatca acagcacagt taactgggtg gtgaatgctt tagtagacgc
    10861 cacgccgatt tccgtaccgg cgttggtcat cagcgccaga tcagattcgc gtaccagaga
    10921 agaacccgga acgttacaga tagccagcga accaaggtaa cccagatctt tcgacagacg
    10981 caggcccgcc agggtatccg cggtttcgcc agactgcgac agagtgatca tcaagctatt
    11041 gcgacgcaca gcagatttgc gatagcggaa ttcagaggcg atttcaacgt cgcacggaat
    11101 gcctgccaac gattcaaacc agtaacggga aaccataccg gagttgtaag aagtaccgca
    11161 ggcgaggatc tgaatatgct caaccttcga cagcagttcg tcggcgttcg gtcccagctc
    11221 gcttaaatct acctgaccgt ggctgatgcg cccggtaagg gtgtttttga tcgcgttcgg
    11281 ctgttcgtag atctctttct gcatatagtg gcggtaaata cctttatcgc ccgcgtcata
    11341 ttgcagattg gattcgatat cctgacgttt tacttccgcg ccagttttat cgaagatgtt
    11401 taccgaacgg cgagtgattt ccgcaatatc gccctcttca aggaagataa agcgacgggt
    11461 cactggcaac agcgccagct ggtcagaagc gataaagttt tcgcccatgc ccagaccaat
    11521 caccagcggg ctaccagaac gtgccgccag cagggtatcc gggtgacggg agtccatgat
    11581 cactgtaccg tacgcaccac gcagttgcgg gatagcacgc agaactgcct cacgcagagt
    11641 accgccttgt ttcagctccc agttcaccag atgggcaatc acttcggtgt cggtttcaga
    11701 aacgaaggta tagccacgcg cttttaactc ttcacgcagc ggttcatggt tttcgatgat
    11761 gccgttatgc accaccacaa tgtgttcaga aacatgcgga tgcgcgttag cttctgaagg
    11821 ttcaccgtgg gtcgcccagc gagtatgagc aataccggtg ccgccatgca gaggatgttc
    11881 ttccgctgcc tgagccagca tctggacttt accgaggcga cgcaggcggg tcatatgacc
    11941 ttctgcatca acaacggcca gaccggcaga gtcatatccg cggtattcaa gacgacgtaa
    12001 accttcaaga aggatttctg ctacatcacg ttgcgcgatc gcgccaacaa ttccacacat
    12061 agtttttgat tccgatttat atcgttgtcg gtcaacctgt atgcccgttt tttcgggcgc
    12121 cccgagcctt gtagagagtg gggttatttt tatagttact gcttgtgggc gggagattat
    12181 gttatctcct catcccatat gaccggattt cccagccaga attacttttt ctttaccgga
    12241 cgacgccagc cttctttctg agtctgcggc acacggctga tcgccagggc attttcgccg
    12301 acattacgcg tcacagttgt acccgcagca atggtcgcgc ctttgcctac tgttaccggg
    12361 gccaccagct gagtgtcgga accgacaaac acatcgtcgc cgataatggt cttaaattta
    12421 ttcgcaccgt cgtagttgca ggtaatggtt cccgcgccga tgttaacgtt atcgccaatt
    12481 tccgcatcgc ccaggtaagt cagatgacca gctttcgagc ctttacccag acgcgctttt
    12541 ttcatctcaa cgaagttacc gacgtgtgca ccttccagca actcagcacc aggacgcaga
    12601 cgggcaaacg ggccaatggt acaggccgcc gccagattcg cgtcttccac aacggtatac
    12661 gggctaattt cgcaatcatc gccaatcacg ctgtttttaa tcacacaacc ggtgccgatt
    12721 ttcacgcgat gaccgagagt cacgttgccc tcgatgataa cgttagtatc aatttcaaca
    12781 tcgcgcccgt gagtaagcgt accgcgcaga tcaaaacgcg ccggatcgcg cagcataacg
    12841 cctgctaaca gcagtttttc agcctgttcg aactggtaaa cgcgctccag tcgggagagt
    12901 tgcaggcggt tattcacgcc ttctacttcg cttaaacgtt gcggatgaac ggcgacgatt
    12961 tcacgtcctt cctgatacgc cagcgcaata atgtcggtga tgtagtattc accctgagcg
    13021 ttattgttgg tcagcttcgc cagccagcgt ttcatatctg cgccgttggc aatcagaatg
    13081 ccggtgttga tctcctgaat ctgacgctgc tcgtcggtgg cgtctttgtg ctcaacaatg
    13141 ccggtaactt tgccgttttc acgggtgata cgtccataac cggtcggatc atccagtttt
    13201 accgtcagca gaccaatgcc accctgcggt ttagcatcac gcaggcgctg gagtgtttcg
    13261 acagagatca gcggcacgtc gccgtagagc attaaaatgt cttcatcatc ggcaaagaaa
    13321 ggtgcggcct gctgcatcgc atgacctgta cccagctgtt ctgcctgaag cacccagttc
    13381 aggttgtcat ctttcagcgc ctgtttaagc agatcgccgc cgtgaccgta aaccaggtga
    13441 acgtgcgctg cgcctaattc attcgcagca tcaatgacat gctgaaccat cgctttcccg
    13501 gcaagggtat gcagcacttt cggaagatcg gaatacatgc gcgtgccttt gcctgcggca
    13561 aggatcacta cgctcatagc attattcaac atacgcgtcc tgactgtaat ttgagaacga
    13621 atttaaaccg cttcaccttg aaaaaactac atttttttca tcgtgaaatg gacagaggat
    13681 aaattgttca ataacggatt atccccgctg acgaaagcgc cattttcgac catcgtcacg
    13741 ccttttgtct gcagaaaatt aaggcaatac cttcatttaa gcgtcaggtg gatgtttttg
    13801 ctcttatttc gatcaatgaa taaacgggaa aacagggggt tttatatcag caggatctat
    13861 gtgaacgctc ttcaggacgg gtcacgcgta aaaaaagcca gcctgtttcc agactggctt
    13921 ttgtgctttt caagccggtg ttacatcgct tttttggtca actcgataac gcgcagctgc
    13981 gcgatcgctt tggccagttc cgcagacgcc tgagcgtaat ctacgtcgcc gtgagagctg
    14041 ctaatgtgct cttcagcctt acgtttcgct tccatggctc gcgcttcgtc gagatcctgg
    14101 ccgcgaattg cggtgtcggc cagaacggtc acgttgccag gctgcacttc aagaatgccg
    14161 ccagacagat agataaactc ttcgtgaccg tgctgtttca cgatgcgaat cataccaggc
    14221 ttaatggcgg tgagcagcgg tgcgtggcca gggtagatcc ccagttcacc ttcgctaccc
    14281 gttacctgga ttttctcgac cagaccagag aacatttgtt gctctgcgct gacgacgtcc
    14341 aggtggtaag tcattgccat atcaccctcc gattaaggcg ttaaagtttt ttggcttttt
    14401 ccacagcttc ttcgatggaa ccgaccatgt agaacgcctg ctccggcagg tgatcgtatt
    14461 cgccttccat gatgccttta aagccacgga tggtgtcttt cagggagacg tatttacccg
    14521 gagaaccggt gaatacttct gccacgaaga acggctggga caggaagcgc tggatcttac
    14581 gagcacgcgc taccaccagt ttgtcttctt cagacagttc atccataccc aggatggcga
    14641 tgatgtcttt cagttcctga taacgttgca ggatggactg aacgccacgc gcggtgtcgt
    14701 agtgttcctg accaaccacc agcgggtcca gctgacggct ggtggagtcc agcgggtcaa
    14761 cggccgggta gatacccaga gacgcgatct gacggctcag taccacggtt gcgtcaaggt
    14821 gcgcaaaggt ggttgccgga gacgggtcag tcaagtcatc cgcaggtacg tataccgcct
    14881 gtacggaggt gatagaacca gttttggtgg aggtgatacg ttcctgcaga acgcccatct
    14941 cttccgccag ggtcggctga taacctaccg ctgaaggcat acggcccagc agtgcggata
    15001 cttccgtacc ggccagggtg taacgataga tgttgtcaac gaacagcaga acgtcacgac
    15061 cttcgtcacg gaatttctca gccatggtca gaccggtcag agcaacgcgc agacggtttc
    15121 ccggcggctc gttcatctgg ccatacacca gggatacttt gtcgataacg ttggagtcgg
    15181 tcatttcgtg gtagaagtcg ttaccctcac gagtacgttc acctacgccc gcaaacacag
    15241 agtaaccgga gtgctcgatc gcgatgttac gaataagctc catcatgttt acggttttac
    15301 ctacacccgc accaccgaac agaccaactt taccgccctt agcgaacgga cacatcaggt
    15361 cgataacttt gataccggtt tccagcagtt cctgagagtt tgacagctct tcgtaggaag
    15421 gtgctgcgcg gtgaatcgcc caacgctctt cttcaccgat ctcgcctttc atgtcgaccg
    15481 gttcacccag tacgttcatg atacggccca gagtcgcttt acctaccggg acttcgatcg
    15541 ggtgttcgag gtcttttaca tccagaccgc gacgcagacc gtcggaggaa cccattgcga
    15601 tggtacgcac gataccgccg ccgagctgct gctgaacttc cagcaccaga cgctcattac
    15661 cattttgcac ctcaagagca tcgtacacgc gcggtacggc atcctgaggg aattcgacgt
    15721 caactacggc gccgattacc tggacaatct ttccagtagc catcttaaat cctctacgaa
    15781 ataacctgtt taaaccgcgg cggcccccga gacgatctcg gtgagttcct gagtaatgct
    15841 ggcctgacga gctttgttgt ataccaactg cagctcttta atcaggctgc cgccattgtc
    15901 ggtcgcggct ttcatcgcca ccatacgggc ggcctgctcg ctggccaggt tttcaaccac
    15961 gccctgataa acctgagatt cgacataacg acgcagcagg gtatccagca acgccttcgg
    16021 atcgggttcg tacaggtaat cccaggattt atgtttcaga tcatcatcat ctgatgccgg
    16081 taacggcagc agctggctga tggtcggaac ctgagacatg gtgttaataa atttgttgct
    16141 gacaatgtaa agcttgtcca gacggccttc gtcgtaggcc tgcaacatca cttttaccgg
    16201 accgatcagt tcggacaggg aagggttatc ccccatgccg gtgacctggg caacaacatt
    16261 gccgcccacg gagttgaaga acgacacgcc tttcgagccg atcattgcga ggtcgcattg
    16321 aacgcctttg tcggtccagg tcttcatttc cgccagcagt tttttgaaca ggttaatgtt
    16381 caaaccaccg cacaaaccac ggtcggtcga caccaccagg tagcccacgc gtttaacgtc
    16441 gcggtcttcc aggtaagggt gcttatattc cagattaccg tgtgcaaggt gaccaatcac
    16501 tttgcgcatg gtttctgcat aaggacggct ggccgccatg cgatcctgcg atttacgcat
    16561 tttggaagcg gcgaccatct ccatcgcttt agtgatcttt tgcgtgttct ggacgcttgc
    16621 gatcttacta cgtatctctt ttgcgccggc catgagcttc tcctcaatgc cttgcggcct
    16681 gccctaaggc aagccgccag acgttaccag gattgggttg ctttgaagga atcgaggatg
    16741 cctttcagct tgccttcgat ttcgtcgttg tagccaccgg tctggttgat ctcttgcatc
    16801 aacggagcgt gatcacggtc gacgtaagcc agcagagcgg cttcgaaact gccgattttc
    16861 gacagttcaa catccgccag gtaaccacgt tctgctgcga acagaaccag agactgttgc
    16921 gctacggaca tcggcgcata ctgtttctgt ttcagcagtt cggtcacttt ctgaccgtgg
    16981 tcaagctgct tacgtgttgc atcgtcaagg tcggatgcaa actgagagaa cgctgccagt
    17041 tcacgatact gtgccagagc ggtacggata ccaccggaca gttttttcat gatcttggtc
    17101 tgtgctgcac caccaacacg ggatacggaa atacccgggt taaccgcagg acgaataccg
    17161 gcgttgaaca ggttggtttc caggaagatc tgaccatcgg taatggagat tacgttggtc
    17221 ggaacgaacg cagaaacgtc acccgcctga gtttcgataa tcggcagcgc ggtcagagaa
    17281 ccggttttcc ctttcacttc acctttggtg aaggcttcaa cgtattcggc gttaacacgc
    17341 gcagcacgct ccagcagacg agagtggagg tagaatacgt cgcccgggaa tgcttcacgt
    17401 cctggcggac gacggagcag cagggagatc tgacggtaag caacagcctg tttagacagg
    17461 tcatcgtaaa tgatcagcgc atcttcaccg cggtcacgga agtattcgcc cattgcgcaa
    17521 ccggcatacg gagccagata ttgcagtgca gcggattcag acgcggttgc taccacaacg
    17581 atggtgttag ccagtgcgcc gtgctcttcc agtttacgta ccacgttaga aatggtggac
    17641 gctttctggc cgatagcgac atagatacat ttgataccgg aatcgcgctg gttgatgatg
    17701 gcatcgatag ccagtgcggt tttaccggtc tgacggtcac cgatgatcaa ttcacgctga
    17761 ccacgaccaa ttgggatcat ggagtcaacg gctttataac cggtctgtac cggctgatct
    17821 acggactgac gttcgataac gcccggagcg attgcttcta cagcagagaa gccgtcgtga
    17881 tccagcggac ctttaccgtc gattggtgca cccagagtgt taaccacacg gcccagcagg
    17941 ccacggccaa ccggaacttc caggatacgg ccagtacact taactttcat gccttcggca
    18001 aggtcagcgt acggacccat aacaaccgca cctacagagt cgcgctcgag gttcagtgcg
    18061 atagcgtaac ggttacccgg cagggagatc atttcaccct gcatacaatc ggccaggccg
    18121 tgaatgcgga taacaccgtc acttacagaa acaatagtac cttcgttgtg agcttcactc
    18181 acaacattga actgagcaat gcgctgcttg atcagttcgc tgatttcggt ggaattcagt
    18241 tgcatgctcc agtcccctta agactgcaag acgtctgcaa ggcgctcaag acgaccgcgt
    18301 acgctgccat caatgaccat atcacccgct cggatgataa cgcctgccat tacagactta
    18361 tcgattttgc aattcagctt aactttgcgt gacagacgtt tttccatcgc agcagaaatt
    18421 ttcgcgagct gttgttcact caacgcggca gcggaaatga cgtctacctc agcggtagcc
    18481 tcactcacgg cacgcaggtg aataaactgc tccagaacat ccgggagcgc gttaagacga
    18541 ccattttcag ccattacccg aatcaggttc tgaccgtttt cgtccagttg ctcaccacaa
    18601 actgcgataa acgactcggc gagcgtttct ggcgcaagcg cgccagagag aagctctgcc
    18661 atttgttcgt ttttggttac ctcggcggca aacgccagca tgtcctgcca gcgttctaca
    18721 ctttggtgtt cgacggcaaa gtcaaaagct gctttggcgt aggggcgagc taccgtaata
    18781 aattcagaca tcagcccctc cctccttaca gttcagcgac aagtttatcc acgatgtcgc
    18841 tgttagcagc ttcatccacg gaacgttcga tgatcttctc ggcgccagca acagccagga
    18901 tagcaacttg cttacgcagc tcttcacggg cacgtttacg ctcggcttca atttccgcct
    18961 gcgcctgggc cacgatttta gtacgttcct gctctgcttc agctttagct tcgtccagaa
    19021 tctgcgagcg gcgtttgttc gcctgctcga tgattacctg ggcttccgct ttcgcttttt
    19081 tcagctggtc ggtcgcgctg gcctttgcaa ggtcaaggtc cttatgtgct cgttctgcgg
    19141 aagcaaggcc gtcagcaatt tctttttgac gtttttcgat ggctgccatt aatggcggcc
    19201 atacgtactt catgcagaac agaacgaaca ggacaaacgc gatggcctgg ccgaggattg
    19261 ttgcgttaag attcacagca caatgcctct atttagttaa cgttctgata ttgctcttta
    19321 aataaaagca acgcttacta cgcgacagcg aacatcacgt acagacccag acctacagcg
    19381 atcatcggga tagcatccac cagacccata acgataaaga actgagtacg cagcagagga
    19441 atcagatcag gttgacgcgc tgcgccttcc aggaatttac ccccgaggat gccgataccg
    19501 atcgcagcac cgattgccgc cagacccatc atcacagcgg cagccatgta cagcagatcc
    19561 atattcaggt tttccatgac agtctccagt ttgtttcagt taaaacgtag tagtgttggt
    19621 aaattaatgt tcttcagacg ccatcgacag atagacgatc gtcagaacca tgaagatgaa
    19681 ggcttgcagc gtaatgatca ggatgtggaa aatggcccac ggcacattca gaatccactg
    19741 tgaccaccac ggcaacagac cagcaatcag aatgaaaatc agctcaccgg catacatgtt
    19801 accgaacagt cgcaaaccga gtgaaactgg tttggacagc aggcttaccc cttcaaggat
    19861 taagttgaca ggaatgaacg cccagtgatt gaacggctgc agcgtcaact ctttcgtgaa
    19921 gccgccgatg cctttcattt tgatgctgta gaacagaatc aggataaata cgcccagtgc
    19981 catagacagc gttacgttca cgtccgcaga cggaaccaca cgcagtgccg gcagccccag
    20041 tacatgttca gcaatgtacg gcagcaggtc gataggcagt aaatccatca ggttcatcag
    20101 gaatacccag acgaagatcg tcagggccag cggagcaatc agcttgcttt tgccatggta
    20161 catgtctttc acgctaccat taacaaagcc gatcaccagc tcaatcgcgg tctgaaactt
    20221 acctggcaca ccgctggtcg cctttttggc tacgctacgg aataaaacca ggaacaacag
    20281 acccagcacc accgagaaga acatggagtc aatattgatt gtccagaagg tggctggggg
    20341 gttatgtgga tccaccagcg agaatgtacg caggtccagc tgaaggttat tcaggtggtg
    20401 tcctatgtaa tcctgcggcg tcatattttc tgaagccatg atgcctttta ccctttgttg
    20461 ttaattacag ccggtgccag tatctgaacc accagcacca aaacccacgt aacgatcagc
    20521 ggcaagaata ccgcctttaa aaccgccaac gccaccacca gtaacaccaa catcgccaga
    20581 actttgaaag cttcgccaaa tgcgaatgtc caggccaccc ggcctttcgc tggtgtatgc
    20641 gcctggtgac gccaggcaaa tatcataaac aaaacgttag gcagaaagac tgccaggccc
    20701 ccgcttattg cagagacgcc ccagaagggg tctttgaggc tgaacagcaa tccacttgct
    20761 atcaccacca gtaactgaac gagcagaagc ttccgagcaa cgtttcgact cacgagcgac
    20821 acagacatca cgtttttcac tcctgctccc ttcgaggtat gccgcgtgtc gtataaaact
    20881 ttctttaagg cttagagtca agcatcaaaa agcggtcaaa ttatacggtg cgcccccgtg
    20941 atttcaaaca ataagtagcc aaaaggtgaa taaatgttta aatatttttc cagtgcatac
    21001 aattgcgact tttctgctaa ccctgttcga tcatgaaaaa ctgtaaataa cgcgtaaaca
    21061 ctggtgataa agcgtgcttc agatcacata ttgcgcatgt tcgcgcacag catatttatt
    21121 tacttggcaa atgatgcctt tgcaagttta tgatatttca gtctaaaaac agatactgtt
    21181 ttaataaatg acatttacac aacaaaaacc acccattgac atttttaata atgttttaac
    21241 agccaatgat ggttcttagc gccgattttt agcagactga tattttcact aatgacttat
    21301 tttctgctta ccaaaaaaag ccacgttatc ttgttgatgc aaaagagtga acgtggcgtt
    21361 aaatgtaacc agttatatca gtagaaaacc tggttgttgt taacagtcta accggtcaat
    21421 tttttatgat ttttttgata aaaattaaat tttatttgct ttaatcacca ccagatgacg
    21481 ttcgccatcc agggctggaa cctgaagttt aaccactgat tcgacctgat attcttcggg
    21541 caacaaagcg atttcatctt ccggcatttg ccctttcagc gcgtagaaac ggccttgctc
    21601 accaggaaga tggtggcacc agctcaccat atcgttcaga gaggcaaaag cgcggctaat
    21661 tacgccatca aatggcggct ctgaaggaaa ctcttctacc ctgctctgta ctggctcaat
    21721 attctccagt ttaagctcat gttgcacctg acgaaggaaa cgcacgcgtt taccaaggct
    21781 atccaacaga gtgaaatggg cttcaggacg cacgatcgag agtggaatgc ctggcagtcc
    21841 tggtccggtg ccgacatcga taaaccgttc accttgcaga tacggtgcca ccacaatgct
    21901 atcgagaata tggcgtacca gcatctcatt aggatcgcga accgaagtca ggttgtacgc
    21961 tttgttccat ttatgcagca tattcacgta ggcaataagc tggtttttct ggtgatcggt
    22021 aagcgaaata cctgcgtctt tcagcagtaa ggagagtttg ttgagcacgg tgattacctg
    22081 ttcttgatgc gttgcccggt aagcgggtgc ttaccaggca tttttaatgc gttatgcgct
    22141 acgacgcagc ataccctgtt ttttcagcca caccagcaga atggagatgg ccgcaggcgt
    22201 gacgccagaa atacgcgaag cctggccgat agaggccggt ttgtgatcgt taagtttggc
    22261 gatcacttcg ttagaaagac cggatacctg gcggtaatcc agtgtcgcgg gtagcagggt
    22321 gttctcgtta cgcagctgct tttcgatctc atcttgctgg cgcgcgatat aaccttcgta
    22381 tttaacctga atctcaacct gttccgccgc ctgttcgtct gtcaacgcag gggcaaacgg
    22441 cgtcagcgtg gttaattttt cataagtcat ttccggacga cgcagcagat cttcaccact
    22501 ggcttcacgg gaaagcggcg cagtcaggtg agcattcact tcggctgcag cttccgccga
    22561 cggggttacc caggtcgatt tcagacgctg acgctcacgc tcgatattct caagtttctc
    22621 gttaaagcgc gcccaacgtt cgtcatccac caggcccagt tcacgaccga tttcagtcaa
    22681 acgcagatcc gcattatctt cgcgcagcat cagacgatat tctgcgcgcg aagtaaacat
    22741 acgatacggt tctttggttc ctaaagtgca caggtcatca accagtacgc cgagatacgc
    22801 ctgagaacgt gccggagccc aaccttcttt gtcagcagac agacgggcag cgttaagacc
    22861 ggccagcaaa ccttgcgcag cggcttcttc gtaaccggta gtgccgttaa tctgaccagc
    22921 aaagaacagc ccctggataa acttgctctc cagcgtcggt ttcaggtcgc gaggatcgaa
    22981 gaagtcatac tcaatggcat aacccggacg cacgatcttc gcgttttcca tcccctgcat
    23041 agagcggacg atttgcatct gcacatcgaa cggcaggctg gtggagatac cgttcggata
    23101 aatttcgtta gaggtcagtc cttccggttc aaggaagatc tgatgctgat ttctgtcggc
    23161 gaagcgcatg actttgtctt cgatggacgg gcagtagcgt gggccgacac cttcgatcac
    23221 ccctgcatac attgggctac gatcgaggtt actgcggatc acatcatggg ttttctcgtt
    23281 ggtatgagtg atataacacg gcacctgctg gggatgctgg gacgcattgc ccataaacga
    23341 gaataccggc attgggttat cgccatgctg ttgcgccagc acactaaagt cgatagttcg
    23401 agcatcaata cgcggtggtg tcccggtttt cagacgacca acgcgcagcg gcagttcacg
    23461 caaacggcga gaaagcggaa tggacggcgg atcaccagca cggccaccgc tgtaattatc
    23521 cagaccgata tgaattttac cgtcgaggaa tgtcccaacg gtgagcacga cggctttggc
    23581 acggaacttc agtcccattt gggtaatagc accgaccacg cgatcgtttt cgacaataag
    23641 atcttcaacc gcctgctgga agatcatcag gttcggttgg ttctccagcg ccgtacgtac
    23701 cgcctgacgg tagagcacac gatccgcctg agctcgggta gcgcgaaccg ccggtccttt
    23761 gcttgcgttt agtatcctaa actggatacc cgcttgatcg atcgctttcg ccatcagacc
    23821 gccgagtgca tccacttctt ttaccagatg tcccttccca ataccgccga tcgccgggtt
    23881 gcagctcatc tgccccagag tgtcgatatt gtgtgtcaaa agcagagtct gttgacccat
    23941 acgcgccgcg gccatcgcgg cctcggtgcc tgcatgaccc ccgccaatga tgatgacgtc
    24001 aaaaggatcc ggataaaaca tggtgattgc ctcgcataac gcggtatgaa aatggattga
    24061 agcccgggcc gtggattcta ctcaactttg tcggcttgag aaagacctgg gatcctgggt
    24121 attaaaaaga agatctattt atttagagat ctgttctatt gtgatctctt attaggatcg
    24181 cactgccctg tggataacaa ggatccggct tttaagatca acaacctgga aaggatcatt
    24241 aactgtgaat gatcggtgat cctggaccgt ataagctggg atcagaatga ggggttatac
    24301 acaactcaaa aactgaacaa ccgttgttcc ttggataact accggttgat ccaagcttcc
    24361 tgacagagtt atccacagta gatcgcacga tctgtatact tatttgagta aattaatcca
    24421 cgatcccagc cattcttctg ccggatcttc cggaatgtcg tgatcaagaa tgttgatctt
    24481 cagtgtttcg cctgtctgtt ttgcatcgga atttttgagt tctgcctcga gtttatcgat
    24541 agccccacaa aaggtgtcat attcacgact gccaataccg attgcgccaa agcggactgc
    24601 agaaagatcg ggcttctgtt cctgcaatgc ttcatagaaa ggagaaaggt tgtccggaat
    24661 atctccggca ccgtgggtgg agctgataat cagccagatc cccgaggcag ataaatcttc
    24721 caacagcgga ccgtgcagcg tttcggtggt aaaacccgcc tcttccagct tttcagccag
    24781 gtgttctgct acatattcgg caccgccgag ggtgctgccg ctgataagag tgatatctgc
    24841 cataaaccgc cacctttatt aagagtggcg tattgtacgc tgtgaacgcg ttgggatcta
    24901 cctgtggaaa agtatgggat taaaaaagcc gatcatggct tgatagtacg catgatcggg
    24961 ttttgcagga cgatcaatgt ctcagtggac tgaatttcat caattgtttg gatcttgttg
    25021 ataagtacat gctggagagc gtcgatcgaa cggcacatta cttttataaa gatgctgtag
    25081 tggcctgttg tgtaataggc ttcagtgact tcatcaaggc tttccagctt tgccagcgcg
    25141 gaagggtagt ctttggcgct ctttaatata atgccgataa agcagcctac gtcataaccg
    25201 agctgcttcg ggctgacatc aatacgcgcc ccggtaatga tccccgcctg cttcattttc
    25261 tctactcgaa cgtgaatcgt ccccggactg acgccaaatt gtttcgccag ttcggcgtaa
    25321 gcggtgcgcg cattgcccat taatgcttcc aggatgccac ggtccagatt gtcgatcaga
    25381 taattttcca taggattttc ttatgcagat tgatgattca ttctatttta gccttctttt
    25441 ttaatgaatc aaaagtgtgt taggcttttt attgaatgat tattgcatgt gtgtcggttt
    25501 ttgttgctta atcataagca acaggacgca ggagtataaa aaatgaaaac cgcttacatt
    25561 gccaaacaac gccaaattag cttcgtgaaa tctcactttt ctcgccaact ggaagaacgt
    25621 ctggggctga tcgaagtcca ggcgccgatt cttagccgtg tgggggatgg cacgcaggat
    25681 aacttgtcgg gctgtgaaaa agcggtgcag gtaaaagtga aagctctgcc tgatgcccag
    25741 ttcgaagtgg ttcattcact ggcgaagtgg aaacgtcaga ccttagggca acacgacttc
    25801 agcgcaggcg aagggctgta cacgcacatg aaagcccttc gccccgatga agaccgtctt
    25861 tctccgttgc actcggtcta tgttgaccag tgggactggg aacgcgtaat gggcgacggt
    25921 gagcgtcaat tctcgactct gaaaagcacg gtagaggcga tctgggcggg aattaaagca
    25981 accgaagctg cggttagcga agagtttggc ctggcaccgt tcctgccgga tcagatccac
    26041 ttcgtacaca gccaggagtt actgtctcgt tatccggatc tcgatgccaa agggcgtgag
    26101 cgggcgatag cgaaagatct tggcgcggta ttccttgtcg ggattggcgg caagctgagc
    26161 gatggtcatc gccacgacgt gcgcgcaccg gattatgatg actggagcac cccgtcagag
    26221 ctgggccatg cgggtctgaa cggcgatatt ctggtgtgga accctgtact ggaagatgcg
    26281 tttgagcttt cttccatggg gatccgcgtg gatgccgaca cgttgaagca tcagttggcg
    26341 ctgaccggtg atgaagatcg tctgcagctg gaatggcatc aggcgctgct gcgcggtgaa
    26401 atgccgcaga ccatcggcgg cggtatcggc cagtctcgtt tgaccatgct gctgctgcaa
    26461 ctgccgcata tcggccaggt tcagtgtggt gtatggccag ctgctgttcg cgagagcgtc
    26521 ccttctctgc tgtaataatt tatcgccgcc agcgtctgag caggcggctt cgcatcccgg
    26581 tatcaaagcg ccagatatga tcgaaaatgc gcatgatgcc gggtttgccg tgtgccgaca
    26641 tcgccacggc atgaaagcga tgctgatgta cccgctgcag ctctttcact ttacttgtca
    26701 cgtcgtcagg caaccgctga gcgataaaat cagaaatcac caccgcatcg gcatcaaacc
    26761 attccctgct ttgcaagcgt tccataatgg cgcgaaaaca actggcaaga tcggtgccgc
    26821 cacgaaactg ctggcttaaa aaacggattg cttgttcgat gccttgtggg cctgaaagct
    26881 cataacggac gatctcggtg gaaaatagca taatatagca gcgccggttt tcagcgagag
    26941 caatgcgcat caaggccagg cagaacgctt tcgcacactg ttcattaaag ccgcccattg
    27001 agccggaagt atccacgcag acaataaacg gtccgcgcgg ctgttcgtcg taatctttat
    27061 gcaccaccgg gcgttcgatc actttttcac gccacgactc accgtgcagg cgataggtga
    27121 gcaactgttt ttccaccagc cgacggtaaa actcatactc cagttccgtt atccctagtg
    27181 tcgccagttc tggaggcagg agacgtaaaa tatcatcgct ttgttgcaga ccatcaacct
    27241 gctcaggaac cgtcgccggt tcgcgcacca tggtgcggaa ggtttccatc tgcgcatcgt
    27301 tgcgcggtat tgatttggct tcccgggaac gccccagttg ttctgccagg cgtttcagtt
    27361 ccggctgttc gttaagaaat tcaccgtatt tcacaatcaa ctgatagtcg ccacgtttaa
    27421 gctgaccggc gctcatatcc cacagacgac cagctgcggt attgttatct gcgagaatcg
    27481 gttcaagttg tccgctcagc gtcatgcgtt cctgaacttc actcaacagt tgttcgcgtt
    27541 cttcttctaa tagctgttga tttaacgtcg ttgcttgcac gatcagactt aaacgccaac
    27601 gctggagaaa aagcgtgtgt aacgctgaag tgatcgtgct gttagcatca accaactgtc
    27661 gggcttgttc tgcccatgga gaattcagac gatgcagtaa gtccaggatc tgtggtagct
    27721 gcacaataaa ctgcggcgtg gagaggagct ggctttgctg atagcacatc acctcttcgg
    27781 tgagttccgg cgggactcgg gcatctttca gccgactgcg cagtgcctca cgccagcggg
    27841 gaacatcatc agtgattgcc gccttcagtc gtgggaattt ttcaaagaag actgccagct
    27901 gcggtgaggc cagcagcgcg atgatcatct cttcgatcaa tccctcttcg ctgacggcca
    27961 gcatcacatt aagcgtatcc agcgttagca ttgttgtgcc tggcgaatct gtgcgccgac
    28021 atcttgtagg ctggcttcaa tgcgacctaa ccagtcgcca gagataaaca gacatttttg
    28081 ctgttcgctg aataaaacgt gttgcttgcg ccagtcgctt tcaagctctt ccagttgttg
    28141 ttttatttca cctggcagac cttcagccga tgaaccggga agtgccagcg tactgccttg
    28201 taaacttaca tcgcgtacaa caagatgttg ggtgctatca acttccagat tcagtttctg
    28261 ggcaaagcca ataccgttca gtttgccgcg aatttcacca cctttactca gccactgttc
    28321 cagcgcgtta cgctcaaagg agatatgaac cacttccata tcatgcaatt ttaacggttt
    28381 ttgcagcagc agagtcagag tggaagcagt aacgttaaca ggaagttgat actgctgacg
    28441 acggctgaaa atgccgccca gacgaattac cgttaaggct gttttatcgc tttgttgctg
    28501 ctggagttgc aggtgacgtt gcacaatcgc gcccaggcgg gtcaacatcc cttgctgttg
    28561 ccaggcatga ccggtcatca atacatcaat ttgttgttgt atcaaattca ggctttgcgc
    28621 gtcataccac aggcaatctt tcagcaaaat gagatcaacc ggggcaacag cactgcgacc
    28681 gctaaaaaag gcgctggcct gcaataatcg aatcgctttt ttccagcgac gatccgagac
    28741 ataaggcgca tccggtaatt tatccagttg ctggcgcagc ataaaaatca gctcaaatac
    28801 atgatcgggc agcgtaattt caccaatctc tttctgccag cgttcatatt cttcatctgt
    28861 gacctgcaag gaggcaggaa ccggattgtc gttttcatcc tgttgactgg tcagcatgga
    28921 gcggaaattc gctttatcct gcactttatc taaccacaga cgaatcagca tgcggtcata
    28981 taacgcttcc agactgctgt ctgcttccgg cagctcgttg gaggccgcca ccagcaggcg
    29041 catcgggatt ttttctacgt gtgcaccgtt gcggaactgg cgctcgttaa tggcggtgag
    29101 cagggtatta agaattgccg gacccgcttt ccagatctca tccagaaaga cgatttctgc
    29161 ttccggcagg taaccgctgg ttaaacgttc atagcgccct tcatctttta gcgcctgaat
    29221 agaaagggga ccaaaaacct cttccggcgt ggagaagcga gtcatcagat attcaaacgc
    29281 gcgggcattc tgaaaggcga attttaagcg ccgggcgatt aaacttttgg caatacctgg
    29341 cgggccaagg aggaacacac tttcaccact taatgccgct aataaacaca agcggatggc
    29401 gtggctacgt tcataaagcc ccttttccaa cgaactgctc aggcgggaaa ttctttccgc
    29461 taataaatga gggtgagcca taatgaagtg gcgtcctttc gtcaaaagtt ctgcgtaaat
    29521 tgcgagtata gacgtttctt gctggtggct aaaatagtct caaaggaggg gtatttttct
    29581 ttgagccagg ttaatgtggc cgcatttagg agtacgattt tgccgttaat cgtgcatact
    29641 gtgcgctttt ttgtgggcca agggactaag cacacatttc atatttcaac gaaagactag
    29701 tctatgagca ctgataataa gcaatcattg cccgcgatta ccctcgcggc gattggagtt
    29761 gtctacggcg atattggtac cagcccgtta tatacacttc gtgaatgttt gtccggccag
    29821 tttggttttg gcattgaacg cgatgccgtg tttggctttt tatcgctgat cttctggctg
    29881 ctaatctttg tggtttccat taaatatctc accttcgtga tgcgggcaga taacgccggt
    29941 gaagggggga tcctgacgtt gatgtcgctt gccgggcgta atacgtcggc gcgaaccaca
    30001 tcaatgctgg tgattatggg gctaatcggc ggcagctttt tctatggtga agtcgtcata
    30061 acacccgcta tttcggtgat gtcagccatt gaaggtctgg aaatcgtcgc cccgcagctg
    30121 gatacctgga tagttcccct ctcaattatc gttctcactt tattatttat gattcaaaaa
    30181 catggcacgg ctatggtcgg taagctgttt gcgccgatca tgctgacctg gtttttgatt
    30241 ctggcagggc tggggttacg tagcattatt gctaacccgg aagtgctgca tgcactgaat
    30301 ccgatgtggg cggtgcattt cttccttgaa tacaaaacgg tttcttttat tgcattaggg
    30361 gcagtggtgc tgtcgattac gggggtcgag gcgctgtatg ccgatatggg gcactttggt
    30421 aagttcccta ttcgcctggc gtggttcacc gtcgtattac cttccttaac ccttaattac
    30481 ttcggtcagg gagcgttgtt gttaaagaac ccggaagcga ttaagaaccc gttcttcctg
    30541 ttggcaccgg actgggcgct gatcccactg ctgatcatcg ccgcactggc gacggtaatt
    30601 gcctcgcagg cggttatctc tggcgtcttc tcattgacgc gtcaggcggt acgtctggga
    30661 tatttgtcgc cgatgcgcat tattcacacc tccgaaatgg agtcagggca aatctatatt
    30721 ccgtttgtga actggatgct ctatgtcgcg gtcgtgattg tgattgtcag ctttgagcac
    30781 tccagcaacc tggcggcggc gtacgggatt gcggtgaccg gaaccatggt gctgacgtct
    30841 attctctcga ctaccgtggc acgtcagaac tggcactgga ataagtattt tgttgcgctg
    30901 atcctgattg ctttcctttg tgtcgatatt ccattgttca ccgctaacct cgataaactg
    30961 ctctccggcg gctggttgcc attgagcctc ggtacggtga tgtttatcgt gatgaccacc
    31021 tggaagagcg agcgtttccg cttgctgcgg cggatgcatg aacatggtaa ctctctggaa
    31081 gcgatgattg cttcgctgga gaaatcaccg cctgttcgcg tgcccgggac cgcggtgtat
    31141 atgtcgcgtg caatcaacgt cattcccttt gcgctgatgc ataaccttaa acataacaag
    31201 gtattgcatg agcgggtgat tctgttaact ctgcgcaccg aagacgcgcc ttatgtccat
    31261 aacgtccgtc gggtacagat tgaacaactg tcgcccactt tctggcgcgt ggtggcaagt
    31321 tatggttggc gagaaacgcc aaacgtggaa gaagttttcc accgctgcgg tctggaagga
    31381 ttaagttgcc ggatgatgga aacctccttc tttatgtcgc atgagtcgtt gatcctcggc
    31441 aaacgcccgt ggtatttgcg tctgcgcggt aagctgtact tgctgctgca acgtaatgcg
    31501 ctgcgtgcgc cggatcaatt tgaaatcccg ccaaacaggg ttatcgaact gggtactcag
    31561 gtcgaaatct aacgccagac gcctcctttc tccataaggg ggcgtttttg ttttcatggt
    31621 taatcaccat gtaaaacgtt tcgaggttga tcacatttcc gtaacgtcac gatggttttc
    31681 ccaactcagt caggattaaa ctgcgggtca gcgaaacgtt tcgctgatgg agaaaaaaat
    31741 gaaaaaaggc accgttctta attctgatat ttcatcggtg atctcccgtc tgggacatac
    31801 cgatacgctg gtggtgtgtg atgctggttt acccatcccc aaaagtacaa cgcgtatcga
    31861 tatggcatta acccaggggg taccttcttt tatgcaggtg ctgggcgtcg tcacaaatga
    31921 aatgcaggtc gaagctgcca ttatcgcgga agagatcaaa caacataatc cgcaactcca
    31981 cgaaacgttg ctcactcacc ttgagcagct gcaaaaacac cagggaaata ccattgaaat
    32041 tcgttacacc acgcatgaac aattcaaaca acaaaccgca gaaagtcagg cggtaattcg
    32101 cagcggagaa tgttctccgt atgcgaatat cattctctgt gctggcgtga cgttctgagg
    32161 ccgtcatgga agcattactt cagcttaaag gcatcgataa agccttcccg ggcgtaaaag
    32221 ccctctcggg cgcagcgtta aatgtctatc cgggccgcgt gatggcgctg gtgggcgaaa
    32281 acggcgcggg taaatccacc atgatgaaag tgcttactgg tatctatact cgcgatgccg
    32341 gcacgctttt atggctgggg aaagaaacga catttaccgg gccgaaatct tcccaggaag
    32401 ccgggattgg gattatccac caggaactga acctgatccc gcagttaacc attgccgaaa
    32461 acattttcct cggtcgtgag tttgttaatc gctttggcaa aattgactgg aaaaccatgt
    32521 atgccgaagc ggataaattg ctggctaaac ttaacctgcg ctttaaaagc gacaagctgg
    32581 tgggcgatct ttccatcggt gaccagcaaa tggttgaaat cgccaaagtg ctgagctttg
    32641 agtcgaaagt catcattatg gatgaaccga ccgatgcgct gaccgatacc gaaaccgaat
    32701 ccttgttccg cgtcatccgc gagctgaaat cgcaaggccg cggtattgtc tatatctccc
    32761 accgcatgaa agaaatcttc gagatttgcg atgacgttac cgtttttcgt gacgggcaat
    32821 ttattgctga gcgtgaagta gcatcactga ccgaagattc gctgattgag atgatggtgg
    32881 gtcgcaagct ggaagatcaa tatccgcacc tggacaaagc gccgggagat atccgcctga
    32941 aagtcgataa tctctgcgga cctggcgtta acgatgtctc ttttacttta cgcaaaggcg
    33001 aaattcttgg cgtctctggt ttgatgggcg caggtcgtac cgaactgatg aaagtgctct
    33061 acggcgcact gccgcgcacc agcggttacg tcaccctgga tgggcatgaa gttgttaccc
    33121 gttcaccgca ggatggcctg gcaaacggca ttgtgtatat ctccgaagac cgtaaacgtg
    33181 acggtttagt gctgggcatg tcagtaaaag agaatatgtc gctgaccgcg ctgcgctact
    33241 tcagccgcgc tggcggcagt ttgaagcatg ccgatgaaca gcaggcagta agtgatttca
    33301 ttcgtctgtt taatgtgaaa acgccgtcga tggaacaggc aattggtctg ctttccggtg
    33361 gcaatcagca aaaagtggcg attgcccgtg gtctgatgac acgccccaaa gtgttgatcc
    33421 tcgatgagcc tacccgtggc gtagatgtcg gcgcgaaaaa agagatctat caactgatta
    33481 accagttcaa agccgatggc ttgagcatca ttctggtgtc atcggagatg ccagaagtat
    33541 taggcatgag cgatcgcatc atcgtcatgc atgaagggca tctcagcggg gaatttactc
    33601 gtgagcaggc cacccaggaa gtgttaatgg ctgccgctgt gggcaagctt aatcgcgtga
    33661 atcaggagta aaaaaatgac aacccagact gtctctggtc gccgttattt cacgaaagcg
    33721 tggctgatgg agcagaaatc gcttatcgct ctgctggtgc tgatcgcgat tgtctcgacg
    33781 ttaagcccga actttttcac catcaataac ttattcaata ttctccagca aacctcggtg
    33841 aacgccatta tggcggtcgg gatgacgctg gtgatcctga cgtcgggcat cgacttgtcg
    33901 gtaggttctc tattggcgct gaccggcgca gttgctgcat ctatcgttgg cattgaagtc
    33961 aatgcgctgg tggctgtcgc tgccgctctc gcgttaggtg ccgcaattgg tgcggtaacc
    34021 ggggtgattg tagcgaaagg tcgcatccag gcctttatcg ctacgctggt tatgatgctt
    34081 ttactgcgcg gcgtgaccat ggtttatacc aacggtagcc cagtgaatac tggctttact
    34141 gagaacgccg atctgtttgg ctggtttggt attggtcgtc cgctgggcgt accaacgcca
    34201 gtctggatca tgggaattgt cttcctcgcg gcctggtaca tgctgcatca cacgcgtctg
    34261 gggcgttaca tctacgcgct gggcggcaac gaagcggcaa cgcgtctttc tggtatcaac
    34321 gtcaataaaa tcaaaatcat cgtctattct ctttgtggtc tgctggcatc gctggccggg
    34381 atcattgaag tggcgcgtct ctcctccgca caacccacgg cggggactgg ctatgagctg
    34441 gatgctattg ctgcggtggt tctgggcggt acgagtctgg cgggcggaaa aggtcgcatt
    34501 gttgggacgt tgatcggcgc attaattctt ggcttcctta ataatggatt gaatttgtta
    34561 ggtgtttcct cctattacca gatgatcgtc aaagcggtgg tgattttgct ggcggtgctg
    34621 gtagacaaca aaaagcagta ataacgacta caggacatct tgaatatgaa tatgaaaaaa
    34681 ctggctaccc tggtttccgc tgttgcgcta agcgccaccg tcagtgcgaa tgcgatggca
    34741 aaagatacca tcgcgctggt ggtctccacg cttaacaacc cgttctttgt atcgctgaaa
    34801 gatggcgcgc agaaagaggc ggataaactt ggctataacc tggtagtgct ggactcccag
    34861 aacaacccgg cgaaagagct ggcgaacgtg caggacttaa ccgttcgcgg caccaaaatt
    34921 ctgctgatta acccgaccga ctccgacgca gtgggtaatg ctgtgaagat ggctaaccag
    34981 gcgaacatcc cggttatcac tcttgaccgc caggcaacga aaggtgaagt ggtgagccac
    35041 attgcttctg ataacgtact gggcggcaaa atcgccggtg attacatcgc gaagaaagcg
    35101 ggtgaaggtg ccaaagttat cgagctgcaa ggcattgccg gtacatctgc agcccgtgaa
    35161 cgtggcgaag gcttccagca ggccgttgct gctcacaagt ttaatgttct tgccagccag
    35221 cctgcagatt ttgatcgcac caaaggtttg aacgtaatgc agaacctgtt gaccgctcat
    35281 ccggatgttc aggctgtatt cgcgcagaat gatgaaatgg cgcttggcgc gctgcgcgca
    35341 ctgcaaactg ccggtaaatc ggatgtgatg gtcgtcggat ttgacggtac accggatggc
    35401 gaaaaagcgg tgaatgatgg caaactagca gcgactatcg ctcagctacc cgatcagatt
    35461 ggcgcgaaag gcgtcgaaac cgcagataaa gtgctgaaag gcgagaaagt tcaggctaag
    35521 tatccggttg atctgaaact ggttgttaag cagtagtttt aatcaggttg tatgacctga
    35581 tggtgacata aatacgtcat cgacagatga acgtgtaata taaagaaaag cagggcacgc
    35641 gccaccctaa cacggtggcg cattttatgg acatcccgaa tatgcaaaac gcaggcagcc
    35701 tcgttgttct tggcagcatt aatgctgacc acattcttaa tcttcaatct tttcctactc
    35761 caggcgaaac cgtaaccggt aaccactatc aggttgcatt tggcggcaaa ggcgcgaatc
    35821 aggcggtggc tgctgggcgt agcggtgcga atatcgcgtt tattgcctgt acgggtgatg
    35881 acagtattgg tgagagcgtt cgccagcagc tcgccactga taacatcgat atttctccgg
    35941 tcagcgtgat caaaggcgaa tcaacaggtg tggcgctgat ttttgttaat ggcgaaggtg
    36001 agaatgtcat cggtattcat gccggcgcta atgctgccct ttccccggcg ctggtggaag
    36061 cgcaacgtga gcgtattgcc aacgcgtcag cattattaat gcagctggaa tcaccactcg
    36121 aaagtgtgat ggcagcggcg aaaatcgccc atcaaaataa gactatcgtt gcgcttaacc
    36181 cggctccggc tcgcgaactt cctgacgaac tgctggcgct ggtggacatt attacgccaa
    36241 acgaaacgga agcagaaaag ctcaccggta ttcgtgttga aaatgatgaa gatgcagcga
    36301 aagcggcgca ggtactgcat gaaaaaggta tccgtactgt actgattact ttaggaagtc
    36361 gtggtgtatg ggctagcgtg aatggtgaag gtcagcgcgt tcctggattc cgggtgcagg
    36421 ctgtcgatac cattgctgcc ggagatactt ttaacggcgc gttaatcacg gcgttgctgg
    36481 aagaaaaaac attgccagag gcgattcgtt ttgcccatgc cgccgctgcg attgccgtaa
    36541 cacgtaaagg cgcacaacct tccgtaccgt ggcgtgaaga gatcgacgca tttttagaca
    36601 ggcagaggtg acgcttggct acaatgaaag atgttgcccg cctggcgggc gtttctacct
    36661 caacagtttc tcacgttatc aataaagatc gcttcgtcag tgaagcgatt accgccaaag
    36721 ttgatgcggc gattaaagaa ctcaattacg cgccatcagc tctggcgcgt agcctcaaac
    36781 tcaatcaaac acataccatt ggcatgttga tcactgccag taccaatcct ttctattcag
    36841 aactggtgcg tggcgttgaa cgcagctgct tcgaacgcgg ttatagtctt gtcctttgca
    36901 ataccgaagg cgatgaacag cggatgaatc gcaatctgga aacgctgatg caaaaacgcg
    36961 ttgatggctt gctgttactg tgcaccgaaa cgcatcagcc ttcgcgtgaa atcatgcaac
    37021 gttatccgac agtgcctact gtgatgatgg actgggctcc gttcgatggc gacagcgatc
    37081 ttattcagga taactcgttg ctgggtggag acttagcaac gcaatatctg atcgataaag
    37141 gtcatacccg tatcgcctgt attaccggtc cgctggataa aactccggcg cgcctgcggt
    37201 tggaaggtta tcgggcggcg atgaaacgtg cgggtctcaa cattcctgat ggctatgaag
    37261 tcactggtga ttttgaattt aacggcgggt ttgacgccat gcgccaactg ttatcacatc
    37321 cgctgcgtcc tcaggccgtc tttaccggaa atgacgctat ggctgttggc gtttaccagg
    37381 cgttatatca ggcagagtta caggttccgc aggatatcgc ggtgattggc tatgacgata
    37441 tcgaactggc aagctttatg acgccaccat taaccactat ccatcaaccg aaagatgaac
    37501 tgggggagct ggcgattgat gtactcatcc atcggataac ccaaccgacc cttcagcaac
    37561 aacgattaca a
//
LOCUS       DADXDL010000042        37474 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.042, whole genome shotgun sequence.
ACCESSION   DADXDL010000042 DADXDL010000000
VERSION     DADXDL010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37474)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37474)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37474
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.042"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(12..260)
                     /gene="hybG"
                     /locus_tag="IRB70_002434"
     CDS             complement(12..260)
                     /gene="hybG"
                     /locus_tag="IRB70_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation factor HybG"
                     /protein_id="HBC0632339.1"
                     /translation="MCIGVPGQVLAVGEDIHQLAQVEVCGIKRDVNIALICEGNPADL
                     LGQWVLVHVGFAMSIIDEDEAKATLDALRQMDYDITSA"
     gene            complement(273..614)
                     /gene="hypA"
                     /locus_tag="IRB70_002435"
     CDS             complement(273..614)
                     /gene="hypA"
                     /locus_tag="IRB70_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase maturation nickel metallochaperone
                     HypA"
                     /protein_id="HBC0632340.1"
                     /translation="MHELSLCQSAVEIIQRQAEQHDVKRVTAVWLEIGALSCVEESAV
                     RFSFEIVCHGTVAQGCDLHIVYKPAQAWCWDCSQVVEIHQHDAQCPLCHGERLRVDTG
                     DSLIVKSIEVE"
     gene            complement(607..1095)
                     /gene="hybE"
                     /locus_tag="IRB70_002436"
     CDS             complement(607..1095)
                     /gene="hybE"
                     /locus_tag="IRB70_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase-2 assembly chaperone"
                     /protein_id="HBC0632341.1"
                     /translation="MTEEIAGFQTSPKAQVQAAFEEIARRSMHDLSFLHPSMPVYVSD
                     FTLFEGQWTGCVITPWMLSAVIFPGPDQLWPLRKVSEKIGLQLPYGTMTFTVGELDGV
                     SQYLSCSLMSPLSHSMSIEEGQRLTDDCARMILSLPVTNPDVPHAGRRALLFGRRSGE
                     NA"
     gene            complement(1088..1582)
                     /locus_tag="IRB70_002437"
     CDS             complement(1088..1582)
                     /locus_tag="IRB70_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HyaD/HybD family hydrogenase maturation
                     endopeptidase"
                     /protein_id="HBC0632342.1"
                     /translation="MRILVLGVGNILLTDEAIGVRIVEALEQRYILPDYVEILDGGTA
                     GMELLGDMANRDHLIIADAIVSKKSAPGTMMILRDEEVPALFTNKISPHQLGLADVLS
                     ALRFTGEFPKKLTLVGVIPESLEPHIGLTPTVEAMIEPALEHVLAALRESGVEAIPRE
                     AIHD"
     gene            complement(1582..3285)
                     /gene="hybC"
                     /locus_tag="IRB70_002438"
     CDS             complement(1582..3285)
                     /gene="hybC"
                     /locus_tag="IRB70_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 large subunit"
                     /protein_id="HBC0632343.1"
                     /translation="MSQRITIDPVTRIEGHLRIDCEIENGVVSKAWASGTMWRGMEEI
                     VKNRDPRDAWMIVQRICGVCTTTHALSSVRAAESALNIDVPVNAQYIRNIILAAHTTH
                     DHIVHFYQLSALDWVDITSALQADPTKASEMLKGVSTWHLNSPEEFTKVQNKIKDLVA
                     SGQLGIFANGYWGHPAMKLPPEVNLIAVAHYLQALECQRDANRVVALLGGKTPHIQNL
                     AVGGVANPINLDGLGVLNLERLMYIKSFIDKLSDFVEQVYKVDTAVIAAFYPEWLTRG
                     KGAVNYLSVPEFPTDSKNGSFLFPGGYIENADLSSYRPITSHSDEYLIKGIQESAKHS
                     WYKDEAPQAPWEGTTIPAYDGWSDDGKYSWVKSPTFYGKTVEVGPLANMLVKLAAGRE
                     STQNKLNEIVAIYQKLTGNTLEVAQLHSTLGRIIGRTVHCCELQDILQNQYSALITNI
                     GKGDHTTFVKPNIPATGEFKGVGFLEAPRGMLSHWMVIKDGIISNYQAVVPSTWNSGP
                     RNFNDDVGPYEQSLVGTPVADPNKPLEVVRTIHSFDPCMACAVHVVDADGNEVVSVKV
                     L"
     gene            complement(3282..4460)
                     /gene="hybB"
                     /locus_tag="IRB70_002439"
     CDS             complement(3282..4460)
                     /gene="hybB"
                     /locus_tag="IRB70_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni/Fe-hydrogenase cytochrome b subunit"
                     /protein_id="HBC0632344.1"
                     /translation="MSHDPQPLGGKIISKPVMIFGPLIVICMLLIVKRLVFGLGSVSD
                     LNGGFPWGVWIAFDLLIGTGFACGGWALAWAVYVFNRGQYHPLVRPALLASLFGYSLG
                     GLSITIDVGRYWNLPYFYIPGHFNVNSVLFETAVCMTIYIGVMALEFAPALFERLGWK
                     VSLQRLNKVMFFIIALGALLPTMHQSSMGSLMISAGYKVHPLWQSYEMLPLFSLLTAF
                     IMGFSIVIFEGSLVQAGLRGNGPDEKSLFVKLTNTISVLLAIFIVLRFGELIYRDKLS
                     LAFAGDFYSVMFWIEVLLMLFPLVVLRVAKLRNDSRMLFLSALSALLGCATWRLTYSL
                     VAFNPGGGYAYFPTWEELLISIGFVAIEICAYIVLIRLLPILPPLKQNDHNRHEASKA
                     "
     gene            complement(4450..5436)
                     /gene="hybA"
                     /locus_tag="IRB70_002440"
     CDS             complement(4450..5436)
                     /gene="hybA"
                     /locus_tag="IRB70_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 operon protein HybA"
                     /protein_id="HBC0632345.1"
                     /translation="MNRRNFIKAASCGALLTGALPSVSHAAAENRPPIPGSLGMLYDS
                     TLCVGCQACVTKCQDINFPERNPQGEQTWSNNDKLSPYTNNIIQVWTSGTGVNKDQEE
                     NGYAYIKKQCMHCVDPNCVSVCPVSALKKDPKTGIVHYDKDVCTGCRYCMVACPYNVP
                     KYDYNNPFGALHKCELCNQKGVERLDKGGLPGCVEVCPAGAVIFGTREELMAEAKKRL
                     ALKPGSEYHYPRQTLKSGDTYLHTVPKYYPHLYGEKEGGGTQVLVLTGVPYENLDLPK
                     LDDLSTGARSEHVQHTLYKGMMLPLAVLAGLTVLVRRNTKNDHHDGGDDHES"
     gene            complement(5439..6557)
                     /gene="hybO"
                     /locus_tag="IRB70_002441"
     CDS             complement(5439..6557)
                     /gene="hybO"
                     /locus_tag="IRB70_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogenase 2 small subunit"
                     /protein_id="HBC0632346.1"
                     /translation="MTGDNTLIHSHGINRRDFMKLCAALAATMGLSSKAAAEMAESVT
                     NPQRPPVIWIGAQECTGCTESLLRATHPTVENLVLETISLEYHEVLSAAFGHQVEENK
                     HNALEKYKGQYVLVVDGSIPLKDNGIYCMVAGEPIVDHIRKAAEGAAAIIAIGSCSAW
                     GGVAAAGVNPTGAVSLQEVLPGKTVINIPGCPPNPHNFLATVAHIITYGKPPKLDDKN
                     RPTFAYGRLIHEHCERRPHFDAGRFAKEFGDEGHREGWCLYHLGCKGPETYGNCSTLQ
                     FCDVGGVWPVAIGHPCYGCNEEGIGFHKGIHQLANVENQTPRSQKPDVNAKEGGNVSA
                     GAIGLLGGVVGLVAGVSVMAVRELGRQQKKDNADSRGE"
     gene            complement(6746..7033)
                     /locus_tag="IRB70_002442"
     CDS             complement(6746..7033)
                     /locus_tag="IRB70_002442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2623 domain-containing protein"
                     /protein_id="HBC0632347.1"
                     /translation="MNNHFGKGLMAGLKATHADSAVNVTKYCADYKRGFVLGYSHRMY
                     EKTGDRQLSAWEAGILTRRYGLDKEMVMDFFRENNSCSTLRFFMAGYRLEN"
     gene            complement(7152..8039)
                     /locus_tag="IRB70_002443"
     CDS             complement(7152..8039)
                     /locus_tag="IRB70_002443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311911.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dienelactone hydrolase family protein"
                     /protein_id="HBC0632348.1"
                     /translation="MPRLTAKDFPQELLDYYDYYAHGKISKREFLNLAAKYAVGGMTA
                     LALFDLLKPNYALATQVEFTDPEIVAEYITYSSPNGHGEVRGYLVKPAKMSGKTPAVV
                     VVHENRGLNPYIEDVARRVAKAGYIALAPDGLSSVGGYPGNDDKGRELQQQVDPTKLM
                     NDFFAAIEFMQRYPQATGKVGITGFCYGGGVSNAAAVAYPELACAVPFYGRQAPTADV
                     AKIEAPLLLHYAELDTRINEGWPAYEAALKANNKVYEAYIYPGVNHGFHNDSTPRYDK
                     SAADLAWQRTLKWFDKYLS"
     gene            8195..9235
                     /gene="gpr"
                     /locus_tag="IRB70_002444"
     CDS             8195..9235
                     /gene="gpr"
                     /locus_tag="IRB70_002444"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-glyceraldehyde 3-phosphate reductase"
                     /protein_id="HBC0632349.1"
                     /translation="MVWLANPERYGQMQYRYCGKSGLRLPALSLGLWHNFGHVNAMES
                     QRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRLLREDFAAYRDELIISTKAGYDM
                     WPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSHRVDENTPMEETASALAHAVQSG
                     KALYVGISSYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVG
                     CIAFTPLAQGLLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQ
                     RGQSMAQMALSWLLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTEELAQIDQHIAD
                     GELNLWQASSDK"
     gene            complement(9275..9769)
                     /locus_tag="IRB70_002445"
     CDS             complement(9275..9769)
                     /locus_tag="IRB70_002445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00645 family protein"
                     /protein_id="HBC0632350.1"
                     /translation="MERFLENAMYASRWLLAPVYFGLSLALVALALKFFQEIIHVLPN
                     IFSMAESDLILVLLSLVDMTLVGGLLVMVMFSGYENFVSQLDISENKEKLNWLGKMDA
                     TSLKNKVAASIVAISSIHLLRVFMDAKNVPDNKLMWYVIIHLTFVLSAFVMGYLDRLT
                     RHNH"
     gene            9960..10844
                     /gene="yghA"
                     /locus_tag="IRB70_002446"
     CDS             9960..10844
                     /gene="yghA"
                     /locus_tag="IRB70_002446"
                     /EC_number="1.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HBC0632351.1"
                     /translation="MSHLKDPTTQYYTGEYPKQKQPTPGIQAKMTPVPDCGEKTYVGS
                     GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAISYLPVEEEDAQDVKKIIEECGRKA
                     VLLPGDLSDEKFARSLVHEAHKALGGLDIMALVAGKQVAIPDIADLTSEQFQKTFAIN
                     VFALFWLTQEALPLLPKGASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA
                     EKGIRVNIVAPGPIWTALQISGGQTQDKIPQFGQKTPMKRAGQPAELAPVYVYLASQE
                     SSYVTAEVHGVCGGEHLG"
     gene            complement(10883..11308)
                     /gene="exbD"
                     /locus_tag="IRB70_002447"
     CDS             complement(10883..11308)
                     /gene="exbD"
                     /locus_tag="IRB70_002447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein ExbD"
                     /protein_id="HBC0632352.1"
                     /translation="MAMHLNENLDDNGEMHDINVTPFIDVMLVLLIIFMVAAPLATVD
                     VKVNLPASTSTPQPRPEKPVYLSVKADNSMFIGNDPVTDETMVTALNALTEGKKDTTI
                     FFRADKTVDYETLMKVMDTLHQAGYLKIGLVGEETAKAK"
     gene            complement(11315..12049)
                     /gene="exbB"
                     /locus_tag="IRB70_002448"
     CDS             complement(11315..12049)
                     /gene="exbB"
                     /locus_tag="IRB70_002448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
                     /protein_id="HBC0632353.1"
                     /translation="MGNNLMQTDLSVWGMYQHADIVVKCVMIGLILASVVTWAIFFSK
                     SVEFFNQKRRLKREQQLLAEARSLNQANDIAADFGSKSLSLHLLNEAQNELELSEGSD
                     DNEGIKERTSFRLERRVAAVGRQMGRGNGYLATIGAISPFVGLFGTVWGIMNSFIGIA
                     QTQTTNLAVVAPGIAEALLATAIGLVAAIPAVVIYNVFARQIGGFKAMLGDVAAQVLL
                     LQSRDLDLEASAAAHPVRVAQKLRAG"
     gene            12301..13488
                     /gene="metC"
                     /locus_tag="IRB70_002449"
     CDS             12301..13488
                     /gene="metC"
                     /locus_tag="IRB70_002449"
                     /EC_number="4.4.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine beta-lyase"
                     /protein_id="HBC0632354.1"
                     /translation="MADKKLDTQLVNAGRSKKYTLGAVNSVIQRASSLVFDSVEAKKH
                     ATRNRANGELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFVEQGD
                     HVLMTNTAYEPSQDFCSKILSKLGVTTSWFDPLIGADIVKHVQPNTKIVFLESPGSIT
                     MEIHDVPAIVAAVRNVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDA
                     MIGTAVCNARCWEQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEW
                     LAGHPQVARVNHPALPGSKGHEFWKRDFTGSSGLFSFVLKKKLNDEELANYLDNFSLF
                     SMAYSWGGYESLILANQPEHIAAIRPQGEIDFSGTLIRLHIGLEDVDDLIADLDAGFA
                     RIV"
     gene            13628..14287
                     /locus_tag="IRB70_002450"
     CDS             13628..14287
                     /locus_tag="IRB70_002450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBC0632355.1"
                     /translation="MAVIQDIIAALWQHDFAALADPHIVSVVYFVMFATLFLENGLLP
                     ASFLPGDSLLILAGALIAQGVMDFLPTIAILTAAASLGCWLSYIQGRWLGNTKTVKGW
                     LAQLPAKYHQRATCMFDRHGLLALLAGRFLAFVRTLLPTMAGISGLPNRRFQFFNWLS
                     GLLWVSVVTSFGYALSMIPFVKRHEDQVMTFLMILPIALLTAGLLGTLFVVIKKKYCN
                     A"
     gene            complement(14327..15226)
                     /gene="yqhC"
                     /locus_tag="IRB70_002451"
     CDS             complement(14327..15226)
                     /gene="yqhC"
                     /locus_tag="IRB70_002451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001407451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YqhC"
                     /protein_id="HBC0632356.1"
                     /translation="MKREEICRLLADKVNKLKNKENELSELLPDVRLLYGETPFARTP
                     VMYEPGIIILFSGHKIGYINERVFRYDANEYLLLTVPLPFECETYATSEVPLAGLRLN
                     VDILQLQELLMDIGEDEHFQPSMAASGINSATLSEEILCAAERLLDVMERPLDARILG
                     KQIIREILYYVLTGPCGGALLALVSRQTHFSLISRVLKRIENKYTENLSVEQLAAEAN
                     MSVSAFHHNFKSVTSTSPLQYLKNYRLHKARMMIIHDGMKASAAAMRVGYESASQFSR
                     EFKRYFGVTPGEDAARMRAMQGN"
     gene            15420..16583
                     /gene="yqhD"
                     /locus_tag="IRB70_002452"
     CDS             15420..16583
                     /gene="yqhD"
                     /locus_tag="IRB70_002452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBC0632357.1"
                     /translation="MNNFNLHTPTRILFGKGAIAGLREQIPHDARVLITYGGGSVKKT
                     GVLDQVLDALKGMDVLEFGGIEPNPAYETLMNAVKLVREQKVTFLLAVGGGSVLDGTK
                     FIAAAANYPENIDPWHILQTGGKEIKSAIPMGCVLTLPATGSESNAGAVISRKTTGDK
                     QAFHSAHVQPVFAVLDPVYTYTLPPRQVANGVVDAFVHTVEQYVTKPVDAKIQDRFAE
                     GILLTLIEDGPKALKEPENYDVRANVMWAATQALNGLIGAGVPQDWATHMLGHELTAM
                     HGLDHAQTLAIVLPALWNEKRDTKRAKLLQYAERVWNITEGSDDERIDAAIAATRNFF
                     EQLGVPTHLSDYGLDGSSIPALLKKLEEHGMTQLGENHDITLDVSRRIYEAAR"
     gene            16688..17515
                     /gene="dkgA"
                     /locus_tag="IRB70_002453"
     CDS             16688..17515
                     /gene="dkgA"
                     /locus_tag="IRB70_002453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417485.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgA"
                     /protein_id="HBC0632358.1"
                     /translation="MANPTVIKLQDGNVMPQLGLGVWQASNEEVITAIQKALDVGYRS
                     IDTAAAYKNEEGVGKALKNASINREELFITTKLWNDDHKRPREALLDSLKKLQLDYID
                     LYLMHWPVPAIDHYVEAWKGMIELQKEGLIKSIGVCNFQIHHLQRLIDETGVTPVINQ
                     IELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYGKTPAQIVI
                     RWHLDSGLVVIPKSVTPSRIVENFDVWDFRLDKDELGEIAKLDQGKRLGPDPDQFGG"
     gene            17715..18641
                     /locus_tag="IRB70_002454"
     CDS             17715..18641
                     /locus_tag="IRB70_002454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708829.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbjP/YqhG family protein"
                     /protein_id="HBC0632359.1"
                     /translation="MKIILLFLAALASFTVHAQPPSQTVEQTVRQIYQNYKSDASTPY
                     FGETGERAITSARIQQALTLNDNLTLPGNIGWLDYDPVCDCQDFGDLVLESVAITQPD
                     ADHADAVVRFRIFKDDKEKTMQTLKMVAENGRWVIDDIVSNHGSVLQAVNSENEKTLA
                     AIASLQKEQPEAFVAELFEHIADYSWPWTWVVSDSYRQAVNAFYKTTFKTANNPDEDM
                     QIERQFIYDNPICFGEESLFSRVDEIRVLEKTADSARIHVRFTLTNGNNEEQELVLQR
                     REGKWKIADFIRPNSGSLLKQIEVKTAARLKQ"
     gene            18692..18949
                     /gene="yqhH"
                     /locus_tag="IRB70_002455"
     CDS             18692..18949
                     /gene="yqhH"
                     /locus_tag="IRB70_002455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein YqhH"
                     /protein_id="HBC0632360.1"
                     /translation="MKTIFTVGAVVLATCLLSGCVNEQKVNQLASNVQTLNAKIARLE
                     QDMKALRPQIYAAKSDANRANTRLDAQDYFDCLRCLRMYAE"
     gene            complement(18991..21210)
                     /locus_tag="IRB70_002456"
     CDS             complement(18991..21210)
                     /locus_tag="IRB70_002456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgiQ family radical SAM protein"
                     /protein_id="HBC0632361.1"
                     /translation="MSSISLIQPDRDLFSWPQYWAACFGPAPFLPMSREEMDQLGWDS
                     CDIILVTGDAYVDHPSFGMAICGRMLEAQGFRVGIIAQPDWSSKDDFMRLGKPNLFFG
                     VTAGNMDSMINRYTADRRLRHDDAYTPDNVAGKRPDRATLVYTQRCKEAWKDVPVILG
                     GIEASLRRTAHYDYWSDTVRRSVLVDSKADMLMFGNGERPLVEVAHRLAMGEPISEIR
                     DVRNTAIIVKEALPGWSGVDSTRLDTPGKIDPIPHPYGEDLPCADNKPVAPKKQEAKA
                     VTVQPPRPKPWEKTYVLLPSFEKVKGDKVLYAHASRILHHETNPGCARALMQKHGDRY
                     VWINPPAIPLSTEEMDSVFALPYKRVPHPAYGNARIPAYEMIRFSVNIMRGCFGGCSF
                     CSITEHEGRIIQSRSEDSIINEIEAIRDTVPGFTGVISDLGGPTANMYMLRCKSPRAE
                     QTCRRLSCVYPDICPHMDTNHEPTINLYRRARDLKGIKKILIASGVRYDIAVEDPRYI
                     KELATHHVGGYLKIAPEHTEEGPLSKMMKPGMGSYDRFKELFDTYSKQAGKEQYLIPY
                     FISAHPGTRDEDMVNLALWLKKHRFRLDQVQNFYPSPLANSTTMYYTGKNPLAKIGYK
                     SEDVFVPKGDKQRRLHKALLRYHDPANWPLIRQALEAMGKKHLIGSRRDCLVPAPTIE
                     EMREARRQNRNTRPALTKHTPMATQRQTPATAKKASSTQSRPVNAGAKKRPKAAVGR"
     gene            complement(21321..22733)
                     /gene="ftsP"
                     /locus_tag="IRB70_002457"
     CDS             complement(21321..22733)
                     /gene="ftsP"
                     /locus_tag="IRB70_002457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsP"
                     /protein_id="HBC0632362.1"
                     /translation="MSLSRRQFIQASGIALCAGAVPLKASAAGQQQPLPVPPLLESRR
                     GQPLFMTVQRAHWSFTPGTRASVWGINGRYLGPTIRVWKGDDVKLIYSNRLTENVSMT
                     VAGLQVPGPLMGGPARMMSPNADWAPVLPIRQNAATLWYHANTPNRTAQQVYNGLAGM
                     WLVEDEVSKSLPIPNHYGVDDFPVIIQDKRLDNFGTPEYNEPGSGGFVGDTLLVNGVQ
                     SPYVEVSRGWVRLRLLNASNSRRYQLQMSDGRPLHVISGDQGFLPAPVSVKQLSLAPG
                     ERREILVDMSNGDEVSITCGEAASIVDRIRGFFEPSSILVSTLVLTLRPTGLLPLVTD
                     SLPMRLLPTEIMAGSPIRSRDISLGDDPGINGQLWDVNRIDVTAQQGTWERWTVRADE
                     PQAFHIEGVMFQIRNVNGAMPFPEDRGWKDTVWVDGQVELLVYFGQPSWAHFPFYFNS
                     QTLEMADRGSIGQLLVNPVP"
     gene            complement(22808..23545)
                     /gene="plsC"
                     /locus_tag="IRB70_002458"
                     /gene_synonym="parF"
     CDS             complement(22808..23545)
                     /gene="plsC"
                     /locus_tag="IRB70_002458"
                     /gene_synonym="parF"
                     /EC_number="2.3.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acylglycerol-3-phosphate O-acyltransferase"
                     /protein_id="HBC0632363.1"
                     /translation="MLYIFRLIITVIYSILVCVFGSIYCLFSPRNPKHVATFGHMFGR
                     LAPLFGLKVECRKPADAESYGNAIYIANHQNNYDMVTASNIVQPPTVTVGKKSLLWIP
                     FFGQLYWLTGNLLIDRNNRTKAHGTIAEVVNHFKKRRISIWMFPEGTRSRGRGLLPFK
                     TGAFHAAIAAGVPIIPVCVSTTSNKINLNRLHNGLVIVEMLPPIDVSQYGKDQVRELA
                     AHCRSIMEQKIAELDKEVAEREAAGKV"
     gene            complement(23779..26037)
                     /gene="parC"
                     /locus_tag="IRB70_002459"
     CDS             complement(23779..26037)
                     /gene="parC"
                     /locus_tag="IRB70_002459"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBC0632364.1"
                     /translation="MSDMAERLALHEFTENAYLNYSMYVIMDRALPFIGDGLKPVQRR
                     IVYAMSELGLNASAKFKKSARTVGDVLGKYHPHGDIACYEAMVLMAQPFSYRYPLVDG
                     QGNWGAPDDPKSFAAMRYTESRLSKYSELLLSELGQGTADWVPNFDGTLQEPKMLPAR
                     LPNILLNGTTGIAVGMATDIPPHNLREVAQAAIALIDQPKTTLDQLLDIVQGPDYPTE
                     AEIITSRAEIRKIYENGRGSVRMRAVWKKEDGAVVISALPHQVSGARVLEQIAAQMRN
                     KKLPMVDDLRDESDHENPTRLVIVPRSNRVDMDQVMNHLFATTDLEKSYRINLNMIGL
                     DGRPAVKNLLEILSEWLVFRRDTVRRRLNYRLEKVLKRLHILEGLLVAFLNIDEVIEI
                     IRNEDEPKPALMSRFGLTETQAEAILELKLRHLAKLEEMKIRGEQSELEKERDQLQGI
                     LASERKMNNLLKKELQADAQAYGDERRSPLQEREEAKAMSEHDMLPSEPVTIVLSQMG
                     WVRSAKGHDIDAPGLNYKAGDSFKAAVKGKSNQPVVFVDSTGRSYAIDPITLPSARGQ
                     GEPLTGKLTLPPGATVDHMLMESDDQKLLMASDAGYGFVCTFNDLVARNRAGKALITL
                     PENAHVMPPVVIEDASDMLLAITQAGRMLMFPVSDLPQLSKGKGNKIINIPSAEAARG
                     EDGLAQLYVLPPQSTLTIHVGKRKIKLRPEELQKVTGERGRRGTLMRGLQRIDRVEID
                     SPRRASSGDSEE"
     gene            complement(26175..27782)
                     /locus_tag="IRB70_002460"
     CDS             complement(26175..27782)
                     /locus_tag="IRB70_002460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBC0632365.1"
                     /translation="MYTRNLLWLVSLVSAAPLYAADVPANTPLAPQQVFRYNNHSDPG
                     TLDPQKVEENTAAQIVLDLFEGLVWMDGEGQVQPAQAECWEILDGGKRYIFHLRSGLQ
                     WSDGQPLTAEDFVLGWQRAVDPKTASPFAGYLAQAHINNAAAIVAGKADVTSLGVKAM
                     DDRTLEVTLEQPVPWFTTMLAWPTLFPVPHHVIAKHGDSWSKPENMVYNGAFVLDQWV
                     VNEKITARKNPKYRDAQHTVLQQVEYLALDNSVTGYNRYRAGEVDLTWVPAQQIPAIE
                     KSLPGELRIIPRLNSEYYNFNLEKPPFNDVRVRRALYLTVDRQLIAQKVLGLRTPATT
                     LTPPEVKGFSATTFDELQKPMSERVAMAKVLLKQAGYDASHPLRFELFYNKYDLHEKT
                     AIALSSEWKKWLGAQVTLRTMEWKTYLDARRAGDFMLSRQSWDATYNDASTFLNTLKS
                     DSEENVGHWKNAQYDTLLNQAAQTADATKRNALYQQAEVIINQQAPLIPVYYQPLIKL
                     LKPYVGGFPLHNPQDYVYSKELYIKAH"
     gene            complement(27891..28373)
                     /locus_tag="IRB70_002461"
     CDS             complement(27891..28373)
                     /locus_tag="IRB70_002461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBC0632366.1"
                     /translation="MTNLTLDVNIIDFPSIPVAMLPHRCSPELLNYSVAKFIMWRKET
                     GLSPVNQSQTFGVAWDDPATTAPEAFRFDICGSVSEPIPDNRYGVSNGELTGGRYAVA
                     RHVGELDDISHTIWGIIRHWLPASGEKMRKAPILFHYTNLAEGMTEQRLETDVYVPLA
                     "
     gene            complement(28426..28818)
                     /gene="ygiW"
                     /locus_tag="IRB70_002462"
     CDS             complement(28426..28818)
                     /gene="ygiW"
                     /locus_tag="IRB70_002462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OB fold stress tolerance protein YgiW"
                     /protein_id="HBC0632367.1"
                     /translation="MKKFAAVIAVMALCSAPVMAAEQGGFSGPSATQSQAGGFQGPNG
                     SVTTVESAKSLRDDTWVTLRGNIVERISDDLYVFKDASGTINVDIDHKRWNGVTVTPK
                     DTVEIQGEVDKDWNSVEIDVKQIRKVNP"
     gene            28970..29629
                     /gene="qseB"
                     /locus_tag="IRB70_002463"
     CDS             28970..29629
                     /gene="qseB"
                     /locus_tag="IRB70_002463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator QseB"
                     /protein_id="HBC0632368.1"
                     /translation="MRILLIEDDMLIGDGIKTGLSKMGFSVDWFTQGRQGKEALYSAP
                     YDAVILDLTLPGMDGRDILREWREKGQREPVLILTARDALAERVEGLRLGADDYLCKP
                     FALIEVAARLEALMRRTNGQASNELRHGNVMLDPGKRIATLAGEPLTLKPKEFALLEL
                     LMRNAGRVLPRKLIEEKLYTWDEEVTSNAVEVHVHHLRRKLGSDFIRTVHGIGYTLGE
                     K"
     gene            29626..30975
                     /gene="qseC"
                     /locus_tag="IRB70_002464"
     CDS             29626..30975
                     /gene="qseC"
                     /locus_tag="IRB70_002464"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     QseC"
                     /protein_id="HBC0632369.1"
                     /translation="MKFTQRLSLRVRLTLIFLILASVTWLFSSFVAWKQTTDNVDELF
                     DTQLMLFAKRLSTLDLNEINAADRMAQTPNKLKHGHVDDDALTFAIFTHDGRMVLNDG
                     DNGEDIPYSYQREGFADGQLVGEDDPWRFVWMTSPDGKYRIVVGQEWEYREDMALAIV
                     AGQLIPWLVALPIMLIIMMVLLGRELAPLNKLALALRMRDPDSEKPLNATGVPSEVRP
                     LVESLNQLFARTHAMMVRERRFTSDAAHELRSPLTALKVQTEVAQLSDDDPQARKKAL
                     LQLHSGIDRATRLVDQLLTLSRLDSLDNLQDVAEIPLEDLLQSSVMDIYHTAQQAKID
                     VRLTLNAHGIKRTGQPLLLSLLVRNLLDNAVRYSPQGCVVDVTLNADNFIVKDNGPGV
                     TPEALARIGERFYRPPGQTATGSGLGLSIVQRIAKLHGMNVEFGNAEQGGFEAKVSW"
     gene            complement(31021..31353)
                     /locus_tag="IRB70_002465"
     CDS             complement(31021..31353)
                     /locus_tag="IRB70_002465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2645 family protein"
                     /protein_id="HBC0632370.1"
                     /translation="MLKHKIQTIFEALLYIMLTYWLIDAFFAFNKYDWMLESGDNICS
                     IPSVSGEDRILQAMIAAFFLLTPLIILILRKLFMREMFEFWLYVFSLVICLGCGWWLF
                     WGRFIFCY"
     gene            31711..32292
                     /gene="mdaB"
                     /locus_tag="IRB70_002466"
     CDS             31711..32292
                     /gene="mdaB"
                     /locus_tag="IRB70_002466"
                     /EC_number="1.6.5.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH:quinone oxidoreductase MdaB"
                     /protein_id="HBC0632371.1"
                     /translation="MSNILIINGAKKFAHSNGQLNDTLTEVADGTLRDLGHDVRIVRA
                     DSDYDVKAEVQNFLWADVVIWQMPGWWMGAPWTVKKYIDDVFTEGHGTLYASDGRTRK
                     DPSKKYGSGGLVQGKKYMLSLTWNAPMEAFTEKDQFFHGVGVDGVYLPFHKANQFLGM
                     EPLPTFIANDVIKMPDVPRYTEEYRKHLVEIFG"
     gene            32323..32637
                     /locus_tag="IRB70_002467"
     CDS             32323..32637
                     /locus_tag="IRB70_002467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBC0632372.1"
                     /translation="MITVIAEIRTRPGQHHRQAVLDQFAKIVPTVLKEEGCHGYAPMV
                     DCAAGVSFQSMAPDSIVMIEQWESIAHLEAHLQTPHMKAYSEAVKGDVLEMNIRILQP
                     GL"
     gene            complement(32682..33569)
                     /locus_tag="IRB70_002468"
     CDS             complement(32682..33569)
                     /locus_tag="IRB70_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBC0632373.1"
                     /translation="MIQKDKVRVDIFGERFRTRASQLTPGLRVVASYINEHREVVLEQ
                     TAMEIAATLNTSDATVIRAIQALGFAGLRDLKRTLEQWLGPALSSSEKMSTTVSNLTS
                     DVNTAIDFVLEGHLYTCNVLSEPENRHALAQAVALLVQARQVAIFGIGASGILADYTA
                     RLFNRIGLPATALNRTGIGLAEQLIALQRGDVLIMMAQKSAHREGLTTLREARRLGIP
                     VILLTNALDSRFSKDASIVIHVPRGDEKGKTPLHGTVLLCLEMIVWSVASAVPQRAVK
                     TIKRINDFHRGLKTGRKNG"
     gene            complement(33566..34513)
                     /locus_tag="IRB70_002469"
     CDS             complement(33566..34513)
                     /locus_tag="IRB70_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-siderophore ABC transporter
                     substrate-binding protein"
                     /protein_id="HBC0632374.1"
                     /translation="MRLFFSLLILLSFFSRATEPVQVFTDDLGRKVTVPAHPKRIVSL
                     HDLDITIPLIELGVPPVASHGRTRPDGSHFIRSGALLTGVDFDNSSIAFIGTADIDIE
                     AIVAAKPDLIITEPTRNTPIEQLEKIAPTVSIDHLKGGAPEIYRKLAELTGTQSQLAI
                     LERRYQAQINALKATLDSQKITVSVIQANQGKINVMHSYHSLGRVLRDAGFRFPPLIE
                     SIPEGGRMDVSAERLPELDADFVFATWRGDTGGKPQDELAAMEKVMPGWCQFLTACRS
                     GRYVLISREEAISNSFASLGLMAAQIQSQIAGRPLPEDK"
     gene            complement(34524..35561)
                     /locus_tag="IRB70_002470"
     CDS             complement(34524..35561)
                     /locus_tag="IRB70_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311941.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBC0632375.1"
                     /translation="MNVGLRPLRVGKFSTLVRPKNLLLLGGLFLFAVGILIFGLMHGS
                     FSVPASEVGRALFSPENVSTDARYIVQDIRLPRVIMALLCGAMLGMAGAAMQSIARNG
                     LADPGLIGVKEGCSVAVLWLIFQFPMLGVFWRPVAGLAGGLLVALIVIFCARDISRPR
                     FVLIGIGVSWFFAAGIGVFMTTADVRDVQTALMWLSGSLHAANWMLVGISACWMLPAA
                     LLLLFTARTADIALLGHQVATGLGVNSSRLALLRVAAPIILTAVCVSCVGNIGFVGLI
                     APHISRFILRGGQTTLLLGSAVSGALLVILADSIGRLAFLPLQLPAGIIISLIGGPFF
                     LLLLWQRRNSF"
     gene            complement(35570..36553)
                     /locus_tag="IRB70_002471"
     CDS             complement(35570..36553)
                     /locus_tag="IRB70_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBC0632376.1"
                     /translation="MMRTGLVTVIFLALLLVGCVVYPGIGARFIAPQTVLQAFLHFDP
                     QNFDHNVIVRLRLPRLAAALLTGASLGVAGALLQAVIRNPLGEPHILGLNAGAALAVV
                     AASALGLAFPVGRPLLASTGGALLFLLILLLSSAGRSGLTPMKVTLCGVALSAFVSSI
                     TAAILILDEQKLLAMRTWLAGDLAGQDWATLGTSAWFSLGGFVLALYLAPSLNMLALG
                     DRMAQGLGVSVFRTRTFTLLAIALLCGAAVSIAGPIGFVGLLVPQIVRRLVSADLRVL
                     LPLSACVGALLLLLADIIARTLFTPHELATGVMTALVGAPVFVIMATRMFK"
     gene            complement(36550..37359)
                     /locus_tag="IRB70_002472"
     CDS             complement(36550..37359)
                     /locus_tag="IRB70_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0632377.1"
                     /translation="MAHNAKGQGLILDNVSAGYHKKIIVDGVSFSVPTEKMTVLVGAN
                     GCGKSTLLSTIARILQPMGGSILLDGKAIHEQPTKALSRRLGILPQSPLLPEGLTVYE
                     LVSRGRFPWQNFIRQWSDADELAVEEALKLTGTQEFAHLPVEKLSGGQRQRCWIAMVL
                     AQKTPYILLDEPTTWLDLRYQVEILELLHDLTRHHGRTVVVVLHDLNFAVNYGDTLIF
                     LRQGKVVRVLNEGEHCTPELVKAVFDVDVHASINPLTGKPFFMPFRGVEKV"
BASE COUNT         9452 a        10046 c         9312 g         8664 t
ORIGIN      
        1 aaagctaatc atcacgcgct ggtaatgtcg taatccattt ggcgcagcgc gtctaatgtg
       61 gctttggctt catcttcgtc gatgatgctc atggcaaatc cgacgtgtac cagcacccac
      121 tggcccagca gatcggcagg gttaccttca caaatcaggg cgatattcac gtcgcgcttg
      181 ataccacata cttcaacctg cgcaagctgg tgaatatctt caccgacagc cagcacctgg
      241 cctggaacgc caatacacat tgttaactcc ggttattcaa cttcaatact tttgacgatc
      301 agcgaatcgc cggtatcgac acgcaaccgc tcgccatgac agagcggaca ctgcgcatcg
      361 tgctgatgaa tctccaccac ctggctgcaa tcccagcacc aggcctgggc gggtttatag
      421 acgatatgta aatcgcaccc ttgcgccacc gttccgtggc agacaatttc aaaactaaaa
      481 cggacggcgc tctcctcaac gcaggagagc gcgccaattt ccagccacac ggcggtgacg
      541 cgcttaacat cgtgctgctc cgcctgccgt tggataattt caacggcgct ctggcaaagc
      601 gacaactcat gcattttcgc cactcctgcg gccaaacagc agggcgcgac gccctgcgtg
      661 tggtacatcc ggattcgtga ctggcagcga aaggatcatt cgtgcgcagt catccgtcag
      721 gcgttggccc tcttcaatcg acatgctgtg cgaaagcggc gacatcagcg agcaggagag
      781 gtattgcgaa acaccgtcca gttcgccaac ggtaaaggtc atggtgccat acggcagttg
      841 cagaccaatt ttttcactca ctttgcgcag tggccagagt tgatccgggc cggggaagat
      901 aaccgcactc agcatccacg gggtgatcac acaccccgtc cactgacctt cgaacagcgt
      961 aaagtcagaa acatacaccg gcattgaagg atgcagaaaa gagagatcgt gcatcgaacg
     1021 ccgggcaatt tcttcaaacg ctgcctgtac ttgcgccttc ggggaggtct ggaaacctgc
     1081 tatctcttca gtcatgaatc gcctcccgtg ggatggcttc cacgcctgat tcgcgcagcg
     1141 cagccagaac atgctcaagc gcaggttcaa tcattgcttc aaccgtcggc gttaagccga
     1201 tgtgtggctc cagcgattcc gggatcacgc cgaccagggt cagctttttc ggaaactcac
     1261 cggtgaagcg cagggccgac aatacgtcgg ccaggccaag ctgatgcgga gagattttgt
     1321 tggtaaacaa cgccggaact tcttcatccc gcaggatcat catcgttccc ggcgcgctct
     1381 tcttcgacac aatggcatcc gcaatgatca gatgatcacg atttgccatg tcgccaagca
     1441 gctccattcc cgccgtgccg ccatcgagga tctcaacata atctggcaga atatatcgtt
     1501 gctctaacgc ttcgacaatc cgcacaccga tggcttcatc ggtcagcaaa atattgccaa
     1561 cccctaagac taaaatacgc attacagaac cttcactgaa accacttcgt tgccgtcggc
     1621 atccactacg tgtaccgcac aggccatgca cgggtcgaag gagtgaatgg tacgcaccac
     1681 ttccagcggt ttattcggat cggcaaccgg cgtacccacc agcgactgct cgtaaggacc
     1741 gacgtcatca ttgaagttac gcgggccaga gttccaggtt gatggaacaa ccgcctggta
     1801 gttgctgatg ataccgtctt taataaccat ccagtgagag agcataccgc gcggcgcttc
     1861 gaggaagcca acacctttga actcacccgt tgccggaatg ttcggtttca cgaaggtggt
     1921 gtgatcgcct ttgccgatat tggtgatcag tgcactgtat tggttttgca ggatatcctg
     1981 caattcgcag cagtgaacgg tacgaccaat aatacggccc agcgtggagt gcagctgcgc
     2041 cacttccagc gtgttgccag tcagtttctg ataaatcgca acgatttcat tcagtttatt
     2101 ctgggtagat tcgcgacctg ccgccagttt caccagcata ttagccagcg gacccacttc
     2161 taccgttttg ccgtagaaag tcggtgattt cacccaggaa tatttcccgt cgtcagacca
     2221 accatcataa gccggaatgg tggtaccttc ccacggtgcc tgcggcgctt cgtctttata
     2281 ccaggagtgc ttcgcgcttt cctgaatgcc tttgatcagg tattcatcgg agtgggaagt
     2341 gatcgggcga tacgaggaca gatccgcatt ctcaatgtag ccgcccggga acaggaagct
     2401 gccgtttttg ctgtcggtcg ggaattccgg cacgctcagg tagttcaccg cacctttacc
     2461 gcgcgtcagc cattccgggt agaacgcggc gataaccgcg gtatcaacct tataaacctg
     2521 ctcaacaaag tcgctcagct tgtcgatgaa ggacttgatg tacatcagac gctcaagatt
     2581 cagcacgccc agaccgtcga ggttgatcgg gttagcgacc ccacctactg ccaggttctg
     2641 aatgtgcggc gttttaccgc ccagcagcgc cacgacgcgg ttagcgtcac gctggcactc
     2701 cagcgcctgc aggtagtgcg ctaccgcaat caggttcact tccggcggca gtttcatcgc
     2761 cgggtgaccc cagtagccat tggcgaaaat acccaactga ccgctggcaa ccagatcttt
     2821 gatcttgttc tgaactttag tgaactcttc cggactgttc agatgccagg tcgaaacgcc
     2881 tttcagcatt tcggaggctt tggttgggtc agcttgcagt gcagaagtga tatccaccca
     2941 gtccagcgcc gaaagctgat agaaatgaac gatatggtca tgcgtggtgt gcgcagccag
     3001 aatgatgtta cggatgtatt gcgcgttaac cggaacgtcg atattcagcg cactctctgc
     3061 cgcacgaacg gaagacagcg cgtgagtagt cgtacatacg ccacagatac gttgcacaat
     3121 catccatgca tcgcgcggat cgcggttttt cacgatctct tccatgccgc gccacatggt
     3181 accggaagcc catgctttcg aaacgacgcc attttcgatt tcgcaatcga tgcgtaaatg
     3241 cccctcaata cgggttaccg gatcaatagt aattctctgg ctcatgcttt gctcgcctca
     3301 tgacgattat gatcgttttg ttttaaagga ggaagtatcg gcagtagacg aatgagtacg
     3361 atgtaagcgc aaatctcaat agccacaaaa ccaatagaaa tcaacagttc ttcccaggtc
     3421 gggaagtagg cgtaaccgcc gcccgggttg aatgccacca gcgaataggt cagacgccag
     3481 gttgcacaac ctaacagcgc gctcagtgct gacaggaaca gcatgcggga atcattacgc
     3541 agcttcgcca cacgcagaac gaccagcggg aagagcatca gcaggacttc aatccagaac
     3601 atcacggaat agaagtcacc ggcaaacgct aacgacagct tgtcgcgata gataagctcg
     3661 ccaaagcgca gcacgatgaa aatcgccagc aacacactga tggtgttggt cagcttaacg
     3721 aacagactct tttcatccgg accgttgcca cgcagacccg cctgcaccag cgaaccttca
     3781 aagatgacaa tcgagaagcc catgatgaac gccgtcagca gcgagaacag cggcaacatt
     3841 tcatagctct gccacaacgg atgcactttg tagcccgccg agatcatcag cgaccccatt
     3901 gaagactggt gcatagttgg cagcagcgca ccgagcgcga tgatgaagaa catcaccttg
     3961 ttcagacgct gtagcgacac cttccagccc aatcgttcaa acaatgccgg agcaaactcc
     4021 agtgccatca cgccgatgta gatggtcata cagaccgccg tctcgaacag taccgagttc
     4081 acgttgaagt gacccggaat gtagaagtac ggcaggttcc agtagcgacc aacgtcgatg
     4141 gtgatcgaca agccacccag tgagtaaccg aacagactcg ccaacagcgc cggacgcacc
     4201 agcggatggt attgcccacg gttaaagacg tataccgccc acgccagcgc ccagccgcca
     4261 caggcaaagc cggtgccgat caacaggtca aacgcgatcc acacacccca cgggaagccg
     4321 ccgttcaggt cagagactga gcccagaccg aacaccagac gcttcacaat caggagcata
     4381 cagatgacga ttaacggtcc aaaaatcatg accggtttac tgatgatttt gccgcccagc
     4441 ggttgtggat catgactcat gatcgtctcc tccgtcgtga tggtcgtttt tggtgttgcg
     4501 acgaaccagc acggttaagc ccgccagcac agccagtggt agcatcatgc ctttatacag
     4561 ggtgtgttgg acatgttcgg aacgcgcacc agtagaaaga tcgtccagtt tcggcaggtc
     4621 gagattttca taaggcacac cggtcagtac cagaacctga gtaccgccgc cctctttctc
     4681 gccgtacaga tgcggataat atttcggcac cgtatgcagg taagtgtcgc cagatttcag
     4741 cgtctgacgc ggatagtggt attcgctgcc tggcttcagc gccagacgtt ttttcgcctc
     4801 agccatcagc tcttcacgcg taccaaaaat caccgcgccc gccgggcaca cttctacgca
     4861 gccaggcaga ccgcctttat caagacgttc cacacctttc tggttgcaca gttcacactt
     4921 atgcagcgca ccaaatgggt tgttgtagtc gtacttcggc acgttgtatg ggcaggcgac
     4981 catgcagtaa cggcagccag tgcacacatc tttgtcgtaa tggacaatgc cggttttcgg
     5041 atcttttttc agcgcagaga ccggacacac ggagacacag ttcggatcga cgcagtgcat
     5101 acactgtttc ttaatgtacg cgtagccgtt ctcttcctgg tctttgttga cacccgtgcc
     5161 gctggtccac acctgaataa tgttattggt atacggcgac agtttgtcgt tgttcgacca
     5221 ggtctgttcc ccttgcgggt tacgttcagg gaagttgata tcctgacact tggtgacgca
     5281 agcctggcag cctacgcaca aggtcgagtc gtacaacatc cccagcgatc ccggaattgg
     5341 cgggcggttt tcagcagccg catgactgac agacggcagc gcgcccgtca gcaatgcccc
     5401 gcaggaggct gctttaataa aattacgtct gttcacggtt attctccccg tgagtcagcg
     5461 ttatctttct tttgctgacg acccagttca cgcaccgcca tcacgctgac accggcaacc
     5521 agcccaacca caccgccgag caaaccaata gcgcccgcag agacgttgcc gccttcttta
     5581 gcgttaacgt ccggtttctg tgaacgcgga gtctgatttt cgacgttggc aagctgatgg
     5641 atgcctttat ggaagccgat accttcttcg ttacagccat agcacgggtg accaatcgcc
     5701 accggccaca caccgccaac atcgcagaat tgcagcgttg agcagttgcc gtaagtttct
     5761 ggccctttac agccgaggtg gtacaggcac cagccttcac ggtggccttc gtcgccgaac
     5821 tctttcgcaa agcgaccagc atcgaagtgc gggcgacgtt cacagtgttc gtgaatcaga
     5881 cgaccgtagg cgaaagtcgg acggtttttg tcatccagct tcggtggttt gccgtaagtg
     5941 atgatgtgcg caacggtcgc gaggaagttg tgcgggttcg gcgggcagcc aggaatgttg
     6001 attacagttt tgcctggcag aacttcttgc agactgaccg cgccagttgg gttaacccca
     6061 gccgcggcaa caccgcccca cgcagagcag gaaccgatag cgataatggc tgctgcgcct
     6121 tccgccgctt tgcggatgtg atccacaatc ggctcaccgg caaccatgca ataaatacca
     6181 ttatctttta atgggatgga accatccacc actaacacat actgcccttt gtacttctcg
     6241 agagcgttat gtttgttctc ttcgacctga tgaccgaagg cggcggaaag cacttcgtga
     6301 tactccagag agatagtctc cagcacgagg ttttctaccg ttggatgcgt tgcacgaagc
     6361 agagattcag tacaaccggt acactcctgc gcgccaatcc agataactgg cggacgctgc
     6421 gggttagtaa ccgattcggc catctctgca gcggctttgc tacttaaccc catggtggcg
     6481 gctaatgctg cacaaagctt catgaaatca cgacggttaa tgccgtgaga atggatgagg
     6541 gtgttatctc cagtcattta tagttattcc gttgcgaaga cctggcatat attttgcctc
     6601 aatcgcaaaa tcaataatgc gatcgatgcg ccatttacca cacatttatt atggttatcg
     6661 atatcatgat actgcggcgg ggcgctaaaa cgaagggaag aagcattagt gtaattaatt
     6721 aaagcaagat aatacgtatg tttgatcaat tttcgaggcg ataaccggcc ataaaaaagc
     6781 gcaacgtaga acaggaatta ttctcacgaa agaaatccat taccatctct ttatccagtc
     6841 catagcggcg tgtcagaata cccgcttccc aggcgctaag ctggcgatct ccggtctttt
     6901 cgtacatccg gtgtgagtag cctaatacaa aaccgcgttt ataatcggca cagtattttg
     6961 tcacattaac cgcactgtcg gcatgcgttg cttttaatcc cgccattaag cctttaccaa
     7021 aatggttatt catcgttcac ctcattcgct atatattgtc atatatagcg atattttagg
     7081 caaagaacga cttttgcgca cgctattttt tcatgcttgt ttaagacgta atcccgtaag
     7141 agataaacct atcaggagag atatttatcg aaccatttca gcgtcctttg ccaggcaaga
     7201 tcggcggcag atttgtcata acggggcgtg gaatcattat ggaatccgtg attaactccc
     7261 ggatagatat acgcctcata gaccttatta ttggctttca acgccgcctc gtaagcaggc
     7321 cagccctcgt tgattcgggt gtccagttcc gcgtagtgga gtagtaaagg cgcttcaatc
     7381 ttcgccacat cggcggtggg tgcctgtcga ccataaaacg gcaccgcgca ggccagttcc
     7441 ggatacgcga cagccgccgc gttcgatacg ccaccgccat agcaaaatcc ggtaataccc
     7501 actttgcctg tcgcttgcgg atagcgttgc ataaactcaa ttgcggcaaa gaaatcattc
     7561 atcagtttgg ttggatcaac ctgctgttgc agctcacgac ctttatcatc attacccgga
     7621 taacctccaa cggaacttaa gccgtcaggt gccagggcga tataccccgc cttcgccact
     7681 cgccgtgcca catcttcgat atacggattc agtccacgat tctcatgcac caccactacg
     7741 gctggcgttt tgccgctcat ctttgcgggc ttcaccagat aaccccgcac ctcgccgtga
     7801 ccatttggtg aagaatacgt gatgtactca gcaacaattt ccgggtcggt aaactctacc
     7861 tgagtcgcca gcgcataatt tggcttgagc aaatcaaaca acgctaatgc cgtcatcccg
     7921 cctaccgcat acttcgccgc aaggttgagg aactcacgtt tcgaaatttt cccgtgagcg
     7981 taatagtcgt agtaatccag caactcttgt gggaaatctt tagcggtcag acgcggcatc
     8041 attgcactcc tcaattggtg tttttttaag caaagcataa gcacgtgttt ttgcccagtt
     8101 tttcgtcact ctgtgagcca gactacggga tacgcgctga tgaatcgcta aactagaaca
     8161 ttgtttcgaa attgaacggt ggaaaggaga ggtcatggtc tggttagcga atcccgagcg
     8221 ttacgggcag atgcagtacc gttattgcgg aaaaagcggt ttacgcctgc ccgcgttatc
     8281 gctcggttta tggcacaatt tcggtcacgt taacgcgatg gaatcacagc gtgcgatcct
     8341 gcgtaaagcg tttgatttag gcattacgca ctttgattta gccaacaatt acgggccgcc
     8401 tccaggaagc gcagaagaga actttggtcg cctgctgcgg gaggattttg ccgcttatcg
     8461 cgatgaactg attatctcta ccaaggctgg ctacgatatg tggcccggcc cttacggctc
     8521 tggcggttca cgtaaatacc tgctcgccag cctcgaccaa agcctgaagc gtatggggct
     8581 tgagtatgtc gatatctttt actctcatcg cgtcgatgaa aatacgccga tggaagaaac
     8641 cgcctctgcg ctggcccatg cggtacaaag cggtaaggcg ctgtatgtcg ggatctcctc
     8701 ttactcgcca gagcggacgc aaaaaatggt cgagttactg cgcgagtgga aaattccgct
     8761 gttaattcat caaccttcgt acaatttact gaaccgctgg gtggataaaa gcggcctgct
     8821 ggataccctg caaaataacg gcgtgggctg cattgccttt actcctctgg ctcagggatt
     8881 gctgaccggg aaatatctca acggcattcc gcaagattca cggatgcatc gtgaagggaa
     8941 taaagttcgt ggtctgacgc cgaaaatgct caccgaagcc aacctcaaca gcctgcggtt
     9001 attgaatgaa atggcacagc aacgtggaca atcaatggcg caaatggcgt taagctggtt
     9061 gctgaaagat gatcgcgtga cgtcggtatt gattggtgcc agccgcgcgg agcaacttga
     9121 ggagaacgtg caggcgctga ataatctgac atttagcacc gaggagctgg cgcagattga
     9181 tcagcatatc gccgatggcg agctgaatct gtggcaggcg tcttccgata aatgatctgt
     9241 taataacggg cgcgagaacc gcgcccgaat cagatcagtg attatgacga gtcagtcggt
     9301 caagatagcc catcacaaat gcagagagca caaacgtcag atggatgatg acgtaccaca
     9361 tcagtttgtt atcagggaca tttttcgcat ccataaagac gcgcagtaag tgaatggaag
     9421 aaattgccac aatcgacgct gctactttgt ttttcagcga cgttgcatcc attttcccca
     9481 gccagttcag cttctctttg ttctcggaga tatccagttg tgagacgaaa ttctcataac
     9541 cggaaaacat caccatcacc agcaaaccgc caaccagcgt catatccacc agcgacagca
     9601 acacgaggat caaatctgat tccgccatcg agaagatatt cggcagtacg tgaataatct
     9661 cctggaagaa cttcagcgcc agggcaacta acgccagcga aaggccaaag tacacggggg
     9721 caagcagcca gcgagaagca tacattgcat tttcaagaaa acgttccata cattcctgtc
     9781 gtgtagttaa aacgggcaac agtatatcgc aattgagtaa acagcacgca acagcaaatc
     9841 aacatatccg ttaaaccttt gtcgcataat tctgagggtt agggatcttc ctggttccct
     9901 tatcaacgca tcgagagcgt ctacccttaa aggacgttga acctgaaggg agaaaaatga
     9961 tgtctcattt aaaagacccg accacgcagt attacactgg tgaatatccc aaacagaaac
    10021 aaccgacgcc aggcatccag gcgaaaatga caccggtgcc ggattgcggc gagaaaacct
    10081 atgttggtag cggtcgcctg aaagatcgta aagcactggt gacagggggc gattccggaa
    10141 tcggtcgcgc tgccgccatc gcttacgcgc gtgaaggggc cgacgtggcg atcagttatc
    10201 ttcccgtgga agaagaagac gctcaggatg tgaaaaagat cattgaagaa tgcggacgca
    10261 aagccgtcct gctgccaggc gatttaagcg atgagaaatt tgcccgttcg ctggttcacg
    10321 aagcgcataa ggccttaggc gggctggata ttatggcgct ggtcgccggg aaacaggttg
    10381 ccattcctga tattgcagac ctcaccagcg aacagtttca aaagaccttt gccattaacg
    10441 ttttcgcgct gttctggcta acccaggaag cgctccccct gctaccgaaa ggtgctagta
    10501 tcatcaccac ttcgtcaatc caggcatacc agccaagccc gcatttactg gactatgcgg
    10561 ctacgaaggc ggcgattctg aactacagcc gtggcctggc aaaacaggtc gcagagaaag
    10621 gtattcgggt gaatattgtt gcgccaggcc cgatctggac agcactgcaa atttccggcg
    10681 gacagacgca ggataagatc ccgcagtttg gtcagaaaac gccgatgaag cgtgccgggc
    10741 aaccggcgga actggcccct gtatatgttt atctggcaag tcaggagtcg agctacgtga
    10801 ccgcagaagt gcatggcgtg tgcggcggcg agcatttagg ctaaaaaaat gcccggttgt
    10861 gaaaagcaac cgggcatcat ttttatttcg ctttggcagt ttcttcgccg accaggccta
    10921 tcttcaggta acccgcctga tgcagcgtat ccattacctt catcaacgtc tcgtaatcga
    10981 cggttttatc cgcacggaag aagatggtgg tgtctttctt accttcagtt aacgcattca
    11041 gcgccgtaac cattgtttca tcggtgaccg gatcgttacc gataaacatc gagttgtccg
    11101 ccttcaccga cagataaacc ggtttttccg ggcgcggctg cggcgtgctg gtagaagcag
    11161 gcaagttcac cttcacatct accgtcgcta acggtgccgc caccataaag ataatcagca
    11221 gaaccaacat cacgtcgata aacggcgtca cgttgatatc atgcatttcg ccgttatcgt
    11281 cgaggttttc gttaagatgc attgccatcg gacattatcc tgcgcgtaat ttttgtgcga
    11341 cacgaaccgg atgcgcagcg gcgctggctt ccagatccag gtcacggctt tgcagcaaca
    11401 atacctgcgc tgcaacatca cccagcatcg ctttaaagcc gccaatctgg cgtgcaaata
    11461 cgttatagat aacgaccgcc ggaatcgctg ccacgaggcc gattgccgtt gctaacagag
    11521 cttctgcaat acccggcgca acgactgcca ggttagtggt ctgcgtttgc gcgataccaa
    11581 taaagctgtt catgatgccc cagaccgtac caaagaggcc cacaaacggc gaaatcgcgc
    11641 cgatggttgc cagatagccg ttaccgcggc ccatttgacg acctactgcg gcgacccgac
    11701 gctccagacg gaagctggta cgttctttaa taccttcgtt atcgtcgctg ccttctgaca
    11761 gttccagctc attctgcgct tcattgagca aatgcaggct taagcttttg ctaccaaaat
    11821 cagcggcgat atcgttggcc tggtttaagg aacgcgcttc agccagcagt tgctgctcgc
    11881 gcttaaggcg acgcttctga ttgaagaact ctacgctctt actgaagaag attgcccagg
    11941 tgactacgga ggccaaaata agcccaatca tcacgcactt aacgacaata tcggcgtgct
    12001 gatacatacc ccagacggaa aggtccgtct gcattaaatt attacccact gtgtatctcc
    12061 aggacgcaag tcacaaaatc tgcgcataat aatatcaaaa cgacgtcgaa ttgatagtcg
    12121 ttctcattac tatttgcata ctgccgtacc tttgctttct tttccttgcg tttacgcagt
    12181 aaaaaagtca ccagcacgcc atttgcgaaa attttctgct ttatgccaat tcttcaggat
    12241 gcgcccgcga atattcatgc tagtttagac atccagacgt ataaaaacag gaatcccgag
    12301 atggcggaca aaaagcttga tactcaactg gtgaatgcag gacgcagcaa aaaatacact
    12361 ctcggcgcgg taaatagcgt gattcagcgc gcttcttcac tggtctttga cagtgtggaa
    12421 gccaaaaaac acgcaacgcg caatcgcgcc aatggcgagt tgttctatgg acggcgcgga
    12481 acgttaaccc atttctcctt acaacaagcg atgtgcgaac tggaaggtgg cgcaggctgc
    12541 gtgctgttcc cctgcggggc ggcggcggtt gctaattcta ttcttgcttt tgtcgaacag
    12601 ggcgatcatg tgttgatgac caacaccgcc tatgaaccga gtcaggattt ctgtagcaaa
    12661 atcctcagca aactgggcgt aacgacatcg tggtttgatc cgctgattgg cgcagatatc
    12721 gttaaacatg tgcagccaaa cactaaaatc gtgtttctgg aatccccagg ctccatcacc
    12781 atggaaatcc acgacgttcc ggcgattgtt gccgccgtgc gcaatgtggt gccagatgcc
    12841 atcattatga tcgataacac ctgggcggcc ggtgtgctgt ttaaggcgct ggattttggc
    12901 attgatgttt ccattcaggc cgctaccaaa tatctggtgg ggcattcaga tgcgatgatt
    12961 ggtactgccg tatgcaatgc ccgttgctgg gagcagctgc gggagaatgc ctatctgatg
    13021 ggccagatgg tcgatgccga taccgcctat ataaccagcc gtggcctgcg cactttgggt
    13081 gttcgcctgc gtcaacatca tgaaagcagt ctgaaagtgg ctgagtggct ggcaggacat
    13141 ccgcaagtag cgcgagttaa ccaccctgct ctgcctggca gtaaaggcca cgaattctgg
    13201 aaacgagact ttacaggtag cagcgggcta ttttcctttg tgcttaagaa aaagctcaat
    13261 gatgaagagc tggcgaacta tctggataac ttcagtttat tcagcatggc ctactcgtgg
    13321 ggcggttatg aatcgttgat cctggcaaat caaccagaac atatcgccgc cattcgcccg
    13381 caaggcgaga tcgattttag cgggaccttg attcgcctgc atattggtct ggaagatgtc
    13441 gacgatctga ttgccgatct ggacgccggt tttgcgcgaa ttgtataaca ttgccacttt
    13501 tggacaattt tgcagacatt ttattgtgaa aagtcttaaa ttgttgcgtc cgggatcaag
    13561 gcgtcccgga cgattcagga gtacaatagg cagataaagg cttaaacgct gttccacagg
    13621 aaagtccatg gctgttattc aagatatcat cgctgcgctc tggcaacacg actttgccgc
    13681 gctggcggat cctcatattg ttagcgttgt ttactttgtc atgtttgcca cgctgttttt
    13741 agaaaacggc ctgctgcccg cctcattttt gccaggcgac agcttgttga tattggctgg
    13801 cgcattgatt gcccaggggg ttatggattt tctgcctacg attgcgattc tgaccgccgc
    13861 agcaagtctg ggctgctggt taagttatat tcaggggcgc tggttaggga ataccaaaac
    13921 ggtgaaaggc tggctggcac agcttcctgc taaatatcac cagcgcgcca cctgcatgtt
    13981 tgaccgccac ggtctgctgg cgctgctggc tggacgtttt cttgcatttg tccgtacgct
    14041 gctgccaacc atggcaggaa tttccggttt gccaaaccgc cgtttccagt ttttcaactg
    14101 gttaagcgga ttgctgtggg tcagcgtggt aaccagtttc ggctatgcct taagtatgat
    14161 tccgttcgtt aaacgccatg aagatcaggt aatgacgttc ctgatgatcc tgccaattgc
    14221 cttgttaacc gctggcttgt taggcacgct gtttgtggtg attaaaaaaa aatactgtaa
    14281 cgcctgacga ttttccccgt tcccggttgc tgtaccggga acgtatttaa ttcccctgca
    14341 tcgcccgcat tcttgccgca tcttcccccg gcgtcacacc gaagtaacgt ttaaactcac
    14401 ggctaaattg cgatgcgctt tcatagccga cgcgcatcgc cgccgcgctg gctttcatgc
    14461 cgtcgtggat gatcatcatc cgcgccttat gcagacggta attcttcaaa tactgcaacg
    14521 gcgaggtgct agtgacagac ttaaaattat ggtggaacgc cgatacgctc atgttggctt
    14581 ctgccgccag ttgctcgacg ctcaggtttt cggtgtattt attctcaatc cgtttcagca
    14641 cgcggctaat caggctgaag tgagtctggc gactgaccag cgccagtaac gcgccgccgc
    14701 aaggtccggt cagcacgtag tacagaattt cgcggatgat ctgtttgccg agaatacgcg
    14761 catccagtgg tcgctccatc acgtcgagta accgctccgc cgcgcataaa atctcttctg
    14821 ataacgtggc ggagttaatc ccgctggctg ccatcgacgg ctggaaatgc tcatcttcgc
    14881 caatgtccat caacagttcc tgtaactgca aaatatcgac attgagacgc aaccctgcca
    14941 gcggcacctc tgacgtggca taggtttcgc actcaaacgg caacggcacc gtcagcagca
    15001 ggtattcatt ggcatcataa cgaaacacgc gttcattgat ataaccgatt ttatgcccgg
    15061 aaaagagaat tatgatgcca ggctcgtaca ttaccggtgt acgtgcgaaa ggcgtctcgc
    15121 catacaacaa acgcacatcg ggcaacagct ctgacaattc attttcttta tttttcagtt
    15181 tattaacttt atccgccagc aagcggcaaa tctcttcacg tttcatatcg cgtaatttct
    15241 taggaataat gcggcaattt gattgtgcgc aattttgtag catttctcca gcactctgga
    15301 gaaataggca agacattggc agaaatgagc attgagaggt acggcgctgg cgaccacaat
    15361 gaaaaacatc aggcagatcg ttctctgccc tcatattgac ccagcaaagg gagcaagtaa
    15421 tgaacaactt taatctgcac accccaaccc gcattctttt tggtaaaggc gcaatcgctg
    15481 gtttacgcga acaaattcct cacgatgctc gcgtattgat tacctacggc ggcggcagcg
    15541 tgaaaaaaac cggcgttctc gatcaagttc tggatgccct gaaaggcatg gacgtgctgg
    15601 aatttggcgg tattgagcca aacccggctt atgaaacgct gatgaacgcc gtgaaactgg
    15661 ttcgcgaaca aaaagtgact ttcctgctgg cggttggcgg cggttctgta ctggacggca
    15721 ccaaatttat cgccgcagcg gctaattatc cggaaaatat cgatccgtgg cacattctac
    15781 aaacgggcgg taaagaaatt aaaagcgcca tcccgatggg ctgtgtgctg acgctgccag
    15841 caaccggttc agaatccaac gcaggcgcgg tgatctcccg taaaaccaca ggcgacaagc
    15901 aggcattcca ttctgcccat gttcaacccg tatttgccgt gctcgatccg gtttatacct
    15961 acaccctgcc gccgcgtcag gtggctaacg gtgtagtgga cgcctttgta cacaccgtgg
    16021 aacagtatgt taccaaaccg gttgatgcca aaattcagga ccgtttcgca gaaggcattt
    16081 tgttgacgct gatcgaagat ggtccgaaag ccctgaaaga gccagaaaac tacgatgtgc
    16141 gcgccaacgt tatgtgggcg gcgactcagg cgctgaacgg tttgatcggc gctggcgtac
    16201 cgcaggactg ggcaacgcat atgctgggcc acgaactgac tgcgatgcac ggtctggatc
    16261 acgcacaaac actggctatc gtcctgcctg cactgtggaa tgaaaaacgc gataccaagc
    16321 gcgctaagct gctgcaatat gctgaacgcg tctggaacat cacagaaggt tccgacgatg
    16381 agcgtattga cgccgcgatt gccgcaaccc gcaatttctt tgagcaatta ggcgtgccga
    16441 cccacctctc cgactacggt ctggacggca gctccatccc ggctttgttg aaaaaactgg
    16501 aagagcacgg tatgacccaa ctgggcgaaa atcatgacat tacgctggat gtcagccgcc
    16561 gtatatacga agccgcccgc taagcttttt acgcctcaaa ctttcgtttt cgggcatttc
    16621 gtccagactt aagttcacaa cacctcaccg gagcctgctc cggtgagttc atataaagga
    16681 ggaacgtatg gctaatccaa ccgttattaa gctacaggat ggcaatgtca tgccccagct
    16741 gggactgggc gtctggcaag caagtaatga ggaagtaatc accgccattc aaaaagcgtt
    16801 agacgtgggt tatcgctcga ttgataccgc cgcggcctat aagaacgaag aaggtgtcgg
    16861 caaagccctg aaaaatgcct caatcaacag agaagaactg ttcatcacca ctaaactgtg
    16921 gaacgacgac cacaagcgcc cccgcgaagc cctgctcgac agcctgaaaa aactccagct
    16981 tgattatatc gacctctact taatgcactg gcccgttccc gctatcgacc attatgtcga
    17041 agcatggaaa ggcatgatcg aattgcaaaa agagggatta atcaaaagca tcggcgtgtg
    17101 caacttccag atccatcact tgcaacgcct gattgatgaa actggcgtga cgcctgtgat
    17161 aaaccagatc gaacttcacc cgctgatgca acaacgccag ctacatgcct ggaacgcgac
    17221 acacaaaatc cagaccgaat cctggagccc attagcgcaa ggagggaaag gcgttttcga
    17281 tcagaaagtc attcgcgatc tggcagataa atacggcaaa accccggcgc agattgttat
    17341 ccgctggcat ctggatagcg gcctggtggt gatcccgaaa tcggtcacac cttcacgcat
    17401 tgtcgaaaac tttgatgtct gggatttccg tctcgacaaa gacgaactcg gcgaaattgc
    17461 aaaactcgat cagggcaagc gtctcggtcc cgatcctgac cagtttggcg gctaacgtgc
    17521 aaattctccc ggtggcggta atgttccgct accggacttt tcagaaatca tttattcccc
    17581 tcgcgtcctg cccattgtta ctcttccttg ttcaggaatg ccaaatataa ggacatcatc
    17641 atgcagagcc ggaagctctt aaaggaacaa ttcatctaca cccgggataa acgcaacgga
    17701 gaggtgaaaa acagatgaaa ataatacttc tgtttttagc agccctggca agttttaccg
    17761 tacacgcgca gcctccttca cagaccgtag aacaaacagt ccggcagatt tatcagaact
    17821 ataaatcaga tgccagtacg ccttatttcg gtgaaaccgg agagcgggcg ataacttcag
    17881 cgcgtattca acaggcgctt accctgaacg acaatcttac gctgccgggc aatattggct
    17941 ggctggatta tgatccggtt tgtgattgtc aggattttgg cgatctggtg ttagaaagcg
    18001 tagcgataac ccaacctgac gccgatcatg ccgatgccgt tgtgcgcttt cgtatcttta
    18061 aagacgataa agaaaagacc atgcagacac tgaaaatggt ggcggaaaat ggtcgttggg
    18121 tcattgacga tattgtcagc aatcatggca gcgtcttaca agcagttaat agcgagaatg
    18181 aaaaaacgct ggccgctata gcttcgttgc aaaaagaaca gccggaagcc tttgttgccg
    18241 aactctttga acatattgct gattatagct ggccgtggac gtgggtggtt tccgactctt
    18301 accgccaggc ggtcaatgcc ttctataaaa ccaccttcaa gactgccaac aatcccgatg
    18361 aagatatgca aatagaacgg caatttattt acgacaatcc gatctgtttt ggcgaagagt
    18421 cgctattttc acgcgttgat gaaatccgtg tcctggagaa aaccgccgat tccgcccgca
    18481 ttcatgttcg ttttacgctg accaatggca acaacgaaga gcaagaactg gttttacagc
    18541 ggcgcgaagg taagtggaaa atcgctgatt ttatccgccc gaacagcggc agcctactta
    18601 agcagattga ggtaaaaacc gccgccagat taaagcaatg agctgaatta aataacaatt
    18661 agccggaaca ataaataaaa gggaacacta tatgaaaacg attttcaccg tgggagctgt
    18721 tgttctggca acctgcttgc tcagtggctg cgtcaatgag caaaaggtca atcagctggc
    18781 gagcaatgtg caaacattaa atgccaaaat cgcccggctt gagcaggata tgaaagcatt
    18841 acgcccacaa atctatgctg ccaaatccga cgctaacaga gccaatacgc gtcttgatgc
    18901 tcaggactat tttgattgcc tgcgctgctt gcgtatgtac gcagaatgat aaaaaaatcc
    18961 ccggcagcat tctgttaccg gggatatttt ttaacgtcca accgccgctt tagggcgttt
    19021 cttcgcacca gcattcaccg gacgagattg cgtagacgac gctttttttg ccgtagcagg
    19081 cgtctgacgc tgggtcgcca tcggcgtatg tttagtcaac gccggacggg tattgcggtt
    19141 ctggcgacga gcctcacgca tctcttcaat ggttggcgca ggcactaagc aatcgcgacg
    19201 gctgccaatc agatgctttt tgcccatcgc ttccagcgcc tgacggatta acggccagtt
    19261 tgccggatcg tggtaacgca acaacgcttt atgcaaacga cgctgcttgt cacccttcgg
    19321 tacaaagacg tcttcactct tataaccaat cttcgccagc gggtttttgc cggtgtaata
    19381 catagtggtc gagttagcca gcggcgatgg gtagaaattc tgtacctggt cgaggcggaa
    19441 acgatgcttt ttcagccaca gcgccagatt caccatatct tcatcccgcg taccggggtg
    19501 cgcagagatg aaatagggga tcagatactg ctctttacct gcctgtttcg agtaagtatc
    19561 gaacagctct ttaaagcggt catagctgcc catgcccggc ttcatcatct tcgataacgg
    19621 cccttcttcg gtatgttccg gggcaatctt cagataaccg ccgacgtgat gggtcgccag
    19681 ctctttgata tagcgcggat cttccacggc gatgtcataa cgtacgccgg aagcgatcag
    19741 gatcttttta atgcctttca gatcacgcgc acggcgatag aggttaatcg tcggttcgtg
    19801 gttagtgtcc atatgcggac aaatatccgg gtaaacacac gacaagcggc ggcaggtctg
    19861 ttcagcgcgt ggcgatttgc agcgcaacat atacatgttg gcagttggcc caccgagatc
    19921 ggaaattacg cccgtaaaac ctggaacagt gtcgcggatc gcttcgatct cattgatgat
    19981 cgaatcttcc gaacggctct gaataatgcg cccttcgtgc tcggtgatag aacagaaaga
    20041 gcagccgcca aagcagccac gcataatgtt gaccgagaaa cgaatcattt cgtaagccgg
    20101 aatacgggca ttgccatagg ccggatgcgg cacgcgcttg tacggcagcg caaaaacgct
    20161 gtccatctct tcggtagaaa gcgggatagc aggcgggttg atccacacat agcggtcgcc
    20221 gtgtttttgc atcaatgcgc gggcgcagcc tgggttagtt tcgtggtgca gaatacgcga
    20281 agcatgggcg tacagcactt tatcgccctt cactttctcg aaagaaggca gcaatacgta
    20341 ggttttttcc cacggtttcg ggcgcggcgg ctgcacggtt acggctttcg cttcctgctt
    20401 tttcggcgca acaggtttgt tatccgcgca cggcagatct tcgccatacg gatgcgggat
    20461 cgggtcgatt ttccctgggg tatcgagacg ggtggaatcc acgccgctcc agcctggcaa
    20521 cgcctctttt acgataatcg cagtattacg cacatcgcgg atttcactaa tcggctcgcc
    20581 catcgccaga cggtgcgcca cctccaccaa cggacgctca ccgttaccga acatcagcat
    20641 gtcggctttg gaatccacca gcacggaacg gcgcacggta tcggaccagt aatcataatg
    20701 cgcggtacgg cgcagactag cctcaatacc gccgaggatc accggcacat ctttccacgc
    20761 ctctttacaa cgctgggtat aaaccagtgt ggcgcgatcc gggcgcttac ccgcgacgtt
    20821 atccggcgtg taggcatcgt catgacgtaa acggcgatcg gcggtatagc ggttgatcat
    20881 cgaatccatg ttgccagcag taacaccaaa aaacagattc ggtttaccca gacgcataaa
    20941 gtcgtctttg ctgctccagt ccggctgggc gatgatccca acgcgaaagc cctgcgcttc
    21001 cagcatacga ccgcaaatcg ccatcccgaa gcttgggtga tcgacatacg cgtcgccagt
    21061 aaccaaaatg atgtcacagc tatcccagcc aagttgatcc atctcttcac gagacatcgg
    21121 caaaaacggt gccggtccaa aacaggcggc ccagtactgc ggccaggaga acaggtcgcg
    21181 atccggttgg atcagggaga tagagctcat tttgcttcca gaaatgataa aaaaataatc
    21241 aaaggccggg gattataagc cggaacgaaa gagaaatcga aaggtattcc atactcgccc
    21301 tcctcgggcg agtatgaaga ttacggtacc ggattgacca acagttgccc tatcgagcca
    21361 cggtccgcca tttccagcgt ctgactgttg aagtagaacg ggaagtgcgc ccaggaaggc
    21421 tgaccgaaat aaacaagcag ctccacttgt ccgtcaaccc aaacggtatc tttccagcct
    21481 ctgtcttccg ggaacggcat cgcgccattc acgttacgga tctggaacat cacaccttca
    21541 atatggaacg cttgcggctc gtccgcgcgt accgtccagc gttcccacgt tccttgctgc
    21601 gcggtgacat caatacggtt gacgtcccac agctgtccat taatacccgg gtcatcaccc
    21661 agactgatat cgcgactgcg aattggcgaa ccagccatga tttcagttgg cagcaagcgc
    21721 atcggaagac tgtctgtgac cagcggcaga aggccggttg ggcgcagcgt tagcaccagc
    21781 gtagaaacca gaatgctgga tggctcaaag aagccacgaa tacgatcaac aatgctcgcc
    21841 gcttcgccac aggtgatcga cacttcatca ccgttgctca tatccaccag aatctcacga
    21901 cgctcgcccg gtgccagcga aagttgcttc accgatacag gagcgggcag gaatccctga
    21961 tcgccagaaa tcacatgtaa cgggcgacca tcgctcatct gtagttgata gcgacgagag
    22021 ttcgacgcgt tcaacagacg caagcgcacc cagccacgcg agacttcaac gtacgggctt
    22081 tgtacaccgt taaccagcag cgtatcacca acaaagccgc cgcttcccgg ttcgttgtat
    22141 tctggcgtac caaagttatc cagccgttta tcctgaataa tgaccggaaa atcatccaca
    22201 ccataatggt tggggatagg cagcgacttg ctgacttcat cttccaccag ccacattccg
    22261 gcaaggccgt tatagacctg ctgagccgtg cggttgggag tattggcgtg ataccacaga
    22321 gtagctgcgt tctggcgaat aggcagtacg ggtgcccagt cagcgtttgg cgacatcatc
    22381 cgtgccggac cgcccatcag cgggccaggt acctgtagcc cggccaccgt cattgagaca
    22441 ttttctgtca ggcggttgct gtaaataagc ttaacatcgt cgcccttcca gacgcggata
    22501 gtcggcccca ggtaacgacc attgattccc caaaccgacg cgcgtgtccc tggcgtaaat
    22561 gaccagtgcg cacgttgtac agtcataaac agcggttgcc cacggcgaga ttcaagcagc
    22621 ggcggaacgg gtagcggttg ctgttgcccg gctgcgctgg ccttcagggg aacagcgcct
    22681 gcacaaagtg caatccccga tgcctgaatg aactgacgcc gactgagtga catatttgct
    22741 ccatgtaaaa ctggctaaag taataccgtg caggaaagtg ttccccgcaa aaatacagat
    22801 tgccgactta aacttttccg gcggcttcgc gctctgcgac ttctttatcg agctcggcga
    22861 ttttttgttc cattatcgaa cgacaatggg cagccagctc acgaacctga tctttgccat
    22921 actgactgac gtcaattggc ggcagcattt cgacaatcac cagaccgttg tgcagtcgat
    22981 taagattaat cttattcgaa gttgtagaga cgcacacggg aataatcggg acgcccgccg
    23041 caattgccgc gtgaaatgcc ccggttttga acggtagcag gccgcgacca cggctgcggg
    23101 ttccttccgg gaacatccag atggaaatac ggcgtttttt gaagtgattc acgacttccg
    23161 caatagtgcc gtgagcttta gtgcgattgt ttctgtcgat caataagttg ccggttaacc
    23221 agtacaactg cccgaagaag gggatccaca gcaagctctt tttacctacc gtcaccgtcg
    23281 gcggttgcac aatgttcgat gctgtgacca tgtcatagtt gttctggtgg ttagcgatat
    23341 agatagcatt gccgtagctt tcagcatccg caggtttgcg gcactcaact ttcaggccga
    23401 acagcggtgc aagacgacca aacatatgcc caaaggtggc cacatgtttc gggttacgcg
    23461 ggctgaaaag gcagtaaatg gagccgaata cacagactaa gatgctgtaa atcacggtaa
    23521 taataagacg aaagatatat agcataacac cctctgaagg tctgagagac tggcattgta
    23581 cgtcacctga aatcaggtta gggcattgtt aaaagccgct ctctggaaaa gcgtattgtt
    23641 aatcgcaacg catgaataaa caacggtttc aagggaattt ttatcgtttc cgggggttga
    23701 atacgctgcc ggatgacgac ttaacgtttc atccggcgtt ccttgcaagc gggaggaaac
    23761 agcgccctcc ccggcatatt actcttcgct atcaccgctg ctggcacggc gaggagagtc
    23821 gatctcaaca cgatcgatac gctgcaaacc gcgcatcaac gtaccgcggc gtccacgttc
    23881 gccagtgact ttctgtagct cttccggacg cagtttaatt ttgcgtttcc caacatgaat
    23941 ggtcagcgtg ctttgcggcg gcagaacgta cagttgcgcc agaccatcct cgccacgcgc
    24001 ggcttctgcc gacggaatgt tgataatctt attgcctttg cccttcgaca actgcggcag
    24061 atcgcttacc gggaacatca acatacggcc tgcctgagtg attgccagca gcatatcgga
    24121 agcatcctca atcaccaccg gcggcataac atgggcattt tccggtaagg tgatcaaagc
    24181 cttacctgca cggttacgcg ccaccagatc gttaaaggtg cagacgaaac cgtaacccgc
    24241 atcggaagcc atcagcagtt tctgatcgtc gctttccatc agcatatggt caacggtcgc
    24301 cccaggcggc aacgttaatt tgccggtgag cggttcgccc tgaccacgcg ccgacggcag
    24361 cgtaatcggg tcgatggcat agctacgacc ggtggaatca acaaacacta ccggttggtt
    24421 gctcttacct ttcaccgccg ctttgaagct atcgcccgct ttataattca ggcccggcgc
    24481 gtcgatatca tggcctttag cgctgcgtac ccagcccatc tgcgacagca caatggtgac
    24541 aggttcagac ggcagcatgt cgtgctcgct catcgctttc gcttcttcgc gttcctgcaa
    24601 cggcgaacga cgttcgtcac cgtaggcttg cgcgtctgcc tgcagttctt tcttcagcag
    24661 gttattcatt ttacgctcgg aagccaaaat gccctgcaac tggtcgcgct ctttttccag
    24721 ctcactctgc tcaccgcgaa tcttcatctc ttccagtttg gcaagatgac gcagtttcag
    24781 ttcgaggatc gcttccgctt gggtttccgt aaggccaaac cgcgacatca gcgccggttt
    24841 cggttcatct tcattacgaa tgatctcaat cacttcgtcg atattgagaa acgccaccag
    24901 caaaccttcg aggatatgca ggcgcttgag gactttctcc agacgataat tcagtcggcg
    24961 gcgcacggta tcgcggcgga acaccagcca ttcggagagg atttccagca ggtttttcac
    25021 cgccggacga ccatccagac cgatcatatt gaggttaatg cgatagctct tttccagatc
    25081 ggtggtagca aagaggtggt tcatcacctg atccatatcc acgcggttgg aacgcggcac
    25141 aatcaccaga cgggtcgggt tctcgtggtc agattcatcg cgcagatcgt caaccatcgg
    25201 cagctttttg ttgcgcattt gcgcagcaat ttgctccagt acgcgcgcac ctgaaacctg
    25261 atgcggcaat gcgctgataa ccaccgcgcc atcttctttc ttccaaaccg cgcgcatacg
    25321 cactgaacca cgtccgttct cgtagatttt acgaatctcg gcgcgcgaag tgataatttc
    25381 cgcttcagtc ggataatccg gcccctgcac gatatccagc agctgatcga gcgtggtttt
    25441 cggctggtcg attaatgcga ttgccgcctg agccacttca cgcaggttat gcggtggaat
    25501 atcggtcgcc atgccgacgg caataccggt ggtgccgtta agcaaaatgt ttggcagacg
    25561 ggcaggtagc attttcggct cctgcaaagt gccgtcgaag tttggcaccc agtcagccgt
    25621 cccctgcccc agctcgctca atagcagctc ggaatatttc gacaaccggg attcggtgta
    25681 acgcattgcc gcgaacgatt tcggatcgtc cggcgcaccc cagttcccct gaccatcaac
    25741 cagcggataa cggtaagaga acggctgcgc catcaggacc atcgcttcat aacaggcaat
    25801 atcgccgtgc ggatggtatt tacccagtac gtcaccgacg gtacgggccg attttttaaa
    25861 tttggcgctg gcattcaggc ccagttcaga catcgcatac acaatgcgcc gctgaacggg
    25921 tttcagacca tcaccaataa acggcaacgc acggtccatg atcacgtaca tggagtagtt
    25981 taagtaggcg ttttccgtaa attcatgtag cgcaaggcgc tctgccatat cgctcattaa
    26041 ttctgattcc tcaacttatt cgccagcctt caaaggggca atattgccgg agatactaca
    26101 ttatctgccg cgtcgagtca caggagatca gcgtgaatag cgccgccgga cgtgctccga
    26161 cggcgataaa ggcatcaatg tgccttgata tacaactctt tgctgtagac ataatcctgg
    26221 ggattatgca gcggaaaacc gccaacgtag ggtttaagca gtttgattaa cggctgatag
    26281 tagacaggaa tgagcggtgc ctgctggttg atgatcactt cggcctgctg atacaacgca
    26341 ttacgctttg ttgcatcagc cgtttgtgcc gcctggttta gtaaggtgtc atactgcgcg
    26401 tttttccagt ggccgacatt ttcctcgcta tcgctcttaa gcgtgttcag aaaggtggag
    26461 gcatcattgt acgtcgcatc ccacgactgc cgagacagca tgaaatcacc ggctcgtcgg
    26521 gcatcaagat aagttttcca ctccattgtg cgcagcgtca cctgtgcacc cagccatttt
    26581 ttccattcgg aagacaacgc tatcgcggtc ttttcatgca gatcgtactt gttgtagaac
    26641 agctcaaagc gtagcggatg agaggcgtcg tatcccgcct gtttcagcaa gacttttgcc
    26701 atcgcgacgc gctcactcat tggcttttgc agttcatcga acgtcgtcgc gctaaagcct
    26761 tttacctctg gcggcgtcag cgtggttgcg ggcgttctca accccagtac cttttgcgca
    26821 ataagctgtc gatcaaccgt aagatatagc gcccgacgca cccgcacatc gttaaatggc
    26881 ggtttctcaa ggttaaagtt gtaatattcg ctgttcagac gcggaataat tcgtagctcg
    26941 ccaggcagtg atttttcaat ggcgggaatt tgctgcgccg gaacccaggt gagatcgacc
    27001 tctcccgcgc gatagcggtt atagccggtg accgaattat ccagcgccag atactcaacc
    27061 tgttgcaata ctgtatgttg cgcatcgcgg tactttggat ttttgcgtgc agtaatcttt
    27121 tcgttaacta cccactgatc aagcacaaag gcaccgttgt aaaccatgtt ctctggctta
    27181 ctccagctat cgccatgttt agcgatgaca tgatgaggaa ccgggaacag cgtcggccag
    27241 gcgagcatcg tcgtgaacca aggaactggc tgctcaagcg taacttcaag agtacgatca
    27301 tccatcgctt tgacacccag cgatgtaaca tctgctttac ccgcaacaat agccgcggca
    27361 ttgttaatgt gcgcctgtgc cagatagcca gcaaaagggc ttgccgtttt cgggtcaacc
    27421 gcacgttgcc agccgaggac aaaatcctct gccgtcagag gctgaccgtc tgaccactgc
    27481 aaaccgctac gtagatggaa aatatagcgc ttgccgccgt ccagtatctc ccagcattca
    27541 gcctgagcgg gctgcacctg gccttcaccg tccatccata ccagaccttc aaacagatcc
    27601 agcacaatct gcgcggcagt attctcctcc accttttgcg ggtcgagcgt gcctgggtcg
    27661 ctatgattgt tgtaacgaaa aacttgttgc ggggcgagcg gtgtgttggc gggaacgtca
    27721 gcagcgtaga gaggagccgc acttaccagg ctgaccagcc ataataaatt tcgcgtatac
    27781 atggtattcc ttaccggaga aattataagc ccaacaacaa tacgcctgtg gcattgttcg
    27841 ctcaaactta tcgcgagtga tttggctcac actccggtaa agattcccca tcacgctaac
    27901 ggtacataaa catccgtttc cagtcgctgc tctgtcatcc cttcggcaag attggtgtag
    27961 tgaaacagga tcggggcttt gcgcattttt tcgccgcttg ccggaagcca gtggcgaatg
    28021 atgccccata tcgtgtgtga aatatcgtcc agctcgccaa catggcgggc cacagcataa
    28081 cgtccaccgg taagttcacc attacttacg ccataacgat tatcggggat cggttcgcta
    28141 acgctgccgc agatatcaaa gcgaaacgct tctggtgcgg tggtggcagg gtcgtcccag
    28201 gcgacgccaa aagtctggct ttggttaaca ggagaaagcc ccgtctcttt acgccacatg
    28261 ataaatttcg ccacgctgta gttgagcaac tcagggctac agcggtgcgg caacatcgcc
    28321 acagggattg atgggaaatc gataatattt acatccagtg tcaggtttgt cattttgcct
    28381 ccctgcgaaa ttattcccgg gaacgcgtcc cgggagcggt aacaattacg gatttacttt
    28441 gcggatctgt ttgacgtcaa tttcaacaga gttccagtct ttatcgactt caccctgaat
    28501 ctcaaccgta tctttcggcg tcaccgtcac gccgttccag cgtttgtgat cgatatccac
    28561 attgatagta ccgctggcat ctttgaacac gtagagatcg tcagagatgc gttcaacgat
    28621 attgccgcgc agggttaccc aggtgtcgtc acgcagggat tttgcgcttt ctacggtcgt
    28681 tacgctgccg ttcggcccct ggaatcctcc ggcctgactt tgtgttgccg atgggccaga
    28741 aaaacctccc tgctctgctg ccataaccgg tgcactgcac agggccatta ctgcgattac
    28801 tgctgcgaat tttttcatgt ttattactcc ctttaatgtc tgtttccgag catttaacaa
    28861 gatagtcctt aacaacttct taagggaaaa aaataaaatt taatgctgta cagagcgcgt
    28921 tacaacacgg tttactggca gcaaatacgg ttatcgcagg gatgaaaaaa tgcgaatttt
    28981 actgatagaa gatgacatgc tgattggcga cggcatcaaa acgggcctta gtaaaatggg
    29041 ttttagcgtc gactggttta cacaaggtcg tcagggaaaa gaggcgctat atagcgcacc
    29101 ttatgatgcg gtgatcctgg atttaacctt accgggcatg gatggtcgcg atattttgcg
    29161 cgaatggcga gaaaaaggtc agcgtgagcc ggtattgatc ctgaccgcgc gcgatgcgct
    29221 ggcggaacgt gtagaagggc tgcgtctggg agctgacgat tatctgtgta aaccttttgc
    29281 gttgatagaa gtcgccgcca ggctggaagc tctgatgcgc cgaaccaacg gccaggccag
    29341 caacgagctg cgccacggca acgtcatgct cgaccccggc aaacgtatcg ccacgctggc
    29401 tggcgaaccc ttaacgctga aaccaaaaga atttgccctg ctggaattac tgatgcgtaa
    29461 cgctggtcgg gtactgccgc gcaaactgat tgaagagaaa ctgtatacct gggacgaaga
    29521 ggtcaccagt aatgccgttg aagtgcatgt gcatcatctg cgacgcaaac tcggcagtga
    29581 ttttattcgt accgttcatg gtattggcta cacattaggt gagaaatgaa atttacccaa
    29641 cgtcttagtc tgcgagtcag gctgacgcta atctttttaa ttctggcctc ggtgacctgg
    29701 ctgttttcca gctttgtcgc ctggaaacaa acaacggata acgtcgatga gttgttcgac
    29761 acccaactga tgctgtttgc caaacggtta agtacgctcg atctcaacga aatcaacgcg
    29821 gcggatcgca tggcacagac gccaaataaa ttaaaacacg gtcatgttga tgacgatgcg
    29881 ctgacctttg ccatctttac ccacgacggc agaatggtcc ttaacgatgg cgataacgga
    29941 gaagatattc cttatagcta tcagcgggaa ggttttgctg acgggcaact ggtcggtgaa
    30001 gacgatccct ggcgttttgt ctggatgacc tcacctgatg gcaaatatcg catcgttgtt
    30061 ggtcaggaat gggaataccg tgaagacatg gcgctggcga ttgttgccgg acaattgatc
    30121 ccgtggctgg tcgcactgcc gattatgtta atcatcatga tggtactact gggtcgtgaa
    30181 ctcgcgccgc tgaacaaact ggcgctggca ctacgtatgc gtgacccaga ctcggaaaaa
    30241 ccactaaacg cgacgggcgt acccagcgaa gtgcgtccac tggttgagtc gttgaatcaa
    30301 ctgttcgccc gcacacatgc gatgatggtt cgtgaacgac gctttacctc cgacgcagct
    30361 cacgaacttc gtagcccgtt aacggcgctg aaagtgcaaa ccgaagttgc tcagctctct
    30421 gacgatgatc cgcaggcgcg gaaaaaagcg ctgctccaat tacattccgg gatcgatcgt
    30481 gctactcgtc tggttgatca actgctcacg ctatcgcggc tggactcact ggataacctt
    30541 caggacgtcg cggagatccc gcttgaagat ctcctgcaat cgtcggtgat ggatatttac
    30601 cacacggcgc agcaggcgaa aattgacgtg cgactgacac tcaatgccca cggcatcaaa
    30661 cgcaccggac aaccgctgtt gctaagtttg ttggtacgaa accttctgga taacgccgtg
    30721 cgctacagtc cacagggctg cgtggtggac gtcacgctga atgccgataa tttcatcgtg
    30781 aaggataacg gccccggtgt gacaccagag gcactggcga gaattggcga acgcttctat
    30841 cgcccacccg gacaaaccgc taccggcagt ggacttgggc tatcgattgt ccagcgaatc
    30901 gccaaattgc atggcatgaa tgttgagttt gggaatgcgg aacaaggtgg atttgaggcg
    30961 aaggtaagct ggtaacttct ctgtctatga gagccgttaa aacgactctc atagacttta
    31021 ctaatagcaa aatataaacc gtccccaaaa aagccaccaa ccacaaccca aacaaataac
    31081 gagcgagaat acatatagcc aaaactcgaa catttcccgc ataaagagtt ttcttaagat
    31141 aagaataata agtggcgtca gaagaaaaaa tgctgcaatc attgcttgca atatacgatc
    31201 ttcgcctgaa acggaaggta tactgcaaat attgtctccc gactcaagca tccagtcata
    31261 cttattgaaa gcaaaaaaag catctattaa ccaataagta agcattatgt ataacagagc
    31321 ttcaaatatt gtttgaattt tatgctttaa catatgttag cactctctaa aaaagtccag
    31381 tcggagatct ggttttcgat accctccagt aaatctattt aaaataatct gcgtaacacg
    31441 ctgatatttt catttttagt tattcaacac cacaattatc aactcgcaga aagtccacac
    31501 caacgttgta aattaaccct gtgctagttg gaatgatgag aaattgctat cagtattgtc
    31561 attttcagaa aatatttatc ccgcatcggt gaatcagagc aagatcagac ttttgctaaa
    31621 ttcgcaaaag actttgcaca ttttgctaat ttcaccgtac cgctctgtga cgtactatag
    31681 tcggcaaacg tctcaccttg aggttaaaaa atgagcaaca tcctgattat caacggcgcg
    31741 aaaaaattcg cccactccaa tggtcaactg aacgacaccc tgaccgaagt cgcggatggc
    31801 acactgcgcg acctcgggca tgatgtccgc atcgttcgcg ccgacagcga ctacgatgtc
    31861 aaagcggaag tacaaaactt tctctgggct gatgtggtga tctggcagat gccaggctgg
    31921 tggatgggcg cgccgtggac agtgaaaaaa tacattgatg atgtatttac cgaaggtcac
    31981 gggacgctgt atgccagcga tggtcgtacc cgcaaagatc cgtcgaaaaa atacggttct
    32041 ggcggtctgg tacaaggtaa aaaatatatg ctttccctga cctggaacgc accaatggaa
    32101 gctttcaccg aaaaagatca gttcttccac ggggttggcg ttgacggtgt gtatctacca
    32161 ttccataaag caaaccaatt ccttggtatg gaaccgctgc cgacatttat cgctaatgac
    32221 gtgataaaaa tgcctgatgt tccccgctat actgaagaat atcgcaagca tcttgtggaa
    32281 atttttggtt aactagagct ctggctttag aaggagttaa ccatgattac agtaatcgca
    32341 gaaatccgta ctcgtcctgg tcaacatcac cgtcaggcag tgttggatca gtttgctaaa
    32401 atcgttccaa ccgtactgaa agaagaaggt tgccacggct atgcgccaat ggtggattgc
    32461 gctgctggcg tgagtttcca gtctatggca ccggattcta tcgtgatgat tgagcagtgg
    32521 gaaagcatcg cgcatcttga agcgcatctg caaaccccgc acatgaaagc atatagcgaa
    32581 gccgtaaaag gtgacgtgct ggagatgaat attcgtatcc tgcagccggg gctttgacat
    32641 ttctaaaaag aggccggtgc tgctaccggt ctcagcccag attagccatt ctttcttccc
    32701 gttttcagtc ctcgatggaa atcgttaatt cgcttaatgg ttttaaccgc acgctgcggc
    32761 actgcggaag ctaccgacca gacaatcatt tccagacaca acaataccgt accatgtagc
    32821 ggcgttttcc ctttttcatc cccgcgcgga acatgaatca cgatactggc gtctttgcta
    32881 aaacgtgaat ccagcgcgtt tgtcagcaaa ataacaggga tccccagccg cctcgcctca
    32941 cgaagcgttg tcagcccttc ccggtgcgca gatttttgcg ccatcatgat cagaacatcg
    33001 ccacgttgaa gcgcgatcag ttgctcggca aggccaatac ccgtacggtt tagtgccgtg
    33061 gcaggcaaac ctatgcggtt gaatagtcgt gcggtatagt ccgccaggat acccgaagcg
    33121 ccaatgccaa aaatagcgac ttgccgtgcc tgcaccaaca acgctacagc ttgcgcaagc
    33181 gcgtggcggt tttcaggctc tgacaggaca ttacaggtat acaaatgccc ttcaagaaca
    33241 aagtcgattg cggtgttaac atcgctcgtc aagttactca ccgtcgtaga catcttttcg
    33301 ctggaactaa gggctggacc aagccactgt tccagagtgc gtttcagatc acgcagcccg
    33361 gcaaacccca gggcctgtat agccctgata actgtggcat cggaagtgtt caacgtggcc
    33421 gcaatttcca tcgccgtttg ctcgagtacc acttcacgat gctcattaat gtagctggcg
    33481 acaactctta acccaggcgt taactgactc gcgcgagtgc gaaaacgctc accaaaaata
    33541 tcaacccgca ctttatcttt ctggatcatt tatcctccgg tagaggtcgt cctgcaattt
    33601 gtgattgtat ctgcgcagcc atcagcccca gagatgcaaa ggagttagaa attgcctctt
    33661 cacgagagat cagcacataa cgcccggaac gacaggcagt cagaaactga caccatcccg
    33721 gcatgacttt ttccattgct gccagctcat cctgaggttt accaccggtg tcaccgcgcc
    33781 aggttgcaaa aacaaaatcg gcatccaatt caggtaaacg ctccgcgctc acatccattc
    33841 gcccaccttc aggaatgctc tcaatcagcg gcggaaaacg aaaaccagca tcgcgtaata
    33901 cccgccccag cgaatgatag ctatgcatca cattaatttt tccctggttt gcctgaatca
    33961 ccgataccgt tattttttgg ctgtccagcg tcgccttcag cgcattgatt tgtgcctgat
    34021 agcggcgttc aagtatcgcc agctgcgact gcgttcctgt aagttctgcc agcttgcgat
    34081 agatttctgg cgcgccccct ttgagatgat caatgctcac cgtgggcgca attttttcaa
    34141 gttgttcaat gggcgtatta cgggtcggtt ctgtgatgat caggtcaggc tttgccgcca
    34201 caatcgcttc aatatcaata tcagcggtac caataaaggc gatcgatgaa ttatcaaagt
    34261 cgacacctgt caataacgcg ccagatcgaa tgaaatggct accgtcaggc cgagttcgcc
    34321 cgtggctggc gacaggaggt acaccgagct caatcagagg aatagtgata tcaagatcgt
    34381 gtaaagagac aattctcttt ggatgagcag gaacagtgac tttgcgccct aaatcatcag
    34441 taaatacctg aacaggttct gttgcacggg aaaaaaatga caacagtatc agcagagaaa
    34501 aaaataaacg catataactc ccgttaaaaa ctgttcctgc gctgccagag cagtagcaaa
    34561 aaaaatggtc caccaatcag tgagataatg attccggcag gcagttgcaa aggcaaaaaa
    34621 gccaaacgac caatgctatc cgccagaata actaacaacg cccccgatac ggcgctcccc
    34681 agcagtaatg tcgtctgccc gccacgtaga ataaaacgtg atatatgggg tgctatcaat
    34741 ccgacaaaac cgatgttacc aacacacgaa acgcagacgg ctgtcaggat tatgggtgcg
    34801 gcgacacgta acaacgccag gcgagaacta ttcaccccta acccggttgc cacctgatga
    34861 ccaagcagag cgatatccgc cgtcctggcg gtgaacagca ataaaagagc ggctggcaac
    34921 atccaacagg ctgaaatacc gactaacatc cagttagctg catgcaggct tcccgataac
    34981 cacatcaatg cagtttgtac atctcgaaca tctgcagtgg tcataaatac accgataccg
    35041 gcggcgaaaa accaggaaac accaatacca atcagaacaa atcgcgggcg ggaaatatcg
    35101 cgcgcacaaa aaatcacgat taaagccacc aacaggccac cagcaagacc agccactgga
    35161 cgccagaaca ctcccagcat tggaaactgg aaaatcagcc acagcaccgc cacgctacat
    35221 ccttctttga cgccgattaa accaggatcg gcaaggccgt tacgcgcaat ggattgcatc
    35281 gcggcccccg ccatacctaa catggctccg catagcaatg ccatgatgac tctcggcaag
    35341 cgaatatcct gcacaatata acgtgcgtct gtgcttacgt tttctggaga gaacaatgct
    35401 cgtcctactt ccgatgccgg gacggagaaa gagccatgca tcagaccgaa tatcagtatt
    35461 ccaaccgcaa acagaaacaa cccaccaagc aacagcagat ttttagggcg taccagtgtc
    35521 gaaaacttac caacacgtag tgggcgtagc ccgacgttca ttatccgact catttgaaca
    35581 tcctcgtcgc cataatgaca aaaacaggcg caccaactaa cgccgtcatg acaccggtcg
    35641 ctaactcatg gggcgtgaaa agcgtacggg caataatatc tgccagtaat aacaaaagtg
    35701 cgccgacaca agctgaaaga gggagcagaa cgcgcagatc cgctgatacc agacgccgga
    35761 caatctgcgg tactaacagg ccgacaaaac caatggggcc agcaatcgat acggctgcgc
    35821 cacagagcaa cgcgatcgca agcagggtga atgttcgcgt gcggaataca gagacgccca
    35881 gcccctgcgc catgcgatcg cccagtgcca acatgttaag ggagggtgca aggtaaaggg
    35941 ctaacacaaa tccccccaga gaaaaccagg cggacgtacc cagcgtcgcc caatcctgcc
    36001 ccgctaaatc acctgctagc catgtccgca tcgccagcag tttttgttcg tcaagaatca
    36061 ggattgcagc cgttattgag gacacgaacg ccgatagcgc cacgccgcat aaagtaactt
    36121 tcattggcgt taaccctgaa cgccctgcgg aggaaagcag caatatcaac aggaacaata
    36181 acgcgccgcc cgtagatgcc agcagtgggc gtccaaccgg aaaggccagc ccaagcgcac
    36241 tggcagcaac gacagcaaga gcggctccgg catttaagcc taaaatatgt ggctccccca
    36301 atgggttacg aatgacagcc tgcaacaaag caccagcaac tccaagagaa gcaccggtaa
    36361 gcaatgctgc cgctaaacgc ggcaaacgga gtcttacaat tacgttgtga tcgaagtttt
    36421 gcggatcaaa atgaagaaat gcctgcaaca ccgtttgtgg tgcaataaat cgggcaccaa
    36481 tccctggata taccacgcat cccaccagca gtaaggcgag gaaaattaca gtaaccagcc
    36541 ctgtgcgcat catacttttt ctacaccacg aaacggcatg aagaacggct ttcccgtcag
    36601 aggatttatt gatgcgtgaa catcaacgtc aaagaccgct tttaccagct caggcgtgca
    36661 atgctccccc tcattcaaca cacgcaccac tttcccctgg cgtaaaaata tcaacgtatc
    36721 gccataattg acggcaaaat tcagatcatg caacaccacg acgactgtac gcccgtgatg
    36781 acgtgttaaa tcatgtaata actcaagaat ttcaacctga taacgtaaat caagccaggt
    36841 tgtgggttca tccagcagga tataaggcgt cttttgcgcc aacaccatcg caatccagca
    36901 acgctggcgc tgcccaccag agagtttttc aacaggtaaa tgtgcaaact cctgcgtacc
    36961 cgttaatttc agggcctctt ctaccgccag ctcatcggcg tcgctccatt gacgaatgaa
    37021 attctgccag ggaaaacgcc cacgcgacac cagttcataa acggttaagc cctccggcaa
    37081 taatggcgac tgcggcaaga tcccaagtct acgggataac gctttcgttg gttgctcgtg
    37141 aatcgcttta ccatccagca atattgagcc gcccatgggt tgcaagatac gtgcaatggt
    37201 gctgagcaac gtcgactttc cacagccgtt tgccccaacc agaacggtca ttttttctgt
    37261 gggaacggag aaagaaacac catcaacaat gattttcttg tgatacccgg cagaaacatt
    37321 gtcgaggatc agcccctgcc cttttgcgtt atgtgccacg tgtacgccaa cttaatcaaa
    37381 gacaaacaaa aataaaactc attctccttt gagagtttga cgccacaaaa tgtagtagtc
    37441 aagcagttaa aagccacaca aaaacaaggt aaat
//
LOCUS       DADXDL010000043        37379 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.043, whole genome shotgun sequence.
ACCESSION   DADXDL010000043 DADXDL010000000
VERSION     DADXDL010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37379)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37379)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37379
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.043"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            140..835
                     /gene="araD"
                     /locus_tag="IRB70_002473"
     CDS             140..835
                     /gene="araD"
                     /locus_tag="IRB70_002473"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBC0632378.1"
                     /translation="MLEDLKRQVLEANLALPKHNLVTLTWGNVSAVDRERGVFVIKPS
                     GVDYSVMTADDMVVVSIETGEVVEGTKKPSSDTPTHRLLYQAFPSIGGIVHTHSRHAT
                     IWAQAGQSIPATGTTHADYFYGTIPCTRKMTDAEINGEYEWETGNVIVETFEKQGIDA
                     AQMPGVLVHSHGPFAWGKNAEDAVHNAIVLEEVAYMGIFCRQLAPQLPDMQQTLLDKH
                     YLRKHGAKAYYGQ"
     gene            910..3261
                     /gene="polB"
                     /locus_tag="IRB70_002474"
     CDS             910..3261
                     /gene="polB"
                     /locus_tag="IRB70_002474"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase II"
                     /protein_id="HBC0632379.1"
                     /translation="MAQAGFILTRHWRDTPQGTEVSFWLATDNGPLQVTLAPQESVAF
                     IPADQVPRAQHILQGEQGFRLTPLALKDFHRQPVYGLYCRAHRQLMNYEKRLREGGVT
                     VYEADVRPPERYLMERFITSPVWVEGDMHNGTIVNARLKPHPDYRPPLKWVSIDIETT
                     RHGELYCIGLEGCGQRIVYMLGPENGDASSLDFELEYVASRPQLLEKLNTWFANYDPD
                     VIIGWNVVQFDLRMLQKHAERYRLPLRLGRDNSELEWREHGFKNGVFFAQAKGRLIID
                     GIEALKSAFWNFSSFSLETVAQELLGEGKSIDNPWDRMDEIDRRFAEDKPALATYNLK
                     DCELVTQIFHKTEIMPFLLERATVNGLPVDRHGGSVAAFGHLYFPRMHRAGYVAPNLG
                     EVPPHASPGGYVMDSRPGLYDSVLVLDYKSLYPSIIRTFLIDPVGLVEGMAQPDPEHS
                     TEGFLDAWFSREKHCLPEIVTNIWHGRDEAKRQGNKPLSQALKIIMNAFYGVLGTTAC
                     RFFDPRLASSITMRGHQIMRQTKALIEAQGYDVIYGDTDSTFVWLKGAHSEEEAAKIG
                     RALVQHVNAWWAETLQKQRLTSALELEYETHFCRFLMPTIRGADTGSKKRYAGLIQEG
                     DKQRMVFKGLETVRTDWTPLAQQFQQELYLRIFRNEPYQEYVRETIDKLMAGELDARL
                     VYRKRLRRPLSEYQRNVPPHVRAARLADEENQKRGRPLQYQNRGTIKYVWTTNGPEPL
                     DYQRSPLDYEHYLTRQLQPVAEGILPFIEDNFATLMTGQLGLF"
     gene            3426..6332
                     /gene="rapA"
                     /locus_tag="IRB70_002475"
     CDS             3426..6332
                     /gene="rapA"
                     /locus_tag="IRB70_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001117023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-associated protein RapA"
                     /protein_id="HBC0632380.1"
                     /translation="MPFTLGQRWISDTESELGLGTVVAVDARTVTLLFPSTGENRLYA
                     RSDSPVTRVMFNPGDTITSHDGWQMQVEEVKEENGLLTYIGTRLDTEESGVALREVFL
                     DSKLVFSKPQDRLFAGQIDRMDRFALRYRARKYSSEQFRMPYSGLRGQRTSLIPHQLN
                     IAHDVGRRHAPRVLLADEVGLGKTIEAGMILHQQLLSGAAERVLIIVPETLQHQWLVE
                     MLRRFNLRFALFDDERYAEAQHDAYNPFDTEQLVICSLDFARRSKQRLEHLCEAEWDL
                     LVVDEAHHLVWSEDAPSREYQAIEQLAEHVPGVLLLTATPEQLGMESHFARLRLLDPN
                     RFHDFAQFVEEQKNYRPVADAVAMLLAGNKLSNDELNMLGEMIGEQDIEPLLQAANSD
                     SEDAQSARQELVSMLMDRHGTSRVLFRNTRNGVKGFPKRELHTIKLPLPTQYQTAIKV
                     SGIMGARKSAEDRARDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLV
                     ICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIG
                     SEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQAHDIQIHVPYLEKTAQSVLVRW
                     YHEGLDAFEHTCPTGRTIYDSVYNDLINYLASPDQTEGFDDLIKNCREQHEALKAQLE
                     QGRDRLLEIHSNGGEKAQALAESIEEQDDDTNLIAFAMNLFDIIGINQDDRGDNMIVL
                     TPSDHMLVPDFPGLSEDGITITFDREVALAREDAQFITWEHPLIRNGLDLILSGDTGS
                     STISLLKNKALPVGTLLVELIYVVEAQAPKQLQLNRFLPPTPVRMLLDKNGNNLAAQV
                     EFETFNRQLNAVNRHTGSKLVNAVQQDVHAILQLGEAQIEKSARALIDAARNEADEKL
                     SAELSRLEALRAVNPNIRDDELTAIESNRQQVMESLDQAGWRLDALRLIVVTHQ"
     gene            6344..7003
                     /gene="rluA"
                     /locus_tag="IRB70_002476"
     CDS             6344..7003
                     /gene="rluA"
                     /locus_tag="IRB70_002476"
                     /EC_number="5.4.99.28"
                     /EC_number="5.4.99.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional tRNA pseudouridine(32) synthase/23S
                     rRNA pseudouridine(746) synthase RluA"
                     /protein_id="HBC0632381.1"
                     /translation="MGMENYNPPQEPWLVILYQDDHIMVVNKPSGLLSVPGRLEEHKD
                     SVMTRIQRDYPQAESVHRLDMATSGVIVVALTKAAERELKRQFREREPKKQYVARVWG
                     HPSPAEGLVDLPLICDWPNRPKQKVCYETGKPAQTEYEVVEYAADNTARVVLKPITGR
                     SHQLRVHMLALGHPILGDRFYASPEARAMAPRLLLHAEMLTITHPAYGNSMTFKAPAD
                     F"
     gene            7216..7394
                     /locus_tag="IRB70_002477"
                     /pseudo
     CDS             7216..7394
                     /locus_tag="IRB70_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244358.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(7411..7569)
                     /locus_tag="IRB70_002478"
     CDS             complement(7411..7569)
                     /locus_tag="IRB70_002478"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632382.1"
                     /translation="MNGATSLYDEVIIINKIPPKKIDTKGVATEEVATKKVLLNKLLT
                     TQLLNEPE"
     gene            complement(7566..8232)
                     /locus_tag="IRB70_002479"
                     /pseudo
     CDS             complement(7566..8232)
                     /locus_tag="IRB70_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518734.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(8527..9342)
                     /gene="djlA"
                     /locus_tag="IRB70_002480"
     CDS             complement(8527..9342)
                     /gene="djlA"
                     /locus_tag="IRB70_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone DjlA"
                     /protein_id="HBC0632383.1"
                     /translation="MQYWGKIIGVAVALLMGGGFWGVVLGLLIGHMFDKARSRKMAWF
                     ANQRERQALFFATTFEVMGHLTKSKGRVTEADIHIASQLMDRMNLHGASRTAAQNAFR
                     VGKSDNYPLREKMRQFRSVCFGRFDLIRMFLEIQIQAAFADGSLHPNERAVLYVIAEE
                     LGISRAQFDQFLRMMQGGAQFGGGYQQQTGGGNWQQAQRGPTLEDACNVLGVKPTDDA
                     TTIKRAYRKLMSEHHPDKLVAKGLPPEMMEMAKQKAQEIQQAYELIKQQKGFK"
     gene            9597..11951
                     /gene="lptD"
                     /locus_tag="IRB70_002481"
     CDS             9597..11951
                     /gene="lptD"
                     /locus_tag="IRB70_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS assembly protein LptD"
                     /protein_id="HBC0632384.1"
                     /translation="MKKRIPTLLATMIATALYSQQGLAADLASQCMLGVPSYDRPLVQ
                     GDTNDLPVTINADHAKGDYPDDAVFTGSVDIMQGNSRLQADEVQLHQKEAPGQPEPVR
                     TVDALGNVHYDDNQVILKGPKGWANLNTKDTNVWEGDYQMVGRQGRGKADLMKQRGEN
                     RYTILDNGSFTSCLPGSDTWSVVGSEIIHDREEQVAEIWNARFKVGPVPIFYSPYLQL
                     PVGDKRRSGFLIPNAKYTTTNYFEFYLPYYWNIAPNMDATITPHYMHRRGNIMWENEF
                     RYLSQAGAGLMELDYLPSDKVYEDEHPNDDSSRRWLFYWNHSGVMDQVWRFNVDYTKV
                     SDPSYFNDFDNKYGSSTDGYATQKFSVGYAVQNFNATVSTKQFQVFSEQNTSSYSAEP
                     QLDVNYYQNDVGPFDTRIYGQAVHFVNTRDDMPEATRVHLEPTINLPLSNNWGSINTE
                     AKLLATHYQQTNLDWYNSRNTTKLDESVNRVMPQFKVDGKMVFERDMEMLAPGYTQTL
                     EPRAQYLYVPYRDQSDIYNYDSSLLQSDYSGLFRDRTYGGLDRIASANQVTTGVTSRI
                     YDDAAVERFNISVGQIYYFTESRTGDDNITWENDDKTGSLVWAGDTYWRISERWGLRG
                     GIQYDTRLDNVATSNSSIEYRRDEDRLVQLNYRYASPEYIQATLPKYYSTAEQYKNGI
                     SQIGAVASWPIADRWSIVGAYYYDTNANKQADSMLGVQYSSCCYAIRVGYERKLNGWD
                     NDKQHAVYDNAIGFNIELRGLSSNYGLGTQEMLRSNILPYQNTL"
     gene            12004..13290
                     /gene="surA"
                     /locus_tag="IRB70_002482"
     CDS             12004..13290
                     /gene="surA"
                     /locus_tag="IRB70_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase SurA"
                     /protein_id="HBC0632385.1"
                     /translation="MKNWKTLLLGIAMIANTSFAAPQVVDKVAAVVNNGVVLESDVDG
                     LMQSVKLNAAQARQQLPDDATLRHQIMERLIMDQIILQMGQKMGVKISDEQLDQAIAN
                     IAKQNNMTLDQMRSRLAYDGLNYNTYRNQIRKEMIISEVRNNEVRRRITILPQEVESL
                     AQQVGNQNDASTELNLSHILIPLPENPTSDQVNEAESQARAIVDQARNGADFGKLAIA
                     HSADQQALNGGQMGWGRIQELPGIFAQALSTAKKGDIVGPIRSGVGFHILKVNDLRGE
                     SKNISVTEVHARHILLKPSPIMTDEQARVKLEQIAADIKSGKTTFAAAAKEFSQDPGS
                     ANQGGDLGWATPDIFDPAFRDALTRLNKGQMSAPVHSSFGWHLIELLDTRNVDKTDAA
                     QKDRAYRMLMNRKFSEEAASWMQEQRASAYVKILSN"
     gene            13290..14279
                     /gene="pdxA"
                     /locus_tag="IRB70_002483"
     CDS             13290..14279
                     /gene="pdxA"
                     /locus_tag="IRB70_002483"
                     /EC_number="1.1.1.262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HBC0632386.1"
                     /translation="MVKTQRVVITPGEPAGIGPDLVVQLAQREWPVELVVCADATLLT
                     NRAAMLGLPLTLRPYSPNSPAQPQTAGTLTLLPVALRAPVTAGQLAVENGHYVVETLA
                     RACDGCLNGEFAALITGPVHKGVINDAGIPFTGHTEFFEERSQAKKVVMMLATEELRV
                     ALATTHLPLRDIADAITPALLHEVIAILHHDLRTKFGIAEPRILVCGLNPHAGEGGHM
                     GTEEIDTIIPVLNELRAQGMKLNGPLPADTLFQPKYLDNADAVLAMYHDQGLPVLKYQ
                     GFGRGVNITLGLPFIRTSVDHGTALELAGRGEADVGSFITALNLAIKMIVNTQ"
     gene            14276..15097
                     /gene="rsmA"
                     /locus_tag="IRB70_002484"
     CDS             14276..15097
                     /gene="rsmA"
                     /locus_tag="IRB70_002484"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBC0632387.1"
                     /translation="MNNRVHQGHLARKRFGQNFLNDQFVIDSIVSAINPQKGQAMVEI
                     GPGLAALTEPVGERLDQLTVIELDRDLAARLQTHPFLGPKLTIYQQDAMTFNFGELAE
                     KMGQPLRVFGNLPYNISTPLMFHLFSYTDAIADMHFMLQKEVVNRLVAGPNSKAYGRL
                     SVMAQYYCNVIPVLEVPPSAFTPPPKVDSAVVRLVPHATMPHPVKDVRVLSRITTEAF
                     NQRRKTIRNSLGNLFSVEVLTGMGIDPAMRAENISVAQYCQMANYLAENAPLQES"
     gene            15100..15477
                     /gene="apaG"
                     /locus_tag="IRB70_002485"
     CDS             15100..15477
                     /gene="apaG"
                     /locus_tag="IRB70_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Co2+/Mg2+ efflux protein ApaG"
                     /protein_id="HBC0632388.1"
                     /translation="MINSPRVCIQVQSVYIEAQSSPDNERYVFAYTVTIRNLGRAPVQ
                     LLGRYWLITNGNGRETEVQGEGVVGVQPLIAPGEEYQYTSGAIIETPLGTMQGHYEMI
                     DENGVPFSIDIPVFRLAVPTLIH"
     gene            15484..16326
                     /gene="apaH"
                     /locus_tag="IRB70_002486"
     CDS             15484..16326
                     /gene="apaH"
                     /locus_tag="IRB70_002486"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     ApaH"
                     /protein_id="HBC0632389.1"
                     /translation="MATYLIGDVHGCYDELIALLHKVEFTPGKDTLWLTGDLVARGPG
                     SLDVLRYVKSLGDSVRLVLGNHDLHLLAVFAGISRNKPKDRLTPLLEAPDADELLNWL
                     RRQPLLQIDEEKKLVMAHAGITPQWDLQTAKECARDVEAVLSSDSYPFFLDAMYGDMP
                     NNWSPELRGLGRLRFITNAFTRMRFCFPNGQLDMYSKESPEEAPAPLKPWFAIPGPVA
                     EEYSIAFGHWASLEGKGTPEGIYALDTGCCWGGSLTCLRWEDKQYFVQPSNRHKDLGE
                     AAAS"
     gene            complement(16404..16883)
                     /gene="folA"
                     /locus_tag="IRB70_002487"
     CDS             complement(16404..16883)
                     /gene="folA"
                     /locus_tag="IRB70_002487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020456510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 3 dihydrofolate reductase"
                     /protein_id="HBC0632390.1"
                     /translation="MISLIAALAVDRVIGMENAMPWNLPADLAWFKRNTLNKPVIMGR
                     HTWESIGRPLPGRKNIILSSQPGTDDRVTWVKSVDEAIAACGDVPEIMVIGGGRVYEQ
                     FLPKAQKLYLTHIDAEVEGDTHFPDYEPDDWESVFSEFHDADAQNSHSYCFEILERR"
     gene            complement(17076..18938)
                     /gene="kefC"
                     /locus_tag="IRB70_002488"
     CDS             complement(17076..18938)
                     /gene="kefC"
                     /locus_tag="IRB70_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefC"
                     /protein_id="HBC0632391.1"
                     /translation="MDSHTLIQALIYLGSAALIVPIAVRLGLGSVLGYLIAGCIIGPW
                     GLRLVTDAESILHFAEIGVVLMLFIIGLELDPQRLWKLRAAVFGGGALQMVICGGLLG
                     LFCMLLGLRWQVAELIGMTLALSSTAIAMQAMNERNLMMTQMGRSAFAVLLFQDIAAI
                     PLVAMIPLLAASSASTTMGAFALSALKVAGALVLVVLLGRYVTRPALRFVARSGLREV
                     FSAVALFLVFGFGLLLEEVGLSMAMGAFLAGVLLASSEYRHALESDIEPFKGLLLGLF
                     FIGVGMSIDFGTLLENPLRIVILLLGFLIIKIAMLWLIARPLQVPNKQRRWFAVLLGQ
                     GSEFAFVVFGAAQMANVLEPEWAKSLTLAVALSMAATPILLVILNRLEQSSTEEAREA
                     DEIDEEQPRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDA
                     TRMDLLESAGAAKAEVLINAIDDPQTNLQLTEMVKEHFPHLQIIARARDVDHYIRLRQ
                     AGVEKPERETFEGALKTGRLALESLGLGPYEARERADVFRRFNIQMVEEMAMVENDTK
                     ARAAVYKRTSAMLSEIITEDREHLSLIQRHGWQGTEEGKHTGNMADEPETKPSS"
     gene            complement(18931..19461)
                     /gene="kefF"
                     /locus_tag="IRB70_002489"
     CDS             complement(18931..19461)
                     /gene="kefF"
                     /locus_tag="IRB70_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     oxidoreductase KefF"
                     /protein_id="HBC0632392.1"
                     /translation="MILIIYAHPYPHHSHANKRMLEQARTLEGVEIRSLYQLYPDFNI
                     DIAAEQEALSRADLIVWQHPMQWYSIPPLLKLWIDKVFSHGWAYGHGGTALHGKHLLW
                     AVTTGGGESHFEIGAHPGFDVLSQPLQATAIYCGLNWLPPFAMHCTFICDDETLEGQA
                     RHYKQRLLEWQEAHHG"
     gene            complement(19569..20900)
                     /locus_tag="IRB70_002490"
     CDS             complement(19569..20900)
                     /locus_tag="IRB70_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0632393.1"
                     /translation="MQPSRNFDDLKFSSIHRRILLWGSGGPFLDGYVLVMIGVALEQL
                     TPALKLDADWIGLLGAGTLAGLFVGTSLFGYISDKVGRRKMFLIDIIAIGVISVATMF
                     VSSPVELLVMRVLIGIVIGADYPIATSMITEFSSTRQRAFSISFIAAMWYVGATCADL
                     VGYWLYDVEGGWRWMLGSAAIPCLLILIGRFELPESPRWLLRKGRVKECEEMMIKLFG
                     EPVAFDEEQPQQTRFRDLFNRRHFPFVLFVAAIWTCQVIPMFAIYTFGPQIVGLLGLG
                     VGKNAALGNVVISLFFMLGCIPPMLWLNTAGRRPLLIGSFAMMTLALAVLGLIPDMGI
                     WLVVMAFAVYAFFSGGPGNLQWLYPNELFPTDIRASAVGVIMSLSRIGTIVSTWALPI
                     FINNYGISNTMLMGAGISLFGLLISVAFAPETRGMSLAQTSNMTIRRQRAG"
     gene            complement(20958..21245)
                     /gene="fixX"
                     /locus_tag="IRB70_002491"
     CDS             complement(20958..21245)
                     /gene="fixX"
                     /locus_tag="IRB70_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like protein FixX"
                     /protein_id="HBC0632394.1"
                     /translation="MTSPVNVDVKLGVNKFNVDEEHPHIVVKADADKQVLELLVKACP
                     AGLYKKQDDGSVRFDYAGCLECGTCRILGLGAALEQWEYPRGTFGVEFRYG"
     gene            complement(21242..22528)
                     /locus_tag="IRB70_002492"
     CDS             complement(21242..22528)
                     /locus_tag="IRB70_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBC0632395.1"
                     /translation="MSEDIFDAIIVGAGLAGSVAALVLAREGAQVLVIERGNSAGAKN
                     VTGGRLYAHSLEHIIPGFADSAPVERLITHEKLAFMTEKSVMTMDYCNGDETSPSQRS
                     YSVLRSKFDAWLMEQAEEAGAQLITGIRVDNLVQRDGKVVGVEADGDVIEAKTVILAD
                     GVNSILAEKLGMAKRVKPTDVAVGVKELIELPKSVIEDRFQLQGNQGAACLFAGSPTD
                     GLMGGGFLYTNENTLSLGLVCGLHHLHDAKKSVPQMLEDFKQHPAVAPLIAGGKLVEY
                     SAHVVPEAGINMLPELVGDGVLIAGDAAGMCMNLGFTIRGMDLAIAAGEAAAKTVLSA
                     MKSDDFSKQKLAEYRQHLESGPLRDMRMYQKLPAFLDNPRMFSGYPELAVGVARDLFT
                     IDGSAPELMRKKILRHGKKVGFINLIKDGMKGVTVL"
     gene            complement(22579..23520)
                     /locus_tag="IRB70_002493"
     CDS             complement(22579..23520)
                     /locus_tag="IRB70_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit
                     alpha/FixB family protein"
                     /protein_id="HBC0632396.1"
                     /translation="MNTFSQVWVFSDTPSRLPELMNGAQALANQINAFVLNDADGAQA
                     IQLGANHVWKLNGKPDDRMIEDYAGVMADTIRQHGADGLVLLPNTRRGKLLAAKLGYR
                     LKAAVSNDASTVSVQDGKATVKHMVYGGLAIGEERIATPYAVLTISSGTFDAAQPDAS
                     RTGETHTVEWQAPAVAITRTATQARQSNSVDLDKARLVVSVGRGIGSKDNIALAEQLC
                     KAIGAELACSRPVAENEKWMEHERYVGISNLMLKPELYLAVGISGQIQHMVGANASQT
                     IFAINKDKNAPIFQYADYGIVGDAVKILPALTAALAR"
     gene            complement(23535..24305)
                     /locus_tag="IRB70_002494"
     CDS             complement(23535..24305)
                     /locus_tag="IRB70_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414583.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein FixA"
                     /protein_id="HBC0632397.1"
                     /translation="MKIITCYKCVPDEQDIAVNNADGSLDFSKADAKISQYDLNAIEA
                     ACQLKQQAAEAQVTALSVGGKALTNAKGRKDVLSRGPDELIVVIDDQFEQALPQQTAS
                     ALAVAAQKAGFDLILCGDGSSDLYAQQVGLLVGEILNIPAVNGVSKIISLTADTLTVE
                     RELEDETETLSIPLPAVVAVSTDINSPQIPSMKAILGAAKKPVQVWSAADIGFNAVDA
                     WSEQQVAAPKQRERQRIVIEGDGEEQIAAFAENLRKVI"
     gene            24779..26293
                     /gene="caiT"
                     /locus_tag="IRB70_002495"
     CDS             24779..26293
                     /gene="caiT"
                     /locus_tag="IRB70_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705996.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine/gamma-butyrobetaine antiport BCCT
                     transporter"
                     /protein_id="HBC0632398.1"
                     /translation="MKNEKRKTGIEPKVFFPPLIIVGILCWLTVRDLDAANVVINAVF
                     SYVTNVWGWAFEWYMVVMLFGWFWLVFGPYAKKRLGNEPPEFSTASWIFMMFASCTSA
                     AVLFWGSIEIYYYISTPPFGLEPNSTGAKELGLAYSLFHWGPLPWATYSFLSVAFAYF
                     FFVRKMEVIRPSSTLVPLVGEKHAKGLFGTIVDNFYLVALIFAMGTSLGLATPLVTEC
                     MQWLFGIPHTLQLDAIIITCWIILNAICVACGLQKGVRIASDVRSYLSFLMLGWVFIV
                     SGASFIMNYFTDSVGMLLMYLPRMLFYTDPIAKGGFPQGWTVFYWAWWVIYAIQMSIF
                     LARISRGRTVRELCFGMVMGLTASTWILWTVLGSNTLLLMDKNIINIPNLIEQYGVAR
                     AIIETWAALPLSTATMWGFFILCFIATVTLVNACSYTLAMSTCREVRDGEEPPLLVRI
                     GWSILVGIIGIVLLALGGLKPIQTAIIAGGCPLFFVNIMVTLSFIKDAKQNWKD"
     gene            26324..27466
                     /gene="caiA"
                     /locus_tag="IRB70_002496"
     CDS             26324..27466
                     /gene="caiA"
                     /locus_tag="IRB70_002496"
                     /EC_number="1.3.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA dehydrogenase"
                     /protein_id="HBC0632399.1"
                     /translation="MDFNLNDEQELFVAGIRELMASENWEAYFAECDRDSVYPERFVK
                     ALADMGIDSLLIPEEHGGLDAGFVTLAAVWMELGRLGAPTYVLYQLPGGFNTFLREGT
                     QEQIDKIMAFRGTGKQMWNSAITEPGAGSDVGSLKTTYTRRNGKIYLNGSKCFITSSA
                     YTPYIVVMARDGASPDKPVYTEWFVDMSKPGIKVTKLEKLGLRMDSCCEITFDDVELD
                     EKDMFGREGNGFNRVKEEFDHERFLVALTNYGTAMCAFEDAARYANQRVQFGEAIGRF
                     QLIQEKFAHMAIKLNSMKNMLYEAAWKADNGTITSGDAAMCKYFCANAAFEVVDSAMQ
                     VLGGVGIAGNHRISRFWRDLRVDRVSGGSDEMQILTLGRAVLKQYR"
     gene            27595..28812
                     /gene="caiB"
                     /locus_tag="IRB70_002497"
     CDS             27595..28812
                     /gene="caiB"
                     /locus_tag="IRB70_002497"
                     /EC_number="2.8.3.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-carnitine CoA-transferase"
                     /protein_id="HBC0632400.1"
                     /translation="MDHLPMPKFGPLAGLRVVFSGIEIAGPFAGQMFAEWGAEVIWIE
                     NVAWADTIRVQPNYPQLSRRNLHALSLNIFKDEGREAFLKLMETTDIFIEASKGPAFA
                     RRGITDEVLWQHNPKLVIAHLSGFGQYGTEEYTNLPAYNTIAQAFSGYLIQNGDVDQP
                     MPAFPYTADYFSGLTATTAALAALHKVRETGKGESIDIAMYEVMLRMGQYFMMDYFNG
                     GEMCPRMSKGKDPYYAGCGLYKCADGYIVMELVGITQIEECFKDIGLAHLLGTPEIPE
                     GTQLIHRIECPYGPLVEEKLDAWLAAHTIAEVKERFAELNIACAKVLTVPELESNPQY
                     VARESITQWQTMDGRTCKGPNIMPKFKNNPGQIWRGMPSHGMDTAAILKNIGYSENDI
                     QELVSKGLAKVED"
     gene            28886..30439
                     /gene="caiC"
                     /locus_tag="IRB70_002498"
     CDS             28886..30439
                     /gene="caiC"
                     /locus_tag="IRB70_002498"
                     /EC_number="6.2.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308067.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetaine/carnitine-CoA ligase"
                     /protein_id="HBC0632401.1"
                     /translation="MDIIGGQHLRQMWDDLADVYGHKTALICESSGGVVNRYSYLELN
                     QEINRTANLFYTLGIRKGDKVALHLDNCPEFIFCWFGLAKIGAIMVPINARLLREESA
                     WILQNSQACLLVTSAQFYPMYQQIQQEDATQLRHICLTDVALPADDGVSSFTQLKNQQ
                     PATLCYAPPLSTDDTAEILFTSGTTSRPKGVVITHYNLRFAGYYSAWQCALRDDDVYL
                     TVMPAFHIDCQCTAAMAAFSAGATFVLVEKYSARAFWGQVQKYRATITECIPMMIRTL
                     MVQPPSANDRQHRLREVMFYLNLSEQEKDAFCERFGVRLLTSYGMTETIVGIIGDRPG
                     DKRRWPSIGRAGFCYEAEIRDDHNRPLPAGEIGEICIKGVPGKTIFKEYFLNPKATAK
                     VLEADGWLHTGDTGYCDEEGFFYFVDRRCNMIKRGGENVSCVELENIIATHPKIQDIV
                     VVGIKDSIRDEAIKAFVVLNEGETLSEEEFFRFCEQNMAKFKVPSYLEIRKDLPRNCS
                     GKIIRKNLK"
     gene            30548..31333
                     /gene="caiD"
                     /locus_tag="IRB70_002499"
     CDS             30548..31333
                     /gene="caiD"
                     /locus_tag="IRB70_002499"
                     /EC_number="4.2.1.149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crotonobetainyl-CoA hydratase"
                     /protein_id="HBC0632402.1"
                     /translation="MSESLHLTRNGSILEITLDRPKANAIDAKTSFEMGEVFLNFRDD
                     PQLRVAIITGAGEKFFSAGWDLKAAAEGEAPDADFGPGGFAGLTEIFNLDKPVIAAVN
                     GYAFGGGFELALAADFIVCADNASFALPEAKLGIVPDSGGVLRLPKILPPAIVNEMVM
                     TGRRMGTEEALRWGIVNRVVSQAELMDNARELAQQLVNSAPLAIAALKEIYRTTSEMP
                     VEEAYRYIRSGVLKHYPSVLHSEDAVEGPLAFAEKRDPVWKGR"
     gene            31339..31929
                     /gene="caiE"
                     /locus_tag="IRB70_002500"
     CDS             31339..31929
                     /gene="caiE"
                     /locus_tag="IRB70_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine operon protein CaiE"
                     /protein_id="HBC0632403.1"
                     /translation="MSYYAFEGLIPVVHPTAFVHPSAVLIGDVIVGAGVYIGPLASLR
                     GDYGRLIVQAGANIQDGCIMHGYCDTDTIVGENGHIGHGAILHGCVIGRDALVGMNSV
                     IMDGAVIGEESIVAAMSFVKAGFHGEKRQLLMGTPARAVRSVSDDELHWKRLNTKEYQ
                     DLVGRCHASLHETQPLRQMEENRPRLQGTTDVTPKR"
     gene            complement(32015..32410)
                     /gene="caiF"
                     /locus_tag="IRB70_002501"
     CDS             complement(32015..32410)
                     /gene="caiF"
                     /locus_tag="IRB70_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414576.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carnitine metabolism transcriptional regulator
                     CaiF"
                     /protein_id="HBC0632404.1"
                     /translation="MCEGYVEKPLYLLIAEWMMAENRWVIAREISIHFDIEHSKAVNT
                     LTYILSEVAEISCEVKMIPNKLEGRGCQCQRLVKVVDIDEQIYARLRNNSRDKLVGVR
                     KTPRIPAVPLTELNREQKWQMMLSKSMRR"
     gene            complement(32671..35892)
                     /gene="carB"
                     /locus_tag="IRB70_002502"
     CDS             complement(32671..35892)
                     /gene="carB"
                     /locus_tag="IRB70_002502"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBC0632405.1"
                     /translation="MPKRTDIKSILILGAGPIVIGQACEFDYSGAQACKALREEGYRV
                     ILVNSNPATIMTDPEMADATYIEPIHWEVVRKIIEKERPDAVLPTMGGQTALNCALEL
                     ERQGVLEEFGVTMIGATADAIDKAEDRRRFDVAMKKIGLETARSGIAHTMEEALAVAA
                     DVGFPCIIRPSFTMGGSGGGIAYNREEFEEICARGLDLSPTKELLIDESLIGWKEYEM
                     EVVRDKNDNCIIVCSIENFDAMGIHTGDSITVAPAQTLTDKEYQIMRNASMAVLREIG
                     VETGGSNVQFAVNPKNGRLIVIEMNPRVSRSSALASKATGFPIAKVAAKLAVGYTLDE
                     LMNDITGGRTPASFEPSIDYVVTKIPRFNFEKFAGANDRLTTQMKSVGEVMAIGRTQQ
                     ESLQKALRGLEVGATGFDPKVSLDDPEALTKIRRELKDAGAERIWYIADAFRAGLSVD
                     GVFNLTNIDRWFLVQIEELVRLEEKVAEVGITGLNAEFLRQLKRKGFADARLAKLAGV
                     REAEIRKLRDQYDLHPVYKRVDTCAAEFATDTAYMYSTYEEECEANPSTDREKIMVLG
                     GGPNRIGQGIEFDYCCVHASLALREDGYETIMVNCNPETVSTDYDTSDRLYFEPVTLE
                     DVLEIVRIEKPKGVIVQYGGQTPLKLARALEAAGVPVIGTSPDAIDRAEDRERFQHAV
                     ERLKLKQPANATVTAIEMAVEKAKEIGYPLVVRPSYVLGGRAMEIVYDEADLRRYFQT
                     AVSVSNDAPVLLDHFLDDAVEVDVDAICDGEMVLIGGIMEHIEQAGVHSGDSACSLPA
                     YTLSQEIQDVMRQQVQKLAFELQVRGLMNVQFAVKNNEVYLIEVNPRAARTVPFVSKA
                     TGVPLAKVAARVMAGKSLAEQGVTKEVIPPYYSVKEVVLPFNKFPGVDPLLGPEMRST
                     GEVMGVGRTFAEAFAKAQLGSNSTMKKHGRALLSVREGDKERVVDLAAKLLKQGFELD
                     ATHGTAIVLGEAGINPRLVNKVHEGRPHIQDRIKNGEYTYIINTTSGRRAIEDSRVIR
                     RSALQYKVHYDTTLNGGFATAMALNADATEKVISVQEMHAQIK"
     gene            complement(35910..37058)
                     /gene="carA"
                     /locus_tag="IRB70_002503"
     CDS             complement(35910..37058)
                     /gene="carA"
                     /locus_tag="IRB70_002503"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBC0632406.1"
                     /translation="MIKSALLVLEDGTQFHGRAIGATGSAVGEVVFNTSMTGYQEILT
                     DPSYSRQIVTLTYPHIGNVGTNDADEESSQVHAQGLVIRDLPLIASNFRNTEDLSSYL
                     KRHNIVAIADIDTRKLTRLLREKGAQNGCIIAGDNPDAALALEKARAFPGLNGMDLAK
                     EVTTAEAYSWTQGSWTLTGGLPEAKKEDELPFHVVAYDFGAKRNILRMLVDRGCRLTI
                     VPAQTSAEDVLKMNPDGIFLSNGPGDPAPCDYAITAIQKFLETDIPVFGICLGHQLLA
                     LASGAKTVKMKFGHHGGNHPVKDVEKNVVMITAQNHGFAVDEATLPANLRVTHKSLFD
                     GTLQGIHRTDKPAFSFQGHPEASPGPHDAAPLFDHFIELIEQYRKTAK"
BASE COUNT         8980 a        10077 c         9668 g         8654 t
ORIGIN      
        1 gctgcgattt tgtaggccgg ataagcaaag cgcatccggc attcaacgcc tgatgcgacg
       61 ctggcgcgtc ttatcaggcc tacacgctgc gattttgtag gccggataag caaagcgcat
      121 ccggcacgaa ggagtcaaca tgttagaaga tctcaaacgc caggtattag aagccaacct
      181 ggcgctgcca aaacacaacc tggtcacgct cacatggggc aacgtcagcg ccgttgatcg
      241 cgagcgcggc gtctttgtga tcaaaccttc cggcgtcgat tacagcgtca tgaccgctga
      301 cgatatggtc gtggttagca tcgaaaccgg tgaagtggtt gaaggtacga aaaagccctc
      361 ctccgacacg ccaactcacc ggctgctcta tcaggcattc ccctccattg gcggcattgt
      421 gcatacgcac tcgcgccacg ccaccatctg ggcgcaggcg ggtcagtcga ttccagcaac
      481 cggcaccacc cacgccgact atttctacgg caccattccc tgcacccgca aaatgaccga
      541 cgcagaaatc aacggcgaat atgagtggga aaccggtaac gtcatcgtag aaacctttga
      601 aaaacagggt atcgatgcag cgcaaatgcc cggcgttctg gtccattccc acggcccgtt
      661 tgcatggggc aaaaatgccg aagatgcggt gcataacgcc atcgtgctgg aagaggtcgc
      721 ttatatgggg atattctgcc gtcagttagc gccgcagtta ccggatatgc agcaaacgct
      781 gctggataaa cactatctgc gtaagcatgg cgcgaaggca tattacgggc agtaatgact
      841 gtataaaacc acagccaatc aaacgaaacc aggctatact caagcctggt tttttgatgg
      901 attttcagcg tggcgcaggc aggttttatc ttaacccgac actggcggga caccccgcaa
      961 gggacagaag tctccttctg gctggcgacg gacaacgggc cgttgcaggt tacgcttgca
     1021 ccgcaagagt ccgtggcgtt tattcccgcc gatcaggttc cccgcgctca gcatattttg
     1081 cagggtgaac aaggctttcg cctgacaccg ctggcgttaa aggattttca ccgccagccg
     1141 gtgtatggcc tttactgtcg cgcccatcgc caattgatga attacgaaaa gcgcctgcgt
     1201 gaaggtggcg ttaccgtcta cgaggccgat gtgcgtccgc cagaacgcta tctgatggag
     1261 cggtttatca cctcaccggt gtgggtcgag ggtgatatgc acaatggcac tatcgttaat
     1321 gcccgtctga aaccgcatcc cgactatcgt ccgccgctca agtgggtttc tatagatatt
     1381 gaaaccaccc gccacggtga gctgtactgc atcggcctgg aaggctgcgg gcagcgcatc
     1441 gtttatatgc tggggccgga gaatggcgac gcctcctcgc ttgatttcga actggaatac
     1501 gtcgccagcc gcccgcagtt gctggaaaaa ctcaacacct ggtttgccaa ctacgatcct
     1561 gatgtgatca tcggttggaa cgtggtgcag ttcgatctgc gaatgctgca aaaacatgcc
     1621 gagcgttacc gtcttccgct gcgtcttggg cgcgataata gcgagctgga gtggcgcgag
     1681 cacggcttta aaaacggcgt cttttttgcc caggctaaag gtcggctaat tatcgacggt
     1741 atcgaggcgc tgaaatccgc gttctggaat ttctcttcat tctcgctgga aactgtcgct
     1801 caggagctat taggcgaagg aaaatctatc gataacccgt gggatcgaat ggacgaaatt
     1861 gaccgccgtt tcgccgaaga taaacctgcg ctggcaactt ataacctgaa agattgcgag
     1921 ctggtgacgc agatcttcca caaaactgaa atcatgccat ttttactcga acgggcaacg
     1981 gtgaacggcc tgccggtgga ccgacacggc ggttcggtgg cggcatttgg tcatctctat
     2041 tttccgcgaa tgcatcgcgc tggttatgtc gcgcctaatc tcggcgaagt gccgccgcac
     2101 gccagccctg gcggctacgt gatggattca cggccagggc tttatgattc agtgctggtg
     2161 ctggactata aaagcctgta cccgtcgatc atccgcacct ttctgattga tcccgtcggg
     2221 ctggtggaag gcatggcgca gcctgatcca gagcacagta ccgaaggttt tctcgatgcc
     2281 tggttctcgc gagaaaaaca ttgcctgccg gagattgtga ctaacatctg gcacgggcgc
     2341 gatgaagcca aacgccaggg taacaaaccg ctgtcgcagg cgctgaaaat catcatgaat
     2401 gccttttatg gcgtgctcgg caccaccgcc tgccgcttct tcgatccgcg gctggcatcg
     2461 tcgatcacca tgcgtggtca tcagatcatg cggcaaacca aagcgttgat tgaagcacag
     2521 ggctacgacg ttatctacgg cgataccgac tcaacgtttg tctggctgaa aggcgcacat
     2581 tcggaagaag aagcggcgaa aatcggtcgt gcactggtgc agcacgttaa cgcctggtgg
     2641 gcggaaacgc tgcaaaaaca acggctgacc agcgcattag aactggagta tgaaacccat
     2701 ttctgccgtt ttctgatgcc aaccattcgc ggagccgata ccggcagtaa aaagcgttat
     2761 gccggactga ttcaggaggg cgacaagcag cggatggtgt ttaaagggct ggaaaccgtg
     2821 cgcaccgact ggacgccgct ggcccagcag tttcagcagg agctatacct gcgcatcttc
     2881 cgcaacgagc catatcagga atatgtacgc gaaaccatcg acaaactgat ggcgggtgaa
     2941 ctggatgcgc gactggttta ccgtaaacgc cttcgccgtc cgctgagcga gtatcagcgt
     3001 aatgtgccgc ctcatgtacg cgccgctcgc cttgccgatg aagaaaacca aaagcgtggt
     3061 cgccccttgc aatatcagaa tcgcggcacc attaagtacg tatggaccac caacggcccg
     3121 gagccgctgg actaccaacg ttcaccactg gattacgaac actatctgac ccgccagcta
     3181 caacccgtgg cggagggaat actccctttt attgaggata attttgctac acttatgacc
     3241 gggcaacttg ggctattttg agcaaaaaaa agagttcgcc agataccatt ttgatgcgtg
     3301 acgaatgctt tgccatccag taccatagcg ccctttccat tcctggacct gaataacacc
     3361 actacctcat aagcacggta gcgggtggtt attgcctgca attaaagata tagagccgaa
     3421 cacatatgcc ttttacactt ggtcaacgct ggatcagcga tacagaaagc gaattgggac
     3481 ttggaaccgt tgtcgcggtg gatgcgcgaa ctgtcacttt acttttccca tctactggtg
     3541 aaaaccgtct gtacgcacgc agtgattccc ccgtgacccg cgtgatgttc aaccctggtg
     3601 ataccattac cagccatgac ggctggcaga tgcaagtcga agaagtaaaa gaagaaaatg
     3661 gcttgctgac ctatatcggt actcgcctgg atactgaaga gtccggcgta gccctgcgtg
     3721 aagttttcct tgatagcaaa ctggtgttca gcaaaccgca ggaccgtctg tttgccgggc
     3781 agattgaccg tatggaccgc tttgcgctgc gttatcgcgc gcgtaaatat tccagcgaac
     3841 agttccgtat gccgtacagc ggcctgcgcg gtcagcgtac cagcctgatc ccgcatcagc
     3901 tcaacatcgc tcatgatgtt ggtcgccgcc acgcgccgcg cgtcctgctg gctgacgaag
     3961 tgggtttagg gaaaaccatt gaagccggga tgatcctgca tcagcaactg ctctctggcg
     4021 ctgctgaacg tgtgctaatt atcgtcccgg aaaccttaca gcatcagtgg ctggtagaaa
     4081 tgctgcgccg tttcaacctg cgctttgcgc tatttgatga tgagcgttat gccgaagctc
     4141 agcacgatgc ttacaacccg tttgacaccg aacagctggt gatttgctcg ctggattttg
     4201 cccgtcgtag caaacagcgc ctggaacatc tctgtgaagc cgaatgggac ctgctggtgg
     4261 tcgatgaagc gcatcacctg gtgtggagcg aagatgcgcc aagccgtgaa tatcaggcca
     4321 ttgaacaact ggcagagcac gtgccgggcg ttctgctgct gaccgcgacc ccggaacagc
     4381 tggggatgga aagccacttc gcccgtctgc gtctgctgga cccgaaccgt ttccacgatt
     4441 ttgcgcagtt cgttgaagag cagaaaaatt atcgtccggt tgcggacgcc gttgccatgc
     4501 tgctggcagg taacaaactg agcaatgacg aactgaacat gctcggcgag atgatcggcg
     4561 agcaggatat cgagccgctg ttgcaggcag caaacagcga cagcgaagat gcccagagcg
     4621 cccgtcagga gctggtttcg atgctgatgg atcgccacgg caccagccgc gtgctgttcc
     4681 gtaacacgcg taacggtgtg aaaggattcc cgaaacgcga gctgcacacc attaagctgc
     4741 cgctaccgac gcagtatcag acggctatta aagtctccgg cattatgggc gcacgtaaaa
     4801 gtgcggaaga tcgtgctcgc gatatgctct acccggagcg tatttatcag gaatttgaag
     4861 gtgataacgc cacctggtgg aacttcgatc cgcgcgttga gtggctgatg ggctacctga
     4921 ccagccatcg ctctcagaaa gtgctggtga tctgcgccaa agctgccact gcgctgcaac
     4981 tggagcaggt actgcgcgaa cgtgaaggta ttcgcgctgc ggtgttccac gaaggtatgt
     5041 cgattatcga acgtgaccgc gctgccgcct ggtttgccga agaagacacc ggcgcacagg
     5101 tactgctgtg ctcagaaatc ggttctgaag gacgtaactt ccagttcgcc agccacatgg
     5161 tgatgtttga cctgccattc aacccggatc tactggagca gcgtattggt cgtctggatc
     5221 gtatcggcca ggcgcacgat attcagatcc atgtgcctta tctggagaaa accgctcagt
     5281 cggtgctggt gcgctggtat cacgaaggtc tggatgcatt tgagcacacc tgcccgaccg
     5341 gacgcactat ttacgatagc gtatacaacg atctgattaa ctatctggct tcaccggatc
     5401 aaaccgaagg ctttgacgat ctgatcaaaa actgccgcga gcaacatgaa gcgctgaaag
     5461 cacagctgga acagggtcgt gaccgcctgc tggaaatcca ctccaacggt ggcgaaaaag
     5521 cccaggcact ggcagaaagc attgaagagc aggatgacga taccaacctg atcgccttcg
     5581 ccatgaacct gttcgatatt atcggtatca atcaggacga tcgcggcgac aacatgatcg
     5641 tgctgacgcc gtccgatcat atgctggtgc cggacttccc tggcctgtcg gaagatggca
     5701 tcaccatcac ctttgatcgt gaagtggcgc tggcgcgtga agatgcacag tttattacct
     5761 gggagcatcc gctgatccgc aacggtctgg atctgatcct ttctggcgat accggtagca
     5821 gcacgatttc actgttaaaa aacaaagcgt tgccggtagg tacgctgttg gtggaactga
     5881 tttatgtggt tgaagcccag gctccgaagc agttgcagct caaccgcttc ctgccaccga
     5941 cgccggtacg tatgctgctg gataaaaacg gcaacaacct ggcggcgcag gtagagtttg
     6001 aaacctttaa ccgccagctt aacgcggtta accgtcacac cggcagcaaa ctggttaacg
     6061 ccgtgcagca ggatgttcac gctatccttc aactgggtga agcgcagatc gagaaatctg
     6121 cccgtgcatt gattgatgca gcgcgtaacg aagccgacga aaaactgtct gccgagctgt
     6181 ctcgtctgga agctctgcgt gcagtgaacc cgaacattcg tgacgacgaa ctgaccgcca
     6241 ttgagagcaa ccgtcagcag gtaatggaaa gcctggatca ggcaggttgg cgtctggatg
     6301 ccctgcgttt gatcgttgta acgcatcagt aacggagccg aaaatgggga tggaaaacta
     6361 caatccaccg caggaaccct ggttggttat cctgtatcag gatgaccata ttatggtggt
     6421 caacaagccg agcggtttgt tgtcagtgcc gggtcgtctg gaagagcaca aagacagcgt
     6481 gatgacgcgc attcagcgtg attatccgca ggcagaatcg gtgcatcgtc tggatatggc
     6541 taccagcggc gtgattgtag tggcgctgac caaagccgcg gagcgggagt taaaacgcca
     6601 gttccgcgag cgcgagccga aaaagcagta tgtggcccgc gtctgggggc atccatcccc
     6661 cgcagaaggt ctggtggatc tgccgctgat ttgcgactgg ccaaaccgcc cgaaacagaa
     6721 agtctgttac gaaacgggta aacctgcgca gacggaatat gaagtggtgg agtatgcggc
     6781 ggataacacg gcaagagtgg tgttaaaacc gattaccggg cgttcgcatc aattgcgtgt
     6841 gcatatgctg gcgctgggtc atccgattct cggcgatcgt ttttatgcat caccagaagc
     6901 gagagcgatg gcaccacgtt tgttgctaca tgcagagatg ttgacgatta cccatccggc
     6961 gtatggcaat agtatgacgt ttaaagcgcc agcggatttt taacctttcc tgtacgttta
     7021 taccctcatc ctaagggctg cctcttgtac ataaatcccc gagtccgggg attttttgtt
     7081 tctgccaaac tgctttcagt tgttgcgtgt ggctacgctt tccattcggt aattcccttc
     7141 ctgctccaca gcgaattttt gaactttttc ttcacccgtt gaccgtctct tatatttcat
     7201 tttaacgggt ctgttatggt cctttctgat tgttattcat gggctaatta gcagtctggt
     7261 tggcgatgcc catctcggtg atccgtgtcc tgcacgacgc cttgcgtcac tagcctcttc
     7321 tctagctcat catgcaggtc tttctaattg tgaaatcatc ccacgctact gctaaggttg
     7381 aaggggcgtt ccagcccctt caaccttagc ttattctggc tcattcaata attgcgttgt
     7441 cagtaatttg ttcagcagta cttttttagt agcaacttct tcagtagcaa ctcctttagt
     7501 atcaattttt ttggggggga ttttattaat aataattacc tcatcatata gggaggtagc
     7561 accgttcacg gtagcaccgt ccaggatagc accgtccggg gtagcaccgt ccaggatagc
     7621 accgtccggg gtagcaccgt ccggggtagc accgcccagg ttagcattcc acccaggtct
     7681 ctcataaagg atatcattgc tacctttcat tgttttttta ccaaggtaac aatccctcat
     7741 gtcaacgccg ggaaggtaag cctttctaag atcaacgccc aagttacctt ggcccttatg
     7801 cagctgcaac gtctgagtac atatcttatt cttttcaatg aaaaaagtga cacttaactc
     7861 gatatccccg aaggtctggg cgacccagcg catattgccc tttgcgacca actcatccgg
     7921 attttttgcg catgttttaa gtttattgaa taattccagg ctattgataa acttttctct
     7981 ctcattctcg ttgatagccc cagtaaagta ttctgaggcg ttgatgttgc cagtctggtt
     8041 attcacgaaa ttgaacagaa gtttataagc ctcagtctgt ttatctgacc agaacagatg
     8101 gcgtaacgtc tcccacaagc gttgaaagat attcatcttc acgtccatct tgtccccgct
     8161 caccatctta taaatatcgt tcttgctcat atttaaaagt gtaaccggca tgcctggaac
     8221 tgatactttc atggtaatag cctcgcattg agttaaaaac tcatgatgcg cgttctgaat
     8281 aaatatactt tcaaaaatcg ctcattcagg tatgtgtttt ttatttttaa gacgtaaaaa
     8341 tataattccg ctcgtcgtaa agctctcaac cttaagcagg gtcaacgcga taaaacctac
     8401 agaacccctc ccgtaaaccg tgcattgagc ctgtccacca ttctgagtaa acgccttttc
     8461 tcaaagaagt gaccgccagg gcggccacct ttaatcgtgg gcagttactc agcatcattt
     8521 acagggtcat ttaaaccctt tctgctgctt tatcagctca tatgcctgct gaatttcctg
     8581 cgctttctgc ttcgccatct ccatcatctc aggcggcaaa cctttcgcca ccagcttatc
     8641 gggatggtgt tcactcatca gcttacggta ggcacgtttg atggtggtcg catcatccgt
     8701 cggcttcacg cccagcacat tacaggcatc ttccagcgtt gggccacgct gcgcttgctg
     8761 ccagttacca ccgccagttt gctgctgata accgccgcca aactgtgcac cgccctgcat
     8821 catgcgcaaa aactggtcaa actgagcgcg ggagatccct aattcttctg caatgacata
     8881 cagcaccgcc cgttcattcg ggtgcagtga accatcagca aacgccgcct gaatctggat
     8941 ctccagaaac atacgaatta agtcaaaacg accaaagcag acactgcgaa actggcgcat
     9001 cttttcgcgc agcgggtaat tgtctgattt tcccacccgg aacgcatttt gcgccgcagt
     9061 acgggaagcg ccatgaagat tcattcggtc catcaactgg ctggcgatat gaatatcagc
     9121 ctccgtgacg cgacctttgg atttggttaa atgccccatc acttcaaaag tggtggcaaa
     9181 aaacagcgcc tgacgctcac gctggttggc gaaccacgcc attttacggc tacgggcttt
     9241 atcaaacata tggccaatta acaggcctaa cactacgccc caaaagccgc cgcccatcag
     9301 taaggccacg gccacgccaa tgatttttcc ccaatactgc atatattccc caaatcgaca
     9361 cacggatatc agggctatct cccacaatat aaaggtgctt ttaccgtttt ccggctgcgg
     9421 tcaattgtgg gacatcgcct ataatttgca ttatcatacc tgtcattcaa tgccgtgcct
     9481 aacaccactg acgctattcg gacaggatta acactagcgt agagatgacg agtacgttag
     9541 tctctgaccg tttgtcacgc gcaacgttac cgatgatgga acaataaaat caacgtatga
     9601 aaaaacgtat ccccactctc ctggccacca tgattgccac cgccctttat agtcaacagg
     9661 gactggcagc cgacctcgcc tcacagtgca tgttgggcgt gccaagctat gaccgtcctc
     9721 tggtacaggg cgataccaat gacttacccg tgactatcaa tgctgaccac gcgaaagggg
     9781 actacccgga tgacgccgtg tttactggca gcgtggatat catgcagggt aacagccgtc
     9841 tgcaggccga cgaagtgcag ctccatcaaa aagaggcacc aggacaaccg gagccggtac
     9901 gtaccgttga tgcgctcggt aatgtccatt acgacgataa ccaggtgatc ctcaaagggc
     9961 cgaaaggctg ggcgaatctg aacaccaaag ataccaacgt ctgggaaggt gattaccaga
    10021 tggtgggtcg ccagggtcgc ggtaaagcgg acctgatgaa acaacgtggc gaaaaccgct
    10081 ataccattct ggataacggt agctttacct cctgtctgcc gggttctgac acctggagcg
    10141 tggtaggtag cgaaattatt catgaccgcg aagaacaagt tgcggagatc tggaacgccc
    10201 gctttaaggt gggtccggta ccgatctttt atagccccta tttgcagttg ccggtgggtg
    10261 acaaacgtcg ctctggtttc ttgatcccga acgccaagta caccaccacc aactactttg
    10321 agttctacct gccatattac tggaacatcg cgccaaatat ggatgccacc atcacgccgc
    10381 attatatgca tcgtcgtggc aacatcatgt gggagaacga attccgctac ctctcccagg
    10441 cgggcgctgg cttgatggaa ctggactatc tgccttcaga taaagtctat gaagatgaac
    10501 acccgaacga tgacagttca cgtcgttggt tattctactg gaaccactcc ggggtcatgg
    10561 atcaggtgtg gcgtttcaac gtcgactaca ccaaggtcag cgatcctagc tacttcaatg
    10621 atttcgataa caagtacggt tccagtactg acggctacgc aacgcaaaaa ttcagcgttg
    10681 gctatgcggt gcaaaacttc aatgccaccg tttcaaccaa gcagttccag gttttcagcg
    10741 aacagaacac cagtagctac tcggcagagc cgcagttaga cgttaattac taccagaatg
    10801 atgttggtcc gtttgatacg cgtatttacg gccaggcagt gcactttgtt aacaccagag
    10861 acgacatgcc tgaagcaacc cgtgttcacc tggaaccgac catcaatttg ccgctctcta
    10921 ataactgggg cagcatcaat accgaagcga agttgctggc aacccattat cagcaaacca
    10981 atcttgactg gtataactcc agaaacacga ccaagctgga cgaatccgtt aaccgcgtaa
    11041 tgccgcaatt caaagttgac ggcaaaatgg tctttgaacg cgatatggaa atgctggctc
    11101 cgggttatac ccaaacgctg gaaccgcgcg cgcagtattt gtacgtgccg tatcgcgatc
    11161 agagcgacat ctataactac gactcgtctc tgctgcaatc tgactactct ggcctgttcc
    11221 gggaccggac ttacggcggt cttgaccgta ttgcctccgc taaccaggtg acgaccggtg
    11281 tcacatctcg catatatgat gatgctgccg ttgaacgttt taatatttcc gttggtcaaa
    11341 tctactattt cacggagtct cgcactggcg atgacaacat aacatgggag aatgacgaca
    11401 aaacgggttc actggtgtgg gcaggcgata cttactggcg tatctccgag cgttggggat
    11461 tgcgtggcgg gattcagtac gatacacgtc tggataacgt agcgaccagt aactccagca
    11521 ttgaataccg tcgggatgaa gaccgtctgg tacagctgaa ttaccgttac gccagcccgg
    11581 aatatattca ggctacgctg cctaagtact attccactgc tgagcaatat aagaatggta
    11641 tttcgcagat aggtgctgtc gccagctggc caattgccga tcgttggtcc attgttgggg
    11701 cctactacta cgacaccaat gctaacaagc aagccgactc tatgttaggt gtgcaataca
    11761 gctcctgctg ctatgcaatt cgcgtcggtt acgagcggaa gctgaacggt tgggataacg
    11821 ataaacaaca tgcggtatat gacaacgcaa tcggctttaa catcgaactt cgcggcctga
    11881 gctccaacta cggtctgggt acgcaagaga tgctgcgttc gaacattctg ccgtatcaaa
    11941 acactttgtg atttgttgat ttaccacgta atccgcagtg cggttaattg aaatggaaaa
    12001 agtatgaaga actggaaaac gctgcttctc ggtatcgcca tgatcgcgaa taccagtttc
    12061 gctgcccccc aggtagtcga taaagtcgca gccgtcgtca ataacggcgt cgtgctggaa
    12121 agcgacgttg atggattaat gcagtcggta aaactgaacg ctgctcaggc aaggcagcaa
    12181 cttcctgatg acgcgacgct gcgccaccaa atcatggaac gtttgatcat ggatcaaatc
    12241 atcctgcaga tggggcagaa aatgggagtg aaaatctccg atgagcagct ggatcaggcg
    12301 attgctaaca tcgcgaaaca gaacaacatg acgctggatc agatgcgcag ccgtctggct
    12361 tacgatggac tgaactacaa cacctatcgt aaccagatcc gcaaagagat gattatctct
    12421 gaagtgcgta acaacgaggt gcgtcgtcgc atcaccatcc tgccgcagga agtcgaatcc
    12481 ctggcgcagc aggtgggtaa ccaaaacgac gccagcactg agctgaacct gagccacatc
    12541 ctgatcccgc tgccggaaaa cccgacctct gatcaggtga acgaagcgga aagccaggcg
    12601 cgcgccattg tcgatcaggc gcgtaacggc gctgatttcg gtaagctggc gattgctcat
    12661 tctgccgacc agcaggcgct gaacggcggc cagatgggct ggggccgtat tcaggagttg
    12721 cccgggatct tcgcccaggc attaagcacc gcgaagaaag gcgacattgt tggcccgatt
    12781 cgttccggcg ttggcttcca tattctgaaa gttaacgacc tgcgcggcga aagcaaaaat
    12841 atctcggtga ccgaagttca tgctcgccat attctgctga aaccgtcgcc gatcatgact
    12901 gacgaacagg cccgtgtgaa actggaacag attgctgctg atatcaagag tggtaaaacg
    12961 acttttgctg ccgcagcgaa agagttctct caggatccag gctctgctaa ccagggcggc
    13021 gatctcggct gggctacacc agatattttc gatccggcct tccgtgacgc cctgactcgc
    13081 ctgaacaaag gtcaaatgag tgcaccggtt cactcttcat tcggctggca tttaatcgaa
    13141 ctgctggata cccgtaatgt cgataaaacc gacgctgcgc agaaagatcg tgcataccgc
    13201 atgctgatga accgtaagtt ctcggaagaa gcagcaagct ggatgcagga acaacgtgcc
    13261 agcgcctacg ttaaaatcct gagcaactaa tggttaaaac ccaacgtgtt gtgatcactc
    13321 ccggcgagcc cgccgggatt ggcccggact tagttgtcca gcttgcacag cgtgagtggc
    13381 cggtcgaact ggttgtttgt gccgatgcca ctctccttac caaccgggca gcgatgctcg
    13441 gtttgccgct caccctccgc ccttattccc ccaactcccc tgcacaaccg caaactgcgg
    13501 gcacattaac gctacttcct gtcgcgctac gtgcacctgt cactgcgggg cagttagcgg
    13561 ttgaaaatgg gcattatgtg gtggaaacgc tggcgcgagc gtgcgatggt tgtctgaacg
    13621 gcgaatttgc cgcgctgatc acaggtccgg tgcataaagg cgttattaac gacgctggca
    13681 ttccttttac cggtcatacc gagtttttcg aagagcgttc gcaggcgaaa aaggtggtga
    13741 tgatgctggc gaccgaagaa cttcgcgtgg cgctggcaac gacgcattta ccgctgcgcg
    13801 atatcgcaga cgctatcacc cctgcacttt tgcacgaagt gattgctatt ttgcatcacg
    13861 atttgcggac caaatttggt attgccgaac cgcgcattct ggtctgcggg ctgaatccgc
    13921 acgcgggcga aggcggtcat atgggtacgg aagagataga caccattatt ccggtgctca
    13981 atgagctgcg ggcgcagggg atgaaactca acgggccgct gcctgccgat accctgtttc
    14041 agccgaaata tcttgataac gccgacgccg tgctggcgat gtaccacgat cagggtcttc
    14101 ccgtgctaaa ataccagggc ttcgggcgcg gtgtgaacat tacgctgggc ctgcccttta
    14161 ttcgcacatc agtggaccac ggcaccgcgc ttgaactggc gggacgtggc gaagccgatg
    14221 tcggcagttt tattacggcg cttaatctcg ccatcaaaat gattgttaac acccaatgaa
    14281 taatcgagtc caccagggcc acttagcccg taaacgcttc gggcaaaact ttctcaacga
    14341 tcagttcgtg atcgacagca ttgtttctgc cattaacccg caaaagggcc aggcaatggt
    14401 cgaaatcggc cccggtctgg cggcattgac cgagccggtc ggcgaacgtc tggaccagct
    14461 gacggtcatc gaacttgacc gcgatctggc ggcacgtctg caaacgcatc cattcttagg
    14521 cccgaaactg acgatttatc agcaggatgc gatgaccttt aactttggcg aactggccga
    14581 gaaaatgggt cagccgctgc gtgttttcgg caacctgcct tataacatct ccacgccgtt
    14641 gatgttccat ctgtttagct atactgatgc cattgccgac atgcacttta tgttgcaaaa
    14701 agaggtggtg aatcgtctgg ttgcaggacc gaacagcaaa gcgtatggtc gattaagcgt
    14761 catggcgcaa tactattgca acgtgatccc ggtactggaa gttccgccgt cagcctttac
    14821 accaccaccc aaagtggatt ccgccgtcgt gcgcctggtt cctcatgcaa cgatgcctca
    14881 cccggttaaa gatgttcgtg tgttgagccg catcaccacc gaagccttta accagcgtcg
    14941 taaaaccatt cgtaacagcc tcggcaacct gtttagcgtc gaggtgttaa cgggaatggg
    15001 gatcgacccg gcgatgcgag cggaaaatat ctctgtcgcg caatattgcc agatggcgaa
    15061 ctatctggcg gagaacgcgc ctttgcagga gagttaacga tgatcaattc gccccgagtg
    15121 tgtattcagg ttcaaagcgt ctacattgag gcacaatctt cacctgataa tgaacgttac
    15181 gtttttgctt atactgtaac catacgcaat ctggggcgag cgccagtgca gttgttgggg
    15241 cgttactggc tgatcaccaa tggcaatggc cgtgaaaccg aagtccaggg cgaaggagtg
    15301 gttggcgtcc agccacttat cgcgcctggc gaagagtacc agtacaccag cggtgcaatc
    15361 attgaaaccc cgctgggcac catgcagggt cactacgaaa tgatcgatga aaatggcgtc
    15421 cctttcagca tcgacattcc cgtattccga ctcgccgttc ccacactcat tcattaaaag
    15481 aatatggcga cataccttat tggcgacgtt catggttgtt acgatgaact gatcgcattg
    15541 ctgcataaag tagaatttac ccctgggaaa gataccctct ggctgacggg cgatctggtc
    15601 gcgcgcgggc cgggttcgct ggatgttctg cgctatgtga aatccttagg cgacagcgta
    15661 cgtctggtgc tgggcaatca cgatctgcat ctgctggcgg tatttgccgg gatcagccgc
    15721 aataaaccga aagatcgcct gacaccgctg ctggaagcgc cggatgccga cgagctgctt
    15781 aactggctgc gtcgccagcc tttgctgcaa atcgacgaag agaaaaagtt ggtgatggcc
    15841 cacgcaggga tcacgccgca gtgggatcta cagaccgcca aagagtgcgc gcgcgatgta
    15901 gaagcggtgc tatcgagtga ctcctatccc ttctttctcg acgctatgta cggcgatatg
    15961 ccaaataact ggtcaccgga attgcggggg ctgggaagac tgcgttttat caccaacgcc
    16021 tttacccgta tgcgtttttg ctttccaaac ggtcaactgg atatgtacag caaagaatcg
    16081 ccggaagaag cccctgcccc actgaaaccg tggtttgcga ttcctggccc tgtcgctgaa
    16141 gaatacagca tcgcctttgg tcactgggca tcgctggaag gcaaaggtac gccggaaggt
    16201 atttacgcgc tggataccgg ctgctgctgg ggtgggtcat taacctgcct gcgctgggaa
    16261 gataagcagt attttgtcca gccgtcgaac cggcataagg atttgggcga agcggcggcg
    16321 tcttaaacac agcctgatat aggaaggccg gataagacgc gaccggcgtc gcatccggca
    16381 ctagccgtaa attctataca aaattaccgc cgctccagaa tctcaaagca atagctgtga
    16441 gagttctgcg catcagcatc gtggaattcg ctgaataccg attcccagtc atccggctcg
    16501 taatccggga aatgggtgtc gccttccact tctgcatcga tatgcgtcag atacagtttt
    16561 tgcgctttgg gcaggaactg ctcataaacg cgaccgccgc caatcaccat gatttctggt
    16621 acgtcaccac acgccgcgat ggcttcatca accgatttca cccacgttac gcgatcgtcc
    16681 gtacccggtt gactgctgag gataatattt ttgcgtcctg gcagcggacg accgatggat
    16741 tcccaggtat ggcggcccat aatcacgggt ttatttaagg tgttgcgttt aaaccaggcg
    16801 agatcggcag gcaggttcca cggcatggcg ttttccatgc cgataacacg atccaccgct
    16861 aacgccgcaa tcagactaat cattgattta tcctggatat aaaaaattgt cgccactata
    16921 cgtaaagcgt aaaccgtcgt cgactggcgc aaggatgatg ttgaggaaaa ttttacgttc
    16981 tgctggcgag tccacgctct cccactggac tcgccacatt acaatgaaac aaaaacaaac
    17041 agttagctgt aaagtgtgat ttacgtcact ctttattagg atgagggttt cgtttccggt
    17101 tcatccgcca tgttgccggt atgtttccct tcttcggttc cctgccagcc atgtcgttga
    17161 attaatgaca gatgttcgcg gtcttcggta atgatctcac ttaacatcgc gctggtgcgt
    17221 ttatagaccg ctgcgcgggc tttggtgtcg ttctcaacca ttgccatctc ttccaccatc
    17281 tgaatattaa agcggcggaa cacatcggca cgttctcgcg cttcatacgg ccccagacct
    17341 aaactttcca gtgccagacg cccggttttc agcgcacctt cgaaggtttc acgctccggc
    17401 ttttcaacgc ctgcctgacg caaacgaatg tagtgatcga catcgcgggc gcgggcaata
    17461 atctgcaaat gcgggaaatg ttctttcacc atctccgtca gttgcaggtt ggtttgcgga
    17521 tcgtcaattg cgttaatcag cacttccgct ttcgccgctc cggcagactc cagtaaatcc
    17581 atccgcgtgg catcgccata aaacactttc ataccaaatt tacgcaaggt ttcgatatgg
    17641 tccgggtcgt gatcgagcac caccattttc accccgctgg agagcagtaa acgtccggtg
    17701 atctgcccga aacgaccgaa tccggcgata atcacgcgtg gctgttcttc gtcgatctca
    17761 tcggcttcac gcgcttcctc agtagaagat tgctcaaggc gattgaggat caccagcaga
    17821 atcggcgttg ctgccatcga cagcgccacc gccagggtca gcgatttcgc ccactccggc
    17881 tccagcacat tcgccatttg cgctgcacca aataccacaa aggcaaactc actgccctgc
    17941 cctaacagca ccgcaaacca gcgacgctgt ttatttggca cctgcaacgg tcgggcaatc
    18001 agccacagca tggcgatttt gatgatgagg aaaccgagca gcaaaatgac aatgcgcaat
    18061 gggttttcaa gcagcgtgcc aaagtctatc gacatgccaa caccgatgaa aaacagcccc
    18121 aacagcaaac ctttaaatgg ttcgatatcg ctttccagcg catgacggta ttccgagctt
    18181 gccagcagta cgcccgccag aaacgcgccc atcgccatcg ataagccgac ctcttccagc
    18241 agcaaaccaa agccaaacac gaggaataac gccacggcac taaacacttc ccgcaagcca
    18301 gagcgggcaa caaaacgcag cgccggacgt gtgacatagc gccccagcaa taccaccagc
    18361 accagcgcgc ccgccacttt taacgccgag agagcaaatg cgcccatcgt cgtcgaggca
    18421 ctgctcgccg ccagtagcgg gatcatcgcc accagcggga tcgccgcgat atcctggaac
    18481 agcagcaccg caaaggcact gcggcccatc tgcgtcatca tcagattgcg ctcattcatc
    18541 gcctgcatgg caatcgccgt agaggagagc gccagcgtca tgccgatcaa ttccgcgacc
    18601 tgccagcgca gcccaagtaa catgcagaac agccccagca ggccgccgca aatcaccatc
    18661 tgcaatgcgc caccgccgaa cactgccgca cgcagcttcc acagcctttg tggatcgagt
    18721 tcgaggccga taataaacag catcagcacc acgccaatct cggcaaagtg cagaatagat
    18781 tcggcatcgg tcaccagtcg cagcccccac gggccaataa tgcagccagc gatcaggtag
    18841 ccaagtaccg atcccagacc aagacgtacc gcaatgggta caatcagcgc cgccgaaccg
    18901 agataaatca gcgcctgaat cagcgtatgg ctatccatga tgtgcctcct gccattccag
    18961 cagacgttgc ttatagtggc gcgcctgccc ttcgagggtt tcgtcgtcac aaataaaggt
    19021 gcagtgcatg gcaaacggtg gcagccagtt cagcccgcag tagattgccg tcgcctgtag
    19081 cggctgcgac agcacatcaa agcccggatg cgcaccaatt tcaaaatggc tttccccgcc
    19141 gccggtcgtc accgcccaca gcaaatgttt gccatgcagc gccgtgccgc catgaccgta
    19201 agcccagccg tgggagaaaa ctttatcgat ccaaagtttg aggagcggag gaatgctgta
    19261 ccactgcatc gggtgctgcc agacgatcag atcggcgcga gacagcgcct cctgctcggc
    19321 ggcaatatcg atattgaagt caggatagag ttgataaaga gagcgaattt cgacgccttc
    19381 cagcgtcctt gcctgttcaa gcatccgttt attcgcatgg gaatgatgcg gatacggatg
    19441 cgcataaatt ataagaatca taggtagccc gcgtgattac gcctttgttt tcccacaaag
    19501 tgtagtcata tattcacgcg gcttatagtc aataatattg attcagaaaa gagagaaatc
    19561 tgaataaatt accccgctcg ctgcctgcga atcgtcatat tgctggtctg cgccagtgac
    19621 atccctcgag tctccggggc aaacgctacg gaaatcaaca agccaaacag cgagataccc
    19681 gcccccatta gcatcgtgtt actgataccg taattattga taaagatcgg tagtgcccag
    19741 gtcgaaacaa tggtgccaat acgacttaag gacataatca cgcccacggc agaggcgcgg
    19801 atatccgtcg ggaagagttc attaggatag agccactgca aattacccgg cccgccagag
    19861 aaaaaggcat acaccgcaaa ggccatcact accagccaga tccccatatc cgggatcagc
    19921 cccaaaaccg ccagcgccag cgtcatcatg gcaaagctgc caatcaacaa tggacgccgt
    19981 ccggcagtgt ttagccacag catcggcgga atacagccga gcataaagaa caggctaatc
    20041 accacgttcc ccagtgccgc gtttttgcca acacccaatc ccaacaaacc aacgatttgc
    20101 gggccaaagg tgtaaatggc gaacattggg atcacctggc aggtccagat ggcggcaaca
    20161 aacagaacaa aaggaaaatg gcggcgatta aacagatcgc gaaaacgggt ttgctgcggc
    20221 tgctcttcat cgaaagccac cggttcgcca aacagtttga tcatcatctc ttcgcactct
    20281 tttactcgcc ctttgcgtaa cagccagcgg ggagattcag gcagttcgaa tcgaccaatc
    20341 aaaatcaaca aacaggggat cgccgcgcta cccagcatcc agcgccagcc gccttccaca
    20401 tcataaagcc agtagccgac cagatcggca caggtcgcgc cgacatacca catcgcggca
    20461 ataaagctga tggaaaacgc ccgctgacgg gtactggaga actcggtgat catcgaagtg
    20521 gcgatgggat aatctgcacc gatgacaatg ccgatgagta cccgcatcac caacagttcg
    20581 acgggggatg aaacaaacat cgtcgccacc gatattacgc cgatggcgat gatatcaatg
    20641 aggaacattt tgcgccgtcc gactttatcg gagatatagc caaacagcga tgtgccaacg
    20701 aacagcccgg cgagcgttcc cgcgcccagc aagccaatcc agtcagcgtc cagtttcagc
    20761 gccggagtca gttgctccag cgccacgcca atcattacca gtacataacc atccagaaac
    20821 ggaccaccgc ttccccacag caaaatgcgg cggtgaatag aggagaattt gagatcgtca
    20881 aagtttctgg acggttgcat gagttattcc tgttttttgc aatgagagtc agtgcggcgt
    20941 tacgtatcaa accaacatca gccgtaacgg aactccacac caaaggtgcc gcgcgggtat
    21001 tcccactgtt ccagcgccgc ccccagcccc agaatgcgac aggtgccgca ctccagacat
    21061 ccggcgtaat cgaagcgcac actgccgtca tcctgcttct tgtacagacc tgcggggcac
    21121 gctttcacca gcagctccag cacctgttta tcagcatcgg ccttcacaac aatgtgcgga
    21181 tgctcttcat cgacattgaa tttattgacg cccagtttga cgtccacatt gacgggagaa
    21241 gtcataaaac ggtcactcct ttcatgccat ccttgattag attgatgaag cccactttct
    21301 tgccatggcg gaggattttc ttgcgcatca gttccggcgc gctgccatca atggtgaaca
    21361 ggtcacgcgc cacacccacc gccagctccg ggtagccgct aaacatgcgt gggttatcaa
    21421 ggaacgccgg tagtttctgg tacatgcgca tatcgcgcag cgggccactc tcaagatgct
    21481 gacgatattc cgcgagtttt tgcttactga aatcgtcgct tttcatcgct gaaagcacgg
    21541 tttttgctgc ggcttccccg gcggcaatcg ccagatccat accgcgaatg gtaaaaccga
    21601 ggttcataca cattccggcg gcatcaccgg caatcaatac gccgtcacca accaactccg
    21661 gcagcatgtt gatgcctgct tccggcacta cgtgagcgga atattccacc agcttgccac
    21721 ccgcgatcag cggtgcaacg gccggatgtt gtttgaaatc ttccagcatt tgcggcaccg
    21781 attttttcgc gtcatgcaga tgatgcaaac cacaaaccag ccccagcgac agggtgtttt
    21841 cattggtata aaggaagccg ccgcccatca ggccatcggt gggtgatccc gcaaacaggc
    21901 aagccgcccc ctgattaccc tgcaactgaa aacggtcttc aataaccgac ttcggtaact
    21961 cgatcagttc cttcacgcca accgccacat ccgtcggttt aacgcgtttt gccatcccca
    22021 gcttttcggc aaggatggaa ttcaccccgt cagcaaggat caccgttttc gcttcaatca
    22081 catcgccatc ggcttctaca ccgacaactt tgccatcgcg ctgtacgagg ttatcgacgc
    22141 ggatcccggt aattaactgc gcgcccgctt cttcggcctg ctccatcagc caggcatcaa
    22201 atttactgcg taaaacggag taagaacgct gggatggcga ggtttcgtcg ccattgcagt
    22261 agtccatggt catcactgac ttttccgtca taaacgcgag tttttcatgg gtgatcaggc
    22321 gttctacggg ggcggagtcg gcgaaaccag gaataatgtg ttccagactg tgggcataga
    22381 gacgcccgcc ggtgacgttc ttggcacctg cggaattgcc acgctcgata actaacactt
    22441 gcgcaccttc gcgggcgagc accagtgcgg caaccgaacc ggcaagccct gcaccgacga
    22501 tgatggcgtc aaagatatct tcggacataa gagctccctg tcagcgacag ggccgtaatg
    22561 cagccctgcc agagtggatc aacgcgctaa agctgcggtc agcgccggaa ggatcttcac
    22621 ggcgtcgcca acaatgccgt aatccgcgta ctggaagatc ggcgcatttt tatctttgtt
    22681 gatggcgaaa atggtttgcg acgcgttagc gccaaccatg tgctggatct gcccggagat
    22741 ccccaccgcc aggtacagtt caggtttcag catcaggttg gagataccga catagcgttc
    22801 gtgctccatc catttttcgt tttccgccac cggacgagaa caggccaact ccgcacctat
    22861 cgccttacaa agctgttctg ccagcgcaat gttatctttg ctgccaatgc cgcgaccgac
    22921 gctgaccacc agacgggctt tgtcgagatc gacgctgttg ctctggcgcg cctgggttgc
    22981 cgtgcgggta atcgccacag ccggagcctg ccactccacg gtgtgcgttt cgccagtgcg
    23041 tgacgcgtct ggctgagccg catcgaacgt gccgctgctg atggtcagta ccgcatacgg
    23101 cgtggcaatg cgttcttcgc caatcgccag accaccgtaa accatgtgtt tcactgtcgc
    23161 tttaccgtcc tgtacgctga cggtgctggc atcgttagac accgccgctt taaggcgata
    23221 acccagtttt gccgccagta atttgccgcg acgggtgttt ggcaacagca ccaggccgtc
    23281 tgcgccgtgc tggcgaatag tgtcagccat gacaccggcg taatcttcga tcatccgatc
    23341 gtccggtttg ccgtttaatt tccagacatg attagcgccg agctggattg cctgtgcgcc
    23401 gtcggcatca ttgaggacaa aggcattgat ttgattagct aaagcctgcg caccgttcat
    23461 cagttccggc agacgagaag gggtatcgct gaatacccag acttgagaaa acgtgttcat
    23521 agcatcccct gtaattaaat gactttgcga agattttcag caaatgcggc gatctgttct
    23581 tcgccgtcgc cttcaatcac gatgcgctga cgttcgcgct gtttcggcgc ggcaacctgt
    23641 tgttcagacc aggcgtccac ggcgttaaaa ccgatatccg ccgccgacca tacctggact
    23701 ggctttttcg ccgcgccgag aatggctttc atcgaaggaa tttgtgggga gttgatatca
    23761 gtggaaacag caacaaccgc aggcagcgga atgcttaacg tttctgtttc atcttccagt
    23821 tcgcgctcaa cggtgagggt atctgccgtc agggagataa ttttgctgac gccgttaact
    23881 gccggaatat tgaggatttc gcctaccagc aaaccaacct gctgggcata aaggtcggaa
    23941 gaaccatcgc cacagaggat caaatcaaag cctgctttct gggcggcgac agccagtgcg
    24001 ctcgccgttt gttgcggcag tgcctgctcg aactggtcat caatcaccac aatcagttca
    24061 tccggaccgc gcgatagcac atctttacgc cctttggcgt tggtcagggc tttaccgccc
    24121 acacttaagg ccgtcacctg cgcctctgct gcctgttgct ttagctggca agccgcttca
    24181 atagcgttca gatcgtattg gcttattttg gcatcggctt tgctgaagtc taatgaacca
    24241 tcagcattat tgaccgcaat atcctgttca tcaggcacgc acttatagca agtaataatc
    24301 ttcattgcat ctccagaaat catgaaggaa acgtcgttca tatcggtggt gttaattaca
    24361 gatatcacgc cctttaattt ggaaataaaa ctttaatcac caatattgaa aatgtcacac
    24421 gcagataaat ccaactttca atattgttaa gtccctcacc aatattgaaa acatggcgta
    24481 gcaaaaagaa atttccaata ttgttttatg gatcaccaat attgaaagtc agatgctatt
    24541 tttttactca caacagagca taacaaactg attattaatc aaaattaacg aaaaaaacgc
    24601 cctctattca cccgaaacaa aaatgtgata ccaatcacag aatacagctt attgaatacc
    24661 cattatgagt tagccattaa cgcgtccacg aggttaataa taattatatt aaatgttaac
    24721 aaaaataaaa caaacgggaa cgcaaaataa atattcgttt tcacagtgga attaactcat
    24781 gaagaatgaa aagagaaaaa cgggaataga accgaaggtt ttctttccgc cgttaataat
    24841 cgtcggcata ctttgttggc ttacagtcag agatctggat gcagcgaatg tcgttattaa
    24901 tgctgtattc agttacgtca ccaatgtatg gggatgggca tttgaatggt atatggtggt
    24961 gatgcttttc ggttggttct ggctggtgtt tggcccgtat gccaaaaagc gtttaggtaa
    25021 cgaaccacct gaatttagta ccgccagttg gatctttatg atgttcgcct cctgtacgtc
    25081 tgctgccgta ctgttctggg gatcgattga gatctactac tacatctcca ccccgccgtt
    25141 tggcttagaa ccgaactcga caggggcgaa agagttgggg ctggcttaca gcttgttcca
    25201 ctggggacct ctgccgtggg ccacttacag cttcctttca gtcgccttcg cttacttctt
    25261 ctttgtccgc aaaatggaag tgattcgccc cagctcgaca ctggtgccgc tggtaggtga
    25321 aaaacacgcc aaagggttgt tcggcactat cgtcgacaac ttctatctcg tcgccttgat
    25381 cttcgcgatg ggtaccagtt tgggccttgc cacgccgctg gtgaccgagt gtatgcaatg
    25441 gttgtttggc attccgcata ccctgcaact ggacgctatc atcattacct gctggattat
    25501 cctcaacgcc atttgcgtcg cttgcggtct gcaaaaaggg gtacgtatcg ccagtgacgt
    25561 gcgtagttac ctgagcttcc tgatgctggg ttgggtgttc attgtcagcg gtgccagctt
    25621 catcatgaac tacttcaccg attcggtggg gatgttgctg atgtatctgc cgcgaatgtt
    25681 gttctatacc gatcccatcg ctaaaggcgg cttcccgcag ggctggaccg tgttctactg
    25741 ggcatggtgg gtgatttacg ccatccagat gagtatcttc ctcgcccgca tctcccgtgg
    25801 tcgtactgtg cgtgaactgt gcttcggcat ggtgatgggg ctgacagcat ccacctggat
    25861 cctgtggacc gtgctcggta gtaacactct gctgttgatg gataaaaaca tcatcaacat
    25921 tccaaatctg atcgaacagt acggtgtggc gcgcgccatc atcgaaacct gggccgctct
    25981 gccactcagc accgccacca tgtggggctt cttcatcctc tgctttattg ccaccgttac
    26041 gctggttaac gcctgctctt ataccctggc gatgtccact tgccgcgaag tacgcgatgg
    26101 tgaagaacca ccgctgctgg tgcgtatcgg ttggtcaatt ctggttggca ttatcggtat
    26161 tgttctgctg gcgctcggcg gcctgaaacc gattcaaacc gccattatcg ccggaggatg
    26221 cccgctgttc ttcgtcaaca ttatggtgac gctctccttt attaaagacg cgaaacagaa
    26281 ctggaaagat taattaaccc ccaaaatatc aagaggttga aagatggatt ttaatttaaa
    26341 tgatgagcag gaactgtttg tcgccggtat ccgcgaactg atggccagcg aaaactggga
    26401 ggcctatttt gccgagtgcg accgtgacag cgtctacccg gaacgttttg tcaaagcact
    26461 ggcggatatg ggtatcgaca gtctgctgat ccctgaagag cacggtggtc tggacgcggg
    26521 gtttgttact ctcgccgccg tgtggatgga gctgggacgt ctgggggcac caacctatgt
    26581 gctgtaccag ttgccgggcg ggttcaacac cttcctgcgc gaaggcacac aagagcagat
    26641 cgacaagatt atggctttcc gcggcaccgg taagcagatg tggaactcag cgattaccga
    26701 accgggcgcg ggctccgacg tgggtagcct gaaaacgact tatacccgta gaaatggtaa
    26761 gatttatctt aatggtagta agtgttttat taccagcagc gcctataccc cgtacatcgt
    26821 ggtgatggcg cgcgacgggg cttctccgga caaacctgtc tacaccgaat ggtttgttga
    26881 tatgagcaaa ccgggcatca aagtgaccaa acttgaaaag ctcggtctgc gtatggatag
    26941 ctgctgtgaa atcacctttg acgacgtgga actggacgag aaagacatgt tcggtcggga
    27001 aggtaacggc tttaaccgcg tcaaagaaga gttcgaccat gaacgtttcc tggtagccct
    27061 gaccaactac ggtacggcga tgtgcgcctt tgaagatgcg gcgcgctacg ccaaccagcg
    27121 cgtgcagttt ggcgaggcta ttggtcgttt ccagttgatt caggaaaaat tcgcccacat
    27181 ggcgatcaaa ttaaactcca tgaaaaacat gctgtatgaa gcagcgtgga aagcagacaa
    27241 cggcaccatc acctctggcg atgcagcgat gtgcaaatac ttctgcgcca atgcggcatt
    27301 tgaagtggtg gatagcgcaa tgcaggtgct gggcggtgtc gggattgcgg gcaaccaccg
    27361 catcagccgc ttctggcgtg acctgcgtgt agaccgcgtc tccgggggat ctgacgaaat
    27421 gcagatcctg acgctgggtc gtgcggtgct gaagcaatac cgctaagtca atgcgctgcc
    27481 tgatgcgacg ctgatgcgtc ttatcaggcc tacgggagca cgaatgtagg ccggataaag
    27541 cgtttacgcc gcatccggca gtcatgcgct acataaattt ttcaggagca aataatggat
    27601 catctaccca tgccgaaatt cgggccgttg gccggattgc gcgttgtctt ctccggtatc
    27661 gaaatcgccg gaccgtttgc cgggcaaatg ttcgcagaat ggggcgcgga agttatctgg
    27721 atcgagaacg tcgcctgggc cgacaccatt cgcgttcaac cgaactaccc gcaactctcc
    27781 cgccgcaatt tgcacgcgct gtcgttaaat attttcaaag atgaaggccg cgaagcgttt
    27841 ctgaaattaa tggaaaccac cgatatcttc atcgaagcca gtaaaggtcc ggcctttgcc
    27901 cgtcgtggca ttaccgatga agtactgtgg cagcacaacc cgaaactggt tatcgctcac
    27961 ctgtccggtt ttggtcagta cggcaccgag gagtacacca atcttccggc ctataacact
    28021 atcgcccagg cctttagtgg ttacctgatt cagaacggtg atgttgacca gccaatgcct
    28081 gccttcccgt ataccgccga ttacttttct ggcctgaccg ccaccacggc ggcgctggca
    28141 gcactgcata aagtgcgtga aaccggtaaa ggcgaaagta tcgacatcgc catgtatgaa
    28201 gtgatgctgc gtatgggcca gtacttcatg atggattact tcaacggcgg cgaaatgtgc
    28261 ccgcgcatga gcaaaggtaa agatccctac tacgccggtt gcggtctgta taaatgcgcc
    28321 gacggctaca tcgtgatgga actggtgggc attacccaaa ttgaagagtg ctttaaagat
    28381 attggcctcg cacatctact cggtacgccg gaaatcccgg aaggcactca gcttatccac
    28441 cgtatcgaat gcccttacgg cccactggta gaagaaaaac tcgatgcctg gctggcggca
    28501 cataccatcg cagaagttaa agaacgcttt gccgaactga atatcgcctg tgccaaagta
    28561 ctgaccgtac cggaactgga aagcaatcca cagtatgttg cccgtgaatc aatcactcag
    28621 tggcaaacga tggatggtcg cacctgcaaa gggccgaaca tcatgccgaa attcaaaaat
    28681 aaccccggac aaatctggcg cggaatgccc tcacatggca tggacacggc tgccattttg
    28741 aaaaatatcg gctacagcga aaacgacatt caggagttgg tcagcaaagg tctggccaaa
    28801 gttgaggact aaacgcgtgg cgtcagtcgg cttgcctgac tagcgcccgc ccaataacaa
    28861 acgaacaaaa atggatagag gtgcaatgga tatcattggc ggacaacatc tacgtcaaat
    28921 gtgggacgat cttgcggacg tttacggtca taaaacggcg ctgatttgtg aatccagcgg
    28981 cggagtcgtt aaccggtata gttatcttga gttaaatcag gagattaacc gcacggcaaa
    29041 cctgttttat acgctgggga ttcgcaaagg cgacaaggtt gcactacatc tcgacaactg
    29101 cccggaattt atcttttgct ggttcgggct ggcaaaaatt ggcgcgatta tggtgccgat
    29161 taacgcccgc ctgttacgcg aggaaagcgc gtggatcctg caaaatagcc aggcgtgcct
    29221 gctggtgacc agtgcgcaat tctatcctat gtatcaacag attcagcagg aagatgccac
    29281 tcaattgcgg cacatttgcc tgacagatgt ggcacttccc gctgatgatg gcgtgagttc
    29341 gtttactcaa ctgaaaaatc aacaacctgc caccttgtgc tatgcaccgc cgctatcgac
    29401 tgacgatacg gcggaaattc tcttcacctc cggcaccacc tcccgaccga aaggtgtggt
    29461 gattacccat tacaacctgc gcttcgctgg atattactcc gcctggcagt gtgcactgcg
    29521 tgacgatgac gtctacctga cggtaatgcc tgcgtttcat atcgattgcc agtgtactgc
    29581 ggcgatggcg gcgttttctg ccggggccac ctttgtgctg gtcgagaaat acagcgcccg
    29641 cgccttctgg ggacaggtgc agaagtaccg cgccaccatt accgaatgta ttccgatgat
    29701 gatccgtacg ttgatggtgc agccgccttc agcgaacgat cggcaacacc gcctgcggga
    29761 agtgatgttt tatctcaact tgtcggagca ggaaaaagat gcgttttgtg aacgcttcgg
    29821 cgttcgcttg ctgacgtctt atgggatgac ggaaaccatt gtgggcatta tcggcgatcg
    29881 ccctggcgat aaacgacgct ggccgtcgat tggtcgggcg gggttttgct acgaagcgga
    29941 gatccgcgac gatcacaatc gcccgctccc ggcaggtgag atcggtgaaa tctgtattaa
    30001 aggcgtacca gggaaaacca tcttcaaaga gtattttctc aacccgaaag ccactgcgaa
    30061 agtgctggaa gccgacggct ggctacatac cggcgatacc ggatactgcg acgaagaggg
    30121 ctttttttat ttcgtcgatc gccgctgcaa tatgatcaaa cgcggtggcg agaatgtctc
    30181 ctgcgtggag ctggaaaata tcatcgccac ccatccaaaa attcaggata tcgtggttgt
    30241 gggtattaaa gattcgattc gcgatgaagc catcaaagca tttgtggtgc tgaatgaagg
    30301 tgaaacattg agcgaagagg aatttttccg cttctgcgaa caaaatatgg cgaaatttaa
    30361 agtgccctct tatctggaga tcagaaaaga tctgccacgt aattgctcgg ggaaaataat
    30421 tagaaagaat ctgaaataaa tgaaacagca gggaactacc ctgccagcta ataatcacgc
    30481 tataaaacaa tatgcatttt ttgcagggat gttgtcgtcc ctgaaaaagc aaaaatggag
    30541 aaaaggaatg agtgaatcat tacatctgac ccgcaatgga tcaattctgg aaattaccct
    30601 tgatcgtcca aaagcgaatg ctattgatgc aaaaaccagc tttgaaatgg gcgaagtatt
    30661 tctaaatttc cgtgacgatc cgcaattacg tgtcgccatt attaccggtg ccggagagaa
    30721 gttcttttcc gcgggctggg atttaaaagc ggcagcagaa ggcgaagcac cggatgctga
    30781 ctttggcccg ggtggatttg cgggattaac cgaaattttc aatctcgaca aaccggttat
    30841 cgcagctgtg aacggctatg cctttggcgg cggctttgaa ctggcgctgg cggcagattt
    30901 tattgtttgt gccgataatg ccagcttcgc cctgccggaa gccaaactgg gcatcgttcc
    30961 tgacagcggc ggcgtgctgc gtctgccgaa gatcctgccg cctgccatcg tcaatgaaat
    31021 ggtgatgacc ggcagacgaa tgggcacaga agaggcgctg cgttggggga tagtcaaccg
    31081 cgtggttagc caggcggaac tgatggataa cgcccgcgaa ctggcgcagc agctggttaa
    31141 cagcgccccg ctggcgattg cggcgctgaa agagatctac cgcaccacca gcgaaatgcc
    31201 ggtagaagaa gcgtatcgct atattcgcag cggcgtgttg aaacactatc cgtcggttct
    31261 gcattcggaa gatgccgttg aagggccgct ggcgtttgcc gagaagcgcg atccggtatg
    31321 gaaaggacgt taacaaccgt gagctattac gcctttgagg ggttaattcc ggtggttcac
    31381 ccgacggcgt ttgtccatcc cagtgccgtc ttgattggcg atgtgattgt gggagccggt
    31441 gtctacatcg gcccactcgc ctcactgcgt ggtgactacg ggcggttgat cgtgcaagcg
    31501 ggagccaata ttcaggatgg ctgcattatg catggctact gcgacactga caccatcgtt
    31561 ggggaaaacg gccatatcgg gcacggagcg atcctgcatg gttgtgtgat tggtcgcgat
    31621 gcattggtcg ggatgaacag cgtgattatg gatggcgcgg tcattggcga agagagcatt
    31681 gttgccgcca tgagctttgt caaagcaggc tttcacggcg agaaacgcca gttgttgatg
    31741 ggtacgccag cccgcgctgt acgcagtgtt agtgacgacg agttacactg gaaacggttg
    31801 aataccaaag agtatcagga tcttgtcggg cgctgtcatg catcgttaca tgaaacacag
    31861 ccactgaggc aaatggagga aaatcgcccc cgtttgcagg ggacgacgga tgtgacgcct
    31921 aaacggtgat cttgccggat gcgacctggt tgctggataa gatgctacaa catcgcatct
    31981 ggcaagcagg acgcccggta tcaacgagat aaaattaacg acgcatactc tttgacaaca
    32041 tcatctgcca cttctgctcg cggttaagtt ccgtgagcgg aacggcagga atacgcggcg
    32101 tctttcttac gccgactaat ttatcccggc tgttattgcg caggcgcgcg taaatttgct
    32161 catcgatatc gaccactttt accagtcgct ggcactggca tccccgtcct tccagcttat
    32221 tagggatcat cttaacttcg cagcttattt ctgcgacttc cgacagaata taagtcaggg
    32281 tattaaccgc cttgctgtgt tcaatatcga aatgaataga gatctctctt gctatcaccc
    32341 accgattttc agccatcatc cattcggcga ttaacaagta gagtggtttt tcaacatatc
    32401 cttcacacat acgaactcca gtttcacaaa ttaaaagtct ggctatgact cgttttgaag
    32461 caattaaaca aggccatatt aaaattgtgg atatatcgat agtatgcaac ttcaccgtcg
    32521 ataagtgtga gctaaatcct gcttatgtca tcaaaaatat cgattcccca aaagatttac
    32581 ttaatgggca aaaaaaacgg tcctcatcag agaaccgtat tacttattcg atcaaattag
    32641 cggatgaaaa atatccgcca tgacacgcta ttatttgatc tgcgcgtgca tttcctgcac
    32701 cgaaattact ttttcggtcg cgtcggcatt cagcgccatc gcggtagcga aaccaccgtt
    32761 cagggtggtg tcataatgca ctttatattg cagcgcactg cgacggatca cgcgggagtc
    32821 ttcaatcgcg cgacggcctg aagtggtgtt gatgatgtag gtatattcgc cattcttgat
    32881 gcggtcctga atgtgcggac ggccttcatg caccttgttc accagacgcg gattaatgcc
    32941 cgcttcgccc agcacaatcg ccgtgccgtg ggtcgcatcc agctcgaagc cctgtttcag
    33001 cagttttgcc gccaggtcca ccacgcgttc tttatcgcct tcgcgcacgg aaagcaacgc
    33061 acgaccgtgt ttcttcatgg tggagttgct gcccagctgc gctttggcaa acgcttcagc
    33121 gaaggtgcgg cccacgccca tcacttcccc agtggagcgc atttctggcc ctaacagcgg
    33181 gtcaacaccc gggaatttat tgaacggcag caccacttct ttcaccgagt agtacggcgg
    33241 gataacttct ttggttacgc cctgctcagc cagcgatttg ccagccatca cacgcgccgc
    33301 cacttttgcc agcggtacgc cggtggcttt ggagacgaac ggaacggtac gcgccgcacg
    33361 cgggttaact tcaatcaggt agacttcgtt gtttttcacc gcaaactgca cgttcatcag
    33421 accgcgcacc tgcaattcga aggccagttt ctgcacctgc tggcgcatca catcctgaat
    33481 ttcctgactt aaggtgtagg ctggcagaga acatgcggag tcaccggagt gcacgcccgc
    33541 ctgctcgatg tgctccatga tgccgccaat cagcaccatt tcgccgtcgc agatggcatc
    33601 cacgtcaact tctaccgcgt catcaaggaa gtgatccagc aacactggcg catcgttaga
    33661 cacgctgacc gccgtctgga agtagcgacg caggtcagct tcgtcataga cgatttccat
    33721 cgcccgaccg ccgagaacgt aagacggacg taccaccagc gggtagccaa tctctttcgc
    33781 cttctctacc gccatttcaa tagcggtaac ggtggcgttc gccggttgtt tcagtttcag
    33841 acgctcaacc gcatgctgga agcgttcacg gtcttctgca cggtcgatag catccgggct
    33901 ggtgccgata accggtacgc cagcagcttc cagcgcgcgc gccagtttca gcggggtctg
    33961 accgccgtac tgaacgataa cgcctttcgg cttctcaata cgcacgattt ctagcacatc
    34021 ttccagagtt accggctcga agtagaggcg atcggaagtg tcgtagtcgg tggagacggt
    34081 ttccgggtta cagttaacca taatggtttc gtaaccgtct tcgcgcagcg ccagcgaggc
    34141 gtgtacacag cagtagtcga attcgatacc ctgaccgata cggttcgggc cgccgccgag
    34201 aaccatgatt ttttcacggt cggtagacgg attcgcttcg cactcttctt cataagtgga
    34261 gtacatgtaa gcggtgtcgg tggcgaactc tgccgcacag gtatccacgc gcttataaac
    34321 cgggtgcagg tcatactggt cgcgcagctt gcggatttcc gcttcgcgca cgcccgccag
    34381 ttttgccaga cgcgcatcgg caaagccttt gcgtttcagc tggcgcagga attcagcgtt
    34441 caggccagtg atgcccactt ccgctacttt ctcttccaga cgcaccagtt cttcaatctg
    34501 taccaggaac cagcggtcaa tattggtcag gttgaacacg ccgtccacag acaggcccgc
    34561 acggaaggca tcggcgatgt accagatacg ctctgcgcca gcatctttca gttcgcgacg
    34621 gattttggtt aacgcttccg ggtcatcgag gctcactttc gggtcgaatc cagtcgcacc
    34681 gacttccagg ccgcgcagcg ctttttgcag ggattcctgc tgcgtgcgac caatcgccat
    34741 cacttcgcca accgatttca tctgagtggt cagacggtcg ttagcaccag cgaatttttc
    34801 gaagttgaag cgaggaattt tagtaaccac atagtcgatg gacggctcga aggaggccgg
    34861 agtacgtccg ccagtgatgt cgttcatcag ttcgtcgagg gtgtaaccca ccgccagttt
    34921 cgccgccact ttagcaatcg ggaaaccggt cgctttcgac gccagcgccg aagaacggga
    34981 cacgcgtggg ttcatttcga taacaatcag gcgaccgttt ttcgggttca ccgcaaactg
    35041 gacattggaa ccaccggttt caacgccgat ttcacgcagc accgccatcg aggcgttacg
    35101 catgatttga tattctttgt cggtcagcgt ttgggctggc gcgacagtga tggagtcacc
    35161 ggtatggatg cccatcgcat caaagttttc gatagagcag acgatgatgc agttgtcgtt
    35221 tttatcacgc accacttcca tctcgtactc tttccagccg atcagcgact catcaatcag
    35281 cagctctttg gttggggaga gatccagacc gcgggcgcaa atttcttcaa actcttcgcg
    35341 gttataagcg ataccgccgc cgctaccgcc catggtaaag gatgggcgaa taatgcacgg
    35401 gaagcccacg tcagcggcaa ccgccagcgc ttcttccatc gtgtgtgcga taccggaacg
    35461 cgcggtttcc agaccaattt tcttcatcgc tacgtcgaaa cgacggcggt cttctgcttt
    35521 atcaatcgca tcggcggtcg caccaatcat agtcacgccg aactcttcca acacgccctg
    35581 acgctccagc tccagcgcgc agttcagcgc cgtctgaccg cccatcgttg gcagcaccgc
    35641 gtccgggcgc tctttttcaa taatcttgcg tactacttcc cagtgaatcg gctcgatgta
    35701 ggtcgcatcg gccatttccg ggtcggtcat gatggtcgcc gggttggagt tcaccagaat
    35761 gacgcggtaa ccctcttcgc gcagggcttt acatgcttgc gcgccagagt agtcaaactc
    35821 acacgcctga ccgataacaa tcgggcccgc acccagaatc aggatacttt ttatatctgt
    35881 acgttttggc atggctcttt tactcctgat tacttagcgg ttttacggta ctgctcaatt
    35941 aactcgataa agtggtcgaa caacggcgct gcgtcgtgtg gcccagggct ggcttccggg
    36001 tgaccctgga agctgaacgc cggtttatca gtgcgatgaa tgccctgtaa cgtaccgtcg
    36061 aacagggatt tatgcgtgac acgcaggttt gcaggtaatg ttgcttcatc caccgcaaaa
    36121 ccgtggttct gggcggtgat catcaccacg tttttctcca catctttaac cggatggttg
    36181 ccgccgtggt gaccaaattt cattttgaca gtcttcgcac cgctcgccag cgccagcagc
    36241 tgatgaccga ggcagatgcc gaataccgga atatcggttt cgaggaattt ctggatggcg
    36301 gtaatggcgt aatcgcacgg ggccgggtcg ccaggaccgt tggagaggaa gatgccgtct
    36361 ggattcattt tcagcacatc ttccgcagaa gtttgcgccg gaacgatggt caggcgacag
    36421 cctctatcca ccagcatccg caggatgttg cgcttggcac caaaatcata agccacgacg
    36481 tggaacggca gctcgtcttc ttttttcgct tctggcaggc cgccggtcaa cgtccagctc
    36541 ccttgtgtcc agctataggc ttctgcggtg gtcacttctt ttgccagatc catgccattc
    36601 agacctggga acgcgcgggc tttttctaac gccaacgccg catccgggtt atcgcctgcg
    36661 ataatgcagc cattctgtgc gcctttctcg cgcagtaaac gcgtcagctt acgggtatcg
    36721 atatcggcaa tcgccacgat gttatgccgc ttcaggtaag aagagaggtc ttcggtatta
    36781 cggaagttgc tggcaatcag cggcaggtcg cgaatcacca gaccttgtgc atgtacctga
    36841 gaagattctt catcggcgtc attagtgccg acattgccaa tatggggata agtaagagta
    36901 acgatttgac gagaatagga aggatcagtg aggatttctt gataaccggt cattgaagta
    36961 ttgaaaacga cttccccaac cgccgaacct gttgccccta tggcccgacc gtgaaactgg
    37021 gttccgtctt ccagaaccaa tagcgctgac ttaatcaaaa caccctccag agaatattca
    37081 ctcactttat ttgcatatta attcacaatg atgacgtaaa tcaatgcaaa tctgcttacc
    37141 gacgaatttc tggcaaacgg cggcattctg gagatatggg cgctaaaagt caacttaatg
    37201 gcgggatttt ttatattatt ttgtggctca tgcatgtttt acaggcatta agcggcaaaa
    37261 agatcatata acctgttcta gaaaacgctt gcgcagcaag aagattgcat gaaataaaag
    37321 cgagtaggga aaagtggacc aaatggtcaa aatttacatt aaaacaacaa aaaccgaag
//
LOCUS       DADXDL010000044        37064 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.044, whole genome shotgun sequence.
ACCESSION   DADXDL010000044 DADXDL010000000
VERSION     DADXDL010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37064)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37064)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37064
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.044"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(27..308)
                     /locus_tag="IRB70_002504"
     CDS             complement(27..308)
                     /locus_tag="IRB70_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehE family protein"
                     /protein_id="HBC0632407.1"
                     /translation="MNKYWLSGIIFLAYGMASPAFSSQTATLTINGRISPPTCSMAMV
                     NGQPQQHCGQLTYDVDTRHQVSSPVKGVTTEVVVAGSDSKRRIVLNRYD"
     gene            complement(571..1680)
                     /gene="apbC"
                     /locus_tag="IRB70_002505"
     CDS             complement(571..1680)
                     /gene="apbC"
                     /locus_tag="IRB70_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310946.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster carrier protein ApbC"
                     /protein_id="HBC0632408.1"
                     /translation="MNEQSQAKSPEALRAMVAGTLANFQHPTLKHNLTTLKALHHVAW
                     MDDTLHVELVMPFVWHSAFEELKEQCSAELLRITGAKAIDWKLSHNIATLKRVKNQPG
                     INGVKNIIAVSSGKGGVGKSSTAVNLALALAAEGAKVGILDADIYGPSIPTMLGAENQ
                     RPTSPDGTHMAPIMSHGLATNSIGYLVTDDNAMVWRGPMASKALMQMLQETLWPDLDY
                     LVLDMPPGTGDIQLTLAQNIPVTGAVVVTTPQDIALIDAKKGIVMFEKVEVPVLGIVE
                     NMSVHICSNCGHHEPIFGTGGAEKLAEKYHTQLLGQMPLHISLREDLDKGTPTVISRP
                     ESEFTAIYRQLADRVAAQLYWQGEVIPGEISFRAV"
     gene            1812..3845
                     /gene="metG"
                     /locus_tag="IRB70_002506"
     CDS             1812..3845
                     /gene="metG"
                     /locus_tag="IRB70_002506"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBC0632409.1"
                     /translation="MTQVAKKILVTCALPYANGSIHLGHMLEHIQADVWVRYQRMRGH
                     EVNFICADDAHGTPIMLKAQQLGITPEQMIGEMSQEHQTDFAGFNISYDNYHSTHSEE
                     NRQLSELIYSRLKENGFIKNRTISQLYDPEKGMFLPDRFVKGTCPKCKSPDQYGDNCE
                     VCGATYSPTELIEPKSVVSGATPVMRDSEHFFFDLPSFSEMLQAWTRSGALQEQVANK
                     MQEWFESGLQQWDISRDAPYFGFEIPNAPGKYFYVWLDAPIGYMGSFKNLCDKRGDSV
                     SFDEYWKKDSTAELYHFIGKDIVYFHSLFWPAMLEGSNFRKPTNLFVHGYVTVNGAKM
                     SKSRGTFIKASTWLNHFDADSLRYYYTAKLSSRIDDIDLNLEDFVQRVNADIVNKVVN
                     LASRNAGFINKRFDGVLASELADPQLYKTFTDAAEVIGEAWESREFGKAVREIMALAD
                     LANRYVDEQAPWVVAKQEGRDADLQAICSMGINLFRVLMTYLKPVLPKLTERAEAFLN
                     TELTWDGIQQPLLGHKVNPFKALYNRIDMKQVEALVEASKEEVKAAAAPITGPLADDP
                     IQETITFDDFAKVDLRVALIENAEFVEGSDKLLRLTLDLGGEKRNVFSGIRSAYPDPQ
                     ALIGRHTIMVANLAPRKMRFGISEGMVMAAGPGGKDIFLLSPDAGAKPGHQVK"
     gene            3986..7774
                     /locus_tag="IRB70_002507"
     CDS             3986..7774
                     /locus_tag="IRB70_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WGR and DUF4132 domain-containing protein"
                     /protein_id="HBC0632410.1"
                     /translation="MKHFIYQDEKSHKFWAVEQQGNELHICWGKVGTKGQNQVKSFAD
                     AAAAEKAELKLIAEKVKKGYVEQAKDNSLQPSQTVTDSLKVADLSTIIQEQPSFVAET
                     RAADKNTDVILPWLAKDIAVVFPLEVVPTTLSHRRFPGDPVTPVDKLTQLRRLACGVS
                     QRDNKTATFDFSACTLEWQNFIAQAIDLINSPKTTKLPSPVMAVLAALELHCTRYKER
                     EDVMDQIIQEGGLEYATDVIIHLQQISIEWDYVNNNIVFLSSGISPDYLQQYSSFELR
                     LRKHLSLAEESLWQKCAQKLIAAVPHIPEWRQPLIALLLPEKPEIAHEIAQRLLGQKK
                     LPSLEWLKIVATDEHILASLEKYHEPYAIFDDYYCGAIWSATVLQEQGVAALPRFAPY
                     VASDYCADVLSHINHPFALTLLIRVAGHTKRCHDRMTKACAAFPHAALAALAELLVQK
                     EENSWRIMLMTMLISQPTLAEQVIPWLSTPAVAVLKSCQQQLKQPSNHASADLLPAIV
                     VSPPWLSKKKKSPIPVLDLAPLNLESICTITDTEAKEFQTHWDWEPHKPGEGAKDFLY
                     SLGYRRWDFDTYKYIGASDSAIDAWEREDFATLIQMFKAHHAPYQGEWHLNSLPFLPM
                     QKAIKLWEFLSKEPHTAVKPVMLYLRLAGMSGFLHSFSRYPQEGFAVANYFAATELAP
                     AVARAFNKLKTLRQDARTWLLKYPEHAITGLLPAALGKAGESQDNARAALRMLIENGY
                     PSLLQEIAQRYNQPEVTDAVNALLALDPLDNHPTKIPTLPAFYQPSLWTRPVLKANAQ
                     SLPDSALFHLGEMLRFPQEDTLYPGLLQVKDACTADSLAEFAWDLFTAWQTAGVPSKE
                     SWAFTALGVLGNGDTARKLTPLIRAWPGESQHKRATVGLDILAAIGSDIALMQLNGIA
                     QKLKFKALQERAKEKIADIAESRELTVAELEDRLAPDLGLDDNGSLLLDFGPRQFTVS
                     FDETLKPFVRDASGSRLKDLPKPNKSDDETQANDAVNRYKLLKKDARTVAAQQVARLE
                     SAMCLRRHWSPENFQLFLVEHPLVRHLTRRLIWGVYSTENELLACFRVAEDNSYSTAD
                     DDLFTLPEGDISIGIPHVLEISPTDAAAFGQLFADYELLPPFRQLDRNSYALTEVERN
                     ASELTRWAGRKCPSGRVMGLSNKGWVRGEPQDGGWIGWMIKPLGRWSLIMEIDEGFAV
                     GMSPAELSAEQLLSKLWLWEGKAESYGWGSHSTQEAQFSALDDITASELINDIEALFE
                     "
     gene            7784..11428
                     /locus_tag="IRB70_002508"
     CDS             7784..11428
                     /locus_tag="IRB70_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4132 domain-containing protein"
                     /protein_id="HBC0632411.1"
                     /translation="MDKELPWLADNAQLELKYKKGKTPLSHRNWPGEPVPVITENLIQ
                     TLGDKLLHIAEKKKNIVWRYENFSLEWQSAITQAINLIGEHKPSIPARTMAALACIAQ
                     NDSQQLLDEIVQQEGLEYATEVVIARQFIVRCYESDPLVVTLQYQKEDYGYGYGYGYR
                     SETYNEFDLRLRKHLSLAEESCWQRCADKLIAALPGLPQVRRPFIALILPEKPEIANE
                     LVGLECPWTHFHSKEWLKVVATDHRAVGKLERYWSQDIFSDREASYMSHENHFGYAAC
                     AALLREQGIAAVPRLAMYAHKEDCGSLLVKINHPQVIRTLLLVADKNKPSLQRVAKYS
                     KNFPHATLAALAELLALKEPPARPGYPIIEDKKLPAQQKARDEYWRTLLQTLMASQPQ
                     LAEEVMPWLSTQAQAVLDSYLSAPPKTVIDSTDNIQMPEILVSPPWRSKKKMTVPRLD
                     LAPFELTPQVYWQPGERERLAATESARYFSTESLAERMEQKSGRVVLQELGFGDDVWL
                     FLNYILPGKLDAARNSLIVQWHYYPGRVEEIMNGWSSPEAQLAEQALRNGHVEVLINI
                     WENDSYSRYRREKSIWNLYLLAQLPREMALTFWLRINEKKHLSAGEDYFLSIFGLDAL
                     PGLLLAFSHRPKETFPLILNFGATELALPVARVWRRFAAQRDLARQWILHWSEHTATA
                     LIPLVFTKSSDNSEAALLALRLLYEQGHGELLQTVANRWQRTDVWPALEQLLKQSPIE
                     IYPTRIPKAPDFWQPAMWSRPRLITNNQPVTDDALEIIGEMLRFTQGGRFYCGLEQLK
                     TFCQPQTLAAFAWDLFTAWQQVGAPAKDNWAFLALSLFGDESTARDLTTQILAWPQEG
                     KSARAVSGLNILTLMNNDMALIQLHHISQRAKSRPLRDNAAEFLQVVAENRGLSQEEL
                     ADRLVPTLGLDDPQALIFDFGPRQFTVRFDENLNPVIFDQQNVRQKSIPRLRADDDQL
                     KAPEALARLKGLKKDATQVSKNLLPRLETALRTTRRWSLADFHSLFVNHPFTRLVTQR
                     LIWAVYPANEPRRLLNAFRVAAEGEFCNAQDEPIDLPADALIGIAHPLEMTAEMRSEF
                     AQLFADYEIMPPFRQLTRRTVLLTPDESASNSLNRWEGKSATVGQLMGMRYKGWESGY
                     ENAFVYDLGEYRLVLKFSSGFNHYNVDSKALMSFRSLHVYRDNKSVTFAELDVFDLSE
                     ALSAPDVIFH"
     gene            11489..11809
                     /locus_tag="IRB70_002509"
     CDS             11489..11809
                     /locus_tag="IRB70_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632412.1"
                     /translation="MIVQKELVTIYDYEAPVPEEPFSFRLEIHKCSELFTGSIYRLER
                     FRLHPTFHQRDREDIDPLINDALIYIRDEFIDERKLRGESPETVIAIFNRELQNIFNQ
                     EIEK"
     gene            12385..13473
                     /locus_tag="IRB70_002510"
     CDS             12385..13473
                     /locus_tag="IRB70_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBC0632413.1"
                     /translation="MSPQNNHLQRPPVAVLYADELAKLKQNDHAPCPPGWQLSLPAAR
                     AFILGDSAQNISRKVVISPSAVERMLVTLATGRGLMLVGEPGTAKSLLSELLATAISG
                     DAGLTIQGGASTTEDQIKYGWNYALLINHGPSTEALVPAPLYQGMRDGKIVRFEEITR
                     TPLEVQDCLLGMLSDRVMTVPELTGEASQLYAREGFNIIATANTRDRGVNEMSAALKR
                     RFDFETVFPIMDFAQELELVASASARLLAHSGIPHKVPDAVLELLVRTFRDLRANGEK
                     KTSMDTLTAIMSTAEAVNVAHAVGVRAWFLANRAGEPADLVDCIAGTIVKDNEEDRAR
                     LRRYFEQRVATHKEAHWQAYYQARHRLP"
     gene            13484..15763
                     /locus_tag="IRB70_002511"
     CDS             13484..15763
                     /locus_tag="IRB70_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632414.1"
                     /translation="MSEPLIVGIRHHSPACARLVKSLIESQRPRYVLIEGPADYNDRV
                     DELFLAHQLPVAIYSYCQYQDGAAPGRGAWTPFAEFSPEWQALQAARRIQAQTYFIDL
                     PCWAQSEEEDDSPDTHEESQTLLLHATRMDNSDTLWDHLFEDESQQTALPSALAHYFA
                     QLRGDSPGDALNRQREAFMARWIAWAMQQNNGDVLVVCGGWHAPALAKMWRECPQEIN
                     KPELPSLADAVTGCYLTPYSEKRLDVLSGYLSGMPAPVWQNWCWRWGLQQAGEQLLKT
                     VLTRLRQHHLPASTADMAAAHLHAMALAQLRGHTLPLRTDWLDAIAGSLIKEALNAPL
                     PWSYRGVIHPDTDPILLTLIDTLAGDGFGKLAPSTPQPPLPKDVTCELERTGISFPAE
                     LTLNRFTPDGLAQSQVLHRLVILEIPGVVRQQGSTLTLAGNGEERWKLTRPLSQHAAL
                     IEAACFGATLQEAARHKLEADMLDAGGIGSITTCLSQAALAGLASFSQQLLEQLTLLI
                     AQENQFAEMGQALEVLYALWRLDEISGMQGAQILQTTLCAAIDRTLWLCESNGRPDEK
                     EFHAHLHSWQALCHILRDLHSGVNLPGVSLSAAVALLERRSQAIHAPALDRGAALGAL
                     MRLEHPNASAEAALTMLAQLSPAQSGEALHGLLALARHQLACQPAFIAGFSSHLNQLS
                     DDDFINALPDLRAAMAWLPPRERGTLAHQVLEHYQLAQLPISALQMPLHCPPQAIAHH
                     QQLEQQALASLQHWGVFHV"
     gene            15756..16892
                     /locus_tag="IRB70_002512"
     CDS             15756..16892
                     /locus_tag="IRB70_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBC0632415.1"
                     /translation="MSELNDLLTTRELQRWRLILGEAAETTLCGLDDNARQIDHALEW
                     LYGRDPERLQRGERSGGLGGSNLTTPEWINSIHTLFPQQVIERLESDAVLRYGIEDVV
                     TNLDVLERMQPSESLLRAVLHTKHLMNPEVLAAARRIVRQVVEEIMARLAKEVRQAFS
                     GVRDRRRRSFIPLARNFDFKSTLRANLQHWHPQHGKLYIESPRFNSRIKRQSEQWQLV
                     LLVDQSGSMVDSVIHSAVMAACLWQLPGIRTHLVAFDTSVVDLTADVADPVELLMKVQ
                     LGGGTNIASAMEYGRQLIEQPAKSVIILVSDFYEGGSSSLLTHQVKKCVQSGIKVLGL
                     AALDSTATPCYDHDTAQALVNVGAQIAAMTPGELAAWLAENLQS"
     gene            16889..18889
                     /locus_tag="IRB70_002513"
     CDS             16889..18889
                     /locus_tag="IRB70_002513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SWIM zinc finger family protein"
                     /protein_id="HBC0632416.1"
                     /translation="MNSLRPELLELTPQALTALSNAGFVKRSLKELENGNVPEISHKN
                     GALIATFSDGVRTQLANGQALKEAQCSCGASGMCRHRVMLVLSYQRLCATTQPTEKEE
                     EWDPAIWLEELATLPDATRKRAQALVAKGITIELFCTPGEIPSARLPMSDVRFYSRSS
                     IRFARCDCIEGTLCEHVVLAVQAFVQAKAQQAEFNHLIWQMRSEHVTSSDDPFASEEG
                     NACRQYVQQLSQALWLSGISQPLIHYEAAFSRAQQAAERCNWRWVSESLRQLRASVDA
                     FHARASHYHAGECLRQLAALNSRLNCAQEMARRDSVGEVPPVPWRTVVGAGIAGEAKL
                     DHLRLVSLGMRCWQDIEQYGLRIWFTDPDTGSILHLSRSWPRSEQENSPAATRRLFSF
                     LAGALAGGQIVSQAAKRSADGELLLATRNRLSSVVPLSPDAWQMLSAPLRQPGIVALR
                     EYLRQRPPACIRPLNQVDNLFILPVAECISLGWDSSRQTLDAQVISGEGEDNVLTLSL
                     PASACSPFAVERMAALLQQTDDPVSLVSGFVSFVEGQLTLEPRVMMTKNRAWALDAET
                     APVAPLPSASVLPVPSTAHQLLMRCQALLIQLLHNGWRYQEQSAIGQAELLANDLTAV
                     GFYRLAHVLAQFRNTESEARVEAMNNGVLICEQLFPMLQQQG"
     gene            19014..19475
                     /locus_tag="IRB70_002514"
     CDS             19014..19475
                     /locus_tag="IRB70_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416627.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YehR family lipoprotein"
                     /protein_id="HBC0632417.1"
                     /translation="MKAFNKLFSLVVASVLVFSLAGCGDKEESKKFSANLNGTEIAIT
                     YVYKGDKVLKQSSETKIQFASIGATTKEDAARTLEPLSAKYKNIAGVEEKLTYTDTYA
                     QENVTIDMEKVDFKALQGISGINVSAEDAKKGITMAQMELVMKAAGFKEVK"
     gene            complement(19516..19986)
                     /locus_tag="IRB70_002515"
     CDS             complement(19516..19986)
                     /locus_tag="IRB70_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBC0632418.1"
                     /translation="MLSNDILRSVRYILKANNNDLVRILALGNVEATAEQIAVWLRKE
                     DEEGFQRCPDIVLSSFLNGLIYEKRGKDESAPALEPERRINNNIVLKKLRIAFSLKTD
                     DILAILTEQQFRVSMPEITAMMRAPDHKNFRECGDQFLRYFLRGLAARQHVKKS"
     gene            complement(20033..20752)
                     /gene="yehT"
                     /locus_tag="IRB70_002516"
     CDS             complement(20033..20752)
                     /gene="yehT"
                     /locus_tag="IRB70_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310963.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BtsR"
                     /protein_id="HBC0632419.1"
                     /translation="MIKVLIVDDEPLARENLRVFLQEQSDIEIVGECSNAVEGIGAVH
                     KLRPDVLFLDIQMPRISGLEMVGMLDPEHRPYIVFLTAFDEYAIKAFEEHAFDYLLKP
                     IDEVRLEKTLARLRQERSKQDVSLLPENQQALKFIPCTGHSRIYLLQMKDVAFVSSRM
                     SGVYVTSHEGKEGFTELTLRTLESRTPLLRCHRQYLVNLAHLQEIRLEDNGQAELILR
                     NGLTVPVSRRYLKSLKEAIGL"
     gene            complement(20749..22434)
                     /gene="btsS"
                     /locus_tag="IRB70_002517"
     CDS             complement(20749..22434)
                     /gene="btsS"
                     /locus_tag="IRB70_002517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component regulatory system sensor histidine
                     kinase BtsS"
                     /protein_id="HBC0632420.1"
                     /translation="MYDFNLVLLLLQQMCVFLVIAWLMSKTPLFIPLMQVTVRLPHKF
                     LCYIVFSIFCIMGTWFGLHIDDSIANTRAIGAVMGGLLGGPVVGGLVGLTGGLHRYSM
                     GGMTALSCMISTIVEGLLGGLVHSILIRRGRTDKVFNPITAGAVTFVAEMVQMLIILA
                     IARPYEDAVRLVSNIAAPMMVTNTVGAALFMRILLDKRAMFEKYTSAFSATALKVAAS
                     TEGILRQGFNEENSMKVAQVLYQELDIGAVAITDREKLLAFTGIGDDHHLPGKPISST
                     YTLKAIETGEVVYADGNEVPYRCSLHPQCKLGSTLVIPLRGENQRVMGTIKLYEAKNR
                     LFSSINRTLGEGIAQLLSAQILAGQYERQKAMLTQSEIKLLHAQVNPHFLFNALNTIK
                     AVIRRDSEQASQLVQYLSTFFRKNLKRPSEFVTLADEIEHVNAYLQIEKARFQSRLQV
                     NIAIPQELSQQQLPAFTLQPIVENAIKHGTSQLLDTGRVAISARREGQHLMLEIEDNA
                     GLYQPVTNASGLGMNLVDKRLRERFGDDYGISVACEPDSYTRITLRLPWRDEA"
     gene            22656..23387
                     /gene="mlrA"
                     /locus_tag="IRB70_002518"
     CDS             22656..23387
                     /gene="mlrA"
                     /locus_tag="IRB70_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator MlrA"
                     /protein_id="HBC0632421.1"
                     /translation="MALYTIGEVALLCDINPVTLRAWQRRYGLLKPQRTDGGHRLFND
                     ADIDRIREIKRWIDNGVQVSKVKMLLSNENVDVQNGWRDQQETLLTYLQSGNLHSLRT
                     WIKERGQDYPAQTLTTHLFIPLRRRLQCQQPTLQALLAILDGVLINYIAICLASARKK
                     QGKDALVVGWNIHDTTRLWLEGWIASQQGWRIDVLAHSLNQLRPELFEGRTLLVWCGE
                     NRTSAQQQQLTSWQEQGHDIFPLGI"
     gene            23447..23554
                     /locus_tag="IRB70_002519"
     CDS             23447..23554
                     /locus_tag="IRB70_002519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohO"
                     /protein_id="HBC0632422.1"
                     /translation="MRIAKIGVIALFLFMALGGIGGVMLAGYTFILRAG"
     gene            complement(23535..24266)
                     /gene="yehW"
                     /locus_tag="IRB70_002520"
     CDS             complement(23535..24266)
                     /gene="yehW"
                     /locus_tag="IRB70_002520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehW"
                     /protein_id="HBC0632423.1"
                     /translation="MKMLRDPLFWLIALFVVLIFWLPYSQPLFAALFPQLPRPVYQQE
                     SFAALALAHFWLVGISSLFAVIIGTGAGIAVTRPWGAEFRPLVETIAAVGQTFPPVAV
                     LAIAVPVIGFGLQPAIIALILYGVLPVLQATLAGLGAIDASVTEVAKGMGMSRGQRLR
                     KVELPLAAPVILAGVRTSVIINIGTATIASTVGASTLGTPIIIGLSGFNTAYVIQGAL
                     LVALAAIIADRLFERLVQALSQHAK"
     gene            complement(24271..25197)
                     /gene="yehX"
                     /locus_tag="IRB70_002521"
     CDS             complement(24271..25197)
                     /gene="yehX"
                     /locus_tag="IRB70_002521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter ATP binding
                     protein YehX"
                     /protein_id="HBC0632424.1"
                     /translation="MIEFSHVSKLFGAQKAVNDLNLNFQEGSFSVLIGTSGSGKSTTL
                     KMINRLVEHDSGVIRFAGEEIRSLPVLELRRRMGYAIQSIGLFPHWSVAQNIATVPQL
                     QKWSRARIDDRIDELMALLGLESNLRERYPHQLSGGQQQRVGVARALAADPQVLLMDE
                     PFGALDPVTRGALQQEMTRIHRLLGRTIVLVTHDIDEALRLAEHLVLMDHGEVVQQGN
                     PLTMLTRPVNDFVRQFFGRSELGVRLLSLRSVADYVRREERAEGEALAEEMTLRDALS
                     LFVARGCEVLPVVNTQGQPCGTLHFQDLLEEA"
     gene            complement(25190..26347)
                     /gene="yehY"
                     /locus_tag="IRB70_002522"
     CDS             complement(25190..26347)
                     /gene="yehY"
                     /locus_tag="IRB70_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter permease YehY"
                     /protein_id="HBC0632425.1"
                     /translation="MTYLRINPVLALLLLLTAIAAALPFISYAPNRLVSGEGRHLWQL
                     WPQTIWMLVGVCCAWLTACFIPAKKGSIFALILAQLVFVLLVWGAGKAATQLAQNGSA
                     LARTSLGSGFWLAAALALLACSDAIRRISTHPLWRWLLHMQIAIIPLWLLYSGALNDL
                     SLMKEYANRQDVFDDALAQHLTLLFGAVLPALVIGVPLGVWCYFSTARQGAIFSLLNV
                     IQTVPSVALFGLLIAPLAALVTAFPWLGKLGIAGTGMTPALIALVLYALLPLVRGVVV
                     GLNQIPRDVLESARAMGMSGAQRFLHVQLPLALPVFLRSLRVVMVQTVGMAVIAALIG
                     AGGFGALVFQGLLSSAIDLVLLGVIPVIVLAVLTDALFDLLIALLKVKRND"
     gene            complement(26354..27271)
                     /gene="osmF"
                     /locus_tag="IRB70_002523"
     CDS             complement(26354..27271)
                     /gene="osmF"
                     /locus_tag="IRB70_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine ABC transporter
                     substrate-binding protein OsmF"
                     /protein_id="HBC0632426.1"
                     /translation="MPLSKVWAGSLVLLAAVSLPLQAASPVKVGSKIDTEGALLGNII
                     LQVLESHGVPTVNKVQLGTTPVVRGAITSGELDIYPEYTGNGAFFFKDENDTAWKNAQ
                     QGYEKVKKLDAEQNKLIWLTPAPANNTWTIAVRQDVVEKNKLTSLADLSRYLKEGGTF
                     KLAASAEFIERADALPAFEKAYDFKLDQDQLLSLAGGDTAVTIKAAAQQTSGVNAAMA
                     YGTDGPVAALGLQTLSDPQGVQPIYAPAPVVRESVLKEYPQMAQWLQPVFASLDEKTL
                     QQLNASIAVEGLDAKKVAADYLKQKGWTK"
     gene            complement(27544..29841)
                     /gene="bglX"
                     /locus_tag="IRB70_002524"
     CDS             complement(27544..29841)
                     /gene="bglX"
                     /locus_tag="IRB70_002524"
                     /EC_number="3.2.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucosidase BglX"
                     /protein_id="HBC0632427.1"
                     /translation="MKWLCSVGIAVSLALQPALADDLFGNHPLTPEARDAFVTELLKK
                     MTVDEKIGQLRLISVGPDNPKEAIREMIKDGQVGAIFNTVTRQDIRAMQDQVMELSRL
                     KIPLFFAYDVLHGQRTVFPISLGLASSFNLDAVKTVGRVSAYEAADDGLNMTWAPMVD
                     VSRDPRWGRASEGFGEDTYLTSIMGKTMVQAMQGKSPADRYSVMTSVKHFAAYGAVEG
                     GKEYNTVDMSPQRLFNDYMPPYKAGLDAGSGAVMVALNSLNGTPATSDSWLLKDVLRD
                     QWGFKGITVSDHGAIKELIKHGTAADPEDAVRVALKSGINMSMSDEYYSKYLPGLIKS
                     GKVTMEELDDAARHVLNVKYDMGLFNDPYSHLGPKESAPVDTNAESRLHRKEAREVAR
                     ESLVLLKNRLETLPLKKSATIAVVGPLADSKRDVMGSWSAAGVADQSVTVLTGIKNAV
                     GENGKVLYAKGANVTSDKGIIDFLNQYEEAVKVDPRSPQEMIDEAVQTAKQSDVVVAV
                     VGEAQGMAHEASSRTDITIPQSQRDLIAALKATGKPLVLVLMNGRPLALVKEDQQADA
                     ILETWFAGTEGGNAIADVLFGDYNPSGKLPMSFPRSVGQIPVYYSHLNTGRPYNADKP
                     NKYTSRYFDEANGALYPFGYGLSYTTFTVSDVKLSAPTMKRDGKVTASVQVTNTGKRE
                     GATVVQMYLQDVTASMSRPVKQLKGFEKITLKPGETQTVSFPIDIEALKFWNQQMKYD
                     AEPGKFNVFIGTDSARVKKGEFELL"
     gene            30037..31752
                     /gene="dld"
                     /locus_tag="IRB70_002525"
     CDS             30037..31752
                     /gene="dld"
                     /locus_tag="IRB70_002525"
                     /EC_number="1.1.1.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-lactate dehydrogenase"
                     /protein_id="HBC0632428.1"
                     /translation="MSSMTTTDNKAFLNELARLVGHSHLLTDPAKTARYRKGFRSGQG
                     DALAVVFPGSLLELWRVLKACVTADKIILMQAANTGLTEGSTPNGNDYDRDIVIISTL
                     RLDKLHVLGKGEQVLAYPGTTLYSLEKALKPLGREPHSVIGSSCIGASVIGGICNNSG
                     GSLVQRGPAYTEMSLFARINEDGKLTLVNHLGIDLGETPEQILSKLDDDRIKDDDVRH
                     DGRHAHDYDYVHRVRDIEADTPARYNADPDRLFESSGCAGKLAVFAVRLDTFEAEKNQ
                     QVFYIGTNQPEVLTEIRRHILANFENLPVAGEYMHRDIYDIAEKYGKDTFLMIDKLGT
                     DKMPFFFNLKGRTDAMLEKVKFFRPHFTDRAMQKFGHLFPSHLPPRMKNWRDKYEHHL
                     LLKMAGDGVGEAKSWLVDYFKQAEGDFFVCTPEEGSKAFLHRFAAAGAAIRYQAVHSD
                     EVEDILALDIALRRNDTEWYEHLPPEIDNQLVHKLYYGHFMCYVFHQDYIVKKGVDVH
                     ALKEQMLELLQQRGAQYPAEHNVGHLYKAPETLQKFYRENDPTNSMNPGIGKTSKRKN
                     WQEVE"
     gene            complement(31791..32723)
                     /gene="pbpG"
                     /locus_tag="IRB70_002526"
     CDS             complement(31791..32723)
                     /gene="pbpG"
                     /locus_tag="IRB70_002526"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311048.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine endopeptidase"
                     /protein_id="HBC0632429.1"
                     /translation="MPKFRVSLFSLALMLAVPLAPQAVAKTAAATTASQPEIASGSAM
                     IVDLNTNKVIYSNHPDLVRPIASISKLMTAMVVLDARLPLDEKLKVDISQTPEMKGVY
                     SRVRLNSEISRKDMLLLALMSSENRAAASLAHHYPGGYKAFIKAMNAKAKSLGMNNTR
                     FVEPTGLSVHNVSTARDLTKLLIASKQYPLIGQLSTTREDMATFSNPTYTLPFRNTNH
                     LVYRDNWNIQLTKTGFTNAAGHCLVMRTVINNKPVALVVMDAFGKYTHFADASRLRTW
                     IETGKVMPVPAAALSYKKQKAAQMAAAGQTAQND"
     gene            complement(32897..33484)
                     /locus_tag="IRB70_002527"
     CDS             complement(32897..33484)
                     /locus_tag="IRB70_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014170891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YIP1 family protein"
                     /protein_id="HBC0632430.1"
                     /translation="MSHVWGLFSHPDREMQVINRENETISHHYTHHVLLMAAIPVICA
                     FIGTTQIGWNFGDGTILKLSWFTGLALAVLFYGVMLAGVAVMGRVIWWMARNYPQRPS
                     LAHCMVFAGYVATPLFLSGLVALYPLVWLCALVGTVALFYTGYLLYLGIPSFLNINKE
                     EGLSFSSSTLAIGVLVLEVLLALTVILWGYGYRLF"
     gene            33654..34232
                     /locus_tag="IRB70_002528"
     CDS             33654..34232
                     /locus_tag="IRB70_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416640.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBC0632431.1"
                     /translation="MDLNTLISQYGYAALVIGSLAEGETVTLLGGVAAHQGLLKFPLV
                     VLSVALGGMIGDQVLYLCGRRFGGKLLRRFSKHQDKIERAQKLIQRHPYLFVIGTRFM
                     YGFRVIGPTLIGASQLPPKIFLPLNILGAFAWALIFTTIGYAGGQVIAPWLHNLDQHL
                     KHWVWLILVVVLVVGVRWWLKRRGKKKPDHQA"
     gene            complement(34351..35112)
                     /locus_tag="IRB70_002529"
     CDS             complement(34351..35112)
                     /locus_tag="IRB70_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBC0632432.1"
                     /translation="MAQVAIITASDSGIGKECALLLAQQGFDIGITWHSDEEGAKDTA
                     REVVSHGVRAEIVQLDLGNLPEGAQALEKLIHRLGRIDVLVNNAGAMTKAPFLDMAFD
                     EWRKIFTVDVDGAFLCSQIAARQMVKQGQGGRIINITSVHEHTPLPDASAYTAAKHAL
                     GGLTKAMALELVRHKILVNAVAPGAIATPMNGMDGGDVKPDAEPSIPLRRFGTTHEIA
                     SLVVWLCSEGANYTTGQSLIVDGGFMLANPQFNPE"
     gene            complement(35165..36601)
                     /gene="mdtQ"
                     /locus_tag="IRB70_002530"
     CDS             complement(35165..36601)
                     /gene="mdtQ"
                     /locus_tag="IRB70_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001583680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug resistance outer membrane protein
                     MdtQ"
                     /protein_id="HBC0632433.1"
                     /translation="MNRDSFYPAIACFPLLLMLAGCAPMHETRQALSQQTPAAQVDTA
                     LPTALKNGWPDSQWWLEYHDNQLTSLINNALQNAPDMQVAEQRIQLAEAQAKAVATQD
                     GPQLDFSADMERQKMSAEGLMGPFALNDPAAGTTGPWYTNGTFGLTAGWHLDIWGKNR
                     AEVTARLGTVKARVAEREQTRQLLAGSVARLYWEWQTQAALNTVLQQIEKEQNTIIAT
                     DRQLYQNGITSSVEGVETDINASKTRQQLNDVAGKMKIIEARLSALTNHQTKALKLNP
                     VALPKVASQLPDELGYSLLARRADLQAAHWYVESSLSTIDAAKAAFYPDINLMAFLQQ
                     DALHLSDLFRHSAQQMGVTAGLTLPIFDSGRLNANLDIAKAESNLSIASYNKAVVEAV
                     NDVARAASQVQTLAEKNQHQAQIEHDALRVVGLAQARFNAGIIAGSRVSEARIPALRE
                     RANGLLLQGQWLDASIQLTGALGGGYKR"
     gene            36825..36908
                     /gene="yohP"
                     /locus_tag="IRB70_002531"
     CDS             36825..36908
                     /gene="yohP"
                     /locus_tag="IRB70_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YohP"
                     /protein_id="HBC0632434.1"
                     /translation="MKIILWAVLIIFLIGLLVVTGVFKMIF"
BASE COUNT         9137 a         9883 c         9338 g         8706 t
ORIGIN      
        1 tccgattaaa aaaccagggt ggcaaattaa tcgtagcgat ttaacacgat tcgacgtttg
       61 ctatcgctac ctgcaacaac cacttctgtc gttacacctt tgactggcga agaaacctga
      121 tgacgggtat caacatcata cgttaactga ccacaatgct gttgaggttg tccattaacc
      181 atagccatac tgcatgttgg gggactgatc ctgccattaa tcgttaatgt ggcagtctgt
      241 gaagagaacg cgggagaagc cattccatag gcaagaaaaa taattcctga cagccagtac
      301 ttattcattg aacgttatcc ctgtagtaaa ggttatgcct ggatagaatg agtgcataac
      361 aaactatagc tgtacatcca ctacacagcc acgaaggatg ataatgaagc attgcctgta
      421 cgatcaatcg actttataga gtttcggacg aaggtccgca gaatatttgc agcattaaat
      481 aagtgttcat taatgcggca aaaacaaata caccgcatca atgtaacatc tctgcggtgt
      541 atgaaaagca accaaaaagg ttaatacgcg ttagaccgcg cggaaggaaa tctcgccagg
      601 aatgacttct ccctgccaat aaagctgggc tgcaacgcgg tcagccagct ggcggtagat
      661 agcggtaaat tcgctctccg gacggctgat aaccgttggc gtgcctttat cgagatcttc
      721 acgtaaggag atgtgtaacg gcatctgccc cagcaactgc gtgtggtatt tctcggccag
      781 tttctctgca ccaccggtac cgaaaatcgg ttcatggtga ccacagttac tgcaaatatg
      841 cacactcatg ttctcgacaa taccgagcac cggaacctcg actttctcga acatcacaat
      901 gccttttttc gcatcgatca acgcaatgtc ctgcggggtg gtgaccacta ccgcgccagt
      961 tactggaatg ttttgtgcca gtgtcaattg aatgtcacca gtgcctggcg gcatatcaag
     1021 caccagatag tcgagatccg gccacaaggt ttcctgcaac atttgcatta acgccttgct
     1081 cgccatcgga ccacgccaca ccatcgcatt gtcgtcagtg accagataac caattgaatt
     1141 ggttgcaagg ccatgagaca taatcggtgc catgtgggta ccgtccggcg aagttggacg
     1201 ctgattttct gcacccagca tggtgggtat tgatgggccg tagatatcgg cgtccagaat
     1261 gccgactttc gccccttccg ccgcgagtgc caacgccagg tttaccgccg tggaagattt
     1321 acccacgccg cctttaccgg aactgaccgc aatgatgttc ttcacgccat taatacccgg
     1381 ctgattcttc acgcgtttta aggtggcgat attgtgcgac agtttccagt cgatagcttt
     1441 cgccccggtg atacgaagca gttcggcgct acattgctct tttaactctt cgaacgcgct
     1501 atgccagacg aatggcataa ccagttccac atgcaacgtg tcgtccatcc aggcgacatg
     1561 gtgcaacgct ttcagcgtgg tgaggttatg cttcagggtt gggtgctgaa aattggccag
     1621 tgtcccggcg accattgcgc gcaaggcttc tggtgatttg gcctgggatt gttcgttcat
     1681 cccgactcct tttttgtata gataaaccat cagctgatag tttacctgaa gaatatagag
     1741 aagtacttac ttaacatttt cccatttggt actatctaac cccttttcac tattaagaag
     1801 taatgcctac tatgactcaa gtcgcgaaga aaattctggt gacgtgcgca ctgccgtacg
     1861 ctaacggctc aatccacctc ggccatatgc tggagcacat ccaggctgat gtctgggtcc
     1921 gttaccagcg aatgcgcggc cacgaggtca acttcatctg cgccgacgat gcccacggta
     1981 caccgatcat gctgaaagct cagcagctcg gtatcacccc ggagcagatg attggcgaaa
     2041 tgagtcagga gcatcagact gatttcgcag gctttaacat cagctatgac aactatcact
     2101 cgacgcacag tgaagagaac cgccagttgt cagaacttat ctactctcgc ctgaaagaaa
     2161 acggttttat taaaaaccgc actatttctc agctgtacga tccggaaaaa ggcatgttcc
     2221 tgccggaccg ttttgtgaaa ggcacctgcc cgaaatgtaa atccccggat caatacggcg
     2281 ataactgcga agtctgcggc gcgacctaca gcccgactga attgatcgag ccgaaatcgg
     2341 tggtttctgg cgctacgccg gtaatgcgtg attctgaaca cttcttcttt gatctgccct
     2401 ctttcagcga aatgttgcag gcatggaccc gcagcggtgc gttgcaggag caggtggcaa
     2461 ataaaatgca ggagtggttt gaatccggcc tgcaacagtg ggatatctcc cgcgacgcgc
     2521 cgtacttcgg ttttgaaatt ccgaacgcgc cgggtaaata tttctacgtc tggctggatg
     2581 cgccgattgg ctatatgggt tctttcaaga atctgtgcga caagcgcggc gacagcgtaa
     2641 gcttcgatga atactggaag aaagactcca ccgccgagct gtaccacttc atcggtaaag
     2701 atattgttta cttccacagc ctgttctggc cagcaatgct ggaaggcagc aacttccgca
     2761 agccgaccaa cctgtttgtt catggctatg tgacggtgaa cggcgcgaag atgtctaagt
     2821 ctcgcggtac ctttattaag gccagcacct ggctgaatca ttttgacgcc gacagcctgc
     2881 gttactacta cactgcgaaa ctctcttcgc gcattgatga tatcgatctc aacctggaag
     2941 atttcgttca gcgcgtgaat gccgatatcg ttaacaaagt ggttaacctg gcctctcgta
     3001 atgcgggctt tatcaacaag cgttttgacg gcgtgctggc aagcgaactg gctgacccgc
     3061 agttgtacaa aaccttcact gatgccgctg aagtgattgg tgaagcgtgg gaaagccgcg
     3121 aatttggtaa agcagtacgc gaaatcatgg cgctggctga tctggctaac cgctatgtcg
     3181 atgaacaggc tccgtgggtg gtggcaaaac aggaaggccg cgatgccgac ctgcaggcaa
     3241 tttgctcaat gggcataaac ctgttccgcg tgctgatgac ttacctgaag ccggtactgc
     3301 cgaaactgac cgagcgcgca gaagcattcc tcaatacaga actgacctgg gatggtatcc
     3361 agcaaccgct gctgggccac aaagtgaatc cgttcaaagc gctgtataac cgcatcgata
     3421 tgaagcaggt tgaagcactg gtggaagcgt ctaaagaaga agtgaaagca gctgccgcgc
     3481 caattactgg cccactggca gatgatccga ttcaggaaac catcaccttt gacgacttcg
     3541 ccaaagttga cctgcgcgtg gcgctgatcg aaaacgcaga gtttgttgaa ggttctgaca
     3601 aactgctgcg cctgacgctg gatctcggcg gtgaaaaacg caatgtcttc tccggcattc
     3661 gttctgctta cccggatccg caggcactga ttggtcgtca caccattatg gtggctaacc
     3721 tggcaccacg taaaatgcgc ttcggtatct ccgaaggcat ggtgatggct gccggtcctg
     3781 gcgggaaaga tatcttcctg ctaagcccgg atgctggtgc taaaccgggt catcaggtga
     3841 aataatcccc cttcaaggcg ctgcatcgac agcgcctttt ctttataaat tcctaaagtt
     3901 gttttcttgc gattttgtct ctctctaacc cgcataaata ctggtagcat cagcattcaa
     3961 ctggataaaa ttacagggat gcagaatgaa acactttatc tatcaggacg aaaaatcaca
     4021 taaattctgg gcggtggagc agcagggaaa cgagttgcat atctgttggg gaaaagttgg
     4081 caccaaaggg caaaaccagg taaaaagttt tgcggatgct gcggcggcgg aaaaagcgga
     4141 gctgaagctg attgcggaga aggtgaagaa gggatatgtg gagcaagcga aggataattc
     4201 tttgcaacct tcccaaacgg taacggactc tctcaaggta gcggacttat ccaccattat
     4261 tcaggaacaa ccctctttcg tagcagaaac ccgtgcggct gacaaaaata cagacgttat
     4321 tttaccgtgg ctggcaaaag atattgctgt cgtttttccg cttgaagtcg tacccaccac
     4381 cttaagccat cgccgctttc ccggagatcc tgttacacct gtagataaat taacccagtt
     4441 acgtcgctta gcctgtggcg tgtcgcaacg ggataacaaa acagctacat ttgacttcag
     4501 cgcctgtact ttagagtggc aaaacttcat cgctcaggcg atcgatctga ttaacagccc
     4561 gaaaacgaca aaattaccat caccggtaat ggctgtactc gcggcacttg aactgcactg
     4621 tacgagatat aaagagcgtg aggatgttat ggatcagatt attcaggaag gcggtctgga
     4681 atatgctact gatgtaataa tacatcttca acaaatatct attgaatggg attatgtcaa
     4741 caataatatt gttttcctgt cgtctggcat ttcacctgat tacttgcagc aatattccag
     4801 ctttgaatta cgcctacgta aacatttatc actggcggaa gagtctctct ggcaaaaatg
     4861 tgcacaaaaa cttattgccg cagttccaca tattccagaa tggcggcaac cattaattgc
     4921 tttgttatta cccgaaaaac cagaaattgc acatgaaatt gcccagcgtc tactggggca
     4981 aaagaaatta ccctcgcttg agtggctaaa aatagtggcg actgatgagc acattcttgc
     5041 ctcattagaa aaatatcacg agccatatgc catttttgat gattactatt gtggtgcgat
     5101 atggtcagcc accgtattac aggagcaagg tgttgcagcc ctgccccgat ttgcacccta
     5161 tgtcgcaagt gactactgcg ccgatgtgtt gagtcatatc aatcatccgt tcgcattaac
     5221 actgcttata cgtgtagccg ggcatactaa acgctgtcac gatcgaatga cgaaagcctg
     5281 cgctgcgttc ccacacgcag cactggcagc actggcggaa cttctagtgc aaaaagaaga
     5341 gaatagttgg cgcattatgc taatgacgat gcttatctcg caacctacac tagcagaaca
     5401 ggtcattccc tggctttcga cacccgcagt tgcagtgctg aaatcatgcc agcaacaact
     5461 gaaacagccc tcaaaccatg ccagtgccga tctactgccg gccatagtag tctccccacc
     5521 atggctttcg aaaaagaaaa aatcgccgat tccggtgctt gatttagcac cgctcaacct
     5581 cgaatccata tgcacaataa ccgacacaga agctaaagag tttcaaactc attgggactg
     5641 ggaaccgcat aagccaggtg aaggtgctaa agatttcctt tactcgctgg ggtatcgccg
     5701 ctgggatttt gacacatata aatatatcgg cgcttctgac tcggcaattg acgcatggga
     5761 acgtgaggac ttcgctacac tcatccaaat gtttaaagcc caccatgcac cgtatcaggg
     5821 ggagtggcat ctcaactcac ttcccttttt acctatgcaa aaagcgatta aactatggga
     5881 atttctcagc aaagagccgc ataccgcggt aaaacctgtc atgctttatt tgcgactggc
     5941 aggtatgagt ggttttctac actcgttttc acgctaccct caagaaggtt ttgcggttgc
     6001 taattatttt gccgcaacgg aactggctcc tgccgtcgcc cgcgccttta acaaactcaa
     6061 aactctacga caagacgccc gcacctggct gctgaaatat ccggaacatg ccattaccgg
     6121 cctgttgcct gcggcactcg gcaaagccgg tgaatcccag gataacgccc gtgccgcttt
     6181 acgtatgttg attgaaaatg gttatccgtc attactgcaa gaaatcgccc agcgttataa
     6241 ccagccggaa gtaaccgatg cggtgaacgc tctacttgcg ctcgatccct tagataatca
     6301 cccgactaaa atcccgacac ttccggcctt ttatcagcca tcgctctgga cgcgcccggt
     6361 attaaaagca aacgcccaat cactgccaga tagcgccctc ttccacctcg gtgaaatgct
     6421 ccgcttccct caggaagata cgctgtatcc ggggttatta caggtgaaag acgcctgtac
     6481 tgccgactca ctggctgagt ttgcctggga tctgtttacc gcctggcaga ccgctggcgt
     6541 gccgtcgaaa gagagctggg cgttcactgc attaggtgtt cttggcaacg gtgacaccgc
     6601 ccgcaaactg acgccattaa tccgcgcctg gcctggcgaa tctcagcata aacgtgccac
     6661 cgttgggttg gatattctcg ctgctatcgg cagcgatatc gccctgatgc agcttaacgg
     6721 catcgcccag aaactgaaat tcaaagcctt acaggagcgg gcgaaagaaa aaattgccga
     6781 cattgccgaa agtcgcgaac tcacagtggc agaacttgaa gatcggttag caccggatct
     6841 cggtctggat gataacggtt cgctgctgct ggatttcggg ccacggcagt tcaccgtcag
     6901 ctttgatgaa accttaaaac cgtttgtgcg tgatgcttcc ggcagccgcc tgaaagactt
     6961 gcctaaaccg aacaaaagcg atgatgaaac ccaagcgaac gatgcagtta accgctacaa
     7021 actgttgaaa aaagatgcgc gtaccgttgc cgcccagcag gtagcaaggc tggaatccgc
     7081 catgtgccta cgccgccact ggtcgccgga aaacttccag ctattcctgg ttgagcatcc
     7141 gctggttcgc cacttaaccc gccgtctgat ttggggcgtt tatagcaccg aaaacgagct
     7201 actggcctgt ttccgggtgg cagaagataa cagctacagc accgctgacg atgatctttt
     7261 caccctgccg gaaggcgata tctctattgg tattcctcac gttctggaaa tatcaccgac
     7321 ggatgccgcc gcctttggtc agctttttgc cgactacgaa cttttaccgc cgttccgtca
     7381 gctcgaccgc aacagttatg ccctgactga agtcgaacgc aacgccagcg aactaacccg
     7441 ctgggcaggc agaaaatgcc cgagcggtcg ggttatgggg ctgtcgaata aaggctgggt
     7501 gcgtggtgaa ccgcaggacg gtggctggat cggctggatg atcaaacctc tgggccgctg
     7561 gtcattaatc atggaaatcg atgaaggatt tgcagttggt atgtcgccag ccgaactcag
     7621 tgccgagcaa ctcttaagca agctgtggct atgggaaggc aaagcagaaa gctatggctg
     7681 ggggagtcat tcaacacagg aagcgcagtt ctccgcactc gatgacatca ccgccagcga
     7741 gttgattaac gatattgaag ccctgtttga ataaggaaag aacatggaca aggaattacc
     7801 gtggctggcg gataacgccc aactggaact gaaatataaa aaaggcaaaa caccactcag
     7861 ccatcgcaat tggccgggcg aaccggtgcc tgttatcact gaaaacctca tccagacact
     7921 gggtgataaa ttgctacaca ttgctgagaa gaaaaaaaac attgtctggc gttatgaaaa
     7981 tttttcactg gaatggcagt ccgccatcac gcaggccatc aacttgatcg gcgagcacaa
     8041 accctcaatt ccggcccgga caatggcggc gctagcctgt atcgcgcaaa atgatagcca
     8101 acagttactc gacgaaatcg tccaacaaga gggactggaa tatgcgactg aagtggtgat
     8161 tgcacgccag tttattgtac ggtgttatga gagtgatcct ctggtagtaa cattgcagta
     8221 tcagaaggag gactatggct atggctatgg ctatggttat cgctcagaaa cctataacga
     8281 attcgatctc cgactgcgta agcatctctc tctggcagag gaaagctgct ggcagcgttg
     8341 cgccgacaaa ctcattgccg cactgccagg actaccccaa gttcgccgtc cttttattgc
     8401 actcatcctc ccggaaaaac cagaaatcgc caatgagttg gtaggccttg aatgcccgtg
     8461 gactcatttt cattctaagg agtggttaaa agttgttgct actgaccaca gggcagtggg
     8521 aaaactcgaa cgctactgga gccaggatat atttagcgat cgcgaagcca gctacatgtc
     8581 gcatgaaaac cacttcggct acgcggcctg cgccgccctt ttgcgcgaac aaggaattgc
     8641 agccgttcca cgcctcgcga tgtatgccca taaagaagat tgcggtagcc tgctggtaaa
     8701 aattaaccat ccgcaggtca tccgcaccct gctgttagtt gctgataaaa acaaacccag
     8761 cctgcaacgt gtggctaaat acagtaaaaa cttcccccat gcgacgcttg ccgcactggc
     8821 agagcttctg gcgttaaaag aaccgcctgc acgccctggt tatccaatca tcgaagacaa
     8881 aaagctgcct gcacagcaaa aagctcgaga tgaatactgg cgtacgctgt tacaaacgct
     8941 gatggcatcg cagccacaac tggcagaaga ggtgatgccg tggttaagta ctcaagccca
     9001 ggcagtgctg gatagttatt tatcggcacc gcccaaaacg gttattgata gcaccgataa
     9061 catccaaatg cctgaaatcc tcgtttcacc accgtggcgt agtaagaaaa aaatgacagt
     9121 tccacgtctt gatttggcac cgttcgaatt aacgccgcaa gtttactggc aaccaggcga
     9181 acgagagagg cttgccgcca ctgagtctgc ccgttatttc agcacggaat ctcttgcgga
     9241 acgcatggaa caaaaaagtg gacgagttgt attacaggag ctgggttttg gagatgatgt
     9301 atggctgttt ttgaattata tactccccgg aaaactggat gctgcacgca attcactcat
     9361 tgttcagtgg cattactacc cagggcgggt tgaagagatc atgaatggct ggagctcccc
     9421 ggaagctcaa ttagcagaac aggcgcttcg caacggtcac gtagaagtgt taattaacat
     9481 atgggaaaat gacagctact cacgctatcg tcgggaaaag agtatctgga acctgtattt
     9541 attggcgcag ttgccgcgtg agatggcttt gactttctgg ctacgtatca atgagaaaaa
     9601 gcatctgtct gcgggagagg actattttct cagtatcttc ggattggatg ctctaccagg
     9661 tctgctgttg gctttttcac atcgtccaaa agaaacattt ccattaattt taaatttcgg
     9721 cgcaacagaa ctggccctgc ccgttgcccg cgtctggcga cgtttcgcgg cgcagcgtga
     9781 tctggctcgc cagtggattt tacattggtc ggaacataca gctactgcac ttatccctct
     9841 tgtcttcacc aaatccagcg ataatagcga agctgcatta cttgccctgc gtttacttta
     9901 cgaacaggga catggcgagt tactgcaaac cgtggcaaac cgctggcagc gtacagatgt
     9961 atggcctgcc ctggagcaat tacttaaaca gagtccaata gagatttacc cgacacgcat
    10021 tccaaaagcc cctgatttct ggcagccggc aatgtggtcc agaccgagac ttatcacgaa
    10081 taatcaacct gttactgatg atgctctgga aattatcggc gaaatgctgc gctttaccca
    10141 gggcggacgt ttttattgtg ggctggaaca actgaaaacg ttctgccagc cacaaacgct
    10201 ggccgctttt gcctgggatc tctttaccgc gtggcaacaa gttggcgccc ccgcaaaaga
    10261 caactgggca tttctggcgt taagtctctt cggtgacgaa agcacggctc gggatctgac
    10321 aacacagatc ctcgcctggc cacaggaagg caaatctgcc cgtgccgtca gtggcctgaa
    10381 catacttacc ctgatgaata atgatatggc gctgatacag ctgcatcata tatcgcaacg
    10441 ggcgaaatcc cgtcccttac gtgataacgc ggcggaattt cttcaggtgg tcgcagaaaa
    10501 tcgtggacta agccaggaag agttagcgga cagattagtc ccaacactgg gcctggatga
    10561 tccgcaggcg ttgatatttg attttggtcc ccggcagttt accgttcgct tcgatgaaaa
    10621 cctcaacccg gttatctttg atcagcaaaa cgttcgccag aaaagcattc cccggttgcg
    10681 cgccgatgac gatcagctga aagcgcccga ggctctggcc cgacttaaag ggctaaaaaa
    10741 agatgccact caggtgagca aaaacctgct cccgcgtctt gaaacagccc tacgcaccac
    10801 ccgacgctgg tcgctggcag attttcattc tctgtttgtt aatcatccct ttacccgtct
    10861 ggttacccag cgattaatat gggcggttta tccagcaaat gaaccgcgtc gtttactcaa
    10921 cgcctttcgt gtggccgcag agggggaatt ctgcaacgca caagatgagc caattgacct
    10981 gcctgccgat gccctgattg gcattgccca cccgttagaa atgacagcag aaatgcgcag
    11041 tgaatttgca cagctttttg ccgattacga aattatgccg ccttttcgcc agttgacgcg
    11101 gcgcacagtg ctgctcacgc ctgacgagtc agccagtaat agtttgaatc gctgggaagg
    11161 taaatctgct accgttgggc aacttatggg aatgcgatac aaaggctggg agtcaggcta
    11221 tgagaacgca tttgtctatg acctgggcga gtaccggctg gtccttaagt tttcatccgg
    11281 ttttaaccac tacaatgttg atagcaaagc gctaatgagc ttccgttctc ttcatgtata
    11341 ccgtgacaat aaatctgtca cttttgccga acttgatgtg tttgatttga gtgaagcgtt
    11401 aagcgcaccc gacgtcattt tccattaaaa cacagcgggc agtgatgcga ctgcccgtta
    11461 ttaacacgac ctgccaccgg gggaagcgat gatcgtgcaa aaagagctgg tcactattta
    11521 cgattatgag gcccctgtac ctgaagagcc gttttccttc agacttgaga tccataaatg
    11581 ctctgaatta tttacaggtt ccatctaccg gctggagcga ttccggctac atccaacatt
    11641 tcatcaacgt gatcgagagg atatcgaccc gctaataaat gatgcgttga tttatataag
    11701 agatgagttt attgatgagc gaaaattacg gggcgaatca ccagaaacgg taatagccat
    11761 ttttaatcgt gaactacaga atatattcaa ccaagaaata gaaaaatagc tttattaaag
    11821 ggggaaacgg tattccccct tagatgcgtt tcaatttgcc cgttacttca acaaatcaat
    11881 caaccgtaac agagccacta atagctccag tacggcaatg agcacggtta acttttgtgt
    11941 cagcgtgtcc atccgctctc cttattaagg agcgcaacac cagcatctta cccttacact
    12001 gcctgtcgat actggtttac gtatgctgga ccacgatgtt gcactccgga tcagggcact
    12061 acctgcggca ccacccgtcc ggtagccagg acttgaaatg ggttcgatcc ggcgcaacgt
    12121 cccaacagtc aggattataa atctcattat cttaattgca acggggtcca ccgatggtta
    12181 taattcgttc gttggaacac gatgttgcac aggccgtggt gttaggcctg aaagtagtaa
    12241 ataaaagaac ctgcctcacc agcaggtttt tttatttact gtgatctgtt tcccagatat
    12301 tttccgctca aacaactaat gcgccaaaca tttattgcgc gtaaaatatc gtttatttca
    12361 ttaatacatt tcagggatga atatatgtca ccgcagaata atcatctgca gcgtccgcct
    12421 gtcgctgtgt tatacgccga tgaactggca aaattaaaac aaaatgatca cgcaccttgc
    12481 ccgcccggtt ggcagttaag tttgcctgcg gcccgtgctt ttatccttgg cgatagcgcg
    12541 caaaatatta gccgtaaagt ggtgattagt ccctccgctg tcgaacgcat gttagtcact
    12601 cttgccaccg ggcgcggttt gatgttggtg ggggaacctg gcaccgcaaa atctctcctg
    12661 tctgaattac tggcaaccgc tattagcggc gatgccgggt taaccatcca gggcggcgca
    12721 tctaccactg aagatcaaat caagtacggc tggaactacg ctctgcttat caaccatggt
    12781 ccgtcaacgg aagcactggt ccctgccccg ctttaccagg gaatgcgcga cggcaaaatc
    12841 gtccgttttg aagagataac gcgtacaccg ctggaagtac aagactgtct gttaggtatg
    12901 ctttctgaca gggtaatgac ggtgccggaa ctcactggtg aagccagtca gctctatgcg
    12961 cgagaaggct ttaatattat tgccactgcc aatacccgcg atcgcggcgt caatgaaatg
    13021 agcgctgcgc taaagcgtcg attcgatttt gaaacggtct ttccgattat ggatttcgcc
    13081 caggaactgg aactggtcgc cagtgcttcg gcgcgtttat tggcccatag tggcattccg
    13141 cataaagtgc ctgacgcggt actggagtta ctggtacgca ccttccgcga tctgcgtgcc
    13201 aacggcgaaa agaaaacgtc aatggataca ctgacagcga ttatgtccac cgctgaagcc
    13261 gtgaacgtag cccacgctgt gggtgtccgc gcctggtttt tagcgaatcg cgcaggtgag
    13321 ccagccgatc tggtggactg tattgccgga accatcgtta aagataacga agaagatcgc
    13381 gctcgtctgc gccgttactt cgaacagcgt gtcgccacac ataaagaagc tcactggcag
    13441 gcttattatc aagcccgcca ccgcctgccg tgaggaaaga tgcatgagcg agccgttaat
    13501 tgtcggcatc cggcatcata gcccggcctg cgcccggctg gtgaaatcgt taatcgaaag
    13561 ccagcggcca cgatacgtgt tgattgaagg cccggctgat tataatgacc gggtagacga
    13621 actgttttta gcccaccagc ttccggtagc tatttacagt tattgccagt atcaggacgg
    13681 tgcagccccc gggcgtggtg cctggacgcc atttgctgaa ttttcgccgg agtggcaggc
    13741 gctacaagcc gctcgtcgta ttcaggcaca aacttacttc atcgatttgc cttgctgggc
    13801 gcagagtgaa gaagaggacg attcgcctga tacgcatgag gaaagccaga ccttgctgct
    13861 gcatgccacc cgcatggata acagcgacac cctgtgggat cacttgttcg aagatgaaag
    13921 ccagcaaact gcattaccct ctgcactggc gcactatttt gcccaactgc ggggcgactc
    13981 ccccggagat gctctcaatc gtcagcgcga agcctttatg gcccgctgga ttgcatgggc
    14041 gatgcagcaa aataatggcg acgtgttagt tgtctgcggt ggctggcacg ctccggcact
    14101 ggcaaaaatg tggcgcgaat gcccgcaaga aattaacaag ccagaattgc cgtcgctggc
    14161 agatgccgtt acaggttgct atctcacgcc atacagtgaa aagcgccttg atgtgctgtc
    14221 aggatacctt tcaggaatgc ctgccccggt ctggcaaaac tggtgctggc ggtggggctt
    14281 gcagcaggca ggtgaacaac tactgaaaac ggttcttacc cgtttgcgcc agcaccactt
    14341 gcctgcttca acagcggata tggctgccgc tcatctgcat gcgatggcac tggcacagtt
    14401 gcgcggtcat acactaccgt tacgcactga ctggctggat gctatagccg gctcgctgat
    14461 caaagaagcc ctgaacgcgc cgttgccgtg gagctatcgc ggcgttattc atcccgatac
    14521 cgatccgatt ctgctaacgt tgatagacac attagcgggt gacggattcg gtaaacttgc
    14581 cccctcgacg ccacagccac ctctgccaaa agatgtcacc tgcgaactgg aacgtaccgg
    14641 aatctctttt ccggcggagc ttaccttaaa tcgctttacc cccgatggac tggcgcaaag
    14701 tcaggtgtta catcggctgg taatactgga gatcccaggg gttgtgcgcc agcagggaag
    14761 tacactgaca cttgcaggca acggtgaaga acgctggaaa ttaacccgcc cgcttagcca
    14821 acatgcggca ttaattgagg ccgcctgctt tggtgccaca ctccaggaag ccgcacgcca
    14881 taaattagaa gccgatatgc tggacgcggg tggaatcggc agtatcacca catgtcttag
    14941 ccaggcggcg ttagcgggtc tggcgtcctt cagtcaacaa ttactggagc aacttacatt
    15001 attaatcgcc caggaaaatc agtttgccga aatgggccag gcgctggaag tgctatacgc
    15061 cttatggcgg ctggatgaaa ttagcggtat gcaaggcgcg cagatattac agacgacgtt
    15121 atgcgcagct atcgatcgca cactctggct gtgtgaatcc aacggcagac cggatgaaaa
    15181 ggagtttcac gctcacctgc atagctggca agcgctttgc catatcctgc gcgatctaca
    15241 tagcggcgtt aatttacccg gcgtttcgct ttctgcggcg gtagccttac tggagcgccg
    15301 cagtcaggcg attcatgccc cggcgctgga tcgcggcgcg gctcttggcg cactaatgcg
    15361 tctggaacat cccaacgcca gtgccgaagc ggcgctgacg atgctggcgc agttatcccc
    15421 ggcacaatcc ggcgaggcgc tgcacggttt gctggcatta gcccgtcatc aactggcctg
    15481 tcagccggca tttatcgccg gtttcagtag tcatttaaat caactgagtg acgacgattt
    15541 tattaacgcc ctgcccgatt tacgcgcggc gatggcctgg ctaccaccac gagaacgcgg
    15601 gacgctggcg catcaggtgc ttgagcatta ccagctcgca cagcttccca tttcagcgct
    15661 gcaaatgccg ttgcattgtc caccgcaagc cattgcacat catcaacaac tcgaacagca
    15721 ggcactggca tcgctgcaac actggggagt tttccatgtc tgaactgaac gatcttctga
    15781 ccacccgtga gctacaacgc tggcgattaa ttcttggcga agcggcagaa acgacgcttt
    15841 gtgggctgga tgacaacgcc cggcagatag accacgcgct ggagtggctg tacgggcgcg
    15901 atcctgaacg gctccagcgt ggtgaacgct ccggtggatt aggtggctca aatctcacca
    15961 cccctgagtg gatcaacagt attcacacgc tgtttccgca acaggtgatt gaacggctgg
    16021 aaagcgatgc cgtactgcgc tacggcattg aagatgtggt gacaaatctc gacgtgctgg
    16081 aacgtatgca gccttcggaa agcctgctac gcgccgtttt gcacaccaaa catctgatga
    16141 atcccgaagt actggctgcc gcccgccgga tagtacgcca ggttgtggaa gaaattatgg
    16201 cgcgactggc aaaggaagtt cgtcaggctt tttctggtgt ccgcgatcgc cgtcgccgct
    16261 catttattcc actggcgcga aactttgatt tcaaaagtac tctgcgcgcc aacctgcaac
    16321 actggcaccc gcaacacggc aagttgtata tcgaatcccc ccgctttaac agccgcatta
    16381 aacgccaaag cgaacaatgg caactggtct tactggttga tcaaagcgga tcaatggtgg
    16441 actcggtgat ccactcagcg gtgatggcgg cctgtttatg gcagttaccc ggtattcgta
    16501 cccatctggt ggcgtttgac accagcgtgg ttgatctcac ggcagacgtt gccgatccgg
    16561 tagagttatt aatgaaagtg caattaggcg gcggaaccaa tatcgccagt gccatggaat
    16621 atggtcggca acttattgaa caaccagcga aaagcgtcat catcctcgtg agcgattttt
    16681 acgaaggggg ttcatcatca ttactgacgc atcaggtgaa aaagtgtgtc cagagcggca
    16741 tcaaagtgct gggactggcg gcgctcgata gcaccgcaac accttgctat gaccacgata
    16801 cggcccaggc gctagttaat gtcggcgcac aaatagccgc catgacaccg ggcgagctgg
    16861 cggcctggct tgcggagaat cttcagtcat gaattcacta cgtccggaat tattagaact
    16921 gacgccgcag gccctgacgg cgttaagcaa tgccggtttt gttaaacgca gtcttaagga
    16981 actggaaaat ggcaacgtcc cggaaatcag ccataagaac ggcgctttaa tcgccacctt
    17041 cagtgacggt gtccgtaccc agctggcgaa cggtcaggca ctgaaagagg ctcaatgcag
    17101 ctgcggggcc agcggcatgt gccgccatcg cgtgatgctg gttttaagtt atcagcgact
    17161 ttgcgccacc acccagccta cggaaaaaga agaagagtgg gatccggcaa tctggctaga
    17221 agaactggct acccttcccg atgccacccg caaacgcgcg caggcgctgg tcgctaaagg
    17281 catcaccatt gagttgttct gtacgccggg cgaaattccc tctgcccgct taccgatgag
    17341 cgatgtacgt ttttattccc gcagcagcat tcgtttcgca cgctgtgatt gtattgaagg
    17401 aacactttgc gaacatgttg tgctggcagt acaggccttt gtccaggcca aagcgcagca
    17461 agcagaattt aaccatttaa tctggcagat gcgcagcgaa cacgtcacat catctgacga
    17521 tccgtttgcc agcgaagagg gcaacgcgtg tcgtcaatat gttcagcaac taagccaggc
    17581 attatggctg agcggcatca gccagccgct tattcattac gaggccgctt tcagccgcgc
    17641 gcagcaagcg gcggaacgct gcaactggcg ctgggtaagt gaatcactac gacagctacg
    17701 ggcaagcgtt gatgccttcc acgcccgcgc cagtcactat catgccggag aatgcttacg
    17761 tcagcttgcg gcattaaaca gtcgattaaa ttgcgcacaa gagatggcgc ggcgcgacag
    17821 tgttggtgaa gttcctcctg tgccgtggcg cacggtcgtt ggcgctggca ttgccggaga
    17881 agcaaagctt gatcatctgc ggctggtgtc tttaggtatg cgttgctggc aggatattga
    17941 gcagtatggt ttacgcatct ggttcaccga tcccgacacc ggcagtattt tgcatctttc
    18001 gcgtagttgg ccgagaagcg aacaggaaaa ttcaccggca gcgacgcgtc ggctgtttag
    18061 ttttctggct ggcgcactgg caggtgggca aattgtttca caagcagcaa aacgcagtgc
    18121 cgatggcgaa ctgctattag ctacccgcaa ccgcttgagt agtgttgtgc cgctgtcgcc
    18181 agacgcctgg caaatgttga gcgcgccatt gcgccagccg ggcattgtgg ctttgcggga
    18241 atatttacgc cagcgtcccc ccgcctgcat acggcctctt aatcaggtgg ataacttatt
    18301 tattctgcca gtcgctgagt gtatttcact cggttgggat agcagccgcc agacactgga
    18361 tgcgcaggta atcagcggcg aaggtgaaga taacgtgctg acattatccc taccagcctc
    18421 tgcctgttcg ccctttgctg ttgaacgcat ggcggcgctt ttgcaacaaa cagacgaccc
    18481 cgtgagtctg gtttctggct ttgtcagctt tgtagagggg caattgacac tggaaccacg
    18541 ggtgatgatg acaaaaaacc gcgcctgggc gctggacgca gaaactgcgc ctgtggcacc
    18601 gctaccttct gccagcgttt tgcctgtgcc gtctaccgct catcagttgc tgatgcgctg
    18661 ccaggcgtta cttattcaac tgctccataa cggctggcgc tatcaggaac agagtgctat
    18721 tggtcaggca gagttgctgg cgaatgacct caccgcggtg ggtttttatc ggctggcaca
    18781 tgtgttggca caatttcgta atacagaaag cgaggcacgg gtagaagcaa tgaataacgg
    18841 tgttttgatt tgcgaacaat tattccccat gcttcagcaa caaggatgaa atagtgcttt
    18901 ttactaagag ttctactcca gttccggact gctcacgcca cagtattagg catatcctat
    18961 atagcccctg gtgagagtca ccagttcctt gattaaataa aatggagttt tacatgaagg
    19021 ctttcaataa gctgttttcc cttgttgttg catctgttct ggttttctct cttgctggct
    19081 gcggtgacaa agaagaatca aagaaattca gcgccaatct gaacggcact gaaattgcca
    19141 ttacctatgt ctacaaaggt gacaaggtgc ttaagcaatc ttctgaaacc aaaattcaat
    19201 ttgcctccat tggtgcaacc accaaagaag atgccgccag gacacttgag ccgttaagcg
    19261 ccaaatacaa aaacatcgcg ggtgttgaag aaaaattaac ctataccgat acctacgcgc
    19321 aggaaaacgt gactattgat atggaaaaag tggattttaa agccctgcag ggtatttcag
    19381 gaatcaacgt ttctgctgaa gatgccaaaa aaggtatcac tatggcgcaa atggaactgg
    19441 tgatgaaagc cgctggtttt aaagaagtga aataatctgt cggcggccat gtttcgcatg
    19501 gccgccatac ccgtcttagc ttttcttcac atgctggcgc gctgccagtc cacgcagaaa
    19561 ataacgtaaa aattgatcgc cgcattcgcg gaagttttta tgatccggtg cacgcatcat
    19621 cgccgtaatt tccggcatcg aaacgcggaa ctgctgttcg gtgaggattg ccagaatgtc
    19681 atcggtttta agcgaaaacg cgatgcgtaa ttttttcagc acgatgttgt tattaatgcg
    19741 acgttccggc tccagtgccg gagcagactc atccttgccg cgtttttcat aaatcaggcc
    19801 attgaggaat gacgacaaaa caatgtccgg acaacgctga aaaccctctt cgtcttcttt
    19861 acgtagccag acggcgatct gttccgcggt ggcttcgaca ttacccagcg ccagaatacg
    19921 caccaggtca ttattattgg ctttcaaaat gtagcgcacg ctgcgcagaa tatcgttact
    19981 tagcatgagg ccttcaggtg ttgatgaggc aaaaagccat tttagcagtc ttttacaggc
    20041 caatcgcctc ttttaagctt ttcagataac ggcggctgac cggcacggtt aagccattac
    20101 gcaaaatcaa ctcggcctgg ccgttatctt ccagacgaat ctcctgtaaa tgcgcgaggt
    20161 taaccagata ctgacgatgg cagcgcagta atggtgtacg actttccagg gtacgtaatg
    20221 tcagttcggt aaagccctct ttcccttcgt gactggtaac gtagacaccg ctcatccgac
    20281 tgctgacaaa tgccacatct ttcatttgca gcaaataaat ccgactatgc cccgtacaag
    20341 ggataaattt cagcgcctgt tgattttccg gtaacagcga aacatcctgc ttgctgcgct
    20401 cctgacgcaa tcgcgccagc gttttctcca gtcgcacttc atcaattggc ttcagcagat
    20461 aatcaaaggc atgttcttca aaggctttaa tggcgtattc gtcaaacgcg gtgagaaaaa
    20521 caatatacgg gcgatgttcc gggtcgagca tccccaccat ttccagacca ctgatgcgcg
    20581 gcatctggat atcgagaaac agcacatccg ggcgcagttt atgcaccgcg ccgatccctt
    20641 ctacggcgtt tgaacactct ccaacgattt caatatcgct ctgctcctgc aaaaatacgc
    20701 gcaggttctc ccgtgctaac ggttcatcat cgacaattaa gactttaatc atgcctcgtc
    20761 cctccatggt agtcgtaacg ttattcgggt gtaactatca ggctcacagg cgacgcttat
    20821 cccatagtca tcgccaaacc gttcacgtaa acgcttatcc accagattca tccccagccc
    20881 actggcattg gttaccggtt gatacaaacc ggcattgtct tcgatctcca gcatcaaatg
    20941 ttgcccctca cgtcgggcgc tgattgccac tcgccctgta tccagcagtt gtgatgtccc
    21001 atgtttaatg gcgttttcca ctatcggttg cagggtaaac gcgggcaatt gctgctggga
    21061 taattcttgc ggaatagcaa tgttgacctg caaccgcgac tggaagcgcg ccttttcaat
    21121 ttgcagataa gcgttcacat gttcaatttc gtcggcgaga gtaacaaact ccgaaggccg
    21181 ctttaagttt ttgcggaaaa aagtggaaag atactgcacc agctggctgg cctgttcgct
    21241 gtcgcggcgg atcaccgctt taatggtgtt aagcgcatta aacaaaaaat ggggattcac
    21301 ctgggcgtga agcagtttga tctctgactg ggtgagcatc gctttttgcc gctcatattg
    21361 cccggcgagg atctgcgccg aaagcagttg cgcaatcccc tcgcccagcg tgcggttgat
    21421 tgaactgaat aaacggtttt tggcttcata caatttgatg gtacccatca ctcgctgatt
    21481 ttcaccacgc aacggaatga ccagcgtcga ccccagtttg cattgcggat gcaaagagca
    21541 acggtaaggc acttcgttgc catcagcgta gaccacttca ccggtttcaa tcgcttttaa
    21601 ggtataagtt gaagaaatcg gtttgccggg taaatggtgg tcgtcaccaa ttccggtaaa
    21661 ggccagcaat ttctctcgat cggtaatcgc gactgcacca atatccagct cctgatacag
    21721 cacctgtgcc actttcatgc tgttctcttc gttaaacccc tggcgcaaaa tgccttccgt
    21781 cgaggccgcc actttcagcg cagtggcaga aaaagccgaa gtgtattttt caaacatcgc
    21841 gcgtttatcg agcaatatac gcataaacag tgccgcgccg acggtattgg tgaccatcat
    21901 tggcgcagca atattactca ccagacgcac cgcatcttca taaggtcggg cgatcgccag
    21961 gatgatcaac atttgcacca tttcagcgac gaacgtgacg gcaccggcgg taatggggtt
    22021 aaagacttta tcagtgcgcc cgcgacggat caggatgctg tgtaccaggc cgccgagcaa
    22081 tccttcaacg atggtcgaga tcatgcaact tagcgcggtc atgcccccca tcgaatatcg
    22141 atgtaacccg ccggtcagac caaccagccc accgacgacc ggaccgccga gtaagccgcc
    22201 cattaccgcg cctatcgcac gggtattggc aatagaatcg tcaatgtgca acccaaacca
    22261 ggtgcccatg atgcagaaga tggaaaagac gatgtagcag agaaatttat gcggcagacg
    22321 aaccgtgacc tgcattagcg gtatgaataa tggcgtttta ctcattaacc acgcaatgac
    22381 taaaaaaacg cacatctgct gaagcagcag caacaccaga ttaaaatcgt acatacccgc
    22441 aaaccacact tccctttaaa acgcgtaaca tacattgctt gcgtttaact ttctttgaac
    22501 tcttgcagaa aaatgagaat tcgtgagtac gatcactcaa aatcgcctgg caaaaataaa
    22561 atcaccctat agatgcacaa aaaacgggca aaactacctg gttcgcaaaa ctgcgtctaa
    22621 agttaaaccg ggacctcgcg agcaagggtg agacgatggc gctttacaca attggtgaag
    22681 tggcgttgct ttgtgatatt aaccctgtca cgttacgcgc gtggcagagg cgttacggat
    22741 tgctgaaacc gcaacggaca gacggcggtc atcggctgtt caatgatgcc gatattgacc
    22801 gtatccgcga gatcaaacgc tggatcgaca acggcgtgca ggtcagcaaa gttaaaatgc
    22861 tgctcagtaa tgaaaatgtt gatgtgcaga acggctggcg cgatcagcaa gaaacattac
    22921 tgacttacct gcaaagcggc aatctgcata gcctgcgaac gtggatcaaa gagcgcggtc
    22981 aggattaccc cgcccagaca ctcaccacgc acctgtttat tcctctgcgc cgacgacttc
    23041 agtgccaaca accgactctc caggcgctgc tggcgattct cgacggcgta ctgatcaact
    23101 acatcgccat ttgcctggct tcggcacgta aaaaacaggg taaagatgcg ctggtggttg
    23161 gctggaatat tcacgatacc acccgtctgt ggctggaggg ctggattgcc agtcaacaag
    23221 gatggcgcat tgatgtcctc gcccactcgc tcaatcaact acgccctgaa ctgttcgaag
    23281 gccgtacatt gctggtgtgg tgcggtgaaa atcgaacctc tgcccaacag cagcaactca
    23341 ccagttggca ggaacaaggc catgatattt tcccactcgg catttaatga ttcgttaaca
    23401 aatgcgcttt actgtacaat cctttcgtta acataaggag tgcattatgc gcatagctaa
    23461 aattggggtc atcgccctgt tcctgtttat ggcgttaggt ggaattggtg gcgtcatgct
    23521 cgcaggttat acctttattt tgcgtgctgg ctaagtgcct gcaccagcct ttcaaacagg
    23581 cggtctgcga tgatcgccgc cagtgccacc agtaacgccc cctggatcac atacgcggta
    23641 ttaaatccgc taagcccgat gatgatcggc gtacccagcg tgctggcccc taccgttgag
    23701 gcgatcgtcg ccgtaccaat gttgataatc accgaagttc gcacgcccgc cagaatcacc
    23761 ggagccgcca gcggtagctc gaccttacgc agtcgctgac cacgactcat tcccatacct
    23821 ttcgcaactt ctgtcacgct ggcatcaatc gctcccagcc cggcaagtgt cgcctgcagg
    23881 acgggcagca cgccgtaaag gatcaaggcg ataatcgcgg gttgcagacc aaagccgatc
    23941 accggaacgg caatcgccag cactgcaacg ggcggaaaag tctgcccaac ggcggcaata
    24001 gtttccacca gtgggcgaaa ttccgcgccc cacgggcgag tgaccgcaat tccggcacca
    24061 gtaccaatga tcaccgcaaa caaactcgaa attcccacca gccagaaatg agccagtgcc
    24121 agagctgcaa aactctcttg ctgataaacg ggtcgtggca gttgtgggaa caaggcagca
    24181 aacagcggct ggctgtaagg tagccagaaa atcagcacca caaacagagc aatcagccag
    24241 aacagcggat cgcgcaacat cttcatacgc ttacgcctcc tccagcagat cctgaaaatg
    24301 cagcgtgccg caaggctggc cctgcgtgtt caccaccggc agcacctcgc atccccgcgc
    24361 gacaaacaga gaaagcgcat cgcgtagcgt catctcttct gccagtgcct caccttctgc
    24421 ccgttcttcg cgacgcacgt aatccgccac actacgtaac gaaagcaggc gcacacccag
    24481 ttcactacgt ccaaaaaact ggcggacaaa atcattcacc ggacgagtca gcatcgtcag
    24541 cggattaccc tgctgcacca cttcaccgtg atccatcaat acaagatgtt ctgccagccg
    24601 tagcgcctca tcaatatcat gagtgaccag cacaatagta cgccccagca aacggtgaat
    24661 gcgcgtcatc tcttgttgca acgcaccgcg cgttaccggg tccagtgcgc caaaaggttc
    24721 atccatcagt aagacttgcg gatcggcagc cagtgcgcgc gccactccca cacgttgctg
    24781 ctgaccaccg gaaagctgat gcggataacg ctcacgtaaa tttgactcca gccccagtag
    24841 cgccattaat tcgtcgatac gatcgtcaat cctcgcccgc gaccattttt gtaattgcgg
    24901 cacggtagcg atgttttgcg ccacgctcca gtgggggaac aggccaatag attgaatggc
    24961 atagcccatc cggcggcgca actccagtac tggcagcgag cgaatttctt ctccggcaaa
    25021 gcggatcacg ccgctgtcat gctccaccag gcggttaatc attttcaggg tggtggattt
    25081 gccggagcca gatgtgccaa tcagcaccga aaaactccct tcctgaaaat tgagattgag
    25141 atcgttaacg gctttttgtg cgccgaacag tttgctgaca tggctaaatt caatcattac
    25201 gtttcacctt cagcagtgcg ataagcaaat cgaacagcgc gtcggtaagc accgccagaa
    25261 caattaccgg gatcaccccc agcaacacta aatcaatggc actgcttagc agcccctgga
    25321 aaaccagcgc accaaaaccg cctgcaccga ttaacgccgc aatcaccgcc atacctacag
    25381 tttgcaccat caccacccgc aggctgcgca gaaataccgg taacgccagc ggtaactgaa
    25441 catgcaggaa tcgctgcgcc ccgctcatcc ccatcgctct ggcgctctcc agcacatcgc
    25501 gcgggatctg gttcaagccg actaccacgc cgcgcaccag cggcagcaag gcatagagca
    25561 ccagcgcaat cagtgcgggt gtcattccgg ttcctgctat gcccagctta cccagccacg
    25621 gaaaggccgt aaccagcgcg gcaagcggcg caatcaacag gccaaagagc gccaccgaag
    25681 gcacggtctg aatgacattg agtagcgaaa aaatcgcccc ctgccgcgca gtggaaaagt
    25741 agcaccagac gcccagcggc acaccaatca ctaacgcagg cagcaccgca ccaaacagca
    25801 acgtcagatg ttgtgccagc gcgtcatcaa acacatcctg acggttggcg tattctttca
    25861 ttagcgagag atcgttaagc gcgccggaat acagcaacca cagcggaatg atggcaatct
    25921 gcatatgcaa caaccagcgc cacagcggat gcgtggagat tcgtcggatg gcatcgctac
    25981 aggcaagcaa tgccagcgcc gcagccagcc agaaaccact gccgaggctg gtacgcgcca
    26041 gcgcactgcc attttgcgcc agttgggtcg ccgcttttcc cgctccccac accagcaata
    26101 cgaagacgag ttgcgccagg atgagtgcaa aaatgctgcc ttttttagcg ggaataaaac
    26161 aggctgtcag ccaggcgcaa catacgccca ccagcatcca gatcgtttgc ggccacagct
    26221 gccagagatg acgcccctca cccgaaacta aacgattagg cgcgtaactg ataaacggca
    26281 gcgccgctgc gattgccgtc agcaacagca gcagcgccag aacaggatta atacgtagat
    26341 aagtcacggg aaattacttc gtccaccctt tttgtttcag gtagtcggca gccacttttt
    26401 tggcatccag tccttcaact gcaatgctgg cattcagttg ctgcaatgtt ttttcatcga
    26461 ggctggcgaa gactggctgt agccactgtg ccatttgcgg atactccttc aacaccgatt
    26521 cacgaaccac tggtgcaggc gcgtagatag gttgcacgcc ttgcggatcg cttaaggttt
    26581 gcaaccccag tgccgcgacc ggaccgtcag tgccgtaagc cattgcggca ttaacgccag
    26641 aagtttgctg ggcagcggct ttaatcgtca ccgccgtgtc gccaccagcc agtgacagta
    26701 actgatcctg atcgagttta aagtcgtagg ctttttcaaa cgcgggtaac gcatcggcgc
    26761 gttcgataaa ctctgccgag gctgccagtt tgaaggtgcc gccctctttc agataacgac
    26821 tcaggtcagc aagcgaagtg agtttgtttt tctctaccac atcctgacgc acggcgatgg
    26881 tccaggtgtt atttgcaggc gcgggcgtca gccagattaa cttgttttgc tctgcatcga
    26941 gttttttgac tttctcatag ccttgctgcg cgtttttcca tgccgtatcg ttttcatctt
    27001 taaagaaaaa cgcgccattg ccagtatatt ccggatagat atccagctca ccagaagtga
    27061 tcgccccgcg cactacggga gtcgttccca attgcacttt atttaccgta ggaacgccgt
    27121 gactttccag cacctgcaaa atgatattgc cgagcagcgc gccttcggta tcgatttttg
    27181 aaccgacttt aacgggggaa gccgcctgta gcggcaggct cacggctgcc aacaaaacca
    27241 gtgaacctgc ccagaccttt gagagtggca tgatgctttc ctcattcttt tactgttgtt
    27301 ttcagcgaat taagagaaaa gcatagttga taatggcggg gttagcctga gcggaaggat
    27361 tcagttgcag aatcagataa atacttaaag ggcatatttt gcccggcgtt tcttgccgga
    27421 tgcggcgtaa acgccttatc cggcctacaa acagcgaaaa ttcaagaggt taaaaacccc
    27481 tgtaggcctg ataagcgcaa cgcatcaggc aaagggcgca aacatcgcgc cctgactaaa
    27541 gtattacagc aattcaaact cgcctttctt aacgcgtgcg gaatcagtgc cgataaagac
    27601 attgaacttg ccaggctcgg cgtcatattt catctgttga ttccagaact tcagcgcctc
    27661 gatatcaatc gggaagctga cggtctgggt ttcgcccggt ttcagggtga ttttctcaaa
    27721 gcctttcagc tgttttaccg ggcgactcat ggaagccgtc acatcctgca ggtacatctg
    27781 aactaccgtc gccccttcgc gcttaccggt gttcgtcacc tgcacgctgg cggtcacttt
    27841 gccgtcacgc ttcatggtcg gcgcagaaag tttcacatca gagacggtga aagtggtata
    27901 gctcagacca tagccgaacg gataaagcgc cccgttagct tcatcaaaat aacgcgaagt
    27961 gtatttgttc ggcttgtcgg cattatacgg gcgaccggta ttcagatgac tgtagtacac
    28021 cgggatctgc ccgacagaac gcgggaagga catcggcagc ttgccggacg ggttgtaatc
    28081 gccaaacaat acatcggcaa ttgcattacc gccttcagtc cccgcaaacc aggtttccag
    28141 aatcgcatcc gcctgctgat cttctttcac cagcgccagc ggacgcccgt tcatcagcac
    28201 cagcaccagc ggtttaccgg tggctttcag cgccgcaatc aagtcacgtt ggctttgcgg
    28261 aatagtgata tcggtacggc tggaggcctc gtgcgccatc ccctgagctt caccgaccac
    28321 agccaccacc acatcagatt gcttcgcggt ttgcaccgct tcatcaatca tctcttgcgg
    28381 cgagcgcggg tcgactttga ccgcctcttc atactgattc aggaaatcga taatgccttt
    28441 gtcactggtg acgttcgccc ctttggcgta caacacttta ccgttttcac cgacggcatt
    28501 tttaatcccg gtcagtacgg tcacggattg atcggcaaca ccggctgcgg accagctgcc
    28561 catcacgtca cgtttgctgt ccgccaatgg cccaaccacc gcaatggtgg ctgatttttt
    28621 cagcggtaac gtttcgagac ggtttttcag caacaccagg ctttcgcgtg ccacttcacg
    28681 cgcttctttg cggtgcaggc ggctttcggc attggtatcc accggggcag actctttcgg
    28741 accgagatgg ctgtacgggt cgttaaacaa ccccatatca tatttaacgt tcagtacatg
    28801 acgggcagcg tcatccagct cttccatcgt cactttgccg gatttgatca acccaggcag
    28861 atacttcgag taatactcgt cgctcatact catgttgatg ccggatttca gcgccacgcg
    28921 caccgcatct tccgggtctg ccgctgtgcc atgtttaatc agctctttga ttgcgccgtg
    28981 atcggaaacg gtgatgcctt taaagcccca ctggtcgcgc aggacatctt tcagcagcca
    29041 ggaatcggag gtggctggcg tgccgttcag cgagttcagc gccaccatca ccgcgccgct
    29101 gcctgcgtcc agccccgctt tgtacggcgg catataatca ttaaacaggc gctgcggact
    29161 catatcgacg gtgttgtact ctttaccgcc ttctaccgcg ccgtaagcgg caaagtgttt
    29221 gacgctggtc atcaccgagt agcgatctgc cggactttta ccctgcatcg cttgcaccat
    29281 ggttttaccc attattgagg tgagatacgt atcttcgcca aaaccttcgg aagcacgtcc
    29341 ccagcgcgga tcgcgcgaga catcgaccat cggtgcccag gtcatattca ggccatcatc
    29401 tgccgcttca taagcagaga cacgcccgac tgttttcact gcatcgaggt taaaagacga
    29461 ggccagaccg agactaatcg ggaacaccgt gcgctgaccg tgcagcacgt cgtaagcaaa
    29521 gaaaagagga attttcaggc ggcttaattc catcacctga tcctgcatgg cgcggatatc
    29581 ctgacgggtt acggtgttga aaatcgcccc aacctgaccg tctttgatca tctcgcggat
    29641 cgcctctttc gggttatccg ggccgacgct gattaagcgc agctgaccaa ttttctcatc
    29701 aactgtcatt ttcttaagca gttcggtgac gaacgcatcc cgcgcttcgg gcgttaatgg
    29761 atggttgccg aataaatcat ccgccagtgc tggctgcagg gccagactca ccgcgattcc
    29821 tactgaacat agccatttca tatggatttt tcttcctttg ttgcccgacg tggcagcgaa
    29881 aatggtgcaa aaaccgtagt ttgccataag catgatggag agagaaaaag aatgctcagt
    29941 ttattgtctg aattttcaaa atattcactc gctgaattgt catacaaggc gctattctag
    30001 tttgtgatat tttttcgcca ccacaaggag tggaaaatgt cttccatgac aacaactgat
    30061 aataaagcct ttttgaatga acttgcccgt ctggtcggtc attcacacct gctcaccgat
    30121 cccgcaaaaa cggcccgcta tcgcaagggc ttccgttctg gtcagggcga cgcgctggct
    30181 gtcgttttcc ctggctcact actggaattg tggcgggtgc tgaaagcctg cgtcaccgcc
    30241 gacaaaatta ttctgatgca ggccgccaat acaggtctga ccgaaggctc gacgccaaac
    30301 ggtaacgact atgatcgcga tatcgtgatc atcagcaccc tgcgtctcga taagttgcac
    30361 gttctcggca agggcgaaca agtgctggcc tatccgggca ccacgcttta ttcgctggaa
    30421 aaagcactca aaccgctggg acgcgaaccg cactcggtga ttggatcatc gtgtataggc
    30481 gcatcggtca tcggcggtat ttgtaacaac tccggcggct cgctggtgca gcgtggcccg
    30541 gcgtataccg aaatgtcgtt attcgcgcgt ataaatgaag acggcaaact gacgctggtg
    30601 aaccatctcg ggattgatct gggcgaaacg ccggagcaga tccttagcaa gctggatgac
    30661 gatcgcatca aagatgacga tgtgcgtcac gatggccgtc acgcccacga ttatgactat
    30721 gtccaccgcg ttcgtgatat tgaagccgac acgcccgcac gttataacgc cgatccggat
    30781 cggttatttg aatcttctgg ttgcgccggg aagctggccg tctttgcggt acgtcttgat
    30841 accttcgaag cggaaaaaaa tcagcaggtg ttttatatcg gcaccaacca gccggaagta
    30901 ctgaccgaaa tccgccgtca tattctggct aatttcgaaa atctgccggt tgccggggaa
    30961 tatatgcacc gggatatcta cgatattgcg gaaaaatacg gcaaagacac cttcctgatg
    31021 attgataagt taggcaccga caagatgcca ttcttcttta atctcaaggg gcgcaccgat
    31081 gcgatgctgg agaaagtgaa attcttccgt ccccatttta ccgaccgtgc gatgcaaaaa
    31141 ttcggtcacc tgttccccag ccatttaccg ccgcgcatga aaaactggcg cgataaatac
    31201 gaacatcatc tgctgttaaa aatggcgggc gatggcgtcg gtgaagccaa atcgtggctg
    31261 gtggattatt tcaaacaggc cgaaggcgat ttctttgtct gtacgccgga ggaaggtagc
    31321 aaagcgtttt tacaccgttt cgccgctgcg ggcgcagcaa ttcgttatca ggcggtgcat
    31381 tccgatgaag tcgaagacat tctggcactg gatatcgctc tgcggcgtaa cgacaccgag
    31441 tggtatgagc atttaccgcc ggagatcgac aaccaactgg tgcacaagct ctattacggc
    31501 cattttatgt gctatgtctt ccatcaggat tacatcgtta aaaaaggcgt ggatgtgcat
    31561 gcgttgaaag aacagatgct ggaactgctg cagcagcgtg gcgcgcaata ccctgccgag
    31621 cataacgtcg gtcatttgta taaagcaccg gagacgttgc agaagttcta tcgcgagaac
    31681 gatccgacca acagtatgaa tccggggatc ggtaaaacca gtaagcggaa aaactggcag
    31741 gaagtggagt aaaaattacg gatggcagag tatcgccatc cgtacttcac ttaatcgttc
    31801 tgcgccgtct gccccgccgc cgccatctgg gcggcttttt gttttttata gctcaacgct
    31861 gctgccggaa caggcatcac tttaccggtc tcaatccagg tacgcaggcg gctggcatcg
    31921 gcaaaatggg tatatttgcc aaacgcgtcc attactacca gcgccaccgg tttattattg
    31981 ataaccgtac gcatcaccag acaatggccc gccgcattgg taaagccggt tttggttaac
    32041 tgaatattcc agttatcgcg atacaccaga tggttagtat tgcggaacgg cagcgtatac
    32101 gtcgggttag agaaggttgc catatcttcc cgggtggtac ttaactgccc gatcaacgga
    32161 tattgtttgc tggcaatgag cagtttggtt aagtcacggg cagttgaaac gttatgcacc
    32221 gacaatccgg taggttcaac aaagcgcgtg ttgttcattc cgagcgattt cgctttcgca
    32281 ttcattgcct taataaaggc tttgtaacca ccgggataat ggtgcgcaag gcttgccgcc
    32341 gcgcggtttt ctgaagacat cagcgccagc aacagcatat ctttacggct gatttcgctg
    32401 ttcagtcgta cgcgcgaata gacccctttc atctccggcg tctggctgat atccactttt
    32461 agtttttcat ccagcggcag tcgtgcatcc agcacaacca tcgcggtcat taatttgctg
    32521 atagacgcaa tcggacgcac cagatccggg tggttcgaat agatcacttt gttggtattc
    32581 agatcaacaa tcatcgcgct accggaggca atttccggct gtgaagcggt ggtagcggct
    32641 gccgttttcg caacggcctg cggtgccaaa ggcacagcca gcatcagggc caggctaaat
    32701 aaagaaactc gaaatttcgg catgatgagc attcagatag tggttcacgc gcacgggttg
    32761 cgcaccgccg gagtaaggat ttactgaggc tagcgacgcc atcataacga gcaaaaagtg
    32821 cgatcgtcaa aggagaatcg tgaggaaatg ctgcattgct gacatttacg ccagcaatgc
    32881 aactcaaaag aactttctag aacaaacgat aaccgtagcc ccatagtata acggtaaggg
    32941 cgagcagcac ttccagcacc agcacgccta tcgccagcgt cgaactggag aagctaagtc
    33001 cttcctcttt gttgatattc aggaagctcg gaataccgag atacagcagg tagccggtgt
    33061 aaaacagcgc caccgtgccg accagcgcac acaaccagac cagcgggtaa agcgccacca
    33121 gaccgcttaa aaacagcgga gttgcaacgt agcccgcgaa gaccatgcag tgcgcaagtg
    33181 acggacgctg cgggtaattg cgcgccatcc accagatgac ccgccccatc accgcgaccc
    33241 cagccagcat aacgccataa aacaagacag ccagcgccag tccggtaaac caggataact
    33301 tcaggatagt gccatcgcca aaattccagc caatctgtgt agtgccaatg aaggcgcaaa
    33361 tcaccggaat cgccgccatc agcaaaacgt ggtgggtgta gtgatgagaa atcgtttcgt
    33421 tttcgcgatt aatcacctgc atttcacgat cgggatggga aaacagtccc cagacatggc
    33481 tcataccgcc cccttgttgt gagttcatga acctgacagt tcaagtataa gtcagcttgt
    33541 gattattttt tgttcgctca tgtaatttgc accgtctgat gtacgtcctt tttcagcgtg
    33601 aatgattcac agggtgtatg cttacaggca agcaaaggga gacagactgt cctatggatc
    33661 tcaatacact catctcacaa tatggttatg ccgcgctggt tatcggtagc ctggcggaag
    33721 gtgaaaccgt gactttgctg ggaggcgttg cggcacatca ggggctatta aagttcccgc
    33781 tggtggtact ttctgtggcg cttggcggca tgattggcga ccaggtgctt tatctgtgcg
    33841 ggcggcggtt tggcggcaag ctgttacgcc gtttctcgaa acatcaggat aaaattgagc
    33901 gggcgcagaa acttatccaa cgccatccgt atctgtttgt cattggtacg cgttttatgt
    33961 atggctttcg ggtcattggc ccgacgctga ttggtgccag ccagctgccg ccgaaaatct
    34021 ttctgccgct gaatattctc ggcgcatttg cctgggcgct gatttttacc actatcggtt
    34081 acgctggtgg gcaggtgatt gcgccgtggt tgcacaatct cgaccagcat ttgaagcact
    34141 gggtctggtt gattctggtc gtggttctgg tggtaggcgt gcgctggtgg ctgaaacggc
    34201 gcgggaagaa aaagccggat catcaggcgt aaagcagttg ccacagataa gcattcacgc
    34261 cacatccggc accggatgtt ccatgcctga tgcgacgctg gcgtgtctta tctggcctaa
    34321 cccattgaaa taaccacgcg cctcactgcg ctattctggg ttgaactgcg gattcgccaa
    34381 cataaagccg ccatccacta tcaacgactg cccggtggtg taatttgcgc cctccgaaca
    34441 aagccatacc accaggctgg caatctcatg cgttgtgcca aaacgtcgca agggaatcga
    34501 aggctccgcg tcaggcttca cgtcgccgcc atccatgccg ttcattggcg tggcgatcgc
    34561 cccaggtgcg actgcgttca ccaaaatttt atgcctgacc aactccagcg ccattgcttt
    34621 ggttaacccg ccgagcgcat gtttagcggc tgtgtaggcg ctggcatccg gcagcggcgt
    34681 atgttcatgt accgatgtaa tgttgatgat gcgaccgccc tgcccttgct tcaccatctg
    34741 gcgggcagca atttgcgagc ataaaaatgc accatcgaca tcaacggtaa aaatcttgcg
    34801 ccactcatcg aaagccatat caagaaacgg cgctttggtc attgcgcccg cattattcac
    34861 cagcacatcg atgcgcccca gtcgatgaat gagtttctcc agcgcctgcg caccttctgg
    34921 cagattaccg agatccagct gcacgatctc cgcacgtacg ccgtggctaa ccacctcacg
    34981 cgcagtatct tttgcccctt cttcatctga gtgccaggta ataccaatat caaacccctg
    35041 ctgcgccagt aataacgcgc actctttgcc gatccccgaa tcggaggcgg taattatcgc
    35101 gacctgtgcc atcgagttct ccacttaacg ctgaataaat gttaagtata gaaggcgcat
    35161 atcatcagcg tttgtaaccc ccgcccagcg caccggtgag ttgaatggag gcatccagcc
    35221 actgcccttg caataacaag ccattggccc gctcacgcag cgcggggatt ctggcttcgc
    35281 tgacgcggga accagcaatg atgcccgcgt taaagcgcgc ctgcgcaaga cctaccacac
    35341 gcaaggcatc gtgctcaatt tgcgcctgat gctggttttt ctccgccagt gtctgaacct
    35401 ggctggccgc ccgcgccacg tcattcaccg cttcaaccac cgctttgttg tagctggcga
    35461 tagacaagtt gctttcggct tttgcgatat cgaggttggc gttaagacga ccactatcga
    35521 aaatgggtag cgtcaggcct gccgtaacgc ccatttgctg cgcggaatga cggaacagat
    35581 cgcttaagtg caacgcatcc tgttgcagga aggccatcag gttgatgtca ggataaaatg
    35641 ccgcttttgc cgcatcaatg gtgcttagcg atgactcaac gtaccagtgc gccgcctgca
    35701 aatctgcccg ccgcgccagt aaggagtacc ccagttcatc aggaagctgg cttgccactt
    35761 tcggcaacgc gaccggatta agcttcaatg cctttgtctg gtgatttgta agtgcgctta
    35821 accgtgcctc aataattttc attttccccg cgacatcgtt gagctgctgc cgggttttgc
    35881 tggcattaat atcggtttcc acaccttcaa ctgaagaagt aatcccgttc tgatatagct
    35941 ggcgatcggt ggcgataatg gtgttctgct ctttttcgat ttgctgcaag accgtgttta
    36001 acgccgcctg ggtttgccac tcccagtaca ggcgggctac gctgccagcc agcaattggc
    36061 gggtttgctc gcgttccgcc acccgtgctt taaccgtacc caggcgagca gttacctccg
    36121 cccgattctt tccccagata tcgagatgcc agcccgccgt taagccaaaa gtaccgttgg
    36181 tgtaccacgg accggtcgta cctgcggcag gatcgttcaa agcaaacggc cccattaacc
    36241 cttctgccga cattttttgc cgctccatat ccgcagaaaa gtcgagctgt ggaccatcct
    36301 gagtggcaac tgccttcgcc tgggcttcag ccagctgaat gcgctgttca gccacctgca
    36361 tatccggtgc gttctgtagt gcgttattaa ttaatgaggt gagttgatta tcgtgatact
    36421 ccagccacca ttggctgtct ggccaaccat ttttcagcgc cgtgggtaat gcggtgtcaa
    36481 cttgtgccgc gggtgtttgc tggcttaacg cctggcgggt ttcatgcata ggcgcacacc
    36541 cggctagcat cagtaacagc ggaaaacagg cgatggctgg ataaaaagaa tcacgattca
    36601 tgggggaata atcaggtaag aaaaggtgcg cggagattac cgtgtgttgc gatatatttt
    36661 ttagtttcgc gtggcaatac atcagtggca ataaaacgac atatccagaa aaatatacac
    36721 taagcgaatg atatcttccg atttatctta atcgtttatg aatagcggca aagggcttcg
    36781 ttttttccta tacttattca gcactcacaa ataaaggaac gccaatgaaa attatactct
    36841 gggctgtatt gattattttc ctgattgggc tactggtggt gactggcgta tttaagatga
    36901 tattttaaaa atcagatatg gcatataagt tgtcaggtca gtaactcgat attttgtgta
    36961 cttgatttgc aaacagctcc ggtgttggtg gcgtcaaaat cgctgaagcg ttccccgaag
    37021 gccggggcag cccacatgga tgtgggctga gggcgcgtct taca
//
LOCUS       DADXDL010000045        37046 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.045, whole genome shotgun sequence.
ACCESSION   DADXDL010000045 DADXDL010000000
VERSION     DADXDL010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37046)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37046)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37046
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.045"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(20..1192)
                     /gene="cgtA"
                     /locus_tag="IRB70_002532"
     CDS             complement(20..1192)
                     /gene="cgtA"
                     /locus_tag="IRB70_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Obg family GTPase CgtA"
                     /protein_id="HBC0632435.1"
                     /translation="MKFVDEASILVVAGDGGNGCVSFRREKYIPKGGPDGGDGGDGGD
                     VWMEADENLNTLIDYRFEKSFRAERGQNGASRDCTGKRGKDVTIKVPVGTRVIDQGTG
                     ETMGDMTKHGQRLLVAKGGWHGLGNTRFKSSVNRTPRQKTNGTPGDKRELLLELMLLA
                     DVGMLGMPNAGKSTFIRAVSAAKPKVADYPFTTLVPSLGVVRMDNEKSFVVADIPGLI
                     EGAAEGAGLGIRFLKHLERCRVLLHLIDIDPIDGTDPVENARIIISELEKYSQDLAAK
                     PRWLVFNKIDLLDKAEAEEKAKAIAEALGWEDKYYLISAASGLGVKDLCWDVMTFIIE
                     NPVVQAEEAKQPEKVEFMWDDYHRQQLEEIAEEDDEDWDDDWDEDDEEGVEFIYKR"
     gene            complement(1208..2173)
                     /locus_tag="IRB70_002533"
     CDS             complement(1208..2173)
                     /locus_tag="IRB70_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012135318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBC0632436.1"
                     /translation="MKQQAGIGILLALTTAICWGALPIAMKQVLEVMEPPTIVFYRFL
                     MASIGLGAILAVKKRLPPLRVFRKPRWLILLAVATAGLFGNFILFSSSLQYLSPTASQ
                     VIGQLSPVGMMVASVFILKEKMRSTQVVGALMLLSGLVMFFNTSLVEIFTKLTDYTWG
                     VIFGVGAATVWVSYGVAQKVLLRRLASPQILFLLYTLCTIALFPLAKPGVIAQLSHWQ
                     LACLIFCGLNTLVGYGALAEAMARWQAAQVSAIITLTPLFTLFFSDLLSLAWPDFFAR
                     PMLNLLGYLGAFVVVAGAMYSAIGHRIWGGLRKHTTVVSQPRAGE"
     gene            complement(2300..2557)
                     /gene="rpmA"
                     /locus_tag="IRB70_002534"
     CDS             complement(2300..2557)
                     /gene="rpmA"
                     /locus_tag="IRB70_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004933559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBC0632437.1"
                     /translation="MAHKKAGGSTRNGRDSEAKRLGVKRFGGESVLAGSIIVRQRGTK
                     FHAGANVGCGRDHTLFAKADGKVKFEVKGPKNRKFISIEAE"
     gene            complement(2578..2889)
                     /gene="rplU"
                     /locus_tag="IRB70_002535"
     CDS             complement(2578..2889)
                     /gene="rplU"
                     /locus_tag="IRB70_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015960603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBC0632438.1"
                     /translation="MYAVFQSGGKQHRVSEGQTVRLEKLDIATGETVEFAEVLMIANG
                     EEVKIGVPFVDGGVIKAEVVAHGRGEKVKIVKFRRRKHYRKQQGHRQWFTDVKITGIS
                     A"
     gene            3148..4119
                     /gene="ispB"
                     /locus_tag="IRB70_002536"
     CDS             3148..4119
                     /gene="ispB"
                     /locus_tag="IRB70_002536"
                     /EC_number="2.5.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="octaprenyl diphosphate synthase"
                     /protein_id="HBC0632439.1"
                     /translation="MNLEKINELTAQDMAGVNAAILEQLNSDVQLINQLGYYIVSGGG
                     KRIRPMIAVLAARAVGYEGNAHVTIAALIEFIHTATLLHDDVVDESDMRRGKATANAA
                     FGNAASVLVGDFIYTRAFQMMTSLGSLKVLEVMSEAVNVIAEGEVLQLMNVNDPDITE
                     ENYMRVIYSKTARLFEAAAQCSGILAGCTPEEEKGLQDYGRYLGTAFQLIDDLLDYNA
                     DGEQLGKNVGDDLNEGKPTLPLLHAMHHGTPEQAQMIRTAIEQGNGRHLLEPVLEAMN
                     ACGSLEWTRQRAEEEADKAIAALQVLPDTPWREALIGLAHIAVQRDR"
     gene            4348..4626
                     /gene="sfsB"
                     /locus_tag="IRB70_002537"
     CDS             4348..4626
                     /gene="sfsB"
                     /locus_tag="IRB70_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SfsB"
                     /protein_id="HBC0632440.1"
                     /translation="MESNFIDWHPADIIAGLRKKGTSMAAESRRNGLSSSTLANALSR
                     PWPKGEMIIAKALGTDPWIIWPSRYHDPQTHEFIDRTQLMRSYTKPKK"
     gene            complement(4674..5933)
                     /gene="murA"
                     /locus_tag="IRB70_002538"
     CDS             complement(4674..5933)
                     /gene="murA"
                     /locus_tag="IRB70_002538"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBC0632441.1"
                     /translation="MDKFRVQGPTKLQGEVTISGAKNAALPILFAALLAEEPVEIQNV
                     PKLKDVDTSMKLLSQLGAKVERNGSVHIDARDVNVFCAPYDLVKTMRASIWALGPLVA
                     RFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIVMDK
                     VSVGATVTIMCAATLAEGTTIIENAAREPEIVDTANFLITLGAKISGQGTDRIVIEGV
                     ERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG
                     EDWISLDMHGKRPKAVNVRTAPHPAFPTDMQAQFTLLNLVAEGTGFITETVFENRFMH
                     VPELSRMGAHAEIESNTVICHGVEKLSGAQVMATDLRASASLVLAGCIAEGTTVVDRI
                     YHIDRGYERIEDKLRALGANIERVKGE"
     gene            complement(5988..6242)
                     /gene="ibaG"
                     /locus_tag="IRB70_002539"
     CDS             complement(5988..6242)
                     /gene="ibaG"
                     /locus_tag="IRB70_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417657.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BolA family iron metabolism protein IbaG"
                     /protein_id="HBC0632442.1"
                     /translation="MENNEIQSVLMNALSLQEVHVSGDGSHFQVIAVGELFDGMSRVK
                     KQQTVYGPLMEYIADNRIHAVSIKAYTPAEWARDRKLNGF"
     gene            complement(6402..6695)
                     /gene="mlaB"
                     /locus_tag="IRB70_002540"
     CDS             complement(6402..6695)
                     /gene="mlaB"
                     /locus_tag="IRB70_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance protein MlaB"
                     /protein_id="HBC0632443.1"
                     /translation="MSESLSWMQTGDTLALSGELDQDVLLPLWEIREEAVKGITSIDL
                     SRVSRVDTGGLALLLHLIDLAKKQGNNVTLQGVNDKVYTLAKLYNLPADVLPR"
     gene            complement(6695..7330)
                     /gene="mlaC"
                     /locus_tag="IRB70_002541"
     CDS             complement(6695..7330)
                     /gene="mlaC"
                     /locus_tag="IRB70_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid-binding protein MlaC"
                     /protein_id="HBC0632444.1"
                     /translation="MFKRLMMVALLVIAPLSAATAADQTNPYKLMDEAAQKTFDRLKN
                     EQPQIRANPDYLRTIVDQELLPYVQVKYAGALVLGQYYKSATPAQRDAYFAAFREYLK
                     QAYGQALAMYHGQTYQIAPEQPLGDKTIVPIRVTIIDPNGRPPVRLDFQWRKNSQTGN
                     WQAYDMIAEGVSMITTKQNEWGTLLRTKGIDGLTAQLKSISQQKITLEEKK"
     gene            complement(7349..7900)
                     /gene="mlaD"
                     /locus_tag="IRB70_002542"
     CDS             complement(7349..7900)
                     /gene="mlaD"
                     /locus_tag="IRB70_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipid asymmetry maintenance
                     protein MlaD"
                     /protein_id="HBC0632445.1"
                     /translation="MQTKKNEIWVGIFLLAALLAALFVCLKAANVTSIRTEPTYTLYA
                     TFDNIGGLKARSPVSIGGVVVGRVADITLDPKTYLPRVTLEIEQRYNHIPDTSSLSIR
                     TSGLLGEQYLALNVGFEDPELGTAILKDGDTIQDTKSAMVLEDLIGQFLYGSKGDDNK
                     NSGDAPAAAPGNNETTEPVGTTK"
     gene            complement(7905..8687)
                     /gene="mlaE"
                     /locus_tag="IRB70_002543"
     CDS             complement(7905..8687)
                     /gene="mlaE"
                     /locus_tag="IRB70_002543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014071945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid asymmetry maintenance ABC transporter
                     permease subunit MlaE"
                     /protein_id="HBC0632446.1"
                     /translation="MLLNALASLGHKGIKTLRTFGRAGLMLFNALVGKPEFRKHAPLL
                     VRQLYNVGVLSMLIIVVSGVFIGMVLGLQGYLVLTTYSAETSLGMLVALSLLRELGPV
                     VAALLFAGRAGSALTAEIGLMRATEQLSSMEMMAVDPLRRVISPRFWAGVISLPLLTV
                     IFVAVGIWGGSLVGVSWKGIDSGFFWSAMQNAVDWRMDLVNCLIKSVVFAITVTWISL
                     FNGYDAIPTSAGISRATTRTVVHSSLAVLGLDFVLTALMFGN"
     gene            complement(8695..9504)
                     /gene="mlaF"
                     /locus_tag="IRB70_002544"
     CDS             complement(8695..9504)
                     /gene="mlaF"
                     /locus_tag="IRB70_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospholipid ABC transporter ATP-binding protein
                     MlaF"
                     /protein_id="HBC0632447.1"
                     /translation="MEQSVANLVDMRDVSFTRGNRCIFDNISLTVPRGKITAIMGPSG
                     IGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNV
                     FDNVAYPLREHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIA
                     LEPDLIMFDEPFVGQDPITMGVLVKLISELNSALGVTCVVVSHDVPEVLSIADHAWIL
                     ADKKIVAHGSAQALQANPDPRVRQFLDGIADGPVPFRYPAGDYHADLLPGS"
     gene            9714..10691
                     /locus_tag="IRB70_002545"
     CDS             9714..10691
                     /locus_tag="IRB70_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312102.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="calcium/sodium antiporter"
                     /protein_id="HBC0632448.1"
                     /translation="MLLATALLIVGLLLVVYSADRLVFAASILCRTFGIPPLIIGMTV
                     VSIGTSLPEIIVSLAASLHEQRDLAVGTALGSNIINILLILGLAALVRPFTVHSDVLR
                     RELPLMLLVSVVAGSVLYDGQLSRSDGIFLLFLAVLWLLFIVKLARQAERQGTDSLTR
                     EQLAELPRDGGLPVAFLWLGIALIIMPVATRMVVDNATVLANYFAISELTMGLTAIAI
                     GTSLPELATAIAGVRKGENDIAVGNIIGANIFNIVIVLGLPALITPGKIDPLAYSRDY
                     SVMLLVSIIFALLCWRRSPQSGRGVGVLLTGGFIVWLAMLYWLSPILVE"
     gene            10705..11691
                     /gene="kdsD"
                     /locus_tag="IRB70_002546"
     CDS             10705..11691
                     /gene="kdsD"
                     /locus_tag="IRB70_002546"
                     /EC_number="5.3.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose-5-phosphate isomerase KdsD"
                     /protein_id="HBC0632449.1"
                     /translation="MSHVELQPGFDFQQAGKEVLAIERECLAELDQYINQNFTLACEK
                     MFWCKGKVVVMGMGKSGHIGRKMAATFASTGTPSFFVHPGEAAHGDLGMVTPQDVVIA
                     ISNSGESSEITALIPVLKRLHVPLICITGRPESSMARAADVHLCVKVAKEACPLGLAP
                     TSSTTATLVMGDALAVALLKARGFTAEDFALSHPGGALGRKLLLRVNDIMHTGDEIPH
                     VKKTASLRDALLEVTRKNLGMTVICDDNMMIEGIFTDGDLRRVFDMGVDVRQLSIADV
                     MTPGGIRVRPGILAVEALNLMQSRHITSVMVADGDHLLGVLHMHDLLRAGVV"
     gene            11712..12278
                     /gene="kdsC"
                     /locus_tag="IRB70_002547"
     CDS             11712..12278
                     /gene="kdsC"
                     /locus_tag="IRB70_002547"
                     /EC_number="3.1.3.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate-8-phosphatase KdsC"
                     /protein_id="HBC0632450.1"
                     /translation="MSKAGASLATCYGPVSADVMAKAENIRLLILDVDGVLSDGLIYM
                     GNNGEELKAFNVRDGYGIRCALTSDIEVAIITGRKAKLVEDRCATLGITHLYQGQSNK
                     LIAFSDLLEKLAIAPENVAYVGDDLIDWPVMEKVGLSVAVADAHPLLIPRADYVTRIA
                     GGRGAVREVCDLLLLAQGKLDEAKGQSI"
     gene            12275..12850
                     /gene="lptC"
                     /locus_tag="IRB70_002548"
     CDS             12275..12850
                     /gene="lptC"
                     /locus_tag="IRB70_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter periplasmic protein
                     LptC"
                     /protein_id="HBC0632451.1"
                     /translation="MSKARRWVIIVLSLAVLVMIGINMAEKDDTAQVVVNNNDPTYKS
                     EHTDTLVYNPEGALSYRLIAQHVEYYSDQAVSWFTQPVLTTFDKDKIPTWSVKADKAK
                     LTNDRMLYLYGHVEVNALVPDSQLRRITTDNAQINLVTQDVTSEDLVTLYGTTFNSSG
                     LKMRGNLRSKNAELIEKVRTSYEIQNKQTQP"
     gene            12819..13376
                     /gene="lptA"
                     /locus_tag="IRB70_002549"
     CDS             12819..13376
                     /gene="lptA"
                     /locus_tag="IRB70_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide ABC transporter
                     substrate-binding protein LptA"
                     /protein_id="HBC0632452.1"
                     /translation="MKFKTNKLSLNLVLASSLLAASIPAFAVTGDTDQPIHIESDQQS
                     LDMQGNVVTFTGNVIVTQGTIKINADKVVVTRPGGEQGKEVIDGYGKPATFYQMQDNG
                     KPVEGHASQMHYELAKDFVVLTGNAYLQQVDSNIKGDKITYLVKEQKMQAFSDKGKRV
                     TTVLVPSQLQDKNNKGQTPAQKKGN"
     gene            13383..14108
                     /gene="lptB"
                     /locus_tag="IRB70_002550"
     CDS             13383..14108
                     /gene="lptB"
                     /locus_tag="IRB70_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter ATP-binding protein"
                     /protein_id="HBC0632453.1"
                     /translation="MATLTAKNLAKAYKGRRVVEDVSLTVNSGEIVGLLGPNGAGKTT
                     TFYMVVGIVPRDAGNIIIDDDDISLLPLHARARRGIGYLPQEASIFRRLSVYDNLMAV
                     LQIRDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFIL
                     LDEPFAGVDPISVIDIKRIIEHLRDSGLGVLITDHNVRETLAVCERAYIVSQGHLIAH
                     GTPTEILQDEHVKRVYLGEDFRL"
     gene            14156..15589
                     /gene="rpoN"
                     /locus_tag="IRB70_002551"
     CDS             14156..15589
                     /gene="rpoN"
                     /locus_tag="IRB70_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBC0632454.1"
                     /translation="MKQGLQLRLSQQLAMTPQLQQAIRLLQLSTLELQQELQQALESN
                     PLLEQIDTHEEIDTRETQDSETLDTADALEQKEMPEELPLDASWDTIYTAGTPSGTSG
                     DYIDDELPVYQGETTQTLQDYLMWQVELTPFSDTDRAIATSIVDAVDDTGYLTVPLED
                     ILESMGDEEIDIDEVEAVLKRIQRFDPVGVAAKDLRDCLLIQLSQFDKTTPWLEEARL
                     IISDHLDLLANHDFRTLMRVTRLKEDVLKEAVNLIQSLDPRPGQSIQTGEPEYVIPDV
                     LVRKHNGHWTVELNSDSIPRLQINQHYASMCNNARNDGDSQFIRSNLQDAKWLIKSLE
                     SRNDTLLRVSRCIVEQQQAFFEQGEEYMKPMVLADIAQAVEMHESTISRVTTQKYLHS
                     PRGIFELKYFFSSHVNTEGGGEASSTAIRALVKKLIAAENPAKPLSDSKLTSLLSEQG
                     IMVARRTVAKYRESLSIPPSNQRKQLV"
     gene            15612..15899
                     /gene="hpf"
                     /locus_tag="IRB70_002552"
     CDS             15612..15899
                     /gene="hpf"
                     /locus_tag="IRB70_002552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome hibernation promoting factor"
                     /protein_id="HBC0632455.1"
                     /translation="MQLNITGNNVEITEALREFVTAKFAKLEQYFDRINQVYVVLKVE
                     KVTHTSDATLHVNGGEIHASAEGQDMYAAIDGLIDKLARQLTKHKDKLKQH"
     gene            16017..16508
                     /gene="ptsN"
                     /locus_tag="IRB70_002553"
     CDS             16017..16508
                     /gene="ptsN"
                     /locus_tag="IRB70_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS IIA-like nitrogen regulatory protein PtsN"
                     /protein_id="HBC0632456.1"
                     /translation="MTNNDTTLQLSSVLNRECTRSRVHCQSKKRALEIISELAAKQLS
                     LPPQVVFEAILTREKMGSTGIGNGIAIPHGKLEEDTLRAVGVFVQLETPIAFDAIDNQ
                     PVDLLFALLVPADQTKTHLHTLSLVAKRLADKTICRRLRAAQSDEELYQIITDTEGTP
                     DEA"
     gene            16554..17408
                     /gene="rapZ"
                     /locus_tag="IRB70_002554"
     CDS             16554..17408
                     /gene="rapZ"
                     /locus_tag="IRB70_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBC0632457.1"
                     /translation="MVLMIVSGRSGSGKSVALRALEDMGFYCVDNLPVVLLPDLARTL
                     ADREISAAVSIDVRNMPESPEIFEQAMSNLPDAFSPQLLFLDADRNTLIRRYSDTRRL
                     HPLSSKNLSLESAIDKESDLLEPLRSRADLIVDTSEMSVHELAEMLRTRLLGKREREL
                     TMVFESFGFKHGIPIDADYVFDVRFLPNPHWDPKLRPMTGLDKPVAAFLDRHTEVHNF
                     IYQTRSYLELWLPMLETNNRSYLTVAIGCTGGKHRSVYIAEQLADYFRSRGKNVQSRH
                     RTLEKRKP"
     gene            17405..17677
                     /gene="npr"
                     /locus_tag="IRB70_002555"
     CDS             17405..17677
                     /gene="npr"
                     /locus_tag="IRB70_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000216792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS phosphocarrier protein NPr"
                     /protein_id="HBC0632458.1"
                     /translation="MTVKQTVEITNKLGMHARPAMKLFELMQGFDAEVLLRNDEGTEA
                     EANSVIALLMLDSAKGRQIEVEATGPQEEEALAAVIALFNSGFDED"
     gene            17890..18522
                     /gene="yrbL"
                     /locus_tag="IRB70_002556"
     CDS             17890..18522
                     /gene="yrbL"
                     /locus_tag="IRB70_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoP regulatory network protein YrbL"
                     /protein_id="HBC0632459.1"
                     /translation="MIRLSEQSPLGTGRHRKCYAHPEDAQRCIKIVYHRGDGGDKEIR
                     RELKYYAHLGRRLKDWSGIPRYHGTVETDCGTGYVYDVIADFDGKPSITLTEFAEQCR
                     YEEDIAQLRQILKQLKRYLQDNRIVTMSLKPQNILCHRISESEVIPVVCDNIGESTLI
                     PLATWSKWCCLRKQERLWKRFIAQPALTIALQKDLQPRESKTLTLTSREA"
     gene            complement(18519..19247)
                     /gene="mtgA"
                     /locus_tag="IRB70_002557"
     CDS             complement(18519..19247)
                     /gene="mtgA"
                     /locus_tag="IRB70_002557"
                     /EC_number="2.4.1.129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="monofunctional biosynthetic peptidoglycan
                     transglycosylase"
                     /protein_id="HBC0632460.1"
                     /translation="MSKSRLTVFSFVRRFLLRLMVVLAVFWGGGIALFSVAPVPFSAV
                     MVERQVSAWLHGNFRYVAHSDWVSMDQISPWMGLAVIAAEDQTFPEHWGFDVASIEKA
                     LAHNERNENRIRGASTISQQTAKNLFLWDGRSWVRKGLEAGLTLGIETVWSKKRILTV
                     YLNIAEFGDGVFGVEAAAQRYFHKPASKLTRSEAALLAAVLPNPLRFKVSAPSGYVRS
                     RQAWILRQMYQLGGESFMQQHQLD"
     gene            complement(19244..19897)
                     /gene="elbB"
                     /locus_tag="IRB70_002558"
     CDS             complement(19244..19897)
                     /gene="elbB"
                     /locus_tag="IRB70_002558"
                     /EC_number="4.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312115.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenoid biosynthesis glyoxalase ElbB"
                     /protein_id="HBC0632461.1"
                     /translation="MKKIGVILSGCGVYDGSEIHEAVLTLLAISRSGAQAVCFAPDKQ
                     QVDVINHLTGEAMTETRNVLIEAARITRGEIRPLAQADAAELDALIVPGGFGAAKNLS
                     NFASLGRECTVDRELKALAQAMHQAGKPLGFMCIAPAMLPKIFDFPLRLTIGTDIDTA
                     EVLEEMGAEHVPCPVDDIVVDEDNKIVTTPAYMLAQNIAEAASGIDKLVSRVLVLAE"
     gene            complement(20127..22463)
                     /gene="arcB"
                     /locus_tag="IRB70_002559"
     CDS             complement(20127..22463)
                     /gene="arcB"
                     /locus_tag="IRB70_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobic respiration two-component sensor
                     histidine kinase ArcB"
                     /protein_id="HBC0632462.1"
                     /translation="MKQIRLLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTM
                     VLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDL
                     SLNVQLKDNIAQLNQEIAVREKAEAELQETFGQLKIEIKEREETQIQLEQQSSFLRSF
                     LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPADVYSPEAAAKVIETDEK
                     VFRHNVSLTYEQWLDYPDGRKACFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDAL
                     ERASRDKTTFISTISHELRTPLNGIVGLSRILLDTELTAEQEKYLKTIHVSAVTLGNI
                     FNDIIDMDKMERRKVQLDNQPVDFTSFLADLENLSALQAQQKGLRFNLEPTLPLPHQV
                     ITDGTRLRQILWNLISNAVKFTQQGQVTVRVRYDEGDMLHFEVEDSGIGIPQDELDKI
                     FAMYYQVKDSHGGKPATGTGIGLAVSRRLAKNMGGDITVTSEQGKGSTFTLTIHAPSV
                     AEEVDDAFDEDDMPLPALNVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKAALEMFK
                     PGEYDLVLLDIQLPDMTGLDISRELTKRYPREDLPPLVALTANVLKDKQEYLNAGMDD
                     VLSKPLSVPALTAMIKKFWDTQDDEESTVTTEENSKSEALLDIPMLEQYLELVGPKLI
                     TDGLAVFEKMMPGYVSVLESNLTAQDKKGIVEEGHKIKGAAGSVGLRHLQQLGQQIQS
                     PDLPAWEDNVGEWIEEMKEEWRHDVEVLKAWVAKATKK"
     gene            complement(22559..23488)
                     /locus_tag="IRB70_002560"
     CDS             complement(22559..23488)
                     /locus_tag="IRB70_002560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562163.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBC0632463.1"
                     /translation="MQLQKLVNMFGGDLTRRYGQKVHKLTLHGGFSCPNRDGTIGRGG
                     CTFCNVASFADEAQQHRSIAEQLAHQANLVNRAKRYLAYFQAYTSTFAEVQVLRSMYQ
                     QAVSQANIVGLCVGTRPDCVPDAVLDLLCEYKDQGYEVWLELGLQTAHDKTLHRINRG
                     HDFACYQRTTQLARERGLKVCSHLIVGLPGEGQAECLQTLERVVETGVDGIKLHPLHI
                     VKGSIMAKAWEAGRLNGIELEDYTLTAGEMIRHTPPEVIYHRISASARRPTLLAPLWC
                     ENRWTGMVELDRYLNEHGVQGSALGRPWLPPTA"
     gene            24162..28622
                     /gene="gltB"
                     /locus_tag="IRB70_002561"
     CDS             24162..28622
                     /gene="gltB"
                     /locus_tag="IRB70_002561"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase large subunit"
                     /protein_id="HBC0632464.1"
                     /translation="MLYDKSLERDNCGFGLIAHIEGEPSHKVVRTAIHALARMQHRGA
                     ILADGKTGDGCGLLLQKPDRFFRIVAQERGWRLAKNYAVGMLFLNKDPELAAAARRIV
                     EEELQRETLSIVGWRDVPTNEGVLGEIALSSLPRIEQIFVNAPAGWRPRDMERRLFIA
                     RRRIEKRLEADKDFYVCSLSNLVNIYKGLCMPADLPRFYLDLADLRLESAICLFHQRF
                     STNTVPRWPLAQPFRYLAHNGEINTITGNRQWARARTYKFQTPLIPDLHDAAPFVNET
                     GSDSSSMDNMLELLLAGGMDIIRAMRLLVPPAWQNNPDMDPELRAFFDFNSMHMEPWD
                     GPAGIVMSDGRFAACNLDRNGLRPARYVITKDKLITCASEVGIWDYQPDEVVEKGRVG
                     PGELMVIDTRSGRILHSAETDDDLKSRHPYKEWMEKNVRRLVPFEDLPDEEVGSRELD
                     DDTLASYQKQFNYSAEELDSVIRVLGENGQEAVGSMGDDTPFAVLSSQPRIIYDYFRQ
                     QFAQVTNPPIDPLREAHVMSLATSIGREMNVFCEAEGQAHRLSFKSPILLYSDFKQLT
                     TMKEDHYRADTLDITFDVTKTTLEATVKELCDKAEKMVRSGTVLLVLSDRNIAKDRLP
                     VPAPMAVGAIQTRLVEQSLRCDANIIVETASARDPHHFAVLLGFGATAIYPYLAYETL
                     GRLVDTHAIAKDYRTVMLNYRNGINKGLYKIMSKMGISTIASYRCSKLFEAVGLHDDV
                     VGLCFQGAVSRIGGASFEDFQQDLLNLSKRAWLARKPISQGGLLKYVHGGEYHAYNPD
                     VVRTLQQAVQSGEYSDYQEYAKLVNERPATTLRDLLAITPGENAVNIADVEPASELFK
                     RFDTAAMSIGALSPEAHEALAEAMNSIGGNSNSGEGGEDPARYGTNKVSRIKQVASGR
                     FGVTPAYLVNADVIQIKVAQGAKPGEGGQLPGDKVTPYIAKLRYSVPGVTLISPPPHH
                     DIYSIEDLAQLIFDLKQVNPKAMISVKLVSEPGVGTIATGVAKAYADLITIAGYDGGT
                     GASPLSSVKYAGCPWELGLVETQQALVANGLRHKIRLQVDGGLKTGVDIIKAAILGAE
                     SFGFGTGPMVALGCKYLRICHLNNCATGVATQDDKLRKNHYHGLPFKVTNYFEFIARE
                     TRELMAQLGVTRLVDLIGRTDLLKELDGFTAKQQKLALSKLLETAEPHAGKALYCTEN
                     NPPFDNGLLNAQLLQQAKPFVDERQSKTFWFDIRNTDRSVGASLSGYIAQTHGDQGLA
                     ADPIKAYFNGTAGQSFGVWNAGGVELYLTGDANDYVGKGMAGGLIAIRPPVGSAFRSH
                     EASIIGNTCLYGATGGRLYAAGRAGERFGVRNSGAITVVEGIGDNGCEYMTGGIVCIL
                     GKTGVNFGAGMTGGFAYVLDESGDFRKRVNPELVEVLSVDDLAIHEEHLRGLITEHVQ
                     HTGSQRGEEILANWSTFATKFALVKPKSSDVKALLGHRSRSAAELRVQAQ"
     gene            28635..30053
                     /gene="gltD"
                     /locus_tag="IRB70_002562"
     CDS             28635..30053
                     /gene="gltD"
                     /locus_tag="IRB70_002562"
                     /EC_number="1.4.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001540975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate synthase subunit GltD"
                     /protein_id="HBC0632465.1"
                     /translation="MSQNVYQFIDLQRVDPPKKPLKIRKIEFVEIYEPFSEGQAKAQA
                     DRCLSCGNPYCEWKCPVHNYIPNWLKLANEGRIFEAAELSHQTNTLPEVCGRVCPQDR
                     LCEGSCTLNDEFGAVTIGNIERYINDKAFEMGWRPDMSGVKQTGKKVAIIGAGPAGLA
                     CADVLTRNGVKAVVFDRHPEIGGLLTFGIPAFKLEKEVMARRREIFTGMGIEFKLNTE
                     VGRDVQLDDLLSDYDAVFLGVGTYQSMRGGLENEDADGVYAALPFLIANTKQLMGFGE
                     TNDEPFVSMEGKRVVVLGGGDTAMDCVRTSVRQGAKHVTCAYRRDEENMPGSRREVKN
                     AREEGVEFKFNVQPLGIEVNGNGKVSGVKMVRTEMGEPDAKGRRRAEIVAGSEHIVPA
                     DAVIMAFGFRPHSMEWLAKHSVELDSQGRIIAPEGNDNAFQTSNPKIFAGGDIVRGSD
                     LVVTAIAEGRKAADGIMNWLEV"
     gene            30237..31349
                     /locus_tag="IRB70_002563"
     CDS             30237..31349
                     /locus_tag="IRB70_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1016 family protein"
                     /protein_id="HBC0632466.1"
                     /translation="MESLSEGTTAGYQQIHDGIIHLVDSARTETVRSVNALMTATYWE
                     IGRQIVEFEQGGETRAAYGAQLIKRLSKDLSLRYKRGFSTRNLWQFKNFYICFQRIEI
                     VQTLSAQFTPTIRQTLSGESCHLAQLAKSFPLPWSTYVRLLSVKNADARSFYEKETLR
                     CGWSARQLERQIATQFYERTLLSHDKSAMLQQHAPAETHILPQRAIRDPFVLEFLELK
                     DEYSESDFEEALINHLMDFMLELGDDFAFVSRQRRLRIDDNWFRVDLLFFHRRLRCLL
                     IVDLKVGKFSYSDAGQMNMYLNYAKEHWTLPDENPPIGLILCAEKGVGEAHYALAGLP
                     NTVLASEYKMQLPDEKRLADELVRTQAVLEEGYRRR"
     gene            complement(31409..31873)
                     /locus_tag="IRB70_002564"
     CDS             complement(31409..31873)
                     /locus_tag="IRB70_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBC0632467.1"
                     /translation="MMMGEVQSLPSAGLHPALQDALTLALAARPQEKAPGRYELQGDN
                     IFMNVMTFNTQSPVEKKAELHEQYIDIQLLLNGEERILFGMAGTARQCEEFHHEDDYQ
                     LCSAIENEQTIILKPGMFAVFMPGEPHKPGCVVGEPGEIKKVVVKVKADLMA"
     gene            complement(31870..32745)
                     /gene="nanK"
                     /locus_tag="IRB70_002565"
     CDS             complement(31870..32745)
                     /gene="nanK"
                     /locus_tag="IRB70_002565"
                     /EC_number="2.7.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312122.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine kinase"
                     /protein_id="HBC0632468.1"
                     /translation="MTTLAIDIGGTKLAAALIGADGQIRDRRELPTPASQTPEALRDA
                     LSALVSPLQVHAQRVAIASTGIIRDGSLLALNPHNLGGLLHFPLVKTLEQLTDLPTIA
                     INDAQAAAWAEYQALEGDITEMVFITVSTGVGGGVVSGGKLLTGPGGLAGHIGHTLAD
                     PHGPVCGCGRTGCVEAIASGRGIAAAAQGELAGANAKTIFTHAGQGDEQAQQLIHRSA
                     HVLARLIADIKATTDCQCVVVGGSVGLAEGYLALVETYLAQEPAAFHVDLLAAHYRHD
                     AGLLGAALLAQGEKL"
     gene            complement(32742..33431)
                     /locus_tag="IRB70_002566"
     CDS             complement(32742..33431)
                     /locus_tag="IRB70_002566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBC0632469.1"
                     /translation="MSLLAQLDQKIAANGGLIVSCQPVPDSPLDKPEIVAAMALAAEQ
                     AGAVAIRIEGVANLQATRAVVSVPIIGIVKRDLEDSPVRITAYIEDVDALAQAGADII
                     AIDGTDRPRPVPVETLLARIHHHGLLAMTDCSTPEDGLACQKLGAEIIGTTLSGYTTP
                     ETPEEPDLALVKTLSDAGCRVIAEGRYNTPAQAADAMRHGAWAVTVGSAITRLEHICQ
                     WYNTAMKKAVL"
     gene            complement(33479..34969)
                     /gene="nanT"
                     /locus_tag="IRB70_002567"
     CDS             complement(33479..34969)
                     /gene="nanT"
                     /locus_tag="IRB70_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312124.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialic acid transporter NanT"
                     /protein_id="HBC0632470.1"
                     /translation="MSTTTQNIPWYRHLNRAQWRAFSAAWLGYLLDGFDFVLIALVLT
                     EVQGEFGLTTVQAASLISAAFISRWFGGLMLGAMGDRYGRRLAMVTSIVLFSAGTLAC
                     GFAPGYITMFIARLVIGMGMAGEYGSSATYVIESWPKHLRNKASGFLISGFSVGAVVA
                     AQVYSLVVPVWGWRALFFIGILPIIFALWLRKNIPEAEDWKEKHGGKAPVRTMVDILY
                     RGEHRIANIVMTLAAATALWFCFAGNLQNAAIVAVLGLLCAAIFISFMVQSTGKRWPT
                     GVMLMVVVLFAFLYSWPIQALLPTYLKTDLAYDPHTVANVLFFSGFGAAVGCCVGGFL
                     GDWLGTRKAYVCSLLASQLLIIPVFAIGGANVWVLGLLLFFQQMLGQGIAGILPKLIG
                     GYFDTDQRAAGLGFTYNVGALGGALAPIIGALIAQRLDLGTALASLSFSLTFVVILLI
                     GLDMPSRVQRWLRPEALRTHDAIDGKPFSGAVPFGSAKNDLVKTKS"
     gene            complement(35078..35971)
                     /gene="nanA"
                     /locus_tag="IRB70_002568"
     CDS             complement(35078..35971)
                     /gene="nanA"
                     /locus_tag="IRB70_002568"
                     /EC_number="4.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate lyase"
                     /protein_id="HBC0632471.1"
                     /translation="MATNLRGVMAALLTPFDQQQALDKASLRRLVQFNIQQGIDGLYV
                     GGSTGEAFVQSLSEREQVLEIVAEEAKGKIKLIAHVGCVSTAESQQLAASAKRYGFDA
                     VSAVTPFYYPFSFEEHCDHYRAIIDSADGLPMVVYNIPALSGVKLTLDQINTLVTLPG
                     VGALKQTSGDLYQMEQIRREHPDLVLYNGYDEIFASGLLAGADGGIGSTYNIMGWRYQ
                     GIVKALKEGDIQTAQKLQTECNKVIDLLIKTGVFRGLKTVLHYMDVVSVPLCRKPFGP
                     VDEKYLPELKALAQQLMQERG"
     gene            complement(36093..36884)
                     /gene="nanR"
                     /locus_tag="IRB70_002569"
     CDS             complement(36093..36884)
                     /gene="nanR"
                     /locus_tag="IRB70_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312126.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator NanR"
                     /protein_id="HBC0632472.1"
                     /translation="MGLMNAFDSQTEDSSPVIGRNLRSRPLARKKLSEMVEEELEQMI
                     RRREFGEGEQLPSERELMAFFNVGRPSVREALAALKRKGLVQINNGERARVSRPSADT
                     IIGELSGMAKDFLSHPGGIAHFEQLRLFFESSLVRYAAEHATDEQIDLLAKALEINSQ
                     SLDNNAAFIRSDVDFHRVLAEIPGNPIFMAIHVALLDWLIAARPTVADQALHEHNNVS
                     YQQHIAIVDAIRRHDPDEADRALQSHLNSVSATWHAFGQTTNKKK"
BASE COUNT         9131 a        10051 c         9319 g         8545 t
ORIGIN      
        1 atggccgggg ttttgctgat taacgcttgt aaatgaactc aacgccttct tcgtcgtctt
       61 cgtcccagtc gtcatcccag tcctcatcat cctcttcagc aatctcttca agctgctggc
      121 gatgataatc atcccacatg aattcgactt tctctggctg tttcgcttct tcagcctgca
      181 cgaccgggtt ttcaatgata aaggtcatca catcccagca gagatctttc acgcccagtc
      241 cactcgccgc agagatcaga taatatttat cttcccagcc cagcgcctca gcgatcgctt
      301 tcgctttctc ttcggcttct gccttatcca gcagatcgat cttgttgaag actaaccaac
      361 gcggtttcgc cgccagatcc tggctgtatt tttccagctc gctgataata atacgcgcgt
      421 tttcaaccgg atcggtgccg tcaatcggat cgatatcgat gaggtgcaac aggacgcggc
      481 aacgttccag gtgcttcagg aagcgaatgc ccagacctgc gccttccgca gcgccttcaa
      541 tcagtcctgg aatatcggca acaacgaagc tcttttcgtt gtccattcgt accacaccca
      601 gacttggcac cagagtggta aacggataat ccgccacttt cggtttagcc gccgataccg
      661 cacgaataaa ggtcgattta cccgcgtttg gcatccccaa cataccgacg tcagccagca
      721 gcatcagctc cagcagcagc tcacgtttat cgcccggcgt accgttagtt ttctgccgtg
      781 gtgtacggtt aactgacgat ttgaaacggg tattgcccag accgtgccag ccgcccttag
      841 caaccagcag acgctgaccg tgtttggtca tatcgcccat ggtttcacca gtaccctggt
      901 cgattacacg cgtacctacc ggcactttaa ttgtgacgtc tttaccgcgc ttaccggtac
      961 agtcgcggct tgcgccattc tgaccgcgct ctgcacggaa agatttttca aaacgataat
     1021 cgataagcgt gttcaggttc tcgtcggctt ccatccatac gtcaccacca tcaccgccgt
     1081 cgccgccatc cgggccgcct ttcggaatat acttttcgcg gcggaagctc acgcaaccat
     1141 taccgccatc acctgcaacg accagaatcg atgcttcatc aacaaacttc attttattct
     1201 ccgtaaatca ttcgcctgcg cggggttgcg ataccaccgt tgtatgctta cgtaatccgc
     1261 cccaaatacg atgaccaatg gcggaataca tcgcgcccgc aaccacgaca aacgcaccga
     1321 gataacctaa aaggtttaac atcggtctgg cgaagaaatc gggccaggcc agtgacaaaa
     1381 gatctgaaaa aaacagcgta aacagtgggg tgagcgtgat gatcgcgctc acctgcgctg
     1441 cctgccagcg agccatcgct tccgccaggg cgccatatcc taccaaggta ttcagtccgc
     1501 aaaaaattaa acatgcgagc tgccagtggc taagctgcgc tatcactcca ggctttgcca
     1561 gagggaagag cgcaattgta cataaagtgt acagtaaaaa caggatctgc ggtgaggcca
     1621 gccgacgcaa taaaaccttt tgcgccacgc cataactcac ccacaccgtc gccgcaccga
     1681 ccccaaagat tactccccag gtgtaatcgg tgagctttgt aaatatctcg accagactgg
     1741 tgttaaaaaa catcaccagg ccgctcagga gcatcaatgc ccctacaacc tgagtgctgc
     1801 gcattttctc tttcaggata aatacgctgg caaccatcat gccaactggc gagagttgcc
     1861 caatcacctg cgaagcggtc ggactcaggt attgcaagga tgagctgaac aggatgaagt
     1921 tcccaaacag cccggcggtc gccactgcca acaaaatcaa ccagcgtggc ttacgaaaca
     1981 cgcgtaatgg cggcaacctc ttcttcaccg caagaatggc accaaggcca atactcgcca
     2041 tcaagaaacg gtaaaacacg attgtcggag gttccatcac ctccagcacc tgcttcattg
     2101 cgattggcaa cgccccccag caaattgctg tggtgagcgc caaaagaatg ccaatgcctg
     2161 cctgctgctt cataccgtat tccctgcaaa gcgcatttgc ggattaacgt cgcaccatgc
     2221 gcatttttac cggttatcga atgtaaaaag ccccgcaacg tgttgcgggg ctttcatccg
     2281 ttaccgggac gcgaaaaact tattcagctt cgatgctgat aaatttacgg tttttcgggc
     2341 ctttaacttc gaatttcact ttaccgtctg ctttagcaaa cagagtgtgg tcacgaccgc
     2401 aacctacgtt agcgccagcg tggaatttgg taccacgttg acgaacgatg atgctacccg
     2461 ccagaacgga ttcgccaccg aaacgcttaa cgcccaggcg tttagcttct gaatcgcgac
     2521 cgttacgtgt ggagccgcca gcctttttat gtgccatttg aaatctctcc tcaggtctta
     2581 ggcgctgatg ccagtaattt tcacatcagt gaaccactga cgatggccct gctgcttacg
     2641 atagtgttta cgacgacgaa acttaacgat tttaactttc tcgccacgac cgtgagcaac
     2701 aacttcagct ttgattacgc cgccatcaac gaaaggaacg ccgattttga cttcttcacc
     2761 gtttgcgatc atcagcactt cagcgaactc aacagtttcg ccagttgcga tgtccagctt
     2821 ttccaggcga acggtctgac cttcgcttac tcggtgttgt ttaccaccac tttggaaaac
     2881 cgcgtacata taaaactccg cttccgcgca caccttttca atgattcaga gtgcgctata
     2941 aatattcaca atagggcgcg aatattacgc aaaacgcacg cctttgacaa gtgctacagt
     3001 caatacacga agaaaaaaaa cacaacttgt acggtaacgt ttatctgtgc cattttttca
     3061 gtacaatcac cctatattcc taaccataaa ccctaagttg cctttgttca cagtaaggta
     3121 atcggggcga aaagcccggc ttttgcgatg aatttagaaa aaatcaatga gttaaccgcg
     3181 caagatatgg cgggtgttaa tgcggcaatc cttgagcagc ttaattccga cgtccaactg
     3241 atcaatcagt taggctatta catcgtcagc ggcggcggta aacgtattcg tccgatgatt
     3301 gctgtactgg ctgcacgagc tgttggctat gagggaaatg cgcatgtcac cattgctgcc
     3361 ctgatcgagt ttatccacac ggcgactctg ctgcacgacg acgttgtgga tgaatcagat
     3421 atgcgcaggg gtaaagctac cgccaacgcc gcatttggca atgccgccag cgtgctggta
     3481 ggcgatttta tttatacccg cgcgttccag atgatgacca gcctcggctc gctcaaagtg
     3541 ctggaagtca tgtcagaagc cgtaaacgtc atcgcagaag gtgaagttct gcaactgatg
     3601 aacgttaacg atccggacat cactgaagaa aactacatgc gcgttatcta tagcaaaacc
     3661 gcgcgtctgt ttgaggctgc cgcgcagtgt tccgggattc tggctggctg tacgccggag
     3721 gaggagaaag gcctgcagga ttatgggcgc tatctcggca ctgctttcca gttgatcgac
     3781 gatttactcg attacaatgc cgatggcgaa cagttaggta aaaacgtcgg cgacgatctg
     3841 aacgaaggta aaccgacgct gccgctgctg catgcaatgc atcatggcac accagaacag
     3901 gcacagatga ttcgtaccgc catcgaacag ggtaacggtc gccatcttct ggaaccggtt
     3961 ctggaagcaa tgaacgcttg tggatctctt gaatggacgc gtcagcgtgc cgaggaagaa
     4021 gcagacaaag ccatcgcagc gttacaggtg ctcccggaca ccccttggcg agaagcactc
     4081 atcggcctcg cgcacatcgc tgttcaacgc gatcgttaat cccctccccc tcatcccgcg
     4141 cagcgcgcgg gatgattcca gtaaattcca taaaaacact tattcagctc tataaaacct
     4201 gaaaaatagg gctgtacatc tttatatatt ctgaatattc acactcttta caggaacttt
     4261 ttagagcaat aggccatcag gagtatagtg atgctcgaca gaagaagtgt tctgaatgaa
     4321 agcgactaac ttaaggagtg aggaaagatg gaaagtaatt tcattgactg gcatcccgct
     4381 gacatcattg cgggtttgcg caagaaggga acgtcaatgg cggcggaatc tcgcagaaat
     4441 ggtttgagtt cctcaacgct ggcgaacgca ttatcgcgcc cctggccgaa aggagagatg
     4501 attattgcga aagccctggg aactgacccc tggattatct ggccatctcg ctaccatgat
     4561 ccgcagaccc atgagtttat cgacagaacg cagttgatgc gtagctacac taaaccgaaa
     4621 aaatgagtgg tctggcggta gccccgcgaa cggggctgcc agctctcaga caattactcg
     4681 cctttcacac gctcaatatt tgcacctaaa gcgcgcagtt tgtcttcaat gcgttcgtag
     4741 ccacgatcga tgtgataaat acgatcaact accgtcgtcc cttccgcaat acagccagcc
     4801 agcaccaggc ttgctgatgc acgcagatcg gttgccataa cctgtgcgcc agaaagtttt
     4861 tcaacaccgt gacaaataac ggtattgctt tcgatttcgg catgcgcgcc catacggctc
     4921 agctctggca catgcataaa gcggttttca aagaccgttt cggtgatgaa cccggtccct
     4981 tctgccacca ggttcaacag cgtgaactgg gcctgcatat cggtcgggaa tgccggatgc
     5041 ggcgcggtac gtacgttaac agccttcgga cgtttgccat gcatatccag gctaatccag
     5101 tcttcgccga cttcgatgtc cgctccagcg tcacgcagtt tcgccagcac ggcgtccaga
     5161 gtatctggct gcgcgttacg gcagataatt ttgccgcgag agatcgccgc cgccaccagg
     5221 aaagtaccgg tttcgatacg atccggcagc acgcgataga caccgccgcc taaacgttcc
     5281 acaccttcaa tgacgatacg atcggtgccc tgaccgctaa ttttcgcacc cagcgtaatc
     5341 aggaagttcg cggtatcgac gatttccggt tcacgcgctg cgttttcaat aatcgtggtg
     5401 ccttcggcca gggttgcagc acacatgatg gtcaccgttg cgccaacgct gactttatcc
     5461 atcacgatat gtgcgccttt caaacgacca tcgacggaag ctttaacgta accttcttcc
     5521 agtttgatgg tcgcgcctaa ttgttcgaga ccagaaatgt gtagatcaac cggacgtgca
     5581 ccaatcgtac aaccgccagg cagtgaaact tgcccctgac caaagcgcgc taccagcggc
     5641 cccagcgccc agatagaagc acgcatggtt ttaaccagat cgtaaggtgc gcagaataca
     5701 ttaacgtcgc gggcatcaat atgcacagaa ccattacgtt ctactttcgc acccagctgg
     5761 cttagcagct tcattgatgt atcgacgtct tttagtttcg ggacgttctg gatctctacc
     5821 ggttcttccg ccagtagtgc ggcaaaaagg ataggcagag cagcattttt agcgccggaa
     5881 attgtgactt cgccctggag cttcgttggc ccctgaacac gaaatttatc catttagttt
     5941 gttctcagtt aacaattcat atccgctacc ggcgaatcgc ccatagctca aaagccgttc
     6001 agtttgcgat cgcgcgccca ctccgcaggg gtatacgctt tgatcgacac agcatgaatg
     6061 cggttatccg caatatattc catcagcggg ccatagaccg tctgctgttt tttaacccga
     6121 ctcatgccgt caaacaactc acccacggca ataacctgaa agtggctgcc atcgccggaa
     6181 acgtggactt cctggaggga gagagcgttc atcaacacgc tctgaatttc attattttcc
     6241 atgggatctt caatcatcag ttaataaatc agcgaaacat cttagagcaa agttgcgctg
     6301 gcataaataa gcaaaaagcc tcgctgataa atcagacaag gctcgacttg caggcaggtt
     6361 tgccggacag gcggttaacg ccatatccgg cctgaaaaaa tttaacgagg cagaacatca
     6421 gcaggcaaat tatacaattt cgccagggta tacactttgt cgtttacccc ctgaagcgtc
     6481 acattgttgc cctgcttttt cgccagatcg ataagatgga gcagcagtgc cagtccaccc
     6541 gtatccacgc gagacacacg gctaagatcg atgctggtaa tccccttcac cgcttcctca
     6601 cgtatttccc aaagcggtag cagaacgtcc tgatccagct ctccggataa cgccagcgtg
     6661 tcacccgtct gcatccagct cagtgactcg ctcattattt tttctcttcc agagtgattt
     6721 tctgttgaga aatcgatttc agttgtgcag tcaggccgtc gatacctttg gtacgcagca
     6781 gcgttcccca ctcgttttgt ttggtggtga tcatactgac gccttcagca atcatgtcgt
     6841 aagcctgcca gttgcccgtc tgggagtttt tacgccattg gaagtccaga cgcaccggcg
     6901 ggcggccatt tgggtcaata atggtaacgc gaataggcac aatggtttta tcgcccagcg
     6961 gctgttctgg cgcaatctga taggtttgac cgtgatacat cgccagcgcc tgaccgtaag
     7021 cctgcttcag gtactcacgg aaagcggcaa agtaagcatc acgttgagca ggggtcgcac
     7081 tcttgtaata ctggcccagc accagcgcac cggcgtattt cacctgtacg tatggcagca
     7141 gttcctgatc gacaatggta cgcagataat ccgggttggc ccgaatttgc ggttgctcat
     7201 tcttcaggcg atcgaacgtt ttctgcgccg cctcgtccat cagcttatac ggattggtct
     7261 ggtctgccgc ggttgccgca ctcagcggtg caatcaccag caaagcgacc atcattaaac
     7321 gtttaaacat gcgtcggttc tcctgaaatt atttcgttgt acccacaggt tcagtggttt
     7381 cattattacc tggcgcagca gctggcgcat cgccactatt cttattgtca tcgcctttac
     7441 taccgtaaag gaactgacca atgagatctt ccagcaccat cgcagacttg gtgtcctgaa
     7501 ttgtatcgcc atccttcagg atagcagtcc ccagttccgg gtcttcaaaa ccgacgttta
     7561 atgccagata ttgttccccc agcaggccgg aagtacgaat gctcagcgaa ctggtatcag
     7621 gaatgtggtt ataacgttgt tcaatttcca gcgttacgcg cggcagatag gttttcgggt
     7681 ccagcgtaat atccgccacc cggcccacaa caacgccacc aatgctgacc ggagagcgcg
     7741 ctttcaggcc gccaatgtta tcgaacgtcg cataaagcgt ataggtcggt tcagtacgta
     7801 tggacgtcac gttcgccgcc ttcaggcaaa caaacagcgc cgccagtagt gctgctaata
     7861 aaaagatacc cacccaaatt tcattttttt tcgtttgcat gaactcaatt cccaaacatc
     7921 aatgcggtca gcacaaaatc cagccccaga acagccagag acgagtggac aacggtgcga
     7981 gtggttgccc ggctaatccc ggcagacgtc gggatggcgt cgtagccgtt aaacaacgaa
     8041 atccacgtca ccgtgatggc gaacaccacg ctcttaatca gacagttgac cagatccata
     8101 cgccagtcga cggcattttg cattgccgac cagaagaacc cgctatcaat gcctttccaa
     8161 ctgacgccga ccagagatcc gccccagatc cccacggcga cgaaaataac cgtcaacagt
     8221 ggtaatgaaa taaccccagc ccagaaacgg ggagaaataa cccgacgcaa cggatccacc
     8281 gccatcatct ccatactgga gagttgctct gtagcgcgca tcaggccgat ttctgcggtt
     8341 agcgccgaac cagcacgccc ggcaaacaac aacgcggcaa ccaccggccc cagttcacgc
     8401 agtagcgata acgccaccag catacccaga ctggtttccg cactataagt ggtcagaacc
     8461 agataacctt gcagccccaa caccattccg atgaacacgc cagaaactac aataatcagc
     8521 atcgacagga cgccgacatt atagagctgg cgcaccagca gcggcgcatg tttgcgaaat
     8581 tccggtttgc cgaccagcgc attgaataac attaacccgg cccgcccgaa cgttctcagg
     8641 gttttaatcc ctttatgtcc gagcgacgcc agcgcattta acagcatgag tggcttaact
     8701 ccctggtaaa agatcagcgt gataatcgcc ggcaggatag cggaacggaa caggcccgtc
     8761 agctatcccg tccagaaact gacgtacgcg cggatcagga ttcgcctgca acgcctgggc
     8821 actgccatga gcgacaattt ttttgtccgc caggatccag gcgtgatccg caatacttaa
     8881 cacttccggc acatcgtgag aaaccaccac acaagtcacg cccagcgcgc tgttcagctc
     8941 agaaatcagc ttcaccagta cgcccatggt gatgggatct tgcccaacaa agggttcatc
     9001 aaacatgatg agatccggct ccagcgcaat cgcacgcgcc agagctgcac gccgcgccat
     9061 cccaccggaa agttcagaag gcataagttt agccgctcca cgcagcccca cggcctccag
     9121 cttcatcatc accgtactat gcaacaatgg cgcgggaagt tgggtatgtt cgcgcagtgg
     9181 ataggcgacg ttgtcaaata cgttcatatc agtgaacaac gccccggact gaaataacat
     9241 gctcatccgt ttgcgcactg tatacaggcg cgaacgagac atcgccggaa tattctcacc
     9301 atcgaaaagg atctcaccat gatctggtgc gatttgcccg ccaatcagac ggagtagcgt
     9361 cgttttaccg atgcccgatg gccccatgat cgccgtgatc ttccctcgcg gcacggtcag
     9421 ggaaatatta tcgaagatgc agcgatttcc acgcgtaaaa ctgacatcgc gcatatcgac
     9481 taaattcgcc acagactgct ccataattca cccttcgtct tgcgttgatt ttctaagcat
     9541 ggcgctcaat ttaaccttga acccaacata tttacagaat attacccgcc gtggttagcg
     9601 aaagctggca tttgttttac tttttagccg cataaagtca aaattaagaa tccgttacgg
     9661 ctttctgaaa atcttcagcg gaccggcgag tatacctgaa gaaaggacgt tagatgcttt
     9721 tagctacggc actgttaatt gttggtttac ttttggtcgt ttacagtgcc gaccgcctgg
     9781 tttttgccgc gtctattctt tgccgaacct ttggcatccc gccgctaatc atcggcatga
     9841 cggtggtcag tattggtaca tcgttaccag aaatcatcgt ctcgcttgcc gcgtctttgc
     9901 acgaacaacg cgatttagcc gttggtacag ccctcggctc aaacattatc aatatattgc
     9961 tgatcctcgg tcttgctgcg ctggttcgtc cttttaccgt ccattctgat gttctacgcc
    10021 gtgaattacc cttaatgttg ttggtcagcg tggtggccgg ttccgtactc tatgacggac
    10081 aacttagtcg cagcgatggt atctttctcc tctttctggc tgtgctatgg ctgctgttca
    10141 ttgttaaact tgcacgtcag gctgaacgtc aggggactga cagcctgacc agagagcagc
    10201 ttgcagagtt gccgcgtgac ggtggattgc ccgtcgcgtt tttatggctc ggcattgcgc
    10261 ttatcatcat gccagtggcc acgcggatgg tggttgataa cgccacggtg ctggcgaatt
    10321 actttgccat cagcgagttg acgatgggtc tgacggcaat tgctatcgga accagcctgc
    10381 cggaactggc aaccgcaata gcgggggttc gcaaaggtga aaacgacatt gctgtcggaa
    10441 atatcattgg cgcaaacatt tttaatattg tcatcgtgtt gggtttaccc gcgctgataa
    10501 cgccaggaaa gattgatcca ctggcgtaca gtcgtgacta cagcgtgatg ttgctggtga
    10561 gcattatttt tgcgttgctg tgctggcggc gctccccgca atcgggccgt ggtgtagggg
    10621 tattattaac tggcggattt atcgtatggc tggcgatgtt gtactggtta tcgccaatac
    10681 tcgttgaata actggaaacg cattatgtcg cacgtagagt tacaaccggg ttttgacttt
    10741 cagcaagcag gtaaagaagt cctggcgatt gaacgtgaat gcctggcgga gcttgatcaa
    10801 tacatcaatc agaatttcac gcttgcctgt gaaaagatgt tctggtgtaa agggaaagtt
    10861 gtcgtcatgg ggatggggaa atcggggcac atcgggcgca aaatggcggc aacgtttgcc
    10921 agcactggta caccttcatt tttcgtccat cctggtgaag ccgcgcatgg tgatttaggc
    10981 atggtcaccc cacaggatgt ggtgattgct atctctaact caggtgaatc cagcgaaatc
    11041 acggccttaa ttccagtgct taagcgtctt cacgtaccgt taatctgcat caccggtcgc
    11101 ccggagagca gcatggcgcg cgccgcagat gtgcatctgt gtgttaaagt agcgaaagaa
    11161 gcctgtccgt tagggctggc accgaccagc agcaccaccg ccacgctggt tatgggcgat
    11221 gccctcgctg tcgcgctgtt aaaagcacgc ggctttactg ctgaagattt tgcgctctca
    11281 cacccaggcg gcgcactggg tcgtaaactt ctgctgcgcg taaacgatat tatgcatacg
    11341 ggcgatgaga tcccgcatgt taagaaaacg gccagtctgc gtgacgcatt gctggaagtt
    11401 acccgcaaaa atcttggtat gactgtcatt tgcgatgaca atatgatgat tgaaggcatc
    11461 tttaccgacg gtgatttacg ccgtgtcttc gatatgggcg tggatgttcg tcagttaagt
    11521 attgccgatg tgatgacgcc ggggggaata cgtgtgcgcc ctggcattct ggccgttgag
    11581 gcactgaact taatgcagtc ccgccatatc acctccgtga tggttgccga tggcgaccat
    11641 ttactcggtg tgttacatat gcatgattta ctgcgtgcag gcgtagtgta aagattcaag
    11701 gataaacaac aatgagcaaa gcaggtgcgt cgcttgcgac ctgttacggc cctgtcagcg
    11761 ccgacgttat ggcaaaagca gagaacattc gtctgctgat cctcgatgtc gatggcgtac
    11821 tgtcagatgg cctgatttat atgggcaata atggcgaaga gctgaaagcg ttcaatgttc
    11881 gtgacggtta tggcattcgt tgtgcgctca cctctgatat tgaagtcgct atcattaccg
    11941 ggcgaaaggc taaactggta gaagatcgtt gtgccacatt ggggatcact cacttgtatc
    12001 aggggcagtc aaacaaactg atcgccttta gcgatctgct ggaaaaactg gcgattgccc
    12061 cggaaaatgt ggcttatgtc ggcgatgatc tcatcgactg gccggtaatg gaaaaagtgg
    12121 ggttaagcgt cgccgtggcc gatgcgcatc cattgttgat cccgcgcgcc gattacgtga
    12181 cgcgcattgc tggcggtcgt ggcgcagtgc gagaagtttg cgacttatta ctcctggcgc
    12241 agggcaaact ggatgaagcc aaagggcaat cgatatgagt aaagccagac gttgggttat
    12301 cattgtgcta tcactggcgg ttctggtgat gatcggcatt aatatggccg aaaaagacga
    12361 taccgcccag gtggtcgtca acaacaatga tcccacctat aaaagcgagc atacggacac
    12421 gctcgtctat aacccagaag gggcactaag ctatcgattg attgctcaac atgttgaata
    12481 ttattccgat caggccgttt cgtggtttac gcagccggta cttaccacgt ttgataagga
    12541 taaaatcccg acatggtcag taaaagcaga taaagccaag ctgaccaatg accggatgct
    12601 ctatttatat ggacacgttg aagtcaacgc acttgtgccg gactctcaac ttcgcagaat
    12661 cacgacggat aacgcgcaga tcaatctggt gacgcaggat gttacctctg aagacctcgt
    12721 cacgttatac ggaacaacat ttaactccag cggtctgaaa atgcgcggca acttacgcag
    12781 caagaacgcc gagctgattg aaaaggttag aacatcctat gaaattcaaa acaaacaaac
    12841 tcagccttaa tcttgtgctt gccagctcac ttctggccgc cagcattccg gcatttgctg
    12901 taaccggaga cactgatcag ccgatccaca ttgaatcgga ccagcaatct cttgatatgc
    12961 aaggcaacgt ggttaccttt accggtaatg tcatcgtcac ccagggcacc atcaaaatta
    13021 atgccgacaa agtggtcgtt acccgtccgg gcggcgaaca aggtaaagaa gtgattgacg
    13081 gctacggtaa accggcaacg ttctaccaga tgcaggacaa tggtaaaccc gttgaaggtc
    13141 acgcttccca gatgcactac gaactggcaa aagattttgt cgttctgacg ggtaatgctt
    13201 atctgcagca ggtcgatagc aacattaagg gcgataagat cacttacctg gtgaaagagc
    13261 agaaaatgca ggctttcagc gacaaaggta agcgcgtaac caccgttctg gtgccgtcgc
    13321 agctgcaaga caaaaacaac aaaggccaga ccccggcaca gaagaagggt aattaattcg
    13381 ttatggcaac attaactgca aagaaccttg caaaagccta taaaggccgt cgcgtggtag
    13441 aagacgtcag cctgaccgtc aactccgggg aaattgtcgg tctgctgggg ccaaacggtg
    13501 ccggtaagac caccactttc tacatggttg taggcattgt gccgcgcgat gcgggcaaca
    13561 tcattattga tgatgacgat atcagtctgc tgcctctgca tgcacgcgcg cgccgcggta
    13621 tcggctatct gccacaggaa gcctccattt tccgtcgcct cagcgtttac gataacctga
    13681 tggcggtact gcaaattcgt gacgacttgt ctgctgaaca acgtgaagac cgcgcgaacg
    13741 agctgatgga agagtttcac attgagcacc tgcgtgacag catggggcag tcactctccg
    13801 ggggtgaacg tcgccgtgta gaaattgccc gcgcactggc tgcgaatccg aaatttattc
    13861 tgctcgacga accgtttgcc ggggttgacc cgatctcggt tatcgacatt aaacgcatca
    13921 ttgaacacct gcgcgacagc ggcctgggcg tactgatcac tgaccacaac gtgcgtgaaa
    13981 cactggcggt ttgtgaacgc gcttatatcg tcagtcaggg gcatttgatc gcccacggca
    14041 cgcctacaga aatcttacaa gacgaacacg ttaagcgtgt ataccttggg gaagacttca
    14101 gactctgata gggtagaagt ttgcgacgtt ttagcaggag agtacgattc tgaacatgaa
    14161 gcaaggtttg caactcaggc ttagccaaca actggcgatg acgccacagc tccaacaggc
    14221 aattcgtctg ttgcagttgt cgacgctgga acttcagcag gagctacagc aggcgctgga
    14281 gagtaatccg ctgcttgagc aaatcgacac tcatgaagaa atcgacaccc gcgaaacgca
    14341 agacagtgaa acactggaca ccgccgacgc gctcgaacaa aaagagatgc cggaagagct
    14401 gccgctcgat gccagttggg acaccattta caccgctggt acaccatccg gcaccagcgg
    14461 tgactacatt gacgacgagc tgccggtcta tcagggcgaa acgacgcaga ccttgcagga
    14521 ttacctgatg tggcaggtcg agttgacacc gttttccgac actgaccgcg ctattgctac
    14581 ctctatcgtc gatgccgttg atgacactgg ttatctgact gtcccgctgg aagatattct
    14641 cgaaagtatg ggcgatgaag agattgacat cgacgaagtt gaagccgtcc ttaagcggat
    14701 ccaacggttt gatccggtcg gtgtggcggc aaaagatctg cgtgactgcc tgctgatcca
    14761 actctcccaa ttcgataaaa ccacgccgtg gctggaagag gccagactga ttattagcga
    14821 tcatctcgat ctgttagcca atcacgactt ccgcacttta atgcgcgtca cgcgtctgaa
    14881 agaagatgtg ctgaaagaag ccgtcaatct gatccagtcg ctcgatccgc gccccgggca
    14941 gtcgatccag actggcgaac ctgagtatgt cattccagat gtgctggtgc gtaagcataa
    15001 cggtcactgg acggtagaac tcaacagtga cagcattccg cgtctgcaaa tcaaccagca
    15061 ctacgcctcg atgtgcaata acgcgcgcaa cgatggtgac agccagttta tccgcagcaa
    15121 tctgcaggat gccaaatggt tgatcaagag tctggaaagc cgtaacgata cgctactgcg
    15181 cgtgagtcgc tgtatcgttg aacagcagca agccttcttt gagcaaggtg aagaatatat
    15241 gaaaccgatg gtactggccg atatcgccca ggctgtcgaa atgcatgaat cgacgatatc
    15301 tcgcgtgacc acgcaaaaat acctgcatag tccacgaggc atttttgaac tgaagtattt
    15361 cttttccagt cacgtcaata ccgagggcgg cggcgaagct tcctccacgg cgattcgtgc
    15421 gctggtgaag aaattaatcg cggcggaaaa cccagcgaaa ccgttgagcg acagcaagtt
    15481 aacctctttg ctgtcggaac aaggtatcat ggtggcacgc cgcactgttg cgaagtaccg
    15541 agagtcttta tccattccgc cgtcaaacca gcgtaaacag ctcgtttgac ccaaccgata
    15601 aggaagacac tatgcagctc aacattaccg gaaataacgt cgagatcacc gaggcactgc
    15661 gcgaatttgt tacagccaaa tttgccaaac ttgagcaata ttttgaccga atcaaccagg
    15721 tctatgttgt tctgaaagtg gagaaagtca cccacacctc agatgcaaca ctgcatgtaa
    15781 acggtggtga aattcatgcc agcgcggaag gtcaggacat gtacgctgcc attgatggct
    15841 taattgataa gctggcacgc cagttgacca aacataaaga taaactgaaa caacactaat
    15901 tgtccgggca attagcatgt gcatggcggc ctgttgtgcg gcacaacggg ccatttgtac
    15961 ggttaatgct ccgagcctgt tccactgttt gagtgggcag gttcttaggt gaaattatga
    16021 caaataatga tacaactcta cagcttagca gtgttcttaa cagggaatgt acgcgaagcc
    16081 gcgtccactg tcagagcaaa aaacgcgccc tggaaatcat cagcgagctg gcggcgaaac
    16141 aacttagcct gccgcctcag gtggtttttg aagctatcct gacgcgggaa aaaatgggca
    16201 gtaccggtat cggcaatggt attgccattc cgcatggcaa actggaagaa gatactctgc
    16261 gtgccgttgg cgttttcgtt cagctcgaaa cgcctatagc tttcgatgcc atcgacaacc
    16321 aaccggtgga tttacttttt gccctgctgg tgccggcaga ccaaactaaa acgcacctgc
    16381 atactctgtc actggtggcg aaacgtctgg cggacaaaac catctgccgc cgtttacgcg
    16441 cagcccagag cgatgaagag ctgtatcaaa tcattacgga taccgaaggt actccggatg
    16501 aagcgtagtt attcggtaat gtctctttta gacgttgtga ggagaaacag tacatggtac
    16561 tgatgatcgt cagcggacgt tcaggttcag gtaaatctgt cgccctgcgt gcgctggaag
    16621 atatgggttt ttactgcgtg gataaccttc ccgtagtgtt gttacccgat ctggctcgaa
    16681 ctctggccga tcgcgagatt tctgccgccg tcagcattga tgttcgtaat atgccggagt
    16741 caccagaaat attcgaacag gcgatgagta acctgcctga cgctttctca ccgcaactac
    16801 tgttcctgga tgccgaccgt aataccttaa ttcgtcgtta cagtgacacg cgccgactgc
    16861 atccgctttc cagcaaaaac ctgtcgctgg aaagtgctat cgacaaagaa agcgatttgc
    16921 tggagcctct gcgttcgcga gcggatctga ttgtcgatac ctcagaaatg tccgttcacg
    16981 agctggctga aatgctgcgt acccgtctgc tgggtaaacg tgaacgcgaa ctgaccatgg
    17041 tctttgagtc ttttggcttc aaacacggta tccctatcga tgcagattac gtctttgacg
    17101 tgcgcttctt gccgaacccg cactgggatc cgaaactgcg tccaatgaca ggtctggata
    17161 agcctgtcgc cgcgttcctc gaccgccaca cagaagtaca caattttatc taccagacgc
    17221 gaagctatct tgagctatgg ttacctatgc tggaaaccaa caaccgtagc tacctgacgg
    17281 tcgccattgg ttgtaccggc gggaagcacc gttcggtgta tattgcagag caactggcag
    17341 actacttccg ctcgcgcggt aaaaacgtcc agtcacgcca tcgtacgctg gaaaaacgca
    17401 aaccatgacc gtcaagcaaa ctgttgaaat cacaaacaag ctgggcatgc atgcccggcc
    17461 tgcaatgaag ctgtttgaat taatgcaagg ttttgacgct gaagtgctgt tacgtaatga
    17521 cgaaggcacc gaggctgaag ccaacagcgt tattgcactg ctgatgctgg attctgccaa
    17581 aggacggcag attgaagttg aagcgaccgg tccgcaggaa gaggaagcac tggccgccgt
    17641 tatcgccctc tttaactctg gttttgatga agattaatct tcatcacttt gacattcaaa
    17701 tcccttcaag ctcccccggc aataagaaaa gcgcgtactg aaatcgttat caatcaacgt
    17761 caattgtaca tttcgtgcgc tttttacttt cagaagaacc ttaagaaaac cttaagaagc
    17821 attgtttaga tttcgtttaa gttaatcgac catactggag atcgtcagaa aatatttcca
    17881 ggagatggca tgattcgctt atctgaacaa agtcccctgg gcaccggaag acatcggaaa
    17941 tgttatgcgc atccggaaga tgcccaacgc tgtatcaaga ttgtctacca tcgtggcgat
    18001 ggtggcgata aagagatccg ccgtgagtta aagtactacg cgcatcttgg tcgtcggtta
    18061 aaagactgga gtggaatacc gcgctatcac ggtaccgttg agacggattg cggaaccggt
    18121 tatgtctacg atgtgattgc agattttgac ggcaaaccct ccattacgct gaccgaattt
    18181 gctgaacaat gccgttacga agaagacatt gcacaactgc gccagatact gaaacagctg
    18241 aagcgttatt tgcaggataa ccgtatcgtg acgatgtcgc tgaagccgca gaatatcctc
    18301 tgtcaccgca tcagtgagtc agaggttatc cccgtcgtct gcgacaacat tggtgaaagc
    18361 acattgattc cactggcgac ctggtcgaag tggtgttgtc tgcgtaagca agagcggtta
    18421 tggaaacgat ttatcgccca accggcgctg actattgccc tgcagaaaga tctgcaacct
    18481 cgtgaaagca aaacgctgac cctcacttcg cgcgaagctt aatccagctg gtgttgttgc
    18541 ataaacgact caccgcctaa ctgatacatc tgccgtaaaa tccacgcctg acggctacgc
    18601 acgtagcccg atggcgcgga gactttgaaa cgaagtggat taggtaatac agctgccagt
    18661 aatgcagctt ccgaccgggt aagcttgctc gcgggtttgt ggaaataacg ttgtgccgca
    18721 gcttcgacgc caaacacacc gtcgccaaat tcggcgatat tcaggtaaac cgtcaggata
    18781 cgctttttgc tccagaccgt ttctatcccc agcgttaatc cagcttccag cccttttcga
    18841 acccagctac gcccatccca taaaaagaga tttttggcag tctgctgaga aatcgttgaa
    18901 gcaccgcgaa tacggttttc attgcgctcg ttgtgcgcca gggctttctc aatggaagcg
    18961 acatcaaagc cccagtgctc aggaaatgtc tgatcttctg cggcaatcac cgccagtccc
    19021 atccacggcg agatttgatc catactgacc cagtcagaat gtgccacgta acgaaaattg
    19081 ccatgcagcc aggcgctgac ctgtcgctcg accattaccg ctgagaaagg aacaggcgca
    19141 acgctaaaca acgcgatgcc cccgccccaa aaaacggcga ggacaaccat taaccgcaaa
    19201 agaaaacggc gaacgaaact aaacaccgtt aagcggcttt tactcattca gccagaacca
    19261 gcacgcggga aaccagctta tcaatgccgc tcgccgcttc tgcaatgttc tgcgccagca
    19321 tatatgccgg ggtggtgaca atcttattgt cttcatcaac cacgatatca tcgacaggac
    19381 acggcacatg ctccgcgccc atctcttcca gcacttctgc ggtatcaata tcagtaccga
    19441 tggtcaaacg cagcgggaaa tcgaaaattt tcggcagcat cgccggggca atacacataa
    19501 aaccaagcgg ttttccggcc tgatgcatcg cttgtgccag cgcctttaat tcacggtcaa
    19561 cggtgcattc gcgaccaaga ctggcaaaat tgcttaaatt cttcgccgcg ccaaaccccc
    19621 ccggcacaat caacgcatcc agttcagcgg catcggcctg ggccagagga cggatttcac
    19681 cgcgcgttat tcgtgccgct tcaatcagca cattgcgcgt ttccgtcatc gcttcgcccg
    19741 ttaaatggtt gataacatca acctgctgct tatccggtgc aaagcagacc gcctgcgcac
    19801 cgctgcgtga aatagctaac aacgtcaaca ccgcttcatg aatttcagaa ccgtcataaa
    19861 cgccgcatcc gctcagaatt acgccaattt tcttcattgt gatcatcctt tcgcaattga
    19921 ctgaaacaca ttaatttttt taataaaaat gctacgcatc acacatttaa ctgattcatg
    19981 taacaaatca tttaagtttt gctatcttaa ctgcgtgcgg cctgaaaaac agtgctgtgc
    20041 ccttgtaact catcataata atttacggcg cagccaagat ttccctggtg ttggcgcagt
    20101 attcgcgcac cccggtctag ccggggtcat tttttagtgg cttttgccac ccacgctttc
    20161 agtacttcta cgtcgtgacg ccactcttct ttcatctctt caatccattc accgacgtta
    20221 tcttcccagg cgggaaggtc aggagactga atttgctgac ccagctgttg cagatggcgt
    20281 aaccccactg accccgccgc acctttaatt ttatgtcctt cctcaacaat gcctttttta
    20341 tcctgcgccg tcagattcga ctccagcacg ctgacatagc ccggcatcat cttctcaaac
    20401 accgctaacc cgtcggtgat cagcttcggt cctacaagtt cgagatactg ttccagcatg
    20461 ggaatatcga gcaatgcttc tgatttactg ttctcttctg tcgtcaccgt actttcctca
    20521 tcatcctggg tatcccagaa tttcttgatc atcgcggtta gcgccggaac agaaagcggc
    20581 ttactcagca catcatccat tccagcattg aggtactctt gtttgtcttt cagcacgtta
    20641 gcggttaagg ccaccagcgg tggtaaatcc tcgcgcggat aacgcttcgt cagttcacga
    20701 gagatatcca gcccggtcat atctggcaac tgaatatcca gcaacaccag gtcgtattcg
    20761 cccggtttaa acatctccag cgccgccttg ccggtcatgg cgacatcaac gctgttacct
    20821 aatttttcca gcacagagcg tgcgacaatc acgttcagtt caatgtcttc caccagcagc
    20881 acattcagcg ccggtaaagg catatcgtct tcatcaaacg catcatcaac ctcttctgct
    20941 accgacggtg cgtggatcgt caacgtaaag gttgaacctt tgccctgttc gctggtaacc
    21001 gtaatatcgc cgcccatatt tttcgccaga cgacgagaaa cggccagacc aataccggtg
    21061 ccggtggcag gtttaccgcc atgactgtct ttcacctggt aatacatggc gaagatttta
    21121 tccagctcat cctgcggaat gccgatacca gagtcttcca cttcaaaatg cagcatatcg
    21181 ccttcatcgt agcgcacgcg cacggtaacc tggccttgct gggtgaattt gacggcgtta
    21241 ctgatgaggt tccacaggat ctgccgtaaa cgcgtcccgt cggtaatgac ctgatgcggt
    21301 aatggcagcg tcggctccag attaaagcgc aatccttttt gttgcgcctg caaggcggag
    21361 agattttcca gatcggcaag gaagctggtg aaatcaaccg gctgattatc aagctggacc
    21421 ttgcgccgtt ccatcttatc catgtcgata atatcgttga agatattccc cagcgtgacg
    21481 gccgaaacat ggatggtttt gaggtatttt tcctgctcgg cggtgagttc ggtatccagc
    21541 agaatgcggc tcaggccgac gataccattc agcggtgtac gcaattcgtg actgatggtg
    21601 gagataaacg tcgttttgtc gcggctggcc cgttcaagcg catcctgata ccgcttacgc
    21661 tcggtaatgt cgcgaccaaa gcccatcaaa ccgtgacgtt tacccacgcg gtcgtagtac
    21721 ggcactttac ggatttcaaa gcaggctttg cgcccgtccg ggtaatccag ccactgttca
    21781 taggtcagtg acacattatg acggaacact ttttcatcgg tttcaatgac ttttgcggcg
    21841 gcttccggtg agtaaacatc agcaggtttc aggtgaacca gttgtttttc gctttttccg
    21901 gtcagcagct ccatcgcgcg gttacagccg gaaaactctt tatcttcgtt acgataaaaa
    21961 accaggtcgg gtgaagcatc aaggaaggaa cgtaagaatg aggattgctg ctcgagctga
    22021 atttgtgtct cttcgcgctc tttgatttca attttcagtt ggccgaaggt ttcctgcagt
    22081 tctgcttccg ctttttcacg aacggcgatt tcctgattta gctgggcaat attatctttt
    22141 aactgaacgt tgaggctcaa atcgcgctcg cgcatctcct ccagtttttg caccagtcgt
    22201 gacagacgtt gccgtgactc ctccagttgc tcgacgacca ccgatagaaa gtagaccgcc
    22261 cacggcgtaa tcagcaaacc aaagaagata gaacgaataa catcaatgct ttcgacctga
    22321 ccatgcagca ccatggttac cgccatttgt accacaatgg caagaacgac gagggccagc
    22381 gccagcaaca ttgagaagcg caccagacct aacttcatca tcaggtcaac ataatactgc
    22441 gccagcagac gaatttgctt cattagggaa ttccttcacg acaacctgcc ccaataatac
    22501 ccaattctga cagttacgtt ataaattgtg tgagaaatgc ggaattcccc tcaatggcct
    22561 acgccgttgg aggtagccac ggacgtccca gcgccgatcc ctgtacgcca tgttcattca
    22621 gataacgatc cagctcgacc attcccgtcc agcgattttc gcaccacaga ggagcaagca
    22681 gcgtcgggcg acgggcgctg gcggaaatgc ggtggtagat cacttccggt ggcgtatggc
    22741 gaatcatttc tccggcagtg agcgtgtaat cttccagttc aataccgttc aaacgccccg
    22801 cttcccaggc tttcgccata atgctgcctt tcacaatatg cagcggatgc agctttatgc
    22861 cgtccacgcc agtttcaacg actcgctcca gcgtttgcaa acattcagcc tgcccttcac
    22921 caggcaggcc gacaattaag tgagaacaca ccttcagccc acgctcacgc gccagctgcg
    22981 tcgtgcgctg ataacaggca aaatcatgac cgcgattgat gcgatgcagc gttttgtcgt
    23041 gggcggtttg tagccccagc tccagccaca cttcgtaacc ctggtcctta tattcgcaaa
    23101 gcagatccag caccgcatcc ggcacgcagt ccgggcgggt accaacacac aaaccgacaa
    23161 tattggcctg gctcaccgcc tgctgataca tagaacgcag cacctgaact tccgcaaagg
    23221 tgctggtata cgcctgaaag taggccagat agcgtttagc gcggttaact aaattcgcct
    23281 ggtgcgccag ttgctcggca atggaacgat gctgctgcgc ttcatcggca aacgaggcca
    23341 cattacagaa tgtgcagcca ccacgcccga tggtaccgtc acggttaggg cagctaaaac
    23401 cgccgtgcag cgtcagctta tgcacctttt gcccataacg acgggtgaga tcaccaccaa
    23461 acatattgac taatttctgt aactgcataa tctgatagac cgcgccttga aaagaggcca
    23521 aagcctgcca tttttagctc aattcggcga tgacctggat caatcgtccc ggcctgcttt
    23581 tatcaactgc ataatcaatc aaaattaccg aaatttcatg cacaatcaca taaatcactt
    23641 ttgcttatct tgtgtcagat ttttttatct ccttatggat tttaggcaaa aacagtagca
    23701 tgaaacgtta ttaccaatta aggcagtata aaatgctggt tttctcgtca gttcaaggca
    23761 ggataagggt taacacgcct ttatgacagt caggaattga ctgtttctct aacgacgccc
    23821 ttttagcctt aaatagaaaa tccactttaa tttcagacaa ttaataaaga attttgcgct
    23881 aaagcacatt tctgtaccaa taagcttgcc atttgacctg tatcagcttt cccgataagt
    23941 tggaaatccg ctggaagctt tctggatgag cagcctgctc atcatattta tgcagtaatt
    24001 gagatcccct cttcaccgta ttaaccgatg cgaaaaggac aacaaggggg cgaatgcgag
    24061 gcgcgcgtat gacacgcaaa ccccgtcgcc acgctcttac tgtgcccgtg cgcagcggtt
    24121 cggaagtggg gttcccgcag agcctggggg aggttcacga tatgttgtac gataaatccc
    24181 ttgagaggga taactgtggt ttcggcctga tcgcccacat agaaggcgaa cctagccaca
    24241 aggtagtgcg tactgcaata cacgcactgg cccgcatgca gcaccgtggc gcgattctcg
    24301 ccgatggtaa aaccggtgac ggttgcggct tgctgttaca aaaaccggat cgcttttttc
    24361 gcatcgttgc gcaggagcgc ggctggcgtt tagcaaaaaa ctacgctgtc gggatgctct
    24421 tcctgaataa agatcctgaa ctcgccgctg ccgcacgccg catcgttgaa gaagagctgc
    24481 aacgcgaaac attgtcgatt gtgggctggc gtgatgtccc cactaacgaa ggcgtgctgg
    24541 gtgaaatcgc cctctcctct ctgccacgca ttgagcaaat ttttgtgaac gccccggcag
    24601 gctggcgtcc acgcgatatg gagcgccgtc tgtttatcgc ccgccgccgc attgaaaagc
    24661 gtctcgaagc cgacaaagac ttctacgtct gtagcctgtc gaatctggtg aacatctata
    24721 aaggtctgtg tatgccggcg gatctgccgc gcttttatct ggatcttgcg gacctgcgtc
    24781 tggaatcggc catttgcctg ttccaccagc gcttttccac taacaccgta ccgcgctggc
    24841 cgctggcaca gccgttccgc tacctcgcgc ataacggtga aatcaacacc atcactggta
    24901 accgccaatg ggcgcgtgcg cgtacctata aattccagac gccgctgatc cctgacctgc
    24961 acgacgccgc gccgttcgtc aacgaaaccg gctctgactc cagttccatg gataacatgc
    25021 tggaactgct gctggcaggc gggatggata tcatccgcgc catgcgtctg ttagtgccac
    25081 ccgcctggca gaacaacccg gatatggacc cggaactgcg tgccttcttt gactttaact
    25141 ccatgcatat ggagccgtgg gatggcccgg caggcatcgt gatgtctgac ggtcgttttg
    25201 ccgcctgtaa cctcgaccgt aacggtctgc gtccggcacg ctatgtcatc accaaagata
    25261 agctcattac ctgcgcctct gaagtcggta tctgggatta tcagcctgac gaagtggtcg
    25321 aaaaaggccg cgtcgggcca ggcgaactga tggtgatcga cacccgcagt gggcgtattc
    25381 tgcactcggc agaaaccgat gacgatctga aaagccgcca tccatataaa gagtggatgg
    25441 agaaaaacgt ccgccgactg gtaccgtttg aagatctgcc cgatgaagaa gtgggtagcc
    25501 gcgaactgga cgacgacacg cttgccagct accagaaaca gtttaactac agcgcggaag
    25561 agctggactc cgtaattcgc gtactgggtg aaaacggtca ggaagccgtc ggttcgatgg
    25621 gcgatgatac cccattcgcc gtgctctcca gtcagccgcg cattatttac gactacttcc
    25681 gccagcagtt tgctcaggta accaacccgc caatcgaccc gctgcgtgaa gcgcatgtta
    25741 tgtcgctcgc caccagcatt ggccgcgaaa tgaacgtctt ctgcgaagct gaaggccagg
    25801 cgcaccgttt aagctttaaa tcgccgattc tgctctattc cgatttcaaa cagctcacga
    25861 cgatgaaaga ggatcactac cgcgcagata cgctggatat cacctttgac gtcactaaaa
    25921 ccacgctcga agcgacggtg aaagagctgt gcgacaaagc cgaaaaaatg gtacgtagcg
    25981 gcaccgtgct gctggtgctc tccgaccgga atatcgctaa agatcgcctg ccggttccgg
    26041 ctccgatggc ggttggcgcg atccagaccc gtctggtcga gcaaagcctg cgttgcgatg
    26101 ccaacatcat cgtcgaaacc gccagcgccc gtgatccgca ccacttcgcc gtgttgctgg
    26161 gtttcggcgc gacggctatt tatccgtacc ttgcctatga aacgctgggc cgtctggtag
    26221 acacccacgc gattgccaaa gattatcgta ccgtgatgct caactatcgt aacggcatca
    26281 acaaaggctt gtacaaaatc atgtccaaaa tgggcatctc caccatcgcc tcttatcgct
    26341 gctcgaaact gtttgaagcg gtcggtctgc acgatgatgt cgtgggcctg tgcttccagg
    26401 gcgcggttag ccgcattggc ggggcgagct ttgaagactt ccagcaggat ctgctgaatc
    26461 tgtcgaaacg tgcctggctg gcgcgtaagc ccatcagcca gggcggcctg ctgaaatacg
    26521 tgcacggtgg cgaataccac gcctacaacc cggacgtggt gcgcacactg caacaggcgg
    26581 tacaaagcgg cgagtacagc gactatcagg aatacgcgaa gctggttaat gagcgtccgg
    26641 caaccacgct gcgcgatctg ctggcaatta cgccgggtga aaacgcagtc aacattgccg
    26701 atgttgaacc ggcaagcgaa ctgtttaaac gcttcgatac cgctgcgatg tctatcggcg
    26761 cgttaagccc ggaagcccac gaggcgctgg ctgaagcgat gaacagcatc ggcggtaact
    26821 cgaactccgg tgaagggggt gaagatccgg cgcgctacgg taccaacaaa gtctcacgca
    26881 tcaagcaggt ggcgtccggt cgcttcggtg ttactccggc gtatctggtc aatgctgacg
    26941 tcattcagat taaagtcgcc cagggcgcga agccgggcga aggcggtcag ttgccgggtg
    27001 ataaagtcac tccttacatt gccaaactgc gctattcggt gcccggagtg acgctgatct
    27061 ccccgccgcc gcaccacgat atctactcta tcgaggactt agcgcagctc attttcgacc
    27121 tcaagcaggt taacccgaaa gcgatgatct ccgtgaagct ggtgtccgaa ccgggcgtcg
    27181 gcaccatcgc gactggcgtg gcgaaagctt atgcggactt gatcaccatc gcaggctatg
    27241 acggcggcac cggcgcaagt ccgctttcat cggtgaaata cgcaggctgt ccgtgggagc
    27301 tggggcttgt tgaaacccaa caggcgctgg ttgccaacgg cttgcgtcac aagatccgtt
    27361 tgcaggttga tggcggcctg aaaaccggcg ttgatatcat caaagcggcg attctcggcg
    27421 cagaaagctt cggcttcggc actggcccga tggtggcgct cggctgtaaa tatctgcgta
    27481 tttgccatct gaacaactgc gcgacgggtg ttgcaactca ggatgacaaa ctgcgtaaga
    27541 atcactatca cggcctgccg ttcaaggtga ctaattactt tgagtttatc gcacgtgaaa
    27601 cccgcgagct gatggcacag ctgggggtaa cgcgtctggt ggatctgatt ggtcgcaccg
    27661 acctgctgaa agagctggac ggtttcaccg ccaaacagca gaaactggcg ctgtcgaagc
    27721 tgctggaaac tgccgagcca catgcaggta aggcactcta ctgcaccgaa aacaacccgc
    27781 cgtttgataa cggcctactg aacgcgcagt tgctgcaaca ggcaaaaccg tttgtcgatg
    27841 aacgccagag caaaaccttc tggttcgata tccgcaacac cgatcgttct gtcggcgcgt
    27901 cgctttcagg ctatatcgcc cagacgcacg gcgatcaggg gctggctgcc gatccgatca
    27961 aagcatactt caacggcacc gcaggccaga gcttcggtgt gtggaacgcg ggcggcgtgg
    28021 aactgtatct gaccggcgat gctaacgact atgtcggtaa aggcatggcg ggcggcttaa
    28081 ttgccattcg tcctccggtt ggctcagcct tccgcagcca tgaagcaagc attatcggca
    28141 acacctgcct gtatggcgcg accggaggtc gtctgtatgc cgcaggccgc gcgggtgaac
    28201 gtttcggcgt acgtaactcc ggtgctatca ccgtggtaga aggcattggc gacaacggct
    28261 gtgaatatat gacgggcggt attgtctgta ttctgggtaa aaccggcgtt aacttcggcg
    28321 cgggcatgac cggcggcttc gcttacgttc tcgatgaaag cggcgatttc cgcaaacgcg
    28381 ttaacccgga actggtcgag gtcttaagcg ttgacgattt ggcgatccat gaagagcatc
    28441 tgcgtggtct tatcaccgag catgtgcagc ataccggttc ccagcgcggt gaagagattc
    28501 tggcgaactg gtcaaccttc gccacgaaat tcgcgctggt taaaccgaag tccagtgatg
    28561 taaaagcact gctgggtcac cgtagtcgta gcgcagcaga gttgcgcgtg caggcgcagt
    28621 aaggggtagc aacaatgagt cagaatgttt atcaatttat cgacctgcag cgcgttgatc
    28681 cgccaaagaa accgctgaag atccgcaaaa ttgagtttgt tgaaatttac gagccgtttt
    28741 ccgaaggcca ggccaaagcg caggctgacc gctgtctgtc gtgcggcaac ccatactgcg
    28801 agtggaaatg cccggtacac aactacatcc cgaactggct gaagctcgcc aacgaggggc
    28861 gtatttttga agcggcagaa ctgtcgcatc agaccaatac cctgccggaa gtgtgcggac
    28921 gtgtctgccc gcaagaccgt ctgtgcgaag gttcctgcac cctgaacgat gagttcggcg
    28981 cagtgaccat cggcaacatt gagcgctata tcaacgataa agcgttcgag atgggctggc
    29041 gtccggatat gtccggcgtg aaacagaccg gtaaaaaagt ggcgattatc ggtgcaggcc
    29101 cggcgggtct ggcgtgtgcg gatgtcctga cgcgcaacgg cgtaaaagcg gttgtcttcg
    29161 accgtcaccc ggaaattggc ggcttgctaa ccttcggtat tccggccttc aagctggaaa
    29221 aagaggtaat ggcgcgccgc cgtgaaatct tcaccggcat gggtattgaa ttcaaactca
    29281 ataccgaagt gggccgcgac gtacagctgg acgatctgct gagtgattac gatgccgtgt
    29341 tccttggcgt cgggacttat cagtcaatgc gcggcgggct ggaaaacgaa gacgccgatg
    29401 gcgtgtacgc agcgctgccg ttcctcatcg ccaacaccaa acagttaatg ggctttggcg
    29461 aaaccaacga cgaaccgttc gtcagcatgg aaggtaaacg cgtggtggtc cttggcggtg
    29521 gcgacactgc gatggactgc gtgcgcacgt ctgtacgcca gggggcaaag cacgttacct
    29581 gtgcctatcg tcgtgatgaa gagaacatgc cgggttcccg ccgcgaagtg aaaaacgcgc
    29641 gggaagaagg tgttgagttc aaattcaacg tccagccgct gggtatagaa gtgaatggca
    29701 acggcaaagt cagcggcgta aaaatggtgc gcacagaaat gggcgaaccg gatgccaaag
    29761 gccgtcgccg cgcagagatc gtggcagggt cagaacatat cgttccggca gatgcggtga
    29821 tcatggcgtt tggtttccgt ccacacagca tggaatggct ggcaaaacac agcgtcgagc
    29881 tggattcgca ggggcgcatt atcgccccgg aaggcaacga caacgctttc cagaccagca
    29941 acccgaaaat ctttgctggc ggcgatatcg tccgtggttc cgatctggtc gttaccgcca
    30001 ttgccgaagg tcgcaaagcg gcagacggca ttatgaactg gctggaagtt taagctctgc
    30061 ctcagcgccg ccttctcaga aaagagtcgg cgctgaaatt ctcctttcgt tctggaaagc
    30121 gcctcgcata atctgaagaa aaccaatgta atacgcacat ctggattgtt accggcagat
    30181 gcccggcgta tagctgattc cattattcaa cactgcgcca tatgaaggga cagataatgg
    30241 aatcgctctc agaaggaacc acagcaggct accagcaaat ccacgacggc attattcatc
    30301 tggtcgatag cgcccggacg gaaacggtac gtagtgttaa cgcgttaatg accgccacat
    30361 actgggaaat tggccgacaa attgtcgaat ttgaacaagg tggcgagacc agggctgcgt
    30421 atggtgcgca gctaatcaag cgactatcaa aggatttaag tctaaggtat aagcgtgggt
    30481 tttccaccag gaatttatgg cagtttaaga atttttatat ttgttttcaa cgaattgaaa
    30541 ttgtgcagac actgtctgca caattcaccc ccacaattcg ccagacacta tctggcgaat
    30601 cttgccattt agcgcaactt gccaaatctt tccccctgcc ctggtccact tacgtccgtt
    30661 tgctttctgt taaaaacgct gacgctcgta gcttttatga gaaagaaaca ctccgctgtg
    30721 gctggtctgc tcgtcagctc gaacggcaaa ttgcgaccca attttatgag cggacactac
    30781 tgtcacatga caaatcagcc atgctgcaac aacacgctcc tgccgagacg catattcttc
    30841 cgcaacgggc gatacgcgat ccctttgtgc tcgaatttct ggaattgaaa gatgaatatt
    30901 cagaatccga ttttgaggag gcgctgatca accacctgat ggatttcatg ctggaacttg
    30961 gggatgattt tgcctttgtt agtcgacagc gaaggttacg cattgatgac aactggtttc
    31021 gtgtcgatct gctgtttttc caccgccgtt tacgctgcct gctaatcgtc gatctaaaag
    31081 tgggcaaatt cagctatagc gatgccggac agatgaatat gtatctcaac tacgccaaag
    31141 agcactggac gctaccggat gaaaatccgc ccatcggtct gattctctgt gcagagaaag
    31201 gagtcggaga agcgcattat gcactggctg gtttacctaa caccgttctg gcgagtgaat
    31261 ataagatgca actacctgat gaaaaacgac tcgcggatga actcgttcga acacaggcgg
    31321 tgttagagga aggctataga cgccgttaat ttcagcggtt tcgaattctc cagacactgt
    31381 ctggagaatc tttaaaacga actaagtttt aagccattaa atcagcctta accttcacca
    31441 caaccttttt aatctcacca ggctcgccaa caacgcatcc tggtttatgc ggttctcctg
    31501 gcataaacac ggcaaacatt cccggtttta agatgatggt ttgctcattc tcaatggcgc
    31561 tgcaaagctg gtaatcatct tcatggtgga actcttcaca ctgacgcgca gtgcctgcca
    31621 tgccaaacag gatccgttcc tcaccgttta ataacagctg gatatcaatg tactgctcgt
    31681 gcaattccgc ttttttctcg acgggcgatt gagtgttaaa cgtcatgaca ttcataaaga
    31741 tattatcgcc ctgtaattcg taacgacccg gcgctttttc ttgcggtctg gcagctaatg
    31801 ccagcgttaa cgcgtcctgt aacgcaggat gtaatccggc agacggtaat gactgtactt
    31861 cacccatcat cataattttt ctccctgggc caacagcgca gccccaagta aacctgcatc
    31921 atggcggtag tgcgccgcca gtaaatcaac atgaaatgcc gctggctcct gcgccagata
    31981 cgtttccacc aacgccagat acccttctgc cagaccaacg ctgccaccga ccactacgca
    32041 ctgacaatca gttgtggctt taatatcagc gatcagcctt gccagcacat gtgcggagcg
    32101 gtgaatcagt tgctgcgcct gctcatcgcc ctgcccagcg tgcgtgaaaa tagttttcgc
    32161 attcgcacca gccaactccc cttgcgccgc cgccgcaatg ccgcgaccag aagcaatcgc
    32221 ctccacgcaa cctgtgcgtc cacagccgca gactggacca tgcggatcgg caagcgtatg
    32281 cccgatgtgc cccgccagac ctccagggcc ggtaagcagt ttgccgccgc tcactacacc
    32341 gccgccgacg ccagtggaaa cggtgataaa caccatctcg gttatatcgc cttccagcgc
    32401 ctgatactcc gcccatgctg cggcctgcgc gtcgttaatg gcaatggtcg gcaaatcggt
    32461 aagctgctcc agtgttttaa ctaacggaaa gtgtagtaat ccaccgagat tatgcggatt
    32521 cagcgccaat aagctgccgt cgcgaataat tccggttgaa gcgatagcaa cccgctgcgc
    32581 atgaacttgc aacggagaga ctaatgcgga taaggcatca cgcaaggctt ctggtgtctg
    32641 gctggctggc gtaggaagtt cacgacgatc gcggatctgc ccatcagcgc caatcagcgc
    32701 ggcggcaagt ttagtaccgc cgatatcaat cgccagtgtg gtcatagcac cgcctttttc
    32761 atcgctgtgt tgtaccactg acaaatgtgt tcaagacgcg taatggcaga accgaccgtc
    32821 accgcccacg cgccgtggcg catcgcatcc gccgcctgag caggcgtgtt gtaacgccct
    32881 tcggcaatca cccgacatcc ggcgtcgctc aacgttttca ccagcgccag atccggctct
    32941 tctggcgttt caggtgtggt atagccagaa agcgtggtgc caataatttc ggctcccagc
    33001 ttttggcaag ccaggccgtc ttccggcgtt gagcagtcgg tcatcgccag taaaccgtga
    33061 tggtgaatac gtgccagcag cgtttcaaca ggcaccggac gcggacgatc ggtgccatca
    33121 atcgcgatga tatccgcgcc tgcctgcgcc agcgcatcga catcttcaat ataggccgtg
    33181 atgcgtaccg gagaatcctc cagatcgcgt ttcacaatcc cgataatcgg cacactcacc
    33241 accgcacgcg tggcttgcag atttgccaca ccttcaatgc gaatggcgac cgcacccgcc
    33301 tgctctgcag ctaatgccat ggcggcgacg atttcgggtt tatcgagcgg gctgtcagga
    33361 accggctggc aggagacaat caggccaccg ttagcagcga ttttttgatc cagttgtgca
    33421 agtaacgaca tacatcttcc cttagcgaaa ggcccggtac agagaccggg caacaggatt
    33481 aacttttggt tttgactaaa tcgtttttgg cgctgccaaa cggcacggca ccgctaaatg
    33541 gtttgccgtc gatagcgtca tgagtacgca atgcttccgg gcgcagccaa cgctgaacgc
    33601 gagaaggcat atccagacca atcagcagga tcaccacaaa cgtcaaactg aacgagagcg
    33661 atgccagcgc agtacccaga tccagacgtt gagcgatcaa cgcgccgatg attggggcca
    33721 gtgcgccgcc caatgcgcca acgttgtagg taaagcccag gcccgctgca cgctggtcgg
    33781 tatcgaaata accgccaatc agtttcggta agatcccggc gatcccttgt ccaagcattt
    33841 gctggaagaa cagtaacaga ccgagcaccc agacgtttgc gccgccaatc gcaaataccg
    33901 gaataatcag cagctgcgag gccagcagac tacaaacgta cgctttgcgg gttcccagcc
    33961 agtcaccgag gaagccaccg acgcagcacc ccaccgccgc gccaaagcca ctaaagaaca
    34021 gcacattggc gacagtatgc gggtcataag ccagatcggt tttcagatat gttggcagca
    34081 gcgcctgaat cggccatgag tagaggaaag caaacaacac gaccaccatc agcattacgc
    34141 ccgttggcca gcgtttgccc gtactctgca ccataaagct gataaagatt gcggcgcata
    34201 acagcccaag aacagcgacg atcgcggcat tttgcaggtt accggcgaag cagaaccaca
    34261 gcgcagtagc cgccgccagt gtcattacga tattggcaat gcgatgttca ccacggtaga
    34321 gaatatccac cattgtgcgt accggtgctt tacccccgtg tttctctttc cagtcttccg
    34381 cttccgggat gtttttacgc agccagagag caaagatgat tggcaaaatg ccgataaaga
    34441 acagcgcacg ccagccccag accggaacca ccagactata gacctgagcg gcaacgacgg
    34501 cccccactga gaagcctgaa atcagaaaac cactggcttt gttacgcaga tgctttggcc
    34561 agctttcaat gacataggtg gcgctggaac cgtattcacc cgccatcccc atgccgatga
    34621 ccagacgagc gataaacatg gtgatgtagc ctggcgcaaa gccgcaggcc agcgtcccgg
    34681 ccgagaagag aacgatgctg gtgaccattg ccagacgacg cccgtagcgg tcacccatag
    34741 cgccgagcat caggccgccg aaccagcgag agataaaggc tgcggagatc agacttgccg
    34801 cctgcaccgt cgtgagcccg aattcaccct gtacttcggt gagtactagg gcgattaaaa
    34861 cgaaatcaaa accgtcaagc agatatccca accaggcagc ggaaaatgcc cgccattgtg
    34921 cgcggttaag atggcgatac cacgggatat tctgggttgt agtactcatt gtgagtctcc
    34981 cgcggtgggc gatgcccaca cgctttggta tgaaaattgt agggtacaga tgcgtttatt
    35041 tcccctcacc cggtaggggc gagcgagggg aaaaaactca cccgcgctct tgcatcaact
    35101 gctgggccag cgccttcagt tctggcagat atttttcatc taccggacca aacggtttgc
    35161 ggcacagcgg cacagaaacg acatccatat aatgcaggac agttttcagg ccgcggaata
    35221 cgcccgtttt gatcagtaaa tcaatgactt tgttgcactc agtttgcagt ttctgcgcgg
    35281 tctggatatc gccttctttc agcgccttaa caatgccctg ataacgccag cccatgatgt
    35341 tgtaggtact accgatacca ccatcagcgc ccgccagaag accagaggcg aagatttcgt
    35401 cgtaaccgtt atagagcacc agatcaggat gttcacgacg gatctgctcc atctgataga
    35461 gatcgccaga agtctgtttc agcgcaccga cgccaggcaa cgtaacaagt gtgttgatct
    35521 gatccagggt aagttttacc ccactcaggg ctggaatgtt gtacaccacc atcggcaaac
    35581 catccgctga atcaataatt gcccgatagt gatcgcagtg ttcttcaaag ctgaaaggat
    35641 agtagaacgg cgtaacggca gagacggcat cgaagccata acgtttagcc gatgccgcaa
    35701 gttgttggct ttcagcagtg ctgacgcaac ctacgtgagc gatgagttta atcttgcctt
    35761 tcgcctcttc ggcgacgatt tccagtacct gttcacgctc ggaaaggctt tgtacaaagg
    35821 cttcgccggt agaaccaccc acgtataaac cgtcgatgcc ctgctgaata ttgaactgaa
    35881 ccaggcgacg cagactcgct ttatccagtg cttgttgttg atcaaaagga gtcaggagtg
    35941 cggccattac gccacgtaaa ttcgttgcca taaatacctc tgaagtgatg cttgtctgat
    36001 aaacgatata cctttatacc tgttatacca gatcaattaa gcaacacccc atacagaaag
    36061 cttataatgc gatctgcttc actaaagtgg cattatttct ttttgttggt ggtctgaccg
    36121 aaggcgtgcc aggtagcaga gacgctgttg agatgcgatt gcaacgcgcg atcggcttca
    36181 tcgggatcgt ggcggcggat cgcgtcaacg atcgcaatat gctgttgata gctaacgttg
    36241 ttatgctcgt gcagagcctg atcagccacg gttggacgtg cggcgatcag ccagtcgagc
    36301 agggcaacgt ggatcgccat gaagattggg ttaccgggga tctccgccag cacgcggtgg
    36361 aaatcaacgt ctgaacgaat gaatgccgcg ttgttatcca gcgactgact gttgatttcc
    36421 agtgcttttg ccagcaaatc gatttgctca tcggtggcgt gttcagccgc atagcgcacc
    36481 aggctggatt caaagaacag acgtaattgt tcgaaatggg caatcccgcc aggatgagaa
    36541 aggaaatctt tcgccatgcc ggaaagctcg ccgatgatgg tgtccgcaga aggacgtgag
    36601 acgcgagcgc gttcgccgtt gtttatctgc accagacctt tgcgttttaa cgctgccagc
    36661 gcttcacgca ccgaaggacg cccgacatta aagaacgcca tcagttcgcg ttcagacggt
    36721 aattgttcac cttcgccaaa ttcacgacgg cggatcatct gttccagctc ttcttccacc
    36781 atttcggaga gttttttacg cgccagcggg cggctgcgta agttgcggcc aattacaggt
    36841 gaagaatctt cggtttgcga atcaaatgcg ttcataaggc ccattctgta aggtcagtgt
    36901 gattaacatc atcagtgaca tcctatcaca ggattgaaag tagggggaaa tggcggggtt
    36961 ttctctttgt gcctcatcat tactatgatt aactgaataa ttaactattg cgaaaaatta
    37021 atgtaacgca gataaaaaca tcccga
//
LOCUS       DADXDL010000046        37037 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.046, whole genome shotgun sequence.
ACCESSION   DADXDL010000046 DADXDL010000000
VERSION     DADXDL010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 37037)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37037)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37037
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.046"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(146..892)
                     /gene="cutC"
                     /locus_tag="IRB70_002570"
     CDS             complement(146..892)
                     /gene="cutC"
                     /locus_tag="IRB70_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBC0632473.1"
                     /translation="MALLEICCYSMECALTVQQNGADRVELCAAPKEGGLTPSLGVLK
                     SVRQRVTIPVHPIIRPRGGDFCYSDGEFAAILEDVRTVRELGFPGLVTGVLDVDGNVD
                     MPRMEKIMAAAGPLAVTFHRAFDMCANPLNTLNNLAELGIARVLTSGQKSDALQGLSK
                     IMELIAHRDAPIIMAGAGVRAENLHHFLDAGVLEVHSSAGAWQASPMRYRNQGLSMSS
                     DAHADEYSRYVVDGAAVAEMKGIIERHQAK"
     gene            complement(906..1472)
                     /locus_tag="IRB70_002571"
     CDS             complement(906..1472)
                     /locus_tag="IRB70_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310612.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBC0632474.1"
                     /translation="MANWQSIDELQDIASDLPRFTHALDELSRRLGLNITPLTADHIS
                     LRCHQNATAERWRRGFEQCGELLSENMINGRPICLFKLHEPVQVAHWQFSIVELPWPG
                     EKRYPHEGWEHIEIVLPGDPETLNARALALLSDEGLSLPGISVKTSSPKGEHERLPNP
                     TLAVTDGKTTIKFHPWSIEEIVASEQSA"
     gene            1688..3421
                     /gene="argS"
                     /locus_tag="IRB70_002572"
     CDS             1688..3421
                     /gene="argS"
                     /locus_tag="IRB70_002572"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBC0632475.1"
                     /translation="MNIQALLSEKVRQAMIAAGAPADCEPQVRQSAKVQFGDYQANGM
                     MAVAKKLGMAPRQLAEQVLTHLDLNGIASKVEIAGPGFINIFLDPAFLAEHVQQALAS
                     DRLGVATPEKQTIVVDYSAPNVAKEMHVGHLRSTIIGDAAVRTLEFLGHKVIRANHVG
                     DWGTQFGMLIAWLEKQQQENTGEMELADLEGFYRDAKKHYDEDEEFAERARNYVVKLQ
                     SGDEYFREMWRKLVDITMTQNQITYDRLNVTLTRDDVMGESLYNPMLPGIVADLKAKG
                     LAVESEGATVVFLDEFKNKEGEPMGVIIQKKDGGYLYTTTDIACAKYRYETLHADRVL
                     YYIDSRQHQHLMQAWAIVRKAGYVPESVPLEHHMFGMMLGKDGKPFKTRAGGTVKLAD
                     LLDEALERARRLVAEKNPDMPADELEKLANAVGIGAVKYADLSKNRTTDYIFDWDNML
                     AFEGNTAPYMQYAYTRVLSVFRKAEIDEEQLAAAPVIIREDREAQLAARLLQFEETLT
                     VVAREGTPHVMCAYLYDLAGLFSGFYEHCPILSAENEEVRNSRLKLAQLTAKTLKLGL
                     DTLGIETVERM"
     gene            3598..4086
                     /locus_tag="IRB70_002573"
     CDS             3598..4086
                     /locus_tag="IRB70_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme inhibitor LprI family protein"
                     /protein_id="HBC0632476.1"
                     /translation="MFKFLVLTLGIISCQVYAEDTLIVNDHDISAIKDCWQKNSDDDS
                     DINVIKSCLRQEYNLVYAQLNKAYGEAYRYIEQVPRTGVKKPDTEQLNLLKKSQRAWL
                     DFRDKECELILSNEDVQDLSDPYSESEWLSCMIIQTNTRTRQLQLYRNSEDFYPSPLT
                     RG"
     gene            complement(4206..4598)
                     /gene="flhe"
                     /locus_tag="IRB70_002574"
     CDS             complement(4206..4598)
                     /gene="flhe"
                     /locus_tag="IRB70_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar protein FlhE"
                     /protein_id="HBC0632477.1"
                     /translation="MRTLLAILLFPLLVQAAGEGMWQASSVGITLNHRGESMSSAPLS
                     TRQPASGLMTLVAWRYQLIGPTPSGLRVRLCSQSRCVELEGQSGTTVAFSGIAAAEPL
                     RFIWEVPGGGRLIPPLKVQRNEVIVNYR"
     gene            complement(4598..6676)
                     /gene="flhA"
                     /locus_tag="IRB70_002575"
     CDS             complement(4598..6676)
                     /gene="flhA"
                     /locus_tag="IRB70_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FlhA"
                     /protein_id="HBC0632478.1"
                     /translation="MSNLAAMLRLPANLKSTQWQILAGPILILLILSMMVLPLPAFIL
                     DLLFTFNIALSIMVLLVAMFTQRTLEFAAFPTILLFTTLLRLALNVASTRIILMEGHT
                     GAAAAGKVVEAFGHFLVGGNFAIGIVVFVILVIINFMVITKGAGRIAEVGARFVLDGM
                     PGKQMAIDADLNAGLIGEDEAKKRRSEVTQEADFYGSMDGASKFVRGDAIAGILIMVI
                     NVVGGLLVGVLQHGMSMGHAAESYTLLTIGDGLVAQIPALVISTAAGVIVTRVSTDQD
                     VGEQMVNQLFSNPSVMLLSAAVLGLLGLVPGMPNLVFLLFTAGLLGLAWWIRGREQKA
                     PAEPKPVKMAENNTVVEATWNDVQLEDSLGMEVGYRLIPMVDFQQDGELLGRIRSIRK
                     KFAQEMGFLPPVVHIRDNMDLQPARYRILMKGVEIGSGDAYPGRWLAINPGIAAGTLP
                     GEATVDPAFGLNAIWIESALKEQAQIQGYTVVEASTVVATHLNHLISQHAAELFGRQE
                     AQQLLDRVAQEMPKLTEDLVPGVVTLTTLHKVLQNLLDEKVPIRDMRTILETLAEHAP
                     IQSDPHELTAVVRVALGRAITQQWFPGKDEVHVIGLDTPLERLLLQALQGGGGLEPGL
                     ADRLLAQTQEALSRQEMLGAPPVLLVNHALRPLLSRFLRRSLPQLVVLSNLELSDNRH
                     IRMTATIGGK"
     gene            complement(6669..7817)
                     /gene="flhB"
                     /locus_tag="IRB70_002576"
     CDS             complement(6669..7817)
                     /gene="flhB"
                     /locus_tag="IRB70_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FlhB"
                     /protein_id="HBC0632479.1"
                     /translation="MSDESDDKTEAPTPHRLEKAREEGQIPRSRELTSLLILLVGVSV
                     IWFGGVSLARRLSGMLSAGLHFDHSIIKDPNLILGQIILLIREAMLALLPLISGVVLV
                     ALISPVMLGGLVFSGKSLQPKFSKLNPLPGIKRMFSAQTGAELLKAILKTILVGSVTG
                     FFLWHHWPQMMRLMAESPITAMGNAMDLVGLCALLVVLGVIPMVGFDVFFQIFSHLKK
                     LRMSRQDIRDEFKQSEGDPHVKGRIRQMQRAAARRRMMADVPKADVIVNNPTHYSVAL
                     QYDENKMSAPKVVAKGAGLVALRIREIGAENNVPTLEAPPLARALYRHAEIGQQIPGQ
                     LYAAVAEVLAWVWQLKRWRLAGGQRPVQPTHLPVPEALDFINEKPTHE"
     gene            complement(8019..8663)
                     /gene="cheZ"
                     /locus_tag="IRB70_002577"
     CDS             complement(8019..8663)
                     /gene="cheZ"
                     /locus_tag="IRB70_002577"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase CheZ"
                     /protein_id="HBC0632480.1"
                     /translation="MMQPSIKPADEHSAGDIIARIGSLTRMLRDSLRELGLDQAIAEA
                     AEAIPDARDRLYYVVQMTAQAAERALNSVEASQPHQDQMEKSAKALTQRWDDWFADPI
                     DLADARELVTDTRQFLADVPAHTSFTNAQLLEIMMAQDFQDLTGQVIKRMMDVIQEIE
                     RQLLMVLLENIPEQESRPKRENQSLLNGPQVDTSKAGVVASQDQVDDLLDSLGF"
     gene            complement(8674..9063)
                     /gene="cheY"
                     /locus_tag="IRB70_002578"
     CDS             complement(8674..9063)
                     /gene="cheY"
                     /locus_tag="IRB70_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002210873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis response regulator CheY"
                     /protein_id="HBC0632481.1"
                     /translation="MADKELKFLVVDDFSTMRRIVRNLLKELGFNNVEEAEDGFDALN
                     KLQAGGYGFVISDWNMPNMDGLELLKTIRADGAMSALPVLMVTAEAKKENIIAAAQAG
                     ASGYVVKPFTAATLEEKLNKIFEKLGM"
     gene            complement(9078..10127)
                     /gene="cheB"
                     /locus_tag="IRB70_002579"
     CDS             complement(9078..10127)
                     /gene="cheB"
                     /locus_tag="IRB70_002579"
                     /EC_number="3.1.1.61"
                     /EC_number="3.5.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000036372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate methylesterase/protein
                     glutamine deamidase"
                     /protein_id="HBC0632482.1"
                     /translation="MSKIRVLSVDDSALMRQIMTEIINSHSDMEMVATAPDPLVARDL
                     IKKFNPDVLTLDVEMPRMDGLDFLEKLMRLRPMPVVMVSSLTGKGSEVTLRALELGAI
                     DFVTKPQLGIREGMLAYSEMIAEKVRTAAKASLAAHKPLSAPTTLKAGPLLSSEKLIA
                     IGASTGGTEAIRQVLQPLPLSSPALLITQHMPPGFTRSFADRLNKLCQIGVKEAEDGE
                     RVLPGHAYIAPGDRHMELARSGANYQIKIHDGPAVNRHRPSVDVLFHSVAKQAGRNAV
                     GVILTGMGNDGAAGMLAMRQAGAWTLAQNEASCVVFGMPREAINMGGVCEVVDLSQVS
                     QQMLAKISAGQAIRI"
     gene            complement(10130..10990)
                     /gene="cheR"
                     /locus_tag="IRB70_002580"
     CDS             complement(10130..10990)
                     /gene="cheR"
                     /locus_tag="IRB70_002580"
                     /EC_number="2.1.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-glutamate O-methyltransferase CheR"
                     /protein_id="HBC0632483.1"
                     /translation="MTSSLPCGQTSLLLQMTERLALSDAHFRRISQLIYQRAGIVLAD
                     HKRDMVYNRLVRHLRSLGLTDFGHYLNLLESNQHSGEWQAFINSLTTNLTAFFREAHH
                     FPLLADHARRRSGEYRVWSAAASTGEEPYSIAMTLADTLGTAPGRWKVFASDIDTEVL
                     EKARSGIYRHEELKNLTPQQLQRYFMRGTGPHEGLVRVRQELANYVDFAPLNLLAKQY
                     TVPGPFDAIFCRNVMIYFDQTTQQEILRRFVPLLKPDGLLFAGHSENFSHLERRFTLR
                     GQTVYALSKD"
     gene            complement(11009..12610)
                     /gene="tap"
                     /locus_tag="IRB70_002581"
     CDS             complement(11009..12610)
                     /gene="tap"
                     /locus_tag="IRB70_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein IV"
                     /protein_id="HBC0632484.1"
                     /translation="MFNRIRISTTLFLILILCGILQIGSNGMSFWAFRDDLQRLNQVE
                     QSNQQRAALAQTRAVMLQASTALNKAGTLTALSYPADDIKTLMTTARASLTQSTTLFK
                     SFMAMTAGNEHVRGLQKETEKSFARWHNDLEHQATWLESNQLSDFLTAPVQGSQNAFD
                     VNFEAWQLEINHVLEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPL
                     AIIGSHFDSIAAGNLARPIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGSQEMHIG
                     IAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQ
                     AGGVQVSTMTHTMQEIATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGF
                     AVVAGEVRNLASRSAQAAKEIKGLIEESVNRVQQGSKLVNNAAATMIDIVSSVTRVND
                     IMGEIASASEEQQRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRV
                     AVFTLEEHEVARYESVQLQIAPVVS"
     gene            complement(12656..14317)
                     /gene="tar"
                     /locus_tag="IRB70_002582"
     CDS             complement(12656..14317)
                     /gene="tar"
                     /locus_tag="IRB70_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyl-accepting chemotaxis protein II"
                     /protein_id="HBC0632485.1"
                     /translation="MINRIRVVTLLVMVLGVFALLQLISGSLFFSSLHHSQKSFVVSN
                     QLREQQGELASTWDLMLQTRINLSRSAVRMMMDSSNQQSNAKVELLDSARKTLAQAAT
                     HYKKFKSMAPLPEMVATSRNIDEKYKNYYTALTELIDYLDYGNTGAYFAQPTQGMQNA
                     MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLT
                     PLAKIIAHIREIAGGNLANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIY
                     AGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDT
                     AQHGGKVVDGVVKTMHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGR
                     GFAVVAGEVRNLASRSAQAAKEIKALIEDSVSRVDTGSVLVESAGETMNNIVNAVTRV
                     TDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQ
                     AVSAFRLAASPLTNKPQTPSRPASEQPPAQPRLRIAEQDPNWETF"
     gene            complement(14462..14965)
                     /gene="cheW"
                     /locus_tag="IRB70_002583"
     CDS             complement(14462..14965)
                     /gene="cheW"
                     /locus_tag="IRB70_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheW"
                     /protein_id="HBC0632486.1"
                     /translation="MTGMTNVTKLASEPSGQEFLVFTLGDEEYGIDILKVQEIRGYDQ
                     VTRIANTPAFIKGVTNLRGVIVPIVDLRIKFSQVDVDYNDNTVVIVLNLGQRVVGIVV
                     DGVSDVLSLTAEQIRPAPEFAVTLSTEYLTGLGALGDRMLILVNIEKLLNSEEMALLD
                     SAASEVA"
     gene            complement(14986..16950)
                     /gene="cheA"
                     /locus_tag="IRB70_002584"
     CDS             complement(14986..16950)
                     /gene="cheA"
                     /locus_tag="IRB70_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chemotaxis protein CheA"
                     /protein_id="HBC0632487.1"
                     /translation="MSMDISDFYQTFFDEADELLADMEQHLLVLQPEAPDAEQLNAIF
                     RAAHSIKGGAGTFGFSVLQETTHLMENLLDEARRGEMQLNTDIINLFLETKDIMQEQL
                     DAYKQSQEPDAASFDYICQALRQLALEAKGETPSAVTRLSVVAKSEPQDEQSRSQSPR
                     RIILSRLKAGEVDLLEEELGHLTTLTDVVKGADSLSAILPGDIAEDDITAVLCFVIEA
                     DQITFETVEVSPKISTPPVLKLAAEQAPTGRVEREKTTRSNESTSIRVAVEKVDQLIN
                     LVGELVITQSMLAQRSSELDPVNHGDLITSMGQLQRNARDLQESVMSIRMMPMEYVFS
                     RYPRLVRDLAGKLGKQVELTLVGSSTELDKSLIERIIDPLTHLVRNSLDHGIELPEKR
                     LAAGKNSVGNLILSAEHQGGNICIEVTDDGAGLNRERILAKAASQGLTVSENMSDDEV
                     AMLIFAPGFSTAEQVTDVSGRGVGMDVVKRNIQEMGGHVEIQSKQGTGTTIRILLPLT
                     LAILDGISVRVADEVFILPLNAVMESLQPREADLHPLAGGERVLEVRGEYLPIVELWK
                     VFNVAGAKTEATQGIAVILQSGGRRYALLVDQLIGQHQVVVKNLESNYRKVPGISAAT
                     ILGDGSVALIVDVSALQAINREQRMANTAA"
     gene            complement(16955..17881)
                     /gene="motB"
                     /locus_tag="IRB70_002585"
     CDS             complement(16955..17881)
                     /gene="motB"
                     /locus_tag="IRB70_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor protein MotB"
                     /protein_id="HBC0632488.1"
                     /translation="MKNQAHPIIVVKRRKAKSHGAAHGSWKIAYADFMTAMMAFFLVM
                     WLISISSPKELIQIAEYFRTPLATAVTGGDRISNSESPIPGGGDDYTQSQGEVNKQPN
                     IEELKKRMEQSRLRKLRGDLDQLIESDPKLRALRPHLKIDLVQEGLRIQIIDSQNRPM
                     FRTGSADVEPYMRDILRAIAPVLNGIPNRISLSGHTDDFPYASGEKGYSNWELSADRA
                     NASRRELMVGGLDSGKVLRVVGMAATMRLSDRGPDDAVNRRISLLVLNKQAEQAILHE
                     NAESQNEPVSALEKPEVAPQVSVPTMPSAEPR"
     gene            complement(17878..18765)
                     /gene="motA"
                     /locus_tag="IRB70_002586"
     CDS             complement(17878..18765)
                     /gene="motA"
                     /locus_tag="IRB70_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor stator protein MotA"
                     /protein_id="HBC0632489.1"
                     /translation="MLILLGYLVVLGTVFGGYLMTGGSLGALYQPAELVIIAGAGIGS
                     FIVGNNGKAIKGTLKALPLLFRRSKYTKAMYMDLLALLYRLMAKSRQMGMFSLERDIE
                     NPRESEIFASYPRILADSVMLDFIVDYLRLIISGHMNTFEIEALMDEEIETHESEAEV
                     PANSLALVGDSLPAFGIVAAVMGVVHALGSADRPAAELGALIAHAMVGTFLGILLAYG
                     FISPLATVLRQKSAETSKMMQCVKVTLLSNLNGYAPPIAVEFGRKTLYSSERPSFIEL
                     EEHVRAVKNPQQQTTTEEA"
     gene            complement(18892..19470)
                     /gene="flhC"
                     /locus_tag="IRB70_002587"
     CDS             complement(18892..19470)
                     /gene="flhC"
                     /locus_tag="IRB70_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhC"
                     /protein_id="HBC0632490.1"
                     /translation="MSEKSIVQEARDIQLAMELITLGARLQMLESETQLSRGRLIKLY
                     KELRGSPPPKGMLPFSTDWFMTWEQNVHASMFCNAWQFLLKTGLCNGVDAVIKAYRLY
                     LEQCPQAEEGPLLALTRAWTLVRFVESGLLQLSSCNCCGGNFITHAHQPVGSFACSLC
                     QPPSRAVKRRKLSQNPADIIPQLLDEQRVQAV"
     gene            complement(19473..19822)
                     /gene="flhD"
                     /locus_tag="IRB70_002588"
                     /pseudo
     CDS             complement(19473..19822)
                     /gene="flhD"
                     /locus_tag="IRB70_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416406.4"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar transcriptional regulator FlhD"
     gene            20603..21031
                     /gene="uspC"
                     /locus_tag="IRB70_002589"
     CDS             20603..21031
                     /gene="uspC"
                     /locus_tag="IRB70_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspC"
                     /protein_id="HBC0632491.1"
                     /translation="MSYSNILVAVAVTPESQQLLAKAVSIARPVKGHISLITLASDPE
                     MYNQLAAPMLEDLRSVMQEETQSFLDKLIQDAGYPVDKTFIAYGELSEHILEVCHKHH
                     FDLVICGNHNHSFFSRASCSAKRVIASSEVDVLLVPLTGD"
     gene            complement(21038..22462)
                     /gene="otsA"
                     /locus_tag="IRB70_002590"
     CDS             complement(21038..22462)
                     /gene="otsA"
                     /locus_tag="IRB70_002590"
                     /EC_number="2.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalose-phosphate synthase"
                     /protein_id="HBC0632492.1"
                     /translation="MSRLVVVSNRIAPPDEHAASAGGLAVGILGALKAAGGLWFGWSG
                     ETGNEDQPLKKVKKGNITWASFNLSEQDLDEYYNQFSNAVLWPAFHYRLDLVQFQRPA
                     WDGYLRVNALLADKLLPLLQDDDIIWIHDYHLLPFAHELRKRGVNNRIGFFLHIPFPT
                     PEIFNALPTYDTLLEQLCDYDLLGFQTENDRLAFLDCLSNLTRVTTRSAKSHTAWGKA
                     FRTEVYPIGIEPKEIAKQAAGPLPPKLAQLKAELKNVQNIFSVERLDYSKGLPERFLA
                     YEALLEKYPQHHGKIRYTQIAPTSRGDVQAYQDIRHQLENEAGRINGKYGQLGWTPLY
                     YLNQHFDRKLLMKIFRYSDVGLVTPLRDGMNLVAKEYVAAQDPANPGVLVLSQFAGAA
                     NELTSALIVNPYDRDEVAAALDRALTMSLAERISRHAEMLDVIVKNDINHWQECFISD
                     LKQIVPRSAESQQRDKVATFPKLA"
     gene            complement(22437..23237)
                     /gene="otsB"
                     /locus_tag="IRB70_002591"
     CDS             complement(22437..23237)
                     /gene="otsB"
                     /locus_tag="IRB70_002591"
                     /EC_number="3.1.3.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose-phosphatase"
                     /protein_id="HBC0632493.1"
                     /translation="MTEPLTETPELSAKYAWFFDLDGTLAEIKPHPDQVVVPDNILQG
                     LQLLATASDGALALISGRSMVELDALAKPYRFPLAGVHGAERRDINGKTHIVHLPDAI
                     AHDISVQLHTVIAQYPGAELEAKGMAFALHYRQAPQHEDALMTLAQRITQIWPQMALQ
                     QGKCVVEIKPRGTSKGEAIAAFMQEAPFIGRTPVFLGDDLTDESGFAVVNRLGGMSVK
                     IGTGATQASWRLAGVPDVWSWLEMITTALQQKRENNRSDDYESFSRSI"
     gene            complement(23404..24390)
                     /gene="araH"
                     /locus_tag="IRB70_002592"
     CDS             complement(23404..24390)
                     /gene="araH"
                     /locus_tag="IRB70_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter permease AraH"
                     /protein_id="HBC0632494.1"
                     /translation="MSSVSTSGSGAPKSSFSFGRIWDQYGMLVVFAVLFIACAIFVPN
                     FATFINMKGLGLAISMSGMVACGMLFCLASGDFDLSVASVIACAGVTTAVVINLTESL
                     WIGVAAGLLLGVLCGLVNGFVIAKLKINALITTLATMQIVRGLAYIISDGKAVGIEDE
                     SFFALGYANWFGLPAPIWLTVACLIIFGLLLNKTTFGRNTLAIGGNEEAARLAGVPVV
                     RTKIIIFVLSGLVSAIAGIILASRMTSGQPMTSIGYELIVISACVLGGVSLKGGIGKI
                     SYVVAGILILGTVENAMNLLNISPFAQYVVRGLILLAAVIFDRYKQKAKRTV"
     gene            complement(24405..25919)
                     /gene="araG"
                     /locus_tag="IRB70_002593"
     CDS             complement(24405..25919)
                     /gene="araG"
                     /locus_tag="IRB70_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter ATP binding protein
                     AraG"
                     /protein_id="HBC0632495.1"
                     /translation="MQQSTPYLSFRGIGKTFPGVKALTDISFDCYAGQVHALMGENGA
                     GKSTLLKILSGNYAPTTGSVVINGQEMSFSDTTAALNAGVAIIYQELHLVPEMTVAEN
                     IYLGQLPHKGGIVNRSLLNYEAGLQLKHLGMDIDPDTPLKYLSIGQWQMVEIAKALAR
                     NAKIIAFDEPTSSLSAREIDNLFRVIRELRKEGRVILYVSHRMEEIFALSDAITVFKD
                     GRYVKTFTDMQQVDHDALVQAMVGRDIGDIYGWQPRSYGEERLRLDAVKAPGVRTPIS
                     LAVRSGEIVGLFGLVGAGRSELMKGMFGGTQITAGQVYIDQQPIDIRKPSHAIAAGMM
                     LCPEDRKAEGIIPVHSVRDNINISARRKHVLGGCVINNGWEENNADHHIRSLNIKTPG
                     AEQLIMNLSGGNQQKAILGRWLSEEMKVILLDEPTRGIDVGAKHEIYNVIYALAAQGV
                     AVLFASSDLPEVLGVADRIVVMREGEIAGELLHEQADERQALSLAMPKVSQAVA"
     gene            complement(25989..26978)
                     /gene="araF"
                     /locus_tag="IRB70_002594"
     CDS             complement(25989..26978)
                     /gene="araF"
                     /locus_tag="IRB70_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arabinose ABC transporter substrate-binding
                     protein AraF"
                     /protein_id="HBC0632496.1"
                     /translation="MHKFTKALAAIGLAAVMSQSAMAENLKLGFLVKQPEEPWFQTEW
                     KFADKAGKDLGFEVIKIAVPDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKAR
                     GYDMKVIAVDDQFVNAKGKPMDTVPLVMMAATKIGERQGQELYKEMQKRGWDVKESAV
                     MAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPE
                     VKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLL
                     PSPDVHGYKSSEMLYNWVAKDVEPPKFTEVTDVVLITRDNFKEELEKKGLGGK"
     gene            27775..28278
                     /locus_tag="IRB70_002595"
     CDS             27775..28278
                     /locus_tag="IRB70_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin-like protein"
                     /protein_id="HBC0632497.1"
                     /translation="MATAGMLLKLNSQMNREFYASNLYLHLSNWCSEQSLNGTATFLR
                     AQAQSNVTQMMRMFNFMKSVGATPIVKAIDVPGEKLNSLEELFQKTMEEYEQRSSTLA
                     QLADEAKELNDDSTVNFLRDLEKEQQHDGLLLQTILDEVRSAKLAGMCPVQTDQHVLN
                     VVSHQLH"
     gene            complement(28357..28608)
                     /locus_tag="IRB70_002596"
     CDS             complement(28357..28608)
                     /locus_tag="IRB70_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416416.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2766 domain-containing protein"
                     /protein_id="HBC0632498.1"
                     /translation="MSQPLNADQELVSDVVACQLVIKQILDVLDVIAPVEVREKMSSQ
                     LKNIDFTNHPAAADPVTMRAIQKAIALIELKFTPQGESH"
     gene            complement(28723..28809)
                     /gene="azuC"
                     /locus_tag="IRB70_002597"
     CDS             complement(28723..28809)
                     /gene="azuC"
                     /locus_tag="IRB70_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein AzuC"
                     /protein_id="HBC0632499.1"
                     /translation="MKLRKILKSMFNNYCKTFKDVPPGNMFR"
     gene            29072..29395
                     /locus_tag="IRB70_002598"
     CDS             29072..29395
                     /locus_tag="IRB70_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecR-like lipofamily protein"
                     /protein_id="HBC0632500.1"
                     /translation="MRLLILTLSLITLAGCTVTRQAHVSEVDAATGIVRLVYDQAFLQ
                     HAHTDRYVSRGIADRACQQEGYTHAVPFGQPVGNCSLFAGSLCLNTEFTLSYQCHHSA
                     FPVFL"
     gene            29566..30063
                     /gene="ftnA"
                     /locus_tag="IRB70_002599"
     CDS             29566..30063
                     /gene="ftnA"
                     /locus_tag="IRB70_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="non-heme ferritin"
                     /protein_id="HBC0632501.1"
                     /translation="MLKPEMIEKLNEQMNLELYSSLLYQQMSAWCSYHTFEGAAAFLR
                     RHAQEEMTHMQRLFDYLTDTGNLPRINTVESPFAEYSSLDELFQETYKHEQLITQKIN
                     ELAHAAMTNQDYPTFNFLQWYVSEQHEEEKLFKSIIDKLSLAGKSGEGLYFIDKELST
                     LDTQN"
     gene            complement(30101..30340)
                     /locus_tag="IRB70_002600"
     CDS             complement(30101..30340)
                     /locus_tag="IRB70_002600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YecH family protein"
                     /protein_id="HBC0632502.1"
                     /translation="MDSIHGHEVLNMMIESGEQYTHASLEAAIKARFGEQARFHTCSA
                     EGMTAGELVAFLAAKGKFIPSKDGFSTDQSKICRH"
     gene            30531..31742
                     /gene="tyrP"
                     /locus_tag="IRB70_002601"
     CDS             30531..31742
                     /gene="tyrP"
                     /locus_tag="IRB70_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine transporter TyrP"
                     /protein_id="HBC0632503.1"
                     /translation="MKNRTLGSVFIVAGTTIGAGMLAMPLAAAGVGFSVTLILLIGLW
                     ALMCYTALLLLEVYQHVPADTGLGTLAKRYLGRYGQWLTGFSMMFLMYALTAAYISGA
                     GELLASSISDWTGISMSATAGVLLFTFVAGGVVCVGTSLVDLFNRFLFSAKIIFLVVM
                     LVLLLPHIHKVNLLTLPLQQGLALSAIPVIFTSFGFHGSVPSIVSYMDGNVRKLRWVF
                     ITGSAIPLVAYIFWQVATLGSIDSTTFMGLLANHAGLNGLLQALREMVASPHVELAVH
                     LFADLALATSFLGVALGLFDYLADLFQRSNTVGGRLQTGAITFLPPLAFALFYPRGFV
                     MALGYAGVALAVLALIIPSLLTWQSRKHNPQAGYRVKGGRPALVVVFLCGIAVIGVQF
                     LIAAGLLPEVG"
     gene            complement(31804..32469)
                     /gene="yecA"
                     /locus_tag="IRB70_002602"
     CDS             complement(31804..32469)
                     /gene="yecA"
                     /locus_tag="IRB70_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YecA"
                     /protein_id="HBC0632504.1"
                     /translation="MKTGPLNESELEWLDDILTKYNTDHAILDVAELDGLLTAVLSSP
                     QEIEPEQWLVAVWGGADYVPRWASEKEMTRFMNLAFQHMADTAERLNEFPEQFEPLFG
                     LREVDGSELTIVEEWCFGYMRGVALSDWSTLPDSLKPALEAIALHGTEENFERVEKMS
                     PEAFEESVDAIRLAALDLHAYWMAHPQEKAVQQPIKAEEKPGRNDPCPCGSGKKFKQC
                     CLH"
     gene            complement(32665..32751)
                     /locus_tag="IRB70_002603"
     tRNA            complement(32665..32751)
                     /locus_tag="IRB70_002603"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32715..32717),aa:Leu,seq:taa)
     gene            complement(32764..32837)
                     /locus_tag="IRB70_002604"
     tRNA            complement(32764..32837)
                     /locus_tag="IRB70_002604"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32803..32805),aa:Cys,seq:gca)
     gene            complement(32892..32967)
                     /locus_tag="IRB70_002605"
     tRNA            complement(32892..32967)
                     /locus_tag="IRB70_002605"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(32932..32934),aa:Gly,seq:gcc)
     gene            complement(33119..33667)
                     /gene="pgsA"
                     /locus_tag="IRB70_002606"
     CDS             complement(33119..33667)
                     /gene="pgsA"
                     /locus_tag="IRB70_002606"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBC0632505.1"
                     /translation="MQFNIPTLLTLFRVILIPFFVLVFYLPVTWSPFAAALIFCVAAV
                     TDWFDGFLARRWNQSTRFGAFLDPVADKVLVAIAMVLVTEHYHSWWVTLPAATMIARE
                     IIISALREWMAELGKRSSVAVSWIGKVKTTAQMVALAWLLWRPNIWVEYAGIALFFVA
                     AVLTLWSMLQYLSAARADLLDQ"
     gene            complement(33724..35556)
                     /gene="uvrC"
                     /locus_tag="IRB70_002607"
     CDS             complement(33724..35556)
                     /gene="uvrC"
                     /locus_tag="IRB70_002607"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310678.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBC0632506.1"
                     /translation="MSDQFDAKAFLKTVTSQPGVYRMYDAGGTVIYVGKAKDLKKRLS
                     SYFRSNLTSRKTEALVAQIQQIDVTVTHTETEALLLEHNYIKLYQPRYNVLLRDDKSY
                     PFIFLSGDTHPRLAMHRGAKHAKGEYFGPFPNGYAVRETLALLQKIFPIRQCENSVYR
                     NRSRPCLQYQIGRCLGPCVEGLVSEEEYAQQVEYVRLFLSGKDDQVLTQLISRMETAS
                     QNLEFEEAARIRDQIQAVRRVTEKQFVSNTGDDLDVIGVAFDAGMACVHVLFIRQGKV
                     LGSRSYFPKVPGGTELSEVVETFVGQFYLQGSQMRTLPGEILLDFNLSDKTLLADSLS
                     ELAGRKINVQTKPRGDRARYLKLARTNAATALTSKLSQQSTVHQRLTALASVLKLPEV
                     KRMECFDISHTMGEQTVASCVVFDANGPLRAEYRRYNITGITPGDDYAAMNQVLRRRY
                     GKAIDDSKIPDVILIDGGKGQLAQAKNVFAELDVSWDKNHPLLLGVAKGADRKAGLET
                     LFFEPEGEGFSLPPDSPALHVIQHIRDESHDHAIGGHRKKRAKVKNTSSLETIEGVGP
                     KRRQMLLKYMGGLQGLRNASVEEIAKVPGISQGLAEKIFWSLKH"
     gene            complement(35553..36209)
                     /gene="uvrY"
                     /locus_tag="IRB70_002608"
     CDS             complement(35553..36209)
                     /gene="uvrY"
                     /locus_tag="IRB70_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UvrY/SirA/GacA family response regulator
                     transcription factor"
                     /protein_id="HBC0632507.1"
                     /translation="MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCR
                     ANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIMLTVHTENPLPAKVMQAGAAGYL
                     SKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
                     ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ
                     "
     gene            36505..36681
                     /locus_tag="IRB70_002609"
     CDS             36505..36681
                     /locus_tag="IRB70_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632508.1"
                     /translation="MIKIFIGHYINAFNSTVDDTLKKQPLLFLAKLMVYSAALTFFTA
                     NFHCNMTRKINEYA"
     gene            36668..36892
                     /locus_tag="IRB70_002610"
     CDS             36668..36892
                     /locus_tag="IRB70_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2594 family protein"
                     /protein_id="HBC0632509.1"
                     /translation="MSTPDFSTAENNQELANEVSCLKAMLTLMLQAIGQADAGRVMLK
                     MEKQLALIEDETQAAVFSKTVKQIKQAYRQ"
     gene            complement(36960..>37037)
                     /locus_tag="IRB70_002611"
     CDS             complement(36960..>37037)
                     /locus_tag="IRB70_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="regulates genes involved in cell division; Derived
                     by automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
                     /protein_id="HBC0632510.1"
                     /translation="KNMQKKINAPNKTQVACYAAATGLI"
BASE COUNT         9120 a         9813 c         8812 g         9292 t
ORIGIN      
        1 gctatgcgca ctgtcacccg ctcaacagat cacggttatc gttcgttttt tatactgctc
       61 agggataaaa aaaggcccct gttgaaattg caggggcctg gtacgagcaa gcatcatatt
      121 gggcgacatg atgcaacggt aaaaatcatt tggcctgatg gcgttcaatg attcctttca
      181 tttcagcaac cgccgccccg tctacgacat aacgcgaata ctcgtccgcg tgtgcatctg
      241 atgacataga caatccttga ttacgataac gcatcggtga ggcttgccac gctcccgcgg
      301 agctatggac ttccagcact ccggcatcga ggaagtggtg caggttttct gcacggactc
      361 ctgctccggc cataatgatt ggagcatcac gatgggcaat aagttccata atttttgata
      421 aaccttgcag tgcgtctgat ttttgccctg atgtcagcac ccgggcaatg cccaattccg
      481 caagattatt gagtgtattt agagggttag cgcacatatc aaaggcgcga tgaaaagtca
      541 ctgccagcgg accggcagca gccattattt tttccattcg tggcatatcg acattcccgt
      601 caacatcgag aacgcccgtc accagtccag gaaaacctaa ttcgcggacc gtgcgcacat
      661 cctcaagaat ggcggcaaac tcaccgtcgc tgtagcaaaa atcaccaccg cgtgggcgaa
      721 ttatcggatg cacagggatc gtcacccgct ggcgcacgga tttcagtaca cccaacgacg
      781 gcgttaagcc cccctctttt ggggctgcgc ataattcaac tctgtctgcg ccgttttgct
      841 gcaccgttag tgcacattcc atgctgtaac agcaaatttc cagtaatgcc atttttactc
      901 cttaattacg ccgactgctc gctggcaacg atctcttcaa tggaccacgg atgaaactta
      961 atagttgttt tgccatcggt gaccgccagc gtcggattcg gtaatcgctc atgctcacct
     1021 tttggcgaac tggttttcac tgagatcccc ggtaggctga gtccttcatc agaaagcaat
     1081 gccagcgcac gggcattcag cgtttctgga tcacccggca gaacgatttc aatatgttcc
     1141 caaccttcgt gtgggtaacg tttttccccg ggccacggta gctccacaat agaaaactgc
     1201 cagtgcgcaa cctgtaccgg ttcatgcaat ttaaacagac aaatcggtct gccattgatc
     1261 atattttctg acaaaagctc gccacactgt tcaaacccgc gacgccagcg ttcagcagtg
     1321 gcgttttgat ggcaacgcaa agaaatgtga tcggcagtca gcggagtgat attcaacccc
     1381 agacggcggg aaagttcatc taatgcgtgg gtaaatcgcg gtaaatccga tgcaatatcc
     1441 tgcagctcgt cgatagattg ccagttcgcc ataatcactc ttcgtctttc agtaaaagcg
     1501 ttaatttacc ctgttgccct gtgccaacca accgctgatt tcacgccgct tctgatgcaa
     1561 tagtgaaaac ggcaatacgc cacgcgcacg ttgctgacga aaacagccat ttgcagtata
     1621 ctcccgccct aatttcttta actggtgcgg gcaatttttg ctcgcttcat caatgtaagg
     1681 tattccggtg aatattcagg ctcttctctc agaaaaagtc cgtcaggcca tgattgcggc
     1741 aggcgcgcct gcggattgcg aaccgcaggt tcgtcagtca gcaaaagttc agttcggcga
     1801 ctatcaggct aacggcatga tggcagttgc taaaaaactg ggtatggcac cgcgacaatt
     1861 agcagagcag gtgctgactc atctggatct taacggtatc gccagcaaag ttgagatcgc
     1921 cggtccaggc tttatcaaca ttttccttga tccggcattc ctggctgaac atgttcagca
     1981 ggcgctggcg tccgatcgtc tcggtgttgc tacgccagaa aaacagacca ttgtggttga
     2041 ctactctgcg ccaaacgtgg cgaaagagat gcacgtcggt cacctgcgct ctaccattat
     2101 tggtgacgca gcagtgcgta ctctggagtt cctcggtcac aaagtgattc gcgcaaacca
     2161 cgtcggcgac tggggcactc agttcggtat gctgattgca tggctggaaa agcagcagca
     2221 ggaaaacacc ggtgaaatgg agctggctga ccttgaaggt ttctaccgcg atgcgaaaaa
     2281 gcattacgac gaagatgaag agtttgccga gcgtgcacgt aactacgtgg taaaactgca
     2341 aagcggtgac gaatatttcc gcgagatgtg gcgcaaactg gtcgacatca ccatgacgca
     2401 gaaccagatc acttacgatc gtctcaacgt gacgctgacc cgtgatgacg tgatgggcga
     2461 aagcctctac aacccaatgc tgccaggaat tgtggcggat ctcaaagcca aaggtctggc
     2521 agtagaaagc gaaggggcga ccgttgtatt ccttgatgag tttaaaaaca aggaaggcga
     2581 accgatgggc gtgatcattc agaagaaaga tggcggctat ctctacacca ccactgatat
     2641 cgcctgtgcg aaatatcgtt atgaaacact gcatgccgat cgcgtgctgt attacatcga
     2701 ctcccgtcag catcaacacc tgatgcaggc atgggcgatc gtccgtaaag caggctatgt
     2761 accggaatcc gtaccgctgg aacaccacat gttcggcatg atgctgggta aagacggcaa
     2821 accgttcaaa acccgcgcgg gtggtacagt gaaactggcc gatctgctgg atgaagccct
     2881 ggaacgtgca cgccgtctgg tggcagaaaa gaacccggat atgccagccg acgagctgga
     2941 aaaactggct aacgcggttg gtattggtgc ggtgaaatat gcggatctct ccaaaaaccg
     3001 caccacggac tacatcttcg actgggacaa catgctggcg tttgagggta ataccgcgcc
     3061 atacatgcag tatgcataca cgcgtgtatt gtccgtgttc cgtaaagcag aaattgacga
     3121 agagcaactg gctgcagctc cggtaatcat ccgtgaagat cgtgaagcgc aactggcagc
     3181 tcgcctgctg cagtttgaag aaaccctcac cgtggttgcc cgtgaaggta cgccgcatgt
     3241 gatgtgtgct tacctgtacg atctggccgg tctgttctct ggcttctacg agcactgccc
     3301 gatcctcagc gcagaaaacg aagaagtgcg taacagccgt ctgaaactgg cacaactgac
     3361 ggcgaagacg ctgaagctgg gtctggatac gctgggtatt gagactgtag agcgtatgta
     3421 atcgattttt cgtgagagtg aagcctgatc agggttacct gatcaggctt ttttattgcc
     3481 atctaaatgt attctgaaaa tggacatgcc atcgttttct cactgttggg taagaagtca
     3541 gaagcgtaat attcggcccc agggaaacga taacggttga atttaaggaa taccgcagtg
     3601 tttaaatttc ttgtattaac attaggcatt atctcttgcc aggtttacgc agaagatacg
     3661 cttatagtaa acgaccatga catttcagcc atcaaagatt gttggcaaaa aaattcagat
     3721 gatgatagtg acattaacgt gatcaaatca tgcctgcgac aagaatacaa tctcgtctat
     3781 gcgcaattaa ataaagccta tggtgaagct tatcgttata tagaacaagt gccacgcaca
     3841 ggtgtaaaaa aacctgatac cgaacaactt aacttgctta aaaaatcaca gcgagcctgg
     3901 ctggatttta gggacaaaga atgtgaatta atcctttcaa atgaggacgt tcaggattta
     3961 agtgaccctt attctgaatc agaatggctc tcatgtatga tcatacagac caatacgcga
     4021 actcgccagt tgcagctata ccgtaactct gaagattttt atccaagccc tttgacaaga
     4081 ggataattca catatttttg gcatgttttg ttgcaaacta ttcctgataa ataattgcaa
     4141 caaaacatcg agcctttttc actgagttat taaacatact cgcgagcgcg taattttttt
     4201 gtccttcagc gataattcac aatcacttca ttacgttgta ctttcagcgg cggaattaac
     4261 cgcccaccgc caggcacttc ccagataaag cgcaacggtt ctgctgccgc tataccggaa
     4321 aaggccacgg tggttccgct ctgcccctct aattcgacac aacgagattg cgaacacaag
     4381 cgaacccgca gtcctgaagg tgtcgggccg ataagctgat aacgccacgc taccagcgtc
     4441 atcaatcctg aagcaggttg tcgcgtagaa agaggcgcag acgacatcga ctcaccgcga
     4501 tgatttagcg taattcctac actacttgcc tgccacatcc cctccccggc ggcttgcacc
     4561 agcagcggaa acaataatat tgctaataag gttctcatta tttgccgcca attgtcgccg
     4621 tcatgcggat atgtcggtta tcagacagtt ccagattcga caggaccact aactgcggca
     4681 agctgcggcg caggaagcga gacaataatg gtcgcagcgc gtggttcacc aacaatactg
     4741 gcggcgcacc cagcatctcc tgacgggata gcgcttcctg agtttgcgcc agtaaacgat
     4801 ccgccagccc tggctccagt cctcccccgc cctgcagcgc ctgtagtaac aaacgttcca
     4861 gcggtgtatc gaggccaata acatggactt catctttgcc aggaaaccac tgctgggtaa
     4921 tcgcccgtcc caacgccacg cgcacgacgg cggttaattc atgtggatcg ctttggatgg
     4981 gcgcatgttc cgccagcgtt tcgagaatgg tgcgcatatc gcgaatcggt actttttcat
     5041 cgaggagatt ttgcagcact ttatgcagtg tggtgagcgt gacgacgcca ggaacgagat
     5101 cttccgtcag ctttggcatc tcctgggcga cgcgatccaa cagctgttgc gcctcctgac
     5161 gaccaaacag ctctgcggca tgctggctaa tgaggtggtt aagatgcgtt gctaccaccg
     5221 tgctggcctc aaccactgtg tacccctgaa tctgcgcctg ttcttttagc gcactttcaa
     5281 tccagatagc attcaggcca aatgccggat cgacggtcgc ctcaccaggt aacgtcccgg
     5341 cagcgattcc agggttaatc gccagccagc gccccggata agcatcacca ctgccaatct
     5401 ccacgccttt catcaaaatg cgatagcggg caggttgcag atccatattg tcgcgaatgt
     5461 gcaccactgg cggcagaaat cccatctcct gggcaaattt cttgcggata ctgcgtatac
     5521 ggcccaacaa ctcaccatcc tgctggaaat cgaccatcgg gatcagtcga taacccactt
     5581 ccattcccag agaatcttcc agttgtacat cgttccacgt cgcttcgaca acggtattat
     5641 tctctgccat ttttaccggt ttgggttcgg caggcgcttt ttgttcgcgt ccgcgtatcc
     5701 accaggccag cccgagcaat ccggcagtga acagcaaaaa taccaggttc ggcattccag
     5761 gcaccaggcc gagtaaaccg agcacggcgg cgcttaacaa cataacgctt gggttactga
     5821 aaagctgatt caccatctgc tcgccaacat cctgatcggt gctgacacgc gtaacgatga
     5881 cccccgcggc ggtagaaatc accagcgccg gaatttgtgc caccagaccg tcgccaatgg
     5941 tcaatagcgt ataactttcc gccgcgtgtc ccatgctcat gccatgttgc agcacgccga
     6001 ccagcaaccc gccgacaacg ttaatgacca tgatgaggat cccggcgatg gcatcgccgc
     6061 gaacaaactt acttgccccg tccattgagc cgtaaaaatc ggcttcctga gtcacttcgg
     6121 agcggcgttt tttcgcctca tcttcaccaa tcaatccggc gttaaggtcg gcgtcaatcg
     6181 ccatctgctt acccggcata ccatcgagaa caaagcgcgc acccacttct gcgatacgcc
     6241 cggcaccttt ggtaatgacc ataaagttga tgatcacgag aatgacaaac accacgatac
     6301 cgatagcgaa attgccacca acgaggaagt gaccgaacgc ttcgaccacc ttccctgccg
     6361 ccgccgcgcc ggtatgccct tccattaaaa tgatacgggt tgaagccacg ttaagtgcca
     6421 gacgcaacag cgtggtaaac aacagaatgg tcggaaacgc agcaaactca agcgtgcgct
     6481 gggtaaacat cgccaccagc aacaccatga tcgacaaggc aatattgaag gtaaacaaca
     6541 ggtcgagtat gaatgcgggc agtggcagca ccatcatcga caagatcaac aggatcaaaa
     6601 tcggtccggc aaggatctgc cattgtgtcg atttcaggtt tgcgggcagg cgcagcatcg
     6661 cggccagatt actcatgggt cggtttctcg ttaataaaat ccagggcttc cggcaccgga
     6721 agatgagtag gttgtacagg gcgctgtcca ccagccagac gccagcgttt cagttgccag
     6781 acccaggcca gcacttccgc caccgcggcg tacagttgac ccgggatttg ttgaccaatc
     6841 tccgcatgtc gatacagcgc tcgcgccagc ggcggcgctt caagcgtcgg gacgttattt
     6901 tcagcgccaa tttcacgaat gcgcagcgcg accagccctg cacctttagc gaccactttc
     6961 ggtgcgctca ttttgttttc gtcatactgc aacgctaccg aatagtgggt cgggttattg
     7021 acaatgacat ccgctttcgg cacatcggcc atcatccgac gccgtgcggc agctcgctgc
     7081 atctgacgga tccgtccttt aacatggggg tcgccttcgc tttgtttgaa ctcatcacga
     7141 atatcctgcc gcgacattcg cagctttttc aggtggctga agatttggaa aaagacgtca
     7201 aatcccacca ttggaatgac accaagcacc accagcagtg cgcatagccc taccaaatcc
     7261 atcgcattac ccatggcggt aatcggagac tcggccatta agcgcatcat ctgcggccag
     7321 tgatgccaga gaaaaaaccc cgtcacgctg ccaaccagga tggttttcaa aattgcttta
     7381 agcaactccg cgccagtctg agccgagaac atccgtttaa tgcccggtag cgggttgagt
     7441 ttggaaaact tcggctgcaa ggatttgccg ctaaatacca gccctcccag catgaccgga
     7501 gaaatgagcg ccaccagtac cacgccgcta atcagtggca gcagcgccag catggcttct
     7561 ctgatcagca gaataatctg cccgaggatc agattcgggt ctttgataat actgtgatca
     7621 aaatgcagcc cagcggagag catgcccgac aatcgacggg ccagcgacac accgccaaac
     7681 cagataacac taacgcccac cagcaaaatc agcagtgagg tcagttcacg ggaacgcggg
     7741 atttgcccct cttcccgcgc tttttctagt cggtgaggtg tgggggcttc tgttttgtcg
     7801 tcgctctcgt cagacacgtc gccaatcctg gaaagagtat taagcgtgaa tgatgccaga
     7861 gcgcaaagcg ttcaatggtt tgagtaaggg gcaaaacagg cgggatttag ggcttttgct
     7921 gccacacatc aagcatagtg tgcgtttgtc ggatgcggcg tcatcgcctt atcagaccgc
     7981 ctgatatgac gtggtcacgc cacatcaggc aatacaaatc aaaatccaag actatccaac
     8041 aaatcgtcca cctgatcctg actggctacc acaccggctt tgctggtatc gacctgaggt
     8101 ccattaagca aactctggtt ttcacgtttt ggacgcgact cctgttccgg gatgttttcc
     8161 aacagcacca tcagcaactg gcgttcgatc tcctgaatga catccatcat ccgcttaatg
     8221 acctgcccgg tgagatcctg aaaatcctgc gccatcatga tttccagcag ttgcgcgtta
     8281 gtaaagctgg tatgcgcggg tacatctgcc agaaattgtc gtgtatctgt taccagttca
     8341 cgggcgtcgg caaggtcaat cggatcggca aaccagtcat cccaacgttg ggttaacgct
     8401 tttgctgatt tctccatttg atcctgatgc ggttgtgacg cctcaacact gttcagcgcc
     8461 cgctccgcag cctgggcggt catctgcaca acatagtaca aacgatcgcg cgcatcgggg
     8521 atggcttccg ccgcttcggc aatggcctga tccagcccca gttcccgcaa actgtcgcgc
     8581 agcatacgcg tcaggctgcc gatgcgcgca atgatatcgc cagctgaatg ctcgtcagca
     8641 ggtttgattg atggttgcat catagtcgca tcctcacatg cccagtttct caaagatttt
     8701 gttgagtttt tcctccagcg tcgcggcggt aaatggcttc accacatagc cactggcccc
     8761 cgcttgcgcc gcagcaatga tgttctcttt cttcgcttct gcagtcacca ttaacactgg
     8821 caatgccgac atcgcgccat ccgcacgaat tgttttcagc aattccaggc catccatatt
     8881 gggcatgttc cagtcggaga taacaaatcc ataaccgcct gcctgcaact tattgagagc
     8941 gtcgaagcca tcttccgctt cctcaacatt attgaatccc agctctttca gcaggttacg
     9001 cactatgcgt cgcatggtgg aaaagtcatc cacaaccaaa aatttaagtt ctttatccgc
     9061 catttcacac tcctgattta aatacgtatc gcctgtccgg cactaatttt tgccagcatt
     9121 tgctggctta cctggctaag atcgaccact tcgcaaacac cacccatatt gatggcctcg
     9181 cgcggcatgc cgaacaccac gcaacttgct tcgttttgcg caagggtcca tgcccccgcc
     9241 tgacgcatcg ccaacattcc cgccgcgccg tcgttgccca taccggtcag gatcacccca
     9301 accgcattac gccccgcctg tttggcgaca gaatggaaca acacatctac cgaaggccga
     9361 tgacggttaa ccgccgggcc atcgtgaatt ttgatttggt aatttgcgcc actacgcgcc
     9421 agctccatat gccgatcgcc cggcgcaata taggcatgcc ccggcaagac acgttctccg
     9481 tcttcggctt ctttaacccc gatctggcaa agcttattaa gtctgtcggc aaaagagcgg
     9541 gtgaaaccgg gcggcatatg ctgggtaatt aacagtgccg ggctggaaag cggcaacggt
     9601 tgcagtacct gacgaattgc ctcagttcca cccgttgaag caccaatcgc aatcagtttt
     9661 tcagaactca acaacggccc cgccttcagc gttgtcggtg ccgacaatgg cttatgtgct
     9721 gcaaggctcg cctttgctgc cgtacgcacc ttttcagcaa tcatttcgct atacgccagc
     9781 ataccttcgc gaatacccag ttgcggtttg gtgacaaaat ctatcgcccc cagctccagc
     9841 gcgcgcagcg tgacttctga ccctttgccg gtcagggaag aaaccatcac aacgggcatt
     9901 ggacgcaaac gcattaattt ttcgaggaaa tccagtccgt ccatccgcgg catttcaaca
     9961 tccagcgtca gcacatcggg attgaatttc ttaatcaagt cacgcgcgac cagcggatca
    10021 ggcgcggtcg ccaccatttc catgtcgcta tggctgttga tgatttctgt catgatctgg
    10081 cgcatcagtg ccgaatcatc gacagataac accctgattt tgctcatcgt taatccttac
    10141 ttagcgcata caccgtctga ccacgcagcg tgaagcggcg ctcaaggtgg ctaaagtttt
    10201 cagagtgacc cgcaaacagc aatccgtcgg gtttaaggag cggaacaaag cggcgcaaaa
    10261 tctcctgctg ggtagtttga tcgaagtaga tcatgacgtt acgacagaag atcgcatcaa
    10321 acggccccgg cacggtgtac tgtttcgcca gtagattcag cggggcaaaa tcaacatagt
    10381 tcgccagctc ctgacgcacg cgtaccagcc cttcatgcgg ccccgtccct cgcatgaaat
    10441 accgttgcag ttgctgcggc gtcaggtttt tcaactcttc atggcgatag ataccgcttc
    10501 tggctttttc cagcacttcg gtgtcgatat cactggcaaa cactttccag cgtccgggcg
    10561 cggtgcccaa tgtgtcagcc agcgtcatcg caatgctgta cggctcttcg ccggtcgaag
    10621 ccgccgcgct ccatacgcga tactcgccag aacggcgacg tgcgtgatcc gcgagcagag
    10681 ggaaatgatg tgcctcacgg aaaaatgccg tcagattcgt ggtcagcgaa ttgataaacg
    10741 cctgccactc accgctgtgc tgattagatt ccagcaagtt cagataatga ccgaaatccg
    10801 tcagtcccag cgaacgcaaa tgacgaacca gtcggttgta aaccatgtcg cgtttatggt
    10861 cagccagaac gatcccggct cgttgataga tcaattgact tatccgccga aaatgcgcgt
    10921 cggaaagcgc caggcgctcg gtcatctgta acaataaaga cgtttgccca cagggcagag
    10981 atgaagtcat agcgccttct caatcacttc aggataccac tggcgcaatt tgtaactgca
    11041 ccgactcata tcgtgctact tcatgttctt caagggtaaa taccgccaca cgcgacgaaa
    11101 gatggtcggc ctgattcgcc agttgttccg ttgccaccgc cgcttcttct accagcgagg
    11161 cgttctgctg agtcacctga tccatctggc tgacagcctg tgcaacctgc tcaatccccc
    11221 gctgttgttc ttccgacgca gaggcaattt ctcccataat gtcgttcacg cgggtcaccg
    11281 aactgacaat atcgatcatg gtcgcggcgg cgttattcac cagtttcgaa ccctgctgga
    11341 cacgattgac tgactcttcg atcagccctt tgatctcttt tgctgcctgc gcgctacggc
    11401 tggcaagatt gcgcacttca cctgccacta ccgcaaaacc acgcccctgc tctccggcgc
    11461 gagccgcttc cactgccgca ttcagggcca gaatattggt ctggaaagca attccgtcga
    11521 taacgctgat aatgtcgcca attttttgcg agctggtggc gatctcctgc atggtgtgag
    11581 tcatggtact gacctgaaca ccgcccgcct gcgccgttgt cgcggcattt tttgccagtt
    11641 ccgacgcctg tcgtgcgtta tcggcgtttt gccctaccgt ggcggttaat tgctccatac
    11701 tggcggccgt ttgtgccagc gatgccgcct gctgttcggt acgacttgag agatcgttat
    11761 tgcctgcgac aatctccgcg ataccaatgt gcatctcctg gcttccctta cgcacatcac
    11821 ttaccgtccc acgcaaagcc tgctgcatgg tcttcagact ggcaaaaatg gcggtgatct
    11881 cattacgacc atataccgca atcggacgcg ccagattacc cgcagcaatg ctgtcaaaat
    11941 ggctaccgat aatggccagt ggttgaacaa tcatcttgcg cgtccaccac agcgcactgc
    12001 tgatgtagat cgccgcaaca ataatcatgc tgataaacac cagtgccgaa atctgatagt
    12061 tacgctggct ttgcgcactg gcggcttcca gcacatggtt gatctccagc tgccaggcct
    12121 caaagttaac gtcaaacgca ttctgtgatc cctgcaccgg cgcagtgagg aaatccgaaa
    12181 gttgattact ttcaagccag gtcgcctgat gttcgagatc gttgtgccag cgggcaaaac
    12241 ttttctccgt ctctttttgc aatcccctga cgtgctcgtt gcccgcagtc atcgccataa
    12301 aacttttaaa cagcgtggtg gattgcgtca gactggcgcg cgccgtcgtc atcaacgttt
    12361 taatgtcatc cgccggatag ctaagtgccg tcagagtgcc cgctttgttc agcgcggtac
    12421 tggcctgtaa cattaccgcc cgagtttgcg ctaatgccgc acgttgctga ttgctctgct
    12481 cgacctgatt cagtcgttgc aaatcgtcgc gaaatgccca aaaagacatg ccgttactgc
    12541 caatctgcaa gatcccgcag agaatcaaaa ttaaaaacag cgtggtcgaa attcgaatac
    12601 gattaaacat caacgctccc catcaggcgg caatgaccgc gttagtaaat actcgtcaaa
    12661 atgtttccca gtttggatct tgttcagcaa ttcgcagtcg tggctgtgcc ggtggttgct
    12721 cactggcagg acgggatggt gtttgcggtt tattggtgag tgggctggct gccagacgga
    12781 acgcggaaac cgcttgcgtt aaacgactcg cctgttcttc cagcgcagcg gcggcggcag
    12841 ctgattcctg caccagcgat gcgttctgtt gcgtgacgcg atccatttcc gaaaccgcca
    12901 atgcgacttg atcgatgcca cggctctgtt catccgatgc cgatgcaatc tcgcccataa
    12961 tgtcagtcac gcgagtgaca gcattgacga tattgttcat tgtttccccg gcgctttcga
    13021 ccagcaccga accggtatca acgcgtgaga cggagtcttc aatgagggct ttgatctctt
    13081 ttgccgcctg ggcgctgcga ctggcaagat tacgcacttc acccgccacc acggcaaaac
    13141 cacggccctg ttcacccgca cgcgcggctt caaccgcggc attcagcgcg aggatattag
    13201 tctggaaggc aataccgtcg ataacgctga taatgtcggc aattttcttc gaactatcgg
    13261 cgatctcatg catcgttttc actacgccat ccaccacttt gccgccgtgc tgggcggtgt
    13321 cggaggcact ttgcgccagt tgcgaggcct ggcgggcgtt atcggcgttt tgcttcactg
    13381 tcgcggtgag ctgctccatg ctggcggcag tttcttccag cgcggatgcc tgctgttcag
    13441 tacgggagga aagatcggtg ttgcccgccg caatttcacg ggtaccggca tagatggcat
    13501 ctgaaccttc gcggacatga gtgacggtgt cagtcaaaga gcgttgcata tgtgaaacgc
    13561 tctgcgccag gtcgcccatt tcactgcgcc cgtcaatggt cagggtattc gccaggttac
    13621 caccggcgat ttcgcgaatg tgagcaataa tttttgccag cggagtaagc aacatacggc
    13681 gaatgccgta ccacgccacc agcagaatca ataccaccac cagcgcgata accgccagtt
    13741 gccactgggc aaatcggtaa tcatctgcgt tgtcagtgac gatatcgcga tacagttttt
    13801 cactgctgag ggcgtactga gcaaacgctt cgcccattgc attttgcatt ccctgggttg
    13861 gctgagcgaa ataagctcca gtattgccat aatctagata atcaatcagt tcagttaacg
    13921 ctgtgtaata gtttttatat ttttcatcaa tattacgact ggtagcgacc atttcaggta
    13981 acggtgccat gcttttgaat tttttataat gcgtcgctgc ctgcgccaat gttttcctgg
    14041 cgctatcgag caattcaact ttggcgttac tttgttgatt ggaggaatcc atcatcatcc
    14101 gtaccgctga acgactcagg ttaatgcgcg tttgcagcat taaatcccag gttgacgcca
    14161 gctcgccctg ctgttcccgt aattgattgg aaaccacaaa gctcttctgg ctatggtgaa
    14221 gggaagaaaa aaacagactg ccggaaataa gctgtaacag tgcgaatacc cccagcacca
    14281 ttaccaacag cgtgactacg cggatacggt taatcataag gcaccttcct gaaaacaagt
    14341 tgatctcgtt atcggcaagg aggggggaaa ctttattgct gatgccaccc gccgcgaaat
    14401 tgaaataaaa aacccgatgc gcagatcatc gggttcattt caattgagga aatcgggaga
    14461 attacgccac ttctgacgcc gcgctatcta acagcgccat ctcttcgctg ttcagcagtt
    14521 tttcgatgtt caccagaatc aacatccggt cgcccagtgc gcccagtcca gtgagatatt
    14581 ctgttgaaag cgtcacggca aattccggtg ccggacgaat ttgctccgcc gtcaatgaaa
    14641 gcacgtctga gacgccgtca accacgatgc cgaccacccg ctgtccgaga ttcaggacga
    14701 taactaccgt gttgtcgtta tagtccacat ccacctggct gaacttaatt cgtaagtcaa
    14761 caatcggcac aataacgccg cgcagattcg tgacgccttt gataaacgct ggcgtgttcg
    14821 caatccgtgt tacctgatcg tagccacgga tctcctgcac tttcaggata tcaataccgt
    14881 actcttcatc accaagggta aataccagaa attcctggcc tgacggctcg ctggccagct
    14941 ttgttacatt cgtcataccg gtcatattgt taccttttta ctcattcagg cggcggtgtt
    15001 cgccatacgt tgttcgcggt ttatcgcctg caaggcggag acatcaacaa tcagtgccac
    15061 gctgccgtcg ccaagaatgg tcgcagcaga aatgccgggg actttgcgat agttactttc
    15121 aaggttttta accacaacct ggtgttgacc aattaattga tccaccagca aggcgtagcg
    15181 gcgaccgcca ctttgtaaga tcaccgcaat tccctgggtg gcttcggttt tcgcgcccgc
    15241 gacgttgaac actttccaca gttcgacgat gggcagatat tcaccccgca cttccagcac
    15301 ccgctcgccg ccggccagtg gatggagatc ggcttcacgg ggttgcagtg attccataac
    15361 agcattcagc ggcagaatga aaacttcatc cgcaacgcgt acggatatgc cgtcgaggat
    15421 ggccagcgtc agcggcagta aaatgcggat cgtagtgcca gtaccctgct tcgactggat
    15481 ttcgacatga ccgcccatct cctggatatt acgtttgacg acgtccatgc cgacgccgcg
    15541 cccggagacg tcggtgacct gctctgccgt ggagaagcca ggtgcaaata tcagcatcgc
    15601 gacttcgtcg tcgctcatgt tttcgctgac agtcaaacct tgcgaggccg cttttgccag
    15661 aattcgctca cggtttagcc ccgccccatc gtcggtcact tcaatgcaaa tgttgccgcc
    15721 ctgatgttcg gcagacagaa ttaaatttcc gacgctgttt ttacctgcgg cgagccgttt
    15781 ttctggcagt tcaataccgt gatcgaggct attgcgtacc aggtgggtca gcgggtcgat
    15841 aatgcgttct atcaggcttt tgtcgagttc agtagaactg cccaccagcg tcagttctac
    15901 ctgcttgccg agttttcccg ccagatcacg caccagccgg ggatagcgac taaaaacata
    15961 ttccatcggc atcatgcgaa tcgacatcac tgattcctgc aaatcacggg cgttacgttg
    16021 taactgcccc atgctggtta tcaaatcacc atgattaacc gggtccagtt cgctggaacg
    16081 ctgggcaagc atggactggg tgataaccag ctcgccgacg aggttaatta attgatcaac
    16141 cttttctacc gctacacgga tgctggtgga ttcattgctg cgcgtcgttt tttcccgctc
    16201 cacgcggccg gttggcgctt gttcggctgc cagtttaagc actggtgggg tggatatttt
    16261 tggcgagact tctactgttt caaaggtaat ctgatcggct tcaatcacaa aacagagtac
    16321 cgctgtgatg tcatcttcgg cgatgtcgcc cggtaatatt gccgagagcg aatccgcccc
    16381 tttcaccacg tcagttaacg ttgtcagatg tcccagttct tcttccagca ggtcgacttc
    16441 cccggccttc aggcgcgaaa ggataattcg tcgcggcgac tgactgcgac tctgctcatc
    16501 ttgcggttca cttttggcaa ccacacttaa tcgggtcact gcggatggcg tttcgccttt
    16561 cgcttctaat gccagttgac gcaaggcctg gcagatataa tcgaagctgg cggcatccgg
    16621 ctcttgcgac tgtttataag cgtcgagctg ttcttgcatg atgtccttcg tttccaaaaa
    16681 cagattgata atgtcggtgt tgagttgcat ctcacctcgt ctggcttcat cgagcaggtt
    16741 ttccatcaga tgcgtggttt cctgcaaaac gctgaagcca aaagttcctg cccctccttt
    16801 gatcgagtgg gcagcccgaa agatggcatt caattgttcg gcatctggcg cttccggctg
    16861 caaaaccagc aaatgctgct ccatgtcagc caacagttcg tccgcttcat caaaaaatgt
    16921 ctgataaaaa tcgcttatat ccatgctcac gctgtcacct cggttcggct gatggcattg
    16981 tgggaacact gacctgtggt gcaacctcag gtttttccag ggcgcttact ggctcattct
    17041 ggctttcggc gttttcatgc aaaatggcct gttcggcttg tttgttcagt accagcaggc
    17101 tgatgcgacg gttgacggca tcatcaggtc cgcgatcgct taagcgcatc gttgccgcca
    17161 tgccgacgac acgtaacact ttgccgctat ccaaccctcc gaccatcagt tcgcggcggg
    17221 atgcattggc ccgatcggca gaaagctccc agttgctata tcctttctca ccgctggcgt
    17281 aggggaaatc atcggtatga cctgaaaggc taatacggtt gggaataccg ttcagtacag
    17341 gcgcaatggc gcgcagaatg tcgcgcatat agggttcgac atcggcactg ccggttctaa
    17401 acatcgggcg attctggcta tcgatgatct gaatacgtag accttcctgg accagatcga
    17461 ttttgagatg gggacgtaac gcccgcagtt tcggatcgga ctctatcaac tggtcgagat
    17521 caccccgcaa tttccgcaat cgactttgct ccatgcgttt tttcagctct tcgatgttcg
    17581 gctgcttatt cacttccccc tggctttggg tgtaatcatc accaccgccg ggaattgggc
    17641 tttcactatt agaaatgcga tcgccgcccg taaccgcagt cgccagtgga gtccggaagt
    17701 actccgcaat ctgaatcagc tcttttgggc tggagatgga gatcagccac atcaccagaa
    17761 aaaaggccat catcgcagtc ataaagtcgg cataagcaat cttccacgat ccatgtgctg
    17821 ccccgtggct tttggctttg cgtcgtttga cgacaataat cggatgcgct tgattcttca
    17881 tgcttcctcg gttgtcgtct gttgttgcgg atttttcacc gcacgcacat gctcttccag
    17941 ttcaataaac gacggacgtt cgctggaata gagcgttttg cgaccaaact caacggcgat
    18001 aggcggtgcg taaccgttca gattagaaag cagagtgact ttgacgcact gcatcatttt
    18061 gctggtttcg gcgcttttct gacgtaaaac agtcgctaat ggggaaataa atccgtaagc
    18121 caataaaatg ccgaggaaag tccccaccat cgcatgtgcg ataagcgcac ccagctcggc
    18181 ggcaggacga tcggctgaac ctaacgcgtg aacgaccccc attacagccg caacaatacc
    18241 aaacgccgga agtgagtccc cgaccagcgc cagactgttc gccgggactt ctgcctcgct
    18301 ttcgtgcgtc tcaatctctt catccatcag ggcttcgatt tcgaaggtgt tcatgtgacc
    18361 gctgataatc aggcgcagat aatcgacgat aaaatcaagc atgacgctat ccgcgaggat
    18421 gcgtgggtag ctggcgaaga tctcgctctc acggggattt tcaatatcac gttccagcga
    18481 aaacatcccc atctgccgcg atttcgccat caaccgataa agcagagcca gcagatccat
    18541 atacattgct ttggtgtatt tggagcgacg aaacagcaac ggcagcgcct tcagcgtgcc
    18601 tttaatcgct ttgccattat tgccgacgat aaacgaccca atccctgcac cggcaataat
    18661 caccagttca gcgggttgat agagtgctcc aaggcttcca ccggtcatca aataaccgcc
    18721 gaaaactgta ccgagaacaa ccaggtaacc taataagata agcacgacat catccttcca
    18781 ctgttgacca tgacaggatg ttcagtcgtc aggcgttaac gcgcgattgg ggcaaaaaaa
    18841 agcagcggta cgtcgttacc gctgctggaa tgttgcgcct caccgtatca gttaaacagc
    18901 ctgtactctc tgttcatcca gcagttgtgg gataatatcg gcaggattct gggaaagttt
    18961 acgtcttttt actgcccggg atggcggttg acataagctg caggcaaagc tgccaacagg
    19021 ctggtgagcg tgggtaataa aattgccgcc gcagcagttg cagctggaaa gttgcagtaa
    19081 tccactttca acaaaccgca ccaatgtcca ggcacgggtt aatgccagca gtggtccttc
    19141 ttctgcttgt gggcactgtt caaggtataa acggtaggct ttgatcaccg catcgacgcc
    19201 attacacaaa ccggttttca gtaaaaactg ccatgcatta cagaacatcg aagcatgaac
    19261 gttttgttcc caggtcataa accagtcggt tgagaatggc agcatgcctt tcggcggtgg
    19321 gcttccgcgc agttctttat aaagttttat caggcgtccg cgacttaact gtgtttcgct
    19381 ttccagcatc tgcaaacgag cgcccagggt gatcaattcc attgccagct gaatatcccg
    19441 cgcttcctga acaatgcttt tttcactcat gatcaggccc ttttcttgcg cagcgcttct
    19501 tcaggctgat taacatcatt cagcaagcgt gttgagagca tgatgccggt atgaatttgc
    19561 tggagatcgt caacgcggga atcttgcgtc aactgagtaa tcgtctggtg gctgtcaaaa
    19621 cggaagtgac aaaccagttg attggtttct gccagcttaa ccatttgcgg aagagtcagt
    19681 gccgctaacg ttgtcgccat ttcttcattt atgccgagac gaacatagcg gacgctttgt
    19741 cctgaacaat caaacgctgt gcaagtagta aatatgacaa gttgatgtca taaatgtgtt
    19801 tcagcaactc ggaggtatgc attattccca cccagaataa ccaactttat ttttatgcgg
    19861 tttcaccgca ccccgtgatg tcgccgggaa gccccggtaa aaaataatta gcattagaat
    19921 agttgcgata agctgcaata agcagaacca cctttttggt ttaatatgtc cttacaaata
    19981 gaaatgggtc tttacactta tctaagattt ttcctaaatc gacgcaactg tactcgtcac
    20041 tacacgcaca tacaacggag gggggctgcg attttcaata atgtgtgatg cagatcacac
    20101 aaaacactca attacttaac ataaatgtat aagtcatact tttgttttgg gtgtatttca
    20161 atctgttaaa aagtttttcg ctacgctagc aagcaaaaat gaaaacagga ataatcgaaa
    20221 tgggatgttg cgcacagtca aaataactca ccgtaaataa tcatctgcta taaataatca
    20281 ctttcatgca ataccagata agctattttt aaacagacac ttaccgcaca acaaactaat
    20341 taaatacaaa gaaaggcaac aatcaactta atgttaatga aatgttttac atatattaac
    20401 cacttgttta atgcggagaa tcagtacact attttcttat aattacattt gaaattatat
    20461 gatcaccggg agtgattgat taattgtctt tactaataat cagactaata tttaccagtt
    20521 tgaccgagtt gggattgcgt cgtttctcca ttaggagtaa agctttaatg tcacctgaag
    20581 ttcacagaat aaggaacagg ttatgagcta tagcaatatt cttgtcgctg ttgcggttac
    20641 accggaaagt cagcaactgc tggcaaaagc ggtatctatc gccaggccag taaagggaca
    20701 catcagttta attactctcg cttccgaccc ggaaatgtac aatcaattag ctgcgccgat
    20761 gcttgaagat ttacgcagcg tgatgcagga agaaacgcaa agctttcttg ataagttaat
    20821 tcaggatgcg gggtatcccg ttgacaagac gtttattgcc tacggtgagt taagcgaaca
    20881 tattctggaa gtatgtcaca agcatcattt cgatttggtg atttgcggta atcacaatca
    20941 cagtttcttt tcgcgagcat cctgctcggc gaaaagagtt attgcctcaa gtgaggtcga
    21001 tgtgctgtta gttccactta cgggagatta accgctccta cgcaagcttt ggaaaggtag
    21061 caactttatc gcgctgctgg ctttccgcgc ttcgcggaac tatctgcttt aggtcgctaa
    21121 tgaagcactc ctgccagtgg ttaatatcgt ttttcacgat aacgtccagc atttctgcat
    21181 gacgggaaat acgttccgcc agcgacatag tcaatgcacg atccagcgca gctgcaactt
    21241 cgtcacgatc gtaggggtta acaattaacg ccgacgttaa ctcgtttgcc gctcccgcaa
    21301 attgcgaaag aacaagaacg cccggattgg ctgggtcctg agcagcaaca tactcttttg
    21361 ctaccaggtt catcccgtca cgcagtggcg tcactaagcc cacgtcagag tagcggaata
    21421 ttttcatcag taatttacgg tcaaaatgct gattcaaata ataaagcggc gtccagccta
    21481 attgcccgta tttaccatta attcgtccag cttcattttc gagctgatga cgaatatcct
    21541 gataggcttg cacatcacca cgcgacgttg gtgcaatctg ggtataacga attttaccat
    21601 gatgctgcgg atatttttcc agcaacgctt cataggcgag aaaacgctct ggcaaacctt
    21661 tggaataatc cagccgttcg acagaaaaga tattttgtac gtttttcagt tccgctttaa
    21721 gttgcgccag ttttggcggc agtggcccgg cagcctgttt ggctatttct ttcggttcaa
    21781 tgccgatcgg gtagacttct gttcgaaatg ctttgcccca ggctgtatgg ctttttgcgc
    21841 tacgtgtcgt gacgcgggtc aggttagaaa gacaatccag gaacgccaga cgatcgtttt
    21901 ctgtctggaa acccagcaaa tcataatcac aaagctgttc aagcaaggtg tcatatgtcg
    21961 gcagcgcgtt gaagatttcc ggtgtcggga aaggaatatg cagaaagaaa ccaatgcgat
    22021 tattcactcc ccgtttgcgt aattcatgcg caaatggcaa caggtgataa tcgtggatcc
    22081 agataatgtc atcgtcttgc aacagcggca gtaatttatc tgccagcaac gcatttacgc
    22141 gtagatagcc gtcccaggca ggacgctgaa attgcaccag atcgagccga taatgaaaag
    22201 cgggccagag aacggcattg gagaattggt tgtagtattc gtcaaggtcc tgttcgctga
    22261 ggttaaaaga ggcccacgta atgttacctt ttttcacctt ttttagcggc tgatcctcat
    22321 tccctgtttc accactccag ccaaaccaca gtccgcctgc ggctttcagt gcccccagta
    22381 tgccaacggc aaggccaccg gcactggcgg cgtgctcgtc tggtggtgca atccggttag
    22441 atactacgac taaacgactc atagtcatca ctcctgttat tttctctttt ttgttgtaat
    22501 gcggtggtta tcatttcaag ccagctccag acatccggca cacccgccag tcgccatgat
    22561 gcctgagttg cacctgtgcc aatttttact gacattccgc ccagtcggtt aacgactgcg
    22621 aagccagatt catcggttaa atcatcgccc agaaatacgg gcgttcgccc gataaaggga
    22681 gcttcctgca taaaagctgc aattgcctca cctttactgg tacctctcgg tttgatctcg
    22741 acaacacact ttccctgctg taacgccatt tgtggccaga tctgagtaat acgttgcgct
    22801 aatgtcatta atgcgtcttc atgctgcgga gcctgacgat aatgcagcgc aaaagccatc
    22861 cctttcgcct ccagctccgc gccgggatac tgagcgatga ctgtatgcag ttgcacgcta
    22921 atatcatgcg caatcgcatc cggcagatga acgatatgtg ttttaccatt gatgtcacgg
    22981 cgctccgccc catgcacgcc cgctaacggg aagcgataag gttttgccag tgcgtcaagc
    23041 tccaccattg agcgccctga tatcaatgcc aatgcaccat cacttgcggt tgccagtagc
    23101 tgtagtcctt gcagaatatt gtcaggcacg acgacctgat cgggatgcgg tttgatttcc
    23161 gccagcgttc catcaagatc aaaaaaccag gcatatttcg cggatagttc aggggtttcg
    23221 gttaacggtt ctgtcacccg gttctcctcc ttctcttttc ttattgtgtt gcgcagaacg
    23281 cgctttacag acatgtaagt atagacagtg tgacgggggt cgccatttgc aacgaagaac
    23341 agccaaccgt tatggcggtt ggctatggtg ggaaaaaacg ctaaattgtt gcagaaaaaa
    23401 gcatcagaca gtgcgtttcg ctttttgctt gtaacggtcg aagatcaccg ctgccagcag
    23461 gattaagccg cgaaccacgt actgcgcgaa aggagaaata ttaagcaggt tcatggcgtt
    23521 ttccacggtg cctaaaatta agatacccgc caccacatat gagatttttc cgatgccacc
    23581 tttcagagaa acgccaccta aaacgcaggc ggagataaca atcagctcat aaccaatcga
    23641 cgtcattggc tgcccactgg tcatacgtga agccagaata attccggcta tcgctgatac
    23701 caggcctgag agaacaaaga taataatttt ggtgcgaaca accggtacac ccgccagacg
    23761 cgcggcctct tcgttcccgc caatcgccag ggtgttacga ccaaaggtgg ttttattcag
    23821 cagcaaacca aagataatca gacacgcgac ggtgagccag attggcgcag gcagaccgaa
    23881 ccagttggcg taaccaaggg caaagaagct ttcatcttcg ataccgaccg ctttaccgtc
    23941 tgaaatgatg tacgccagac ctcgaacaat ctgcatcgtt gccaatgtcg tgatcagagc
    24001 atttattttc agtttggcga taacaaagcc attgaccagg ccacagagaa cgcccagcaa
    24061 caaccccgct gccacgccaa tccacaggct ttcagtcagg ttaataacca ccgccgtggt
    24121 gacacccgca caggcaatta cggaggcgac agaaaggtca aagtcaccgg aagcgaggca
    24181 gaacaacatg ccacaagcca ccatccccga catggaaatt gccaggccca accctttcat
    24241 attaatgaag gtggcaaaat ttgggacaaa aatggcacag gcgataaaga gcaccgcaaa
    24301 caccaccagc atgccgtact gatcccagat acgcccgaag ctgaatgacg acttaggtgc
    24361 gccagacccc gatgtagaaa cagaagacat catactctcc ttactcaggc aacagcctgg
    24421 ctgactttag gcatcgcaag gctcagtgcc tgacgctcat ctgcctgctc gtgtaacaat
    24481 tcaccggcga tttcaccttc ccgcatcacc acaatccggt cggcaacgcc gaggacttca
    24541 ggtaagtcgc tggaggcaaa cagcaccgcc acgccctgcg ccgccagcgc ataaattacg
    24601 ttatatattt cgtgcttagc gccaacatca atgccgcgcg taggttcatc cagcaaaatg
    24661 accttcatct cttccgataa ccagcggccc agaatggctt tttgctgatt tccgcctgag
    24721 agattcatga tcagttgctc cgcgcccggc gttttgatgt tgagcgaacg aatgtggtga
    24781 tcggcattgt tttcttccca accgttgttg attacacaac cgccgagcac atgtttacgt
    24841 ctggcactga tgttgatatt gtcgcgaacg gagtgcacgg gaataatgcc ttccgctttg
    24901 cgatcttccg ggcagagcat catgcctgcg gcaatggcgt ggctcggttt acgaatatcg
    24961 atcggctgtt ggtcgatata aacctgaccg gcggtgattt gcgtcccgcc aaacatgcct
    25021 ttcattaatt cgctacgccc cgcccctacc agaccaaaca gcccaacaat ttcaccactg
    25081 cgaaccgcca gacttattgg cgtacgcacg cctggtgctt tcacagcatc aagacgtagg
    25141 cgctcctcgc cataactacg cggttgccag ccgtagatat cgccaatgtc gcgcccgacc
    25201 atcgcctgca ccagcgcgtc gtggtcaacc tgctgcatat cggtaaaggt tttgacataa
    25261 cgtccatctt taaagacagt aatggcatcg ctgagggcaa atatttcttc catacggtga
    25321 gaaacgtata agattacccg cccctctttt cgcagttcac gaataacgcg gaaaagattg
    25381 tcgatttcac gggcagagag ggagctggtt ggctcatcaa aggcgataat tttggcgtta
    25441 cgcgccagcg ctttggcgat ttcaaccatc tgccactgac caatggagag atatttcagc
    25501 ggcgtgtccg ggtcaatatc cataccaaga tgtttaagtt gtaaacccgc ctcataattc
    25561 agcaatgagc gattcacaat gccgccttta tgcggcagct ggccgagata gatgttttcc
    25621 gcgacggtca tttccggcac gagatgcagt tcctggtaaa taatcgccac gcccgcgtta
    25681 agtgctgcgg tcgtgtcgga aaaggacatt tcctgcccat taatcactac agaacccgtg
    25741 gttggcgcat agttgccgct gaggattttt aagagagttg attttcctgc gccattttca
    25801 cccatcaacg catgaacctg accggcatag cagtcaaaac taatatccgt cagcgcctta
    25861 acgccgggaa acgttttacc gatgccgcga aatgagagat acggggtaga ctgttgcata
    25921 acgtctccgt gaatcactgg tcgttcacac cccctctgca tcatgcagag gggaattttt
    25981 ccggcaaatt acttaccgcc taaacctttt ttctccagtt cttctttaaa gttgtcacgc
    26041 gtgatcagta ccacgtcggt aacttcggta aattttggcg gttcaacgtc ttttgctacc
    26101 cagttgtaaa gcatttcgct ggatttatag ccatgtacgt ccgggcttgg cagcagggaa
    26161 ccgtagaagc cggttgcctg tgctttagac agttcgctca ccgcatccac accgttaatg
    26221 ccaatgccga tgatatcggc cgctttaaag ccctgacctt ccgtcgcgcg tacgccgccc
    26281 agcacggtgc tgtcgttcat accgacgatc agccaatgtt taacttccgg atgttgaacc
    26341 agcattgagt tggcagcgtc aaatgccccc gggatgtcgt tagatttggt aggtacctga
    26401 taaatttgtt tttccgggaa tccggccgct ttcagcgcat ccatagatcc cgtagtacgg
    26461 cggcgggcgg tatccagttc gttggcggta atcgccatca ccgcgctttc tttgacatcc
    26521 cagccacgtt tctgcatctc tttatacagt tcctggccct gacgttcgcc aattttagtc
    26581 gccgccatca tcaccagcgg aacggtatcc attggcttac ctttggcgtt aacaaactgg
    26641 tcatccacgg caatgacttt catatcgtag ccacgcgctt tcgcgacgat ggcagagccg
    26701 agtttggggt ccggagtaca aataacgaaa ccttttgcgc cactggcagc caggctgtcg
    26761 atcgcgttca atgttttttc gccatccggc acggcaatct taataacctc aaaccctaaa
    26821 tccttcccgg ctttatcggc aaacttccat tcggtctgga accacggctc ttccggttgc
    26881 ttcaccagaa aaccgagctt caggttctcc gccatagcgg attgtgacat aacggctgcc
    26941 agaccaatgg ctgccagggc tttagtaaat ttgtgcatgg ttctctccag ctttagtgtc
    27001 gttttgtgta gggcaaaaac gaatgacatt cgttaaatta atcggaaaac aaagcattac
    27061 cttttaacta aaagataagt gactgtgttg acatagtttt agcgagaaat taattctcca
    27121 taggagagca atatcacatc gcagaattac agtgagaacg tgcataaatt tagcgggaaa
    27181 agacataagg gaaagccaat ttgtcagaca aattgtcgaa tgcacagcag attaatccat
    27241 aagattagcc tggaaatcct tgttgtcttt ggtacccatg cgggatgtct tctttttaac
    27301 cagtcaatag gccgcattac ctggcgttga gtttttgaaa tggtgtaata accgcaactc
    27361 aaagatgtgg aaaatgcacg tcattcattt cgtcattaat tatcactgtg ctcattaatt
    27421 aacagaacac gtataatgag agccatctcg caaaaatgaa aaaacgtttt ataaaatcat
    27481 cacttcatca taaattcaaa ttcattgatt aatatcaaca agatacaaaa agcactatca
    27541 ttaaaattca ttgcagttac attgatttca tcaatgaaat gtaaaaatat ataaacttga
    27601 tgatttaagc attttcttat acccgttcag acgttattct tatttcagat catcgtcaga
    27661 attgactcca cgatcacatt tcggaccggc agaaaggaat tattctgcaa acagtaatta
    27721 tggtgttttg atttatcttg cacctctcca cttctggata taaggatatt aggtatggca
    27781 accgctggaa tgcttctcaa actcaactct caaatgaacc gcgagtttta cgcatccaat
    27841 ctctaccttc acctgagtaa ctggtgttct gaacagagtc tgaacggcac cgccactttc
    27901 cttcgcgccc aggcacagag taatgtgacc caaatgatgc gcatgtttaa ctttatgaag
    27961 agtgtcggcg ctacccccat cgttaaagcc attgatgttc ccggtgaaaa actgaactct
    28021 ctggaagaac tgttccaaaa aacgatggaa gaatacgagc aacgttctag tacgttggca
    28081 cagttagccg atgaagcgaa agaactgaat gatgattcaa ccgtcaattt cctgcgcgat
    28141 ctggaaaaag aacagcagca tgatggtctg ttgctgcaaa ccattcttga tgaagtgcgc
    28201 agtgcgaaac ttgcgggtat gtgccctgtg cagaccgacc aacatgttct gaatgtcgtg
    28261 tcacaccagc tgcattgatc atcatcggcg ctaatgcatt gcgccgatga aggttttgag
    28321 aaaccgctgc ctcatctgtt tgaagcagcg gtttttttaa tgggattcac cctgtggggt
    28381 aaacttgagt tcaataagcg cgatggcttt ttggattgcc cgcatggtga ccgggtctgc
    28441 ggcggcggga tggttagtaa agtcgatatt cttcagctga ctggacattt tttcacgaac
    28501 ttcaacgggc gcgattacat cgagaacatc cagaatttgt ttgataacca actggcaagc
    28561 aaccacatca gaaaccagtt cctgatcggc attcagcggc tgggacatcg taaactcctg
    28621 atagcatttt gaaagccgtt atagtagcgg cttcacatct tcagcgatag tcacatccac
    28681 cgtcatcagg acacaaaaaa acctgccgga gcaggttttt tgttatcgga acatattgcc
    28741 tggcggtacg tctttgaacg tcttgcaata gttattgaac atacttttca ggattttgcg
    28801 cagtttcatc gcggcactcc gactatttgt tatacaggtg ttattgtctt tgcgcttata
    28861 atatgacaac catcacaaaa atcaaacttt atgtgataca aatcacataa ataccccttt
    28921 aatgttataa aaatgataat caaaaaacag cccccctatt tctgacacct acagatggca
    28981 agaaatagcg cctgccaggc gtcttttccg gccattgtcg cagcgctgta acgcgtaaaa
    29041 tagtgctttc tcttactctt ctggctggac catgagactt ctgattctga ctctttcatt
    29101 aataacgctg gcggggtgta cggttactcg ccaggcccat gtgagcgaag ttgacgcggc
    29161 aacaggtatt gtacggttgg tttatgacca ggcttttttg cagcatgccc ataccgatcg
    29221 ttatgtcagt cgcgggatcg ccgatcgcgc atgccagcag gaaggctata cccacgcggt
    29281 cccctttggt cagccagtag gcaactgtag cctttttgcg ggttccttat gtttgaatac
    29341 ggaattcact ttgtcatatc agtgccatca ttccgccttc cctgtctttc tctaaatatt
    29401 ttaatcagcg aggggatctt cgctgattaa agaaatagcg gtaatgcgtt ttattaccat
    29461 tcgtattttt aataattgaa gtttatattt taccttttgc aaataataaa ataacaaatt
    29521 atagtgacgc cacagcaaca aatataacct ttgtggagca ctatcatgct gaaaccagaa
    29581 atgattgaaa aacttaatga gcagatgaac ctggaactgt actcttcact gctttatcag
    29641 caaatgagcg cctggtgcag ctatcatacc ttcgaaggtg ctgccgcgtt cctgcgccgt
    29701 cacgcccagg aagagatgac gcatatgcag cgtctgtttg attacctgac tgataccggc
    29761 aatttaccgc gtattaatac cgttgaatct ccgtttgctg aatattcctc acttgatgaa
    29821 ttattccagg aaacctataa acacgaacaa ttaatcaccc agaaaattaa cgaactggct
    29881 catgctgcaa tgaccaatca ggactaccca acatttaatt tcctgcagtg gtatgtttct
    29941 gagcagcatg aagaagagaa actgttcaaa tcgattattg ataaattaag cctggcaggc
    30001 aaaagcggcg aaggtctgta ttttatcgac aaagaactct ctaccctcga cacacaaaac
    30061 taatgctctc cggcggcagg tttactgccg ccgtttcaaa tcagtgacgg caaatcttac
    30121 tctgatcggt cgaaaaaccg tctttcgaag gtataaattt gccttttgct gccagaaacg
    30181 ctaccagctc tcccgctgtc atcccttctg ccgagcaggt gtgaaaacgt gcctgttcac
    30241 caaaacgcgc tttaatcgca gcttccagac tggcatgcgt atattgctcg cctgattcaa
    30301 tcatcatatt taacacttca tgaccgtgaa tagagtccat cgtcccttct caaaaaaagc
    30361 ctagcgtagc gattgccgct tatgaagact ttgcgccagc gcaggactga atgcttttta
    30421 ttgtacattt atatttacac catatgtaac gtcggtttga cgaagcagcc gttatgcctt
    30481 aacctgcgcc gcagatatca ctcataaaga tcgtcaggac agaagaaagc gtgaaaaaca
    30541 gaaccctggg aagtgttttt atcgtggcgg gaaccacaat tggcgcaggc atgctggcaa
    30601 tgccgctggc tgcggccggt gttggtttta gcgttacgtt aatcttgttg attgggcttt
    30661 gggcgttgat gtgctacacg gcgctattac tgctggaggt gtaccagcat gttccggcag
    30721 ataccggtct gggcacgctg gcaaaacgct atctgggacg ctacggtcaa tggctgacgg
    30781 gcttcagtat gatgttctta atgtatgctc tgactgcggc atacatcagc ggtgccggtg
    30841 aattgttggc ctccagcatc agcgactgga caggtatttc aatgtcggca accgctggcg
    30901 tgctgttgtt cacttttgtt gccggtggcg tggtttgtgt tggaacatcg ctggtcgatt
    30961 tatttaaccg ttttctgttc agcgccaaaa ttatttttct ggtggtgatg ctggtattgc
    31021 tgctaccgca tattcacaaa gtgaatcttt taaccctgcc gttgcaacag gggctggctc
    31081 tgtcagcaat cccggtgatt tttacctcat ttggttttca cggtagcgtg ccgagtattg
    31141 tcagctatat ggatggcaac gttcgtaagc tacgctgggt gtttataacc ggtagtgcga
    31201 tccccctggt ggcatatatt ttctggcagg tggcaacgct tggcagcatt gattcaacaa
    31261 cctttatggg attgctggct aatcatgctg gattaaacgg gctgttacag gcgttacgcg
    31321 aaatggtggc ctctccgcat gttgagctgg cagtgcattt atttgctgat ttagccctcg
    31381 ccacgtcatt tctcggcgtt gcgttaggct tatttgatta tctggctgat ttatttcagc
    31441 gttcaaatac cgttggtgga cggttgcaaa ctggtgcaat tacctttctg ccgccgttgg
    31501 cgtttgcact gttttatcca cgaggatttg tgatggcgct gggttacgcc ggtgtggcgc
    31561 tggcggtact ggcattgatt atcccttcgc tgttgacctg gcaaagcaga aagcacaatc
    31621 ctcaagcggg ttaccgggtc aaaggtggtc gtccggcgct ggtggtggtg tttctctgtg
    31681 gtattgctgt gattggcgtg caatttttga ttgcggcagg gttgttacca gaagtggggt
    31741 gattagatag cctcaaattc cttattgggt gccagaatta acgctgacac ccaatttggc
    31801 ctcttaatgc aggcagcact gcttaaattt cttaccacta ccgcacgggc aaggatcgtt
    31861 acgccccggt ttctcttctg ctttgatcgg ttgctgaaca gctttttcct gcggatgcgc
    31921 catccagtac gcatgtagat caagcgccgc cagtcgaatg gcatctacgc tctcttcaaa
    31981 cgcttctggc gacattttct ctacccgctc gaagttttcc tcagtaccgt gcagcgcaat
    32041 cgcctccagc gctggtttta acgaatcggg caacgttgac cagtcagaaa gtgccacgcc
    32101 ccgcatatag ccaaagcacc actcctcaac aatcgtcagc tcgctgccat caacttctcg
    32161 caagccgaat aacggctcaa actgctccgg gaattcgttc agacgctctg cggtatcggc
    32221 catatgttga aaagccaggt tcataaagcg cgtcatctct ttctctgacg cccagcgcgg
    32281 cacatagtca gccccacccc acacggcaac cagccactgt tccggttcaa tctcttgcgg
    32341 agaactcaac accgccgtca ataaaccgtc cagctccgcc acatcaagga tggcgtggtc
    32401 agtgttgtat ttggtcagaa tatcgtccag ccattccaac tcactttcgt ttaacggtcc
    32461 cgttttcata cgcttttcct tgtggatctc aactcgccag cacctatctt acatgccggt
    32521 ccgtatcaga gatacttttt gagtggcttt gctggtgatt aaaaattaag gagggtgtaa
    32581 cgacaagttg caggcacaaa aaaaccaccc gaaggtggtt tcacgacact gcttattgct
    32641 ttgattttat tcttatcttt cccatggtac ccggagcggg acttgaaccc gcacagcgcg
    32701 aacgccgagg gattttaaat cccttgtgtc taccgattcc accatccggg ctcgggaaga
    32761 aagtggaggc gcgttccgga gtcgaaccgg actagacgga tttgcaatcc gctacataac
    32821 cgctttgtta acgcgccaaa ttcttcaggc ctttcagcca gacatccgct tgacgccgat
    32881 gtcttttaaa ctggagcggg aaacgagact cgaactcgcg accccgacct tggcaaggtc
    32941 gtgctctacc aactgagcta ttcccgcatt catcaagcaa tcagttaatc acttgatttt
    33001 attatcgtct ggcaatcagt gccgccgttc gatgcgttgc attctactta cctggcgcga
    33061 tgagtcaacg atatttttca ccacttttga tcgtttgctg aaaattacgc cgaaacgatc
    33121 actgatcaag caaatctgca cgcgcagcgc tcaaatattg caacattgac cacagagtca
    33181 gtaccgcagc cacaaagaaa agtgcaatac cggcgtactc aacccaaatg ttcggacgcc
    33241 acagcagcca ggccaacgcc accatctggg cagtggtttt cactttccca atccaggaga
    33301 cagccacgct actgcgttta cccaactccg ccatccattc gcgtagcgca gaaataataa
    33361 tttcacgggc gatcatcgtt gccgccggta aggtcaccca ccagctgtga taatgctcgg
    33421 ttaccagcac catggcgata gccacgagaa ctttatctgc gacagggtca aggaaagcac
    33481 caaaccgggt actctggttc cagcggcgtg ccagaaaacc atcgaaccag tcagtcaccg
    33541 ccgcgacgca gaaaatgagc gcggcggcaa acggcgacca ggtgacaggc agataaaaga
    33601 ccaatacaaa gaatgggata aggatgacac ggaacagtgt aagcaacgta gggatattaa
    33661 attgcataat gacgggtaac tatctgttgt cagtaagatt acccctatgt tgctacagag
    33721 acatcaatgt ttcaacgacc agaagatctt ttctgccaga ccttgcgaaa tacccggcac
    33781 ttttgcaatt tcctcgacgc tggcgttacg taaaccttgc aaaccgccca tatatttcaa
    33841 caacatttgc cggcgttttg gcccgacgcc ttcaatggtt tccagggaac tggtattttt
    33901 gaccttcgcc cgttttttac ggtgcccgcc aatcgcgtga tcatgtgatt catcgcgaat
    33961 atgctggata acatgcagcg cgggagaatc tggcggcaaa ctgaatccct caccttccgg
    34021 ctcaaagaac agcgtttcca gcccagcctt acgatctgct cctttggcaa cgccaagtag
    34081 cagcggatga tttttatccc atgagacatc cagttcggcg aagacatttt tcgcctgcgc
    34141 aagctggcct ttgccgccgt cgataagtat cacatccggg atcttactgt cgtcgatggc
    34201 tttaccataa cgccgacgca gcacctgatt catcgccgca taatcatcgc ccggcgtgat
    34261 gccagtaatg ttatagcgcc gatactccgc acgcagcggg ccgttagcat caaacaccac
    34321 acaggaagcg acggtttgtt cacccatggt atggctgatg tcaaagcact ccatccgctt
    34381 cacttccggc aatttcaaca cactggcaag tgctgtaagc cgctggtgaa cggtagattg
    34441 ctgcgaaagt ttgctggtta aggccgtcgc cgcattggtg cgcgcgagtt tcagataacg
    34501 cgcccgatcg ccgcgaggtt tggtttgaac attaatcttg cgtcccgcca gttctgaaag
    34561 ggaatcggcg agcagcgttt tatcgctaag attaaaatcg agcaggatct cacccggtaa
    34621 ggtgcgcatc tggctgcctt gtaaatagaa ctgacctacg aaggtttcta ccacctcgct
    34681 cagttccgta ccgccaggca ctttcgggaa atagctgcgg ctgccgagca ctttgccctg
    34741 acgaatgaac aatacgtgga cacaagccat gcccgcatcg aacgccacac caataacgtc
    34801 gaggtcgtcg ccggtattgg aaacgaattg tttttcggtg acgcgtcgca ccgcctgaat
    34861 ttggtcgcga atacgtgccg cttcttcaaa ctccagattc tggctggcag tttccatacg
    34921 actaatgagt tgcgtaagca cctgatcatc tttgccagac aaaaacaggc gcacatactc
    34981 gacctgctga gcgtattctt cttcactcac cagtccttca acgcacggtc ccagacagcg
    35041 ccctatctga tattgcagac acggacgcga gcgattgcga taaacactat tttcgcactg
    35101 gcgaatgggg aaaatctttt gcagtagcgc cagtgtttca cgtacggcat agccattcgg
    35161 gaacgggccg aaatattcac ctttggcatg cttcgcacca cgatgcatcg ccagacgcgg
    35221 gtgggtatcg ccactcagga agataaaagg ataagattta tcatcgcgta gcaaaacgtt
    35281 gtaacgcggc tgatagagtt tgatgtagtt gtgttccagc aacagcgctt cggtttctgt
    35341 atgagtaacc gttacatcaa tttgctggat ctgggcgacc agcgcttcgg ttttgcgcga
    35401 agtgaggttg ctacggaaat agctggaaag ccgttttttc aggtctttcg ctttgccgac
    35461 atagataacc gtaccaccag catcgtacat gcgataaacg cctggctggc tggttacggt
    35521 ttttaaaaac gcttttgcgt caaactgatc actcactgac ttgataatgt ctccgcatta
    35581 cacagaccat ggcgaattgc caggtgagtc agctcaacat cgccatgaat gtttagttta
    35641 ctgaacatac gatagcggta gctgttcacc gttttcggac tgagattgag ctgttctgag
    35701 atctcattga ccttctggcc cttggtgatc atcagcataa tctgcaattc acgttcagac
    35761 aaactggcaa atgggctttc tgttttttct ggttcgatct ggcttaacgc catttgttga
    35821 gcgatgtcag aagcaatgta acgctgccct gaatagacag aacgaatcgc actcacgact
    35881 tcctgcggag ccgcgccttt gctgaggtag cccgcagcac cggcctgcat gactttcgct
    35941 ggtaaagggt tttctgtatg gacggtaagc atgatgattt tgacatcagc tgtggaacgc
    36001 gcgattttac gcgtcgcctc aagaccgcca atgcccggca tactcatgtc cattagcacc
    36061 acgtcaacgg catttgcccg acaccactta acggcgtctt caccgcacga tgcctcaccg
    36121 acgactttta taccctttat atcttccaga atgcgtcgta tccctgcgcg caccagttcg
    36181 tggtcatcaa caagtagaac gttgatcaaa ggaatatctc cagaaatagg gataacgcta
    36241 ctgatagtta gtcattcgta tattagcggt ttttattgca actttgaaac gttaaaaatg
    36301 gtgggtattc gatttttctc tcgtttttgt caattcgatt gtccacagtt atggtcacgc
    36361 ccgtcaccaa cggcttaccg gatcgtttca cagtaagccc tgcgacgaaa tgtgacaaaa
    36421 attaccttta ttcagcaaaa atgaaaatca gcccgctgaa tatgtaacat taattaaccc
    36481 gaacaatacg ggcaaaaaac attcatgata aaaatattta ttggtcatta tattaacgca
    36541 tttaatagca ccgttgacga tacgctcaaa aaacaaccac tgctattttt agcaaagctt
    36601 atggtatact ccgccgcctt aacatttttc accgcaaatt ttcattgcaa catgacgagg
    36661 aaaataaatg agtacgcctg atttttctac tgccgagaat aatcaagaac tggcaaatga
    36721 agtctcctgc ctgaaagcga tgctgacgct gatgctgcag gcgataggac aagctgacgc
    36781 gggccgcgtg atgttaaaga tggaaaaaca gcttgcgctg atcgaagacg aaacccaggc
    36841 tgcagtattt tccaaaacgg ttaagcaaat taaacaagcc taccgtcagt aatataaaac
    36901 cggctgatag cgtgcctttc agccggtttt tgcatctggc acgcaggaca gaaaagagat
    36961 caaattaagc cagtagcggc cgcgtaacag gcaacctggg tcttattcgg tgcattgatt
    37021 tttttctgca tgttttt
//
LOCUS       DADXDL010000047        36226 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.047, whole genome shotgun sequence.
ACCESSION   DADXDL010000047 DADXDL010000000
VERSION     DADXDL010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36226)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36226)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36226
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.047"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            282..1190
                     /locus_tag="IRB70_002612"
     CDS             282..1190
                     /locus_tag="IRB70_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBC0632511.1"
                     /translation="MKAPVSLTSFRPQKSLAIAIGVLAVVVLPFLSYYTVNEGERGIL
                     LRYGKIVKVAEPGLGFKIPFMESVEKISTRNQAVVYQGLQAYSRDQQPAQMTVSVSFH
                     IKPSEAGAVYTTYNTIEALKDRLIVRQLPTQLENVFGQYTAISAVQDRTKLVQDLQNA
                     MRKAVVGPVVIDGVQIENIDFSDAYEKSIEDRMKAEVAIATRKQNLETEKIQAQIAVT
                     QAQAEADSKLAAAKAEAETIRVRGAAEAETIRLKSAAEAEAIRLRGEALRENPGLVAL
                     TTAERWDGKLPDTMIPGSTVPFISTK"
     gene            complement(1409..3400)
                     /gene="tkt"
                     /locus_tag="IRB70_002613"
     CDS             complement(1409..3400)
                     /gene="tkt"
                     /locus_tag="IRB70_002613"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708699.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBC0632512.1"
                     /translation="MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDF
                     LKHNPQNPSWADRDRFVLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPE
                     VGYTAGVETTTGPLGQGIANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMME
                     GISHEVCSLAGTLKLGKLIAFYDDNGISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDG
                     HDAASIKRAVEEARAVTDKPSLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQ
                     LGWKYAPFEIPSEIYAQWDAKEAGQAKEFAWNEKFAAYAKAYPQEAAEFTRRMKGEMP
                     SDFDAKAKEFIAKLQANPAKIASRKASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSG
                     SKAINEDAAGNYIHYGVREFGMTAIANGISLHGGFLPYTSTFLMFVEYARNAVRMAAL
                     MKQRQVMVYTHDSIGLGEDGPTHQPVEQIASLRVTPNMSTWRPCDQVESAVAWKYGVE
                     RQDGPTALILSRQNLAQQERTEEQLANIARGGYVLKDCAGQPELIFIATGSEVELAVA
                     AYEKLTAEGVKARVVSMPSTDAFDKQDAAYRESVLPKAVTARVAVEAGIADYWYKYVG
                     LNGAIVGMTTFGESAPAEQLFEEFGFTVDNVVAKAKALL"
     gene            3678..4436
                     /gene="loiP"
                     /locus_tag="IRB70_002614"
                     /gene_synonym="yggG"
     CDS             3678..4436
                     /gene="loiP"
                     /locus_tag="IRB70_002614"
                     /gene_synonym="yggG"
                     /EC_number="3.4.24.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metalloprotease LoiP"
                     /protein_id="HBC0632513.1"
                     /translation="MKIRALLVAMSVATVLTGCQNMDSSGLLSSGAEAFQAYSLSDAQ
                     VKKLSDQACQEMDSKATIAPANSEYARRLTTISRALGDNINGQPVNYKVYMAKDVNAF
                     AMANGCIRVYSGLMDMMTDNEVEAVLGHEMGHVALGHVKKGMQVALGTNAIRVAAASA
                     GGIVGSLSQSQLGDLGEKLVNSQFTQRQESEADDYSYDLLRQRGISPAGLATSFEKLA
                     KLEEGRQSSMFDDHPASAERAQHIRDRMSADGVK"
     gene            complement(4640..5560)
                     /gene="speB"
                     /locus_tag="IRB70_002615"
     CDS             complement(4640..5560)
                     /gene="speB"
                     /locus_tag="IRB70_002615"
                     /EC_number="3.5.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="agmatinase"
                     /protein_id="HBC0632514.1"
                     /translation="MSTLGHQYDNSLVSNAFGFLRLPMNFQPYDSDADWVITGVPFDM
                     ATSGRAGGRHGPAAIRQVSTNLAWEHNRFPWNFDMRERLNVVDCGDLVYAFGDAREMS
                     EKLQAHAEKLLAAGKRMLSFGGDHFVTLPLLRAHAKHFGKMALVHFDAHTDTYANGCE
                     FDHGTMFYTAPKEGLIDPNHSVQIGIRTEFDKDNGFTVLDACQVNDRSVDDIIAQVKQ
                     IVGDMPVYLTFDIDCLDPAFAPGTGTPVIGGLTSDRAIKLVRGLKDLNIVGMDVVEVA
                     PAYDQSEITALAAATLALEMLYIQAAKKGE"
     gene            complement(5696..6427)
                     /locus_tag="IRB70_002616"
     CDS             complement(5696..6427)
                     /locus_tag="IRB70_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632515.1"
                     /translation="MKKWKVRSALVALIVLLAGCSSNAQYNSSASGNVGTAWGGDVHS
                     TVQGVSAERAWRDPAEMIVISYSTNVPSGYDRVYSIRINELEYAIRDGNFNSLPITRV
                     YDSSNNEPRYIVHARVGMNYQLYVRNYSRNTNYEIVATVDGLDVLNGKQGSLNNNGYI
                     VNAGDSLAIKGFRKDKHTEAAFQFANVADSYAANSAQGDVRNTGVIGFAAFELQGPAK
                     NALPPCSGQAFPADNNGYAPPPCRK"
     gene            complement(6573..8549)
                     /gene="speA"
                     /locus_tag="IRB70_002617"
     CDS             complement(6573..8549)
                     /gene="speA"
                     /locus_tag="IRB70_002617"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biosynthetic arginine decarboxylase"
                     /protein_id="HBC0632516.1"
                     /translation="MSDDMSMGLPSSAGEHGVLRSMQEVAMSSQEASKMLRTYNIAWW
                     GNNYYDVNELGHISVCPDPDVPEARVDLAQLVKTREAQGQRLPALFCFPQILQHRLRS
                     INAAFKRARESYGYNGDYFLVYPIKVNQHRRVIESLIHSGEPLGLEAGSKAELMAVLA
                     HAGMTRSVIVCNGYKDREYIRLALIGEKMGHKVYLVIEKMSEIAIVLDEAERLNVVPR
                     LGVRARLASQGSGKWQSSGGEKSKFGLAATQVLQLVETLREAGRLDSLQLLHFHLGSQ
                     MANIRDIATGVRESARFYVELHKLGVNIQCFDVGGGLGVDYEGTRSQSDCSVNYGLNE
                     YANNIIWAIGDACEENGLPHPTVITESGRAVTAHHTVLVSNIIGVERNEYTVPTAPAE
                     DAPRALQSMWETWQEMHEPGTRRSLREWLHDSQMDLHDIHIGYSSGTFSLQERAWAEQ
                     LYLSMCHEVQKQLDPQNRAHRPIIDELQERMADKMYVNFSLFQSMPDAWGIDQLFPVL
                     PLEGLDQVPERRAVLLDITCDSDGAIDHYIDGDGIATTMPMPEYDPENPPMLGFFMVG
                     AYQEILGNMHNLFGDTEAVDVFVFPDGSVEVELSDEGDTVADMLQYVQLDPKTLLTQF
                     RDQVKKTDLDAELQQQFLEEFEAGLYGYTYLEDE"
     gene            complement(8558..8689)
                     /gene="yqgB"
                     /locus_tag="IRB70_002618"
     CDS             complement(8558..8689)
                     /gene="yqgB"
                     /locus_tag="IRB70_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417414.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response protein YqgB"
                     /protein_id="HBC0632517.1"
                     /translation="MKKKPVAQLERQHSLLENPCAYGLLSQFQAAIVVNCFTLNKII"
     gene            8825..9040
                     /locus_tag="IRB70_002619"
     CDS             8825..9040
                     /locus_tag="IRB70_002619"
                     /inference="COORDINATES: protein motif:HMM:NF037550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632518.1"
                     /translation="MGITSAGMQSRDAECGERIFTRTVRQVKQQTTVHYFVSPPRPPV
                     KTNPQAKTLFSTRLEVATRKKRRVLFI"
     gene            9344..10498
                     /gene="metK"
                     /locus_tag="IRB70_002620"
     CDS             9344..10498
                     /gene="metK"
                     /locus_tag="IRB70_002620"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBC0632519.1"
                     /translation="MAKHLFTSESVSEGHPDKIADQISDAVLDAILEQDPKARVACET
                     YVKTGMVLVGGEITTSAWVDIEEITRNTVREIGYVHSDMGFDANSCAVLSAIGKQSPD
                     INQGVDRADPLEQGAGDQGLMFGYATNETDVLMPAPITYAHRLVQRQAEVRKNGTLPW
                     LRPDAKSQVTFQYDDGKIVGIDAVVLSTQHSEEIDQKSLQEAVMEEIIKPILPAEWLT
                     SATKFFINPTGRFVIGGPMGDCGLTGRKIIVDTYGGMARHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLADRCEIQVSYAIGVAEPTSIMVETFGTEKVPSEQLTLLVREFF
                     DLRPYGLIQMLDLLHPIYKETAAYGHFGREHFPWEKTDKAQLLRDAAGLK"
     gene            10934..12328
                     /gene="galP"
                     /locus_tag="IRB70_002621"
     CDS             10934..12328
                     /gene="galP"
                     /locus_tag="IRB70_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose/proton symporter"
                     /protein_id="HBC0632520.1"
                     /translation="MPDAKKQGRSNKAMTFFVCFLAALAGLLFGLDIGVIAGALPFIA
                     DEFQITSHTQEWVVSSMMFGAAVGAVGSGWLSFKLGRKKSLMIGAILFVAGSLFSAAA
                     PNVEVLILSRVLLGLAVGVASYTAPLYLSEIAPEKIRGSMISMYQLMITIGILGAYLS
                     DTAFSYTGAWRWMLGVIIIPAILLLIGVFFLPDSPRWFAAKRRFVDAERVLLRLRDTS
                     AEAKRELDEIRESLQVKQSGWALFKENSNFRRAVFLGVLLQVMQQFTGMNVIMYYAPK
                     IFELAGYTNTTEQMWGTVIVGLTNVLATFIAIGLVDRWGRKPTLTLGFLVMAAGMGVL
                     GTMMHIGIHSPSAQYFAIAMLLMFIVGFAMSAGPLIWVLCSEIQPLKGRDFGITCSTA
                     TNWIANMIVGATFLTMLNTLGNANTFWVYAALNVLFILLTLWLVPETKHVSLEHIERN
                     LMKGRKLREIGAHD"
     gene            12405..12902
                     /locus_tag="IRB70_002622"
     CDS             12405..12902
                     /locus_tag="IRB70_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family zinc-dependent metalloprotease"
                     /protein_id="HBC0632521.1"
                     /translation="MKTSRLPIAIQQAVMRRLREKLAQANLKLGRNYPEPKLSYTQRG
                     TSAGTAWLESYEIRLNPVLLLENSEAFIEEVVPHELAHLLVWKHFGRVAPHGKEWKWM
                     MESVLGVPARRTHQFELQSVRRNTFPYRCKCQEHQLTVRRHNRVVRGEAVYRCVHCGE
                     QLVAK"
     gene            12997..13704
                     /gene="endA"
                     /locus_tag="IRB70_002623"
     CDS             12997..13704
                     /gene="endA"
                     /locus_tag="IRB70_002623"
                     /EC_number="3.1.21.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease I"
                     /protein_id="HBC0632522.1"
                     /translation="MYRYLSIAAVVLSTAFSGPALAEGINSFSQAKAAAVKVHADAPG
                     TFYCGCKINWQGKKGVVDLQSCGYQVRKNENRASRVEWEHVVPAWQFGHQRQCWQDGG
                     RKNCAKDPVYRKMESDMHNLQPSVGEVNGDRGNFMYSQWNGGEGQYGQCAMKVDFKEK
                     VAEPPARARGAIARTYFYMRDQYNLTLSRQQTQLFNAWDKMYPVTDWECERDERIAKV
                     QGNHNPYVQRACQARKS"
     gene            13784..14515
                     /gene="rsmE"
                     /locus_tag="IRB70_002624"
     CDS             13784..14515
                     /gene="rsmE"
                     /locus_tag="IRB70_002624"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003853382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBC0632523.1"
                     /translation="MRIPRIYHPEPLTSHSHIALCEDAANHIGRVLRMGPGQALQLFD
                     GSNQVFDAEITSASKKSVEVKVLEGQIDDRESPLHIHLGQVMSRGEKMEFTIQKSIEL
                     GVSLITPLFSERCGVKLDSERLNKKLQQWQKIAIAACEQCGRNRVPEIRPAMDLEAWC
                     AEQDEGLKLNLHPRASNSINTLPLPVERVRLLIGPEGGLSADEIAMTARYQFTDILLG
                     PRVLRTETTALTAITALQVRFGDLG"
     gene            14528..15478
                     /gene="gshB"
                     /locus_tag="IRB70_002625"
     CDS             14528..15478
                     /gene="gshB"
                     /locus_tag="IRB70_002625"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione synthase"
                     /protein_id="HBC0632524.1"
                     /translation="MIKLGIVMDPIANINIKKDSSFAMLLEAQRRGYELHYMEMADLY
                     LINGEARARTRTLSVEQNYDKWYEFTGEQDLPLADLDVILMRKDPPFDTEFIYSTYIL
                     ERAEDKGTLIVNKPQSLRDCNEKLFTAWFSDLTPETLVTRNKAQLKAFWEKHSDIILK
                     PLDGMGGASIFRVKEGDPNLGVIAETLTEHGTRYCMAQNYLPAIKDGDKRVLVVDGEP
                     VPYCLARIPQGGETRGNLAAGGRGEPRPLTESDWKIARQIGPTLKEKGLIFVGLDIIG
                     DRLTEINVTSPTCIREIEAEFPVSITGMLMDAIEARLQQQ"
     gene            15587..16150
                     /locus_tag="IRB70_002626"
     CDS             15587..16150
                     /locus_tag="IRB70_002626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005228750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgE/AlgH family protein"
                     /protein_id="HBC0632525.1"
                     /translation="MNLQHHFLIAMPALQDPIFRRSVVYICEHNTNGAMGIIVNKPLE
                     NLKIEGILEKLKITPEPRDESIRLDKPVMLGGPLAEDRGFILHTPPSNFASSIRISDN
                     TVMTTSRDVLETLGTDKQPSDVLVALGYASWEKGQLEQEILDNAWLTAPADLNILFKT
                     PIADRWREAAKLIGVDILTMPGVAGHA"
     gene            16150..16566
                     /gene="ruvX"
                     /locus_tag="IRB70_002627"
     CDS             16150..16566
                     /gene="ruvX"
                     /locus_tag="IRB70_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBC0632526.1"
                     /translation="MSGTLLAFDFGTKSIGVAVGQRITGTARPLPAIKAQDGTPDWNI
                     IERLLKEWQPDEIIVGLPLNMDGTEQPLTARARKFANRIHGRFGVEVKLHDERLSTVE
                     ARSGLFEQGGYRALNKGKVDSASAVIILESYFEQGY"
     gene            complement(16740..17720)
                     /locus_tag="IRB70_002628"
     CDS             complement(16740..17720)
                     /locus_tag="IRB70_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV pilus twitching motility protein PilT"
                     /protein_id="HBC0632527.1"
                     /translation="MNMEEIVALSVKHNVSDLHLCSAWPARWRIRGRMEAAPFDALDV
                     EELLREWLDDDQRTILLENGQLDFAVSLAENQRLRGSAFAQRQGISLALRLLPSHCPQ
                     LEQLGAPPVLPELLKSENGLILVTGATGSGKSTTLAAMVGYLNQHADAHILTLEDPVE
                     YLYTSQRCLIQQREIGLHCMTFASGLRAALREDPDVILLGELRDSETIRLALTAAETG
                     HLVLATLHTRGAAQAVERLVDSFPAQEKDPVRNQLAGSLRAVLSQKLEVDKQEGRVAL
                     FELLINTPAVGNLIREGKTHQLPHVIQTGQQVGMITFQQSYQQRVKEGRL"
     gene            17738..18442
                     /gene="yggS"
                     /locus_tag="IRB70_002629"
     CDS             17738..18442
                     /gene="yggS"
                     /locus_tag="IRB70_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate homeostasis protein"
                     /protein_id="HBC0632528.1"
                     /translation="MNDIAHNLAQVRDKISAAATRCGRSPEEITLLAVSKTKPASAIA
                     EAIDAGQRQFGENYVQEGVDKIRHFQELGVTGLEWHFIGPLQSNKSRLVAEHFDWCHT
                     IDRLRIATRLNDQRPAELPPLNVLIQINISDENSKSGIQLAELDELAAAVAELPRLRL
                     RGLMAIPAPESEYVRQFEVARQMAVAFAGLKTRYPHIDTLSLGMSDDMEAAIAAGSTM
                     VRIGTAIFGARDYSKK"
     gene            18460..19026
                     /gene="yggT"
                     /locus_tag="IRB70_002630"
     CDS             18460..19026
                     /gene="yggT"
                     /locus_tag="IRB70_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmotic shock tolerance protein YggT"
                     /protein_id="HBC0632529.1"
                     /translation="MNTLTFLLSTVIELYTMVLLLRIWMQWAHCDFYNPFSQFVVKVT
                     QPIIGPLRRVIPAMGPIDSASLLVAYILSFIKAIVLFKVVTFLPIIWIAGLLILLKTI
                     GLLIFWVLLVMAIMSWVSQGRSPIEYVLIQLADPLLRPIRRLLPAMGGIDFSPMILVL
                     LLYVINMGVAEVLQATGNMLLPGLWMAL"
     gene            19023..19313
                     /locus_tag="IRB70_002631"
     CDS             19023..19313
                     /locus_tag="IRB70_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417428.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggU family protein"
                     /protein_id="HBC0632530.1"
                     /translation="MSAVTVNDDGLVLRLYIQPKASRDSIVGLHGDEVKVAITAPPVD
                     GQANSHLVKFLGKQFRVAKSQVVIEKGELGRHKQIKIINPQQIPPEIAALIN"
     gene            19321..19914
                     /locus_tag="IRB70_002632"
     CDS             19321..19914
                     /locus_tag="IRB70_002632"
                     /EC_number="3.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708719.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XTP/dITP diphosphatase"
                     /protein_id="HBC0632531.1"
                     /translation="MQKVVLATGNAGKVRELASLLSDFGLDIVAQTDLGVDSAEETGL
                     TFIENAILKARHAAKVTGLPAIADDSGLAVDALGGAPGIYSARYSGEDATDQKNLQKL
                     LETMKDVPDDQRQARFHCVLVYLRHAEDPTPLVCHGSWPGVITREPAGTGGFGYDPIF
                     FVPSEGKTAAELTREEKSAISHRGQALKLLLDALRNG"
     gene            19907..21043
                     /gene="hemW"
                     /locus_tag="IRB70_002633"
     CDS             19907..21043
                     /gene="hemW"
                     /locus_tag="IRB70_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM family heme chaperone HemW"
                     /protein_id="HBC0632532.1"
                     /translation="MVKLPPLSLYIHIPWCVQKCPYCDFNSHALKGEVPHDDYVQHLL
                     NDLNNDVAYAQGREVKTIFIGGGTPSLLSGPAMQTLLDGIRARLPLAADAEITMEANP
                     GTVEADRFVDYQRAGVNRISIGVQSFSEEKLKRLGRIHGPQEAKRAANLASGLGLRSF
                     NLDLMHGLPDQSLEEALGDLRQAIELNPPHLSWYQLTIEPNTLFGSRPPVLPDDDALW
                     DIFEQGHQLLTAAGYQQYETSAYAKPGYQCQHNLNYWRFGDYIGIGCGAHGKVTFLDG
                     RILRTTKTRHPRGFMQGRYLESQRDVEAADKPFEFFMNRFRLLEAAPRVEFSQYTGLS
                     EEVIRPQLDEAIAQGYLTECADYWQITEHGKLFLNSLLELFLAE"
     gene            complement(21112..22119)
                     /locus_tag="IRB70_002634"
     CDS             complement(21112..22119)
                     /locus_tag="IRB70_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1202 family protein"
                     /protein_id="HBC0632533.1"
                     /translation="MKKQWIVGTALFMLMTGNVWADGEPPTENILKDQFKKQYHGILK
                     LDVITLKNLDAKGNQATWSAEGDVSSSDDLYTWVGQLADYELLEQTWTKDKPVKFSAM
                     LTSKGTPASGWSVNFYSFQAAASDRGRVVDDIKTNNKYLIVNSEDFNYRFSQLESALN
                     NQNNSIPALKKDVKALDKQMVAAQKAADAYWGKDANGKQMTREDAFKKIHQQRDDFNK
                     QNDSEAFAVKYDKEVYQPAIAACHKQSEECYEVPIQQKRDFDINEQRRQTFLQSQKLS
                     RKLQDDWITLEKGQYPLTMKVSEINSKKVAILMKIDDINQANERWKKDTEQLRRNGVI
                     K"
     gene            complement(22236..23282)
                     /gene="ansB"
                     /locus_tag="IRB70_002635"
     CDS             complement(22236..23282)
                     /gene="ansB"
                     /locus_tag="IRB70_002635"
                     /EC_number="3.5.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparaginase 2"
                     /protein_id="HBC0632534.1"
                     /translation="MEFFKKTALAALVMGFSGAALALPNITILATGGTIAGGGDSATK
                     SNYTAGKVGVENLVNAVPQLKDIANVKGEQVVNIGSQDMNDDVWLTLAKKINTDCDKT
                     DGFVITHGTDTMEETAYFLDLTVKCDKPVVMVGAMRPSTSMSADGPFNLYNAVVTAAD
                     KASANRGVLVVMNDTVLDGRDVTKTNTTDVATFKSVNYGPLGYIHNGKIDYQRTPARK
                     HTSDTPFDVSKLNELPKVGIVYNYANASDLPAKALVDAGYDGIVSAGVGNGNLYKTVF
                     DTLATAAKNGTAVVRSSRVPTGATTQDAEVDDAKYGFVASGMLNPQKARVLLQLALTQ
                     TKDPQQIQQIFNQY"
     gene            complement(23458..24177)
                     /locus_tag="IRB70_002636"
     CDS             complement(23458..24177)
                     /locus_tag="IRB70_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2884 domain-containing protein"
                     /protein_id="HBC0632535.1"
                     /translation="MMRKMLLAAALSVTAMTAHADYQCSVTPRDDVIVSPQTVQVKGE
                     NGNLVITPDGNVMYNGKQYSLNAAQREQAKDYQAELRSTLPWIDEGAKSRVEKARIAL
                     DKIIVQEMGESSKMRSRLTKLDAQLKEQMNRIIETRSDGLTFHYKAIDQVRAEGQQLV
                     NQAMGGILQDSINEMGAKAVLKSGGNPLQNVLGSLGGLQSSIQTEWKKQEKDFQQFGK
                     DVCSRVVTLEDSRKALVGNLK"
     gene            complement(24361..24687)
                     /locus_tag="IRB70_002637"
     CDS             complement(24361..24687)
                     /locus_tag="IRB70_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417434.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggL family protein"
                     /protein_id="HBC0632536.1"
                     /translation="MAKNRSRRLRKKMHIDEFQELGFSVAWRFPEGTSEEQIDKTVDD
                     FINEVIEPNKLAFDGSGYLAWEGLICMQEIGKCTEEHQAIVRKWLEERKLEEVRTSEL
                     FDVWWD"
     gene            complement(24687..25406)
                     /gene="trmB"
                     /locus_tag="IRB70_002638"
     CDS             complement(24687..25406)
                     /gene="trmB"
                     /locus_tag="IRB70_002638"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBC0632537.1"
                     /translation="MKNDVISPEFDENGRPLRRIRSFVRRQGRLTKGQEHALENYWPV
                     MGVEFSEDMLDFPALFGREAPVTLEIGFGMGASLVAMAKDRPEQDFLGIEVHSPGVGA
                     CLSSAHEEGLSNLRVMCHDAVEVLHKMIPDNSLRMVQLFFPDPWHKARHNKRRIVQVP
                     FAELVKSKLQLGGIFHMATDWEPYAEHMLEVMSSIDGYKNLSESNDYVPRPASRPVTK
                     FEQRGHRLGHGVWDLMFERVK"
     gene            25567..26619
                     /gene="mutY"
                     /locus_tag="IRB70_002639"
     CDS             25567..26619
                     /gene="mutY"
                     /locus_tag="IRB70_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBC0632538.1"
                     /translation="MQASQFSAQVLDWYDKYGRKTLPWQIDKTPYKVWLSEVMLQQTQ
                     VATVIPYFERFMVRFPTVTDLANAPLDEVLHLWTGLGYYARARNLHKAAQQVAALHGG
                     KFPETFEEVAALPGVGRSTAGAILSLSLGKHFPILDGNVKRVLARCYAVSGWPGKKEV
                     ENKLWSLSEQVTPAVGVERFNQAMMDLGAMICTRSKPKCSLCPLQNGCIAAANNSWSL
                     YPGKKPKQTLPERTGYFLLLQHEDEVLLAQRPPSGLWGGLYCFPQFADEESLRQWLAQ
                     RQIAADNLTQLTAFRHTFSHFHLDIVPMWLPVSSFTGCMDEDNALWYNLAQPPSVGLA
                     APVERLLQQLRTGAPV"
     gene            26647..26922
                     /locus_tag="IRB70_002640"
     CDS             26647..26922
                     /locus_tag="IRB70_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative damage protection protein"
                     /protein_id="HBC0632539.1"
                     /translation="MSRTIFCTFLQREAEGQDFQLYPGELGKRIYNEISKEAWAQWQH
                     KQTMLINEKKLNMMNAEHRKLLEQEMVNFLFEGKEVHIEGFTPEDKK"
     gene            26987..28066
                     /gene="mltC"
                     /locus_tag="IRB70_002641"
     CDS             26987..28066
                     /gene="mltC"
                     /locus_tag="IRB70_002641"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417438.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane-bound lytic murein transglycosylase
                     MltC"
                     /protein_id="HBC0632540.1"
                     /translation="MKKYLALALIAPLLISCSTTKKGDTYNEAWVKDTNGFDILMGQF
                     AHNIENIWGFKEVVIAGPKDYVKYTDQYQTRSHINFDDGTITIETIAGTEPAAHLRRA
                     IIKTLLMGDDPSSVDLYSDVDDITISKEPFLYGQVVDNTGQPIRWEGRASNFADYLLK
                     NRLKSRSNGLRIIYSVTINMVPNHLDKRAHKYLGMVRQASRKYGVDESLILAIMQTES
                     SFNPYAVSRSDALGLMQVVQHTAGKDVFRSQGKSGTPSRSFLFDPASNIDTGTAYLAM
                     LNNVYLGGIDNPTSRRYAVITAYNGGAGSVLRVFSNDKIQAANIINTMTPGDVYQTLT
                     TRHPSAESRRYLYKVNTAQKSYRRR"
     gene            28268..29524
                     /gene="nupG"
                     /locus_tag="IRB70_002642"
     CDS             28268..29524
                     /gene="nupG"
                     /locus_tag="IRB70_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311867.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupG"
                     /protein_id="HBC0632541.1"
                     /translation="MNLKLQLKILSFLQFCLWGSWLTTLGSYMFVTLKFDGASIGAVY
                     SSLGIAAVFMPALLGIVADKWLSAKWVYAICHTIGAITLFMAAEVTTPEAMFLVILIN
                     SFAYMPTLGLINTISYYRLQNAGMDIVTDFPPIRIWGTIGFIMAMWVVSLSGFELSHM
                     QLYIGAALSAILVLFTLTLPHIPVAKQQANQSWTTLLGLDAFALFKNKRMAIFFIFSM
                     LLGAELQITNMFGNTFLHSFDKDPMFASSFIVQHASIIMSISQISETLFILTIPFFLS
                     RYGIKNVMMISIVAWILRFALFAYGDPTPFGTVLLVLSMIVYGCAFDFFNISGSVFVE
                     KEVSPAIRASAQGMFLMMTNGFGCILGGIVSGKVVEMYTQNGTTDWQTVWLIFAGYSV
                     VLAFAFMAMFKYKHVRVPTGTQTVSH"
     gene            complement(29573..31708)
                     /gene="speC"
                     /locus_tag="IRB70_002643"
     CDS             complement(29573..31708)
                     /gene="speC"
                     /locus_tag="IRB70_002643"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311868.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase"
                     /protein_id="HBC0632542.1"
                     /translation="MKSMNIAASSELVSRLSTHRRVVALGDTDFTDVAAVVITAADSR
                     SGILALLKRTGFHLPVFLYSEHAVELPAGVTAVINGNEQQWLELESAACQYEENLLPP
                     FYDTLTQYVEMGNSTFACPGHQHGAFFKKHPAGRHFYDFFGENIFRADMCNADVKLGD
                     LLIHEGSAKDAQKFAAKVFHADKTYFVLNGTSAANKVVTNALLTRGDLVLFDRNNHKS
                     NHHGALIQAGATPVYLEASRNPFGFIGGIDAHCFNEEYLRQQIRDVAPEKADLPRPFR
                     LAIIQLGTYDGTVYNARQVIDTVGHLCDYILFDSAWVGYEQFIPMMADSSPLLLELNE
                     NDPGIFVTQSVHKQQAGFSQTSQIHKKDNHIRGQARFCPHKRLNNAFMLHASTSPFYP
                     LFAALDVNAKIHEGESGRRLWAECVELGIESRKAILARCKLFRPFIPPVVDGKLWQDY
                     PTSVLASDRRFFSFEPGANWHGFEGYAADQYFVDPCKLLLTTPGIDAETGEYSDFGVP
                     ATILAHYLRENGIVPEKCDLNSILFLLTPAESHEKLAQLVAMLAQFEQHIEDDSPLAE
                     VLPSVYNKYPVRYRDYTLRQLCQEMHDLYVSFDVKDLQKAMFRQQSFPSVVMNPQDAH
                     SAYIRGEVELVRIRDAEGRIAAEGALPYPPGVLCVVPGEVWGGAVQRYFLALEEGVNL
                     LPGFSPELQGVYSETDADGMKRLYGYVLK"
     gene            32107..32814
                     /locus_tag="IRB70_002644"
     CDS             32107..32814
                     /locus_tag="IRB70_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBC0632543.1"
                     /translation="MVIGPFINASAVLLGGVFGALLSQRLPERIRVSMTSIFGLASLG
                     IGILLVVKCANLPAMVLATLLGALIGEICLLEKGVNTVVAKAHNLFHHSRKKPAHESF
                     IQNFVAIIVLFCASGTGIFGAMNEGMTGDPSILIAKSFLDFFTAMIFACSLGIAVSVI
                     SIPLLIIQLTLAWAAALILPLTTPSMMADFSAVGGLLLLATGLRICGIKMFPVVNMLP
                     ALLLAMPLSAAWTAWFA"
     gene            32920..32995
                     /locus_tag="IRB70_002645"
     tRNA            32920..32995
                     /locus_tag="IRB70_002645"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:32953..32955,aa:Phe,seq:gaa)
     gene            33193..34458
                     /locus_tag="IRB70_002646"
     CDS             33193..34458
                     /locus_tag="IRB70_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
                     /protein_id="HBC0632544.1"
                     /translation="MALTDAKIRAAKPTDKAYKLTDGAGMFLLVHPNGSRYWRLRYRI
                     LGKEKTLALGVYPEVSLSEARTKRDEARKLISEGVDPCEQKRAKKVVPDLQLSFEHIA
                     RRWHASNKQWAQSHSDKVLKSLETHVFPFIGNRDITTLSTPDLLIPVRAAEVKQIYEI
                     ASRLQQRISAVMRYAVQSGIIRYNPALDMAGALTTVKRQHRPALDLSRLPELLSRIDG
                     YKGQPVTRLAVMLNLLVFIRSSELRYARWSEIDIDNAMWTIPAEREPLPGVKFSYRGS
                     KMRTPHLVPLSQQAVAILAELQTWAGENGLIFTGAHDPRKPISENTVNKALRVMGYDT
                     TKEVCGHGFRAMACSALIESGLWSRDAVERQMSHQERNGVRAAYIHKAEHLEERRLML
                     QWWADFLDANREECISPFEYAKVNNPLKR"
     gene            34714..35757
                     /locus_tag="IRB70_002647"
     CDS             34714..35757
                     /locus_tag="IRB70_002647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBC0632545.1"
                     /translation="MTGKLRFEVNDNQGCFIFPETWFGSLLDEFEELIDAYDADEISE
                     TSYINKLRRLARQENDFIDVHAHLAYVFLEQNAPRKALNAALKGLAIGNRLIPEGFSG
                     RIIWIHPDNRPFLRALYAAILANAHLQRHQDAIMLIEKILDYNPEDNHGARWLLGPEL
                     LRTGAHEQARHILQEHADEFSPYWYELGLLHFLNGELVKAATAFRRGFAANTYIAEIL
                     CGNLHPFPLAVWHNFSGGPDTAEDYYATYHPLWGQYPEALLFVNWLYNHSSVLHERAE
                     IIKCAEMLMQEDDFEICESILRQQEKLRERIDETLSEKIVQKCRNMNGEYIWPWILPF
                     SAAGMKHTGIQYQ"
BASE COUNT         8886 a         9459 c         9020 g         8861 t
ORIGIN      
        1 actccacgag caaaaataac aaaatattga ataacaacaa catgaaataa gcttttaaaa
       61 agtcaattat aaatctgtta agtaaactac aaaatcaaca aattattcat cactatattt
      121 gtgatacaca tctctatttt cttattgaat gctcgaaaac atacttatta cgtttattat
      181 tttttcgctc atccccttta taaattctga attatcggct gttgtctgtt ttctcatcac
      241 ctcatgtgac atattcccca ctttactcaa ggaagattca tatgaaagca cctgtttcat
      301 taacctcatt tcgcccacaa aaatctcttg ctatcgccat tggcgtgctt gccgtggttg
      361 tgctgccatt tctctcgtat tacaccgtta atgaaggtga acgcggcatt ttgctgcgct
      421 acggaaaaat cgtaaaagtt gccgagccgg ggctgggttt taagatccct tttatggaaa
      481 gcgtagagaa aatttccacg cgtaatcagg ctgtggtcta tcagggatta caggcctaca
      541 gccgcgacca gcaaccggca caaatgacag tatcagtcag cttccacatt aaaccttcag
      601 aagcaggcgc ggtttatacc acctacaaca ccattgaagc attaaaagat cgtctgattg
      661 tccgtcagtt gccaactcaa ctggagaacg ttttcggaca atataccgcc atcagcgccg
      721 tacaggatcg tacaaaactg gttcaggatc tgcaaaatgc catgcgcaaa gccgttgttg
      781 ggccagtggt aattgacggg gtccagattg aaaatattga tttttctgac gcttatgaaa
      841 agtcgattga agaccgaatg aaagcagaag tcgccattgc cacgcgtaag caaaatctgg
      901 aaacggagaa aatccaggcg caaatagcgg taactcaggc ccaggcggaa gcagacagta
      961 aactagcggc agccaaagca gaagcggaaa ctattcgcgt aagaggcgcg gcagaggctg
     1021 aaactattcg tttaaaaagt gcggctgaag cagaagctat ccgcctgcgc ggtgaagctc
     1081 tgcgggagaa tcccggactt gttgccctca ccactgctga gcgttgggac ggtaaactgc
     1141 ccgataccat gatccccggc agcacagttc cgtttatctc tactaagtaa aaaagggccg
     1201 ctttcgcggc ccttgagact gatagcaaag acaaaactgc ctgatgcgct acgcttatca
     1261 ggcctacata cttcctgcaa tatgttgaat ttgcaaaatc ttgtaggacg gataaggcgt
     1321 tcacgccgca tccggcataa acaacgcgca ctttgccaac aatctgaagg gccgcatttg
     1381 cggcccttct cacaaagcat cttaccgatt acagcagcgc ttttgctttc gcaacaacgt
     1441 tgtcaacggt gaagccgaac tcttcaaaca gctgctctgc cggagcagat tcaccgaagg
     1501 tggtcatgcc gacgatagca ccgttcaggc caacatactt gtaccagtag tcagcaatgc
     1561 cagcttccac cgcaacacga gcggtaaccg ctttcggcag tacggattca cggtaagccg
     1621 cgtcctgctt gtcgaatgcg tcggtagacg gcatggaaac cacgcgcgct ttcacgcctt
     1681 cggcagtcag tttttcgtag gcggcaacag ccagttcaac ttcagaaccg gtcgcgatga
     1741 agatcagttc cggctgacca gcacagtctt tcagcacata accaccgcgc gcgatgtttg
     1801 ccagctgctc ttcagtacgt tcctgctgcg ccaggttctg acgggagagg ataagcgcag
     1861 tcgggccgtc ctgacgctca acgccgtatt tccacgctac tgcggattca acctggtcac
     1921 acggacgcca tgtagacatg ttcggggtca cgcgcagaga agcgatctgt tctaccggct
     1981 ggtgagtcgg gccatcttcg cccagaccga tggagtcgtg ggtgtaaacc atcacctgac
     2041 gctgtttcat cagcgcagcc atacgtacgg cattacgtgc gtattccacg aacatcagga
     2101 aggttgaggt atacggcagg aaaccaccgt gcagggagat accgttggca atcgcagtca
     2161 taccgaattc acgtacaccg tagtggatgt agttacccgc agcatcttcg ttgattgctt
     2221 tagaaccaga ccacagggtc aggttagacg gcgccaggtc tgcagaaccg ccgaggaatt
     2281 ccggcaacag cggcccgaac gcttcgatag cattctgaga cgctttacgg ctggcgatct
     2341 tcgccggatt agcctgaagt ttagcgatga actctttcgc tttggcgtcg aagtcagacg
     2401 gcatttcgcc tttcatacgg cgggtaaatt cagcagcttc ctgcggataa gctttcgcgt
     2461 aagcagcgaa tttctcgttc catgcgaatt ctttcgcctg gcctgcttct ttcgcatccc
     2521 actgagcata gatttcagac gggatttcga acggcgcgta tttccagccc agctgttcgc
     2581 gggtcagggc aatttcagcg tcgcccagcg gcgcaccgtg ggagtcgtgg gtaccggctt
     2641 tgttcgggga accgaaaccg atgatggttt tgcacatcag cagggacggt ttgtcagtca
     2701 ctgcgcgcgc ttcttctact gcgcgtttga tggatgccgc gtcatgaccg tcgatatcgc
     2761 gaataacgtg ccagccgtaa gcttcgaaac gcattgcggt gtcgtcggta aaccagcctt
     2821 caacgtgacc atcgatagaa ataccgttgt catcgtagaa cgcaatcagt ttacccagct
     2881 tcagcgtacc cgccagagag caaacttcgt gggagatgcc ttccatcatg cagccgtcgc
     2941 ccatgaaggc gtaggtgtag tggtcgacga tgtcgtggcc cggacggtta aactgcgccg
     3001 ccagcgtttt ttctgcaatc gccataccga ctgcgttggc aataccctga cccagcggac
     3061 cggtggtggt ttctacacct gcggtgtaac ccacttccgg gtgacccgga gttttagagt
     3121 gcagctgacg gaagtttttc agttcttcca tcggcagatc gtaaccggtg aggtgcagca
     3181 ggctgtagat cagcatggag ccgtggccgt tggacagcac gaagcggtca cggtcagccc
     3241 aggacggatt ctgcgggttg tgtttcagga aatcacgcca caggacttcg gcaatgtcag
     3301 ccatacccat aggggcaccc gggtgaccgg atttggcttt ctgtactgcg tccatgctca
     3361 gcgcacgaat agcattggca agctctttac gtgaggacat tttgactcca gatcggatga
     3421 tgaagggcac gcccttaacg acttgacgac agcgcgtttt gggctacgcc ggaaaatttg
     3481 ccaacaattt accgcaagcc gctcgtcatg tacatggaac atccttttgc cgcttcagaa
     3541 atctctggat catgctcgca tgttgcgcaa tccactcgcc cgtccgctgc gcttttcctt
     3601 atactgagac tgagcgtcga ttcacctgca aacggcgcat ttttagaata atcctgacct
     3661 tgtgcggaag agaaaacatg aaaattcgcg ccttattggt agcaatgagc gtggctacgg
     3721 tgctgaccgg ttgccagaat atggactcca gtggactgct ctcatcagga gcggaagctt
     3781 ttcaggctta cagtttgagt gatgcgcagg tgaaaaaact gagcgatcag gcatgccagg
     3841 agatggacag caaagcgacg attgcgccag ccaatagcga atatgctaga cgtctgacga
     3901 caatttctcg cgcgttaggc gataacatca acggtcagcc ggtgaattac aaagtgtata
     3961 tggcgaagga tgtgaacgcc tttgcaatgg ctaacggctg tatccgcgtc tatagcgggc
     4021 tgatggatat gatgacggat aacgaagtcg aagcggtgct cggtcacgaa atggggcacg
     4081 tggcattagg ccatgtgaag aaaggaatgc aggtagcact tggtacaaac gcaattcgcg
     4141 ttgcggcggc ctctgcaggc ggaattgtcg gcagtttgtc acaatcacaa ctgggagacc
     4201 tgggcgaaaa gctagtcaat tcgcaattta cccaacgtca ggaatcagag gccgatgatt
     4261 actcctacga tttgctgcgc caacgcggta tcagcccggc aggtcttgcc accagctttg
     4321 aaaaactggc gaaactggaa gaaggccgcc aaagctcaat gtttgacgac catcctgcat
     4381 ccgccgaacg cgcccagcat attcgcgatc gtatgagcgc ggatggagtt aagtaaagcc
     4441 aggtagtgcc gaacgtaggt cggataaggc gttcacgccg catctgacaa gaatggcaca
     4501 tttgttactc cgtgcgcatt gccggatgcg atgctggcgt atcttatccg gcctacgggt
     4561 gccgagtgta ggtcggataa ggcgttcacg ccgcatccga cattaatggc acatcacccg
     4621 cgcgcctctt atctggcgct tactcgccct ttttcgccgc ctggatatac agcatctcca
     4681 gcgccagcgt cgccgcagcc agagcggtga tttccgactg atcgtatgcc ggagccacct
     4741 ccactacgtc catcccaacg atgttgagat ctttcaagcc gcgtaccagt ttaatggcgc
     4801 gatcggaggt caggccgcca attaccggcg taccggtgcc tggtgcaaaa gcaggatcca
     4861 ggcagtcgat atcaaaggtc aggtaaaccg gcatatcacc cacaatctgt ttcacctggg
     4921 cgataatgtc atccacgctg cgatcgttca cctggcaggc gtccagcacg gtaaagccgt
     4981 tgtctttatc aaactcggta cgaataccaa tctgcacaga atgattcggg tcgatcagac
     5041 cttctttcgg cgcggtatag aacatggtgc cgtggtcaaa ttcacaaccg ttagcgtagg
     5101 tatcggtgtg ggcatcaaag tgtaccaacg ccattttgcc gaaatgcttc gcatgagcgc
     5161 gcagcagcgg cagcgtaaca aagtggtcac caccgaagga gagcatacgc ttaccggcag
     5221 ccagcagctt ctcggcgtgc gcctgcagct tctcgctcat ctcacgggca tctccgaagg
     5281 catataccag atcgccgcag tccacgacgt tcaggcgctc acgcatgtcg aaattccacg
     5341 ggaagcgatt gtgttcccag gccagattcg tcgaaacctg acggatcgct gccggaccgt
     5401 ggcgaccacc cgcacgacca gaagtggcca tatcgaacgg cacgccagta atcacccagt
     5461 cagcatcgct gtcatatggc tggaagttca tcggcaggcg taaaaaacca aaggcgttgg
     5521 aaaccagtga gttatcgtat tgatgaccta aggtgctcat ggatggactc ctattacaaa
     5581 gtcgatataa aaaaaccctt ccgcgtcgtt aggcccgacg aggaagggtt ggatttgtga
     5641 aacacaagtt tgtgctaatt atcgccttaa atgggcgagg catcaagcga ggttgctatt
     5701 tccgacacgg tggcggcgca tagccattgt tatctgccgg aaaggcttgt ccagagcacg
     5761 gcggcagcgc gtttttcgcc gggccttgta attcaaaggc ggcaaagccg attacaccgg
     5821 tattacgcac atcgccttgc gccgaattgg ctgcgtagga atcagcaacg ttggcgaact
     5881 gaaaagccgc ttcggtatgt ttatctttgc ggaatccttt aatcgctaac gaatctccgg
     5941 cattcacaat ataaccgttg ttattcagcg aaccttgctt gccgttcagc acatccaggc
     6001 catcaaccgt agcaacgatc tcgtagttgg tgttacgact gtaattacgg acatataatt
     6061 gataattcat tccgactctg gcatggacaa tatagcgtgg ttcattattg gatgaatcat
     6121 aaacccgcgt aataggtaga gaattaaaat taccatcgcg aatagcatat tccagttcgt
     6181 taatacgaat gctataaacg cggtcgtagc cggaaggaac attagtcgaa taactaataa
     6241 cgatcatctc tgccggatcg cgccaggctc gttcagcaga tacgccctga accgttgagt
     6301 gcacatcccc accccaggcg gtgccgacat tgcctgatgc actgctatta tactgcgcat
     6361 tactggaaca accagccagc agcacgatta atgccaccaa cgcgctacgt actttccatt
     6421 ttttcataac cgttccctct gcatttaatt aatgcagcga ttgtagggag attatttaat
     6481 aagaaaagca gctaaattat ttttaagaat atataaaaag aaagcgggcc gatttacgta
     6541 aataaatcgc cccgccagca gaataatctt aattattcat cttcaagata ggtataaccg
     6601 tacaaacctg cctcgaactc ttccaggaac tgttgttgca gttcagcatc aagatcggtt
     6661 ttcttcacct gatcgcggaa ctgagttaac agcgttttcg gatcgagctg cacatattgc
     6721 agcatgtccg ccacggtatc gccttcgtca gacagttcta cctctacgct accatcaggg
     6781 aagacgaaca cgtcaaccgc ttcggtatca ccgaacaggt tgtgcatgtt gccgaggatc
     6841 tcctgatatg cgccgaccat aaagaaaccg agcatcggcg gattctccgg atcgtactcc
     6901 ggcataggca ttgtcgtggc aataccgtca ccatcaatat agtggtcgat agcaccgtct
     6961 gagtcacagg taatatccag cagcacagcg cggcgttccg gcacttgatc cagcccttcc
     7021 agcggcagaa ccgggaacaa ctggtcgatc ccccacgcat ccggcatcga ctggaacagc
     7081 gagaagttga cgtacatttt gtccgccata cgttcctgca gctcgtcgat aatcggacga
     7141 tgagcacggt tttgcggatc cagctgcttt tgcacttcat ggcacatgct caaataaagc
     7201 tgctcagccc atgcgcgttc ttgcaggcta aaggtgccgg aagagtagcc gatatgaatg
     7261 tcgtgcagat ccatctggct gtcgtgtaac cattcacgca gagaacggcg agttcccggt
     7321 tcgtgcattt cctgccaggt ttcccacatg ctttgcaggg cgcgcggtgc atcttctgca
     7381 ggcgcggtcg gcaccgtgta ttcgttacgt tccacgccga tgatattcga caccagcacg
     7441 gtgtgatgcg cagtcaccgc acgacccgat tcggtgatta ccgtcggatg tggcagacca
     7501 ttttcttcac acgcatcacc aatcgcccag atgatgttgt tggcgtattc attgaggccg
     7561 tagtttacgg agcagtcaga ctgagaacgg gtgccttcat agtccacgcc cagaccgccg
     7621 ccgacgtcga agcactgaat attgacgccc agcttgtgca gttccacata gaaacgcgcg
     7681 gattcacgaa cgcctgtcgc gatatcgcga atattcgcca tctgcgaacc gaggtggaag
     7741 tgcagcagtt gcaggctgtc gagacgcccg gcttcacgca gcgtttcaac cagttgcagt
     7801 acttgagtcg ccgccaggcc aaacttcgat ttttccccgc cggaggactg ccatttaccc
     7861 gagccctgcg aagccagacg tgcacgcacg cccagacgag gaacgacatt cagacgttct
     7921 gcttcatcca gcacaatggc aatttctgac atcttctcaa tgaccagata gaccttgtgg
     7981 cccatcttct cgccaattaa tgccaggcgg atatattcgc ggtccttata accgttgcag
     8041 acgatgacgc tacgggtcat gccagcatgt gccagcaccg ccatcaactc ggctttggaa
     8101 ccggcttcca ggcccagcgg ttcgcccgaa tgaatcaggg actcaatcac gcggcggtgc
     8161 tggttaactt tgatcggata aacgaggaag taatcgccgt tatagccgta ggattcccgc
     8221 gctcgtttga acgcggcgtt aatggaacgc aaacggtgct gcaggatctg tgggaaacag
     8281 aacagtgcag gcagacgctg accctgtgct tcgcgagttt tcactaactg cgcgagatcg
     8341 acgcgagctt ccgggacgtc cgggtccggg cacacgctga tgtggcccag ctcgttaacg
     8401 tcatagtagt tattgcccca ccaggcaata ttgtaagtac gcagcatctt gctggcttcc
     8461 tgggagctca ttgcaacctc ctgcatggag cgtagtacac cgtgttcgcc cgctgacgaa
     8521 ggcaaaccca tagacatgtc gtcagacata gcgaacctca aattatttta ttaagtgtaa
     8581 aacagttaac gactatcgca gcctggaact gcgataacaa cccataagca catggatttt
     8641 ccagcagtga atgctgacgc tccaactgcg caaccggttt ctttttcata acattattaa
     8701 gcacataacc gaacgtaagt gtgacagttc ggcgaaacca cgagaaaact cttgttttta
     8761 caagagcgcc cttgttcagt cctcagtagc tgtaaccagc tcttgaatcc tgagaagcgc
     8821 cgagatgggt ataacatcgg caggtatgca aagcagagat gcagagtgcg gggaacgaat
     8881 cttcaccaga acggtgagac aggttaagca gcagacaacg gttcattatt tcgtatcacc
     8941 tccacggccg cctgttaaga cgaacccaca agccaaaact ctgttttcaa cccggctgga
     9001 agtggcaaca cgaaagaaac gtcgtgtgct ttttatttaa gccgcgcgcc gcgttttata
     9061 ccccacaatg gcagaaaatt gcaaaagata aatacgcaga atgccagcat tgtcaggaaa
     9121 aatttccagc cacgttttta acagaatgag acacgattca aaaaaaagtg gaaattgggt
     9181 gaagaactga cctaaaatag ccatccagat gttaatccat ccataccgat taacactcag
     9241 actgccagtg tttttaacct gcagagtcgt ggtaggatcc gctaccacag aaaatccaca
     9301 caacagtttg agctaaccaa attctcttta ggtgatatta aatatggcaa aacacctttt
     9361 tacgtccgag tccgtctctg aagggcatcc tgacaaaatt gctgaccaaa tctctgatgc
     9421 cgttttagac gcgatcctcg aacaggatcc gaaagcacgc gttgcttgcg aaacctacgt
     9481 aaaaaccggc atggttttag ttggcggcga aatcaccacc agcgcctggg tagacatcga
     9541 agagatcacc cgtaataccg ttcgcgaaat tggctatgtg cattccgaca tgggctttga
     9601 cgctaactcc tgtgcggttc tgagcgccat cggtaaacag tctcctgaca tcaaccaggg
     9661 cgttgaccgt gccgatccgc tggaacaggg cgcgggcgac caggggctga tgtttggcta
     9721 cgcaactaat gaaaccgacg tgctgatgcc agcacctatc acttatgcac accgtctggt
     9781 acagcgtcag gctgaagtgc gtaaaaacgg cactctgccg tggctgcgcc cggacgcgaa
     9841 aagccaggtg actttccagt atgacgacgg caaaatcgtt ggcattgatg ctgtcgtgct
     9901 ttccactcag cactctgaag agatcgacca gaaatcgctg caagaagcgg taatggaaga
     9961 gatcatcaag ccgattctgc ccgctgaatg gctgacttct gccaccaaat tcttcatcaa
    10021 cccgaccggt cgtttcgtta tcggtggccc gatgggtgac tgcggtctga ctggtcgtaa
    10081 aatcatcgtt gatacctacg gcggcatggc gcgtcatggt ggcggtgcgt tctccggtaa
    10141 agatccatca aaagtggacc gttccgcagc ctacgcagca cgttatgtcg cgaaaaacat
    10201 tgttgctgct ggcctggccg atcgttgtga aattcaggtt tcctacgcaa tcggcgtggc
    10261 tgaaccgact tccatcatgg tagaaacttt cggtactgag aaagtgcctt ctgaacaact
    10321 gactctgctg gtacgtgaat tcttcgacct gcgcccatac ggtctgattc agatgctgga
    10381 tctgctgcac ccgatctaca aagaaaccgc agcatacggt cactttggtc gtgaacattt
    10441 cccgtgggaa aaaaccgaca aagcgcagct gctgcgtgat gctgccggtc tgaagtaatc
    10501 tttcttcacc tgctttcaaa ggccagcctc gcgctggcct ttttctttta cctcaccgca
    10561 gtggacaggc gttcacgccg catccggcaa aaaaccgccc gcacaataac atcattcttc
    10621 ctcaacacgt tttaccgcaa attatcatca ctactgaaat cgattacacc aaccacacca
    10681 gccaaatatt tgtaatattt tcatattatt attcagcttt cacagttgtt acatttcttt
    10741 tcagtaaagt cttaattgca gataacaacc tttaatctat gatgatataa ctcaattatt
    10801 ttcatgcact taaatcataa ctaagataaa tgttagtgta agcgattaca ctgatgtgat
    10861 ttgcttcaca tctttttacg tcgtactcac ctatcttaat tcacaataaa aaataaccat
    10921 attggagggc atcatgcctg acgctaaaaa acaggggcgg tcaaacaagg caatgacgtt
    10981 tttcgtctgc ttccttgccg ctctggcggg attactcttt ggcctggata tcggtgtaat
    11041 tgctggcgca ctgccgttta ttgcagatga attccagatt acttcgcaca cgcaagaatg
    11101 ggtcgtaagc tccatgatgt tcggtgcggc agtcggtgcg gtgggcagcg gctggctctc
    11161 ctttaaactc gggcgcaaaa agagcctgat gatcggcgca atcctgtttg ttgccggttc
    11221 actgttctct gcggctgcgc caaacgttga agtactgatt ctttcccgcg ttctgctggg
    11281 gctggcggtg ggtgtggcct cttataccgc accactgtac ctgtcagaaa ttgcgccgga
    11341 aaaaattcgc ggcagtatga tctcgatgta tcagttgatg atcactatcg ggatcctcgg
    11401 cgcttatctt tctgataccg ccttcagcta caccggtgca tggcgctgga tgctgggtgt
    11461 gattatcatc ccggcaattt tgctgctgat tggtgtcttc ttcctgccag acagcccacg
    11521 ttggtttgcc gccaaacgcc gttttgttga tgccgaacgc gtgctgctac gcctgcgtga
    11581 caccagcgcg gaagcgaaac gcgaactgga tgaaatccgt gaaagtttgc aggttaaaca
    11641 gagtggctgg gcgctgttta aagagaatag caacttccgc cgcgcggtgt tccttggcgt
    11701 actattgcag gtaatgcagc aattcaccgg gatgaacgtc atcatgtatt acgcgccgaa
    11761 aatcttcgaa ctggcgggtt ataccaacac caccgagcaa atgtggggga cagtgattgt
    11821 cggcctgacc aacgtacttg ccacctttat cgcaatcggc cttgttgacc gctggggacg
    11881 taaaccaacg ctaacgctgg gcttcctggt gatggctgct ggtatgggcg tactcggtac
    11941 aatgatgcat atcggtatcc actctccgtc ggcgcagtat ttcgccatcg ccatgctgct
    12001 gatgtttatt gtcggttttg ccatgagtgc cggtccgctg atttgggtac tgtgctccga
    12061 aattcagccg ctgaaaggcc gcgattttgg catcacctgc tccactgcca ccaactggat
    12121 tgccaacatg atcgttggcg caacgttcct gaccatgctc aacacgctgg gtaacgccaa
    12181 caccttctgg gtgtatgctg ctctgaacgt actgtttatc ctgctgacat tgtggctggt
    12241 accggaaacc aaacacgttt cgctggaaca tattgaacgt aatctgatga aaggtcgtaa
    12301 actgcgcgaa atcggcgctc acgattaatc tcctcaggct tcctcccatc atggaggaag
    12361 ccacctcttg cagtcatctt ttcttcgctc tatcctctgc cgctatgaaa acatcccgtc
    12421 tccctatcgc catccaacag gccgttatgc gtcgcctgcg ggaaaaactc gcccaggcca
    12481 acctgaagct agggcgtaac tacccggagc caaaactctc ttacacccag cgcggaacct
    12541 ctgccggaac agcctggctg gaaagctatg aaattcgtct caatcccgtt ttgctgttgg
    12601 aaaacagtga agcctttatt gaagaagtgg tgccgcacga actggcacat ttgctggtat
    12661 ggaaacattt cggccgcgta gcgccacatg gcaaagagtg gaagtggatg atggaaagcg
    12721 tgctgggcgt tcccgcccgt cgtacgcatc agttcgaact gcaatccgtg cgccgcaaca
    12781 ccttccccta ccgctgcaag tgccaggagc atcagcttac cgtacgccgt cataatcgcg
    12841 tagttcgtgg cgaagccgtc tatcgctgtg ttcactgcgg cgaacagctg gttgcgaaat
    12901 aaccacctga actatcagga actttcctga tctggctgat tgcataccaa aacaactttc
    12961 gctacgttgc tggctcgttt taacacggag taagtgatgt accgttattt gtctattgct
    13021 gcggtggtac tgagcacagc attttccggc ccggcattgg ccgaaggtat caatagtttt
    13081 tctcaagcga aagccgcggc ggtaaaagtc cacgctgacg cgcccggtac gttttattgc
    13141 ggatgtaaaa ttaactggca gggcaaaaaa ggcgttgttg atctgcaatc gtgcggctat
    13201 caggtgcgaa aaaatgaaaa ccgtgccagc cgcgtagagt gggaacacgt cgttcctgcc
    13261 tggcaattcg gtcaccagcg ccagtgctgg caggacggtg gacgtaaaaa ttgcgccaaa
    13321 gatccggtct atcgcaagat ggaaagcgat atgcataacc tgcagccgtc agtcggtgag
    13381 gtgaatggcg atcgcggcaa ctttatgtac agccagtgga atggcggtga aggccagtac
    13441 ggtcaatgcg ccatgaaggt cgatttcaaa gaaaaagttg ccgaaccacc agcgcgtgca
    13501 cgcggtgcca ttgcgcgcac ctacttctat atgcgtgacc aatacaacct gacactctct
    13561 cgtcagcaaa cgcagctgtt caacgcatgg gacaagatgt atccagttac cgactgggag
    13621 tgcgagcgtg atgaacgcat cgcgaaggtg cagggcaatc ataacccgta tgtgcaacgc
    13681 gcttgccagg cgcgaaagag ctaacctaca ctagcgggat tctttttgtt aacccctacc
    13741 ccacgcgtac aaccgcgtgg ggagacgacg cggattttta actatgcgta tcccccgcat
    13801 ttatcatcct gaaccactga ccagccattc tcacatcgcg ctttgcgaag atgccgccaa
    13861 ccatatcggg cgcgtactgc gtatggggcc gggacaggcg ctgcaattgt ttgacggcag
    13921 caaccaggtc tttgacgccg aaattaccag cgccagcaaa aaaagcgtgg aagtgaaggt
    13981 gctggaaggc cagatcgacg atcgcgaatc tccgctgcat attcacctcg gtcaggtgat
    14041 gtcgcgtggt gaaaaaatgg aatttactat ccagaaatcg atcgaactcg gtgtaagcct
    14101 cattacgcca cttttttctg agcgctgcgg cgttaaactg gatagtgaac gtctgaacaa
    14161 gaagctccag cagtggcaga agattgcaat tgctgcctgt gagcagtgtg gccgtaaccg
    14221 ggtgccggaa atccgtccag cgatggatct ggaagcctgg tgtgcagagc aggatgaagg
    14281 actgaaactg aatcttcacc cgcgcgccag taacagcatc aatacgttgc cgttaccggt
    14341 cgaacgcgtc cgcctgctga ttggcccgga aggcggttta tcggcagatg aaattgccat
    14401 gactgcccgc tatcaattta ctgatatcct gttgggacct cgcgttttgc gtactgagac
    14461 aactgcgctc accgccatta ccgcgctaca agtgcgtttt ggcgatttgg gctaacggag
    14521 aagaataatg atcaagctcg gcatcgtgat ggaccccatc gcaaacatca acatcaagaa
    14581 agattccagt ttcgctatgt tgctggaagc acagcgtcgt ggttacgaac ttcactatat
    14641 ggagatggcc gatctctatt tgatcaatgg tgaggctcgc gctcgtaccc gtactttgag
    14701 cgtcgaacag aactacgata aatggtacga gttcacgggt gagcaggatc tgccgctggc
    14761 cgatctcgat gtgatcctga tgcgtaaaga cccgccgttt gataccgagt ttatctactc
    14821 gacctatatt ctggaacgtg ccgaagataa agggacgctg atcgttaaca agccgcagag
    14881 cctgcgcgat tgtaacgaaa aactgttcac tgcctggttc tctgacttaa caccagaaac
    14941 gctggtcaca cgcaataaag cgcagctaaa agctttctgg gaaaaacaca gcgacatcat
    15001 tcttaagccg ctggacggta tgggcggcgc gtcgattttc cgcgtgaaag aaggtgatcc
    15061 aaacctcggc gtgattgccg aaaccctgac tgagcatggc actcgctact gcatggcgca
    15121 aaattacctg ccagccatta aagatggcga caaacgcgtg ctggtagtgg atggcgagcc
    15181 ggtgccgtat tgcctggcgc gtattccgca ggggggcgaa acccgtggca atctggctgc
    15241 cggtggtcgc ggtgaacctc gtccgctgac ggaaagtgac tggaaaatcg cccgtcagat
    15301 tgggccgacg ctgaaagaaa aagggctgat ttttgttggt ctggatatca tcggcgaccg
    15361 tctgactgaa attaacgtca ccagcccaac ctgtattcgt gagattgaag cagagtttcc
    15421 ggtgtcgatt accggaatgt taatggatgc catcgaagca cgtttacagc agcagtaacc
    15481 caccttagcg agaaggatct cgttgagact ctgagtgaca gcgcccttct ttccacgcat
    15541 actgggcgct gttgcttttt tgaaccagga aacagaacct ctgacaatga atttacagca
    15601 tcactttctt attgccatgc ctgctctcca ggatccgatt ttccgtcgtt ccgtggtcta
    15661 catttgcgaa cataatacca atggtgcaat ggggatcatc gtcaacaagc cgctggaaaa
    15721 tctcaaaatt gaagggattc tggaaaagct gaagatcacg ccggagccgc gtgatgaatc
    15781 aatccgtctg gataaaccgg ttatgctcgg cggtccgctg gctgaagatc gcgggtttat
    15841 tttgcatact ccgccttcca attttgcttc cagcattcgc atttcagaca acacagtgat
    15901 gaccacttcc cgcgatgtgc tggaaacgct cggcaccgat aaacaaccgt ctgacgtatt
    15961 ggtggctctg ggttatgcct cctgggagaa aggtcaactg gaacaagaaa ttctcgataa
    16021 cgcgtggcta acggccccgg cagatctgaa tattctgttc aaaacgccga ttgccgaccg
    16081 ctggcgcgag gcggcaaaac tgattggtgt ggatattctc accatgcctg gtgtggcagg
    16141 acacgcctga tgagtggaac cttactcgcc ttcgacttcg gcaccaaaag cattggcgta
    16201 gcggtcggcc aacgcattac cggcaccgct cgccctttgc ctgcaattaa agcgcaggac
    16261 ggtacgccgg actggaacat tatcgagcgt ttactgaaag agtggcagcc ggacgaaatc
    16321 atcgtcggtt tgccgctgaa tatggacggc accgaacagc cgttaaccgc cagagcgcgt
    16381 aaatttgcca accgtattca tggtcgtttc ggtgttgaag taaagctcca tgacgagcgt
    16441 cttagcaccg tggaggcacg ttccggtctg tttgaacagg gcggctatcg ggcgctcaac
    16501 aaaggcaaag tcgactctgc ctctgcggtt attattctcg aaagctattt cgagcaggga
    16561 tattaaggcg atttactagc gcacagattt ctgacaatgt gctcgttgtt tcatgttgga
    16621 tgcggcgtaa acgccttatc caacctacag tgagtgcgaa ttcaaagtta cgcttccctt
    16681 gtaggcccga taagcttgcg catcgggcat atttacaatt cgtatcagac acagcaacgt
    16741 cacaagcgcc cttctttcac ccgctgctga taactctgct gaaacgttat catccccacc
    16801 tgctgcccgg tttgaataac atgcggtaac tggtgggttt tcccttcacg aatcaaattc
    16861 cccaccgcgg gtgtgttaat cagtaattca aacagcgcca cgcgtccttc ctgtttatcc
    16921 acttccagct tttgtgacaa caccgcccgt aaactacctg ccagttgatt acgcacggga
    16981 tctttttcct gcgccggaaa cgaatccacc agtcgctcaa ctgcctgcgc tgcgccgcgc
    17041 gtgtgtaatg tcgccagcac cagatgcccg gtttctgccg ccgtcagcgc cagacggatt
    17101 gtctcgctat cacgcagctc tccgagcaaa atcacatcag gatcttcccg caatgcagcc
    17161 cgcaatcccg atgcgaaagt catacagtgc aaaccaatct cccgctgttg gatcaaacat
    17221 cgctgactgg tatagagata ttccacagga tcttccagcg tcagaatatg cgcatcggca
    17281 tgttgattga gatagccaac catcgccgcc agcgtggtag atttgccgct ccccgtcgcc
    17341 cccgtcacca gaatcaggcc attctcgctc ttgagtaatt ccggcaatac cggtggcgca
    17401 ccaagctgtt cgagctgtgg acagtgcgaa ggtaacaacc gtaatgccag agaaatacct
    17461 tgccgttgcg cgaacgcact gccacgcaac cgctggtttt ccgccagcga cacagcaaaa
    17521 tccaactgac cattctccag caatattgtc cgctgatcgt catccagcca ctcccgcagt
    17581 agctcttcga cgtccagcgc atcaaacggc gcagcttcca ttcgcccgcg aatgcgccat
    17641 cgtgcgggcc aggcgctgca caggtgtaga tccgagacgt tatgctttac actaagggcc
    17701 acaatttctt ccatattcat actaagatcc tcggaaaatg aacgatattg cgcataacct
    17761 ggcacaggtc cgggacaaaa tctcagcggc tgcaacgcgt tgcggccgtt ctccagaaga
    17821 aattacgctg cttgcagtca gtaaaacaaa acctgcgagc gccatcgcag aagccattga
    17881 tgccgggcag cgtcaatttg gtgaaaacta cgttcaggaa ggggtagata aaattcgcca
    17941 ctttcaggaa ctgggcgtaa caggattaga atggcatttt attggcccgt tgcagtctaa
    18001 taaaagccgc ctggtggcag agcatttcga ctggtgtcat accatcgacc gtttgcgcat
    18061 cgctacccgt ctgaacgacc agcgcccggc agaacttccc cctcttaacg tactgattca
    18121 aattaacatt agtgatgaaa acagtaagtc cgggattcaa ctggctgaac tggacgagct
    18181 ggcagctgcg gtcgctgaac taccgcgttt acgtctgcgc gggctgatgg caatccctgc
    18241 gcctgagtca gaatatgtaa ggcagtttga agttgcacgc caaatggctg tagcatttgc
    18301 cggactgaaa acgcgctacc cgcatatcga cacgctctct ctgggaatgt cggacgatat
    18361 ggaagccgcc attgcggcag gtagcacgat ggttcgtatc ggcactgcaa tttttggtgc
    18421 gcgtgattac tctaaaaaat aaggaattaa aggaacgcca tgaatacgtt gactttcctg
    18481 ctttcaacgg tcattgagct gtataccatg gtgctgttat tacgcatctg gatgcagtgg
    18541 gctcattgtg atttttacaa ccccttctca cagtttgtag tgaaggtaac gcagccgatt
    18601 atcgggccac tgcgccgcgt tattccggca atgggcccca ttgatagcgc ctcgctgctg
    18661 gttgcctata ttctcagttt cattaaagcc atcgtgctgt ttaaagtggt gaccttcctg
    18721 ccaatcattt ggattgccgg tttattgatt ctgctgaaaa ccatcggcct gctgattttc
    18781 tgggtcctgc tggtgatggc gattatgagc tgggtaagcc agggtcgtag cccgattgaa
    18841 tacgtgctga ttcagctggc cgatccgctg ctgcgcccga ttcgccgctt gctaccggca
    18901 atgggtggga ttgatttctc gccgatgatc ctcgttctgc tgctgtatgt catcaatatg
    18961 ggtgtcgcag aagtcttgca ggcgaccgga aatatgctgc tgccggggct gtggatggcg
    19021 ttatgagtgc cgtaacagtt aatgatgacg gtctggtttt acggctctat attcagccga
    19081 aagccagccg tgattctatt gtcggtttac atggcgacga ggtaaaagtc gccattaccg
    19141 cgccgccggt tgacggccag gccaacagcc atctggtgaa gtttctcggt aagcaattcc
    19201 gggttgccaa aagccaggtg gtgattgaaa aaggcgaact tggccgccac aaacaaatta
    19261 aaatcattaa tccgcaacaa atcccgccag aaatcgcggc gttaattaat taggtatcct
    19321 atgcaaaaag ttgtcctcgc aaccggcaat gccggtaaag tgcgtgagct ggcgtcgctg
    19381 cttagcgact tcggtcttga tatcgtggcc caaacagacc tcggcgtaga ttccgctgaa
    19441 gaaaccggcc tgacctttat cgaaaacgcg attctgaaag cgcgccatgc ggcaaaagtg
    19501 accggtttac cggcaattgc cgacgactcc ggtctggcgg tagatgcgct gggtggcgcg
    19561 ccgggtattt actccgcgcg ttattccggt gaagacgcga ccgatcaaaa gaatctgcaa
    19621 aaactgctgg aaacaatgaa agacgtaccg gacgaccaac gtcaggcgcg tttccactgc
    19681 gtgctggtat atctgcgtca cgcggaagat cccactccgc tggtgtgcca cggcagctgg
    19741 ccgggcgtga ttactcgtga accagcgggc actggtggct ttggttatga tccaatcttc
    19801 ttcgtacctt ccgaagggaa aactgctgcc gaactgaccc gcgaagaaaa gagcgccatt
    19861 tcccaccgtg gtcaggcgtt gaaactgctg ctggacgctt tacgtaatgg ttaaattacc
    19921 gccgctgagt ctctacattc acatcccgtg gtgcgtgcag aaatgcccgt actgcgattt
    19981 caactctcac gcgttgaaag gagaagtgcc gcacgacgat tatgttcagc atctgcttaa
    20041 cgatctgaac aacgatgtgg cttacgctca gggccgtgaa gtaaagacaa tctttattgg
    20101 cggtggtacg ccgagcctgc tttccggccc ggcgatgcaa acgctgctgg acggcatacg
    20161 tgcgcgtttg ccgctggcag cggatgcaga aattacgatg gaagcgaatc ctggtacggt
    20221 tgaagccgat cgctttgttg attatcagcg tgctggtgtg aaccgcatct ccattggcgt
    20281 acagagtttt agcgaagaaa agctgaaacg acttgggcgc attcatggcc cgcaagaagc
    20341 gaaacgagcg gcaaatctgg cgagcggttt agggttacgt agctttaacc tcgatttgat
    20401 gcatgggcta ccggatcaat cactggaaga ggcgcttggc gatctacgcc aggctattga
    20461 actgaatccg ccgcatcttt cctggtatca actgaccatc gaacccaata cgctgtttgg
    20521 ctcgcgccct cctgtactgc cggacgatga cgcgctgtgg gacattttcg aacaggggca
    20581 tcagttatta accgcagcgg gttatcagca atatgaaacc tccgcttacg ccaaacccgg
    20641 ttatcagtgc cagcacaatc tcaactactg gcgctttggt gactacatcg gtattggctg
    20701 cggcgcgcat ggcaaagtga ccttcctgga tgggcgcatt ctgcgtacca ccaaaacgcg
    20761 tcatccgcgt ggttttatgc aggggcggta tctggaaagc cagcgtgatg tcgaagccgc
    20821 agataagccg tttgagttct ttatgaatcg cttccgtttg ctggaagccg cgccgcgcgt
    20881 ggagtttagc cagtatactg gcctttcaga agaggttatt cgccctcagt tagacgaggc
    20941 tattgctcag ggttatctca cagaatgtgc ggattactgg cagataacgg aacatgggaa
    21001 gttgttttta aattcgctgc tggagctttt tctggctgag taaatttgta ttgccggatg
    21061 cggcgtgcgt gtacgcagca tccggcaaca actcatgcgt catcgcaaaa attacttaat
    21121 caccccattg cgccgcagtt gttcggtatc ttttttccag cgttcattag cctggttgat
    21181 atcgtcaatt ttcatcaaaa tcgcgacttt tttactgttt atttctgaaa ctttcatcgt
    21241 taacggatat tgcccttttt cgagcgttat ccagtcatcc tgcaatttac ggctaagttt
    21301 ttgtgattgc agaaaagtct gtcgccgttg ttcgttgata tcaaaatctc gtttctgctg
    21361 aattggcact tcataacact cttcactctg tttatgacat gccgcaatcg ccggttgata
    21421 aacctctttg tcatatttaa ccgcgaacgc ctcactatcg ttctgtttat taaaatcatc
    21481 acgctgttgg tgaatttttt taaaggcgtc ttcgcgggtc atttgcttac cgtttgcatc
    21541 ttttccccaa tatgcatccg ctgctttctg cgccgccacc atttgcttat caagcgcttt
    21601 tacatccttt ttcagtgcag gaatcgagtt attctggtta ttcaacgcag actcaagctg
    21661 actaaagcga taattgaaat cttcgctatt cacgatcaga tatttattat tcgttttgat
    21721 atcgtcaacc acccgcccac gatcgctggc tgccgcctga aaagagtaaa agttcaccga
    21781 ccagccagac gcgggcgttc ctttactggt taacatcgcc gagaatttca ccggtttatc
    21841 tttcgtccag gtctgttcga gcagctcgta atctgccaac tgaccgaccc aggtatagag
    21901 atcgtcactg gaagagacat cgccttccgc tgaccaggtg gcctgattac ccttagcatc
    21961 aagatttttt aaggtgatga catcaagctt gagaatgccg tgatactgct ttttgaattg
    22021 atcttttaag atattttcag ttggcggttc accatctgcc cagacattac cagtcatcaa
    22081 cataaacagc gccgtaccaa caatccattg ctttttcacc cgaaaaccct cgcgcggaat
    22141 aatttattcc ggtgattatc attagggtaa taaaaattgg caatggacgt gagtctgaag
    22201 tgaataagcc ccggcgcgat accggggcga agtgattagt actgattgaa gatctgctgg
    22261 atctgctgcg gatctttagt ttgcgtcaga gccagttgca gcagaacgcg cgctttttgc
    22321 gggttcaaca tgccggaggc gacgaagccg tatttcgcat catccacttc ggcatcctga
    22381 gtggtagcgc ccgtcggtac gcgggaagaa cgcactactg cagtgccgtt tttcgcagcg
    22441 gttgcaaggg tgtcaaatac ggttttatac aggttgccgt tacccacgcc agcgctaacg
    22501 atgccatcat agcccgcatc taccagtgct ttagccggaa gatcggatgc gttagcgtag
    22561 ttataaacaa tgccgacttt cggcagttca ttcagcttag agacatcgaa cggcgtgtcg
    22621 ctggtgtgct tacgtgccgg ggtacgttgg tagtcaatct taccgttgtg aatgtaaccc
    22681 agaggaccgt agttaacaga cttgaaggtc gctacatcgg tggtgttggt tttggtgaca
    22741 tcacggccat caagcacggt gtcgttcatc actaccagta cgccacgatt agcggaggct
    22801 ttatcagctg cggtcactac cgcgttatac aggttgaatg gaccgtctgc gctcatagac
    22861 gtggacgggc gcattgcacc gaccatcacc accggtttgt cgcatttcac cgtcaggtcg
    22921 aggaagtaag cggtttcttc catcgtgtcg gtaccgtggg taatgacgaa gccgtcagtt
    22981 ttatcgcagt cggtgttaat ttttttcgcc agtgtcagcc agacatcatc gttcatgtcc
    23041 tgggagccaa tattcactac ctgctcgcct ttaacgttcg caatgtcctt cagttgcggc
    23101 accgcattaa ccagattttc tacgccaact ttacccgctg tgtagttaga tttggttgcg
    23161 gagtcaccac caccggcaat ggtcccgccg gttgctaaaa tggtgatatt gggtaatgcc
    23221 aatgctgcac cactaaaacc cataaccagt gcggcaagtg ccgtcttttt gaaaaactcc
    23281 atttcattcc tccagttacg tgaacgctac gcattatccc ttagctttgc atgggaaatt
    23341 tgacgttaaa caatttacaa cgtgaatata ttttggagat ctacaaagtt agaggcaggt
    23401 aacaaaacga agaattaaac ggcataaaaa agtattatgc cgtcttaaaa tagaggatta
    23461 ttttaaattc ccgaccaggg ctttgcggct atcttccaga gtcacaacgc ggctacaaac
    23521 atctttgcca aactgctgga aatctttttc ctgctttttc cactcggttt ggattgagga
    23581 ttgcaggccg cccaggcttc ccagcacgtt ctgtaatggg ttaccgccgc ttttcagcac
    23641 cgctttcgcg cccatttcat taatgctgtc ctgtaaaatt ccgcccattg cctgattcac
    23701 taattgctgg ccttcggcac gaacctgatc aatggcttta tagtgaaacg tcaggccatc
    23761 gctgcgcgtt tcgataatgc ggttcatctg ctctttcagc tgcgcatcaa gtttggtcag
    23821 acggctgcgc attttgctgc tttcgcccat ctcctgaacg ataattttat ccagcgcaat
    23881 acgagctttc tcgacgcggc ttttcgcgcc ttcatcaatc cacggcaggg tgctacgtag
    23941 ttcagcctga taatccttcg cctgctcgcg ctgggcggca ttcagggaat attgcttacc
    24001 gttatacatc acgttgccgt ctggcgtgat caccagattg ccgttttcgc ccttcacctg
    24061 cacggtttgc gggctgacaa tcacatcgtc acgcggcgtg acgctgcact ggtagtcggc
    24121 gtgagcggtc attgccgtca ctgaaagtgc tgccgccagc agcattttgc gcatcatagt
    24181 cttccctcaa gaacaaatca ggccagcatt tgctggcccc agattgataa caaagtgcgc
    24241 gttttccatg ccggatgcgg cgtaaacgcc ttatccggcc tactcgatcg tgcatctttg
    24301 taggcctgat aagcgtagca catcaggcag ttttgcattt gtcatcgccc gtatgctttc
    24361 ttagtcccac caaacgtcga aaagttcgct ggtgcgtacc tcttccagtt tgcgttcttc
    24421 cagccactta cgcacaatcg cctgatgttc ttcggtgcat ttgccgattt cctgcatgca
    24481 gatcagacct tcccaggcca gataaccgct gccgtcaaag gccagtttgt tcggttcgat
    24541 aacctcgtta ataaagtcat caacggtttt atcaatctgt tcttccgatg taccttccgg
    24601 gaatcgccat gccaccgaaa atcctaattc ctggaattcg tcgatgtgca tttttttacg
    24661 cagacgacgg ctacggttct ttgccattat ttcaccctct cgaacattaa gtcccatact
    24721 ccgtgaccaa gacgatgacc acgttgttca aatttcgtca ccggacgtga tgccggacgc
    24781 ggtacgtaat cattgctctc tgacaggttt ttataaccgt caatagaaga catcacttca
    24841 agcatatgtt ccgcataagg ttcccagtcg gtcgccatat ggaatatgcc ccccagctgc
    24901 agtttgcttt ttaccagctc ggcaaacggc acctgaacga tacggcgttt attatggcgc
    24961 gctttgtgcc acgggtcagg gaaaaagagc tgcaccatgc gcaatgaatt gtcaggaatc
    25021 attttatgca gcacttcaac cgcatcgtga cacatcacgc gcaggttgct taagccctct
    25081 tcatgcgcag aagacaggca cgcaccaacg cccggtgaat gcacttcaat gccgaggaag
    25141 tcctgctcgg ggcgatcttt agccattgcc accaacgacg cgcccatgcc aaaaccaatc
    25201 tcaagcgtca ccggcgcttc acggccaaaa agcgcaggga aatccagcat atcttcgctg
    25261 aactcaacgc ccatcaccgg ccagtagttt tccagcgcat gttcctggcc tttggtcagt
    25321 cgcccctggc ggcgcacaaa actacggata cggcgcagcg ggcggccgtt ttcatcaaat
    25381 tccggtgaga tgacgtcgtt tttcataaag atttagtcgc ttgtgaaagt gttctgaaaa
    25441 cgggcattat ccaaagttag ttgccggatg caagcatgat aaggccgtgg ctgcggaaag
    25501 ttccggttta caccctgccg tcgctgtgct gcaatcttgc ccccaacaac agtgaattcg
    25561 gtgaccatgc aagcgtcgca attttcagcc caggttctgg actggtacga taaatacggg
    25621 cggaaaacgc tgccctggca aattgacaag acgccctaca aagtatggct ctcagaagtg
    25681 atgttgcaac aaactcaggt tgcgaccgtt atcccctatt ttgaacgctt tatggtgcgc
    25741 ttcccaacgg tgaccgatct cgccaatgcg ccgctcgacg aagttctcca cttgtggacc
    25801 gggcttggct attacgcccg agcgcgcaat ctgcataaag cggcacaaca agtggcggcc
    25861 ttacacggcg gtaaattccc ggaaaccttt gaggaagttg cagcactgcc gggcgtcggg
    25921 cgttccaccg caggcgcgat tctctcgctt tctctgggta agcactttcc gattctcgac
    25981 ggtaacgtca aacgcgtgct ggcgcgctgc tatgctgtaa gcggctggcc cgggaaaaaa
    26041 gaggtcgaga ataaactatg gagtttgagc gagcaggtga cgcccgcggt tggcgtggaa
    26101 cggtttaacc aggcgatgat ggatttgggc gcgatgattt gtacgcgctc taagccgaaa
    26161 tgctcgctct gtccgctaca aaacggatgt attgccgccg ccaacaatag ctggtcgctt
    26221 tatccgggca aaaaaccgaa acagacgctg ccagagcgca ccggctactt tttgctgtta
    26281 cagcacgaag atgaagtatt gctggcgcag cgtccgccga gcggattgtg gggcggttta
    26341 tactgtttcc cgcagtttgc cgatgaagaa agtttgcggc agtggctggc gcaacgacag
    26401 attgctgccg ataacctgac gcagctgacc gcgtttcggc ataccttcag ccatttccac
    26461 ttagatattg tgcctatgtg gcttcccgtg tcgtcattca ccggctgcat ggatgaagac
    26521 aatgcgctct ggtataactt agcgcaaccg ccgtcagttg gcctggcggc tcccgtggag
    26581 cgtttgttac agcagttacg cactggcgcg ccggtttagc gcgtgagtcg ataaagagga
    26641 tgatttatga gcagaacgat tttttgtact ttcctgcaac gtgaagcaga aggtcaggat
    26701 tttcagctgt accccggcga actgggaaaa cgcatctata acgagatctc caaagaagcc
    26761 tgggcgcagt ggcagcacaa acaaaccatg ctgattaatg aaaagaaact caacatgatg
    26821 aatgccgagc accgcaagct gctggagcag gagatggtca acttcctgtt cgagggtaaa
    26881 gaggtgcata tcgagggctt tacgccggaa gataaaaaat aaaaacagtg ccggagcacg
    26941 cctccggcaa cttgcataaa aacaaacaca acacgcaccc ggaatgatga aaaaatatct
    27001 cgcgctggct ttgattgcgc cgttgctcat ctcctgttcg acgaccaaaa aaggcgatac
    27061 ctataacgaa gcctgggtca aagataccaa cggttttgat attctgatgg ggcaatttgc
    27121 ccacaatatt gagaacatct ggggcttcaa agaggtggtg atcgccggtc ctaaggacta
    27181 cgtgaaatac accgatcaat atcagacccg cagccacatc aacttcgatg acggtacgat
    27241 tactatcgaa accatcgccg ggacagaacc tgccgcgcat ttgcgccggg caataatcaa
    27301 aacgttgctg atgggggacg atccgagttc ggtcgatctc tattccgacg ttgatgatat
    27361 tacgatttcg aaagaacctt tcctttacgg tcaggtggtg gacaacaccg ggcagccgat
    27421 tcgctgggaa ggtcgcgcga gcaacttcgc ggattatctg ctgaaaaacc gtctgaagag
    27481 ccgcagcaac gggctgcgta tcatctacag cgtcaccatt aacatggtgc cgaaccacct
    27541 tgataaacgt gcgcacaaat atctcggcat ggtccgccag gcatcacgga aatatggcgt
    27601 tgatgagtcg ctgattctgg caattatgca gactgaatct tcctttaacc cgtatgcggt
    27661 cagccgttcc gatgcgctgg gattaatgca ggtggtacaa cataccgccg ggaaagatgt
    27721 gttccgctcg caggggaaat ccggcacgcc gagccgcagt ttcttgtttg atcctgccag
    27781 caatattgat accggcaccg cgtatctggc gatgctgaac aacgtttatc tcggcggaat
    27841 tgataaccca acatcgcggc gttatgccgt catcaccgcc tataacggcg gcgcaggcag
    27901 cgtgctacga gtcttttcga atgataagat tcaggctgcc aatattatta acaccatgac
    27961 gccgggcgat gtttatcaga cgctgacgac ccgccatccc tctgcggaat ctcgccgtta
    28021 tctttataaa gtgaataccg cgcaaaaatc ttaccgccgc cgataattcc actaaccgcc
    28081 cctgacgatg ctcaggggta aaaatgttat ctacatcaca atttcgtttt gcaaattggg
    28141 aatgtttgca attatttgcc acaggtaaca aaaaaccagt ccgcgaagtt gatagaatcg
    28201 catcatctcg cacggtcaaa tgtgcttttt caaacactca tccgcatcac gatgtgagga
    28261 aattaacatg aatcttaagc tgcagctgaa aatcctctct tttctgcagt tctgtctgtg
    28321 gggaagttgg ctgacgaccc tcggctccta tatgtttgtt accctgaagt ttgacggtgc
    28381 ttctatcggc gcagtttata gctcactggg tatcgccgcg gtctttatgc ctgcgctgct
    28441 ggggattgtg gccgacaaat ggttaagtgc gaaatgggtc tatgccattt gccacaccat
    28501 tggcgctatc acgctgttca tggcggcaga ggtcactacg ccggaggcga tgttccttgt
    28561 gatattgatt aactcgtttg cttatatgcc aacgcttggg ttaatcaaca ccatctctta
    28621 ctatcgcctg caaaatgccg ggatggatat cgttactgac ttcccgccaa tccgtatctg
    28681 gggcaccatc ggctttatca tggcaatgtg ggtggtgagc ctgtccggct tcgaattaag
    28741 ccacatgcag ctgtatattg gcgcagcgct ttccgccatt ctggttctgt ttaccctgac
    28801 tctgccgcat attccggttg ctaaacagca agcgaatcag agctggacaa ccctgctggg
    28861 cctcgatgca ttcgcgctgt ttaaaaacaa gcgtatggca atcttcttca tcttctcaat
    28921 gctgctgggc gcggaactgc agattaccaa catgttcggt aataccttcc tgcacagctt
    28981 tgacaaagat ccgatgtttg ccagcagctt catcgtgcag catgcgtcaa tcatcatgtc
    29041 gatttcgcag atctctgaaa ccctgttcat tctgaccatc ccgttcttct taagccgcta
    29101 cggtattaag aacgtaatga tgatcagtat tgtggcgtgg atcctgcgtt ttgctctgtt
    29161 tgcttacggc gacccgactc cgttcggtac tgtactgctg gtactgtcga tgatcgttta
    29221 cggttgcgca ttcgacttct tcaacatctc tggttcggtg tttgtcgaaa aagaagttag
    29281 cccggcaatt cgcgccagcg cgcaggggat gttcctgatg atgaccaacg gcttcggctg
    29341 tatcctcggc ggcatcgtga gcggtaaagt ggttgagatg tacacccaaa acggcactac
    29401 cgactggcag accgtatggc tgattttcgc aggttactcc gtggtgctgg ccttcgcgtt
    29461 catggcgatg ttcaaatata aacacgttcg tgtcccgaca ggtacacaga cggttagcca
    29521 ctaattacgc aaagaaaaac gggtcgccag aaggtgaccc gtttttttat tcttacttca
    29581 acacataacc gtacaaccgt ttcatgccat ccgcatcggt ttcgctatag acaccttgca
    29641 actccggcga aaatcccggc aacaaattca cgccttcttc cagcgcaagg aaataacgtt
    29701 gaaccgcccc accccagact tccccgggta ccacgcaaag cacgccaggt ggataaggca
    29761 acgccccttc tgccgcaatt cgcccttcgg catcacgaat ccgcaccaac tccacttcac
    29821 cgcgaatata agcgctatgc gcatcctggg gattcatcac cactgacggg aaactctgct
    29881 ggcggaacat cgctttttgt aggtctttga cgtcgaaact gacatacaaa tcgtgcatct
    29941 cctgacacaa ctggcgcagg gtgtagtcgc gatagcgcac cggatatttg ttataaacgc
    30001 tcggcaacac ctcagccagc ggcgaatcat cctcaatatg ctgttcaaac tgcgccagca
    30061 tcgccaccag ttgtgccagc ttctcgtggc tttccgccgg agttaataag aacagaatgg
    30121 agttgagatc gcacttctcc ggcacaatgc cgttctcacg caggtagtgc gccagaatcg
    30181 tcgccggaac gccaaagtcg ctatattcgc cggtttcggc atcgataccc ggcgtggtga
    30241 gtaacagctt gcacggatca acaaaatact gatccgcggc atatccttca aagccgtgcc
    30301 aattcgcccc cggctcaaaa ctgaaaaaac ggcggtcgct ggctaacact gacgtcggat
    30361 aatcctgcca caatttgcca tcaacaacgg gcgggataaa cgggcggaac agcttacagc
    30421 gcgcaagaat agccttgcgc gactcaatac ccaactcaac gcactcagcc cacagccgac
    30481 gcccactctc cccttcatga attttggcgt taacgtccag ggcggcgaac agcggataga
    30541 acgggctggt agaagcatgg agcataaagg cattattcaa ccgcttatgc gggcaaaaac
    30601 gcgcctgtcc acggatatgg ttatcttttt tatggatctg cgacgtctgt gagaatcccg
    30661 cctgctgttt gtgcaccgac tgagtcacaa agatccccgg atcgttttcg ttaagttcta
    30721 acagcagcgg cgagctatcc gccatcatcg ggataaactg ttcgtaaccg acccacgcgg
    30781 aatcaaacag aatgtaatca cacagatgcc caacggtatc gatcacctga cgggcgttat
    30841 agacagtgcc gtcataggtt cccagctgaa taatcgccag gcgaaacggg cgcggcaggt
    30901 cggctttttc tggcgcaacg tcgcgaattt gctggcgcag atactcttca ttaaaacagt
    30961 gcgcatcaat accgccaatg aaaccaaacg ggttacgtga agcttccaga tagaccggtg
    31021 tcgcccccgc ctgaatcaac gcgccatgat gattcgactt atggttgtta cggtcgaaga
    31081 gcaccagatc gccacgcgtt aacagcgcat tcgtcaccac tttattcgct gccgatgtgc
    31141 cgttcagcac aaaataggtt ttatcggcat gaaagacttt ggctgcaaat ttctgcgcat
    31201 ctttcgccga tccttcatga ataagcagat cgcccaattt tacgtcagcg ttacacatat
    31261 cggcgcgaaa gatgttctcg ccaaagaaat cgtaaaaatg gcgtccggca ggatgctttt
    31321 taaagaacgc accatgttga tgtccagggc aagcaaaggt gctattaccc atctcaacgt
    31381 actgcgtcag cgtgtcataa aacggtggca gcaaattctc ttcatactga caggctgcgg
    31441 attccagctc cagccactgc tgctcgttgc cgttgattac cgccgtaacg cccgcaggta
    31501 attcaacagc atgttcggaa tacaaaaaca ccggtagatg aaaaccggtg cgcttaagca
    31561 atgcaagaat gccactgcga ctatccgcag cggtaatgac gactgccgcg acgtccgtaa
    31621 aatcagtatc tcccaacgcc accacgcggc gatgagtaga aagtcgggat accagttcac
    31681 tactggcggc aatattcatt gatttcataa gcgcaaaacc cgtttagggg aagtaagaat
    31741 accggacaag gaggaaaacc ctgccccatg agatatgggt caaactggtc accagctccg
    31801 accgccagac atcagtaaaa gcagaaacgc tctgatttta ctgttgtcct gcagtgagcg
    31861 tgcgttaact tcaccgcatg agcagtagca taaaaagaga agagtttcgc gcgaaacggc
    31921 gataagcgag agaatgtaag gaggtggcgt gcatcgggca aactccgtac agagaggaga
    31981 aaattcgcgc aatcatggca cctttcgcta aagcgtgcaa gccaggactt tgcgaacaaa
    32041 caagccatcg acggcgccaa aagttcataa taagaaaatc aaacaataca gctaacagga
    32101 actcttgtgg tcatcggccc ttttatcaac gcaagtgcag tcttactggg tggcgttttc
    32161 ggcgcacttc ttagccaacg cttaccggaa cgtatccgcg tctccatgac atcaattttt
    32221 ggtctggcat cgctggggat tggtatttta ctggtggtga aatgcgccaa ccttccggcg
    32281 atggttttag caaccttact cggagcatta atcggcgaaa tttgtctgct ggaaaaaggc
    32341 gtcaatacag tggtcgccaa agcgcataat ctgtttcacc actcgcgtaa gaagccagcg
    32401 catgaatctt ttattcagaa ttttgtcgcg attattgtcc tgttttgcgc cagcggcacc
    32461 ggaatcttcg gggcgatgaa cgaagggatg accggcgatc cgagtatttt aatcgccaag
    32521 tcatttcttg atttctttac ggcgatgatc ttcgcctgct cgctgggtat tgcggtgtcg
    32581 gtgattagca ttccattact gatcatccag ttaacactgg cgtgggctgc cgcgctgata
    32641 ttaccgctga ccacaccgtc gatgatggca gacttcagcg ccgtaggcgg tttattgctg
    32701 ctggcaaccg gattacgcat ctgtggcatt aaaatgttcc cggtggtcaa catgcttcca
    32761 gcactccttc tggcaatgcc gctttccgcc gcctggaccg cctggtttgc ctgacaatgc
    32821 gtgcaatagc ggcaaagtga tgatagattg tgcagtctgc actaaattga agaaatttga
    32881 ttgacgagac gaggcgaatc aggtttaatg cgccccgttg cccggatagc tcagtcggta
    32941 gagcagggga ttgaaaatcc ccgtgtcctt ggttcgattc cgagtccggg caccaaattc
    33001 atataaacgg acctccacgg aggtccgttt ttcgtttcag aacgccacaa tttaagcgtt
    33061 ctgcctccaa atcaattcta ccgaactcaa ccagattccc cccacatcaa ccccattgtg
    33121 tgggtataat tgcgggtata ccccagttcg acagaatttg taccctcttt aacgcattca
    33181 gaaggctgaa ctatggcact gactgacgca aaaatccggg ctgcaaagcc cactgacaag
    33241 gcttataaac tcactgacgg ggctggcatg ttcctgctgg tacatcctaa tggttcccgt
    33301 tactggcgtc tccgttatcg tattctgggt aaggagaaaa ccctggcact tggtgtgtat
    33361 ccggaagttt ctctctccga agctcgtaca aaacgggatg aggcccgaaa actgatttcg
    33421 gagggggttg acccttgcga acagaaaaga gctaaaaaag tagtccctga tttacagctc
    33481 tcttttgaac atattgcacg acgctggcat gccagtaata aacaatgggc acaatcacac
    33541 agcgataaag tactcaaaag cctcgagact cacgttttcc cctttatcgg caaccgggat
    33601 atcacaacac tcagtacccc ggatctgctt atccctgttc gtgctgcaga agttaaacaa
    33661 atttatgaaa tcgccagtcg tctgcagcaa agaatatctg ctgtaatgcg ttatgccgta
    33721 cagtctggca tcatcagata taacccggct ctggatatgg ctggtgcatt gaccacggta
    33781 aaacgccagc atcgccctgc tctggatctt tcacgcctgc ctgaacttct gtcgcgtatt
    33841 gacggttata aaggccagcc tgtcacccga ctggcagtta tgctgaattt actggttttt
    33901 attcgttcca gtgaactcag atatgcccgc tggtctgaaa ttgatattga caatgccatg
    33961 tggactattc cagccgaacg cgaacctctg ccaggcgtaa aattttcata ccggggctcc
    34021 aagatgcgaa caccacatct tgtgccactc agccaacagg ctgtagccat actggcagaa
    34081 cttcagacat gggcaggtga aaatggtctg atctttacgg gagcacacga cccacgtaaa
    34141 ccaatcagtg aaaataccgt aaataaggcc ctcagagtga tggggtatga cacaaccaag
    34201 gaagtctgtg gccatggatt ccgggcgatg gcgtgcagtg cattgattga atccggctta
    34261 tggtcaagag atgcggttga acgtcagatg agtcatcagg agcgcaacgg agtacgtgcc
    34321 gcgtatattc ataaagcaga acatctggaa gaacgtcggc ttatgctgca atggtgggca
    34381 gattttctgg atgcaaacag ggaggagtgt atcagtccgt ttgaatatgc aaaagttaac
    34441 aatccactga aaaggtgact gaacgccatt tacacacatg ctcttcctct taaggggaag
    34501 agcacccgcc tcaatcaatt tcttttttat gccggcggaa ccatcagcca ggctgaggtt
    34561 ctcattcaat aactcaacgt cttaccacag aacagaattc actgtattat catgggcaac
    34621 gttaatcccg gacaataaaa ggacaccgat gccaggcatc acaattttta tagcctgcag
    34681 gttatggtcc atcctttttt acaggttcag aatatgactg gcaaattacg ctttgaagtg
    34741 aacgataacc agggctgttt catatttccg gaaacctggt ttggctcgtt gctggatgag
    34801 tttgaagaac tgattgatgc atacgatgcg gatgaaatca gcgaaacaag ttacatcaac
    34861 aaactcaggc gccttgcccg acaggagaat gactttattg atgtacacgc tcacttggca
    34921 tacgtatttc tggagcagaa tgccccgcgt aaggcgctga atgctgccct taaagggctg
    34981 gcaattggca atcgtcttat ccctgaaggt ttcagtggca gaatcatctg gatacatcct
    35041 gacaaccgac cttttcttcg tgccctctat gcggcaatcc tggcaaatgc acatttacag
    35101 cgtcatcagg atgccatcat gctcattgaa aaaatactgg attacaatcc cgaagataat
    35161 catggtgcac gctggctact gggaccggaa ctgttacgca ctggcgctca tgaacaggca
    35221 cgccatatac tgcaggaaca tgcagatgaa ttttcacctt actggtatga actcggcctt
    35281 ctgcattttc ttaatgggga actggtaaaa gctgcaactg catttcgtcg cggctttgcg
    35341 gcaaatactt acatcgcaga aatactgtgc ggaaatctgc atccatttcc acttgctgta
    35401 tggcataact tttcaggcgg tccggatact gccgaagatt attatgccac ataccacccg
    35461 ttatgggggc aatatccgga agcattgctg tttgtaaact ggctctataa tcattcctct
    35521 gtgctgcatg aacgggcaga aatcattaaa tgcgccgaaa tgctgatgca ggaagatgat
    35581 ttcgaaatat gcgaaagtat tttaagacag caggagaagt tgcgtgaaag aattgatgag
    35641 acgctttctg agaaaattgt acagaaatgc agaaatatga atggtgaata tatctggccc
    35701 tggatattgc cgttttcagc ggcaggcatg aaacatactg gcatacagta tcagtagata
    35761 ttgcattagt gtatcctgca cacaagtaat aatttattca ccaataataa cactgttaat
    35821 gcccccttcc cctggttgtc agccaggggt tatcttctga atatttcttt tgaaaaggat
    35881 aacacagtaa attattttta tgaattatcc catggactca ttaacaccct ttcatgatgc
    35941 tttattgtca aacacgttat ggctgacatc aaaaaaaacc ggatttcctc tgccagcggg
    36001 taatcacctt cccggtgttt tcggttggtc tggttactcc tgtctggtta ttagcaagat
    36061 aattgctata aacagtggaa aactcatcgt acataatctg gtgatgaaca ttacgcttat
    36121 tttcccttga ccggaagaat cagaggctgt ggtttcagac tgtctgccag tacattcctc
    36181 tctccgttaa aaaccataac gggttcatta tcttcgtctg tcagca
//
LOCUS       DADXDL010000048        36100 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.048, whole genome shotgun sequence.
ACCESSION   DADXDL010000048 DADXDL010000000
VERSION     DADXDL010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36100)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36100)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36100
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.048"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(1748..2062)
                     /locus_tag="IRB70_002648"
     CDS             complement(1748..2062)
                     /locus_tag="IRB70_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632546.1"
                     /translation="MTRDKIEYIASLKYEAEKWRRIGGWGTLISLSALLIDSWFRHID
                     AASLLFESAVLGGFICCWGGNYDRASKHKRELDAICFALFGKDYESSDLDIIEFNKTE
                     LS"
     gene            complement(2062..4818)
                     /locus_tag="IRB70_002649"
     CDS             complement(2062..4818)
                     /locus_tag="IRB70_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632547.1"
                     /translation="MKQACVEAIAQTLGRQPKADELKNIEDRIKEAVQHVHRKNAKEG
                     KSGIPDAQTYMDAAELVRQRVVHDVYKKRQRVAQNAIAISKITDTLDANIPPDQQTPV
                     NLQQFIFAGRRSRDKADISVASAEELAIGAYQDWSRQLSAELLKAGDDVRKFFEQSRA
                     LGEQRFRSVFDRQAAKSAQLQILKEIYGEDTGNPLAKKIAQIWKDVTGRVRHEMNDNG
                     FDIGLREDWHTPYVDDADLIRNAGREEWLASLPVAEQATARLSGRQPPIEFARQKWVD
                     DAYNTQDRSNYVNPDGSIMNDVEYRQALEAIFETKATDGANKIEPGTFMGAGGIKSRG
                     SQHRVMAFKDAQSHFAYMERYTQQPLVGVMMSHLQSSSRDLGVVKAFGPDAERNFSLV
                     LDRIYKRAVTGGKRKKEMEDEAKLVARMFNSMAGLNGVASSSVFSSAVGGLRNLMTSA
                     MLGTSVLTATSDQAIMRANAQALGFTRGGMRLSVNTIKNLFSGDAKKANAELGLLVDS
                     HAAVVSKMGGFDLSRGITGWFAEKTLKWSGLIAMDRANKASFGLLMYKNIGELTRKFK
                     TLDDMKGTDKTILANKGWSNEDWAIMAAAELRPMTTAGHMGMTPDAIYAVPDNVIADI
                     MADRITRIRAGSEKALAALGDLPPERLKRMKEAFDAEAEQTITRMIRNARAEAAHKLL
                     GITHGEMTNAVTTATGIDTYARDDAGELMKSFMLFKTTPFAGFRQLVNRTRDLDTVPA
                     IKFLASYIGGTTLAGMFAIQMNSLLNGNDPLDMTKPTTWVQALLKGGSFGIYGDFIFQ
                     DHTQYGSSIGATMGGPVLSFAEQLTKLLITNPQKALQGEETSFGADALKTARMITPFA
                     NLWYAKAITNHLILQQLQEMANPGYNDRVRDRAQREFDITSWWEPGAIAPRRAPDFGK
                     AVGN"
     gene            complement(4818..6878)
                     /locus_tag="IRB70_002650"
     CDS             complement(4818..6878)
                     /locus_tag="IRB70_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001286072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632548.1"
                     /translation="MSDVFSLAPEGQAWIDDKTVANPARPEDYDPTPFQGSGTALLSG
                     VAEGALGLAQSAVGFSKRLISDPAFTADVAPTVNIFREMFPDADKTLNDTYDTIGKQL
                     QDARSYVKPDAGSQGMAAEVLNELGKFVPAIGTTMFGGPLIGAATAFSSTYEQSYQDF
                     KGKGVDEATARNLATQQSLFNAVGMALPAAVGTTLATRIASGVAINTGFGGLNRYSVG
                     ATLEEKGYTEMAKQYRVFDGQAMLVDAVLGGVFGGVHHLTTHNNHDGTESNISAEEIK
                     STFGEHYQQSPDGNIESMVRDLSDSGVIELINEPAIKNSDGEILLNKGHVTVASGKEP
                     IIRININGLKDHEELLETLHHEALHLEQRHYPDWKARKLANAVLKSANKHSDYPEFAY
                     GMSQYYEYKKRGEYPETYPEWLYAEEVAAHAVNPSLKTSVSSWEKIISGFKAYIFRYS
                     GIQVGTVTPEQLRLLVSMRLRNMKLEAAVEKVFGIRARERIKPSDIDAAHILNEGLHY
                     DIESSPVLHTSNESINSHVDAMDEAYRQLNDGQPVNVGGMARGLDGPLRSDISDTYQE
                     QYHEIQKVFEENGVRYETSSEPISESPVPRAESAFSSAGEHRGDVSVDPDTGQVLSSN
                     SYDLMAARDMAVANPELTIAHPETGNPTKLSDLLAELDEQIKTVQNESKVYSVAAACF
                     LRNP"
     gene            complement(6878..9409)
                     /locus_tag="IRB70_002651"
     CDS             complement(6878..9409)
                     /locus_tag="IRB70_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004152436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632549.1"
                     /translation="MPVVPTVSGRQVESRGVQSAGLQTFSQPGIGDAFVRAGAEAIDV
                     FGQAKQRANIALIQEASLKLSQTGSDLLNNPETGLLNLKGKNAIGKGHEYTQQFDAQI
                     EQLAMSLPDEQARNAFMQQAQQQRIQFATQAGRYEIGQINAYEEGQFQATLLNNGKNA
                     SALYGDNAAYILANTQTFQQIEDYGIAHGWSDEQIQAKKIEFKEATAKATAQNAIGAN
                     YLQVRQQNGELSDTAAGSRRAVADSGSSDRTRGIRNNNPGNLEYSKTNPWVGQTGDDG
                     RFAKFETPEHGIRALGRNLLSYQRQGYDTISEIINRWAPASDDNKTDAYIRAVCAQLG
                     VTPDQPLDASNPDTLKSLCKAIIHHEQGSQPYSDQQLAAGVSAALGLSQLPTKNKRYT
                     GVAWFDALSESDQASVLRQTDALARQQQAEYRTMLESRVRDATAAYMRGVEFPNPPGE
                     GEFIAAYGVREGNLRYTEFRNLQIAGQYIGSFRNMPTSSITAYVEQLRPDTGETGEGY
                     ASRAELFDRVSAAATKVITQRQNNPFSAAVEIGAYKPITSNNPDDITAEVANRFSSQE
                     SLRALGINAPLLNSEEAAALAQQVRGTQNVDQTIKLLQSMGEKLPAPAIRQVASVIAP
                     NSAATAYSALLLGTPDNQYDNTRPTIPYSQFIGYKPTMNKYDVAKVILSGDQLLNPTK
                     AMKNAGITPVQLPSEDKMKDAFDEQVGNAFARNPQLRQISYSLFKAAYAGIAYQSGDA
                     STVRTSMPDTDIVADAVKYATGGIYNGFNGGDVVMPFGMDKSTFKDRYTTSAKQALKD
                     AGLNVNAVSNFTPVNIGNNRYRLVNGSGRWATDPRTNKAIVVRVE"
     gene            complement(9506..9712)
                     /locus_tag="IRB70_002652"
     CDS             complement(9506..9712)
                     /locus_tag="IRB70_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000995640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632550.1"
                     /translation="MNCINDLNTGDVRGGSVHLDAQTVMRLKQYRIDHVNNHPDQPLP
                     GVAQIVRHAVNAWLNQNGFASGGE"
     gene            complement(9844..10033)
                     /locus_tag="IRB70_002653"
                     /pseudo
     CDS             complement(9844..10033)
                     /locus_tag="IRB70_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577512.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
     gene            complement(10078..10494)
                     /locus_tag="IRB70_002654"
     CDS             complement(10078..10494)
                     /locus_tag="IRB70_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001580975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632551.1"
                     /translation="MEIVRNDHAHGRRAGDHIVDEIAEKQRVDIVVSVTVESAKRQNK
                     RINDHSDVHGVITRLRQTFVTREEMIEAIDQHTACISVRDIPEIIANYFMITRRLYRR
                     KDKSTVNRLLMSDIREYLQERGYVNPPEQHYGRVGG"
     gene            complement(10475..10972)
                     /locus_tag="IRB70_002655"
     CDS             complement(10475..10972)
                     /locus_tag="IRB70_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000164222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ProQ/FinO family protein"
                     /protein_id="HBC0632552.1"
                     /translation="MTKLTINRKPKGIYGTPQKTAQAAQQQNKTTSAHKVMPDNQNTQ
                     QKLTGATPRRRMTKQQRKNRRRVNRLIELWPELFSPESPKPLKVGIFDDLIQDIAARG
                     ISLGQGTLRATLARYVQTPRYYRALVAGGARYDLKGQPCGEVTPLQQTHAGKLLEEMN
                     GNSKK"
     gene            complement(11009..11434)
                     /locus_tag="IRB70_002656"
     CDS             complement(11009..11434)
                     /locus_tag="IRB70_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001758993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBC0632553.1"
                     /translation="MTAQISAYGRLVADPQLKTTSKGTQMAMASMAVPLPCNQADDGT
                     ATMWLSVLAFGRQADALAKHHKGELVSVAGNMQVSRWTGQNGETRQGWQVIADSVISA
                     RTARPGGKKGQQGQATDALNRAKQQTGQHDDPYGDGIPF"
     gene            complement(11645..13771)
                     /locus_tag="IRB70_002657"
     CDS             complement(11645..13771)
                     /locus_tag="IRB70_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309609.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF927 domain-containing protein"
                     /protein_id="HBC0632554.1"
                     /translation="MKRAPNLKHQPKDKMTEVIIFAGSDAWAHAKEWSEWAGKHIAAD
                     DTHPVILGPEQLASLADTQIIDKGRYYVRIYRAGEISEQHLTQIATLLAVAGVKEARC
                     YRSFVDQQPEDWTPRMAGLKYDAERGNSLVINLPAKTNFTGNYDDELKPRVESRVDGV
                     FWVTPKVDKQSGEIIRPETWLCSPLELLGTGTIGKEHYRVMRWKKPANHEVITMAVPC
                     GGIGDRDGWRLLKDHGLNVTTNGKYRAILADWMQLSGNHEEWQLSTTTGWHFGAYIMP
                     DGSIIGESEKPILFTGKTAAVNGYSVAGTAEGWRDTVARLAGGNPSMMLGVAVSLSAP
                     LIGLVGADGFGVHLFEQSSAGKTTTQNIASSLWGEPDAQRLTWYGTALGIANEAEAHN
                     DGLLPLDEIGQAGNAREVSTSAYTLFNGSGKLQGAKDGGNREIKHWRTVAISTGEMDV
                     ETFLKTEGIKIKAGQLVRLLNVPMEKASQFHEYSTGKAHADALKDAWTENHGAAGREW
                     VKWLAGHQQEAKDAVRACRERWRNLIPESYGEQVHRVGERFAVLEAALVLSGHVTGWD
                     VQACRDAVQHNFNAWVKEFGTGNREFKQMVEQAEAFLSSFGFSRYLPYPNSDERDLPI
                     KDLAGYRKGSIRNEDDEFRFYTFPHVFEGEIAQGFNPSHFARALSAAGMLEAGGDRRY
                     KKKALGRIGGKQHIFYVLMFQPEAED"
     gene            complement(13768..14070)
                     /locus_tag="IRB70_002658"
     CDS             complement(13768..14070)
                     /locus_tag="IRB70_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000721275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HBC0632555.1"
                     /translation="MKKIKFTGLNASGQTHPKIRIGDIFRDKYGDSVVINSVYERHIT
                     YRRAGYDYDCVMPVHQFRRDFSLVCAVPRSKPTSKEKARANIQVIKNMINAFRGKK"
     gene            complement(14073..14330)
                     /locus_tag="IRB70_002659"
     CDS             complement(14073..14330)
                     /locus_tag="IRB70_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632556.1"
                     /translation="MRDERFILLEQKFSEAPKNEIDALLHIANMLKVATFLIVSNLEH
                     ETALDILNSAVDYSEYIAEDKYRQLPDLLAHKYKEEPHTGK"
     gene            complement(14323..14526)
                     /locus_tag="IRB70_002660"
     CDS             complement(14323..14526)
                     /locus_tag="IRB70_002660"
                     /inference="COORDINATES: protein motif:HMM:NF033153.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host cell division inhibitor Icd-like protein"
                     /protein_id="HBC0632557.1"
                     /translation="MLNHTTHPQGRDSHNLNKYIWRFIALSTAQPRVIHIEAASEQEA
                     RQQSPAGCVMVFTARIRQGEYYA"
     gene            14732..14929
                     /locus_tag="IRB70_002661"
     CDS             14732..14929
                     /locus_tag="IRB70_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000094456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3950 domain-containing protein"
                     /protein_id="HBC0632558.1"
                     /translation="MSSGNTNNKSAKKNIRFPHELIDGIDASVEQEKLTNPSANFSAW
                     VLDACGRKLKYEQRRKAKEQE"
     gene            14987..15184
                     /locus_tag="IRB70_002662"
     CDS             14987..15184
                     /locus_tag="IRB70_002662"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632559.1"
                     /translation="MTDKSLKKLSSSRKKQRKNAVSEQEQERFAPCAFVLEKFLKEYR
                     RTKMGSHTWKTSQYGDAKEQE"
     gene            complement(15353..15910)
                     /locus_tag="IRB70_002663"
     CDS             complement(15353..15910)
                     /locus_tag="IRB70_002663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001580982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HBC0632560.1"
                     /translation="MRKPVFYAGRTEISVIKFDDIQVRIVSINGEPWFVGADVCAALE
                     ISNVTDAVSVLDNDEVMTLALTEGHSGKRGGARSWNVVSESGFYKLIARSRKASTPGT
                     FAHRFSNWVFREVIPSIRKTGSYGVPFAMLNDFSKRQAAYQQEASKRGYRLQQCKEAK
                     DALEREERALWRKYQPDFLEGESNV"
     gene            complement(15903..16727)
                     /locus_tag="IRB70_002664"
     CDS             complement(15903..16727)
                     /locus_tag="IRB70_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001580984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antA/AntB antirepressor family protein"
                     /protein_id="HBC0632561.1"
                     /translation="MKLRKTPVQGQGFVRPENQNLQNFGEIIPVISGVIGGREAAVVS
                     AKALHKALGVGKDFSTWITDRISEYDFTIGYDYSVHKTISPNLGKSPNGEAYSKIKHS
                     GRPGKDYLLSVGMAKELAMIERTEQGRAVRQYFIKCEEELHKVAPVRSAALRRELKAR
                     ITVASYFKPMCAALEAYRAELGKNTLQHHYTTEANMLARIVLGGMTAKQWAQANGITG
                     EPRDHMSTLQLEHLSYLEQSNITLIELGQDYHQRKAELIRLSQRWLARRMEVSSHA"
     gene            complement(16803..17000)
                     /locus_tag="IRB70_002665"
     CDS             complement(16803..17000)
                     /locus_tag="IRB70_002665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015462155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HBC0632562.1"
                     /translation="MSNTLIRLTEVQRRTGYSKAWIYRLMGQGKFPASVKIGSRAIAF
                     VESEIDEWINQRIAESRGTAA"
     gene            complement(17228..18025)
                     /locus_tag="IRB70_002666"
     CDS             complement(17228..18025)
                     /locus_tag="IRB70_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632563.1"
                     /translation="MIDIHAELNEYKKDFISLREFLEVVLKVAGDDYDVSDLITWILR
                     RISGEHIRLYTVNEFKLLESFCNPYRDEFDYDVLYRNLDAVRKHGCLPGERDENGFLV
                     SGYWEDPEFENIGFIRGEIFAIFPDVLDALTKLEGANSSENDEVQGRDIEKKELRTED
                     DLLSQIAMLERENAELRARIEQLEQERPIHLYKYWDKDPLAKAIEIRNREWANYDPEN
                     DFATRGNQEAITRELKQWGASNALATLIERTACPINRDNSQKNAKPD"
     gene            complement(18154..19368)
                     /locus_tag="IRB70_002667"
     CDS             complement(18154..19368)
                     /locus_tag="IRB70_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001603436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBC0632564.1"
                     /translation="MLLSDLAIRRAKPKEKAYTLNDGNGLSLLIEPNGSKGWRLRYRF
                     AGKPKMLSLGVYPDVSLSDARAARDEAKRLLAGGINPSEARKAQKREQASKFGNTFEG
                     IAREWYEKRIDRWSSSYAEEMIETFEKDVFPYIGGRPIAEIKPMELLAVLSRLNDRGA
                     TEKLRKVRQRCGEVFRYAIITGRAEYNPAPDLASAFAPHKKEHYAYLKADELPEFFRV
                     LNTYTGSQIVKLGMRLLILTGLRPGELRQAEWQEIDFDNRLWEVPKERMKMRRPHCVP
                     LSEQAIAILEQLKHMTGQYQFIFPGRIQHSKPMSEMAMNVLIRRIGYSGRVTGHGFRH
                     TMSTILHEQGYNTAWIETQLAHVDKNSIRGTYNHAQYLDGRREMLQWYADYMDSLEQG
                     GNVVHGKFGKCG"
     gene            complement(19533..19606)
                     /locus_tag="IRB70_002668"
     tRNA            complement(19533..19606)
                     /locus_tag="IRB70_002668"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19572..19574),aa:Gly,seq:ccc)
     gene            complement(19685..20437)
                     /locus_tag="IRB70_002669"
     CDS             complement(19685..20437)
                     /locus_tag="IRB70_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311765.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBC0632565.1"
                     /translation="MSAGRLNKKSLGIVMLLSVGLLLAGCSGSKSSDTGTYSGSVYTV
                     KRGDTLYRISRTTGTSVKELARLNGISPPYTIEVGQKLKLGGAKSSSTRKSTAKSTTK
                     TASVTPSSAVPKSSWPPVGQRCWLWPTTGKVIMPYSTADGGNKGIDISAPRGTPIYAA
                     GAGKVVYVGNQLRGYGNLIMIKHSEDYITAYAHNDTMLVNNGQSVKAGQKIATMGSTD
                     AASVRLHFQIRYRATAIDPLRYLPPQGSKPKC"
     gene            complement(20434..20610)
                     /locus_tag="IRB70_002670"
     CDS             complement(20434..20610)
                     /locus_tag="IRB70_002670"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632566.1"
                     /translation="MSQEIRYLYSEYFADDTSLCQMKLTSFSITAFFQKQEIGYQEAG
                     CYDMASCFLSEERF"
     gene            20853..23150
                     /gene="xdhA"
                     /locus_tag="IRB70_002671"
     CDS             20853..23150
                     /gene="xdhA"
                     /locus_tag="IRB70_002671"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase molybdenum-binding
                     subunit XdhA"
                     /protein_id="HBC0632567.1"
                     /translation="MEAREATATGESCMRVDAIAKVTGRARYTDDYVMAGMCYAKYVR
                     SPIAHGYAVSINDEQARSLPGVLAIFTWEDVPDIPFATAGHAWTLDENKRDTADRALL
                     TRHVRHHGDAVAIVVARDELTAEKAAQLVSIEWQELPVITTPEAALADDAEPIHNGGN
                     LLKQSTMSTGNVQQTIDAADYQVQGHYQTPVIQHCHMESVTSLAWMEDDSRITIVSST
                     QIPHIVRRVVGQALNIPWSCVRVIKPFVGGGFGNKQDVLEEPMAAFLTSKLGGIPVKV
                     SLSREECFLATRTRHAFTIDGQMGVNRDGTLKGYSLDVLSNTGAYASHGHSIASAGGN
                     KVAYLYPRCAYAYSSKTCYTNLPSAGAMRGYGAPQVVFAVESMLDDAATALGIDPVEI
                     RLRNAAREGDANPLTGKRIYSAGLPECLEKGRKIFEWEKRRAECQNQKGNLRRGVGVA
                     CFSYTSNTWPVGVEIAGARLLMNQDGTINVQSGATEIGQGADTVFSQMVAETVGVPVS
                     DVRVISTQDTDVTPFDPGAFASRQSYVAAPALRSAALLLKEKIIAHAAVMLHQSAMNL
                     TLIKGHIVLIERPEEPLMSLKDLAMDAFYHPERGGQLSAESSIKTTTNPPAFGCTFVD
                     LTVDIALCKVTINRILNVHDSGHILNPLLAEGQVHGGMGMGIGWALFEEMIIDAKSGV
                     VRNPNLLDYKMPTMPDLPQLESAFVEINEPQSAYGHKSLGEPPIIPVAAAIRNAVKMA
                     TGVAINTLPLTPKRLYEEFHLAGLI"
     gene            23161..24039
                     /gene="xdhB"
                     /locus_tag="IRB70_002672"
     CDS             23161..24039
                     /gene="xdhB"
                     /locus_tag="IRB70_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase FAD-binding subunit XdhB"
                     /protein_id="HBC0632568.1"
                     /translation="MFDFTSYHRAATLADAINLLADNPQAKLLAGGTDVLIQLHHHND
                     RYRHIVDIHNLAELRGITLAEDGSLRIGSATTFTQLIEDPVTQRHLPALCAAASSIAG
                     PQIRNVATYGGNICNGATSADSATPTLIYDAKLEIHSPRGVRFVPINGFHTEPGKVSL
                     EHDEILVAFHFPPQPKEHAGSAHFKYAMRDAMDISTIGCAAHCRLDNGNFSELRLAFG
                     VAAPTPIRCQHAEQTAQNAPLNLQTLEAISESVLQDVAPRSSWRASKEFRLHLIQTMT
                     KKVISEAVAAAGGKLQ"
     gene            24036..24515
                     /gene="xdhC"
                     /locus_tag="IRB70_002673"
     CDS             24036..24515
                     /gene="xdhC"
                     /locus_tag="IRB70_002673"
                     /EC_number="1.17.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine dehydrogenase iron sulfur-binding
                     subunit XdhC"
                     /protein_id="HBC0632569.1"
                     /translation="MNHSETITIECTINGMPFQLHAAPGTPLSELLREQGLLSVKQGC
                     CVGECGACTVLVDGTAIDSCLYLAAWAEGKEIRTLEGEAKGGKLSHVQQAYAKSGAVQ
                     CGFCTPGLIMATTAMLAKPREKPLTITEIRRGLAGNLCRCTGYQMIVNTVLDCEKTK"
     gene            complement(24555..26333)
                     /locus_tag="IRB70_002674"
     CDS             complement(24555..26333)
                     /locus_tag="IRB70_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent transcriptional regulator"
                     /protein_id="HBC0632570.1"
                     /translation="MELATTQSVLMQIQPTIQRFARMLASVLQLEVEIVDENLCRVAG
                     TGAYGKFLGRQLSGNSRLLRHVLETKTEKVVTQSRFDPLCEGCDSKENCREKAFLGTP
                     VILQDRCVGVISLIAVTHEQQEHISDNLREFSDYVRHISTIFVSKLLEDQGPGDNISK
                     IFATMIDNMDQGVLVVDADNRVQFVNQTALKTLGVVQNNIIGKPVRFRPLTFESNFTH
                     GHMQHIVSWDDKSELIIGQLHNIQGRQLFLMAFHQSHTSFSVANAPDEPHIEQLVGEC
                     RVMRQLKRLISRIAPSPSSVMVVGESGTGKEVVARAIHKLSGRRNKPFIAINCAAIPE
                     QLLESELFGYVKGAFTGASANGKTGLIQAANTGTLFLDEIGDMPLMLQAKLLRAIEAR
                     EILPIGASSPIQVDIRIISATNQNLAQFIAEGKFREDLFYRLNVIPITLPPLRERQED
                     IELLVHYFLHLHTRRLGSVYPGIAPDVVEILRKHRWPGNLRELSNLMEYLVNVVPSGE
                     VIDSTLLPPNLLNNGTTEQSDVTEVSEAHLSLDDAGGTALEEMEKQMIREALSRHNSK
                     KEVADELGIGIATLYRKIKKYELLNT"
     gene            26812..27999
                     /gene="ygeW"
                     /locus_tag="IRB70_002675"
     CDS             26812..27999
                     /gene="ygeW"
                     /locus_tag="IRB70_002675"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311770.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="knotted carbamoyltransferase YgeW"
                     /protein_id="HBC0632571.1"
                     /translation="MKTVNELIKDINSLTSHLHEKDFLLTWEQTPDELKQVLDVAAAL
                     KALRAENISTKVFNSGLGISVFRDNSTRTRFSYASALNLLGLAQQDLDEGKSQIAHGE
                     TVRETANMISFCADAIGIRDDMYLGAGNAYMREVGAALDDGYKQGVLPQRPALVNLQC
                     DIDHPTQSMADLAWLREHFGSLENLKGKKIAMTWAYSPSYGKPLSVPQGIIGLMTRFG
                     MDVTLAHPEGYDLIPDVVEVAKNNAKASGGSFRQVTSMEEAFKDADIVYPKSWAPYKV
                     MEERTELLRANDHEGLKALEKQCLAQNAQHKDWHCTEEMMELTRDGEALYMHCLPADI
                     SGVSCKEGEVTEGVFEKYRIATYKEASWKPYIIAAMILSRKYAKPGALLEQLLKEAQE
                     RVK"
     gene            28057..29253
                     /gene="dpaL"
                     /locus_tag="IRB70_002676"
     CDS             28057..29253
                     /gene="dpaL"
                     /locus_tag="IRB70_002676"
                     /EC_number="4.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopropionate ammonia-lyase"
                     /protein_id="HBC0632572.1"
                     /translation="MSVFSLKIDIADNKFFNGETSPLFSQSQAKLARQFHQKIAGYRP
                     TPLCALDDLANLFGVKKILVKDESKRFGLNAFKMLGGAYAIAQLLCEKYHLDIETLSF
                     EHLKNAIGEKMTFATTTDGNHGRGVAWAAQQLGQNAVIYMPKGSAQERVDAILNLGAE
                     CIVTDMNYDDTVRLTMQHAQQHGWEVVQDTAWEGYTKIPTWIMQGYATLADEAVEQMR
                     EMGVTPTHVLLQAGVGAMAGGVLGYLVDVYSPQNLHSIIVEPDKADCIYRSGVKGDIV
                     NVGGDMATIMAGLACGEPNPLGWEILRNCATQFISCQDSVAALGMRVLGNPYGNDPRI
                     ISGESGAVGLGVLAAVHYHPQRQSLMEKLALNKDAVVLVISTEGDTDVKHYREVVWEG
                     KHAVAP"
     gene            29311..30522
                     /locus_tag="IRB70_002677"
     CDS             29311..30522
                     /locus_tag="IRB70_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgeY family selenium metabolism-linked
                     hydrolase"
                     /protein_id="HBC0632573.1"
                     /translation="MAKNIPFKLILEKAKDYQADMTRFLRDMVAIPSESCDEKRVVHR
                     IKEEMEKVGFDKVEIDPMGNVLGYIGHGPRLVAMDAHIDTVGIGNIKNWDFDPYEGME
                     TDELIGGRGTSDQEGGMASMVYAGKIIKDLGLEDEYTLLVTGTVQEEDCDGLCWQYII
                     EQSGIRPEFVVSTEPTDCQVYRGQRGRMEIRIDVQGVSCHGSAPERGDNAIFKMGPIL
                     GELQELSQRLGYDEFLGKGTLTVSEIFFTSPSRCAVADSCAVSIDRRLTWGETWEGAL
                     DEIRALPAVQKANAVVSMYNYDRPSWTGLVYPTECYFPTWKVEEDHFTVKALVNAYEG
                     LFGKAPVVDKWTFSTNGVSIMGRHGIPVIGFGPGKEPEAHAPNEKTWKSHLVTCAAMY
                     AAIPLSWLATE"
     gene            30575..31960
                     /gene="hyuA"
                     /locus_tag="IRB70_002678"
     CDS             30575..31960
                     /gene="hyuA"
                     /locus_tag="IRB70_002678"
                     /EC_number="3.5.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311773.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-phenylhydantoinase"
                     /protein_id="HBC0632574.1"
                     /translation="MRVLIKNGTVVNADGQAKQDLLIESGIVRQLGNNISPQLPYEEI
                     DATGCYVFPGGVDVHTHFNIDVGIARSCDDFFTGTRAAACGGTTTIIDHMGFGPNGCR
                     LRHQLEVYRGYAAHKAVIDYSFHGVIQHINHAILDEIPMMVEEGLSSFKLYLTYQYKL
                     NDDEVLQALRRLHESGALTTVHPENDAAIASKRAEFIAAGLTAPRYHALSRPLECEAE
                     AIARMINLAQIAGNAPLYIVHLSNGLGLDYLRLARANHQPVWVETCPQYLLLDERSYD
                     TEDGMKFILSPPLRNVREQDKLWCGISDGAIDVVATDHCTFSMAQRLQISKGDFSRCP
                     NGLPGVENRMQLLFSSGVMTGRISPERFVELTSAMPARLFGLWPQKGLLAPGSDGDVV
                     IIDPRQSQQIQHRHLHDNADYSPWEGFTCQGAIVRTLSRGETIFCDGTFTGKAGRGRF
                     LRRKPFVPPVL"
     gene            32008..32940
                     /gene="arcC"
                     /locus_tag="IRB70_002679"
     CDS             32008..32940
                     /gene="arcC"
                     /locus_tag="IRB70_002679"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBC0632575.1"
                     /translation="MSKKIVLALGGNALGDDLAGQMKAVKITSQAIVDLIAQGHEVIV
                     THGNGPQVGMINQAFEAAAKTEAHSPMLPMSVCVALSQGYIGYDLQNALREELLSRGI
                     NKPVATLVTQVEVDANDPAFLNPTKPIGSFFTEQEAEQLTKQGYTLKEDAGRGYRRVV
                     ASPKPVDIIEKETVKALVEAGQVVITVGGGGIPVIREGNHLRGASAVIDKDWASARLA
                     EMIDADMLIILTAVEKVAINFGKENEQWLDRLSLSDAERFIEEGHFAKGSMLPKVEAA
                     ASFARSRAGREALITVLSKAKEGIEGKTGTVICQ"
     gene            complement(32981..34606)
                     /locus_tag="IRB70_002680"
     CDS             complement(32981..34606)
                     /locus_tag="IRB70_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EF2563 family selenium-dependent molybdenum
                     hydroxylase system protein"
                     /protein_id="HBC0632576.1"
                     /translation="MNIFTEAAKLEEQNCPFAMAQIVDSRGSTPRHSAQMLVRADGSI
                     VGTIGGGMVERKVIEESLQALQERKPRLFHGRMARNGADAVGSDCGGAMSVFISVHGM
                     RPRLVLIGAGHVNRAIAQSAALLGFDIAVADIYRESLNPELFPPSTTLLYAESFGAAV
                     EALDIRPDNFVLIATNNQDREALDKLIEQPIAWLGLLASRRKVQLFLRQLREKGVAEE
                     HIARLHAPVGYNIGAETPQEIAISVLAEILQVKNNAPGGLMMKPSHPSGHQLVVIRGA
                     GDIASGVALRLYHAGFKVIMLEVEKPTVIRCTVAFAQAVFDGEMTVEGVTARLATSSA
                     EAMKLTERGFIPVMVDPTCSLLDELKPLCVVDAILAKQNLGTRADMAPVTIALGPGFT
                     AGKDCHAVIETNRGHWLGQVIYSGCAQENTGVPGNIMGHTTRRVIRAPAAGIMRSNVK
                     LGDLVKEGDVIAWIGEHEIKAPLTGMVRGLLNDGLAVVGGFKIGDIDPRGETADFTSV
                     SDKARAIGGGVLEALMMLMHQGVKATKEVLEVA"
     gene            complement(34654..35424)
                     /gene="yqeC"
                     /locus_tag="IRB70_002681"
     CDS             complement(34654..35424)
                     /gene="yqeC"
                     /locus_tag="IRB70_002681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417352.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium-dependent hydroxylase
                     accessory protein YqeC"
                     /protein_id="HBC0632577.1"
                     /translation="MKSIIDPSALFIDLGAQKRPTVISVVGAGGKTSLLFWLAELFQA
                     SGRRVLITTTTHMFMPTSHWPVVFCRDPAMLPHASFISPISFCFHSWKANQGKVQGFT
                     PEAIDALVQRPECDVILIEADGSRGMPLKAPDEHEPCIPKSSCCVIAVMGGHILGAKV
                     STENVHRWSQFADITGLTPDAPLQLSDLVALVRHPQGAFKNVPQGCRRVWFINRFSQC
                     ENAIAQSELLQPLQQHNVEAIWLGDIQEHPAIARRFVN"
     gene            35528..>36100
                     /gene="mocA"
                     /locus_tag="IRB70_002682"
     CDS             35528..>36100
                     /gene="mocA"
                     /locus_tag="IRB70_002682"
                     /EC_number="2.7.7.76"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor cytidylyltransferase"
                     /protein_id="HBC0632578.1"
                     /translation="MSAIDCIITAAGLSSRMGQWKMMLPWQQGTILDASIKNALQFCS
                     RIILVTGYRGNELHERYANQSNITIIHNPDYAQGLLTSVKAAVPAVQTEHCFLTHGDM
                     PTLTIDIFRKIWPLRNDGAILPLHNGIPGHPILVSKPCLMQAIQRPNVTNMRQALLMG
                     EHYSVEIENAEIILDIDTPDDFITAKKRYTE"
BASE COUNT         8895 a         9405 c         8329 g         9471 t
ORIGIN      
        1 ttaacgataa ataactttta tcagttgctg cccccgtgga attaagaatg ttaaatacag
       61 attcactcgt cacttctgcc cctgtcgcct ggcatgtgcc gcacgaaaat ataccagcga
      121 gcagaagagt taatgtagat ttccctttca taaaagattc catcaatcgt ttgttaaaag
      181 cgtagataac cacttattta acaacttgaa aataaggtat tttacctggg ttgttacaaa
      241 aggattgcat tgcgtaaacg ctttttattt acaaaaaaat ggggaagtgt tacagcgatt
      301 gcgaaaagtc tgaagcaatt gaattaagat aatatagaaa gtcagataca gcaaaaatgg
      361 caggttgatg aggtgaagat aaattggagc gggcgaaggg aacaatacaa catcacacaa
      421 ggccagtaat agcgcgaatc ctgcgagttc taaaatcaat tctatacaca tttctataca
      481 catttatccc tcgcttgagg gttatgcgtc atcgttatcg gctatctcgc tggtggatga
      541 tcacggatgg cctgatatct acagccgcct taaaaagctg tacccgacaa gcattactgc
      601 gtatcgggtt cgttcgctct ttctactcgt ggcagatgag tttatcggtg tgattttatc
      661 gggcgagggt attgtatcag gcatcccctt ttctatgcag atttgcatag ttccgaatgg
      721 tggcgttatg gaagcctccc atatcagcat catgcccacc agcgtgaagt atttttttat
      781 ttcgcgggtg taaaaatttg acgaggcggg cggtcccata agcaatggat tgtagggatt
      841 tcgctccccc cctcctgaat gcaatttttc gtatatatat acaaaacagt gcgggttatg
      901 cgggttaccg ggttatctta gtatgctaac tattttttgt tctttagtat caatatgttg
      961 caaaatacac tgttcattat tcaagcatca cataacccgc aaaacatccc aaataacccg
     1021 caaacgcccc aaaataaccc gcaaacacat tgctgaaagc aggggttgat agttccactg
     1081 gtgccacaga acggctgaat acggtaactg ttgctggtgg tctgtcctgt tgtcgttcca
     1141 gtctcatcaa attgagaggc aagacaaagt gtatttttgc actatagcca aagcctcata
     1201 aaacagagtt acccccacag gctggcaaaa accattaccc aacgcaatta agtgcgtcag
     1261 aatcgattac agcgcgttcc tgtggcacgt tgttgccgtt ctcagcagtg aaaggagagc
     1321 gtgaaaagct catatctatt actgttgagg ggtgtagcgg catatatcgc gaatatccac
     1381 gcccttaatc ccgataccgt cactacgcat tgagatccac cagaagatta agatagtttt
     1441 acctgaaatt atccaaataa ttgttttaac tgattaattt ttcgaatatc tattgttagg
     1501 gaataaatca tcagatacac cataaaacga catctttcag ggtgtagaag atgcaaagcc
     1561 gatactgaag aaaagacaaa gaatatgaat ggctggccac acgatggaag gattgtccat
     1621 tgaaggatca atcctaatgg tataagtatt aataaaaccg tgcagcgtgc ttttttatct
     1681 gcgaattccc gcccgggcgg cggtggcatt cgttaaaaac aaggccgcga aagcggcctg
     1741 tgacatgtca cgatagttcc gttttgttga attcaattat atcaaggtca gaactttcgt
     1801 aatccttacc gaataaagca aaacatatcg cgtcaagttc tctcttatgt ttggacgccc
     1861 gatcataatt accaccccaa cagcaaatga atccaccaag tactgctgat tcaaaaagta
     1921 atgatgctgc atcaatatgt ctgaaccagg agtctataag taaagcagag agtgatatta
     1981 atgttcccca cccgccaatc cttctccatt tctcagcttc atatttaaga gaagcaatat
     2041 attcaatttt atctctcgtc atcagttccc caccgccttt ccaaaatccg gtgctctacg
     2101 tggcgcaata gcacccggtt cccaccaact cgttatgtcg aactcccgtt gcgcgcggtc
     2161 ccttactcga tcattgtaac cagggtttgc catctcctga agttgttgca atatcaggtg
     2221 attggttatc gctttcgcat accacaggtt tgcgaatggg gtgatcatgc gggctgtttt
     2281 cagtgcatcg gcaccgaatg atgtttcttc accctgtaga gccttctgtg ggttagtaat
     2341 cagtaatttt gttaactgct ctgcaaagct caacacaggg ccacccatag tggcaccgat
     2401 gctggagcca tattgcgtat ggtcctggaa aataaaatca ccgtagatac cgaacgaacc
     2461 acctttcagt aaagcctgaa cccatgtggt tggttttgtc atatccagcg gatcattacc
     2521 atttaacaaa ctgttcatct ggatcgcaaa cataccagca agagttgttc ccccgatata
     2581 tgaggccaga aatttaatgg ccggaacggt gtccaaatcc cgtgttctgt taacaagttg
     2641 ccgaaatcca gcaaatgggg ttgttttgaa gagcatgaag ctcttcatta actcgccagc
     2701 atcatcacgg gcatatgtat caatacccgt agcggtggtc acagcattgg tcatctcacc
     2761 gtgcgtaatt cccagcaatt tatgggctgc ttcagcgcgt gcattacgaa tcatgcgcgt
     2821 gatggtctgc tcagcctcag cgtcgaatgc ttctttcatc cgtttcaggc gttctggagg
     2881 gagatctcca agtgctgcca gtgccttttc actcccggca cgaatccggg taatacggtc
     2941 tgccataatg tcggcgatta cgttatcggg cacagcgtaa atcgcgtctg gcgtcatccc
     3001 catatgcccg gcagtagtca tcggcctgag ttctgccgct gccatgatgg cccagtcctc
     3061 attgctccat cccttgttag ccagaatggt tttatcggtt cctttcatat cgtccagcgt
     3121 cttaaatttt ctggtcagct cgccaatgtt tttgtacatc aggagaccaa acgacgcttt
     3181 gtttgcgcgg tccatagcga tcagcccgga ccacttcagt gtcttctctg cgaaccagcc
     3241 agttatgccg cgagacaagt caaacccgcc cattttcgaa accacagcag catgtgaatc
     3301 caccagcaga ccgagttcag cattcgcctt tttggcatct ccactaaaca ggtttttgat
     3361 agtgttaacg gaaagccgca ttccaccacg ggtaaagccc agcgcctgcg catttgcccg
     3421 cataattgcc tggtcgctgg ttgctgtcag tacgctggtg ccaagcatgg cgctggtcat
     3481 caggttacgc agaccaccaa cagctgaaga gaacacactc gatgaagcga caccatttag
     3541 gccagccatt gagttgaaca tacgggctac taatttggcc tcatcctcca tttctttttt
     3601 gcgtttcccg cctgttactg cgcgcttata gatgcgatcc agtaccaggg aaaagtttct
     3661 ttcggcgtcc ggaccaaagg ctttaacgac gcccaaatcc ctggatgatg attgcaggtg
     3721 cgacatcatc acccccacca gcggctgctg agtgtatcgc tccatatagg cgaagtgtga
     3781 ctgcgcatcc ttgaacgcca tcaccctgtg ctgagaacca cggctcttta ttcctccggc
     3841 tcccataaat gtaccgggct caattttgtt tgccccatca gtggccttcg tttcaaagat
     3901 cgcttccagt gcctgacggt actcgacgtc attcataatg ctgccgtcag gattaacgta
     3961 attgctgcga tcctgcgtgt tgtaagcgtc atcaacccat ttctggcggg caaactcaat
     4021 cggtggctgg cgacctgaaa gacgtgctgt agcttgctct gccactggta acgatgccag
     4081 ccattcttcg cgcccggcat tgcgaataag gtcagcatca tccacatatg gcgtatgcca
     4141 gtcttctcgc aggcctatgt caaagccgtt gtcgttcatc tcatgacgaa cacggcctgt
     4201 tacatccttc caaatctgtg caattttctt cgccagggga ttcccggtat cttcgccata
     4261 aatttctttc aggatctgga gttgtgcaga ctttgccgcc tgcctgtcga atacactccg
     4321 aaaccgctgc tctccaagcg ccctgctctg ctcgaagaat ttgcggacgt catcacctgc
     4381 ttttagaagt tcagcactga gctgacggga ccagtcctga tatgccccaa ttgcaagctc
     4441 ttcagcagaa gcaacggaga tatcagcttt gtctctcgat cgtcggccag caaaaataaa
     4501 ctgctgcaaa ttaacaggtg tctgctgatc aggcgggatg ttagcatcga gagtgtcagt
     4561 aattttactg atggcgatcg cattctgggc aacacgctgt cttttcttgt acacatcatg
     4621 aaccacacgc tggcgtacca gttctgcagc atccatgtat gtttgagcat caggaatacc
     4681 acttttgcct tcttttgcat tctttctgtg cacatgttgc actgcttctt tgatacgatc
     4741 ttcgatattt ttcagctcat cagcctttgg ctggcgacca agtgtctgcg caatagcttc
     4801 aacacatgcc tgtttcatta tgggttcctc aagaagcacg ctgccgctac agaataaacc
     4861 ttcgattcgt tctggactgt cttaatctgt tcatccaact cagccaggag atcagaaagt
     4921 tttgtcgggt ttccggtttc cgggtgagct atagtcagct caggattggc aacagccatg
     4981 tctctggcag ccataaggtc atagctgttg gatgagagaa cctgccctgt atctggatca
     5041 acgctgacgt cccctctgtg ttcaccagcc gatgagaaag cactttcagc acgagggaca
     5101 ggcgattcac taattggctc tgatgatgtt tcatatctga caccattttc ttcaaaaacc
     5161 ttttgtattt catggtattg ctcttggtaa gtatcagata tatctgatcg caatggacca
     5221 tcaagccctc gcgccatccc cccaacattt acaggctgac catcattaag ttgcctgtat
     5281 gcttcatcca tggcgtcaac atggctgttg atgctctcat tgctggtatg aagcactggt
     5341 gacgattcaa tatcgtaatg aagcccctca ttcaaaatgt gggctgcatc aatatcgctt
     5401 ggttttattc tttccctcgc ccggatacca aaaacttttt ctactgcggc ttccagtttc
     5461 atattgcgaa gacgcatact tacgagtaac cgtaactgct caggtgtaac ggttccaacc
     5521 tgaataccac tgtatctgaa tatataggct ttaaaacctg aaataatttt ttcccatgat
     5581 gaaacgcttg tctttagaga tggatttact gcatgtgcgg caacttcttc agcgtacaac
     5641 cactcaggat atgtttcagg gtactcaccc cttttcttat attcataata ttgtgacatc
     5701 ccatatgcaa attcaggata gtcagaatgc ttgtttgcag atttaagtac agcattagct
     5761 agctttctgg ccttccagtc agggtaatgg cgctgctcaa gatgaagcgc ctcgtgatga
     5821 agggtttcta acagttcttc atggtctttt aatccattaa tatttattct tattattggt
     5881 tcttttccgg aagctactgt cacatgacct ttattcagaa gtatttctcc atcactattt
     5941 tttattgctg gttcattaat aagttctatt actcctgaat cagataaatc acgaaccatt
     6001 gactcaatgt taccatcagg agattgctga taatgttcac caaaagttga ttttatttct
     6061 tctgcagaaa tgttcgactc tgtaccatca tggttattat gggtagtcag gtgatgaacg
     6121 ccaccaaaga ccccgcctaa aacggcatcg actaacatcg cctgaccgtc aaatacccgg
     6181 tactgttttg ccatctccgt gtagcctttt tcctccagtg ttgcgcctac tgagtaacgg
     6241 ttcagtccac cgaatccggt gttgattgcc acacctgagg caatgcgcgt tgccagtgtg
     6301 gtgccgacgg cagcgggtaa ggccataccc acagcattga aaaggctctg ctgcgttgcc
     6361 aggttacgcg ctgtagcctc gtctactccc ttccctttaa aatcctgata ggactgctca
     6421 tacgtagaac tgaaggctgt agcagcgccg atgagcggac caccaaacat agttgttccg
     6481 attgcaggaa caaatttacc aagctcattt aatacctcag ccgccattcc ctggctgcct
     6541 gcatcaggct tcacatagct gcgggcatcc tgtaactgtt ttccgatcgt gtcgtatgta
     6601 tcattcagtg ttttgtcagc atcagggaac atctcccgaa aaatattaac tgtcggtgcc
     6661 acgtctgcgg taaatgccgg atcgctaatc agacgcttgc tgaatccgac ggcagactgc
     6721 gcgagaccga gagccccctc cgccacgccg ctcaaaagtg cagtacctga accctggaag
     6781 ggagtcggat cgtagtcttc tggccttgct gggttggcaa ctgttttgtc gtcaatccat
     6841 gcctgacctt ctggagccaa agaaaaaaca tcagacatta ttcaaccctc acgacaatag
     6901 ctttattggt tctgggatct gttgcccagc gtccgctacc atttacaagc cgataccggt
     6961 tattgccgat attaactggc gtgaaatttg acactgcatt tacgttaagt ccggcatctt
     7021 tcagtgcttg tttcgcagat gtggtatagc gatctttgaa agtagattta tccatgccaa
     7081 aaggcattac aacgtcgccg ccattaaaac cattgtatat accgccagta gcatacttca
     7141 cggcatcagc tacaatgtct gtatcaggca tactggttct taccgtagag gcatcaccag
     7201 attgataagc tattcctgcg taagcggctt tgaaaaggct ataactgatc tggcgtaact
     7261 gcgggttacg ggcaaatgca ttacctacct gttcgtcgaa agcgtctttc atcttatctt
     7321 cgctcggcaa ctgtaccgga gttatgcccg cattcttcat ggccttcgtc ggattcagta
     7381 gttggtcgcc ggaaagaata acctttgcaa cgtcgtactt gttcatcgtc ggcttatacc
     7441 cgatgaactg actatatggg atcgtcggcc tggtgttgtc gtactggtta tccggcgtgc
     7501 ccagcagcag cgcagaatag gctgttgccg cactgttcgg agcaattaca gatgccacct
     7561 gccgtattgc tggcgcaggc agcttctccc ccatgctctg caacagttta attgtctggt
     7621 caacgttctg agtgccgcgc acctgctgtg ccagcgcagc cgcctcttca ctgttgagga
     7681 gtggggcatt aattcccaac gcgcgtaagc tttcctgcga cgagaaacgg ttagccacct
     7741 cggcagtgat gtcgtcaggg ttgttgctgg tgatcggctt ataggctccg atttccaccg
     7801 ctgcactaaa cggattattc tgcctctggg ttattacctt cgtggctgcc gccgataccc
     7861 ggtcgaataa ctccgcacga gacgcatacc cctcccctgt ctcaccagta tccgggcgta
     7921 attgctcaac atatgcggta atgctgcttg tcggcatgtt gcggaaagag cctatatact
     7981 gtccggcgat ctgcaaattt ctgaactcgg tatatcgcag gtttccttct ctgacaccat
     8041 aagcagcaat gaactcaccc tcaccaggcg ggttaggaaa ttcaacgcca cgcatatacg
     8101 cagccgttgc atcgcgaacc cggctttcga gcatcgttct atattcagcc tgctgctgtc
     8161 tggctaatgc atccgtctgt cgcaacacgc tggcctgatc tgattcactt aaagcatcga
     8221 accaggctac accggtataa cgtttatttt ttgtcggtag ctgagaaagc cccagtgcgg
     8281 cactaacgcc agcggccaat tgctgatcac tgtacggctg actgccttgc tcatgatgaa
     8341 taattgcttt gcacagagat ttcagtgtgt caggatttga tgcgtcaagc ggctggtcag
     8401 gagttacacc gagctgagca catactgccc gtatataagc atcagtttta ttatcatcac
     8461 tggccggtgc ccagcgatta attatttcgc tgatggtgtc ataaccctga cgctgatacg
     8521 acagcaaatt gcgaccaagc gcgcgaatac cgtgttcagg ggtttcgaat ttggcaaagc
     8581 gaccatcatc accagtctgc ccaacccacg gattagtttt gctgtattca agattgccgg
     8641 ggttattgtt gcgtataccg cgggtacgat cggaagagcc actatctgct acagcacggc
     8701 gagatccagc agcagtatcg cttaactcgc cattttgctg tcttacctga agatagtttg
     8761 ctccaatagc attttgagca gttgcttttg ctgttgcttc tttaaactcg attttcttgg
     8821 cctggatttg ctcgtcgctc cagccatgcg caataccgta atcctcaatt tgctggaaag
     8881 tttgcgtatt agccaatatg tatgctgcgt tgtcgccata taatgctgag gcatttttac
     8941 cattattcag cagtgtcgcc tgaaactggc cttcttcgta ggcatttatt tgccctatct
     9001 cgtacctccc ggcctgcgta gcgaactgaa tacgctgctg ctgcgcctgc tgcatgaaag
     9061 cattacgagc ctgttcatcc ggcagcgaca tagccagttg ttcgatctga gcatcaaact
     9121 gctgtgtata ctcatggcct tttccaatag catttttccc tttcaggtta agcaatcctg
     9181 tttcaggatt attcagcaga tcactgcctg tctgactgag tttaagggat gcctcctgaa
     9241 tcaaggcaat attggcacgc tgttttgcct gaccaaaaac atcaattgcc tctgcccctg
     9301 cccgaacaaa agcatcacca atacctggct gagaaaacgt ctgcaagcct gctgactgaa
     9361 ctccacggct ctcaacctga cgtccggata ctgttggtac gactggcatt agtaacctcc
     9421 tattttgaat cgggagtcag aattcataaa acctgagtta gataacattg gcgtccctct
     9481 gctttgatgc tgtaccagcg attcattact caccccccga tgcaaaacca ttctgattaa
     9541 gccaggcgtt tacggcatgt ctgacaatct gcgccacgcc tggtaatggc tgatcagggt
     9601 gattgttcac atggtcgatt ctgtactgct taaggcgcat cacggtctgt gcatccagat
     9661 gaacggaacc acctctgaca tcgcctgtgt tcaggtcgtt aatacaattc acagcaattt
     9721 cctcttaatg actaaattat gcacattatt gatcgaaaaa agtggtagat aaatatattt
     9781 ctatcacaaa aatagattga ttgatttcag ccaaaaaaaa gccggattgc tccggctctg
     9841 tgcttacttc tggtagttac gccatactga tttcccgatc ccatctatcc ccatttcttt
     9901 ttcagtgcgt ttaagcgacc gtttcaggtc ttctaaatta tccggttgct tcggtggcct
     9961 ctgtgccttc ctggaacatt ccagtcgtcg cattgatatg taataccgtt ccttgtcagt
    10021 tccccaactg cattacttca ccccatcgcg ccgccgctct tcggtacagg gttttagtta
    10081 gcctccgact cttccgtagt gctgttctgg tggattcaca tagccccttt cttgcaggta
    10141 ttcgcgaata tcagacatca ggagacggtt aaccgtgctc ttgtcttttc tccggtaaag
    10201 gcgtctggtg atcatgaagt agttagcaat gatctctggt atatccctga cgctgataca
    10261 tgctgtatgc tggtcaatag cttcaatcat ctcttcacga gttacaaaag tctggcgtaa
    10321 acgagtgatc acaccatgta catctgaatg atcatttata cgcttatttt ggcgcttcgc
    10381 gctctcgact gtgacactga caacaatgtc aactctttgt ttttccgcaa tttcatccac
    10441 aatgtgatca cctgcacggc gaccatgtgc gtgatcattt cttactattt ccattcatct
    10501 cctccagtag ttttcctgcg tgcgtctgtt gtagtggtgt tacctcgccg cacggctggc
    10561 ctttcaggtc gtaacgcgcg ccaccagcta ccagggcgcg gtaatagcgc ggagtctgca
    10621 cataacgcgc cagcgttgcg cgtagtgttc cctgtccgag tgaaatacct ctcgcggcaa
    10681 tatcctgtat caggtcgtca aatatcccca ccttaagcgg cttaggggat tccgggctga
    10741 ataattcagg ccatagctca ataagacggt taacgcgtct gcggttttta cgctgctgtt
    10801 tggtcatacg ccgccgcggt gttgctcctg tgagcttctg ctgtgtgttc tggttatctg
    10861 gcatcacttt atgcgccgat gtggttttat tctgctgctg cgccgcctgt gctgttttct
    10921 gcggcgtgcc gtaaatgccc ttcggttttc tgtttatggt cagctttgtc atgccttccc
    10981 ctgtaattac tctgttcgct gttgtgaatt aaaacggtat cccgtccccg tacggatcat
    11041 cgtgctggcc tgtctgttgc tttgccctgt tcagtgcatc agtagcctgc ccctgctggc
    11101 cttttttgcc gcccggtcgc gccgttcgcg cactgattac gctgtctgcg ataacctgcc
    11161 atccctgcct cgtttcgccg ttctggcccg tccaccggct cacctgcatg ttaccggcca
    11221 cgctcaccag ttcgcctttg tggtgttttg ccagtgcgtc agcctgtctg ccaaacgcca
    11281 ggacggataa ccacatcgtc gccgttccgt catctgcctg attgcatgga agggggaccg
    11341 ccatactcgc catcgccatt tgtgtgccct tgctggtggt ctttaactgc gggtcagcca
    11401 ccagccgccc gtaagctgat atttgcgccg tcatgctgtt tgttctccgg ttttaacgtg
    11461 atagttacgc ttgtttacac tcttacagtg aaattttgcg ggttacaatc gcacatttgc
    11521 gggttataac tgccgttttg cgggttacgt gcgggttatt gatttccttt ttaatcatgc
    11581 agttaattaa cttatacaca ggataacccg cataacccgc aactttttac ctcacacagg
    11641 gaagttaatc ttctgcttca ggctggaaca tcagcacgta aaaaatatgc tgcttcccgc
    11701 caatcctgcc gagcgccttt ttcttgtaac ggcggtcgcc tcccgcttcc agcattccgg
    11761 cagcactcaa cgcgcgggca aagtgagacg gattaaatcc ctgtgctatc tcaccctcaa
    11821 acacatgcgg gaacgtgtaa aaacggaact cgtcatcttc gtttctgata ctcccctttc
    11881 tgtatccggc aaggtcttta atcggtaaat cacgctcgtc gctgtttgga tagggaaggt
    11941 atcgactgaa cccgaacgac gacaaaaacg cctcagcctg ttcaaccatc tgtttaaatt
    12001 ccctgttgcc cgtgccgaat tccttcaccc aggcattaaa gttatgctga actgcatcac
    12061 ggcacgcctg aacatcccag cctgtaacat gaccggaaag cacaagcgcg gcctccagta
    12121 cggcgaatct ttcccccaca cggtgaacct gctcgccgta gctctccggt atcaggttgc
    12181 gccaccgctc gcgacatgcc cttaccgcgt cctttgcctc ctgctggtga cctgccagcc
    12241 atttaaccca ctcacgacct gccgccccgt gattttctgt ccaggcatct tttaacgcgt
    12301 ctgcgtgcgc ctttccggtg ctgtattcgt gaaactgcga tgccttttcc atcggcacgt
    12361 taagcagacg gacaagctgc cccgctttaa tttttatccc ttccgttttg aggaatgttt
    12421 caacgtccat ttctccggtg ctgattgcca ccgtgcgcca gtgttttatc tccctgttgc
    12481 cgccgtcctt cgccccctgt aatttcccgg aaccgttaaa cagcgtatag gctgacgtgg
    12541 acacctcccg tgcgtttccg gcctggccta tttcatccag gggtaacagc ccgtcattat
    12601 gtgcttcggc ctcgttggcg atacctaacg ccgttccgta ccaggtcagc cgttgcgcgt
    12661 ccggctctcc ccataaactt gatgcaatgt tctgtgtggt ggttttacct gctgatgatt
    12721 gctcaaaaag atgaaccccg aagccgtcag cacccaccag cccgattaat ggtgcagata
    12781 gcgataccgc cacacccagc atcatggacg gattaccacc agccagccgt gccacggtat
    12841 cgcgccagcc ctccgctgtt cccgccacgg aatagccatt aacagcggca gtttttccgg
    12901 taaacaggat gggtttctct gattcaccga tgatcgaacc atccggcatg atgtacgcac
    12961 caaaatgcca ccccgttgtt gtgcttaact gccattcctc atggtttccg cttaactgca
    13021 tccagtcagc caggatagcc ctgtatttgc cgttggtcgt cacgttaagg ccgtggtctt
    13081 tcagcaaccg ccagccgtca cggtcaccaa tgcctccgca cgggaccgcc attgtaatga
    13141 cctcatggtt tgctggtttt ttccagcgca tcacgcggta atgctctttg ccgattgttc
    13201 ctgttcccag tagttcaagc ggagaacata accacgtctc aggccggata atttcgcctg
    13261 actgcttgtc cactttgggc gttacccaga aaacaccatc gacgcgactt tcaacacgag
    13321 gctttaattc gtcatcataa tttccggtga aatttgtctt cgccggaagg ttgatcacca
    13381 gactgttacc gcgttccgca tcatacttca gtccagccat gcgcggagtc cagtcctccg
    13441 gctgctgatc aacaaagctg cggtagcaac gcgcctcctt cacacccgcc actgcaagca
    13501 gtgtcgctat ctgtgtaagg tgctgctctg atatttcacc agcacgataa atgcgcacgt
    13561 aatagcgtcc tttgtcgatg atttgcgtgt ctgccagact cgccagttgt tccggtccaa
    13621 gaataactgg atgtgtatca tctgccgcaa tatgctttcc ggcccattcg ctccactctt
    13681 tcgcatgtgc ccaggcatca ctacccgcaa agataatcac ctccgtcatt ttgtctttcg
    13741 gctggtgctt taaattcggt gcgcgtttca tttcttgccc ctgaatgcgt taatcatgtt
    13801 ctttattacc tgaatatttg cccgtgcttt ctctttactg gtgggcttac tgcgtggtac
    13861 tgcacatacc agtgaaaaat cacgccggaa ctgatgaacg ggcatcacac agtcatagtc
    13921 gtaccctgcg cggcggtatg taatgtgccg ttcatacacg gaattaataa ccacgctgtc
    13981 accatattta tcccggaaaa tatccccgat cctgattttc gggtgagtct gtccgctggc
    14041 atttaagcca gtaaatttaa tcttcttcat gtttatttcc cggtgtgagg ttcttcttta
    14101 tatttatggg ctaacaaatc tggtaattgc ctgtatttat cctcggcaat atattcagaa
    14161 taatcgacag cactgttcag tatatctaac gccgtttcat gctccagatt cgaaactata
    14221 aggaacgttg ctacttttag catattcgcg atatgcaaaa gagcatcaat ttcatttttt
    14281 ggcgcttcac tgaatttttg ctccagaaga ataaatcgtt catcacgcat agtattcccc
    14341 ctgacggatg cgggcagtaa ataccatcac gcagccagcc ggggattgct gacgggcttc
    14401 ctgttcgctg gcggcctcga tgtgtattac gcgtggttgt gcggtgctca gggcgataaa
    14461 acgccagatg tatttattca ggttgtgcga gtcccgccct tgcgggtgtg tggtatgatt
    14521 taacatagct acctcgatac gctttctatc gttggtggtt agacgccctg catgtgttgc
    14581 gagcactgcg gggcgttgct taatttgagc aatgcaaccc aaactgtgcg cacagattaa
    14641 aatcatgtgt gcgcacatgt caatacttaa cttctcactt tttttgctgt attgtgtgcg
    14701 cccatcaaat ccatttaagt gaggtgtacc aatgtctagc ggaaacacaa acaacaaatc
    14761 agcaaagaaa aatattcgat tcccgcacga gcttatagat gggattgatg ccagtgttga
    14821 acaagaaaaa ttaactaatc ctagtgctaa tttttccgca tgggtcttag atgcctgtgg
    14881 acgcaaatta aaatatgaac agcgccggaa ggccaaagag caggagtaac catcaccagc
    14941 gccgtggtgc ggtgaactgt ggcgcacagg gttacaggta tctacgatga ctgacaaatc
    15001 attaaagaaa ttatcctcat ccaggaaaaa acaacgcaaa aatgcggtaa gcgaacaaga
    15061 acaggaaaga tttgcgccat gtgcgtttgt ccttgagaag ttcttaaaag agtacaggcg
    15121 cacaaaaatg ggatcgcata cctggaaaac atcgcagtat ggcgatgcta aagagcagga
    15181 atagcccacc agcaagccag cacactgatc acattgccca ccagccgcaa atctggcatt
    15241 gttggcgatg cgtttgattt cctttgttcc cactggcgac ctatcccggt cgcctttgtt
    15301 ttgcctgtta tccagcaacg gggcgctttt tctttctgta acgttcggat cgttacacat
    15361 tgctttcacc ctccagaaaa tcaggctgat atttacgcca tagcgcccgc tcttctcgtt
    15421 ccagtgcatc ttttgcctct ttgcattgct gtaacctgta accgcgtttg ctggcttcct
    15481 gttgatatgc agcctggcgt ttactgaaat cattcagcat ggcaaacgga acaccataac
    15541 tccccgtttt gcggattgaa ggaataacct cgcggaatac ccagttactg aaacggtgcg
    15601 caaatgtgcc aggtgtggaa gctttacggc tgcgggcgat cagtttgtag aaacctgatt
    15661 cagagacaac attccagctt ctggcaccac cacgcttacc ggaatgcccc tcggttaaag
    15721 ctagggtcat tacctcgtcg ttatccagaa ctgaaacagc atcagtaaca ttgctgattt
    15781 ccagcgcagc acacacatca gcgccaacaa accacggctc gccgttgata ctcactatgc
    15841 gcacctgaat gtcatcgaat ttaatgacag agatttcagt gcgcccggca taaaagacag
    15901 gtttacgcat ggctgctcac ctccatgcgg cgggctaacc agcgttgcga aagacgaatt
    15961 aattcagctt tccgctggtg gtagtcctgg cctaactcaa tcagcgtgat attgctctgc
    16021 tcaaggtaag aaaggtgctc aagctgcagc gtgctcatgt ggtcgcgtgg ttcgcctgtg
    16081 atgccgttcg cctgcgccca ctgttttgca gtcatgccac ccagcacgat acgcgccagc
    16141 atattggctt ccgtggtgta gtggtgctgg agcgtgtttt tacccagttc agcgcggtac
    16201 gcctccagcg cggcacacat cggcttaaag tagctggcaa cggtgatacg ggctttcagt
    16261 tcacggcgta acgctgcgga acgcactggc gctactttgt gtagctcctc ctcgcatttg
    16321 atgaagtact gacgaacggc gcggccctgt tcggtgcgtt cgatcattgc cagttctttc
    16381 gccattccga cacttaacag atagtcttta ccgggtctgc cagagtgctt aatcttgctg
    16441 taagcctcgc cattcgggct tttccccaaa tttggggaaa ttgttttatg gactgagtaa
    16501 tcgtacccaa tggtgaagtc atattcagag atacgatcag tgatccatgt agagaagtct
    16561 tttcccacgc ccaacgcttt gtgtaacgct tttgcgctaa caacagcggc ttcacgcccg
    16621 ccaataacgc cggaaataac cgggataatt tcgccgaaat tttgcagatt ctggttttca
    16681 ggccgaacaa agccctgccc ctgtacgggc gtttttcgca gtttcataaa aactccgcta
    16741 tcgaattaag ttacttttta tttgctagtg gatagcttgg gcaataaccc gtagctattt
    16801 aatcaggcag ccgttccgcg tgattcggca atacgctgat tgatccattc gtcaatttca
    16861 ctttcaacga aagcaatcgc tcgcgagcca attttaactg atgcaggaaa tttaccttgc
    16921 cccataaggc gataaatcca tgccttgcta tatccagttc tacgctgaac ttctgttaaa
    16981 cgaataagcg tatttgacat ctatttacct cataacgtct actcaatttg acgaggtaat
    17041 catggcacag aaataacgaa tattttcata ccctcaggcc taatggttac cggaaggaaa
    17101 ttaaccctaa gggtgatggt aatcgggagg aaatctaccc taagggtgat ggtaaaattg
    17161 acggggaaga taaaaaaata ccctcagggt aacagtaaat caccctcagg gtatgcggta
    17221 tggtgcgtta atccggcttt gcgttctttt ggctgttgtc tcggttaata gggcaggcag
    17281 tcctctctat gagcgttgca agagcattac ttgcccccca ctgcttaagc tccctggtta
    17341 tcgcttcttg atttcccctg gtggcaaaat cattttctgg atcgtaattg gcccactctc
    17401 tgtttctaat ctcaatagcc ttagctaatg ggtctttatc ccagtattta tataagtgta
    17461 tcgggcgctc ttgctctaac tgctctatcc ttgcccttaa ctctgcgttt tctctttcca
    17521 gcattgcgat ttgggataat aaatcatcct ctgtacgcaa ctctttcttt tcaatatcgc
    17581 gtccttgtac ctcgtcattt tcagaagagt tagcgccttc cagcttcgtt aacgcgtcaa
    17641 ggacatcggg aaaaattgcg aaaatttcac cccttataaa tccaatgttc tcaaattcgg
    17701 gatcttccca ataaccggac accagaaaac cattttcatc cctctcacca ggtaaacaac
    17761 catgtttccg aaccgcatcc agatttctat aaagaacatc ataatcaaat tcatcccgat
    17821 acgggttaca aaaagattcc aacagcttaa attcatttac tgtgtacagg cggatatgtt
    17881 ctccgcttat tctcctgagt atccaagtta tgagatctga aacatcataa tcatcaccag
    17941 cgaccttaag cacgacctca agaaattcac gtaaagaaat aaaatctttt ttgtattcgt
    18001 ttaattcggc atgaatatca atcatacgca cacctcagcg tcctctactg tagtggctgt
    18061 gccagcccgt cgaggtatac ggtttttcgg gagcgaccct agacacagct ttttctttcg
    18121 tcgctcaaag tctactactg tatactcaac cagtcatcca cattttccga acttgccatg
    18181 caccacgttg ccgccctgtt ccagtgagtc catatagtcg gcgtaccact ggagcatctc
    18241 gcgccgcccg tccagatatt gcgcatgatt gtacgtgcca cgaattgagt tcttatcaac
    18301 gtgtgcaagc tgcgtttcta tccacgcggt gttatagccc tgctcatgta aaatcgtgct
    18361 catcgtgtgc cggaacccat gaccagtaac gcgcccagaa tagccaatac gacgaataag
    18421 cacgttcatc gccatttcac tcatcggctt actgtgctgg attcgaccag ggaaaataaa
    18481 ctgatactgc cccgtcatgt gttttaactg ttccagaata gcgatcgcct gttctgaaag
    18541 cggcacacaa tgaggacggc gcatcttcat tcgttcttta ggcacttccc acaaacgatt
    18601 atcaaaatcg atctcctgcc attctgcctg tcgtaattcc cctggccgga gccctgtcag
    18661 aatcaataat cgcataccca gcttgacgat ctggcttccg gtgtacgtat taagaacgcg
    18721 gaaaaattcc ggcagttcgt cggccttcaa ataggcataa tgctcttttt tgtgtggagc
    18781 aaatgcgctt gccagatctg gtgcggggtt atattcagcg cgtccggtga tgattgcgta
    18841 ccggaacacc tcgccgcatc gctggcgaac cttacgcaat ttttcggtcg ccccacggtc
    18901 attaagacgg gagagaaccg caagcaactc cattggctta atttctgcga tcggcctgcc
    18961 gccaatgtac ggaaaaacgt ctttttcaaa cgtctcgatc atttcctcgg cgtatgacga
    19021 tgaccacctg tcgatccgct tttcatacca ttcgcgagcg ataccctcaa aagtattgcc
    19081 aaatttgctc gcctgttctc gcttttgagc ttttctggcc tcacttggat ttataccacc
    19141 agcaagaagc cttttagcct catcccttgc cgctctggca tcagacagag acacatcagg
    19201 gtacacgccc aacgacaaca ttttgggctt tcctgcaaat ctgtaacgta gtcgccaccc
    19261 tttcgagccg ttcggctcaa tgagtaacga aagcccgtta ccgtcattga gtgtataagc
    19321 cttttctttc ggcttcgcgc gcctgatagc aaggtctgaa agcagcatgt gtatagctcc
    19381 aaaaaataaa ttttgtccta tacgcattac tatacacttc tgtgtgtaga ttctggtagt
    19441 tgtgagtaga cgttaataag ctatgaaaat ggctgaaagg cttgatattc gtggatttga
    19501 tggacttcag tagacgttga gaaatgtttg tttggagcgg gcgaagggaa tcgaaccctc
    19561 gtatagagct tgggaagctc tcgttctacc attgaactac gcccgcttcg agatgcgtaa
    19621 ggcattataa accttacgct ctccttagca agtaccgcgc tgctgactgc tgattaattc
    19681 gccatcagca ttttggcttg ctgccctgag gcggcaagta acgtagcgga tcaattgccg
    19741 ttgcacggta acgaatctgg aaatgcaggc gaaccgatgc cgcatcagtg ctccccatag
    19801 tggcgatttt ttgcccagcc ttcacgcttt gcccattatt taccagcatc gtgtcattat
    19861 gagcgtaagc cgtaatgtaa tcttcactgt gtttaatcat gatgagatta ccgtagccac
    19921 gcagctggtt gcccacatac accacctttc ctgcacccgc ggcgtaaata ggtgtacccc
    19981 gtggagctga gatatcaatc cctttattgc cgccatcagc tgtcgaatac ggcatgataa
    20041 ctttccctgt cgttggccat aaccaacaac gttgccctac tggcggccag gaagatttcg
    20101 gtactgctga tgacggtgta accgatgcgg ttttggtcgt tgatttggcg gttgatttac
    20161 gtgtactgct acttttcgcc ccacccagtt ttagtttctg accaacttca atggtgtaag
    20221 ggggggaaat gccgttcagt cgcgccagct cttttacgct ggttcccgtg gtgcgcgaaa
    20281 tacgatatag cgtatccccc cgtttcacgg tgtaaacgga gccggaatac gttcctgtat
    20341 cggatgattt gctacccgag cagcccgcca aaagcagtcc aaccgataac aacatcacga
    20401 tacccagaga ttttttattc aggcgtcccg cactcaaaat ctttcctcgc ttaaaaaaca
    20461 agacgccata tcatagcagc cagcctcttg atacccaatc tcttgcttct ggaaaaacgc
    20521 ggtaatagag aaagaggtta atttcatttg gcaaagggaa gtatcatcag caaaatattc
    20581 actgtagagg tatcgaattt cctgactcat ttaccctatt tcccatcctg atgcgtaata
    20641 atcccaattt atcacattga ttttatcgcc actcatattg atacgtatca ctgcccctat
    20701 tcagggtcct gtttcgtatc atatctgtgt ttttttaaca tcatcacact tccttcctcc
    20761 cttaacgctt atcgtcgttt ctggcgtaaa tcttgcctgc ttagactaaa tctttgccat
    20821 aagaaccaaa tgttcaaatc gaggggattt ctatggaagc gcgggaagca accgctacag
    20881 gtgaatcatg catgcgcgta gatgccattg ctaaggtcac cgggcgggca cgatatactg
    20941 acgattatgt tatggcgggc atgtgttacg cgaaatatgt acgtagccct atcgcacatg
    21001 gttatgccgt aagtattaat gatgaacaag ccagaagttt accgggcgta ctggcgattt
    21061 ttacctggga agatgtgcct gatatcccat tcgctacagc tgggcatgcc tggacacttg
    21121 acgaaaacaa gcgcgatacc gccgatcgcg cactgctaac tcgccatgtt cgtcaccatg
    21181 gtgacgccgt tgccatcgtc gtggcccgtg atgaactcac ggcagaaaaa gcggcgcaat
    21241 tggtcagcat tgagtggcaa gaattacccg ttatcaccac cccagaagcg gcgctggctg
    21301 atgacgctga accaatccat aacggcggca atttactaaa acaaagcacg atgtcgacgg
    21361 gcaatgtcca acaaacaatc gatgccgccg actaccaggt acaggggcac tatcagacgc
    21421 cggtcattca acattgtcac atggaaagcg tgacatcgct ggcatggatg gaggatgact
    21481 cgcgaattac catcgtttcc agcacccaga tcccacacat tgttcgccgt gtggttggtc
    21541 aggcgctgaa tattccctgg tcatgcgtac gagtcatcaa accgtttgtc ggtggcggtt
    21601 ttggtaataa acaggatgta ctggaagagc caatggcggc attcctgacc agcaagcttg
    21661 gcggcattcc ggtgaaagtt tcccttagcc gtgaagagtg tttcctcgca acccgtaccc
    21721 gccacgcttt tactattgac gggcaaatgg gcgtgaaccg cgacggaaca ttgaaaggtt
    21781 atagtctgga tgttctgtct aacaccggcg cttacgcatc tcacgggcac tccatcgctt
    21841 ctgcgggggg gaataaagtc gcttaccttt atcctcgttg tgcctacgct tacagttcaa
    21901 agacctgcta taccaacctc ccctcggctg gtgcgatgcg tggttatggc gcgccacaag
    21961 tcgtatttgc cgttgagtct atgcttgatg acgccgcgac agcgttaggt attgatcctg
    22021 ttgaaattcg tttacgcaac gccgcccgcg aaggagatgc taatccgctc acgggcaaac
    22081 gtatttacag cgcagggttg ccggagtgtc ttgaaaaagg ccggaaaatc tttgaatggg
    22141 aaaaacgccg tgcagagtgc cagaaccaga aaggcaattt acgccgcggc gttggcgtcg
    22201 cctgttttag ctacacctcg aacacctggc ctgtcggcgt agaaatagca ggcgcgcgcc
    22261 ttctgatgaa tcaggatgga accatcaacg tgcaaagcgg cgcgacggaa atcggtcagg
    22321 gtgccgacac cgtcttctcg caaatggtgg cagaaaccgt gggggttccg gtcagcgacg
    22381 ttcgcgttat ttcaacacaa gataccgatg ttacgccgtt cgatcccggc gcatttgcct
    22441 cacgccagag ctatgttgcc gcgcctgcgc tgcgcagtgc ggcactgtta ttaaaagaga
    22501 aaatcatcgc tcacgccgca gtcatgctac atcagtcagc gatgaatctg accctgataa
    22561 aaggccatat cgtgctgatt gaacgaccgg aagaaccgtt aatgtcgtta aaagatttgg
    22621 cgatggacgc tttctaccac cctgaacgcg gcgggcagct ctctgctgaa agctccatca
    22681 aaaccaccac taacccaccg gcgtttggct gtacctttgt tgatctgacg gtcgatattg
    22741 cgctgtgtaa agtcaccatc aaccgcatcc tcaacgttca tgattcgggg catattctaa
    22801 atccgctgct ggcagaaggt caggtacacg gcggaatggg aatgggcatt ggctgggcgc
    22861 tatttgaaga gatgatcatc gatgcgaaaa gcggcgtggt ccgtaacccc aatctgctgg
    22921 attacaaaat gccgaccatg ccggatctgc cacaactgga aagcgcgttc gtcgaaatca
    22981 atgagccgca atccgcatac ggacataagt cactgggtga gccaccaata attcctgttg
    23041 ccgctgctat tcgtaacgcg gtgaagatgg ctaccggtgt tgcaatcaat acactgccgc
    23101 tgacgccaaa acggttatat gaagagttcc atctggcagg attgatttga ggataacatc
    23161 atgtttgatt ttacttctta ccatcgcgca gcaacccttg ccgatgccat caacctgctg
    23221 gctgacaacc cgcaggccaa actgctcgcc ggtggcactg acgtactgat tcagctccac
    23281 catcacaatg accgttatcg ccatattgtt gatattcata atctggcgga gctgcgggga
    23341 attacgctgg cggaagatgg ctcactacgt atcggctctg caacgacatt tacccagctc
    23401 attgaagatc ctgtaactca acgtcatctc ccggcgttat gtgctgcggc ctcatccatt
    23461 gccggaccgc agatccgtaa cgtcgctacc tacggtggaa atatttgcaa cggtgctacc
    23521 agcgcagatt ctgccacgcc aacgctaatt tatgacgcga aactggagat tcactccccg
    23581 cgcggtgttc gtttcgtccc gattaatggc tttcacactg agccgggcaa agtgtctctt
    23641 gagcatgacg aaatccttgt cgcctttcat tttccgcccc agccgaaaga acacgcgggc
    23701 agcgcgcatt ttaaatatgc catgcgcgac gcaatggata tttcaacgat tggctgtgcc
    23761 gcacattgcc gactggataa cggcaatttc agcgaattac gcctggcatt tggtgttgcc
    23821 gcgccaacgc cgattcgctg ccaacatgcc gaacagactg cacaaaatgc gccattaaac
    23881 ctgcaaacgc tggaagctat cagcgaatct gtcctgcaag atgtcgcccc gcgttcttca
    23941 tggcgggcca gtaaagagtt tcgtctgcat ctcatccaga cgatgaccaa aaaagtgatt
    24001 agcgaagccg tcgccgcggc ggggggaaaa ttgcaatgaa tcacagcgaa acaattacca
    24061 tcgaatgcac cattaacggg atgccttttc agcttcacgc cgcaccaggc acgccgctct
    24121 cggaattact ccgcgaacaa ggactgctaa gtgtcaaaca agggtgctgc gtgggtgaat
    24181 gtggtgcctg tacggtgctg gtcgacggca cagcaataga cagttgctta taccttgccg
    24241 cctgggctga aggaaaagag atccgcacgc tggaaggtga agcgaaaggc ggaaaacttt
    24301 ctcatgttca gcaggcttat gcgaaatccg gcgcagtgca gtgcgggttt tgtacgccag
    24361 gcctgattat ggctaccacg gcaatgctgg cgaaaccacg cgagaagcca ttaaccatta
    24421 cggaaattcg tcgcggactg gcgggaaatc tttgtcgctg cacggggtat cagatgattg
    24481 taaatacagt tctggattgc gagaaaacga agtaaaagga tatccggcct gaattcaggc
    24541 cggattcact gaggttatgt gtttaacaac tcatatttct taatcttgcg atagagcgta
    24601 gcaatgccga tgcccagttc atcagcaact tccttcttgc tgttatgacg tgaaagcgcc
    24661 tcgcggatca tttgcttttc catctcctcc agcgccgtgc cgcccgcatc atcgagtgac
    24721 aggtgcgcct cactgacctc tgttacatca ctttgctccg ttgtgccatt attcagcaga
    24781 tttggtggca atagcgtgct gtcgataact tcacctgaag gaaccacgtt aaccagatat
    24841 tccatcaaat tgcttaactc gcgcaggttt ccgggccaac gatgcttacg caatatttcg
    24901 acgacatccg gagcaatgcc aggataaacc gatcccagac gacgggtatg cagatgtaaa
    24961 aagtaatgca ccagtaattc aatatcttcc tgacgttcac gcagcggtgg aagagttatc
    25021 gggataacat taagtcggta gaagagatct tcgcggaatt taccttcggc aatgaactgg
    25081 gccaaattct gattagttgc agaaatgatg cggatgtcga cttgtattgg gctactggca
    25141 ccaatcggca gaatttcacg cgcctcaata gcgcgcagta atttagcctg caacattaat
    25201 ggcatatcac caatttcatc gagaaacagc gtgcccgtat tcgccgcctg aatcaaccct
    25261 gttttaccgt tggcagaagc gccagtaaat gcgcctttaa cataaccgaa cagttcgctc
    25321 tccagaagct gttccggaat cgcggcacag ttgatagcaa taaagggttt attccgtctt
    25381 ccgctcaact tatggattgc acgggcgacg acttctttac ctgtgccgct ttcaccaacc
    25441 accataacgc tggatgggct gggtgcaata cggctaatga gtcgttttaa ttgccgcata
    25501 acacggcact cgccaaccaa ttgttcaata tgcggttcat caggtgcatt tgctacagaa
    25561 aaactggtat gcgattggtg aaacgccatt aaaaatagtt gtcggccctg gatgttatgc
    25621 aactgaccaa tgattaattc acttttatca tcccacgaaa caatatgttg catatgacca
    25681 tgggtaaaat tactctcaaa tgttaatggt ctgaaacgaa caggttttcc aataatatta
    25741 ttttgtacaa caccgagtgt ttttaaagct gtctgattaa caaattgaac acgattatca
    25801 gcatcaacca ctaacacgcc ctgatccata ttatcgatca tggtcgcgaa tattttactg
    25861 atgttatctc ctggtccctg atcctccaga agtttagaaa caaaaatggt ggatatatgg
    25921 cgaacgtaat cagaaaattc gcgtaaatta tcactaatat gctcttgttg ctcgtgggta
    25981 acggcaatca aacttatcac tccaacacaa cgatcctgta aaatgacagg cgtacccaga
    26041 aatgcttttt cgcggcaatt ttctttacta tcgcaacctt cacaaagggg atcgaagcga
    26101 gactgtgtca caactttttc agttttcgtt tccaggacgt ggcggagcag gcgtgagttg
    26161 ccgctcaact ggcgaccaag aaacttccca tacgcgcccg ttccggcgac gcgacacaag
    26221 ttttcatcaa cgatctcaac ctcaagctgc aaaacgctgg caagcattct ggcaaaacgc
    26281 tgaattgtcg gttgaatttg catcaatact gactgcgtag tagcaagctc catagcttta
    26341 ccttccagac ttacttaaaa gtcgatcatt gaagacgttg atggttcata gatcatgatg
    26401 atattaactc aggcgaaatt ggctttgata aaaacataag atttttatca ctttctaatg
    26461 aaattatgga agagatatca catttctata tcaatatgag aattacggcg gtgagtttat
    26521 caaactgaag agagatcgcc tgtcccttta tcttatttct gatacttagc agcaaataaa
    26581 taacgcgata aaaaaagcca aacgttttcg tattttacaa acaaccggaa gctggcatca
    26641 atttgtgatc aaccccacac attatccgtc aaattagtct tttgcagccc cgtggataat
    26701 tctggcacac ttattgttag tcccaggtat agctgtgaaa acaccaatca ctttggcaag
    26761 tcacagtgaa ataaaccact ttgcctgtca ttccactacc gggactttat gatgaaaact
    26821 gttaatgagc tgattaagga tatcaattcg ctgacctctc accttcacga gaaagatttt
    26881 ttgttaacgt gggaacagac gccagatgaa ctgaaacaag tactggacgt tgccgcagca
    26941 ttaaaagcac tgcgtgctga aaacatctca accaaagtct ttaatagtgg attaggtatt
    27001 tccgtattcc gcgacaactc cacccgtacc cgcttctctt atgcttccgc gcttaacctg
    27061 ctcggccttg cacagcaaga tctcgacgaa ggcaaatcac aaatcgctca cggcgaaacc
    27121 gtgcgtgaaa ccgccaatat gatctccttc tgcgccgacg ctattggtat tcgcgacgat
    27181 atgtatctgg gcgcaggcaa cgcctatatg cgtgaagttg gcgctgcact tgatgacggt
    27241 tacaagcagg gtgtgctgcc gcaacgtccg gctttagtga acctgcaatg cgatattgac
    27301 cacccgactc agtcaatggc tgacctggca tggttacgtg aacactttgg ttcactggaa
    27361 aacctgaaag gtaaaaaaat cgccatgacc tgggcctact ccccaagcta tggcaaaccg
    27421 ctctctgtac cacaaggcat catcggtctg atgactcgct tcggtatgga tgtcaccctg
    27481 gcccatccgg aaggctacga cctgatcccg gatgtcgttg aagtcgctaa aaacaatgct
    27541 aaagcctccg gcggtagctt ccgtcaggtc accagcatgg aagaagcctt caaagacgca
    27601 gacatcgttt atccgaagtc atgggcacct tacaaagtga tggaagagcg tactgaattg
    27661 ctgcgtgcga acgatcacga aggcttaaaa gcactggaaa aacagtgtct ggcacagaac
    27721 gcgcaacaca aagactggca ttgtactgaa gagatgatgg aactgacccg tgatggcgaa
    27781 gccctgtaca tgcactgcct gccagctgat atcagcggtg tatcctgcaa agaaggtgaa
    27841 gtgactgaag gcgtattcga aaaataccgt atcgctacct acaaagaagc cagctggaag
    27901 ccttatatca tcgccgcgat gatcctgtcc cgtaaatacg ccaaaccagg tgcactgctc
    27961 gagcaactgc tgaaagaagc gcaagaacgc gtgaaataac ccctcgggcc gatcagctgg
    28021 tcggccctct atttccagag gccaaaagga taggatatgt ccgttttctc attgaagatt
    28081 gatatcgccg ataacaaatt tttcaacggc gaaacatcac cgctcttttc gcaaagccag
    28141 gccaaactgg cgcgccagtt ccaccagaaa attgctggtt atcgcccaac accgctttgt
    28201 gcgctggacg atctcgcaaa cctttttggt gtgaagaaaa ttctcgtcaa agacgaatca
    28261 aaacgattcg gtctgaacgc cttcaaaatg ctcggcggtg cgtacgccat cgctcaatta
    28321 ttgtgtgaaa aatatcatct tgatatcgaa acgctgtcat ttgagcatct gaaaaatgcc
    28381 atcggcgaaa aaatgacctt cgcgaccacc accgacggca accacgggcg cggtgtggca
    28441 tgggcagcac agcaactcgg acagaatgcg gtgatttaca tgccgaaagg ttctgctcag
    28501 gaacgcgttg acgccattct gaacctcggt gccgagtgca tcgtcacgga tatgaactat
    28561 gacgataccg ttcgcctgac catgcaacac gcgcagcagc acggctggga agtggtacag
    28621 gatacagcat gggaaggtta caccaaaatc ccaacctgga tcatgcaagg ctacgcaacc
    28681 ctggcagatg aagccgtcga gcaaatgcgt gaaatgggcg taaccccgac gcacgttctg
    28741 ctgcaagccg gtgtcggtgc aatggccggt ggtgtgctgg gttatctggt cgacgtctat
    28801 agcccgcaaa atctgcacag cattattgtt gaacctgaca aagctgactg tatttatcgc
    28861 tccggcgtca aaggcgacat cgtcaacgtt ggcggtgata tggccaccat catggcgggc
    28921 ctggcctgtg gcgaacctaa cccgctgggc tgggaaatcc tacgtaactg cgccacccaa
    28981 ttcatctcct gccaggacag cgttgccgca ttaggtatgc gcgtgctggg taatccgtac
    29041 ggcaacgacc cgcgcatcat ctccggtgaa tccggcgctg tcggtttggg cgttctcgcg
    29101 gcggttcatt atcacccgca acgtcaaagc ctgatggaaa aactggcgct gaacaaagat
    29161 gccgtagtgc tggttatcag cactgaaggc gacacagacg tgaagcacta ccgcgaagtt
    29221 gtctgggaag gcaaacacgc tgtagcacct taatcaccct attggaactg ctccctgcaa
    29281 aacggggagt aaaaaatctg gagaaaaata atggctaaga atattccatt caaactgatt
    29341 cttgaaaaag caaaagatta ccaggcggac atgactcgct tcctgcgcga catggttgct
    29401 attcccagtg aaagctgcga cgaaaaacgc gtagtacatc gtattaaaga agagatggaa
    29461 aaagtcggct tcgataaagt tgaaatcgac ccgatgggca acgttctcgg ttatatcggc
    29521 cacggcccgc gtctggtggc aatggacgct catatcgata ccgtcggtat tggcaacatc
    29581 aaaaactggg acttcgatcc gtacgaaggc atggaaactg atgagctgat cggtggtcgc
    29641 ggtacttccg accaggaagg cggcatggca tctatggttt atgccggtaa aatcattaaa
    29701 gacctcggtc tggaagatga atataccctg ctggttaccg gtactgtgca ggaagaagac
    29761 tgcgacggcc tgtgctggca gtacattatt gaacaatccg gcattcgccc ggaatttgtg
    29821 gtcagtaccg aaccaaccga ctgccaggta taccgtggtc agcgcggtcg tatggaaatt
    29881 cgtattgatg ttcagggtgt tagctgccac ggttctgcac cagaacgcgg tgacaacgcc
    29941 attttcaaaa tgggtccgat tcttggcgaa ttacaagaac tctcccaacg tctgggttat
    30001 gacgaattcc tcggcaaagg caccctcacc gtttctgaaa tcttcttcac atccccaagc
    30061 cgttgcgctg tagcagatag ctgcgccgtc tctattgacc gccgtctgac ctggggcgaa
    30121 acctgggaag gcgcgctgga cgaaatccgc gccctgcctg cagtacagaa agctaacgcg
    30181 gttgtttcta tgtacaacta cgaccgtccg tcctggactg gcctggttta cccaaccgaa
    30241 tgctacttcc cgacctggaa agtggaagaa gatcacttca ccgttaaagc actggtgaat
    30301 gcctacgaag ggctgtttgg caaagcgccg gttgttgata agtggacctt ctcaactaac
    30361 ggcgtatcta tcatgggccg tcacggcatt ccggtgatcg gctttggccc gggtaaagaa
    30421 cctgaagcgc atgcacctaa cgaaaaaacc tggaaatctc acctggtgac ctgtgccgcg
    30481 atgtacgctg caatcccgtt aagctggctg gcaaccgaat aattactctt cacttattcc
    30541 cctccggttc gccggagggt ttttggagtt tgctatgcgc gtattgatca aaaacggcac
    30601 tgtcgttaac gcagatggac aagccaaaca ggatttgctg attgaaagcg ggattgttcg
    30661 ccagttgggc aacaatattt cgccgcagct cccgtatgaa gaaattgatg ccactggctg
    30721 ttacgttttc cctggcggcg tggatgtcca tacgcatttc aatattgatg tcggcatcgc
    30781 gcgcagttgt gatgattttt ttaccggtac ccgcgcagct gcgtgtggcg gtacaacaac
    30841 cattattgac catatgggat ttggcccgaa tggctgccgg ttacgccatc aactggaggt
    30901 ttatcgtggt tatgccgccc ataaggcggt catcgactac agctttcacg gtgtgatcca
    30961 gcacattaat cacgccatcc tcgacgaaat cccgatgatg gtcgaggaag ggctgagcag
    31021 ttttaaactc tatttaacct atcaatacaa actcaacgat gatgaagtgt tgcaggcatt
    31081 acgccgcttg catgaatccg gcgcgctgac caccgtgcac ccggaaaatg acgcagctat
    31141 cgccagcaag cgggcggagt ttatcgccgc agggttaacc gcgccgcgtt atcatgcctt
    31201 gagtcgacct ctggaatgcg aagcggaagc catcgcccgc atgattaacc tggcacaaat
    31261 tgccggtaac gccccgctct atatcgtgca cctgtctaac ggcttaggtc tggattatct
    31321 gcgtcttgcc cgtgcgaatc accagccagt ctgggttgaa acctgcccac aatatctcct
    31381 gttggacgaa cgcagttacg atacagaaga tggcatgaag ttcattctta gcccaccgct
    31441 gcgtaacgta cgcgagcagg acaaactgtg gtgtggcatc agcgatggtg cgattgacgt
    31501 ggtagcgacc gatcactgca cgttctcaat ggctcaacgc ctgcaaattt ctaaaggcga
    31561 tttcagtcgt tgcccaaatg gcttacccgg tgtggaaaac cgcatgcaac tgctgttctc
    31621 cagtggcgtg atgacgggac gtatctcacc ggagcgtttt gttgaattaa ccagcgcgat
    31681 gcccgccagg ctgtttggcc tgtggccgca aaaaggatta ttagcgcccg gttccgatgg
    31741 cgacgtggtg attatcgacc cacgccagag ccaacaaatt cagcatcgcc atctccacga
    31801 caacgctgac tattcgccat gggagggttt tacctgtcag ggcgcgattg tcagaacctt
    31861 atcccgtggt gaaacgattt tctgtgacgg cacctttaca ggcaaagccg ggcgaggtcg
    31921 tttcctgcga cgcaaaccgt ttgtccctcc cgtgctctaa ccactgccag ggatctatac
    31981 acaatcaaga atgatgagtg aggaaaaatg agtaagaaaa ttgttctcgc cctgggcggg
    32041 aatgcgctgg gcgatgacct ggccgggcaa atgaaagcgg taaaaattac ttctcaggca
    32101 attgttgatt taattgccca gggacatgaa gttatcgtca ctcatggtaa cgggccgcag
    32161 gtgggcatga ttaaccaggc ctttgaagct gccgcaaaaa ctgaagcgca ctcgccaatg
    32221 ctgccgatgt ctgtctgtgt tgcattaagc cagggttata ttggttacga tctacaaaac
    32281 gctttaagag aagaactgct ttctcggggc attaataaac ctgtagcaac gctggttact
    32341 caggtcgaag tcgacgctaa cgatccggca ttcctcaacc cgaccaagcc gatcggttcg
    32401 ttctttaccg agcaagaagc agagcaactg acaaaacagg gttacactct gaaagaagat
    32461 gctggtcgcg gctatcgtcg tgttgttgct tcaccaaaac cggttgatat tattgaaaaa
    32521 gagacggtaa aagcgctggt agaagcaggc caggtagtga tcaccgttgg cggtggtggc
    32581 attcccgtta ttcgtgaagg taaccatctg cgcggtgcca gtgcggttat cgataaagac
    32641 tgggccagcg cccgtttagc agaaatgatt gatgccgata tgctgatcat tctgactgcg
    32701 gtagaaaaag tggccattaa cttcggtaaa gagaatgaac agtggctcga tcgcctgtca
    32761 ttaagtgatg ctgaacgctt tatcgaagaa ggtcattttg cgaaaggttc tatgctgcct
    32821 aaagtggaag ctgccgcctc gtttgctcgc tctcgcgcag gtcgtgaagc actgattacc
    32881 gtattgagca aagcgaaaga agggattgaa ggcaaaaccg gaacggtgat ttgtcagtaa
    32941 tttaaaggcc ggatgggtaa taccatccgg ccattttcat ttaagccact tccagcactt
    33001 cttttgtcgc tttaacgccc tgatgcatca acatcattaa cgcctcaagt acgccgccgc
    33061 caatcgcccg ggctttatca gaaacgctgg tgaaatcagc cgtttcacca cgaggatcga
    33121 tatcaccaat tttaaaacca ccgaccactg ccagtccgtc gttcaacaag ccacgcacca
    33181 tccccgtcaa cggtgcttta atttcatgct caccaatcca ggcaatcaca tcgccctctt
    33241 tcaccagatc gcctaatttc acgttggatc gcataatgcc tgcagcagga gcacggatca
    33301 cccgtcgggt ggtatgcccc ataatattgc cgggaacacc ggtattctcc tgcgcacaac
    33361 cagagtaaat cacctgaccg agccagtgcc cgcgatttgt ttcaattacc gcatgacaat
    33421 ccttccctgc agtaaagccc ggcccaagcg cgattgttac tggtgccata tctgcccgcg
    33481 ttcccaaatt ctgtttcgcc agaatagcgt ccaccacgca aagcggtttc agttcatcaa
    33541 gcaatgaaca ggtgggatct accatcacag ggatgaatcc gcgttcggta agtttcatcg
    33601 cttccgcaga gctggttgcc aggcgggcgg tgacgccttc gaccgtcatt tcgccatcga
    33661 acacggcctg ggcaaacgcc acggtacaac gaatcactgt cggtttttcc acttccaaca
    33721 tgatcacttt aaaacccgca tgatacagac gtagcgctac accactggcg atatcccccg
    33781 caccgcgaat caccaccagc tggtgtccgg aaggatgaga aggcttcatc atcagcccac
    33841 ccggcgcgtt atttttcacc tgtaatattt ctgccagcac gctgatggcg atctcctgcg
    33901 gcgtttccgc acctatgttg taaccaacgg gcgcatgtaa acgggcaata tgttcttcag
    33961 ccacgccttt ctcacgcaat tgacgcagga aaagctgaac cttgcgacga cttgccagca
    34021 accccagcca tgcaatgggc tgttcaatga gtttgtcgag ggcttcacga tcctgattat
    34081 tcgtggcaat caggacaaaa ttatcagggc gaatatccag tgcttccact gccgcaccaa
    34141 acgactcagc atagagaagc gtggttgatg gtgggaatag ttcaggattg aggctttcgc
    34201 gataaatatc agcaacggca atatcaaatc ctaatagcgc cgcactctgg gctatcgccc
    34261 ggttgacatg ccccgcgcca atcaacacca gacgtggacg cataccatgg acgctgataa
    34321 atactgacat tgcacctcca caatctgacc cgacagcatc cgcaccgtta cgagccatac
    34381 gtccatggaa taatcgcggc ttacgttcct gcaatgcctg aagcgactct tcaatcacct
    34441 tccgctcaac cattccgcca ccaattgtac cgacgataga gccatcggcg cgcactaaca
    34501 tttgtgcaga atggcgggga gtcgagcctc ggctatcaac aatttgcgcc atcgcaaacg
    34561 gacaattttg ctcttcgagt tttgcagcct ctgtgaaaat attcatacca acctcaatgg
    34621 atatcctttc agtaacccgg aatacccggg ccgctaattc acaaatctgc gcgcgattgc
    34681 aggatgttct tgtatatcgc ccagccagat tgcctctacg ttgtgttgtt gcagcggttg
    34741 aaggagctcg ctttgcgcaa tcgcattctc acattgagaa aaacggttaa tgaaccagac
    34801 tcgccgacaa ccttgcggta cgtttttaaa cgccccctga gggtggcgaa ccagcgcaac
    34861 gagatcgctc agttgcaagg gtgcatcagg tgttaaccca gtaatatcag caaactgcga
    34921 ccagcgatgg acattttctg tgctcacttt cgcacccaaa atatgtcctc ccatcacagc
    34981 aatcacgcag caactgcttt taggtatgca aggttcgtgc tcatcaggcg cttttaacgg
    35041 cattccacgc gagccatctg cttcaatgag aattacgtca cactctggtc gttgtaccag
    35101 tgcatcaatc gcttctggcg taaatccctg cacttttccc tgattcgctt tccagctgtg
    35161 aaaacaaaat gaaatggggg atataaaaga cgcatgagga agcatggcgg gatcacgaca
    35221 gaaaaccacg ggccagtgag atgttggcat aaacatatgt gtcgtcgtag tgattaatac
    35281 acgcctgccg ctcgcctgga acagttctgc cagccaaaaa agcaagctgg ttttcccccc
    35341 agcaccaaca acagaaatca cagtgggacg tttctgcgcg cctaaatcaa tgaataatgc
    35401 cgatgggtca attatacttt tcacgcgtct ttatggacct ctctgggata aattatcccc
    35461 aacttaatcc atcaggaagt aacgcaatta tcaggcgtta ttagccccta taaataatgg
    35521 aaccactatg tcagccatcg actgtataat taccgctgcc ggattatcat caagaatggg
    35581 gcaatggaaa atgatgttac cctggcaaca gggaacaatt cttgatgcaa gtatcaaaaa
    35641 tgcgttgcag ttttgtagcc gaattatttt agtcaccggc tatcgtggta atgaactgca
    35701 cgaacgttat gcgaaccaga gtaatatcac tattatccac aacccagatt atgcgcaggg
    35761 tttactgaca tcagtaaagg ccgcagtacc cgcggtgcaa acagaacatt gttttctcac
    35821 ccacggtgac atgccaaccc tcaccatcga tatttttaga aaaatctggc cgttacgtaa
    35881 tgatggcgca atactgccac tccataatgg catccccggc catccgattt tagtgtcaaa
    35941 accatgcctg atgcaggcaa tccagcgacc caatgtcacc aatatgcgtc aggcactcct
    36001 tatgggagaa cattattccg tcgaaataga aaatgcagaa ataattttag atattgatac
    36061 tcctgacgac tttattacag cgaagaaaag gtatactgaa
//
LOCUS       DADXDL010000049        36078 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.049, whole genome shotgun sequence.
ACCESSION   DADXDL010000049 DADXDL010000000
VERSION     DADXDL010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 36078)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36078)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36078
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.049"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..255)
                     /locus_tag="IRB70_002683"
     CDS             complement(<1..255)
                     /locus_tag="IRB70_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632579.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDLALPAPLPFILSRTYSSYRTKT"
     gene            complement(415..627)
                     /gene="rpmE"
                     /locus_tag="IRB70_002684"
     CDS             complement(415..627)
                     /gene="rpmE"
                     /locus_tag="IRB70_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L31"
                     /protein_id="HBC0632580.1"
                     /translation="MKKDIHPKYEEITASCSCGNVMKIRSTVGHDLNLDVCSKCHPFF
                     TGKQRDVATGGRVDRFNKRFNIPGSK"
     gene            830..3028
                     /gene="priA"
                     /locus_tag="IRB70_002685"
     CDS             830..3028
                     /gene="priA"
                     /locus_tag="IRB70_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBC0632581.1"
                     /translation="MPVAHIALPVPLPRTFDYLLPEGMTVKAGCRVRVPFGKQQERIG
                     VVVSVSDVSELPLNELKAVVEVLDVEPVFTHSVWRLLLWAADYYHHPIGDVLFHALPI
                     LLRQGRPAANAPMWYWFATEQGQAVDLNSLKRSPKQQQALAALRQGKIWRDQVATLEF
                     NDAALQALRKKGLCDLASETPEFSDWRTNYAVSGERLRLNTEQATAVGAIHSAADTFS
                     AWLLAGVTGSGKTEVYLSVLENVLAQGKQALVMVPEIGLTPQTIARFRERFNAPVEVL
                     HSGLNDSERLSAWLKAKNGEAAIVIGTRSALFTPFKNLGVIVIDEEHDSSYKQQEGWR
                     YHARDLAVYRAHSEQIPIILGSATPALETLCNVQQKKYRLLRLTRRAGNARPAIQHVL
                     DLKGQKVQAGLAPALITRMRQHLQANNQVILFLNRRGFAPALLCHDCGWIAECPRCDH
                     YYTLHQAQQHLRCHHCDSQRPVPRQCPSCGSTHLVPVGLGTEQLEQTLAPLFPGVPIS
                     RIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSA
                     DFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTLLYKGYDAFAEQALAE
                     RRMMQLPPWTSHVIVRAEDHNNQHAPLFLQQLRNLILSSPLADDKLWVLGPVPALAPK
                     RGGRWRWQILLQHPSRVRLQHIINGTLALINTIPDSRKVKWVLDVDPIEG"
     gene            3184..4209
                     /gene="cytR"
                     /locus_tag="IRB70_002686"
     CDS             3184..4209
                     /gene="cytR"
                     /locus_tag="IRB70_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CytR"
                     /protein_id="HBC0632582.1"
                     /translation="MKAKKQETAATMKDVALKAKVSTATVSRALMNPDKVSQATRNRV
                     EKAAREVGYLPQPMGRNVKRNESRTILVIVPDICDPFFSEIIRGIEVTAANHGYLVLI
                     GDCAHQNQQEKTFIDLIITKQIDGMLLLGSRLPFDASIEEQRNLPPMVMANEFAPELE
                     LPTVHIDNLTAAFDAVNYLYEQGHKRIGCIAGPEEMPLCHYRLQGYVQALRRCGIMVD
                     PQYIARGDFTFEAGSKAMQQLLDLPQPPTAVFCHSDVMALGALSQAKRQGLKVPEDLS
                     IIGFDNIDLTQFCDPPLTTIAQPRYEIGREAMLLLLDQMQGQHVGSGSRLMDCELIIR
                     GSTRALP"
     gene            4301..5260
                     /gene="ftsN"
                     /locus_tag="IRB70_002687"
     CDS             4301..5260
                     /gene="ftsN"
                     /locus_tag="IRB70_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsN"
                     /protein_id="HBC0632583.1"
                     /translation="MAQRDYVRRSQPAPSRRKKSTSRKKQRNLPAVSPAMVAIAAAVL
                     VTFIGGLYFITHHKKEESETLQSQKVTGNGLPPKPEERWRYIKELESRQPGVRAPTEP
                     SAGGEVKTPEQLTPEQRQLLEQMQADMRQQPTQLVEVPWNEQTPEQRQQTLQRQRQAQ
                     QLAEQQRLAQQSRTTEQSWQQQTRTSQAAPVQAQPRQSKPASTQQPYQDLLQTPAHTT
                     AQSKPQQAAPVARAADAPKPTAEKKDERRWMVQCGSFRGAEQAETVRAQLAFEGFDSK
                     ITTNNGWNRVVIGPVKGKENADSTLNRLKMAGHTNCIRLAAGG"
     gene            5353..5883
                     /gene="hslV"
                     /locus_tag="IRB70_002688"
     CDS             5353..5883
                     /gene="hslV"
                     /locus_tag="IRB70_002688"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease subunit HslV"
                     /protein_id="HBC0632584.1"
                     /translation="MTTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVI
                     AGFAGGTADAFTLFELFERKLEMHQGHLVKAAVELAKDWRTDRMLRKLEALLAVADET
                     ASLIITGNGDVVQPENDLIAIGSGGPYAQAAARALLENTELSAREIAEKALDIAGDIC
                     IYTNHFHTIEELSYKA"
     gene            5893..7224
                     /gene="hslU"
                     /locus_tag="IRB70_002689"
     CDS             5893..7224
                     /gene="hslU"
                     /locus_tag="IRB70_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019841241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase ATPase subunit"
                     /protein_id="HBC0632585.1"
                     /translation="MSEMTPREIVSELDKHIIGQDNAKRSVAIALRNRWRRMQLNEEL
                     RHEVTPKNILMIGPTGVGKTEIARRLAKLANAPFIKVEATKFTEVGYVGKEVDSIIRD
                     LTDAAVKMVRVQAIEKNRYRAEELAEERILDVLIPPAKNNWGQTEQQQEPSAARQAFR
                     KKLREGQLDDKEIEIDLAAAPMGVEIMAPPGMEEMTSQLQSMFQNLGGQKQKARKLKI
                     KDAMKLLIEEEAAKLVNPEELKQDAIDAVEQHGIVFIDEIDKICKRGESSGPDVSREG
                     VQRDLLPLVEGCTVSTKHGMVKTDHILFIASGAFQIAKPSDLIPELQGRLPIRVELQA
                     LTTSDFERILTEPNASITVQYKALMATEGVNIEFTDSGIKRIAEAAWQVNESTENIGA
                     RRLHTVLERLMEEISYDASDLSGQTITIDADYVSKHLDALVADEDLSRFIL"
     gene            7291..8217
                     /gene="menA"
                     /locus_tag="IRB70_002690"
     CDS             7291..8217
                     /gene="menA"
                     /locus_tag="IRB70_002690"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBC0632586.1"
                     /translation="MTEQQISRTQAWLESLRPKTLPLAFAAIIVGTALAWWQGHFDPL
                     VALLALITAGLLQILSNLANDYGDAVKGSDKPDRIGPLRGMQKGVITQQEMKRALIIT
                     VVLICLSGLALVAVACHTLADFVGFLILGGLSIIAAITYTVGNRPYGYIGLGDISVLV
                     FFGWLSVMGSWYLQAHTLIPALILPATACGLLATAVLNINNLRDINSDRENGKNTLVV
                     RLGAVNARRYHACLLMGSLVCLALFNLFSLHSLWGWLFLLAAPLLVKQARYVMREMDP
                     VAMRPMLERTVKGALLTNLLFVLGIFLSQWAA"
     gene            8310..8795
                     /gene="rraA"
                     /locus_tag="IRB70_002691"
     CDS             8310..8795
                     /gene="rraA"
                     /locus_tag="IRB70_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001392924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E activity regulator RraA"
                     /protein_id="HBC0632587.1"
                     /translation="MKYDTSELCDIYQEDVNVVEPLFSNFGGRASFGGQIITVKCFED
                     NGLLYDLLEQNGRGRVLVVDGGGSVRRALVDAELARLAVQNEWEGLVIYGAVRQVDDL
                     EELDIGIQAMAAIPVGAAGEGIGESDVRVNFGGVTFFSGDHLYADNTGIILSEDPLDI
                     E"
     gene            complement(8880..9125)
                     /gene="zapB"
                     /locus_tag="IRB70_002692"
     CDS             complement(8880..9125)
                     /gene="zapB"
                     /locus_tag="IRB70_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septal ring assembly protein ZapB"
                     /protein_id="HBC0632588.1"
                     /translation="MTMSLEVFEKLEAKVQQAIDTITLLQMEIEELKEKNNSLSQEVQ
                     NAQHQREELERENNHLKEQQNGWQERLQALLGRMEEV"
     gene            9550..10395
                     /gene="glpF"
                     /locus_tag="IRB70_002693"
     CDS             9550..10395
                     /gene="glpF"
                     /locus_tag="IRB70_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol uptake facilitator protein GlpF"
                     /protein_id="HBC0632589.1"
                     /translation="MSQTSTLKGQCIAEFLGTGLLIFFGVGCVAALKVAGASFGQWEI
                     SVIWGLGVAMAIYLTAGVSGAHLNPAVTIALWLFACFDKRKVIPFIVSQVAGAFCAAA
                     LVYGLYYNLFFDFEQTHHIVRGSVESVDLAGTFSTYPNPHINFVQAFAVEMVITAILM
                     GLILALTDDGNGVPRGPLAPLLIGLLIAVIGASMGPLTGFAMNPARDFGPKVFAWLAG
                     WGNVAFTGGRDIPYFLVPLFGPIVGAIVGAFAYRKLIGRHLPCDICVVEEKETTTPSE
                     QKASL"
     gene            10418..11926
                     /gene="glpK"
                     /locus_tag="IRB70_002694"
     CDS             10418..11926
                     /gene="glpK"
                     /locus_tag="IRB70_002694"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBC0632590.1"
                     /translation="MTEKKYIVALDQGTTSSRAVVMDHDANIISVSQREFEQIYPKPG
                     WVEHDPMEIWATQSSTLVEVLAKADISSDQIAAIGITNQRETTIVWEKETGKPIYNAI
                     VWQCRRTAEICEHLKRDGLEDYIRSNTGLVIDPYFSGTKVKWILDHVEGSRERARRGE
                     LLFGTVDTWLIWKMTQGRVHVTDYTNASRTMLFNIHTLDWDDKMLEVLDIPREMLPEV
                     RRSSEVYGQTNIGGKGGTRIPISGIAGDQQAALFGQLCVKEGMAKNTYGTGCFMLMNT
                     GEKAVKSENGLLTTIACGPTGEVNYALEGAVFMAGASIQWLRDEMKLINDAYDSEYFA
                     TKVQNTNGVYVVPAFTGLGAPYWDPYARGAIFGLTRGVNANHIIRATLESIAYQTRDV
                     LEAMQADSGIRLHALRVDGGAVANNFLMQFQSDILGTRVERPEVREVTALGAAYLAGL
                     AVGFWQNLDELQEKAVIEREFRPGIETTERNYRYAGWKKAVKRAMAWEEHDE"
     gene            12061..13071
                     /gene="glpX"
                     /locus_tag="IRB70_002695"
     CDS             12061..13071
                     /gene="glpX"
                     /locus_tag="IRB70_002695"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HBC0632591.1"
                     /translation="MRRELAIEFSRVTESAALAGYKWLGRGDKNTADGAAVNAMRIML
                     NQVNIDGTIVIGEGEIDEAPMLYIGEKVGTGRGDAVDIAVDPIEGTRMTAMGQANALA
                     VLAVGDKGCFLNAPDMYMEKLIVGPGAKGTIDLNLPLADNLRNVAAALGKPLSELTVT
                     ILAKPRHDAVIAEMQQLGVRVFAIPDGDVAASILTCMPDSEVDVLYGIGGAPEGVVSA
                     AVIRALDGDMNGRLLARHDVKGDNEENRRIGEQELARCKAMGIEAGKVLRLGDMARSD
                     NVIFSATGITKGDLLEGISRKGNIATTETLLIRGKSRTIRRIQSIHYLDRKDPEMQVH
                     IL"
     gene            13168..13914
                     /gene="fpr"
                     /locus_tag="IRB70_002696"
     CDS             13168..13914
                     /gene="fpr"
                     /locus_tag="IRB70_002696"
                     /EC_number="1.18.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin--NADP(+) reductase"
                     /protein_id="HBC0632592.1"
                     /translation="MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEID
                     GERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDE
                     VPDCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK
                     RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESAVGLPMNKETSHVMLCGNPQMV
                     RDTQQLLKETRQMTKHLRRRPGHMTAEHYW"
     gene            complement(13919..14347)
                     /gene="uspD"
                     /locus_tag="IRB70_002697"
     CDS             complement(13919..14347)
                     /gene="uspD"
                     /locus_tag="IRB70_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspD"
                     /protein_id="HBC0632593.1"
                     /translation="MAYKHIGVAISGNEEDALLVNKALELARHNDAHLTLIHIDDGLS
                     ELYPGIYFPATEDILQLLKNKSDNKLYKLTKNIQWPKTKLRIERGEMPETLLEIMQKE
                     QCDLLVCGHHHSFINRLMPAYRGMINKLSADLLIVPFIDK"
     gene            complement(14374..14673)
                     /locus_tag="IRB70_002698"
     CDS             complement(14374..14673)
                     /locus_tag="IRB70_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF406 domain-containing protein"
                     /protein_id="HBC0632594.1"
                     /translation="MKDVVDKCSTKGCAIDIGTVIDNDNCTSKFSRFFATREEAESFM
                     TKLKELAAAASSADEGASVAYKIKDLEGQVELDAAFTFSCQAEMIIFELSLRSLA"
     gene            complement(14885..15325)
                     /locus_tag="IRB70_002699"
     CDS             complement(14885..15325)
                     /locus_tag="IRB70_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HBC0632595.1"
                     /translation="MTIQQWLFSFKGRIGRRDFWIWIGLWFAGMLVLFSLAGKNLLDI
                     QTAAFCLVCLLWPTAAVTVKRLHDRGRSGAWAFLMIVAWMLLAGNWAILPGVWQWAVG
                     RFVPTLILVMMLIDLGAFVGTQGENKYGKDTQDVKYKADNKSSN"
     gene            15426..16025
                     /locus_tag="IRB70_002700"
     CDS             15426..16025
                     /locus_tag="IRB70_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiiQ family protein"
                     /protein_id="HBC0632596.1"
                     /translation="MKPGCTLFFLLCSALTVTTTAHAQTPDTATTAPYLLAGAPTFDL
                     SISQFREDFNSQNPSLPLNEFRAIDSSPDKANLTRAASKINENLYASTALERGTLKIK
                     SIQMTWLPIQGPEQKAAKAKAQEYMAAVIRTLTPLMTKTQSQKKLQSLLTAGKNKRYY
                     TETEGALRYVVADNGEKGLTFAVEPIKLALSESLEGLNK"
     gene            16133..16900
                     /gene="tpiA"
                     /locus_tag="IRB70_002701"
     CDS             16133..16900
                     /gene="tpiA"
                     /locus_tag="IRB70_002701"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBC0632597.1"
                     /translation="MRHPLVMGNWKLNGSRHMVHELVSNLRKELAGVAGCAVAIAPPE
                     MYIDMAKREAEGSHIMLGAQNVDLNLSGAFTGETSAAMLKDIGAQYIIIGHSERRTYH
                     KESDELIAKKFAVLKEQGLTPVLCIGETEAENEAGKTEEVCARQIDAVLKTQGAAAFE
                     GAVIAYEPVWAIGTGKSATPAQAQAVHKFIRDHIAKVDANIAEQVIIQYGGSVNASNA
                     AELFAQPDIDGALVGGASLKADAFAVIVKAAEAAKQA"
     gene            complement(16955..17710)
                     /gene="cdh"
                     /locus_tag="IRB70_002702"
     CDS             complement(16955..17710)
                     /gene="cdh"
                     /locus_tag="IRB70_002702"
                     /EC_number="3.6.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol diphosphatase"
                     /protein_id="HBC0632598.1"
                     /translation="MKKAGLLFLVMIVIAVVAAGIGYWKLTGEESDTLRKIVLEECLP
                     NQQQNQNPSPCAEVKPNAGYVVLKDLNGPLQYLLMPTYRINGTESPLLTDPSTPNFFW
                     LAWQARDFMSKKYGQPVPDRAVSLAINSRTGRTQNHFHIHISCIRPDVREQLDNNLAN
                     ISSRWLPLPGGLRGHEYLARRVTESELVQRSPFMMLAEEVPEAREHMGSYGLAMVRQS
                     DNSFVLLATQRNLLTLNRASAEEIQDHQCEILR"
     gene            complement(17817..18806)
                     /gene="sbp"
                     /locus_tag="IRB70_002703"
     CDS             complement(17817..18806)
                     /gene="sbp"
                     /locus_tag="IRB70_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfate/thiosulfate ABC transporter
                     substrate-binding protein Sbp"
                     /protein_id="HBC0632599.1"
                     /translation="MNKWGVGLTFLLAATSVMAKDIQLLNVSYDPTRELYEQYNKAFS
                     AHWKQQTGDNVVIRQSHGGSGKQATSVINGIEADVVTLALAYDVDAIAERGRIDKEWI
                     KRLPDNSAPYTSTIVFLVRKGNPKQIHDWNDLIKPGVSVITPNPKSSGGARWNYLAAW
                     GYALHHNNNDQAKAQDFVRALYKNVEVLDSGARGSTNTFVERGIGDVLIAWENEALLA
                     ANELGKDKFEIVTPSESILAEPTVSVVDKVVEKKGTKEVAEAYLKYLYSPEGQEIAAK
                     NYYRPRDAEVAKKYENAFPKLKLFTIDEEFGGWTKAQKEHFANGGTFDQISKR"
     gene            complement(19126..20088)
                     /gene="pfkA"
                     /locus_tag="IRB70_002704"
     CDS             complement(19126..20088)
                     /gene="pfkA"
                     /locus_tag="IRB70_002704"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014072359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBC0632600.1"
                     /translation="MIKKIGVLTSGGDAPGMNAAIRGVVRSALTEGLEVMGIYDGYLG
                     LYEDRMVQLDRYSVSDMINRGGTFLGSARFPEFRDENIRAVAIENLKKRGIDALVVIG
                     GDGSYMGAMRLTEMGFPCIGLPGTIDNDIKGTDYTIGFFTALSTVVEAIDRLRDTSSS
                     HQRISVVEVMGRYCGDLTLAAAIAGGCEFVVVPEVEFSREDLVNEIKAGIAKGKKHAI
                     VAITEHMCDVDELAHFIEKETGRETRATVLGHIQRGGSPVPYDRILASRMGAYAIDLL
                     LAGYGGRCVGIQNEQLVHHDIIDAIENMKRPFKGDWLDCAKKLY"
     gene            complement(20269..21171)
                     /gene="fieF"
                     /locus_tag="IRB70_002705"
     CDS             complement(20269..21171)
                     /gene="fieF"
                     /locus_tag="IRB70_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709720.2"
                     /note="FieF, a metal efflux transporter, is a member of
                     the CDF (cation diffusion facilitator) family of
                     transporters; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDF family cation-efflux transporter FieF"
                     /protein_id="HBC0632601.1"
                     /translation="MNQSYGRLVSRAAIAATAMASLLLLIKIFAWWYTGSVSILAALV
                     DSLVDIGASLTNLLVVRYSLQPADDNHSFGHGKAESLAALAQSMFISGSALFLFLTGI
                     QHLVSPTPMTDPGVGVIVTIVALICTIILVSFQRWVVRRTQSQAVRADMLHYQSDVMM
                     NGAILLALGLSWYGWHRADALFALGIGIYILYSALRMGYEAVQSLLDRALPDEERQEI
                     IDIVTSWPGVSGAHDLRTRQSGPTRFIQIHLEMEDSLPLVQAHMVADQVEQAILRRFP
                     GSDVIIHQDPCSVVPREGKRSMLS"
     gene            complement(21320..21820)
                     /gene="cpxP"
                     /locus_tag="IRB70_002706"
     CDS             complement(21320..21820)
                     /gene="cpxP"
                     /locus_tag="IRB70_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell-envelope stress modulator CpxP"
                     /protein_id="HBC0632602.1"
                     /translation="MRIVTAAVMASTLAVSSLSHAAEVGSGDNWHPGEELTQRSTQSH
                     MFDGISLTEHQRQQMRDLMQQARHEQPPVNVSELETMHRLVTAENFDENAVRAQAEKM
                     ANEQIARQVEMAKVRNQMYRLLTPEQQAVLNEKHQQRMEQLRDVTQWQKSSSLKLLSS
                     SNSRSQ"
     gene            21970..22668
                     /gene="cpxR"
                     /locus_tag="IRB70_002707"
     CDS             21970..22668
                     /gene="cpxR"
                     /locus_tag="IRB70_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response regulator transcription
                     factor CpxR"
                     /protein_id="HBC0632603.1"
                     /translation="MNKILLVDDDRELTSLLKELLEMEGFNVIVAHDGEQALDLLDDS
                     IDLLLLDVMMPKKNGIDTLKALRQTHQTPVIMLTARGSELDRVLGLELGADDYLPKPF
                     NDRELVARIRAILRRSHWSEQQQNNDNGSPTLEVDALVLNPGRQEASFDGQTLELTGT
                     EFTLLYLLAQHLGQVVSREHLSQEVLGKRLTPFDRAIDMHISNLRRKLPDRKDGHPWF
                     KTLRGRGYLMVSAS"
     gene            22665..24038
                     /gene="cpxA"
                     /locus_tag="IRB70_002708"
     CDS             22665..24038
                     /gene="cpxA"
                     /locus_tag="IRB70_002708"
                     /EC_number="3.6.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress sensor histidine kinase CpxA"
                     /protein_id="HBC0632604.1"
                     /translation="MIGSLTARIFAIFWLTLALVLMLVLMLPKLDSRQMTELLDSEQR
                     QGLMIEQHVEAELANDPPNDLMWWRRLFRAIDKWAPPGQRLLLVTTEGRVIGAERSEM
                     QIIRNFIGQADNADHPQKKKYGRVELVGPFSVRDGEDNYQLYLIRPASSSQSDFINLL
                     FDRPLLLLIVTMLVSTPLLLWLAWSLAKPARKLKNAADEVAQGNLRQHPELEAGPQEF
                     LAAGASFNQMVTALERMMTSQQRLLSDISHELRTPLTRLQLGTALLRRRSGESKELER
                     IETEAQRLDSMINDLLVMSRNQQKNALVSETIKANQLWSEVLDNAAFEAEQMGKSLTV
                     NFPPGPWPLYGNPNAQESALENIVRNALRYSHTKIEVGFAVDKDGITITVDDDGPGVS
                     PEDREQIFRPFYRTDEARDRESGGTGLGLAIVETAIQQHRGWVKAEDSPLGGLRLVIW
                     LPLYKRS"
     gene            complement(24143..24817)
                     /gene="yiiM"
                     /locus_tag="IRB70_002709"
     CDS             complement(24143..24817)
                     /gene="yiiM"
                     /locus_tag="IRB70_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418346.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-N-hydroxylaminopurine resistance protein"
                     /protein_id="HBC0632605.1"
                     /translation="MRYPVDVYTGKIQAYPEGKPSAIAKIQVDGELMLTELGLEGDEQ
                     AEKMVHGGPDRALCHYPREHYLYWAREFPEQAELFVAPAFGENLSTDGLTESNVYMGD
                     IFRWGEALIQVSQPRSPCYKLNYHFDISDIAQLMQNTGKVGWLYSVIAPGLVSADAPL
                     ELVSRVSDVTVQEAAAIAWHMPFDDDQYHRLLSAAGLSKSWTRTMQKRRLSGKIEDFS
                     RRLWGK"
     gene            complement(24966..25949)
                     /gene="kdgT"
                     /locus_tag="IRB70_002710"
     CDS             complement(24966..25949)
                     /gene="kdgT"
                     /locus_tag="IRB70_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HBC0632606.1"
                     /translation="MQIKRSIEKIPGGMMLVPLFLGALCHTFSPGAGKYFGSFTNGMI
                     TGTVPILAVWFFCMGASIKLSATGTVLRKSGTLVVTKIAVAWVVAAIASRIIPEHGVE
                     VGFFAGLSTLALVAAMDMTNGGLYASIMQQYGTKEEAGAFVLMSLESGPLMTMIILGT
                     AGIASFEPHVFVGAVLPFLVGFALGNLDPELREFFSKAVQTLIPFFAFALGNTIDLTV
                     IAQTGLLGILLGVAVIIVTGIPLIIADKFIGGGDGTAGIAASSSAGAAVATPVLIAEM
                     VPAFKPMAPAATSLVATAVIVTSILVPILTSIWSRKVKARAAKIEILGTVK"
     gene            complement(26209..26829)
                     /gene="sodA"
                     /locus_tag="IRB70_002711"
     CDS             complement(26209..26829)
                     /gene="sodA"
                     /locus_tag="IRB70_002711"
                     /EC_number="1.15.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010345169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase [Mn]"
                     /protein_id="HBC0632607.1"
                     /translation="MSYTLPSLPYAYDALEPHFDKQTMEIHHTKHHQTYVNNANAALE
                     NLPEFANLPVEELITKLDQLPADKKTVLRNNAGGHANHSLFWKGLKKGTTLQGDLKAA
                     IERDFGSVDNFKAEFEKAAASRFGSGWAWLVLKGDKLAVVSTANQDSPLMGEAISGAS
                     GFPILGLDVWEHAYYLKFQNRRPDYIKEFWNVVNWDEAAARFAAKK"
     gene            27114..28147
                     /gene="rhaT"
                     /locus_tag="IRB70_002712"
                     /pseudo
     CDS             27114..28147
                     /gene="rhaT"
                     /locus_tag="IRB70_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418343.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose/proton symporter RhaT"
     gene            complement(28144..29010)
                     /gene="rhaR"
                     /locus_tag="IRB70_002713"
     CDS             complement(28144..29010)
                     /gene="rhaR"
                     /locus_tag="IRB70_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418342.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaR"
                     /protein_id="HBC0632608.1"
                     /translation="MAEVATVAHQLKLLKDDFFASDQQAVAVADRYPQDVFAEHTHDF
                     CELVIVWRGNGLHVLNDRPYRITRGDLFYIHADDKHSYASVNDLVLQNIIYCPERLKL
                     NLDWQGAIPGFSASAGQPHWRLGSVGMAQARQVIGQLEHESSQHVPFANEMAELLFGQ
                     LVMLLNRHRYTSDSLPPTSSETLLDKLITRLAASLKSPFALDKFCDEASCSERVLRQQ
                     FRQQTGMTINQYLRQVRVCHAQYLLQHSRLLISDISTECGFEDSNYFSVVFTRETGMT
                     PSQWRHLNSQKD"
     gene            complement(29066..29902)
                     /gene="rhaS"
                     /locus_tag="IRB70_002714"
     CDS             complement(29066..29902)
                     /gene="rhaS"
                     /locus_tag="IRB70_002714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator RhaS"
                     /protein_id="HBC0632609.1"
                     /translation="MTVLHSVDFFPSGNASVAIEPRLPQADFPEHHHDFHEIVIVEHG
                     TGIHVFNGQPYTITGGTVCFVRDHDRHLYEHTDNLCLTNVLYRSPDRFQFLAGLNQLL
                     PQEQDGQYPSHWRVNHSVLQQVRQLVAQMEQQEGENDLPSTASREILFMQLLLLLRKS
                     SLQENLENSASRLNLLLAWLEDHFADEVNWDAVADQFSLSLRTLHRQLKQKTGLTPQR
                     YLNRLRLMKARHLLRHSEASVTDIAYRCGFSDSNHFSTLFRREFNWSPRDIRQGRDGF
                     LQ"
     gene            30190..31659
                     /gene="rhaB"
                     /locus_tag="IRB70_002715"
     CDS             30190..31659
                     /gene="rhaB"
                     /locus_tag="IRB70_002715"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBC0632610.1"
                     /translation="MTFRNCVAVDLGASSGRVMLARYERECRSLTLREIHRFNNGLHS
                     QNGYVTWDVDSLESAIRLGLNKVCEEGIRIDSIGIDTWGVDFVLLDLQGKRVGLPVAY
                     RDSRTHGLMTQAQQQLGKRDIYQRSGIQFLPFNTLYQLRALTEQQPELIPHIAHALLM
                     PDYFSYRLTGKMNWEYTNATTTQLVNINSDDWDESLLAWSGANKAWFGHPTHPGNVIG
                     HWICPQGNEIPVVAVASHDTASAVIASPLNGSRAAYLSSGTWSLMGFESQTPFTNDTA
                     LAANITNEGGAEGRYRVLKNIMGLWLLQRVLQERQINDLPALIAATQALPACRFIINP
                     NDDRFINPDEMCSEIQAACRETAQPIPESNAELARCIFDSLALLYADVLHELAQLRGE
                     DFSQLHIVGGGCQNTLLNQLCADACGIRVIAGPVEASTLGNIGIQLMTLDELNNVDDF
                     RQVVSTTANLTTFTPNPDSEIAHYVARIHSTRQTKELCA"
     gene            31656..32915
                     /gene="rhaA"
                     /locus_tag="IRB70_002716"
     CDS             31656..32915
                     /gene="rhaA"
                     /locus_tag="IRB70_002716"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBC0632611.1"
                     /translation="MTTQLEQAWELAKQRFAAVGIDVEEALRQLDRLPVSMHCWQGDD
                     VSGFENPEGSLTGGIQATGNYPGKARNASELRADLEQAMRLIPGPKRLNLHAIYLESD
                     TPVSRDQIKPEHFKNWVEWAKANQLGLDFNPSCFSHPLSADGFTLSHADDSIRQFWID
                     HCKASRRVSAYFGEQLGTPSVMNIWIPDGMKDITVDRLAPRQRLLAALDEVISEKLDP
                     AHHIDAVESKLFGIGAESYTVGSNEFYMGYATSRQTALCLDAGHFHPTEVISDKISAA
                     MLYVPQLLLHVSRPVRWDSDHVVLLDDETQAIASEIVRHDLFDRVHIGLDFFDASINR
                     IAAWVIGTRNMKKALLRALLEPTAELRKLEAAGDYTARLALLEEQKSLPWQAVWEMYC
                     QRHDTPAGSEWLENVRTYEKEILSRRG"
     gene            33192..34016
                     /gene="rhaD"
                     /locus_tag="IRB70_002717"
     CDS             33192..34016
                     /gene="rhaD"
                     /locus_tag="IRB70_002717"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBC0632612.1"
                     /translation="MQNITQSWFVQGMIKATTDAWLKGWDERNGGNLTLRLDDADIAP
                     YHGNFHAQPRYIPLIQPMPLLANTPFIVTGSGKFFRNVQLDPAANLGVVKVDSDGAGY
                     HILWGLTNEAVPTSELPAHFLSHCERIKATNGKDRVIMHCHATNLIALTYVLENDTAL
                     FTRQLWEGSTECLVVFPDGVGILPWMVPGTDEIGQATAQEMQKHSLVLWPFHGVFGSG
                     PTLDETFGLIDTAEKSAQVLVKVYSMGGMKQTISREELIALGQRFGVTPLASALAL"
     gene            34026..34340
                     /gene="rhaM"
                     /locus_tag="IRB70_002718"
     CDS             34026..34340
                     /gene="rhaM"
                     /locus_tag="IRB70_002718"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBC0632613.1"
                     /translation="MIRKAFVMQVNPDAHEEYQRRHNPIWPELEAVLKSHGAHNYAIY
                     LDKARNLLFATVEIESEERWNAVASTDVCQRWWKYMTDVMPANPDNSPVSSELQEVFY
                     LP"
     gene            complement(34381..35775)
                     /locus_tag="IRB70_002719"
     CDS             complement(34381..35775)
                     /locus_tag="IRB70_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate porin"
                     /protein_id="HBC0632614.1"
                     /translation="MKKSTLSLAIGLLLACSTGMAKTQHLTLEQRMALLEERLEAAEM
                     RAAKAESQVKQLQTQQAAEIREIKAAQGNTPVNGQATAESAKKNSTSPNLLLSGYGDL
                     KIYGDVEFNMDAESNHGLLAMTNADVNSDPTNEQWNLNGRILLGFDGMRKLDNGYFAG
                     FSAQPLGDMHGSVNIDDAVFFFGKENDWKVKVGRFEAYDMFPLNQDTFVEHSGNTAND
                     LYDDGSGYIYMMKEGRGRSNAGGNFLVSKQLDNWYFELNTLLEDGTSLYNDGNYHGRD
                     MEQQKNVAYLRPVIAWSPTEEFTVSAAMEANVVNNAYGYTDSKGNFVDQSDRTGYGMS
                     MTWNGLKTDPENGVVVNLNTAYLDANNEKDFTAGINALWKRFELGYIYAHNKIDEFSG
                     VVCDNDCWIDDEGTYTIHTIHASYQFANVMDMENFNIYLGTYYSILDSDGDKKHGDDT
                     DDRYGARVRFKYFF"
BASE COUNT         8870 a         9339 c         9265 g         8604 t
ORIGIN      
        1 cgtttttgtc cggtaactgc tgtaggtgcg ggagaggatg aacggcagcg gggcgggcag
       61 ggcaaggtcg gtttcgccgg gaaggacctt tgcacccagc agcggattga ccggatgacc
      121 ggacgtcacc ccgccggggc acactgaaca ggccacgccg gtgggggcac caatacgcac
      181 cccggcagaa ccctgaacaa tgctaccgcc atactgcgtc atgtcgccct gacgcgccgc
      241 cggttttccg ctcatcgtaa aatcctttta aaataaataa gaaccagaag cctagcgcca
      301 gtcaacaaca ggaaatgata atgagttaac accccggaat ttttcagaat ttataaaagg
      361 caaattacag gcacaaaaaa agcgccgtgc ggcgcttttt tcggaaatcc ggtcttattt
      421 gctgcccggg atgttgaaac gcttgttgaa gcggtcaaca cggccaccgg tagcaacatc
      481 acgctgtttg ccagtgaaga acgggtggca cttgctgcac acgtcgaggt tcaggtcatg
      541 accaacggtg gagcggattt tcattacgtt accgcaagag cagctagcag taatttcttc
      601 gtatttcggg tgaatatctt ttttcatggg aaaacctcgg tttaaggccg cgtcgctctt
      661 ccagccctaa cgccagacac cacgcgatgt taaaagtata gcttcaatac gatcatttcg
      721 tacgaaggcg cgaaatcata cagaaattaa ccagcggatg caaactgatc cgcactcttc
      781 tacggcaatg tgtatactaa cccaccgaat ttcaagtcag gatgatgcta tgcccgttgc
      841 ccacattgcc ttgcccgttc cgcttcctcg tacctttgac tatctgctgc cagaaggcat
      901 gacggttaaa gccgggtgtc gcgtgcgcgt gccatttggc aaacagcagg agcgcatcgg
      961 ggttgtggtg tcagttagcg atgtcagtga gctgccgctt aacgagctga aagcggtagt
     1021 tgaagtgctg gacgttgagc cggtatttac tcactccgtc tggcgattac tgctctgggc
     1081 ggcagattac tatcatcatc cgattggcga tgtgctgttt catgccttgc cgattttact
     1141 acgccagggg cggcctgcgg cgaacgcgcc gatgtggtac tggtttgcca ctgaacaagg
     1201 tcaggcggtg gatcttaaca gcctgaaacg ctcacccaag caacaacagg cactggcagc
     1261 gttacggcaa ggcaaaatct ggcgtgatca ggttgccacg ctcgaattta atgatgccgc
     1321 gttgcaggcg ctgcgcaaaa aaggtctgtg tgatttagca agtgaaacac cagagtttag
     1381 cgactggcgc acgaactatg ccgtttctgg tgaacggttg cgattgaata ccgaacaggc
     1441 caccgccgtt ggcgcaattc atagcgcggc ggataccttc tctgcctggc tgctggcggg
     1501 cgttacaggt tccggtaaaa cagaggttta tttgagcgta ctggaaaacg tgctcgctca
     1561 gggcaaacag gcgctggtga tggtgccgga aatcggcctg acaccgcaaa ctatcgcccg
     1621 ttttcgtgaa cgttttaatg cccccgtgga agttctgcat tccggcctga acgacagcga
     1681 gcgtctttcg gcgtggctga aagcgaaaaa tggtgaggcg gcgattgtga tcggcacccg
     1741 ctccgcgctg tttacgccgt ttaaaaatct cggcgtgatt gtcattgatg aagagcacga
     1801 tagctcctac aagcagcagg aaggctggcg ctatcatgcc cgcgacctgg cggtgtatcg
     1861 tgcgcacagc gagcaaatcc cgattattct tggctccgca acgcccgcgc tggaaacatt
     1921 atgcaacgtc cagcagaaaa aataccgcct gctgcgcctg acccgtcggg cgggcaatgc
     1981 gcgcccggca attcaacatg tgctggattt aaaaggtcag aaggtgcagg caggtctggc
     2041 tccggcgtta atcacccgta tgcgccagca tttacaggcc aacaatcagg ttatcctctt
     2101 tcttaaccgc cggggttttg cgcctgcgct actgtgccac gactgtggct ggatagccga
     2161 atgcccacgt tgcgatcact actacacgct gcatcaggcg caacagcatt tgcgttgcca
     2221 ccactgtgac agtcagcgtc cggtgccgcg ccagtgccct tcttgcggtt ccacgcacct
     2281 ggtccccgtg gggctgggca ccgaacagct tgaacagacg ctcgcaccgt tgttccctgg
     2341 tgtgcccatt tctcgtatcg accgcgatac caccagccgt aaaggtgcgc tggaacaaca
     2401 actggcggaa gtacatcgcg gtggcgcgag gattttgatc ggcacgcaaa tgctggcgaa
     2461 aggtcaccac tttccggatg tgacgctggt ggcgttactg gacgtagacg gcgcgctgtt
     2521 ttctgccgat tttcgctcgg cagagcgttt cgcccagctt tacacccagg tcgccggtcg
     2581 tgccgggcgt gcgggtaaac agggcgaagt ggtgctgcaa acgcaccatc ctgaacatcc
     2641 gctgttgcaa acgttgctct ataaaggcta cgacgccttt gccgaacagg cactggctga
     2701 acgacgcatg atgcagctgc cgccgtggac cagccatgtg attgtgcgtg cggaagatca
     2761 taacaatcag cacgcgccgc tgttcctgca acaactgcgt aatctcatcc tctccagccc
     2821 gctggcagac gacaaactgt gggttctcgg tccggttccg gcgctggctc cgaaacgtgg
     2881 tggtcgctgg cgctggcaaa ttttgttgca gcacccttcc cgcgtgcgct tacagcacat
     2941 catcaatggt acgctggcac ttattaatac aataccggat tcccgcaagg tgaaatgggt
     3001 actggatgtt gatccgattg agggttaaac cgctcacgat gcgaggcgga tcgaaaaatt
     3061 caatattcat cacacttttc atgaaaattc tgtaaccgtt ttcacgcgct atctgctaaa
     3121 aatgttgccg atgtgaagta aacatggatg tagtacgcct gacgtgccag gcgaggagtg
     3181 agtgtgaaag cgaagaagca ggaaactgcc gcgaccatga aagacgttgc cctcaaggca
     3241 aaagtctcta cagcgactgt ctcccgagca ttaatgaatc ccgataaagt ctcccaggcc
     3301 acccgtaatc gggttgaaaa agcggcccgg gaagtgggtt atttaccgca gcctatgggg
     3361 cgcaacgtca agcgtaatga atcccgcacc attctggtga ttgtcccgga tatctgcgac
     3421 cctttcttta gcgaaattat tcgcggtatc gaagttacgg cggcaaatca cggatatctg
     3481 gtgctgattg gcgactgtgc gcatcaaaat cagcaggaaa aaacctttat cgatttgatc
     3541 atcaccaagc aaattgatgg catgttgctg ctgggttcaa ggctgccgtt tgatgccagc
     3601 attgaggaac agcgtaatct gccgccgatg gtgatggcga acgaatttgc accggaactg
     3661 gagctaccta ccgttcatat agacaatctg accgccgcat ttgatgcagt aaattattta
     3721 tatgagcaag ggcataaacg gattggctgt atagccggtc ccgaagagat gccgctgtgt
     3781 cactaccgcc tgcaaggtta cgttcaggcg ctgcgtcgct gcggcattat ggttgatccg
     3841 caatacatcg cccgtggcga cttcaccttc gaagccggaa gcaaagcaat gcaacagctg
     3901 cttgatcttc cacaaccgcc tactgctgtc ttctgccata gtgatgtgat ggcgctcggc
     3961 gcactttctc aggcaaaacg ccaggggctg aaagtcccgg aagacctttc cataatcggt
     4021 tttgataaca tcgacctgac gcaattttgt gatccgccgc tgacaaccat cgcgcagccg
     4081 cgttacgaaa tcggtcggga agctatgctg ttattgcttg atcaaatgca ggggcaacac
     4141 gttggcagtg gctctcgttt aatggactgc gaacttatca tccggggatc aacacgcgcg
     4201 ttaccttaaa gtaaaccttt aagactgccg tgactggtca aaggcccgcc gcttaagtaa
     4261 catggcgggc tgacgaacga ataaatacag cgaaacgata gtggcacaac gagattatgt
     4321 acgccgcagc caaccggcac cttcgcggcg aaaaaagagc acctcacgga aaaagcaacg
     4381 aaatctgcct gcggtttctc ccgctatggt cgctattgct gccgccgttc ttgtgacctt
     4441 tatcggtggt ctgtacttca ttacgcatca caagaaagaa gagtccgaga cgctgcaaag
     4501 ccagaaagtg accggaaacg gactaccacc gaaaccagaa gaacgctggc gctacatcaa
     4561 agagctggaa agtcgccagc cgggtgtgcg tgcgcccaca gaaccttctg ccgggggtga
     4621 agtgaaaacg ccggagcaac taacaccaga acaacgccag cttcttgagc aaatgcaggc
     4681 cgatatgcgc cagcagccaa cgcagctggt tgaagttccg tggaatgagc agacaccgga
     4741 acagcgtcag caaacgctac agcgccagcg tcaggcgcag caattagcgg agcagcaacg
     4801 cctggctcag cagtcgcgta caactgaaca aagctggcag cagcagacgc gtacgtcgca
     4861 agccgcaccg gtacaggcgc aaccgcgcca gtctaaaccg gcttctactc agcagccgta
     4921 ccaggatctg ctgcaaaccc ctgcgcacac caccgcgcag tcgaagccgc agcaagctgc
     4981 gccagttgct cgtgccgctg acgcgccaaa accgacggcg gagaaaaaag acgaacgccg
     5041 ctggatggtg cagtgcggtt cgttcagagg cgcggaacag gcagagacgg tacgtgctca
     5101 gctggcgttt gaaggctttg actcaaaaat taccaccaac aatggctgga atcgtgtggt
     5161 cattggcccg gtgaaaggca aagagaacgc agacagcacc ctcaatcgct tgaagatggc
     5221 gggtcataca aactgcattc ggctcgccgc cgggggttga aaccctcaaa atccccccca
     5281 tctataattg cattatgccc cgtacttttg tacggggttt gttctctgta ttcgtaacca
     5341 aggggtcagc tcgtgacaac tatagtaagc gtacgccgta acggccatgt ggtcatcgct
     5401 ggtgatggtc aggccacgtt gggcaatacc gtaatgaaag gcaacgtgaa aaaggtccgc
     5461 cgtctgtaca acgacaaagt catcgcgggc tttgcgggcg gtactgcgga tgcttttacg
     5521 ctgttcgaac tgtttgaacg caaactggaa atgcatcagg gccatctggt caaagccgcc
     5581 gttgagctgg caaaagactg gcgtaccgat cgcatgctgc gcaaacttga agcactgctg
     5641 gcagtcgcgg atgaaaccgc ttcgcttatc atcaccggta acggtgacgt ggtgcagcca
     5701 gaaaacgatc ttattgctat cggctccggc ggcccttacg cccaggctgc ggcgcgcgcg
     5761 ctgttagaaa acactgaact tagcgcccgt gaaattgctg aaaaggcgtt ggatattgca
     5821 ggcgacattt gcatctatac caaccatttc cacaccatcg aagaattaag ctacaaagcg
     5881 taaggatctc ccatgtctga aatgacccca cgcgaaatcg tcagcgaact ggataaacac
     5941 atcatcggtc aggacaacgc caagcgttcc gtggcgattg ctctgcgtaa ccgctggcgt
     6001 cgcatgcagc tcaacgaaga gctgcgccat gaagtgaccc cgaaaaatat cctgatgatc
     6061 ggcccgaccg gtgtcggtaa aactgaaatc gcccgtcgtc tggctaagct ggcgaatgcg
     6121 ccgttcatca aagttgaagc aaccaaattc accgaagtgg gctatgtcgg taaggaagtg
     6181 gattctatta ttcgcgatct gaccgatgcc gccgtgaaaa tggtacgcgt ccaggctatc
     6241 gagaaaaacc gttatcgcgc tgaagaactg gcagaagaac gtattctcga cgtactgatc
     6301 ccaccggcta aaaacaactg gggacagacc gaacagcagc aggaaccgtc cgctgctcgt
     6361 caggcattcc gcaaaaaact gcgtgaaggc cagcttgatg acaaagaaat cgagatcgat
     6421 cttgccgcag caccgatggg cgttgaaatt atggctcctc cgggcatgga agagatgacc
     6481 agccagctgc agtccatgtt ccagaacctg ggcggtcaga agcaaaaagc gcgtaagctg
     6541 aaaatcaaag acgccatgaa gctgctgatt gaagaagaag cggcgaaact ggtgaacccg
     6601 gaagagctga agcaagatgc tatcgacgct gttgagcagc acgggatcgt gtttatcgac
     6661 gaaatcgaca aaatctgtaa gcgcggcgag tcttccggtc cggatgtttc tcgtgaaggc
     6721 gttcagcgtg acctgctgcc gctggtagaa ggttgcactg tttccaccaa acacgggatg
     6781 gtcaaaactg accacattct gtttatcgct tctggcgcgt tccagattgc gaaaccgtct
     6841 gacctgatcc cggaactgca aggtcgcctg ccaatccgcg ttgagctgca ggcactgacc
     6901 accagcgact ttgagcgtat tctgaccgag ccgaatgcct ctatcaccgt gcagtacaaa
     6961 gcactgatgg caactgaggg cgtaaatatc gagtttaccg actccggtat taagcgcatc
     7021 gcggaagcgg catggcaggt gaacgaatct accgaaaaca tcggtgctcg tcgtttacat
     7081 accgttctgg agcgtttaat ggaagagatt tcctacgacg ccagcgattt aagcggtcaa
     7141 actatcacta ttgacgcaga ttatgtgagc aaacatctgg atgcgttggt ggcagatgaa
     7201 gatctgagcc gttttatcct ataatcgcgt tcaatcattt tcatcattgt ttgatggggc
     7261 tgaaaggccc catttttatt ggcgcgtatt atgactgaac aacaaattag ccgaactcag
     7321 gcgtggctgg aaagtttacg acctaaaacc ctccccctcg cctttgctgc aattatcgtc
     7381 gggacggcgc tggcatggtg gcaaggtcac ttcgatccac tggtcgccct gctggcattg
     7441 attaccgccg ggctattaca gatcctttct aacctcgcca atgattacgg cgatgcggta
     7501 aaaggcagcg ataaacctga ccgcattggg ccgctacgcg gcatgcaaaa aggggtcatt
     7561 acccagcaag agatgaaacg ggcgctcatt attaccgtcg tgctcatctg tctctccggg
     7621 ctggcactgg ttgcagtggc gtgccatacg ctggccgatt ttgtcggttt cctgattctt
     7681 ggcgggttgt cgatcattgc cgctatcacc tacaccgtgg gcaatcgtcc ttatggttat
     7741 atcggtttgg gtgatatttc cgtactggtt ttctttggct ggttgagcgt catggggagc
     7801 tggtatttac aggctcatac attgattccg gcactgatcc ttccggcaac cgcatgcggc
     7861 ctgctggcaa cggcagtact gaacattaat aacctgcgtg atatcaatag cgaccgcgaa
     7921 aacggcaaaa acacgctggt ggtgcgctta ggtgcagtaa acgcgcgtcg ttatcatgcc
     7981 tgcctgctga tgggctctct ggtgtgtctg gcgctgttta atctcttttc gctgcatagc
     8041 ctgtggggct ggctgttcct gctggcggca ccgttgctgg tgaagcaagc tcgttatgtg
     8101 atgcgcgaaa tggacccggt ggcgatgcga ccaatgctgg aacgcactgt caaaggagcg
     8161 ttactgacta acctgctgtt tgttttaggg atattcctaa gccagtgggc agcataactg
     8221 acaaatatca attaacaatt gatgattttg ccaacagcct acatagcgcg atatactgaa
     8281 aattctcgca gcaactgaat gttaagccta tgaaatacga tacttccgag ctttgtgaca
     8341 tctatcaaga agatgttaac gtcgtggaac cgctgttctc caactttggc ggacgggcgt
     8401 cgtttggcgg acaaataatc acggtaaaat gtttcgagga caacgggttg ctgtacgatc
     8461 tgctcgaaca gaatggccgt ggtcgtgttc ttgtcgtcga tggcggtggt tctgttcgtc
     8521 gcgcactggt cgatgctgaa ctggcgcgtc tggcagtaca aaatgaatgg gaaggtctgg
     8581 tcatttacgg cgcggtgcgt caggtagatg acctggaaga gctggatatc ggcatccagg
     8641 cgatggcggc aattccggtt ggtgccgctg gcgaaggcat tggcgaaagc gatgtccgcg
     8701 tcaattttgg cggtgtcacc ttcttctccg gcgaccatct ttatgccgac aataccggga
     8761 ttattctttc agaagatccg ctggatattg aatgatagaa aaggcaccgc aaggtgcctt
     8821 ttttctgcgt tacctgttgg cctacacagt aaagaaatta cgcggaagat gaagcgtaat
     8881 cagacctctt ccatgcgacc cagcagggcc tgcagacgtt cctgccagcc gttctgctgt
     8941 tctttcagat ggttgttctc acgctccagc tcttcgcgct gatgctgggc attttgaact
     9001 tcctgcgaca gtgagttgtt tttttctttc agctcttcga tttccatctg caacagagtg
     9061 atggtatcaa tcgcctgctg tacttttgct tccagtttct caaacacttc taatgacatt
     9121 gtcatacctc tcctgaattg caaggcgttg atggataaaa atcctcgtcc cgattaccgg
     9181 tgacgcctta ataaatacga gcgcacttta gttagctccg attgtatgaa gccgcgccat
     9241 cgctgtccag cggcacgcct tgcagattac ggtttgccac acttttcatc cttctcctgg
     9301 tgacataatc cacatcaatc gaaaatgtta ataaatttgt tgcgcgaatg atctaacaaa
     9361 catgcatcat gtacaatcag atggaataaa tggcgcgata acgctcattt tatgacgaag
     9421 cacacacatt ttaagttcga tatttctcgt ttttgctcgt taacgataag tttacagcat
     9481 gcctacaagc atcgtggagg tccgtgactt tcacgcatac aacaaacatt aactcttcag
     9541 gatccgatta tgagtcaaac atcaaccttg aaaggccagt gcattgctga attcctcggt
     9601 accgggttgt tgattttttt cggtgtgggt tgcgttgcag cactaaaagt cgctggtgcg
     9661 tcttttggtc agtgggaaat cagtgtcatt tggggactgg gggtggcaat ggccatctac
     9721 ctgaccgcag gggtttccgg cgcgcatctt aatcccgctg ttaccattgc attgtggctg
     9781 tttgcctgtt tcgacaagcg caaagttatt ccttttatcg tttcacaagt tgccggcgct
     9841 ttctgcgctg cggctttagt ttacgggctt tactacaatt tatttttcga cttcgagcag
     9901 actcatcaca ttgttcgcgg cagcgttgaa agtgttgatc tggctggcac tttctctact
     9961 taccctaatc ctcatatcaa ttttgtgcag gctttcgcag ttgagatggt gattaccgct
    10021 attctgatgg ggctgatcct ggcgttaacg gacgatggca acggtgtacc acgcggccct
    10081 ttggctccct tgctgattgg tctactgatt gcggtcattg gcgcatctat gggtccattg
    10141 acgggctttg ccatgaaccc agcgcgtgac ttcggtccga aagtctttgc ctggctggcg
    10201 ggctggggca atgtcgcctt taccggcggc agagacattc cttacttcct ggtgccgctt
    10261 tttggcccta tcgttggcgc gattgtaggt gcatttgcct atcgcaaact gattggtcgc
    10321 catttgcctt gcgatatctg tgttgtggaa gaaaaggaga ccacaactcc ttcagaacaa
    10381 aaagcttcgc tgtaatatga ctacgggaca attaaacatg actgaaaaaa aatatatcgt
    10441 tgcgctcgac cagggcacca ccagctcccg cgcggtcgta atggatcacg atgccaatat
    10501 cattagcgtg tcgcagcgcg aatttgagca aatctaccca aaaccaggct gggtagaaca
    10561 cgacccaatg gaaatctggg ccacccaaag ctccacgctg gtagaagtgc tggcgaaagc
    10621 cgatatcagt tccgatcaaa ttgcagctat cggtattacg aaccagcgtg aaaccactat
    10681 tgtctgggaa aaagaaaccg gcaagcctat ctataacgcc attgtctggc agtgccgtcg
    10741 taccgcagaa atctgcgagc atttaaaacg tgacggttta gaagattata tccgcagcaa
    10801 taccggtctg gtgattgacc cgtacttttc tggcaccaaa gtgaagtgga tcctcgacca
    10861 tgtggaaggc tctcgcgagc gtgcacgtcg tggtgaattg ctgtttggta cggttgatac
    10921 gtggcttatc tggaaaatga ctcagggccg tgtccatgtg accgattaca ccaacgcctc
    10981 tcgtaccatg ttgttcaaca ttcataccct ggactgggac gacaaaatgc tggaggtgct
    11041 ggatattccg cgcgagatgc tgccagaagt gcgtcgttct tccgaagtat acggtcagac
    11101 taacattggc ggcaaaggcg gcacgcgtat tccaatctcc gggatcgccg gtgaccagca
    11161 ggcggcgctg tttggtcagt tgtgcgtgaa agaagggatg gcgaagaaca cctatggcac
    11221 tggctgcttt atgctgatga acaccggcga gaaagcggtg aaatcagaaa acggcctgct
    11281 gaccaccatc gcctgtggcc caactggcga agtaaactat gcgctggaag gtgcggtgtt
    11341 tatggcgggc gcatccattc agtggctgcg tgatgagatg aagttgatta acgacgccta
    11401 cgattccgaa tactttgcca cgaaagtgca aaacaccaat ggtgtgtatg tggttccggc
    11461 ctttaccggg ctgggtgcgc catactggga tccgtatgca cgcggggcga ttttcggtct
    11521 gactcgtggg gtgaacgcta accacattat acgcgcgacg ctggagtcta ttgcttatca
    11581 gacgcgtgac gtgctggaag cgatgcaggc cgattctggt attcgtctgc acgccctgcg
    11641 cgtggatggc ggcgcagtgg cgaacaattt cctgatgcag ttccagtccg atattctcgg
    11701 tacgcgcgtt gagcgcccgg aagtgcgcga agtcaccgca ttgggtgcgg cctatcttgc
    11761 tggtctggcg gttggcttct ggcagaacct cgacgagctg caagagaaag cggtgattga
    11821 gcgcgagttc cgtccaggca tcgaaaccac tgagcgtaat taccgttacg caggctggaa
    11881 aaaagcggtg aaacgcgcga tggcgtggga agaacacgac gagtaatgta aatgccggat
    11941 gaagcgttta tgccgcatcc ggtagtcctg aatcgtgcgg gggcaacccc gcacacatca
    12001 ataatcccgc ccttcccctg tgctacactt cgcgccattc cttactgctt agagtttgct
    12061 atgagacgag aacttgccat cgaattttcc cgcgtcaccg aatctgcggc gctggctggc
    12121 tacaaatggc taggacgcgg cgataaaaac accgcggacg gcgcagcggt aaacgccatg
    12181 cgtattatgc tcaaccaggt caacattgac ggcaccatcg ttattggtga aggtgaaatc
    12241 gacgaagcac cgatgctcta cattggtgaa aaagtcggta ctggtcgcgg cgacgcggta
    12301 gatattgctg ttgatccgat tgaaggcacg cgcatgacgg cgatgggcca ggctaacgcg
    12361 ctggcggtgc tggctgttgg cgataaaggc tgcttcctca atgcgccaga tatgtatatg
    12421 gagaagctga tcgtcggacc gggagccaaa ggcaccattg atctgaacct gccgctggcg
    12481 gataacctgc gcaatgttgc ggcggcgctc ggtaaaccgt tgagcgaact gacggtaaca
    12541 attctggcta aaccacgcca cgatgccgtt atcgctgaaa tgcagcaact cggcgtacgc
    12601 gtatttgcta ttccggacgg cgacgttgcg gcctcaattc tcacctgtat gccagacagc
    12661 gaagttgacg tgctgtacgg tattggtggc gcgccggaag gcgtggtttc tgcagcggtg
    12721 atccgcgcat tagatggtga catgaacggt cgtctgctgg cgcgtcatga cgtcaaaggc
    12781 gacaacgaag agaatcgtcg cattggcgag caggagctgg cacgctgcaa agcaatgggc
    12841 atcgaagccg gtaaagtatt gcgtctgggc gatatggcgc gcagcgataa cgtcatcttc
    12901 tctgccaccg gtattaccaa aggcgatctg ctggaaggca ttagccgcaa aggcaatatc
    12961 gcgactaccg aaacgctgct gatccgcggc aagtcacgca ctattcgccg cattcagtcc
    13021 atccactatc tggatcgcaa agacccggaa atgcaggtgc acattctctg agtgatttga
    13081 tcgattgagc cttccagtcc ttcgggactg gaattttttt gttcggagaa cgaagataag
    13141 gcaagtcaat caaaacagga gaaaaacatg gctgattggg taacaggcaa agtcactaaa
    13201 gtgcagaact ggaccgacgc cctgtttagt ctcaccgttc acgcccccgt gcttccgttt
    13261 accgccgggc aatttaccaa gcttggcctt gaaatcgacg gtgaacgcgt ccagcgcgcc
    13321 tactcctatg ttaactcgcc cgataatccc gatctggagt tttacctggt caccgtcccc
    13381 gatggcaaat taagcccacg attggcggca ctgaaaccgg gcgatgaagt gcaggtggtt
    13441 agcgaagcag ctggcttctt tgttctggat gaagtaccag attgcgaaac gctatggatg
    13501 ctggcaaccg gtacagcgat tggcccttat ctatcgattc tgcaactggg taaagattta
    13561 gatcgcttca aaaatctggt cctggttcac gccgcacgtt atgccgccga cttaagctat
    13621 ttgccactga tgcaagaact ggaaaaacgc tacgaaggca aactgcgcat tcagacggtg
    13681 gtcagtcggg aaacggctgc gggttcgctc actgggcgga taccggcgtt aattgaaagt
    13741 ggtgaactgg aaagcgcggt tggcctgccg atgaataaag aaaccagcca tgtgatgctg
    13801 tgcggcaatc cacagatggt gcgcgataca caacagttgc tgaaggagac ccggcagatg
    13861 acgaaacatt tacgtcgtcg accgggccat atgacagcgg agcattactg gtaagcggtt
    13921 acttatcgat aaacggcacg atgagcaaat ccgcactcaa cttattgatc atcccgcggt
    13981 atgccggcat caaacggttg ataaatgagt ggtgatgacc acagacaagg aggtcgcact
    14041 gctctttttg cataatttcc agcagtgttt ccggcatttc tccgcgttca atacgcagtt
    14101 ttgtcttcgg ccattgaata tttttcgtca gtttatacag cttgttatcc gacttattct
    14161 tcaacaattg aagaatatct tctgttgcag ggaagtagat acccggatac aactcgctta
    14221 agccatcatc aatatgaatt aacgtcaggt gagcgtcatt atgtctggcg agctccaggg
    14281 ctttattcac cagtaaggca tcttcttcat tcccggaaat tgccacgcca atgtgtttat
    14341 aagccatgtt taactccttc taaagcaact ccatcaagct aacgaacgca gtgataactc
    14401 aaaaataatc atctcggcct ggcatgagaa ggtgaaggcc gcatcaagct caacttgccc
    14461 ttccagatcc ttaatcttat aggctacgct ggccccttca tctgcagagg atgcagcggc
    14521 ggcaagctct ttcagtttgg tcataaagga ctctgcttct tcgcgggtgg caaaaaagcg
    14581 cgaaaactta ctggtacagt tgtcgttatc aatcaccgta ccgatatcaa tcgcacatcc
    14641 tttagtactg catttatcta cgacatcttt catagggcac ctctgtatat tcgcctctct
    14701 gtcgattacg acttaagaat aatgcgccgt taaaggaaga acaaacaagt aatgatctta
    14761 tggattacca ttttttttga tattgcttaa ggtgaagagt tcagaaggat tttccgggca
    14821 ttgtcacttg catcgtggaa ataacaatcc cggaaaaaaa tagcgataag agatatatta
    14881 aaggttaatt acttgattta ttgtcggctt tatacttcac atcctgggta tctttaccat
    14941 atttattttc gccttgtgtg ccaacaaacg caccaagatc gataagcatc atcaccagaa
    15001 tcaatgtcgg gacaaaacgc cccaccgccc attgccagac acccggtaaa atcgcccagt
    15061 tacccgccag cagcatccac gccacaatca tcagaaatgc ccatgcgccg gaacgcccgc
    15121 gatcatgcaa gcgcttaacg gttactgccg ctgttggcca aagcaagcac acaaggcaaa
    15181 acgccgcggt ctgaatatcg agtaaatttt tacccgccag tgagaaaagc accagcatgc
    15241 ctgcgaacca caggcctatc caaatccaga aatcacggcg tccaatacgc cctttaaatg
    15301 agaataacca ttgctgtatg gtcatgtaag ttccttgatg gttgtctttt ccaggattct
    15361 acccttttga caagggcgac agatatcgtt ttaatcggag ccagtcataa caaaaggtac
    15421 tgtcaatgaa gccagggtgt acgctgtttt ttctcttatg ttctgcatta accgttacaa
    15481 caacggcgca tgcacaaaca ccagatacgg caacgaccgc gccttatctg ctggctggag
    15541 cccctacttt cgatctctcc atcagccagt ttagagaaga ctttaacagc cagaatccca
    15601 gcctgccact gaacgaattt cgtgccatcg acagcagtcc cgacaaagcc aatctcactc
    15661 gtgctgccag taaaattaat gagaacttgt atgcttctac agcgctggag cgcggtacct
    15721 taaaaatcaa aagcattcaa atgacctggc tacccatcca ggggccagag caaaaagccg
    15781 cgaaagcgaa agctcaggaa tacatggcag cggtgatccg cacactcacc ccattaatga
    15841 ccaaaacaca aagccagaaa aaactgcagt cgctactaac ggcggggaaa aacaaacgtt
    15901 attacaccga gacagaaggt gcactgcgtt atgttgtcgc ggacaacggc gaaaaggggc
    15961 tgaccttcgc tgttgaaccg attaagctgg cgctatctga atcgcttgaa ggtttgaata
    16021 aatgacaaaa agcaaagcct ttgtgccgat gaatctctat actgtttcac agacctgctg
    16081 ccctgcgggg cggccatctt cctttattcg cttataagcg tggagaatta aaatgcgaca
    16141 tcctttagtg atgggtaact ggaaactgaa cggcagccgc cacatggttc acgagctggt
    16201 ttctaacctg cgtaaagagc tggcaggtgt tgctggctgt gcggttgcaa tcgcaccacc
    16261 ggaaatgtac atcgatatgg cgaagcgcga agctgaaggc agccacatca tgctgggtgc
    16321 gcaaaacgtg gacctgaatc tgtccggcgc attcaccggt gaaacctctg ctgctatgct
    16381 gaaagacatc ggcgcacagt acatcatcat cggccactct gaacgtcgta cttaccacaa
    16441 agagtctgac gaactgatcg cgaaaaaatt cgcggtgctg aaagagcagg gtctgactcc
    16501 ggttctgtgc atcggtgaaa ccgaagcgga aaacgaagcg ggcaaaactg aagaagtttg
    16561 tgcacgtcag atcgacgcgg tactgaaaac tcagggtgct gcggcattcg aaggtgcggt
    16621 tatcgcttac gaacccgtat gggcaatcgg tactggcaaa tctgcaactc cggctcaggc
    16681 acaggctgtt cacaaattca tccgtgacca cattgctaaa gttgacgcta acatcgctga
    16741 acaagtgatc atccagtacg gcggctctgt aaacgcgtct aacgctgcag aactgtttgc
    16801 tcagccagac atcgacggcg cgctggttgg cggtgcttct ctgaaagctg acgctttcgc
    16861 cgtgatcgtt aaagctgcag aagcggctaa acaggcttaa gtctggcagg tgccggattt
    16921 catatccggc acttactttc cttaactctt cgccttaacg caaaatctca cactgatgat
    16981 cctggatttc ttcggctgaa gcacggttca gcgtcagtag atttcgttgt gtcgccagca
    17041 atacaaatga gttatcactc tgccgtacca tcgccagccc gtagcttccc atatgttccc
    17101 gcgcctcagg cacttcttct gcaagcatca taaatgggct gcgttgtacc agttcgcttt
    17161 ccgttacccg acgcgccagg tactcatgcc cacgcaaacc acctggcagt ggcaaccagc
    17221 ggctactgat gttcgccaga ttgttatcca gctgttcgcg cacatcagga cgaatacaag
    17281 aaatatgaat atgaaaatgg ttttgcgtac gcccggtgcg agagttgatt gccaaagaaa
    17341 ccgcgcgatc gggaaccggc tggccgtatt ttttgctcat aaaatcacgc gcctgccagg
    17401 ccaaccaaaa gaagttcggc gttgaaggat cggtcaacaa aggactttca gtaccgttaa
    17461 tacgatacgt tggcatcaac agatattgca gtgggccatt aagatctttt aaaaccacgt
    17521 atccggcgtt gggtttgact tccgcacatg gcgaaggatt ttgattttgc tgctgattgg
    17581 gcaaacattc ctcaaggaca atcttacgta atgtatccga ctcttcaccg gttaatttcc
    17641 agtaaccaat accggcagcc acaacggcga taactatcat caccaaaaaa agaagacccg
    17701 cttttttcat ctttttttcc ctgtacctca aagagatgca agggtaacgc aaaatcgtga
    17761 caaataaaaa acccggtcgc gagaaaccac cgggtttgat aattatcctg gagaaatcag
    17821 cgtttgctga tctgatcgaa cgtaccgccg ttagcaaaat gctctttttg cgctttcgtc
    17881 cagccgccga actcttcatc aatggtgaat aacttcagct ttggaaacgc attttcgtac
    17941 tttttcgcca cctcagcatc gcgcggacgg tagtagtttt tcgcggcaat ttcctgacct
    18001 tctggcgagt agagatattt caggtaggct tccgccacct ctttggtgcc ttttttctcg
    18061 accactttat cgaccaccga cacggttggc tctgcgagga tagactcact cggcgtgacg
    18121 atttcgaatt tatctttccc cagttcattc gctgccagca gagcttcgtt ttcccaggcg
    18181 atcagtacat cgccaattcc gcgctcgaca aaagtgttag tggagccgcg cgcgccagaa
    18241 tccagaactt cgacgttttt atacagtgcc cgaacaaaat cctgtgcttt tgcctgatcg
    18301 ttgttgttgt gatgcagcgc gtagccccag gcagccaggt agttccagcg cgcgccacca
    18361 gagcttttcg gattaggcgt gatcaccgaa acacccggtt taatcagatc gttccagtca
    18421 tggatctgct tcggattgcc tttacgcacc aggaaaacaa tggtggaagt gtacggtgcg
    18481 gagttatccg gcagacgttt gatccactct ttatcaatcc gcccgcgttc cgcaattgcg
    18541 tccacgtcat aggccagagc cagagtgaca acatcagctt caataccatt gattaccgac
    18601 gtcgcttgtt tgcctgaacc accgtgggac tgacggatca ccacgttatc gccagtttgc
    18661 tgtttccagt gggcgctgaa tgccttgttg tactgttcgt acaattcgcg cgttggatca
    18721 tatgaaacgt taagaagctg aatatccttt gccataacgc tggttgccgc cagcaaaaat
    18781 gttaacccta cgccccactt gttcatcgcc cgactctctt atgttgtgtt gtgatgagca
    18841 aagcgtgcca gaaggttaac caaacattaa agaataaaaa aagattggct ataacttgcg
    18901 ggtatatgtt gagggattaa aaaggcggaa gaaatccacc tcatattgct gacaaagtgc
    18961 gctttgtcca tgccggatgc ggcgcgaacg ccttatccgg cctacaaaag tttgcaaatt
    19021 caataaattg cagaattcat gtaggcctga taagcgaagc gcatcaggca tttttgcttc
    19081 tgtcatcggt ttcaggctaa aggaatctgc ctttttccga aatcattaat acagtttttt
    19141 cgcgcagtcc agccagtcgc ctttgaacgg acgcttcatg ttttcgatag cgtcgatgat
    19201 gtcgtggtga accagctgtt cgttctggat acctacgcaa cgaccgccgt agcctgccag
    19261 cagcagatcg atagcgtaag cgcccatacg ggaagccaga atacggtcgt aaggcaccgg
    19321 agaaccaccg cgctggatgt ggcccagcac agttgcgcgg gtttcacgac cggtttcttt
    19381 ctcgatgaaa tgcgccagtt cgtcaacatc acacatatgt tcggtaatcg ccacgatcgc
    19441 gtgtttttta cctttcgcga tacccgcttt gatttcgttt accaggtctt cacggctgaa
    19501 ttcaacttcc ggaactacaa cgaattcaca gccaccagca atagccgcag ccaacgtcag
    19561 atcgccacaa taacgaccca tcacttccac cacggaaata cgctggtgag aagaagaggt
    19621 gtcacgcaga cggtcgatcg cttctacaac ggtgctcagc gcagtgaaga aaccgatagt
    19681 gtagtcagtg cctttgatgt cgttgtcgat agtgcccggc aggccgatgc acgggaagcc
    19741 catttcggtc agacgcattg cacccatgta ggaaccgtca ccgccgataa ccaccagcgc
    19801 gtcgatacca cgttttttca ggttttcgat agccacggcg cggatgttct cgtcgcggaa
    19861 ttccgggaaa cgcgcagaac cgaggaacgt accgccacgg ttgatcatgt cagaaacgct
    19921 gtaacggtct agctgtacca tacggtcttc atacagaccc agatagccgt cataaatgcc
    19981 cattacttcc agaccttctg tcagcgcaga acgaacaacc ccgcgaattg cggcgttcat
    20041 gcctggcgca tcaccgccgc ttgtcaacac accgattttc ttaatcatga ctacctctga
    20101 actttggaat gcaaaatgaa atctgttgcc ggaagtcttc ttgcacatcg aagtgatcca
    20161 acgaatgtgc aaatagtata acaatcactt cctgctgaat tgattcaggt caggccaaat
    20221 ggcggtattt tatacacaaa atgcgggtct ggctctcttt tatactgatt atgaaagcat
    20281 agaccgttta ccctccctgg gtacgacgga acaggggtcc tgatggataa tcacatccga
    20341 tcccggaaaa cgccgtaaaa tagcctgctc tacctgatcc gccaccatat gtgcctgaac
    20401 caaaggcaga gagtcttcca tttccaaatg aatctgaata aagcgggtcg gccctgactg
    20461 ccgcgtgcga agatcgtgag cgccgctaac acccggccag gaagtcacga tatcaataat
    20521 ttcttgccgt tcttcatcag gcaatgcgcg atccagtaat gactgtaccg cctcatatcc
    20581 catgcgtaac gcgctatata aaatatagat gccgattccc aatgcaaaca gagcatcggc
    20641 gcgatgccag ccgtaccagg acaaccccag cgccagcaga attgcgccgt tcatcataac
    20701 atcagactgg taatgtagca tatcagcccg caccgcctgg ctttgcgtcc ggcgcaccac
    20761 ccaccgctga aacgagacaa ggataatcgt acaaattagc gccacaattg tcacgataac
    20821 cccgacgcct ggatctgtca tcggtgttgg agataccaga tgttgaatac ccgtcaaaaa
    20881 caggaatagt gccgaaccgg agataaacat actttgcgcc agcgccgcga gggactcagc
    20941 tttaccgtga ccaaacgagt gattatcgtc ggcaggttgc agggaatatc gcaccaccag
    21001 taaattcgtc aacgacgcgc cgatatccac cagcgaatcc accagcgcgg cgagaatact
    21061 caccgacccg gtataccacc atgcaaaaat tttaatcagc aatagcagcg aagccatcgc
    21121 cgtcgcagca atcgccgccc gactgaccag ccgtccataa gattgattca taaatactcc
    21181 cgctatcaac tgacggtagt ataacggaag caaatcatct gcaatacatt aagcagcagg
    21241 caaattgagg ataaaaaaaa cccccacatc atgtggggga agacagggat ggtgtctatg
    21301 gcaaggaaaa cagggtttac tactgggaac gtgagttgct actactcaat agcttcaacg
    21361 atgaactttt ttgccattgc gtcacgtcgc gcaactgctc cattcgttgt tgatgtttct
    21421 cgtttaaaac cgcttgctgc tccggcgtta acaggcgata catttggttg cggacttttg
    21481 ccatctcaac ctgacgagca atttgctcat tcgccatttt ttctgcctgt gcgcgcacag
    21541 cgttttcatc aaaattttct gcggtgacaa ggcgatgcat tgtctccagt tcgctaacat
    21601 taacaggagg ctgttcgtgc cgggcctgtt gcataagatc tcgcatctgc tgacgctgat
    21661 gttcggttaa acttatgccg tcgaacatat ggctctgcgt actgcgctgc gtaagttctt
    21721 cacccggatg ccagttatcg cctgaaccga cttcagcagc gtggcttaat gaactgactg
    21781 ccagcgttga ggccatgacg gcagcggtaa ctatgcgcat catttgctcc caaaatcttt
    21841 ctgtcgcgat tcaacgatag agagtttacg attcaggctg caaacatgcg tcagggggtg
    21901 taaaacaacg taaagtcatg gattagcgac gtctgatgac gtaatttctg cctcggaggt
    21961 atttaaacaa tgaataaaat cctgttagtt gatgatgacc gagagctgac ttccctatta
    22021 aaggagctgc tcgagatgga aggcttcaac gtgattgttg cccacgatgg ggaacaggcg
    22081 cttgatcttc tggacgacag cattgattta cttttgcttg atgtaatgat gccgaagaaa
    22141 aatggtatcg acacattaaa agcacttcgc cagacacacc agacgcctgt cattatgttg
    22201 acggcgcgcg gcagtgaact tgatcgcgtt ctcggccttg agctgggcgc agatgactat
    22261 ctcccgaaac cgtttaatga tcgtgagctg gtggcacgta ttcgcgcgat cctgcgccgt
    22321 tcgcactgga gcgagcaaca gcaaaacaac gacaacggtt caccgacact ggaagttgat
    22381 gccttagtgc tgaatccagg ccgtcaggaa gccagcttcg acgggcaaac gctggagtta
    22441 accggcactg agtttaccct gctctatttg ctggcacagc atctgggtca ggtggtttcc
    22501 cgtgagcatt taagccagga agtgctgggc aaacgcctga cgcctttcga ccgcgctatt
    22561 gatatgcaca tttccaacct gcgtcgtaaa ctgccggatc gtaaagatgg tcacccgtgg
    22621 tttaaaacct tgcgtggtcg cggctatctg atggtttctg cttcatgata ggcagcttaa
    22681 ccgcgcgcat cttcgccatc ttctggctga cgctggcgct ggtgttgatg ttggttttga
    22741 tgttacccaa gctcgattca cgccagatga ccgagcttct ggatagcgaa cagcgtcagg
    22801 gtctgatgat tgagcagcat gtcgaagcgg agctggcgaa cgatccgccc aatgatttaa
    22861 tgtggtggcg gcgtctgttc cgggcgattg ataagtgggc accgccagga cagcgtttgt
    22921 tattggtgac caccgaaggc cgcgtgatcg gcgctgaacg cagcgaaatg cagatcattc
    22981 gtaactttat tggtcaggcc gataacgccg atcatccgca gaagaaaaag tatggccgcg
    23041 tggaactggt cggtccgttc tccgtgcgtg atggcgaaga taattaccaa ctttatctga
    23101 ttcgtccggc cagcagttct caatccgatt tcattaactt actgtttgac cgcccgctat
    23161 tactgctgat tgtcaccatg ttggtcagta cgccgcttct gttgtggttg gcctggagtc
    23221 tggcaaaacc ggcgcgtaag ctgaaaaacg ctgccgatga agttgcccag ggaaacttac
    23281 gccagcaccc ggaacttgaa gcggggccac aggaattcct tgccgctggt gccagtttta
    23341 accagatggt caccgcgctg gagcgcatga tgacctctca gcagcgtctg ctttctgata
    23401 tctctcacga gctgcgcacc ccgctgacgc gtctacaact gggtacggcg ttactgcgcc
    23461 gtcgtagcgg tgaaagcaag gaactggagc gtattgaaac cgaagcgcaa cgtctggaca
    23521 gcatgattaa cgacctgttg gtgatgtcac gtaatcagca aaaaaacgcg ctggttagcg
    23581 agaccatcaa agccaatcag ttgtggagtg aagtgctgga taacgcggcg ttcgaagccg
    23641 agcaaatggg caagtcgttg acagttaact tcccgcctgg gccgtggccg ctgtacggca
    23701 atccgaacgc ccaggaaagt gcgctggaaa acattgttcg taatgctctg cgttattccc
    23761 atacgaagat tgaagtgggc tttgcggtag ataaagacgg tatcaccatt acggtggacg
    23821 acgatggtcc tggcgttagc ccggaagatc gcgaacagat tttccgtccg ttctatcgta
    23881 ccgatgaagc acgcgatcgt gaatctggcg gtacaggttt ggggctggcg attgttgaaa
    23941 ccgccattca gcagcatcgc ggctgggtta aagcagaaga cagcccgctg ggcggtttac
    24001 ggctggtgat ttggttgccg ctgtataagc ggagttaaac tccgcattgt aggcaggata
    24061 aggcgtttac gccgcatccg gcatttgagc aggatgcctg atgcgacgct catagcgtct
    24121 tatcaggcct acactccggg ggttattttc cccacaaccg gcgggaaaaa tcttcgatct
    24181 tgccgctcag tcggcgcttt tgcatcgtcc gcgtccagct tttcgataac ccggcggcgg
    24241 agagtaaacg gtgatactga tcgtcatcaa acggcatatg ccatgcgatg gcggcagcct
    24301 cctgcacggt cacatcactg acacgggaaa ccaactccag tggcgcatca gcagatacca
    24361 accctggtgc aattacgcta tacaaccacc ccactttacc cgtgttttgc atcaactgcg
    24421 ctatgtcgct gatatcaaaa tggtaattga gtttatagca aggcgagcgc ggctggctga
    24481 cctgaattaa tgcctctccc cagcggaaaa tatcgcccat ataaacatta ctttccgtca
    24541 gaccgtcggt tgagagattt tcaccaaacg caggcgcaac aaacaactcc gcctgttccg
    24601 gaaattcccg cgcccagtag agatagtgct cacgaggata atgacacagc gctctgtctg
    24661 gcccgccgtg aaccattttc tccgcctgct cgtcaccttc cagccccagc tccgtcagca
    24721 tcaactcacc atcaacctgg attttggcaa ttgcgctggg tttgccttcg ggataagcct
    24781 gaatcttgcc tgtgtataca tcaaccggat atcgcatctg ttccctctcc acgagaaatt
    24841 tccccattaa accatattta ttttatgtca ggcgtgctgt tttcgcggta tgtatccagg
    24901 caggagctca atagcaaacc ggacgaacgt tagttcatcc ggctgtgggg attaaggaag
    24961 caggtttatt tcaccgtacc taaaatttcg attttcgccg ctctggcttt gactttacgt
    25021 gaccagatag aggtaagaat tggcaccaga atcgaagtca caatgaccgc cgtcgcgacc
    25081 agcgaagttg ctgccggagc catcggttta aacgcaggca ccatttctgc aatcagcaca
    25141 ggtgtcgcta ccgcggcccc tgcggaactg gaagcggcaa ttccggcagt gccatcgcca
    25201 ccgccaataa atttatcggc gataatcaac ggaataccgg tcacgataat tactgccaca
    25261 cccaacagga tccccagcaa acctgtctgg gcaattacag tcaaatcaat ggtattgccc
    25321 agcgcgaagg caaagaatgg aatcagcgtc tgcaccgctt tgctgaaaaa ttctcgtaat
    25381 tcagggtcaa ggttcccaag ggcaaagccc accaggaacg gtaatactgc gccgacgaaa
    25441 acatgcggtt caaacgaggc aatcccggca gtgcccagaa taatcatcgt catgagcggc
    25501 ccggactcca atgacatcaa cacaaatgcc ccagcttctt cttttgtgcc gtactgctgc
    25561 atgatggaag cgtaaagtcc gccgttggtc atatccatcg ccgccaccag cgccagcgtt
    25621 gaaagtccgg caaagaatcc aacttcaaca ccatgttccg gaataatgcg cgaggcaatt
    25681 gccgcaacca cccacgcgac ggcaattttt gttaccacca gcgtaccgga tttacgcaat
    25741 accgttcccg tcgcgcttaa ttttattgac gcccccatgc aaaaaaacca caccgccaga
    25801 atgggcaccg taccggtaat catcccgttg gtgaatgatc caaaatattt ccccgccccc
    25861 ggcgagaagg tgtggcacag tgcgccaagg aatagcggga cgagcatcat cccccccggg
    25921 attttctcaa tcgagcgttt tatctgcatt tccatcacct gtcggcatat ttttaagggc
    25981 tgatgcgtca ttcctcaacg gagcatcagt gttgatggaa acgaagataa acattcattt
    26041 gatcaataaa agtgatcaaa accacatcaa ttgaaacact gttttatttt tatcggatca
    26101 ttgtttttat tttgagattg atcacaaaaa aaccaccgcc gttggcgatg gttcattttt
    26161 taagctgata tgcggcgtaa acgcctcatt gcagcaggcg gcaaatgatt attttttcgc
    26221 cgcgaaacgt gccgctgctt cgtcccagtt aaccacgttc cagaactctt tgatgtagtc
    26281 cggacggcgg ttctggaatt tcaggtagta agcatgttcc cacacatcca ggcccagaat
    26341 cgggaagccg gaagcgccag aaatagcttc acccatcagc ggggagtcct ggttagcagt
    26401 agaaaccacc gccagtttat cgcctttcag caccagccat gcccagccgg aaccaaagcg
    26461 ggaagctgcc gctttctcaa attctgcttt gaagttatca acggagccga agtcacgttc
    26521 gatagccgct ttcaggtcac cctgcagggt ggtgcctttt ttcagacctt tccagaacag
    26581 gctgtggtta gcgtgaccgc cagcgttgtt gcgcagtacg gttttcttgt ctgctggcag
    26641 ctggtccagt ttggtgatca gctcttcaac cggcaggttg gcaaattctg gcaggttttc
    26701 cagcgccgcg ttggcgttgt tgacgtaagt ctgatggtgt ttggtgtggt ggatttccat
    26761 ggtctgctta tcgaagtgtg gttccagggc atcgtaagca tacggcaggg atggcagggt
    26821 atagctcata ttcatctcca gtattgtcgg gcggccgatt gttaatgccg cgtaagcagt
    26881 tggttcatta tagttaatta aatgatattg aaaatgatta tcaatgccgt actttttgta
    26941 agggtatggt tttgcaggaa aatgcccgag atgtgaagca aatcacccac ttaatgccgt
    27001 gattgccagt aaatcgacaa cggcggcaac aggcgaaagg ttaatcgaca gcacgatttt
    27061 tatgctcatc tcgtcggaga tgtgacgcga cgaaaaatga tgaggataag aagatgagta
    27121 acgcgattac gatggggata ttttggcatt tgatcggcgc ggccagtgca gcctgttttt
    27181 acgcgccgtt caaaaaagta aaaaaatggt catgggaaac catgtggtca gtcggtggga
    27241 ttgtttcgtg gattattctg ccgtgggcca tcagcgccct gttactaccg aatttctggg
    27301 cgtattacag ctcgtttagt ctctctacgc tgctgcctgt ttttctgttc ggcgctatgt
    27361 gggggatcgg taatatcaac tacggcctga ccatgcgtta tctcggcatg tcgatgggaa
    27421 ttggcatcgc cattggcatt acgttgattg ttggtacgct gatgacgcca attatcaacg
    27481 gcaatttcga tgttctgatt aataccgaag gcggacgcat gacgttgctc ggcgttctgg
    27541 tggcgctgat tggtgtaggg attgtgactc gcgccgggca gttgaaagag cgcaaaatgg
    27601 gcattaaagc cgaagagttc aacctgaaaa aagggctggt gctggcggtg atgtgcggca
    27661 ttttctctgc cgggatgtcc tttgcgatga acgccgcaaa accgatgcat gaagccgctg
    27721 ccgcactggg cgtcgatcca ctgtatgtcg ctctgccaag ctatgttgtc atcatgggag
    27781 gcggcgcgat catcaacctc ggtttctgct tcattcgtct ggcaaaagtg aaagatttgt
    27841 cgctaaaagc cgacttctcg ctggcaaaac cgctgatcat tcacaatgtg ttactctcag
    27901 cactgggcgg ttgatgtggt atctgcaatt ctttttctat gcctggggcc acgcccgcat
    27961 tccggcgcag tatgactaca tcagttggat gctgcatatg agcttctatg tattgtgcgg
    28021 cggtatcgtc gggctggtgc tgaaagagtg gaacaatgca ggacgccgtc cggtaacggt
    28081 gttgagcctc ggttgtgtgg tgattattgt cgccgctaac atcgtcggca tcggcatggc
    28141 gaattaatct ttctgcgaat tgagatgacg ccactggctg ggcgtcatcc cggtttcccg
    28201 ggtaaacacc accgaaaaat agttactatc ttcaaagcca cattcggtcg aaatatcact
    28261 gattaacagg cggctatgct ggaggagata ttgcgcatga cacactctga cctgccgcag
    28321 atattgattg atggtcatgc cagtctgctg gcgaaattgc tgacgcaaaa cgcgctcact
    28381 gcacgatgcc tcatcacaaa atttatccag cgcaaaggga cttttcaggc tggccgccag
    28441 ccgggtaatc agcttatcca gcaatgtttc gctggatgtt ggcggcaacg aatcgctggt
    28501 gtaacgatgg cgattcagca acatcaccaa ctgcccgaac agcaactctg ccatttcgtt
    28561 agcaaacggc acatgctgac tactttcatg ctcaagttga ccgataacct gccgcgcctg
    28621 cgccatcccc acgctaccta agcgccagtg tggttgccct gcgctggcgc taaatcccgg
    28681 aatcgctccc tgccagtcaa gattcagctt cagccgctcc gggcaataaa taatattctg
    28741 caaaaccaga tcgttaacgg aagcgtagga gtgtttatcg tcagcatgaa tgtaaaagag
    28801 atcgccacgg gtaatgcgat aagggcgatc gttgagtaca tgcagaccat taccgcgcca
    28861 gacaatcacc agctcacaaa aatcatgtgt atgttcagca aagacatctt gcggataacg
    28921 gtcagccaca gcgactgcct gctggtcgct ggcaaaaaaa tcatctttga gaagttttaa
    28981 ctgatgcgcc accgtggcta cctcggccag agaacgaagt tgattattcg caatatggcg
    29041 tacaaatacg ttgagaagat tcgcgttatt gcagaaagcc atcccgtccc tggcgaatat
    29101 cacgcggtga ccagttaaac tctcggcgaa aaagcgtcga aaagtggtta ctgtcgctaa
    29161 atccgcagcg ataggcgatg tcagtaacgc tggcctcgct gtggcgtagc agatgtcgag
    29221 ctttcatcag tcgcaggcgg ttcaggtaac gctgaggcgt cagtcccgtt ttctgcttaa
    29281 gctgccgatg tagcgtacgc agcgaaagag aaaattgatc cgccacggca tcccaattca
    29341 cctcatcggc aaaatggtcc tccagccaag ccagaagcaa gttgagacgt gacgcgctgt
    29401 tttccaggtt ctcctgcaaa ctgcttttac gcagcaagag cagtaattgc ataaataaga
    29461 tctcgcgact ggcggtcgag ggtaaatcat tttccccttc ctgctgttcc atctgtgcaa
    29521 ccagctgtcg cacctgctgc aacacgctgt ggttaacgcg ccagtgagac ggatactgcc
    29581 catcctgctc ttgtggcagc aactgattca gcccggcgag aaactgaaat cgatccggcg
    29641 agcgatacag cacattggtc agacacagat tatcggtatg ttcatacaga tgccgatcat
    29701 gatcgcgtac gaaacagacc gtcccaccgg tgatggtata gggctgccca ttaaacacat
    29761 gaatacccgt gccatgttcg acaatcacaa tttcatgaaa atcatgatga tgttcaggaa
    29821 aatccgcctg cgggagccgg ggttctatcg ccacggacgc gttaccagac ggaaaaaaat
    29881 ccacactatg taatacggtc atactggcct cctgatgtcg tcaacacggc gaaatagtaa
    29941 tcacgaggtc aggttcttac cttaaatttt cgacggaaaa ccacgtaaaa aacgtcgatt
    30001 tttcaagata cagcgtgaat tttcaggaaa tgcggtaagc atcacatcac cacaattcag
    30061 caaattgtga acatcatcac gttcatcttt ccctggttgc caatgaccca ttttcctgtc
    30121 agtaacgaga aggtcgcgaa ttcaggcgct ttttagactg gtcgtaatga aattcagcag
    30181 gatcacatta tgacctttcg caattgtgtc gccgtcgatc tcggcgcatc cagtgggcgc
    30241 gtgatgctgg cgcgttacga gcgtgaatgc cgcagcctga cgctgcgcga aatccatcgt
    30301 tttaacaatg gcctgcatag ccagaacggt tatgtcacct gggatgtgga tagcctggaa
    30361 agtgccattc gccttggatt aaacaaggtg tgcgaggaag ggattcgtat cgatagcatt
    30421 gggattgata cctggggcgt ggactttgtg ctgctcgacc tacagggtaa gcgtgtgggt
    30481 ctgcccgttg cttatcgcga tagccgcacc catggcctga tgacgcaggc acaacagcaa
    30541 ctcggcaaac gcgatattta tcagcgtagc ggcatccagt ttctgccctt caatacgctt
    30601 tatcagttgc gtgcgctgac ggagcaacaa cctgagctta ttccacacat tgctcacgct
    30661 ctgctgatgc cggattactt cagttatcgc ctgaccggca agatgaactg ggagtacacc
    30721 aacgccacga ccacgcaact ggtcaatatt aatagcgacg actgggacga gtcgctactg
    30781 gcgtggagcg gggccaacaa agcctggttt ggtcacccga cgcatccggg taatgtcatt
    30841 gggcactgga tttgcccgca aggtaatgag attcctgtcg tcgccgttgc cagccatgac
    30901 accgccagcg cggttatcgc ctcgccgtta aacggttcac gcgccgctta tctctcttct
    30961 ggcacctggt cattgatggg cttcgaaagc cagacaccat ttaccaatga cacggcgctg
    31021 gcagccaaca tcaccaatga aggcggggcg gaaggtcgct atcgggtgct gaaaaatatt
    31081 atgggcttat ggctgcttca gcgggtgctt caggagcggc aaatcaacga tcttccggcg
    31141 cttatcgccg cgacacaggc acttccggcc tgccgcttca tcatcaatcc caatgacgat
    31201 cgctttatta atcctgacga gatgtgcagc gaaattcagg ctgcgtgtcg ggaaacagcg
    31261 caaccaatcc cggaaagtaa tgctgaactg gcgcgctgta ttttcgacag tctggcgttg
    31321 ctgtatgccg atgtgttgca tgagctggcg cagctacgcg gtgaagattt ctcgcaactg
    31381 catattgtcg gcggaggctg ccagaacacg ctgcttaacc agttatgtgc tgatgcctgc
    31441 ggtattcggg tgatcgccgg gcctgttgaa gcctcgacgc tcggcaatat cggcatccag
    31501 ttaatgacgc tggatgaact caacaatgtg gatgatttcc gtcaggtcgt cagcaccacc
    31561 gcgaatctga ccacctttac ccctaatcct gacagtgaaa ttgcccacta tgtggcgcgg
    31621 attcactcta cacgacagac aaaggagctt tgcgcatgac cactcaactg gaacaggcct
    31681 gggagctggc gaaacagcgt ttcgcggcgg tggggattga tgtcgaggag gcgctgcgcc
    31741 aacttgatcg tttacccgtt tcaatgcact gctggcaggg cgatgatgtt tccggttttg
    31801 aaaacccgga aggttcgctg accggtggga ttcaggccac tggtaattat ccgggcaaag
    31861 cgcgtaatgc cagtgagctg cgtgccgatc tggaacaggc tatgcggctg attccggggc
    31921 cgaaacggct taatttacat gccatctatc tggaatcaga cacgccagtc tcgcgcgacc
    31981 aaatcaaacc agagcacttc aaaaactggg ttgaatgggc gaaagccaat cagctcggtc
    32041 tggattttaa cccctcctgt ttttcgcatc cgctaagcgc cgatggcttt acgctttccc
    32101 atgccgacga cagtattcgc cagttctgga ttgatcactg caaagccagc cgccgtgttt
    32161 cagcctattt tggcgagcaa cttggcacac cgtcggtgat gaacatctgg atcccggatg
    32221 gcatgaaaga tatcaccgtt gaccgtctcg ccccacgtca gcgtttgctg gcagcactgg
    32281 atgaggtgat cagcgagaag ctggatccgg cgcaccatat cgacgccgtt gagagcaaat
    32341 tatttggtat tggtgcggag agctacacgg ttggctccaa tgagttttac atggggtatg
    32401 ccaccagccg ccagacggcg ctgtgcctgg atgccggaca tttccacccg actgaagtga
    32461 tttccgacaa gatttccgcc gccatgctgt atgtgccgca gttgctgctg cacgtcagcc
    32521 gtccggttcg ctgggacagc gatcacgtag tgctactgga tgatgaaact caggcgattg
    32581 ccagtgagat tgttcgtcac gatctgttcg accgggtaca tatcggtctc gatttctttg
    32641 atgcctctat caaccgcatt gccgcatggg tcattggtac gcgcaatatg aaaaaagccc
    32701 tgctgcgtgc gttgctggaa cctaccgctg agctacgcaa gctggaagcg gcgggcgatt
    32761 acactgcgcg tctggcgcta ctggaagagc agaaatcgtt gccgtggcag gcggtatggg
    32821 aaatgtattg tcagcgtcac gatacgccag cgggtagcga atggctggag aacgtgcgga
    32881 cttatgagaa agaaattttg agtcgccgcg ggtaaacact gccggatgcg gcacaagtgc
    32941 cttatccggc ctacgggtcg gcaatagttg taggcctgat aagacgcgac agcgtcgcat
    33001 caggcattga ttgccggatg cggcacgagc gccatatccg gcctacgggt cggcaatagt
    33061 tgtaggcctg ataagacgcg acagcgtcgc atcaggcatt gattgccgga tgcggcacga
    33121 gtgccttatc cggcctacag atcgtacatc cggcaacagg cacggacgtc caattaacag
    33181 gaacacagaa catgcaaaac attacccagt cctggtttgt ccagggaatg atcaaagcca
    33241 ccaccgacgc ctggctgaaa ggctgggacg agcgcaatgg tggtaacctg acgctgcgcc
    33301 tggatgacgc cgatatcgcg ccttatcacg gcaactttca tgcacaaccg cgctatatcc
    33361 cgctcatcca gcccatgcct ttactggcaa atacaccgtt tattgtcacc ggctccggca
    33421 aattctttcg taacgtccag cttgatcctg cggctaactt aggcgtcgta aaagtcgaca
    33481 gcgacggcgc gggctaccat attctctggg ggctaaccaa cgaagccgtt ccaacctctg
    33541 aacttccggc tcactttctc tcccactgcg agcgcattaa agccaccaac ggtaaagatc
    33601 gggtgatcat gcactgccac gccaccaacc tgatcgccct tacctacgta ctggaaaacg
    33661 acaccgcgct cttcactcgc cagctttggg aaggcagcac cgagtgtctg gtagtgttcc
    33721 cggatggcgt cggcattttg ccgtggatgg tgcccggcac ggacgaaatc ggccaggcga
    33781 ccgcacagga aatgcaaaaa cattcgctgg tgttgtggcc cttccacggc gtcttcggca
    33841 gcggtccgac actggatgaa acattcggtt taatcgacac cgcagaaaaa tcagcacaag
    33901 tattagtgaa ggtttattcg atgggcggca tgaaacagac catcagtcgt gaagagctga
    33961 tagcgctcgg ccagcgtttc ggtgttacac cactcgccag tgcgctggcg ctgtaaggag
    34021 caaacatgat ccgcaaagcc tttgtcatgc aggttaaccc cgacgcccac gaagagtatc
    34081 agcgtcggca taatccaatc tggccggaac tggaagcagt gttgaaatct cacggtgcac
    34141 ataactacgc catttacctc gacaaagcgc gtaatctgct gtttgccacg gtagagattg
    34201 aatctgaaga acggtggaat gcggtagcca gtactgatgt ttgccaacgt tggtggaaat
    34261 atatgaccga cgttatgcca gctaacccgg ataacagccc agtcagtagc gagctgcaag
    34321 aagtgtttta cctgccttaa tgagttgcgg tgccggaaaa tatccagcac cgcgccttca
    34381 tcagaagaag tatttaaagc gaacgcgtgc gccgtaacgg tcatcagtat catcaccgtg
    34441 ttttttatca ccgtcgctat ccagaatgga gtaataagta ccaaggtaaa tattaaagtt
    34501 ctccatatcc atcacattag caaactgata agacgcatga atggtgtgaa tggtgtacgt
    34561 cccttcatca tcaatccagc agtcgttatc acaaactaca ccgctgaatt catcaatctt
    34621 attgtgcgcg tagatataac ccagctcgaa acgtttccac agcgcgttaa tcccggcagt
    34681 gaaatctttt tcattattag catctaaata ggcggtatta agattaacca cgacgccatt
    34741 ttccggatcc gtttttaggc cattccaggt catgctcata ccatagcctg tacgatcgga
    34801 ctgatcgaca aaattaccct tgctatcggt ataaccataa gcattattta ccacgttcgc
    34861 ttccatcgct gcggaaacgg tgaattcttc tgtcggcgac caggcaatta ccggacgcag
    34921 ataagcaaca tttttctgct gctccatatc gcgtccatga taattaccgt cattatataa
    34981 agatgttccg tcttcaagta acgtgtttaa ctcaaaatac cagttatcaa gttgtttgct
    35041 gacgaggaaa ttaccgccag cgttagagcg cccgcggccc tctttcatca tatagatata
    35101 accgctgcca tcgtcataaa gatcgttcgc agtattaccg gaatgttcaa caaaggtatc
    35161 ctgattcagc gggaacatat cgtaggcttc aaaacggcct actttgacct tccagtcgtt
    35221 ttctttgcca aagaagaata ccgcatcatc gatatttact gaaccgtgca tatcccccag
    35281 cggttgtgcg gagaacccgg cgaaatagcc attatccagt tttcgcatac catcaaaacc
    35341 taacagaata cgaccattga gattccactg ttcattagtg ggatcgctat tcacatcagc
    35401 gttggtcatt gccagcaggc catgattact ttccgcatcc atattaaatt ctacgtcgcc
    35461 gtagattttt aaatcgccat aacctgagag caaaagatta ggtgaggtgg aatttttctt
    35521 tgcagattcc gccgttgcct gtccatttac cggcgtattg ccctgggcag ccttaatttc
    35581 gcggatctca gcggcttgtt gtgtctgcag ctgtttaacc tggctctctg cttttgctgc
    35641 ccgcatttct gccgcttcca ggcgttcttc cagcaatgcc atgcgttgtt ccagcgttaa
    35701 atgctgtgtt tttgccattc cggtactaca tgccaataat aaaccgatgg ctaaagataa
    35761 tgtcgatttt ttcattattt acgttccctg aaataaaaga gaccctacgc tttccaaaag
    35821 gaatacgtat atagagaaat ataaggtgtg cactttcgaa tttttaatcc aacttcagca
    35881 ggccgatgga tagtatcccg ctgcataata tgagtaaatc cgctgatttc ctggaacgtg
    35941 aggaatataa caatagtgcc gtttttaacc aaatatcgta aaaaatatta gatataattc
    36001 acgctgactc ataagccaca aatataaata accttgctgc aaaacatgtg cggcagttaa
    36061 acattcacaa catcatta
//
LOCUS       DADXDL010000050        35664 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.050, whole genome shotgun sequence.
ACCESSION   DADXDL010000050 DADXDL010000000
VERSION     DADXDL010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 35664)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35664)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35664
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.050"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            107..2335
                     /gene="crfC"
                     /locus_tag="IRB70_002720"
     CDS             107..2335
                     /gene="crfC"
                     /locus_tag="IRB70_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="clamp-binding protein CrfC"
                     /protein_id="HBC0632615.1"
                     /translation="MYTQTLYELSQEAERLLQLSRQQLQLLEKMPLSVPGDDAPQLAL
                     PWSQPNIAERHAMLNNELRKISRLEMVLAIVGTMKAGKSTTINAIVGTEVLPNRNRPM
                     TALPTLIRHTPGQKEPVLHFSHVAPIDCLIQKLQQRLRDCDIKHLTDVLEIDKDMRAL
                     MQRIENGVAFEKYYLGAQPIFHCLKSLNDLVRLAKALDVDFPFSAYAAIEHIPVIEVE
                     FVHLAGLESYPGQLTLLDTPGPNEAGQPHLQKMLSQQLARASAVLAVLDYTQLKSISD
                     EEVREAILAVGQSVPLYVLVNKFDQQDRNSDDADQVRALISGTLMKGCITPQQIFPVS
                     SMWGYLANRARHELANNGKLPPPEQQRWVEDFAHAALGRRWRHADLADLEHIRHAADQ
                     LWEDSLFAKPIQALLHAAYANASLYALRSAAHKLLNYAQQAREYLDFRAHGLNVACEQ
                     LRQNIHQIEESLQLLQLNQAQVSGEIKHEIELALTSANHFLRQQQDALNAQLAALFQD
                     DSEPLSEIRTRCETLLQTAQNTICRDFTLRFAELESTLCRVLTDVIRPIEQQIKMELS
                     ESGFRPGFHFPVFHGAVPHFNTRQLFSEVISRQEATDEQSTRLGVVRDTFSRWLNQPD
                     WGRGNEKSPTETVDYSVLQRALSAEVDLYCQQMAKVLAEQVDESVTAGMNTFFAEFAS
                     CLTELQTRLRESLALRQQNESVVRLMQQQLQQTVMTHGWIYTDAQLLRDDIQTLFTAE
                     RY"
     gene            2332..3210
                     /locus_tag="IRB70_002721"
     CDS             2332..3210
                     /locus_tag="IRB70_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418534.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcZ-like family protein"
                     /protein_id="HBC0632616.1"
                     /translation="MTKTLLDGPGRVLESIHSRFLVDLAQGDDARHPQAHQQQFRERL
                     MQELLARVQLQAWTNGGMLNAPLSLRLTLVEKLASMLDPGHLALTQIAQHLALLQKMD
                     HRQHSAFPELPQQIAALYEWFSARCRWKEKALTQRGLLVQAGEQSEQIFTRWRAGAYN
                     AWSLPGRCFIVLEELRWGAFGDACRLGSPQAVALLLGDLREKATQHLAESINAAPTTR
                     HYYHQWFASSTVPTGGEHADFLSWLGKWTTADKQPVCWSVTQRWQTVALGMPRLCSAQ
                     RLAGAMVEEIFSVNLA"
     gene            3474..4976
                     /gene="proP"
                     /locus_tag="IRB70_002722"
     CDS             3474..4976
                     /gene="proP"
                     /locus_tag="IRB70_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline transporter ProP"
                     /protein_id="HBC0632617.1"
                     /translation="MLKRKKVKPITLRDVTIIDDGKLRKAITAASLGNAMEWFDFGVY
                     GFVAYALGKVFFPGADPSVQMVAALATFSVPFLIRPLGGLFFGMLGDKYGRQKILAIT
                     IVIMSISTFCIGLIPSYDTIGIWAPILLLICKMAQGFSVGGEYTGASIFVAEYSPDRK
                     RGFMGSWLDFGSIAGFVLGAGVVVLISTIVGEANFLDWGWRIPFFIALPLGIIGLYLR
                     HALEETPAFQQHVDKLEQGDREGLQDGPKVSFKEIATKYWRSLLTCIGLVIATNVTYY
                     MLLTYMPSYLSHNLHYSEDHGVLIIIAIMIGMLFVQPVMGLLSDRFGRRPFVLLGSVA
                     LFVLAIPAFILINSNVIGLIFAGLLMLAVILNCFTGVMASTLPAMFPTHIRYSALAAA
                     FNISVLVAGLTPTLAAWLVESSQNLMMPAYYLMVVAVVGLITGVTMKETANRPLKGAT
                     PAASDIQEAKEILVEHYDNIEQKIDDIDHEIADLQAKRTRLVQQHPRIDE"
     gene            5088..5177
                     /gene="pmrR"
                     /locus_tag="IRB70_002723"
     CDS             5088..5177
                     /gene="pmrR"
                     /locus_tag="IRB70_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000797656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LpxT activity modulator PmrR"
                     /protein_id="HBC0632618.1"
                     /translation="MKNRVYESLTTVFSVLVVSSFLYIWFTTY"
     gene            complement(5153..6253)
                     /gene="pmrB"
                     /locus_tag="IRB70_002724"
     CDS             complement(5153..6253)
                     /gene="pmrB"
                     /locus_tag="IRB70_002724"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     PmrB"
                     /protein_id="HBC0632619.1"
                     /translation="MNLMRFLRRPISLRQRLILTIGAILLVFELISVFWLWHESTEQI
                     QLFEQALRDNRNNDRHIMREIREAVASLIVPGVFMVSLTLFICYQAVRRITRPLAELQ
                     KELEARTADNLTPIAIHSATLEIEAVVSALNDLVSRLTSTLDNERLFTADVAHELRTP
                     LAGVRLHLELLAKTHHIDVAPLVARLDQMMESVSQLLQLARAGQSFSSGNYQHVKLLE
                     DVILPSYDELSTMLDQRQQTLLLPESAADITVQGDATLLRMLLRNLVENAHRYSPQGS
                     NIMIKLQEDGGAVMAVEDEGPGIDESKCGELSKAFVRMDSRYGGIGLGLSIVSRITQL
                     HHGQFFLQNRQETSGTRAWVRLKKDQYVVNQI"
     gene            complement(6254..6922)
                     /gene="basR"
                     /locus_tag="IRB70_002725"
     CDS             complement(6254..6922)
                     /gene="basR"
                     /locus_tag="IRB70_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator BasR"
                     /protein_id="HBC0632620.1"
                     /translation="MKILIVEDDTLLLQGLILAAQTEGYACDGVTTARMAEQSLEAGH
                     YSLVVLDLGLPDEDGLHFLARIRQKKYTLPVLILTARDTLTDKIAGLDVGADDYLVKP
                     FALEELHARIRALLRRHNNQGESELIVGNLTLNMGRRQVWMGGEELILTPKEYALLSR
                     LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKARIRTVRGFGYMLVA
                     NEEN"
     gene            complement(6919..8562)
                     /gene="eptA"
                     /locus_tag="IRB70_002726"
     CDS             complement(6919..8562)
                     /gene="eptA"
                     /locus_tag="IRB70_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418538.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase EptA"
                     /protein_id="HBC0632621.1"
                     /translation="MLKRLLKRPSLNLLAWLLLAAFYISICLNIAFFKQVLQALPLDS
                     LHNVLVFLSMPVVAFSVINIVLTLSSFLWLNRPLACLFILVGAAAQYFIMTYGIVIDR
                     SMIANIIDTTPAESYALMTPQMLLTLGFSGVLAALIACWIKIKPATSRLRSVLFRGAN
                     ILVSVLLILLVAALFYKDYASLFRNNKELVKSLSPSNSIVASWSWYSHQRLANLPLVR
                     IGEDAHRNPLMQNEKRKNLTILIVGETSRAENFSLNGYPRETNPRLAKDNVVYFPNTA
                     SCGTATAVSVPCMFSDMPREHYKEELAQHQEGVLDIIQRAGINVLWNDNDGGCKGVCD
                     RVPHQNVTALNLPGQCINGECYDEVLFHGLEDYINNLQGDGVIVLHTIGSHGPTYYNR
                     YPPQFRKFTPTCDTNEIQTCTKEQLVNTYDNTLVYVDYIVDKAINLLKEHQDKFTTSL
                     VYLSDHGESLGENGIYLHGLPYAIAPDSQKQVPMLLWLSEDYQKRYQVDQNCLQKQAQ
                     TQHYSQDNLFSTLLGLTGVETKYYQAADDILQTCRRVSE"
     gene            complement(8666..10003)
                     /gene="adiC"
                     /locus_tag="IRB70_002727"
     CDS             complement(8666..10003)
                     /gene="adiC"
                     /locus_tag="IRB70_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine/agmatine antiporter"
                     /protein_id="HBC0632622.1"
                     /translation="MSSDADAHKVGLIPVTLMVSGNIMGSGVFLLPANLASTGGIAIY
                     GWLVTIIGALGLSMVYAKMSFLDPSPGGSYAYARRCFGPFLGYQTNVLYWLACWIGNI
                     AMVVIGVGYLSYFFPILKDPLILTITCVVVLWIFVLLNIVGPKMITRVQAVATVLALI
                     PIVGIAVFGWFWFRGETYMAAWNVSGLGTFGAIQSTLNVTLWSFIGVESASVAAGVVK
                     NPKRNVPIATIGGVLIAAVCYVLSTTAIMGMIPNAALRVSASPFGDAARMALGDTAGA
                     IVSFCAAAGCLGSLGGWTLLAGQTAKAAADDGLFPPIFARVNKAGTPVAGLIIVGILM
                     TIFQLSSISPNATKEFGLVSSVSVIFTLVPYLYTCAALLLLGHGHFGKARPAYLAVTT
                     IAFLYCIWAVVGSGAKEVMWSFVTLMVITAMYALNYNRLHKNPYPLDAPISKD"
     gene            complement(10140..10901)
                     /gene="adiY"
                     /locus_tag="IRB70_002728"
     CDS             complement(10140..10901)
                     /gene="adiY"
                     /locus_tag="IRB70_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator AdiY"
                     /protein_id="HBC0632623.1"
                     /translation="MRICSDQPCIVLLTEKDVWIRVNGKEPISLKANHMALLNCENNI
                     IDVSSLNNTLVAHISHDIIKDYLRFLNKDLSQIPVWQRSATPILTLPCLTPDVFRVAA
                     QHSMMPAETESEKERTRALLFTVLSRFLDSKKFLSLMMYMLRNCVSDSVYQIIESDIH
                     KDWNLSMVASCLCLSPSLLKKKLKSENTSYSQIITTCRMRYAVNELMMDGKNISQVSQ
                     SCGYNSTSYFISVFKDFYGMTPLHYVSQHRERTVA"
     gene            complement(11237..13504)
                     /gene="adiA"
                     /locus_tag="IRB70_002729"
     CDS             complement(11237..13504)
                     /gene="adiA"
                     /locus_tag="IRB70_002729"
                     /EC_number="4.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418541.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine decarboxylase"
                     /protein_id="HBC0632624.1"
                     /translation="MKVLIVESEFLHQDTWVGNAVERLADALSQQNVTVIKSTSFDDG
                     FAILSSNEAIDCLMFSYQMEHPDEHQNVRQLIGKLHERQQNVPVFLLGDREKALAAMD
                     RDLLELVDEFAWILEDTADFIAGRAVAAMTRYRQQLLPPLFSALMKYSDIHEYSWAAP
                     GHQGGVGFTKTPAGRFYHDYYGENLFRTDMGIERTSLGSLLDHTGAFGESEKYAARVF
                     GADRSWSVVVGTSGSNRTIMQACMTDNDVVVVDRNCHKSIEQGLMLTGAKPVYMVPSR
                     NRYGIIGPIYPQEMQPETLQKKINESPLTKDKAGQKPSYCVVTNCTYDGVCYNAKEAQ
                     DLLEKTSDRLHFDEAWYGYARFNPIYADHYAMRGEPGDHNGPTVFATHSTHKLLNALS
                     QASYIHVREGRGAINFSRFNQAYMMHATTSPLYAICASNDVAVSMMDGNSGLSLTQEV
                     IDEAVDFRQAMARLYKEFTADGSWFFKPWNKEVVTDPQTGKTYDFADAPTKLLTTVQD
                     CWVMHPGESWHGFKDIPDNWSMLDPIKVSILAPGMGEDGELEETGVPAALVTAWLGRH
                     GIVPTRTTDFQIMFLFSMGVTRGKWGTLVNTLCSFKRHYDANTPLAQVMPELVEQYPD
                     TYANMGIHDLGDTMFAWLKENNPGARLNEAYSGLPVAEITPREAYNAIVNNNVELVSI
                     ENLPGRIAANSVIPYPPGIPMLLSGENFGDKNSPQVSYLRSLQSWDHHFPGFEHETEG
                     TEIIDGIYHVMCVKA"
     gene            complement(13703..14611)
                     /gene="melR"
                     /locus_tag="IRB70_002730"
     CDS             complement(13703..14611)
                     /gene="melR"
                     /locus_tag="IRB70_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator MelR"
                     /protein_id="HBC0632625.1"
                     /translation="MNTDTFMCSSDEKQTRSPLSLYSEYQRMEIEFRAPHIMPTSHWH
                     GQVEVNVPFDGDVEYLINNEKVSINQGHITLFWACTPHQLTDTGTCQSMAIFNLPMHL
                     FLSWPLDKDLINHVTHGMVIKSLATQQLSPFEVRRWQQELNSPNEQIRQLAIDEIGLM
                     LKRFSLSGWEPILVNKTSRTHKNSVSRHAQFYVSQMLGFIAENYDQALTINDVAEHVK
                     LNANYAMGIFQRVMQLTMKQYITAMRINHVRALLSDTDKSILDIALTAGFRSSSRFYS
                     TFGKYVGMSPQQYRKLSQQRRQAFPG"
     gene            14894..16249
                     /gene="melA"
                     /locus_tag="IRB70_002731"
     CDS             14894..16249
                     /gene="melA"
                     /locus_tag="IRB70_002731"
                     /EC_number="3.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBC0632626.1"
                     /translation="MMSAPKITFIGAGSTIFVKNILGDVFHREALKTAHIALMDIDPT
                     RLEESHIVVRKLMDSAGASGKITCHTQQKEALQDADFVVVAFQIGGYEPCTVTDFEVC
                     KRHGLEQTIADTLGPGGIMRALRTIPHLWQICEDMTEVCPDATMLNYVNPMAMNTWAM
                     YARYPHIKQVGLCHSVQGTAEELARDLNIDPATLRYRCAGINHMAFYLELERKTADGS
                     YVNLYPELLAAYEAGQAPKPNIHGNTRCQNIVRYEMFKKLGYFVTESSEHFAEYTPWF
                     IKPGREDLIERYKVPLDEYPKRCVEQLANWHKELEEYKNASRIDIKPSREYASTIMNA
                     IWTGEPSVIYGNVRNDGLIDNLPQGCCVEVACLVDANGIQPTKAGTLPSHLAALMQTN
                     INVQTLLTEAILTENRDRVYHAAMMDPHTAAVLGIDEIYALVDDLIAAHGDWLPGWLH
                     R"
     gene            complement(16246..16896)
                     /locus_tag="IRB70_002732"
     CDS             complement(16246..16896)
                     /locus_tag="IRB70_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000198764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2238 domain-containing protein"
                     /protein_id="HBC0632627.1"
                     /translation="MPRTLKPLILNTGALALTLILIYTGILANDKLTWLMEVTPVIIV
                     VPLLLATAKRYPLTPLLYTLIFFHAIILMVGGQYTYAKVPVGFEVQEWLGLSRNPYDK
                     LGHFFQGLVPALVAREILVRGMYVRGRKMVAFLVCCVALAISAMYELIEWWAALAMGQ
                     GADDFLGTQGDQWDTQSDMFCALLGALTTVIFLARFHCRQLRRFGLITRAPEAITS"
     gene            complement(17019..18665)
                     /gene="fumB"
                     /locus_tag="IRB70_002733"
     CDS             complement(17019..18665)
                     /gene="fumB"
                     /locus_tag="IRB70_002733"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HBC0632628.1"
                     /translation="MSNKPFIYQAPFPMGKDNTEYYLLTSDYVSVADFDGETILKVEP
                     EALTLLAQQAFHDASFMLRPAHQKQVAAILHDPEASENDKYVALQFLRNSEIAAKGVL
                     PTCQDTGTAIIVGKKGQRVWTGGGDEEALSKGVYNTYIEDNLRYSQNAPLDMYKEVNT
                     GTNLPAQIDLYAVDGDEYKFLCVAKGGGSANKTYLYQETKALLTPGKLKNFLVEKMRT
                     LGTAACPPYHIAFVIGGTSAETNLKTVKLASAHYYDELPTEGNEHGQAFRDIQLEQEL
                     LEEAQKLGLGAQFGGKYFAHDIRVIRLPRHGASCPVGMGVSCSADRNIKAKINREGIW
                     IEKLEHNPGQYIPEELRKAGEGEAVKVDLNRPMKEILAQLSQYPVSTRLSLTGTIIVG
                     RDIAHAKLKELIDAGKELPQYIKDHPIYYAGPAKTPAGYPSGSLGPTTAGRMDSYVDL
                     LQSHGGSMIMLAKGNRSQQVTDACHKHGGFYLGSIGGPAAVLAQQSIKHLECVAYPEL
                     GMEAIWKIEVEDFPAFILVDDKGNDFFQQIVNKQCANCTK"
     gene            complement(18743..20083)
                     /gene="dcuB"
                     /locus_tag="IRB70_002734"
     CDS             complement(18743..20083)
                     /gene="dcuB"
                     /locus_tag="IRB70_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic C4-dicarboxylate transporter DcuB"
                     /protein_id="HBC0632629.1"
                     /translation="MLFTIQLIIILICLFYGARKGGIALGLLGGIGLVILVFVFHLQP
                     GKPPVDVMLVIIAVVAASATLQASGGLDVMLQIAEKLLRRNPKYVSIVAPFVTCTLTI
                     LCGTGHVVYTILPIIYDVAIKNNIRPERPMAASSIGAQMGIIASPVSVAVVSLVAMLG
                     NVTFDGRHLEFLDLLAITIPSTLIGILAIGIFSWFRGKDLDKDEEFQKFISVPENREY
                     VYGDTATLLDKKLPKSNWLAMWIFLGAIAVVALLGADSDLRPSFGGKPLSMVLVIQMF
                     MLLTGALIIILTKTNPASISKNEVFRSGMIAIVAVYGIAWMAETMFGAHMSEIQGVLG
                     EMVKEYPWAYAIVLLLVSKFVNSQAAALAAIVPVALAIGVDPAYIVASAPACYGYYIL
                     PTYPSDLAAIQFDRSGTTHIGRFVINHSFILPGLIGVSVSCVFGWIFAAMYGFL"
     gene            complement(20654..21373)
                     /gene="dcuR"
                     /locus_tag="IRB70_002735"
     CDS             complement(20654..21373)
                     /gene="dcuR"
                     /locus_tag="IRB70_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator DcuR"
                     /protein_id="HBC0632630.1"
                     /translation="MINVLIIDDDAMVAELNRRYVAQIPGFQCCGTASTLEKAKEIIF
                     NSDTPIDLILLDIYMQKENGLDLLPVLHNARCKSDVIVISSAADAATIKDSLHYGVVD
                     YLIKPFQASRFEEALTGWRQKKMALEKHQYYDQAELDQLIHGSSSNEQDPRRLPKGLT
                     PQTLRTLCQWIDAHQDYEFSTDELANEVNISRVSCRKYLIWLVNCHILFTSIHYGVTG
                     RPVYRYRIQAEHYSLLKQYCQ"
     gene            complement(21370..23001)
                     /gene="dcuS"
                     /locus_tag="IRB70_002736"
     CDS             complement(21370..23001)
                     /gene="dcuS"
                     /locus_tag="IRB70_002736"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     DcuS"
                     /protein_id="HBC0632631.1"
                     /translation="MRHSLPYRILRKRPMKLSTTVILMVSAVLFSVLLVVHLIYFSQI
                     SDMTRDGLANKALAVARTLADSPEIRQGLQKKPQESGIQAIAEAVRKRNDLLFIVVTD
                     MQSLRYSHPEAQRIGQPFKGDDILKALNGEENVAINRGFLAQALRVFTPIYDENHKQI
                     GVVAIGLELSRVTQQINDSRWSIIWSVLFGMLVGLIGTCILVKVLKKILFGLEPYEIS
                     TLFEQRQAMLQSIKEGVVAVDDRGEVTLINDAAQELLNYRKSQDDEKLSTLSHSWSQV
                     VDVSEVLRDGTPRRDEEITIKDRLLLINTVPVRSNGVIIGAISTFRDKTEVRKLMQRL
                     DGLVNYADALRERSHEFMNKLHVILGLLHLKSYKQLEDYILKTANNYQEEIGSLLGKI
                     KSPVIAGFLISKINRATDLGHTLILNSESQLPDSGSEDQVTTLITTLGNLIENALEAL
                     GPEPGGEISVTLHYRHGWLHCEVNDDGPGIAPDKIDHIFDKGVSTKGSERGVGLALVK
                     QQVENLGGSIAVESEPGIFTQFFVQIPWDGERSNR"
     gene            23182..23412
                     /locus_tag="IRB70_002737"
     CDS             23182..23412
                     /locus_tag="IRB70_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4Fe-4S)-binding protein"
                     /protein_id="HBC0632632.1"
                     /translation="MDQALLDGGYRCYTGENIDVYFNTAICQHSGNCVRGNGKLFNLK
                     RKPWIMPDEVDVTTVVKVIDMCPSGALKYRHK"
     gene            23424..23696
                     /locus_tag="IRB70_002738"
     CDS             23424..23696
                     /locus_tag="IRB70_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBC0632633.1"
                     /translation="MEIREGHNKFYINDEQGKQIAEIVFVPTGENLAIIEHTDVDESL
                     KGQGIGKQLVAKVVEKMRREKRKIIPLCPFAKHEFDKTREYDDIRS"
     gene            23925..24221
                     /gene="ghoS"
                     /locus_tag="IRB70_002739"
     CDS             23925..24221
                     /gene="ghoS"
                     /locus_tag="IRB70_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HBC0632634.1"
                     /translation="MEGKNKFNTYVVSFDYPSSYSSVFLRLRSLMYDMNFSSIVADEY
                     GIPRQLNENSFAITTSLAASEIEDLIRLKCLDLPDIDFDLNIMTVDDYFRQFYK"
     gene            24249..24422
                     /gene="ghoT"
                     /locus_tag="IRB70_002740"
     CDS             24249..24422
                     /gene="ghoT"
                     /locus_tag="IRB70_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system toxin GhoT"
                     /protein_id="HBC0632635.1"
                     /translation="MALFSKILIFYVIGVNISFVIIWFISHEKTHIRLLSAFLVGITW
                     PMSLPVALLFSLF"
     gene            complement(24541..26058)
                     /gene="lysS"
                     /locus_tag="IRB70_002741"
     CDS             complement(24541..26058)
                     /gene="lysS"
                     /locus_tag="IRB70_002741"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBC0632636.1"
                     /translation="MSERETRGANEAIDFNDELRNRREKLAALRQQGVAFPNDFRRDH
                     TSDQLHEEFDAKDNQELEALNIEVSVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     SLPEGVYNDQFKKWDLGDIIGARGTLFKTQTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEVRYRQRYLDLIANDKSRQTFVVRSKILAAIRQFMVARGFMEVETPMMQVIPGGA
                     SARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYHDLIELTESLFRTLAQEVLGATKVTYGEHVFDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDAAKALAESIGITVEKSWGLGRIVTEIFDEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAERFQEQVNAKAAG
                     DDEAMFYDEDYVTALEYGLPPTAGLGIGIDRMIMLFTNSHTIRDVILFPAMRPQK"
     gene            complement(26295..27752)
                     /gene="dtpC"
                     /locus_tag="IRB70_002742"
     CDS             complement(26295..27752)
                     /gene="dtpC"
                     /locus_tag="IRB70_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpC"
                     /protein_id="HBC0632637.1"
                     /translation="MKTPSQPRAIYYIVAIQIWEYFSFYGMRALLILYLTHQLGFDDN
                     HAISLFSAYASLVYVTPILGGWLADRLLGNRTAVIAGALLMTLGHVVLGIDTNSTFSL
                     YLALAIIICGYGLFKSNISCLLGELYDENDHRRDGGFSLLYAAGNIGSIAAPIACGLA
                     AQWYGWHVGFALAGGGMFIGLLIFLSGHRHFQSTRSMDKKALTSVKFALPVWSWLVVM
                     LCLAPVFFTLLLENDWSGYLLAIVCLIAAQIIARMMIKYPEHRRALWQIVLLMLVGTL
                     FWVLAQQGGSTISLFIDRFVNRQAFNIEVPTALFQSVNAIAVMLAGVVLAWLASPESR
                     GNSALRVWLKFAFGLLLMACGFMLLAFDARHAAAGGQASMGVMISGLALMGFAELFID
                     PVAIAQITRLKMSGVLTGIYMLATGAVANWLAGVVAQQTTESQISGMAIAAYQRFFSQ
                     MGEWTLACVAIIVVLAFATRFLFSTPTNMIQESND"
     gene            complement(27811..29958)
                     /gene="cadA"
                     /locus_tag="IRB70_002743"
     CDS             complement(27811..29958)
                     /gene="cadA"
                     /locus_tag="IRB70_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylase CadA"
                     /protein_id="HBC0632638.1"
                     /translation="MNVIAILNHMGVYFKEEPIRELHRALERLNFQIVYPNDRDDLLK
                     LIENNARLCGVIFDWDKYNLELCEEISKMNENLPLYAFANTYSTLDVSLNDLRLQISF
                     FEYALGAADDIANKIKQTTDEYINTILPPLTKALFKYVREGKYTFCTPGHMGGTAFQK
                     SPVGSLFYDFFGPNTMKSDISISVSELGSLLDHSGPHKEAEQYIARVFNADRSYMVTN
                     GTSTANKIVGMYSAPAGSTILIDRNCHKSLTHLMMMSDVTPIYFRPTRNAYGILGGIP
                     QSEFQHATIAKRVKETPNATWPVHAVITNSTYDGLLYNTDFIKKTLDVKSIHFDSAWV
                     PYTNFSPIYEGKCGMSGGRVEGKVIYETQSTHKLLAAFSQASMIHVKGDVNEETFNEA
                     YMMHTTTSPHYGIVASTETAAAMMKGNAGKRLINGSIERAIKFRKEIKRLRTESDGWF
                     FDVWQPDHIDTTECWPLRSDSTWHGFKNIDNEHMYLDPIKVTLLTPGMEKDGTMSDFG
                     IPASIVAKYLDEHGIVVEKTGPYNLLFLFSIGIDKTKALSLLRALTDFKRAFDLNLRV
                     KNMLPSLYREDPEFYENMRIQELAQNIHKLIVHHNLPDLMYRAFEVLPTMVMTPYAAF
                     QKELHGMTEEVYLDEMVGRINANMILPYPPGVPLVMPGEMITEESRPVLEFLQMLCEI
                     GAHYPGFETDIHGAYRQADGRYTVKVLKEESKK"
     gene            complement(30038..31372)
                     /gene="cadB"
                     /locus_tag="IRB70_002744"
     CDS             complement(30038..31372)
                     /gene="cadB"
                     /locus_tag="IRB70_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadaverine/lysine antiporter"
                     /protein_id="HBC0632639.1"
                     /translation="MSSAKKIGLFACTGVVAGNMMGSGIALLPANLASIGGIAIWGWI
                     ISIIGAMSLAYVYARLATKNPQQGGPIAYAGEISPAFGFQTGVLYYHANWIGNLAIGI
                     TAVSYLSTFFPVLNDPVPAGIACIAIVWVFTFVNMLGGTWVSRLTTIGLVLVLIPVVM
                     TAIVGWHWFDAATYAANWNTADTTDGHAIIKSILLCLWAFVGVESAAVSTGMVKNPKR
                     TVPLATMLGTGLAGIVYIAATQVLSGMYPSSVMAASGAPFAISASTILGNWAAPLVSA
                     FTAFACLTSLGSWMMLVGQAGVRAANDGNFPKVYGEVDSNGIPKKGLLLAAVKMTALM
                     ILITLMNSAGGKASDLFGELTGIAVLLTMLPYFYSCVDLIRFEGVNIRNFVSLICSVL
                     GCVFCFIALMGASSFELAGTFIVSLIILMFYARKMHERQSHSMDNHTASNAH"
     gene            complement(31738..33276)
                     /gene="cadC"
                     /locus_tag="IRB70_002745"
     CDS             complement(31738..33276)
                     /gene="cadC"
                     /locus_tag="IRB70_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine decarboxylation/transport transcriptional
                     activator CadC"
                     /protein_id="HBC0632640.1"
                     /translation="MQQPVVRVGEWLVTPSINQISRNGRQLTLEPRLIDLLVFFAQHS
                     GEVLSRDELIDNVWKRSIVTNHVVTQSISELRKSLKDNDEDSPVYIATVPKRGYKLMV
                     PVIWYSEEEGEEIMLSSPPPIPEAVPATDSPSHSLNIQNTATPPEQSPVKSKRFTTFW
                     VWFFFLLSLGICVALVAFSSLETRLPMSKSRILLNPRDIDINMVNKSCNSWSSPYQLS
                     YAIGVGDLVATSLNTFSTFMVHDKINYNIDEPSSSGKTLSIAFVNQRQYRAQQCFMSV
                     KLVDNADGSTMLDKRYVITNGNQLAIQNDLLESLSKALNQPWPQRMQETLQQILPHRG
                     ALLTNFYQAHDYLLHGDDKSLNRASELLGEIVQSSPEFTYARAEKALVDIVRHSQHPL
                     DEKQLAALNTEIDNIVTLPELNNLSIIYQIKAVSALVKGKTDESYQAINTGIDLEMSW
                     LNYVLLGKVYEMKGMNREAADAYLTAFNLRPGANTLYWIENGIFQTSVPYVVPYLDKF
                     LASE"
     gene            complement(34025..34867)
                     /locus_tag="IRB70_002746"
     CDS             complement(34025..34867)
                     /locus_tag="IRB70_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4942 domain-containing protein"
                     /protein_id="HBC0632641.1"
                     /translation="MSEITVSRPEVVNGHTDVICSTSVSHILAVRKSTLLQIDILIRQ
                     LAEISAMTESIGGKTALDWAMKQDFRCGCWLMEKPETAMKAITRNLDREIWRDLMQRS
                     GMLSLMDAQTRDTWYRSLEYDNFPEISEANIMSTFEQLHQNKDEVFERGVINVFRGLS
                     WNYKTNSPCKFGSKIIVNNLVRWGRWGFHLITGPQTDRVADLERMLHLFSGIPTPDNR
                     ENIIIRLDEHIRSVQGKEYYEDEMFIIKYFKKGSAHITFKRLELIDRINDIIVRHFPS
                     VLSA"
     gene            complement(34952..35146)
                     /locus_tag="IRB70_002747"
     CDS             complement(34952..35146)
                     /locus_tag="IRB70_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001560290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HBC0632642.1"
                     /translation="MPLATETALDILIVWLQDNIDCESGIIFDNDEDKTDSAALLPCI
                     EQAREDIHTLRQLQLLHQNR"
     gene            complement(35225..35374)
                     /locus_tag="IRB70_002748"
                     /pseudo
     CDS             complement(35225..35374)
                     /locus_tag="IRB70_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708774.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(35371..>35664)
                     /locus_tag="IRB70_002749"
     CDS             complement(35371..>35664)
                     /locus_tag="IRB70_002749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HBC0632643.1"
                     /translation="LLDQHYGLTLNDTPFADERVIEQHIEAGIALCDAVNFLVEKYAL
                     VRTDQPGFSAGTSSQLINSIDILRARRATGLMTRSNYRTVNNITRGKHPEAKQ"
BASE COUNT         9069 a         8571 c         8910 g         9114 t
ORIGIN      
        1 taaatataaa attatttctt gcagtaatta taaaagccga aaacagaact caaaagcaat
       61 ctggctaaat aaaagtaata aaatttgctt taaggaagaa ttttctatgt acacacagac
      121 cctgtatgag ttaagtcagg aggctgaacg cctgttacag ctttctcgcc aacagttgca
      181 gttactggaa aaaatgcctc tctctgtacc cggagacgat gcgccacaac tggctttacc
      241 ctggagtcag cctaatatcg ccgaacgtca cgcgatgctg aataatgagt tgcgtaaaat
      301 ttcccgactg gaaatggtgc tggcgattgt cggtaccatg aaagcaggga aatcaaccac
      361 cattaatgcc attgttggta cggaggttct gcctaatcgc aatcgcccaa tgactgcact
      421 gccgacgctt attcgccata cgcccgggca aaaagaaccg gtactgcatt tttcacatgt
      481 cgcgccaatc gattgtttaa ttcaaaaatt acaacagcgc ctgcgtgatt gcgatattaa
      541 gcatctgacc gatgtgctgg aaatagataa agatatgcgt gcgcttatgc agcggatcga
      601 aaatggcgtc gctttcgaaa aatattatct gggtgcccag cctatttttc attgtctgaa
      661 aagtttgaat gatttggtgc gactggcgaa ggcgctggac gtcgattttc ctttttctgc
      721 ttacgccgcc attgagcata ttcccgtgat tgaagtggag tttgtccatc tggcggggct
      781 ggagagttat cccggtcaat tgacgttact ggataccccc gggccaaatg aagccgggca
      841 accgcatctg caaaaaatgc ttagccagca gctggcacgc gcctcggcgg tactggcggt
      901 gctggattat acgcaactga aatcgatctc cgatgaagag gtccgtgagg cgattttggc
      961 ggtggggcaa tcggtgccgc tgtatgtgct ggtcaataag ttcgatcaac aggatcgtaa
     1021 cagtgacgac gccgaccagg tgcgggcact gatttccggg acgctgatga aaggctgtat
     1081 tacgccacag cagatatttc cggtgtcgtc gatgtggggc tacctggcga atcgggcgcg
     1141 ccatgagtta gccaacaacg gtaagttacc accgccagag caacaacgct gggtggaaga
     1201 ttttgcccat gccgcgctcg gcaggcgctg gcgtcatgcc gatctggcgg acctcgaaca
     1261 tattcgtcat gctgccgatc agttgtggga agattcgctg ttcgccaagc caattcaggc
     1321 gttgcttcat gccgcttacg ctaacgcctc gttgtatgct ctgcgatctg ccgcgcataa
     1381 actgttgaat tacgcgcagc aggcgcggga atacctggat tttcgtgcgc acgggttaaa
     1441 cgtcgcttgt gaacaattgc ggcaaaatat ccatcagatc gaagaaagtt tgcagctatt
     1501 gcaactcaat caggcgcagg tgagcggcga gattaaacat gaaatcgagc tggccctgac
     1561 ctccgccaac cactttctgc gtcaacagca agatgcgctg aatgcacagt tagccgcgtt
     1621 gtttcaggat gattcggagc cgttaagcga gattcgtacc cgctgtgaga cactgttaca
     1681 gacggcgcag aacaccatct gtcgcgactt tacgctgcgt tttgccgagc tggaatccac
     1741 cctttgccgg gtgttaaccg atgttattcg ccccattgag caacaaatca aaatggaatt
     1801 gagcgagtca gggtttcgtc ctgggtttca ttttcctgtt tttcacggcg cagttcccca
     1861 cttcaacact cgccagctgt tcagtgaagt catttcgcgc caggaagcaa cggacgagca
     1921 gagcacgcgt ttaggcgttg tgcgtgacac tttttcgcgc tggttgaatc agcccgactg
     1981 gggacgggga aatgagaaat ccccgacaga gacggttgat tacagtgtgt tgcaacgagc
     2041 attaagcgca gaagtcgatc tttattgcca acaaatggct aaagttctgg cagagcaggt
     2101 cgatgaatct gttacggcag gcatgaatac ttttttcgct gagttcgctt catgtttgac
     2161 ggaattacag acgcgtttac gcgaaagcct ggctctgcgt caacaaaatg aatcggtggt
     2221 caggctgatg cagcagcaat tgcagcagac tgtgatgact catggctgga tttacaccga
     2281 cgctcagctg ttacgcgatg atattcaaac acttttcacg gcagaacgat attgaccaag
     2341 acgttactgg acggccccgg tcgcgtgctg gagtcgattc attcccgctt tttagtggat
     2401 ctggcgcagg gcgatgatgc ccgccatcca caagcccatc agcagcagtt tcgtgaacga
     2461 ctgatgcagg aacttcttgc gcgtgtgcag cttcaggcat ggacgaacgg cggcatgtta
     2521 aatgcgccgc ttagcctgcg tctgacattg gtggaaaaac tggcgtcgat gctggatccc
     2581 ggtcatctgg cgctgacgca gatcgcgcag catctggcgc tgctgcaaaa aatggatcac
     2641 cgccagcact ctgctttccc ggagctcccc cagcaaattg ccgccttgta tgagtggttt
     2701 tcagcccgtt gtcgctggaa ggaaaaggcg ttaacgcaac gaggcctact ggtgcaggca
     2761 ggtgaacaga gcgagcaaat ttttacccgc tggcgtgctg gggcgtacaa cgcctggtcg
     2821 ttgcctgggc gctgttttat cgttctggag gagttgcgtt ggggggcatt tggcgatgcc
     2881 tgccgtctgg gaagcccgca agcggtggcg ttgttgctgg gtgatttgcg cgagaaagcg
     2941 acacaacatc tggcagagag tatcaatgcg gcaccgacca cgcgtcacta ttaccatcag
     3001 tggtttgcct cttcgaccgt tccgacgggc ggggagcatg ctgatttttt aagttggctg
     3061 ggaaagtgga ccacggcaga taaacaaccc gtttgctggt cagtgaccca acgctggcaa
     3121 actgtcgcac tggggatgcc acgactctgt tcagcgcagc gtctggcggg ggcaatggtc
     3181 gaggaaatct tctctgtaaa tttggcgtaa ataatcagtt acatcaatga gtcctaaacg
     3241 aaatccatgt gtgaagttga tcacaaattt aaacactggt agggtaaaaa ggtcattaac
     3301 tgcccaattc aggcgtcaac tggtttgatt gtacattcct taaccggagg gtgtaagcaa
     3361 acccgctacg cttgttacag agattgcatc ctgcaattcc cgctcccctt ttgcggccgt
     3421 cgcgctgatt tttctggcgt ttgcggaaat gggccaactc tgcgaggaaa gctatgctga
     3481 aaaggaaaaa agtaaaaccg attacccttc gtgatgtcac tattattgat gacggtaaac
     3541 tgcgtaaagc cattaccgca gcatcactgg gtaatgcaat ggaatggttc gattttggtg
     3601 tttatggttt tgttgcttac gcattaggta aagttttttt cccgggggct gaccccagcg
     3661 tgcagatggt tgctgcactt gccactttct ccgttccctt tctgattcga ccgcttggcg
     3721 ggctcttctt tggtatgttg ggcgataaat atggtcgcca gaagatcctc gctatcacta
     3781 ttgtgattat gtcgatcagt acgttctgta ttggcttaat accgtcctac gacacgattg
     3841 gtatttgggc accgattctg ctgttgatct gtaagatggc acaaggtttc tcggtcggcg
     3901 gtgaatatac cggggcgtcg atatttgttg cggaatactc ccctgaccgt aaacgtggat
     3961 ttatgggcag ctggctggac ttcggttcta ttgccgggtt tgtgctgggt gcgggcgtgg
     4021 tggtgttaat ttcgaccatt gtcggcgaag cgaacttcct cgactggggc tggcgtattc
     4081 cgttctttat tgctctgccg ttagggatta tcgggcttta cctgcgccat gcgctggaag
     4141 agactccggc gttccagcag catgttgata aactggaaca gggcgaccgc gaaggtttgc
     4201 aggatggccc gaaagtctcg tttaaagaga ttgccactaa atactggcgc agcctgttga
     4261 catgtattgg tctggtaatt gccaccaacg tgacttacta catgttgctg acctatatgc
     4321 cgagttattt gtcgcataac ctgcattact ccgaagacca cggggtgctg attattatcg
     4381 ccattatgat cggtatgctg tttgtccagc cggtgatggg cttgctgagt gaccgttttg
     4441 gccgtcgtcc gtttgtgcta cttggtagtg ttgcactgtt tgtgttggcg atcccggcgt
     4501 ttattctgat taacagtaac gtcatcggcc tgatttttgc cgggttactg atgctggcgg
     4561 tgattcttaa ctgctttacg ggcgttatgg cttctacctt gccagcgatg ttcccgacgc
     4621 atatccgtta cagcgcgctg gcggcggcat ttaatatttc ggtgctggtt gccggtctga
     4681 cgccaacact ggcggcctgg ctggtcgaaa gctcgcagaa tctgatgatg cctgcctatt
     4741 acctgatggt agtggcggtg gttggtttaa tcaccggcgt aaccatgaaa gagacggcaa
     4801 atcgtccgtt gaaaggtgcg acaccggcgg cgtcagatat acaggaagcg aaggaaattc
     4861 tcgtcgagca ttacgataat atcgagcaga aaatcgatga tattgaccac gagattgccg
     4921 atttgcaggc gaaacgtacc cgcctggtgc agcaacatcc gcgaattgat gaataagctg
     4981 aaacggatgg cctgatgtga cgctgtctta tcaggccaat tgaactctta aggttcactt
     5041 aatctctgac gcgcatactc tcctccaggt taacggagga gagtgcaatg aaaaaccgtg
     5101 tttatgaaag tttaactacc gtgtttagcg tgctggtggt cagcagcttt ctttatatct
     5161 ggtttaccac gtactgatct ttcttcagcc gtacccaggc ccgcgtgccg gaagtctctt
     5221 gccggttttg caggaaaaac tgcccgtgat gcaactgtgt aatgcggctg acaatactta
     5281 accccagacc aatcccgcca taacggctgt ccatacgtac aaacgcttta ctcaactccc
     5341 cgcatttact ctcatcaata cccggtcctt catcttcaac tgccatgacc gctccgccat
     5401 cttcttgcag cttaatcata atgttgctgc cttgcgggct gtaacgatgg gcgttttcta
     5461 ccaggtttcg caataacatc cgcagcaggg ttgcatcacc ctgaacggtg atgtcggcgg
     5521 cgctctctgg caatagcagg gtttgctgtc gctggtcgag catggtactg agttcgtcat
     5581 acgaggggag aatgacatct tccagcagtt ttacatgttg ataattcccg gaagaaaatg
     5641 actgtccggc acgcgccagt tgcagcaact gggagacact ctccatcatc tgatcaagtc
     5701 gagccactaa cggtgctaca tcaatgtgat gcgttttcgc cagcagttcc agatgcaaac
     5761 gcacccccgc cagtggcgtt cgcagttcgt gcgcgacgtc agcggtaaac aacctttcgt
     5821 tatccagcgt gctggtcagg cgactgacca gatcgtttaa cgctgaaacc accgcttcga
     5881 tttcgagggt ggcgctgtga atggcaatgg gtgttaagtt gtcggcggtg cgcgcttcca
     5941 gctctttttg cagctccgcc agcgggcggg tgatgcggcg taccgcctga tagcagataa
     6001 atagcgtcag gctgaccata aagacgccgg ggacaatcag gctggcgacc gcctcgcgga
     6061 tctcacgcat gatgtggcga tcgttgttgc gattgtcgcg tagcgcctgc tcaaacagct
     6121 gaatctgctc ggtactttca tgccatagcc agaagacgct gatcagctca aacaccaaca
     6181 aaatggcccc gatggtcaat atcagccgtt ggcgcagcga tattggtcgg cgcagaaaac
     6241 gcatcagatt caattagttt tcctcatttg cgaccagcat atagccaaat ccgcgcacgg
     6301 tgcggatacg ggctttgccc actttgtctc gcagattgtg gatatgcact tccagggtgt
     6361 tggtcgaggg ttcattgtcc cagttataga tgtcgttgta gagaatttcc cgatgcaccg
     6421 ggctgcctgc tttgagcatt aaccgtgaca gcagagcata ttctttgggc gtcagaatca
     6481 actcttcacc gcccatccat acctgacggc gacccatatt cagcgtcaga ttgccaacaa
     6541 tcagctcact ttcgccctga ttattatggc gtcgtagcag ggcgcggata cgggcgtgta
     6601 actcttccag cgcaaaaggc ttcaccagat agtcatcggc accgacatcc agcccggcga
     6661 ttttgtcggt cagcgtatcg cgagcggtga ggatcagtac cggcagggtg tattttttct
     6721 gccggatacg ggcgagaaaa tgcagtccat cttcgtcggg taaccctaaa tccagtacca
     6781 ccaggctgta atgaccggcc tcaaggcttt gttccgccat ccgcgcggtt gtcacgccat
     6841 cgcacgcgta gccttcggtt tgcgccgcca gaatcaatcc ctgcaataac agcgtatcgt
     6901 cttcaacaat cagaattttc attcactcac tctcctgcaa gtttgcagaa tatcatccgc
     6961 agcctggtaa tacttcgtct caacgccagt taatcccaat agcgtggaga ataaattgtc
     7021 ttgtgaatag tgttgtgttt gcgcctgttt ttgcagacag ttctggtcaa cctgataccg
     7081 tttttgataa tcctccgaca gccacagcag catcggcacc tgtttttggc tatccggggc
     7141 gatggcataa ggcagaccgt gcagatagat gccattttca cctaacgatt caccgtggtc
     7201 agaaagataa accaggctgg tggtaaattt atcctgatgt tctttcagca gattaatcgc
     7261 tttatcaaca atatagtcga cgtaaaccag cgtgttgtcg taagtgttca ccagttgctc
     7321 tttggtacag gtctggatct cattggtgtc gcaggttggg gtaaatttcc tgaactgcgg
     7381 cggatagcgg ttgtaatagg tcgggccgtg gctgccgatg gtgtgtaaga caatcacgcc
     7441 atcaccctgc aggttattga tgtaatcttc cagcccgtgg aacagtactt catcatagca
     7501 ctcgccgttg atgcactgac caggcaggtt cagcgcggtg acgttctggt gaggtacgcg
     7561 atcgcaaacg cctttacagc cgccatcgtt gtcattccac agcacgttga tgcccgctcg
     7621 ctgaatgata tccagcacgc cttcctggtg ctgtgccaac tcttctttgt aatgctcacg
     7681 cggcatatcc gagaacatgc acggtactga aactgccgtt gccgtgccgc aagatgcggt
     7741 attagggaaa tagaccacgt tatctttcgc cagccgcggg ttagtttcac gcgggtagcc
     7801 gttgagggag aagttctccg cccgcgaggt ttcgccgaca atcaggatgg tcaaattttt
     7861 acgtttctcg ttctgcatta acgggttgcg gtgcgcgtct tcaccaattc gcaccagcgg
     7921 cagatttgcc agtcgctgat gggagtacca tgaccagctg gcaacaatgc tgttagaggg
     7981 gcttaaggac ttcaccagct ctttgttgtt gcggaacaac gaggcgtagt ctttataaaa
     8041 cagtgcggcg accagcaaaa tcagcagtac agaaaccaga atattggcac cacggaaaag
     8101 aacactgcgc agacgcgagg tggcaggttt gattttaatc cagcaggcaa tcagcgcagc
     8161 aagcacgccg ctgaatccca gcgttaataa catttgcggt gtcatcagcg cataactttc
     8221 tgccggagtg gtatcaataa tattggcaat catcgagcgg tcgatgacga tgccgtaagt
     8281 cattatgaaa tattgtgcag ccgcgccaac cagaataaac aggcaggcca gcggtcgatt
     8341 aagccataag aaagagctta gtgtcaggac aatattaatc acgctgaaag cgacgaccgg
     8401 catcgacaag aaaaccagta cgttatgcag cgagtccagc ggcagtgcct gcaacacctg
     8461 tttaaaaaag gcaatattca ggcagataga gatataaaaa gcggccaaca atagccaggc
     8521 gagtaaattc aaagagggtc tttttagtag gcgcttcaac atcacggtgt ttccatcgaa
     8581 caaagtgcgc atatgctcgc aaagcaaaat taagccaacc ttaagttctt aaggttggct
     8641 tttatgtttg ctggattaag gggaattaat ctttgcttat tggtgcatct aagggatacg
     8701 ggtttttatg cagccggttg taattcagcg catacatggc ggtgatgacc atcagggtga
     8761 caaatgacca cataacctct ttcgccccgg accccaccac ggcccagatg cagtagagga
     8821 aggcaatggt agtcactgcc agatatgccg ggcgtgcttt accaaagtga ccgtgtccga
     8881 gcagcagtaa cgccgcacag gtgtaaagat atggcaccag tgtaaagatg accgacacgg
     8941 aagacaccag accgaactct ttagtcgcgt ttggcgaaat gctactgagc tggaagatgg
     9001 tcatcaaaat accgacgata atcagccctg ccactggcgt acccgcttta tttacacggg
     9061 caaaaatcgg tgggaacagt ccgtcatcgg cagcggcttt cgccgtttga cccgccagca
     9121 acgtccagcc gcccagtgaa cctaagcaac ccgcagctgc gcagaaggaa acaatggccc
     9181 cggcggtgtc acccaacgcc atccgtgcgg catcaccgaa tggcgaggca gaaacgcgca
     9241 gtgcggcatt agggatcatc cccataatcg cggtggtgga gagcacatag caaacggcgg
     9301 caatcaatac cccaccaatg gtggcgatag ggacgttgcg tttcgggttt ttcaccacac
     9361 ctgcggcaac ggaggcactt tccacaccga tgaacgacca cagcgtaacg ttaagggtac
     9421 tttgaatcgc gccgaaggtg cccaggccgc tgacgttcca tgccgccata taggtttcac
     9481 cacggaacca gaaccagcca aatacggcaa tcccgacgat ggggatcagc gccagcacgg
     9541 tggcaacggc ctgcacgcgg gtgatcattt tcggaccgac aatgttcagc aggacgaaga
     9601 tccacagcac cacgacgcag gtgatggtta atatcagtgg atctttcaga atcgggaaga
     9661 agtaacttaa atatcctacg ccaatgacca ccatggcgat attgccgatc cagcaggcca
     9721 gccagtagag gacgttggtt tgataaccga gaaacgggcc aaagcagcgg cgggcgtaag
     9781 cgtaagaacc accaggactt gggtcgagga acgacatttt ggcgtatacc atcgagagcc
     9841 ccagcgcacc gataatcgtc accaaccatc cataaatggc aatcccgcca gtggaggcca
     9901 ggtttgcagg taacagaaaa acacctgacc ccataatatt ccccgacacc atcagggtga
     9961 cggggattaa gcccactttg tgagcatcag catccgaaga cataattaaa ctcctgcgaa
    10021 ggcgagcttc gtgacaataa attacgtcat atcatacgcc tgcattcgat agttgaatta
    10081 ttatcgaccg ggttatcgct gatgccgtta ttaatatagc tcttcgttaa ggttaaaaat
    10141 caggcgacag tgcgttctct gtgctgacta acataatgca gaggcgtcat accgtagaag
    10201 tctttaaaga cagaaataaa gtacgacgta ctgttgtagc cacacgactg tgagacctga
    10261 gagatatttt taccgtccat cattaattca tttacggcat aacgcatgcg gcaggtggtg
    10321 attatttggc tataactggt gttttcgctt ttcagctttt tctttaacag acttgggcta
    10381 agacataaac aactggctac catactaaga ttccagtctt tgtggatatc gctttcaata
    10441 atttgataaa cgctgtcact tacacaatta cgtaacatat acatcattag tgaaaggaat
    10501 tttttactgt cgagaaaacg ggatagcaca gtgaataata atgcacgtgt tcgttccttt
    10561 tctgactcag tttcagcggg catcatgcta tgttgcgcgg caacgcgaaa gacgtctggc
    10621 gtcaggcatg gcagggtgag gatgggcgta gcgctacgtt gccatactgg tatttgcgag
    10681 agatctttat tcaaaaaccg gaggtaatct ttgatgatgt cgtgactaat atgagcaacc
    10741 aaagtgttat taagagagga gacgtcgata atattatttt cacaatttaa taacgccatg
    10801 tggttagctt taaggctaat aggttctttc ccattcaccc ttatccagac atctttttca
    10861 gtcaataaaa caatacaagg ttggtcgctg caaatcctca tacatgtact cctgagtgcg
    10921 aataaaagac cagttctcgc taaagcgaag cgataccggg aaatggttat ataattgtat
    10981 gatgaatata aacatgcata aaaataacga gttttactaa tattacaaat ttttatagta
    11041 atttctcatg tacatatttt tttacaggct aaaaaaagga taaataacag gcaaaaaaaa
    11101 gcgcggggtg ggaccgcgca aaaagtatga cattttttgt ttgcagcaat ttttatgaaa
    11161 acgttgccat acttaaaagg cctcaagcca ggcggcgtaa tgttatttaa caattacgcc
    11221 ttcagcggaa tagtggttac gctttcacac acataacgtg gtaaataccg tcaataattt
    11281 ctgtcccttc tgtttcgtgt tcaaatccag ggaaatgatg gtcccaggat tgcagcgagc
    11341 gtaaataact tacttgcgga ctgtttttat cgccgaagtt ttcaccagac agcagcatcg
    11401 ggattcctgg cggatacggg ataactgagt ttgccgcgat acgtcctggc agattttcaa
    11461 tggataccag ttcgacattg ttgttgacaa tcgcgttgta cgcttcacgc ggggtgattt
    11521 ccgccaccgg taggccggaa taggcttcat tcaaccgtgc gccagggttg ttttctttca
    11581 gccaggcaaa catggtgtca cccagatcgt gaatccccat gttcgcgtaa gtgtcaggat
    11641 attgttcaac aagttccggc atcacctgcg ccagcggtgt gttggcatca tagtggcgtt
    11701 tgaaggagca aagggtgtta accagagtcc cccatttccc acgggttacg cccatagaaa
    11761 acaggaacat aatttggaag tcagtggtgc gggtaggcac aatgccgtgg cgaccaagcc
    11821 aggcagtgac cagcgccgcc ggaacaccgg tttcttccag ttcaccatct tcacccattc
    11881 ccggagcaag gatgctgact ttaatcgggt cgagcatact ccagttatcc ggaatatctt
    11941 tgaagccgtg ccagctttcg ccaggatgca tgacccagca gtcctgaacg gtggtcagca
    12001 gtttggttgg tgcgtcagca aagtcatagg ttttgccggt ttgtgggtcg gtgacgactt
    12061 ctttgttcca cggtttgaag aaccagctac cgtcagcggt gaactcttta tacagccgcg
    12121 ccatcgcctg acggaaatca accgcttcgt cgatcacttc ctgggtcagt gacaggccgc
    12181 tgttgccgtc catcatcgac accgccacgt cgttggatgc gcagatggca tacagcgggg
    12241 aggtggtggc atgcatcatg taggcctggt tgaagcggga gaagttaatc gccccacgac
    12301 cttcacgtac atgaatataa gaggcctgtg acagcgcatt cagcagtttg tgggtggagt
    12361 gggtggcgaa aacggtagga ccgttgtgat cgccaggttc gccgcgcatg gcatagtgat
    12421 cggcatagat cgggttgaaa cgtgcatagc cgtaccaggc ttcgtcaaag tgcagacgat
    12481 cggaggtttt ttccagcaga tcctgtgctt ctttagcgtt ataacacacg ccgtcatagg
    12541 tgcagttggt caccacgcag taagacggtt tttgcccggc tttgtcttta gtcagcgggc
    12601 tttcattgat tttcttctgc aaggtttcag gttgcatttc ctgcggatag attggcccga
    12661 taatgccgta gcggttgcgg cttggcacca tgtagaccgg tttcgcgcct gtcagcatca
    12721 agccttgttc gatggattta tggcagttac ggtcaacgac cacgacatcg ttatcggtca
    12781 tgcaagcctg catgatggtg cggttagagc cggaagtacc gacgactacc gaccaggagc
    12841 gatcggcacc aaatacgcgt gcggcatatt tttcgctttc gccaaatgcg ccagtatggt
    12901 caagcaaaga accgagggaa gtccgttcga tgcccatgtc ggtgcggaac agattttcac
    12961 catagtagtc atggtagaaa cgtccggcgg gtgttttggt aaaaccaacg ccaccctggt
    13021 ggcctggcgc tgcccaggaa tattcatgga tgtcgctata tttcatcagc gcgctgaaca
    13081 gtggcggcaa cagctgctgg cggtagcggg tcatcgcggc aacggcgcgt ccggcgataa
    13141 agtcggcggt atcttccaga atccaggcga attcatcgac aagctccagc agatcccggt
    13201 ccattgcggc gagggctttt tcccgatcgc ccaacaggaa gaccggcacg ttttgttggc
    13261 gctcatgaag cttaccgatc aattgtctga cgttttgatg ttcgtccgga tgttccattt
    13321 gatagctgaa catcaggcag tcaatggctt cgtttgaaga gagaatggca aaaccatcat
    13381 caaaggaggt ggatttaatc acggtaacat tttgctggct taaagcatct gccagacgct
    13441 caacggcgtt accgacccag gtgtcttgat ggagaaactc gctttcaaca attaatactt
    13501 tcatcattgc ttacccggtt atgaaggaat cttcgttgcg ggcaagtatc ttccggcctt
    13561 ttcgggctgt aaagcgcgtg aaaaacaaac atttttgaaa tatttgattt tataaacaac
    13621 atgttatgtg attattttaa attattttca ctgcttatta tcgacggcta aactattttt
    13681 ttggctgata ctgatatcgt ctttagccgg gaaacgcctg gcggcgttgt tggctaagtt
    13741 tgcggtattg ttgcggcgac atgccgacat atttgccgaa cgtgctgtaa aaacggctac
    13801 tcgaacgaaa gcctgccgtc agggcaatat cgagaatact tttatcggta tcgctcagta
    13861 acgcgcgaac gtggttgatg cgcatcgcgg taatgtactg tttcattgtc aattgcatga
    13921 cccgctggaa tatccccatt gcatagttgg cgttaagttt gacgtgctca gccacatcgt
    13981 tgatggtcag cgcctgatca tagttttcgg caataaagcc cagcatctgg ctgacataaa
    14041 attgcgcatg gcgcgagacg ctgtttttgt gtgtgcgcga ggttttattg accagaatcg
    14101 gttcccagcc agagaggcta aatcgcttga gcatcaggcc aatttcatca atggcgagct
    14161 ggcgaatttg ctcgttcgga ctgtttaatt cctgctgcca gcggcgcact tcaaacgggc
    14221 taagttgctg tgtcgccagt gatttgatca ccataccgtg agtgacgtgg ttaatcaggt
    14281 ctttatccag cggccaggag agaaacagat gcatcggcag attaaaaatc gccatgctct
    14341 gacaggttcc ggtatctgtt agttggtgcg gtgtacaggc ccagaacagc gtgatatgtc
    14401 cctgattgat actcactttt tcattgttga tcaggtattc cacatcgcca tcgaaaggca
    14461 cattcacttc gacctgacca tgccagtggc tggtgggcat gatatgcggt gcgcgaaact
    14521 caatctccat ccgctggtat tccgaataca gcgacagcgg gctgcgggtc tgtttttcgt
    14581 cgctgctgca cataaacgta tctgtattca tggatggctc tctttcctgg aatatcagaa
    14641 ttatggcagg agtgagggag gatgactgcg agtgggagca cggttttcac tctcttccca
    14701 gagaggcgag gggaccatcc gagcattctg aggccgaaaa ctctgctttt cagctaattt
    14761 attcccataa actcagattt actgctgctt cacgcaggat ctgagtttat gggaatgctc
    14821 aacctggaag ccggaggttt tctgcagatt cgcctgccat gatgaagtca ttcaagcaag
    14881 ccaggagatc tgcatgatgt ctgcacccaa aattacattt atcggcgctg gttcgacgat
    14941 tttcgttaaa aatattcttg gtgatgtgtt ccatcgcgag gcgctgaaaa cggcgcatat
    15001 tgccctgatg gacattgatc ccacccgcct ggaagagtcg cacattgtgg tgcgtaagct
    15061 gatggattca gcaggggcca gcggcaaaat cacctgccac acccaacaga aagaagcctt
    15121 acaggatgcc gattttgtgg tggtggcatt tcagattggc ggttatgaac cttgcacggt
    15181 gactgatttc gaggtctgta agcgtcatgg tctggaacaa accattgccg atacgttggg
    15241 gccgggcggt attatgcgcg cgctacgtac cattccgcat ctgtggcaaa tttgcgagga
    15301 catgacggaa gtctgccccg atgccaccat gctcaactac gttaacccaa tggcgatgaa
    15361 tacctgggcg atgtatgccc gctatccgca tatcaaacag gtagggctgt gccattcggt
    15421 gcagggaacg gcggaagagc tggcgcgtga cctcaatatc gacccggcta cgctgcgtta
    15481 ccgttgcgca ggtatcaacc atatggcgtt ttacctggaa ctggagcgca aaaccgccga
    15541 cggcagttac gtgaatctct acccggaact gctggcggct tatgaagcag ggcaggcacc
    15601 gaagccgaat attcatggca atactcgctg ccagaatatt gtgcgctacg aaatgttcaa
    15661 aaagctgggc tacttcgtca cggaatcgtc agaacatttt gctgagtaca caccgtggtt
    15721 tattaagcca ggtcgtgagg atttgattga gcgttataaa gtaccgctgg atgagtaccc
    15781 gaaacgctgc gtcgagcagc tggcgaactg gcataaagag ctggaggagt ataaaaacgc
    15841 ctcccggatt gatattaaac cgtcacggga atatgccagc acaatcatga acgctatctg
    15901 gactggcgag ccgagtgtga tttacggcaa cgtccgtaac gatggattga ttgataacct
    15961 gccacaagga tgttgcgtgg aagtagcctg tctggttgat gctaatggca ttcagccgac
    16021 caaagccggt acgctacctt cgcatctggc cgccctgatg caaaccaaca tcaacgtaca
    16081 gacgctgctg accgaagcta ttcttacgga aaatcgcgac cgtgtttacc acgccgcgat
    16141 gatggacccg catactgccg ccgtgctggg cattgacgaa atatatgctc ttgttgacga
    16201 cctgattgcc gcccacggcg actggctgcc aggctggttg caccgttaag aggttatcgc
    16261 ttccggcgct ctggtgatta agccaaagcg ccgtagctgg cggcaatgaa agcgagcgag
    16321 gaatatcacc gtcgttaatg cgccaagcag cgcgcagaac atatcggatt gcgtgtccca
    16381 ttggtcgccc tgggtgccga gaaaatcatc cgctccctgg cccattgcca gcgctgccca
    16441 ccactcgatt aactcataca tcgcgcttat cgccagcgcc acgcagcaga ccagaaacgc
    16501 caccatctta cgtccgcgaa cgtacatccc gcgaacgaga atttctcgcg ccaccagtgc
    16561 aggcaccagc ccctggaaaa aatgccccag cttgtcatac ggattacggc tcaaccccag
    16621 ccattcctgc acctcaaaac caacggggac tttcgcgtag gtgtattgcc cgccgaccat
    16681 caggatgatg gcgtgaaaga aaatgagcgt atagagcagc ggcgttaacg gataacgttt
    16741 agcggtggca agcagtagcg gcacgacaat aatcaccggt gtcacttcca tcagccaggt
    16801 gagtttgtca ttggccaaaa tgccggtata aatcaggatt aacgttagcg ccagtgcgcc
    16861 ggtgttaaga attaacggct tgagtgtacg gggcatggtg agttcgcaag tcagggaaaa
    16921 tactgactat tgaccagtaa gcgtgaaatt acaatcgcaa aagaggtggc ccagggggat
    16981 cacctggcag catgctgcca ggcgctgggc cgaagaggtt acttagtgca gttcgcgcac
    17041 tgtttgttga cgatttgctg gaagaagtcg ttacctttgt catcgaccag gataaacgcc
    17101 gggaaatctt ctacttcgat tttccagata gcttccatac ccagctccgg ataagcgacg
    17161 cattccagat gcttgatgct ctgctgcgcc agtaccgccg ccggaccgcc gatgctaccg
    17221 aggtaaaagc cgccgtgttt atggcacgcg tcggtaacct gctggctgcg gttgcctttc
    17281 gccagcatga tcatgctgcc gccgtgggat tgcagcagat ccacgtagga gtccatacga
    17341 cctgcggtgg ttgggccaag tgaacctgat ggataaccgg caggcgtttt cgccggaccc
    17401 gcgtagtaga tcgggtgatc tttgatgtac tgcggcagtt ctttaccggc gtcaatcagc
    17461 tctttcagct tggcgtgtgc aatatctcgg cccacgataa tggtgccggt gagcgacaag
    17521 cgggtggata ccgggtattg cgaaagctgg gcgaggatct ctttcatcgg gcggttaagg
    17581 tcaactttca ccgcttcgcc ttcaccggcc ttgcgcagtt cttccggaat gtactggcct
    17641 ggattgtgtt ccagtttttc gatccagata ccttcgcggt tgattttcgc tttaatgtta
    17701 cggtcagcgg agcaggagac gcccatgcct accgggcagg atgcgccgtg acgtggcaga
    17761 cggataacgc ggatgtcgtg cgcgaagtat ttaccgccaa actgcgcgcc aagaccgagt
    17821 ttctgggcct cttccagcag ttcctgttcc agctggatat cgcggaacgc ctgaccatgt
    17881 tcgttccctt ccgtcggcag ttcatcgtaa tagtgagcgc ttgctaactt gacggttttc
    17941 aggttggttt ccgcagacgt accgccaatc acaaacgcga tatggtacgg cgggcaggct
    18001 gcagtaccga gggtacgcat tttctcgacg aggaagtttt tcagtttgcc gggcgtcagc
    18061 agggctttgg tttcctggta gagatacgtt ttgttggcag agccgccgcc tttagcgaca
    18121 cagaggaatt tgtactcatc gccatctacc gcgtacaggt cgatttgcgc aggcaggttc
    18181 gtgccggtgt tgacctcttt atacatgtcc agcggcgcgt tctgtgaata gcgcaggtta
    18241 tcttcgatat aggtgttata gacgcctttc gacagcgctt cttcatcacc gccaccggtc
    18301 cacacgcgct gacctttttt accgacgatg atcgcggtgc cggtatcctg gcaggtcggc
    18361 agcacgcctt tggcggcgat ttcggagttt cttaagaatt gcagcgccac gtacttgtcg
    18421 ttttcgctgg cttctggatc gtgaagaata gccgcaacct gtttctggtg tgccgggcgg
    18481 agcatgaaag aagcatcgtg aaaggcttgc tgcgccagca gagtcagggc ttctggttcc
    18541 actttcagga tggtttcacc gtcgaagtcg gcaacgctaa cgtaatcgga agtgagtaga
    18601 tagtattcgg tattgtcttt ccccatcggg aaaggtgcct ggtagataaa gggtttgttt
    18661 gacatagctt ccagcctgta actctgtatt tgttattcga aaatggcgtg ccgcgtagtc
    18721 acgggcggca cgcaaagtgc atttataaga acccgtacat cgcggcgaag atccagccga
    18781 agacgcacga tacgctcaca ccaatcaacc ccggcagaat aaagctgtgg ttgatgacga
    18841 agcgaccgat gtgggtggtg ccggaacggt caaactgaat cgctgccaga tcgctcggat
    18901 aagtcggcag gatgtaataa ccgtagcaag ccggtgctga agccacgatg tatgccggat
    18961 caacgccgat cgccagcgcg accggaacaa tcgccgccag cgccgcagcc tgagagttta
    19021 caaacttgga aaccagcagc agaacaatgg cataggccca cggatactct ttcaccattt
    19081 cacccagtac gccctgaatt tcagacatat gcgcaccgaa catggtttca gccatccatg
    19141 cgataccgta caccgccacg atggcgatca taccggaacg gaagacttcg ttttttgaga
    19201 tagacgcggg attggttttg gtcaggataa taatcagcgc cccggtcagc agcataaaca
    19261 tctgaataac cagtaccatc gacagcggtt tgccgccgaa ggatggacgc aggtccgaat
    19321 cagcaccaag aagggcgact acagcgattg ccccgaggaa gatccacatt gccagccagt
    19381 tgcttttcgg cagtttttta tcgagcagcg tcgcggtatc accgtaaaca tactcacggt
    19441 tttccggtac ggagatgaat ttctggaact cttcgtcttt atccagatct ttaccgcgga
    19501 accaactgaa gataccgatc gccaggatac cgattaacgt cgatggaatg gtgattgcca
    19561 gcaggtcgag gaactcaaga tggcgaccat caaaggtgac attacccagc atcgcaacca
    19621 aagatacgac cgcaaccgac accggactgg cgataatccc catctgtgca ccaatagaac
    19681 ttgccgccat cggacgttcc ggacggatgt tgttcttaat agcaacgtcg tagatgatcg
    19741 gcagaatggt gtaaaccaca tgacccgtac cgcaaagaat ggtcagcgta caggtcacaa
    19801 acggcgcgac aattgagaca tatttcgggt tgcggcgcag cagcttctcg gcaatttgca
    19861 gcatgacatc aagaccgccc gaagcttgca aggtcgccga tgctgccacc accgcaatga
    19921 taaccagcat gacatcaacc ggtggtttac ctggctgaag gtggaagacg aagaccagaa
    19981 tgaccagacc gataccgcct aataaaccca gcgcgatacc cccctttctg gcaccataaa
    20041 acagacatat cagtattatg ataagttgga tagtaaataa catgtgtgaa ccctcgcgat
    20101 aatcctattt aaatttttgc tgaatagatc acagtcacgt tctgttttgt atgaactgtt
    20161 ttcagagcct gactaaatat ccgtttggtc gttaccggct tgagcaaata cctcacagtg
    20221 aatattggct gattaaagca gcggcaaatt tatgcactgt gataagcggc tttttcagag
    20281 agaaagactc tctggcgatg ggtttatagt ttgtacagcg cagatgttaa tgttttgttt
    20341 gctgttatct tattgatatt tatcggtctg ttttttgttc tcagggcaga tatcattagg
    20401 tttatagatt aatctgatct acccatttgt gggtaaaaat acacataatg tgggtgacat
    20461 aatagttaat taacttttgt tagcgttttg aaattaaaaa caccgttcat ctgaagagat
    20521 attaattttt aacgatgatg gagggataat tatatttgat ctggcacaag ttttactgat
    20581 gaacgatgta acttgtgcca gggatatttt gcattacggt aataattatt acttacagat
    20641 aaccagcgat ccgttattgg caatattgtt tcagcagtga gtagtgttct gcctgaatac
    20701 ggtaacggta aaccggacgc cccgtaacgc cataatggat actggtgaac aagatgtggc
    20761 agttgaccag ccagatgagg tatttacggc aggaaacacg cgagatgtta acctcgttgg
    20821 ccagctcgtc ggttgaaaac tcatagtcct gatgcgcgtc aatccactgg cacagcgtgc
    20881 gtaacgtctg cggcgttaag ccttttggca agcgacgagg atcctgctcg ttggagctgc
    20941 tgccgtggat tagctgatca agctcggcct ggtcataata ctgatgtttt tccagcgcca
    21001 ttttcttttg ccgccagccg gtgagcgcct cttcaaagcg ggaagcctgg aagggtttga
    21061 tcaggtaatc cacaacaccg taatgcagcg aatctttaat ggttgctgca tcggcagcgg
    21121 aggagatgac aatcacatca cttttgcaac gcgcgttatg caggacaggc agtaaatcga
    21181 gcccgttctc tttttgcata tagatatcta gcaatatcag gtcgataggc gtgtcgctgt
    21241 tgaaaataat ctctttggct ttctccagcg tcgaagccgt tccacagcat tgaaagcccg
    21301 ggatttgtgc cacgtatcgg cgattcagct ccgcgaccat tgcgtcgtca tcgataatta
    21361 atacattgat catctgttcg acctctcccc gtcccagggt atctggacaa aaaattgtgt
    21421 gaaaatcccg ggttccgatt ccacggcgat gctgccgccg agattttcta cctgttgttt
    21481 gacaagtgct aaaccgacgc ctcgctcgct tccttttgtc gagacacctt tgtcaaaaat
    21541 gtgatcgatt ttgtcgggtg cgatccccgg tccatcatcg ttaacttcac agtgcagcca
    21601 gccgtgacgg tagtgcaatg ttacgctaat ttcgccaccg ggttccggtc ctaatgcctc
    21661 cagcgcgttt tctatcagat ttcccagcgt ggtaatcagc gtcgtgacct ggtcttcact
    21721 gccgctgtct ggcaactggc tttcactgtt taaaatcagc gtatggccta aatcggtcgc
    21781 gcggttaatc ttactgatta aaaaaccagc tataaccgga gatttgatct tacccagcag
    21841 agagccaatc tcttcctgat agttattggc tgttttgaga atgtaatctt ccaactgctt
    21901 ataactcttc agatgcaata atccgagaat cacgtgcaat ttattcataa attcgtggga
    21961 tcgttcacga agtgcgtcag catagttgac cagaccatcg agtcgctgca tcagtttacg
    22021 tacttcagtt ttgtccctga aggttgaaat ggcaccgatg ataacgccat tactgcgcac
    22081 cggaacggtg ttgatcagta atagccggtc tttaatcgta atctcttcgt cgcgccgcgg
    22141 ggtaccgtcg cgtaacactt ccgagacatc taccacctgt gaccacgagt ggcttagcgt
    22201 cgacagcttc tcatcgtcct gcgacttacg gtaattcagc aattcttgtg cggcatcgtt
    22261 gatcagcgtg acttcaccgc gatcgtccac ggcaacgacg ccttctttga tggactgcaa
    22321 catggcctgg cgttgctcaa acagcgtgga gatttcgtag ggttccaggc cgaaaaggat
    22381 ttttttcagt accttaacca gaatgcaggt gccaatcagc ccgaccagca tgccaaataa
    22441 taccgaccag atgatgctcc agcgactgtc attgatctgt tgggtcacgc gacttaactc
    22501 aaggccgatc gccaccacgc caatttgttt atgattttca tcgtagatgg gggtaaatac
    22561 gcgtaaagcc tgcgccagaa aaccgcgatt gatagcgaca ttttcttcgc cattcagcgc
    22621 tttaaggatg tcatcacctt taaatggctg accaatacgc tgggcttcag gatgcgagta
    22681 gcgaagactt tgcatatcgg taacgacaat aaacagcaga tcgttgcgtt tgcgtacggc
    22741 ttccgcgatg gcctggatgc cgctctcctg cggttttttc tgcaagccct gacggatttc
    22801 cggcgagtcg gcgagggtac gcgccactgc cagtgccttg ttggctagcc cgtctcgcgt
    22861 catatcactg atttgcgaga agtaaatcag atgcaccacc aatagcaccg agaacagtac
    22921 cgcgctgacc attaagatca cagtggtact caatttcatc ggacgtttgc gtaatatgcg
    22981 gtagggcaat gaatgtctca tcagcttcct tgtgtgacaa atttcttaag cattatctct
    23041 gatgaggcgg gtaattcaaa gggagtaaga atgattggct atatagggga agagactctg
    23101 gcaacggaaa ctgccagtgc tgtatgaaga ttccggggct atgcttatag tgaaaaccat
    23161 actgatgaga gagggaaggt catggatcag gcgctactgg acgggggtta tcgctgttat
    23221 accggcgaaa atatcgatgt ctattttaac actgcgatat gtcagcattc tggcaattgc
    23281 gtacgtggca acggcaagtt atttaatctc aaacgaaagc cgtggatcat gccggatgaa
    23341 gtcgacgtca ccactgtggt gaaagtgatt gatatgtgcc caagcggcgc gctgaaatac
    23401 cgtcataaat aagcgagggt aaaatggaaa tacgcgaagg ccacaataaa ttttacatta
    23461 atgacgaaca aggcaagcaa atcgctgaaa ttgtctttgt accgaccgga gagaatttag
    23521 cgattatcga acataccgat gtcgatgaaa gcctgaaagg acaagggatt ggtaaacagc
    23581 tggttgcgaa agtcgtggaa aaaatgcgtc gggaaaaacg aaaaattatc ccactatgcc
    23641 catttgcgaa acacgaattt gataaaacgc gggagtatga tgatattcgc agttgatggg
    23701 agagtacaga gtcacaatat ttttcatgct ctccgcgggg ggatgcagga gagtatctga
    23761 agggtagggg gatgcacaaa gaatggtcag agagagcgtt tttttgtccc aagtcatccc
    23821 ctttactgag caaaaaaaaa agaatatctc ctatatgaga atcatcgatc ggggttaata
    23881 agttttgcgt ccccagagtg ttcaatattg ataggagtca tattatggaa ggtaaaaata
    23941 agttcaatac ttatgttgtt tcttttgatt atccatcatc ttattcctca gtgttcttaa
    24001 ggttaagatc attgatgtat gatatgaatt tctcctctat cgtggctgat gaatatggga
    24061 taccacgaca attgaatgaa aattccttcg caataacgac atcgttagcc gcaagtgaaa
    24121 tcgaagattt aatcaggctt aaatgcttag acttaccgga tattgatttt gacctcaaca
    24181 ttatgaccgt tgatgactat ttccgtcagt tttacaagta gccaggaagg ataagaagaa
    24241 cataaaaaat ggcactattc tctaaaatat taatttttta tgtgattggt gtgaacatat
    24301 cctttgtcat tatctggttt atctcacatg agaaaacaca tattcgttta cttagcgcat
    24361 tcctggtcgg aataacctgg ccaatgagtt tacctgtggc attacttttt tctctctttt
    24421 aggagttgta gttgagtgga cccgctggtt atcttgaaac gaagcgtctc tcctcaaaac
    24481 tggatttgcg gaacgacgaa cgaagcagtc gcctgactgc ttcgttcatt taagtgaaat
    24541 ttatttctgt gggcgcatcg ccgggaagag aataacgtcg cgaatagtat ggctgttagt
    24601 aaacagcata atcattcggt cgataccaat acccagacca gcggttggcg gcagaccata
    24661 ttccagcgca gtcacgtaat cttcgtcata gaacatggct tcgtcgtcac ctgcagcttt
    24721 agcgttaacc tgttcctgga aacgttcagc ctgatcttct gcgtcgttta attcgctaaa
    24781 accattacca atttcacgac caccgatgaa gaattcaaaa cggtcggtga tttccgggtt
    24841 aacatcatta cggcgcgcca gcggggacac ttctgccgga tattccgtaa taaaggttgg
    24901 ctgaatcaga tgtgcttctg ccacttcatc aaagatctct gtgacaatac gtcccagccc
    24961 ccagcttttc tctaccgtaa ttccgataga ttcagctaat gctttagcag catcaaaatt
    25021 atccagatcc gccatatcgg tttctggacg atattttttg attgcttcgc gcatggtgag
    25081 tttttcaaac ggtttgccga aatcaaacac atgctcgcca taagtgactt tagtggcacc
    25141 cagtacctct tgtgccaggg tgcggaacag tgactccgtc agttcaatca aatcatggta
    25201 atccgcatat gccatgtaga gttccatcat tgtgaactca ggattatggc gaacagaaat
    25261 accttcatta cggaagttac ggttgatttc gaatacccgt tcaaaaccgc ctacaaccag
    25321 acgtttcaga tacagctccg gcgcgatacg caggtacata tctaaatcca gagcgttatg
    25381 atgggtaata aacgggcgag cagatgcccc acctggaatt acctgcatca tcggggtttc
    25441 tacttccata aagccgcgcg cgaccatgaa ctgacggata gcggccagaa tttttgaacg
    25501 gacaacaaac gtttgacggg atttatcgtt agcgatgagg tccagataac gttgacgata
    25561 acggacttcc tgatcctgca gaccatggaa tttatctggt aaaggacgta gtgctttagt
    25621 cagcaggcgc agctcagtac agtgaatgga aagctcaccc gtttgcgtct taaacagcgt
    25681 accgcgggca ccgataatgt cacccagatc ccatttttta aactgatcgt tataaacacc
    25741 ttctggcagg ctatctcgtg cgacgtacag ttgaatacgg ccaccgacat cctgcaacgt
    25801 tacaaaggag gctttcccca tgatacgacg ggtcatcatt cggccagcaa ccgagacttc
    25861 aatgtttaag gcttccagtt cctggttatc cttcgcatca aactcttcgt gcaactggtc
    25921 agaggtatgg tcgcggcgaa aatcattggg aaacgccaca ccttgctgac gtagtgccgc
    25981 cagtttttcg cggcgatttc tcagttcatc gttaaaatca atagcctcat tggctccccg
    26041 tgtttctcgt tcagacattt tggttcctct aaatccagct ttcaatttag cgtagataaa
    26101 gagacagatc ggtacactgt attatctgcc tcgactatta ataactcagt ttatcttatc
    26161 gaaactaacg cttacctcaa gttgatatca ctaataaata accataaaaa tggtttaaat
    26221 gacttattaa tctcgatttg ctagtgtgat aaactgaaag ttaatttatt cataaccaat
    26281 tgtttttacg acagttaatc gttgctctcc tgtatcatat tcgtcggcgt gctaaacaga
    26341 aaacgggtag caaaggccaa taccacgatg atcgcgacac aagccaacgt ccactctccc
    26401 atctgagaaa agaatcgctg gtaagctgca attgccatac cgctaatttg cgactctgtc
    26461 gtctgctgtg ccacgacgcc tgccagccag ttggcgaccg cgcctgttgc cagcatataa
    26521 ataccggtta atacgccaga cattttcaga cgcgtgattt gcgcaatcgc caccgggtca
    26581 ataaagagtt cagcaaagcc cattagcgcc agcccggata tcatcacgcc cattgacgct
    26641 tgaccgccag ccgctgcatg tcgggcatca aatgccagca acataaagcc acaagccatc
    26701 agcagtaagc caaaggcaaa cttcagccag acgcgcaatg ctgaattgcc gcggctttct
    26761 ggcgacgcca gccaggccag aacaacccca gcgagcatca ctgcaatcgc attcactgac
    26821 tggaatagcg cagtcggcac ttcaatattg aatgcctgac gattcacaaa gcgatcgata
    26881 aacaagctga tggtgctgcc gccctgttgt gccagtaccc agaacaacgt tccgacaagc
    26941 atcaacaata caatttgcca aagagcacgg cggtgttcgg ggtatttgat catcatgcgg
    27001 gcaatgattt gtgcggcaat gaggcaaacg atcgccagca aatatcccga ccagtcgttc
    27061 tccagcagca gggtaaaaaa tactggggct aaacagagca tcaccactaa ccagctccat
    27121 actggtaagg caaatttcac gctagtgagc gctttcttat ccatactacg cgtggactgg
    27181 aaatgacgat gaccgcttaa gaaaatcaac aaaccgataa acatgccgcc acccgcaagg
    27241 gcaaagccaa catgccaccc ataccactga gcagccaggc cgcaggcgat gggcgcggcg
    27301 atagaaccga tattgcccgc agcatacagc agcgaaaaac cgccatcacg tcgatgatcg
    27361 ttctcgtcgt agagctcgcc aagcaaacag ctgatgtttg atttgaataa accgtagcca
    27421 caaataatga ttgccagcgc cagatacagg ctaaaggttg aatttgtatc aatgcccagc
    27481 accacatggc caagggtcat taacagcgcg ccggcaatca ctgcagtgcg gttgccgagc
    27541 aggcggtcgg caagccagcc gccgagaata ggggtaacgt ataccagaga agcatatgcg
    27601 ctgaacaggc tgatggcatg gttatcatca aaaccaagct gatgggtgag atagagaatg
    27661 agtaaggcac gcatgccgta aaaactgaag tactcccaga tttggatcgc cacgatatag
    27721 tatatcgcgc gcggctgtga gggtgttttc atgtgttctc cttatgagca aaaaagggaa
    27781 gtggcaagcc acttcccttg tacgagctaa ttattttttg ctttcttctt tcaatacctt
    27841 aacggtatag cggccatcag cctgacggta tgcaccgtga atatcggttt caaagcccgg
    27901 atagtgagcg ccgatttcac acagcatctg caggaactcc agaaccggac ggctttcttc
    27961 ggtgatcatt tcacccggca ttaccagagg aactcccggc ggatatggaa ggatcatatt
    28021 ggcattaata cgaccgacca tttcgtcgag gtaaacttct tcggtcatac cgtgcagctc
    28081 tttctggaac gcagcatacg gagtcattac catcgtcggc agcacttcaa atgcgcgata
    28141 catcagatcc ggcagattgt ggtgaacaat cagtttgtgg atattctgag ccagttcctg
    28201 aatacgcatg ttttcataga attcaggatc ttcacgatac agagacggca gcatgttttt
    28261 cacacgcagg ttcagatcga acgcacgttt gaagtcagtc agagcacgca gcaggctcag
    28321 tgctttggtc ttatcgatac cgatgctgaa caggaacagc aggttatacg gaccggtttt
    28381 ctcaacaacg atgccatgtt cgtcgaggta tttcgccacg atgctggccg gaataccgaa
    28441 gtcgctcatg gtgccgtctt tttccatccc cggagtcagc agggtgactt tgatcgggtc
    28501 aagatacatg tgctcgttat cgatgttttt gaagccgtgc caggtgctgt cagaacgcag
    28561 cggccagcat tcagtggtat cgatatgatc cggctgccat acatcaaaga accagccatc
    28621 agattccgtt ctcagacgtt tgatctcttt acggaatttg atcgcacgtt caatggaacc
    28681 gttgatcaga cgtttacctg cattgccttt catcatcgcc gctgcggttt cagtggacgc
    28741 cacgataccg tagtgcggag aagtggtggt gtgcatcatg taggcttcgt taaaggtttc
    28801 ttcgtttacg tcacctttaa cgtggatcat ggaagcctga gagaatgccg ccagcagttt
    28861 gtgagtggac tgggtttcgt aaatcacttt cccttctaca cggccaccgc tcataccgca
    28921 tttaccttcg taaatcggtg agaagttggt gtaaggcacc cacgcggagt caaagtggat
    28981 ggattttaca tccagtgttt tcttgatgaa gtcggtgttg tacagcagac catcataggt
    29041 agagttggta attacagcat gtaccggcca ggttgcgttt ggtgtttctt tcacgcgctt
    29101 agcaatggta gcgtgctgga attcactctg tgggatacca ccaagaatac cgtaagcgtt
    29161 acgggtcggg cggaaataga ttggcgtaac atcgctcatc atcatcaggt gggtcagcga
    29221 tttgtggcag ttacggtcaa tcagaatggt gctgcctgcc ggagcagagt acataccaac
    29281 aattttgttc gcagtggaag taccgttggt caccatgtag ctgcggtctg cgttaaagac
    29341 gcgagcgata tactgttctg cttctttgtg tggaccactg tgatccagca gagaacccag
    29401 ttcagatact gaaatggaaa tatcagattt catggtgttc ggaccaaaga aatcatagaa
    29461 caggctacct accgggcttt tctggaatgc agtaccgccc atatgaccag gagtacagaa
    29521 agtatattta ccttcacgaa catatttaaa cagtgcttta gtcagcggag gcagaatagt
    29581 gttgatatat tcgtcagtgg tctgcttgat cttgttagca atatcatcag cagcacccag
    29641 cgcatattca aagaagctaa tctgtaaacg cagatcgttc aggcttacat cgagagtgga
    29701 atacgtatta gcgaacgcgt acaacggcag gttctcgttc attttgctaa tttcttcgca
    29761 cagctcgaga ttatatttat cccagtcaaa aataacgccg cacagacgcg cattgttttc
    29821 gatcagtttt aataagtcgt cacggtcgtt cgggtaaaca atctggaagt tcagacgttc
    29881 aagcgcgcga tgaagttcac ggatgggttc ttctttaaaa taaaccccca tgtgattcaa
    29941 tattgcaata acgttcatag tcatatctcc aggtaaaaaa ggcccctccc aacacatggg
    30001 acaaaatgaa aggaggagcc tcggaaaata cttttaatta atgtgcgtta gacgctgtgt
    30061 ggttatccat tgagtggctc tggcgctcgt gcattttgcg agcgtagaac atcaggataa
    30121 tcaggctgac gatgaaggta cctgccagct cgaaggagct tgcgcccatc agcgcgatga
    30181 agcagaacac gcaacccagt acagagcaga tcagactgac aaagttgcgg atgttaacgc
    30241 cttcaaaacg aatcaggtca acgcaagagt agaagtacgg cagcatagtc agcagtactg
    30301 cgataccggt cagttcaccg aacaggtcag aggctttacc accggcagag ttcatcagag
    30361 tgatgaggat catcagggca gtcattttca ctgcagccag cagcagacct tttttcggaa
    30421 taccgttgct gtcgacttca ccataaactt tcgggaagtt accgtcgtta gcggcacgta
    30481 cacctgcctg gcctaccaac atcatccagg agcccagaga agtcaggcac gcaaaggcgg
    30541 tgaatgcaga aaccagcggc gcagcccagt taccgaggat agttgaagca ctgattgcaa
    30601 acggagcacc ggaagccgcc attacagaag acggatacat accggaaagc acctgagtcg
    30661 cagcgatata aacaatacct gctaaaccag tacccagcat ggttgccagc ggaacggtac
    30721 gtttcgggtt tttaaccata ccagtactta cagctgcgga ttcaacaccc acgaaggccc
    30781 acaggcagag cagaatactt ttaatgatcg catgaccatc ggtggtatcc gcagtattcc
    30841 agttagcagc ataagtcgca gcatcaaacc aatgccagcc aacaatagct gtcattacca
    30901 caggaataag aaccagcacc agaccaatag tggttaaacg gcttacccag gtaccgccga
    30961 gcatatttac aaaggtaaat acccagacga tagcaataca ggcgataccc gccggaacag
    31021 gatcatttaa tactgggaag aaggtggaaa gataagatac agcggtaata ccaatcgcca
    31081 ggttaccaat ccagttagca tggtaataaa gaacacctgt ctgaaaacca aatgcagggg
    31141 aaatttctcc ggcataagca attgggccac cttgttgcgg gttttttgtt gccagtcggg
    31201 catatacata cgccagcgac attgcaccaa taatagagat aatccaaccc cagatagcaa
    31261 taccaccgat acttgctagg ttcgcaggta ataatgcaat accgctcccc atcatattac
    31321 cggcaacaac accggtacag gcaaatagcc cgatcttctt ggcagaactc atgctcttct
    31381 cctaatttca tttttgaatt tggagtccgg gtcatgatgt ataactattt cctgaccaga
    31441 ccaaactggc gctaagaata ctcacgaaaa aaggattagt cctaaagatt aggtgaaata
    31501 acacaaaagt ttctgtaagt gagaacttga ggttttttat taacacatca ggatcgcaag
    31561 ttgatatcat gaaaagataa acattcaatg tttacaatgg attgcgggac attttctggt
    31621 taaatttatg taataaaaat tatgcggcaa ataaattacc gcaacatatt ataccaacag
    31681 aaacatacaa aaactcaaca ataaatattc ccgagtatga atcaacctgg gagtcactta
    31741 ttctgaagcg agaaatttgt cgagataagg tacaacataa ggaacagaag tctggaatat
    31801 accattttca atccagtaaa gggtgtttgc ccctgggcgt aaattaaagg cggtgagata
    31861 tgcatcagct gcttcccggt tcatcccctt catttcataa accttgccaa gcaacacata
    31921 atttagccag gacatttcaa gatcaatgcc agtatttatc gcctggtaag actcatctgt
    31981 tttacctttt accagagcac tgaccgcttt tatttgatat ataatggaca ggttattcaa
    32041 ttccggcagt gtaacaatgt tatctatttc tgtattcagt gctgctaatt gtttttcatc
    32101 taaaggatgt tgagaatggc gcacgatatc aactaatgct ttttctgctc tcgcgtaggt
    32161 aaattctggg gatgattgaa caatctcacc taataattca ctggcacgat tcaatgattt
    32221 atcatcgcca tgcagtaaat aatcatgagc ctgataaaaa ttagttaata acgcaccacg
    32281 atgcggcaaa atttgctgga gcgtctcctg cattcgttgt ggccacggtt ggtttaacgc
    32341 ttttgataaa ctctccagta aatcattttg aatcgccagc tgattaccgt tagtgatgac
    32401 ataacgttta tccagcatgg ttgaaccatc tgcattgtct accaatttta ccgacataaa
    32461 gcattgttga gcacggtatt ggcgctgatt aacaaacgca atagataatg ttttaccgga
    32521 actgctcggt tcatcaatgt tgtagttgat tttgtcatgc accataaagg tggagaaggt
    32581 gttaagtgat gtcgccacca aatcacccac gcctatcgcg taagagagct gatacgggga
    32641 actccagctg ttacaactct tattaaccat attaatgtca atatcgcgtg gattgagcaa
    32701 aatgcgcgat ttactcatcg gaagacgtgt ttcaagactt gaaaatgcta ccagtgcgac
    32761 acagatacct aacgacaaca ggaaaaaaaa ccatacccaa aaggtagtga atcgtttgct
    32821 tttaactggg gattgttcag gtggcgtagc ggtgttttga atgttaagac tgtgggaggg
    32881 agaatctgtg gcaggaaccg cctctggtat agggggaggc gaagatagca ttatttcctc
    32941 tccctcttct tcgctgtacc agataaccgg caccattaat ttatagccgc gctttggtac
    33001 agtagcgata tagacaggac tatcttcatc attatctttt aatgacttac gtagttctga
    33061 gatactctgc gtcacaacgt gattggtgac aatacttctc ttccagacat tatcgataag
    33121 ttcatccctg ctaagtactt cgccactgtg ttgagcaaag aaaaccagaa gatcgattaa
    33181 tctcggctca agggtaagtt gacgcccatt gcggctaatt tggtttatgg acggagtaac
    33241 aagccattcg ccaacgcgaa ctacaggttg ttgcataata gaaactcatt cgaaaaggga
    33301 atgatgcaat gataattgcc ataacctatt ttttccatct atagatgggt ttatttacat
    33361 attattggtg aatgcaagac gttattttta cccgccataa acttcttgat tacatagtat
    33421 tacgaaagga ttttactgag aaccagaagt aattttcctt accatcaaaa ttcatcatct
    33481 ttgccaaaga aaaatgttca gaaaataatc catgaaaaat tgtccggagc gcttactatt
    33541 ttaatggatt gttagtcttt gcatgagcaa gtggaccgat acatttctct ttgttctcat
    33601 tcagaaaatc ttatcagtcg gcgttcagac cgatgttgtg ctttatggat gcgttacgct
    33661 cctgatgacg tcatttgacg ttcaacagca tcacggggcc gcacgacatt tcacgtcagt
    33721 cagtgctata gctcagaaac aaattttccc gaattgggat atgcccgcaa attgctggtg
    33781 atgtggggag aatctggttg agttcggtag aattgatttg gaggcagaac gcttaaatcg
    33841 tggcgtcctg aaacgaaaaa cggacctccg tggaggtccg tttatatgaa tttggtgccg
    33901 gactcggaat cgaaaatttc ttttatcata ttgatattaa tctgatttgt ttggtttgat
    33961 taaaaatgta ccctcaatta tacccgcagt cccttttgat atcgaaaggg aatcacactc
    34021 gggatcaggc tgagagcaca gaaggaaagt gcctgactat tatatcgtta attctgtcaa
    34081 tcagttccag ccttttgaaa gtgatgtgtg cagatccctt cttaaagtat ttaatgataa
    34141 acatttcgtc ttcatagtac tctttaccct gaacagaccg gatatgctca tccagacgaa
    34201 ttatgatatt ttcccggttg tcgggagtgg ggatgccact gaagagatgc agcatccttt
    34261 ccaggtcggc aacccggtca gtctgtggtc cggtgataag atgaaatccc caccggcccc
    34321 atctcaccag attgttgacg ataattttac tgccaaattt acagggagag ttggttttat
    34381 aattccagct cagtcccctg aagacgttaa tcactccccg ctcaaacacc tcatccttat
    34441 tctggtgcag ttgttcaaat gtgctcataa tgttcgcttc actgatttcc ggaaaattat
    34501 cgtactccag tgaccggtac catgtatcac gggtctgcgc atccattaat gacagcatcc
    34561 cggagcgttg catcaggtca cgccagattt cacggtcaag gttgcgggta atggctttca
    34621 ttgccgtttc aggtttctcc atgagccagc agccgcagcg aaaatcctgt ttcatggccc
    34681 agtccagtgc ggttttaccg ccaatacttt ctgtcattgc tgagatttca gccagttgcc
    34741 ggataagtat gtcgatttgc aacagtgtac tctttcgtac agccagaatg tggctgactg
    34801 aggttgagca gataacgtcc gtatgtccgt tgaccacttc cggacgggag actgtgattt
    34861 cagacataat cgtttttcct ttttgcagat aaatgaaaac gccagccctg ttcaggctgg
    34921 cgtcagtgga atgaagtatg gtgagtaata tttaccggtt ctggtgcaga agctgcagtt
    34981 ggcgcagggt atggatatct tccctggcct gttcaatgca gggcaacagt gctgccgaat
    35041 ccgttttatc ctcatcgttg tcgaagataa tccccgattc gcagtcgata ttgtcctgca
    35101 gccacacaat cagaatatcc agcgccgttt ctgtggctaa tggcattacg ctctgtatca
    35161 ctgtattgtc ttccggcaac tgatgagggc tggcagaggt cgccggtgtt tcggtagtga
    35221 cacgctcatc caccacgcgg agtgaataac cattttccgc gactttatta aacagttcag
    35281 cgagattaac accatcgacg tcaacgacaa tgcgccccat gttcagtgcc tgcacgttaa
    35341 tgctgtcggc ttccagcgtc agggccagtt tcattgtttc gcctccggat gcttcccccg
    35401 ggtaatgtta tttaccgttc tgtagttgct gcgggtcatc agacctgttg cccggcgtgc
    35461 ccggagaata tcaatgctgt tgattaactg cgacgaagtt cctgcgctga atcccggctg
    35521 gtcggttcgt accagtgcgt atttttccac gagaaagttc accgcatcac acagtgcaat
    35581 acctgcctca atatgctgct caatcacacg ttcatcggcg aacggtgtgt catttaacgt
    35641 gaggccgtag tgctggtcca gcag
//
LOCUS       DADXDL010000051        34857 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.051, whole genome shotgun sequence.
ACCESSION   DADXDL010000051 DADXDL010000000
VERSION     DADXDL010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34857)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34857)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34857
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.051"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..86
                     /locus_tag="IRB70_002750"
     CDS             <1..86
                     /locus_tag="IRB70_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HBC0632644.1"
                     /translation="RKSLSFSKSVELHDKVIGHYLNIKHYQ"
     gene            complement(334..409)
                     /locus_tag="IRB70_002751"
     tRNA            complement(334..409)
                     /locus_tag="IRB70_002751"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(374..376),aa:Asn,seq:gtt)
     gene            complement(510..1307)
                     /gene="mtfA"
                     /locus_tag="IRB70_002752"
     CDS             complement(510..1307)
                     /gene="mtfA"
                     /locus_tag="IRB70_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310801.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DgsA anti-repressor MtfA"
                     /protein_id="HBC0632645.1"
                     /translation="MIKWPWKVQESAHQTALPWQEALSIPLLTCLTEQEQSKLVTLAE
                     RFLQQKRLVPLQGFELDSLRSCRIALLFCLPVLELGLEWLDGFHEVLIYPAPFVVDDE
                     WEDDIGLVHNQRIVQSGQSWQQGPIVLNWLDIQDSFDASGFNLIIHEVAHKLDTRNGD
                     RASGVPFIPLREVAGWEHDLHAAMNNIQEEIELVGENAASIDAYAASDPAECFAVLSE
                     YFFSAPELFAPRFPSLWQRFCQFYQQDPLQRLRHANDTDSFSATNVH"
     gene            1401..1490
                     /locus_tag="IRB70_002753"
     tRNA            1401..1490
                     /locus_tag="IRB70_002753"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1435..1437,aa:Ser,seq:cga)
     gene            complement(2060..2590)
                     /locus_tag="IRB70_002754"
     CDS             complement(2060..2590)
                     /locus_tag="IRB70_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416483.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome b"
                     /protein_id="HBC0632646.1"
                     /translation="MNRFSKTQIYLHWITLLFIAITYAAMELRGWFPKGSNTYLLMRE
                     THYNAGIFVWVLMFLRLIIKHRYSDPSIVPPPPAWQMKAASLMHIMLYITFLALPLLG
                     IALMAYSGKSWSFLGFNVPPFVTPNSEIKALIKNIHETWANIGYFLIAAHAGAALFHH
                     YIQKDNTLLRMMPRHK"
     gene            complement(2935..3585)
                     /gene="zinT"
                     /locus_tag="IRB70_002755"
     CDS             complement(2935..3585)
                     /gene="zinT"
                     /locus_tag="IRB70_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-binding protein ZinT"
                     /protein_id="HBC0632647.1"
                     /translation="MAIRLHKLAVALGVFIVSAPAFSHGHHSHGKPLTEVEQKAANGV
                     FDDANVQNRTLSDWDGVWQSVYPLLQSGKLDPVFQKKADADKTKTFAEIKDYYHKGYA
                     TDIEMIGIEDGIVEFHRNNETTSCKYDYDGYKILTYKSGKKGVRYLFECKDPESKAPK
                     YIQFSDHIIAPRKSSHFHIFMGNDSQQSLLNEMENWPTYYPYQLSSEEVVEEMMSH"
     gene            complement(3842..4477)
                     /gene="msrQ"
                     /locus_tag="IRB70_002756"
     CDS             complement(3842..4477)
                     /gene="msrQ"
                     /locus_tag="IRB70_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase
                     heme-binding subunit MsrQ"
                     /protein_id="HBC0632648.1"
                     /translation="MRLTAKQVTWLKVSLHLAGLLPFLWLVWAINHGGLGADPVKDIQ
                     HFTGRTALKFLLATLLITPLARYAKQPLLIRTRRLLGLWCFAWATLHLTSYALLELGV
                     NNLALLGKELITRPYLTLGIISWVILLALAFTSTQAMQRKLGKHWQQLHNFVYLVAIL
                     APIHYLWSVKIISPQPLIYAGLAVLLLALRYKKLRSLFNRLRKQVHNKLSV"
     gene            complement(4478..5482)
                     /gene="msrP"
                     /locus_tag="IRB70_002757"
     CDS             complement(4478..5482)
                     /gene="msrP"
                     /locus_tag="IRB70_002757"
                     /EC_number="1.8.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-methionine-sulfoxide reductase catalytic
                     subunit MsrP"
                     /protein_id="HBC0632649.1"
                     /translation="MKKNQFLKESDVTAESVFFMKRRQVLKALGISAAALSLPHAAHA
                     DLLSWFKGNDRPPAPAGKPLEFSKPAAWQNNLPLTPADKVSGYNNFYEFGLDKADPAA
                     NAGSLKTDPWTLKISGEVAKPLTLDHDDLTRRFPLEERIYRMRCVEAWSMVVPWIGFP
                     LHKLLALAEPTSNAKYVAFETIYAPEQMPGQQDRFIGGGLKYPYVEGLRLDEAMHPLT
                     LMTVGVYGKALPPQNGAPVRLIVPWKYGFKGIKSIVSIKLTRERPPTTWNLAAPDEYG
                     FYANVNPHVDHPRWSQATERFIGSGGILDVQRQPTLLFNGYADQVASLYRGLDLRENF
                     "
     gene            complement(5591..6004)
                     /gene="hiuH"
                     /locus_tag="IRB70_002758"
     CDS             complement(5591..6004)
                     /gene="hiuH"
                     /locus_tag="IRB70_002758"
                     /EC_number="3.5.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyisourate hydrolase"
                     /protein_id="HBC0632650.1"
                     /translation="MLKRYLVLSVATAAFSLPSLVYAAQQNILSVHILNQQTGKPAAD
                     VTVTLEKKADNGWLQLNTAKTDKDGRIKALWPEQTATTGDYRVVFKTGDYFKKQNLES
                     FFPEIPVEFHINKVNEHYHVPLLLSQYGYSTYRGS"
     gene            6137..6808
                     /gene="hprR"
                     /locus_tag="IRB70_002759"
     CDS             6137..6808
                     /gene="hprR"
                     /locus_tag="IRB70_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707854.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor HprR"
                     /protein_id="HBC0632651.1"
                     /translation="MKILLIEDNQRTQEWVTQGLSEAGYVIDAVSDGRDGLYLALKDD
                     YALIILDIMLPGMDGWQILQTLRTAKQTPVICLTARDSVDDRVRGLDSGANDYLVKPF
                     SFSELLARVRAQLRQHHALNSTLEISGLRMDSVSQSVSRDNISITLTRKEFQLLWLLA
                     SRAGEIIPRTVIASEIWGINFDSDTNTVDVAIRRLRAKVDDPFPEKLIATIRGMGYSF
                     VAVKK"
     gene            6808..8166
                     /gene="hprS"
                     /locus_tag="IRB70_002760"
     CDS             6808..8166
                     /gene="hprS"
                     /locus_tag="IRB70_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     HprS"
                     /protein_id="HBC0632652.1"
                     /translation="MKRLSITVRLTLLFILLLSVAGAGIVWTLYNGLASELKWRDDTT
                     LINRTAQIKQLLIDGVNPDTLPVYFNRMMDVSQDILIIHGDGINKIVNRTNVSDDMLN
                     NIPASETISAAGIYRSIINDTEIDALRINIDEVSPSLTVTVAKLASARHNMLEQYKIN
                     SIIICIVAIVLCSVLSPLLIRTGLREIKKLSGVTEALNYNDSREPVEVSALPRELKPL
                     GQALNKMHQALVKDFERLSQFADDLAHELRTPINALLGQNQVTLSQTRSIAEYQKTIA
                     GNIEELENISRLTENILFLARADKNNVLVKLDSLSLNKEVENLLDYLEYLSDEKEICF
                     KVECNQQIFADKILLQRMLSNLIVNAIRYSPEKSRIHITSFLDTNGYLNIDVASPGTK
                     IHEPEKLFRRFWRGDNSRHSVGQGLGLSLVKAIAELHGGSATYHYLNKHNVFRIMLPQ
                     RN"
     gene            complement(8274..9125)
                     /gene="hchA"
                     /locus_tag="IRB70_002761"
     CDS             complement(8274..9125)
                     /gene="hchA"
                     /locus_tag="IRB70_002761"
                     /EC_number="3.5.1.124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein deglycase HchA"
                     /protein_id="HBC0632653.1"
                     /translation="MTVQTSKNPQVDIAEDNAFFPSEYSLSQYTSPVSDLDGVDYPKP
                     YRGKHKILVIAADERYLPTDNGKLFSTGNHPIETLLPLYHLHAAGFEFEVATISGLMT
                     KFEYWAMPHKDEKVMPFFEQHKSLFRNPKKLADVVASLNADSEYAAIFVPGGHGALIG
                     LPESQDVAAALQWAIKNDRFVISLCHGPAAFLALRHGDNPLNGYSICAFPDAADKQTP
                     EIGYMPGHLTWYFGEELKKMGMNIINDDITGRVHKDRKVLTGDSPFAANALGKLAAQE
                     MLAAYAG"
     gene            9381..9576
                     /locus_tag="IRB70_002762"
                     /pseudo
     CDS             9381..9576
                     /locus_tag="IRB70_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353128.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9716..10930)
                     /gene="ompC"
                     /locus_tag="IRB70_002763"
     CDS             complement(9716..10930)
                     /gene="ompC"
                     /locus_tag="IRB70_002763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001080680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HBC0632654.1"
                     /translation="MKRKVLAMLVPALLVAGAANAAEVYNKDGNKLDLYGKVAGLHYF
                     SDDAGSDGDKSYARIGFKGETQIADQFTGYGQWEYNLQANGTEGDGDNSATRLAFAGL
                     GFGQNGTFDYGRNYGVVYDIEAWTDMLPEFGGDTYAGADNFMNGRTNGVATYRNNGFF
                     GQVDGLNFALQYQSNNESGSDGLFGQEGSGSGDGRSLAKENGDGFGMSTSYDFDFGLS
                     LGAAYSNSDRSNNQAARGYGDGNHFYGNSYAGGGTAEAWTVGAKYDANNVYLAAMYAE
                     TRNMTAYGSSDSHSADGKLGGGGIANKTQNFEVVAQYQFDFGLRPSIAYLQSKGKDLG
                     GQEMYNNGNYHYTNKDLVKYVEVGAIYYFNKNMSTYVDYKINLLDNDDDFYANNGIAT
                     DDIVAVGLVYQF"
     gene            11496..11861
                     /locus_tag="IRB70_002764"
     CDS             11496..11861
                     /locus_tag="IRB70_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBC0632655.1"
                     /translation="MEKCDFYHIIVLSLSFPGYLKMEYGSTKMEERLSRSPGGKLALW
                     AFYTWCGYFVWAMARYIWVMSRIPDAPVSGFESDLGSTAGKWLGALVGFLFMALVGAL
                     LGSIAWYTRPRPARSRRYE"
     gene            11901..12596
                     /locus_tag="IRB70_002765"
     CDS             11901..12596
                     /locus_tag="IRB70_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBC0632656.1"
                     /translation="MDLQHWQAQFENWLKNHHQHQDAAHDVCHFRRVWATAQKLAADD
                     DVDMLVILTACYFHDIVSLAKNHPQRQRSSILAAEETRRLLREEFEQFPAEKIEAVCH
                     AIAAHSFSAQIAPLTTEAKIVQDADRLEALGAIGLARVFAVSGALGVALFDGEDPFAQ
                     HRPLDDKRYALDHFQTKLLKLPQTMQTARGKQLAQHNAHFLVEFMAKLSAELAGENEG
                     VDHKVIDAFSSAG"
     gene            12663..14081
                     /gene="dcm"
                     /locus_tag="IRB70_002766"
     CDS             12663..14081
                     /gene="dcm"
                     /locus_tag="IRB70_002766"
                     /EC_number="2.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-cytosine methyltransferase"
                     /protein_id="HBC0632657.1"
                     /translation="MQENISVTDSYSTGNAAQAMLEKLLQIYDVKTLVAQLNGVGENH
                     WSAAILKRALANDSAWHRLSEKEFAHLQTLLPKPPAHHPHYAFRFIDLFAGIGGIRRG
                     FESIGGQCVFTSEWNKHAVRTYKANHYCDPATHHFNEDIRDITLSHKEGVSDEAAAEH
                     IRQHIPEHDVLLAGFPCQPFSLAGVSKKNSLGRAHGFACDTQGTLFFDVVRIIDARRP
                     AMFVLENVKNLKSHDQGKTFRIIMQTLDELGYDVADAEDNGPDDPKIIDGKHFLPQHR
                     ERIVLVGFRRDLNLKADFTLRDISECFPAQRVTLAQLLDPMVEAKYILTPVLWKYLYR
                     YAKKHQARGNGFGYGMVYPNNPQSVTRTLSARYYKDGAEILIDRGWDMAKGEKDFDDP
                     QNQQHRPRRLTPRECARLMGFEAPGEAKFRIPVSDTQAYRQFGNSVVVPVFAAVAKLL
                     EPKIKQAVALRQQEAQHGRRSR"
     gene            14062..14532
                     /gene="vsr"
                     /locus_tag="IRB70_002767"
     CDS             14062..14532
                     /gene="vsr"
                     /locus_tag="IRB70_002767"
                     /EC_number="3.1.-.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VSPR family DNA mismatch endonuclease"
                     /protein_id="HBC0632658.1"
                     /translation="MADVHDKATRSKNMRAIATRDTAIEKRLASLLTGQGLAFRVQDA
                     SLPGRPDFVVDEYRCVIFTHGCFWHHHHCYLFKVPATRTEFWLEKISKNVERDRRDIS
                     RLQELGWRVLIVWECALRGREKLTDEALTERLEEWICGEGASAQIDTQGIHLLA"
     gene            complement(14521..15441)
                     /gene="yedA"
                     /locus_tag="IRB70_002768"
     CDS             complement(14521..15441)
                     /gene="yedA"
                     /locus_tag="IRB70_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="drug/metabolite exporter YedA"
                     /protein_id="HBC0632659.1"
                     /translation="MRFRQLLPLFGALFALYIIWGSTYFVIRIGVESWPPLMMAGVRF
                     LAAGILLLAFLLLRGHKLPPLRPLLNAALIGLLLLAVGNGMVTVAEHQNVPSGIAAVV
                     VATVPLFTLCFSRLFGIKTRKLEWVGIAIGLAGIIMLNSGGNLSGNPWGAILILIGSI
                     SWAFGSVYGSRITLPVGMMAGAIEMLAAGVVLMIASMIAGEKLTALPSLSGFLAVGYL
                     ALFGSIIAINAYMYLIRNVSPALATSYAYVNPVVAVLLGTGLGGETLSKIEWLALGVI
                     VFAVVLVTLGKYLFPAKPVVAPVIQDASSE"
     gene            15614..16531
                     /locus_tag="IRB70_002769"
     CDS             15614..16531
                     /locus_tag="IRB70_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF808 domain-containing protein"
                     /protein_id="HBC0632660.1"
                     /translation="MLLAGSSLLTLLDDIATLLDDISVMGKLAAKKTAGVLGDDLSLN
                     AQQVSGVRANRELPVVWGVAKGSLINKVILVPLALIISAFIPWAITPLLMIGGAFLCF
                     EGVEKVLHMLEARKHKEDPAQSQQRLEKLAAQDPLKFEKDKIKGAIRTDFILSAEIVA
                     ITLGIVAEAPLLNQVLVLSGIALVVTVGVYGLVGVIVKIDDLGYWLAEKSSALMQALG
                     KGLLIIAPWLMKALSIVGTLAMFLVGGGIVVHGIAPLHHAIEHFAGQQSAVVAMILPT
                     VLNLILGFIIGGIVVLGVKAVAKIRGQAH"
     gene            16610..16792
                     /locus_tag="IRB70_002770"
     CDS             16610..16792
                     /locus_tag="IRB70_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2158 domain-containing protein"
                     /protein_id="HBC0632661.1"
                     /translation="MSFMVSEEVTVKEGGPRMIVTGYSSGMVECRWYDGYGVKREAFH
                     ETELVPGEGSRSAEEV"
     gene            17030..18724
                     /gene="yedQ"
                     /locus_tag="IRB70_002771"
                     /pseudo
     CDS             17030..18724
                     /gene="yedQ"
                     /locus_tag="IRB70_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310721.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis regulator YedQ"
     gene            complement(18721..19536)
                     /locus_tag="IRB70_002772"
     CDS             complement(18721..19536)
                     /locus_tag="IRB70_002772"
                     /EC_number="3.1.3.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-3-phosphoglycerate phosphatase-related
                     protein"
                     /protein_id="HBC0632662.1"
                     /translation="MFSIQQPLLVFSDLDGTLLDSHSYDWQPAAPWLTRLREANVPVI
                     LCSSKTSAEMLYLQKMLGLQGLPLIAENGAVIQLAEQWQEIDGFPRIISGISHGEISQ
                     VLNTLREKEHFKFTTFDDVDDATIAEWTGLSRSQAALTQLHEASVTLIWRDSDERMAQ
                     FTARLNELGLQFMQGARFWHVLDASAGKDQAANWIIATYQQLSGKRPTTLGLGDGPND
                     APLLEVMDYAVIVKGLNREGVHLHDEDPARVWRTQREGPEGWREGLDHFFSAR"
     gene            complement(19834..20061)
                     /gene="yodD"
                     /locus_tag="IRB70_002773"
     CDS             complement(19834..20061)
                     /gene="yodD"
                     /locus_tag="IRB70_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416463.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide/acid resistance protein YodD"
                     /protein_id="HBC0632663.1"
                     /translation="MKTAKEYSDTAKREVSVDVDALLAAINEISESEVHRSQNDSEHV
                     SVDGREYHTWRELADAFELDIHDFSVSEVNR"
     gene            20224..20412
                     /gene="dsrB"
                     /locus_tag="IRB70_002774"
     CDS             20224..20412
                     /gene="dsrB"
                     /locus_tag="IRB70_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein DsrB"
                     /protein_id="HBC0632664.1"
                     /translation="MKVNDRVTVKTDGGPRRPGVVLAVEEFSEGTMYLVSLEDYPLGI
                     WFFNEAGHQDGIFVEKAE"
     gene            complement(20456..21070)
                     /gene="rcsA"
                     /locus_tag="IRB70_002775"
     CDS             complement(20456..21070)
                     /gene="rcsA"
                     /locus_tag="IRB70_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsA"
                     /protein_id="HBC0632665.1"
                     /translation="MSTIIMDLCSYTRLGLTGYLLSRGVKKREINDIETVDDLAIACD
                     SQRPSVVFINEDCFIHDASNSQHIINQHPNTLFIVFMAIANVHFDEYLLVRKNLLISS
                     KSIKPESLDDILGDILKKETTITSFLNMPTLSLSRTESSMLRMWMAGQGTIQISDQMN
                     IKAKTVSSHKGNIKRKIKTHNKQVIYHVVRLTDNVTNGIFVNMR"
     gene            complement(21360..22145)
                     /gene="fliR"
                     /locus_tag="IRB70_002776"
     CDS             complement(21360..22145)
                     /gene="fliR"
                     /locus_tag="IRB70_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliR"
                     /protein_id="HBC0632666.1"
                     /translation="MLQVTSEQWLSWLSLYFWPLLRVLALISTAPIVSERSVPKRVKL
                     GLAMMITFAIAPSLPANDVPVFSFFALWLAVQQILIGIALGFTMQFAFAAVRTAGEII
                     GLQMGLSFATFVDPASHLNMPVLARIMDMLALLLFLTFNGHLWLISLLVDTFHTLPIG
                     GEPLNSNAFLALTKAGSLIFLNGLMLALPLITLLLTLNLALGLLNRMAPQLSIFVIGF
                     PLTLTVGISLMAALMPLIASFCEHLFSEIFNLLADIISELPLI"
     gene            complement(22153..22422)
                     /gene="fliQ"
                     /locus_tag="IRB70_002777"
     CDS             complement(22153..22422)
                     /gene="fliQ"
                     /locus_tag="IRB70_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013365797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar biosynthesis protein FliQ"
                     /protein_id="HBC0632667.1"
                     /translation="MTPESVMMMGTEAMKVALALAAPLLLVALVTGLIISILQAATQI
                     NEMTLSFIPKIIAVFIAIIIAGPWMLNLLLDYVRTLFTNLPYIIG"
     gene            complement(22432..23169)
                     /gene="fliP"
                     /locus_tag="IRB70_002778"
     CDS             complement(22432..23169)
                     /gene="fliP"
                     /locus_tag="IRB70_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310714.1"
                     /note="The bacterial flagellar biogenesis protein FliP
                     forms a type III secretion system (T3SS)-type pore
                     required for flagellar assembly; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system pore protein
                     FliP"
                     /protein_id="HBC0632668.1"
                     /translation="MRRLLSVAPVLLWLVTPLAFAQLPGITSQPLPGGGQSWSLPVQT
                     LVFITSLTFIPAILLMMTSFTRIIIVFGLLRNALGTPSAPPNQVLLGLALFLTFFIMS
                     PVIDKIYVDAYQPFSEEKISMQEALEKGAQPLREFMLHQTREADLGVFARLANTGPLQ
                     GPEAVPMRILLPAYVTSELKTAFQIGFTIFIPFLIIDLVIASVLMALGMMMVPPATIA
                     LPFKLMLFVLVDGWQLLVGSLAQSFYS"
     gene            complement(23169..23534)
                     /gene="fliO"
                     /locus_tag="IRB70_002779"
     CDS             complement(23169..23534)
                     /gene="fliO"
                     /locus_tag="IRB70_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310713.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar type III secretion system protein
                     FliO"
                     /protein_id="HBC0632669.1"
                     /translation="MNNHATVQSSTPVSAAPLLQVSGALIAIIALILAAAWLVKRLGF
                     APKRTGVNGLKISASASLGARERVVVVDVEDARLVLGVTAGQINLLHKLPPSAPTEEI
                     PQTDFQSVMKNLLKRSGRS"
     gene            complement(23537..23950)
                     /gene="fliN"
                     /locus_tag="IRB70_002780"
     CDS             complement(23537..23950)
                     /gene="fliN"
                     /locus_tag="IRB70_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliN"
                     /protein_id="HBC0632670.1"
                     /translation="MSDMNNPADDNNGAMDDLWAEALSEQKSTSSKSAADAVFQQFGG
                     GDVSGTLQDIDLIMDIPVKLTVELGRTRMTIKELLRLTQGSVVALDGLAGEPLDILIN
                     GYLIAQGEVVVIADKYGVRITDIITPSERMRRLSR"
     gene            complement(23947..24951)
                     /gene="fliM"
                     /locus_tag="IRB70_002781"
     CDS             complement(23947..24951)
                     /gene="fliM"
                     /locus_tag="IRB70_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005127760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliM"
                     /protein_id="HBC0632671.1"
                     /translation="MGDSILSQAEIDALLNGDSEVKDEPTASVSGESDIRPYDPNTQR
                     RVVRERLQALEIINERFARHFRMGLFNLLRRSPDITVGAIRIQPYHEFARNLPVPTNL
                     NLIHLKPLRGTGLVVFSPSLVFIAVDNLFGGDGRFPTKVEGREFTHTEQRVINRMLKL
                     ALEGYSDAWKAINPLEVEYVRSEMQVKFTNITTSPNDIVVNTPFHVEIGNLTGEFNIC
                     LPFSMIEPLRELLVNPPLENSRNEDQNWRDNLVRQVQHSQLELVANFADISLRLSQIL
                     KLKPGDVLPIEKPDRIIAHVDGVPVLTSQYGTLNGQYALRIEHLINPILNSLNEEQPK
                     "
     gene            complement(24956..25420)
                     /gene="fliL"
                     /locus_tag="IRB70_002782"
     CDS             complement(24956..25420)
                     /gene="fliL"
                     /locus_tag="IRB70_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar basal body-associated protein FliL"
                     /protein_id="HBC0632672.1"
                     /translation="MTDYAISKKSKRSLWIPILVFITLAACASAGYSYWHSHQVAADD
                     KAQQRVVPSPVFYALDTFTVNLGDADRVLYIGITLRLKDEATRSRLSEYLPEVRSRLL
                     LLFSRQDAAVLATEEGKKNLITEIKTTLSTPLVAGQPKQDVTDVLYTAFILR"
     gene            complement(25525..26652)
                     /gene="fliK"
                     /locus_tag="IRB70_002783"
     CDS             complement(25525..26652)
                     /gene="fliK"
                     /locus_tag="IRB70_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook length control protein FliK"
                     /protein_id="HBC0632673.1"
                     /translation="MIRLAPLITADVDTTTLSGGKASDAAQDFLALLSEALTGEATTD
                     KATPQLLVATDKPTTKGEPLVSDIVSDAQQADLLIPVDETPPVINDEQSTSTPLNTAQ
                     TITLAAAADNNTAKDEKADDLNEDVTASLSALFAMLPGFDNTPKVTDAPSTVLPTEKP
                     TLFTKLTSAQLTTAQPDDAPGTPAQPLTPLIAEAQSKAEIISTPSPVTAAASPLITPH
                     QTQPLPTVAAPVLSAPLGSHEWQQSLSQHISLFTRQGQQSAELRLHPQDLGEVQISLK
                     VDDNQAQIQMVSPHQHVRAALEAALPVLRTQLAESGIQLGQSNISGESFSGQQQAASQ
                     QQQSQRTVNHEPLAGEEDDTLPVPVSLQGRVTGNSGVDIFA"
     gene            complement(26649..27092)
                     /gene="fliJ"
                     /locus_tag="IRB70_002784"
     CDS             complement(26649..27092)
                     /gene="fliJ"
                     /locus_tag="IRB70_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis chaperone FliJ"
                     /protein_id="HBC0632674.1"
                     /translation="MAEHGALATLKDLAEKEVEDAARLLGEMRRGCQQAEEQLKMLID
                     YQNEYRNNLNSDMSAGMTSNRWINYQQFIQTLEKAITQHRQQLNQWTQKVDIALNSWR
                     EKKQRLQAWQTLQERQSTAALLAENRLDQKKMDEFAQRAAMRKPE"
     gene            complement(27111..28484)
                     /gene="fliI"
                     /locus_tag="IRB70_002785"
     CDS             complement(27111..28484)
                     /gene="fliI"
                     /locus_tag="IRB70_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellum-specific ATP synthase FliI"
                     /protein_id="HBC0632675.1"
                     /translation="MTTRLTRWLTTLDNFEAKMAQLPAVRRYGRLTRATGLVLEATGL
                     QLPLGATCVIERQNGSETHEVESEVVGFNGQRLFLMPLEEVEGVLPGARVYAKNISAE
                     GLQSGKQLPLGPALLGRVLDGSGKPLDGLPSPDTTETGALITPPFNPLQRTPIEHVLD
                     TGVRPINALLTVGRGQRMGLFAGSGVGKSVLLGMMARYTRADVIVVGLIGERGREVKD
                     FIENILGAEGRARSVVIAAPADVSPLLRMQGAAYATRIAEDFRDRGQHVLLIMDSLTR
                     YAMAQREIALAIGEPPATKGYPPSVFAKLPALVERAGNGISGGGSITAFYTVLTEGDD
                     QQDPIADSARAILDGHIVLSRRLAEAGHYPAIDIEASISRAMTALISEQHYARVRTFK
                     QLLSSFQRNRDLVSVGAYAKGSDPMLDKAIALWPQLEGYLQQGIFERADWEASLQGLE
                     RIFPTVS"
     gene            complement(28484..29170)
                     /gene="fliH"
                     /locus_tag="IRB70_002786"
     CDS             complement(28484..29170)
                     /gene="fliH"
                     /locus_tag="IRB70_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707825.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar assembly protein FliH"
                     /protein_id="HBC0632676.1"
                     /translation="MSDNLPWKTWMPDDLAPPPAEFVPIVEPEETIIEEAEPSLEQQL
                     AQLQMQAHEQGYQAGIAEGRQQGHEQGYQEGLAQGLEQGLAEAKAQQAPIHARMQQLV
                     SEFQTTLDALDSVIASRLMQMALEAARQVIGQTPTVDNSALIKQIQLLLQQEPLFSGK
                     PQLRVHPDDLQRVDDMLGATLSLHGWRLRGDPTLHPGGCKVSADEGDLDASVATRWQE
                     LCRLAAPGVV"
     gene            complement(29163..30158)
                     /gene="fliG"
                     /locus_tag="IRB70_002787"
     CDS             complement(29163..30158)
                     /gene="fliG"
                     /locus_tag="IRB70_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein FliG"
                     /protein_id="HBC0632677.1"
                     /translation="MSNLTGTDKSVILLMTIGEDRAAEVFKHLSQREVQTLSAAMANV
                     TQISNKQLTDVLAEFEQEAEQFAALNINANDYLRSVLVKALGEERAASLLEDILETRD
                     TASGIETLNFMEPQSAADLIRDEHPQIIATILVHLKRAQAADILALFDERLRHDVMLR
                     IATFGGVQPAALAELTEVLNGLLDGQNLKRSKMGGVRTAAEIINLMKTQQEEAVITAV
                     REFDGELAQKIIDEMFLFENLVDVDDRSIQRLLQEVDSESLLIALKGAEQPLREKFLR
                     NMSQRAADILRDDLANRGPVRLSQVENEQKAILLIVRRLAETGEMVIGSGEDTYV"
     gene            complement(30151..31809)
                     /gene="fliF"
                     /locus_tag="IRB70_002788"
     CDS             complement(30151..31809)
                     /gene="fliF"
                     /locus_tag="IRB70_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar M-ring protein FliF"
                     /protein_id="HBC0632678.1"
                     /translation="MNATAAQTKSLEWLNRLRANPKIPLIVAGSAAVAVMVALILWAK
                     APDYRTLFSNLSDQDGGAIVSQLTQMNIPYRFSEASGAIEVPADKVHELRLRLAQQGL
                     PKGGAVGFELLDQEKFGISQFSEQVNYQRALEGELSRTIETIGPVKGARVHLAMPKPS
                     LFVREQKSPSASVTVNLLPGRALDEGQISAIVHLVSSAVAGLPPGNVTLVDQGGHLLT
                     QSNTSGRDLNDAQLKYASDVEGRIQRRIEAILSPIVGNGNIHAQVTAQLDFASKEQTE
                     EQYRPNGDESHAALRSRQLNESEQSGSGYPGGVPGALSNQPAPANNAPISTPPANQNN
                     RQQQASTTSNSGPRSTQRNETSNYEVDRTIRHTKMNVGDVQRLSVAVVVNYKTLPDGK
                     PLPLSNEQMKQIEDLTREAMGFSEKRGDSLNVVNSPFNSSDEGGGELPFWQQQAFIDQ
                     LLAAGRWLLVLLVAWLLWRKAVRPQLTRRAEAMKAVQQQAQAREEVEDAVEVRLSKDE
                     QLQQRRANQRLGAEVMSQRIREMSDNDPRVVALVIRQWINNDHE"
     gene            32024..32338
                     /gene="fliE"
                     /locus_tag="IRB70_002789"
     CDS             32024..32338
                     /gene="fliE"
                     /locus_tag="IRB70_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar hook-basal body complex protein FliE"
                     /protein_id="HBC0632679.1"
                     /translation="MSAIQGIEGVISQLQATAMSARAQDSLPQPTISFAGQLHAALDR
                     ISDTQTAARTQAEKFTLGEPGVALNDVMTDMQKASVSMQMGIQVRNKLVAAYQEVMSM
                     QV"
     gene            32682..33014
                     /gene="emrE"
                     /locus_tag="IRB70_002790"
     CDS             32682..33014
                     /gene="emrE"
                     /locus_tag="IRB70_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family multidrug efflux protein EmrE"
                     /protein_id="HBC0632680.1"
                     /translation="MNPYIYLGGAILAEVIGTTLMKFSEGFTRLWPSVGTIICYCASF
                     WLLAQTLAYIPTGIAYAIWSGVGIVLISLLSWGFFGQRLDLPAIIGMMLICAGVLVIN
                     LLSRSAPH"
     gene            33183..33734
                     /gene="ybcL"
                     /locus_tag="IRB70_002791"
     CDS             33183..33734
                     /gene="ybcL"
                     /locus_tag="IRB70_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Raf kinase inhibitor-like protein YbcL"
                     /protein_id="HBC0632681.1"
                     /translation="MKKLIVSSVLAFITFSAQAAAFQVTSNEIKTGEQLTTSHVFSGF
                     GCEGGNTSPSLTWSGAPEGTKSFAVTVYDPDAPTGSGWWHWTVANIPATVTYLPADAG
                     RRDGTKLPTGAVQGRNDFGYAGFGGACPPKGDKPHHYQFKVWALKTDKIPVDSNSSGA
                     LVGYMLNANKIATAEITPVYEIK"
     gene            33744..34541
                     /locus_tag="IRB70_002792"
     CDS             33744..34541
                     /locus_tag="IRB70_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0632682.1"
                     /translation="MLAKDKTNLKIEEIRMHKHHEIHRVKPLMPALCRIRQGKKVINW
                     ETHSLTVDNNQIILFPCGYEFYIANYPEAGLYLAEMLYYPIDLIEKFQKFYAITDQIR
                     NTTGFCLPQNPELIYCWEQLKTSISRGFSTQIQEHLAMGVLLSLGAHHVNCLLLSDSK
                     QSLISRCYNLMLSEPGTKWTANKVARYLYISVSTLHRRLASEGVSFQSILDDVRLNNA
                     LSAIQTTVKPISEIARENGYKCPSRFTERFHNRFKITPRELRKASRE"
BASE COUNT         8912 a         8295 c         8688 g         8962 t
ORIGIN      
        1 gacggaagtc actgtcgttc tcaaaatcgg tggagctgca tgacaaagtc atcgggcatt
       61 atctgaacat aaaacactat cagtaagttg gagtcattac cgggacggag tagagaagat
      121 aatgctgaac tctttgccag cagaaggtta tgtggaacaa aaataaccgt aacttctcac
      181 tctcgacagg aaagctgtag acggcgtcca taacaaaacg cccccaacca taaggtcgag
      241 ggcgcttaag atgacaaacc cgctcttcgt taaagaatca atgcttaatg tagatgagtt
      301 gcattgcacg ataaaagcga aatttttaga atttggctcc tctgactgga ctcgaaccag
      361 tgacatacgg attaacagtc cgccgttcta ccgactgaac tacagaggaa tcgtgagaac
      421 gaggcgcata ttacttagcg gtgccgcgtc tgtcaacacc aaatttcata agttatttca
      481 actggttaat taatctgcaa acttgttaat taatgaacat tcgtcgccga aaaagagtct
      541 gtatcattag catgacgtag tctctgcaaa ggatcttgtt gataaaattg gcagaaacgt
      601 tgccacaatg aagggaaacg aggagcaaaa agctcagggg cgctaaagaa atattcagaa
      661 agtacggcaa aacactcagc aggatcactg gcagcataag catcgatgct cgccgcattt
      721 tcaccgacta attcgatctc ttcctgaatg ttgttcattg cggcatgaag atcgtgttcc
      781 cagccagcaa cctcacgcaa cggaataaag ggaactccgc tggcgcgatc gccgttacgg
      841 gtgtccagct tatgagcgac ttcatgaata atcaggttaa aaccagaagc atcaaacgaa
      901 tcttgtatat ccaaccagtt caaaacgatt ggcccttgct gccagctctg acctgactga
      961 acaatacgtt ggttatgcac taaaccgata tcgtcttccc actcatcatc gaccacaaat
     1021 ggcgcagggt aaattaagac ttcatgaaaa ccatccagcc attctagccc taactccaga
     1081 acgggcaggc aaaatagaag ggctatccgg cagcttctta gtgaatccag ctcaaagccc
     1141 tgtaagggaa caagccgttt ttgctgtaaa aaacgttcgg caagagtgac taatttgctt
     1201 tgttcctgtt ccgtcagaca cgttaaaagg gggatcgata gtgcttcctg ccagggaagg
     1261 gcagtttgat gtgctgattc ttgtactttc cagggccact taatcatcgt tttgctcgca
     1321 aactcgtcac ttgaacaaaa ttgcacggac agggactgtt aaaatgccaa atttcctggc
     1381 atcatggcaa ccatctgaac ggagagatgc cggagcggct gaacggaccg gtctcgaaaa
     1441 ccggagtagg ggcaactcta ccgggggttc aaatccccct ctctccgcca ctttatcaat
     1501 gacttatctc ctaacttccc gccttgcttt ttcttaacag aacaatcgta gaatattctt
     1561 gaaggtttag atcgtcactg ttttctgttc gatactgtga cattcagcac ttgattcgct
     1621 atggatcaga caggaaggtt tcgagcgaaa atctactgtt attcagtcgt tttcttatcg
     1681 gtcaccatta ttcttttaga cattgatcct atgaaactgc cgcaaagttg gtggcgggaa
     1741 ctgaagttgc gtagagatgg ggtcaataat tgagccaaaa aaggaacgcg gccgtcagat
     1801 taaagccgcg ggacaaaatc cataatttcc aagagttgtt gaatttccca gcttttttga
     1861 aagcctttgt atcatactaa caagtaaaaa aggtttaaat accaaaatta acctgtattt
     1921 ttgataagtc ttaccattgt acgatttaca cagtttctgc tcctccttgt tgatagtgga
     1981 aagagtgcgg tatgcacttg cgtaaacatt tatgatgcgt tgatgtccag ggttcacatt
     2041 tccttgtcag gggatcgact tatttgtggc gaggcatcat tcgtaacaga gtattatctt
     2101 tctgaatgta atgatgaaag agcgctgcgc cagcgtgggc tgcgattaaa aagtaaccta
     2161 tgttcgccca ggtttcgtga atatttttta tcaatgcttt aatttcactg tttggggtaa
     2221 caaaaggcgg cacattgaaa ccaaggaaac tccacgattt tccactataa gccattaaag
     2281 caatccccaa cagtggaagc gcaaggaagg ttatataaag catgatgtgc attagcgaag
     2341 ccgctttcat ttgccaggca ggtggcggtg gcacaataga gggatcactg taacggtgtt
     2401 ttattataag gcgtaaaaac attaacaccc aaacgaagat acccgcattg taatgtgttt
     2461 cacgcatcaa cagataagta ttactacctt tgggaaacca gccacggagt tccattgcgg
     2521 cataagtgat tgcaatgaaa agcagcgtta tccagtgtaa ataaatttga gtttttgaga
     2581 atcgattcat ttttatagct cctgtaattt tcacagtcaa gctatcccac gaaccttaaa
     2641 aataccttat acagatgtgg ttttaagaat ttgttattta aaaaattgaa aagggtaaat
     2701 tgtgaacagt caatataagc aattgcctgc gcccagttat cttacgctgt tggcagtatt
     2761 gtatatggag tccgttattg attaacccta tgagggcttg cttattaaga tgcagacacg
     2821 tcatagcgat gagcgtgtct gcagctacct tgcattcagt ggcgtttgtg gatggacctg
     2881 tggctgctat gataacttaa taaaaacggc atcgagacgc tattcatgga agactcaatg
     2941 agacatcatc tcctcgacca cttcttcgct actcaactga tagggataat acgttggcca
     3001 gttttccatt tcattcaata aagattgctg tgaatcatta cccataaaaa tgtgaaaatg
     3061 agatgatttt cgtggtgcaa ttatatgatc gctaaattgt atatatttag gggctttgct
     3121 ttcaggatct ttacattcga ataagtaacg aacgcctttc ttgcctgatt tataggtgag
     3181 tattttgtat ccatcgtaat catatttaca ggatgttgtt tcattatttc tatggaattc
     3241 aacaatgccg tcctcaatgc caatcatctc gatatctgtt gcataacctt tgtgataata
     3301 atctttaatt tcagcaaatg ttttagtttt atctgcatcc gctttcttct gaaagacggg
     3361 gtcaagtttg ccactttgca gtaaaggata aacggattgc cagactccat cccagtcact
     3421 gagcgttcgg ttttgtacat tggcatcatc aaaaacacca ttagcagctt tttgttcgac
     3481 ctctgttaag ggtttgccgt gtgagtgatg accatgcgaa aaggcaggag cgctaacaat
     3541 aaagacacct aaagcaacag ccagtttgtg aagacgaatc gccaaaacag tttcctccag
     3601 agtcattgta tatgatgtgt aatgttatat tgtaacatat gacaaaatgc aacaactctt
     3661 aggagatgag agcatagttt tctcaggtgt acttatctat cttattgaaa taagatgaat
     3721 taggttgata atttgaggtt gatgacaaac gaaacataac ctgatgtgat ctgcgtaggc
     3781 cggatagggc gctcgcgccg catccggcag ggataacgcg tactttgtcg gcaatatgaa
     3841 gttatacaga taatttgttg tgaacctgct tgcgtaaccg gttaaaaagg gaacgcaact
     3901 tcttataccg taaggctaaa agcagtacag ccagcccagc gtagatgagc ggctgcggtg
     3961 aaataatctt cactgaccac agataatgta ttggggccag gatcgcgaca agatagacga
     4021 aattatgcaa ctgttgccag tgcttgccga gttttcgctg catcgcctgg gttgaagtaa
     4081 acgctaaagc aagcaaaata acccagctga taattcctaa cgttaaataa ggccgggtaa
     4141 ttaactcctt acctaataac gccagattat tcacgcccag ctccagcaat gcgtaactgg
     4201 ttaaatgcag tgtcgcccag gcaaagcacc ataagcctaa caggcggcga gtgcgtatca
     4261 ataacggctg ttttgcgtag cgtgccagag gtgtgattaa caaggtcgcc agcaaaaatt
     4321 tcagtgcagt gcgaccggta aaatgctgaa tatctttcac cggatcggca cccagtccac
     4381 cgtgattgat cgcccagacc agccagagaa acggcaacaa tccggcaaga tgcaggctaa
     4441 ctttcagcca tgtcacctgt tttgctgtca gacgcattca gaaattctcc cgcaaatcca
     4501 ggccacgata cagcgatgcc acctggtcgg cgtaaccatt aaacagtagc gttggctggc
     4561 gctgtacatc gaggatgccg cctgaaccaa taaatcgttc ggtagcctgt gaccagcgcg
     4621 ggtgatcaac atgcggatta acgttggcgt aaaaaccgta ttcgtcaggc gctgccagat
     4681 tccaggtggt tggcggacgc tcgcgggtca gcttaatact gactatcgat ttaatccctt
     4741 taaagccata tttccacggc acaatcagtc gtaccggcgc gccattttgt ggcggtaacg
     4801 ccttgccata aacacccacg gtcatcagtg tgagcggatg cattgcttcg tcgagacgca
     4861 atccttcgac ataaggatat ttcagcccgc cgccgataaa gcggtcctgc tgaccaggca
     4921 tctgttccgg tgcataaatt gtttcgaaag cgacatactt cgcattgctg gtgggttcgg
     4981 caagcgccag caatttgtgc agcggaaaac caatccacgg caccaccatc gaccacgctt
     5041 ccacgcagcg catacgataa atacgctctt ccagcgggaa gcgacgggtt aaatcatcgt
     5101 gatcgagggt caatggtttt gccacttcgc cgctgatttt cagtgtccat ggatcggttt
     5161 tcaggctacc agcattagcg gcgggatcgg ctttatccag cccgaattca tagaagttgt
     5221 tatagccgga aactttatct gctggcgtca gtggcaggtt attttgccag gcggcaggct
     5281 tgctgaactc cagcggtttt ccggcggggg cgggtgggcg atcgttccct ttaaaccagc
     5341 taagcagatc ggcatgcgca gcgtgaggca aagaaagtgc agctgcgctg atgcccagtg
     5401 cttttaacac ctgccgacgc ttcataaaga ataccgactc ggccgtaaca tctgattctt
     5461 ttaaaaattg attctttttc ataagccatc acactttttt gtcgttagcc agcaagagcc
     5521 gtttactgtt aatctgtcag ggagtgtcct ccctaacagt agcagagatc tgcttttaca
     5581 tatttatgct ttaactgcca cgataggttg aatacccata ttggctaagt aataaaggca
     5641 catgataatg ctcgttcact ttattaatat gaaattcaac ggggatctca gggaagaaac
     5701 tttcaagatt ttgtttcttg aaatagtccc cggttttaaa tacgacacgg taatcgccag
     5761 tagtcgcagt ttgctcgggc cacagtgcct taattcgtcc atccttatct gttttggcgg
     5821 tattaagttg taaccagccg ttatccgcct tcttttcaag agtgactgtc acgtcagcag
     5881 cgggttttcc ggtttgctgg ttcaaaatat gcacgctaag aatgttttgt tgtgcggcat
     5941 aaaccaaaga aggtaatgaa aatgctgccg ttgctaccga gagtactaaa taacgcttta
     6001 acatgtttat atccttgtca tgtgaatgag ttttgaggat agcgaaaaag cggccagggt
     6061 aaccttacag cagcattaca attttgtaat ggaccaggct gtttctataa catatgattt
     6121 atggcatatt attttcatga agattttact tattgaagat aatcaaagga cccaggagtg
     6181 ggtaacgcag gggctttccg aagcgggtta tgtcattgat gccgtttctg atggcagaga
     6241 tgggctttat cttgcgctga aggatgatta tgcattgatc attctggata ttatgcttcc
     6301 gggtatggat ggctggcaga tcttacaaac gttaagaaca gcaaagcaaa cccctgttat
     6361 ttgccttact gcaagggatt ctgtcgatga cagagtcaga gggctggaca gtggagcaaa
     6421 tgattatctg gtaaaacctt tttcattttc tgagttgctg gcaagggttc gggcacaatt
     6481 aaggcaacat cacgctttga attcaacatt agaaatcagt ggcttaagaa tggactctgt
     6541 aagtcaaagt gtgagcaggg acaatatcag tattacactg acgcgcaagg agtttcagtt
     6601 actttggcta ctggcctcca gagctggcga aattataccc agaacggtta ttgcgagtga
     6661 aatttgggga atcaactttg atagtgatac caatacggtg gatgtcgcca ttcgcaggct
     6721 ccgcgcaaaa gttgatgatc cttttcctga aaagctaatc gccacaatcc gggggatggg
     6781 ctattcattc gtagcggtaa aaaaataatg aaaagattgt ctataaccgt ccgtttaacc
     6841 ttgcttttta tattgctgct gtctgttgct ggcgctggaa ttgtatggac tctctataat
     6901 ggcctggcaa gtgagttgaa atggcgcgat gatacaacac tcattaaccg gacagcgcag
     6961 atcaagcagt tgttaattga tggggtaaat ccagatacgt tacctgtgta ctttaaccgg
     7021 atgatggatg ttagtcagga tatcttgatc attcatggtg atggcatcaa taaaattgtt
     7081 aaccggacga atgtcagtga tgacatgtta aataacatac ctgctagtga gacaatcagc
     7141 gcagctggca tttacagaag cattattaat gatacagaga tagatgcttt acgaattaat
     7201 attgatgaag tttcgccatc attaacggtt actgtggcta aattggcttc agccagacat
     7261 aacatgcttg aacagtataa aattaatagc attataattt gcattgtcgc cattgtactt
     7321 tgctcagtat taagtccgct gttaatcaga acgggattac gagagatcaa aaagttgagt
     7381 ggtgtaacgg aagcgctgaa ttataacgat agccgggagc ctgttgaggt tagcgcatta
     7441 ccgagagaac taaaacctct tgggcaggcg ttgaataaaa tgcatcaagc cttagtcaaa
     7501 gattttgaac gcctaagtca atttgctgac gatctcgctc atgaacttag aacgcccatt
     7561 aatgcattac tgggtcagaa tcaggttacg ctcagtcaaa ccagaagtat cgctgaatat
     7621 caaaaaacaa ttgccggtaa cattgaagag ctggaaaata tttcgcggtt aacagagaac
     7681 atactgtttc ttgcccgggc agataaaaac aatgttttgg tgaaactgga ctcgctttct
     7741 ctcaataagg aagtcgaaaa tttgttggat tatcttgaat acctttcaga cgagaaagag
     7801 atttgcttta aggtcgagtg caatcagcaa atctttgcgg ataaaatttt actgcaacga
     7861 atgttatcga atcttattgt taatgccatt agatattcac cagaaaaatc gcgtattcat
     7921 ataaccagtt ttcttgatac caacggctat cttaatattg atgtcgccag tcctggaacg
     7981 aaaattcatg agcctgaaaa actcttccgt agattttggc ggggagataa ttcgcgtcat
     8041 tccgtaggtc agggacttgg tctttcttta gtcaaagcga ttgccgaatt acatggggga
     8101 agtgctacgt atcactatct caataagcat aatgtgttcc ggattatgtt accgcaaaga
     8161 aattaacata gggcttcagt acgccataaa tcaaccatga aaaaacgcag ccacgtcgtg
     8221 agtattaacg tggctgcgat tgattatgcg cttacattca tacgtaacag ggattaaccc
     8281 gcataagctg ccagcatttc ctgcgccgcc agtttaccca acgcattcgc tgcgaaagga
     8341 ctgtcgccgg tgagaacttt acggtcctta tgtactcgcc cggtgatgtc gtcattaata
     8401 atgttcatgc ccattttctt cagctcttcg ccgaagtacc aggtgagatg acccggcata
     8461 tagcctatct ctggcgtttg tttgtctgcg gcgtctggga atgcgcaaat ggaataacca
     8521 ttcagtgggt tatcgccgtg gcgaagcgcc agaaaagccg ccgggccgtg gcaaagggag
     8581 ataacaaaac ggtcattttt gattgcccac tgcaaagcag cagctacgtc ctggctttct
     8641 ggtaaaccaa taagtgcgcc atgaccacca ggaacaaaga ttgctgcata ttcgctgtca
     8701 gcgttgaggc tggcgacaac atccgcgagt ttcttcggat tgcggaacaa cgatttatgt
     8761 tgctcaaaga atggcattac tttttcatct ttgtgcggca tagcccagta ttcaaacttg
     8821 gtcatcagac cggaaatggt cgccacttcg aattcgaaac ctgcagcatg gagatgatac
     8881 aacggcagca acgtttcaat cggatggtta ccggtcgaga acagttttcc gttatcggtt
     8941 ggcaaataac gttcgtccgc ggcgatcacc agaattttat gcttaccgcg atacggtttt
     9001 ggatagtcca cgccatcaag atcagagacg ggactggtat attggctaag cgaatattct
     9061 gaagggaaga atgcattatc ttcagcaata tcgacctgcg gatttttact tgtttgaaca
     9121 gtcatagtgt attccttatt gttgcttagt tagggtagtc actatatttg cgactgagct
     9181 ggtcgctatt tttaaccagt ctggaaaatt gagtcaatat atcgaaagcg gtagtcggcg
     9241 ggtgtaagta tgtaatgatg atgctgcact ggtgttgaat attattcacg ccaaattttc
     9301 cttattgagc aacgtcgtcg caagtggcct caatgatttt agaccattat caaaggtacg
     9361 gggcggcggg gagagattta gtgctgtgaa atattgtggt actgatgaat atttatatcg
     9421 cggattggta gagaaaagat tatttcatgc actatttttg caaatatttc tatatgggaa
     9481 gcgtgtttgt tacggattaa ttcataaaga aatgcatttg ggtgttggtt tgaagagtcg
     9541 ctggttgatg ttattgtgcc aggaggggca gggtaaggtg ctgtatcgat atgcattggc
     9601 aattgcgtgt gccgcagatg gagatgaaat gccaataaaa aagcctgaat tcgatgaggg
     9661 acgaactcag gctagtgttt agttttacag taacacgccg cagcacgttg gctgattaga
     9721 actggtagac taagcccaca gcaacgatat catcggtagc gatgccgttg tttgcgtaga
     9781 agtcatcgtc gttgtccagc aggttgattt tgtaatcaac ataggtggac atgtttttgt
     9841 taaagtagta gattgcacca acctcaacgt atttaaccag atctttattg gtataatgat
     9901 aattaccatt gttgtacatt tcttgaccac ctaaatcctt acctttagat tggaggtaag
     9961 caattgaagg acgcaggccg aaatcaaatt ggtactgagc aacaacttca aagttctgag
    10021 ttttgttagc gataccaccg ccgccaagtt tcccatcggc tgaatgagag tcgctgctac
    10081 cataagcggt catattgcga gtctctgcat acattgctgc taaatataca ttgttggcat
    10141 cgtatttagc accaacagtc cacgcttctg cagtaccacc acctgcatag ctattaccat
    10201 agaaatgatt gccatctcca tacccacgag cagcttggtt attggaacgg tcagaattag
    10261 agtaagcagc acccagactt aaaccgaagt cgaagtcgta ggaagtagac ataccgaaac
    10321 catcgccatt ttctttagca agactacggc catctccgct gccagatcct tcttggccaa
    10381 agagaccgtc actgccactt tcattattac tctgatattg cagcgcaaag ttcaagccat
    10441 caacctgacc aaagaagcca ttgttacggt aggttgcaac accgttggta cgaccgttca
    10501 tgaaattgtc ggcaccagca taggtatcgc caccaaattc tggcagcata tcggtccatg
    10561 cttcgatgtc atatacgaca ccgtagttac gaccataatc gaaagtacca ttctgaccaa
    10621 aacctaaacc tgcgaaagcc agacgggtag cagagttatc tccatcgcct tctgtgccat
    10681 ttgcttgcag gttgtattcc cactgaccat aaccagtgaa ttggtcagcg atctgagttt
    10741 cacctttgaa accgatacgg gcatatgact tgtcgccatc gctgccagca tcatcagaga
    10801 agtagtgcag gcccgctact tttccgtaca aatccagttt attaccatct ttattataga
    10861 cttcagccgc atttgctgcg ccagcaacta ataacgccgg gaccagcatt gccagaactt
    10921 ttcttttcat tatgtattcc cttgtgatta taatcttcat gaatatatca ataagtgccg
    10981 ttatccaaaa aaagcacatt tggatactat tctatgaagt tcattttatt ttaaggatta
    11041 catgtaacag atgtatttaa aagatttcaa aatgtttcta atctatttaa tataattcag
    11101 gattatgaat tctgaatata aacattcatg aatattataa atgcatatca ataagttatg
    11161 agttgagcag aaagataggg ggtatcaatg attgttgcgc taaacacctg gtgtgatcac
    11221 gcgcacatta atgaaggcat aaaaaaaagc cggcatcatg ccggcccaaa aaatattaac
    11281 aagacgataa aaggctaata acgtaagcat catgacacag aataataaaa aggtataatt
    11341 gtaatcagtg ctaatatatt gattaaatga attaataaag ccgatatcaa agataaataa
    11401 aatcgctcaa aacgattttt cctgtattca ctgccgttgc gcaaaaatta tctatttgtt
    11461 caaaaaatga gtgagtcttg actggctcat ccaatgtgga aaaatgtgac ttttatcaca
    11521 taatagtact aagtctgagt tttccgggtt atctcaaaat ggaatacggt tcgacaaaga
    11581 tggaagagag actctctcgc agccctggcg gcaaactggc tttgtgggct ttctatacat
    11641 ggtgtggcta tttcgtctgg gcaatggcgc gttacatctg ggtgatgagc cggatccccg
    11701 atgcccccgt gtcgggattt gaaagcgatt taggctctac cgcgggaaag tggttagggg
    11761 cactggtcgg atttttattt atggctctgg tcggggcatt gttaggcagc attgcctggt
    11821 acacccgacc tcgtcccgca cgtagcagac gctatgaata aaaactgcta aggtggcgac
    11881 tctttggcaa cggagcgcgt atggacttac aacactggca ggcacagttc gaaaactggt
    11941 tgaaaaacca tcatcagcac caggacgcgg cccatgacgt gtgtcatttt cgccgcgtct
    12001 gggctacggc acagaagctg gcggcagatg acgatgtcga tatgctggtg attttaaccg
    12061 cctgttattt tcacgatatt gtgagcctgg cgaaaaatca tccgcaaagg cagcgttctt
    12121 caatcctggc ggcagaagag acgcgtcgcc tgctccgtga agagttcgag caatttccgg
    12181 cggagaaaat cgaggccgtt tgtcatgcca ttgccgctca cagtttcagc gcgcaaatcg
    12241 cccccttaac aacggaagct aaaattgtcc aggatgcgga tcggctggaa gccctggggg
    12301 cgattggcct ggcgcgcgtg tttgccgttt caggggcatt gggcgtggcg ctgtttgatg
    12361 gtgaagatcc gttcgcacag catcgcccgc ttgatgataa acgctacgcg ctggatcatt
    12421 tccagactaa gttgctgaag ctaccgcaaa ccatgcaaac cgcaagaggc aagcagctgg
    12481 cgcagcacaa cgcgcatttt ttagtcgagt ttatggcgaa gctcagtgcc gaactggcgg
    12541 gggagaatga aggtgtcgat cacaaggtga tagatgcgtt ttcatccgct ggctgagcgc
    12601 gtggccctaa atggctgtaa ttatgttaac ctgtcggcca tctcagatgg ccggtgaaat
    12661 ctatgcagga aaatatatca gtaaccgatt catacagcac cgggaatgcc gcacaggcaa
    12721 tgctggagaa actgctgcaa atttatgatg ttaaaacgtt ggtggcgcag cttaatggtg
    12781 taggtgagaa tcactggagc gcggcaattt taaaacgtgc gctggcgaat gactcggcat
    12841 ggcaccgttt aagtgagaaa gagttcgccc atctgcaaac gttattaccc aaaccaccgg
    12901 cacatcatcc gcattatgcg tttcgcttta tcgatctatt cgccggaatt ggcggcatcc
    12961 gtcgcggttt tgaatcgatt ggcggacagt gcgtgtttac cagcgaatgg aacaaacatg
    13021 cggtacgcac ttataaagcc aaccattatt gcgatccggc gacgcatcat tttaatgaag
    13081 atatccgcga catcaccctc agccataaag aaggcgtgag tgatgaggcg gcggcggaac
    13141 atattcgtca acacattcct gaacacgatg ttttactggc cggtttccct tgtcagccat
    13201 tttcgctggc tggcgtatcg aaaaagaact cgctcgggcg ggcgcacggt tttgcctgcg
    13261 atacccaggg cacgctgttt tttgatgtgg tacgcattat cgacgcgcgt cgtccggcga
    13321 tgtttgtgct cgaaaacgtc aaaaacctga aaagtcacga ccagggtaaa acgttccgca
    13381 tcatcatgca gacgctggac gaactgggct atgacgtggc tgatgcagaa gataatgggc
    13441 cagacgatcc gaaaatcatc gacggcaaac attttctgcc gcagcaccgt gaacgcatcg
    13501 tgctggtggg ttttcgtcgc gatctgaatc tgaaagccga ttttaccctg cgtgatatca
    13561 gcgaatgttt ccctgcgcag cgagtgacgc tggcgcagct gttggacccg atggtcgagg
    13621 cgaaatatat cctgacgccg gtgctgtgga agtacctcta tcgatatgcg aaaaaacatc
    13681 aggcgcgcgg taacggcttc ggttatggaa tggtttatcc gaacaatccg caaagcgtca
    13741 cgcgtacgct gtctgcgcgt tattacaaag atggcgcgga aattttaatc gatcgcggct
    13801 gggatatggc caaaggtgag aaagactttg acgatccgca gaatcagcaa catcgtccac
    13861 gtcggttaac gcctcgggaa tgcgcgcgct taatgggttt tgaagcgccg ggagaagcga
    13921 aattccgcat tccagtttcg gacactcagg cctatcgcca gttcggtaac tcggtggtcg
    13981 tgccggtctt tgccgcggtg gcaaaactgc ttgagccaaa aatcaaacag gcggtggcgt
    14041 tgcgtcagca agaggcacaa catggccgac gttcacgata aggccactcg cagcaaaaat
    14101 atgcgcgcga ttgccacgcg tgatacggcg atagagaagc gcctcgccag tctgttaacc
    14161 gggcagggcc tggcatttcg cgttcaggac gccagtctgc ccggacgtcc ggattttgtc
    14221 gttgatgaat atcgttgcgt gatatttacc cacggctgct tctggcacca tcatcactgc
    14281 tatctgttta aagtgcctgc gactcgaacc gagttctggc tggagaagat aagtaaaaat
    14341 gttgaacgcg atcgccgcga tatcagtcgt ttgcaggaac tcggctggcg cgtattgatt
    14401 gtctgggagt gtgcattacg tgggcgcgag aagctgacgg atgaagcgct taccgagcgt
    14461 ctggaagagt ggatctgcgg cgaaggtgcc agcgcgcaga tcgacacgca ggggattcat
    14521 ttactcgctt gatgcgtcct gaataactgg cgcaactacg ggttttgccg ggaagagata
    14581 ttttcccaac gtgaccagta ccaccgcgaa gacaattacg ccgagcgcca gccattcaat
    14641 cttcgacagc gtttctccgc ccagtcccgt acccagcaag accgcgacca ccgggttaac
    14701 gtaggcgtag ctggtggcga gagccggact gacgttgcgg attaaataca tataagcgtt
    14761 aatggcgata atcgaaccaa acagcgccag atagccgacc gcaaggaagc ctgaaaggga
    14821 agggagcgcc gtcagttttt cacctgcaat catcgacgcg atcattaaca ccacgcctgc
    14881 cgccagcatc tcaatcgcac ccgccatcat ccctacaggt aaggtaatgc gcgagccata
    14941 aactgagcca aacgcccagc taatcgagcc gattaaaatc agaatcgcgc cccacggatt
    15001 gccgcttaaa tttccaccgc tattgagcat gatgattccg gcaagcccaa tggcaatacc
    15061 cacccattcc agtttgcgcg ttttaatgcc aaacaggcgg ctgaagcaca gggtaaagag
    15121 gggtacggtt gcaaccacta cggcggcgat gccggaagga acattttgat gttcggcaac
    15181 cgtcaccatg ccattaccga cagccagcaa taacaggcca atcagcgcgg cattgagcag
    15241 cggacgtagc ggggggagtt tgtgtccgcg cagtagcaaa aatgccagca ataaaatacc
    15301 ggctgccagg aatcgaacgc ccgccatcat taacggaggc cagctttcca cgccaatccg
    15361 aatgacaaaa taggttgagc cccaaatgat atacaacgca aacagcgcgc caaaaagcgg
    15421 taacaactgg cggaaacgca taatccctca cggtggaaat aaaaaggtgg ttcatagtaa
    15481 acgtgaaaat cattctgctg gcgagagata taattgcact tgattgttaa aaaaatgttg
    15541 acctgtgaag caagtatcag agctgccgtt tttgcttcat acttacaccc ttcaacaata
    15601 aaaatgagag ggaatgcttt tggccgggag tagtttactg acgttgctcg atgatatcgc
    15661 cacactgctg gacgatatct ccgtgatggg caaactggcg gcgaagaaaa ccgccggtgt
    15721 attaggggat gacttatcgc tcaatgcgca acaagtttca ggcgtgcggg ccaaccggga
    15781 acttcccgtg gtctggggcg tggcgaaagg atcgctgatt aataaagtga ttctggtgcc
    15841 gctggcgctg atcatcagtg cgtttatccc gtgggcgatt acgcctctgt tgatgattgg
    15901 tggcgcgttt ctctgctttg aaggagtaga gaaagtgctg catatgctgg aggcgcgtaa
    15961 acataaagaa gatccggcgc agagccagca gcgtctggag aagctggcgg cgcaggatcc
    16021 gctgaagttt gaaaaggaca aaataaaagg ggcgattcgt accgatttta tattgtctgc
    16081 cgaaatcgtc gccatcacgc tggggattgt ggccgaagcg ccgttgctta atcaggtgct
    16141 ggtgctttca ggcatcgcgc tggtagtgac cgtgggcgtc tacggtctgg taggggttat
    16201 cgttaagatt gatgacctgg ggtattggct ggcggaaaaa tccagcgcgc tgatgcaggc
    16261 attaggtaaa gggttattga tcattgcgcc ctggttgatg aaggcgttat cgattgtcgg
    16321 cacgctggcg atgttcctcg tcggcggcgg gattgtggta catggtattg cgccgctgca
    16381 tcacgccatt gaacatttcg ccgggcagca aagtgcagtg gtggcgatga tattaccgac
    16441 tgttttaaat ctgattcttg gatttatcat cggcggcatc gtggtgctgg gagtgaaagc
    16501 cgtagcgaaa atacgcggtc aggcacatta atactcgcac aggctattat gcaaaattcg
    16561 ccatcttcaa ctaaggtgaa caagtttcac tcgaaaaaag gaggcgagta tgagctttat
    16621 ggttagtgag gaagttacgg ttaaagaggg cggcccgcgg atgattgtca ccggatactc
    16681 cagcggtatg gttgagtgtc gttggtatga cggttacggg gtcaagcggg aagcttttca
    16741 tgaaaccgag cttgttccgg gggaggggag tcgttctgcg gaagaagttt gaaagggtat
    16801 cattaacacc cgaccggatg tggcgctcac gtcgcatccg gtcgggtgtg ccagtgtctg
    16861 cactgaattg cctgatgcga cgctatcgcg tcttatcatg cctacgttat aaaactatcg
    16921 atgtctgtcg cgtcttatca tgccaccatt ataaaattat cgctgttttg cggtacgcta
    16981 tcgccaggtt atgccagaat cataaaaaag caggttggga gtcgtcaggg tgcagcacga
    17041 gacaaaaatg gaaaaccaga gctggttgaa aaaactcgca cgccgcctgg ggcctggtca
    17101 tgtcgttaat ctctgcttta tcgtggtatt gcttttttcc accttgctca cctggcgtga
    17161 agtagtggtg ctggaagatg cctatatctc cagccagcgt aatcatctgg aaaacgtagc
    17221 caacgcgctc gataagcatt tgcagtataa cgtcgacaaa ctgatctttt tgcgtaatgg
    17281 catgcgcgaa gctctcgtag cgccactgga tttcacttca ctgcgtaatg ctgtaaccga
    17341 gttcgaacag catcgcgacg agcacgccta gcaaattgaa ctcaaccgac gacgcaccct
    17401 gtcagtcaat ggcgtatcgg atgcattagt cagcgagggg aatctcctgt ctcgcgaaaa
    17461 tgaaagcctc gacaatgaaa ttaccgctgc actggaagtt ggttacttgc tgcgactggc
    17521 gcacaacacc tcgtcgatgg ttgaacaggc gatgtatgtc tcgcgtgccg gattttacgt
    17581 ttcgacgcag ccgaccttgt ttacgcgcaa tgtaccaacg cgttattacg gctatgtcac
    17641 ccaaccctgg tttatcggcc attcgcaacg agaaaatcgt caccgcgcgg tacgctggtt
    17701 tacttcgcaa ccggaacacg ccagcaatac tgaaccgcag gttaccgtca gtgttccagt
    17761 agacagtaat aactactggt atggcgtgct ggggatgagt attcccgtgc gtaccatgca
    17821 gcaattttta agaaacgcca tcgataaaaa cctcgatggt gagtatcagc tctatgacag
    17881 taagctgaga tttttgacct cttccaatcc tgaccatcca acagggaata tttttgatcc
    17941 tcgtgaactg gccttgctgg cgcaggcgat ggaacatgac acgcggggcg gcattcgtat
    18001 ggacagtcgc tatgttagct gggaacgtct ggaccatttc gacggtgtgc tggtgcgcgt
    18061 ccatacgcta agcgaaggcg tgcgcggcga tttcggcagt atcagcattg cattaaccct
    18121 gctgtgggcg ctctttacca ccatgttact catctcctgg tatgtgattc gccggatggt
    18181 tagcaacatg tatgttctgc aaagctcgtt gcagtggcag gcgtggcacg acaccttaac
    18241 ccgtttatat aatcgtggcg cactgtttga aaaagcccgt ccgctcgcga aattgtgtca
    18301 gacgcaccaa catccttttt ctgtcattca ggtcgacctt gaccatttta aagcgattaa
    18361 tgaccgcttt ggtcatcagg cgggcgaccg tgttctttct catgctgccg gattaattag
    18421 cagttccttg cgtgcgcagg acgttgccgg gcgggtcggt ggtgaggagt tttgtgtgat
    18481 tctgccaggc gcgagtctga cggaggctgc ggcagtcgca gaacgtattc gcctgaagtt
    18541 gaatgaaaaa gagatgttga tcgctaagag tacgacgata cgcatcagtg cctcgctggg
    18601 ggtaagcagc agcgaggaaa ccggtgatta tgattttgaa caactccagt cactggctga
    18661 ccgtcggctt tatctcgcta aacaggccgg gcgtaatcgg gtatgcgcga gcgataacgc
    18721 ttaacgggcg gagaaaaaat ggtccagccc ttcacgccag ccttccggtc cttcacgctg
    18781 cgttcgccag acgcgggccg gatcctcatc atgcagatgc accccttcac ggtttagccc
    18841 tttcacaatc accgcgtaat ccattacctc cagtaagggc gcatcgtttg gcccatcgcc
    18901 caggccaagt gtggttgggc gtttgcctga caattgttga taagtcgcga taatccagtt
    18961 ggcagcctga tcttttccgg cagaggcatc cagtacatgc cagaagcgcg caccctgcat
    19021 aaactgtaag cccagttcgt tcagacgcgc ggtaaattgt gccatacgct cgtcactgtc
    19081 gcgccagatt agcgttaccg acgcctcatg aagctgcgtc agcgccgcct ggctacggct
    19141 taatcccgtc cattcggcga tggttgcatc gtcgacatca tcaaaagttg tgaatttaaa
    19201 atgttctttc tcgcgtagcg tatttaaaac ctggctgatt tcgccatggc taatacctga
    19261 gatgatgcgt ggaaaaccgt ctatctcctg ccattgttca gcaagctgga tcactgcgcc
    19321 attctctgca atcagcggta agccttgtaa ccccaacatt ttttgcaagt acagcatttc
    19381 tgctgaagtt ttactactac acagaatgac gggtacattt gcttcgcgta aacgggtgag
    19441 ccagggggct gccggttgcc agtcataact atgactatcc agcagggtgc catcaagatc
    19501 gctaaaaacc agtagtggtt gttgaattga aaacatagtc gcgcagtact ccccttacca
    19561 ggatgattct caaaacagca caaattatca aagatgattt tttcgggagc gatcccgctg
    19621 acgccagagc caccaagggg tgacgtgcgt cacatttcta ttcataagta gcgttaatca
    19681 ttcatatggc gaatattttc ttgtcagcga aaaaaattgc ggataaggtg atgaacacat
    19741 cagatttcct ggtgtaacga attttttaag tgcttcttgc ttaagcaagt ttcatcccga
    19801 ccccctcagg gtcgggattt ttttattgtg cattcaacga ttcacttcag agacgctgaa
    19861 gtcatgaata tccagttcga aggcatccgc caattcacgc catgtatgat attcacgtcc
    19921 atcgacgcta acgtgttcag aatcgttctg gctgcgatga acttcgcttt cgctaatttc
    19981 attgatcgcc gccagcaggg catcgacatc gacgctgacc tcacgttttg cggtatcgct
    20041 gtactctttt gcggttttca tcatctttcc tcgcaaccgt tactctgttg ttgccgccag
    20101 tcgttaagtc cgcctggcat ctcttaagta tagaccgtcg agaaaatcag cactcgcgcg
    20161 cggctggcgc tgccagaaaa acgaaattgt tctacactgg cacaaagcca caggaggaaa
    20221 acgatgaagg tgaatgatcg ggtaacagtc aaaacggatg gcggtccgcg tcgtcctggc
    20281 gtggtactgg cagttgagga gtttagtgaa ggcacaatgt acctggtttc gctggaagac
    20341 tacccgctcg gcatctggtt ctttaatgaa gcagggcatc aggacggtat ctttgtggag
    20401 aaagcagagt aatcttattc agcctgactg gtgggaaacc accagtcaga atgtgttagc
    20461 gcatgttgac aaaaatacca ttagtcacat tatccgtcag tcggacgaca tggtagataa
    20521 cctgtttatt atgcgttttg atcttacgtt taatattacc tttatgcgat gaaacggtct
    20581 tggctttgat attcatttgg tcagagattt gaatggttcc ctgacctgcc atccacattc
    20641 gcaacatact cgattcggtt cggctcaatg ataacgtcgg catatttaaa aacgaggtta
    20701 tcgttgtctc ttttttcaga atatcgccaa ggatatcgtc gagagattcc ggtttaatcg
    20761 atttagaact gatcaataaa ttttttctga ccaatagata ttcatcaaaa tgaacattgg
    20821 caattgccat aaaaacgata aataacgtat tgggatgttg attaatgatg tgctgactgt
    20881 tagaagcatc atggatgaaa cagtcctcat taataaacac cactgaaggg cgctgtgaat
    20941 cacaagctat ggcaaggtca tcaacggttt caatgtcgtt gatttctctt tttttaaccc
    21001 ctctactcaa cagatacccg gttaaaccta gtcgggtgta actacataaa tccataataa
    21061 tcgttgacat ggcataccct cactcaatgc gtaacgataa ttccccttac ctgaatattt
    21121 catcatgact aaacggaaca acatgggtca cctaatgcgc cactctcgcg atttttcagg
    21181 cggacttact atcccgtaaa gtgttgtata atttgcctgg aattgtctta aagtaaagta
    21241 aatgttgcga tatgtgagtg agcttaaaac aaatatttcg ccgcaggagt atcctggaag
    21301 atgttcgtag gtattatttt tcggataatc cttaggataa catgataaac gttacggaat
    21361 tatattaatg gcaattcact aataatatca gccagcaaat taaaaatttc actgaataaa
    21421 tgttcgcaaa aagacgcaat taacggcatt aatgccgcca ttaaagagat accgacagtc
    21481 agagttaatg gaaatccaat aacaaaaatg gataattgcg gggccatacg attcagtaaa
    21541 cctaatgcca gattcagggt cagcagcaga gtaatgagcg gtaacgccag catcagcccg
    21601 ttaaggaaaa tcaaactccc tgctttggtg agtgccagaa acgcattgct gttcaacggt
    21661 tcgccaccaa ttggcagggt gtgaaaggta tcgaccagca gtgaaattaa ccataaatga
    21721 ccgttaaatg tcaggaacag caataacgcc agcatatcca tgatacgcgc taaaacgggc
    21781 atattgagat ggctggccgg atcgacaaac gtcgcaaatg acagccccat ttgcaggccg
    21841 ataatttcgc cagcggttcg cacagcggca aaggcaaatt gcatggtaaa accaagcgca
    21901 atgccgatca ggatctgctg cacggccagc cacagagcaa agaacgaaaa aacaggaaca
    21961 tcgttggcag gtaatgatgg ggcaattgcg aacgtgatca tcattgccag acccagtttt
    22021 acccgtttcg gcacgctgcg ttcgctcaca attggcgcgg tagaaatgag cgccagcacg
    22081 cgcagtaacg gccagaagta gaggcttaac caggatagcc attgttcgct tgtcacctgc
    22141 aacatagtac ggctacccga tgatatacgg caggttagtg aacaaggtgc ggacgtaatc
    22201 cagcaacaga ttgagcatcc acggtccggc aataataatg gcaataaata cggcgatgat
    22261 ttttggaata aacgacagcg tcatttcgtt gatctgggtg gcggcctgca aaatactgat
    22321 gataaggccc gtgaccagcg ccaccagcaa cagcggggca gccagtgcca gcgcgacttt
    22381 catcgcttca gtccccatca tcatgaccga ttcaggtgtc attttgcctc tctagctgta
    22441 aaagctctgc gccagcgaac cgaccagcaa ttgccagcca tccaccagta caaacagcat
    22501 cagtttaaag ggcagagcaa tggtggcggg ggggaccatc atcatcccca atgccatcaa
    22561 cacgctggca atcaccaggt cgataatcaa aaaagggatg aaaatcgtga agcctatctg
    22621 aaatgcggtt ttcaactcgc tggtcacgta ggccgggagc aaaatgcgca tcggcacggc
    22681 ttcaggtccc tgcaacggac cagtattcgc cagtctggca aacaccccta aatccgcctc
    22741 acgggtctga tgcagcataa actcacgcag cggctgcgcc cctttttcca gcgcctcctg
    22801 cattgatatt ttctcttcgc tgaatggctg gtacgcatcg acataaattt tgtcgatcac
    22861 cggtgacata ataaaaaagg tcaaaaatag tgccagcccc agcaatacct ggttaggtgg
    22921 cgcggagggc gttcccagcg cgttacgcaa taaaccaaaa acaatgatga tgcgggtgaa
    22981 actggtcatc atcagtaaaa ttgccggaat aaacgtcaac gaggtgatga acaccagcgt
    23041 ctgcaccggg agcgaccagc tttgtccacc gccaggcagc ggctggctgg tgatacccgg
    23101 cagttgcgcg aaggcgaggg gcgtaaccag ccagagaagg acaggtgcga cagacaacaa
    23161 acgacgcatc aggatctccc actacgctta agcaaatttt tcatgaccga ctgaaaatcg
    23221 gtctgcggta tctcttctgt tggtgctgaa gggggaagtt tatgcagcag attgatttgc
    23281 cctgcggtaa cgccgagcac cagccgtgca tcttccacat cgaccaccac aacccgttca
    23341 cgcgcgccca gcgaagcact ggcgctaatt ttcagaccgt taacgccagt gcgtttcggg
    23401 gcaaatccca accgttttac cagccaggca gcagcgagga tcagggcaat aatggcgatg
    23461 agtgcgccgc tgacctgcag cagtggcgca gcagaaaccg gcgtggaaga ttgcacagta
    23521 gcgtggttat tcatcactaa cggctcaggc gacgcattcg ctcagacgga gtaatgatat
    23581 cggtgatccg cacgccatat ttatcggcaa tgaccaccac ttcgccctgg gcgattaaat
    23641 aaccgttgat cagaatatcc agtggttcgc ccgccagacc gtccagcgcc acgacggacc
    23701 cttgcgtcag acgcaacagc tctttgatgg tcatccgcgt acggcccagc tcgacggtca
    23761 gcttgaccgg aatatccatt atcaggtcga tatcctgcaa cgttccgctg acatcaccac
    23821 cgccaaattg ctggaacacc gcgtcggcag cgcttttgct gctggttgat ttttgttcgc
    23881 tcaacgcttc agcccacaga tcgtccattg cgccgttgtt gtcatcggcc ggattattca
    23941 tgtcactcat ttgggctgtt cctcgttcag agaatttaaa atcgggttaa tcaaatgttc
    24001 tatccgtaac gcatactgac cgttgagagt gccgtactga ctggtcagca ccgggacgcc
    24061 gtcaacatgg gcgatgatgc gatcgggttt ttctatcggc aggacgtcgc cgggtttcag
    24121 ttttaaaatc tgcgacaggc gtagcgagat atcggcaaag ttggcgacca gctccagctg
    24181 tgaatgctgc acctggcgca ccaggttatc gcgccagttc tgatcttcat tacgcgagtt
    24241 ttccagcggc gggttaacca acaattcccg tagcggctcg atcatgctga atggcagaca
    24301 gatattaaat tcgccggtca ggttgccaat ctccacatgg aacggcgtgt taaccacaat
    24361 gtcgttcggc gaggtggtga tattggtaaa tttcacctgc atttccgaac gcacgtactc
    24421 aacttccagc ggattaatcg ccttccaggc gtcgctatag ccttcaagcg ccagctttaa
    24481 catgcggttg atgacgcgct gttcggtatg ggtaaactcg cgaccttcca ctttggtcgg
    24541 gaagcgtcca tcgccgccaa acaggttatc cacggcgata aacaccagac tcggtgaaaa
    24601 caccaccagc cctgtgccgc gcagcggttt cagatggata aggttcaggt tggtcggcac
    24661 cggcaggttg cgggcaaatt catggtacgg ctgaatgcgg atggccccga cggttatatc
    24721 tgggctacgg cgcagcaggt tgaacagccc catacgaaaa tggcgggcaa agcgctcatt
    24781 aatgatttcc agcgcctgca aacgttcgcg cacaacccgt cgttgggtat tcggatcgta
    24841 cggacgaatg tcactttcgc cgctaacact ggctgtcggt tcgtctttga cttcgctgtc
    24901 accattcaac agcgcatcaa tttcagcttg agaaagaata ctatcgccca tgtcgttatc
    24961 gcagaataaa agcggtatac agcacgtcgg tgacatcctg tttcggttgc ccggcaacaa
    25021 gcggggtgga aagcgtggtt ttaatctcgg taatcaggtt tttcttgcct tcttctgtcg
    25081 ccagtacggc agcatcctga cgcgaaaaca gtaacagcaa acggctacgg acttccggca
    25141 aatactcact cagccgcgag cgtgtagctt catctttcag gcgcagggtt atgccgatat
    25201 acagcacgcg atccgcatcg cccagattga ccgtaaaggt atccagcgca tagaagaccg
    25261 gggagggcac gacgcgttgc tgcgctttgt cgtcagcggc aacctgatgc gaatgccagt
    25321 agctgtaacc tgcgctggca caggccgcga gggtaatgaa taccagaatc gggatccaaa
    25381 gcgatcgctt gcttttcttg cttatcgcgt aatcagtcat gtgttgcggt cttcctgtgt
    25441 cgctactgct tatcggctaa ttatcctgcg tcttgagcgc aacaaagcgg ggaaaagacg
    25501 cggattacgg tgctacctct gacgttaggc gaaaatatca acgccgctgt tgcctgttac
    25561 gcgcccttgt aaagagacgg gaaccggaag cgtatcgtct tcttcccccg ccagaggttc
    25621 atggtttact gtgcgttggc tttgctgttg ttgggaagcg gcctgctgct gaccactaaa
    25681 gctttcgcca ctgatgttgc tttgccctaa ctgaatgcca ctttcggcca gctgcgtacg
    25741 cagtaccggc agcgctgctt ccagggcggc gcgtacatgc tgatgcggtg aaaccatctg
    25801 gatttgcgcc tggttatcat ccactttgag ggagatttgc acctcaccta aatcctgcgg
    25861 gtgcagacgc aactctgcac tttgttgccc ctggcgggtg aacagcgaaa tatgctggct
    25921 taatgattgt tgccattcgt gagaacccag cggtgcactc aaaacaggcg cggcgacggt
    25981 gggcagtggc tgtgtctggt gtggagtgat tagcgggctg gcggcagcgg tcaccggcga
    26041 aggcgtgctg atgatttccg ctttactctg ggcttctgct atcagcggtg ttaatggctg
    26101 agctggcgtg ccgggggcgt catcaggctg tgctgttgtg agttgcgcag aagtcagttt
    26161 tgtgaagagc gttggtttct ctgtcggtaa tacggttgac ggtgcatcag tcactttggg
    26221 cgtattgtca aaacccggca acatcgcaaa aagggcactc aggctggcgg tgacgtcttc
    26281 attcagatca tccgcttttt cgtcttttgc cgtattgttg tcagccgccg cagccaacgt
    26341 tatcgtctga gcggtgttta acggtgttga tgtggattgt tcgtcgttga tgacaggcgg
    26401 tgtttcatcc acagggatca gtaaatccgc ttgttgcgcg tcggaaacaa tatcgctgac
    26461 cagcggctcg ccttttgtcg tgggcttatc tgttgccacc agcaactggg gagtcgcttt
    26521 gtcggttgtt gcctcgcctg ttaatgcttc gctcaacaac gcgagaaaat cttgtgcagc
    26581 atcgctggct ttgccgccag acaatgtggt ggtgtcaacg tcggcggtaa tcaagggcgc
    26641 taagcgaatc attcaggttt cctcatggcg gcgcgctggg cgaactcatc catctttttc
    26701 tgatcgaggc ggttttctgc aagcagtgcc gccgtggatt gccgttcctg cagtgtctgc
    26761 caggcctgca aacgttgttt cttttctcgc cagctgttca gggcaatgtc aactttctgc
    26821 gtccactgat taagttgctg gcgatgctga gtaatggctt tttccagcgt ctggataaac
    26881 tgctgatagt tgatccagcg gttgctggtc atcccggcac tcatatcgct attgaggtta
    26941 ttgcgatatt cattctgata atcgatcagc attttgagct gttcttccgc ctgctgacat
    27001 ccgcgacgca tttcacccag caggcgagcg gcatcctcta cctctttttc tgccagatct
    27061 ttcagggtcg ccagcgcacc atgttccgcc atctgccgtt atctcctggg ttatgacact
    27121 gtcgggaaaa tacgctccag cccctggaga gacgcttccc agtccgcgcg ttcaaaaatg
    27181 ccttgttgca aatagccctc cagctgcggc cacagggcga tggctttatc gagcatcgga
    27241 tcgctgcctt tggcatacgc gccgacgcta accagatcgc ggttacgctg aaaactcgac
    27301 aacagctgtt tgaaggtgcg cactcgcgcg taatgttgct cactgatcaa cgccgtcatt
    27361 gcgcgactga tcgacgcttc aatatcgata gccggatagt gcccggcttc cgccagtcgg
    27421 cgagacagca caatgtggcc gtcgaggatg gcccgcgcgg agtcggcaat ggggtcctgc
    27481 tggtcatcgc cttcggtgag cacggtataa aacgcggtaa tcgagccgcc gccgctaatg
    27541 ccatttccgg cacgctcgac cagtgccggt aatttggcaa acaccgacgg tggataacct
    27601 ttagtggcag gtggttcgcc aatcgccagc gcaatctcac gctgggccat cgcgtagcgg
    27661 gtgagggagt ccataatcag caatacatgc tgaccacgat cgcgaaaatc ttcggcaatt
    27721 cgcgtggcat aggcggcacc ttgcattcgc agaagcggag aaacatccgc cggagcggca
    27781 atcaccacgg agcgtgcacg cccttcggca ccgaggatat tctcaataaa atcttttact
    27841 tcgcgtccgc gttcaccaat caaacccacg acaatgacat cggcgcgggt gtaacgggcc
    27901 atcatcccca gcagcacact tttaccaacg ccggacccgg caaacagccc catacgctgc
    27961 ccgcgcccga cggtaagcag ggcattgatt gggcgcacgc cggtgtccag cacatgttca
    28021 atcggtgtac gttgcaatgg gttaaatggc ggggtaatca gcgcaccggt ttccgtcgta
    28081 tcgggggagg ggaggccatc gagcggttta ccgctgccgt ccagaacgcg acctaataac
    28141 gccggaccga gcggcaactg cttgccgctt tgcagccctt cagccgaaat gtttttggca
    28201 taaacacgcg cgccgggcag gacaccttcc acttcctcca gcggcattaa aaacagccgt
    28261 tgaccgttaa agccaacgac ttcgctttct acttcgtgcg tttcgctgcc gttctggcgc
    28321 tcaatcacac aggttgcgcc gagcggcaat tgtaatccgg tggcttccag caccagcccg
    28381 gtagcgcgag ttaatcgccc gtagcgacgt accgcaggca actgcgccat tttagcttcg
    28441 aagttatcca gcgtggttag ccagcgagtc aggcgcgtgg tcattacacc actcctggtg
    28501 ctgccagacg gcagagttct tgccagcgag tggcgacact ggcgtcgaga tcgccttcat
    28561 cggcggagac tttacagccg ccaggatgga gggtgggatc gccccgcaag cgccagccat
    28621 gcaaacttaa agttgcgccg agcatatcat ccacacgttg cagatcatcc gggtgcacgc
    28681 gcagctgcgg tttgccgctg aacaacggtt cttgctgcaa caacagttgg atctgtttga
    28741 tcagtgccga gttatccacc gttggcgtct gaccgatcac ctgacgtgct gcctccagcg
    28801 ccatctgcat caggcgcgaa gcaatcacac tatcaagcgc atcaagggta gtttgaaatt
    28861 cgctgaccag ttgctgcatc cgggcatgaa ttggcgcttg ttgagccttc gcctctgcca
    28921 gaccttgttc cagcccctgg gccagtcctt cctgatagcc ctgttcgtga ccttgctggc
    28981 gaccttcggc aatccccgcc tgataaccct gctcgtgggc ctgcatttgc agttgcgcca
    29041 gttgctgctc aaggctgggt tcggcctctt caatgatggt ttcttccggt tcgactattg
    29101 gcacaaactc tgccggtggt ggcgcaagat cgtccggcat ccaggttttc cacggcagat
    29161 tatcagacat aggtatcctc gccgctgcca atcaccatct cgccggtttc ggcaagacgg
    29221 cgcacaatca gcagaatcgc tttctgttcg ttttccacct gcgacagacg caccggacca
    29281 cggttggcga gatcgtcgcg cagaatatcg gcggcacgtt gcgacatatt gcgcaggaat
    29341 ttctcgcgca gtggctgctc ggcccctttc agcgcgatca gcaacgattc ggaatccact
    29401 tcctgcaaca gacgctgaat gctgcgatcg tcgacatcca ccagattctc gaacaggaac
    29461 atctcgtcga taattttttg cgccagttcg ccgtcgaatt cacgcacggc ggtaataacg
    29521 gcttcttcct gctgagtttt catcaggttg ataatttcgg ctgccgttct cacgccgccc
    29581 attttgctgc gcttgagatt ctgaccgtcg agcaagccat tcagtacttc ggtcagttcc
    29641 gccagcgcgg ctggctgcac gccgccaaag gtggcgatac gcaacatcac gtcgtggcgc
    29701 agacgttcat cgaacaacgc cagaatatcg gcggcctggg cgcgcttcag atgcaccaga
    29761 atggtggcga taatttgcgg atgctcatcg cgaatcagat cggcggcact ctgcggctcc
    29821 ataaagttga gcgtttcaat accgctggcg gtatcgcgag tttcgagaat atcttccagc
    29881 aggctggcgg cacgttcctc acccagagct ttgaccaata ccgaacgcag ataatcgttg
    29941 gcgttgatat tcagtgcggc aaactgttca gcttcttgct caaactccgc cagcacatcg
    30001 gttagctgct tgttggagat ctgcgtgacg ttcgccattg cagcgctcag ggtttgcact
    30061 tcgcgctggg agaggtgctt gaacacctct gccgcccggt cttcgccaat ggtcatcagc
    30121 aggatgacgc ttttatcggt gcctgtcagg ttactcatga tcgttattta tccactggcg
    30181 aatgaccagc gccaccacgc gcggatcgtt atcagacatt tcacggatac gctggctcat
    30241 gacttctgcc cccagacgtt ggttagcgcg tcgttgttgg agttgttcgt ctttgctcag
    30301 gcggacttcc accgcatctt ccacttcctc acgggcctgc gcctgttgct gtacagcttt
    30361 catcgcctcg gcgcgacgtg ttaactgcgg gcgtaccgct ttccgccaca gcagccacgc
    30421 caccagcagt accagcaacc agcgaccggc agccagcaac tgatcgataa acgcttgctg
    30481 ttgccagaac ggcagttctc cgccgccttc gtcactgcta ttgaacggcg agttaacgac
    30541 attgagcgag tcgccgcgtt tttcagaaaa gcccatcgcc tcgcgggtca gatcttcaat
    30601 ttgcttcatc tgttcgttgc tgagaggcaa tggtttaccg tctggcaagg ttttgtaatt
    30661 caccactacc gcgactgaca gacgttgcac atcgcccacg ttcattttgg tatgacgaat
    30721 ggtgcgatcg acttcgtagt tactggtttc attccgctgt gtgctacgcg gcccgctatt
    30781 gctggtggtg ctcgcctgct gctggcggtt attttgattt gccggaggcg tgctgattgg
    30841 cgcgttattc gcaggtgccg gttgattcga caacgccccc ggtacgccgc ccggataacc
    30901 ggaaccgctt tgctcgctct cattaagctg gcgtgaacga agcgccgcat gagattcatc
    30961 accgttaggg cgatactgtt cttccgtttg ttctttactg gcgaagtcca gctgcgccgt
    31021 gacctgggcg tgaatattac cgttaccaac aataggcgac aggattgctt caatacgccg
    31081 ctgaatacgg ccttcgacat cgctggcata tttcaactga gcatcattaa gatcgcgccc
    31141 gctggtattg gactgggtta acagatgtcc gccctgatcc accagcgtga cgtttcccgg
    31201 cggcagacca gcaacggcgc tggaaaccag atgcacaatg gcgctaattt gcccttcatc
    31261 gagtgcgcgg ccgggtaaca gatttaccgt caccgatgca gaaggggatt tttgttcacg
    31321 gacgaataaa gacggtttcg gcattgccag atgtacgcgc gcccctttta ccgggccgat
    31381 agtttcgatg gtacgagaaa gctcgccttc cagcgcccgc tgataattca cctgttcgct
    31441 gaactggctg ataccaaact tttcctgatc gagtagttcg aaaccgaccg cgccgccttt
    31501 gggcaaacct tgttgcgcca ggcgcagacg cagctcgtga actttatctg ccggaacttc
    31561 aatagcgccg ctggcttcgc tgaagcggta aggaatattc atttgcgtca gttggctgac
    31621 aattgcgcca ccatcctgat cggaaagatt gctgaataat gtgcggtagt cgggggcttt
    31681 cgcccacagg atcagtgcga ccatgaccgc cactgccgcg gaaccggcaa caatcaatgg
    31741 aattttcgga ttcgcacgca ggcgattaag ccactcaaga gattttgtct gggctgcagt
    31801 cgcattcatc gcgcacctcg tggctgatta tggacggcgt tattggcaaa gtggaacaag
    31861 actcactccc gggtcagcaa actcgaaaaa ttgacgctgc cattatttgt gctttcgttt
    31921 ttttctatcc gccaataaac ccgttttttt gttgctattt agcgcctttg tcttattgac
    31981 ttactggtag gctttgctac cagaaattat ccaggagacg aaaatgtcag cgatacaggg
    32041 gattgaaggg gttatcagcc agttacaggc tacggcgatg agtgcgcgtg cgcaggattc
    32101 actgccgcaa ccgaccatta gttttgccgg gcagctgcac gccgcgctcg atcgcattag
    32161 cgatacacaa acagctgccc gcacgcaggc agaaaaattc accctcggtg aacccggcgt
    32221 ggcgttaaac gatgtgatga ccgatatgca aaaagcctca gtttctatgc aaatggggat
    32281 tcaggtgcgt aataagctgg tggcggcgta tcaggaagtg atgtccatgc aggtgtaggt
    32341 tttgtaacct gttgactatg cttgtttatt atatccgatc ccacagcgtg gggcatggat
    32401 ggggcaaact cactcaattt ctggtttaaa atggatacct gatcctgaaa gttttctgcc
    32461 atccacgatc cgtaaacgcg ataacatgtt ttgtcttcgc tttgctccca ggaagagtga
    32521 actcattcgt tagcctgggg ttccttctga tcattattgt tcctgccttt atctcttgcc
    32581 acgccagagc cccctggata cacatacact aggatgaaaa cggtgagttg tgttcaaact
    32641 gtagtacaat tctctccagt atgaacagga aagaatatgc tatgaaccct tatatttatc
    32701 ttggtggcgc aatacttgca gaggtcattg gtacaacctt aatgaagttt tcagaggggt
    32761 ttacacggtt atggccctct gttggcacaa ttatttgcta ttgtgcatca ttctggttat
    32821 tagctcagac gctggcttat atacctacag ggattgctta tgctatctgg tcaggcgtcg
    32881 gtatcgttct gattagtttg ctttcctggg gattttttgg tcaacgactg gacctgccag
    32941 ctatcatagg catgatgttg atttgtgccg gtgtgttagt cattaacttg ttgtcacgaa
    33001 gtgcaccgca ttaaaaaata attatccttg agataacagg aatctgattt gtgcatatta
    33061 tggctaatgt tcggggcacc tttataatta tgattgcatt tgcgcgatca ttgcgccttt
    33121 atgcataatg agatcaaggc acatcaaata aaataacgat aggtcacaac aatgaggttt
    33181 ttatgaaaaa acttatcgtt tcaagtgtat tggcattcat aacattttct gcgcaggccg
    33241 cagcatttca ggtcactagt aatgaaataa aaacaggaga gcaacttaca acgtctcatg
    33301 tattttctgg atttgggtgt gaaggtggta atacatcgcc ctcattaacc tggtctggtg
    33361 ctcctgaagg caccaaaagc tttgccgtaa ctgtgtatga tccagatgct cctacaggca
    33421 gtggatggtg gcactggact gttgctaata ttccagcaac tgtaacatat ttgcccgctg
    33481 atgcaggaag acgtgatggt acaaaacttc cgactggtgc tgttcaaggc cgaaatgatt
    33541 ttggttatgc aggatttggt ggagcatgtc ctcccaaagg agataaaccc catcattacc
    33601 agtttaaagt atgggctcta aaaactgata aaattcctgt ggattctaat tccagcggag
    33661 cgttagttgg ttatatgctt aatgccaata aaattgcaac cgctgagata acaccagttt
    33721 atgagataaa gtagggtaag agtatgctgg caaaagataa gactaaccta aagattgaag
    33781 aaatacggat gcataaacat catgagattc acagggttaa gcctcttatg ccagctttat
    33841 gtcgtatccg tcagggaaaa aaagttatca attgggagac gcatagtcta actgttgata
    33901 ataatcagat aatattattt ccctgtggat atgaatttta tattgcgaat tatccagaag
    33961 caggtcttta tcttgcagaa atgctttatt atcccattga tctaattgaa aagtttcaaa
    34021 aattttatgc gataactgat caaattcgta acacgacagg tttctgctta cctcagaacc
    34081 ccgagttaat atattgttgg gagcaactaa aaacatctat ttcccgaggc ttctcaacgc
    34141 aaattcagga acacttagca atgggcgttc tactttcatt aggagcacat catgttaatt
    34201 gtttactttt atcagatagt aaacaatcat taataagtcg ttgttataac ctaatgctat
    34261 ccgaacctgg aacaaaatgg acagcaaaca aggtagcgag atatctctac atttctgttt
    34321 ccacattgca tcgccgtctg gcaagcgagg gagtaagttt tcaaagtata ttggacgacg
    34381 tgaggttaaa taatgcgttg tctgctatac aaacgacagt aaaacccatc agcgagattg
    34441 ccagggaaaa tggttacaag tgtccttctc gttttactga aaggttccat aatcgtttta
    34501 agataacacc aagagagcta agaaaagcgt ccagagagta aaagtatttt atgaaggagc
    34561 aacagcatcg atttttattt tggaaaataa atacggcata ctcaacctat tggagtctga
    34621 acaatccggt gacttctgcg ctaatcgggg acgtttctaa gcacatataa ttgatactat
    34681 cttcctccat cacaatttca gaaatgcacg tgtgattttt ttgcatccgg cgtttggact
    34741 atgtggagct caagagtggg aaagttacaa gaggttgagg ggataattaa agggatgctt
    34801 atgacattag atatccggtt aggtactaga ctggccccct gaatctccag acaacca
//
LOCUS       DADXDL010000052        34757 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.052, whole genome shotgun sequence.
ACCESSION   DADXDL010000052 DADXDL010000000
VERSION     DADXDL010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34757)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34757)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34757
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.052"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(175..1863)
                     /gene="betA"
                     /locus_tag="IRB70_002793"
     CDS             complement(175..1863)
                     /gene="betA"
                     /locus_tag="IRB70_002793"
                     /EC_number="1.1.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline dehydrogenase"
                     /protein_id="HBC0632683.1"
                     /translation="MQFDYIIIGAGSAGNVLATRLTEDPNITVLLLEAGGPDYRFDFR
                     TQMPAALAFPLQGKRYNWAYETEPEPFMNNRRMECGRGKGLGGSSLINGMCYIRGNAL
                     DLDNWAQEPGLENWSYLDCLPYYRKAETRDVGENDYHGGDGPVSVTTSKPGVNPLFEA
                     MIEAGVQAGYPRTDDLNGYQQEGFGPMDRTVTPHGRRASTARGYLDQAKSRPNLTIRT
                     HAMTDHIIFDGKRAVGVEWLEGDSTIPTRAAANKEVLLCAGAIASPQILQRSGVGNAE
                     LLAEFDIPLVHELPGVGENLQDHLEMYLQYECKEPVSLYPALQWWNQPKIGAEWLFGG
                     TGIGASNHFEAGGFIRSREEFAWPNIQYHFLPVAINYNGSNAVKEHGFQCHVGSMRSP
                     SRGHVRIKSRAPHQHPAILFNYMSHEQDWQEFRDAIRITREIMHQPALDQYRGREISP
                     GVECQTDEQLDEFVRNHAETAFHPCGTCKMGYDEMAVVDGEGRVHGLEGLRVVDASIM
                     PQIITGNLNATTIMIGEKIADMIRGKDALPRSTAGYYVANGMPVRAKKMSRDVN"
     gene            complement(1877..3349)
                     /gene="betB"
                     /locus_tag="IRB70_002794"
     CDS             complement(1877..3349)
                     /gene="betB"
                     /locus_tag="IRB70_002794"
                     /EC_number="1.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine-aldehyde dehydrogenase"
                     /protein_id="HBC0632684.1"
                     /translation="MSRMAEQQLYIHGGYTSATSGRTFETINPANGNVLATVQAAGRE
                     DVDRAVKSAQQGQKIWAAMTAMERSRILRRAVDILRERNDELAKLETLDTGKAYSETS
                     TVDIVTGADVLEYYAGLIPALEGSQIPLRETSFVYTRREPLGVVAGIGAWNYPIQIAL
                     WKSAPALAAGNAMIFKPSEVTPLTALKLADIYSEAGLPDGVFNVLPGVGAETGQYLTE
                     HPGIAKVSFTGGVASGKKVMANSAASSLKEVTMELGGKSPLIVFDDADLDLAADIAMM
                     ANFFSSGQVCTNGTRVFVPTKCKAAFEQKILARVERIRAGDVFDPQTNFGPLVSFPHR
                     DNVLRYIAKGKEEGARVLCGGDVLKGDGFDNGAWVAPTVFTDCRDEMTIVREEIFGPV
                     MSILTYESEDEVIRRANDTDYGLAAGIVTADLNRAHRVIHQLEAGICWINTWGESPAE
                     MPVGGYKHSGIGRENGVMTLQSYTQVKSIQVEMAKFQSIF"
     gene            complement(3363..3950)
                     /gene="betI"
                     /locus_tag="IRB70_002795"
     CDS             complement(3363..3950)
                     /gene="betI"
                     /locus_tag="IRB70_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308386.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator BetI"
                     /protein_id="HBC0632685.1"
                     /translation="MPKLGMQSIRRRQLIDATLEAINEVGMHDATIAQIARRAGVSTG
                     IISHYFRDKNGLLEATMRDITSQLRDAVLNRLHALTDGSPEQRLQAIVDGNFDETQVS
                     NAAMKAWLAFWASSMHQPMLYRLQQVSSRRLLSNLVSEFHRELPRHQAQEAGYGLAAL
                     IDGLWLRAALSGKPLDKPLAHSLTRHFITQHLPTD"
     gene            4079..6112
                     /gene="betT"
                     /locus_tag="IRB70_002796"
     CDS             4079..6112
                     /gene="betT"
                     /locus_tag="IRB70_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline BCCT transporter BetT"
                     /protein_id="HBC0632686.1"
                     /translation="MTDLSHSREKDKINPVVFYTSAGLILLFSLTTILFRDFSALWIG
                     RTLDWVSKTFGWYYLLAATLYIVFVVCIACSRFGSVKLGPEQSKPEFSLLSWAAMLFA
                     AGIGIDLMFFSVAEPVTQYMQPPEGAGQTIEAARQAMVWTLFHYGLTGWSMYALMGMA
                     LGYFSYRYNLPLTIRSALYPIFGKRINGPIGHSVDIAAVIGTIFGIATTLGIGVVQLN
                     YGLSVLFDIPDSMAAKAALIALSVIIATISVTSGVDKGIRVLSELNVALALGLILFVL
                     FMGDTSFLLNALVLNVGDYVNRFMGMTLNSFAFDRPVEWMNNWTLFFWAWWVAWSPFV
                     GLFLARISRGRTIRQFVLGTLIIPFTFTLLWLSVFGNSALYEIIHGGAAFAEEAMVHP
                     ERGFYSLLAQYPAFTFSASVATITGLLFYVTSADSGALVLGNFTSQLKDINSDAPGWL
                     RVFWSVAIGLLTLGMLMTNGISALQNTTVIMGLPFSFVIFFVMAGLYKSLKVEDYRRE
                     SANRDTAPRPLGLQDRLSWKKRLSRLMNYPGTRYTKQMMETVCYPAMEEVAQELRLRG
                     AYVELKNLPPEEGQQLGHLDLLVHMGEEQNFVYQIWPQQYSVPGFTYRARSGKSTYYR
                     LETFLLEGSQGNDLMDYSKEQVITDILDQYERHLNFIHLHREAPGHSVMFPDA"
     gene            6988..8076
                     /gene="pdeL"
                     /locus_tag="IRB70_002797"
     CDS             6988..8076
                     /gene="pdeL"
                     /locus_tag="IRB70_002797"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator/c-di-GMP
                     phosphodiesterase PdeL"
                     /protein_id="HBC0632687.1"
                     /translation="MNSCDFRVFLQEFGTTVHLSLPGSVSEKERLLLKLLMQGMSVTE
                     ISQYRNRSAKTISHQKKQLFEKLGIQSDITFWRDIFFQYNPEIISATGNNSHKYINDN
                     HYHHIVTPEAISLALENHEFKPWIQPVFCAQTGVLTGCEVLVRWEHPQTGIIPPDQFI
                     PLAESSGLIVIMTRQLMKQTADILMPVKHLLPDNFHIGINVSAGCFLAAGFEKECLNL
                     VKKLGNDKIKLVLELTERNPIPVTPEARAIFDSLHQHNITFALDDFGTGYATYRYLQA
                     FPVDFIKIDKSFVQMASVDEISGHIVDNIVELARKPGLSIVAEGVETQEQADLMIGKG
                     VHFLQGYLYSPPVPGNKFISEWVMKAGG"
     gene            complement(8118..9050)
                     /locus_tag="IRB70_002798"
     CDS             complement(8118..9050)
                     /locus_tag="IRB70_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0632688.1"
                     /translation="MNSIFTEENLLAFTTAARFGSFSKAAEELGLTTSAISYTIKRME
                     TGLDVVLFTRSTRSIELTESGRYFFRKATDLLNDFHAIKRSIDTISQGIEARVRICIN
                     QLLYTPKHTARLLQVLKKQFPTCQITVTTEVYNGVWDAIINNQANIAIGAPDTLLDGG
                     GIDYTEIGAIRWAFAIAPDHPLAFVPEPIAESQLRLYPNIMVEDTAHTINKKVGWLLH
                     GQESILVPDFNTKCQCQILGEGIGFLPDYMVREAMAQSLLVTRQIHNPRQDSRMLLAT
                     QHSATGQVTQWIKKQFAPNGILTGIYQDLLHREN"
     gene            complement(9142..9639)
                     /locus_tag="IRB70_002799"
     CDS             complement(9142..9639)
                     /locus_tag="IRB70_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBC0632689.1"
                     /translation="MNGLTATGVTVGICAGLWQLVSSHVGLSQGWELLGTIGFVAFCS
                     FYAAGGGKSGFIRSLAVNYSGMVWAFFAALAAGWLASVSGLSTFWASVIMTVPFSAVV
                     VWQGRFWLLSFIPGGFLGMTLFFASGMNWTVTLLGFLAGNCVGIISEYGGQKLSEATT
                     KSDGY"
     gene            9897..10502
                     /locus_tag="IRB70_002800"
     CDS             9897..10502
                     /locus_tag="IRB70_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ankyrin repeat domain-containing protein"
                     /protein_id="HBC0632690.1"
                     /translation="MTIKNLPADYLLAAQQGDIDKVKTCLALGVDINTCDRQGKTAIT
                     LASLYQQYACVQALIDAGADINKQDHTCLNPFLISCLTGDLTLLRIILPAKPDLNCVT
                     RFGGVGLTPACEKGHLSIVKELLAHTEINVNQTNHVGWTPLLEAIVLNDGGIKQQAIV
                     QLLLEHGASPHLTDKYGKTPLELARERGFEEIAQLLIAAGA"
     gene            10542..11405
                     /locus_tag="IRB70_002801"
     CDS             10542..11405
                     /locus_tag="IRB70_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HBC0632691.1"
                     /translation="MWSLTADADFLAQRGQGQVEQVFARAVNIALPARQQLLTLLCEE
                     YDNAPNSCRLALTHFNGLFRHGDKVQFDDQGITVGQHLHIEMSHCQRWLSPTLQMTAV
                     NFHLIVWQQWHDIIHQHLGENETLFNYCGDNPFYQALNKELHIKRRAVIQAVNDKQNI
                     ASAVASMMGLGIGLTPSADDYLTGLALILFISGHPAEKYKEEFYLGLQRGRNNTTLLS
                     AITLEAALQQRCRENIHRFIHNIIYDIPGNATQAIEKIKHIGSSSGCDMLYGMADGCA
                     LSQTYGGNYVS"
     gene            11395..12942
                     /gene="fdrA"
                     /locus_tag="IRB70_002802"
     CDS             11395..12942
                     /gene="fdrA"
                     /locus_tag="IRB70_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HBC0632692.1"
                     /translation="MSVKIVIKPNTYFDSVSLMSISTRANKLDGVEQAFVAMATEMNK
                     GVLKNLGLLTPELEQAKNGDLMIVINGKAGADNEQLLVEIEELFNTKAQSGSHEARYA
                     TIASAKKHIPESNLAVISVNGLFAAREARQALQNDLNVMLFSDNVSVEDELALKQLAH
                     EKGLLLMGPDCGTAIINGAALCFGNAVRRGNIGIVGASGTGSQELSVRIHEFGGGVSQ
                     LIGTGGRDLSEKIGGLMMLDAIGMLENDPQTEIIVLISKPPAPAVARKVLERARACRK
                     PVVVCFLGRGETPVDEQGLQFARGSKEAALKAVMLSGVKQEHLDLHTLNQPLIADVRA
                     RLKPQQKYIRGLFCGGTLCDETMFAVMEKHGDVYSNIQPDPEFRLKDINRSVKHTFLD
                     FGDDDFTNGKPHPMIDPTNRISRLIEEARDPEVAVIVMDFVLGFGSHEDPVGSTIEAI
                     KEAKAIAAAEGRELIILAYVLGTDLDTPSLEQQSQMLLDAGVILASSSTNTGLLAREF
                     ICKGEEA"
     gene            12942..14360
                     /locus_tag="IRB70_002803"
     CDS             12942..14360
                     /locus_tag="IRB70_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HBC0632693.1"
                     /translation="MSQSLFSQPLNVINVGIAMFSDDLKKQHVEVTQLDWTPPGQGNM
                     QVVQALDNIADSPLADKIAAANQQALERIIQSHPVLIGFDQAINVVPGMTPKTILHAG
                     PPVTWEKMCGAMKGAVTGALVFEGLAKDLDEAAELAASGEITFSPCHEHDCVGSMAGV
                     TSASMFMHIVKNKTYGNIAYTNMSEQMAKILRMGANDQSVIDRLNWMRDVQGPMLRDA
                     MKIIGEIDLRLMLAQALHMGDECHNRNNAGTTLLIQALTPGIIQAGYSVEQQREVFEF
                     VASSDYFSGPTWMAMCKAAMDAAHGIEYSTVVTTMARNGVEFGLRVSGLPGQWFTGPA
                     QQVIGPMFAGYKPEDSGLDIGDSAITETYGIGGFAMATAPAIVALVGGTVEEAIDFSR
                     QMREITLGENPNVTIPLLGFMGVPSAIDITRVGSSGILPVINTAIAHKDAGVGMIGAG
                     IVHPPFACFEKAILGWCERYGV"
     gene            14456..15406
                     /locus_tag="IRB70_002804"
     CDS             14456..15406
                     /locus_tag="IRB70_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase family protein"
                     /protein_id="HBC0632694.1"
                     /translation="MKELVVVAIGGNSIIKDNASQSIEHQAEAVKAVADTVLEMLASD
                     YDIVLTHGNGPQVGLDLRRAEIAHEREGLPLTPLANCVADTQGGIGYLIQQALNNRLA
                     RHGEKKAVTVVTQVEVDKNDPGFAHPTKPIGAFFSESQRDELQKANPDWRFVEDAGRG
                     YRRVVASPEPKRIVEAPAIKALIQQGFVVIGAGGGGIPVVRTEAGDYQSVDAVIDKDL
                     STALLAREIHADILVITTGVEKVCIHFGKPQQQVLDRVDIATMTRYMQEGHFPPGSML
                     PKIIASLTFLEQGGKEVIITTPECLPAALRGETGTHIIKT"
     gene            15416..16798
                     /locus_tag="IRB70_002805"
     CDS             15416..16798
                     /locus_tag="IRB70_002805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBC0632695.1"
                     /translation="MKENNSRREFLSQSGKMVTAAALFGTSVPLAHAAVSGTTHCEAN
                     NTMKITDPHYYLDNVLLETGFDYENGVAVQTRTAHQTVEIQNGKIVALRENKQHPEAT
                     LPHYDAGGKLMLPTTRDMHIHLDKTFYGGPWRSLNRPAGTTIQDMIKLEQKMLPELQP
                     YTQERAEKLIDLLQSKGTTIARSHCNIEPVSGLKNLQNLQAVLARRQAGFECEIVAFP
                     QHGLLLSKSEPLMREAMQAGAHYVGGLDPTSVDGAMEKSLDTMFQIALDYDKGVDIHL
                     HETTPAGVAAINYMVETVEKTPQLKGKLTISHAFALATLNEQQVDELAHRMAAQQISI
                     ASTVPIGTLHMPLKQLHDKGVKVMTGTDSVIDHWSPYGLGDMLEKANLYAQLYIRPNE
                     QNLSRSLFLATGDVLPLNEKGERVWPKAQDDASFVLVDASCSAEAVARISPRTATFHK
                     GQLVWGSVAG"
     gene            16869..17159
                     /locus_tag="IRB70_002806"
     CDS             16869..17159
                     /locus_tag="IRB70_002806"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632696.1"
                     /translation="MSVSAEMDIIFEEYALIDVVWITICLRENIISFADFCLLRIANI
                     TLIGARLMGNVAALFHSGSRHVGAGSGGLNIGYIQWTRFAAMTYQASPNTHS"
     gene            17175..18224
                     /gene="yahK"
                     /locus_tag="IRB70_002807"
     CDS             17175..18224
                     /gene="yahK"
                     /locus_tag="IRB70_002807"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase YahK"
                     /protein_id="HBC0632697.1"
                     /translation="MKIRAVGAYSAKQPLEPMDITRREPGPHDVKIEIAYCGVCHSDI
                     HQVRSEWAGTVYPCVPGHEIVGRVVAVGDQVEKHAPGDLVGVGCIVDSCKHCEECEDG
                     LENYCDHMTGTYNSPTPDEPGHTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAG
                     ITTYSPLRHWQAGPGKKVGVVGIGGLGHMGIKLAHAMGAHVVAFTTSESKREAAKALG
                     ADEVVNSRNADEMAAHLKSFDFILNTVAAPHNLDDFTTLLKRDGTMTLVGAPATPHKS
                     PEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEHGIVADIEMIRADQINEAYERMLRG
                     DVKYRFVIDNRTLTD"
     gene            18467..19282
                     /locus_tag="IRB70_002808"
     CDS             18467..19282
                     /locus_tag="IRB70_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632698.1"
                     /translation="MISLKAPHNNLMPYTQQSILNTVKNNQLSEDIKSSLVSCVDIFK
                     VLIKQYYDYPYDCRDDLVDDDKLIHLMAAVRDCEWSDDNALTINVQFNDFPGFYDWMD
                     YPDHPVKFVFRILENQKGTVWVYDQDDAFLDIKANVQAGRFTGLKKLEQFIDSVRTDC
                     KCILLEHHMPLLRLFPKGKECMHVEKWLREMSSIPETDAPIKQALAHGLLLHLKNIYP
                     VFPESLVRLLLSVLDVKTYRDDARLNEWISNRVQELGDRYYPVNKHVKIRYTL"
     gene            19696..19941
                     /locus_tag="IRB70_002809"
     CDS             19696..19941
                     /locus_tag="IRB70_002809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632699.1"
                     /translation="MAVQLFITLLNQIPLLSSLQSETLPLFGYSGRVRAMKKAHTGES
                     GLKWEAKDSSKLIGNKDHALRGLSSPMVGIRQIRLIT"
     gene            complement(19958..20629)
                     /locus_tag="IRB70_002810"
     CDS             complement(19958..20629)
                     /locus_tag="IRB70_002810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysE family transporter"
                     /protein_id="HBC0632700.1"
                     /translation="MMKLLHLFMDEITMDPLHAVYLTIGLFVITFFNPGANLFVVVQT
                     SLASGRRAGVLTGLGVALGDAFYSGLGLFGLATLITQCEEIFSLIRIVGGAYLLWFAW
                     CSMRRQSTPQMSTLQQPINAPWYVFFRRGLITDLSNPQTVLFFISIFSVTLNAETPTW
                     ARLMAWAGIVLASIIWRVFLSQAFSLPAVRRAYGRMQRVASRVIGAIIGVFALRLIYE
                     GVTQR"
     gene            20776..21051
                     /locus_tag="IRB70_002811"
     CDS             20776..21051
                     /locus_tag="IRB70_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBC0632701.1"
                     /translation="MKIISKMLVGALAFAVTNVYAAELMTKAEFEKVESQYEKIGDIS
                     TSNEMSTADAKEDLIKKADEKGADVLVLTSGQTDNKIHGTANIYKKK"
     gene            complement(21152..22738)
                     /gene="prpR"
                     /locus_tag="IRB70_002812"
     CDS             complement(21152..22738)
                     /gene="prpR"
                     /locus_tag="IRB70_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate catabolism operon regulatory protein
                     PrpR"
                     /protein_id="HBC0632702.1"
                     /translation="MAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQL
                     GFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPSGYDVLQALAKAGK
                     LTSSIGVVTYQETIPALVAFQKTFNLRLDQRSYITEEDARGQINELKANGTEAVVGAG
                     LITDLAEEAGMTGIFIYSAATVRQAFSDALDMTRMSLRHNTHDATRNALRTRYVLGDM
                     LGQSPQMEQVRQTILLYARSSAAVLIEGETGTGKELAAQAIHREYFARHDARQGKKSH
                     PFVAVNCGAIAESLLEAELFGYEEGAFTGSRRGGRAGLFEIAHGGTLFLDEIGEMPLP
                     LQTRLLRVLEEKEVTRVGGHQPVPVDVRVISATHCNLEEDMRQGEFRRDLFYRLSILR
                     LQLPPLRERVTDILPLAESFLKVSLAALSAPFSAALRQGLQASETVLVHYDWPGNIRE
                     LRNMMERLALFLSVEPTPDLTPQFLQLLLPELARESAKTPAPRLLTPQQALEKFNGDK
                     TAAANYLGISRTTFWRRLKS"
     gene            22977..23867
                     /gene="prpB"
                     /locus_tag="IRB70_002813"
     CDS             22977..23867
                     /gene="prpB"
                     /locus_tag="IRB70_002813"
                     /EC_number="4.1.3.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylisocitrate lyase"
                     /protein_id="HBC0632703.1"
                     /translation="MSLHSPGKAFRAALSKETPLQIVGTINANHALLAQRAGYQAIYL
                     SGGGVAAGSLGLPDLGISTLDDVLTDIRRITDVCSLPLLVDADIGFGSSAFNVARTVK
                     SMIKAGAAGLHIEDQVGAKRCGHRPNKAIVSKEEMVDRIRAAVDAKTDPDFVIMARTD
                     ALAVEGLDAAIERAQAYVEAGAEMLFPEAITELAMYRQFADAVQVPILANITEFGATP
                     LFTTDELRSAHVAMALYPLSAFRAMNRAAEHVYNILRQEGTQKSVIDTMQTRNELYES
                     INYYQYEEKLDDLFARSQAK"
     gene            23912..25081
                     /gene="prpC"
                     /locus_tag="IRB70_002814"
     CDS             23912..25081
                     /gene="prpC"
                     /locus_tag="IRB70_002814"
                     /EC_number="2.3.3.16"
                     /EC_number="2.3.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate synthase"
                     /protein_id="HBC0632704.1"
                     /translation="MSDTTILQNSTHVIKPKKSVALSGVPAGNTALCTVGKSGNDLHY
                     RGYDILDLAEHCEFEEVAHLLIHGKLPTRDELAAYKTKLKALRGLPANVRTVLEALPA
                     ASHPMDVMRTGVSALGCTLPEKEGHTVSGARDIADKLLASLSSILLYWYHYSHNGERI
                     QPETDDDSIGGHFLHLLHGEKPSQSWEKAMHISLVLYAEHEFNASTFTSRVIAGTGSD
                     MYSAIIGAIGALRGPKHGGANEVSLEIQQRYETPDEAEADIRKRVENKEVVIGFGHPV
                     YTIADPRHQVIKRVAKQLSQEGGSLKMYNIADRLETVMWESKKMFPNLDWFSAVSYNM
                     MGVPTEMFTPLFVIARVTGWAAHIIEQRQDNKIIRPSANYVGPEDRQFVALDKRQ"
     gene            25115..26566
                     /gene="prpD"
                     /locus_tag="IRB70_002815"
     CDS             25115..26566
                     /gene="prpD"
                     /locus_tag="IRB70_002815"
                     /EC_number="4.2.1.79"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-methylcitrate dehydratase"
                     /protein_id="HBC0632705.1"
                     /translation="MSAQINNIRPEFDREIVDIVDYVMNYEISSRVAYDTAHYCLLDT
                     LGCGLEALEYPACKKLLGPIVPGTVVPNGVRVPGTQFQLDPVQAAFNIGAMIRWLDFN
                     DTWLAAEWGHPSDNLGGILATADWLSRNAVASGKAPLTMKQVLTGMIKAHEIQGCIAL
                     ENSFNRVGLDHVLLVKVASTAVVAEMLGLTREEILNAVSLAWVDGQSLRTYRHAPNTG
                     TRKSWAAGDATSRAVRLALMAKTGEMGYPSALTAPVWGFYDVSFKGESFRFQRPYGSY
                     VMENVLFKISFPAEFHSQTAVEAAMTLYEQMQAAGKTAADIEKVTIRTHEACIRIIDK
                     KGPLNNPADRDHCIQYMVAIPLLFGRLTAADYEDNVAQDKRIDTLREKINCFEDPAFT
                     ADYHDPEKRAIANAITLEFTDGTRFEEVVVEYPIGHARRRHDGIPKLVDKFKINLARQ
                     FPTRQQQRILEVSLDRTRLEQMPVNEYLDLYVI"
     gene            26606..28492
                     /gene="prpE"
                     /locus_tag="IRB70_002816"
     CDS             26606..28492
                     /gene="prpE"
                     /locus_tag="IRB70_002816"
                     /EC_number="6.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate--CoA ligase"
                     /protein_id="HBC0632706.1"
                     /translation="MSFSEFYQRSINEPEKFWAEQARRIDWQTPFTQTLDHSNPPFAR
                     WFCEGRTNLCHNAIDRWLEKQPEALALIAVSSETEEERTFTFRQLHDEVNAVASMLRS
                     LGVRRGDRVLVYMPMIAEAHITLLACARIGAIHSVVFGGFASHSVAARIDDAKPVLIV
                     SADAGARGGKIIPYKKLLDDAISQAQHQPRHVLLVDRGLAKMARVSGRDVDFASLRHQ
                     HIGARVPVAWLESNETSCILYTSGTTGKPKGVQRDVGGYAVALATSMDTIFGGKAGGV
                     FFCASDIGWVVGHSYIVYAPLLAGMATIVYEGLPTWPDCGVWWKIVEKYQVSRMFSAP
                     TAIRVLKKFPTAEIRKHDLSSLEVLYLAGEPLDEPTASWVSNTLDVPVIDNYWQTESG
                     WPIMAIARGLDDRPTRLGSPGVPMYGYNVQLLNEVTGEPCGVNEKGMLVVEGPLPPGC
                     IQTIWGDDDRFVKTYWSLFSRPVYATFDWGIRDADGYHFILGRTDDVINVAGHRLGTR
                     EIEESISSHPGVAEVAVVGVKDALKGQVAVAFVIPKESDSLEDREVAHSQEKAIMALV
                     DSQIGNFGRPAHVWFVSQLPKTRSGKMLRRTIQAICEGRDPGDLTTIDDPASLDQIRQ
                     AMEE"
     gene            28729..29988
                     /gene="codB"
                     /locus_tag="IRB70_002817"
     CDS             28729..29988
                     /gene="codB"
                     /locus_tag="IRB70_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBC0632707.1"
                     /translation="MSQDNNFSQGPVPQSARKGVLALTFVMLGLTFFSASMWTGGTLG
                     TGLSYHDFFLAVLIGNLLLGIYTSFLGYIGAKTGLTTHLLARFSFGVKGSWLPSLLLG
                     GTQVGWFGVGVAMFAIPVGKATGLDINLLIAVSGVLMTVTVFFGISALTVLSVIAVPA
                     IACLGGYSVWLAVNGMGGLEALKAVVPAQPLDFNVALALVVGSFISAGTLTADFVRFG
                     RNAKLAVLVAMVAFFLGNSLMFIFGAAGAAALGMADISDVMIAQGLLLPAIVVLGLNI
                     WTTNDNALYASGLGFANITGMSSKTLSVINGIIGTVCALWLYNNFVGWLTFLSAAIPP
                     VGGVIIADYLMNRRRYEHFATTRMMSVNWVAILAVALGIAAGHWLPGIVPVNAVLGGA
                     LSYLILNPILNRKTTAAMTHVEANSVE"
     gene            29978..31261
                     /gene="codA"
                     /locus_tag="IRB70_002818"
     CDS             29978..31261
                     /gene="codA"
                     /locus_tag="IRB70_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine/isoguanine deaminase"
                     /protein_id="HBC0632708.1"
                     /translation="MSNNALQTIINARLPGKEGLWQIHLHDGKISAIDVQSGVMPITE
                     NSLDAEQGLVIPPFVEPHIHLDTTQTAGQPNWNQSGTLFEGIERWAERKALLTHDDVK
                     QRAWQTLKWQIANGIQHVRTHVDVSDATLTALKAMLEVKQEVAPWIDLQIVAFPQEGI
                     LSYPNGEALLEEALRLGADVVGAIPHFEFTREYGVESLHKTFALAQKYDRLIDVHCDE
                     IDDEQSRFVETVAALAHREGMGARVTASHTTAMHSYNGAYTSRLFRLLKMSGINFVAN
                     PLVNIHLQGRFDTYPKRRGITRVKEMLESGINVCFGHDDVFDPWYPLGTANMLQVLHM
                     GLHVCQLMGYGQINDGLNLITHHSARTLNLQDYGIAAGNSANLIILPAENGFDALRRQ
                     VPVRYSVRGGKVIASTQPAQTTVYLEQPEAIDYKR"
     gene            complement(31301..32200)
                     /gene="cynR"
                     /locus_tag="IRB70_002819"
     CDS             complement(31301..32200)
                     /gene="cynR"
                     /locus_tag="IRB70_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CynR"
                     /protein_id="HBC0632709.1"
                     /translation="MLSRHINYFLAVAEHGSFTRAASALHVSQPALSQQIRQLEESLG
                     VPLFDRSGRTIRLTDAGEVWRQYASRALQELGAGKRAIHDVADLTRGLLRIAVTPTFT
                     SYFIGPLMADFYARYPGITLQLQEMSQEKIEDLLCRDELDVGIAFAPVHSPELEAIPL
                     LTESLALVVAQHHPLAACEQVALSRLHDEKLVLLSAEFATREQIDHYCEKAGLHPQVV
                     IEANSISAVLELIRRTSLSTLLPAAIATQHDGLKAISLAPPLLERTAVLLRRKNSWQT
                     AAAKAFLHMALEECADVGGHESR"
     gene            32310..32969
                     /gene="cynT"
                     /locus_tag="IRB70_002820"
     CDS             32310..32969
                     /gene="cynT"
                     /locus_tag="IRB70_002820"
                     /EC_number="4.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase CynT"
                     /protein_id="HBC0632710.1"
                     /translation="MKEIIDGFLKFQREAFPKREALFKQLATQQSPRTLFISCSDSRL
                     VPELVTQREPGDLFVIRNAGNIVPSYGPEPGGVSASVEYAVAALRVSDIVICGHSNCG
                     AMTSIASCQCMDHMPAVSHWLRYADSARVVNEARPHPDLPSKAAAMVRENVIAQLANL
                     QTHPSVRLALEEGRIALHGWVYDIASGSIAAFDGATRQFVPLAANPRVCAIPLRQPTA
                     A"
     gene            33000..33470
                     /gene="cynS"
                     /locus_tag="IRB70_002821"
     CDS             33000..33470
                     /gene="cynS"
                     /locus_tag="IRB70_002821"
                     /EC_number="4.2.1.104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanase"
                     /protein_id="HBC0632711.1"
                     /translation="MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVT
                     AALLGQQALPADAARLVGAKLDLDEDAILLLQMIPLRGCIDDRIPTDPTMYRFYEMLQ
                     VYGTTLKALVHEKFGDGIISAINFKLDVKKVADPEGGERAVITLDGKYLPTKPF"
     gene            33476..34657
                     /gene="cynX"
                     /locus_tag="IRB70_002822"
     CDS             33476..34657
                     /gene="cynX"
                     /locus_tag="IRB70_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308421.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyanate transporter CynX"
                     /protein_id="HBC0632712.1"
                     /translation="MRNHQKTFTMLLVLVLIGLNMRPLLTSVGPLLPQLRQASGMSFS
                     VAALLTALPVVTMGGLALAGSWLHQHVSERRSVAISLLLIAVGALMRELYPQSALLLS
                     SVLLGGVGIGIIQAVMPSVIKRRFQHRTPLVMGLWSAALMGGGGLGAAITPWLVQHSE
                     TWYQTLAWWALPAVVALFAWWWQNAREVASSHKTTTTPVRVVFTPRAWTLGVYFGLIN
                     GGYASLIAWLPAFYIEIGASAQYSGSLLALMTLGQAAGALLMPAMARHQDRRKLLMLA
                     LALQLVGFCGFIWLPLQLPVFWAMVCGLGLGGAFPLCLLLALDHSAQPAIAGKLVAFM
                     QGIGFIIAGLAPWFSGVLRSISGNYLMDWAFHALCVVGLMIITLRFAPARFPQLWVKE
                     A"
BASE COUNT         8165 a         8904 c         9389 g         8299 t
ORIGIN      
        1 atctgccgca gataaatgaa ttaatagtct gtatcaggaa tgttcgggtt aaatatcagc
       61 aaaaagccag catcatgaat actggatatg aagcatgaga gttacctcag tgttttatat
      121 aaggattcgg tcctcatagt agaacggtaa ctctcaatct gataggttcc tgagtcagtt
      181 cacatcacga ctcatttttt tcgctctcac cggcatccca tttgccacat aatatcccgc
      241 cgtgctcctc ggcaacgcat ccttcccgcg aatcatatcc gctattttct cgccaatcat
      301 aatggtcgtg gcgttcaaat tgccggtgat aatttgcggc ataattgacg catccaccac
      361 gcgcaggcct tccagcccgt gtacgcggcc ttcgccgtca accactgcca tctcgtcata
      421 acccattttg caggtaccgc acgggtggaa ggcggtttcg gcgtggttac gcacgaactc
      481 atcgagctgc tcatccgtct ggcattcgac accggggctg atttcgcggc cacgatactg
      541 atccagcgcc ggttgatgca tgatctcccg ggtgatgcga attgcgtcgc ggaactcctg
      601 ccagtcctgc tcgtgcgaca tgtagttaaa cagaatcgct ggatgctggt gcggggcgcg
      661 ggatttaatc cgcacatgcc cacggcttgg cgagcgcatc gatccgacgt ggcactggaa
      721 gccgtgctct ttcactgcgt tcgagccgtt atagttaatc gctactggca ggaaatggta
      781 ctgaatattc ggccacgcaa attcctcacg gctgcgaata aatccgcctg cttcaaagtg
      841 gttgctggca ccaatgccgg tgccgccaaa cagccactcc gcaccgattt tcggctgatt
      901 ccaccactgc agggcagggt agagggaaac cggttctttg cactcatatt gcagatacat
      961 ctccaggtga tcctgaagat tttcgccgac gccaggtaat tcatgcacca gcggaatatc
     1021 aaactccgcc agcagttcag cgttgccgac gccggagcgt tgcaggatct gcggtgaagc
     1081 aatcgcgcct gcacataaca gcacttcttt attcgccgcc gcgcgggtcg gaatggtgct
     1141 gtcgccttcc agccactcga cgcccaccgc gcgtttgccg tcaaaaatga tgtgatcggt
     1201 catggcgtga gtacgaatag tcaggttagg gcgcgatttg gcctgatcga gatagccacg
     1261 cgcggtgctg gcgcgacggc catgcggcgt gacggtgcga tccatcgggc caaaaccttc
     1321 ttgctgatag ccgttgagat cgtccgtgcg cgggtagccc gcctgcacgc ccgcttcaat
     1381 catcgcttca aacagcggat tgacgccggg tttggaggtg gtgacgctca ccgggccatc
     1441 accgccgtgg tagtcgttct cgcccacatc gcgagtctcg gccttgcggt agtagggcag
     1501 gcagtcgaga taactccagt tctccagacc aggttcttgt gcccagttat cgagatccag
     1561 cgcattgcca cggatgtagc acataccatt gatcagcgat gaaccgccca gacctttgcc
     1621 gcgtccgcac tccatgcggc ggttgttcat aaacggttcg ggttccgtct cataggccca
     1681 gttgtagcgt ttgccctgta acgggaacgc cagcgcggcg ggcatctggg tgcggaagtc
     1741 aaagcgatag tccgggccgc ctgcttcaag cagcagcacg gttatgttcg gatcttcagt
     1801 cagacgggta gcgaggacgt tgccggctga gccggcacca ataatgatgt agtcaaattg
     1861 caaataaacc tcctggttag aatatggact ggaatttagc catctcaacc tggatggact
     1921 tcacctgggt gtaactctgg agcgtcatca cgccgttctc gcgaccaatg ccggagtgtt
     1981 tgtagccgcc aacgggcatc tctgccgggg attcgcccca ggtgttgatc cagcaaatac
     2041 ccgcttccag ctgatgaatg acgcgatgcg cgcggttcag gtccgccgtc acgatacccg
     2101 ccgccagacc gtagtcggta tcgttagcgc ggcgaatgac ttcgtcttcc gactcgtagg
     2161 tcagaatgga catcaccggc ccgaaaatct cttcgcgcac gatggtcatt tcgtcgcggc
     2221 aatcggtgaa cacggtcggt gcaacccatg cgccgttatc gaagccatcg cctttcagta
     2281 catcgccgcc gcacagtacg cgcgcgcctt cctctttgcc tttggcgata tagcgcagca
     2341 cgttatcgcg atgcgggaag ctgaccagcg ggccgaagtt agtttgcgga tcgaaaacgt
     2401 cgcccgcgcg aatgcgctca acgcgcgcca gaatcttttg ttcaaatgcg gctttgcatt
     2461 tcgtcggaac gaagacgcga gtgccgttgg tacacacctg accggagctg aagaaattcg
     2521 ccatcatggc gatatcggcg gcgagatcga gatccgcatc gtcaaaaacg atcagcggtg
     2581 atttaccgcc cagctccatg gtcacttctt tcagggaaga ggccgccgag ttagccatca
     2641 cttttttgcc gctggcgaca ccgccggtaa atgacacttt ggcaatgccc ggatgctcgg
     2701 tcagatactg cccggtttcc gcacctacgc ccggcagcac gttaaatacg ccgtccggca
     2761 ggcccgcttc gctgtaaatg tcggccagct ttaacgcggt aagcggggtg acttcgctcg
     2821 gtttgaaaat catcgcgttg cctgccgcca gcgccggtgc ggatttccac aaggcaatct
     2881 ggatcgggta gttccatgcg ccaatccctg ccactacgcc cagcggttcg cggcgggtat
     2941 aaacaaatga cgtctcacgc aatgggatct ggctgccttc cagcgccggg atcagcccgg
     3001 cgtagtactc cagcacgtcc gcaccggtaa cgatatcgac ggttgatgtt tccgaatacg
     3061 cttttccggt gtcgagggtt tccagttttg cgagttcgtc attgcgttca cgcagaatat
     3121 caacggcccg acgcagaata cgcgagcgtt ccatagcggt catcgccgcc cagatttttt
     3181 gcccctgttg ggcactcttc acggcgcgat cgacatcctc acgcccggcg gcctgcacgg
     3241 tcgccagcac gttaccgttg gccgggttaa tggtctcgaa ggtgcgaccg ctggtggcgg
     3301 aggtataacc accatgtata taaagctgct gttctgccat tcgggacatc acgtctcctc
     3361 ggttaatcgg tgggtaaatg ctgagtaata aagtgacggg tcagcgagtg tgcgagaggt
     3421 ttatccagcg gtttgccgct cagtgccgcg cgcagccata atccgtcaat cagcgcggca
     3481 aggccgtagc ccgcttcctg tgcctggtgg cgcggtaact cgcggtgaaa ttcgctcacc
     3541 agattcgaca acaagcggcg gctgctcacc tgctgcaaac ggtaaagcat cggctgatgc
     3601 atactgctgg cccaaaacgc caaccaggct ttcatcgcag cattactgac ctgcgtttca
     3661 tcgaaattcc cgtcaacaat cgcctgtaat cgctgctctg ggctaccatc cgttagcgcg
     3721 tgtaatcgat tcaaaaccgc gtcacgcagc tgactggtga tatcgcgcat ggttgcttcc
     3781 agcagaccat ttttgtccct gaaatagtgg ctgatgatcc ccgtagaaac gcctgcacgg
     3841 cgggcgatct gcgcgatcgt tgcatcgtgc atgcccactt catttattgc ttccagcgtg
     3901 gcgtcgatca gttgtctgcg ccggatcgac tgcatcccca atttgggcat tttcgccact
     3961 ccattcatca gcgttgttta tctattaaag cggttattga ttggacgttc aatataaaat
     4021 gtgtcttaat tgttacgagt ttgattttaa atggtaacaa taacagtggg gatactggat
     4081 gacagacctt tcacacagca gggaaaagga caaaatcaat ccggtggtgt tttacacttc
     4141 cgccggactg attttgttgt tttccctgac aacgatcctg tttcgcgact tctcggccct
     4201 gtggattggc cgcacgctgg actgggtctc taaaaccttc ggttggtact atctgctggc
     4261 ggcaacgctc tatattgtct ttgtggtctg tatcgcttgt tcgcgttttg gttcggtgaa
     4321 gctcgggcca gaacaatcaa aaccggaatt cagtctgctg agttgggcgg cgatgctgtt
     4381 tgctgccggg atcggtatcg acctgatgtt cttctccgta gccgaaccgg tcacgcagta
     4441 tatgcagccg ccggaaggcg cgggtcagac gattgaggcc gcgcgtcagg cgatggtctg
     4501 gacgctgttt cactacggct taaccggctg gtcgatgtat gcgctgatgg gcatggcgct
     4561 cggatacttt agctatcgtt ataatttgcc gctcaccatc cgctcagcgc tgtacccgat
     4621 cttcggtaaa cggattaacg ggccgatagg tcactcagtg gatattgcag cggtgatcgg
     4681 caccatcttc ggtattgcca ctacgctcgg tattggtgtg gtgcagctta actatggctt
     4741 gagcgtactg tttgatattc ccgattcaat ggcggcgaaa gcggcactga tcgccttgtc
     4801 ggtgatcatc gcaacgatct ctgtcacctc cggtgtcgat aagggcattc gcgtgttatc
     4861 ggaacttaac gttgcgctgg cgctggggtt gatcctgttt gtgctgttta tgggcgacac
     4921 ctcgttcctg cttaatgcgc tggtgctgaa cgttggcgac tatgtgaatc gctttatggg
     4981 catgacgctc aacagttttg ccttcgaccg tccggttgag tggatgaata actggacgct
     5041 cttcttctgg gcatggtggg tggcatggtc gccgtttgtc ggcttgttcc tggcgcgtat
     5101 ctcgcgtggg cgtaccattc gccagttcgt gctgggcacg ttgattattc cgtttacctt
     5161 cacgctgtta tggctctcgg tattcggcaa tagcgcgctg tatgaaatca tccacggcgg
     5221 cgcggcattt gccgaggaag cgatggtcca tccggagcgc ggcttctaca gcctgctggc
     5281 gcagtatccg gcgtttacct ttagcgcctc cgtcgccacc attactggcc tgctgtttta
     5341 tgtgacctcg gcggactccg gggcgctggt gctggggaat ttcacctcgc agcttaaaga
     5401 tatcaacagc gacgcccccg gctggctgcg cgtcttctgg tcggtggcga ttggcctgct
     5461 gacgctaggc atgctgatga ccaacgggat atccgcgctg caaaacacca cggtgattat
     5521 gggcctgccg ttcagctttg tgatcttctt cgtgatggcg gggttgtata aatctctgaa
     5581 ggtagaagat taccgccgtg aaagtgccaa ccgcgatacc gcgccgcgac cgctggggct
     5641 tcaggatcgc ctgagctgga aaaaacgtct ctcgcgcctg atgaattatc cgggcacgcg
     5701 ttacactaaa cagatgatgg agacggtctg ttatccggca atggaagaag tggcgcagga
     5761 actgcggttg cgcggcgcgt acgtggagct aaaaaacctg ccgccggaag agggacaaca
     5821 gttggggcat ctggatttgt tggtgcatat gggcgaagag caaaactttg tctatcagat
     5881 ttggccgcag caatattcgg tgccgggctt tacctaccgc gcacgtagcg ggaaatcgac
     5941 ctactaccgg ctggaaacct tcctgttaga aggcagccag ggcaacgacc tgatggacta
     6001 cagcaaagag caggtgatca ccgatattct tgaccagtac gagcggcatc ttaactttat
     6061 ccatctccat cgtgaagcgc cgggccatag cgtgatgttc ccggacgcgt gattgttttt
     6121 gcataaaacc gcgccatgtc tgcatatggc gcggtttctc ttacctcttg atacgttata
     6181 tctgtacagt taagccctta gtatcgattg atgattgcca ggcaacagat aataaaaaag
     6241 aaaagaacta ttgaagccca aaacctacgt ttggactgtt gtgaatgttc aataagctta
     6301 gtcttattta atgtaaatat tggtgctaat ttgaaatgac gctttattca tggggaacgc
     6361 gtagcgcaaa tcaactaaaa tcaatgtaac cgtttgttgt ttaaggttta attgtctgtg
     6421 tctgatattt tattgattgt tttaaatatt gtttttattg tcattgttat aatgttggct
     6481 atctattgct gaatggattc agtcttaaaa agcaggttgt taagagatag gcatagagta
     6541 atgacgtgta tgcataacca acatctttac tcattatgtc attgaatgtt gacgctatgt
     6601 gtttatgagg ttgaggtatt ttcagttgat ctggattgtt aaattcatat aatgcgcctt
     6661 tactcatgaa tgggcgtcaa tacgtagtgg gaaattataa atatcgaaat agtccaacta
     6721 cttctttatt accaaaaatg agtatctgaa ttttaatatt gcattcttgc gtgattatct
     6781 cctgagtttg acttgtgatt acctttttaa ggtatttagc gtaactgttt ttgagcgagc
     6841 atcagaggta aagataatct tcttgatagt gatgtgggat gttatacgta tggcatcgct
     6901 aatgtttatg gttacccctt atgtgtgctc aggaatccac aggtaatcac tcatactgaa
     6961 cagcgataaa agataaaagg tgtgttcatg aattcatgtg attttcgtgt ttttctgcaa
     7021 gagttcggta caacggttca tttgtcattg cctggtagcg tatccgagaa agaacgactg
     7081 ctactcaagc tgctgatgca gggaatgtct gtaacagaaa tatcacagta cagaaatcgc
     7141 agtgcaaaga ccatttcaca tcaaaagaaa cagctctttg agaaactggg gattcagagc
     7201 gatattactt tctggcggga tattttcttt cagtacaatc cggagatcat atccgccacg
     7261 ggtaataata gtcacaaata tattaatgat aatcactatc accatatcgt cacgcctgaa
     7321 gccatcagtc tggcgttgga aaaccatgaa tttaaaccgt ggatccaacc ggttttctgc
     7381 gcgcagactg gggtactgac gggctgtgag gtgcttgttc gctgggaaca tccgcaaacg
     7441 ggaattatcc caccggatca gtttattcct ctggcggagt catctggtct tatcgtcata
     7501 atgactcgcc agctgatgaa acagactgcg gatattctga tgccagtaaa acatttgctg
     7561 ccggataatt tccatattgg tatcaacgtc tcggcgggct gttttttggc tgcgggattt
     7621 gaaaaagagt gtctgaacct ggttaagaaa ttaggtaacg ataaaatcaa actggttctc
     7681 gagttaacgg aacgtaaccc tattccggta acgccagaag ccagagcgat atttgacagc
     7741 cttcatcagc acaacattac ctttgcgctg gatgactttg gtacgggtta tgcaacctat
     7801 cgttacttgc aggcgttccc ggtcgatttt attaagatcg ataagtcatt tgtgcaaatg
     7861 gcgagcgtgg acgaaatatc cggtcatatt gtggacaata ttgtcgaact ggcgcgtaag
     7921 cctggtctga gtatcgtggc ggaaggggta gaaacccagg agcaggcgga tttaatgatc
     7981 ggcaaaggcg ttcacttttt gcagggctat ttgtactctc cgccagtacc gggtaataaa
     8041 tttatctctg aatgggtaat gaaagccggt ggttgatgta aaccgctatt cacagcgcat
     8101 cgggaggttg gcagcgatta attctcccga tgcagtaaat cctgatagat ccccgttaat
     8161 atgccatttg gcgcaaattg ttttttaatc cactgcgtca cctgaccggt ggcagagtgc
     8221 tgggtcgcca gtaacatgcg tgaatcctgg cgcggattat ggatttgtcg ggtaaccagc
     8281 agggattgcg ccatcgcctc acggaccatg taatccggca aaaaaccaat tccttcgcct
     8341 aaaatctggc actgacattt ggtgttgaaa tctggcacca gaatcgactc ctgcccatgc
     8401 agcaaccagc ccactttttt attaatcgta tgcgcggtgt cttccaccat gatattaggg
     8461 tagagacgca gctggctttc ggcgatgggt tccggcacaa aggctaacgg gtgatccggg
     8521 gcgatagcaa aagcccagcg aatcgcgcca atctccgtgt aatcaatgcc gccgccgtcc
     8581 agcagtgtgt cgggcgcgcc gatagcaata ttcgcctgat tattaataat cgcatcccag
     8641 acgccgttat acacttcggt ggtgacggta atctggcagg taggaaactg ctttttcagc
     8701 acctgtaata agcgtgcggt gtgtttgggc gtataaagca gctgattaat acaaatgcgc
     8761 acacgcgctt ctatgccctg cgaaatagta tcgatactgc gtttaatggc atgaaaatca
     8821 ttcagcaggt cggtagcttt gcggaaaaaa taacgcccgg actccgttaa ctcaatgctg
     8881 cgggtactgc gagtgaacag caccacatcc agccccgtct ccatacgttt aatggtgtag
     8941 ctaatggcgg aagtggttaa acccaactct tctgcggctt tactgaagct gccaaaacgc
     9001 gcagcggtag taaatgccaa cagattctct tcggtaaaaa ttgagttcat tgacccgctc
     9061 ccgccatttt cgattctgaa tttctccagc catgactgta gaggtatcca ttaaagatgg
     9121 ataatcattt ttgaataact tttaataccc gtcgcttttg gtcgtcgctt cgcttaattt
     9181 ttgtccgccg tattctgaaa ttatccccac gcagttaccc gccagaaaac ccagtaatgt
     9241 caccgtccag ttcatcccgc tggcaaaaaa tagcgtcatg ccgagaaagc ccccgggaat
     9301 aaaagacagt aaccagaaac gtccttgcca gaccaccacc gccgagaagg gtacagtcat
     9361 aatcacgctc gcccagaacg tggacaatcc actcaccgag gccagccaac cggcagccag
     9421 cgcggcgaaa aacgcccaca ccatcccgga ataattaacc gccaggcttc tgataaaccc
     9481 cgatttaccg ccgcctgcgg cataaaaact gcaaaaggcg acgaagccaa tggttcctaa
     9541 taattcccat ccctgagaga gcccgacatg tgaagacact aactgccaaa gccctgcaca
     9601 aataccgacg gtgacacccg ttgccgtgag tccgttcatc ttgttcccct ctggttagac
     9661 atggacgaaa gctactctta catgtgcaga ctatagagaa ataaaacctg attgagtgaa
     9721 agggtatcgg gtcaaagaaa caaatattgc actaccgcac actgcgaaaa gattgttgaa
     9781 catcattcaa caaaaaggcg aaatacggcg aattaaattt aagcgggttc ttttatcaga
     9841 ttatcgttgc tattctcaat tcatcgaaaa cagccacaaa aaccagggga atgtgaatga
     9901 ctataaaaaa tctacctgcc gactatttat tggctgcgca acagggtgat atcgataaag
     9961 taaaaacctg ccttgcgctg ggtgtcgata ttaatacctg cgatcgtcag gggaaaacgg
    10021 caattacgct ggcaagttta tatcagcaat atgcttgcgt tcaggcatta attgacgccg
    10081 gagcggatat taataagcaa gatcatacct gtttaaatcc ttttttaatt agctgcctga
    10141 ccggcgattt aaccctgtta cggattattt taccggctaa acccgatctt aattgcgtaa
    10201 cccgttttgg cggtgtcggc ctgacgcctg cctgtgaaaa aggccattta agtattgtaa
    10261 aagagctttt ggcgcatacg gagattaacg ttaaccagac caaccatgta ggctggacgc
    10321 cgctactgga agcgattgtg cttaatgatg gcgggattaa acagcaggcg attgtccagt
    10381 tattgctgga acacggtgcc agtccgcatc tgacggataa atatggcaaa acgccgctgg
    10441 aactggcgcg ggaacgaggc tttgaagaga ttgcgcagtt actgattgcc gcaggtgcat
    10501 aaaccgggag gcttgctatc aacacaccag aaagacggtg tgtgtggtcg ctaactgcgg
    10561 atgctgattt tctggcgcag cgggggcaag gacaggttga acaggtcttt gccagagcgg
    10621 taaatatcgc acttccggcc cgccagcagt tgctgacgct gctttgtgaa gagtacgaca
    10681 atgcgccaaa cagttgtcgg ttggcactca ctcactttaa tggtctgttc cggcatggtg
    10741 ataaggttca gtttgacgat caaggcatta cggttggtca acatcttcat atagagatga
    10801 gtcattgcca gcgttggctg tccccaacct tgcaaatgac cgctgtgaat tttcacctta
    10861 tcgtctggca acagtggcat gacataattc atcagcacct gggggaaaat gaaaccctgt
    10921 ttaattattg cggcgataat ccgttttatc aggcgttaaa taaagaatta catattaaac
    10981 gacgggcagt tattcaggcc gtaaacgata aacaaaatat cgcctcagca gtcgccagta
    11041 tgatgggctt agggattggc cttacgccat cagccgacga ttatttaaca ggtctggcgc
    11101 ttattttatt tatttccgga catccggcgg aaaaatacaa agaggaattt tatctcggtc
    11161 tgcaacgcgg cagaaataat accacgttat taagtgccat aacgctggaa gccgcattac
    11221 aacaacgctg ccgggaaaat attcatcgtt ttattcataa cattatttat gacatccctg
    11281 ggaacgcaac tcaggcaata gaaaaaatta aacatattgg ctccagttcc ggctgcgaca
    11341 tgctgtatgg catggccgat ggttgtgcgc tgagccaaac ctacggaggg aattatgtca
    11401 gttaaaatag tcattaaacc gaatacctat tttgattctg tctcgctgat gtctatctct
    11461 acgcgtgcaa ataaactcga cggcgtcgag caggcatttg tggcgatggc gaccgaaatg
    11521 aacaaaggcg tactgaagaa tttagggctg ctgacgccgg agctggagca ggcgaaaaac
    11581 ggcgacctga tgattgtcat caacggcaaa gcgggcgcag acaacgagca gttgctggtg
    11641 gagattgaag aactgttcaa caccaaagcg caaagcggct cgcacgaggc gcgttacgcc
    11701 actattgcca gcgccaaaaa gcatatcccg gaaagtaacc tggcagtgat ttcggtcaac
    11761 ggtctgtttg ccgctcgcga agcgcgtcag gcgctgcaaa atgatcttaa cgtgatgctg
    11821 ttttccgata acgtctcggt tgaagatgaa ctggcgctca aacagttggc ccatgaaaaa
    11881 gggctgctgc tgatggggcc agactgcggc acggcgatta tcaacggcgc ggcgctctgc
    11941 tttggtaacg ccgtgcgtcg cggcaacatc ggtattgttg gcgcatccgg caccggtagc
    12001 caggaactga gcgtccgtat ccatgaattt ggcggcggcg tttcgcaact gatcggcacc
    12061 ggcgggcgcg acctgagcga gaaaatcggc ggtctgatga tgctcgacgc catcgggatg
    12121 ctggaaaacg atccgcaaac tgaaattatt gtgcttatct ccaaaccgcc tgcgcctgcg
    12181 gtggcccgca aagtgctgga acgcgcacgc gcctgccgca agccggtggt ggtctgcttc
    12241 cttggtcgtg gcgaaacgcc agtggatgag caggggctac agtttgctcg cggcagcaaa
    12301 gaagcggcgc tgaaagcggt aatgctttcc ggcgtgaaac aggaacatct cgatctgcat
    12361 accctgaacc agccattgat tgctgacgtg cgcgctcgcc tgaagccgca acagaaatac
    12421 attcgtggcc tgttctgcgg cggtacgctg tgtgacgaaa ccatgttcgc ggtgatggaa
    12481 aaacacggcg atgtctacag caacatccag cccgatcctg aattccgcct gaaagatatc
    12541 aaccgcagcg tcaaacatac cttcctcgac tttggcgatg acgattttac caacggcaag
    12601 ccgcatccaa tgattgaccc gaccaaccgc atcagccggt tgatcgaaga agcgcgcgat
    12661 ccagaagtgg cggtgatcgt gatggatttt gtgctcgggt ttggatcgca tgaagatccg
    12721 gtcggttcca ccatcgaggc gatcaaagag gcgaaagcga tcgccgctgc cgaaggacgt
    12781 gagttgatca ttctcgccta tgtgctgggt accgatcttg atacgccatc attagaacaa
    12841 caaagccaga tgttgcttga tgccggagtg attctggcga gcagcagcac caataccgga
    12901 ttgctggcgc gtgaatttat ctgcaaaggg gaggaagcct gatgagccag tcactgttta
    12961 gccaaccatt gaacgttatt aacgtcggca tcgccatgtt tagcgatgac ctgaaaaagc
    13021 agcatgtaga agtgactcaa ctcgactgga cgcccccggg gcagggcaat atgcaggtgg
    13081 tgcaggcgct ggataacatt gctgattcgc cgctggcaga caaaatcgcc gccgcgaatc
    13141 agcaggcgct ggagcgcatt attcagtcac atccggtgct gattggtttt gatcaggcga
    13201 ttaacgtggt gccgggcatg acgccgaaaa ccattcttca cgccgggccg ccggtcacct
    13261 gggaaaaaat gtgcggcgcg atgaaaggcg cggtcaccgg ggcgctggtg ttcgaagggc
    13321 tggcgaaaga tctcgacgag gcggctgaac tggcggcttc cggtgagatc actttctcgc
    13381 cgtgccacga gcacgactgt gtgggatcga tggcgggcgt cacctcggcc tcgatgttta
    13441 tgcacatcgt gaaaaacaaa acctacggca acatcgctta caccaacatg agcgagcaga
    13501 tggcgaagat tttgcgtatg ggtgccaacg atcagagcgt gattgaccgc ctcaactgga
    13561 tgcgtgatgt gcaggggcca atgctgcgcg acgcgatgaa aattatcggc gaaatcgatc
    13621 tgcgcttaat gttggcgcag gcgctgcaca tgggcgatga atgccataac cgcaataacg
    13681 ccgggacgac gctgctgatt caggcgctga caccggggat tattcaggca ggttattccg
    13741 tcgaacaaca gcgcgaagtg tttgagtttg tcgccagcag cgactacttc tccggcccga
    13801 cgtggatggc gatgtgtaaa gcggcgatgg atgcggcgca cggcatcgaa tacagcaccg
    13861 tggtgaccac gatggcgcgt aacggcgtcg agttcggtct gcgggtcagc ggattaccgg
    13921 ggcaatggtt taccggtccg gcgcagcagg tgatcggccc gatgtttgcc ggttataagc
    13981 cggaagattc ggggctggat atcggcgaca gcgccatcac cgaaacctac ggcattggcg
    14041 gatttgctat ggcgaccgcg cctgcaatcg tcgcgctggt gggcggtacg gtggaagagg
    14101 ctatcgattt ctcccgtcag atgcgcgaaa tcactctcgg cgaaaacccc aacgtcacca
    14161 ttccgctgct cggttttatg ggcgtgccgt cggcaatcga catcacccgc gtgggtagca
    14221 gcggcattct gccggtgatc aacaccgcca ttgcccataa agatgcgggc gtcggcatga
    14281 ttggcgcggg cattgtgcat ccccccttcg cctgcttcga gaaagccatt cttggctggt
    14341 gcgaacgtta cggcgtctga ccctccaacc gcaccttacg ataccttctc ccttttgggg
    14401 agaagggcaa cctcactctc ataaccccat caccctctgt agcggacata acaacatgaa
    14461 agaacttgtg gtcgttgcca ttggtggcaa cagcattatc aaagataacg ccagccagtc
    14521 gattgagcat caggcggagg cggtgaaggc cgtcgccgat acggtgctgg aaatgctggc
    14581 ttccgattac gacattgtgc tgacccacgg caacggaccg caggtcggtt tggatttacg
    14641 ccgcgcggag attgcccacg agcgcgaagg gctgccctta acgccgctgg cgaactgtgt
    14701 ggcggatacg caaggcggca ttggctatct gatccagcag gcgctgaata accggctggc
    14761 gcgtcacggc gagaaaaaag ccgtcaccgt ggtgactcag gtggaagtgg ataaaaacga
    14821 tccggggttt gcccatccca ccaagcccat cggcgcattc tttagtgaaa gccagcgtga
    14881 cgaactacaa aaggcaaacc ctgactggcg ttttgttgaa gatgccggac ggggctatcg
    14941 ccgcgtggtc gcctcgccgg aaccgaaacg tattgtcgaa gcacctgcca ttaaggcgct
    15001 gatccaacaa ggttttgtgg tgattggcgc gggcggcggt ggaattccgg tagtgcgtac
    15061 tgaagcgggg gattaccaaa gcgtggacgc ggttatcgac aaagatctct ctaccgcgct
    15121 attggcccgt gaaattcacg ccgacattct ggtgatcacc actggcgtcg aaaaagtgtg
    15181 tattcacttt ggcaaaccgc agcagcaggt gctggatcgg gtggatattg ccaccatgac
    15241 ccgctatatg caggaagggc atttcccacc cggcagcatg ttgccaaaaa tcatcgccag
    15301 cctgacgttc ctggagcagg gcggtaaaga agtgattatc accacgccgg aatgcctgcc
    15361 tgcggcgctg cgtggtgaaa cgggcaccca tattattaaa acgtaaggac gtaagatgaa
    15421 agaaaacaat agccgccgtg agtttctgag ccagagcggt aagatggtca ccgccgccgc
    15481 gctgtttggt acctctgtgc cgctcgccca tgcggcagtc tctggcacaa cccactgcga
    15541 ggcaaataac accatgaaaa tcactgaccc gcactactat ctcgacaacg tgctgctgga
    15601 aaccggtttt gactacgaaa acggtgtggc ggtgcagacc cgcacggcgc accagaccgt
    15661 agagattcag aacggcaaaa ttgttgccct gcgcgagaac aagcagcatc cggaggccac
    15721 gctgccgcac tatgacgcag gcggtaagtt gatgctgccc accacccgcg acatgcatat
    15781 tcatctcgac aaaactttct acggcgggcc gtggcgctcg ctcaatcgcc cggcaggcac
    15841 caccatccag gacatgatta agcttgagca gaaaatgctg ccggaactgc aaccgtacac
    15901 gcaggaacgg gcagaaaaac tgatcgattt attgcagtcg aaaggcacca ccattgcccg
    15961 cagccattgc aatatcgaac cggtttccgg cctgaaaaat ctgcaaaatt tgcaggcggt
    16021 gctggcgcga cgtcaggcgg gcttcgagtg tgaaattgtc gccttcccgc agcacggttt
    16081 gctgctgtcg aaatcggaac ccttaatgcg tgaagcaatg caggcgggtg cgcattacgt
    16141 cggcgggctg gacccgacca gtgtcgatgg cgcgatggaa aaatccctcg acaccatgtt
    16201 ccagattgcg ctggactacg acaaaggcgt cgatattcac ctgcacgaaa ccactccggc
    16261 aggcgtggca gccatcaatt atatggttga aacggtggag aaaacgccgc aactgaaggg
    16321 caagctgacc atcagccacg cctttgcgct ggcaacgctc aatgagcaac aggtagatga
    16381 actggcgcac cggatggcgg cgcagcaaat ttctatcgcc tcgacggtgc cgattggcac
    16441 gttgcatatg ccgctcaaac aactgcacga caaaggcgta aaagtgatga ccggcaccga
    16501 cagcgttatc gaccactggt cgccttacgg cctgggcgac atgctggaaa aagccaatct
    16561 gtacgcgcag ctctatattc gtcctaacga acagaacctc tcccgctcgc tgtttttagc
    16621 cactggcgat gtattgccgc tcaacgaaaa aggcgagcgc gtgtggccca aagcgcagga
    16681 tgacgccagc tttgtgctgg tggacgcctc ctgttccgcc gaggcggtgg cgcgtatttc
    16741 gccgagaacc gcaacgttcc ataaagggca actggtgtgg gggagtgtgg caggttgata
    16801 cgaacttgat atatctgcaa cggtgaacag taagagattt aagccccagg gagtggggcg
    16861 gcctgagtat gagtgtgtcg gcagaaatgg acattatctt tgaagaatat gcccttattg
    16921 acgttgtgtg gataactatt tgtctacgtg aaaatatcat cagttttgcc gatttttgtc
    16981 ttttacggat agcaaatatc acacttatag gcgctcgcct tatggggaac gttgctgctc
    17041 tgtttcattc aggctcgcgg catgttgggg ctggatcggg tggtttaaat attggctata
    17101 ttcaatggac gcgttttgcc gcgatgacat atcaggcatc gccaaataca catagctaat
    17161 caggagtaaa cacaatgaag atcagagctg ttggtgcata ttccgctaaa caaccgctgg
    17221 aaccgatgga tattacccgg cgtgaaccgg gaccgcatga tgtcaaaatt gaaatcgctt
    17281 actgtggcgt ctgccattcc gatatccacc aggtccgttc cgagtgggcg gggacggttt
    17341 acccctgcgt gccgggtcat gaaattgtgg ggcgtgtggt agccgttggt gatcaggtag
    17401 aaaaacatgc gccgggcgat ctggtcggtg tcggctgtat tgtcgacagt tgtaaacatt
    17461 gtgaagagtg tgaagacggg ctggaaaact actgtgatca catgaccggc acctataact
    17521 cgccgacgcc ggacgaaccg ggccatactc tgggcggcta ctcacaacag atcgtcgttc
    17581 atgagcgata tgttttgcgt attcgtcacc cgcaagagca gctggcggcg gtggctcctt
    17641 tgttgtgtgc agggatcacc acgtattcgc cgctacgtca ctggcaggcc gggccgggta
    17701 aaaaagtggg cgtggttggc atcggcggtc tgggacatat ggggattaag ctggcccacg
    17761 cgatgggggc gcatgtggtg gcatttacca cttctgagtc aaaacgcgaa gcggcaaaag
    17821 ccctgggggc cgatgaagtt gttaactcac gcaatgccga tgagatggcg gctcatctga
    17881 agagtttcga tttcattttg aatacagtag ctgcgccaca taatctcgac gattttacca
    17941 ccttgctgaa gcgcgatggc accatgacgc tggttggtgc gcctgcgaca ccgcataaat
    18001 cgccggaagt tttcaacctg atcatgaaac gccgcgcgat agccggctct atgattggcg
    18061 gcattccaga aactcaggag atgctcgatt tttgcgccga acatggcatc gtggctgata
    18121 tagagatgat tcgggccgat caaattaatg aagcctatga gcgaatgctg cgaggtgatg
    18181 tgaaatatcg ttttgttatc gataatcgca cactaacaga ctgaaacaat taataaatac
    18241 cctgtggttt aacatattaa cttcgctctc cacttaactt tttagttaag gagagcgaaa
    18301 taatatcaaa gtagcagtaa aacctataac gtaaattcaa attgttaaat taactccctc
    18361 cagtacacaa tacttcacac gttagttatg agcgatttct gatagtgcct ggtttaatca
    18421 gggctttatt atctgcgacg tttattttta tttaagagag atcgcgatga tatcattaaa
    18481 agctccgcac aataatttga tgccatatac gcaacaaagc atacttaata ctgttaaaaa
    18541 caatcagtta tcagaggata tcaaaagctc cctggtctcc tgtgtcgata tattcaaggt
    18601 tttgattaaa caatattatg attatcctta tgattgtcgt gatgatttag tcgatgacga
    18661 caaactcatt catctcatgg ctgccgtacg agactgtgag tggtcagacg ataacgcact
    18721 caccataaat gtgcagttta atgatttccc tgggttttat gactggatgg attaccctga
    18781 tcacccggtt aagtttgttt ttcgcatact tgaaaatcaa aaagggacag tttgggtata
    18841 tgaccaggat gatgcgtttc ttgatattaa agcaaatgtg caggctggac gctttaccgg
    18901 gcttaagaaa ttagagcagt ttatcgattc agtgcgaaca gattgcaaat gtattcttct
    18961 tgaacaccat atgcctttgc tgagactttt ccctaaaggg aaagagtgta tgcatgtgga
    19021 aaaatggctt cgcgaaatgt cgtctatccc ggagaccgac gcgcccatta agcaggcgct
    19081 tgcgcatgga ttattattac acttaaaaaa tatctaccct gtttttcctg aatcactggt
    19141 gaggttattg ctctctgttc tggacgtaaa aacatacaga gatgatgcgc gattaaatga
    19201 atggatatct aatagagtgc aggaattagg tgacagatat tatcctgtaa ataagcacgt
    19261 taaaatccgc tacactcttt agttcagaaa gggttccacc tgcgagttgt tattccacca
    19321 gagagtgaat cgcaaagcag gtgatcattt catctgtata tccgtatgcc aaatggcatt
    19381 ccaccgcctt tttcgccgat attttgttgt gatcggcgac gcttcgctta aaaaagcatc
    19441 agcagtggtt tcgcagctat acggtgcata aaaaaatgat ctcatgcaga tgttttgtga
    19501 atgtgtgggt tgacattcat atgaaaaaaa tcataattcc atcatgtttg tgtgggggct
    19561 tttctgtatc ttacgcatcg cactcaagcc tgacagaaaa tatgctgtaa ggctcatatc
    19621 aaaaaccgcc attagctcat caggaagagc agacgacaac caggattgtt gtatggtacg
    19681 gggttcgagg cctcgatggc ggtccaactt ttcataactc ttctgaatca gatcccctta
    19741 ttatcatccc tgcaaagtga aacattgcca ttgtttggct attcaggacg ggtcagagca
    19801 atgaaaaaag cccacacagg ggagagtggg ctgaaatggg aagctaaaga ctcaagtaaa
    19861 cttatcggaa ataaggacca cgcattacgg gggctatcat cgccgatggt cgggatccgg
    19921 caaatcaggt tgattacgta gagagtaaat tatctgctca ccgctgcgtc accccttcgt
    19981 aaatcaggcg tagcgcgaat acaccaataa ttgcaccaat aacccgactg gcaacgcgtt
    20041 gcatacgccc ataagcacga cgcactgcgg gcaaagaaaa cgcctgacta agaaagactc
    20101 gccagataat tgatgcgagc acaatccccg cccaggccat taaacgtgcc catgttggtg
    20161 tttcggcatt taatgttact gagaaaatac taataaaaaa taacacggtt tgcgggttag
    20221 agagatcggt aattaatccg cggcgaaaaa agacatacca gggggcgtta atcggttgtt
    20281 gtagtgtgct catttgcggt gttgactggc ggcgcatgct gcaccacgca aaccataaga
    20341 gataagcgcc gccgacgatt ctgataagcg aaaaaatctc ctcgcactgc gtaattaacg
    20401 tcgccaaacc aaacaaaccc aacccggaat aaaacgcatc gcccagcgcc acgcccagtc
    20461 cggtcagcac ccctgcgcgt cgaccggaag ccaggctggt ttgtactacc acaaagagat
    20521 tggctcccgg attaaaaaaa gtaatcacga acagtcctat ggtcagataa acggcgtgca
    20581 aaggatccat agtgatttca tccataaata agtgaagtaa cttcatcata tttctaccaa
    20641 aaataatcgg gtgcgcgaga gatcacaaag tgtcttattt ccggttactg gcgtttatgc
    20701 cctgagtgaa ctaattatta atcaacccaa taatgtgggt gggtgatagt gtgataacaa
    20761 ctctggagcc gtaatatgaa aataatctct aaaatgttag tcggtgcgtt agcgtttgcc
    20821 gttaccaatg tttatgccgc agaattaatg accaaagcgg aatttgaaaa agttgaatcg
    20881 caatatgaaa aaataggtga tatttcaacc agtaatgaaa tgtcgaccgc agatgcgaaa
    20941 gaagatttga tcaaaaaagc cgatgaaaaa ggggctgatg tgttggtact gacctctggt
    21001 caaactgaca ataagatcca cggcacggca aatatttata agaagaagta attctgaatc
    21061 ctatgtaaac atccccgatg cgtaagttta tcggtgatca tcatctattg aagtttatgc
    21121 cggataaagc gttcgcgctg cattcggcag ttcagctttt cagccgccgc cagaacgtcg
    21181 tccggctgat acctaaataa ttcgccgctg ctgttttatc gccattaaat ttctccagtg
    21241 cctgttgtgg tgtcagtaag cgtggagcgg gagttttcgc cgactcgcgc gccagttccg
    21301 gcagtagcag ctgcaaaaat tgcggcgtta aatccggcgt cggttccaca cttaaaaaca
    21361 gcgccagtcg ctccatcata ttgcgcagtt cacgaatatt tcccggccag tcgtagtgca
    21421 ccagcacggt ttcgcttgcc tgtaacccct ggcgtaatgc ggcagaaaac ggggcggaga
    21481 gcgccgccag agacactttc aaaaagcttt ccgccagcgg cagaatatcc gtcacccgct
    21541 cgcgcagtgg tggcaattgc agacgcaaaa tactcagccg ataaaacaga tcacggcgaa
    21601 actccccttg ccgcatatct tcttccagat tgcagtgagt ggcgctaatg actcgcacat
    21661 ccaccggaac aggctgatgc ccgccgacgc gggtgacctc tttttcttcc agcacccgca
    21721 gcagccgagt ctgcaacggc agcggcattt cgcctatctc gtcaagaaac agcgtgccac
    21781 cgtgggcgat ttcaaacagt ccggcgcgtc ctccgcgtcg agagccggta aacgcccctt
    21841 cctcatagcc aaacagctcc gcttccagca gcgattcggc aatcgccccg cagttgacgg
    21901 caacaaacgg atgcgacttt ttgccctgtc gcgcatcgtg gcgggcaaag tattcccgat
    21961 gaatcgcctg ggctgccagt tctttgcccg tccccgtttc cccctcaatc aacaccgccg
    22021 cactggagcg ggcatacagc aaaatagtct gccgtacctg ttccatctgt ggtgattgac
    22081 cgagcatatc gcccagcacg taacgagtac gcagggcgtt gcgggtggca tcgtgagtgt
    22141 tatgccgtag agacatgcgc gtcatatcca gcgcatcgct gaacgcctgg cgcacggtgg
    22201 cggcggaata gataaaaatt ccggtcattc cggcttcttc tgccagatcg gtaatcagcc
    22261 ctgcgccgac caccgcttcg gtgccgttgg ctttcaactc attgatttgc ccgcgggcgt
    22321 cttcttcggt gatgtaacta cgttggtcga ggcgcaaatt aaaggttttt tgaaatgcta
    22381 ccaatgccgg aatggtttcc tgataggtga caacaccgat agaagaggtg agttttccgg
    22441 cttttgccag tgcctgtaac acatcgtagc cgctcggttt aatcaaaata actggcactg
    22501 acaggcgact tttaagatat gcgccgttag agccagcagc gatgatggcg tcgcaccgtt
    22561 cgttggccag tttcttgcgg atgtaggtca ccgctttttc aaagccaagc tggatagggg
    22621 tgatattcgc caggtgatca aactcgaggc tgatatcgcg aaataactcg aacagccgcg
    22681 ttacagatac cgtccagata accggtttgt cgtcattcag ccgtggtgga tgtgccatag
    22741 cgcaccgcaa agttaagaaa ccgaatattg ggtttagtct tgtttcataa ttgttgcaat
    22801 gaaacgcggt gaaacattgc ctgaaacgtt aactgaaacg catatttgcg gattacttca
    22861 tgactttatc tttaacacat tgaaattaaa tatttaattt tattaaggca attgtggcac
    22921 acccattgct ttgtgtttat caacgcaaat aacaagttga taacaaagga tgggctatgt
    22981 ctctacactc tccaggtaaa gcgtttcgcg ctgcacttag caaagaaacc ccgttgcaaa
    23041 ttgttggcac catcaacgct aaccatgcgc tgctggcgca gcgtgccgga tatcaggcga
    23101 tttatctctc cggcggtggc gtggcggcag gttcgctggg gctgccggat ctcggtattt
    23161 ctacccttga tgatgtgctg actgacattc gtcgtatcac cgacgtttgt tcgttgccgc
    23221 tgctggtcga tgcggatatc ggttttggtt cttcggcttt taacgttgcc cgcacagtga
    23281 aatcgatgat taaagccggg gcggcgggat tgcatattga agatcaggtt ggtgcaaaac
    23341 gctgcggtca tcgtccgaat aaagcgatcg tctcgaaaga agagatggtg gatcggatcc
    23401 gcgcggcggt ggatgcgaaa accgatcctg attttgtgat catggcgcgc accgatgcgc
    23461 tggcggtaga ggggctggat gcggcgatcg agcgtgcgca ggcctatgtt gaagcgggtg
    23521 ccgaaatgct gttcccggag gcgattaccg aactcgccat gtatcgccag tttgccgatg
    23581 cggtgcaggt gccgatcctc gccaacatta ccgaatttgg cgcaacaccg ctttttacca
    23641 ccgacgaatt acgcagcgcc catgtcgcaa tggcgctcta cccgctttca gcgtttcgcg
    23701 ccatgaaccg cgccgctgaa catgtctaca acatcctgcg tcaggaaggc acacagaaaa
    23761 gcgtcatcga caccatgcag acccgcaacg agctgtacga aagcatcaac tactaccagt
    23821 acgaagagaa gctcgacgac ctgtttgccc gtagccaggc gaaataaaac acaacgaaaa
    23881 atatctcgac cctacaaatg acgaggacaa tatgagcgac acaacgatcc tgcaaaacag
    23941 tacccatgtc attaaaccga aaaaatcggt ggcactttcc ggcgttccgg cgggcaatac
    24001 ggcgctctgt accgtgggta aaagcggcaa tgacttgcat taccgtggtt acgatattct
    24061 cgacctcgca gaacattgcg aatttgaaga agtggcgcat ctgctgatcc acggcaaact
    24121 gccgacccgt gacgaactcg ccgcttacaa aacaaaactg aaagccctgc gtggtttacc
    24181 ggctaacgtg cgtaccgtgc tggaagcctt accggcggcg tcacacccga tggatgttat
    24241 gcgcaccggc gtttccgcgc tcggctgcac gctgccagaa aaagaggggc acaccgtttc
    24301 tggcgcgcgc gatattgccg acaaactgct ggcgtcactt agttcgattc ttctctactg
    24361 gtatcactac agccacaacg gcgaacgcat ccagccggaa actgatgacg actctatcgg
    24421 cggtcacttc ctgcatctgc tgcacggcga aaagccgtcg caaagctggg aaaaggcgat
    24481 gcatatttcg ctggtgctgt acgccgaaca cgagtttaac gcttccacct ttaccagccg
    24541 ggtgattgcg ggcactggct ctgatatgta ttccgccatt attggcgcga ttggcgcact
    24601 gcgcgggccg aaacacggcg gggcgaatga agtgtcgctg gagatccagc aacgctacga
    24661 aacgccggac gaagccgaag ctgatatccg caagcgggtg gaaaacaaag aagtagtgat
    24721 tggttttggt catccggttt ataccattgc cgacccgcgc caccaggtga tcaaacgcgt
    24781 ggcaaagcag ctctcgcagg aaggcggctc gctgaagatg tacaacatcg ccgatcgcct
    24841 ggaaacagtg atgtgggaga gcaaaaagat gttccccaat ctcgactggt tctccgctgt
    24901 ttcctacaac atgatgggtg ttcccaccga gatgttcaca ccactgtttg ttatcgcccg
    24961 cgtcactggc tgggcggcgc acattatcga acaacgtcag gacaacaaaa ttatccgtcc
    25021 ttccgccaat tacgttggac cggaagaccg ccagtttgtc gcgctggata agcgccagta
    25081 aacctctacg aataacaata aggaaacgta cccaatgtca gctcaaatca acaacattcg
    25141 cccggaattt gatcgtgaaa tcgttgatat cgtcgattac gtgatgaact acgaaatcag
    25201 ctccagagta gcctacgaca ccgcacatta ctgcctgctc gacacgctcg gctgcggtct
    25261 ggaagctctc gaatatccgg cctgtaaaaa actgctgggg ccaattgtcc ccggcaccgt
    25321 cgtacccaac ggcgtgcgcg ttcccggaac tcagtttcag ctcgaccccg tccaggcggc
    25381 atttaacatt ggcgcgatga tccgttggct cgatttcaac gatacctggc tggcggcgga
    25441 gtgggggcat ccttccgaca acctcggcgg cattctggca acggcggact ggctttcgcg
    25501 caacgcggtc gccagcggca aagcgccgtt gaccatgaaa caggtgctga ccggaatgat
    25561 caaagcccat gaaattcagg gctgcatcgc gctggaaaac tcctttaacc gcgttggtct
    25621 cgaccacgtt ctgttagtga aagtggcttc caccgccgtg gtcgccgaaa tgctcggcct
    25681 gacccgcgag gaaattctca acgccgtttc actggcgtgg gtggacggcc agtcgctgcg
    25741 cacctatcgc catgcgccga acaccggcac gcgtaaatcc tgggcggcgg gcgatgctac
    25801 ttcccgcgcg gtacgtctgg cactgatggc aaaaacgggc gaaatgggtt acccgtcagc
    25861 tctgaccgcg ccggtatggg gcttctacga cgtctccttt aagggtgaat cgttccgctt
    25921 ccagcgccca tacggttctt acgttatgga aaatgtgctg ttcaaaatct ccttcccggc
    25981 agagttccac tcccagacag cagttgaagc ggcgatgacg ctctatgaac agatgcaggc
    26041 agcaggcaaa acggcggcgg atatcgaaaa agtgaccatt cgcacccacg aagcctgtat
    26101 tcgcatcatc gacaaaaaag ggccgctcaa caacccagca gaccgcgacc actgcattca
    26161 gtacatggtg gcgatcccgc tgctgttcgg gcgcttaacg gcggcagatt acgaggacaa
    26221 cgttgcgcaa gataaacgca tcgacaccct gcgcgagaag atcaattgct ttgaagatcc
    26281 ggcgtttacc gctgactacc acgacccgga aaaacgcgcc atcgccaatg ccataaccct
    26341 tgagttcacc gacggcacgc gctttgaaga agtggtggtg gagtacccca ttggtcatgc
    26401 tcgtcgccgc catgacggta ttccgaaact ggtcgataaa ttcaaaatca acctcgcgcg
    26461 ccagttcccg actcgccaac agcagcgcat tctggaggtt tctctcgaca gaactcgcct
    26521 ggaacagatg ccggtcaatg agtatctcga cctgtacgtc atttaagcaa acagcggtaa
    26581 ggcgtaagtt caacaggaga gcattatgtc ttttagcgaa ttttatcagc gttcgattaa
    26641 cgaaccggag aagttctggg ccgagcaggc ccggcgtatt gactggcaga cgccctttac
    26701 gcaaacactc gatcacagca atccgccgtt tgcccgttgg ttttgtgaag gccgaaccaa
    26761 cttgtgtcac aacgctatcg accgctggct ggagaaacag ccagaggcgc tggcgctgat
    26821 tgccgtctct tcggaaacag aagaagagcg cacctttacc tttcgtcagc tgcatgacga
    26881 agtgaacgca gtggcgtcaa tgctgcgctc actgggcgta cggcgtggcg atcgggtgct
    26941 ggtgtatatg ccgatgattg ccgaagcgca tattaccctg ctggcctgcg cgcgcattgg
    27001 cgctattcac tcggtagtgt ttggtggatt tgcctcgcac agcgtggcgg cgcggattga
    27061 tgacgctaaa ccggtgctga ttgtctcggc tgatgccgga gcgcgcggtg gcaaaatcat
    27121 tccttataaa aaattgctcg acgatgcgat aagtcaggcg cagcatcagc cgcgccacgt
    27181 tttactggtg gatcgcgggc tggcgaaaat ggcacgcgtc agcgggcggg atgtcgattt
    27241 cgcgtcgttg cgccatcaac acatcggcgc gcgggtaccg gtggcgtggc tggaatccaa
    27301 cgaaacctcc tgcattctct acacctccgg cacgaccggc aaacctaaag gcgtgcagcg
    27361 tgacgttggc ggatatgcgg tggcgctggc gacctcgatg gacaccattt ttggcggcaa
    27421 agcgggcggt gtgttcttct gtgcgtcgga tatcggctgg gtggtggggc attcgtatat
    27481 cgtctacgcg ccgctgctgg cggggatggc gactatcgtt tacgaaggat taccgacctg
    27541 gccggactgc ggcgtgtggt ggaaaatcgt cgagaaatat caggtgagcc ggatgttctc
    27601 agcgccgacc gccattcgcg tgctgaaaaa attccctacc gctgaaattc gcaaacacga
    27661 tctctcgtcg ctggaagtgc tctatctggc tggagaaccg ctggacgagc cgaccgccag
    27721 ttgggtgagc aatacgctgg atgtgccggt catcgacaac tactggcaga ccgaatccgg
    27781 ctggccgatt atggcgattg ctcgcggtct ggacgacagg ccgacgcgtc tgggaagccc
    27841 cggcgtgccg atgtatggct ataacgtgca gttgcttaat gaagtcaccg gcgaaccgtg
    27901 tggcgtcaac gagaaaggga tgctggtggt ggaagggccg ctgccgccgg ggtgtattca
    27961 gaccatctgg ggcgacgacg accgctttgt gaagacgtac tggtcgctgt tttcccgccc
    28021 ggtgtacgcc acctttgact ggggcatccg tgacgctgac ggttatcact ttattctcgg
    28081 gcgcactgac gatgtaatta acgttgccgg gcatcggctg gggacgcgcg agattgaaga
    28141 gagtatctcc agtcatccgg gcgttgccga agtggcggtg gttggggtga aagatgcgct
    28201 gaaagggcag gtggcagtgg cgtttgtcat tccgaaagag agcgatagtc tggaagatcg
    28261 tgaggtggcg cactcgcaag agaaggcgat tatggcgctg gtggacagcc agattggcaa
    28321 ctttggccgc ccggcgcacg tctggtttgt ctcgcaattg ccgaaaacgc gatccggaaa
    28381 aatgctgcgc cgcacgatcc aggcgatttg cgaaggacgc gatcctggag atctgacgac
    28441 cattgatgat ccagcgtcgt tggatcagat ccgccaggcg atggaagagt aggttattgt
    28501 cggatgcgtc gcctggcgca tccgacacca tgcgccgatg cctgatgcga cgcttaccgc
    28561 gtcttattat gcctacccac tgtttttaca ccgataattt ttcccccacc tttttgcact
    28621 cattcatata aaaaatatat ttccccacga aaacgattgc tttttatctt cagatgaata
    28681 gaatgcggcg gattttttgg gtttcaaaca gcaaaaaggg ggaatttcgt gtcgcaagat
    28741 aacaacttta gccaggggcc agtcccgcag tcggcgcgga aaggggtatt ggcattgacg
    28801 ttcgtcatgc tgggattaac cttcttttcc gccagtatgt ggaccggcgg cactctcgga
    28861 accggtctta gctatcatga tttcttcctc gcagtcctca tcggtaatct tctcctcggt
    28921 atttacactt catttcttgg ttacattggc gcaaaaaccg gcctgaccac tcatcttctt
    28981 gctcgcttct cttttggtgt taaaggctca tggctgcctt cactgctact gggcggaact
    29041 caggttggct ggtttggcgt tggcgtggcg atgtttgcta ttccggtggg caaggcaacc
    29101 gggctggata ttaatttgct gattgccgtc tccggtgtac tgatgaccgt caccgtcttc
    29161 tttggtattt cggcgctgac ggttctttcg gtgattgcag ttccggctat cgcctgcctg
    29221 ggcggttatt ccgtgtggct ggccgttaac ggcatgggcg gcctggaggc attaaaagcg
    29281 gtcgttcccg cacaaccgtt agatttcaat gtcgcgctgg cgctggttgt ggggtcattt
    29341 atcagtgcgg gcacgctcac cgctgacttt gtccggtttg gtcgtaatgc caaactggcg
    29401 gtgctggtgg cgatggtggc ctttttcctc ggcaactcgt tgatgtttat tttcggtgca
    29461 gcgggcgcgg cggcactggg gatggcggat atctctgatg tgatgattgc tcagggtctg
    29521 ctgctgcctg cgattgtggt gctggggcta aatatctgga ccaccaacga taacgcgctc
    29581 tatgcgtcgg gtttaggttt cgccaacatt actggtatgt cgagtaaaac cctttcggtg
    29641 attaacggta ttatcggtac ggtctgcgca ttatggctgt ataacaattt tgtcggctgg
    29701 ctgaccttcc tttcggcagc tattcctcct gtagggggcg tgatcatcgc tgactatctg
    29761 atgaaccgtc gccgctatga gcactttgcg accacgcgta tgatgagtgt caattgggtg
    29821 gcgattctgg ctgtcgcgct ggggattgcc gcaggccact ggttaccggg aattgttccg
    29881 gtcaacgcgg tattaggtgg cgcgctgagc tatctgatcc ttaacccgat tttgaatcgt
    29941 aaaacgacag cagcaatgac gcatgtggag gctaacagtg tcgaataacg ctttacaaac
    30001 aattattaac gcccggttac ccggcaaaga ggggctgtgg cagattcatc ttcacgacgg
    30061 aaaaatcagc gccattgatg tgcaatccgg ggtgatgccc ataactgaaa acagcctgga
    30121 tgccgaacaa ggtttagtta taccgccgtt tgtggagccg catattcacc tggacaccac
    30181 gcaaaccgcc ggacaaccga actggaatca gtccggcacg ctgtttgaag gcattgaacg
    30241 ctgggccgag cgcaaagcgt tattaaccca tgacgatgtg aaacaacgcg cctggcaaac
    30301 gctgaaatgg cagattgcca acggtattca gcatgtgcgt acccatgtcg atgtttcgga
    30361 cgcaacgctg actgcgctga aagcgatgct ggaagtgaag caggaagtcg cgccgtggat
    30421 tgatctgcaa atcgtcgcct tcccgcagga agggattttg tcgtatccca acggtgaagc
    30481 gttgctggaa gaggcgttac gcttaggggc agacgtagtg ggggcgattc cgcattttga
    30541 atttacccgt gaatatggcg tggagtcgct gcataaaacc ttcgccctgg cgcaaaaata
    30601 cgaccgtctc atcgatgttc actgtgatga gattgatgac gaacagtcgc gctttgttga
    30661 aaccgttgct gccctggcgc accgtgaagg catgggcgcg cgagtcaccg ccagccacac
    30721 tacggcaatg cactcctata acggggcgta tacctcgcgc ctgttccgct tgctgaaaat
    30781 gtccggtatt aactttgtcg ccaacccgct ggtcaatatc catctgcaag gacgtttcga
    30841 tacctatcca aaacgtcgcg gcatcacgcg cgttaaagag atgctggagt ccggcattaa
    30901 cgtctgcttt ggtcacgatg atgtcttcga tccgtggtat ccactgggaa cggcgaatat
    30961 gctgcaagtg ctgcatatgg ggctgcatgt ttgccagctg atgggctacg ggcagattaa
    31021 cgatggcctg aatttaatca cccaccacag tgccaggacg ttgaatttgc aggattacgg
    31081 cattgccgcc ggaaacagcg ccaacctgat tatcctgccg gctgaaaatg ggtttgacgc
    31141 gctgcgccgt caggttccgg tgcgctattc ggtacgtggc ggtaaggtga ttgccagcac
    31201 ccaaccagca caaaccaccg tatatctgga gcagccagaa gccatcgatt acaaacggta
    31261 atttcctctg cgttgaagag ccactgacct gtgtcagtgg ctaccgtgat tcatgcccgc
    31321 caacatccgc acattcttcc aacgccatgt gtaaaaatgc cttcgcggcg gctgtctgcc
    31381 agctattttt ccgccgcaac aaaaccgccg ttctctccag taacggtggg gcaagggata
    31441 tagctttaag cccgtcatgt tgtgtggcaa tcgctgctgg caacaatgtg gaaagggaag
    31501 tgcggcgaat cagctccaga accgcgctaa ttgagttcgc ctcaatgacc acctgtggat
    31561 gtagccccgc tttctcgcag tagtggtcaa tttgctctct ggtggcaaat tccgcgctga
    31621 gcaggaccag tttttcatca tgcaagcgac tcaacgccac ctgttcacag gcagccagcg
    31681 gatgatgttg cgccacgact aacgctaaac tttctgtcag taaaggaatt gcctccagct
    31741 ccggcgaatg cacaggcgcg aaggcaatcc caacgtccaa ctcgtcgcga caaagcagat
    31801 cttcgatttt ctcctgcgac atttcctgta gctggagcgt gatgccgggg tagcgcgcat
    31861 agaaatccgc cattaaaggg ccgataaagt agcttgtaaa ggtgggagtg acggcgatac
    31921 gcagcaatcc tcgcgtcaga tcggcaacat catgaatcgc ccgtttaccc gcccccagtt
    31981 cctgtaacgc ccggctggcg tactgtcgcc agacttctcc tgcatcagtg agacgaatcg
    32041 ttcgcccgct acggtcaaac agcggcacgc ctaaactctc ctctaactgg cgaatctgct
    32101 gggaaagcgc aggctgggag acgtgcaacg cactggcggc acgggtaaag ctgccatgtt
    32161 cagccacggc aagaaaataa ttgatatgtc gagagagcat tcgccaacct ataagtaaat
    32221 ccaatagaac tcatcataaa tgagactttt accttatgac aatcggcgag tagtctgcct
    32281 ctcattccag agacagacag aggttaacgg tgaaagagat tattgatgga ttccttaaat
    32341 tccagcgcga ggcatttccg aagcgggaag ccttgtttaa acagctggcg acacagcaaa
    32401 gcccgcgcac cctttttatc tcctgctccg acagccgtct ggtccctgag ctggtgacgc
    32461 aacgtgagcc tggcgatctg ttcgttattc gcaacgcggg caatatcgtt ccttcctacg
    32521 ggccagaacc cggtggcgtt tctgcttcgg tggagtacgc cgtcgctgcg cttcgggtat
    32581 ctgacattgt gatttgcggt cattccaact gcggcgcgat gacctccatt gccagctgtc
    32641 agtgcatgga ccatatgcct gccgtttccc actggctgcg ttatgccgat tcagcccgcg
    32701 tcgttaatga ggcgcgcccg catcccgatt taccgtcaaa agctgcggcg atggtacgtg
    32761 aaaacgtcat tgctcagttg gctaatttgc aaactcatcc atcggtgcgc ctggcgctcg
    32821 aagaggggcg gatcgccctg cacggctggg tctacgacat tgcaagcggc agcatcgcag
    32881 cttttgacgg cgcaacccgc cagtttgtgc cactggccgc taatcctcga gtttgtgcca
    32941 taccgctacg ccaaccgacc gcagcgtaac cttattttta aaccatcagg agatccacca
    33001 tgattcagtc gcaaattaac cgcaatattc gtcttgatct tgccgatgcc attttgctca
    33061 gcaaagctaa aaaagatctc tcatttgccg agattgccga cggcaccggt ctggcagaag
    33121 ccttcgtaac cgcggctttg ctgggtcagc aggcgcttcc tgccgacgcc gcccgcctgg
    33181 tcggggcgaa gctggatctc gacgaagacg ctattctact gttgcagatg attccactgc
    33241 gtggctgcat tgatgaccgt attccaaccg acccaacgat gtatcgtttc tatgaaatgt
    33301 tgcaggtgta cggcacaacc ctgaaagcgt tggttcatga gaagtttggc gatggcatta
    33361 tcagcgcgat taacttcaaa ctcgacgtta agaaagtggc ggacccggaa ggtggcgaac
    33421 gtgcggtcat caccttagat ggtaaatatc tgccgaccaa accgttctga cagccatgcg
    33481 taaccatcaa aagacgttca cgatgctgct ggttctggtg ctgattggtc ttaatatgcg
    33541 accactgctc acctccgtcg ggccactgct accgcaattg cgccaggcaa gcggaatgag
    33601 ctttagcgtg gctgccctgt tgaccgctct gccggtggtt accatgggcg ggctggcgct
    33661 ggccggaagc tggcttcatc agcatgtcag cgaacgtcgc agcgtcgcca tcagtttgtt
    33721 actgattgcc gtcggtgcat tgatgcgtga gctttacccc caaagtgcgc tgctgcttag
    33781 cagcgtactg cttggtggag tggggatcgg catcattcag gcagtgatgc cttcggtaat
    33841 taagcggcgg tttcagcacc gtacgccact ggtgatgggg ctgtggtccg cggctctgat
    33901 gggcggcggt ggacttggtg ccgccattac gccctggtta gttcaacata gcgaaacctg
    33961 gtatcaaaca ctcgcctggt gggcgctgcc tgccgttgtt gcgctctttg cctggtggtg
    34021 gcaaaacgcc cgcgaggtcg cctcttctca caagacaaca accactccgg ttcgcgtggt
    34081 atttactccc cgcgcgtgga cgctgggtgt ttacttcggt ctgattaacg gtggttacgc
    34141 cagcctgatt gcctggttac ccgctttcta tattgagatt ggtgccagcg cgcagtacag
    34201 cggttccttg ctggcattga tgacgcttgg gcaagcagca ggggcattgc tgatgcctgc
    34261 tatggctcgc catcaggatc ggcggaaact tttgatgctg gcgctggcgt tacaactggt
    34321 ggggttctgc ggctttatct ggctgccgct gcaattgccg gtcttctggg caatggtgtg
    34381 tgggttaggt ctgggcggcg catttccgct ctgtttgctg ctggcgctcg atcactctgc
    34441 gcaaccggct attgctggca aactggtggc gtttatgcag gggatcggtt ttatcatcgc
    34501 cgggcttgct ccctggtttt ctggtgtgct gcgtagtatc agtggcaatt acttgatgga
    34561 ctgggcgttt catgcgctgt gcgtcgttgg gctgatgatc ataaccctgc gttttgcacc
    34621 agcacgtttt ccgcagctgt gggtcaaaga ggcatgatgc gacgcttgtt tcgccagata
    34681 atggaagagt gaattattgt cggatgtgcc caatggcgca tccgacattt atttcagtgc
    34741 ttatttaaac tgaaggt
//
LOCUS       DADXDL010000053        34738 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.053, whole genome shotgun sequence.
ACCESSION   DADXDL010000053 DADXDL010000000
VERSION     DADXDL010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34738)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34738)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34738
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.053"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(106..1698)
                     /gene="lsrK"
                     /locus_tag="IRB70_002823"
     CDS             complement(106..1698)
                     /gene="lsrK"
                     /locus_tag="IRB70_002823"
                     /EC_number="2.7.1.189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416028.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer-2 kinase"
                     /protein_id="HBC0632713.1"
                     /translation="MARLFTPSESKYYLMALDAGTGSIRAVIFDLEGNQIAVRQAEWR
                     HLAVPDVPGSMEFDLNKNWQLACECMRQALHNAGIAPEYIAAVSACSMREGIVLYNND
                     GTPIWACANVDARAAREVSELKELHNNTFENKVYRATGQTLALSAIPRLLWLAHHRSD
                     IYRQASTITMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADIL
                     SPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQTAVLGGTF
                     WQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTMRWFRDAFCAEEKLIAE
                     RLGIDTYTLLEEMASRVPPGSWGVMPIFSDRMRFKTWYHAAPSFINLSIDPDKCNKAT
                     LFRALEENAAIVSACNLQQIADFSNIHPTSLVFAGGGSKGKLWSQILADVSGLPVNIP
                     VVKEATALGCAIAAGVGAGIFSSMAETGERLVRWERTHTPDPEKHELYQDSRDKWQAV
                     YQDQLGLVDHGLTTSLWKAPGL"
     gene            complement(1777..2730)
                     /gene="lsrR"
                     /locus_tag="IRB70_002824"
     CDS             complement(1777..2730)
                     /gene="lsrR"
                     /locus_tag="IRB70_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LsrR"
                     /protein_id="HBC0632714.1"
                     /translation="MTINDSVISEQGMCEEEQVARIAWFYYHDGLTQSEISDRLGLTR
                     LKVSRLLEKGHQSGIIRVQINSRFEGCLEYETQLRRQFSLQHVRVIPGLADADVGGRL
                     GIGAAHMLMSLLQPQQMLAIGFGEATMNTLQRLSGFISSQQIRLVTLSGGVGSYMTGI
                     GQLNAACSVNIIPAPLRASSADIARTLKNENCVKDVLLAAQAADVAIVGIGAVSQQDD
                     ATIIRSGYISQGEQLMIGRKGAVGDILGYFFDAKGDVVTDIKIHNELIGLPLSALKTI
                     PVRVGVAGGENKAEAIAAAMKGGYINALVTDQDTAAAILRS"
     gene            2979..4514
                     /gene="lsrA"
                     /locus_tag="IRB70_002825"
     CDS             2979..4514
                     /gene="lsrA"
                     /locus_tag="IRB70_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter ATP-binding
                     protein LsrA"
                     /protein_id="HBC0632715.1"
                     /translation="MQTSDTRALPLLCARSVYKQYSGVNVLKGIDFTLHQGEVHALLG
                     GNGAGKSTLMKIIAGITPADSGTLEIGGNNYVRLTPVHAHQLGIYLVPQEPLLFPSLS
                     IKENILFGLAKKQLSIQKMNNLLAALGCQFDLHSLAGSLDVADRQMVEILRGLMRDSR
                     ILILDEPTASLTPAETERLFIRLRELLATGVGIVFISHKLPEIRQIADRISVMRDGTI
                     ALSGKTSELSTDDIIQAITPALREKSLSASQKLWLELPGNRPQHAAGTPVLTLENLTG
                     EGFRNVSLTLNAGEILGLAGLVGAGRTELAETLYGLRTLRGGRIMLNGKEINRLSTGE
                     RLLRGLVYLPEDRQSSGLNLDASLAWNVCALTHNLRGFWAKTAKDNATLERYRRALNI
                     KFNQPEQAARTLSGGNQQKILIAKCLEASPQVLIVDEPTRGVDVSARNDIYQLLRSIA
                     AQNVAVLLISSDLEEIELMADRVYVMHQGEIAHSALTGRDINVETIMRVAFGDSQRQE
                     ASC"
     gene            4508..5536
                     /gene="lsrC"
                     /locus_tag="IRB70_002826"
     CDS             4508..5536
                     /gene="lsrC"
                     /locus_tag="IRB70_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrC"
                     /protein_id="HBC0632716.1"
                     /translation="MLKFIQNNREITALLAVVLLFVLPGFLDRQYLSVQTLTMVYSSA
                     QILILLAMGATLVMLTRNIDVSVGSITGMCAVLLGMLLNAGYSLPVACVATLLLGLLA
                     GFFNGVLVAWLKIPAIVATLGTLGLYRGIMLLWTGGKWIEGLPTELKQLSAPLLFGVS
                     AIGWLTIILVAFMAWLLAKTAFGRSFYVTGDNLQGARQLGVRTEAIRIVAFSLNGCMA
                     ALAGIVFASQIGFIPNQTGTGLEMKAIAACVLGGISLLGGSGAIIGAVLGAWFLTQID
                     SVLVLLRIPAWWNDFIAGMVLLAVLVFDGRLRCALERNLRRQKYARFMMPPPSVKPAS
                     SGKKREAA"
     gene            5536..6528
                     /gene="lsrD"
                     /locus_tag="IRB70_002827"
     CDS             5536..6528
                     /gene="lsrD"
                     /locus_tag="IRB70_002827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter permease LsrD"
                     /protein_id="HBC0632717.1"
                     /translation="MRIRYGWELALAALLVIEIVAFGAINPRMLDLNMLLFSTSDFIC
                     IGIVALPLTMVIVSGGIDISFGSTIGLCAIALGVLFQSGVPMPLAILLTLLLGALCGL
                     INAGLIIYTKVNPLVITLGTLYLFAGSALLLSGMAGATGYEGIGGFPMAFTDFANLDV
                     LGLPVPLIIFLICLLVFWLWLHKTHAGRNVFLIGQSPRVAVYSAIPVNRTLCALYAMT
                     GLASAVAAVLLVSYFGSARSDLGASFLMPAITAVVLGGANIYGGSGSIIGTAIAVLLV
                     GYLQQGLQMAGVPNQVSSALSGALLIVVVVGRSVSLHRQQIKEWLARRANNPLP"
     gene            6540..7562
                     /gene="lsrB"
                     /locus_tag="IRB70_002828"
     CDS             6540..7562
                     /gene="lsrB"
                     /locus_tag="IRB70_002828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autoinducer 2 ABC transporter substrate-binding
                     protein LsrB"
                     /protein_id="HBC0632718.1"
                     /translation="MTLHRFKKIALLSALGIAVISMNVQAAERIAFIPKLVGVGFFTS
                     GGNGAQQAGKELGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIIVSAVSPDGLCPAL
                     KRAMQRGVRVLTWDSDTKPECRSYYINQGTPAQLGGMLVDMAARQVNKDKAKVAFFYS
                     SPTVTDQNQWVKEAKAKIAKEHPGWEIVTTQFGYNDATKSLQTAEGILKAYSDLDAII
                     APDANALPAAAQAAENLKNDKVAIVGFSTPNVMRPYVERGTVKEFGLWDVVQQGKISV
                     YVADALLKKGSMKTGDKLDIQGVGQVEVSPNSVQGYDYEADGNGIVLLPERVIFNKEN
                     IGKYDF"
     gene            7589..8464
                     /gene="lsrF"
                     /locus_tag="IRB70_002829"
     CDS             7589..8464
                     /gene="lsrF"
                     /locus_tag="IRB70_002829"
                     /EC_number="2.3.1.245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxy-5-phosphonooxypentane-2,4-dione
                     thiolase"
                     /protein_id="HBC0632719.1"
                     /translation="MADLDDIKDGKDFRTDQPQQNIPFILKGCGALDWGMQSRLSRIF
                     DPKTGKTVMLAFDHGYFQGPTTGLERIDINIAPLFEHADVLMCTRGILRSVVPPATNK
                     PVVLRASGANSILAELSNEAVALSMDDAVRLNSCAVAAQVYIGSEYEHQSIKNIIQLV
                     DAGMKVGMPTMAVTGVGKDMVRDQRYFSLATRIAAEMGAQIIKTYYVDKGFERIVAGC
                     PVPIVIAGGKKLPEREALEMCWQAIDQGASGVDMGRNIFQSDHPVAMMKAVQAVVHHN
                     ETADRAYELYLSEKQ"
     gene            8488..8778
                     /gene="lsrG"
                     /locus_tag="IRB70_002830"
     CDS             8488..8778
                     /gene="lsrG"
                     /locus_tag="IRB70_002830"
                     /EC_number="5.3.1.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(4S)-4-hydroxy-5-phosphonooxypentane-2,3-dione
                     isomerase"
                     /protein_id="HBC0632720.1"
                     /translation="MHVTLVEINVHEDKVDEFIEVFRQNHLGSVQEEGNLRFDVLQDP
                     EVNSRFYIYEAYKDEDAVAFHKTTPHYKTCVAKLEALMTGPRKKRLFNGLMP"
     gene            8835..9593
                     /gene="tam"
                     /locus_tag="IRB70_002831"
     CDS             8835..9593
                     /gene="tam"
                     /locus_tag="IRB70_002831"
                     /EC_number="2.1.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trans-aconitate 2-methyltransferase"
                     /protein_id="HBC0632721.1"
                     /translation="MSDWNPSLYLHFAAERSRPAMELLARVPLENIEYVADLGCGPGN
                     STALLHQRWPAARITGIDSSPAMIAEARSALPDCQFVEADIRNWQPEQALDLIFANAS
                     LQWLPAHYELFPHLVSLLNSHGVLAVQMPDNWLEPTHVLMREVAWEQNYPDRGREPLA
                     GVHAYYDILSEAGCEVDIWRTTYYHQMPSHQAIIDWVTATGLRPWLQDLTESEQQHFL
                     TRYHQMLEEQYPLQENGEILLAFPRLFIVARRTE"
     gene            complement(9597..10511)
                     /locus_tag="IRB70_002832"
     CDS             complement(9597..10511)
                     /locus_tag="IRB70_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416037.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bestrophin family protein"
                     /protein_id="HBC0632722.1"
                     /translation="MIVRPQQHWLRRIFVWHGSVLSKISSRLLLNFLFSIAVIFMLPW
                     YTHLGIKFTLAPFSILGVAIAIFLGFRNNAGYARYVEARKLWGQLMIASRSLLREVKT
                     TLPDSASVREFARLQIAFAHCLRMTLRKQPQAEVLAQYLKTEDLQRVLTSNSPANRIL
                     LIMGEWLAVQRRNGQLSDILFISLNDRLNDISAVLAGCERIAYTPIPFAYTLILHRTV
                     YLFCIMLPFALVVDLHYMTPFISVLISYTFISLDCLAEELEDPFGIENNDLPLDAICN
                     AIEIDLLQMNDEAEIPAKILPDRHYQLT"
     gene            complement(10708..12159)
                     /gene="uxaB"
                     /locus_tag="IRB70_002833"
     CDS             complement(10708..12159)
                     /gene="uxaB"
                     /locus_tag="IRB70_002833"
                     /EC_number="1.1.1.58"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBC0632723.1"
                     /translation="MKTLNRRDFPGAQYPERIIQFGEGNFLRAFVDWQIDLLNEHTDL
                     NSGVVVVRPIETSFPPSLSTQDGLYTTIIRGLNEKGEAVSDARLIRSVNREISVYSEY
                     DEFLKLAHNPEMRFVFSNTTEAGISYHAGDKFDDAPAVSYPAKLTRLLFERFSHFNGA
                     QDKGWIIIPCELIDYNGDALRELVLRYAQEWALPEAFIQWLDQANSFCSTLVDRIVTG
                     YPRDEVAKLEEELGYHDGFLDTAEHFYLFVIQGPKSLATELRLDKYPLNVLIVDDIKP
                     YKERKVAILNGAHTALVPVAFQAGLDTVGEAMNDAEICAFVEKAIYEEIIPVLDLPRD
                     ELESFASAVTGRFRNPYIKHQLLSIALNGMTKFRTRILPQLLAGQKANGTLPARLTFA
                     LAALIAFYRGERNGETYPVQDDAHWLERYQQLWSQHRNRVIGTQELVAIVLAEKDHWE
                     QDLTQVPGLVEQVANDLDAILEKGMREAVRPLC"
     gene            complement(12387..13805)
                     /locus_tag="IRB70_002834"
     CDS             complement(12387..13805)
                     /locus_tag="IRB70_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase"
                     /protein_id="HBC0632724.1"
                     /translation="MHVHPISTFRLFQEGHLLRNSIAIFALTTLFYFIGAELRLVHEL
                     SLFWPLNGVMAGVFARYVWLNRLHYYAISYVAMLVYDAITTEWGLVSLAINFSNMMFI
                     VTVALLVVRDKRLGKNKYEPVSALRLFNYCLIAALLCAIVGAIGSVSIDSLDFWPLLA
                     DWFSEQFSTGVLIVPCMLTLAIPGVLPRFKAEQMMPAIALIVSVIASVVIGGAGSLAF
                     PLPALIWCAVRYTPQVTCLLTFVTGAVEIVLVANSVIDISVGSPFSIPEMFSARLGIA
                     TMAICPIMVSFSVAAINSLMKQVALRADFDFLTQVYSRSGLYEALKSPSLKQTQHLTV
                     MLLDIDYFKSINDNYGHECGDKVLSVFAQHIQKIVGDKGLVARMGGEEFAVAVPSVNP
                     VDGLLMAEKIRKGVELQPFTWQQKTLYLTVSIGVGSGCASYRTLTDDFNKLMVEADTC
                     LYRSKKDGRNRTSTMRYGEEVV"
     gene            complement(13944..14303)
                     /locus_tag="IRB70_002835"
     CDS             complement(13944..14303)
                     /locus_tag="IRB70_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4186 domain-containing protein"
                     /protein_id="HBC0632725.1"
                     /translation="MQSLDPLFARLSRSKFRSRFRLGMKERQYCLEKGAPVIEQHAAD
                     FVAKRLAPALPANDGKQTPMRGHPVFIAQHATATCCRGCLAKWHNIPQGEALSEEQQR
                     YIVTVIYHWLVIQMNQP"
     gene            complement(14303..15229)
                     /gene="glsB"
                     /locus_tag="IRB70_002836"
     CDS             complement(14303..15229)
                     /gene="glsB"
                     /locus_tag="IRB70_002836"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase B"
                     /protein_id="HBC0632726.1"
                     /translation="MAVAMDNAILENILRQVRPLIGQGKVADYIPALATVDGSRLGIA
                     ICTVDGQLFQAGDAQERFSIQSISKVLSLVVAMRHYSEEEIWQRVGKDPSGSPFNSLV
                     QLEMEQGIPRNPFINAGALVVCDMLQGRLSAPRQRMLEVVRGLSGVSDISYDTVVARS
                     EFEHSARNAAIAWLMKSFGNFHHDVTTVLQNYFHYCALKMSCVELARTFVFLANQGKA
                     IHIDEPVVTPMQARQINALMATSGMYQNAGEFAWRVGLPAKSGVGGGIVAIVPHEMAI
                     AVWSPELDDAGNSLAGIAVLEQLTKQLGRSVY"
     gene            complement(15293..16681)
                     /gene="sad"
                     /locus_tag="IRB70_002837"
     CDS             complement(15293..16681)
                     /gene="sad"
                     /locus_tag="IRB70_002837"
                     /EC_number="1.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate-semialdehyde dehydrogenase"
                     /protein_id="HBC0632727.1"
                     /translation="MTITPATHAISINPATGEQLSVLPWAGADDIENALQLAAAGFRD
                     WRETNIDYRAEKLRDIGKALRVRSEEMAQMITREMGKPINQARAEVAKSANLCDWYAE
                     HGPAMLKAEPTLVENQQAVIEYRPLGTILAIMPWNFPLWQVMRGAVPIILAGNGYLLK
                     HAPNVMGCAQLIAQVFKDAGIPQGVYGWLNADNDGVSQMIKDSRIAAVTVTGSVRAGA
                     AIGAQAGAALKKCVLELGGSDPFIVLNDADLELAVKAAVAGRYQNTGQVCAAAKRFII
                     EEGIASAFTERFVAAAAALKMGDPRDEENTLGPMARFDLRDELHHQVEKTLAQGARLL
                     LGGEKMAGAGNYYPPTVLANVTPEMTAFREEMFGPVAAITIAKDAEHALELANNSEFG
                     LSATIFTTDETRARQMAARLECGGVFINGYCASDARVAFGGVKKSGFGRELSHFGLHE
                     FCNIQTVWKDRV"
     gene            16782..17663
                     /locus_tag="IRB70_002838"
     CDS             16782..17663
                     /locus_tag="IRB70_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0632728.1"
                     /translation="MDLTQLEMFNAVAEAGSITQAAAKVHRVPSNLTTRLRQLETELG
                     VDLFIRENQRLRLSPAGHNFLRYSQQILALVDEARSVVAGDEPQGLFSLGSLESTAAV
                     RIPATLAEFNRRYPKIQFSLSTGPSGTMLEGVLEGKLNAAFIDGPINHTAIDGIPVYR
                     EELMIVTPQGHAPVTRASQVNGSNIYAFRANCSYRRHFESWFHADGAAPGTIHEMESY
                     HGMLACVVAGAGIALIPRSMLESMPGHHQVEAWPLAEQWRWLTTWLVWRRGAKTRPLE
                     AFIQLLDAPDSAKQGYQ"
     gene            17741..18856
                     /gene="yneK"
                     /locus_tag="IRB70_002839"
     CDS             17741..18856
                     /gene="yneK"
                     /locus_tag="IRB70_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative protein YneK"
                     /protein_id="HBC0632729.1"
                     /translation="MVTPVSISNYISLPDDFPVRNIAPQVKEVLKDFIDALSTIICDE
                     EWRTSLNINSATKKIFNNLDNLSYIQRTSFRGNDTLYNEKVQFKLTYPVKNGRHKENI
                     EFQVVINLSPIYLDNFRHDGEINIFCAPNPKPVTMGRVFQTGVERVLFLFLNDFIEQF
                     PIINPGVPIKRAHTPHIEPLHPDHHTAADYIRQFDLLVLNFISRGNFVILPRLWNNSE
                     VHRWFGNKEPNLLTAILDITDSELKEDLLQSLMDSLGSNKHVLPEVCICFLSLLAEQD
                     FPHFQELFLFFANMLLHYHQFMKPNESDLIDVLMPASLSDDKIIKHMARKTLKLFVKN
                     ETPPKVTHEDLVKNRPRSPVRPPIPATSKTPDLPERH"
     gene            19006..20196
                     /gene="ydeA"
                     /locus_tag="IRB70_002840"
     CDS             19006..20196
                     /gene="ydeA"
                     /locus_tag="IRB70_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose MFS transporter"
                     /protein_id="HBC0632730.1"
                     /translation="MTTNTVSRKVAWLRVVTLAVAAFIFNTTEFVPVGLLSDIAQSFH
                     MQTAQVGIMLTIYAWVVALMSLPFMLMTSQVERRKLLICLFVVFIASHVLSFLSWSFT
                     VLVISRIGVAFAHAIFWSITASLAIRMAPAGKRAQALSLIATGTALAMVLGLPLGRIV
                     GQYFGWRMTFFAIGIGALITLLCLIKLLPLLPSEHSGSLKSLPLLFRRPALMSIYLLT
                     VVVVTAHYTAYSYIEPFVQNIAGFSANFATALLLLLGGAGIIGSVIFGKLGNQYASAL
                     VSTAIALLLVCLALLLPAANSEIHLGVLSIFWGIAMMIIGLGMQVKVLALAPDATDVA
                     MALFSGIFNIGIGAGALVGNQVSLHWSMSMIGYVGAVPAFAALIWSIIIFRRWPVTLE
                     EQTQ"
     gene            complement(20221..20886)
                     /gene="marC"
                     /locus_tag="IRB70_002841"
     CDS             complement(20221..20886)
                     /gene="marC"
                     /locus_tag="IRB70_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter MarC"
                     /protein_id="HBC0632731.1"
                     /translation="MLDLFKAIGLGLVVLLPLANPLTTVALFLGLAGNMNSAERNRQS
                     LMASVYVFAIMMVAYYAGQLVMDTFGISIPGLRIAGGLIVAFIGFRMLFPQQKAIDSP
                     EAKSKSEELEDEPSANIAFVPLAMPSTAGPGTIAMIISSASTVRQSSTFADWVLMVAP
                     PLIFFLVAVILWGSLRSSGAIMRLVGKGGIEAISRLMGFLLVCMGVQFIINGILEIIK
                     TYH"
     gene            21098..21532
                     /gene="marR"
                     /locus_tag="IRB70_002842"
     CDS             21098..21532
                     /gene="marR"
                     /locus_tag="IRB70_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310164.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance transcriptional
                     regulator MarR"
                     /protein_id="HBC0632732.1"
                     /translation="MKSTSDLFNEIIPLGRLIHMVNQKKDRLLNEYLSPLDITAAQFK
                     VLCSIRCAECITPVELKKVLSVDLGALTRMLDRLVCKGWVERLPNPNDKRGVLVKLTT
                     SGAAICEQCHQLVGQDLHQELTKNLTADEVATLEHLLKKVLP"
     gene            21553..21936
                     /gene="marA"
                     /locus_tag="IRB70_002843"
     CDS             21553..21936
                     /gene="marA"
                     /locus_tag="IRB70_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707445.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MDR efflux pump AcrAB transcriptional activator
                     MarA"
                     /protein_id="HBC0632733.1"
                     /translation="MSRRNTDAITIHSILDWIEDNLESPLSLEKVSERSGYSKWHLQR
                     MFKKETGHSLGQYIRSRKMTEIAQKLKESNEPILYLAERYGFESQQTLTRTFKNYFDV
                     PPHKYRMTNMQGESRFLHPLNHYNS"
     gene            21968..22186
                     /gene="marB"
                     /locus_tag="IRB70_002844"
     CDS             21968..22186
                     /gene="marB"
                     /locus_tag="IRB70_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multiple antibiotic resistance protein MarB"
                     /protein_id="HBC0632734.1"
                     /translation="MKPLLSAIAAALILFSAQGVAEQTTQQFVTSCANVVVVPPSQEQ
                     PPFDLNHMGTGSDKSDALGVPYYNQHAM"
     gene            complement(22217..23116)
                     /gene="eamA"
                     /locus_tag="IRB70_002845"
     CDS             complement(22217..23116)
                     /gene="eamA"
                     /locus_tag="IRB70_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416050.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetylserine/cysteine exporter"
                     /protein_id="HBC0632735.1"
                     /translation="MSRKDGVLALLVVVVWGLNFVVIKVGLHNMPPLMLAGLRFMLVA
                     FPAIFFVARPKVPLNLLLGYGLTISFAQFAFLFCAINFGMPAGLASLVLQAQAFFTIV
                     LGAFTFGERLHGKQLAGIALAIFGVLVLIEDSLNGQHVAMLGFMLTLAAAFSWACGNI
                     FNKKIMSHATRPAVMSLVIWSALIPIIPFFVASLILDGSATMIHSLVTIDMTTILSLM
                     YLAFVATIVGYGIWGTLLGRYETWRVAPLSLLVPVVGLASAALLLDERLTGLQFFGAV
                     LIMTGLYINVFGLRWRKAVKVGS"
     gene            23311..24498
                     /gene="ydeE"
                     /locus_tag="IRB70_002846"
     CDS             23311..24498
                     /gene="ydeE"
                     /locus_tag="IRB70_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="efflux MFS transporter YdeE"
                     /protein_id="HBC0632736.1"
                     /translation="MNLSLRRSTSALLASSLLLTIGRGATLPFMTIYLSRQYSLSVDL
                     IGYAMTIALTIGVVFSLGFGILADKFDKKRYMLLAITAFASGFIAIPLVNNVTLVVLF
                     FALINCAYSVFATVLKAWFADNLSSTSKTKIFSINYTMLNIGWTIGPPLGTLLVMQSI
                     NLPFWLAAICSAFPMLFIQIWVKRSEKIIATETGSAWSPKVLLQDKALLWFTCSGFLA
                     SFVSGAFASCISQYVMVIADGDFAEKVVAVVLPVNAAMVVTLQYSVGRRLNPANIRAL
                     MTAGTLCFVIGLVGFIFSGNSLLMWGMSAAVFTVGEIIYAPGEYMLIDHIAPPGMKAS
                     YFSAQSLGWLGAAINPLVSGIVLTSLPPFSLFIILALVIVAAWVLMLKGIRARPWGQP
                     ALC"
     gene            24625..24720
                     /gene="mgtS"
                     /locus_tag="IRB70_002847"
     CDS             24625..24720
                     /gene="mgtS"
                     /locus_tag="IRB70_002847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein MgtS"
                     /protein_id="HBC0632737.1"
                     /translation="MLGNMNVFMAVLGIILFSGFLAAYFSHKWDD"
     gene            complement(24939..25829)
                     /gene="dgcZ"
                     /locus_tag="IRB70_002848"
     CDS             complement(24939..25829)
                     /gene="dgcZ"
                     /locus_tag="IRB70_002848"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcZ"
                     /protein_id="HBC0632738.1"
                     /translation="MIKKTTEIDAILLNLNKAIDAHYQWLVSMFHSVVARDASKPEIT
                     DNHSYGLCQFGRWIDHLGPLDNDELPYVRLMDSAHQHMHNCGRELMLAIVENHWQDAH
                     FDAFQEGLLSFTAALTDYKIYLLTIRSNMDVLTGLPGRRVLDESFDHQLRNAEPLNLY
                     LMLLDIDRFKLVNDTYGHLIGDVVLRTLATYLASWTRDYETVYRYGGEEFIIIVKADN
                     DEEACRAGIRICQLVDNHAITHSEGHINITVTAGVSRAFPEEPLDVVIGRADRAMYEG
                     KQTGRNRCMFIDEQNVIHRV"
     gene            complement(26084..26476)
                     /gene="ydeI"
                     /locus_tag="IRB70_002849"
     CDS             complement(26084..26476)
                     /gene="ydeI"
                     /locus_tag="IRB70_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdeI family stress tolerance OB fold protein"
                     /protein_id="HBC0632739.1"
                     /translation="MKFQAIVLASFLVMPYALADDPGGLKQDAAPPPPHAIEDGYRGT
                     DDAKKMTVDFAKTMHDGASVSLRGNLISHKGEDRYVFRDKSGEINVVIPAAVFDGREV
                     QPDQMINISGSLDKKSAPAVVRVTQLQK"
     gene            complement(26842..28887)
                     /gene="dcp"
                     /locus_tag="IRB70_002850"
     CDS             complement(26842..28887)
                     /gene="dcp"
                     /locus_tag="IRB70_002850"
                     /EC_number="3.4.15.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-dipeptidase Dcp"
                     /protein_id="HBC0632740.1"
                     /translation="MTTMNPFLVQSTLPYLAPHFDQIANHHYRPAFDEGMQQKRAEIA
                     AIALNPQTPDFNNTILALEQSGELLTRVTSVFFAMTAAHTNDELQRLDEQFSAELAEL
                     ANDIYLNGELFARVDAVWQRRESLGLDSESIRLVEVIHQRFVLAGAKLKQADKAKLKV
                     LNTEAATLTSQFNQRLLAANKSGGLVVNDIAQLAGMSEQEIALAAEAAREKGLYNKWL
                     IPLLNTTQQPALAELCDRATREKLFTAGWMRAEKNDANDTRAIIQRLVEIRAQQAKLL
                     GFPHYAAWKIADQMAKTPEAALNFMREIVPAARQRASDELASIQAVIDKQQGGFSAQP
                     WDWAFYAEQVRREKFDLDESQLKPYFELNTVLNEGVFWTANQLFGIKFVERFDIPVYH
                     PDVRVWEIFDHNGVGLALFYGDFFARDSKSGGAWMGNFVEQSTLNETHPVIYNVCNYQ
                     KPAAGEPALLLWDDVITLFHEFGHTLHGLFACQRYATLSGTNTPRDFVEFPSQINEHW
                     ATHPQVFARYARHYQSGAAMPDELQQKMRNASLFNKGYEMSELLSAALLDMRWHCLEE
                     NEAMQDVDDFELRALVAENMDLPAIPPRYRSSYFAHIFGGGYAAGYYAYLWTQMLADD
                     GYQWFVEQGGLTRENGLRFREAILSRGNSEDLERLYRQWRGKAPQIMPMLQHRGLNV"
     gene            29024..29770
                     /gene="ydfG"
                     /locus_tag="IRB70_002851"
     CDS             29024..29770
                     /gene="ydfG"
                     /locus_tag="IRB70_002851"
                     /EC_number="1.1.1.298"
                     /EC_number="1.1.1.381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional NADP-dependent 3-hydroxy acid
                     dehydrogenase/3-hydroxypropionate dehydrogenase YdfG"
                     /protein_id="HBC0632741.1"
                     /translation="MIVLVTGATAGFGECITRRFIQQGHKVIATGRRQERLQELKDEL
                     GDNLYIAQLDVRNRAAIEEMLASLPAEWCNIDILVNNAGLALGMEPAHKASVEDWETM
                     IDTNNKGLVYMTRAVLPGMVERNHGHIINIGSTAGSWPYAGGNVYGATKAFVRQFSLN
                     LRTDLHGTAVRVTDIEPGLVGGTEFSNVRFKGDDGKAEKTYQNTVALTPEDVSEAVWW
                     VSTLPAHVNINTLEMMPVTQSYAGLNVHRQ"
     gene            29859..30545
                     /gene="ydfH"
                     /locus_tag="IRB70_002852"
     CDS             29859..30545
                     /gene="ydfH"
                     /locus_tag="IRB70_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YdfH"
                     /protein_id="HBC0632742.1"
                     /translation="MTVETQLNPTQPVNQQIYRILRRDIVHCLIAPGTPLSEKEVSVR
                     FNVSRQPVREAFIKLAENGLIQIRPQRGSYVNKISMAQVRNGSFIRQAIECAVARRAA
                     SMITESQCYQLEQNLHQQRIAIERKQLDDFFELDDNFHQLLTQIADCQLAWETIENLK
                     ATVDRVRYMSFDHVSPPEMLLRQHLEIFSALQKRDGDAVERAMTQHLQEISESVRQIR
                     QENSDWFSEE"
     gene            30722..30925
                     /gene="ydfZ"
                     /locus_tag="IRB70_002853"
     CDS             30722..30925
                     /gene="ydfZ"
                     /locus_tag="IRB70_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenium delivery protein YdfZ"
                     /protein_id="HBC0632743.1"
                     /translation="MTTYDRNRNAITTGSRVMVSGTGHTGKILSIDTEGLTAEQIRRG
                     KTVVVEGCEEKLAPLDLIRLGMN"
     gene            complement(30961..32421)
                     /locus_tag="IRB70_002854"
     CDS             complement(30961..32421)
                     /locus_tag="IRB70_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBC0632744.1"
                     /translation="MGNNLLSAKATLPVYDRNNLAPRIVHLGFGAFHRAHQGVYADIL
                     ATEHFSDWGYYEVNLIGGEQQIADLQQQDNLYTVAEMSADAWTARVVGVVKKALHVQI
                     DGLETVLAAMCEPQIAIVSLTITEKGYFHSPATGQLMPDHPMVVADVQNPHQPKTAIG
                     VIVEALARRKAAGLPAFTVMSCDNMPENGHVMRDVVTSYAQAVDVKLAQWIEENVTFP
                     STMVDRIVPAVTEDTLAKIEQLTGVRDPAGVACEPFRQWVIEDNFVAGRPEWEKAGAE
                     LVSDVLPYEEMKLRMLNGSHSFLAYLGYLAGYQHINDCMEDEHYRHAAYALMLHEQAP
                     TLKVQGVDLQDYANRLIERYSNPALRHRTWQIAMDGSQKLPQRMLDSVRWHLAHDSKF
                     DLLALGVAGWMRYVGGVDEQGNPIEISDPLLPVIQKAVQSSAEGKARVQSLLAIKAIF
                     GDDLPDNSLFTAKVTEAYLSLLAHGAKATVAKYSVK"
     gene            complement(32511..33794)
                     /gene="ydfJ"
                     /locus_tag="IRB70_002855"
                     /pseudo
     CDS             complement(32511..33794)
                     /gene="ydfJ"
                     /locus_tag="IRB70_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000582800.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter YdfJ"
     gene            34399..34512
                     /locus_tag="IRB70_002856"
     CDS             34399..34512
                     /locus_tag="IRB70_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632745.1"
                     /translation="MNSILIITSLLIIFSIFSHALIKLGIGISNNPDKTDV"
     gene            34581..>34738
                     /gene="ydfK"
                     /locus_tag="IRB70_002857"
     CDS             34581..>34738
                     /gene="ydfK"
                     /locus_tag="IRB70_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416062.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein YdfK"
                     /protein_id="HBC0632746.1"
                     /translation="MKSKDTLKWFPAQLPEVRIILGDAVVEVAKQGRPINTRTLLDYI
                     EGNIKKKS"
BASE COUNT         8992 a         8721 c         8200 g         8825 t
ORIGIN      
        1 tctgcaagct ggcatttaac aagccagttc taaaagaagg gaaataagaa taactatact
       61 caaaaactaa cagccacggt catcatgatg tggctgtcaa tgaaactata acccaggcgc
      121 tttccataac gacgtcgtca gtccatgatc aaccagcccc agctgatcct gataaactgc
      181 ctgccactta tcgcgtgaat cctgataaag ttcatgcttt tctgggtctg gtgtgtgcgt
      241 ccgttcccag cgaaccaggc gttctccggt ttctgccatt gatgaaaaaa ttccggcacc
      301 gacgccagct gcaatggcac atcctaatgc agtggcttct ttgaccaccg gaatattgac
      361 gggtaatccc gagacatcag cgagaatttg actccataat ttcccttttg aacctccgcc
      421 tgcaaagact agagatgtgg gatgaatatt cgaaaaatca gcaatttgct gcaagttaca
      481 cgctgataca atcgccgcat tttcttccag cgcacggaac aatgtcgctt tgttacattt
      541 atccgggtca atggacaagt taataaagga aggcgcagcg tgataccagg ttttaaagcg
      601 cattctgtcg gagaatatcg gcattacgcc ccacgaccca ggcggcacac gacttgccat
      661 ctcttcaagc agcgtatagg tgtcgatgcc taaacgttcg gcaatcagtt tttcttcggc
      721 acagaaagca tcgcggaacc agcgcatggt gagtccggta aaaaagctta tagattcagc
      781 ttgtaccatg ccaggaataa catggggatt aacgcgcacg ttcatttctg ggtctgtcac
      841 cggcgcggct aagtttacaa cttgctgcca gaatgtaccg ccaagaaccg cggtttgtgc
      901 cggacggaca acgcctaacc ccaggcaacc aagctgcacg tcacctcctc caacgaccac
      961 cggagtgccc gccttcagac cgcagagttc cgccgcttgt gaacttacca cgcccagcaa
     1021 tgtgccggtt tctttgacag gagaaagaat atcggcccgc agtccggcca tatccagcaa
     1081 tgcaggtttc cagtcacggg tggttagatc aagaagtccc gtggtgccag cgttagaggg
     1141 atccaccgcc agttcgccgc tgagcatata ggccagccag tcgctgatca tggtgatggt
     1201 cgacgcctgt cggtagatat cggaacgatg gtgcgccagc caaagtaatc tggggatggc
     1261 gcttaaagcc agcgtttgcc cggtcgctcg ataaactttg ttttcaaagg tattgttgtg
     1321 cagttcttta agttcgctaa cttcgcgcgc cgctctggca tccacattgg cgcaggccca
     1381 gatcggtgtt ccatcattgt tatataaaac aatgccttca cgcatcgaac atgccgaaac
     1441 ggcagcgata tactccgggg ctatgccggc gttgtgcagc gcctggcgca tacactcaca
     1501 cgccagttgc cagtttttgt tgagatcaaa ttccatagaa ccaggaacgt ccggtactgc
     1561 caggtgccgc cactccgcct gtctcacggc tatttgattg ccttccaggt cgaatatcac
     1621 agcccgaata cttccggtac ctgcatccag cgccatcagg taatactttg attctgaagg
     1681 ggtaaagagt cgagccatta gattatcctc ggcttatgcg ttctgtctgt tcctctatac
     1741 gttctccatc attcccggta ataaggtcat gcaaatttaa ctacgtaaaa tcgccgctgc
     1801 tgtatcctga tcggtaacca gtgcgttgat ataaccgcct ttcattgcag cggcaattgc
     1861 ttcggcttta ttttctcccc ctgccacgcc aacccggacg ggtatggtct tcagcgcgct
     1921 taaaggtaag ccaatcagtt cgttatgtat tttaatatcc gtgacaacgt caccttttgc
     1981 atcaaaaaag tagcctaaaa tgtcgccaac cgcccctttt cgaccaatca ttaactgttc
     2041 gccctggctg atatagccgg agcgaatgat tgttgcgtcg tcttgttgac tcacagcccc
     2101 aatgccgaca atcgccacat ccgctgcttg cgcggctagc agaacatctt tgacgcaatt
     2161 ttcatttttt aacgtacggg caatgtcagc ggaggatgcc cgcaacggag ccggaataat
     2221 attcacactg cacgccgcgt taagctgccc gatacccgtc atataagaac cgactccacc
     2281 ggagagcgtg accaggcgaa tttgctgtga cgaaataaaa ccacttaagc gttgcagcgt
     2341 attcatggtt gcctcgccaa aaccaatcgc cagcatctgt tgtggttgaa gtaaactcat
     2401 caacatatgc gccgcgccta tccctagtcg cccgccgaca tcagcatccg caagccctgg
     2461 gatcacccgg acatgttgca gcgaaaactg acgacgtaat tgtgtttcat attccagaca
     2521 gccttcaaag cgagaattaa tctgtacgcg aataatgccg gattgatgcc ctttctccag
     2581 taatcgcgac actttcaaac gggtcaggcc gagacgatcg ctgatctcac tctgggtcag
     2641 cccgtcatgg tagtaaaacc acgcaatccg cgcgacctgt tcttcttcac acattccctg
     2701 ttctgaaatt accgaatcgt tgattgtcat aattcattct tcactttgaa catacttaaa
     2761 tctttaatgc aattgttcag ttcttgcgca tttatatctg tgatggcaac cacagtttga
     2821 ctctatgagt atgaacaaac gcaaccgtga aaatcaaaat agcataaatt gtgatctatt
     2881 cgtcggaaat atgtgcaatg tccacctaag gttatgaaca aattaaaagc agaaatacat
     2941 ttgttcaaaa ctcacctgca aaactgaacg ggggaaatat gcaaacgagt gatacccgcg
     3001 cgttaccgct actttgcgcc cgctcggttt ataaacagta ttcaggagtt aatgtcctga
     3061 aaggcatcga ttttacgttg catcaggggg aggtccacgc cctgctcggc ggcaatggtg
     3121 ccggtaaatc gacgttaatg aagattattg ccggtattac ccctgctgat agcggtacgc
     3181 tggagattgg gggcaacaac tacgtcagat taacgccagt tcatgctcat cagctgggca
     3241 tttatctcgt tccccaggaa ccgctgcttt ttccaagcct gtcgataaaa gaaaacatcc
     3301 tgtttggtct ggcaaaaaaa caactctcca tacagaaaat gaataacttg ctggcggcgc
     3361 tgggctgcca gtttgatctg catagtctgg caggatcgct ggatgtcgcc gatcgccaaa
     3421 tggtggaaat cctccgcggg ctgatgcgcg attcgcgaat tctgatcctc gatgaaccta
     3481 ccgcctcgct tactcccgcc gaaaccgaac gtttgtttat tcgcttgcgg gagttgcttg
     3541 ctactggcgt gggtattgtt tttatctcgc ataagctgcc ggaaattcgc cagattgccg
     3601 accgaattag cgtgatgcgc gacggaacca tcgccttaag cggcaaaacc agcgaactgt
     3661 ctaccgacga cattattcag gccattacgc cagcgctacg ggaaaaatcg ctctctgcca
     3721 gccaaaaatt atggctggaa ttacctggca accgcccaca acatgccgcg ggaacgccgg
     3781 tgctgacact ggaaaatctg accggcgaag gtttcaggaa tgtcagcctg acgctcaatg
     3841 ccggagaaat tctgggcctg gctgggctgg tgggagccgg acgcacagaa ctggccgaga
     3901 cgctctatgg tctgcgtact ttgcgtggcg gacgcattat gctgaatggt aaagagatca
     3961 atagattatc caccggagaa cgtttactgc gcggtctggt ttatctgccg gaagatcgcc
     4021 agtcatccgg acttaatctc gatgcttcac tggcgtggaa cgtctgcgcc cttactcata
     4081 accttcgtgg attctgggcg aaaaccgcga aagataacgc cacactggaa cgttatcgtc
     4141 gggcgctgaa tattaaattt aaccaaccgg aacaagctgc gcggacctta tccggcggca
     4201 accagcaaaa aatcctgatt gccaaatgtc tggaagcttc gccgcaagtt ttgattgtcg
     4261 atgagccgac gcgcggcgtg gatgtctcgg cgcgtaatga tatctaccaa ctgttgcgca
     4321 gcatcgccgc acaaaatgtg gctgtgctgc ttatctcctc tgatctggaa gagatcgaac
     4381 tgatggcaga tcgcgtgtat gtgatgcatc agggcgaaat tgcccactct gcactgaccg
     4441 gacgcgatat taatgtcgag accattatgc gcgttgcctt cggagatagt cagcgtcagg
     4501 aggcgtcatg ctgaaattta ttcagaacaa ccgtgaaatc acggcactgc tggcggtggt
     4561 gctgctgttt gtattacccg gttttctcga ccgtcagtat ttaagtgtgc aaacgctgac
     4621 catggtttat agcagcgcgc aaatcctgat cctgctggca atgggcgcga cgctggtaat
     4681 gcttacgcgc aatattgatg tttcagtggg ttcgattacc ggaatgtgcg cggtgctgtt
     4741 ggggatgtta ctgaacgcgg ggtattcact acctgttgct tgtgtcgcga ctttactgct
     4801 tggtttgctc gcgggatttt tcaacggtgt cctggtcgcg tggctaaaga tccctgccat
     4861 tgttgccacc cttggcacgt tagggttgta cagaggcatc atgttgctgt ggactggcgg
     4921 taaatggatt gagggattac ccaccgaact gaaacaactc tccgccccgc tgctgtttgg
     4981 cgtttccgcg attggttggt tgacgataat tctggtggca tttatggcct ggctgctggc
     5041 aaagacggcg tttggacgca gtttttatgt cacgggcgat aatttacagg gcgctcgtca
     5101 actgggcgtt cgtacggaag ccattcgcat tgtggcattt tcgttgaacg gctgcatggc
     5161 ggcactggcg ggaattgtgt ttgcttcgca gattggtttt atccccaacc agaccggtac
     5221 cgggctggag atgaaagcaa ttgcagcctg cgtgctgggc ggcattagtt tgctcggcgg
     5281 ttccggcgcg atcatcggtg cggtactcgg cgcatggttc ctgacgcaga tcgatagtgt
     5341 actggtgctg ttgcgcattc cggcatggtg gaatgatttt atcgcgggca tggttctgct
     5401 ggcggtgctg gtgtttgatg gacgcctgcg ttgtgcgctg gaacgtaatc tgcggcggca
     5461 aaaatatgcc cgctttatga tgccaccgcc atccgttaaa cccgcttcgt caggtaaaaa
     5521 acgggaggcc gcgtaatgcg tattcgctac ggttgggaac tggctcttgc cgcactgctc
     5581 gttattgaga ttgttgcatt tggtgcaatt aacccgcgga tgttagatct caatatgttg
     5641 ctgttcagca ccagtgactt tatctgcatt ggcattgtcg ccctaccgct gacgatggtg
     5701 attgtcagtg gtgggatcga tatttcgttt ggttcgacca tcggcctctg cgccattgca
     5761 ttgggcgtac tgtttcaaag tggtgtgccg atgccgctgg cgattcttct gaccttactg
     5821 ctcggcgcat tgtgcgggtt gatcaacgcc ggattaatta tctataccaa agttaacccg
     5881 ctggtgatta cgcttggcac gctgtatctg tttgccggaa gcgccctgct gctttccggg
     5941 atggccggag cgacggggta cgaaggtatt ggtggattcc cgatggcgtt tacagatttc
     6001 gctaacctgg atgtgctggg actccccgtt ccgctgatta tcttcctgat atgtctcctc
     6061 gttttctggc tctggctgca taaaacccat gccggacgta acgtgttttt aattgggcaa
     6121 agcccgcgtg tggcggttta tagcgcgatt ccagttaacc gcaccttgtg tgcgctctat
     6181 gccatgacgg ggctggcgtc tgcggtcgcc gctgtgctgc tggtatcgta ttttggttca
     6241 gcacgttccg atctcggtgc gtcgtttctg atgcccgcca tcaccgccgt agtgctcggc
     6301 ggtgccaata tttatggtgg ttctggttcc attatcggca ccgccatagc ggttttatta
     6361 gtgggatatt tgcaacaagg tttgcaaatg gcaggagtgc caaatcaggt gtccagcgcc
     6421 ctttccggtg cgctacttat cgtcgttgtc gtaggtcgtt ccgttagcct gcatcgccag
     6481 caaattaaag agtggctggc gcgtcgggcc aataacccat tgccataaag gatatcttca
     6541 tgacacttca tcgctttaag aaaatcgcct tacttagcgc gcttggcatt gccgtaatct
     6601 ctatgaatgt gcaggcggca gagcgtattg catttattcc caaactggtt ggcgtgggat
     6661 tttttaccag cggtggcaac ggcgcacaac aagcgggtaa agagctgggc gttgatgtga
     6721 cctacgacgg gccgacagaa cccagtgttt ctggtcaggt acagttgatt aataacttcg
     6781 tcaatcaggg ttataacgcc attatcgttt ctgcggtttc gcctgatggc ttgtgtccgg
     6841 cactgaaacg cgccatgcaa cgtggtgtga gagtgctgac ctgggactct gatactaaac
     6901 cggagtgccg ctcttactac attaatcagg gaacgcccgc ccagttggga ggtatgttgg
     6961 tggatatggc ggcgcgtcag gtgaataaag acaaagccaa agtcgcgttt ttctactcaa
     7021 gccccaccgt tacggaccaa aaccagtggg tgaaagaagc gaaagcgaaa atcgccaaag
     7081 agcatccagg ctgggaaatt gtcactacgc agtttggcta taacgatgcc actaaatcgt
     7141 tacaaaccgc agaaggaata ttaaaagcct atagcgatct cgacgccatt atcgcccccg
     7201 atgccaatgc cctgcccgct gccgcacaag ccgcagaaaa cctgaaaaat gacaaagttg
     7261 cgattgtcgg attcagtacg ccaaacgtga tgcgtccata tgtggaacgc ggcacggtga
     7321 aagaatttgg cctgtgggat gtggttcagc aaggcaaaat ttcagtttat gtcgcggatg
     7381 cattattgaa aaaaggatca atgaaaacgg gcgacaagct ggatatccag ggcgtaggtc
     7441 aggtggaagt ctcgccaaac agcgttcagg gctatgacta cgaagcggat ggtaatggca
     7501 tcgtactgtt accggagcgc gtgatattca acaaagagaa tatcggcaaa tacgatttct
     7561 gatgtgcatt acttaaccgg agtacgttat ggcagattta gacgatatta aagatggtaa
     7621 agattttcgt accgatcaac cgcaacaaaa tatccctttt atcctgaaag gttgcggtgc
     7681 actggattgg ggaatgcagt cacgcttatc gcggatattt gatccgaaaa cgggtaaaac
     7741 cgtgatgctg gcctttgatc atggttattt tcaggggccg actaccggac ttgaacgcat
     7801 tgatataaat atcgccccgc tgtttgaaca tgcagatgta ttaatgtgta cgcgcggcat
     7861 tttgcgcagc gtagttcccc cggcgaccaa taagccggtg gtactgcggg cgtcaggtgc
     7921 gaactctatt ctggcggaat taagtaatga agccgtggcg ttatcgatgg atgacgccgt
     7981 gcgcctgaac agttgcgcgg tggcggcgca ggtttatatc ggcagcgaat atgaacatca
     8041 gtcgatcaaa aatattattc agctggtcga tgccggaatg aaagtgggaa tgccgaccat
     8101 ggccgtgaca ggcgtgggca aagatatggt gcgcgatcaa cgttatttct cgctcgcgac
     8161 tcgaatcgcc gctgaaatgg gggcgcagat tatcaaaact tattatgtcg ataaaggttt
     8221 tgaacggatt gttgccggat gtccggtacc cattgttatt gctggcggta aaaagttacc
     8281 ggagcgcgag gcgctggaaa tgtgctggca ggctatcgat cagggcgctt ctggtgtgga
     8341 tatgggacgt aatattttcc agtctgacca tccggtggcg atgatgaaag ccgtacaggc
     8401 ggtggtacac cataacgaaa cggctgatcg ggcatatgaa ctctatctga gtgaaaaaca
     8461 gtaactgcgg atttaaggag aagaattatg cacgtcacac tggttgaaat taacgttcat
     8521 gaagacaagg ttgacgagtt tatcgaagtt tttcgccaga accacctggg ctcggtacag
     8581 gaagaaggca atttgcgctt cgatgtctta caggacccgg aagtgaattc gcgcttttat
     8641 atctacgaag cttataaaga tgaagacgca gtggcgttcc ataaaaccac gccccactac
     8701 aaaacctgtg tcgcaaaact ggaagcttta atgaccgggc cgcgtaaaaa acgtctgttc
     8761 aatggattga tgccgtgagg cgaatttatc agttttatct acactagggg taacgcgctg
     8821 acgggagtaa aaatatgtct gactggaacc cctctttata tctgcacttt gccgctgaac
     8881 gatcgcgtcc ggcgatggag ctgcttgcca gagtgccgct ggagaatatc gaatacgttg
     8941 ccgatcttgg ctgtggccca ggtaacagca ccgcactgct gcatcaacgt tggcctgctg
     9001 ccagaataac gggcatcgac tcgtctccgg cgatgattgc tgaagcgcgc agtgctttgc
     9061 cagactgcca gttcgtggaa gcagacatcc gcaactggca accggaacag gcactcgatc
     9121 tgatttttgc taatgcctca ctgcaatggc tgcccgccca ctacgaattg ttccctcatc
     9181 tggtttcttt acttaattcg catggtgtgt tggcagtaca gatgccagat aactggctag
     9241 agccaaccca tgtgctcatg cgcgaagtcg cctgggaaca aaattatccg gatcgcgggc
     9301 gtgagccgct ggctggcgtt catgcttact acgatatttt gagcgaagcc ggatgtgagg
     9361 tcgatatctg gcgaaccact tactatcacc agatgccgtc gcaccaggcg attatcgatt
     9421 gggtgaccgc cactggatta cgtccgtggt tacaggatct gaccgagagc gaacagcagc
     9481 attttcttac gcgctaccat cagatgctgg aagagcagta tccactgcaa gagaacggag
     9541 agatactgct ggcatttccg cgtctgttta ttgttgcccg gcgtacggag taaatattac
     9601 gtcagctggt aatgacgatc gggaagaatt tttgctggaa tttctgcttc atcgttcatc
     9661 tgtaacaggt caatttcaat agcgttgcag atggcatcca gcggtaaatc attgttttca
     9721 ataccgaagg gatcttccag ttcttccgcc agacaatcca gcgaaataaa agtgtaggaa
     9781 atcagcacag agataaaagg cgtcatgtaa tgcagatcca cgaccagcgc gaacggcagc
     9841 atgatacaaa acagataaac ggtacgatgc aaaatcaggg tgtaggcaaa gggaattggc
     9901 gtataggcaa tgcgctcgca gcctgccaga accgctgaaa tatcgttaag ccgatcgttg
     9961 aggctaataa acaggatatc tgaaagctgc ccattgcggc gctgaaccgc caaccactcc
    10021 cccattatta acaagatacg gttagctgga gagttcgaag tcagtacacg ctgaagatct
    10081 tccgtcttga gatattgagc cagcacttcc gcctgtggtt gtttgcgtaa tgtcatgcgt
    10141 aaacagtgag cgaaggcgat ttgcagccgg gcaaactccc ttacacttgc cgaatccggc
    10201 aatgtcgttt ttacctcgcg cagtaacgac cgtgaggcaa tcatcaactg cccccaaagt
    10261 tttcgcgctt caacgtaacg ggcgtaaccg gcattattac gaaaaccaag aaaaatggcg
    10321 atggcgacac cgagaatgct gaacggtgcg agggtgaatt tgatgcccag atgcgtgtac
    10381 cagggcagca tgaaaataac agcgatagaa aagagaaaat tgagtagtaa acgcgaggat
    10441 atcttggata atactgagcc gtgccagaca aaaatacggc gcagccagtg ttgttgtgga
    10501 cgaacaatca tggttatctt caggcgtgga aaagtcgccc tattaaacgt gattacgatc
    10561 acattctcaa gacactactt acaaattacc tacaagctta caacattaac aggtgctgca
    10621 tgtagcacct gttaatgata aaggcacata ggatgttgta actaatatag tgaaataaga
    10681 aacccggtcg aaaccgggtt cagagtatta gcacaacgga cgtacagctt cgcgcattcc
    10741 tttttcgaga atcgcatcca ggtcattagc aacctgctcg accagaccag gcacttgcgt
    10801 caggtcctgc tcccagtggt ctttttctgc caaaacaatc gctaccagtt cctgggtgcc
    10861 gataacacgg ttacgatgct ggctccagag ttgctgataa cgttccagcc agtgggcatc
    10921 gtcctgtacc ggatatgttt ctccattacg ctcaccgcga tagaacgcaa tcaatgctgc
    10981 taatgcgaaa gtaaggcgcg ccggaagtgt gccgtttgcc ttctgccctg ccagcagctg
    11041 cggcaggata cgggtgcgga acttggtcat accgttgagc gcgatagaca gcagctgatg
    11101 cttaatgtac gggttacgga aacgcccggt gacagcactg gcgaaagatt ccagttcatc
    11161 acgaggcaaa tccagtaccg gaataatctc ttcgtagatg gctttttcaa cgaatgcgca
    11221 aatttcagca tcgttcatcg cttcacctac ggtatccagc cctgcctgga acgccaccgg
    11281 caccagcgcg gtgtgcgcac cgttgaggat tgccactttg cgctctttat acggtttaat
    11341 atcgtcaaca atcagcacgt tgagcggata tttgtccaga cgcagctcag tcgctaagga
    11401 tttcggcccc tgaatcacaa acaggtaaaa gtgttcagcg gtgtcgagga aaccatcgtg
    11461 ataacccagt tcttcttcca gtttagccac ttcatcacgc ggatagccgg taacgatacg
    11521 gtccaccagc gtagaacaga agctgttagc ctgatccagc cattgaataa atgcttctgg
    11581 cagtgcccac tcttgcgcgt agcgcagcac cagttcacgc agtgcatcgc cgttatagtc
    11641 gatcagttca catggtatga tgatccaacc tttatcctgc gctccgttga aatggctaaa
    11701 acgttcgaac agcagacggg tcagttttgc cggataactt accgctggcg cgtcatcgaa
    11761 tttatcgccc gcatggtagc tgatacccgc ttcggtggtg ttagagaaaa caaagcgcat
    11821 ttccgggttg tgcgccagtt tcaggaattc atcgtattca ctgtagacgc tgatttcacg
    11881 attaacagag cgaatcagac gcgcgtcgct gaccgcttcc cccttctcgt tcagaccacg
    11941 gataatggtg gtgtacagac catcctgcgt gctcagtgac ggcgggaatg aagtttcaat
    12001 cggacgaaca acgaccacgc cagaattcag atcggtgtgc tcattcagga gatcgatttg
    12061 ccagtcaaca aaggcgcgca ggaagttacc ttcaccaaac tgaatgatac gttctggata
    12121 ctgtgcaccg ggaaaatcgc gacgatttag tgttttcaca atgggttccc ttctgattag
    12181 tcatacaacc tgtttgaatt ggtacgacag gttagcaaac tttaatacgc cgaacccctg
    12241 ttttgatcaa ctcctgatga ttaatgagca gttttatgag aaaagtgtgg cgcggatcat
    12301 ggtttaatcg aggaactacg ccttttattc gctcaataaa gtggtagaac acattccatt
    12361 taaatcgctg tgaatgaata aagatgtcag acaacttcct caccgtaacg catagtgctg
    12421 gtacggttgc gcccatcttt cttcgagcga tacagacatg tatcggcttc gaccatcaat
    12481 ttattaaagt catcggtcag cgttcggtac gatgcgcaac cactaccgac gccaatactt
    12541 accgtgagat aaagcgtttt ttgttgccag gtgaacggtt gcagttcaac gcctttacgg
    12601 attttttccg ccattagcag accatcgaca ggattcaccg atggcactgc aacagcaaat
    12661 tcctcgccgc ccattcgcgc caccagcccc ttatcaccga caatcttctg aatatgctgg
    12721 gcaaacacgc ttaacacttt atcgccacat tcatgtccat agttatcgtt aatgcttttg
    12781 aaatagtcga tatcaagcag catgacagtc agatgttgtg tctgtttcag cgatggactt
    12841 ttcagcgcct cataaagacc ggaccgtgag taaacctgag tcagaaaatc aaagtcggct
    12901 cgcagcgcaa cttgcttcat tagcgaattg atcgctgcca cgctaaaaga aaccataatt
    12961 gggcatatcg ccatcgtggc aataccgaga cgtgcggaga acatttctgg aatggagaat
    13021 ggcgaaccga ccgagatatc aatcaccgaa tttgccacca gtacgatttc caccgcaccg
    13081 gtgacaaagg tcaacagaca tgttacctgc ggcgtatagc gcactgcaca ccagattaat
    13141 gcaggcagcg ggaacgccag actccccgct ccgccaatga ctaccgaggc aataaccgac
    13201 acaataagcg cgatggcggg catcatctgt tctgctttaa agcgcggcag cactcccgga
    13261 atagccaacg tcagcataca aggcacgatc aacacgcccg ttgagaattg ctcactgaac
    13321 cagtccgcaa gcaaaggcca gaaatccaga ctatcaatac tgaccgaacc aatcgccccg
    13381 acaatagcgc ataataatgc ggcaatcaga cagtaattaa atagccgtaa ggcacttact
    13441 ggctcatact tatttttccc caaacgctta tcccgcacga ccagtaaggc gacggtaaca
    13501 ataaacatca tattggagaa attgatagcc agtgaaacca gcccccattc ggtggttatg
    13561 gcatcataaa ccagcatcgc cacataactg atcgcatagt aatgcagtcg attaagccag
    13621 acatagcggg caaacacccc cgccattacg ccattcagcg gccagaaaag agaaagttcg
    13681 tgaaccagcc gtaactctgc accaatgaaa tagaacagcg tggttagcgc aaaaatagcg
    13741 atgctattac gtagcagatg accttcctgg aacaaacgga aagttgaaat ggggtgtaca
    13801 tgcattaatt atctgtccat acaattgcgg gtggcaatta tctcaacgta ataagtaaat
    13861 tcttataaag gatagcatgt tcgctgacag cggcggcaaa taaagatacc taatgaatgc
    13921 cattttatcg atttccgtaa ttatcatggc tgattcatct gtataaccag ccagtgatag
    13981 attaccgtca caatataacg ttgttgctcc tcacttaacg cttccccttg aggaatgtta
    14041 tgccacttag ccagacaacc gcgacaacag gtcgcggtgg cgtgttgagc gataaaaacc
    14101 ggatgcccgc gcatgggggt ttgcttaccg tcgttagccg gtaatgccgg agcaagacgt
    14161 ttagcgacaa aatccgccgc atgttgttcg atgactggcg cacctttctc cagacaatac
    14221 tgacgctctt tcatgcccaa acgaaagcga gagcgaaatt ttgaacggga taaacgcgcg
    14281 aagagtggat cgagagactg cattaataaa ctgaacgccc taattgtttc gtcaattgtt
    14341 caaggacagc aatgcccgca agcgagttac cggcatcatc cagttccggg ctccagactg
    14401 cgatggccat ttcatgcgga acaatcgcca caataccgcc accaacgcca gattttgccg
    14461 gtagtcccac ccgccaggca aactcccccg cgttctggta cataccactg gtcgccatca
    14521 gcgcgttaat ttgccgcgcc tgcattggcg tcaccacagg ttcatcaata tgaatagctt
    14581 taccctgatt agccagaaag acaaacgtcc gggccagctc tacacagctc attttcagag
    14641 cgcagtaatg aaagtagttt tgcagaacgg ttgtcacatc atgatggaaa ttgccaaacg
    14701 acttcatcag ccaggcgata gccgcatttc gcgcggagtg ttcaaattcg gaacgcgcta
    14761 ccaccgtatc gtaggaaata tcagacacac cgcttaagcc gcgcacgact tccagcatac
    14821 gttgccgagg agcgcttaat cgcccttgca acatatcgca gaccaccagc gcaccggcat
    14881 taataaacgg attacgcgga ataccctgct ccatttccag ttgcactaaa gaattgaacg
    14941 gtgatccaga cggatctttg ccgacgcgtt gccagatttc ctcttcggag taatgacgca
    15001 tggcgacaac gagactcagc actttggaaa tagactgaat ggaaaaacgt tcttgcgcgt
    15061 ctccggcctg aaaaagctgt ccgtcaacgg tacagatagc aatccccaat cgggaaccgt
    15121 ctaccgtagc cagcgccgga atataatccg cgactttacc ctgaccaatg agcggccgca
    15181 cttgccgcaa gatgttttct aaaattgcat tatccatggc gactgccact ttctactcct
    15241 ggaccgcagg tctgaaaaga cctgcgagta tatcagagct gaatatatag cgtcagaccc
    15301 ggtctttcca caccgtctgg atattacaga attcgtgtaa gccaaaatgg gaaagctcac
    15361 gcccaaagcc actcttcttc acaccaccaa aggcgactcg cgcgtcgctg gcacagtaac
    15421 cattgataaa caccccaccg cattccagac gtgccgccat ctgtctggcc cgggtttcgt
    15481 cggtggtgaa aatggtcgct gaaaggccga actcgctatt attagccagt tccagtgcat
    15541 gttctgcatc tttcgcaatg gtgattgccg caacggggcc aaacatttct tcccgaaacg
    15601 cggtcatttc tggggtaaca ttcgccagaa ccgttggcgg atagtagtta cctgccccag
    15661 ccatcttttc cccgcccagt aacaaacgcg caccctgcgc cagggttttc tccacctgat
    15721 gatgcagctc atcacgtaaa tcaaaacgag ccattggtcc gagagtgttc tcttcgtcac
    15781 ggggatcgcc cattttcaag gctgccgcag ctgccacaaa acgttcggta aatgccgaag
    15841 caattccctc ttcgatgata aagcgttttg ccgctgcaca aacctgtccg gtattctgat
    15901 aacgtccggc taccgccgct ttaaccgcca gttccagatc ggcatcgtta agcacaataa
    15961 atggatccga accgcccagt tccagtacgc attttttcag tgccgctcca gcctgtgcgc
    16021 caatagccgc tcccgcacga acacttccgg tcaccgtgac agcagcaatg cgcgagtctt
    16081 taatcatctg actgacgccg tcgttgtcgg cattcagcca gccatatacg ccttgtggga
    16141 tacccgcatc tttaaacacc tgggcaatga gctgtgcaca gcccatcaca ttcggcgcat
    16201 gtttaagtaa gtagccgtta cctgcaagaa tgatgggaac cgcgccacgc atcacctgcc
    16261 ataacggaaa attccacggc ataatcgcca gaattgtccc caacggtcga tactcaataa
    16321 ctgcctgctg attttccacc agcgtaggtt ccgccttcag cattgccgga ccatgttctg
    16381 cataccagtc acacaaattc gccgatttcg ccacttcagc gcgcgcctgg ttgattggtt
    16441 tgcccatttc acgggtgatc atttgcgcca tttcttcgct acggacacgc agagccttac
    16501 cgatatcacg cagtttttca gcacgataat ctatatttgt ctcgcgccag tcgcgaaagc
    16561 ctgctgccgc cagctgaagt gcgttttcga tatcatcagc gccagcccac ggcagcacag
    16621 aaagttgttc accggtggca ggatttatcg aaattgcatg agttgccgga gtaatggtca
    16681 tcggggtatc tcctttatgg gttatggtaa aaagatacgc agatttactc ttgcttgaaa
    16741 atgaataata ttaagccact tattcacgaa tcgagaatat tatggatctg acccaactgg
    16801 agatgttcaa cgcggttgcc gaagctggca gcattaccca ggctgcagca aaagtgcatc
    16861 gcgtgccgtc gaatctcact acccgtctac gccagctgga aacagaactg ggggttgatc
    16921 tgtttattcg cgagaatcag cgtttacgtc tctcgcctgc cgggcataac tttttacgct
    16981 atagccaaca aattctcgcg ttagtggatg aagcgcggag cgttgtcgct ggcgatgagc
    17041 cgcaaggttt attttctctt ggttcgctgg aaagcaccgc tgcagtgcgc attccggcca
    17101 cgctggcgga atttaaccgt cgttatccca aaattcagtt ttcactttcc accggccctt
    17161 ccggcactat gctggaaggt gtgctggagg gaaaactgaa tgcagcgttt attgatgggc
    17221 ccattaacca tactgccatt gacgggatac cggtgtaccg cgaggagctg atgatcgtca
    17281 cgccacaagg acatgcgcca gtaacccgcg ccagtcaggt aaatggcagt aacatttatg
    17341 ccttccgcgc caattgttcg tatcgtcgcc acttcgagag ctggtttcat gctgatggtg
    17401 ccgctccggg aactattcac gagatggagt cgtatcacgg gatgttggcc tgtgtggtcg
    17461 caggagcagg cattgcgctt attccacgct ctatgctgga aagtatgccg gggcatcacc
    17521 aggttgaagc gtggccgtta gctgagcaat ggcgttggtt aacaacctgg ctggtctggc
    17581 gtcgcggtgc gaaaacgcgt ccgcttgagg catttattca actactggat gcgcctgact
    17641 cggcaaaaca gggttaccaa tgagctattt ttgatagttc ttgcggctaa tatgctctat
    17701 atagtgatgt tccgatgact tatgactata tggggcaaat atggttacgc cagtaagcat
    17761 cagcaattac atatctcttc ctgatgattt tcccgtacgt aatattgcac cgcaggtaaa
    17821 agaagtttta aaggatttca ttgatgcact tagtacaata atatgtgatg aagaatggcg
    17881 cacgtcttta aacatcaact cagccacaaa aaagatattt aataaccttg acaacttatc
    17941 atatattcag aggacttctt ttcggggtaa cgacacgcta tacaatgaaa aggttcagtt
    18001 taaactcact tatcccgtca agaatggaag acacaaagaa aatattgaat ttcaggtagt
    18061 aataaattta agccctattt atttagataa tttccgccat gatggggaaa ttaatatttt
    18121 ttgcgctccc aacccaaagc ctgtcactat ggggcgcgta tttcagaccg gcgtcgagcg
    18181 tgtactcttt ctgtttctga atgactttat agaacaattt ccaataatca accctggcgt
    18241 tcctatcaaa agagcgcata cgccacatat tgaacccctg catccggatc accataccgc
    18301 tgcagattac atacgccagt ttgatttgct tgtcctgaat tttatctctc gcggtaattt
    18361 tgtcatactc ccccgattat ggaataactc tgaggttcac agatggttcg ggaataaaga
    18421 acctaacttg ctcaccgcta ttctcgacat aacggacagc gaattaaaag aggatttatt
    18481 gcaaagtctg atggattcac taggttctaa caaacatgta ctacccgaag tctgcatctg
    18541 ctttttatcc cttttagcag aacaagattt tccacatttt caggagttgt ttttattttt
    18601 cgccaatatg ttattgcact atcaccaatt tatgaaaccc aatgaaagtg atttgattga
    18661 cgtgttgatg ccagcatcat taagtgatga taaaattatc aaacatatgg cgcgcaagac
    18721 cctcaaactt tttgtaaaaa atgaaacgcc gccaaaagtt actcatgaag acctggtgaa
    18781 aaacaggcct cgctcccctg tcagaccacc tatacccgca acctccaaaa cgccagacct
    18841 ccctgaacgt cattaaaccg tgatgtgacc gactctctga cgcgtgaaag aatcagcgtc
    18901 agagaaacgg aaaacgcgat ccagatcaca aatgcattgt attcacatca ttaaccgttt
    18961 taagatcatt tcatcacttt ttcgcaactc acccgataat ctgttatgac aacaaacact
    19021 gtttcccgca aagtggcgtg gctacgggtc gttacgctgg cagtcgccgc cttcatcttc
    19081 aacaccaccg aatttgtccc agttggcctg ctctctgaca ttgcgcaaag ttttcacatg
    19141 caaaccgctc aggtcggcat tatgttgacc atttacgcat gggtagtagc gctaatgtca
    19201 ttgcctttta tgttaatgac cagccaggtt gaacggcgca aattactgat ctgcctgttt
    19261 gtggtgttta ttgccagcca cgtactgtcg tttttatcgt ggagttttac cgttctggtg
    19321 atcagtcgca ttggtgtggc ttttgcacat gcgattttct ggtcgattac ggcgtctctg
    19381 gcgatccgta tggctccggc cgggaagcga gcgcaggctt tgagtttaat agccaccggt
    19441 acagcactgg caatggtatt aggtttacct ctcgggcgca ttgtggggca gtatttcggt
    19501 tggcgaatga ccttcttcgc gattggtatc ggggcgctta tcaccctttt gtgcctgatt
    19561 aagttacttc ccttactgcc cagtgagcat tccggttcgc tgaaaagcct cccgctatta
    19621 ttccgccgcc cggcattgat gagcatttat ttgttaactg tggtggttgt caccgcccat
    19681 tacacggcat acagctatat cgagcctttt gtgcaaaaca ttgcgggatt cagcgccaac
    19741 tttgccacgg cattactgtt attactcggt ggtgcgggca ttattggcag cgtgattttc
    19801 ggtaaactgg gtaatcagta tgcgtctgcg ttggtgagta cggcgattgc gttgttgctg
    19861 gtgtgcctgg cactgctgct acctgcggcg aacagtgaaa tacacctcgg ggtgctgagt
    19921 attttctggg ggatcgcgat gatgatcatc gggcttggta tgcaggttaa agtgctggcg
    19981 ctggcaccag atgctaccga cgtcgcgatg gcgctattct ccgggatatt taatattgga
    20041 atcggcgcgg gtgcgttggt aggtaatcag gtcagtctgc actggtcaat gtcgatgatt
    20101 ggttatgtgg gcgcggtgcc tgcttttgcc gcgttaatat ggtcaatcat catttttcgc
    20161 cgctggccag tgacactcga agaacagacg caatagttga aaggcccatt cgggcctttt
    20221 ttagtggtac gttttaatga tttccaggat gccgttaata ataaactgca cccccataca
    20281 taccagcagg aatcccatca gacgggagat cgcttcaatg ccacccttgc ccaccagccg
    20341 cataatcgcg ccggagctgc gtaggcttcc ccacaaaata accgccacca ggaaaaagat
    20401 cagcggcggc gcaaccatca gtacccaatc agcaaaggtt gaactctgac gcactgtgga
    20461 cgccgagcta ataatcatcg ctatggttcc cggaccggcg gtacttggca ttgccagtgg
    20521 tacaaaagca atattggcgc tgggttcatc ttccagctct tccgacttgc ttttcgcttc
    20581 cggtgaatca atcgctttct gttgcggaaa gagcatccga aaaccgataa acgcgacgat
    20641 taagccgcct gcaattcgca gaccgggaat cgaaatgcca aatgtatcca tcaccagttg
    20701 cccggcgtaa tacgccacca tcatgatggc aaagacgtac accgaggcca tcaacgactg
    20761 acgattacgt tcggcactgt tcatgttgcc tgccaggcca agaaataacg cgacagttgt
    20821 taatgggtta gctaacggta gtaacaccac cagccccagg ccaattgctt taaataaatc
    20881 taacattggt ggttgttatc ctgtgtatct ggtttatcag cgaaaagtat aaggggtaaa
    20941 caacgataaa gtgtcactct ttagctaacc ttgcatcgca ctgaccaaaa cttgaaccga
    21001 tttagcaaaa cgtggcatcg gtcaattcat tcatttgact tatacttgcc tgggcaatat
    21061 tatcccctgc aactaattac ttgccagggc aactaatgtg aaaagtacca gcgatctgtt
    21121 caatgaaatt attccattgg gtcgcttaat ccatatggtt aatcagaaga aagatcgcct
    21181 gcttaacgag tatctgtctc cgctggatat taccgcggca cagtttaagg tgctctgctc
    21241 tatccgctgc gcggagtgta ttactccggt tgaactgaaa aaggtattgt cggtcgacct
    21301 gggggcgctg acccgtatgc tggatcgcct ggtctgtaaa ggctgggtgg aaaggttgcc
    21361 gaacccgaat gacaagcgcg gcgtactggt aaaacttacc accagcggcg cggcaatatg
    21421 tgaacaatgc catcaattag ttggccagga cctgcatcaa gaattaacaa aaaacctgac
    21481 ggcggacgaa gtggcaacac ttgagcattt gcttaagaaa gtcctgccgt aaacaaaaaa
    21541 agaggtatga cgatgtccag acgcaatact gacgctatta ccattcatag cattttggac
    21601 tggatcgagg acaacctgga atcgccactg tcactggaga aagtgtcaga gcgttcgggt
    21661 tactccaaat ggcacctgca acggatgttt aaaaaagaaa ccggtcattc attaggccaa
    21721 tacatccgca gccgtaagat gacggaaatc gcgcaaaagc tgaaggaaag taacgagccg
    21781 atactctatc tggcagaacg atatggcttc gagtcgcaac aaactctgac ccgaaccttc
    21841 aaaaattact ttgatgttcc gccgcataaa taccggatga ccaatatgca gggcgaatcg
    21901 cgctttttac atccattaaa tcattacaac agctagttga aaacgtgaca acgtcactga
    21961 ggcaatcatg aaaccacttt tatccgcaat agcagctgcg cttattctct tttccgcgca
    22021 gggcgttgcg gaacaaacca cgcagcagtt tgttacttcc tgtgccaatg tcgtggttgt
    22081 tcccccatcg caggaacaac caccgtttga tttaaatcac atgggtactg gcagtgataa
    22141 gtcggatgcg ctcggcgtgc cctattataa tcaacacgct atgtagtttg ttctggcccc
    22201 gacatatcgg ggcttattaa cttcccactt ttaccgcttt acgccaccgc aagccaaata
    22261 cattgatata cagcccggtc ataatgagca ccgcaccgaa aaattgcagg cccgttaagc
    22321 gttcatccag caatagtgcc gcacttgcca gtccaactac aggcaccagt aacgataacg
    22381 gtgcaacccg ccaggtttca tagcgtccca gtaacgtccc ccagatccca taaccaacaa
    22441 ttgtcgccac aaacgccaga tacatcagag acaagatggt ggtcatatcg atagtaacca
    22501 gactgtgaat catggttgcg gaaccatcga gaatcagcga ggcaacaaag aagggaatga
    22561 ttgggattaa tgcgctccag attaccagcg acatcaccgc cggacgcgtt gcgtgcgaca
    22621 tgatcttttt attgaagatg ttgccacacg cccaactaaa tgctgccgcc agggtcaaca
    22681 taaagccgag catcgccaca tgctgaccgt tcagactatc ttcgattaac accagtacgc
    22741 caaaaatcgc taaggcgatc cccgccaatt gtttgccatg cagtcgctcc ccgaaagtaa
    22801 acgcgccaag cacgatagta aaaaacgcct gtgcctgtaa caccagcgaa gccagtccag
    22861 caggcatacc aaagttaatg gcgcagaaca gaaaggcaaa ctgcgcaaaa ctgatggtta
    22921 atccataccc cagcagcaaa ttcagtggta ctttcggtcg tgcgacaaaa aagatagccg
    22981 gaaaagcaac cagcataaag cgcaaaccgg ccaacatcag cggtggcatg ttatgaagcc
    23041 ccactttgat gaccacaaaa tttagccccc atacgaccac taccagtagc gccaacaccc
    23101 catcttttcg cgacattcta ccgcctctga atttcatctt ttgtaagcaa tcaacttagc
    23161 tgaatttact tttctttaac agttgattcg ttagtcgccg attacgacgg cattaatgcg
    23221 caaataagtc gctatacttc ggatttttgc catgctattc ctttacatct ctaaaacaaa
    23281 acataacgaa acgcactgcc ggacagacaa atgaacttat ccctacgacg ctctaccagc
    23341 gcccttcttg cctcgtcgtt gttattaacc atcggacgcg gcgctacgct gccgtttatg
    23401 accatttact tgagtcgcca gtacagcctg agtgtcgatc taatcggtta tgcgatgaca
    23461 attgcgctca ctattggcgt cgtttttagc ctcggttttg gtatcctggc ggataagttc
    23521 gacaagaaac gctatatgtt actggcaatt accgccttcg ccagcggttt tattgccatt
    23581 cctttagtga ataacgtgac gctggtggtg ctcttttttg cccttattaa ctgcgcctat
    23641 tccgtttttg ctaccgtgtt gaaagcctgg tttgccgaca atctttcctc caccagcaaa
    23701 acgaaaatct tctcaatcaa ctacaccatg ctcaacattg gctggaccat cggtccgccg
    23761 ctcggcacgc tgttggtgat gcagagcatc aatctgccct tttggctggc agctatctgt
    23821 tccgcgtttc ccatgctttt cattcaaatt tgggtaaagc gcagcgagaa aatcatcgcc
    23881 acggaaacag gcagtgcctg gtcgccgaaa gttttattac aagataaagc actgttgtgg
    23941 tttacctgct ctggttttct ggcttccttt gttagtggcg catttgcttc atgcatttca
    24001 caatatgtga tggtgattgc tgatggggat tttgccgaaa aggtggtcgc ggttgttctt
    24061 ccggtgaatg ccgccatggt agttacgttg caatattccg tgggccgccg acttaacccg
    24121 gctaacatcc gcgcgctgat gacagcaggc accctctgtt tcgtcatcgg tctggttggt
    24181 tttatttttt ccggcaacag cctgctaatg tggggtatgt cagctgcggt atttactgtc
    24241 ggtgaaatca tttatgcgcc gggcgagtat atgttgattg accatattgc gccgccagga
    24301 atgaaagcca gctatttttc cgcccagtct ttaggctggc ttggtgctgc gattaaccca
    24361 ttagtgagtg gcatagtact taccagtctg ccgcctttct cgctgtttat catcttagcg
    24421 ttggtgatcg ttgctgcgtg ggtgctgatg ttaaaaggaa ttcgtgcaag accgtggggg
    24481 cagcccgcgc tttgttgatt taagtcgaac acaataaaaa tttaattcag ccttcgttta
    24541 ggttacctct gctaatatct ttctcattga gatgaaaatt aaggtaagcg aggaaacaca
    24601 ccacaccata aacggaggca aataatgctg ggtaatatga atgtttttat ggccgtactg
    24661 ggaataattt tattttctgg gtttctggcc gcgtatttca gccacaaatg ggatgactaa
    24721 tgaacggaga taatccctca cctaaccggc cccttgttac agttgtgtac aaggggcctg
    24781 atttttatga cggcgaaaaa aaaccgccag taaaccggcg gtgaatgctt gcatggatag
    24841 atttgtgttt tgcttttacg ctaacaggca ttttcctgca ctgataacgg atcgttgaca
    24901 cagtagcatc agttttctca atgaatgtta aacggagctt aaactcggtg aatcacgttt
    24961 tgttcgtcaa taaacataca gcgatttctt ccggtttgct taccctcata cattgcccgg
    25021 tccgctcttc caatgaccac atccagaggc tcttcaggaa atgcgcgact cacacctgct
    25081 gtcacggtaa tgttgatatg cccttcagaa tgtgtgatgg catggttatc gactaactgg
    25141 caaattctga tacctgcacg acatgcttct tcatcattat ccgctttgac aataatgata
    25201 aattcttcgc ccccgtagcg ataaaccgtt tcgtaatcac gcgtccaact ggctaagtaa
    25261 gttgccaggg tgcgtaatac tacatcgccg attaaatgcc cgtaggtatc attaaccaat
    25321 ttaaatcggt caatatccaa caacattaaa taaagattca gaggctcagc gttgcgtaac
    25381 tgatgatcaa aggattcatc aagaacccga cgacccggca atcccgtcaa aacatccata
    25441 ttgctacgga tcgtcagcaa ataaattttg taatcggtta atgccgcagt aaaagaaagc
    25501 aacccttcct gaaaggcgtc gaaatgcgcg tcctgccagt gattttcaac aatagccaac
    25561 attaattccc gaccacagtt atgcatatgt tgatgggcag aatccattag ccgaacgtaa
    25621 ggtaattcat cgttatcgag tggccccaga tgatcaatcc accgaccaaa ctggcacagt
    25681 ccataagaat ggttatccgt tatttctggc ttactggcat ctctcgcgac cacgctgtga
    25741 aacatactta ccagccactg gtagtgggca tcgatagcct tattgagatt taacaagatg
    25801 gcatcaattt ccgttgtctt cttgatcatt gccactcctt tttcacagtt ccttgtgcgc
    25861 gctattctaa cgagagaaaa gcaaaattac gtcaatattt tcatagaaat ccgaagttat
    25921 gagccatctc tgagataaca ttgtgattta aaacaaaatc agtagataaa aaagtgttta
    25981 attctgtaaa ttaactctgc attatcgcaa ttaaaaggat gacaaatagc ataacccaat
    26041 accctaatgg cccagtagtt caggccatca ggctaattta tttttatttc tgcaactgag
    26101 tgacccgaac gacggccggc gcgcttttct tatccagact gccgctaatg ttgatcatct
    26161 ggtccggctg aacttctcgt ccatcaaaga cggccgcagg aataacaaca ttaatttcac
    26221 cgctcttatc gcgaaaaacg taacggtcct ctcctttgtg agaaatcaaa ttaccgcgta
    26281 gtgaaaccga agcgccatcg tgcatggttt ttgcgaaatc aacggtcatt ttttttgcat
    26341 cgtcggttcc gcgatagcca tcttctattg catgaggcgg cggtggcgct gcatcctgtt
    26401 ttaaaccgcc cgggtcatct gccaacgcat aaggcatgac aagaaaactt gctaatacaa
    26461 tggcctgaaa tttcatactg actccttaat tgcgtttggt ttgacttatt aagtctggtt
    26521 gctattttta taattgacaa ttaagattac ttccaattgt tataaggcat ttaaaatcag
    26581 gtaactagct gtcaaatatt cagagaattt aactcactaa ggttaagaag aagattaaag
    26641 agtcttaaac atatttcaga ataatcagat ttataaattt gaaaattatt ataacggaag
    26701 ggtatacaaa aaaagtaatt ttgctggcga ctgcgaaacg gcattcgcat tagcggtgaa
    26761 gtttgccctc gcccagctgc tgcaattact gctataacga ggctggtctg gcgataaatc
    26821 caggccagcc attggtggtg tttatacgtt caagccacga tgttgcagca tcggcataat
    26881 ctgaggtgcc ttaccgcgcc attgtcgata caggcgttcc agatcctcgc tgttacctct
    26941 ggaaaggatc gcctcgcgaa aacgcagccc attttcacgc gttaatccgc cctgctcaac
    27001 aaaccactga taaccatcat cggccaacat ttgcgtccac agataagcgt aataacccgc
    27061 ggcatatccg ccaccaaaaa tatgggcgaa ataactgctg cgatagcgtg gcggtatagc
    27121 gggaagatcc atattttccg ccaccagcgc ccgcaattcg aaatcatcga catcctgcat
    27181 tgcttcgttt tcttccaggc aatgccagcg catatcgaga agtgcggcgc taagcagttc
    27241 gctcatctca taccctttat tgaacaggct ggcattacgc attttctgtt gcagttcgtc
    27301 aggcattgct gccccgctct gataatgccg ggcgtagcga gcgaatacct gcggatgcgt
    27361 tgcccagtgt tcgttgattt gcgacggaaa ttcgacaaaa tcacgcggcg tgttggtgcc
    27421 ggaaagcgta gcataacgct ggcaggcaaa caggccgtgc agcgtatgac caaattcatg
    27481 gaataaggtt attacatcat cccagagtaa caacgcaggc tccccagcag cgggtttctg
    27541 ataattgcag acgttataaa ttaccggatg cgtttcatta agcgttgatt gctcaacaaa
    27601 attgcccatc catgcaccgc cgctttttga atcacgggcg aagaaatcac cgtaaaataa
    27661 cgccagcccc acgccattat gatcaaaaat ttcccacacc cgaacgtcag gatggtagac
    27721 aggaatatca aaacgttcga caaacttaat accgaagagc tgattcgcag tccagaatac
    27781 accttcattc aacaccgtgt ttaattcaaa atatggcttg agctgcgatt catcgagatc
    27841 gaatttctca cgtcttacct gctcggcata aaatgcccag tcccacggct gcgcgctaaa
    27901 cccgccctgc tgcttatcga taaccgcctg tatggaggct aattcatcgc tcgcacgttg
    27961 acgcgccgct ggaacaattt cccgcataaa gttgagcgct gcttctggcg tttttgccat
    28021 ctgatcggcg attttccatg cggcataatg aggaaaacca agcagtttcg cctgctgcgc
    28081 gcggatctcc accagacgtt gaatgatagc gcgggtatca ttggcatcat ttttttccgc
    28141 tcgcatccag cccgcagtaa acagtttttc acgcgtcgcg cgatcgcaca gttcagcaag
    28201 cgctggttgt tgggtggtat tcagcagcgg aatcagccat ttgttataca gacctttctc
    28261 gcgagccgcc tctgccgcca gcgcaatctc ttgctcactc attcctgcca gctgcgcgat
    28321 atcgttcaca accagaccgc cggatttatt tgctgccagt aaccgctggt taaactggct
    28381 ggtcagggtc gcagcttctg tattcagtac ttttaatttt gctttatcag cttgcttaag
    28441 tttggctccg gcaaggacaa aacgttgatg aatcacctcc accaggcgga tggattcact
    28501 atcaagcccc agggattcac ggcgctgcca gacagcatct acccgcgcga ataattcccc
    28561 gttcagatag atatcattcg caagttccgc cagttcagcg gaaaactgtt catcaagacg
    28621 ctgtaattca tcattggtat gcgccgcagt catcgcaaaa aagacgctgg taacgcgggt
    28681 aagtaattct ccgctttgtt ccagtgccag aatagtattg ttgaaatcag gtgtttgcgg
    28741 gttaagcgcg atggcagcaa tttctgcccg cttttgctgc attccctcat cgaatgccgg
    28801 gcgatagtga tgattggcaa tttgatcaaa atggggagcc agatacggca gtgtgctttg
    28861 cacaaggaaa ggattcattg ttgtcatttt cttctcctga acgcgaggtg ttccatagcg
    28921 taggcttact gataacggag tgcaatcttg caaaccagta ttacccgctc ttaagcatca
    28981 cgtgctatgt tattgacaca caaaagcgtt gaggaacagt gagatgatcg ttttagtaac
    29041 tggagcaacg gcaggttttg gtgaatgcat tactcgtcgt tttattcaac aagggcataa
    29101 agttatcgcc actggccgtc gccaggagcg gttgcaggag ttaaaagacg aactgggaga
    29161 taatctgtat atcgcccaac tggacgttcg caaccgcgcc gctattgaag agatgctggc
    29221 atcgcttcct gccgagtggt gcaatattga tatcctggta aataatgccg gtctggcgtt
    29281 gggcatggag cctgcgcata aagccagcgt tgaagactgg gaaacgatga ttgataccaa
    29341 caacaaaggc ctggtatata tgacgcgcgc cgtcttaccg ggtatggttg aacgtaatca
    29401 tggtcatatt attaacattg gctcaacggc aggcagctgg ccgtatgccg gtggtaacgt
    29461 ttacggtgcg acgaaagcgt ttgttcgtca gtttagcctg aatctgcgta cggacctgca
    29521 tggtacggcg gtgcgcgtca ccgacatcga accgggtctg gtgggtggca ccgagttttc
    29581 caatgtccgc tttaaaggcg atgacggtaa agcggaaaaa acctatcaaa ataccgttgc
    29641 attgacgcca gaagatgtca gcgaagccgt ctggtgggtg tcaacgctgc ctgctcacgt
    29701 caatatcaat accctggaaa tgatgccggt tacccaaagc tatgccggac tgaatgtcca
    29761 ccgtcagtaa tttttatacc cggcgtaact gccgggttat tgcttgtcac aaaaaagtgg
    29821 tagactcatg cagttaactc actcacaagc aagaacgaat gaccgtcgaa acgcaactta
    29881 atcccacaca gcctgtcaat cagcagattt atcgtattct tcgtcgcgac attgtccatt
    29941 gcctgattgc tccaggcaca ccgttgtcgg aaaaagaagt ttctgttcgt ttcaatgtgt
    30001 cacgccagcc ggttcgtgaa gcctttatta aactggcgga aaacggcctg attcaaattc
    30061 gtccgcagcg tggcagctac gtcaacaaaa tttccatggc ccaggtgcgc aacggcagtt
    30121 ttatccgtca ggccattgag tgcgcggtgg cgcgtcgggc ggcgagcatg attaccgaaa
    30181 gccagtgcta ccaactggaa caaaatcttc accagcaacg cattgccatt gagcgcaagc
    30241 aactggatga tttttttgaa cttgatgaca acttccatca actcctgacc cagattgccg
    30301 actgtcaact ggcgtgggaa accattgaga acctgaaagc gaccgttgat cgcgtgcgct
    30361 atatgagttt cgaccacgtt tctccaccag aaatgctgtt acgccagcat cttgagattt
    30421 tctctgccct gcaaaaacgt gatggcgatg cggtagaacg tgcaatgacg caacatttgc
    30481 aggaaatcag cgaatctgtg cgccagatcc gccaggaaaa cagcgactgg tttagcgaag
    30541 agtaattcat ttcctctcat cccatccggg gtgagagtct tttcccccga cttatggctc
    30601 atgcatgcat caaaaaagat gtgagcttga tcaaaaacaa aaaatatttc actcgacagg
    30661 agtatttata ttgcgcccgt tacgtgggct tcgactgtaa atcagaaagg agaaaacacc
    30721 tatgacgacc tacgatcgta accgtaacgc aatcaccact ggcagccgtg ttatggttag
    30781 cggcaccggt cacactggca agatcctgtc gattgatact gaaggtctga ccgctgagca
    30841 aatccgccgc ggaaaaaccg tagttgttga aggttgtgaa gagaaactgg cacctctgga
    30901 cctgattcgt ctcggcatga actaagcgtg tgaatgccgc cgatggcggc attgcttttt
    30961 ttacttcacg gaatatttcg ccacggtcgc tttcgcacca tgcgctaata aagacaagta
    31021 cgcttccgtc acttttgcag taaacaagct attgtctggc aaatcatcac caaagatcgc
    31081 cttaatcgcc agcaatgact ggacgcgcgc tttcccttcg gcactacttt gtacagcctt
    31141 ctgaataaca ggtaacagtg ggtcactgat ttctatcgga tttccctgtt catcaacacc
    31201 accgacataa cgcatccaac ccgcgacgcc tagcgccagc agatcgaact tgctgtcatg
    31261 cgccagatgc cagcgaacag aatccaacat ccgctgtggc aatttctggc tgccatccat
    31321 cgcaatctgc caggttcgat gacgtagcgc cgggttgcta tagcgttcaa ttaatcggtt
    31381 agcgtaatct tgcaaatcaa cgccctgcac tttcaacgtc ggcgcttgtt catgcaacat
    31441 caaggcatac gctgcatgac gataatgttc atcttccatg cagtcattaa tgtgctgata
    31501 tccggcaaga taacccagat acgccaggaa tgaatgactg ccgttgagca tgcgcaactt
    31561 catctcttca taaggcagca catcactaac cagttcggct cccgcttttt cccattccgg
    31621 acgtccggca acaaagttat cttctattac ccactggcgg aaaggttcac aggcaacgcc
    31681 agcaggatcg cgcacaccgg taagttgttc gattttcgcc agcgtatcct ctgtcactgc
    31741 gggcacaata cggtccacca ttgttgatgg gaaagtcacg ttttcttcga tccattgtgc
    31801 cagttttaca tcaacagctt gcgcgtagga agtgacaacg tcacgcataa catgaccgtt
    31861 ttctggcatg ttgtcacatg acatgacggt aaatgcggga agtcctgccg ctttacggcg
    31921 agccagcgcc tcgacaatca cccctattgc agttttcggc tggtggggat tttgtacatc
    31981 ggcaacgacc atcgggtgat cgggcattaa ctgtccggtc gccggagagt ggaaataccc
    32041 tttttcggtg attgtcagag agacaatcgc gatttgcggt tcacacatcg cagccaacac
    32101 ggtttctaag ccatcaatct gtacgtgcaa ggctttttta acgacgccaa cgacgcgagc
    32161 cgtccacgca tcggccgaca tttccgcaac ggtataaaga ttatcttgct gttgtaaatc
    32221 ggcaatttgc tgttcgccgc cgattaaatt gacctcataa tatccccagt cactgaaatg
    32281 ttccgtagca agaatatcgg catacacacc ctgatgcgca cggtgaaatg caccaaagcc
    32341 taaatgaaca attcttgggg ccaggttatt acgatcataa acagggagcg tcgcttttgc
    32401 tgataacaaa ttatttccca taacaattcc ttaaatttaa atatggcaag ctgcatgttt
    32461 tgttatatga ataaaaaatc ccctctccgg taagagaagg gatggaggat ttacagactt
    32521 cttgaaggtt gcgctgctgt tacaacacgc ggttgatctt ccgcggcatc ttccagtgca
    32581 cttaaatcac ggtctttcac ttctggcatt ttcagcgcag agattaaacc aatcactgaa
    32641 tatgccatga tcataatggc gatcggatac caggattccg tcatggtgca gaaaataccc
    32701 gccaggatag gaccaaaacc ggaagcgata agaccaccaa tttctttaga aatagccatc
    32761 cgggtaaagc ggtttttaca gccgaacatt tctgccatgg taatgttttc cagagcaaat
    32821 aatcccagca ccgcacagtt atgaatcaca atcagtgcaa ccataatggt gctcggggca
    32881 tagcttttat ctacgatgat agaaagcatt ggccacgcca gcacaatcgc agaggtattc
    32941 ataataatat acgggatccg gcgacctatt ttatcggata accaaccaag gaacggaatg
    33001 gtcataaagc cgagaatcga actgatcatc aatgcatctg ttggaattgc tttgttaaac
    33061 aataacgtct gcactaaata gcctgcaagg aaagtctgaa ttaaacctga gttaccagcc
    33121 tgaccaaaac gcagccctgt tgccagccag aaggatttgc tctggaacat gctaccagca
    33181 ggtgcaggtt ttgctgtcgg ttgattgctg tcgttaacct tctcaaagac cgggctttct
    33241 ttcagattca tacgcaacca gatagcaaag accatcacga caacgctcgc caggaacggt
    33301 atacgccatc cccacgccaa cagttcctct ttactgagaa tgaagaacat aaaggcccag
    33361 attgccgttg cgctcaaggt tccgcagtta gtccccatag caacaaatga ggagataatt
    33421 ccgcgcttac cttttggcgc atattccgcc agcatcgtac cggcaccgga aatttccgca
    33481 cctgcaccca atccctgaat aatacgcagc gtcaccagca agatgggtgc aaaaacacca
    33541 atctgtgcat aggtcggtaa cacaccaatt aaggtggtac agatccccat catggtgatg
    33601 gtaataaaga gtactttttt acgccctatt ctgtcgccca ttttgccgaa aataaatgct
    33661 ccgacaatac gcgccacata acctgcaccg taggttccca ttgccagaat taacgccatt
    33721 gccgttgatg attcaggaaa aaatatttca tgaaacacta acgctgcgcc gagcgaatat
    33781 aactggaaat ccataattca caggtgtttt ttcccatcct gtggtttcct tggcgttttc
    33841 taggtttttt cagatagttg cattttttaa aaagcatcct aagttcgatc tcagtgtcta
    33901 tctggggcct atttctgtcc catatatgcc ccaaaaaaaa ctccccaaca gataagtagt
    33961 tttttcatgg atttatgcgt aaaatcaaga acggctggaa atcattcaat actcacacta
    34021 tcgaaaaatt taccagccaa ccgcagcacg ttcttgcata aggcgtgtct gcggtttttc
    34081 aactattcag atacatcact cccatcacat tcattcctcc gcatcaaagg catataggct
    34141 atatcacctt gatatttttc tttttcagat aaaaactgtt atctatgtat acttttaaac
    34201 ccaatccgtg tagagtctct gcataagata gtttacagtt gccgcttcag cttgcgccat
    34261 aaaccgcctg atttttgctg ccacctgtta gcattcctgt atacctgaaa cgacaatgtt
    34321 tatctacgaa ctttaagaac acccaagata aaaattgtca actatatcat atataacaca
    34381 ttactaattc gaggctatat gaacagcata ctgataatca catctctcct tatcatattc
    34441 agcattttta gtcatgccct aataaaatta gggattggca tatccaataa cccagacaaa
    34501 accgatgtat aagtcaacat atcctgaatc agacatacaa tatcgcaatg aaaatcaata
    34561 atattttaag gaatatcttc atgaaatcaa aagacaccct aaagtggttc cctgcgcagc
    34621 ttcctgaagt aagaattatc ctaggggatg ctgtagtgga agtagcaaaa cagggaagac
    34681 ctatcaatac cagaacattg cttgattaca ttgaaggaaa cataaagaaa aaatcatg
//
LOCUS       DADXDL010000054        34291 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.054, whole genome shotgun sequence.
ACCESSION   DADXDL010000054 DADXDL010000000
VERSION     DADXDL010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 34291)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 34291)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..34291
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.054"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..888
                     /locus_tag="IRB70_002858"
     CDS             <1..888
                     /locus_tag="IRB70_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBC0632747.1"
                     /translation="AKVGGYFNNLRAANQAFVMERRDHAGGDGQTLNLRVIGGRYHYT
                     AAGQLAQHEDTSTVQLSGNLFSGHWGDDGEWMLGIVGGYSDNQGDSRSNMSGTRADNQ
                     NHGYAVGLTSSWYQHGNQKQGVWLDSWLQYAWFNNDVSEQDDGVDRYHSSGIIASLEA
                     GYQWLPGHGVVIEPQAQVIYQGVQQDDFTAANHARVSQSQGDDIQTRLGLHSEWRTAV
                     HVIPTLDLNYYHDPHATEIEEDGSTISDDGVKQRGEIKVGVTGNISQRVSLRGSVAWQ
                     KGSDDFAQTAGFLSMTVKW"
     gene            complement(1029..1751)
                     /locus_tag="IRB70_002859"
     CDS             complement(1029..1751)
                     /locus_tag="IRB70_002859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 3-demethylubiquinone
                     3-O-methyltransferase/2-octaprenyl-6-hydroxy phenol
                     methylase"
                     /protein_id="HBC0632748.1"
                     /translation="MNAEKSPVNHNVDHEEIAKFEAVASRWWDLEGEFKPLHRINPLR
                     LGYIAERAGGLFGKKVLDVGCGGGILAESMAREGATVTGLDMGFEPLQVAKLHALESG
                     IQVDYVQETVEEHAAKHAGQYDVVTCMEMLEHVPDPQSVVRACAQLVKPGGDVFFSTL
                     NRNGKSWLMAVVGAEYILRMVPKGTHDVKKFIKPAELLGWVDQTSLKERHITGLHYNP
                     ITNSFKLGPGVDVNYMLHTQNK"
     gene            1898..4525
                     /gene="gyrA"
                     /locus_tag="IRB70_002860"
     CDS             1898..4525
                     /gene="gyrA"
                     /locus_tag="IRB70_002860"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit A"
                     /protein_id="HBC0632749.1"
                     /translation="MSDLAREITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPV
                     HRRVLYAMNVLGNDWNKAYKKSARVVGDVIGKYHPHGDLAVYNTIVRMAQPFSLRYML
                     VDGQGNFGSIDGDSAAAMRYTEIRLAKIAHELMADLEKETVDFVDNYDGTEKIPDVMP
                     TKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISIEGLMEHIPGPDFP
                     TAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTGRETIIVHEIPYQVNKARLIEK
                     IAELVKEKRVEGISALRDESDKDGMRIVIEVKRDAVGEVVLNNLYSQTQLQVSFGINM
                     VALHHGQPKIMNLKDIIAAFVRHRREVVTRRTIFELRKARDRAHILEALAVALANIDP
                     IIELIRHAPTPAEAKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYL
                     TEQQAQAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREELEL
                     VREQFGDKRRTEITANSADINLEDLITQEDVVVTLSHQGYVKYQPLSEYEAQRRGGKG
                     KSAARIKEEDFIDRLLVANTHDHILCFSSRGRVYSMKVYQLPEATRGARGRPIVNLLP
                     LEQDERITAILPVTEFEEGVKVFMATANGTVKKTVLTEFNRLRTAGKVAIKLVEGDEL
                     IGVDLTSGEDEVMLFSAEGKVVRFKESSVRAMGCNTTGVRGIRLGEGDKVVSLIVPRG
                     DGAILTATQNGYGKRTAVAEYPTKSRATKGVISIKVTERNGLVVGAVQVDDCDQIMMI
                     TDAGTLVRTRVSEISIVGRNTQGVILIRTSEDENVVGLQRVAEPVDEEDLDTIDGSAA
                     EGDDEIAPEVDVDDEPEEE"
     gene            4674..6362
                     /locus_tag="IRB70_002861"
     CDS             4674..6362
                     /locus_tag="IRB70_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416733.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2138 domain-containing protein"
                     /protein_id="HBC0632750.1"
                     /translation="MSGEKKAKGWRFYGLVGFGAIALLSAGVWALQYSGSGPEKTLSP
                     LVVHNNLQIDLNEPDLFLDSDSLSQLPNDLLTIPFLHDVLSEDFVFYYQNHADRLGIE
                     GSIRRIVYEHDLTLKDKLFSSLLDQPAQAALWHDKQGHLSHYMVLIQRSGLSKLLEPL
                     LFAATSDSQLSKTEISSIKINSETIPVYQLRYNGNNVLMFATYQDKILAFSSSDMLFK
                     DDQQDTEATAIASDLLSGKKRWQASFGLEERAAEKTPVRQRIVVSARLLGFGYQRLMP
                     SFAGVRFEMSNDSWHSFVALNDESASVDASFDFTPVWNSMPAGASFCVAVPYSHGIAE
                     EMLSHISQENDKLNGALDGAAGLCWYEDSKLQTPLFVGQFDGSAEQAQLPGKLFTQNI
                     GAHESKAPEGVLPVNQTQQGEAQIWRREVSSRYGQYPKAQAAQPDQLMSDYFFRVSLA
                     MQNKTLLFSLDDTLVNNALQTLNKTRPAMVDVIPTDGIVPLYINPQGVAKLLRNETLT
                     SLPKNLEPVFYNAAQTLLMPKLDALSQQPRYVMKLAQMEPGAAWQWLPITWQPL"
     gene            6359..6982
                     /locus_tag="IRB70_002862"
     CDS             6359..6982
                     /locus_tag="IRB70_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311139.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1175 domain-containing protein"
                     /protein_id="HBC0632751.1"
                     /translation="MRHGLLALICWLCCVVAHSEMLNVEQSGLFRAWFVRIAQEQLRQ
                     GPSPRWYQQDCAGLVRFSANEALKIHDSKWLKSNGIASQYLPPEMTLTPEQRQLAQNW
                     NQGNGKTGPYVTAINLIQYNSQFIGQDINQALPGDMIFFDQGDAQHLMVWMGRYVIYH
                     TGSATKTDNGMRAVSLQQLMTWKDTRWIPNDSNPNFIGIYRLNFLAR"
     gene            7006..11520
                     /locus_tag="IRB70_002863"
                     /pseudo
     CDS             7006..11520
                     /locus_tag="IRB70_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000536590.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-2-macroglobulin family protein"
     gene            11521..13170
                     /locus_tag="IRB70_002864"
     CDS             11521..13170
                     /locus_tag="IRB70_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaQ family protein"
                     /protein_id="HBC0632752.1"
                     /translation="MNWRRIVWLLALVTLPTLAEETSLQLALRGAQHDQLYQLSSSGV
                     TKVSALPDTLTTPLGSLWKLYVYAWLEDTHQPEQPYQCRGNSPEEVYCCQAGESITRD
                     TALVRSCGLYFAPQRLHIGADVWGQYWQQRQAPAWLASLTTLKPETSVTVKSLLDSLA
                     TLPAQNKAQEVLLDVVLDEAKIGVASMLGSRVRVKTWSWFADNKQEIRQGGFAGWLTD
                     GTPLWVTGSGTSKTVLTRYATVLNRVLPVPTQVASGQCVEVELFARYPLKKIAAEKST
                     TAVKPGVLNGRYRVTFANGNHITFVSHGETTLLSEKGKLKLQSHLDREEYVARVLDRE
                     AKSTPPEAAKAMTVAIRTFLQQNANREGDCLTIPDSSATQRVSASPATTGARTMTAWT
                     QDLIYAGDPVHYHGSRATEGTLSWRQATAQAGQGERYDQILAFAYPDNSLSRWGAPRS
                     TCQLLPKAKAWLAKKMPQWRRILQGEMGYNEPDVFAVCRLISGFPYTDRQQKRLFIRN
                     FFTLQDRLDLTHEYLHLAFDGYPTGLDENYIETLTRQLLMD"
     gene            13175..13951
                     /locus_tag="IRB70_002865"
     CDS             13175..13951
                     /locus_tag="IRB70_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfaP family protein"
                     /protein_id="HBC0632753.1"
                     /translation="MRKIFLPLLLVALSPVAHSEGVQEVEIDAPLSGWHPAEGEDASF
                     SQSINYPASSVNMADDQNISAQIRGKIKNYAAAGKVQQGRLVVNGASMPQRIESDGSF
                     ARPYIFTEGSNSVQVISPDGQSRQKMQFYSTPGAGVIRARLRLVLSWDTDDTDLDLHV
                     VTPDGEHAWYGNTVLNNSGALDMDVTTGYGPEIFAMPAPVHGRYQVYINYYGGRSETE
                     LTTAQLTLITDEGSVNEKQETFIVPMRNAGELTLVKSFDW"
     gene            complement(14025..15209)
                     /gene="atoB"
                     /locus_tag="IRB70_002866"
     CDS             complement(14025..15209)
                     /gene="atoB"
                     /locus_tag="IRB70_002866"
                     /EC_number="2.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA acetyltransferase"
                     /protein_id="HBC0632754.1"
                     /translation="MKNCVIVSAVRTAIGSFNGSLASTSAIDLGATVIKAAIERAKID
                     SLHIDEVIMGNVLQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAI
                     QAGQAQSIVAGGMENMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGI
                     TAENVAKEYGITREMQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDE
                     FPKADSTTEALGALRPAFDKAGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARI
                     KSYASGGVPPALMGMGPVPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKTLGFD
                     SEKVNVNGGAIALGHPIGASGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIER
                     LN"
     gene            complement(15240..16562)
                     /locus_tag="IRB70_002867"
     CDS             complement(15240..16562)
                     /locus_tag="IRB70_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00366 family protein"
                     /protein_id="HBC0632755.1"
                     /translation="MIGRISRFMTRFVSRWLPDPLIFAMLLTLLTFVIALWLTPQTPI
                     SMVKMWGDGFWNLLAFGMQMALIIVTGHALASSAPVKSLLRTAASAAKTPVQGVMLVT
                     FFGSVACVINWGFGLVVGAMFAREVARRVPGSDYPLLIACAYIGFLTWGGGFSGSMPL
                     LAATPGNPVEHIAGLIPVGDTLFSGFNIFITVALIVVMPFITRMMMPKPSDVVSIDPK
                     LLMEEADFQKQLPKNAPPSERLEESRILTLIIGALGIAYLAMYFSEHGFNITINTVNL
                     MFMIAGLLLHKTPMAYMRAISAAARSTAGILVQFPFYAGIQLMMEHSGLGGLITEFFI
                     NVANKDTFPVMTFFSSALINFAVPSGGGHWVIQGPFVMPAAQALGADLGKSVMAIAYG
                     EQWMNMAQPFWALPALAIAGLGVRDIMGYCITALLFSGVIFVIGLTLF"
     gene            complement(16559..17209)
                     /gene="atoA"
                     /locus_tag="IRB70_002868"
     CDS             complement(16559..17209)
                     /gene="atoA"
                     /locus_tag="IRB70_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate CoA-transferase subunit beta"
                     /protein_id="HBC0632756.1"
                     /translation="MDAKQRIARRVAQELRDGDIVNLGIGLPTMVANYLPEGIHITLQ
                     SENGFLGLGPVTTAHPDLVNAGGQPCGVLPGAAMFDSAMSFALIRGGHIDACVLGGLQ
                     VDEEANLANWVVPGKMVPGMGGAMDLVTGSRKVIIAMEHCAKDGSAKILRRCTMPLTA
                     QHAVHMLVTELAVFRFIDGKMWLTEIADGCDLATVRAKTEARFEVAADLNTQRGDL"
     gene            complement(17209..17871)
                     /gene="atoD"
                     /locus_tag="IRB70_002869"
     CDS             complement(17209..17871)
                     /gene="atoD"
                     /locus_tag="IRB70_002869"
                     /EC_number="2.8.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate CoA-transferase subunit alpha"
                     /protein_id="HBC0632757.1"
                     /translation="MKTKLMTLQDATGFFRDGMTIMVGGFMGIGTPSRLVEALLESGV
                     RDLTLIANDTAFVDTGIGPLIVNGRVRKVIASHIGTNPETGRRMISGEMDVVLVPQGT
                     LIEQIRCGGAGLGGFLTPTGVGTVVEEGKQTLTLDGKTWLLERPLRADLALIRAHRCD
                     TLGNLTYHLSARNFNPLIALAADITLVEPDELVETGELQPDHIVTPGAVIDHIIVSQE
                     SK"
     gene            complement(18067..19452)
                     /gene="atoC"
                     /locus_tag="IRB70_002870"
     CDS             complement(18067..19452)
                     /gene="atoC"
                     /locus_tag="IRB70_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetoacetate metabolism transcriptional
                     regulator AtoC"
                     /protein_id="HBC0632758.1"
                     /translation="MTAINRILIVDDEDNVRRMLSTAFALQGFETHCANNGRTALHLF
                     ADIHPDVVLMDIRMPEMDGIKALKEMRSHETRTPVILMTAYAEVETAVEALRCGAFDY
                     VIKPFDLDELNLIVQRALQLQSMKKEIRHLHQALSTSWQWGHILTNSPAMMDICKDTA
                     KIALSQASVLISGESGTGKELIARAIHYNSRRAKGPFIKVNCAALPESLLESELFGHE
                     KGAFTGAQTLRQGLFERANEGTLLLDEIGEMPLVLQAKLLRILQEREFERIGGHQTIK
                     VDIRIIAATNRDLQAMVKEGTFREDLFYRLNVIHLILPPLRDRREDISLLANHFLQKF
                     SSENQRDIIDIDPMAMSLLTAWSWPGNIRELSNVIERAVVMNSGPIIFSEDLPPQIRQ
                     PVCNAGEAKTAPVGERNLKEEIKRVEKRIIMEVLEQQEGNRTRTALMLGISRRALMYK
                     LQEYGIDPADV"
     gene            complement(19449..21275)
                     /gene="atoS"
                     /locus_tag="IRB70_002871"
     CDS             complement(19449..21275)
                     /gene="atoS"
                     /locus_tag="IRB70_002871"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     AtoS"
                     /protein_id="HBC0632759.1"
                     /translation="MHYMKWIYPRRLRNQMILMAILMVIVPTLTIGYIVETEGRSAVL
                     SEKEKKLSAVVNLLNQALGDRYDLYIDLPREERIRALNAELAPITENITHAFPGIGAG
                     YYNKTLDAIITYAPSALYQNNVGVTIAADHPGREVMRTNTPLVYSGRQVRGDILNSMI
                     PIERNGEILGYIWANELTEDIRRQAWKMDVRIIIVLTAGLLISLLLIVLFSRRLSANI
                     DIITDGLSTLAQNIPTRLPQLPGEMGQISQSVNNLAQALRETRTLNDLIIENAADGVI
                     AIDRQGDVTTMNPAAEVITGYQRHELVGQPYSMLFDNTQFYSPVLDTLEHGTEHVALE
                     ISFPGRDRTIELSVTTSRIHNTHGEMIGALVIFSDLTARKETQRRMAQAERLATLGEL
                     MAGVAHEVRNPLTAIRGYVQILRQQTSDLIHQEYLSVVLKEIDSINKVIQQLLEFSRP
                     RHSQWQQVSLNALVEETLVLVQTAGVQARVDFISELDNELSPINADRELLKQVLLNIL
                     INAVQAISARGKIRIRTWQYSDSQQAISIEDNGCGIDLSLQKKIFDPFFTTKASGTGL
                     GLALSQRIINAHQGDIRVASLPGYGATFTLILPINPQGNQTV"
     gene            21442..24291
                     /gene="rcsC"
                     /locus_tag="IRB70_002872"
     CDS             21442..24291
                     /gene="rcsC"
                     /locus_tag="IRB70_002872"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416722.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     RcsC"
                     /protein_id="HBC0632760.1"
                     /translation="MKYLASFRTTLKASRYMFRALALVLWLLIAFSSVFYIVNALHQR
                     ESEIRQEFNLSSDQAQRFIQRTSDVMKELKYIAENRLSAENGVLSPRGRETQADVPAF
                     EPLFADSDCSAMSNTWRGSLESLAWFMRYWRDNFSAAYDLNRVFLIGSDNLCMANFGL
                     RDMPVERDTALKALHERINKYRNAPQDDSGSNLYWISEGPRPGVGYFYALTPVYLANR
                     LQALLGVEQTIRMENFFLPGTLPMGVTILDENGHTLISLTGPESKIKGDPRWMQERSW
                     FGYTEGFRELVLKKNLPPSSLSIVYSVPVDKVLERIRMLILNAILLNVLAGAALFTLA
                     RMYERRIFIPAESDALRLEEHEQFNRKIVASAPVGICILRTADGVNILSNELAHTYLN
                     MLTHEDRQRLTQIICGQQVNFVDVLTSNNTNLQISFVHSRYRNENVAICVLVDVSSRV
                     KMEESLQEMAQAAEQASQSKSMFLATVSHELRTPLYGIIGNLDLLQTKELPKGVDRLV
                     TAMNNSSSLLLKIISDILDFSKIESEQLKIEPREFSPREVMNHITANYLPLVVRKQLG
                     LYCFIEPDVPVALNGDPMRLQQVISNLLSNAIKFTDTGCIVLQVRADGDYLSIRVRDT
                     GVGIPAKEVVRLFDPFFQVGTGVQRNFQGTGLGLAICEKLISMMDGDISVDSEPGMGS
                     QFTVRIPLYGAQYPQKKGVEGLSGKRCWLAVRNASLCQFLETSLQRSGIVVTTYEGQE
                     PTPEDVLITDEVVSKKWQGRAVVTFCRRHIGIPLEKAPGEWVHSVAAPHELPALLARI
                     YLIEMESDDPANALPSTDKAVSDNDDMMILVVDDHPINRRLLADQLGSLGYQCKTAND
                     GVDALNVLSKNHIDIVLSDVNMPNMDGYRLTQRIRQLGLTLPVIGVTANALAEEKQRC
                     LESGMDSCLSKPVTLDVIKQTLTVYAERVRKSRDS"
     gene            complement(24377..25027)
                     /gene="rcsB"
                     /locus_tag="IRB70_002873"
     CDS             complement(24377..25027)
                     /gene="rcsB"
                     /locus_tag="IRB70_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator RcsB"
                     /protein_id="HBC0632761.1"
                     /translation="MNNMNVIIADDHPIVLFGIRKSLEQIEWVNVVGEFEDSTALINN
                     LPKLDAHVLITDLSMPGDKYGDGITLIKYIKRHFPSLSIIVLTMNNNPAILSAVLDLD
                     IEGIVLKQGAPTDLPKALAALQKGKKFTPESVSRLLEKISAGGYGDKRLSPKESEVLR
                     LFAEGFLVTEIAKKLNRSIKTISSQKKSAMMKLGVENDIALLNYLSSVTLSPADKD"
     gene            complement(25044..27716)
                     /gene="rcsD"
                     /locus_tag="IRB70_002874"
     CDS             complement(25044..27716)
                     /gene="rcsD"
                     /locus_tag="IRB70_002874"
                     /EC_number="2.7.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase RcsD"
                     /protein_id="HBC0632762.1"
                     /translation="MRQKETTATTRFSLLPGSITRFFLLLIIVLLVTMGVMVQSAVNA
                     WLKDKSYQIVDITHAIQKRVDTWRYVTWQIYDNIAATTSPSSGEGLQETRLKQDVYYL
                     EKPRRKTEALIFGSHDNSTLEMTQRMSTYLDTLWGAENVPWSMYYLNGQDNSLVLIST
                     LPLKDLTSGFKESTVSDIVDSRRAEMLQQANALDERESFSNMRRLAWQNGHYFTLRTT
                     FNQPGHLATVVAFDLPINDLIPPGMPLDSFRLEPDATATGDNDNEKEGTDSVSIHFNS
                     TKIEISSALNSTDMRLVWQVPYGTLLLDTLQNILLPLLLNIGLLALALFGYTTFRHFS
                     SRSTESVPSTAVNNELRILRAINEEIVSLLPLGLLVHDQESNRTVISNKIADHLLPHL
                     NLQNITTMAEQHQGIIQATINNELYEIRMFRSQVAPRTQIFIIRDQDREVLVNKKLKQ
                     AQRLYEKNQQGRMTFMKNIGDALKEPAQSLAESAAKLNAPEGKQLANQADVLVRLVDE
                     IQLANMLADDSWKSETVLFSVQDLIDEVVPSVLPAIKRKGLQLLINNHLKAHDMRRGD
                     RDALRRILLLLMQYAVTSTQLGKITLEVDQDESSEDRLTFRILDTGEGVSIHEMDNLH
                     FPFINQTQNDRYGKADPLAFWLSDQLARKLGGHLNIKTRDGLGTRYSVHIKMLAADPK
                     VEEEEERLLDDVCVMVDVTSAEIRNIVTRQLENWGATCITPDERLISQDYDIFLTDNP
                     SNLTASGLLLSDDESGVREIGPGQLCVNFNMSNAMQEAVLQLIEVQLAQEEVTESPLG
                     GDENAQLHASGYYALFVDTVPDDVKRLYTEAATSDFAALAQTAHRLKGVFAMLNLVPG
                     KQLCETLEHLIREKDVPGIEKYISDIDSYVKSLL"
     gene            28455..29549
                     /locus_tag="IRB70_002875"
     CDS             28455..29549
                     /locus_tag="IRB70_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HBC0632763.1"
                     /translation="MKVKVLSLLVPALLVAGAANAAEIYNKDGNKLDLYGKVDGLHYF
                     SDNDSKDGDKTYMRLGFKGETQVTDQLTGYGQWEYQIQGNEPESDNSSWTRVAFAGLK
                     FQDVGSFDYGRNYGVVYDVTSWTDVLPEFGGDTYDSDNFMQQRGNGFATYRNTDFFGL
                     VDGLDFAVQYQGKNGSAHGEGMTTNGRDDVFEQNGDGVGGSITYNYEGFGIGAAVSSS
                     KRTWDQNNTGLIGTGDRAETYTGGLKYDANNIYLAAQYTQTYNATRVGSLGWANKAQN
                     FEAVAQYQFDFGLRPSLAYLQSKGKNLGRGYDDEDILKYVDVGATYYFNKNMSTYVDY
                     KINLLDDNQFTRAAGINTDDIVALGLVYQF"
     gene            29661..30716
                     /gene="apbE"
                     /locus_tag="IRB70_002876"
     CDS             29661..30716
                     /gene="apbE"
                     /locus_tag="IRB70_002876"
                     /EC_number="2.7.1.180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase ApbE"
                     /protein_id="HBC0632764.1"
                     /translation="MEISFTRVALLAAALFFVGCDQKPQPAKTHATEVTVLEGKTMGT
                     FWRASIPGIDAKRSAELKEKIQTQLDADDQLLSTYKKDSALMRFNDSQSLSPWPVSEA
                     MADIVTTSLRIGAKTDGAMDITVGPLVNLWGFGPEQQPVQIPSQEQIDAMKAKTGLQH
                     LTVINQSHQQYLQKDLPDLYVDLSTVGEGYAADHLALLMEQEGISRYLVSVGGALNSR
                     GMNGEGQPWRVAIQKPTDKENAVQAVVDINGHGISTSGSYRNYYELDGKRLSHVIDPQ
                     TGRPIEHNLVSVTVIAPTALEADAWDTGLMVLGPDKAKEVVRREGLAVYMITKEGDSF
                     KTWMSPQFKSFLISEKN"
     gene            30790..31854
                     /gene="ada"
                     /locus_tag="IRB70_002877"
     CDS             30790..31854
                     /gene="ada"
                     /locus_tag="IRB70_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA-binding transcriptional
                     regulator/O6-methylguanine-DNA methyltransferase Ada"
                     /protein_id="HBC0632765.1"
                     /translation="MKNATCLTDDQRWQSVLARDPNADGEFVFAVRTTGIFCRPSCRA
                     RHALRENVSFYANASEALTAGFRPCKRCQPDKANAQQHRLDKITHACRLLEQETPVTL
                     EALADQVAMSPFHLHRLFKATTGMTPKAWQQAWRARRLRELLAKGESVTTSILNAGFP
                     DSSSYYRKADETLGMTAKQFRHGGENLAVRYALADCELGRCLVAESERGICAILLGDD
                     DATLISELQQMFPAADNAPADLMFQQHVREVIASLNQRDTPLTLPLDIRGTAFQQQVW
                     QALRTIPCGETVSYQQLANAIGKPKAVRAVASACAANKLAIVIPCHRVVRGDGTLSGY
                     RWGVSRKAQLLRREAENEER"
     gene            31854..32504
                     /gene="alkB"
                     /locus_tag="IRB70_002878"
     CDS             31854..32504
                     /gene="alkB"
                     /locus_tag="IRB70_002878"
                     /EC_number="1.14.11.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA oxidative demethylase AlkB"
                     /protein_id="HBC0632766.1"
                     /translation="MLDLFADAEPWQEPLAAGAVILRRFAFNAAEQLIRDINDVASQS
                     PFRQMVTPGGYTMSVAMTNCGHLGWTTHRQGYLYSPIDPQTNKPWPAMPQSFHDLCQR
                     AATAAGYPDFQPDACLINRYVPGAKLSLHQDKDEPDLRAPIVSVSLGLPAIFQFGGLK
                     RNDPLKRLLLEHGDVVVWGGESRLFYHGIQPLKVGGHPLTTDCRYNLTFRQAGKKE"
     gene            32580..34223
                     /gene="yojI"
                     /locus_tag="IRB70_002879"
     CDS             32580..34223
                     /gene="yojI"
                     /locus_tag="IRB70_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="microcin J25 efflux ABC transporter YojI"
                     /protein_id="HBC0632767.1"
                     /translation="MELLVLVWRQYRWPFISVMALSLASAALGIGLIAFINQRLIETA
                     DTSLLVLPEFLGLLLLLMAVTLGSQLALTTLGHHFVYRLRSEFIKRILDTHVERIEQL
                     GSASLLAGLTSDVRNITIAFVRLPELVQGIILTIGSAAYLWMLSGKMLLVTAIWMAVT
                     IWGGFVLVARVYKHMATLRETEDKLYTDFQTVLEGRKELTLNRERAEYVFNNLYIPDA
                     QEYRHHIIRADTFHLSAVNWSNIMMLGAIGLVFWMANSLGWADTNVAATYSLTLLFLR
                     TPLLSAVGALPTLLTAQVAFNKLNKFALAPFKAEFPRPQAFPNWQTLELRNVTFAYQD
                     NAFSVGPINLTIKRGELLFLIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVSGEQP
                     EDYRKLFSAVFTDVWLFDQLLGPEGQPANPQLVEKWLAQLKMAHKLELSNGRIVNLKL
                     SKGQKKRVALLLALAEERDIILLDEWAADQDPHFRREFYQVLLPLMQEMGKTIFAISH
                     DDHYFIHADRLLEMRNGQLSELTGEERDAASRDAVARTA"
BASE COUNT         8308 a         8492 c         9212 g         8279 t
ORIGIN      
        1 gccaaagttg gtggatattt taataaccta cgtgcggcaa atcaggcatt tgtgatggag
       61 cgacgcgatc acgctggtgg cgatggtcag acgctgaatt tacgcgttat cggcgggcgt
      121 tatcattaca cggcggcagg gcagttggct cagcatgaag acacttctac ggtgcagctt
      181 agcggcaacc tgtttagcgg gcactggggt gatgatggcg agtggatgct tgggattgtt
      241 ggtggctaca gcgataacca gggcgacagc cgctcgaata tgagcggaac tcgcgccgat
      301 aaccagaacc acggttatgc cgttgggctg acctcaagct ggtatcagca cggtaatcag
      361 aagcaggggg tctggctgga tagctggctg caatatgcgt ggtttaacaa tgatgtttct
      421 gaacaagacg atggcgtgga tcgttaccat tcgtcgggga ttatcgcctc gctggaagcc
      481 gggtatcagt ggttaccggg gcatggtgtg gtgattgaac cgcaggcgca ggtgatttat
      541 cagggcgtgc agcaggatga ttttaccgcc gctaaccatg cgcgcgtgtc acaatcgcag
      601 ggtgatgata ttcagacgcg gctgggttta cacagcgaat ggcgtaccgc tgttcatgtc
      661 ataccaacat tagatctgaa ttattatcac gatccccatg cgacggaaat tgaagaagat
      721 ggcagcacta tcagtgacga tggggtgaag caacggggtg aaataaaagt gggagtcacg
      781 ggcaatatca gtcagcgagt gtccctgcgc ggcagcgtgg cgtggcagaa agggagtgat
      841 gattttgccc agacggcagg gtttttgtcg atgacggtga aatggtaatc gctgtctgac
      901 catcactatt gccggatgcg gcgtaaacgc cttatctggc ctacggagag catttgtagg
      961 cctgataaga cgcggcaagc gtcgcatcag gcattggcgc ggttgccgga tgaatccaaa
     1021 caacaacctc acttattctg cgtgtgcagc atatagttca catccacgcc ggggccgagc
     1081 ttaaaggaat tagtgatcgg gttgtaatgt aacccggtta tatgtcgctc tttaagactg
     1141 gtctgatcca cccagcccag cagctctgcc ggtttaataa acttcttcac atcatgcgtg
     1201 cctttgggca ccatgcgcaa aatatattcc gcgccaacca ccgccatcag ccatgacttg
     1261 ccgttgcggt taagcgtcga gaaaaagaca tcgccgcccg gtttcaccag ttgcgcacag
     1321 gctctgacca ctgactgcgg atcggggacg tgctccagca tctccatgca ggtcaccaca
     1381 tcatactgcc cggcatgttt tgccgcgtgc tcttccacgg tttcctgcac gtaatccacc
     1441 tgaatgccgc tttccagcgc gtgcagcttt gccacctgca atggctcaaa gcccatatcc
     1501 agaccggtca ccgtcgcacc ttcgcgcgcc atactctcgg ccagaatgcc gccgccacaa
     1561 ccgacatcga gcaccttttt gccaaataaa ccgccagcac gctcggcaat atagcccaga
     1621 cgcagcgggt taatgcggtg cagcggtttg aactcacctt caagatccca ccagcgggag
     1681 gcgacagctt caaatttagc gatctcttcg tggtctacgt tatggtttac cggcgatttt
     1741 tcggcattca ttggcacttc tactccgtaa ttggcaagac aaacgagtat atcaggcatt
     1801 ggatgtgaat aaagcgtata ggtttacctc aaactgcgcg gctgtgttat aatttgcgac
     1861 ctttgaatcc gggatacagt agagggatag cggttagatg agcgaccttg cgagagaaat
     1921 tacaccggtc aacattgagg aagagctgaa gagctcctat ctggattatg cgatgtcggt
     1981 cattgttggc cgtgcgctgc cagatgtccg agatggcctg aagccggtac accgtcgcgt
     2041 actttacgcc atgaacgtac taggcaatga ctggaacaaa gcctataaaa aatctgcccg
     2101 tgtcgttggt gacgtaatcg gtaaatacca tccccatggt gacttggcgg tttataacac
     2161 gatcgtccgt atggcgcagc cattctcgct gcgttacatg ctggtagacg gtcagggtaa
     2221 cttcggttcc atcgacggcg actctgcggc ggcaatgcgt tatacggaaa tccgtctggc
     2281 gaaaattgcc catgaactga tggctgatct cgaaaaagag acggtcgatt tcgttgataa
     2341 ctatgacggt acggaaaaaa ttccggacgt catgccaacc aaaattccta acctgctggt
     2401 gaacggttct tccggtatcg ccgtaggtat ggcaaccaac atcccgccgc acaacctgac
     2461 ggaagtcatc aacggttgtc tggcgtatat cgatgatgaa gacatcagca ttgaagggct
     2521 gatggaacac atcccggggc cggacttccc gacggcggca atcattaacg gtcgtcgcgg
     2581 tattgaagaa gcttaccgta ccggtcgcgg caaggtatat atccgcgccc gtgccgaagt
     2641 agaagttgac gccaaaaccg gacgtgaaac cattatcgtc cacgaaattc cgtatcaggt
     2701 aaacaaagcg cgcctgatcg agaagattgc ggaactggta aaagaaaaac gcgtggaagg
     2761 catcagcgcg ctgcgtgacg agtctgacaa agacggtatg cgcatcgtga ttgaagtgaa
     2821 acgcgatgcg gtcggtgaag ttgtgctcaa caacctctac tcccagaccc agttgcaggt
     2881 ttctttcggt atcaacatgg tggcattgca ccatggtcag ccgaagatca tgaacctgaa
     2941 agacatcatc gcggcgtttg ttcgtcaccg ccgtgaagta gtgacccgtc gtactatttt
     3001 cgaactgcgt aaagctcgcg atcgtgctca tatccttgaa gcattagccg tggcgctggc
     3061 gaacatcgac ccgatcatcg aactgatccg tcatgcgccg acgcctgcag aagcgaaaac
     3121 cgcgctggtt gcaaatccgt ggcagctggg caacgttgct gcgatgctgg aacgtgcggg
     3181 cgacgatgct gcgcgcccgg aatggctgga gccagagttc ggcgtgcgtg atggtctgta
     3241 ctacctgacc gaacagcaag ctcaggcgat tctggatctg cgtctgcaga aactgaccgg
     3301 ccttgagcac gaaaaactgc tcgacgaata caaagagctg ctggatcaga ttgcggaact
     3361 gttgcgtatt cttggtagcg ccgatcgtct gatggaagtg atccgtgaag aactggagtt
     3421 ggttcgtgaa cagttcggtg acaaacgtcg taccgaaatc accgctaaca gcgccgacat
     3481 caacctggaa gatctgatca cccaggaaga tgtggtggtc acgctttctc accagggtta
     3541 cgtgaagtat cagccgcttt ctgaatatga agcgcagcgt cgtggcggga aaggtaaatc
     3601 tgccgcacgt attaaagaag aagactttat cgaccgactg ctggtggcga acactcacga
     3661 ccatattctg tgcttctcca gccgtggccg cgtctattcg atgaaggtct accagttacc
     3721 agaagctact cgtggcgcgc gtggtcgtcc gatcgtcaac ctgctgccgc tggaacagga
     3781 cgaacgtatc accgcgatcc tgccggtgac cgagtttgaa gaaggcgtga aagtcttcat
     3841 ggcgaccgct aacggtactg tgaagaaaac cgtcctcacc gagttcaacc gtctgcgtac
     3901 cgccggtaaa gtggcgatca aactggttga aggcgatgag ctgatcggcg ttgacctgac
     3961 cagcggcgaa gacgaagtaa tgctgttctc cgctgaaggt aaagtggtgc gctttaaaga
     4021 gtcttctgtc cgtgcgatgg gctgcaacac caccggtgtt cgtggtattc gtttaggcga
     4081 aggcgataaa gtcgtctctc tgatcgtgcc tcgtggcgat ggcgcaatcc tcaccgcaac
     4141 gcagaacggt tatggtaaac gtaccgcagt ggcggaatac ccaaccaagt cgcgtgcgac
     4201 gaaaggggtt atctccatca aggttaccga acgtaacggt ttagtggttg gcgcggtgca
     4261 ggtagatgac tgcgaccaga tcatgatgat caccgatgcc ggtacgctgg tacgtactcg
     4321 cgtttcggaa atcagcatcg taggccgtaa cacccagggc gtaatcctta tccgtacttc
     4381 ggaagatgaa aacgtggtgg gtctgcaacg tgttgctgaa ccggttgacg aggaagatct
     4441 ggataccatc gacggcagtg ccgcggaagg ggacgatgaa atcgctccgg aagtggacgt
     4501 tgacgacgag ccagaagaag aataatttca tcgcttcatg ccaaaaggga gccatctccc
     4561 ttttttgaat tgaaaagtcc aggctgtaaa gtctgggctt ttgtcgtatt agggcgcggt
     4621 aaagtttggc tgtgcccgta aaaaatggct ggctatacac aaggaatgtg gcaatgagtg
     4681 gtgaaaaaaa ggcgaaaggc tggcggtttt atggccttgt tggttttggg gcaatagcgc
     4741 tgctatccgc tggcgtatgg gcattacaat actctggcag tgggccagaa aaaacgttgt
     4801 cgccactggt ggtgcacaac aatctgcaaa tcgatctcaa tgagccggac ctctttctcg
     4861 acagcgactc tctgagccag cttcccaacg atctccttac cattccgttt ctccacgatg
     4921 ttctgagcga agatttcgtt ttctattatc agaatcatgc cgatcgtctg ggcattgaag
     4981 gcagcattcg ccgcattgtc tatgaacacg atctcacgct gaaagataag ctcttttcgt
     5041 cactcttaga ccagcccgcg caggcggcac tgtggcacga taaacaaggc catctttctc
     5101 attatatggt gctgatccag cgtagtggtt taagcaaact gctggagcca ttgctgtttg
     5161 ccgccaccag cgacagccag ttaagcaaga cggaaattag tagcatcaag ataaatagtg
     5221 aaactattcc tgtttatcag ttgcgctata acggcaataa cgtcctgatg tttgcgactt
     5281 atcaggacaa aatattggcg ttttccagtt cggatatgct gtttaaagat gaccaacagg
     5341 ataccgaagc cacggcgatc gcaagtgatt tgttgagcgg taaaaaacgc tggcaagcca
     5401 gctttggcct ggaagagcgt gctgctgaaa aaacgccagt acgccagcgt attgttgtca
     5461 gcgccaggtt gctggggttt ggctaccagc gattaatgcc ttcttttgct ggcgtacgct
     5521 tcgaaatgag caacgacagc tggcatagct ttgtggcgtt aaatgatgaa tccgccagcg
     5581 tagatgccag tttcgatttt acgccggtat ggaacagtat gcctgccggg gccagcttct
     5641 gtgtggcggt gccgtattcg catggtattg ccgaagagat gctttcgcac atcagccagg
     5701 aaaacgacaa gctgaacggg gcgttagatg gtgcagccgg gctgtgctgg tatgaagact
     5761 caaaattaca aaccccgcta tttgttggtc aatttgatgg ctcagccgaa caggcacaac
     5821 tgcctgggaa actgtttacg caaaatattg gtgcgcacga aagcaaagcg ccagaaggtg
     5881 ttttgccggt aaaccagacg cagcagggcg aagcgcaaat ctggcgtcgc gaagtgagtt
     5941 cccgatacgg ccagtatccg aaagcgcagg cggcgcaacc cgatcaatta atgtcggatt
     6001 attttttccg cgtgtcgctg gcgatgcaaa acaaaacgct gcttttctcc ctcgatgaca
     6061 cgctggttaa taacgcgctg caaacactga ataaaacccg cccggcaatg gtggatgtga
     6121 tacccactga cggcatcgtt ccgctctata tcaatccaca aggcgtggcg aaactgctgc
     6181 gtaacgaaac gctgaccagt ttgccgaaga atctcgaacc ggttttttat aatgccgcac
     6241 aaactttatt aatgccgaag ctggacgctt tatctcaaca accgcgttat gtcatgaagc
     6301 tggcacagat ggaacccggt gccgcctggc agtggctacc cataacctgg cagccgctat
     6361 gaggcacgga ctgctggcgc tgatttgctg gctgtgttgt gttgttgccc atagcgaaat
     6421 gctgaatgtc gaacaatccg ggctgtttcg cgcgtggttt gtacgcattg cacaggaaca
     6481 gctccgccag gggccaagtc cgcgctggta tcagcaggat tgtgcgggcc tggtgcgatt
     6541 ttcggcgaac gaggcgctga aaattcacga cagcaaatgg ctaaaaagta acggtatagc
     6601 aagtcaatat ttgccgcctg aaatgacgct aacacctgaa cagcgtcaac tggcgcaaaa
     6661 ctggaatcag gggaacggaa aaactggccc ctatgtgacc gcgattaatt tgattcagta
     6721 caacagccaa tttattggcc aggacataaa ccaggcgctg cctggcgata tgattttttt
     6781 cgatcagggc gatgcccagc acttaatggt ttggatgggg cgttacgtca tctaccacac
     6841 cggaagcgcc acgaaaactg acaacggaat gcgcgcagtc agtctgcaac aacttatgac
     6901 atggaaggac acccgatgga tacccaacga ttccaatccc aatttcattg gcatttatcg
     6961 tttaaatttt ctggcgcgat agcagcgtgc ttttgcctgt ctcttgtggg aacagggctt
     7021 gctaatgctg atgattcgct tctttccagt aactatgcgc cgcccgccgg gggaacattc
     7081 tttttgctcg ctgacagcag ttttagcagc agtgaagagg cgaaagtgcg actggaagcg
     7141 ccggggcgtg attatcgacg ctatcagatg gaagagtacg gtggcgtgga cgttcgcctg
     7201 tatcgtattc ctgacccgat ggcatttttg cgccagcaga aaaacctgca tcgcattgtg
     7261 gtgcaaccgc aatatctggg cgacgggcta aacaatacgc tgacctggct gtgggataac
     7321 tggtacggca aatctcgccg tgtaatgcag cgtactttct cttctcagtc acggcagaat
     7381 gtgactcagg cgttacccga attacagctc ggtaatgcca ttgttaaacc ttcccgttat
     7441 gtacagaaca gccagttttc accgctgaaa aaatatccac tggtggaaca attccgttac
     7501 ccattatggc aggctaaacc ggtcgagccg cagcaagggg taaaactgga aggcgcatcc
     7561 aacaatttca tctcgccgca gccgggtaac atttatattc ctctcggcaa acaagagccg
     7621 ggattgtacc tcgtcgaggc gatgataggt gggtatcggg cgacgacggt ggtgtttgtt
     7681 tccgataccg tggcgcttag caaagtgtca ggtaacgagc ttctggtgtg gaccgcaggt
     7741 aaaatacagg gtgaagcgaa gccgggatca gagatcctgt ggactgacgg tcttggcgtg
     7801 atgacacgcg gggtgaccga tgacagcggt accttgcagt tacaacatat atcgccggaa
     7861 cgctcataca ttctgggtaa agatgcggaa ggcggcgttt ttgtctccga gaacttcttc
     7921 tacgaaagtg aaatctacaa cacccgcttg tatatcttta ccgatcgccc gctatatcgc
     7981 gcaggcgatc gtgtcgatgt taaagtgatg ggccgcgagt tccacgatcc gttgcattca
     8041 tcccccatcg tcagcgcccc ggcgaagctt tcagtgctgg acgctaacgg cagtctgttg
     8101 caaaccatca atgtcacgct ggatgcgcgc aatggcgggc aggggagttt ccgcctgcca
     8161 gaaaatgccg ttgccggagg ttatgagtta cgtcttgctt accgcaatca ggtctatagc
     8221 agtagttttc gcgtggcaaa ctacatcaag ccacatttcg agattggctt agctctcgac
     8281 aaaaaagagt tcaaaactgg cgaagcggtc agcggcaaac tgcaactgct ctacccggat
     8341 ggtgagccgg taaaagatgc ccgtgtgcag ttaagtttgc gcgctcagca attatcaatg
     8401 gtcggtaacg atttgcgtta tgccggacgt tttcccgtgt cgctggaagg cagtgaaacg
     8461 gtatccgacg atagcggtta tgtggcgtta aatctccccg ccgctgataa accaagccgc
     8521 tatttgttaa ccgtctccgc cagtgacggt gcggcgtatc gtgtcaccac caccaaagag
     8581 atcctcattg aacgtggact ggcacattac tcattaagta ctgccgcaca atacagtaat
     8641 agcggtgaat cggttgtgtt ccgttatgcc gcgctggaat cttcaaaaca ggttcctgtt
     8701 acgtatgaat ggttgcgtct cgaagaccgc acgagccata gcggagagct accgtcaggc
     8761 ggcaaatcct ttaccgtcaa tttcgctaaa cctggcaact acaatctgac attacgcgat
     8821 aaagacggct taattctcgc tgggttaagt catgccgtca gcggtaaggg cagcacggcg
     8881 catactggta cggtagatat cgtggcggat aaaacgctgt accagccagg cgaaactgcg
     8941 aagatgctga ttacctttcc ggagccaatt gatgaagcat tattgacgct ggaacgcgat
     9001 cgcgtggaac agtagtcgct gctttcgcat ccggcaaact ggctgacgtt acaacgttta
     9061 aacgataccc agtatgaagc ccgggttcca gtgagcaatt cctttgcgcc taacatcact
     9121 ttttcggtgc tgtatacccg taacggtcag tacagttttc agaacgccgg gatcaaagtt
     9181 gccgttcccc agctggatat ccgggtgaaa acggacaaaa cccattacca gcctggtgaa
     9241 ctggtcaatg tcgaattaac ctcgtcgctg aaaggtaaac ctgtttctgc gcagttaacg
     9301 gtaggcgtgg tcgatgaaat gatctacgcg ctgcaaccgg aaatcgcgcc gaatatcggc
     9361 aaatttttct atccgctggg gcgtaacaat gtgcgtacca gctccagttt gtcgtttatc
     9421 agctacgacc aggcgctctc cagcgagccg gttgcgcctg gcgcaactaa ccgcagcgag
     9481 cggcgagtaa aaatgcttga acgtccacgg cgtgaagagg tggataccgc ggcatggatg
     9541 ccgtcactca caaccgataa acaaggcaaa gcgtatttca cgttcctgat gcctgattcg
     9601 ttaacccgct ggcgtatcac cgcgcgtggg atgaacggcg acgggctggt cgggcagggg
     9661 cgtgcttatc tgcgttcgga aaaaaatctc tacatgaagt ggagtatgcc aacggtgtat
     9721 cgcgtgggcg acaaaccggc ggcaggactg tttatcttca gtcagcagga taacgaaccg
     9781 gtggtgctgg tgactaaatt tgcaggcgct gagatgcgcc agacgctgac gctgcacaaa
     9841 ggggcgaatt atatttcgct gacgcagaat attcagcaat ctggcttgtt aagtgcagaa
     9901 ctgcaacaaa atgggcaagt gcaggacagc attagcacaa aactgtcttt tgtggacaac
     9961 agctggcccg ttgaacagca gaaaaatgtc atgctcggcg gtggcgagaa cgcgctgatg
    10021 ttgcccgagc aggcgagcaa tatccggctt caaagtagtg aaacgccgca ggagattttc
    10081 cgcaacaatc ttgatgcgtt agtcgatgaa ccgtggggtg gggtgatcaa caccggtagc
    10141 cgtctgatcc cgctcagtct cgcctggcgt tcgcttgccg atcatcaaag tgccgccgct
    10201 aacgacattc gtcagatgat tcaggataac cgtctgcggc tgatgcaact ggcggggccc
    10261 ggagcgcgct ttacctggtg gggtgaagat ggcaatggcg acgccttcct gacggcatgg
    10321 gcatggtacg ccgactggca ggccagccag gcgctcggcg taacgcaaca accggaatac
    10381 tggaaacata tgctcgacag ttatgccgag caggcggata acatgccgtt attgcatcgg
    10441 gcgctggtgc tggcatgggc gcaggagatg aatctgccgt gcaaaacgtt gttgaaaggg
    10501 ttggatgaag ctatcgcccg gcgcggaact aaaactgaag atttctctga ggcagacacc
    10561 cgcgatatca atgacagcct gatcctcgat acacctgaat ctccactggc agatgcggtg
    10621 gcaaacgtct taaccatgac gttgctgaaa aaagcgcagt tgaagtccac ggtgatgcca
    10681 caggttcaac aatatgcgtg ggataaagcg gcaaacagca atcagccgct ggcgcacacg
    10741 gttgtgctgc tcaatagcgg gggcgacgct acccaggcgg ctgctatttt aagtggtttg
    10801 accgctgagc aatctactat tgagcgcgcg ctggccatga actggctggc gaaatatatg
    10861 gcgacaatgc ctccagttgt tttgcctgcg cctgcgggcg catgggccaa acataagtta
    10921 actggagggg gcgaatactg gcgttgggtt ggtcagggcg tgccggacat tctctctttt
    10981 ggtgacgaat tatcgccgca aaatgtgcag gtccgctggc gtgaaccggc aaaaacggct
    11041 caacaaagta acattccggt gaccgttgaa cgccagttgt atcggcttat ccccggtgaa
    11101 gaagagatga gctttactct gcagccggtg accagcaatg agattgacag cgatgcgctg
    11161 tatctcgatg aaatcacgct taccagcgag caggatgcag ttctgcgcta tggtcaggtg
    11221 gaagtaccgc tcccgccggg agccgatgtt gagcgcacaa catggggcat ttcggtcaat
    11281 aaacccaacg ccgcgaaaca gcaggggcaa ttgctggaaa aagcgcgcaa tgaaatgggc
    11341 gaactggcct atatggtgcc ggtgaaagaa ctgacgggaa cggtcacttt ccgccatttg
    11401 ctgcgcttct cgcaaaaagg gcaattcgtt ctgcctcctg ctcgttatgt gcgttcctat
    11461 gcacctgcac agcaaagtgt tgcggcaggg agcgaatgga ccgggatgca ggtgaaataa
    11521 gtgaactggc gcagaatcgt ctggctatta gcgttggtta ctctgccaac gcttgcggag
    11581 gagacgtcgt tacaactggc gctgcggggc gcgcagcatg accaactgta tcagttatcg
    11641 tcgtcaggcg tgaccaaagt ctcggcatta cctgacacgc tcaccacgcc gttagggagt
    11701 ttatggaaac tgtatgttta cgcctggctg gaggataccc atcaaccgga gcagccctac
    11761 cagtgtcgcg gaaactcccc ggaagaggtt tattgttgtc aggcagggga gagcataacg
    11821 cgcgataccg cgctggtacg ttcctgtggg ctctattttg cgccgcagcg gttgcatatt
    11881 ggcgcagatg tgtgggggca atactggcaa cagcgtcagg cacctgcgtg gttagcgtct
    11941 cttactacgc tgaagccaga aacctcggta acggttaaat cactgcttga ttcattagcg
    12001 acgttacccg cgcaaaacaa agctcaggaa gtcttactgg atgtggtgct ggacgaggcg
    12061 aaaatcggtg tcgcatctat gctcggtagt cgggtacggg tgaaaacctg gagctggttt
    12121 gccgataata aacaggaaat ccgtcagggt ggttttgccg gctggttaac cgatggtaca
    12181 ccgctatggg tgactggcag tggcaccagc aaaacggtac tgacccgtta tgcgacggtg
    12241 cttaatcggg ttttgccagt gccgacgcag gttgccagtg ggcaatgtgt agaggtggag
    12301 ctgtttgccc gctatccgct gaagaaaatc gcagcggaaa agagtacgac ggcagtaaaa
    12361 cccggcgtac ttaatgggcg ctatcgtgtg acgttcgcca atggtaacca cattacgttt
    12421 gtcagccacg gtgagacgac cttactgagc gaaaagggca aactgaaatt gcagtcgcat
    12481 ctcgatcgtg aagagtatgt tgccagagtt ctggatcgcg aggcgaaaag tacgccccct
    12541 gaggcagcga aagccatgac cgtggcgata cgcacttttt tacagcaaaa cgccaatcgg
    12601 gaaggcgatt gcctgaccat ccctgacagc agcgccacac agcgtgtttc ggcttcgcca
    12661 gctaccacgg gggcgcgaac gatgaccgcc tggacgcagg atcttatcta tgcgggcgat
    12721 ccggttcatt atcacggcag tcgcgctacc gaagggacgc tttcctggcg gcaagccacg
    12781 gcccaggcgg ggcagggaga gcgttacgac cagatactcg cgtttgctta tcccgacaac
    12841 agccttagcc gctggggagc gccacgctca acctgccagt tattacccaa agcgaaagcc
    12901 tggctggcga aaaaaatgcc gcagtggcgg cgtatattac aaggcgagat ggggtacaac
    12961 gaaccagacg tgtttgcggt ctgtcgttta atctcaggtt tcccctatac cgatcggcag
    13021 cagaaacggc tgtttattcg taacttcttt acgcttcagg atcggctcga tttaacccat
    13081 gagtatctgc acctggcctt tgatggttat cccaccgggc ttgatgagaa ctatatcgaa
    13141 acgctgaccc gacaattatt aatggactaa tgctatgcga aagatttttc ttccgttgtt
    13201 actggtggcg ctttcgcctg tcgctcacag tgaaggtgtg caggaagtcg agattgatgc
    13261 accgctctct ggctggcatc cggcagaggg cgaagatgcc agtttttcac aatcgatcaa
    13321 ttacccggcg tcgtccgtca acatggcaga tgatcaaaat atctcagcgc agatccgcgg
    13381 caaaataaag aattatgctg cggcgggtaa agttcagcag ggccggctgg tggtcaacgg
    13441 tgccagtatg ccgcagagaa ttgaatccga tggttcattt gcacgccctt atattttcac
    13501 ggaaggcagc aacagcgtgc aggtcatcag cccggatggg caaagccggc aaaaaatgca
    13561 gttttactca acgccgggtg ctggagtgat ccgcgcgcgt ttacgactgg ttctctcgtg
    13621 ggatacggac gataccgacc tcgaccttca cgttgttacg cccgatggcg aacacgcttg
    13681 gtacggtaac accgtgctga acaacagtgg tgcactggat atggatgtca cgacggggta
    13741 cggccccgag attttcgcca tgccagcgcc agttcacggg cgctatcagg tgtatatcaa
    13801 ctactatggc ggacgcagcg aaacggaatt aaccaccgcc caactgacgc tgatcaccga
    13861 tgaaggatcg gtcaatgaga aacaggaaac atttattgta ccgatgcgta atgctggcga
    13921 gctgacgctg gtgaaaagtt ttgactggtg attaatgggg ttaccttcgc cgtcgatgtt
    13981 caagaaaacg cccgataact ttcgctatcg ggtgttttta ttggttaatt caaccgttca
    14041 atcaccatcg caattccctg gccgccacca atgcacagtg ttgccagccc cagcgtttta
    14101 tcgcgtgcct gcatggcatg taatagtgtg accagaatac gagcaccact ggcaccgata
    14161 ggatgcccga gcgcgatggc cccgccgttg acattcactt tctcagaatc aaagcccagg
    14221 gttttcccaa cggcaaggaa ctgtgcggca aatgcttcat tagcctcaat gagatcaata
    14281 tccgccagtt gcagccccgc cagttgtaac gctttttgcg tggcaggtac tggtcccata
    14341 cccatcaatg cggggggcac gccaccgctg gcataacttt taatgcgagc caggggggta
    14401 aggcctgctg ccagcgccgc agattcttcc ataatcacca gagcggcagc accgtcgtta
    14461 ataccagacg cgttcccggc ggtgactgtt cctgctttat cgaaggccgg acgcaatgcg
    14521 cctaacgctt cagtcgtaga atccgctttc gggaattcgt cttgactgaa gacgaaggtt
    14581 ttcttccggg tgacaacatt taccgggacg atttcggctg taaaagcacc ggactcaatt
    14641 gcggctgccg ctttacgctg tgaatgtagc gccagttcat cctgcatttc tcgggtaatt
    14701 ccgtactctt tggccacgtt ctcggcggta atccccatat gataaccatg ggtggcgcac
    14761 atcagaccat cgcgcaggat tacgtcataa acctgtccgt ctccaagacg ataaccagag
    14821 cgtgcttttg catcgagtaa gtagggcgct aaactcatat tttccatacc ccccgccaca
    14881 atgctttgcg cctgacctgc ctgaattgcc tgggcggcaa gcgccacact tttaagaccc
    14941 gaaccacaca ctttattgac cgtgaatccg cacaccgttt ctgccagccc gctttttaac
    15001 agtgcctgac gcgccggatt ttgccccagc ccggcttgca acacgttacc cataatcact
    15061 tcatcaatgt gtagtgaatc gatttttgca cgttcaatgg cggctttaat tactgtcgcc
    15121 cccaggtcga tggcgctggt ggaagcgagt gaaccgttaa aactaccgat agcagtacgt
    15181 accgcactga cgatgacaca atttttcatt ttatattcct tctgtctgta gggttgccgt
    15241 cagaacagcg ttaaaccaat gacgaaaatg acgccggaga agagcagggc agtgatgcaa
    15301 tagcccatga tgtcgcggac accgagtccg gcgattgcca gtgctggcag cgcccagaac
    15361 ggttgtgcca tgttcatcca ttgctcgccg taggcgatcg ccattaccga tttaccgaga
    15421 tcagcgccca gcgcctgggc tgcgggcatc acgaacggcc cctgaataac ccagtgcccg
    15481 ccgccagacg gaacggcgaa gttaatcagt gcagaactaa aaaaggtcat gaccgggaag
    15541 gtgtctttgt tcgcaacatt aatgaagaat tcggtaatga gtccgcccag accggagtgc
    15601 tccatcatca gttggatccc cgcgtagaag gggaattgca ccagaatacc ggcggtactg
    15661 cgtgctgccg cgctgatagc acgcatataa gccattggcg ttttatgtag cagcagaccc
    15721 gcaatcataa acatcaggtt gacggtattg atggtgatgt tgaagccatg ttcgctgaag
    15781 tacatcgcca ggtaagcgat accgagtgcg ccgatgatca acgtcagaat acggctttct
    15841 tccagtcgct cggacggtgg agcatttttc ggtagttgct tttgaaaatc agcctcttcc
    15901 atgagtagtt tcggatcgat actcaccacg tcagacggtt ttggcatcat catgcgggtg
    15961 ataaatggca tcaccacaat caacgccaca gtgatgaaaa tattaaaacc actgaacaga
    16021 gtatcgccca ccgggatcag cccggcgata tgctcaaccg ggttgcccgg tgttgcagcc
    16081 aacagaggca ttgagccaga gaaaccgcca ccccaggtga gaaaaccaat gtaggcgcag
    16141 gcaatgagca acggataatc agaaccgggt actcggcggg cgacttcacg ggcaaacatt
    16201 gcgccgacaa ccaaaccaaa tccccagttg atgacacaag cgactgaacc gaagaaagta
    16261 accagcatga cgccctgtac gggcgtcttt gcggcggagg cggcagtacg cagcaaactt
    16321 tttaccggag cagagctggc aagggcatga ccggtaacga tgataagcgc catctgcata
    16381 ccaaacgcca gcaagttcca gaaaccgtca ccccacattt tcaccatgct gatcggcgtt
    16441 tgtggtgtta accaaagcgc gatcacgaat gttagcaatg tcagcaacat ggcaaagatc
    16501 agtggatcgg gaagccaccg gctgacaaaa cgcgtcataa aacgcgatat gcgaccaatc
    16561 ataaatcacc ccgttgcgta ttcaggtcgg cagctacttc aaaccgagct tctgttttgg
    16621 cacgcacggt ggctaaatca cacccgtcgg caatttcggt gagccacatt ttgccgtcaa
    16681 taaaacgaaa gacagccagt tcagtaacca gcatatgcac cgcatgttgc gcagtgagag
    16741 gcatggtgca gcggcgcaaa atttttgctg aaccatcttt ggcgcaatgt tccatggcga
    16801 tgatcacttt gcgcgacccg gtcaccagat ccatcgcgcc acccataccg ggcaccattt
    16861 tcccaggcac tacccagttc gcgaggtttg cttcttcgtc tacttgcaaa ccgccgagca
    16921 cgcaggcatc aatatgaccg ccacggatta gcgcaaatga catggcgcta tcaaacatgg
    16981 ctgcaccggg taaaacaccg cacggttgtc cgccagcgtt caccagatct ggatgcgctg
    17041 tcgtgaccgg gcctaaaccg aggaagccgt tttccgattg cagagtgata tgaataccct
    17101 ccggtaaata attggcgacc attgtgggta aaccgatccc taagttaacg atgtcaccat
    17161 cacgaagctc ttgcgccaca cggcgcgcaa tacgttgttt cgcatccatt atttgctctc
    17221 ctgtgaaacg atgatgtggt cgataacggc accaggggtg acaatatggt caggttgcag
    17281 ctcgccggtt tcgaccagtt catctggctc taccagcgtg atatcagccg caagggctat
    17341 cagggggtta aagttgcggg cgctaaggtg ataggtcagg ttgccaagtg tgtcgcaacg
    17401 atgagcgcga attagcgcca ggtcggcgcg cagcgggcgt tcgagcagcc aggttttacc
    17461 gtcgagtgtc agtgtctgtt tgccttcctc tacgacggtg ccgacaccag ttggggtgag
    17521 aaaaccacca agtccagctc cgccacagcg aatttgctcg attagcgtac cttgcggtac
    17581 cagaacgacg tccatctcac cagaaatcat gcgccgacct gtttccgggt tggtaccgat
    17641 atgtgaagca atcactttgc ggactcgacc attgacgatg agcggaccga tgccggtatc
    17701 aacaaacgcg gtatcattgg ctatcaatgt caggtcgcga acaccagatt ccagtaatgc
    17761 ttcaaccagg cgggatggag tgccaatccc cataaatccg cccaccatga tggtcatgcc
    17821 gtcacgaaag aagccggtgg cgtcttgtaa tgtcatcaat tttgttttca ttttttatcc
    17881 ctcttgcata caccgttgtg ggtacagtca gggaatagca aggggagtgc cagaatgaga
    17941 ttattggggg ttgttattta actaattgaa tagaaaagga taaattagat gggggtttat
    18001 aaggaaaatg agcggctatg cagaaaattg cgcactgtgc aaatttctgc atagcaagtt
    18061 ttggcgttat acatccgccg gatcgatacc gtattcctgg agtttataca tcaatgcacg
    18121 gcgactgatg cccagcatta aagcagtgcg ggttcggttt ccttcttgtt gttccagcac
    18181 ttccataatg atgcgttttt cgacgcgttt aatttcctct tttaaattac gctcaccgac
    18241 aggggctgtt tttgcttcac cagcattaca gactggctga cgaatctgcg gcggaagatc
    18301 ctcagaaaaa atgatcgggc ctgaattcat cacgacggcg cgttcaataa cgttggaaag
    18361 ctctcgaata tttcccggcc atgaccaggc ggtaagcagt gacattgcca tcggatcgat
    18421 gtcgataata tcgcgctgat tctcactact gaatttttgc aaaaagtgat tagctaacag
    18481 ggaaatatct tcccggcgat cgcgcagagg cggcagtatt aaatgaataa cgttaaggcg
    18541 ataaaagaga tcttcacgga aggtgccttc tttcaccatt gcctgcaagt cgcggttggt
    18601 ggcagcaatg atgcggatat caacttttat ggtctgatgg ccgccaatcc gttcaaattc
    18661 ccgttcctgc agaatgcgta gtaatttggc ttgcagtacc agcggcattt caccaatttc
    18721 gtcgaggagc agagtacctt cgttggcacg ttcaaataat ccctgacgca aggtttgtgc
    18781 accagtaaat gcaccttttt catgaccaaa cagttcactt tcgagcaacg attccggcag
    18841 tgccgcgcag ttgactttaa tgaacggccc ctttgcccgc cgcgaattgt agtgaatcgc
    18901 tctggcaatc aactctttcc cggtgccgct ttcaccacta atcaagacgc tggcctgaga
    18961 aagggcaatt ttggcggtgt ctttgcagat gtccatcatc gccgggctgt tggtgagaat
    19021 gtgcccccat tgccagctgg tgctcagtgc ctggtgcaga tgacggatct cttttttcat
    19081 tgactggagt tgtaaagcgc gctgaacgat taaattcaac tcatcgagat caaacggttt
    19141 gataacatag tcgaaggctc cgcagcgtag tgcttcgacg gcggtttcca cttcagcata
    19201 ggccgtcatc agaataacgg gtgtccgggt ctcatggctg cgcatctcct tgagtgcctt
    19261 gatgccgtcc atctctggca tgcggatatc catcaacacc acgtcagggt gaatatcggc
    19321 aaacaggtgt aatgctgtgc gcccgttgtt cgcacaatgt gtttcgaatc cttgtagtgc
    19381 aaaagcggtg ctcagcatac ggcgaacatt atcttcatca tccacaataa ggatgcgatt
    19441 aatagcagtc atacagtctg atttccctgc gggttgatcg gtaaaataag cgtgaaggtt
    19501 gcgccgtagc ccggcaaact ggcgacgcga atatcaccct gatgggcatt aatgatgcgt
    19561 tgacttaacg ccagaccaag cccggttcct gaggctttgg tggtgaaaaa gggatcgaag
    19621 atcttttttt gcagcgagag atcaatgcca cagccgttgt cctctatcga aatggcctgt
    19681 tgtgagtcgc tgtattgcca ggttcgaatg cgaattttcc ctcgtgcact gatagcctgg
    19741 acggcattga tcaggatatt cagtagtacc tgtttgagca gttcacgatc ggcgttaatc
    19801 gggcttaatt cattatccag ttcgcttatg aagtcgaccc gcgcttgtac gccagcggtt
    19861 tgtaccagta ccagagtttc ttcaaccaat gcattgaggc tgacttgttg ccattgactg
    19921 tggcgtgggc gtgaaaattc gagcaattgc tgaataactt tgttaattga atcgatttct
    19981 ttgagtacta cggacagata ttcctgatgt attaggtcgc tggtttgttg gcgcaagatc
    20041 tgtacataac cacgaatagc cgttagcgga ttacgtactt catgcgcgac gccagccatc
    20101 agctcaccca gtgtggcgag gcgttctgct tgcgccatgc ggcgctgggt ttctttgcgg
    20161 gcagttaaat cagagaaaat caccaaagca cctatcattt caccgtgcgt gttatgaata
    20221 cgactggtag tgacactgag ttcaatggtg cggtcacggc ctggaaaact gatctccagc
    20281 gctacatgtt cggtgccatg ttccagcgta tccagtactg gactgtagaa ctgagtattg
    20341 tcgaacaaca tggagtaagg ctgccctacc agttcatggc gttgatagcc agtaataact
    20401 tctgctgctg ggttcatggt ggttacatca ccctggcggt caatggcaat gacgccatcg
    20461 gcagcgtttt caataatcag atcgttaagt gttcgcgttt cacgcagtgc ctgggcgagg
    20521 ttgttaacac tctgactgat ttgccccatt tcaccgggca attgtggtaa tcgagtggga
    20581 atattttgtg ccagagtcga gaggccatcg gtgatgatat caatattggc gctcaggcga
    20641 cgggagaaaa ggacaatcaa cagcaggctt atcagcaaac cggcggtaag cacaatgata
    20701 atcctcacat ccattttcca ggcctggcgg cgaatatctt cggttaattc attggcccag
    20761 atatagccga ggatttcacc attacgctca atggggatca ttgaattcaa aatatcgccg
    20821 cgcacctgcc tgcctgaata aaccaaaggg gtatttgtac gcatgacttc gcgaccaggg
    20881 tgatctgcgg caatggtaac gccgacatta ttctgatata gcgctgaagg cgcgtaggtg
    20941 attatcgcat ccagcgtttt gttgtaataa ccagcgccga tgccagggaa ggcgtgagtg
    21001 atattttcgg taatgggggc aagttctgca tttaatgcgc ggatacgctc ctcacgtggt
    21061 aagtcgatgt agagatcata gcgatcgcct agcgcctgat taagcaggtt gaccacggca
    21121 gatagttttt tctctttttc agataagact gctgaacgcc cttccgtttc tacgatataa
    21181 ccaatagtaa gcgttgggac aatgaccatc aggattgcca tcaggatcat ttgattgcgt
    21241 aagcggcgtg gataaatcca cttcatataa tgcatgctga aatccactag tcttgtccgg
    21301 tatatgacga ttatcagagg ttaaggtgat gatttctcgg cggtgtatca tattccagag
    21361 aagagagaac attgcggtaa cacgctttta ccgctacctt aaccacactc catcggtcac
    21421 ctgaggcgga gcttcgcccc tttgaaatac cttgcttctt ttcgtacaac cctgaaagcc
    21481 tcgcgctaca tgttcagagc attggcgtta gtgctctggc tgttgattgc tttttcatcc
    21541 gttttttaca tcgttaatgc gttgcatcag cgagaatcgg aaattcgtca ggaatttaat
    21601 ctgagttctg atcaggctca gcgctttatt caacgcacct ctgatgtgat gaaagagctg
    21661 aagtacatag ctgaaaatcg cttatcggca gaaaacggtg tgctttcccc gcgtggacga
    21721 gaaacgcagg cggatgtgcc tgcgtttgaa ccgctgtttg ccgactccga ttgttccgca
    21781 atgagtaaca cctggcgagg ttctctggag tcattggcgt ggtttatgcg ctactggcgc
    21841 gataattttt ctgcggctta cgatctcaac cgggtatttt taatcggcag cgataacctc
    21901 tgcatggcca atttcggtct gcgtgatatg ccagtggaac gcgataccgc gttgaaagcg
    21961 ttgcatgaac gcatcaataa atatcgaaat gcaccacaag atgatagcgg cagtaacctc
    22021 tactggatca gcgaaggtcc gcgccctggc gtcgggtatt tttacgcctt gacgccagtt
    22081 tatctggcga accggttgca ggcgcttttg ggtgtcgagc agaccatccg gatggagaac
    22141 tttttcttgc ctggtacgtt gccgatgggg gttaccattc ttgatgaaaa tggtcatacc
    22201 ctgatttcgc ttaccggacc agaaagcaaa attaagggcg atcctcgctg gatgcaggaa
    22261 cgctcctggt ttggctatac ggaagggttc cgggagctgg tgctgaagaa aaatctgcca
    22321 ccctcatcgc taagcatcgt gtattcggtg ccggttgata aggtactgga acgcattcgc
    22381 atgttgatcc ttaacgcaat tttgctgaat gtgcttgccg gagctgcatt gtttactctc
    22441 gcgcggatgt acgagcgacg tattttcatt ccggcggaaa gcgacgccct gcgactggaa
    22501 gaacatgagc agtttaatcg caagattgtc gcctccgcgc cagtgggtat ctgcattttg
    22561 cgtaccgctg atggcgtcaa tattttaagt aacgaactgg cgcataccta tctcaatatg
    22621 cttacgcatg aggatcgcca acggctgaca caaattatct gtgggcagca ggtcaatttt
    22681 gttgatgtcc tgaccagcaa caataccaat ctgcaaatca gcttcgtcca ttcgcgctat
    22741 cgtaatgaaa acgtggccat ttgtgtgctg gtggatgttt cttcgcgcgt gaagatggaa
    22801 gagtcgttgc aggagatggc acaagcagcg gaacaggcga gccagtcaaa atcgatgttc
    22861 cttgccaccg tcagtcatga gctgcgaacg ccgctgtatg gcattatcgg taacctggat
    22921 ctgttgcaaa ccaaagagtt accgaaaggc gtcgatcgtc tggtgacggc aatgaacaac
    22981 tcttccagcc tgttgttgaa aattatcagc gatattctcg atttctcgaa aattgaatca
    23041 gaacagttga agatcgaacc gcgtgagttt tcaccgcgtg aagtgatgaa ccacatcacc
    23101 gccaactatt taccgctggt ggtacgcaag cagttaggct tgtactgctt tattgaaccg
    23161 gatgtgccag tggccttaaa tggcgacccg atgcgtttac agcaggtcat ctccaacctg
    23221 ttgagtaacg ccataaaatt caccgatacc ggctgtatag ttttgcaagt tcgcgctgat
    23281 ggcgattatc tctctatccg tgttcgcgat accggcgtgg ggattccggc gaaagaagtc
    23341 gtgcgcttgt ttgatccctt cttccaggtc ggaacgggcg tacagcgaaa cttccagggg
    23401 accggtctgg gtctggcgat ttgtgaaaaa ctgatcagca tgatggacgg cgacatctcg
    23461 gtagattcag aaccgggaat gggcagccag tttaccgtgc gtattccgtt gtacggcgct
    23521 cagtacccgc agaaaaaagg cgtggaaggg ttgagtggta aacgctgctg gctggcggtc
    23581 cgcaatgcgt cgctctgtca gttcctggaa accagtttgc agcgcagcgg catcgtcgtt
    23641 acaacatacg aagggcagga accgactccc gaagatgtgt taattactga cgaggtagtg
    23701 agtaaaaaat ggcagggtag agcggtagtg accttctgtc gtcgccatat tggtattccg
    23761 ctggagaaag cgccagggga gtgggtacac agtgtggctg ccccgcatga gctaccggca
    23821 ttgttggcgc gtatttattt gatcgagatg gagagcgacg atcctgctaa cgctctgccg
    23881 tcgacggaca aagcggtcag cgataacgat gatatgatga ttctggtcgt ggatgatcat
    23941 ccgattaacc ggcgtcttct ggcagatcag ttgggatcgt tgggttatca atgtaaaacc
    24001 gcgaatgatg gcgtcgatgc gcttaatgta cttagcaaga atcatattga tatcgtgctt
    24061 agcgacgtca acatgccaaa tatggatggt taccgcttga cgcaacgcat tcgtcagttg
    24121 ggactgacgt tgccggtaat cggagtaact gctaatgcgt tggctgaaga gaagcagcgg
    24181 tgtctggagt ccggtatgga cagctgcctg tcgaagccgg taacgctgga tgtgataaaa
    24241 cagacgctaa cggtatatgc cgagagggtc aggaaatcgc gggattcgta ggacggataa
    24301 ggcgtttaca ccgcatctgg cattcagtgc aaatgccaga taagacacta acgcgtctta
    24361 tctggcctac aggtgattag tctttatctg ccggacttaa cgtcactgaa gagagataat
    24421 tcagcagggc gatatcgttc tcgacaccca gcttcatcat cgcagatttc ttctggctac
    24481 tgatggtttt aatactgcgg ttcagctttt tagcgatctc ggtcaccagg aagccttccg
    24541 caaacaggcg cagaacttca ctctcttttg gcgagagacg cttgtcaccg taaccaccag
    24601 cactgatttt ttccaacagg cgagaaacgc tttccggggt aaatttcttc cctttctgca
    24661 gcgcggcgag agctttcggc agatcggtcg gtgcaccttg tttcagcacg atcccctcga
    24721 tatccagatc caataccgca ctaagaatcg ccgggttgtt gttcatagtc agaacaatga
    24781 tcgacaggct tgggaaatgg cgcttgatgt acttgattaa ggtaatgcca tcgccgtact
    24841 tatcgccagg catggagaga tcggtaatca acacatgcgc atccagtttc ggcaggttgt
    24901 tgatcagtgc tgtagagtct tcaaattcgc cgacaacatt cacccactca atttgctcaa
    24961 gtgatttgcg aataccgaac aagactatcg gatggtcatc ggcaataatt acgttcatat
    25021 tgttcatgta ataggctacc ttgctacagc aagctcttga cataactgtc aatgtcgctg
    25081 atgtattttt ctattcctgg aacatccttc tcacgaatca gatgttccag cgtttcacat
    25141 aactgcttgc cgggtaccag atttagcatg gcaaatacgc ctttaagacg atgagccgtt
    25201 tgggctaacg cagcaaagtc actggttgct gcttcagtat acagcctctt aacatcatcc
    25261 ggtactgtgt ctacaaagag cgcataatag ccgctggcat ggagttgcgc attttcatct
    25321 ccgcccagag gcgattctgt cacctcttcc tgcgccagtt gcacttcaat taattgtaag
    25381 accgcttcct gcatagcgtt gctcatattg aagttgacgc acaattgacc aggcccaatt
    25441 tcccgtacgc cagactcatc atcgcttaaa agcaagccag aggcagtaag attagacgga
    25501 ttatccgtta aaaagatatc ataatcttga ctaattaatc tttcatcggg tgtgatacag
    25561 gttgcacccc aattttctaa ctggcgagtg acaatattcc gaatttctgc cgaagtaaca
    25621 tccaccatta cgcagacatc atccagtaat cgctcttctt cctcttcaac tttcgggtca
    25681 gctgcgagca ttttgatatg cacagagtag cgtgtaccaa gcccatcccg cgttttgatg
    25741 tttaaatgac cgcccagttt acgcgccagt tgatcgctca gccagaatgc cagcgggtcc
    25801 gccttgccat agcgatcgtt ttgggtctgg ttgataaacg ggaagtgcaa attatccatt
    25861 tcatgaatgc ttacgccttc tccggtgtcc agaatgcgga acgtcaggcg gtcttcggag
    25921 gactcatcct gatcaacctc aagggtgatt tttcccaatt gcgttgaggt cacggcatat
    25981 tgcatcagta gcagcaaaat acgtcgtaag gcatcgcgat cgccgcggcg catatcgtgt
    26041 gctttcagat gattgttaat cagcagttgc agacctttac gcttgatggc aggcaacact
    26101 gaaggcacaa cttcatcaat taaatcctgc acggagaaca gcaccgtctc acttttccag
    26161 ctatcgtccg caagcatgtt cgctaactgt atttcatcga ccagccgcac cagcacatct
    26221 gcctgattcg ccagttgttt gccttccggg gcgttgagtt tagccgcgct ctccgccagg
    26281 gactgtgcgg gttctttcag cgcatcgcca atgtttttca taaaggtcat ccgcccctgc
    26341 tggttttttt catacagacg ctgcgcctgc ttgagtttct tgtttaccag cacttcgcga
    26401 tcctgatcgc gaataatgaa aatttgtgtg cgcggcgcaa cctggctgcg gaacatgcgg
    26461 atctcataca gctcgttatt gatcgtcgcc tgaataatcc cctgatgctg ttccgccatg
    26521 gtggtgatgt tttgcagatt caaatgcggc agcaaatgat cggcaatttt gttacttatg
    26581 actgtgcggt tcgattcctg atcgtgaacc agcaggccga gcggcagcag tgagactatc
    26641 tcttcattaa ttgcccgtaa aatgcgcaat tcgttattga ccgccgtgct ggggacgctt
    26701 tctgtactgc ggctggagaa atggcggaat gtggtatagc caaataacgc cagcgccagc
    26761 aaaccgatgt tcagcagcag tggcagcaga atgttttgca acgtatccag caataaggtg
    26821 ccataaggaa cctgccagac caggcgcata tcggtagagt tgagtgccga ggagatttca
    26881 atcttcgtac tgttaaagtg gatactgacg ctatccgtcc cttctttctc attatcattg
    26941 tctcccgttg ccgtcgcgtc tggctcaagg cggaaactgt ccagcggcat gcccggtggg
    27001 atcaaatcat taatcggcag atcaaaagcc acgaccgttg ccagatgtcc cggctggttg
    27061 aacgtggtac gcaaggtaaa gtaatgaccg ttctgccagg ccaggcggcg catgttagaa
    27121 aagctttcgc gttcatcgag ggcgttggcc tgttgcaaca tctctgcacg acgtgaatca
    27181 acaatgtcgc tgacggtcga ttctttaaat ccggaggtga gatctttgag gggcagggtt
    27241 gagatcagca ccagactgtt atcctgacca ttcaggtaat acatcgacca cggtacattt
    27301 tctgcgcccc acaatgtgtc cagataggtg gacatccgtt gagtcatctc aagcgttgag
    27361 ttgtcgtgag agccaaagat taacgcttcc gttttgcggc gtggtttctc cagatagtag
    27421 acatcctgtt tcaggcgcgt ctcttgtaaa ccttcgccgg aggaggggga ggtcgtcgcg
    27481 gcaatgttgt cgtagatctg ccaggtcacg taacgccagg tatcgacgcg cttttggatt
    27541 gcgtgggtaa tgtcgacaat ctggtaactt ttatctttca gccaggcgtt aacggcactt
    27601 tgtaccatta cccccatcgt caccagtaac acaatgatca acagtaaaaa gaagcgggta
    27661 atgctccccg gtaggagtga aaagcgggtc gtggccgttg tctctttctg acgcattcgt
    27721 gtttatgacc tgttaaaact tcgcgaagtg atagggcagt ataaagggta cagtgtgaaa
    27781 ttccagactc ttacctgatt gatgattttc tattctcccg tgatatttat catcctgcat
    27841 tgggggaaat agatgtacaa gcgccatttt gctgtacaaa taacctacaa aaagcccaat
    27901 gaaattaatt gcaaataaac gaagattgct ggaaattatg ctgatgttaa ttatttgtga
    27961 aatagttaac aagcgttata gtttttctgt ggtagcacag aataatgaaa agtgtgtaaa
    28021 gaagggtaaa aaaaaccgga tgcgaggcat ccggttgaaa taggggtaaa cagacattca
    28081 gaaatgaatg acggtaataa ataaagttaa tgatgatagc gggagatatt ctagttgcga
    28141 gtgaaggttt tgttttgaca ttcagtgctg tcaaatactt aagaataagt tattgatttt
    28201 aaccttgaat tattattgct tgatgttagg tgcttatttc gccattccgc aataatctta
    28261 aaaagttccc ttgcatttac attttgaaac atctatagcg ataaatgaaa catcttaaaa
    28321 gttttagtat catattcgtg ttggattatt ctgcattttt ggggagaatg gacctgccga
    28381 ctgattaatg agggttaatc agtatgcagt ggcataaaaa agcaaataaa ggcatataac
    28441 agagggttaa taacatgaaa gttaaagtac tgtccctcct ggtcccagct ctgctggtag
    28501 caggcgcagc aaacgctgct gaaatttaca acaaagacgg caacaaatta gatctgtacg
    28561 gtaaagttga cggcctgcac tatttctccg ataacgactc taaagatggc gacaagacct
    28621 acatgcgtct tggcttcaaa ggtgaaactc aggttactga tcaactgacc ggttatggtc
    28681 agtgggaata tcagattcaa ggtaacgaac ctgaaagtga caatagttcc tggacccgtg
    28741 tggcattcgc tggtctgaaa ttccaggacg ttggttcttt tgactatggt cgtaactacg
    28801 gcgttgttta cgatgttact tcctggaccg acgtactgcc agaattcggt ggtgatacct
    28861 acgattctga taacttcatg cagcagcgtg gtaacggttt cgcgacctac cgtaacaccg
    28921 acttcttcgg tctggttgac ggtcttgatt ttgctgttca gtatcagggt aaaaacggta
    28981 gtgctcatgg cgaaggtatg accactaatg gccgtgatga tgtatttgag cagaacggtg
    29041 acggtgttgg tggttctatt acttacaatt atgaaggctt tggtatcggt gctgcagttt
    29101 ccagctccaa acgtacctgg gatcagaaca acactggcct gatcggtact ggcgaccgtg
    29161 ctgaaaccta cactggtggt ctgaaatacg acgctaacaa catctacctg gctgctcagt
    29221 acacccagac ctacaacgca actcgcgtag gttccctggg ttgggcgaac aaagcacaga
    29281 acttcgaagc tgttgctcag taccagttcg acttcggtct gcgtccgtcc ctggcttacc
    29341 tgcagtctaa aggtaaaaac ctgggtcgtg gctacgacga cgaagatatc ctgaaatatg
    29401 ttgatgttgg tgcgacctac tacttcaaca aaaacatgtc cacctacgtt gactacaaaa
    29461 tcaacctgct ggacgacaac cagttcaccc gcgctgctgg catcaacact gatgacatcg
    29521 tagctctggg tctggtttac cagttctaat ctcgatttat atcgaacaaa gggcctgcgg
    29581 gccctttttt cattgttttc agcgtacaaa cacagttttt tggtgtactc ttgcgaccgt
    29641 tcgcatgagg ataatcacgt atggaaataa gctttacccg cgtggcactg ctggctgccg
    29701 cgctcttctt tgttggttgc gatcaaaaac cacaacccgc caaaacccac gctactgaag
    29761 ttaccgttct tgaaggcaaa actatgggta ccttctggcg tgccagcatc ccgggcattg
    29821 acgccaaacg cagtgccgaa cttaaagaaa agattcagac ccagctggac gccgacgatc
    29881 agctgctttc gacctataaa aaagattccg cgctgatgcg ctttaacgac tcgcaaagtt
    29941 tgtcgccgtg gccagtaagt gaagcgatgg ccgatatcgt caccacctcg ctgcgcattg
    30001 gcgcgaagac cgatggcgcg atggatataa ccgtcgggcc gctggtgaat ctgtggggtt
    30061 tcggtccgga acaacagccg gttcaaattc cgagccagga acagatcgat gcgatgaaag
    30121 ccaaaaccgg cttacagcac ctgacggtga ttaatcagtc ccaccagcaa tatctgcaaa
    30181 aagacctgcc ggatttatat gtcgatctct ctaccgtcgg tgaaggttat gcggcggatc
    30241 atctggcact cttgatggag caggaaggga tttcccgcta tctggtgtcg gtgggcggcg
    30301 cgctgaacag ccgtggtatg aacggtgaag gccagccgtg gcgagtggcg attcaaaaac
    30361 caaccgataa agaaaacgcg gttcaggcgg tggtggatat caacggccac ggtatcagca
    30421 cctccggcag ctatcgcaac tattacgaac tggacggcaa acgtctttct catgttatcg
    30481 atccgcaaac cgggcgtccc attgaacata atctggtatc cgtgacggtg attgccccga
    30541 cggcgctgga agccgacgcc tgggacacag gtttgatggt gctcgggccg gataaagcca
    30601 aagaagttgt tcgccgggaa gggctggcgg tctatatgat caccaaagag ggcgatagct
    30661 ttaaaacctg gatgtcgccg cagtttaaaa gcttccttat cagcgaaaaa aattaaagcg
    30721 caagattgtt ggtttttgtg cgatggtgac cgggcagact aaaggctatc cttaaccagg
    30781 gagctgatta tgaaaaacgc cacatgctta acagacgatc aacgctggca atctgtctta
    30841 gcccgcgacc cgaatgccga cggcgaattc gttttcgccg tgcgcaccac aggcatcttt
    30901 tgccgtccgt cttgccgcgc cagacatgct ttgcgggaaa acgtctcctt ctacgcaaat
    30961 gccagtgagg cactcaccgc cggatttcgc ccctgcaaac gctgccaacc cgataaagcc
    31021 aatgcccagc aacatcggtt ggataaaatc acccacgcgt gtcgacttct ggaacaggaa
    31081 acgcctgtaa cgctggaagc cttagccgac caggtggcga tgagtccatt tcatttgcat
    31141 cggttgttta aagcgactac cggaatgacg cctaaagcct ggcaacaggc ctggcgcgct
    31201 cgccgtttgc gcgaattgct ggcgaaaggg gagagcgtga ctacatctat tcttaacgcc
    31261 ggattccccg acagcagcag ttactaccgc aaagccgacg aaacgctggg catgacggct
    31321 aaacaattcc gtcacggtgg cgaaaatctg gcggtgcgtt acgcgctggc tgattgtgag
    31381 ctgggccgtt gcctggtggc agaaagcgag cgggggattt gcgcgatatt gctgggcgat
    31441 gatgacgcga cactaatcag cgagttgcag cagatgtttc ccgctgccga caacgcgcct
    31501 gccgatctga tgtttcagca acatgtgcgt gaagtgatcg ccagcctcaa tcaacgcgat
    31561 acgccgctga cgttaccgct ggacattcgc ggcactgctt ttcagcaaca agtctggcag
    31621 gccctgcgca cgataccttg cggtgaaacc gtcagttatc agcaactggc taatgccatc
    31681 ggcaaaccga aagcggtacg ggctgttgcc agcgcctgtg ccgccaacaa gctagctatc
    31741 gttatacctt gtcatcgggt ggtccgtggt gatggcacac tttccggtta ccgctggggc
    31801 gtgtcgcgca aagcgcaact gctgcgccgc gaagctgaga atgaggagag gtaatgttgg
    31861 atctgtttgc cgatgctgaa ccgtggcaag agccactggc ggctggtgcg gtaattttac
    31921 ggcgtttcgc ttttaacgct gcggagcaac tgatccgcga tattaatgat gttgccagcc
    31981 agtcgccgtt tcgccagatg gtcactccag gcggatatac catgtcggtg gcgatgacca
    32041 actgtgggca tctgggctgg acgacccatc ggcaaggtta tctctattcg cccattgatc
    32101 cgcaaacaaa taaaccgtgg cccgccatgc cgcagagttt tcatgattta tgccaacgtg
    32161 cggctacggc ggcgggctat ccagatttcc agccagatgc ctgtttgatc aaccgctacg
    32221 ttcctggcgc gaaactgtcg ctgcatcagg ataaagacga accggatctg cgcgcgccaa
    32281 ttgtttctgt ttctctgggc ttacccgcga tttttcaatt tggcggcctg aaacgaaatg
    32341 atccgctcaa acgtttgttg ttggaacatg gcgatgtggt ggtatggggt ggtgagtcgc
    32401 ggctgtttta tcatggcatt caaccgttga aagtgggggg gcatccactc accaccgact
    32461 gccgctacaa cctgacattc cggcaggcag gtaaaaaaga ataaaaataa gaattattat
    32521 tgctgtgcgc gcgaagatgt ttaaactgcg ggctgtaatt cattgtccgg gttttctgca
    32581 tggaacttct tgtacttgtc tggcggcagt atcgctggcc atttatcagt gtgatggcgc
    32641 taagcctcgc cagtgcggca ttaggcattg gcttaattgc ttttatcaat cagcgcctta
    32701 tcgaaacggc ggataccagt ctgctggtgt tgccggagtt tctgggatta ttgttgctgt
    32761 tgatggcagt cactctcgga tcgcaactgg cgctcaccac tttggggcat cacttcgttt
    32821 accgactgcg tagtgaattt atcaagcgga ttctggatac ccacgtcgag cgcattgaac
    32881 aacttggtag cgcttcgttg ctggcggggt taaccagcga tgtgcgcaat atcaccattg
    32941 cttttgtgcg tctgccggaa ctggtgcagg ggatcattct cactatcggt tccgcggcgt
    33001 atttgtggat gctgtcgggc aaaatgttgc tggtaacggc tatctggatg gcagtcacca
    33061 tctggggcgg ttttgtgctg gtggcgcggg tgtacaaaca tatggcgacc ctgcgtgaaa
    33121 ccgaagataa gctgtacacg gattttcaaa ccgtactcga agggcgcaaa gagctgactc
    33181 tgaaccggga acgcgccgag tatgtgttta acaacctcta cattcctgat gcgcaagagt
    33241 atcgccatca tattatccgc gcagacacct tccatcttag tgccgtgaac tggtcaaaca
    33301 tcatgatgct gggcgctatc ggcctggtgt tctggatggc gaacagtctc ggttgggctg
    33361 ataccaacgt tgccgcgacc tattcgttga cgctgttatt cctgcgtacg ccgctgcttt
    33421 cggcagttgg cgcattgccg acgctgctga cggcgcaggt ggcgtttaac aagctgaaca
    33481 aattcgcgct cgcacctttc aaagcagagt ttccacgccc gcaggcgttt cccaactggc
    33541 aaacgctgga gctgcgtaac gtgacgtttg cttatcagga taacgcgttt tccgttgggc
    33601 cgattaacct caccatcaaa cgtggcgaac tgctgtttct gattggtggc aacggtagcg
    33661 gaaaatcgac gctggcgatg ttgctgacgg gcttgtatca gccacaaagc ggcgaaatct
    33721 tgctggatgg caaacctgtc agcggcgaac aaccggaaga ttatcgcaaa ctgttttcgg
    33781 cagtgtttac cgatgtctgg ctgtttgatc aactgctggg gccggagggg caacccgcta
    33841 acccgcaact ggttgagaag tggctggcgc agctgaaaat ggctcataag cttgagttaa
    33901 gtaacgggcg tattgttaac ctgaagttat caaaagggca gaaaaaacgc gtcgcgctgt
    33961 tgctggcgct ggcagaagaa cgcgatatta tcctgctgga tgaatgggcg gcggatcagg
    34021 acccacactt ccgtcgtgag ttttatcagg tgctgctacc gctgatgcag gagatgggta
    34081 aaacgatttt cgccatcagt catgatgatc attactttat ccacgctgac cgcctgctgg
    34141 aaatgcgcaa cgggcaactt agcgagctga caggcgaaga gcgcgatgct gcttcgcgtg
    34201 atgccgttgc ccggacggca taatatttcg acgctgacct ggcggactgc tgccgccagg
    34261 tcaatatgct aaaaatccct tcgtttctaa t
//
LOCUS       DADXDL010000055        32276 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.055, whole genome shotgun sequence.
ACCESSION   DADXDL010000055 DADXDL010000000
VERSION     DADXDL010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32276)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32276)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32276
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.055"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(93..1490)
                     /gene="ccp"
                     /locus_tag="IRB70_002880"
     CDS             complement(93..1490)
                     /gene="ccp"
                     /locus_tag="IRB70_002880"
                     /EC_number="1.11.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c peroxidase"
                     /protein_id="HBC0632768.1"
                     /translation="MKMVSRITAIGLAGVAICYLGLSGYVWYHDNKRSKQADVQASAV
                     SENNKVLGFLREKGCDYCHTPSAELPAYYYIPGAKQLMDYDIKLGYKSFNLEAVRAAL
                     LANKPVSQSDLNKIEWVMQYETMPPTRYTALHWAGKVSDEERAEILAWIAKQRAEYYA
                     SNDTAPEHRNEPVQPIPQKLPTDAQKVALGFALYHDPRLSADSTISCAHCHALNAGGV
                     DGRKTSIGVGGAVGPINAPTVFNSVFNVEQFWDGRAATLQDQAGGPPLNPIEMASKSW
                     DEIIAKLEKDPQLKAQFLEVYPQGFSGENITDAIAEFEKTLITPDSPFDKWLRGDENA
                     LTAQQKKGYQLFKDNKCATCHGGIILGGRSFEPLGLKKDFNFGEITAADIGRMNVTKE
                     ERDKLRQKVPGLRNVALTAPYFHRGDVPTLDGAVKLMLRYQVGKELPQEDVDDIVAFL
                     HSLNGVYTPYMQDKQ"
     gene            1895..3544
                     /locus_tag="IRB70_002881"
     CDS             1895..3544
                     /locus_tag="IRB70_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-trehalase"
                     /protein_id="HBC0632769.1"
                     /translation="MLNQKIQNPNPDELMIEVDLCYELDPYELKLDEMIEAEPEPEMI
                     EGLPASDALTPADRYLELFEHVQSAKIFPDSKTFPDCAPKMDPLDILIRYRKVRRHRD
                     FDLRKFVENHFWLPEVYSSEYVSDPQNSLKEHIDQLWPVLTREPQDHIPWSSLLALPQ
                     SYIVPGGRFSETYYWDSYFTMLGLAESGREDLLKCMADNFAWMIENYGHIPNGNRTYY
                     LSRSQPPVFALMVELFEEDGVRGARRYLDHLKMEYAFWMDGAESLIPNQAYRHVVRMP
                     DGSLLNRYWDDRDTPRDESWLEDVETAKHSGRPPNEVYRDLRAGAASGWDYSSRWLRD
                     TGRLASIRTTQFIPIDLNAFLFKLESAIANISALKGEKETEALFRQKASARRDAVNRY
                     LWDDENGIYRDYDWRREQLALFSAAAIVPLYVGMANHEQADRLANAVRSRLLTPGGIL
                     ASEYETGEQWDKPNGWAPLQWMAIQGFKMYGDDLLGDEIARSWLKTVNQFYLEQHKLI
                     EKYHIADGVPREGGGGEYPLQDGFGWTNGVVRRLIGLYGEP"
     gene            complement(3595..4197)
                     /locus_tag="IRB70_002882"
     CDS             complement(3595..4197)
                     /locus_tag="IRB70_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBC0632770.1"
                     /translation="MQIVMFDRQSIFIHGMKISLQQRIPGVSIQGASQADELWQKLES
                     YPEALVMLDGDQDGEFCYWLLQKTVVQFPEIKVLITATDCNKRWLQEVIHFNVLAIVP
                     RDSTVETFALAVNSAAMGMMFLPGDWRTTPEKDIKDLKSLSARQREILTMLAAGESNK
                     EIGRALNISTGTVKAHLESLYRRLEVKNRTQAAMMLNISS"
     gene            4717..5616
                     /locus_tag="IRB70_002883"
     CDS             4717..5616
                     /locus_tag="IRB70_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417978.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0632771.1"
                     /translation="MDKIHAMQLFIKVAELESFSRAADFFALPKGSVSRQIQALEHQL
                     GTQLLQRTTRRVKLTPEGMTYYQRAKDVLSNLNELDGLFQQDATSISGKLRIDIPPGI
                     AKSLLLPRLSEFLYLHPGIELELSSHDRPVDILHDGFDCVIRTGALPEDGVIARPLGK
                     LTMVNCASPHYLTRFGYPQSPDDLTSHAIVRYTPHLGVHPLGFEVASVNGVQWFKSGG
                     MLTVNSSENYLAAGLAGLGIIQIPRIAVREALRAGRLIEVLPGYRAEPLSLSLIYPQR
                     RELSRRVNLFMQWLAGVMKEHLD"
     gene            5665..6678
                     /gene="yhjD"
                     /locus_tag="IRB70_002884"
     CDS             5665..6678
                     /gene="yhjD"
                     /locus_tag="IRB70_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000191259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YhjD"
                     /protein_id="HBC0632772.1"
                     /translation="MTQENEIKRPTQDLEHEPIKQLDNSEKGGKVSQALETVTTTAEK
                     VQRQPVIAHLIRATERFNDRLGNQFGAAITYFSFLSMIPILMVSFAAGGFVLASHPML
                     LQDIFDKILQNISDPTLAATLKNTINTAVQQRTTVGLVGLAVALYSGINWMGNLREAI
                     RAQSRDVWERSPQDQEKFWVKYLRDFISLIGLLIALIVTLSITSVAGSAQQMIISALH
                     LNSIEWLKPTWRLIGLAISIFANYLLFFWIFWRLPRHRPRKKALIRGTFLAAIGFEVI
                     KIVMTYTLPSLMKSPSGAAFGSVLGLMAFFYFFARLTLFCAAWIATAEYKDDPRMPGK
                     TQR"
     gene            7070..8392
                     /locus_tag="IRB70_002885"
     CDS             7070..8392
                     /locus_tag="IRB70_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MHS family MFS transporter"
                     /protein_id="HBC0632773.1"
                     /translation="MQATATTLDHEQEYTPINSRNKVLVASLIGTAIEFFDFYIYATA
                     AVIVFPHIFFPQGDPTAATLQSLATFAIAFVARPIGSAVFGHFGDRVGRKATLVASLL
                     TMGISTVVIGLLPGYATIGIFAPLLLALARFGQGLGLGGEWGGAALLATENAPPRKRA
                     LYGSFPQLGAPIGFFFANGTFLLLSWLLTDEQFMSWGWRVPFIFSAVLVIIGLYVRVS
                     LHESPVFEKVAKAKKQVKIPLGTLLTKHVRVTVLGTFIMLATYTLFYIMTVYSMTFST
                     AAAPVGLGLPRNEVLWMLMMAVIGFGVMVPVAGLLADAFGRRKSMVIITTLIILFALF
                     AFNPLLGSGNPILVFAFLLLGLSLMGLTFGPMGALLPELFPTEVRYTGASFSYNVASI
                     LGASVAPYIAAWLQTNYGLGAVGLYLAAMAGLTLIALLLTHETRHQSL"
     gene            complement(8571..10631)
                     /locus_tag="IRB70_002886"
     CDS             complement(8571..10631)
                     /locus_tag="IRB70_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417981.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AsmA family protein"
                     /protein_id="HBC0632774.1"
                     /translation="MSKAGKITAAISGAFLLLIVVAIILIATFDWNRLKPTINQKVSA
                     ELNRPFAIRGDLGVVWERQKQETGWRSWVPWPHVHAEDIILGNPPDIPEVTMVHLPRV
                     EATLAPLALLTKTVWLPWIKLEKPDARLIRLSEKNNNWTFNLASDDNKDANAKPSAWS
                     FRLDNILFDQGRIAIDDKVSKADLEIFVDPLGKPLPFSEVTGSKGKADKEKVGDYVFG
                     LKAQGRYNGEPLTGTGKIGGMLALRGEGTPFPVQADFRSGNTRVAFDGVVNDPMKMGG
                     VDLRLKFSGDSLGALYELTGVLLPDTPPFETDGRLVAKIDTEKSSVFDYRGFNGRIGD
                     SDIHGSLVYTTGKPRPKLEGDVESRQLRLADLGPLIGVDSGKGAEKSTRSEQKKGEKS
                     VQPAGKVLPYDRFETDKWDVMDADVRFKGRRIEHGSSLPISDLSTHIILKNADLRLQP
                     LKFGMAGGSIAANIHLEGDKKPMQGRADIQARRLKLKELMPDVELMQKTLGEMNGDAE
                     LRGSGNSVAALLGNSNGNLKLLMNDGLVSRNLMEIVGLNVGNYIVGAIFGDDEVRVNC
                     AAANLDIANGVARPQIFAFDTENALINVTGTASFASEQLDLTIDPESKGIRIITLRSP
                     LYVRGTFKNPQAGVKAGPLIARGAVAAALATLVTPAAALLALISPSEGEANQCRTILS
                     QMKK"
     gene            complement(10701..11468)
                     /gene="pdeH"
                     /locus_tag="IRB70_002887"
     CDS             complement(10701..11468)
                     /gene="pdeH"
                     /locus_tag="IRB70_002887"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417982.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-guanylate-specific phosphodiesterase"
                     /protein_id="HBC0632775.1"
                     /translation="MIRQVIQRISNPEASIESLQERRFWLQCERAYTWQPIYQTCGRL
                     MAVELLTVVTHPLNPSQRLPPDRYFTEITVSHRMEVVKEQIDLLAQKADFFIEHGLLA
                     SVNIDGPTLIALRQQPKILRQIERLPWLRFELVEHIRLPKDSTFASMCEFGPLWLDDF
                     GTGMANFSALSEVRYDYIKIARELFVMLRQSPEGRTLFSQLLHLMNRYCRGVIVEGVE
                     TPEEWRDVQNSPAFAAQGWFLSRPAPIETLNTAVLAL"
     gene            11700..12629
                     /gene="kdgK"
                     /locus_tag="IRB70_002888"
     CDS             11700..12629
                     /gene="kdgK"
                     /locus_tag="IRB70_002888"
                     /EC_number="2.7.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417983.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxygluconokinase"
                     /protein_id="HBC0632776.1"
                     /translation="MSKKIAVIGECMIELSEKGADVKRGFGGDTLNTSVYIARQVDPA
                     ALTVHYVTALGTDSFSQQMLDAWHGENVDTSLTQRMENRLPGLYYIETDSTGERTFYY
                     WRNEAAAKFWLESEQSAAICEELANFDYLYLSGISLAILSPTSREKLLSLLRECRANG
                     GKVIFDNNYRPRLWASKEETQQVYQQMLECTDIAFLTLDDEDALWGQQPVEDVIARTH
                     NAGVKEVVVKRGADSCLVSIAGEGLVDVPAVKLPKEKVIDTTAAGDSFSAGYLAVRLT
                     GGSAEDAAKRGHLTASTVIQYRGAIIPREAMPA"
     gene            complement(12725..14221)
                     /locus_tag="IRB70_002889"
     CDS             complement(12725..14221)
                     /locus_tag="IRB70_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBC0632777.1"
                     /translation="MQGTKIRLLAGGLLMMATAGYVQADALQPDPAWQQGTLSNGLQW
                     QVLTTPQRPSDRVEIRLLVNTGSLAESTQQSGYSHAIPRIALTQSGGLEAAQARSLWQ
                     QGIDPKRPMPPVIVSYDTTLFNLSLPNNRNDLLKEALSYLANATGKLTITPETINHAL
                     QSQDMVATWPADTKEGWWRYRLKGSTLLGHDPADPLKQPVEAEKIKDFYQKWYTPDAM
                     TLLVVGNVDARSVVDQINKTFGELKGKRETPAPVPTLSPLRAEAVSIMTDAVRQDRLS
                     IMWDTPWQPIRESAALLRYWRADLAREALFWHVQQALSASNSKDIGLGFDCRVLYLRA
                     QCAINIESPNDKLNSNLNLVARELAKVRDKGLPEEEFNALVAQKKLELQKLFAAYARA
                     DTDILMGQRMRSLQNQVVDIAPEQYQKLRQDFLNSLTVEMLNQDLRQQLSNDMALILL
                     QPKGEPEFNMKALQAAWDQIMAPSTAAAATSVATDDVHPEVTDIPPVQ"
     gene            complement(14441..15727)
                     /gene="dctA"
                     /locus_tag="IRB70_002890"
     CDS             complement(14441..15727)
                     /gene="dctA"
                     /locus_tag="IRB70_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C4-dicarboxylate transporter DctC"
                     /protein_id="HBC0632778.1"
                     /translation="MKTSLFKSLYFQVLTAIAIGILLGHFYPEIGEQMKPLGDGFVKL
                     IKMIIAPVIFCTVVTGIAGMESMKAVGRTGAVALLYFEIVSTIALIIGLIIVNVVQPG
                     AGMNVDPATLDAKAVAVYADQAKDQGIVAFIMDVIPASVIGAFASGNILQVLLFAVLF
                     GFALHRLGSKGQLIFNVIESFSQVIFGIINMIMRLAPIGAFGAMAFTIGKYGVGTLVQ
                     LGQLIICFYITCILFVVLVLGSIAKATGFSIFKFIRYIREELLIVLGTSSSESALPRM
                     LDKMEKLGCRKSVVGLVIPTGYSFNLDGTSIYLTMAAVFIAQATNSQMDIVHQITLLI
                     VLLLSSKGAAGVTGSGFIVLAATLSAVGHLPVAGLALILGIDRFMSEARALTNLVGNG
                     VATIVVAKWVKELDHKKLDDVLNNRAPDGKTHELSS"
     gene            complement(15910..17898)
                     /gene="hmsP"
                     /locus_tag="IRB70_002891"
     CDS             complement(15910..17898)
                     /gene="hmsP"
                     /locus_tag="IRB70_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417986.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm formation regulator HmsP"
                     /protein_id="HBC0632779.1"
                     /translation="MRVSRSLTIKQMAMVAAVVLVFVFIFCTVLLFHLVQQNRYNTAT
                     QLESIARSVREPLSSAILKGDIPEAEAILASIKPAGVVSRADVVLPNQFQALRKSFIP
                     ERPLPVMVTRLFELPVQISLGVYSLERPANPQPIAYLVLQADSFRMYKFVMSTLSTLV
                     TIYLLLSLILTVAISWCINRLILHPLRNIARELNAIPAQELVGYQLALPRLHQDDEIG
                     MLVRSYNLNQQLLQRHYEEQNENAMRFPVSDLPNKALLMEMLEQVVARKQTTALMIIT
                     CETLRDTAGVLKEAQREILLLTLVEKLKSVLSPRMILAQISGYDFAVIANGVQEPWHA
                     ITLGQQVLTIMSERLPIERIQLRPHCSIGVAMFYGDLTAEQLYSRAISAAFTARHKGK
                     NQIQFFDPQQMEAAQQRLTEESDILNALENHQFAIWLQPQVEMTSGKLVSAEVLLRIQ
                     QPDGSWDLPDGLIDRIECCGLMVTVGHWVLEESCRLLAAWQERGIMLPLSVNLSALQL
                     MHPNMVADMLELLTRYRIQPGTLILEVTESRRIDDPHAAVAILRPLRNAGVRVALDDF
                     GMGYAGLRQLQHMKSLPIDVLKIDKMFVEGLPEDSSMIAAIIMLAQSLNLQMIAEGVE
                     TEAQRDWLAKAGVGIAQGFLFARPLPIEIFEESYLEEK"
     gene            complement(17980..21453)
                     /gene="bcsC"
                     /locus_tag="IRB70_002892"
     CDS             complement(17980..21453)
                     /gene="bcsC"
                     /locus_tag="IRB70_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026226.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsC"
                     /protein_id="HBC0632780.1"
                     /translation="MRKFTLNIFTLSLGLAVMPMVEAAPTAQQQLLEQVRLGEATHRE
                     DLVQQSLYRLELIDPNNPDVVAARFRSLLRQGDIDGAQKQLDRLSQLAPSSNAYKSSR
                     TTMLLSTPDGRQALQQARLQATTGHAEEAVASYNKLFNGAPPEGDIAVEYWSTVAKIP
                     ARRGEAINQLKRINADTPGNTGLQNNLALLLFSSDRRDEGFAVLEQMAKSNAGREGAS
                     KIWYGQIKDMPVSDASVQALKKYLSIFSDGDSVAAAQSQLAEQQKQLADPAFRARAQG
                     LAAVDSGMAGKAIPELQQAVRANPKDSEALGALGQAYSQKGDRANAVANLEKALALDP
                     HSSNNDKWNSLLKVNRYWLAIQQGDAALKANNPDRAERLFQQARNVDNTDSYAVLGLG
                     DVAMARKDYPAAERYYQQTLRMDSGNTNAVRGLANIYRQQSPEKAEAFIASLSASQRR
                     SIDDIERSLQNDRLAQQAEALENQGKWAQAAALQRQRLALDPGSVWITYRLSQDLWQA
                     GQRSQADTLMRNLAQQKPNDPEQVYAYGLYLSGHDQDRAALAHINSLPRAQWNSNIQE
                     LVNRLQSDQILETANRLRDSGKEQDAEAMLRQQPPSTRIDLTLADWAQQRRDYTAART
                     AYQNVLARESNNADAILGLTEVDIAAGDKAAARSQLAKLPATDNASLNTQRRVALVQA
                     QLVDTAAAQQTFNKLIPQAKSQPPSMESAMVLRDGAKFEAQAGDPKQALETYKDAMVA
                     SGVTTTRPQDNDTFTRLTRNDEKDDWLKRGVRSDAADLYRQQDLNVTLEHDYWGSSGT
                     GGYSDLKAHTTMLQVDAPYSDGRMFFRSDFVNMNVGSFSTNADGKWDDNWGTCTLQDC
                     SGNRSQSDSGASVAVGWRNDVWSWDIGTTPMGFNVVDVVGGISYSDDIGPLGYTVNAH
                     RRPISSSLLAFGGQKDSPSNTGKKWGGVRADGVGLSLSYDKGEANGVWASLSGDQLTG
                     KNVEDNWRVRWMTGYYYKIINQNNRRVTIGLNNMIWHYDKDLSGYSLGQGGYYSPQEY
                     LSFAIPVMWRERTENWSWELGASGSWSHSRTKTMPRYPLMNLIPTDWQEEAARQSNDG
                     GSSQGFGYTARALLERRVTSNWFVGTAIDIQQAKDYAPSHFLLYVRYSAAGWQGDMDL
                     PPQPLIPYADW"
     gene            complement(21435..22541)
                     /gene="bcsZ"
                     /locus_tag="IRB70_002893"
     CDS             complement(21435..22541)
                     /gene="bcsZ"
                     /locus_tag="IRB70_002893"
                     /EC_number="3.2.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulase"
                     /protein_id="HBC0632781.1"
                     /translation="MNVLRSGLVTMLLLAAFSVQAACNWPAWEQFKKDYISQEGRVID
                     PSDARKITTSEGQSYGMFFALAANDRAAFDNILDWTQNNLAQGSLKERLPAWLWGKKE
                     NSKWEVLDSNSASDGDVWMAWSLLEAGRLWKEQRYTDIGSALLKRIAREEVVTVPGLG
                     SMLLPGKVGFAEDNSWRFNPSYLPPTLAQYFTRFGAPWTTLRETNQRLLLETAPKGFS
                     PDWVRYEKDKGWQLKAEKTLISSYDAIRVYMWVGMMPDSDPQKARMLNRFKPMATFTE
                     KNGYPPEKVDVATGKAQGKGPVGFSAAMLPFLQNRDAQAVQRQRVADNFPGSDAYYNY
                     VLTLFGQGWDQHRFRFSTKGELLPDWGQECANSH"
     gene            complement(22548..24887)
                     /gene="bcsB"
                     /locus_tag="IRB70_002894"
     CDS             complement(22548..24887)
                     /gene="bcsB"
                     /locus_tag="IRB70_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis cyclic di-GMP-binding
                     regulatory protein BcsB"
                     /protein_id="HBC0632782.1"
                     /translation="MKRKLFWICAVAMGMSAFPSFMTQATPATQPLINAEPAVAAQTE
                     QNPQVGQVMPGVQGADAPIVAQNGPSRDVKLTFAQIAPPPGSMVLRGINPNGSIEFGM
                     RSDEVVTKAMLNLEYTPSPSLLPVQSQLKVYLNDELMGVLPVTKEQLGKKTLAQMPIN
                     PLFITDFNRVRLEFVGHYQDVCENPASTTLWLDVGRSSGLDLTYQTLNVKNDLSHFPV
                     PFFDPRDNRTNTLPMVFAGTPDTGLQQASAIVASWFGSRSGWRGQNFPVLYNQLPNRN
                     AIVFATNDKRPDFLHDHPAVKAPVIEMINHPQNPYVKLLVVFGRDDKDLLQAAKGIAQ
                     GNILFRGESVVVNEVKPLLPRKPYDAPNWVRTDRPVTFGELKTYEEQLQSSGLEPAAI
                     NVSLNLPPDLYLMRSTGIDMDINYRYTMPPVKDSSRMDISLNNQFLQSFNLSSKQEAN
                     RLLLRIPVLQGLLDGKTDVSIPALKLGATNQLRFDFEYMNPMPGGSVDNCITFQPVQN
                     HVVIGDDSTIDFSKYYHFIPMPDLRAFANAGFPFSRMADLSQTVTVMPKAPNEAQMET
                     LLNTVGFIGAQTGFPAINLTVTDDGSTIQGKDADIMIVGGIPDKLKDDKQIDLLVQAT
                     ESWVKTPMRQTPFPGIVPDESDRAAETQSTLTSSGAMAAVIGFQSPYNDQRSVIALLA
                     DSPRGYEMLNDAVNDSGKRATMFGSVAVIRESGINSLRVGDVYYVGHLPWFERLWYAL
                     ANHPILLAVLAAISVVLLAWVLWRLLRIISRRRLNPDNE"
     gene            complement(24898..27516)
                     /gene="bcsA"
                     /locus_tag="IRB70_002895"
     CDS             complement(24898..27516)
                     /gene="bcsA"
                     /locus_tag="IRB70_002895"
                     /EC_number="2.4.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417990.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-forming cellulose synthase catalytic
                     subunit"
                     /protein_id="HBC0632783.1"
                     /translation="MSILTRWLLIPPVNARLIGRYRDYRRHGASAFSATLGCFWLILA
                     WIFIPLEHPRWQRIRAEHKNLYPHINASRPRPLDPVRYLIQTCWLLIGTSRKETPKPR
                     RRTFSGLQNIRGRYHQWMNELPERVSHKTQHLDEKKELGHLSAGARRLILGIIVTFSL
                     ILALICVTQPFNPLAQFIFLMLLWGVALIVRRMPGRFSALMLIVLSLTVSCRYIWWRY
                     TSTLNWDDPVSLVCGLILLFAETYAWIVLVLGYFQVVWPLNRQPVPLPKDMSLWPSVD
                     IFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGREEFRQFAQNVGVKYIART
                     THEHAKAGNINNALKYAKGEFVSIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHF
                     FSPDPFERNLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIA
                     VETVTEDAHTSLRLHRRGYTSAYMRIPQAAGLATESLSAHIGQRIRWARGMVQIFRLD
                     NPLTGKGLKFAQRLCYVNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALMIALFV
                     LPHMIHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGG
                     LVEEEYVDWVISRPYIFLVLLNLVGVAVGIWRYFYGPPTEMLTVVVSMVWVFYNLIVL
                     GGAVAVSVESKQVRRSHRVEMTMPAAIAREDGHLFSCTVQDFSDGGLGIKINGQAQIL
                     EGQKVNLLLKRGQQEYVFPTQVARVMGNEVGLKLMPLTTQQHIDFVQCTFARADTWAL
                     WQDSYPEDKPLESLLDILKLGFRGYRHLAEFAPSSVKGIFRVLTSLVSWVVSFIPRRP
                     ERSETAQPSDQALAQQ"
     gene            complement(27513..28265)
                     /gene="bcsQ"
                     /locus_tag="IRB70_002896"
     CDS             complement(27513..28265)
                     /gene="bcsQ"
                     /locus_tag="IRB70_002896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsQ"
                     /protein_id="HBC0632784.1"
                     /translation="MAVLGLQGVRGGVGTTTITAALAWSLQMLGENVLVVDACPDNLL
                     RLSFNVDFTHRQGWARAMLDGQDWRDAGLRYTSQLDLLPFGQLSIEEQENPQHWQTRL
                     SDICSGLQQLKASGRYQWILIDLPRDASQITHQLLSLCDHSLAIVNVDANCHIRLHQQ
                     ALPDGAHILINDFRIGSQVQDDIYQLWLQSQRRLLPILIHRDEAMAQCLAAKQPVGEY
                     RSDALAAEEILTLANWCLLNYSGLKTPVGSAS"
     gene            complement(28277..28465)
                     /locus_tag="IRB70_002897"
     CDS             complement(28277..28465)
                     /locus_tag="IRB70_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhjR family protein"
                     /protein_id="HBC0632785.1"
                     /translation="MNNNEPDTLPDPAIGYIFQNDILALKQAFSLPDIDYADISQREQ
                     LAAALKRWPLLAEFAQQK"
     gene            28737..30308
                     /gene="bcsE"
                     /locus_tag="IRB70_002898"
     CDS             28737..30308
                     /gene="bcsE"
                     /locus_tag="IRB70_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsE"
                     /protein_id="HBC0632786.1"
                     /translation="MRDIVDPVFSIGISSLWDELRHMPAGGVWWFNVDRHEDAISLAN
                     QTIASQAETAHVAVISMDSDPAKIFQLDDSQGPGKITLFSMLNHEKGLYYLARDLQCS
                     IDPHNYLFILVCANNAWQNIPAERLRSWLDKMNKWSRLNHCSLLVINSGNNNDKQFSL
                     LLEEYRSLFGLASLRFQGDQHLLDIAFWCNEKGVSARQQLSVQQQNGCWTLVQHQEAE
                     IQPRSDEKRILSNVSVLEGAPPLSEHWQLFNNNEVLFNEARTAQAATVVFSLQQNAQI
                     EPLARSIHTLRRQRGSAMKILVRENTASLRATDERLLLACGANMVIPWNAPLSRCLTM
                     IESVQGQKFSRYVPEDITTLLSMTQPLKLRGFQKWDVFCNAVNNMMNNPLLPAHGKGV
                     LVALRPVPGIRVEQALTLCRPNRTGDIMTIGGNRLVLFLSFCRINDLDTALNHIFPLP
                     TGDIFSNRMVWFEDDQISAELVQMRLLAPEQWGMPLPLTQSSKPVINAEHDGRHWRRI
                     PEPMRLLDDAVERSS"
     gene            30305..30496
                     /gene="bcsF"
                     /locus_tag="IRB70_002899"
     CDS             30305..30496
                     /gene="bcsF"
                     /locus_tag="IRB70_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417994.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsF"
                     /protein_id="HBC0632787.1"
                     /translation="MMTISDIIEIIVVCALIFFPLGYLARHSLRRIRDTLRLFFAKPR
                     YVKPAGTLRRTEKARATKK"
     gene            30493..32172
                     /gene="bcsG"
                     /locus_tag="IRB70_002900"
     CDS             30493..32172
                     /gene="bcsG"
                     /locus_tag="IRB70_002900"
                     /EC_number="2.7.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cellulose biosynthesis protein BcsG"
                     /protein_id="HBC0632788.1"
                     /translation="MTQFTQNTAMPSSLWQYWRGLSGWNFYFLVKFGLLWAGYLNFHP
                     LLNLVFAAFLLMPIPRYSLHRLRHWIALPIGFALFWHDTWLPGPESIMSQGSQVAGFS
                     TDYLIDLVTRFINWQMIGAIFVLLVAWLFLSQWIRITVFVVAILLWLNVLTLAGPSFS
                     LWPAGQPTTTVTTTGGNAAATVAATGGAPVVGDMPAQTAPPTTANLNAWLNNFYNAEA
                     KRKSIFPSSLPADAQPFELLVINICSLSWSDIEAAGLMSHPLWSHFDIEFKNFNSATS
                     YSGPAAIRLLRASCGQTSHTNLYQPANNDCYLFDNLSKLGFTQHLMMGHNGQFGGFLK
                     EVRENGGMQTELMDQTNLPVVLLGFDGSPVYDDTAVLNRWLDVTEKDKNSRSATFYNT
                     LPLHDGNHYPGVSKTADYKARAQKFFDELDAFFTELEKSGRKVMVVVVPEHGGALKGD
                     RMQVSGLRDIPSPSITDVPVGVKFFGMKAPHQGAPIVIDQPSSFLAISDLVVRVLDGK
                     IFSEDNVDWKKLTSGLPQTAPVSENSNAVVIQYQDKPYVRLNGGDWVPYPQ"
BASE COUNT         7618 a         8830 c         8114 g         7714 t
ORIGIN      
        1 taatataaac atttaatatg ataatattaa aaacagactt tattatcgta ataaaaatcg
       61 cccaaacact cctgttcggg cgatcaaatt aattattgtt tatcctgcat atacggcgtg
      121 taaaccccgt tcagactgtg caggaaagct acgatatcat ccacatcctc ctgcggcagc
      181 tctttgccta cctgatagcg cagcatcagt ttcaccgccc cgtccagcgt cggcacgtca
      241 ccgcgatgga agtacggtgc cgttaaagca acgttacgta aaccgggtac tttctgacgc
      301 aatttatcac gctcttcttt agtaacattc atacgaccaa tatccgccgc cgtaatttca
      361 ccaaagttaa agtctttttt cagccccaac ggttcaaagg aacgtccgcc gagaataata
      421 ccaccatgac aagttgcaca tttattatct ttaaataatt gatagccttt tttctgttgc
      481 gccgtcagag cattctcatc tccacgcaac catttatcaa atggggaatc cggcgtaatt
      541 aatgttttct caaattcagc aatggcatca gtaatatttt cgccactgaa accttgcgga
      601 tagacttcga ggaactgcgc tttaagctgc ggatcttttt ccagcttagc aataatttcg
      661 tcccaggatt tcgacgccat ttcaatcggg ttcaacggcg gtccaccagc ctgatcctgc
      721 aatgttgccg cacgaccatc ccagaactgc tcaacgttaa atactgagtt aaataccgtc
      781 ggcgcgttaa tcggccccac tgcgccacca acaccaatcg atgtttttct gccatcgacg
      841 ccccccgcat tcaacgcatg gcaatgagcg catgaaatgg tgctatcagc cgataaacgg
      901 ggatcgtgat acagcgcaaa acccaacgcc actttttgcg catcggtagg cagtttttgc
      961 gggatgggct gcaccggttc attgcgatgc tccggagcag tatcattgct ggcgtaatat
     1021 tccgcgcgct gttttgcaat ccaggccagt atttccgccc gctcttcatc actcacctta
     1081 cccgcccagt gtagcgcggt ataacgcgtt ggcggcatag tttcatactg catcacccat
     1141 tcaatcttat tcagatcgct ttgcgaaacg ggtttattag ccagcagagc cgcacgcacg
     1201 gcctcgaggt taaaagattt atatccaagc tttatgtcgt aatccatcaa ctgtttcgcg
     1261 ccgggaatat aataataggc gggtaattct gccgaaggtg tatggcaata gtcgcatcct
     1321 ttttcacgga gaaagcctaa aaccttatta ttttcactga cagcagatgc ctgaacatcg
     1381 gcctgtttac tgcgtttatt atcgtggtac cacacataac cagataaccc taaatagcaa
     1441 atcgcgacgc cagccaggcc gatcgcggta atacgtgaga ccattttcat tattcttccc
     1501 tcacggtggt gagttattgt gacccagaaa attttccaga atgctgcaaa cgtctctgcg
     1561 agacaaagcc atcataaaaa acagggagat atgctttttg ataggaatca atcaattaca
     1621 tgaatataaa ctatcaataa gatagccagt gcctattacc cagatcagga atggcatatc
     1681 atgattgcgg cgagagcagg attgaatgtt ctgaaaatga aaaacaacac gaaatccgta
     1741 tttttataaa ttccattgat attagtgcgt tatatttttt ggcaggttaa taaacgtgat
     1801 ccaccgcacg ctttgtcgcc caccaggcgg agcgaatgac tacccttaaa gaaaagcccg
     1861 ataattagcg acgaatttcg gaggtcggat ccttatgctc aatcagaaaa ttcaaaaccc
     1921 taatccagac gaactgatga tcgaggtcga tctctgctat gagctggacc cgtatgaatt
     1981 aaaactggat gagatgatcg aggcagaacc ggaacccgag atgattgaag ggctgcccgc
     2041 ctctgatgcg ctgacgcctg ccgatcgcta tctcgaactg ttcgagcatg ttcagtcggc
     2101 gaaaattttc cccgacagta aaacctttcc cgactgcgca cccaaaatgg acccgctgga
     2161 tattttaatc cgctaccgta aagtgcgccg tcatcgtgat tttgacttgc gcaagtttgt
     2221 tgaaaaccac ttctggctgc cggaggtcta ctccagcgag tatgtatcgg acccgcaaaa
     2281 ttccctgaaa gagcatatcg accagctgtg gccggtgcta acccgtgaac cacaggatca
     2341 cattccgtgg tcttctctgc tggcgctgcc gcagtcatat attgtcccgg gcggccgttt
     2401 tagcgaaacc tactattggg attcctattt caccatgctg gggctggcgg aaagtggtcg
     2461 ggaagatttg ctgaaatgca tggccgataa cttcgcctgg atgatcgaaa actacggcca
     2521 catccccaac ggcaaccgca cctattattt gagccgctcg caaccaccgg tttttgcgct
     2581 gatggtggag ttgtttgaag aagatggtgt acgcggcgcg cgccgctatc tcgaccacct
     2641 gaaaatggaa tatgccttct ggatggacgg tgcagaatcg ttgatcccta atcaggccta
     2701 tcgccatgtt gtgcggatgc cggacggctc gctgctcaat cgttactggg acgatcgcga
     2761 cacgccgcgt gacgaatcct ggcttgagga cgttgaaacc gcgaaacatt ctggtcgccc
     2821 gcctaacgag gtgtaccgcg atttacgtgc gggggcggcc tccggttggg attactcttc
     2881 ccgttggctg cgtgatactg gtcgtctggc gagcattcgt accacccagt tcatccccat
     2941 cgatctgaat gccttcctgt ttaaactgga gagcgccatc gccaacatct cggcgctgaa
     3001 aggcgagaaa gagacagaag cactgttccg ccagaaggcc agtgcccgtc gcgatgcggt
     3061 aaaccgttac ctctgggatg atgaaaacgg catctaccgc gattacgact ggcgacgcga
     3121 gcaactggcg ctgttttccg ctgccgccat tgtgccgctc tatgtcggta tggcgaacca
     3181 tgaacaggcc gatcgtctgg caaacgccgt gcgcagccgg ttactgacac ctggcgggat
     3241 tctggcaagc gagtacgaaa ccggtgaaca gtgggataaa cccaacggct gggcaccgtt
     3301 acaatggatg gcgattcagg gatttaaaat gtatggcgat gaccttctgg gtgatgaaat
     3361 cgcgcgcagc tggctgaaga cggtgaatca gttctatctg gaacagcaca aactgatcga
     3421 gaaataccat attgccgatg gtgttccccg cgaaggcggc ggtggcgagt atccgttgca
     3481 ggatgggttt ggctggacta acggtgtggt gcgccgttta attggtttgt acggtgaacc
     3541 ataatatttt tacagccagc cgctaacttc ctgctggctg taaaattatc ctcttcagga
     3601 ggagatattt aacatcattg ccgcctgggt gcgatttttc acttccagac ggcgatacag
     3661 ggattccaga tgcgctttta ccgttccggt actgatattc agcgccctgc cgatctcctt
     3721 atttgattcg cccgccgcta acatggttaa aatctcccgc tggcgggcgc ttaacgattt
     3781 gagatcttta atgtcctttt ccggcgtcgt ccgccagtct ccaggcagaa acatcatccc
     3841 catcgccgca ctatttaccg ccaacgcaaa tgtctcgacg gttgaatcac gaggcacaat
     3901 ggccagcaca ttaaaatgga taacttcctg taaccaccgt ttattgcaat ccgtcgccgt
     3961 aattaacacc ttaatctcag gaaattgcac cacggttttt tgcagcaacc agtagcaaaa
     4021 ctcaccatcc tgatcgccat cgagcatcac taaggcttca gggtaacttt ccagcttttg
     4081 ccataactcg tctgcctgac tggccccctg aatactcact cctggaatac gctgctgtaa
     4141 actgattttc attccatgaa taaatattga ctgcctgtca aacatgacta tttgcataac
     4201 tgaatctcca cctgaatatg ttaaaaagac ttaagtagtg gaagggtatt acccgcgaga
     4261 aaaaataaga attcgtcatt tggcggtggc cattctacag agatgacgcg tagaaaatag
     4321 ttgccgatat aaatagttac agctaaacgc ctgaaattac atgtcgaggg cactatttaa
     4381 aacaattttg cggatttcct tatattgatg gttagtacgc atgcaattaa aaatgaaact
     4441 ccgcgaccac aagcaaaaat aacaaatggc aatgagacaa aaataagcac aaatggccaa
     4501 cacgtcctct gttcacttta aagggaatcg ctgaaaaaaa cgctctattt agggaaattc
     4561 acctttctca taaagctatt ccgccctttt cctgctggga aatcgccaca ttcgtcatga
     4621 caacattgtg aaacccggca ttagatgtta gaaaaaacaa taaacattgc gatattcgcg
     4681 ttactgtttc gctgtgaaca acaatcggtc aaagaaatgg ataaaattca cgcaatgcag
     4741 ttgttcatca aagtcgcgga gctggaaagt ttttcccgcg cggcggattt ctttgctttg
     4801 ccaaagggaa gtgtttcgcg ccagatacag gcactggaac atcaacttgg cacccagctt
     4861 ctccagcgca ctacgcgacg ggtcaaactc acgccagaag gcatgaccta ttatcaacgg
     4921 gcaaaagatg tgttgagtaa tctcaacgaa ctggacggtc tgtttcaaca ggatgccacc
     4981 agtatcagcg gtaaattacg catcgacatc ccgccaggaa tcgcgaaaag cctgttactg
     5041 ccgcgtctgt cggaatttct ctatctgcat ccgggaattg agctggagct gagtagccat
     5101 gaccgtccgg tagatattct tcatgatggt tttgattgcg tgatacgcac tggcgcgtta
     5161 ccggaagatg gcgttatcgc ccgtcccctc ggcaaactga ccatggtcaa ctgtgccagt
     5221 ccgcactatc tgacgcgctt tggttatccg caaagccccg acgatctgac ttcgcacgca
     5281 atagtgcgtt acacaccgca cctgggtgta catccgttag gttttgaggt tgccagcgtt
     5341 aatggcgtcc agtggtttaa gtctggcggc atgttgacgg taaacagtag cgaaaactat
     5401 ctcgccgccg gtcttgccgg tctggggatt attcagatcc cgcgcattgc cgtgcgcgaa
     5461 gccctgcgtg ccgggcggct tattgaagta ttacctggct accgtgccga gccgctctcc
     5521 ctttcgctga tttatccgca gcgtcgggag ctttcccggc gtgtaaacct gtttatgcag
     5581 tggctggctg gcgtaatgaa agagcacctg gactgaccga ctatactttt taagaatgac
     5641 cacgacagaa ggacaaaaga gcggatgacg caggaaaacg agatcaaacg tcccacccag
     5701 gatctggagc acgagccgat taagcagttg gataatagcg agaaaggcgg caaagttagc
     5761 caggcgctgg aaaccgtcac cactactgcc gagaaagtcc aacgccaacc ggttattgcg
     5821 cacctgattc gcgcaacaga gcgctttaac gatcggctgg gtaaccagtt tggtgcggct
     5881 atcacctatt tctcattttt gtcgatgatc ccgattttga tggtgtcgtt tgccgcaggg
     5941 ggctttgtgc tggcctccca tccgatgttg ctacaggata tcttcgacaa aattctgcaa
     6001 aacatcagcg atccgacgct agccgccacg ttgaaaaaca ccatcaacac cgccgttcag
     6061 cagcgtacta ccgtagggct tgtcggcctg gcggtggcgc tttattccgg catcaactgg
     6121 atgggtaacc tgcgtgaagc gattcgcgcc cagtcacgcg atgtctggga acgctcgccg
     6181 caagatcagg agaagttctg ggtaaaatat ctgcgtgatt ttatttcgct gattggtttg
     6241 ttgattgcgc tgattgtgac gctttcgatc acctcggttg ccggttcggc gcagcaaatg
     6301 attattagcg ccctgcacct gaacagcatt gagtggctga aaccgacgtg gcggttgatt
     6361 ggcctggcga tttccatctt cgccaactat ctgcttttct tctggatctt ctggcgcttg
     6421 ccgcgccacc gtccgcgcaa aaaagccctg attcgcggaa catttctggc tgcgattggt
     6481 tttgaagtga ttaaaatcgt gatgacctac accctgccat cgctgatgaa atccccctct
     6541 ggcgcagcat ttggttccgt gctggggctg atggcgtttt tctacttctt cgcccgtttg
     6601 acgctgtttt gcgcggcgtg gattgccacc gccgaatata aagacgaccc gcgaatgccg
     6661 gggaaaacgc agcggtaatt caatgattta taatgcctga taaacgcacg gtcgatcccc
     6721 tcgccccttc ggggagagga ttagggtgag ggggtacaag ccagccagag accaggcaac
     6781 gacatgcaca taaccacctg aaactacatc tcttcaggag caaacaattt cataccaact
     6841 cataacccca gcatataaat ccagttggta acttttattt aacctgaaac cagttttatc
     6901 cactatttat aaaattatgt gaagcatttc atagaagaaa aatcactggc ctaaacatta
     6961 tccccttttt gcctggtttt tgaccatttc cgcgatttgt tacacattga aatatcactt
     7021 ttgctgtgcg taatatggct attcgttagc caaaaaataa gaaaagatta tgcaagcaac
     7081 agccacaaca ctcgaccacg agcaagaata cacgccgatc aactcgcgta ataaagtcct
     7141 tgtcgcctct ctcattggca cggccattga gttcttcgac ttttacattt acgccactgc
     7201 ggccgttatt gtgtttccgc atatcttctt cccgcagggc gatccaacgg cagcaacgct
     7261 acagtcgctc gccaccttcg ccatcgcctt cgtcgcgcgc cccattggct ctgccgtttt
     7321 tggtcatttt ggcgatcgcg ttgggcgtaa agcgacgctg gtcgcctcgt tgctaacgat
     7381 ggggatttcg accgtggtga ttggtctgct gccgggctat gccacgattg gtattttcgc
     7441 cccgctgctg ctggcactgg ctcgatttgg tcagggtctg ggcttaggcg gcgaatgggg
     7501 cggagcggcg ctgctggcga ctgaaaacgc cccaccgcgc aaacgtgcac tgtatggctc
     7561 cttcccgcaa ctgggcgcac cgattggctt cttctttgcc aatggcactt tcttgctgct
     7621 ttcctggcta ctgaccgacg agcagtttat gagctggggc tggcgtgtgc catttatctt
     7681 ctcggcggtg ctggtcatta tcggtctgta tgttcgcgtg tcgctgcatg agtcgccggt
     7741 gtttgagaaa gtcgctaaag cgaaaaaaca ggtgaagatc ccgctgggta cgctgctgac
     7801 caaacatgtt cgcgtaaccg tactgggtac gttcattatg ctggcaacct atacgctgtt
     7861 ttacatcatg acggtctact ctatgacctt tagtaccgcc gccgcgccag ttgggcttgg
     7921 cctgccgcgt aacgaagtgt tgtggatgct gatgatggca gtgattggtt ttggcgtgat
     7981 ggtgccagtc gccggattac tggctgatgc ctttggtcgc cgtaaaagca tggtaatcat
     8041 caccacgctg atcatcctgt tcgcgctgtt cgcctttaac ccgttgctcg gttctggcaa
     8101 cccgattctg gtttttgcct tcctgctgct ggggttaagt ctgatggggc tgaccttcgg
     8161 tccgatgggc gcgctgttac cagagctgtt cccgacagaa gtgcgttaca ccggagcatc
     8221 gttctcttac aacgtagcgt cgattctcgg ggcttccgtt gcgccgtata tcgcagcctg
     8281 gttgcagact aactacgggt taggtgcggt ggggttatat ctggcggcga tggctggctt
     8341 gacgttaatc gccctgctgc tgacccatga gacgcgacat cagtcgttgt aataagagtg
     8401 aaaagcctga tgcgctacgc ttatcaggcc agaatttcca tacaatatat tgaattagca
     8461 aggatttgta agccggaggc gttcacgccg catccggcat gaacaaagca cactttgcca
     8521 acaatctaaa tctgtttaat tgccggatgt cagacatccg gcaattatca tcacttcttc
     8581 atctgcgaca aaattgtcct gcactgatta gcctcccctt cggaaggtga gatcagcgcc
     8641 agtaacgccg ccgccggtgt taccagcgtt gccagtgccg ccgcaacggc tccgcgagca
     8701 atcaacggcc cggctttcac cccagcctgc ggatttttaa acgtcccacg tacatacagc
     8761 ggcgaacgca atgtgataat ccgaatccct ttactctccg gatcaatagt caaatccagc
     8821 tgttccgaag caaaacttgc cgtaccggta acgttaatca acgcgttctc agtatcgaaa
     8881 gcaaaaatct gcgggcgcgc cacgccgttg gcaatatcca gattcgccgc cgcacagttc
     8941 acccgcacct catcatcacc aaatatcgca ccgacaatgt agttaccgac attcagcccg
     9001 acaatctcca tcaggttgcg gctcaccagc ccgtcattca tcagcagttt caggttgccg
     9061 ttactgttgc ctaaaagcgc cgccaccgag ttaccgctac cgcgtagttc cgcgtcaccg
     9121 ttcatttccc ccagcgtctt ctgcatcagt tccacatcgg gcatcagttc tttcagtttc
     9181 agtcgacgag cctgaatatc tgcccgccct tgcatcggtt ttttatcacc ttccagatga
     9241 atattcgccg caatgctgcc gcccgccatg ccaaatttca gcggttgcag gcgcaggtca
     9301 gcatttttga ggatgatatg agtagaaaga tcgctaatcg gcaggctact gccatgctca
     9361 atgcgccgcc ctttgaagcg aacatcggca tccataacgt cccatttatc ggtttcgaag
     9421 cggtcataag gcagcacttt gcccgcaggc tgaacgcttt tttcaccctt cttctgttca
     9481 gaccgtgtcg acttttcagc tcctttcccg gaatcaacgc caatcaacgg tcccaggtcc
     9541 gccagccgca attgccgcga ctcgacatca ccttccagtt ttggtcgtgg cttgccggtg
     9601 gtgtagacca gagaaccgtg gatatcgcta tcgccaatgc gcccattaaa gccgcgataa
     9661 tcaaagaccg acgatttttc agtgtcgatt ttcgctacca gccgaccatc cgtttcaaac
     9721 ggcggggtat cgggcagcag aacgcccgtc agttcataga gagcacccag cgaatcgcca
     9781 gaaaatttaa gccgtaaatc gacacccccc atcttcattg ggtcattcac aacgccatca
     9841 aaagcaacac gggtgttacc agagcggaaa tcagcctgta ccggaaacgg cgtcccttcg
     9901 ccacgcagcg ccagcatacc gcctattttt cccgtacccg tgagcggttc accgttataa
     9961 cgtccctgcg ccttcaggcc aaaaacgtaa tcgcccacct tttctttatc cgctttacct
    10021 ttcgatccag taacttcgct gaacggcagc ggcttgccta acggatcaac aaaaatctcc
    10081 agatccgctt tgcttacttt gtcatcaatc gcgatccgcc cttgatcgaa cagaatatta
    10141 tccagccgaa acgaccacgc cgacggcttt gcattcgcgt ctttgttgtc atcgctggca
    10201 agattaaacg tccagttatt gttcttttcg gagaggcgaa tcaggcgcgc gtcgggcttt
    10261 tcgagcttga tccacggcaa ccagaccgtt ttggtcagca gcgccagcgg ggccagcgtc
    10321 gcttctactc gcggcaaatg caccattgtg acttcgggaa tatccggtgg attgccaaga
    10381 atgatgtctt ccgcgtgtac atggggccac ggcacccagc tgcgccagcc agtttcttgc
    10441 ttttgccgct cccacaccac gcccagatcg ccacggatag cgaacggacg attcaactcc
    10501 gcagagactt tctggttgat ggtcggtttg agtcgattcc agtcaaaagt tgcaatcaaa
    10561 atgatcgcca cgacaatcaa caacaagaaa gcccctgaaa tcgcagcggt tattttgcct
    10621 gccttgctca tcgttcgctt cctcatattc ttcctgtgcc agtcctaaag atagtccagc
    10681 caggcggaaa atgaggcagc ttatagcgcc agaaccgccg tattcagcgt ttctatcggt
    10741 gccgggcgtg aaagaaacca gccttgtgcg gcgaatgcgg gcgagttctg tacatcgcgc
    10801 cactcttccg gcgtttctac gccctcgacg atcaccccac gacaatagcg attcatgaga
    10861 tgtaaaagct gagaaaagag tgtgcgtcct tccggcgact gacgcagcat cacaaacagt
    10921 tctcgcgcga ttttgatgta gtcataacgc acttcactta gtgcagagaa atttgccatc
    10981 ccggtaccaa aatcatccag ccacagcggg ccaaattcac acatcgaggc aaaggttgaa
    11041 tctttcggca gacggatatg ctccaccagt tcgaaacgca gccagggaag acgctcaatc
    11101 tggcgcagga tttttggttg ctgacgcagg gcgatgagcg tagggccatc aatattgacc
    11161 gatgccagca ggccgtgctc tataaagaag tcggcttttt gcgccagcaa atcaatctgc
    11221 tctttcacaa cctccatccg atggctaacg gtgatttcag taaaatagcg atccggcggc
    11281 aggcgttgcg aagggttcaa gggatgcgtg accaccgtta atagctccac ggccattaac
    11341 cgtccgcagg tttgatagat cggctgccag gtgtaagcac gctcacactg caaccaaaaa
    11401 cgccgttcct gcaagctctc gatgcttgct tcagggttgc ttattcgctg gataacctgc
    11461 cttatcatca aagatgtcct gtgtttaaaa gtgatgctgc ccggactcga caaagattat
    11521 cggcgcgcaa gggcagaact ttaccgcctg gccggggtaa atttccctac tccacaacgg
    11581 aatctttcag gaatacgttc tggctcaaaa aaataatgga acactgtttt aatatggttg
    11641 accagcaaac caccacagcg caaactaacg ctaatttttt acagatcagg ttcacgacta
    11701 tgtccaaaaa gattgccgtg attggcgaat gcatgattga gctttccgag aaaggcgcgg
    11761 acgttaagcg cggtttcggc ggcgataccc tgaacacttc cgtctatatc gcccgtcagg
    11821 tcgatcctgc ggcattaacc gttcattacg taacggcgct gggaacggac agttttagcc
    11881 agcagatgct ggacgcctgg cacggcgaga acgttgatac ttccctgacc caacggatgg
    11941 aaaaccgtct gccgggcctt tactacattg aaaccgacag caccggcgaa cgtacgttct
    12001 actactggcg taacgaagcc gccgccaaat tctggctgga gagtgagcaa tccgcggcga
    12061 tttgcgaaga gctggcgaat ttcgattatc tctacctgag cgggattagc ctggcgatct
    12121 taagcccgac cagccgcgaa aagctgcttt ccctgctgcg cgaatgccgc gccaacggcg
    12181 gaaaagtgat tttcgacaat aactatcgtc cgcgcctgtg ggccagcaaa gaagagacac
    12241 agcaggtgta ccaacaaatg ctggaatgca cggatatcgc cttcctgacg ctggacgatg
    12301 aagacgcgct gtggggtcaa cagccggtgg aagacgtcat tgcgcgcacc cataacgcgg
    12361 gcgtgaaaga agtggtggtg aaacgcgggg cggattcttg cctggtgtcc attgctggcg
    12421 aagggttagt ggatgttccg gcggtaaaac tgccgaaaga aaaagtgatc gataccaccg
    12481 cagctggcga ctctttcagt gccggttatc tggcggtacg tttgacgggc ggcagtgcgg
    12541 aagacgcagc gaaacgcggg cacctgaccg caagtaccgt tattcagtat cgcggcgcga
    12601 ttatcccgcg tgaagcgatg ccagcgtaaa agcagcatat gcaaaaggct ggatagagtg
    12661 ttacccccct atccagctca tccataaata cctgatggtt gtgctaactc atcaccatca
    12721 ggcattactg tacaggtgga atatccgtca cttcaggatg tacgtcatcc gtggcgacag
    12781 atgtggcggc agccgcagtc gatggggcca tgatttgatc ccaggccgcc tgcaacgctt
    12841 tcatgttaaa ttccggctcg cctttcggct gcagcagtat taacgccata tcattcgaca
    12901 actgctgacg cagatcctga tttaacatct ccaccgtcag gctgttaagg aaatcctgac
    12961 gcagtttctg atattgctcc ggcgcgatat cgacgacctg attttgcaac gaacgcatcc
    13021 gctgccccat cagaatatcg gtatcagctc gcgcataggc ggcaaacagt ttctgcagct
    13081 ccagtttctt ttgcgccact aacgcattga actcttcttc cggcagacct ttatcgcgaa
    13141 ccttcgccag ttcacgcgcc accagattaa ggttgctgtt cagcttgtcg tttggtgatt
    13201 cgatgttgat ggcacactgc gcacgcagat acagcacacg acagtcaaat ccaagaccga
    13261 tgtctttact gttactggcg cttaacgctt gctgaacatg ccagaacagc gcctcacggg
    13321 ccaggtccgc acgccagtag cgcagcagtg cggctgattc acgaatcggc tgccacggcg
    13381 tatcccacat gatagatagc cggtcctgac gcaccgcgtc ggtcataata ctcaccgctt
    13441 ccgcacgcag cggagaaagc gtcggcaccg gagccggtgt ttcacgtttg cctttcagtt
    13501 cgccaaacgt tttattgatt tggtcgacga ccgagcgcgc atccacgttt cccaccacca
    13561 gcagcgtcat tgcatccggg gtgtaccatt tctgatagaa atctttaatc ttttccgctt
    13621 caacgggttg tttcagcgga tcggcaggat cgtgacctaa caaggttgat cctttcagac
    13681 gataacgcca ccaaccctct ttagtatcgg caggccaggt tgccaccatg tcctgacttt
    13741 gcaacgcatg gttgatggtt tctggcgtga ttgtcagttt gccagtggca tttgccagat
    13801 aagagagcgc ttctttcagc aagtcgttac ggttattggg caaactcaga ttaaacagcg
    13861 tggtgtcata agagacaatt accggcggca tcgggcgttt agggtcgatc ccctgttgcc
    13921 acaatgaacg cgcctgtgct gcttcaaggc caccgctttg cgttaacgca atacgaggga
    13981 tggcgtggct gtaaccgctc tgttgtgtac tttcggcgag cgaaccggta ttaaccagca
    14041 ggcgaatttc aacacgatcg ctgggacgct ggggcgtggt cagcacttgc cactgtaaac
    14101 cgttggaaag cgtcccctgt tgccatgctg gatcaggctg gagcgcatct gcctgcacat
    14161 agccagcagt ggccatcatc agcaaaccgc ccgctaaaag tcgaattttt gtgccctgca
    14221 tgtgaacccc tgatcaacta tcctggtaat aaaaaactgc ccgttgtcgg tcagtctaaa
    14281 tgacgttaaa aacacttcgt gttagaccgc aagaacatga aaatgtcacg gaagaagtga
    14341 aataaacctg aactcaccca ggtggtaagt tcaggcacag gggtcaatta tgcgcaaaca
    14401 cccgcactcg gggaagggag tgcgggcata agtggtgaga ttaagaggat aattcgtgcg
    14461 ttttgccatc cggcgcacga ttattcagca catcgtccag ttttttgtgg tccagttctt
    14521 tcacccactt agcaacgaca atggtcgcta cgccgttacc gaccaggtta gtcagcgcac
    14581 gagcttctga cataaagcgg tcgataccga ggatcagcgc cagacccgct accggcaaat
    14641 ggcccaccgc agagagcgtc gccgccagca cgataaagcc actgcccgtt accccggcag
    14701 cccctttgga agagagcaac aacacaatta atagcgtaat ttggtggacg atatccatct
    14761 gactgttagt ggcctgggcg ataaacaccg ccgccattgt caggtatatc gatgtgccat
    14821 caaggttaaa cgagtagcct gtcgggatga ccagccccac caccgatttg cggcagccga
    14881 gtttctccat cttgtcgagc atacgcggca gcgccgactc ggaagatgaa gtccccagta
    14941 caatcagcag ttcttcacgg atgtagcgga taaatttgaa gatactgaaa ccagtcgctt
    15001 tagcgattga acccagtacc agcaccacaa acaggataca ggtgatgtag aagcagataa
    15061 tcagctgccc cagttgcacc agtgtgccga cgccgtattt accgatggta aacgccattg
    15121 ccccgaacgc accaataggt gccagacgca tgatcatatt gatgatgccg aaaatgacct
    15181 gcgagaaact ttcgatgacg ttaaaaatca gttggccttt gctgcccaga cggtggagcg
    15241 caaaaccaaa cagtacggca aacagcagta cctgcagaat gttaccgctg gcaaatgcgc
    15301 caatgacgct cgccgggatg acatccataa tgaaggcgac aatgccctgg tctttcgcct
    15361 gatcggcgta aaccgctacc gctttcgcat caagcgttgc cggatcgacg ttcattccgg
    15421 caccaggctg cacgacgtta acgatgataa gaccaataat cagcgcgatg gtactgacaa
    15481 tttcaaagta aagcagtgcg actgcgccgg tacgaccgac cgccttcatg ctttccatgc
    15541 ccgcaatgcc cgttacgacg gtacaaaaga tgacaggagc gatgatcatc ttaatgagct
    15601 taacgaaccc gtcgccaagc ggtttcattt gctcgcctat ttcagggtag aaatggccaa
    15661 ggagaatacc aatggctatc gctgtcagga cctgaaagta aaggctttta aacagagagg
    15721 ttttcatagg gtgtccttta gtaaaaccac aggtcttgta aggttatggg gtacctgcgg
    15781 ccttaaaata acacccagac aacatcacag aaatgtacct ggatcataat tgaaacaaaa
    15841 aggttaaaaa gtttgagctg gctcgcacaa accagcactt tttaaagttt tgtaatcagt
    15901 ttggggtagc tacttttctt ccaggtaact ctcttcgaag atttcaatag ggagtgggcg
    15961 agcaaaaagg aagccctggg caataccaac gcccgctttt gccagccagt cgcgttgtgc
    16021 ttcagtctcc acgccttcgg caatcatttg taagttcagg ctttgcgcca acatgataat
    16081 tgcagcaatc atgctgctat cttccggcaa gccttcaaca aacattttgt cgatttttaa
    16141 cacgtcgatt ggcaacgatt tcatatgctg cagctgacgc agccctgcgt agcccatgcc
    16201 gaaatcatcc agcgccaccc gaacgccggc attacgcaac gggcggagga ttgccaccgc
    16261 tgcatgaggg tcgtcaatac gtcggctttc tgtcacttcc agaatcagtg ttcccggctg
    16321 aatgcgatag cgggttaaca gttccagcat atccgctacc atattcgggt gcatcagttg
    16381 cagcgctgag aggtttaccg acaagggcaa cataatgccg cgctcttgcc aggcagccag
    16441 cagtcgacag gactcttcca gcacccagtg accgacggta accatcagcc cacagcactc
    16501 aatgcgatcg attaagccat ccggcagatc ccaactgcca tccggttgct ggatacgcag
    16561 taacacttcc gcactgacca gtttaccgct ggtcatctcg acctgtggct gtaaccaaat
    16621 cgcaaactga tgattttcca gtgcattaag gatatcgctc tcttccgtca accgctgctg
    16681 ggcggcttcc atctgctgcg gatcaaagaa ctgaatctga ttcttacctt tatggcgagc
    16741 ggtaaatgcc gcagaaatag cgcgactgta aagctgttcg gcggtgagat cgccgtagaa
    16801 catcgccacg ccaatgctac agtgcggacg gagttgaata cgttcaatcg gcaggcgctc
    16861 gctcatgata gtgagcactt gctgacctaa agtgattgcg tgccacggtt cctgtacacc
    16921 attggcaatg acagcaaagt cataaccact aatctgcgcg aggatcatac gtggcgacag
    16981 taccgatttg agtttttcca ccagcgtcag cagcagaatt tctcgttgcg cctctttcag
    17041 cacgcccgca gtatcacgca gggtttcaca ggtgatgatc atcagcgcgg tggtttgttt
    17101 acgcgcgaca acctgctcca gcatctccat cagcaaggct ttgttcggca aatccgacac
    17161 cgggaagcgc atcgcgtttt cgttctgttc ttcataatgg cgctgcagca attgctggtt
    17221 gaggttgtaa ctgcgcacca gcataccgat ttcatcgtcc tgatgcagac gtggtaatgc
    17281 cagttggtaa ccaacaagct cctgggctgg gatggcgtta agttcacgag caatattgcg
    17341 taacggatgc aaaatcaggc ggttaatgca ccagctaatc gccaccgtca atattaacga
    17401 caaaagtaag taaatggtca ctaacgttga gagggtgctc atcacgaact tatacatgcg
    17461 gaaggaatcc gcctgtagca ccagataggc aattggctgc gggtttgccg gacgttcgag
    17521 cgagtagaca cccagcgaga tttgaaccgg tagctcaaac aggcgagtaa ccattaccgg
    17581 tagcggacgc tctggaataa aacttttacg cagcgcctgg aactggttag gcagcactac
    17641 atcggcacgg ctgaccacgc ctgccggttt aatgctggca agaatagctt ccgcttcggg
    17701 aatatcgcct ttcaaaatgg cagaagataa gggttcgcgg acagagcgag caatgctttc
    17761 cagttgcgta gccgtgttat agcgattctg ctggaccaga tggaacagca aaacggtgca
    17821 aaaaataaaa acgaacacca ggacaacggc tgccaccatt gccatctgct tgattgttaa
    17881 cgagcgactt acgcgcaaat tgtctccccc cggaaatccc agattgccgc ccgagtatac
    17941 ccgatcgcag cggcattaag agaggcgcta tctgaaaact taccagtcgg cgtaaggtat
    18001 cagcggctgc ggcggtaaat ccatgtcacc ctgccatccg gcggcggaat aacgtacgta
    18061 gagcaggaaa tggctgggtg cgtaatcttt cgcctgctgg atatcaattg ccgtgccgac
    18121 aaaccagttg gaagtaacac gtcgttcaag taatgcccgc gccgtatagc cgaagccctg
    18181 actgctgccg ccatcgttgg attgccgcgc agcttcttcc tgccagtcgg tcgggatcag
    18241 attcatcagc ggataacgcg gcatggtttt ggtgcgtgaa tgcgaccacg agccagacgc
    18301 ccccagctcc cacgaccagt tttccgtccg ctcccgccac atcaccggta tggcaaacga
    18361 caggtattcc tgcgggctgt agtaaccgcc ctgaccaagt gagtagccac tcaggtcttt
    18421 gtcgtaatgc cagatcatat tgttaagacc aatggtcaca cggcgattat tctggttgat
    18481 gatcttatag taatagcccg tcatccagcg cacgcgccag ttatcttcga catttttacc
    18541 ggttaactgg tcaccgctaa gcgatgccca gacgccgttt gcttcacctt tatcgtagct
    18601 caggcttagc cccacgccgt cggcacgcac gccgccccat tttttcccgg tattgctcgg
    18661 agagtctttt tgcccaccaa aggccagcaa agaactggag atgggccgac ggtgggcgtt
    18721 aacggtgtaa cccagcggcc cgatatcatc gctgtaactg atgccgccaa ccacatccac
    18781 cacgttgaag cccatcggcg tggtaccgat atcccagctc cagacgtcat ttcgccagcc
    18841 gaccgccacg ctggcaccgg aatccgactg gctgcggttg ccgctacaat cctgtaatgt
    18901 acaggtgccc cagttgtcat cccatttacc atcggcatta gtggagaaac tgccgacgtt
    18961 catattgacg aaatcactgc gaaagaacat ccgcccgtca gaatacggcg cgtccacctg
    19021 caacatagtg gtgtgcgctt tcagatcgga ataaccaccg gtgccgctcg aaccccagta
    19081 atcatgctca agggtgacgt taagatcctg ctggcgatag aggtccgccg catcgctgcg
    19141 cacgccgcgt ttcagccagt catctttctc gtcgttacgg gtcagtcggg taaaggtgtc
    19201 gttatcctgc ggacgcgtcg tggtcacacc ggatgcgacc atcgcgtctt tgtaggtttc
    19261 cagcgcctgc tttggatcgc ccgcctgcgc ttcaaacttc gcaccgtcgc gcagcaccat
    19321 cgcgctttcc atcgacggtg gctgagattt tgcctgcggg atcaacttat taaacgtctg
    19381 ctgcgccgct gcggtatcga caagctgtgc ctgcaccagc gccacgcgcc gctgagtgtt
    19441 cagcgaggcg ttatcggtgg cgggaagttt cgccagttga ctgcgcgccg cggctttgtc
    19501 gcctgcggca atatccactt ccgtcaggcc aagaatggca tcggcgttat tcgactcccg
    19561 cgccagcaca ttctgatacg ccgtgcgggc ggcggtgtaa tcgcgtcgct gttgtgccca
    19621 gtcagccagc gtaagatcaa tgcgcgtgga aggcggttgc tggcgtagca tcgcctccgc
    19681 atcctgttct ttgccactgt cacgcaggcg attagccgtt tccagaatct gatcgctttg
    19741 cagtcgatta accagctcct gaatattgct gttccattgc gcgcgcggca ggctgttgat
    19801 atgcgccagc gccgctctgt cctggtcatg accagagaga tacagcccgt aagcgtaaac
    19861 ctgctccggg tcgttcggct tctgctgtgc cagattgcgc attaatgtat cagcctggct
    19921 gcgttgtccg gcctgccaga gatcctgcga aagtcggtaa gtaatccata cgctgccggg
    19981 atccagcgcc agtcgttgcc gctgaagtgc tgccgcctgc gcccatttgc cctggttttc
    20041 cagtgcctct gcctgctgtg ccagacggtc gttttgtagg ctgcgttcga tatcatcaat
    20101 gctacgccgc tgactggcag agagcgaggc gataaacgct tcagcttttt ctggcgattg
    20161 ctggcggtaa atattcgcca gcccgcgcac ggcgttagtg ttgccgctgt ccatacgcag
    20221 ggtctgctga taatagcgtt cagcggcggg gtaatctttg cgcgccatcg ccacatcgcc
    20281 cagccccagc actgcatagc tgtcggtgtt atcgacatta cgcgcctgct ggaacaggcg
    20341 ttctgcccgg tcaggattat tggctttcag cgcagcatcg ccctgctgga tcgccagcca
    20401 gtagcggttt actttcagca gactgttcca tttgtcgttg ttgctgctgt gcggatccag
    20461 tgcgagggct ttttccagat tcgccaccgc attggcgcga tcgcctttct gagaatacgc
    20521 ctggcccagc gcccccagag cctcactgtc tttcgggttc gcccgcaccg cctgttgtag
    20581 ttcgggaatg gctttacccg ccatgccaga gtccaccgcc gctaaacctt gcgcacgagc
    20641 gcggaaagca gggtcggcca gctgtttttg ctgttctgcc agttgcgatt gcgcagccgc
    20701 tacgctatcg ccatcgctaa agatcgagag atattttttc agtgcctgaa cgctggcatc
    20761 gctgacgggc atgtctttaa tctgcccgta ccagatttta gaggccccct cgcgtccggc
    20821 gttcgatttc gccatttgtt ccagaacggc aaaaccttcg tcacggcgat cgctactaaa
    20881 cagtaatagc gccagattgt tttgcaggcc cgtgttgccc ggcgtatccg cattaatgcg
    20941 ttttagctga ttaatcgctt cgccacggcg ggccggaatt ttcgccaccg tactccagta
    21001 ctcgacagca atgtcacctt ccggcggcgc accgttgaac agtttgttgt aactcgccac
    21061 agcttcttcc gcatgaccgg tagttgcctg caatcttgcc tgttgcagtg cctgacgacc
    21121 atccggcgtg gaaagcagca tcgtagtccg cgacgattta tacgcatttg aactcggcgc
    21181 taactgcgac agccgatcga gctgtttttg tgcgccatca atatcgccct gacgtaacag
    21241 agaacgaaaa cgggcggcaa cgacgtccgg gttattcgga tcaataagtt ccagacgata
    21301 caacgactgt tgcaccaggt cttcacgatg ggtcgcttcg cctaaccgaa cttgctccag
    21361 caactgttgc tgagcggttg gtgctgcctc gaccatcggc atgacggcca gaccgaggga
    21421 aagcgtgaat atgtttagtg tgaatttgcg cattcctggc cccagtcagg taataactca
    21481 ccttttgtcg agaagcggaa acggtgttga tcccagcctt gtccaaacag ggtcagcaca
    21541 tagttgtaat aggcatcgct gccgggaaag ttatcggcca cgcgctggcg ctgaacggcc
    21601 tgtgcatcgc ggttttgtaa aaagggcagc atggcggcag aaaaaccgac cggtccttta
    21661 ccctgcgctt tccccgtagc cacatccact ttttctggcg gatagccgtt tttctcggtg
    21721 aatgtcgcca tcggtttaaa ccggttgagc atccgcgctt tttgcggatc gctgtcaggc
    21781 atcatgccta cccacatgta aacgcggatc gcgtcgtagc tgctgatcaa tgttttttcg
    21841 gcttttagct gccagccttt gtctttctca tagcgcaccc agtctggcga aaagcctttc
    21901 ggggcggttt ccagcaataa acgttgattg gtttcgcgca gcgtagtcca cggcgcgcca
    21961 aagcgggtga aatactgcgc cagcgtcggc ggcaggtagc tggggttaaa acgccagctg
    22021 ttatcctctg caaatcccac tttgcccggc aacaacatgg aacccagccc aggcaccgtc
    22081 accacttcct cccgcgcaat acgttttaac aacgcgctgc caatgtcggt ataacgctgc
    22141 tctttccaca aacgccccgc ctccagcaac gaccaggcca tccagacatc accatcggag
    22201 gccgaattgc tgtccagcac ttcccactta ctgttctctt tcttgcccca cagccatgcg
    22261 ggcaaacgtt cttttaaaga accctgagcg agattgttct gcgtccagtc gagaatatta
    22321 tcgaaagctg cacggtcgtt agccgccagg gcaaagaaca tgccgtaact ttgcccttcg
    22381 gaagtggtga ttttacgcgc gtcacttggg tcaatgacgc gcccttcctg actgatgtaa
    22441 tcctttttga actgctccca ggcaggccag ttgcaggctg cctgaacact aaaggcagcc
    22501 agcagcagca tcgtcacgag tccactacgc aacacattca tcttcaatta ctcgttatcc
    22561 gggttaagac gacgacggct gataatacgc agcaaacgcc acagtaccca tgccagcagc
    22621 acgacgctga ttgccgccag caccgccagc agaatcggat ggtttgccag ggcataccat
    22681 aagcgttcga accacggcag atggccaacg taatagacgt cgccaacgcg taggctattg
    22741 ataccggact cgcggatcac cgcgaccgaa ccgaacatgg tggcgcgttt gccgctatcg
    22801 ttcaccgcat cgttaagcat ttcataaccg cgtgggctat ctgccagcag cgcaatcacg
    22861 ctacgctggt cgttatacgg cgactggaag ccaatcaccg ctgccatcgc accggaagag
    22921 gtcagcgttg actgagtttc tgccgcgcga tcgctctcgt ccggtacaat gccggggaac
    22981 ggggtctggc gcatcggcgt tttcacccag ctttcggtcg cctgcaccaa cagatcgatc
    23041 tgcttatcgt ctttcagttt gtccgggata ccaccgacga tcatgatgtc ggcatctttg
    23101 ccctgaatgg tgctgccatc atcggtcacc gtcaggttaa tcgccgggaa gcccgtctgc
    23161 gcaccgataa agccaacggt attcagcaag gtttccatct gtgcttcgtt aggcgctttc
    23221 ggcatcacgg tgacggtttg tgacagatcc gccatccggc tgaacgggaa gcccgcgtta
    23281 gcaaaggcgc gtagatccgg catcggaatg aagtggtaat acttcgagaa gtcgatggtg
    23341 gaatcatcac caatcaccac atgattctgc accggctgga aggtaatgca gttatccacc
    23401 gaaccgcccg gcatcgggtt catatactca aagtcaaagc gcagctggtt ggtcgcgccc
    23461 agtttcagcg ccggaataga gacatccgtt ttgccatcca gcaaaccttg taataccgga
    23521 atccgcagca gcaggcggtt cgcctcctgt ttactgctca ggttgaagga ttgcaggaac
    23581 tggttattca ggctgatatc catccgcgaa ctgtctttca ccggcggcat ggtgtagcga
    23641 tagttgatat ccatatcaat gccggtactg cgcatcaggt agagatccgg cggcagattt
    23701 agcgaaacgt taatcgctgc tggctcaaga ccgctggatt gtaactgttc ttcataggtt
    23761 ttcagttcac caaaggtgac cggacgatcg gtacgcaccc agttcggcgc atcgtacggc
    23821 ttacgcggta gcagcggttt cacttcattc actaccacgc tttcaccacg gaacagaatg
    23881 ttaccctgag cgataccttt cgctgcctgc aacaggtctt tgtcgtcacg accaaacacc
    23941 accagcagtt tgacgtaagg attctgcgga tggttgatca tctcaatcac cggggctttt
    24001 accgccggat gatcgtgcag gaagtccggg cgtttgtcat tagtggcaaa aacaatggca
    24061 ttgcgattcg gcagttggtt atagagcacc gggaaattct gcccacgcca gccagaacgc
    24121 gaaccaaacc acgaggcgac aatagctgat gcttgttgca atccagtatc tggcgtaccc
    24181 gcaaagacca tcggcaaggt gttggtgcgg ttatcacgcg ggtcaaagaa tggtaccggg
    24241 aagtgtgaca ggtcattctt cacattcagg gtctgatagg tcaaatccag tccactgctc
    24301 cgcccaacat ccagccaaag cgtggtgctg gccgggtttt cgcacacgtc ctgataatgg
    24361 ccgacaaact ccagccgcac acggttgaag tcggtaataa acagtgggtt aatgggcatt
    24421 tgcgccagcg tttttttacc caactgttct ttggtcactg gcagcacgcc catcagctca
    24481 tcattgagat aaacctttaa ctgcgactgg acaggcagta acgatggcga tggcgtgtat
    24541 tcgaggttga gcatcgcctt cgtcaccact tcatcgctgc gcataccaaa ctcaatgctg
    24601 ccgttcgggt taatgccacg tagcaccatg ctgcccggcg gcggcgcgat ttgcgcaaag
    24661 gtcagcttca catcacgcga aggaccgttc tgcgccacga tgggggcatc agcgccctgc
    24721 acgcctggca tcacttgccc cacctgcgga ttttgttccg tctgggcggc tacagctggc
    24781 tcagcattga tcagtggttg cgttgctggc gtcgcctgcg tcatgaaaga ggggaacgca
    24841 ctcatcccca tagccactgc acaaatccag aatagttttc ttttcatcgc gttatcatca
    24901 ttgttgagcc aaagcctgat ccgatggttg tgccgtttcg ctccgctccg ggcggcgcgg
    24961 aataaacgat acaacccagg aaaccagaga agtcagcaca cggaatatgc ccttcaccga
    25021 agaaggcgca aactccgcca gatggcggta gccacggaag ccgagcttca gaatatccag
    25081 cagactttcc agcggcttat cttccggata gctgtcctgc cagagcgccc atgtatccgc
    25141 acgggcaaac gtacactgca caaaatcgat atgttgctgg gtggtgagcg gcattaattt
    25201 cagcccaact tcattaccca tcacgcgcgc cacctgggtc gggaagacgt attcctgctg
    25261 accgcgttta agcaacagat tcactttctg cccttccaga atctgcgcct gaccgttgat
    25321 cttgatcccc aaaccaccgt cggagaaatc ctgaacggta cacgagaaga ggtgaccatc
    25381 ttcgcgggca attgccgcgg gcatcgtcat ctccacgcgg tgcgatcggc gtacctgttt
    25441 gctttctacc gataccgcaa ctgcgccgcc aagaacaatc aggttgtaga atacccacac
    25501 catactgacg accacggtga gcatctcggt tggcgggcca tagaagtagc gccagatgcc
    25561 taccgcaacg cccaccaggt tgagcagaac aaggaagatg tagggccgcg agatcaccca
    25621 gtcgacgtac tcttcttcca ccagtccacc tttggcggtg acgttaaatt tgcctttgtg
    25681 cgggttaatc agcgccacca gcgtcggtgg tgcgatatac cacgccagca ccgtttcgta
    25741 gatttcactc cagaaagagt ggcgatattt gccctggatc ttcgagttgg tcaggctggc
    25801 atgaatcata tgcggcagca cgaacagggc gatcatcaac gctggcgcat agatgatgta
    25861 ggcatgcagc agcaggaacg ccagcggcgc agtcaggaag atcagtcgtg gaatgcccga
    25921 caagaagtgg aacatggcgt tgacatagca cagccgctga gcaaacttca gccctttacc
    25981 ggtgagcggg ttatcgagac ggaagatttg caccatcccg cgcgcccagc gaatacgctg
    26041 accgatatgc gccgacagac tttcggtcgc cagccccgcc gcctgcggaa tacgcatata
    26101 tgcagaggtg tagccacgac ggtgcaaacg cagagaagta tgcgcatctt cggttaccgt
    26161 ttcgacagca atgccgccaa tctcatccag cggcttacgg cgaatcaccg cacatgaacc
    26221 gcagaagaag gtggcgtccc acatatcgtt gccatcctgc accagaccat agaacagcgt
    26281 accttcgttc ggtgttttac ggaaacgtcc caggttgcgt tcaaacgggt ccggtgagaa
    26341 gaagtggtgc ggcgtctgca tcatcgccag ttgtttttct ttcaggaacc agcccatggt
    26401 catttgcagg aacgatcgcg ttggtacgtg gtcgcagtcg aaaatcgaca cgaactcgcc
    26461 tttggcatat ttcagcgcat tgttgatgtt gcccgctttc gcatgttcat gagtggtacg
    26521 ggcgatatat ttcaccccca cgttttgcgc aaactggcga aactcttccc tgccgccgtc
    26581 atcaaggatc caaatgttca gcttgtcttt cggccagtcg atacccagcg aggcgtaaat
    26641 cgtatttttc accacgttga gatcttcgtt gtaagtcggg acaaagatat ccaccgacgg
    26701 ccacagcgac atatctttcg gcaatggcac cggctgacga ttcagcggcc ataccacctg
    26761 gaagtaaccg agcaccagca caatccacgc gtacgtttcg gcgaacagca gaataagccc
    26821 gcacaccagg ctgaccggat cgtcccagtt cagcgtagag gtgtagcgcc accagatata
    26881 acggcaagaa acggtcagcg acagcacaat caacattagc gccgagaagc gccccggcat
    26941 ccgccgtacg atcagcgcta caccccacag cagcatcagg aagataaact gcgccagcgg
    27001 gttaaacggc tgggtaacgc agattaacgc cagaatcagc gagaaggtga cgatgatacc
    27061 gaggatcaac cgccgcgccc cggcgctcaa atggccgagt tcttttttct catcgagatg
    27121 ctgtgtttta tggctaacgc gctcaggcag ctcgttcatc cattgatggt aacgtccacg
    27181 aatattctgc agacctgaaa atgtccgcct gcgcggtttc ggcgtttctt tgcgcgatgt
    27241 accgatcagt aaccagcatg tttgaatgag ataacggacc gggtccagcg gacgcggacg
    27301 cgaggcgttg atatgcggat acaggttttt atgttctgcg cgaatacgct gccagcgcgg
    27361 gtgctccagc ggaataaaaa tccaggccag gatcaaccaa aaacagccga gcgtcgcgct
    27421 gaaagccgac gcaccgtgac gacgataatc gcgataacgc ccgataagcc gcgcgttgac
    27481 cggcgggata agcaaccacc gggtcaggat actcatgatg cactcccgac tggcgttttc
    27541 agcccggaat agttcaacag gcaccagtta gccagcgtca gtatctcttc agccgccagc
    27601 gcatcactgc ggtattcacc gactggttgc ttagccgcca ggcattgagc catcgcttca
    27661 tcacgatgaa tgagtattgg cagtaatcgg cgctggcttt gcaaccaaag ctggtaaata
    27721 tcgtcctgaa cctgactgcc gatacggaag tcattaatca aaatatgcgc gccatccggc
    27781 agcgcttgct gatgcagtcg gatatggcag ttggcatcca cattgacgat tgccagcgag
    27841 tgatcgcaca aactcagcag ctggtgggtt atctgtgagg catcacgcgg taagtcaatt
    27901 aaaatccact ggtaacgccc gctggctttt agttgctgta agccggagca aatatcgctc
    27961 agccgggttt gccagtgctg tggattttct tgttcttcaa tggataactg accaaaaggc
    28021 agcaaatcga gctgcgaggt atagcgcaac ccggcgtcac gccagtcctg gccatccagc
    28081 atagctctgg cccagccctg acggtgggta aaatcaacgt taaatgacag gcgcaacaag
    28141 ttgtccgggc aggcatcgac caccaggaca ttttctccca acatttgtaa tgaccaggct
    28201 aatgcggcgg tgatggttgt tgtccccacg cctccccgca ccccctgcaa tcccagtacg
    28261 gccattcacc aatcccctac ttttgttgcg caaactctgc cagcaacggc cagcgtttta
    28321 atgccgcggc caactgttcg cgttgggaaa tatcggcata atcaatatca ggcagtgaaa
    28381 atgcctgctt taacgccaaa atatcattct ggaagatata gcctatcgcg ggatcaggca
    28441 gagtatctgg ttcattgtta ttcatttgct tgatccctat gaaataaccg taccgttcat
    28501 gagacaattc taactgtgag catttcgccg gtttattgtt tacggcgaga cgggaatgtg
    28561 ctcacttttt gactttccgt tacgcaacag aaaaagttaa aaacgaaaag actaaaatca
    28621 catgtcttgt gacctgctaa attgattcac atgctaaatc tgataagttt taatttcaat
    28681 ggtaggttta tttcttagct ttcgctagta aactgataat cagacaaaat gttgacatga
    28741 gggacattgt ggaccctgta ttctctatcg gtatctcatc attatgggat gagctgcgac
    28801 atatgccagc aggcggcgtc tggtggttta acgtcgatcg ccatgaagat gctatcagtc
    28861 tggcgaatca aacaattgca tcccaggctg aaaccgcaca cgtcgcggtc attagcatgg
    28921 acagcgatcc agcgaaaatc tttcaattag atgattctca agggccggga aaaataacat
    28981 tattttcaat gctaaatcat gaaaaaggtc tatactattt ggcccgtgat ttgcagtgtt
    29041 ctattgatcc ccataattac ctttttattc ttgtttgcgc aaataacgca tggcaaaaca
    29101 ttcctgccga gcggcttcgc tcatggttgg ataaaatgaa taaatggagc cggctaaacc
    29161 attgttcgct tttggtaatt aattccggaa ataataacga taaacaattt tcattgttac
    29221 ttgaggaata ccgttcactt tttggtcttg ccagtttgcg ttttcagggc gaccaacatt
    29281 tgctggatat tgctttctgg tgcaacgaaa aaggggtcag cgcccgtcag cagcttagcg
    29341 ttcagcaaca aaatggttgc tggacattag ttcaacacca agaggcggaa atccaaccac
    29401 gcagcgacga aaaacgcatt ctgagtaatg tttctgtact tgaaggtgcg ccgccgctat
    29461 cggaacactg gcaactgttc aacaataacg aagtcctgtt taatgaagcc cgtaccgctc
    29521 aggcggcgac ggtggtcttt tctttacaac aaaatgcgca aatcgagcca ctggcccgca
    29581 gcattcatac tctgcgtcgc cagcgcggta gtgcgatgaa aatcctcgta cgggaaaata
    29641 ccgctagcct gcgcgccacc gatgaacgtt tgttattggc ctgcggtgca aatatggtta
    29701 tcccatggaa tgccccactc tcccgctgtc tgacgatgat cgaaagcgtg caagggcaga
    29761 agtttagtcg ctatgtgccg gaagatatca ctaccttgct gtcaatgacc cagccgctca
    29821 aactgcgtgg tttccagaag tgggatgtgt tctgtaatgc cgtcaacaac atgatgaata
    29881 accctctatt acctgcccac ggtaaaggcg ttctggttgc cctacgtccg gtaccgggta
    29941 tccgcgttga gcaagccctg acgctatgtc gccctaatcg caccggcgat atcatgacca
    30001 ttggcggtaa tcggctggtg ctgtttctct cattctgtcg gattaacgat ctggataccg
    30061 cgttgaatca tattttccca ttgcctactg gcgacatttt ctcaaaccgt atggtctggt
    30121 ttgaagatga tcaaatcagt gccgagctgg tgcagatgcg cctgcttgcc ccagaacaat
    30181 ggggcatgcc gctgccttta acgcaaagtt ctaaaccggt catcaatgcc gagcacgatg
    30241 gtcgccactg gcgacgaata ccagaaccaa tgcgactgtt agatgatgct gtggagcgct
    30301 catcatgatg accatcagcg atatcattga aattattgtc gtttgcgcac tgatattttt
    30361 cccgctgggc tatctggcgc ggcactcttt gcgacgcatt cgcgacacct tacgtttgtt
    30421 ctttgctaaa cctcgttatg ttaaaccggc cgggacgtta cgccgcacgg aaaaagccag
    30481 ggcaaccaaa aaatgactca atttacgcaa aataccgcca tgccttcttc cctctggcaa
    30541 tactggcgcg gcctttccgg ctggaacttc tattttctgg ttaagttcgg cctgttgtgg
    30601 gcgggatatc ttaacttcca tccgctcctc aatctggtgt ttgccgcgtt tctgctgatg
    30661 cccattccgc gctacagcct gcatcgctta cgccactgga ttgccctgcc gatcggcttt
    30721 gctttgttct ggcatgacac ctggttgcct ggcccggaaa gcataatgag ccagggttcg
    30781 caggtggcgg ggttcagtac cgattattta atcgaccttg tcacacgctt tattaactgg
    30841 cagatgattg gggccatttt tgttttatta gtggcctggt tattcctgtc acaatggatt
    30901 cgcattaccg tttttgtggt tgccattctg ctatggctga acgtacttac cctggcggga
    30961 ccaagtttct ccttgtggcc agccggtcaa ccaacgacca ctgtaacaac gacgggtggt
    31021 aacgcagcgg caaccgttgc ggcgacgggt ggcgcaccgg tagtgggtga tatgcccgca
    31081 caaactgcac cgccaacaac ggcgaacctt aacgcctggc tgaataattt ctataacgcg
    31141 gaggcgaaac gtaaatcaat cttcccgtct tcgctgcccg ctgatgctca gccatttgaa
    31201 ctactggtga ttaatatctg ttcgctttcc tggtcggata ttgaagccgc cgggttgatg
    31261 tcgcatccgc tgtggtcgca tttcgatatt gagttcaaga actttaactc cgccacctcc
    31321 tacagtggcc cggcggcgat ccgtttactg cgcgccagct gcgggcagac ttcgcacact
    31381 aatctgtatc aaccggcaaa taacgactgc tatctgtttg ataacctgtc gaaactgggc
    31441 tttacccagc acctgatgat gggacataac ggccagttcg gcggtttttt gaaagaagtt
    31501 cgcgaaaatg gcggcatgca gaccgaattg atggatcaaa caaatctgcc ggttgttttg
    31561 ctgggctttg atggttcgcc ggtttatgac gataccgccg tgcttaaccg ctggctggac
    31621 gttaccgaaa aagataaaaa cagccgtagt gccacgttct acaacacgct tccactgcat
    31681 gacggcaacc attatccggg cgtcagcaaa acagcggatt acaaagcgag ggcgcagaaa
    31741 ttctttgatg aactggacgc cttctttact gaactggaga aatcgggtcg taaagtgatg
    31801 gtggtcgtgg tgccagaaca cggcggcgcg ctgaagggcg acagaatgca ggtatctggc
    31861 ctacgtgata tccctagccc gtctatcaca gacgtccccg ttggggtgaa attcttcggc
    31921 atgaaggcac cacatcaggg ggcaccgatt gtcatcgacc aaccgagcag cttcctggct
    31981 atctccgatc tggtggttcg cgttcttgat ggcaagattt tctccgaaga caatgttgac
    32041 tggaaaaaac tcaccagtgg gttgccacaa acagcaccgg tctccgagaa ctcaaatgca
    32101 gtagttattc aataccagga taaaccgtac gttcgcctga acggcggcga ctgggtgcct
    32161 tacccgcaat aagaacgaaa aaggccgcag agtttccccc tgcggcctga tccgggcgca
    32221 aattgccatt acggcagcct gacgcccgca tgacacgtta cttccgctta ttcagc
//
LOCUS       DADXDL010000056        32147 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.056, whole genome shotgun sequence.
ACCESSION   DADXDL010000056 DADXDL010000000
VERSION     DADXDL010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 32147)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32147)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32147
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.056"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(62..1822)
                     /locus_tag="IRB70_002901"
     CDS             complement(62..1822)
                     /locus_tag="IRB70_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415425.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaO-like family protein"
                     /protein_id="HBC0632789.1"
                     /translation="MTQTFIPGKDAALEDSIARFQQKLSDLGFQIEEASWLNPVPNVW
                     SVHIRDKECALCFTNGKGATKKAALASALGEYFERLSTNYFFADFWLGETIANGPFVH
                     YPNEKWFPLTENDDVPEGLLDDRLRAFYDPENELTGSMLIDLQSGNEDRGICGLPFTR
                     QSDNQTIYIPMNIIGNLYVSNGMSAGNTRNEARVQGLSEVFERYVKNRIIAESISLPE
                     IPADVLARYPAVVEAIETLEAEGFPIFAYDGSLGGQYPVICVVLFNPANGTCFASFGA
                     HPDFGVALERTVTELLQGRGLKDLDVFTPPTFDDEEVAEHTNLETHFIDSSGLISWDL
                     FKQDADYPFVDWNFSGTTEEEFATLMAIFNKEDKEVYIADYEHLGVYACRIIVPGMSD
                     IYPAEDLWLANNSMGSHLRETILSLPGSEWEKEDYLNLIEQLDEEGFDDFTRVRELLG
                     LATGSDNGWYTLRIGELKAMLALAGGDLEQALVWTEWTMEFNSSVFSPERANYYRCLQ
                     TLLLLAQEEDRQPLQYLNAFVRMYGADAVEAASAAMSGEAAFYGLQPVDSDLHAFAAH
                     QSLLKAYEKLQRAKAAFWAK"
     gene            1952..2644
                     /locus_tag="IRB70_002902"
     CDS             1952..2644
                     /locus_tag="IRB70_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBC0632790.1"
                     /translation="MKAFDLHRMAFDKVPFDFLGEVALRSLYTFVLVFLFLKMTGRRG
                     VRQMSLFEVLIILTLGSAAGDVAFYDDVPMVPVLIVFITLALLYRLVMWLMAHSEKLE
                     DLLEGKPVVIIEDGELAWSKLNNSNMTEFEFFMELRLRGVEQLGQVRLAILETNGQIS
                     VYFFEDDKVKPGLLILPSDCTQRYKVVPESADYACIRCSEIIHLNAGEKQLCPRCANP
                     EWTKASRAKRVT"
     gene            2843..3931
                     /gene="serC"
                     /locus_tag="IRB70_002903"
     CDS             2843..3931
                     /gene="serC"
                     /locus_tag="IRB70_002903"
                     /EC_number="2.6.1.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoserine/phosphohydroxythreonine
                     transaminase"
                     /protein_id="HBC0632791.1"
                     /translation="MAQIFNFSSGPAMLPAEVLKQAQQELRDWNGLGTSVMEVSHRGK
                     EFIQVAEEAEKDFRDLLNIPSNYKVLFCHGGGRGQFAAVPLNILGDKTTADYVDAGYW
                     AASAIKEAKKYCTPNVFDAKVTVDGLRAVKPMREWQLSDNAAYMHYCPNETIDGIAID
                     ETPDFGKDVVVAADFSSTILSRPIDVSRYGVIYAGAQKNIGPAGLTIVIVREDLLGKA
                     NIACPSILDYSILNDNDSMFNTPPTFAWYLSGLVFKWLKANGGVVAMDKINQQKAELL
                     YGVIDNSDFYRNDVAKANRSRMNVPFQLADSALDKLFLEESFAAGLHALKGHRVVGGM
                     RASIYNAMPLEGVKALTDFMVEFERRHG"
     gene            4002..5285
                     /gene="aroA"
                     /locus_tag="IRB70_002904"
     CDS             4002..5285
                     /gene="aroA"
                     /locus_tag="IRB70_002904"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBC0632792.1"
                     /translation="MESLTLQPIARVDGTINLPGSKSVSNRALLLAALAHGKTVLTNL
                     LDSDDVRHMLNALTALGVNYTLSADRTRCEIIGNGGPLHAESARELFLGNAGTAMRPL
                     AAALCLGSNDIVLTGEPRMKERPIGHLVDALRQGGAKITYLEQENYPPLRLQGGFTGG
                     NVDVDGSVSSQFLTALLMTAPLAPEDTVIRIKGDLVSKPYIDITLNLMKTFGVEIENQ
                     HYQQFVVKGGQSYQSPGTYLVEGDASSASYFLAAAAIRGGTVKVTGIGRNSMQGDIRF
                     ADVLEKMGATICWGDDYISCTRGELNAIDMDMNHIPDAAMTIATAALFAKGTTTLRNI
                     YNWRVKETDRLFAMATELRKVGAEVEEGHDYIRITPPEKLNFAEIATYNDHRMAMCFS
                     LVALSDTPVTILDPKCTAKTFPDYFEQLARISQAA"
     gene            5454..6218
                     /gene="ycaL"
                     /locus_tag="IRB70_002905"
     CDS             5454..6218
                     /gene="ycaL"
                     /locus_tag="IRB70_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706828.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallopeptidase YcaL"
                     /protein_id="HBC0632793.1"
                     /translation="MKNTKLLLAIAASAALLTGCQNTHGIDTNMAISSGLNAYKAATL
                     SDADAKAIANQGCAEMDSGNQVASKSSKYGKRLAKIAKALGNNINGTPVNYKVYMTSD
                     VNAWAMANGCVRVYSGLMDMMNDNEIEGVLGHELGHVALGHSLAEMKASYAIVAARDA
                     ISATSGVASQLSRSQLGDIAEGAINAKYSRDKESEADDFSFDLLKKRGISTQGLVGSF
                     EKLASLDGGRTQSMFDSHPPSTERAQHIRDRIASGK"
     gene            6391..7074
                     /gene="cmk"
                     /locus_tag="IRB70_002906"
     CDS             6391..7074
                     /gene="cmk"
                     /locus_tag="IRB70_002906"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBC0632794.1"
                     /translation="MTAIAPVITIDGPSGAGKGTLCKAMAEALQWHLLDSGAIYRVLA
                     LAALHHHVDVASEDALVPLASHLDVRFVSTNGNLEVILEGEDVSGEIRTQEVANAASQ
                     VAAFPRVREALLRRQRAFRELPGLIADGRDMGTVVFPDAPVKIFLDASSEERAHRRML
                     QLQEKGFSVNFERLLAEIKERDDRDRNRAVAPLVPAADALVLDSTTLSIEQVIEKALQ
                     YARQKLALA"
     gene            7185..8858
                     /gene="rpsA"
                     /locus_tag="IRB70_002907"
     CDS             7185..8858
                     /gene="rpsA"
                     /locus_tag="IRB70_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBC0632795.1"
                     /translation="MTESFAQLFEESLKEIETRPGSIVRGVVVAIDKDVVLVDAGLKS
                     ESAIPAEQFKNAQGELEIQVGDEVDVALDAVEDGFGETLLSREKAKRHEAWITLEKAY
                     EDAETVTGVINGKVKGGFTVELNGIRAFLPGSLVDVRPVRDTLHLEGKELEFKVIKLD
                     QKRNNVVVSRRAVIESENSAERDQLLENLQEGMEVKGIVKNLTDYGAFVDLGGVDGLL
                     HITDMAWKRVKHPSEIVNVGDEITVKVLKFDRERTRVSLGLKQLGEDPWVAIAKRYPE
                     GTKLTGRVTNLTDYGCFVEIEEGVEGLVHVSEMDWTNKNIHPSKVVNVGDVVEVMVLD
                     IDEERRRISLGLKQCKANPWQQFAETHNKGDRVEGKIKSITDFGIFIGLDGGIDGLVH
                     LSDISWNVAGEEAVREYKKGDEIAAVVLQVDAERERISLGVKQLAEDPFNNWVALNKK
                     GAIVTGKVTAVDAKGATVELADGVEGYLRASEASRDRVEDATLVLSVGDEVEAKFTGV
                     DRKNRAISLSVRAKDEADEKDAIATVNKQEDANFSNNAMAEAFKAAKGE"
     gene            9018..9302
                     /gene="ihfB"
                     /locus_tag="IRB70_002908"
     CDS             9018..9302
                     /gene="ihfB"
                     /locus_tag="IRB70_002908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006819309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit beta"
                     /protein_id="HBC0632796.1"
                     /translation="MTKSELIERLATQQSHIPAKTVEDAVKEMLEHMASTLAQGERIE
                     IRGFGSFSLHYRAPRTGRNPKTGDKVELEGKYVPHFKPGKELRDRANIYG"
     gene            9508..11772
                     /locus_tag="IRB70_002909"
     CDS             9508..11772
                     /locus_tag="IRB70_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309023.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComEC family protein"
                     /protein_id="HBC0632797.1"
                     /translation="MKITTVGVCIICGIFPLLILPQLPGTVTLAFLTLFACVLAFIPV
                     KTVRYIALTLLFFLWGISAAKQILWAGETLTGATQDAIVEITATDGMTTHYGQITHLQ
                     SRRIFPAPGLVLYGEYLPQAVCAGQVWSMKLKVRAVHGQLNDGGFDSQRYAIAQHQPL
                     TGRFLQASVIEPNCSLRAQYLASLQTTLQPYPWNAVILGLGMGERLSVPKEIKNIMRD
                     TGTAHLMAISGLHIAFAALLAAGLIRSGQIFLPGRWIHWQMPLIGGICCAAFYAWLTG
                     MQPPALRTVVALAMWGMLKLSGRQWSGWDVWICCLAAILLMDPVAILSQSLWLSAAAV
                     AALIFWYQWFPCPEWQLPPVLRAVVALIHLQLGITLLLMPVQIVVFHGISLTSFIANL
                     FAIPLVTFITVPLILAAMVMHLSGPLIVEQGVWFLADRSLALLFWGLKSLPEGWINIA
                     ERWQWLSFSPWFLLVVWRLNAWRTLPAMCVAGGLLMCWPLWQKPRPDEWQVYMLDVGQ
                     GLAMVIARNGKAILYDTGLAWPEGDSGQQLIIPWLHWHNLEPEGVILSHEHLDHRGGL
                     DSILHTWPMLWIRSPLNWEHHQPCVRGEAWQWQGLRFSAHWPLQGSNDKGNNHSCVVK
                     VDDGTNSILLTGDIEAPAEQKMLSRYWQQMQATLLQVPHHGSNTSSSLPLIQRVNGKV
                     ALASASRYNAWRLPSSKVKHRYQQQGYKWLDTPHQGQITVNFSAQGWRISSLREQILP
                     RWYHQWFGVPVDNG"
     gene            11809..13557
                     /gene="msbA"
                     /locus_tag="IRB70_002910"
     CDS             11809..13557
                     /gene="msbA"
                     /locus_tag="IRB70_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid A ABC transporter ATP-binding
                     protein/permease MsbA"
                     /protein_id="HBC0632798.1"
                     /translation="MHNDKDLSTWQTFRRLWPTIAPFKAGLIVAGVALILNAASDTFM
                     LSLLKPLLDDGFGKTDRSVLVWMPLVVIGLMILRGITSYVSSYCISWVSGKVVMTMRR
                     RLFGHMMGMPVSFFDKQSTGTLLSRITYDSEQVASSSSGALITVVREGASIIGLFIMM
                     FYYSWQLSIILIVLAPIVSIAIRVVSKRFRNISKNMQNTMGQVTTSAEQMLKGHKEVL
                     IFGGQEVETKRFDKVSNRMRLQGMKMVSASSISDPIIQLIASLALAFVLYAASFPSVM
                     DSLTAGTITVVFSSMIALMRPLKSLTNVNAQFQRGMAACQTLFTILDSEQEKDEGKRV
                     IERATGDVEFRNVTFTYPGRDVPALRNINLKIPAGKTVALVGRSGSGKSTIASLITRF
                     YDIDEGEILMDGHDLREYTLASLRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQI
                     EEAARMAYAMDFINKMDNGLDTVIGENGVLLSGGQRQRIAIARALLRDSPILILDEAT
                     SALDTESERAIQAALDELQKNRTSLVIAHRLSTIEKADEIVVVEDGVIVERGTHNDLL
                     EHRGVYAQLHKMQFGQ"
     gene            13554..14540
                     /gene="lpxK"
                     /locus_tag="IRB70_002911"
     CDS             13554..14540
                     /gene="lpxK"
                     /locus_tag="IRB70_002911"
                     /EC_number="2.7.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetraacyldisaccharide 4'-kinase"
                     /protein_id="HBC0632799.1"
                     /translation="MIEKIWSGESPLWRLLLPLSWLYGLVSGAIRLCYKLKLKRAWRA
                     PVPVVVVGNLTAGGNGKTPVVVWLVEQLQQRGIRVGVVSRGYGGKAESYPLLLSADTT
                     TAQAGDEPVLIYQRTDAPVAVSPVRSDAIKAILAQHPDVQIIVTDDGLQHYRLARDVE
                     IVVIDGVRRFGNGWWLPAGPMRERAGRLKSVDAVIVNGGVPRSGEIPMHLLPGQAVNL
                     RTGTRCDVTQLEHVVAMAGIGHPPRFFATLKMCGVQPEKCVPLADHQSLNHADVSALV
                     NAGQTLVMTEKDAVKCRAFAEENWWYLPVDAQLSGDEPAKLLAQLTSLASGN"
     gene            14577..15809
                     /locus_tag="IRB70_002912"
     CDS             14577..15809
                     /locus_tag="IRB70_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcaQ family DNA glycosylase"
                     /protein_id="HBC0632800.1"
                     /translation="MSLPHLSLADARNLHLAAQGLLNKPRRRASLEDIPATISRMSLL
                     QIDTINIVARSPYLVLFSRLGNYPAQWLDESLARGELMEYWAHEACFMPRSDFRLIRH
                     RMLAPEKMGWKYKDAWMQEHAAEIALLIQHIHDKGPVRSADFEHPRKGASGWWEWKPH
                     KRHLEGLFTAGKVMVIERRNFQRVYDLTHRVMPDWDDERDLVSQAEAEIIMLDNSARS
                     LGIFREQWLADYYRLKRPALAAWREARAEQQQIIAVHVEKLGNLWLHADLLPLLERAL
                     AGKLTATHSAVLSPFDPVVWDRKRAEQLFDFSYRLECYTPAPKRQYGYFVLPLLHRGQ
                     LVGRMDAKMHRQTGILEVISLWLQEGIKPTTTLQKGLRQAITDFANWQQATRVTLGRC
                     PQGLFTDCRTGWEIDPVA"
     gene            15861..16043
                     /gene="ycaR"
                     /locus_tag="IRB70_002913"
     CDS             15861..16043
                     /gene="ycaR"
                     /locus_tag="IRB70_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YcaR"
                     /protein_id="HBC0632801.1"
                     /translation="MDHRLLEIIACPVCNGKLWYNQEKQELICKLDNLAFPLRDGIPV
                     LLETEARVLTADESKS"
     gene            16040..16786
                     /gene="kdsB"
                     /locus_tag="IRB70_002914"
     CDS             16040..16786
                     /gene="kdsB"
                     /locus_tag="IRB70_002914"
                     /EC_number="2.7.7.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-manno-octulosonate cytidylyltransferase"
                     /protein_id="HBC0632802.1"
                     /translation="MSFVVIIPARYASTRLPGKPLVDINGKPMIVHVLERARESGAER
                     IIVATDHEDVARAVEAAGGEVCMTRADHQSGTERLAEVVEKCAFSDDTVIVNVQGDEP
                     MIPATIIRQVADNLAQRQVGMATLAVPIHNAEEAFNPNAVKVVLDAEGYALYFSRATI
                     PWDRDRFAKDLETVGDNFLRHLGIYGYRAGFIRRYVTWQPSPLEHIEMLEQLRVLWYG
                     EKIHVAVAREVPGTGVDTPEDLERVRAEMR"
     gene            16940..17833
                     /locus_tag="IRB70_002915"
     CDS             16940..17833
                     /locus_tag="IRB70_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbJ family phosphotransferase"
                     /protein_id="HBC0632803.1"
                     /translation="MEQLRAELSHLLGEKLSRIECVNEKADTALWALYDSQGNPMPLM
                     ARSFSTPGKARQLAWKTTMLARSGTVRMPTIYGVMTHEEHPGPDVLLLERMRGVSVEA
                     PARTPERWEQLKDQIVEALLAWHRQDSRGCVGAVDNTQENFWPSWYRQHVEVLWTTLN
                     QFNNTGLTMQDKRILFRTRECLPALFEGFNDNCVLIHGNFCLRSMLKDSRSDQLLAMV
                     GPGLMLWAPREYELFRLMDNSLAEDLLWSYLQRAPVAESFIWRRWLYVLWDEVAQLVN
                     TGRFSRRNFDLASKSLLPWLA"
     gene            complement(17810..18589)
                     /gene="elyC"
                     /locus_tag="IRB70_002916"
     CDS             complement(17810..18589)
                     /gene="elyC"
                     /locus_tag="IRB70_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope biogenesis factor ElyC"
                     /protein_id="HBC0632804.1"
                     /translation="MLFTLKKVIGGMLLPLPLMLLIIGAGLALLWFSRFQKTGKIFIS
                     IGWLALLLLSLQPVADRLLRPIESTYPTWNNSQKVDYIVVLGGGYTWNPQWAPSSNLI
                     NNSLPRLNEGIRLWRENPGSKLIFTGGVAKTNTVSTAEVGARVAQSLGVPREQIITLD
                     LPKDTEEEAAAVKQAIGDAPFLLVTSASHLPRAMIFFQQEGLNPLPAPANQLAIDSPL
                     NPWERAIPSPVWLMHSDRVGYETLGRIWQWLKGSSGEPRQE"
     gene            18725..19510
                     /gene="cmoM"
                     /locus_tag="IRB70_002917"
     CDS             18725..19510
                     /gene="cmoM"
                     /locus_tag="IRB70_002917"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine 5-oxyacetic acid(34)
                     methyltransferase CmoM"
                     /protein_id="HBC0632805.1"
                     /translation="MQDRNFDDIAEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQ
                     KLRVLDAGGGEGQTAIKMAEHGHQVILCDLSAQMIDRAKQAAEAKGVSDNMQFIHCAA
                     QDVASHLETPVDLILFHAVLEWVADPRSVLQTLWSVLRPGGVLSLMFYNAHGLLMHNM
                     VAGNFDYVQAGMPKKKKRTLSPDYPRDPAQVYLWLEEAGWQIMGKTGVRVFHDYLREK
                     HQQRDCYEALLELETRYCRQEPYITLGRYIHVTARKPQSKDKV"
     gene            19507..20829
                     /gene="mukF"
                     /locus_tag="IRB70_002918"
     CDS             19507..20829
                     /gene="mukF"
                     /locus_tag="IRB70_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukF"
                     /protein_id="HBC0632806.1"
                     /translation="MSEFSQTVPELVAWARKNDFSISLPVDRLSFLLAVATLNGERLD
                     GEMSEGELVDAFRHVSDAFEQTSETIGVRANNAINDMVRQRLLNRFTSEQAEGNAIYR
                     LTPLGIGITDYYIRQREFSTLRLSMQLSIVAGELKRAADAAEEGGDEFHWHRNVYAPL
                     KYSVAEIFDSIDLTQRLMDEQQQQVKDDIAQLLNKDWRAAISSCELLLSETSGTLREL
                     QDTLEAAGDKLQANLLRIQDATMTHDDLHFVDRLVFDLQSKLDRIISWGQQSIDLWIG
                     YDRHVHKFIRTAIDMDKNRVFAQRLRQSVQTYFDEPWALTYANADRLLDMRDEEMALR
                     DEEVTGELPEDLEYEEFNEIREQLAAIIEEQLAVYKTRQVPLDLGLVVREYLSQYPRA
                     RHFDVARIVIDQAVRLGVAQADFTGLPAKWQPINDYGAKVQAHVIDKY"
     gene            20810..21514
                     /gene="mukE"
                     /locus_tag="IRB70_002919"
     CDS             20810..21514
                     /gene="mukE"
                     /locus_tag="IRB70_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415443.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukE"
                     /protein_id="HBC0632807.1"
                     /translation="MSSTNIEQVMPVKLAQALANPLFPALDSALRSGRHIGLDELDNH
                     AFLMDFQEYLEEFYARYNVELIRAPEGFFYLRPRSTTLIPRSVLSELDMMVGKILCYL
                     YLSPERLANEGIFTQQELYDELLTLADEAKLLKLVNNRSTGSDVDRQKLQEKVRSSLN
                     RLRRLGMVWFMGHDSSKFRITESVFRFGADVRAGDDPREAQRRLIRDGEAMPIENHLQ
                     LNDETEENQPDSGEEE"
     gene            21514..25974
                     /gene="mukB"
                     /locus_tag="IRB70_002920"
     CDS             21514..25974
                     /gene="mukB"
                     /locus_tag="IRB70_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome partition protein MukB"
                     /protein_id="HBC0632808.1"
                     /translation="MIERGKFRSLTLINWNGFFARTFDLDELVTTLSGGNGAGKSTTM
                     AAFVTALIPDLTLLHFRNTTEAGATSGSRDKGLHGKLKAGVCYSMLDTINSRHQRVVV
                     GVRLQQVAGRDRKVDIKPFAIQGLPMSVQPTQLVTETLSERQARVLPLNELKDKLEAM
                     EGVQFKQFNSITDYHSLMFDLGIIARRLRSASDRSKFYRLIEASLYGGISSAITRSLR
                     DYLLPENSGVRKAFQDMEAALRENRMTLEAIRVTQSDRDLFKHLISEATNYVAADYMR
                     HANERRVHLDKALEFRRELHTSRQQLAAEQYKHVDMARELAEHNGAEGDLEADYQAAS
                     DHLNLVQTALRQQEKIERYEADLDELQIRLEEQNEVVAEAIERQEENEARAEAAELEV
                     DELKSQLADYQQALDVQQTRAIQYNQAIAALNRAKELCHLPDLTADSAAEWLETFQAK
                     ELEATEKMLSLEQKMSMAQTAHSQFEQAYQLVVAINGPLARNEAWDVARELLREGVDQ
                     RHLAEQVQPLRMRLSELEQRLREQQEAERLLADFCKRQGKNFDIDELEALHQELEARI
                     ASLSDSVSNAREERMALRQEQEQLQSRIQSLMQRAPVWLAAQNSLNQLSEQCGEEFSS
                     SQDVTEYLQQLLEREREAIVERDEVGARKNAVDEEIERLSQPGGSEDQRLNALAERFG
                     GVLLSEIYDDVSLEDAPYFSALYGPSRHAIVVPDLSQVTEHLEGLTDCPEDLYLIEGD
                     PQSFDDSVFSVDELEKAVVVKIADRQWRYSRFPEVPLFGRAARESRIESLHAEREVLS
                     ERFATLSFDVQKTQRLHQAFSRFIGSHLAVAFESDPEAEIRQLNSRRVELERALSNHE
                     NDNQQQRIQFEQAKEGVTALNRILPRLNLLADDSLADRVDEIRERLDEAQEAARFVQQ
                     FGNQLAKLEPIVSVLQSDPEQFEQLKEDYAYSQQMQRDARQQAFALTEVVQRRAHFSY
                     SDSAEMLSGNSDLNEKLRERLEQAEAERTRAREALRGHAAQLSQYNQVLASLKSSYDT
                     KKELLNDLQRELQDIGVRADSGAEERARIRRDELHAQLSNNRSRRNQLEKALTFCEAE
                     MDNLTRKLRKLERDYFEMREQVVTAKAGWCAVMRMVKDNGVERRLHRRELAYLSADDL
                     RSMSDKALGALRLAVADNEHLRDVLRMSEDPKRPERKIQFFVAVYQHLRERIRQDIIR
                     TDDPVEAIEQMEIELSRLTEELTSREQKLAISSRSVANIIRKTIQREQNRIRMLNQGL
                     QSVSFGQVNSVRLNVNVRETHAMLLDVLSEQHEQHQDLFNSNRLTFSEALAKLYQRLN
                     PQIDMGQRTPQTIGEELLDYRNYLEMEVEVNRGSDGWLRAESGALSTGEAIGTGMSIL
                     VMVVQSWEDESRRLRGKDISPCRLLFLDEAARLDARSIATLFELCERLQMQLIIAAPE
                     NISPEKGTTYKLVRKVFQNTEHVHVVGLRGFAPQLPETLPGSDEAPSQAS"
     gene            26235..28082
                     /gene="ldtD"
                     /locus_tag="IRB70_002921"
     CDS             26235..28082
                     /gene="ldtD"
                     /locus_tag="IRB70_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HBC0632809.1"
                     /translation="MLLNMMCGRRLSAISLCLAVTFAPLFNAQADEPEVIPGDSPVAV
                     SEQGEALPQAQATAIMAGIQPLPEGAAEKARTQIESQLPAGYKPVYLNQLQLLYAARD
                     MQPMWENRDAVKAFQQQLAEVAIAGFQPQFNKWVELLTDPGVNGMARDVVLSDAMMGY
                     LHFIANIPVKGTRWLYSSKPYALSTPPLSVINQWQLALDKGQLPTFVAGLAPQHPQYA
                     AMHESLLALLSDTKPWPQLTGKATLRPGQWSNDVPALREILQRTGMLDGGPKITLPGD
                     DTPTDTVVSPSAVTVETAETKPMDKQTTSRSKPAPAVRAAYDNELVEAVKRFQAWQGL
                     GADGAIGPATRDWLNVTPAQRAGVLALNIQRLRLLPTELSTGIMVNIPAYSLVYYQNG
                     NQVLDSRVIVGRPDRKTPMMSSALNNVVVNPPWNVPPTLARKDILPKVRNDPGYLESH
                     GYTVMRGWNSREAIDPWQVDWSTITASNLPFRFQQAPGPRNSLGRYKFNMPSSEAIYL
                     HDTPNHNLFKRDTRALSSGCVRVNKASDLANMLLQDAGWNDKRISDALKQGDTRYVNI
                     RQSIPVNLYYLTAFVGADGRTQYRTDIYNYDLPARSSSQIVSKAEQLIR"
     gene            28263..28811
                     /locus_tag="IRB70_002922"
     CDS             28263..28811
                     /locus_tag="IRB70_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YcbK family protein"
                     /protein_id="HBC0632810.1"
                     /translation="MDKFDANRRKLLALGGVALGAAILPTPAFATLSTPRPRILTLNN
                     LHTGESIKAEFFDGRGYIQEELAKLNHFFRDYRANKIKSIDPGLFDQLYRLQGLLGTR
                     KPVQLISGYRSIDTNNELRARSRGVAKKSYHTKGQAMDFHIEGIALSNIRKAALSMRA
                     GGVGYYPRSNFVHIDTGPARHW"
     gene            28838..29485
                     /gene="gloC"
                     /locus_tag="IRB70_002923"
     CDS             28838..29485
                     /gene="gloC"
                     /locus_tag="IRB70_002923"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003035823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase GloC"
                     /protein_id="HBC0632811.1"
                     /translation="MNYRIIPVTAFSQNCSLIWCEQTRLAALVDPGGDAEKIKQEVDA
                     SGLTLMQILLTHGHLDHVGAAAELAQHYGVPVFGPEKEDEFWLQGLPAQSRMFGLEEC
                     QPLTPDRWLNEGDTISIGNVTLQVLHCPGHTPGHVVFFDERARLLISGDVIFKGGVGR
                     SDFPRGDHNQLISSIKDKLLPLGDDVTFIPGHGPLSTLGYERLHNPFLQDEMPVW"
     gene            complement(29535..30725)
                     /gene="aspC"
                     /locus_tag="IRB70_002924"
     CDS             complement(29535..30725)
                     /gene="aspC"
                     /locus_tag="IRB70_002924"
                     /EC_number="2.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009653304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate transaminase"
                     /protein_id="HBC0632812.1"
                     /translation="MFENITAAPADPILGLADLFRADERPGKINLGIGVYKDETGKTP
                     VLTSVKKAEQYLLENETTKNYLGIDGIPEFGRCTQELLFGKGSALINDKRARTAQTPG
                     GTGALRVAADFLAKNTSVKRVWVSNPSWPNHKSVFNSAGLEVREYAYYDAENHTLDFD
                     ALINSLNEAQAGDVVLFHGCCHNPTGIDPTLEQWQTLAQLSVEKGWLPLFDFAYQGFA
                     RGLEEDAEGLRAFAAMHKELIVASSYSKNFGLYNERVGACTLVAADSETVDRAFSQMK
                     AAIRANYSNPPAHGASVVATILSNDALRAIWEQELTDMRQRIQRMRQLFVNTLQEKGA
                     NRDFSFIIKQNGMFSFSGLTKEQVLRLREEFGVYAVASGRVNVAGMTPDNMAPLCEAI
                     VAVL"
     gene            complement(30910..31983)
                     /gene="ompF"
                     /locus_tag="IRB70_002925"
     CDS             complement(30910..31983)
                     /gene="ompF"
                     /locus_tag="IRB70_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpF"
                     /protein_id="HBC0632813.1"
                     /translation="MMKRNILAVIVPALLVAGTANAAEIYNKDGNKVDLYGKAVGLHY
                     FSKDNGVNSYGGNGDKTYARLGFKGETQINSDLTGYGQWEYNFQGNNSEGADAQKGNK
                     TRLAFAGLKFADAGSIDYGRNYGVVYDALGYTDMLPEFGGDTAYSDDFFVGRVGGVAT
                     YRNSNFFGLVDGLNFAVQYLGKNERAGIPERSNGDGVGGSISYEFEGFGIVGAYGAAD
                     RTDAQEAEFRGQGKKAEQWATGLKYDANNIYLAANYGETRNATPIEGGFANKTQDVLL
                     VAQYQFDFGLRPSIAYTKSKAKDVEGIGDVDLVNYFEVGATYYFNKNMSTYVDYIINQ
                     IDSDNKLGVGSDDTVAVGIVYQF"
BASE COUNT         7812 a         7879 c         8663 g         7793 t
ORIGIN      
        1 aaacgccccg taatataact cagacgaatc attaagccta cattgcgtag gctatttgat
       61 tttattttgc ccagaatgct gctttggcgc gctgcagctt ttcgtaggcc ttcaacaacg
      121 actgatgtgc agcaaacgcg tgcagatcgc tatctactgg ttgcaagcca taaaacgccg
      181 cttcgccgct cattgccgca ctggcggctt ccacggcatc tgcgccgtac atgcgaacaa
      241 acgcattcag atattgcagc ggctggcgat cttcttcctg cgccagtaat aacaacgttt
      301 gcaggcagcg ataatagttg gcgcgttccg gactaaatac tgatgagtta aactccatcg
      361 tccattcggt ccagaccaga gcctgttcca gatcgccacc agccagcgcc agcatggctt
      421 ttaattctcc gatacgcagg gtgtaccaac cgttatccga cccggtcgcc agacccaaca
      481 gctcacgcac gcgagtaaag tcatcaaaac cttcttcatc cagttgctcg ataaggttca
      541 ggtaatcttc tttttcccac tcgctgcctg gtaacgaaag aatcgtttca cgtaaatggc
      601 tgcccatact gttattcgcc agccacagat cttcagccgg ataaatatcg gacatgccag
      661 gcacgataat tcggcaagca taaacgccca gatgctcgta atcggcaata taaacttctt
      721 tatcttcttt gttgaagata gccatcagcg tagcaaactc ttcttccgta gtgccggaga
      781 aattccagtc cacaaacgga taatcggcat cctgcttgaa caggtcccag gagattaaac
      841 cgctggaatc gataaagtgc gtttcgaggt tggtatgttc agcaacttct tcatcatcga
      901 aggttggcgg agtaaacaca tccaaatctt tcaggccacg accttgcagc agctcggtca
      961 cggtacgttc cagtgctacg ccaaaatcag gatgcgcacc gaaagaggca aagcaggtgc
     1021 cgttagcagg attaaacaga accacgcaaa tcaccggata ctggccgcca agcgaaccat
     1081 cataagcaaa gattgggaaa ccttctgctt ccagtgtttc gatcgcttca accaccgctg
     1141 ggtaacgcgc cagcacgtct gccgggattt ccggcaagct gatgctttca gcaataatgc
     1201 ggtttttcac gtagcgttcg aaaacttcgg acaatccctg aacgcgtgct tcgttacggg
     1261 tattgccagc agacataccg ttagaaacgt acaagttacc aatgatattc atcggaatat
     1321 aaatggtctg gttgtcggac tggcgcgtaa acggtagacc gcaaatacca cgatcttcgt
     1381 taccggattg caggtcaatc agcatactac cggtcagttc attctccgga tcgtaaaatg
     1441 cgcgcagacg gtcatcgagc agcccttctg gtacatcgtc attttcggtc agtgggaacc
     1501 atttttcgtt gggataatgc acgaatgggc cgttggcgat ggtttcgccc agccagaagt
     1561 ccgcaaaaaa gtagttggtt gagagacgct cgaaatattc accgagggca gaagccagcg
     1621 ccgctttttt ggttgcgcct ttaccgttgg taaaacacag tgcgcactct ttgtcgcgaa
     1681 tatgtacaga ccagacatta ggcacgggat tcagccagga ggcctcttca atctgaaaac
     1741 cgaggtctga aagtttttgc tggaagcgtg cgatggaatc ttccagagcg gcatctttgc
     1801 cggggataaa tgtttgcgtc atgaaaatca ctttagtcgt acggaaagcg cgcaataata
     1861 cgggttttat ctcaaaggcg ctatcaccgc cgccatgccg atgaactgtt ggctatgctt
     1921 ttagcggata aaccacgata agagcataaa aatgaaggcg ttcgatctcc accgtatggc
     1981 atttgataaa gtgccttttg atttccttgg cgaagtggca ctacgtagtc tttatacctt
     2041 tgtactggtt tttttgttcc tcaaaatgac cggaagacgc ggtgtgcggc agatgtcgct
     2101 gtttgaagtg ttaatcattc tgacgctggg ttcagcggcg ggagatgtgg cgttttatga
     2161 tgatgtgccg atggtcccgg tacttatcgt ctttattact ctggcgttgt tataccgcct
     2221 ggtaatgtgg ttgatggcgc acagtgaaaa actggaagat ctactggaag gtaagccggt
     2281 tgtcattatt gaagatggcg agctggcctg gtcgaaactc aataactcca acatgacgga
     2341 atttgagttc tttatggagc tacgattgcg cggtgtggaa cagctggggc aggtacgtct
     2401 ggcgattctc gaaaccaacg ggcaaatcag tgtctatttc tttgaagatg acaaggtgaa
     2461 accggggtta cttattttac ccagtgactg tactcagcgt tacaaagtgg tgccggagtc
     2521 ggcggactat gcctgcattc gttgcagtga aatcattcat ttgaacgcgg gggaaaaaca
     2581 attatgtccg cgctgtgcaa atccagaatg gacgaaggca agtcgggcaa aacgggtgac
     2641 ctgacagtaa aaacatcggc tttttgctaa taatccgaga gattcttttg tgtgatgcaa
     2701 gccacatgtt tgccctcaac ggttttactc attgcgatgt gtgtcactga atgataaaac
     2761 cgatagccac aggaataatg tattacctgt ggtcgcaatc gattgaccgc gggttaatag
     2821 caacgcaacg tggtgagggg aaatggctca aatcttcaat tttagttctg gtccggcaat
     2881 gctaccggca gaggtgctta aacaggctca acaggaactg cgtgactgga acggtcttgg
     2941 tacgtcggtg atggaagtga gtcaccgggg caaagagttc attcaggttg cagaggaagc
     3001 cgagaaggat tttcgcgatc ttcttaacat cccctccaac tacaaagtat tgttctgcca
     3061 tggcggcggt cgcggtcagt ttgctgctgt tccgctgaat attctcggtg ataaaaccac
     3121 cgcagattat gttgatgccg gttactgggc ggcaagtgcc attaaagaag cgaaaaaata
     3181 ttgcacgcct aatgtcttcg acgccaaagt gactgttgat ggtctgcgcg cggttaagcc
     3241 aatgcgcgaa tggcaactct ctgataatgc tgcttatatg cattactgcc cgaatgaaac
     3301 catcgacggt atcgctatcg acgaaacgcc agacttcggc aaagatgtgg tggtcgccgc
     3361 cgacttctct tcaaccattc tttcccgtcc gattgacgtc agccgttatg gtgtaattta
     3421 cgctggcgcg cagaaaaata tcggcccggc tggcctgaca atcgtcatcg ttcgtgaaga
     3481 tttgctgggc aaagcgaata tcgcgtgtcc gtcgattctg gattattcca ttctcaacga
     3541 taacgattcc atgttcaaca cgccgccgac atttgcctgg tacttatctg gcctggtctt
     3601 caaatggctg aaagcgaacg gcggtgtggt tgcaatggat aaaatcaatc agcaaaaagc
     3661 agaactgcta tatggggtga ttgataacag cgatttctac cgcaatgacg tggcgaaagc
     3721 taaccgttcg cggatgaacg tgccgttcca gttggcggac agtgcgcttg acaaattgtt
     3781 ccttgaagag tcttttgctg caggccttca tgcactgaaa ggtcaccgtg tggtcggcgg
     3841 aatgcgtgcg tctatttata acgccatgcc actggaaggc gttaaagcgc tgacagactt
     3901 catggttgag ttcgaacgcc gtcacggcta atgtcgaaat tttgcataat ccccacagcc
     3961 agcctgtggg gtttttattt ctgttgtaga gagttgagtt catggaatcc ctaacgttac
     4021 aacccatcgc tcgtgtcgat ggcactatta atctgcccgg ttccaagagc gtttctaacc
     4081 gcgctttatt gctggcggca ttagcacacg gcaaaacagt attaaccaat ctgctggata
     4141 gcgatgacgt gcgccatatg ctgaatgcat taacagcgtt aggggtaaac tatacgcttt
     4201 cagccgatcg tacgcgttgc gaaattatcg gtaacggtgg gccattacac gcagaaagtg
     4261 cccgggagtt gttcctcggt aacgccggaa cggcaatgcg tccgctggcg gcagcacttt
     4321 gcctgggtag caatgatatt gtactgaccg gtgaaccgcg aatgaaagaa cgcccgattg
     4381 gtcatctggt ggatgcgctg cgccagggcg gggcgaagat cacttacctg gaacaagaaa
     4441 attatccgcc attgcgttta cagggcggct ttactggcgg caacgttgat gttgatggct
     4501 ccgtttcaag ccagttcctc accgcactgt taatgactgc acctcttgcg ccggaagata
     4561 cggtgattcg tattaaaggc gatctggttt ctaaacctta tatcgacatc accctcaatc
     4621 tgatgaagac gtttggtgtt gaaattgaaa atcagcacta tcaacaattt gtcgtaaaag
     4681 gggggcagtc ttatcagtct ccgggtactt atttggtcga aggcgatgca tcctcggctt
     4741 cttatttcct ggcagcagca gcaatcagag gcggcactgt aaaagtgacc ggcattggac
     4801 gcaacagtat gcagggtgat attcgctttg ctgatgtgct ggaaaaaatg ggtgcgacca
     4861 tttgctgggg cgatgattat atttcctgca cgcgtggtga actgaacgcc attgatatgg
     4921 atatgaacca tattcctgat gcggcgatga ccattgccac ggcggcgtta tttgcaaaag
     4981 gcaccaccac gctgcgcaat atctataact ggcgtgttaa agagaccgat cgcctgtttg
     5041 cgatggcaac agaactgcgt aaagttggtg cggaagtcga agaggggcac gattacattc
     5101 gtatcactcc tccggaaaaa ctgaactttg ccgagatcgc cacttataat gatcaccgga
     5161 tggcgatgtg tttctcgcta gtggcgttgt cagatacacc agtgacgatt cttgatccca
     5221 aatgcacggc caaaacattt ccggattatt tcgagcagct ggcgcggatt agccaggcag
     5281 cctgaatgaa caacgggcaa taaatagcca aatctttctt tatcaaaacg tcggcacatt
     5341 gtcggcgttt tttttcggac cttgtgagtc attttgatta atggtagcgt cgcttgtcaa
     5401 tgtaagttgt tgatacataa tatttatata tgattaatca acggatgatt cacatgaaga
     5461 atactaaatt actgctggcg attgcggcct ctgcagcatt actgacaggg tgtcaaaata
     5521 cccacggtat tgataccaat atggctatca gctcaggttt aaatgcctat aaagcagcaa
     5581 cgttaagcga tgctgatgca aaagcgattg ccaatcaggg ctgtgccgaa atggacagcg
     5641 gcaatcaagt cgcaagtaaa tccagcaagt acggtaaacg tctggcaaaa atcgccaaag
     5701 cattgggtaa caatattaat ggcacgccgg tcaactataa ggtttatatg accagcgacg
     5761 tcaacgcatg ggcgatggcg aacggctgtg ttcgtgtcta cagtggcctg atggacatga
     5821 tgaacgacaa cgaaattgaa ggcgttctgg gccatgaact gggccacgtc gcgttgggtc
     5881 actcgctggc tgaaatgaaa gcttcttatg cgatcgttgc cgcacgtgat gcgatttccg
     5941 ctaccagcgg tgtggcttcc cagctttctc gctcacaatt aggtgatatc gcagaaggcg
     6001 cgatcaatgc taaatactcc cgcgataaag agtccgaagc agatgatttc tcctttgatc
     6061 tgttgaagaa acgtggcatc agcacccagg ggctggttgg cagctttgaa aaattggcca
     6121 gcctggatgg cggtcgtacc cagtccatgt ttgactctca cccaccatca acagagcgtg
     6181 cgcaacacat ccgtgatcgt atcgcctctg gtaagtaaat cattgtcatc tttcgggctg
     6241 gtcttctgcc agcccgctat aattgcgcaa taaatcccca tctgaataca gacaaaactg
     6301 gtttttgcac acaacgttaa cgatttgtgg cgtcggcgcg tataatgcgc gcggttatgt
     6361 taacggtacg cctgttttaa ggagataaag atgacggcaa ttgccccggt tattaccatt
     6421 gatggcccaa gcggtgcagg gaaaggcacc ttgtgtaagg ctatggcgga agcgttgcaa
     6481 tggcatctgc tggattcggg tgcaatttat cgcgtactgg cactggcggc attacatcac
     6541 catgttgatg ttgcttcgga agatgcgctg gtgccgctgg catcccatct ggatgtacgt
     6601 tttgtgtcga ccaatggcaa tctggaagtg atcctcgaag gggaagatgt cagcggcgaa
     6661 attcgtactc aggaagtggc gaatgctgct tcacaagtcg cggcattccc acgcgttcgt
     6721 gaagcattat tgcgtcgcca acgcgcgttt cgcgaattac caggcctgat tgccgatggc
     6781 cgcgacatgg gaacggtggt attccctgat gcgccagtga aaattttcct tgacgcctcc
     6841 tcggaagaac gtgcgcatcg ccgcatgcta cagttgcagg agaagggctt tagtgttaac
     6901 tttgagcgcc ttttggccga gatcaaagaa cgcgacgacc gcgatcgtaa ccgagcggta
     6961 gcgccactgg ttccggcagc cgatgcttta gtgttggatt ccaccacctt aagcattgag
     7021 caagtgattg aaaaagcgct acaatacgcg cgccagaaat tggctctcgc ataagcgacc
     7081 gaatttgcag tacccccgtt gcaatggaat gacagcgggt atgttaaaca accccatccg
     7141 gcatggagcc aggtggacgt taaatataaa cctgaagatt aaacatgact gaatcttttg
     7201 ctcaactctt tgaagagtcc ttaaaagaaa tcgaaacccg cccgggttct atcgttcgtg
     7261 gcgttgttgt tgctatcgac aaagacgtag tactggttga cgctggtctg aaatctgagt
     7321 ccgccatccc ggctgagcag ttcaaaaacg cccagggcga gctggaaatc caggtaggtg
     7381 acgaagttga cgttgctctg gacgcagtag aagacggctt cggtgaaact ctgctgtccc
     7441 gtgagaaagc taaacgtcac gaagcttgga tcacgctgga aaaagcttac gaagatgctg
     7501 aaactgttac cggtgttatc aacggcaaag ttaagggcgg cttcactgtt gagctgaacg
     7561 gtattcgtgc gttcctgcca ggttctctgg tagacgttcg tccggtgcgt gacactctgc
     7621 acctggaagg caaagagctt gaattcaaag taatcaagct ggatcagaag cgcaacaacg
     7681 ttgttgtttc tcgtcgtgcc gttatcgaat ccgaaaacag cgcagagcgc gatcagctgc
     7741 tggaaaacct gcaggaaggc atggaagtta aaggtatcgt taagaacctc actgactacg
     7801 gtgcattcgt tgatctgggc ggcgttgacg gcctgctgca catcactgat atggcctgga
     7861 aacgcgttaa gcatccgagc gaaatcgtca acgtgggcga cgaaatcact gttaaagtgc
     7921 tgaagttcga ccgcgaacgt acccgtgtat ccctgggcct gaaacagctg ggtgaagatc
     7981 cgtgggtagc tatcgctaaa cgttatccgg aaggtaccaa actgactggt cgcgtgacca
     8041 acctgaccga ctacggctgc ttcgttgaaa tcgaagaagg cgttgaaggc ctggtacacg
     8101 tttccgaaat ggattggacc aacaaaaaca tccacccgtc caaagttgtt aacgttggcg
     8161 atgtagtgga agttatggtt ctggatatcg acgaagaacg tcgtcgtatc tccctgggtc
     8221 tgaaacagtg caaagctaac ccgtggcagc agttcgcgga aacccacaac aagggtgacc
     8281 gtgttgaagg taaaatcaag tctatcactg acttcggtat cttcatcggc ctggacggcg
     8341 gcatcgacgg cctggttcac ctgtctgaca tctcctggaa cgttgcaggc gaagaagcag
     8401 ttcgtgaata caaaaaaggc gacgaaatcg ctgcagttgt tctgcaggtt gacgcagaac
     8461 gtgaacgtat ctccctgggc gttaaacagc tcgcagaaga tccgttcaac aactgggttg
     8521 ctctgaacaa gaaaggcgct atcgtaaccg gtaaagtaac tgcagttgac gctaaaggcg
     8581 caaccgtaga actggctgac ggcgttgaag gttacctgcg tgcttctgaa gcatcccgtg
     8641 accgcgttga agacgctacc ctggttctga gcgttggcga cgaagttgaa gctaaattca
     8701 ccggcgttga tcgtaaaaac cgcgcaatca gcctgtctgt tcgtgcgaaa gacgaagctg
     8761 acgagaaaga tgcaatcgca actgttaaca aacaggaaga tgcaaacttc tccaacaacg
     8821 caatggctga agctttcaaa gcagctaaag gcgagtaatt ctctgactct tcgggatttt
     8881 tattccgaag tttgttgagt ttacttgaca gattgcaggt ttcgtcctgt aatcaagcac
     8941 taagggcggc tacggccgcc cttaatcaat gcagcaacag cagccgctta atttgccttt
     9001 aaggaaccgg aggaatcatg accaagtcag aattgataga aagacttgcc acccagcaat
     9061 cgcacattcc cgccaagacg gttgaagatg cagtaaaaga gatgctggag catatggcct
     9121 cgactcttgc gcagggcgag cgtattgaaa tccgcggttt cggcagtttc tctttgcact
     9181 accgcgcacc acgtaccgga cgtaatccga agactggcga taaagtagaa ctggaaggaa
     9241 aatacgttcc tcactttaaa ccaggtaaag aactgcgcga tcgcgccaat atttacggtt
     9301 aagtttttac tcaaacttga acgcgagaaa agcacctgtc gggtgctttt ttcatttctc
     9361 taatctggaa ctggaagctg cctcgcagag ttttgagcag ttttcaccct atcgttaaat
     9421 tcttctgaac gtgcctcggg gaacgcaaaa cacccaccag acaaccgttc aacaaagttg
     9481 cacactttct ataaacaggg agggtgcatg aaaataacga cagtcggcgt atgcataatt
     9541 tgcggaattt ttccgttgct gattttgccc caattgccag ggacagtaac ccttgcgttt
     9601 ctgactctct tcgcctgtgt actggcattt atccctgtta aaaccgtccg ttatatcgcg
     9661 ctgacgttgc tgttttttct ttggggcata tcagcggcaa agcaaatttt gtgggcagga
     9721 gaaaccttaa ctggcgcgac gcaggatgca atagttgaga tcactgctac tgacggcatg
     9781 accactcatt acggtcaaat cactcatcta caaagtcgac gtatattccc tgcgccaggc
     9841 ctcgtactgt atggcgaata tcttccgcaa gcggtttgtg ccggacaagt atggtcaatg
     9901 aaactcaaag ttcgtgcagt tcatggccaa cttaatgatg gcggctttga tagccagcgt
     9961 tatgccattg cccagcatca gccgctgacc ggccgctttc tgcaggcaag tgtcattgaa
    10021 ccgaattgta gcctgcgtgc acagtatctg gcgtcattac aaacaacgct gcaaccctat
    10081 ccgtggaatg cggttattct tggtttaggt atgggggaac ggttatccgt tcccaaagaa
    10141 atcaaaaata tcatgcgcga tactggaacg gcgcatttaa tggcgatatc gggattgcat
    10201 atcgcttttg cggcgttgct ggctgccgga ctcattcgca gtggacaaat ttttctgcct
    10261 gggcgctgga tccactggca aatgccatta attggcggaa tctgctgtgc tgctttttat
    10321 gcctggctga ctgggatgca acctcctgca ttgcgtaccg tggtggcgct tgccatgtgg
    10381 ggaatgctta agttaagtgg gcgacagtgg agtggctggg atgtatggat atgttgtctg
    10441 gcggcaattt tgctgatgga tcctgttgcc attctttcgc aaagtttatg gctctctgcc
    10501 gctgcggtcg cggcgctgat tttttggtat cagtggtttc cctgtccgga gtggcaactg
    10561 ccgccagtat tgcgcgcggt tgttgccctc atccatctac aactgggaat cacgctcctg
    10621 ctaatgcctg tgcaaatcgt cgtatttcat ggcattagtc tgacctcgtt tattgcaaac
    10681 ctatttgcaa ttcccctggt gacatttatc acggttccgt tgatcctcgc cgcgatggtt
    10741 atgcatttaa gcgggccgtt aatcgtggag caaggagtat ggtttcttgc cgaccggtct
    10801 ttggctttgc ttttctgggg gttaaagagt ttgccagaag ggtggatcaa cattgctgaa
    10861 cgttggcaat ggctatcatt ttccccatgg ttcttactgg tggtatggcg attaaacgcc
    10921 tggcgaacgt tgccagcaat gtgtgtggct ggaggcttgc tgatgtgctg gccgctgtgg
    10981 caaaaacctc gacctgacga gtggcaagtg tacatgcttg atgtcgggca agggctggca
    11041 atggtgatag ccagaaacgg caaagcgatt ctctatgaca cgggactggc ctggcctgaa
    11101 ggggatagtg ggcaacaact gattatcccc tggctccact ggcataatct tgaaccggaa
    11161 ggcgttattc tgagtcatga acatctggat caccggggag ggctggactc aatattgcat
    11221 acatggccga tgttatggat cagaagtccg ttaaactggg aacaccatca gccctgtgtg
    11281 cgtggcgaag cgtggcaatg gcaaggattg cgtttcagcg cgcactggcc tttacaaggt
    11341 agcaacgata aaggaaataa ccattcctgt gtggttaagg ttgatgacgg gacgaatagc
    11401 attcttctaa ccggtgatat tgaagcccct gctgaacaaa agatgctaag ccgttactgg
    11461 cagcaaatgc aggcaacatt acttcaggta cctcaccatg gcagtaatac ctcatcatcg
    11521 ttgccattaa ttcagcgagt gaatggaaaa gtggcactcg catcggcatc gcgctataac
    11581 gcatggcgac tgccctcaag caaagttaaa catcgctatc aacaacaggg ttataagtgg
    11641 cttgatactc cacatcaggg tcaaataacg gtcaattttt cagcgcaagg ctggcggatt
    11701 agcagcctca gagagcaaat tttacctcgt tggtatcatc agtggtttgg cgtgccagtg
    11761 gataacgggt agaatatgcg gctatttcaa caaatgctgg ttttttgaat gcataacgac
    11821 aaagatctct ctacgtggca gacattccgc cgactgtggc caaccattgc gccttttaaa
    11881 gcgggtctga tcgtggcggg cgtagcgtta atcctcaacg cagccagcga taccttcatg
    11941 ttatcgctcc ttaagccact tcttgatgat ggctttggta aaacagatcg ctccgtgctg
    12001 gtgtggatgc cgctggtggt gatcgggctg atgattttgc gtggtatcac cagctatgtc
    12061 tccagctact gtatctcctg ggtatcagga aaggtggtaa tgaccatgcg tcgccgcctg
    12121 tttggtcaca tgatgggaat gccggtttca ttctttgaca aacagtcaac gggtacgctg
    12181 ttgtcacgta tcacctacga ttccgaacag gttgcttctt cctcttccgg cgcactgatt
    12241 actgttgtgc gtgaaggtgc gtcgatcatc ggcctgttca tcatgatgtt ctattacagt
    12301 tggcaactgt cgatcatttt gattgtgctg gcaccgattg tttcgattgc gattcgcgtt
    12361 gtatcgaagc gttttcgcaa tatcagtaaa aacatgcaga acaccatggg gcaggtgacc
    12421 accagcgccg aacaaatgct gaaaggccat aaagaagtat tgattttcgg tggtcaggaa
    12481 gtggaaacga aacgcttcga taaagtcagc aaccgaatgc gtcttcaggg gatgaaaatg
    12541 gtttcagcct cttctatctc tgatccgatc attcagctga tcgcctcttt ggcgctggcg
    12601 tttgttctgt atgcggcaag cttcccaagt gtcatggata gcctgactgc cggtacgatt
    12661 accgttgttt tctcttcaat gattgcactt atgcgtccgc tgaaatcgct gaccaacgtt
    12721 aacgcccagt tccagcgcgg tatggcggct tgtcagacgc tgtttaccat tctggacagt
    12781 gagcaggaga aagacgaagg taagcgcgtg atcgagcgtg cgactggcga cgtggaattc
    12841 cgcaatgtca cctttactta tccgggacgt gacgtacccg cattgcgtaa catcaacctg
    12901 aaaattccgg cagggaagac ggttgctctg gttggacgct ctggttcagg taaatcaacc
    12961 atcgccagcc tgatcacgcg tttttacgat attgatgaag gcgaaatcct gatggatggt
    13021 cacgatctgc gcgagtatac cctggcgtcg ttacgtaacc aggttgctct ggtgtcgcag
    13081 aatgtccatc tgtttaacga tacggttgcc aacaacattg cttacgcaag gactgaacag
    13141 tacagccgtg agcaaattga agaagcggcg cgtatggcct acgctatgga cttcatcaat
    13201 aagatggata acggtctcga tacagtgatt ggtgaaaacg gcgtgctgct ctctggcggt
    13261 cagcgtcagc gtattgctat cgctcgagcc ttgttgcgtg atagcccgat tctgattctg
    13321 gacgaagcta cctcggctct ggataccgaa tccgaacgtg cgattcaggc ggcactggat
    13381 gagttgcaga aaaaccgtac ctctctggtg attgcccacc gcttgtctac cattgaaaag
    13441 gcagacgaaa tcgtggtcgt cgaggatggt gtcattgtgg aacgcggtac gcataacgat
    13501 ttgcttgagc accgtggcgt ttacgcgcaa cttcacaaaa tgcagtttgg ccaatgatcg
    13561 aaaaaatctg gtctggtgaa tcccctttgt ggcggctatt gctgccactc tcctggttgt
    13621 atggcctggt gagtggcgcg atccgtcttt gctataaact aaaactgaag cgcgcctggc
    13681 gtgcccccgt accggttgtc gtggttggta atctcaccgc aggcggcaac ggaaaaaccc
    13741 cggtcgttgt ctggctggtg gaacagttgc aacagcgcgg tattcgcgtg ggggtcgtat
    13801 cgcggggata tggtggtaag gctgaatctt atccgctgtt attgtcggca gataccacca
    13861 cagcacaggc gggtgatgaa cctgtgttga tttatcaacg cactgatgcg cctgttgcgg
    13921 tttctcccgt gcgttctgat gcgataaaag ccattctggc gcaacaccct gatgtgcaga
    13981 tcatcgtaac cgacgacggt ttacagcatt accgtctggc gcgtgatgtg gaaattgtcg
    14041 ttattgatgg tgtgcgtcgc tttggcaatg gctggtggtt gccggcgggg ccaatgcgtg
    14101 agcgagcggg gcgcttaaag tcggttgatg cggtaatcgt caacggtggt gtcccccgca
    14161 gcggtgaaat ccccatgcat ctgctgccgg gtcaggcggt gaatttacgt accggtacgc
    14221 gttgtgacgt tactcagctt gaacatgtag tggcgatggc ggggattgga catccgccgc
    14281 gcttttttgc cacgctgaag atgtgcggcg tacaaccgga aaaatgtgta ccgctggccg
    14341 atcatcagtc tttgaaccat gcggatgtca gcgcgttggt aaacgccggg caaacgctgg
    14401 taatgactga aaaggatgcg gttaaatgcc gggcctttgc agaagaaaat tggtggtatt
    14461 tgcctgtaga cgcacagctt tcaggtgatg aaccagcgaa actgcttgcg caactaacct
    14521 cgctggcttc tggcaactag ttacgccgcg gcagcgttcg attgatggag tcatgaatgt
    14581 cgctgccgca cctctctctt gctgatgcgc gtaatcttca cctcgccgcg caaggcctgt
    14641 taaacaaacc ccgccgtcga gcgtcgttgg aggatattcc ggcaacgatc tcccgcatgt
    14701 ccttgctgca aatcgatacc atcaatattg ttgcccgtag cccatatctg gtgcttttca
    14761 gtcgtctggg aaattatcct gcccagtggc tggatgagtc tctggcgcgt ggcgaattaa
    14821 tggaatactg ggcgcatgaa gcctgcttta tgccgcgtag cgattttcgt cttattcgcc
    14881 accgcatgct ggcacctgaa aaaatgggct ggaaatacaa agacgcctgg atgcaggaac
    14941 atgcggcgga aattgcactg ttaattcagc atattcatga taaggggcca gtacgttcag
    15001 ccgattttga gcatcctcgt aaaggggcga gcggctggtg ggagtggaag ccgcataaac
    15061 gacatctgga aggtttattt actgccggaa aggtgatggt gattgaacgg cgcaacttcc
    15121 agcgcgttta tgatttaact caccgtgtca tgcctgactg ggatgatgag cgcgatctcg
    15181 tttcgcaagc agaagcagaa atcatcatgc tggataacag tgcgcgtagc ctgggaatat
    15241 ttcgcgaaca gtggctggca gattactacc ggctaaaacg tccggcactg gcggcgtggc
    15301 gtgaagcgag ggctgaacag cagcaaatca ttgctgtgca tgttgaaaaa ttgggcaatc
    15361 tttggctgca tgctgatttg ctgccgctac tcgagcgtgc gctggccgga aagctcactg
    15421 caacgcacag cgcggtactt tcgccttttg atcctgttgt ctgggatcgc aaacgcgcag
    15481 agcagctttt tgattttagc taccggctgg agtgctatac cccagcgccg aaacgccagt
    15541 atggctattt tgttctgccg ttattacatc gtgggcaatt agttgggcga atggatgcca
    15601 aaatgcatcg ccagacaggc atccttgaag ttatctctct gtggttacag gaaggcatta
    15661 aaccaacgac aacgctgcaa aaagggttac gtcaggcgat tactgatttc gctaactggc
    15721 agcaggcaac gcgggtgaca ttaggacgct gcccgcaagg cctctttact gattgccgca
    15781 ccggctggga aatagacccc gtcgcataaa tgattatgat aagatttatg cattcataac
    15841 ccgatccatc tggaggaact atggatcatc gtctgcttga aatcattgcc tgcccggttt
    15901 gcaacggaaa actttggtat aaccaggaaa aacaagaact tatttgcaaa ctggacaacc
    15961 tggctttccc gctgcgcgat ggcattccag tgttgctgga aacggaagcc cgcgtgctga
    16021 ctgctgatga gagtaaatca tgagttttgt ggtcattatt cccgcgcgct acgcgtccac
    16081 gcgtctgccc ggtaaaccat tggttgatat taacggcaaa cccatgattg ttcatgttct
    16141 tgaacgcgcg cgcgaatcag gtgccgagcg catcatcgtg gcaaccgatc atgaggatgt
    16201 tgcccgcgct gttgaagccg ctggcggtga agtatgtatg acgcgcgccg atcatcagtc
    16261 aggaacagaa cgtctggcgg aagttgtcga aaaatgcgca ttcagcgacg acacggtgat
    16321 cgttaatgtg cagggggatg aaccgatgat ccctgcgaca atcattcgtc aggttgctga
    16381 taacctcgct cagcgtcagg tgggtatggc gactctggcg gtgccaatcc acaatgcgga
    16441 agaagcgttt aacccgaatg cggtgaaagt ggttctcgac gccgaagggt acgcactgta
    16501 cttctctcgc gccaccattc cgtgggatcg tgatcgtttt gcaaaagacc ttgaaaccgt
    16561 aggcgataac ttcctgcgtc atcttggtat ttatggctac cgagcaggct ttatccgtcg
    16621 ttatgttacc tggcagccaa gtccgttaga acatatcgaa atgttagagc agcttcgtgt
    16681 tctgtggtac ggcgaaaaaa tccacgttgc tgtcgcccgg gaagttcctg gcacaggtgt
    16741 ggatacccct gaagatctcg agcgcgttcg cgctgaaatg cgctaatttc acttcgcgac
    16801 actccagcca attttgggag gagtgtcgta ccgttacgat tttcctcaat ttttcttttc
    16861 aacaattgat ctcattcagg tgacatcttt tatattggcg ctcattatga aagcagtagc
    16921 ttttatgagg gtaatctgaa tggaacagct gcgtgccgaa ttaagccatt tactgggcga
    16981 aaaactcagt cgtattgagt gcgtcaatga aaaagcggat acggcgttgt gggctttgta
    17041 tgacagccag ggaaacccaa tgccgttaat ggcaagaagc tttagtacgc ccggaaaagc
    17101 ccgacaactg gcatggaaaa ccaccatgct ggcaagaagt gggactgtcc gtatgccgac
    17161 tatttatggt gtgatgacgc atgaagaaca ccccggcccc gatgtcctgc tactggagcg
    17221 gatgcgtggt gtttcggtgg aggcaccagc ccgaacacca gaacgctggg aacagctcaa
    17281 agaccaaatc gttgaagcct tactggcctg gcaccgtcag gacagtcgcg gttgcgtcgg
    17341 cgcggtcgac aatactcagg aaaatttctg gccctcatgg taccggcaac atgttgaagt
    17401 gctatggacc acgctcaatc agttcaataa caccggtctg acgatgcagg ataagcggat
    17461 cctgtttcgc actcgcgaat gtctcccggc attatttgaa ggttttaacg acaattgtgt
    17521 gctgattcac ggtaacttct gtttacgcag catgctgaaa gattcgcgca gcgatcagtt
    17581 actggcgatg gtcgggccgg gactaatgct ttgggcaccg cgagaatacg aactgttccg
    17641 actaatggat aattctctgg cagaagattt gctctggagt tacctgcaac gcgcgccagt
    17701 ggcggagtcg ttcatctggc ggcgttggtt gtatgtgtta tgggatgaag ttgcgcaact
    17761 ggttaatacc ggacgattta gtcggcgcaa cttcgatctg gcatcaaaat cactcttgcc
    17821 gtggctcgcc tgacgaacct tttagccact gccagatgcg gccaagcgtt tcatagccaa
    17881 cacgatcgct atgcatcaac cagaccggag aagggattgc ccgttcccac gggttaagcg
    17941 gcgagtcgat ggccaactga ttcgccgggg ctggtagcgg atttaaccct tcctgctgaa
    18001 aaaagatcat cgcccgcggc agatgtgatg cggaggtcac cagcaggaaa ggtgcgtcac
    18061 caatcgcctg tttcactgct gcagcttctt cttcggtatc ttttggcaaa tccagggtga
    18121 taatttgctc gcgcggcacg cccagcgatt gcgcaactct ggcaccaact tcggctgtgc
    18181 tcaccgtatt ggttttagct acgcctcccg tgaagatcag ttttgatccc ggattttcgc
    18241 gccataagcg aataccttca ttcaggcgtg gcagactgtt attgattaaa ttcgagcttg
    18301 gtgcccactg cgggttccag gtataaccac ctccgagcac cacgatatag tccacttttt
    18361 gcgaattatt ccatgtcgga taggtgcttt cgatgggacg cagcaggcgg tcggctaccg
    18421 gttgcaaact caataacaag agtgccagcc acccaatgct aataaaaatc ttcccggttt
    18481 tttgaaaacg gctaaaccac agcagcgcca ggccagcgcc aataattaac aacatcagcg
    18541 gaagtggcag cagcataccg ccgatcactt ttttcagtgt aaaaagcatc ctttctggtt
    18601 ccttttttga ccatatagca agggatcgcc agcgatatta caccagacgg gttcattctc
    18661 gccgtggctg tgacaaaata gcgtctttat cagaaaacgt cttagccaac cggtggagaa
    18721 agcaatgcag gatcgcaatt ttgatgatat tgcggaaaag ttttcccgta acatttacgg
    18781 caccaccaaa gggcagcttc gacaggctat tctgtggcag gatctcgatc gcgtgctggc
    18841 ggaaatgggc ccgcaaaaac tgcgtgtgct ggatgctggc ggtggagaag ggcagaccgc
    18901 aatcaaaatg gctgagcacg ggcatcaggt cattttatgc gatctttctg cgcagatgat
    18961 cgaccgcgca aaacaggcgg cagaagcaaa aggtgtgagc gacaacatgc aatttataca
    19021 ttgcgccgct caggatgttg cttcgcattt ggaaacgccc gttgatctga tattgttcca
    19081 tgcggtgctc gagtgggtgg ccgatccccg cagcgtatta cagaccctgt ggtcagtgtt
    19141 gcgtccaggc ggtgtgttgt cgttaatgtt ctacaatgcg cacggcttgc tgatgcataa
    19201 catggtcgcc gggaattttg attacgtgca ggcgggaatg ccgaaaaaga aaaaacggac
    19261 gctttcgcca gattatccac gcgacccggc gcaggtttat ctgtggctgg aagaagctgg
    19321 ttggcaaatt atgggtaaga caggcgttcg cgtgtttcat gattatctgc gcgagaagca
    19381 ccagcagcgc gactgctatg aagcattact tgaattagaa acgcgttatt gccgtcagga
    19441 accgtatatt accctggggc gttatattca tgtcaccgcg cgcaaaccgc agagcaagga
    19501 taaagtatga gtgaattttc ccagacagtc cccgaactgg ttgcctgggc cagaaaaaat
    19561 gacttctcca tctcgctgcc ggtagaccga ctctcttttc tgctggcggt tgccacgctg
    19621 aacggcgagc gtctggatgg tgagatgagt gaaggcgagc tggtggatgc attccgccat
    19681 gtgagtgatg cgtttgagca aaccagcgaa accatcggcg tgcgcgccaa caacgcgatc
    19741 aacgacatgg tgcgtcaacg tctgctgaac cgctttacca gcgagcaggc ggaagggaac
    19801 gcaatttacc gtctgacgcc gctcggcatc ggcattactg actactacat ccgtcagcgc
    19861 gagttttcta cgctgcgcct ttctatgcag ttgtcgattg tggcgggtga gctcaaacgc
    19921 gcggcagatg ccgccgaaga gggcggtgat gaatttcact ggcaccgtaa tgtttatgcg
    19981 ccactgaaat attcggtagc agaaattttc gacagtatcg acctgacgca acgtctgatg
    20041 gacgaacagc agcagcaggt gaaggacgat atcgcccagt tgctgaacaa agactggcgg
    20101 gcggcgatct ccagctgtga attgttgctt tcggaaactt ccggaacgct gcgtgaattg
    20161 caggatacgc tggaagcggc aggcgacaaa ttgcaggcta atctgttgcg cattcaggat
    20221 gcgacgatga cccatgacga tctgcatttt gtcgatcgtc tggtgttcga tctgcagagc
    20281 aaacttgacc gtattatcag ttggggccag caatccatag acttgtggat tggctacgac
    20341 cgccacgtac acaaatttat ccgtaccgca atcgatatgg ataaaaaccg cgtctttgct
    20401 cagcggttac gtcagtcggt acaaacctat tttgatgagc cgtgggcgct aacttatgcc
    20461 aatgccgatc gtctgctgga tatgcgtgac gaagagatgg cactgcgcga tgaagaagtg
    20521 actggggaac ttcctgagga tctggagtac gaagagttta acgagatccg cgaacagctg
    20581 gcggcgatca tcgaagaaca acttgccgtg tacaaaacca gacaagtgcc gctggatctt
    20641 ggtctggtgg tacgcgaata tctgtcacag tatccgcgtg cacgtcactt tgacgttgcg
    20701 cgcattgtta ttgatcaggc ggtacgtctt ggcgtagcgc aagcagattt caccggactg
    20761 ccagcgaaat ggcagccgat taatgattac ggagccaagg tacaggcgca tgtcatcgac
    20821 aaatattgaa caagtgatgc cggttaagct ggcgcaggcg ctggcgaatc cgttatttcc
    20881 ggcgctggac agcgccttac gttcaggccg ccatattggc ctcgacgaac tggataatca
    20941 tgcattcctg atggattttc aggaatatct ggaagagttt tacgcgcgtt ataacgttga
    21001 gcttattcgc gcaccggaag ggttcttcta tttacgccca cgttccacca ctcttatccc
    21061 gcgttccgtc ttgtcggaac tggatatgat ggtcgggaaa atcctctgtt atctctatct
    21121 cagcccggaa cggctggcga acgaggggat tttcacccag caggaactgt acgacgaact
    21181 gctcaccctg gccgatgaag cgaaactgct gaaactggtg aacaaccgtt caaccggttc
    21241 agacgttgac cgccagaagt tgcaggaaaa agtacgttct tcgctcaacc gtctgcgtcg
    21301 tttgggtatg gtgtggttta tgggccacga cagcagcaag ttccgcatta ccgaatcggt
    21361 gttccgcttc ggagccgatg tgcgtgctgg cgacgatccc cgtgaagcac agcgtcgcct
    21421 gattcgtgat ggcgaagcaa tgccgattga aaatcatctg caactcaacg atgaaaccga
    21481 agagaatcag ccagatagcg gagaggaaga ataatgattg aacgcggtaa atttcgctca
    21541 ctgacgctga ttaactggaa cggttttttt gcccgaactt ttgacctcga tgaactggtt
    21601 acgacgctct ccggcggtaa cggggcgggt aaatccacca ccatggcggc gttcgttacg
    21661 gcgctgatcc ccgacctgac cctgctgcat ttccgtaaca ccacggaagc cggggccacc
    21721 agcggttcgc gcgataaagg tctgcacggt aagctgaaag cgggtgtctg ttattcgatg
    21781 ctcgacacca ttaactcgcg ccaccagcgc gtggtggtcg gtgtgcgtct gcaacaggtt
    21841 gccggacgcg atcgtaaagt ggatatcaaa ccgtttgcca ttcagggttt accgatgtcg
    21901 gtgcagccga cacaactggt gaccgaaacc ctgagcgaac gtcaggcgcg cgtgctgccg
    21961 cttaacgagc tgaaagacaa gctcgaggcg atggaaggcg tgcagtttaa acagttcaac
    22021 tccattaccg attaccactc gctgatgttc gatctgggca tcatcgcgcg tcgtctgcgc
    22081 tcagcgtctg accgtagtaa attctatcgt ctgatcgaag cttcgctgta cggcgggatc
    22141 tccagcgcca ttacgcgctc tctgcgcgac tacctgttgc cggaaaacag cggcgtgcgg
    22201 aaagcgttcc aggacatgga agcggcgctg cgcgaaaacc gcatgacgct ggaagcgatt
    22261 cgtgtcaccc agtcggaccg cgacctgttt aagcatctga ttagcgaagc caccaactac
    22321 gtggcggcgg actacatgcg tcacgccaac gagcgccgtg tccatctcga caaagccctg
    22381 gagtttcgtc gcgagctaca cacttcgcgt cagcaactgg cggctgagca gtacaaacac
    22441 gtcgatatgg cgcgtgagct ggcagagcac aacggtgccg aaggcgatct ggaagcagat
    22501 tatcaggcgg ccagcgatca cctgaacctg gtgcaaaccg cactgcgtca gcaggagaag
    22561 atcgaacgtt acgaagcgga tctcgatgag ctgcagatcc gtctggaaga gcaaaacgaa
    22621 gtggtggcag aagccatcga acgccaggaa gagaatgagg ctcgtgcgga agctgccgaa
    22681 ctggaagtgg acgagctgaa aagccagctt gctgactacc agcaggcgct ggacgtccag
    22741 caaacgcgcg cgatccagta taaccaggcg attgctgcgc ttaatcgtgc caaagaactg
    22801 tgccatctgc cggacttaac cgccgacagc gccgccgaat ggctggaaac cttccaggcg
    22861 aaagagctgg aagcgactga aaaaatgctc tctcttgagc agaaaatgag catggcgcaa
    22921 accgcgcaca gccagtttga gcaggcttat cagctggtgg tggcaatcaa cggcccgctg
    22981 gcgcgtaacg aggcgtggga tgtcgctcgc gaactgctgc gcgaaggggt cgatcagcgt
    23041 cacctggcag agcaggttca gccgttgcgg atgcgcttaa gcgaactgga acagcgtctg
    23101 cgtgagcagc aagaagctga gcgtctgctg gcagatttct gcaaacgtca gggcaagaat
    23161 tttgatattg atgaactgga agctctgcat caggagctgg aagcacgcat tgcctctctt
    23221 tccgatagcg tctctaacgc ccgagaagag cggatggcac tgcgccagga gcaggaacag
    23281 ctgcagtctc gcattcagag tttgatgcag cgtgcgccgg tttggctggc tgcgcaaaac
    23341 agtctcaacc agttgagcga acagtgcggc gaagagttct cctccagcca ggatgtcacc
    23401 gaatatctgc aacagttgct ggagcgtgag cgcgaagcca ttgttgaacg cgatgaagta
    23461 ggcgcgcgca aaaacgccgt cgatgaagag atcgaacgtt taagccagcc aggtggttct
    23521 gaagaccagc gtttgaatgc gctggcggag cgttttggcg gcgtgctgct gtcagaaatt
    23581 tatgacgacg ttagcctgga agatgcgccg tacttctcag cgctgtatgg cccgtcacgc
    23641 cacgccatcg tggtgccaga tctgtcacag gtaaccgaac acctggaagg cttgaccgat
    23701 tgcccggaag atctctatct gatcgaaggg gatccgcagt cattcgatga cagcgtgttc
    23761 agcgttgatg agctggaaaa agcggtggtg gtgaaaatcg ccgatcgtca gtggcgttat
    23821 tcacgtttcc cggaagtgcc gctgtttggt cgtgctgcgc gtgaaagccg tattgaaagc
    23881 ctccatgccg agcgtgaagt gctttccgaa cgcttcgcca cgctctcctt tgatgtacag
    23941 aaaacccagc gtctgcatca ggcgttcagc cgctttatcg gcagccacct ggcggtggcg
    24001 tttgagtctg atccggaagc cgaaatccgt caactgaaca gccgtcgcgt cgaactggag
    24061 cgggcgttga gtaatcatga aaatgataac cagcagcagc gtattcagtt tgagcaggcg
    24121 aaagagggtg ttacggcgct gaaccgcatt ctgccgcgtc tcaacttgtt ggctgatgac
    24181 agcctggcgg atcgcgtcga tgaaatccgc gaacgtctgg atgaagccca ggaagccgcg
    24241 cgttttgttc agcagttcgg taatcaactg gcgaaactgg aaccgatcgt ttcggtattg
    24301 cagagtgacc cggaacagtt cgaacaatta aaagaagatt acgcgtactc tcagcagatg
    24361 cagcgcgatg cccgtcagca ggcgtttgcc ctgacggaag tggtgcagcg tcgtgcgcac
    24421 tttagctact ctgactcggc agaaatgctt agcggtaaca gcgatctcaa cgaaaaactg
    24481 cgtgaacgtc tggaacaggc ggaagcggag cgtacccgcg cgcgtgaagc gttgcgcgga
    24541 cacgcagcgc agttgagtca gtacaaccag gtgctggctt cgctgaaaag ttcttacgac
    24601 accaaaaaag agctactcaa cgatctgcaa cgtgaattgc aggatatcgg cgtgcgtgct
    24661 gatagcgggg cagaagagcg ggcgcgtatt cgccgtgacg agttgcacgc gcaactgagc
    24721 aataaccgtt cacgccgcaa tcaactggaa aaagcgctta ccttctgcga agcagagatg
    24781 gacaacctga cccgcaaact gcgcaagctg gagcgggatt actttgagat gcgcgagcag
    24841 gtagtgaccg cgaaagcggg ctggtgtgca gtcatgcgca tggtgaaaga taacggcgtt
    24901 gagcgccgct tacaccgtcg tgagctggct tatctctccg ctgatgattt gcgttccatg
    24961 tcggataagg cgttaggtgc gctgcgtctg gcggtggcgg ataacgaaca tctgcgcgac
    25021 gtgctgcgta tgtcggaaga tccaaaacgt ccggaacgta aaattcagtt cttcgtggcg
    25081 gtttatcagc atctgcgtga acgtattcgt caggatatta ttcgtaccga tgatccggtg
    25141 gaagctatcg aacagatgga gatcgaactt agccgtctga ccgaagagtt aacctcccgc
    25201 gaacagaaac tggcgatcag ttcccgcagc gtggcgaaca ttattcgcaa aaccattcag
    25261 cgcgagcaga accgtatccg tatgctcaac cagggcttgc agagcgtatc gtttggccag
    25321 gtgaacagcg tgcgtctcaa cgtgaacgtg cgtgaaacgc acgccatgct gctggatgtg
    25381 ctctctgaac agcatgagca acatcaggat ctgtttaaca gcaaccgtct gaccttctca
    25441 gaagcgctgg cgaaactgta tcagcgtctt aatccgcaga ttgatatggg gcaacgcacg
    25501 ccgcagacca ttggcgaaga actgctggat taccgcaact atctggaaat ggaagttgag
    25561 gttaaccgtg gttctgatgg ctggctgcgc gcagaatctg gcgctctgtc gaccggtgag
    25621 gcgattggta ccggtatgtc gattctggtg atggtggtac aaagctggga agatgaatct
    25681 cgccgcctgc gcggtaaaga tatctctcct tgccgcctgc tgttcctcga tgaagcagcg
    25741 cgactggatg ctcgttctat cgccacgctg tttgaattgt gtgaacgttt gcaaatgcag
    25801 ctcatcatcg cagcgccgga aaatatcagt ccggaaaaag gcaccaccta taaactggtg
    25861 cgtaaagtct tccagaatac cgaacacgtt cacgtcgtcg gcctgcgagg atttgcgccg
    25921 caactccctg aaacgcttcc aggaagtgac gaagcgcctt cccaggcgag ctaagattga
    25981 ggcggcagcg atgccgcctt tcctgtttct gaaaactccg tttctgcact aaaaaagtgc
    26041 cacattctgg cgcgcttttc tttaaacttc tttacattag gttatgtaaa aacgtatcgg
    26101 cgtttatata ctgaagataa gcctgatgag taacaggctt gctcgtcata ctttcgtgag
    26161 tattggcgtt gtacaggcaa gtcgtaaaat aacagcctgg ctattcagag tatgataaaa
    26221 acagggggca agggatgttg cttaatatga tgtgtggtcg tcggctgtcg gcaatcagtt
    26281 tgtgcctggc cgtaacattc gctccactgt tcaatgcgca ggccgatgag cctgaagtaa
    26341 tccctggcga cagcccggtg gctgtcagcg aacagggcga ggcactgccg caggcgcagg
    26401 ccacggcaat aatggcgggg atccagccat tgcctgaagg tgcggcagaa aaagcccgca
    26461 cgcaaatcga atctcaatta cctgcaggct ataagccggt ttatcttaac cagcttcaac
    26521 tgttgtatgc cgcacgcgat atgcaaccca tgtgggaaaa ccgtgatgct gttaaagcct
    26581 tccagcaaca gctggcagag gtggcgattg ccggtttcca gccgcagttt aataaatggg
    26641 tagagttact gaccgatcct ggtgttaacg ggatggcacg cgacgtggtg ctctctgatg
    26701 cgatgatggg ctatctccat ttcattgcaa atattccggt caaaggcact cgctggctat
    26761 atagcagtaa accttatgcg ctttcaacgc cgccgctttc ggtgattaac caatggcagc
    26821 tggcgctgga taaaggtcaa ttgccgacgt ttgttgcagg tctggcaccg cagcatccgc
    26881 aatatgcagc gatgcatgaa tcgttactgg ccttactcag tgacaccaaa ccgtggcccc
    26941 aactgaccgg caaagcaacg ttgcgcccag ggcagtggag taacgacgta ccggcgttgc
    27001 gcgaaatatt gcaacgcaca ggcatgttgg acggggggcc gaaaattact ctacctggcg
    27061 atgacacgcc aactgacacg gtagtcagcc catccgctgt tactgttgaa acagcagaaa
    27121 ctaagccgat ggacaagcaa acgacgtctc gtagtaaacc tgcgcctgcc gttcgtgccg
    27181 cctacgataa tgaactggtg gaagccgtta aacgttttca ggcatggcaa ggattgggag
    27241 cagatggcgc tattggcccg gcaacgcgtg actggttaaa cgtaacgccc gcccagcgtg
    27301 ctggcgtgtt ggcactcaac atccagcgat tgcgcttgct gccaacagag ctttctaccg
    27361 ggatcatggt taacattccg gcctattcgc tggtctacta tcagaacggc aatcaggtgc
    27421 tggattcgcg agtcattgtc ggtcgccccg atcgcaaaac gccgatgatg agcagtgcac
    27481 ttaacaacgt agtggtaaac ccgccgtgga acgtaccacc aactctggca cgcaaagata
    27541 ttctgccgaa agtgcgcaac gatccgggat atctcgaaag ccatggctat acggtgatgc
    27601 gcggctggaa cagcagagaa gcgattgacc catggcaggt tgactggtct acaatcacgg
    27661 cctcgaattt accgttccgc ttccagcagg ctccaggccc acggaactcg ctggggcgct
    27721 ataaattcaa tatgccgagt tcagaggcca tttatttgca tgacacgccg aaccacaatc
    27781 tgttcaaacg tgatacacgc gcattgagct caggctgtgt acgagtgaat aaagcttccg
    27841 atctggcgaa tatgctgttg caggatgcag gatggaatga caaacgtatt tctgatgcgc
    27901 tgaagcaggg cgatacgcgt tacgtcaata ttcggcagtc gattccggtg aatctctact
    27961 atctgacggc ctttgttggt gcagatggtc gtacccagta tcgtacagat atttacaatt
    28021 atgatctgcc tgcgcgatcc agctcgcaaa tcgtatcgaa agcggaacaa ttaatcaggt
    28081 aaatgaagca gttcggggaa atcagttgtc gtaataatta gcatgatcgg gggcgattct
    28141 ctgcagcccc cgtcactgct ggggttgagt catcttgacg tcagctttac tgacggttaa
    28201 ggtgcctctt gtgcgccaga agtgcatata aacgataaca ttgacctgta gacttgatta
    28261 tcatggacaa attcgacgct aatcgccgca aactgctggc gcttggtggc gttgcactcg
    28321 gtgccgccat cctgccgacc ccggcgtttg caacactctc taccccacgc ccgcgcattt
    28381 tgacactcaa taatcttcat accggagagt caatcaaagc ggagtttttc gatggcagag
    28441 gctatattca ggaagaattg gcaaaactta accatttttt ccgcgattac cgcgcgaaca
    28501 aaataaagtc catcgaccca ggattgttcg atcagttgta tcgcctgcaa gggttattag
    28561 gcacccgcaa accggtgcaa ctcatttccg gttatcgttc cattgatacc aacaatgaac
    28621 tacgcgcccg cagccgtgga gtagcgaaga aaagctatca cacgaaaggg caggcgatgg
    28681 atttccatat tgaaggtatc gcgttaagca atattcgcaa agccgcgtta tctatgcgcg
    28741 caggtggtgt aggatattac ccacgtagta actttgtgca tattgatacc gggccagcac
    28801 ggcactggta gtaatcgctt aacgaaacag gggcagtatg aactatcgta ttattccggt
    28861 caccgcattc tcccagaact gttcattgat ctggtgtgaa caaacccgac tggccgcact
    28921 ggtcgatcct ggcggcgatg cggaaaaaat caaacaggaa gttgatgcca gcggcctgac
    28981 actgatgcag atcctgctga ctcatggtca tctggaccac gttggcgcag cggcggaact
    29041 ggcgcaacat tacggcgtgc cggtttttgg cccggaaaaa gaagatgagt tctggctgca
    29101 aggcttgcct gcgcaaagtc gtatgtttgg tctggaagag tgccagccgc tgacgccaga
    29161 tcgttggctg aacgaaggcg ataccatcag catagggaat gtgactttac aggtgttaca
    29221 ttgccctggg catacgccgg gtcatgtcgt gttttttgat gagcgggcaa ggctgctgat
    29281 ttctggcgac gttattttca aaggcggagt agggcgcagt gactttccgc gtggcgatca
    29341 taatcaactg atttcttcaa tcaaagataa attgctgccc ctgggggatg acgtgacatt
    29401 tattccgggt cacggaccat tatcaactct tggttacgaa cgcctgcata atcccttcct
    29461 gcaagacgaa atgcccgtct ggtaaagacg tataaaaaag cccgctttca cagcgggctt
    29521 cgtttaacta gcctttacag cacggccaca atcgcttcgc acagcggagc catgttatct
    29581 ggcgtcatcc cggccacgtt cacacgacca gaagccactg catacacgcc aaactcttca
    29641 cgcagacgca gtacctgttc tttcgtcagg ccactgaagg agaacatacc gttctgtttg
    29701 atgataaagc tgaagtcgcg gtttgcccct ttttcctgca gcgtattgac gaacaactga
    29761 cgcatacgct gaatacgctg gcgcatatca gtcagctctt gttcccaaat cgcacgtaac
    29821 gcatcgttgc tcaggatggt ggcaacaaca gaagcgccgt gtgctggtgg gttagagtag
    29881 ttagcgcgaa tcgccgcttt catttggctg aatgcgcgat caacggtctc actgtcagca
    29941 gcaaccagag tacaagcgcc aacacgctcg ttgtacaggc caaagttttt agagtaggaa
    30001 ctggcaacaa tcagctcttt atgcatagcc gcgaaagcgc gcagtccttc agcatcttct
    30061 tccagaccac gggcaaaacc ctggtaagcg aagtcaaaca gcggtaacca gcctttctca
    30121 acggaaagtt gtgccagtgt ctgccattgt tccagcgtag ggtcgatacc ggttgggtta
    30181 tggcagcagc catggaacag cactacgtcg ccagcctgag cttcgttcag gctgttaatc
    30241 agtgcatcga agtcaagggt gtgattttcc gcatcataat aagcgtattc acgaacttcc
    30301 agacctgcag agttaaagac gcttttatgg ttcggccagc ttgggttgct cacccacaca
    30361 cgcttaacgc tggtattttt tgccaggaaa tcggcagcca cgcgtagtgc gccagtgcca
    30421 cccggagtct gtgccgtgcg agcacgtttg tcattgatca gggcgctacc tttaccaaac
    30481 agcagttcct gagtgcagcg accaaattca gggatgccgt caatgccgag gtaatttttg
    30541 gtggtttcat tttcgagcag atactgttca gcctttttca cactggtcag taccggggtt
    30601 ttgcccgtct catctttata gacaccaatc ccgaggttaa ttttgccggg acgttcatcg
    30661 gcacgaaaca gatcggccag gcccagaatc gggtcggcag gagcggcggt aatgttctca
    30721 aacatgacga ggttccatta tggttacaga agggaagtcc gctatcaggg taacgggaga
    30781 tttacaaaat tccaactatt actgatgaaa acgcaggctg tttttgcaag acgtgagatt
    30841 gctctgaaag gcataaaaaa aacaggacca acgtcctgtt ttttcggcat ttaacaaaga
    30901 ggtgtgctat tagaactggt aaacgatacc cacagcaacg gtgtcgtctg aacctacgcc
    30961 cagtttgttg tcagaatcga tctggttgat gatgtagtca acataggtgg acatgttttt
    31021 gttgaagtag taggttgcgc ccacttcaaa gtagttcacc agatcaacat caccgatacc
    31081 ttctacgtct ttcgctttag atttggtgta agcgatggac ggacgcagac cgaaatcgaa
    31141 ctggtattgc gcaactaaca gaacgtcttg cgttttgttg gcgaagccgc cttcaattgg
    31201 cgtagcgtta cgggtttcac cgtagttcgc tgccaggtag atgttgttcg cgtcatactt
    31261 cagaccagtt gcccactgtt cagctttttt accctgaccg cggaattcgg cttcctgggc
    31321 gtcggtacgg tctgctgcac cgtaagcacc tacgatacca aagccttcga attcgtagct
    31381 gatagagcca ccgacgccgt cgccgttgga acgctcagga ataccagcac gttcgttttt
    31441 gcccaggtac tgaacggcaa agttcaggcc gtcaaccaga ccgaagaagt tggagttacg
    31501 ataggtagca acgccgccta cacgaccaac gaagaagtca tcgctgtatg ccgtgtcacc
    31561 gccgaactca ggcagcatat cggtgtaacc cagtgcgtcg taaaccacac cgtagttacg
    31621 accgtagtcg atagaacccg catcagcgaa tttcagacct gcgaatgcca gacgagtttt
    31681 gttacctttc tgggcatcag cgccttcaga gttgttaccc tggaagttat attcccactg
    31741 accgtagccg gtcagatcgg aattgatttg tgtttcccct ttaaaaccaa gacgggcata
    31801 agttttgtcg ccgtttccgc cgtaactgtt tacaccattg tctttagaaa aataatgcag
    31861 accgacagct ttaccgtaca gatctacttt gttgccatct ttgttataga tttctgcagc
    31921 gtttgcagta cctgctacta acagagcagg gacgatcact gccagaatat tgcgcttcat
    31981 cattatttat taccctcatg gtttttttat gacacctgcc actgccgtca ataagttctg
    32041 tcaataaaaa tttacggaac tattgatgag agtttggtgt ctttatgtgt ctgcaggcat
    32101 ctttccattc aaactaacgt ttcgctaccg tgaaagtgct acaaaga
//
LOCUS       DADXDL010000057        31798 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.057, whole genome shotgun sequence.
ACCESSION   DADXDL010000057 DADXDL010000000
VERSION     DADXDL010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31798)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31798)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31798
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.057"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..688
                     /locus_tag="IRB70_002926"
     CDS             <1..688
                     /locus_tag="IRB70_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBC0632814.1"
                     /translation="ELAELAAVIDRLYEFHQLTEQRPTNKPKNCQHAVQVADASIRTP
                     DNKIILENLNFHVLPGKWLLLKGYSGAGKTTLLKTLSHCWPWFKGDISSPADSWYVSQ
                     TPLIKTGLLKEIICKALPLSVDDKSLSEVLHQVGLGKLATRIHDHDRWGDILSSGEKQ
                     RIALARLILRRPKWIFLDETTSHLEEQEAIRLLRLVREKLPTSGVIMVTHQPGVWNLA
                     DDICDISAVL"
     gene            726..3098
                     /locus_tag="IRB70_002927"
     CDS             726..3098
                     /locus_tag="IRB70_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor plug domain-containing
                     protein"
                     /protein_id="HBC0632815.1"
                     /translation="MKRVLIPGVILCGADVAQAVDDKNMYMHVFEEMTVYAPVPVPVN
                     GNTHYTSESIERLPTGNGNISDLLRTNPAVRMDSTQSTSLNQGDIRPEKISIHGASPY
                     QNAYLIDGISATNNLNPANESDASSATNISGMSQGYYLDVSLLDNVTLYDSFVPVEFG
                     RFNGGVIDAKIKRFNADDSSVKLGYRTTRSDWLTSHIDENNKSAFNQGSSGSTYYSPD
                     FKKNFYTLSFNQELADNFGVTAGLSRRQSDITRADYVSNDGIVAGRAQYKNVIDTALS
                     KFTWFASDRFTHDLTLKYTGSSRDYNTSTFPQSDREMGNKSYGLAWDMDTQLAWAKLR
                     TTVGWDHISDYTRHDHDIWYTELSCTYGDITGRCTRGGLGHISQAVDNYTFKTRLDWQ
                     KFTVGNVSHQPYFGAEYIYSDAWTERHNQSESYVINAAGKKTNHTIYHKGKGSLGIDN
                     YTLYMADRISWRNVSLMPGVRYDYDNYLSNHNISPRFMTEWDIFADQTSMITAGYNRY
                     YGGNILDMGLRDIRNSWTESVSGNKTLTRYQDLKTPYNDELAMGLQQKISKNVIARAN
                     YVYREAHDQISKSSRTDSATKTTITEYNNDGKTKTHSFNLSFELAEPLHISQVDINPQ
                     IVFSYIKSKGNLSLNNGYEESNTGDNQVVYNGNLVSYDSVPVADFNNPLKISLNMDFT
                     HQPSGLVWANTLTWQEARKARIILGKTNAQYISEYSDYKQYVDEKLDSSLTWDTRLSW
                     TPQFLKQQNLTFSADILNVLDSKTAVDTTNTGVATYASGRTFWLDVSMKF"
     gene            3155..5938
                     /locus_tag="IRB70_002928"
     CDS             3155..5938
                     /locus_tag="IRB70_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310126.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBC0632816.1"
                     /translation="MRNLCFLLTLVATLLLPGRLIAAALPQDEKLITGQLDNGLRYMI
                     YPHAQPKDQVNLWLQIHTGSLQEEDNERGVAHFVEHMMFNGTKTWPGNKVIETFESMG
                     LRFGRDVNAYTSYDETVYQVSLPTTQKQNLQQVMAIFSEWSNAATFEKLEVDAERGVI
                     TEEWRAHQDAKWRTSQARRPFLLANTRNLDREPIGLMDTVATVTPAQLRQFYQRWYQP
                     NNMTFIVVGDIDSKEALALIKDNLSKLPANKAAENRVWPTKAENHLRFNIINDKENRV
                     NGIALYYRLPMVQVSDEQSFIEQAEWSMLVQLFNQRLQERIQSGELKTISGGTARSVK
                     IAPDYQSLFFRVNAQDDNMQDAANALMAELATIDQHGFSAEELDDVKSTRLTWLKNAV
                     DQQAERDLRMLTSRLASSSLNNTPFLSPEETYQLSKRLWQQITVQSLAEKWQQLRKNQ
                     DAFWEQMVNNEVAAKKALSPAAILALEKEYANKKLAAYIFPGRNLSLTVDADPQAEIS
                     SKETLAENLTSLTLSNGAKVILAKSAGEEQKLQITAVSNKGDLSFPAQQKSLIALANK
                     AVSGSGVGELSSSSLKRWSAENSVTMSSKVSGMNTLLSVSARTNNPEPGFQLINQRIT
                     HSTINDNIWASLQNAQIQALKTLDQRPAEKFAQQMYETRYADDRTKLLQENQIAQFTA
                     ADALAADRQLFSSPADITFVIVGNVAEDKLVALITRYLGSIKHSDSSLAAGKPLTRAT
                     DNASVTVKEQNEPVAQVSQWKRYDSRTPVNLATRMALDAFNVALAKDLRVNIREQASG
                     AYSVSSRLSVDPQAKDISHLLAFTCQPERHDELLTLANEVMVKRLAKGISEQELNEYQ
                     QNVQRSLDIQQRSVQQLANTIVNSLIQYDDPAAWTEQEQLLKQMTVENVNTAVKQYLS
                     HPVNTYAGVLLPK"
     gene            6301..7701
                     /locus_tag="IRB70_002929"
     CDS             6301..7701
                     /locus_tag="IRB70_002929"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBC0632817.1"
                     /translation="MDKKQVTDLRSELLDSRFGAKSISTIAESKRFPLHEMRDDVAFQ
                     IINDELYLDGNARQNLATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVN
                     MVADLWHAPAPKNGQAVGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCG
                     PVQICWHKFARYWDVELREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYE
                     FPQPLHDALDKFQADTGIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHK
                     FGLAPLGCGWVIWRDEEALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRL
                     GREGYTKVQNASYQVAAYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTL
                     YDLSERLRLRGWQVPAFTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSD
                     HPKLQGIAQQNSFKHT"
     gene            7857..9392
                     /gene="gadC"
                     /locus_tag="IRB70_002930"
     CDS             7857..9392
                     /gene="gadC"
                     /locus_tag="IRB70_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance gamma-aminobutyrate antiporter
                     GadC"
                     /protein_id="HBC0632818.1"
                     /translation="MATSVQTGKAKQLTLLGFFAITASMVMAVYEYPTFATSGFSLVF
                     FLLLGGILWFIPVGLCAAEMATVDGWEEGGVFAWVSNTLGPRWGFAAISFGYLQIAIG
                     FIPMLYFVLGALSYILKWPALNEDPITKTIAALIILWALALTQFGGTKYTARIAKVGF
                     FAGILLPAFILIALAAIYLHSGAPVAIEMDAKTFFPDFSKVGTLVVFVAFILSYMGVE
                     ASATHVNEMSNPGRDYPLAMLLLMVAAICLSSVGGLSIAMVIPGNEINLSAGVMQTFT
                     VLMSHVAPEIEWTVRVISALLLLGVLAEIASWIVGPSRGMYVTAQKNLLPAAFAKMNK
                     NGVPVTLVISQLVITSIALIILTNTGGGNNMSFLIALALTVVIYLCAYFMLFIGYIVL
                     VLKHPDLKRTFNIPGGKGVKLVVAIVGLLTSIMAFIVSFLPPDNIQGDSTDMYVELLV
                     VSFLVVLALPFILYAVHDRKGKGNTGVTLEPINSQNAPKGHFFLHPRARSPHYIVMND
                     KKH"
     gene            9523..10842
                     /locus_tag="IRB70_002931"
     CDS             9523..10842
                     /locus_tag="IRB70_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 10 protein"
                     /protein_id="HBC0632819.1"
                     /translation="MDICSRNEKLAIRRPAILVALALLLCSCKSTPPESMVTPPAGSK
                     PPATTQQSSQPMRGIWLATVSRLDWPPLSSVNISNPTSRARVQQQAMIDKLDHLQRLG
                     INTVFFQVKPDGTALWPSKILPWSDLMTGKIGENPGYDPLQFMLDEAHKRGMKVHAWF
                     NPYRVSVNTKPGTIRELNSTLSQQPASVYVQHRDWIRTSGDRFVLDPGIPEVQDWITS
                     IVAEVVSRYPVDGVQFDDYFYTESPASRLNDNETYRKYGGAFASKADWRRNNTQQLIA
                     KVSHTIKSIKPEVEFGVSPAGVWRNRSHDPLGSDTRGAAAYDESYADTRRWVEQGLLD
                     YIAPQIYWPFSRSAARYDVLAKWWADVVKPTRTRLYIGIAFYKVGEPSKIEPDWMING
                     GVPELKKQLDLNDAVPEISGTILFREDYLNKPQTQQAVSYLQSRWGS"
     gene            11139..11180
                     /locus_tag="IRB70_002932"
     CDS             11139..11180
                     /locus_tag="IRB70_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632820.1"
                     /translation="MVQLVDLARCVSF"
     gene            11218..12600
                     /gene="dosC"
                     /locus_tag="IRB70_002933"
     CDS             11218..12600
                     /gene="dosC"
                     /locus_tag="IRB70_002933"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DosC"
                     /protein_id="HBC0632821.1"
                     /translation="MEMYFKRMKDEWTGLVEQADPLIRAKAAEIAVAHAHYLSIEFYR
                     IVRIDPHAEEFLSNEQVERQLKSAMERWIINVLSAQVDDVERLIQIQHTVAEVHARIG
                     IPVEIVEMGFRVLKKILYPVIFSSDYSAAEKLQVYHFSINSIDIAMEVMTRAFTFSDS
                     SASKEDENYRIFSLLENAEEEKERQIASILSWEIDIIYKVLLDSDLGSSLPLSQADFG
                     LWFNHKGRHYFSGIAEVGHISRLIQDFDGIFNQTMRNTRNLNNRSLRVKFLLQIRNTV
                     SQIITLLRELFEEVSRHEVGMDVLTKLLNRRFLPTIFKREIAHANRTGTPLSVLIIDV
                     DKFKEINDTWGHNTGDEILRKVSQAFYDNVRSSDYVFRYGGDEFIIVLTEASENETLR
                     TAERIRSRVEKTKLKAANGEDIALSLSIGAAMFNGHPDYERLIQIADEALYIAKRRGR
                     NRVELWKASL"
     gene            12625..15024
                     /gene="dosP"
                     /locus_tag="IRB70_002934"
                     /gene_synonym="pdeO"
     CDS             12625..15024
                     /gene="dosP"
                     /locus_tag="IRB70_002934"
                     /gene_synonym="pdeO"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416006.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-sensing cyclic-di-GMP phosphodiesterase"
                     /protein_id="HBC0632822.1"
                     /translation="MKLTDADNAADGIFFPALEQNMMGAVLINENDEVMFFNPAAEKL
                     WGYKREEVIGNNIDMLIPRDLRPAHPEYIRHNREGGKARVEGMSRELQLEKKDGSKIW
                     TRFALSKVSAEGKIYYLALVRDASVEMAQKEQTRQLIIAVDHLDRPVIVLDPERHIVQ
                     CNRAFTEMFGYCISEASGMQPDTLLNIPEFPADNRIRLQQLLWKTARDQDEFLLLTRT
                     GEKIWIKASISPVYDVLAHLQNLVMTFSDITEERQIRQLEGNILAAMCSSPPFHEMGE
                     IICRNIESVLNESHVSLYALRNGMPIHWASSSHGTEVQNAQSWSATIRQRDGAPAGIL
                     QIKTSSGAETSAFIERVADISQHMAALALEQEKSRQHIEQLIQFDPMTGLPNRNNLHN
                     YLDDLVDKAVSPVVYLIGVDHIQDVIDSLGYAWADQALLEVVNRFREKLKPDQYLCRI
                     EGTQFVLVSLENDVSNITQIADELRNVVSKPIMIDDKPFPLTLSIGISYDVGKNRDYL
                     LSTAHNAMDFIRKNGGNGWQFFSPAMNEMVKERLVLGAALKEAISNNQLKLVYQPQIF
                     AETGELYGIEALARWHDPLHGHVPPSRFIPLAEEIGEIENIGRWVIAEACRQLAEWRS
                     QNIHIPALSVNLSALHFRSNQLPNQVSDAMQAWGIDGHQLTVEITESMMMEHDTEIFK
                     RIQILRDMGVGLSVDDFGTGFSGLSRLVSLPVTEIKIDKSFVDRCLTEKRILALLEAI
                     TSIGQSLNLTVVAEGVETKEQFEMLRKIHCRVIQGYFFSRPLPAEEIPGWMSSVLPLK
                     I"
     gene            15282..15863
                     /gene="ddpX"
                     /locus_tag="IRB70_002935"
     CDS             15282..15863
                     /gene="ddpX"
                     /locus_tag="IRB70_002935"
                     /EC_number="3.4.13.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine dipeptidase"
                     /protein_id="HBC0632823.1"
                     /translation="MSDTTELVDLAVIFPDLEIELKYACADNITGKAIYQQARCLLHK
                     DAITALAKSISIAQLSGLQLVIYDAYRPQQAQAMLWQACPDPQYVVDVAVGSNHSRGT
                     AIDLTLRDEHGNILDMGAEFDEMHERSHAYHPSVPPAAQRNRLLLNAIMTGGGFVGIP
                     SEWWHFELPQAASYPLLADQFTCFISPGTQHAS"
     gene            15877..17427
                     /locus_tag="IRB70_002936"
     CDS             15877..17427
                     /locus_tag="IRB70_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBC0632824.1"
                     /translation="MKRSISFRPTLLAIVLATTMPVAHAAVPKDMLVIGKAADPQTLD
                     PAVTIDNNDWTVTYPSYQRLVQYKTDGDKGSTDVEGDLASSWKASDDQKEWTFTLKND
                     AKFADGTPVTAEAVKLSFERLLKIGQGPAEAFPKDLKIDAPDEHTVKFTLSQPFAPFL
                     YTLANDGASIINPAVLKEHAADDARGFLAQNTAGSGPFMLKSWQKGQQLVLVPNPHYP
                     GNKPNFKRVSVKIIGESASRRLQLSRGDIDIADALPVDQLNALKQENKVNVAEYPSLR
                     VTYLYLNNSKAPLNQADLRRAISWSTDYQGMVNGILSGNGKQMRGPIPEGMWGYDATA
                     MQYNHDETKAKAEWDKVTSKPTSLTFLYSDNDPNWEPIALATQSSLNKLGINVKLEKL
                     ANATMRDRVGKGDYDIAIGNWSPDFADPYMFMNYWFESDKKGLPGNRSFYENSEVDKL
                     LRNALATTDQTQRTRDYQQAQKIVIDDAAYVYLFQKNYQLAMNKEVKGFVFNPMLEQV
                     FNINTMSK"
     gene            17429..18451
                     /locus_tag="IRB70_002937"
     CDS             17429..18451
                     /locus_tag="IRB70_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0632825.1"
                     /translation="MTFWSILRQRCWGLVLVVAGVCVITFIISHLIPGDPARLLAGDR
                     ASDAIVENIRQQLGLDQPLYVQFYRYVSDLFQGDLGTSIRTGRPVLEELRIFFPATLE
                     LAFCALLLALLIGIPLGILSAVWRNRWLDHLVRIMAITGISTPAFWLGLGVIVLFYGH
                     LQILPGGGRLDDWLDPPTHVTGFYLLDALLEGNGEVFFNALQHLILPALTLAFVHLGI
                     VARQIRSAMLEQLSEDYIRTARASGLPGWYIVLCYALPNALIPSITVLGLALGDLLYG
                     AVLTETVFAWPGMGAWVVTSIQALDFPAVMGFAVVVSFAYVLVNLVVDLLYLWIDPRI
                     GRGGGE"
     gene            18448..19344
                     /locus_tag="IRB70_002938"
     CDS             18448..19344
                     /locus_tag="IRB70_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D,D-dipeptide ABC transporter permease"
                     /protein_id="HBC0632826.1"
                     /translation="MMLSEETSAVRPQKQTRFNGAKLVSMLKGSPLTVTGAVIIVLML
                     LMMIFSPWLATHDPNAIDLTARLLPPSAAHWFGTDEVGRDLFSRVLVGSQQSILAGLV
                     VVAIAGMMGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALAAALGPSLFNAM
                     LAIAIVRIPFYVRLARGQTLVVRQYTYVQAAKTFGASRWHLINWHILRNSLPPLIVQA
                     SLDIGSAILMAATLGFIGLGAQQPSAEWGAMVANGRNYVLDQWWYCAFPGAAILLTAV
                     GFNLFGDGIRDLLDPKAGGKQS"
     gene            19341..20327
                     /locus_tag="IRB70_002939"
     CDS             19341..20327
                     /locus_tag="IRB70_002939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0632827.1"
                     /translation="MTQPVLDIQQLHLSFPGFNGDVHALNNVSLKINRGEIVGLVGES
                     GSGKSVTAMLIMRLLPTGSYCVHRGHISLLGEDVLNAREKQLRQWRGARVAMIFQEPM
                     TALNPTRRIGLQMMDVIRHHQPISRREARAKAIALLEEMQIPDAVEVMSRYPFELSGG
                     MRQRVMIALAFSCEPQLIIADEPTTALDVTVQLQVLRLLKHKARASGTAVLFISHDMA
                     VVSQLCDSVYVMYAGSVIESGVTADVIHHPRHPYTIGLLQCAPEHGIPRQPLPAIPGT
                     VPNLTHLPDGCAFRDRCYAAGAQCENVPALTACGDNNHRCACWYPQQEVISV"
     gene            20320..21246
                     /locus_tag="IRB70_002940"
     CDS             20320..21246
                     /locus_tag="IRB70_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0632828.1"
                     /translation="MSDTLLTLRDVHINFPARKNWLGKTTEHVHAINGIDLQIRRGET
                     LGIVGESGCGKSTLAQLLMGMLQPSHGQYIRSGSQRIMQMVFQDPLSSLNPRLPVWRI
                     ITEPLWIAKRSSEQQRRALAEELAVQVGIRPEYLDRLPHAFSGGQRQRIAIARALSSQ
                     PDVIVLDEPTSALDISVQAQILNLLVTLQENRGLTYVLISHNVSVIRHMSDRVAVMYL
                     GQIVELGDAQQVLTAPAHPYTRLLLDSLPAIDKPLEEEWALRKTDLPGNRTLPQGCFF
                     RERCPLATHGCKVRQSLTIREDGREIRCWRAL"
     gene            complement(21302..21733)
                     /gene="osmC"
                     /locus_tag="IRB70_002941"
     CDS             complement(21302..21733)
                     /gene="osmC"
                     /locus_tag="IRB70_002941"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin OsmC"
                     /protein_id="HBC0632829.1"
                     /translation="MTIHKKGQAHWEGDIKRGKGTVSTESGVLNQQPYGFNTRFEGEK
                     GTNPEELIGAAHAACFSMALSLMLGEAGFTPTSIDTTADVSLDKVDAGFAITKIALKS
                     EVAVPGIDASTFDGIIQKAKAGCPVSQVLKAEITLDYQLKS"
     gene            22078..22293
                     /gene="bdm"
                     /locus_tag="IRB70_002942"
     CDS             22078..22293
                     /gene="bdm"
                     /locus_tag="IRB70_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310112.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm-dependent modulation protein"
                     /protein_id="HBC0632830.1"
                     /translation="MFTYYQAENSTAEPALVNAIEQGLRAEHGVVTEDDILMELTKWV
                     EASDNDILSDIYQQTINYVVSGQHPTL"
     gene            22395..22532
                     /gene="sra"
                     /locus_tag="IRB70_002943"
     CDS             22395..22532
                     /gene="sra"
                     /locus_tag="IRB70_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stationary-phase-induced ribosome-associated
                     protein"
                     /protein_id="HBC0632831.1"
                     /translation="MKSNRQARHILGLDHKISNQRKIVTEGDKSSVVNNPTGRKRPAE
                     K"
     gene            22689..24386
                     /gene="maeA"
                     /locus_tag="IRB70_002944"
     CDS             22689..24386
                     /gene="maeA"
                     /locus_tag="IRB70_002944"
                     /EC_number="1.1.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707611.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase"
                     /protein_id="HBC0632832.1"
                     /translation="MEPKTKKQRSLYIPYAGPVLLEFPLLNKGSAFSMEERRNFNLLG
                     LLPEVVETIEEQAERAWIQYQGFKTEIDKHIYLRNIQDTNETLFYRLVNNHLDEMMPV
                     IYTPTVGAACERFSEIYRRSRGVFISYQNRHNMDDILQNVPNHNIKVIVVTDGERILG
                     LGDQGIGGMGIPIGKLSLYTACGGISPAYTLPVVLDVGTNNQQLLNDPLYMGWRNPRI
                     TDDEYYEFVDEFIQAVKQRWPDVLLQFEDFAQKNAMPLLNRYRNEICSFNDDIQGTAA
                     VTVGTLIAASRAAGGQLSEKKIVFLGAGSAGCGIAEMIIAQTQREGLSEEAARQKVFM
                     VDRFGLLTDKMPNLLPFQTKLVQKRENLSDWDTDSDVLSLLDVVRNVKPDILIGVSGQ
                     TGLFTEEIIREMHKHCPRPIVMPLSNPTSRVEATPQDIIAWTEGNALVATGSPFNPVV
                     WKDKIYPIAQCNNAFIFPGIGLGVIASGASRITDEMLMSASETLAQYSPLVLNGEGLV
                     LPELKDIQKVSRAIAFAVGKMAQQQGVAVKTSAEALQQAIDDNFWQAEYRDYRRTSI"
     gene            24520..25530
                     /gene="adhP"
                     /locus_tag="IRB70_002945"
     CDS             24520..25530
                     /gene="adhP"
                     /locus_tag="IRB70_002945"
                     /EC_number="1.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310109.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase AdhP"
                     /protein_id="HBC0632833.1"
                     /translation="MKAAVVTKDHHVDVTDKTLRSLKHGEALLKMECCGVCHTDLHVK
                     NGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETL
                     CRSVKNAGYSVDGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTYKAVKLSKIR
                     PGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINSRTEDA
                     AKIVQEKTGGAHAAVVTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDIPRLVLDG
                     IEVVGSLVGTRQDLTEAFQFAAEGKVVPKVALRPLTDINTIFTEMEEGKIRGRMAIDF
                     RR"
     gene            25676..25960
                     /locus_tag="IRB70_002946"
     CDS             25676..25960
                     /locus_tag="IRB70_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415994.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HigA family addiction module antidote protein"
                     /protein_id="HBC0632834.1"
                     /translation="MKMANHPRPGDIIQESLDELNVSLREFARAMEIAPSTASRLLTG
                     KAALTPEMAIKLSVVIGSSPQMWLNLQNAWSLAEAEKTVDVSRLRRLVTQ"
     gene            complement(26011..26664)
                     /gene="fdnI"
                     /locus_tag="IRB70_002947"
     CDS             complement(26011..26664)
                     /gene="fdnI"
                     /locus_tag="IRB70_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit gamma"
                     /protein_id="HBC0632835.1"
                     /translation="MSKSKMIVRTKFIDRACHWTVVICFFLVALSGISFFFPTLQWLT
                     QTFGTPQMGRILHPFFGIAIFVALMFMFVRFVHHNIPDKKDIPWLLNIVEVLKGNEHK
                     VADVGKYNAGQKMMFWSIMSMIFVLLVTGVIIWRPYFAQYFPMQVVRYSLLIHAAAGI
                     ILIHAILIHMYMAFWVKGSIKGMIEGKVSRRWAKKHHPRWYREIEKAEAKKESEEGI"
     gene            complement(26657..27541)
                     /gene="fdnH"
                     /locus_tag="IRB70_002948"
     CDS             complement(26657..27541)
                     /gene="fdnH"
                     /locus_tag="IRB70_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase N subunit beta"
                     /protein_id="HBC0632836.1"
                     /translation="MAMETQDIIKRSATNSITPPSQVRDYKAEVAKLIDVSTCIGCKA
                     CQVACSEWNDIRDEVGHCVGVYDNPADLSAKSWTVMRFSETEQNGKLEWLIRKDGCMH
                     CEDPGCLKACPSAGAIIQYANGIVDFQSENCIGCGYCIAGCPFNIPRLNKEDNRVYKC
                     TLCVDRVSVGQEPACVKTCPTGAIHFGTKKEMLELAEQRVAKLKARGYEHAGVYNPEG
                     VGGTHVMYVLHHADQPELYHGLPKDPKIDTSVNLWKGALKPLAAAGFIATFAGLIFHY
                     IGIGPNKEVDDDEEEHHE"
     gene            complement(27554..30601)
                     /gene="fdnG"
                     /locus_tag="IRB70_002949"
     CDS             complement(27554..30601)
                     /gene="fdnG"
                     /locus_tag="IRB70_002949"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(30014..30016),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HBC0632837.1"
                     /translation="MDVSRRQFFKICAGGMAGTTVAALGFAPKQALAQARNYKLLRAK
                     EIRNTCTYCSVGCGLLMYSLGDGAKNAREAIYHIEGDPDHPVSRGALCPKGAGLLDYV
                     NSENRLRYPEYRAPGSDKWQRISWDEAFSRIAKLMKADRDANFIEKNEQGVTVNRWLS
                     TGMLCASGASNETGMLTQKFARSLGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANVVMVMGGNAAEAHPVGFRWAMEAKNNNDATLIVVDPRFTRTASVADIYAPIR
                     SGTDITFLSGVLRYLIENNKINAEYVKHYTNASLLVRDDFAFEDGLFSGYDAEKRQYD
                     KSSWNYQFDENGYAKRDETLTHPRCVWNLLKAHVSRYTPDVVENICGTPKADFLKVCE
                     VLASTSAPDRTTTFLYALGWTQHTVGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSTSLPGYLTLPSEKQVDLQSYLEANTPKATLADQVNYWSNYPKFFVSL
                     MKSFYGDAAQKENNWGYDWLPKWDQTYDVIKYFNMMDEGKVTGYFCQGFNPVASFPDK
                     NKVVSCLSKLKYMVVIDPLVTETSTFWQNHGESNDVDPASIQTEVFRLPSTCFAEEDG
                     SIANSGRWLQWHWKGQDAPGEARNDGEILAGIYHHLRELYQAEGGKGVEPLMKMSWNY
                     KQPHEPQSDEVAKENNGYALEDLYDANGVLIAKKGQLLSSFAHLRDDGTTASSCWIYT
                     GSWTEQGNQMANRDNSDPSGLGNTLGWAWAWPLNRRVLYNRASADINGKPWDPKRMLI
                     QWNGSKWTGNDIPDFGNAAPGTPTGPFIMQPEGMGRLFAINKMAEGPFPEHYEPIETP
                     LGTNPLHPNVVSNPVVRLYEQDALRMGKKEQFPYVGTTYRLTEHFHTWTKHALLNAIA
                     QPEQFVEISETLAAAKGINNGDRVTVSSKRGFIRAVAVVTRRLKPLNVNGQQVETVGI
                     PIHWGFEGVARKGYIANTLTPNVGDANSQTPEYKAFLVNIEKA"
     gene            30833..31714
                     /gene="yddG"
                     /locus_tag="IRB70_002950"
     CDS             30833..31714
                     /gene="yddG"
                     /locus_tag="IRB70_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415990.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid efflux DMT transporter YddG"
                     /protein_id="HBC0632838.1"
                     /translation="MTRQKATLIGLIAIVLWSTMVGLIRGVSEGLGPVGGAAAIYSLS
                     GLLLIFTVGFPRIRQIPKGYLLAGCLLFVSYEICLALSLGYAATRHQAIEVGMVNYLW
                     PSLTILFAILFNGQKTNWLIVPGLLLALVGVCWVLGGDNGLHYDEIINNITTSPLSYF
                     LAFIGAFIWAAYCTVTNKYARGFNGITVFVLLTGASLWVYYFLTPQPEMVFSTPVMIK
                     LISAAFTLGFAYAAWNVGILHGNVTIMAVGSYFTPVLSSALAAVLLSAPLSFSFWQGA
                     LMVCGGSLLCWLATRRG"
BASE COUNT         8057 a         7906 c         7927 g         7908 t
ORIGIN      
        1 tgaacttgct gaactggctg cggttatcga tcgcttgtat gagttccatc aactcaccga
       61 acagcgccct acgaataagc ctaaaaattg ccaacatgcg gtacaagtgg ctgacgcgag
      121 tattcgtact cctgataata agatcatatt agagaacctg aactttcatg ttttgccagg
      181 caaatggcta ttgctgaaag gttactctgg tgcgggaaaa accacactgc ttaaaacatt
      241 atcccactgc tggccgtggt ttaaaggtga tatttcttct cctgctgaca gttggtatgt
      301 gtcacaaaca ccgttaatca aaaccggctt actgaaagag attatttgta aagcacttcc
      361 cctgtccgta gacgataaat cgttgagtga agtactgcat caggttgggc tggggaaatt
      421 ggctacgcgt attcatgacc acgatcgctg gggagatatt ctttccagcg gcgaaaaaca
      481 acgtatcgcc ctggctcgat taattttacg acgtccgaaa tggatatttc ttgacgaaac
      541 tacctctcat cttgaggaac aagaggcaat ccgcttactg cgtttagtgc gagaaaaact
      601 ccccacaagc ggcgtcatta tggttacaca tcaacccggt gtctggaacc tggccgatga
      661 tatttgtgac attagcgcgg ttttataaaa acaataaaag ccctgctgta cggagatata
      721 aataaatgaa gcgagttctt attcctggcg tcattttatg tggcgctgat gtggcgcagg
      781 ccgtcgatga caaaaacatg tacatgcatg tttttgaaga gatgacggtc tatgctcctg
      841 tccctgtacc cgtaaacggc aacacgcatt acaccagtga aagcatcgag cgtttaccga
      901 ccgggaatgg caatatcagc gatctgctga gaaccaaccc tgcggtgcgc atggattcaa
      961 cgcaaagtac ctcgttgaac cagggagata ttcgcccgga aaaaatctct attcacggtg
     1021 cgtcgcccta ccagaatgcc tatttgattg atggcattag tgcaactaat aacctgaacc
     1081 cagcgaatga gtccgatgcc agtagtgcaa ccaatattag cgggatgtca cagggctatt
     1141 atcttgatgt cagcttactg gacaatgtga cgctttatga cagttttgtg ccggttgaat
     1201 tcggtcgctt caatggcggg gtaattgatg caaagatcaa acgcttcaac gctgatgata
     1261 gcagcgtgaa actgggttat cgcactacgc gttcggactg gttaacatcg catatcgatg
     1321 agaataacaa gagcgcattt aatcaaggtt cttcaggaag tacttattac tctccagatt
     1381 ttaaaaagaa cttttatacc ttgtcgttta atcaggaact cgctgataac ttcggcgtta
     1441 ccgccggttt atcgcgccgc cagtctgata tcacccgcgc ggattatgtt tcgaatgacg
     1501 gcattgtcgc cggccgggca cagtataaaa acgttatcga tactgcattg agcaaattta
     1561 cctggtttgc cagcgaccgc tttacccacg atttaacctt aaaatatacc ggctccagcc
     1621 gtgattataa taccagcacc ttcccgcagt ctgatcgcga aatgggtaat aaatcctatg
     1681 gtctggcatg ggatatggat acgcagctcg catgggctaa actacgtacc accgttggtt
     1741 gggatcatat tagtgattat acccgtcacg atcatgacat ctggtacacc gaactttcat
     1801 gtacatatgg tgatattaca gggcgttgca cccgtggcgg attaggacac atttcccagg
     1861 ctgtagataa ttacaccttc aaaacacgcc tggactggca aaaattcacc gtgggtaatg
     1921 tttcgcatca accctacttc ggcgcggaat acatctattc cgatgcatgg actgaacgcc
     1981 ataaccagtc tgaatcctat gtgattaatg ctgccggaaa gaaaactaac cataccattt
     2041 accataaagg taaaggcagc ctgggaattg acaactacac gctgtatatg gcggatcgca
     2101 ttagctggcg taatgtgtca ttaatgcccg gcgtgcggta tgactatgac aactatctgt
     2161 caaaccacaa tatctccccg cgttttatga cggaatggga tatttttgct gatcaaacct
     2221 caatgattac cgcaggttat aaccgttact atggcgggaa tattcttgat atgggattac
     2281 gtgatattcg caatagctgg acggaatcgg tatcaggcaa taaaaccctg acgcgttatc
     2341 aggatttgaa aacgccttat aacgatgaac tggcaatggg cttgcagcaa aaaatcagta
     2401 agaacgttat tgcgcgcgca aactatgttt accgtgaagc gcatgatcaa atcagcaaaa
     2461 gcagtcgtac cgacagcgcg actaaaacca ccattactga atataacaac gacggtaaaa
     2521 ccaaaacgca ttcgttcaac ctcagttttg aactggccga acccctgcat atcagccagg
     2581 tagatattaa cccgcaaatt gtctttagct atatcaagag caagggcaac ttgtcgttaa
     2641 acaatggtta tgaggagagc aataccggtg ataaccaggt ggtttataac ggtaatctgg
     2701 tctcttacga tagcgttcca gtggcggatt ttaataatcc attaaagatc tccttaaaca
     2761 tggatttcac gcatcaaccg agcgggttgg tgtgggcgaa tacgctgacc tggcaagaag
     2821 cgcgtaaagc tcgcattatc ctaggtaaga cgaatgcgca atacatcagc gaatattcag
     2881 attacaagca gtatgttgac gaaaaactgg atagcagcct gacctgggac acccgcttgt
     2941 cctggacgcc acaatttctg aaacaacaaa acctgacgtt cagtgccgat attctcaatg
     3001 tactggatag caaaaccgct gttgatacaa cgaataccgg tgtggcgacc tacgccagtg
     3061 gccgtacttt ctggcttgat gtcagcatga aattttaata gttcggattt tacttaaccg
     3121 ggtaaattcg cccggttttc gcatggagat aattatgaga aacctctgtt tcttactgac
     3181 gttagtggca actctgttgc tccccgggcg actgattgcc gccgccttac cgcaggatga
     3241 aaagttaatt accgggcaac tggacaatgg cttgcgatat atgatttatc cgcatgctca
     3301 accaaaggat caggtaaatt tatggctgca aattcatacc ggttcattgc aggaagagga
     3361 caatgagcgc ggcgtggctc attttgtaga acatatgatg tttaacggca caaaaacatg
     3421 gccgggtaat aaagtcatcg aaacatttga gtcaatgggc ctgcgttttg gtcgcgatgt
     3481 taatgcctat accagctatg acgaaacagt gtatcaggtg agtttgccga ctacgcagaa
     3541 acaaaatctg caacaagtga tggcaatctt cagtgaatgg agtaatgccg caacctttga
     3601 aaaactcgaa gtagacgctg aacgcggcgt aattactgag gaatggcgtg cccatcagga
     3661 tgcaaaatgg cgcacctctc aggcgcgccg ccctttcctg ctggcaaata cccgtaattt
     3721 agaccgtgaa cctatcggcc tgatggatac cgtcgccacg gtcacaccgg cacaattgcg
     3781 ccaattttat caacgctggt atcaaccaaa taatatgacc tttattgtgg tcggcgatat
     3841 cgacagtaaa gaagcgctgg cgctgataaa ggataattta agtaagcttc cggctaacaa
     3901 agcagctgaa aatcgcgtct ggccgacaaa agccgaaaac cacctgcgct ttaatatcat
     3961 caatgataaa gaaaaccggg tgaacggcat cgcactctat tatcgcctgc caatggtgca
     4021 agtgagcgat gagcaaagct ttatcgaaca agctgaatgg agcatgttag ttcagctgtt
     4081 caaccaacgt ctgcaagaac gcatacagtc gggcgagttg aagactattt ctggcggcac
     4141 tgcgcgcagc gtcaaaattg cacccgatta tcagtcgctg tttttccgtg taaatgcaca
     4201 agacgataat atgcaggatg ctgcgaatgc attaatggca gagttggcaa ccattgatca
     4261 gcatggcttt tctgctgaag aactcgatga tgttaaatct acccgcctta cctggctgaa
     4321 aaatgcggtt gatcagcaag ctgagcgtga tttacgtatg ctgaccagtc gcctggcatc
     4381 cagctcatta aataatacgc cgttcttgtc gccggaagag acatatcaac tttcgaaacg
     4441 tctgtggcag caaattaccg tgcaaagtct ggcggaaaaa tggcagcagt taagaaagaa
     4501 ccaggacgca ttttgggagc aaatggtaaa caatgaagtt gccgccaaaa aagcattgtc
     4561 tcctgcggct atcctggcgc tggaaaaaga gtacgccaac aaaaagctgg cagcttacat
     4621 cttcccaggc agaaatttat cgttaacagt agacgctgac ccacaggcgg aaattagcag
     4681 caaagaaacg ctggctgaga atctgacatc attaacactt tccaatggtg ccaaggttat
     4741 tctggcaaaa tccgcgggtg aagagcaaaa gctacaaatt actgccgtat ctaataaagg
     4801 cgatttaagt ttccctgcgc agcaaaaatc acttatcgcg ctggcaaata aagcagtaag
     4861 cggaagcggc gttggtgaac tctcctcttc cagcctgaaa cgctggagtg cggaaaactc
     4921 ggtaaccatg agcagtaaag tcagtggcat gaatacattg ctctctgtta gcgcgcggac
     4981 taataaccct gaacctggtt tccagttgat taaccagcga atcacccaca gcacgattaa
     5041 cgataatatt tgggcatcgc tacaaaatgc tcaaattcag gcgttgaaaa cgctcgacca
     5101 gcgtccagcg gagaaattcg cccagcagat gtatgagacg cgctatgctg atgaccgcac
     5161 gaaattactg caagaaaatc agattgcaca gtttactgcc gcagatgcgc tggctgccga
     5221 tcgccagttg ttttcatctc ctgcggatat cacgtttgtc attgtcggta atgtcgcaga
     5281 agacaaactc gtggcgttaa ttacgcgtta cttaggatca atcaaacact ctgattcgtc
     5341 attagccgca ggtaaaccat taactcgcgc gacggacaac gcatcggtta ctgtaaaaga
     5401 acaaaatgaa cctgtggcac aggtttcaca gtggaagcgt tatgattccc ggacacctgt
     5461 aaatctggcg acgcgtatgg cgctcgatgc ttttaacgtc gcactggcaa aagatctacg
     5521 cgttaatatt cgtgaacagg catctggagc atacagcgtt tcttctcgtc tctcggttga
     5581 tcctcaggcc aaagatatca gtcatttgct ggcttttact tgtcaaccag aacgacatga
     5641 tgaactgtta acgttagcga atgaagtgat ggttaagcgt ctggctaaag ggatcagtga
     5701 gcaagaactg aatgaatacc agcaaaacgt tcagcgcagc ctcgatatcc aacagcgtag
     5761 cgttcaacaa ttagcgaaca ctattgtaaa tagtcttatt caatatgacg atcctgcagc
     5821 atggactgag caggagcaat tgttgaaaca aatgacggta gagaatgtta acactgccgt
     5881 taaacaatat ctttctcatc cggtaaatac ttatgccggg gtattattgc caaaataatc
     5941 acagccccgt caacacatcg ttggcgggga ttttagcaat attcgctatt tttatgtaat
     6001 aattttataa atgcgttcaa agtaaataac cgcgtactaa taatgatatt ttaaggtctg
     6061 atttttacgt gataattcag gaggcacaga atgcacataa aaataacagc ataaaacacc
     6121 ttgccaccac ccaatagctc cctactatat tgtttttcaa tgaaaaaata ttattcacgc
     6181 aatatctcac gataaataac attaggattt tgttatttaa acacgagtcc tttgcacttg
     6241 cttactttat cgataaatcc tactttttta atgcgatcca atcattttaa ggagtttaaa
     6301 atggataaga agcaagtaac ggatttaagg tcggaactac tcgattcacg ttttggtgca
     6361 aagtctattt ccactatcgc agaatcaaaa cgttttccgc tgcacgaaat gcgcgacgat
     6421 gtcgcatttc agattatcaa tgacgaatta tatcttgatg gcaacgctcg tcagaacctg
     6481 gccactttct gccagacctg ggacgacgaa aatgtccaca agttgatgga tttatccatt
     6541 aacaaaaact ggatcgacaa agaagaatat ccgcaatctg cagccatcga cctgcgttgc
     6601 gtaaacatgg ttgccgatct gtggcatgcg cctgcaccga aaaatggtca ggccgttggc
     6661 accaacacca ttggttcttc cgaggcctgt atgcttggcg ggatggcgat gaaatggcgt
     6721 tggcgcaagc gtatggaagc tgcaggtaag ccaacggata aaccaaacct ggtgtgcggt
     6781 ccggtacaaa tctgctggca taaattcgcc cgctactggg atgtggagtt gcgtgagatc
     6841 cctatgcgcc ccggtcagtt gtttatggac ccgaaacgca tgattgaagc ctgcgacgaa
     6901 aataccatcg gcgtggtgcc gactttcggc gtgacctata ccggtaacta tgagttcccg
     6961 cagccgctgc acgatgcgct ggataaattc caggccgaca ccggtatcga catcgacatg
     7021 cacatcgacg ccgccagcgg tggcttcctg gcaccgttcg tcgccccgga tatcgtctgg
     7081 gacttccgcc tgccgcgtgt gaaatcgatc agtgcttcag gccataaatt cggtctggct
     7141 ccgctaggct gcggctgggt tatctggcgt gatgaagaag cgctgccgca ggaactggtg
     7201 ttcaacgttg actatctcgg tggtcagatt gggactttcg ccatcaactt ctcccgcccg
     7261 gcgggtcagg tgattgcaca gtactatgaa ttcctgcgcc tcggtcgtga aggctatacc
     7321 aaagtacaga acgcttccta ccaggttgct gcctatctgg cggatgaaat cgccaaactg
     7381 gggccgtatg agttcatctg taccggtcgc ccggacgaag gcatcccagc ggtttgcttc
     7441 aaactgaaag atggtgaaga tccgggatac accctctacg acctctctga acgtctgcgt
     7501 ctgcgcggct ggcaggttcc ggccttcact ctcggcggtg aagccactga catcgtggtg
     7561 atgcgcatta tgtgtcgtcg cggcttcgaa atggactttg ctgaactgtt gctggaagac
     7621 tacaaagcct ccctgaaata tctcagcgat cacccgaaac tgcagggtat tgcccagcag
     7681 aacagcttta aacatacctg ataacgttta acggtaacgg tgtcccgaaa cacacccgtt
     7741 tcgggacaat ttccaaagtc tgttcactgg cattagcaac ggaaaatatt gttctgaata
     7801 cgcttcagaa caaaacaggt gcggttccga caggaatacc gttttagggg gataatatgg
     7861 ctacatcagt acagacaggt aaagctaagc agctcacatt actcggattc tttgccataa
     7921 cggcatcgat ggtaatggct gtttatgaat accctacctt cgcaacatcg ggcttttcat
     7981 tagtcttctt cctgctatta ggcgggattt tatggtttat tcccgtggga ctttgtgctg
     8041 cggaaatggc taccgtcgac ggctgggaag aaggtggcgt cttcgcctgg gtatcaaata
     8101 ctctggggcc gagatgggga tttgcagcga tctcatttgg ctatctgcaa atcgccattg
     8161 gttttattcc gatgctctat ttcgtgttag gggcactctc ctacatcctg aaatggccag
     8221 cgctgaatga agaccccatt accaaaacta ttgcagcact catcattctt tgggcgctgg
     8281 cattaacgca gtttggtggc acgaaataca cggcgcgaat tgctaaagtt ggcttcttcg
     8341 ccggtatcct gttacctgca tttattttga tcgcattagc ggctatttat ctgcactccg
     8401 gtgcccccgt tgctatcgaa atggatgcga agaccttctt ccctgacttc tctaaagtgg
     8461 gcactctggt tgtatttgtt gccttcattt tgagttatat gggcgttgaa gcttccgcaa
     8521 cccacgtcaa tgaaatgagc aaccccgggc gcgactatcc actggctatg ttactgctga
     8581 tggtggcggc aatctgctta agctctgttg gcggtttgtc tattgcgatg gtcattccgg
     8641 gtaatgaaat caacctctcc gcaggggtaa tgcaaacctt taccgttctg atgtcacatg
     8701 tggcaccgga aattgagtgg acggttcgcg tgatctccgc actgctgttg ctgggtgttc
     8761 tggcggaaat cgcttcctgg attgttggtc cttctcgcgg gatgtatgtc acagcgcaga
     8821 aaaacctgct gccagcggca ttcgctaaaa tgaacaaaaa tggcgtaccg gtaacgctgg
     8881 tcatttcgca gttggtgatt acttctatcg cgttgatcat cctcaccaat accggtggcg
     8941 gtaacaacat gtccttcctg atcgcactgg cgctgacggt ggtgatttat ctgtgtgctt
     9001 atttcatgct gtttattggc tacattgtgt tggttcttaa acatcctgac ttaaaacgca
     9061 catttaatat ccctggtggt aaaggggtga aactggtcgt ggctattgtc ggtctgctga
     9121 cttcaattat ggcgtttatt gtttccttcc tgccgccgga taacatccag ggtgactcta
     9181 ctgatatgta tgttgaatta ctggtcgtga gtttcctggt ggtacttgcc ctgcccttta
     9241 ttctctatgc tgttcatgat cgtaaaggca aagggaatac cggcgttact ctggagccaa
     9301 tcaacagtca gaacgcacca aaaggtcact tcttcctgca cccgcgtgca cgttcaccac
     9361 actatattgt gatgaatgac aagaaacact aaccatgtct gaatggttat aagataaggg
     9421 agcgataatt catcgctccc tttttcgtgc ttgctgtcgt attgacttaa ccgggataag
     9481 tacgagaatg agcgcacatc tgtttaccgg aaaccagcac atatggatat ctgctcccga
     9541 aacgagaaat tagcgattag aagaccagcg atactggttg cactggcact tttactgtgt
     9601 agttgtaaaa gcacgcctcc agagtccatg gtgacaccac cagcgggttc aaagccacca
     9661 gccacgacgc aacaatcgtc acaaccgatg cgtggcatct ggctggccac ggtgtctcgc
     9721 ctcgactggc caccgctttc ctcggttaac attagtaacc ccaccagccg ggcccgtgta
     9781 caacaacagg cgatgatcga caaactggat catctgcaac gtctcggcat aaacacggtc
     9841 ttttttcagg tcaagccgga tggtaccgcc ctgtggccat cgaaaatttt gccgtggtcc
     9901 gatcttatga ccggtaagat tggtgaaaat ccgggttacg atccgctgca attcatgctc
     9961 gacgaagccc acaagcgtgg gatgaaagta cacgcatggt ttaaccccta tcgcgtatcg
    10021 gttaatacga agcccggtac tatcagggaa ctgaatagca ccctgtctca acaaccggcc
    10081 agcgtctatg tgcaacaccg cgactggatc agaacgtccg gcgatcgctt tgtcctcgac
    10141 ccgggcatcc ctgaggttca ggactggatc acatcaatag tcgcagaagt ggtttcccgc
    10201 tatccggtag atggcgtgca gtttgacgac tatttctata ctgagtcacc agcttcacgg
    10261 ctaaatgata acgaaacgta ccgcaaatac ggcggcgcat ttgcgtcaaa agcagactgg
    10321 cggcgcaaca atactcagca gttaattgcg aaggtatcgc acaccattaa aagcattaag
    10381 ccggaagtcg aatttggcgt tagcccggca ggcgtgtggc gtaaccgatc acacgatccg
    10441 ctcggttccg atacccgagg cgcggcagcc tatgacgaat cctacgctga tacccgtcga
    10501 tgggtggaac aagggttgct ggattacatt gctccccaaa tttactggcc gttctcacgg
    10561 agtgccgcac gttatgacgt gttggcaaaa tggtgggcgg atgtcgttaa accgaccagg
    10621 acccgcctgt atatcggtat cgccttctat aaagtgggtg aaccttcaaa gatagagcca
    10681 gactggatga ttaacggcgg cgtaccggaa ctgaaaaagc agctcgatct taacgatgcc
    10741 gtgccagaaa ttagcggcac aatcttgttc cgtgaggact atctgaataa gccacagact
    10801 caacaagcgg tcagctatct gcaaagtcgt tggggcagtt aaactcccat tcttactttg
    10861 taacaagccg gtgctttccc cccggcttgt taccctcttg aaatatccca ctagtaatca
    10921 tgcttactta agtcaaatta actacgcaat taaccacact tagttaaaca gtcataaatc
    10981 ccctaataaa aatgtatgaa catgaaaaaa catacgatat tcgctgtcac cgaaaaataa
    11041 ttacgatggg ctatactctt ctgaagaaca gtagcgtaga ttgaaactgt cctaagtcgc
    11101 ttatttgttt tcagtatatc ttcatatttc aggagagtat ggtgcagtta gtcgatctcg
    11161 cacgttgcgt ttcgttttga ttccgtctgc tttcccagcc ttataagggt gtgaattatg
    11221 gagatgtatt ttaaaagaat gaaagatgag tggaccgggc ttgtcgaaca agcagatccg
    11281 ctcattcgtg ctaaagccgc ggaaattgcc gttgcgcatg ctcattatct gagtattgag
    11341 ttttatcgaa ttgtccgtat cgacccacat gccgaagaat tcttgagtaa tgaacaagtt
    11401 gagcggcagt tgaaaagtgc gatggaacgc tggattatta acgtgctttc tgcccaggtt
    11461 gacgatgtcg aaaggctaat acaaatccag cataccgtcg cggaagtgca tgcccgcata
    11521 ggaattccgg tagaaattgt cgagatgggg tttcgggtgc tgaaaaaaat cctctatccg
    11581 gtcatcttct cttcggatta ttccgccgca gaaaaacttc aggtctacca tttctctatt
    11641 aacagtattg atatcgctat ggaagtgatg acccgcgcgt ttacctttag tgacagtagt
    11701 gcctcaaagg aagatgaaaa ctatcgtatc ttctcgttac tggaaaatgc cgaagaagaa
    11761 aaagaacggc aaatagcctc aatactttca tgggaaatag atattatcta taaagtcctg
    11821 ctggattctg atttaggcag tagtttgcct ttaagccagg ctgattttgg cctgtggttt
    11881 aaccataaag gtcgacatta ttttagcggc attgccgaag tgggccatat ctcccgtctg
    11941 attcaggatt tcgacggtat tttcaatcaa accatgcgta acaccaggaa tttgaataac
    12001 agaagtttac gggtgaaatt tttattacag ataagaaata ccgtatcgca aattattacc
    12061 ttgctgcgtg aattgtttga agaagtatcg cgccacgaag tcggtatgga tgtcctgacg
    12121 aaattactta accgtcgttt cctgccgacg atcttcaaac gcgaaattgc ccatgccaac
    12181 cggaccggta caccgctgtc agtgctgatt attgacgttg ataaattcaa agagatcaac
    12241 gatacgtggg gccataacac tggcgatgaa attctgcgta aagtctctca ggccttttat
    12301 gacaacgtcc gcagtagtga ttatgttttc cgctacggtg gcgatgaatt tatcattgtt
    12361 ttgactgaag cttcggaaaa cgaaacgtta cgtaccgcag aacgtattcg cagtcgggtg
    12421 gagaaaacca aactgaaagc cgcaaacggc gaggatattg ccctctcact ttccatcggt
    12481 gccgccatgt ttaatggtca tcctgactat gagcgcctca ttcaaatagc cgatgaagct
    12541 ctgtatatcg ccaaaagacg aggtagaaac cgtgttgaac tctggaaagc cagtctttag
    12601 atgcgtcagg atgcagaggt aattatgaag ctaaccgatg cggataatgc cgccgatggc
    12661 atttttttcc ccgcccttga gcaaaatatg atgggtgcgg tgttaattaa cgaaaatgat
    12721 gaagtgatgt ttttcaaccc cgccgcagag aagctctggg ggtacaaacg tgaagaagtc
    12781 attggcaata acattgatat gctgattccg cgggatttgc gtcctgcgca tcctgaatat
    12841 attcgtcata accgtgaagg cggtaaagcg cgcgtcgagg ggatgagtcg ggagctgcag
    12901 ctggagaaaa aagacggcag taaaatctgg acccgttttg cgctatcgaa agtgagcgcc
    12961 gagggtaaaa tttattacct ggcgctggta cgggatgcca gcgtagaaat ggcgcaaaaa
    13021 gaacagaccc gacaattgat tattgccgtt gaccatctcg accgaccggt gattgtcctc
    13081 gatccggaac gccatattgt gcagtgcaat cgcgcattta ccgaaatgtt tggttactgc
    13141 attagcgaag ccagcggtat gcagcccgat acactcctga acattcctga attccctgcc
    13201 gataaccgca ttcgtttaca acagttgcta tggaaaaccg cccgcgatca ggacgaattt
    13261 ctgctattga cgcgcaccgg tgaaaaaatc tggattaaag cctctatcag cccggtttat
    13321 gacgtgctcg cgcatctgca gaacctggta atgaccttct cggatatcac cgaagaacgg
    13381 caaatccgcc agcttgaagg caatattctc gccgccatgt gcagcagccc gccatttcat
    13441 gaaatggggg aaatcatttg tcgtaacatc gaatctgtac tcaacgaatc gcatgtttcg
    13501 ctgtacgcgc tgcgcaacgg gatgccgata cactgggcgt catcttcgca cggtacagaa
    13561 gttcaaaatg cgcaaagctg gtcagcgacc attcgtcagc gtgatggcgc gccggcgggg
    13621 atcctgcaaa ttaaaacctc gtcaggagca gaaaccagcg cctttatcga acgcgtggca
    13681 gatatcagcc agcatatggc cgcgctggcg ctggaacagg aaaaaagccg tcagcatatt
    13741 gaacaactca tccaatttga tccgatgacc ggtctgccaa atcgcaataa cctgcacaat
    13801 tacctcgatg acctggtcga caaagccgtc tctccagtgg tgtatctcat cggtgttgac
    13861 catattcagg atgtgattga tagccttggc tatgcgtggg ccgatcaggc attgctggaa
    13921 gtggtcaatc gctttcgtga aaaactcaaa ccggatcaat atctctgtcg tatcgaaggt
    13981 acgcagtttg tcctcgtgag cctcgaaaac gacgtcagta acattacgca gatcgccgat
    14041 gagctacgga atgtggtcag caagccgata atgattgacg ataaaccatt cccgctcacc
    14101 ttgagcattg gcatcagcta cgacgtgggt aaaaaccgcg attacctgct ctccactgct
    14161 cacaatgcaa tggattttat tcgcaaaaat ggcggtaacg gctggcagtt cttcagcccg
    14221 gcgatgaacg aaatggtaaa agagcgtttg gttttaggcg cggcgctgaa agaagcaatt
    14281 agcaataacc aactgaaact ggtttaccag ccacaaatct tcgcagaaac gggtgaactg
    14341 tacggcatcg aagcccttgc tcgctggcac gatcccctgc atggtcatgt gcccccttca
    14401 cggtttattc ctctcgcaga agagatcggt gaaatcgaaa atattggacg ctgggtcatc
    14461 gcggaagctt gccgtcagtt agcagaatgg cgtagccaga atattcatat cccggcgtta
    14521 tccgtgaact tgtcggcgct gcactttcgc agtaatcagc tgcctaatca ggtgtctgat
    14581 gcaatgcaag cctggggtat tgacggccac cagctgacgg tagaaatcac ggaaagcatg
    14641 atgatggaac acgataccga aatctttaag cgcattcaga tcctgcgcga tatgggcgtg
    14701 ggcttatcgg tagatgattt tggcacgggc ttttccggat tatcccgctt agtcagtctt
    14761 ccggtaacgg aaatcaaaat tgacaaaagt tttgtcgatc gttgtctgac ggaaaaacgc
    14821 atccttgcct tacttgaagc cattaccagc attgggcaaa gccttaattt aaccgtcgtg
    14881 gcggaaggcg tcgaaaccaa agagcaattt gagatgctac gcaagatcca ctgtcgcgtt
    14941 attcagggat atttcttttc ccgcccccta cccgccgaag aaattccagg ctggatgagc
    15001 agtgtgttac cgctgaaaat ctgacaaatt cctctcgccc gcactcgcgg gttttccttt
    15061 aacgtgacac tgtcacttaa atactgtgat ttcagctacg attccgggag attccttcct
    15121 taacttcccc tcttgcacca aaactgcact acgctgcaca aatgttgatc aaaagttaaa
    15181 aaatataact ttaagccagc attctggcgc ttatcccggc gtggcatgag atctgcataa
    15241 gcggaaagcg cagcaatttt tgtcttatac aggaaccgtt tatgtcggat accaccgaac
    15301 tggttgattt agccgtgatc ttccctgatc tggagatcga attgaaatac gcctgcgctg
    15361 ataacatcac aggcaaagct atttatcagc aagcgcgttg tctgttacac aaggatgcga
    15421 ttaccgcgct ggcgaaaagt atcagtatcg cccagctgtc aggcttacaa ctggtgattt
    15481 acgatgcgta tcgcccacaa caagcacagg cgatgttgtg gcaagcctgc ccagacccgc
    15541 aatatgttgt tgatgtggcg gtcggttcta atcacagccg tggcacggcg atcgacctga
    15601 cgcttcgtga tgagcacggg aacatactgg atatgggtgc agagttcgat gaaatgcacg
    15661 aacgttccca tgcttatcac ccttccgtcc cgccagctgc tcagcgcaat cggctgttgc
    15721 tgaatgcgat tatgactggc ggtggctttg tcggtatccc gagcgaatgg tggcacttcg
    15781 aattacccca ggcagcgagt tacccacttc tcgctgatca attcacctgt tttatatccc
    15841 ctggcacaca gcacgccagt taatcaggaa actgtcatga agagatcgat atcgtttcgt
    15901 cctacattgc tcgcgatcgt ccttgccaca acaatgccgg ttgcgcacgc cgccgtaccg
    15961 aaagatatgc tggtgatcgg taaagctgcc gacccacaaa ccctcgaccc agcggtgaca
    16021 attgataata acgactggac agtgacctac ccgtcttatc agcgactggt tcagtacaaa
    16081 acggacggtg ataaaggctc aaccgacgtt gaaggcgatc tggcgagtag ctggaaagcg
    16141 tctgacgatc aaaaagagtg gacgttcacc ctgaagaacg acgctaaatt tgccgatggc
    16201 acacccgtca ctgccgaagc agtaaaactc tcttttgagc ggttactaaa aatcggtcag
    16261 gggccagcag aagcatttcc caaagattta aagattgatg ctcccgacga acatacggtg
    16321 aagtttaccc ttagccagcc attcgcaccg ttcctctaca cgctggcgaa tgacggtgca
    16381 tccattatca atccggcggt cttaaaggag catgcggcgg atgatgcccg tggtttcctc
    16441 gcgcaaaata ccgctggctc cggaccgttt atgctgaaaa gctggcaaaa aggtcagcaa
    16501 ttagttctgg tgccaaatcc gcattacccc ggcaataaac cgaatttcaa acgggtatcg
    16561 gtaaaaatta tcggtgaaag tgcttcccgt cgcctgcagc tctcccgtgg cgacattgac
    16621 attgccgatg cgctgccggt ggatcaactc aacgccctga agcaggaaaa caaagtcaac
    16681 gtggcagagt atccgtcact gcgcgtcacc tatctgtatc tgaataacag caaagcgcca
    16741 cttaatcagg cggatctgcg tcgggccatt tcctggtcta ccgattatca gggtatggtt
    16801 aacggcattc tgagtggtaa cggaaaacaa atgcgcggcc cgattccgga aggcatgtgg
    16861 ggatacgatg cgacggcaat gcaatacaac catgacgaaa cgaaagccaa agccgaatgg
    16921 gataaagtga cgagcaaacc caccagcctg acgtttctct attctgataa tgatccgaac
    16981 tgggagccta ttgctctggc gacacaatcc agtctcaaca agctgggcat caatgtgaag
    17041 ctggaaaagc tggcgaacgc caccatgcgc gacagagtgg gtaaaggtga ttacgacatc
    17101 gcgattggca actggagtcc ggattttgcc gacccgtata tgtttatgaa ttactggttt
    17161 gagtccgaca aaaaaggtct gccgggtaac cgctcgttct atgaaaacag tgaggtcgat
    17221 aagttactgc gcaatgcgct agcgaccacc gaccagacgc agcgtacccg ggactaccag
    17281 caggcacaga aaatcgtcat tgatgacgct gcttatgtgt acctgttcca gaaaaactat
    17341 caactggcga tgaacaaaga ggtgaaaggc tttgtgttca atcccatgct ggaacaggtc
    17401 ttcaatatca atactatgag taaataacgt gaccttctgg agtattttac gccaacgctg
    17461 ctgggggctg gtgctcgtgg tggcgggcgt ctgcgtgatt acgtttatta tctcgcacct
    17521 gatccctggc gatccggcgc ggttactggc gggtgaccgc gccagcgatg ctatcgtgga
    17581 aaatattcgc cagcaactgg ggctggacca gccactgtac gtacagtttt accgctacgt
    17641 cagcgatctg tttcagggtg acctgggaac atccattcgt accgggcgtc cggtgctgga
    17701 agagttgcgt atatttttcc cggcgacgct ggaactggca ttttgcgcgc tgctgctggc
    17761 actcctgatt ggcatcccgt tgggcatact ctctgcagtc tggcgaaatc gctggctgga
    17821 tcatctggtg cgaataatgg ccattaccgg aatctccaca cctgcgttct ggcttgggct
    17881 gggcgtcatt gtgctgtttt atggtcatct gcaaattctt cccggcggcg gaaggcttga
    17941 tgactggctg gatccaccaa cgcacgttac cggcttttat ctgctcgatg cgctgcttga
    18001 aggcaacggt gaggtcttct tcaatgcgtt gcaacatctt atcttaccgg cattaacgct
    18061 ggcgttcgtt cacctgggga ttgtcgcccg ccagatccgc tcagctatgc tggaacaatt
    18121 gagtgaagat tacattcgta ccgcccgggc cagcggcttg cccggctggt atatcgtttt
    18181 atgttatgcg ctacccaatg cgttgatccc ctcgattacc gtattgggac tggcgctggg
    18241 cgatttgttg tatggcgcag tgctcaccga aaccgttttt gcctggcccg gaatgggtgc
    18301 atgggtagta acatcaatac aggcgctcga cttcccggca gtgatgggct ttgccgtcgt
    18361 ggtttcattt gcttatgtgc tggtgaacct ggtggtggat ttgctctatt tgtggattga
    18421 tccgcgtatc ggacgtggag gtggtgaatg atgctaagcg aggaaacgtc cgccgtacgc
    18481 ccacaaaaac aaacgcgatt taacggtgca aaactggtat cgatgctgaa aggcagcccg
    18541 ctcaccgtga ccggcgcagt catcattgta ttaatgctat tgatgatgat tttttcaccg
    18601 tggctggcga cgcatgatcc caacgccatt gatttaaccg cccgcctttt gccgccttct
    18661 gcggcgcact ggtttggcac cgatgaagtg ggacgcgatc tgttcagccg cgtactggtc
    18721 ggcagtcagc aatcaattct cgccggatta gtggtggtcg ccattgcagg tatgatgggg
    18781 tcgctactcg ggtgtctatc cggtgtgctt ggcggacgcg cagacgcgat tatcatgcgc
    18841 atcatggaca ttatgctgtc gattccttcg ctggtactga caatggcact ggcagccgct
    18901 ctcgggccga gtttgtttaa cgccatgctg gcgattgcta ttgtgcgaat tcccttttat
    18961 gtgcgcctgg cgcgggggca aacattagtt gttcgccagt atacctatgt tcaggcggcg
    19021 aaaacctttg gtgcgtcgcg ttggcatctg atcaactggc atattttacg taactccctg
    19081 ccgccgctga ttgtgcaggc atcgctggat atcggtagcg cgattttaat ggccgccacg
    19141 ttgggattta ttggccttgg tgctcaacaa ccgagtgctg aatggggggc gatggtggcg
    19201 aatggtcgca actatgtgct cgatcaatgg tggtattgcg catttccggg ggcagcgatt
    19261 ttgcttaccg ccgtcgggtt taatctcttt ggcgatggta ttcgcgatct gcttgacccg
    19321 aaagcaggag gaaagcagtc atgacccaac ccgttctgga cattcaacaa ctgcatttga
    19381 gtttccccgg ttttaacggc gacgttcacg cgctcaacaa tgtgtcattg aaaatcaacc
    19441 gcggtgaaat tgtcggtctg gtgggagaat ccggctcggg taaatcagtc actgcaatgt
    19501 tgattatgcg tctgctaccg acgggcagtt attgcgtaca tcggggacat atttcactgc
    19561 tgggagaaga tgttcttaac gctcgggaaa agcagcttcg tcagtggcgc ggcgcacgag
    19621 tggcgatgat ctttcaggaa ccgatgaccg ccctcaatcc gacacgtcga ataggtcttc
    19681 agatgatgga cgtgatccgc catcatcaac caataagtcg tcgggaagcc agagctaaag
    19741 cgattgccct gctggaagag atgcaaatcc cggatgccgt ggaagttatg tcgcgctatc
    19801 cgtttgagct ttcaggtggt atgcgccagc gggtaatgat tgcgctggca ttctcctgcg
    19861 agccgcaatt gattattgcc gacgaaccga ctacggcgct ggacgtcacg gtacagttgc
    19921 aggtactgcg tctgcttaaa cataaagccc gcgccagtgg aactgcggta ctgttcatca
    19981 gccatgatat ggccgtggtg tcgcaactgt gcgatagcgt ttacgtgatg tatgccggaa
    20041 gcgtgattga aagcggcgtg acggcagacg ttatccatca tccccggcat ccgtatacca
    20101 ttggtttgct gcaatgcgca ccggaacatg gaataccgcg ccagccatta cccgccattc
    20161 cagggacggt accaaacctc acccatttgc ctgacggctg cgcttttcgc gatcgttgct
    20221 atgcggcagg tgcgcagtgt gaaaacgtcc cggcgctaac agcgtgtggt gacaacaacc
    20281 accgctgcgc ctgttggtat cctcagcagg aggtcattag tgtctgacac gttattaacg
    20341 ttacgcgacg tccatatcaa tttcccggcc cgaaaaaact ggcttggtaa aactacggaa
    20401 catgttcatg ccatcaatgg tattgattta cagatccgtc gtggtgaaac cttagggatc
    20461 gtcggtgagt caggttgcgg caaaagcacc ctcgcacagc ttttaatggg tatgctgcaa
    20521 ccgagccacg ggcagtacat ccgttcagga tcacaacgca ttatgcagat ggtgtttcag
    20581 gacccgctct cttcgcttaa tccgcgctta ccggtgtggc gcatcatcac ggaaccgctc
    20641 tggattgcta agcgtagtag tgaacaacag cggcgagcgt tggcagagga gctggctgtg
    20701 caggtgggta ttcgtccgga gtatctcgac cgcttgcccc atgcgttctc aggcgggcag
    20761 cggcaacgta tcgccattgc cagagcactc tcttcgcagc ctgacgtgat tgtgcttgat
    20821 gaaccaacct cggcgctgga tatctccgtg caggcgcaga tcctcaattt actggtaacg
    20881 ctacaggaaa atcgcgggct gacttatgtg ctgatttcac acaatgtctc ggtgatacgt
    20941 catatgagcg atcgggtggc ggtgatgtat ctcggacaga ttgtggaact aggagacgcg
    21001 caacaggtgc tgacagctcc ggcacatcca tacacccgat tattgctgga ttccctcccc
    21061 gccattgata aaccgctgga ggaagaatgg gcattacgta aaacggatct accaggaaac
    21121 cgcacgttgc cacaaggctg ttttttccgt gaacgttgcc ctctggcaac ccacgggtgt
    21181 aaagtccggc aatcattaac aataagggag gacggacgtg agatccggtg ctggcgggcg
    21241 ctgtagagac gctaacaacg catcaggcaa tcgcgcgcct gacgcgtcat ccggcaatgc
    21301 tttacgattt caactggtaa tccagcgtaa tttccgcttt cagtacctga gaaaccgggc
    21361 atcctgcttt tgctttctgg ataatgccgt caaaagtaga ggcatcaata cccggcaccg
    21421 caacttcgct cttcagtgcg attttagtaa tcgcaaaacc ggcatccact ttatccagcg
    21481 acacatcggc ggtggtatca atcgatgttg gcgtgaatcc cgcttccccc agcattaatg
    21541 aaagcgccat tgagaaacat gcggcatgcg ctgcgccaat cagttcttca gggttggttc
    21601 ctttttcgcc ttcaaaacgc gtgttaaatc catacggctg ttggttcagc acgccgctct
    21661 cggtggatac agttcccttc ccgcgtttga tatcgccttc ccagtgtgcc tgacctttct
    21721 tatggattgt cattgttgct ctcctgtggg cttaaaaagg aaattataga ctacgtgaga
    21781 aaccgcacga ggataagcag gttattccga ataaaatccg gcgaaaatat tacttctgca
    21841 cttaaattaa attcccacaa tagattaccg ggaatatata tatcaagaga tattgcatca
    21901 atatcattca actcaccaca ataataatac ctatcaatat catggggtta aaatataaaa
    21961 attatcaacc aggactaatc ttaacaacga agcggcaaat atttgccatg ctgaatgtgc
    22021 tttataaatc tgcgatccgt agcagacacc ataaatacac agacacggag aatcactatg
    22081 tttacttatt atcaggcaga aaattcaaca gcagaacccg ctctggttaa tgccattgag
    22141 caaggccttc gggcagagca cggtgttgtc actgaagatg acattctcat ggagctgacc
    22201 aaatgggtgg aagcttctga taacgacatc ctcagtgata tctaccagca aacgatcaat
    22261 tatgtggtca gtggccagca ccctacactt taaggtgcta tgcttgatcg gcaacctaat
    22321 ttaggggttt agcacgtgtt tcttcgctac ggcgatgttg tccttaaaac tagcaacagg
    22381 attgaggagt taaaatgaaa tcgaaccgtc aggcacgtca tattcttgga ctggaccata
    22441 aaatatctaa ccagcgcaaa atagttaccg aaggtgacaa atccagcgtg gtaaataacc
    22501 caaccggcag aaaacgcccc gctgaaaagt aattcataac catcagtcct caatgacgat
    22561 taaacaccat tgcctgcgca atggtgtttt tgtttttatc tgctttatac ttggggccga
    22621 cgccctggcg gtaaagcaaa gacgataaaa gcgtgccagg gatggatatt caaaaaagag
    22681 tgagtgacat ggaaccaaaa acaaaaaaac agcgttcgct ttatatccct tacgctggcc
    22741 ctgtattgct ggaatttccg ttgttgaata aaggcagcgc cttcagcatg gaagaacgcc
    22801 gtaacttcaa cctgctgggg ttactgccgg aagtggtcga aaccatcgaa gaacaagcgg
    22861 aacgagcatg gatccagtat cagggattca aaaccgaaat cgacaaacac atctacctgc
    22921 gtaacatcca ggacactaac gaaaccctct tctaccgtct ggtaaacaat catcttgatg
    22981 agatgatgcc agtcatttac accccaaccg tcggcgcagc ctgtgagcgt ttttctgaga
    23041 tctaccgccg ttcacgcggt gtgtttatct cttaccagaa ccgccacaat atggacgata
    23101 ttctgcaaaa cgtaccaaac cataatatca aagtgattgt ggtgactgac ggcgaacgta
    23161 ttctggggct tggtgaccag ggcatcggcg ggatgggcat tccgatcggt aaactgtcac
    23221 tctataccgc atgtggcggc atcagcccgg cgtataccct tccggtggtg ctggatgtcg
    23281 ggacgaacaa ccaacagctg cttaacgatc cgctgtatat gggctggcgt aatccgcgta
    23341 tcactgacga cgaatactat gaattcgttg atgaatttat ccaggctgtg aaacaacgct
    23401 ggccggacgt actgttgcag tttgaagact tcgcacaaaa aaatgcgatg ccgttactta
    23461 accgctatcg caatgaaatt tgttctttta acgatgacat tcagggcacc gcggcggtaa
    23521 cggtcggcac actgatcgca gccagccgcg cggcgggtgg tcaactgagc gagaaaaaga
    23581 ttgtcttcct cggcgcaggc tctgcggggt gcgggattgc cgaaatgatc atcgcccaga
    23641 cccagcgcga aggattaagc gaggaagcgg cgcggcagaa agtctttatg gtcgatcgct
    23701 ttggcctgct gaccgacaag atgccgaacc tgctgccttt ccagaccaaa ctggtgcaga
    23761 aacgcgaaaa cctcagcgac tgggataccg acagcgatgt gctgtcactg ctggatgtgg
    23821 tgcgcaatgt aaaaccagat attctgattg gcgtctcagg acagaccggg ctgtttacgg
    23881 aagagatcat ccgtgagatg cacaaacact gtccgcgtcc gatcgtgatg ccgctgtcta
    23941 acccgacttc acgcgtcgaa gcaacaccgc aggacattat cgcctggact gaaggaaacg
    24001 cgctggtcgc cactggcagt ccatttaatc cagtggtatg gaaagataaa atctacccta
    24061 tcgcccagtg taataacgcc tttattttcc cgggcatcgg gctgggtgtt attgcttccg
    24121 gcgcgtcacg tatcaccgat gaaatgctga tgtcggcaag tgaaacgctt gctcagtatt
    24181 cgccgctggt cctgaacggc gaaggtctgg tactaccgga actgaaagat atacagaaag
    24241 tctcccgcgc aattgcgttt gcggttggca aaatggcgca gcagcaaggc gtggcggtga
    24301 aaacctccgc cgaagctctg caacaggcca ttgatgataa tttctggcaa gccgaatacc
    24361 gcgactaccg ccgtacctcc atctaagcct gcgcccggta gtgaaggcta ccgggcaatt
    24421 tccctctccc tttttcagat ctcatccata ctgggtagtg gcgaataaat ctcatttgcc
    24481 tcacctgcta tgcagaacat catccgaaaa ggaggaacta tgaaggctgc agttgttacg
    24541 aaggatcatc atgttgacgt tacggataaa acactgcgct cactgaaaca tggcgaagcc
    24601 ctgctgaaaa tggagtgttg tggtgtatgt cataccgatc ttcatgttaa gaatggcgat
    24661 tttggtgaca aaaccggcgt gattctggga cacgaaggta ttggtgtggt ggcagaagtt
    24721 ggcccaggtg tcacttcatt aaaaccaggc gatcgtgcca gcgtggcgtg gttctatgaa
    24781 ggatgcggtc attgcgaata ctgtaacagt ggtaacgaaa cgctctgccg ttcagtaaaa
    24841 aatgccggat acagcgttga tggcgggatg gcggaagagt gcatcgtggt cgccgattac
    24901 gcggtaaaag tgccagatgg cctggactcg gcggcggcca gcagcattac ctgtgcgggg
    24961 gtcaccacct acaaagccgt taagctgtca aaaattcgtc cagggcagtg gattgctatc
    25021 tacggtcttg gcggtctggg taacctcgcc ctgcaatacg cgaagaatgt ctttaacgcc
    25081 aaagtgatcg ccattgatgt caatgatgag cagttaaaac tggcaaccga aatgggcgct
    25141 gatttagcga ttaactcacg caccgaagac gccgccaaaa ttgtgcagga aaaaaccggt
    25201 ggcgctcacg ctgcggtggt gacagcggta gctaaagctg cgtttaactc ggcagttgat
    25261 gctgtccgtg caggcgggcg tgttgtggca gtcggtctgc cgccggagtc tatgagcctg
    25321 gatatcccac gccttgtgct ggatggtatt gaagtggtcg gttcgctggt cggcacgcgc
    25381 caggatttaa ctgaagcctt ccagtttgcc gccgaaggca aagtggtacc gaaggtcgcc
    25441 ctgcgtccgt taacggacat caacacaatc tttactgaga tggaagaagg caaaatccgt
    25501 ggccgtatgg cgattgattt ccgccgctaa gaggcctttg ctgcgactgc catgttcggg
    25561 tcgcagcatc gcacactctc caacatgaaa tggctaaatg gattattgtt gcgtaggaag
    25621 gaacaataat gatagtgttc ctggtgaagg aacgctactg agagtaaaga cactgatgaa
    25681 aatggccaat catccccgcc caggagacat tattcaggaa tcactggacg aacttaatgt
    25741 cagcctgcgc gagtttgcca gagcaatgga aattgctccc tcaacggcaa gccgattgct
    25801 gaccggaaaa gcagctttga cgccagaaat ggcaattaaa ctttccgtgg tgatcggcag
    25861 ttcgccgcaa atgtggctga atctgcaaaa cgcctggagc ctggcagagg ctgaaaaaac
    25921 ggtggatgtg tcgcgactgc gccgtctggt tacgcaataa aaaaatggcg cttcttaaag
    25981 cgccattttc agcttaaagt tcaaaagaga ttatatccct tcttcactct cttttttcgc
    26041 ttctgccttc tcgatttcac gataccagcg cggatggtgt ttcttcgccc agcgacggct
    26101 caccttccct tcgatcatcc ctttaatcga tcctttcacc cagaatgcca tatacatatg
    26161 gatcaggatg gcgtggatca ggatgatacc cgcagccgcg tgaatcagca ggctgtagcg
    26221 aacaacctgc atcgggaagt actgcgcaaa gtacggacgc cagataatca ccccggtcac
    26281 cagcagcacg aaaatcatgc tcatgatcga ccagaacatc atcttctgcc cggcgttgta
    26341 cttaccaaca tccgccactt tgtgctcatt gccttttaat acttcgacaa tgttcaacag
    26401 ccacggaata tctttcttat ccgggatgtt gtgatgcaca aaacgcacaa acataaacat
    26461 cagcgcgacg aaaatcgcaa tgccgaagaa cgggtgcaaa atgcgtccca tctgcggcgt
    26521 accgaaggtt tgcgtcagcc attgcagcgt cgggaagaag aacgaaatcc cggacagcgc
    26581 caccaggaag aagcaaatca ccacggtcca gtgacaggcg cgatcaataa acttggtgcg
    26641 cacaatcatt ttcgacttac tcatgatgct cctcctcgtc atcgtccact tccttattcg
    26701 ggccaatacc gatgtagtgg aaaatcaacc cggcaaaagt ggcgataaag ccagccgctg
    26761 ccagcggttt caacgcgcct ttccacaagt tcaccgatgt gtcgatcttc ggatctttcg
    26821 gcagaccgtg atacagctcc ggctgatcgg cgtgatgcaa cacgtacatg acgtgcgtac
    26881 caccgacccc ttccgggttg tagacgccag catgttcgta accacgcgct ttcagtttcg
    26941 ccacgcgctg ttccgccagc tccagcatct ccttcttggt gccgaagtgg atagccccgg
    27001 tcggacaggt tttcacacaa gctggttcct ggccgacgct gacgcgatcg acgcagagcg
    27061 tgcatttata tacccggtta tcctctttgt tgaggcgcgg aatattaaac ggacacccgg
    27121 caatgcagta accacagccg atgcagtttt ccgactggaa atcgacaatc ccgttagcgt
    27181 actgaatgat tgcaccagca gacgggcacg ccttcaggca gcccggatct tcacagtgca
    27241 tacagccgtc tttacggatc agccactcca gcttgccgtt ctgttcggtt tcgctaaagc
    27301 gcatcacagt ccaggacttg gcgctcagat cggcggggtt atcgtaaacc ccgacgcagt
    27361 gccccacttc atcacggatg tcgttccact ccgaacacgc cacctgacag gctttacagc
    27421 cgatacaggt ggaaacgtcg ataagttttg cgacttctgc tttgtaatca cgcacctgcg
    27481 aaggcggcgt gatggagtta gttgcggacc ttttgataat gtcctgcgtt tccatagcca
    27541 tctgttcgcc cccttacgcc ttctcgatgt tgactaagaa cgctttatat tccggcgttt
    27601 gcgagtttgc atcaccgaca ttcggcgtca gagtgttagc gatataacct ttacgcgcga
    27661 caccctcaaa gccccagtgg attggaatac ccaccgtttc aacctgctga ccgtttacat
    27721 tcagcggttt cagacggcgc gttaccaccg ccaccgcgcg gataaagcca cgcttgcttg
    27781 agacagtgac acgatcgcca ttattaatgc ctttcgccgc cgccagcgtt tcgctgattt
    27841 ccacaaactg ttccggctga gcaattgcgt tgagcaacgc gtgcttggtc catgtgtgga
    27901 agtgctcggt cagacgatag gtcgtaccca catacgggaa ctgctctttt ttacccatcc
    27961 gcagcgcgtc ttgttcatac agacgaacga ccgggttaga caccacgttc ggatgcagcg
    28021 ggttagtgcc cagcggcgtt tcgattggct cgtagtgttc cgggaacgga ccttccgcca
    28081 ttttgttgat ggcaaacagg cgtcccatcc cttccggctg catgataaac ggtccggttg
    28141 gtgtacctgg cgcggcattg ccgaagtccg gaatatcgtt acccgtccac ttgctgccgt
    28201 tccactggat cagcatccgt ttcggatccc acggtttacc gttgatatcc gccgaagcac
    28261 ggttgtagag tacgcgacgg ttgagcggcc acgcccaggc ccatcccagc gtattcccca
    28321 gaccagatgg gtcggagtta tcgcggttag ccatctggtt gccctgctct gtccagctac
    28381 cggtgtagat ccagcaagac gatgcggttg taccgtcatc acgcagatgc gcaaagctac
    28441 tcagcaactg acctttcttc gcaatcagca cgccattggc atcatagaga tcttccagcg
    28501 cgtagccgtt gttctcttta gctacttcgt cagattgcgg ttcgtgcggc tgcttgtagt
    28561 tccagctcat cttcatcagc ggttctacgc ctttaccacc ttcggcctgg tacaactcgc
    28621 gcagatgatg gtagataccc gccagaattt cgccgtcgtt acgcgcttcg cccggcgcgt
    28681 cctgaccttt ccagtgccac tgcaaccagc gaccggagtt agcgatagaa ccatcttctt
    28741 cagcaaagca ggtcgaaggc agacggaata cttcagtctg aatagacgcc ggatcgacat
    28801 cgttcgactc gccgtggttc tgccagaagg tagaagtttc agtcaccagc ggatcgatta
    28861 ccaccatgta cttcagcttg ctcaggcagc tcaccacttt gtttttgtcc gggaaggacg
    28921 caaccgggtt aaagccctgg cagaaataac cggtgacttt gccttcgtcc atcatgttga
    28981 aatactttat gacgtcgtag gtctggtccc acttcggcag ccagtcgtag ccccagttgt
    29041 tctctttttg cgcggcatcg ccgtagaaag atttcatcag gctaacgaag aacttcggat
    29101 agttgctcca gtagttcacc tgatcagcca gcgtcgcttt cggcgtattc gcttccagat
    29161 acgactgcaa atcaacctgt ttttctgacg gcagcgtcag ataacccggc aggctggttg
    29221 agagcagacc taagtcggtc aggccctgaa tgttggagtg accacgcaat gcgttcacgc
    29281 cgccaccggc catacccatg ttaccgagca gcagctggat catcgccata gtacggatgt
    29341 tctgcgcacc cacggtgtgc tgcgtccagc ccagcgcgta caggaaggtg gttgtgcgat
    29401 ccggtgcgct ggtggaggcc agcacttcac acactttcag gaagtcggct tttggcgtac
    29461 cgcagatgtt ttctactacg tccggcgtgt agcgggaaac gtgcgctttc agcaagttcc
    29521 acacacagcg cggatgagtc agtgtttcat cgcgtttcgc atagccgttt tcatcgaact
    29581 gatagttcca ggacgattta tcgtactggc gtttttcagc gtcataaccg ctgaacaggc
    29641 catcttcgaa agcaaaatca tcacgcacca gcaggctggc gttggtgtaa tgcttaacgt
    29701 attcggcgtt gattttgttg ttttcgatca ggtagcgcaa aacgccagac aggaacgtaa
    29761 tgtccgtacc ggaacgaata ggtgcgtaaa tatccgccac agaagcggta cgcgtaaaac
    29821 ggggatcgac aacgatcaag gttgcatcgt tgttgttttt cgcttccatc gcccagcgga
    29881 aaccgacggg atgtgcttca gcagcgttac cacccatcac cattacgacg ttagcgtttt
    29941 tgatatccac ccagtggttg gtcatcgcac cgcgaccaaa tgttggagca agacttgcta
    30001 ccgttggtcc gtgtcagacg cgcgcctggt tgtctaccgc cagcatcccg agggagcggg
    30061 caaatttttg agtcagcatc ccggtttcgt tgctggcacc ggaggcacac agcataccgg
    30121 tagaaagcca acggtttacc gttacgccct gctcgttctt ttcaataaag ttagcgtcac
    30181 ggtcagcttt catcagcttc gcaatacggg agaatgcttc atcccagcta atgcgctgcc
    30241 atttatcaga acctggcgca cgatattccg ggtagcgcag acggttttcg ctgttgacgt
    30301 aatccagcaa accggcccct ttcgggcaca gcgcaccacg gcttaccgga tgatccgggt
    30361 caccttcaat gtgataaatc gcttctctgg cgtttttcgc gccatcaccc aggctataca
    30421 tcaatagccc gcaacctacg gaacagtatg tgcaggtgtt acggatctct ttagcgcgta
    30481 ataatttgta gtttcgcgcc tgagccagtg cttgctttgg ggcaaagccc aatgccgcta
    30541 ctgttgttcc agccataccg cccgcgcaga ttttaaaaaa ttgtctgcga ctgacgtcca
    30601 ttgctttcct cttttttcag gggtattact gcgcgaggaa actaacagta aaattctgaa
    30661 tctttttgcg cgaaatcaaa aagaacacgt gtttgccaca aaataatccg cctgcgcaaa
    30721 ttgacctacc tcaatagcgg tagaaaaacg caccactgcc tgacaggcca gttaaaaaaa
    30781 tgctataaaa ttcagcttaa tttttaacgg caagagagac aaaacagcga gcatgacacg
    30841 acaaaaagca acgctcatag ggctaatagc gatcgtcctg tggagcacga tggtaggatt
    30901 gattcgcggt gtcagtgagg ggctcggccc ggtcggcggc gcagctgcta tctattcatt
    30961 aagcgggctg ctgttaatct tcacggttgg atttccgcgt attcggcaga tcccgaaagg
    31021 ctatttactc gccgggtgtc tgttattcgt cagctatgaa atctgtctgg cgctttcctt
    31081 aggatatgcg gcgacccgtc atcaggcgat tgaagtgggt atggtgaact atctgtggcc
    31141 cagcctgaca attctctttg ccattctgtt taatggtcag aaaaccaact ggctgattgt
    31201 accaggatta ttattagccc tggttggcgt ctgctgggtg ttaggtggtg acaatgggtt
    31261 acattatgat gaaatcatca ataatatcac caccagccca ttgagttatt tcctggcgtt
    31321 tattggtgcg tttatctggg cagcctattg cacagtaacg aataaatatg cacgcggatt
    31381 taacggaatt accgtttttg tcctgctaac gggagcaagt ctgtgggttt actattttct
    31441 cacgccacaa ccagaaatgg tatttagcac gccagtcatg attaaactca tctctgcggc
    31501 atttacctta ggatttgctt atgctgcatg gaacgtcggt atattacatg gcaacgtcac
    31561 cattatggcg gtaggttcgt attttacgcc cgtcctttcc tcagcgcttg cagccgtgct
    31621 gctcagcgcc ccgctgtcgt tctcgttctg gcaaggcgcg ctaatggtct gcggcggttc
    31681 cctgctctgc tggctggcga cacgtcgtgg ctaaaataat tgtcgggtct acggcccggc
    31741 agttaatcag ataaattccg acaatataaa aaataaattt caaataccag tagttcac
//
LOCUS       DADXDL010000058        31625 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.058, whole genome shotgun sequence.
ACCESSION   DADXDL010000058 DADXDL010000000
VERSION     DADXDL010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 31625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31625
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.058"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..117
                     /locus_tag="IRB70_002951"
     CDS             <1..117
                     /locus_tag="IRB70_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HBC0632839.1"
                     /translation="QGEGKDLNNESTPMAFENIKQVIDDMATDATMFDVNKK"
     gene            complement(152..1363)
                     /gene="ydcO"
                     /locus_tag="IRB70_002952"
     CDS             complement(152..1363)
                     /gene="ydcO"
                     /locus_tag="IRB70_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001748359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BenE family transporter YdcO"
                     /protein_id="HBC0632840.1"
                     /translation="MLRCLYAITHEVTMRLFSIPPPTLLAGFLAVLIGYASSAAIIWQ
                     AAIVAGATTAQISGWMTALGLAMGVSTLALTLWYRVPVLTAWSTPGAALLVTGLQGLT
                     LNETIGVFIVTNALIVLCGITGLFARLMRIIPHSLAAAMLAGILLRFGLQAFASLDGQ
                     FTLCGSMLLVWLATRAVAPRYAVIAAMIIGGVIVIAQGDVVTTDVVFKPVLPTYISPD
                     FSFAHSLSVALPLFLVTMASQNAPGIAAMKAAGYSAPVSPLIVFTGLLALVFSPFGVY
                     SVGIAAITAAICQSPEAHPDKDQRWLAAAVAGIFYLLAGLFGSAITGMMAALPVSWIQ
                     MLAGLALLSTIGGSLYQALHNERERDAAVVAFLVTASGLTLAGIGSAFWGLIAGGVCY
                     VVLNLIADRNR"
     gene            1416..1952
                     /gene="sutR"
                     /locus_tag="IRB70_002953"
     CDS             1416..1952
                     /gene="sutR"
                     /locus_tag="IRB70_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator SutR"
                     /protein_id="HBC0632841.1"
                     /translation="MENLARFLSTTLKQLRQQRGWSLSRLAEATGVSKAMLGQIERNE
                     SSPTVATLWKIATGLNVPFSTFISPPQSATPSVYDPQQQAMVITSLFPYDPQLCFEHF
                     SIQMAPGAISESTPHEKGVIEHVVVIDGQLDLCVDGEWQSLNCGEGARFAADVTHVYC
                     NGGEQIVHFHSLIHYPRS"
     gene            2025..3986
                     /gene="rlhA"
                     /locus_tag="IRB70_002954"
     CDS             2025..3986
                     /gene="rlhA"
                     /locus_tag="IRB70_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA 5-hydroxycytidine C2501 synthase"
                     /protein_id="HBC0632842.1"
                     /translation="MTVSSHRLELLSPARDAAIAREAILHGADAVYIGGPGFGARHNA
                     SNSLKDIAELVPFAHRYGAKIFVTLNTILHDDELEPAQRLITDLYQTGVDALIVQDMG
                     ILELDIPPIELHASTQCDIRTVEKAKFLSDVGFTQIVLARELNLEQIRAIHQATDATI
                     EFFIHGALCVAYSGQCYISHAQTGRSANRGDCSQACRLPYTLKDDQGRVVSYEKHLLS
                     MKDNDQTANLGALIDAGVRSFKIEGRYKDMSYVKNITAHYRQMLDAIIEERGDLTRAS
                     SGRTEHFFVPSTEKTFHRGSTDYFVNARKGDIGAFDSPKFIGLPVGEVLKVAKDHIDV
                     AVTEPLANGDGLNVMIKREVVGFRANTVEKTGENQYRVWPNEMPADLHKIRPHHPLNR
                     NLDHNWQQALTKTSSERRVAVDIELGGWQEQLILTLTSEEGVSITHTLDGQFDEANNA
                     EKAMNNLKDGLAKLGQTIYYARDVQINLPGALFVPNSLLNQFRREAADMLDAARLAGY
                     QRGSRKPVADPAPVYPQTHLSFLANVYNQKAREFYHRYGVQLIDAAYEAHEEKGEVPV
                     MITKHCLRFAFNLCPKQAKGNIKSWKATPMQLVNGDEVLTLKFDCRPCEMHVIGKIKN
                     HILKMPLPGSVVASVSPDDLLKTLPKRKG"
     gene            complement(4078..4308)
                     /locus_tag="IRB70_002955"
     CDS             complement(4078..4308)
                     /locus_tag="IRB70_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2554 family protein"
                     /protein_id="HBC0632843.1"
                     /translation="MFSKALSVVLLTCALFSGQLMAGHKGHEFMWVKNVDHQLRHEAD
                     SDELRAVAEESAEGLREHFYWQKSRKPEAGQR"
     gene            4530..4706
                     /gene="hicA"
                     /locus_tag="IRB70_002956"
     CDS             4530..4706
                     /gene="hicA"
                     /locus_tag="IRB70_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415954.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin HicA"
                     /protein_id="HBC0632844.1"
                     /translation="MKQSEFRRWLESQGVDVANGSNHLKLRFHGRRSVMPRHPCDEIK
                     EPLRKAILKQLGLS"
     gene            4752..5168
                     /gene="hicB"
                     /locus_tag="IRB70_002957"
     CDS             4752..5168
                     /gene="hicB"
                     /locus_tag="IRB70_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415955.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin HicB"
                     /protein_id="HBC0632845.1"
                     /translation="MRYPVTLTPAPEGGYMVSFVDIPEALTQGETVAEAMEAAKDALL
                     TAFDFYFEDNELIPLPSPLNSHDHFIEVPLSVASKVLLLNAFLQSEITQQELARRIGK
                     PKQEITRLFNLHHATKIDAVQLAAKALGKELSLVMV"
     gene            5247..6653
                     /locus_tag="IRB70_002958"
     CDS             5247..6653
                     /locus_tag="IRB70_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBC0632846.1"
                     /translation="MKKYQQLAEQLREQIASGIWQPGDRLPSLRDQVALSGMSFMTVS
                     HAYQLLESQGYIIARPQSGYYVAPQAIKMPKAPVIPVTRDEAVDINTYIFDMLQASRD
                     PSVVPFASAFPDPRLFPLQQLNRSLAQVSKTATAMSVIENLPPGNAELRQAIARRYAL
                     QGITISPDEIVITAGALEALNLSLQAVTEPGDWVIVENPCFYGALQALERLRLKALSV
                     ATDVKEGIDLQALELALQEYPVKACWLMTNSQNPLGFTLTPQKKAQLVALLNQYNVTL
                     IEDDVYSELYFGREKPLPAKAWDRHDGVLHCSSFSKCLVPGFRIGWVAAGKHARKIQR
                     LQLMSTLSTSSPMQLALVDYLSTRRYDAHLRRLRRQLAERKQRAWQALLRYLPAEVKI
                     HHNDSGYFLWLELPAPLDAGELSLAALTHHISIAPGKMFSTGENWSRFFRFNTAWQWG
                     EREEQAVKQLGTLIQERL"
     gene            6898..8043
                     /locus_tag="IRB70_002959"
     CDS             6898..8043
                     /locus_tag="IRB70_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBC0632847.1"
                     /translation="MSKTFARSSLCALTMTLMTAHAAEPPTNLDKPEGRLDIIAWPGY
                     IERGQTDKQYDWVTQFEKETGCAVNVKTAATSDEMVSLMTKGGYDLVTASGDASLRLI
                     MGKRVQPINTALIPNWKALDPRVVKGDWFNVGGKVYGTPYQWGPNLLMYNTKTFPTPP
                     NSWQVVFVEQNLPDGKSNKGRVQAYDGPIYIADAALFVKATQPQLGISDPYQLTEEQY
                     QAVLKVLRDQHSLIHRYWHDTTVQMSDFKNEGVVASSAWPYQANALKAEGQPVATVFP
                     KEGVTGWADTTMLHSEAKHPVCAYKWMNWSLTPKVQGDVAAWFGSLPVVPQGCKASPL
                     LGEKGCETNGFNYFDKIAFWKTPIAEGGKFVPYSRWTQDYIAIMGGR"
     gene            8061..9074
                     /locus_tag="IRB70_002960"
     CDS             8061..9074
                     /locus_tag="IRB70_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0632848.1"
                     /translation="MTYAVEFDNVSRLYGDVRAVDGVSIAIKDGEFFSMLGPSGSGKT
                     TCLRLIAGFEQLSGGAISIFGKPASNLPPWERDVNTVFQDYALFPHMSILDNVAYGLM
                     VKGVDKKQRHAMAQEALEKVALGFVQQRKPSQLSGGQRQRVAIARALVNEPRVLLLDE
                     PLGALDLKLREQMQLELKKLQQSLGITFIFVTHDQGEALSMSDRVAVFNNGRIEQVDS
                     PRDLYMRPRTPFVAGFVGTSNVFDALMADKLCGMTGSFALRPEHIRFNIPGEVQANGT
                     IQAVQYQGAATRFELRLNGGEKLLVSQANMTGEELPATLTPGKQVMVSWSRDVMVPLV
                     EER"
     gene            9075..10016
                     /locus_tag="IRB70_002961"
     CDS             9075..10016
                     /locus_tag="IRB70_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0632849.1"
                     /translation="MAMNVLQSPSHPGLGKVSGFFWRNPGLGLFLLLLGPLMWFGIVY
                     FGSLLTLLWQGFYTFDDFTMSVTPELTLANIRALFNPANYDIILRTLIMAVAVTIASA
                     ILAFPMAWYMARYTSGKMKAFFYIAVMLPMWASYIVKAYAWTLLLAKDGVAQWFLQHL
                     GLEPLLTAFLTLPAVGGNTLSTSGLGRFLVFLYIWLPFMILPVQAALERLPPSLLQAS
                     ADLGARPRQTFRYVVLPLAIPGIAAGSIFTFSLTLGDFIVPQLVGPPGYFIGNMVYSQ
                     QGAIGNMPMAAAFTLVPIVLIALYLAFVKRLGAFDAL"
     gene            10006..10800
                     /locus_tag="IRB70_002962"
     CDS             10006..10800
                     /locus_tag="IRB70_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0632850.1"
                     /translation="MHSERAPFFLKLAAWGGVVFLHFPILIIAAYAFNTEDAAFSFPP
                     QGLTLRWFSVAAQRSDILDAVTLSLKVAALATLIALVLGTLAAAALWRRDFFGKNAIS
                     LLLLLPIALPGIVTGLALLTAFKTINLEPGFFTIVVGHATFCVVVVFNNVIARFRRTS
                     WSLVEASMDLGANGWQTFRYVVLPNLSSALLAGGMLAFALSFDEIIVTTFTAGHERTL
                     PLWLLNQLGRPRDVPVTNVVALLVMLVTTLPILGAWWLTREGDNGQ"
     gene            10822..12246
                     /gene="patD"
                     /locus_tag="IRB70_002963"
     CDS             10822..12246
                     /gene="patD"
                     /locus_tag="IRB70_002963"
                     /EC_number="1.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminobutyraldehyde dehydrogenase"
                     /protein_id="HBC0632851.1"
                     /translation="MQHKLLINGELVSGEGEKQPVYNPATGDVLLEIAEASAEQVDAA
                     VRAADAAFAEWGQTTPKARAECLLKLADVIEENGQVFAELESRNCGKPLHSAFNDEIP
                     AIVDVFRFFAGAARCLNGLAAGEYLEGHTSMIRRDPLGVVASIAPWNYPLMMAAWKLA
                     PALAAGNCVVLKPSEITPLTALKLAELAKDIFPAGVINVLFGRGKTVGDPLTGHPKVR
                     MVSLTGSIATGEHIISHTAPSIKRTHMELGGKAPVIVFDDADIEAVVEGVRTFGYYNA
                     GQDCTAACRLYAQKGIYDTLVEKLGAAVATLKSGSPDDESTELGPLSSLAHLERVSKA
                     VEEAKATGHIKVITGGEKRKGNGYYYAPTLLAGALQDDAIVQKEVFGPVVSVTLFDNE
                     EQVVNWANDSQYGLASSVWTKDVGRAHRVSARLQYGCTWVNTHFMLVSEMPHGGQKLS
                     GYGKDMSLYGLEDYTVVRHVMVKH"
     gene            complement(12343..12438)
                     /gene="yncL"
                     /locus_tag="IRB70_002964"
     CDS             complement(12343..12438)
                     /gene="yncL"
                     /locus_tag="IRB70_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response membrane protein YncL"
                     /protein_id="HBC0632852.1"
                     /translation="MNVSSRTVVLINVFAAVGLFTLISMRFGWFI"
     gene            12633..12806
                     /gene="ortT"
                     /locus_tag="IRB70_002965"
     CDS             12633..12806
                     /gene="ortT"
                     /locus_tag="IRB70_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415962.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orphan toxin OrtT"
                     /protein_id="HBC0632853.1"
                     /translation="MSLYQHMLVFYAVMAAIAFLITWFLSHDKKRIRFLSAFLVGATW
                     PMSFPVALLFSLF"
     gene            12892..13125
                     /locus_tag="IRB70_002966"
     CDS             12892..13125
                     /locus_tag="IRB70_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcY family protein"
                     /protein_id="HBC0632854.1"
                     /translation="MSHLDEVIARVDAAIEESVIAHMNELLIALSDDAELSREDRYTQ
                     QQRLRTAIAHHGRKHKEDMEARHEQLTKGGTIL"
     gene            complement(13126..13575)
                     /locus_tag="IRB70_002967"
     CDS             complement(13126..13575)
                     /locus_tag="IRB70_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DMT family transporter"
                     /protein_id="HBC0632855.1"
                     /translation="MNQSLTLAFLIAAGIGLVVQNTLMVRITQTSSTILIAMLLNSLV
                     GIVLFVSILWFKQGMAGFGELVSSVRWWTLIPGLLGSFFVFASISGYQNVGAATTIAV
                     LVASQLIGGLVLDIFRSHGVPLRALFGPICGAILLVVGAWLVARRSF"
     gene            complement(13572..14090)
                     /gene="mddA"
                     /locus_tag="IRB70_002968"
     CDS             complement(13572..14090)
                     /gene="mddA"
                     /locus_tag="IRB70_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-methionine sulfoximine/L-methionine sulfone
                     acetyltransferase"
                     /protein_id="HBC0632856.1"
                     /translation="MSIRFARKADCAAIAEIYNHAVLYTAAIWNDQTVDADNRIAWFE
                     ARTLAGYPVLVSEQDGVVTGYASFGDWRSFDGFRHTVEHSVYVHPDHQGKGLGRKLLS
                     RLIDEARDCGKHVMVAGIESQNQASLHLHQSLGFVITAQMPQVGTKFGRWLDLTFMQL
                     QLDERTEPDAIG"
     gene            14271..15308
                     /gene="curA"
                     /locus_tag="IRB70_002969"
     CDS             14271..15308
                     /gene="curA"
                     /locus_tag="IRB70_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415966.6"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent curcumin/dihydrocurcumin
                     reductase"
                     /protein_id="HBC0632857.1"
                     /translation="MGQQKQRNRRWVLASRPHGAPVPENFRLEEDDVATPGEGQVLLR
                     TVYLSLDPYMRGRMSDEPSYSPPVDIGGVMVGGTVSRVVESNHPDYQPGDWVLGYSGW
                     QDYDISSGDELVKLGDHPQNPSWSLGVLGMPGFTAYMGLLDIGQPKEGETLVVAAATG
                     PVGATVGQIGKLKGCRVVGVAGGAEKCRHATEVLGFDVCLDHHADDFAEQLAKACPKG
                     IDIYYENVGGKVFDAVLPLLNTSARIPVCGLVSSYNDTELPPGPDRLPLLMATVLKKR
                     IRLQGFIISQDYGHRIHEFQQEMGQWVKEGKIHYREQVTNGLENAPQTFIGLLNGKNF
                     GKVVIRVAGDD"
     gene            15507..16172
                     /gene="mcbR"
                     /locus_tag="IRB70_002970"
     CDS             15507..16172
                     /gene="mcbR"
                     /locus_tag="IRB70_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310081.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid/biofilm transcriptional regulator
                     McbR"
                     /protein_id="HBC0632858.1"
                     /translation="MPGTEKIPHISLTMQVENDLKHQLSIGALKPGARLITKNLAEQL
                     GMSITPVREALLRLVSVNALSVAPAQAFTVPEVGKRQLDEINRIRYELELMAVTLAVE
                     NLTPQDLAELEELLEKLQQAQEKGDMEQIINANRLFRLAIYHRSNMPILCEMIEQLWI
                     RMGPGLHYLYEAINPAELRERIESYHELLAALKVKDKEGCSHCLAEIMQKNVAMLYQQ
                     YNR"
     gene            complement(16208..18310)
                     /locus_tag="IRB70_002971"
     CDS             complement(16208..18310)
                     /locus_tag="IRB70_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent receptor"
                     /protein_id="HBC0632859.1"
                     /translation="MKIFSVRQTVLPALLVLSPVVFAADEQTMIVSAAPQVISELDTP
                     AAVSVVDGEEMRLATPRINLSESLTGVPGLQVQNRQNYAQDLQLSIRGFGSRSTYGIR
                     GIRLYVDGIPATMPDGQGQTSNIDLSSVQNVEVLRGPFSALYGNASGGVMNVITQTGQ
                     QPPTIEASSYYGSFGSWRYGLKATGATGDGTQPGDVDYTVSTTRFTTHGYRDHSGAQK
                     NLANAKLGVRIDDASKLSLIFNSVDIKADDPGGLTEAEWKANPQQAPRAEQYDTRKTI
                     KQTQAGLRYERSLSSRDEMSVMMYAGERETTQYQSIPMAPQLNPSHAGGVITLQRHYQ
                     GIDSRWTHRGELGVPLTFTTGLNYENMSENRKGYNNFRLNSGVPEYGQKGELRRDERN
                     LMWNVDPYLQTQWQLSEKLSLDAGVRYSSVWFDSNDHYVTPGNGDDSGDASYHKWLPA
                     GSLKYAMTDAWNIYLAAGRGFETPTINELSYRADGQSGMNFGLKPSTNDTIEIGSKTR
                     IGDGLLSLALFQTDTDDEIVVDSSSGGRTTYKNAGKTRRQGAELAWDQRFAGDFRVKA
                     SWTWLDATYRSNVCNEQDCNGNRMPGIARNMGFASIGYIPEDGWYAGTEARYMGDIMA
                     DDENTAKAPSYTLVGLFTGYKYNYHNLTVDLFGRVDNLFDKEYVGSVIVNESNGRYYE
                     PAPGRNYGIGVNVAWRFE"
     gene            18552..19613
                     /locus_tag="IRB70_002972"
     CDS             18552..19613
                     /locus_tag="IRB70_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncE family protein"
                     /protein_id="HBC0632860.1"
                     /translation="MHLRHLFSSRLRGSLLLGSLLVASSFSTQAAEEMLRKAVGKGAY
                     EMAYSQQENALWLATSQSRKVDKGGVVYRLDPVTLEVTQAIHNDLKPFGATINNTTQT
                     LWFGNTVNSAVTAIDAKTGEVKGRLVLDDRKRTEEVRPLQPRELVADDATNTVYITGI
                     GKESVIWVVDGENIKLKTAIQNTGKMSTGLALDSKGKRLYTTNADGELITIDTADNKI
                     LSRKKLLDDDKEHFFINISLDTTNQRAFITDSKAAEVLVVDTRNGNILAKVAAPESLA
                     VLFNPARNEAYVTHRQAGKVSVIDAKSYKVVKTFDTPTHPNSLALSADGKTLYVSVKQ
                     KSTKQQEATQPDDVIRIAL"
     gene            complement(19726..21225)
                     /gene="ansP"
                     /locus_tag="IRB70_002973"
     CDS             complement(19726..21225)
                     /gene="ansP"
                     /locus_tag="IRB70_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310084.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-asparagine permease"
                     /protein_id="HBC0632861.1"
                     /translation="MSKHDTDTSDQHAAKRRWLNAHEEGYHKAMGNRQVQMIAIGGAI
                     GTGLFLGAGARLQMAGPALALVYLICGLFSFFILRALGELVLHRPSSGSFVSYAREFL
                     GEKAAYVAGWMYFINWAMTGIVDITAVALYMHYWGAFGGVPQWVFALAALTIVGTMNM
                     IGVKWFAEMEFWFALIKVLAIVTFLVVGTVFLGSGQPLDGNTTGFHLITDNGGFFPHG
                     LLPALVLIQGVVFAFASIEMVGTAAGECKDPQTMVPKAINSVIWRIGLFYVGSVVLLV
                     MLLPWSAYQAGQSPFVTFFSKLGVPYIGSIMNIVVLTAALSSLNSGLYCTGRILRSMA
                     MGGSAPSFMAKMSRQHVPYAGILATLVVYVVGVFLNYLVPSRVFEIVLNFASLGIIAS
                     WAFIIVCQMRLRKAIKEGKAADVSFKLPGAPFTSWLTLLFLLSVLVLMAFDYPNGTYT
                     IAALPIIGILLVIGWFGVRKRVAEIHSTAPVVEEDEEKQEIVFKPETAS"
     gene            21492..22109
                     /locus_tag="IRB70_002974"
     CDS             21492..22109
                     /locus_tag="IRB70_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase family protein"
                     /protein_id="HBC0632862.1"
                     /translation="MIKVYGVPGWGSTISELMLTLADIPYQFFDVSGFDHEGTSRELL
                     KTLNPLCQIPTLALENDEIMTETAAIALMVLDRRPDLAPPVGRAERQQFQRLLVWLVA
                     NVYPTFTFADYPERWAPDAPEQLKKNVIEYRKSLYIWLNSQLTAEPYAFGEQLTLVDC
                     YLCTMRTWGPGHEWFQDNATNISAIADAVCQLPKLQEVLKRNEII"
     gene            22185..22397
                     /locus_tag="IRB70_002975"
     CDS             22185..22397
                     /locus_tag="IRB70_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YncH family protein"
                     /protein_id="HBC0632863.1"
                     /translation="MLCFLIYITLPFIQLVYFISSEKKLTIHIVQMFQLLSQVFYNLK
                     MFLMMDMLGVGDAININTNKNIRQVC"
     gene            23220..25121
                     /locus_tag="IRB70_002976"
     CDS             23220..25121
                     /locus_tag="IRB70_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HBC0632864.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLNQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTIWQGDEVQRRVKGVVTWFELGENDKNQMLYSMKVHPPLWRA
                     GLRQNFRIFQNEDIKSILGTMLQENGVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAYKSTDQSLVLCDTVRHLPESFEIPWNPNTRTEVSTLCISQFRYSA
                     QIRPSSVVTKDYTFKRPGWAGRFEQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFARWQ
                     MDGWRNNAETARGMSRSPEIWPGRRIVLTGHPQANLNREWQVVASELHGEQPQAVPGR
                     QGAGTALENHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKF
                     NWDRYNPADQDSSCWIRVAQAWAGTGFGHLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HQENRTPGSLPGTKTQMTIRSKTYMGSGFNELKFDDATGREQVYIHAQKNMDTEVLND
                     RTTTVKHDHRETVKNDQTVTIQEGNRLLTVEKGHKITGVLKGSLSEDVFQDRGTIAGS
                     VHVDAVNNGGEGDGIQAYTAIKEILLAVEESKIALTPDGIQLQVGESTVIRLSKDGIT
                     IVGGSVFIN"
     gene            25149..25610
                     /locus_tag="IRB70_002977"
     CDS             25149..25610
                     /locus_tag="IRB70_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DcrB-related protein"
                     /protein_id="HBC0632865.1"
                     /translation="MQFTFNEGHIQLPSQWQDQSMQVLVSTDNSGINLVITREAVPQG
                     TLTPELYQETLALYQGKLDGYTEHACREITLAEAPAWLLDYSWNGPEDEGNQGRISQI
                     AVFQRRGDTLLTFTFSTSLSLKNSQKTMLLEVIKSFTPLPPENDIQKDQPR"
     gene            25630..30483
                     /locus_tag="IRB70_002978"
     CDS             25630..30483
                     /locus_tag="IRB70_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001289041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PAAR domain-containing protein"
                     /protein_id="HBC0632866.1"
                     /translation="MSEGPGGPQGATAGGTLAMRMLSQQAMVASQMKRAANDKAIAQM
                     LASKKSGPPAARLGDEIQHKSFLGALAGAVLGAIVTIAEGCLIMAACATGPYALVLVP
                     ALMYASYKASDYVEEKQNQLESWINSFCDTDGAINTGSKNVNINGKPAARAAVTLPPP
                     PLTEAIPSPPQGEPSWGDIATDLLESAAEKAVPLAKAWGNAVITLTDSNAGIMDRVSA
                     GASLLFPAGPVLMEFATMVGGRGEIKKDVDFPEAGEDTALCDKENKPPRIAQGSSNVF
                     INNQPAARKGDKLECSAAIVEGSPDVFIGGEQVTYLDIQPEFPPWQRMILGGITIASY
                     LLPPAGLLGKLGNLAKLGKLGNLLGKSGKLLGAKLGALLGKTGKSLKSIANKVIRWVT
                     DPVDPVTGAYCDERTDFTLGQTLPLSFTRFHSSVLPLHGLTGVGWSDSWSEYAWVREQ
                     GNRVDIISQGTTLRFAFDGDSDTAVNPYHAQYILRRRDDYLELFDRDALSSRFFYDAF
                     PGMRLRHPVTDDTCDDRLAHSPADRMYMLGGMSDTASNRITFERDSQYRIMGVSHTDG
                     IRLKLTYHASGYLKAIHRTDNGIQMLATYEQDARGRLTEADARLDYHLFYEYDAADRI
                     IRWSDNDQTWSRFTYDAQGRCVTVTGAEGYYNATLDYGDGCTTVTDGKGIHRYYYDPD
                     GNILREAAPDGSTTMYEWDEFHHLLARHSPAGRVEKFEYNAAHGQLSRYTAADGAEWQ
                     YCYDERGLLSNITDPAGQTWTQQCDERGLPVSLVSPQGEETRLAYTPQGLLSGIFRQD
                     ERRLGIEYDHHNRPETLTDVMGREHHTEYSGHDLPVKMRGPGGQSVRLRWQQHHKLSG
                     LERTGTGAEGFRYDRHGNLLAWTDGNGVVWTMEYGPFDLPVARTDGEGHRWQYRYDKD
                     TLQLTEVINPQGESYRYILDNCGRVTEERDWGGVVWRYRYDADGLCTARVNGLEETIL
                     YSRDAAGRLAEVISPEGKTQYAYDKSGRLTGIFSPDGTSQRTGYDERGRVNVTTQGRR
                     AIEYHHPDEHTVIRCILPPEDERDRHPGESLLKTTYRYNAAGELTEVILPGDETLTFS
                     RDEAGREVLRHSNRGFACEQGWNAAGQLTSQRAGLFPAEATWGGLLPSLVREYRYDSA
                     GNMSAVTSREDYGRETRREYRLDRNGQVTAVTASGTGLGYGEGDESYGYDSCGYLKAQ
                     SAGRHRISVDTDMYQRGHRLKQTGNTDYSYDAAGRMVSRTRHRDGYRPETERFRWDSR
                     DQLTGYCSAQGEQWEYRHDASGRRTEKRCDRKKIRFTYLWDGDSIAEMREYRDDKLYS
                     VRHLVFNGFELLSQQFSRVRQPHPSVAPQWVTRTNHAVSDLTGRPLVLFNSEGKTVWR
                     PGQTSLWGLALSLPADTGYPDPRGELDPEADPGLLYAGQWQDAESGLCYNRFRYYEPE
                     TGMYLVSDPLGLLGGEQTYRYVPNPLGYVDPLGLAICPVMYDWYKYNRSQGMTAAQAH
                     QAIKNTSPQDVLNYALHRQGLSGHNYPIKFKEKFTVGNYKYEVRAHDVNPTAPAGSNS
                     ANGPIYRIGRSQSGTNPATNQGYGWEYGSPDGSWHHTSDLKTKSPNYNPGAANDTHIP
                     LPTGTIP"
     gene            30480..30869
                     /locus_tag="IRB70_002979"
     CDS             30480..30869
                     /locus_tag="IRB70_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000003345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632867.1"
                     /translation="MSEQNIINDIKHHNWKESWLDFSVFLYEHNRLIISGSDDLSYYH
                     TLEIIIDTPCYISGVMDWSCDLNEEFIKLSSCTDNAREMLVLEFYSEFELKFKVIAKK
                     ISINFDTVFYYKRENLKIGERLAYWIK"
     gene            30877..31528
                     /locus_tag="IRB70_002980"
                     /pseudo
     CDS             30877..31528
                     /locus_tag="IRB70_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001307661.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
BASE COUNT         8030 a         7883 c         8425 g         7287 t
ORIGIN      
        1 cagggcgaag gtaaagacct gaataacgaa agtacgccaa tggctttcga aaatattaaa
       61 caagttattg atgacatggc gaccgatgcc accatgtttg acgttaacaa aaagtagttc
      121 cagacgcgcc atcgttagat ggcgcttttt attatcggtt tctgtcagcg attaaattca
      181 acaccacgta acaaacgcct ccggcaatta atccccaaaa cgcagaacca atcccggcca
      241 gcgtcaatcc acttgccgtt accagaaatg ccaccaccgc cgcgtcgcgc tcacgctcat
      301 tatgcagcgc ctgatacaaa ctgccgccaa tggtactcaa cagcgccaga cctgccagca
      361 tctggatcca acttacgggc agggcagcca tcatcccggt aatggcacta ccaaacagac
      421 ctgcgagcaa atagaaaatg cctgcaacgg cagctgccag ccaacgttga tctttatccg
      481 gatgcgcttc cgggctttgg caaatagccg cggtgattgc cgcaataccg acggaataaa
      541 cgccgaaagg ggaaaaaacc agtgccagca atccagtaaa tacaattaat ggcgaaacag
      601 gagccgaata tccggctgct ttcattgctg cgatacccgg tgcgttttgc gatgccatcg
      661 tcaccagaaa aagggggagt gcaacgctca ggctgtgagc aaacgaaaaa tcagggctaa
      721 tataagtggg gagaacgggt ttaaagacaa catcagttgt gacaacgtca ccttgcgcga
      781 taacgatcac gcccccaata atcatcgcgg caattaccgc atagcgcggc gcaacggccc
      841 tggttgccag ccataccagc aacatactgc cacacaacgt aaattgacca tccaggctcg
      901 caaacgcctg taaaccaaag cgtaataaaa tcccggcaag cattgccgcc gcaagcgagt
      961 gcggaataat gcgcatcaga cgagcaaaga gtcccgttat gccgcagagg actattaacg
     1021 cgttggtgac aataaaaacg ccgatggttt cgttaagtgt tagtccctgc aatccggtga
     1081 ccaacaaagc cgcgccaggc gttgaccatg cggtgagaac aggtacgcga taccataatg
     1141 tcagagccag cgtactgacg cccattgcca gccccagcgc cgtcatccag ccagagattt
     1201 gtgcagtggt ggctccggcg acaatcgctg cttgccagat tattgccgct gaactggcgt
     1261 agccaattaa taccgccaga aaccccgcca gtagcgtggg cggaggaata gaaaacagac
     1321 gcatagtcac ctcgtgcgtt atagcataca ggcaccgtag catttgtccg ttataacgca
     1381 caagtgataa acttacgttt tgccggagga gtcgcatgga aaatctcgct cgctttttat
     1441 ccaccacact taaacaacta cgtcagcagc gcggctggag tctttcgcga ctggcagaag
     1501 cgacgggcgt ttctaaagcg atgttagggc agattgagcg taatgaatcc agcccgacgg
     1561 tcgcgacatt atggaaaata gccaccgggt tgaacgtgcc attttcgaca tttatttctc
     1621 cgccgcagtc cgcaacgcct tcagtttatg atccacaaca acaggcgatg gtgatcactt
     1681 cgctgtttcc ttatgatcca caactctgct ttgaacactt ctcgattcag atggcacccg
     1741 gtgcaataag cgaatcgacg ccccatgaga agggagtaat cgaacatgtt gtcgtcattg
     1801 atgggcaact tgatctgtgc gttgatggtg aatggcagag ccttaattgt ggggaaggcg
     1861 ctcgatttgc tgcagacgtc acgcatgtct attgtaatgg tggggagcaa atcgtacatt
     1921 ttcattccct catccattac ccacgcagtt aagcgggaaa actatttcgc aacgtcgcgc
     1981 ttgtggctaa aatagccgcc atttttcagc tactggataa gaatgtgacc gtatcttctc
     2041 atcgacttga actgttaagc ccggcacgcg atgccgccat tgcccgcgaa gctattttgc
     2101 acggtgccga tgctgtttat atcggcggcc ctggttttgg tgcccgtcat aatgccagta
     2161 atagcctgaa agatattgcc gagctggtgc cgtttgccca tcgttatggt gcaaaaattt
     2221 tcgtcacgct taacacaatt ttgcatgatg atgagctgga acccgcgcaa cggctgatta
     2281 ctgacctcta ccagaccggc gtcgatgcgc tgattgttca ggatatgggg attctggaac
     2341 ttgatattcc gccgattgaa ctgcacgcca gtacgcagtg cgatattcgc acagtagaaa
     2401 aagcgaagtt cctctctgat gttggcttta cgcagattgt gctggcgcga gagctgaatc
     2461 ttgagcagat ccgcgcgatt caccaggcca cggacgcgac cattgaattc tttattcatg
     2521 gcgcactgtg cgtggcctat tcgggtcagt gctacatttc tcatgcgcaa acagggcgta
     2581 gcgccaaccg tggcgattgc tcgcaggcgt gccgtttgcc atacacattg aaagacgatc
     2641 aggggcgggt ggtttcctat gaaaaacatc tgctgtcgat gaaagataac gatcagactg
     2701 ccaacctcgg cgcgctgatt gatgctggcg tacgctcctt caagattgaa gggcgttaca
     2761 aagatatgag ctacgtgaag aatatcaccg cccattatcg ccagatgctg gatgccatta
     2821 ttgaagaacg tggcgatctg acgcgtgctt catcaggtcg tactgaacat ttctttgttc
     2881 catcgacgga aaagactttc caccgtggta gcacagatta ttttgtgaat gcccgtaaag
     2941 gcgatattgg cgcgttcgat tcgccgaaat ttatcggcct gccggtgggc gaagtattga
     3001 aagtagcgaa agatcatatt gatgttgccg ttaccgagcc actggcaaat ggcgatggcc
     3061 tgaacgtgat gattaaacgt gaagtcgtcg gttttcgtgc caatacggtc gagaaaaccg
     3121 gagaaaatca gtaccgcgtc tggcccaatg aaatgccagc agatttgcac aaaattcgcc
     3181 cgcatcaccc actaaaccgt aatcttgatc ataactggca gcaggcactg acaaaaacct
     3241 ccagcgaacg tcgggtggcg gtagacattg aactgggcgg ctggcaggaa caactgattc
     3301 tgaccctcac cagtgaagag ggtgtcagca tcacgcatac gctggacggg cagttcgacg
     3361 aagccaataa cgccgaaaaa gcaatgaaca atctaaagga tggtctggca aaactggggc
     3421 aaaccatcta ttacgcccgc gatgtgcaaa ttaatttgcc gggtgcgctg tttgtaccaa
     3481 acagtctgtt aaaccagttc cgccgtgaag ccgccgacat gctggatgct gcacgtcttg
     3541 ccggttacca gcggggcagc cgtaaaccgg ttgctgatcc tgcgccggtt tatccgcaaa
     3601 cgcatctgag tttcctcgcg aacgtataca accagaaagc gcgtgaattt tatcatcgct
     3661 atggtgtgca actgattgac gcggcgtatg aggcacatga agagaagggc gaagtcccgg
     3721 tgatgatcac caagcattgt ctgcgctttg ccttcaatct gtgcccgaaa caggcgaaag
     3781 gcaatatcaa aagctggaag gcgacgccaa tgcaactggt taacggcgat gaagtattaa
     3841 cgctaaagtt tgattgccgc ccatgcgaga tgcacgtcat tggcaaaatc aaaaatcaca
     3901 tactgaaaat gccgttaccg ggaagcgtag tggcatccgt aagtccggat gatctgctga
     3961 aaacattgcc gaagcgaaaa gggtaaaacg tcagttttcg ggttactcac cactcatcaa
     4021 atctgcatga tattgcctgg cgggtaaggc gtcatgccgc atccggcaac aaatgactca
     4081 acgctgtccc gcttctggtt tgcgcgattt ttgccagtaa aaatgctcgc gcaaaccttc
     4141 cgccgactct tccgccacag cacgcaattc atcgctgtcc gcttcatgac gcagctgatg
     4201 atccacattc tttacccaca taaattcatg tcctttgtgc cctgccatga gttgtcctga
     4261 gaacagtgca cacgttaata agacaaccga taacgccttc gaaaacatcc cgccaccttt
     4321 ttctaacctt ttgccgctat gatgccaatc gtttcttgag gttattattc agttttgcaa
     4381 attagcgcaa agaaattctg gaatcttcct tcctgatttt gcattgcatt ctgccgttgc
     4441 ggcgatttag tgctattttc gagcaaatta cacacggagg taaacactaa tgtttacttt
     4501 gttgatatac tcagcggcag ggaggcgatg tgaaacaaag cgagttcaga cgttggctcg
     4561 aatctcaggg cgtcgatgta gcgaatggca gcaaccattt aaaactgagg tttcatggga
     4621 ggcgcagtgt catgccgcgt cacccctgcg atgagattaa agaaccattg cgtaaagcaa
     4681 tcctgaaaca actcggtttg agttaatcgc caattaaaaa ggttaatgac atgcgagaga
     4741 cagtcgaaat tatgcgttat cccgtcactc ttacacccgc gccggaaggc ggttatatgg
     4801 tttcttttgt ggatatccct gaagcgttga cccagggcga aacagttgct gaagcgatgg
     4861 aagcggcaaa agatgcttta ctgaccgcat ttgattttta ttttgaagat aacgagctta
     4921 tcccgttacc ttcgccatta aacagtcacg atcactttat tgaagtgcct ttgagcgtcg
     4981 cctctaaagt attgctgtta aatgcttttt tacagtcaga aatcactcag caagagttag
     5041 ccaggcgaat tggcaaacct aaacaggaga ttactcgcct atttaatttg caccatgcga
     5101 caaaaatcga cgccgtccag ctcgcggcta aggcgcttgg caaagagtta tcactggtga
     5161 tggtttaatt acagttaacg aaaagttgtc atttttaaca actgatatag actgccgaat
     5221 catctgcaca taattacgat tcgataatga aaaaatacca gcagcttgca gaacaattac
     5281 gcgagcagat tgcgtcgggt atctggcaac ccggcgatcg tttgccttcg ttgcgtgacc
     5341 aggtggcgct ttctggcatg agctttatga ccgtgagcca tgcctatcag ttgctcgaaa
     5401 gtcagggata tattatcgcg cgaccgcagt cgggttatta cgttgcgcca caggcaataa
     5461 aaatgccgaa agcgccagtc attccagtca ctcgagatga agcagtcgat atcaacacct
     5521 atatttttga tatgttgcag gccagtcgcg atccgtcggt agttccgttt gcctcggcct
     5581 ttcccgaccc gcgacttttc cccctccaac aactaaaccg ctcgctggcg caggtaagca
     5641 aaaccgccac ggcgatgagc gtgattgaaa acttaccgcc aggaaacgca gaactgcgtc
     5701 aggctattgc tcgtcgctat gccttacagg gcatcaccat ttctcctgat gaaattgtca
     5761 ttactgccgg ggcgttagag gcattaaacc tcagtttgca agcggtaact gaaccgggcg
     5821 attgggtgat agtagagaat ccttgtttct acggcgcgtt gcaggcgctg gagcggttac
     5881 ggctgaaggc gttatcggtg gcgacggacg ttaaagaagg gatagatctt caggcgctgg
     5941 aactggcgtt gcaggagtat ccggtgaaag cgtgctggct gatgactaat agccagaatc
     6001 cactcggatt taccttaaca ccgcaaaaaa aagcacaact ggtggcgttg ctcaatcagt
     6061 acaacgtaac gctgattgaa gatgacgtat acagcgaact ttattttgga cgggaaaaac
     6121 cgctgcctgc gaaagcgtgg gatcgccacg atggcgtttt gcattgctct tcgttttcga
     6181 aatgtctggt gcctggtttt cgtattggtt gggtcgccgc cggaaaacat gcacgtaaaa
     6241 ttcaacgctt gcagttgatg agtacgcttt ccaccagctc accgatgcag cttgcgctgg
     6301 tggattacct ttccacgcgc cgatacgacg cccatcttcg tcgcctgcgt cgccagcttg
     6361 cggaacgtaa acaacgtgcc tggcaggcac tgctgcgtta tctgcctgcg gaagtgaaaa
     6421 ttcatcataa tgacagcggt tattttctct ggctggagct ccccgcgccg ttagatgcgg
     6481 gcgaattaag cctggcagca ctgacgcatc atatcagtat tgcgccgggt aaaatgtttt
     6541 ctaccggtga aaactggtca cgttttttcc gttttaatac cgcgtggcag tggggagaac
     6601 gtgaagaaca ggcggttaaa caattaggca cacttattca agaacggctg taatagcgtt
     6661 taatttaatt cctctcaggt tgggtaatat gaatttcgaa tagcagtcat atttcctaac
     6721 tccttgtcta tactccagaa gataacctta cagacggcat aatgcgcggt agctcacaac
     6781 ctgattaaat tttctcaggg gcgaaggtgt gcctgcaagc cgccgtctat ggttaaacaa
     6841 ggagatattt ttacggcacg gcggctgaac aattaattac gacaggagta agactttatg
     6901 agcaagacat ttgcccgcag cagcctgtgt gcgcttacca tgacattaat gaccgcccac
     6961 gccgccgaac ctcccacaaa tttagataaa ccggaagggc gactggatat tatcgcctgg
     7021 ccgggataca tcgaacgcgg acaaactgat aaacaatacg actgggtaac gcaattcgaa
     7081 aaagagacag gctgcgcggt gaatgtgaaa accgccgcga cttccgatga aatggtcagt
     7141 ctgatgacca aagggggtta cgatctggtt acggcatccg gcgatgcctc gctgcgcctg
     7201 attatgggca aacgcgtgca gccgattaat accgcattga ttcccaactg gaaagcgctc
     7261 gatccgcgcg tggttaaagg cgactggttt aacgttggcg gcaaagttta cggcacacct
     7321 taccaatggg ggccgaacct gctgatgtac aacactaaaa ccttcccgac gccgccgaat
     7381 agctggcaag tggtttttgt tgagcagaat ctgccggacg gcaagagcaa taaaggccgc
     7441 gttcaggctt atgatggccc tatctacatt gcggacgctg cgttgttcgt taaagccact
     7501 cagccacagt tgggcatcag cgatccgtat caactcaccg aagaacagta ccaggcggtg
     7561 ctgaaagtgc tgcgcgatca acatagtttg atccatcgct actggcatga cactaccgtg
     7621 caaatgagcg atttcaaaaa cgagggtgtg gttgcttcca gtgcatggcc ctatcaggcc
     7681 aacgccctga aagccgaagg ccagcctgtc gctaccgttt tcccgaagga gggcgttacc
     7741 ggttgggctg ataccaccat gctacatagc gaagcgaaac atccggtttg cgcctacaaa
     7801 tggatgaact ggtcattaac cccaaaagtg cagggcgatg tagcggcctg gtttggctcg
     7861 ctaccggtag tgccgcaagg gtgtaaagcc agtccgttat taggcgagaa aggttgtgaa
     7921 acaaacggtt ttaactattt cgataaaatc gccttctgga aaacgcctat cgcagaaggg
     7981 ggcaagtttg ttccctacag tcgctggacg caggattaca ttgccattat gggtggtcgc
     8041 taacttcgct ggggtgtttt atgacgtacg cagtggagtt tgacaacgtc tcacggttgt
     8101 acggtgacgt gcgcgcagta gatggcgtca gtattgcgat aaaagatggt gagttcttct
     8161 ctatgctggg gccgtccggt tccggcaaaa ccacctgcct gcgcctgatt gctggattcg
     8221 aacaactttc cggcggggct atctctatct ttggtaaacc cgccagcaat ctgccaccgt
     8281 gggagcggga cgtgaatact gtcttccagg actacgcgct atttccgcat atgtcgattc
     8341 ttgacaacgt cgcctacggg ctgatggtca aaggcgtgga taaaaaacag cggcatgcga
     8401 tggcgcaaga ggcgctggag aaagtggcgc tgggttttgt tcagcaacgt aaaccgtcac
     8461 aactttctgg tggtcagcgc cagcgggttg ctatcgccag agcattggtg aatgaaccgc
     8521 gtgtgttgtt gctggatgaa ccgctcggcg cactggatct caaattgcgt gagcagatgc
     8581 aactggaact gaaaaagctg caacagtctc tcggtatcac ttttatcttc gttacccacg
     8641 atcagggcga agcgttatcg atgtccgatc gtgtggcggt tttcaataat ggacgcattg
     8701 agcaggtcga ttccccgcgt gatctctata tgcgcccgcg cacgccgttt gttgccgggt
     8761 tcgtcgggac atcgaatgtt tttgatgcac tgatggcaga caaactttgt ggcatgacgg
     8821 gaagcttcgc cctgcgaccg gaacatatcc gcttcaacat ccccggcgaa gtgcaggcta
     8881 atggcacgat ccaggcggtg cagtatcagg gcgcggcgac ccgttttgaa ctgagactga
     8941 acggcggtga aaaactgctg gtgagtcagg ccaatatgac aggcgaagaa ctgcccgcca
     9001 cactcacgcc cggaaaacag gtgatggttt cctggtcgcg tgatgtgatg gtaccgctgg
     9061 ttgaggagag gtgaatggcg atgaacgtat tgcaatcacc ttcacatcca ggtctgggta
     9121 aggtgtccgg tttcttctgg cgtaatccgg ggctggggct gtttttactg ctgcttggcc
     9181 cgctaatgtg gtttggcatt gtctatttcg gctcgctgct gacactgtta tggcagggat
     9241 tttatacctt tgacgatttc accatgtcgg taacgccgga actgacgctg gccaatatcc
     9301 gtgcgctgtt taatccggcg aattacgaca tcattctccg cacgctgatt atggctgtgg
     9361 cagtcactat cgccagcgcc attctggctt ttccaatggc gtggtatatg gcgcgctata
     9421 ccagcgggaa aatgaaagcg tttttttata tcgcggtaat gttgccgatg tgggcgagct
     9481 acattgtgaa agcctatgcc tggacgttat tgcttgcaaa agatggcgtg gcgcagtggt
     9541 ttttacaaca tctggggctg gaaccactgc tgacggcgtt ccttacatta cctgcggtgg
     9601 gcggcaatac gctgtcaact tccgggctgg ggcgctttct ggtgtttctc tatatctggc
     9661 tgccgttcat gatcctgccc gtgcaggcgg cgcttgagcg tttgccgccg tcattgttgc
     9721 aggcgtcagc tgatctcggc gcacgtccac gacaaacctt tcgctatgtg gtgctgccgc
     9781 tggcgatccc gggtattgct gctggctcta tctttacctt ctcactcaca ctgggcgatt
     9841 ttatcgtccc gcagctggtt ggcccgccag gatattttat cggcaatatg gtttattccc
     9901 agcagggggc gattggcaat atgccgatgg cggcggcatt caccctggtg ccgattgttc
     9961 tcatcgcact gtacctggcg ttcgtgaaac gtctgggagc gttcgatgca ctctgaacgc
    10021 gcaccgtttt tcctcaaact ggcggcctgg ggcggcgtgg ttttcctaca ttttcccatc
    10081 ctgattatcg ccgcctatgc gtttaacact gaagatgcgg cgtttagttt tccaccgcaa
    10141 ggcctgacgc tgcgctggtt tagcgtggca gcacagcgta gtgatattct tgatgccgtg
    10201 acactgtcac ttaaagtggc agcgctggcg acattaatcg cgctggtgtt agggacgctg
    10261 gccgctgccg cgctgtggcg acgagacttt ttcggcaaaa acgccatttc gctgttactg
    10321 ctgctgccca ttgcgctgcc gggcattgtc actggtctgg cgctattaac cgcctttaaa
    10381 accatcaatc tggagccggg atttttcacc atcgtggtcg gccatgcgac tttttgcgta
    10441 gtggtggtgt ttaacaatgt catcgcccgt tttcgccgca cctcgtggag tctggttgag
    10501 gcgtcaatgg atcttggggc caatggctgg caaaccttcc gctacgtagt gttgccgaat
    10561 ctcagttcgg cgctactggc aggaggaatg ctggcgtttg ccttgtcgtt cgatgaaatc
    10621 atcgtgacga cctttacggc aggtcatgaa cgaacgttac cgttgtggtt gctcaatcag
    10681 cttgggcgac cgcgtgatgt accggtaacc aacgtggtgg cactgctggt tatgttggta
    10741 acaaccttgc cgatcctggg agcctggtgg ctaacccgcg aaggcgacaa tggtcaataa
    10801 ccactgatac aggaatatgc tatgcaacat aagttactga ttaacggaga actggttagc
    10861 ggcgaagggg aaaaacagcc tgtctataat ccggcaacgg gggacgtttt actagagatt
    10921 gccgaggcat ccgcagagca ggtggatgct gctgttcgcg cggcagatgc agcatttgcc
    10981 gaatgggggc aaaccacgcc gaaagcgcgt gcggaatgcc tgctgaaact ggctgatgtt
    11041 atcgaagaaa atggtcaggt ttttgccgaa ctggagtccc gtaactgtgg caaaccgctg
    11101 catagtgcgt tcaatgatga aattccggcg attgtcgatg tctttcgctt tttcgccgga
    11161 gcagctcgct gcctgaatgg tctggcggca ggtgaatatc ttgaaggtca tacttcgatg
    11221 atccgtcgcg atccgttggg agtcgtggct tctatcgcac cgtggaatta tccgctgatg
    11281 atggcagcgt ggaaactggc tccggcgctg gcggcaggga actgcgtagt gctcaaacca
    11341 tcagaaatta ccccgctgac cgcgttgaag ttggcagagc tggcgaaaga tatcttcccg
    11401 gcaggcgtga ttaacgtact gtttggcaga ggcaaaacgg tgggcgatcc gctgaccgga
    11461 catcccaaag tgcggatggt gtcgctgacg ggctctatcg ccactgggga acacatcatc
    11521 agccataccg cgccgtccat taagcgtact catatggaac ttggtggcaa agcgccagtg
    11581 attgtttttg atgatgcgga tattgaagct gtggtcgaag gtgtacgtac ttttggctat
    11641 tacaatgccg gacaggattg tactgcggct tgtcggctct acgcgcaaaa aggcatttac
    11701 gatacgctgg tggaaaaact cggtgctgcg gtggcaacgt taaaatcggg ttcgccggat
    11761 gacgagtcta cggagcttgg acctttaagc tcgctggcgc atctcgaacg cgtcagcaag
    11821 gcggtagaag aggcgaaagc gacagggcac atcaaagtga tcactggcgg tgaaaagcgc
    11881 aagggtaatg gctattacta tgcgccgacg ctgctggctg gcgcattaca ggacgatgcc
    11941 atcgtgcaaa aagaggtatt tggtccggta gtgagtgtta cgctcttcga caacgaagaa
    12001 caggtggtga attgggcaaa tgacagccag tacggacttg catcctcggt atggacgaaa
    12061 gatgtgggca gggcgcatcg cgtcagcgcg cggctgcaat atggttgtac ctgggtcaat
    12121 acccatttca tgctggtaag tgaaatgccg cacggtgggc agaaactttc tggttacggc
    12181 aaggatatgt cactttatgg gctggaggat tacaccgtcg tccgccacgt catggttaaa
    12241 cattaagggt aatattgcag atcgtaagag tatgagatga tcttgcgtac tgtcagagca
    12301 ctgatttctc tgacagtacg tgctgcgtgc aaaatcacta catcaaataa accagccaaa
    12361 tctcatagag ataagagtaa acaaaccaac agcagcaaag acatttatca gtactacagt
    12421 tctactggaa acattcattt ttgccacctt ttatcattgc ccctatgtgt atagtacggg
    12481 ttaagaaaat ccgcaataat actcattctg aagatggata aggacaagtt gctgtttgat
    12541 gattttttct caaactggtg aaaaaatttg atgcacgtca aaaaatgacg catatttgcg
    12601 cgcgttttat tcatctggct ggacgcccgt acatgtctct ctatcaacac atgcttgttt
    12661 tttatgcggt tatggcagca atcgcatttc ttatcacctg gtttctttct cacgataaga
    12721 aacgcatccg tttcttaagc gcctttctgg tgggggcaac atggccgatg agtttcccgg
    12781 tggcgctgtt gttttcactg ttttaaatct tactcactgg cttgacggca ccacgcagac
    12841 ttatatcatt tggatgaatc gataaatttc acaagtggct aaggagaaag tatgtcgcat
    12901 ctggatgaag tcatcgcgcg cgtggatgcc gcgattgaag agagcgtcat tgcccatatg
    12961 aacgaattat taatcgccct gagcgatgac gcggagttaa gtcgggaaga tcgctacacc
    13021 cagcagcagc gtttgcgcac agcgatcgcc catcacggtc gcaagcataa agaagatatg
    13081 gaagcgcgcc atgaacagtt aaccaaaggc ggcaccatcc tgtgattaaa atgagcgtct
    13141 ggctaccaac caggcgccaa ccacaagtaa aattgcgcca caaattgggc cgaacaacgc
    13201 ccgtagtggt acgccatgac tgcgaaagat atccagcacc agaccgccaa tcagctggct
    13261 ggcgaccagt actgcaatag ttgtcgccgc tcccacattc tgatatccgc tgatactggc
    13321 gaagacaaaa aacgatccca gcaagccagg tataagtgtc caccagcgca cgctggacac
    13381 cagttcgcca aaccccgcca taccttgttt aaaccataaa atagaaacaa agagcacaat
    13441 ccccaccagt gagttcagca acatggcgat gagaatggta gaggaggtct gggtgatgcg
    13501 caccatcagc gtgttctgga ctaccagacc aattccggcg gcaatcaaaa aagcaagggt
    13561 gagcgactga ttcatccaat cgcgtccggt tcagtgcgct cgtcgagttg caactgcata
    13621 aatgtcagat ccagccagcg cccaaattta gtgcccacct gcggcatttg tgcggtgatg
    13681 acaaatccca gcgactggtg gagatgcagc gaagcctgat tttgcgattc gatcccggcg
    13741 accatgacat gcttcccgca atcccgcgct tcatcaatca atcggcttaa caatttacgc
    13801 cccagacctt tgccctgatg atcgggatgg acataaaccg aatgttccac ggtatggcga
    13861 aaaccatcga aactacgcca gtcgccaaac gaggcatatc ccgtcactac gccatcttgt
    13921 tcacttacca gcactggata accagctaaa gtccgcgctt caaaccaggc aatgcgatta
    13981 tctgcatcca ccgtttggtc attccagata gccgccgtat acaacacggc gtggttataa
    14041 atttccgcaa tggcagcaca gtcggctttg cgggcaaaac ggatggacat gtttggcctc
    14101 aataaaataa tgatgatgac gttatcaata ctatcgaaaa cagcccgaag caacggattc
    14161 ctcgatgaaa ttattgcgtg ttgcagaggg gatgtgacgg ctgcaaacaa aaccattcct
    14221 gcgagcctgc tactattgat ggattcatgc caaaagcaca ggagagcatt atggggcaac
    14281 aaaagcagcg taaccgccgt tgggttctgg cctcgcgtcc gcatggcgcg ccggttccgg
    14341 agaatttccg tcttgaagaa gatgatgtcg ccacaccggg tgaaggacag gtgttactgc
    14401 gcacagttta tttgtccctg gacccgtata tgcgtggacg tatgagcgat gagccatctt
    14461 attcaccgcc tgttgatatt ggcggcgtta tggtcggcgg cacggtgagc cgtgtcgtgg
    14521 agtcgaatca tcctgattat cagcctggcg actgggtact gggctacagt ggatggcagg
    14581 actatgacat atccagtggt gatgaactgg tgaaacttgg cgatcatccg caaaatccat
    14641 cgtggtcgct gggtgtgctg gggatgccag gctttactgc ttatatgggc ctactggata
    14701 tcggtcagcc taaagagggc gaaacgctgg tggttgcggc ggcgacagga ccagtagggg
    14761 cgacggtggg gcaaatcggc aaacttaaag gttgcagagt ggtgggggta gccggtggcg
    14821 cggaaaaatg ccgccatgct accgaggtgt taggcttcga tgtttgcctt gatcaccacg
    14881 cggacgattt tgccgaacaa ctggcgaaag cgtgcccaaa aggtattgat atctattatg
    14941 aaaacgtggg cggtaaggta tttgatgcag tgctaccatt acttaataca tctgcgcgca
    15001 ttcccgtttg tggcttagtg agcagctata acgatacaga gctaccaccc ggtccggatc
    15061 gtttacccct gttgatggca acggtgctga aaaaacgcat tcgcttgcaa gggtttatta
    15121 ttagtcagga ttatggtcac cgcatccatg agtttcagca agagatgggg cagtgggtaa
    15181 aagagggaaa aattcactat cgtgaacaag ttaccaacgg tttggagaac gccccacaga
    15241 cgtttattgg cctgctgaac ggcaaaaact tcggtaaagt tgttattcgc gtcgcgggtg
    15301 atgactaaag atacgacggc ggcgtaaagc cgccacaaaa atccaggcaa aaatcttatt
    15361 tccagcttta attaactaac tacatcactg ttcgacggct aataacaata aagatgagtg
    15421 gataatgatt attcagcttc atacgccagg taaacaactt ctgctatacc ggcagagtta
    15481 gaacgaatac acgtgaagga aataacatgc ctggaacgga aaaaataccg catatcagtt
    15541 tgactatgca ggttgagaac gacctgaaac atcagcttag tattggcgca ttaaaacctg
    15601 gcgcacgcct gattactaaa aatctggcgg agcaattagg tatgagtatt acacccgtgc
    15661 gtgaagcatt attacgtctg gtttcggtga atgcgctttc tgtcgcacca gcgcaagcat
    15721 ttacagttcc ggaagtgggg aaacgtcaat tagacgaaat caatcggatt cgctacgaac
    15781 tggaattaat ggcagttact ctggctgttg aaaacctcac cccgcaagac ctggcggaac
    15841 tagaggaatt gctcgagaaa ttacagcagg cgcaagaaaa gggcgacatg gaacaaatca
    15901 ttaatgcgaa caggctattt cgcttagcga tttatcatcg ttcaaatatg cccatcctgt
    15961 gtgaaatgat tgagcaactg tggatcagga tgggacctgg tttacattat ctttatgaag
    16021 cgattaaccc agcggaatta cgtgagcgta tagaaagcta tcatgaacta ctcgccgcgt
    16081 taaaagtaaa agacaaagag ggatgcagtc attgtcttgc tgaaattatg caaaaaaacg
    16141 ttgctatgtt ataccagcaa tataatcgtt aaagtaagtg cccggcaaat accgggcatc
    16201 aaggtaatca ctcaaatcgc cacgcaacat tcacgccgat accataattt cgtccgggcg
    16261 caggttcgta atatcgcccg tttgactcat tgacaatgac agaaccaacg tattctttat
    16321 cgaataaatt atcgacacga ccaaataaat ccacggttaa attgtggtaa ttgtatttat
    16381 acccggtgaa taagccgacg agtgtataag acggcgcttt tgccgtattt tcatcatctg
    16441 ccataatatc gcccatataa cgcgcttccg tgcctgcata ccaaccatct tccggtatat
    16501 aacctatcga cgcaaagccc atattacggg cgatccctgg catccggtta ccgttacaat
    16561 cctgttcatt gcaaacattg ctgcgatagg tcgcatcaag ccaggtccag gacgctttta
    16621 cgcgaaaatc tcccgcgaaa cgttgatccc atgccagttc agcgccttga cgacgggtct
    16681 ttccggcatt tttgtaagtc gtacgcccac cgctactgct atcgacaaca atttcatcat
    16741 cggtgtcggt ctggaacaat gcgagactaa gcagcccatc accaatacgc gttttactgc
    16801 cgatctcaat tgtatcgttg gtggagggtt ttaacccaaa gttcataccg ctttgtccat
    16861 cagcacgata agacagctca ttaatcgtcg gcgtttcaaa acctcgcccg gctgccagat
    16921 agatattcca ggcatcggtc attgcatatt ttaacgaacc ggcaggtagc catttgtgat
    16981 aactggcatc accgctgtca tcgccgttac ccggagtaac gtaatggtcg ttggaatcaa
    17041 accacacgga gctgtagcgc acgccagcat ccagcgacag tttttcgctc agctgccact
    17101 gcgtctgtaa atagggatcg acgttccaca tcagattgcg ttcgtcgcgg cgcaactcac
    17161 ctttttgccc gtattccggc acgccgctat tcaggcggaa gttattgtag cccttgcggt
    17221 tttcactcat gttttcgtag ttcaggccgg tagtgaacgt gagcggaacg cccagttcac
    17281 cacggtgtgt ccagcggctg tctatcccct gataatggcg ttgcagagta atcacgccgc
    17341 ccgcatgtga cgggttaagt tggggagcca tcgggattga ctggtactgg gtcgtttctc
    17401 gctccccggc atacatcatc acactcatct catcccgcga actcaggcta cgctcatagc
    17461 gcaacccagc ctgagtttgc ttgatggttt ttcgcgtgtc gtactgttca gcgcgtggcg
    17521 cttgttgcgg attcgccttc cattctgctt cggttagccc acctgggtca tctgctttga
    17581 tatccacact attgaaaatc aggcttaatt tgctggcgtc atcaatgcgt acgcccagtt
    17641 tggcattggc taaatttttc tgtgcgccac tatggtcacg atagccgtgg gtcgtaaaac
    17701 gcgtggttga gacggtgtaa tcgacatcgc caggctgtgt gccgtcgccc gttgcgcctg
    17761 ttgctttcag cccatagcgc cagctgccaa aactgccgta gtaactactg gcttcaatgg
    17821 ttggtggctg ttgtccggtc tgggtgatga cattcattac accgccagac gcgttgccat
    17881 acagagcaga gaaggggcca cgcagcactt ccacattttg cacactgctt aaatcgatgt
    17941 tggatgtttg cccttgcccg tcgggcatgg tggcgggaat accgtccaca tacaggcgaa
    18001 taccgcgaat tccgtaagtg gagcgggagc caaatccgcg aatcgacagc tgtaaatctt
    18061 gcgcatagtt ctgccggttt tgtacctgca aaccaggcac gccagtcagt gattcagaca
    18121 agttaatgcg cggtgttgcc aggcgcatct cctcgccatc caccacgctc acggctgctg
    18181 gggtatccag ttctgaaatc acctgcggcg cggcactgac aatcatggtc tgttcatcag
    18241 cggcaaaaac aacgggggaa aggacaagca gtgcgggcaa aacggtctgt cggacggaaa
    18301 aaatcttcat gaaaaaagcc aggttaagaa tgggaaaacg ccgtcatggt aataaaattg
    18361 taaatttatg gaaaacgaaa cggcacgata cgttaagtaa ttgagaaaat tgtagtcgta
    18421 acggcaagaa atgctccaca tttgataaaa taatgattac cattcccatt tataacaaaa
    18481 gcgtaacgat gattacgctt agcgaagcat tgtgaagcag caaaaatatc ggttcatcaa
    18541 agggagtcgt catgcattta cgtcatctgt tttcatcgcg cctgcgtggt tcattactgt
    18601 taggttcatt gcttgttgct tcatcattca gtacgcaggc cgcagaagaa atgctgcgta
    18661 aagcggtagg taaaggtgcc tacgaaatgg cttatagcca gcaagaaaac gcgctgtggc
    18721 tcgccacttc gcaaagccgc aaagtggata aaggcggcgt ggtttatcgt cttgatccgg
    18781 ttactctgga agtgacgcag gcgatccata acgatctcaa gccgtttggt gccaccatca
    18841 ataacacgac tcagacgttg tggtttggta acactgtaaa cagcgcggtc acggcgatag
    18901 atgccaaaac gggcgaagtg aaaggccgtc tggtgctgga tgatcgtaag cgcacggaag
    18961 aggtgcgccc gcttcaaccg cgtgagctgg tagctgatga tgccacgaac accgtttaca
    19021 tcactggtat tggtaaagag agcgtgattt gggtcgttga tggcgagaat atcaaactga
    19081 aaaccgccat ccagaacacc ggtaaaatga gtaccggttt agcgctggat agcaaaggca
    19141 aacgtcttta caccactaac gctgacggcg aattgattac catcgacacc gccgacaata
    19201 aaatcctcag ccgtaaaaag ctgctggatg acgacaaaga gcacttcttt atcaacatca
    19261 gccttgatac caccaatcag cgtgcattta tcaccgattc taaagcggca gaagtgttag
    19321 tggttgatac ccgtaatggc aatattcttg cgaaggttgc ggcaccggaa tcactggctg
    19381 tgctgtttaa cccagcgcgt aatgaagcct acgtgacgca tcgtcaggca ggtaaagtca
    19441 gtgtgattga cgcgaaaagc tataaagtgg tgaaaacgtt cgatacgccg actcatccga
    19501 acagcctggc gctgtctgcc gatggcaaaa cgctgtatgt cagtgtgaaa caaaaatcca
    19561 ctaaacagca ggaagctacc cagccggacg atgtgattcg tattgcgctg taatagatat
    19621 ggcgagggtg aaaacggaga gacttgcctg acttttatca cgccgtatcc ggcaccttcg
    19681 tcagtaattt gaatttgccc ggcacgcagc cgggcaattt tgcaattaac tcgccgtttc
    19741 aggtttaaac acaatttcct gtttttcttc atcttcctcg acgactggcg cagtgctgtg
    19801 aatttcagca acgcgtttgc gcacaccaaa ccagcctata accagcagaa taccgataat
    19861 cggcagcgcc gcgatagtat aagtcccgtt cgggtaatcg aacgccatca gcaccagaac
    19921 actcagtaaa aacagtaatg tcagccagga agtgaagggc gcgccaggca gtttaaaact
    19981 gacatccgct gctttgcctt ctttaatcgc tttacgcagg cgcatctggc acacgatgat
    20041 aaacgcccat gaagcgatga ttcccagcga cgcgaagttc aacacaatct caaatacgcg
    20101 cgacggcacc agatagttga ggaatacgcc gacgacatac acaaccagtg tcgccagaat
    20161 cccggcatac ggcacatgct gacgactcat tttcgccata aaactcggtg cggaaccgcc
    20221 catcgccatt gagcgcagaa tgcgtccggt gcagtacaga cctgaattca ggctggagag
    20281 ggcagcggtc agcaccacaa tgttcataat gctgccgata tatggcacac ccagtttaga
    20341 gaaaaacgtc acgaacggac tttgccccgc ctgatacgcg ctccacggca ataacataac
    20401 cagcaacacc acggagccga cgtaaaacag gccaatacgc caaatcacac tgttaatggc
    20461 tttaggcacc atggtctgcg gatctttaca ttctccggca gctgtcccca ccatttcaat
    20521 ggaggcaaaa gcaaacacta cgccctgaat caacaccagc gcaggcagca aaccgtgggg
    20581 gaagaagccg ccattatcgg tgattaaatg aaagccagtg gtgttgccat ccagcggctg
    20641 accactaccg aggaacactg tacccacgac caaaaaggtc acaatggcga gcactttaat
    20701 aagcgcaaac cagaactcca tctccgcaaa ccatttcaca ccgatcatat tcatggtgcc
    20761 aacgatggta agtgcagcga gcgcaaagac ccactgcggc acgccgccaa acgcacccca
    20821 gtaatgcata tacagagcga cggcggtaat atcaacaatc cccgtcatcg cccagttgat
    20881 gaagtacatc cagccagcaa cataagcggc tttctcaccc aaaaactcac gggcataaga
    20941 gacaaaactg ccactggaag ggcggtgtag caccagctca cccaatgcac gcagaataaa
    21001 aaacgaaaac aagccacaaa ttaaataaac cagtgccagt gctggacccg ccatttgcag
    21061 tcgggctcct gcacctaaaa acaagccggt gccaatcgcg ccgccaatgg cgatcatctg
    21121 tacctggcga ttgcccatcg ctttgtgata cccctcttcg tgggcattaa gccagcggcg
    21181 tttcgcggcg tgttgatctg aagtgtcggt gtcgtgttta ctcattgctc tccctgattg
    21241 ctttaatgaa aaagtcatat aagttgccat gaacaatgtt tattcatcct ggcgatgata
    21301 gttatcacca ttattcttta tgggtataaa actatcggcg cagcatccta cccgttatcg
    21361 ataaacgatg caaaacatcc ccttacaatc ctgaagggga ataatacaac tgacgaaaaa
    21421 atgacaaatc cttttgctgg ttaacctgtg tactgtccta cacttaatct ttaaaagatt
    21481 gtgaggggca tatgattaag gtgtatggcg tacccggatg gggctctaca atcagtgagc
    21541 tgatgctaac actggctgat attccttatc agttctttga tgtcagtggt tttgaccacg
    21601 agggaacttc acgcgagtta ttgaaaaccc tgaacccgtt gtgtcagatt ccgacactgg
    21661 cgctggaaaa tgacgagatt atgacggaga cagcggcgat tgcattgatg gttctcgatc
    21721 gtcgcccgga ccttgcgcca ccggttgggc gcgccgaacg tcagcagttt caacggctat
    21781 tggtctggct ggttgctaat gtctatccaa cattcacttt cgccgattac cctgagcgtt
    21841 gggctcctga cgcacctgaa cagttaaaga agaatgttat tgaatatcga aaatcgcttt
    21901 atatctggtt gaattcgcag ctcactgctg aaccttatgc gtttggtgag caactaacgc
    21961 tggtggactg ttatctttgc actatgcgca catgggggcc tgggcatgaa tggtttcagg
    22021 ataatgccac gaatatcagt gcgattgctg atgctgtatg tcagttaccg aaattacaag
    22081 aagtattaaa aaggaatgaa attatttgag tgggatacca gaagattatg ttatttatta
    22141 ttcagtaact ttatccacaa tgatgggcgt aattaattaa attcatgtta tgttttttaa
    22201 tttatatcac tctccctttc attcagcttg tctatttcat ttcctctgaa aagaaactaa
    22261 ctattcacat tgtgcagatg tttcagttgt tatcacaggt attctataat ctcaaaatgt
    22321 ttttaatgat ggatatgctc ggagttggag atgcaattaa tattaataca aataaaaata
    22381 tccggcaggt atgctaaaag gataaatggc gttctctgta tttattcgca attatctgta
    22441 ggacaaatat ggagagcttg atgagtcaga gctaaaacag caattgatta ataaacatgt
    22501 tgatttattc aagaaaatgg atgtatttta aatattgatt cttaatataa cctaatcaat
    22561 agattatcac gtgagagctg cacattattg gaggggcagg ggaaaacacc attttgggaa
    22621 caatgcatca ggtactctta ccactgaagc aagatcatcc gggcaccagg tggtggtgca
    22681 gtgctttgga aatggtcccc tcgggggagt tgtcattatt ttctatgcta tttgcttatt
    22741 atattcatca ggtgaattta ataaattcct aatttgaaat atccactatt aagccagtgt
    22801 ttaacgacgt taagatggca atgtgcagat catgttatca gggtggggcg gtagcgtata
    22861 ttccttatac aaaccatcat tcatttcaat aatgtttatt gagttattta ttattgtgaa
    22921 taaaaagaca ttacaaatat tggtttgact ttgcatatca ggtgtttttt tgttactcga
    22981 tgtaatatac gagcctgtcc ttaataacat cgtgaacccg tcagttgagt ttgtgattat
    23041 tttgttgagt caacagaccc ccgtttctct gaagtaaaat cccggacaaa atcatcacat
    23101 aaccatgaca cttttctgat attcaccggt aacgcctgaa gccggcccgc ttatctcatt
    23161 acccgacatg ttgtacatgc aatatatgca gattattatt cattttcacg gaggttgcta
    23221 tgtcaaccgg attacgtttc acactggaag tggacggcct gccgccggat gcttttgcgg
    23281 tggtttcctt tcatctgaac cagtcactct cttcgctctt ttccctcgat ctctccctgg
    23341 tcagccagca gtttctctcc cttgaatttg cgcaggtgct ggacaaaatg gcctacctga
    23401 cgatatggca gggcgatgaa gtacagcgcc gggtgaaagg cgtggtgacc tggtttgaac
    23461 tgggggagaa cgacaaaaac cagatgctgt acagcatgaa ggtgcacccg ccgctgtggc
    23521 gtgccggtct gcgccagaac ttccgtatct tccagaacga ggacatcaaa agcatcctcg
    23581 gcacgatgtt gcaggaaaac ggggtgaccg aatggagtcc gctgttcagc gagccgcatc
    23641 cttcccgtga gttttgtgtc cagtacggtg agactgatta cgatttcctg tgccggatgg
    23701 cggcggagga aggcatcttc ttttatgagg agcatgctta caaaagtacc gaccagagcc
    23761 tggtgctgtg cgacacagtc cgccatctgc ccgaatcttt tgaaatccca tggaacccga
    23821 acacccgtac cgaggtgagc accctctgca tcagccagtt ccgctacagc gcacaaatcc
    23881 gcccttcttc cgtggtgacc aaagactaca cctttaaacg ccccggctgg gccggacgtt
    23941 ttgaacagga aggccagcac caggactacc agcgcacgca gtatgaagtg tatgactacc
    24001 ccggacgttt caagggtgcc cacgggcaga actttgcccg ctggcagatg gacggctggc
    24061 gaaacaatgc agaaaccgcg cggggaatga gtcgctcgcc ggagatatgg ccgggacgac
    24121 gaattgtgct gacggggcat ccgcaggcga acctgaaccg ggaatggcag gtggtggcaa
    24181 gtgaactgca cggcgaacag ccacaggcgg tgccaggacg gcagggagcg gggacggcgc
    24241 tggagaacca ttttgcggtg atcccggcag acagaacatg gcgaccacag ccgttgctga
    24301 aaccgctggt cgacggcccg cagagcgctg tcgtgacagg accggcaggc gaggaaatct
    24361 tctgcgacga acatggtcgc gtgcgggtga agttcaactg ggaccgttat aacccggcag
    24421 accaagacag ttcgtgctgg atccgtgtgg cacaggcgtg ggcaggcacc ggttttggcc
    24481 acctggcgat accgcgtgtg ggtcaggaag tgattgtaga cttcctcaac ggcgatccgg
    24541 accagccgat cattatgggg cgcacctacc accaggaaaa ccgcaccccc ggcagcctgc
    24601 cgggaacaaa gacgcagatg accatccgct ccaaaacgta catgggcagc ggatttaatg
    24661 agctgaagtt tgatgatgcg acagggagag aacaggtcta catccacgcg cagaagaaca
    24721 tggataccga agtgctcaac gaccgtacca ccaccgtaaa acacgatcac cgcgaaaccg
    24781 taaaaaatga ccagacggtc acgatccagg aaggtaaccg ccttcttacg gtggaaaaag
    24841 gccacaagat caccggagta ctgaaagggt ctttatctga ggacgtcttt caggacagag
    24901 gcacgattgc cggttcggtg catgttgacg ctgtaaacaa tggtggcgaa ggcgacggta
    24961 tacaggctta tacggcgatt aaggaaattt tgctggccgt ggaggaaagc aaaattgcgc
    25021 tgacgccgga tggcatacag ctacaggtcg gggaatcgac ggtaatcagg ctgtcgaagg
    25081 atggcatcac catcgtgggc ggttctgttt tcatcaactg attcactcag attaacaggg
    25141 agtattttat gcagttcact tttaatgaag gccacattca actgccgtct caatggcagg
    25201 atcagtcaat gcaggtccta gtgtccacag ataacagtgg catcaacctg gtcattaccc
    25261 gcgaagccgt tccacaggga accctgacac cagagctgta ccaggaaacg ctggcgctgt
    25321 accagggcaa acttgatggg tacaccgaac atgcctgccg ggaaatcact ctggcagagg
    25381 ccccggcctg gctgctggat tattcctgga acggtccgga agatgaaggg aatcaggggc
    25441 ggattagcca gatagccgta ttccagcggc gtggagatac gctgctgacc ttcactttca
    25501 gcacctcctt atccctgaag aacagtcaaa agacgatgct gctggaggtg ataaagagct
    25561 tcaccccgtt gccaccggag aatgacatcc aaaaggacca gccgcgctga cataaacgag
    25621 ggataacaca tgagtgaagg accaggcggg ccacagggag cgaccgcagg cggtacgctg
    25681 gcaatgcgaa tgctgtcaca gcaggcgatg gtcgccagcc agatgaaacg ggcagccaac
    25741 gacaaagcca ttgcacagat gttggcatca aaaaagtctg gcccccccgc agccaggctg
    25801 ggcgatgaaa ttcagcacaa gagttttttg ggggcgctgg caggggccgt gctgggggcg
    25861 atagtgacca tcgcagaagg ttgcctgatt atggccgcct gtgccaccgg cccttatgcg
    25921 ctggttctgg tgcctgcgct gatgtatgcc agctataagg cgagtgatta tgtggaggag
    25981 aaacagaacc agcttgaatc atggataaac agtttttgtg acacggacgg ggccatcaat
    26041 actggttcta aaaatgtaaa cattaacgga aagcccgctg ccagggccgc cgtcaccctt
    26101 ccccctcctc ccctgactga agcaataccc tctccaccac agggggaacc ctcatggggt
    26161 gatattgcca ctgacctgct tgaatcggca gcggaaaaag cagtaccact ggcgaaggcc
    26221 tgggggaacg ctgttatcac cctgacggac agcaatgccg gtattatgga tcgcgtcagc
    26281 gccggcgcat cgcttctgtt tcccgccggt ccggtattaa tggagtttgc caccatggtg
    26341 ggcgggcgtg gcgaaatcaa aaaagacgtg gatttcccgg aagccggtga ggacacggcg
    26401 ctctgcgaca aggagaacaa accaccgagg atagcccagg gcagcagcaa cgtctttatc
    26461 aacaatcagc ctgccgcacg caaaggggac aaactggagt gcagcgcggc aatcgtggaa
    26521 ggttcgccgg acgtctttat tggcggtgaa caggtgacct atctggatat ccagccggag
    26581 ttcccgccgt ggcagagaat gatcctgggg ggaataacga tagccagcta tcttctgccg
    26641 cccgcgggac tgctgggaaa actggggaat ctggcgaaac tcggcaaact gggaaacctg
    26701 ctggggaaaa gcgggaagct gctgggggca aagctcggcg cgttgctggg gaaaacaggt
    26761 aagtcgttaa aaagtattgc caataaagtc atcagatggg taacagatcc tgtcgatccg
    26821 gtaaccggcg catactgcga cgaacgtacc gactttacgc tgggccagac actccccctc
    26881 tccttcaccc gtttccacag ttctgtactg ccgctgcatg gtctgacggg cgtgggctgg
    26941 agcgactcct ggagcgaata cgcctgggtg cgtgaacagg gaaaccgggt ggatatcatc
    27001 agccagggaa ccacgctgag atttgccttc gacggtgaca gtgatacggc ggttaacccg
    27061 tatcacgccc agtacattct gcgccgccgc gacgattacc tggagctgtt cgaccgtgat
    27121 gcactgagca gccgcttctt ttatgacgcc tttccgggaa tgcgcctgcg ccacccggtg
    27181 actgacgata cctgcgatga ccgtctggca cacagccccg cagaccggat gtacatgctg
    27241 ggcgggatga gcgacaccgc cagcaaccgc atcacgtttg agcgcgacag ccagtaccgc
    27301 atcatgggtg tcagtcacac cgacgggatc cggcttaaac tgacgtacca tgccagcggc
    27361 tacctgaaag ccattcaccg tacggataac ggcatacaga tgctggcgac ctacgaacag
    27421 gatgcgcggg ggcggctgac agaagcggat gcgcggctgg actaccacct gttttatgag
    27481 tacgacgctg cggaccggat catccgctgg tccgataacg accagacgtg gagccgtttc
    27541 acctacgatg cacagggccg gtgcgtgacc gtcaccgggg cggagggcta ttacaacgcc
    27601 acgctggact atggtgacgg ctgcaccacc gtgacggacg gcaagggcat tcaccgttat
    27661 tactatgatc ctgacggcaa tattctgcgg gaagcagcgc cggacggcag caccaccatg
    27721 tatgaatggg atgaattcca tcacctgctg gcccgccact cccctgccgg gcgggtggag
    27781 aagtttgaat acaacgccgc acacggtcag ttaagccgtt acacggcggc agacggtgcg
    27841 gagtggcagt actgctatga tgagcgcggc ctgctcagca acatcaccga ccctgccggg
    27901 cagacgtgga cgcagcagtg tgatgaacgc ggcctgccgg taagtctggt gtcgccacag
    27961 ggcgaagaga cccggctggc gtacacgccg caggggctgc tgtcggggat attccgccag
    28021 gatgaacggc gtctgggcat agagtacgac caccacaacc ggccggaaac actcaccgac
    28081 gtgatgggcc gtgaacacca caccgaatac agcggtcacg acctgccggt gaagatgcgc
    28141 ggccccggcg gtcagtcagt gcggttacgg tggcagcagc accataaact gagcggcctt
    28201 gaacgcactg gcaccggcgc ggaaggattt cgctatgacc gccacggcaa cctgctggcc
    28261 tggacggacg gcaacggcgt tgtctggacg atggaatacg gcccgttcga tttgccggtg
    28321 gcgcgaacgg acggtgaagg ccaccgctgg cagtaccgct acgataaaga cacgctgcaa
    28381 ctgacagaag tcatcaatcc gcagggcgag tcataccgtt atattctgga caactgtgga
    28441 cgggtgacgg aagagcgtga ctggggcggc gtggtctggc gttaccgcta tgacgccgat
    28501 ggcctttgta ccgccagggt taacggcctg gaggaaacta tcctctacag ccgggacgcc
    28561 gcaggccgcc tggcagaagt catctcgccg gaaggcaaaa cgcagtatgc ctatgacaaa
    28621 tccggcaggc tgacgggtat cttcagcccg gacggtacat cacagcgcac cggctatgac
    28681 gaacgcgggc gggtgaatgt caccactcag ggccgacggg ccattgaata ccaccacccc
    28741 gatgaacaca ccgtcatccg ctgtatcctg ccaccggaag atgaacgcga cagacacccc
    28801 ggtgaatccc tgctgaaaac cacctaccgc tacaacgccg ccggagaact gacggaggtt
    28861 atcctgccgg gggatgagac gctgacgttc agccgtgatg aggcaggacg tgaagtgctc
    28921 cggcacagta accggggttt tgcctgtgag cagggctgga atgcagccgg tcagcttacc
    28981 agccagcgcg ccggactttt cccggcggaa gccacatggg gcggactgct cccctcactg
    29041 gtgcgggagt accgttacga cagcgcgggc aatatgtcgg ctgtcaccag ccgggaagac
    29101 tacggacggg aaacacggcg ggagtaccgg ctggaccgga acggccaggt cacggcggtg
    29161 acagcctcag gcaccgggct gggctatggc gaaggcgatg agtcctatgg ctatgacagt
    29221 tgtggctacc tgaaggcgca gtcggcgggc aggcaccgga taagcgtgga tactgacatg
    29281 tatcagcgcg gccaccggct gaaacagacc ggaaacacag actacagcta tgacgccgca
    29341 ggccggatgg tcagccgcac cagacaccgt gacggctacc gcccggaaac agagcggttc
    29401 cggtgggaca gccgggacca gctgaccggg tattgcagcg cacagggtga gcagtgggaa
    29461 taccgccacg acgccagcgg caggcggacg gaaaaacgct gcgaccggaa gaaaatccgt
    29521 tttacgtatc tgtgggacgg cgacagtatt gcggaaatgc gggaataccg ggatgataaa
    29581 ctgtacagcg tacggcacct ggtgtttaac ggctttgagc tgctgagtca gcagttcagc
    29641 cgggtacggc agccgcatcc gtccgtggcc ccgcagtggg tgacgcgaac gaatcatgcg
    29701 gtgagcgacc tgacgggccg tccgctggtg ctctttaaca gtgaaggtaa aaccgtctgg
    29761 cgaccggggc agaccagcct gtgggggctg gcactcagcc tgcccgcaga caccggctac
    29821 ccggacccgc gcggggagct ggacccggaa gccgaccccg gcctgctgta tgcggggcag
    29881 tggcaggatg cggaatcggg gctgtgctat aaccggttcc ggtattacga gccggaaacc
    29941 gggatgtacc tggtgagtga tccactgggg ttgctggggg gtgagcagac ttaccggtat
    30001 gtgcctaatc cgctggggta tgttgatcct ttgggattag ctatatgtcc tgtgatgtat
    30061 gattggtata aatacaatcg ttctcaaggt atgacagcag cacaagcgca tcaagcaatt
    30121 aaaaatacct caccgcagga tgtgttaaat tatgctttac atcggcaagg cttgtctggg
    30181 cataactacc ctataaaatt taaagaaaaa ttcaccgtcg gaaattataa atatgaagta
    30241 agggctcatg atgtaaaccc tactgctcca gcagggagta attctgccaa tggccccata
    30301 tataggattg gtagaagcca aagtggaaca aatcctgcga ctaatcaagg ctatggttgg
    30361 gagtatggtt ctcctgatgg cagttggcat catacatctg atttgaaaac taaaagtccg
    30421 aattataatc caggagctgc aaatgatact catataccat tgcctacagg aactattcca
    30481 tgagtgagca aaacataatt aatgatataa agcaccataa ttggaaagaa agttggttgg
    30541 atttttcagt ttttctttat gaacataatc gcttgattat ttccgggagt gatgaccttt
    30601 cttactatca cacactggaa ataataatag acacgccatg ctatattagc ggtgttatgg
    30661 actggtcatg cgatcttaat gaggagttta ttaagctatc aagttgcact gacaatgctc
    30721 gtgaaatgtt agtattagag ttttattcgg aatttgaatt gaaattcaaa gttattgcga
    30781 aaaaaatatc cattaacttt gatactgtat tttattacaa aagagaaaat ttgaagattg
    30841 gtgagagatt agcttactgg attaaataaa aaagagataa agttccgcca cgacagccgt
    30901 gatcggctac cgcagcgccc ggggtgagca gtgggaatac tgccacgacg ccagtggcag
    30961 acggacagag aaacgctgca aacaaaaagc cctccgcatc acatatctgt gggacggcga
    31021 cactattgcg gaaatccggg aataccgcga tgataaactg tacagtgtgc ggtacctggt
    31081 gtttaacggc tttgagctga taagccagca gttcagccgg gtacggcagc cgcacccgtc
    31141 cgtggccccg cagtgggtga cgcggaccag ccatgcggta agcgacctga caggccgccc
    31201 ggtgatgctc tttaacagtc agggtaacgt ggtgtggcgt gcggagcaga ccagcctgtg
    31261 ggggctggca ctcagcgtca gcgcagacag ggactacccg gacccgcgcg gggagcggga
    31321 cgcagaagcg gaccccggtc tgctgtatgc ggggcagtgg cgggatgcgg agtcagggct
    31381 gtgctataac cggttccggt actacgagcc ggagaccggg atgtatctgg tgagtgaccc
    31441 cctgggtgta ttgggtggac taaacactta tggttatgtg ctgaatccgt gttgcttcac
    31501 agatccatta ggtttaggag cctgccctga attaagtaaa atggctcaaa aagttcatga
    31561 tttagctggg ggattacaca gggaaagatc acgtaacgct gcttttttgt actaaataat
    31621 tcgca
//
LOCUS       DADXDL010000059        30692 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.059, whole genome shotgun sequence.
ACCESSION   DADXDL010000059 DADXDL010000000
VERSION     DADXDL010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30692
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.059"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1276)
                     /locus_tag="IRB70_002981"
     CDS             complement(join(<1..796,796..1276))
                     /locus_tag="IRB70_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBC0632868.1"
                     /translation="MSKPKYPFEKRLEVVNHYFTTDDGYRIISARFGVPRTQVRTWVA
                     LYEKHGEKGLIPKPKGVSADPELRIKVVKAVIEQHMSLNQATAHFMLAGSGSVARWLK
                     VYEERGEAGLRALKIGTKRNIAISVDPEKAASALELSKDRRIEDLERQVRFLETRLVY
                     PKKAESLSSSHEKVKVLNELRQFYPLDELLRAAEIPRSTFYYHLKALSKPDKYADVKK
                     RIGEIYHENRGRYGYRRVTLSLHREGKQINHKAVQRLMGILSLKAAIKVKRYRSYRGE
                     VGQTAPNVLQRDFKATRPNEKWVTDVTEFAVNGRKLYLSPVIDLFNNEVISYSLSERP
                     VMNMVENMLDQAFKKLNPHEHPVLHSDQGWQYRMRRYQNILKEHGIKQSMSRKGNCLD
                     NAVVECFFGTLKSECFYLDEFSNISELKDAVTE"
     gene            complement(1575..3644)
                     /gene="glyS"
                     /locus_tag="IRB70_002982"
     CDS             complement(1575..3644)
                     /gene="glyS"
                     /locus_tag="IRB70_002982"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001291772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBC0632869.1"
                     /translation="MSEKTFLVEIGTEELPPKALRSLAESFAANFTAELDNAGLAHGT
                     VQWFAAPRRLALKVANLAEAQPDREIEKRGPAIAQAFDAEGKPSKAAEGWARGCGITV
                     DQAERLTTDKGEWLLYRAHVKGESTEALLPNMVATSLAKLPIPKLMRWGASDVHFVRP
                     VHTVTLLLGDKVIPATILGIQSDRVIRGHRFMGEPEFTIDNADQYPEILRERGKVIAD
                     YEERKAKIKADAEEAARKIGGNADLSESLLEEVASLVEWPVVLTAKFEEKFLAVPSEA
                     LVYTMKGDQKYFPVYANDGKLLPNFIFVANIESKDPQQIISGNEKVVRPRLADAEFFF
                     NTDRKKRLEDNLPRLQTVLFQQQLGTLRDKTDRIQALAGWIAEQIGADVNHATRAGLL
                     SKCDLMTNMVFEFTDTQGVMGMHYARHDGEAEDVAVALNEQYQPRFAGDDLPSNPVAC
                     ALAIADKMDTLAGIFGIGQHPKGDKDPFALRRAALGVLRIIVEKNLNLDLQTLTEEAV
                     RLYGDKLTNANVVDDVIDFMLGRFRAWYQDEGYTVDTIQAVLARRPTRPADFDARMKA
                     VSHFRTLDAAAALAAANKRVSNILAKSDEVLSDRVNASTLKEPEEIKLAMQVVVLRDK
                     LEPYFAEGRYQDALVELAELREPVDAFFDKVMVMVDDKELRINRLTMLEKLRELFLRV
                     ADISLLQ"
     gene            complement(3654..4565)
                     /gene="glyQ"
                     /locus_tag="IRB70_002983"
     CDS             complement(3654..4565)
                     /gene="glyQ"
                     /locus_tag="IRB70_002983"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBC0632870.1"
                     /translation="MQKFDTRTFQGLILTLQDYWARQGCTIVQPLDMEVGAGTSHPMT
                     CLRALGPEPMAAAYVQPSRRPTDGRYGENPNRLQHYYQFQVVIKPSPDNIQELYLGSL
                     KELGMDPTIHDIRFVEDNWENPTLGAWGLGWEVWLNGMEVTQFTYFQQVGGLECKPVT
                     GEITYGLERLAMYIQGVDSVYDLVWSDGPLGKTTYGDVFHQNEVEQSTYNFEYADVDF
                     LFTCFEQYEKEAQQLLALENPLPLPAYERILKAAHSFNLLDARKAISVTERQRYILRI
                     RTLTKAVAEAYYASREALGFPMCNKDK"
     gene            complement(4660..4968)
                     /locus_tag="IRB70_002984"
     CDS             complement(4660..4968)
                     /locus_tag="IRB70_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YsaB family lipoprotein"
                     /protein_id="HBC0632871.1"
                     /translation="MMMNAFFPAMALMVLMALVGCSTPPPVQKAQRVKVDPLRSLNME
                     GLCKDQAAKRYNTGAQKIDVTAFEQFQGSYEMRGYTFRKEQFVCSFDADGHFLHLSMR
                     "
     gene            5143..6138
                     /gene="wecH"
                     /locus_tag="IRB70_002985"
     CDS             5143..6138
                     /gene="wecH"
                     /locus_tag="IRB70_002985"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-acetyltransferase WecH"
                     /protein_id="HBC0632872.1"
                     /translation="MQPKIYWIDNLRGIACLMVVMIHTTTWYVTNAHSVSPVTWDIAN
                     VLNSASRVSVPLFFMISGYLFFGVRSAQPRHFLRIGLCLLFYSAIALLYIALFTSINV
                     EIALKNLLQKPVFYHLWFFFAIAVIYLVSPLIQVKNVGGKMLLVLMVVIGIIANPNTV
                     PQKIDGFEWLPINLYINGDTFYYILYGMLGRAIGMMDTQHKALSWVCAALFATGVFII
                     SRGTLYELQWRGNFADTWYLYCGPMVFICAITLLTLVKNTLDTHTVPGLGLISRHSLG
                     IYGFHALIIHALRTRGIELKNWPILDIIWIFCATLAASLLLSMLVQQIDRNRLVS"
     gene            complement(6180..6617)
                     /locus_tag="IRB70_002986"
     CDS             complement(6180..6617)
                     /locus_tag="IRB70_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312472.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YiaB family inner membrane protein"
                     /protein_id="HBC0632873.1"
                     /translation="MDNKISTYSPAFSIVSWIALVGGIVTYLLGLWNAEMQLNEKGYY
                     FAVLVLGLFSAASYQKTVRDKYEGIPTTSIYYMTCLTVFIISVALLMVGLWNATLLLS
                     EKGFYGLAFFLSLFGAVAVQKNIRDAGINPPKETQVTQEEYSE"
     gene            complement(6663..7004)
                     /locus_tag="IRB70_002987"
     CDS             complement(6663..7004)
                     /locus_tag="IRB70_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632874.1"
                     /translation="MKTSKTVAKLLFVVGALVYLVGLWISCPLLSGKGYFLGVLMTAT
                     FGNYAYLRAEKLGQLDDFFIRVCQLLALITIGLLFIGVLNAPINAYEMVIYPIAFFVC
                     LFGQMRLFRSA"
     gene            complement(7173..8627)
                     /gene="xylB"
                     /locus_tag="IRB70_002988"
     CDS             complement(7173..8627)
                     /gene="xylB"
                     /locus_tag="IRB70_002988"
                     /EC_number="2.7.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulokinase"
                     /protein_id="HBC0632875.1"
                     /translation="MYIGIDLGTSGVKVILLNEQGEVVAAQTEKLTVSRPHPLWSEQD
                     PEQWWQATDRAMKALGVQHSLQDVKALGIAGQMHGATLLDTQQRVLRPAILWNDGRCA
                     QECTLLEARVPQSRVITGNLMMPGFTAPKLLWVQRHEPEIFRQIDKVLLPKDYLRLRM
                     TGEFASDMSDAAGTMWLDVAKRDWSDLMLQACHLSRDQMPALYEGSEITGALLPEVAK
                     AWGMAAVPVVAGGGDNAAGAIGVGMVDANQAMLSLGTSGVYFAVSEGFLSKPESAVHS
                     FCHALPQRWHLMSVMLSAASCLDWAAKLTGLSNVPALIAAAQQADESTEPVWFLPYLS
                     GERTPHNNPQAKGVFFGLTHQHGANELARAVLEGVGYALADGMDVVHACGIKPQSVTL
                     IGGGARSEYWRQMLADISGQQLDYRTGGDVGPALGAARLAQIAANPEKSLIELLPQLP
                     LEQSHLPDAQRYAAYQPRRETFRRLYQQLLPLMA"
     gene            complement(8699..10021)
                     /gene="xylA"
                     /locus_tag="IRB70_002989"
     CDS             complement(8699..10021)
                     /gene="xylA"
                     /locus_tag="IRB70_002989"
                     /EC_number="5.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose isomerase"
                     /protein_id="HBC0632876.1"
                     /translation="MQAYFDQLDRVRYEGSKSSNPLAFRHYNPDELVLGKRMEEHLRF
                     AACYWHTFCWNGADMFGVGAFNRPWQQPGEALALAKRKADVAFEFFHKLHVPFYCFHD
                     VDVSPEGASLKEYINNFAQMVDVLAGKQEESGVKLLWGTANCFTNPRYGAGAATNPDP
                     EVFSWAATQVVTAMEATHKLGGENYVLWGGREGYETLLNTDLRQEREQLGRFMQMVVE
                     HKHKIGFQGTLLIEPKPQEPTKHQYDYDAATVYGFLKQFGLEKEIKLNIEANHATLAG
                     HSFHHEIATAIALGLFGSVDANRGDAQLGWDTDQFPNSVEENALVMYEILKAGGFTTG
                     GLNFDAKVRRQSTDKYDLFYGHIGAMDTMALALKIAARMIEDGELDKRIAQRYSGWNS
                     ELGQQILKGQMSLADLAKYAQEHNLSPVHQSGRQEQLENLVNHYLFDK"
     gene            10387..11379
                     /gene="xylF"
                     /locus_tag="IRB70_002990"
     CDS             10387..11379
                     /gene="xylF"
                     /locus_tag="IRB70_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter substrate-binding
                     protein"
                     /protein_id="HBC0632877.1"
                     /translation="MKIKNILLTLCTSLLLTNVAAHAKEVKIGMAIDDLRLERWQKDR
                     DIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA
                     KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNN
                     AKLFRAGQMKVLQPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS
                     NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAE
                     IAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVVKDGFHKESEL"
     gene            11457..12998
                     /gene="xylG"
                     /locus_tag="IRB70_002991"
     CDS             11457..12998
                     /gene="xylG"
                     /locus_tag="IRB70_002991"
                     /EC_number="7.5.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-xylose ABC transporter ATP-binding protein"
                     /protein_id="HBC0632878.1"
                     /translation="MPYLLEMKNITKTFGSVKAIDNVSLRLNAGEIVSLCGENGSGKS
                     TLMKVLCGIYPHGSYEGDIIFAGEEIQASHIRDTERKGIAIIHQELALVKELTVLENI
                     FLGNEITHNGIMDYDLMTLRCQKLLAQVSLSISPDTRVGDLGLGQQQLVEIAKALNKQ
                     VRLLILDEPTASLTEQETSVLLDIIRDLQQHGIACIYISHKLNEVKAISDTICVIRDG
                     QHIGTRDAAGMSEDDIITMMVGRELTALYPNEPHTTGDEILRIEHLTAWHPVNRHIKR
                     VNDVSFSLKRGEILGIAGLVGAGRTETIQCLFGVWPGQWEGKIYIDGKQVDIRNCQQA
                     IAQGIAMVPEDRKRDGIVPVMAVGKNITLAALNKFTGGISQLDDAAEQKCILESIQQL
                     KVKTSSSDLAIGRLSGGNQQKAILARCLLLNPRILILDEPTRGIDIGAKYEIYKLINQ
                     LVQQGIAVIVISSELPEVLGLSDRVLVMHEGKLKANLINHNLTQEQVMEAALRSEHHV
                     EKQSV"
     gene            12976..14157
                     /gene="xylH"
                     /locus_tag="IRB70_002992"
     CDS             12976..14157
                     /gene="xylH"
                     /locus_tag="IRB70_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylose ABC transporter permease XylH"
                     /protein_id="HBC0632879.1"
                     /translation="MSKSNPSEVKLAVPTSGGFSGLKSLNLQVFVMIAAIIAIMLFFT
                     WTTDGAYLSARNVSNLLRQTAITGILAVGMVFVIISAEINLSVGSMMGLLGGVAAICD
                     VWLGWPLPLTIIVTLVLGLLLGAWNGWWVAYRKVPSFIVTLAGMLAFRGILIGITNGT
                     TVSPTSAAMSQIGQSYLPASTGFIIGALGLMAFVGWQWRGRMRRQALGLQSPASTAVV
                     GRQALTAIIVLGAIWLLNDYRGVPTPVLLLTLLLLGGMFMATRTAFGRRIYAIGGNLE
                     AARLSGINVERTKLAVFAINGLMVAIAGLILSSRLGAGSPSAGNIAELDAIAACVIGG
                     TSLAGGVGSVAGAVMGAFIMASLDNGMSMMDVPTFWQYIVKGAILLLAVWMDSATKRR
                     S"
     gene            14235..15413
                     /gene="xylR"
                     /locus_tag="IRB70_002993"
     CDS             14235..15413
                     /gene="xylR"
                     /locus_tag="IRB70_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator XylR"
                     /protein_id="HBC0632880.1"
                     /translation="MFTKRHRITLLFNANKAYDRQVVEGVGEYLQASQSEWDIFIEED
                     FRARIDKIKDWLGDGVIADFDDKQIEQALADVDVPIVGVGGSYHLAESYPPVHYIATD
                     NYALVESAFLHLKEKGVNRFAFYGLPESSGKRWATEREYAFRQLVAEEKYRGVVYQGL
                     ETAPENWQHAQNRLADWLQTLPPQTGIIAVTDARARHILQVCEHLHIPVPEKLCVIGI
                     DNEELTRYLSRVALSSVAQGARQMGYQAAKLLHRLLDKEEMPLQRILVPPVRVIERRS
                     TDYRSLTDPAVIQAMHYIRNHACKGIKVDQVLDAVGISRSNLEKRFKEEVGETIHAMI
                     HAEKLEKARSLLISTTLSINEISQMCGYPSLQYFYSVFKKAYDTTPKEYRDVNSEVML
                     "
     gene            complement(15521..16345)
                     /locus_tag="IRB70_002994"
     CDS             complement(15521..16345)
                     /locus_tag="IRB70_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein bax"
                     /protein_id="HBC0632881.1"
                     /translation="MILTPIRRYGAMILMLLTLVFSSEVLAKTHTTTASQKSHLTKAS
                     NKQVSSKQEYSRNSAKSSSLPDLRKYPSGTPRKKAFLRTVMPYITSQNAAITAERNWL
                     ISKQYQGQWSPAERARLKDIAKRYKVKWSGNTRKIPWNTLLERVDIIPTSMVATMAAA
                     ESGWGTSKLARNNNNLFGMKCMKGRCTNAPGKVKGYSQFSSVKESVSAYVTNLNTHPA
                     YSSFRKSRAQLRKADQEVTATAMIHKLKGYSTKGKSYNNYLFAMYQDNQRLIAAHM"
     gene            16665..18695
                     /gene="malS"
                     /locus_tag="IRB70_002995"
     CDS             16665..18695
                     /gene="malS"
                     /locus_tag="IRB70_002995"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HBC0632882.1"
                     /translation="MKLAACFLTLLPGFAVAASWTSPGFPTFSEQGTGTFVSHAQLPK
                     GTRPLTLNFDQQCWQPADAIKLNQMLSLQPCSNTPPQWRLFRDGEYTLQLDTRSGTPT
                     LMISIQNAVEPVASLVRECPKWDGLPLTLDVSATFPEGAAVRDYYSQQIAIVKNGQIT
                     LQPAATSNGLLLLERAETDASAPFDWHNATVYFVLTDRFENGDPSNDQSYGRHKDGMA
                     EIGTFHGGDLRGLTNKLDYLQQLGVNALWISAPFEQIHGWVGGGTKGDFPHYAYHGYY
                     TQDWTNLDANMGREADLRTLVDSAHQRGIRILFDVVMNHTGYATLADMQEYQFGALYL
                     SGDELKKTLGERWSDWKPAAGQTWHSFNDYINFSDKTGWDKWWGKNWIRTDIGDYDNP
                     GFDDLTMSLAFLPDIKTESTTASGLPVFYKNKTDTHAKVIDGFTPRDYLTHWLSQWVR
                     DYGIDGFRVDTAKHVELPAWQQLKTEASAALREWKKANSDKALDDKPFWMTGEAWGHG
                     VMQSDYYRHGFDAMINFDYQEQAAKAVDCFAQMDTTWQQMAEKLQDFNVLSYLSSHDT
                     RLFREGGNKAAELLLLAPGAVQIFYGDESSRPFGPTGSDPLQGTRSDMNWQDVSGKSA
                     ASVAHWQKISQFRARHPAIGEGKQTTLSLKQGYGFVREHGDDKVLVIWAGQQ"
     gene            18873..20126
                     /gene="avtA"
                     /locus_tag="IRB70_002996"
     CDS             18873..20126
                     /gene="avtA"
                     /locus_tag="IRB70_002996"
                     /EC_number="2.6.1.66"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--pyruvate transaminase"
                     /protein_id="HBC0632883.1"
                     /translation="MTFSLFGDKFTRHSGITLLMEDLNDGLRTPGAIMLGGGNPAQIP
                     EMQDYFQTLLTDMLESGKATDALCNYDGPQGKTELLTLLAGMLREKLGWDIEPQNIAL
                     TNGSQSAFFYLFNLFAGRRADGRVKKVLFPLAPEYIGYADAGLEEDLFVSARPNIELL
                     PEGQFKYHVDFEHLHIGEETGMICVSRPTNPTGNVITDEELLKLDALANQHGIPLVID
                     NAYGVPFPGIIFSEARPLWNPNIVLCMSLSKLGLPGSRCGIIIANEKIITAITNMNGI
                     ISLAPGGIGPAIMCEMIKRNDLLRLSETVIKPFYYQRVQETIAIIRRYLPEDRCLIHK
                     PEGAIFLWLWFKDLPITTEQLYQRLKARGVLMVPGHNFFPGLDKPWPHTHQCMRMNYV
                     PEPDKIEAGVKILAEEIERAWAESH"
     gene            complement(20165..20638)
                     /locus_tag="IRB70_002997"
     CDS             complement(20165..20638)
                     /locus_tag="IRB70_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBC0632884.1"
                     /translation="MNRFIIADATKCIGCRTCEVACAVSHQENQDCAALSHGEFISRI
                     RVIKDHTYTTAVACHQCEDAPCANVCPVDAISREHGHIFVEQSRCIGCKSCMLACPFG
                     AMEVVSSRKNARAIKCDLCWHRATGPACVEACPTKALQCMDVEKVQRHRLRQQPV"
     gene            complement(20740..21588)
                     /gene="yiaJ"
                     /locus_tag="IRB70_002998"
     CDS             complement(20740..21588)
                     /gene="yiaJ"
                     /locus_tag="IRB70_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator YiaJ"
                     /protein_id="HBC0632885.1"
                     /translation="MGKEVMGKKENEMAQEKERPAGSQSLFRGLMLIEILSNYPNGCP
                     LAHLSELAGLNKSTVHRLLQGLQSCGYVTTAPAAGSYRLTTKFIAVGQKALSSLNIIH
                     IAAPHLEALNIATGETINFSSREDDHAILIYKLEPTTGMLRTRAYIGQHMPLYCSAMG
                     KIYMAFGHPDYVKSYWESHQHEIQPLTRNTITELPAMFDELAHIRESGAAMDREENEL
                     GVSCIAVPVFDIHGRVPYAVSISLSTSRLKQVGEKNLLKPLRETAQAISNELGFTVRD
                     DQGAIT"
     gene            21789..22787
                     /gene="yiaK"
                     /locus_tag="IRB70_002999"
     CDS             21789..22787
                     /gene="yiaK"
                     /locus_tag="IRB70_002999"
                     /EC_number="1.1.1.130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydro-L-gulonate 2-dehydrogenase"
                     /protein_id="HBC0632886.1"
                     /translation="MKVTFEQLKAAFNRVLISRGVDSETADACAEMFARTTESGVYSH
                     GVNRFPRFIQQLENGDIIPDAQPKRITSLGAIEQWDAQRSIGNLTAKKMMDRAIELAA
                     DHGIGLVALRNANHWMRGGSYGWQAAEKGYIGICWTNSIAVMPPWGAKECRIGTNPLI
                     VAIPSTPITMVDMSMSMFSYGMLEVNRLAGRQLPVDGGFDDEGNLTKEPGVIEKNRRI
                     LPMGYWKGSGMSIVLDMIATLLSDGASVAEVTQDNSDEYGVSQIFIAIEVDKLIDGPT
                     RDAKLQRIMDYVTTAERADENQAIRLPGHEFTTLLAENRRNGITVDDSVWAKIQAL"
     gene            22799..23266
                     /locus_tag="IRB70_003000"
     CDS             22799..23266
                     /locus_tag="IRB70_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhcH/YjgK/YiaL family protein"
                     /protein_id="HBC0632887.1"
                     /translation="MIFGHIAQPDPCRLPAAIEKALDFLRAIDFNALEPGVVEIDGKN
                     IYAQIIDLTTREAVENRPEVHRRYIDIQFLAWGEEKIGIAIDTGNNKVSESLLEQRDI
                     IFYHDSEHESFIEMIPGSYAIFFPQDVHRPGCILQTASEIRKIVVKVALTALN"
     gene            23384..23857
                     /gene="yiaM"
                     /locus_tag="IRB70_003001"
     CDS             23384..23857
                     /gene="yiaM"
                     /locus_tag="IRB70_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate TRAP transporter small
                     permease YiaM"
                     /protein_id="HBC0632888.1"
                     /translation="MKKILEAILAINLAVLSCIVFINIILRYGFQTSILSVDELSRYL
                     FVWLTFIGAIVAFMDNAHVQVTFLVEKLSPAWQRRVALVTHSLILFICGALAWGATLK
                     TIQDWSDYSPILGLPIGLMYAACLPTSLVIAFFELRHLYQLITRSNSLTSPPQGA"
     gene            23860..25137
                     /gene="yiaN"
                     /locus_tag="IRB70_003002"
     CDS             23860..25137
                     /gene="yiaN"
                     /locus_tag="IRB70_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter large permease
                     YiaN"
                     /protein_id="HBC0632889.1"
                     /translation="MAVLIFLGCLLGGIAIGLPIAWALLLCGAALMFWLGMFDVQIMA
                     QTLVNGADSFSLLAIPFFVLAGEIMNAGGLSKRIVDLPMKLVGHKPGGLGYVGVLAAM
                     IMASLSGSAVADTAAVAALLVPMMRSANYPVNRAAGLIASGGIIAPIIPPSIPFIIFG
                     VSSGLSISKLFMAGVAPGIMMGATLMLTWWWQASRLNLPRQQKATKREIWHSFVSGIW
                     ALFLPVIIIGGFRSGLFTPTEAGAVAAFYALFVATVIYREMTFATLWHVLIGAAKTTS
                     VVMFLVASAQVSAWLITIAELPMMVSDLLQPLVDSPRLLFIVIMLAILIVGMVMDLTP
                     TVLILTPVLMPLVKEAGIDPIYFGVMFIINCSIGLITPPIGNVLNVISGVAKLKFDDA
                     VRGVFPYVLVLYSLLVVFVFIPDLIILPLKWIN"
     gene            25150..26136
                     /gene="yiaO"
                     /locus_tag="IRB70_003003"
     CDS             25150..26136
                     /gene="yiaO"
                     /locus_tag="IRB70_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diketo-L-gulonate transporter
                     substrate-binding protein YiaO"
                     /protein_id="HBC0632890.1"
                     /translation="MKLRSVTYALFIAGLAAFSTSSMAAQSLRFGYETSQTDSQHIAA
                     KKFNDLLQERTKGELKLKLFPDSTLGNAQAMISGVRGGTIDMEMSGSNNFAGLSPVMN
                     LLDVPFLFRDTAHAHKTLDGKVGDDLKASLEGKGLKVLAYWENGWRDVTNSRAPVKTP
                     ADLKGLKIRTNNSPMNIAAFKVFGANPIPMPFAEVYTGLETRTIDAQEHPINVVWSAK
                     FFEVQKYLSLTHHAYSPLLVVINKAKFDGLSPEFQQALISSAQEAGNYQRKLVAEDQQ
                     KIIDGMKEAGVEVITDLDRKAFSDALGNQVRDMFVKDVPQGADLLKAVDEVQ"
     gene            26140..27636
                     /gene="lyxK"
                     /locus_tag="IRB70_003004"
     CDS             26140..27636
                     /gene="lyxK"
                     /locus_tag="IRB70_003004"
                     /EC_number="2.7.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-xylulokinase"
                     /protein_id="HBC0632891.1"
                     /translation="MTQYWLGLDCGGSWLKAGLYDREGREAGVQRLPLCALSPQPGWA
                     ERDMAELWQCCMAIIRTLLTHSGVSGEQIVGIGISAQGKGLFLLDKNDKPLGNAILSS
                     DRRAMEIVRRWQEDGIPEKLYPLTRQTLWTGHPVSLLRWLKEHKPERYAQIGCVMMTH
                     DYLRWCLTGVKGCEESNISESNLYNMSLEEYDPCLTDWLGIAEINHALPPVVGSAEIC
                     GEITAQTAALTGLKAGTPIVGGLFDVVSTALCAGIEDEFTLNAVMGTWAVTSGITRGL
                     RDGEAHPYVYGRYVNDGQFIVHEASPTSSGNLEWFTAQWGEISFDEINQAVASLPKAG
                     GDLFFLPFLYGSNAGLEMTSGFYGMQAIHTRAHLLQAIYEGVVFSHMTHLNRMRERFT
                     DVHTLRVTGGPAHSDVWMQMLADVSGLRIELPQVEETGCFGAALAARVGTGVYRDFSE
                     AQRDLQHPVRTLQPDMTAHQLYQQKYQRYQHLIAALQGFHARIKEHTL"
     gene            27633..28295
                     /gene="ulaD"
                     /locus_tag="IRB70_003005"
     CDS             27633..28295
                     /gene="ulaD"
                     /locus_tag="IRB70_003005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBC0632892.1"
                     /translation="MSRPLLQLALDHSSLEDAQRDVTLLKDSVDIVEAGTILCLNEGL
                     GAVKALREQCPNKIIVADWKVADAGETLAQQAFGAGANWMTIICAAPLATVEKGHAMA
                     QRCGGEIQIELFGNWTLDDARDWHRIGVRQAIYHRGRDAQASGQQWGEADLARMKALS
                     DIGLELSITGGITPADLPLFKDIRVKAFIAGRALAGAANPVQVAGDFHAQIDAIWGGA
                     RA"
     gene            28288..29148
                     /locus_tag="IRB70_003006"
     CDS             28288..29148
                     /locus_tag="IRB70_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418039.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBC0632893.1"
                     /translation="MRNHPLGIYEKALAKDLSWPERLVLAKSCGFDFVEMSVDETDER
                     LSRLDWSAAQRASLVTAMIETGVAIPSMCLSAHRRFPFGSRDEAVRERAREIMSKAIR
                     LARDLGIRTIQLAGYDVYYEDHDEGTQQRFAEGLAWAVEQAAASQVMLAVEIMDTAFM
                     NSISKWKKWDEMLASPWFTVYPDVGNLSAWGNDVPAELKLGIDRIAAIHLKDTLPVTG
                     QSPGQFRDVPFGEGCVDFVGIFKTLHELNYRGSFLIEMWTEKAKEPVLEIIQARRWIE
                     ARMQEAGFIC"
     gene            29142..29837
                     /gene="araD"
                     /locus_tag="IRB70_003007"
     CDS             29142..29837
                     /gene="araD"
                     /locus_tag="IRB70_003007"
                     /EC_number="5.1.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBC0632894.1"
                     /translation="MLEQLKADVLAANLALPVHHLVTFTWGNVSAVDETRQWMVIKPS
                     GVEYNVMTADDMVVVEIATGKVVEGRKKPSSDTPTHLALYRRYAEIGGIVHTHSRHAT
                     IWSQAGLDLPAWGTTHADYFYGAIPCTRQMTAEEINGEYEYQTGEVIIKTFEERGLNP
                     AQIPAVLVHSHGPFAWGKNAADAVHNAVVLEECAYMGLFSRQLAPQLPAMQNELLDKH
                     YLRKHGANAYYGQ"
     gene            complement(29869..30684)
                     /locus_tag="IRB70_003008"
     CDS             complement(29869..30684)
                     /locus_tag="IRB70_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0632895.1"
                     /translation="MLELSMTLPIKVQNGGLFISRGVGRHPARRLESWEIIFVEKGRL
                     AIQEEERIFLVNAGESLLLWPNRQHVGVEDFPADLKFYWLHFEVKAPDNDPRWLTHLS
                     VPQQTKVADPQVLVALFRQFLSEQEKHQRTPALEFIVLLILQQLTRDARLDEQADGAG
                     TTLAWKAQKLIRTQYHRPLSTALLARELYCNADYLGRVYRRVFHLTLTKAIHRQRVRE
                     AEKLLISEARSLTEVAALCGFNDVGYFRQIFRKHTGLTPAAWKRRYSKEHINS"
BASE COUNT         7553 a         7882 c         7636 g         7621 t
ORIGIN      
        1 tattccgtaa cagcatcctt cagctcgctt atattactga actcatcaag ataaaaacac
       61 tccgacttta aggttccaaa gaaacactcc accacagcat tatccagaca attgcctttt
      121 ctggacatgc tttgtttaat accatgttct ttaaggatat tttgatatct tctcatacga
      181 tactgccatc cctggtcaga gtgcagaaca ggatgctcgt gaggattaag ctttttgaat
      241 gcctgatcga gcatattctc gaccatgttc atcactggtc tttccgaaag gctgtaagaa
      301 ataacttcgt tgttgaagag atctattact ggagacaaat acagcttgcg cccattgact
      361 gcaaattcag taacatcggt aacccacttc tcgtttggcc gcgtagcctt gaaatctctt
      421 tggagaacat tgggggcggt ttgccctacc tctcctctgt aagagcggta tcgcttgacc
      481 ttaatcgctg ccttcagtga gaggattccc atcaggcgct gaacagcttt atggttaatc
      541 tgtttccctt ctcgatgaag agacagcgtt accctacggt atccgtatcg gcctctattc
      601 tcatgataaa tctcaccaat acgcttttta acgtccgcat acttgtcagg cttgctgaga
      661 gcctttagat ggtaataaaa cgtactgcgc ggtatctccg cagccctgag aagctcatca
      721 agaggataaa actgccttag ctcgttgagt actttcactt tttcgtggga tgagctaagg
      781 ctttcagctt ttttagatac acaagccgcg tttcaagaaa tcgaacttgc ctttcaagat
      841 cctcaatgcg tcggtctttt gacagctcca atgctgatgc cgctttttct ggatcaactg
      901 atattgcaat gtttcttttg gtgccaatct tgagcgcgcg taaaccagct tctccgcgct
      961 cttcataaac cttcagccac ctggctacag aaccactacc agcaagcata aagtgagcag
     1021 tagcctgatt aagagacatg tgctgctcga tcacagcttt cacgacctta atacgcaact
     1081 caggatcagc actaacacct ttaggtttgg gaattaaacc tttttctcca tgtttttcat
     1141 agagggcaac ccatgtcctg acctgggttc gggggacacc aaaacgtgcc gagatgatcc
     1201 tgtaaccatc atcagtagtg aagtagtgat tcacgacttc aaggcgcttt tcaaaagggt
     1261 attttggctt tgacatatca ggggctattc catttcatcg tccaacaaaa tgggtgcagt
     1321 acacactttg atttatagtc aggtggggct tttctctgtc tgcctttcgg tgaatacctg
     1381 agacaaacag tctcaagcac ccgtggctat tctagcttaa taagttcgtt tcttctcctt
     1441 gatataatcc taaaaaaatc tcataaaatt aatatatgag acaatcttta ttcagcagaa
     1501 gattattaaa ggttgctcta ttatttagcg ataaaaaagc ctgccagatg gcaggctttt
     1561 taataacgac gttattactg caacagcgaa atatccgcaa ctcgcaggaa taattcgcgc
     1621 agtttctcca gcatggtaag acggttgatt cgcaattctt tgtcatcaac catgaccatc
     1681 actttatcga agaaggcatc aaccggttca cgcagctcag ccagttcgac cagcgcatcc
     1741 tggtaacgac cttcagcaaa gtacggctct agcttgtcac gtagcaccac aacctgcatc
     1801 gccagtttaa tttcttccgg ctctttcaga gtagaggcat tcacgcggtc gctcagcact
     1861 tcgtcagatt tcgccagaat gttagataca cgcttgttcg ccgccgccag tgctgcagct
     1921 gcatccaggg tacggaagtg cgataccgct ttcattcggg catcgaaatc agccggacga
     1981 gtcggacgac gcgccagtac cgcctggatg gtgtcaacgg tgtaaccttc gtcctgatac
     2041 caggcgcgga agcgaccgag cataaagtcg ataacatcat caaccacgtt ggcattagtc
     2101 agcttatcgc catacagacg cactgcttct tcggtcaggg tttgcaggtc aagattgagg
     2161 ttcttctcaa cgataatacg cagcacgcca agtgcggcac gacgcaacgc aaacgggtct
     2221 ttgtcgcctt tcggatgctg gccgataccg aagatacccg ccagagtatc catcttgtca
     2281 gcaatcgcca gcgcacaggc taccgggtta gacggcaggt catcaccggc aaagcgcggc
     2341 tgatactgct cgttcagcgc cacggcaaca tcttccgctt cgccatcgtg acgcgcgtag
     2401 tgcatcccca taacgccctg ggtgtcggtg aactcgaaga ccatgttggt catcaggtcg
     2461 cacttggaca gcaggcccgc acgggttgcg tggttaacgt cagcgccaat ctgttcagca
     2521 atccagccag ccagcgcctg gatgcggtca gttttgtcgc gcagtgtacc cagctgttgc
     2581 tggaacaaca cggtttgcag gcgcggcagg ttatcttcaa gacgtttttt acggtcggta
     2641 ttgaagaaga actcggcatc cgccagacgt ggacgaacga ctttctcgtt accggagata
     2701 atctgctgcg gatctttcga ttcgatgttg gcaacgaaga taaagttcgg cagcagtttg
     2761 ccgtcgttcg catacaccgg gaagtatttc tggtcacctt tcatggtgta aaccagcgct
     2821 tcagacggca ccgcgaggaa tttctcttcg aattttgcgg tcagcacaac cggccattcc
     2881 accagcgaag cgacttcttc caacaggctt tcgcttaagt cagcgttacc gccaatctta
     2941 cgcgccgctt cttcggcatc ggctttaatc ttcgccttac gttcttcgta atcggcgatg
     3001 actttcccgc gctcacgcag aatttccgga tactgatcag cattgtcgat agtgaattcc
     3061 ggctcgccca taaagcggtg gccgcgaatc acgcgatcgg actgaatgcc cagaatggta
     3121 gccggaataa ctttgtcgcc cagcagcagg gtcacggtgt gcaccggacg cacgaagtgc
     3181 acgtcgcttg caccccaacg catcagtttc gggatcggca gtttcgccag cgaagtcgca
     3241 accatattcg gcagcagtgc ttcggtgctt tcgcccttca cgtgggcgcg atacagcagc
     3301 cattcacctt tatcggtagt cagacgctca gcctggtcaa cggtaatacc gcaaccacgc
     3361 gcccagcctt ctgccgcttt gctcggtttg ccttcagcgt cgaacgcctg agcaatcgcc
     3421 gggccgcgtt tttcgatttc acgatccggt tgcgcttccg ccaggttagc tactttcagc
     3481 gccagacgac gcggagcagc aaaccattga acggtgccgt gtgcgaggcc agcgttatcc
     3541 agctccgcag taaagttcgc agcaaaggac tcagccaggc tgcgcagtgc ttttggtggc
     3601 agctcttcag tgccgatttc caccagaaaa gttttctcag acatagccgc ctcttactta
     3661 tctttgttgc acatcgggaa gccgagggct tcacgggaag cgtagtatgc ttctgccact
     3721 gctttggtca gggtgcgaat gcgcagaata tagcgctgac gctcggtgac ggagatggct
     3781 ttacgcgcat ccagcaggtt gaagctgtgg gcggctttca gaatacgctc gtaggctggc
     3841 agcggcagcg gattttccag cgccagcagc tgctgcgctt ctttctcgta ctgctcaaag
     3901 caggtgaaca ggaagtccac atccgcgtat tcgaagttgt aagtggactg ctccacttcg
     3961 ttctgatgga acacgtcgcc gtaggtggtt ttacccagcg ggccgtcgct ccagaccagg
     4021 tcgtaaacgc tgtctacgcc ctgaatgtac attgccagac gttccagacc gtaggtgatc
     4081 tcgccggtaa ccggtttaca ctccagacca ccaacctgct ggaagtaagt gaactgcgtc
     4141 acttccatgc cgttcagcca cacttcccag cccagccccc aggcacccag cgtcgggttt
     4201 tcccagttat cttccacgaa acggatgtcg tggatggtcg ggtccatgcc cagctctttc
     4261 agagaaccaa ggtacagctc ctgaatattg tccggcgatg gcttaatgac cacctggaac
     4321 tgatagtagt gctgtaaacg gttggggttt tcgccgtagc gaccatcggt cgggcgacga
     4381 gaaggctgaa cataagcagc cgccatcggt tctggcccca gcgcgcgcag acaggtcatt
     4441 gggtgagagg ttcccgcgcc gacttccatg tccaatggtt gaacaatggt gcagccctgg
     4501 cgagcccagt aatcctgtaa ggtcaggatc aagccctgga aggtcctggt atcaaacttt
     4561 tgcatattat ttcgtgctgg atacgtgtgg atttaaagga agggatcagt atacccgctg
     4621 gatggaagat atacagtacg aaacgggaaa aagcagggct taacgcatgg aaagatgcaa
     4681 aaaatggcca tctgcgtcaa aagaacagac aaactgctct ttacggaagg tataaccgcg
     4741 catttcgtag ctcccctgaa actgttcaaa tgcggtgacg tcgatttttt gcgcacctgt
     4801 attatagcgt tttgccgcct gatctttgca tagcccttcc atattcaacg aacgcagagg
     4861 atcaaccttt acccgttgtg ctttctgcac gggtggcggt gtagaacaac ccactagcgc
     4921 cataagcacc ataagcgcca ttgccggaaa gaaagcgttc atcatcatta aattaccgtc
     4981 tggtttgcag gtgagtctta ttatttatat cggtatagtg gctgatatct tacgaatttc
     5041 cttaagcctc tataagctgt agtgataaaa ctcagattat tccagtgcgc caaccgaatg
     5101 atttatcggt cagacttttt ttaaccagat acagagacac agatgcagcc caaaatttac
     5161 tggattgata acctgcgagg gatagcgtgt ttaatggtgg tgatgattca caccactacc
     5221 tggtatgtga ccaatgctca tagtgttagc cccgtcacat gggatatcgc caatgttctg
     5281 aattctgcct ctcgtgtcag cgtgccgcta tttttcatga tttccggcta tctctttttt
     5341 ggcgtacgca gcgcccagcc gcgccatttc ttgcgtatcg gcttatgtct gcttttttat
     5401 agcgcaatcg cactgctcta cattgcgcta tttacctcca tcaatgtaga gatagcgctt
     5461 aaaaacctgc tgcaaaagcc tgttttttac cacttatggt ttttcttcgc gattgcggtg
     5521 atttatctgg tttcaccgct gattcaggtg aagaacgtcg gcggaaaaat gttgctggtg
     5581 ctaatggtgg tgattggtat catcgctaac ccaaacaccg tgccgcagaa aatcgacggt
     5641 tttgaatggc tgccaattaa cttatatatc aatggcgata ctttttacta catcctgtat
     5701 ggcatgttgg gccgcgctat agggatgatg gacacacagc ataaagcact gtcgtgggtg
     5761 tgcgccgcac tgtttgcgac gggggttttt attatctctc gcgggacatt atatgaattg
     5821 cagtggcgcg gaaattttgc cgatacctgg tatctttact gtgggccgat ggtttttatc
     5881 tgcgcaatca cgctattgac tctggttaaa aacacgctgg atacacacac tgttcccggg
     5941 cttgggctga tatcacgcca ttctttaggt atatacgggt tccatgcatt gattatccat
     6001 gcgctgcgta cccgggggat tgagcttaaa aactggccaa tactcgatat tatttggatc
     6061 ttttgcgcga cgttggcagc gagtttgtta ctttctatgc tggtacaaca aatcgacaga
     6121 aacagactag tgagttaaat aaaagcccgg tcacattgga ctgaccgggc ttatgtgaat
     6181 tattcgctgt attcttcctg ggtaacctgt gtttcttttg gtgggtttat tccggcatca
     6241 cgaatattct tctgcaccgc tactgcacca aacaagctta agaagaaagc cagtccataa
     6301 aaacctttct cgctgagtaa taacgtcgca ttccacagac ctaccatcag taacgcaaca
     6361 gagataataa agacagtcag gcaggtcata taataaatgg aggtggtcgg tatgccttca
     6421 tacttgtccc gaacggtctt ttgataagac gccgcagaaa acagtcctaa taccagtacg
     6481 gcaaaataat atcctttttc atttaactgc atctctgcat tccatagccc taacagatag
     6541 gtaacgatac caccaacgag agctatccat gacacaatac taaatgccgg tgaataggtt
     6601 gatattttgt tgtccatcac agtattcctt tcattcctga atgtgtaaga ggtttatgtt
     6661 gctcatgccg agcgaaacaa acgcatttga ccaaacaagc agacaaaaaa ggcgatggga
     6721 taaatcacca tttcataagc attgataggt gcgtttaaaa caccgataaa caagagaccg
     6781 atagtgatta acgccagcaa ctggcagacg cggataaaaa aatcatccag ttgcccgagt
     6841 ttttctgcgc gaagatatgc ataattgcca aaagttgctg tcattaacac gccaagaaaa
     6901 tagccttttc cacttaacaa tgggcatgag atccatagcc caaccagata aaccagcgcc
     6961 ccgacaacaa ataatagttt tgccacagtc tttgaggttt tcataacgat ctccatatct
     7021 accagcgata cattacgagt aaccaacgaa agacaaaact gaaaaatgcc attaacaaat
     7081 gattttcaga ataaattcat actaaatatt aattaattac tgagatatat agatgtgaat
     7141 tatcccccac ccggtcaggc aggggataac gtttacgcca ttaatggcag aagttgctga
     7201 tagaggcgac ggaacgtttc tcgtcgtggc tgataagcgg cataacgctg cgcatctggt
     7261 agatgcgact gttctaacgg tagctgcggc aacaactcaa tgagcgattt ctctggattc
     7321 gccgcaatct gcgccagcct tgctgcgccc agtgctggcc ccacatcccc ccccgtacgg
     7381 taatcgagct gctgaccgct gatatccgcc agcatctgac gccagtactc actacgagcc
     7441 ccgccaccaa tcagcgtaac actttgcggt ttaatgccgc aggcatgtac gacatccatg
     7501 ccatctgcca gcgcataacc cacgccttcc agcactgctc gcgccagttc attagcacca
     7561 tgttgatggg tcaaaccaaa gaaaaccccc ttcgcctggg gattgttgtg tggcgtacgt
     7621 tcaccggaaa gataaggcag aaaccagaca ggctcggtac tttcatcagc ctgttgagca
     7681 gccgcgatta aagctggaac attgctcaga ccggttaatt ttgcggccca atccaggcaa
     7741 gaagccgcac tcagcatcac agacattaaa tgccaacgct gcgggagcgc atggcaaaag
     7801 ctgtgtacgg cgctttctgg cttgcttaag aatccttcgc tgacagcaaa atagaccccc
     7861 gacgtcccca gcgataacat tgcctgatta gcatcaacca ttcccacacc aatcgcacca
     7921 gctgcattat cgccaccgcc tgcgacaaca ggcaccgccg ccatacccca cgctttcgca
     7981 acttcaggta gcaaagcacc agtaatttcg ctgccttcgt ataatgcggg catctggtca
     8041 cgagataagt ggcaagcctg cagcatgaga tcgctccagt cacgctttgc gacatccagc
     8101 cacatagtgc cagctgcgtc agacatatcg ctggcaaact cccccgtcat acgcagacgc
     8161 aagtaatctt tcggtaataa tactttatcg atttgacgga atatctccgg ctcatgccgc
     8221 tgaacccata acaatttagg cgcagtaaat ccgggcatca tcaggttgcc ggtaatcacc
     8281 cgcgattgcg gaactcgcgc ttccagcaaa gtgcactctt gcgcacagcg cccgtcgttc
     8341 cacaaaatgg cagggcgtaa cacccgttgc tgagtatcca gtaaggttgc accgtgcatc
     8401 tgtccggcaa tacctaatgc tttaacgtct tgcagagaat gctgaacgcc cagagctttc
     8461 attgcgcgat cagttgcctg ccaccactgt tccgggtctt gttccgacca gagtggatgc
     8521 gggcgcgaaa cggtcagctt ttccgtttgc gcagcaacca cctcaccctg ctcattgagc
     8581 aaaataactt ttacgcccga ggtgccaaga tctatcccga tatacatatc gatcgttcct
     8641 taaaaaaatg cccggtatcg ctactgataa ccgggccaac ggactgcaca gttagccgtt
     8701 atttgtcgaa cagataatga tttaccagat tttccagttg ctcctggcga ccactctgat
     8761 gcaccggaga caaattatgt tcctgagcat atttggctaa atctgccagt gacatttggc
     8821 ctttcaggat ttgctggcct aattcgctat tccagccgga ataacgctgc gcgatgcgtt
     8881 tatccagctc gccatcttca atcatgcgcg ctgcaatttt cagcgccaac gccatcgtat
     8941 ccatcgcgcc gatatgaccg taaaacagat catatttatc agtactttga cgacgtactt
     9001 tggcatcgaa gttcagacca ccggtggtga aaccgcctgc tttgagaatt tcatacatca
     9061 ccagcgcatt ctcttccaca ctgttcggga actggtcggt gtcccagccc agttgcgcat
     9121 cgccacggtt ggcgtcgaca gaaccgaaca ggccaagcgc aatggcggtg gctatttcat
     9181 gatggaaaga gtgacctgcc agcgtcgcgt ggttagcttc aatattcagt ttaatctctt
     9241 tttccagacc aaactgtttc aggaagccat agaccgtcgc agcatcgtaa tcatattgat
     9301 gtttggtcgg ttcttgcggt ttcggttcga taagcaacgt cccctggaaa ccgattttat
     9361 gtttatgctc aaccaccatc tgcataaagc ggcccagctg ttcacgctcc tgacgcaagt
     9421 cggtatttaa cagcgtttcg taaccttcac gaccgcccca caggacatag ttttcaccgc
     9481 ccaatttatg ggttgcttcc atcgctgtaa caacttgcgt tgccgcccaa ctgaagactt
     9541 caggatctgg gttcgtcgcc gcacccgcgc cataacgagg gtttgtaaag cagttagcgg
     9601 ttccccacag cagcttcacg ccgctctctt cttgcttgcc tgccaggaca tcaaccattt
     9661 gcgcaaaatt attgatgtac tcttttaacg acgcgccctc aggggaaaca tccacatcgt
     9721 ggaagcaata aaatggcaca tgtaacttgt ggaaaaactc aaatgcgaca tctgctttac
     9781 gcttcgccaa cgccagtgcc tcaccaggct gctgccacgg acgattaaac gcccccacac
     9841 caaacatgtc cgccccgttc cagcagaagg tgtgccagta gcaggcggca aatcgcaagt
     9901 gctcttccat acgcttgccc aacaccagtt cgtcgggatt gtagtgacgg aatgctaacg
     9961 ggtttgagga ttttgagcct tcataacgaa cgcgatcgag ctggtcaaaa taggcttgca
    10021 tattgaactc cataatcagg taatgccgcg ggtgatggat gatgtcgtaa tattgggcac
    10081 tccctttcag ttgctcaatt atgttatttc acactgctat tgagataatt cacaagtgtg
    10141 cgctcgctcg caaaataaaa tggaatgatg aaactgggta attcctcgaa gagaaaaatg
    10201 caataagtac aattgcgcaa caaaagtaag atctcggtca taaatcaaga aataaaccaa
    10261 aaatcgtaat cgaaagataa aaatctgtaa ttgttttccc ctgtttagtt gctaaaaatt
    10321 ggttacgttt atcgcggtga ttgttactta ttaaagctgt cctctaacta cagaaggccc
    10381 tacaccatga aaataaagaa cattctactc accctttgca cctcacttct gcttaccaac
    10441 gttgcggctc acgccaaaga agtcaaaata ggtatggcga ttgatgatct ccgtcttgaa
    10501 cgctggcaaa aagatcgaga tatttttgtg aaaaaggcag aatctctcgg cgcgaaagta
    10561 tttgtacagt ctgcaaatgg caatgaagaa acacaaatgt cgcagattga aaacatgatt
    10621 aaccggggtg tcgatgttct tgtcattatt ccttataacg gtcaggtatt aagtaacgtt
    10681 gtaaaagaag ccaaacaaga aggtattaaa gtattagctt acgaccgtat gattaacgat
    10741 gcggatatcg atttttatat ttctttcgat aacgaaaaag tcggtgaact gcaggcaaaa
    10801 gccctggtcg atattgttcc gcaaggtaat tacttcctga tgggcggttc gccggtagat
    10861 aacaacgcca agctgttccg cgccgggcaa atgaaagtgt tacaacctta cgttgattcc
    10921 ggaaaaatta aagtcgttgg tgaccaatgg gttgatggct ggttaccgga aaacgcattg
    10981 aaaattatgg aaaacgcgct aaccgccaat aataacaaaa ttgatgctgt agttgcctca
    11041 aacgatgcca ccgcaggtgg ggcaattcag gcattaagcg cgcaaggttt atcagggaaa
    11101 gtagcaattt ccggccagga tgcggatctc gcaggtatta aacgtattgc tgccggtacg
    11161 caaactatga cggtgtataa acctattacg ttgttggcaa atactgccgc agaaattgcc
    11221 gttgagttgg gcaatggtca ggaaccaaaa gcagatacca cactgaataa tggcctgaaa
    11281 gatgttccct cccgcctgct gacaccgatc gatgtgaata aaaacaacat caaagacacg
    11341 gtagttaaag acggattcca caaagagagc gagctgtaag cgttacgccc cggcgcagag
    11401 cgggggcgtg atttctctcc atgccgcgtg aatgaattgg cttaggtgga gtcgttatgc
    11461 cttatctact tgaaatgaag aacattacca aaaccttcgg cagtgtgaag gcgattgata
    11521 acgtcagctt gcggttgaat gctggcgaaa tcgtctcact ctgtggggaa aatgggtctg
    11581 gtaaatcaac gctgatgaaa gtgctgtgtg gtatttatcc ccatggctcc tacgaaggcg
    11641 acattatttt tgcgggagaa gagattcagg cgagtcacat ccgcgatacc gaacgcaaag
    11701 gtatcgccat cattcaccag gaattggccc tggtgaaaga attgaccgta ctggaaaata
    11761 ttttcctggg taacgaaata acccacaatg gtattatgga ctatgatctg atgacgctac
    11821 gctgtcagaa gctgctcgca caggtcagtt tatccatttc acctgatacc cgcgttggcg
    11881 atttaggact tgggcaacaa caactggttg aaattgccaa ggcacttaat aaacaggtgc
    11941 gcttgttaat tctcgatgag ccgacagcct cattaactga gcaggaaacg tcggttttac
    12001 tggatattat tcgcgatcta caacagcacg gtatcgcctg tatttatatt tcgcacaaac
    12061 tcaacgaagt caaagcgatt tccgatacga tttgcgttat tcgcgacggt cagcacattg
    12121 gcacgcgtga tgctgctgga atgagtgaag acgatattat caccatgatg gtcgggcgag
    12181 agttaaccgc gctttaccct aatgaaccac ataccaccgg agatgaaata ttacgtattg
    12241 aacatctgac ggcatggcat ccggttaatc gtcatattaa acgagttaat gatgtctcgt
    12301 tttccctgaa acgtggcgaa atactgggta ttgccggact cgttggtgcc ggacgtaccg
    12361 agactattca gtgcctgttt ggtgtgtggc ccggacaatg ggaagggaaa atttatattg
    12421 acggcaaaca ggtagatatt cgtaactgtc agcaagccat cgcccagggg attgcgatgg
    12481 tacccgaaga cagaaagcgc gacggcatcg ttccggtaat ggcggttggt aaaaatatta
    12541 ccctcgccgc actcaataaa tttaccggcg gtattagcca gcttgatgac gcggcagagc
    12601 aaaaatgtat tctggaatca atccagcaac tcaaagttaa aacgtcgtcc tccgaccttg
    12661 ctattggacg tttgagcggc ggcaatcaac aaaaagcgat cctcgctcgc tgtctgttac
    12721 ttaacccgcg cattctcatt cttgatgaac ccaccagggg tatcgatatt ggcgcgaaat
    12781 acgagatcta caaattaatt aaccaactcg tccagcaggg tattgccgtt attgtcatct
    12841 cttccgaatt acctgaagtg ctcggcctta gcgatcgtgt actggtgatg catgaaggga
    12901 aactaaaagc caacctgata aatcataacc tgactcagga gcaggtgatg gaagccgcat
    12961 tgaggagcga acatcatgtc gaaaagcaat ccgtctgaag tgaaattagc cgtaccgaca
    13021 tccggtggct tttccgggct gaaatcactg aatttgcagg tcttcgtgat gattgcagct
    13081 atcatcgcaa tcatgctgtt ctttacctgg accaccgatg gtgcctactt aagcgcccgt
    13141 aacgtctcca acctgttacg ccaaaccgcg attaccggca tcctcgcggt aggaatggtg
    13201 ttcgtcataa tttctgctga aatcaacctt tccgtcggct caatgatggg gctgttaggt
    13261 ggcgtcgcgg cgatttgtga cgtctggcta ggctggcctt tgccacttac catcattgtg
    13321 actttggttc tgggactgct tctcggtgcc tggaacggat ggtgggtcgc gtaccgcaaa
    13381 gtcccttcat ttattgtcac cctcgcgggc atgttggcat ttcgcggcat actcattggc
    13441 atcaccaacg gcacgactgt ttcccccacc agcgccgcga tgtcacaaat cgggcaaagc
    13501 tatctacccg ccagcaccgg cttcatcatt ggcgcgcttg gcttaatggc ttttgttggc
    13561 tggcaatggc gcggaagaat gcgccgtcag gctttgggtt tgcagtctcc ggcttctacc
    13621 gcagtagtcg gtcgccaggc tttaaccgct atcatcgtat taggcgcaat ctggctgttg
    13681 aatgattacc gtggcgttcc cactcctgtt ctgctgctga cgttgctgtt actcggcgga
    13741 atgtttatgg caacgcggac ggcatttgga cgacgcattt atgccatcgg cggcaatctg
    13801 gaagcagcac ggctctccgg gattaacgtt gaacgcacca aacttgccgt gttcgctatt
    13861 aacggattaa tggtcgccat cgccggatta atcctcagtt ctcgacttgg cgctggttca
    13921 ccttctgcgg ggaatatcgc cgagctggac gcaattgccg catgtgtgat tggcggcacc
    13981 agtctggcag gcggcgtcgg gagcgtggct ggagcggtaa tgggggcatt catcatggct
    14041 tcactggata acggcatgag tatgatggat gtaccgacct tctggcagta tatcgttaaa
    14101 ggtgcgattc tgttgctggc agtatggatg gactccgcaa ccaaacgccg ttcttgattt
    14161 tgataaaaat tttctcaaag ccggtaacgt attaccggtt ttgagttttt gcatgattca
    14221 gcaggaaaag aaccatgttt actaaacgtc accgcatcac attactgttc aatgccaata
    14281 aagcctatga ccggcaggta gtagaaggcg taggggaata tttacaggcg tcacaatcgg
    14341 aatgggatat tttcattgaa gaagatttcc gcgcccgcat tgataaaatc aaggactggt
    14401 taggagatgg cgtcattgcc gacttcgacg acaaacaaat cgagcaagcg ctagctgatg
    14461 tcgacgtccc cattgttggg gttggtggct cgtatcacct tgccgaaagt tacccacccg
    14521 ttcattacat tgccaccgat aactatgcgc tggttgaaag cgcatttttg catttaaaag
    14581 agaaaggcgt taaccgcttt gctttttatg gtcttccgga atcaagcggt aaacgttggg
    14641 ccactgaacg cgaatatgca tttcgtcagc ttgtcgccga agaaaagtat cgcggagtgg
    14701 tttatcaggg gttagaaacc gcgccagaga actggcaaca cgcgcaaaat cggctggcag
    14761 actggctaca aacgctgcca ccgcaaaccg ggattattgc cgttactgac gcccgggcgc
    14821 ggcatattct gcaagtatgt gaacatctac acattcccgt accggaaaaa ttatgcgtga
    14881 ttggcatcga taacgaagaa ctgacccgct atctttcgcg cgtcgctctc tcttctgtcg
    14941 ctcagggcgc acggcaaatg ggctatcagg cggcaaaact gttgcatcga ttattagata
    15001 aagaagaaat gccgctacag cggattttgg tcccaccagt tcgcgtcatt gaacggcgct
    15061 caacagatta ccgctcgctg accgatcccg ccgttattca ggccatgcat tacattcgta
    15121 atcacgcctg taaagggatt aaagtggatc aggtactgga tgcggtgggc atatcacgct
    15181 ccaatcttga gaagcgtttt aaagaagagg tgggtgaaac catccatgcc atgattcatg
    15241 ccgagaagct ggagaaagcg cgcagtctgc tgatttcaac caccttgtca attaacgaga
    15301 tatcgcaaat gtgcggttat ccatcgctgc aatatttcta ctctgttttt aaaaaagcat
    15361 atgacacaac gccaaaagag tatcgcgatg taaatagcga ggtcatgttg tagcgatgat
    15421 gagaattatc ggcgtcgcat caggtaactc agcacaacca cctgatacga gcaaaagcct
    15481 tatccgcctg acaagtcgga taaggctcga ggaaatgcaa ttacatatgc gccgcgatta
    15541 accgttggtt atcctggtac attgcgaaca ggtagttgtt ataactcttc cctttggtcg
    15601 agtagccctt cagcttgtga atcatcgctg tggcagtcac ttcctgatcc gctttacgca
    15661 gttgtgcacg cgatttacgg aacgaagagt aagccgggtg cgtattgagg ttagtgacat
    15721 aggcgctcac cgattctttg acagaactaa actgtgagta ccctttcact ttacccggcg
    15781 cattggtaca acgtcctttc atgcatttca tgccgaacag gttgttgttg ttgcgcgcca
    15841 gctttgacgt tccccaaccg ctttctgctg cagccatcgt cgccaccata ctggtaggga
    15901 taatgtctac gcgttcaagc aaggtattcc acgggatttt tcgcgtatta ccagaccact
    15961 tcaccttgta gcgtttggcg atgtctttca gacgcgcacg ctcagcaggt gaccattggc
    16021 cctgatactg ttttgaaatc agccagttac gttccgcagt aatggccgca ttttggctgg
    16081 taatgtaagg cattacagtc cggagaaacg cctttttcct tggtgttccg gaagggtatt
    16141 ttcgcaaatc aggaagtgaa ctactctttg cactattgcg agaatactct tgtttactgc
    16201 ttacctgttt attactagct ttagttaagt gggacttttg actcgctgtt gttgtgtgcg
    16261 tcttcgctaa cacctcactc gaaaacacca gagtgagtaa cataagaatc atcgccccat
    16321 atcgtcgtat gggagtcaaa atcatcaggt ctcctggtcg gatttaatca ttccaacacc
    16381 ttatattttt tacaaatttg agagttgaat ctcaaatcat atcaaaaata gctgtcaaga
    16441 gcaccccaag gaatagtcca aatctgaaac tatgtcacga gttaacgatt cagattggcg
    16501 ctaaatcgca gaaaatgtgg ggtttatcgc aaaattcagc cgttttttgc gcgcgatcgc
    16561 tcacccttgc ttctcatcct gtggacttac cgctcaggga tgagttttgt ctggcttatc
    16621 gctggcaaac tgtctgaaat cgcagcaata aggactcatt cgccatgaaa ctcgccgcct
    16681 gttttctgac actccttcct ggcttcgccg ttgccgccag ctggacttct ccggggtttc
    16741 ccacctttag cgaacagggg acgggaacat ttgtcagcca cgcgcagttg cccaaaggta
    16801 cgcgtccact aacgctaaat tttgaccaac agtgctggca gcctgcggat gcgataaaac
    16861 tcaatcagat gctttccctg caaccttgta gcaacacgcc gcctcaatgg cgattgttca
    16921 gggacggcga atatacgctg caactagaca cccgctccgg tacaccaaca ttgatgattt
    16981 ccatccagaa cgccgtcgaa ccggtagcaa gcctggtccg tgaatgcccg aaatgggatg
    17041 gattaccgct cacactggat gtcagcgcca cttttccgga gggagccgcc gtccgggatt
    17101 attacagcca gcaaattgcg atagtgaaga acggtcaaat aacgttacaa cccgctgcca
    17161 ccagcaacgg tttactcctg ctggaacggg cagaaactga cgcctctgcc cctttcgact
    17221 ggcataacgc cacggtttac tttgtgctga cagatcgttt cgaaaacggc gatcccagta
    17281 atgaccagag ttacggacgt cataaagacg gtatggcaga aattggcact tttcacggcg
    17341 gcgatttacg cggcctgacc aacaaactgg attacctcca gcagctgggc gtcaatgctt
    17401 tatggataag tgccccattt gagcaaattc acggctgggt cggcggcggt acaaaaggcg
    17461 atttcccgca ttatgcctac cacggttatt acacacagga ctggacgaat cttgatgcca
    17521 atatgggccg cgaagccgat ctacggacac tggttgatag cgcgcatcag cgcggtattc
    17581 gtattctctt tgatgtcgtg atgaaccaca ccggttatgc cacactggcg gatatgcagg
    17641 agtatcagtt tggcgcgtta tatctttctg gtgacgagct gaaaaaaacg ttgggtgaac
    17701 gctggagcga ctggaaacct gccgccgggc aaacctggca tagctttaac gattacatta
    17761 atttcagcga caaaacaggc tgggataaat ggtggggaaa aaactggatc agaaccgata
    17821 tcggcgatta cgacaatcct ggattcgacg atctcactat gtcgctggcc tttttgccgg
    17881 atatcaaaac cgaatcaacg accgcttctg gtctgccggt gttctataaa aacaaaacgg
    17941 atacccacgc taaagtcatc gacggcttta cccctcgcga ttacttaacc cactggttaa
    18001 gtcagtgggt tcgcgactat gggattgatg gttttcgggt cgacaccgcc aaacatgttg
    18061 agttgcccgc ctggcagcaa ctgaaaaccg aagccagcgc cgcgcttcgc gaatggaaaa
    18121 aagctaactc cgacaaagca ttagatgaca agcctttctg gatgaccggt gaagcctggg
    18181 gccacggcgt gatgcaaagt gactactatc gccacggctt cgatgcgatg atcaatttcg
    18241 attatcagga gcaggcggcg aaagcagtcg attgttttgc gcagatggat acgacctggc
    18301 agcaaatggc ggagaaattg caggatttca acgtgttgag ctacctctcg tcgcatgata
    18361 cccgcctgtt ccgcgaaggt ggtaataaag cagcagagtt attgttatta gcgccaggcg
    18421 cggtacaaat cttttatggt gatgaatcct cgcgtccgtt cggccccacc ggttcggatc
    18481 cactgcaagg cacgcgttcg gatatgaact ggcaggatgt tagcggcaaa tctgccgcca
    18541 gcgtcgcgca ctggcagaaa atcagccagt tccgcgcccg ccatcccgca attggcgagg
    18601 gcaaacaaac gacactttcg ctgaagcagg gctacggctt tgttcgtgag catggcgacg
    18661 ataaagtgct ggtcatctgg gctgggcaac agtgactttt ccggcttccc gttcgtcagt
    18721 acctcgggaa gccgccaacc aggataaaat gtcagctcta atcagcgttg caggataaag
    18781 cactgctccc tcttcaacag agcgatttgc accccagcaa atgtagcgtt attgttacct
    18841 tccttgctac agagttcgac agatatcccg ctatgacatt ctcccttttt ggtgacaaat
    18901 ttacccgcca ctccggcatt acgctgctga tggaagatct gaacgacggt ttacgcacgc
    18961 ctggcgcgat tatgctcggc ggcggtaatc cagcgcagat cccggaaatg caagactact
    19021 tccagacgct actgaccgac atgctggaaa gtggcaaagc gactgatgca ctgtgcaatt
    19081 acgacggtcc acaggggaaa acggagctac tcacactgct tgccggaatg ctgcgcgaga
    19141 agttgggttg ggatatcgaa ccacagaata ttgcactaac aaacggcagc cagagcgcgt
    19201 ttttctactt atttaatctg tttgccggac gccgtgccga tggtcgggtc aaaaaagtgc
    19261 tgttcccgct ggcacctgaa tatattggct acgctgacgc cggactggaa gaagatctgt
    19321 ttgtctctgc gcgtccgaat attgaactgc tgccggaagg ccagtttaaa taccacgtcg
    19381 attttgagca tctgcatatt ggcgaagaaa ccgggatgat ttgcgtctcc cggccgacga
    19441 atccaacagg caatgtgatt actgacgaag agttgctgaa gcttgacgcg ctggcgaatc
    19501 aacacggcat tccgctggtg attgataacg cttatggcgt cccgttcccg ggtatcatct
    19561 tcagcgaagc gcgcccgctg tggaatccga atattgtact gtgcatgagt ctttccaagc
    19621 tgggactacc gggttcgcgc tgcggcatta tcatcgccaa tgaaaaaatc atcaccgcaa
    19681 tcaccaacat gaacggcatt atcagcctgg cgcctggcgg tattggtccg gcgataatgt
    19741 gtgaaatgat taagcgtaac gatctgctgc gcctgtctga aacggttatc aaaccgtttt
    19801 attaccagcg tgttcaggaa actatcgcca tcattcgccg ctatttaccg gaagatcgct
    19861 gcctgattca taaaccggaa ggagccattt tcctctggct atggtttaag gatttgccaa
    19921 ttacgaccga gcagctctac cagcgcctga aagcacgggg cgtgctgatg gtgccggggc
    19981 acaacttctt cccagggctg gataaaccgt ggccacatac acatcaatgt atgcgcatga
    20041 actacgtgcc ggagccggat aaaattgagg cgggggtgaa gattctggcg gaagagatag
    20101 aaagagcctg ggctgaaagc cattaatacg ctattccggc gttgagaaac gccggaaaaa
    20161 cgtttcaaac aggctgctgc cgtagccgat gccgctgcac tttctcgaca tccatgcact
    20221 gcaacgcctt tgtcgggcag gcttcaacac aggccggtcc cgtcgcccga tgccagcaca
    20281 gatcgcactt aatcgccctc gcatttttgc gcgaagaaac gacctccatc gcaccaaacg
    20341 ggcaagccag catacagctt ttacagccaa tgcaacgtga ttgttcaacg aaaatatgcc
    20401 catgttcgcg gcttatcgcg tcaacagggc acacatttgc gcacggtgca tcttcacact
    20461 gatgacaggc tactgccgtg gtgtaagtat gatctttaat gacacgaata cgcgaaataa
    20521 actcaccgtg tgacaacgca gcgcaatcct gattctcctg atgcgacact gcgcaagcca
    20581 cttcacaggt acggcaaccg atacatttcg tcgcatccgc aataataaac cggttcatga
    20641 tcactccttt gcactaaaac agcagagtgc cagagagcgc gtctctactg ctttgatcca
    20701 acgaaggaaa tgttaaagtt ttggcacttg tccaaagcgt tatgtgatcg cgccctggtc
    20761 gtccctgaca gtaaatccca gttcattaga aatagcctgc gcggtttcac gcagtggttt
    20821 caggagattt ttctccccca cctgtttcag acgtgatgtc gaaagcgaaa tcgacacggc
    20881 gtacggcacc cgcccatgaa tatcaaacac cggaacagca atacaggaga cgccgagttc
    20941 gttttcttct ctgtccatcg ccgctccgct ttcacgaatg tgcgccagtt cgtcgaacat
    21001 cgcgggcagc tcggtaatgg tattgcgggt taacggctgg atctcatgct gatggctttc
    21061 ccagtatgac ttcacgtagt ccgggtgacc aaacgccatg tagatcttgc ccattgcgga
    21121 acagtagagc ggcatatgct ggccaatata ggcacgggtt cgcagcatcc cggttgtggg
    21181 ttccagctta taaatcaaaa tagcgtgatc gtcttcgcgg ctggagaagt taatagtttc
    21241 accagtggcg atgttcagtg cctcaagatg cggagcggcg atatgaatga tattcagcga
    21301 agacagcgcc ttctgcccga cggcaataaa tttggtggtc aggcggtaac tccctgcggc
    21361 gggcgcggtg gtcacatagc cgcaggattg taatccctgc aataagcgat ggacggtact
    21421 cttatttaaa ccagccagtt ccgaaagatg cgccaacgga caaccgtttg gatagttgct
    21481 caaaatctca atcagcatca acccgcgaaa cagactctgg cttccggctg gacgctcttt
    21541 ttcctgcgcc atctcgttct ctttttttcc catcacttct ttccccattt tgtcgcgtcc
    21601 tgatggtagc gcaaagtgtg ccgtagttca cgatctcgac agataattta taaccacttg
    21661 attcttaagt tttttgaaat tcgtcaatcc gattgctttg ttaaaaagtg atcgatatat
    21721 ttgaaatcaa gtttcgcata ttgaaatttt aagccaaaaa agcgatcaaa aaaacaagga
    21781 aacctgggat gaaagtgaca tttgagcagt taaaagcagc ctttaatcgg gtcttaattt
    21841 cacgcggcgt tgacagcgaa acggctgacg cctgtgcaga gatgttcgcc cgcaccaccg
    21901 aatccggcgt ttattctcac ggcgttaatc gtttccctcg tttcattcaa caactggaaa
    21961 acggcgatat cattcctgat gcccaaccca aacgtataac cagcctcggc gcaattgaac
    22021 agtgggacgc tcagcgttcg atcggtaacc tgacagcgaa aaagatgatg gatcgcgcca
    22081 ttgaactggc tgccgatcac ggtattggtc tggtggcact acgtaatgcc aaccactgga
    22141 tgcgcggcgg cagctacggc tggcaggcgg cggaaaaagg ctatattggc atttgctgga
    22201 ccaactccat cgccgtaatg ccgccgtggg gcgcaaaaga gtgtcgcatc ggcaccaacc
    22261 cgctgatcgt cgccattcct tctaccccaa tcaccatggt cgatatgtcg atgtcgatgt
    22321 tctcttacgg catgttagaa gttaaccgtc tggcaggccg tcagctcccg gtcgatggtg
    22381 gctttgatga tgagggcaat ttgaccaaag aacctggcgt tatcgagaag aatcgccgca
    22441 ttttgccgat gggctactgg aaaggttctg gcatgtcgat tgtgctggat atgatcgcca
    22501 ctctcctttc cgacggcgca tcggttgccg aagtcaccca ggacaacagc gacgaatacg
    22561 gcgtttcgca aatctttatc gccatcgaag tggataaatt gatcgacggc cccacccgcg
    22621 atgccaagct gcaacgcatc atggattacg ttactaccgc tgaacgcgct gacgaaaacc
    22681 aggccatccg cttacccggc cacgaattta ctaccctgct ggccgaaaac cgccgtaacg
    22741 gcatcactgt tgatgacagc gtgtgggcca aaatccaggc gttatgagga gataagtcat
    22801 gatttttgga catatcgcgc agcctgaccc gtgccgtttg cctgccgcca ttgaaaaggc
    22861 gctcgatttt ctgcgcgcca tcgacttcaa cgccctggag ccgggtgttg tcgaaatcga
    22921 cggcaagaat atttatgcgc aaattatcga tttaaccaca cgcgaagcgg tggaaaaccg
    22981 tccggaagtg catcgtcggt atatcgatat tcagtttctg gcgtggggtg aagagaaaat
    23041 cggcattgct attgatacgg gaaataataa agtcagcgaa tcactattag agcagcgcga
    23101 tattattttt tatcacgata gtgaacatga atcatttata gaaatgatac cgggcagcta
    23161 cgctattttc ttcccgcagg atgttcatcg accaggttgt attctgcaaa cagcctctga
    23221 gatacgaaaa attgtggtta aagtcgcatt aacagcgctg aattaatcga ataatcgtct
    23281 acgccagaac gcctgggtaa tgttattgct ctaactatat taataattta ggttgctgca
    23341 catgcaactt gaattatgac agacatagcc tcaaggaata gctatgaaaa aaatacttga
    23401 agcaatactg gcgattaatc tcgccgtact ttcctgtatt gtgtttataa acattatttt
    23461 aagatatggt tttcagacaa gcattttatc tgtagatgaa ttgtcacgtt atttatttgt
    23521 ctggttaaca tttattggcg cgattgtggc ttttatggat aacgcccacg ttcaggtcac
    23581 ctttctggtg gagaaactct cccccgcatg gcagcgacga gtcgctctgg ttacccattc
    23641 cttaatctta tttatttgtg gcgcactggc ctggggcgca acgctaaaaa caattcagga
    23701 ctggagcgat tattcaccga tcctcggttt gcccatcggc ctgatgtatg ccgcttgtct
    23761 gcccaccagc ctcgttatcg cattctttga actgcgtcat ttatatcaac tcatcacgcg
    23821 tagcaattct ctaacgtcgc caccgcaagg agcttaatca tggctgtgct gatttttctg
    23881 ggctgtctgt tgggtggtat tgctatcggt ttgcctattg cctgggcact gttgttgtgc
    23941 ggggcggcgt taatgttctg gctgggcatg tttgatgtcc agatcatggc acaaacgctg
    24001 gtgaacggag ccgacagctt ctccctgctg gcgattccgt tctttgtgct ggcgggtgaa
    24061 atcatgaatg cgggcggctt gtcaaaacgc attgttgacc tgccgatgaa actggtgggg
    24121 cataaaccag gcgggctggg ctacgtcggc gtgctggcgg ctatgattat ggcgagcctt
    24181 tctggttctg ctgttgcgga taccgccgcc gttgccgcgc tattagtgcc gatgatgcgc
    24241 agcgctaact acccggtcaa ccgtgctgcg gggctgattg cctctggcgg cattatcgcg
    24301 ccaattattc ccccttccat tccgtttatt atcttcggcg tttccagcgg attatccatc
    24361 agcaagctgt ttatggcggg tgttgcccca ggcattatga tgggcgcaac gctgatgctc
    24421 acatggtggt ggcaggccag tcgtcttaat ttaccccgtc agcaaaaagc aacgaaacga
    24481 gaaatctggc actcttttgt ttccggtatc tgggcgctat ttcttccggt cattattatt
    24541 ggcggctttc gctccggtct gtttacccct accgaagccg gggccgttgc tgctttctat
    24601 gcgctgtttg tcgccacagt tatttaccgt gaaatgacct tcgccacact ttggcatgta
    24661 ctcattggcg cggcgaaaac cacctcagtg gtaatgtttc tggtggcctc ggcacaagtt
    24721 tctgcctggc tgattaccat tgctgaactg ccgatgatgg tttctgattt actgcaaccg
    24781 ttggtcgatt caccgcgtct gctgtttatc gttattatgc tggctatcct gattgtcggc
    24841 atggtcatgg atttaacgcc gacggtgtta attcttactc cggtattaat gcctttagtt
    24901 aaagaggcag gaatcgatcc gatttatttc ggtgtcatgt ttatcattaa ctgctcaatc
    24961 ggcttaatta caccgcctat cggtaatgtg cttaacgtta tttcaggggt ggcaaaactc
    25021 aaattcgatg atgcagtcag aggcgttttc ccttacgtcc tggttttata ttcattatta
    25081 gtcgtatttg tttttattcc cgatctcatc atcctccctt tgaaatggat taattaaaag
    25141 gaaaatatta tgaaattacg ctctgtaacc tacgcattat tcattgctgg cctggctgca
    25201 tttagtacat cttcaatggc ggcgcaatct ttacgtttcg gttatgaaac ctcacaaacc
    25261 gactcgcaac atattgcggc gaaaaaattc aatgatttat tgcaggagag aaccaaaggc
    25321 gagctgaaat taaaactgtt cccggacagc actctcggta acgcgcaggc gatgatcagc
    25381 ggcgtacgtg gcggcaccat cgatatggaa atgtccggct cgaataactt tgccgggtta
    25441 tcaccagtga tgaacttgct tgatgtccct ttcctgttcc gcgataccgc tcacgcgcat
    25501 aaaacgctcg acggcaaagt cggtgatgat ctgaaagcct cacttgaagg taaaggactg
    25561 aaagtactgg cctactggga aaacggctgg cgcgatgtca ccaactcgcg cgcaccggtt
    25621 aaaacccccg ccgacctgaa agggctgaaa atccgcacca acaatagtcc gatgaatatc
    25681 gcagcattca aagtctttgg cgctaacccg atcccgatgc cgtttgccga agtctatacc
    25741 gggctggaaa cgcgcactat cgacgctcag gaacacccga tcaacgtcgt ctggtcagca
    25801 aaatttttcg aagtacagaa gtacctttct ctgacgcacc acgcctattc gccacttttg
    25861 gtggtgatca acaaagcgaa gtttgatggc ttaagcccgg aattccagca ggcgctgatc
    25921 tcatctgcgc aggaagcggg taactaccag cgcaaactgg ttgccgaaga tcagcaaaaa
    25981 atcatcgacg gcatgaaaga agcgggcgtg gaagtcatca ccgatctcga ccgcaaagcc
    26041 tttagcgacg cactggggaa tcaggttcgc gacatgtttg ttaaagatgt gccgcaggga
    26101 gctgatctgc tgaaagccgt ggatgaggtg caataaacca tgacgcaata ctggctgggg
    26161 ttagattgtg gcggtagctg gctgaaagcc gggctgtatg accgcgaagg ccgggaggca
    26221 ggcgtgcagc gcctgccgct gtgcgcatta agcccgcagc caggttgggc agagcgcgat
    26281 atggcagaac tgtggcaatg ctgcatggct atcattcgca ccctgcttac tcattctggt
    26341 gtcagcgggg aacaaattgt cggtatcggc atctccgcac agggaaaggg cttgtttttg
    26401 ctggataaaa acgacaagcc gctcggtaac gccattttgt cctcggatcg ccgggcgatg
    26461 gaaatcgttc gtcgctggca ggaagatggc atcccggaaa aactctaccc gctgacccga
    26521 caaaccttgt ggaccgggca tccggtgtcg ctgttacgct ggctgaaaga gcacaaacca
    26581 gaacgctacg cgcaaattgg ctgcgtgatg atgacgcacg actacctgcg ctggtgttta
    26641 accggcgtca aaggttgcga agagagcaat atttccgagt ccaatctcta caacatgagt
    26701 cttgaggaat atgacccgtg cctcaccgac tggctgggga tcgctgaaat caaccacgcc
    26761 ctgccgcctg ttgtcggatc tgccgaaatc tgcggggaaa tcaccgctca gacagccgca
    26821 ctgaccggtc tgaaagcggg tacgcccatt gtcggcggcc tgtttgatgt ggtttccacc
    26881 gcactctgtg ccgggatcga agacgaattt acccttaatg cggtgatggg cacctgggcg
    26941 gtgaccagcg gcataacccg tggtttacgt gacggtgaag cgcatccgta tgtctatggt
    27001 cgctacgtta acgatggtca atttatcgtt cacgaagcca gccccacctc ttccggcaac
    27061 ctcgaatggt ttaccgcaca gtggggagaa atctcgtttg atgagattaa ccaggccgtt
    27121 gccagcttgc caaaggccgg gggcgatctc tttttcctgc cgttcctgta cggcagcaac
    27181 gccggactcg agatgaccag cggtttctac gggatgcagg ccattcacac ccgcgcacac
    27241 ctgttgcagg ccatttatga aggcgtggtg ttcagccata tgacccatct caaccggatg
    27301 cgcgaacgtt ttactgatgt gcacaccctg cgcgtcactg gcggcccggc gcactccgat
    27361 gtctggatgc aaatgctggc ggacgtcagc gggctgcgta tcgaactgcc gcaggtggaa
    27421 gaaaccggct gctttggtgc ggcacttgcc gcccgcgtcg gcaccggagt ttatcgcgat
    27481 ttcagcgaag cccaacgtga tttacagcac ccggtacgca ccctgcagcc ggatatgacc
    27541 gcacatcagc tttaccaaca aaaataccaa cgttatcagc atctcattgc cgcacttcag
    27601 ggctttcacg cccgcatcaa ggagcacaca ttatgagccg accacttctg caactggccc
    27661 tcgaccactc atcacttgaa gacgcacagc gcgacgtgac gctgttaaaa gacagcgtcg
    27721 atatcgtcga agcgggcacc attctctgct taaacgaagg gcttggcgca gtgaaagcct
    27781 tgcgcgaaca gtgcccgaac aaaatcatcg tcgctgactg gaaggtcgcc gacgcgggtg
    27841 aaacgctcgc gcaacaggcg tttggcgcag gcgctaactg gatgaccatc atctgcgccg
    27901 caccgctcgc gacggtggaa aaaggccacg cgatggcgca acgctgcggt ggtgaaattc
    27961 agatcgagtt gttcggtaac tggacgctgg acgacgcccg cgactggcat cgtattggcg
    28021 tgcggcaggc catttatcat cgcggtcgcg acgcgcaggc cagcgggcaa cagtgggggg
    28081 aggccgatct ggcacgcatg aaggcgcttt ccgatatcgg ccttgagctt tccattaccg
    28141 gcggtattac tcctgctgat ctgccactgt ttaaagatat ccgcgtaaag gcgtttattg
    28201 ccggacgggc gctggcaggc gcggcaaatc cggtgcaggt ggctggcgat ttccatgcac
    28261 aaattgatgc catctgggga ggtgcgcgtg cgtaatcatc cgttagggat ttatgaaaaa
    28321 gcgctggcga aagatctctc ctggccggag cggctggtgc tggcaaaaag ctgtggcttt
    28381 gattttgtcg aaatgtcggt ggatgaaacc gacgaacggc tctcacgtct tgactggagc
    28441 gccgcacaac gtgcttcgct ggtcactgcg atgatcgaaa cgggtgttgc cattccgtca
    28501 atgtgcctgt ctgcccatcg tcgttttccc tttggcagcc gggacgaggc agtgcgcgaa
    28561 cgggcgcggg aaatcatgag taaagcgatt cgcctggcgc gcgatctcgg cattcgcacc
    28621 atccagctgg caggttatga cgtctattac gaagaccacg acgaaggcac ccaacaacgt
    28681 tttgctgaag ggctggcgtg ggcagtcgaa caggcggcgg catcacaagt catgctggcg
    28741 gtggagatta tggataccgc gtttatgaac tccatcagca aatggaaaaa atgggacgag
    28801 atgctcgcct cgccgtggtt caccgtctac ccggacgtcg gcaacctcag cgcctggggc
    28861 aatgatgttc ccgccgaact gaaactgggc attgaccgta tcgccgcgat ccacctgaaa
    28921 gacaccctgc cagtcaccgg gcaaagcccc ggacagttcc gtgatgtgcc gtttggcgaa
    28981 ggctgcgtcg atttcgttgg catcttcaaa acgctgcatg aactgaacta tcgcggatca
    29041 tttctgattg agatgtggac cgaaaaagcc aaagagccgg tgctggagat tattcaggcg
    29101 cggcgctgga ttgaagcgcg tatgcaggag gccggattta tatgttagag caactaaaag
    29161 ccgacgtgct ggcggcgaat ctggcgcttc ccgttcatca tctggtgacg ttcacctggg
    29221 gcaatgtcag cgcggtagac gaaacgcggc aatggatggt aatcaaacct tccggcgtcg
    29281 agtacaacgt gatgaccgcc gacgatatgg tagtggttga gatagccacc ggtaaggtgg
    29341 tggaaggcag aaaaaaaccc tcgtccgaca cgccaacgca tctggcgctt taccgtcgct
    29401 atgccgaaat tggcggtatt gtgcataccc actcgcgcca cgccaccatc tggtcgcagg
    29461 ccgggctgga tctccccgcc tggggcacca cgcacgctga ttacttctat ggtgccatcc
    29521 cctgcacgcg acagatgacc gcagaggaga tcaacggcga gtatgaatac cagaccggcg
    29581 aagtgatcat taaaaccttc gaagaacgtg ggttgaaccc ggcacaaatc ccggctgtac
    29641 tggtgcattc tcacggcccg ttcgcctggg gaaaaaacgc cgccgatgcg gtgcataacg
    29701 ccgtggtgct ggaagagtgc gcctatatgg gcctgttctc gcgccagctt gcaccgcagc
    29761 tccctgcgat gcaaaacgaa ctgctggata agcactacct gcgtaaacat ggggccaatg
    29821 cctattacgg gcagtaatcc ctcacgccgg ggcttcattg ccccggcact acgaattgat
    29881 atgttccttg ctgtaacgtc gcttccacgc agctggcgtt aagccggtgt gtttgcgaaa
    29941 aatctgccgg aaatagccga cgtcattaaa cccgcacaac gccgccactt ccgtgagcga
    30001 tcgcgcttcg ctaattaaca gcttttcggc ttcgcgcacc cgctggcggt ggattgcttt
    30061 tgttaacgtc agatgaaaca cccgccgata gacgcgccca agataatcgg cattgcagta
    30121 cagctcgcgg gctaaaagcg ccgtggaaag cgggcggtga tattgcgtgc gaatcagttt
    30181 ctgcgctttc caggcaaggg tggtgcctgc accatcggcc tgttcatcaa gacgcgcgtc
    30241 acgggtgagc tgctgcaaaa tcagcagcac aataaactcc agcgccggag tgcgttgatg
    30301 cttttcctgt tcgcttaaga actggcgaaa caaggccacc agcacctgcg gatcggcaac
    30361 cttagtttgt tgcggcacgc taagatgagt gagccagcgc ggatcgttgt ccggcgcttt
    30421 aacctcaaaa tgcagccagt aaaatttgag atcggcggga aaatcctcta ccccaacatg
    30481 ctgtcggttc ggccagagta ataaactctc tcccgcattg accagaaata tccgctcttc
    30541 ttcctgaatc gctaatcgac ctttttcgac aaagataatt tcccatgact ccagccgcct
    30601 tgccggatgc ctcccaacgc cacgggaaat aaataatcca ccattttgca ctttaatcgg
    30661 taacgtcatg gataattcga gcattgatat gt
//
LOCUS       DADXDL010000060        30676 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.060, whole genome shotgun sequence.
ACCESSION   DADXDL010000060 DADXDL010000000
VERSION     DADXDL010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30676)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30676)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30676
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.060"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            157..675
                     /locus_tag="IRB70_003009"
     CDS             157..675
                     /locus_tag="IRB70_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine zipper 2TM domain-containing protein"
                     /protein_id="HBC0632896.1"
                     /translation="MMKFKKCLLPVAMLASFTLAGCQSNADDHAADVYQTDQLNTKQE
                     TKTVNIISILPAKVAVDNSQNKRNAQAFGALIGAVAGGVIGHNVGSGSNSGTTAGAVG
                     GGAVGAAAGSMVNDKTLVEGVSLTYKEGTKVYTSTQVGKECQFTTGLAVVITTTYNET
                     RIQPNTKCPEKS"
     gene            691..1230
                     /locus_tag="IRB70_003010"
     CDS             691..1230
                     /locus_tag="IRB70_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5384 family protein"
                     /protein_id="HBC0632897.1"
                     /translation="MKKVFLCAILASFSYPAIASSLQDQLSAVAEAEQQGKNEEQRQH
                     DEWVAERNREIQQEKQRRANAQAAANKRAATAAANKKARQDKLDAEATADKKRDQSYE
                     DELRSLEIQKQKLALAKEEARVKRENEFIDQELKHKAAQTDVVQSEADANRNMTEGGR
                     DLMKSVGKAEENKSDSWFN"
     gene            complement(1450..1932)
                     /locus_tag="IRB70_003011"
     CDS             complement(1450..1932)
                     /locus_tag="IRB70_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001375980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2514 domain-containing protein"
                     /protein_id="HBC0632898.1"
                     /translation="MIWAFVKAYWKQLLIVVMLAALFIVGVVAWNIHGSRQYDAGYAQ
                     AEEDRKDEEDKVRQYYEQEKVTNEREAQQRIDQARNDALDAAARAGRLQQQLFAIREQ
                     LRQYNAIVGAGTSAADTGVLLADVLSKSLERNRQLAEYADRAAEAGRVCEKQYDTLTR
                     "
     gene            complement(1929..2558)
                     /locus_tag="IRB70_003012"
     CDS             complement(1929..2558)
                     /locus_tag="IRB70_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000403801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 19 protein"
                     /protein_id="HBC0632899.1"
                     /translation="MEIKQFQRAAGISEALAARWFSYITSAMREFGISKPEDQAMFIA
                     QVGHESGGFTRLQENFNYSVTGLANFVRAGRLTQGQANALGRRAGEPPLPLERQRAIA
                     NLVYSKRMGNNAPGDGWNYRGRGLIQITGLNNYRDCGNGLKVDLPENPELLAQDEYAA
                     RSAAWFFASKGCMKYTGDIARVTLIINGGRNGIDDRRARYVTASKVLAI"
     gene            complement(2548..2856)
                     /locus_tag="IRB70_003013"
     CDS             complement(2548..2856)
                     /locus_tag="IRB70_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBC0632900.1"
                     /translation="MATYELFFLITNAVICTGIAIRVVTFRRNGSQHRRWGGWLAYFL
                     IVAAASIPVRVAYAIWFRTPMAVDLSEVIINAVMLAAVIKTRGNVVQIFKVSRSKHGD
                     "
     gene            complement(2843..3247)
                     /locus_tag="IRB70_003014"
     CDS             complement(2843..3247)
                     /locus_tag="IRB70_003014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001272512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632901.1"
                     /translation="MSASLTADTINQGLSYGALAAVIAGVPPEVALGSLAGAVIFVTS
                     AVEYPIRRRVLLSMLSFLCGLLFYKPVASILIGIASLIPTITQDSFEKGVVFSAGAFV
                     SAIVAVRIGIWLYHRSDNPRELIPGRKDDGNV"
     gene            complement(5056..5523)
                     /locus_tag="IRB70_003015"
                     /pseudo
     CDS             complement(5056..5523)
                     /locus_tag="IRB70_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004207261.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
     gene            5719..5976
                     /locus_tag="IRB70_003016"
     CDS             5719..5976
                     /locus_tag="IRB70_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632902.1"
                     /translation="MQQYHYPLEDGFTERIHTPGGVRSLVEGSHLMKLLRDLDKDGFN
                     VDGPLAELTALINYVTSSQMSMQDLQTHLDYCAEQLRKQTR"
     gene            6158..6244
                     /locus_tag="IRB70_003017"
     CDS             6158..6244
                     /locus_tag="IRB70_003017"
                     /inference="COORDINATES: protein motif:HMM:NF022029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ash family protein"
                     /protein_id="HBC0632903.1"
                     /translation="MVGCVGAPKGAPGSFVAGKTNSAQFTTI"
     gene            6290..6982
                     /locus_tag="IRB70_003018"
     CDS             6290..6982
                     /locus_tag="IRB70_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001093358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRO-like protein"
                     /protein_id="HBC0632904.1"
                     /translation="MNTKPSIFSFESSCQIRMFMIDGEPWFVTKDVCNALNIDVTQAR
                     KLDKKGWNKKGLYSIQTPGGIQELSIVSESGLYILILRCKEAMTEGTRAFRFLEWVTG
                     EVLPQIRRTGSYIKNSLPQEERIKMVADQVANATASAVMQAMKIENKTYSAPLKPGYR
                     SLIHSPSGVLGLTENSLLMNLLNQLQDDGHDVSGAAAELTTMFCYIVGVSKCLRDIQT
                     HAEYINDKAGFF"
     gene            7104..7430
                     /locus_tag="IRB70_003019"
     CDS             7104..7430
                     /locus_tag="IRB70_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001609225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632905.1"
                     /translation="MSRRYVKELAIESGTPLGIVPGSNYAKALNRDSVVKVISRDMNM
                     VGDDLRRSENRVYAEYIVKNGKKIAAPAGGKWAIVTGKNSNARGKPEAKGMSFDKYAK
                     IYWATK"
     gene            7357..7905
                     /locus_tag="IRB70_003020"
     CDS             7357..7905
                     /locus_tag="IRB70_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001154801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2335 domain-containing protein"
                     /protein_id="HBC0632906.1"
                     /translation="MQEENQKLKECPSTNMQKSIGQPSDNEETEFEEVEEGLSNEIIQ
                     HPDAFTRVLDRPEIQEIVVAHHAFQGPLPPPYLLRGYQDILPDAPERIFQLTEKEFAH
                     RQKMEEKALDGAINRDKRGQWFGLSATIFTVACATLLGLTGHEVLAGTVIGTVVAVAG
                     IFVLRQKPSIKKKSEDNKPEEK"
     gene            7999..8160
                     /locus_tag="IRB70_003021"
     CDS             7999..8160
                     /locus_tag="IRB70_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000708858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transmembrane anchored protein"
                     /protein_id="HBC0632907.1"
                     /translation="MKKAFAALFVLLSLVASTQAFAGRCQHDSDTAADGSRCGGRSAD
                     SRPGGGGIR"
     gene            complement(8197..8757)
                     /locus_tag="IRB70_003022"
     CDS             complement(8197..8757)
                     /locus_tag="IRB70_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000643933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632908.1"
                     /translation="MKAIIFFVSILMSAFSFAGQNVKCELQYFGDSDKFKVTQFSFMG
                     IPSDSYLYTCADCGGIQINVFPSIQTVASYSFENNIDFERKINAEYNRKDIAKLEMEN
                     VTQGGRIKYSITDTGLAEFYPEGKKISYLYFLAKQQNGKEQVGYSGFVTSNGDKSCSI
                     IATYPGKEISFLGSKSLSYFMNHISM"
     gene            complement(8760..11309)
                     /locus_tag="IRB70_003023"
     CDS             complement(8760..11309)
                     /locus_tag="IRB70_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632909.1"
                     /translation="MAANEFLTQCERSVNAAAGRELSSDEMESLVRDMNDTTRRILAT
                     NEALSLEEAAMRAAEELSNADMLAKQIEARNKAINARIAAQRLRELRTIWKDRPDIGL
                     EAMLVGRNDARTGARRSVSSEVAQLRGKYHSGINYDFDRAGLVQFIASGSNDREIADA
                     MWRIGRGQSTDGMTKQSVSAAQIIMKWQETARIDENRAGAWIRKEPGYIVRQSHDIMK
                     IRAAGYEAWRNAILPRLDERTFDGVADREQFMRNIYNGLASGVHLTSEKPDWMNGFKG
                     SANAAKRASQERILHFKDGISWHEYNQQFGTGSLREALFGGLNSAARTTGMMRVLGTN
                     PQNMFKYLTDAIAEDISKSGRPAALADYMTKVRRINRTVMPQVDGSLNIPGSVGWANA
                     SAAVRGWLRMSQLGGAVISSFNDVPIAATEMRYQGQNFMQALLGAMRGRFTRYNSAEQ
                     KEILSSIGVYSDSMTQEIIRRISGDDTLNGKLGRAQQLFFKYNLMNFWTESGRNSNAM
                     MITNWLAKNADQSHARLPEDLRRVLDLHGIGEREWEIFRNMDMADSEGRKFMTTSGIR
                     GVPDEVIAGYVESKGIKPTQRAIADARDQLEGQLRGYILDRLNIAMSEPGDRTQAFMK
                     MGTVPGTVAGEAIRFAGQYKSFTASFMQNVLGREVFGRGYIPAGLGESKTGSLTNALL
                     RNGKGAFLGAANLFVWATMFGYISMQSKLMLKGQTPRPADAKTFLAAASQGGGLGILG
                     DFMFGEVNRMGAGPVTSLMGPAASNADSIITLLQQTTRGDADLGDWYRTALDNTPFLN
                     VFWLRTAMNGLILNRIQDALDPGSLERYQRRVEREQGNDFLIPPSQFMLGK"
     gene            complement(11309..13006)
                     /locus_tag="IRB70_003024"
     CDS             complement(11309..13006)
                     /locus_tag="IRB70_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632910.1"
                     /translation="MPIYTDDPGQGINQPIGNAPAGLGESLLSSLKQGFEEGPVMSGY
                     RFAQADSLANDPNSTVISKQEADELLKQYGVKSINVPDSGVTQAFLDHVIAERKDSLA
                     RQQIAMSAPSGWVATPLNFAASLAGSMADPGNVALALVPFAGEAKAASVLGRFGERFV
                     AGARMGAAQALVTVPLTGLAAAAEGDDFTYSNALESTFFNTMAGGLMHAGGGLIADIV
                     RPRRVPDAATGESPAFSGDAQPTPVITPDNIPAGVNIPEVGANADLAAAISSEAESYA
                     YSRAYDDVVPDYMARQQELQSGQIGNVADLRAELAANQRHADSLDATLQQRTKKYQGQ
                     RMKFKDARSRALKEIQAEKDAIAARNQEINTSLEQNATAEQARWRQSQISRGEIPDDL
                     KVTISERAQQILDGMQMSPVAGAVRTAASAIRDADWNVNQQAYRAALAHMMEGRSPDV
                     EPFYELHKPALRERAIHRIQNPARQVDETARPASETADRVYQETQKADHEITAAAADL
                     DNELNLSNALLDDIAVDNPDLATTLRQKLNDIRADASDNSMSNAFRAFAACMINRGM"
     gene            complement(13008..15629)
                     /locus_tag="IRB70_003025"
     CDS             complement(13008..15629)
                     /locus_tag="IRB70_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001145657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HBC0632911.1"
                     /translation="MPVVPTVSGRQVESRGVQSAGLQTFSQPGIGDAFVRAGTEAIDV
                     LGQAKQRANIALAQEASLNLSQISSDLLNNPETGLLNLKGKNAIGKGHEYTQQFDAQV
                     EQLAMSLPDEQARNAFMQQAQQQRIQFTTQAGRYEIGQVRQYEADMQDATLKNLSMQF
                     RNPTMANQAGLKAYHSIIAYGEAHGQSQEEIEQNWVSWRENAANGAAEAWYVPMYQQM
                     MGPNGKIEVTDTPSEAQLFSAIIWQESGGNQYGKDGTPLVSPKGAVGVAQVTEDTGPE
                     AARLAGVPWDRDKWLNDPRYNARLGQAYFGAQMKKYDNNPVLAVAAYNAGPGKVDGWI
                     KQIGDPRTGEVSNAQFAAAIPYDETRNYVAKVTGSAGVIPGSATMENLIAQPFWNAMS
                     PDKKSQMMSKVAGMYDMQASAGRVALQSRMQDDLSKIEAGKQVTPISAHEWAAVMPLQ
                     AAPAERLQMEKTFQQYQQAMTLQPVYQTIMQGNVQQGTAAVQAMAPQENDPDFKYKAE
                     LYASAKVKLGQVLKAREADPGAWLQQNSPVVQAAFQQYLNDPSSGEYLVSRIQSEKDR
                     LGIMSKKVLPESMVNDVLQRIDNTQESSVKAIQSVAQSFGKYSDQVMQQVQKSAYPAL
                     QVVMATENPRAANALWQNRSVKTADLRGSLEKTDADSADSSWNDQSKDFAGTMVVQPG
                     GTAVWNNFNEQGKRLTYINMQRGMSASDAAKQAYQDILGEQYQTNGTWRLPKRAGIDI
                     RDVNDGANAYLKNLSADQIMPLIGDPRLPDEVNREQSISRIRDNAQWVTNSDETGLTL
                     MLNGLIVNGADGNPITVPFNDLAKLGTTNRSVWNSITKFIDTPVKYTPGQSKEYSAES
                     QRDNLINIFQNGQQSGR"
     gene            complement(15629..16174)
                     /locus_tag="IRB70_003026"
     CDS             complement(15629..16174)
                     /locus_tag="IRB70_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632912.1"
                     /translation="MCDPVIAGGAMLAMSGIQAYTQYQQGKYASKVAEANADIATAQA
                     NDAINRGNAEAEQRRRETRQRLGTQAATMGATGADLSTGNALDIFGDTAQFGALDSLT
                     TVNNAQREAYGYQVQAANYKAEASSARKQGNVGAATTLLTAPLKAYGAYQMFGGTWSP
                     FTQSTPAPIGVAAGTRLPGGL"
     gene            complement(16174..16638)
                     /locus_tag="IRB70_003027"
     CDS             complement(16174..16638)
                     /locus_tag="IRB70_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632913.1"
                     /translation="MIDVQIIPATEEHLQMILPDVRQADIDELYAVSLMTTEDALRVG
                     LRTATMAWSGFANGELVTMFGVSPASMIGGNGTPWLVGTSRIEKYQKTFLRHCRPVLQ
                     QMLAVYPRLENYVDERNHVAKAWLHWLGFRLEEAAPYGALGLNFHRFHMERK"
     gene            complement(16638..19109)
                     /locus_tag="IRB70_003028"
     CDS             complement(16638..19109)
                     /locus_tag="IRB70_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632914.1"
                     /translation="MAISWIQPSFAGGEIGPSLYGRIDMAKYQVALRKCDNFIVRQYG
                     GVENRPGTRFVGAAKYPNRKCRLIPFQFSTVQTYALEFGHQYMRVIKDGALVLNSSNV
                     IYEIATPYTEADLFRIKFTQSADVLTLVHPAYPPKELRRYAHDNWQLVDVVTKNGPFE
                     DINIDESVTVYASASTGTITLTASASIFGAEQVGKLFYLEQPAVDSVPVWETSKSTSI
                     GDIRRADSNYYRAVTVGKTGTLRPSHTEGTSWDGWGGSGDDDTGIEWEYLHSGFGIAR
                     ISAANGTTATAEVISYIPSQVVGEDNASYKWAKYAWNSVNGYPGTVVYYQQRLYFAAS
                     TAFPQTIWASRTGDYKDFGKSNPTQDDDRIIYTYAGRQVNEIRHLIDVGSLVALTSGG
                     EYVITGDQNKVLTPSSFAFSSQGSNGSSNVPPIAVANIALFVQEKGSVVRDLAYSFDV
                     DGYQGNDLTILANHLFQKHSIVDWCFSIVPYSSAFCIRDDGKLLVMTYLRDQQVFAWA
                     PQSSTGKYESTCSISEGNEDAVYFVVNRTVNGQTVRYIERLSSRLFTSDEDAFFVDSG
                     LSYDGRNTSDRTMIITGGSGEWDYREEYTISVSGGAYFTSSDVGAQLQFPYTGTDPDT
                     GDEVSKELRCDIISVTSNTAVVVRANRNVPPSLRNVATTNWQMARRTFGGLSHLEGQT
                     VNILSDANVEPQKVVSGGAVTLESPGAVVHIGLPITAEFETLDININGQETLLDKKQV
                     IPSVTLVVNASRGIWATTPGGKWYEYPQREFEFYDDPVDDATGKVEVKLDSNWGKNGR
                     VKIRQLDPLPLSVLAVIPRLTVGGF"
     gene            complement(19109..19714)
                     /locus_tag="IRB70_003029"
     CDS             complement(19109..19714)
                     /locus_tag="IRB70_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632915.1"
                     /translation="MASVVEICNRALSNIGNSRSINSLTEASKEAGECSLHFEACRDA
                     VLSDFDWNFATKRVALADTSNPPPDWEYAYQYPSDCLRITEIMLPGVRNPAAPMRVQY
                     EVGADTNGTGKLIYTDQPQAWLKYVSRVTDVNMFDAIFMEALAWRLAAAINMALTGNA
                     DLGTFALNMYNRVILSAGSHSQNESQEPQPPIDEFTIARLS"
     gene            complement(19714..20037)
                     /locus_tag="IRB70_003030"
     CDS             complement(19714..20037)
                     /locus_tag="IRB70_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632916.1"
                     /translation="MELVNLKTGTDSYQDESGETRTRDEYPWGLCITLNNDTLNKLKA
                     QPQGVGTEVMITAKAVIRGLSARETDDGVNRSAELQITDMAIAPVSGDVEKSAAETLY
                     GNGGE"
     gene            complement(20088..20423)
                     /locus_tag="IRB70_003031"
     CDS             complement(20088..20423)
                     /locus_tag="IRB70_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000012377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632917.1"
                     /translation="MSGEKPRYRVLRLSHIHNTLWPEGAEIEYEGEPGSALEPVNDAA
                     RQAKAKVAGKVSMAATSTKIINDVSDDGELDKLREEYELLFNEKPHHNAKAETLREKI
                     ADKRKELGV"
     gene            complement(20434..20871)
                     /locus_tag="IRB70_003032"
     CDS             complement(20434..20871)
                     /locus_tag="IRB70_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632918.1"
                     /translation="MITDKLLMFSEAQAVTDTAASTDVIDLGPIDGNRRDIGVGYPLE
                     FWALVNEAATASGEATVNIQLQTSENNSSWSTIYDSGALAKATLTAGKRVVSAKVPAG
                     VQRYLRVNYSVATGPLTAGKFTAGISLDVDANTPYPIRSKVTG"
     gene            complement(20923..21909)
                     /locus_tag="IRB70_003033"
     CDS             complement(20923..21909)
                     /locus_tag="IRB70_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000268714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632919.1"
                     /translation="MSVKGLTALTLADWGKRVDPNGKVDKIIELLGQTNPILQDMPFV
                     EGNLPTGHRTTIRSGLPSATWRLLNYGVQPSKSTTVQVTDSVGMLETYAEVDKSLADL
                     NGNTAEFRLSEDRAFIEAMNQQMAQTLFYGDSSVNPQQFMGLSSRYSSLSAGNAQNII
                     DAGGTGTDNTSIWLVVWGENTVHGIFPKGQKAGIQMEDKGQVTLEDADGGKYEGYRTH
                     YKWDNGLALRDWRYVVRIANIDVSNLSEPSSAANIAKLMVKALHRIPNRGMGRPVFYM
                     NRTVGQALDLQSLEKTSLAISVKETEGEWWTSFRGVPIRETDALLETEARVV"
     gene            complement(21924..22619)
                     /locus_tag="IRB70_003034"
     CDS             complement(21924..22619)
                     /locus_tag="IRB70_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001048067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBC0632920.1"
                     /translation="MNLFERLLYRRLCNEQPVDGGAAPAASEPSAPAGDNPAPVGDPS
                     QQEGDKPQPVADGDKPADDKKPENDKQDEKKDGDKPEGAPEKYEFQAAEGVELDTEAL
                     KEFEPVARELNLTNEQAQKLVDAYPKILAGVQQRQAEAWQKTTEQWAADVKADKEIGG
                     DKLISNLSAAQRALDQFGTPELKEYLNTTGLGNHPDLVKTFVKIGKAMSEDGMVTGGN
                     EGQRSAAEVLYGK"
     gene            complement(22622..22918)
                     /locus_tag="IRB70_003035"
     CDS             complement(22622..22918)
                     /locus_tag="IRB70_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632921.1"
                     /translation="MTDYEDDQLKEENARKQRDMAQREIDDIRFVMSSEQGRRVVWSV
                     LEKGRVFSAISPMDAMAMAFNEGQRNLALELFQRVMAHCPEQYLKMAKEASEQE"
     gene            complement(22915..24594)
                     /locus_tag="IRB70_003036"
     CDS             complement(22915..24594)
                     /locus_tag="IRB70_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016245492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0632922.1"
                     /translation="MAETTKERLNKQFAQLESERQSFEPHWRELSDYINPRGSRFLTS
                     EVNRNDRRNTRIIDSTGTMAARTLASGMMSGITSPARPWFRLATPDPEMMDYGPVKLW
                     LEAVQNRMNDMFNKSNLYQSLPQLYGSLGTYSTGAMAVLEDDEDIIRTMPFPIGSYYL
                     ANSPRGSVDTCFRKFSMTVRQLVQEFGLNNVSESVKSMWESGTYEKWIEVMHSVYPNI
                     DRDTSKLDSKNKPFKSVYYEVGGDNDKLLRESGFDEFPIMAPRWEVNGEDVYGSSCPG
                     MLALGPVKALQLLQKRKSQLIDKATNPPMVAPTSLKNQRASLLPGDITYIDQITGQDG
                     FRPAYLVNPSTADLVADIQDTRQIINSAYFVDLFMMLQNINTRSMPVEAVIEMKEEKL
                     LMLGPVLERLNDECLNPLIDRAFSMMVRKNMLPPPPDAMEGMPLKVEYISVMAQAQKS
                     IGLSSLASTVNFIGQLAQAKPEALDKLNVDQAIDAFADMSGVSPTVIVPQEQVEQARQ
                     QRAQQQQQQQMMAMGMAAAQGAKTLSEAKTSDPSVLSAMANAVSGQGGQSQ"
     gene            complement(24609..24815)
                     /locus_tag="IRB70_003037"
     CDS             complement(24609..24815)
                     /locus_tag="IRB70_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632923.1"
                     /translation="MCIGSSPSVPATPEVQAAPQEQDAAVVDARDEETRRRRAAAGRS
                     STLLTGSQGDTSTANTSGKTLLGQ"
     gene            25244..25320
                     /locus_tag="IRB70_003038"
     tRNA            25244..25320
                     /locus_tag="IRB70_003038"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:25278..25280,aa:Arg,seq:tct)
     gene            25518..25889
                     /locus_tag="IRB70_003039"
     CDS             25518..25889
                     /locus_tag="IRB70_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001595512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632924.1"
                     /translation="MNDQQIEKEIIEKGKTAPRVTPDHIEGIIAQEAYFTAEDGAFGK
                     AIKAKHTGGEVNYQPHESLSLLTFCVLVLRNGFTVTGESACASPENFDAEIGRKIARQ
                     NAVNKIWMLEGYLLKQKLSEQ"
     gene            complement(25980..27455)
                     /locus_tag="IRB70_003040"
     CDS             complement(25980..27455)
                     /locus_tag="IRB70_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016236153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase"
                     /protein_id="HBC0632925.1"
                     /translation="MTDTALSPEEQLIEDIAVFTHDPLGYALYAFPWGEEGTELAHAT
                     GPRQWQADAFREIRDHLQNPETRYQPLMLARASGHGIGKSAFISMLINWGMSTCEDCK
                     VVVTANTDNQLRTKTWPEIIKWSNLAITKDWFTCTATAMYSNDPGHDKLWRADAIPWS
                     EHNTEAFAGLHNERKRIIVVFDEASNIADLVWEVAEGALTDEDTEIIWVAFGNPTRNT
                     GRFRECFRKYKHRWKCAQIDSRTVEGTNKQQLQKWVDDYGEDSDFVKIRVRGIFPDAS
                     ELQFIPTGLTDEAMKRVVTAAQVAHAPVIIGVDPAYSGVDDAVIYLRQGLHSKVLWTG
                     NKTTDDLIMAKRIADFEDLYQADAVFIDFGYGTGLKSIGDGWGRTWQLVPFGGASTDP
                     QMLNKRGEMFNACKTWLRLGGMLDDQETADDLSAAEYKVRVDGKIVIEPKEDIKERLG
                     RSPGKGDALLLTFAFPVSKRLRIPGQQNQQGKAITDYDPYA"
     gene            complement(27452..28162)
                     /locus_tag="IRB70_003041"
     CDS             complement(27452..28162)
                     /locus_tag="IRB70_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBC0632926.1"
                     /translation="MNTAANYGGFILHGTITTTVTITMVVMMPAEPKTYKRKSTQFKP
                     LTSMQEAYCQSYIKTPENQTQAAINAGFSPNTAAVKASVMMRDERIQKRIAELMEERN
                     KRMRVSADYVLMRLVEIDQMDVLDILNDDGGMKPIAEWPKVWRTSLSAMDIATIKTTQ
                     ASLQKENGEADLSVEDVEHILKKVKWPDKVKNLELIGKHVDVNAFKERLDVNVNVTIA
                     DRIAAARKRLKERQDGNQ"
     gene            complement(28203..28541)
                     /locus_tag="IRB70_003042"
     CDS             complement(28203..28541)
                     /locus_tag="IRB70_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632927.1"
                     /translation="MAKSAAERKAAQRARQAASGVRKLEIVLDAQEIQMLERNCATRR
                     PGRAPYEFGEYIALLIRQDDARVRGRIKSISRKRCGKCGERVPVNSCPCNGDSQCWVT
                     KGWHETKLIV"
     gene            complement(28534..28917)
                     /locus_tag="IRB70_003043"
     CDS             complement(28534..28917)
                     /locus_tag="IRB70_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2591 family protein"
                     /protein_id="HBC0632928.1"
                     /translation="MDYSQLSDFEINVAVFEAIHNGSPDYKEGENGDMVFVSFEGDIV
                     NGDAVEVEVERGSFNPCANPADAWPIITENNISIILDNPSMPCATDNARDLFDDAGPN
                     VGVAYDNPLRAAMIVFLMMQENQNG"
     gene            complement(28917..29519)
                     /locus_tag="IRB70_003044"
     CDS             complement(28917..29519)
                     /locus_tag="IRB70_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001749404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF551 domain-containing protein"
                     /protein_id="HBC0632929.1"
                     /translation="MAPQLTQPAPVSVPDEIPKLKDGMGFKYVKDGVRYSLNYANGWN
                     QCRAAMLQAEPVSNSDELPLDYLQGHKDGLEWAAQLAEANHPQTGDWLYDDPIDLAKA
                     IRKGPDMPTVQGGNSPVTPDGWISCSERMPEMGERQCYVLAADFKNNYPPNIPNTQVG
                     VYGDWFNDGNPTWDDGGGEDLYLKEVTHWMPLPEPPQEVK"
     gene            complement(29850..30299)
                     /locus_tag="IRB70_003045"
                     /pseudo
     CDS             complement(29850..30299)
                     /locus_tag="IRB70_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000405097.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(30361..30663)
                     /locus_tag="IRB70_003046"
     CDS             complement(30361..30663)
                     /locus_tag="IRB70_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632930.1"
                     /translation="MNKTESAYCQHLELRKRAGEIAWYRFEGIKLRLANNTFYTPDFA
                     VMLATGEMELHEVKGGFWTDDARVKTKVAADQYPFRIIGVTVKPKKAGGGWNIEEF"
BASE COUNT         7340 a         8191 c         7299 g         7846 t
ORIGIN      
        1 aaaattaata catatgtttt aatgatgtat ttttataaat tattttccac atgaatttta
       61 ataaatttaa tctattcctt tatacgcaat acatttactt tcctcttttg atgatcttaa
      121 atgtcttatt tttcgtaatg tgtataacaa ggaatagtga tgaaatttaa aaaatgtctt
      181 ctgcctgtgg caatgttagc gtcattcact ctggcaggat gccagtcaaa tgctgatgat
      241 catgccgccg atgtttatca aaccgatcaa ctgaatacca aacaagaaac taaaaccgtt
      301 aatattattt ccattcttcc cgcaaaagtt gccgtagaca actcccaaaa taaacgaaac
      361 gcacaagcct tcggcgcgct tattggtgca gtcgctggcg gtgtaatcgg ccacaacgtg
      421 gggtctggca gcaattccgg aacgacggca ggtgcagttg gcggcggagc tgttggcgcg
      481 gcagcgggtt ctatggtgaa tgataaaacc ttagtggaag gtgtttctct aacgtataag
      541 gaaggcacca aagtgtatac ctccacccag gtgggtaaag agtgccagtt tacgacaggt
      601 ttagccgttg ttattaccac gacgtataac gaaacgcgta ttcagccaaa taccaaatgt
      661 cctgaaaaga gctaataatc aggaggagtc atgaagaaag tttttctttg cgccatctta
      721 gcctccttta gctatccggc tatcgcctca tcattgcagg atcaactctc ggctgtcgca
      781 gaagcggaac agcaaggtaa aaatgaagag caaaggcagc atgacgaatg ggtcgcggag
      841 cgcaacaggg aaatccagca agagaagcaa cgtcgcgcaa acgcccaggc cgcggctaat
      901 aaaagagcgg caacggcagc ggcaaataag aaagctcgtc aggataaact ggacgccgaa
      961 gccactgcgg acaaaaaacg cgatcaaagt tatgaagatg agctacgcag cttagagatt
     1021 cagaaacaaa aactggcact ggcgaaagaa gaagcccgcg ttaagcgcga aaacgaattt
     1081 atcgatcagg aactgaagca caaagctgcg caaaccgatg tggtgcaatc tgaagctgac
     1141 gcaaacagaa atatgactga aggcggtcgc gatctgatga aaagcgtggg caaagcagaa
     1201 gagaacaaat cggacagctg gtttaattaa tcgatgtaag taacttcaag cctataattc
     1261 ttgaagataa aaaaccctct gtagtaacag agggttttgt tcattcatag tgcagggatc
     1321 aaaatcattc ccactcaatt atttacgata accataacca attgagtgat aacatttttc
     1381 caaatctcaa tttttcccgt accgttttat ataccgtcac cggaaatcag taccatgaaa
     1441 aatgccatgc tatctggtca aagtgtcata ctgtttttcg cagactcttc cggcttcggc
     1501 tgcccggtca gcatactctg ccagttgtct gtttctctcg agagatttgc tgagcacgtc
     1561 ggcaagcaaa actccggtgt ctgcggctga cgtcccagcg ccgacaatgg cgttatactg
     1621 cctgagctgc tcacggatgg caaagagttg ttgctgcaac ctgccagcgc gagcggcagc
     1681 atcaagagca tcattgcgcg cctggtcgat tctctgctgc gcttcacgtt cattggtcac
     1741 tttctcctgt tcgtagtact gacgaacttt gtcttcttcg tctttgcggt cttcttccgc
     1801 ctgcgcatac ccggcatcgt actggcgact gccgtgtata ttccaggcaa ccactccgac
     1861 gatgaacaga gcagcaagca tcaccacgat aagtagttgt ttccaatatg cttttacgaa
     1921 tgcccagatc atatagccag caccttactg gcagtgacgt accgcgcgcg ccggtcgtcg
     1981 atgccgttcc ggccaccatt gataatcaga gttacacgtg caatatcacc ggtatacttc
     2041 atgcatcctt tgctggcaaa gaaccacgcc gcgctacgag ccgcgtattc gtcctgcgcc
     2101 aacagttcag gattctccgg caggtccact ttcaggccgt ttccgcaatc acgatagtta
     2161 ttcaaaccgg taatctggat aagtccgcga cctcggtaat tccagccatc gccgggggca
     2221 ttgttcccca tgcgtttgct gtacaccaga tttgcgatcg cacgctggcg ctcgagtggt
     2281 aatggcggtt caccagcacg gcgacccagt gcgttggcct gtccctgagt gagacgaccg
     2341 gcacgaacga agttagccag tccggtgacg ctgtaattga aattctcctg caacctggtg
     2401 aagcctccag actcatgccc gacctgagca ataaacatag cctgatcttc tggtttgctg
     2461 ataccaaact ctctcatcgc agaagttata tacgagaacc agcgtgcagc cagcgcctcg
     2521 ctgataccag cagctcgctg gaattgttta atctccatgt ttagacctcg atactttgaa
     2581 aatttgaacg acgttaccgc gcgttttaat aaccgcagcg agcatgacag cgttgataat
     2641 gacctcagat aaatccacag ccattggcgt gcggaaccag attgcatagg caacacgaac
     2701 cggaatactg gccgcagcaa caatcaggaa ataagcaagc cacccccccc atcttcgatg
     2761 ttgagatccg ttacgccgga atgtgacaac gcgaattgct atgccagtac aaataactgc
     2821 attggtgata agaaaaaaaa gctcatacgt tgccatcgtc ttttctcccc ggaattaact
     2881 cacgtggatt atcggaacgg tgatagagcc agatgccaat tcgtactgcg acgattgctg
     2941 acacgaatgc gccagcagag aaaacaaccc ctttctcgaa agagtcctgg gtgatggtag
     3001 ggatcaggct agctatgcct ataagaattg atgctactgg tttgtagaag agaaggccgc
     3061 agaggaagct gagcatcgat agaagaacac gacgacgtat tggatactct accgcagagg
     3121 taacaaaaat taccgcacca gccagcgatc caagcgcgac ttcaggaggt acgccggcga
     3181 taactgccgc cagcgcaccg tagctaagcc cctgatttat tgtatcagcg gttagcgatg
     3241 cggacatgat gaccaccgtt tactatgcat gatgaacctc cttagttggg taggttcatc
     3301 atacacaatt actcaaatat gaataaatgg taatagtcat taatggatga aagaataggg
     3361 attagcaatt gtgtattgcg catttgtccc tattggagta tcaaaaatcc acacttcact
     3421 tagtccatcc ttagtaattg tcgcattcgg accgctatgt ttacagccat atagatatac
     3481 ctttgcttta ccagttaaat cagatccttg tccagcagta aagcaggcgc caccgataaa
     3541 gtctgccctc gagctgtcat gcgagtaaca cccaaagtta gctgtaaccg tgccatcatg
     3601 aacatcgtga actacacggc caaacgttcc gtagtattca ccgttcaaac gtatccctac
     3661 agttccgtca tgagcggtag agccgttatt atttggtaaa ttatcaaaac cactccaacg
     3721 gccagtacaa ccaatttcga taaaccacgg ctttatccca agaccattct gatcggcatg
     3781 atagttaaat gcgtcctgca tcccgtattg agcagtgcaa ttctgcataa tacagtttac
     3841 acctaaagag ttaaaggcat tccttgtcac agataaatca aatatacaat tttttgcata
     3901 taagtatcct tttttaccca ccgtttgaac ctcagcctga aaacccctaa agctgtcctt
     3961 aaagtgaata ttttcaatat aaactttgct attatcctga attcttccat tagtcaattg
     4021 aagaacaagc cgtgaattag aatcaggcgc tcgcccgtca aaaagatgaa tatacagcgt
     4081 attccctgtt ttataggatg agccaggtgt tgaaacgcag tcggcaaggc tggctacggg
     4141 agttagaacc tgagcatgtc cataactatc aagattggca tagtcaacaa cgtttagaac
     4201 aagattacct gtgtactggt atacgccagc gcttccctgt gccgcccacg ttgcaaccgg
     4261 ttcaacagtg ctcagaattg gtgttccatc gtatccgatg aaatcgagct cgcggtcaac
     4321 tacgctaaca ttccatgtaa aatcacgggt atattccatc ccgcctttta tcatgattgt
     4381 ccttgctgcc ggggttttct caatggcata ttttatacgc tggaatggtt tagcctgcgt
     4441 gccgtctcca gtcgtatcac taccgttagt gcagtccaca taatatgttg tcccgctgga
     4501 tgccttcttc acagccacat cataatcagt ccaatatcta agcgtgccat cagaacgaag
     4561 tgcgcagtaa attggaatct gctcttctat tcttctcagc tcacctggaa accatggtat
     4621 tgatgagggg catccggcaa ttccaaaagc acttttattt gcattgccaa ttaattctac
     4681 aagagtccct gatttaatat gagcaataag tagcgagccg tcaaatggat atctgtcacg
     4741 cgcttcatat gttccgtctg atttaacaac aatacatatt gtgcttgatg ttgttgtgac
     4801 attctgattt tgaccaataa cactaacgcc attaaaagaa taaagaccgc cagaaaagct
     4861 tatagttgat gatcctgcaa ctggtttcca ttgaggagat gtaatgaccc ctcctaacga
     4921 tctgtataat ctatcaagag ccgtataaac ggtgctgtcc ctatagccta caatgcctgc
     4981 accgtcagga gcagcaagat cagcccgaag agttccttcg atggcgccac ctgcaagagc
     5041 ttccacccat tgcgcggttg ctgcatctga cccgtatttt gggtcttgta agttgcttat
     5101 cctgttgttt tttgcatcat agtatgaggc catcaacgat ggcttaagaa gcgctaaacc
     5161 caactctgca aagcactgtt ggattagcat agttaatttg tcaaaagcat cttcgtgcac
     5221 ttcagcaaaa aatttaccct ggtttctcag gtctgtttcc tgcgttgcag gcaagtccct
     5281 ggctattaat atctgccaac catttttcag cggagaaggc aaaaccactg ttccgcctga
     5341 gtatatccca gcaccagtaa cgctatagtc ggaatcaaga gtcagaacgg taatgttctc
     5401 atccacatca gctatctgaa ctttcagatc tgacggcttg aaaatcctga aagtatacgg
     5461 gaacgatgtg gttacgccgt taccggtgta ttcgttgtgg tcaacttcgg ttgataccgt
     5521 catgttaaat ctccagatag tcgcagcacc cgttgcgccg catatccggt tattttatta
     5581 cctgaaaaac catatatgga tagaaaggct gtaaatacga atagatatta cctttcaggt
     5641 gattggcaaa acgtgctgga tagcaaacaa attatttgat actgtataaa tatacagtta
     5701 ttgcatggag aagataagat gcagcagtat cactatccac tggaagacgg atttaccgaa
     5761 aggattcaca cgccgggagg cgtcaggtca ctggtggagg gatcgcactt gatgaaatta
     5821 ctccgggatc tcgataagga tggatttaat gtcgatggcc cacttgccga actgactgca
     5881 ctgattaact acgtcaccag ctcacagatg tctatgcagg atctgcaaac acatctcgac
     5941 tattgtgccg aacaattacg aaaacaaacc agataaggtt tgcaattacc aaatggagtg
     6001 cttatattta cctttgcggt aaatttacat cgcactcctc ttgtgccata gtaatcgggc
     6061 actggcaaaa tccagtgccg ggattggtct cccggattac tacagaggca catatgccgc
     6121 ataagcggtt tttttatgtg taaagcgcac ctattctatg gtgggctgtg tgggggcacc
     6181 gaaaggtgcg ccgggttcct ttgtagccgg taagaccaac tctgcacagt tcaccaccat
     6241 ctgattggtc tcagcggtgg tgattaacct aactacaaag gtgatcgcca tgaataccaa
     6301 accttccatc ttttcctttg agtcatcctg ccagatccgt atgttcatga ttgacggaga
     6361 accttggttt gtcaccaaag atgtgtgcaa tgctttgaat attgatgtta cacaagcgag
     6421 aaaacttgat aaaaaaggct ggaacaaaaa ggggctgtat tcaatacaga cccctggtgg
     6481 aatacaagaa ctatccatcg tttcagaatc aggtctctac atccttattc tgcgttgcaa
     6541 agaggcaatg actgagggaa cgagagcatt cagatttctt gaatgggtta caggtgaggt
     6601 tcttcctcag atccgccgca ccggaagtta cattaaaaac tcgctcccgc aggaagaacg
     6661 cataaagatg gttgccgacc aggtagccaa cgccacggcg tcagcagtga tgcaggcaat
     6721 gaagatagag aacaaaacct acagcgcccc actgaagccc ggctaccgca gcctgattca
     6781 ctcgccgtct ggtgttctcg gcctgacgga gaactcactg ctgatgaatc tgctgaacca
     6841 gttacaggac gacgggcacg atgtatcggg cgcggcggcg gagctgacca ccatgttctg
     6901 ctacatcgtc ggtgtgagca aatgcctgcg tgatatccag acgcacgcgg agtacatcaa
     6961 cgacaaagca gggttcttct gacgggcggc ggcacaggga tgtgcctaca attatcaata
     7021 attgtttaca ctcgttgcag ttaaaagcat tatactcatg tttaaaatta cccgattggt
     7081 aaagtcgatt ggttgaggtt catatgagca gaagatatgt caaggagctg gctatagagt
     7141 ctggcacccc tttgggtatc gttcctggct ccaactatgc caaggcttta aaccgagact
     7201 ctgtcgtcaa agttatatca agagacatga atatggtcgg agacgatctc agacggtcag
     7261 aaaatcgtgt ttatgctgaa tatatagtaa agaacggaaa aaaaattgca gcgcctgctg
     7321 gcggaaaatg ggcaatagtg acagggaaaa actcaaatgc aagaggaaaa ccagaagcta
     7381 aaggaatgtc cttcgacaaa tatgcaaaaa tctattgggc aaccaagtga taacgaagaa
     7441 actgagttcg aggaagttga ggaagggcta agtaacgaga tcattcaaca cccagatgcc
     7501 ttcacaagag ttcttgatcg ccctgaaatt caggagatag ttgtcgctca ccatgcgttt
     7561 cagggtccgc ttcctccccc ctatctgctt cgcgggtatc aggatatttt acctgatgcc
     7621 cccgaacgca tcttccagct gacggagaag gagtttgctc accgccagaa aatggaggaa
     7681 aaggcacttg acggggctat taatagagat aaacgtgggc agtggtttgg cctgagtgca
     7741 actattttta cagtagcttg tgcaacatta ttaggtttaa caggtcatga agttctagct
     7801 ggcacagtga tcggtacagt tgttgcagtg gctggtattt tcgttcttag acaaaaacca
     7861 agcatcaaga agaaatctga agacaacaaa cctgaagaaa agtaagcccg cgctgcgggc
     7921 ttttttgtgg acgaaacaaa agtcagtgct acactcattg acgccacatt gaggtggctt
     7981 atagatggaa atgtcacaat gaaaaaagca tttgctgcac tgttcgtttt gttgtctctg
     8041 gtagcttcaa ctcaggcctt tgccggtcgt tgtcagcacg acagcgacac tgctgctgac
     8101 ggctcccgct gcggtgggcg ttctgcggat tcccgcccgg gtggcggtgg cattcgttaa
     8161 aaacaaggcc gcgaaagcgg cctgtgacat gtcacgctac attgatatat gattcataaa
     8221 gtagcttaaa gatttacttc ccagaaaaga aatttctttt cctggatatg tcgcaataat
     8281 tgagcatgac ttatccccgt tagaggtaac aaatcctgaa taacctactt gttctttacc
     8341 attttgttgc ttggctaaaa agtagaggta gcttatcttt ttgccctctg ggtaaaactc
     8401 tgccaaacca gtatcggtga ttgaatattt tattctcccg ccttgagtaa cgttttccat
     8461 ctcaagttta gctatgtctt ttctgttgta ttcagcattg attttccttt cgaaatcaat
     8521 gttgttttca aatgagtagg aagcaacagt ctgaatagat gggaacacgt ttatctggat
     8581 gcccccacag tcggcacagg tataaaggta tgaatcagat ggaatcccca taaaagaaaa
     8641 ctgagttacc ttaaatttat cgctatctcc aaagtattga agttcgcatt taacattttg
     8701 ccctgcaaaa gaaaatgcag acatcaatat tgaaacaaaa aatataattg ccttcattat
     8761 tatttaccta gcatgaactg cgatggtggg atcagaaagt cgttcccctg ctcacgctca
     8821 acacggcgct gataacgctc aagagagcct gggtcaaggg catcttgtat ccggttcaat
     8881 attaaaccat tcatcgccgt acgaagccag aacacgttga ggaatggcgt attgtcaagt
     8941 gccgtgcgat accagtcacc caaatctgca tcccctctcg tggtctgctg gagcagcgtg
     9001 ataatgctgt cagcgttcga tgctgctggc cccattagcg acgtaaccgg cccggccccc
     9061 atgcggttga cctcaccaaa catgaagtca cccaagatgc caagaccgcc cccctgagat
     9121 gcggctgcga gaaacgtctt ggcatctgcc gggcgtggtg tttgcccttt cagcatgagt
     9181 tttgactgca tggagatata accaaacata gtcgcccaga caaagaggtt tgcagcacca
     9241 aggaaagccc ccttcccgtt acgtagcagc gcattcgtca gcgatccggt tttcgactca
     9301 ccaagcccag caggaatata accacgcccg aatacttcgc gtcctagtac gttctgcatg
     9361 aagcttgcag tgaacgattt gtactgacca gcgaatcgta ttgcttcccc agccaccgtt
     9421 cctggcaccg tgcccatctt cataaacgcc tgcgtgcgat cgccaggctc tgacatggcg
     9481 atattcagac ggtcaaggat gtagccgcgc aactgccctt ccaattgatc gcgtgcgtca
     9541 gcgatagcgc gctgcgttgg tttgatcccc ttactctcta cataaccggc aatcacttcg
     9601 tcaggcacgc cgcggatgcc gctggtcgtc atgaacttac gaccttcgct atcggccatg
     9661 tccatgttgc gaaaaatttc ccactcacgt tcgccaatac cgtgcagatc cagcacgcgt
     9721 cgcaggtctt ccggtagccg cgcatgagac tggtcagcat tctttgcaag ccagttggtt
     9781 atcatcatgg cgttgctgtt gcgaccgctc tcggtccaga agttcatgag gttgtactta
     9841 aagaaaagct gctgcgcgcg accaagcttt ccattcagcg tgtcatcacc agatatgcgc
     9901 cggatgattt cctgcgtcat ggagtcggaa taaactccga tagaggaaag gatctctttc
     9961 tgctccgcgc tgttgtaacg cgtgaagcgg cctctcatag caccaagcaa cgcctgcata
    10021 aaattctgcc cttggtagcg catctcggta gcggcgatag gcacgtcgtt aaacgatgag
    10081 attaccgcgc caccaagttg gctcatacgc aaccagccgc gtacagccgc cgacgcattg
    10141 gcccagccta cgctgccagg aatatttagc gagccgtcaa cctgcggcat tacggtacgg
    10201 ttaatgcgac gcaccttcgt catgtagtca gccaacgctg ccggtcttcc ggatttgctg
    10261 atatcttcag caatggcgtc cgtcaggtac ttaaacatgt tctgtgggtt agtgcccagt
    10321 acgcgcatca tgcccgttgt gcgggcagcg ctgtttaagc caccaaacag cgcttctcgc
    10381 aggctgccgg tgccgaattg ctggttgtac tcatgccacg agataccatc tttgaagtgc
    10441 aaaattcgct cttggctggc gcgtttagct gcgttcgccg atcccttaaa gccattcatc
    10501 caatcgggct tttcagatgt aagatgcacg ccggaagcca gcccgttata aatgttacgc
    10561 atgaactgct cgcggtcagc cacgccgtca aaagtgcgct catcaaggcg cgggagaata
    10621 gcatttcgcc atgcttcata acctgcggcg cggatcttca tgatgtcgtg tgactggcgc
    10681 actatatagc ccggctcttt gcgtatccat gccccggcgc ggttctcatc aatgcgcgca
    10741 gtttcctgcc atttcatgat gatttgtgca gcgcttacgg attgctttgt cataccgtca
    10801 gttgactgcc cgcgccctat gcgccacatt gcatcggcaa tttcccggtc attgctgccg
    10861 ctggcgatga attgcaccag cccggcacgg tcaaaatcgt agttgatacc ggaatgatac
    10921 ttgccgcgca gttgcgccac ctccgaagat accgaccggc gggcgccggt acgcgcatcg
    10981 ttgcggccaa ccagcattgc ttcaagcccg atatccgggc ggtctttcca gatagtacga
    11041 agctctctaa gtcgttgtgc ggcaatacgg gcgttgattg ccttattgcg agcctcaatc
    11101 tgttttgcca gcatatcggc attgctcagt tcttccgctg cgcgcatcgc ggcctcttcc
    11161 agagacagcg cctcattggt cgccagaatt cgcctagtgg tgtcgttcat gtcacgcacc
    11221 agcgactcca tctcatcgga agaaagctcg cgaccagcgg cagcatttac actgcgctcg
    11281 cactgcgtca aaaattcgtt tgctgccatc acatcccccg gttaatcata caggcggcaa
    11341 atgcccggaa agcgttgctc atgctattgt cgctggcgtc ggcacgaata tcattgagtt
    11401 tctggcgcaa cgtggtcgca agatcagggt tatcgacagc gatatcgtca agcagggcgt
    11461 tactcaggtt gagctcgtta tcaaggtctg cagcggcagc ggtaatttca tgatctgcct
    11521 tttgcgtttc ttgataaacc cgatcggctg tttcgcttgc tgggcgagcc gtttcatcaa
    11581 cctgccgtgc cgggttctgt atgcgatgga tggcgcgttc acgcagtgct ggtttgtgca
    11641 gttcatagaa gggctcaaca tctgggctac gtccttccat catgtgtgcc agcgcagcgc
    11701 gatacgcctg ctggttcacg ttccagtcag catccctgat ggcgcttgcg gcagtgcgaa
    11761 ctgcgccagc gaccggcgac atctgcatgc cgtccaggat ctgctgcgca cgctcggaaa
    11821 tggtgacttt caggtcgtcg gggatctcgc cgcgggaaat ctgagactgg cgccagcgcg
    11881 cctgctctgc tgtcgcgttc tgctccagcg atgtgttgat ctcctgattg cgtgcagcga
    11941 tggcgtcttt ctcggcctga atctctttca gtgccctaga gcgcgcatcc ttaaacttca
    12001 tccgctgccc ctgatacttt ttggtgcgct gctgcagcgt cgcatcaagc gagtcagcat
    12061 gacgttgatt agccgcaagc tcggcacgca ggtcggcaac gttaccgatc tgcccgctct
    12121 gtaactcctg ctggcgcgcc atatagtcag gaaccacgtc gtcataagcc cggctgtatg
    12181 cgtagctctc cgcttcactg gaaattgccg ccgccagatc tgcgttagcg ccaacctcag
    12241 ggatattcac gcccgccgga atgttgtcag gcgttatcac cggggttggc tgcgcatcgc
    12301 cagaaaacgc cggggactct cccgttgcag catcgggaac gcgacgcggt cgcacgatat
    12361 cggcgataag gccgccgccg gcatgcatta gaccgccagc catcgtgtta aagaaagtac
    12421 tttccaacgc gttgctatag gtgaagtcgt caccttccgc cgccgctgcc agcccggtaa
    12481 gcggcacggt caccaacgcc tgcgctgccc ccatgcgtgc accagcaaca aatcgctcgc
    12541 caaatcggcc aagcacagaa gccgcctttg cttctccagc gaacggaacc agcgccagcg
    12601 ccacgttacc aggatctgcc attgaaccag ctaggctggc tgcgaaatta agcggcgtgg
    12661 ctacccaccc gctcggtgcc gacatcgcga tctgctggcg tgccagagaa tctttgcgtt
    12721 cggcaataac atgatcgaga aaagcctgcg taacgccaga atctggcacg tttatgctct
    12781 ttacgccgta ctgcttcagg agctcatccg cttcctgctt actgataact gtagagtttg
    12841 ggtcattcgc cagcgagtcg gcctgcgcaa agcggtagcc ggacatgacc ggcccctctt
    12901 caaatccctg cttaagggaa gaaagcagcg attcgccaag ccctgctggc gcgttgccaa
    12961 ttggctggtt aattccctgt cccggatcat ctgtgtaaat tggcatgtta tcgtcctgat
    13021 tgctggccgt tctggaaaat gttaatcagg ttgtcgcgct gactttctgc gctgtattcc
    13081 ttagactgtc cgggagtata tttcaccgga gtatcaatga acttggtaat gctgttccat
    13141 actgatcggt tggttgttcc cagtttcgcc agatcgttga acggcaccgt aatcgggttg
    13201 ccgtcggcac cgttgacgat cagcccgttg agcatcaggg taagtcctgt ttcgtcgctg
    13261 ttggtaaccc actgcgcatt atcacgaatg cgggagatac tctgctcacg gttgacctca
    13321 tcaggtagcc ttgggtcacc aataagcggc ataatctgat ctgctgacag gtttttcaga
    13381 tacgcattgg caccatcgtt aacgtcacga atatctatcc ctgcacgctt aggtagccgc
    13441 caagtgccat tggtctggta ctgctcgccg aggatgtcct gatacgcctg ttttgctgca
    13501 tcagacgccg acattccgcg ctgcatgttg atgtaagtaa gtcgttttcc ctgctcgttg
    13561 aagttattcc acacggcagt gccaccaggc tgaacaacca tcgtgccagc aaaatctttc
    13621 gattggtcat tccatgacga gtcggcgcta tccgcgtcgg ttttctcaag actgccgcgt
    13681 aagtcagcag ttttaacgct acggttttgc cagagcgcat ttgccgcgcg cgggttctcg
    13741 gtagccatga caacctgcaa cgcaggataa gcgctcttct gaacctgctg catcacctga
    13801 tccgagtatt tgccgaacga ctgcgccacc gactgaatgg cctttacgct agattcctgc
    13861 gtgttgtcaa tacgctgcag tacgtcgttg accatggact ccggtaaaac ttttttgctc
    13921 attatcccca ggcggtcttt ttcagactgt atgcgggaaa ccaggtattc accagatgaa
    13981 gggtcattca ggtactgctg gaatgcagcc tgcacaaccg gagagttttg ttgcagccat
    14041 gcccccggat ccgcttcccg cgccttcagt acctgcccaa gcttgacctt tgccgatgca
    14101 taaagctctg ctttgtattt aaagtcaggg tcgttttcct gcggtgccat tgcctgcacg
    14161 gcggcggtac cctgctggac gttgccctgc ataatggtct gataaacagg ttgtagcgtc
    14221 attgcctgct ggtattgctg gaaggttttt tccatctgca ggcgctcggc aggcgctgcc
    14281 tgaagcggca taacggcggc ccattcgtgc gctgaaatag gcgtcacctg cttaccggcc
    14341 tcaattttgg ataggtcgtc ctgcattcga ctctgtagcg caacgcgacc ggctgaagcc
    14401 tgcatgtcgt acatgccagc aaccttgctc atcatctgcg actttttgtc cggactcatg
    14461 gcgttccaga atggctgtgc gatgaggttt tccatcgtcg cagatccagg aataactcca
    14521 gcactgccag ttacttttgc cacataattg cgcgtctcgt cgtatgggat agctgcggca
    14581 aactgggcgt tactgacttc gcctgtgcgc ggatcgccaa tctgtttaat ccagccgtca
    14641 acctttcctg ggccagcgtt ataggcagct actgccagaa ccgggttatt gtcgtatttc
    14701 ttcatctgcg cgccgaaata agcttgcccc aagcgggcat tatagcgcgg gtcattcaac
    14761 catttatctc ggtcccacgg cacgccagca aggcgggcag cttcggggcc agtatcttcc
    14821 gtcacctgcg ctacgccaac agcgcctttt ggcgacacca gaggtgttcc gtcctttccg
    14881 tactgatttc cgccactctc ctgccagatt attgcagaga ataactgcgc ctcactcggt
    14941 gtatcggtta cctcaatctt gccgttcgga cccatcatct gttgatacat cggcacatac
    15001 cacgcctccg ccgcaccgtt cgcggcattc tcgcgccacg agacccagtt ctgttcgatc
    15061 tcttcctgac tctggccgtg ggcttcgccg taagcgatga tgctatgata tgccttcaat
    15121 cctgcctggt ttgccattgt cgggttacgg aactgcatcg ataggttttt tagtgtcgca
    15181 tcctgcatat ccgcctcata ctggcgaacc tgtcctattt cgtacctccc ggcctgcgta
    15241 gtgaactgaa tgcgctgctg ctgcgcctgc tgcatgaaag cattacgagc ctgttcatcc
    15301 ggcagcgaca tagccagttg ttcgacctga gcatcaaact gctgcgtata ctcatggcct
    15361 tttccaatag catttttccc tttcaggtta agcaatcctg tttcaggatt attcagcaga
    15421 tcgctgctta tctgactgag gttaagagat gcctcctgag ccagagcgat attggcacgc
    15481 tgttttgcct gccccaaaac atcaattgcc tctgtccctg cccgaacaaa agcatcacca
    15541 atacctggct gagaaaacgt ctgcaagcct gctgactgaa ctccacgact ctcaacctga
    15601 cgtccggata ctgttggtac gactggcatt ataatcctcc gggtaatctg gttcctgctg
    15661 ctaccccgat tggcgcagga gtgctttgag taaacggact ccacgtccca ccaaacatct
    15721 ggtacgcacc gtatgccttc agaggcgcag tgagcaatgt tgttgctgct cccacattcc
    15781 cctgtttacg ggctgaactg gcttctgctt tatagttggc agcctgaacc tgataaccgt
    15841 aagcctcgcg ttgcgcgtta ttcaccgtcg tcagcgaatc aagagcgcca aactgggcag
    15901 tgtcgccaaa tatatccagc gcgttacctg tagataaatc agcgccggta gcccccattg
    15961 tcgccgcctg tgtaccaagc cgctgtcggg tctctctgcg ccgttgctca gcttcagcgt
    16021 tacctctgtt tattgcatca tttgcctgag ctgtggctat atctgcgttc gcttctgcaa
    16081 ccttcgaggc atactttccc tgttggtact gggtgtatgc ctgaatgcca ctcatggcga
    16141 gcattgcgcc accagcaata accggatcgc acattatttt ctctccatgt gaaatctgtg
    16201 gaaattaaga ccaagagcac cataaggcgc ggcttcttca agcctgaatc caagccagtg
    16261 cagccatgct ttggcaacat ggtttcgctc gtcgacgtag ttttccaggc gcggataaac
    16321 tgccagcatc tgctgcaata cagggcggca gtggcgaaga aatgtcttct gatatttttc
    16381 aatacggctg gttcctacca gccagggcgt accattgcca ccgatcattg acgccggaga
    16441 tacgccaaac atggttacca gttctccgtt cgcaaatcct gaccaggcca tagtcgcagt
    16501 gcgaagacca acacgcagcg catcttcggt agtcatcagt gataccgcat acagttcgtc
    16561 aatatcagcc tgacgaacat ccggcaaaat catctgaaga tgctcttcgg ttgcgggaat
    16621 aatttgaaca tcgatcatca gaacccacca acagtaaggc gaggaataac ggcaagaaca
    16681 gacagcggca acggatcaag ctgacggatt tttacacgtc cgtttttgcc ccagttactg
    16741 tccagtttca cttctacttt tccggtagca tcatcaacag gatcatcgta gaactcgaat
    16801 tcacgctgtg gatattcgta ccatttgccg ccgggcgtag tcgcccagat gccgcggctg
    16861 gcattcacaa ccagagtaac ggaggggatc acctgttttt tgtccagcag cgtttcctgt
    16921 ccgttaatgt tgatatccag tgtttcgaat tcagcagtta ttggcaggcc gatgtgcaca
    16981 acagcccccg gagattccag cgtgacggca cctccggaaa caactttctg tggttccacg
    17041 ttcgcatcag agagaatgtt tacggtctgg ccttcaagat gagacaggcc tccaaatgtc
    17101 cggcgcgcca tctgccagtt cgtggtggcc acattcctga gggatggcgg gacgttcctg
    17161 ttagcacgaa ccactacagc ggtgttgctg gttacagaaa taatgtcgca acgtaattct
    17221 tttgacactt catcgccagt atcaggatca gttccggtat aagggaactg tagttgcgca
    17281 ccgacatcac tactggtgaa gtacgcacca ccagaaacac tgattgtata ttcctcgcgg
    17341 taatcccatt cgccagaacc accagtgatg atcatcgttc tgtcagacgt atttcttcca
    17401 tcatagctaa ggccagaatc aacaaagaaa gcatcttcat cgctggtaaa taaacggctg
    17461 gacagtcgct cgatgtatct cactgtttgc ccgttaacgg ttcggttaac gacgaaatac
    17521 accgcatctt cattgccttc actgatactg catgtgcttt catattttcc ggtactggat
    17581 tgtggtgccc atgcaaaaac ctgctgatca cgcaaatagg tcatcaccag taatttaccg
    17641 tcatcacgaa tgcagaaggc gctggagtaa gggacaatag agaagcacca gtcaacaatg
    17701 ctgtgcttct gaaaaagatg attggcaagg atggtcaggt cgttcccctg atagccgtca
    17761 acatcgaatg agtaggccag atcacggaca acactgcctt tctcctggac gaacagagca
    17821 atattcgcca cggcaattgg tgggacattg ctcgagccat ttgatccctg agagctgaat
    17881 gcaaatgatg atggggtaag cactttgttc tggtcgccag tgatgacgta ctcacctccg
    17941 gaagtcagcg ccaccagcga accaacatca atcaggtgac ggatctcatt aacctgacgc
    18001 ccggcatagg tgtagataat tctgtcgtca tcctgcgtag ggttgctttt gccaaaatcc
    18061 ttataatccc cggtacggct ggcccagata gtctgaggaa acgcagtcga tgcggcgaag
    18121 taaagacgtt gttgataata aacaacagtg ccaggataac cattaacact gttccaggca
    18181 tatttagccc atttatagct ggcattatcc tcgccaacta cctgcgaagg gatataggaa
    18241 atcacctcgg cagttgcagt agttccattt gcagcagaga tacgggcaat gccaaaacca
    18301 ctgtgcagat actcccactc aatgccggta tcatcatcac cggatccgcc ccagccatcc
    18361 catgatgtgc cttctgtatg cgaagggcgc aaagtgcctg ttttgcctac tgtaacggcg
    18421 cgatagtagt tactgtctgc acggcgaata tcgccaatcg acgtactctt actggtttcc
    18481 cataccggta ctgaatccac tgctggctgt tccagataga acaatttgcc tacctgctcc
    18541 gcgccaaaaa tagaggcgct tgccgttaac gtaattgtcc cggtgctggc gctggcataa
    18601 accgtcactg actcgtcaat attgatatct tcaaatggcc cgttcttcgt taccacatca
    18661 accagttgcc agttgtcatg cgcatagcgg cgcaactctt tcggcgggta tgccggatga
    18721 accagcgtaa gcacgtctgc gctttgcgtg aatttaattc tgaacagatc ggcttcagta
    18781 tatggcgtgg caatttcata aataacattg ctgctgttca gcaccaacgc accatctttg
    18841 ataacgcgca tgtactggtg tccgaactcc agagcatagg tctgaaccgt cgagaactgg
    18901 aacgggatca ggcggcattt ccgatttggg tatttggcgg caccaacaaa acgcgtacca
    18961 ggtcgattct caacgccgcc atactgccgc acgataaagt tatcgcactt gcgcaatgcc
    19021 acctggtact tcgccatgtc gatacgacca tacaacgatg gtccaatctc accaccggca
    19081 aagcttggct ggatccaact gatagccatc aggacaacct cgcaatggta aactcgtcaa
    19141 tcggtggctg tggttcctgt gattcattct ggctatgcga gccagcacta agaatcacgc
    19201 gattgtacat attgagggca aacgtaccga ggtctgcatt cccagtcagc gccatgttaa
    19261 tagctgccgc aagacgccag gccaacgcct ccataaaaat ggcatcaaac atgttcacat
    19321 ctgtaacgcg agagacatac ttgagccatg cctgaggctg gtctgtgtag atcaactttc
    19381 ctgttccgtt ggtgtctgca ccaacttcgt actgaacgcg cattggtgct gctggattgc
    19441 gtacaccagg aagcataatt tcagtaatgc gcagacaatc ggacgggtac tggtacgcat
    19501 attcccagtc aggcggtgga ttgctcgtat ctgcaagcgc cacgcgtttg gtagcaaagt
    19561 tccagtcaaa atcagaaagc acagcatcac ggcaggcctc aaagtgcagc gaacattccc
    19621 ccgcttcctt gctggcttcc gtcaggctgt taatgctgcg gctattgcca atattggaca
    19681 gcgcacgatt acagatctct actacagagg ccatcactca cctccgttac cgtacagagt
    19741 ttcagccgct gatttttcta catccccgga aacaggagca atcgccatat cagtgatctg
    19801 cagctcggcg ctgcgattaa caccatcgtc agtttctctg gcagacaggc ctcgaataac
    19861 agcctttgca gttatcatca cttctgttcc gacgccctga ggttgcgcct tcagcttatt
    19921 caatgtgtcg ttattaagag tgatgcacag cccccacggg tattcatcgc gagttctggt
    19981 ttctccgctc tcatcctggt agctgtcagt gccggttttg aggtttacga gttccatata
    20041 cactcctgca ataaaggggc cgaagcccct tgtctgattc gcgaggctta cacgcccagt
    20101 tctttacgct tatctgcgat cttctcgcgg agcgtttcgg ctttggcgtt atggtgtggc
    20161 ttctcgttaa agagcaattc gtactcttca cggagcttat ccagttcacc atcatctgac
    20221 acatcgttga tgattttggt gctggttgct gccatagaca cctttcctgc tacctttgct
    20281 tttgcctgtc tggctgcatc gttaacaggt tccagtgcgc taccaggctc accttcgtat
    20341 tcgatttctg ccccctccgg ccacagtgtg ttatggatat gagagaggcg cagaacgcgg
    20401 tatcttggtt tctcacctga catcgaaatc accttaacca gttacttttg agcggatcgg
    20461 gtacggtgta ttggcatcaa catccagact gatacccgca gtgaatttgc cagccgttag
    20521 tgggccagtt gcgacggagt agttaacacg cagatatcgc tgaacaccgg caggcacctt
    20581 tgcagaaaca actcgtttac ctgctgtcag ggtagccttt gccagtgcgc cactatcata
    20641 aatagtggac catgagctgt tattctcact cgtctgcaac tggatgttta cagttgcctc
    20701 accacttgcc gtggcggctt cgttaaccag cgcccaaaac tcaagcgggt aacccacgcc
    20761 gatatcgcga cgattaccat caattggacc tagatcgatt acgtcagtag aagccgcggt
    20821 atcagttacc gcctgtgctt cggagaacat caacagtttg tcggtgatca tcttctttct
    20881 ccattagtgg gtctgttacg acccactggt taataacagg cgttacacca cacgggcttc
    20941 tgtttccaga agcgcatcag tttcacggat tggtacacca cggaatgacg tccaccactc
    21001 gccttcagtc tcttttacgc taatcgccag agatgttttc tccagagatt gcagatcaag
    21061 agcctggcct acagtgcggt tcatgtagaa caccgggcga cccattccac ggtttggaat
    21121 gcgatgcagt gctttaacca tcaacttcgc aatatttgcg gcagaggaag gttctgaaag
    21181 attgctgaca tcgatgtttg caatgcgaac aacataacgc cagtcacgca gagcaagtcc
    21241 gttgtcccat ttgtaatggg tgcgatagcc ttcgtacttg ccgccatcag catcttccag
    21301 tgtcacctgg cctttatctt ccatctggat gccagccttc tgccctttcg ggaagatgcc
    21361 atgcacggtg ttttcgcccc acaccactaa ccagattgag gtgttatctg tacccgtgcc
    21421 accagcatca atgatgttct gagcattacc cgcagacagg ctggaatagc gggaggacag
    21481 tcccataaac tgctgagggt taacgctgga atcaccataa aacagcgtct gcgccatctg
    21541 ctgattcatc gcttcaataa atgcgcggtc ttcagacagg cggaattcag cggtattgcc
    21601 gttcagatca gccagtgact tatcgacttc agcataggtt tccagcatgc caacggaatc
    21661 ggttacctgc actgtggttg atttgcttgg ctgtacgcca tagttcagca aacgccaggt
    21721 agctgaaggt aaaccagaac gaatggtggt tcggtgtccg gtaggaaggt tcccttcgac
    21781 aaaaggcata tcctgaagga tcgggttagt ttgaccgaga agctcgataa tcttatcgac
    21841 tttcccgttt ggatcgacgc gcttacccca gtcagccagc gttagcgcag ttaagccttt
    21901 aacagacatt gtcatttcct ctcttatttg ccatagagca cttcggccgc actacgctgg
    21961 ccttcattac caccggtgac catgccatct tcagacatcg cctttccgat tttcacgaac
    22021 gttttgacca gatcagggtg attacccagc ccggtggtgt tcagatattc tttgagttca
    22081 ggtgtcccga actggtcaag cgcacgctgt gcggcgctaa ggttagaaat caacttgtcg
    22141 ccaccgattt ctttgtcagc ttttacatcc gcagcccact gctcggttgt tttctgccag
    22201 gcttctgcct ggcgctgctg aacacctgcc agaatcttcg gataagcatc aaccagcttt
    22261 tgcgcttgct cgttggtcag gttaagttct cgcgccaccg gctcgaattc cttcaacgct
    22321 tctgtatcca gctctacgcc ttcggcagcc tgaaactcgt acttctcagg cgcaccctct
    22381 ggtttatcgc cgtccttttt ttcatcctgc ttatcgtttt caggcttttt gtcatcagca
    22441 ggtttatcgc catcagcaac aggttgtggc ttatcacctt cctgttgtga tggatcacca
    22501 actggagcag ggttatcacc tgcaggcgct gacggttctg acgcagccgg agctgctcca
    22561 ccatcgactg gttgctcatt gcaaagacgg cgatacagca aacgctcaaa taaattcatg
    22621 atcactcctg ttcactggcc tctttggcca tcttcaaata ctgttcaggg caatgcgcca
    22681 taacgcgctg aaacagttcc agcgccagat tgcgttgccc ctcattaaat gccattgcca
    22741 tagcgtccat cggtgagatg gcggaaaaca cacggccttt ctcaagcacc gaccagacaa
    22801 cgcgacgccc ctgttcactg ctcatgacaa agcgaatgtc atcaatttca cgctgcgcca
    22861 tgtcacgttg cttacgggcg ttttcttctt tcagttgatc gtcttcgtaa tctgtcattg
    22921 tgattgccca ccctgaccac taactgcatt cgccatagct gacaacacac tcggatccga
    22981 agttttagct tcgcttagcg tcttggcacc ctgtgccgca gccatcccca tcgccatcat
    23041 ttgttgctgc tgttgctgct gtgcccgttg ctggcgagcc tgctcaacct gttcctgcgg
    23101 aacaatgacg gttggagaca ctccggacat atcagcgaat gcatcgatcg cctgatcaac
    23161 gttgagtttg tcgagagctt ctggtttcgc ttgcgcaagt tgaccaatga agttgaccgt
    23221 agacgccaga ctggacaggc cgatagactt ctgcgcctga gccatgacgg aaatgtattc
    23281 gaccttcagg ggcatacctt ccatcgcgtc aggcggtggc ggcagcatgt ttttacgcac
    23341 catcatcgag aaagcgcggt caatgagagg attaagacat tcgtcgttca gacgctccag
    23401 aaccggcccc aacatcagaa gtttttcttc tttcatttcg atcaccgctt caacaggcat
    23461 cgaacgggta ttgatgttct gcaacatcat gaacagatcg acaaagtagg cactgttaat
    23521 gatttgacga gtgtcctgaa tgtctgccac cagatctgct gtactggggt taaccagata
    23581 agcaggcctg aaaccatcct gaccagtaat ctgatcgata tacgtgatgt cgccaggaag
    23641 aagggaggcg cgctgattct tgagggaagt cggagcaacc atcggcggat tggtggcttt
    23701 atcaatcaac tgcgacttgc gcttctggag aagctgcaat gccttaacag gtccaagcgc
    23761 cagcataccc gggcatgatg atccataaac atcttcgccg ttaacttccc agcgcggagc
    23821 cataattgga aactcatcga atccggactc acgcaacaac ttgtcgttat caccgccaac
    23881 ctcgtaataa accgatttga atggcttgtt cttgctatcc agcttcgatg tatcgcggtc
    23941 aatgttcggg taaaccgaat gcatcacttc aatccacttc tcgtaggtgc cgctttccca
    24001 catgcttttt acggattcgc tgacgttatt tagcccgaac tcctgaacaa gctgacgaac
    24061 agtcatagag aacttgcgaa aacaggtgtc cacactgcca cgaggtgagt tagccaggta
    24121 gtaactgcct atagggaatg gcattgtgcg aatgatgtcc tcgtcatcct ccagcaccgc
    24181 cattgcacca gtgctgtatg tgccgaggct tccgtataac tgcggcagcg actgatagag
    24241 attcgactta ttgaacatat cgttcatgcg gttctgcacc gcctcaagcc acaacttaac
    24301 agggccataa tccatcattt caggatctgg cgtagccagg cgaaaccacg gacgcgcggg
    24361 gcttgtgatg cctgacatca tgccgctggc gagagtgcgc gccgccatag tcccggtcga
    24421 atcaataatg cgtgtattcc gtcgatcgtt acggttgacc tcagaagtca gaaagcggga
    24481 accacgcggg ttgatgtaat cactcaactc gcgccagtgc ggctcgaacg actgacgctc
    24541 gctttcaagt tgtgcgaact gtttgttcaa tcgctcttta gttgtttccg ccatttcaat
    24601 gactccggtt actgaccaag cagcgtttta ccgctggtat tagcggttga tgtgtcgccc
    24661 tgagaaccgg taagcagcgt agaactacga ccagcagcag cgcgacggcg acgtgtttct
    24721 tcgtcgcggg catcaacaac ggcggcatcc tgctcctgtg gtgctgcctg aacttctggt
    24781 gttgcaggca ctgatggtga gctaccaatg cacatatcaa tgactccgta cgcaattaaa
    24841 ttattaccaa tttaaccaca tatgatttat ttatcgtagg tagttgacat ttaacgcacg
    24901 aattattacc ttcaaggtaa ccaaagagct cattccggtt actaacctga ctggcttgtc
    24961 gttaaattga acaggtggag tgagctttta ttttgagcag tacggcgtat ggcacatgcg
    25021 tcgttagcgg tctggtgacg ttaaaggggt taccttttcc cctagctcag gcaacaaacc
    25081 aggtagccgg aatgtgcaag ccccgttcat atcgtcggac cgaggactca ccaccctggc
    25141 gattcggtgt gacgcctcgg aagagacgag ggtacaacga tgagagcatt tatggagccg
    25201 cgacaaagtg tggcgcctta acaggctaag tgctctcagt gttgtggcat tagctcagtc
    25261 ggacagagca accgccttct aagcggttgg tcgcaggttc gaatcctgca tgccacgcca
    25321 gaatcacgcc taaggaccgt gatgccagaa gttccgggtg cttggcggtg atggttccct
    25381 tgaaggacta tcaccgccct ttttacagca ggacgccatt gcgatgactt catgctgtaa
    25441 acccgtacag ccacggaagg cataactcat tgcttccagt tcgcccggtt cgccgggcat
    25501 ttttttaagg tgagattatg aacgaccagc aaatcgaaaa agaaatcatt gagaaaggca
    25561 aaacggcacc gcgcgttacg ccagaccata tcgaaggcat tattgctcag gaggcatatt
    25621 tcacagcaga agatggtgcc tttggcaaag ccataaaagc gaaacatact ggcggagagg
    25681 taaactacca gccgcacgaa tcactttctc tgctgacgtt ctgcgtcctg gtgctgcgca
    25741 acggcttcac cgtcaccgga gagagcgcct gtgcaagccc ggaaaacttt gatgcagaaa
    25801 ttggtcggaa gattgcccgg cagaatgctg taaacaaaat ctggatgctc gaaggttact
    25861 tgctgaagca gaagttaagc gagcaataac accgtgacat gtcacaaaca gccagtctat
    25921 gagctggctt tgttttatcc tcaccagagg atatcaacga cattatcccc accagcggat
    25981 taagcatagg gatcgtaatc tgtgatggcc ttgccttgct ggttctgctg cccgggaatt
    26041 cgcagacgct tcgacacagg gaacgcaaac gtcagcagta gcgcatcgcc tttacccggc
    26101 gaacgcccaa gtcgctcttt gatatcttcc ttcggttcga taacgatttt accgtccact
    26161 cgaactttat actctgccgc cgacaggtcg tccgctgttt cctggtcatc cagcatcccg
    26221 ccgagcctca gccatgtctt gcatgcattg aacatctccc cacgcttgtt gagcatctgc
    26281 gggtcagtag acgcgccacc gaacggaaca agttgccatg tgcgccccca accgtcaccg
    26341 attgacttca gaccggtacc gtaaccaaag tcgatgaaca ctgcgtcagc ctgatacagg
    26401 tcttcaaagt cagcgatacg cttcgccata atcagatcgt cagtagtctt gttgccagtc
    26461 cacagcacct tactgtgcag cccctgccgc aggtatatca ccgcgtcatc aacgcctgag
    26521 tatgccgggt caacgccgat tatcaccgga gcatgtgcaa cctgcgcagc ggttaccacc
    26581 cgtttcattg cctcatcagt aagaccggta gggataaact gcaattcaga tgcatcaggg
    26641 aatatgccgc gcacacggat tttaacgaag tcgctgtctt ccccgtagtc atcaacccat
    26701 ttctgcaact gctgtttgtt agtgccttcc accgtccggc tgtcaatctg cgcacacttc
    26761 cagcggtgtt tgtacttgcg gaaacattca cggaaacgcc cggtattacg cgtcgggttt
    26821 ccgaacgcca cccagataat ctcagtgtct tcgtccgtta gcgcaccctc ggcaacttcc
    26881 cacaccagat ccgcaatgtt cgacgcttca tcgaatacca cgatgatgcg tttgcgctcg
    26941 ttgtgtagtc cggcgaatgc ctcagtgttg tgctcagacc aggggattgc gtcagctcgc
    27001 cacagcttgt cgtgcccagg atcattgctg tacatcgcgg tagcggtaca ggtaaaccag
    27061 tctttcgtga tagcaaggtt cgaccacttg ataatttccg gccaggtctt cgttcgtagc
    27121 tggttgtcgg tgttggcggt caccacaacc ttacaatcct cgcaagtgga catgccccag
    27181 ttgatcagca ttgagatgaa tgcggattta ccaataccgt gacccgaagc gcgtgccagc
    27241 ataagcggct gatagcgcgt ctctggattc tgcaggtgat cacgtatctc tcggaacgca
    27301 tcagcctgcc actgacgtgg accggtggca tgtgctaatt cagtcccctc ttccccccac
    27361 gggaacgcat agagggcata gccaagcgga tcgtgagtga acactgcaat atcctcgatc
    27421 aactgctctt caggagataa cgctgtatct gtcactgatt accatcctga cgttctttga
    27481 gtcgcttcct ggctgctgct atgcgatcag caattgtcac attcacatta acatccaggc
    27541 gttctttgaa tgcgttgacg tcgacgtgct taccaatcag ttcgaggttc ttcaccttgt
    27601 ccggccattt caccttcttc aggatatgct cgacatcctc aacagacaga tccgcctcgc
    27661 cattctcttt ttgcagagag gcctgagtcg tcttgatagt agcgatatcc atcgcgctga
    27721 gagaggtgcg ccatacctta ggccactcag cgatcggctt catcccgccg tcgtcattca
    27781 agatatccag gacatccatc tggtcgatct ctaccaggcg catgaggacg taatcagcgc
    27841 tgacgcgcat tcgtttgttg cgctcctcca tcaactcggc aatccgtttt tgaatgcgtt
    27901 catcgcgcat catgacactg gctttaactg ccgctgtatt tggggagaat cctgcgttaa
    27961 tcgctgcctg agtctggttt tcaggcgttt tgatgtatga ctggcaataa gcctcctgca
    28021 ttgatgtgag cggcttaaat tgcgttgact tgcgtttata ggttttaggt tcagcaggca
    28081 tcataaccac catggtaata gttaccgttg tggtaatagt accatgcaaa ataaagccgc
    28141 catagttggc ggcagtattc aaaacccgtc aaattcatca tgcataatct actcgtgaca
    28201 tgtcacacta ttaatttcgt ttcatgccag cctttagtca cccagcattg cgagtcacca
    28261 ttacacgggc atgaattaac tggaactctc tcgccgcact taccgcaacg ttttctgctg
    28321 atcgatttta tacgcccgcg cacacgtgca tcatcctggc ggatcagtaa cgctatatac
    28381 tcaccaaatt cgtaaggcgc acgcccgggg cgacgcgtgg cacagttacg ctccagcatt
    28441 tgaatttcct gagcatcaag cacaatttcc agcttacgca cgccagatgc agcttgtctg
    28501 gctctctgag cggctttgcg ctctgctgct gatttagcca ttctgatttt cctgcatcat
    28561 gagaaagaca atcatggcgg cacggagtgg attgtcatat gcgacaccaa cattcggtcc
    28621 ggcatcatca aacaagtccc ttgcgttgtc tgtagcgcac ggcattgagg gattgtctaa
    28681 aattatgctg atgttgtttt cagtgataat cggccatgcg tctgctgggt ttgcgcatgg
    28741 gttaaaggaa ccgcgctcaa cttctacttc aactgcgtct ccgtttacaa tgtctccctc
    28801 aaatgagaca aacaccatat cgccattctc accttctttg taatccggtg atccgttatg
    28861 aatggcttcg aataccgcca cgttaatttc aaaatcactt aactgtgaat agtccatcat
    28921 ttcacctcct gcggcggttc tggtagaggc atccagtggg ttacctcttt gagatacagg
    28981 tcttcgccac caccgtcatc ccaagtggga ttgccatcat taaaccagtc gccatatacg
    29041 ccgacctgag tgttggggat gtttggtggg tagttgtttt taaagtcagc tgctaacaca
    29101 tagcattgtc gctctcccat ttctggcatt cgctcactac agcttatcca accatccgga
    29161 gttaccggag agttgccacc ctgaacagta ggcatatccg gacctttgcg aatcgccttg
    29221 gcaagatcga ttgggtcgtc gtacaaccag tcacctgttt gcggatgatt ggcttctgcc
    29281 aattgtgcag cccactccag gccgtctttg tgtccttgca gatagtccag cggtaactca
    29341 tcactattac ttacaggttc ggcctgaagc atggcggcgc ggcattgatt ccatccgttg
    29401 gcataattta aggaatatcg gacgccatct ttcacatact taaagcccat cccatctttc
    29461 agtttcggta tttcatctgg cacagatacc ggcgctggct gcgttaactg tggtgccatc
    29521 agtgactcca attcagcgat acgcttctca gctgcttcta tcagtttcgc ggcatccgct
    29581 gccagttcgg taacgtcaat ggtggcacag ccttctaatc cgttgcgatc ctctccataa
    29641 acatcaaact ccccgccatc aatatcacta gcatcgtatg cagccagttc gttcaggaac
    29701 cataaaacgt tatcgccgta acgcagagcc tgtttgttga gtgctttcat tggggctgcc
    29761 tcctggcgaa gtttgtcggc gaactcgcta agggatatgt agcaatctcc gaatgttaac
    29821 gaaccgctcg actgcatatg ctccatggcc atctccacac cctgcgcccg tacttcagcc
    29881 agaaaagcat cggtggctgg ggtttcaaca cggatgctgt cgcgcaagat gaaaaatgca
    29941 ttgagcattc cagtctctgg cacttcatcc tgatgcttct catacgcatc aagagccttc
    30001 atcatctcag gtccgaatgg ttgagggtgc gcagccttca gcgccgcatt ctccgctgcc
    30061 agcgccgaaa acttctcgtg tgccaactta acagccgcat cagcctgctt aattgactca
    30121 atcgctttct ggtggtcttc ggccagcgca ttagcacgca ccagttgcac ttccagttgc
    30181 gttgccaaat cgctgatcag ctttgccacg ctgcgcatat caacggcacc acattcagct
    30241 ttcagttccg aagccatctc atgcccggcg gcaactaacc ctttgatatt actttccatc
    30301 tttaccctcg cttatccaca taacttattg attacattga taactaaata gatcgtcgat
    30361 tcagaactct tcgatgttcc agccaccacc tgctttcttt ggtttaaccg ttaccccgat
    30421 gattcggaac ggatactgat ctgcggcgac tttggttttc actctggcgt catcggtcca
    30481 gaatccccct ttcacttcgt gcagctccat ctcgccggtg gcgagcatca cagcgaaatc
    30541 gggcgtatag aacgtgttat tagctaaccg cagcttgata ccctcgaatc gataccaggc
    30601 gatttcccct gcacgtttac gcagctcaag gtgctggcaa tacgcagatt ctgttttgtt
    30661 catctggcct gttttg
//
LOCUS       DADXDL010000061        30421 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.061, whole genome shotgun sequence.
ACCESSION   DADXDL010000061 DADXDL010000000
VERSION     DADXDL010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30421)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30421)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30421
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.061"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..618
                     /gene="tuf"
                     /locus_tag="IRB70_003047"
     CDS             <1..618
                     /gene="tuf"
                     /locus_tag="IRB70_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312930.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBC0632931.1"
                     /translation="LELAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVE
                     RGIIKVGEEVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQ
                     VLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVE
                     MVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAKVLS"
     gene            848..1231
                     /gene="secE"
                     /locus_tag="IRB70_003048"
     CDS             848..1231
                     /gene="secE"
                     /locus_tag="IRB70_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007665874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBC0632932.1"
                     /translation="MSANTEAQGSGRGLEAMKWVVVVALLLVAIVGNYLYRDIMLPLR
                     ALAVVILIAAAGGVALLTTKGKATVAFAREARTEVRKVIWPTRQETLHTTLIVAAVTA
                     VMSLILWGLDGILVRLVSFITGLRF"
     gene            1233..1778
                     /gene="nusG"
                     /locus_tag="IRB70_003049"
     CDS             1233..1778
                     /gene="nusG"
                     /locus_tag="IRB70_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005280494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBC0632933.1"
                     /translation="MSEAPKKRWYVVQAFSGFEGRVATSLREHIKLHNMEDLFGEVMV
                     PTEEVVEIRGGQRRKSERKFFPGYVLVQMVMNDASWHLVRSVPRVMGFIGGTSDRPAP
                     ISDKEVDAIMNRLQQVGDKPRPKTLFEPGEMVRVNDGPFADFNGVVEEVDYEKSRLKV
                     SVSIFGRATPVELDFSQVEKA"
     gene            1937..2365
                     /gene="rplK"
                     /locus_tag="IRB70_003050"
     CDS             1937..2365
                     /gene="rplK"
                     /locus_tag="IRB70_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006121495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBC0632934.1"
                     /translation="MAKKVQAYVKLQVAAGMANPSPPVGPALGQQGVNIMEFCKAFNA
                     KTDSIEKGLPIPVVITVYADRSFTFVTKTPPAAVLLKKAAGIKSGSGKPNKDKVGKIS
                     RAQLQEIAQTKAADMTGADIEAMTRSIEGTARSMGLVVED"
     gene            2369..3073
                     /gene="rplA"
                     /locus_tag="IRB70_003051"
     CDS             2369..3073
                     /gene="rplA"
                     /locus_tag="IRB70_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBC0632935.1"
                     /translation="MAKLTKRMRVIREKVDATKQYDINEAIALLKELATAKFVESVDV
                     AVNLGIDARKSDQNVRGATVLPHGTGRSVRVAVFTQGANAEAAKAAGAELVGMEDLAD
                     QIKKGEMNFDVVIASPDAMRVVGQLGQVLGPRGLMPNPKVGTVTPNVAEAVKNAKAGQ
                     VRYRNDKNGIIHTTIGKVDFDADKLKENLEALLVALKKAKPTQAKGVYIKKVSISTTM
                     GAGVAVDQAGLSASVN"
     gene            3365..3862
                     /gene="rplJ"
                     /locus_tag="IRB70_003052"
     CDS             3365..3862
                     /gene="rplJ"
                     /locus_tag="IRB70_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBC0632936.1"
                     /translation="MALNLQDKQAIVAEVSEVAKGALSAVVADSRGVTVDKMTELRKA
                     GREAGVYMRVVRNTLLRRAVEGTPFECLKDAFVGPTLIAYSMEHPGAAARLFKEFAKA
                     NAKFEVKAAAFEGELIPASQIDRLATLPTYEEAIARLMATMKEASAGKLVRTLAAVRD
                     AKEAA"
     gene            3929..4294
                     /gene="rplL"
                     /locus_tag="IRB70_003053"
     CDS             3929..4294
                     /gene="rplL"
                     /locus_tag="IRB70_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBC0632937.1"
                     /translation="MSITKDQIIEAVAAMSVMDVVELISAMEEKFGVSAAAAVAVAAG
                     PVEAAEEKTEFDVILKAAGANKVAVIKAVRGATGLGLKEAKDLVESAPAALKEGVSKD
                     DAEALKKALEEAGAEVEVK"
     gene            4614..8642
                     /gene="rpoB"
                     /locus_tag="IRB70_003054"
     CDS             4614..8642
                     /gene="rpoB"
                     /locus_tag="IRB70_003054"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004870488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBC0632938.1"
                     /translation="MVYSYTEKKRIRKDFGKRPQVLDVPYLLSIQLDSFQKFIEQDPE
                     GQYGLEAAFRSVFPIQSYSGNSELQYVSYRLGEPVFDVQECQIRGVTYSAPLRVKLRL
                     VIYEREAPEGTVKDIKEQEVYMGEIPLMTDNGTFVINGTERVIVSQLHRSPGVFFDSD
                     KGKTHSSGKVLYNARIIPYRGSWLDFEFDPKDNLFVRIDRRRKLPATIILRALNYTTE
                     QILDLFFEKVIFEIRDNKLQMELVPERLRGETASFDIEANGKVYVEKGRRITARHIRQ
                     LEKDDVKLIEVPVEYIAGKVVAKDYIDESTGELICAANMELSLDLLAKLSQSGHKRIE
                     TLFTNDLDHGPYISETLRVDPTNDRLSALVEIYRMMRPGEPPTREAAESLFENLFFSE
                     DRYDLSAVGRMKFNRSLLREEIEGSGILSKDDIIDVMKKLIDIRNGKGEVDDIDHLGN
                     RRIRSVGEMAENQFRVGLVRVERAVKERLSLGDLDTLMPQDMINAKPISAAVKEFFGS
                     SQLSQFMDQNNPLSEITHKRRISALGPGGLTRERAGFEVRDVHPTHYGRVCPIETPEG
                     PNIGLINSLSVYAQTNEYGFLETPYRKVTDGVVTDEIHYLSAIEEGNYVIAQANSNLD
                     EEGHFVEDLVTCRSKGESSLFSRDQVDYMDVSTQQVVSVGASLIPFLEHDDANRALMG
                     ANMQRQAVPTLRADKPLVGTGMERAVAVDSGVTAVAKRGGVVQYVDASRIVIKVNEDE
                     MYPGEAGIDIYNLTKYTRSNQNTCINQMPCVSLGEPVERGDVLADGPSTDLGELALGQ
                     NMRVAFMPWNGYNFEDSILVSERVVQEDRFTTIHIQELACVSRDTKLGPEEITADIPN
                     VGEAALSKLDESGIVYIGAEVTGGDILVGKVTPKGETQLTPEEKLLRAIFGEKASDVK
                     DSSLRVPNGVSGTVIDVQVFTRDGVEKDKRALEIEEMQLKQAKKDLSEELQILEAGLF
                     SRIRAVLVAGGVEAEKLDKLPRDRWLELGLTDEEKQNQLEQLAEQYDELKHEFEKKLE
                     AKRRKITQGDDLAPGVLKIVKVYLAVKRRIQPGDKMAGRHGNKGVISKINPIEDMPYD
                     ENGTPVDIVLNPLGVPSRMNIGQILETHLGMAAKGIGDKINAMLKQQQEVAKLREFIQ
                     RAYDLGADVRQKVDLSTFSDEEVMRLAENLRKGMPIATPVFDGAKEAEIKELLKLGDL
                     PTSGQIRLYDGRTGEQFERPVTVGYMYMLKLNHLVDDKMHARSTGSYSLVTQQPLGGK
                     AQFGGQRFGEMEVWALEAYGAAYTLQEMLTVKSDDVNGRTKMYKNIVDGNHQMEPGMP
                     ESFNVLLKEIRSLGINIELEDE"
     gene            8719..12942
                     /gene="rpoC"
                     /locus_tag="IRB70_003055"
     CDS             8719..12942
                     /gene="rpoC"
                     /locus_tag="IRB70_003055"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBC0632939.1"
                     /translation="MKDLLKFLKAQTKTEEFDAIKIALASPDMIRSWSFGEVKKPETI
                     NYRTFKPERDGLFCARIFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTQTKVRRERM
                     GHIELASPTAHIWFLKSLPSRIGLLLDMPLRDIERVLYFESYVVIEGGMTNLERQQIL
                     TEEQYLDALEEFGDEFDAKMGAEAIQALLKSMDLEQECEQLREELNETNSETKRKKLT
                     KRIKLLEAFVQSGNKPEWMILTVLPVLPPDLRPLVPLDGGRFATSDLNDLYRRVINRN
                     NRLKRLLDLAAPDIIVRNEKRMLQEAVDALLDNGRRGRAITGSNKRPLKSLADMIKGK
                     QGRFRQNLLGKRVDYSGRSVITVGPYLRLHQCGLPKKMALELFKPFIYGKLELRGLAT
                     TIKAAKKMVEREEAVVWDILDEVIREHPVLLNRAPTLHRLGIQAFEPVLIEGKAIQLH
                     PLVCAAYNADFDGDQMAVHVPLTLEAQLEARALMMSTNNILSPANGEPIIVPSQDVVL
                     GLYYMTRDCVNAKGEGMVLTGPKEAERLYRSGLASLHARVKVRITEYEKDANGELVAK
                     TSLKDTTVGRAILWMIVPKGLPYTIVNQALGKKAISKMLNTCYRILGLKPTVIFADQI
                     MYTGFAYAARSGASVGIDDMVIPEKKHEIISEAEAEVAEIQEQFQSGLVTAGERYNKV
                     IDIWAAANDRVSKAMMDNLQTETVINRDGQEEKQVSFNSIYMMADSGARGSAAQIRQL
                     AGMRGLMAKPDGSIIETPITANFREGLNVLQYFISTHGARKGLADTALKTANSGYLTR
                     RLVDVAQDLVVTEDDCGTHEGIMMTPVIEGGDVKEPLRDRVLGRVTAEDVLKPGTADI
                     LVPRNTLLHEQWCDLLEENSVDAVKVRSVVSCDTDFGVCAHCYGRDLARGHLINKGEA
                     IGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAESSIQVKNKGSIKLSNVKSVVNSSGK
                     LVITSRNTELKLIDEFGRTKESYKVPYGAVLAKGDGEQVAGGETVANWDPHTMPVITE
                     VSGFVRFTDMIDGQTITRQTDELTGLSSLVVLDSAERTAGGKDLRPALKIVDAQGNDV
                     LIPGTDMPAQYFLPGKAIVQLEDGVQISSGDTLARIPQESGGTKDITGGLPRVADLFE
                     ARRPKEPAILAEISGIVSFGKETKGKRRLVITPVDGSDPYEEMIPKWRQLNVFEGERV
                     ERGDVISDGPEAPHDILRLRGVHAVTRYIVNEVQDVYRLQGVKINDKHIEVIVRQMLR
                     KATIVNAGSSDFLEGEQVEYSRVKIANRELEANGKVGATYSRDLLGITKASLATESFI
                     SAASFQETTRVLTEAAVAGKRDELRGLKENVIVGRLIPAGTGYAYHQDRMRRRAAGEA
                     PAAPQVTAEDASASLAELLNAGLGGSDNE"
     gene            complement(13184..14317)
                     /gene="thiH"
                     /locus_tag="IRB70_003056"
     CDS             complement(13184..14317)
                     /gene="thiH"
                     /locus_tag="IRB70_003056"
                     /EC_number="4.1.99.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000787958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-iminoacetate synthase ThiH"
                     /protein_id="HBC0632940.1"
                     /translation="MKTFSDRWRQLDWDDIRLRINGKTAADVERALNASQLTRDDMMA
                     LLSPAASGYLEPLAQRAQRLTRQRFGNTVSFYVPLYLSNLCANDCTYCGFSMSNRIKR
                     KTLDEADIARESAAIREMGFEHLLLVTGEHQAKVGMDYFRRHLPALREQFSSLQMEVQ
                     PLAEAEYAELKQLGLDGVMVYQETYHEATYARHHLKGKKQDFFWRLETPDRLGRAGID
                     KIGLGALIGLSDSWRVDCYMVAEHLLWLQQHYWQSRYSVSFPRLRPCTGGIEPASIMD
                     ERQLVQTICAFRLLAPEIELSLSTRESPWFRDRVIPLAINNVSAFSKTQPGGYADNHP
                     ELEQFSPHDDRRPEAVAAALTAQGLQPVWKDWDSYLGRASQRP"
     gene            complement(14314..15084)
                     /gene="thiG"
                     /locus_tag="IRB70_003057"
     CDS             complement(14314..15084)
                     /gene="thiG"
                     /locus_tag="IRB70_003057"
                     /EC_number="2.8.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418418.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole synthase"
                     /protein_id="HBC0632941.1"
                     /translation="MLHIADKTFDSHLFTGTGKFASSQLMVESIRASGSQLVTLAMKR
                     VDLRQHNDAILEPLIAAGVTLLPNTSGAKTAEEAIFAAHLAREALGANWLKLEIHPDA
                     RWLLPDPIETLKAAETLVQQGFVVLPYCGADPVLCKRLEEVGCAAVMPLGAPIGSNQG
                     LETRAMLEIIIQQATVPVVVDAGIGVPSHAAQALEMGADAVLVNTAIAVADDPVNMAK
                     AFRLAVEAGLLARQSGPGSRSHFAHATSPLTGFLEASA"
     gene            complement(15086..15286)
                     /gene="thiS"
                     /locus_tag="IRB70_003058"
     CDS             complement(15086..15286)
                     /gene="thiS"
                     /locus_tag="IRB70_003058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfur carrier protein ThiS"
                     /protein_id="HBC0632942.1"
                     /translation="MQILFNDQPMQCAAGQTVHELLEQLDQRQAGAALAINQQIVPRE
                     QWAQHIVQDGDQILLFQVIAGG"
     gene            complement(15270..16025)
                     /gene="thiF"
                     /locus_tag="IRB70_003059"
     CDS             complement(15270..16025)
                     /gene="thiF"
                     /locus_tag="IRB70_003059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312942.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiazole biosynthesis adenylyltransferase ThiF"
                     /protein_id="HBC0632943.1"
                     /translation="MNDRDFMRYSRQILLDDIALDGQQKLLDSQVLIIGLGGLGTPAA
                     LYLAGAGVGTLVLADDDDVHLSNLQRQILFTTEDIDRPKSQVSHQRLTQLNPDIQLMA
                     LQQRLTGETLKDAVAQADVVLDCTDNMATRQEINAACVALNTPLITASAVGFGGQLMV
                     LTPPWEQGCYRCLWPDNQEPERNCRTAGVVGPVVGVMGTLQALEAIKLLSGIETPAGE
                     LRLFDGKSSQWRSLALRRASGCPVCGGSNADPV"
     gene            complement(16018..16653)
                     /gene="thiE"
                     /locus_tag="IRB70_003060"
     CDS             complement(16018..16653)
                     /gene="thiE"
                     /locus_tag="IRB70_003060"
                     /EC_number="2.5.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine phosphate synthase"
                     /protein_id="HBC0632944.1"
                     /translation="MYQPEFPPVPFRLGLYPVVDSVQWIERLLDAGVRTLQLRIKDRR
                     DEEVEADVVAAIALGRRYNARLFINDYWRLAIKHQAYGVHLGQEDLQATDLSAIRAAG
                     LRLGVSTHDDMEIDVALAAHPSYIALGHVFPTQTKQMPSAPQGLEQLARHVERLVDYP
                     TVAIGGISLARAPEVIATGVGSIAVVSAITQAADWRLATAQLLEIAGAGDE"
     gene            complement(16653..18548)
                     /gene="thiC"
                     /locus_tag="IRB70_003061"
     CDS             complement(16653..18548)
                     /gene="thiC"
                     /locus_tag="IRB70_003061"
                     /EC_number="4.1.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomethylpyrimidine synthase ThiC"
                     /protein_id="HBC0632945.1"
                     /translation="MSATKLTRREQRAQAQHFIDTLEGTAFPNSKRIYITGTHPGVRV
                     PMREIQLSPTLIGGSKEQPQYEENEAIPVYDTSGPYGDPQIAIDVQQGLAKLRQPWID
                     ARGDTEELTVRSSDYTKARLADDGLDELRFSGLLTPKRAKAGRRVTQLHYARQGIITP
                     EMEFIAIRENMGRERIRSEVLRHQHPGMSFGARLPENITAEFVRDEVAAGRAIIPANI
                     NHPESEPMIIGRNFLVKVNANIGNSAITSSIEEEVEKLVWSTRWGADTVMDLSTGRYI
                     HETREWILRNSPVPIGTVPIYQALEKVNGIAEDLSWEAFRDTLLEQAEQGVDYFTIHA
                     GVLLRYVPMTAKRLTGIVSRGGSIMAKWCLSHHQENFLYQHFREICEICAAYDVSLSL
                     GDGLRPGSVQDANDEAQFAELHTLGELTKIAWEYDVQVMIEGPGHVPMQMIRRNMTEE
                     LEHCHEAPFYTLGPLTTDIAPGYDHFTSGIGAAMIGWFGCAMLCYVTPKEHLGLPNKE
                     DVKQGLITYKIAAHAADLAKGHPGAQIRDNAMSKARFEFRWEDQFNLALDPFTARAYH
                     DETLPQESGKVAHFCSMCGPKFCSMKISQEVRDYAAAQTIEVGMADMSENFRARGGEI
                     YLRKEEA"
     regulatory      complement(18629..18729)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(18781..19257)
                     /gene="rsd"
                     /locus_tag="IRB70_003062"
     CDS             complement(18781..19257)
                     /gene="rsd"
                     /locus_tag="IRB70_003062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma D regulator"
                     /protein_id="HBC0632946.1"
                     /translation="MLNQLDNLTERVRGSNKLVDRWLHVRKHLLVAYYNLVGIKPGKE
                     SYMRLNEKALDDFCQSLVDYLSAGHFSIYERILHKLEGNGQLARAAKIWPQLEANTQQ
                     IMDYYDSSLETAIDHDNYLEFQQVLSDIGEALEARFVLEDKLILLVLDAARVKHPA"
     gene            19352..20125
                     /gene="nudC"
                     /locus_tag="IRB70_003063"
     CDS             19352..20125
                     /gene="nudC"
                     /locus_tag="IRB70_003063"
                     /EC_number="3.6.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) diphosphatase"
                     /protein_id="HBC0632947.1"
                     /translation="MDRIIEKLDHGWWVVSHEQKLWLPKGELPYGEAANFDLVGQRAL
                     QIGEWQGEPVWLVQQQRRHDMGSVRQVIDLDVGLFQLAGRGVQLAEFYRSHKYCGYCG
                     HEMYPSKTEWAMLCNHCRERYYPQIAPCIIVAIRRDDSILLAQHTRHRNGVHTVLAGF
                     VEVGETLEQAVAREVMEESGIKVKNLRYVTSQPWPFPQSLMTAFMAEYDSGEIVIDPK
                     ELLEANWYRYDDLPLLPPPGTVARRLIEDTVAMCRAEYE"
     gene            20165..21229
                     /gene="hemE"
                     /locus_tag="IRB70_003064"
     CDS             20165..21229
                     /gene="hemE"
                     /locus_tag="IRB70_003064"
                     /EC_number="4.1.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uroporphyrinogen decarboxylase"
                     /protein_id="HBC0632948.1"
                     /translation="MTELKNDRYLRALLRQPVDVTPVWMMRQAGRYLPEYKATRAQAG
                     DFMSLCKNAELACEVTLQPLRRYPLDAAILFSDILTVPDAMGLGLYFEAGEGPRFTSP
                     VTCKADVDKLPIPDPEDELGYVMNAVRTIRRELKGEVPLIGFSGSPWTLATYMVEGGS
                     SKAFTVIKKMMYADPQALHALLDKLAKSVTLYLNAQIKAGAQAVMIFDTWGGVLTGRD
                     YQQFSLYYMHKIVDGLLRENDGRRVPVTLFTKGGGQWLEAMAETGCDALGLDWTTDIA
                     DARRRVGNKVALQGNMDPSMLYAPPARIEEEVASILAGFGHGEGHVFNLGHGIHQDVP
                     PEHAGVFVEAVHRLSAPYHL"
     gene            21239..21910
                     /gene="nfi"
                     /locus_tag="IRB70_003065"
     CDS             21239..21910
                     /gene="nfi"
                     /locus_tag="IRB70_003065"
                     /EC_number="3.1.21.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease V"
                     /protein_id="HBC0632949.1"
                     /translation="MDLASLRAQQIELASSVIREDRLDKDPPDLIAGADVGFEQGGEV
                     TRAAMVLLKYPSLELVEYKVARIATTMPYIPGFLSFREYPALLAAWEMLSQKPDLVFV
                     DGHGISHPRRLGVASHFGLLVDVPTIGVAKKRLCGKFEPLSSEPGALAPLMDKGEQLA
                     WVWRSKARCNPLFIATGHRVSVDSALAWVQRCMKGYRLPEPTRWADAVASERPAFVRY
                     TANQP"
     gene            21953..22543
                     /locus_tag="IRB70_003066"
     CDS             21953..22543
                     /locus_tag="IRB70_003066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjaG family protein"
                     /protein_id="HBC0632950.1"
                     /translation="MLQNPIHLRLERLESWQHVTFMACLCERMYPNYAMFCQQTGFGD
                     GQIYRRILDLIWETLTVKDAKVNFDSQLEKFEEAIPSADDFDLYGVYPAIDACVALSE
                     LVHSRLSGETLEHAVEVSKTSITTVAMLEMTQAGREMSDEELKENPAVEQEWDIQWEI
                     FRLLAECEERDIELIKGLRADLREAGESNIGIIFQQ"
     gene            22730..23002
                     /gene="hupA"
                     /locus_tag="IRB70_003067"
     CDS             22730..23002
                     /gene="hupA"
                     /locus_tag="IRB70_003067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017460010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein HU-alpha"
                     /protein_id="HBC0632951.1"
                     /translation="MNKTQLIDVIAEKAELSKTQAKAALESTLAAITESLKEGDAVQL
                     VGFGTFKVNHRAERTGRNPQTGKEIKIAAANVPAFVSGKALKDAVK"
     gene            23015..23710
                     /locus_tag="IRB70_003068"
     CDS             23015..23710
                     /locus_tag="IRB70_003068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709795.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1481 domain-containing protein"
                     /protein_id="HBC0632952.1"
                     /translation="MNSFNEGVVSPLLSFWRRSLMLAGALFLTACSHNSSLPPFTASG
                     FAEDQGAVRIWRKDSGDNVHLLAVFSPWRSGDTTTREYRWQGDNLTLININVYSKPPV
                     NIRARFDDRGDLSFMQRESDGEKQQLSNDQIDLYRYRADQIRQISDALRQGRVVLRQG
                     RWHAMEQTVTTCEGQTIKPDLDSQAIAHIERRQSRSSVDVSVAWLEAPEGSQLLLVAN
                     SDFCRWQPNEKTF"
     gene            complement(23712..24137)
                     /gene="zraP"
                     /locus_tag="IRB70_003069"
     CDS             complement(23712..24137)
                     /gene="zraP"
                     /locus_tag="IRB70_003069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312952.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc resistance sensor/chaperone ZraP"
                     /protein_id="HBC0632953.1"
                     /translation="MKRNTKIALVMMALSAMAMGSTSAFAHGGHGMWQQNAAPLTSEQ
                     QTAWQKIHNDFYAQSSALQQQLVTKRYEYNALLAANPPDSSKINAVAKEMENLRQSLD
                     ELRVKRDIAMAEAGIPRGAGMGMGYGGCGGGGHMGMGHW"
     gene            24375..25751
                     /gene="zraS"
                     /locus_tag="IRB70_003070"
     CDS             24375..25751
                     /gene="zraS"
                     /locus_tag="IRB70_003070"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     ZraS"
                     /protein_id="HBC0632954.1"
                     /translation="MRFMQRSKDSLAKWLSAILPVVIVGLVGLFAVTVIRDYGRETAA
                     ARQTLLEKGSVLIRALESGSRVGMGMRMHHAQQQALLEEMAGQPGVRWFAVTDEQGTI
                     VMHSNSGMVGKQLYSPQEMQQLHPGDEEAWRRIDSADGEPVLEIYRQFQPMFAAGMHR
                     MRHMQQYAATPQAIFIAFDASNIVSAEDREQRNTLIILFALATVLLASVLSFFWYRRY
                     LRSRQLLQDEMKRKEKLVALGHLAAGVAHEIRNPLSSIKGLAKYFAERAPAGGEAHQL
                     AQVMAKEADRLNRVVSELLELVKPTHLALQAVDLNTLINHSLQLVSQDANSREIQLRF
                     TANDTLPEIQADPDRLTQVLLNLYLNAIQAIGQHGVISVVANESGAGVKISVTDSGKG
                     IAADQLEAIFTPYFTTKAEGTGLGLAVVHNIVEQHGGTIQVASQEGKGATFTLWLPVN
                     ITRKDPQG"
     gene            25748..27073
                     /gene="zraR"
                     /locus_tag="IRB70_003071"
     CDS             25748..27073
                     /gene="zraR"
                     /locus_tag="IRB70_003071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-54-dependent response regulator
                     transcription factor ZraR"
                     /protein_id="HBC0632955.1"
                     /translation="MTHDNIDILVVDDDISHCTILQALLRGWGYNVALANSGRQALEQ
                     VREQVFDLVLCDVRMAEMDGIATLKEIKALNPAIPVLIMTAYSSVETAVEALKTGALD
                     YLIKPLDFDNLQATLEKALAHTHSVDAETPAVSASQFSMVGKSPAMQHLLSEIALVAP
                     SEATVLIHGDSGTGKELVARAIHASSARSEKPLVTLNCAALNESLLESELFGHEKGAF
                     TGADKRREGRFVEADGGTLFLDEIGDISPMMQVRLLRAIQEREVQRVGSNQTISVDVR
                     LIAATHRDLAAEVNAGRFRQDLYYRLNVVAIEVPSLRQRREDIPLLANHFLQRFAERN
                     RKAVKGFTPQAMDLLIHYDWPGNIRELENAVERAVVLLTGEYISERELPLAIASTPIP
                     LVQSQDIQPLVEVEKEVILAALEKTGGNKTEAARQLGITRKTLLAKLSR"
     gene            complement(27070..28359)
                     /gene="purD"
                     /locus_tag="IRB70_003072"
     CDS             complement(27070..28359)
                     /gene="purD"
                     /locus_tag="IRB70_003072"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBC0632956.1"
                     /translation="MKVLVIGNGGREHALAWKAAQSPLVETVFVAPGNAGTALEPALQ
                     NVDIGVTDIPALLDFAQNEKVDLTIVGPEAPLVKGVVDTFRAAGLKIFGPTAGAAQLE
                     GSKAFTKDFLARHKIPTAEYQNFTEVEPALAYLREKGAPIVIKADGLAAGKGVIVAMT
                     LEEAEAAVHDMLAGNAFGDAGHRIVIEEFLDGEEASFIVMVDGEHVLPMATSQDHKRV
                     GDKDTGPNTGGMGAYSPAPVVTDEVHQRTMERIIWPTVKGMAAEGNTYTGFLYAGLMI
                     DKQGNPKVIEFNCRFGDPETQPIMLRMKSDLVELCLAACEGKLDEKTSEWDERASLGV
                     VMAAGGYPGDYRTGDVIHGLPLEEVSDGKVFHAGTKLADDEQVVTSGGRVLCVTALGH
                     TVAEAQKRAYALMTDIHWDDCFCRKDIGWRAIEREQN"
     gene            complement(28371..29960)
                     /gene="purH"
                     /locus_tag="IRB70_003073"
     CDS             complement(28371..29960)
                     /gene="purH"
                     /locus_tag="IRB70_003073"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBC0632957.1"
                     /translation="MQQRRPVRRALLSVSDKAGIVEFAQALSARGVELLSTGGTARLL
                     AEKGLPVTEVSDYTGFPEMMDGRVKTLHPKVHGGILGRRGQDDAIMEEHQIQPIDMVV
                     VNLYPFAQTVAREGCSLEDAVENIDIGGPTMVRSAAKNHKDVAIVVKSSDYDAIIKEI
                     DANEGSLTLETRFDLAIKAFEHTAAYDSMIANYFGSMVPAYHGESKEAAGRFPRTLNL
                     NFIKKQDMRYGENSHQQAAFYIEENVKEASVATATQVQGKALSYNNIADTDAALECVK
                     EFAEPACVIVKHANPCGVAIGNSILDAYDRAYKTDPTSAFGGIIAFNRELDAETAQAI
                     ISRQFVEVIIAPSASEEALKITAAKQNVRVLTCGQWGERVPGLDFKRVNGGLLVQDRD
                     LGMVGAEELRVVTKRQPSEQELRDALFCWKVAKFVKSNAIVYAKNNMTIGIGAGQMSR
                     VYSAKIAGIKAADEGLEVKGSSMASDAFFPFRDGIDAAAAAGVTCVIQPGGSIRDDEV
                     IAAADEHGIAMLFTDMRHFRH"
BASE COUNT         7135 a         7898 c         8367 g         7021 t
ORIGIN      
        1 ctggaactgg ctggcttcct ggattcttac attccggaac cagagcgtgc gattgacaag
       61 ccgttcctgc tgccgatcga agacgtattc tccatctccg gtcgtggtac cgttgttacc
      121 ggtcgtgtag aacgcggtat catcaaagtt ggtgaagaag ttgaaatcgt tggtatcaaa
      181 gagactcaga agtctacctg tactggcgtt gaaatgttcc gcaaactgct ggacgaaggc
      241 cgtgctggtg agaacgtagg tgttctgctg cgtggtatca aacgtgaaga aatcgaacgt
      301 ggtcaggtac tggctaagcc gggcaccatc aagccgcaca ccaagttcga atctgaagtg
      361 tacattctgt ccaaagatga aggcggccgt catactccgt tcttcaaagg ctaccgtccg
      421 cagttctact tccgtactac tgacgtgact ggtaccatcg aactgccgga aggcgtagag
      481 atggtaatgc cgggcgacaa catcaaaatg gttgttaccc tgatccaccc gatcgcgatg
      541 gacgacggtc tgcgtttcgc aatccgtgaa ggcggccgta ccgttggcgc gggcgttgta
      601 gcaaaagttc tgagctaatt gccgataaca tttgacgcaa tgcgcactaa aagggcatca
      661 tttgatgccc tttttgcacg ctttcgtacc agaacctggc tcatcagtga ttttctttgt
      721 cataatcatt gctgagacag gctctgttga gggcgtataa tccgaaaagc taatacgcgt
      781 ttcgatttgg tttgcctcgc gatcgcgggg tgaaaatgtt tgtagaaaac ttctgacagg
      841 ttggtttatg agtgcgaata ccgaagctca aggaagcggg cgcggcctgg aagcgatgaa
      901 gtgggtcgtt gtggtggcat tgctcctggt ggcgattgtc ggcaactatc tttatcgcga
      961 cattatgctg ccgctgcgtg cgctggccgt agtaattctg attgctgcag cgggtggtgt
     1021 cgcgctgtta acgacaaaag gtaaagctac cgttgctttt gcccgtgaag cgcgtaccga
     1081 agtccgtaag gtcatttggc cgactcgcca ggaaacattg cacaccacgc tgattgtggc
     1141 tgcggttacc gcagtaatgt cactgatcct gtggggactg gatggtattc tggttcgcct
     1201 ggtatccttt atcactggcc tgaggttctg agatgtctga agctcctaaa aagcgctggt
     1261 acgtcgttca ggcgttttcc ggttttgaag gccgcgtagc aacgtcgctg cgtgagcata
     1321 tcaaattaca caacatggaa gatttgtttg gtgaagtcat ggtaccaacc gaagaagtgg
     1381 ttgaaatccg tggcggtcag cgtcgcaaaa gcgaacgtaa attcttccct ggctacgtcc
     1441 tcgttcagat ggtgatgaac gacgcgagct ggcacctggt gcgcagcgta ccgcgtgtga
     1501 tgggcttcat cggcggtact tccgatcgtc ctgcaccaat cagcgataaa gaagtcgatg
     1561 cgattatgaa ccgcctgcag caggttggtg ataagccgcg tccgaaaacg ctgtttgaac
     1621 cgggtgaaat ggtccgtgtt aatgatggtc cgttcgctga cttcaacggt gttgttgaag
     1681 aagtggatta cgagaaatct cgtctgaaag tgtctgtttc tatcttcggt cgtgcgaccc
     1741 cggtagagct ggacttcagc caggttgaaa aagcctaacc cagcgatcaa aaaagcggcg
     1801 atttaatcgt tgcacaaggc gcgagattgg aatacaattt cgcgcctttt gtttttatgg
     1861 gccttgcccg taaaacgatt ttttatatca cggggagcct ctcagaggcg ttattaccca
     1921 acttgaggaa tttataatgg ctaagaaagt acaagcctat gtcaagctgc aggttgcagc
     1981 tggtatggct aacccgagtc cgccagtagg tccggctctg ggtcagcagg gcgtaaacat
     2041 catggaattc tgcaaagcgt tcaacgcaaa aactgattcc atcgaaaaag gtctgccgat
     2101 tccggtagta atcaccgttt acgctgaccg ttctttcact ttcgttacca agactccgcc
     2161 agcagcagtt ctgctgaaaa aagcggctgg tatcaagtct ggttccggta agccgaacaa
     2221 agacaaagtg ggtaaaattt cccgcgctca gctgcaggaa atcgcgcaga ccaaagctgc
     2281 cgacatgact ggtgccgaca ttgaagcgat gactcgctcc atcgaaggta ctgcacgttc
     2341 catgggcctg gtagtggagg actaagaaat ggctaaactg accaagcgca tgcgtgttat
     2401 ccgcgagaaa gttgatgcaa ccaaacagta cgacatcaac gaagctatcg ctctgctgaa
     2461 agaactggcg actgctaaat tcgtagaaag cgtggacgta gctgttaacc tcggcatcga
     2521 cgctcgtaaa tctgaccaga acgtacgtgg tgcaactgta ctgccgcacg gtactggccg
     2581 ttccgttcgc gtagccgtat ttacccaagg tgcaaacgct gaagctgcta aagctgcagg
     2641 tgctgaactg gtaggtatgg aagatctggc tgaccagatc aagaaaggcg aaatgaactt
     2701 tgacgttgtt attgcttctc cggatgcaat gcgcgttgtt ggccagctgg gccaggttct
     2761 gggtccgcgc ggcctgatgc caaacccgaa agtgggtact gtaacgccga acgttgctga
     2821 agcggttaaa aacgctaaag ctggccaggt tcgttaccgt aacgacaaaa acggcatcat
     2881 ccacaccacc atcggtaaag tggactttga cgctgacaaa ctgaaagaaa acctggaagc
     2941 tctgctggtt gcgctgaaaa aagcaaaacc gactcaggcg aaaggcgtgt acatcaagaa
     3001 agttagcatc tccaccacca tgggtgcagg tgttgcagtt gaccaggctg gcctgagcgc
     3061 ttctgtaaac taatgccttt acgtgggcgg tgattttgtc tacaatctta cccccacgta
     3121 tgctaacgaa agttagcagc taaaaagatt tgttcgttgg agcctggcct atccaggcct
     3181 ccgtcgaaga ccgcaggagt ttcgcaagaa acttaatccc ctgcgtagac ggtgacagaa
     3241 cgctaagatt attcttttat attctggctt gtttctgctc accgtaatta agacgctctc
     3301 tccgtttgga ggagtgaagt gagttccaga gattttctct ggcaaacatc caggagcaaa
     3361 gctaatggct ttaaatcttc aagacaaaca agcgattgtt gctgaagtca gcgaagtagc
     3421 caaaggcgcg ctgtctgcag tagttgcgga ttcccgtggc gtaactgtag ataaaatgac
     3481 tgaactgcgt aaagcaggtc gcgaagctgg cgtatacatg cgtgttgttc gtaacaccct
     3541 gctgcgccgt gctgttgaag gtactccgtt cgagtgcctg aaagacgcgt ttgttggtcc
     3601 gaccctgatt gcatactcta tggaacaccc gggcgctgct gctcgtctgt tcaaagagtt
     3661 cgcgaaagcg aatgcaaaat ttgaggtcaa agccgctgcc tttgaaggtg agctgatccc
     3721 ggcgtctcag atcgaccgcc tggcaactct gccgacctac gaagaagcaa ttgcacgcct
     3781 gatggcaacc atgaaagaag cttcggctgg caaactggtt cgtactctgg ctgctgtacg
     3841 cgatgcgaaa gaagctgctt aatcgcagtt atctttttaa cgcattcgct tacgtataaa
     3901 cttattctga tattcaggaa caatttaaat gtctatcact aaagatcaaa tcattgaagc
     3961 agttgcagct atgtctgtaa tggacgttgt agaactgatc tctgcaatgg aagaaaaatt
     4021 cggtgtttcc gctgctgctg ctgtagctgt agctgctggc ccggttgaag ctgctgaaga
     4081 aaaaactgaa ttcgacgtaa ttctgaaagc tgctggcgct aacaaagttg ctgttatcaa
     4141 agcagtacgt ggcgcaactg gcctgggtct gaaagaagct aaagacctgg tagaatctgc
     4201 accggctgct ctgaaagaag gcgtgagcaa agacgacgca gaagcactga aaaaagctct
     4261 ggaagaagct ggcgctgaag ttgaagttaa ataagccaac ccttccggtt gcagcctgag
     4321 aaatcaggct gatggctggt gactttttag tcaccagcct ttttgcgctg taaggcgcca
     4381 gtagcgtttc acactgtttg actactgctg tgcctttcaa tgcttgtttc tatcgacgac
     4441 ttaatatact gcgacaggac gtccgttctg tgtaaatcgc aatgaaatgg tttaagcgtg
     4501 atagcaacag gcattgcgga aagtgttcca ttttccggtc aacaaaatag tgttgcacaa
     4561 actgtccgct caatggacag atgggtcgac ttgtcagcga gctgaggaac cctatggttt
     4621 actcctatac cgagaaaaaa cgtattcgta aggattttgg taaacgtcca caagttctgg
     4681 atgtacctta tctcctttct atccagcttg actcgtttca gaaatttatc gagcaagatc
     4741 ctgaagggca gtatggtctg gaagctgctt tccgttccgt attcccgatt cagagctaca
     4801 gcggtaattc cgagctgcaa tacgtcagct accgccttgg cgaaccggtg tttgacgtcc
     4861 aggaatgtca aatccgtggc gtgacctatt ccgcaccgct gcgcgttaaa ctgcgtctgg
     4921 tgatctatga gcgcgaagcg ccggaaggca ccgtaaaaga cattaaagaa caagaagtct
     4981 acatgggcga aattccgctc atgacagaca acggtacctt tgttatcaac ggtactgagc
     5041 gtgttatcgt ttcccagctg caccgtagtc cgggcgtctt ctttgactcc gacaaaggta
     5101 aaacccactc ttcgggtaaa gtgctgtata acgcgcgcat tatcccttac cgtggttcct
     5161 ggctggactt cgaattcgat ccgaaggaca acctgttcgt acgtatcgac cgtcgccgta
     5221 aactgcctgc gaccatcatt ctgcgcgccc tgaactacac cacagagcag atcctcgacc
     5281 tgttctttga aaaagttatc tttgaaatcc gtgataacaa gctgcagatg gaactggtgc
     5341 cggaacgcct gcgtggtgaa accgcatctt ttgacatcga agctaacggt aaagtgtacg
     5401 tagaaaaagg ccgccgtatc actgcgcgcc acattcgcca gctggaaaaa gacgacgtca
     5461 aactgatcga agtcccggtt gagtacatcg caggtaaagt ggttgctaaa gactatattg
     5521 atgagtctac cggcgagctg atctgcgcag cgaacatgga gctgagcctg gatctgctgg
     5581 ctaagctgag ccagtctggt cacaagcgta tcgaaacgct gttcaccaac gatctggatc
     5641 acggcccata tatctctgaa accttacgtg tcgacccaac taacgaccgt ctgagcgcac
     5701 tggtagaaat ctaccgtatg atgcgccctg gcgagccgcc gactcgtgaa gcagctgaaa
     5761 gcctgttcga gaacctgttc ttctccgaag accgttatga cttgtctgcg gttggtcgta
     5821 tgaagttcaa ccgttctctg ctgcgcgaag aaatcgaagg ttccggtatc ctgagcaaag
     5881 acgacatcat tgatgttatg aaaaagctca ttgatatccg taacggtaaa ggcgaagtcg
     5941 atgatatcga ccacctcggc aaccgtcgta tccgttccgt tggcgaaatg gcggaaaacc
     6001 agttccgcgt tggcctggta cgtgtagagc gtgcggtgaa agagcgtctg tctctgggcg
     6061 atctggatac cctgatgcct caggatatga tcaacgccaa gccgatttct gcagcagtga
     6121 aagagttctt cggttccagc cagctgtctc agtttatgga ccagaacaac ccgctgtctg
     6181 agattacgca caaacgtcgt atctccgcac tcggcccagg tggtctgacc cgtgaacgtg
     6241 caggcttcga agttcgagac gtacacccga ctcactacgg tcgcgtatgt ccaatcgaaa
     6301 cccctgaagg tccgaacatc ggtctgatca actctctgtc cgtgtacgca cagactaacg
     6361 aatacggctt ccttgagact ccgtatcgta aagtgaccga cggtgttgta actgacgaaa
     6421 ttcactacct gtctgctatc gaagaaggca actacgttat cgcccaggcg aactccaacc
     6481 tggatgaaga aggccacttc gtagaagacc tggtaacttg ccgtagcaaa ggcgaatcca
     6541 gcttgttcag ccgcgaccag gttgactaca tggacgtatc cacccagcag gtggtatccg
     6601 tcggtgcgtc cctgatcccg ttcctggaac acgatgacgc caaccgtgca ttgatgggtg
     6661 cgaacatgca acgtcaggcc gttccgactc tgcgtgctga taagccgctg gttggtacgg
     6721 gtatggaacg tgctgttgcc gttgactccg gtgtaactgc ggttgctaaa cgtggtggtg
     6781 tcgttcagta cgtggatgct tcccgtatcg ttatcaaagt taacgaagat gagatgtatc
     6841 cgggtgaagc aggtatcgac atctacaacc tgaccaagta cacccgttct aaccagaaca
     6901 cctgtatcaa ccagatgccg tgtgtgtctc tgggtgaacc ggttgaacgt ggcgacgtgc
     6961 tggcagacgg tccgtccacc gacctcggtg aactggcgct tggtcagaac atgcgcgtag
     7021 cgttcatgcc gtggaatggt tacaacttcg aagactccat cctcgtatcc gagcgtgttg
     7081 ttcaggaaga ccgtttcacc accatccaca ttcaggaact ggcgtgtgtg tcccgtgaca
     7141 ccaagctggg gccggaagag atcaccgctg acatcccgaa cgtgggtgaa gctgctctct
     7201 ccaaactgga tgaatccggt atcgtttaca ttggtgcgga agtgaccggt ggcgacattc
     7261 tggttggtaa ggtaacgccg aaaggtgaaa ctcagctgac cccagaagaa aaactgctgc
     7321 gtgcgatctt cggtgagaaa gcgtctgacg ttaaagactc ttctctgcgc gtaccaaacg
     7381 gtgtatccgg tacggttatc gacgttcagg tctttactcg cgatggcgta gaaaaagaca
     7441 aacgtgcgct ggaaatcgaa gaaatgcagc tcaaacaggc gaagaaagac ctgtctgaag
     7501 aactgcaaat cctcgaagcg ggtctgttca gccgtatccg tgctgtgctg gtagctggtg
     7561 gcgttgaagc tgagaagctc gacaaactgc cgcgcgatcg ctggctggag ctgggcctga
     7621 ccgacgaaga gaaacaaaat cagctggaac agctggctga gcagtatgac gaactgaaac
     7681 acgagttcga gaagaaactc gaagcgaaac gccgcaaaat cacccagggc gacgatctgg
     7741 caccgggcgt gctgaagatt gttaaggtat atctggcggt taaacgccgt atccagcctg
     7801 gtgacaagat ggcaggtcgt catggtaaca agggtgtaat ttctaagatc aacccgatcg
     7861 aagatatgcc ttacgatgaa aacggtacgc cggtagacat cgtactgaac ccgctgggcg
     7921 taccgtctcg tatgaacatt ggtcagatcc tcgaaaccca cctgggtatg gctgcgaaag
     7981 gtatcggcga caagatcaac gccatgctga aacagcagca agaagtcgcg aaactgcgcg
     8041 aattcatcca gcgtgcgtac gatctgggcg ctgatgttcg tcagaaagtt gacctgagta
     8101 ccttcagcga tgaagaagtt atgcgtctgg ctgaaaacct gcgcaaaggt atgccaatcg
     8161 caacgccggt gttcgacggt gcgaaagaag cagaaattaa agagctgctg aaacttggcg
     8221 acctgccgac ttctggtcag atccgcctgt acgacggtcg cactggtgaa cagttcgagc
     8281 gtccggtaac cgttggttac atgtacatgc tgaaactgaa ccacctggtc gacgacaaga
     8341 tgcacgcgcg ttccaccggt tcttacagcc tggttactca gcagccgctg ggtggtaagg
     8401 cacagttcgg tggtcagcgt ttcggggaga tggaagtgtg ggcgctggaa gcatacggcg
     8461 cagcatacac cctgcaggaa atgctcaccg ttaagtctga tgacgtgaac ggtcgtacta
     8521 agatgtataa aaacatcgtg gacggcaacc atcagatgga gccgggcatg ccagaatcct
     8581 tcaacgtatt gttgaaagag attcgttcgc tgggtatcaa catcgaactg gaagacgagt
     8641 aattctcgct caaacaggtc actgctgtcg gggtaaaacc cggcagcgga ttgtgctaac
     8701 tccgacggga gcaaatccgt gaaagattta ttaaagtttc tgaaagcgca gactaaaacc
     8761 gaagagtttg atgcgatcaa aattgctctg gcttcgccag acatgatccg ttcatggtct
     8821 ttcggtgaag ttaaaaagcc ggaaaccatc aactaccgta cgttcaaacc agaacgtgac
     8881 ggccttttct gcgcccgtat ctttgggccg gtaaaagatt acgagtgcct gtgcggtaag
     8941 tacaagcgcc tgaaacaccg tggcgtcatc tgtgagaagt gcggcgttga agtgacccag
     9001 actaaagtac gccgtgagcg tatgggccac atcgaactgg cttccccgac tgcgcacatc
     9061 tggttcctga aatcgctgcc gtcccgtatc ggcctgctgc tcgatatgcc gctgcgcgat
     9121 atcgaacgcg tactgtactt cgaatcctat gtggttatcg aaggcggtat gaccaacctg
     9181 gaacgtcagc agatcctgac tgaagagcag tatctggacg cgctggaaga gttcggtgac
     9241 gaattcgacg cgaagatggg tgcggaagca atccaggctc tactgaagag catggatctg
     9301 gagcaagagt gcgaacagct gcgtgaagag ctgaacgaaa ccaactccga aaccaagcgt
     9361 aaaaagctga ccaagcgtat caaactgctg gaagcgttcg ttcagtctgg taacaaacca
     9421 gagtggatga tcctgaccgt tctgccggta ctgccgccag atctgcgtcc gctggttccg
     9481 ctggatggtg gtcgtttcgc gacttctgac ctgaacgatc tgtatcgtcg cgtcattaac
     9541 cgtaacaacc gtctgaaacg tctgctggat ctggctgcgc cggacatcat cgtacgtaac
     9601 gaaaaacgta tgctgcagga agcggtagac gccctgctgg ataacggtcg tcgcggtcgt
     9661 gcaatcaccg gttctaacaa gcgtcctctg aaatctttgg ccgacatgat caaaggtaaa
     9721 cagggtcgtt tccgtcagaa cctgctcggt aagcgtgttg actactccgg tcgttctgta
     9781 atcaccgtag gtccatacct gcgtctgcat cagtgcggtc tgccgaagaa aatggcgctg
     9841 gagctgttca aaccgttcat ctacggcaag ctggaactgc gtggtcttgc taccaccatc
     9901 aaagctgcga agaaaatggt tgagcgcgaa gaagctgtcg tttgggatat cctggacgaa
     9961 gttatccgcg aacacccggt actgctgaac cgtgcaccga ctctgcaccg tctgggtatc
    10021 caggcatttg aaccggtact gatcgaaggt aaagctatcc agctgcaccc gctggtttgt
    10081 gcggcatata acgccgactt cgatggtgac cagatggctg ttcacgtacc gctgacgctg
    10141 gaagcccagc tcgaagcgcg tgcgctgatg atgtctacca acaacatcct gtccccggcg
    10201 aacggcgaac caatcatcgt tccgtctcag gacgttgtac tgggtctgta ctacatgacc
    10261 cgcgactgtg ttaacgccaa aggcgaaggc atggtgctga ctggcccgaa agaagcagaa
    10321 cgtctgtatc gctctggtct ggcttctctg catgcgcgcg ttaaagtgcg tatcaccgag
    10381 tatgaaaaag atgctaacgg tgaattagtg gcgaaaacca gcctgaaaga cacgactgtt
    10441 ggccgtgcca ttctgtggat gattgtaccg aaaggtctgc cttacaccat cgtcaaccag
    10501 gcgctgggta aaaaagcaat ctccaaaatg ctgaacacct gctaccgcat tctcggtctg
    10561 aaaccgaccg ttatttttgc ggaccagatc atgtataccg gctttgcata tgcagcgcgt
    10621 tctggtgcat ctgttggtat cgatgacatg gtcatcccgg agaagaaaca cgaaatcatc
    10681 tccgaggcag aagcagaagt tgctgaaatt caggagcagt tccagtctgg tctggtaact
    10741 gcgggcgaac gctacaacaa agttatcgat atctgggctg cggcgaacga tcgtgtatcc
    10801 aaagcgatga tggataacct gcaaactgaa accgttatta accgtgacgg tcaggaagag
    10861 aagcaggttt ccttcaacag catctacatg atggccgact ccggtgcgcg tggttctgcg
    10921 gcacagattc gtcagcttgc tggtatgcgt ggtctgatgg cgaagccgga tggctccatc
    10981 atcgaaacgc caatcaccgc gaacttccgt gaaggtctga acgtactcca gtacttcatc
    11041 tccacccacg gtgctcgtaa aggtctggcg gataccgcac tgaaaactgc gaactccggt
    11101 tacctgactc gtcgtctggt tgacgtggcg caggacctgg tggttaccga agacgattgt
    11161 ggtacccatg aaggtatcat gatgactccg gttatcgaag gtggtgacgt taaagagccg
    11221 ctgcgcgatc gcgtactggg tcgtgtaact gctgaagacg ttctgaagcc gggtactgct
    11281 gatatcctcg ttccgcgcaa cacgctgctg cacgaacagt ggtgtgacct gctggaagag
    11341 aactctgtcg acgcggttaa agtacgttct gttgtatctt gtgacaccga ctttggtgta
    11401 tgtgcgcact gctacggtcg tgacctggcg cgtggccacc tcatcaacaa aggtgaagca
    11461 atcggtgtta tcgcggcaca gtccatcggt gaaccgggta cacagctgac catgcgtacg
    11521 ttccacatcg gtggtgcggc atctcgtgcg gctgctgaat ccagcatcca ggtgaaaaac
    11581 aaaggtagca tcaagctcag caacgtgaag tcggttgtga actccagcgg taaactggtt
    11641 atcacttccc gtaacaccga actgaaactg atcgacgaat tcggtcgtac caaagaaagc
    11701 tacaaagtac cttacggtgc ggtactggcg aaaggcgatg gcgaacaggt tgctggcggc
    11761 gaaaccgttg caaactggga cccgcacacc atgccggtta tcaccgaagt aagcggtttt
    11821 gtacgcttta ctgacatgat cgacggccag accattactc gtcagaccga cgaattgacc
    11881 ggtctgtctt cgctggtggt tctggattcc gcagaacgta ccgcaggtgg taaagatctg
    11941 cgtccggcac tgaaaatcgt tgatgctcag ggtaacgacg ttctgatccc gggtaccgat
    12001 atgcctgcgc agtacttcct gccgggtaaa gcgattgttc agctggaaga tggcgtacag
    12061 atcagctctg gtgacaccct ggcgcgtatt ccgcaggaat ccggcggtac caaggacatc
    12121 accggtggtc tgccgcgcgt tgcggacctg ttcgaagcac gtcgtccgaa agagccggca
    12181 atcctggctg aaatcagcgg tatcgtttcc ttcggtaaag aaaccaaagg taaacgtcgt
    12241 ctggttatca ccccggtaga cggtagcgat ccgtacgaag agatgattcc gaaatggcgt
    12301 cagctcaacg tgttcgaagg tgaacgtgta gaacgtggtg acgtaatttc cgacggtccg
    12361 gaagcgccgc acgacattct gcgtctgcgt ggtgttcatg ctgttactcg ttacatcgtt
    12421 aacgaagtac aggacgtata ccgtctgcag ggcgttaaga ttaacgataa acacatcgaa
    12481 gttatcgttc gtcagatgct gcgtaaagct accatcgtta atgcgggcag ctccgacttc
    12541 ctggaaggcg aacaggttga atactctcgc gtcaagatcg caaaccgcga actggaagcg
    12601 aacggcaaag tgggtgcaac ttactcccgc gatctgctgg gtatcaccaa agcgtctctg
    12661 gcaaccgagt ccttcatctc cgcggcatcg ttccaggaga ccactcgcgt gctgaccgaa
    12721 gcagccgttg cgggcaaacg cgacgaattg cgcggcctga aagagaacgt tatcgtgggt
    12781 cgtctgatcc cggcaggtac cggttacgcg taccaccagg atcgtatgcg tcgccgtgct
    12841 gcgggtgaag ctccggctgc accgcaggtg actgcagaag acgcatctgc cagcctggca
    12901 gaactgctga acgcaggtct gggcggttct gataacgagt aatcgttaat ccgcaaataa
    12961 cgtaaaaacc cgcttcggcg ggttttttta tgggtgttat tcagagggca aagtcttcac
    13021 gggaaatatt aagaaaggca gggcgaaacg aggaagaagc ttttcgccct ggacaacatt
    13081 cctgctgacg gcactaccat aaaaaaacac aacgctttca acaaccttgc gtttttcatc
    13141 ttccgtagcg gctcggaata aatttacgtt gttacattct gtttcatggc ctttgcgagg
    13201 cgcgtcccag atagctgtcc cagtctttcc ataccggctg caaaccctga gcagttaacg
    13261 cggcagcaac cgcttccggt ctgcgatcgt cgtgcggtga gaactgttcc agctcggggt
    13321 gattgtcggc atagccacct ggctgcgttt tcgaaaaagc gctgacgtta ttaattgcca
    13381 gcggaatcac gcgatcgcga aaccacggtg attcccgcgt ggagagtgac agttcaatct
    13441 ccggtgcaag cagtcggaag gcgcagatgg tttgcactaa ctggcgttca tccataatcg
    13501 acgcaggctc aatgccgcca gtacatggac gcaggcgtgg gaaggagaca gagtagcggc
    13561 tttgccagta atgctgttgc agccatagca aatgttctgc aaccatatag cagtcaacgc
    13621 gccagctgtc ggaaaggcca attagcgcgc cgaggcctat cttatcaatc cccgcacggc
    13681 ccagccgatc cggcgtttcc agccgccaga agaagtcctg ttttttgcct ttcagatgat
    13741 ggcgggcata agtcgcctcg tgatatgtct cctgataaac catcacgcca tcgagaccca
    13801 gctgttttag ctcggcatat tccgcctccg ccagcggttg cacttccatc tgtagtgaag
    13861 agaactgttc acgcagggca gggagatgac gacgaaagta atccatcccc actttcgcct
    13921 gatgttcacc agtgactaaa agcagatgtt caaagcccat ctcccgtata gcggcgcttt
    13981 ccctggcaat atccgcttca tccagtgttt tgcgcttgat gcgattgctc atggaaaatc
    14041 cgcagtacgt gcagtcgtta gcgcaaagat tggaaagata aagcgggacg tagaaactaa
    14101 ctgtgttgcc aaatcgctga cgggtcagac gctgcgctcg ctgggccagt ggttccagat
    14161 agccactggc ggcgggtgat agcaatgcca tcatgtcgtc gcgggtgagt tgcgaggcat
    14221 ttagcgcccg ctctacgtca gcagccgttt tgccgttgat acgcaggcgg atgtcgtccc
    14281 agtccagttg tcgccagcga tcgctgaagg ttttcatgca gatgcctcca gaaatccagt
    14341 cagcgggctg gtggcatgag caaaatgact gcggctgccc ggtccggact gacgtgccag
    14401 caggcctgct tctaccgcca gacgaaatgc cttcgccatg ttgacgggat cgtccgcgac
    14461 ggcaatcgcc gtattcacta acaccgcgtc ggcccccatt tccagcgcct gcgcggcatg
    14521 gctgggaacg ccgatgccag catcgacaac caccggaacc gtggcctgct ggataataat
    14581 ctccagcatg gcgcgggttt ccagtccctg attcgagcca atcggcgcgc cgagcggcat
    14641 caccgctgca cagccgactt cttccagacg tttacacaat accggatcgg ccccgcagta
    14701 aggcagcacg acaaatccct gttgtaccag cgtttcggcg gctttcaggg tttcgatggg
    14761 atcgggcaac agccagcggg cgtcagggtg aatctccaat tttagccagt ttgcgcctaa
    14821 cgcttcacgt gccagatggg cagcaaagat cgcttcttcc gcagttttcg ctccggaagt
    14881 attcggcagc agtgttacac ccgccgcgat aagtggttcg aggatagcgt cgttgtgctg
    14941 gcgcaagtcg acacgtttca tcgccagcgt caccagttgg ctgccggaag cgcgaataga
    15001 ctccaccatc agttgtgaag aggcgaattt tccggtgcca gtaaacagat gtgaatcaaa
    15061 cgttttgtcc gcaatatgta acatctcaac cccctgcaat aacctgaaaa agcaggatct
    15121 ggtcgccatc ctgcacgata tgttgcgccc actgctcacg cgggacgatt tgctgattaa
    15181 tcgccagagc cgcgcccgct tgtcgttggt cgagttgctc cagcagttcg tgaaccgttt
    15241 gcccggcggc gcactgcatc ggttgatcgt taaacaggat ctgcattgct tcctccgcat
    15301 accgggcaac cactggcgcg gcgcaaagcc aggctgcgcc actggctcga cttaccgtcg
    15361 aacagtcgga gttctcccgc aggcgtctct ataccgctta ataacttaat ggcttccagg
    15421 gcctgcaaag tgcccataac cccgaccacc gggccaacca cgcccgccgt gcggcagttg
    15481 cgttcaggct cctggttatc tggccacagg cagcggtaac acccctgctc ccagggcggc
    15541 gtcagtacca tcaactgacc gccaaatccg accgcgctgg cggtgataag cggtgtgttg
    15601 agtgccacgc aggcggcatt aatctcctgg cgagtcgcca tattgtcggt acagtcgagc
    15661 accacatcgg cttgtgcaac cgcatctttt aacgtctcac ccgttaatcg ttgttgtaat
    15721 gccatcagtt gaatgtcggg attcaactgt gtcagtcgct gatggctgac ctgtgatttc
    15781 gggcgatcga tatcttcagt ggtaaagagg atttgtcgtt gcagattgct taaatgcaca
    15841 tcgtcgtcat ctgccagtac cagcgtcccg acgccagccc ccgccaggta tagcgcagca
    15901 ggtgtaccca gcccgccaag accaataatc agcacctggc tgtcgagcag tttttgctgc
    15961 ccgtccagag cgatatcgtc gagcaggatt tggcggctat aacgcataaa gtcacggtca
    16021 ttcatcgcca gctcctgcaa tttccagcaa ctgtgccgtt gccaaacgcc agtctgcggc
    16081 ttgagtaatg gcgctgacga cggcgatact gccgacaccc gttgctatca cctcaggcgc
    16141 gcgcgccaga ctgataccgc caatcgccac ggtgggataa tccaccaggc gctcaacatg
    16201 tcgtgccagc tgttccagcc cctgcggtgc ggaaggcatc tgtttggttt gtgtcggaaa
    16261 cacatgtccc agcgcgatat aagaaggatg tgccgccagc gcgacgtcga tttccatatc
    16321 atcatgtgtc gaaacgccca gtcgcagacc tgccgcgcgg atggcgctga gatcggtggc
    16381 ttgcaaatct tcctgcccca aatggacgcc gtatgcttga tgcttgatcg ccagccgcca
    16441 gtaatcatta ataaacaatc gcgcgttata gcggcggccc agcgcaattg ccgccaccac
    16501 atcggcttct acctcttcat cgcgccgatc tttgatgcgt agctggagag tacgtacgcc
    16561 tgcatccaac agacgttcga tccactgtac gctgtcaacc accgggtaca gccctaaacg
    16621 aaagggtaca ggaggaaact caggctgata catcacgctt cctccttacg caggtagatt
    16681 tctccgcctc tggcgcggaa gttctccgac atatccgcca tccccacttc aatggtttgc
    16741 gcggcggcgt aatcacgtac ttcctggctg attttcatcg agcagaattt cggcccacac
    16801 atggagcaaa aatgggcgac tttgccggac tcttgcggca gggtttcatc gtgataagcg
    16861 cgggcggtaa acgggtcgag ggccagatta aactggtctt cccagcgaaa ttcgaagcgg
    16921 gctttcgaca tggcgttatc gcgaatttgt gcgcccggat gtcctttcgc caggtcggcg
    16981 gcgtgggcgg caatcttata ggtgataagc ccctgcttaa catcttcttt attaggtaga
    17041 cccagatgct cttttggcgt tacgtagcag agcatcgcgc agccaaacca gccaatcatc
    17101 gccgcgccaa tccccgacgt gaagtggtca taacccggag caatatcagt agttagcggc
    17161 ccgagggtat agaacggtgc ttcgtggcag tgctctaact cctcggtcat attgcggcgg
    17221 atcatctgca tcggtacatg cccaggacct tcaatcatca cctgtacgtc atattcccag
    17281 gcgattttgg tcagttcacc cagcgtatgc agctcggcaa attgcgcttc atcgttggcg
    17341 tcctgaacag aaccggggcg cagaccgtcg cccagcgaca gcgaaacgtc ataagcggca
    17401 cagatttcac aaatttcgcg gaagtgttga tagaggaaat tttcctgatg atgggagagg
    17461 caccatttcg ccataatcga accgccgcga gagacgatac cagtcaggcg tttcgcggtc
    17521 atcggcacat agcgcagcag tacgcccgca tggatagtga agtaatccac accttgctcg
    17581 gcttgttcca gcagcgtgtc gcggaacgct tcccagctaa gatcttcagc gatcccatta
    17641 accttctcca gcgcctggta gatcggcact gtaccaatcg gcaccgggct gttacgcaaa
    17701 atccattcgc gagtttcgtg aatatagcga ccggtggaaa gatccatcac tgtatccgcc
    17761 ccccagcgcg tagaccatac cagcttttcc acttcttctt cgatggaaga ggtgatcgcc
    17821 gagttgccga tattggcgtt aacttttacc aggaaattgc gaccaataat catcggctcc
    17881 gattccggat ggttgatgtt ggcggggata atggcacgtc cggcagcgac ttcatcacgg
    17941 acaaattccg cagtgatatt ttccggcaga cgtgcgccaa agctcattcc cggatgctgg
    18001 tggcgtaaaa cttcgctacg tatgcgctcg cggcccatat tctcgcggat ggcgatgaat
    18061 tccatttccg gtgtgatgat gccctggcgg gcgtagtgca gttgggtgac gcggcgtcct
    18121 gctttggcac gttttggcgt taataagccg ctaaaacgta gctcgtcgag gccatcatct
    18181 gccagccgcg ctttagtgta atcggaactg cgtacggtaa gttcttcggt atcgccgcgc
    18241 gcatcgatcc acggctggcg cagttttgcc agtccttgct gcacgtcaat ggcgatctgt
    18301 ggatcgccat acggaccgga ggtgtcgtag accggaatcg cttcgttttc ttcgtactgc
    18361 ggctgttctt tgctgccgcc aattagcgtc gggctaagct ggatctcacg catcggcacg
    18421 cgcacgccgg ggtgtgtgcc agtgatgtaa atgcgttttg agttgggaaa ggcggtgcct
    18481 tccagggtgt cgataaaatg ttgggcctgg gcgcgttgtt cgcggcgggt cagttttgtt
    18541 gcagacatag ctcattccaa aaagttaagg acgtggcttg tcagacgacg gatgaagcaa
    18601 gagacgatcg ccgcaaaggc gatgcgatag cagattaact cttgttccct tcgcaggtat
    18661 tagcctgatc aggttccgcg gatcccgaat aaacggtctc agccagttaa ggcactccga
    18721 caagaaatta gccccgcaaa cggggcgttg aatgtaaatt acgcgttaac agcgcagaac
    18781 tcaagcagga tgtttgacgc gggcggcgtc aagcaccagc agaatcagct tatcttccag
    18841 cacaaagcgc gcttccaggg cctcgccgat gtcagataaa acctgttgaa actcaaggta
    18901 attatcatga tcgatagcgg tttccaggct ggaatcgtag taatccataa tctgttgggt
    18961 attggcttcg agttgtggcc aaatcttcgc ggcgcgtgcg agttgcccat tgccttccag
    19021 tttatgaaga atgcgctcat aaatactgaa atgtccggca gacaagtaat cgaccaggct
    19081 ctgacaaaaa tcatcaaggg ctttttcgtt tagcctcatg tacgattctt tgccaggctt
    19141 aatgccaacc agattgtagt aagccacgag cagatgctta cgtacatgta gccagcgatc
    19201 aaccagtttg ttacttcctc tgacgcgctc cgtcaggtta tcgagctggt taagcatgat
    19261 tgactccgca agtttgtatt caaaaactgc tcagtgagaa atgtaaaaac catgttaaac
    19321 atgccagtga tgcaaaggta gtgcaagagt tatggatcgt ataattgaaa aattagatca
    19381 cggctggtgg gtcgtcagcc atgaacaaaa attatggttg ccgaagggag aattgccata
    19441 tggcgaagcg gcaaatttcg atcttgtggg tcagcgcgca ctacaaatcg gcgaatggca
    19501 gggggaacct gtttggttag tacaacagca gcggcgtcac gatatggggt cggtacgtca
    19561 ggtcattgat ctcgatgttg ggctgtttca actggccgga cgaggcgtac aactggcgga
    19621 gttttaccga tcgcataaat actgtggtta ctgcgggcat gaaatgtatc caagcaaaac
    19681 cgaatgggcg atgctgtgca accattgccg tgagcgttac tacccgcaaa tcgccccctg
    19741 cattattgtt gccatccgtc gcgatgattc gatcctcctc gcccagcata cccgccatcg
    19801 taacggtgtc catacggtac ttgccggatt cgtcgaagtg ggcgaaaccc tcgagcaggc
    19861 tgtcgcgcgg gaagtgatgg aagagagcgg aattaaagtt aaaaacttgc gttacgtgac
    19921 ttcccagccg tggccgtttc ctcagtcttt aatgaccgcg tttatggcgg aatatgacag
    19981 cggcgagatc gtgatcgacc cgaaagaatt gcttgaggcg aactggtatc gctatgacga
    20041 tttgccgtta ctcccgccgc ccggcaccgt agcgcgccgt ctgatagaag atacagtggc
    20101 gatgtgtcgg gcagagtatg agtgatgata cactgaccgc ctgacgcact aaggaacagc
    20161 caaaatgacc gaacttaaaa acgatcgtta tctgcgggcg ctgctgcgcc agcccgttga
    20221 tgtcactcca gtatggatga tgcgccaggc gggtcgctat ctaccggaat ataaagccac
    20281 gcgcgcccag gcgggcgatt ttatgtcgct gtgcaaaaat gccgagctgg cgtgcgaagt
    20341 gactttgcaa ccgctgcgtc gctatccgct ggatgcggcg atcctctttt ccgatatcct
    20401 caccgtgcca gacgcgatgg gtttagggct ctattttgaa gccggagaag gtccgcgttt
    20461 tacctcgcca gtcacctgca aagccgacgt cgataaactg ccaattccgg acccggaaga
    20521 tgagctgggt tacgtgatga acgcggtgcg taccattcgt cgcgaactga aaggcgaagt
    20581 gccgctgatt ggtttttccg gcagcccgtg gacgctggcg acctacatgg tggaaggcgg
    20641 cagcagcaaa gcgttcaccg tgatcaaaaa aatgatgtat gccgatccac aggcgctgca
    20701 cgcgctactc gataaactgg cgaaaagcgt cactttgtat ctgaatgcgc agattaaagc
    20761 cggtgctcag gcagtgatga ttttcgacac ctggggcggc gtgcttaccg ggcgcgatta
    20821 tcaacagttc tcgctctatt acatgcataa aattgttgat ggtttactgc gtgaaaacga
    20881 cggtcgccgc gtgccagtca cgctgtttac caaaggtggc ggacagtggc tggaagcgat
    20941 ggcagaaacc ggttgcgatg cgctgggcct cgactggaca acggacatcg ccgatgcgcg
    21001 ccgccgcgtc ggcaataaag tcgcgttgca gggcaatatg gatccgtcga tgctgtatgc
    21061 gccgcctgcc cgcattgaag aagaagtggc gtctatactt gccggtttcg gtcacggcga
    21121 aggtcatgtc tttaaccttg gtcacggcat tcatcaggat gtgccgccag aacatgctgg
    21181 cgtgtttgtg gaggcagtgc atcgcctgtc tgcgccttat catctgtaag gagtggttat
    21241 ggatctcgcg tcattacgcg ctcaacaaat cgaactggct tcttctgtga tccgcgagga
    21301 tcgactcgat aaagatccac cggatctgat cgccggagcc gatgtcggat ttgagcaggg
    21361 cggagaagtg acgcgagcgg cgatggtgct gctgaaatac ccctcgcttg agctggtgga
    21421 gtataaagtg gcccgcatcg ccaccaccat gccttacatt ccaggttttc tctccttccg
    21481 cgaatatcct gcgctgctgg cagcgtggga gatgctgtca caaaagccgg atttagtgtt
    21541 tgtcgatggt cacgggatct cgcatcctcg ccgtcttggt gtcgccagcc attttggctt
    21601 attggtggat gtgccaacga taggcgtggc gaaaaaacgg ctctgcggta aattcgaacc
    21661 gctctccagc gaaccgggcg cgctggcccc actgatggat aaaggcgagc agctggcctg
    21721 ggtctggcgc agcaaagcgc gctgtaaccc attgtttatc gctaccggcc atcgggtcag
    21781 cgtggacagc gcgctggcgt gggtacaacg ctgcatgaaa ggctatcgtc tgccggagcc
    21841 aacgcgctgg gcggacgcgg tggcctcgga acgtccggcg ttcgtgcgct atacagcaaa
    21901 tcagccctaa ttcaggtaaa ctgcggataa tttccgtatt tgagaactca acatgttaca
    21961 aaacccaatt catctgcgtc tggagcgcct ggaaagctgg cagcacgtca ctttcatggc
    22021 ttgcttatgc gaacgcatgt accccaatta cgccatgttc tgccagcaaa ccggttttgg
    22081 tgatgggcag atttaccgcc gcattctcga tctcatctgg gaaacgctga ccgtcaaaga
    22141 cgcaaaagta aatttcgaca gccaactgga gaaatttgaa gaagcgattc cttcagccga
    22201 cgatttcgat ctgtacggcg tttatccggc aatcgatgcc tgcgtggcgt taagtgaact
    22261 ggtccattcg cgtttgagtg gtgaaacgct cgaacacgcg gtggaagtga gtaagacctc
    22321 catcacgacc gttgcgatgc tggaaatgac tcaggctggt cgcgaaatga gcgatgaaga
    22381 gctcaaagaa aacccagctg tagagcaaga atgggacatt cagtgggaaa tattccgact
    22441 tttagctgag tgcgaagaac gcgatatcga gctgataaaa ggccttaggg cagacctgcg
    22501 tgaggcgggt gagagcaata ttggtataat ttttcagcaa taagaccaga aaacgtgatt
    22561 taacgcctga tttgtcgtac ctggagtctt ccctttcgcc ccccgtctgg tctacatttg
    22621 gggggcgaaa aaaagtggct atcggtgcgt gtatgcagga gagtgctatt ctggcatttc
    22681 cgtcgcactc gatgcttagc aagcgataaa cacattgtaa ggataactta tgaacaagac
    22741 tcaactgatt gatgtaattg cagagaaagc agaactgtcc aaaacccagg ctaaagctgc
    22801 tctggagtcc actctggctg caattactga gtctctgaaa gaaggcgatg ctgtacaact
    22861 ggttggtttc ggtaccttca aagtgaacca ccgcgctgag cgtactggcc gcaacccgca
    22921 gaccggtaaa gaaatcaaaa ttgccgcagc taacgtaccg gcatttgttt ctggcaaggc
    22981 actgaaagac gcagttaagt aagattgcgt ggcagtgaac agttttaacg aaggggtggt
    23041 ttcacccctt ttgtctttct ggcgtcgatc attgatgctg gcaggcgctc tgtttctcac
    23101 tgcctgtagt cacaactctt cacttcctcc ctttaccgcc agtggatttg ctgaagacca
    23161 gggcgcggta cgcatctggc gaaaagacag cggcgataat gtgcatctgc ttgccgtgtt
    23221 tagcccgtgg cgcagtggcg ataccaccac gcgagagtat cgctggcagg gcgataacct
    23281 cacgctcatc aatatcaatg tttacagcaa accgccggtg aatattcgcg cgcgttttga
    23341 cgatcgcggc gatctgagct ttatgcaacg tgaatccgat ggggaaaagc agcagctttc
    23401 taacgaccaa atcgatttat accgttatcg tgctgatcag atccgccaga ttagcgatgc
    23461 cttacgtcag gggagagtcg tgctgcgcca ggggcgctgg catgcgatgg aacagaccgt
    23521 gaccacctgc gaagggcaaa ccattaaacc tgatttagat tcgcaggcga tagcgcatat
    23581 cgagcgccgc cagagccgct cttctgttga tgtcagcgtg gcatggctgg aagcgcccga
    23641 aggttcgcaa ttactgttgg tggcaaactc tgatttctgt cgctggcaac ccaacgagaa
    23701 aacgttctga tttaccagtg gcccataccc atatgaccgc caccaccgca gccgccgtag
    23761 cccatgccca ttccggctcc gcgcggaata cccgcttcag ccatcgcaat atctcgtttc
    23821 acccgtaact catctaacga ctgacgcaaa ttctccatct ctttggcgac cgcgttaatt
    23881 ttgctgctat ccggtgggtt cgcggctaac agggcattgt attcataacg cttcgtcacc
    23941 agttgctgtt gcagtgcgct gctttgagcg taaaagtcat tatggatttt ctgccacgct
    24001 gtctgttgtt cgctggtcaa aggcgcggca ttttgctgcc acataccatg tccgccgtga
    24061 gcaaatgccg atgtcgatcc catcgccatt gctgaaagcg ccatcattac cagggcaatt
    24121 ttcgtgttcc gtttcatggt taatcctcca gtggttgtct tacttcgggt attgcatctt
    24181 ccgtgccaac ggcgaaacgc tgatatgacg ggtaatctgg catgataaac gagtaaaaat
    24241 gactcgcctg ctgcgggtag cgagtcattt ttactcattg aaacttaagc ctttgtgtta
    24301 cagcgcaggg taagcgctga taaaagatgg catgatttct gccgtcagaa agggatgagc
    24361 aggcaaagaa gaagatgcgt tttatgcaac gttctaaaga ttccttagct aaatggttaa
    24421 gcgcgatcct ccccgtggtc attgttgggc tggtggggct gtttgcggtg acagtgattc
    24481 gcgattatgg gcgcgagact gccgccgcca gacaaacgct gctggaaaaa ggcagtgtac
    24541 ttattcgcgc tcttgaatcc ggctcgcgcg tcggtatggg gatgcgcatg catcatgcgc
    24601 agcagcaggc cttactggaa gaaatggccg ggcagcctgg agtacgttgg tttgcggtca
    24661 cggatgaaca aggaacaatc gtgatgcata gcaactccgg catggtggga aaacagcttt
    24721 attccccgca ggaaatgcag cagttacatc cgggagatga agaagcgtgg cggcggatcg
    24781 atagcgcaga cggcgagcct gttctggaaa tttatcgcca gtttcaaccg atgtttgctg
    24841 ctggaatgca ccggatgcgc catatgcagc aatatgccgc gacaccacaa gcaattttca
    24901 ttgctttcga cgccagtaac attgtgagtg ccgaagatcg tgagcagaga aataccctga
    24961 ttatcctctt cgccctggcg acggtcttgc tggcaagcgt gttgtcattc ttctggtatc
    25021 gtcgctatct gcgctcgcgc cagttgttgc aggatgaaat gaagcgcaaa gagaagctgg
    25081 tggcgctggg gcatcttgcg gcaggtgttg cccacgaaat ccgtaaccca ctttcctcga
    25141 ttaaaggact ggcgaaatac tttgccgaac gcgcgccagc agggggagaa gcgcatcaac
    25201 tggcgcaggt gatggcgaaa gaagccgacc gtttaaaccg cgtggtaagc gagttgctgg
    25261 aactggttaa gccaacgcat ctggctttgc aggcggtgga tctcaacacg ctgattaacc
    25321 actcattaca gctggtaagc caggatgcaa acagccggga gatccagtta cgctttaccg
    25381 ccaacgacac attaccggaa attcaggccg atccggacag gctgactcag gtcctgttga
    25441 atctctatct caatgccatt caggctattg gtcagcatgg cgtgattagc gttgtggcaa
    25501 atgaaagcgg agcgggcgtg aaaatcagcg ttaccgacag cggtaaggga attgcggcag
    25561 atcagcttga agccatcttc accccgtact tcaccaccaa agccgaaggt accggactgg
    25621 ggctggcggt cgtgcataat attgttgaac aacacggtgg tacaattcag gtcgcaagcc
    25681 aggagggaaa aggcgcaacg ttcacccttt ggcttccggt caatattacg cgtaaggacc
    25741 cacaaggatg acgcacgata atatcgatat tctggtggtg gatgatgaca ttagccactg
    25801 cactattttg caggctttgc tgcgcggctg gggctataac gtggcgcttg cgaacagcgg
    25861 gcgacaggcg ctggagcagg tgcgggaaca ggtttttgat cttgtgcttt gcgatgtgcg
    25921 aatggcagag atggacggca tcgccacgct caaagagatc aaagcgttaa atccggcaat
    25981 tccggtactg attatgaccg cgtactccag cgtcgagacg gcggtagagg cgttgaaaac
    26041 cggggcgctg gattatctca tcaagccgct ggatttcgat aacctgcagg cgacgctgga
    26101 aaaggcgctc gcacatacgc acagtgttga cgctgaaacg cctgcggtgt ctgccagcca
    26161 gttcagtatg gtcggtaaaa gcccggcgat gcaacacctg ctcagtgaaa tcgccctcgt
    26221 cgcgccatcg gaagccacgg tgctgatcca cggcgattcc ggcaccggta aagagctggt
    26281 cgccagggcg attcacgcca gtagcgcacg tagcgaaaaa ccgctggtaa cgctcaactg
    26341 cgcggcgctc aacgaatcct tgctggagtc tgaattgttc ggtcacgaaa aaggggcgtt
    26401 taccggggcc gacaaacgcc gggaagggcg ctttgttgag gcggacggcg gcacgttgtt
    26461 tctcgatgaa attggcgata tctcgccgat gatgcaggtg cgtctgctac gtgcgattca
    26521 ggagcgcgaa gttcagcgtg tcggtagcaa ccagactatt tcggttgatg tccggctgat
    26581 tgcggcgacc catcgcgatc ttgccgcaga ggtgaatgcc gggcgttttc gccaggatct
    26641 ctactatcgc ctgaacgtgg tggcgattga agtaccatcg ctgcgtcagc ggcgggaaga
    26701 tattcctctg ctggcaaacc attttcttca gcgctttgcc gagcgtaatc gcaaggcggt
    26761 aaaaggtttt acgccccagg cgatggatct gctgattcac tacgactggc cgggaaatat
    26821 tcgtgaactg gaaaacgcgg tggaacgggc ggtggtgctg ctgaccgggg aatatatttc
    26881 cgaacgcgag ctgccgctgg cgattgcgag tacgccgatc ccgctggtac aaagtcagga
    26941 tattcagccg ctggtggaag tcgaaaaaga ggtgattctt gcggcactgg agaaaacggg
    27001 cggcaacaaa accgaagccg cccgtcagtt agggatcacg cgcaaaacgc tcttggcaaa
    27061 actgtcgcgt tagttctgct cgcgttcgat agcgcgccag ccgatatctt tccggcagaa
    27121 gcagtcgtcc caatggatat cggtcattaa ggcataagcg cgtttctgcg cttctgccac
    27181 ggtatgaccc agcgcggtga cgcacagtac gcgcccgccg ctggtcacta cctgctcgtc
    27241 atccgccagt ttcgtgccag cgtggaacac tttgccgtca gacacttctt ccagcggcag
    27301 gccgtggatc acatcgccgg tgcggtaatc gcccggatat ccacccgcag ccatcaccac
    27361 gccgagagaa gcgcgttcat cccactcgga cgttttctcg tccagcttgc cttcacaggc
    27421 cgccaggcaa agctcaacca gatcggactt catgcgcagc ataatcggct gggtttctgg
    27481 atcgccaaag cggcagttaa attcaataac cttcggattg ccctgtttgt cgatcatcag
    27541 gcccgcgtag agaaaaccag tgtaggtgtt gccttctgcc gccatgcctt tcacggttgg
    27601 ccagatgatt cgttccatcg tgcgctgatg aacctcatcg gtcactactg gcgcagggga
    27661 gtaagcgccc atcccgccgg tgttcggccc ggtatcttta tcgcctacgc gtttgtgatc
    27721 ctggctggtg gccatcggca gcacatgctc gccgtctacc atcacgataa agctcgcttc
    27781 ttcgccgtcg aggaactctt cgataacaat gcgatgcccc gcgtcgccaa acgcgttgcc
    27841 cgccagcata tcgtgaacag ccgcttccgc ttcttccagc gtcatcgcta cgataacgcc
    27901 tttcccggca gccagaccgt cagctttaat gacgattggc gcgcctttct cacgcagata
    27961 cgccagcgca ggttctacct cggtgaagtt ctggtattcc gccgtaggga tcttatggcg
    28021 ggccaggaaa tctttggtaa acgcttttga gccttccagt tgggccgcac ctgcggttgg
    28081 gccgaagatt ttcagcccgg cggcgcggaa ggtatcaacc acgcctttca ccagcggcgc
    28141 ttccgggccg acgatggtta gatctacctt ttcgttttgt gcgaaatcca gcagcgccgg
    28201 gatatcggtt acgccgatat cgacgttttg cagtgcaggt tccagcgcag tgcctgcgtt
    28261 acccggagca acaaaaacag tttcaaccag cggcgactgc gccgctttcc aggccagcgc
    28321 gtgctcgcgc ccgccattac cgatcactaa tactttcatc tgtcgctcca ttaatggcgg
    28381 aagtggcgca tgtcggtgaa gagcatcgca ataccgtgct cgtcggcggc ggcaattact
    28441 tcgtcatcac ggatagaacc gccaggctgg attacacagg tcacacccgc agcggcggcg
    28501 gcatcaatac cgtcgcggaa cgggaagaat gcgtcagaag ccatcgagga acctttcact
    28561 tccaggcctt catcggccgc tttaataccg gcgattttcg cggagtacac acggctcatc
    28621 tggcctgcgc caataccgat ggtcatattg tttttggcat agacgatagc attggatttc
    28681 acgaacttcg ccactttcca gcagaacagc gcatcacgca gttcctgttc gctcggctga
    28741 cgtttggtga cgacgcgcag ttcttctgca ccgaccatcc ccaggtctcg atcctgaacc
    28801 agcagaccgc cgttcacgcg tttgaaatca agacccggaa cacgctcgcc ccactgaccg
    28861 caggtcagga cgcgtacgtt ctgtttggcg gcggtgattt tcagggcttc ttcgctggcg
    28921 gacggcgcaa taatcacttc aacaaactga cgagaaatga tggcctgcgc ggtttccgca
    28981 tccagctcgc ggttaaaggc gataatgccg ccgaatgcgg aggtcgggtc ggttttgtac
    29041 gcgcgatcgt aagcatcaag aatggaattg ccgatagcca cgccgcaagg gttggcgtgc
    29101 ttcacaatca cacatgccgg ctcggcgaac tctttcacgc actccagcgc cgcatcggta
    29161 tcggcgatgt tgttataaga gagggcttta ccctgaacct gggttgcggt agcaacggag
    29221 gcttctttga cattctcttc tatatagaag gcagcctgct ggtggctgtt ctcgccgtaa
    29281 cgcatatcct gcttcttaat gaagttcagg ttcagcgtgc gtgggaagcg accggcggct
    29341 tctttgcttt caccgtggta agccggaacc atgctgccga agtagttggc aatcatgctg
    29401 tcgtaggcgg cggtgtgttc gaaggctttg atggcaaggt caaagcgagt ttccagagtc
    29461 agggagcctt cattggcatc tatctcttta ataatggcgt cgtagtcgct gctcttcacc
    29521 acgatggcga catctttatg gttcttggcg gcagagcgca ccatcgttgg gccgccgata
    29581 tcgatgttct caaccgcatc ttccagcgag caaccttcac gggcaacggt ctgggcgaac
    29641 ggatacaggt taacaaccac catatcgata ggctggatct gatgttcttc cataatggca
    29701 tcgtcctggc cgcgacggcc cagaatgcca ccatgtactt tcggatgcag ggtcttcacg
    29761 cgtccatcca tcatctccgg gaaaccggtg taatcggaaa cttcggttac cggcagacct
    29821 ttttctgcta acagacgggc tgtgccccct gtagacagca gctccacacc gcgtgcggaa
    29881 agtgcctggg cgaattcgac gataccggct ttgtcagaaa cactgagcag agcgcggcgg
    29941 actggacgac gttgttgcat ggtaaatccc ctggatttga ctattacaga gagcgttagc
    30001 tgaatttttc gcgaaaaact cagctaacgc ccctaacggg gcatccttat ttttcgcccg
    30061 cattgtaacg aaaacgtttg cgcaacgctc gcgaattttt ctctttcaat ggtgatcaaa
    30121 attttgacag tggttaccgt gggaaaaata cagaaattac attgatgatt gtggataact
    30181 ctgtgcgtaa aaaggtataa agcggggttt tgctggggaa tgcagcagtc agtcattttt
    30241 ctgcaatttt tctattgcgg cctgcggaga actccctata atgcgcctcc attgacacgg
    30301 cggatgtgaa tcacttcaca caaacagccg gttcggttga agagaaaaat cctgaaattc
    30361 agggttgact ctgaaagagg aaagcgtaat atacgccacc tcgcgacagt gagctgaaag
    30421 c
//
LOCUS       DADXDL010000062        30385 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.062, whole genome shotgun sequence.
ACCESSION   DADXDL010000062 DADXDL010000000
VERSION     DADXDL010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 30385)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30385)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30385
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.062"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..418
                     /locus_tag="IRB70_003074"
     CDS             <1..418
                     /locus_tag="IRB70_003074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HBC0632958.1"
                     /translation="RALKALDRHLHEPGVAFTSTHAAREWLILNMAGLEREEFRVLYL
                     NNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAAVVLAHNHPSGEVTPSKADRL
                     ITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL"
     gene            481..702
                     /locus_tag="IRB70_003075"
     CDS             481..702
                     /locus_tag="IRB70_003075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HBC0632959.1"
                     /translation="MKIITRGEAMRIHQQHPTSRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            776..1144
                     /gene="cbtA"
                     /locus_tag="IRB70_003076"
     CDS             776..1144
                     /gene="cbtA"
                     /locus_tag="IRB70_003076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
                     /protein_id="HBC0632960.1"
                     /translation="MSDTLPGTTLPDDNHDRPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGLFSDADAYHLDQAFPLLMKQLELMLTSGELNPRHQHTVTLYAKGLTCKAD
                     TLSSCGYVYLAVYPTPEMKN"
     gene            1233..1607
                     /gene="cbtA"
                     /locus_tag="IRB70_003077"
     CDS             1233..1607
                     /gene="cbtA"
                     /locus_tag="IRB70_003077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system toxin CbtA"
                     /protein_id="HBC0632961.1"
                     /translation="MKTLPVLPGQAASSRPSPVEIWQILLSRLLDQHYGLTLNDTPFA
                     DERVIEQHIEAGISLCDAVNFLVEKYALVRTDQPGFSACTRSQLINSIDILRARRATG
                     LMTRDNYRTVNNITLGKYPEAK"
     gene            1604..1798
                     /locus_tag="IRB70_003078"
     CDS             1604..1798
                     /locus_tag="IRB70_003078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310834.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632962.1"
                     /translation="MMTLEADSVNVQALDMGHIVVDIDGVNITELINKAAENGYSLRV
                     VDDRDSTETPATYASPHQLL"
     gene            1811..1924
                     /locus_tag="IRB70_003079"
     CDS             1811..1924
                     /locus_tag="IRB70_003079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001161660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HBC0632963.1"
                     /translation="MQGIVPLTTETALLSCIKQAREDVLTLRHLQLLHQNR"
     gene            complement(2213..2341)
                     /locus_tag="IRB70_003080"
                     /pseudo
     CDS             complement(2213..2341)
                     /locus_tag="IRB70_003080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000080164.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            2413..2595
                     /locus_tag="IRB70_003081"
     CDS             2413..2595
                     /locus_tag="IRB70_003081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein"
                     /protein_id="HBC0632964.1"
                     /translation="MNHPVIGVVTKADLASMEQISLVKSWLREAGAHNVLVTSAVNNN
                     GVTELFALLHTEEGCC"
     gene            complement(2696..3025)
                     /locus_tag="IRB70_003082"
     CDS             complement(2696..3025)
                     /locus_tag="IRB70_003082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310836.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF496 family protein"
                     /protein_id="HBC0632965.1"
                     /translation="METTKPSFQDVLEFVRLFRRKNKLQREIQDVEKKIRDNQKRVLL
                     LDNLSDYIKPGMSVEAIQGIIASMKGDYEDRVDDYIIKNAELSKERRDISKKLKAMGE
                     MKNGEAK"
     gene            complement(3197..4255)
                     /locus_tag="IRB70_003083"
     CDS             complement(3197..4255)
                     /locus_tag="IRB70_003083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBC0632966.1"
                     /translation="MRADKSLSPFEIRVYRHYRIVHGTRVALAFLLTFLIIRLFTIPE
                     STWPLVTMVVIMGPISFWGNVVPRAFERIGGTVLGSILGLIALQLELISLPLMLVWCA
                     AAMFLCGWLALGKKPYQGLLIGVTLAIVVGSPTGEIDTALWRSGDVILGSLLAMLFTG
                     IWPQRAFIHWRIQLAKSLTEYNRVYQSAFSPNLLERPRLESHLQKLLTDAVKMRGLIA
                     PASKETRIPKSIYEGIQTINRNLVCMLELQINAYWATRPSHFVLLNAQKLRDTQHMMQ
                     QILLSLVHALYEGNPQPVFANTEKLNDAVEELRQLLNNHHDLKVVETPIYGYVWLNME
                     TAHQLELLSNLICRALRK"
     gene            complement(4453..4926)
                     /gene="sbmC"
                     /locus_tag="IRB70_003084"
     CDS             complement(4453..4926)
                     /gene="sbmC"
                     /locus_tag="IRB70_003084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase inhibitor SbmC"
                     /protein_id="HBC0632967.1"
                     /translation="MNYEIKQEEKRTVAGFHLVGPWEQTVKKGFEQLMMWVDSKNIVP
                     KEWVAVYYDNPDETPAEKLRCDTVVTVPGYFTLPENSEGVILTEITGGQYAVAVARVV
                     GDDFAKPWYQFFNSLLQDSAYEMLPKPCFEVYLNNGAEDGYWDIEMYVAVQPKHH"
     gene            complement(5045..6211)
                     /gene="dacD"
                     /locus_tag="IRB70_003085"
     CDS             complement(5045..6211)
                     /gene="dacD"
                     /locus_tag="IRB70_003085"
                     /EC_number="3.4.16.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416514.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine-type D-Ala-D-Ala carboxypeptidase DacD"
                     /protein_id="HBC0632968.1"
                     /translation="MKRRLIIAASLFVFNLSSGFAAENIPFSPQPPEIHAGSWVLMDY
                     TTGQILTAGNEHQQRNPASLTKLMTGYVVDRAIDSHRITPDDIVTVGRDAWAKDNPVF
                     VGSSLMFLKEGDRVSVRDLSRGLIVDSGNDACVALADYIAGGQRQFVEMMNNYAEKLH
                     LKDTHFETVHGLDAPGQHSSAYDLAVLSRAIIHGEPEFYHMYSEKSLTWNGITQQNRN
                     GLLWDKTMNVDGLKTGHTSGAGFNLIDSAVDGQRRLIAVVMGADSAKGREEEARKLLR
                     WGQQNFTTVQILHRGKKVGTERIWYGDKENIDLGTEQEFWMVLPKAEIPHIKAKYTLD
                     GKELTAPISAHQRVGEIELYDRDKQVAHWPLVTLESVGEGSMFSRLSDYFHHKA"
     gene            6420..7847
                     /gene="sbcB"
                     /locus_tag="IRB70_003086"
     CDS             6420..7847
                     /gene="sbcB"
                     /locus_tag="IRB70_003086"
                     /EC_number="3.1.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease I"
                     /protein_id="HBC0632969.1"
                     /translation="MMNDGKQQSTFLFHDYETFGTHPALDRPAQFAAIRTDSEFNVIG
                     EPEVFYCKPADDYLPQPGAVLITGITPQEARAKGENEAAFAARIHSLFTVPKTCILGY
                     NNVRFDDEVTRNIFYRNFYDPYAWSWQHDNSRWDLLDVMRACYALRPEGINWPENDDG
                     LPSFRLEYLTKANGIEHSNAHDAMADVYATIAMAKLVKTRQPRLFDYLFTHRNKHKLM
                     ALIDVPQMKPLVHVSGMFGAWRGNTSWVAPLAWHPENRNAIIMVDLAGDISPLLELDS
                     DTLRERLYTAKTDLGDNAAVPVKLVHINKCPVLAQANTLRPEDADRLGINRQHCLDNL
                     KILRENPQVREKVVAIFAEAEPFTPSDNVDAQLYNGFFSDADRAAMKIVLETEPRNLP
                     ALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRRQVFTPEFLQGYADELQML
                     AQQYADNKEKVALLKALWQYAEEIV"
     gene            complement(7890..8117)
                     /locus_tag="IRB70_003087"
     CDS             complement(7890..8117)
                     /locus_tag="IRB70_003087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase TusA family protein"
                     /protein_id="HBC0632970.1"
                     /translation="MAIKKLDVVTQVCPFPLIEAKAALAEMASGDELVIEFDCTQATE
                     AIPQWAAEEGHAITDYQQIGDAAWSITVQKA"
     gene            complement(8131..9189)
                     /gene="yeeE"
                     /locus_tag="IRB70_003088"
     CDS             complement(8131..9189)
                     /gene="yeeE"
                     /locus_tag="IRB70_003088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transport protein YeeE"
                     /protein_id="HBC0632971.1"
                     /translation="MFSMILSGLICGALLGFVMQRGRFCLTGGFRDMYIAKNNRMFYA
                     LLIAISVQSVGVFALIQAGLLTYEAGAFPWLGTVIGGYIFGLGIVLAGGCATGTWYRA
                     GEGLIGSWIALFTYMVMSAVMRSPHASVLNQTLQHYSTEHNSIAETFNLSVWPLVTVL
                     LVITLLVVMKELKKPKLKVATLPPRRTGIAHILFEKRWHPFVTAVLIGLIALLAWPLS
                     EATGRMFGLGITSPTANILQFLVAGDVKYINWGVFLVLGIFVGSFIAAKASREFRVRA
                     ADAQTTLRSGLGGVLMGFGASIAGGCSIGNGLVMTAMMTWQGWIGLVFMILGVWTASW
                     LVYVRPQRKARLATAAAN"
     gene            complement(9368..10726)
                     /gene="plaP"
                     /locus_tag="IRB70_003089"
     CDS             complement(9368..10726)
                     /gene="plaP"
                     /locus_tag="IRB70_003089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416518.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine/proton symporter PlaP"
                     /protein_id="HBC0632972.1"
                     /translation="MSHNVTPNTSRVELRKTLTLVPVVMMGLAYMQPMTLFDTFGIVS
                     GLTDGHVPTAYAFALIAILFTALSYGKLVRRYPSAGSAYTYAQKSISPTVGFMVGWSS
                     LLDYLFAPMINILLAKIYFEALVPSIPSWMFVVALVAFMTAFNLRSLKSVANFNTVIV
                     VLQVVLIAVILGMVVYGVFEGEGAGTLASTRPFWSGDAHVIPMITGATILCFSFTGFD
                     GISNLSEETKDAERVIPRAIFLTALIGGMIFIFATYFLQLYFPDISRFKDPDASQPEI
                     MLYVAGKAFQVGALIFSTITVLASGMAAHAGVARLMYVMGRDGVFPKSFFGYVHPKWR
                     TPAMNIILVGAIALLAINFDLVMATALINFGALVAFTFVNLSVISQFWIREKRNKTLK
                     DHFQYLFLPMCGALTVGALWVNLEESSMVLGLIWAAIGLIYLACVTKSFRNPVPQYED
                     VA"
     gene            complement(10716..10778)
                     /gene="yoeI"
                     /locus_tag="IRB70_003090"
     CDS             complement(10716..10778)
                     /gene="yoeI"
                     /locus_tag="IRB70_003090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YoeI"
                     /protein_id="HBC0632973.1"
                     /translation="MGQFFAYATVITVKENDHVA"
     gene            complement(10993..11922)
                     /locus_tag="IRB70_003091"
     CDS             complement(10993..11922)
                     /locus_tag="IRB70_003091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416519.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0632974.1"
                     /translation="MKPLLDVLMILDALEKEGSFAAASAKLYKTPSALSYTVHKLESD
                     LNIQLLDRSGHRAKFTRTGKMLLEKGREVLHTVRELEKQAIKLHEGWENELVIGVDDT
                     FPFSLLAPLIEAFYQHHSVTRLKFINGVLGGSWDALTQGRADIIVGAMHEPPSSSEFG
                     FSRLGDLEQVFAVAPHHPLALEEEPLNRRIIKRYRAIVVGDTAQAGASTASQLLDEQE
                     AITVFDFKTKLELQISGLGCGYLPRYLAQRFLDSGALIEKKVVAQTLFEPVWIGWNEQ
                     TAGLASGWWRDEILANSAIAGVYAKSDDGKSAI"
     gene            complement(11968..12792)
                     /locus_tag="IRB70_003092"
     CDS             complement(11968..12792)
                     /locus_tag="IRB70_003092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBC0632975.1"
                     /translation="MKKVAIVGLGWLGMPLAMSLSARGWQVTGSKTTQDGVEASRMSG
                     IDSYLLRMEPELVCDSDDLDALMDVDALVITLPARRSGPGDEFYLQAVQELVDSALAH
                     RIPRIIFTSSTSVYGDAQGTVKETTPRNPVTNSGRVLEELEDWLHNLPGTSVDILRLA
                     GLVGPGRHPGRFFAGKTAPDGEHGVNLVHLEDVIGAITLLLQAPKGGHIYNICAPAHP
                     ARNVFYPQMARLLGLEPPQFRNSLDSGKGKIIDGSRICNELGFEYQYPDPLVMPLE"
     gene            complement(12875..13129)
                     /gene="yoeB"
                     /locus_tag="IRB70_003093"
     CDS             complement(12875..13129)
                     /gene="yoeB"
                     /locus_tag="IRB70_003093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system mRNA interferase
                     toxin YoeB"
                     /protein_id="HBC0632976.1"
                     /translation="MKLIWSEESWDDYLYWQETDKRIVKKINELIKDTRRTPFEGKGK
                     PEPLKHNLSGFWSRRITEEHRLVYAVTDDSLLIAACRYHY"
     gene            complement(13126..13377)
                     /gene="yefM"
                     /locus_tag="IRB70_003094"
     CDS             complement(13126..13377)
                     /gene="yefM"
                     /locus_tag="IRB70_003094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoeB-YefM toxin-antitoxin system antitoxin YefM"
                     /protein_id="HBC0632977.1"
                     /translation="MRTISYSEARQNLSATMMKAVEDHAPILITRQNGEACVLMSLEE
                     YNSLEETAYLLRSPANARRLMDSIDSLKSGKGTEKDIIE"
     gene            13659..13709
                     /gene="hisL"
                     /locus_tag="IRB70_003095"
     CDS             13659..13709
                     /gene="hisL"
                     /locus_tag="IRB70_003095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="his operon leader peptide"
                     /protein_id="HBC0632978.1"
                     /translation="MTRVQFKHHHHHHHPD"
     misc_feature    13685..13808
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00514"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="His leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00514"
     gene            13855..14754
                     /gene="hisG"
                     /locus_tag="IRB70_003096"
     CDS             13855..14754
                     /gene="hisG"
                     /locus_tag="IRB70_003096"
                     /EC_number="2.4.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP phosphoribosyltransferase"
                     /protein_id="HBC0632979.1"
                     /translation="MTDNTRLRIAMQKSGRLSDDSRELLARCGIKINLHTQRLIAMAE
                     NMPIDILRVRDDDIPGLVMDGVVDLGIIGENVLEEELLNRRAQGEDPRYFTLRRLDFG
                     GCRLSLATPVDEAWDGPLSLNGKRIATSYPHLLKRYLDQKGISFKSCLLNGSVEVAPR
                     AGLADAICDLVSTGATLEANGLREVEVIYRSKACLIQRDGEMEESKQQLIDKLLTRIQ
                     GVIQARESKYIMMHAPTERLDEVIALLPGAERPTILPLAGDQQRVAMHMVSSETLFWE
                     TMEKLKALGASSILVLPIEKMME"
     gene            14760..16064
                     /gene="hisD"
                     /locus_tag="IRB70_003097"
     CDS             14760..16064
                     /gene="hisD"
                     /locus_tag="IRB70_003097"
                     /EC_number="1.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol dehydrogenase"
                     /protein_id="HBC0632980.1"
                     /translation="MSFNTIIDWNSCTAKQQRQLLMRPAISASESITRTVNDILDSVK
                     ARGDDALREYSAKFDKTTVTALKVSAEEIAAASERLSDELKQAMAVAVKNIETFHTAQ
                     KLPPVDVETQPGVLCQQVTRPVASVGLYIPGGSAPLFSTVLMLATPARIAGCNKVVLC
                     SPPPIADEILYAAQLCGVQDVFNVGGAQAIAALAFGTESVPKVDKIFGPGNAFVTEAK
                     RQVSQRLDGAAIDMPAGPSEVLVIADSGATPDFVASDLLSQAEHGPDSQVILLTPDAD
                     MARRVAEAVERQLAELPRAETARQALNASRLIVTKDLAQCVEISNQYGPEHLIIQTRN
                     ARDLVDGITSAGSVFLGDWSPESAGDYASGTNHVLPTYGYTATCSSLGLADFQKRMTV
                     QELSKVGFSALASTIETLAAAERLTAHKNAVTLRVNALKEQA"
     gene            16061..17131
                     /gene="hisC"
                     /locus_tag="IRB70_003098"
     CDS             16061..17131
                     /gene="hisC"
                     /locus_tag="IRB70_003098"
                     /EC_number="2.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol-phosphate transaminase"
                     /protein_id="HBC0632981.1"
                     /translation="MSTVTITDLARENVRNLTPYQSARRLGGNGDVWLNANEYPTAVE
                     FQLTQQTLNRYPECQPKAVIENYAQYAGVKPEQVLVSRGADEGIELLIRAFCEPGKDA
                     ILYCPPTYGMYSVSAETIGVECRTVPTLENWQLDLQGISDKLDGVKVVYVCSPNNPTG
                     QLINPQDFRTLLELTRGKAIVVADEAYIEFCPQASLAGWLAEYPHLAILRTLSKAFAL
                     AGLRCGFTLANEEVINLLMKVIAPYPLSTPVADIAAQALSPQGIVAMRERVAQIIAER
                     EYLIAALKEISCVEQVFDSETNYILARFKASSAVFKSLWDQGIILRDQNKQPSLSGCL
                     RITVGTREESQRVIDALRAEQV"
     gene            17131..18198
                     /gene="hisB"
                     /locus_tag="IRB70_003099"
     CDS             17131..18198
                     /gene="hisB"
                     /locus_tag="IRB70_003099"
                     /EC_number="3.1.3.15"
                     /EC_number="4.2.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416526.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     histidinol-phosphatase/imidazoleglycerol-phosphate
                     dehydratase HisB"
                     /protein_id="HBC0632982.1"
                     /translation="MSQKYLFIDRDGTLISEPPSDFQVDRFDKLAFEPGVIPELLKLQ
                     KAGYKLVMITNQDGLGTQSFPQADFDGPHNLMMQIFTSQGVQFDEVLICPHLPADECD
                     CRKPKVKLVERYLAEQAMDRANSYVIGDRATDIQLAENMGITGLRYDRETLNWPMIGE
                     QLTKRDRYAHVVRNTKETQIDVQVWLDREGGSKINTGVGFFDHMLDQIATHGGFRMEI
                     NVKGDLYIDDHHTVEDTGLALGEALKIALGDKRGLCRFGFVLPMDECLARCALDISGR
                     PHLEYKAEFTYQRVGDLSTEMIEHFFRSLSYTMGVTLHLKTKGKNDHHRVESLFKAFG
                     RTLRQAIRVEGDTLPSSKGVL"
     gene            18198..18788
                     /gene="hisH"
                     /locus_tag="IRB70_003100"
     CDS             18198..18788
                     /gene="hisH"
                     /locus_tag="IRB70_003100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005128083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisH"
                     /protein_id="HBC0632983.1"
                     /translation="MNVVILDTGCANLNSVKSAIARHGYEPKVSRDPDVVLLADKLFL
                     PGVGTAQAAMDQVRERELFDLIKACTQPVLGICLGMQLLGRRSEESNGVDLLGIIDED
                     VPKMTDFGLPLPHMGWNRVYPQAGNRLFQGIEDGAYFYFVHSYAMPVNPWTIAQCNYG
                     EPFTAAVQKDNFYGVQFHPERSGAAGAKLLKNFLEM"
     gene            18788..19525
                     /gene="hisA"
                     /locus_tag="IRB70_003101"
     CDS             18788..19525
                     /gene="hisA"
                     /locus_tag="IRB70_003101"
                     /EC_number="5.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416528.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-(5-phosphoribosyl)-5-[(5-
                     phosphoribosylamino)methylideneamino]imidazole-4-
                     carboxamide isomerase"
                     /protein_id="HBC0632984.1"
                     /translation="MIIPALDLIDGTVVRLHQGDYGKQRDYGNDPLPRLQDYAAQGAE
                     VLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRSEEDVAALLEAGVARVVVG
                     STAVKSQDMVKGWFERFGADALVLALDVRIDEQGNKQVAVSGWQENSGVSLEQLVETY
                     LPVGLKHVLCTDISRDGTLAGSNVSLYEEVCARYPQVAFQSSGGIGDIDDVAALRGTG
                     VRGVIVGRALLEGKFTVKEAIACWQNA"
     gene            19507..20283
                     /gene="hisF"
                     /locus_tag="IRB70_003102"
     CDS             19507..20283
                     /gene="hisF"
                     /locus_tag="IRB70_003102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazole glycerol phosphate synthase subunit
                     HisF"
                     /protein_id="HBC0632985.1"
                     /translation="MLAKRIIPCLDVRDGQVVKGVQFRNHEIIGDIVPLAKRYAEEGA
                     DELVFYDITASSDGRVVDKSWVSRVAEVIDIPFCVAGGIKSLDDAAKILSFGADKISI
                     NSPALADPTLITRLADRFGVQCIVVGIDTWYDGETGKYHVNQYTGDESRTRVTQWETL
                     DWVQEVQKRGAGEIVLNMMNQDGVRNGYDLEQLKKVREVCHVPLIASGGAGTMEHFLE
                     AFRDADVDGALAASVFHKQIINIGELKAYLATQGVEIRIC"
     gene            20277..20885
                     /locus_tag="IRB70_003103"
     CDS             20277..20885
                     /locus_tag="IRB70_003103"
                     /EC_number="3.5.4.19"
                     /EC_number="3.6.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional phosphoribosyl-AMP
                     cyclohydrolase/phosphoribosyl-ATP diphosphatase HisIE"
                     /protein_id="HBC0632986.1"
                     /translation="MLTEQQRRELDWEKTDGLMPVIVQHAVSGEVLMLGYMNPEALDK
                     TIESGKVTFFSRTKQRLWTKGETSGNFLNVVNIAPDCDNDTLLVLANPIGPTCHKGTS
                     SCFGETAHQWLFLYQLEQLLAERKSADPETSYTAKLYASGTKRIAQKVGEEGVETALA
                     ATVHDRFELTNEASDLMYHLLVLLQDQGLDLGEVIDNLKNRH"
     gene            complement(20924..22039)
                     /locus_tag="IRB70_003104"
     CDS             complement(20924..22039)
                     /locus_tag="IRB70_003104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004184789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBC0632987.1"
                     /translation="MRVLHVYKTYYPDTYGGIEQVIYQLSQGCARRGIAADVFTFSPD
                     KDTGPVAYEDHRVIYNKQLFEIASTPFSLKALKRFKLIKDDYDIINYHFPFPFMDMLH
                     LSARPDARTVVTYHSDIVKQKRLMKLYQPLQERFLSGVDCIVASSPNYVASSQTLKKY
                     LDKTVVIPFGLEQQDVQHDPQRVAHWRETVGDKFFLFVGTFRYYKGLHILMDAAERSR
                     LPVVVVGGGPLESEVRREAQQRGLSNVMFTGMLNDEDKYILFQLCRGVVFPSHLRSEA
                     FGITLLEGARFARPLISCEIGTGTSFINQDKVSGCVIPPNDSQALVEAMNELWNNEET
                     SNRYGENSRRRFEEMFTADHMIDAYVNLYTTLLESKS"
     gene            complement(22049..23194)
                     /locus_tag="IRB70_003105"
     CDS             complement(22049..23194)
                     /locus_tag="IRB70_003105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016809192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBC0632988.1"
                     /translation="MKIIFATEPIKYPLTGIGRYSLELVKRLAVAREIEELKLFHGAS
                     FIEQIPLVENKSDTKASNHGRLSAFLRRQTLLIEAYRLLHPRRQAWALRDYKDYIYHG
                     PNFYLPHKLERAVTTFHDISIFTCPEYHPKDRVRYMEKSLHESLDSAKLILTVSDFSR
                     SEIIRLFNYPEERIVTTKLACSSDYIPRSPAECLPVLQKYQLAWQAYALYIGTMEPRK
                     NIRGLLHAYQLLPMEIRMRYPLILSGYRGWEDDVLWQLVELGTREGWIRYLGYVPDED
                     LPYLYAAARVFVYPSFYEGFGLPILEAMSCGVPVVCSNVTSLPEVVGDAGLVADPNDI
                     DAISAQILQSLQDDSWREIATARGLAQAKQFSWENCATQTINAYKLL"
     gene            complement(23258..26899)
                     /locus_tag="IRB70_003106"
     CDS             complement(23258..26899)
                     /locus_tag="IRB70_003106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001223552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBC0632989.1"
                     /translation="MRIVIDLQGAQTESRFRGIGRYSIAIARGIIRNNSRHEIFIALS
                     AMLDESIADIKAQFADLLPAENIVVWHAVGPVRAMDQGNEWRRESAELIREAFLESLC
                     PDVVFITSLFEGHVDDAATSVHKFSRQYKVAVLHHDLIPLVQAETYLQDDVYKPYYLQ
                     KVEWLKNADLLLTNSAYTAQEAIEHLHLQGDHVQNIAAAVDSQFCMAEVAASEKETVL
                     GHYGIQREFMLYAPGGFDSRKNFKRLIEAYAGLSDALRRSHQLVIVSKLSIGDRQYLE
                     SLASGNGLQQGELVLTGYVPEDELIQLYRLCKLFIFASLHEGFGLPVLEAMSCGAPVI
                     GSNVTSIPEVIDNPEALFDPYSVSSMRDKIAQCLTDDTFLARLKEIAQQQARNFSWDK
                     AAVTALEAFEKIAVEDTGTAQVLPEALIQKILAIPQGQPDDRDLRLCATAIDYNLKTA
                     ELYQIDDKSLNWRVEGPFDSSYSLSLVNREFVRALSADGVEVLLHSTEGPGDFAPDAS
                     FMAQSENSDLLAFYNQCQTRKSNEKIDILSRNIYPPRVTKMDAKVKFLHCYAWEETGF
                     PQPWINEFNRELDGVLCTSEHVRKILIDNGLNVPAFVVGNGCDHWLNIPAETTKDVDH
                     GTFRFLHVSSCFPRKGIQAMLQAWGKAFTRRDNVILIIKTFNNPHNEIDAWLAQAQAQ
                     FIDYPKVEVIKEDISATELKGLYESCDVLVAPGCAEGFGLPIAEAMLSGLPAIVTNWS
                     GQLDFVNSQNSWLVDYQFTRVKTHFGLFSSAWASVDIDNLTDALKAAASTDKSVLRDM
                     ANAGRELLLQQFTWKAVADRSCQAVKTLRAHIDIAQHRARIGWLTTWNTKCGIATYSQ
                     HLVESAPHGADVVFAPQVSAGDLVCADEEFVLRNWIVGKESNYLENLQPHIDALKLDV
                     IVIQFNYGFFNHRELSVFIRRQHDAGRSVVMTMHSTVDPLEKEPSWNFRLAEMKEALA
                     LCDRLLVHSIADMNRLKDLGLTANVALFPHGVINYSAASVTRQQQSLPLIASYGFCLP
                     HKGLMELVESVHRLKQAGKPVRLRLVNAEYPVGESRDLVAELKAAAQRLGVTDLIEMH
                     NDFLPDAESLRLLSEADLLIFAYQNTGESASGAVRYGMATQKPVAVTPLAIFDDLDDA
                     VFKFDGCSVDDISQGIDRILNSIREQNSWATRTQQRADAWREQHDYQAVSRRLVNMCQ
                     GLAKAKYFK"
     gene            complement(26902..28179)
                     /locus_tag="IRB70_003107"
     CDS             complement(26902..28179)
                     /locus_tag="IRB70_003107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015365812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBC0632990.1"
                     /translation="MGSSFYRSFEERHRGSVEEIKRRLSFYLPFLAGLKDIYPDGMIA
                     DIGCGRGEWLEILTENGIANIGVDLDDGMLARAREAGLNVQKMDCLQFLQSQADQSLI
                     ALTGFHIAEHLPFEVLQQLVMHTLRVLKPGGLLILETPNPENVSVGTCSFYMDPTHNH
                     PLPPPLLEFLPIHYGFNRAITVRLQEKEVLQSPDAAVNLVDVLKGVSPDYSIIAQKAA
                     PTDILERFDTLFTQQYGLTLDALSNRYDAILRQQFSSVVSRLETLNQTYMQQISQMSE
                     TIQTLQGEVDDLSHVIDQNHQLHQQMADLHNSRSWRITQPLRWLSLQRHLLRQEGAKV
                     RARRAAKKILRKGMALSLVFFHRYPKSKVYLFKVLRKTGCYTLLQRLFQRVMLVQSDT
                     IMMQSRRYDVGTEEMTSRAMSIYNELKNKNTEK"
     gene            complement(28179..29393)
                     /locus_tag="IRB70_003108"
     CDS             complement(28179..29393)
                     /locus_tag="IRB70_003108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000120467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O8 family O-antigen ABC transporter ATP-binding
                     protein Wzt"
                     /protein_id="HBC0632991.1"
                     /translation="MSYIRVNNVGKAYRQYHSKTGRLIEWLSPLNTKRHNLKWILREI
                     NFEVAPGEAVGIIGINGAGKSTLLKLITGTSRPTTGEIEISGRVAALLELGMGFHSDF
                     TGRQNVYMSGQLLGLSSEKITELMPQIEEFAEIGDYIDQPVRVYSSGMQVRLAFSVAT
                     AIRPDVLIIDEALSVGDAYFQHKSFERIRKFRQEGTTLLLVSHDKQAIQSICDRAILL
                     NKGQIEMEGEPEAVMDYYNALLADKQNQSIKQVEHNGKTQTVSGTGEVTISEVHLLDE
                     QGNVTEFVSVGHRVSLQVNVEVKDDIPELVVGYMIKDRLGQPIFGTNTYHLNQTLTSL
                     KKGEKRSFLFSFDARLGVGSYSVAVALHTSSTHLGKNYEWRDLAVVFNVVNTEQQEFV
                     GVSWLPPELEIS"
     gene            complement(29393..30187)
                     /locus_tag="IRB70_003109"
     CDS             complement(29393..30187)
                     /locus_tag="IRB70_003109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001308747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O8 family O-antigen ABC transporter permease
                     subunit Wzm"
                     /protein_id="HBC0632992.1"
                     /translation="MRDLLTTIYRYRGFIWSSVKRDFQARYQTSMLGALWLVLQPLSM
                     ILVYTLVFSEVMKARMPDNTGSFAYSIYLCSGVLTWGLFTEMLDKGQSVFINNANLIK
                     KLSFPKICLPIIVTLSAVLNFAIIFSLFLIFIIVTGNFPGWLFLSVIPVLLLQILFAG
                     GLGMILGVMNVFFRDVGQLVGVALQFWFWFTPIVYVLNSLPAWAKNLMMYNPMTRIMQ
                     SYQSIFAYHLAPNWYSLWPVLALAIIFCVIGFRMFRKHAADMVDEL"
     gene            complement(30189..>30385)
                     /locus_tag="IRB70_003110"
     CDS             complement(30189..>30385)
                     /locus_tag="IRB70_003110"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003596869.1"
                     /note="capsular polysaccharide biosynthesis protein;
                     catalyzes the formation of D-mannose 6-phosphate from
                     alpha-D-mannose 1-phosphate; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphomannomutase CpsG"
                     /protein_id="HBC0632993.1"
                     /translation="RAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESR
                     ADTALMNAKTTELLHLLSGE"
BASE COUNT         7914 a         7944 c         7348 g         7179 t
ORIGIN      
        1 gcgggccctg aaagccctgg accgccatct tcatgaaccc ggcgtggcct tcacctccac
       61 gcatgcggca cgggaatggc tgattctgaa catggcggga ctggagcggg aagagttccg
      121 ggtgctgtat ctgaacaacc agaatcagct gattgccggt gaaaccctct tcaccggcac
      181 catcaaccgt acggaagttc atccccggga agtgattaaa cgcgccctgt accacaatgc
      241 cgctgccgtg gtgctggcgc acaatcaccc gtccggtgaa gtcaccccca gcaaggcaga
      301 ccggcttatc accgaacgtc tggtacaggc actgggcctg gtggatatcc gggtgccgga
      361 ccatctgata gtcggtggca accaggtttt ctcctttgcc gaacatggtc tgctttaacc
      421 cttcacaacc acatcacacc tgttttcact tttatcttct gtcttcagag gtatcccatt
      481 atgaaaatta tcacccgtgg tgaagccatg cgtattcacc aacaacatcc gacatcccgt
      541 ctttttccgt tctgtaccgg taaataccgc tggcacggca gtgctgaagc gtataccggt
      601 cgtgaagtgc aggatattcc cggtgtgctg gccgtgtttg ctgaacgccg taaggacagt
      661 tttggtccgt atgtccggct gatgagcgtc accctgaact gagtgggaat tctgatgagc
      721 agaattatcg ccactaccgg accattctta gccgattttc tgtaaggatt ttatcgtgtc
      781 agacacactc cccgggacaa cacttcccga cgacaatcac gaccgcccct ggtgggggct
      841 gccctgcacc gtgacgccct gtttcggggc acgtctggtg caggagggta accggttgca
      901 ttaccttgcc gaccgcgccg gtatcagagg cctgttcagc gatgcagatg cgtaccacct
      961 ggaccaggcc tttccgctgc tgatgaaaca actggaactc atgctcacca gcggtgaact
     1021 gaatccccgc catcagcata ccgtcacgct gtatgcaaaa gggctgacct gcaaagccga
     1081 taccctcagc agttgtggtt acgtttatct ggctgtttat ccgacgcccg aaatgaaaaa
     1141 ttaactctcc agaatagcct tctgctacgg cctggtgttt tcaccacgcc acttttccat
     1201 ttttatatct gcatatcagg aaaatcttca gtatgaaaac attacctgta ttacccgggc
     1261 aggcggccag ttctcgcccg tctcctgttg aaatctggca gatactgctg tcccgactgc
     1321 tggaccagca ttatggcctc acactgaatg acacaccttt tgccgatgaa cgtgtgattg
     1381 agcagcatat tgaggcaggc atttcactgt gtgatgcggt gaactttctc gtggaaaaat
     1441 acgcgctggt gcgtaccgac cagccgggat tcagcgcctg tacccgctct cagttaataa
     1501 acagtattga tatcctccgg gcacgccggg caaccggcct gatgacccgc gacaattaca
     1561 gaacggtaaa taacattacc ctgggtaagt atccggaggc gaaatgatga cactggaagc
     1621 cgacagcgtt aacgtacagg cgctggatat ggggcacatt gtcgttgaca ttgatggtgt
     1681 taatatcact gaactgatta ataaggccgc tgaaaacggt tattcactcc gcgtggtgga
     1741 tgaccgtgac tctaccgaaa caccggcaac ttatgccagc cctcaccagt tgctgtaaga
     1801 caatgcagtg atacagggta tagtgccatt aaccacagaa acagcactgt tgtcctgtat
     1861 taagcaggca agagaagatg tccttaccct gcgccatctg cagcttctgc accagaaccg
     1921 gtgaatctca ctcaacaggc ttcatttctc ctgacgccag cctgaataca gctggcgttt
     1981 tcatttataa acagaaagga aaaccgataa taatggaatg gacgccccga ccatgaagca
     2041 acggtaggat attactgata aaccttccag tggaggtgcg ttatggccgt tttaacgatt
     2101 agcattgacc tgacaaaaaa tgaattccaa atccacggtc tgggtaggaa cagaaaaatc
     2161 taagctcaga aaacggatta aagtaagcgt caacggagca ccgtattgac gcttatttat
     2221 tggtgagaac tacgttccat ggcaggagtt cgtcaacacg gttggagggc cattccggca
     2281 gtatgctcag aatatggcgc agatacgctt ccggatcgat accgttcaga cggcaggtgc
     2341 ctgcttttct ggcaacaagc aggaatctca gcgctgaagc aggaattaga ggtaaaaacg
     2401 ccctaccggg ccatgaatca cccggtcatt ggagtagtaa ccaaagcaga tttagccagc
     2461 atggaacaaa tatctttggt gaaaagttgg ttacgggaag ctggagcgca caacgtgtta
     2521 gtaaccagtg cagttaataa caatggagtt acagaacttt ttgccttgct gcatacagaa
     2581 gaaggctgtt gttaatttcg attggttctc ggatgagaat gatgacggtg atacacagat
     2641 aagaatcaat gagcaatgag ggttgccggg caaccctcat tgaataaaac gggaattact
     2701 tcgcttcgcc gtttttcatt tcgcccatag ctttcagctt tttggagata tcgcggcgtt
     2761 ctttggagag ctcggcattt ttgatgatgt aatcgtcaac gcgatcttca tagtcacctt
     2821 tcatgctggc gatgatgccc tggattgctt caacgctcat ccccggcttg atgtaatcgc
     2881 tcaggttgtc cagcagcagg acgcgcttct ggttgtcacg gatctttttc tcaacgtcct
     2941 gaatttcacg ttgcagtttg ttcttacgac ggaacagacg aacaaattcc agtacgtcct
     3001 ggaatgaagg cttggtagtt tccattttta tacccctgat aatgtgagag tcggattcgt
     3061 ttaagcaacc gctattcgtt agggccaaca ttactcatag ctgccgcaga tgacaatgct
     3121 tttatccctt ttcactatca taccctttat ccttgctgaa tcgaagcagc agcaagatga
     3181 ttctgaagtt caggaattat ttgcgcaagg cccggcaaat cagattcgat agcaactcaa
     3241 gctgatgcgc cgtttccatg ttcagccaca cataaccata gattggtgtt tccacaacct
     3301 tcaggtcatg gtggttattg agcaactgac gcagctcttc cacagcatcg ttcaattttt
     3361 ccgtattggc aaaaaccggc tgcggattac cttcgtacag cgcatgaaca aggctcagca
     3421 gtatttgctg catcatgtgc tgggtatcac gaagtttttg cgcgttcaat aacacgaaat
     3481 ggctggggcg cgtggcccag tatgcattga tttgcaactc cagcatacaa accagattgc
     3541 ggttaatggt ctggatacct tcatatatcg attttggaat acgggtttct ttgctggcgg
     3601 gcgcaatcag tccacgcatt ttcacggcat cggtcaggag tttttgtaga tggctttcca
     3661 gacgtgggcg ttcgagtaag ttcggtgaga atgcagattg atagacccga ttatactcgg
     3721 tcagactttt cgccagttga atgcgccagt ggatgaacgc ccgttgtggc cagataccgg
     3781 taaacaacat tgccagtaaa gagccgagga tcacatcgcc gcttcgccat aacgccgtat
     3841 caatttcacc tgtcggggaa cccacaacaa ttgccagcgt caccccaatc aataaacctt
     3901 gatacggttt cttgcccagc gccagccaac cgcaaaggaa catggccgcc gcgcaccaga
     3961 ctaacatcag cggtaacgag attaactcca gttgcagagc gataagacct aaaatcgaac
     4021 ccaacaccgt accgccaata cgctcaaagg cgcgagggac aacgttaccc cagaacgaga
     4081 ttggccccat aatcaccacc atggtgacca gcggccaggt gctttccggg atagtaaaca
     4141 ggcggataat gagaaaagtg agcaggaatg ccagcgcgac ccgagtacca tgcacaatgc
     4201 ggtaatggcg gtatacccgg atttcaaacg ggcttaatga cttatcggca cgcacgcaga
     4261 aactccgtaa tgagattaaa agcgctcata actcatctgt cggccagaag gcgcgcctct
     4321 gaattatccg acggacaaac cgggaacagt gtaatttccc ggcaggagcg aaaaaattga
     4381 aaggcgcatc ttactctttt cgctttcaaa aaaaagagtg gtcatcgcgt taacacaccg
     4441 ccctgagatg aattagtgat gttttggctg caccgcaaca tacatttcga tatcccagta
     4501 cccatcttcc gcgccattgt tcaaataaac ctcgaagcag ggctttggta acatttcata
     4561 agcactgtcc tgcaagagac tattaaagaa ctgataccag ggtttagcaa aatcatcacc
     4621 gactacacga gctaccgcca ccgcatactg accacctgta atttctgtca gaatgacgcc
     4681 ctcactgttt tcgggaagcg taaagtaacc cggcaccgtc acgacggtgt cgcagcgtaa
     4741 tttttcggcg ggtgtttcat ctggattgtc gtaatagaca gcaacccact ccttcggcac
     4801 aatatttttg ctatctaccc acatcatcaa ctgctcaaag cctttcttta ccgtctgttc
     4861 ccacgggcca acgagatgga aacctgcaac ggtacgtttc tcttcctgct taatctcgta
     4921 gttcatgacg cctccattga tactgttttt atatacagta tagttgcaaa attaaaacca
     4981 caaggaatga gtgttgatta tgcgagcaga ctcgcactcc tgccagtctg ctgcaaaaga
     5041 aaggtcaggc cttatggtgg aaataatcac tcaggcgaga aaacatgctg ccttccccga
     5101 cagattccag ggtaaccagc ggccagtgcg ccacctgttt atcacggtcg taaagttcaa
     5161 tttcccctac ccgctgatgg gcgctaattg gcgcggtgag ttctttacca tcaagggtat
     5221 atttggcttt gatatgtgga atttcggctt tcggtagcac catccagaac tcttgttccg
     5281 ttcccaggtc gatattttct ttatcgccat accagatgcg ttccgttccg acctttttcc
     5341 cacggtgcaa aatttgcacc gtagtaaagt tttgttgccc ccaacgcagt aattttcttg
     5401 cctcttcctc acgacctttt gcactgtcag cccccattac cactgcaatg agacgacgct
     5461 gcccatctac agccgaatca atgagattaa acccggcacc agaagtatga cccgttttca
     5521 ggccgtcaac attcatggtt ttatcccaca acaacccgtt acggttttgc tgggtgatac
     5581 cgttccaggt gagacttttc tcactgtaca tatgataaaa ctcgggctcg ccgtggatga
     5641 tagcacgaga aagcacagct aaatcataag ccgagctatg ctggccaggt gcatccagac
     5701 catgcactgt ttcaaaatgc gtatccttga gatgcagctt ctcggcatag ttgttcatca
     5761 tttcaacaaa ctgccgttgc ccaccggcaa tatagtcagc cagagcaaca caagcgtcat
     5821 ttccggaatc cacaattaaa ccacggctta aatcacgtac cgatacgcga tcgccctctt
     5881 tcaaaaacat cagtgaagaa ccgacaaaca ccggattatc tttcgcccac gcatcgcgcc
     5941 ccacggtgac aatatcgtct ggcgtaatgc gatgactatc gatagcgcga tccacgacat
     6001 aacccgtcat cagctttgtc aggctggcgg gattgcgctg ttgatgctca ttacccgcgg
     6061 tgaggatctg accggtggtg taatccatca atacccagga cccggcatga atctctggag
     6121 gctgaggtga aaaaggaatg ttttccgccg caaaaccaga cgataagtta aaaacgaaca
     6181 aagaagcagc aataataaga cggcgtttca acagcaaacc ctcaggagtt tcaaatagct
     6241 gttcttttta cggaaatact tatgaactgg ctggaataaa gtgcaagaaa atgtgactac
     6301 cctctcattt ttatctgaca tgatctgttg ccactcgctg ccaaattgtg gcgctaaagc
     6361 tgattagcac ggtgatattt gatactctgg cagacagcag aaataacgga tttaacctaa
     6421 tgatgaatga cggtaagcaa caatctacct ttttgtttca cgattacgaa acctttggca
     6481 cgcaccccgc gttagatcgc cctgcacagt tcgcagccat tcgcaccgat agcgaattca
     6541 atgtcatcgg cgaacccgaa gtcttttact gcaagcccgc tgatgactat ttaccccagc
     6601 caggagccgt attaattacc ggtattaccc cgcaggaagc acgggcgaaa ggagaaaacg
     6661 aagccgcgtt tgccgcccgt attcactcgc tttttaccgt accgaagacc tgtattctgg
     6721 gctacaacaa tgtgcgtttc gacgacgaag tcacacgcaa cattttttat cgtaatttct
     6781 acgatcctta cgcctggagc tggcagcatg ataactcgcg ctgggattta ctggatgtta
     6841 tgcgtgcctg ttatgccctg cgcccggaag gaataaactg gcctgaaaat gatgacggtc
     6901 taccgagctt tcgccttgag tatttaacca aagcgaatgg tattgaacat agcaacgccc
     6961 acgatgctat ggctgatgtg tacgccacta ttgcgatggc aaagctggta aaaacgcgtc
     7021 agccacgcct gtttgattat ctctttaccc atcgcaataa acacaaactg atggcgttga
     7081 ttgatgttcc gcagatgaaa cccctggtgc acgtttccgg aatgtttggg gcatggcgcg
     7141 gcaacaccag ctgggtggca ccgctggcgt ggcatcctga aaatcgcaat gccataatta
     7201 tggtggattt ggcaggagac atttcgccat tactggaact ggatagcgac acattgcgcg
     7261 agcgtttata taccgcaaaa accgatcttg gcgataacgc cgccgttccg gttaagctgg
     7321 tgcacatcaa taaatgtccg gtgctggccc aggcgaatac gctacgcccg gaagatgccg
     7381 accgactggg aattaatcgt cagcattgcc tcgataacct gaaaattctg cgtgaaaatc
     7441 cgcaagtgcg tgaaaaagtg gtggcgatat tcgcggaagc cgaaccgttt acgccttcag
     7501 ataacgtgga tgcacagctt tataacggct ttttcagtga cgccgatcgc gcagcaatga
     7561 aaattgtgct ggaaaccgag ccgcgtaatt taccggcact ggatatcact tttgttgata
     7621 aacgaattga aaaactgttg ttcaattatc gggcacgcaa cttcccgggg acgctggatt
     7681 atgccgagca gcaacgctgg ctggagcacc gccgccaggt cttcacgccc gagtttttac
     7741 aaggttatgc agatgaattg cagatgctgg cacaacaata tgccgataac aaagagaaag
     7801 tggcgctgtt aaaagcgctt tggcagtacg cggaagagat cgtctaattt gaagcctccg
     7861 ccgctggtac ggcggaggtc aatgttgagt caggcttttt gaacggtgat actccacgct
     7921 gcatcgccaa tctgctgata atcggtgatg gcatgccctt cttctgccgc ccactgtggg
     7981 attgcttcag ttgcctgggt gcaatcaaac tcaattacca actcatcgcc gctggccatt
     8041 tctgccagtg ctgcttttgc ttctatgagt ggaaacggac agacctgcgt caccacatcc
     8101 agctttttaa tcgccatctt tacaccttac ttaatttgcc gcagcagttg ccagtcgcgc
     8161 cttacgctgc ggtcgaacat acacaagcca ggacgcagtc cagactccga gaatcataaa
     8221 tacaaggcca atccagccct gccaggtcat cattgcagtc ataaccagtc cattaccgat
     8281 agagcaacca cctgcaatac tggcaccgaa gcccatcagt acaccaccta acccgctacg
     8341 taatgttgtt tgtgcatcag ctgcgcgaac gcggaactca cggctcgctt tggctgcaat
     8401 aaatgacccc acgaagatcc ctaacaccag gaaaacgccc cagttaatgt atttcacgtc
     8461 acccgcgacc agaaattgca gaatattggc cgttggggaa gtgattccta acccaaacat
     8521 gcgtccggtt gcttcactca ggggccaggc taaaagcgca atcaaaccga tgagtacagc
     8581 agtgacaaag ggatgccagc gtttttcaaa cagaatatga gcgatcccgg ttcggcgcgg
     8641 cggtaaggtc gcgactttga gttttggctt cttcaactct ttcatcacca ccaagagcgt
     8701 tatcaccagc aaaacggtaa ccaacggcca cacagacaaa ttaaaagtct cagcaataga
     8761 gttatgttca gtactgtagt gctgcaaggt ttgatttaaa acactggcat gtggagaacg
     8821 catcaccgca ctcatcacca tataagtgaa aagcgcgatc caactgccga tcaatccctc
     8881 acccgcgcga taccaggtcc cggtggcaca tccacccgcc agaacaattc ccagcccgaa
     8941 gatataccca cctataacag taccaagcca cgggaacgcc ccggcttcgt aagtcagtag
     9001 gcccgcctga attaacgcaa aaacccccac gctttgtacc gaaattgcaa tcagcaaggc
     9061 gtaaaacatg cgattatttt tcgcgatata catatcgcga aaaccacctg tcaggcaaaa
     9121 acgcccacgc tgcatgacaa atcccagcag agcaccacaa attagcccgc ttaatatcat
     9181 tgaaaacata aattaattaa ccagatgaat gttaatgagg aaattattca tgactggtgg
     9241 aatgcagacc aataaccaaa ttctctaaat tagaacaaat ggttattaat gaggatgtcg
     9301 ataaaaaaga ataaaaaaac cggagccaaa tattcattcg actccggttt attattagaa
     9361 aagatgatta tgctacgtct tcgtactgcg gaaccgggtt acggaagctc ttggtgacgc
     9421 aagccaggta aatcagaccg atagcagccc agatcagacc cagaaccatt gagctttctt
     9481 ccaggttaac ccacagcgca ccaacggtca gcgcaccaca catcggcagg aacagatact
     9541 ggaagtgatc tttcagcgtc ttgttacgct tctcacggat ccagaactgc gagatgaccg
     9601 acaggttaac gaaggtgaac gccaccaacg caccaaagtt aatcagcgcc gtagccatta
     9661 ccaggtcgaa gttgattgcc agcagggcaa tcgcgccaac caggatgatg ttcattgccg
     9721 gagtacgcca tttcgggtgt acataaccga agaagctttt cgggaatacg ccgtcacgac
     9781 ccattacgta catcagacgc gcaacacctg cgtgcgccgc cataccggac gccagtacgg
     9841 taatggtgga gaagatcagc gcaccaacct ggaatgcttt acctgccacg tacagcatga
     9901 tttcaggctg tgacgcatcc ggatctttaa agcgagagat atccgggaag tacagctgca
     9961 ggaagtaagt tgcaaagatg aagatcatgc cgccaatcag cgcggtcagg aaaatcgcac
    10021 gcgggattac gcgctctgca tctttggttt cttccgacag gttgctgatg ccgtcaaagc
    10081 cggtaaagga gaagcacagg attgtcgccc cggtaatcat cgggataaca tgcgcatcgc
    10141 cagaccagaa cggacgagtg ctcgccagcg taccagcgcc ttcaccttca aatacgccat
    10201 aaacaaccat gcccagaatc accgcgatca gcactacctg caacacgacg attacagtgt
    10261 tgaagttcgc tacggatttc agactacgca ggttaaaggc ggtcataaag gccaccagcg
    10321 ccaccacaaa catccacgat gggatggaag gcaccagagc ttcaaaataa attttcgcca
    10381 gcagaatgtt gatcatcggc gcgaacagat agtcgagcag agaagaccaa cccaccataa
    10441 agccaaccgt cgggctaatg gatttctggg cgtaagtgta tgcagagcca gcagaaggat
    10501 agcggcgaac cagcttcccg tagctcagag ccgtaaacag gatcgcaatc aatgcgaacg
    10561 cataggctgt cggcacatga ccatccgtga ggcctgaaac gataccaaaa gtatcaaaca
    10621 gcgtcatcgg ctgcatatag gcaagaccca tcattacaac cggaactaac gtaagcgttt
    10681 tacgcaattc cacgcgagag gtgtttggag taacgttatg cgacatggtc attctccttt
    10741 acggtgataa ccgtcgcgta agcaaaaaat tgccccattt ttttggattc ctcagcgaca
    10801 acaactgtcg atttttagta aatatctatc cggtacgaag cccggcctct tggtatgaat
    10861 gattggtttg aagcaaaaaa taaccgacgc tgatgaaacg tcggttttta gtcatttttt
    10921 gacagcggcg cattgtgcct aaatgggggg gaaatgacaa gagaatgaga ggcttgtcat
    10981 aataattttt ctttaaatgg ctgattttcc gtcatcagat tttgcataaa caccggcgat
    11041 cgcactattt gctaaaattt catcccgcca ccagccgctg gcaagccctg cggtctgttc
    11101 gttccagcca atccagacgg gttcaaagag agtttgggcg accactttct tctctattaa
    11161 cgcgccacta tcgagaaaac gttgtgccag ataacggggt aaatagccgc agccgaggcc
    11221 gctaatttgc agctccagct tggttttaaa atcgaaaacg gtaatggctt cttgttcgtc
    11281 gagaagttgt gaggccgtag aagcgcctgc ctgcgcagta tcccccacca caatcgcccg
    11341 atatcgctta ataatacgac ggtttaacgg ctcttcttcc agggctaacg gatgatgagg
    11401 cgcgaccgca aagacttgtt ccagatcgcc caaccgtgaa aaaccaaact cactggaaga
    11461 tggtggctca tgcatcgcgc caacaataat atccgctcgc ccctgagtca gggcatccca
    11521 ggaaccaccg agtacgccat tgataaactt caggcgcgtc acgctatgat gttgataaaa
    11581 agcttcaatc agtggcgcaa gcagagaaaa aggaaacgtg tcgtccacgc caatcaccag
    11641 ctcgttttcc cagccttcat gcagtttgat cgcctgcttt tccagttctc gcacggtatg
    11701 cagaacttcc cgccctttct ctaataacat ttttccggta cgggtgaatt tagcgcggtg
    11761 accgctacga tcaagcaatt gaatattaag gtcgctttcc agcttgtgaa cggtgtaact
    11821 cagagcggac ggcgtcttat agagtttggc cgacgccgcc gcaaaactgc cttctttttc
    11881 taaagcatcg aggatcatca acacatccag cagtggtttc atacacgccc ccttgcagtg
    11941 catgcggcgt cctgctggcg tgatcgttta ctccagcggc attaccagcg gatcgggata
    12001 ctggtattca aatcccagtt cattacaaat ccgactgcca tcaataatct tacctttgcc
    12061 gctgtccaga ctatttctga actgcggagg ctccagcccc agtaaacggg ccatctgcgg
    12121 atagaaaaca ttacgcgcag ggtgagctgg cgcacatata ttatagatgt gtccgccttt
    12181 aggtgcctgt aacaacagag tgatagcgcc aataacatct tctaaatgga ctaaattaac
    12241 accatgttca ccatcaggcg cggtttttcc ggcaaagaag cgtccgggat gacgtcccgg
    12301 tccgaccagc cccgcaagac gcagaatatc gaccgaagta ccgggtaaat tgtgcagcca
    12361 gtcttcgagt tcttctaata ctcgtccact gttggtcacc ggattacgcg gggtggtttc
    12421 tttcaccgtg ccttgcgcgt cgccatagac agatgttgag ctggtgaaaa taatgcgggg
    12481 aatacgatgg gccagcgcgc tatccactaa ctcttgtacc gcttgtaaat agaactcatc
    12541 gccggggccg ctacgacgtg ccggaagcgt aatgaccagc gcatcgacat ccatcagggc
    12601 atccagatcg tcagaatcgc aaactaactc aggctccatg cgaagcagat agctatcaat
    12661 gccactcatt cgggacgctt cgacaccatc ttgtgtggtt ttactcccgg tgacttgcca
    12721 gcctcgcgct gaaagtgaca tcgccagcgg catgcctaac caccctaacc cgacaattgc
    12781 gacctttttc atccgttatc tcctgataca ccttagatct ataaggctac gctagcgtat
    12841 caaaactgac aattcattct atgaatgaat ctgttcaata atgataacga catgctgcaa
    12901 tgagcagtga atcgtcggta accgcgtata ccagacggtg ctcctctgta atgcgtcggg
    12961 accagaaacc tgacaaatta tgtttcaggg gttctggctt ccccttacct tcaaatggcg
    13021 ttctgcgggt atctttgata agttcattga tctttttaac aattcgctta tctgtctcct
    13081 gccagtacag ataatcatcc catgattcct cagaccagat tagtttcact caataatgtc
    13141 cttttctgtt cctttgcctg atttcaggct atcgattgag tccatcaatc tccgggcgtt
    13201 agcgggggag cgcagtagat aagccgtctc ttccagcgag ttgtattctt cgagtgacat
    13261 cagaacacaa gcctctccat tctgacgagt aataaggatc ggggcatgat cttcaacggc
    13321 tttcatcatt gttgccgaca aattctgacg cgcttcgctg tagctaattg tacgcatgtc
    13381 aatctcctct tttgtacagt tcattgtaca atgatgggcg ttaattaact atttattaat
    13441 tagtttgtag atcaaggtat tgtcagtgag acgaaaatcc aggcttcgct atttttggtg
    13501 ccgtcagctt agaggacagt cctcttagcg ccctcctttc cccgctcatt cattaaacaa
    13561 atccattgcc ataaaatata taaaaaagcc cttgctttct aacgtgaaag tggtttaggt
    13621 taaagacatc agttgaataa acattcacag agacttttat gacacgcgtt caatttaaac
    13681 accaccatca tcaccatcat cctgactagt ctttcaggcg atgtgtgctg gaagacattc
    13741 agatcttcca gtggtgcatg aacgcatgag aaagcccccg gaagatcacc ttccgggggc
    13801 ttttttattg cgcggttgat aacggttccg acaggtttaa agaggaataa caaaatgaca
    13861 gacaacactc gtttacgcat agctatgcag aaatccggcc gtttaagtga tgactcacgc
    13921 gaattactgg cgcgctgtgg cattaaaatc aatcttcaca cccagcgcct gatcgcgatg
    13981 gcagaaaaca tgccgattga tattctgcgc gtacgtgacg acgacattcc cggtctggta
    14041 atggacggtg tggtagacct tgggattatc ggcgaaaacg tgctggaaga agaactgctt
    14101 aaccgccgcg cccagggtga agatccgcgc tactttaccc tgcgtcgtct ggatttcggc
    14161 ggctgccgac tttcactggc aacgccggtt gatgaagcct gggacggccc gctctcctta
    14221 aacggtaaac gtatcgccac ctcttatcct cacctgctca agcgttatct cgaccagaaa
    14281 ggcatctctt ttaaatcctg cttactgaac ggttctgttg aagtcgcccc gcgtgccgga
    14341 ctggcggatg cgatttgcga tctggtttcc accggtgcca cgctggaagc taacggcctg
    14401 cgcgaagtcg aagttatcta tcgctcgaaa gcctgcctga tacaacgcga tggcgaaatg
    14461 gaagaatcca aacagcaact gatcgacaaa ctgctgaccc gtattcaggg tgtgatccag
    14521 gcgcgcgaat caaaatacat catgatgcac gcaccgaccg aacgtctgga tgaagtcatc
    14581 gccctgctgc caggtgccga acgcccaacc attctgccgc tggcgggtga ccaacaacgc
    14641 gtagcgatgc acatggtcag tagcgaaacc ctgttctggg aaacgatgga aaaactgaaa
    14701 gcgctgggtg ccagttcaat cctggtcctg ccgattgaga agatgatgga gtgatcgcca
    14761 tgagctttaa cacaatcatt gactggaata gctgtactgc aaagcaacaa cgccagctgt
    14821 taatgcgccc ggcgatctcc gcttctgaaa gcattacccg cactgttaac gatattctcg
    14881 atagcgtgaa agcacgcggt gatgacgccc tgcgggaata cagcgcgaag tttgataaaa
    14941 ccacggttac cgcgttgaag gtgtctgctg aggaaattgc cgccgccagc gaacgcctga
    15001 gcgacgagct aaaacaggcg atggcggtgg cagtaaagaa tattgaaacc ttccacactg
    15061 cgcaaaaact gccgccggta gatgtagaaa cgcagccagg cgtgctttgc cagcaggtca
    15121 cgcgcccggt agcttcagtt ggtttgtata ttcctggcgg ctccgccccg ctcttctcaa
    15181 cggtattaat gctggcgact ccggcgcgta ttgcaggttg taataaagtg gtgctgtgct
    15241 caccgccgcc gattgccgat gagatccttt acgcggcgca gctgtgcggt gtgcaggacg
    15301 tgtttaacgt cggcggcgca caggccattg ccgcgctggc gtttggtact gaatctgtgc
    15361 caaaagtgga caaaatcttc gggccaggca acgcctttgt caccgaagcg aaacgtcagg
    15421 tgagccagcg tctggacggt gcggctatcg atatgcccgc aggcccgtcg gaagtgctgg
    15481 tcattgctga cagcggcgct acgccggatt tcgtggcttc tgatttgctc tctcaggctg
    15541 aacacggccc ggactcacag gtgattttac tgacgcccga cgccgatatg gcgcgtcgcg
    15601 ttgccgaggc tgttgaacgc cagctggcag aactgcctag agctgaaacc gcccgtcagg
    15661 cactgaacgc cagccgcctg atcgtgacta aagatttagc gcagtgcgta gagatctcca
    15721 accagtacgg cccggagcac ctgatcatcc agacccgcaa cgcccgcgat ctggtcgatg
    15781 gcatcaccag cgccggttcg gtatttcttg gtgactggtc accggaatcg gcaggtgatt
    15841 acgcctccgg aaccaaccat gttctaccga cttacggtta caccgccacc tgttccagcc
    15901 tcggcctggc ggatttccag aagcggatga ccgtgcagga actgtcgaaa gtaggtttct
    15961 ccgcgctggc ttcgaccatt gaaacactgg ccgccgccga gcgcctgacc gcccacaaaa
    16021 atgccgttac tttgcgtgtt aacgccctta aggagcaagc atgagcaccg tgactattac
    16081 cgatttagcg cgtgaaaacg tccgcaacct gacgccgtat cagtcggcgc gtcgtctggg
    16141 cggtaatggc gacgtctggc tgaacgccaa cgaatatccc acagccgtgg agtttcagct
    16201 tactcagcaa acgctcaacc gctacccgga atgccagccg aaagcggtga ttgaaaatta
    16261 cgcgcaatat gcaggcgtaa aaccggaaca ggtgctggtc agccgtggcg cggacgaagg
    16321 tattgaacta ctgattcgcg ctttttgcga accgggtaaa gacgccatcc tctactgccc
    16381 gccaacgtac ggcatgtaca gcgtcagcgc tgaaaccatt ggcgtcgagt gccgcacagt
    16441 gccgacgctg gaaaactggc aactggactt acagggcatt tccgacaagc tggacggcgt
    16501 aaaagtggtc tatgtttgca gccccaacaa cccaaccggg caactgatca atccgcagga
    16561 ttttcgtacc ctgctggagt taacgcgcgg taaggcgatt gtggttgccg atgaagccta
    16621 tatcgagttt tgcccacagg catcgctggc tggctggctg gcggaatatc cgcacctggc
    16681 tattttgcgc acactgtcga aagcttttgc tctggcgggc cttcgttgcg ggtttacgct
    16741 ggcaaacgaa gaagtcatca acctgctgat gaaagtgatc gccccctacc cgctctcgac
    16801 gccggttgcc gacattgcgg cccaggcgtt aagcccgcag gggatcgtcg ccatgcgcga
    16861 acgggtggcg caaattattg cagaacgcga atacctgatt gccgcactga aagaaatctc
    16921 ctgcgtggag caggtttttg actctgaaac caactacatt ctggcgcgct ttaaagcctc
    16981 cagtgcagtg tttaaatctt tgtgggatca gggcattatc ttacgtgatc agaataaaca
    17041 accctcttta agcggctgcc tgcgaattac cgtcggaacc cgtgaagaaa gccagcgcgt
    17101 cattgacgcc ttacgtgcgg agcaagttta atgagtcaga agtatctttt tatcgatcgc
    17161 gatggaaccc tgattagcga accgccgagt gattttcagg tggaccgttt tgacaaactc
    17221 gcctttgaac cgggcgtgat cccggaactg ctgaagctgc aaaaagcggg ctacaaactg
    17281 gtgatgatca ctaatcagga tggtctggga acacaaagtt tcccgcaggc ggattttgat
    17341 ggaccgcaca acctgatgat gcagatcttc acctcgcaag gcgtgcagtt tgatgaagtg
    17401 ctgatttgtc cgcacctgcc cgccgatgag tgcgactgcc gtaagccgaa agtaaaactg
    17461 gtggagcgtt accttgctga gcaagcgatg gatcgtgcca acagttatgt gattggcgat
    17521 cgcgcgaccg atattcaact cgctgaaaac atgggcatta ctggtttacg ctatgaccgc
    17581 gaaaccctga actggccgat gattggtgag cagctcacta aacgagaccg ttacgcccat
    17641 gtagtgcgca acaccaaaga gacgcagatt gacgttcagg tgtggctgga tcgcgaaggt
    17701 ggcagcaaga ttaacaccgg cgttggcttc tttgatcata tgctggatca gatcgccacc
    17761 cacggcggtt tccgcatgga aatcaacgtc aaaggcgacc tctatatcga cgatcaccac
    17821 accgtcgaag ataccggtct ggcgctgggc gaagcgttaa aaattgccct cggcgataaa
    17881 cgcggtcttt gtcgctttgg ttttgtgcta ccgatggacg aatgccttgc ccgctgcgcg
    17941 ctggatatct ctggtcgccc gcacctggaa tataaagccg agtttaccta ccagcgcgtg
    18001 ggcgatctca gcaccgagat gatcgagcac ttcttccgtt cgctctcata caccatgggc
    18061 gtgacgctac acctgaaaac caaaggtaaa aacgatcatc accgtgtaga gagtctgttc
    18121 aaagcctttg gtcgcaccct gcgccaggcc atccgcgtgg aaggcgacac cctgccctcg
    18181 tcgaaaggag tgctgtaatg aacgtggtga tccttgatac tggctgcgcc aatctgaact
    18241 cggtgaagtc tgccattgcg cgccacggtt atgaacccaa agtcagccgt gacccggacg
    18301 tcgtgttgct ggccgataaa ctatttttac ccggcgttgg caccgcacaa gcagcgatgg
    18361 atcaggtgcg tgagcgcgag ctgtttgatc tcatcaaagc ctgtacccaa ccggtgctgg
    18421 gcatctgctt agggatgcaa ctgctggggc ggcgcagcga agagagcaac ggcgtcgact
    18481 tgctgggcat catcgacgaa gacgtgccga aaatgaccga ctttggtctg ccactgccac
    18541 atatgggctg gaaccgcgtt tacccgcagg caggcaaccg cctgtttcag gggattgaag
    18601 acggcgcgta cttttacttt gttcacagct acgcaatgcc agtcaatccg tggaccatcg
    18661 cccagtgtaa ttacggcgaa ccgttcaccg cggcagtaca aaaagataac ttctacggcg
    18721 tgcagttcca cccggagcgt tctggtgccg ctggcgctaa gttgctgaaa aacttcctgg
    18781 agatgtgatg attattccgg cattagattt aatcgacggc actgtggtgc gtctccatca
    18841 gggcgattac ggcaaacagc gcgattacgg taacgacccg ctgccgcgat tgcaggatta
    18901 cgccgcgcag ggtgccgaag tgctgcacct ggtggatctg accggggcaa aagatccggc
    18961 taaacgtcaa atcccgctga ttaaaaccct ggtcgcgggc gttaacgttc cggtgcaggt
    19021 tggcggcggc gtgcgtagcg aagaagatgt ggcggcgtta ctggaagcgg gcgttgcgcg
    19081 cgtagtggtc ggctccaccg cggtgaaatc acaagatatg gtgaaaggct ggtttgaacg
    19141 cttcggtgcc gatgccttag tgctggcgct ggatgtccgt attgacgagc aaggcaacaa
    19201 gcaggtggca gtcagcggct ggcaagagaa ctcgggcgtt tcactggaac aactggtgga
    19261 aacctatctg cccgtcggcc tgaaacatgt gctgtgtacc gatatctcgc gcgacggcac
    19321 gctggcaggc tctaacgtct ctttatatga agaagtgtgc gccagatatc cgcaggtggc
    19381 atttcagtcc tccggcggta ttggcgacat tgatgatgtg gcggccctgc gtggcactgg
    19441 tgtgcgcggc gtaatagttg gtcgggcatt actggaaggt aaattcaccg tgaaggaggc
    19501 catcgcatgc tggcaaaacg cataatccca tgtctcgacg ttcgtgatgg tcaggtggtg
    19561 aaaggcgtac agtttcgcaa ccatgaaatc attggcgata tcgtgccgct ggcaaaacgc
    19621 tacgctgaag aaggcgctga cgaactggtg ttctacgata tcaccgcttc cagcgatggc
    19681 cgtgtggtag ataaaagctg ggtatctcgc gtggcggaag tgatcgacat tccgttctgt
    19741 gtggcgggtg ggattaaatc gctggatgac gccgccaaaa ttctttcctt tggcgcggat
    19801 aaaatctcca ttaactcccc tgcactggcg gacccgacgt taattactcg cctggcggat
    19861 cgctttggcg tgcagtgtat tgtggtcggt attgatacct ggtacgacgg cgaaaccggt
    19921 aaatatcatg tgaatcaata taccggcgac gaaagccgca cccgcgtcac tcagtgggaa
    19981 acgctcgact gggtacagga agtgcaaaaa cgcggtgccg gagaaatcgt cctcaacatg
    20041 atgaatcagg acggcgtgcg taacggttac gacctcgaac aactgaaaaa agtgcgtgaa
    20101 gtttgccacg tcccgctaat tgcctccggt ggcgcgggca ccatggaaca cttcctcgaa
    20161 gctttccgcg atgccgacgt tgacggtgcg ctggcagctt ccgtattcca caaacaaata
    20221 atcaatattg gtgaattaaa agcgtacctg gcaacacagg gcgtggagat caggatatgt
    20281 taacagaaca acaacgccgc gaactggact gggaaaaaac cgacggactt atgccggtga
    20341 ttgtgcaaca cgcggtatcc ggcgaagtgt taatgctggg ctatatgaac ccggaagcct
    20401 tagacaaaac catcgaaagc ggcaaagtca ctttcttctc gcgcactaaa cagcgactgt
    20461 ggaccaaagg cgaaacgtcg ggcaatttcc tcaacgtagt aaatattgcg ccggactgcg
    20521 acaacgacac gctactggta ctggcgaatc ctatcggacc aacctgccat aaaggcacca
    20581 gcagctgctt cggcgaaact gctcaccagt ggctgtttct gtatcaactg gaacaactgc
    20641 tcgccgaacg caaatcagcc gacccggaaa cctcctacac cgccaaactg tatgccagcg
    20701 gcaccaaacg cattgcgcag aaagtgggtg aagaaggggt ggaaaccgca ctggcagcga
    20761 cagtacatga ccgctttgaa ctgaccaacg aggcatctga tttgatgtat cacctgctgg
    20821 tgttgttgca ggatcaaggg ctggatctcg gagaagtgat tgataatctg aagaatcggc
    20881 attaacgcgt tggcccccgc agcaacggcg ggggtagcat ctctcaggat ttgctttcca
    20941 gcaatgtagt gtagagattg acataggcgt caatcatatg gtcggcagta aacatctctt
    21001 caaaacgacg acgcgagttt tcgccatagc ggttggaggt ttcctcgtta ttccagagct
    21061 cattcatcgc ctccaccagc gcctggctat cattcggcgg aatcacgcaa ccactcactt
    21121 tgtcctggtt aatgaaagag gtacctgtac caatctcaca agagatcagt ggccttgcga
    21181 agcgtgcgcc ttccaataac gtaataccaa acgcctcaga gcgcagatgc gaggggaata
    21241 ccacgccccg gcagagctgg aagagaatgt acttatcttc gtcgttgagc atgccggtaa
    21301 acatcacatt gctcagcccg cgctgctgcg cttcacgccg cacttccgat tccagcggcc
    21361 cgccccctac aaccaccact ggcagtcggc tacgctcagc ggcatccatc agaatatgca
    21421 gccctttgta gtagcggaaa gtgccgacga agagaaagaa cttatcgccg acagtttccc
    21481 gccagtgcgc gaccctctgc ggatcgtgct gcacgtcctg ctgttccaga ccaaacggga
    21541 tcaccaccgt tttatccaga tattttttca gggtctggct ggaagccaca taattgggcg
    21601 acgaggcaac gatgcaatct acgccgctga gaaatcgctc ctgcagcggc tggtacagct
    21661 tcattaaccg tttttgtttc actatatcag agtgataggt caccacagtc ctggcgtcag
    21721 gccgcgccga aagatgcagc atatccataa agggaaacgg aaaatggtag ttgatgatat
    21781 cgtagtcatc tttaatcagc ttaaaacgct ttaacgcttt cagcgaaaac ggcgtggagg
    21841 caatttcaaa aagctgttta ttataaatga cccgatgatc ttcgtaagcg acaggacctg
    21901 tatctttgtc cgggctaaaa gtgaaaacat cggctgcgat tccccggcgg gcgcagccct
    21961 gacttagctg ataaattacc tgctcaatac cgccgtaggt atcgggatag taagtcttat
    22021 agacgtgtag aactctcaac tgacaccctt agagtaattt ataggcgtta atggtctgtg
    22081 tcgcacagtt ctcccacgaa aactgtttcg cctgagcaag accgcgcgcg gtggcgattt
    22141 cccgccagct atcatcttgc aggctctgca aaatttgcgc gctaatcgcg tctatatcat
    22201 taggatcggc aacgaggccg gcatcgccaa caacctcagg caaagaggtg acattggagc
    22261 atactaccgg cacaccgcaa gacatcgctt caagaatagg taaaccgaat ccctcgtaga
    22321 aggagggata aacaaagact ctggccgctg cgtacagata cggcaggtct tcatccggaa
    22381 catatccgag gtaacggatc cagccttccc gagtaccgag ctcgactaac tgccacagca
    22441 catcgtcttc ccagccgcga tagccgctaa ggattagcgg atagcgcatg cggatctcca
    22501 tcggtagcag ctgataggca tgcagcaggc ctcggatatt tttacgtggc tccatagtgc
    22561 cgatatatag cgcgtaggcc tgccacgcca gctgatattt ctgcagtacc ggcagacact
    22621 ctgccgggct gcgtgggata tagtcactgc tgcaggctag cttggtggtt acgatccgct
    22681 cctccggata gttgaacaag cggataattt cactgcgcga gaaatcagaa acggtcagga
    22741 tcagctttgc cgaatccaga ctctcatgca gggacttctc catatagcga acccgatctt
    22801 ttggatgata ttccgggcag gtaaaaatgg atatgtcatg aaacgtggtc acggcgcgtt
    22861 ccagtttatg cggcagataa aaattggggc catggtagat ataatcctta tagtcgcgca
    22921 atgcccacgc ctggcgccgc ggatgcagca agcgataagc ctcaatcaac agcgtctgtc
    22981 ggcgtagaaa cgccgacaga cgaccatgat tgctggcttt ggtatcgctt ttattctcca
    23041 ccaaagggat ctgttctata aacgacgcac cgtgaaatag ctttaattct tcaatttcgc
    23101 gggcgaccgc cagccgctta accagctcca gggaataccg accgatgccc gttaatgggt
    23161 atttaattgg ctcagtagca aaaataattt tcataataaa tgacacatta tctaacccct
    23221 cttgtattca aaggcaaaaa atacaagaga gatattttta tttaaaatat ttagctttag
    23281 ctaagccttg acacatatta accagacggc gtgaaacagc ttgataatca tgttgttccc
    23341 gccatgcatc ggcacgttgt tgagtcctgg ttgcccaaga gttctgttca cggatggaat
    23401 tcaggatccg gtcaatcccc tgactgatat catcgacgct gcatccatca aatttaaaga
    23461 cggcatcgtc caaatcatca aatatcgcca ggggcgttac cgcaacaggt ttttgagtcg
    23521 ccataccata acgtaccgcc ccgctagcag actccccagt attctgataa gcaaaaatca
    23581 gaagatcggc ttctgaaagc aaccgcagac tctccgcatc aggtaggaaa tcattatgca
    23641 tctcaatcag atcggtaaca cctaaccgct gagcagcagc tttaagctct gccaccagat
    23701 cgcgtgactc cccaacagga tactctgcgt tcaccagtcg taaacgaacc ggtttaccgg
    23761 cttgcttgag tctatggacg gattctacta gttccatcag gcccttatgc ggtaagcaga
    23821 agccatagct cgcaattagc ggtaaagact gctgttgacg tgtgacgctc gctgcggagt
    23881 agttgataac accgtgcggg aataaagcaa cattcgcagt taagcctaaa tctttaaggc
    23941 ggttcatatc ggcaatcgaa tgcaccaaca accggtcgca aagtgccagc gcctctttca
    24001 tttcagcaag acggaaattc cagctcggct ctttttccag cggatccaca gttgagtgca
    24061 tcgtcataac aactgaacga ccggcgtcat gctggcgacg aataaacacc gacagttctc
    24121 gatgattaaa gaatccatag ttgaattgga tcacaatgac atcgagtttc agagcatcaa
    24181 tgtgtggctg gaggttttcc agatagttgc tctctttacc tacaatccag ttgcgaagta
    24241 caaactcttc gtctgcacac acaagatcgc cagcgctgac ctggggagca aaaacaacat
    24301 ccgcgccatg aggtgcgctt tccaccagat gctgggaata ggttgcgatc ccacatttcg
    24361 tgttccaggt cgtcaaccag ccaatgcgcg cccgatgctg tgcaatatca atatgcgcac
    24421 gcagagtctt gaccgcctgg caagaacgat cagccaccgc tttccaggta aactgctgca
    24481 gaagaagctc gcgaccagca ttggccatgt cacgcagcac tgatttatcg gttgaggctg
    24541 ccgcttttaa tgcatctgtt aagttgtcaa tatccacact ggcccaggct gaggaaaaca
    24601 gaccaaagtg cgtttttacc cgagtgaact gatagtcaac cagccatgaa ttttgtgaat
    24661 taacaaaatc aagttgcccg ctccaattgg tgacgatagc cggtagccca ctcagcattg
    24721 cttcagcaat aggtaaacca aagccttcag cgcaacctgg agcaaccaaa acatcacagc
    24781 tttcataaag ccctttaagc tcggtggctg atatatcctc tttgatcact tcaactttgg
    24841 gatagtctat gaattgagcc tgggcctgag ccagccatgc gtcaatttca ttgtgcggat
    24901 tgttaaaagt cttaatgatt aagataacat tgtcacgacg agtgaacgcc ttcccccaag
    24961 cctgaagcat tgcctgtatc cctttgcgtg ggaaacaaga agagacgtgc aggaaacgga
    25021 atgttccgtg atccacatct tttgtcgtct cggctgggat attgagccaa tggtcacagc
    25081 cattgccaac aacaaatgcg ggcacattca gtccgttatc aatcaatatt ttacgaacat
    25141 gttccgaagt acacagcact ccgtcaagtt cccgattaaa ttcattgatc cacggttgcg
    25201 gaaagcccgt ttcttcccaa gcataacaat gaaggaattt tactttggca tccattttgg
    25261 taacccgcgg tggatagata tttctgctaa gaatatctat cttttcgtta ctcttgcggg
    25321 tctgacattg attataaaat gccagaagat cactattttc cgactgtgcc ataaacgagg
    25381 catctggggc aaaatcacct ggtccttcag tggaatgcaa taaaacctct acaccatcgg
    25441 ctgagagtgc ccggacaaat tcgcggttga ccaacgacag actatatgag ctatcgaatg
    25501 ggccttccac acgccagttc agcgatttat cgtcgatttg ataaagttct gccgttttca
    25561 gattgtaatc aatggccgtt gcgcacaagc gcagatcgcg gtcatctggc tgcccttgtg
    25621 ggatagcaag gatcttctga atcaaagctt caggcaaaac ctgcgcagta ccggtgtctt
    25681 ctaccgcgat cttttcgaaa gcttccagag cagtcaccgc agccttatcc caagagaaat
    25741 tacgcgcttg ctgctgcgct atttctttca gacgcgcgag gaaggtatca tcagtcaaac
    25801 attgcgcgat cttatccctc atggaagaga cagaatacgg gtcgaataat gcctcaggat
    25861 tatcgatgac ttcaggaata ctggtgacat ttgagccaat caccggcgca ccgcacgaca
    25921 ttgcttccag aaccggcaac ccaaaacctt catgtagtga agcaaagatg aacagcttac
    25981 ataggcgata gagctggatc agctcatctt caggcacata accagtgagt accagttcgc
    26041 cctgctgtaa accattacct gacgcaaggg attccagata ctgacgatca ccgatggaaa
    26101 gcttactgac gataaccagt tgatgactgc gacgtaaggc atcactgagc ccggcatagg
    26161 cctcaatcaa ccgtttaaag tttttccttg agtcaaatcc tccgggcgca tacaacatga
    26221 actcgcgctg aataccgtaa tggccaagga cggtctcttt ttcgctcgct gccacctccg
    26281 ccatacaaaa ctgagaatcg actgcggctg caatattctg cacatgatcg ccctgtaaat
    26341 gcagatgctc aatcgcttcc tgtgcggtat aagcagagtt agtcaacaaa aggtcagcgt
    26401 tttttaacca ctcaactttc tgtaagtagt agggtttgta tacatcgtcc tgcagatagg
    26461 tttccgcctg cacgaggggg ataagatcgt ggtgcagtac ggctacttta tactgacgac
    26521 taaatttgtg taccgatgta gccgcatcgt cgacatgacc ttcaaacaaa ctcgtaatga
    26581 aaacgacatc tggacacaat gattcaagaa acgcttcccg aatcagttct gcgctctccc
    26641 gacgccattc attaccttgg tccatcgcac gaacagggcc tacggcatgc catacgacta
    26701 tattttctgc cggcaggaga tcggcaaatt gcgccttaat atctgcaatc gactcatcca
    26761 gcatggcgga tagcgcgatg aaaatctcat gccggctgtt atttctgatt atgcctctgg
    26821 cgattgcgat actataacga ccgatgccac gaaagcggct ttccgtctgt gcgccttgta
    26881 aatctatgac aatacgcatc gttatttctc cgtattttta ttttttaatt cgttataaat
    26941 actcatcgcg cgacttgtca tttcttcagt acccacatca tatcttctgg actgcatcat
    27001 gatcgtgtca gattgcacca gcattacgcg ttggaacaaa cgttgtagca atgtatagca
    27061 gccagttttt ctcagaacct taaacagata aaccttagac ttagggtaac gatggaaaaa
    27121 gaccagcgag agcgccatcc ctttgcgcaa tatttttttc gcagccctac gggctcgcac
    27181 tttagcccct tcctgacgta ataaatgacg ttgcaaagac aaccagcgta gtggttgagt
    27241 aatacgccat gaacgactgt tatgtaaatc cgccatttgc tgatgaagct gatggttctg
    27301 atcgataaca tgactcagat cgtcaacctc accttgcaac gtctgaatag tctctgacat
    27361 ttggcttatc tgttgcatat aggtttggtt caacgtctcc agccgtgaga caacggacga
    27421 aaactgttgg cgcaaaatcg catcgtaacg gttgctcaga gcatccagcg tcagaccgta
    27481 ctgctgggta aacagggtgt caaagcgttc aagaatatct gttggcgctg ctttctgagc
    27541 aatgatgctg tagtcggggc tcaccccttt gagtacatcg accaaattaa cggctgcatc
    27601 cggagattga agaacctctt tttcctgcag acgaacggta attgctcggt taaaaccata
    27661 atgaataggt aaaaactcaa gcagtggcgg tggcagagga tgattatgcg ttggatccat
    27721 ataaaatgaa caggtgccga cgcttacatt ctccgggttc ggcgtttcga ggatcagcaa
    27781 accacctggt ttcagcaccc gtagggtatg catgacgagc tgctgcagga cctcaaaagg
    27841 caaatgctca gcaatatgaa aaccggtcaa cgctatcagg ctctgatccg cctgactttg
    27901 cagaaactgc agacaatcca ttttctgcac attcagtccg gcctccctgg cgcgcgccag
    27961 catgccatca tcgagatcga cgccgatgtt tgcaatgcca ttttcagtca ggatctccaa
    28021 ccattcgcca cgtccacaac caatatccgc aatcatgcca tcaggataaa tgtccttcag
    28081 acctgcaaga aaaggtaaat aaaaactcaa gcggcgcttg atttcttcaa ccgaacctct
    28141 gtgtcgttct tcaaatgaac gataaaacga cgaacccatt aagaaatctc cagttcaggc
    28201 ggcaaccagg acacgccgac aaactcttgt tgttccgtgt taacgacgtt gaataccacg
    28261 gccagatcgc gccattcata gtttttgccg aggtgcgtac tggaagtatg caacgcgaca
    28321 gcgacagaat aggagccaac ccccaatctc gcatcgaaag aaaataagaa cgaacgcttt
    28381 tctccttttt tcagggaggt gagtgtctga ttgagatggt acgtattggt cccgaaaatc
    28441 ggctgcccaa gtcgatcctt aatcatatat ccgacaacaa gctcaggaat atcgtccttg
    28501 acctcaacgt tgacctgcaa gctgacacga tgccctaccg aaacaaattc agtcacattg
    28561 ccctgttcat cgagaagatg aacctcagag atagtcacct caccagtgcc tgaaacagtt
    28621 tgcgttttac cattatgctc aacttgttta atggactgat tttgtttatc ggccagaaga
    28681 gcattgtaat aatccatcac tgcttcaggt tcaccttcca tttcaatttg gcctttattc
    28741 aataaaatgg cccggtcgca aatgctttgg atcgcttgtt tatcatggga taccagcaac
    28801 agcgtggtcc cttcctgacg aaattttcga atacgctcaa agcttttatg ctggaaatat
    28861 gcatccccaa cagataatgc ttcatcgata attagcacat caggacggat agccgtcgct
    28921 acactaaaag ctaatcgaac ttgcatccca ctggagtaga cgcgcacagg ctgatcgata
    28981 tagtccccaa tctcagcaaa ctcttcaatt tgcggcatca gttcagttat tttctctgac
    29041 gataacccca acagttgccc agacatataa acattctgcc ggccagtgaa atcagaatga
    29101 aaccccatcc ccaattcgag taatgcagcg acacgtccgg agatttcaat ttctccagtc
    29161 gtcggcctgg acgtcccggt tatgagttta agcagggtac tcttgcctgc accgttgata
    29221 ccgataatac cgacagcctc gcccggagcg acttcgaaat taatctcgcg gaggatccat
    29281 ttcaaattat ggcgttttgt attcagaggg gataaccatt cgatcagtct cccggtcttt
    29341 gagtgatact ggcgatacgc cttaccgaca ttatttactc tgatataact cattataatt
    29401 catccaccat atccgccgca tgcttgcgga acatcctgaa accgatgacg cagaaaataa
    29461 tggcgagagc caatactggc catagcgaat accagttggg ggccagatga taggcgaaga
    29521 tagactgata agattgcatg atccgagtca tcgggttata catcatcaga ttttttgccc
    29581 atgcaggtaa tgaattcagt acataaacaa tgggtgtgaa ccaaaaccag aattgcagcg
    29641 caacgccaac cagttgcccc acatccctga aaaagacgtt catgacacca aggatcatcc
    29701 ccagcccacc ggcaaacagg atctgcaaaa gcaggaccgg tatcaccgag agaaagagcc
    29761 agccggggaa gttaccggtg acaatgataa aaattagaaa cagactgaaa ataatcgcga
    29821 aatttagcac cgccgataac gtcacgatga tcggcagaca gattttcgga aaactgagtt
    29881 tcttgatcag attagcattg ttaataaata cgctctgacc tttatccagc atctcagtaa
    29941 ataatcccca ggtcagtacc ccggaacaga gataaatact ataggcaaac gacccggtat
    30001 tatcgggcat tcttgccttc atcacctcgg aaaaaaccag ggtatagacc agaatcatag
    30061 agagcggttg taaaacgagc caaagtgcgc ccagcatact agtttgatag cgcgcctgaa
    30121 aatcacgttt aacactgctc cagataaatc cccgataacg ataaatcgtc gttagtaaat
    30181 ctctcacctt attccccgct taacaggtgt aacagctcgg tcgtttttgc attcattaac
    30241 gcagtatccg ctctggactc cacgttcaga cgcaccaccg gctccgtgtt ggacgtgcgc
    30301 aggttaaagc gccactcagg gtattcaata ctgataccgt ccgttgtgtc gatgtgtgcg
    30361 gccgccggct catactgtgc ccgga
//
LOCUS       DADXDL010000063        29703 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.063, whole genome shotgun sequence.
ACCESSION   DADXDL010000063 DADXDL010000000
VERSION     DADXDL010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 29703)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29703)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29703
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.063"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            209..2518
                     /locus_tag="IRB70_003111"
     CDS             209..2518
                     /locus_tag="IRB70_003111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TerB N-terminal domain-containing protein"
                     /protein_id="HBC0632994.1"
                     /translation="MELWIFIVAIYLIYILFFKKKKTKSAGSYTSAPVKAPPKEWLAN
                     NKKNQSVMQNEDSEDDNLATFTLSGGRNVEYSITATQRQNFSKTTGALARWIFPGEMI
                     TISGIEVTGGHFYLGQRMKPAGHNSGGYYDGNNEASLVDDTLKIYPTPYIYEDSSLGY
                     WPSFSSLSPEARGAYLSWLASDRCDTSCPIGYVFIYLYGLERRALVDSRDNNISDDEF
                     YSLFKEICRLRSVFNENRSFRNYSSQLLEAMSILRPNENLAAALNDDSEFSNSMQFRL
                     ILAKTVDTGAPVPADLALTWVTNHAEYSLRTPARRCAKEFAALFKRRYTLKYGEGMVV
                     KPNKARLRLDYTPASPSLRGIRLPVPDLPDPGALKGPVQKLMAIADICTGELDAYSRY
                     LGRKGTSANDTAAILLLPSEIVNESAEKILSTFKHWADDAIRSKGGIVSVADYWSHMN
                     ATCPAKINKKEADLMQAFAQKMGYCLAPDPYHHHVKADVDGVLVLFPAGERGRFSPSP
                     EFITAVLTLRLGSVVALIDNSLDQAEQKVLENAINNNASFSDDEKRSLHAYLTWQLHT
                     PANMTGMKSRIELLGAAEKSAVGKVIVSVACSDGRITPAEIKQLEKIYTSLGLDPSSV
                     SSNIHQHSATETALVSSVPANQSTAGFTLDANVLARHESATDDVRKLLNSIFTEEEPE
                     QPESAPASLTGEGGLDSAHSQLYRRLLEKEQWSRKEATELCSNWNLMLGGALEVINDW
                     SYAVVDAPVLEDADDHIWIDLEIAKELEG"
     gene            2522..3838
                     /locus_tag="IRB70_003112"
     CDS             2522..3838
                     /locus_tag="IRB70_003112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000117530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBC0632995.1"
                     /translation="MSVTRIRVKERDAIIQSLKSGVTPRIGIQHIQVGRVNEITALHQ
                     DIERIADGGASFRLIIGEYGSGKTFFLSVVRSIALEKKLVTVSADLSPDRRIHSSGGQ
                     ARNLYSELMKNMSTRNKPDGNALLSVVERFVTEARKEADANGSLVSSVIHKRLAALSD
                     MVGGYDFAKVIDAFWRGHEQDNETLKSNAIRWLRGEYTTKTDARNDLDVRTIISDASF
                     YDSLKLMSLFVRQAGYAGLLVSLDEMVNLFKLNNTQARTANYEQILRILNDCLQGSAE
                     NIGFILGGTPEFLFDPRKGLYSYEALQSRLAENRFAQKAGVIDYSSPTLHLASLTPEE
                     LYILLKNLRHVYAGGDPANYLVPDDALTGFLHHCSKTIGDAYFRTPRNTIKGFLDMLA
                     VLEQNRTMNWQTLIEGVAIEEDKLSDMDDAIVEESDDDDGLANFRL"
     gene            3835..6033
                     /locus_tag="IRB70_003113"
     CDS             3835..6033
                     /locus_tag="IRB70_003113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001403205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBC0632996.1"
                     /translation="MSSAYNSLDPRVRKWVYKQGWSSLRPLQESSIPAILARDRDVLI
                     SAGTAAGKTEAFFLPACSAIADLTGGFGIIYISPLKALINDQHRRLESLGEALEMQVT
                     PWHGDVPQSKKKKARTTPSGILLITPESLESLLINSLGWLKQAFSSVAYIVIDEFHAF
                     IGSERGIQLLSLLNRIDHVLGRQLNPVPRVALSATLGELEKVPELLRPDKRLPCETVT
                     DSNSKATLQVQVKGYLERVPEKGEELQSSAEQLVCADIFRLCRGDSHLVFANSRKRTE
                     SIAATLSDMCEANVVPNEFFPHHGSLARELREALEARLQKGNLPTTAVCTMTLELGID
                     IGKVQSVIQVTPPHSVSSLRQRMGRSGRRDSPSVLRMLITEPELTATSSIVDHLRLQL
                     VQAMAMIRLMISKRWFEPADIRQKHYSTLLHQILAITAQWGGVRADQLWSQLCQTGPF
                     RNVDINDFKSLLKHMGTCGLLTQLTSGEIVVGAEGEKLTNHYTFYAVFNTPEEFRIVT
                     GNRTLGTVPVDSPLLPEQHIIFGGRRWKVTEIEVEKKVIYVETTKGGQPPLFSGTGMS
                     VHDVVRQEMLTIYRENDYRIAVGNKRVDYADAAARSLFAEGSDNFQRYNLQNDCFIAS
                     GQNCYVIPWMGDKIVNTITSLIIRCGFKASSFAGVIEVEDSGVASVQRALKKMLLSGL
                     PSEFELAAVVPDKYLDKYDEYLPETLLAKGYGAQAYDIEGTCIWLQKHLQ"
     gene            complement(6081..6404)
                     /locus_tag="IRB70_003114"
     CDS             complement(6081..6404)
                     /locus_tag="IRB70_003114"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632997.1"
                     /translation="MNNRYWMISFHKNTRNLTVRSVPKKDIAHNIELIIRPLNIPIEK
                     FLSIEYTNVEGIPLTSRRITIMGLKPGPKPIAKSTGKPDQRRRDNKDTPGNTPGLKPS
                     KSTGK"
     gene            complement(6469..7113)
                     /locus_tag="IRB70_003115"
     CDS             complement(6469..7113)
                     /locus_tag="IRB70_003115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001376509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0632998.1"
                     /translation="MMKKGMANSISMTWQLLCDDHGFTREHYNQLKKFSPEALREIIA
                     EIACCHPSTSILLRNKWLTPPEDIPEQVTREYERRIQNCPSFRSEKEAESWLNELFFA
                     VIAPLYRVVPGQSEQVESFVLQLIAEQERVWELILTNDGYSWHCALYDILFHLVLRNM
                     EDQPEHQRQRITKILNESDTRRVAEEIKFRIQYLQDEEQKRVLSELVNVLISKR"
     gene            complement(7134..7403)
                     /locus_tag="IRB70_003116"
     CDS             complement(7134..7403)
                     /locus_tag="IRB70_003116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PerC family transcriptional regulator"
                     /protein_id="HBC0632999.1"
                     /translation="MVAQKLEAAGCWRRASARWLFVMGNVECTEAQREWLLLRRNYCL
                     AQISSPPLPEKLDISEVAKAADATLRRMGIASPSGEVFRKGTPVC"
     gene            complement(7482..8120)
                     /locus_tag="IRB70_003117"
     CDS             complement(7482..8120)
                     /locus_tag="IRB70_003117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB N-terminal domain-containing protein"
                     /protein_id="HBC0633000.1"
                     /translation="MGDSVTPEILSNMIRQYFSQERPEEEAIQALNHLRRVLHEVSPF
                     AQEPVDCVLWVKADEVVANDYNPNVMAPGEKKLLKHSLEQDGFTQPVVVSEEKEHYLV
                     VDGFHRQLLGREAGTGKRLKGWLPVTCINPERKGQASRIAATIRHNRARGKHQITSMS
                     DIVRDLSRLGWTDERIGTELGMDQDEVLRLKQISGLTELFLEEDFSPAWTVR"
     gene            complement(8105..9337)
                     /locus_tag="IRB70_003118"
     CDS             complement(8105..9337)
                     /locus_tag="IRB70_003118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoadenosine phosphosulfate reductase"
                     /protein_id="HBC0633001.1"
                     /translation="MNDNFLTEKVLTGENVLRAAIARIEWIFETFPSVCLSFSGGKDS
                     TVLFHLVADVARRKRRRFSVLFIDWEAQYQCTIEHIQKMREMYHDVTETFYWVALPLT
                     TVNGVSQFQPEWICWEPRVTWVRQPPEEAITDMAYFPFYRYAMTFEEFVPAFSSWFAG
                     NRCGVAVLTGVRADESLNRFMGLVSQRKLRYADDKPWTTASPEGFYYTMYPLYDWKTR
                     DIWIYHTRTRAIYNPLYDLMYRAGVPLRNMRVCEPFGPEQRKGLWLYHVLEPETWARM
                     CERVSGAASGALYANESGAYFALRKRISKPAHHTWRSYAMFLLDVMPERTAEHYRNKI
                     AVYLRWYQTRGFPDDIPDEQENDLGSRDIPSWRRICKTLIKNDFWCRTLSFSPNKPRH
                     YERYLQRMKERRKEWGIL"
     gene            complement(9478..10122)
                     /locus_tag="IRB70_003119"
     CDS             complement(9478..10122)
                     /locus_tag="IRB70_003119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001513967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633002.1"
                     /translation="MNGKYNVRSELLARCIGTGRLKGDVRSDFIGFNGSKQVGYVLLT
                     LFLTKVTNSDLLSHYRIFNRFLHYERKVMDIYNSLSDIEVDCICQEVMAIYEHTQRCC
                     NEKKITTIQLGRKLNGRYADTIAELKETAEIRGEDVISFEMDILNSFNDADEYHGRVK
                     LELDIPASDILYCHDFIDSKHVNSWLVEPHEWVVINRSLNGIVTVPVSSIKILY"
     gene            complement(10239..11105)
                     /locus_tag="IRB70_003120"
     CDS             complement(10239..11105)
                     /locus_tag="IRB70_003120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImpA domain protein"
                     /protein_id="HBC0633003.1"
                     /translation="MALPEAMVKGYITRLENQPVQGEVSSPVTLLAQALRLEAPDVQE
                     HQTLPHSRLVYVVSETKTEPTLFLQKSPLTFLKTFVTGVCTALLAVCVAIPGWQFLTQ
                     PSPAEQQLRALLTPSPDVLSADQMMQLSRTLLNHASEWITLSGQQITRLTEFPPAYNL
                     QRSVQLLQQLMVLFPDNPRVQEMVDNWQKSARSRALPEEAMTGWNEGMTRLQLLAERL
                     NRPDEQRGKYMTVSELKTEVSGIMQAFNRHILAEEQLCHYGEVRNQNGSEQQQKQMKD
                     AFVKLIHFYCFI"
     gene            complement(11146..11586)
                     /locus_tag="IRB70_003121"
     CDS             complement(11146..11586)
                     /locus_tag="IRB70_003121"
                     /inference="COORDINATES: protein motif:HMM:NF018516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ImpA family N-terminal
                     domain-containing protein"
                     /protein_id="HBC0633004.1"
                     /translation="MTSEVKLKTGGDPRSLPDYAALRDEISKLTHPARPDVDWRYVET
                     LCLRLYEHNGVELQTASWYTIARMHTTGLSGLNEGLALIAALTRHHWSVMWPLNTHSR
                     LEIITGLFNRLQKTLRAMPPDNRDNLPLLYQTETFLKTLSDLLP"
     gene            complement(11980..13725)
                     /locus_tag="IRB70_003122"
     CDS             complement(11980..13725)
                     /locus_tag="IRB70_003122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001529578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NERD domain-containing protein/DEAD/DEAH box
                     helicase"
                     /protein_id="HBC0633005.1"
                     /translation="MTSGERRVASRLESFLNDDCFVWYDIPVGRKNRHPDFVIIDPDN
                     GLVFLEVKDWTVSTLRKANQEQVTLETDGLLKSEINPLVQARRYACDTVNALPADPCL
                     RQNDGQYKGRLNLAWAYGVVFTRITRQQLKALTGNDENAVEKIFPSAQTICQDEMTQS
                     VLPEVFRQKIAGMFTTGFRTRVTPRMRDILRAHLFPEVTVKQNSQIKIMDIQQEILAR
                     NIGDGHRVIHGVAGSGKTMILLFRCLYLAETTPGKILVLCYNITLASYLRECIDVRGL
                     TSRVTVSHFHSWCASMIKRHGIQVTADRKDYPEKCFSTLEEAVNSGKITDAGYDAVLV
                     DEGHDFDSRWLALIARLFDNASRSLLLMYDDAQSIYRRERALNFSLASVGIQAQGRTS
                     VLPVNYRNPKRILHFAYAFSREYFEKHQNREIPLVQPQAGGEEGTEPEILHCASERDE
                     ARQVADWLEKCHALCGHWSVMAVLCPTEHSAKQLQDVMTQRGMPFATCFDREGKKAYS
                     RRKDVVHLLTYQSSKGLEFPYVAVINASFIPSGVADESEVIPVLYVAFTRATRELLVT
                     CYRENSISRHLEDFA"
     gene            complement(13868..14128)
                     /locus_tag="IRB70_003123"
                     /pseudo
     CDS             complement(13868..14128)
                     /locus_tag="IRB70_003123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611553.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            14849..15040
                     /locus_tag="IRB70_003124"
     CDS             14849..15040
                     /locus_tag="IRB70_003124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HBC0633006.1"
                     /translation="MSEDVPLPKVNQRYKDDHGALATVTSVEETRVVFMREGYPHPCM
                     RPMYNFLGKFKPDPREETE"
     gene            complement(15093..15326)
                     /locus_tag="IRB70_003125"
     CDS             complement(15093..15326)
                     /locus_tag="IRB70_003125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633007.1"
                     /translation="MARSDYDIINLSLEHELNEWLAERGYAGLAYNRNRVVEVVTRKL
                     QDSFYINVSWDALNTAYNEHPEWFSGLVSGDEN"
     gene            complement(15422..15921)
                     /locus_tag="IRB70_003126"
                     /pseudo
     CDS             complement(15422..15921)
                     /locus_tag="IRB70_003126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309404.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            16272..17390
                     /locus_tag="IRB70_003127"
     CDS             16272..17390
                     /locus_tag="IRB70_003127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001703486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase"
                     /protein_id="HBC0633008.1"
                     /translation="MARYYFSCPKIYFGEEAITSLCQFNNKRVGIVTDDFMMSSGKTR
                     YLISHMPEASVCIFGEVTPDPDIDILTSGAARFKAFKPDVIIALGGGSSLDAAKGIKV
                     TLEEYFGDHQIDLIAIPTTSGSGSEVTSYAIISDPQNGRKYPLISGQLVPEIAILDPN
                     LVLTAPRHVAVDTGMDVLTHAIEAFVSTGSNDFSDALAEKAIALTWRYLPQVFNDEKD
                     IAARTHMHNASCMAGMAFNSAGLGLVHGMAHAIGGMLHIPHGKINAMLLPIVIDFNSK
                     RASTETRDRYHRCAQIIGIDHAVPEQAIALMTQEIRQINRHFCIPVTLSELGIDRAKI
                     IELRSALVNSTLADGCTASNPRQVTTHDVEGLIDLITG"
     gene            17530..18216
                     /locus_tag="IRB70_003128"
     CDS             17530..18216
                     /locus_tag="IRB70_003128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001109983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate propanoyltransferase"
                     /protein_id="HBC0633009.1"
                     /translation="MNYTEQQAEWITQQILQELATSEKTAAPAAAPVALNIPVGVSNR
                     HVHLCREDMDILFGYGSTLTRSKALKQPGQYAAEEMVTLRGPKGELNKVRVLGPLRNA
                     TQVEISVADGFALGTKAPVRMSGDLLDSPGIEIIGPKGRVVKHNGMIVAWRHIHISPE
                     EAELHGLHDGMEIDVQTNGPRGGVLSHVVVRVTADAVLELHIDMEEANGVGLRNGDTV
                     RGIKQAARHG"
     gene            18271..19029
                     /gene="eutJ"
                     /locus_tag="IRB70_003129"
     CDS             18271..19029
                     /gene="eutJ"
                     /locus_tag="IRB70_003129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001332070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ethanolamine utilization protein EutJ"
                     /protein_id="HBC0633010.1"
                     /translation="MSALLRRVEGGGDLGTANIAIVVLDEDNQPVAGVMYPSNVVKDG
                     VVVDYLTASRVVARLKQILEQKQGCTLERAAIAVPPGISEGNTKVIVNVVELAGFIVT
                     QVLDEPVAAASALNIKNGAVVDVGGGTTGMSILKSGKVTFSADEPTGGSHMKLVIAGA
                     LGLPYAEAEEMKKNGQEAQVFTLVLPVAQKMASLVSGWFATQQVKNIYLVGGASSFSQ
                     FANVFSKQTGKNVIPSAEPLLVTPLGIAMNADQG"
     gene            19034..19738
                     /locus_tag="IRB70_003130"
     CDS             19034..19738
                     /locus_tag="IRB70_003130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633011.1"
                     /translation="MDNQTLSQLLDRVIAEVLAQSVAQKNVCVVVTGEDISSLPETLN
                     CLEALELAGYQLWVNFSHSASQSALKSVCMDALIQRGSRAGFDRSPPHYEVLYLPALS
                     VNSMSKIALGIRDNLACETVFQALQHRKQIIATLHQQCVDSELPMPLLSCLEGYAQVL
                     ESYGITLFGKRAAHVKSVQGSQSTLTVAGKKRLITQSDIRLLTIGTVLRIESDTLITP
                     AARDEIQRRNLTVIHG"
     gene            19750..20019
                     /locus_tag="IRB70_003131"
     CDS             19750..20019
                     /locus_tag="IRB70_003131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EutN/CcmL family microcompartment protein"
                     /protein_id="HBC0633012.1"
                     /translation="MYLAKVTGALVSTTKHASLNGSKLLIVARLDENYQPTVHAQVAV
                     DTVGAGNGEIVIITTGSSARMSNNKDHSVIDAAVVGIVDSLELNG"
     gene            20047..20544
                     /locus_tag="IRB70_003132"
     CDS             20047..20544
                     /locus_tag="IRB70_003132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme-binding protein"
                     /protein_id="HBC0633013.1"
                     /translation="MSANEASLDNWINEAIATQLPELRMSLSLEDSELLAKLVREMAQ
                     SSNVSIVFSLVDACGQQRFFFSMDNALLVSHTLAPQKAWTAVALKMPTHELATLVQPG
                     GDLYGLEKEKDICCFGGGFPCWSGRRLLGGIGISGGSVEEDMLIARQAMAQFSVLRYP
                     LTTTR"
     gene            20573..21769
                     /gene="tdcD"
                     /locus_tag="IRB70_003133"
     CDS             20573..21769
                     /gene="tdcD"
                     /locus_tag="IRB70_003133"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HBC0633014.1"
                     /translation="MSLACVLVINCGSSSMKFSVIPQDADQPLLSGLAERLGIDHAVI
                     TFKDRDGHKSTVALDDASHQHALKVLFAKLDEQQLLEAINAVGHRVAHGGSDFKRSVL
                     VTDDVIEKVRALSVLAPLHNPANLIGIEAARALLPALPHIAVFDTAFHQTLSPAAYTY
                     AIPLEFQQDYMVRRYGFHGTSHRYIAAEALASLDLDPADHGIVIAHLGNGSSLCAVQN
                     GTSIDTSMGMTPLEGLVMGTRCGDLDFGVVAYLAKRTGQTFDTLYKMLNNQSGLMGIS
                     GLSSDCRTLQQARDEGHERAALAIDVLVHRLARHIGGHVTSLKRFDALIFTGGIGENS
                     ALIRELTVQRLQALGLELDKERNQQLFGGRSGLISKTDTTKIAVIPTNEEKMIAIDAA
                     EIARTA"
     gene            22054..22335
                     /gene="pduA"
                     /locus_tag="IRB70_003134"
     CDS             22054..22335
                     /gene="pduA"
                     /locus_tag="IRB70_003134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001301171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduA"
                     /protein_id="HBC0633015.1"
                     /translation="MQQEALGMVETKGLVSAIEAADTMVKSANVTLVGYEKIGSGLVT
                     VMVRGDVGAVKAATDAGSAAASKVGELVSVHVIPRPHIEVEKILPKAIG"
     gene            22357..23142
                     /gene="pduB"
                     /locus_tag="IRB70_003135"
     CDS             22357..23142
                     /gene="pduB"
                     /locus_tag="IRB70_003135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001205499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propanediol utilization microcompartment protein
                     PduB"
                     /protein_id="HBC0633016.1"
                     /translation="MRDNLVEQIISDVMNKQTDISPEAKTAANFAGCGITEFVGTALG
                     HTIGLVIANVDNQLHEVMNIDKKYRSIGILGARTGAGPQIFAADEAIKATNSEIISIE
                     LARDTEGGGGHGCLIIFGASDVSDVRRAVEVALSEIERTMGDVYGSSAGHLEFQYTAR
                     ASYALNKALGAPIGKSFGMTCASPAAIGLVIADAAAKSAVIDPVGYASPSQGTSFSNE
                     VIFTFSGDSGAVRQAVIAAREVGLQLLSTLDPVEIKSTTTPYI"
     gene            23203..24720
                     /locus_tag="IRB70_003136"
     CDS             23203..24720
                     /locus_tag="IRB70_003136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase EutE"
                     /protein_id="HBC0633017.1"
                     /translation="MNDIEIAQAVSTILSKFTKTTPDEAPATSEAARVEGLDEIVAKA
                     LAQHSSVRDASAISQVAKVANASTGAFDTMDEAISAAVLAQVQYRHCSMQDRASFING
                     IRDVFLQEDVLCALSRMAVEETGMGNYEDKLIKNRVAALKTPGIEDLTTSAVSGDGGL
                     TLIEYSAFGVIGSITPTTNPTETIINNSIGMLAAGNTVVFSPHPRSRKVSLYAVELIN
                     NKLAQLGAPANMVVTVTKPSIDNTNVLINDPRINMLVATGGPAIVKTVMSSGKKAIGA
                     GAGNPPAVVDETADIEKAARDIIKGCSFDNNLPCVAEKEVIVVNQVADYLIHCMKKSG
                     AYLLCDKKLSQQLQSLVLNEKGTGPNTAFVGKDARYILQQLGIQVGDDIKVILIEAEK
                     THPFVVHELMMPVLPVVRVDNVDEAIELAVKVEHGNRHTAVMHSTNVEKLTKMARLIQ
                     TTIFVKNGPSYAGLGVGGEGHATFTIAGPTGEGLTSARSFARRRRCVMVEALNIR"
     gene            24744..25043
                     /locus_tag="IRB70_003137"
     CDS             24744..25043
                     /locus_tag="IRB70_003137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000746009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBC0633018.1"
                     /translation="MKKRIINAPTPDILAMLKRRMPGEFRSRLDLIRIDAIGLLILPV
                     PDLYFYADVASKSANVVVSEIFGSCPQHITTLAIFGEVAAVHEAMRIIEEDDNQF"
     gene            25054..25629
                     /locus_tag="IRB70_003138"
     CDS             25054..25629
                     /locus_tag="IRB70_003138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DJ-1/PfpI family protein"
                     /protein_id="HBC0633019.1"
                     /translation="MKKILLITGDFSEDYEVMVPWQALNMLGFRVDVVCPGKRTGEFI
                     KTAIHDFEGDQTYTEKPGHLFRLTASFDDIRLQEYSGVYISGGRSSEYLRLNKSVLDI
                     VHYAMNLTLPVAAICHGPQILAAAGVLKGRKLTGYFTVKPEVEMAGGQWVTAADDEAI
                     VDGNLITATTWMGHPAILRHFITQMGTSIIH"
     gene            25678..28230
                     /locus_tag="IRB70_003139"
     CDS             25678..28230
                     /locus_tag="IRB70_003139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000890296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl radical protein"
                     /protein_id="HBC0633020.1"
                     /translation="MLEKGFSNPTDRVVRLRNMILTAKPYVESERAVLATEAYKETEQ
                     LPAIMRRAKVVEKIFNQLPVTIRPDELIVGAVTINPRSTEICPEFSYDWVEKEFETME
                     HRIADPFVIPKKTAQELHEAFKYWPGKTTSALAASYMSEGTKESMASGVFTVGNYFFG
                     GVGHVSVDYGKVLKIGFRGIINEVSRALESLDRTEPGYIKKEQFYNAVLISYNAAIRF
                     AHRYAEEASRLAQQESNPTRKRELEQIAQNCTRVPEYGATTFWEACQTFWFIQSMLQI
                     ESSGHSISPGRFDQYMYPYLESDKSISREFAQELVDCCWIKLNDINKTRDEVSAQAFA
                     GYAVFQNLCCGGQTEDGRDATNDLSYMCMEATAHVRLPQPSFSIRVWQGTPDEFLYRA
                     CELVRMGLGVPAMYNDEVIIPALQNRGISLRDARDYCIIGCVEPQAPHRTEGWHDAAF
                     FNVAKVLEITLNNGRVGNKQLGPVTGELTQFTSMEDFYTAFQKQMAHFVHQLVEACNS
                     VDIAHGERCPLPFLSALVDDCIGRGKSLQEGGAIYNFTGPQAFGVADTGDSVYAIQKQ
                     VFEDRKLSLSELKSALDANFGYPVGANPHTPAAKSSLNEQDIYDVVKRIIEHHGALDP
                     AAIKNEVYRQLTSGSAAPVQSGTMSRHEEIRRILENTPCFGNDIDDVDLVARKCALIY
                     CQEVEKYTNPRGGQFQAGIYPVSANVLFGKDVAALPDGRLAKEPLADGVSPRQGKDTL
                     GPTAAANSVAKLDHFIASNGTLYNQKFLPSSLAGENGLRNFSGLIRHYFDKKGMHVQF
                     NVIDRNTLIEAQKNPEQHQDLVVRVAGYSAQWVVLAKEVQDDIISRTEQQLS"
     gene            28339..29256
                     /locus_tag="IRB70_003140"
     CDS             28339..29256
                     /locus_tag="IRB70_003140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002438292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycyl-radical enzyme activating protein"
                     /protein_id="HBC0633021.1"
                     /translation="MNKVEYETEGVIFNIQRYSLHDGPGIRTIPFFKGCPLSCKWCSN
                     PESQRHSPELLFKKNDCIRCGKCIDACPQQALSTTNAWFINRDRCIQCGKCTEICPTR
                     ALEMKGKRMSVTAVMRELEKEENLYRRSGGGITLSGGEPLAQPEFARELLKACKAKGW
                     HTAIETSGFTTKAVIDEVFPYVDLALTDIKAIDPEIHERNTGVNNRVILENLLRISFL
                     TKVVVRIPVIPGVNDNSQEIHNIAEFARLMQNVDTIHLLPYHSFGENKYNLLGRQYPM
                     GDTKSIEEAQMAELKAMVESLGFNCHIGG"
     gene            29393..>29703
                     /locus_tag="IRB70_003141"
     CDS             29393..>29703
                     /locus_tag="IRB70_003141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBC0633022.1"
                     /translation="MNSLDIVVAFGGGIFGAAVGALAAFEFVGLLVIAMTVVQIITGA
                     SSDFITFPFGLFGPHTGGFAAGVAATAYAAKKGKLGSGRDITAGLSGLAAYDVLLVGG
                     V"
BASE COUNT         7691 a         7255 c         7271 g         7486 t
ORIGIN      
        1 ggagtgcttt agctggcata acgggctact gatctcctct ggttacagat aacgacttca
       61 gccctctgaa agagaaaagc ggaagctcag gaaggttgtg atttgctttt aaccttttta
      121 atttagaagt attattttga gattaatcca cttcccatcg tcatcctttt tggtgtgcgt
      181 gaaaagctat ttttaaggtt actgcctcat ggagttatgg atatttatag tagctattta
      241 tttgatttat attctttttt tcaaaaagaa gaaaactaag tccgcgggct cttatacttc
      301 cgctcctgtg aaagcaccac ctaaagaatg gcttgctaac aacaaaaaaa atcagtctgt
      361 aatgcaaaac gaggacagcg aagatgacaa tctggctacg tttacactaa gtggcgggcg
      421 gaatgtcgaa tacagcataa cagccactca acgccagaat ttctcaaaaa ctaccggtgc
      481 tttggctcgt tggatttttc cgggagagat gatcacaatc agtgggatag aggttaccgg
      541 cggtcacttc tatcttgggc agcgtatgaa acctgccggg cataactcag gcggttatta
      601 tgatggcaat aacgaggcat cgctagttga cgacacgctt aaaatatacc ccacacctta
      661 catttacgaa gatagttcat tagggtattg gcccagtttt tcctcacttt cacctgaagc
      721 tcgtggtgcg tacctgagtt ggcttgccag cgacagatgc gacacttcct gcccaattgg
      781 ttacgttttc atttatctgt atggtctgga aagaagggcg cttgttgaca gcagggacaa
      841 caatatatcc gacgatgagt tctattctct tttcaaagag atctgccgtc tcagatcggt
      901 tttcaatgaa aaccgatctt tccggaatta ctcatcccag ttacttgaag cgatgtccat
      961 tcttcgtccg aacgaaaatc ttgcagcagc tctcaacgat gattcggagt tcagcaatag
     1021 catgcagttc aggttaatcc tggcaaagac tgttgataca ggagccccgg ttccagcgga
     1081 tctggctctg acgtgggtga caaaccatgc tgaatactca ttacgaaccc ccgcccgccg
     1141 ctgtgcgaaa gaatttgctg cactatttaa acggcgttac acccttaaat acggtgaagg
     1201 gatggtagtg aagccgaata aagcgcgtct gcgtttagat tacacgcctg caagtcccag
     1261 tttgcgaggt attcggcttc ctgttcccga cttgcctgat ccaggtgcat tgaaaggccc
     1321 tgttcagaag cttatggcca ttgccgatat atgcacaggt gaactggatg cttacagtcg
     1381 ttaccttggt agaaaaggta cttcagcaaa tgataccgct gcaattttgt tgctgccttc
     1441 agaaatcgtt aacgaaagcg cagaaaaaat attaagtaca ttcaaacact gggctgatga
     1501 cgcaatccgc agtaagggtg ggatagtttc agttgctgac tactggtcac atatgaatgc
     1561 cacctgtccg gcgaagatca ataaaaaaga ggccgactta atgcaagcct ttgcacagaa
     1621 aatgggatac tgtctggctc ctgaccccta tcaccaccac gtaaaggcag atgtcgatgg
     1681 tgtacttgtt ttattccctg ctggtgaaag aggacgtttc tcaccttctc ctgaatttat
     1741 cacagctgta ttgacgctcc gattaggttc ggtagtcgcc ttgattgaca attctctcga
     1801 tcaagccgaa cagaaagtgc ttgagaatgc catcaacaac aatgccagct tcagcgatga
     1861 tgaaaagcgc tctctgcacg catatttaac gtggcagctt catactccgg cgaatatgac
     1921 gggaatgaaa agccggattg aattactcgg tgcagcggaa aaatcagctg tgggtaaggt
     1981 tatcgttagt gtcgcttgct ctgacggcag aattacgcct gccgaaatca aacagcttga
     2041 gaagatttat acaagcctgg gactggatcc ctcatccgta tcaagcaata tccatcagca
     2101 ttccgcaact gaaactgctc tcgtttcatc tgtaccagct aatcagtcga cggcaggatt
     2161 tacgctggat gccaacgtac ttgcccgcca cgaatctgcc actgatgatg ttcgtaaatt
     2221 actgaactca attttcactg aagaagaacc agaacaacca gaaagcgctc cagcctcatt
     2281 aaccggggaa gggggacttg actccgctca tagccaactt tatcgcaggt tgctggagaa
     2341 agaacaatgg tccagaaaag aggcgacaga gttgtgtagt aactggaacc tgatgctcgg
     2401 cggtgcgctt gaggtgatta acgattggtc ctatgcggtg gttgatgcac cagtgctgga
     2461 agatgctgat gatcacattt ggattgacct ggaaatagcc aaagaattag agggttagtg
     2521 aatgtctgta acacgtataa gagtgaaaga gcgcgacgct atcattcagt cacttaagtc
     2581 gggagtaacg ccaagaatag gtattcagca tatccaggtt ggccgcgtga atgagataac
     2641 cgccctccat caggatattg aacggattgc tgatggcggg gcaagcttca gacttatcat
     2701 tggtgagtac ggttccggga aaacattctt tttaagtgtt gtacggtcta ttgcgttaga
     2761 gaagaagctg gtcacggtca gtgcagacct ttctcccgac agacgtatcc actcatcggg
     2821 aggtcaggct cgtaatctct actcagagct tatgaaaaat atgtccacca gaaacaaacc
     2881 agatggcaat gcattactta gcgttgtgga aaggtttgtt actgaggcaa ggaaggaagc
     2941 tgatgcgaac ggctccctgg tctcatccgt tattcataaa cgccttgctg ctttgtcaga
     3001 tatggtggga ggatatgact ttgcgaaggt cattgacgca ttctggcgcg ggcatgagca
     3061 ggataacgaa accttaaaat ccaatgctat tcgctggttg cggggcgagt acaccacaaa
     3121 aactgatgcc cgtaatgatc ttgacgtccg aacgattatc tcagacgcct cgttctatga
     3181 ttctttgaag ttgatgagcc tttttgtccg tcaggcaggc tatgccggac ttttagttag
     3241 cctcgacgag atggtgaacc tcttcaagtt gaataatacg caagcgagaa cggccaacta
     3301 cgaacaaatt ttgcggatcc tgaatgactg cctgcaaggc tccgctgaaa atattggttt
     3361 tatcctcggg gggacgccag aatttctttt cgatccacgt aaggggctct acagctatga
     3421 agcgctccag tcgcgtctgg cagaaaaccg attcgcacag aaagctggcg tgattgacta
     3481 ctcgtccccc acgctgcatc ttgccagcct cactcctgag gaactgtata ttttactgaa
     3541 aaaccttcgt catgtttatg ctggtggaga tcccgcaaat tatctggtgc cagatgatgc
     3601 tctgaccggg tttctgcatc actgcagcaa aaccatcgga gatgcttact ttcgaactcc
     3661 ccgcaatacc ataaaaggtt ttctggatat gctggctgtg ctggaacaaa acagaacgat
     3721 gaactggcaa accctcattg agggggtggc gattgaagaa gacaagctca gcgatatgga
     3781 tgatgccatt gtggaggaaa gtgatgacga tgatggcctg gcgaatttca gattatgagt
     3841 agtgcctaca atagtcttga tccccgtgtc cgtaagtggg tttataagca gggctggtca
     3901 tccttaaggc ccttgcagga aagctctatt ccggcaattt tagcccgtga tcgtgatgta
     3961 ctaattagtg caggtacagc tgcgggtaaa acagaggctt tctttcttcc tgcctgttca
     4021 gcgattgcag atctcactgg tggatttggc attatctata tcagtccatt gaaggcatta
     4081 attaacgatc aacaccgtcg tcttgagagt cttggtgaag ccctggaaat gcaagtgacg
     4141 ccctggcacg gggatgtacc acaaagcaaa aagaagaaag cacggacaac cccttctggc
     4201 atcttactta tcacacctga atcacttgag tctttgctca taaactcatt gggttggctc
     4261 aaacaggcgt tttcttctgt ggcatacatt gttattgatg agttccatgc ttttattggc
     4321 tcagagcgtg gtatacagct gctttctctg cttaacagaa ttgaccatgt gctgggacgc
     4381 cagttgaatc cagttccccg tgtcgcgttg agtgccacgc tgggagagct ggaaaaagta
     4441 ccagaactat tgcgcccgga taagagatta ccttgtgaaa cggtaacaga cagtaatagc
     4501 aaagccacac tacaggttca ggttaaaggt tatcttgagc gggtgcccga aaaaggagaa
     4561 gagctccaga gctctgctga acagctcgtc tgcgcggata ttttcaggct ctgccgtggc
     4621 gattcccacc tggtctttgc taacagtcga aagcgtactg aaagcatagc ggcaacactg
     4681 agcgacatgt gtgaagcaaa tgtcgttcct aatgaattct ttcctcatca tggttccctt
     4741 gcaagggagt tgcgtgaggc gcttgaagcc cgactgcaga aagggaattt gcccacaacc
     4801 gctgtttgta caatgacgct ggagctgggt attgatattg gtaaggtgca gtctgtcata
     4861 caagtgacac ctccgcattc tgtttccagt ctgcgtcaac gcatgggacg ttcagggcgg
     4921 cgcgattccc catcggtgct gagaatgtta attactgaac ctgaacttac cgcaaccagc
     4981 agcattgtgg atcatttacg gctgcagttg gttcaggcga tggcaatgat caggttgatg
     5041 atctctaagc gctggttcga gcctgcagat atccggcaga aacattactc cacactacta
     5101 caccagatcc tggctattac tgcgcaatgg ggaggtgttc gtgccgatca gctctggtca
     5161 caactttgcc agacaggtcc gttccggaat gtggatataa atgacttcaa aagtctgctt
     5221 aaacatatgg ggacatgtgg cctgctcact caactaacca gcggtgaaat agttgtcggg
     5281 gctgaggggg agaagctgac taatcactac acgttttatg ccgtattcaa tacacctgag
     5341 gagtttcgca ttgtaacggg aaaccgaact cttggcacag tgcctgtaga ctccccactt
     5401 ttgccggagc agcacatcat cttcggcgga cggcgctgga aagtgacaga gatcgaggtt
     5461 gaaaaaaagg ttatctatgt tgagacgact aaaggcggtc agccgccact attcagtggt
     5521 accgggatgt ctgttcatga tgttgttcgc caggaaatgc tcactatcta cagggaaaat
     5581 gattaccgta tcgcggtagg caacaagaga gtcgattatg ctgatgccgc agccagaagc
     5641 ctcttcgcgg aaggaagtga caacttccaa cgctacaatc tacaaaatga ctgttttatt
     5701 gccagtggtc agaactgcta cgtgatcccg tggatggggg ataaaattgt caatacaatt
     5761 acgtccctga ttatacgttg tggctttaaa gccagttcat ttgcaggtgt gatagaggta
     5821 gaggactcag gcgttgcctc tgtccagcgt gcacttaaga aaatgctatt gtcggggcta
     5881 ccttcagagt ttgagcttgc tgcagttgtt cccgacaagt atctggataa atatgacgag
     5941 tatttaccag agactttgct tgctaaaggg tatggggcac aggcgtatga tatagaagga
     6001 acgtgcatct ggctgcagaa acaccttcag tagactggat atgtagtcag ggtataaata
     6061 agtatttata cccttatttt ttacttacct gtggacttac ttggctttaa tcccggagta
     6121 ttgccaggag tatctttatt atcgcgtcgg cgttgatccg gttttcctgt tgacttagca
     6181 attggttttg gacctggttt tagacccatg atagttatcc ttcgagatgt aagaggaatg
     6241 ccctcaacat tggtatattc tatactgaga aatttttcaa tgggaatgtt caacggccga
     6301 atgattaact cgatattgtg agcaatgtct ttttttggca cagagcgaac cgttagattg
     6361 cgcgtatttt tatggaagga gatcatccaa taacggttat tcaccgatct cctttatggt
     6421 aatacgaacc tgttttttta atatatagaa aaattactcc gacatgtttt atctttttga
     6481 aatcaggaca tttaccaact cacttaaaac tctcttttgt tcttcatcct gaagatattg
     6541 aatccggaat ttaatctctt ctgcaacccg ccttgtatcg gactcattaa gtatttttgt
     6601 tattcgctgt ctctgatgtt caggctggtc ttccatattt cgtaaaacca gatgaaataa
     6661 tatatcataa agtgcgcaat gccatgaata accatcattg gttagaataa gctcccaaac
     6721 ccgctcctgt tcggcaataa gctgcagaac aaaggattca acctgttctg attgtccggg
     6781 gacaacccgg tatagcggcg caatcacagc aaaaaacagt tcatttagcc aggattccgc
     6841 ctctttctcg ctcctgaaag atggacagtt ctgtattctt cgttcgtatt cacgggtaac
     6901 ctgctccgga atatcctccg gcggtgtcag ccacttattc ctgagcaata tactggttga
     6961 cggatggcag caggctattt cagcaataat ttcacgtaat gcctccgggc tgaatttctt
     7021 cagctgattg tagtgctccc gggtaaaacc atgatcatcg cataaaagtt gccatgtcat
     7081 tgatatactg tttgccattc ctttcttcat cattaatacc tgttacctga atatcaacag
     7141 accggtgtac cttttctgaa tacctccccg gacggactgg caatccccat tcgcctcagc
     7201 gtggcatctg cagctttcgc cacttcgctg atatccagct tttcaggtag cggcggggac
     7261 gatatctgcg ccagacaata attcctgcgc aacaacaacc actcccgttg tgcttctgta
     7321 cattcaacat ttcccataac aaaaagccag cgggcggaag ctctgcgcca gcaacccgca
     7381 gcctccagct tctgtgcaac catgtcttcc acgacttccg gggtactctt tttcctgctc
     7441 aaaacattaa ctcactgaaa taatatacat atatgacggt ctcagcgaac cgtccatgcc
     7501 ggactgaaat cctcttccag aaacagctcc gtcagcccgc taatctgttt caacctgaga
     7561 acttcatcct ggtccatacc cagctccgta ccaatacgtt catccgtcca gcccagccgc
     7621 gacaggtccc tgacaatatc agacattgaa gttatctggt gcttccccct ggcccggtta
     7681 tgtctaatgg ttgcagcaat acgtgaggcc tgtccctttc tttccggatt aatacaggtc
     7741 actggcaacc agcccttcag gcgttttccc gtacctgctt ccctgcccag taattgacga
     7801 tgaaaaccat ccacgaccag ataatgctcc ttctcttccg agacaaccac aggctgcgtg
     7861 aacccatcct gctccagtga atgtttcagc agtttcttct cacccggcgc catgacattg
     7921 gggttataat cgttggccac cacctcatct gctttcaccc acagcacaca gtccacaggc
     7981 tcctgtgcaa atggactgac ctcatgaagc accctgcgca gatgattcag ggcctgtatg
     8041 gcctcttctt ctggtcgttc ctggctgaag tactgacgaa tcatgttgct cagtatctcc
     8101 ggtgtcacag aatcccccat tccttcctcc tttctttcat acgctgcaga taacgttcat
     8161 agtgccgggg tttgttcgga ctgaaggaga gggtacggca ccagaaatca ttctttataa
     8221 gtgtcttaca gatacgccgc caggacggaa tatcccggct ccccaggtca ttctcctgtt
     8281 catccgggat gtcatccggg aagccccgcg tctgatacca gcgcaggtag acagcaattt
     8341 tattacggta atgttctgcc gttctttccg gcatcacatc cagcaggaac atcgcatagc
     8401 tgcgccaggt atgatgggct ggttttgata tacgtttacg cagggcaaaa taggcaccgc
     8461 tttcattggc ataaagcgcc ccgctggcag cgcctgacac ccgctcacac atcctggccc
     8521 aggtttccgg ttccagaaca tggtaaagcc acagtccctt acgttgttca ggaccaaaag
     8581 gttcacagac acgcatgttg cgtaacggta cgccggcacg gtacatcaga tcatacaggg
     8641 gattgtagat ggcacgggtt ctggtgtgat atatccagat atcacgagtt ttccagtcat
     8701 acagcggata catagtgtag taaaaccctt caggcgatgc cgtggtccaa ggcttatcat
     8761 cggcatatct cagtttgcgc tgggacacca gtcccataaa gcggttgagg gattcatccg
     8821 cccgaacacc ggtcagcact gccactccac accggttgcc agcaaaccag gaagaaaatg
     8881 ccggaacaaa ttcttcaaac gtcatggcat accggtaaaa gggaaaatac gccatatccg
     8941 taatggcctc ttccggtggc tggcgaaccc aggtcacacg aggctcccag catatccact
     9001 ccggttgaaa ctgcgagaca ccgtttaccg tggtcagggg aagcgccacc cagtaaaagg
     9061 tttccgtcac atcatggtac atttcccgca tcttctgaat atgttcaatg gtgcactggt
     9121 actgagcctc ccagtcaatg aacagtacag agaaacgacg tcttttcctg cgggccacat
     9181 cagccacaag atggaaaagc acggtggaat ctttaccacc ggaaaaagag agacaaactg
     9241 atggaaatgt ttcaaaaatc cactcaatac gagcaattgc tgcacgcaga acattctctc
     9301 cagtaaggac tttctccgtt aaaaaattat cattcattta tttttacttt atgcaaaaga
     9361 aacctgttta tgctttcaac atatagcaac aaacattaaa tgacgtttaa ttagccacta
     9421 ctaaaattgc ttactttcat cctgatgaac atataaaaca tattacaaac atatttatca
     9481 ataaagaatc tttattgatg atactggcac tgtaacaatc ccattgagag aacgatttat
     9541 aaccacccac tcatgtggtt caaccaacca ggagtttaca tgttttgaat caataaaatc
     9601 atggcaatat aatatatctg aagcaggtat atccaactcc agtttaacac gtccgtgata
     9661 ttcatccgca tcattaaaag aattcaatat atccatctca aaagaaatca catcctcccc
     9721 tcttatctct gctgtttctt ttaactcagc aatcgtatct gcatacctgc cattaagttt
     9781 cctgcctaac tggatagttg tgattttctt ttcgttgcag catcgctgag tatgttcata
     9841 tatagccatc acttcctggc aaatacaatc aacttctata tcactcaaag aattatatat
     9901 gtccataact tttctctcat aatgcaaaaa acgattaaat atacgataat gagagagcaa
     9961 atcagaattt gttactttcg ttaagaataa agttaataaa acataaccta cctgtttact
    10021 accattaaac ccaataaaat cacttctcac atctcctttc aatctaccag ttccgataca
    10081 acgagctaac aattcactcc tgacattata tttaccattc atattcacca tactattcga
    10141 aacaacagac gaacatccaa aagcgcttaa acactccaca aacaaactat ctcaccgaat
    10201 aaattgcaac actcccctta ccccacatcc taaaggcttt atataaaaca gtaaaagtga
    10261 atcagcttaa caaatgcatc tttcatttgt ttttgctgct gctcgcttcc attctggttg
    10321 cggacttcac catagtgaca caactgttct tctgccagga tatgccggtt aaaagcctgc
    10381 atgatgccag acacctccgt tttcagctca ctgaccgtca tgtattttcc ccgctgttca
    10441 tccggacggt tcaggcgctc agccaacagc tgtaagcggg tcatgccttc gttccagcca
    10501 gtcatcgcct cttccgggag cgcacgactc cttgcactct tctgccagtt atccaccatt
    10561 tcctgaacgc gaggattgtc ggggaaaagt accatcagtt gctgcagcaa ttgcacactg
    10621 cgttgcaggt tgtatgccgg ggggaattct gtcagtcgcg ttatctgctg accggaaagg
    10681 gttatccact ctgacgcatg atttaacagt gttctgctga gctgcatcat ctggtctgct
    10741 gaaagcacat ccggtgaggg tgtcagcagc gccctgagtt gctgctccgc cggtgatggc
    10801 tgtgtcagaa actgccatcc cggaatggcc acgcagaccg ccagcaatgc cgtacagaca
    10861 cctgtaacaa acgttttcag aaacgtgagc ggggattttt gaaggaagag tgtgggctct
    10921 gtttttgttt cagaaacaac atacaccaga cgggagtgcg gcagggtctg atgttcctgc
    10981 acatccggag cttcaagcct gagtgcctgc gccagtagcg ttaccggaga cgatacttcc
    11041 ccctgcacag gctggttctc caggcgggtg atatatccct tcaccatggc ttccggtaaa
    11101 gccactttac tgctctgttt aagttcgtgc caagcctgcg tattttcatg gaaggagatc
    11161 actcagtgtc ttcaggaatg tttcggtctg atacagcagg ggcaggttgt cacggttatc
    11221 cggaggcatg gcccggagcg ttttttgcag acggttgaac agaccggtaa taatttccag
    11281 ccgggagtgt gtattcagcg gccacatcac tgaccagtga tgccgggtca gcgcagcaat
    11341 cagagccagc ccttcattca gaccacttaa ccctgttgta tgcatccggg caatggtgta
    11401 ccaggatgcc gtctgtaatt ccacgccatt gtgttcatac agacgcaggc agagcgtttc
    11461 cacgtaacgc cagtccacat cagggcgtgc cgggtgggtc agtttgctga tttcatcgcg
    11521 cagggcagca taatccggta atgaccgggg gtcaccaccg gttttcagtt tcacttcaga
    11581 agtcatcggc agattcagtg tttaggtatt aaaccattgt taattatagg gagagagtca
    11641 gtgcgatacc gttacccagg aaaggtattc cactgcgcag atgattgccg gtgtcacatc
    11701 ccaccgccgt ttcagaaccg gtaacagctc attaaggttt ctgatataac gctcagtgaa
    11761 aaccggactg attacaggta atggtgatat gacaggtatc gttgccaata tacacggctt
    11821 ccagaggtat gaatcttaca ttccagtacc aggagtacgg cgagtggttc agatgaaaaa
    11881 gacgcatctg aatatcgtta aataacgggt tcatggcgaa ttaaataaac ctgataataa
    11941 cagtatgggg aaagtccgga ataaagaaat ggtccagtat tatgcaaaat cctcaaggtg
    12001 acgactgata ctgttttcac ggtaacaggt caccagtaat tcacgggttg cccgggtgaa
    12061 cgccacataa agcaccggga ttacttcaga ctcatccgct acaccagaag gaatgaaaga
    12121 cgcattgata accgccacat acgggaactc cagcccctta ctgctctgat atgtcagtaa
    12181 atgcaccaca tccttacgtc gcgagtatgc cttcttgcct tccctgtcaa aacaggtggc
    12241 aaaaggcatc ccgcgttgtg tcataacgtc ctgcaattgt ttcgctgaat gctctgtcgg
    12301 acacagcaca gccataacac tccagtgacc gcacagggca tggcacttct ccagccagtc
    12361 tgcaacctgt ctggcttcat cacgttcaga agcacaatgc aggatttccg gctctgtacc
    12421 ctcttcaccg cctgcctgtg gctgaacaag tggtatttca cggttctgat gtttttcaaa
    12481 atactcgcga gagaatgcat aagcaaagtg cagaatgcgt ttcggattac gataattgac
    12541 cggcaggaca gaagtgcgtc cctgcgcctg aatccccaca ctggccagag aaaagttcag
    12601 agcccgctcc cgccgataaa tggactgggc atcatcgtac atcaggagca gtgaacggga
    12661 tgcgttatca aacagacggg caatcagggc cagccagcga ctgtcaaaat catgcccttc
    12721 atccaccagt acagcatcat atccggcgtc ggtgattttc ccgctgttca cagcctcttc
    12781 cagtgtgctg aagcatttct ccgggtaatc ctttctgtca gccgtcacct gaataccgtg
    12841 gcgttttatc attgaggcac accagctgtg aaaatgagat accgtaaccc gtgacgtcag
    12901 ccctctgaca tcaatgcatt cccgcagata actggccaaa gtaatgttgt agcacagcac
    12961 cagaatcttt ccgggcgtgg tttcagccag gtaaaggcaa cggaataaaa gaatcatggt
    13021 ttttccggag ccggccacac catgaatgac acgatgcccg tcaccaatat ttctggccag
    13081 aatctcctgc tgaatatcca tgattttgat ttgtgagttc tgtttcacgg tcacttcagg
    13141 aaacagatgg gcgcgcagaa tatctctcat ccggggtgtc acccgggttc tgaatcccgt
    13201 ggtaaacatc ccggcaattt tttgccggaa tacctcaggt aaaacagact gcgtcatttc
    13261 atcctgacag attgtctgtg ctgaaggaaa aatcttttcc accgcattct catcattccc
    13321 tgtcagtgcc ttcagttgct gacgggtaat gcgggtgaac accacaccat acgcccaggc
    13381 caggttcagc cgccccttat actgaccgtc attctgccgt aagcacgggt cagcaggtaa
    13441 ggcattaacc gtatcacatg cataacgacg agcctgtacc agcggattta tttctgattt
    13501 cagaagaccg tcggtttcca gtgtaacctg ctcctgattt gctttacgta atgtggatac
    13561 agtccagtcc ttgacctcca gaaataccag cccgttatcc gggtcaataa tgacaaaatc
    13621 cggatgtcgg tttttccgtc ccaccgggat atcgtaccag acaaagcaat catcattcag
    13681 aaagctctcc agtcgtgaag ccaccctcct ctccccggac gtcattctct cctcagtgga
    13741 cgccgataca tttatcagtt tcgccataaa cgcaccttaa tctgcgaaca aaaaaagaat
    13801 catcaccgac acccacgacg ttatatcgtg gatgtcgctt tattcagaaa taaaaaaact
    13861 gaagtggtca acaaaaactg gccaccgcgt tagagttttt ccagtatcga ttttccgatt
    13921 cgtttggggg taacccacca ttatattcgt gcggtcttag tgcgctgtaa tatccaacga
    13981 tatagtccgt tatggcgtga gctgcctcgc tgaagcttac gtaacccacc accggcatcc
    14041 attcgttctt cagactcctg aagaagcgtt ccattgggct gttatctcag cagtttccgc
    14101 gccggctcat actctgcgtg atctggtatc cgcggcctga agagataaag gcgataataa
    14161 aacagacatc agtgtcagtg acagcaagga cggacagcgc cggaataagc tttgttcctc
    14221 agccctctcg ttcctgcaac ataattttcc agtcaaacga aaaacctttt attcatgtca
    14281 taccaacaat caccagcctc ctgacgatac ctcccaccat gttttgcgat ggcacgctac
    14341 cgcctttccg gtatttaccc acatcaaccg gtaccagaat gctgagtaat aaatctgcca
    14401 atttttagct gacttaattt tgatcattat agaataatga tctgaactac agcaatatgg
    14461 cagatttatc gatcgatata atacaaatga acagttcttt attctgacta atatcgcaaa
    14521 aacagcacat tacaaaattt ataaccataa ttaatggaaa agtgcagaaa attattccac
    14581 tgaatgcttt taatacagtt ggttagctta aaaaatagca atttttgatt tcagtcattg
    14641 aaaattgcaa tgcgtgacga ttcaacagca tttaagtgag tttcaggata tgggaaggac
    14701 atgaaaagag gagcgcaata aaatacacag gaagaagggg aaaatgtttc gtaaaaacag
    14761 aaaattaaca gcgcacatca ggaaacgcag tctcctgatt cagtgctacc acatgaaaat
    14821 ttagttaact gttaccgtac taaaatttat gtcagaagat gttccattac cgaaagtcaa
    14881 tcagcgatac aaagacgatc atggagcact ggccaccgta accagcgtcg aagaaacccg
    14941 agtggttttt atgcgggagg gttatccgca tccctgtatg cgaccgatgt acaactttct
    15001 gggaaaattc aaacccgacc cccgggaaga aacagaataa aacgaaatcc ctgccggcaa
    15061 tcacactgcc tgatggcagc ataatccact tattaattct catccccgga gacaagccct
    15121 gaaaaccact ccgggtgttc attgtatgcc gtgttcagcg catcccagga aacgttgata
    15181 taaaagctgt cctgcaattt gcgggtaacc acctctacca cccggttccg gttatacgcc
    15241 agtccggcat aacctctctc tgccagccac tcattcagtt catgttccag agacagattg
    15301 ataatatcgt aatcggacct tgccattccc gtttccttag cacatgtttt caggcacggg
    15361 gataaagtat aaagaatgtc gtactgctgc tgccagagca atattccccc tgatggttgt
    15421 atcagagatg gtatgccggt attttgcggg ttgttcccgt caggttatcg tgcacctcca
    15481 cggtcgttgt caccaccggc attccgctct gtcttagtct caggacatca gccgcaatac
    15541 gctgactgcc agaccagaac aggccgtcca gtgcggtcac cagtaacccc gcctccagcg
    15601 catacttcag ccgttcacgg ggcgctttca cttcccgggc aacctgctga tatggcaatg
    15661 atgtgttttc attcccaacc acgcgacgaa tacggtgaga cagatgatac cggtatgtat
    15721 ccggcacact ggaaagactg gccttcaggc tgtacacgca gccaaagcgt ttatcgttga
    15781 acaccacatt tttctggctg atgtcccatt cttcacgcag cacagcaatc agttgtggtg
    15841 tccgggtaag cagaaaggca attcaaaaca ggtgacgtaa tccacattca gcagggcaat
    15901 acgcggccgt ttttctgatc catttacaat cggatgtggg cgaacattat tatcattatc
    15961 tgaaaatctc cccctatggc atgtttgcca tggcggagag tcattgaagc ctttatgagg
    16021 ggtgaataca ttcctgaagc agtgcagtgg caaaaaaaca ccccgctttt attcattctc
    16081 tgacaataaa tattgagttt gactgtatca gattttaggt atttcctaga aaaggacttt
    16141 tttgctcaag gcaaaacaat accgcaaaat aatccttcac ctgcacaaac atcctcagtc
    16201 cattaaaaaa atcgccatgt taggttaacg acatcaaatt tggtcgttta ccatgattaa
    16261 ggtagttaca catggcccgc tattattttt cgtgccccaa aatttatttt ggtgaagagg
    16321 caataacctc tctatgccaa tttaataata aacgagtcgg tattgtcacc gatgatttta
    16381 tgatgtcatc aggtaaaact cgttatttaa taagccatat gcctgaggca tcggtatgca
    16441 ttttcggcga ggttactccg gatccagata ttgatattct gacttccggc gcggcgcgtt
    16501 ttaaagcctt taagcccgac gttattatcg ccctcggcgg cggctcgtcg ctggacgctg
    16561 cgaaaggaat taaagtcaca ttggaagagt attttggaga tcatcaaatc gatctcattg
    16621 ctattcccac aaccagcgga tccggctctg aagtgacgtc ctacgcgatc atctctgatc
    16681 cgcaaaatgg ccgcaaatat ccgttgatct ccgggcaact ggtgccggaa atcgctattc
    16741 tcgatcctaa cctagtgtta accgcgccgc gtcatgtcgc ggtagatacc ggcatggacg
    16801 tgctgaccca tgccattgaa gcctttgtct ctactggctc aaatgacttt agcgatgcgc
    16861 tggcggaaaa agccatcgcg ttgacctggc gctatctgcc gcaggtgttt aacgacgaaa
    16921 aagacattgc ggcgcgcacc cacatgcaca atgcctcctg tatggcaggc atggcattta
    16981 actccgccgg gctggggttg gtacacggca tggcacacgc catcggcggg atgctgcata
    17041 ttcctcatgg caaaattaac gccatgctgc tgccgattgt catcgacttc aacagcaaac
    17101 gggccagcac tgaaacccgc gatcgctatc accgttgcgc gcaaatcata ggcattgacc
    17161 atgcggtacc ggagcaggcc atcgcgctga tgactcagga gatccgccag atcaatcgcc
    17221 atttctgcat ccccgtcact ctcagcgaac tgggcatcga ccgtgcaaaa atcatcgagt
    17281 tgcgcagcgc actggtgaat tcgacgctgg ccgacggttg taccgcgtcg aacccgcggc
    17341 aggtgacgac gcatgatgtc gaagggttga tcgacctgat taccggctag ctggataact
    17401 ttgttcagcc tccgtgaagc agtcaaaaaa gtcctgctga taaacaaaaa ccgggcgtcg
    17461 ttactcccta tcctgatcgt tagacgccca ttacccataa gataacccaa taatcaggtc
    17521 gtacccatta tgaattacac cgaacaacaa gccgagtgga ttacccaaca aattttgcag
    17581 gaacttgcca ccagtgaaaa aacggcagcg cctgctgccg cgcccgtcgc gctgaatatt
    17641 ccggtgggcg tgtccaaccg ccatgttcat ctgtgccgtg aagatatgga cattctgttt
    17701 ggctacggct ctacgctaac ccgttctaaa gcgttgaaac agcccggtca gtatgccgcc
    17761 gaagagatgg tgacgctgcg cgggccaaaa ggcgagctca acaaagtgcg cgtgttaggg
    17821 ccactgcgta atgccacgca ggtggaaatc tctgtggccg acggctttgc gctgggcact
    17881 aaagctccgg tgcgcatgtc gggggatctg ctggattcgc cgggcattga aatcatcggt
    17941 ccgaaagggc gggtggtgaa acacaacggc atgattgtcg cctggcgcca tatccatatc
    18001 tcgcccgaag aagccgaact gcacggcctg catgacggaa tggaaatcga tgtgcaaaca
    18061 aacggtccgc gcggtggtgt gctcagccat gtagtggtac gcgtcacggc ggatgcagtg
    18121 ctggaactgc atattgatat ggaagaagct aacggcgtcg gtctgcgtaa tggcgatacc
    18181 gttcgcggca taaaacaggc tgcgcgccat ggctaacagc cccgaaaact gccgatttca
    18241 cgaattggcc gcgctgattg acagcggcga atgtcggccc tactccggcg cgttgaaggt
    18301 gggggggatc tcggtaccgc caatatcgca atcgtggtgc tggatgaaga taaccagccg
    18361 gtggcagggg taatgtatcc ctccaatgtg gtgaaagacg gcgtggtggt ggattacctg
    18421 accgccagcc gggtagtagc acgtctcaaa caaattcttg aacagaaaca gggctgcacg
    18481 ctggagcgcg cggcgatcgc agtcccaccg gggatctctg aaggcaacac aaaagtgatc
    18541 gtcaacgtag tggagttggc gggttttatc gtgacccaag tactagatga accggtagcc
    18601 gctgccagcg cgctgaatat taaaaacggg gcggtggtgg atgtcggagg aggcaccacc
    18661 ggcatgagca ttttgaaaag cggtaaagtg acgttcagtg ccgatgagcc caccggtgga
    18721 agccatatga agttggtgat cgctggcgcg ctgggcttgc cttatgccga ggcggaagaa
    18781 atgaaaaaaa acgggcagga agcgcaggtc tttaccctgg tgctaccggt ggcccagaaa
    18841 atggccagct tggtgtcggg atggttcgct acccagcagg taaaaaatat ttatttggta
    18901 ggtggcgcga gcagcttcag ccagtttgcc aacgtgttca gtaaacaaac cggtaaaaat
    18961 gtgattcctt cggcagagcc actattggtc acaccattag gcatcgccat gaatgcggac
    19021 caggggtaaa tcaatggaca atcaaacctt atcgcaactg ctggaccggg tcatcgctga
    19081 agtgttggca caatccgtcg cgcagaaaaa tgtctgcgta gtggtgactg gtgaggatat
    19141 ctcctcgctg ccggaaacgc tgaactgcct tgaggcgctt gagctggcgg gttatcagtt
    19201 gtgggtaaat ttttctcaca gcgccagcca gtcggcgctg aaatctgtct gcatggatgc
    19261 gctaattcag cgtggttctc gtgctggatt tgacagatcg ccgcctcact atgaggtgct
    19321 ctatctgcct gcgctctctg tcaacagcat gagcaaaatt gcgctgggca ttcgcgataa
    19381 tctggcctgt gaaactgtat ttcaggcgtt acagcaccgt aaacagatta tcgccacgct
    19441 gcatcaacaa tgcgtcgata gcgaattacc gatgccactg ctgtcttgtc tggaaggtta
    19501 cgctcaggtc ctagagagct atggcattac gcttttcggt aaacgtgcag cccatgtcaa
    19561 gtcggtgcaa ggaagccaat ccaccctgac agtagccggt aaaaaacgtt taatcaccca
    19621 gagcgatatc cgcctactga ccattggcac agtgctgcgc attgagagcg acacgctgat
    19681 tacccctgct gccagagatg aaatccagcg gcgtaatctc actgttatcc atggttaacc
    19741 ggaggaaata tgtacctcgc taaagttact ggcgcattgg tttccaccac caaacacgcc
    19801 tcgctgaatg gctcaaaact gctgatagtg gcgcggctcg atgaaaacta tcagccgact
    19861 gtccatgccc aggtggcagt tgatactgtc ggcgcgggca atggagagat tgtgatcatc
    19921 accaccggca gttcggcgcg tatgagcaac aacaaagatc actcggtgat tgacgctgcc
    19981 gtggtgggta tcgtcgactc gctcgaactt aacggttaat agcggcgcgt acgctgagga
    20041 atacttatgt ctgcgaatga ggcttcactc gacaactgga ttaacgaggc tattgccacg
    20101 cagttaccgg aactccggat gtcgctgagc ctggaggaca gtgaactgct ggcaaagttg
    20161 gtccgggaaa tggcacagtc cagcaatgta tcgatcgttt ttagcctagt ggatgcctgc
    20221 ggtcagcagc gttttttctt cagcatggat aacgccctgc tggtcagcca taccttggca
    20281 ccacaaaagg cctggaccgc ggtagctctc aaaatgccaa ctcacgaact ggcaacgctg
    20341 gtacagccgg gtggtgattt gtacggcctt gagaaagaaa aagatatctg ctgcttcggc
    20401 ggtggttttc cctgctggtc gggcaggcgc ttactaggcg gcatcggcat cagcggcggc
    20461 agtgttgagg aagatatgct catcgcccgc caggcgatgg cgcagtttag cgttctgcgt
    20521 tatcccctca caacaacccg ttaatttttt gcagtccatt tcagggggca tcatgtcttt
    20581 agcttgtgta ttagtgatta attgtggttc ctcatcaatg aaattctccg tcattcctca
    20641 ggatgcagat cagccgttgc tgtcgggcct agcggaacga ctgggtattg atcatgctgt
    20701 cataacgttt aaagaccgag acggccataa atccactgtc gcgctggatg acgccagcca
    20761 tcagcatgcg ctcaaagtgc tcttcgcgaa gctcgacgaa cagcaactgt tggaagccat
    20821 caacgccgtt gggcaccgcg tggctcatgg cggcagcgac ttcaaaagat cagtactggt
    20881 taccgatgat gtgatcgaaa aagtccgcgc gctgtcggtg ctggcccctt tgcataaccc
    20941 tgccaacctg attggtattg aagcggctcg ggctctgttg cccgcgttgc cgcatattgc
    21001 ggtgttcgat actgcgttcc accagacctt gtctccggct gcttacacct atgcgatccc
    21061 gctggagttc cagcaagatt atatggtgcg acgttacggc tttcacggaa catctcaccg
    21121 ctatattgcc gccgaggcgc ttgcatcact agatctcgac ccggcggatc atggcatcgt
    21181 gattgcccac ttgggcaacg gttcatcgct atgtgcggtg caaaacggca cgagcattga
    21241 cacctcaatg ggtatgaccc cgctggaagg gctggtaatg ggcacgcgct gcggggatct
    21301 tgattttggt gtcgtcgcat atctggcgaa acgcacaggt caaacgttcg acacgctgta
    21361 caaaatgctc aataaccagt ccggcctaat ggggatttcc ggcttatcca gcgattgccg
    21421 cacccttcag caggcgcgtg atgagggcca cgaacgggca gcgttagcca tcgacgtgtt
    21481 agtacatcgt ctcgcacgac atatcggcgg ccacgtgacc tcgcttaaac gcttcgatgc
    21541 gctgattttc accggtggaa ttggcgaaaa ctcggcgtta attcgagaac ttaccgtgca
    21601 acgccttcag gcgctgggat tggaactgga taaagaacgt aaccagcagc tgttcggcgg
    21661 acgtagcgga ctgatttcta aaaccgacac cacgaagatt gcggtcatcc caaccaatga
    21721 agaaaaaatg attgctatag atgcagcgga gattgcccgc acggcataac taattggcaa
    21781 aaatacgaca gttttaacag taattatgat cgctattcag agcggggcta ttttgcaagg
    21841 aagtttaaac gcagatcttt tattacaaac ctcgggtgga ttttattgtc aattgcggga
    21901 atgcaaaagc aagatagtcc cactgacgcg caaaacattt tgtctgaata accttagcat
    21961 tatgataatt aaataattaa tgcacatggg tgaatccgta gattgctatt cctctgtgca
    22021 cgttttcttt ctatcggaaa tattgaggtc gttatgcaac aagaagcatt aggaatggtt
    22081 gaaacgaaag gtctggtttc tgcaattgaa gctgcagata ccatggtgaa atctgccaac
    22141 gtgaccctag tgggttatga aaaaatcggc tccggcttgg tgactgtgat ggttcgcggc
    22201 gacgttggcg cagtgaaagc cgcgacagat gcgggctccg ctgctgcgag taaagtggga
    22261 gaactggtct ccgtacatgt tattccacgc ccacacattg aggtggaaaa aattctaccg
    22321 aaggctatcg gttaataaca ataaaggata ctgatcatga gagataatct tgttgagcag
    22381 attatatctg acgtaatgaa taaacaaacc gatatctcac cggaagctaa aacagcagcg
    22441 aatttcgctg gttgcggtat tacggaattt gtcggcactg cgttgggcca cactatcggc
    22501 ctagtgattg ccaatgttga taatcaattg catgaagtca tgaatatcga caagaaatat
    22561 cgctctatcg gtattcttgg cgcacgtact ggcgcaggcc cgcaaatttt tgcggctgac
    22621 gaagcgatta aagcaaccaa cagcgaaatt atttctattg agctggcccg cgataccgaa
    22681 ggaggtggcg gacacggttg cttaattatt tttggtgcgt ctgatgtttc cgacgtcagg
    22741 cgtgcggttg aagtggcgct gtctgaaatt gaacgcacca tgggtgacgt ttatggctcg
    22801 tcagccggac atcttgaatt ccagtacacc gctcgtgcca gctacgcgct gaataaagcg
    22861 ctgggtgcgc cgattggtaa atccttcggg atgacctgtg cctcgcctgc ggcgattggc
    22921 ctagtgattg ccgacgctgc ggcgaaatcc gccgtgattg acccggtggg ttatgccagc
    22981 ccgtcgcaag gcaccagctt tagtaacgaa gtgatcttca ccttctccgg tgattccggt
    23041 gcagtacgtc aggcggtgat tgccgcgcgt gaagtcggtc tacaactgct ctccacgtta
    23101 gatccggtgg aaattaaatc caccacgacg ccatatatct aagcatctga tgacgatgca
    23161 cgcggcgcgg tcggcagatg aagagtagta aggaatttaa agatgaatga tattgaaatc
    23221 gctcaggctg tctcgaccat tctgagcaaa ttcaccaaaa caacaccgga tgaagctccc
    23281 gccacgtcag aagcagcgcg ggtcgaaggg ttggatgaaa ttgtcgctaa ggcgttggcg
    23341 cagcactctt ccgtgcgcga cgccagtgcg atctctcagg tagcgaaggt agcgaatgct
    23401 agcactggag cattcgatac catggatgag gcgatttccg ccgccgtctt ggcacaggtg
    23461 cagtatcgcc actgttctat gcaagaccgc gcctcgttta tcaatggcat tcgcgatgtc
    23521 ttcctgcagg aagatgtgct gtgtgccctt tcccgtatgg cggtggaaga gaccggcatg
    23581 gggaattacg aggacaaact gatcaaaaac cgcgtcgcag cgctgaaaac gccaggtatc
    23641 gaagatctga ccaccagcgc ggtttccgga gacgggggtt taacgttgat cgaatactct
    23701 gcgttcggag tgattggttc gattacacca acgactaacc cgaccgaaac tattatcaac
    23761 aacagcatag gcatgctggc ggcaggcaac actgtggtgt tcagtccaca tccgcgctcg
    23821 cgcaaagtgt cgctgtacgc ggttgagctg atcaacaaca agcttgccca gttgggcgca
    23881 ccggcgaaca tggtggtaac ggtgaccaaa ccgtccatcg acaataccaa cgtcctgatc
    23941 aacgacccac gtatcaacat gctggtagcg actggcggtc cagccatcgt gaaaaccgtg
    24001 atgtcatcag gtaaaaaagc gattggtgca ggcgcaggta acccgccagc tgtggtagat
    24061 gaaacggcgg atatcgaaaa agcagcccgc gacatcatta agggctgtag cttcgacaac
    24121 aacctgccgt gcgtggcgga aaaagaggtg attgttgtga accaggtagc ggactatctg
    24181 attcactgca tgaagaaaag cggtgcctat ctgttgtgcg ataagaagtt aagtcaacaa
    24241 ctgcaatcgt tggtgcttaa tgaaaaaggc actgggccga ataccgcctt tgtcggcaaa
    24301 gatgcgcgct atatcctgca acaactggga atccaggttg gcgacgatat caaagtcatc
    24361 ttaattgagg ctgagaaaac acatccgttt gtggtgcatg agctgatgat gccggtcctg
    24421 ccggtggtgc gcgtagacaa tgttgatgaa gccattgagc tggcggtgaa agtggagcac
    24481 ggcaatcgtc ataccgcggt tatgcactcc accaacgtcg aaaagctgac caaaatggcg
    24541 cgcctgatcc agaccaccat ctttgttaaa aatggtccct cttatgcagg gctgggggtg
    24601 ggcggtgaag ggcatgccac ctttacgatt gccggaccga ccggcgaggg acttacgtca
    24661 gcgcgttcgt ttgcacgccg tcgtcgctgt gtaatggttg aagcgctgaa tattcgctaa
    24721 ctatcgcgaa gggtaactta aagatgaaaa aacgaatcat aaacgcaccg accccggata
    24781 ttttggctat gttgaaacgg cgtatgcccg gggagtttcg ttcgcgtttg gatttgattc
    24841 gcatcgacgc cattggtttg ttaatactgc cggttccgga tctctatttt tatgccgacg
    24901 tagccagtaa aagcgccaat gtggtggtat cagaaatctt tggcagttgc cctcagcata
    24961 tcaccacatt ggccattttt ggcgaagtcg cggcggtgca tgaagccatg cgaatcattg
    25021 aggaagacga taaccagttt tgagagtccg cttatgaaga agatattact tatcacaggc
    25081 gatttctctg aagactatga agtcatggtg ccatggcagg cattaaacat gttaggtttc
    25141 agagtggatg tagtgtgtcc gggaaaacgt accggcgagt ttattaaaac cgcgattcat
    25201 gattttgaag gtgatcagac ctacaccgaa aaacccggac atctttttag attaactgca
    25261 tcatttgatg acataaggtt acaggaatat agtggtgttt atatttctgg tgggcgttca
    25321 tcggaatact tgcgattaaa taagtcagta ttggatatcg tgcattacgc gatgaattta
    25381 acattacctg ttgctgcaat ttgtcatggc ccacaaattc tggccgctgc tggggtatta
    25441 aaaggccgga aactgacggg atattttacg gtaaaaccgg aagtggaaat ggcgggtggc
    25501 cagtgggtca ctgccgcaga tgatgaagcc attgtggatg gtaatttaat aaccgcgact
    25561 acctggatgg ggcatccagc aatattacgt cactttatta ctcaaatggg cactagcatt
    25621 attcattaat accctggcat ctccacaagg ttaacaaaat atattcggga gttttatatg
    25681 ttagagaaag gcttttctaa tccgacagac cgtgttgtaa gactgagaaa tatgatcctg
    25741 acggcgaagc cgtatgtgga atcagaacgc gcggtgttag caaccgaagc atataaagaa
    25801 acagaacaac tgcccgcgat tatgcgtcgt gctaaagtgg tggaaaaaat ctttaaccaa
    25861 ttaccggtaa caattcgccc agacgaatta atcgttggag cggtaactat taatcctcgc
    25921 tcaactgaaa tctgccctga gttctcctac gactgggtgg aaaaagagtt tgagactatg
    25981 gaacaccgta ttgccgaccc gtttgttatc ccgaaaaaga ctgctcagga gcttcatgaa
    26041 gcatttaaat actggccggg taaaactacc agtgctctgg cggcatctta catgtcagaa
    26101 ggcactaaag agagtatggc gagcggtgta ttcactgttg gtaactactt cttcgggggc
    26161 gtcggtcatg tcagtgttga ctacggtaaa gtgctgaaaa ttggtttccg tggtatcatt
    26221 aatgaagtta gccgtgcctt ggaatcatta gatcgcactg aaccaggata tataaagaaa
    26281 gaacagttct ataatgcggt gctgatcagt tataacgcag cgatccgttt cgcccatcgt
    26341 tacgctgaag aagcatcccg tctggcgcag caggagagca atccgacccg taaacgcgaa
    26401 ctggagcaga ttgctcaaaa ctgtactcgc gtgccggaat acggtgctac cacattctgg
    26461 gaagcatgcc agacattctg gtttattcag agcatgttac agattgaatc cagcggtcat
    26521 tctatctccc cggggcgttt cgaccagtat atgtacccgt atctggagtc ggacaaatct
    26581 atctcgcgtg aattcgcgca ggaactggtg gattgctgct ggatcaagct taacgacatt
    26641 aacaaaacgc gtgacgaagt ctctgcccag gcgtttgccg gttacgcagt gttccagaac
    26701 ctgtgctgtg gcggccagac agaagacggt cgcgacgcaa ctaacgatct gagctacatg
    26761 tgtatggaag cgactgccca tgtgcgtctg ccgcagccat ccttctcaat ccgcgtatgg
    26821 cagggtactc cggatgagtt tctgtatcgc gcttgcgagc tggtgcgtat gggcctgggc
    26881 gttccggcaa tgtacaacga tgaagtaatc atcccggcgc tgcagaaccg tggcatttcg
    26941 ctgcgtgatg cgcgtgatta ctgtatcatc ggctgcgtag agccgcaggc accgcatcgc
    27001 accgagggct ggcatgacgc cgcgttcttt aacgttgcaa aagtgctgga aatcaccctg
    27061 aacaacggtc gcgttggcaa taaacagcta ggcccagtga ctggcgaact gactcagttc
    27121 accagcatgg aggacttcta caccgcgttc cagaaacaga tggcgcactt cgttcatcaa
    27181 ctggttgaag cctgtaacag cgtggatatt gcccacggcg aacgctgccc gctgccgttc
    27241 ctatcagcac tggtcgacga ctgtatcggc cgtggtaaat ctctccagga aggcggggcg
    27301 atttacaact ttactgggcc gcaagcattc ggcgtagccg ataccggcga ctccgtctat
    27361 gccatccaga aacaggtatt cgaagatcgt aaactgtctt tgagcgaact gaaaagcgca
    27421 ctggacgcca acttcggtta tccggtgggt gcgaacccgc acactccagc ggcgaaatcc
    27481 tcgctcaacg agcaggatat ctacgatgtg gtgaaacgca tcattgaaca tcatggcgcg
    27541 ctggatccgg cagcgattaa aaacgaagtt tatcgccagc tgacttccgg cagtgcagca
    27601 ccggtgcaat ccggcactat gtcccgtcac gaggagatcc gtcgtattct ggaaaacaca
    27661 ccgtgcttcg gtaacgacat cgatgacgtg gatttagtag cgcgtaaatg tgcgctgatc
    27721 tactgccagg aagttgagaa atataccaac ccgcgcggtg gccagttcca ggctggtatc
    27781 tatccggtgt ctgcgaacgt gctgtttggt aaagacgttg ccgcactgcc ggatggccgt
    27841 ctggcgaaag agccgttggc ggatggcgta tctccacgtc agggtaaaga cacccttggc
    27901 ccaaccgccg cagccaactc agttgccaaa ctggatcact ttatcgcctc caacggtacg
    27961 ctctataatc agaaattcct gccgtcttct ttggctggcg agaacggtct gcgcaacttc
    28021 agcggcctga tacgtcacta cttcgataag aaagggatgc acgttcaatt taacgttatc
    28081 gaccgcaaca ctttgatcga agcccagaaa aatcctgagc aacatcagga tctggtggta
    28141 cgcgttgcgg gctatagcgc ccagtgggta gttttagcga aagaagttca ggacgacata
    28201 atcagccgta ctgagcaaca actgtcgtaa ataccagacg ggctatgtat caatatatag
    28261 cccgttactt tctccacgac ttctggttgt tacttttatc tgaaaaggta attcatctgg
    28321 taaatataga gtgatgttat gaataaagtt gagtacgaaa ccgaaggcgt catatttaat
    28381 attcaacgct attctttgca tgatggtcca ggcattcgaa ccattccttt ttttaaaggc
    28441 tgcccgctgt cctgcaaatg gtgtagtaat cctgaatcac aacgtcacag cccagagtta
    28501 ttatttaaaa agaatgattg catccgctgt gggaaatgta ttgatgcttg cccacaacag
    28561 gctctttcca ctactaatgc ctggtttatc aatcgcgacc gctgtattca gtgtgggaaa
    28621 tgtactgaga tttgccctac ccgtgcgctg gaaatgaagg gcaagcgtat gtcggtaacg
    28681 gcagtgatgc gcgaactgga aaaagaagag aatttatacc ggcgttcagg cggcgggatt
    28741 accctgtccg gtggtgaacc gctggcgcag ccggaatttg cccgcgagct gcttaaagcc
    28801 tgtaaagcca aaggctggca caccgctatt gaaacaagcg gcttcaccac caaagcggtg
    28861 attgatgagg tatttcccta tgtcgatctt gctctgaccg atattaaagc catcgatccg
    28921 gaaatccatg agcgcaacac cggcgtgaat aacagagtga ttctggagaa tctgctgcgc
    28981 atctcctttt taaccaaagt ggttgtgcgt attcctgtga tcccaggagt gaatgacaat
    29041 tcgcaggaaa tccataatat tgcggagttc gcccgcctga tgcagaacgt cgataccatt
    29101 cacttattgc cttatcacag cttcggtgaa aataaatata atctgcttgg tcgccagtat
    29161 ccgatgggcg atacaaaaag tatcgaagaa gcccaaatgg cagagttaaa agcaatggtt
    29221 gaatccttag gttttaactg ccatatcggc ggttaataaa agatgtaata agagtgcgaa
    29281 aaaatgctgc gcttgtttat ttgttacgca tgaatactat ttcaatttta aaaatataga
    29341 gcaatctgca ttacttatat tgtcatttga tttaattaca gaggtaagct agatgaatag
    29401 cttagatatt gtagttgcct tcggcggcgg catatttggt gcggctgttg gagcgctggc
    29461 ggcgtttgaa ttcgttgggc ttctggttat cgccatgacg gtagtgcaaa ttattaccgg
    29521 agcatcatcg gactttatta cttttccgtt tggactgttt ggcccgcaca ccggcggctt
    29581 tgccgctggg gttgcggcga cggcgtatgc agcgaagaaa ggcaagctgg gttccgggcg
    29641 tgatatcact gccgggttga gcggtctggc ggcttacgat gtgctgctgg taggcggggt
    29701 ttt
//
LOCUS       DADXDL010000064        26412 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.064, whole genome shotgun sequence.
ACCESSION   DADXDL010000064 DADXDL010000000
VERSION     DADXDL010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26412)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26412)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26412
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.064"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(520..1152)
                     /locus_tag="IRB70_003142"
     CDS             complement(520..1152)
                     /locus_tag="IRB70_003142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdX family protein"
                     /protein_id="HBC0633023.1"
                     /translation="MKRLIMATMVTAVLASSTVWAADNAPVAAQQQTQQVKQTQKTAA
                     AERISEQGLYAMRDVQVARLALFHGDPEKAKELTNEASALLSDDSTEWAKFAKPGKKT
                     NVNDDQYIVINASVGISESYVATPEKEAAIKIANEKMAKGDKKGAMEELRLAGVGVME
                     NQYLMPLKQTRNALADAQKLLDKKQYYEANLALKGAEDGIIVDSEALFVN"
     gene            1448..1723
                     /gene="ypdI"
                     /locus_tag="IRB70_003143"
     CDS             1448..1723
                     /gene="ypdI"
                     /locus_tag="IRB70_003143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis lipoprotein YpdI"
                     /protein_id="HBC0633024.1"
                     /translation="MKVNLMLFSLFLLVSIMACNVFAFSISGGGSEASYKETEKTSAM
                     TTTHSTKFQPSQAILLKMREDAPPLNLTEEIPPPFPTKANYLIHPVR"
     gene            complement(1800..2042)
                     /locus_tag="IRB70_003144"
     CDS             complement(1800..2042)
                     /locus_tag="IRB70_003144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfdY family protein"
                     /protein_id="HBC0633025.1"
                     /translation="MIYLWMFLALCIVCVSGYIGQVLNVVSAVSSFFGMVILAALIYY
                     FTMWLTGGNELVTGIFMFLAPACGLMIRFMVGYGRR"
     gene            2395..3315
                     /gene="lpxP"
                     /locus_tag="IRB70_003145"
     CDS             2395..3315
                     /gene="lpxP"
                     /locus_tag="IRB70_003145"
                     /EC_number="2.3.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311285.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid IV(A) palmitoleoyltransferase"
                     /protein_id="HBC0633026.1"
                     /translation="MFPQCKFSREFLHPRYWLTWFGLGVLWLWVQLPYPVLCFLGTRI
                     GTMARPFLKRRESIARKNLELCFPQHSAEEREKMIAENFRSLGMALVETGMAWFWPDS
                     RVRKWFDVEGLDNLKRAQMQNRGVMVVGVHFMSLELGGRVMGLCQPMMATYRPHNNQL
                     MEWVQTRGRMRSNKAMIGRNNLRGIVGALKKGEAVWFAPDQDYGRKGSSFAPFFAVEN
                     VATTNGTYVLSRLSGAAMLTVTMVRKADYSGYRLYITPEMEGYPADENQAAAYMNKII
                     EKEIMRAPEQYLWIHRRFKTRPVGESSLYI"
     gene            3671..3742
                     /gene="ypdK"
                     /locus_tag="IRB70_003146"
     CDS             3671..3742
                     /gene="ypdK"
                     /locus_tag="IRB70_003146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_077777854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein YpdK"
                     /protein_id="HBC0633027.1"
                     /translation="MKYFFMGISFMVIVWAGTFALMI"
     gene            complement(3807..5045)
                     /gene="alaC"
                     /locus_tag="IRB70_003147"
     CDS             complement(3807..5045)
                     /gene="alaC"
                     /locus_tag="IRB70_003147"
                     /EC_number="2.6.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine transaminase"
                     /protein_id="HBC0633028.1"
                     /translation="MADTRPERRFTRIDRLPPYVFNITAELKMAARRRGEDIIDFSMG
                     NPDGATPPHIVEKLCTVAQRPDTHGYSTSRGIPRLRRAISRWYQDRYDVEIDPESEAI
                     VTIGSKEGLAHLMLATLDHGDTVLVPNPSYPIHIYGAVIAGAQVRSVPLVEGVDFFNE
                     LERAIRESYPKPKMMILGFPSNPTAQCVELEFFEKVVALAKRYDVLVVHDLAYADIVY
                     DGWKAPSIMQVPGARDVAVEFFTLSKSYNMAGWRIGFMVGNKTLVSALARIKSYHDYG
                     TFTPLQVAAIAALEGDQQCVRDIAEQYKRRRDVLVKGLHEAGWMVEMPKASMYVWAKI
                     PEPYAAMGSLEFAKKMLNEAKVCVSPGIGFGDYGDTHVRFALIENRDRIRQAIRGIKA
                     MFRADGLLPASSKHIHENAE"
     gene            5422..7119
                     /gene="ypdA"
                     /locus_tag="IRB70_003148"
     CDS             5422..7119
                     /gene="ypdA"
                     /locus_tag="IRB70_003148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system sensor histidine kinase
                     YpdA"
                     /protein_id="HBC0633029.1"
                     /translation="MHEIFNMLLAVFDRAALMLICLFFLIRIRLFRELLHKSAHSPKE
                     LLAVTAIFSLFALFSTWSGVPVEGSLVNVRIIAVMSGGILFGPWVGIITGVIAGIHRY
                     LIDIGGVTAIPCFITSILAGCISGWINLKIPKAQRWRVGILGGMLCETLTMILVIVWA
                     PTTALGIDIVSKIGIPMILGSVCIGFIVLLVQSVEGEKEASAARQAKLALDIANKTLP
                     LFRHVNSESLRKVCEIIRDDIHADAVAITNTDHVLAYVGVGEHNYQNGDDFISPTTRQ
                     AMNYGKIIIKNNDEAHRTPEIHSMLVIPLWEKGVVTGTLKIYYCHAHQITSSLQEMAV
                     GLSQIISTQLEVSRAEQLREMANKAELRALQSKINPHFLFNALNAISSSIRLNPDTAR
                     QLIFNLSRYLRYNIELKDDEQIDIKKELYQIKDYIAIEQARFGDKLTVIYDIDEEVNC
                     CIPSLLIQPLVENAIVHGIQPCKGKGVVTISVAECGNRVRIAVRDTGHGIDPKVIERV
                     EANEMPGNKIGLLNVHHRVKLLYGEGLHIRRLEPGTEIAFYIPNQRTPVASQATLLL"
     gene            7134..7868
                     /gene="ypdB"
                     /locus_tag="IRB70_003149"
     CDS             7134..7868
                     /gene="ypdB"
                     /locus_tag="IRB70_003149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system response regulator YpdB"
                     /protein_id="HBC0633030.1"
                     /translation="MKVIIVEDEFLAQQELSWLIKEHSQMEIVGTFDDGLDVLKFLQH
                     NRVDAIFLDINIPSLDGVLLAQNISQFAHKPFIVFITAWKEHAVEAFELEAFDYILKP
                     YQESRITGMLQKLEAAWQQQQTSSTPAATVTRENDTINLVKDERIIVTPINDIYYAEA
                     HEKMTFVYTRRESYVMPMNITEFCSKLPPSHFFRCHRSFCVNLNKIREIEPWFNNTYI
                     LRLKDLDFEVPVSRSKVKEFRQLMHL"
     gene            7881..8738
                     /locus_tag="IRB70_003150"
     CDS             7881..8738
                     /locus_tag="IRB70_003150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0633031.1"
                     /translation="MKAPGLPADQQFFADLFSGLVLNPQLLGRVWFASQPASLPVGSL
                     CIDFPRLDIVLRGEYGNLLEAKQQRMVEGEMLFIPARAANLPVNNKPVMLLSLVFAPT
                     WLGLSFYDSRTTSLLHPARQIQLPSLQRGEGEAMLTALTHLSRSPLEQNIIQPLVLSL
                     LHLCRNVVNMPPGNSQPRGDFLYHSICNWVQDNYAQPLTRESVAQFFNITPNHLSKLF
                     AQHGTMRFIEYVRWVRMAKARMILQKYHLSIHDVAQRCGFPDSDYFCRVFRRQFGLTP
                     GEYSARFQG"
     gene            complement(8741..11236)
                     /gene="ptsP"
                     /locus_tag="IRB70_003151"
     CDS             complement(8741..11236)
                     /gene="ptsP"
                     /locus_tag="IRB70_003151"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBC0633032.1"
                     /translation="MLTIQFLCPLPNGLHARPAWELKEQCSQWQSEVTFINHRQNARA
                     DAKSSLALIGTGTLFNDSCSLNISGSDEEQARRVLEEYIQVRFIDSDSVQPTQAELTA
                     HPLPRSLSRLNPDLLYGNVLASGVGVGTLTLLQSDSLDSYRAIPASAQDSTRLEHSLA
                     TLAEQLNQQLRERDGESKTILSAHLSLIQDDEFAGNIRRLMTEQHQGLGAAIISNMEQ
                     VCAKLSASASDYLRERVSDIRDISEQLLHITWPELKPRNNLVLEKPTILVAEDLTPSQ
                     FLSLDLKNLAGMILEKTGRTSHTLILARASAIPVLSGLPLDAIARYAGQPAVLDAQCG
                     VLAINPNDAVSGYYQVAQTLADKRQKQQAQAAAQLAYSRDNKRIDIAANIGTALEAPG
                     AFANGAEGVGLFRTEMLYMDRDSAPDEQEQFEAYQQVLLAAGDKPIIFRTMDIGGDKS
                     IPYLNIPQEENPFLGYRAVRIYPEFAGLFRTQLRAILRAASFGNAQLMIPMVHSLDQI
                     LWVKGEIQKAIVELKRDGLRHAETITLGIMVEVPSVCYIIDHFCDEVDFFSIGSNDMT
                     QYLYAVDRNNPRVSPLYNPITPSFLRMLQQIVTTAHQRGKWVGICGELGGESRYLPLL
                     LGLGLDELSMSSPRIPAVKSQLRQLDSEACRELARQACECRSAQEIEALLTAFTPEED
                     VRPLLALENIFVDHDFSNKEQAIQFLCGNLGVNGRTEHPFELEEDVWQREEIVTTGVG
                     FGVAIPHTKSQWIRHSSISIARLVKPVDWQSEMGEVELVIMLTLGANEGMNHVKVFSQ
                     LARKLVNKNFRQSLFAAQDAQSILTLLETELTF"
     gene            complement(11261..12298)
                     /gene="ypdE"
                     /locus_tag="IRB70_003152"
     CDS             complement(11261..12298)
                     /gene="ypdE"
                     /locus_tag="IRB70_003152"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBC0633033.1"
                     /translation="MDLSLLKALSEADAIASSEQEVRQILLEEADRLQKEVRFDGLGS
                     VLIRLNESTGPKVMICAHMDEVGFMVRSISREGAIDVLPVGNVRMAARQLQSVRITTR
                     EECKIPGLLDGDRQGNDVSTMRVDIGARSCDEVMQAGIRPGDRVTFDTTFQVLPHQRV
                     MGKAFDDRLGCYLLVTLLRELHDAELPAEVWLVASSSEEVGLRGGQTATRAVSPDVAI
                     VLDTACWAKNFDYGAANHRQIGNGPMLVLSDKSLIAPPKLTAWIETVAAEIGVPLQAD
                     MFSNGGTDGGAVHLTGTGVPTVVMGPATRHGHCAASIADCRDILQMQQLLSALIQRLT
                     RETVVQLTDFR"
     gene            complement(12298..13383)
                     /gene="ypdF"
                     /locus_tag="IRB70_003153"
     CDS             complement(12298..13383)
                     /gene="ypdF"
                     /locus_tag="IRB70_003153"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBC0633034.1"
                     /translation="MTLLASLRDWLKAQQLDAVLLSSRQNKQPHLGISTGSGYVLISR
                     ESAHILVDSRYYVDVEARTQGYQLHLLDATHTLTTIARQIIADEQLQTLGFEGQQVSW
                     ETAHRWQSELNAKLVSATPDVLRQIKTPEEVEKIRLACGIADRGAEHIRRFIQAGMSE
                     REIAAELEWFMRQQGAEKASFDTIVASGWRGALPHGKASDKIVAAGEFVTLDFGALYQ
                     GYCSDMTRTLLVNGEGVSAESHPLFDVYQIVLQAQLAAISAIRPGVRCQQVDDAARRV
                     ITEAGFGDYFGHNTGHAIGIEVHEDPRFSPRDTTTLQPGMLLTVEPGIYLPGQGGVRI
                     EDVVLVTPQGAEVLYAMPKTVLLTGEA"
     gene            complement(13398..14645)
                     /locus_tag="IRB70_003154"
     CDS             complement(13398..14645)
                     /locus_tag="IRB70_003154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
                     /protein_id="HBC0633035.1"
                     /translation="MAIKKRSATVVPGASGAAAAVKNPQASKSSFWGELPQHVMSGIS
                     RMVPTLIMGGVILAFSQLIAYSWLKIPADIGIMDALNSGKFSGFDLSLLKFAWLSQSF
                     GGVLFGFAIPMFAAFVANSIGGKLAFPAGFIGGLMSTQPTQLLNFDPSTMQWATSSPV
                     PSTFIGALIISIVAGYLVKWMNQKIQLPDFLLAFKTTFLLPILSAIFVMLAMYYVITP
                     FGGWINGGIRTVLTAAGEKGALMYAMGIAAATAIDLGGPINKAAGFVAFSFTTDHVLP
                     VTARSIAIVIPPIGLGLATIIDRRLTGKRLFSAQLYPQGKTAMFLAFMGISEGAIPFA
                     LESPITAIPSYMVGAIVGSTAAVWLGAVQWFPESAIWAWPLVTNLGVYMAGIALGAVI
                     TALMVVFLRLMMFRKGKLLIDSL"
     gene            complement(14667..14993)
                     /locus_tag="IRB70_003155"
     CDS             complement(14667..14993)
                     /locus_tag="IRB70_003155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-like phosphotransferase enzyme IIB
                     component 1"
                     /protein_id="HBC0633036.1"
                     /translation="MSKKLIALCACPMGLAHTFMAAQALEEAAVEAGYEVKIETQGAD
                     GIQNRLTAQDIAEATIIIHSVAVTPEDNERFESRDVYEITLQDAIKNAAGIIKEIEEM
                     IASEQQ"
     gene            complement(15212..16177)
                     /gene="glk"
                     /locus_tag="IRB70_003156"
     CDS             complement(15212..16177)
                     /gene="glk"
                     /locus_tag="IRB70_003156"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucokinase"
                     /protein_id="HBC0633037.1"
                     /translation="MTKYALVGDVGGTNARLALCDIASGEISQAKTYSGLDYPSLEAV
                     IRVYLEEHKVEVKDGCIAIACPITGDWVAMTNHTWAFSIAEMKKNLGFSHLEIINDFT
                     AVSMAIPMLKKEHLIQFGGAEPVEGKPIAVYGAGTGLGVAHLVHVDKRWVSLPGEGGH
                     VDFAPNSEEEGIILEILRAEIGHVSAERVLSGPGLVNLYRAIVKADNRLPENLKPKDI
                     TERALADSCTDCRRALSLFCVIMGRFGGNLALNLGTFGGVFIAGGIVPRFLEFFKASG
                     FRAAFEDKGRFKEYVHDIPVYLIVHDNPGLLGSGAHLRQTLGHIL"
     gene            16381..17637
                     /locus_tag="IRB70_003157"
     CDS             16381..17637
                     /locus_tag="IRB70_003157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ion channel protein"
                     /protein_id="HBC0633038.1"
                     /translation="MLHPRARTMLLLSLPAVAIGIASSLILIVVMKIASVLQNLLWLR
                     LPGTLGIAQDSPFWIIAILTLTGIAVGLVIRFSQGHAGPDPACEPLIGAPVPPSALPG
                     LIVALILGLAGGVSLGPEHPIMTVNIALAVAIGARLLPRVNRMEWTILASAGTIGALF
                     GTPVAAALIFSQTLNGSSEVPLWDRLFAPLMAAAAGALTTGLFFHPHFSLPIAHYGQM
                     EMTDILSGAIVAAIAIAAGMVAVWCLPRLHAMMHQIKNPVLMLGVGGFILGILGVIAG
                     PVSLFKGLDEMQQMVANQAFSTSDYFLLAVIKLAALVVAAASGFRGGRIFPAVFVGVA
                     LGLMLHEHVPAVPAAITVSCAILGIVLVVTRDGWLSLFMAAVVVPNTTLLPLLCIVML
                     PAWLLLAGKPMMMVNRPKQQPPHDNV"
     gene            17752..18078
                     /locus_tag="IRB70_003158"
     CDS             17752..18078
                     /locus_tag="IRB70_003158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2502 domain-containing protein"
                     /protein_id="HBC0633039.1"
                     /translation="MFRSLFLAAALMAFTPLAANAGEITLLPSIKLQIGDRDHYGNYW
                     DGGHWRDRDYWHRNYEWRKNRWWRHDNGYHRGWDKRKAYERGYREGWRDRDDHRGKGR
                     GHGHRH"
     gene            complement(18219..19457)
                     /locus_tag="IRB70_003159"
     CDS             complement(18219..19457)
                     /locus_tag="IRB70_003159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBC0633040.1"
                     /translation="MTNYRVESSSGRAARKMRLALMGPAFIAAIGYIDPGNFATNIQA
                     GASFGYQLLWVVVWANLMAMLIQILSAKLGIATGKNLAEQIRDHYPRPVVWFYWVQAE
                     IIAMATDLAEFIGAAIGFKLILGVSLLQGAVLTGIATFLILMLQRRGQKPLEKVIGGL
                     LLFVAAAYIVELIFSQPNLAQLGKGMVIPSLPTSEAVFLAAGVLGATIMPHVIYLHSS
                     LTQHLHGGSRQQRYSATKWDVAIAMTIAGFVNLAMMATAAAAFHFSGHTGVADLDEAY
                     LTLQPLLSHAAATVFGLSLVAAGLSSTVVGTLAGQVVMQGFIRFHIPLWVRRTVTMLP
                     SFIVILMGLDPTRILVMSQVLLSFGIALALVPLLIFTSDSKLMGDLVNSKRVKQTGWV
                     IVVLVVALNIWLLVGTALGL"
     gene            19793..20995
                     /gene="nupC"
                     /locus_tag="IRB70_003160"
     CDS             19793..20995
                     /gene="nupC"
                     /locus_tag="IRB70_003160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside permease NupC"
                     /protein_id="HBC0633041.1"
                     /translation="MDRVLHFVLALAVVAILALLVSSDRKKIRIRYVIQLLVIEVLLA
                     WFFLNSDVGLGFVKGFSEMFEKLLGFANEGTNFVFGSMNDQGLAFFFLKVLCPIVFIS
                     ALIGILQHIRVLPVIIRAIGFLLSKVNGMGKLESFNAVSSLILGQSENFIAYKDILGK
                     ISRNRMYTMAATAMSTVSMSIVGAYMTMLEPKYVVAALVLNMFSTFIVLSLINPYRVD
                     ASEENIQMSNLHEGQSFFEMLGEYILAGFKVAIIVAAMLIGFIALIAALNALFATVTG
                     WFGYSISFQGILGYIFYPIAWVMGVPSSEALQVGSIMATKLVSNEFVAMMDLQKIAST
                     LSPRAEGIISVFLVSFANFSSIGIIAGAVKGLNEEQGNVVSRFGLKLVYGSTLVSVLS
                     ASIAALVL"
     gene            complement(21044..23233)
                     /locus_tag="IRB70_003161"
     CDS             complement(21044..23233)
                     /locus_tag="IRB70_003161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor domain-containing phosphodiesterase"
                     /protein_id="HBC0633042.1"
                     /translation="MFVEHNLIKNIKIFTLAFTLTVVLIQLSRFISPLAVIHSSYIFL
                     AWMPLCVMLSILFIFGWRGVVPILCGMFCTNLWNFHLSFLQTAVMLGSQTFVVLCACA
                     ILRWQLGTRWRYGLTSRYVWQRLFWLGLVTPIGIKCSMYLVGSFFDFPLKISTFFGDA
                     DAIFTVVDLLSLFTAVLIYNMLFYYLTRMIVSPHFAQILWRRDIAPSLSKEKRAFTLS
                     WLAALSVLLLLMCTPYENDFIAGYLVPVFFIIFTLGVGKLRYPFLNLTWAVSTLCLLN
                     YNQNFLQGVLTEYSLAFILAVLISFSVCLLYMVRIYHRSEWLNRRWHLQALTDPLTLL
                     PNFRALEQAPEQEAGKSFCCLRIDNLEFMSRHYGLMMRVHCIRSIYRTLLPLMQENEK
                     LYQLPGSELLLVLSGPETEGRLQHMVNILNSRQIHWNNTGLDMGYGAAWGRFDGNQET
                     LQPLLGQLSWLAEQSCAHHHVLALDSREEMVSGQTTKQVLLLNTIRTALDQGDLLLYA
                     QPIRNKEGEGYDEILARLKYDGGIMTPDKFLPLIAQFNLSARFDLQVLESLLKWLATH
                     PCDKKGPRFSVNLMPLTLLQKNIAGRIIRLFKRYHISPQAVILEITEEQAFSNAESSM
                     YNIEQLHKFGFRIAIDDFGTGYANYERLKRLQADIIKIDGVFVKDIVTNTLDAMIVRS
                     ITDLAKAKSLSVVAEFVETQQQQALLHKLGVQYLQGYLIGRPQPLAD"
     gene            complement(23441..23516)
                     /locus_tag="IRB70_003162"
     tRNA            complement(23441..23516)
                     /locus_tag="IRB70_003162"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23481..23483),aa:Ala,seq:ggc)
     gene            complement(23556..23631)
                     /locus_tag="IRB70_003163"
     tRNA            complement(23556..23631)
                     /locus_tag="IRB70_003163"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(23596..23598),aa:Ala,seq:ggc)
     gene            23852..24211
                     /locus_tag="IRB70_003164"
     CDS             23852..24211
                     /locus_tag="IRB70_003164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HBC0633043.1"
                     /translation="MFKERMTPDELARLTGYSRQTINKWVRKEGWTTSPKPGVQGGKA
                     RLVHVNEQVREYIRNAERPESQGEAPALSGDAPLEVLLVTLAKEMTPVEQKQFTSLLL
                     REGIIGLLQRLGIRDSK"
     gene            24213..24605
                     /locus_tag="IRB70_003165"
     CDS             24213..24605
                     /locus_tag="IRB70_003165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416898.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding transcriptional regulator"
                     /protein_id="HBC0633044.1"
                     /translation="MKRLRNKMTTEELAECLGVAKQTVNRWIREKGWKTEKFPGVKGG
                     RARLILVDTQVCEFIQNTPAFHNTPMLLEAEEPLAEYAPGIRTPAYRQIISAIDNMTH
                     SEQEKVAQFLSREGIRNFLARLDIDESA"
     gene            complement(24658..26073)
                     /gene="gltX"
                     /locus_tag="IRB70_003166"
     CDS             complement(24658..26073)
                     /gene="gltX"
                     /locus_tag="IRB70_003166"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBC0633045.1"
                     /translation="MKIKTRFAPSPTGYLHVGGARTALYSWLFARNHGGEFVLRIEDT
                     DLERSTPEAIEAIMDGMNWLSLEWDEGPYYQTKRFDRYNAVIDQMLEEGTAYKCYCSK
                     ERLEALREEQMAKGEKPRYDGRCRHSHEHHADDEPCVVRFANPQEGSVVFDDQIRGPI
                     EFSNQELDDLIIRRTDGSPTYNFCVVVDDWDMEITHVIRGEDHINNTPRQINILKALK
                     APVPVYAHVSMINGDDGKKLSKRHGAVSVMQYRDDGYLPEALLNYLVRLGWSHGDQEI
                     FTREEMIKYFTLNAVSKSASAFNTDKLLWLNHHYINALPPEYVATHLQWHIEQENIDT
                     RNGPQLADLVKLLGERCKTLKEMAQSCRYFYEDFAEFDADAAKKHLRPVARQPLEVVR
                     DKLTAITDWTAENVHHAIQATADELEVGMGKVGMPLRVAVTGAGQSPALDVTVHAIGK
                     TRSIERINKALAFIAERENQQ"
     gene            26332..26407
                     /locus_tag="IRB70_003167"
     tRNA            26332..26407
                     /locus_tag="IRB70_003167"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:26365..26367,aa:Val,seq:tac)
BASE COUNT         6584 a         6906 c         6459 g         6463 t
ORIGIN      
        1 gttgacatag caatacctat tagttaatta aatatgtgtt aatttagcgt ttatttaaga
       61 cataacgcct ctataaataa tccgcaaaat atcgtcgtag ctgcactcga tatttttaaa
      121 ttcctgtatc aagtactgaa aatcatttca tcgctacttc caattccttt ctgcatggta
      181 agtagtgagg acgaaaagaa gaatatgata aatattggtt cgcggtaatc agagagagcc
      241 gcgacatttg tgatgttatt cttacaactg taagaagcgc cagtgattta caagtaaggg
      301 tatgattacg ctttttaaag cgtaccataa aacataacat aataaatgat ttgtgataac
      361 acgggattat tgcggtttac tttgaggaag ataaaattcg agtttataga accgcgagcg
      421 ccaaataatt ttatggccac aacctgtcgt attgtggcca taaaaaattg tcggctggag
      481 ggagtaaaat cctttacctc aatatattgc ctgtcagctt tagttcacaa acagtgcttc
      541 gctatcgacg atgattccat cttccgcacc tttaagcgcc aggtttgcct cgtagtattg
      601 ctttttatca agcagtttct gcgcatcagc aagtgcatta cgagtctgtt taagcggcat
      661 cagatattgg ttttccatta caccaacacc ggccaggcga agctcttcca ttgcgccctt
      721 tttatcccct ttcgccattt tttcgttggc aatttttatc gcggcttctt tttcgggtgt
      781 cgctacataa ctctcagaaa ttccgacaga tgcattaatg acaatatatt ggtcatcatt
      841 gacattggtc tttttacctg gctttgcgaa ctttgcccat tcggtactat catcagacag
      901 caaagcggaa gcttcgttgg tcagttcttt tgccttttcc ggatcgccat gaaacagagc
      961 caggcgcgct acctgcacgt cacgcatcgc atataaacct tgttcagaga tacgctctgc
     1021 tgctgccgtt ttctgggttt gcttaacttg ctgagtttgc tgttgtgccg ctaccggtgc
     1081 attatcagca gcccatacag ttgaagatgc cagaactgct gtgaccatcg tagccataat
     1141 taaacgtttc atacttacct cattctttaa cagttttaga aaacaccgcc atcatattgg
     1201 gtgagcatga aatgagaaat cagagagcaa cggtcatttt gaaagggtta tcttacagtt
     1261 gtagttatta tcgcaagaag tattttagtc ttacaattgt aggaatatgc ttcctgtcac
     1321 agagaactat tcttatatac caaaaagaga tgtcatttat tatatcgatg taaatactga
     1381 ttaattatat gtaaatacag caataacgtc gtaggttttc agtgaaccat tttcaggata
     1441 actttctatg aaagtaaact taatgctttt tagcttattt ttattggtct ctattatggc
     1501 atgcaatgtt tttgcatttt ctatttctgg tggtggtagt gaggcgagct ataaagagac
     1561 agaaaaaacg tcagcgatga cgacaactca ctctacaaaa tttcagccat cacaggcgat
     1621 tttgttaaaa atgagagaag atgcgccacc attaaacctc acagaagaaa ttccgccccc
     1681 ttttccgaca aaggcgaatt atcttatcca tcctgtgcga tagcgtctgt cacacggcag
     1741 gtgaacaatc atgtctgatg ctgatgtgaa cacctgccca aatgatccat cctgaactac
     1801 taccgcctgc cataccccac cataaagcga atcatcaagc cacaagccgg ggcaagaaac
     1861 ataaatatcc ccgtcactag ttcattaccg ccagttaacc acatggtgaa gtagtaaatg
     1921 agtgcagcga ggatcaccat gccgaagaaa gaagagaccg ccgagaccac gttcagtacc
     1981 tgaccgatgt atccgcttac gcagacaata cacagggcga gaaacatcca taaataaatc
     2041 atagctcaac ctcctgccgc gctaaaaaac ctgtaacttc agtcacttta atagtaagac
     2101 aatccttaac ctctggcaat ttttgctaag catcaatgaa aacagcacgt taaatgcaac
     2161 gctattgcgt gcggaaaact ttttactttg cacgattaat aatcagtagc tgaaagcagt
     2221 cagccagtga taaagtagag ccaccgcatt catgctcctc gtggttatgt cctgactagt
     2281 ctttacactc tttacaggaa ccattgtcgt acatgatggc ccaaccaatt gagtgtaccg
     2341 ctgtcgacat ggaatcttct gcgatacaac aattcgtatc tacagaaggt aactatgttt
     2401 ccacaatgca aattttcccg cgagtttctg catcctcgct actggctcac gtggtttggg
     2461 cttggtgtac tctggctttg ggtacagctt ccttatcctg ttctctgctt tctcggcacg
     2521 cgtatcggca caatggcgcg accattcctg aaacgtcgtg aatctatcgc ccgtaaaaac
     2581 ctggaacttt gcttcccaca gcattctgcg gaagaacgcg agaagatgat tgccgaaaac
     2641 tttcgttcac tcggcatggc gctggtagaa accggcatgg catggttctg gcccgacagt
     2701 cgcgtacgta aatggtttga tgttgaaggg ttggataacc ttaaacgcgc acaaatgcaa
     2761 aatcgcggcg taatggttgt cggcgtccat tttatgtcgc tggaactggg cggccgcgtg
     2821 atgggactgt gccaaccaat gatggccacc tatcgtccac ataataatca gctgatggaa
     2881 tgggtgcaga cccgtggtcg catgcgctct aacaaagcga tgatcggcag aaataatctg
     2941 cgcggcattg tcggtgcact gaagaaaggt gaagcggtat ggtttgctcc cgatcaggat
     3001 tatggtcgta aaggcagctc cttcgcgccg ttctttgcgg tggaaaatgt cgccacaacc
     3061 aatggcacct atgtcctctc tcgtctctct ggcgcagcca tgttgaccgt aacgatggta
     3121 agaaaagcgg attacagcgg atatcgtttg tacatcaccc cagagatgga aggctacccg
     3181 gcagatgaaa atcaagccgc tgcctatatg aacaagatta tcgaaaaaga gatcatgcgc
     3241 gcaccggagc agtacctctg gatccaccgt cgctttaaaa cgcgcccggt gggagaatcg
     3301 tcgctataca tttaacaaac tgctcttact ctttccctcc tcaaatcagc cataataacc
     3361 tcatggtttt tatggctttt ttcttaaggt tttttccttc gctgaatctc taattattac
     3421 cgtcagaaat taaactgtcg ccgatatgag acacctgtaa gttactaaaa gtaaataaga
     3481 aaatgcctct tgtctcgttt cagttttagg cgtacattag cgccgtctgg agcagtttag
     3541 ctcagaattc tggggtgatg cccacggtaa aatacaggac ttttaaggtc gttttgcccg
     3601 gtgtcaactc actgtatcag gtgtaatgaa gtcattcagg cgtaacagta attacgcgga
     3661 gagatgtaaa gtgaaatatt tctttatggg catttctttt atggtcatcg tttgggccgg
     3721 tacttttgcc ctgatgatct aaaagcaaac tgtgcaatga aaaacaggag ccatctggct
     3781 cctgtttgca tttctgtcga tggtgtttat tccgcgtttt cgtgaatatg tttgctgctg
     3841 gcgggtagta aaccgtcggc acggaacatc gctttaattc cacgaatcgc ctggcgaata
     3901 cgatcgcggt tttcaatcag tgcaaagcga acatgggtgt cgccgtagtc gccaaagcca
     3961 atccctggag agacacagac cttcgcttcg ttaagcattt tcttggcaaa ttccagtgaa
     4021 cccatggccg catacggttc cgggattttc gcccagacat acatcgaagc cttcggcatt
     4081 tcgaccatcc agcccgcttc atgcagccct tttaccagta catcacggcg gcgtttgtac
     4141 tgttcggcaa tgtcgcgcac gcactgttga tcgccctcca gcgccgcaat cgctgccacc
     4201 tgcaacggcg taaaggtgcc gtaatcgtga tagcttttaa tacgtgccaa cgcgctgacc
     4261 agcgttttgt taccgaccat aaagccgata cgccagcccg ccatgttgta gcttttcgac
     4321 agcgtaaaga actcgactgc cacatcgcgt gcacctggca cctgcatgat tgacggcgct
     4381 ttccagccat cgtagacgat gtccgcatag gccaggtcat ggaccaccag cacatcgtag
     4441 cgtttcgcca gcgccactac tttttcgaag aactccagct ccacgcattg cgcggttggg
     4501 ttcgacggga agccgaggat catcatcttc ggttttggat aactttcgcg aatggcgcgt
     4561 tccagttcgt tgaagaaatc gacaccttcc accagcggca ctgagcgtac ctgcgccccg
     4621 gcaatcaccg cgccgtaaat atgaatcggg tagcttggat taggcaccag tacagtgtca
     4681 ccatgatcca gcgtcgccag catcagatgc gccaggccct ctttcgaacc aatagtgacg
     4741 atggcttctg attccgggtc gatttcaacg tcgtagcgat cctgatacca gcgggaaatg
     4801 gcgcgacgta gccgcggaat gccgcgtgaa gtggagtaac catgcgtgtc cgggcgctgg
     4861 gccaccgtac ataatttttc gacgatatgc ggcggagtcg caccgtccgg gttacccata
     4921 ctgaaatcga taatatcttc gccgcgccga cgcgcagcca ttttcagttc agcggtaatg
     4981 ttaaaaacgt agggcgggag acgatcaata cgcgtaaagc gacgttcagg gcgagtgtca
     5041 gccataatgt cctcagatta acgttagcgc ccggaccgtc cgagcgacgc tgccacgatg
     5101 gtggctgttt tgaaaatagc ctgattaatt tctgtctgtc cagcgtttta gaacattttt
     5161 atcaatggct ttaaatgagg aactccactt caaaaacagg aaatttatct gcgctaacaa
     5221 gaaaattacc actcatttta ttaacattat aatttcaata aatttaccaa gcagatgtgc
     5281 attatcaaga gatgcattgc taatacacca tttatccttc aacccccttt taaaattgtg
     5341 gtttttcctc aaaaacggcc tgctggtcat cagccttcag gttacctatc atagaggttt
     5401 aatccttatt cagagtcacc cgtgcacgaa atattcaaca tgctgctggc ggtcttcgat
     5461 cgggcagcgt taatgcttat ctgcctgttt tttctcatcc gtatccgcct gtttcgcgaa
     5521 ctgttgcaca agtcggcaca ctcaccgaaa gagctgctcg ccgttaccgc cattttctcg
     5581 ctgttcgccc tgttcagcac ctggtccgga gttcccgtag aaggctcgct ggtgaacgta
     5641 cgtattatcg cggtgatgtc aggcgggatt ctgtttggcc cgtgggtggg catcattacc
     5701 ggcgtgattg cgggtattca tcgttattta attgacatcg gcggcgtgac ggcgatcccc
     5761 tgctttatca ccagcattct ggcgggttgt atatcgggct ggatcaacct gaaaatcccc
     5821 aaagcacagc gctggcgcgt cggtattctc ggcggcatgt tatgtgaaac gttgaccatg
     5881 attctggtga ttgtctgggc accaactacc gcgttgggga tcgatatcgt ctctaaaatc
     5941 ggcattccaa tgatcctcgg tagcgtctgt atcggcttta ttgtgctgct ggtgcaaagc
     6001 gttgagggcg aaaaagaggc cagcgccgcg cggcaggcca agctggcgct ggatatcgcc
     6061 aacaaaacgc tgccgctgtt tcgccatgtc aatagcgagt cattacgcaa ggtctgcgaa
     6121 attatccgcg atgacattca cgccgatgcg gtggcgatta caaataccga tcatgtgctg
     6181 gcctatgttg gcgtgggtga gcataactat cagaatggcg atgatttcat tagcccgact
     6241 acccgccagg cgatgaatta cggaaaaatc atcattaaaa acaatgatga agcccaccgc
     6301 acaccagaga ttcattccat gctggtgatc ccattgtggg agaaaggcgt tgtgaccgga
     6361 acgctgaaaa tttactactg ccacgcgcat cagataacct cgtcattaca ggaaatggcg
     6421 gtcggtctgt cacaaatcat ctccacgcaa ctggaggttt cgcgcgctga gcagctgcgt
     6481 gaaatggcaa ataaggcaga gcttcgcgcc ctgcaaagca aaattaatcc ccatttcctg
     6541 tttaacgctt tgaacgctat ttcatcgtca atccgcctga atccggatac tgctcgccag
     6601 ctgatcttta atttgtcgcg ctatctgcgc tataacattg aattaaaaga tgatgagcaa
     6661 atcgatatca aaaaagagct gtatcaaatt aaagactata ttgccattga gcaggcccgc
     6721 tttggcgaca agctgacggt tatctatgat attgatgaag aggtgaattg ctgcattccc
     6781 agcctgctga tccagccgtt ggtggaaaac gccattgtcc acggtatcca gccttgcaaa
     6841 ggtaaaggcg ttgtcaccat cagcgttgca gagtgcggta atcgggtacg tattgcggtg
     6901 cgagataccg ggcacggcat cgatccaaag gtgattgagc gggtcgaagc gaatgaaatg
     6961 ccgggcaata aaattggcct gctgaatgtc catcatcgcg tgaagttatt gtatggcgag
     7021 gggctgcata tccgccgcct ggaaccagga acggaaattg cgttttacat tcctaaccaa
     7081 cgcaccccag tcgcctcaca ggctacctta ttgctttgag ccggagtgat attgtgaaag
     7141 tcatcattgt tgaagacgaa ttcctggcac aacaggaact gagctggcta attaaagagc
     7201 acagccagat ggagattgtc ggcacctttg acgacggtct ggacgtgttg aagtttttgc
     7261 agcataaccg cgtcgacgcc atttttctgg atatcaatat tccgtcgctg gatggtgtgt
     7321 tgctggcaca aaacatcagc cagttcgccc ataaaccgtt tattgtgttt atcaccgcgt
     7381 ggaaagaaca tgcggtagaa gcgtttgaac tggaggcgtt tgactacatt ctcaaaccgt
     7441 atcaggagtc acgcattacc gggatgctgc aaaaactgga agcagcctgg caacaacagc
     7501 agaccagcag tacgcctgcc gcgacggtaa cgcgtgagaa tgacaccatt aatctggtga
     7561 aagatgagcg aatcatcgtc acgcccatta acgatatcta ttacgccgaa gcgcatgaga
     7621 aaatgacctt tgtctatacg cggcgtgaat cctacgtaat gccgatgaac attaccgagt
     7681 tttgcagcaa gctgccgccg tcgcattttt tccgctgcca tcgctcattt tgtgtcaatc
     7741 tgaacaaaat ccgcgagatc gaaccgtggt ttaataacac ctatattctg cggctgaaag
     7801 atctggattt tgaagtgccg gtcagccgca gcaaagttaa agaattccgc cagttaatgc
     7861 atctttaatc gggaactttc atgaaagcac caggcttgcc cgccgatcaa caatttttcg
     7921 ccgatctgtt cagcggcctg gtgcttaacc cgcaactact ggggcgcgtc tggtttgcca
     7981 gccagcctgc ctcattgcca gtgggcagtt tatgtattga ttttccccgt ctggatatcg
     8041 tgctacgcgg cgaatacggc aacctgctgg aagcaaagca gcagcgaatg gtggaaggag
     8101 aaatgctgtt tattccggcg cgcgcggcta atttaccggt caacaacaaa ccggtgatgc
     8161 tgttaagcct ggtgttcgca ccgacctggc ttgggttatc gttttacgat agccgcacca
     8221 cgtcgttgtt gcatcctgcc cgccagatcc agcttcccag cctgcaacgc ggtgaaggtg
     8281 aagcgatgct taccgccctc acccatctta gccgttcgcc gctggagcag aatatcattc
     8341 agccactggt gttaagtttg ctgcatcttt gccgtaacgt ggtgaatatg ccgccgggca
     8401 attcgcagcc gcgcggcgat tttctctatc acagcatttg taactgggtt caggataatt
     8461 atgcccagcc gctcacccgc gagagcgtgg cgcagttttt taatatcacg cccaatcatc
     8521 tgtcaaaact gtttgctcag catggaacaa tgcgttttat cgagtatgtt cgctgggtac
     8581 gaatggcaaa ggcaaggatg attttgcaga aatatcatct gtcgattcat gatgtggcac
     8641 agcgttgcgg ttttccggac agcgactatt tttgtcgcgt tttccggcgt cagtttggcc
     8701 tgacgccggg agagtacagc gcccgttttc agggctaacg tcagaaggtt aattccgttt
     8761 ccagcagcgt caggatgctt tgcgcatctt gcgcggcaaa caacgactgg cggaagtttt
     8821 tattcaccag tttgcgcgcc agctgcgaga agactttcac atgattcatc ccttcgttag
     8881 cgcccagtgt cagcatgatc accagttcga cttcgcccat ttctgactgc cagtcaaccg
     8941 gtttcaccag ccgggcaatg ctgatactgg aatgacggat ccactgagat ttggtgtgcg
     9001 ggatcgctac gccaaaacca acgccggtgg taacaatctc ttcccgctgc cagacatctt
     9061 cttccagctc aaacggatgt tcagtacgcc cgttaacacc aaggttgccg cacaggaact
     9121 ggatcgcctg ctctttatta ctaaagtcat gatcaacaaa gatattctcc agcgccagca
     9181 gtgggcgaac gtcttcttcc ggcgtaaagg cggtgagtaa cgcttcaatc tcctgcgcgc
     9241 tgcggcattc acatgcctga cgcgccagtt cccgacacgc ctcgctatcc agttgacgaa
     9301 gctggctttt caccgccgga atgcgcgggc tactcatact cagctcgtct aggcccagcc
     9361 caagcagtag cggaagataa cggctttcac cgcccagttc accgcaaata cctacccatt
     9421 taccccgctg atgcgcagtg gtaacaatct gctgcaacat gcgcaggaac gatggcgtaa
     9481 tcgggttata cagcggcgat acgcgcgggt tattacgatc gaccgcatac agatactggg
     9541 tcatatcgtt ggagccgata ctgaagaaat cgacctcatc gcagaagtga tcgatgatgt
     9601 agcacaccga cggcacttcc accatgatac ccagcgtaat cgtctctgca tgacgcaggc
     9661 catcgcgctt aagctcaacg atcgcttttt ggatctcgcc cttcacccat aagatctgat
     9721 cgaggctgtg aaccatcggg atcatcaact gggcgttgcc gaaactggcg gcgcgcaaaa
     9781 tggcccgcag ttgagtgcga aacaggccag caaattccgg gtaaatacgt accgcgcgat
     9841 agccgaggaa cgggttctct tcctggggaa tattcagata aggaatgctt ttatcgccgc
     9901 cgatgtccat cgtgcggaag ataatcggct tgtcgcccgc cgccagtagc acctgctggt
     9961 aggcttcaaa ttgctcctgc tcgtccggcg cgctgtcgcg atccatatag agcatttcgg
    10021 tacggaacag cccgacacct tccgcgccgt tggcaaacgc gcctggcgct tccagagcgg
    10081 tgccgatatt cgccgcaata tcaatacgct tgttatcacg ggaataggcc agctgcgcgg
    10141 cggcctgcgc ctgttgtttt tggcgtttat ccgccagcgt ctgcgcgacc tgataataac
    10201 cgctcaccgc gtcattcggg ttaatcgcca gcacgccgca ctgggcgtca agcactgccg
    10261 gttgcccggc atagcgcgcg atcgcatcca gcggcaagcc actcagtacc gggatcgccg
    10321 aggcacgggc cagaatcagg gtatgcgagg tgcgcccggt tttctccaga atcatgcccg
    10381 caagattttt taaatcgagg ctcaaaaact ggcttggggt taaatcttca gccaccagaa
    10441 tagtcggttt ttccagcacc agattgttgc gcggtttcag ttccggccag gtgatatgca
    10501 gcaactgttc gctgatatcg cgaatgtcgc tgacccgctc gcgcagataa tcactggcag
    10561 aagcagatag tttggcgcaa acctgctcca tattgctgat gatcgctgca cccagcccct
    10621 gatgttgttc tgtcatcagg cgacggatat tgcctgcaaa ttcatcatcc tgaatcagcg
    10681 acaaatgggc gctgagaatg gttttgcttt cgccgtcacg ctcgcgcaat tgctggttca
    10741 gttgctcggc aagcgttgcc aggctgtgct ccagccgggt ggaatcttgc gcactggcgg
    10801 ggatcgcccg gtaactgtcg aggctgtcgc tctgtaacag ggtcagcgta cccacgccaa
    10861 cgccgcttgc cagcacgttg ccgtacagta aatccgggtt caggcggctt aatgaacgcg
    10921 gcagcggatg cgccgtcagt tctgcctgcg ttggctggac gctgtcgctg tcgataaagc
    10981 gcacctggat gtactcttcc agcacgcgcc gcgcctgctc ttcatcgctg ccgctaatgt
    11041 tcaggctgca actgtcatta aatagggtgc cggtgccaat cagcgccagc gagcttttgg
    11101 catcagccct ggcgttctgg cgatgattaa taaaggtgac ttcactttgc cactggctgc
    11161 actgctcttt aagttcccac gccggacgag catgcagacc gtttggcaaa ggacagagaa
    11221 attgaatcgt taacataacc gctccgggtt aatcaggaga tcatctgaaa tccgtcagtt
    11281 gaacaaccgt ctcacgggta agacgttgaa taagggcaga taaaagctgc tgcatctgca
    11341 aaatgtcgcg gcagtcggca atcgatgcgg cgcaatgtcc gtggcgggtt gctggcccca
    11401 tcaccactgt gggtacgcca gtgccggtta aatgcaccgc cccgccgtcc gttccgccgt
    11461 tgctgaacat atcggcctgc aacggcacgc caatttctgc cgccacggtt tcaatccacg
    11521 cggtaagttt tggcggcgca atcagcgact tgtcgcttaa caccagcatc ggcccgttac
    11581 caatctggcg atggttagcc gcgccataat caaagttttt cgcccagcag gcggtatcaa
    11641 gcacaatggc gacatccggc gacaccgcgc gggtggcagt ttgcccgccg cgtaatccca
    11701 cctcttcgct ggaacttgcc accagccaca cttccgcagg cagttcggcg tcgtgcagct
    11761 cacgcagtaa cgtcaccagc agatagcaac cgaggcggtc atcaaaggct ttccccatta
    11821 cccgctggtg agggagaacc tgaaaagtgg tatcaaaggt gacgcgatcg cctggacgaa
    11881 ttcccgcctg catcacttcg tcacacgagc gcgcgccaat gtccacgcgc atggtgctga
    11941 cgtcattccc ctgccggtcg ccgtcaagca ggcctggaat tttgcactct tcacgggtag
    12001 tgatacgcac cgactgaagc tggcgggcag ccatgcgtac attgccaacc ggcaacacat
    12061 cgatcgcccc ttcgcgggag atgctgcgca ccataaatcc cacttcgtcc atatgcgcac
    12121 agatcatcac cttcggacct gtcgattcat tgaggcggat cagcaccgat cccaggccgt
    12181 caaatcgcac ttctttttgc aggcgatccg cttcttccag caggatctgc cgtacttcct
    12241 gttccgagga ggcgatcgca tctgcctcgc tcaacgcttt taataacgat aaatccatta
    12301 tgcctctccc gtgagcaaca ctgttttcgg catggcgtag agcacttctg cgccttgcgg
    12361 ggtgaccagc acaacatctt cgatgcgcac gcccccttgc cctggcaaat aaatccccgg
    12421 ctccacggtc agtaacatgc ctggctgtag cgtcgtggtg tcccgcggtg aaaaacgcgg
    12481 atcttcatgg acttcaatgc cgatagcatg accggtgtta tgaccgaaat agtcgccaaa
    12541 tccagcctcg gtaatcaccc ggcgcgcggc gtcgtcaacc tgctggcagc gcacgccggg
    12601 gcgaatcgcg gagattgccg ccagctgtgc ctgcaaaaca atctgataga cgtcaaacag
    12661 cgggtgagat tcggcgctca ccccttcgcc attcaccagc aaggtgcgtg tcatatcaga
    12721 gcagtagccc tgatagagcg caccgaaatc gagagtgaca aactcgcccg ctgcaacaat
    12781 cttgtcgctg gctttgccgt gcggcagcgc cccacgccag ccgctggcga caatggtatc
    12841 gaaagaggct ttttctgcgc cctgctggcg cataaaccac tccagttcag cggctatctc
    12901 gcgctcgctc atccccgcct gaataaagcg gcgaatatgc tcagcaccgc gatcggcaat
    12961 cccacaggcg aggcggattt tctccacctc ctctggcgtt ttgatttgcc gcagcacatc
    13021 cggcgtggcg ctaaccagtt tcgcattgag ttcagactgc cagcggtgcg cggtttccca
    13081 actcacctgc tggccctcaa aaccgagcgt ttgcaactgc tcatcggcaa tgatttgcct
    13141 ggcgatggtg gtcagcgtgt gcgtcgcatc aagcaaatgc agttggtagc cttgcgtgcg
    13201 ggcttctaca tctacgtaat agcgcgagtc caccagaatg tgcgcacttt cacggctaat
    13261 cagcacatag cctgatccgg tggagatccc cagatgcggc tgtttgttct gccgtgagga
    13321 gagaagcacc gcatccagtt gttgcgcctt aagccagtcg cgcagcgagg caagtaatgt
    13381 catcaggatt gtccttctta caggctatcg attaacaatt tgcctttgcg gaacatcatc
    13441 agacgcagga acaccaccat cagcgcagtt atgactgccc ccagcgcgat ccccgccatg
    13501 tagacgccga ggttagtgac cagcggccat gcccagatag cggactccgg gaaccattgc
    13561 actgcgccca gccagactgc agcggttgag ccgacaatcg cgccaaccat ataggacgga
    13621 atggcggtga tgggactttc cagtgcaaac ggaatcgcac cttcactgat ccccataaac
    13681 gccaggaaca tggcggtttt accctgcgga taaagctgag cactgaacag acgtttgccg
    13741 gttaaacggc ggtcgataat ggtcgccaga cccagaccaa tcggcggaat aacaatagcg
    13801 atggaacgcg cggtaaccgg taatacgtgg tcagtggtaa agctgaaggc aacgaaacca
    13861 gctgctttgt tgatcgggcc accaaggtcg attgctgtcg ccgcggcgat ccccatcgcg
    13921 tacatcagcg cgcccttctc acctgcggca gtcagcacgg tacggatacc gccgttgatc
    13981 cagccgccaa agggggtgat gacgtagtac atcgccagca tgacaaaaat ggcggaaaga
    14041 atcggtagca aaaatgtggt tttgaacgct aacaggaaat ccggtaactg gattttctgg
    14101 ttcatccact tcacaaggta accggcaacg atagatataa tcagggcacc aatgaaggtg
    14161 gacggtaccg gcgaagaggt cgcccattgc atagtgctgg gatcgaagtt cagcagttgc
    14221 gtcggctggg tagacatcaa cccgccgata aaaccagccg ggaacgccag tttgccaccg
    14281 atagagttcg ccacaaatgc agcaaacatc ggaatggcaa aaccaaacaa cacgccgccg
    14341 aaggactgcg acaaccaggc aaatttcagt aaggagaggt cgaaaccgga gaatttcccg
    14401 ctattaagag catccatgat gccgatatca gcaggaattt taagccagct ataagcaatc
    14461 agctggctga aagcgaggat cacaccgccc ataattaagg tcggcaccat gcgtgaaatc
    14521 cctgacatca catgctgcgg gagttcaccc cagaagctgc ttttagaggc ctgcggattc
    14581 ttaactgccg ctgccgcacc ggatgcgcca ggcacaacgg ttgcactgcg ttttttaatg
    14641 gccataacaa ttatccctgt cgaatattac tgttgttcag aggcaatcat ctcttcgatt
    14701 tctttgatga tgcccgcagc gtttttaatt gcgtcctgca aagtgatttc ataaacgtcg
    14761 cgtgattcga aacgttcgtt atcttccggg gtaaccgcca cggagtggat gatgatggtc
    14821 gcttcggcga tatcctgcgc ggtcaggcga ttctggatac cgtccgcgcc ctgagtttca
    14881 attttcactt catagcctgc ttccaccgcc gcttcttcca gcgcctgggc tgccataaag
    14941 gtgtgagcca gacccatcgg gcaggcacat aaagcaatca gtttcttact catcgttaat
    15001 tcctcgttca gtgatagttg acgagtgaaa ttatgaacgt gcaaaacaaa tcgccgttac
    15061 cagacaaata atgcatttac tggagaatta atcccgctgt acggaagtgt gacgcaggtc
    15121 ggccttgtga ggtgacacaa agaaaaattg aattaactgt atgatttaaa agattatcgg
    15181 gagagttatc tcccgatttg acaggaagga tttacagaat gtgacctaag gtctggcgta
    15241 aatgtgcacc ggaaccgaga agacccggat tgtcatggac gatgagatat accggaatat
    15301 catggacata ttccttaaag cgccctttat cttcaaatgc ggcgcggaaa ccagaggctt
    15361 tgaagaactc aaggaagcgc ggcacgatac cacccgcaat aaacacgccg ccaaatgtcc
    15421 cgagattgag cgccagattg ccgccaaaac ggcccataat gacgcaaaac agcgacaacg
    15481 cgcggcggca atcggtgcag ctgtcagcca gcgcgcgttc ggtaatatct tttggcttga
    15541 gattttctgg caggcggttg tcggctttaa caattgcgcg atacaaattc accagcccag
    15601 ggccagaaag cacgcgctct gccgaaacat gaccaatttc tgcacgcagt atttcgagga
    15661 taatgccctc ttcttcacta ttcggcgcaa aatcaacgtg accgccttcg cctggcaagc
    15721 ttacccaacg cttatcgaca tggaccagat gcgcaacccc tagccccgtt ccggcaccgt
    15781 aaaccgcaat aggcttacct tctaccggtt ctgcgccacc aaactgaatc agatgctctt
    15841 ttttcagcat cgggatcgcc atcgatacag cagtaaaatc gttaataatt tccagatggc
    15901 taaaaccgag attctttttc atttcggcaa ttgagaacgc ccaggtatgg ttggtcattg
    15961 ccacccagtc accggtaatt gggcaagcga tggcaataca gccgtctttc acctcgacct
    16021 tatgttcttc aagataaacg cgaatgaccg cttcgaggct ggggtaatca agccctgaat
    16081 aggtcttagc ctgcgagatt tcaccactgg caatatcaca cagagcaaga cgtgcgttgg
    16141 tgccgcccac atcaccgact aatgcatact ttgtcattct tcaactgctc cgctaaagtc
    16201 aaaataattc tttctcacac tgtaaatacc tgggggcata acaacaacgc cggaaaggca
    16261 ggctccctgt aaatatcgat ctgggtcaca caattacttt atcgtttcag caccaattgc
    16321 agcgatgcct ttttgcaagc tgggcaaact aagtatctga ccccgcataa ggaatagaac
    16381 atgctccatc cgcgagccag aaccatgttg ttattatcgc tccccgccgt ggcaattggg
    16441 attgcgtcca gtcttattct gattgtggtg atgaaaatcg cctcggtatt acagaatttg
    16501 ctctggctac gactgccggg aactctgggg atagcccagg attcaccttt ctggatcatc
    16561 gccatattaa cgctaacagg tattgcggtg gggttggtta tccgtttcag ccaggggcat
    16621 gctggacctg accccgcctg tgaaccgctg atcggcgcac cagttccgcc ctctgcgcta
    16681 ccaggactta tcgtagcatt aattctcggt cttgctggcg gcgtcagcct ggggccggaa
    16741 catccgatca tgaccgtcaa tatcgccctt gcggttgcga taggtgctcg tctgttaccg
    16801 cgcgtcaacc ggatggagtg gactatttta gcctctgctg gaactatcgg cgcgctgttt
    16861 ggcacacctg ttgcggcggc gttgatattt tcgcaaacct taaatggcag tagtgaagtc
    16921 ccgctatggg atcgtctctt tgcgccgtta atggcggcgg cggctggtgc gctaaccacc
    16981 ggattgtttt tccatcctca tttttcactg cccattgcgc attatgggca gatggagatg
    17041 accgatattc tcagcggtgc aattgtggcg gcgattgcca tcgcagcagg gatggttgcc
    17101 gtatggtgtc tgccacggtt gcacgcgatg atgcatcaga ttaaaaatcc ggtgctaatg
    17161 ctgggagtgg gcggatttat tctcggtatt ctgggggtta ttgctggacc agtttcgcta
    17221 tttaaagggc tggatgagat gcagcagatg gtggcaaatc aggctttcag caccagcgat
    17281 tactttttgc tggccgtgat taaacttgcc gctctcgtgg ttgctgccgc cagtggcttt
    17341 cgcggtgggc gaatcttccc ggcagtgttt gtcggggtgg cattagggtt gatgctgcat
    17401 gagcacgttc ccgccgttcc agcggcaata accgtttcct gcgctattct cggcatcgtg
    17461 ctggtggtaa cacgcgatgg ctggttaagt ctttttatgg cggcagtcgt tgtacccaat
    17521 accacattgc taccgctgct ctgtatcgtc atgcttccgg catggctgtt attagcaggt
    17581 aagccgatga tgatggtcaa tcgtccgaag caacagccac cccacgataa cgtttagcaa
    17641 aaaatgctct cctttatgat ttaagagtta tggcgatgat acggggcttt acctccccgt
    17701 aatattgcgt taacaggccg ctgacggctt cgatcgtgaa ggagaataac aatgttcagg
    17761 tcactgtttc tggcggccgc cctgatggca tttaccccgc ttgcggcaaa cgcaggtgaa
    17821 atcaccctac tgccatcaat caaattacaa attggcgatc gcgatcatta cggtaattac
    17881 tgggacggtg gtcactggcg cgaccgtgac tactggcatc gcaattatga atggcgtaag
    17941 aaccgctggt ggcgtcatga taatggctac caccgtggct gggataagcg taaagcctat
    18001 gagcgtggct atcgtgaagg ctggcgcgat cgtgatgatc atcgcggaaa aggccgcgga
    18061 catgggcatc gccattaaac acatttgcca atggagcaca atgcctgatg cgacgctagc
    18121 gcgtcttatc aggcctacaa accagctctt taacgcgtag ggcggataaa gcatttacgc
    18181 cgcatccgcc aatggtgcca aatgcgacgc tcattcaact acaatccaag tgccgttcct
    18241 accagtaacc agatattcag cgccacgacc agcaccacaa tcacccagcc tgtctgtttt
    18301 acgcgtttac tgttcaccag atcgcccatc aacttgctgt cactggtgaa aatcaacagt
    18361 ggaaccagcg ccagggcgat accaaaactt aacagcacct gactcataac cagaatccgt
    18421 gtcggatcta atcccatcag aatgacgata aacgacggca gcatggtgac tgtacgacgc
    18481 acccacagcg ggatatgaaa gcgaatgaag ccctgcatca ctacctgccc cgccagcgtc
    18541 cccaccaccg ttgaagacag tccggcagca accaggctta atccaaagac cgttgccgca
    18601 gcatggctta acagcggttg cagcgtcaga taagcctcat caagatcggc aacaccagta
    18661 tgaccggaaa agtggaacgc cgccgcagct gtagccatca tcgccagatt gacaaaaccg
    18721 gcaatcgtca tggcgatagc cacatcccat ttggtggcgg aataacgttg ttgacgcgaa
    18781 ccgccatgta aatgctgagt gagcgaagag tgcaaataaa tcacatgcgg cataatcgtc
    18841 gcccccaaca cacctgccgc caggaagact gcctccgagg tgggtaaact cgggattacc
    18901 attcctttac ccagttgcgc caggttaggc tgggagaaaa tcaactcgac aatgtaagcc
    18961 gcagcaacaa acagcagtaa cccgccaatt actttctcca gcggtttttg ccctcgacgt
    19021 tgcagcatta aaatcaggaa agtcgcgatc cccgtcagca ccgcgccctg caacagcgaa
    19081 acacccagaa tgagtttaaa accgatcgcc gcaccaataa attctgccag gtcggttgcc
    19141 atcgcaatga tttctgcctg aacccaatag aaccacacta cgggacgcgg atagtgatcg
    19201 cgaatctgct ccgccaggtt tttaccggtg gcaatcccca gtttggcaga cagtatctga
    19261 atcagcatcg ccatcaggtt ggcccaaacg acaacccaca gtagctgata gccgaagctg
    19321 gccccggcct gaatattggt cgcaaagtta ccaggatcga tataaccaat cgccgcaatg
    19381 aacgcaggtc ccattaatgc gagcctcatc ttgcgcgccg cccgtccgct gctactctca
    19441 acgcgatagt tagtcatctt gtgcctctaa aacatagcct ttgctatgtt tcatgctatg
    19501 tcaaacgaga atgattatca aattcattta agtggattgt gatgatttct ttgatagacc
    19561 agaattatga cgacgaaaag attgatgact tgaatgttgt gattatgttt aatgttagca
    19621 catttacata actttcagct tccatacaca acatagcaga aatgtatgac agctcactat
    19681 ttttgaagct tgtcacagga cgtcattata gtgtgtgtca gatctcgttt tccttaacca
    19741 tgttacatag aatgtgcacg gaaatttaac ctgcctcata tttggagcaa atatggaccg
    19801 cgtccttcat tttgtactgg cacttgccgt tgttgcgatt ctcgcactgc tggtaagcag
    19861 cgaccgcaaa aaaattcgta tccgttatgt tattcaactg cttgttatcg aagtgttact
    19921 ggcgtggttc ttcctgaact ccgacgttgg tttgggcttc gtgaaaggct tctccgaaat
    19981 gtttgagaaa ctgctcggat ttgccaacga agggactaac ttcgtctttg gtagcatgaa
    20041 tgatcaaggc ctggcattct tcttcctgaa agtgctgtgc ccaatcgtct ttatctctgc
    20101 gctgatcggt attctccagc acattcgcgt gctgccagtg attatccgcg caattggttt
    20161 cctgctctcc aaagtcaacg gtatgggcaa actggaatcc tttaacgccg tcagctctct
    20221 gattctgggt cagtctgaaa actttattgc ctataaagat atcctcggca aaatctcccg
    20281 caatcgtatg tacaccatgg cagccacggc gatgtccacc gtgtcgatgt ccatcgttgg
    20341 tgcatacatg accatgctgg agccgaaata cgtcgttgcg gcgctggtac tgaacatgtt
    20401 cagcaccttt atcgtgctgt cgctgatcaa cccttaccgt gttgatgcca gtgaagaaaa
    20461 tattcagatg tccaacctgc acgaaggtca gagcttcttc gaaatgctgg gtgaatacat
    20521 tctggcaggt ttcaaagttg ccattatcgt tgccgcaatg ctgatcggct ttatcgccct
    20581 gatcgccgcg ctgaacgcac tgtttgccac cgtgactggc tggtttggct acagcatctc
    20641 cttccagggc atcctgggct acatcttcta tccgattgca tgggtgatgg gtgttccttc
    20701 cagtgaagca ctgcaagtgg gcagtatcat ggcgaccaaa ctggtttcca acgagttcgt
    20761 tgcgatgatg gatctgcaga aaattgcttc cacgctctct ccgcgtgctg aaggcatcat
    20821 ctctgtgttc ctggtttcct tcgctaactt ctcatcaatc gggattatcg caggtgcagt
    20881 taaaggcctg aatgaagagc aaggtaacgt ggtttctcgc ttcggtctga aactggttta
    20941 cggctctacc ctggtgagtg tgctgtctgc gtcaatcgca gcactggtgc tgtaagacca
    21001 tacataaaaa agccggggat aattccccgg ttttttacgc ctgttaatca gctaatggct
    21061 gcgggcgacc aatcaaatac ccttgcagat attgcacccc gagcttatgc aatagcgcct
    21121 gctgctgttg cgtctcgaca aactcagcga ccacactcaa tgacttcgct ttcgccagat
    21181 cggtaattga tctcacaatc atcgcatcca gcgtattcgt gacgatatct ttcacaaaga
    21241 cgccatcaat tttgatgata tcagcctgca aacgttttaa ccgttcgtag ttggcatagc
    21301 cggtgccaaa gtcatcaatc gcaatccgga aaccaaactt atgcagttgc tcgatgttgt
    21361 acatgctgct ttctgcgtta gaaaacgcct gctcctcggt gatctcaaga atgaccgcct
    21421 gcggggagat gtgataacgc ttaaacagac gaataatccg cccggcaata ttcttttgca
    21481 gcagcgtgag cggcattaaa ttgactgaaa agcgcgggcc ttttttgtcg caaggatgtg
    21541 ttgccagcca cttcaacagg gattccagca cttgcaaatc aaaacgcgcg ctaaggttaa
    21601 actgagcaat aaggggcaga aacttatccg gggtcataat gccgccgtca tatttcagtc
    21661 gcgcgaggat ctcatcataa ccttcaccct ctttgttgcg aattggctgg gcgtagagca
    21721 gcaaatcacc ctgatctaac gccgtacgaa tggtattcag caatagcacc tgtttagtgg
    21781 tctgcccgga aaccatctcc tctctgctat ccagcgccag cacatggtga tgtgcgcagg
    21841 attgctccgc cagccagctt aactgcccca acaagggttg cagggtttcc tgatttccat
    21901 caaaacgccc ccaggcagca ccatagccca tatccagccc ggtattgttc cagtgaattt
    21961 gccgactatt caggatgtta accatatgct ggagtcgccc ttccgtttcc ggcccgctca
    22021 gcactaacag cagttcacta cccggcaatt gatacaactt ttcgttttcc tgcatcaacg
    22081 gcagcagcgt acggtaaatt gagcggatac agtgaacgcg catcattaag ccgtaatgac
    22141 gactcataaa ctcaagatta tcaatgcgca ggcaacaaaa actcttgccc gcctcttgct
    22201 ccggcgcttg ctccaacgca cgaaagttgg gtaggagcgt taacggatcg gtcagcgcct
    22261 gcaaatgcca gcggcggtta agccattcac tacgatgata aatacgcacc atatagagca
    22321 ggcaaacact aaaggaaatc agtactgcga gaataaatgc cagcgaatat tcggttagta
    22381 ccccttgcaa aaagttctgg ttataattca gaaggcaaag cgttgaaaca gcccaggtga
    22441 gatttaaaaa cggatagcga agcttaccga caccgagggt aaagatgata aagaaaacag
    22501 gtaccaggta accggcaata aagtcatttt catacggtgt gcacatcaga agtagcagca
    22561 cgctaagagc tgccagccag cttaaggtaa atgcgcgttt ctctttgctc aacgacggag
    22621 cgatatccct gcgccacaat atctgtgcaa agtggggact tacaatcatg cgggtgagat
    22681 agtaaaaaag catgttgtaa atcagcactg cggtgaaaag gcttagcaaa tcaacgaccg
    22741 tgaaaatggc atccgcatcg ccgaaaaagg tggatatctt tagcgggaaa tcaaaaaagc
    22801 tccccacaag atacatgctg catttgatgc cgatcggcgt caccaaacca agccagaaaa
    22861 gacgttgcca gacatatcgg ctggtcaatc catatcgcca acgcgtcccc agctgccagc
    22921 gtaatattgc gcaggcacac aacacaacaa acgtctggct gccgagcatg accgcggtct
    22981 gtaaaaaaga gagatgaaag ttccacagat tggtgcaaaa catcccgcat aaaatgggaa
    23041 cgacaccgcg ccagccaaag ataaacaaga ttgacagcat tacgcacagt ggcatccacg
    23101 ccagaaagat ataactggaa tggataacag caagtggcga aataaaacgg gatagctgaa
    23161 taagtaccac ggtgagcgta aacgctagtg tgaatatctt gatatttttt atcaggttat
    23221 gctccacaaa catgagtaca ctactctcac tgatcggggt tttcaggcac acaaataata
    23281 agtttattcg catcgcgaag caaacagggg ccagcctgtt gccgattttc catccaatga
    23341 tgctttcacc aggcggcgct aacccggacg tagactgtat tacaaaagcg gcaaaaagca
    23401 gagacaaaaa aaccccgctt tacagcgagg gtttgaaatt tggtggagct aagcgggatc
    23461 gaaccgctga cctcttgcat gccatgcaag cgctctccca gctgagctat agccccacga
    23521 ggcgtttacg taccaaattt gctgggtgca aaatttggtg gagctaagcg ggatcgaacc
    23581 gctgacctct tgcatgccat gcaagcgctc tcccagctga gctatagccc cgtcacgtaa
    23641 agcttgtcga gttgacgggc ggcatcatat gaattccgcc cgaatgtgtc aacggcaaat
    23701 tgcaacctgt agtttcaatc gctgaaaaat caggcaaatg aacaattttg gaaaaccgct
    23761 cgcattcagt agttattcat gtcacggttt cctgtaaagt ggtgttataa aatgaactac
    23821 taatagaccc acatacattc agggaattgt tatgttcaag gagaggatga cgccagatga
    23881 acttgccaga ctgaccggct atagccgcca gaccattaat aaatgggtac gcaaggaagg
    23941 ctggacaacg tcaccaaaac caggcgtcca gggtggcaaa gctcgactgg ttcacgtcaa
    24001 tgaacaggtt cgtgaatata ttcgcaatgc tgaacgtccg gaaagtcagg gagaagcgcc
    24061 agccctttct ggtgatgcgc cgcttgaagt attgctggtg acactggcga aagagatgac
    24121 gccagttgaa caaaaacagt ttacatcctt gcttctgcgg gaagggatta tcggattgtt
    24181 acaacgctta gggattcgcg atagcaaata atatgaaaag attacgcaat aaaatgacca
    24241 ccgaagaact ggctgaatgc ctcggtgtgg ctaaacaaac tgttaaccgt tggatcagag
    24301 aaaaaggctg gaaaacggaa aaatttcccg gcgtgaaagg aggtcgtgcc agacttattc
    24361 tggtcgatac gcaagtttgc gagtttattc agaacacgcc agccttccat aacacgccga
    24421 tgcttctgga agccgaagaa ccccttgccg aatacgcacc ggggattcgc actcctgctt
    24481 atcggcaaat catcagcgca atagacaaca tgactcacag tgagcaggaa aaagttgcgc
    24541 aatttttgtc acgcgaagga attcgtaatt tccttgctcg tctcgatatt gacgaatcag
    24601 cataaataaa aaaacggcag gatattatct cctgccgttt atctttttat acgctaatta
    24661 ctgctggttt tcgcgttcag caataaaggc cagcgctttg ttgatacgct caatgctacg
    24721 agtcttaccg atcgcgtgaa cggtaacatc cagcgctgga gactgccccg caccggttac
    24781 ggcgacacgc agcggcatac caactttacc catacccact tccagctcat ccgccgtcgc
    24841 ctgaatagcg tgatgaacgt tttcagcggt ccagtcagta atcgcagtca gtttgtcacg
    24901 aaccacttcc agcggctgac gcgctaccgg acgcagatgt tttttcgcgg cgtcggcatc
    24961 gaactcagca aaatcttcgt agaaataacg gcagctctgt gccatctctt tcagcgtctt
    25021 gcagcgttcg cccagcagtt tcaccagatc agccagctgc gggccgttac gggtatcgat
    25081 attttcctgc tcaatgtgcc actgtaagtg agtagcaaca tactccggcg gcagcgcgtt
    25141 aatgtagtga tggttcagcc acagcagctt gtcggtgttg aacgcactgg cagatttgct
    25201 gacggcattc agagtgaagt atttgatcat ctcttcacga gtgaagattt cctgatcgcc
    25261 gtgggaccag cccagacgca ccagatagtt cagcagtgct tctggcagat aaccatcatc
    25321 acgatactgc attacgctga ccgccccgtg acgtttggac agttttttac cgtcatcgcc
    25381 gttgatcata gaaacgtgcg cgtaaaccgg taccggcgct ttcagggctt taagaatgtt
    25441 gatctggcgc ggcgtgttgt tgatatggtc ttcgccacgg ataacatggg tgatttccat
    25501 atcccagtca tcaacaacca cacagaagtt ataggttggg gaaccatcgg tacgacggat
    25561 aatcagatca tccagctcct ggttgctgaa ctcaatcggg ccacggatct gatcgtcaaa
    25621 aacaacagaa ccttcctgcg ggttagcaaa acgtacaacg cacggttcat catcagcatg
    25681 atgctcatgg ctgtggcggc agcgaccgtc ataacgcggc ttctcacctt tcgccatttg
    25741 ctcttcgcgc agcgcttcca ggcgctcttt agagcaatag catttataag ctgtgccctc
    25801 ttccagcatc tgatcgatca ccgcgttgta gcgatcaaaa cgtttggtct ggtagtacgg
    25861 accttcatcc cactccaggc tcagccagtt catgccatcc ataatggctt cgatagcttc
    25921 cggcgtggaa cgctcaagat cggtgtcttc aatacgcagc acgaactcac cgccgtggtt
    25981 acgtgcaaaa agccaggagt aaagagcagt acgcgcgccg ccaacgtgca gatagcctgt
    26041 tgggcttggc gcgaagcgag ttttgatttt catgaaatgg ccttacgttt agaaagatgc
    26101 cgacaaccgg caaatcctgg aaaaattgag tgggcgatat tctatcactc ccgcctgatt
    26161 cctcaatgta gttcgggttg caaccttacg cattattgtt ttcgttgaca aattgcgcaa
    26221 cacggtctgt tttgcgatca tcttgcttaa atttacgacg aacgaacaat ttctttagaa
    26281 aatgcgttga ctcattttga actctcccta taatgcgact ccacacagcg ggggtgatta
    26341 gctcagctgg gagagcacct cccttacaag gagggggtcg gcggttcgat cccgtcatca
    26401 cccaccaact ac
//
LOCUS       DADXDL010000065        26125 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.065, whole genome shotgun sequence.
ACCESSION   DADXDL010000065 DADXDL010000000
VERSION     DADXDL010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 26125)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26125)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26125
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.065"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            188..382
                     /gene="bfd"
                     /locus_tag="IRB70_003168"
     CDS             188..382
                     /gene="bfd"
                     /locus_tag="IRB70_003168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin-associated ferredoxin"
                     /protein_id="HBC0633046.1"
                     /translation="MYVCLCNGVSDKKIRQAVRQFHPQSFQQLRKFIPVGNQCGKCIR
                     AAREVMQDELMQMPEFKEIA"
     gene            455..931
                     /gene="bfr"
                     /locus_tag="IRB70_003169"
     CDS             455..931
                     /gene="bfr"
                     /locus_tag="IRB70_003169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterioferritin"
                     /protein_id="HBC0633047.1"
                     /translation="MKGDVKIINYLNKLLGNELVAINQYFLHARMFKNWGLMRLNDVE
                     YHESIDEMKHADKYIERILFLEGIPNLQDLGKLGIGEDVEEMLQSDLRLELEGAKDLR
                     EAIAYADSVHDYVSRDMMIEILADEEGHIDWLETELDLIGKIGLQNYLQSQIKVKD"
     gene            complement(928..1395)
                     /locus_tag="IRB70_003170"
     CDS             complement(928..1395)
                     /locus_tag="IRB70_003170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBC0633048.1"
                     /translation="MDATLPFLILYACLSALLFFWDAKHGLLPDRFTCPLLWSGLLFY
                     QVCNPDGLADALWGAIIGYGTFAVIYWGYRILRHKEGLGYGDVKFLAALGAWHTWTFL
                     PRLVFLAASFACGAVVIGLLMRGKESLKNPLPFGPFLATAGFVVGWDSLLAGR"
     gene            1774..2085
                     /gene="rpsJ"
                     /locus_tag="IRB70_003171"
     CDS             1774..2085
                     /gene="rpsJ"
                     /locus_tag="IRB70_003171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014268624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBC0633049.1"
                     /translation="MQNQRIRIRLKAFDHRLIDQATAEIVETAKRTGAQVRGPIPLPT
                     RKERFTVLISPHVNKDARDQYEIRTHLRLVDIVEPTEKTVDALMRLDLAAGVDVQISL
                     G"
     gene            2118..2747
                     /gene="rplC"
                     /locus_tag="IRB70_003172"
     CDS             2118..2747
                     /gene="rplC"
                     /locus_tag="IRB70_003172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000579825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBC0633050.1"
                     /translation="MIGLVGKKVGMTRIFTEDGVSIPVTVIEVEANRVTQVKDLANDG
                     YRAIQVTTGAKKANRVTKPEAGHFAKAGVEAGRGLWEFRLAEGEEFTVGQSISVELFA
                     DVKKVDVTGTSKGKGFAGTVKRWNFRTQDATHGNSLSHRVPGSIGQNQTPGKVFKGKK
                     MAGQMGNERVTVQSLDVVRVDAERNLLLVKGAVPGATGSDLIVKPAVKA"
     gene            2758..3363
                     /gene="rplD"
                     /locus_tag="IRB70_003173"
     CDS             2758..3363
                     /gene="rplD"
                     /locus_tag="IRB70_003173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010304939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBC0633051.1"
                     /translation="MELVLKDAQSALTVSETTFGRDFNEALVHQVVVAYAAGARQGTR
                     AQKTRAEVTGSGKKPWRQKGTGRARSGSIKSPIWRSGGVTFAARPQDHSQKVNKKMYR
                     GALKSILSELVRQDRLIVVEKFSVEAPKTKLLAQKLKDMALEDVLIITGELDENLFLA
                     ARNLHKVDVRDATGIDPVSLIAFDKVVMTADAVKQVEEMLA"
     gene            3360..3662
                     /gene="rplW"
                     /locus_tag="IRB70_003174"
     CDS             3360..3662
                     /gene="rplW"
                     /locus_tag="IRB70_003174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007891652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBC0633052.1"
                     /translation="MIREERLLKVLRAPHVSEKASTAMEKSNTIVLKVAKDATKAEIK
                     AAVQKLFEVEVEVVNTLVVKGKVKRHGQRIGRRSDWKKAYVTLKEGQNLDFVGGAE"
     gene            3680..4501
                     /gene="rplB"
                     /locus_tag="IRB70_003175"
     CDS             3680..4501
                     /gene="rplB"
                     /locus_tag="IRB70_003175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001738551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBC0633053.1"
                     /translation="MAVVKCKPTSPGRRHVVKVVNPELHKGKPFAPLLEKNSKSGGRN
                     NNGRITTRHIGGGHKQAYRIVDFKRNKDGIPAVVERLEYDPNRSANIALVLYKDGERR
                     YILAPKGLKAGDQIQSGVDAAIKPGNTLPMRNIPVGSTVHNVEMKPGKGGQLARSAGT
                     YVQIVARDGAYVTLRLRSGEMRKVEADCRATLGEVGNAEHMLRVLGKAGAARWRGVRP
                     TVRGTAMNPVDHPHGGGEGRNFGKHPVTPWGVQTKGKKTRSNKRTDKFIVRRRSK"
     gene            4518..4796
                     /gene="rpsS"
                     /locus_tag="IRB70_003176"
     CDS             4518..4796
                     /gene="rpsS"
                     /locus_tag="IRB70_003176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBC0633054.1"
                     /translation="MPRSLKKGPFIDLHLLKKVEKAVESGDKKPLRTWSRRSTIFPNM
                     IGLTIAVHNGRQHVPVFVTDEMVGHKLGEFAPTRTYRGHAADKKAKKK"
     gene            4811..5143
                     /gene="rplV"
                     /locus_tag="IRB70_003177"
     CDS             4811..5143
                     /gene="rplV"
                     /locus_tag="IRB70_003177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000447526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBC0633055.1"
                     /translation="METIAKHRHARSSAQKVRLVADLIRGKKVSQALDILTYTNKKAA
                     VLVKKVLESAIANAEHNDGADIDDLKVTKIFVDEGPSMKRIMPRAKGRADRILKRTSH
                     ITVVVSDR"
     gene            5161..5862
                     /gene="rpsC"
                     /locus_tag="IRB70_003178"
     CDS             5161..5862
                     /gene="rpsC"
                     /locus_tag="IRB70_003178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001742302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBC0633056.1"
                     /translation="MGQKVHPNGIRLGIVKPWNSTWFANTKEFADNLDSDFKVRQYLT
                     KELAKASVSRIVIERPAKSIRVTIHTARPGIVIGKKGEDVEKLRKVVADIAGVPAQIN
                     IAEVRKPELDAKLVADSITSQLERRVMFRRAMKRAVQNAMRLGAKGIKVEVSGRLGGA
                     EIARTEWYREGRVPLHTLRADIDYNTSEAHTTYGVIGVKVWIFKGEILGGMAAVEQPE
                     KPAAQPKKQQRKGRK"
     gene            5875..6285
                     /gene="rplP"
                     /locus_tag="IRB70_003179"
     CDS             5875..6285
                     /gene="rplP"
                     /locus_tag="IRB70_003179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017805229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBC0633057.1"
                     /translation="MLQPKRTKFRKMHKGRNRGLAQGTDVSFGSFGLKAVGRGRLTAR
                     QIEAARRAMTRAVKRQGKIWIRVFPDKPITEKPLAVRMGKGKGNVEYWVALIQPGKVL
                     YEMDGVPEELAREAFKLAAAKLPIKTTFVTKTVM"
     gene            6285..6476
                     /gene="rpmC"
                     /locus_tag="IRB70_003180"
     CDS             6285..6476
                     /gene="rpmC"
                     /locus_tag="IRB70_003180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000644743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBC0633058.1"
                     /translation="MKAKELREKSVEELNTELLNLLREQFNLRMQAASGQLQQSHLLK
                     QVRRDVARVKTLLNEKAGA"
     gene            6476..6730
                     /gene="rpsQ"
                     /locus_tag="IRB70_003181"
     CDS             6476..6730
                     /gene="rpsQ"
                     /locus_tag="IRB70_003181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006817275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBC0633059.1"
                     /translation="MTDKIRTLQGRVVSDKMEKSIVVAIERFVKHPIYGKFIKRTTKL
                     HVHDENNECGIGDVVEIRECRPLSKTKSWTLVRVVEKAVL"
     gene            6895..7266
                     /gene="rplN"
                     /locus_tag="IRB70_003182"
     CDS             6895..7266
                     /gene="rplN"
                     /locus_tag="IRB70_003182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015817037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBC0633060.1"
                     /translation="MIQEQTMLNVADNSGARRVMCIKVLGGSHRRYAGVGDIIKITIK
                     EAIPRGKVKKGDVLKAVVVRTKKGVRRPDGSVIRFDGNACVLLNNNSEQPIGTRIFGP
                     VTRELRSEKFMKIISLAPEVL"
     gene            7277..7591
                     /gene="rplX"
                     /locus_tag="IRB70_003183"
     CDS             7277..7591
                     /gene="rplX"
                     /locus_tag="IRB70_003183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBC0633061.1"
                     /translation="MAAKIRRDDEVIVLTGKDKGKRGKVKNVLSSGKVIVEGINLVKK
                     HQKPVPALNQPGGIVEKEAAIQVSNVAIFNAATGKADRVGFRFEDGKKVRFFKSNSET
                     IK"
     gene            7606..8145
                     /gene="rplE"
                     /locus_tag="IRB70_003184"
     CDS             7606..8145
                     /gene="rplE"
                     /locus_tag="IRB70_003184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001096198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBC0633062.1"
                     /translation="MAKLHDYYKDEVVKKLMTEFNYNSVMQVPRVEKITLNMGVGEAI
                     ADKKLLDNAAADLAAISGQKPLITKARKSVAGFKIRQGYPIGCKVTLRGERMWEFFER
                     LITIAVPRIRDFRGLSAKSFDGRGNYSMGVREQIIFPEIDYDKVDRVRGLDITITTTA
                     KSDEEGRALLAAFDFPFRK"
     gene            8160..8465
                     /gene="rpsN"
                     /locus_tag="IRB70_003185"
     CDS             8160..8465
                     /gene="rpsN"
                     /locus_tag="IRB70_003185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005599304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBC0633063.1"
                     /translation="MAKQSMKAREVKRVALADKYFAKRAELKAIISDVNASDEDRWNA
                     VLKLQTLPRDSSPSRQRNRCRQTGRPHGFLRKFGLSRIKVREAAMRGEIPGLKKASW"
     gene            8499..8891
                     /gene="rpsH"
                     /locus_tag="IRB70_003186"
     CDS             8499..8891
                     /gene="rpsH"
                     /locus_tag="IRB70_003186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011148781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBC0633064.1"
                     /translation="MSMQDPIADMLTRIRNGQAANKAAVTMPSSKLKVAIANVLKEEG
                     FIEDFKVEGDTKPELELTLKYFQGKAVVESIQRVSRPGLRIYKRKDELPKVMAGLGIA
                     VVSTSKGVMTDRAARQAGLGGEIICYVA"
     gene            8904..9437
                     /gene="rplF"
                     /locus_tag="IRB70_003187"
     CDS             8904..9437
                     /gene="rplF"
                     /locus_tag="IRB70_003187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003031129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBC0633065.1"
                     /translation="MSRVAKAPVVVPAGVDVKINGQVITIKGKNGELTRTLNDAVEVK
                     HADNTLTFGPRDGYVDGWAQAGTARALLNSMVIGVTEGFTKKLQLVGVGYRAAVKGNV
                     INLSLGFSHPVDHQLPAGITAECPTQTEIVLKGADKQVIGQVAADLRAYRRPEPYKGK
                     GVRYADEVVRTKEAKKK"
     gene            9447..9800
                     /gene="rplR"
                     /locus_tag="IRB70_003188"
     CDS             9447..9800
                     /gene="rplR"
                     /locus_tag="IRB70_003188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBC0633066.1"
                     /translation="MDKKSARIRRATRARRKLQELGATRLVVHRTPRHIYAQVIAPNG
                     SEVLVAASTVEKAIAEQLKYTGNKDAAAAVGKAVAERALEKGIKDVSFDRSGFQYHGR
                     VQALADAAREAGLQF"
     gene            9815..10318
                     /gene="rpsE"
                     /locus_tag="IRB70_003189"
     CDS             9815..10318
                     /gene="rpsE"
                     /locus_tag="IRB70_003189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004106339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBC0633067.1"
                     /translation="MAHIEKQAGELQEKLIAVNRVSKTVKGGRIFSFTALTVVGDGNG
                     RVGFGYGKAREVPAAIQKAMEKARRNMINVALNNGTLQHPVKGVHTGSRVFMQPASEG
                     TGIIAGGAMRAVLEVAGVHNVLAKAYGSTNPINVVRATIDGLENMNSPEMVAAKRGKS
                     VEEILGK"
     gene            10322..10501
                     /gene="rpmD"
                     /locus_tag="IRB70_003190"
     CDS             10322..10501
                     /gene="rpmD"
                     /locus_tag="IRB70_003190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012147215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBC0633068.1"
                     /translation="MAKTIKITQTRSAIGRLPKHKATLLGLGLRRIGHTVEREDTPAI
                     RGMINAVSFMVKVEE"
     gene            10505..10939
                     /gene="rplO"
                     /locus_tag="IRB70_003191"
     CDS             10505..10939
                     /gene="rplO"
                     /locus_tag="IRB70_003191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011095501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBC0633069.1"
                     /translation="MRLNTLSPAEGSKKAGKRLGRGIGSGLGKTGGRGHKGQKSRSGG
                     GVRRGFEGGQMPLYRRLPKFGFTSRKAAITAEVRLSDLAKVEGGVVDLNTLKAANIIG
                     IQIEFAKVILAGEVTTPVTVRGLRVTKGARAAIEAAGGKIEE"
     gene            10947..12278
                     /gene="secY"
                     /locus_tag="IRB70_003192"
     CDS             10947..12278
                     /gene="secY"
                     /locus_tag="IRB70_003192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004868351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBC0633070.1"
                     /translation="MAKQPGLDFQSAKGGLGELKRRLLFVIGALIVFRIGSFIPIPGI
                     DAAVLAKLLEQQRGTIIEMFNMFSGGALSRASIFALGIMPYISASIIIQLLTVVHPTL
                     AEIKKEGESGRRKISQYTRYGTLVLAIFQSIGIATGLPNMPGMQGLVINPGFAFYFTA
                     VVSLVTGTMFLMWLGEQITERGIGNGISIIIFAGIVAGLPPAIAHTIEQARQGDLHFL
                     VLLLVAVLVFAVTFFVVFVERGQRRIVVNYAKRQQGRRVYAAQSTHLPLKVNMAGVIP
                     AIFASSIILFPATIASWFGGGTGWNWLTTISLYLQPGQPLYVLLYASAIIFFCFFYTA
                     LVFNPRETADNLKKSGAFVPGIRPGEQTAKYIDKVMTRLTLVGALYITFICLIPEFMR
                     DAMKVPFYFGGTSLLIVVVVIMDFMAQVQTLMMSSQYESALKKANLKGYGR"
     gene            12310..12426
                     /gene="rpmJ"
                     /locus_tag="IRB70_003193"
     CDS             12310..12426
                     /gene="rpmJ"
                     /locus_tag="IRB70_003193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020322760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBC0633071.1"
                     /translation="MKVRASVKKLCRNCKIVKRDGVIRVICSAEPKHKQRQG"
     gene            12573..12929
                     /gene="rpsM"
                     /locus_tag="IRB70_003194"
     CDS             12573..12929
                     /gene="rpsM"
                     /locus_tag="IRB70_003194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019935869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBC0633072.1"
                     /translation="MARIAGINIPDHKHAVIALTSIYGVGKTRSKAILAAAGIAEDVK
                     ISELSEGQIDTLRDEVAKFVVEGDLRREISMSIKRLMDLGCYRGLRHRRGLPVRGQRT
                     KTNARTRKGPRKPIKK"
     gene            12946..13335
                     /gene="rpsK"
                     /locus_tag="IRB70_003195"
     CDS             12946..13335
                     /gene="rpsK"
                     /locus_tag="IRB70_003195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001029758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBC0633073.1"
                     /translation="MAKAPIRARKRVRKQVSDGVAHIHASFNNTIVTITDRQGNALGW
                     ATAGGSGFRGSRKSTPFAAQVAAERCADAVKEYGIKNLEVMVKGPGPGRESTIRALNA
                     AGFRITNITDVTPIPHNGCRPPKKRRV"
     gene            13369..13989
                     /gene="rpsD"
                     /locus_tag="IRB70_003196"
     CDS             13369..13989
                     /gene="rpsD"
                     /locus_tag="IRB70_003196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004410410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBC0633074.1"
                     /translation="MARYLGPKLKLSRREGTDLFLKSGVRAIDTKCKIEQAPGQHGAR
                     KPRLSDYGVQLREKQKVRRIYGVLERQFRNYYKEAARLKGNTGENLLALLEGRLDNVV
                     YRMGFGATRAEARQLVSHKAIMVNGRVVNIASYQVSPNDVVSIREKAKKQSRVKAALE
                     LAEQREKPTWLEVDAGKMEGTFKRKPERSDLSADINEHLIVELYSK"
     gene            14015..15004
                     /gene="rpoA"
                     /locus_tag="IRB70_003197"
     CDS             14015..15004
                     /gene="rpoA"
                     /locus_tag="IRB70_003197"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005970247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBC0633075.1"
                     /translation="MQGSVTEFLKPRLVDIEQVSSTHAKVTLEPLERGFGHTLGNALR
                     RILLSSMPGCAVTEVEIDGVLHEYSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTL
                     NKSGIGPVTAADITHDGDVEIVKPQHVICHLTDENASISMRIKVQRGRGYVPASTRIH
                     SEEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETNGTIDPEEAIR
                     RAATILAEQLEAFVDLRDVRQPEVKEEKPEFDPILLRPVDDLELTVRSANCLKAEAIH
                     YIGDLVQRTEVELLKTPNLGKKSLTEIKDVLASRGLSLGMRLENWPPASIADE"
     gene            15045..15428
                     /gene="rplQ"
                     /locus_tag="IRB70_003198"
     CDS             15045..15428
                     /gene="rplQ"
                     /locus_tag="IRB70_003198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBC0633076.1"
                     /translation="MRHRKSGRQLNRNSSHRQAMFRNMAGSLVRHEIIKTTLPKAKEL
                     RRVVEPLITLAKTDSVANRRLAFARTRDNEIVAKLFNELGPRFASRAGGYTRILKCGF
                     RAGDNAPMAYIELVDRSEKAEAAAE"
     gene            15535..15903
                     /locus_tag="IRB70_003199"
     CDS             15535..15903
                     /locus_tag="IRB70_003199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1992 domain-containing protein"
                     /protein_id="HBC0633077.1"
                     /translation="MWLLDQWAERHITEAQAKGEFDNLPGIGEPLILDDDSHVPPELR
                     AGYRLLKNAGCLPPELEQRKEAIQLLDILKGIRQDDQQYQEVSRQLSLLELKLRQAGL
                     STEFLRGEYADKLLNKINDN"
     gene            15914..16339
                     /gene="zntR"
                     /locus_tag="IRB70_003200"
     CDS             15914..16339
                     /gene="zntR"
                     /locus_tag="IRB70_003200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn(2+)-responsive transcriptional regulator"
                     /protein_id="HBC0633078.1"
                     /translation="MYRIGELAKLAEVTPDTIRYYEKQQMMEHEVRTEGGFRLYTESD
                     LQRLKFIRHARQLGFSLESIRELLSIRIDPEHHTCQESKGIVQERLQEVEARIAELQS
                     MQRSLQRLNDACCGTAHSSVYCSILEALEQGASGVKSGC"
     gene            16395..16613
                     /gene="arfA"
                     /locus_tag="IRB70_003201"
     CDS             16395..16613
                     /gene="arfA"
                     /locus_tag="IRB70_003201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alternative ribosome-rescue factor ArfA"
                     /protein_id="HBC0633079.1"
                     /translation="MSRYQHTKGQIKDNAIEALLHDPLFRQRVEKNKKGKGSYMRKGK
                     HGNRGNWEASGKKVNHFFTTGLLLSGAC"
     gene            complement(16610..17020)
                     /gene="mscL"
                     /locus_tag="IRB70_003202"
     CDS             complement(16610..17020)
                     /gene="mscL"
                     /locus_tag="IRB70_003202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large-conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBC0633080.1"
                     /translation="MSIIKEFREFAMRGNVVDLAVGVIIGAAFGKIVSSLVADIIMPP
                     LGLLIGGIDFKQFAVTLRDAQGDIPAVVMHYGVFIQNVFDFLIVAFAIFMAIKLINKL
                     NRKKEEPAAAPAPTKEEVLLTEIRDLLKEQNNRS"
     gene            complement(17150..18526)
                     /gene="trkA"
                     /locus_tag="IRB70_003203"
     CDS             complement(17150..18526)
                     /gene="trkA"
                     /locus_tag="IRB70_003203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004125888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Trk system potassium transporter TrkA"
                     /protein_id="HBC0633081.1"
                     /translation="MKIIILGAGQVGGTLAENLVGENNDITVVDTNGERLRTLQDKFD
                     LRVVQGHGSHPRVLREAGADDADMLVAVTSSDETNMVACQVAYSLFNTPNRIARIRSP
                     DYVRDADKLFHSDAVPIDHLIAPEQLVIDNIYRLIEYPGALQVVNFAEGKVSLAVVKA
                     YYGGPLIGNALSTMREHMPHIDTRVAAIFRHDRPIRPQGSTIVEAGDEVFFIAASQHI
                     RAVMSELQRLEKPYKRIMLVGGGNIGAGLARRLEKDYSVKLIERNQQRAAELAEKLQN
                     TIVFFGDASDQELLAEEHIDQVDLFIAVTNDDEANIMSAMLAKRMGAKKVMVLIQRRA
                     YVDLVQGSVIDIAISPQQATISALLSHVRKADIVGVSSLRRGVAEAIEAVAHGDESTS
                     RVVGRVIDEIKLPPGTIIGAVVRGNDVMIANDNLRIEQGDHVIMFLTDKKFITDVERL
                     FQPSPFFL"
     gene            complement(18548..19837)
                     /gene="rsmB"
                     /locus_tag="IRB70_003204"
     CDS             complement(18548..19837)
                     /gene="rsmB"
                     /locus_tag="IRB70_003204"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBC0633082.1"
                     /translation="MKKQRNLRSMAAQAVEQVVEQGQSLSNILPPLQQKVSDKDKALL
                     QELCFGVLRTLSQLDWLINKLMARPMTGKQRTVHYLIMVGLYQLLYTRIPPHAALAET
                     VEGAVAIKRPQLKGLINGVLRQFQRQQDELLAEFNASDARYLHPSWLLKRLQKAYPEQ
                     WQSIVEANNQRPPMWLRVNRTHHSRDSWLALLDEAGMKGFPHADYPDAVQLETPAPVH
                     ALPGFEEGWVTVQDASAQGCMTWLAPQNGEHILDLCAAPGGKTTHILEVAPEAQVLAV
                     DIDEQRLSRVYDNLKRLGMKATVKQGDGRYPSQWCGEQQFDRILLDAPCSATGVIRRH
                     PDIKWLRRDRDIPELAQLQSEILDAIWPHLKSGGTLVYATCSVLPEENSLQIKAFLQR
                     TADAELCETGTPEQPGKQNLPGAEEGDGFFYAKLIKK"
     gene            complement(19883..20830)
                     /gene="fmt"
                     /locus_tag="IRB70_003205"
     CDS             complement(19883..20830)
                     /gene="fmt"
                     /locus_tag="IRB70_003205"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBC0633083.1"
                     /translation="MSESLRIIFAGTPDFAARHLDALLSSGHNVVGVFTQPDRPAGRG
                     KKLMPSPVKVLAEEKGLPVFQPVSLRPQENQQLVADLQADVMVVVAYGLILPKAVLEM
                     PRLGCINVHGSLLPRWRGAAPIQRSLWAGDAETGVTIMQMDIGLDTGDMLYKLSCPIT
                     AEDTSGTLYDKLAELGPQGLITTLKQLADGTAKPEVQDETLVTYAEKLSKEEARIDWS
                     LSAAQLERCIRAFNPWPMSWLEIEGQPVKVWKASVIDTVTKSAPGTILEASKQGIQVA
                     TGDGILNLLSLQPAGKKAMSAQDLLNSRREWFVPGNRLA"
     gene            complement(20845..21354)
                     /gene="def"
                     /locus_tag="IRB70_003206"
     CDS             complement(20845..21354)
                     /gene="def"
                     /locus_tag="IRB70_003206"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBC0633084.1"
                     /translation="MSVLQVLHIPDERLRKVAKPVEEVNAEIQRIVDDMFETMYAEEG
                     IGLAATQVDIHQRIIVIDVSENRDERLVLINPELLEKSGETGIEEGCLSIPEQRALVP
                     RAEKVKIRALDRDGKPFELEAEGLLAICIQHEMDHLVGKLFMDYLSPLKQQRIRQKVE
                     KLDRLKARA"
     gene            21484..22608
                     /gene="dprA"
                     /locus_tag="IRB70_003207"
     CDS             21484..22608
                     /gene="dprA"
                     /locus_tag="IRB70_003207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBC0633085.1"
                     /translation="MVDTEIWLRLMSVSSLYGDDMVRIAHWLAKQSHIDAVVLQQTGL
                     TLRQAQRFLSFPRKSIESSLCWLEQPNHHLISADSEFYPPQLLATTDYPGTLFVEGEL
                     HALHSFQLAVVGSRAHSWYGERWGRLFCETLATRGVTITSGLARGIDGVAHKAALQVN
                     GVSIAVLGNGLNTIHPRRHAPLAASLLEQGGALVSEFPLDVPPLAYNFPRRNRIISGL
                     SKGVLVVEAALRSGSLVTARCALEQGREVFALPGPLGNPGSEGPHWLIKQGAILVTEP
                     EEILENLQFGLHWLPDAPENSFYSPDQEDVALPFPELLANVGDEVTPVDVVAERAGQP
                     VPEVVTQLLELELAGWIAAVPGGYVRLRRACHVRRTNVFV"
     gene            22580..23053
                     /locus_tag="IRB70_003208"
     CDS             22580..23053
                     /locus_tag="IRB70_003208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005134083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF494 domain-containing protein"
                     /protein_id="HBC0633086.1"
                     /translation="MFDVLMYLFETYIHTEAELRVDQDKLEQDLTDAGFDREDIYNAL
                     LWLEKLADYQEGLAEPMQLASDPLSMRIYTPEECERLDASCRGFLLFLEQIQVLNLET
                     REMVIERVLALDTAEFDLEDLKWVILMVLFNIPGCENAYQQMEELLFEVNEGMLH"
     gene            23082..23624
                     /locus_tag="IRB70_003209"
     CDS             23082..23624
                     /locus_tag="IRB70_003209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
                     /protein_id="HBC0633087.1"
                     /translation="MAKSALFTVRNNESCPKCGAELVIRSGKHGPFLGCSQYPACDYV
                     RPLKSSADGHIVKVLEGQICPACGANLVLRQGRFGMFVGCSNYPECEHTELIDKPDET
                     AITCPQCRTGHLVQRRSRYGKTFHSCDRYPECQFAINFKPIAGECPECHYPLLIEKKT
                     AQGVKHFCASKQCGKPVSAE"
     gene            23629..24201
                     /gene="tsaC"
                     /locus_tag="IRB70_003210"
     CDS             23629..24201
                     /gene="tsaC"
                     /locus_tag="IRB70_003210"
                     /EC_number="2.7.7.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonylcarbamoyladenylate synthase type 1
                     TsaC"
                     /protein_id="HBC0633088.1"
                     /translation="MNNNLQGDAIAAAIDVLNEERVIAYPTEAVFGVGCDPDSETAVM
                     RLLELKQRPVDKGLILIAANYEQLKPYIDDCMLTDAQRETIFSRWPGPVTFVFPAPAT
                     TPRWLTGRFDSLAVRVTDHPLVVALCQAYGKPLVSTSANLSGLPPCRTVDEVRAQFGA
                     AFPVVPGETGGRLNPSEIRDALTGELFRQG"
     gene            24206..25024
                     /gene="aroE"
                     /locus_tag="IRB70_003211"
     CDS             24206..25024
                     /gene="aroE"
                     /locus_tag="IRB70_003211"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBC0633089.1"
                     /translation="MENYAVFGNPIAHSKSPFIHQQFAQQLNIEHPYGRVLAPINDFI
                     NTLNAFFSAGGKGANVTVPFKEEAFARADELTERAALAGAVNTLKRLEDGRLLGDNTD
                     GVGLLSDLERLSFIRPGLRILLIGAGGASRGVLLPLLSLDCAVTITNRTVSRAEELAK
                     LFAHTGSIQALGMDELEGHEFDLIINATSSGISGDIPAIPASLIHSGMCCYDMFYQKG
                     KTPFLAWCELRGSKRNADGLGMLVAQAAHAFLLWHGVLPDIEPVIKQLQEELSA"
     gene            25021..25278
                     /locus_tag="IRB70_003212"
     CDS             25021..25278
                     /locus_tag="IRB70_003212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1488 domain-containing protein"
                     /protein_id="HBC0633090.1"
                     /translation="MNQAIQFPDREEWNESKKCVCFPALVNGMQLTCAITGESLANRF
                     AGDTPEQWLASFRQHRWDLEEEAENLIQEQSEDDQGWVWLP"
     gene            complement(25254..25808)
                     /locus_tag="IRB70_003213"
     CDS             complement(25254..25808)
                     /locus_tag="IRB70_003213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417738.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBC0633091.1"
                     /translation="MSDVLRPYRDLFPQIGQRVMIDDSSVVIGDVRLADDVGIWPLVV
                     IRGDVHYVQIGARTNIQDGSMLHVTHKSSYNPDGNPLTIGEDVTVGHKVMLHGCTIGN
                     RVLVGMASILLDGAIVEDDVMIGAGSLVPQNKRLKSGYLYLGSPVKQIRPLSDEEKAG
                     LRYSANNYVKWKDEYLDQGNQTQP"
BASE COUNT         6728 a         6188 c         6750 g         6459 t
ORIGIN      
        1 gctaattact cgttaattag ttttgaattg aaaagggcgc ttcggcgccc tttttgctgc
       61 ccgtaatttg agctcgaaat atttagtcgt aatttcactc gctgaactat ggcgcaaata
      121 aaattgtgct attgtaatca taaccattct catttacact ttgcgcagaa tttgaacggg
      181 agcaatcatg tacgtttgtt tgtgtaatgg tgtaagtgac aaaaaaattc gccaggcagt
      241 acgtcagttt catccgcaat ctttccaaca attgcgtaag tttattcctg tgggaaatca
      301 atgcggtaag tgcattcgcg ccgcgcgcga agtgatgcag gacgagttga tgcagatgcc
      361 agaatttaaa gagattgcct gaagcccacg cttatttttt gacatcccgc tagccccatc
      421 tacgctctaa tagtggaagc ggagggacta taaaatgaaa ggtgatgtta aaatcataaa
      481 ttatctcaat aaactattgg gaaatgagct tgtcgcaatc aatcagtatt ttctccatgc
      541 ccggatgttt aaaaactggg gcctgatgcg tctcaatgac gtcgaatacc atgaatctat
      601 cgatgagatg aaacacgctg ataaatatat cgagcgtatt ttgtttttag aaggaatccc
      661 caacttacag gatttaggca aactggggat tggtgaagat gtcgaggaga tgctgcaatc
      721 cgacctgcga ttagaactgg aaggcgctaa ggatctccgt gaggctatcg cgtatgccga
      781 cagcgttcat gactatgtta gccgtgatat gatgatcgag atccttgccg atgaagaagg
      841 tcatattgac tggctcgaaa ctgagctgga tctcatcggt aaaatcggtc tacaaaatta
      901 cctgcaatca caaataaaag ttaaagatta acggcctgcc agcaaactat cccagcctac
      961 aacgaaaccc gcagtcgcca gaaatggccc aaacggcagc gggtttttta atgactcttt
     1021 tcctctcatg agcagaccaa taactacggc tccgcaagcg aatgaggcag caaggaaaac
     1081 cagtcgtggc aagaaggtcc atgtatgcca ggcaccaagg gcggcgagaa acttcacatc
     1141 accatagcct aatccttctt tatgacgcag aatgcgatac ccccagtaaa tgacagcgaa
     1201 tgtgccgtaa ccaataatcg ccccccataa cgcatcggct aaaccgtcag gattacaaac
     1261 ttgatagaac aaaagacctg accagagtaa cgggcacgta aatctgtcag gtaacaagcc
     1321 atgctttgca tcccagaaaa aaagtagggc tgataaacaa gcgtacaaaa tcagaaaggg
     1381 aagggtagcg tccataaaac atcctctgta attggagtat caccatcgaa taactccgga
     1441 tgctcagcaa cagagaaatc gctgatttgt taacctggtt ccggtgaaaa acgctatctt
     1501 cacaacttta caaatttcgt ggaatacagc tcgcaatctg cgcgttgcga ttaatttcta
     1561 cccgatgctt gcgtcaggct cagatttgcg tataatgcgc gggcttgtcg tagttgacag
     1621 caggttcaat ctgaacctca gttagccgaa tttggctacc taacaatgct cccaatcggg
     1681 gagctacgta agaacggtta cactctccca tcaatcgtaa tgggtctgag gagtaatcat
     1741 tttcgtttat aaaataattg gagctctggt ctcatgcaga accaaagaat ccgtatccgc
     1801 ctgaaagcgt ttgatcatcg tctgatcgat caagcaaccg cggaaatcgt cgagactgcc
     1861 aagcgcactg gtgcgcaggt ccgtggtccg atcccgctgc cgacacgcaa agagcgcttc
     1921 actgttctga tctccccgca cgtcaacaaa gacgcgcgcg atcagtacga aatccgtact
     1981 cacttgcgtc tggttgacat cgttgagcca accgagaaaa ccgttgatgc tctgatgcgt
     2041 ctggatctgg ctgccggtgt agacgtgcag atcagcctgg gttaatcagg tcattgagcg
     2101 attgagaggt tgaaacaatg attggtttag tcggtaaaaa agtgggtatg acccgtatct
     2161 tcacagaaga cggcgtttct atcccagtaa ccgtaatcga agttgaagca aaccgcgtta
     2221 ctcaggttaa agacctggct aacgatggct accgtgctat tcaggtaacc accggtgcta
     2281 aaaaagctaa ccgtgtgacc aagcctgaag ctggccactt cgctaaagct ggcgtagaag
     2341 ctggccgtgg tctgtgggaa ttccgcctgg ctgaaggcga agagttcact gtaggtcaga
     2401 gcattagcgt tgaactgttt gctgacgtta aaaaagttga cgtaactggc acctctaaag
     2461 gtaaaggttt cgcaggtacc gttaagcgct ggaacttccg tacccaggac gctactcacg
     2521 gtaactcctt gtctcaccgc gttccgggtt ctatcggtca gaaccagact ccgggcaaag
     2581 tgttcaaagg caagaaaatg gcaggtcaga tgggtaacga acgtgtaacc gttcagagcc
     2641 ttgacgtagt acgcgttgac gctgagcgca acctgctgct ggttaaaggt gctgtcccgg
     2701 gtgcaaccgg tagcgacctg atcgttaaac cagctgtgaa ggcgtaagga gatagcaatg
     2761 gaattagtat tgaaagacgc gcagagcgcg ctgactgttt ccgaaactac cttcggtcgt
     2821 gatttcaacg aagcgctggt tcaccaggtt gttgttgctt atgcagctgg tgctcgtcag
     2881 ggtactcgtg ctcagaagac tcgtgctgaa gtaactggtt ccggtaaaaa accgtggcgc
     2941 cagaaaggca ccggccgtgc gcgttctggt tctatcaaga gcccgatctg gcgttctggt
     3001 ggcgtgacct ttgctgctcg tccgcaggac cacagtcaaa aagttaacaa gaagatgtac
     3061 cgcggcgcgc tgaaaagcat cctgtccgaa ctggtacgtc aggatcgtct gatcgttgtc
     3121 gagaagttct ctgtagaagc gccgaaaact aagctgctgg cacagaaact gaaagacatg
     3181 gctctggaag atgtgctgat catcaccggt gagctggacg aaaacctgtt cctggctgcg
     3241 cgcaacctgc acaaggttga cgtacgcgat gcaactggta tcgacccggt tagcctgatc
     3301 gccttcgaca aagtcgtaat gactgctgat gctgttaagc aagttgagga gatgctggca
     3361 tgattcgtga agaacgtctg ctgaaggtgc tgcgtgcacc gcacgtttct gaaaaagcgt
     3421 ctactgcgat ggaaaaatct aacaccatcg tactcaaagt tgctaaagac gcgaccaaag
     3481 cagaaatcaa agctgctgtg cagaaactgt ttgaagtcga agtcgaagtc gttaacaccc
     3541 tggtagttaa agggaaagtt aaacgtcacg gacagcgtat cggtcgtcgt agcgactgga
     3601 aaaaagctta cgtcaccctg aaagaaggcc agaatctgga cttcgttggc ggcgctgagt
     3661 aagtcggagg agtaatacaa tggcagttgt taaatgtaaa ccgacatctc cgggtcgtcg
     3721 ccacgttgtt aaagtggtta accctgagct gcacaagggc aaaccttttg ctccgttgct
     3781 ggaaaaaaac agcaaatccg gtggtcgtaa caacaatggc cgtatcacca ctcgtcatat
     3841 cggtggtggc cacaagcagg cttaccgtat tgttgacttc aaacgcaaca aagacggtat
     3901 cccggcagtt gttgaacgtc ttgagtacga tccgaaccgt tccgcgaaca tcgcgctggt
     3961 tctgtacaaa gacggtgaac gccgttacat cctggcccct aaaggcctga aagctggcga
     4021 ccagattcag tctggcgttg atgctgcaat caaaccaggt aacaccctgc cgatgcgcaa
     4081 catcccggtt ggttctactg ttcataacgt agaaatgaaa ccaggtaaag gcggtcagct
     4141 ggcacgttcc gctggtactt acgttcagat cgttgctcgt gatggtgctt atgtcaccct
     4201 gcgtctgcgt tctggtgaaa tgcgtaaagt agaagcagac tgccgtgcaa ctctgggcga
     4261 agttggcaat gctgagcata tgctgcgcgt tctgggtaaa gcaggtgctg cacgctggcg
     4321 tggtgttcgt ccgaccgttc gcggtaccgc gatgaacccg gtagaccacc cacatggtgg
     4381 tggtgaaggt cgtaactttg gtaagcaccc ggtaactccg tggggcgttc agaccaaagg
     4441 taagaagacc cgcagcaaca agcgtactga taaattcatc gtacgtcgcc gtagcaaata
     4501 attttagagg ataagccatg ccacgttctc tcaagaaagg tccttttatt gacctgcact
     4561 tgctgaagaa ggtagagaaa gcggtggaaa gcggagacaa gaagcccctg cgcacttggt
     4621 cccgtcgttc aacgatcttt cctaacatga tcggtttgac catcgctgtc cataatggtc
     4681 gtcagcacgt tccggtattt gtaaccgacg aaatggtcgg tcacaaactg ggtgaattcg
     4741 caccgactcg tacttatcgc ggccacgctg ctgataaaaa agcgaagaag aaataaggta
     4801 ggaggaagag atggaaacta tcgctaaaca tcgccatgct cgttcttctg ctcagaaggt
     4861 tcgccttgtt gctgacctga ttcgcggtaa gaaagtgtcg caggctctgg atattttgac
     4921 ctacaccaac aagaaagcgg ctgtactggt caagaaagtt ctggaatctg ccattgctaa
     4981 cgctgaacac aacgatggcg ctgacattga cgatctgaaa gttacgaaaa ttttcgtaga
     5041 cgaaggcccg agcatgaagc gcattatgcc gcgtgcaaaa ggtcgtgcag atcgcatcct
     5101 gaagcgcacc agccacatca ctgtggttgt gtccgatcgc tgagactctg gagactagca
     5161 atgggtcaga aagtacatcc taatggtatt cgcctgggta ttgtaaaacc atggaactct
     5221 acctggtttg cgaacaccaa agaattcgct gacaacctgg acagcgattt taaagtacgt
     5281 cagtacctga ctaaggaact ggctaaagcg tccgtatctc gtatcgttat cgagcgtccg
     5341 gctaagagca tccgtgtaac cattcacact gctcgcccgg gtatcgttat cggtaaaaaa
     5401 ggtgaagacg tagaaaaact gcgtaaggtc gtagcggaca tcgctggcgt tcctgcacag
     5461 atcaacatcg ccgaagttcg taagcctgaa ctggacgcaa aactggttgc tgacagcatc
     5521 acttctcagc tggaacgtcg cgttatgttc cgtcgtgcta tgaagcgtgc tgtacagaac
     5581 gcaatgcgtc tgggcgctaa aggtattaaa gttgaagtta gcggccgtct gggcggcgcg
     5641 gaaatcgcac gtaccgaatg gtaccgcgaa ggtcgcgtac cgctgcacac tctgcgtgct
     5701 gacatcgact acaacacctc tgaagcgcac accacttacg gtgtaatcgg cgttaaagtg
     5761 tggatcttca aaggcgagat cctgggtggt atggctgctg ttgaacaacc ggaaaaaccg
     5821 gctgctcagc ctaaaaagca gcagcgtaaa ggccgtaaat aaggagcgtc gctgatgtta
     5881 caaccaaagc gtacaaaatt ccgtaaaatg cacaaaggcc gtaaccgcgg tctggcgcag
     5941 ggtacggatg ttagcttcgg cagcttcggt ctgaaagctg ttggccgtgg tcgtctgact
     6001 gcacgtcaga tcgaagcagc acgtcgtgct atgacccgtg cagttaagcg tcaaggtaag
     6061 atctggatcc gtgtgttccc ggacaaaccg atcactgaaa agccgctggc agtgcgtatg
     6121 ggtaaaggta aaggtaacgt ggagtattgg gttgccttga ttcagccggg taaagtcctg
     6181 tatgaaatgg acggtgttcc ggaagagctg gcccgtgaag cattcaagct ggcagcagcg
     6241 aaactgccga ttaaaaccac ctttgtaact aagacggtga tgtaatgaaa gcaaaagagc
     6301 tgcgtgagaa gagcgttgaa gagctgaaca ccgagctgct gaacctgctg cgtgagcagt
     6361 tcaacctgcg tatgcaggct gcaagtggcc agctgcaaca gtctcacctg ttgaagcaag
     6421 tgcgtcgcga tgtcgcacgc gttaagactt tactgaacga gaaggcgggt gcgtaatgac
     6481 cgataaaatc cgtactctgc aaggtcgcgt tgttagcgac aaaatggaga aatccattgt
     6541 tgttgctatc gaacgttttg tgaaacaccc gatctacggt aaattcatca agcgtacgac
     6601 caaactgcac gtacatgacg agaacaacga atgcggtatc ggtgacgtgg ttgaaatccg
     6661 cgaatgccgt ccgctgtcca agactaaatc ctggacgctg gttcgcgttg tagagaaagc
     6721 ggttctgtaa tacagtacac tctctcgata cgaataaacg gctcagaaat gagccgttta
     6781 ttttttctac ccatatcctt gaagcggtgt tataatgccg cgccctcgat atggggattt
     6841 ttaacgacct gattttcggg tctcagtagt agttgacatt agcggagcac taaaatgatc
     6901 caagaacaga ctatgctgaa cgtcgccgac aactccggtg cacgtcgcgt aatgtgtatc
     6961 aaggttctgg gtggctcgca ccgtcgctac gcaggcgtag gcgacatcat caagatcacc
     7021 atcaaagaag caattccgcg tggtaaggtc aaaaaaggtg atgtgctgaa ggcggtagtg
     7081 gtgcgcacca agaagggtgt tcgtcgcccg gacggttctg tcattcgctt cgatggtaat
     7141 gcttgtgttc ttctgaacaa caacagcgag cagcctatcg gtacgcgtat ttttgggccg
     7201 gtaactcgtg agcttcgtag tgagaagttc atgaaaatta tctctctggc accagaagta
     7261 ctctaaggag cgaatcatgg cagcgaaaat ccgtcgtgat gacgaagtta tcgtgttaac
     7321 cggtaaagat aaaggtaaac gcggtaaagt taagaatgtc ctgtcttccg gcaaggtcat
     7381 tgttgaaggt atcaacctgg ttaagaaaca tcagaagccg gttccggccc tgaaccaacc
     7441 gggtggcatc gttgaaaaag aagccgctat tcaggtttcc aacgtagcaa tcttcaatgc
     7501 ggcaaccggc aaggctgacc gtgtaggctt tagattcgaa gacggtaaaa aagtccgttt
     7561 cttcaagtct aacagcgaaa ctatcaagta atttggagta gtacgatggc gaaactgcat
     7621 gattactaca aagacgaagt agttaaaaaa ctcatgactg agtttaacta caattctgtc
     7681 atgcaagtcc ctcgggtcga gaagatcacc ctgaacatgg gtgttggtga agcgatcgct
     7741 gacaaaaaac tgctggataa cgcagcagca gacctggcag caatctccgg tcaaaaaccg
     7801 ctgatcacca aagcacgcaa atctgttgca ggcttcaaaa tccgtcaggg ctatccgatc
     7861 ggctgtaaag taactctgcg tggcgaacgc atgtgggagt tctttgagcg cctgatcact
     7921 attgctgtac ctcgtatccg tgacttccgt ggcctgtccg ctaagtcttt cgacggtcgt
     7981 ggtaactaca gcatgggtgt ccgtgagcag atcatcttcc cagaaatcga ctacgataaa
     8041 gtcgaccgcg ttcgtggttt ggatattacc attaccacta ctgcgaaatc tgacgaagaa
     8101 ggccgcgctc tgctggctgc ctttgacttc ccgttccgca agtaaggtag ggttactaaa
     8161 tggctaagca atcaatgaaa gcacgcgaag taaaacgcgt agctttagct gataaatact
     8221 tcgcgaaacg cgctgaactg aaagcgatca tctctgatgt gaacgcttcc gacgaagatc
     8281 gttggaacgc tgttctcaag ctgcagactc tgccgcgtga ttccagcccg tctcgtcagc
     8341 gtaaccgctg ccgtcaaaca ggtcgtccgc atggtttcct gcggaagttc gggttgagcc
     8401 gtattaaggt ccgtgaagcc gctatgcgcg gtgaaatccc gggtctgaaa aaggctagct
     8461 ggtaattgtc accaattgaa tcacgggagt aaagacagat gagcatgcaa gatccgatcg
     8521 cggatatgct gacccgtatc cgtaacggtc aggccgcgaa caaagctgcg gtcaccatgc
     8581 cttcctccaa gctgaaagtg gcaatcgcca acgtgctgaa ggaagaaggt tttattgaag
     8641 attttaaagt tgaaggcgac accaagcctg aactggaact tactctgaag tatttccagg
     8701 gcaaagctgt tgtagaaagc attcagcgtg tcagccgccc aggtctgcgc atctataaac
     8761 gtaaagatga gctgccgaaa gttatggcgg gtctgggtat cgcagttgtt tctacctcta
     8821 aaggtgttat gactgatcgt gcagcgcgcc aggctggtct tggtggcgaa attatctgct
     8881 acgtagccta atcggaggaa aaaatgtctc gtgttgctaa agcaccggtc gttgttcctg
     8941 ccggcgttga tgtaaaaatc aacggtcagg ttattacgat caaaggtaaa aacggcgagc
     9001 tgactcgtac tctcaacgat gctgttgaag ttaaacatgc agataatacc ctgaccttcg
     9061 gtccgcgtga tggttacgta gacggttggg cacaggctgg taccgcgcgt gccctgctga
     9121 actcaatggt tatcggtgtt accgaaggct tcactaagaa gctgcagctg gttggtgtag
     9181 gttaccgtgc agcggttaaa ggcaatgtga ttaacctgtc tctgggtttc tctcatcctg
     9241 ttgaccatca gctgcctgcg ggtatcactg ctgaatgtcc gactcagact gaaatcgtgc
     9301 tgaaaggcgc tgataagcag gtgatcggcc aggttgcagc ggatctgcgc gcctaccgtc
     9361 gtcctgagcc ttacaaaggc aagggtgttc gttacgccga cgaagtcgtg cgtaccaaag
     9421 aggctaagaa gaagtaaggt aacactatgg ataagaaatc tgctcgtatc cgtcgtgcga
     9481 cccgcgcacg ccgcaagctc caggagctgg gcgcaactcg cctggtggta catcgtaccc
     9541 cgcgtcacat ttacgcacag gtaattgcac cgaacggttc tgaagttctg gtagccgctt
     9601 ctactgtaga aaaagctatc gctgaacaac tgaagtacac cggtaacaaa gacgcggctg
     9661 cagctgtggg taaagctgtt gctgaacgcg ctctggaaaa aggcatcaaa gatgtatcct
     9721 ttgaccgttc cgggttccaa tatcatggtc gtgtccaggc actggcagat gctgcccgtg
     9781 aagctggcct tcagttctaa ggtagaggtg taagatggct cacatcgaaa aacaagctgg
     9841 cgaactgcag gaaaagctga tcgcggtaaa ccgcgtatct aaaaccgtta aaggtggtcg
     9901 tattttctcc ttcacagctc tgactgtagt tggcgatggt aacggtcgcg ttggttttgg
     9961 ttacggtaaa gcgcgtgaag ttccagcagc gatccagaaa gcgatggaaa aagcccgtcg
    10021 caatatgatt aacgtcgcgc tgaataacgg cactctgcaa caccctgtta aaggtgttca
    10081 cacgggttct cgcgtattca tgcagccggc ttccgaaggt accggtatca tcgccggtgg
    10141 tgcaatgcgc gccgttctgg aagtcgctgg ggttcataac gttctggcta aagcgtatgg
    10201 ttccaccaac ccgattaacg tggttcgtgc aactatcgat ggcctggaaa atatgaattc
    10261 tccagaaatg gtcgctgcca agcgtggtaa atccgttgaa gaaattctgg ggaaataaac
    10321 catggcaaag actattaaaa ttactcaaac ccgcagtgca atcggtcgtc tgccgaaaca
    10381 caaggcaacg ctgcttggcc tgggtctgcg tcgtattggt cacaccgtag agcgcgagga
    10441 tactcctgct attcgcggta tgatcaacgc ggtttccttc atggttaaag ttgaggagta
    10501 agagatgcgt ttaaatactc tgtctccggc cgaaggctcc aaaaaggcgg gtaaacgcct
    10561 gggtcgtggt atcggttctg gcctcggtaa aaccggtggt cgtggtcaca aaggtcagaa
    10621 gtctcgttct ggcggtggcg tacgtcgcgg tttcgagggt ggtcagatgc ctctgtaccg
    10681 tcgtctgccg aaattcggct tcacttctcg taaagcagcg attacagccg aagttcgtct
    10741 gtctgacctg gctaaagtag aaggcggtgt tgtagacctg aacacgctga aagcggctaa
    10801 cattatcggt atccagatcg agttcgcgaa agtgatcctg gctggcgaag taactactcc
    10861 ggtaactgtt cgtggcctgc gtgttactaa aggcgctcgt gctgctatcg aagctgctgg
    10921 cggtaaaatc gaggaataag tagcagatgg ctaaacaacc gggattagat tttcaaagtg
    10981 ccaaaggtgg cttaggcgag ctgaaacgca gactgctgtt tgttatcggt gcgctgattg
    11041 tgttccgtat tggctctttt attccgatcc ctggtattga tgccgctgta cttgccaaac
    11101 tgcttgagca acagcgaggc accatcattg agatgtttaa catgttctct ggtggtgctc
    11161 tcagccgtgc ttctatcttt gctctgggga tcatgccgta tatttcggcg tcgatcatta
    11221 tccagctgct gacggtggtt cacccaacgt tggcagaaat taagaaagaa ggggagtctg
    11281 gtcgtcgtaa gatcagccag tacacccgct acggtactct ggtgctggca atattccagt
    11341 cgatcggtat tgctaccggt ctgccgaata tgcctggtat gcaaggcctg gtgattaacc
    11401 cgggctttgc attctacttc accgctgttg taagtctggt cacaggaacc atgttcctga
    11461 tgtggttggg cgaacagatt actgaacgag gtatcggcaa cggtatttca attattatct
    11521 tcgccggtat tgtcgcggga ctcccgccag ccattgccca tactatcgag caagcgcgtc
    11581 aaggcgacct gcacttcctc gtgttgctgt tggttgcagt attagtattt gcagtgacgt
    11641 tctttgttgt atttgttgag cgtggtcaac gccgcattgt ggtaaactac gcgaaacgtc
    11701 agcaaggtcg tcgtgtctat gctgcacaga gcacacattt accgctgaaa gtgaatatgg
    11761 cgggggtaat cccggcaatc ttcgcttcca gtattattct gttcccggcg accatcgcgt
    11821 catggttcgg gggcggtact ggttggaact ggctgacaac aatttcgctg tatttgcagc
    11881 ctgggcaacc gctttatgtg ttactctatg cgtctgcaat catcttcttc tgtttcttct
    11941 acacggcgtt ggttttcaac ccgcgtgaaa cagcagataa cctgaagaag tccggtgcat
    12001 ttgtaccagg aattcgtccg ggagagcaaa cggcgaagta tatcgataaa gtaatgaccc
    12061 gcctgaccct ggttggtgcg ctgtacatta cctttatctg cctgatcccg gagttcatgc
    12121 gtgatgcaat gaaagtaccg ttctacttcg gtgggacctc actgcttatc gttgttgtcg
    12181 tgattatgga ctttatggct caagtgcaaa ctctgatgat gtccagtcag tatgagtctg
    12241 cattgaagaa ggcgaacctg aaaggctacg gccgataatt ggtcgcccga gaagttacgg
    12301 agagtaaaaa tgaaagttcg tgcttccgtc aagaaattat gccgtaactg caaaatcgtt
    12361 aagcgtgatg gtgtcatccg tgtgatttgc agtgccgagc cgaagcataa acagcgccaa
    12421 ggctgatttt ttcgcatatt tttcttgcaa agttgggttg agctggctag attagccagc
    12481 caatcttttg tatgtctgtg cgtttccatt tgagtatcct gaaaacgggc ttttcagcat
    12541 ggaacgtaca tattaaatag taggagtgca tagtggcccg tatagcaggc attaacattc
    12601 ctgatcataa gcatgccgta atcgcattaa cttcgattta tggcgtcggc aagacccgtt
    12661 ctaaagccat cctggctgca gcgggtatcg ctgaagatgt taagatcagt gagctgtctg
    12721 aaggacaaat cgacacgctg cgtgacgaag ttgccaaatt tgtcgttgaa ggtgatctgc
    12781 gccgtgaaat cagcatgagc atcaagcgcc tgatggatct tggttgctat cgcggtttgc
    12841 gtcatcgtcg tggtctcccg gttcgcggtc agcgtaccaa gaccaacgca cgtacccgta
    12901 agggtccgcg caaaccgatc aagaaataat cggggtgatt gaataatggc aaaggcacca
    12961 attcgtgcac gtaaacgtgt aagaaaacaa gtctctgacg gcgtggctca tatccatgct
    13021 tctttcaaca acaccatcgt gactatcact gatcgtcagg gtaacgcgtt gggttgggca
    13081 acagccggtg gttccggttt ccgtggttct cgcaaatcca ctccgtttgc agctcaggtt
    13141 gcagcagagc gttgcgctga cgccgtgaaa gaatacggca tcaagaatct ggaagttatg
    13201 gttaaaggtc cgggtccagg ccgcgaatct actattcgtg ctctgaacgc cgcaggtttc
    13261 cgcatcacta acattactga tgtgactccg atccctcata acggttgtcg tccgccgaaa
    13321 aaacgtcgcg tataacgcct cgttttccag gtttgttgga gaaagaaaat ggcaagatat
    13381 ttgggtccta agctcaagct gagccgtcgt gagggcaccg acttattcct taagtctggc
    13441 gttcgcgcga tcgataccaa gtgtaaaatt gaacaagctc ctggccagca cggtgcgcgt
    13501 aaaccgcgtc tgtctgacta tggtgtgcag ttgcgtgaaa agcaaaaagt tcgccgtatc
    13561 tatggtgtgc tggagcgtca gttccgtaac tactacaaag aagcagcacg tctgaaaggc
    13621 aacaccggtg aaaacctgtt ggctctgctg gaaggtcgtc tggacaacgt tgtataccgt
    13681 atgggcttcg gtgccactcg tgcagaagca cgtcagctgg ttagccataa agcaattatg
    13741 gtaaacggtc gtgttgttaa catcgcttct tatcaggtta gtccgaatga cgttgtaagc
    13801 attcgtgaga aagcgaagaa gcaatctcgc gtgaaagccg ctctggagct ggctgagcag
    13861 cgtgaaaagc caacctggct ggaagttgat gctggcaaga tggaaggtac gtttaagcgt
    13921 aagccggagc gttctgatct gtctgcggac attaacgaac acctgatcgt cgagctttac
    13981 tccaagtaaa gcttagtacc aaagagagga cacaatgcag ggttctgtga cagagtttct
    14041 aaaaccgcgc ctggttgata tcgagcaagt gagttcgacg cacgccaagg tgacccttga
    14101 gcctttagag cgtggctttg gccatactct gggtaacgca ctgcgccgta ttctgctctc
    14161 atcgatgccg ggttgcgcgg tgaccgaggt tgagattgat ggtgtactac atgagtacag
    14221 caccaaagaa ggcgttcagg aagatatcct ggaaatcctg ctcaacctga aagggctggc
    14281 ggtgagagtt cagggcaaag atgaagttat tcttaccttg aataaatctg gcattggccc
    14341 tgtgactgca gccgatatca cccacgacgg tgatgtcgaa atcgtcaagc cgcagcacgt
    14401 gatctgccac ctgaccgatg agaacgcgtc tattagcatg cgtatcaaag ttcagcgcgg
    14461 tcgtggttat gtgccggctt ctacccgaat tcattcggaa gaagatgagc gcccaatcgg
    14521 ccgtctgctg gtcgacgcat gctacagccc tgtggagcgt attgcctaca atgttgaagc
    14581 agcgcgtgta gaacagcgta ccgacctgga caagctggtc atcgaaatgg aaaccaacgg
    14641 cacaatcgat cctgaagagg cgattcgtcg tgcggcaacc attctggctg aacaactgga
    14701 agctttcgtt gacttacgtg atgtacgtca gcctgaagtg aaagaagaga aaccagagtt
    14761 cgatccgatc ctgctgcgcc ctgttgacga tctggaattg actgtccgct ctgctaactg
    14821 ccttaaagca gaagctatcc actatatcgg tgatctggta cagcgtaccg aggttgagct
    14881 ccttaaaacg cctaaccttg gtaaaaaatc tcttactgag attaaagacg tgctggcttc
    14941 ccgtggactg tctctgggca tgcgcctgga aaactggcca ccggcaagca tcgctgacga
    15001 gtaaccggat cacaggttaa ggttttactg agaaggataa ggtcatgcgc catcgtaaga
    15061 gtggtcgtca actgaaccgc aacagcagcc atcgccaggc tatgttccgc aatatggcag
    15121 gttcactggt tcgtcatgaa atcatcaaga cgactctgcc taaagcgaaa gagctgcgcc
    15181 gcgtagttga gccgctgatt actcttgcca agactgatag cgttgctaat cgtcgtctgg
    15241 cattcgcccg tactcgtgat aacgagatcg tggcaaaact gtttaacgaa ctgggcccgc
    15301 gtttcgcgag ccgtgccggt ggttacactc gtattctgaa gtgtggcttc cgtgcaggcg
    15361 acaacgcgcc gatggcttac atcgagctgg ttgatcgttc agagaaagca gaagctgctg
    15421 cagagtaatc tgaagcaacg taaaaaaacc cgccccggcg ggttttttta tacccatagt
    15481 atccccactt atctacaata gctgtactct ttttgttcat cccctggagt atttatgtgg
    15541 ttacttgacc agtgggcaga gcgccatatt actgaagcac aagctaaagg tgagtttgat
    15601 aatctcccag gcattggtga gccattaatt ctggatgatg attcacacgt accgccggaa
    15661 ctgcgtgctg gctatcgctt gttaaaaaat gctggttgtt taccgccaga acttgagcag
    15721 cgcaaggaag caattcagct tctggatatt ctcaaaggta tccgtcagga tgaccagcaa
    15781 tatcaagagg ttagccgtca gttgtcttta ctggagttga aactgcggca agcaggtttg
    15841 agcactgaat ttttacgtgg cgaatatgct gataagcttc tgaataaaat taatgacaac
    15901 tgagagataa tttatgtatc gcattggtga gttggcaaaa ctggcagaag ttacgcccga
    15961 cacgattcgt tattacgaaa agcagcagat gatggagcat gaagtacgca ccgaaggtgg
    16021 gtttcgcctg tataccgaaa gcgatctcca gcgattgaaa tttatccgcc atgccagaca
    16081 acttggtttc agtctggagt cgatccgcga gttgctgtcg atccgtatcg atcctgaaca
    16141 ccatacctgt caggagtcaa aaggcattgt gcaggaaaga ttgcaggaag tcgaagcacg
    16201 gatagccgag ttgcagagta tgcagcgttc cttgcaacgc cttaacgatg cctgttgtgg
    16261 gaccgcccat agcagtgttt attgctcgat tcttgaagct cttgaacaag gagcgagtgg
    16321 cgttaagagt ggctgttgat tttttgcact ggcaggatta cactcgcgcc gttaaataac
    16381 caactggagt ttttatgagc cgatatcagc atactaaagg gcagataaag gataatgcga
    16441 tagaagcatt actacatgat cccttattcc gacagcgagt agagaaaaat aagaaaggga
    16501 aaggcagtta catgcgaaaa ggaaaacatg gcaatcgggg gaactgggag gccagtggca
    16561 agaaagtaaa tcactttttt accactggcc ttctgctttc aggcgcttgt taagagcggt
    16621 tattctgctc tttcagcaaa tcacgaattt ctgtcagtaa tacttcttct ttagttggtg
    16681 caggtgcggc tgctggttct tcttttttcc gattcagttt gttgattagc ttaatcgcca
    16741 taaagatggc aaaggccaca atcagaaaat caaagacgtt ttgaatgaag acaccgtaat
    16801 gcatcacaac agcagggata tccccctgcg catcgcgtag cgtgacagca aactgtttaa
    16861 agtcgatccc gccaattaat aagcccagag gtggcatgat gatatcggca accagtgaag
    16921 atacaatctt cccgaatgcc gcaccgataa tgacacccac cgccaaatcc accacgttcc
    16981 cgcgcatcgc aaattcgcga aattctttaa taatgctcat gttattctcc ctatgaagcc
    17041 gacaaccata agtctaacaa atgttaagcc attttcctgc caggaatgaa tttaattaat
    17101 ccttgataat caaagggaaa taataaggcg tcattagacg ccttattaat tacaagaaga
    17161 aaggacttgg ctggaacagt ctttcgacgt cggtaataaa ctttttatct gtgaggaaca
    17221 taattacgtg atcgccttgc tcaatgcgca gattgtcatt ggcaatcatc acgtcgtttc
    17281 cacgtaccac cgctccaata atcgttcctg gcggtagctt gatttcatca atgactctgc
    17341 cgacaacgcg tgaggtgctt tcatcaccgt gagcaacggc ttcaatagct tctgctacgc
    17401 cgcggcgcag tgaggaaaca ccaacaatat cagcttttcg cacatggcta agcaacgcag
    17461 aaatagttgc ttgttgcggt gaaatcgcaa tatcgatcac gctcccctga accagatcca
    17521 cataagcgcg acgctggatc aataccatca cctttttcgc acccatacgt ttggcaagca
    17581 tggcggacat gatattggct tcgtcatcgt tggtgacagc aataaacaga tcaacttgat
    17641 cgatatgttc ttcggccagc agttcttgat ccgacgcatc accaaaaaag acgatcgtat
    17701 tctgcaactt ttccgccagt tcggcagcgc gctgctgatt acgttcgatg agtttgacgc
    17761 tgtaatcttt ttccagacga cgcgccagcc ctgcaccgat attaccacca ccaaccagca
    17821 tgatccgctt atacggtttt tccagtcgct gtaattcact catcaccgcg cggatatgct
    17881 gtgaagcggc aataaagaac acttcatcac cagcttcaac aatggtcgaa ccttgcggac
    17941 gaatggggcg atcatggcgg aaaattgctg ccacacgagt atcgatatgt ggcatatgtt
    18001 cgcgcatggt cgaaagtgca ttaccaatca gcgggccgcc gtaataggct ttaaccacag
    18061 ccaggctgac tttaccctca gcgaagttta ccacctgcaa tgcgccggga tactcaatca
    18121 gtcggtaaat attatcgata accaactgct ctggtgcgat cagatgatca atcggtacag
    18181 catctgaatg aaatagctta tcggcatcgc gcacgtagtc tggtgagcgg atacgagcga
    18241 tgcgattagg ggtgttgaaa agtgagtagg ctacctggca ggcaaccata ttggtttcat
    18301 ctgaactggt tacagcaacc agcatatcgg cgtcgtcggc acctgcctcc cgcaatacgc
    18361 gtggatgaga gccatgcccc tgcacgactc gcaggtcaaa tttatcctgc aaggtccgca
    18421 gacgctcacc gttggtatcg acaacagtga tatcgttgtt ctcgccaacc aggttttccg
    18481 ccagtgtgcc gccaacctgg ccggcaccca gaatgataat tttcatcagt cgcgacccgt
    18541 tatctcatca ctttttgatt agcttagcgt aaaagaagcc gtcgccctct tcggcaccag
    18601 gcagattttg tttacccggt tgctctggtg ttcctgtttc gcaaagttcg gcatcagcgg
    18661 tacgttgcaa aaaggcttta atctgcaggc tattctcttc cggtaacact gaacaggtgg
    18721 catagaccag ggttccaccg gattttaaat gcggccaaat ggcgtcgaga atttcagact
    18781 gcaattgcgc gagttccggg atatcgcgat cgcgacgtaa ccatttaata tccggatggc
    18841 gacgaatcac accggttgct gaacaaggcg catctaataa aatgcgatca aactgttgct
    18901 cgccacacca ttgggaaggg taacggccat caccttgttt cacggttgcc ttcataccaa
    18961 ggcgttttaa attgtcgtaa acgcgagaga ggcgctgctc atcaatatcg accgccagaa
    19021 cttgcgcctc tggagcaacc tcaagaatat gcgttgtttt accgccgggg gcagcgcaaa
    19081 gatccagaat gtgttcacca ttttgtggag caagccaggt catgcaacct tgtgctgaag
    19141 catcctgaac ggtaacccat ccttcttcaa aaccgggtag cgcatgaaca ggtgcaggtg
    19201 tttccagctg tacagcatca gggtaatccg catgcgggaa acctttcatt cctgcttcat
    19261 ccagcaatgc aagccagctg tcgcgggaat gatgcgtacg attaacgcgc agccacattg
    19321 gcggacgctg gttattggct tcgacgatgg attgccactg ctcgggatac gccttttgca
    19381 gacgcttcag caaccaggaa ggatgcagat aacgtgcatc actggcatta aactcggcta
    19441 ataactcatc ttgctgacgc tggaactgac gtaatacacc gttaatcaat cccttaagtt
    19501 gcgggcgctt aattgcaact gcgccttcaa ccgtttcagc cagcgcggca tgaggtggaa
    19561 tgcgggtata aagcagttga tacaaaccaa ccataatcag gtaatgaaca gtacgctgtt
    19621 tgcctgtcat cggacgggcc attagcttat taatcagcca gtctaactgt gaaagcgtac
    19681 gcagtacgcc aaagcacaac tcttgaagaa gtgctttgtc tttatcagaa actttttgct
    19741 ggagcggtgg cagaatgttg cttaatgatt gcccttgctc gacgacttgt tcaacggcct
    19801 gggccgccat gctacgtaaa ttacgttgtt ttttcataag tataaaaatg cccggcaaga
    19861 ccgggcttag aagagtggac tatcaggcca gacggttgcc cggaacaaac cattcccgac
    19921 gagaattcag gaggtcttgt gcgctcatcg ctttcttacc cgcaggttgc aacgagagca
    19981 gattcaggat gccatcaccg gtcgcgacct gaatgccttg tttgctggct tcaaggattg
    20041 ttcctggcgc agactttgtc accgtatcaa tgaccgacgc tttccagacc ttaacaggct
    20101 ggccttcaat ttccagccag ctcattggcc atggattaaa agcgcgaatg cagcgttcaa
    20161 gctgtgccgc cgaaagcgac cagtcaatac gcgcttcttc tttactcaat ttttcagcgt
    20221 aagtgacgag agtttcgtcc tgaacttctg gtttcgccgt gccgtctgcc agttgtttca
    20281 acgtagtaat aagcccttgt gggccaagct ctgccagttt gtcgtacagc gtaccactgg
    20341 tatcttctgc ggtaatcggg caggagagct tatagagcat gtcaccggtg tctaaaccaa
    20401 tatccatttg cataatggtt acgccggttt ctgcatcgcc cgcccacagc gaacgttgga
    20461 ttggcgcggc accgcgccag cgcggcagca gtgaaccatg aacgttgata cagccaagac
    20521 gcggcatctc caacactgct ttaggcagaa ttaagccata ggcgacgaca accataacat
    20581 cagcctgtag atcggcgacc agttgctggt tttcttgtgg acgcagggaa acaggttgaa
    20641 aaacgggcag acctttttcc tcagccagaa ctttaaccgg gctgggcatc agttttttac
    20701 cgcgtcctgc cggtcggtct ggctgggtga acacgccaac gacgttatga ccagaagaca
    20761 acagcgcgtc gagatgacgc gctgcaaagt caggtgtacc cgcaaaaata atacgtagtg
    20821 attctgacac gttagttctt atccttaagc ccgggctttc agacgatcca gtttttcaac
    20881 tttctgacga atacgttgtt gtttcagcgg tgacagataa tccataaaca gtttgccgac
    20941 caggtgatcc atctcatgct gaatacagat ggctaacaga ccctctgctt ccagttcaaa
    21001 tggtttaccg tcgcggtcca gggcgcgaat tttaactttc tctgcgcgtg gcactaaagc
    21061 acgttgttca gggatcgaca ggcatccttc ttcaatgcct gtttcgccgc ttttttctaa
    21121 aagctccgga ttgattaaca ccagccgttc gtcacggttt tccgaaacat caataacaat
    21181 gatacgttga tggatatcga cctgggttgc cgccaggcca ataccttctt ctgcgtacat
    21241 cgtctcgaac atatcatcga cgatacgctg aatttctgca ttcacttctt ctaccggttt
    21301 agcaactttg cgaagccgct cgtccggaat atgtaacact tgcaaaactg acataaatct
    21361 ccagagatgt gttcaggagt tagaaagatt atttcttcta ttctagacaa atccccctct
    21421 gattgacagc atcactgacc aatcgcaaag attgctaagg ctgcttatgg cagggagata
    21481 aggatggtcg atacagaaat ttggctgcgt ttaatgagcg tcagcagctt gtacggcgat
    21541 gatatggtcc gtatagctca ctggctggca aaacagtcgc atattgatgc ggttgtattg
    21601 cagcaaacag ggcttacatt gcggcaggca caacgctttc tttcatttcc gcgaaagagt
    21661 atcgaaagct cactttgttg gttggagcaa cccaaccatc atttaatctc tgcggacagc
    21721 gaattttatc ctcctcaact tctggcgacg acagattacc ccggcacact gtttgttgaa
    21781 ggagaactgc acgcgttgca ttcatttcag cttgccgtag tggggagtcg ggcgcattca
    21841 tggtatggcg agcgatgggg acgattattt tgcgaaactc tggcgacgcg tggagtgaca
    21901 attacgagtg gactggcgcg tggaatcgat ggtgtggcgc ataaagcggc cttacaggta
    21961 aatggcgtca gcattgctgt attggggaat ggacttaata ctattcatcc ccgccgccat
    22021 gctccactgg ctgccagtct acttgaacag ggtggtgctc tcgtctcgga atttcccctt
    22081 gatgttcctc cccttgctta caatttccca cgaagaaatc gcattatcag tggtctaagt
    22141 aaaggtgtac tggtggtgga agcggctttg cgcagtggtt cgctggtgac agcacgttgt
    22201 gcgcttgagc aggggcgtga agtttttgcc ttgccgggtc cattagggaa tccgggaagc
    22261 gaagggcctc actggttaat aaaacaaggt gcgattcttg tgacggaacc ggaagaaatt
    22321 ctggaaaact tgcaatttgg attgcactgg ttgccagacg cccctgaaaa ttcattttat
    22381 tcaccagatc aggaagacgt ggcattgcca tttcctgagc tcctggctaa cgtaggagat
    22441 gaggtaacac ctgttgacgt cgtcgctgaa cgtgccggcc aacctgtgcc agaggtagta
    22501 actcaactac tcgaactgga gttagcagga tggatcgcag ctgtacccgg cggctatgtc
    22561 cgattgagga gggcatgcca tgttcgacgt actaatgtat ttgtttgaaa cctatattca
    22621 cacagaagct gagttgcgtg tggatcaaga caaacttgaa caggatctta ccgacgcagg
    22681 atttgatcga gaagatatct acaatgccct gctttggctg gaaaagcttg cggattatca
    22741 ggaaggactg gcagaaccga tgcaactggc ctctgatcca ctctccatgc gtatttatac
    22801 ccctgaagag tgtgaaaggc tggatgccag ctgtcgtggt tttctgcttt tccttgagca
    22861 aattcaggtg cttaaccttg aaacccgtga aatggtgata gagcgagtgc tcgcgctgga
    22921 taccgcagag ttcgacctgg aagacctgaa atgggtaatc ctgatggtgt tgttcaatat
    22981 tccgggctgc gaaaatgcgt accagcaaat ggaagaatta ctctttgaag tgaatgaagg
    23041 tatgctgcat taatcatttc tttaattcag cataagttgt tatggcgaaa tcagcactgt
    23101 tcacggtgcg taataatgag tcctgcccaa agtgcggggc tgaactggtt attcgatccg
    23161 ggaaacacgg tccgtttctt ggatgctcac agtatccggc gtgtgactac gtccgtcctc
    23221 tgaaatcttc agcggatgga catatcgtca aagttctgga gggacagatt tgccctgcat
    23281 gcggcgcaaa tctggtctta cgccaggggc gctttggtat gtttgttggt tgcagtaact
    23341 atcctgaatg cgaacatacc gaacttatcg ataaaccgga cgaaacagca attacatgtc
    23401 cccaatgtcg gacgggccat ctggtccagc gccgctcccg ttatggcaaa acatttcatt
    23461 cctgtgatcg ctacccggag tgtcaatttg ccattaactt caaacctata gccggagaat
    23521 gccctgagtg tcattatccg ctactcatcg aaaagaaaac cgcgcagggt gtaaaacact
    23581 tttgtgccag taaacaatgt ggaaagccgg tttcggcgga ataataacgt gaataataac
    23641 ctgcaaggag acgctatcgc agctgcgata gatgtcctca atgaagaacg tgtcatcgcc
    23701 tatcccacgg aagccgtttt cggtgtcggg tgcgatcctg atagcgaaac agcagtgatg
    23761 agactgttgg agttaaaaca gcgtccggtt gataaggggc tgattttaat cgcggcaaat
    23821 tacgagcagc ttaaacccta tattgatgac tgcatgctga ctgatgcgca gcgtgaaacc
    23881 attttttctc gctggccagg tcccgtcacc tttgtctttc ccgcgcctgc gacaacaccg
    23941 cgctggttga cgggccgctt tgattcgctt gctgtacgag tcaccgacca tccgttggtg
    24001 gttgctttgt gccaggctta tggtaaaccg ctggtttcta ccagtgccaa cttgagtgga
    24061 ttgccgcctt gtcgaacagt agacgaagtt cgcgcacaat ttggcgcagc gttcccggtt
    24121 gtgcctggtg aaacgggagg gcgtttaaat ccttcagaaa tccgcgatgc cctgacgggt
    24181 gaactgtttc gacaggggta acataatgga aaactatgct gtttttggta atccaatagc
    24241 ccacagcaaa tcgccattca ttcatcagca atttgctcag caattgaata ttgaacatcc
    24301 ctatgggcgc gtgctggcac ctatcaatga tttcattaac acactgaacg ctttctttag
    24361 tgctggtggt aaaggagcga atgtgacggt gccttttaaa gaagaggcct ttgccagagc
    24421 tgatgaactt actgaacggg cagcgttggc tggtgctgtt aataccctca agcggttaga
    24481 agatggacgc ctgctgggtg acaataccga tggcgtaggc ttgttaagcg atctggaacg
    24541 tctgtctttt atccgccctg gtttacgtat tctactcatc ggcgctggtg gggcgtctcg
    24601 tggtgtatta cttccactcc tttctctgga ctgcgcggtg acaatcacta atcggacggt
    24661 atcccgcgcg gaagagttgg ctaaattgtt tgcgcacacg ggcagtattc aggcgttggg
    24721 tatggacgaa ctggaggggc atgagttcga tctcattatt aatgcaacat ccagtggcat
    24781 cagtggtgat attcccgcga tcccggcatc gctcattcat tcaggcatgt gttgctatga
    24841 catgttctat cagaaaggaa aaacaccttt tctggcatgg tgtgagctgc gaggttcaaa
    24901 gcgtaatgcg gatggattgg ggatgctggt ggcacaggca gctcatgcct ttcttctctg
    24961 gcacggtgtt ctgcctgaca tagaaccagt tataaagcaa ttgcaggagg agttgtccgc
    25021 gtgaatcagg ccatccagtt tccggacagg gaagagtgga acgagagtaa aaaatgcgtt
    25081 tgttttcccg ctcttgtaaa tggtatgcag ctcacttgcg ctattactgg agagagtctg
    25141 gcgaaccgct ttgcaggaga tacgccagaa cagtggttag cgagttttcg tcagcatcgc
    25201 tgggacctgg aagaagaagc agaaaactta attcaggaac aaagtgaaga tgatcaaggt
    25261 tgggtctggt taccttgatc cagatattcg tccttccatt tcacgtagtt atttgcggaa
    25321 tagcgtaacc cagccttctc ttcatcactt aacgggcgga tctgtttgac ggggctaccg
    25381 agatacagat atccgctctt cagccgttta ttttgtggga ccaggctacc cgcaccaatc
    25441 atcacatcat cttctactat tgcaccatca agtaaaattg atgccatccc aaccaacact
    25501 cgattgccaa tggtacagcc gtggagcatc accttatgac caacagtgac atcttcgcca
    25561 atggttaatg ggttgccatc tgggttgtat gaggacttat gggtgacatg caacatactg
    25621 ccatcctgga tattggtgcg tgctccaatc tgtacataat gtacatcacc acgaatcaca
    25681 acgagtggcc agatccccac atcatcagcc aaacgaacgt caccgatcac tacactacta
    25741 tcgtcgatca ttacgcgctg accgatttgt ggaaaaagat cgcggtatgg gcgtaaaaca
    25801 tcagacatac ttacctcaac aataaatgat ttactaatga ctttgggtgc attattggcc
    25861 ttgtgcaagt cttttagtat gcaaaaaagc accgttttgt gtgcaaatgc agcaaaaagg
    25921 gtgaaaaaac aacaaacaga aaaaaagatc aaaaaagtac ttgtgcaaaa aaatgggatc
    25981 cctataatgc gcctccgttg agacgacaat gtgaaacact tcacaagatg gtcggaacaa
    26041 cgaagagaaa aaatcctgaa attcagggtt gactctgaaa gaggaaagcg taatatacgc
    26101 cacctcgcga cagtgagctg aaagc
//
LOCUS       DADXDL010000066        25601 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.066, whole genome shotgun sequence.
ACCESSION   DADXDL010000066 DADXDL010000000
VERSION     DADXDL010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25601)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25601)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25601
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.066"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            286..627
                     /gene="raiA"
                     /locus_tag="IRB70_003214"
     CDS             286..627
                     /gene="raiA"
                     /locus_tag="IRB70_003214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBC0633092.1"
                     /translation="MTMNITSKQMEITPAIRQHVADRLAKLEKWQTHLINPHIILSKE
                     PQGFVADATINTPNGVLVASGKHEDMYTAINELINKLERQLNKLQHKGEARRAATSVK
                     DANFVEEVEEE"
     misc_feature    730..855
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            731..778
                     /gene="pheL"
                     /locus_tag="IRB70_003215"
     CDS             731..778
                     /gene="pheL"
                     /locus_tag="IRB70_003215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheA operon leader peptide PheL"
                     /protein_id="HBC0633093.1"
                     /translation="MKHTPFFFAFFFTFP"
     gene            877..2037
                     /gene="pheA"
                     /locus_tag="IRB70_003216"
     CDS             877..2037
                     /gene="pheA"
                     /locus_tag="IRB70_003216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydratase"
                     /protein_id="HBC0633094.1"
                     /translation="MTSENPLLALREKISALDEKLLALLAERRELAVEVGKAKLLSHR
                     PVRDIDRERDLLERLITLGKAHHLDAHYITRLFQLIIEDSVLTQQALLQQHLNKINPH
                     SARIAFLGPKGSYSHLAARQYAARHFEQFIESGCAKFADIFNQVETGQADYAVVPIEN
                     TSSGAINDVYDLLQHTSLSIVGEMTLTIDHCLLVSGTTDLSTINTVYSHPQPFQQCSK
                     FLNRYPQWKIEYTESTSAAMEKVAQAKSPHVAALGSEAGGTLYGLQVLERIEANQRQN
                     FTRFVVLARKAINVSDQVPAKTTLLMATGQQAGALVEALLVLRNHNLIMTRLESRPIH
                     GNPWEEMFYLDIQANLESAEMQKALKELGDITRSMKVLGCYPSENVVPVDPT"
     gene            complement(2080..3201)
                     /gene="tyrA"
                     /locus_tag="IRB70_003217"
     CDS             complement(2080..3201)
                     /gene="tyrA"
                     /locus_tag="IRB70_003217"
                     /EC_number="1.3.1.12"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000225220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional chorismate mutase/prephenate
                     dehydrogenase"
                     /protein_id="HBC0633095.1"
                     /translation="MVAELTALRDQIDEVDKALLNLLAKRLELVAEVGEVKSRFGLPI
                     YVPEREASMLASRRAEAEALGVPPDLIEDVLRRVMRESYSSENDKGFKTLCPSLRPVV
                     IVGGGGQMGRLFEKMLTLSGYQVRILEQHDWDRAADIVADAGMVIVSVPIHVTEQVIG
                     KLPPLPKDCILVDLASVKNGPLQAMLAAHDGPVLGVHPMFGPDSGSLAKQVVVWCDGR
                     KPEAYQWFLEQIQVWGARLHRISAVEHDQNMAFIQALRHFATFAYGLHLAEENVQLEQ
                     LLALSSPIYRLELAMVGRLFAQDPQLYADIIMSSERNLALIKRYYKRFGEAIELLEQG
                     DKQAFIDSFRKVEHWFGDYAQRFQSESRVLLRQANDNRH"
     gene            complement(3212..4282)
                     /gene="aroF"
                     /locus_tag="IRB70_003218"
     CDS             complement(3212..4282)
                     /gene="aroF"
                     /locus_tag="IRB70_003218"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroF"
                     /protein_id="HBC0633096.1"
                     /translation="MQKDALNNVHITDEQVLMTPEQLKAAFPLSLQQEAQIADSRKTI
                     SDIIAGRDPRLLVVCGPCSIHDPETALEYARRFKALAAEVSDSLYLVMRVYFEKPRTT
                     VGWKGLINDPHMDGSFDVEAGLQIARKLLLELVNMGLPLATEALDPNSPQYLGDLFSW
                     SAIGARTTESQTHREMASGLSMPVGFKNGTDGSLATAINAMRAAAQPHRFVGINQAGQ
                     VALLQTQGNPDGHVILRGGKAPNYSPADVAQCEKEMEQAGLRPSLMVDCSHGNSNKDY
                     RRQPAVAESVVAQIKDGNRSIIGLMIESNIHEGNQSSEQPRSEMKYGVSVTDACISWE
                     MTDALLREIHQDLNGQLTARVA"
     gene            4492..4857
                     /locus_tag="IRB70_003219"
     CDS             4492..4857
                     /locus_tag="IRB70_003219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417093.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2799 domain-containing protein"
                     /protein_id="HBC0633097.1"
                     /translation="MMKKFIAPLLALLVSGCQIDPYTHAPTLTSTDWYDVGMEDAISG
                     STIKDDDAFSDSQADRGLYLKGYAEGQKKTCQTDFTYARGLSGKSFPASCNNVENASQ
                     LHEVWQKGADENASTIRLN"
     gene            5007..5525
                     /locus_tag="IRB70_003220"
     CDS             5007..5525
                     /locus_tag="IRB70_003220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfiR family protein"
                     /protein_id="HBC0633098.1"
                     /translation="MRFSHRLFLLLILLLTGAPILAQEPSDVAKNVRMMVSGIVSYTR
                     WPALSGPPKLCIFSSSHFSNALQENGTTSLPYLPVIIHTQQEAMISGCNGFYFGNESP
                     TFQMELTEQYPSKALLLIAEQNTECIIGSAFCLIIHNNDVRFAVNLDALSRSGVKVNP
                     DVLMLARKKNDG"
     gene            5515..6741
                     /gene="dgcN"
                     /locus_tag="IRB70_003221"
     CDS             5515..6741
                     /gene="dgcN"
                     /locus_tag="IRB70_003221"
                     /EC_number="2.7.7.65"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diguanylate cyclase DgcN"
                     /protein_id="HBC0633099.1"
                     /translation="MMDNDNSLHKRPTFKRALRNISMTSIFITMMLIWLLLSVTSVLT
                     LKQYAQKNLALTAATMTYSLEAAVVFADGPAATETLAALGQQGQFSTAEVRDKQQNIL
                     ASWHYTHKEPGDTFSNFISHWLFPAPIIQPIRHNGETIGEVRLTARDSSISHFIWFSL
                     AVLTGCILLASGIAITLTRHLHNGLVEALKNITDVVHDVRSNRNFSRRVSEERIAEFH
                     RFALDFNSLLDEMEEWQLRLQAKNAQLLRTALHDPLTGLANRAAFRSGINTLMNNSDA
                     RKTSALLFLDGDNFKYINDTWGHATGDRVLIEIAKRLTEFGGLRHKAYRLGGDEFAMV
                     LYDVQSESEVQQICSALTQIFNLPFDLHNGHQTTMTLSIGYAMTIEHASAENLQELAD
                     HNMYQAKHQRAEKLVR"
     gene            6757..7239
                     /locus_tag="IRB70_003222"
     CDS             6757..7239
                     /locus_tag="IRB70_003222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family protein"
                     /protein_id="HBC0633100.1"
                     /translation="MIKHLVAPLIFTSLILTGCQSPQGKFTPEQVAAMQSYGFTESAG
                     DWSLGLSDAILFAKNDYKLLPESQQQIQTMAAKLASTGLTHARMDGHTDNYGEDSYNE
                     ALSLKRANVVADAWAMGGQIPRSNLTTQGLGKKYPIASNKTAQGRAENRRVAVVITTP
                     "
     gene            complement(7316..7663)
                     /gene="rplS"
                     /locus_tag="IRB70_003223"
     CDS             complement(7316..7663)
                     /gene="rplS"
                     /locus_tag="IRB70_003223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012768745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBC0633101.1"
                     /translation="MSNIIKQLEQEQMKQDVPSFRPGDTVEVKVWVVEGSKKRLQAFE
                     GVVIAIRNRGLHSAFTVRKISNGEGVERVFQTHSPVVDSISVKRRGAVRKAKLYYLRE
                     RTGKAARIKERLN"
     gene            complement(7705..8472)
                     /gene="trmD"
                     /locus_tag="IRB70_003224"
     CDS             complement(7705..8472)
                     /gene="trmD"
                     /locus_tag="IRB70_003224"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBC0633102.1"
                     /translation="MWIGIISLFPEMFRAITDYGVTGRAVKNGLLSIQSWSPRDFTHD
                     RHRTVDDRPYGGGPGMLMMVQPLRDAIHAAKAAAGEGAKVIYLSPQGRKLDQAGVSEL
                     ATNQKLILVCGRYEGIDERVIQTEIDEEWSIGDYVLSGGELPAMTLIDSVSRFIPGVL
                     GHEASATEDSFAEGLLDCPHYTRPEVLEGMEVPPVLLSGNHAEIRRWRLKQSLGRTWL
                     RRPELLENLALTEEQARLLAEFKTEHAQQQHKHDGMA"
     gene            complement(8503..9051)
                     /gene="rimM"
                     /locus_tag="IRB70_003225"
     CDS             complement(8503..9051)
                     /gene="rimM"
                     /locus_tag="IRB70_003225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000043333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBC0633103.1"
                     /translation="MSKQLTAQAPVDPIVLGKMGSSYGIRGWLRVFSSTEDAESIFDY
                     QPWFIQKAGQWQQVQLESWKHHNQDMIIKLKGVDDRDAANLLTNCEIVVDSSQLPQLE
                     EGDYYWKDLMGCQVVTTEGYDLGKVVDMMETGSNDVLVIKANLKDAFGIKERLVPFLD
                     GQVIKKVDLTTRSIEVDWDPGF"
     gene            complement(9070..9318)
                     /gene="rpsP"
                     /locus_tag="IRB70_003226"
     CDS             complement(9070..9318)
                     /gene="rpsP"
                     /locus_tag="IRB70_003226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000256453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBC0633104.1"
                     /translation="MVTIRLARHGAKKRPFYQVVVADSRNARNGRFIERVGFFNPIAS
                     EKEEGTRLDLDRIAHWVGQGATISDRVAALIKEVNKAA"
     gene            complement(9455..10816)
                     /gene="ffh"
                     /locus_tag="IRB70_003227"
     CDS             complement(9455..10816)
                     /gene="ffh"
                     /locus_tag="IRB70_003227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBC0633105.1"
                     /translation="MFDNLTDRLSRTLRNISGRGRLTEDNVKDTLREVRMALLEADVA
                     LPVVREFINRVKEKAVGHEVNKSLTPGQEFVKIVRNELVAAMGEENQTLNLAAQPPAV
                     VLMAGLQGAGKTTSVGKLGKFLREKHKKKVLVVSADVYRPAAIKQLETLAEQVGVDFF
                     PSDVGQKPVDIVNAALKEAKLKFYDVLLVDTAGRLHVDEAMMDEIKQVHASINPVETL
                     FVVDAMTGQDAANTAKAFNEALPLTGVVLTKVDGDARGGAALSIRHITGKPIKFLGVG
                     EKTEALEPFHPDRIASRILGMGDVLSLIEDIESKVDRAQAEKLASKLKKGDGFDLNDF
                     LEQLRQMKNMGGMASLMGKLPGMGQIPDNVKSQMDDKVLVRMEAIINSMTMKERAKPE
                     IIKGSRKRRIAAGCGMQVQDVNRLLKQFDDMQRMMKKMKKGGMAKMMRSMKGMMPPGF
                     PGR"
     gene            10983..11774
                     /locus_tag="IRB70_003228"
     CDS             10983..11774
                     /locus_tag="IRB70_003228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417102.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inner membrane protein YpjD"
                     /protein_id="HBC0633106.1"
                     /translation="MPVFALLALVAYSVSLALIVPGLLQKNGGWRRMAIISAVIALVC
                     HAIALEARILPDGDSGQNLSLLNVGSLVSLMICTVMTIVASRNRGWLLLPIVYAFALI
                     NLALATFMPNEYITHLEATPGMLVHIGLSLFSYATLIIAALYALQLAWIDYQLKNKKL
                     AFNQEMPPLMSIERKMFHITQIGVVLLTLTLCTGLFYMHNLFSMENIDKAVLSIVAWF
                     VYIVLLWGHYHEGWRGRRVVWFNVAGAVILTLAYFGSRIVQQLIS"
     gene            11795..13081
                     /locus_tag="IRB70_003229"
     CDS             11795..13081
                     /locus_tag="IRB70_003229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026171.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBC0633107.1"
                     /translation="MEHISTTTLIIILIIMVVISAYFSGSETGMMTLNRYRLRHMAKQ
                     GNRSAKRVEKLLRKPDRLISLVLIGNNLVNILASALGTIVGMRLYGDAGVAIATGVLT
                     FVVLVFAEVLPKTIAALYPEKVAYPSSFLLAPLQILMMPLVWLLNAITRMLMRMMGIK
                     TDIVVSGSLSKEELRTIVHESRSQISRRNQDMLLSVLDLEKMTVDDIMVPRSEIIGID
                     INDDWKSILRQLSHSPHGRIVLYRDSLDDAISMLRVREAWRLMSEKKEFTKETMLRAA
                     DEIYFVPEGTPLSTQLVKFQRNKKKVGLVVNEYGDIQGLVTVEDILEEIVGDFTTSMS
                     PTLAEEVTPQNDGSVIIDGTANVREINKAFNWHLPEDDARTVNGVILEALEEIPVAGT
                     RVRIGEYDIDILDVQDNMIKQVKVFPVKPLRESVAE"
     gene            complement(13135..13728)
                     /gene="grpE"
                     /locus_tag="IRB70_003230"
     CDS             complement(13135..13728)
                     /gene="grpE"
                     /locus_tag="IRB70_003230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBC0633108.1"
                     /translation="MSSKEQKTPEGQAPEEIIMDQHEEIEAVEPEASAEQVDPRDEKI
                     ANLEAQLAEAQTRERDGILRVKAEMENLRRRTELDIEKAHKFALEKFINELLPVIDSL
                     DRALEVADKANPDMSAMVEGIELTLKSMLDVVRKFGVEVIAETNVPLDPNVHQAIAMV
                     ESDDVAPGNVLGIMQKGYTLNGRTIRAAMVTVAKAKA"
     gene            13851..14729
                     /gene="nadK"
                     /locus_tag="IRB70_003231"
     CDS             13851..14729
                     /gene="nadK"
                     /locus_tag="IRB70_003231"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(+) kinase"
                     /protein_id="HBC0633109.1"
                     /translation="MNNHFKCIGIVGHPRHPTALTTHEMLYRWLCAKGYEVIVEQQIA
                     HELQLKNVKTGTLAEIGQLADLAVVVGGDGNMLGAARTLARYDIKVIGINRGNLGFLT
                     DLDPDNAQQQLADVLEGHYISEKRFLLEAQVCQQDCQKRISTAINEVVLHPGKVAHMI
                     EFEVYIDEIFAFSQRSDGLIISTPTGSTAYSLSAGGPILTPSLDAITLVPMFPHTLSA
                     RPLVINSSSTIRLRFSHRRNDLEISCDSQIALPIQEGEDVLIRRCDYHLNLIHPKDYS
                     YFNTLSTKLGWSKKLF"
     gene            14815..16476
                     /gene="recN"
                     /locus_tag="IRB70_003232"
     CDS             14815..16476
                     /gene="recN"
                     /locus_tag="IRB70_003232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBC0633110.1"
                     /translation="MLAQLTISNFAIVRELEIDFHSGMTVITGETGAGKSIAIDALCL
                     CLGGRAEADMVRTGAARADLCARFSLKDTPAALRWLEENQLEDGHECLLRRVISSDGR
                     SRGFINGTAVPLSQLRELGQLLIQIHGQHAHQLLTKPEHQKFLLDGYANETSLLQEMT
                     ARYQLWHQSCRDLAHHQQLSQERAARAELLQYQLKELNEFNPQPGEFEQIDEEYKRLA
                     NSGQLLTTSQNALAVMADGEDANLQSQLYTAKQLVSELIGMDSKLSGVLDMLEEATIQ
                     IAEASDELRHYCDRLDLDPNRLFELEQRISRQISLARKHHVSPEALPQYYQSLLEEQQ
                     QLDDQADSQETLALAVTKHHQQALETARALHQQRQHYAEELAQLITDSMHALSMPHGQ
                     FTIDVKFDEHHLGADGADRIEFRVTTNPGQPMQPIAKVASGGELSRIALAIQVITARK
                     METPALIFDEVDVGISGPTAAVVGKLLRQLGESTQVMCVTHLPQVAGCGHQHYFVSKE
                     TDGAMTETHMQSLDKKARLQELARLLGGSEVTRNTLANAKELLAA"
     gene            16625..16966
                     /gene="bamE"
                     /locus_tag="IRB70_003233"
     CDS             16625..16966
                     /gene="bamE"
                     /locus_tag="IRB70_003233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417107.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamE"
                     /protein_id="HBC0633111.1"
                     /translation="MRCKTLTAAAAVLLMLTAGCSTLERVVYRPDINQGNYLTANDVS
                     KIRVGMTQQQVAYALGTPLMSDPFGTNTWFYVFRQQPGHEGVTQQTLTLTFNSSGVLT
                     NIDNKPALSGN"
     gene            complement(17028..17318)
                     /locus_tag="IRB70_003234"
     CDS             complement(17028..17318)
                     /locus_tag="IRB70_003234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417108.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RnfH family protein"
                     /protein_id="HBC0633112.1"
                     /translation="MPGKIAVEVAYALPEKQYLQRVTLQEGATVEEAIRASGLLELRT
                     DIDLTKNKVGIYSRPAKLSDTVHDGDRVEIYRPLIADPKELRRQRAEKSANK"
     gene            complement(17308..17745)
                     /gene="ratA"
                     /locus_tag="IRB70_003235"
     CDS             complement(17308..17745)
                     /gene="ratA"
                     /locus_tag="IRB70_003235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010376629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin RatA"
                     /protein_id="HBC0633113.1"
                     /translation="MPQISRTALVPYSAEQMYQLVNDVQSYPQFLPGCTGSRILESTP
                     GQMTAAVDVSKAGISKTFTTRNQLTSNQSILMNLVDGPFKKLIGGWKFTPLSQEACRI
                     EFHLDFEFTNKLIELAFGRVFKELAANMVQAFTVRAKEVYSAR"
     gene            17916..18398
                     /gene="smpB"
                     /locus_tag="IRB70_003236"
     CDS             17916..18398
                     /gene="smpB"
                     /locus_tag="IRB70_003236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBC0633114.1"
                     /translation="MTKKKAHKPGSATIALNKRARHEYFIEEEFEAGLALQGWEVKSL
                     RAGKANISDSYVLLRDGEAFLFGANITPMAVASTHVVCDPTRTRKLLLNQRELDSLYG
                     RVNREGYTVVALSLYWKNAWCKVKIGVAKGKKQHDKRSDIKEREWQVDKARIMKNAHR
                     "
     gene            18613..18975
                     /gene="ssrA"
                     /locus_tag="IRB70_003237"
     tmRNA           18613..18975
                     /gene="ssrA"
                     /locus_tag="IRB70_003237"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(19136..23704)
                     /gene="ypjA"
                     /locus_tag="IRB70_003238"
     CDS             complement(19136..23704)
                     /gene="ypjA"
                     /locus_tag="IRB70_003238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311542.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin-like autotransporter YpjA/EhaD"
                     /protein_id="HBC0633115.1"
                     /translation="MNRTNLHYCRRSVLSLLISALIYAPPGMAAFTPDVIGVVNDETV
                     DGSQKVDERGTTNNTHIINHGQQNVYGGISNESLIESGGYQDIGRHNNYVGQANNTTI
                     NGGRQTIHDGGISTGTIIESGNQDVYTGGISNGTTIKGGNSHISGGTANGTIIDGGSQ
                     RVTTQGHVDSTTINKSGSQDVVQGSLATNTTINGGRQYVEQSTVETTTIKNGGEQRVY
                     ESRALDTTIEGGTQSLNSNSTAKNTQIYSGGTQIVDYTSTSDVIEIYSGGVLDVRGGM
                     ATNVTQHDGAALKVTTYDLTVSGTNSEGAFSIHNNVADNVLLENGGHLDVYGSATRTI
                     IKDKGTMSVLTNAKADATRIDNGGVMDVAGNATNTIINGGTQNINNHGIATGTNINSG
                     TQNIKSGGKADTTNISSGSRQIVEKDGTATGSNISAGGSLIVYTGGIAHGVNQETGSA
                     LVANTGAGTDIEGYNKLSRFTIIGGEANYVVLENTGELTVVAKTSAKNTTIDAGGKLI
                     VQKEAKTDSTRLNNGGVLEVQDGGEAKHVEQQSGGALIASTTSGTLIEGTNSYGDAFY
                     IRNSEAKNVVLENAGSLTVVTGSRAVDTIINANGKMDVYGKDVGTVLNSAGTQTIYAS
                     ATSEKANIKGGKQTVYGLATEANIESGEQIVDGGSTDKTHIKGGTQTVQNYGKAINTD
                     IVSGLQQIMVNGTAEGSIINGGSQVVNEGGLAENSVLNDGGTLDVREKGSATGIQQSS
                     QGALVATTRATRVTGTRADGVAFSIEQGAANNILLANGGVLTVESDTTSAKTQVNAGG
                     REIVKTKATATGTTLTGGEQIVEGVANETTINDGGIQTVSANGEAVKTTINEGGTLTV
                     NDNGKATDIIQNSGAALHTSTANGIEISGTHQYGTFSIAGNLATNMLLENGGNLLVLA
                     GTEARDSKVGKGGAMQNLGQDSATKVNSGGQYTLGRSKDEFQALARAEDLQVAGGTAI
                     VYAGTLADASVSGATGSLSLMTPRDNVTPVKLEGAIRITDSATLTIGNGVDTTLTDLT
                     AASRGSVWLNSNNSCAGTSNCEYRVNSLLLNDGDVYLSAQTAAPATTNGIYNTLTTSE
                     LSGSGNFYLHTNVAGSRGDQLVVNNNATGNFKIFVQDTGVSPQSDDAMTLVKTGGGDA
                     SFTLGNTGGFVDLGTYEYVLKSDGNSNWNLTNDVKPNPDPNPNPKPDPKPDPKPDPKP
                     DPTPDPTPTPVPEKRITPSTAAVLNMAATLPLVFDAELNSIRERLNIMKASPHNNNVW
                     GTTYNTRNNVTTDAGAGFEQTLTGMTVGIDSRNDIPEGIATLGAFMGYSHSHIGFDRG
                     GHGSVGSYSLGGYASWEHESGFYLDGIVKLNRFESNVAGKMSSGGAANGSYRSNGLGG
                     HIETGMRFTDGNWNLTPYASLTGFTADNPEYHLSNGMESKSVDTRSIYRELGATLSYN
                     MRLGNGMEVEPWLKAAVRKEFVDDNRVKVNNDGNFVNDLSGRRGIYQAGIKASFSSSL
                     SGHLGVGYSHGAGVESPWNAVAGVNWSF"
     gene            complement(23769..23888)
                     /locus_tag="IRB70_003239"
     CDS             complement(23769..23888)
                     /locus_tag="IRB70_003239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001131457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBC0633116.1"
                     /translation="MPHSYAEYHHFIMMSLMSGEHNTLALSLQDESPGLVPVG"
     gene            complement(24043..24309)
                     /locus_tag="IRB70_003240"
     CDS             complement(24043..24309)
                     /locus_tag="IRB70_003240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000340076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBC0633117.1"
                     /translation="MLRVTTAAHNRGSRPGQNKRLRTLSVGDALLVCKLNRLGRSMWH
                     LVVLLEELCKRGINFRALAQSIFAQQWGDGSCKSKTICDLRVIV"
     gene            complement(24639..25346)
                     /locus_tag="IRB70_003241"
                     /pseudo
     CDS             complement(24639..25346)
                     /locus_tag="IRB70_003241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311544.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
BASE COUNT         6494 a         6681 c         5842 g         6584 t
ORIGIN      
        1 gaaaaagagc cagtcagttg cttaactgac tggcattaca gcccttgagc tgccgttttt
       61 ttattctgtt agttgtgaaa ctgaagcgat ttagtcacta tcgatctcat caaatatggc
      121 tcgctttgag atattcctca agtaaaaaaa cacctcttcc tgcgatttct cacaaaaaag
      181 attcgttgac aaaaagtgac aaaattatga gatttccatc acacattttg acatcaggaa
      241 cggtatgctg aattcaccaa gacgggaaga caagaggtaa aatttatgac aatgaacatt
      301 accagcaaac aaatggaaat tactccggcc atccgccaac atgtcgcaga ccgtctcgcc
      361 aaactggaaa aatggcaaac acatctgatt aatccacata tcattctgtc caaagagcca
      421 caagggtttg ttgctgacgc cacaatcaat acacctaacg gcgttctggt tgccagtggt
      481 aaacatgaag atatgtacac cgcaattaac gaattgatca acaagctgga acggcagctc
      541 aataaactgc agcacaaagg cgaagcacgt cgtgccgcaa catcggtgaa agacgccaac
      601 ttcgtcgaag aagttgaaga agagtagtcc tttatattga gtgtatcgcc aacgcgcctt
      661 cgggcgcgtt ttttgttgac agcgtgaaaa cagtacgggt actgtactaa agtcacttaa
      721 ggaaacaaac atgaaacaca caccgttttt cttcgcattc ttttttacct tcccctgaat
      781 gggaggcgtt tcgtcgtgtg aaacagaatg cgaagacgaa caataaggcc tcccaaatcg
      841 gggggccttt tttattgata acaaaaaggc aacactatga catcggaaaa cccgttactg
      901 gcgctgcgag agaaaatcag cgcgctggat gaaaaattat tagcattact ggcagagcga
      961 cgcgaactgg ccgtcgaggt gggaaaagcc aaactgctct cgcatcgccc ggtacgtgat
     1021 attgatcgtg aacgcgattt gctggaaaga ttaattacgc tcggtaaagc gcaccatctg
     1081 gacgcccatt acattactcg cctgttccag ctcatcattg aagattccgt attaactcag
     1141 caggctttgc tccagcaaca tctcaataaa attaatccgc actcagcacg catcgctttt
     1201 ctcggcccca aaggttctta ttcccatctt gcggcgcgcc agtatgctgc ccgtcacttt
     1261 gagcaattca ttgaaagtgg ctgcgccaaa tttgccgata tttttaatca ggtggaaacc
     1321 ggccaggccg actatgccgt cgtaccgatt gaaaatacca gctccggtgc cataaatgac
     1381 gtttacgatc tgctgcaaca taccagtttg tcgattgttg gcgagatgac gttaactatc
     1441 gaccattgtt tgttggtctc cggcactact gatttatcca ccatcaatac ggtctacagc
     1501 catccgcagc cattccagca atgcagcaaa ttccttaatc gttatccgca atggaagatt
     1561 gaatataccg aaagtacgtc tgcggcaatg gaaaaggttg cacaggcaaa atcaccgcat
     1621 gttgctgcgt tgggaagcga agctggcggc actttgtacg gtttgcaggt actggagcgt
     1681 attgaagcga atcagcgaca aaacttcacc cgatttgtgg tgttggcacg taaagccatt
     1741 aacgtgtctg accaggttcc agcgaaaacg acgttgttaa tggcgaccgg gcaacaagct
     1801 ggtgcgctgg ttgaagcgtt gctggtactg cgcaaccaca atctgattat gacccgtctg
     1861 gagtcacgcc cgattcacgg taatccatgg gaagagatgt tttatctgga tattcaggcc
     1921 aatcttgaat cagcggaaat gcaaaaagca ttgaaagagt taggggacat cacccgttcg
     1981 atgaaggtat tgggctgtta cccaagtgag aacgtagtgc ctgttgatcc aacctgatga
     2041 aaaggtgccg gatgatgtga atcacccggc actggattat tagtgacggt tgtcattcgc
     2101 ctgacgcaat aacacgcggc tttcactctg aaaacgctgt gcgtaatcgc cgaaccagtg
     2161 ctccaccttg cggaaactgt caataaacgc ctgcttatcg ccctgctcca gcaactcaat
     2221 cgcctcgccg aaacgcttat agtaacgttt gattaacgcc agattacgct ctgacgacat
     2281 aataatgtcg gcataaagct gcggatcctg agcaaacagt cgcccaacca tcgccagttc
     2341 aaggcggtaa atcggcgaag agagcgccag aagttgctca agctgaacat tttcttctgc
     2401 caggtgcagc ccataagcaa aagtagcaaa gtggcgcaga gcctgaataa acgccatatt
     2461 ctgatcgtgc tcgacagcgc taatacgatg cagccgagcg ccccagacct gaatttgctc
     2521 cagaaaccat tggtatgctt ccggcttacg tccatcacac cagaccacaa cttgctttgc
     2581 caggctaccg ctgtccgggc cgaacatcgg gtgtaccccc agcaccggac catcatgcgc
     2641 cgccagcatg gcctgtaatg gtccattttt caccgatgcc agatcgacca gaatacaatc
     2701 tttcggtaaa ggcggtaatt tgccgataac ttgctcagta acgtggattg gcacactaac
     2761 aatcaccatt ccggcatcgg caacaatatc agccgctcga tcccagtcat gttgctccag
     2821 aatccgcacc tgataacccg atagtgtcag catcttctcg aacaggcgtc ccatctgacc
     2881 gccaccgccg acgataacca ccggacgcag tgacggacaa agcgttttaa atcctttgtc
     2941 gttttcactg gagtaagatt cacgcatcac ccgacgcaaa acatcctcaa tcagatctgg
     3001 cggtacaccc agagcttccg cctctgcacg ccgcgaggcc agcatagatg cctcgcgctc
     3061 cggaacataa ataggcagtc caaagcggct tttcacctcg ccaacttcag caaccagttc
     3121 cagacgcttc gctaataaat tcagcagcgc tttatcgact tcatcaattt gatcgcgtaa
     3181 tgcggtcaat tcagcaacca taataaacct cttaagccac gcgagccgtc agctgcccgt
     3241 tcagatcctg atgaatttca cgcagcaagg catcggtcat ttcccaacta atgcaggcat
     3301 cggtgacgga tacaccgtat ttcatttcac tgcgcggttg ctcggaagac tgattgccct
     3361 cgtggatatt actttcaatc atcagaccaa taattgagcg attgccatct ttgatttgag
     3421 caaccacgga ttctgccacc gcaggctgac ggcgataatc tttattggaa ttaccgtggc
     3481 tgcaatctac catcagagac gggcgcagtc ccgcctgttc catctctttt tcacattgcg
     3541 caacatccgc agggctatag ttcggcgctt taccaccgcg caggatcaca tgcccgtccg
     3601 gattcccctg agtttgtagc aacgccacct gccctgcctg gttaatgcca acaaaacggt
     3661 gcggctgggc ggcggcacgc atagcgttaa tagccgttgc aaggctgccg tcggtgccgt
     3721 ttttaaaacc aaccggcatg gaaagcccgg aggccatttc acggtgtgtt tgcgattccg
     3781 ttgtacgagc accaattgct gaccagctaa acagatcgcc caggtattgc gggctattcg
     3841 gatctaacgc ttccgtcgcc agtggcagtc ccatattcac cagctcaagc agcaatttac
     3901 gcgcgatctg cagcccggct tctacatcaa aagagccatc catatgggga tcgttaatca
     3961 accctttcca accgacagtg gtacggggtt tttcaaaata gacgcgcatt accagataga
     4021 ggctatcgct gacctctgcg gcaagggctt taaatcgacg agcatattcc agagcagttt
     4081 ccggatcatg aatggaacaa ggaccacaga ctaccaacag acgaggatcg cgcccggcga
     4141 taatatctga aatggtttta cgcgagtcag caatctgggc ttcctgttgc aggcttaatg
     4201 gaaaagcggc cttcagttgt tccggagtca ttaaaacttg ttcgtcggta atatgtacgt
     4261 tattcagcgc gtctttttgc atgatggcga tcctgtttat gctcgtttgc gatagttgat
     4321 cctcagcgag gatgacgtaa cgataacaca taaagtaaag ttttcaatcc atatttcgta
     4381 catttttctt tacacaagca atttattcgc gcttttaacc cttgtttatg tataaataaa
     4441 tttacaccac ctttgaaaac aatccgctat gctttgaaaa aggagaaaga aatgatgaaa
     4501 aagtttattg cccccttgtt ggctttactg gttagcggat gtcagattga tccttatact
     4561 cacgcgccaa ccttgaccag caccgactgg tatgatgtcg gtatggaaga tgcgatatcg
     4621 ggcagcacca taaaagatga cgatgcattt agcgattcac aggcggatcg cggtctatac
     4681 cttaaaggat atgccgaagg acaaaagaaa acttgccaga ccgattttac ttatgcccgg
     4741 ggactttccg gtaaaagctt tcctgccagc tgcaacaatg ttgaaaatgc cagccaactg
     4801 catgaagtat ggcaaaaagg ggctgatgaa aatgccagca caatacgatt aaattaatta
     4861 aacccccaca aataaattaa acatgagatt ctactcattg tgttttattt ctcacattga
     4921 tgacgaccgc atgaaagaat gatattttaa tgagcattct gaaaaaatat cgatgcattt
     4981 cgagcgaaga tggtgaggat ccctgaatgc gtttttctca ccgactgttc ttactgctga
     5041 ttctcctgct gacgggagca ccaatactcg ctcaggaacc ttctgacgtt gcgaaaaacg
     5101 tgcgtatgat ggtttccggt attgtcagtt acacccgctg gcctgcgcta tcagggccac
     5161 caaagttatg tatcttttca tcttcacatt ttagtaacgc cctacaagag aatggcacga
     5221 catctttgcc ttatctacct gtcatcattc acactcaaca agaggcgatg atttcaggct
     5281 gcaatggttt ttattttggc aacgagtcac cgacattcca gatggaatta accgaacaat
     5341 atccgtcaaa ggcgttatta ttaattgccg aacaaaatac cgagtgcatt attggtagcg
     5401 ccttttgtct aatcatccac aataatgacg tcagatttgc cgtaaacctg gatgccttat
     5461 cgcgtagcgg tgtaaaggtc aacccggatg tcttaatgct cgcacggaag aaaaatgatg
     5521 gataacgata attctcttca taagcgcccc acgtttaaaa gagcattacg caacatcagc
     5581 atgaccagca tatttatcac tatgatgctg atctggctgc tgctttccgt gacgtcagtg
     5641 ctaaccctga aacagtacgc gcaaaaaaac ctggcactga cagcagcaac aatgacttac
     5701 agtctggaag cagctgtcgt ttttgccgat ggccctgcag caactgaaac actggcagcg
     5761 ctggggcagc aaggccaatt ttcaactgca gaagtgcgtg ataagcagca aaatattctg
     5821 gcatcctggc attacaccca taaggaacca ggcgatactt tcagcaattt cataagccac
     5881 tggctcttcc ctgcccccat cattcagccg attcgtcaca atggtgaaac cattggcgaa
     5941 gtacgcttaa ctgctcgcga cagttcaatc agccatttta tctggttttc gctcgctgtc
     6001 ctgaccggtt gtattctgct ggcatcaggc atcgcaatta ccctcacccg ccatttgcac
     6061 aatggcctgg ttgaagcgtt aaaaaacatc accgatgtcg tacatgatgt gcgttccaac
     6121 cgcaattttt cccgacgagt ttcggaagaa cgtatcgcag agtttcaccg cttcgctctc
     6181 gacttcaaca gtctgctgga tgaaatggaa gagtggcagc ttcgtttaca ggccaaaaat
     6241 gcgcagcttc tacgtaccgc gctacatgac ccattaaccg ggctggctaa ccgcgcagcg
     6301 tttcgtagcg gcatcaacac gttgatgaac aattccgatg cccgaaaaac gtcggcgtta
     6361 ctatttcttg atggcgataa tttcaaatat atcaatgata cctggggtca tgcgacgggc
     6421 gatagagtct tgattgaaat agcaaaacgg ttaactgaat ttggcgggct gcgacataaa
     6481 gcataccgac tgggcggcga tgaattcgct atggtgctct atgatgtaca atcggaatct
     6541 gaagtgcagc agatatgctc agcactgaca caaattttta atctcccgtt tgatcttcat
     6601 aatggccatc agactaccat gacattaagc attggttacg cgatgaccat tgagcacgcc
     6661 tctgcggaaa atttacaaga gcttgccgat cacaatatgt atcaggccaa acaccagcgt
     6721 gccgaaaagc tggtgagata acaaggatat atcgatatga taaagcacct ggtagcaccc
     6781 ctgattttca cctcactaat actgactggc tgccagtccc ctcagggaaa gtttactcct
     6841 gagcaagtcg ccgctatgca atcttatgga tttactgaat ccgccggcga ctggtcgctg
     6901 ggcttatcag atgccattct gttcgcaaaa aatgactaca aattgctccc ggaaagccag
     6961 caacagatcc aaaccatggc agccaaattg gcctcgacag ggctaacgca tgcccgtatg
     7021 gatggacaca ccgacaacta tggtgaagac agttacaacg aagccttatc attgaaacgg
     7081 gcgaatgtcg tggccgatgc atgggctatg ggtggacaaa ttccgcgcag caatctcacc
     7141 acacaaggtt taggaaaaaa atatcccata gccagtaaca agaccgccca gggccgcgcc
     7201 gagaaccgcc gcgtcgcagt ggtgattaca accccttaaa acacgagcaa acagataaaa
     7261 aaagggccag ccaattggcc agcccttctt aacaggatgt cgcttaagcg aaatcttagt
     7321 taagacgctc tttgatacga gcagccttac cagtacgctc acgcaggtag tacagtttag
     7381 ctttacgaac agcaccacga cgtttgacag aaatgctgtc aactaccgga gagtgagtct
     7441 ggaagacacg ctcaacgcct tcgccgttgg aaattttacg aacagtgaat gcagagtgca
     7501 gaccgcggtt acgaatagcg ataaccacgc cctcgaatgc ctgcagacgt tttttggaac
     7561 cttcaacaac ccatactttc acttccacgg tatcacccgg acggaaggaa ggtacgtcct
     7621 gcttcatctg ctcttgttca agttgcttaa taatgttgct cataatttaa tctcttatcc
     7681 tgggtaaact gatatctcgg gggcttacgc catcccatca tgtttatgtt gctgttgtgc
     7741 gtgttccgtt ttgaactccg ccagcaacct tgcttgctct tcagtcagag ccaggttttc
     7801 cagaagttca ggtcttctaa gccaggtacg gcccagcgac tgtttcaaac gccagcgacg
     7861 tatctcggca tggttgcccg acagtaacac tggcggaact tccatccctt ctaacacctc
     7921 aggccgcgta tagtgcgggc aatccagcaa tccttcagca aaggaatctt ccgttgccga
     7981 ggcctcatgt cccagtactc ccggaataaa ccgggaaacg gagtcaatca gcgtcattgc
     8041 tggtaactca ccaccactga gaacgtaatc gccgattgac cattcttcgt caatttcggt
     8101 ttggatcacg cgctcatcta taccttcgta gcgaccgcac accagaatca atttttgatt
     8161 cgttgccagt tcgctgacgc ccgcttgatc aagcttgcgt ccctgtggtg acagataaat
     8221 cacctttgcg ccttcacccg ccgcggcttt tgctgcatga atggcgtccc gcaagggttg
     8281 caccatcatt aacatccccg gtccgccgcc gtaaggacga tcgtccacgg tacggtgccg
     8341 gtcatgcgtg aagtcgcgag gactccagct ctggatgctc agcaggccat ttttaactgc
     8401 ccggccagtt accccgtaat cggtaattgc gcggaacatt tcaggaaaca ggctaattat
     8461 gccaatccac atagcgccgt cttttaccgt ttatccggtg gtttaaaaac caggatccca
     8521 atctacttcg attgaacgag tagtgagatc gactttcttg ataacctgcc catcgaggaa
     8581 cggtacgaga cgttccttga taccaaacgc atctttcagg tttgccttaa tgacgagaac
     8641 gtcattagat ccggtttcca tcatatcgac gactttaccg agatcgtagc cttcagtggt
     8701 tactacctgg cagcccatca ggtctttcca gtagtagtca ccctcttcaa gctgaggcaa
     8761 ctgcgatgaa tccacgacaa tttcacaatt cgtcagcagg ttcgccgcat cacgatcgtc
     8821 aacgcctttc agcttgatga tcatgtcctg attgtggtgc ttccagcttt ccagctggac
     8881 ttgctgccac tgacccgcct tctggataaa ccagggctga tagtcaaaaa tgctttcggc
     8941 gtcttcggtg gaagaaaaca ctctgagcca cccacgaata ccgtaagacg aacccatttt
     9001 tcccaaaacg atgggatcaa caggtgcttg cgcggtgagt tgtttgctca tcatgaccac
     9061 cgtgacagat taagctgctt tgtttacttc tttgatcagc gcagcaacgc gatcagaaat
     9121 agttgcgccc tggccaaccc agtgagcgat gcgatccaga tccaggcgag tgccttcttc
     9181 tttttcgcta gcgattgggt tgaagaaacc aacgcgctcg atgaagcgac cgttgcgtgc
     9241 attacggctg tcagcgacaa caacctggta gaacggacgc tttttagcgc cgtgacgtgc
     9301 taaacgaata gttaccataa catcctcttg tgtgaataaa acaaccggac cccatcgagg
     9361 aacggagtcc ggtgtcatat taaaagcccg aaaattttac tgatttctgg agaaaatgca
     9421 atcagcagtt aataactctg tcgcataagg tcatttagcg accaggaaat cccggcggca
     9481 tcatcccctt catgcttctc atcatcttcg ccattccgcc cttcttcatt ttcttcatca
     9541 tgcgctgcat gtcgtcgaac tgtttcagaa gacggttaac gtcctgcacc tgcataccgc
     9601 aaccggcggc gatacgacgc ttacgcgaac ctttgatgat ttctggctta gcgcgctctt
     9661 tcatcgtcat cgagttgatg atggcttcca tacgcaccag cactttatcg tccatctgcg
     9721 acttgacgtt atccgggatc tgccccatgc ccggcagttt gcccatcagg ctggccatgc
     9781 cgcccatatt tttcatctgg cgcagttgct caaggaagtc attgagatcg aagccgtcgc
     9841 cttttttcag cttgctggct aatttctcag cttgcgcgcg gtcaactttg ctttcgatat
     9901 cttcgatcag cgacagtacg tcgcccatgc cgagaatacg ggaagcgatg cggtccggat
     9961 ggaacggctc cagcgcctcg gttttctcgc caacaccgag gaacttgatc ggtttgccag
    10021 tgatgtgacg aatagagagc gccgcaccgc cacgagcatc gccgtcgact ttagtcagta
    10081 ccacaccggt cagcggtaac gcttcattga atgcttttgc cgtattggcc gcatcctgac
    10141 cagtcatggc atcaaccaca aacagggttt caaccggatt aatcgacgca tggacttgtt
    10201 tgatctcgtc catcatcgct tcgtcaacgt gcagacgacc ggcggtatcc accagcagca
    10261 cgtcgtagaa tttcagtttg gcttctttca gcgccgcgtt aacgatatct accggcttct
    10321 gaccaacatc agaagggaag aaatcaacgc ccacctgctc tgccagcgtc tcaagctgtt
    10381 tgattgccgc cggacgataa acgtcggcag aaaccaccag cactttcttc ttgtgcttct
    10441 cgcgcaggaa cttaccgagt ttaccaacgc tggttgtttt accggcacct tgcaggcccg
    10501 ccatcagcac gaccgcaggc ggttgcgcag ccaggttcag ggtctggttc tcttcgccca
    10561 tcgccgcaac cagttcgtta cggacaattt tgacgaactc ctgccccggc gtcaggctct
    10621 tattaacttc atgaccaacc gctttctctt ttacgcgatt gataaactca cgcactaccg
    10681 gcagggcgac gtccgcctcc agcagcgcca tgcgcacttc gcgcagcgta tcttttacgt
    10741 tgtcttcagt gaggcgtcca cggccactga tattgcgcag cgtgcgcgac aaacgatcgg
    10801 ttaaattatc aaacattgtc tctcgcctgg ggtggaaacg gttggccgca atcgcgacac
    10861 atcatcagta ttttgccgca gtataacatg aaggcgtctt tgttgttatg caacggttgg
    10921 agcagcgttc acctgacgct atactgcttc tctttcttat tgctcaaact gtcgacatta
    10981 ctatgcccgt ttttgctctg ctcgcgcttg tcgcctactc cgtcagtctt gcgctgattg
    11041 tacccggtct gctgcaaaaa aacggcggct ggcggcgcat ggctattatt tctgcggtca
    11101 ttgcgctggt ctgccacgca atcgctctgg aagcccgcat cctgcccgac ggtgatagcg
    11161 gacaaaacct cagcctgctg aacgttggtt cattggtcag tttgatgatc tgtacggtaa
    11221 tgaccattgt ggcttctcgc aatcgtggct ggttgctgct acccattgtc tatgcctttg
    11281 cgcttatcaa cctggcgctg gcgaccttca tgcccaatga atacataacc catctggaag
    11341 caacgcctgg gatgctggtg cacattggct tatcgctctt ttcctatgcc acgctaatta
    11401 tcgccgccct gtacgcgctg caactggcgt ggattgatta ccaactgaag aacaagaaac
    11461 tagcgtttaa ccaggaaatg ccgccattga tgagtatcga gcgtaaaatg ttccacatca
    11521 cgcagattgg cgtggtgctg ctaacgctca cgctttgcac tggcctgttc tacatgcaca
    11581 acttatttag catggaaaat atcgacaagg ccgtgctctc tatcgtggcg tggtttgtct
    11641 atattgtgct gctgtgggga cattatcatg aaggatggcg tggacgccgc gtcgtctggt
    11701 ttaacgttgc gggtgcagtc attctgacac tggcctactt cggcagccga attgtccagc
    11761 agttaatcag ctaaacccag aaaaggagtt tcccctggaa cacatttcta ctactacgtt
    11821 gatcattatt ctgatcatca tggtggtcat ttcagcctat ttttccgggt ccgaaaccgg
    11881 aatgatgacc ctcaaccgct atcgtctgcg acatatggcg aaacagggta atcgctcggc
    11941 caaacgcgtc gaaaaattgc tgcgtaagcc agaccgcctg attagcctgg tgttaatcgg
    12001 caataacctg gtcaatattc ttgcctccgc gctcggcact attgttggga tgcgtttgta
    12061 cggcgatgcg ggcgtggcaa ttgcgactgg tgtgctgact tttgtcgtac tggtttttgc
    12121 tgaggtattg ccgaaaacca ttgccgcgct gtacccggaa aaagtcgctt atccgagtag
    12181 ttttctgctg gctccgctgc aaattttgat gatgccgctg gtctggttgc tgaatgctat
    12241 tacccgcatg ttaatgcgca tgatgggcat caaaaccgat atcgtggtta gcggctcttt
    12301 gagcaaagaa gagttgcgca ccatcgtgca cgaatcgcgc tcacaaattt cccgtcgcaa
    12361 tcaggatatg ctgctgtcgg tgctcgatct ggaaaaaatg accgttgatg acatcatggt
    12421 gccgcgcagt gaaattatcg gtattgatat caacgatgac tggaaatcga ttctgcgcca
    12481 actctcccac tcacctcacg ggcgcatcgt gctctaccgt gattcgctgg acgacgccat
    12541 cagtatgctg cgtgtgcgtg aagcctggcg actcatgtcg gagaaaaaag agttcaccaa
    12601 agaaaccatg ctacgcgccg cggacgagat ctattttgtc ccggaaggta cgccgctcag
    12661 cacgcagttg gtgaagtttc agcgcaacaa aaagaaagtc ggcctggtcg tcaacgagta
    12721 tggagacatt caggggctgg tgacggttga agatattctg gaagagattg tcggcgattt
    12781 cactacctcg atgtcgccaa cacttgccga agaggtcacg ccgcaaaacg acggttcggt
    12841 gattatcgat ggcaccgcca acgtgcgaga aatcaacaaa gcctttaact ggcatctacc
    12901 tgaagacgat gcccgcacgg ttaatggcgt cattcttgaa gctctggaag agatccctgt
    12961 cgctggcacc cgcgtgcgta ttggcgagta cgatatcgat attctcgacg tacaggataa
    13021 tatgattaag caggtaaaag tttttcctgt gaaaccgctg cgcgagagtg tggcggagta
    13081 aaaaaacggc ccggcattcg catgctgggc cgtgatttat tacgaaagca gaaattaagc
    13141 ttttgccttc gctacagtca ccatcgccgc acgaatcgta cgaccgttca gcgtataacc
    13201 tttctgcata atgcccagta cgttacctgg cgcaacgtca tcagattcca ccattgcgat
    13261 ggcctgatgc acatttgggt ccagtgggac gttggtttcg gcgatcactt caacgccaaa
    13321 cttacgcaca acatccagca tcgacttcag cgtcagctca atgccttcaa ccatcgcgga
    13381 catatccggg ttagctttat cagccacttc cagcgcacga tccaggctat caatcaccgg
    13441 cagcaattcg ttgatgaatt tctccagcgc gaatttgtga gctttttcaa tatccagttc
    13501 agtacgacga cgcaggtttt ccatttcggc ttttacgcgc aaaatgccgt cacgttcacg
    13561 ggtctgggct tcagccagct gagcttcgag attcgcaatt ttttcatcgc gcggatccac
    13621 ctgctcagca gaagcttctg gctcaactgc ctcaatctct tcgtgctgat ccatgataat
    13681 ttcttccggg gcttgcccct caggcgtttt ctgttcttta ctactcatga atttctccgc
    13741 gtttttttcg cattcatctc gctaacttcg cttattatgg ggatcagttt cagggtttca
    13801 agggaagcac tcacattgtc atcaatcttc gcaacaagga cctcggaaaa atgaataatc
    13861 atttcaagtg tattggcatt gtgggacacc cacggcaccc cactgcactg acaacacatg
    13921 aaatgctcta ccgctggctg tgcgcaaaag gttacgaggt catcgttgag caacaaatcg
    13981 ctcacgaact gcaactgaag aatgtgaaaa ctggcacgct cgcggagatt gggcaactgg
    14041 cagatctcgc ggtagttgtt ggtggcgacg gtaatatgct gggcgcggcg cgcacgctcg
    14101 cccgctacga tattaaagtt attggaatca accgtggcaa cctgggtttc ctgactgacc
    14161 ttgatcccga taacgcccag caacaattag ccgatgtgct ggaaggccac tacatcagcg
    14221 agaaacgttt tttgctggaa gcgcaagtct gtcagcaaga ttgccagaaa cgcatcagca
    14281 cggcgattaa cgaagtggta cttcatcctg gcaaagtggc gcatatgatt gagttcgaag
    14341 tgtatatcga cgagatcttt gcgttttcgc agcgttccga tggactgatt atttcgacgc
    14401 caacaggctc caccgcctat tccctctctg cgggcggtcc tattctgaca ccctctctgg
    14461 atgcgattac cctggtgccc atgttcccgc atacgttgtc agcacgacca ctggtcataa
    14521 acagcagcag cacgatccgt ctgcgttttt cgcatcgccg taacgacctg gaaatcagtt
    14581 gcgacagcca gatagcactg ccgattcagg aaggtgaaga tgtcctgatt cgtcgctgtg
    14641 attaccatct gaatcttatt catccgaaag attacagtta tttcaataca ttaagcacca
    14701 agctcggctg gtcaaaaaaa ttattctaat tttacgccag cctctttact gtatataaaa
    14761 ccagtttata ctgtacacaa taacagtaat ggtttttcat acaggaaaac aactatgttg
    14821 gcacaactga ccatcagcaa ctttgctatc gttcgtgagc ttgagattga ttttcatagc
    14881 ggcatgaccg taataactgg cgagaccggc gcgggtaaat ctattgcaat agatgccctc
    14941 tgtctttgtc tcggtggtcg cgctgaagcc gacatggtgc gtaccggcgc tgctcgcgct
    15001 gacctgtgcg cccgtttttc tctgaaagat acgccagcgg ccctgcgctg gctggaagaa
    15061 aaccagcttg aagacgggca tgaatgtttg cttcgtcgcg taatcagcag cgatggtcgc
    15121 tcccgtggtt ttatcaacgg tacagcggtt cctctttcac aactgcgcga actgggtcag
    15181 ttgctgattc agatccatgg tcagcacgct catcagttac tcaccaaacc cgagcaccaa
    15241 aaattcctgc ttgatggcta tgccaatgaa acctctctac tccaggaaat gaccgcacgt
    15301 tatcagttgt ggcatcaaag ctgccgtgac ctcgcgcatc atcaacagtt aagtcaggaa
    15361 cgcgccgccc gtgcagaact gctgcaatac caattaaaag aacttaacga atttaatccg
    15421 cagcccggag agtttgagca aatcgacgaa gagtacaaac gtctggcgaa cagcggtcaa
    15481 ttgctgacta ctagccagaa tgcattggca gtaatggccg acggtgaaga cgcaaacctg
    15541 caaagtcagc tttacacggc taaacaactg gtgagcgaat tgattggcat ggacagcaaa
    15601 ctgtccggcg tacttgatat gctggaagaa gctaccatcc agattgctga agccagcgat
    15661 gaactgcgcc actactgcga tcgtctggat ctcgatccca accgactgtt tgaacttgaa
    15721 cagcgcatct caagacagat ttcgctggca cgtaaacatc acgtcagccc tgaggcattg
    15781 ccacagtatt accagtcgct actggaagaa cagcagcaac tggacgatca ggccgactca
    15841 caagaaacgc tcgcgctggc ggtaacgaaa catcatcagc aggcactgga aacggcgcgc
    15901 gcgttacacc agcaacgcca gcactatgca gaagaacttg cacagctgat caccgacagt
    15961 atgcatgcac tctctatgcc gcatgggcag tttacgatcg atgttaaatt tgacgagcat
    16021 cacctgggcg ctgacggcgc tgatcgtatt gagtttcggg taaccaccaa cccaggtcag
    16081 ccaatgcagc ctattgccaa agtcgcatcc ggtggtgagt tgtcccgcat cgcattggca
    16141 attcaggtca tcacggcgcg taaaatggaa accccggcac tgatttttga tgaagtggat
    16201 gtagggatta gcggcccaac agcggcagtt gtcggcaaac tgctgcgtca acttggcgaa
    16261 tcaactcagg tgatgtgtgt tacccacctg ccacaagtcg cgggatgtgg tcatcaacac
    16321 tattttgtca gcaaagaaac cgatggtgcg atgacagaaa cgcacatgca atccctggat
    16381 aaaaaagcgc ggttacaaga gctggcacgc ctgcttggtg gcagtgaagt cacacgtaac
    16441 acactggcga atgcgaaaga actacttgcg gcgtaaactt ttttcctgct tcacggtcag
    16501 agtaaacagc aaaacgccgt aggaccggaa agcaaaaggt tttaaagtga tgaaaggtct
    16561 attatcatcg gcatattaca gatgagccac gtactgctcg ggcccgaaaa ggaatcaaat
    16621 cactatgcgc tgtaaaacgc tgactgctgc agcagcagta ctattgatgt tgaccgcagg
    16681 ctgttccact ctggagcgag tggtttaccg tcctgacatc aaccagggga attatctgac
    16741 cgctaacgac gtatccaaaa tacgtgttgg catgacgcaa caacaagttg cgtacgcatt
    16801 gggtacaccg ctgatgtccg acccatttgg tacaaatacc tggttctatg tcttccgcca
    16861 gcaacctggt catgaaggtg taacgcagca aacgctgacg ctgaccttta acagtagcgg
    16921 tgtgttgacc aacattgata acaaacctgc gctgagtggt aactaataat aaagttgctc
    16981 tcaaagaggt taaaaaaggt gctcaatgag cacctttttt ctgtctgtta tttattcgct
    17041 gatttttctg ctcgttgcct gcgaagctct ttcggatcgg caatgagagg acgataaatc
    17101 tccacccgat cgccatcatg caccgtatcg ctcagtttgg ccggacggct gtaaatgccg
    17161 actttgtttt tagttaaatc gatatcggta cgcaattcca gcaagccact ggcacgaata
    17221 gcttcttcaa ccgtcgcacc ctcctgcagc gtcacgcgct gcaggtactg cttctcaggt
    17281 agcgcataag ccacctcaac ggcaatttta cctggcactg taaacctctt tcgcacgaac
    17341 cgtaaaagcc tggaccatat tagccgccag ctctttaaac acgcgaccaa aggcgagttc
    17401 aatcaactta ttggtaaact caaagtcgag atgaaactcg atacgacacg cctcctggct
    17461 cagcggcgta aacttccatc caccgatcaa tttcttgaac ggcccatcca ccagattcat
    17521 aagaatactt tggttactgg tcaactggtt gcgggtagta aacgttttgc tgatcccagc
    17581 cttagagaca tctaccgccg cagtcatctg cccaggagtg gactccagaa tccgacttcc
    17641 ggtacaaccc ggcaaaaact gaggataaga ctgaacgtca ttcactaact gatacatttg
    17701 ctccgcgctg tagggtacca gtgcggtccg gctaatctga ggcataacaa tttccatcaa
    17761 caaaaatcca acaaataata tcatttatcc tgctgtaaaa aaaacgctat cccggcgctg
    17821 ggtaacatcg ggttcatgct aagatagagc cttgtccccc gcaggattga tatggggtgt
    17881 tttcgatttc agattaccga tgattcacga cgcttatgac gaagaaaaaa gcacataaac
    17941 ctggttcagc gaccatcgcg cttaacaagc gcgcccggca cgaatacttt atcgaagaag
    18001 agttcgaggc gggacttgcc ctgcaaggct gggaggttaa atccctgcgc gcaggaaaag
    18061 ccaatatcag cgacagctac gtccttctgc gtgacggaga ggcatttctg tttggcgcta
    18121 acatcacgcc aatggctgtg gcctccacgc atgtggtgtg cgatcctacc cgtacccgca
    18181 agttacttct caaccagcgc gaactggact cattgtacgg tcgcgtcaat cgagaaggct
    18241 ataccgtagt ggcgctctcc ctgtactgga aaaatgcctg gtgcaaagtg aaaatcggcg
    18301 tcgccaaagg taagaaacag catgataaac gttcagatat caaagaacgc gaatggcagg
    18361 tggataaagc gcgtatcatg aaaaacgccc accgttaaac ctgcactgca attattgatc
    18421 cgctcctcac cgcgcctccc tctccggcgg cgcgaatgca catcttattg gctatcacat
    18481 ccgacccaaa tgttgccatc ccattgctta atcgaataaa aatcaggcta catgggtgct
    18541 aaatctttaa cgataacgcc attgaggctg gtcatggcac tcatgaatct ggtatactta
    18601 ccgttacaca ttggggctga ttctggattc gacgggattt gcgaaaccca aggtgcatgc
    18661 cgaggggcgg ttggcctcgt aaaaagccgc aaaaaatagt cgcaaacgac gaaaactacg
    18721 ctttagcagc ttaataacct gcttagagcc ctctctccct agcctccgct cttaggacgg
    18781 ggatcaagag aggtcaaacc caaaagagat cgcgtggaag ccctgcctgg ggttgaagcg
    18841 ttaaaactta atcaggctag tttgttagtg gcgtgtccgt ccgcagctgg caagcgaatg
    18901 taaagactga ctaagcatgt agtaccgagg acgtaggaat ttcggacgcg ggttcaactc
    18961 ccgccagctc caccaatcat gattggacgg tgtaaggaca acaccaataa aaacaggaag
    19021 ttagcagtct cagcaggaca ccgaccagac ggtgaggaga caaaaaagga tacgcaaagg
    19081 agccgcggcc cctggtgata tgaaagccca cagatgtggg ctttttcgtt gatggtcaga
    19141 acgaccagtt cacaccagcc actgcgttcc acggggattc cacaccggca ccatggctat
    19201 accccacccc gagatgcccg cttaacgaac tgctgaatga ggctttaata cctgcctggt
    19261 atattccacg tctgcccgac aaatcattga caaaattacc gtcattattc actttcaccc
    19321 ggttatcatc gacaaattct ttgcgcacag ccgccttcag ccacggctca acttccatgc
    19381 cgttccccag acgcatgttg taactcagcg ttgcgcccag ttcacgatat atactgcggg
    19441 tatcgactga tttcgattcc atgccattgg ataaatgata ttcggggtta tcagcggtga
    19501 accccgttaa cgatgcatac ggcgtcaggt tccagttacc atcggtaaat cgcatcccgg
    19561 tttcaatgtg accacccagc ccgttgctgc gataactgcc gttggcggct ccaccgctgc
    19621 tcattttacc ggctacgtta ctttcaaagc ggttcagctt cacgataccg tccagataga
    19681 aaccactttc atgttcccag ctggcatagc cccccagaga ataactgccc acactgccat
    19741 gtcctccacg atcaaaaccg atatgtgaat gggaataacc cataaaagcg cccagcgtcg
    19801 caatcccctc aggaatatca ttacggctat cgatccccac cgtcattccg gtcagcgtct
    19861 gctcaaaccc ggcacccgca tcggtggtga cattattacg ggtgttatac gtcgtccccc
    19921 agacattatt gttgtgtgga ctcgctttca ttatgttcaa ccgctcgcga atactgttta
    19981 gctcagcatc aaagaccaac ggtaatgttg ctgccatatt gagtacggct gccgtagaag
    20041 gcgtgatgcg tttctccggg acgggtgtcg gcgttggatc gggagtcggg tctggtttcg
    20101 gatccggttt tgggtctggt tttggatccg gcttcggatt tgggttgggg tccgggttgg
    20161 gtttgacatc attggtcagg ttccagttgc tgttgccgtc gcttttcagg acatactcat
    20221 aggtcccaag atcaacgaaa ccgccggtat tacccagcgt aaacgaagca tcccctcccc
    20281 ctgttttcac cagcgtcatc gcgtcgtcag actgagggct gacgccggta tcctgaacaa
    20341 agattttaaa attaccagtg gcgttgttgt tgacgaccag ttgatcgccc cgggagcctg
    20401 caacgttggt atgcaggtag aaattaccgc tgccggaaag ttcactggtt gtcagcgtat
    20461 tgtagatacc gttagttgtg gcaggcgctg ctgtttgtgc tgataaataa acatcaccgt
    20521 cgttgaggag caaactgttt actctatatt cgcagttgct ggtacctgca caggaattat
    20581 tgctgttaag ccagacactg ccccggctgg cagccgtcag gtcggtaagc gtcgtatcga
    20641 cgccatttcc gatagttaat gtcgcgctat cggtaatccg gatcgcccct tcgagtttaa
    20701 ctggcgtaac attatcccgt ggcgtcatta acgacaggct tcctgtcgcg ccactgaccg
    20761 atgcatccgc cagcgtacct gcatagacga ttgccgtccc gccagcgacc tggagatctt
    20821 ctgcccgggc cagagcctga aactcatctt ttgaccgccc aagggtatat tgcccgccag
    20881 agttaacctt tgtggcggag tcctgaccca ggttttgcat tgcaccaccc ttgccaacct
    20941 tggagtcacg ggcttcggta cctgctaata ccaataaatt accgccattt tccagcaaca
    21001 tattggtcgc taaattgccg gcaatggaaa aggtaccgta ctggtgagta ccgctgattt
    21061 caataccgtt agccgtgctc gtatggagag cggcaccgct gttctggatg atatctgtcg
    21121 ctttgccatt atcgttgact gtcagcgtac cgccttcatt aatcgttgtt tttactgcct
    21181 caccgttagc cgaaactgtt tgtattccgc cgtcgttaat cgttgtctca ttcgccaccc
    21241 cctcgacgat ttgttcgccg ccggtgagcg tcgtgcctgt cgcagtggct tttgttttga
    21301 cgatctcccg cccgcccgca ttgacctgtg ttttggcgga agtggtgtct gactccacgg
    21361 ttaacacgcc gccatttgcc agcaggatat tgttcgccgc accctgctcg atgctgaacg
    21421 cgacgccatc agcgcgtgtc cctgtgaccc gcgtcgctct ggtggttgca accaacgcgc
    21481 cctggctact ttgctgtatc cccgttgcgc tgcctttctc ccgcacatcg agagtgccgc
    21541 cgtcattaag caccgagttt tcagccagac cgccctcatt aactacctgt gaaccgccat
    21601 taataatgga accttccgct gtcccgttta ccataatttg ttgtaggcca gagacgatat
    21661 cggtattgat cgccttacca taattctgaa cggtttgcgt gccgcctttg atgtgcgttt
    21721 tatctgttga cccaccatca acaatttgtt caccactttc gatatttgcc tcagtggcta
    21781 aaccatatac cgtttgcttg ccacctttga tatttgcttt ttcagaagtg gcactggcat
    21841 atattgtttg ggtacccgca ctattaagta cagtaccaac atcttttcca taaacatcca
    21901 ttttgccgtt ggcattaata atcgtgtcaa ctgcccggga accagtgacg actgttaatg
    21961 agccagcgtt ttccagcact acatttttag cttctgaatt cctgatgtag aaagcatcac
    22021 cataactgtt ggttccttcg ataagtgttc cggaggtcgt ggaagcaatt aatgcgccgc
    22081 cggattgttg ctcaacatgc ttagcctcac caccgtcctg aacctccaga acgccgccat
    22141 tattaagtct ggtgctatct gttttagcct ccttctggac aatcagctta ccgccagcat
    22201 caatggtagt atttttcgcc gaggttttag ccactaccgt cagttcgccg gtattttcca
    22261 gcacaacata attagcctcc cctccgataa tagtgaagcg agagagcttg ttgtatcctt
    22321 cgatatcagt ccctgcgccc gtgttggcaa ctaaagcact gcccgtctcc tggttaaccc
    22381 catgtgcaat accgccggta tagacaatca gcgagcctcc agcgctaata ttgctgccag
    22441 ttgccgtacc atctttctca acaatctgcc ggctcccgga ggatatattt gtcgtgtcag
    22501 ctttcccgcc gctcttgata ttttgcgttc cactgttgat attggtgcca gtggcaatac
    22561 catgattatt aatattctgt gtaccaccat tgattatggt attggtcgcg tttccggcga
    22621 catccataac cccgccatta tctattcggg tcgcatcagc tttagcattc gttaaaactg
    22681 acattgttcc tttatcttta attatcgtcc tggttgccga accatatacg tctaaatgac
    22741 caccattttc cagcaacaca ttgtctgcca cgttattgtg gatggagaat gccccttcac
    22801 tattcgtacc gctcaccgtc aaatcgtaag tcgttacttt taaagcggct ccatcgtgct
    22861 gagtaacatt tgttgccata ccacctctaa catcaagcac gccaccggaa taaatttcaa
    22921 taacatccga ggtgctggtg taatcaacaa tttgcgtacc accagaatag atctgcgtat
    22981 tttttgccgt tgaattacta ttcagagact gagttccgcc ttcaatcgta gtgtccagcg
    23041 cacggctctc atatactctt tgctcaccgc catttttgat ggtggttgtt tctactgtgc
    23101 tctgttcaac atactgtcga ccaccattta tggttgtgtt cgttgccaga cttccttgta
    23161 ctacgtcctg agagccagac ttatttatcg ttgtactgtc gacatgcccc tgagttgtta
    23221 ctcgttggct gccaccatca atgattgttc cattcgcagt ccccccactt atgtgtgaat
    23281 tacccccctt aattgtcgtt ccattgctga taccacctgt ataaacgtcc tgattgccac
    23341 tctcgattat tgtacctgtg gaaatacccc cgtcatgaat tgtctgtctg cccccgttaa
    23401 tggttgtatt attagcctgc cccacataat tgttatgacg tcctatatct tgatatccac
    23461 cagattcaat aagactttca ttagatatcc caccataaac attctgctgg ccatggttga
    23521 taatatgagt gttatttgtt gtacctcgtt catctacttt ttggctgcca tctacagtct
    23581 catcgtttac cacaccaata acatcaggag tgaaggccgc catcccgggc ggggcatata
    23641 tcaaggcaga tatcaataag gaaagtactg agcggcgaca ataatggaga ttggtcctgt
    23701 tcataaattt catcctctga aaagtgaata ctgagtagcg tttaagcgac cttagctttg
    23761 ctgcaacatc agcccacagg caccagacca ggggattcat cctgaagaga cagcgcaagt
    23821 gtattgtgtt caccgctcat caaagacatc atgatgaaat gatgatattc cgcataagaa
    23881 tgaggcattt tttaaacgca gtgcgctgaa gtgtggttgg ataaaaaagt caatctattc
    23941 aggaaacacg gacgtattct tttctttcga caatcaggca gtcggcaaaa taaaatgatt
    24001 tacataatcg tttctgatga atatcttctg ctcacataaa aatcacacaa taactctgag
    24061 atcgcagatt gttttacttt tacagcttcc gtccccccat tgttgggcaa atatagattg
    24121 ggccagagca cgaaagttaa taccacgttt gcacagctcc tccaacagca cgacaagatg
    24181 ccacatactg cgccccagtc ggttcagttt acagactagc agtgcgtccc ctaccgataa
    24241 tgtcctgagc cgtttgttct gtccgggcct gctgccacgg ttatgcgctg cagtggtaac
    24301 tctaagcacg cagttattca gtcaggcgtg gtgcaccgta acgctggtat tgctgggtaa
    24361 gatcaaaaaa ctttcaagca gctaaggaaa gttgaaccag acattagatg aaatatttca
    24421 accaattaca gcaccagttc agacaccgcc aactcatcaa ataaatcaag gggttacgtg
    24481 aaagcgcagc cccttttact ttggtagtgg cagcaaaagg gttgtagtgt aaaggataat
    24541 tccgtttaat cagccaacaa tatatattat ttcaatctac gttattatct cttttaaaaa
    24601 tagccattta tttatcattg aaaactgctt ttagaacttt atacaagggg actattctcc
    24661 acgggatcat ccttagtgga aggatcatca aagtcatcat ccataaataa aatatcatcg
    24721 aatggtgcca cgcccgtgat gagttttatt tttttattac gatcagacaa gactccactt
    24781 aaaccgtttt cgctgacgcg ttctaatgat ttttcataac tctcattgtt agcaggcgta
    24841 ttaaaaatac acggagtatc aacatcaaac aatgacgtcc cccagttcac atatttaata
    24901 tcatagttac tgaagttctg tccagaaaag aagcacccct taaagtccaa tccacctaaa
    24961 ttgtataaac aaccctcttc ttttgggaga gtaattttaa ttctggctat ctcccagaca
    25021 aaattgccat ttttgtattt gaataccgtt tcaagatctc ctccagacag cttgacttct
    25081 ggaaataatt tgaaattaaa ccctacatta ttatgtgtca acgtagatga acaaaagatg
    25141 gaaaaagctt gcagtgctga attatagcta tcgattttat cttgaggctg cgctcttggt
    25201 aaaaacttat agcaacactc ataaaaatta agtagaaact ctgatgacct tccattttta
    25261 tcaaataata cccgctgaaa atgctgcaca aacttattcg ttttttcttg aatatctacg
    25321 gtgtgttcct ttgactctga caaagatgga gcctgttgaa gtgcattgct catctggtta
    25381 atgaacatgt gcatttcttt aaatttatct ccatagtgac ctttaacttg ctgcgagttt
    25441 ttagctacag gtgaaatctt atctatttgg ttgtcatata aattatgtga ttccatacag
    25501 tcatttggcg gcgtttctga aataacacta cgtgttctac ctggctgaag tgaagcaaca
    25561 tgaaaatcac tttttattat attatcgaaa agggcctgtt c
//
LOCUS       DADXDL010000067        25233 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.067, whole genome shotgun sequence.
ACCESSION   DADXDL010000067 DADXDL010000000
VERSION     DADXDL010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25233
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.067"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            70..903
                     /gene="ppsR"
                     /locus_tag="IRB70_003242"
     CDS             70..903
                     /gene="ppsR"
                     /locus_tag="IRB70_003242"
                     /EC_number="2.7.11.33"
                     /EC_number="2.7.4.28"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="posphoenolpyruvate synthetase regulatory
                     kinase/phosphorylase PpsR"
                     /protein_id="HBC0633118.1"
                     /translation="MDNAVDRHVFYISDGTAITAEVLGHAVMSQFPVTISSITLPFVE
                     NESRARAVKDQIDAIYHQTGVRPLVFYSIVLPEIRAIILQSEGFCQDIVQALVAPLQQ
                     EMKLDPTPIAHRTHGLNPNNLNKYDARIAAIDYTLAHDDGISLRNLDQAQVILLGVSR
                     CGKTPTSLYLAMQFGIRAANYPFIADDMDNLVLPASLKPLQHKLFGLTIDPERLAAIR
                     EERRENSRYASLRQCRMEVAEVEALYRKNQIPWINSTNYSVEEIATKILDIMGLSRRM
                     Y"
     gene            1060..2106
                     /gene="aroH"
                     /locus_tag="IRB70_003243"
     CDS             1060..2106
                     /gene="aroH"
                     /locus_tag="IRB70_003243"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase AroH"
                     /protein_id="HBC0633119.1"
                     /translation="MNRTDELRTARIESLVTPAELALRYPVTTGVATHVTDSRRRIEK
                     ILNGEDKRLLVIIGPCSIHDLTAAMEYATRLQSLRNQYQSRLEIVMRTYFEKPRTVVG
                     WKGLISDPDLNGSYRVNHGLELARKLLLQVNELGVPTATEFLDMVTGQFIADLISWGA
                     IGARTTESQIHREMASALSCPVGFKNGTDGNTRIAVDAIRAARASHMFLSPDKNGQMT
                     IYQTSGNPYGHIIMRGGKKPNYHADDIAAACDTLHEFDLPEHLVVDFSHGNCQKQHRR
                     QLEVCEDICQQIRNGSTAIAGIMAESFLREGTQKIVGGQPLTYGQSITDPCLGWEDTE
                     RLVEKLASAVDTRF"
     gene            2238..2429
                     /gene="hemP"
                     /locus_tag="IRB70_003244"
     CDS             2238..2429
                     /gene="hemP"
                     /locus_tag="IRB70_003244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemin uptake protein HemP"
                     /protein_id="HBC0633120.1"
                     /translation="MRYTDSRKLTPETDANHKTASPQPIRRITSQTLLGPDGKLIIDH
                     DGQEYLLRKTQAGKLLLTK"
     gene            complement(2433..3869)
                     /locus_tag="IRB70_003245"
     CDS             complement(2433..3869)
                     /locus_tag="IRB70_003245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiU family protein"
                     /protein_id="HBC0633121.1"
                     /translation="MTLSFITRWCDELPETYTALSPTPLNKARLIWHNAELANTLSIP
                     SSLFKNGAGVWGGETLLPGMSPLAQVYSGHQFGVWAGQLGDGRGILLGEQQLADGTTM
                     DWHLKGAGLTPYSRMGDGRAVLRSTIRESLASEAMHYLGIPTTRALSIVTSDSPVYRE
                     TVESGAMLMRVAPSHLRFGHFEHFYYRREPEKVRQLADFAIRHYWSHLADDEDKYRLW
                     FSDVVARTASLIAQWQTVGFAHGVMNTDNMSLLGLTLDYGPFGFLDDYEPGFICNHSD
                     HQGRYSFDNQPAVALWNLQRLAQTLSPFVAVDALNEALDSYQQVLLTHYGQRMRQKLG
                     FMTEQKEDNALLNELFSLMARERSDYTRTFRMLSLTEQHSAASPLRDEFIDRAAFDDW
                     FARYRRRLQQDEVSDSERQQLMQSVNPALVLRNWLAQRAIEAAEKGDMTELHRLHEAL
                     RNPFSDRDDDYVSRPPDWGKRLEVSCSS"
     gene            complement(3932..4645)
                     /gene="ydiV"
                     /locus_tag="IRB70_003246"
     CDS             complement(3932..4645)
                     /gene="ydiV"
                     /locus_tag="IRB70_003246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-FlhDC factor"
                     /protein_id="HBC0633122.1"
                     /translation="MKIFLENLYHSDCYFLPIRDNQQDLVGVELITHFSSEDGTVRIP
                     TSRVIAQLTEEQHWQLFSEQLELLKSCQHFFIQHKLFAWLNLTPQVATLLLDRDNYAG
                     ELLKYPFIELLINENYPHLDEGKDNRDLFSLSQMYPLVLGNLGAGNSTMKAVFDGLFT
                     RVMLDKSFIQQQITHRSFEPFIRAIQAQISPCCNCIIAGGIDTPEIMAQITPFDFHAL
                     QGCLWPAVPVNQITTLVQR"
     gene            complement(4892..5356)
                     /locus_tag="IRB70_003247"
     CDS             complement(4892..5356)
                     /locus_tag="IRB70_003247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBC0633123.1"
                     /translation="MRFCLILITALFLAGCSHHKAPPPNARLSDSITVIAGLNDQLQS
                     WHGTPYRYGGMTRRGVDCSGFVVVTMRDRFDLQLPRETKEQASIGTQIDKDELLPGDL
                     VFFKTGSGQNGLHVGIYDTNNQFIHASTSKGVMRSSLDNVYWQKNFWQARRI"
     gene            complement(5434..6183)
                     /gene="btuD"
                     /locus_tag="IRB70_003248"
     CDS             complement(5434..6183)
                     /gene="btuD"
                     /locus_tag="IRB70_003248"
                     /EC_number="7.6.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter ATP-binding protein
                     BtuD"
                     /protein_id="HBC0633124.1"
                     /translation="MSIVMQLQDVAESTRLGPLSGEVRAGEILHLVGPNGAGKSTLLA
                     RMAGMTSGKGSIQFAGQPLEAWSATKLALHRAYLSQQQTPPFAMPVWHYLTLHQHDKT
                     RTELLNDVAGALALDDKLGRSTNQLSGGEWQRVRLAAVVLQITPQANPAGQLLLLDEP
                     MNSLDVAQQSALDKILSALCQQGLAIVMSSHDLNHTLRHAHRAWLLKGGKMLASGRRE
                     EVLTPPNLAQAYGMNFRRLDIEGHRMLISTI"
     gene            complement(6183..6734)
                     /gene="btuE"
                     /locus_tag="IRB70_003249"
     CDS             complement(6183..6734)
                     /gene="btuE"
                     /locus_tag="IRB70_003249"
                     /EC_number="1.11.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional thioredoxin/glutathione peroxidase"
                     /protein_id="HBC0633125.1"
                     /translation="MQDSILTTVVKDIDGEVTTLEKYAGNVLLIVNVASKCGLTPQYE
                     QLENIQKAWADRGFVVLGFPCNQFLEQEPGSDEEIKTYCTTTWGVTFPMFSKIEVNGE
                     GRHPLYQKLIAAAPTAVAPEESGFYARMVSKGRAPLYPDDILWNFEKFLVGRDGLVIQ
                     RFSPDMTPEDPIVMESIKLALAK"
     gene            complement(6797..7777)
                     /gene="btuC"
                     /locus_tag="IRB70_003250"
     CDS             complement(6797..7777)
                     /gene="btuC"
                     /locus_tag="IRB70_003250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="vitamin B12 ABC transporter permease BtuC"
                     /protein_id="HBC0633126.1"
                     /translation="MLTLARQQQRQNIRWLLCLSVLMLLALLLSLCAGEQWISPGDWF
                     TPRGELFVWQIRLPRTLAVLLVGAALAISGAVMQALFENPLAEPGLLGVSNGAGVGLI
                     AAVLLGQGQLPNWALGLCAIAGALIITLILLRFARRHLSTSRLLLAGVALGIICSALM
                     TWAIYFSTSVDLRQLMYWMMGGFGGVDWRQSWLMLALIPVLLWICCQSRPMNMLALGE
                     ISARQLGLPLWFWRNVLVAATGWMVGVSVALAGAIGFIGLVIPHILRLCGLTDHRVLL
                     PGCALAGASALLLADIVARLALAAAELPIGVVTATLGAPVFIWLLLKAGR"
     gene            complement(7878..8177)
                     /gene="ihfA"
                     /locus_tag="IRB70_003251"
     CDS             complement(7878..8177)
                     /gene="ihfA"
                     /locus_tag="IRB70_003251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="integration host factor subunit alpha"
                     /protein_id="HBC0633127.1"
                     /translation="MALTKAEMSEYLFDKLGLSKRDAKELVELFFEEIRRALENGEQV
                     KLSGFGNFDLRDKNQRPGRNPKTGEDIPITARRVVTFRPGQKLKSRVENASPKDE"
     gene            complement(8182..10569)
                     /gene="pheT"
                     /locus_tag="IRB70_003252"
     CDS             complement(8182..10569)
                     /gene="pheT"
                     /locus_tag="IRB70_003252"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBC0633128.1"
                     /translation="MKFSELWLREWVNPAIDSDALANQITMAGLEVDGVEPVAGSFHG
                     VVVGEVVECAQHPNADKLRVTKVNVGGDRLLDIVCGAPNCRQGLRVAVATIGAVLPGD
                     FKIKAAKLRGEPSEGMLCSFSELGISDDHSGIIELPADAPIGTDIREYLKLDDNTIEI
                     SVTPNRADCLGIIGVARDVAVLNQLPLVEPEIVPVGATIDDTLPIAVEAPEACPRYLG
                     RVVKGINVKAPTPLWMKEKLRRCGIRSIDAVVDVTNYVLLELGQPMHAFDKDRIEGGI
                     VVRMAKEGETLVLLDGTEAKLNADTLVIADHNKALAMGGIFGGEHSGVNDETQNVLLE
                     CAFFSPLSITGRARRHGLHTDASHRYERGVDPALQHKAMERATRLLIDICGGEAGPVI
                     DISNEATLPKRATITLRRSKLDRLIGHHIADEQVTDILRRLGCEVTEGKDEWQAVAPS
                     WRFDMEIEEDLVEEVARVYGYNNIPDEPVQASLIMGTHREADLSLKRVKTLLNDKGYQ
                     EVITYSFVDPKVQQMIHPGVEALLLPSPISVEMSAMRLSLWTGLLATVVYNQNRQQNR
                     VRIFESGLRFVPDTQAPLGIRQDLMLAGVICGNRYEEHWNLAKETVDFYDLKGDLESV
                     LDLTGKLNEVEFRAEANPALHPGQSAAIYLKGERIGFVGVVHPELERKLDLNGRTLVF
                     ELEWNKLADRVVPQAREISRFPANRRDIAVVVAENVPAADILSECKKVGVNQVVGVNL
                     FDVYRGKGVAEGYKSLAISLILQDTSRTLEEEEIAATVAKCVEALKERFQASLRD"
     gene            complement(10584..11567)
                     /gene="pheS"
                     /locus_tag="IRB70_003253"
     CDS             complement(10584..11567)
                     /gene="pheS"
                     /locus_tag="IRB70_003253"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004851795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBC0633129.1"
                     /translation="MSHLAELVASAKAAISQASDVAALDNVRVEYLGKKGHLTLQMTT
                     LRELPPEERPAAGAVINEAKEQVQQALNTRKAELESAALNARLAAETIDVSLPGRRIE
                     NGGLHPVTRTIDRIESFFGELGFTVATGPEIEDDYHNFDALNIPGHHPARADHDTFWF
                     DATRLLRTQTSGVQIRTMKAQQPPIRIIAPGRVYRNDYDQTHTPMFHQMEGLIVDTNI
                     SFTNLKGTLHDFLRNFFEEDLQIRFRPSYFPFTEPSAEVDVMGKNGKWLEVLGCGMVH
                     PNVLRNVGIDPEVYSGFAFGMGMERLTMLRYSVTDLRSFFENDLRFLKQFK"
     misc_feature    complement(11632..11756)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01859"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Phe leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF01859"
     gene            complement(11706..11750)
                     /gene="pheM"
                     /locus_tag="IRB70_003254"
     CDS             complement(11706..11750)
                     /gene="pheM"
                     /locus_tag="IRB70_003254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pheST operon leader peptide PheM"
                     /protein_id="HBC0633130.1"
                     /translation="MNAAIFRFFFYFST"
     gene            complement(11873..12229)
                     /gene="rplT"
                     /locus_tag="IRB70_003255"
     CDS             complement(11873..12229)
                     /gene="rplT"
                     /locus_tag="IRB70_003255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBC0633131.1"
                     /translation="MARVKRGVIARARHKKILKQAKGYYGARSRVYRVAFQAVIKAGQ
                     YAYRDRRQRKRQFRQLWIARINAAARQNGISYSKFINGLKKASVEIDRKILADIAVFD
                     KVAFTALVEKAKAALA"
     gene            complement(12283..12480)
                     /gene="rpmI"
                     /locus_tag="IRB70_003256"
     CDS             complement(12283..12480)
                     /gene="rpmI"
                     /locus_tag="IRB70_003256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006708231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBC0633132.1"
                     /translation="MPKIKTVRGAAKRFKKTGKGGFKHKHANLRHILTKKATKRKRHL
                     RPKAMVSKGDLGLVIACLPYA"
     gene            complement(12577..13119)
                     /gene="infC"
                     /locus_tag="IRB70_003257"
     CDS             complement(12577..13119)
                     /gene="infC"
                     /locus_tag="IRB70_003257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBC0633133.1"
                     /translation="MKGGKRVQTARPNRINGEIRAQEVRLTGLEGEQLGIVSLREALE
                     KAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGT
                     DEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKDDLQELAVVES
                     FPTKIEGRQMIMVLAPKKKQ"
     gene            complement(13123..15051)
                     /gene="thrS"
                     /locus_tag="IRB70_003258"
     CDS             complement(13123..15051)
                     /gene="thrS"
                     /locus_tag="IRB70_003258"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006894721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBC0633134.1"
                     /translation="MPVITLPDGSQRHYDHAVSPMDVALDIGPGLAKACIAGRVNGEL
                     VDACDLIENDAQLSIITAKDEEGLEIIRHSCAHLLGHAIKQLWPHTKMAIGPVIDNGF
                     YYDVDLDRTLTQEDVEALEKRMHELAEKNYDVIKKKVSWHEARETFANRGESYKVSIL
                     DENIAHDDKPGLYFHEEYVDMCRGPHVPNMRFCHHFKLMKTAGAYWRGDSNNKMLQRI
                     YGTAWADKKALNAYLQRLEEAAKRDHRKIGKQLDLYHMQEEAPGMVFWHNDGWTIFRE
                     LEVFVRSKLKEYQYQEVKGPFMMDRVLWEKTGHWDNYKDAMFTTSSENREYCIKPMNC
                     PGHVQIFNQGLKSYRDLPLRMAEFGSCHRNEPSGSLHGLMRVRGFTQDDAHIFCTEEQ
                     IRDEVNGCIRLVYDMYSTFGFEKIVVKLSTRPEKRIGSDEMWDRAEADLAVALEENNI
                     PFEYQLGEGAFYGPKIEFTLYDCLDRAWQCGTVQLDFSLPSRLSASYVGEDNERKVPV
                     MIHRAILGSMERFIGILTEEFAGFFPTWLAPVQVVIMNITDSQSEYVNELTQKLSNAG
                     IRVKADLRNEKIGFKIREHTLRRVPYMLVCGDKEVESGKVAVRTRRGKDLGSMDVNEV
                     IEKLQQEIRSRSLKQLEE"
     gene            15574..17472
                     /gene="espL1"
                     /locus_tag="IRB70_003259"
     CDS             15574..17472
                     /gene="espL1"
                     /locus_tag="IRB70_003259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system effector EspL1"
                     /protein_id="HBC0633135.1"
                     /translation="MSQNDIIIRTHYKSPHRMHIDSDIPTPSSEPINQFARQLITLLD
                     TSDLSSMLSYCVTQEFTANCRKISQNCYSTALFTINFATSPIHAENILITLHYKKEII
                     SLLLETTPIKANHLRSILDYIEQEQSTAEKRNHCMKLSKKIHREKTIQPTVNLNGSAF
                     FSQSPSDAIFCRHLSLQYALDSLRNGKGKVNLIKHYSSVESIQQHVPLVRDAEFRSLL
                     RHPPAGSRVIASKDFGFALDIFFCRMMANNVSHMSAILYIDNHTLSVRLRIKQSAYGQ
                     LNYVVSVYDPNDTNVAVRGTHRTARGFLSLDKFISSGPDAQTWADMYVRNCAIAFLPL
                     LPEGVPGAIFAGIASRMPFAPIHPSAMLLIMATGQTQQLITLFKQLPILPEKEIIEII
                     TAQNSVGTPALFLAMMNGHTDNVKIFMQEIQSLVDNHIIHEDNLVKLLQTKSANETPG
                     LYISMLYGFDEIIDIFLNALTTPITQELLSKKMVMDILAMKTRDGEPGLYAAMENNHP
                     LCVTRFLSKVYGIAVKYNLSKINIMDLLKGATAHGTPALYIAMSKGNKDVVLSYISTL
                     GTFAKKYSFSQCQLFTLLAAKNHDNMSAVHIAIHHNHYKTVETYYAAINVISQSLSFS
                     ADELKTYL"
     gene            17639..17746
                     /locus_tag="IRB70_003260"
     CDS             17639..17746
                     /locus_tag="IRB70_003260"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588455.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633136.1"
                     /translation="MPTKRFDKKHWKMVVVLLAICGAMLLLRWAAMIWG"
     gene            complement(17799..18557)
                     /locus_tag="IRB70_003261"
     CDS             complement(17799..18557)
                     /locus_tag="IRB70_003261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiY family protein"
                     /protein_id="HBC0633137.1"
                     /translation="MKLLKTVPAIVMLAGGMFASLNAAADDSVFTVMDDPASAKKPFE
                     GNLNAGYLAQSGNTKSSSLTADTTMTWYGQTTAWSLWGNASNTSSNDERSSEKYAAGG
                     RSRFNLTDYDYLFGQASWLTDRYNGYRERDVLTAGYGRQFLNGPVHSFRFEFGPGVRY
                     DKYTDNASETQPLGYASGAYAWQLTDNVKFTQGVSVFGAEDTTLNSESALNVAINEHF
                     GLKVAYNVTWNSEPPESAPEHTDRRTTLSLGYSM"
     gene            18844..19773
                     /gene="pfkB"
                     /locus_tag="IRB70_003262"
     CDS             18844..19773
                     /gene="pfkB"
                     /locus_tag="IRB70_003262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416237.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase II"
                     /protein_id="HBC0633138.1"
                     /translation="MVRIYTLTLAPSLDSATITPQIYPEGKLRCTAPVFEPGGGGINV
                     ARAIAHLGGSATAIFPAGGATGEHLVSLLADENVPVATVEAKDWTRQNLHVHVEASGE
                     QYRFVMPGAALSEDEFRQLEEQVLEIESGAILVISGSLPPGVKLEKLTQLISAAQKQG
                     IRCIVDSSGEALSAALAIGNIELVKPNQKELSALVNRELTQPDDVRKAAQEIVNSGKA
                     KRVVVSLGPQGALGVDSENCIQVVPPPVKSQSTVGAGDSMVGAMTLKLAENASLEEMV
                     RFGVAAGSAATLNQGTRLCSHDDTQKIYAYLSR"
     gene            19874..20164
                     /gene="ghoS"
                     /locus_tag="IRB70_003263"
     CDS             19874..20164
                     /gene="ghoS"
                     /locus_tag="IRB70_003263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type V toxin-antitoxin system endoribonuclease
                     antitoxin GhoS"
                     /protein_id="HBC0633139.1"
                     /translation="MASGDLVRYVITVMLHEDTLTEINELNNYLTRDGFLLTMTDDDG
                     NIHELGTNTFGLISTQSEEEIRELVSGLTQSATGKDPEITITTWEEWNSNRK"
     gene            20270..21130
                     /locus_tag="IRB70_003264"
     CDS             20270..21130
                     /locus_tag="IRB70_003264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBC0633140.1"
                     /translation="MWQAISRLLSEQLGEGEIELRNELPGGEVHAAWHLRYAGRDFFV
                     KCDERELLPGFTAEADQLELLSRSKTVTVPKVWAVGADRDYSFLVMDYLPPRPLDAHS
                     AFILGQQIARLHQWSDQPQFGLDFDNALSTTPQPNTWQRRWSTFFAEQRIGWQLELAA
                     EKGIAFGNIDAIVEHIQQRLASHQPQPSLLHGDLWSGNCALGPDGPYIFDPACYWGDR
                     ECDLAMLPLHTEQPPQIYDGYQSVSPLPADFLERQPVYQLYTLLNRARLFGGQHLVIA
                     QQSLDRLLAA"
     gene            complement(21171..21707)
                     /locus_tag="IRB70_003265"
     CDS             complement(21171..21707)
                     /locus_tag="IRB70_003265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YniB family protein"
                     /protein_id="HBC0633141.1"
                     /translation="MTYQQAGRIAVLKRILGWVIFIPALISTLISLLKFMNTRQENQE
                     GINAVMLDFTHVMIDMMQANTPFLNLFWYNSPTPNFNGGVNVMFWVIFILIFVGLALQ
                     DSGARMSRQARFLREGVEDQLILEKAKGEEGLTREQIESRIVVPHHTIFLQFFSLYIL
                     PVICIAAGYVFFSLLGFI"
     gene            21854..22522
                     /gene="hxpB"
                     /locus_tag="IRB70_003266"
     CDS             21854..22522
                     /gene="hxpB"
                     /locus_tag="IRB70_003266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexitol phosphatase HxpB"
                     /protein_id="HBC0633142.1"
                     /translation="MSTPRQILAAIFDMDGLLIDSEPLWDRAELDVMASLGVDISRRN
                     ELPDTLGLRIDMVVDLWYARQPWNGPSRQEVVERVIARAISLVEETRPLLPGVREAVA
                     LCKEQGLLVGLASASPLHMLEKVLTMFDLRDSFDALASAEKLPYSKPHPQVYLDCAAK
                     LGVDPLTCVALEDSVNGMIASKAARMRSIVVPAPEAQNDPRFVLANVKLSSLTELTAK
                     DLLG"
     gene            22685..23275
                     /locus_tag="IRB70_003267"
     CDS             22685..23275
                     /locus_tag="IRB70_003267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310461.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBC0633143.1"
                     /translation="MTAEGHLLFSIACAVFAKNAELTPVLAQGDWWHIVPSAILTCLL
                     PDIDHPKSFLGQRLKWISKPIARAFGHRGFTHSLLAVFALLATFYLKVPESWFIPADA
                     LQGMVLGYLSHILADMLTPAGVPLLWPCRWRFRLPILVPQKGNQLERFICMALFVWSV
                     WMPHSLPENSAVRWSSQMINTLQIQFHRLIKHQVEY"
     gene            23408..24799
                     /gene="tcyP"
                     /locus_tag="IRB70_003268"
     CDS             23408..24799
                     /gene="tcyP"
                     /locus_tag="IRB70_003268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine/sulfocysteine:cation symporter"
                     /protein_id="HBC0633144.1"
                     /translation="MNFPLIANIVVFVVLLFALAQTRHKQWSLAKKVLVGLVMGVVFG
                     LALHTIYGSDSQVLKDSVQWFNIVGNGYVQLLQMIVMPLVFASILSAVARLHNASQLG
                     KISFLTIGTLLFTTLIAALVGVLVTNLFGLTAEGLVQGGAETARLNAIESNYVGKVSD
                     LSVPQLVLSFIPKNPFADLTGANPTSIISVVIFAAFLGVAALKLLKDDAPKGERVLTA
                     IDTLQSWVMKLVRLVMQLTPYGVLALMTKVVAGSNLQDIIKLGSFVVASYLGLLIMFA
                     VHGILLGINGVSPLKYFRKVWPVLTFAFTSRSSAASIPLNVEAQTRRLGVPESIASFA
                     ASFGATIGQNGCAGLYPAMLAVMVAPTVGINPLDPMWIATLVGIVTVSSAGVAGVGGG
                     ATFAALIVLPAMGLPVTLVALLISVEPLIDMGRTALNVSGSMTAGTLTSQWLKQTDKA
                     ILDSEDDAELAHR"
     gene            complement(24803..>25233)
                     /locus_tag="IRB70_003269"
     CDS             complement(24803..>25233)
                     /locus_tag="IRB70_003269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416244.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633145.1"
                     /translation="LINIKNRLIIHYLRTIYYEQNYIHPVGSIFAAIQKNESLLKFPS
                     IISMLNVNLLFNPLNLPGMGSGVLEEIMSISDSSLRKRLGYEVLSFSLQAHSLSQECI
                     DKLAIFFADDLFKYESVCIAAMEHLKSKATAPIQNGPLPA"
BASE COUNT         6443 a         6440 c         5904 g         6446 t
ORIGIN      
        1 gttctacgct tctgtgcgtt tttaatttat gctttcatag aattatgtct gcatcacggg
       61 aagaacaaaa tggataatgc tgttgatcgc cacgtttttt atatttctga tggtacggca
      121 ataactgcgg aggtattagg acacgcagta atgtcacaat ttcccgtcac tatcagcagc
      181 attacgctgc cgtttgtcga aaatgagagc cgtgcacggg cagtgaagga tcagattgac
      241 gcaatttatc accagacagg tgtgcgcccg ctggtcttct actccatcgt gttgccggag
      301 attcgcgcca tcatcttgca aagtgagggc ttttgccagg atatcgttca ggcactggtt
      361 gccccgctac aacaagagat gaaactggat cccacgccga ttgctcatcg tacccatggc
      421 ctgaacccta ataacctcaa taaatatgat gcgcgtattg cggcgattga ttacaccctt
      481 gcccatgacg acggcatttc gttgcgcaat ctggaccagg ctcaggtgat cctgctcggt
      541 gtttctcgct gtggtaaaac ccccaccagt ctgtatctgg caatgcaatt tggtatccgc
      601 gcggcaaact acccctttat tgccgacgat atggataatc tggtgctacc cgcgtcgctc
      661 aaaccgcttc agcacaaatt gttcggcctg actatcgacc cggaacgtct ggcggcgatt
      721 cgcgaggaac gtcgggagaa cagtcgctat gcctcgcttc gtcagtgcag gatggaagtc
      781 gcggaagtgg aagcgttgta ccgtaaaaat cagatcccgt ggattaacag taccaattat
      841 tcggtagaag agattgccac caagatcctc gatatcatgg gccttagccg tcgaatgtac
      901 tagaaaacta gtgcattggc ttgctttttt gttatcatgc taaccacccg gcgaggtgtg
      961 acacacctcg cacttgaaat cagctgcgat tggtttatcg tgatgcgcat cacttcccgg
     1021 tagtcctgcc gtagaagcaa caaatttctg agacttgtaa tgaacagaac tgacgaactc
     1081 cgtactgcgc gtattgagag cctggtaacg cccgccgaac tcgcgctacg gtatcccgta
     1141 acgactggcg tcgccaccca tgtcaccgac tcccgccgta gaattgaaaa aatactgaat
     1201 ggtgaagata agcgactgtt ggtcattatt ggcccctgct cgatccacga tctcaccgct
     1261 gcgatggagt acgccacccg tctgcagtcg ctgcgcaacc agtaccagtc acggctggaa
     1321 atcgtaatgc gcacctattt tgaaaaacca cgaacagttg tcggctggaa aggactcatc
     1381 tccgatccag atttaaacgg tagctatcgg gtaaatcacg gtctggagct ggcgcgcaaa
     1441 ttacttttac aggtaaatga gctgggcgtc ccaacagcga ctgagttcct cgatatggtg
     1501 accggtcagt ttattgctga tttaatcagt tggggcgcga ttggcgcacg tactaccgaa
     1561 agtcagatcc accgtgaaat ggcttcggca ctctcctgtc cggtaggttt taaaaatggt
     1621 accgatggca acacgcggat tgctgttgat gctatccgcg ctgcccgcgc cagccatatg
     1681 ttcctctcac cagacaaaaa tggtcagatg accatctatc agaccagcgg caacccgtat
     1741 ggccacatta ttatgcgtgg cggcaaaaaa ccgaattatc atgccgatga tatcgccgca
     1801 gcctgcgata cgctgcacga gtttgattta cctgaacatc tggtggtgga tttcagccac
     1861 ggtaactgcc agaagcagca ccgtcgccag ttagaagttt gtgaggatat ttgtcagcaa
     1921 atccgcaatg gctctacggc gattgctgga attatggcgg aaagtttcct gcgcgaagga
     1981 acgcaaaaaa tcgtcggcgg tcagccgctc acttacggtc aatcgattac cgacccgtgt
     2041 ctgggctggg aagataccga acgcctggtc gaaaaactcg cctctgcggt tgatacccgc
     2101 ttctgaatgc gtgcccattc ctgacggaat gggcatttct gcgcaacttg ttgtcttctc
     2161 aacacattac tgcttgctct ggcccgccag aatattgata ataagaatca ttgttatatt
     2221 aattattatt aatttttatg cgttatacgg atagcagaaa actcacgcct gaaacggatg
     2281 ccaatcacaa gaccgcttcc ccgcagccca ttcggcgaat taccagccag acactgttag
     2341 gtccggatgg caaactgatt atcgatcatg acgggcaaga atatctgctc cgtaaaactc
     2401 aggctggcaa gctgctgttg accaagtagc ctttaactcg agcagctgac ttccagccgt
     2461 ttaccccagt caggtggacg actgacatag tcatcatctc tgtcgctgaa aggatttcgc
     2521 aacgcctcat gcaggcggtg caattccgtc atatcaccct tttctgccgc ttcaatcgcc
     2581 cgttgcgcca accagttgcg caacaccaga gctgggttaa cgctttgcat cagttgctga
     2641 cgctcactat cgctaacctc gtcttgttgc aaacgcctcc gataacgggc aaaccagtca
     2701 tcaaatgccg cacgatcaat aaactcatca cgtagcggtg acgccgcgct gtgctgctcg
     2761 gtcagactca gcatgcggaa tgtgcgggta taatcgctgc gctctcgcgc catcagactg
     2821 aataattcat tcagtagcgc gttatcctct ttttgctccg tcatgaagcc cagtttctgc
     2881 cgcatccgtt gtccataatg cgtcaacaaa acctgctgat agctgtccag ggcctcattc
     2941 agggcatcta cggcaacaaa tggtgacaat gtctgcgcca gacgctgtaa attccacaac
     3001 gcgacagcag gttgattatc aaagctataa cgcccttgat gatccgagtg attacaaata
     3061 aaaccgggtt cgtaatcatc aagaaaacca aacggcccgt aatcaagcgt cagccccagc
     3121 agcgacatgt tgtcggtatt catcacccca tgagcaaagc cgaccgtctg ccattgggca
     3181 attaacgatg cggtacgtgc gacaacatcg ctaaaccaga gacggtattt gtcctcatca
     3241 tctgcaagat gtgaccagta atgacgaatg gcaaagtcag ccaactgacg aaccttttcc
     3301 ggctcgcggc gatagtaaaa atgttcgaaa tgaccaaagc gcagatgact tggtgccaca
     3361 cgcatcagca tcgcgcctga ctccaccgtt tcccgataca ctggcgaatc gctggtgacg
     3421 atacttaacg cgcgggtcgt cggaatgccc agataatgca tcgcctcact ggcgagactt
     3481 tctcgtatcg tcgaacgtaa aaccgcccgt ccatcaccca ttcgcgaata aggcgtcagg
     3541 ccagcacctt tcagatgcca gtccattgta gtgccatcgg ccagctgttg ttcgccgagt
     3601 aaaatgccgc gcccatcacc cagttggccc gcccagacgc cgaactgatg accactgtaa
     3661 acctgcgcca gtggtgacat accaggcagt agggtttcgc cgccccagac acctgcgcca
     3721 tttttaaaca gcgacgatgg aatactcagc gtgttagcca gttcggcatt atgccaaatc
     3781 agccgggcct tatttaaagg cgtaggggaa agtgctgtat aggtttctgg caattcatcg
     3841 caccagcggg taataaaaga cagggtcata gatcctcctg tttgatagtg tagacggtta
     3901 ctctcgtctt aaacaccagc aaacaggagg gttatcgctg aaccaacgtc gttatctgat
     3961 ttacaggaac ggcaggccac aggcatccct ggagagcatg gaaatcaaag ggggtaatct
     4021 gtgccattat ttctggcgta tcaatgcccc ccgcgatgat gcaattgcaa catggggaaa
     4081 tttgcgcctg gatcgcacga ataaacggtt cgaaggagcg atgcgtgatt tgttgctgaa
     4141 taaaactttt atccagcatg acgcgggtga aaagaccatc aaaaaccgct ttcattgtgc
     4201 tattgcctgc gcccaaatta cctaacacaa ggggatacat ttgcgataag gaaaaaagat
     4261 cgcgattatc ttttccttca tcgagatgcg ggtaattctc attaatcaac agttcaataa
     4321 acggatattt taatagttcg cccgcgtaat tatccctgtc taataataaa gtagccactt
     4381 gtggggttaa attaagccag gcaaagagtt tatgttgaat aaaaaagtgt tggcatgatt
     4441 ttagcaattc caactgctca gaaaataatt gccaatgttg ctcctcggta agttgcgcta
     4501 taacccgact cgtcgggata cgaaccgtac catcttcact ggagaaatgg gtaattaact
     4561 caacgccgac aaggtcttgc tggttatctc ttatcggcag gaaatagcaa tcagaatgat
     4621 aaagattctc caaaaaaatc ttcatggtaa ccgtccctct cgaaggatgt ttttcagtat
     4681 ccggctaaaa gggatgaggc cataagacat aacaattaca gaaggagtaa ctttcatttg
     4741 ttccatgtta accacttttt caggggtcct tttattagat tatcctgatt ataaacgaat
     4801 aatccattta cggaattttt gtctgtaaaa tactactgta ttcaggagta aatggacgga
     4861 gatgtatcat cgccgtccat ttttcgacat actagattcg tctcgcctgc cagaaatttt
     4921 tctgccaata aacattatcg agtgaggaac gcatcactcc cttgctggta gaggcgtgga
     4981 taaattggtt gttggtatcg taaataccta catgcaaacc attttgtccg gagcccgttt
     5041 tgaaaaagac caggtcacca ggcagcaact cgtctttatc aatttgcgtg ccgatagagg
     5101 cttgttcttt ggtttcacgg ggcagctgca aatcgaaacg atcgcgcatc gtcacaacca
     5161 caaaccccga acagtccaca ccgcgccgcg tcatgccacc ataacgatac ggcgtgccat
     5221 gccagctctg tagctggtcg ttcaaaccgg caataacggt aatcgaatca gaaagtctgg
     5281 catttggcgg cggtgcttta tggtggctac acccggccag aaacagtgct gtgatcaaaa
     5341 taaggcagaa acgcattccg tacggttcct ctgtttttta ttcttgcatt aatttagcgt
     5401 cgtaattacc cgattttcaa gatactaatg aaatcagatg gtcgaaatca gcattctgtg
     5461 accttcgata tccagacggc gaaaattcat cccataggcc tgcgccagat ttggcggcgt
     5521 gagcacctct tccctgcgtc cactggccag catttttcca ccttttagca accacgcccg
     5581 atgcgcatga cgcaatgtat ggttgagatc gtgactgctc atcacaatcg ccagtccttg
     5641 ctgacacagc gcgctcagaa ttttgtctaa tgcactttgt tgcgcaacat caagactgtt
     5701 cataggctca tcaagaagta gtaattggcc tgcgggattg gcttgtggtg tgatttgcag
     5761 caccaccgca gcaagacgta cgcgttgcca ttcgccgccg gaaagttgat tggtgctacg
     5821 tccgagtttg tcatcaagag ccagcgcccc tgcgacatca ttcagtagtt cggtacgcgt
     5881 tttatcgtgc tgatgcagtg tcaggtagtg ccagaccggc attgcaaacg gcggcgtctg
     5941 ctgttgtgaa agataggcgc gatgcagcgc gagttttgtt gcggaccatg cttccagtgg
     6001 ttgccccgcg aactgaatgc ttcccttacc gctggtcatt ccggccattc gcgccagtaa
     6061 ggtactctta cccgcgccgt tcggccccac caggtgcagg atctccccag cccgaacctc
     6121 gccagaaagc ggccccaggc gggtagattc cgcaacatcc tgtaactgca tcacaataga
     6181 cattattttg ccaacgccag tttaatgctt tccatcacaa tgggatcttc cggcgtcata
     6241 tccggggaaa aacgctggat gaccaatccg tccctgccaa ctaaaaattt ctcaaaattc
     6301 cataaaatat catcagggta cagcggtgca cgacctttgc tgaccatacg ggcatagaat
     6361 ccgctctctt ccggcgcgac tgcggtcggc gctgcggcaa tcaatttttg atacagcgga
     6421 tggcgtcctt cgccattaac ttcaatctta ctgaacatcg ggaacgtcac cccccatgtg
     6481 gtggtacagt aagttttaat ctcttcatcg ctgcccggtt cttgttccag aaactggttg
     6541 cacgggaatc ccagtaccac aaaaccacga tcggcccagg ctttctgaat attctccaac
     6601 tgctcatatt gcggcgttaa gccacacttt gaggcgacat tgacaatcaa cagcacatta
     6661 ccggcatact tctccagcgt ggtcacttca ccgtcgatat ctttcactac ggtcgtcaga
     6721 atggaatctt gcatcgtttc tcctgggtgt ggtcagtaaa aatcttagct tttaatcata
     6781 gaccgtcttt ttgcggctaa cgtcctgctt ttaacaataa ccagataaac accggcgcac
     6841 ccaacgttgc ggtgaccacg ccaataggca gctctgcggc agctaatgcc aggcgcgcta
     6901 caatatcggc cagcagcaat gcgctcgccc ctgccagcgc gcagccggga agtaatacgc
     6961 gatgatcggt taaaccacac agccggagaa tatgtgggat caccagacca ataaagccga
     7021 tagcacccgc cagcgccaca ctgacgccaa ccatccagcc ggtcgctgcc accaacacat
     7081 tgcgccagaa ccacaggggt aaacccagtt gccgcgccga gatctcgcca agtgctaaca
     7141 tattcattgg cctggactga caacagatcc acaacaacac ggggatcaat gccagcatca
     7201 gccagctttg ccgccagtct acgccgccaa aaccgcccat catccagtac atcagctgac
     7261 gtaaatcaac agaggtggaa aagtagatag cccacgtcat tagtgcgcta cagataatcc
     7321 ctaatgcaac gccagccagc aataaccgac tggtcgaaag atgacgacgg gcgaaacgta
     7381 agagtattaa agtgatgata agcgcgccag caatcgcaca cagccccagc gcccagttgg
     7441 ggagttgccc ttgcccaagc aataccgcgg cgataagccc cacgcctgcg ccattagaga
     7501 cgccaagtag tccaggttct gccagaggat tttcaaacaa cgcctgcatt acagcgccgg
     7561 atatagccag cgccgcacca accagcaata cagccagcgt acgtggcagg cgaatttgcc
     7621 agacgaacag ttcgccacga ggagtaaacc agtcacctgg cgagatccat tgttcaccgg
     7681 cgcaaaggct taagagaagc gccagcagca tcaaaactga caggcataat aaccagcgaa
     7741 tattttgtcg ctgttgttgg cgggcaagtg tcagcatggt atccgttctg ctgaagtgtc
     7801 atggcgttga ttttacggtg actcttcgac agtgaaaaga aaaaaggccg cagagcggcc
     7861 tttttagtta gatcagatta ctcgtctttg ggcgaagcgt tttcgacccg gctttttaac
     7921 ttctgcccgg gtctgaaggt caccacgcgc cgtgctgtaa tgggaatatc ctcgcccgtt
     7981 ttcgggttac gtcccgggcg ttgattctta tcacgcagat cgaagttacc aaaaccagag
     8041 agtttcacct gttcgccgtt ttccagagcg cgacggatct cttcgaaaaa cagttcaacc
     8101 agttctttgg catcccgctt gctaagccca agcttatcaa acagatattc tgacatttca
     8161 gcttttgtaa gcgccatagg ttcaatccct caatgatgcc tggaatcgct cttttaatgc
     8221 ctctacacat ttggcgacgg tagcggcaat ctcctcttct tcgagtgtac ggctggtatc
     8281 ttgcaggatc aggcttatgg cgaggctctt atacccctcc gcaacaccct taccgcggta
     8341 cacgtcaaat aagtttacgc caactacctg atttacgcca actttcttac attcggataa
     8401 aatatccgct gcgggaacgt tttctgcgac caccaccgcg atgtcacgac ggttcgccgg
     8461 gaagcgagaa atctcgcgcg cctgaggcac cacgcggtct gcgagcttgt tccactccag
     8521 ttcgaacacc agagtgcgac cgttaagatc cagtttacgt tccagttcag gatgaacaac
     8581 cccaacaaaa ccaatacgtt cacctttcag ataaatcgct gcggattgcc ccggatgcag
     8641 tgccggattc gcttctgcac ggaactcaac ctcattcagt ttaccggtca ggtcgagaac
     8701 ggattcaaga tcgcctttca aatcatagaa atcaacggtc tcttttgcca ggttccagtg
     8761 ctcttcgtaa cggttaccgc aaatcacacc ggctaacatc agatcctgac gaatgcccaa
     8821 cggtgcctga gtatctggta cgaaacgcag accgctttcg aaaatgcgca cacggttctg
     8881 ctgacggttc tggttgtaca ccacggttgc cagcaggccg gtccacagag aaagacgcat
     8941 tgctgacatt tcaacagaga tcgggcttgg cagcagtaag gcttcaacgc ctggatggat
     9001 catctgctgc actttcggat caacgaagct gtaggtgatc acttcctgat agcctttgtc
     9061 gttgagcagc gttttcacgc gcttgagcga caggtcagct tcacggtgag tacccataat
     9121 caggcttgcc tgtaccggct catccgggat gttgttgtag ccgtaaacac gcgccacttc
     9181 ttcaaccaga tcttcttcaa tctccatgtc gaaacgccag ctcggcgcaa cggcctgcca
     9241 ttcgtctttg ccttcggtca cttcgcagcc gagacgacgc agaatgtcag taacctgctc
     9301 atcggcaata tgatggccaa tcaggcgatc cagtttgctg cgacgcaaag tgatggttgc
     9361 acgcttcggc agcgttgctt cgttgctgat atcaattacc ggaccagcct caccaccgca
     9421 gatgtcgatc agcagacggg tcgcacgttc catcgctttg tgctgcagtg ccggatcaac
     9481 gccacgctca taacggtgag acgcatcagt atgcaggcca tgacgacgag cacgaccggt
     9541 gattgatagc gggctgaaga aagcacattc cagcagaacg ttttgcgttt cgtcattcac
     9601 accagagtgt tcgccaccaa agatgccgcc catcgccagc gccttgttgt ggtcggcgat
     9661 gaccagggtg tcagcgttca gcttcgcttc ggtaccgtcg agcagtacca gcgtttcgcc
     9721 ctctttcgcc atccgcacca caatgccgcc ttcaatgcga tctttatcga aagcgtgcat
     9781 cggctggccc agttcgagca gcacatagtt ggtgacgtca acaactgcat cgatagaacg
     9841 gatcccgcaa cgacgaagtt tttctttcat ccacaacgga gttggcgctt taacgttaat
     9901 gccttttacc acacggccaa gatagcgcgg acaagcttcc ggcgcttcga ctgcaatcgg
     9961 cagcgtgtcg tcgatggtcg caccaaccgg aacgatttcc ggttcaacca gcggcagctg
    10021 gttcagcacg gcaacgtcac gcgcaacacc aatgatacct aagcagtcgg cacggtttgg
    10081 cgttacgcta atttcgatgg tgttgtcatc gagtttcagg tattcacgaa tgtcggtgcc
    10141 aattggcgca tccgcaggca gttcgataat accgctgtga tcgtcagaaa ttcccagctc
    10201 agagaaagag cacagcatcc cttcagacgg ttcgccacgc agtttcgccg ctttaatttt
    10261 gaaatcgccc ggcagaacag caccaatggt cgctaccgcc acacgcaggc cctgacggca
    10321 gtttggcgca ccgcagacga tgtccagcag gcgatcgccg ccgacattca cttttgtcac
    10381 acgcagtttg tcagcgttcg gatgctgcgc acactcaacc acttcaccaa cgaccacgcc
    10441 gtggaagcta ccggcaaccg gttctacacc gtcaacttcc aggcccgcca tagtgatttg
    10501 atttgccagc gcatcgctat caatcgccgg gttcacccat tcgcgtaacc acagttcact
    10561 gaatttcata atctactcct gccttattta aactgtttga ggaaacgcag atcgttttcg
    10621 aagaatgaac gcaggtcggt gacgctgtaa cgcaacatgg tcagacgctc catccccatc
    10681 ccgaaggcga aaccagagta aacttccggg tcgatgccaa cgttacgcag cacgttcgga
    10741 tgcaccatcc cgcagcccag tacttccagc catttaccgt ttttacccat gacgtccact
    10801 tctgcagaag gttcggtaaa cgggaaatag gaaggacgga agcggatctg caaatcttcc
    10861 tcaaagaagt tacgcaggaa gtcgtgcagc gtgcctttca ggttggtaaa gctgatgttg
    10921 gtatcaacaa tcagaccttc catctgatgg aacatcggcg tgtgagtctg gtcgtagtcg
    10981 ttacgataaa cgcggccagg cgcgatgata cgaatcggtg gctgctgagc tttcatggtg
    11041 cggatctgta cgccagaggt ctgggtacgc agcaggcggg tagcgtcaaa ccagaaagtg
    11101 tcgtggtcag cgcgcgccgg gtggtgacca ggaatgttca gagcatcgaa gttatgataa
    11161 tcgtcttcga tttccggccc ggttgccacg gtaaagccaa gctcaccgaa gaaactttcg
    11221 atacggtcga tggtacgggt caccggatgc agaccgccgt tttcaatacg acgaccaggc
    11281 agggagacat caatcgtttc cgccgccaga cgcgcattca gcgctgcgct ttccagttcc
    11341 gctttacgcg tattcagcgc ctgctgaacc tgctctttcg cttcgttgat aaccgcaccg
    11401 gctgccgggc gttcttctgg cggcagctca cgcagggtcg tcatctgaag ggttaagtgc
    11461 ccttttttac ccaaatattc gacgcgcaca ttgtctaacg cggcaacatc tgacgcctgg
    11521 ctaatggccg ccttcgcact ggcaaccagt tctgcgagat gtgacatggt tttcctcatt
    11581 gtgtctgtgg tgacactggt tcgttggact taattttttc aaaacgcgca tacaaaaaaa
    11641 gcctccactg ggaggctttc aggcgctgtt ttccgtttct cttctcacgc gctagcctcc
    11701 tggagtcagg tgctaaagta aaaaaagaag cggaaaatag cagcattcat tgcttgcgtt
    11761 accttttggt acttttcaaa agacctttat tgaaaaggct acggcgataa aagtcaatgt
    11821 tttgatggcg ttgaaacgaa aagagggaga ctagctccct ctttcaactg gcttatgcca
    11881 gagctgcttt cgctttttca accagagcgg tgaacgctac tttgtcgaat actgcgatat
    11941 cagccaggat cttacggtcg atttcaacag aggctttttt caggccattg atgaatttgc
    12001 tgtaagaaat accgttctga cgtgctgctg cgttgatacg cgcaatccac agttgacgga
    12061 actgacgctt acgttgacga cggtcacggt aagcatactg accagctttg ataacagcct
    12121 ggaaggcaac gcggtatacg cgagaacgcg caccgtagta gcctttagct tgtttcaaaa
    12181 ttttcttgtg acgtgcgcgt gcaataacac cacgttttac gcgagccata tgtgctctcc
    12241 tgtatctata ttctaattaa aaagttaaaa aacgttaacg gcttatgcgt acggcaggca
    12301 cgcgattacc aggcccagat cgcctttgga aaccatggct ttcggacgca ggtgacgttt
    12361 acgtttggtc gcttttttgg tcagaatgtg acgcaggtta gcgtgcttgt gcttaaaacc
    12421 acctttaccg gtttttttga agcgcttagc agcaccgcgt acggtcttaa tttttggcat
    12481 tttgataact tccacttcgc attgttaata aacgaaacaa aggcgaacaa tgcctgtgaa
    12541 gcccaaaggc tccacagaca gtgctacttg aaggccttac tgtttcttct taggagcgag
    12601 caccatgatc atctggcggc cttcgatctt cgttgggaag gattcgacca ctgccagttc
    12661 ttgcaaatcg tctttcacgc gattaagcac ttccataccg atttgctggt gcgccatctc
    12721 acgaccgcgg aaacgcagcg tgattttggc tttatcaccc tcttcgagaa agcgaatcag
    12781 gctgcggagt tttacctgat agtcgccttc atctgtacca ggacggaatt taatttcctt
    12841 aacctggata actttttgct ttttcttctg ttccttagaa gacttgctct tttcatagag
    12901 gaatttgccg taatccatta tacgacaaac cggcggctcg gcgttagggc tgatctcgac
    12961 taagtctact ccggcttctt ctgctttctc cagagcttct ctcagactca caataccaag
    13021 ctgctcgcct tccagacctg ttaagcgaac ttcctgggcg cgaatttcgc cattgatacg
    13081 gttagggcgc gccgtttgaa ctcgttttcc gcctttaata ccttattcct ccaattgttt
    13141 aagactgcgg ctgcgaatct cttgttgcag cttctcgatc acttcattta cgtccatgct
    13201 tcccaggtct ttaccacggc gggtgcgaac ggcaactttg cctgattcca cctctttatc
    13261 accacagacc agcatatacg ggacgcgacg caaagtgtgc tcgcggattt taaagccaat
    13321 cttctcattt ctcaagtctg ctttaacacg aatgcccgca tttgatagtt tttgcgtcaa
    13381 ttcgttaacg tattcagact gtgaatcggt aatattcatg ataacaacct gaaccggcgc
    13441 aagccaggtc gggaagaaac cagcgaattc ttcggtcagg ataccgatga aacgttccat
    13501 cgaccccaga attgcgcggt gaatcattac cggtacctta cgctcgttgt cttcgcccac
    13561 ataggaggcg ctcagacgag acggcaagga gaagtccagc tgtactgtac cgcactgcca
    13621 tgcacgatcg aggcagtcat acagggtaaa ttcaattttc ggaccgtaga aagcgccttc
    13681 acccagttga tattcaaacg ggatgttgtt ttcttccagc gcaaccgcca ggtccgcctc
    13741 agcacgatcc cacatttcgt cgctgccaat acgtttttca ggacgagtgg agagtttgac
    13801 gacgatcttc tcgaagccaa aagtgctgta catatcatag actaaacgga tacatccgtt
    13861 aacttcatcg cgaatttgtt cttcagtaca gaagatatgc gcgtcatcct gggtaaatcc
    13921 acgtacgcgc atcaggccat gcagcgaacc tgacggctcg ttacggtggc agctaccaaa
    13981 ctcggccata cgcagcggca aatcgcgata cgacttcagc ccctggttga aaatttgtac
    14041 gtgacccggg cagttcatcg gcttaatgca gtattcacgg ttctcagaag acgtggtgaa
    14101 cattgcatct ttgtagttgt cccagtgacc ggttttttcc cacagaacac ggtccatcat
    14161 gaacggacct ttaacttcct gatactggta ctctttcagt ttagaacgaa caaacacttc
    14221 cagttcacgg aagatggtcc agccatcgtt gtgccagaat accatacccg gtgcttcttc
    14281 ctgcatatgg tacaggtcga gctgtttacc gattttacgg tggtcgcgtt tcgcggcttc
    14341 ttccaggcgc tgcaggtaag cgttaagcgc ttttttgtct gcccacgccg taccgtaaat
    14401 acgttgcaac attttgttgt tgctgtcgcc acgccagtaa gcccctgccg ttttcattag
    14461 tttgaaatga tggcagaaac gcatgttcgg tacgtgcgga ccgcggcaca tatcgacata
    14521 ttcttcatgg aagtacagac ctggcttgtc atcatgggcg atgttttcgt caagaatgga
    14581 gactttgtag ctctccccac ggttggcgaa agtttcacgc gcttcgtgcc agctgacttt
    14641 cttcttaatg acgtcgtagt ttttctcagc aagctcatgc atccgcttct cgagtgcttc
    14701 gacatcttcc tgggttaacg tgcggtcaag atcaacgtcg taataaaaac cgttgtcaat
    14761 aaccgggccg attgccattt tggtatgcgg ccaaagttgt ttaatcgcgt gccctaacag
    14821 gtgcgcacag gagtgacgaa tgatctccag accttcttcg tctttggcgg taatgatcga
    14881 cagttgtgcg tcgttttcaa tcagatcgca agcatcaacc agttcgccat taacgcgccc
    14941 tgcgatacag gctttcgcca gacctggacc aatgtccagc gcaacatcca tggggcttac
    15001 agcgtggtcg taatggcgtt ggctgccatc aggaagagtt ataacaggca ttttatatcc
    15061 ttatttgcag tggtgaccca cacgaaagat cacatacaaa gaaaaatttg tttattaaca
    15121 gttcattgcg aaaccatcta gccaacaaat gctaaattgg ttcgcaatca ggtacacaaa
    15181 tgaaagacat taacctctca ccttccaccc gcttgaacga tgttaacact aaaaaaaggg
    15241 agattgtacc tttccgtttc acattgattc gattcgtaat tcgtttgtag tgagtacacc
    15301 agcaaaacgc ttaaagaacc actgataaca tcacggagcg tctgaaaggt ttactgcgag
    15361 cggatttgca gcagcataaa ctgaatccag caaagttcgt tgcgtgattt ggcggtacta
    15421 tttaaacgat cataagatta atgacgaagt ggtcatatca caatgataaa agtgacacaa
    15481 ttcttatagc aatttttcgt gcacatttcg ttctggcgat aataattaat catcatcctc
    15541 aaaacctcca gacatatata aggcgaaaag attatgagtc aaaacgacat tattatcaga
    15601 actcattata agtctcctca tagaatgcac atcgatagcg acataccaac gccttcatca
    15661 gagcctatta atcaatttgc gcgccaactc atcaccctac ttgatacctc tgacttaagt
    15721 tcgatgctgt catactgtgt tactcaggaa tttaccgcaa actgtcgaaa aatatcacaa
    15781 aattgttatt ccactgccct ttttaccatt aactttgcca cttcacccat ccatgcagaa
    15841 aatatactca ttacattaca ctataaaaaa gaaatcattt ccttacttct ggaaaccacg
    15901 cccattaaag ctaaccattt gcgaagcata ctggattata ttgaacagga acagtcaact
    15961 gccgaaaaac gtaaccattg catgaagctg tcaaaaaaaa tccatagaga aaaaactata
    16021 caaccaacag taaacctcaa tggtagtgca tttttttcgc aatctccttc tgacgctatt
    16081 ttttgtcgcc atctgtcatt gcaatacgca cttgattcac tgagaaatgg aaaaggcaaa
    16141 gtcaatctga ttaaacatta ctcctccgtt gaatccatac agcagcatgt tcccttagtc
    16201 cgggacgcgg agttcagatc attacttcgc catcctcctg cagggagtcg cgttatcgcg
    16261 agtaaagatt ttggcttcgc tttagatatt ttcttctgtc gaatgatggc aaacaatgtc
    16321 agtcatatgt ccgcgatttt atatatagac aatcatactt tgtcagtaag gctacgaata
    16381 aagcagtcag cgtatgggca attaaattat gttgtgtccg tttacgaccc gaacgatacc
    16441 aacgttgccg tcagaggcac ccacaggaca gcacggggct ttctctcgct cgataaattc
    16501 atcagttcag gtcccgatgc tcagacctgg gctgatatgt atgttcgcaa ctgtgcaatt
    16561 gcttttctgc ccctattacc tgagggagtt ccaggggcta ttttcgcggg tattgcatca
    16621 cgaatgccat ttgcccctat acatccatcg gcaatgttgt taataatggc cacaggccag
    16681 actcaacagc ttattacatt attcaaacag ttacccatac tccctgaaaa agaaatcatt
    16741 gaaataataa ctgcgcagaa tagcgttggt acacctgcat tatttttggc tatgatgaac
    16801 ggacatactg acaacgtgaa aatatttatg caagaaattc agtcactggt agataatcat
    16861 atcattcatg aagataatct ggttaaatta ctgcaaacta aaagtgctaa cgaaacacct
    16921 ggactctata tctccatgtt gtatggattc gatgaaataa tcgatatctt tctgaatgca
    16981 ttaaccactc caataacaca agagctttta agcaaaaaaa tggtgatgga tattttagca
    17041 atgaaaacac gtgatggtga gccaggatta tatgccgcaa tggaaaataa tcaccctttg
    17101 tgtgtcacac ggttcctctc taaagtttat ggaatcgctg ttaaatataa cctcagcaaa
    17161 attaacatca tggatttatt aaaaggcgca acagcacatg gaacccctgc tttatacatc
    17221 gccatgagta agggtaataa agacgtcgtg ttatcttata tatcaacgct gggtactttt
    17281 gcaaaaaaat attcttttag tcaatgtcag ttattcacat tgttggccgc taaaaatcat
    17341 gacaacatgt cagctgttca tatagccatt catcataatc attataaaac tgtagaaaca
    17401 tattatgctg ctataaacgt aatcagccaa agcctgagtt ttagtgctga tgagctaaag
    17461 acgtatttat aaccagatat ttatatatcg atacataatt ttattttttt cataaaccgc
    17521 aaaaacagtg atcaggtgta caacgccacc cgacggctgt aataacaaaa aatcccttga
    17581 tgcctgtccc ttttgttaca ctccgttatc acgcacaaga gatatgcagg acactggtat
    17641 gccgactaaa cgctttgata aaaaacactg gaagatggtg gtggtgctac tggcaatctg
    17701 tggcgctatg ttgttgctac gttgggcagc aatgatttgg ggctgagcag tgacaaacga
    17761 aaacagccag accgcatact acggtccggc agataatgtt acatgctgta gcccagcgat
    17821 aaggttgtcc gacgatcggt atgttccggt gcagactctg gaggttcaga gttccatgtg
    17881 acgttgtaag ccaccttcag tccaaaatgt tcattaatag caacatttaa tgcgctttca
    17941 gagttcagcg ttgtgtcttc cgcgccaaag acggaaacac cctgcgtaaa tttaacgttg
    18001 tcagtcaact gccatgcata agccccggag gcataaccca gcggctgggt ttcactggca
    18061 ttgtcggtat atttgtcgta acgcacacct ggaccgaatt caaagcggaa actgtgtacc
    18121 gggccattca aaaactgacg accataaccc gcggtcaaca catcgcgctc tcgatagccg
    18181 ttataacggt ctgtcagcca gcttgcctga ccaaataaat agtcataatc agttaaatta
    18241 aaacggctac gcccgcccgc cgcatatttt tctgaagaac gctcatcatt agaagaagta
    18301 ttactggcgt tcccccacag cgaccaggca gtggtttgtc cataccaggt catggtggtg
    18361 tcagccgtaa gtgaggagct tttcgtattg cctgattgtg caagatatcc tgcgttcaga
    18421 ttaccttcga aaggtttttt agcgctggca ggatcgtcca tgacagtaaa aacggaatca
    18481 tcggcagctg cattcagtga cgcaaacatg ccccccgcca acataacgat ggcaggaact
    18541 gtcttcaaaa gcttcattta tcaagagtcc gtacaacaaa aaaagagacc atcgcggtcc
    18601 cggaaacttt cttaaggatc aaagattagc gtccctggaa aggtaacgaa ttataaaaag
    18661 gcgcgaataa cttagcaatg tattcttatt tcattttttg aataagcatg tggcgaaaac
    18721 agatttttat ttatatatat ttatctgcaa aattttaaat aaagctctaa taaatcatat
    18781 tgttaatttc ttcactttcc gctgattcgg tgccagactg aaatcagcct ataggaggaa
    18841 atgatggtac gtatctatac gttgacactt gcgccctctc tcgatagcgc aacaattacc
    18901 ccgcaaattt atcccgaagg aaagctgcgc tgtaccgcac cggtattcga acccggaggc
    18961 ggcggcatca acgtcgcccg cgccattgcc catcttggag gcagtgccac agcgatcttc
    19021 ccggcgggtg gtgcgaccgg cgaacatctg gtttcactgt tggcggatga aaatgtcccc
    19081 gtcgctactg tagaagccaa agactggacc cggcagaatt tacacgtaca tgtggaagca
    19141 agcggtgagc agtatcgttt tgtcatgcca ggcgcggcat taagtgaaga tgagtttcgc
    19201 cagcttgaag agcaagttct ggaaattgaa tccggtgcta tcctggtcat aagcggaagc
    19261 ctgccgccag gtgtgaagct ggaaaaatta acccaactga tttccgctgc gcaaaaacaa
    19321 gggattcgct gcatcgtcga cagttctggc gaagcgttaa gtgcagcact ggcgattggt
    19381 aatatcgagt tggttaagcc taaccaaaaa gaactcagtg cgctagtgaa tcgcgaactc
    19441 acccagccag acgatgtccg caaagccgcg caggaaatcg ttaatagcgg caaggccaaa
    19501 cgagttgtcg tttccctggg tccacaaggg gcgttgggcg ttgatagtga aaactgcatt
    19561 caggttgtgc caccaccggt gaaaagccag agcaccgttg gcgctggtga cagcatggtc
    19621 ggcgcgatga cactgaaact ggcagaaaat gcctctcttg aagagatggt ccgttttggc
    19681 gtagctgcgg ggagtgcagc cacactcaat cagggaacac gcctgtgctc ccatgacgat
    19741 acacaaaaaa tttacgctta cctttcccgc taactgaaac attccccctg cattggggga
    19801 atcaccacca acctgtcggc aacgcgtttc tccgactatg ctcaaaagtc atgtgataac
    19861 aaaggggtga actatggcca gtggcgatct tgtccgttat gtcataaccg tcatgttgca
    19921 cgaagataca ttgactgaaa ttaacgagtt gaataattac ctgactcgcg acggtttttt
    19981 gctcaccatg acggatgatg atggaaatat ccatgagctg gggactaaca cttttggact
    20041 tatcagtacc caaagtgaag aagaaattag agaactggtt tcggggctta cccaaagtgc
    20101 aaccggcaaa gatcctgaaa tcaccatcac gacctgggag gaatggaata gcaacagaaa
    20161 ataaatggtt tttgggcaat aatcagtctg tggtgtgcgt tagctcgtgt ttttacaccg
    20221 cattcttgcg ctaaccttat gatctggcag acaacatggg agagacatca tgtggcaggc
    20281 aatcagtcgt cttttgagcg agcagttagg tgaaggcgaa atcgaactgc gtaatgaact
    20341 gcctggcgga gaagtccatg ccgcatggca tttgcgctat gcaggacgtg actttttcgt
    20401 caaatgtgat gaaagggaac tgcttcccgg ttttaccgcc gaagccgacc aactggagtt
    20461 actgtcgcgt agtaaaaccg tcaccgtgcc taaggtttgg gcagttggcg ctgaccgtga
    20521 ctacagtttt ctggtgatgg actatctccc acctcgaccg ctggatgcgc atagtgcatt
    20581 tattcttggt cagcaaattg cgcgtttaca tcaatggagc gaccaaccac aatttggcct
    20641 cgatttcgat aacgcgctct ccacaactcc acagcccaac acctggcaac gtcgctggtc
    20701 aacttttttt gctgaacaac ggattggctg gcagctggaa ctggcggcag aaaaagggat
    20761 cgctttcggc aatatcgatg ccatcgtcga gcatattcag cagcgtctcg cctcgcatca
    20821 accgcagcct tctctgttgc acggcgattt atggtccggc aactgtgcgc tgggtccgga
    20881 tggcccgtac attttcgacc cggcctgcta ctggggtgac cgagagtgcg acctggcgat
    20941 gttaccgctg catactgaac agccgccaca aatctatgac ggctatcagt cagtatcccc
    21001 gctacctgcc gatttccttg aacgtcaacc ggtttaccaa ctctacacgc tgttaaatcg
    21061 tgcaaggtta tttggcggtc agcatttggt tattgctcag cagtcactgg atagattatt
    21121 agcagcataa tatggggtga ggataatggc cgctccgtgc ggccttttga ttaaataaac
    21181 cccagcagag aaaagaacac ataacctgca gcaatacaaa taaccggcag gatatacagc
    21241 gagaaaaact gcaggaaaat agtatggtgc ggcacaacaa tacgtgactc aatttgttca
    21301 cgcgttagcc cctcttcccc tttggctttt tccagaatga gttgatcttc aacaccttcc
    21361 cgcaagaagc gcgcctggcg actcatccgg gcaccggaat cctgcaacgc cagtccgaca
    21421 aaaatcagga tgaaaatcac ccagaacata acgttcacgc caccattaaa attgggcgtc
    21481 ggggagttat accagaacag attcaaaaaa ggcgtattcg cctgcatcat atcgatcatg
    21541 acatgagtaa agtcgagcat gaccgcatta atgccttcct ggttttcctg ccgggtattc
    21601 ataaatttaa gcaaagaaat caatgtagag atcaatgcag gtataaaaat cacccaaccc
    21661 aaaatccttt tcaaaacagc aatgcgtcca gcttgttgat acgtcatgag ttctccttga
    21721 ttaagacgcg tcgtttcact tagtttacct gtagatatct gttttcgccc attctttaaa
    21781 ggcgatatga taggcgctta atcataagca cggcttaata ccttacacat aatgctctaa
    21841 aggagaggtt gtaatgtcaa ccccgcgtca gattcttgct gcaatttttg atatggatgg
    21901 attacttatc gactcagaac ctttatggga tcgagccgaa ctggatgtga tggcaagcct
    21961 gggggtggat atctcccgtc gtaacgagct gccggacact ttaggtttac gcatcgatat
    22021 ggtggtcgat ctttggtacg cccggcaacc ctggaatggg ccaagccgtc aggaagtagt
    22081 agaacgggtt attgctcgtg ccatttcact ggttgaagag acacgcccat tattgccagg
    22141 cgtgcgtgaa gccgttgcgt tatgcaaaga acaaggttta ttggtgggac tggcctccgc
    22201 gtcaccacta catatgctgg aaaaagtgtt gaccatgttt gacttacgcg acagtttcga
    22261 tgccctcgcc tcggctgaaa aactgcctta cagcaagccg catccgcaag tatatctcga
    22321 ctgcgcagca aaactgggcg ttgacccact gacctgcgtg gcgctggaag actcggtaaa
    22381 tggcatgatc gcttctaaag cagcccgcat gcgttccatc gtcgttcctg cgccagaagc
    22441 gcaaaatgat ccacgttttg tattagcaaa cgtcaaactc tcatcgctga cagaactcac
    22501 cgcaaaagac cttctcggtt aatgaccagg ggcagtgatc agactgctcc tggttcttta
    22561 tctgaatttg cattcaactg acggattaat cgtcaattta agagaaagag ttacaccgtc
    22621 accacttccg cgcactgtat aaaaatccta tactgtacgt atcgacagtt tagtgagttt
    22681 tatcatgacg gcggaaggtc accttctctt ttctattgct tgtgcggtat ttgccaaaaa
    22741 tgccgagctg acgcccgtgc tggcacaggg tgactggtgg catattgtcc cttccgcaat
    22801 cctgacgtgt ttgttaccgg acatcgatca cccaaagtcg tttcttgggc agcgattaaa
    22861 gtggatatca aaaccgatcg cccgcgcttt tgggcatcgt ggttttaccc acagtctgct
    22921 ggcggtattt gcgctgctgg caacctttta ccttaaggtt cctgaaagct ggttcattcc
    22981 ggctgatgca ttgcagggca tggtgctggg ttatttgagc cacatacttg ccgatatgct
    23041 gacacccgcc ggtgttcccc tgctctggcc atgccgctgg cgtttccgct tgcctatcct
    23101 ggttccccaa aagggcaacc aactggaacg ttttatctgc atggcattat ttgtctggtc
    23161 ggtatggatg cctcattcat tacccgaaaa cagcgctgtt cgttggtcat cgcaaatgat
    23221 caatactttg cagatccagt ttcatcggct tattaagcat caggttgaat actaaaaagg
    23281 caaaaatcac ctttctggaa taagcaattc catttgaata taagagccag ctcacagttc
    23341 tgttaatctt gcgccaacac tatgactgct acgcagtgat agaaataata agatcaggag
    23401 aacggggatg aactttccat taattgcgaa catcgtggtg ttcgttgtac tgctgtttgc
    23461 gctggctcag acccgccata aacagtggag tctggcgaaa aaagtgctgg tgggtctggt
    23521 gatgggtgtg gtttttggcc tcgccctgca taccatttat ggttctgaca gccaggtact
    23581 taaagattct gtacagtggt ttaacattgt tggtaacggc tatgttcaac tgctgcaaat
    23641 gatcgttatg ccgttagtct ttgcctctat tctgagcgcg gttgcccgtc tgcataacgc
    23701 atcacagtta ggcaaaatca gttttctgac catcggaacg cttttgttta ccacgctgat
    23761 tgcggcgctg gtcggtgtgc tggtcaccaa cctgtttggt ttgacggctg aaggtctggt
    23821 tcagggtggt gcagaaactg cacgtttgaa cgccatcgaa agtaactatg ttggtaaagt
    23881 ctctgacctg agcgttccgc agctggtctt gtcctttatc ccgaaaaacc cgtttgccga
    23941 tttgaccgga gccaatccga cgtcaattat cagcgtggta atttttgccg cattcctcgg
    24001 cgtagctgcg ctgaagctgc tgaaggatga tgcgccgaaa ggtgaacgcg tcttaaccgc
    24061 tatcgatacc ctgcaaagct gggtgatgaa actggttcgc ctggtcatgc agctgacccc
    24121 ttacggcgtt ctggcgctga tgaccaaagt ggttgcaggt tctaacctgc aagacatcat
    24181 caaactggga agtttcgttg tcgcgtccta cctcggtctg ctgattatgt ttgcagtgca
    24241 tggcattctg ctgggcatta atggcgtgag cccgctgaag tacttccgta aggtatggcc
    24301 agttctgacg tttgccttta ccagccgttc cagtgctgcg tctatcccac tgaatgtgga
    24361 agcacaaacg cgtcgactcg gtgttcctga atccatcgcc agtttcgctg cctctttcgg
    24421 tgcaaccatt ggtcagaacg gctgtgccgg tttgtatccg gcgatgctgg cggtgatggt
    24481 tgcgcctacg gttggcatta acccgctgga cccgatgtgg attgcgacgc tggtcggtat
    24541 tgttaccgtt agttccgcag gcgttgccgg tgtcggtggt ggtgcaactt tcgccgcact
    24601 gattgtgctg cctgcgatgg gcctgcctgt aacgctggtg gcattgttaa tctccgttga
    24661 accgcttatc gacatggggc gtacggcgct aaacgttagt ggctcgatga ccgctggcac
    24721 gctgaccagc cagtggctga agcaaaccga taaagccatt ctggatagcg aagacgacgc
    24781 cgaactggca caccgttaat tcttatgctg gcaacggtcc gttttgtata ggagccgttg
    24841 ccttactttt taaatgttcc atcgcggcga tgcatactga ctcatattta aacagatcgt
    24901 cagcgaaaaa aatggctaac ttatcgatac attcctgact caatgaatgt gcttgtagcg
    24961 agaagcttaa aacctcatac ccaagacgtt ttctaagtga actatctgaa atactcataa
    25021 tctcttcaag cacaccactt cccattcccg gaagattcag gggattaaaa agaagattga
    25081 cattaagcat tgatattatc gaaggaaact ttaggagact ctcatttttt tgaatcgcag
    25141 caaaaatgct cccgacagga tgtatataat tttgttcata gtatatcgtt cttaaatagt
    25201 gaataatcaa cctgtttttt atattgatca aat
//
LOCUS       DADXDL010000068        25038 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.068, whole genome shotgun sequence.
ACCESSION   DADXDL010000068 DADXDL010000000
VERSION     DADXDL010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 25038)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25038)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25038
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.068"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(25..717)
                     /gene="ompL"
                     /locus_tag="IRB70_003270"
     CDS             complement(25..717)
                     /gene="ompL"
                     /locus_tag="IRB70_003270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porin OmpL"
                     /protein_id="HBC0633146.1"
                     /translation="MKKINAIILLSSLTSASVFAGAYVENREAYNLASDQGEVMLRVG
                     YNFDMGAGIMLTNTYTFQREDELKHGYNEIEGWYPLFKPTDKLTIQPGGLINDKSIGS
                     GGAVYLDVNYKFTPWFNLTVRNRFNHNNYSSTDLNGDLDNNDSYEIGNYWNFIITDKF
                     SYTFEPHYFYNINDFNSSNGTKHHWEITNTFRYRINEHWLPYIELRWLDRNVEPYHRE
                     QNQIRIGTKYFF"
     gene            complement(784..2187)
                     /locus_tag="IRB70_003271"
     CDS             complement(784..2187)
                     /locus_tag="IRB70_003271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633147.1"
                     /translation="MSDHNPLTLRLNLREKIAYGMGDVGSNLMLCIGTLYLLKFYTDE
                     LGMPAYYGGIIFLVAKFFTAFTDMLTGFLLDSRKNIGPKGKFRPFILYAAVPAALIAT
                     LQFIATTFSLPVKTTIATALFMMFGLSYSLMNCSYGAMIPAITKNPNERAQLAAYRQG
                     GATIGLLICTVAFIPLQSLFSDSTVGYACAALMFSIGGFIFMMLCYRGVKEHYVDTTP
                     TGHKASILKSFCAIFRNPPLLVLCIANLCTLAAFNIKLAIQVYYTQYVLNDINLLSWM
                     GFFSMGCILVGVLLVPLTVKCFGKKQVYLAGMVLWAVGDILNYFWGSNSFTFVMFSCV
                     AFFGTAFVNSLNWALVPDTVDYGEWKTGIRAEGSVYTGYTFFRKISAALAGFLPGIML
                     TQIGYVPNIAQSDATLQGLRQLIFIWPCALAIIAALTMGFFYTLNEKRFALIIEEINQ
                     RKNKEMATEEKTASVTL"
     gene            complement(2230..3618)
                     /locus_tag="IRB70_003272"
     CDS             complement(2230..3618)
                     /locus_tag="IRB70_003272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633148.1"
                     /translation="MSHITTEDPATLRLPFKEKLSYGIGDLASNILLDIGTLYLLKFY
                     TDVLGLPGTYGGIIFLISKFFTAFTDMGTGIMLDSRRKIGPKGKFRPFILYASFPVTL
                     LAIANFIGTPFDVTGKTVMATILFMLYGLFFSMMNCSYGAMVPAITKNPNERASLAAW
                     RQGGATLGLLLCTVGFVPVMNLIEGNQQLGYIFAATLFSLFGLLFMWICYSGVKERYV
                     ETQPTNPAQKKPGLLQSFRAIAGNRPLFILCIANLCTLGAFNVKLAIQVYYTQYVLND
                     PILLSYMGFFSMGCIFIGVFLMPGAVRRFGKKKVYIGGLLIWVLGDLLNYFFGGGSVS
                     FVAFSCLAFFGSAFVNSLNWALVSDTVEYGEWRTGVRSEGTVYTGFTFFRKVSQALAG
                     FFPGWMLTQIGYVPNVAQADHTIEGLRQLIFIYPSALAVVTIVAMGCFYSLNEKMYVR
                     IVEEIEARKRTA"
     gene            complement(3664..5700)
                     /gene="yihQ"
                     /locus_tag="IRB70_003273"
     CDS             complement(3664..5700)
                     /gene="yihQ"
                     /locus_tag="IRB70_003273"
                     /EC_number="3.2.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovosidase"
                     /protein_id="HBC0633149.1"
                     /translation="MDTPRPQLPDFQFHQNNDSFTLHFQQRLILTHSKDNPCLWIGSG
                     IADIDMFRGNFSIKDKLQEKIALTDAIVSQSPDGWLIHFSRGSDISATLRISADEQGR
                     LLLELQNDNLNHNRIWLRLAAQPEDHIYGCGEQFSYFDLRGKPFPLWTSEQGVGRNKQ
                     TYVTWQADCKENAGGDYYWTFFPQPTFVSTQKYYCHVDNSCYMNFDFSAPEYHELALW
                     EDKATLRFECADTYISLLEKLTALLGRQPELPDWIYDGVTLGIQGGTEVCQKKLDTMR
                     NAGVKVNGIWAQDWSGIRMTSFGKRVMWNWKWNSENYPQLDSRIKQWNKEGVQFLAYI
                     NPYVASDKDLCAEAASHGYLAKDASGGDYLVEFGEFYGGVVDLTNPEAYAWFKEVIKK
                     NMIELGCGGWMADFGEYLPTDTYLHNGVSAEIMHNAWPALWAKCNYEALEETGKLGEI
                     LFFMRAGSTGSQKYSTMMWAGDQNVDWSLDDGLASVVPAALSLAMTGHGLHHSDIGGY
                     TTLFEMKRSKELLLRWCDFSAFTPMMRTHEGNRPGDNWQFDGDAETIAHFARMTTVFT
                     TLKPYLKEAVALNAKSGLPVMRPLFLHYEDDAQTYTLKYQYLLGRDILVAPVHEEGRS
                     DWTLYLPEDNWVHAWTGEAFRGGEVTVNAPIGKPPVFYRADSEWAALFASLKSI"
     gene            complement(5808..6683)
                     /locus_tag="IRB70_003274"
     CDS             complement(5808..6683)
                     /locus_tag="IRB70_003274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBC0633150.1"
                     /translation="MDFFTLFSPDGAMVETSVVCIVIVLMFLYTFVGICAGFGGGLTT
                     MPLVTLMLPVKMATPLSVIVGTATALYATWLSRKETDWRSAMVLIIFSFLGIPVGLYA
                     LSYLPDHFMKVGLGGFLILYSFYSMFIPRLPIYDRNWIAAPIGAVAGALGAAFSTNGP
                     PMVIYGMLRNLGPAAFRGTLNAFFTANNIAVIGGLATSGILTVSIFKLVLFCIPTMIL
                     GSLVGQYVHKRISVKVFRVMVFLLLIASGSMLIKGALGIPAAAALLPPFTLLVILQLA
                     FGKKVAAIRRAEESK"
     gene            complement(6744..7646)
                     /locus_tag="IRB70_003275"
     CDS             complement(6744..7646)
                     /locus_tag="IRB70_003275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001417111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose-1-epimerase"
                     /protein_id="HBC0633151.1"
                     /translation="MQITNMHCSGQTVSLAAGDYHATIVTVGAGLAELTFQGCHLVIP
                     HKPEEMPLAHLGKVLIPWPNRIANGCYRYQGQEYQLPINEHGSKAAIHGLLAWRDWQI
                     SELTATSVTLTAFLPPSYGYPFMLASQVVYSLNARTGLSVEIASQNIGTVTAPYGVGI
                     HPYLTCNLTSVDDYLFQLPAEQVYAVDEHANPTTLHHVDELNLNFTRATKIAATKIDH
                     TFKTANDLWEITITHPQQALSVSLCSDQPWVQVYSGEKLQRQGLAVEPMSCPPNAFNS
                     GIDLLLLEPGKTHRLFFNIHGQHN"
     gene            complement(7714..8955)
                     /gene="yihS"
                     /locus_tag="IRB70_003276"
     CDS             complement(7714..8955)
                     /gene="yihS"
                     /locus_tag="IRB70_003276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfoquinovose isomerase"
                     /protein_id="HBC0633152.1"
                     /translation="MKWFNTLSHNRWLEQETDRIFDFGKNAVVPTGFGWLGNKGQIKE
                     EMGTHLWITARMLHVYSVAAAMGRPGAYSLVDHGIKAMNGALRDKKYGGWYACVNDEG
                     VVDASKQGYQHFFALLGAASAVTTGHPEARKLLDYTIEIIEKYFWSEEEQMCLESWDE
                     AFSKTEEYRGGNANMHAVEAFLIVYDVTHDKKWLDRAIRVASVIIHDVARNNHYRVNE
                     HFDTQWNPLPDYNKDNPAHRFRAFGGTPGHWIEWGRLMLHIHAALEARGEQPPAWLLE
                     DAKGLFNATVRDAWAPDGADGIVYTVDWEGKPVVRERVRWPIVEAMGTAYALYTVTGD
                     RQYETWYQTWWEYCIKYLMDYENGSWWQELDADNKVTTKVWDGKQDIYHLLHCLVIPR
                     IPLAPGLAPAVAAGLLDVNAK"
     gene            complement(8971..9849)
                     /gene="yihT"
                     /locus_tag="IRB70_003277"
     CDS             complement(8971..9849)
                     /gene="yihT"
                     /locus_tag="IRB70_003277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructosephosphate aldolase"
                     /protein_id="HBC0633153.1"
                     /translation="MNKYTINDITRASGGFAMLAVDQREAMRMMFAAAGAPAPVADSV
                     LTDFKVNAAKTLSPYASAILVDQQFCYRQVVEQNAIAKSCAMIVAADEFIPGNGIPVD
                     SVVIDRKINPLQIKQDGGKALKLLVLWRSDEDAQQRLDMVKEFNELCHSHGLVSIIEP
                     VVRPPRRGDKFDREQAIIDAAKELGDSGADLYKVEMPLYGKGPQQELLSASQRLNDHI
                     NMPWVILSSGVDEKLFPRAVRVAMTAGASGFLAGRAVWASVVGLPDNELMLRDVCAPK
                     LQQLGDIVDEMIAKRR"
     gene            complement(9873..10769)
                     /gene="yihU"
                     /locus_tag="IRB70_003278"
     CDS             complement(9873..10769)
                     /gene="yihU"
                     /locus_tag="IRB70_003278"
                     /EC_number="1.1.1.373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfolactaldehyde 3-reductase"
                     /protein_id="HBC0633154.1"
                     /translation="MAAIAFIGLGQMGSPMASNLLQQGHQLRVFDVNAEAVRHLVDKG
                     ATPAANPAQAAKGAEFIITMLPNGDLVRHVLFGENGVCESLSSDALVIDMSTIHPLQT
                     DKLIADMQARGFSMMDVPVGRTSANAITGTLLLLAGGTAEQVERATPILMAMGSELIN
                     AGGPGMGIRVKLINNYMSIALNALSAEAAVLCEALNLPFDVAVKVMSGTAAGKGHFTT
                     SWPNKVLSGDLSPAFMIDLAHKDLGIALDVANQLHVPMPLGAASREVYSQARAAGRGR
                     QDWSAILEQVRVSAGMTAKVKM"
     gene            10937..11833
                     /gene="yihV"
                     /locus_tag="IRB70_003279"
     CDS             10937..11833
                     /gene="yihV"
                     /locus_tag="IRB70_003279"
                     /EC_number="2.7.1.184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418319.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfofructose kinase"
                     /protein_id="HBC0633155.1"
                     /translation="MIRVACVGITVMDRIYYVEGLPTESGKYVAKNYTEVGGGPAATA
                     AVAAARLGAQVDFIGRVGDDDTGNSLLAELESWGVNTRYTKRYNEAKSSQSAIMVDTK
                     GERIIINYPSPDLLPDAEWLEEIDFSQWDVVLADVRWHEGAKKAFTLARQAGVMTVLD
                     GDITPQDISELVALSDHAAFSEPGLARLTGVKEMASALKQAQTLTNGHVYVTQGSAGC
                     DWLENGGRQHQPAFKVDVVDTTGAGDVFHGALAVALATGGDLAESVRFASGVAALKCT
                     RPGGRAGIPDCDQTRSFLSLFV"
     gene            11867..12652
                     /locus_tag="IRB70_003280"
     CDS             11867..12652
                     /locus_tag="IRB70_003280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418320.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBC0633156.1"
                     /translation="MSLTELTGNPRHDQLLMLIAERGYMNIDELANLLDVSTQTVRRD
                     IRKLSEQGLITRHHGGAGRASSVVNTAFEQREVSQTEEKKAIAEAVADYIPDGSTIFI
                     TIGTTVEHVARALLNHNHLRIITNSLRVAHILYHNPRFEVMVPGGTLRSHNSGIIGPS
                     AASFVADFRADYLVTSVGAIESDGALMEFDVNEANVVKTMMAHARNILLVADHTKYHA
                     SAAVEIGNVAQVTALFTDELPPAALKSRLQDSQIEIILPQEDT"
     gene            12751..13350
                     /gene="yihX"
                     /locus_tag="IRB70_003281"
     CDS             12751..13350
                     /gene="yihX"
                     /locus_tag="IRB70_003281"
                     /EC_number="3.1.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphatase"
                     /protein_id="HBC0633157.1"
                     /translation="MLYIFDLGNVIVDIDFNRVLGAWSDLTRVPLATLKKSFHMGEAF
                     HQHERGEISDEAFAEALCHEMALPLSYEQFSHGWQAVFVALRPEVIAIMHKLREQGHR
                     VVVLSNTNRLHTTFWPEEYPEIRDAADHIYLSQDLGMRKPEARIYQHVLQAEGFSPDD
                     TVFFDDNADNIEGANQLGITSILVKDKTTIPDYFAKVLC"
     gene            13344..14216
                     /locus_tag="IRB70_003282"
     CDS             13344..14216
                     /locus_tag="IRB70_003282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="virulence factor BrkB family protein"
                     /protein_id="HBC0633158.1"
                     /translation="MLKTIQDKARHRTRPLWAWLKLLWQRIDEDNMTTLAGNLAYVSL
                     LSLVPLVAVVFALFAAFPMFSDVSIQLRHFIFANFLPATGDVIQRYIEQFVANSNKMT
                     AVGACGLIVTALLLMYSIDSALNTIWRSKRARPKIYSFAVYWMILTLGPLLAGASLAI
                     SSYLLSLRWASDLNTVIDNVLRIFPLLLSWISFWLLYSIVPTIRVPNRDAIVGAFVAA
                     LLFEAGKKGFALYITMFPSYQLIYGVLAVIPILFVWVYWTWCIVLLGAEITVTLGEYR
                     KLKQAAEQEEDDEP"
     gene            14213..14650
                     /gene="dtd"
                     /locus_tag="IRB70_003283"
     CDS             14213..14650
                     /gene="dtd"
                     /locus_tag="IRB70_003283"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000560980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBC0633159.1"
                     /translation="MIALIQRVTRASVTVEGEVTGEIGAGLLVLLGVEKDDDEQKANR
                     LCERVLGYRIFSDAEGKMNLNVQQAGGSVLVVSQFTLAADTERGMRPSFSKGASPDRA
                     EALYDYFVERCRQQEMNTQTGRFAADMQVSLVNDGPVTFWLQV"
     gene            14695..15636
                     /gene="fabY"
                     /locus_tag="IRB70_003284"
                     /gene_synonym="yiiD"
     CDS             14695..15636
                     /gene="fabY"
                     /locus_tag="IRB70_003284"
                     /gene_synonym="yiiD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001666856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid biosynthesis protein FabY"
                     /protein_id="HBC0633160.1"
                     /translation="MYHLRVPQTEEELERYYQFRWEMLRKPLHQPKGSERDAWDAMAH
                     HQMVVDEQGNLVAVGRLYINADNEASIRFMAVHPDVQDKGLGTLMAMTLESVARQEGV
                     KRVTCSAREDAVEFFAKLGFVNQGEITTPTTTPIRHFLMIKPVATLDDILHRGDWCAQ
                     LQQAWYEHIPLSEKMGVRIQQYTGQKFITTMPETGNQNPHHTLFAGSLFSLATLTGWG
                     LIWLMLRERHLGGTIILADAHIRYSKPISGKPHAVADLGALSGDLDRLARGRKARVQM
                     QVEIFGDETPGAVFEGTYIVLPAKPFGPYEEGGNEEE"
     gene            complement(15700..16608)
                     /locus_tag="IRB70_003285"
     CDS             complement(15700..16608)
                     /locus_tag="IRB70_003285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBC0633161.1"
                     /translation="MALEKGIAELVEEFIAAGRPSSRQQSIAQRREGYIASAVLAGET
                     ETRVDIQTIELEAMTLRIVSPLNAPTLLPTIIYYYGGCFVSGGFATHDNQLRQLAYYG
                     QCRVIAVQYRLAPEHTFPAAHDDAQRGAELVWQHAERLGVDKQRITLAGDSAGGHLAL
                     VTALRLKRAGEWQPAQLILIYPMLDATAHFESYIRNGHDYIITRDTLLSGFEMYLPGI
                     ERRHPEASPLWRDDFNGLPPVHIITAEYDPLCDEGEALYHRMTGQGVQCTCQRYLGVI
                     HGFFQLGGISEAARSALRDVAWRAGR"
     gene            16837..17148
                     /locus_tag="IRB70_003286"
     CDS             16837..17148
                     /locus_tag="IRB70_003286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000897300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBC0633162.1"
                     /translation="MLFIETEIFTEDVQKLLTDDEFSRFQFFLALNPDYGEVIPETGG
                     LRKVRWVSGGKGKRAGVRVIYFHQVKHYEIRLLLIYRKGIKDDLSPQEKAMLRLLNTR
                     W"
     gene            17149..17439
                     /locus_tag="IRB70_003287"
     CDS             17149..17439
                     /locus_tag="IRB70_003287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000356400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0633163.1"
                     /translation="MDKALFERLTHSMAQMNEIIEGTRQPSRTFEVDAMKIKEIRRAS
                     GLSQSKFADLISVSVDTLRNWEQGRRSPTGPAKALLRAIANDPQHVLQALNR"
     gene            18044..18262
                     /locus_tag="IRB70_003288"
     CDS             18044..18262
                     /locus_tag="IRB70_003288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312842.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HBC0633164.1"
                     /translation="MAMNTVFLHLSEEAIKRLNKLRGWRKVSRSAILREAVEQYLERQ
                     QFPVRKAKGGRQRGETVVVDDQCKEHKE"
     gene            complement(18477..19406)
                     /gene="fdhE"
                     /locus_tag="IRB70_003289"
     CDS             complement(18477..19406)
                     /gene="fdhE"
                     /locus_tag="IRB70_003289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory protein FdhE"
                     /protein_id="HBC0633165.1"
                     /translation="MSIRIIPQDELGSSEKRTADMIPPLLFPRLKNLYNRRAERLREL
                     AENNPLGDYLRFAALIAHAQEVVLYDHPLEMDLTTRIKEASAQGKPPLDIHVLPRDKH
                     WQKLLMALIAELKPEMSGPALAVIENLEKASTQELEDMASALFASDFSSVSSDKAPFI
                     WAALSLYWAQMANLIPGKARAEYGEQRQYCPVCGSMPVSSMVQIGTTQGLRYLHCNLC
                     ETEWHVVRVKCSNCEQSGKLHYWSLDDEQAAIKAESCDDCGTYLKILYQEKEPKVEAV
                     ADDLASLVLDARMEQEGYARSSINPFLFPGEGE"
     gene            complement(19403..20038)
                     /gene="fdoI"
                     /locus_tag="IRB70_003290"
     CDS             complement(19403..20038)
                     /gene="fdoI"
                     /locus_tag="IRB70_003290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312845.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase cytochrome b556 subunit"
                     /protein_id="HBC0633166.1"
                     /translation="MKRRDTIVRYTAPERINHWITAFCFILAAVSGLGFLFPSFNWLM
                     QIMGTPQLARILHPFVGVVMFASFIIMFFRYWHHNLINRDDIFWAKNIRKIVVNEEVG
                     DTGRYNFGQKCVFWAAIIFLVLLLVSGVIIWRPYFAPAFSIPVIRFALMLHSFAAVAL
                     IVVIMVHIYAALWVKGTITAMVEGWVTSAWAKKHHPRWYREVRKTTEKKAE"
     gene            complement(20035..20937)
                     /gene="fdoH"
                     /locus_tag="IRB70_003291"
     CDS             complement(20035..20937)
                     /gene="fdoH"
                     /locus_tag="IRB70_003291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase O subunit beta"
                     /protein_id="HBC0633167.1"
                     /translation="MAYQSQDIIRRSATNGLTPAPQARDFQEEVAKLIDVTTCIGCKA
                     CQVACSEWNDIRDTVGNNIGVYDNPNDLSAKSWTVMRFSEVEQNDKLEWLIRKDGCMH
                     CSDPGCLKACPAEGAIIQYANGIVDFQSEQCIGCGYCIAGCPFDIPRLNPEDNRVYKC
                     TLCVDRVVVGQEPACVKTCPTGAIHFGTKESMKTLASERVAELKTRGYDNAGLYDPAG
                     VGGTHVMYVLHHADKPNLYHGLPENPEISETVKFWKGIWKPLAAVGFAATFAASIFHY
                     VGVGPNRADEEENNLHEEKDEERK"
     gene            complement(20950..24000)
                     /gene="fdnG"
                     /locus_tag="IRB70_003292"
     CDS             complement(20950..24000)
                     /gene="fdnG"
                     /locus_tag="IRB70_003292"
                     /EC_number="1.17.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(23413..23415),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase-N subunit alpha"
                     /protein_id="HBC0633168.1"
                     /translation="MQVSRRQFFKICAGGMAGTTAAALGFAPSVALAETRQYKLLRTR
                     ETRNTCTYCSVGCGLLMYSLGDGAKNAKASIFHIEGDPDHPVNRGALCPKGAGLVDFI
                     HSESRLKFPEYRAPGSDKWQQISWEEAFDRIAKLMKEDRDANYIAQNAEGVTVNRWLS
                     TGMLCASASSNETGYLTQKFSRALGMLAVDNQARVUHGPTVASLAPTFGRGAMTNHWV
                     DIKNANLVVVMGGNAAEAHPVGFRWAMEAKIHNGAKLIVIDPRFTRTAAVADYYAPIR
                     SGTDIAFLSGVLLYLLNNEKFNREYTEAYTNASLIVREDYGFEDGLFTGYDAEKRKYD
                     KSSWTYELDENGFAKRDTTLQHPRCVWNLLKQHVSRYTPDVVENICGTPKDAFLKVCE
                     YIAETSAHDKTASFLYALGWTQHSIGAQNIRTMAMIQLLLGNMGMAGGGVNALRGHSN
                     IQGLTDLGLLSQSLPGYMTLPSEKQTDLQTYLTANTPKPLLEGQVNYWGNYPKFFVSM
                     MKAFFGDKATAENNWGFDWLPKWDKGYDVLQYFEMMKEGKVNGYICQGFNPVASFPNK
                     NKVIGCLSKLKFLVTIDPLNTETSNFWQNHGELNEVDSSKIQTEVFRLPSTCFAEENG
                     SIVNSGRWLQWHWKGADAPGIALTDGEILSGIFLRLRKMYAEQGGANPDQVLNMTWNY
                     AIPHEPKSEEVAMESNGKALADITDPATGAVIVKKGQQLSSFAQLRDDGTTSCGCWIF
                     AGSWTPEGNQMARRDNADPSGLGNTLGWAWAWPLNRRILYNRASADPQGNPWDPKRQL
                     LKWDGTKWTGWDIPDYSAAPPGSGVGPFIMQQEGMGRLFALDKMAEGPFPEHYEPFET
                     PLGTNPLHPNVISNPAARIFKDDAEALGKADKFPYVGTTYRLTEHFHYWTKHALLNAI
                     LQPEQFVEIGESLANKLGIAQGDTVKVSSNRGYIKAKAVVTKRIRTLKANGKDIDTIG
                     IPIHWGYEGVAKKGFIANTLTPFVGDANTQTPEFKSFLVNVEKV"
     gene            24194..25027
                     /gene="fdhD"
                     /locus_tag="IRB70_003293"
     CDS             24194..25027
                     /gene="fdhD"
                     /locus_tag="IRB70_003293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate dehydrogenase accessory
                     sulfurtransferase FdhD"
                     /protein_id="HBC0633169.1"
                     /translation="MKKTQQKEIENVTSVTGVRQIELWRRDDLQHPRLDEVAEEVPVA
                     LVYNGISHVVMMASPKDLEYFALGFSLSEGIIESPRDIFGMDVVPSCNGLEVQIELSS
                     RRFMGLKERRRALAGRTGCGVCGVEQLNDIGKPVQPLPFTQTFDLNKLDDALRHLNDF
                     QPVGQLTGCTHAAAWMLPSGELVGGHEDVGRHVALDKLLGRRSQEGESWQQGAVLVSS
                     RASYEMVQKSAMCGVEILFAVSAATTLAVEVAERCNLTLVGFCKPGRATVYTHPQRLS
                     N"
BASE COUNT         6122 a         6355 c         6509 g         6052 t
ORIGIN      
        1 tcagcggctt tttacatttt cacatcagaa gaaatacttc gtcccgatac gaatctggtt
       61 ttgctcgcgg tggtacggtt cgacattacg atctaaccag cgcaattcaa tatagggcaa
      121 ccagtgctca ttaatgcgat aacggaaggt gttagtgatt tcccagtgat gcttcgtacc
      181 attgctgcta ttgaaatcat taatgttata aaaataatgc ggttcaaagg tatatgagaa
      241 cttatcggta ataataaagt tccagtagtt gccaatctcg tagctgtcat tattatccag
      301 atcaccgttc aaatcggttg agctgtagtt attatggtta aaacgattac gtaccgtcag
      361 gttaaaccat ggagtaaatt tgtagttaac atccagataa acagcaccac ccgaaccgat
      421 actcttatca ttaattaagc caccgggctg gatggttaat ttatcggttg gtttgaataa
      481 cggataccaa ccttcgattt cgttatatcc atgtttgagt tcatcttctc gctgaaaggt
      541 gtaggtattg gttaacataa tacccgcgcc catatcgaag ttataaccca cacgtagcat
      601 aacctcgccc tgatcggagg cgagattata tgcctccctg ttttcgacgt atgcgccagc
      661 aaataccgag gcagaggtca gagaggataa tagaattatt gcattaatct ttttcataat
      721 aagtccattt ttaaacgtag ggaggccgcc acccaccagg atggaaatag cggctattga
      781 catttataac gttacggaag ccgttttttc ttctgtcgcc atctctttat ttttgcgttg
      841 gttgatttcc tcaataatca atgcaaaccg tttttcattg agtgtgtaaa agaatcccat
      901 cgtcaatgca gcaataattg ccagtgcaca aggccagata aaaatgagct gacgcaaacc
      961 ctgtaatgtc gcatcacttt gcgcgatgtt gggaacataa ccgatttgcg tcagcataat
     1021 gcctggcaag aagccagcaa gtgcggcaga aattttacga aagaaggtat aaccggtata
     1081 aacagaacct tcggcacgaa taccggtttt ccattcaccg taatctacgg tatctggcac
     1141 cagtgcccag ttcaggctgt ttacaaaggc cgtgccaaaa aaggcgacac aagagaacat
     1201 gacgaaagtg aaagagttac ttccccagaa ataattcagg atatcaccaa ccgcccatag
     1261 caccatgcca gctaaataaa cctgtttttt accaaaacat tttacagtta atggcaccag
     1321 taatacgccg acgaggatac atcccatact gaaaaatccc atccacgaca ataaattaat
     1381 atcattcagc acatactggg tgtaatagac ctgaatcgcc agtttgatat taaatgccgc
     1441 cagggtacac aggttagcaa tgcacaaaac cagcaatggc ggattacgaa atatcgcgca
     1501 aaaagatttg agaatactgg ctttatgtcc ggttggcgtc gtgtctacat aatgctcttt
     1561 gacgcctctg tagcacagca tcataaaaat aaagccacca atggagaaca tcagtgccgc
     1621 gcaggcataa ccgacggtgg agtcagaaaa aagcgactgc aatggaataa atgctacggt
     1681 acaaatcaat agccctatgg ttgcgccgcc ctggcggtaa gccgcaagct gcgcgcgctc
     1741 attcgggttt ttggtaattg ccgggatcat cgcgccatac gagcagttca tcagactgta
     1801 tgaaagtcca aacatcataa acagcgcggt ggcaatcgtc gttttaaccg gcaaactaaa
     1861 agtggtggcg ataaactgga gcgttgcaat taacgccgcc ggaaccgctg catataaaat
     1921 aaagggacga aatttgcctt taggcccaat atttttccgc gagtcgagta aaaatccggt
     1981 gagcatatcg gtaaatgcgg taaaaaactt cgccaccaga aagataatcc cgccatagta
     2041 agcaggcatc cctaattcat cggtataaaa tttgaggaga tacagagtac cgatgcagag
     2101 cattaaattc gaaccgacgt cgcccatacc ataggcgatt ttttcccgca gattcagtct
     2161 taatgtcagt ggattatggt cagacataat cactccttat aacgccccgc agggcgttgt
     2221 ttattataat tacgccgtgc gtttacgggc ttctatctct tcaacaatgc ggacgtacat
     2281 cttctcgttc agactgtaga agcaacccat tgccacgatg gtgactactg ccagtgcgct
     2341 tgggtagatg aagatcagtt ggcgcaaccc ttcgatagtg tggtcagcct gggcgacgtt
     2401 tggcacatag ccgatttgcg tcagcatcca gcctgggaag aaacctgcca gcgcctgaga
     2461 tactttgcga aagaaggtga aaccggtgta gaccgtacct tccgaacgca caccggtgcg
     2521 ccactcgccg tactcgacgg tgtcggaaac cagcgcccag ttcaggctgt taacaaacgc
     2581 tgagccgaag aatgccaggc aggagaacgc cacgaagctg accgaaccgc cgccaaagaa
     2641 atagttgagc agatcgccaa gcacccaaat cagcaggccg ccgatataga ccttcttctt
     2701 accaaaacgt ctgactgcgc cgggcatcag gaacacgccg atgaaaatac agcccatgct
     2761 gaaaaatccc atatatgaca acaggatggg atcgttgagc acgtactggg tgtaatagac
     2821 ctgaatggcg agcttgacgt taaacgcccc taaagtgcag aggttggcaa tacacagaat
     2881 gaacagtggg cggttaccag caatcgcgcg gaaagactgc aacaagccag gctttttttg
     2941 cgccggattg gtaggttggg tttcgacata acgctctttc acgcccgagt agcagatcca
     3001 cataaacagc aggccgaaca gtgaaaacag cgtggcggcg aagatatagc caagttgctg
     3061 attaccttcg ataagattca taaccggcac gaatcccacc gtacacagca gcaggcctaa
     3121 tgtagcgcca ccctgacgcc atgctgccag cgatgcacgt tcgttggggt ttttagtaat
     3181 agcggggacc atcgcgccat acgagcagtt catcatgctg aaaaacagtc cgtaaagcat
     3241 aaacaggatg gtggccatca ccgttttacc ggtgacatcg aacggcgtac cgataaagtt
     3301 ggcgatcgcc agcagggtga ccgggaatga cgcatacaga ataaaaggac ggaacttgcc
     3361 ttttgggccg atcttgcgtc gggaatccag catgatgcct gttcccatat cggtaaacgc
     3421 agtaaagaat tttgaaatca aaaagataat gccgccatag gtgccaggca gccccagaac
     3481 gtcggtataa aacttcaaaa gataaagcgt accaatatcc agcaggatgt tagaggccag
     3541 gtcgccaata ccgtaagaga gtttctcttt aaagggcagg cgtaaagttg ctggatcttc
     3601 cgttgtgatg tgactcatcg ttgttctccc tttgcccgtg agtttcccca cgggcggatg
     3661 tgattagatg ctttttaacg acgcgaacag tgccgcccat tcgctatcgg cgcgataaaa
     3721 gaccggcggt ttaccgatgg gcgcattaac ggtaacttcc ccgccccgga acgcttcacc
     3781 cgtccaggca tggacccagt tatcctccgg cagatagagc gtccagtcgc tacggccttc
     3841 ttcatgcacc ggagcgacca gaatgtcgcg gcctaacagg tactgatatt tcagggtgta
     3901 ggtctgcgcg tcgtcttcgt aatgcaggaa cagcgggcgc ataaccggca ggccggactt
     3961 cgcattcagc gcgacggcct ctttcaggta aggtttcagg gtggtgaaga cggtggtcat
     4021 acgggcaaaa tgggcgatgg tttccgcgtc gccgtcaaac tgccagttgt cgccaggacg
     4081 gttaccttcg tgggtgcgca tcatcggcgt gaaggcgctg aaatcgcacc agcgcagcag
     4141 cagctctttg ctgcgcttca tctcaaacag ggtggtgtaa ccgccaatat cgctgtgatg
     4201 caggccatgt ccggtcattg ccagcgacag cgccgccggg acaaccgacg ccaggccatc
     4261 gtcgagactc cagtcgacgt tctggtcgcc cgcccacatc atggtggagt atttctggct
     4321 accggtagaa ccggcgcgca taaagaaaag gatctcgcca agcttgcccg tttcttcaag
     4381 ggcttcgtag ttacatttcg cccacagtgc gggccaggcg ttatgcataa tttccgcgct
     4441 gacgccgtta tgcaggtaag tgtcggtggg cagatactcg ccgaagtcag ccatccagcc
     4501 gccgcagccg agttcaatca tgttcttttt gatcacttcc ttgaaccagg cgtaggcttc
     4561 tggattggtg agatcgacaa cgccgccata gaactcgcca aactccacca gatagtcgcc
     4621 gccagaggca tcttttgcca gatagccgtg tgaagccgcc tcggcgcaga ggtccttatc
     4681 gctggcaaca tacgggttga tgtaggcgag gaactgcacg ccttctttgt tccactgttt
     4741 aatacgcgaa tccagttgcg gatagttttc gctgttccac ttccagttcc acatcacacg
     4801 tttaccaaac gaggtcatac ggatcccgga ccagtcctgc gcccagatgc cgttgacctt
     4861 cacgcccgcg ttacgcatgg tgtccagttt cttctggcac acctcagtgc cgccctgaat
     4921 gccgagcgtt accccgtcat aaatccagtc gggcagttct ggctggcgtc ccagcagggc
     4981 agttaatttt tccagcaggg agatgtatgt atcagcacat tcaaaacgca gcgttgcttt
     5041 gtcttcccac agcgccagtt catggtattc cggggcgcta aagtcgaagt tcatgtagca
     5101 actgttatca acatggcagt aatacttctg cgtgctgaca aacgtaggct gtgggaagaa
     5161 agtccagtaa tagtcgccgc ccgcgttctc tttgcagtcg gcctgccagg tgacataggt
     5221 ttgcttgttg cgaccaacgc cttgttcact ggtccatagc gggaacggtt tgccgcgcag
     5281 atcaaagtag gagaattgtt caccgcagcc gtagatatgg tcctctggtt gagcggcaag
     5341 gcgcagccag atacggttgt ggttaaggtt gtcgttttgt agttccagca ataaacggcc
     5401 ctgttcgtcg gcagagatac gcagcgtggc gctaatgtca gaaccacggc tgaaatggat
     5461 taaccaacca tccggtgact ggctgacgat ggcgtcggta agcgcaattt tctcctgtag
     5521 tttatcttta atgctgaaat tgccgcggaa catatcgata tccgcaatac ctgaaccaat
     5581 ccataaacaa ggattatctt tgctatgggt taaaataaga cgctgttgaa aatgtagggt
     5641 aaaactgtcg ttattctgat gaaactgaaa atctggtaat tgtgggcgtg gcgtatccat
     5701 aaataatctc catagagtat aaagctaata tttcatgcca tcctgttgtt acaggtttca
     5761 ttaattaaag aatgtgtgcg ggtataaatt aaaacccgca taagtgatta tttactttct
     5821 tcagcccggc ggattgccgc cactttttta ccaaatgcca gttgcagtat aactaacaag
     5881 gtaaacggag gcagaagtgc ggcagcggcg ggaattccca gtgcgccttt tatcaacata
     5941 gaaccggagg caatcagcaa caaaaagacc atcacacgga acactttgac tgaaatgcgt
     6001 ttatgcacat attgtccaac cagtgaaccg aggatcatgg tgggaataca aaacagcacc
     6061 agtttaaaga tagaaacagt caaaattccg ctggtcgcca gcccgccgat caccgcgatg
     6121 ttgtttgcgg tgaagaaagc gttcagagtg ccacgaaatg ccgccgggcc taagttacgc
     6181 agcataccgt agataaccat cggcggtccg ttggttgaga acgccgcgcc taatgcgcca
     6241 gctactgcgc cgataggtgc ggcgatccag ttacggtcat aaatcggcag gcgaggaata
     6301 aacatgctgt aaaacgagta aaggataagg aatccgccta agcccacttt cataaaatgg
     6361 tcgggtaaat acgacagcgc atataaaccg acgggtattc ccagaaacga gaaaataatc
     6421 agtaccattg ccgatcgcca atccgtttct ttacgtgaca gccaggtggc gtacaaggcg
     6481 gtcgcggtgc cgacaatcac cgagagcgga gttgccattt ttacggggag cattaacgtg
     6541 acgagcggca tagtggttaa accaccgcca aatcccgcgc atatccccac aaaggtataa
     6601 agaaacatta acacgataac gatacatacc acgcttgttt ccaccatggc cccatccggc
     6661 gaaaataacg taaaaaagtc cataatattt cctgttgtgt aaatacaacc ctaaacaatg
     6721 atctcgttct tttcttaata aaattaattg tgctgcccgt gaatattaaa aaacaggcgg
     6781 tgcgtttttc ctggttccag taataataag tcgatacctg aattaaaggc gttaggcggg
     6841 caactcatag gttcaactgc cagtccctga cgctgtaatt tttctccgct ataaacctgc
     6901 acccagggtt gatcggaaca gaggctcacc gaaagcgcct gttgtggatg ggtaatggtt
     6961 atttcccaca gatcattagc ggttttaaag gtatggtcta tttttgtcgc ggctattttt
     7021 gtcgcccgcg tgaaatttaa attcagctca tcaacgtggt gaagcgttgt cggatttgcg
     7081 tgctcatcga cggcataaac ctgttctgcc ggaagctgga aaagatagtc atcaacagat
     7141 gttaagttgc aggttaaata aggatgaata cccacaccat aaggtgcggt cacagtacca
     7201 atattctggc ttgcgatctc aacggaaagg cccgtgcgag cgttgagcga ataaacaacc
     7261 tgcgaagcca gcataaacgg atagccgtaa ctgggcggca gaaaagctgt cagggtaacg
     7321 ctggtggcgg ttaattcgct aatttgccag tcacgccagg caagcagccc gtgaatagcg
     7381 gcttttgaac catgttcatt aatgggtaac tgatattcct gcccctgata gcgataacag
     7441 ccgttggcga tccggttcgg ccacggaata agcactttac ccagatgcgc cagcggcatc
     7501 tcttcgggtt tgtgcgggat gactaaatga caaccctgaa aggttaattc agccagacca
     7561 gcaccaaccg tcacgatagt cgcgtgataa tcccccgcgg caagtgaaac ggtttgtcca
     7621 ctgcaatgca tgttggtgat ttgcatacga ggcaccttta ttgaataacg acatacccgg
     7681 catgtagcct gatatgccgt tatttcagct cagttatttc gcattcacgt ccagcagacc
     7741 cgccgcaact gccggagcca ggcctggcgc taacgggata cgcgggatca ccaggcaatg
     7801 cagcaggtga taaatatcct gtttgccgtc ccagactttg gtggtgacct tattgtccgc
     7861 atccagctcc tgccaccagg aaccattttc atagtccatc aggtacttaa tgcagtactc
     7921 ccaccatgtc tgataccagg tttcgtactg gcgatcgccg gtgacggtgt agagcgcgta
     7981 agccgtaccc atcgcctcga cgataggcca acgcacacgt tcgcgaacga ccggttttcc
     8041 ttcccagtca acggtataaa caatcccgtc cgcaccatcg ggcgcccagg catcgcgcac
     8101 ggtggcgttg aacagacctt tggcatcttc taacagccag gctggcggct gttcgccgcg
     8161 ggcttccagg gcggcatgga tgtgcagcat taaacgaccc cactcgatcc agtggcctgg
     8221 cgtgcctccg aatgcgcgga agcggtgcgc cgggttatct ttgttgtaat ccggcagcgg
     8281 attccactgg gtatcgaagt gctcgttaac gcgataatga ttatttctgg cgacgtcgtg
     8341 gataatgacg gaagccacgc gaatcgcgcg atccagccat tttttgtcat gggtgacgtc
     8401 atagacaatc aggaaggctt ccaccgcgtg catattggca ttgccgccgc gatactcttc
     8461 ggttttgctg aaggcttcat cccaggactc caggcacatc tgctcttctt cgctccagaa
     8521 gtatttctcg ataatttcaa tggtgtaatc gagcagcttg cgcgcttccg ggtgacccgt
     8581 tgtgacggca ctggcggcac ccagcagggc aaagaaatgt tgatagccct gtttggaggc
     8641 atccaccacg ccctcgtcat tcacacaggc ataccagccg ccatattttt tatcgcgcag
     8701 tgcgccattc atggctttga taccgtgatc aaccaacgag taagcgccag ggcggcccat
     8761 cgccgcagca acggaataaa cgtgcagcat acgggcggtg atccacagat gcgtgcccat
     8821 ctcttctttg atttgccctt tattgcccag ccagccaaag ccagtcggca ccacggcatt
     8881 cttaccaaaa tcaaagatgc gatcggtttc ctgttccagc cagcggttgt gacttaaggt
     8941 gttaaaccat ttcatttttg tatccccatc ttaacggcgt ttagctatca tttcgtcgac
     9001 gatatcgcca agttgttgta atttcggtgc gcaaacgtca cgcagcatca gctcgttgtc
     9061 tggtaaaccg acaaccgatg cccagacggc acgaccagcc aggaagcccg atgcacccgc
     9121 tgtcattgcc acgcgtacgg cacgcgggaa cagtttttcg tcgacaccgg aagaaagtat
     9181 cacccacggc atattgatat ggtcattcag acgttgtgaa gcactgagaa gctcttgttg
     9241 cggaccttta ccgtaaagcg gcatttcaac tttgtagagg tcagcgccac tgtcgcccag
     9301 ctctttggca gcatcgatga tcgcttgttc gcgatcgaat ttatcgccac gacgtggtgg
     9361 gcggacgact ggctcaataa tgcttaccag gccgtgtgag tggcacagtt cgttaaactc
     9421 tttcaccata tccagacgtt gctgcgcatc ttcatcacta cgccacagca ccagcagttt
     9481 taaggctttg ccaccgtctt gtttgatttg tagcggattg attttgcggt caatgaccac
     9541 gctatctacc ggaataccgt tgccaggaat gaactcatcg gcggcgacaa tcatggcgca
     9601 acttttggca atcgcgtttt gctcaaccac ctggcggtaa cagaattgtt gatctaccag
     9661 aatcgccgag gcataaggcg agagggtctt cgccgcgtta actttgaaat cagttaaaac
     9721 gctatcggct accggagcgg gtgcgccagc cgcggcaaac atcatgcgca tggcttcgcg
     9781 ctgatcgacc gccagcatgg caaaaccgcc cgatgcgcgc gtaatgtcgt tgatggtgta
     9841 cttattcatt catttattcc tttatccagt cgttacattt ttactttggc agtcatcccg
     9901 gcactgacac ggacctgttc cagaatggcg gaccagtcct ggcgaccgcg acccgctgcg
     9961 cgcgcctggc tataaacctc ccgtgaggcg gcccccagcg gcattggcac atgcagctgg
    10021 ttggcgacat caagggcgat accaagatcc ttatgggcaa gatcgatcat gaaggcggga
    10081 gaaagatccc cgctgaggac tttgtttggc caggaagtgg tgaagtggcc tttaccggcg
    10141 gcggtaccgc tcatcacctt gacggcaaca tcgaagggaa gattcagggc ttcgcacaaa
    10201 acggcggctt ctgccgaaag cgcattgagc gcgatgctca tgtagttgtt gatgagctta
    10261 acgcggatcc ccatgcccgg accgcccgcg ttgatcaact cactgcccat cgccatcagg
    10321 atcggtgtgg cgcgttcaac ttgttcagcg gtgccgccag ccagcagtaa cagagtaccg
    10381 gtaatggcat ttgcagaagt acggcctacc ggaacatcca tcatgctgaa gcctctggcc
    10441 tgcatatcag caatcaattt atcggtttgc agtgggtgga tggtcgacat atcaatgacc
    10501 agcgcatcgg aagataagct ctcacagaca ccgttttcac cgaacaacac gtgacgcacc
    10561 agatcgccat tcggcaacat ggtaatgata aattcggcac ctttagcggc ctgcgccggg
    10621 ttggcggcgg gagtcgcacc tttgtctacc agatgccgca cagcttcggc gttcacatca
    10681 aagacgcgaa gttgatgccc ttgctgcaat aaattgctcg ccattggcga acccatttgc
    10741 cctaaaccga taaacgcgat tgctgccata accctctcct gaatacagta atgtcacttt
    10801 ttgtcattta tgacatgcct tgcttgtctg tttttgatcg tatttgtaat ttatcgtcaa
    10861 aaaattgaca gtcgtcactt tttaaacaat tggtgaaatt aaaatgaacg catcccaaaa
    10921 tgcttaagga atgaccatga ttcgtgttgc ttgtgtagga attaccgtga tggatcgcat
    10981 ctattacgtg gaaggattgc cgacggagag cggtaaatac gtggcgaaaa attatacgga
    11041 agttggcggc gggccagcgg ctacagcagc agttgcggcg gccagactag gtgcgcaggt
    11101 cgattttatt ggtcgcgtcg gtgacgacga cacaggcaac agcctgctgg cagagctgga
    11161 atcctggggc gttaacaccc gttataccaa acggtataac gaggcgaaat cttcgcaatc
    11221 cgccatcatg gtggatacca aaggcgagcg gataatcatt aactacccca gcccggactt
    11281 gctgcctgac gcagagtggt tggaggaaat tgatttctct cagtgggatg ttgtgctggc
    11341 ggatgtacgc tggcacgaag gtgctaaaaa agccttcacc ctggcccggc aggcgggcgt
    11401 gatgactgtt ttggacgggg acattacgcc gcaggatatc agtgagctgg tggcattaag
    11461 cgatcatgcg gccttttcag aaccgggtct ggcgcgctta acgggggtga aagagatggc
    11521 cagtgcgcta aaacaggcac aaacgctcac aaatggtcat gtctatgtga cccagggcag
    11581 tgcaggctgt gactggctgg agaatggcgg gcgacagcat caaccggcct tcaaagttga
    11641 tgtggtagat accacaggag cgggtgatgt ttttcacggc gcattggcgg tggcgctggc
    11701 aacaggtggg gatttagcgg agtcagtccg cttcgccagc ggagtagcgg cgttgaaatg
    11761 cacgcgtccc ggtggacgag ccgggatccc tgactgtgat caaacccgat cttttttgtc
    11821 actttttgta taaaatgcca gggtgatggt ttttcgagga attttcatga gccttaccga
    11881 actaaccggt aacccgcggc acgaccaact cctcatgctg atcgccgagc gtgggtatat
    11941 gaatattgat gagctggcaa atctgctgga tgtctccacg cagacggtcc gccgggatat
    12001 tcgtaaatta agcgagcaag gactgattac gcgccatcac ggtggcgcgg gtcgggcctc
    12061 cagcgtcgtt aatacggcgt ttgagcagcg tgaggtttcg caaactgaag agaaaaaagc
    12121 gattgccgaa gcggtggcag actatattcc tgatggatcg acaatattta tcaccatcgg
    12181 tacgactgtt gaacatgttg cccgggcgtt acttaaccac aatcatttgc ggataatcac
    12241 caacagcctg cgtgtggcgc atattcttta ccacaacccg cgctttgaag tgatggtgcc
    12301 tggcggaacg ctgcgttccc ataacagtgg gatcattggc ccttcagcgg cgtcctttgt
    12361 ggccgatttt cgcgccgatt atctggtaac aagtgtaggc gcaattgaga gcgatggcgc
    12421 gttgatggag tttgatgtaa acgaagctaa cgtggtgaaa acgatgatgg cgcacgcgag
    12481 aaatattctg ctggtcgccg atcacactaa gtatcatgct tcggcggcgg ttgaaattgg
    12541 taacgtggca caggttaccg cgctctttac cgacgagctg ccgcccgctg cgctaaaatc
    12601 acgcttacaa gacagccaaa ttgaaatcat ccttccccag gaagacacgt agaattttgt
    12661 gaccgttgac ctgccttcat acctggccac atagccaaac ccatcctttc ccgctacagt
    12721 taatttcttg tggcgcgaaa ggaggcaaaa atgctctata tctttgattt aggtaatgtg
    12781 attgtcgata tcgactttaa ccgtgtgctg ggggcctgga gcgatttaac gcgtgttcca
    12841 ctggctacgc ttaagaagag tttccacatg ggcgaggcgt ttcatcagca tgagcgtggg
    12901 gaaattagcg acgaagcgtt cgcagaggcg ctgtgtcatg agatggccct gccgctaagc
    12961 tatgagcagt tctcccacgg ttggcaggcg gtatttgttg cgctacgacc ggaagtgatc
    13021 gccatcatgc ataaactgcg tgagcagggg catcgcgtgg tggtgctttc caatactaac
    13081 cgcctgcata ctaccttctg gccggaggaa tacccggaaa tccgtgatgc tgctgaccat
    13141 atctatctgt cgcaagactt gggtatgcgc aaacctgaag cacgaattta tcagcatgtt
    13201 ttgcaggcag aaggtttttc accagacgat acggtctttt tcgacgataa cgccgataat
    13261 atagaaggag ctaatcagct aggcattact agtattctgg tgaaagataa aaccaccatc
    13321 ccggactatt tcgcgaaggt gttatgctaa aaaccattca ggacaaagcc aggcatcgta
    13381 cccgtccact atgggcctgg ctaaaactac tctggcaacg cattgatgag gacaacatga
    13441 caaccctggc aggtaacctt gcctatgtgt cgttgctctc attagtgccg ctggttgccg
    13501 ttgtttttgc gcttttcgcc gcttttccca tgttttccga cgtcagcatt cagttgcgtc
    13561 actttatttt tgccaacttt ctgcctgcta ctggcgatgt tattcagcgg tatatcgaac
    13621 aatttgttgc caattccaac aaaatgaccg ccgtcggggc gtgcgggctg atcgtcacgg
    13681 cgttattgtt gatgtactcc atcgatagcg cgttgaatac catctggcgc agcaaacgag
    13741 cgcgaccaaa aatttactcg tttgccgtgt actggatgat tttaacgctg gggccgctgc
    13801 tggcaggggc cagtctggcg atcagttcct atctgctctc cctgcgctgg gcgagcgatc
    13861 tcaatactgt catcgacaac gtgctgcgta tttttccgct gctgttgtcg tggatctcct
    13921 tctggttgct gtacagcatt gttcctacca tccgcgtacc taaccgcgac gcgattgtcg
    13981 gcgcgtttgt cgctgcactc ctgttcgaag caggaaagaa aggtttcgcg ctttatatca
    14041 ccatgttccc gtcatatcag ctcatttacg gcgtgctggc ggtgatcccc attctctttg
    14101 tctgggtcta ctggacatgg tgtatcgtct tgcttggcgc ggaaattact gtcactctcg
    14161 gggaataccg caaattaaaa caagctgctg aacaagaaga agacgacgaa ccatgattgc
    14221 attaattcaa cgcgtaaccc gtgccagcgt caccgtggag ggagaagtga cgggcgaaat
    14281 tggcgcggga cttttggtgt tattgggtgt cgaaaaggat gacgacgaac agaaagcaaa
    14341 ccgtctgtgc gagcgtgtgc tcggctaccg catctttagc gatgccgaag gcaagatgaa
    14401 tctcaacgtg caacaggcgg gcggcagtgt actggtggtt tcccagttta ctctcgccgc
    14461 agataccgaa cgggggatgc gcccaagttt ctccaaaggc gcatcaccgg atcgcgcaga
    14521 ggcgttatat gactatttcg tcgaacgctg ccgtcagcaa gagatgaaca cgcaaacagg
    14581 acgcttcgct gcggatatgc aggtatcgct ggtcaatgat ggccccgtga cattctggtt
    14641 gcaggtatga gccagcttcc agggttgtca cgggaaacaa gagagagtat cgctatgtat
    14701 caccttcggg ttccacaaac agaagaagaa ttagagcgtt actatcagtt tcgctgggaa
    14761 atgttgcgta agcccctgca tcaaccgaaa ggttcggaac gcgacgcgtg ggatgcgatg
    14821 gcgcatcacc agatggtcgt cgacgagcag ggtaatctgg tggcggtagg ccgactgtat
    14881 attaatgccg acaatgaagc gtccattcgc tttatggccg ttcatcccga cgtgcaggac
    14941 aaagggttag gaacgctgat ggcgatgacc ctcgaatctg tggcgcgtca ggaaggtgtt
    15001 aagcgcgtga cctgtagcgc ccgcgaagac gcggtggagt ttttcgccaa gctggggttt
    15061 gttaatcagg gagaaatcac cacgccaacc accacgccga ttcgccattt tttgatgatt
    15121 aaacccgttg ccactctgga tgatattttg catcgcggcg actggtgcgc gcagctgcaa
    15181 caggcgtggt atgaacacat cccgctgagt gaaaaaatgg gcgtgcgcat tcagcaatat
    15241 accgggcaaa aatttatcac caccatgccg gaaacaggca atcagaatcc gcatcacacg
    15301 ctgtttgccg ggagtttatt ctcgctggca acgctcaccg gttgggggct tatctggctg
    15361 atgctgcgcg aacgccacct cggcggaacg attattctgg cggatgcgca tatccgctat
    15421 agcaagccga ttagcggcaa acctcatgcg gtagccgacc ttggtgcctt aagcggcgat
    15481 ctcgaccgtc tggcgcgtgg acgaaaagca cgggtgcaga tgcaagtaga aatctttggc
    15541 gacgagacgc cgggtgcagt gtttgaaggc acgtatatcg ttctgcccgc gaagccattt
    15601 ggcccgtatg aagagggcgg gaacgaagaa gagtaggggc gttttacttg actgaaaagg
    15661 ttttcaatct gaaaaccttt tctgggccct ggtccggagt taccttcccg ctctccaggc
    15721 aacatcccgt agcgccgatc gcgcagcctc actgatacca cctaactgaa aaaatccgtg
    15781 gataacgcca aggtagcgtt ggcaggtgca ttgcactcct tgccctgtca tgcggtgata
    15841 caacgcttca ccttcatcgc aaagtgggtc gtattcagcg gtaatgatat gtacaggtgg
    15901 caagccattg aaatcatcgc gccaaagagg gctggcttca ggatgcctgc gttcaatgcc
    15961 tggcaggtac atctcaaagc cgctcagtaa agtgtcgcgt gtgatgatgt aatcgtgacc
    16021 attgcgtatg tagctttcga aatgcgcagt cgcatcaagc atgggataaa ttaagatgag
    16081 ttgtgccggt tgccactcgc cagcacgctt taatcgcaaa gcagttacca gcgccagatg
    16141 tccgcccgca ctgtcaccgg caagagttat ccgttgttta tcaacgccga gtcgttcggc
    16201 gtgttgccag actaattctg cacctcgttg cgcatcatca tgggcggcgg ggaaagtatg
    16261 ttccggtgcc agccgatact ggacggcaat aacccgacat tgcccgtaat aggctaactg
    16321 gcgcagctgg ttgtcgtgag ttgcgaaccc gccgctaaca aaacagccac cgtagtaata
    16381 aattatcgtc gggagtaatg tcggggcatt cagcggtgac actattcgta aggtcatcgc
    16441 ttcaagttcg atagtctgaa tatctacccg cgtttctgtc tcacccgcaa ggacagcgct
    16501 ggcgatatag ccctccctgc gctgcgcaat actttgttga cgcgatgagg ggcgacccgc
    16561 agcgataaac tcttcgacta actctgcaat tcctttttcc agtgccatag tagaactcat
    16621 tttgctgtat gaatgtacag ttttatacac ccgtttttac tggatggata cagggaaatt
    16681 cacgggcgtg aaaaatctgg aaagcgcctc gcaaatgtaa agacaaaccc ggcagagatg
    16741 tggttttgct ggagcactat cagtaagcta gtggtttcaa gggtacgtca atgacgtaca
    16801 aaaaggattg ttactctaag ccaatggcgt ataattatgc tcttcatcga aacggaaatt
    16861 tttactgaag atgttcaaaa actgctgacc gacgatgaat tcagtcgttt tcagtttttc
    16921 ctggccttga atcctgacta tggtgaggta atacctgaaa ctggtgggtt aagaaaggtt
    16981 cgatgggtgt caggaggaaa ggggaaacgt gctggtgtca gggttattta ctttcatcag
    17041 gttaaacatt atgagatcag attactgctt atttatcgta agggtattaa agatgatctg
    17101 tctccccagg aaaaagcaat gctccggttg ttaaatacga ggtggtaaat ggataaggca
    17161 ctttttgagc ggttgactca cagcatggcc cagatgaatg aaattattga aggaacgcga
    17221 cagccttcgc ggacttttga agttgatgct atgaaaatca aagaaatacg ccgcgcttca
    17281 gggttgtcac aatctaaatt tgccgatctt atttctgtaa gcgtagacac gttgcgtaac
    17341 tgggagcagg ggcgacgttc accgaccggg cctgcaaagg ctttgctgcg agcgattgcc
    17401 aatgatccgc aacatgtgct gcaagcactt aaccgttaga ggcatggtta tgccatacag
    17461 aaagcaccag cattcagaac tcctgtgaaa gcggcgtagt gccacctgct caggagtttt
    17521 gctatgaccc gtaatcgtgc tgaccgttgc caccctatga tgcgattaaa aaaactcatc
    17581 gtcgcgccga tgattgacgt caatgctatc ggatgatacc gggggtgttc cggaaggaat
    17641 tccttgtttc ccgaactgtt accaacaaaa ttataacgat gagcaagtta agaccggttg
    17701 gtagcagtac tgaccggtct gtgatggatg attaatttca ccttaaatcc gggtgctgtt
    17761 aggatgctga catttttcgg ctacaccatt cagattatgc aaataaagat ccaatcaaaa
    17821 aataaacatc cctgtatata atatatttat agcacccata tctcatcctg ggcgataacc
    17881 caaccatttt tgattaacaa atgaaacaac tgcaacgttc ttattatttc tggaaaacgt
    17941 ctcgcaaaaa caaaacagca tgcaaaaatc cgcttttttt aaatgatttt tcggcgtaat
    18001 tttcgcacat acattaatga gtaatatatg taaggtattg gtaatggcga tgaatacggt
    18061 ttttcttcat ttatcagaag aggcaattaa acggctgaac aagcttaggg gctggcgtaa
    18121 ggtttcacga tctgcaattt tacgcgaagc ggttgagcaa tatctggagc ggcagcaatt
    18181 tccggtgcgt aaagcaaagg gtggcaggca aaggggggag acagtagttg ttgatgatca
    18241 gtgtaaggag cataaggaat gacaaaaaat ttattattct tgaatataaa aaccagatgc
    18301 ccttattctg gtattaatac aaggctgttt tacttgaact tataataact gcaactgtta
    18361 catcatatct ggaaaacgcc tcgcgaaata cgagagattt tgcgggaata gcaggtgtcg
    18421 tcatacccta tgaactgtaa tccgggcgac cagcgccacc cggaaaacgt cagagattac
    18481 tccccttcac ccggaaacag gaacgggttg atggaactac gggcatagcc ttcttgctcc
    18541 attcgcgcgt ccagtaccag agaggcgagg tcatctgcca cggcttcaac tttcggttct
    18601 ttttcctgat aaagaatctt caggtaagtg ccgcagtcat cgcagctttc ggctttaatc
    18661 gcggcctgtt cgtcatccag cgaccagtaa tgcagtttgc cgctttgttc acagttgctg
    18721 cattttacgc gtactacgtg ccattcagtt tcacacaggt tgcagtgcag gtaacgcagc
    18781 ccctgagtgg tgccaatttg caccatgctg gacaccggca tagaaccaca aaccgggcaa
    18841 tattgacgtt gttcgccata ttccgcacgc gctttgccgg ggatcagatt ggccatctgc
    18901 gcccagtaga gcgacagtgc agcccagata aacggcgctt tatcgctgct gacggacgag
    18961 aaatcagagg caaacagtgc gctggccata tcttccagct cctgagtcga tgccttctcc
    19021 agattctcaa tcactgccag cgccgggccg ctcatttcag gtttcagctc agcaatcagc
    19081 gccatcagca gcttttgcca gtgcttatca cgcggcagaa cgtgaatatc cagcgggggc
    19141 ttgccttgtg cgctggcttc tttaatgcgc gtggtcagat ccatctccag cggatggtcg
    19201 tacagcacca cttcctgggc gtgggcgata agcgcagcaa agcgcaggta atcacccagc
    19261 ggattatttt ctgccagctc gcgcagacgc tcggcgcggc ggttgtataa attcttgagc
    19321 cgagggaaca ataacggcgg aatcatatcc gccgtacgtt tctcgctcga acccagctca
    19381 tcttgcggga ttatgcgaat actcattcag ctttcttttc cgttgtcttg cggacctcac
    19441 ggtaccagcg cgggtgatgt ttcttcgccc aggcgctggt aacccatcct tccaccatgg
    19501 cggtaatcgt gcctttcacc caaagggcgg cgtagatatg caccatgata accacaatta
    19561 acgccactgc ggcaaatgaa tgcagcatta acgcgaatcg gatcaccggg attgagaaag
    19621 caggtgcaaa ataaggacgc cagataatca cgccgctcac cagcagcaga accaggaaaa
    19681 taatcgccgc ccagaaaacg catttctgac cgaagttata acgcccggtg tcacctactt
    19741 cctcgttgac gacgatctta cgaatattct tcgcccaaaa gatatcatcc cgattgatta
    19801 ggttgtgatg ccagtaacgg aaaaacatga tgatgaacga ggcaaacata accacgccga
    19861 caaacgggtg cagaatgcgc gccagctgcg gtgtgcccat gatttgcatc aaccagttga
    19921 aggacgggaa caaaaagccc agcccgctca ccgccgccag gatgaagcag aaggcggtga
    19981 tccagtggtt gatacgttcc ggcgcggtgt agcgcacgat ggtgtcacgt cgtttcattt
    20041 gcgctcctcg tctttctctt cgtgcagatt attctcttcc tcatccgcac ggttcggacc
    20101 gacacccacg tagtggaaga tactggccgc aaaggtagcc gcaaagccaa cagccgcgag
    20161 cggtttccag atgcctttcc agaatttcac ggtttcgctg atttccgggt tctccggcaa
    20221 gccatgatac agatttggct tgtcagcatg gtgcagcacg tacataacat gtgtaccacc
    20281 gacgcctgcc gggtcgtaca aacccgcatt gtcgtaacca cgggttttca gctccgccac
    20341 gcgctcgctc gccagcgttt tcatcgactc tttcgtaccg aagtgaatcg cgcccgttgg
    20401 gcaggtcttc acgcaggccg gttcttgccc aaccaccacg cggtcaacgc acaacgtaca
    20461 tttgtagacg cggttgtctt ccgggttgag gcgcggaatg tcgaacggac agcccgcaat
    20521 gcaataaccg cagccgatgc actgctcgga ctggaagtcg acgataccgt tggcatactg
    20581 aataattgcc ccttccgccg ggcacgcttt caggcagcct ggatcggaac agtgcataca
    20641 gccgtctttg cggatcagcc attccagttt gtcgttctgc tccacttccg agaatcgcat
    20701 caccgtccac gatttggcac ttaaatcatt ggggttgtcg tacaccccaa tgttattgcc
    20761 gacggtatcg cgaatgtcgt tccactctga acacgccacc tgacaggctt tacagccgat
    20821 acaggtggta acgtcgatga gtttcgccac ttcttcctgg aagtcccgcg cctgaggcgc
    20881 gggggtcaga ccgttagtcg cggaacgacg aatgatatct tgcgattgat aagccatatg
    20941 tcgtctccgt tacacctttt ccacattcac aaggaaggac ttaaactccg gcgtctgcgt
    21001 gttcgcatca cccacgaatg gcgttaacgt attggcaata aagccttttt tcgcaacgcc
    21061 ttcatagccc cagtgaatcg gaataccgat ggtatcgata tctttgccgt tcgctttcag
    21121 cgtgcgaata cgtttggtca ccaccgcttt ggctttgata tagccacggt tggaggagac
    21181 tttcacagta tcgccctggg caatgccaag tttattcgcc agcgactccc cgatttccac
    21241 aaactgctct ggttgcaaaa tcgcattcaa cagcgcgtgt ttggtccagt agtggaagtg
    21301 ctcggtcaga cgataggtgg ttccgacata cgggaactta tcggctttac ccaatgcttc
    21361 ggcgtcgtct ttaaagatac gcgcagccgg gttcgagata acgtttggat gcagcgggtt
    21421 agttcccagc ggcgtttcaa acggctcgta gtgttccggg aacggacctt ccgccatctt
    21481 atcgagggca aacagacgtc ccatgccttc ctgctgcatg ataaacggcc ctacgccgct
    21541 gcccggaggc gctgcgctgt agtccggaat atcccagccg gtccacttag tgccgtccca
    21601 tttcagcaac tgacgcttcg gatcccatgg gttaccctgc ggatctgcgg aggcgcggtt
    21661 atacagaatg cggcggttaa gcggccatgc ccatgcccag cccagcgtgt taccgaggcc
    21721 agacggatcg gcgttatcac gacgcgccat ctggttacct tctggcgtcc agctaccggc
    21781 gaaaatccag cagccacagg aggtcgtacc gtcatcgcgc agttgggcga acgagctaag
    21841 ttgttggcct ttcttgacga taaccgcacc ggttgccgga tcggtaatat cggccagcgc
    21901 cttaccgttg ctctccatcg ccacttcttc cgacttcggc tcatgcggaa tggcgtagtt
    21961 ccaggtcata ttcagcacct ggtccgggtt tgcgccaccc tgttcggcat acatcttgcg
    22021 caagcgcagg aagataccgg agaggatctc gccatcagtc agcgcaatcc ctggggcgtc
    22081 cgcacctttc cagtgccact gtaaccagcg accggagtta acgattgaac cgttctcttc
    22141 tgcgaagcaa gtcgatggca gacggaacac ttcggtctgg atcttcgacg agtcaacttc
    22201 gttcagctca ccgtggttct gccagaagtt agaggtttca gtgttcagcg ggtcgatggt
    22261 gacgaggaac ttcagtttcg acagacagcc gatcactttg tttttgttcg ggaatgaggc
    22321 aacagggtta aagccctggc agatatagcc attgaccttg ccctctttca tcatctcgaa
    22381 gtattgcagg acgtcgtagc ctttatccca cttcggcaac cagtcaaagc cccagttatt
    22441 ttccgccgtc gctttatcac caaagaaggc cttcatcatg gagacgaaga atttcgggta
    22501 attgccccag tagttaacct ggccttccag cagtggtttc ggcgtgttgg cggtaaggta
    22561 agtttgcaga tcggtctgct tctcgcttgg caacgtcatg taacctggca gactctgcga
    22621 cagcagcccc aggtcggtca gcccctgaat attggagtga ccgcgcaggg cgttaacgcc
    22681 gccgccagcc atccccatat tgccgagcag cagctggatc atcgccatcg tacgaatgtt
    22741 ttgcgcacca atggagtgtt gcgtccagcc gagggcgtag aggaacgacg ctgttttatc
    22801 gtgagcactg gtttcggcga tgtattcgca gactttcagg aacgcgtctt ttggcgtacc
    22861 gcagatgttt tcaaccacat ctggcgtata acgggaaacg tgctgtttca gcaagttcca
    22921 cacgcaacgt ggatgttgca gcgtggtatc gcgtttggcg aagccgtttt cgtccagttc
    22981 gtaagtccag gaggatttat cgtacttgcg tttttccgcg tcgtagccgg tgaacaggcc
    23041 atcttcaaag ccgtaatcct cacgcacgat caggctggcg ttggtatagg cttcggtgta
    23101 ttcgcggttg aatttttcat tgttcagcag gtacagcaat acgcctgaca ggaaagcaat
    23161 gtcagtcccg gaacgaatag gggcatagta gtcagccacc gccgccgtac gtgtaaagcg
    23221 aggatcgatc acaatcagct tcgcgccgtt gtgaattttg gcttccatcg cccagcggaa
    23281 cccgaccggg tgagcttcag cggcgttacc gcccatcacc acgacgaggt tggcattctt
    23341 gatgtcgacc cagtggttgg tcatcgcacc gcgaccaaat gttggagcaa gacttgctac
    23401 cgttggtccg tgtcagacac gcgcctggtt gtcgaccgcg agcataccca gcgcgcggga
    23461 gaatttttgc gttaaatagc cggtttcgtt actcgacgcg gaagcacaca gcatcccggt
    23521 ggagagccag cggttaacag tcacgccttc ggcgttttgc gcaatgtagt tcgcatcgcg
    23581 gtcttctttc atcagtttgg cgatgcgatc aaacgcctct tcccaactga tttgttgcca
    23641 tttatcagaa cctggcgcac ggtattccgg aaacttcagg cggctttcgg agtggatgaa
    23701 atccaccagg ccagcgcctt tcggacaaag tgctccgcgg ttgaccgggt gatccgggtc
    23761 accttcgata tggaagatag atgctttggc gttttttgct ccgtcaccga ggctgtacat
    23821 caacagccca cagcctacgg aacaataggt gcaggtatta cgggtttcgc gggtgcgcag
    23881 cagtttatac tgccgggttt ccgcgagtgc tacgctgggt gcaaaaccca gtgccgctgc
    23941 cgtggtgcct gccataccgc cagcgcagat cttaaagaac tgccttctgc tgacctgcat
    24001 ggattgctcc ttgtttcgac attgtcacgt cccatttaca ttcgcttgct gcgtgtgcag
    24061 ggagtgggag ttatttttct ttgcggaagg ggccgcaaag gtccagaatt ggctcaattt
    24121 ccctccatcc aggaagggtt tgtaacagaa taccataatg ttggtgtgtg tgttcttatc
    24181 tggttaagag aaagtgaaaa aaacacagca aaaagaaatc gaaaatgtga caagtgtcac
    24241 aggtgttcgt caaattgagt tatggcggcg tgatgattta caacacccac ggttagatga
    24301 ggtggcggaa gaggttcccg ttgcgctggt ctacaacggc atttcgcatg tagtgatgat
    24361 ggcgtcaccc aaagaccttg agtactttgc gctcggtttt tcgctttccg aggggattat
    24421 cgaaagtccg cgcgatatct tcggtatgga tgtcgttcct tcctgtaatg gtctggaagt
    24481 gcaaattgag ctttccagcc gccgctttat ggggttgaag gagcgtcgcc gggcactggc
    24541 gggacgtacg ggatgtggcg tgtgcggcgt ggagcaactt aatgacatcg gaaaaccggt
    24601 gcagccgcta ccgttcaccc agacgtttga tctcaacaaa ctggatgatg cattacgtca
    24661 tctcaatgat tttcagccag tggggcaact gaccggttgt actcacgccg ccgcctggat
    24721 gttgccatct ggcgaactgg tcggcgggca tgaagacgtg ggtcgccatg tggcgctgga
    24781 caaactgtta ggccgccggt cacaagaagg ggaaagctgg cagcaaggtg cggtgctggt
    24841 ttccagccgt gccagttatg aaatggtgca aaagtcagcg atgtgtggcg tagagatttt
    24901 gtttgcggtg tctgccgcga ccacgcttgc cgtagaagtg gctgagcgct gtaatctgac
    24961 actggtaggt ttttgtaaac cgggtcgggc aacggtttat acccatccgc agcgtttgag
    25021 caattaatta aaataagt
//
LOCUS       DADXDL010000069        24243 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.069, whole genome shotgun sequence.
ACCESSION   DADXDL010000069 DADXDL010000000
VERSION     DADXDL010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24243)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24243)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24243
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.069"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(51..1700)
                     /gene="pgi"
                     /locus_tag="IRB70_003294"
     CDS             complement(51..1700)
                     /gene="pgi"
                     /locus_tag="IRB70_003294"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBC0633170.1"
                     /translation="MKNINPTQTAAWQALQKHFDEMKDVTIADLFAKDGDRFSKFSAT
                     FDDQMLVDYSKNRITEETLAKLQDLAKECDLAGAIKSMFSGEKINRTENRAVLHVALR
                     NRSNTPILVDGKDVMPEVNAVLEKMKTFSEAIISGEWKGYTGKAITDVVNIGIGGSDL
                     GPYMVTEALRPYKNHLNMHFVSNVDGTHIAEVLKKVNPETTLFLVASKTFTTQETMTN
                     AHSARDWFLKAASDEKHVAKHFAALSTNAKAVGEFGIDTANMFEFWDWVGGRYSLWSA
                     IGLSIVLSIGFDNFVELLSGAHAMDKHFSTTPAEKNLPVLLALIGIWYNNFFGAETEA
                     ILPYDQYMHRFAAYFQQGNMESNGKYVDRNGKVVDYQTGPIIWGEPGTNGQHAFYQLI
                     HQGTKMVPCDFIAPAITHNPLSDHHQKLLSNFFAQTEALAFGKSREVVEQEYRDQGKD
                     PATLDYVVPFKVFEGNRPTNSILLREITPFSLGALIALYEHKIFTQGVILNIFTFDQW
                     GVELGKQLANRILPELKDDKEISSHDSSTNGLINRYKAWRG"
     gene            2225..3574
                     /gene="lysC"
                     /locus_tag="IRB70_003295"
     CDS             2225..3574
                     /gene="lysC"
                     /locus_tag="IRB70_003295"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine-sensitive aspartokinase 3"
                     /protein_id="HBC0633171.1"
                     /translation="MSEIVVSKFGGTSVADFDAMNRSADIVLSDANVRLVVLSASAGI
                     TNLLVALAEGLEPGERFEKLDAIRNIQFAILERLRYPNVIREEIERLLENITVLAEAA
                     ALATSPALTDELVSHGELMSTLLFVEILRERDVQAQWFDVRKVMRTNDRFGRAEPDVA
                     ALAELAALQLLPRLNEGLVITQGFIGSENKGRTTTLGRGGSDYTAALLAEALHATRVD
                     IWTDVPGIYTTDPRVVSAAKRIDEIAFAEAAEMATFGAKVLHPATLLPAVRSDIPVFV
                     GSSKDPRAGGTLVCNKTENPPLFRALALRRNQTLLTLHSLNMLHSRGFLAEVFGILAR
                     HNISVDLITTSEVSVALTLDTTGSTSTGDTLLTQSLLMELSALCRVEVEEGLALVALI
                     GNDLSKACGVGKEVFGVLEPFNIRMICYGASSHNLCFLVPGEDAEQVVQKLHFNLFE"
     gene            complement(3629..3976)
                     /locus_tag="IRB70_003296"
     CDS             complement(3629..3976)
                     /locus_tag="IRB70_003296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBC0633172.1"
                     /translation="MIRKSKEMARTPEIINDLAFHASQVLIESINLDSSSAENVGFAI
                     ADRMMRNWGGQSIYFPKGISGRASERDYQIYSECDGRNYAELAKKYNLTLQWIYKIVK
                     RVHAEKQQRRSNS"
     gene            4514..4801
                     /locus_tag="IRB70_003297"
     CDS             4514..4801
                     /locus_tag="IRB70_003297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin"
                     /protein_id="HBC0633173.1"
                     /translation="MKKVTFPRLSGWLVASAALFVVIGWTSSAQIPVVIYKLSLVSLS
                     AVLGYWLDRSLFPWARPDSFSPWKEPRCCAAAMIRRAIIVAAVCLSVALGL"
     gene            4804..5409
                     /locus_tag="IRB70_003298"
     CDS             4804..5409
                     /locus_tag="IRB70_003298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001402756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBC0633174.1"
                     /translation="MWLKYIASMIIFVLFPLNASEPPRASLAWRNELIRTAREVWGLN
                     APVADFAGQLHQESAWQPMVRSPVGAQGMAQFMPATATWISQLYPQLRENKPYNPTWA
                     IRALVQYDQHLWKNISAKNDCQRMAFTLSAYNGGQGWVNRDKKLAASKGLDATSWFGH
                     VEQVNAGRSATNWRENRRYPKMILYQHAARYLLWGQASCLH"
     gene            5422..5736
                     /locus_tag="IRB70_003299"
     CDS             5422..5736
                     /locus_tag="IRB70_003299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633175.1"
                     /translation="MKLSIDFWEVISLMLSFVGLMFAAGKLLLAQIEKRLNERFESLE
                     NARRESETSWSKLEREFLEFRAELPLHYVRREDYLRGQAVLEAKLDALYSKIELLQRG
                     SY"
     gene            5881..6336
                     /locus_tag="IRB70_003300"
     CDS             5881..6336
                     /locus_tag="IRB70_003300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000404768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633176.1"
                     /translation="MEILSVMNSVVTRLREHNSEMDIFISSKDAQKYIPQTQRVAVII
                     NYSGSVFATPESSNAIVQQQILRLTATVIVGKNCDALNALDHIRSALGGLPLPDCDRL
                     LWLEKEINTGESGGFCRYILEMATSSLFIAEQESTDLPLLTEVNYEETE"
     gene            6333..6530
                     /locus_tag="IRB70_003301"
     CDS             6333..6530
                     /locus_tag="IRB70_003301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633177.1"
                     /translation="MKYIYNGPASGVTLADGQEILLWPNSEIDLPEDNEWVMTMIARN
                     HLTPVITQEEQNNVEEIVHGS"
     gene            6520..7944
                     /locus_tag="IRB70_003302"
     CDS             6520..7944
                     /locus_tag="IRB70_003302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail sheath family protein"
                     /protein_id="HBC0633178.1"
                     /translation="MAANYLHGVETIEIETGPRPVKAVKSAVIALIGTSPCGPVNKPT
                     LCLSESDAAQFGSTQANFTIPQALKAIYDHGAGTVVVINVLDPAKHGSNISNESITFD
                     ANNQAKLAHRNVRNVVLKPSSSNSSTFNTAAFSVDEQTGIITRKGADIPPGAKVCAYY
                     SWCDPTKVTAADIIGTVNTAGDRTGMKLLQDTYNLYGFYAKILLAPVFCTQKSVTTEL
                     IAQAEKLGAITYIDAPIGTTFQQVLAGRGSQGAINFNTSSDRARLCYPHVKVYDGITN
                     QEILEPLSSRAAGLRAKVDLEKGFWWSNSNQEIQGITGIERSLSAMIDDPQSEVNQLN
                     ENGITTIFNSYGSGLRLWGNRTAAWPTVTHMRNFENVRRTGDVINESIRYFSQQYIDM
                     PINQALIDALTESVNTWGRKLIADGALLGFECWYDPARNSPAELSAGHLLLSYKFTPP
                     PPLERLTFETEITSEYLVSLESNS"
     gene            7944..8468
                     /locus_tag="IRB70_003303"
     CDS             7944..8468
                     /locus_tag="IRB70_003303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major tail tube protein"
                     /protein_id="HBC0633179.1"
                     /translation="MAGKIQINRITNANIYLDGNNLLGRATEIKLPDVSLIMQEHKAL
                     GMVGKIELPAGFDKLEGEIKWNSFYQDVMRKTANPWQAVALQCRSSIDCYNSQGKANQ
                     LALVTHLTVMFKKNPLGTFKQNENPEFSSAFGCTYIKQVVDGETLLELDYMANIFRVN
                     GVDQLSTYRNNIGG"
     gene            8519..8836
                     /locus_tag="IRB70_003304"
     CDS             8519..8836
                     /locus_tag="IRB70_003304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein"
                     /protein_id="HBC0633180.1"
                     /translation="MKEHYILQFPFTSAAGNNIDTLQLRRLKVKDMRNARRISEKPEE
                     WDEPLMAAMTGLVPEDLAEMDLLDYQALQKRFQSMLTVVTESSPAMAGNGATGEMVSL
                     SAQ"
     gene            8796..8924
                     /locus_tag="IRB70_003305"
     CDS             8796..8924
                     /locus_tag="IRB70_003305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015674804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GpE family phage tail protein"
                     /protein_id="HBC0633181.1"
                     /translation="MALLARWFRFPPSEIDALTVDDFSNWLDEASAQIKIEYDSQT"
     gene            9026..11401
                     /locus_tag="IRB70_003306"
     CDS             9026..11401
                     /locus_tag="IRB70_003306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001262480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBC0633182.1"
                     /translation="MANDIITQLQARNETLTQAIARYGSLNARTLLTLSTQQATVIKL
                     TQQLADSALRLEENSRSRANLMEKTQTFAGQFSKVFNVEAPDWKLPYEFQDNMVNMAT
                     KGGMNATTRETLSLNLRDWSMDFNQQQTTLQNAAQTLIEGNLSSMQDLNRYMPEIAKA
                     ATATRESAETWANAALATHDRLNIAPENFHAAQNMMYGISKSGGPAIAEQTQWIEKFA
                     GKTGAQGLEGMAELTAAMQIAMKNGASASAAAENFDHFLQTTFSKKTDSWFASQGVDL
                     QGSLLEHQQNGMGVSEAMTHIVQMQLEKMNPAILDTFKRTMQIEDLSARSNALQSMVS
                     QFNLGEMFGDVQTVEFLAPMLANMEEYRQLKASAMQATSKNLINADFSAQMASPIEQT
                     KALQLALNDLWLSIGLQLMPAIGELAQSLTTVIRQFSAWLREHPALVQNIAKIVGAVW
                     LFNGALNVLKLGANLITSPFIRLVDIFLKVKASLALTGGASKMLSAVKSLGGGAKWLM
                     QLLGRGLIGALKQVGQTVFWLGRVLLMNPIGLVITAIAGAAYLICRNWEPISRFFSTI
                     WQRITTAFDGGIAGICRLILDWSPLELFYSAFSSVMNWFGVEMPASFSEFGSNLLGSL
                     VDGIMNAFPALKGIIDQVKNAIPDWLKTTMGISTEGSATAITSTTNTASVSPATVVPG
                     VAGAILTPPVGKQLAPSGKTATPSSAPAAKNTAAKPVSASLPGKSVTKPATLPSRSSG
                     KVQVNFSPQITVQGNGQNTTKEIQNVLTMSKRELERMINDVMAQQQRRGYA"
     gene            11401..12354
                     /locus_tag="IRB70_003307"
     CDS             11401..12354
                     /locus_tag="IRB70_003307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000271437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633183.1"
                     /translation="MYAVLGEIEFKVVTFWDGFKSTMGVDYATHARIEGKPGVQFIGD
                     KLDMLALEFSLHSQFCQPTTELNRLREAMLAHKAMALVFGNGDYRGWFVITELTATHQ
                     HTDPWGNVIAQNGTMSLQEYTGDPKNPLLPPAITTQEPNIEEKASDFPDKVESWFDQI
                     LNAIEEGMRKAKEMLDELTQAIEDIKKTVAKVKAMIKEAKALKEKCEKIITSLKKTID
                     AIETLFKQPMDLQTLAGLPKALSAQIKTLLGNMPGIRDCANDASTLVDHAQALFDDIT
                     SDIAEATFDKAATLVDQARTTVQQTTPTVSQLAAATITRIW"
     gene            12354..12563
                     /locus_tag="IRB70_003308"
     CDS             12354..12563
                     /locus_tag="IRB70_003308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail protein X"
                     /protein_id="HBC0633184.1"
                     /translation="MRYLEHITTDGERWDNLAWHYYGDALAYERIIAANPHVAIYPVL
                     PSGIQLIIPVISVNKTLSEIPPWLR"
     gene            12551..13591
                     /locus_tag="IRB70_003309"
     CDS             12551..13591
                     /locus_tag="IRB70_003309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage late control D family protein"
                     /protein_id="HBC0633185.1"
                     /translation="MAEISVTGGVFATLTPIFTLWYGHKDITYDITPYVTSISYHDSI
                     KNESDTIAITLDDTDGRWIKEWYPGKGDTLALHMGYQGEKLLDCGQYIIDKIDISAPP
                     STVNIDGIATSVNQALRTRNSQGFEETTLSAIASRIAQTHGLKLVGKIEPLTIDRVTQ
                     YGETDVGFLKRLASEYGYAVKVTTKELIFSHLPTLRCLAPVKKIDRKDVSHFTFKDTI
                     NRIYKNATVQHQNSKKKELVIYTHNSQQKPSARGVGTSADTLKLNSRATDVGAAQAKA
                     NAALDSHNEYQQTGTLTMMGCPELTAGNKIELTDFGVLSGQWLIDKSTHSFVRSGYTT
                     EIDVSRGPATSQ"
     gene            13601..14302
                     /locus_tag="IRB70_003310"
     CDS             13601..14302
                     /locus_tag="IRB70_003310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate assembly protein V"
                     /protein_id="HBC0633186.1"
                     /translation="MKGVTRQTGIISDIDETSVRVRVTLPECDNLKSNWLAVLQRNSQ
                     DNKDYWLPDMGEQVEVLLDNNGEDGVVLGAVYSTVDTAPVASRDKRYVQFSDGAAFEY
                     DRSTHQLTINGGIEKIVIEVINGTCLTSPNVEIKAQQVTVTSDTVDVKATDVSIDATK
                     VEVKAAAVTVDAPMSTFTGNVTVMKKLTWLGGMAGSGGIGNAATITGNVNVIGNVQAS
                     GALQDSGGNSNHHSH"
     gene            14401..14760
                     /locus_tag="IRB70_003311"
     CDS             14401..14760
                     /locus_tag="IRB70_003311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GPW/gp25 family protein"
                     /protein_id="HBC0633187.1"
                     /translation="MNTKTRPSTLHWQPALLRPEEYVCGLDDIHQAIHIILRTPRGSD
                     PHRPLFGSNLWHYIDYPIERAIPHVVRESVEAIRQWEPRCRLLKVTPVIDGEHLTLRV
                     QWRAADGVINSTEVLWR"
     gene            14751..15866
                     /locus_tag="IRB70_003312"
     CDS             14751..15866
                     /locus_tag="IRB70_003312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="baseplate J/gp47 family protein"
                     /protein_id="HBC0633188.1"
                     /translation="MAIAEPNFIDRDPAQITSEMIAQYEDASGKKLYPAQAERLLIDL
                     FAYRENLVRIAIQEAAKQNLVAYSRAPMLDYLGELVGVHRLPAQPAKTTLQFSVVSAY
                     TSNILIPQGTRASASDSVMFATDEDVLLPAWSLHIAVPATSLAAGEQGNGWQPAQISA
                     LVDRIGHYDINVTNLTASTGGCGEESDDALRQRIQLAPESFSNAGSYGAYRFHTLSVS
                     QSIIDVAVLGPDEGLPEGCVEIYPLTLNGLPGIELLAQIEQEVSKEKKRPLTDKVSAK
                     CALRVPYEIRAQLTLFTTADQETTLAAARKAISLWTQQRQKHLGQDIVPNQIIKVLQV
                     DGVYDVALNLPTKRILQAHEWAECTAIDVTIAGVSDG"
     gene            15859..16575
                     /locus_tag="IRB70_003313"
     CDS             15859..16575
                     /locus_tag="IRB70_003313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein I"
                     /protein_id="HBC0633189.1"
                     /translation="MDKLLPPPPLASDERFSILANIAAERFAQLDLTALMVYLVDLVD
                     ASALPALAEQFHVQGLEGWLFTTDEREKRELIKQAIELHKYKGTIWAVRRVLEILSLP
                     GTISEWFEYGGRAYFFKVDITLEEKGLNEDEFNALITLIHEYKNVRSKLESIVIWLIN
                     RSPIPVIGSAMQGGEVITVLPPVAESLSQSSGIFLATGYCVEEYIQLLPYQPDRLTQS
                     QPMKVGTGYWSTEIMSVYPE"
     gene            16578..18188
                     /locus_tag="IRB70_003314"
     CDS             16578..18188
                     /locus_tag="IRB70_003314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000135569.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633190.1"
                     /translation="MASEFFTILTAAGKAKIASALAEQKQIRLQTMVVGDGNGKYIEP
                     TESQTKVVHEVWRGQLNTLKIAPDNPAWVIAEAIIPEQVGGWYVREVGLLDTDGTMVA
                     IGKFPETYKPRLPAGASKQIVIRAVMEVTNADAVTLLIDPSVVVATREYVDDALKTHQ
                     QSRNHPDATLTQKGFTQLSNATNSDDETKAATPKAVKTAYDLANSKAATSHNHAWNQI
                     TGIPDGTLTQKGVVKLNNTTNSTSTTEAATPSAVKAAMDKAIAAAPSSHTHAWGQITG
                     IPDGTLTQKGVVKLNNATNSTSTTEAATPNAVKAAMDKAIAAESCPVGMPIPWPSDSV
                     PSGYALMTGQTFNKTSYPKLAIAYPSGVIPDMRGWIIKGKPSSGRAILSTELDGVKSH
                     NHTGSISSTDLGTKSVSSIDLGTKNTQSFNHGIKTTNTAGAHSHDSGSGESSEGGKPR
                     YGTRDNTTNNFGSGESDHDNYKFNTSTDGEHAHSVNVGSHSHSVILGSHNHSIALGSH
                     NHSLTINNTGNTENTVKNIAFNYIVRLA"
     gene            18185..18892
                     /locus_tag="IRB70_003315"
     CDS             18185..18892
                     /locus_tag="IRB70_003315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012602631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4376 domain-containing protein"
                     /protein_id="HBC0633191.1"
                     /translation="MNTFTFSDEAQILTVYNFSQDSQEYIGESDAYIAPNTGLPNYCT
                     LISPPEKVPGFTPVWENETWRLIEDHRGQTVYNKVDGSQLIIQELGQLPENVTVISPT
                     GSFERWDGEKWQPSITDAKEAKYSAIKNQRDAITTDYIIINNHHFHSDTNSRIQQLSL
                     TKMGAEKKIPPGLMWKTKNNGLIELTNEIAAQFESVTMDHDMRLFANAQRHIAAVEAL
                     DDIQAVLDYDYSTGWQP"
     gene            18889..19344
                     /locus_tag="IRB70_003316"
     CDS             18889..19344
                     /locus_tag="IRB70_003316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000047949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633192.1"
                     /translation="MSKTTVWLACYKGRTEHRGIARLADWLTRKITRGHYSHCELAVK
                     HGEKRYLCYSASLRDRGVRGKIMPLPADKWDMLPLQASLQDVETFFRKHDGKKYDWRG
                     ALGIITGNKEQRDRLFCSEFCAEFLQLKESWRYSPNHLYALVSSWQYQQ"
     gene            complement(19358..20149)
                     /locus_tag="IRB70_003317"
     CDS             complement(19358..20149)
                     /locus_tag="IRB70_003317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBC0633193.1"
                     /translation="MPLNGVSAAMRERVSQQLKEIERRYGVKVLYACESGSRGWGFAS
                     PDSDYDVRFLYVHPLEWYLRVESPRDVIELPIDDELDVSGWEWRKALGLLKGANPTLI
                     EWLDSPVVYQQDEETITALKAMVPMWFSSLRARWHYYSMAQKNFRGYLQGDEVRLKKY
                     FYVLRPLLAVRWVEAGKGVPPMRFAELLAGSELDAALRAEIDELLERKQRASEAEYGL
                     RRPLLHAFIRAELARGEIPPILPDSRDGDVRELDNLLYQTVMCRA"
     gene            complement(20155..21282)
                     /locus_tag="IRB70_003318"
     CDS             complement(20155..21282)
                     /locus_tag="IRB70_003318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000592028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="slipin family protein"
                     /protein_id="HBC0633194.1"
                     /translation="MIKKISVRKDQLALLSRNGDYYKVLHAGEHLLPWLNTPEVLLIT
                     LDGSEVPDVLADYLRRFQPEWVERYCVVADLSETEAGALYMDGILLEILPPSTRRLYW
                     RVEDDLTLVRMSTQQVQVQTEVMNAVLQPRRKGAVKGRDAILTVQVPAWHVGVLKIDG
                     KTQALLPPGLTAYWKINHLVEAEVVDTRLQVLEVSGQEILTKDKVNLRINLAANWRYS
                     DVLLAFSQLTKPIDHLYRELQFALREAVGTRTLDELLEDKQVIDDVVSEQVKSRMLPF
                     GMEIASLGVKDIVLPGDMKNILAQLVEAEKSAQANVIRRREETAATRSLLNTAKVMEN
                     NPVALRLKELETLERVAERIDNISVFGGLDQVLHGLVNIKG"
     gene            21811..22083
                     /locus_tag="IRB70_003319"
     CDS             21811..22083
                     /locus_tag="IRB70_003319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3811 domain-containing protein"
                     /protein_id="HBC0633195.1"
                     /translation="MALPRITQKEMTEREQRELKTLLDRARIAHGRVLTNSETNSIKK
                     EYIDKLMVEREAEAKKARQLKKKQAYKPDPEASFSWSANTSTRGRR"
     gene            complement(22084..22956)
                     /gene="rluF"
                     /locus_tag="IRB70_003320"
     CDS             complement(22084..22956)
                     /gene="rluF"
                     /locus_tag="IRB70_003320"
                     /EC_number="5.4.99.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2604) synthase RluF"
                     /protein_id="HBC0633196.1"
                     /translation="MLPDSSVRLNKYISESGICSRREADRYIEQGNVFLNGKRATIGD
                     QVKPGDVVKVNGQLIEPREAEDLVLIALNKPVGIVSTTEDGERDNIVDFVNHSKRVFP
                     IGRLDKDSQGLIFLTNHGDLVNKILRAGNDHEKEYLVTVDKPITDEFIRGMGAGVPIL
                     GTVTKKCKVKKEAPFVFRITLVQGLNRQIRRMCEHFGYEVKKLERTRIMNVSLSGIPL
                     GEWRDLTDDELIDLFKLIENSSSEAKPKAKAKPKTVGIKRPVVKMEKTVEKGGRPASN
                     GKRFTSPGRKKKGR"
     gene            23304..>24243
                     /locus_tag="IRB70_003321"
     CDS             23304..>24243
                     /locus_tag="IRB70_003321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding transcriptional regulator"
                     /protein_id="HBC0633197.1"
                     /translation="MENSDDIRLIVKIAQLYYEQDMTQAQIARELGIYRTTISRLLKR
                     GRDQGIVTIAINYDYNENLWLEQQLKQKFGLKDVVVVSGNDEDEETQLAMMGLHGAQL
                     LDRLLEPGDIVGFSWGRAVSALVENLPQAGQSRQLICVPIIGGPSGKLESRYHVNTLT
                     YSAAAKLKGESHLADFPALLDNPLIRNGIMQSQHFKTISAYWDNLDVALVGIGSPAIR
                     DGANWHAFYGGEESDDLNARQVAGDICSRFFDIHGAMVETNMSEKTLSIEMNKLKQAR
                     YSIGIAMSEEKYSGIVGALRGKYINCLVTNSSTAELL"
BASE COUNT         6435 a         6032 c         5880 g         5896 t
ORIGIN      
        1 tgataaaaca atgccgactt atagtcggca ttgttattaa ggtttttaaa ttaaccgcgc
       61 cacgctttat agcggttaat cagaccattg gtcgagctat cgtggctgct gatttctttg
      121 tcatctttca gctctggcag aatacggttc gccagctgtt tacccagttc cacgccccac
      181 tggtcgaagg tgaagatgtt caggatcacg ccctgagtaa agattttgtg ctcatacagc
      241 gcaatcaacg cacccaggct gaacggagtg atttcacgca gcaggatgga gttggtcggg
      301 cggttacctt cgaacacttt gaacggcacc acgtagtcaa gcgttgccgg atctttaccc
      361 tgatcgcgat attcctgctc aaccacttcg cgggatttac caaacgccag cgcttcggtc
      421 tgagcaaaga agttagacag cagtttctgg tgatgatcag agagcgggtt atgggtgata
      481 gccggagcga tgaaatcgca cggtaccatt ttggttccct ggtggatcag ctgatagaac
      541 gcgtgctgac cgttcgtacc tggttcaccc cagataatcg ggccagtctg gtaatccaca
      601 accttaccgt tacggtcaac atacttaccg ttggactcca tattgccctg ctggaagtac
      661 gccgcgaaac ggtgcatata ctggtcataa ggcagaatcg cttcagtttc cgcgccaaag
      721 aaattgttgt accagatgcc aatcagcgcc agcagtacag gcaggttttt ctcggcaggc
      781 gtggtggaga aatgcttgtc catcgcgtgt gcgccagaaa gcagttcaac gaagttatca
      841 aagccgatgg agagaacaat cgacaggcca atcgctgacc acaaagagta acgaccgccg
      901 acccagtccc agaattcgaa catgttggca gtatcaatac caaactcgcc aacggctttg
      961 gcgttggtgg aaagcgccgc aaagtgtttc gcaacgtgtt tctcatcact tgccgctttc
     1021 aggaaccagt cacgcgcgct atgggcgttg gtcatggttt cctgagtggt gaaggtttta
     1081 gatgctacca ggaacagcgt ggtttccggg tttacttttt tcagcacttc cgcgatgtga
     1141 gtcccatcga cgttagaaac aaagtgcatg ttcaggtggt ttttgtatgg acgcagtgct
     1201 tcagtcacca tgtacgggcc gaggtcagaa ccgccgatcc cgatgttcac tacgtcagtg
     1261 attgctttgc cggtatagcc tttccactca ccggaaataa tcgcttccga gaaggttttc
     1321 atcttctcca gcaccgcgtt gacttccggc ataacatctt tgccatcaac cagaatcggg
     1381 gtattgctac ggttacgcag cgctacgtgc agcacggcgc ggttttcagt gcggttgatc
     1441 ttctcgccag agaacatcga cttaatcgcg cccgccagat cgcactcttt cgccagatct
     1501 tgtaatttcg ccagcgtctc ttcagtgatg cggtttttgg agtaatccac cagcatctga
     1561 tcgtcgaagg ttgcggagaa cttagaaaaa cgatcgccgt ctttagcaaa aagatcggcg
     1621 atcgtaacgt ctttcatttc atcgaagtgt ttctgtagtg cctgccaggc agcggtctgc
     1681 gttggattga tgtttttcat tagcaatact cttctgattt tgagaattgt gactttggaa
     1741 gattgtagcg ccagtcacag aaaaatgtga tggttttagt gccgttagcg taatgttgag
     1801 tgtaaaccct tagcgcagcg aagcatttat tagctgaact actgaccgcc aggagtggat
     1861 gaaaaatccg catgacccca tcgttgacaa ccgccccgct caccctttat ttataaatgt
     1921 actacctgcg ctagcgcagg ccagaagagg cgcgttgccc aagtaacggt gttggaggag
     1981 ccagtcctgt gataacacct gagggggtgc atcgccgagg tgattgaacg gctggccacg
     2041 ttcatcatcg gctacagggg ctgaatcccc tgggttgtca ccagaagcgt tcgcagtcgg
     2101 gcgtttcgca agtggtggag cacttctggg tgaaaatagt agcgaagtat cgctctgcgc
     2161 ccacccgtct tccgctcttc ccttgtgcca aggctgaaaa tggatcccct gacacgaggt
     2221 agttatgtct gaaattgttg tctccaaatt tggcggtacc agcgtagctg attttgacgc
     2281 catgaaccgc agcgctgata ttgtgctttc tgatgccaac gtgcgtttag ttgtcctctc
     2341 ggcttctgct ggtatcacta atctgctggt cgctttagct gaaggactgg aacctggcga
     2401 gcgattcgaa aaactcgacg caatccgcaa tatccagttt gccattctgg aacgtctgcg
     2461 ttacccgaac gttatccgtg aagagattga acgtctgctg gagaacatta ctgttctggc
     2521 agaagcggcg gcgctggcaa cgtctccggc gctgacagat gaactggtca gccacggcga
     2581 gctgatgtcg accctgctgt ttgtcgaaat cctgcgcgaa cgcgatgttc aggcacagtg
     2641 gtttgatgta cgtaaagtga tgcgtaccaa cgaccgattt ggtcgtgcag agccagatgt
     2701 agccgcgctg gcggaactgg ccgcgctgca gctgctccca cgcctcaatg aaggcttagt
     2761 gatcacccag ggatttatcg gtagcgaaaa taaaggtcgt acaacgacgc ttggccgtgg
     2821 aggcagcgat tatacggcag ccttgctggc ggaggcttta cacgcaactc gtgttgatat
     2881 ctggaccgac gtccctggca tctacaccac cgatccacgc gtggtttccg cagcaaaacg
     2941 cattgatgaa atcgcgtttg ccgaagcggc agagatggca acttttggtg caaaagtact
     3001 gcatccggca acgttgctac ccgcagtacg cagcgatatc ccggtctttg tcggctccag
     3061 caaagaccca cgcgcaggtg gtacgctggt gtgcaataaa actgaaaatc cgccgctgtt
     3121 ccgcgcgctg gcgcttcgtc gcaatcagac tctgctcact ttgcacagcc tgaatatgct
     3181 gcattctcgc ggtttcctcg cggaagtttt cggcatcctc gcgcggcata atatttcggt
     3241 agacttaatc accacgtcag aagtgagcgt ggcattaacc cttgatacca ccggttcaac
     3301 ctccactggc gatacgttgc tgacgcaatc tctgctgatg gagctgtctg cactatgccg
     3361 ggtagaagtg gaggaaggtc tggcgctggt cgcgttgatt ggcaatgacc tgtcaaaagc
     3421 ctgcggcgtt ggcaaagagg tattcggcgt actggaaccg ttcaacattc gcatgatttg
     3481 ttacggcgca tccagccata acctgtgctt cctggtgccc ggcgaagatg ccgagcaggt
     3541 ggtgcagaag ctgcatttta atttatttga gtaaacgatc agtagaggtg aatagcgacc
     3601 cacgacgcta ttcaccatgc cggttcaatt acgaattact gcggcgctgt tgcttttccg
     3661 catgtacgcg tttcacaatc ttataaatcc attgcagcgt cagattatat ttcttcgcta
     3721 attcggcgta gttgcgccca tcgcactcgc tatagatttg gtagtcacgc tccgatgctc
     3781 gtccggagat ccccttaggg aaatagatgc tttgtccgcc ccagttacgc atcattcggt
     3841 cggcaatggc aaaacccaca ttttctgccg atgaactgtc gagattgatg ctttcaatca
     3901 gaacttgcga tgcatgaaaa gccaggtcgt taatgatctc cggtgtccgg gccatctctt
     3961 ttgattttcg tatcattttt catctccata tatcttgcat cctgaataag acccgatgcg
     4021 tgtaaaacca cggatatacg ctaagcagtt gtcattactg ctactcaata cattcaataa
     4081 acaaataaac aatcaccaaa aatataaact tttaatatta atgaacgtca taaattcacg
     4141 aaataaatat attgtttgga ttatgtttct tatcaacagg agtatcattt tacactatac
     4201 tgtatacata tacagtatta tttttacctg tagagtaaaa agatcgtttc cctcacagtc
     4261 gctgactttc ttaaacaaac tttaaaaatc aaataactat cgactattcc tacgatccac
     4321 catcatcttt cccctgcata atgacgcgct tattagcctg gtcacctttt gctctttaat
     4381 tgctgagtcg atttattagc gggcttgttc atttatagag aatctatttt ttaaacttat
     4441 ttattaaagc ttttttcatt cttcactggc gggttctgac gacactaaac gctcacttat
     4501 caggagatat cgtatgaaaa aagtcacttt tccccggctt tccggctggc tagtcgcttc
     4561 cgccgcgctg tttgtcgtga tcggctggac ctcttccgca cagatcccgg tcgtcattta
     4621 taaactaagc ctggtttcgc tttccgcggt gctgggatac tggctcgatc gcagtttgtt
     4681 cccctgggca cggcctgact cttttagccc ctggaaggaa cctcgttgct gcgcggcggc
     4741 aatgattcgc cgcgccatca tcgttgccgc cgtctgtctt tccgtcgcct tagggctata
     4801 gtgatgtggc tgaaatatat cgcgtctatg attattttcg ttcttttccc gcttaacgcc
     4861 tctgaaccgc cgcgagcctc tctggcatgg cgaaacgaac taattcgtac agctcgagaa
     4921 gtctgggggc tgaatgctcc agtggccgac tttgccgggc aattacacca ggagtccgcc
     4981 tggcagccaa tggtacgttc ccccgttggc gcacaaggta tggcgcaatt tatgcctgct
     5041 acagcgacat ggataagcca gttgtatcca caattgcgtg aaaacaaacc gtataaccca
     5101 acctgggcga ttcgcgcgct ggtgcaatat gaccagcatt tgtggaaaaa catctctgcg
     5161 aaaaatgatt gtcagcgtat ggcgtttacc ctaagcgcct ataacggcgg tcaggggtgg
     5221 gttaaccggg ataaaaaact ggctgcatcc aaagggttag atgccactag ctggtttggt
     5281 catgttgagc aagtcaacgc cgggcgcagc gccacgaact ggcgagaaaa tcgtcgctat
     5341 ccaaagatga tcctctatca acatgccgcc cgctatttac tctggggaca ggcaagctgt
     5401 cttcattaat cagaggggcc gatgaaactc agtatcgatt tttgggaagt gatctccctt
     5461 atgctttcct tcgttggatt aatgtttgct gccggaaaac tgctgttagc acaaattgaa
     5521 aaacgactta atgagcgttt tgagtctctg gaaaatgccc gcagggaatc agaaacaagt
     5581 tggtcgaaac tggaaagaga atttctcgaa tttcgtgccg agcttccgct gcattatgtc
     5641 cgcagagaag attatcttcg tgggcaagca gtattagaag cgaagctgga tgccttatat
     5701 agcaaaatcg agctgttaca acgtggcagt tattgaaaaa tccccaccct tatgtaaggg
     5761 tggggatttt tttaaccatt caattttttc tctaaatcac attaaaagat tcttcacctt
     5821 cgctgcttca gaatacattt caacgataac gaagtgagcg gtaattaagg tacagcctat
     5881 atggaaattt tatctgtaat gaattctgtt gtgaccagat tacgtgaaca caactccgaa
     5941 atggatatat ttatttcatc taaggatgcc cagaaatata ttccacagac acaacgagtt
     6001 gcagtgatta ttaattatag cggttctgtc tttgctacgc ccgaaagcag taatgccatc
     6061 gtgcaacagc aaatactccg cttaaccgcc accgttattg ttggcaaaaa ttgtgatgca
     6121 ttaaacgcac ttgatcacat acgcagcgca ttgggtggcc ttccgcttcc tgattgtgat
     6181 cgtctgcttt ggcttgaaaa agaaattaat acgggtgaga gcggcggttt ctgccgctac
     6241 atcctggaaa tggcgaccag ctcgctgttt atcgctgaac aggaaagcac ggatcttccc
     6301 ctgcttacgg aagttaacta cgaggaaact gaatgaaata catctacaac ggcccagcaa
     6361 gcggcgtcac ccttgccgat ggacaagaaa tcttattgtg gccgaacagt gaaattgatc
     6421 tgccagaaga caacgagtgg gtcatgacca tgattgcccg caatcatctg actcctgtca
     6481 tcactcagga agaacaaaat aacgtagagg aaattgtaca tggcagctaa ttatctgcac
     6541 ggtgtagaaa ctattgaaat tgaaaccggc ccgcgtccgg ttaaagcggt aaaatccgcc
     6601 gtcatcgctt taatcggtac atccccctgc ggtccggtaa ataaaccaac attatgcctt
     6661 tctgaaagcg atgctgcgca gtttggctcg actcaggcta actttacgat cccacaggca
     6721 ctgaaggcaa tttatgacca cggtgccggt acggtggtgg tgattaacgt gctggatccg
     6781 gcaaaacatg gctccaacat cagcaatgag agtatcactt ttgatgctaa caaccaggcg
     6841 aagctcgctc accgcaatgt gcgtaacgtg gtactaaagc cctcttcatc aaattcatca
     6901 acctttaaca ccgcagcatt tagcgtagat gaacaaacag gcataattac ccgtaaagga
     6961 gccgacattc ctcctggtgc gaaagtttgt gcctattatt cctggtgcga ccctacaaag
     7021 gtcaccgcag ccgatattat cggtaccgta aataccgcag gcgaccgcac ggggatgaaa
     7081 ctccttcagg acacctataa cctgtacggt ttctacgcca aaatcctgct tgctcctgtg
     7141 ttttgtacgc aaaaatcggt gactactgag ctgattgcac aagcggaaaa actcggtgcg
     7201 attacctaca ttgatgcccc gattgggaca acattccagc aggtattggc tggacgcggt
     7261 tcgcaagggg ctatcaactt caataccagc tctgatcgtg cgcgtttatg ttacccacat
     7321 gtcaaagttt acgatggcat cactaaccag gaaattcttg agcctctctc ttcgcgtgct
     7381 gccgggctac gtgccaaagt agacctcgaa aaaggtttct ggtggagcaa ctcaaaccag
     7441 gaaattcagg gtattaccgg tattgaacgt tcgctttccg caatgattga tgatccacaa
     7501 agcgaagtga atcagctcaa cgaaaacggc attaccacta ttttcaatag ttacggctct
     7561 ggtctgcgct tgtggggtaa ccgcacagcg gcatggccta ccgtgaccca tatgcgtaac
     7621 tttgaaaacg tccgccggac aggcgatgta atcaatgagt caatccgtta tttcagtcag
     7681 cagtatattg atatgccgat taatcaggca cttattgacg cgctgaccga atcggtaaat
     7741 acctggggcc gaaaactgat tgccgacggc gcactgcttg gctttgagtg ctggtacgat
     7801 ccggcacgaa attcaccggc tgaactcagc gccgggcatt tattgctgag ctataaattc
     7861 accccgccac cgccgctgga acgtctgacg tttgaaactg aaattacttc tgaatattta
     7921 gtctctctgg agagcaatag ctaatggctg gaaaaattca aattaaccgt attaccaacg
     7981 ccaatattta tctcgatggt aataaccttt taggccgtgc aacagaaatt aaattgccgg
     8041 atgtaagttt aattatgcag gagcataaag cactgggcat ggtgggtaaa atcgaactcc
     8101 cggcaggttt cgataaactg gagggcgaaa ttaaatggaa ctccttctat caggacgtaa
     8161 tgcgtaaaac ggcaaacccg tggcaggcgg ttgcattaca gtgccgctcc agtattgatt
     8221 gctataactc ccaggggaaa gcgaatcaat tagcgctagt gacacattta accgtgatgt
     8281 ttaaaaagaa tccactgggc acatttaaac agaatgaaaa cccggaattc agcagcgcct
     8341 ttggttgcac ttatattaaa caagtagttg atggtgaaac gctgcttgaa cttgattata
     8401 tggccaatat tttccgggtt aatggtgtgg atcaattaag tacctatcgc aataacatcg
     8461 gtggctaagt tattcggggc tacggccccg aactttgcaa aataaataag gacacaaaat
     8521 gaaagaacat tatatcttgc agtttccatt tacgtcggca gcaggaaata atatcgacac
     8581 gctgcaatta cgtcgcctga aagtaaaaga tatgcgcaac gcccgccgga tcagcgaaaa
     8641 gccagaagag tgggatgaac cgctgatggc ggcgatgacc ggactggtgc cagaagattt
     8701 agccgaaatg gatttgctgg attaccaggc attgcagaaa cgatttcaat ccatgcttac
     8761 cgtggttaca gaatcctccc ctgctatggc aggcaatggc gctactggcg agatggtttc
     8821 gctttccgcc cagtgagata gacgccctta ccgtcgatga ctttagcaac tggctggatg
     8881 aagccagcgc ccaaataaaa atcgaatatg actcgcagac ctgatgtctg cgagtttccc
     8941 aagcccgtca ggtttatttc ttccctgccc ctttttttag aaaaataacc agcgggccat
     9001 tatcaatatt taaagagaaa caattttggc caacgatatt attacccagc ttcaggcgcg
     9061 taatgagacg ttgacgcagg caatagcccg ttacggctca ctcaacgcca gaacattgtt
     9121 aactctctct actcagcagg cgacagttat caaactaacg cagcagcttg ccgattccgc
     9181 tctccgcctg gaggaaaata gccgcagccg cgctaatctg atggagaaaa cccaaacatt
     9241 tgccgggcaa tttagcaaag tattcaatgt tgaagccccc gactggaagt tgccgtatga
     9301 gtttcaggac aacatggtca atatggcgac caaaggtggg atgaatgcta caacccgcga
     9361 gacgctcagc cttaatctgc gcgactggag catggatttt aaccagcagc agaccacctt
     9421 acagaacgca gcccaaacgc tgatcgaagg caatttgtcg tcgatgcagg atctcaaccg
     9481 ttatatgccg gagatcgcca aagctgccac cgccacgcgc gaaagtgctg aaacgtgggc
     9541 gaatgccgcg ctcgcgactc atgatcgact gaatattgcc ccggaaaatt tccacgccgc
     9601 gcaaaacatg atgtacggca ttagcaaaag cggtgggcct gccattgctg aacaaacgca
     9661 gtggatagag aaatttgcag gtaaaaccgg cgctcagggt ctggaaggta tggctgaact
     9721 gactgccgcc atgcagatcg caatgaaaaa tggggccagc gccagtgcgg cggcggagaa
     9781 ttttgaccac tttctgcaaa ccaccttttc gaaaaaaacc gatagctggt tcgccagcca
     9841 gggcgtcgat ctgcaaggct ctctgcttga acatcagcaa aacggtatgg gtgttagcga
     9901 agccatgact catatcgtac aaatgcagct tgagaagatg aacccggcga tcctcgacac
     9961 cttcaaacgt actatgcaga ttgaagattt atctgctcgc agcaatgcgc tgcaatcgat
    10021 ggtgtcgcaa tttaatctgg gcgaaatgtt cggcgatgtg caaacggtgg aattcctggc
    10081 acctatgctg gcgaatatgg aggaatatcg ccagttaaaa gcctctgcca tgcaagccac
    10141 cagcaagaat ctgattaacg ctgacttttc tgcgcaaatg gcctcgccca ttgaacagac
    10201 taaagcgtta cagctggcat taaatgattt atggctcagc attggtttgc agcttatgcc
    10261 ggcgattggc gagctggcac aaagccttac gacggttatt cgccagttca gcgcctggct
    10321 acgcgaacat ccggcgctgg tgcaaaacat tgcgaaaatc gtcggggcgg tttggctgtt
    10381 taacggcgcg ctgaatgttt taaagctggg cgcgaacctc atcacctcgc cgtttattcg
    10441 tctggtcgat atcttcctga aagtcaaggc aagtctggcg ctcacaggcg gggcaagtaa
    10501 gatgctatca gcggttaagt cattgggtgg cggcgcaaaa tggctaatgc aactgcttgg
    10561 tcgtggcctg attggcgcac tgaaacaggt aggtcagacc gtcttctggt tgggtagggt
    10621 tttattgatg aatcccattg gtctggtcat cactgcgatt gcgggcgctg cttatctgat
    10681 ttgtcgcaac tgggagccta tctccaggtt cttttcgacc atctggcaac gtatcaccac
    10741 ggcctttgac ggcggcattg caggaatttg tcggttgatt ctcgactggt caccgctgga
    10801 gttgttctat agcgcctttt ccagtgtgat gaattggttt ggtgtcgaga tgcctgcaag
    10861 ttttagcgag ttcggcagca atcttctggg cagtctggtt gacggcataa tgaatgcctt
    10921 ccccgctctg aaaggcatta ttgatcaggt aaaaaacgcc atcccagact ggctaaaaac
    10981 cacgatgggt attagtacag aaggatcggc tacagctatt acaagcacga ctaataccgc
    11041 atccgtctcc cccgcgaccg ttgttccagg cgttgccggt gcgattttaa caccgccggt
    11101 gggcaaacaa ctcgcgccat ccggcaaaac ggctacgccg tcatcggcgc cagcggcaaa
    11161 aaatacagcc gccaaacccg tatctgcctc tttacctggt aaatccgtaa ccaaaccggc
    11221 gacgctaccc tcccgttcct caggaaaagt ccaggtaaat ttttcgccac aaattaccgt
    11281 gcagggtaac ggacaaaaca ccactaaaga gattcagaac gtgttgacga tgagtaaacg
    11341 cgaactggaa agaatgatta acgatgtaat ggcgcagcag cagcgccggg ggtatgcctg
    11401 atgtatgccg ttttaggaga gattgaattt aaggttgtca cattctggga cggctttaaa
    11461 agcacaatgg gcgtggatta cgccacacat gcccgtatag aaggcaaacc cggcgtgcag
    11521 tttattggcg ataagctgga tatgctggcg ctggaatttt ccctgcacag ccagttttgc
    11581 cagcccacaa cagagctgaa ccgactgcgt gaagccatgc ttgctcacaa ggcgatggca
    11641 ctggtatttg gcaatggcga ttatcgcggc tggtttgtga ttacggagct aaccgccacc
    11701 caccagcaca ccgatccctg gggcaatgtg attgcccaaa acggaacgat gtcgctccag
    11761 gagtacaccg gcgatcctaa aaatccactt ttacctccgg cgattaccac ccaggagccc
    11821 aacatcgagg aaaaggcgag cgattttccc gacaaggtgg agtcctggtt tgatcagata
    11881 ttaaacgcca tcgaagaagg tatgcgtaag gccaaagaga tgctggatga actgacacaa
    11941 gccattgaag atattaaaaa aacggtggca aaagtgaaag caatgattaa agaggccaaa
    12001 gcgttaaaag aaaagtgtga aaagataatt acgtcattga aaaagacaat cgacgccatc
    12061 gaaaccctgt ttaaacagcc aatggatctg caaacgctgg caggactccc aaaagcgttg
    12121 tcggcgcaga ttaaaacttt actgggtaac atgccaggta tccgggactg cgccaatgac
    12181 gccagtacac tggttgacca tgctcaggcg cttttcgacg acattaccag cgacatcgcc
    12241 gaagcgacgt ttgataaagc cgcaacgttg gttgatcagg cacgaacaac ggtacaacaa
    12301 accactccca cagtgagcca gcttgctgcc gcgaccatta cgaggatctg gtgatgcgat
    12361 accttgaaca tatcaccacc gacggcgaac gctgggataa tctggcatgg cattactacg
    12421 gtgatgcgct ggcttatgaa cgcataatcg ccgccaatcc acatgtagcc atttacccgg
    12481 tactgccttc cggtattcag ctcattattc cggtcatttc cgtcaataaa accttatcgg
    12541 agatcccacc atggctgaga taagcgtaac tggtggcgtc tttgccacac tcacgcccat
    12601 ttttaccctc tggtatgggc ataaagatat cacttatgac atcacaccct atgtcaccag
    12661 catcagttac cacgacagca tcaaaaacga gtcggatacc atcgcaatta cactggatga
    12721 cacagatgga cgctggataa aagagtggta tcccggcaaa ggcgatacgc tggcgctgca
    12781 tatgggttat cagggagaga agctgctcga ttgtggtcag tatattattg ataaaattga
    12841 tatttcagcg ccaccttcta cggtaaatat tgatggcatc gccacttccg tcaatcaggc
    12901 gctgcgcacc cgtaacagcc agggttttga agaaacgacg ctttcggcta tcgccagccg
    12961 tatcgcacaa actcacggcc taaagctggt gggcaaaatc gagcctctga caattgaccg
    13021 ggtgacacag tacggcgaaa ccgatgttgg atttctcaaa cgtctggcca gtgaatatgg
    13081 ttatgccgta aaagtgacga cgaaagagct gattttttca catttaccca cgctgcgctg
    13141 cctggcacct gtgaaaaaga tcgaccgcaa agacgtttcg catttcacct tcaaagatac
    13201 cattaaccgt atctacaaaa acgccaccgt acagcatcaa aatagtaaga aaaaagaact
    13261 ggttatctac actcacaaca gccagcaaaa accgtctgcc cgtggagtcg gcaccagtgc
    13321 cgacacgcta aaactgaaca gtcgggcgac ggacgttggc gcagcacagg caaaagccaa
    13381 cgctgcactc gacagccaca acgaatatca gcaaaccgga acgctcacaa tgatgggctg
    13441 cccggaactg acggcgggca ataaaatcga gctaaccgat tttggcgtgc tttccggtca
    13501 atggctaatt gataaatcga ctcacagttt tgtgcgcagc ggctatacca ctgaaatcga
    13561 cgtgtcgcgc gggccagcga ccagccagta aggaggaaat atgaaaggag taacccgtca
    13621 aacggggatt atcagcgata ttgacgaaac cagcgttcgg gtgcgggtca cgctcccgga
    13681 gtgtgacaat ctgaagagca actggcttgc ggtacttcaa cgcaattccc aggacaataa
    13741 agactactgg ctaccggata tgggcgagca agtggaagtt ctgctggaca ataacggtga
    13801 agatggcgtg gtgctgggcg cagtttattc tacggttgac accgcgcctg tagcctcgcg
    13861 cgacaaacgt tacgtccagt tttctgatgg cgcagcgttt gaatatgacc gcagcacgca
    13921 ccagctgacg atcaacggcg gtatcgagaa aatcgtgatt gaggttatca acggtacctg
    13981 cctgacatcg cccaacgttg agattaaagc ccaacaggtc accgtgactt ccgataccgt
    14041 cgatgttaaa gcgaccgatg tcagcatcga cgccactaag gtcgaggtta aagcagcagc
    14101 agtgacggta gatgcgccca tgagcacctt tactggcaac gtcacggtaa tgaaaaaact
    14161 cacctggctt ggcgggatgg caggaagtgg aggcatcggt aacgcagcca cgataaccgg
    14221 caatgtcaac gtgatcggca acgttcaggc cagcggcgca ttgcaggaca gcggtggcaa
    14281 ctccaaccac cattcacact gacgtttaac ccgcctgatg gcgggttttc tctttttaat
    14341 caatcagttt tctaaatcgc tttaatatct ccacagcccg ttcagggcga aaataccctc
    14401 atgaacacaa aaacacgccc ctcaacgctg cactggcaac cggccttgct gcggcctgaa
    14461 gaatacgtct gcggactgga tgatattcac caggcaatac acatcattct gcgtacaccg
    14521 cgcggcagtg atccccacag accgctgttt ggcagcaact tgtggcacta catcgattac
    14581 cccatcgagc gggctatccc gcatgtggta cgggagtcgg tggaagccat ccgccagtgg
    14641 gaaccgcgct gtcggttgct gaaggtgaca ccagtaatcg acggcgaaca tctgacgtta
    14701 cgtgtgcaat ggcgcgccgc tgacggcgtt atcaactcaa cggaggtgtt atggcgatag
    14761 ccgaacccaa ttttattgac cgcgatcctg cgcaaattac cagtgagatg attgcgcaat
    14821 acgaagatgc cagtggtaaa aaactctatc cggcacaggc tgagcggttg ctcatcgacc
    14881 tgtttgccta tcgtgaaaac cttgtacgca tcgccattca ggaagcggcg aaacaaaacc
    14941 tggtcgcgta ttcccgcgcg ccaatgctgg attatttagg agagctggtg ggcgttcacc
    15001 gtttgcctgc gcagccagca aaaacgacgt tgcagttttc ggtcgtcagt gcgtatacca
    15061 gcaatatcct gattccccag gggacgcggg ccagtgcctc tgatagcgtg atgttcgcca
    15121 ccgatgaaga tgttctgctt ccggcctgga gtttgcatat cgccgttcct gccaccagcc
    15181 tcgcagcagg tgaacagggt aacggctggc agcctgcaca aattagcgct ctggtcgaca
    15241 ggattggtca ttatgacatc aacgtaacca acctgactgc gtcaacgggc ggctgcggtg
    15301 aagagagcga tgacgcattg cgccagcgta tccaactggc accagaaagc tttagtaatg
    15361 cgggcagcta tggcgcatac cgctttcata cgctttctgt tagccagtcg attattgacg
    15421 ttgcagtact ggggccggac gagggattgc cagaaggctg cgtggagatc tacccgctaa
    15481 ccctgaatgg actgccagga atagaactgc tcgcgcaaat cgaacaggag gttagcaagg
    15541 agaaaaaacg tccgctgacc gacaaagtga gtgcgaaatg cgctcttcga gtgccgtatg
    15601 agatccgtgc gcagctaacg ctgtttacca ccgccgatca ggagacaacg ctggctgcgg
    15661 cgcgtaaagc gattagcctc tggacgcaac agcggcagaa acatctgggg caagacattg
    15721 tgccaaacca gataatcaaa gtgttacagg tcgatggcgt ctatgacgtt gcgctgaact
    15781 tgcctacaaa acgtattttg caggcgcatg aatgggcgga atgcactgca atagacgtca
    15841 cgatcgccgg agttagcgat ggataaattg ctaccaccgc cgccgcttgc cagcgatgag
    15901 cgtttttcga ttctggcaaa tatcgccgcc gagcgttttg cccaactcga tctgacggcg
    15961 ttgatggttt atctggtcga cctggttgat gcttcggcat taccagccct tgcagaacaa
    16021 tttcacgttc aggggttgga aggttggtta tttaccaccg atgagcggga gaaacgcgag
    16081 ttaattaaac aagccattga actgcataaa tataaaggaa caatttgggc ggtgcggcgg
    16141 gtgctggaaa tactctcctt acccggaact atttcagaat ggtttgaata tgggggaagg
    16201 gcttactttt ttaaggttga tattacacta gaggaaaaag gattaaatga agatgaattc
    16261 aatgcactta tcacattaat tcatgaatat aaaaatgtcc gttcaaagct ggaaagcatt
    16321 gttatttggc ttattaatcg aagcccaata ccagttattg gcagtgccat gcaaggaggg
    16381 gaagtcatta cagtattgcc tcctgttgca gaaagcctca gccagtcatc tggaatattt
    16441 ttagcgacag gttattgtgt ggaggaatat attcaactac taccttatca acccgatcga
    16501 ctaacacaat cccaaccgat gaaggtcggc acaggatact ggagcaccga aattatgtct
    16561 gtatatccgg agtaataatg gcaagtgaat tttttacaat attaactgct gcaggcaaag
    16621 ccaaaattgc ctcagcactg gccgagcaaa aacagatccg tctgcaaact atggtagttg
    16681 gcgacggtaa tggtaaatat atcgaaccga cagaaagtca gaccaaagta gtccatgagg
    16741 tctggcgtgg tcagctcaat acattaaaaa ttgcgccaga taatccggcc tgggttatcg
    16801 cagaagcgat tattcccgaa caagtcggag gctggtatgt acgcgaagtt gggttactgg
    16861 ataccgacgg cacgatggtc gctattggta aattcccgga aacctataag ccacgattac
    16921 ctgcgggggc cagtaagcaa atcgttatac gcgcggtcat ggaagtcacc aatgcagatg
    16981 cggtgacgct tttgatcgac ccttcagtcg ttgtggcaac cagggaatat gtcgatgacg
    17041 cgttgaaaac acatcagcaa tcacgaaatc atcctgatgc gacgctgaca caaaaaggtt
    17101 ttacgcagct gagtaatgcg actaatagcg atgatgaaac caaagcggcc acgccaaaag
    17161 cggtaaaaac ggcatatgac ctggcaaata gcaaagctgc caccagtcat aatcatgcct
    17221 ggaatcagat tactggtatc cctgatggta cactgacgca gaaaggagtc gttaagctta
    17281 acaatacaac aaatagcacc agtacgacgg aagctgcaac accaagtgcg gttaaggcag
    17341 cgatggataa ggctattgct gcggcaccgt ccagccatac ccatgcctgg gggcaaataa
    17401 caggtatccc cgacggtacg ctgacgcaaa aaggggtcgt gaaacttaat aatgcgacca
    17461 acagcaccag tacgacggaa gctgcaacgc cgaacgctgt taaggcagcg atggataagg
    17521 ctattgctgc ggaaagctgt cctgttggga tgcctattcc ctggccatct gattctgtac
    17581 cttcaggcta cgctctgatg acaggtcaga catttaataa aacctcctat cccaaactgg
    17641 caattgcata tccatctggt gttattcctg atatgcgcgg atggataatt aaaggaaaac
    17701 catccagtgg gcgcgctata ttatctactg aactggatgg agttaaatca cataaccata
    17761 cgggcagtat ttcgagtacg gacttaggga cgaaatctgt atcatcaata gatctaggaa
    17821 caaagaacac tcagtcattt aatcatggga taaaaacaac aaatacagca ggcgcgcata
    17881 gccatgatag tggttctggc gaaagtagtg aggggggaaa acctcggtat ggtactcgtg
    17941 ataacacaac aaataatttt ggttctggtg aatcagatca tgacaattac aaatttaaca
    18001 catccacgga tggagagcat gcacattcag ttaatgttgg ctcacactct cactctgtta
    18061 ttttagggtc acataatcat tcaattgccc ttggttccca taatcactcc ctaaccatta
    18121 ataataccgg caacaccgaa aacaccgtca aaaatatcgc attcaactat attgtgaggc
    18181 tagcatgaat acttttacct tttccgatga agctcaaata ctaactgtat ataatttttc
    18241 acaagactcc caagaatata tcggtgagtc tgatgcatac attgcaccta atacaggctt
    18301 gccaaattat tgcacattaa tttcacctcc cgaaaaggtt cctggtttta ctccagtgtg
    18361 ggagaatgaa acatggagac ttattgaaga tcatcgaggc caaactgttt ataacaaagt
    18421 tgatggtagc cagcttatta ttcaagaatt gggccaatta cctgaaaatg taacagtcat
    18481 ttccccgaca ggttcttttg aacgttggga tggtgaaaaa tggcaaccat ctataaccga
    18541 tgctaaagag gcgaaatact ctgcaatcaa aaatcaacgc gatgccatca caaccgatta
    18601 catcatcatc aacaaccatc acttccacag tgatacaaat agccgtatcc aacagctttc
    18661 actcacaaaa atgggagcgg agaaaaaaat tccgccaggt ttaatgtgga aaactaaaaa
    18721 taatggtctg attgagttaa ccaacgaaat cgctgcccag tttgaatcgg tcaccatgga
    18781 tcacgatatg cgcttgttcg caaacgccca gcgtcatatc gcggcggtgg aagcactgga
    18841 cgatattcag gcggtgctcg actacgatta ttcaacaggc tggcaaccat gagtaaaacc
    18901 actgtctggc tcgcttgtta taagggccga acagagcacc gtggtattgc ccgactggct
    18961 gactggctta cccgtaaaat cacacgcggt cattattccc actgtgaatt agccgttaag
    19021 catggtgaaa agagatacct ttgttactct gcatcactgc gcgatcgcgg tgtacgcgga
    19081 aagataatgc cattgccagc ggataagtgg gatatgctgc cgctccaggc tagccttcag
    19141 gatgtggaaa cttttttccg taaacatgat ggcaaaaaat atgactggcg cggagcatta
    19201 ggaattatta ccggtaataa agaacagcgc gatcgcctgt tttgcagtga attttgtgct
    19261 gaatttctgc aactgaagga aagctggcgc tattctccaa accacttgta cgctttagtc
    19321 agcagctggc aataccagca ataaatcacg ccgggcttta tgcccggcac attaccgttt
    19381 gatacagcaa attatctagc tcccgaacat ctccatctcg actgtccggt aaaatcggtg
    19441 gaatttcccc gcgcgccagt tccgcgcgaa taaacgcatg caataaagga cggcgcagtc
    19501 catattccgc ttcactcgca cgctgtttac gctccagcaa ttcatctatt tctgcgcgta
    19561 aggccgcatc caactcactt cccgccagta actcggcaaa gcgcattggc ggcacgcctt
    19621 ttcccgcttc aacccagcgt acggccagca gcgggcgcag cacgtaaaag tattttttca
    19681 gtcgaacttc gtcgccctgt aaataaccgc gaaagttttt ctgcgccatc gaatagtaat
    19741 gccaacgcgc gcgcaacgaa gaaaaccaca ttgggaccat tgccttaagc gccgttatcg
    19801 tttcttcatc ttgttgatag accaccggag aatccagcca ttctatcagc gtcggattcg
    19861 cgcctttcaa taatcccagc gccttacgcc actcccaacc ggaaacatct aactcgtcgt
    19921 cgataggcag ttcgataaca tcgcgcggtg actctacacg cagataccat tctagcggat
    19981 ggacatacaa aaaccgtaca tcgtagtcgc tatcgggcga ggcaaatccc cagccgcggc
    20041 tgcctgattc acaggcgtac agcactttca cgccatagcg acgttctatt tcttttaact
    20101 gctgcgatac ccgttcgcgc atcgcagcac tgactccatt taatggcatt tgactcatcc
    20161 tttgatattc actaacccgt gcagaacctg atccagacca ccaaatacag agatgttatc
    20221 gatccgctca gccactctct ccagcgtttc cagttctttt aagcgtaacg ccaccgggtt
    20281 gttttccatg actttagcgg tattgagtaa cgaacgcgtc gctgccgttt cttcacgccg
    20341 acgaatcaca ttcgcctgcg cagatttctc tgcctcaacc agctgcgcga ggatattttt
    20401 catatcacca ggcaggacga tatctttcac ccctaatgag gcaatctcca taccaaatgg
    20461 caacatgcgc gatttcacct gttcgctgac aacgtcatca atgacctgtt tatcttccag
    20521 caactcatcc agcgtacgcg tacctaccgc ttcacgcagt gcaaattgca attcccgata
    20581 caaatgatca atcggcttcg ttaactgact aaatgccaat aacacgtcgc tgtagcgcca
    20641 gttggcggcg aggttaatcc gcagattgac cttatctttc gttaagattt cttgcccgct
    20701 gacttccagt acctgcaagc gggtgtcaac cacttcagct tcaaccagat ggttaatttt
    20761 ccagtacgca gtcagtcccg gcggtaacag cgcctgcgtt ttaccatcga ttttcagtac
    20821 acctacgtgc caggccggaa cctgcaccgt cagtatcgca tcgcggcctt taactgcccc
    20881 tttgcgccgt ggctgcaata ccgcattcat cacctccgtt tgaacctgga cttgctgcgt
    20941 actcatccgc accagcgtca aatcatcctc tacacgccag tacaaacgac gcgttgatgg
    21001 cggcaggatc tccagcaaaa taccgtccat atacaacgcc ccggcttcag tctccgacaa
    21061 gtcggccacc acgcaatatc tttccaccca ctctggctga aagcggcgca aataatccgc
    21121 cagcacgtcg ggaacttcgc tgccatcgag cgtaatcagc aagacttctg gcgtatttaa
    21181 ccagggtaaa agatgctcgc ctgcatgcag cactttgtag taatcgccat ttctggaaag
    21241 taatgccagc tgatcttttc ttacgcttat tttcttaatc attatctatt ccttgcttaa
    21301 tagccgtcgc ggaagcagat acgaagcgac aggggaattc ccttttgcct gttacccggc
    21361 gtctttatcg gcgacgttat cggggatcgc tgactgcgca atccctcatt ttttatttaa
    21421 taagttacaa ccagtattca tttcaggaat gaattcggga atcgaacccg taattggcgt
    21481 caaaggctga cggaacacgc ccggaaaaca gcctggccgt tcctggtgtg ccgacggggt
    21541 ttaatcccct ttgaaattcg gtatcaacgc aaaagagtta ttgcgaaaag tgtgccaaaa
    21601 gtgaaataac acacttaata tattgaataa taaagattta attaaatcag ataacttgcc
    21661 ggataataat ttgcgttaaa tttttatctg tatttatcgc taattatcga aagagataaa
    21721 tagttaagag aaggcaaaat gaatattatc agttctgctc gcaaacgaat tcccgtacac
    21781 tgaactctct ggctcactga gggcaccatc atggcactcc cccgtattac ccaaaaagag
    21841 atgactgaac gcgagcagcg tgaacttaaa acactgctgg atcgggcgcg gattgcgcat
    21901 ggtcgcgtac tgaccaactc cgaaactaac agcattaaga aagagtacat cgataaatta
    21961 atggtcgagc gtgaggctga agcgaaaaaa gcccgccaat tgaagaaaaa gcaggcttat
    22021 aaaccggatc ctgaggcgtc atttagctgg tcagcaaata cgtcgacgcg cggcaggcgc
    22081 tgattaacgc cccttctttt tacgccccgg cgaggtaaaa cgcttaccgt tggacgccgg
    22141 gcgaccgcct ttttccaccg ttttttccat cttaacgact ggacgtttga tgcctaccgt
    22201 tttcggtttg gccttcgctt taggttttgc ctcggaagag gaattttcaa tgagcttaaa
    22261 gagatcgatt aactcatcgt cggttaaatc gcgccactca cccagcggaa tgccgcttaa
    22321 gctgacgttc ataatgcgcg tacgttccag ctttttcact tcgtaaccaa agtgctcgca
    22381 catgcgacga atctgacggt tcagcccctg caccagggta atgcggaaga caaacggtgc
    22441 ttcttttttg actttgcact ttttagttac cgtcccgagg atcggtactc ccgcccccat
    22501 accacgaata aattcatcgg taatcggttt atcaaccgtc accagatact ctttctcatg
    22561 atcgttaccc gcacggagga tcttattcac cagatcgccg tgattggtga ggaaaatcag
    22621 cccctgggaa tctttatcca ggcggccaat cgggaacacg cgtttgctgt ggttaacgaa
    22681 atcgacaatg ttatcgcgct cgccatcttc ggtggtgctg acaataccga cgggcttgtt
    22741 cagggcgata agtaccaaat cttcggcttc ccgaggctca atcaactgac cgtttacttt
    22801 cacaacgtcg ccgggtttca cctgatcgcc aatggtggct cgcttgccat taaggaacac
    22861 attgccttgc tcgatatagc gatccgcttc gcggcgtgag caaattccgc tttcgctgat
    22921 gtatttattt aaacggactg atgagtcggg cagcataaat tctcctgtaa aacgcggaat
    22981 ataccgtacc tcttagcggg gaaaaacagg gttatgcggc aacgtcgaaa ttaaatgtga
    23041 tctgccacgc cttttatcac aaaagtgtct ccggaaatac gatgcaaatt tgcctggcaa
    23101 aataaggata atcaacatat tacgaatcgc tgcacacctg tgctgatgac tactacgcag
    23161 agaaacaaat gtgcaagaga aagcgctatt tctccccatg caaagagtga aaaatcgctt
    23221 tgaaaggcca tcatgatggg gttatatcag atcaagcggt gagaaagcgt atttgcacaa
    23281 atgtgcagaa ccaggaggcg gcaatggaaa acagtgacga tatccgtttg attgtgaaga
    23341 ttgcccaact ctattacgaa caggatatga cgcaggcgca aatcgcgcgc gaactgggta
    23401 tttaccgcac caccatcagc cgcttgctta aacgaggccg cgatcaggga attgtcacca
    23461 tcgccatcaa ctatgactac aacgaaaatc tctggctgga gcagcaactg aagcaaaagt
    23521 ttggcctgaa agacgttgtg gtggtgtcgg gaaatgatga ggatgaagag actcaactgg
    23581 cgatgatggg gttacacggc gcgcaactgc tggatcgctt gctggaacct ggcgatattg
    23641 ttggtttttc ctggggccgc gcggtgagcg cactggttga aaacttgccg caggcggggc
    23701 aatcgcggca gttaatctgc gtaccaatta ttggcggacc gtccggtaaa ctcgaaagcc
    23761 gctatcatgt aaacacatta acctacagcg cggcagcgaa gttgaaaggg gaatcgcatc
    23821 tcgcggattt tccggctctg ctggataacc cattaattcg taatgggatc atgcagtctc
    23881 agcactttaa aaccatctct gcctactggg ataatctgga tgtcgccctg gtgggaattg
    23941 gctcaccggc cattcgcgac ggcgctaact ggcatgcgtt ttatggtggt gaagagagtg
    24001 acgacctgaa tgcccgccag gttgctggcg atatttgctc gcgctttttt gatattcacg
    24061 gcgcaatggt tgaaacgaat atgagcgaaa aaacactctc tatcgaaatg aataaattaa
    24121 agcaggcacg atattccatt ggcattgcca tgagtgaaga aaaatacagc ggaattgttg
    24181 gtgcactgcg tggaaaatat attaattgtc tggtaacgaa tagcagcaca gctgaactat
    24241 tac
//
LOCUS       DADXDL010000070        24150 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.070, whole genome shotgun sequence.
ACCESSION   DADXDL010000070 DADXDL010000000
VERSION     DADXDL010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 24150)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 24150)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..24150
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.070"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            204..1298
                     /gene="gcvT"
                     /locus_tag="IRB70_003322"
     CDS             204..1298
                     /gene="gcvT"
                     /locus_tag="IRB70_003322"
                     /EC_number="2.1.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system aminomethyltransferase
                     GcvT"
                     /protein_id="HBC0633198.1"
                     /translation="MAQQTPLYEQHTLCGARMVDFHGWMMPLHYGSQIDEHHAVRTDA
                     GMFDVSHMTIVDLRGSRTREFLRYLLANDVAKLTKSGKALYSGMLNASGGVIDDLIVY
                     YFTEDFFRLVVNSATREKDLSWITQHAEPFGIEITVRDDLSMIAVQGPNAQAKAATLF
                     NDAQRQAVEGMKPFFGVQAGDLFIATTGYTGEAGYEIALPNEKAADFWRALVEAGVKP
                     CGLGARDTLRLEAGMNLYSQEMDETISPLAANMGWTIAWEPADRDFIGREALEVQREH
                     GTEKLVGLVMTEKGVLRNELPVRFTDAQGNQHEGIITSGTFSPTLGYSIALARVPEGI
                     GETAIVQIRNREMPVKVTKPVFVRNGKAVA"
     gene            1322..1711
                     /gene="gcvH"
                     /locus_tag="IRB70_003323"
     CDS             1322..1711
                     /gene="gcvH"
                     /locus_tag="IRB70_003323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein GcvH"
                     /protein_id="HBC0633199.1"
                     /translation="MSNVPAELKYSKEHEWLRKEADGTYTVGITEHAQELLGDMVFVD
                     LPEVGATVSAGDDCAVAESVKAASDIYAPVSGEIVAVNDALSDSPELVNSEPYAGGWI
                     FKIKASDESELESLLDATAYEALLEDE"
     gene            1830..4703
                     /gene="gcvP"
                     /locus_tag="IRB70_003324"
     CDS             1830..4703
                     /gene="gcvP"
                     /locus_tag="IRB70_003324"
                     /EC_number="1.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminomethyl-transferring glycine dehydrogenase"
                     /protein_id="HBC0633200.1"
                     /translation="MTQTLSQLENSGAFIERHIGPDAAQQQEMLNAVGAQSLNALTGQ
                     IVPKDIQLATPPQVGAPATEYAALAELKAIASRNKRFTSYIGMGYTAVQLPPVILRNM
                     LENPGWYTAYTPYQPEVSQGRLEALLNFQQVTLDLTGLDMASASLLDEATAAAEAMAM
                     AKRVSKLKNANRFFVASDVHPQTLDVVRTRAETFGFEVIVDDAQKVLDHQDVFGVLLQ
                     QVGTTGEIHDYTALISELKSRKIVVSVAADIMALVLLTAPGKQGADIVFGSAQRFGVP
                     MGYGGPHAAFFAAKDEYKRSMPGRIIGVSKDAAGNTALRMAMQTREQHIRREKANSNI
                     CTSQVLLANIASLYAVYHGPVGLKRIANRIHRLTDILAAGLQQKGLKLRHAHYFDTLC
                     VEVADKAGVLARAEAAEINLRSDILNAVGITLDETTTRENVMQLFSVLLGDNHGLDID
                     TLDKDVAHDSRSIQPAMLRDVEILTHPVFNRYHSETEMMRYMHSLERKDLALNQAMIP
                     LGSCTMKLNAAAEMIPITWPEFAELHPFCPPEQAEGYQQMIAQLADWLVKLTGYDAVC
                     MQPNSGAQGEYAGLLAIRHYHESRNEGHRDICLIPASAHGTNPASAHMAGMQVVVVAC
                     DKNGNIDLTDLRAKAEQAGDNLSCIMVTYPSTHGVYEETIREVCEVVHQFGGQVYLDG
                     ANMNAQVGITSPGFIGADVSHLNLHKTFCIPHGGGGPGMGPIGVKAHLAPFVPGHSVV
                     QIEGMLTRQGAVSAAPFGSASILPISWMYIRMMGAEGLKKASQVAILNANYIASRLQD
                     AFPVLYTGRDGRVAHECILDIRPLKEETGISELDIAKRLIDYGFHAPTMSFPVAGTLM
                     VEPTESESKVELDRFIDAMLAIRAEIDQVKAGVWPLEDNPLVNAPHIQSELVAEWAHP
                     YSREVAVFPAGVADKYWPTVKRLDDVYGDRNLFCSCVPISEYQ"
     gene            complement(4867..6300)
                     /gene="bglA"
                     /locus_tag="IRB70_003325"
     CDS             complement(4867..6300)
                     /gene="bglA"
                     /locus_tag="IRB70_003325"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311800.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase BglA"
                     /protein_id="HBC0633201.1"
                     /translation="MKKLTLPKDFLWGGAVAAHQVEGGWNKGGKGPSICDVLTGGAHS
                     VPREITKEVLPGKYYPNHEAVDFYGHYKEDIKLFAEMGFKCFRTSIAWTRIFPKGDEA
                     QPNEEGLKFYDDMFDELLKYNIEPVITLSHFEMPLHLVQQYGSWTNRKVVDFFVRFAE
                     VVFERYKHKVKYWMTFNEINNQRNWRAPLFGYCCSGVVYTEHENPEETMYQVLHHQFV
                     ASALAVKAARRINPEMKVGCMLAMVPLYPYSCNPDDVMFAQESMRERYVFTDVQLRGY
                     YPSYVLNEWERRGFNIKMEDGDLDVLREGTCDYLGFSYYMTNAVKAEGGTGDAISGFE
                     GSVPNPYVKASDWGWQIDPVGLRYALCELYERYQKPLFIVENGFGAYDKVEEDGSIND
                     DYRIDYLRAHIEEMKKAVTYDGVDLMGYTPWGCIDCVSFTTGQYSKRYGFIYVNKHDD
                     GTGDMSRSRKKSFDWYKEVIASNGENL"
     gene            6345..6656
                     /locus_tag="IRB70_003326"
     CDS             6345..6656
                     /locus_tag="IRB70_003326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBC0633202.1"
                     /translation="MQPNDITFFQRFQDDILAGRKTITIRDESESHFKTGDVLRVGRF
                     EDDGYFCTIEVTATSTVTLDTLTEKHAEQENMTLTDLKKVITDIYPGQTQFYVIEFKC
                     L"
     gene            6820..7479
                     /locus_tag="IRB70_003327"
     CDS             6820..7479
                     /locus_tag="IRB70_003327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBC0633203.1"
                     /translation="MVQKPLIKQGYSLAEEIANSVSHGIGLVFGIVGLVLLLVQAVDL
                     NASATAITSYSLYGGSMILLFLASTLYHAIPHQRAKMWLKKFDHCAIYLLIAGTYTPF
                     LLVGLDSPLARGLMIVIWSLALLGILFKLTIAHRFKILSLVTYLAMGWLSLVVIYEMA
                     IKLAAGSVTLLAVGGVVYSLGVIFYVCKRIPYNHAIWHGFVLGGSVCHFLAIYLYIGQ
                     A"
     gene            complement(7556..8536)
                     /gene="ygfZ"
                     /locus_tag="IRB70_003328"
     CDS             complement(7556..8536)
                     /gene="ygfZ"
                     /locus_tag="IRB70_003328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-modifying protein YgfZ"
                     /protein_id="HBC0633204.1"
                     /translation="MAFTPFPPRQPTASARLPLTLITLDDWALATITGADSEKYMQGQ
                     VTADVSQMTENQHLLAAHCDAKGKMWSNLRLFRDGDGFAWIERRSVREPQLTELKKYA
                     VFSKVTIAPDDERVLLGVAGFQARAALANIFSELPSKEKQVVKEGATTLLWFEHPAER
                     FLIVTDEATANMLTDKLRGEAELNNSQQWLALNIEAGFPVIDAANSGQFIPQATNLQA
                     LGGISFKKGCYTGQEMVARAKFRGANKRALWLLTGSASRLPEAGEDLELKMGENWRRT
                     GTVLAAVKLEDGQVVVQVVMNNDMEPDSIFRVRDDANTLHIEPLPYSLEE"
     gene            8789..9055
                     /gene="sdhE"
                     /locus_tag="IRB70_003329"
     CDS             8789..9055
                     /gene="sdhE"
                     /locus_tag="IRB70_003329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000354044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD assembly factor SdhE"
                     /protein_id="HBC0633205.1"
                     /translation="MDINNKARIHWACRRGMRELDISIMPFFEHEYDSLSDDEKRIFI
                     RLLECDDPDLFNWLMNHGKPADAELEMMVRLIQTRNRERGPVAI"
     gene            9036..9443
                     /locus_tag="IRB70_003330"
     CDS             9036..9443
                     /locus_tag="IRB70_003330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YgfX"
                     /protein_id="HBC0633206.1"
                     /translation="MVLWQSDLRVSWRAQWLSLLIHGLVAAVILLMPWPLSYTPLWMV
                     LLSLVVFDCVRSQRRINARQGEIRLLMDGRLRWQGQEWSIVKAPWMIKSGMMLRLRSD
                     SGKRQHLWLAADSMDEAEWRDLRRILLQQETQR"
     gene            complement(9483..10004)
                     /gene="fldB"
                     /locus_tag="IRB70_003331"
     CDS             complement(9483..10004)
                     /gene="fldB"
                     /locus_tag="IRB70_003331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldB"
                     /protein_id="HBC0633207.1"
                     /translation="MNMGLFYGSSTCYTEMAAEKIRDIIGPELVTLHNLKDDSPKLME
                     QYDVLILGIPTWDFGEIQEDWEAVWDQLDDLNLEGKIVALYGLGDQLGYGEWFLDALG
                     MLHDKLSTKGVKFVGYWPTEGYEFTSPKPVIADGQLFVGLALDETNQYDLSDERIQSW
                     CEQILNEMAEHYA"
     gene            10116..11012
                     /gene="xerD"
                     /locus_tag="IRB70_003332"
     CDS             10116..11012
                     /gene="xerD"
                     /locus_tag="IRB70_003332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBC0633208.1"
                     /translation="MKQDLARIEQFLDALWLEKNLAENTLNAYRRDLSMMVEWLHHRG
                     LTLATAQSDDLQALLAERLEGGYKATSSARLLSAVRRLFQYLYREKFREDDPSAHLAS
                     PKLPQRLPKDLSEAQVERLLQAPLIDQPLELRDKAMLEVLYATGLRVSELVGLTMSDI
                     SLRQGVVRVIGKGNKERLVPLGEEAVYWLETYLEHGRPWLLNGVSIDVLFPSQRAQQM
                     TRQTFWHRIKHYAVLAGIDSEKLSPHVLRHAFATHLLNHGADLRVVQMLLGHSDLSTT
                     QIYTHVATERLRQLHQQHHPRA"
     gene            11037..11747
                     /gene="dsbC"
                     /locus_tag="IRB70_003333"
     CDS             11037..11747
                     /gene="dsbC"
                     /locus_tag="IRB70_003333"
                     /EC_number="5.3.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional protein-disulfide
                     isomerase/oxidoreductase DsbC"
                     /protein_id="HBC0633209.1"
                     /translation="MKKGFMLFTLLAAFSGFAQADDAAIQQTLAKMGIKSSDIQPAPV
                     AGMKTVLTNSGVLYITDDGKHIIQGPMYDVSGTAPVNVTNKMLLKQLNALENEMIVYK
                     APQEKHVITVFTDITCGYCHKLHEQMADYNALGITVRYLAFPRQGLESQAEQQMKAIW
                     CAKDKNKAFDDVMAGKAATPASCDIDIADHYALGVQLGVSGTPAIVLSNGTLVPGYQP
                     PKDMKEFLDEHQKMTSGK"
     gene            11753..13486
                     /gene="recJ"
                     /locus_tag="IRB70_003334"
     CDS             11753..13486
                     /gene="recJ"
                     /locus_tag="IRB70_003334"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBC0633210.1"
                     /translation="MKQQIQLRRREVDETADLPAELPPLLRRLYASRGVRSAQELERS
                     VKGMLPWQQLSGVEKAVEILYNAFREGTRIMVVGDFDADGATSTALSVLAMRSLGCSN
                     IDYLVPNRFEDGYGLSPEVVDQAHARGAQLIVTVDNGISSHAGVEHARSLGIPVIVTD
                     HHLPGETLPAAEAIINPNLRDCNFPSKSLAGVGVAFYLMLALRTFLRDQGWFDERGIA
                     IPNLAELLDLVALGTVADVVPLDANNRILTWQGMSRIRAGKCRPGIKALLEVANRDAQ
                     KLAASDLGFALGPRLNAAGRLDDMSVGVALLLCDNIGEARVLANELDALNQTRKEIEQ
                     GMQVEALTLCEKLERSRDTLPGGLAMYHPEWHQGVVGILASRIKERFHRPVIAFAPAG
                     DGTLKGSGRSIQGLHMRDALERLDTLYPGMMLKFGGHAMAAGLSLEEDKFELFQQRFG
                     ELVTEWLDPSLLQGEVVSDGPLSAAEMTMEVAQLLRDAGPWGQMFPEPLFDGHFRLLQ
                     QRLVGERHLKVMVEPVGGGPLLDGIAFNVDTALWPDNGVREVQLAYKLDINEFRGNRS
                     LQIIIDNIWPI"
     gene            13577..14675
                     /gene="prfB"
                     /locus_tag="IRB70_003335"
     CDS             join(13577..13651,13653..14675)
                     /gene="prfB"
                     /locus_tag="IRB70_003335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311790.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBC0633211.1"
                     /translation="MFEINPVNNRIQDLTERSDVLRGYLDYDAKKERLEEVNAELEQP
                     DVWNEPERAQALGKERSSLEAVVDTLDQMKQGLEDVSGLLELAVEADDEETFNEAVAE
                     LDALEEKLAQLEFRRMFSGEYDSADCYLDIQAGSGGTEAQDWASMLERMYLRWAESRG
                     FKTEIIEESEGEVAGIKSVTIKISGDYAYGWLRTETGVHRLVRKSPFDSGGRRHTSFS
                     SAFVYPEVDDDIDIEINPADLRIDVYRASGAGGQHVNRTESAVRITHIPTGIVTQCQN
                     DRSQHKNKDQAMKQMKAKLYELEMQKKNAEKQAMEDNKSDIGWGSQIRSYVLDDSRIK
                     DLRTGVETRNTQAVLDGSLDQFIEASLKAGL"
     gene            14685..16202
                     /gene="lysS"
                     /locus_tag="IRB70_003336"
     CDS             14685..16202
                     /gene="lysS"
                     /locus_tag="IRB70_003336"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001740376.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBC0633212.1"
                     /translation="MSEQHAQGADAVVDLNNELKTRREKLANLREQGIAFPNDFRRDH
                     TSDQLHAEFDGKENEELEALNIEVAVAGRMMTRRIMGKASFVTLQDVGGRIQLYVARD
                     DLPEGVYNEQFKKWDLGDILGAKGKLFKTKTGELSIHCTELRLLTKALRPLPDKFHGL
                     QDQEARYRQRYLDLISNDESRNTFKVRSQILSGIRQFMVNRGFMEVETPMMQVIPGGA
                     AARPFITHHNALDLDMYLRIAPELYLKRLVVGGFERVFEINRNFRNEGISVRHNPEFT
                     MMELYMAYADYKDLIELTESLFRTLAQDILGKTEVTYGDVTLDFGKPFEKLTMREAIK
                     KYRPETDMADLDNFDSAKAIAESIGIHVEKSWGLGRIVTEIFEEVAEAHLIQPTFITE
                     YPAEVSPLARRNDVNPEITDRFEFFIGGREIGNGFSELNDAEDQAQRFLDQVAAKDAG
                     DDEAMFYDEDYVTALEHGLPPTAGLGIGIDRMVMLFTNSHTIRDVILFPAMRPVK"
     gene            complement(16245..16793)
                     /gene="idi"
                     /locus_tag="IRB70_003337"
     CDS             complement(16245..16793)
                     /gene="idi"
                     /locus_tag="IRB70_003337"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBC0633213.1"
                     /translation="MQTEHVILLNAQGVPTGTLEKYAAHTADTLLHLAFSSWLFNAKG
                     QLLVTRRALSKKAWPGVWTNSVCGHPQLGESNEDAVIRRCRYELGVEITPPESIYPDF
                     YYRATDPNGIVENEVCPVFAARTTSALQINDDEVMDYQWCDLADVLHGIDATPWAFSP
                     WMVMQAANSEARKLLSAFAQHN"
     gene            16848..16919
                     /locus_tag="IRB70_003338"
     CDS             16848..16919
                     /locus_tag="IRB70_003338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633214.1"
                     /translation="MINQVSVYRQPPVLSGCRQVKTI"
     gene            complement(16916..17041)
                     /locus_tag="IRB70_003339"
     CDS             complement(16916..17041)
                     /locus_tag="IRB70_003339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633215.1"
                     /translation="MNLLMRAIFSLLLLFTLSIPVISDCVAMAIESRFKYMMLLF"
     gene            complement(17043..18481)
                     /gene="uacT"
                     /locus_tag="IRB70_003340"
                     /pseudo
     CDS             complement(17043..18481)
                     /gene="uacT"
                     /locus_tag="IRB70_003340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417364.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="urate/proton symporter UacT"
     gene            18917..20836
                     /gene="ygfT"
                     /locus_tag="IRB70_003341"
     CDS             18917..20836
                     /gene="ygfT"
                     /locus_tag="IRB70_003341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417363.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate-dependent uric acid utilization protein
                     YgfT"
                     /protein_id="HBC0633216.1"
                     /translation="MNKFIAAEAAECIGCHACEIACAMAHNQENWPLSHSDFRPRIHV
                     VGKGQAANPVACHHCNNAPCVTACPVNALTFQPDSVQLDEQKCIGCKRCAIACPFGVV
                     EMVDTIAQKCDLCNQRSSGTQACIEVCPTQALRLMDDKGLQQIKVARQRKTAAGKASS
                     DAQPSRSAALLPINSRKGADKISASERKTHFGEIYCGLDPQQATYESDRCVYCAEKAN
                     CNWHCPLHNAIPDYIRLVQEGKIIEAAELCHQTSSLPEICGRVCPQDRLCEGACTLKD
                     HSGAVSIGNLERYITDTALAMGWRPDVSMVVPRSEKVAVIGAGPAGLGCADILVRAGV
                     QVDVFDRHPEIGGMLTFGIPPFKLDKTVLSQRREIFTAMGIDFHLNCEIGRDITFSDL
                     TSEYDAVFIGVGTYGMMRADLPHEDVPGVIQALPFLTAHTRQLMGLPESEEYPLTDVE
                     GKRVVVLGGGDTTMDCLRTSIRLNAASVTCAYRRDEVSMPGSRKEVVNAREEGVEFQF
                     NVQPQYIACDEDGRLTAVGLIRTAMGEPGPDGRRRPRPVAGSEFELPADVLIMAFGFQ
                     AHAMPWLQGSGIKLDKWGLIQTGDVGYLPTQTHLKKVFAGGDAVHGADLVVTAMAAGR
                     QAARDMLTLFDTKAS"
     gene            20836..21324
                     /locus_tag="IRB70_003342"
     CDS             20836..21324
                     /locus_tag="IRB70_003342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417362.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S dicluster domain-containing protein"
                     /protein_id="HBC0633217.1"
                     /translation="MKSLIIVNPADCIGCRTCEVACVVAHPSEQELNADVFLPRLKVQ
                     RLDSISAPVMCHQCENAPCVSACPVGALTMGEQVVQTNSARCIGCQSCVSACPFGMIT
                     IQSLPGDTRQQIVKCDLCEQREEGPACVESCPTQALQLLTERELRRVRQQRIVASGEN
                     PL"
     gene            complement(21360..22727)
                     /gene="ghxQ"
                     /locus_tag="IRB70_003343"
                     /gene_synonym="ygfQ"
     CDS             complement(21360..22727)
                     /gene="ghxQ"
                     /locus_tag="IRB70_003343"
                     /gene_synonym="ygfQ"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxQ"
                     /protein_id="HBC0633218.1"
                     /translation="MSGDILQTPDAPKPQGALDNYFKITARGSTVRQEVLAGLTTFLA
                     MVYSVIVVPGMLGKAGFPPAAVFVATCLVAGFGSLLMGLWANLPMAIGCAISLTAFTA
                     FSLVLGQQISVPVALGAVFLMGVIFTAISVTGVRTWILRNLPMGIAHGTGIGIGLFLL
                     LIAANGVGMVIKNPIEGLPVALGAFTSFPVMMSLLGLAVIFGLEKCRVPGGILLVIIA
                     ISIIGLIFDPAVKYHGLVAMPSLTGEDGKSLIFSLDIMGALQPTVLPSVLALVMTAVF
                     DATGTIRAVAGQANLLDKDNQIINGGKALTSDSVSSIFSGLVGAAPAAVYIESAAGTA
                     AGGKTGLTATVVGALFLLILFLSPLSFLIPGYATAPALMYVGLLMLSNVSKLDFNDFI
                     DAMAGLVCAVFIVLTCNIVTGIMLGFVTLVVGRVFAREWQKLNIGTVIITAALVAFYA
                     GGWAI"
     gene            complement(22763..24079)
                     /gene="guaD"
                     /locus_tag="IRB70_003344"
     CDS             complement(22763..24079)
                     /gene="guaD"
                     /locus_tag="IRB70_003344"
                     /EC_number="3.5.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine deaminase"
                     /protein_id="HBC0633219.1"
                     /translation="MSGEHTLKAVRGSFIDVTRTVDNPEEIASALRFIEDGLLLIKQG
                     KVEWFGEWENGKHQIPDTIRVRDYRGKLIVPGFVDTHIHYPQSEMVGAYGEQLLEWLN
                     KHTFPTERRYEDLEYAREMSAFFIKQLLRNGTTTALVFGTVHPQSVDALFEAASHINM
                     RMIAGKVMMDRNAPDYLLDTAESSYHQSKELIERWHKNGRLLYAITPRFAPTSSPEQM
                     AMAQRLKEEYPDTWVHTHLCENKDEIAWVKSLYPDHDGYLDVYHQYGLTGKNCVFAHC
                     VHLEEKEWDRLSETKSSIAFCPTSNLYLGSGLFNLKKAWQKKVKVGMGTDIGAGTTFN
                     MLQTLNEAYKVLQLQGYRLSAYEAFYLATLGGAKSLGLDDLIGNFLPGKEADFVVMEP
                     TATPLQQLRYDNSVSLVDKLFVMMTLGDDRSIYRTYVDGRLVYERN"
BASE COUNT         5936 a         6086 c         6429 g         5699 t
ORIGIN      
        1 attctgttgc gatttttgca ttttttaacc ataagctaat gtgatgatca attttacctt
       61 atggttaaca gtctgtttcg gtggtaagtt caggcaaaag agaacgattg cgttggggac
      121 cgggagtggc tccgatgctg ggtttcgtgg tgataatttc gccatggaaa agttgtcagc
      181 cccgcttatt caatgaggac aagatggcac aacagactcc tttgtacgaa caacacacgc
      241 tttgcggcgc tcgcatggtg gatttccacg gctggatgat gccgctgcat tacggttcgc
      301 aaatcgacga acatcatgcg gtacgtaccg atgccggaat gtttgatgtg tcacatatga
      361 ccatcgtcga tcttcgcggc agccgcactc gggagtttct gcgttatctg ctggcgaacg
      421 atgtggcgaa actcaccaaa agcggcaaag ccctttactc ggggatgttg aatgcctctg
      481 gcggtgtgat agatgacctc atcgtctact actttactga agatttcttc cgcctcgttg
      541 ttaactccgc cacccgcgaa aaagacctct cctggattac ccaacacgct gaacctttcg
      601 gcatcgaaat taccgttcgt gatgaccttt ccatgatcgc cgtacaaggg ccgaatgcgc
      661 aggcaaaagc tgccacactg tttaatgacg cccagcgtca ggcggtggaa gggatgaaac
      721 cgttctttgg cgtgcaggcg ggcgatctgt ttattgccac cactggttat accggtgaag
      781 cgggctatga aattgcgctg cccaatgaaa aagcggcgga tttctggcgc gcgctggtgg
      841 aagcgggcgt taagccatgc ggcctgggcg cgcgtgacac gctgcgtctg gaagcgggta
      901 tgaatcttta tagtcaggag atggacgaaa ccatctctcc tttagccgcc aatatgggct
      961 ggactatcgc ctgggaaccg gcagatcgtg acttcatcgg tcgtgaagcc ctggaagtgc
     1021 agcgtgagca tggcacagaa aaactggttg gtctggtgat gaccgaaaaa ggcgtgctgc
     1081 gtaatgaact gccggtacgc tttaccgatg cgcagggcaa ccagcatgaa ggcattatca
     1141 ccagcggtac tttctccccg acgctgggtt acagcattgc gctggcgcgc gtgccggaag
     1201 gtattggtga aacagcgatt gtacaaattc gcaaccgtga aatgccggtt aaagtgacga
     1261 aacctgtttt tgtgcgtaac ggtaaagccg tcgcgtgatt tacttttttg gagattgatt
     1321 gatgagcaac gtaccagcag aactgaaata cagcaaagaa cacgaatggc tgcgtaaaga
     1381 agccgacggc acttacaccg ttggtatcac cgaacatgcc caggagctgt taggcgatat
     1441 ggtgtttgtt gacctgccgg aagtgggcgc aacggttagc gcgggcgatg actgcgcggt
     1501 tgccgaatca gtaaaagcgg cgtcagacat ttatgcgcca gtaagcggtg aaatcgtggc
     1561 ggtaaacgac gcactgagcg attccccgga actggtgaac agcgaaccgt atgcaggcgg
     1621 ctggatcttt aaaatcaaag ccagcgatga aagcgaactg gaatcactgc tggatgcgac
     1681 cgcatacgaa gcattgttag aagacgagta acggctttat tcctcttctg cgggagagga
     1741 tcagggtgag gaacttttac gcctcaccct cactctcttc gcaaggagag aggttcacaa
     1801 ttcactgcac gtttcaggaa ccatcgctca tgacacagac gttaagccag cttgaaaaca
     1861 gcggcgcttt tattgaacgc catatcggac cggacgccgc gcaacagcaa gaaatgctga
     1921 atgccgttgg cgcacaatcg ttaaacgcgc tgaccggcca gattgtgccg aaagatattc
     1981 agcttgcgac cccgccgcag gttggcgcac cggcgaccga atacgccgcg ctggcggaac
     2041 tcaaggctat tgccagtcgc aataaacgct tcacgtctta catcggcatg ggttacaccg
     2101 ccgtgcagct accgccggtt attctgcgta acatgctgga aaatccgggc tggtataccg
     2161 cgtatactcc gtatcaacct gaagtctccc agggccgcct tgaagcactg ctcaacttcc
     2221 agcaggtaac gctggatttg accgggctgg atatggcctc tgcctctctt ctggacgagg
     2281 ccactgctgc cgccgaagca atggcgatgg cgaaacgcgt cagcaaactg aaaaatgcca
     2341 accgcttctt cgttgcttct gacgttcatc cgcaaacgct cgatgtggtc cgtactcgtg
     2401 ctgaaacctt tggttttgaa gtgattgtcg atgacgcgca aaaagtgctc gaccatcagg
     2461 acgtcttcgg cgtgctgtta cagcaggttg gcacaaccgg tgaaatccac gactacactg
     2521 cgctcatcag cgaactgaaa tcacgcaaaa ttgtggtcag tgtcgccgcc gatattatgg
     2581 cgctggtgct gttaactgcg ccgggtaaac agggcgcgga tattgtcttt ggttcggcgc
     2641 aacgcttcgg tgtgccgatg ggctacggtg gcccacacgc agcattcttt gcggcgaaag
     2701 atgaatacaa acgctcaatg ccgggccgta ttatcggtgt atcgaaagat gcagctggca
     2761 ataccgctct gcgcatggcg atgcagactc gcgagcaaca tattcgccgt gagaaagcga
     2821 actccaacat ttgtacttcc caggtactgc tggcaaacat cgccagcctg tatgccgttt
     2881 atcacggccc ggttggcctg aaacgtatcg ctaaccgcat ccaccgtctg accgatatcc
     2941 tggcggcggg cctgcaacaa aaaggtctga aactgcgtca tgcgcactat ttcgacactt
     3001 tgtgtgtgga agtggcagac aaggcgggcg tactggcgcg tgccgaagcg gctgaaatca
     3061 acctgcgtag cgatatcctg aacgcggttg ggatcaccct tgatgaaacc accacgcgtg
     3121 aaaacgtgat gcagcttttc agcgtactgc tgggggataa ccacggcctg gacatcgaca
     3181 cgctggacaa agacgtggct cacgacagcc gctctattca gcctgcgatg ctgcgcgacg
     3241 tcgaaatcct cacccatccg gtgtttaatc gctaccacag cgaaaccgaa atgatgcgct
     3301 atatgcactc gctggagcgt aaagatctgg cgctgaatca ggcgatgatc ccgctgggtt
     3361 cctgcaccat gaaactgaac gccgccgccg agatgatccc aatcacctgg ccggaatttg
     3421 ccgaactgca cccgttctgc ccgccggagc aggccgaagg ttatcagcag atgattgcgc
     3481 agctggctga ctggctggtg aaactgaccg gttacgacgc cgtttgtatg cagccgaact
     3541 ctggcgcaca gggcgaatac gcgggcctgc tggcgattcg tcattatcat gaaagccgca
     3601 acgaagggca tcgtgatatc tgcctgatcc cggcttctgc gcacggaact aaccccgctt
     3661 ctgcacatat ggcaggaatg caggtggtgg ttgtggcgtg tgataaaaac ggcaacatcg
     3721 atctgactga tctgcgcgcg aaagcggaac aggcgggcga taacctctcc tgtatcatgg
     3781 tgacctatcc ttccacccac ggcgtgtatg aagaaacgat ccgtgaagtg tgtgaagtcg
     3841 tgcatcagtt cggcggtcag gtttaccttg atggcgcgaa catgaacgcc caggtcggca
     3901 tcacctcacc gggctttatt ggcgcggacg tctcgcacct taacctgcat aaaactttct
     3961 gcattccgca cggtggcggc ggccctggta tgggaccgat cggcgtgaaa gcgcatctgg
     4021 caccgtttgt gccaggtcat agcgtggtac aaattgaagg catgttaacc cgtcagggcg
     4081 cggtttctgc ggcaccgttc ggtagcgcat ccattctgcc aatcagctgg atgtacatcc
     4141 gcatgatggg cgcagaaggg ctgaaaaaag caagccaggt ggcaattctt aacgccaact
     4201 atattgccag ccgcctgcag gatgccttcc cggtgctgta taccggtcgc gacggtcgcg
     4261 tggcgcacga atgtattctc gatattcgcc cgctgaaaga agaaaccggc atcagcgaac
     4321 tggatattgc caagcgtctg atcgactacg gtttccacgc gccgaccatg tcgttcccgg
     4381 tggcgggtac gctgatggtt gaaccgactg aatctgaaag caaagtggaa ctggatcgct
     4441 ttatcgacgc gatgctggct atccgcgcag aaattgacca ggtgaaagcc ggtgtctggc
     4501 cgctggaaga taacccgctg gtgaacgcgc cgcacattca gagcgaactg gtcgccgagt
     4561 gggcgcatcc gtacagccgt gaagttgcgg tattcccggc aggcgtggca gacaaatact
     4621 ggccgacagt gaaacgtctg gatgatgttt acggcgaccg taacctgttc tgctcctgcg
     4681 taccgattag cgaataccag taattcactg attcgactat cttctaaagg cgcttcggcg
     4741 cctttttagc ttgttaataa agtgcgcttt gtgtgtcgga tgaagcgtaa atataaactc
     4801 ctggagttca atatatgaca ggagcgccag gcctgatgag cggggcgcat caggcacatc
     4861 gggtaattaa agattctcgc cgttgctggc aatcacctct ttgtaccagt caaagctctt
     4921 cttacgtgaa cgcgacatat cgccagtacc gtcgtcatgt ttattcacat agataaagcc
     4981 gtagcgtttg ctgtactgcc cggtggtaaa cgacacgcag tcgatgcagc cccacggtgt
     5041 gtagcccatc agatccacgc catcgtaagt caccgctttt ttcatctctt caatatgggc
     5101 gcgcaggtag tcaatgcggt agtcgtcgtt gatgctgcca tcttcttcca ctttgtcata
     5161 agcgccaaaa ccgttttcga caataaacag cggcttctga taacgctcat acagttcgca
     5221 aagtgcgtaa cgcagaccca caggatcaat ctgccagccc cagtcagacg ctttaacata
     5281 cgggtttggt acgctgcctt caaaaccaga gatcgcatcg ccggtgccgc cttcggcctt
     5341 caccgcgttg gtcatgtaat agctgaaacc gagataatcg caggtgcctt cgcgcagcac
     5401 atcgagatcg ccgtcttcca ttttgatgtt aaatccgcga cgctcccact cgttcaacac
     5461 ataggacggg taatagccac gcagttgcac atcggtaaag acgtagcgtt cgcgcatcga
     5521 ctcctgggcg aacatcacat cgtccggatt acaggagtaa gggtagagcg gcaccatcgc
     5581 cagcatacag ccgactttca tttccgggtt aatgcgacgc gcggctttca ccgccagggc
     5641 gctggcgaca aactggtgat gcagcacctg gtacatcgtc tcttccgggt tttcatgctc
     5701 ggtatacacc acgccggagc agcagtaacc gaacagcggt gcacgccagt tacgctggtt
     5761 gttaatttcg ttgaaggtca tccagtattt gactttatgc ttatagcgtt caaataccac
     5821 ttctgcgaaa cggacaaaga aatcaaccac tttacggttg gtccagctac cgtattgctg
     5881 caccagatgc agcggcattt caaagtggga gagggtgatc accggttcga tgttgtattt
     5941 cagcagttca tcgaacatat catcgtagaa cttcagccct tcttcgtttg gctgagcttc
     6001 atcgcctttt ggaaaaatgc gcgtccaggc gatggatgta cgaaaacatt tgaagcccat
     6061 ttcggcaaat agcttgatgt cttccttgta atgaccataa aaatcaacgg cttcatggtt
     6121 cggatagtat tttcctggca acacttcttt ggtgatttcg cgcggcacgc tgtgtgcgcc
     6181 accggtcaga acgtcacaaa tgctcggccc tttgccgcct ttgttccagc cgccttcgac
     6241 ctgatgagcg gcaactgcgc cgccccataa gaaatctttc ggtaaggtga gttttttcac
     6301 tatcataggc tccagatgag tcaattctta caggaaatag taccatgcag ccaaacgaca
     6361 tcactttttt tcaacgtttc caggatgaca ttctggctgg gcgtaaaacc atcaccatcc
     6421 gcgacgagtc tgaatcgcac ttcaaaacgg gtgatgtgct tcgtgtcggg cgttttgaag
     6481 atgacggtta tttttgcacg attgaagtca ccgcaacctc aaccgtaacg ctggatacac
     6541 tgacggaaaa acatgcagag caggaaaata tgaccctgac tgatctgaaa aaggtcatta
     6601 ccgatatcta tcccggtcag acacagtttt atgtgattga atttaaatgc ctttaaattg
     6661 aactcacgcc tgttagttga aatttcgcat ttaatttcat gatttttcgg agattagtct
     6721 caaatcagaa tttattttag ctaacaggtg ttcactggaa ctattctcag ttacgctgga
     6781 gaggtataca tgtgcgtgta cgtttctccg gagtaagtta tggttcagaa gcccctcatt
     6841 aagcagggat attcgctggc agaggaaatt gccaacagcg tcagtcacgg cattgggttg
     6901 gtgtttggta tcgttgggct ggtgttgcta ctggttcaag cggtggatct caatgccagc
     6961 gccacagcga taaccagtta cagcctctat ggcggcagta tgatcctgct gttcctcgct
     7021 tcgacgctct atcacgccat tcctcatcaa cgggcaaaaa tgtggctgaa gaaatttgac
     7081 cattgcgcta tttacctatt gattgccgga acctacacgc cgtttttgct ggtggggctg
     7141 gattctccgt tagcgcgcgg gttgatgatt gttatctgga gcctggcatt gctggggatt
     7201 ctgttcaaac tgaccatcgc gcaccgattc aaaattttat ctctggtgac ctatctggcg
     7261 atgggctggc tgtcgctggt ggtgatttat gaaatggcaa ttaagcttgc ggcgggcagc
     7321 gttaccttac tggctgtagg cggcgtggtt tactcgctcg gggtgatttt ctacgtctgc
     7381 aaacgcattc cctacaacca tgccatctgg cacggctttg tgctcggcgg cagcgtgtgc
     7441 cactttctgg cgatctattt atatattggg caggcgtaat gggtgtgcct ttgtaggcct
     7501 gaaaagacac acccttgtcg catcaggcga taaatgcatg atgcgacaca gagatttact
     7561 cttcgagtga atacggcagc ggctcgatat gcaatgtatt cgcatcgtca cgcacgcgga
     7621 agatgctgtc cggttccata tcgttattca tgacgacctg taccacgacc tgaccatctt
     7681 ccagttttac cgcagccagc acggttccgg tacgacgcca gttctcgccc attttcagct
     7741 ctaagtcttc accggcttcc ggcagtcggc tggcgctacc cgtcagcaac cagagcgcgc
     7801 gtttattggc accacggaat ttagctcgcg ccaccatctc ttgtccggta tagcagcctt
     7861 ttttaaagct aatgccgccc agcgcctgga ggttggtcgc ctgtgggata aactgcccgc
     7921 tgttggcggc atcaatcacc gggaaacccg cttcaatgtt taatgccagc cactgttggc
     7981 tattgttcag ttccgcttca ccgcgcagtt tatcggtcag catattggca gtggcttcat
     8041 cggttacgat caggaaacgt tctgcagggt gttcaaacca tagcaaagtg gtcgcgcctt
     8101 ctttaactac ctgtttttct ttcgaaggca gttcactaaa gatatttgcc agcgcggcgc
     8161 gcgcctgaaa accggcaaca ccaagcagca cacgctcatc gtccggcgcg atggtcactt
     8221 tagagaacac cgcatatttt ttcagttcag tcagctgcgg ttcacgcaca ctgcgccgtt
     8281 caatccatgc aaagccatcg ccgtcgcgga acagacgtaa attgctccac attttacctt
     8341 tggcgtcgca atgggcggcg agcagatgct gattttctgt catctggctg acatctgctg
     8401 tcacctgacc ctgcatatat ttttcgctgt ccgcgccagt aatggtggca agcgcccagt
     8461 catcaagcgt tatcagcgtc agcggtaaac gggcagacgc cgtaggctga cggggaggaa
     8521 aaggtgtaaa agccataata gagtcctgag ttgcttaacg gcgtattaat gactaatggt
     8581 aaaagagcta tgaggcaatg caagtgcttt cactacgcga tctgtgcctt ctgatatgct
     8641 ttgcgaggcg acttccaaaa aaatgaagcc cttgaattgt tgtgaattaa tttcgcgatc
     8701 gcgattgtgt ttactgatat tcccgtaaaa gaagtcgaaa aacacgttac aatagccggg
     8761 tactggattt tcgtgagaca ggaagaagat ggacattaac aacaaagccc gcattcattg
     8821 ggcatgccgc cgtggtatgc gcgaactcga tatttcaatc atgccgtttt tcgaacatga
     8881 gtacgacagc ttaagcgatg acgaaaaacg catctttatt cgtctgctgg aatgtgacga
     8941 tccggacctg tttaactggc tgatgaatca cggtaaacca gccgatgcag aactggaaat
     9001 gatggtccga ctcatccaga cacggaaccg ggaacgtggt cctgtggcaa tctgatttgc
     9061 gcgtctcctg gcgcgcacag tggctttcct tgctgattca tgggctggtt gccgctgtta
     9121 ttttactcat gccctggccg ctcagttaca ccccgttatg gatggtgtta ctttcgctgg
     9181 tggtgtttga ttgcgttcgc agccagcggc gcattaatgc tcgccagggg gaaattcgct
     9241 tgttgatgga cgggcgtttg cgttggcaag ggcaggagtg gagcatcgtc aaagcgccgt
     9301 ggatgattaa gagcggcatg atgctgcgtt tacgttctga cagcggaaaa cggcaacatt
     9361 tatggctggc agctgacagc atggacgaag ccgaatggcg ggatttacgg cggatattgt
     9421 tacaacaaga gacgcaaaga taaagatgac ggcaaagcat atgtgctaag ccgtcagtga
     9481 catcaggcgt aatgctctgc catttcgttg aggatttgct cgcaccagct ctgaatacgc
     9541 tcgtcgctaa ggtcatactg gttagtttca tccagcgcca gacccacgaa cagttgcccg
     9601 tcagcaatca ccggtttcgg gctggtaaat tcatatcctt ccgttggcca gtagccgacg
     9661 aacttcacgc ctttggtcga gagtttgtca tgcagcatac cgagcgcatc gaggaaccac
     9721 tcgccgtatc ccagttgatc gccaagccca tacagcgcaa caattttacc ttcgaggttc
     9781 aggtcgtcga gctgatccca gacggcttcc cagtcttcct ggatttcgcc aaaatcccag
     9841 gtcgggatac ccagaatgag cacatcgtac tgctccatta atttcgggga gtcgtccttg
     9901 aggttatgta aggtcaccag ttctgggccg ataatatcgc ggattttttc tgccgccatt
     9961 tcggtgtaac aggtgctgga accgtaaaaa agacccatat tcataacgta agcttctcga
    10021 ttctgctgtg gcttttgcgg ctagtgtatc agaatcgctt tagtcacggc acaataaggc
    10081 ataatggatc aaatgagtga ccataagggg cgcaagtgaa acaggatctg gcacgcatcg
    10141 agcagtttct tgatgctctg tggctggaaa aaaatctggc tgaaaatacg ttgaacgctt
    10201 accgtcgcga tctgtcaatg atggtggagt ggttgcatca ccgcgggttg acgctggcga
    10261 cggcgcaaag tgacgatttg caggcattac tggcagaacg gctggagggc gggtataaag
    10321 ccaccagctc agcgcgtttg ctgagtgcag tgcgccgatt gttccagtat ctttatcgcg
    10381 aaaagtttcg tgaagatgat cccagtgcgc atctcgcttc accgaaattg ccccagcgtt
    10441 tgccaaaaga tttaagcgaa gcgcaggtcg aacgtttatt acaggcacca ttaattgatc
    10501 agccactgga gctacgcgat aaagccatgc ttgaagtgtt gtatgctacc ggactgcgtg
    10561 tctctgaact ggtcgggctg acaatgagtg atatcagcct gcgtcagggc gtggtgcggg
    10621 tcattggtaa aggcaacaaa gagcgcctgg tgccgttagg tgaagaggcg gtttactggc
    10681 tggaaaccta tctggaacat gggcgtccgt ggctgttgaa tggtgtgtca attgacgtgt
    10741 tgtttcccag ccagcgtgcg cagcagatga cgcgacagac cttctggcac cgcattaaac
    10801 attatgccgt gctggcgggt atcgacagcg aaaagctgtc accgcatgtg ttgcgtcacg
    10861 cttttgccac tcacttatta aatcatggtg cggatttgcg cgtggtgcag atgctactgg
    10921 gccacagcga tctctccacc acgcaaattt atacgcatgt cgctaccgag cgtctgcggc
    10981 aacttcatca acagcatcac ccgcgggcgt gatgtctgaa aagaacggga agatttatga
    11041 agaaaggttt tatgttattt acgttgttgg cggcgttttc aggctttgct caggcggatg
    11101 acgcggcaat tcaacagacg ttagccaaaa tgggcatcaa aagcagcgat attcagcctg
    11161 cacccgtggc tggcatgaag acagttctga ctaacagcgg tgtgttgtac atcaccgatg
    11221 atggtaaaca tatcattcag gggccaatgt atgacgttag cggaacggca ccggtcaatg
    11281 tcaccaataa gatgctgtta aagcagctga acgcgcttga aaacgagatg atcgtttata
    11341 aagcgccgca ggaaaaacac gtcattaccg tgtttactga tattacctgt ggttactgcc
    11401 acaaactgca tgagcaaatg gcagactaca acgcgctggg gatcaccgtg cgttatcttg
    11461 ctttcccgcg ccaggggctg gagagccagg ctgagcaaca aatgaaagcc atctggtgtg
    11521 cgaaagataa aaacaaagcg tttgatgatg tgatggctgg taaagctgcc actccggcaa
    11581 gttgcgatat cgatattgcc gatcattacg cacttggcgt ccagcttggc gttagcggca
    11641 ctccggcaat tgtgctgagc aatggcacac ttgttccggg ttaccagcca ccgaaagaca
    11701 tgaaagaatt cctcgacgaa caccaaaaaa tgaccagcgg taaataattc gcgtgaaaca
    11761 acagatacaa cttcgtcgcc gtgaagtcga tgaaacggca gacttgcccg ctgaattgcc
    11821 gcccttgctg cgccgtttat acgccagccg gggagtacgc agtgcgcaag aactggaacg
    11881 cagtgttaaa ggtatgctgc cctggcagca actgagcggc gtcgaaaagg ccgttgagat
    11941 cctttacaac gcctttcgcg aaggaacgcg gattatggtg gtcggtgatt tcgacgccga
    12001 cggtgccacc agcacggctc taagcgtgct ggcgatgcgc tcgcttggtt gcagcaatat
    12061 cgactacctg gtaccaaacc gtttcgaaga cggttacggc ttaagcccgg aagtggtcga
    12121 tcaggcccat gcccgtggcg cgcagttaat tgtcacggtg gataacggta tttcctccca
    12181 tgcgggggtt gaacacgctc gctcgttggg cattccggtt attgttaccg atcaccattt
    12241 gccgggcgaa accttacccg cggcggaagc gatcattaac cctaacttgc gcgactgtaa
    12301 tttcccgtcg aaatcactgg caggcgtggg ggtagcgttt tatctgatgc tggcgctgcg
    12361 cacctttttg cgcgatcagg gctggtttga tgagcgcggc atcgcaattc ctaatctggc
    12421 agaactgctg gatctggtag cgttggggac agtggcggac gtcgtgccgc tggacgctaa
    12481 taaccgcatc ctcacctggc aggggatgag ccgcatacgc gccggaaaat gccgtccagg
    12541 aattaaagcg ctgctggaag tggcaaaccg tgatgcacaa aaactcgccg ccagcgatct
    12601 aggttttgcg ctggggccgc gtctgaatgc agccgggaga ctggatgata tgtccgttgg
    12661 tgtggcgctg ttgctgtgcg acaacatcgg cgaagcgcgc gtgctggcaa atgaactcga
    12721 tgcgctaaac cagacgcgaa aagagatcga acagggaatg caggttgaag ccctgaccct
    12781 gtgcgagaaa ctggagcgca gccgcgacac gctacccggc gggctggcaa tgtatcaccc
    12841 cgaatggcat cagggcgttg tcggtattct ggcttcgcgc atcaaagagc gttttcatcg
    12901 tccggttatc gcctttgcgc cagctggtga tggtacgctg aaaggttccg gtcgctcgat
    12961 tcaggggcta cacatgcgcg atgcgctgga gcggttagac acgctctacc ctggcatgat
    13021 gctcaagttt ggcggtcatg cgatggcggc gggtttgtcg ctggaagagg ataaattcga
    13081 actctttcaa caacggtttg gcgaactggt taccgagtgg ttagatcctt ctttattgca
    13141 aggggaagtg gtatcagacg gcccattaag tgcggcagag atgaccatgg aagtggcgca
    13201 actgctgcgt gatgctggcc cgtggggaca aatgttcccg gagccgctgt ttgacggtca
    13261 tttccgtctg ctgcaacagc gactggtggg tgaacgtcat ttgaaagtca tggtcgaacc
    13321 ggtcggcggc ggtccgctgc tggacggtat tgcttttaat gtcgataccg ccctctggcc
    13381 ggataacggc gtgcgcgaag tgcaactggc ttacaagctc gatatcaacg agtttcgcgg
    13441 caaccgcagc ctgcaaatta tcatcgacaa tatctggcca atttagcgtc atcttctcta
    13501 taaaaaagag cgtggattgg gtacaatccc gctcttatca ccgcattttg actagctcaa
    13561 taaaagaaat cagaccatgt ttgaaattaa tccggtaaat aatcgcattc aggacctcac
    13621 ggaacgctcc gacgttctta gggggtatct ttgactatga cgccaagaaa gagcgtctgg
    13681 aagaagtaaa cgccgagctg gaacagccgg atgtctggaa cgaacccgaa cgcgcacagg
    13741 cgctgggtaa agagcgttcc tccctcgaag ccgttgtcga caccctcgac caaatgaaac
    13801 aggggctgga agatgtttct ggtctgctgg aactggctgt agaagctgac gacgaagaaa
    13861 cctttaacga agccgttgct gaactcgacg ccctggaaga aaaactggcg cagcttgagt
    13921 tccgccgtat gttctctggc gaatatgaca gcgccgactg ctacctcgat attcaggcgg
    13981 ggtctggcgg cacggaagca caggactggg cgagcatgct tgagcgtatg tatctgcgct
    14041 gggcagaatc gcgtggtttc aaaactgaaa tcatcgaaga gtcggaaggt gaagtggcgg
    14101 gtattaaatc cgtgacgatc aaaatctccg gcgattacgc ttacggctgg ctgcgtacag
    14161 aaaccggcgt tcaccgcctg gtgcgtaaga gcccgtttga ttccggcggt cgtcgccaca
    14221 cgtcgttcag ctccgcgttt gtttacccgg aagttgatga cgatatcgat atcgaaatca
    14281 atccggcgga tctgcgcatc gacgtttatc gcgcgtccgg cgcgggcggt cagcacgtta
    14341 accgtaccga atctgcggtg cgtattactc acatcccaac tgggatcgtg acccagtgcc
    14401 agaacgaccg ttcccagcac aagaacaaag accaggccat gaagcagatg aaagcgaagc
    14461 tttatgaact ggagatgcag aagaaaaatg ctgagaaaca ggcgatggaa gataacaaat
    14521 ctgacatcgg ctggggcagc cagattcgtt cttatgtcct tgatgactcc cgcattaaag
    14581 atctgcgtac cggggtagaa acccgcaaca cgcaggccgt gctggacggc agcctggatc
    14641 aatttatcga agcaagtttg aaagcagggt tatgaggaac caacatgtct gaacaacacg
    14701 cacagggcgc tgacgcggta gtcgatctta acaatgaact gaaaacgcgt cgtgagaagc
    14761 tggcgaacct gcgtgagcag gggattgcct tcccgaacga tttccgtcgc gatcatacct
    14821 ctgaccaatt gcacgcagaa ttcgacggta aagagaacga agaactggaa gcgctgaaca
    14881 tcgaagtcgc cgttgctggc cgcatgatga cccgtcgtat tatgggtaaa gcgtctttcg
    14941 ttaccctgca ggacgttggc ggtcgcattc agttgtacgt tgcccgtgac gatctgccgg
    15001 aaggcgttta caacgagcag ttcaaaaaat gggacctcgg cgatatcctc ggcgcgaaag
    15061 gtaaactgtt caaaaccaaa accggcgaac tgtctatcca ctgtaccgag ctgcgtctgc
    15121 tgaccaaagc actacgtccg ctgccggata aattccacgg cttgcaggat caggaagcgc
    15181 gctatcgtca gcgttatctg gatctcatct ctaacgatga atcccgcaac acctttaaag
    15241 tgcgctcgca gatcctctct ggtattcgcc agttcatggt gaaccgcggc tttatggaag
    15301 ttgaaacgcc gatgatgcag gtgatccctg gcggtgccgc tgcgcgtccg tttatcactc
    15361 accataacgc gctggatctc gacatgtacc tgcgtatcgc gccggaactg tacctcaagc
    15421 gtctggtggt cggtggcttc gagcgtgtat tcgaaatcaa ccgtaacttc cgtaacgaag
    15481 gtatttccgt acgtcataac ccagagttca ccatgatgga actctatatg gcttacgcag
    15541 attacaaaga tcttatcgag ctgaccgaat cgctgttccg tactctggca caggatattc
    15601 tcggtaagac ggaagtgacc tacggcgacg taacgctgga cttcggtaaa ccgttcgaaa
    15661 aactgaccat gcgtgaagcg atcaagaaat atcgcccgga aaccgacatg gcggatctgg
    15721 acaacttcga ctctgcgaaa gcgattgctg aatctatcgg catccacgtt gagaagagct
    15781 ggggtctggg ccgtatcgtt accgagatct tcgaagaagt ggcagaagca catctgatcc
    15841 agccgacctt cattactgaa tatccggcag aagtttctcc tctggcgcgt cgtaacgacg
    15901 ttaacccgga aatcacagac cgctttgagt tcttcattgg tgggcgtgaa atcggtaacg
    15961 gctttagcga actgaatgac gcggaagatc aggcgcagcg cttcctggat caggttgccg
    16021 cgaaagatgc aggtgacgac gaagcgatgt tctacgatga agattacgtc accgcactgg
    16081 aacatggctt accgccgaca gcaggtctgg gaattggtat cgaccgtatg gtaatgctgt
    16141 tcaccaacag ccataccatc cgcgacgtta ttctgttccc ggcgatgcgt ccggtaaaat
    16201 aagcattacg ttatgctcac aaccccggca aatgtcgggg ttttttaatt gtgctgcgcg
    16261 aaagcagaca acaattttct tgcttcacta ttggctgcct gcatcaccat ccacggactg
    16321 aacgcccacg gcgtggcatc aataccgtgt aatacatctg ctaaatcaca ccattgataa
    16381 tccatcactt catcatcgtt gatctgtaac gcactggtgg tgcgtgcggc aaataccgga
    16441 cacacttcat tttccacaat gccattcgga tcggtggcgc gatagtagaa gtcaggatag
    16501 atagattcag gaggcgtaat ttccacgcca agctcataac ggcaacggcg gatcaccgcg
    16561 tcttcgttgc tttctcccag ttgtgggtga ccacaaaccg agttagtcca cacgccaggc
    16621 cacgcttttt tgctaagggc gcggcgggta actaataatt gccctttggc attaaacagc
    16681 caactggaga acgcgagatg taagagagtg tctgccgtgt gtgcggcata cttttccagc
    16741 gtacccgtgg gaactccctg tgcattcaat aaaatgacgt gttccgtttg cataatttct
    16801 cacatgtaat tctaatcact catcattata gataattgaa gagtgaaatg attaaccaag
    16861 tgagcgttta tcgacaaccg cccgttttga gcggatgtcg acaggtaaaa accatttaaa
    16921 aaagcagcat catatatttg aagcgacttt caatggccat tgcaacacag tcagaaatga
    16981 caggaataga gagagtaaaa agcaacagca gactgaatat agcgcgcatt aaaagattca
    17041 tattattctc catgctcatt tttcttcagc ttgcgcatca gaagccacat acgtactgtc
    17101 ctgactttta aatctttatc agagacggat tccttcacca gatcagcatg atgctgatag
    17161 ccattaaaga agacgttcag cacaacggcg ctaagggttg cgagcataat gccgctatgc
    17221 agcaacggtt gcagtacggc cggtaactta gaaaagaaat cgtgagagag cgtcggagtc
    17281 atgccaacgc cgagactgat cgccacaata tagaggttgt aacggttggt ggtgtagtta
    17341 cagcgcgaca gaattcgaat ccctgtcgcc agtaccatgc cgaacatcac cagcccagca
    17401 caaattgcgg aatggaggcg accagcaccg ccatttttgg caccatgcca aacaggatta
    17461 atataattcc cgaagaaata cacacccagc ggctatgaac gcgcgtcacg ctaaccaggc
    17521 caacgttttg tgaaaatgac gtgtggggga agctgttaaa cgttccgcct atcattgtcc
    17581 ctacgccatc gacacgcagc ccgcgaataa tatcgtgtga agagagttta cgaccgacta
    17641 tttcacccag tgccaggaac atccccatcg actcgataaa cacgatgatt aacacggcag
    17701 tcatggtcag aatggaaacg ggatcgaaaa tcggcatacc aaatgacatc ggcgtgacaa
    17761 tcgcaaacca cgaggcatca tgtagcccgg ataaattgac ttcattcatc atccacgaaa
    17821 gtaaaaagcc aaatacaatc cccagtaata cggcgacgtt ggacataaat cctttcgcat
    17881 agcgagtaat gagcaagata aaaattaaga cagcaaagga gatacctaaa taaacgggat
    17941 taccatattg cggattccct ttacctcctg cggcccagtc aatacccacc tgaatgatgc
    18001 taagtccgat agaagtaatc accacaccgg taaccagtgg cgggaataaa ggcatcaagc
    18061 gaccgataag tggcgctaat aatgtggtga taaaacccgc ggcgatagtg gcaccaaata
    18121 tccccagcag gccgatatcc gggttcatcc caatggctat cattggtgtt acagcggcga
    18181 aggtcaccga cataatcacc ggcaggcgga tccccataaa gcggccgata ccgatacatt
    18241 gcaataatgt gacgatcccg cagcaaaaga gatccgagct aatgagcatc gcaatagctt
    18301 ctttggagag gccaagcctg tcgccaatca taagaggaac agcgactgca cctgcgtaca
    18361 tgacaaggac gtgttgcaga ccgagtatga tcagctttcc tggtgataat atgcggtcaa
    18421 cctcatcagt tgggcggtct tgccctgaag atgagggaag ttgggaatct atggcgctca
    18481 tcagtgtttc tcctttcgct cgccagagta aaaagcaacc gtttacgttc atgaaactgt
    18541 ctaaacacat gctcgtggag tgccagtttt tgcgaggaag gggagttaga gacaggaatt
    18601 gcggaggcaa tcacataatc gtggttaaaa cacgaaaatg agaagagaac ctgacaatgg
    18661 aattatctgt aattttctca tattgatatt tcattaatca ttctggcatg tcgcactctc
    18721 gtatttaatc gtttttatct ggttagctct cttttgttcg gcaatgttga aataatgaaa
    18781 gcggcacaga ttgaggggca ataatttgaa ctcagtcgca aaattataat taaatcggtc
    18841 atgctaccta atatatgccc atttattgca tcgcgaaatt tgagaagaca taactcatta
    18901 aatgaaaggg atgcaaatga ataagtttat cgctgctgaa gctgcggaat gtataggctg
    18961 tcatgcttgt gaaattgcct gtgcgatggc acataatcaa gaaaactggc cgctgagtca
    19021 cagtgacttt cgaccacgta tccacgttgt agggaaaggc caggctgcga atccggtggc
    19081 ctgccatcac tgcaacaatg ccccttgcgt tacggcttgt ccggttaatg ctctgacttt
    19141 ccagcccgat agcgtacaac tggacgagca aaaatgtatt ggttgtaaaa gatgcgcaat
    19201 cgcttgcccc tttggcgtcg ttgagatggt cgatacgatt gcgcagaaat gcgacctttg
    19261 taaccagcgc agttccggca cgcaagcctg tattgaagtc tgtccaacac aggcgttacg
    19321 gctgatggac gataaagggt tgcagcagat aaaggtggcc cgccagcgca aaacggcagc
    19381 aggaaaagcg tcatcagacg ctcagccatc tcgcagtgca gcgttgcttc ccattaactc
    19441 gcgtaaaggc gcagataaaa tttcagcgag tgaacggaaa acccactttg gcgaaatcta
    19501 ttgcgggctg gatccacaac aagcgactta tgagagtgac cgctgtgttt attgtgccga
    19561 aaaagctaac tgcaactggc attgcccgct gcataacgct attccggatt acatccgtct
    19621 ggtacaggaa ggaaagatta ttgaagcggc agaactttgc caccagacca gttccttacc
    19681 cgaaatctgc ggcagagttt gcccacagga ccgtctttgt gaaggcgcat gtactttgaa
    19741 agatcactct ggcgcagtct ctatcgggaa tctggaacgc tacatcaccg atactgcgtt
    19801 ggcgatgggc tggcgtcccg atgtcagcat ggtggttccc cgtagcgaaa aagtggcggt
    19861 gattggcgct gggcctgcag gattagggtg tgctgatatc ctggtgcgcg cgggagttca
    19921 ggttgatgtc tttgatcgtc atccagaaat tggcggtatg ctgacttttg gcattcctcc
    19981 tttcaaactc gataaaacag tcttaagcca gcggcgagag atattcaccg caatgggaat
    20041 cgactttcat cttaactgtg aaattggccg cgatattacc tttagcgatt taacttctga
    20101 atatgatgca gttttcatcg gcgtggggac ttacgggatg atgcgagcag atctgccgca
    20161 tgaagatgtg cccggtgtca ttcaggctct accgttcctg acggcccata cccgccagct
    20221 catgggattg ccggagtctg aagagtatcc gctgacggat gtggaaggta agcgagtcgt
    20281 ggtattgggc ggtggcgata cgaccatgga ttgtttgcgg acttccatcc gcctcaatgc
    20341 cgccagcgtg acctgcgcgt atcgtcgtga tgaagtcagt atgccgggct cgcgcaaaga
    20401 ggtggtcaat gcgcgcgagg aaggtgtcga gtttcaattc aatgttcagc cgcaatatat
    20461 cgcttgtgac gaagatgggc gtttaactgc ggtgggcctg attcgtaccg ccatgggtga
    20521 gccggggccg gatggtcgcc gtcgtcctcg tccggtagcg ggttcagagt ttgaattgcc
    20581 cgccgatgtt ctcattatgg cctttggttt ccaggcgcat gccatgccgt ggttgcaggg
    20641 cagcggaatt aaactcgata aatggggcct gattcaaacc ggtgacgtcg ggtatttacc
    20701 tacccagacg catctgaaaa aagtctttgc tggtggtgat gctgttcatg gcgcggatct
    20761 ggttgtcact gcaatggccg caggaaggca ggcggcgcgc gatatgttaa ctctgtttga
    20821 tacgaaggca tcgtgatgaa atcgttaatt atcgttaatc cggctgactg tattggctgc
    20881 cgtacttgtg aagtagcctg tgtggtcgct cacccttcag aacaggagtt gaatgccgat
    20941 gtctttttac cccggctgaa ggtacagcga ctggacagca tcagtgcgcc ggtgatgtgc
    21001 catcagtgtg aaaacgcccc ttgtgttagc gcttgccccg tgggggcgct gacgatgggc
    21061 gagcaggtgg tgcagaccaa ttctgcccgt tgtattggct gtcagagttg cgtgagtgcg
    21121 tgcccgtttg gaatgatcac cattcagtcg ttgccggggg atacccggca acaaatcgtg
    21181 aaatgcgatc tctgtgaaca gcgggaagag gggccagcct gcgttgaatc ttgcccaaca
    21241 caggcgctgc agttgcttac tgaaagagaa ctcaggcgag tccgccagca gcgtattgtt
    21301 gccagcggtg agaatcctct gtgaaagaaa tctccgcgct gaaaggcgcg gagaatctat
    21361 tagattgccc aaccacccgc gtaaaatgcg acaagtgcgg cagtaatgat caccgtacca
    21421 atattcagct tttgccattc gcgtgcaaag acgcggccta cgaccagtgt cacaaagccc
    21481 agcataatac cggtaacgat attacaagtc agaacgatga acacggcaca caccaggcca
    21541 gccatagcgt caataaaatc attgaaatcc agcttcgaga cgttacttaa catcagcaaa
    21601 cctacgtaca tcagagcggg tgcagtggcg taaccaggga tcaaaaatga cagcggtgat
    21661 aagaacagaa tcagcaggaa taacgccccc actacggttg cggttaaccc tgttttaccc
    21721 ccggcggcgg ttcctgccgc tgattcgata taaaccgctg cgggcgctgc gcccaccagg
    21781 ccggagaata ttgaacttac tgagtcactg gtcagggctt taccgccgtt gatgatctgg
    21841 ttgtctttat ctaacaaatt cgcctgaccg gcgacggcac ggatggtacc agtggcgtcg
    21901 aacactgcgg tcatcaccaa tgccagtaca ctcggaagta cagttggctg gagtgccccc
    21961 ataatatcga ggctgaaaat cagcgactta ccatcttcgc cagtcagact gggcatcgcc
    22021 accagaccgt ggtacttcac cgctggatca aagattaagc cgatgatcga gatggcaata
    22081 atcaccaaca agatcccgcc gggtacgcgg cacttttcca gaccgaagat gaccgccagc
    22141 cccagcaagc tcatcatcac cgggaaggag gtaaacgcac cgagcgccac cggcaagcct
    22201 tcaatcgggt ttttgataac cattcccaca ccgttagcag caatcagcag cagaaacagg
    22261 ccgataccga tacctgtacc gtgagctatc cccatcggta aattacgtaa gatccaggta
    22321 cgcacaccgg ttacggaaat ggcggtgaag atgacgccca tcagaaagac cgcgcccagt
    22381 gcgacaggaa cgctaatttg ttgcccgagt accagactga atgcggtaaa cgccgtcagg
    22441 gaaatcgcgc aaccaatcgc cattggcaaa ttggcccata accccatcag caacgagccg
    22501 aagcccgcga ccagacaggt ggcaacaaac acagctgcgg gaggaaaacc tgctttgccc
    22561 agcattcccg gaacgacgat aacggaataa accatggcca gaaaggtcgt taagccagcc
    22621 agtacttcct gacgaacggt actgccacga gcggtaattt taaaataatt atccagcgcg
    22681 ccctgtggct ttggtgcgtc cggtgtttgt aggatgtctc cagacataat gatgtcctca
    22741 cgaggatgtt aaagttttat tattagttgc gttcgtacac cagacgacca tcaacgtagg
    22801 tgcggtagat cgaacggtca tcgcccaacg tcatcatcac gaacaatttg tcgactaaag
    22861 aaacagagtt gtcatagcgc agctgctgta gcggagtggc ggtgggttcc atcaccacga
    22921 aatcagcttc tttgccaggt aaaaagttgc caatcaaatc gtcaaggccc agagatttcg
    22981 ctccgccgag cgtggccagg taaaatgctt catatgccga gaggcgatag ccttgtaatt
    23041 gcaatacctt gtaggcttcg tttagcgttt gcagcatgtt gaaagtggtt ccggcaccga
    23101 tatccgttcc catgcccact ttaactttct tctgccatgc ttttttcaag ttgaataagc
    23161 cgctgccgag gtaaaggttg gaggtcggac agaaagcaat gctggatttg gtttcgctga
    23221 gacgatccca ctctttttct tcgagatgga cgcagtgagc aaagacacag tttttaccgg
    23281 tcagaccgta ctgatggtaa acatccagat aaccatcatg gtcaggataa agcgatttca
    23341 cccaggcaat ttcatctttg ttttcacaga gatgggtatg tacccacgta tccggatatt
    23401 cttctttcag gcgttgcgcc atcgccatct gttcaggaga tgaggtaggg gcgaagcgtg
    23461 gcgtaatcgc atacaacaga cgaccatttt tgtgccagcg ttcgatcagt tctttgcttt
    23521 ggtgatagct gctttcggca gtgtcgagca gataatccgg tgcgttgcgg tccatcatca
    23581 ccttaccggc aatcatacgc atattgatat gactggcggc ttcaaacagc gcatcaacgg
    23641 attgcggatg aacagtgcca aacaccagcg ccgtggtggt tccgttacgt aaaagctgct
    23701 tgatgaagaa tgccgacatt tcgcgggcgt actctaaatc ctcataacga cgttcagtag
    23761 ggaaggtgtg tttattcaac cactccagca attgttcacc ataggccccc accatttcac
    23821 tttgcggata atggatatgt gtatcgacaa agcccggtac tatcagtttg ccgcgatagt
    23881 cgcgcacgcg aatggtgtca ggaatttgat gctttccgtt ttcccattcg ccaaaccatt
    23941 ccacttttcc ctgtttaatg agtaataaac catcctcaat aaaccgcagc gcagaggcaa
    24001 tctcttccgg gttatcgacc gtacgggtga catcaataaa actgcctcgt accgctttta
    24061 acgtgtgttc tcctgacatc attgactcct ttactgttaa tccatctctt ccgctgaggt
    24121 aataccaggc agaacgtttt cctgtcggta
//
LOCUS       DADXDL010000071        23656 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.071, whole genome shotgun sequence.
ACCESSION   DADXDL010000071 DADXDL010000000
VERSION     DADXDL010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23656)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23656)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23656
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.071"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(97..693)
                     /gene="nrfG"
                     /locus_tag="IRB70_003345"
     CDS             complement(97..693)
                     /gene="nrfG"
                     /locus_tag="IRB70_003345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfG"
                     /protein_id="HBC0633220.1"
                     /translation="MKQPQIPVKMLTTLTILMVFLCIGSYLLSPKWQAVRAEYQRQRD
                     PLHQFASQQTPEAQLQALQDKIRANPQNSEQWALLGEYYLWQNDYSNSLLAYRQALQL
                     RGENAELYAALATVLYYQASQHMTAQTRAMIDKALALDSNEITALMLLASDAFMQANY
                     AQAIELWQKVMDLNSPRINRTQLVESINLAKLLQRRSD"
     gene            complement(690..1073)
                     /gene="nrfF"
                     /locus_tag="IRB70_003346"
     CDS             complement(690..1073)
                     /gene="nrfF"
                     /locus_tag="IRB70_003346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase NrfEFG subunit NrfF"
                     /protein_id="HBC0633221.1"
                     /translation="MNKRLLTLLLLFTCFARAQVVDTWQFANPQQQEQALNIASQLRC
                     PQCQNQNLLESNAPVAVSMRHQVYSMVAEGKSEVEIIGWMTERYGDFVRYNPPLTGQT
                     LVLWALPVVLLLLMILILWRVRAKR"
     gene            complement(1066..2784)
                     /locus_tag="IRB70_003347"
     CDS             complement(1066..2784)
                     /locus_tag="IRB70_003347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme lyase CcmF/NrfE family subunit"
                     /protein_id="HBC0633222.1"
                     /translation="MDVFLPEVGFLALLLSLGVNVLTPLTAFAGVRLRWPAMMRLTCI
                     GILAQFALLLLAFGVLTYCFLISDFSVIYVAQHSYSLLSWELKLAAVWGGHEGSLLLW
                     VLLLSAWSALFAWHYRQQTDPLFPLTLAVLSLMLAALLLFVALWSDPFVRIFPPAIEG
                     RDLNPMLQHPGLIFHPPLLYLGYGGLMVAASVALASLLRGEFDGTCARICWRWALPGW
                     GALTAGIILGSWWAYCELGWGGWWFWDPVENASLLPWLSATALLHSLSLTRQRGIFRH
                     WSLLLAIVTLMLSLLGTLIVRSGILVSVHAFALDNVRAVPLFSLFALISLASLALYGW
                     RARDGGPAVRFSGLSREMLILATLLLFCAVLLIVLVGTLYPMIYGLLGWGRLSVGAPY
                     FNRATLPFGLLMLVVIVLATFVSGKRVQLPALLAHAGVLLFAAGIVVSSVSRQEISLN
                     LQPGQQVTLAGYTFRFERLDLQARGNYTSEKAIVALFDHQQRIGELTPERRFYEARRQ
                     QMMEPSIRWNGIHDWYAVMGEKTGPDRYAFRLYVQSGVRWIWGGGLLMIAGALLSGWR
                     GRKRDE"
     gene            complement(2804..3760)
                     /gene="nrfD"
                     /locus_tag="IRB70_003348"
     CDS             complement(2804..3760)
                     /gene="nrfD"
                     /locus_tag="IRB70_003348"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase subunit NrfD"
                     /protein_id="HBC0633223.1"
                     /translation="MTQTSAFHFESLVWDWPIAIYLFLIGISAGLVTLAVLLRRFYPQ
                     AGGADSTLLRTTLIVGPGAVILGLLILVFHLTRPWTFWKLMFHYSFTSVMSMGVMLFQ
                     FYMVVLVLWLAKIFEHDLLALQQRWLPKLGIVQKVLSLLTPVHRGLETLMLVLAVLLG
                     AYTGFLLSALKSYPFLNNPILPVLFLFSGISSGAAVALIAMAICQRKNPHSTEAHFVH
                     RMEIPVVWGEIFLLVAFFVGLALGDDGKVRALVAALGGGFWTWWFWLGVAGLGLIVPM
                     LLKPWVNRSSGIPAVLAACGASLVGVLMLRFFILYAGQLTVA"
     gene            complement(3757..4428)
                     /gene="nrfC"
                     /locus_tag="IRB70_003349"
     CDS             complement(3757..4428)
                     /gene="nrfC"
                     /locus_tag="IRB70_003349"
                     /EC_number="1.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase Fe-S protein"
                     /protein_id="HBC0633224.1"
                     /translation="MTWSRRQFLTGVGVLAAVSGTAGRVVAKTLNINGVRYGMVHDES
                     LCIGCTACMDACREVNKVPEGVSRLTIIRSEPQGEFPDVKYRFFRKSCQHCDHAPCVD
                     VCPTGASFRDAASGIVDVNPDLCVGCQYCIAACPYRVRFIHPVTKTADKCDFCRKTHL
                     QAGKLPACVEACPTKALTFGNLDDPNSEISQLLRQKPTYRYKLALGTKPKLYRVPFKY
                     GEVSQ"
     gene            complement(4425..4991)
                     /gene="nrfB"
                     /locus_tag="IRB70_003350"
     CDS             complement(4425..4991)
                     /gene="nrfB"
                     /locus_tag="IRB70_003350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418495.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c nitrite reductase pentaheme
                     subunit"
                     /protein_id="HBC0633225.1"
                     /translation="MSVLRSLLTAGVLASGLLWSLNGITATPAAQASDDRYEVTQQRN
                     PDAACLDCHKPDTEGMHGKHASVINPNNKLPVTCTNCHGQPSPQHREGVKDVMRFNEP
                     MYKVGEQNSVCMSCHLPEQLQKAFWPHDVHVTKVACASCHSLHPQQDTMQTLSDKGRI
                     KICVDCHSDQRTNPNFNPASVPLLKEQP"
     gene            complement(5036..6472)
                     /gene="nrfA"
                     /locus_tag="IRB70_003351"
     CDS             complement(5036..6472)
                     /gene="nrfA"
                     /locus_tag="IRB70_003351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-forming nitrite reductase cytochrome
                     c552 subunit"
                     /protein_id="HBC0633226.1"
                     /translation="MTRIKINARRIFSLLIPFFFFTSVHAEQTAAPAKPVTVEAKNET
                     FAPQHPDQYLSWKATSEQSERVDALAEDPRLVILWAGYPFSRDYNKPRGHAFAVTDVR
                     ETLRTGAPKNAEDGPLPMACWSCKSPDVARLIQKDGEDGYFHGKWARGGPEIVNNLGC
                     ADCHNTASPEFAKGKPELTLSRPYAARAMEAIGKPFEKAGRFDQQSMVCGQCHVEYYF
                     DGKNKAVKFPWDDGMKVENMEQYYDKIAFSDWTNSLSKTPMLKAQHPEYETWTAGIHG
                     KNNVTCIDCHMPKVQNAEGKLYTDHKIGNPFDNFAQTCANCHTQDKAALQKVVAERKQ
                     SINDLKIKVEDQLVHAHFEAKAALDAGATEAEMKPIQDDIRHAQWRWDLAIASHGIHM
                     HAPEEGLRMLGTAMDKAADARTKLARLLATKGITHEIQIPDISTKEKAQQAIGLNMEQ
                     IKAEKQDFIKTVIPQWEEQARKNGLLSQ"
     gene            6865..8823
                     /gene="acs"
                     /locus_tag="IRB70_003352"
     CDS             6865..8823
                     /gene="acs"
                     /locus_tag="IRB70_003352"
                     /EC_number="6.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate--CoA ligase"
                     /protein_id="HBC0633227.1"
                     /translation="MSQIHKHTIPANIADRCLINPQQYEAMYQQSINAPDTFWGEQGK
                     ILDWIKPYQKVKNTSFAPGNVSIKWYEDGTLNLAANCLDRHLQENGDRTAIIWEGDDA
                     SQSKHISYKELHRDVCRFANTLLELGIKKGDVVAIYMPMVPEAAVAMLACARIGAVHS
                     VIFGGFSPEAVAGRIIDSNSRLVITSDEGVRAGRSIPLKKNVDDALKNPNVTSIEHVV
                     VLKRTGGKIDWQEGRDLWWHDLVEQASDQHQAEEMNAEDPLFILYTSGSTGKPKGVLH
                     TTGGYLVYAALTFKYVFDYHPGDIYWCTADVGWVTGHSYLLYGPLACGATTLMFEGVP
                     NWPTPARMAQVVDKHQVNILYTAPTAIRALMAEGDKAIEGTDRLSLRILGSVGEPINP
                     EAWEWYWKKIGNEKCPVVDTWWQTETGGFMITPLPGATELKAGSATRPFFGVQPALVD
                     NEGHPLEGAAEGSLVITDSWPGQARTLFGDHERFEQTYFSTFKNMYFSGDGARRDEDG
                     YYWITGRVDDVLNVSGHRLGTAEIESALVAHPKIAEAAVVGIPHNIKGQAIYAYVTLN
                     HGEEPSPELYAEVRNWVRKEIGPLATPDVLHWTDSLPKTRSGKIMRRILRKIAAGDTS
                     NLGDTSTLADPGVVEKLLEEKQAIAMPS"
     gene            9036..9350
                     /locus_tag="IRB70_003353"
     CDS             9036..9350
                     /locus_tag="IRB70_003353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF485 domain-containing protein"
                     /protein_id="HBC0633228.1"
                     /translation="MNGTIYQRIEDNAHFRELVEKRQRFATILSIIMLAVYIGFILLI
                     AFAPGWLGTPLNPNTSVTRGIPIGVGVIVISFVLTGIYIWRANGEFDRLNNEVLHEVQ
                     AS"
     gene            9347..10996
                     /gene="actP"
                     /locus_tag="IRB70_003354"
     CDS             9347..10996
                     /gene="actP"
                     /locus_tag="IRB70_003354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation/acetate symporter ActP"
                     /protein_id="HBC0633229.1"
                     /translation="MKRVLTALAATLPFAANAADAISGAVERQPTNWQAIIMFLIFVV
                     FTLGITYWASKRVRSRNDYYTAGGNITGFQNGLAIAGDYMSAASFLGISALVFTSGYD
                     GLIYSLGFLVGWPIILFLIAERLRNLGRYTFADVASYRLKQGPIRILSACGSLVVVAL
                     YLIAQMVGAGKLIELLFGLNYHIAVVLVGVLMMMYVLFGGMLATTWVQIIKAVLLLFG
                     ASFMAFMVMKHVGFSFNNLFSEAMAVHPKGVDIMKPGGLVKDPISALSLGLGLMFGTA
                     GLPHILMRFFTVSDAREARKSVFYATGFMGYFYILTFIIGFGAIMLVGANPEYKDAAG
                     HLIGGNNMAAVHLANAVGGNLFLGFISAVAFATILAVVAGLTLAGASAVSHDLYANVF
                     KKGATEREELRVSKITVLILGVIAIILGVLFENQNIAFMVGLAFAIAASCNFPIILLS
                     MYWSKLTTRGAMLGGWLGLITAVVLMILGPTIWVQILGHEKAIFPYEYPALFSISVAF
                     LGIWFFSATDNSAEGARERELFRAQFIRSQTGFGVEQGRAH"
     gene            complement(11078..12727)
                     /locus_tag="IRB70_003355"
     CDS             complement(11078..12727)
                     /locus_tag="IRB70_003355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter"
                     /protein_id="HBC0633230.1"
                     /translation="MEIFFTILIMTLVVSLSGVVTRVMPFQIPLPLMQIAIGALLAWP
                     TFGLHVEFDPELFLVLFIPPLLFADGWKTPTREFLEHGREIFGLALALVVVTVVGIGF
                     LIYWVVPGIPLIPAFALAAVLSPTDAVALSGIVGEGRIPKKIMGILQGEALMNDASGL
                     VSLKFAVAVAMGTMIFTVGGATVEFMKVAIGGILAGFVVSWLYGRSLRFLSRWGGDEP
                     ATQIVLLFLLPFASYLIAEHIGVSGILAAVAAGMTITRSGVMRRAPLAMRLRANSTWA
                     MLEFVFNGMVFLLLGLQLPGILETSLMAAEIDPNVEIWMLFTDIILIYAALMLVRFGW
                     LWTMKKLSNRFLKKKPMEFGSWTTREILIASFAGVRGAITLAGVLSIPLLLPDGNVFP
                     ARYELVFLAAGVILFSLFVGVVMLPILLQHIEVADHSQQLKEERIARAATAEVAIVAI
                     QKMEERLAADTEENIDNQLLTEVSSRVIGNLRRRADGRNDVESSILEENLERRFRLAA
                     LRSERAELYHLRATREISNETLQKLLHDLDLLEALLIEENQ"
     gene            complement(12878..14227)
                     /gene="ghxP"
                     /locus_tag="IRB70_003356"
                     /gene_synonym="yjcD"
     CDS             complement(12878..14227)
                     /gene="ghxP"
                     /locus_tag="IRB70_003356"
                     /gene_synonym="yjcD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanine/hypoxanthine transporter GhxP"
                     /protein_id="HBC0633231.1"
                     /translation="MSTPSARTGGSLDAWFKISQRGSTVRQEVVAGLTTFLAMVYSVI
                     VVPGMLGKAGFPPAAVFVATCLVAGLGSIVMGLWANLPLAIGCAISLTAFTAFSLVLG
                     QHISVPVALGAVFLMGVLFTVISATGIRSWILRNLPHGVAHGTGIGIGLFLLLIAANG
                     VGLVIKNPLDGLPVALGDFTTFPVMMSLVGLAVIIGLEKLKVPGGILLTIIGISIVGL
                     IFDPNVHFSGVFAMPSLSDENGNSLIGSLDIMGALNPVVLPSVLALVMTAVFDATGTI
                     RAVAGQANLLDKDGQIIDGGKALTTDSMSSVFSGLVGAAPAAVYIESAAGTAAGGKTG
                     LTAITVGVLFLLILFLSPLSYLVPGYATAPALMYVGLLMLSNVAKIDFADFVDAMAGL
                     VTAVFIVLTCNIVTGIMIGFATLVIGRLVSGEWRKLNIGTVVIAVALVTFYAGGWAI"
     gene            complement(14773..15237)
                     /gene="soxR"
                     /locus_tag="IRB70_003357"
     CDS             complement(14773..15237)
                     /gene="soxR"
                     /locus_tag="IRB70_003357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensitive transcriptional activator SoxR"
                     /protein_id="HBC0633232.1"
                     /translation="MEKKLPRIKALLTPGEVAKRSGVAVSALHFYESKGLISSIRNSG
                     NQRRYKRDVLRYVAIIKIAQRIGIPLATIREAFGVLPEGHTLSAKEWKQLSSQWREEL
                     DRRIHTLVALRDELDGCIGCGCLSRSDCPLRNPGDRLGEEGTGARLLEDEQN"
     gene            15323..15646
                     /gene="soxS"
                     /locus_tag="IRB70_003358"
     CDS             15323..15646
                     /gene="soxS"
                     /locus_tag="IRB70_003358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide response transcriptional regulator
                     SoxS"
                     /protein_id="HBC0633233.1"
                     /translation="MSHQKIIQDLIAWIDEHIDQPLNIDVVAKKSGYSKWYLQRMFRT
                     VTHQTLGDYIRQRRLLLAAVELRTTERPIFDIAMDLGYVSQQTFSRVFRRQFDRTPSD
                     YRHRL"
     gene            complement(15649..17235)
                     /gene="pdeC"
                     /locus_tag="IRB70_003359"
     CDS             complement(15649..17235)
                     /gene="pdeC"
                     /locus_tag="IRB70_003359"
                     /EC_number="3.1.4.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="c-di-GMP phosphodiesterase PdeC"
                     /protein_id="HBC0633234.1"
                     /translation="MSHRARHQLLALPGIIFLVLFPIILSLWIAFFWAKSEVNNQLRT
                     FAQLALDKSELVIRQADLVSDAAERYQGQVCTPAHQKRMLNIIRGYLYINELIYARDN
                     HFLCSSLIAPVNGYTIAPADYKREPNVSIYYYRDTPFFSGYKMTYMQRGNYVAVINPL
                     FWSEVMSDDPTLQWGVYDTVTKTFFSLSNEASAATFSPLIHLKDLTVQRNGYLYATVY
                     STKRPIAAIVATSYQRLIAHFYNHLIFALPAGILGSLVLLLLWLRIRQNYLSPKRKLQ
                     RALEKHQLCLYYQPIINIKTEKCIGAEALLRWPGEQGQVMNPAEFIPLAEKEGMIGQV
                     TDYVIDNVFRDLGAYLATHADRYVSINLSASDFHTSRLIARTNQKTEQYAVRPQQIKF
                     EVTEHAFLDVDKMTPIILAFRQAGYEVAIDDFGIGYSNLHNLKSLNVDILKIDKSFVE
                     TLTTHKTSHLIAEHIIELAHSLGLKTIAEGVETEEQVNWLRKRGVRYCQGWFFAKAMP
                     PQVFMQWMEQLPARELTRGQ"
     gene            17665..17946
                     /locus_tag="IRB70_003360"
     CDS             17665..17946
                     /locus_tag="IRB70_003360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjcB family protein"
                     /protein_id="HBC0633235.1"
                     /translation="MATLTTGVVLLRWQLLSAVMMFLASTLNIRFRRSDYVGLAVISS
                     GLGVVSACWFAMGLLGITMADITAIWHNIESVMIEEMNQTPPQWPMILT"
     gene            complement(18045..18581)
                     /gene="ssb1"
                     /locus_tag="IRB70_003361"
     CDS             complement(18045..18581)
                     /gene="ssb1"
                     /locus_tag="IRB70_003361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein SSB1"
                     /protein_id="HBC0633236.1"
                     /translation="MASRGVNKVILVGNLGQDPEVRYMPNGGAVANITLATSESWRDK
                     ATGEMKEQTEWHRVVLFGKLAEVASEYLRKGSQVYIEGQLRTRKWTDQSGQDRYTTEV
                     VVNVGGTMQMLGGRQGGGAPAGGNIGGGQPQGGWGQPQQPQGGNQFSGGAQSRPQQSA
                     PAAPSNEPPMDFDDDIPF"
     gene            18836..21658
                     /gene="uvrA"
                     /locus_tag="IRB70_003362"
     CDS             18836..21658
                     /gene="uvrA"
                     /locus_tag="IRB70_003362"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBC0633237.1"
                     /translation="MDKIEVRGARTHNLKNINLVIPRDKLIVVTGLSGSGKSSLAFDT
                     LYAEGQRRYVESLSAYARQFLSLMEKPDVDHIEGLSPAISIEQKSTSHNPRSTVGTIT
                     EIHDYLRLLFARVGEPRCPDHDVPLAAQTVSQMVDNVLSQPEGKRLMLLAPIIKERKG
                     EHTKTLENLASQGYIRARIDGEVCDLSDPPKLELQKKHTIEVVVDRFKVRDDLTQRLA
                     ESFETALELSGGTAVVADMDDPKAEELLFSANFACPICGYSMRELEPRLFSFNNPAGA
                     CPTCDGLGVQQYFDPDRVIQNPELSLAGGAIRGWDRRNFYYFQMLKSLADHYKFDVEA
                     PWGSLSANVHKVVLYGSGKENIEFKYMNDRGDTSIRRHPFEGVLHNMERRYKETESSA
                     VREELAKFISNRPCASCEGTRLRREARHVYVENTPLPAISDMSIGHAMEFFNNLKLAG
                     QRAKIAEKILKEIGDRLKFLVNVGLNYLTLSRSAETLSGGEAQRIRLASQIGAGLVGV
                     MYVLDEPSIGLHQRDNERLLGTLIHLRDLGNTVIVVEHDEDAIRAADHVIDIGPGAGV
                     HGGEVVAEGPLEAIMAVPESLTGQYMSGKRKIEVPKKRVPANPEKVLKLTGARGNNLK
                     DVTLTLPVGLFTCITGVSGSGKSTLINDTLFPIAQRQLNGATIAEPAPYRDIQGLEHF
                     DKVIDIDQSPIGRTPRSNPATYTGVFTPVRELFAGVPESRARGYTPGRFSFNVRGGRC
                     EACQGDGVIKVEMHFLPDIYVPCDQCKGKRYNRETLEIKYKGKTIHEVLDMTIEEARE
                     FFDAVPALARKLQTLMDVGLTYIRLGQSATTLSGGEAQRVKLARELSKRGTGQTLYIL
                     DEPTTGLHFADIQQLLDVLHKLRDQGNTIVVIEHNLDVIKTADWIVDLGPEGGSGGGE
                     ILVSGTPETVAECEASHTARFLKPML"
     gene            complement(21693..22049)
                     /locus_tag="IRB70_003363"
     CDS             complement(21693..22049)
                     /locus_tag="IRB70_003363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313066.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBC0633238.1"
                     /translation="MTISELLQYCMAKPGAEQSVHNDWKATQIKVEDVLFAMVKEVEN
                     RPAVSLKTSPELAELLRQQHSDVRPSRHLNKAHWSTVYLDGSLPDSQIYYLVDASYQQ
                     AVNLLPEEKRKLLVQL"
     gene            complement(22053..22469)
                     /locus_tag="IRB70_003364"
     CDS             complement(22053..22469)
                     /locus_tag="IRB70_003364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBC0633239.1"
                     /translation="MWYQKTLTLSAKSRGFHLVTDEILNQLADMPRVNIGLLHLLLQH
                     TSASLTLNENCDPTVRHDMERFFLRTVPDNGNYEHDYEGADDMPSHIKSSMLGTSLVL
                     PVHKGRIQTGTWQGIWLGEHRIHGGSRRIIATLQGE"
     gene            complement(22580..23293)
                     /gene="aphA"
                     /locus_tag="IRB70_003365"
     CDS             complement(22580..23293)
                     /gene="aphA"
                     /locus_tag="IRB70_003365"
                     /EC_number="3.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid phosphatase AphA"
                     /protein_id="HBC0633240.1"
                     /translation="MRKITQAISAVCLLFALNSSAVALASSPSPLNPGTNVARLAEQA
                     PIHWVSVAQIENSLAGRPPMAVGFDIDDTVLFSSPGFWRGKKTFSPESEDYLKNPVFW
                     EKMNNGWDEFSIPKEVARQLIDMHVRRGDAIFFVTGRSPTKTETVSKTLADNFHIPAT
                     NMNPVIFAGDKPGQNTKSQWLQDKNIRIFYGDSDNDITAARDVGARGIRILRASNSTY
                     KPLPQAGAFGEEVIVNSEY"
BASE COUNT         5800 a         6441 c         6022 g         5393 t
ORIGIN      
        1 taatctgcaa taatactgat tggtgattat ttttggcata tgttcattcg attatttttt
       61 atgcagctca ataacataat cttcatcacc agatgattaa tctgatctcc gctgcaacag
      121 tttcgccaaa ttaatcgact cgaccagctg tgtccggttg atccggggtg agttgagatc
      181 catcactttt tgccatagtt cgatggcttg cgcgtaattc gcctgcataa acgcatcgga
      241 agccagcagc atcagagcgg tgatttcgtt agagtccagc gcgagggctt tgtcgatcat
      301 tgcgcgagtc tgggcggtca tatgctggct ggcctggtaa taaagcaccg tcgccagcgc
      361 cgcatacagt tcagcgttct caccacgtag ttgcaacgcc tgacggtacg ccagcagcga
      421 attgctgtaa tcgttttgcc acagataata ctcgcccagt aacgcccatt gttcgctgtt
      481 ttgtggatta gcgcggattt tatcctgcaa tgcctgaagc tgcgcttccg gggtttgctg
      541 gctggcaaac tgatgtagcg gatcgcgctg acgttgatac tccgcacgta ccgcctgcca
      601 ttttgggctt aacagataac tgccgataca gagaaatacc atcaatatcg tgagtgttgt
      661 cagcattttc accggtattt gaggctgttt catcgcttcg cccttacccg ccagaggatc
      721 agtatcatca gcagtaacaa caccactggc agcgcccaca acaccagcgt ctgacccgtt
      781 aacggtgggt tatagcgaac aaaatctccg tagcgttctg tcatccagcc aatgatttcg
      841 acttcacttt tcccctccgc caccatgctg taaacctgat ggcgcatact gactgccacc
      901 ggcgcattag attccagtaa gttctgattc tggcactgcg ggcagcgtaa ctggctggca
      961 atatttaacg cctgttcctg ttgttgcgga ttggcgaatt gccaggtgtc tacaacctga
     1021 gcgcgcgcaa aacaggtaaa taacagcagt agcgtgagaa gccttttatt catcgcgctt
     1081 cctcccccgc catccgctta acaatgcgcc cgcaatcatc aacaatcctc ccccccagat
     1141 ccagcgcaca ccgctttgta catacaaacg aaaagcgtaa cgatccggtc cggttttctc
     1201 gcccatgacc gcataccagt catggatgcc gttccagcga attgacggtt ccatcatttg
     1261 ctgacgacgt gcttcgtaaa aacgccgctc cggcgtcagt tcaccaatgc gttgctgatg
     1321 gtcaaacagc gccactatcg ctttttcgct ggtgtaattg cctctggctt gcagatcgag
     1381 gcgctcaaaa cggaaggtgt atcctgccag cgtcacctgc tgacccggct gtaaattcag
     1441 gctgatctcc tgacggctga cgctggagac cacgatccct gcggcaaata acagtacgcc
     1501 cgcatgcgcc agcagcgccg gaagctgcac gcgtttgcca gagacaaacg tcgccagcac
     1561 aatcaccacc agcatcaaca gaccaaacgg taacgtcgcg cggttaaaat acggcgcgcc
     1621 aacggagagg cgtccccagc ccagcaggcc gtaaatcatc ggataaagcg ttcccaccag
     1681 cacgatcagt agcactgcgc aaaacagcaa cagcgtagcg aggattaaca tttcccgcga
     1741 taaccccgaa aaacgcactg ccggaccacc gtccctggcc cgccaaccat acaacgccaa
     1801 agacgccaga ctaatcagcg caaacaggct gaacaacggc acggcgcgga cattatccag
     1861 cgcgaacgca tgaaccgaaa ccagaatgcc agaacggaca attaaggtgc ccagcagcga
     1921 cagcatcaga gtaactatcg ccagtaacag cgaccagtgg cggaaaatcc cccgctggcg
     1981 tgtcagggac aaactgtgca gcagcgcagt ggcagaaagc cagggtaata aagaggcgtt
     2041 ttccaccgga tcccagaacc accagccgcc ccagcccagt tcgcaatagg cccaccagga
     2101 accgaggatg atccccgccg ttaatgcccc ccagcctggt agtgcccagc gccagcaaat
     2161 tcgggcgcag gtaccatcaa actcgccgcg cagtaaactc gccagcgcca cgctcgccgc
     2221 caccatcaaa ccgccgtagc cgagataaag cagcggtgga tgaaagataa gaccgggatg
     2281 ttgcagcatc ggattgagat cgcggccttc gattgctggc ggaaatatcc gcacgaaggg
     2341 atcggaccac agcgctacaa acagtagcag tgcggcgagc atgagagata aaacggctag
     2401 cgtcagcgga aatagcggat cggtttgctg ccgataatgc caggcaaaca gcgcgctcca
     2461 ggcggaaagc agcagcaccc aaagcagcag cgaaccttca tgaccgcccc acaccgccgc
     2521 cagtttgagt tcccacgaca gcaggctgta gctatgttgg gcgacataaa tgaccgagaa
     2581 atcgctgatg agaaaacaat acgtcagtac gccaaaggcg agcagcagga gcgcgaactg
     2641 cgccagaatg ccgatgcaag tgagtcgcat catggcaggc cagcgcaacc gcactcccgc
     2701 aaaggccgtc aacggggtca acacgttgac cccgagactt aacaacaacg ccagaaaacc
     2761 gacttcagga aggaatacgt ccagaaacca cctctgttct ggcttacgcc accgttaact
     2821 gcccggcgta gagaatgaaa aagcgcagca tcaacacacc gaccaggctg gccccacacg
     2881 ccgccagcac ggcaggaatg ccggaactgc gattgaccca cggtttgagc aacattggca
     2941 caatcaaccc cagcccggcg acaccaagcc agaaccacca cgtccagaaa ccgccgccca
     3001 atgccgccac cagcgcacgc actttaccgt catcgcccag cgccagaccg acaaaaaacg
     3061 ccaccagcag gaaaatttct ccccatacca cagggatctc catacggtgt acaaagtgcg
     3121 cttccgtgga atgcggattt ttgcgctgac atatcgccat ggcgatcagc gccaccgccg
     3181 caccggacga gatgccggag aagaggaaca gcaccggcag gatcgggtta ttgaggaacg
     3241 gatacgattt cagcgccgac agcagaaagc cggtataagc ccccaacaac accgccagca
     3301 ccagcatcaa tgtttccagt ccgcgatgaa cgggcgtcag caggctcaga accttttgca
     3361 cgatccccag cttcggcaac cagcgttgtt gcagggcaag caaatcatgt tcaaagattt
     3421 tcgccagcca cagcaccagc accaccatgt aaaactgaaa cagcatcacc cccatcgaca
     3481 tcaccgaggt aaaactgtag tggaacatca gcttccagaa ggtccacggt cttgtcaggt
     3541 ggaagacgag gatcaacaga ccaaggatca ccgcgccagg cccgacaatc agcgtggtgc
     3601 gcaacaacgt actgtctgca ccgcccgcct gcgggtagaa gcgacgtaac agcacggcca
     3661 gtgtcaccag accggcagaa ataccaatca aaaacaggta gatggcaatc ggccagtccc
     3721 acaccagcga ttcaaaatga aatgcggaag tctgcgtcat tggctcacct ccccgtattt
     3781 aaacggtacg cggtacagct tcggtttggt tcccagcgcc agcttgtagc ggtaagtggg
     3841 cttctggcgc agcagttgcg aaatctcact gttgggatcg tccagattgc caaacgtcag
     3901 cgccttcgtc gggcaagcct caacgcacgc gggtagctta ccggcctgca aatgggtctt
     3961 gcggcagaaa tcgcatttgt ccgctgtctt cgtgaccgga tggataaagc gcacgcggta
     4021 cggacaggcg gcgatgcagt actgacaacc gacgcagaga tcaggattaa catcgacaat
     4081 cccgctggca gcgtcacgaa aagacgcacc ggtcgggcag acgtcaacgc acggcgcatg
     4141 atcgcagtgc tggcaagact tacggaagaa gcgatatttc acatcaggaa attcgccctg
     4201 tggctcgcta cgaataattg tcaggcgcga gacgccttcc ggcaccttgt tcacttcccg
     4261 acaagcatcc atacaggcgg tacagccgat gcataacgac tcgtcatgca ccatgccgta
     4321 acgcacccca ttgatattca acgttttcgc caccacgcgc cctgcggtgc cgctgacggc
     4381 ggccagcacg ccgacgccgg tgagaaactg gcgacgagac caggtcatgg ctgctcctta
     4441 agcaacggaa cagacgccgg gttaaagttc ggattggtgc gctgatcgct gtggcaatcg
     4501 acgcaaatct taatccgtcc tttgtcactt aacgtctgca tcgtatcttg ctgtggatgc
     4561 agggaatggc agctggcgca cgccactttg gttacgtgga catcgtgtgg ccagaacgct
     4621 ttttgcaact gttccggcaa atggcaggac atacagacgc tgttctgctc tccaaccttg
     4681 tacatcggct cgttaaagcg catcacatct ttcacccctt cgcggtgttg cggtgatggc
     4741 tggccgtgac agttggtgca ggtgaccggc agtttgttat tcgggttgat aacggaagca
     4801 tgtttgccat gcataccttc ggtatctggt ttatgacagt ccagacaggc ggcatccggg
     4861 ttacgctgct gggtaacttc gtagcgatca tcagatgcct gcgccgcagg ggtagcggta
     4921 attccgttca ggctccacaa caggcccgac gccagcaccc cggcagttaa taacgaacgt
     4981 aatacgctca tattcactcc attgtgtttt ccgccccttg cgaggcggaa cggggttatt
     5041 ggcttaacag accgttttta cgtgcctgct cttcccactg cgggatcacc gttttgatga
     5101 agtcctgctt ctcggccttg atttgttcca tgttcaggcc aatggcctgc tgggctttct
     5161 ctttggtcga gatatccggg atctggattt catgggtgat gcctttggtc gccagcagtc
     5221 gcgccagttt agtgcgcgca tccgccgctt tatccatcgc cgtaccgagc atcctcagac
     5281 cttcttccgg tgcgtgcata tgaatgccgt gggaagcgat cgccagatcc caacgccact
     5341 gggcatgacg gatatcgtcc tgaatcggct tcatttcggc ttccgtcgcg cctgcatcca
     5401 gcgccgcttt cgcttcgaag tgagcgtgaa ccagttgatc ttcaaccttg attttcaggt
     5461 cgttaatcga ctgcttacgt tccgcgacca ctttttgcaa ggcagctttg tcctgggtat
     5521 ggcagttcgc acaagtctgg gcgaagttat caaacggatt accaatttta tggtcggtgt
     5581 agagtttgcc ttcggcgttc tgcacttttg gcatatggca atcgatacag gtcacgttat
     5641 ttttgccatg aatgcccgct gtccaggttt catattccgg gtgctgcgct ttcagcattg
     5701 gcgttttcga cagggagtta gtccagtcag agaaggcaat tttgtcgtaa tactgctcca
     5761 tattttcgac tttcatgccg tcatcccacg ggaatttaac cgctttgttt ttgccgtcga
     5821 agtaatactc cacatggcac tgaccgcaaa ccatcgattg ctggtcgaaa cgtccggctt
     5881 tctcaaaagg tttaccaatg gcttccatcg cgcgagccgc atacggacgg gaaagggtta
     5941 actccggttt gcctttggcg aactctggtg aggcggtgtt atggcaatcg gcacaaccta
     6001 agttgttgac gatttccggg ccgccgcgcg cccattttcc gtggaagtag ccatcttcgc
     6061 cgtctttctg gatcagacgc gccacatccg ggcttttaca actccagcat gccatcggta
     6121 gcggaccatc ttcagcgttt ttcggcgcac cggtacgcag ggtttcacgc acatcggtca
     6181 cagcaaaggc atgtccacgc ggcttgttgt aatcgcgcga gaagggatac cccgcccaca
     6241 ggatcaccag ccgtggatct tccgccaggg cgtcaacacg ctctgactgt tccgaggtgg
     6301 ctttccagga gagatattga tcgggatgct gcggggcaaa ggtttcattc ttcgcttcca
     6361 cagttacagg ttttgcggga gctgccgttt gttcagcgtg aacagaagtg aaaaagaaaa
     6421 aaggaatcaa taagctgaag atacggcgtg cgtttatttt tatccttgtc ataggggctt
     6481 catccgaatt gcgccattgt tgcaatggcg gtttttattg tttttcacga cagtaaccgc
     6541 acctacactg tcatgacatt gctcgcccct atgtgtaaca aataaccaca ctgtgaatgt
     6601 tgtctttaat caattgtaag tgcatgtaaa ataccacttt agagttagtc agtatcttcc
     6661 tctttttcaa cagcatgcat aactgcatgt tcctcaaaga attaatcaac ttttgttgct
     6721 gaccttcaaa aattaccctg ccgtttattt gcacaattct acttttgcgt gatctgtcgc
     6781 ccaaatacta aacaaaactg ccaatacccc tacatttaac gcttatgcca catattatta
     6841 acatcctaca aggagaacaa aagcatgagt caaattcaca aacacaccat tcctgccaac
     6901 atcgcagacc gttgcctgat aaaccctcag cagtacgagg cgatgtatca acaatctatt
     6961 aacgcaccag ataccttctg gggcgaacag ggaaaaattc tcgactggat caaaccttac
     7021 cagaaggtga aaaacacctc ctttgccccc ggtaatgtgt ccattaaatg gtacgaggac
     7081 ggcacgctga atctggcggc gaactgcctt gaccgccatc tgcaagaaaa cggcgatcgc
     7141 accgccatca tctgggaagg cgacgacgcc agccagagca aacatatcag ctataaagag
     7201 ctgcatcgcg acgtttgccg ctttgccaat accctgctcg agctgggcat taaaaaaggt
     7261 gatgtagtgg cgatttatat gccaatggtg ccggaagctg cggtcgcaat gctggcctgc
     7321 gcccgcattg gcgcggtgca ttcggtgatt ttcggcggct tctcgccgga agccgttgcc
     7381 ggacgcatta tcgattctaa ctcacgactg gtgatcactt ccgacgaagg cgtgcgtgcc
     7441 gggcgtagta ttccgctgaa gaaaaacgtt gatgacgcgc tgaaaaaccc gaacgtcacc
     7501 agcattgaac atgtggtggt actgaaacgt actggcggga aaattgactg gcaggaaggg
     7561 cgcgacctct ggtggcacga cctggttgag caagccagcg atcagcacca ggcggaagag
     7621 atgaacgccg aagatccgct gtttattctc tatacctccg gttctaccgg taagccgaaa
     7681 ggcgtactgc acactaccgg cggttatctg gtttacgcgg cgctgacctt taaatatgtc
     7741 tttgattatc atccgggcga tatctactgg tgcaccgccg atgtgggctg ggttaccgga
     7801 cacagttatt tgctgtatgg cccgctggcc tgcggcgcga ccacactgat gtttgaaggc
     7861 gtaccgaact ggccgacgcc tgcccgtatg gcccaggtgg tggacaagca tcaggtcaat
     7921 attctctata ccgcgcccac ggcgatccgc gcgctgatgg cagaaggcga taaagcgatc
     7981 gaaggcactg accgtttgtc gctgcgcatt ctcggttccg taggcgagcc aatcaacccg
     8041 gaagcgtggg agtggtactg gaagaagatc ggcaacgaga aatgcccagt ggtcgatacc
     8101 tggtggcaga ccgaaactgg cggtttcatg atcaccccac tgcctggcgc taccgagctg
     8161 aaagccggtt cggcaacacg tccgttcttc ggcgtacaac cggcgctggt cgataacgaa
     8221 ggtcatccgc tggagggggc cgccgaaggc agtctggtga tcaccgactc ctggcctggt
     8281 caggcgcgta cattgtttgg cgatcacgaa cgctttgaac agacctactt ctccaccttc
     8341 aaaaatatgt atttcagcgg cgacggcgcg cgtcgcgatg aagatggcta ttactggatc
     8401 accgggcgcg tggacgacgt gctgaacgtc tctggtcacc gtctggggac ggcggagatt
     8461 gagtcggcgc tggtggccca tccgaagatt gccgaagccg ctgtcgtcgg tattccgcac
     8521 aatattaaag gtcaggcgat ctacgcctac gtcacgctta atcacgggga ggaaccgtca
     8581 ccagaactgt acgcagaagt ccgcaactgg gtgcgtaaag agattggccc gctggcgacg
     8641 ccagacgtgc tgcactggac cgactccctg cctaaaaccc gctccggcaa aattatgcgc
     8701 cgtattctgc gcaaaattgc ggcgggcgat accagcaacc tgggcgatac ctcgacgctt
     8761 gccgatcctg gcgtggtcga gaagctgctt gaagagaagc aggctatcgc gatgccctcg
     8821 taactctcaa ttgccggatg cgatccgggc aacaagtcgg aaacgatttg taggcctgat
     8881 aagacgcgac agcgtcgcat caggcattga ttgccggatg cggcgtataa cgccttatcc
     8941 agcctacatt cggcgagggt tacctgggcg ttaacccgct cccataaggg cgcgggaatt
     9001 aaaacaatcc ctacattacc tctggagaat ctgtgatgaa tggcactatt tatcagcgga
     9061 tagaagacaa tgcgcatttc agggagttag tcgaaaaacg gcaacggttt gccaccatcc
     9121 tgtcgattat tatgctggca gtttatatcg gctttatttt actgatcgcc ttcgcgcccg
     9181 gctggctggg caccccgctg aatccgaaca ctagcgtcac acgcggtatt ccgattggtg
     9241 ttggagtaat tgtgatctcc tttgttctca ctggtatcta catctggcgg gcgaacggcg
     9301 aattcgaccg tcttaataat gaagtcctgc atgaggtaca agcatcatga aaagagttct
     9361 gacggcgctt gccgccacac tccctttcgc agctaacgcc gcggatgcta ttagcggggc
     9421 cgtagagcgc cagccaacaa actggcaggc gattattatg ttcctgattt tcgtcgtgtt
     9481 tacgctcggc attacctact gggcgtcaaa acgcgtacgt tcgcgtaatg actactacac
     9541 ggcaggcggc aatatcaccg gttttcagaa cgggctggcg attgccgggg actatatgtc
     9601 cgccgcctca ttcttgggga tctccgcgct ggtgtttacc tccggctatg acgggctgat
     9661 ctactcgttg ggcttcctgg tgggctggcc aatcattctg ttcctgattg ccgaacgtct
     9721 gcgtaacctg ggccgctaca cctttgccga tgtagcctct taccgcctga aacaagggcc
     9781 gattcgtatt ctttcggcct gtggttctct ggtggtggtg gcgctttacc ttatcgccca
     9841 gatggtgggc gcaggtaaac tgatcgagct gttgtttggt cttaactatc acattgcggt
     9901 ggtgctggtc ggcgtgctga tgatgatgta cgtcctgttc ggcggcatgc tggcgaccac
     9961 ctgggtacag attatcaaag ccgttctgtt gctgttcggt gccagcttta tggcctttat
    10021 ggtgatgaaa cacgtcggct ttagcttcaa caatctgttc agcgaagcga tggcggtaca
    10081 cccgaaaggt gtcgacatca tgaagccggg cgggctggtg aaagatccta tctccgcgct
    10141 ctctttgggg ctaggactga tgtttggtac ggctggcttg ccgcatattc tgatgcgctt
    10201 ctttacggtc agcgatgccc gcgaagcacg taagagcgtg ttctacgcca ccggatttat
    10261 gggctacttc tacatcctga cctttattat cggcttcggc gcaatcatgc tggttggtgc
    10321 gaatccggaa tataaagacg cggcgggcca tctgattggt ggtaacaaca tggcagcagt
    10381 tcacctggcg aatgcagtgg gtggcaacct gttcctcggc tttatttcag cggttgcttt
    10441 cgccaccatt cttgcggtgg ttgcgggtct gacgctggcg ggcgcatcgg cggtgtctca
    10501 cgacctgtac gctaacgtct tcaaaaaagg tgcgaccgaa cgtgaagagc tgcgggtatc
    10561 gaaaatcacc gtactgatcc tcggtgtgat tgccattatc ctcggcgtgc tgtttgagaa
    10621 tcagaacatc gcctttatgg tggggctggc gtttgccatc gcggcgagct gtaacttccc
    10681 gatcattctg ctttccatgt actggtcgaa actgactacc cgtggcgcga tgctgggcgg
    10741 ctggttagga ctgattactg cggtggtgct gatgatcctc ggcccgacga tttgggtaca
    10801 gatcctcggt cacgaaaaag ccatcttccc gtatgaatac ccggcgctgt tctctatcag
    10861 cgtggcattc ctcggcatct ggttcttctc ggcaaccgat aactcagcgg aaggcgcgcg
    10921 tgagcgtgaa ctgttccgtg cgcagtttat ccgttcccag accggctttg gcgttgagca
    10981 aggccgcgcg cattaatctc cactagcctc tggtcacctg accaacggta aaaaggtgcg
    11041 atgtactgca cctttttacc gattacaccg ccaagcgtta ttggttctct tcaatcagca
    11101 acgcttcaag caaatcgaga tcgtgcaata atttttgcag cgtttcgtta ctgatctccc
    11161 gcgtggcgcg caggtggtac agttcagcac gttcagaacg caatgccgcc agacggaagc
    11221 gacgctccag gttctcttcc aggattgaac tttctacatc attacgtcca tcggcgcgac
    11281 gacgcaggtt accaatgacg cgagaactaa cctctgtgag cagctggtta tcgatattct
    11341 cttcggtatc cgccgccaga cgctcctcca ttttctggat cgccacaatc gccacttctg
    11401 ccgttgccgc tcgcgcaata cgttcctctt tcaattgttg cgaatggtcc gcgacttcaa
    11461 tgtgttgtag cagaataggc aacatcacca cgccgacaaa cagcgagaag agaatgacac
    11521 cagccgccag gaacaccagc tcatagcgcg ccgggaagac gttaccatcc ggcaagagca
    11581 gcgggataga gagcacaccg gccagagtga tcgccccacg caccccggcg aaagacgcga
    11641 tcaggatttc tcgtgtagtc cacgaaccaa actccatcgg cttcttcttc aggaagcggt
    11701 tgctgagctt tttcatcgtc cacagccagc cgaaacggac cagcatcagc gccgcataaa
    11761 tcagaatgat atcggtaaac agcatccaga tttcgacgtt agggtcgatt tctgccgcca
    11821 tcagcgacgt ctccagaata cccggcagct gcagacctaa cagcaggaat accatgccgt
    11881 taaagacaaa ttccagcatc gcccaggtgc tgtttgcgcg caggcgcatt gccagcggcg
    11941 cacggcgcat cacaccggaa cgggtgatgg tcatcccggc ggcaaccgca gcgaggatac
    12001 cggaaacgcc aatatgttcg gcaatcagat aagaagcgaa tggcagcagg aacagcagaa
    12061 caatctgcgt cgcgggttca tcaccgcccc agcggctgag gaatcgcagc gagcgaccat
    12121 acagccagct caccacaaaa ccggcgagaa taccgcctat tgccactttc ataaattcga
    12181 ccgtcgcacc gccgacggtg aagatcatcg tccccatcgc cactgctacg gcaaacttca
    12241 acgacaccag gccagaggcg tcattcatca acgcttcgcc ctgcaaaatg cccatgattt
    12301 ttttcgggat gcgcccttcg ccaacaatcc cggagagcgc cacagcatcg gtcggagaaa
    12361 gcaccgccgc cagcgcaaag gcggggatca gcggaatgcc cggcaccacc cagtaaataa
    12421 ggaagccaat gccgaccacg gtgaccacca ccagcgccag cgcgaggccg aaaatctctc
    12481 gaccatgttc gagaaattca cgggtcggcg ttttccagcc atcagcgaac agcaacggcg
    12541 ggataaacaa gactaaaaag agttcaggat caaactccac atgcaaacca aacgtcggcc
    12601 acgccagtag cgcaccgatg gcgatttgca taagcggaag cgggatctga aagggcatga
    12661 cacgagtgac caccccggac agcgagacca cgagggtcat tatcagtatg gtgaagaaga
    12721 tttccatgcg ttccctgttt gcgatgtttt ttatgatctg agaaaggcgt tatgcctgaa
    12781 ttctcatttt ttcagaatat cgcaaaagct cacacaatgt gcggagaaaa taaaaacggg
    12841 cagccattgc cacccgtttt cagaatccta tgtaagatta gatagcccag ccacccgcat
    12901 agaaggtcac cagcgccacg gcaataacga ccgtaccgat gttcaacttg cgccattcgc
    12961 cggaaaccag acgaccaatc accagagtcg cgaagccgat catgatgcct gttacgatgt
    13021 tacaggtcag cacgatgaat accgccgtaa ccagacccgc catcgcatca acaaaatcag
    13081 caaagtcgat tttcgccacg ttgctcagca tcagcaggcc aacgtacatc agcgccggag
    13141 ccgttgcgta ccccggaacg aggtaagaga gcggagagag gaacagaatc agcaggaaca
    13201 gcacgccaac ggtgatagcc gtcaacccgg ttttaccgcc cgccgccgta cccgccgcag
    13261 actcgatgta taccgctgcc ggagctgcac ccaccaggcc agagaaaacg ctgctcatgg
    13321 agtcagtggt cagtgctttc ccgccgtcga tgatctgccc gtctttatcc agcaggttcg
    13381 cctgaccggc gacggcgcgg atagttccgg tggcatcaaa tactgccgtc atcaccagtg
    13441 ccagaacact tggcaggact acaggattca gcgcccccat aatgtccagg ctgccaatca
    13501 gtgaattgcc gttttcatcg ctcaatgaag gcatggcgaa aacgccggag aaatggacgt
    13561 taggatcgaa gatcaaaccg acaattgaga taccgataat ggtcagcaga atgccaccag
    13621 ggactttcag tttttccagg ccaataatca ctgccagccc caccaacgac atcatcaccg
    13681 gaaaggtcgt gaaatccccc agcgcgacgg gcagaccatc aagtgggttt ttaatcacca
    13741 gaccgacacc attagcagca atcagcagca ggaacagacc gataccaatc cccgtgccgt
    13801 gcgccacacc gtgcggcaag ttgcgcaaaa tccagctacg gatacccgtg gcagaaatga
    13861 ccgtaaacag cacacccatc aggaacacgg cacccagcgc gacaggtacg ctaatatgtt
    13921 gccccagcac cagactgaat gcggtaaacg ccgtcaggga gatggcgcaa ccaatcgcca
    13981 acggcagatt agcccacaga cccatcacga tagaaccgag tccggcaacc agacaggtcg
    14041 caacgaaaac tgccgcaggc gggaagcccg ctttacccaa catgcctgga acgacgataa
    14101 ccgagtagac catcgccaga aacgttgtta acccggcaac cacttcctga cggacagtgc
    14161 ttccacgttg tgaaatttta aaccaggcgt cgagtgaacc gccggtacgc gctgatggcg
    14221 tagacataag aaaacatccc ctgagagttt aattttcgtc aagatgcgtg gcggacaatc
    14281 ccctgccagc gaaacgttat cttcctgctc caggtttgcg acaaattggt gcgtcgcaaa
    14341 aaagcaaacg tttagctccg cgcatacaaa acgggtggta aaaaaagcaa acgattatcc
    14401 ggcgatcata gcggcttttt caaccgaagt ttgctgcttt tttctctttt attgtcttga
    14461 cgatgaaaaa ccaggcaatt gatgcgcaaa cgttatcgtc gatgcgcaag attgcagcgt
    14521 tatcgaaccg tataccgttc aggattgcga taaaaaatcg tctgagatga caaaaatatt
    14581 gcggctaaaa agtgtacttt tacactggcg aagaaacgcc ggtgacatac aattaaagca
    14641 tcaacaccaa ccggaacctc caccacgtgc tcgaatgagg tgtgttgacg tcgggggaaa
    14701 ccctcctgtg taccagcggg atagagagaa agacaaagac cggaaaacaa actaaagcgc
    14761 ccttgtggcg ctttagtttt gttcatcttc cagcaagcgt gcgcctgtgc cttcttctcc
    14821 taagcggtcg cccgggttac gcaatgggca atcactgcgc gaaaggcagc cacaaccaat
    14881 acatccgtcc agttcgtcac gcagcgccac taaggtatga atgcgccgat ccaactcttc
    14941 tcgccattgg gacgaaagct gtttccactc tttcgcactt aatgtatgcc cttcgggcaa
    15001 cacgccaaat gcttcacgaa tggtcgccag cggaatgcca atacgctgag caattttgat
    15061 gattgcgaca tatcgcaaca catcacgttt atatcgccgc tgattgccgc tattacggat
    15121 actgctaatc aaccctttgc tttcatagaa atgcagcgcc gataccgcca caccgctgcg
    15181 tttcgccact tcgccggggg ttagcagcgc tttaatgcgg ggtaatttct tttccataaa
    15241 tcgctttacc tcaagttaac ttgaggaatt atactcccca acagatgaat taacgaactg
    15301 aacactgaaa agaggcagat ttatgtccca tcagaaaatt attcaggatc ttatcgcatg
    15361 gattgacgag catattgacc agccgcttaa cattgatgtc gtcgcaaaaa aatcaggcta
    15421 ttcaaagtgg tacctgcaac ggatgttccg cacggtgacg catcagacac ttggtgatta
    15481 cattcgccaa cgccgcctgt tgctggccgc cgttgagttg cgcaccaccg agcgtccgat
    15541 ttttgatatc gcaatggacc tgggttatgt ctcgcagcag accttctccc gcgttttccg
    15601 tcggcagttt gatcgcactc caagcgatta tcgccaccgc ctgtagtttt attgcccgcg
    15661 cgttaactcc cgcgcgggta attgctccat ccattgcata aacacctgcg gcggcatcgc
    15721 cttcgcaaag aaccatccct ggcaatagcg cacgccgcgt ttgcgcagcc agttaacctg
    15781 ttcctcagtt tcgacgcctt cagcgatcgt ttttaacccc agactgtgcg ccagctcgat
    15841 gatgtgttcc gcaatcaaat gactggtttt atgggtggtc agcgtctcaa caaacgattt
    15901 atcgattttc aaaatatcga cattcaatga tttaaggtta tgcaagttag agtagccaat
    15961 accaaaatca tcaattgcca cttcgtaacc agcctggcgg aaagccagaa taattggtgt
    16021 cattttgtcg acatcaagaa atgcatgttc agtcacttca aatttaattt gctgtggacg
    16081 caccgcgtat tgctctgttt tctgattggt tcgcgctatc aaccgtgacg tatgaaaatc
    16141 ggaggccgac aggttaatag aaacatagcg atcggcatgt gttgccaggt atgcgcccag
    16201 atcgcggaag acattatcaa taacataatc agttacctgt ccgatcatcc cctccttttc
    16261 tgccagcgga ataaactctg ccggattcat tacttgcccc tgctcaccag gccaacgtaa
    16321 caatgcttca gccccgatac atttttctgt tttgatattg attattggct ggtaataaag
    16381 gcaaagttga tgtttttcga gggcgcgttg caatttgcgt ttgggagaca aatagttttg
    16441 tcgaatacgt agccagagta atagcagaac aagactcccc aaaataccgg cgggtaacgc
    16501 aaaaataaga tgattataaa aatgcgctat aagacgttga tatgaagtcg caacaatggc
    16561 cgcaattggg cgttttgtcg aataaactgt cgcatataaa tagccatttc tttgtacagt
    16621 taaatccttc aaatgaatca gtggagaaaa cgttgctgcc gaggcctcgt tgcttaacga
    16681 gaaaaaggtt ttcgttaccg tatcatatac accccattgc aatgtcggat catcagacat
    16741 cacttcactc cagaagagag ggttgatgac cgccacataa tttccccgct gcatataggt
    16801 cattttatag ccagagaaaa aaggcgtatc gcggtaataa tagatagaaa cgttaggttc
    16861 acgcttataa tcggccggtg caatcgtata gccgtttaca ggcgctatca gcgatgagca
    16921 taaaaaatgg ttatcacggg catagatcaa ttcattaata taaagatagc cacgaataat
    16981 attcaacatt cgcttttgat gggctggggt gcaaacttgc ccctgatagc gttcagctgc
    17041 atcgctcact aaatctgcct gacgaatgac cagctcagat ttatccaacg ccagctgagc
    17101 aaaggttcgg agctgattat tcacttctga ttttgcccaa aagaaggcaa tccatagcga
    17161 cagaatgatg ggaaagagaa ctaaaaagat aatgcccggc aacgccagta attggtgtcg
    17221 tgcacgatga ctcattgcta tcaatttcct gcctgtttat acccggtcat tgcaaggcga
    17281 gaaccctggt tatcgacgtc tttagataaa tcttacggta taaatagcac ttttgcctga
    17341 tttgaaattg ataccttttt aatcgtcacc tgaataaaaa taattcattg atattcaaaa
    17401 ctaatttcct acaggaatgc agaggcggtg ggaagatata cccttaatgc cgctgaaaaa
    17461 acacataatc tgtacggcaa taaaagtcac ggcctaatct ggctaacaaa caatcaattg
    17521 tgatatagtt cacaaaatta atgaaacaaa cagagtgttt cttttttgtg ttctgcaagc
    17581 cccgcgatag ccagattgta tcacgcctcc cgtgaacaac gccgcgctgt ccgaggcatc
    17641 ggctcttttc agaggaattg tttgatggct accctcacca ctggcgtggt tcttcttcgc
    17701 tggcaacttc ttagtgccgt aatgatgttt ctggccagca cactcaacat ccgttttcgt
    17761 cggtctgatt atgtcgggct tgcagtgatc agcagcggtc tgggcgtggt ttctgcctgc
    17821 tggttcgcaa tggggttgct tggcatcaca atggcggata tcaccgccat ctggcacaac
    17881 atcgagtcgg tgatgataga agagatgaat cagacaccgc cacaatggcc aatgattttg
    17941 acttgatatg tagaagcctc caaaacggag gcttcttttt tatggctggc agatgcttta
    18001 atcatccacc ttaaaacaat ataacctatt gttttaacga caaatcagaa cggaatatcg
    18061 tcatcaaagt ccatcggcgg ctcgttagac ggcgctgccg gagcggactg ctgcgggcga
    18121 gactgcgcgc cgccgctgaa ctgattgcca ccctgcggct gctgaggctg accccaacca
    18181 ccctgcggct gaccaccacc gatattgcca cctgccggag cgccaccacc ctgacgacca
    18241 cccagcatct gcatggtgcc gccaacgttc accacgactt ctgtggtgta gcgatcctga
    18301 ccggattgat cggtccattt gcgggtacgc agctgacctt cgatataaac ctgagaacct
    18361 ttacgcagat attcgctggc tacttctgcc agtttgccga acagcacaac gcggtgccat
    18421 tcagtctgct ctttcatctc gccggtcgct ttgtcacgcc aggattcgga agtagccagc
    18481 gtaatgttgg caactgcgcc accatttggc atgtagcgta cttccgggtc ctgacccaga
    18541 ttaccaacga gaataacctt gtttacgcct ctgctggcca tgttcgtgtc tcctgaaaaa
    18601 aaatcgttct gaataagtgt aaacgcgcga ttgtaccatt accaatagcg cttttactat
    18661 gttgtgacct cggttccggg aaacaaacct ggccagacat tgttacacaa cactccgggt
    18721 aatgcattcc aatactgtat attcattcag gtcaatttgt gtcataatta accgtttgtg
    18781 atcgccggta gcaccatgcc accgggcaaa aaagcgttta atccgggaaa ggtgaatgga
    18841 taagatcgaa gttcggggcg cccgcaccca taatctcaaa aacatcaacc tcgttatccc
    18901 ccgcgacaag ctcattgtcg tgaccgggct ttcgggttct ggcaaatcct cgctcgcttt
    18961 cgacacctta tatgccgaag ggcagcgccg ttacgttgaa tccctttccg cctacgcgcg
    19021 gcagtttctg tcactgatgg aaaagccgga cgtcgatcat attgaggggc tttctcctgc
    19081 catctcaatt gagcagaaat caacgtctca taacccgcgt tctacggtgg ggacaatcac
    19141 cgaaatccac gactatttgc gtttgttgtt cgcccgcgtc ggcgagccgc gctgtccgga
    19201 ccacgacgtc ccgctggcgg cgcaaaccgt cagccagatg gtggataacg tgctgtcaca
    19261 gccggaaggc aagcgtctga tgctgcttgc gccaatcatt aaagagcgca aaggcgaaca
    19321 caccaaaacg ctggagaacc tggcaagcca aggttacatc cgtgctcgta ttgatggcga
    19381 agtctgcgat ctttccgatc cgccgaaact ggaactgcaa aagaaacaca ctattgaagt
    19441 ggtggttgat cgcttcaagg tgcgtgacga tcttacccaa cgtctggccg agtcgtttga
    19501 aaccgcgcta gagctttccg gtggtaccgc ggtagtggcg gatatggacg acccgaaagc
    19561 ggaagagctg ctgttctccg ccaacttcgc ctgcccaatt tgcggttaca gtatgcgcga
    19621 gctggagccg cgactgtttt cgtttaacaa cccggcgggg gcctgcccga cctgcgacgg
    19681 ccttggcgta cagcaatatt tcgatcctga ccgcgtgatc cagaatccgg aactgtcgct
    19741 ggctggcggt gcgatccgtg gctgggatcg ccgcaacttc tattatttcc agatgctgaa
    19801 atcgctggca gatcactata agttcgacgt cgaagcgccg tggggcagcc tgagcgcgaa
    19861 cgtgcataaa gtggtgttgt acggttctgg caaagaaaac attgaattca aatacatgaa
    19921 cgatcgtggc gatacctcca ttcgtcgtca tccgtttgaa ggcgtgctgc acaatatgga
    19981 gcgccgttat aaagagacgg agtccagcgc ggtacgcgaa gaattagcca agttcatcag
    20041 caatcgcccg tgcgccagct gcgaagggac gcgtctgcgt cgggaagcgc gccacgtgta
    20101 tgtcgagaat acgccgctgc ccgccatttc cgacatgagc attggtcatg cgatggaatt
    20161 cttcaacaat ctcaaactcg caggtcagcg ggcgaagatt gcggaaaaaa ttcttaaaga
    20221 gatcggcgat cgtttgaaat tcctcgttaa cgtcggcctg aattacctga cgctttcccg
    20281 ctcggcagaa acgctttctg gcggtgaagc ccagcgtatt cgtctggcga gccagattgg
    20341 tgcgggcctg gttggcgtta tgtacgtgct ggatgagccg tctatcggcc tgcaccagcg
    20401 cgataacgag cgcctgttgg gtacgcttat ccatctgcgc gatctcggta ataccgtgat
    20461 tgtggtggag cacgacgaag acgcgattcg cgcggctgac catgtgatcg atatcggtcc
    20521 tggtgcgggt gttcacggcg gtgaagtggt cgcggaaggt ccactggaag cgattatggc
    20581 ggtgccggag tcgttgaccg gacagtacat gagcggtaaa cgcaagattg aagtgccgaa
    20641 gaaacgcgtt ccggcgaatc cggaaaaagt gctgaagctg acgggtgcac gcggtaataa
    20701 cctgaaagac gtgacgctaa cgctgccagt cggtctgttt acctgcatca caggggtttc
    20761 aggttccggt aaatcgacac tgattaacga cacactgttc ccgattgccc aacgccagtt
    20821 gaatggtgcg accatcgccg aaccggcacc gtatcgcgat attcagggac tggagcattt
    20881 cgataaagtg atcgatatcg accaaagccc aattggtcgt actccgcgtt ctaacccagc
    20941 gacctatacc ggcgtgttta cgcctgtgcg cgaactgttt gcgggcgtac cggaatcccg
    21001 tgcgcgcggc tatacgccgg gacgtttcag ctttaacgtc cgtggcggac gctgcgaagc
    21061 ctgtcagggc gacggcgtga tcaaagtgga gatgcacttc ctgccggaca tttacgtacc
    21121 gtgcgaccag tgtaaaggta aacgctataa ccgtgaaacg ctggaaatta agtacaaagg
    21181 caaaaccatc cacgaagtgc tggatatgac catcgaagag gcgcgtgagt tctttgatgc
    21241 cgtacctgca ctggcgcgta agctgcaaac gttgatggac gttggcctga cgtacattcg
    21301 cctggggcag tccgcaacca ccctttcagg cggtgaagcc cagcgcgtga agctggcgcg
    21361 tgagctgtca aaacgcggca ccgggcagac actgtatatt ctcgacgagc cgaccaccgg
    21421 tctgcacttc gccgatattc agcaactgct cgacgtactg cataaactgc gcgatcaggg
    21481 caataccatt gtggtgattg aacacaatct cgacgtgatc aaaaccgctg actggattgt
    21541 cgacctggga ccggaaggcg gcagtggcgg cggcgagatc ctcgtctccg gaacgccaga
    21601 aaccgtcgcg gagtgcgaag cttcgcatac ggcacgcttc ctcaagccga tgctgtaatc
    21661 gttaaggccg ctttctgagc ggccttttcc tttcagagtt gcaccagcaa tttacgtttt
    21721 tcttccggca gcaaattcac cgcctgctga taagacgcat ccaccagata atagatttgc
    21781 gaatccggca gcgaaccgtc gagatacacg gtgctccagt gcgctttatt cagatggcgg
    21841 cttggacgca catcgctgtg ctgctgacgt agcagctccg ccagctccgg gctggttttc
    21901 agcgaaaccg ccgggcgatt ttctacttct ttcaccatcg caaacagtac atcttccact
    21961 ttgatctgcg tcgctttcca gtcgttatgc acgctctgtt ctgcgcctgg ttttgccatg
    22021 caatattgta gcaactccga aatggtcatt ttttactccc cttgtagtgt cgcgataatg
    22081 cgacgcgatc cgccgtggat gcgatgttcc cccagccaga tgccttgcca ggtgccggtc
    22141 tgaatacgcc ctttatgcac cggcaataca agcgatgttc ccagcattga ggatttgata
    22201 tgagaaggca tatcgtctgc tccctcatag tcatgctcat aatttccgtt gtcgggaacg
    22261 gtgcggagga aaaaacgctc catgtcgtgg cgtacggtgg gatcgcagtt ctcattaagt
    22321 gtcagagagg cggaggtatg ttgcagcaac agatgcagta aaccgatgtt aacgcgcggc
    22381 atatcagcca gctgattcag aatttcatcc gttaccagat gaaacccacg agatttggcg
    22441 ctaagcgtga gcgtcttttg ataccacatg tgctgctcct tgataaaact ctcttaatca
    22501 gtttgcagca agacagagaa aggataaagg tgtgattaaa aaaacagcat tcgggagagt
    22561 gtcacgctct cccgctctgt cagtattctg aattgacgat cacctcttca ccaaacgcac
    22621 ccgcttgtgg caagggtttg taggtagagt tggaggcgcg cagaatgcgg ataccacgag
    22681 cgccgacatc gcgtgcggcg gtaatatcgt tatcggaatc gccataaaaa attcggatat
    22741 ttttatcctg cagccattgc gattttgtat tttgccctgg tttatcaccc gcaaagatca
    22801 ccggattcat gttggtggca ggaatatgaa aattatccgc cagcgttttt gaaaccgttt
    22861 ctgttttcgt cgggctacga ccagtcacaa agaagatcgc gtcaccgcgg cgtacatgca
    22921 tatcaatcag ctggcgagcg acctcttttg gaatgctgaa ttcatcccag ccattgttca
    22981 ttttttccca gaacacagga tttttcagat aatcttcgct ttctggcgag aaggtttttt
    23041 tgccgcgcca gaagcccgga ctggaaaaaa gtaccgtgtc atcgatatca aaccccaccg
    23101 ccattggcgg acgccctgcg aggctatttt caatttgtgc gaccgaaacc caatgaattg
    23161 gtgcctgttc agcaagcctg gcaacgttag taccagggtt aagcggcgaa ggagatgagg
    23221 ccagggcaac agcggaactg tttagagcga acaataagca aacggcactg attgcctgtg
    23281 tgatcttgcg catatttttc cctaaatagt cagtatgttg aaacttttta ttgtgagatt
    23341 tgttgcaaaa accatctgac cataacgcca gcagcagggg aaaggaagga ttatctgcgg
    23401 tttttgtgat gaaaagcagg atgattatat ttaacccagt aaatacgttc ctgtcgtttt
    23461 tttgtaaaaa aatgtttatt cctcaatgaa ggatacatta attttacgtt tattatgatg
    23521 aatcctctgc aaatgagcga aatttgatag aacatttatc tgctgtacga tttaatgaac
    23581 ttaatgatac agcattacaa aaacaatcga agtttataaa gatgatttct ggttgaccag
    23641 aaccctaccc tacaat
//
LOCUS       DADXDL010000072        23190 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.072, whole genome shotgun sequence.
ACCESSION   DADXDL010000072 DADXDL010000000
VERSION     DADXDL010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 23190)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23190)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23190
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.072"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            129..719
                     /locus_tag="IRB70_003366"
     CDS             129..719
                     /locus_tag="IRB70_003366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005115608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBC0633241.1"
                     /translation="MPLFVEVKKYFIILLALAAIAGLGTHAAWSSNGLPRIDNKTLAR
                     LAQQHPVVVLFRHAERCDRSTNQCLSDKTGITVKGTQDARELGNAFSADIPDFDLYSS
                     NTVRTIQSATWFSAGKKLTVDKRFLQCGNEIYSAIKDLQSKAPDKNIVIFTHNHCLTY
                     IAKDKRDATFKPDYLDGLVMHVEKGKVYLDGEFVNH"
     gene            complement(758..1183)
                     /gene="nudI"
                     /locus_tag="IRB70_003367"
     CDS             complement(758..1183)
                     /gene="nudI"
                     /locus_tag="IRB70_003367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphatase NudI"
                     /protein_id="HBC0633242.1"
                     /translation="MRQRTIVCPLIQNDGAYLLCKMADDRGVFPGQWALSGGGVEPGE
                     RIEEALRREIREELGEQLLLTEITPWTFSDDIRTKTYADGRKEEIYMIYLIFDCVSAN
                     REVKINEEFQDYAWVKPEDLVHYDLNVATRKTLRLKGLL"
     gene            1461..2003
                     /locus_tag="IRB70_003368"
     CDS             1461..2003
                     /locus_tag="IRB70_003368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311165.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633243.1"
                     /translation="MKKIALAGLAGMLLVSASVNAMSISGQAGKEYTNIGVGFGTEST
                     GLALSGNWTHNDDDGDVAGVGLGLNLPLGPLMATVGGKGVYTNPNYGDEGYAAAVGGG
                     LQWKIGNSFRLFGEYYYSPDSLSSGIQSYEEANAGARYTIMRPVSIEAGYRYLNLSGK
                     DGNRDNAVADGPYVGVNASF"
     gene            2103..3305
                     /locus_tag="IRB70_003369"
     CDS             2103..3305
                     /locus_tag="IRB70_003369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide deamidase-related
                     protein YfaY"
                     /protein_id="HBC0633244.1"
                     /translation="MLKVEMLSTGDEVLHGQIVDTNAAWLADFFFHQGLPLSRRNTVG
                     DNLDDLVTILRERSQHADVLIVNGGLGPTSDDLSALAAATAKGEGLVLHEAWLKEMER
                     YFHERGRVMAPSNRKQAELPASAEFINNPVGTACGFAVQLNRCLMFFTPGVPSEFKVM
                     VEHEILPRLRERFSLPQPPVCLRLTTFGRSESDLAQSLDTLQLPPGVTMGYRSSMPII
                     ELKLTGPASEQQAMEKLWLDVKRVAGQSVIFEGTEGLPAQISRELQNRQFSLTLSEQF
                     TGGLLALQLSRAGAPLLACEVVPSQEETLAQTAHWMTERRANHFAGLALAVSGFENEH
                     LNFALATPDGTFALRVRFSTTRYSLAIRQEVCAMMALNMLRRWLNGQDIASEHGWIEV
                     VESMTLSV"
     gene            3525..4307
                     /locus_tag="IRB70_003370"
     CDS             3525..4307
                     /locus_tag="IRB70_003370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBC0633245.1"
                     /translation="MLESSKVPALTRAIDILNLIARIGPCSAATIIDTLGIPKSTAYL
                     LLNELRRQRFLSLDHQENFCLWTKLVELSGHALSKMDLRELARPRLTQLMDTTGLLCH
                     LGIIDNGSAYYILKVESSATISVRSHEGKSLSLYRSGIGKCLLAWQPAAVQQSIIEGL
                     IWEQATPTTITHPQQLHEELARIRRQGWSYDNGEDYADVRCVAAPVFNANNELTAAIS
                     VVGTRLQINEEYRDYLAGKAIACARDISRLLGWKSPFDLQAS"
     gene            4322..5527
                     /gene="rhmD"
                     /locus_tag="IRB70_003371"
     CDS             4322..5527
                     /gene="rhmD"
                     /locus_tag="IRB70_003371"
                     /EC_number="4.2.1.90"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311162.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnonate dehydratase"
                     /protein_id="HBC0633246.1"
                     /translation="MTLPKIKQVRAWFTGGATAEKGAGGGDYHDQGANHWIDDHIATP
                     MSKYRDYEQSRQSFGINVLGTLIVEVEAENGQTGFAVSTAGEMGCFIVEKHLNRFIEG
                     KCVSDIKLIHDQMLNATLYYSGSGGLVMNTISCVDLALWDLFGKVVGLPVYKLLGGAV
                     RDEIQFYATGARPDLAKEMGFIGGKMPTHWGPHDGDAGIRKDAAMVADMREKCGEDFW
                     LMLDCWMSQDVNYATKLAHACAPYNLKWIEECLPPQQYEGYRELKRNAPAGMMVTSGE
                     HHGTLQSFRTLSETGIDIMQPDVGWCGGLTTLVEIAAIAKSRGQLVVPHGSSVYSHHA
                     VITFTNTPFSEFLMTSPDCSTMRPQFDPILLNEPVPVNGRIHKSVLDKPGFGVELNRD
                     CNLKRPYSH"
     gene            5584..6873
                     /locus_tag="IRB70_003372"
     CDS             5584..6873
                     /locus_tag="IRB70_003372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416749.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633247.1"
                     /translation="MSTALLDAVVKKNRARLIPFMLALYVLAFLDRSNIGFAKQTYQI
                     DTGLSNEAYALGAGIFFVVYAFLGVPANLLMRKLGARTWIGTTTLLWGFLSAAMAWAD
                     TEAKFLIVRTLLGAAEAGFFPGMIYLTSQWFPQRNRASIMGLFYMGAPLALTLGSPLS
                     GALLEMHGFMGHPGWFWMFVIEGLLAVGAGVFTFFWLDDTPEQARFLSKEEKTLLINQ
                     LASEEQQKVTSRLSDALRNGRVWQLAIIYLTIQVAVYGLIFFLPTQVAALLGTKVGFT
                     ASVVTAIPWVAALFGTWLIPRYSDKTGERRNVAALTLLAAGIGIGLSGLLSPVLAIVA
                     LCVAAIGFIAVQPVFWTMPTQLLSGTALAAGIGFVNLFGAVGGFIAPILRVKAETLFS
                     SDAAGLLTLAAVAVIGSLIIFTLRVNRTVAQTDVAHH"
     gene            6891..7694
                     /gene="yfaU"
                     /locus_tag="IRB70_003373"
     CDS             6891..7694
                     /gene="yfaU"
                     /locus_tag="IRB70_003373"
                     /EC_number="4.1.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxy-L-rhamnonate aldolase"
                     /protein_id="HBC0633248.1"
                     /translation="MNALLSNPFKERLRKGEVQIGLWLSSTTSYMAEIAATSGYDWLL
                     IDGEHAPNTIQDLYHQLQAVAPYASQPVIRPVEASKSLIKQVLDIGAQTLLIPMVDTA
                     DQARQVVSATRYPPYGERGVGASVARAARWGRIENYMAHVNDSLCLLVQVESKTALDN
                     LDEILGVEGIDGVFIGPADLSASLGYPDNAGHPEVQRIIETSIRRIRAAGKAAGFLAV
                     APDMAQQCLAWGANFVAVGVDTMLYSDALDQRLAMFKSGKNGPRVKGSY"
     gene            complement(7735..7932)
                     /locus_tag="IRB70_003374"
                     /pseudo
     CDS             complement(7735..7932)
                     /locus_tag="IRB70_003374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708134.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7933..8868)
                     /locus_tag="IRB70_003375"
     CDS             complement(7933..8868)
                     /locus_tag="IRB70_003375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISNCY family transposase"
                     /protein_id="HBC0633249.1"
                     /translation="MTESTTSSPHDAVFKTFMFTPETARDFLEIHLPEPLRKLCNLQT
                     LRLEPTSFIEKSLRAYYSDVLWSVETSDGDGYIYCVIEHQSSAEKNMAFRLMRYATAA
                     MQRHLDKGYDRVPLVVPLLFYHGETSPYPYSLNWLDEFDDPQLARQLYTEAFPLVDIT
                     IVPDDEIMQHRRIALLELIQKHIRDRDLIGMVDRITTLLVRGFTNDSQLQTLFNYLLQ
                     CGDTSRFTRFIQEIAERSPLQKERLMTIAERLRQEGHQIGWQEGKLEGLQKGKVEGMH
                     EQAIKIALRMLEQGFEREIVLATTQLTDADIPNCY"
     gene            complement(9061..10251)
                     /gene="glpC"
                     /locus_tag="IRB70_003376"
     CDS             complement(9061..10251)
                     /gene="glpC"
                     /locus_tag="IRB70_003376"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit C"
                     /protein_id="HBC0633250.1"
                     /translation="MNDTSFENCIKCTVCTTACPVSRVNPGYPGPKQAGPDGERLRLK
                     DGALYDEALKYCINCKRCEVACPSDVKIGDIIQRARAKYDTTRPSLRNFVLSHTDLMG
                     SVSTPFAPIVNTATSLKPVRQLLDAALKIDHRRTLPKYSFGTFRRWYRSVAAQQAQYK
                     DQVAFFHGCFVNYNHPQLGKDLIKVLNAMGTGVQLLSKEKCCGVPLIANGFTDKARKQ
                     AITNVESIREAVGVKGIPVIATSSTCTFALRDEYPEVLNVDNKGLRDHIELATRWLWR
                     KLDEGKTLPLKPLPLKVVYHTPCHMEKMGWTLYTLELLRKIPGLELTVLDSQCCGIAG
                     TYGFKKENYPTSQAIGAPLFRQIEESGADLVVTDCETCKWQIEMSTSLRCEHPITLLA
                     QALA"
     gene            complement(10248..11507)
                     /gene="glpB"
                     /locus_tag="IRB70_003377"
     CDS             complement(10248..11507)
                     /gene="glpB"
                     /locus_tag="IRB70_003377"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase subunit GlpB"
                     /protein_id="HBC0633251.1"
                     /translation="MRFDTVIMGGGLAGLLCGLQLQKHGLRCAIVTRGQSALHFSSGS
                     LDLLSHLPDGQPVTDIHSGLESLRQQAPAHPYTLLGPQRVLDLACQAQALIAESGAQL
                     QGSVELAHQRVTPLGTLRSTWLSAPEVPVWPLPAKKICVVGISGLMDFQAHLAAASLR
                     ELDLAVETAEIELPELDVLRNNATEFRAVNIARFLDNEENWPLLLDALIPVANTCEMI
                     LMPACFGLADDKLWHWLNEKLPCSLMLLPTLPPSVLGIRLQNQLQRQFVRQGGVWMPG
                     DEVKKVTCKNGVVNEIWTRNHADIPLRPRFAVLASGSFFSGGLVAERNGIREPILGLD
                     VLQTATRGEWYKGDFFAPQPWQQFGVTTDEALRPSQAGQTIENLFAIGSVLGGFDPIA
                     QGCGGGVCAVSALHAAQQIAQRAGGQQ"
     gene            complement(11497..13125)
                     /gene="glpA"
                     /locus_tag="IRB70_003378"
     CDS             complement(11497..13125)
                     /gene="glpA"
                     /locus_tag="IRB70_003378"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic glycerol-3-phosphate dehydrogenase
                     subunit A"
                     /protein_id="HBC0633252.1"
                     /translation="MKTRDSQSSDVIIIGGGATGAGIARDCALRGLRVILVERHDIAT
                     GATGRNHGLLHSGARYAVTDAESARECISENQILKRIARHCVEPTNGLFITLPEDDLS
                     FQATFIRACEEAGISAEAIDPQQARIIEPAVNPALIGAVKVPDGTVDPFRLTAANMLD
                     AKEHGAVILTAHEVTGLIREGATVCGVRVRNHLTGETQALHAPVVVNAAGIWGQHIAE
                     YADLRIRMFPAKGSLLIMDHRINQHVINRCRKPSDADILVPGDTISLIGTTSLRIDYS
                     EIDDNRVTAEEVDILLREGEKLAPVMAKTRILRAYSGVRPLVASDDDPSGRNVSRGIV
                     LLDHAERDGLDGFITITGGKLMTYRLMAEWATDAVCRKLGNTRPCTTADLALPGSQEP
                     AEVTLRKVISLPAPLRGSAVYRHGDRTPAWLSEGRLHRSLVCECEAVTAGEVQYAVEN
                     LNVNSLLDLRRRTRVGMGTCQGELCACRAAGLLQRFNVTTSAQSIEQLSTFLNERWKG
                     VQPIAWGDALRESEFTRWVYQGLCGLEKEQKDAL"
     gene            13398..14756
                     /gene="glpT"
                     /locus_tag="IRB70_003379"
     CDS             13398..14756
                     /gene="glpT"
                     /locus_tag="IRB70_003379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate transporter"
                     /protein_id="HBC0633253.1"
                     /translation="MLSIFKPAPHKARLPAAEIDPTYRRLRWQIFLGIFFGYAAYYLV
                     RKNFALAMPYLVEQGFSRGDLGFALSGISIAYGFSKFIMGSVSDRSNPRVFLPAGLIL
                     AAAVMLFMGFVPWATSSIAVMFVLLFLCGWFQGMGWPPCGRTMVHWWSQKERGGIVSV
                     WNCAHNVGGGIPPLLFLLGMAWFNDWHAALYMPAFCAILVALFAFAMMRDTPQSCGLP
                     PIEEYKNDYPDDYNEKAEQELTAKQIFMQYVLPNKLLWYIAIANVFVYLLRYGILDWS
                     PTYLKEVKHFALDKSSWAYFFYEYAGIPGTLLCGWMSDKVFRGNRGATGVFFMTLVTI
                     ATIVYWMNPAGNPTVDMICMIVIGFLIYGPVMLIGLHALELAPKKAAGTAAGFTGLFG
                     YLGGSVAASAIVGYTVDFFGWDGGFMVMIGGSILAVILLIVVMIGEKRRHQELLQKRN
                     GG"
     gene            14761..15837
                     /gene="glpQ"
                     /locus_tag="IRB70_003380"
     CDS             14761..15837
                     /gene="glpQ"
                     /locus_tag="IRB70_003380"
                     /EC_number="3.1.4.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBC0633254.1"
                     /translation="MKLTLKNLSMAIMMSGMIMGSSAMAADSNEKIVIAHRGASGYLP
                     EHTLPAKAMAYAQGADYLEQDLVMTKDDHLVVLHDHYLDRVTDVADRFPDRARKDGRY
                     YAIDFTLDEIKSLKFTEGFDIENGKKVQTYPGRFPMGKSDFRVHTFEEEIEFVQGLNH
                     STGKNIGIYPEIKAPWFHHQEGKDIAAKTLEVLKKYGYTGKDDKVYLQCFDADELKRI
                     KNELEPKMGMDLNLVQLIAYTDWNETQQKQPDGSWVNYNYDWMFTPGAMKQVAEYADG
                     IGPDYHMLIEETSQPGNIKLTGMVQDAQQNKLVVHPYTVRSDKLPEYTTDVNQLYDAL
                     YNKAGVNGLFTDFPDKAVKFLNKE"
     gene            complement(15857..16756)
                     /locus_tag="IRB70_003381"
     CDS             complement(15857..16756)
                     /locus_tag="IRB70_003381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000176735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0633255.1"
                     /translation="MTLTQINSLLAVLDYGGFTEASKRLFMTQSAVSQAIAALEQELG
                     VNILLRDRRKAIQLTSAGHRIMHHLRAINREVNAVKEIAEQEKQNPQRTLRLGCFPSV
                     CACILPAVIRYFEIHHPNIKIIPFEENSTAIIDSLQNESIDAGFVHFPVSGMYSVPIY
                     QDKFTVVLPPYHALAKNSTITVEELMGEPLIISKGRYELSIMALFKEKNITPQIKYEF
                     NHPDTAISFIRQGLGIALLPELTLKTIADELCSVPLEPTFYRQISLLAKEKPVEGSPL
                     FLLQMCTEQLVESGKFDMRQDGA"
     gene            16908..18098
                     /locus_tag="IRB70_003382"
     CDS             16908..18098
                     /locus_tag="IRB70_003382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633256.1"
                     /translation="MKEKLWTKDFWAITIISFIIFFVFYVLLTLLPIYISDRLHASPD
                     KAGLLVTLFLIAAIVIRPFAGQWVGKYSNKTILGLSSLAFLVVTALYPFCHSIESLLF
                     IRVLHGITFGVITTVKGTISARLIPASRRGEGISFFSLAMGLAMVVGPWIGLNMARWE
                     AFNMAFWLCTGVAAVGIILSLIMTVPPVISHTDGSTPKMGFAAMFDRAALPFAMVTFF
                     MTFSYAGVSAFLALYARELNLMSAASNFLLCYAIFLMICRTFTGNVCDKKGPKYVVYP
                     CLVFFTVGLVVLGYTQGSIMMVVSGALIGIGYGSVTPVFQTQIISSVEPHKIGVANSL
                     FFNAMDAGLALGACVMGMMVAHTGYRMIYLLGALLVVVAGGVYALQMKGKSGVMLVAA
                     KEIH"
     gene            18179..18829
                     /gene="inaA"
                     /locus_tag="IRB70_003383"
     CDS             18179..18829
                     /gene="inaA"
                     /locus_tag="IRB70_003383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide kinase InaA"
                     /protein_id="HBC0633257.1"
                     /translation="MAVSAKHDEFNHWWATEGDWVEEPNYRRNGMSGVQCVERNGKKL
                     YVKRMTHHLFHSVRYPFGRPTIVREVAVIKELERAGVIVPKIVFGEAVKIEGEWRALL
                     VTEDMAGFISIADWYARHAVSPYSDEVRQAMLKAVALAFKKMHSVNRQHGCCYVRHIY
                     VKTEGKAEAGFLDLEKSRRRLRRDKAINHDFRQLEKYLEPIPKADWEQVKAYYYAM"
     gene            complement(18883..19137)
                     /gene="yfaE"
                     /locus_tag="IRB70_003384"
     CDS             complement(18883..19137)
                     /gene="yfaE"
                     /locus_tag="IRB70_003384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-like diferric-tyrosyl radical
                     cofactor maintenance protein YfaE"
                     /protein_id="HBC0633258.1"
                     /translation="MARVTLRITGTQLLCQDEHPSLLAALESHNVAVEYQCREGYCGS
                     CRTRLVAGQVDWIAEPLAFIQPGEILPCCCRAKGDIEIEM"
     gene            complement(19137..20267)
                     /gene="nrdB"
                     /locus_tag="IRB70_003385"
     CDS             complement(19137..20267)
                     /gene="nrdB"
                     /locus_tag="IRB70_003385"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006683700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleotide-diphosphate reductase subunit
                     beta"
                     /protein_id="HBC0633259.1"
                     /translation="MAYTTFSQTKNDQLKEPMFFGQPVNVARYDQQKYDIFEKLIEKQ
                     LSFFWRPEEVDVSRDRIDYQALPEHEKHIFISNLKYQTLLDSIQGRSPNVALLPLISI
                     PELETWVETWAFSETIHSRSYTHIIRNIVNDPSVVFDDIVTNEQIQKRAEGISSYYDE
                     LIEMTSYWHLLGEGTHTVNGKTVTVSLRELKKKLYLCLMSVNALEAIRFYVSFACSFA
                     FAERELMEGNAKIIRLIARDEALHLTGTQHMLNLLRSGADDPEMAEIAEECKQECYDL
                     FVQAAQQEKDWADYLFRDGSMIGLNKDILCQYVEYITNIRMQAVGLDLPFQTRSNPIP
                     WINTWLVSDNVQVAPQEVEVSSYLVGQIDAEVDTDDLSNFQL"
     gene            complement(20413..22698)
                     /gene="nrdA"
                     /locus_tag="IRB70_003386"
     CDS             complement(20413..22698)
                     /gene="nrdA"
                     /locus_tag="IRB70_003386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside-diphosphate reductase subunit
                     alpha"
                     /protein_id="HBC0633260.1"
                     /translation="MNQNLLVTKRDGSTERINLDKIHRVLDWAAEGLHNVSISQVELR
                     SHIQFYDGIKTSDIHETIIKAAADLISRDAPDYQYLAARLAIFHLRKKAYGQFEPPAL
                     YDHVVKMVVMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSYAAVKQLEGKYLVQNR
                     VTGEIYESAQFLYILVAACLFSNYPRETRLQYVKRFYDAVSTFKISLPTPIMSGVRTP
                     TRQFSSCVLIECGDSLDSINATSSAIVKYVSQRAGIGINAGRIRALGSPIRGGEAFHT
                     GCIPFYKHFQTAVKSCSQGGVRGGAATLFYPMWHLEVESLLVLKNNRGVEGNRVRHMD
                     YGVQINKLMYTRLLKGEDITLFSPSDVPGLYDAFFADQEEFERLYTKYEKDDSIRKQR
                     VKAVELFSLMMQERASTGRIYIQNVDHCNTHSPFDPVIAPVRQSNLCLEIALPTKPLN
                     DVNDENGEIALCTLSAFNLGAINSLDELEELAILAVRALDALLDYQDYPIPAAKRGAM
                     GRRTLGIGVINFAYYLAKHGKRYSDGSANNLTHKTFEAIQYYLLKASNELAKEQGACP
                     WFNETTYAKGILPIDTYKKDLDAIANEPLHYDWEALRESIKTHGLRNSTLSALMPSET
                     SSQISNATNGIEPPRGYVSIKASKDGILRQVVPDYEHLHDAYELLWEMPGNDGYLQLV
                     GIMQKFIDQSISANTNYDPSRFPSGKVPMQQLLKDLLTAYKFGVKTLYYQNTRDGAED
                     AQDDLVPSIQDDGCESGACKI"
BASE COUNT         5371 a         5639 c         6198 g         5982 t
ORIGIN      
        1 ggcattttgc cggcatcgca ggatttttaa tattacacca actgctaatt atcgccagaa
       61 atgtcgctca atttcacggt aattgtctgg ttgcgcttgt ctataggtgg agtttacgtg
      121 ttagcttttt gccgctcttc gttgaagtca aaaaatattt catcatttta ctggcgctcg
      181 ctgcaattgc cggactgggt actcatgccg cctggagtag caatggtttg ccacgtatcg
      241 acaataaaac gctggccaga ctggcacagc agcacccggt tgtcgttttg tttcgccatg
      301 ctgaacgttg cgatcgttca accaatcaat gcttgtcaga taaaacaggt attacggtca
      361 aaggtaccca ggatgcccgt gaactgggca acgcttttag tgctgatatc cctgatttcg
      421 atctttattc cagtaatacc gtccggacca ttcagtcggc gacctggttt tcagcgggta
      481 aaaaattgac ggtagataaa cgatttcttc aatgcggtaa tgagatttat agtgcaatta
      541 aggacttaca aagcaaagca cctgataaaa atatcgttat ttttacccat aatcattgcc
      601 tgacatatat tgctaaagat aagcgtgatg cgacatttaa acctgattat ctggatggtt
      661 tagtcatgca tgtggaaaaa ggcaaagttt atctggatgg ggaattcgtt aaccactaaa
      721 ttttcaatct gacagccagt aatggctgtc atcattgtta cagaagacct ttcaaacgta
      781 acgtttttcg ggtggcgaca ttcaaatcat agtgcactag atcttcaggt tttacccacg
      841 cgtagtcctg aaactcttcg tttattttca cttctcggtt ggcagaaacg cagtcaaaaa
      901 tcaggtaaat catataaatc tcttccttgc gaccatctgc atacgtcttg gtgcgaatat
      961 catcgctgaa ggtccacggc gtgatttctg tcaaaagcag ctgttctccc agttcttcgc
     1021 gaatttcgcg gcgtagtgcc tcttcaattc gttcgccagg ctctacgccg ccacccgaaa
     1081 gcgcccattg accggggaaa acgccgcgat cgtcggccat tttacacagc aaataagcac
     1141 catcattttg aatcaaaggg catacaatag tccgttgtcg cacaggggta ttccttataa
     1201 ataaaaagaa accatgagaa tacggtaact cagaaatatg tgaaagtgac agtaatctct
     1261 tttgcgatga taactgtact tattattatt tttgtgtgta tcgataaagt gtgtttattt
     1321 ttgcggcgtt taattattta agaagtattt agttacaata agtgactaga tccctttttt
     1381 cgctcattga atcctctgcg ccaggcagta caatcccgca gctttgggaa ttttgattaa
     1441 ttgcttgtgg gaaaggggat atgaaaaaaa ttgcgctagc aggtctggcc ggaatgctgt
     1501 tggtttctgc atcggtcaat gcaatgagca tcagcggtca ggcgggtaaa gaatacacca
     1561 atattggtgt cggttttggg actgaatcga cgggcctggc gttaagcggt aactggacac
     1621 ataacgacga cgacggtgac gtcgcgggcg tggggctggg gttgaatctg cctctcgggc
     1681 cgttaatggc gaccgttggc ggaaaaggcg tttacaccaa cccgaattac ggcgatgaag
     1741 gttatgccgc agcggtagga ggtggtttgc agtggaaaat tggcaacagt ttccgtctgt
     1801 ttggcgagta ttattactcc ccggattcgc tctccagcgg tattcaaagt tatgaggaag
     1861 cgaatgcggg cgcgcgttac accattatgc gtccagtcag tattgaggcg ggttatcgct
     1921 acctgaatct gtcgggtaaa gacggtaacc gcgacaacgc cgtggctgac ggcccgtatg
     1981 tgggggttaa cgccagtttc tgatcccttc cggcgcggca ttctgccgcg ccattcagtt
     2041 tcttactacg ccttatctcc ctttgcgtta tagtgattcg ataacaaaag caggagataa
     2101 ccatgttaaa agtggaaatg ttatccaccg gggatgaagt gttacacggg caaatcgttg
     2161 acactaacgc tgcctggctg gccgattttt tctttcatca ggggttgcca ttatctcgcc
     2221 gcaatacggt gggggataac cttgatgact tagtcaccat tcttcgcgaa cggagtcagc
     2281 acgccgatgt gctgatcgtt aacggcgggc tggggccgac cagtgatgat ttaagcgcac
     2341 tcgccgctgc gacagcaaaa ggtgaaggcc tggtgttgca tgaagcctgg ctcaaagaga
     2401 tggaacgcta tttccacgaa cgtggacgag taatggcacc gagcaaccgt aaacaagcag
     2461 agctgcctgc cagtgctgaa tttatcaata acccggtagg caccgcctgt ggttttgccg
     2521 tgcagcttaa tcgttgcctg atgttcttta cccctggcgt accgtcagaa tttaaggtga
     2581 tggtcgagca cgaaatcctg ccgcgcttgc gcgagcgttt ttctttaccg cagccgccgg
     2641 tttgtctgcg tttgactacc tttggtcgtt cggaaagcga tctggcacaa agcctggaca
     2701 ctctacaact gccgccgggc gtaacaatgg gctatcgctc ctcaatgccg atcatcgaac
     2761 tgaagctcac cggaccggca agcgagcaac aggcgatgga aaaactgtgg ctggacgtta
     2821 aacgagttgc cggacagagc gtgattttcg aaggcaccga aggactgccc gcgcagatca
     2881 gtcgcgaatt gcaaaaccgc cagttcagcc tgacgttgag cgagcaattc accggcggtt
     2941 tattggcttt gcaactttct cgcgcaggtg ctccattgct ggcgtgtgaa gtggttcctt
     3001 cacaggaaga aaccctggcg caaactgcgc actggatgac agaacggcgg gccaaccatt
     3061 ttgccgggct ggcactggct gtttcgggtt tcgagaacga gcatctcaac tttgcgctag
     3121 ccacgccaga cggcactttc gctctgcgtg tgcgtttcag cactacgcgc tacagcctgg
     3181 ctatccgtca ggaagtgtgc gcaatgatgg cactgaatat gctgcgccgt tggttaaacg
     3241 gccaggacat cgccagtgag catggctgga ttgaggttgt tgagtccatg accttatctg
     3301 tctgattccg ccactctgtg ccggtttact gcaccggcac attccccctc cggcaaaatt
     3361 tgtccaacct gttgtactca ataagaaaaa atccgtgcgc tgattcacaa atttgtgcgt
     3421 aatttctcca gtccgctgga cgaggagcgg gatttgatgc gcttcacaat tttactcccc
     3481 ctgagcaacg agactgattc cagtatctaa gactggagtc cagtatgttg gaatcaagca
     3541 aagttcccgc cctgacacgg gctattgata ttctcaattt gattgcccgc attggcccct
     3601 gtagtgctgc gacgatcatt gacacattgg ggatccctaa aagcacggcc tatttgctgc
     3661 ttaatgaact caggcgtcag cgttttctta gccttgatca ccaggaaaat ttttgtttgt
     3721 ggaccaagct ggtggagctt tccggtcatg cgttaagcaa gatggatctc cgggaactgg
     3781 ctcgaccgcg tttgacgcaa ctgatggata ccaccgggct gttatgccac cttgggatca
     3841 tcgataacgg tagtgcttat tacattctga aagtggagtc ttcagccacc atcagcgtgc
     3901 gttcccatga agggaaaagc ctttcgcttt atcgctccgg catcgggaaa tgccttcttg
     3961 cctggcaacc agccgctgta cagcaaagta ttatcgaagg gctgatctgg gagcaggcga
     4021 cacccacaac gattactcat ccacagcaac ttcacgaaga actggcgcgt attcgccgtc
     4081 agggctggag ctatgacaac ggcgaagatt acgccgatgt ccgttgtgtc gctgcgccgg
     4141 tgtttaacgc caataacgag cttaccgctg cgatctcggt ggtcggtacc cgcttacaaa
     4201 tcaatgaaga ataccgtgat tatctggcgg gcaaggctat tgcctgcgcc agggatattt
     4261 cacgtctgtt gggatggaaa agtccctttg acttacaggc ctcataacaa tggagaacag
     4321 catgacccta ccaaaaatca aacaggttcg cgcctggttt actggcggtg cgacagcaga
     4381 aaaaggcgct ggcggtggtg attatcacga ccagggggcg aatcactgga ttgacgatca
     4441 tattgccacc ccgatgagta aataccgcga ttacgagcag tcacgccagt catttggcat
     4501 taacgttctt ggcacgttga ttgttgaagt cgaagcagaa aacggccaga ccggattcgc
     4561 cgtttcgaca gccggtgaaa tgggctgttt tattgtcgaa aaacacctta accgtttcat
     4621 tgagggtaaa tgtgtcagtg atatcaaact gatccacgat caaatgctca atgccaccct
     4681 gtattactcc ggctctggtg gcctggtgat gaatacgatt tcctgtgtcg atctggctct
     4741 gtgggatctg ttcggcaaag tggtcgggct tccggtttat aaacttttag gcggcgcagt
     4801 tcgtgatgag attcagttct acgccacagg tgcgcgtccg gatctggcaa aagagatggg
     4861 cttcatcggt ggcaaaatgc cgacgcactg ggggccacat gatggcgatg cggggatccg
     4921 caaagatgcc gctatggtcg cggatatgcg tgaaaaatgc ggtgaggatt tctggttaat
     4981 gctcgactgc tggatgagtc aggacgtgaa ctatgccacc aaactggccc acgcttgcgc
     5041 gccctataac ctgaaatgga tcgaagagtg cctgccgcca cagcagtatg aaggttatcg
     5101 cgaactgaaa cgcaacgcac cagcggggat gatggtcacc agcggtgagc accacggcac
     5161 actgcaatct tttcgtacgc tttcagaaac cggtatcgac atcatgcagc cggatgttgg
     5221 ctggtgcggt ggcttaacca cgctggtgga aattgccgca atcgccaaat ccagggggca
     5281 actggtggtg ccgcacggtt cgtctgttta ctcccaccat gcggtgatca ccttcaccaa
     5341 tacgccattc agtgaattcc tgatgaccag cccggattgt tcaacgatgc gtccgcaatt
     5401 tgatccgatt ctgcttaatg agccggttcc ggtgaatggt cgtattcata aatcagtgct
     5461 tgataaaccc ggtttcggcg tcgaactcaa tcgtgactgc aatttgaaac gcccctacag
     5521 ccactaatca ctccgggcgt tgctgtgaca acggtaacgc ccacatattc taaggagctt
     5581 tttatgagca ccgctttgct tgacgccgtg gtgaagaaaa accgcgcgcg tttaattccg
     5641 tttatgttgg cgctgtatgt gctggcgttt ctcgaccgtt cgaatattgg ttttgccaaa
     5701 cagacctacc agattgatac cgggctgagt aatgaagctt atgcgctggg agcaggcatt
     5761 ttctttgtgg tatacgcgtt tctgggggtt ccggcgaatc ttttgatgcg caaactgggg
     5821 gcaagaacct ggattggtac gacaacactg ctgtggggat ttctttcggc tgccatggca
     5881 tgggccgata ctgaagcgaa atttctgatt gttcgcactc tgcttggtgc tgcggaggct
     5941 gggtttttcc ctggtatgat ttatctcacc tcgcaatggt ttccgcagcg taatcgcgcc
     6001 agcattatgg ggctgttcta tatgggcgca ccgctggcgt taacactggg atcaccgctt
     6061 tctggcgcgc tgctggagat gcatggattt atggggcatc ccggctggtt ctggatgttt
     6121 gttattgaag gattgttggc agtcggcgct ggggtattca cattcttttg gcttgatgac
     6181 acaccggagc aggcacgttt tctgagtaaa gaagaaaaaa cgttgcttat caaccaactg
     6241 gcaagtgaag aacaacagaa agtgacttcc cgactgagcg atgcgctgcg taatgggcga
     6301 gtctggcaac tggcgattat ctacctgacc attcaggtag cggtttacgg attaattttc
     6361 ttcctgccga cccaggttgc tgcattgctg gggacaaaag tgggctttac ggcgtcggtg
     6421 gtcaccgcca ttccgtgggt tgcggccttg tttggaacct ggcttattcc gcgctattcc
     6481 gataaaaccg gcgaacggcg taatgtcgca gcgctgacat tactggcggc gggcattggt
     6541 attggtctgt ccgggctgct ttctccagta ctggcgatcg tagcgctgtg tgttgcagcc
     6601 atcgggttta ttgccgtgca gccggtgttc tggacgatgc cgacacaact gctttccggt
     6661 acggcgctgg ctgcggggat tggttttgta aacctgtttg gtgcagtggg cgggtttatt
     6721 gccccgatcc tgcgcgtgaa agcagaaacg ttattttcca gcgatgcggc gggattactg
     6781 acgctggcag cggtggcggt catcggttcg ctgattattt tcactctgcg tgtaaatcgc
     6841 actgttgcgc agaccgacgt ggcacatcat taaataggtt aaggaacacg atgaacgcat
     6901 tattaagcaa tccctttaaa gaacgtttac gcaagggcga agtgcaaatt ggtctgtggt
     6961 taagctcgac tacttcttat atggcagaaa ttgccgccac ctccggttat gactggttgc
     7021 tgattgacgg ggagcacgcg ccaaacacca ttcaggatct ttatcaccag ctacaggcgg
     7081 tagcgcccta tgccagccaa cccgtgatcc gtccggtgga agccagtaag tcgctgatta
     7141 aacaagtcct ggatattggc gcgcaaactc tactgatccc gatggtcgat actgccgatc
     7201 aggcacgtca ggtggtgtct gccacgcgct atcctcccta cggtgagcgt ggtgttgggg
     7261 ccagtgtggc acgggctgct cgctggggac gcattgagaa ttacatggcg cacgtcaacg
     7321 attcgctttg tctgttggtg caggtggaaa gtaagacggc actggataac ctggacgaaa
     7381 tcctcggcgt cgaaggaatt gatggcgtgt ttattggacc tgcggatctt tctgcctcgt
     7441 tgggctaccc ggataacgcc gggcacccgg aagtgcagcg aattattgaa accagcattc
     7501 ggcggatccg tgctgcgggt aaagctgctg gttttctggc tgtggctcct gatatggcgc
     7561 agcaatgcct ggcgtgggga gcgaactttg tcgctgttgg cgttgacacg atgctctaca
     7621 gcgatgccct ggatcaacga ctggcgatgt ttaaatcagg caaaaatggg ccacgcgtaa
     7681 aaggtagtta ttgatatcaa aggcccatgg ggatcggctg tgggcctgtg ttaattagtg
     7741 gttattcgct gccagatcgg cttcgcttag ctgagtggcc gcgagcacct ggtcacgatc
     7801 aatgccctgt tccagcatgc gcaaggcaat tttaatggct tgttcatgca tgccttctaa
     7861 tttaccctcc tgccagccaa tttggtgtcc ttcctgccgt agccgttcag caatagtcat
     7921 taatctctcc ttttaataac agttcggaat atcagcatca gtgagttggg ttgtcgccag
     7981 cacaatctca cgttcaaagc cctgttccag catgcgcaag gcaattttaa tggcttgttc
     8041 atgcatacct tctactttgc ctttctgcaa accctccaac ttcccctcct gccaaccaat
     8101 ttgatgccct tcctgccgta gccgttcagc aatagtcatt aatctctcct tttgtagtgg
     8161 tgaacgttcg gcaatctcct gaataaaacg ggtgaaacgg gaggtatcgc cgcattgcag
     8221 cagataatta aacagtgttt gtagctggct gtcattagtg aagcctctaa ccaaaagcgt
     8281 ggtgatcctg tcgaccatac cgattaaatc gcggtcgcga atatgctttt gaatcagttc
     8341 cagcagagct atacgccgat gttgcatgat ctcatcgtca ggtacgatgg tgatatccac
     8401 caacggaaaa gcttcggtgt acaactgccg ggcaagttgc ggatcatcaa actcatccag
     8461 ccagttaagt gagtatgggt agggcgaggt ttcgccatga taaaacagca acggcaccac
     8521 cagcgggact ctgtcatagc ctttgtccag atggcgctgc atggcggcgg tggcatagcg
     8581 cattagtcga aaagccatat tcttttctgc agaactttga tgttcaatca cgcagtagat
     8641 atagccgtca ccgtcgctgg tttccaccga ccacaaaaca tccgagtagt aagcgcgtaa
     8701 acttttttca ataaaactgg tgggttccag gcgtaaggtt tgcaggttgc aaagcttgcg
     8761 cagtggttct ggtaaatgta tttcgagaaa atcccgtgcg gtttcgggtg tgaacataaa
     8821 ggttttaaat accgcatcat gcggggagga ggttgttgat tcggtcatgg ttgtccgtca
     8881 cctgatattt atgatgacgc gacattacgg ttatcccagg cctttgacat ctgccagttt
     8941 cagtctttgc gagacgtttt cagaggaatt ttcactgcgt tgcaacgtat acattgagcg
     9001 cggaatcgtg cacgcaaaaa tgcccggtaa caacatgctt accgggcatc agaaaggagt
     9061 ttaagccagc gcctgggcca gcagcgtaat cggatgttca cagcgaagac ttgtggacat
     9121 ctcaatctgc catttacagg tttcgcagtc agtgaccacc agatccgcgc cgctttcttc
     9181 tatctgacgg aacagtggtg caccgatggc ttgtgaggtg ggatagttct cttttttgaa
     9241 accgtaagta cccgcaattc cgcagcactg ggaatccagc accgttaact caagccccgg
     9301 gattttacgc aacagctcca gggtgtagag cgtccagccc attttttcca tatggcacgg
     9361 agtgtgataa accactttca gcggcagcgg tttcagcggc aaggttttgc cttcgtccag
     9421 cttgcgccac agccagcggg tcgccagttc gatgtgatcg cgcaagcctt tgttgtcaac
     9481 attcagcact tccgggtact cgtcgcgcag agcaaacgta caggtcgagg aggtagcaat
     9541 caccggaatg ccttttactc ccactgcttc gcggatcgac tctacatttg tgattgcctg
     9601 tttacgtgct ttatcggtaa agccgttggc gatcagcggt acgccgcaac atttttcttt
     9661 gctgagcagt tgtacaccgg tacccattgc gttgagtact ttaattaaat ctttgcctaa
     9721 ctgcggatgg ttgtagttaa cgaagcagcc gtgaaagaaa gccacctggt ctttatattg
     9781 cgcttgttgg gctgccacgc tgcgatacca gcgacggaac gtgccgaagg agtatttcgg
     9841 tagcgtgcga cgatgatcga tttttaacgc cgcatcaagc agctgccgca ccggtttcag
     9901 cgaggtagca gtgttgacga ttggtgcgaa cggcgtggaa acgctaccca tcaggtcggt
     9961 atggcttaaa acaaaattgc gcagcgacgg gcgcgtggtg tcatatttcg cccgtgcgcg
    10021 ctggatgata tcgccaatct tcacatcgga cgggcaggcg acttcgcaac gtttgcagtt
    10081 gatgcaatat ttcagtgcct cgtcatacag tgcgccatcc ttcaaacgca gacgctcgcc
    10141 atccggcccg gcttgttttg gccccggata tcccggattc acccggctca ccgggcaggc
    10201 ggtggtgcag acggtgcact taatgcagtt ttcgaagctg gtgtcgttca ttgttggcct
    10261 cctgcgcgtt gggcaatctg ttgagcggca tgtaaagcac tgacggcaca aacaccgccg
    10321 ccgcatccct gggcgatggg atcaaatccg cccagcaccg aaccgatggc aaacaggttc
    10381 tcaatggttt gccctgcctg cgacgggcgt agtgcctcat cagtggttac accgaactgc
    10441 tgccacggtt gcggcgcaaa aaaatcgccc ttataccatt caccccgcgt ggcggtttgt
    10501 agcacatcaa ggccgagaat cggctctcga atgccgttac gttccgccac cagtccgccg
    10561 ctaaagaaac tgccgctggc gagcacggca aagcgtggac gcagcgggat atcggcgtga
    10621 ttgcgcgtcc agatttcatt tactacgcca tttttacagg tcactttttt cacttcatcg
    10681 cctggcatcc acacgccacc ctggcgcaca aactggcgct gtaactggtt ttgcagacga
    10741 atgcccagca cggaaggcgg cagcgttggc aaaagcatca gtgaacaagg tagtttttca
    10801 ttcaaccaat gccacagttt gtcatcggcc aggccgaagc aggcgggcat caggatcatt
    10861 tcgcaggtat tggcgacagg aataagcgca tcaagtaaca gcggccagtt ctcttcgtta
    10921 tcaaggaaac gggcgatatt caccgcgcga aactcggtgg cgttgttgcg cagcacatcc
    10981 agttccggca gttcaatttc tgcggtttca acggcaaggt cgagttcgcg caacgaagcc
    11041 gccgcaagat gcgcctgaaa atccatcaga ccgctaattc ctactacaca tattttcttc
    11101 gcgggcagcg gccagacggg gacttctggc gcacttagcc aggtagaacg cagggtaccg
    11161 agcggggtaa cacgctggtg ggccagttct acgctgccct gtaattgtgc accgctttca
    11221 gcgattaatg cctgcgcctg gcaagcgaga tcgagtacgc gttgtggccc gagaagagtg
    11281 taaggatggg ctggagcctg ctgacgcaaa gattccagtc cactgtgaat gtctgtcacc
    11341 ggttgaccat ccggcagatg gctcagcaaa tccagcgatc cagatgagaa atgcagcgcg
    11401 ctttgaccac gagtgacaat ggcacagcgc aggccgtgtt tttgcagttg caggccacag
    11461 agtaatccgg cgaggccgcc gcccataatg acagtatcaa agcgcatctt tctgctcctt
    11521 ctccagacca cacagtccct gataaaccca gcgggtaaat tcgctttcgc gcagtgcgtc
    11581 tccccatgct atgggttgca cgcctttcca gcgttcgtta aggaaggtgg aaagttgctc
    11641 gatagattgc gcggacgtcg tgacgttaaa acgttgcagc agtccggcag cgcggcaggc
    11701 gcagagctcg ccctggcagg tgcccatccc cacacgggta cgacggcgta aatccagcag
    11761 gctattaacg tttaaatttt ctaccgcgta ctgcacttca cccgcagtta ccgcttcgca
    11821 ctcacatacc aggctgcggt gcaggcggcc ttcgctcagc caggctggtg tgcgatcgcc
    11881 gtgccggtaa acggcggaac cgcgcagcgg agcgggcagg gagatcactt tgcgcagcgt
    11941 gacttctgcc ggttcctgtg agccaggaag tgccagatcg gcggttgtac aggggcgcgt
    12001 gttgcccagc ttgcgacaca ccgcgtcagt agcccattcc gccatcaggc ggtaggtcat
    12061 cagtttgcca ccggtgatgg tgataaatcc gtccagacca tcgcgttcag catggtcgag
    12121 cagcacgatg ccacggctga cgttacgtcc gctcggatcg tcatcgctgg caaccagcgg
    12181 gcgcacgcca gagtaagccc gcaaaatacg cgttttcgcc atcacggggg ccagtttttc
    12241 cccttcacgc agcagaatat caacttcttc tgccgtcact cgattatcgt caatctcgct
    12301 gtagtcaata cgtaaagagg tggtgccaat cagcgaaatg gtatcgccag gcaccagaat
    12361 atcggcgtca gaaggtttac ggcagcggtt gatcacatgc tgattaatgc ggtgatccat
    12421 aatcagcagc gatcctttcg ccgggaacat gcgaatgcgc agatcggcat attccgcaat
    12481 gtgttgcccc cagatcccgg cggcattaac tacgacaggc gcatgaagtg cctgggtttc
    12541 gccggtgagg tggttacgta cacgaacacc gcacaccgtc gcgccttcac gaatcagccc
    12601 cgtgacttca tgagcggtaa ggataacggc accgtgttct ttggcatcaa gcatatttgc
    12661 tgcggtcaga cgaaatggat caacagtgcc atccggaact ttcaccgcgc caatcagtgc
    12721 cgggttaacg gcaggttcga taatgcgcgc ttgctgcggg tctatagctt ctgcgctgat
    12781 ccctgcttct tcgcaggcgc ggataaaagt ggcctggaag gagaggtcat cttccggcag
    12841 ggtgataaac aggccgttgg tcggttcaac gcagtgacgc gcaatgcgtt tcaggatctg
    12901 gttttcacta atacattcgc gggccgattc cgcatcagtt accgcatagc gcgcaccgct
    12961 gtgtagcagg ccgtggttac gcccggtggc accggttgcg atgtcgtggc gctctaccaa
    13021 aatcacgcgc agcccgcgca gggcacagtc gcgggcaatc ccggctcccg ttgcgccgcc
    13081 gccaatgata atcacgtcac ttgattgcga gtcgcgagtt ttcattgtta tccctctgaa
    13141 gttcgttttt taccatttag ccatagtaaa aacatgaatt gtttgatttc gcgcatattc
    13201 gctcataatt cgaaagtgaa acgtgatttc atgcgtcatt ctgaacattt aaaccatcgt
    13261 atttaataat gtgtgcggta attcacattt aatttatgaa tgttttctta acatcgcggc
    13321 aactcaagaa acggcaggtt ctcccactga atcagtctgt taatcataaa taagaccacg
    13381 ggccacggag gctttcaatg ttgagtattt ttaaaccagc gccacacaaa gcgcgcttac
    13441 ctgctgcgga gatcgatccg acttatcgtc gattgcgctg gcaaattttc ctggggatat
    13501 tctttggcta tgctgcttac tatttggttc gtaagaactt tgcgctcgct atgccttatc
    13561 tggttgagca gggattctca cgcggtgatt taggttttgc cctttcgggg atctcgattg
    13621 cttatggatt ttcgaaattc atcatgggtt cggtatcgga tcgctcgaat ccgcgcgttt
    13681 tcctgcccgc aggtttgatt ctggcggcgg cagtgatgtt gtttatgggc tttgtgccgt
    13741 gggcgacgtc gagcattgcg gtgatgtttg tactgttgtt cctctgcggt tggttccagg
    13801 ggatgggatg gccgccgtgc ggtcgtacta tggtgcactg gtggtcgcag aaagaacgtg
    13861 gcggcattgt gtcagtgtgg aactgtgcgc acaacgtcgg tggtggtatt ccgccgctgc
    13921 tgttcctgct ggggatggcc tggttcaatg actggcacgc ggcgctctat atgcccgctt
    13981 tctgcgccat tctggtggca ctgttcgcct ttgcgatgat gcgcgatacc ccgcaatcct
    14041 gtggcctgcc gccgatcgaa gagtacaaaa atgattatcc ggacgactat aacgaaaaag
    14101 cggaacagga gctgacggcg aagcaaatct tcatgcagta cgtgctgccg aacaaactgc
    14161 tgtggtacat cgctatcgcc aacgtgttcg tttatctgct gcgttacggc atcctcgact
    14221 ggtcaccgac ttatctgaaa gaggtgaaac acttcgcgct ggataaatcc tcctgggcct
    14281 acttcttcta tgagtatgcg ggcattccgg gcaccctgct gtgcggctgg atgtcggata
    14341 aagtcttccg tggcaaccgt ggggccaccg gcgtcttctt tatgacactg gtgaccatcg
    14401 cgactatcgt ttactggatg aacccggcag gtaacccaac cgtagatatg atttgtatga
    14461 ttgttatcgg cttcctgatc tacggccctg tgatgctgat cggtctgcat gcgctggaac
    14521 tggcaccgaa aaaagcggca ggtacggcag cgggctttac cgggctgttt ggttacctgg
    14581 gcggttcggt ggcggcgagc gcgattgttg gctacaccgt ggacttcttc ggctgggatg
    14641 gcggctttat ggtaatgatt ggcggcagca ttctggcggt tatcttgttg attgttgtga
    14701 tgattggcga aaaacgtcgc catcaggaat tactgcaaaa acgcaacgga ggctaatggc
    14761 atgaaattga cgctgaaaaa ccttagcatg gcgatcatga tgagtggaat gatcatggga
    14821 agcagtgcaa tggcggcgga cagcaacgaa aaaatagtca tcgcccatcg cggtgccagt
    14881 ggatatttgc cggagcatac gctgccagca aaagcgatgg cgtatgcgca gggagcggat
    14941 tatctggaac aggatttggt gatgaccaaa gacgaccatc tggttgttct gcatgaccat
    15001 tatctcgatc gtgttactga tgttgccgat cgtttcccgg atcgggcgcg caaagacggt
    15061 cgttactacg cgatagattt cacgctcgat gaaattaagt cactgaaatt taccgaaggt
    15121 ttcgatattg aaaacggtaa gaaagtacag acttatccgg ggcgtttccc aatgggtaag
    15181 tccgacttcc gggtgcacac ctttgaagaa gagattgaat ttgttcaggg gttaaatcac
    15241 tctaccggga aaaatattgg tatctacccg gagattaaag cgccgtggtt ccatcatcag
    15301 gaagggaagg atattgcggc aaaaacgctg gaagtgctga agaaatatgg ttacaccggt
    15361 aaggacgaca aagtttattt gcaatgtttt gatgccgatg aactgaagcg tattaagaat
    15421 gagctggaac ctaaaatggg catggacctc aatctggtac agctgattgc ctataccgac
    15481 tggaacgaaa ctcagcagaa acagccggac ggaagctggg ttaattacaa ctacgactgg
    15541 atgtttacgc cgggggccat gaaacaggtg gcggaatatg ctgatggtat tggtccggat
    15601 taccatatgt tgattgagga gacatcgcag ccaggtaata tcaaactcac tggcatggtg
    15661 caagatgctc agcagaataa actggtagtg catccttaca ccgtgcggtc agataagctg
    15721 cctgaataca ctactgatgt gaatcagtta tatgatgctc tgtataacaa agcgggtgta
    15781 aatgggctgt ttactgattt ccctgataag gcagtaaaat tccttaataa agagtaatgc
    15841 tactgcagga tggcgttcat gcgccatcct gtctcatatc aaattttcca ctctccacta
    15901 attgttctgt gcacatttgt agtaaaaaca gtggactgcc ttctaccggc ttttctttag
    15961 ccagcaacga aatctgtcga tagaaggttg gttcgagagg aacggaacac aattcatctg
    16021 caatggtttt cagcgttaac tctggtaata aggcgatgcc taatccctgt cgaataaaac
    16081 tgatcgctgt atccgggtga ttaaattcat attttatctg tggggtaata ttcttttctt
    16141 taaatagtgc cataatgctt aattcatagc gtcctttact aataattaat ggttcaccca
    16201 ttaactcttc cactgtaata gtgctgtttt ttgccagagc atggtagggc ggtaacacta
    16261 cggtgaattt atcctgataa atgggcacgg agtacattcc gctcaccgga aaatgaacaa
    16321 aaccggcatc aatggattca ttctgaaggg aatcaataat cgctgtgcta ttttcctcaa
    16381 aaggaataat ttttatattc ggatgatgaa tttcaaagta gcgaatcaca gccggtaaga
    16441 tacaggcgca gacgctgggg aaacaaccaa gtctcagcgt tctttgaggg ttctgctttt
    16501 cctgctcggc tatctctttt actgcgttca cttcccgatt aatggcgcgc agatgatgca
    16561 taatgcggtg acctgcagag gtcagttgta tagctttacg gcgatctcgt aacagtatat
    16621 tcacgccaag ttcttgttcg agggcagcaa ttgcctgact taccgccgac tgcgtcatga
    16681 acaatcgctt gctggcttca gtaaagccac cgtaatccag cacggcgagt aaagaattta
    16741 tttgggtaag agtcattaga gtttgctaat caataatatt aaaacgatta atttctctaa
    16801 tagcatgccg ccatttatac ttctgttatg caaagtacat cacaatttga cgcaaccgca
    16861 gtaacgggag tgttgtctgc gtgcgtcatc ctgacaggcg gtagggtatg aaagagaagt
    16921 tatggacgaa ggatttttgg gcaataacca tcatcagttt tattattttc ttcgtctttt
    16981 atgttttact aacattgttg ccaatttata tctcagaccg cttgcatgcc tctcctgata
    17041 aagcaggttt gttggtgact ttatttttaa ttgccgccat tgttattcgc ccctttgccg
    17101 ggcaatgggt gggcaaatat tccaataaaa ctattctggg gctctcttct ctggccttct
    17161 tggtggtcac tgcgctgtat cctttttgcc actcaattga atcactgctt tttattcggg
    17221 tgcttcatgg tattaccttc ggggttatca ctacggtaaa aggaacgatt tccgcgcggc
    17281 tgatcccggc ctcccgacgt ggggagggca tcagtttttt ctctctggca atggggctgg
    17341 caatggtggt cgggccgtgg attggcctga atatggcgcg ctgggaggcc tttaatatgg
    17401 ctttctggtt atgcaccggc gtggcagcgg tggggattat tctgtcgctg attatgacag
    17461 tgccgccggt tatcagccat actgatggtt caacgccgaa aatgggcttc gccgccatgt
    17521 tcgatcgcgc ggcgttgcca tttgcgatgg tcaccttttt tatgaccttt tcgtatgccg
    17581 gggtttctgc ttttctggcg ctttatgcac gcgaacttaa cctgatgtcg gcagccagta
    17641 atttcctgct ttgctacgct atcttcctga tgatctgccg tacctttacc ggcaatgtct
    17701 gcgacaaaaa aggaccgaaa tatgtggttt acccttgcct tgtgttcttt acggtaggac
    17761 tggtggttct cggctacacc cagggaagca taatgatggt tgtttctggc gcattgattg
    17821 gtatcgggta tggttccgtg acgccagttt ttcagacgca gattatcagt tcagtggaac
    17881 cgcataaaat cggtgtcgca aactccctct tcttcaatgc gatggatgca ggcctggcgc
    17941 tgggagcctg tgtgatgggg atgatggttg cacatactgg ctaccgaatg atttatctgc
    18001 tgggtgcact attagtggta gtggctggtg gagtctatgc gctgcaaatg aagggcaaaa
    18061 gcggtgtcat gctagtagcg gcaaaagaaa ttcattaata cgacacgttt cattaagatt
    18121 tttcgcaggt aaccacctat agtcattgtc gtaaataaaa aatgacaggc gatagggtat
    18181 ggcagtttca gcaaagcacg acgaatttaa tcactggtgg gcaacagagg gcgactgggt
    18241 tgaagagcct aactatcgcc gtaatggtat gagcggggtg caatgcgtcg agcgcaacgg
    18301 caaaaagcta tatgtaaagc gcatgacgca tcatctgttt cattccgtac gttatccgtt
    18361 cggtcgacca acgattgtcc gtgaggttgc ggtaattaaa gaactggaac gggctggtgt
    18421 catcgtgccg aagatcgttt ttggtgaagc ggtgaaaatt gagggggaat ggcgcgcgtt
    18481 gctggtgact gaagatatgg cggggttcat cagcattgct gactggtatg cccggcatgc
    18541 agtatcgcct tattctgacg aagtacggca agccatgttg aaagcagtgg cgctggcgtt
    18601 taagaaaatg catagcgtta atcgtcagca tggctgttgt tatgttcgcc atatctatgt
    18661 gaaaacagaa ggtaaggcag aagctggatt tcttgacctg gagaaaagtc gtcgccgctt
    18721 gcgtcgtgat aaagcgatta atcatgactt ccgccagctg gaaaaatatc tggagccgat
    18781 ccccaaagcg gactgggagc aggtgaaagc atattactac gctatgtaat cgttgtaggc
    18841 cagataagac gtataagcgt cgtatctggc gttaaaacca attcacatct cgatttcaat
    18901 atcgcctttt gcccggcaac aacagggcaa aatttccccc ggctgaataa aagctaacgg
    18961 ttcggcaatc cagtccacct ggcctgcgac cagtcgggtg cgacaggagc cgcagtaacc
    19021 ttcgcggcac tggtactcaa ccgccacatt gtgggattcc agcgccgcca gaagggaagg
    19081 gtgttcatcc tggcacagca gttgtgtgcc agtaatgcgc agggtaacgc gggccatcag
    19141 agctggaagt tactcaaatc gtcggtgtcc acttccgcgt caatctgacc gaccagataa
    19201 gaactgactt ccacttcctg cggagcaacc tgcacgttat cagacaccag ccaggtgttg
    19261 atccacggga tcgggttgga gcgcgtctgg aacggcagat ccaaaccgac tgcctgcata
    19321 cggatattgg tgatgtattc aacgtactgg cagaggatgt ctttattcag accaatcatc
    19381 gaaccatcac ggaacagata atccgcccag tctttctctt gctgtgccgc ctggacaaac
    19441 aggtcatagc actcctgctt acattcttcg gcaatttccg ccatctccgg atcatccgcg
    19501 ccgctgcgca gcagattcag catatgctgg gtgccggtca ggtgtagggc ttcgtcacgg
    19561 gcaatcaagc gaataatctt ggcgttgcct tccatcagtt cgcgttccgc aaatgcgaaa
    19621 gaacaagcaa agctgacata gaaacgaatc gcttccagcg cgttaacgct catcaggcag
    19681 agatacagtt ttttcttcag ctcacgtagg ctaacggtca cggttttacc gttgacggtg
    19741 tgggtgcctt cgcccagcag atgccagtag ctggtcattt cgatcagttc atcgtaatag
    19801 ctggagatcc cttccgcacg tttctggatc tgctcgttag tgacgatatc gtcaaagaca
    19861 actgacggat cgttaacgat attacggatg atatgggtat aggagcggga atgaatcgtt
    19921 tctgagaacg cccaggtttc gacccaggtt tccagttccg ggatcgagat cagcggcagc
    19981 agtgccacgt tcgggctgcg accctgaatg gagtccagca gcgtctgata tttcaggttg
    20041 ctgataaaga tgtgtttttc gtgttcaggc agtgcctggt aatcgatacg gtcacgagaa
    20101 acgtcaactt cttccggacg ccagaagaaa gagagctgct tttcgatcag cttttcgaag
    20161 atgtcatatt tttgctgatc gtagcgagcc acgttgaccg gctgaccaaa gaacatcggt
    20221 tctttcagct gatcattttt cgtctgtgaa aaggtggtat atgccatgaa tgtgtcctgt
    20281 tgggagttta atgccggata aggcatttta cgccgcatcc tgtgcctgat gcgacgctgg
    20341 cgcgtcttat caggcctaca aaccgagccg taggccagat aaggcgttca cgccgcatcc
    20401 ggcatctcaa aatcagatct tacatgcgcc gctttcgcag ccatcgtcct ggattgacgg
    20461 caccagatcg tcttgtgcgt cttcagcacc gtcacgggtg ttctgataat acagcgtttt
    20521 gaccccgaat ttgtaggcgg tgagcaggtc tttcagcaac tgctgcatcg gcacttttcc
    20581 tgacgggaaa cgtgatggat cgtagttggt gttagcagag atcgactgat cgataaattt
    20641 ctgcatgata cccaccagtt gcagatagcc atcgttaccc ggcatttccc acagcagctc
    20701 ataggcgtcg tgcagatgct cgtagtccgg caccacctgg cgcagaatac cgtctttcga
    20761 cgctttgatg ctgacgtaac cacgcggcgg ttcaataccg ttagtggcgt tagagatctg
    20821 cgaagaagtc tctgacggca tcagagcaga aagcgtggag ttacgcaggc cgtgcgtttt
    20881 gattgactca cgcagtgctt cccagtcgta atgcagcggc tcattagcga tggcatccag
    20941 atctttctta taggtatcga tcggcaggat ccctttcgcg taagtggttt cgttaaacca
    21001 cgggcacgcg ccttgctctt tcgccagctc attagacgct ttcagcaggt aatactgaat
    21061 ggcttcgaag gttttatgcg tcaggttgtt ggcgctgccg tcggagtagc gtttaccgtg
    21121 cttcgccagg tagtaagcga agttgatcac accaataccc agcgtacgac gccccatcgc
    21181 tccacgttta gcggccggga tcgggtaatc ctgataatcc agcagtgcgt cgagtgcgcg
    21241 aaccgccaga attgccagct cttccagttc atccaggctg ttaattgcgc ccaggttgaa
    21301 agcagacagc gtacacagcg cgatttcacc gttctcgtcg ttgacgtcgt tcagcggttt
    21361 ggtcggcagg gcgatttcca ggcacaggtt agactggcgc actggcgcga tgaccggatc
    21421 aaacgggcta tgggtattgc agtggtcaac gttctgaata tagatacgac cggtagacgc
    21481 acgttcctgc atcatcagcg agaacagctc aacggctttc acacgctgct tgcggatgct
    21541 gtcgtctttc tcatatttgg tatacaggcg ttcaaactct tcctgatcgg cgaagaacgc
    21601 gtcgtacagc cccggtacgt cggacgggct gaacagagtg atatcttcac ctttcagcag
    21661 acgggtatac atcagtttgt tgatttgaac cccgtagtcc atatgacgca cgcggttgcc
    21721 ttccacacca cggttgtttt tcaacaccag caggctttcc acttccagat gccacatcgg
    21781 gtagaacagc gttgccgcac cgccacgcac accgccctga gagcaggatt tcaccgctgt
    21841 ctggaaatgc ttatagaacg gaatacaacc ggtatggaac gcttcgccac cgcgaatcgg
    21901 gctacccagc gcacgaatac gcccggcatt gatgccgatc ccggcacgct gggaaacgta
    21961 tttaacaatc gcgctggagg tggcgttaat ggaatccagg ctgtcgccgc actcgatcag
    22021 tacgcaggag ctgaactgac gagtcggggt acgcacgccg gacatgattg gcgtcggcag
    22081 cgaaatttta aatgtggaaa ccgcgtcgta aaaacgcttc acgtattgca ggcgcgtttc
    22141 acgcgggtag ttcgagaaca ggcacgcggc aaccagaata taaaggaact gggcgctttc
    22201 gtagatttcg ccggtcacgc ggttctgcac cagatatttg ccttccagct gtttaacggc
    22261 agcataagag aaggtcatat cacggtcgtg atcgataaac gtgtccatct gcttgaactc
    22321 ttcttccgtg tagtcttcca gcagatgatt atcgtatttg cccatcacga ccattttcac
    22381 cacgtggtcg tacagcgcag gcggctcaaa ctggccgtag gcttttttac gcaggtggaa
    22441 gatcgccagg cgcgcggcga gatactgata atccggcgca tcacgggaga tcaggtctgc
    22501 ggcagccttg ataatggttt cgtggatgtc agaggtcttg ataccgtcat aaaactgaat
    22561 gtgggagcgc agttcgacct gggaaatcga aacgttatgc agtccttctg ccgcccaatc
    22621 cagaacgcga tggattttgt cgagattgat gcgctctgtg ctaccgtcgc gctttgtcac
    22681 cagcagattc tgattcatgt atgtcgtacc tgtttttgga attctttccg caatagtttc
    22741 atgcagacta cctgtagtga gggaagctgc ttagaacact atatataggg ggtatgtttg
    22801 ggattcactg caagatagtg tgaaaatggc cctcttgcaa gtgcataact ttgtggataa
    22861 ctcaggaagg aaaaagtggc tttcgcgcac cttaggtcag acaaggtgtc cgggaaagtc
    22921 aatgggaaga gaaaaatttg ttaaaaataa ctgttcggcg atttcttgaa cggaagaata
    22981 ggttagataa attgatatag atggtttatt aatcttttgg ctaatgattg caaaaattga
    23041 tctaagcacg agtcatcaca taatctgatg tatcagttat ggtcaatata taagcgaatg
    23101 taagcgattg ttgatgtcga aatggttgtt ttctcttcgg ttgttgttaa atgcgaagcc
    23161 attttgttaa tttaccttat attataagaa
//
LOCUS       DADXDL010000073        22917 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.073, whole genome shotgun sequence.
ACCESSION   DADXDL010000073 DADXDL010000000
VERSION     DADXDL010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22917)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22917)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22917
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.073"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(125..1138)
                     /gene="argF"
                     /locus_tag="IRB70_003387"
     CDS             complement(125..1138)
                     /gene="argF"
                     /locus_tag="IRB70_003387"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBC0633261.1"
                     /translation="MSGFYHKHFLKLLDFTPAELNSLLQLAAKLKADKKSGKEEAKLT
                     GKNIALIFEKDSTRTRCSFEVAAYDQGARVTYLGPSGSQIGHKESIKDTARVLGRMYD
                     GIQYRGYGQEIVETLAEYAGVPVWNGLTNEFHPTQLLADLLTMQEHLPGKAFNEMTLV
                     YAGDARNNMGNSMLEAAALTGLDLRLVAPQACWPEAALVTECRALAQQNGGNITLTED
                     VAKGVEGADFIYTDVWVSMGEAKEKWAERIALLREYQVNSKMMQLTGNPEVKFLHCLP
                     AFHDDQTTLGKKMAEEFGLHGGMEVTDEVFESAASIVFDQAENRMHTIKAVMVATLSK
                     LNN"
     gene            1300..1716
                     /gene="rraB"
                     /locus_tag="IRB70_003388"
     CDS             1300..1716
                     /gene="rraB"
                     /locus_tag="IRB70_003388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease E inhibitor RraB"
                     /protein_id="HBC0633262.1"
                     /translation="MANPEQLEEQREETRLIIEELLEDGSDPDALYTIEHHLSADDLE
                     TLEKAAVEAFKLGYEVTDPEELEVEDGDIVICCDILSECALNADLIDAQVEQLMTLAE
                     KFDVEYDGWGTYFEDPNGEDGDDEDFVDEDDDGVRH"
     gene            complement(1861..2364)
                     /locus_tag="IRB70_003389"
     CDS             complement(1861..2364)
                     /locus_tag="IRB70_003389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBC0633263.1"
                     /translation="MNNIAPQSPVMRRLTLQDNPAIARVIRQVSAEYGLTADKGYTVA
                     DPNLDELYQVYSQPGHAYWVVEYEGEVVGGGGIAPLTGSESDICELQKMYFLPAIRGK
                     GLAKKLALMAMEQAREMGFKRCYLETTAFLKEAIALYEHLGFEHIDYALGCTGHVDCE
                     VRMLREL"
     gene            2556..3752
                     /locus_tag="IRB70_003390"
     CDS             2556..3752
                     /locus_tag="IRB70_003390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF898 domain-containing protein"
                     /protein_id="HBC0633264.1"
                     /translation="MAQVINEMDVPSHSFVFHGTGERYFLICVVNVLLTIITLGIYLP
                     WALMKCKRYLYANMEVNGQRFSYGITGGNVFVSCLIFVFFYFAILMTVSADMPLVGCV
                     LTLLLLVLLIFMAAKGLRHQALMTSLNGVRFSFNCSMKGFWWVTFFLPILMAVGMGTV
                     FFISTKMLHANSSSSVIISMVLMAIVGIVSIGIFNGTLYSLVMSFLWSNTSFGIHRFK
                     VKLDTTYCIKYAILAFLALLPFLAVAGYIIFDQILNAYDSSVYANDDIENLQQFMEMQ
                     RKMIIAQLIYYFGIAVSTSYLTVSLRNHFMSNLSLNDGRIRFRSTLTYHGMLYRMCAL
                     VVISGITGGLAYPLLKIWMIDWQAKNTYLLGDLDDLPLINKEEQPDKGFLASISRGIM
                     PSLPFL"
     gene            complement(3808..6663)
                     /gene="valS"
                     /locus_tag="IRB70_003391"
     CDS             complement(3808..6663)
                     /gene="valS"
                     /locus_tag="IRB70_003391"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBC0633265.1"
                     /translation="MEKTYNPQDIEQPLYEHWEKQGYFKPNGDESQESFCIMIPPPNV
                     TGSLHMGHAFQQTIMDTMIRYQRMQGKNTLWQVGTDHAGIATQMVVERKIAAEEGKTR
                     HDYGREAFIDKIWEWKAESGGTITRQMRRLGNSVDWERERFTMDEGLSNAVKEVFVRL
                     YKEDLIYRGKRLVNWDPKLRTAISDLEVENRESKGSMWHIRYPLADGAKTADGKDYLV
                     VATTRPETLLGDTGVAVNPEDPRYKDLIGKYVILPLVNRRIPIVGDEHADMEKGTGCV
                     KITPAHDFNDYEVGKRHALPMINILTFDGDIRESAQVFDTKGNESDVYSSEIPAEFQK
                     LERFAARKAVVAAVDALGLLEEIKPHDLTVPYGDRGGVVIEPMLTDQWYVRADVLAKP
                     AVEAVENGDIQFVPKQYENMYFSWMRDIQDWCISRQLWWGHRIPAWYDEAGNVYVGRN
                     EDEVRKENNLGADVVLRQDEDVLDTWFSSALWTFSTLGWPENTDALRQFHPTSVMVSG
                     FDIIFFWIARMIMMTMHFIKDENGKPQVPFHTVYMTGLIRDDEGQKMSKSKGNVIDPL
                     DMVDGISLPELLEKRTGNMMQPQLADKIRKRTEKQFPNGIEPHGTDALRFTLAALAST
                     GRDINWDMKRLEGYRNFCNKLWNASRFVLMNTEGQDCGFNGGEMTLSLADRWILAEFN
                     QTIKAYREALDSFRFDIAAGILYEFTWNQFCDWYLELTKPVMNGGTEAELRGTRHTLV
                     TVLEGLLRLAHPIIPFITETIWQRVKVLCGITADTIMLQPFPQYDASQVDEAALADTE
                     WLKQAIVAVRNIRAEMNIAPGKPLELLLRGCSADAERRVNENRGFLQTLARLESITVL
                     PADDKGPVSVTKIIDGAELLIPMAGLINKEDELARLAKEVAKIEGEISRIENKLANEG
                     FVARAPEAVIAKEREKLEGYAEAKAKLIEQQAVIAAL"
     gene            complement(6663..7106)
                     /gene="holC"
                     /locus_tag="IRB70_003392"
     CDS             complement(6663..7106)
                     /gene="holC"
                     /locus_tag="IRB70_003392"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004098129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit chi"
                     /protein_id="HBC0633266.1"
                     /translation="MKNATFYLLDNDTTVDGLSAVEQLVCEIAAERWRSGKRVLIACE
                     DEKQAYRLDEALWARPAESFVPHNLAGEGPRGGAPVEIAWPQKRSSSPRDILISLRTS
                     FADFATAFTEVVDFVPYEDSLKQLARERYKAYRVAGFNLNTATWK"
     gene            complement(7365..8876)
                     /gene="pepA"
                     /locus_tag="IRB70_003393"
     CDS             complement(7365..8876)
                     /gene="pepA"
                     /locus_tag="IRB70_003393"
                     /EC_number="3.4.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucyl aminopeptidase"
                     /protein_id="HBC0633267.1"
                     /translation="MEFSVKSGSPEKQRSACIVVGVFEPRRLSPIAEQLDKISDGYIS
                     ALLRRGELEGKPGQTLLLHHVPNVLSERILLIGCGKERELDERQYKQVIQKTINTLND
                     TGSMEAVCFLTELHVKGRNNYWKVRQAVETAKETLYSFDQLKTNKSEPRRPLRKMVFN
                     VPTRRELTSGERAIQHGLAIAAGIKAAKDLGNMPPNICNAAYLASQARQLADSYSKNV
                     ITRVIGEQQMKELGMHSYLAVGQGSQNESLMSVIEYKGNASEDARPIVLVGKGLTFDS
                     GGISIKPSEGMDEMKYDMCGAAAVYGVMRMVAELQLPINVIGVLAGCENMPGGRAYRP
                     GDVLTTMSGQTVEVLNTDAEGRLVLCDVLTYVERFEPEAVIDVATLTGACVIALGHHI
                     TGLMANHNPLAHELIAASEQSGDRAWRLPLGDEYQEQLESNFADMANIGGRPGGAITA
                     GCFLSRFTRKYNWAHLDIAGTAWRSGKAKGATGRPVALLAQFLLNRAGFNGEE"
     gene            9143..10243
                     /gene="lptF"
                     /locus_tag="IRB70_003394"
     CDS             9143..10243
                     /gene="lptF"
                     /locus_tag="IRB70_003394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptF"
                     /protein_id="HBC0633268.1"
                     /translation="MIIIRYLVRETLKSQLAILFILLLIFFCQKLVRILGAAVDGDIP
                     ANLVLSLLGLGVPEMAQLILPLSLFLGLLMTLGKLYTESEITVMHACGLSKAVLVKAA
                     MILAVFTAIVAAVNVMWAGPWSSRHQDEVLAEAKANPGMAALAQGQFQQATNGSSVLF
                     IESVDGSDFKDVFLAQIRPKGNARPSVVVADSGHLTQLRDGSQVVTLNQGTRFEGTAL
                     LRDFRITDFQDYQAIIGHQAVVLDPNDTDQMDMRTLWNTDTDRARAELNWRITLVFTV
                     FMMALMVVPLSVVNPRQGRVLSMLPAMLLYLLFFLIQTSLKSNGGKGKLDPTLWMWTV
                     NLIYLALAIVLNLWDTVPVRRLRASFSRKGAV"
     gene            10243..11325
                     /gene="lptG"
                     /locus_tag="IRB70_003395"
     CDS             10243..11325
                     /gene="lptG"
                     /locus_tag="IRB70_003395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313266.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPS export ABC transporter permease LptG"
                     /protein_id="HBC0633269.1"
                     /translation="MQPFGVLDRYIGKTIFTTIMMTLFMLVSLSGIIKFVDQLKKAGQ
                     GSYDALGAGMYTLLSVPKDVQIFFPMAALLGALLGLGMLAQRSELVVMQASGFTRMQV
                     ALSVMKTAIPLVLLTMAIGEWVAPQGEQMARNYRAQAMYGGSLLSTQQGLWAKDGNNF
                     VYIERVKGDEELGGISIYAFNENRRLQSVRYAATAKFDPEHKVWRLSQVDESDLTNPK
                     QITGSQTVSGTWKTNLTPDKLGVVALDPDALSISGLHNYVKYLKSSGQDAGRYQLNMW
                     SKIFQPLSVAVMMLMALSFIFGPLRSVPMGVRVVTGISFGFVFYVLDQIFGPLTLVYG
                     IPPIIGALLPSASFFLISLWLLMRKS"
     gene            complement(11486..12988)
                     /locus_tag="IRB70_003396"
     CDS             complement(11486..12988)
                     /locus_tag="IRB70_003396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF853 domain-containing protein"
                     /protein_id="HBC0633270.1"
                     /translation="MSEPLLIARTPDTELFLLPGMANRHGLITGATGTGKTVTLQKLA
                     ESLSEIGVPVFMADVKGDLTGIAQAGTASEKLLARLKNIGVNDWQPHANPVVVWDIFG
                     EKGHPVRATVSDLGPLLLARLLNLNDVQSGVLDIIFRIADDQGLLLLDFKDLRAITQY
                     IGDNAKSFQNQYGNISSASVGAIQRGLLSLEQQGAAHFFGEPMLDIKDWMRTDANGKG
                     VINILSAEKLYQMPKLYAASLLWMLSELYEQLPEAGDLEKPKLVFFFDEAHLLFNDAP
                     QVLLDKIEQVIRLIRSKGVGVWFVSQNPSDIPDNVLGQLGNRVQHALRAFTPKDQKAV
                     KAAAQTMRPTPAFDTEKAIQELGTGEALISFLDAKGSPSVVERAMVIAPCSRMGPVTE
                     DERNGLINHSPVYGKYEDDVDRESAYEMLQKGVQASTEQQNNPPAKGKEVAVDDGILG
                     GLKDILFGTTGPRGGKKDGVVQTMAKSAARQVTNQIVRGMLGSLLGGRKR"
     gene            complement(13118..14137)
                     /gene="ahr"
                     /locus_tag="IRB70_003397"
     CDS             complement(13118..14137)
                     /gene="ahr"
                     /locus_tag="IRB70_003397"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent aldehyde reductase Ahr"
                     /protein_id="HBC0633271.1"
                     /translation="MSMIKSYAAKEAGGELEVYEYDPGELKPQDVEVQVDYCGICHSD
                     LSMIDNEWGFSQYPLVAGHEVIGRVVALGSAAQDKGLQVGQRVGIGWTARSCGHCDAC
                     ISGNQINCEQGAVPTIMNRGGFAEKLRADWQWVIPLPENIDIESAGPLLCGGITVFKP
                     LLMHHITATSRVGVIGIGGLGHIAIKLLHAMGCEVTAFSSNPAKEQEVLAMGADKVVN
                     SRDPQALKALAGQFDLIINTVNVNLDWQPYFEALTYGGNFHTVGAVLTPLSVPAFTLI
                     AGDRSVSGSATGTPYELRKLMRFAARSKVAPTTELFPMSKINDAIQHVRDGKARYRVV
                     LKADF"
     gene            14333..14417
                     /locus_tag="IRB70_003398"
     tRNA            14333..14417
                     /locus_tag="IRB70_003398"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:14367..14369,aa:Leu,seq:caa)
     gene            complement(14931..15845)
                     /locus_tag="IRB70_003399"
     CDS             complement(14931..15845)
                     /locus_tag="IRB70_003399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000908169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633272.1"
                     /translation="MLIQKKRIRNIDNYIPNFDGRDIYIAHSLPDAGKTDSIGFSSQR
                     ALGEEVLPKILGPITRFNANGKSVPDKTAPKETAYRQISWTRKQWIGGGATQEVTDTR
                     EIEYKRYKRILTPPPSIELKIVENLQGEKLIISPKLSLTANNKELVAHCINLFLELFG
                     LCETVDDQLNTIVKSKSIKLNWSLLPQGQQPWSTIGSKILSAIKIRGKGNTAVVEGRL
                     ELINSKKPDFVAVGQAGFQGYVIFGFTGQNIYVLESSQCNNATYILNNNWQQLSQLTK
                     AEILDGNLHHARVIHRVNWAAEILKYLP"
     gene            16821..17381
                     /locus_tag="IRB70_003400"
     CDS             16821..17381
                     /locus_tag="IRB70_003400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001403343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBC0633273.1"
                     /translation="MATFGYGRVSTSQQDTENQRLELGQAGWQIDYWFADVVSGKVPA
                     MQRKAFSEMLNKIRDGETLVVAKLDRLGRDAIDVLQTVRALADRNIKVLVHQLGNTDL
                     TSAAGKLLLSMLAAVAEMERDLLIERTQAGLSRAKAEGKKLGRPPKIASEARREILEK
                     KNSGLSISALARQYGVSRATVAAITD"
     gene            17395..18240
                     /locus_tag="IRB70_003401"
     CDS             17395..18240
                     /locus_tag="IRB70_003401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633274.1"
                     /translation="MAYTATVIPVMIASPGDVAEERQVIREMIHEWNDINSARSKVML
                     TPIGWETHTSPELGVRPQKLINQRLLVDCDLLIGVFWTRLGSPTGNEASGTVEEIHRH
                     LNAGKPAMIYFSSKPVAPESLDREQYESLKLFKTECMQKGLIESFNDLSDFKDKVRRQ
                     LSIIISSSPYLSSLISTINNSPDANTSQSLPESNLSADALSLLKLACVDDSGTIYVIR
                     HLGGTDIQAGNQSFGGSSAREVARWEGALNELLSFDYVIERGAKGQMYYVTHKGWTFL
                     ESLNE"
     gene            complement(18301..18795)
                     /locus_tag="IRB70_003402"
     CDS             complement(18301..18795)
                     /locus_tag="IRB70_003402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001691323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633275.1"
                     /translation="MTGADFLLPIAAGAAISWASYSVVAHAVSKQHISTLRATVWGAL
                     GTLSLVLGVCAFSAVGAEHQTARKDIVCADDNPECYAKTHHNPVRECKKVMDEKAKFR
                     HVWQESEAPVFNTYLWHDENAKIIQAFGQQAKVVNGLGMLAPLQYFCVFNAKTGEVIA
                     ASFE"
     gene            19036..19500
                     /locus_tag="IRB70_003403"
     CDS             19036..19500
                     /locus_tag="IRB70_003403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000749342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0633276.1"
                     /translation="MKKSLRIQFGERVKELRIATGLSQEAFADRCGFARSYMSRIERG
                     GSNASLDAIEVLANALSVEPWQLLAPGPSEDNDSELLVPYAADGSCFHPGLASTRDGS
                     FGVGDKAAQKRFGTFAEALEYLRSMETAKWRRPNPSGNWGIVSAVRWDKLRK"
     gene            20202..20648
                     /locus_tag="IRB70_003404"
                     /pseudo
     CDS             20202..20648
                     /locus_tag="IRB70_003404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001218945.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="integrase arm-type DNA-binding domain-containing
                     protein"
     gene            complement(20645..20800)
                     /locus_tag="IRB70_003405"
                     /pseudo
     CDS             complement(20645..20800)
                     /locus_tag="IRB70_003405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608786.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoethanolamine transferase"
     gene            21387..21617
                     /locus_tag="IRB70_003406"
                     /pseudo
     CDS             21387..21617
                     /locus_tag="IRB70_003406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546148.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            21990..22235
                     /locus_tag="IRB70_003407"
                     /pseudo
     CDS             21990..22235
                     /locus_tag="IRB70_003407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
     gene            complement(22286..22564)
                     /locus_tag="IRB70_003408"
                     /pseudo
     CDS             complement(22286..22564)
                     /locus_tag="IRB70_003408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244358.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         5525 a         5681 c         5716 g         5995 t
ORIGIN      
        1 attaaatcct ccggaaaatt tacgtatagc aatagaaaaa tttggctgga agaaaaaact
       61 atcactgcat aaaataatgt gatgccggga tgtttttgta tttcccggca tcttgataga
      121 gatattaatt atttaattta ctgagcgtcg cgaccatcac cgctttgata gtatgcatac
      181 ggttttccgc ctgatcaaaa acaatgctgg cggcagattc gaagacctca tcagtcactt
      241 ccattccgcc atgtaggcca aactcttccg ccattttctt gccaagcgtc gtttggtcgt
      301 catgaaacgc gggcaggcag tggaggaatt tgacctccgg gttaccggtc aactgcatca
      361 tcttgctgtt cacctgatat tcacgcagta atgcaatccg ttccgcccat ttctcttttg
      421 cttcccccat cgacacccac acatcggtat agataaagtc agcaccttca actcccttcg
      481 cgacatcttc cgtcagcgta atattcccac cattttgctg tgccagggcg cggcattccg
      541 taaccagcgc agcttccggc cagcatgcct gcggcgcgac cagacgcaaa tccagaccgg
      601 taagcgccgc agcttcgagc atcgaattgc ccatattgtt acgcgcgtca cctgcataaa
      661 ccagcgtcat ttcgttgaac gctttgccgg gcaaatgctc ctgcatggtg aggagatccg
      721 ccagaagctg cgtggggtga aactcattgg tcaggccgtt ccataccggc acgccagcgt
      781 attccgccag tgtttcgaca atctcctgac catagccgcg atactgaata ccgtcataca
      841 tgcgaccaag cacgcgggca gtgtctttaa tcgactcttt atgaccaatc tggctgccgc
      901 ttgggccgag ataagtaacg cgagcaccct ggtcatatgc ggcaacttcg aaagagcatc
      961 gggtacgagt cgagtctttt tcgaagatga gcgcgatgtt tttaccagtg agtttggctt
     1021 cttctttacc gcttttctta tcggctttca gcttcgcggc taactgcagc aggctgttga
     1081 gttcagctgg cgtgaaatcg agtaatttca ggaaatgctt atgataaaac ccggacatag
     1141 atccctcctg tggctaacgc ctcaatgaat taaaattcaa tttatatgga tgattattca
     1201 tttgcaagtc taaagcataa atctttgtca caaaggtgga ggcaatgtca gtggtgtgtg
     1261 acaataagag tatcggcagg acattaagag gaatgagcca tggcaaaccc ggaacaactg
     1321 gaagaacagc gtgaagaaac acgtttgatt attgaagaat tactggaaga tggcagcgat
     1381 ccggacgcgc tgtacaccat cgaacaccat ctttccgcag acgatctgga aacactggaa
     1441 aaagcagcag ttgaagcgtt taaactcggt tacgaagtga ccgatccaga agagctggaa
     1501 gttgaagatg gtgacatcgt gatttgctgc gacatcctca gcgagtgcgc gttgaatgcc
     1561 gatctgatcg atgcccaggt tgaacaactg atgacgctgg cagagaaatt tgacgttgag
     1621 tacgacggtt ggggcactta ctttgaagat cctaacggcg aagatggcga cgatgaagat
     1681 tttgtcgatg aagacgatga cggagttcgc cactaattaa gcgttgcgca tcaggcccag
     1741 gtagttcctg caacctggtg aatttgttgc ccggataagg cattcatgtc acatccggca
     1801 taaacaaaac gtacgttgtt aatgttcgaa tgcccgcgag ttgaacacgc gggcattttt
     1861 ttagagttcg cgcaacatcc gcacttcaca atcgacatgg cccgtgcagc caagcgcata
     1921 gtcgatatgc tcaaagccca aatgctcata aagcgcaatg gcttccttta aaaaagcggt
     1981 cgtttccaga tagcagcgtt tgaaacccat ctctcgcgcc tgctccatcg ccattaaggc
     2041 cagttttttt gccagccctt tgccgcggat agccggaaga aaatacatct tttgcagttc
     2101 gcaaatatcc gactcactcc cggttaatgg cgctatccca ccgccgccga ccacttcacc
     2161 ctcgtactca acgacccaat atgcatggcc aggctgacta tacacttgat acagctcgtc
     2221 aagattcgga tcggcgacgg tgtagccttt atcagcggta agaccgtatt cggcggatac
     2281 ctgacgaatg acgcgggcga tagcaggatt atcctgcagc gtcaggcgac gcattacagg
     2341 tgattgcggc gcaatgttat tcatagttta acccaataaa aataaagtaa ttatacattt
     2401 gtttaatacc actctcttct tacgtgcgca agcgacttat aagtaataaa gtttttgcca
     2461 gcctattact gataagagta ttgtaacgtg gcagaacatt ttactgtctg tatatataag
     2521 ttatatcaat ggatttttta attcagggaa tttttatggc tcaagttatt aatgaaatgg
     2581 atgttccgtc ccattcgttt gtttttcatg gtacaggtga gagatatttt cttatttgtg
     2641 tggtgaatgt gttgttaacg attataacgc taggtatcta tttaccatgg gcattaatga
     2701 aatgtaagcg ttatctttat gctaatatgg aagttaacgg acaacgattt tcttatggaa
     2761 taaccggtgg gaatgttttt gttagttgtc ttatttttgt ttttttctat ttcgcaatct
     2821 taatgacagt gtcagcagat atgccgcttg ttggttgtgt tttgactttg ttactgttgg
     2881 ttttgcttat atttatggca gcaaaaggac tgcgtcatca ggccttaatg accagtctca
     2941 acggcgtaag atttagtttt aattgctcta tgaaagggtt ctggtgggtg acctttttct
     3001 tgccgatttt aatggccgtt gggatgggga ctgttttctt tatctcgaca aagatgctac
     3061 atgccaatag ttcaagtagt gttattatat ctatggttct gatggcaata gttggtattg
     3121 tttccattgg tatttttaat ggtactttat atagtctggt aatgagtttt ctctggagca
     3181 ataccagttt cggtatccat cgtttcaagg tgaaattaga tactacgtat tgtataaaat
     3241 atgccattct cgcattttta gctttattgc cttttctcgc tgttgctggt tatattatct
     3301 tcgatcaaat attaaatgcg tatgatagtt ctgtatatgc aaatgatgac attgagaatt
     3361 tacagcaatt tatggaaatg caacgtaaaa tgataatcgc gcagttaatc tattattttg
     3421 ggattgctgt tagcaccagt tatttaacgg tgtcgttgcg aaaccatttt atgagcaacc
     3481 tgtcactgaa tgatgggcgt attcgttttc gctcaacttt aacgtaccac ggtatgcttt
     3541 atcgcatgtg tgcgttggtg gtgatatccg ggattacggg cggtctggct tatccactgc
     3601 tgaaaatatg gatgattgac tggcaggcaa aaaatacgta tttgctgggc gatttggatg
     3661 accttccttt aatcaataaa gaagaacaac cagataaagg cttcttagcc agtatttcac
     3721 ggggaattat gccttcttta ccatttctgt aagagataaa aaaggccgga gcatgctccg
     3781 gccttcgttt tcatcactgt gttttgatta cagcgcggcg ataacagcct gctgttcaat
     3841 cagcttcgct ttcgcttctg cataaccttc cagcttctca cgctctttcg cgataaccgc
     3901 ttccggtgcg cgggcgacaa agccttcatt tgccagcttg ttctcgatgc ggctgatttc
     3961 accttcgatc ttcgccactt ctttcgccag gcgcgccagc tcatcttctt tgttgatgag
     4021 gccagccatc gggatcagca gctctgcgcc gtcgatgatc ttggtaacgg aaaccggacc
     4081 tttgtcatcg gcaggcagca cggtgatgct ttccagacgc gccagcgttt gcaggaagcc
     4141 acggttttcg ttcactcgac gttctgcatc cgcgctgcaa ccacgcagca gcagttccag
     4201 cggtttgccc ggcgcgatgt tcatttctgc acggatgtta cgtacagcaa cgatcgcctg
     4261 tttcagccac tcggtgtcgg ccagtgccgc ttcatccacc tgagacgcat cgtactgcgg
     4321 gaacggctgc agcatgatgg tgtcggcagt gataccacaa agtactttca cacgctgcca
     4381 gatggtttcg gtgatgaacg gaatgatcgg atgcgcgagg cgcagcagac cttccagtac
     4441 agtcaccagc gtatggcgag taccgcgcag ttctgcttcg gtgccaccgt tcattaccgg
     4501 cttggtcagc tcgagatacc agtcacagaa ctggttccag gtgaattcat acagaatgcc
     4561 tgcggcgata tcgaagcgga agctgtccag cgcttcgcgg tacgctttga tggtctggtt
     4621 gaactccgcc agaatccagc gatccgccag cgacagcgtc atttcgccgc cgttgaagcc
     4681 gcaatcctga ccttctgtgt tcatcagcac aaagcggctg gcgttccaca gcttgttaca
     4741 gaagttacgg taaccttcca ggcgcttcat atcccagttg atgtcacgac cggtagacgc
     4801 cagcgccgcc agggtgaagc gcagggcatc ggtgccgtgc ggttcaatgc cgttcgggaa
     4861 ctgtttctcg gtgcgcttac ggattttgtc cgccagctgc ggctgcatca tattgccggt
     4921 acgtttttcc agcagttctg gcagcgaaat accgtcaacc atatccagcg ggtcgataac
     4981 gttacccttg gatttggaca ttttctggcc ttcgtcgtca cgaatcagac cggtcatgta
     5041 aacagtgtgg aacggcacct gcggtttgcc attttcatct ttgatgaagt gcatggtcat
     5101 catgatcatg cgggcaatcc agaagaagat gatgtcgaaa ccagatacca tcacgctggt
     5161 tgggtggaac tgacgcaggg cgtcggtatt ttccggccag ccaagggtag agaaggtcca
     5221 cagcgcagaa gagaaccagg tgtcgagaac gtcttcgtcc tgacgcagga caacatcagc
     5281 accgaggtta ttttctttac gcacttcgtc ttcgttgcgg ccaacataaa cgttacccgc
     5341 ttcgtcatac catgccggga tacggtgacc ccaccacaac tgacgagaga tacaccagtc
     5401 ctgaatatcg cgcatccagg agaagtacat gttttcgtac tgcttcggta cgaactgaat
     5461 gtcgccgttc tcaaccgctt caaccgccgg tttcgccagg acatcggcac gcacgtacca
     5521 ctggtcggtc agcatcggtt cgataactac gccgccacgg tcgccgtaag gaacggtcag
     5581 gtcgtgcggt ttaatttctt ccagcaggcc gagtgcgtca accgcagcaa cgaccgcttt
     5641 acgtgcagca aaacgctcca gtttctggaa ttctgccggg atctcgctgg aataaacgtc
     5701 agattcgtta cctttggtat cgaacacctg ggcgctttca cggatatcgc cgtcaaaggt
     5761 aaggatgttg atcatcggca gggcgtgacg tttaccgact tcatagtcgt taaagtcgtg
     5821 cgccggggtg atcttcacgc agccggtgcc tttttccatg tcggcgtgtt cgtcgccaac
     5881 gatcggaata cgacggttaa ccagcggtag aatgacatat ttgccaatca gatctttgta
     5941 acgcggatct tctgggttaa cggccacgcc ggtatcgccc agcagggttt ccggacgggt
     6001 agtcgcaacc accagataat ctttaccatc tgcggttttc gcgccgtcag ccagcggata
     6061 gcggatgtgc cacatcgaac ctttcgattc gcggttttcc acttccaggt cagagatagc
     6121 ggtgcgcagt ttcgggtccc agtttaccag gcgcttgcca cggtaaatca ggtcttcttt
     6181 atacagacga acgaaaactt ctttcaccgc attggacaga ccttcgtcca tggtgaagcg
     6241 ttcacgctcc cagtcgacgg agttgccgag acggcgcatc tgacgggtaa tggtgccgcc
     6301 ggattccgct ttccattccc agattttgtc gatgaaagct tcgcggccgt agtcgtgacg
     6361 ggttttacct tcttctgcgg caatcttgcg ctcaacgacc atctgggtag cgatcccggc
     6421 gtggtcagta ccgacctgcc acagggtgtt tttgccctgc atgcgctgat agcggatcat
     6481 ggtatccatg atggtttgct ggaaggcgtg acccatatgc aaactgccgg tgacgttcgg
     6541 cggcgggatc atgatgcaga aactttcctg gctttcatcg ccattaggct taaagtagcc
     6601 ctgcttttcc cagtgctcgt aaagcggctg ttcgatatct tgtgggttat atgtcttttc
     6661 cattatttcc aggttgccgt attcaggttg aaaccagcca cgcggtaggc tttatagcgt
     6721 tcgcgcgcca gttgtttcag agaatcttca taaggaacga agtctaccac ttctgtgaaa
     6781 gcggtggcaa aatctgcaaa gcttgttcgc agactaatca atatatcgcg cgggctgctg
     6841 ctacgctttt gcggccaggc gatctccacc ggcgcaccgc cgcgcggtcc ttctcccgct
     6901 aaattatgcg gaacaaagct ttctgccgga cgcgcccaca gggcttcatc cagccggtaa
     6961 gcctgctttt catcttcaca ggcgatgagc acgcgcttac cgctgcgcca acgttctgcg
     7021 gcaatttcac acaccaactg ctcaacggcg cttaagccat cgacggtggt gtcattgtcc
     7081 agaaggtaga acgttgcgtt tttcatatat ggggcttctt gtggtggatt taaatgcgca
     7141 tcagatatac accgcagcgc ctgatgcgac gctgccgcgt cttatcaggc ctacgaattc
     7201 gggcagtgtg taggtcagat aaggcgttta cgccgcatcc gacaataaca gccttgcctg
     7261 atgcgacgct gccgcgtctt atcaggccta caagttaagt gctgtgtgta ggtcggataa
     7321 ggcgttcacg ccgcatccga caataacaac tttgcctgat gcaattactc ttcgccgtta
     7381 aacccagcgc ggtttaacag gaactgtgcc agcaacgcta ccgggcgacc ggttgcgcct
     7441 tttgctttac cagaacgcca ggcggtaccg gcgatatcca ggtgcgccca gttgtactta
     7501 cgggtaaagc gcgacaggaa gcaacctgcg gtaatcgccc caccaggacg accgccaatg
     7561 ttcgccatat cggcaaaatt ggactccagc tgttcctgat actcatcacc cagcggtaaa
     7621 cgccatgcgc ggtcaccgga ttgttcagac gccgcaatca gctcatgggc cagcggattg
     7681 tggttcgcca tcagaccggt aatgtgatgg cccagcgcga tcacgcaggc accggtcagc
     7741 gtcgccacgt caatcaccgc ttccggctca aaacgctcaa cgtaagttaa cacgtcgcat
     7801 agtaccagac ggccttcggc gtcggtattc agcacttcta cggtttggcc ggacatggtg
     7861 gttaacacat cacccggacg ataggcacgc ccaccaggca tgttttcgca acctgccagc
     7921 acgccgataa cgttaatcgg cagttgcagc tctgcgacca tacgcatcac gccgtaaacc
     7981 gccgccgcgc cgcacatatc gtacttcatc tcatccatgc cttctgaagg cttgatggag
     8041 ataccgccgg agtcgaaggt taaaccttta cccaccagca cgattgggcg tgcatcttcc
     8101 gacgcgttgc ctttgtactc aatcaccgac atcagcgatt cgttctgcga accctgaccg
     8161 accgccagat aagaatgcat ccccagctct ttcatctgct gttcgccgat aacgcgggtg
     8221 atgacattct tgctgtagct gtcagccagc tggcgcgcct gagaggcgag ataagcggcg
     8281 ttacagatat tcggcggcat attaccgaga tctttcgctg cttttatccc ggcggcaatc
     8341 gccagaccgt gctggatcgc gcgctcaccg ctggtcagtt cacggcgggt cggcacgttg
     8401 aacaccattt tacgcagcgg acgacgcggt tcgctcttgt tcgttttcag ctgatcgaaa
     8461 ctgtagagcg tctcttttgc agtctcgaca gcctgacgca ctttccagta gttgttacgg
     8521 cctttaacgt gcagttcagt cagaaagcag accgcttcca ttgagccagt atcattcagc
     8581 gtattaatgg ttttctgaat aacctgcttg tactgacgct catccagctc acgttctttg
     8641 ccgcaaccaa taaggagaat tcgctcggaa agtacatttg gcacatggtg cagcaacagt
     8701 gtctgccccg gttttccttc cagttcaccc cgacgtagca gggcgctgat gtacccatcg
     8761 ctgattttat cgagctgttc tgcaatcgga gaaaggcgac gtggttcgaa gacgcccacg
     8821 acgatgcagg cactccgctg tttctccggg ctaccgcttt ttacactaaa ctccatgcac
     8881 tacgctcctg aatcttaaag acaacggcgg tggctacaga tagaattgca agctttcgta
     8941 actcatgtcc gctgttgcga tgacttcgtg ttaatcttaa cgttattacg gcattggcac
     9001 gtcagaacat aatctgagag gtgaatccgt tgagtataat tatcttagcg acgatttcga
     9061 cgactcaaga gaataaatga cgtttaagcc atgaaacaag ctaaaatcct gcaaaagacg
     9121 agtttttacg ggcgtattta aagtgataat cataagatat ctggtgcggg agacgctcaa
     9181 aagccagctg gcgatactct tcatcttgct tttgatcttc ttctgtcaaa agttagtgag
     9241 gatcctcggc gcagcggttg acggcgatat tccggcgaat ctggtgctct cccttctcgg
     9301 gttgggcgtg ccggaaatgg cgcagcttat cctgccatta agcctgttcc tcgggctgct
     9361 gatgacgctg ggcaaactgt ataccgaaag tgaaattacg gtaatgcatg cctgcggcct
     9421 gagcaaagcg gttctggtga aagcggcaat gatccttgcg gtattcacgg caatcgtcgc
     9481 ggcggttaac gtgatgtggg cgggaccgtg gtcatcgcgt catcaggatg aagtgttagc
     9541 agaagcgaaa gcgaaccctg gcatggcggc gctggcgcaa gggcaattcc agcaagcgac
     9601 taatggcagt tcggtgctgt tcatcgaaag cgttgacggc agcgatttca aagatgtgtt
     9661 cctcgcgcaa attcgaccaa aaggtaatgc acgtccttct gtggtggtgg ccgattccgg
     9721 acatttaacc cagctgcgcg acggctccca ggtcgtcact ctcaaccagg gaacgcgctt
     9781 cgaaggcact gcactgttac gtgatttccg cattacggat ttccaggatt atcaggcgat
     9841 cattggtcac caggcggtgg tgctcgaccc gaacgatacc gaccagatgg acatgcgcac
     9901 attgtggaac actgacaccg atcgtgctcg cgcagaactg aactggcgta tcacgttggt
     9961 attcaccgtg tttatgatgg cacttatggt cgtaccgctg agcgtggtta acccacgtca
    10021 gggacgcgta ctgtcgatgc tgccagccat gctgctgtat ctgttgttct tcctgatcca
    10081 gacctccctg aaatcgaacg gcggtaaagg taagctggac ccgacgctgt ggatgtggac
    10141 cgttaacctg atttatctgg ctttggcgat tgttctcaac ctttgggaca ccgtgccggt
    10201 ccgccgcctg cgcgccagtt tttcgcgtaa aggagcggtg tgatgcaacc ttttggcgta
    10261 cttgaccgct atatcggtaa aactattttc accaccatca tgatgacact gttcatgctg
    10321 gtgtcgctgt cgggcattat caaatttgtc gatcagttga aaaaagccgg gcaggggagt
    10381 tacgacgcgt taggcgcagg aatgtatacc ttgctgagcg tgccgaaaga tgtgcagatc
    10441 ttcttcccga tggcggctct gcttggggcg ttgcttggtc ttgggatgct ggcgcagcgc
    10501 agcgaactgg tggtgatgca ggcttctggt tttacccgta tgcaggtggc gctgtcggtg
    10561 atgaaaaccg ccattccgct ggtcttactg acgatggcga ttggtgaatg ggtcgcgccg
    10621 cagggcgagc agatggcgcg taactaccgt gcgcaggcga tgtacggcgg ctcgttgctc
    10681 tctacccagc aaggtttatg ggcgaaagat ggcaacaact tcgtctacat tgagcgggtt
    10741 aaaggtgacg aagagttagg tggcatcagt atttatgcct ttaacgagaa tcgtcgtctg
    10801 caatccgtac gctatgccgc taccgcgaag tttgacccgg aacataaagt ctggcgtctg
    10861 tcgcaggttg atgaatctga tctgaccaat ccgaaacaga tcaccggttc gcagacggtg
    10921 agcggcacct ggaaaaccaa cctcacgccg gacaaactgg gcgtggtggc gctggacccg
    10981 gatgcactct ccatcagtgg tttgcacaac tacgtgaagt atctgaagtc gagcggtcag
    11041 gatgccgggc gttatcagct caacatgtgg agcaaaatct tccagccgct atccgtggcg
    11101 gtgatgatgc tgatggcgct gtcgttcatc tttggcccac tgcgtagcgt accgatgggt
    11161 gtgcgtgtgg tcaccggtat tagcttcggt tttgtcttct acgtactgga ccagatcttc
    11221 ggcccgctga cgttggttta tggcatcccg ccgatcatcg gcgcactgtt gccaagcgct
    11281 agcttcttct taatcagcct gtggctgtta atgagaaaat cgtaaccgaa tgaacgaata
    11341 aagggagcga aagctccctt tattattgtt agcatagtgt gcttcgttca tttatgaaaa
    11401 atcattaaaa ttcaatatat tgcagtggtg tgggcataat aagacgcgcc agcgtcgcat
    11461 caggcaaaga caaatcgcac ctggcttacc tttttctccc ccccagcaaa ctccccaaca
    11521 ttccacgcac aatctgattc gtcacctggc gggcggcgct tttcgccatt gtttgcacaa
    11581 caccatcttt cttcccgccg cgtggtccgg tagtgccgaa caaaatatcc ttcaatccac
    11641 caagaatgcc gtcatctacc gctacctctt tccctttcgc ggggggatta ttttgctgct
    11701 cggtgcttgc ctgtacgcct ttttgcaaca tctcataggc ggattcccgg tccacgtcat
    11761 cctcgtactt gccatacacc ggagagtgat taatcaagcc attacgctca tcttccgtca
    11821 ccggtcccat ccgcgaacaa ggcgcaatca ccatcgcccg ttccaccaca gaaggacttc
    11881 cttttgcatc gagaaacgag attaacgcct cgccggtccc cagttcctgg attgcctttt
    11941 ccgtatcaaa tgcaggggtg gggcgcatgg tttgcgccgc agcttttacc gctttctgat
    12001 ctttgggcgt aaaagcacgc aaagcgtgtt gaacgcgatt accgagctgg ccgagcacat
    12061 tatctggaat atcagacggg ttttgcgaaa cgaaccagac gcccacgcct tttgagcgaa
    12121 taagccttat cacctgctca atcttatcca gcagtacctg cggggcatcg ttaaatagca
    12181 gatgtgcctc gtcgaagaaa aacaccagtt ttggtttctc cagatcgccc gcttccggca
    12241 attgttcata caactctgaa agcatccaca gcaggctggc ggcgtacagt ttcggcatct
    12301 gataaagttt ctcggcgctg aggatattga taacgccttt accgttggca tcggtgcgca
    12361 tccagtcttt gatatccagc atcggctcac caaagaagtg tgctgcgcct tgctgttcca
    12421 gcgacaacag cccgcgctgg atggcaccaa ccgatgcgct actgatattt ccgtactgat
    12481 tctggaagga tttggcgtta tcgccgatgt actgggtaat tgcccgcaga tctttaaagt
    12541 cgagcagtaa cagcccctga tcgtcagcaa tgcggaaaat gatatccagc acgccagatt
    12601 gcacatcgtt gagattcaac agtcgcgcca gcaacagcgg tcccagatcc gaaaccgtcg
    12661 cccgcaccgg atggcctttc tcgccaaaga tatcccacac caccaccgga ttggcatgcg
    12721 gttgccaatc attgacgccg atatttttaa gccttgcgag cagtttttcc gacgccgttc
    12781 ctgcctgcgc gataccggtc agatcgcctt tcacatcagc cataaacacc ggcacgccga
    12841 tttccgacaa tgactctgcc agtttttgca gcgtaacggt tttacccgtc cccgttgcgc
    12901 cggtaatcag cccgtgacgg ttcgccattc ccggcagtaa aaacagttct gtgtccggcg
    12961 tgcgggcaat taacaggggt tcgctcatga gatttcctcc agtttcctgc ctggagtata
    13021 ggcaacggct gcgcactctt caccgctaaa ttcagcagat tgcgagacgc cttccaaaga
    13081 gatttaagtg ccgggcgaca ggcacccggc aaagggatca gaagtcggct ttcaggacca
    13141 ctcggtagcg cgctttacca tcgcgtacat gctgaatggc gtcgttaatt ttcgacatcg
    13201 ggaacaattc ggtagtcggc gcaaccttgc tgcgggcggc aaagcgcatc agcttacgca
    13261 actcataagg cgtgccggta gcagaaccag agacgctgcg gtcgcccgca attaacgtaa
    13321 aggccggaac agacagcggc gtgagaaccg caccgaccgt atggaaatta ccgccgtacg
    13381 tcagcgcttc aaaataaggc tgccagtcga ggttgacgtt gacggtgttg ataatgagat
    13441 caaactgccc cgccagtgct ttcagtgcct gcggatcgcg gctattcacc actttatcgg
    13501 cacccatcgc cagtacttcc tgctctttcg ccggattcga actaaaggct gtcacctcgc
    13561 atcccattgc gtgcagaagt tttatagcga tatgccccag cccgccaata ccaattaccc
    13621 caacgcggct ggtggcagtg atatggtgca ttaacagtgg tttgaagacc gtgataccac
    13681 cgcacaacag cggcccggcg gactcgatat caatattttc tggcagtgga atcacccatt
    13741 gccagtccgc acgcaacttc tcggcaaagc caccgcgatt cataatcgtc ggcaccgcac
    13801 cttgctcaca gttgatctga ttaccgctaa tacaggcatc gcaatgcccg cagctacgcg
    13861 ccgtccagcc aatcccgaca cgctgaccga cctgcaaacc tttatcctgc gcggcgctcc
    13921 cgagcgccac cacgcgacca atcacctcat gcccggcaac cagcggatat tgtgaaaatc
    13981 cccattcgtt atcgatcatc gacagatcgg aatggcagat cccgcagtaa tccacctgca
    14041 cttcaacatc ttgtggcttc agttcaccgg gatcgtactc ataaacttcc agttcgccgc
    14101 ctgcttcttt tgcggcatag ctttttatca tcgacatttt ttggtccttc tctggtgttg
    14161 tctgggaagt gtagagcatg gcagggcggg gtgcctggag tgtgacaaag gttacacatc
    14221 gctgtatgca atgctgaaaa tttcagcact tagcgaggtg cgagcaagct ggcgcttgca
    14281 tggtggcgtg cgacaggtat aatccacaac gttttccgca tacctcttca gtgccgaagt
    14341 ggcgaaatcg gtagacgcag ttgattcaaa atcaaccgta gaaatacgtg ccggttcgag
    14401 tccggccttc ggcaccaagt cactaaattc cttacaatac aggtagttag acaataaaat
    14461 ctgtctcttt tgcctgtaag aaatgctctg ttatgtccct tgaaaaagcc gctgtggttg
    14521 atagtggtaa ttgggatgtt aactcatagc ggcgtgtagt tccaagcgtc aaacacgtac
    14581 tgactcaact tgaaagctat gacgtagcca ctgtctctaa acaatcccaa aaacttttag
    14641 tgaagcgcat tttagcccga tgcccccgtt ctgccgctgt cgcgagacgc cgcaggggat
    14701 aaacaggttt atggtggtca cggtacttgc agaccatatg caagctctgc cagcggttcg
    14761 gcctcgctcc ccttgggtac atggtcatcc tgataagcct cactaactga cataactgtg
    14821 atgtagtcgc cagaggctcc gcttgttgtc ttaccaccaa cggggcttta tggattctat
    14881 tgcggtatgt ttgaaagtgc gcgggggttc attcccgcgc gtccggcgct ttatggtaag
    14941 tatttaagta tttctgctgc ccagtttaca cggtggatga cacgggcatg gtgcaagttt
    15001 ccgtctagta tttcggcttt agttagctgg gataactgct gccaattatt gttaagtata
    15061 taagttgcgt tattacattg tgagctttct agcacgtaaa tgttttggcc tgtgaaccca
    15121 aatatcacgt agccttggaa cccagcttgc ccaaccgcta cgaaatctgg ttttttacta
    15181 ttgataagtt caagtctgcc ttcaacaaca gcggtattgc cctttcccct gatcttaata
    15241 gctgaaagga tttttgagcc gatagtactc caaggctgtt gaccctgagg caggaggctc
    15301 cagtttagtt ttatagattt acttttaacg atggtattaa gttggtcgtc aacagtttcg
    15361 cacaacccaa aaagctctaa aaaaagatta atgcagtgag ccactaactc tttgttgtta
    15421 gctgtcaaac ttagctttgg agagatgatc aacttctccc cttgaagatt ctctacaatc
    15481 tttaactcta tgcttggtgg aggggtgagg attctcttgt agcgcttata ctcaatttca
    15541 cgagtgtcag taacttcttg agttgcgccc cctccgatcc attgctttct agtccatgaa
    15601 atttgtctgt atgcagtttc tttaggtgct gttttgtcag gtactgattt gccattagca
    15661 ttgaatctgg ttattggccc taaaatcttg gggaggactt cttcacctaa agctctttga
    15721 cttgagaaac caatagagtc cgttttcccc gcatctggca aagaatgtgc aatgtagata
    15781 tcacggccat caaagttagg tatgtaatta tcaatatttc gaatacgctt tttctgaata
    15841 agcatggatc gttccttttg attttatctt actgtttaca taaccaacca agccgggcac
    15901 aatcgagccg ttagaaacga tagtgaggct aacaatcgtt atgagtttgc agactcatgg
    15961 cggtcatgct tcatagaccg gattcacgca ggtgactccg gtttttttat gcccatcatt
    16021 tatacatgag cacaacatat agggtgtgtt aataagatta ccccctacat gttcagcatt
    16081 ctagttagga ttctttgcag tacaagggtt gattttgagg ttaaattgag gttgtcaaag
    16141 ggaaatttcg accaacccta cgtgccgtaa ggcttaggct gtatgtcaat gtttcagaaa
    16201 aaaaatgaaa atttgatcga gtgctgattt ctttagcacg agaacatgag atcgaaccaa
    16261 aatattgcaa agttttgaac aaaacttgag ctgcctcgtg tctccatagc caagacgaat
    16321 gcagtttaaa taagctaagt cagctctcaa aagtccttta tgacccgaac caaaaattgt
    16381 acctcttaaa cccccaccgc aagcggctct ccggggtttg tgcgcgtgga gtaatgcgat
    16441 tgtactgggt atgtgcgcac aaccctctac aagccgcatt ctaccgttag cctatagctg
    16501 aatccccggc ttgaaaaatt gcacgcttat ggttgcccct ccctcaactg tatagctcgc
    16561 ccgcgccccc gtgcgcatgt gcgtgcccgc gcgtcagggg tcgctgagaa aaccctaaga
    16621 ttttgctcat ccgagacaac cgttgcaggc gcgcgttgcc ggggcacact gttagtgttt
    16681 gatggtgtca tcaatcgacc gttttctggc acctcccaat cgcacgcttt cacactgttg
    16741 gaaaaatagc cttggctttt ctggcaggcc atcctaatgt tggcctcgtt ttctggcagg
    16801 ggtcagatgg ggagataaca atggcaactt ttggctacgg acgtgtttcg acatcgcagc
    16861 aggatactga gaaccaacgg ctggagcttg ggcaggctgg gtggcaaatt gattactggt
    16921 ttgccgatgt tgttagcggg aaggttccgg caatgcaacg taaagcattt tctgaaatgc
    16981 tcaataaaat ccgcgatggt gaaacgttgg tggtagcgaa gcttgatcgt ctggggcgtg
    17041 atgcgattga cgtcctgcaa acggtaaggg cgctggctga ccgtaatatc aaggttcttg
    17101 tccaccagct tggtaacaca gatctcactt ctgccgctgg gaagttgcta ttatctatgc
    17161 tcgccgcggt tgcggagatg gagcgtgatc tgctgattga gcgcactcag gcgggactat
    17221 cacgagcaaa agccgaaggt aagaaattgg gcagacctcc taaaatcgcg tcagaagccc
    17281 gtagagagat tttagagaaa aagaatagcg gtttgagtat cagtgcgtta gcgcgtcaat
    17341 atggcgtttc aagagcgact gtagcagcta ttaccgattg aatatggaga gtttatggct
    17401 tacacagcaa ctgttatccc tgtaatgatt gcttctcctg gtgatgtcgc tgaagagaga
    17461 caagtcattc gtgaaatgat ccatgagtgg aatgatataa attcagctcg ttcaaaagta
    17521 atgttgacac caattggatg ggaaactcat acatcacccg aattaggagt taggcctcag
    17581 aagttgatta atcaaagatt attagtagat tgtgatttat taatcggtgt gttttggact
    17641 cgtctaggct caccgactgg gaacgaggcc agcggaacag tcgaagaaat ccaccgtcat
    17701 ttgaatgcgg gaaaaccggc aatgatttac ttttcctcaa agcctgttgc ccctgaaagc
    17761 cttgatagag aacaatatga gtctcttaaa ttgttcaaaa ctgagtgcat gcaaaaggga
    17821 ttgatagagt cttttaatga cttatctgat ttcaaagaca aagtccgtag gcaactttcg
    17881 ataattattt ctagtagccc ttatttgtct tctcttatat ctaccattaa caattctcct
    17941 gatgcgaata caagtcaatc tttgccagaa agtaatttgt ccgccgatgc actcagtttg
    18001 ctgaaattgg catgtgtcga tgatagcgga acaatttatg tgataaggca tttaggtggc
    18061 acggatattc aagcgggaaa tcaatccttt ggtggaagtt cggctagaga ggtagcccgt
    18121 tgggagggcg cacttaacga actgttatcc tttgattatg tgattgaaag aggggcaaaa
    18181 ggacaaatgt attatgttac tcataaaggc tggacatttc ttgaatcttt aaatgaataa
    18241 ttaaatgcga ggccattaca taagtttatt tttgatgtga gggtgaattc cctcacattt
    18301 ttattcgaaa gaggccgcaa tgacttctcc tgtttttgcg ttgaaaacac aaaagtattg
    18361 aagcggagct agcatcccca agccgttaac taccttagct tgttgcccaa atgcctgaat
    18421 aatcttcgca ttctcatcgt gccagagata agtattaaat acaggcgctt cgctttcttg
    18481 ccacacatgg cgaaacttcg ctttctcatc cattaccttt ttgcactccc tgaccgggtt
    18541 atggtgcgtt ttcgcatagc attccgggtt gtcatctgca catacgatat cttttcgtgc
    18601 tgtctgatgc tcagcaccta cagcagaaaa ggcgcatacg cccagcacca atgagagagt
    18661 gcccagagca ccccatacag ttgcgcgtag cgtgctgatg tgctgctttg atacagcatg
    18721 ggcaactaca ctataactgg cccagctaat cgcggctccc gctgcaatcg gtagtaaaaa
    18781 gtctgctccc gtcatgattc cctcactttc caaaccacat cgcgcctgat agcgaacgct
    18841 ggtgacgccc aaccgatgat gatcatcata cttgttgggt tttaaatgtc accattggtg
    18901 tttgttttga atcaaaaagg attgtcatga tacagccgat gaatgctagt gactaagctc
    18961 gctgacgtga gattggattc aaaatatctc atatggagcg tggccttaca gtggtcaaaa
    19021 ttgcacattc agtgcatgaa aaaatccctg agaatacagt ttggcgagcg ggtaaaagaa
    19081 ctgcgcattg ccaccggatt gagccaggag gcctttgccg atcggtgcgg gtttgcacgt
    19141 agttatatga gcagaattga acgtggtggc tctaatgcgt ctctggatgc gattgaggtg
    19201 ctggctaacg ctctgagcgt tgagccgtgg cagttgttag cgcctggccc atctgaagat
    19261 aacgactcgg aactgttggt tccatacgca gccgatggtt cctgttttca ccccggtttg
    19321 gcgagcaccc gtgatggctc gtttggcgta ggtgataaag cggctcagaa gcgttttggc
    19381 acgtttgctg aagctcttga gtatcttcgt agcatggaga cagcaaaatg gcgtaggcct
    19441 aatcctagcg gcaactgggg tatcgtatca gcggttcggt gggacaaact gagaaagtag
    19501 ctcaagtgta agtttatgaa ttttcatgct gtatggatga acagtattca ttagatgctg
    19561 atagtcttat gtttcatcag ccctttgttt ctataagagt gaataaaaca gcaaaatgcg
    19621 ggtgcgttac gtaggcgtta cggtggcgtt tcgctttggc tcttaatggc ttaattcata
    19681 taaataacat tgagttaaat agttattctg aacaaggtct gccggggtct aactggtttc
    19741 aaaatccgaa cgcagtggcg tttattcaac gtccacatag ctgacaaatg ttctttcctc
    19801 ccgactcggc agacctccag aaacattaaa aggcaggtat ggcacgttga tgttttatgc
    19861 cgccacgaac actcggtttg attccgtcca gcggatcaaa cttaatatgt agcccctaga
    19921 acaaaaaggt cctacgattg ctctcttaac agctaacagg aacgtgatta cagcaggtta
    19981 tagagactta ggttcgagtc cggccttcgg caccaaaagt atgtaaatag acctcaactg
    20041 aggtcttttt ttatgcctga aatccagtgt ttatctatct ttcccgctat attaactctc
    20101 tcaaggtcaa ccgatatcaa cgtacatcta ccaacatatg ttggtacaga tgatggtatt
    20161 tccggttcga taatgcttgt accaacaggg agggaatacg catggcatta acagatatca
    20221 aagtcagagc agccaagcca acggataagc aatataagct gactgatggt ggcggtatgc
    20281 atctgcttgt ccatccaaat ggttctaagt actggcgttt gcagtaccgt tatgagggaa
    20341 agcaaaaaat gctggcactt ggggtttatc ctgaaatcac actagcggat gccagagtac
    20401 gtcgtgacga ggcgcgtaag ctgcttgcga atggcgtcga tccgggagac aaaaagaaaa
    20461 atgataaggt tgaacagagt aaagcacgaa cctttaaaga agtcgcgatt gagtggcatg
    20521 gcaccaataa aaagtggtct gaagatcacg cccatcgtgt gctaaaaagt cttgaagata
    20581 atctttttgc agcgcttggt gaacgtaata tcgctgagtt aaaaactcga gatttattag
    20641 cacctattgt tcctttaacc atccgcaatg gccaacggtt tacagagcat aatacgaata
    20701 gccgtagagc cagccagtta cggtggtcgc gatggtgtgt ccgccagaaa atcaccacga
    20761 ataccagaat cgcggcactg accagaaaat gataaacagg aaacacgggg aggttcactt
    20821 tgctttctcc tgtagtattt tctgtaggtt ctgaaccggt tcgagcgggg ttgtgaggct
    20881 gatggcaatc cccgggctct tcctgcatgt tacactggta ctgcaacagg gggccttcgc
    20941 tcctatgaca ttactcagta ttttcactac tacaccccat ctgccatcca taacaaccga
    21001 ttcaccccct cgggaggcgt tgttgcccgt cacccggaca ggcatcgtta tggacttctc
    21061 ttgttgcacg atcgatcaat tgttatgcat gctgacacca ctaccccggt gggtatgacc
    21121 gatgcctttc tcactctctt cccggtcatc gtcggccttc cccgttattg tggcgtgtcg
    21181 gcaccatcga cggcatttcg atggctgctc agtgttcact cacgttacgg cccgcataac
    21241 ccattgactt cctgaagaag tcgtttcagg gagagattca gcccttttgt tacctcctgg
    21301 accgcttcct gtccttccag ttggagcgag agttagtcgg ggcggacttt caccgacgga
    21361 aagatcgtgc atttcaaggc acacacaaca atatctgcga gcgtgctatc cgtccggtcg
    21421 ttatgggacg aaaggcctgg ttgttcgctg gttcactgat ggccgggaac cgagcggcac
    21481 agataatgag ccttctggaa acagcagtct ggagccacat gcttggctga cggacgtcct
    21541 aacgcgtctg cccggagtgg ccggaggaga ggttggcaga gttactgcct cttgagggct
    21601 ttaccttctt tgggtaagtg atacctgccg tcaggtgttt gtgcaccggg ccataacctg
    21661 cagttgggaa ttgaacgcct gacaacagga aatgagctag agcagtaaac acgcgggctg
    21721 acaatgggtc agaatatgag tctgcccggc gttattcttg gggtcagtac ttcagatcca
    21781 gcctccggta ccagactagc tagcccctac gcaaccaaat aaatcaacca tcgtaagagt
    21841 gcaatcgttc atatacactg ccggtgatgg gcggaaaaat gcgttaatgt tgagttcctc
    21901 gaacccttac caattaaggg acatagccag atacgcaact ggctgatgca agcagtctga
    21961 tgtctttaga ttcgctggcc tgcgggcatg acaatgtcaa acagtcaaag attgtggcgt
    22021 tgacggtcag tctgggtcgt aaaaacttcc tgttcttcgg ctctgaccat ggtggtgagc
    22081 ggggagcgct actgtacagc ctgatcggga cgtgcaaact gaatgacgtg gatccagaaa
    22141 gctaccttcg ccatgtgctt ggcgtcatag cagactggcc ggtcaaccgg gtcagcgaac
    22201 tgcttccgtg gcgtatagca ctgccagctg aataacacat ccccgtcaat acggccctcg
    22261 ctgtacgctt acgattagtg gtggtgtctt ccagtgcgag gagcagcgga tgagcctcac
    22321 atgcccttgc agtggcggta aatccggctt aggcaatggc ttccggggac acagacgggt
    22381 tacgtatcag gcggtacgca ctttcaacct gagcagtgga gtgggatgat ttcacaatag
    22441 aaagacctgc atgctgagcg agagaagagg ccagtgacac aaggcgtcgt gtacgacgcg
    22501 gatcaccgag acgggcatgt ccaaactgct cgttatccca tgaataacaa tcagaaagta
    22561 ccataacaga cccgaagaaa atgaaatata agagaagatc aacgggtgaa gaaaaagttc
    22621 aaaaaatcgc tgccggggag gaaggaaact accgaatgga aagagtcccc ctaaagcaga
    22681 ctgacaaaca tcacaaatcc ccgggtgggg atttgtgtat aagagacagc ctgatagggg
    22741 ggcgcataca ttatgcatac atactctcgg atattgtaaa agttttttat ataattacta
    22801 agttagctac catcaataaa atattgacgt tagcaggtaa catcaactta atatataaaa
    22861 atattcttag gtgaaagtaa ctgttcaaga taaaataaaa tcatcgctta aaaagaa
//
LOCUS       DADXDL010000074        22866 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.074, whole genome shotgun sequence.
ACCESSION   DADXDL010000074 DADXDL010000000
VERSION     DADXDL010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22866)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22866)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22866
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.074"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..232
                     /locus_tag="IRB70_003409"
     CDS             <1..232
                     /locus_tag="IRB70_003409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="Tn3 family transposase"
                     /protein_id="HBC0633277.1"
                     /translation="LVTNAVVLWNTIYMQAALDHLRAQGETLNDEDIARLSPLCHGHI
                     NMLGHYSFTLAELVTKGHLRPLKEASEAENVA"
     gene            complement(1208..1393)
                     /locus_tag="IRB70_003410"
     CDS             complement(1208..1393)
                     /locus_tag="IRB70_003410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633278.1"
                     /translation="MDRKSNSDSYQRWMIEKADKRERTQISMSFVKMKDVLFNVLAIG
                     TVLAALVVIFYEVQSSL"
     gene            complement(1351..1563)
                     /locus_tag="IRB70_003411"
     CDS             complement(1351..1563)
                     /locus_tag="IRB70_003411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004221700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633279.1"
                     /translation="MVTQSLADFGRYSYKPRPAFQDWIERLKTGERLPRGRYFVGKKP
                     GGRLVLIDELGGTWTEKVTVIHTNAG"
     gene            complement(1626..1901)
                     /locus_tag="IRB70_003412"
     CDS             complement(1626..1901)
                     /locus_tag="IRB70_003412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633280.1"
                     /translation="MHTTNAIILCLVSYPCIVAWVIYKNRFVDYLFLTLLACLGSIFS
                     VVLYKQPDYSLTIYQAVAVGYAAVIMPTVLVLSVVNIFMGKAERTCK"
     gene            complement(1919..2173)
                     /locus_tag="IRB70_003413"
     CDS             complement(1919..2173)
                     /locus_tag="IRB70_003413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000510385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633281.1"
                     /translation="MGHYTIRTNDDEDQAIKKAQEATGQASASKTFMTAILELQRNRD
                     EMAQLRRELAQEKARSQELVSSVKQFRSSLNNLFDLADNP"
     gene            complement(2283..3104)
                     /locus_tag="IRB70_003414"
     CDS             complement(2283..3104)
                     /locus_tag="IRB70_003414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000196235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT-like domain-containing protein"
                     /protein_id="HBC0633282.1"
                     /translation="MTRATERAYSELQQAFDFYNQRLFDGELPDCLITFQRGKNTMGY
                     FSYRRFVAADGSGRMIDEIALNPEYFPVYPLIEVMQTLVHEQCHMWQYHYGNPSRKTY
                     HNAQWAAKMESIGLMPSSTGRPGGAKVGQKINDYPIPGGRFQRVTLELFQGQFALSWF
                     DRFPVQVEQQKDMTAVIEQWRETLALAHQNAEAGIDIEAVLSMALLPSVSPQNGSHSD
                     DMAGSNDNDLSVAAFEDKPKRNKVKYQCRGCGAAVWGKAGLNIECGDCELAFIEN"
     gene            complement(3101..3280)
                     /locus_tag="IRB70_003415"
     CDS             complement(3101..3280)
                     /locus_tag="IRB70_003415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000136657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633283.1"
                     /translation="MTEKITDEELVDLLEALKRAHGMGVCSKAVKLAQRCADVFPAIV
                     AELQEYRNAAKRTSA"
     gene            complement(3297..3563)
                     /locus_tag="IRB70_003416"
     CDS             complement(3297..3563)
                     /locus_tag="IRB70_003416"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633284.1"
                     /translation="MISIAFASYILLALVVHLTLKQASYNGKVSSPAVNHACQQTSFL
                     QPVWPLIFASNITRSMPALGVKLPAKKIAAIKGVVYIICIVRYR"
     gene            3553..4203
                     /locus_tag="IRB70_003417"
     CDS             3553..4203
                     /locus_tag="IRB70_003417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004242661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
                     /protein_id="HBC0633285.1"
                     /translation="MDIKPNSVIHLEPGETLPGYTNLKPVPDKYFDELKALINKLNTQ
                     SGNIYLKLKQMYAFLDRFNKEFVSTFTSCQKGCSSCCKMDVHLTALEATHIAQASKLT
                     ARDNPLTTGHESKCPFLSEKGTCSIYNYRPLLCRTYHVLTPPEMCNDLDAQVMQYGSQ
                     SANMGNHIYKTIAEWIYFQTYHCTGKLETKDIRDYFPYPREDIQRFLHHNPPRPFC"
     gene            complement(4241..4696)
                     /locus_tag="IRB70_003418"
     CDS             complement(4241..4696)
                     /locus_tag="IRB70_003418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="H-NS histone family protein"
                     /protein_id="HBC0633286.1"
                     /translation="MSENETFDATKKLLLNIRSVRVFARETSFEQLLEMQEKLNAVIE
                     ERREEAEREAAERAERERKRQELLQLIAGEGFSPEELLGLSEDAQKTRKKTLPKAPPK
                     YQFDENGETKYWSGRGRTPKPIDEALKAGRSLDEFLIKKDASSTAGDEQ"
     gene            complement(4708..7035)
                     /gene="topB"
                     /locus_tag="IRB70_003419"
     CDS             complement(4708..7035)
                     /gene="topB"
                     /locus_tag="IRB70_003419"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBC0633287.1"
                     /translation="MRLFIAEKPSLAKAIFEGLGGNPNTEKKNGYFEHGSDVVTWCYG
                     HMLELYDPQDYDDKYSNWRYSDLPIKAVYPPKYKIKPESEAQTRIILSLIDKADSIVH
                     SGDPDDEGCLLVDEILGYAGNKKPVQRLLVADLNLAPVQKSLSNLQPNDKFRGMTLSA
                     LARSLCDQGFGYNMTRGCTLKGREKGYDGVLNVGRVQSAVLGLVNMRTLANQNHTESF
                     YYDVFASLSMNGHQIKAKYQTTDDDQIDEKKRLISEAQAAHIAGRVTGKDAIVTIATT
                     KPENSKPPLPLNLSTLQQLCAKRFGYSAKDTLDVMQGLYETHKLLTYPRSDNRYLSDE
                     HYYQAGDIATAIAATVPELASAIVDMDKGQKHKAFNASKIEAHHAIIPTTKSGAGIQL
                     NEKERNVYNLVSVYFIGLFYPDAIRNKTKIHFDIKGDTFTATQSVLVQKGWEALGKDS
                     DDEDETEDAGTDGFDLSLLKFNDSGLCESADVDKKKTTPPRYFTESTLLAAMTSAAKF
                     IDDPALRKALEAKDEGSSDRGSIGTEATRAGILEKLAANTGLISIEKEKGYSELVWKT
                     TKQGQEFCAALPPEITKPDISALWAEKQSQIKAGELTVEEFIKENDEYVQGLIDELDR
                     NGISISSNATPCPVCNNGFLRKRKGQNGFFWGCSCYPECKTTFPDKDGKPDMEAKSRS
                     EGSMSRLEAPCPSCSKEIIIRPKGFFCSGCEFKIWSEVSGKKLTQNQVETLIKKGKTG
                     EIKGFTSNKTGKKFDAAIVLQDKTTGKLGFQFSKK"
     gene            complement(7039..8301)
                     /locus_tag="IRB70_003420"
     CDS             complement(7039..8301)
                     /locus_tag="IRB70_003420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000517490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBC0633288.1"
                     /translation="MGKLTLVEQALRLHKEYYGEDNFGTVVKDCDYYPKVAEIFINRK
                     NRKIYSNLDIEPVASTVVHTGSSPVMAKAGRIKKLMFKDGSGAYRIHLGQNEVVHIIR
                     FILNSKVRMEYAVGTTKSMSMLHNLCEAGRAKLNRSLPRKGIWKIGCYDGVYYHGKAR
                     KEEIENALRFSVHPKFNELENDFNQFFSDIDFYTRYGQSGMRKVLFTGPPGTGKTTIA
                     KALGAKYQDKYVFVYADDYFKDVCYAAAQKKIPVIIIAEEVDELYRADAGTLSFLDGA
                     DTPRNLAGTYVIFSTNYPNRIDPRIRKRPGRIDRIISVGAFRTKAAAACAKMYLPDDI
                     NIDLKELGAVLDRTTPAEIKEIINIAIGMIRGTKNELTVDVIKNARAFLKGTLDLSVQ
                     EAEEDIEEREEIFKKNGAQPDYSSYLED"
     gene            complement(8384..8878)
                     /locus_tag="IRB70_003421"
     CDS             complement(8384..8878)
                     /locus_tag="IRB70_003421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001215543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thermonuclease family protein"
                     /protein_id="HBC0633289.1"
                     /translation="MRHFFNVLSFAVALLPATLCAAQIQGKVIRVLDGDTIEVKTLPA
                     KIVVYEVPIRVRLINIDAPEKKQPFGRWSTNQLKALLAGQSVTVSYTQTDRYGRVLGR
                     VVTANGTEANRQQVLKGAAWVYDRYNTDNSLPALQREAQTQKRGLWADSNPVPPWEWR
                     HKQN"
     gene            complement(8875..9201)
                     /locus_tag="IRB70_003422"
     CDS             complement(8875..9201)
                     /locus_tag="IRB70_003422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004208538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633290.1"
                     /translation="MKIINVPDARSVRIAGIEIIDSVKSVASVFTEILLFMVWFPAIV
                     YGLYRFVIVLWDASLKPQSLIEFINFMVELYSYVLPSLAVIAVALVVVLSIFKRLSAI
                     WEGRKQ"
     gene            complement(9287..9601)
                     /locus_tag="IRB70_003423"
     CDS             complement(9287..9601)
                     /locus_tag="IRB70_003423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000754496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633291.1"
                     /translation="MKKTVTTAVLLCAFAAGTAHAEEKADPNDPCAMVLCLAGKLDGS
                     SPAECDPMYKSFMSIRKKNKHGFLPDHTADARKKKLNECPAADAGTVSKIISSFGRLK
                     NF"
     gene            complement(9689..10081)
                     /locus_tag="IRB70_003424"
     CDS             complement(9689..10081)
                     /locus_tag="IRB70_003424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000738524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBC0633292.1"
                     /translation="MKKMLMVSVLFLSACSSPPEPPQVDWEQNPETVNTQLMDWQPTY
                     SVIKSDKVNSSWVKVIHNFRPENRLYDDAVFYSVAHSDSVIVETSNGTDFFTAKNWLR
                     ANGANGVIQYRYKMNCFSCRTTSVYLSR"
     gene            complement(10078..11913)
                     /locus_tag="IRB70_003425"
     CDS             complement(10078..11913)
                     /locus_tag="IRB70_003425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000053816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBC0633293.1"
                     /translation="MSLKLPDKGQWAFIGLVMCLVTYYTGSVAVYFLNGKTPLYIWKN
                     FDSMLLWRIITESNIRTDIRLTAIPSLLSGMVSSLIVPVFIIWQLNKTDVALYGDAKF
                     ASDNDLRKSKLLKWEKENDTDILVGAYKGKYLWYTAPDFVSLGAGTRAGKGAAIGIPN
                     LLVRKHSLIALDPKQELWKITSKVREKLLGNKVYLLDPFNSKTHQFNPLFYIDLKEES
                     GAKDLLKLIEILFPSYGLTGAEAHFNNLAGQYWTGLAKLLHFFINYDPSWLGEFGLKP
                     VFSIGSVVDLYSNIDRELILSKREDLEGTKGLDENALYHLRDALTKIREYHETEDEQR
                     SSIDGSFRKKMSLFYLPTVRKCTDGNDFDLRQLRREDITVYVGVNAEDMSLAYDFLNL
                     FFNFVVEVTLRENPDFDPTLKHDCLMFLDEFPSIGYMPIIKKGSGYIAGFKLKLLTIY
                     QNISQLNEIYGVEGAKTLMSAHPCRIIYAVSEEDDAKKISEKLGYITTKSTGSSKTSG
                     RSTSKSSSESEAQRALVLPQELGTLDFKEEFIILKGENPVKAEKALYFLDPYFMDRLM
                     MVSPKLTELTASLNKTKKVLGVKGLKYPSKEKMLSVGELESEVLL"
     gene            complement(11916..12950)
                     /gene="virB11"
                     /locus_tag="IRB70_003426"
     CDS             complement(11916..12950)
                     /gene="virB11"
                     /locus_tag="IRB70_003426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type DNA transfer ATPase VirB11"
                     /protein_id="HBC0633294.1"
                     /translation="MKDAENRHIVYEIIDEYFHHWLNEVDGLTEIAVNRPDELFVKVS
                     GKWQQHELKMDFKDCMSFAGAISDYHDGGSVTPEYPLRSVTLPGGERVQIVIPPATER
                     ETVSITIRKPSSVFIDHDTFVKQGFYSRLNQGGKFRDKEDELSSMFKDNCFEQFVPEC
                     LVKGKTMVFCAGTGAGKTTFANACLQYIPHHLRCISIEDTDEAKFRFHKNHVKLYYPS
                     EGESSTVSSASLLRSGFRMNPDRILMTEVRGAEAWDFLKGSSSGHAGNLTTVHESTPE
                     DAVLGLVQRCYMNPECQNLPYNIILRRVLSNVDVIMSIKYIDEEDNRFASGIYYRDIH
                     FQEYFEKLKE"
     gene            complement(12947..13144)
                     /locus_tag="IRB70_003427"
     CDS             complement(12947..13144)
                     /locus_tag="IRB70_003427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000629109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBC0633295.1"
                     /translation="MITLDIKEFSMLLGIRESEIYHHIRKGIPINGVPFPKPLKQIKT
                     HRFNYEEVMRFIEDLKGKGEL"
     gene            complement(13146..14360)
                     /locus_tag="IRB70_003428"
     CDS             complement(13146..14360)
                     /locus_tag="IRB70_003428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001295060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbI/VirB10 family protein"
                     /protein_id="HBC0633296.1"
                     /translation="MSEQENKIPTAVEIEQALRERHQKEIEQNDKTDKGDEDDGKSVK
                     RLGIEKLKKSRKGLVIIVAAFLLLAAGVSVYYIPSIIRAMSSGDDKPASNAVSTGSVK
                     RATGLSDDVDPFNTREEPAKTEERKESSGKAETPPEKVQQNFSRALDVAYGGSSSASS
                     NSGGSSSTASNTRNEGDGSDKQAEVQPVNAGQPAQLSKITRVPYDPNLFIPENTAIKC
                     SLDRRFISDLAGKLVCTINEDVYSANRNVKLIEKGTAAYLMYKTGTFNHGQGAVFIAA
                     TKLRTRKEPFIDIPLIDTQAAGALGEAGASGWIDTHFADRFMGAMMVGMIPDVAQAAS
                     GAAKSNKDNQTDYTANSRQAFADIAREAFANSVNIPPTLYKNQGEIITLIVGQDLDFS
                     SIYKLKMVGTRR"
     gene            complement(14357..15286)
                     /locus_tag="IRB70_003429"
     CDS             complement(14357..15286)
                     /locus_tag="IRB70_003429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000783379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbG/VirB9 family P-type conjugative transfer
                     protein"
                     /protein_id="HBC0633297.1"
                     /translation="MKMNKGALIVALLLVSHVCHAAVTPAASRFDPRNQIVSYNPQNT
                     TVINSAVGYTTTLVFDEDETVISARTGFPQGWEVNKEDNLVYLEVKPVKQTVQKNSTD
                     DNGNQSSEVVSVALDPENDLERWRTNLFVRTTKRNYSMELNARTFRQPDKIAFVVNYQ
                     YPQERRKEQAEIEKKRIEALNKRQEEQAINRSLENAKSPKNWDYWKRVADGSQSISPD
                     YAYDDGRYTWFGFSPLKKIPSVFVMSGEQETLTNPVVKNSGSFTVVGVPVDQRFVLRM
                     GNQVVGVENRGFGKVRLPAGDTVSPNVEKEVIQ"
     gene            complement(15292..16020)
                     /locus_tag="IRB70_003430"
     CDS             complement(15292..16020)
                     /locus_tag="IRB70_003430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004199085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HBC0633298.1"
                     /translation="MGFKLSGLKLPGFNKKKEVTDSSTTFEEKNVLMQEKMNRIYKFG
                     GIAGIAVGVLSLLALNGALPLKSTVVEAYLINGVTGVAERLTSVKKENLSENEALAKY
                     FITQYVKRREGYNYFSLQHDYDYVLLYSAENVATDYNALINGNQSPKVIYNKAEKTAS
                     VQDNPSVIISPSSRRDDKDMGAYIRFKLTIRNVATGQDDYEYWNVRLTYRIEPQVEMA
                     SGDRNNNPLKFVVTSYVRDKEVKG"
     gene            complement(16215..17270)
                     /locus_tag="IRB70_003431"
     CDS             complement(16215..17270)
                     /locus_tag="IRB70_003431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion system protein"
                     /protein_id="HBC0633299.1"
                     /translation="MATSRYFQAAHDVIVKTLDQSLTGQLDNFSSIASQLGKYGISIY
                     ILWYAYTTIVGKQKTAVQDFLWNLCRFWLILVFVKNMGGWLDSATQAIDGLKETFAGG
                     DPWKWVDELWEKVQQVAAYLMSKDTSKYVKTDGAIASLLTYAGGIIALLLTSIVYLAA
                     EVTIKILTITAPLFIICLSFGFLRQMFNSWLQLIFSSCFIFLFCGLAIKAGMTFLNGI
                     LTISIANADELNLISTGAQAGVAGAFMAWIIWQAKTYASQLAGVGVEGAMQGAAAMGI
                     GAGVFGASRMGRNLLGMGKNAGIGAWKGVRRQDGGFNQSPGVSGKLGNLTGQGVNIGA
                     KRLRQAAIDAAKKKYGG"
     gene            complement(17282..17539)
                     /locus_tag="IRB70_003432"
     CDS             complement(17282..17539)
                     /locus_tag="IRB70_003432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000759841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EexN family lipoprotein"
                     /protein_id="HBC0633300.1"
                     /translation="MKKYGLVAALGLTFFLTGCEEVKSVDWWQSHVDDATKKVAECKK
                     SGSDSENCKNAKEGLFRYKQLHPKHVDYKDAFKNVLGKDGS"
     gene            complement(17549..18319)
                     /locus_tag="IRB70_003433"
     CDS             complement(17549..18319)
                     /locus_tag="IRB70_003433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pilus assembly protein"
                     /protein_id="HBC0633301.1"
                     /translation="MKKHIVAALIASVTVISGAQAGVPVAIDANPEWAVEAQRWTERL
                     KQWQDTVNHYQKQINAYKQELLTKTGIRDVQGLVQSAQSVSKELENIYDQGNSFIDDY
                     IKNPEATLSEQARSLLADYKVTNTCKGLGYTGDLVRGCEASFLSQLAGIEYGNKLESK
                     LREDNQEMADLIDQVKNAQDTKATQDATNAVSLASLKFNKLKFQYEMYRDKQRDLAEY
                     KEKMLQAAFQEKQLGAVNKETPVVDYKAAFEQQSYEMN"
     gene            complement(18329..21082)
                     /locus_tag="IRB70_003434"
     CDS             complement(18329..21082)
                     /locus_tag="IRB70_003434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VirB3 family type IV secretion system protein"
                     /protein_id="HBC0633302.1"
                     /translation="MSTVFKGLTRPALIRGLGVPLYPFLGMCVICVLLGVWIHEAMYA
                     LILPGWYAIKRVTKIDERFFDLLYLRMQIKGNPLANKRFNAVHYAGSSYDAVDISKVD
                     NFMKLKDQSSLEELIPYSSHITDNLIVTRNHDLLATWQIDGAYFECVDEADLALLTDQ
                     LNTLIRSFDGKPVTFYTHRIRVRKEVRPVFDSKIPFVNRVMNDYYESLSAAEYFENKL
                     YLTVCYKPFSAEDKVTHFLSRKKGNKNIFEEPINDMNEICGRLSTYLSRFHSRRLGLY
                     EENNIVYSEQLTLFQKLLSGRWQKVRVTNSPFYTYLGGKDLFFGNDAGQITASDHARY
                     FRCIEIKDYFQETDAGIFDALMYLPVEYVQTSSLTPIDKQSAIKALDDQIDKLEMTDD
                     AAKSLLADLKVGLDMVSSGYISFGKSHQTLIVYADSPERLVKDTNIVTTTLEDLGLIV
                     TYSTLSLGAAYFAQLPGNYTLRPRLSSISSLNFAEMESFHNFFTGKEKGNTWGNNLIT
                     LGGSGNDIYNLNYHMTTEHQNYFGKNPTLGHTEILGTSNVGKTVVMMTKAFAAQQFGT
                     PESFPPERKLKKLTTVFFDKDRAAEPGIRSMGGAYFRVKEGEPTGWNPAALPPTKRNI
                     SFMKDLVRLLCTLNSEPLDDYQNRLISDAVERLMQRSNRSYPISKLRPLILEPDDTET
                     RRHGLKARLNAWVQGGEFGWVFDNPDDTFDVDNLDVFGIDGTEFLDNKVLSSAASFYL
                     IYRVTMLADGRRLLIYMDEFWQWINNEAFRDFVYNKLKTARKLDMVLVVATQSPDELI
                     KSPIAAAVREQCATHIYLANPKAKRSEYVDELEVRELYFDKIKAIDPLSRQFLVVKNP
                     QRKGESDDFAAFARLDLGKAAYYLPVLSASKPQLELFDEIWKEGMKPEEWLDTYLERA
                     NLI"
     gene            complement(21107..21397)
                     /locus_tag="IRB70_003435"
     CDS             complement(21107..21397)
                     /locus_tag="IRB70_003435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000916156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrbC/VirB2 family protein"
                     /protein_id="HBC0633303.1"
                     /translation="MLKLNKRYLTLSVFMAALMLCVAEPAFADDVSTKTTGFLQKIID
                     FLTDIRKPAITIIALVIGYIAIFSRQHAAWITPLIIGIIIFIVAPYLPDWLA"
     gene            complement(21381..22025)
                     /locus_tag="IRB70_003436"
     CDS             complement(21381..22025)
                     /locus_tag="IRB70_003436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000953524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic transglycosylase domain-containing
                     protein"
                     /protein_id="HBC0633304.1"
                     /translation="MLSTTAFAALALQCAASVHPDTAHEVARVESGFNPYAIAEIIPK
                     VERKPGDKGVVSYFPKTKEAALQIVNQIESRNHRYSVGLMQITSTNFANFNTTAEKMF
                     DPCENLKVSEQILVDCYKRGGDILRGLSCYYSGNPETGTKPESDFNNTSYIQRIGFNP
                     PDNKKNWVVPSVKDAIRKENVTQSIKPKEVTVYPQYAMRGTVLDEKETNDVKTQ"
     gene            complement(22071..22307)
                     /locus_tag="IRB70_003437"
     CDS             complement(22071..22307)
                     /locus_tag="IRB70_003437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633305.1"
                     /translation="MTATRKKTATRRKPQRNTLYLPSASREELDKIALEIGYRRGRRI
                     SSSGVVQYLIKKYSSQAIEELINEDDEDDDDFDD"
     gene            complement(22258..22767)
                     /locus_tag="IRB70_003438"
     CDS             complement(22258..22767)
                     /locus_tag="IRB70_003438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000455437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor NusG"
                     /protein_id="HBC0633306.1"
                     /translation="MEWYVLQFTTTRFAAVFAHLERLNFSYFCPMETERYRRPDKIIS
                     YRERRLPLFPGYLFIQADFEEVHSTTITAIPYVQRFISFGGEPLPVPEDVMAELLYRQ
                     SHTTAQANLLRKSIPHDFAEILLMDNPQQRSMAFIHYITERSLTHKMKRKKNDCYPKK
                     NRNETQAPT"
BASE COUNT         5965 a         5608 c         4816 g         6477 t
ORIGIN      
        1 gctggtcact aacgccgtcg tgttatggaa cactatttat atgcaggcag ccctggatca
       61 tctccgggcg cagggtgaaa cactgaatga tgaagatatc gcacgcctct ccccgctttg
      121 ccacggacat atcaatatgc tcggccatta ttccttcacg ctggcagaac tggtgaccaa
      181 aggacatctg agaccattaa aagaggcgtc agaggcagaa aacgttgctt aacgtgagtt
      241 ttcgttccac tgagcgtcag acccctgtta ccgatgcaag aacaggggag tttcatgaaa
      301 tgcctgttta ggagtgatta aaggtaactt gtgcgcagaa ggtcaggtgt gtggtggtta
      361 gtacagacta gtgaatgttg taactaaact atatttttat taaaggccgg aggtggtgtt
      421 cctccggcct taattacgtt tccgtgttca ttagtcgatg aactggcgga tcagttccag
      481 aatggcaatc agcgcgtttg caagcgccgc taccgccctc agaacgatga ttaacaggtt
      541 aatcatccgt tttctccata aatggagtaa agacaccgtg gcttgctctt acactgcctg
      601 tcaccacggc ttctcttcgt cttgtcagtt gtagagagtc tcactcctgc cagagcacag
      661 ataaccagca ccacctgtat tacctgtcag gactttgaac ctgttcatgc cgcatttagc
      721 ggaatgcagg gagagactca ccacagagct aaccctctga ttatacgttt atctaacgtt
      781 caggcaaacc gttaacgcac agtcactgcc cgtcatattg cataatcagg cttcacggat
      841 tatcatacta ttgtcagttg tagagagttt cccttccggg ctgagttacc agctcgcacc
      901 ggaaccgtaa aaaagccgac ctcaccagtc ggttttttta cgtctgcggt ttcccgcttc
      961 gtttaaatct attttaaatg aataaattgt tctgcggcaa acccaacaac ataaggacgt
     1021 tagggttgat ggttgccgaa atcgcggtgc gttacgtgaa ttctgaggtt ttgcgagggg
     1081 gattgggcgc gagaatttac gagagagcgc cggaacaatg ccgggatcac aaaccatcac
     1141 ccgtgaaaga aatcttccgg cattgcccgg tcaggtagta tgacattcat tgtcaacggc
     1201 catcaattta taagctgctt tgcacttcat aaaagatcac caccagggct gctaaaacag
     1261 taccgatagc cagcacgtta aaaagtacgt ccttcatctt tacgaacgac atactgattt
     1321 gcgtcctttc ccttttgtca gccttctcta tcatccagcg ttggtatgaa tcactgttac
     1381 tttttctgtc catgttcccc ccaattcatc aatgagcacc aggcggccac caggcttctt
     1441 gccaacaaag taacggcctc gcggcagacg ttcgccagtc ttcagccgtt cgatccagtc
     1501 ctgaaatgca gggcgcggtt tatagctgta gcggccaaaa tcagctaaag actgcgtgac
     1561 catgactgtt tggcagccat gctttctcat atcacgaaac gtattttcca gtgcagccag
     1621 tgtattcatt tgcacgttct ctctgctttt cccatgaaga tattaacgac actcaaaact
     1681 aacaccgttg gcatgatcac ggcagcatag ccgacagcaa cggcctgata tatggtcaat
     1741 gagtagtcgg gctgtttata caatacgact gaaaaaatgc tccccaaaca agcaagcaga
     1801 gttaaaaaca agtaatcgac aaatctgttt ttatagataa cccatgcaac gatgcaggga
     1861 tatgacacca ggcacaggat aatcgcattt gtggtatgca cgtttcgctc cttgttattt
     1921 aagggttgtc agccagatca aacagattgt tcaggctgga acggaattgt tttaccgatg
     1981 ataccagctc ctgactccgc gctttttcct gcgccagttc acgccgtagc tgcgccatct
     2041 cgtctctgtt acgctgaagc tcaaggatag ccgtcataaa ggttttgctg gctgatgcct
     2101 gtccggtcgc ttcctgcgcc tttttaatgg cctgatcttc gtcgtcattc gttctgattg
     2161 tgtaatgccc catgataccc ctcttttgct gtcatttttg cgctgccggc gcgaacccgg
     2221 gaagaaactt tgctggcaaa aaacactggc caacagatgt gaccgggaaa atttgctggc
     2281 aattaatttt cgatgaaagc cagctcgcaa tcgccgcatt caatattcag tccggctttg
     2341 ccccacacgg cagcgccaca cccgcgacac tgatatttaa ctttatttcg ttttggcttg
     2401 tcctcaaatg ctgcaactga caaatcattg tcattgctcc cggccatatc atctgaatgg
     2461 ctcccgttct gcggtgacac tgacggcagc agagccatag aaagcaccgc ttctatatca
     2521 atcccggcct cagcattttg atgcgccaga gcaagcgttt cgcgccattg ctctattacg
     2581 gcggtcatat ctttttgttg ttcgacctgg acagggaagc gatcaaacca gctcaaagca
     2641 aattgcccct ggaacagttc cagtgtgacg cgctggaagc ggccaccagg gatcggatag
     2701 tcattaatct tctggccgac tttcgcacca ccaggtctcc cggtggagga gggcataagt
     2761 ccgatacttt ccatttttgc cgcccactgc gcattgtggt acgtcttacg cgacgggttg
     2821 ccgtagtggt actgccacat atggcactgc tcatgaacca gcgtttgcat gacttcaata
     2881 agcgggtaca ccgggaagta ttcaggattg agggcgattt catcaatcat cctgccgctg
     2941 ccgtcagcag caacaaagcg cctgtaactg aaatagccca ttgtgttctt gccgcgctgg
     3001 aacgtaatca gacagtcagg gagttcgccg tcaaaaaggc gctggttata gaaatcaaac
     3061 gcctgttgta gctcgctgta agcgcgttcc gtggctcttg tcatgctgaa gttcgcttag
     3121 cggcgttccg atattcctgt aactctgcaa caatagcagg gaacacatca gcgcaacgct
     3181 gtgccagctt aaccgccttt gaacaaacgc ccataccatg tgctcttttg agcgcctcca
     3241 acaaatctac cagttcctcg tcagtgattt tttcagtcat ctattaagct tctccattat
     3301 ctgtatcgta cgatacagat aatataaacc acacctttga tagcggcaat cttttttgct
     3361 ggcaatttca cgcccagggc gggcatcgag cgggtaatat tgctggcaaa aatcaacggc
     3421 caaaccggct gcaggaaact ggtttgctgg caagcgtgat ttactgctgg gcttgacacc
     3481 ttgccattgt atgacgcttg ttttagtgtc aaatgaacaa ccagcgcgag aagaatatag
     3541 gaagcaaaag caatggatat caaacctaac tcagtgatcc acctggagcc aggcgaaaca
     3601 ttacccggct ataccaatct gaaacccgta cctgataagt atttcgatga gttaaaggca
     3661 ctcataaata aactcaatac tcaatccggt aatatttacc tcaagttaaa acagatgtac
     3721 gcctttttgg atcgttttaa caaagaattt gtgagcacgt ttacctcctg tcaaaagggg
     3781 tgctcttcgt gctgtaaaat ggatgttcat ttaaccgcgc ttgaggcaac acatattgca
     3841 caagcaagta aacttactgc cagagacaac ccgcttacga ccgggcatga gtcaaaatgt
     3901 ccgtttttgt ctgagaaggg aacatgctca atctacaatt accgcccgct gttatgcagg
     3961 acatatcatg tactcactcc gccggagatg tgtaatgacc tggatgcaca agtcatgcag
     4021 tatggttctc aaagcgcgaa catgggaaat cacatctaca aaacaatagc agagtggatc
     4081 tattttcaga cgtatcactg cactggtaag ttagaaacca aagatatcag agactacttc
     4141 ccttatcccc gcgaagatat ccaaagattt cttcaccata accccccgcg ccctttttgc
     4201 taaaaaaaag cctctgacgc agtgtcagag gcttgttaga ttactgttcg tcaccagcag
     4261 tgctggaagc atcttttttg atgagaaact catcaagaga acggccagct tttaacgctt
     4321 cgtcgattgg ttttggtgtc cggccacgac cagaccagta tttcgtttcg ccgttttcat
     4381 caaactgata tttaggcggc gcttttggca acgtcttttt gcgtgttttt tgcgcatctt
     4441 cggacaggcc aagcagttct tccggtgaaa aaccttctcc ggcaatcaac tggagcagtt
     4501 cctggcgctt tctttcgcgc tctgcgcgtt ctgctgcctc acgctctgct tcttcacgac
     4561 gttcttcgat cacggcgtta agcttttcct gcatttccag cagttgttca aagctggttt
     4621 ctcgcgcaaa aacacgaaca gagcgaatat tcaggagtag cttttttgtt gcgtcaaacg
     4681 tttcattttc actcatcgag ttaatcctta ttttttactg aactgaaacc caagtttacc
     4741 cgtagtttta tcctgcaaaa caattgcagc gtcaaacttt ttcccggttt tattactggt
     4801 aaagccttta atctctccgg ttttaccttt tttgattaat gtctcaacct gattttgtgt
     4861 cagttttttt cctgacactt cagaccagat tttaaactcg cacccggaac agaaaaagcc
     4921 tttaggccgg ataataattt ctttactgca tgaagggcag ggggcttcga gccgggacat
     4981 ggaaccttct gatctggatt ttgcttccat atccggtttg ccgtctttgt ccgggaatgt
     5041 tgtcttgcat tcagggtagc aggagcatcc ccagaaaaag ccattttgcc ccttacgctt
     5101 acgcaggaaa ccgttgttac aaaccgggca gggcgtggca tttgaagaaa tcgaaattcc
     5161 gttcctgtcc agctcgtcga ttaacccctg gacgtactca tcattttcct taataaactc
     5221 ctcaactgtc agctctccgg ctttgatctg agactgcttt tcagcccaca gagcggagat
     5281 atccggttta gtgatttcag gaggcagtgc agcgcaaaac tcctggcctt gttttgtggt
     5341 tttccatacc agctccgaat accccttttc tttttcgatg gagataagcc cggtatttgc
     5401 cgccagtttc tcaagaatac ccgcgcgggt ggcttccgtt ccgatactgc cacgatcact
     5461 gctgccctcg tctttcgctt ccagcgcctt tctgagagcc ggatcatcaa tgaattttgc
     5521 cgcactcgtc atggcggcca gtaacgttga ctctgtgaaa tagcgaggtg gtgtagtctt
     5581 tttcttgtcc acgtctgccg attcacacag gccgctgtca ttaaatttca gcaatgaaag
     5641 gtcaaaaccg tccgttccgg catcttcggt ttcgtcctcg tcatcactat ccttacccag
     5701 cgcttcccag cccttttgta ccagaacgct ctgtgtggcc gtaaaggtat cccccttaat
     5761 atcaaagtgg attttcgtct tgttgcggat cgcatccggg tagaacagcc cgataaagta
     5821 gacggacacc aggttataaa cgttccgctc tttttcatta agctgaatac cggctccgct
     5881 ttttgtcgtc gggatgatgg cgtggtgcgc ctcaatctta ctggcattaa aggctttgtg
     5941 tttctggcct ttatccatat ctacgatcgc agacgccagt tcgggtacgg tggccgctat
     6001 agcagtggca atatctccgg cctggtaata atgctcatct gaaagatagc gattgtcaga
     6061 acgtggatag gtcagaagct tgtgagtttc atacagcccc tgcatcacat cgagcgtatc
     6121 ttttgcagaa taaccaaatc gctttgcgca gagctgctga agcgtggaaa ggttaagcgg
     6181 aagcggaggc ttgctatttt ccggctttgt cgtcgcgata gtaacaatag catccttacc
     6241 cgtaacacgt ccggcaatat gcgcggcctg agcttcggag atcaggcgtt ttttctcgtc
     6301 tatctgatcg tcgtctgttg tctgatattt cgccttaatc tgatgcccgt tcatcgacag
     6361 actggcgaat acatcgtaat aaaagctttc tgtgtgattc tggttcgcca gcgtgcgcat
     6421 gttcaccaga ccaagaacgg cactttgtac ccggccaacg ttcagaacgc cgtcatagcc
     6481 cttctcacgg ccttttaatg tacatccccg cgtcatgtta tagccaaaac cctgatcgca
     6541 cagggaacgc gccagggcgc ttaacgtcat accgcgaaat ttatcgttag gttgtaaatt
     6601 cgacagtgat ttttgcactg gcgcaaggtt gaggtcggca acaagcagtc gctggacggg
     6661 tttcttgttt ccggcataac ccagaatctc atcaaccagc aaacatcctt catcatcggg
     6721 gtcgcctgaa tgaacgatgc tgtcggcttt atcgataaga gacaaaataa tgcgggtctg
     6781 tgcttctgat tcaggcttga ttttatattt tggcggataa accgctttaa tgggtaaatc
     6841 actataacgc cagttggaat atttgtcgtc ataatcctgt gggtcgtaaa gctccagcat
     6901 atgaccataa caccaggtaa cgacatcaga accgtgttca aaatagccgt ttttcttttc
     6961 tgtattggga tttccgccca gtccttcaaa aatagccttt gctaaagacg gtttttctgc
     7021 aataaaaagt ctcattaatc aatcctcaag gtaacttgaa tagtcaggct gcgcaccatt
     7081 ctttttaaag atttcttccc tttcctctat gtcttcttct gcctcctgca cactaaggtc
     7141 aagggttcct ttcaaaaagg cacgcgcatt cttgattaca tctactgtta attcgttttt
     7201 tgttccgcga atcatgccaa tagcaatatt tattatctcc tttatttcag caggagtcgt
     7261 tctgtccagc accgcgccaa gttctttaag gtcaatattt atatcgtctg gtaagtacat
     7321 tttggcacaa gcggcagcgg ctttagtccg aaaagcacct acagatatga ttctgtcaat
     7381 tctgccaggg cgttttctga tgcgcggatc aatccggtta ggatagttcg ttgaaaaaat
     7441 aacatatgtc ccggcaagat ttcgcggtgt atcagcccca tcaagaaaac ttaacgttcc
     7501 ggcatcagcc cgataaagtt catcaacctc ttcagctatt atgataacgg gtattttctt
     7561 ttgagctgcg gcatagcaaa catctttaaa gtaatcatca gcataaacaa atacatattt
     7621 atcctgatat tttgccccca aagcttttgc gatagtcgtt ttccctgtgc ccggaggacc
     7681 agtaaaaagc acttttcgca ttcctgactg accataacgg gtgtagaaat caatatccga
     7741 aaagaactga ttaaagtcat tctccagctc attaaacttt ggatgaacag aaaaacgtaa
     7801 agcgttttct atttcttcct tccttgcctt accgtgataa taaacgccgt cgtaacaccc
     7861 gattttccag atacctttac ggggtaaaga gcggtttaat ttagcgcgtc cagcttcgca
     7921 aagattatga agcatcgaca tacttttggt tgtgccaact gcgtactcca ttctgacttt
     7981 agagttaaga atgaagcgaa taatatgaac cacttcattt tgaccaagat gaatccggta
     8041 tgctcccgaa ccatctttaa acataagctt tttaatcctc ccggctttag ccataacagg
     8101 gctacttccc gtatgaacga cggttgaagc aacgggttcg atatcaagat tcgaataaat
     8161 tttacgattc tttctgttta taaaaatctc tgccacttta ggatagtaat cacaatcctt
     8221 tacgacagta ccaaaattat cttcaccgta atattcttta tggagccgta aagcctgctc
     8281 taccagagtt aatttaccca tatgcgcacc atgtatatta aaaaccgtga cgttgcctga
     8341 agattttctt caggcagagg aggggttgga caagcgaagc gcgtcagttt tgtttatgac
     8401 gccactccca cggaggaacg ggattactgt cagcccacag gccgcgcttc tgtgtctgag
     8461 cttcccgttg cagagccggt aatgagttat cggtgttgta cctgtcataa acccatgcag
     8521 ccccttttag cacttgctgg cggttagcct cagtgccgtt cgctgtcacc actcgtccca
     8581 ggactcgccc gtagcgatct gtttgcgtat aagagacggt aactgattgc cctgccagca
     8641 gggctttaag ttgattggtt gaccagcgac caaagggttg ttttttttcc ggtgcatcga
     8701 tatttatcaa tcggactcga atcggaactt catacacaac aattttcgcg ggtagtgttt
     8761 taacttcgat ggtatctcca tcgagaacgc gaataacttt cccctgaatc tgagcagcac
     8821 acaatgtagc tggcaacagg gcaacagcaa aggaaagaac attaaaaaaa tgtctcattg
     8881 ctttcttccc tcccatattg ctgagagtct tttaaaaatg gataaaacga cgactaaagc
     8941 cactgcgata acagccaacg aaggaagtac atagctgtat aactcaacca tgaaattaat
     9001 aaactcaatg agcgattgcg gctttaagga agcatcccac aaaacgataa caaaacgata
     9061 aagcccatag acaattgccg gaaaccagac cataaacaac aaaatttcag taaaaacaga
     9121 agcgaccgat ttgacactat cgataatttc aattccggca attctcacac ttcttgcatc
     9181 aggtacgtta ataattttca tcctcccacc cctgtaaaaa atgttcgcaa gttccagtct
     9241 caaacctgaa acttgcgtat tcacatcaga attaaatcaa acagaattaa aagtttttca
     9301 atcggccaaa gcttgaaata attttactta ctgtacctgc atcagccgca ggacattcat
     9361 ttagtttttt ctttctggca tctgccgtgt gatcgggtaa aaaaccatgt ttattctttt
     9421 tcctgattga cataaaactt ttatacatcg ggtcacattc tgccggacta cttccgtcaa
     9481 gttttccggc aaggcataac accattgcac atggatcgtt cgggtcggcc ttttcctcag
     9541 catgagcagt tccggcagcg aacgcacaaa gcagcactgc cgtggttacg gtctttttca
     9601 tatacacctc atggataacg ggcaactaac gccctgcggt tgttcaaccc cggctcaata
     9661 aaattacaag aattttatta atccggcgtt atcgtgataa ataaacactg gtagtccggc
     9721 aagaaaaaca gttcatttta taacgatact gtatgacacc gtttgcaccg ttcgccctca
     9781 accagttttt agctgtgaaa aagtctgttc cgttactggt ttcaacaatc actgaatcag
     9841 aatgtgcaac agaataaaaa acagcatcat cgtaaaggcg gttttcaggc ctgaaattat
     9901 ggataacctt aacccacgat gaattaacct tgtctgattt aataactgag tatgtcggtt
     9961 gccagtccat taattgtgta ttcaccgttt caggattctg ttcccagtca acctgtggtg
    10021 gttcaggcgg agaggaacag gcagagagaa aaaggacact gaccattaac atttttttca
    10081 tagtaaaacc tctgactcca gctcaccgac ggagagcatt ttttctttag aaggatattt
    10141 aagcccttta acacccaata cttttttagt cttattcaga gaggcggtta actcggtaag
    10201 tttggggctt accatcatca gcctgtccat aaaatacggg tcgaggaagt agagggcttt
    10261 ctcagcttta accgggtttt cacctttaag aatgataaat tcttctttaa aatccagcgt
    10321 tcccagctcc tgcgggagca caagggcgcg ctgcgcctca ctttctgaac tgcttttcga
    10381 cgttgagcgt ccgcttgtct tgcttgaacc tgtcgatttg gtggtgatat agcccagctt
    10441 ttccgaaatc tttttagcgt catcttcttc actgacagcg tagataatcc ggcagggatg
    10501 cgcactcatc agcgttttgg caccttcaac accatagatt tcattaagct gactgatatt
    10561 ctggtaaatc gtcagaagtt tgagtttaaa cccggcaata taacccgaac cttttttaat
    10621 gattggcatg taaccaatag acggaaactc atccaggaac atcagacagt catgtttcag
    10681 tgtcgggtca aagtcagggt tttctcgtaa cgtgacttcc acaacgaagt taaagaacag
    10741 gttgaggaag tcataggcca gggacatatc ttcagcatta acgccaacat aaacagtgat
    10801 atcttcccgg cgcaactggc gaaggtcgaa atcattgccg tctgtacatt tgcgaacagt
    10861 cggaagataa aacagactca ttttcttacg aaacgaacca tcaatactcg aacgttgttc
    10921 gtcttcggtt tcgtgatact ccctgatttt ggtcagggca tcgcgcagat gatacagcgc
    10981 gttttcatca agtccttttg ttccctccag gtcttctcgc ttactgagta tcagctcccg
    11041 gtcgatgttg ctgtacaaat cgactacaga accaattgag aaaacaggtt taagcccgaa
    11101 ctcaccaagc caggaggggt cgtagttaat aaagaaatga agcaattttg ccagccccgt
    11161 ccagtactgc cccgcgaggt tattaaagtg tgcttccgct ccggtcagac cgtaagacgg
    11221 gaacaggatc tcaatcagct tcagcaggtc tttagccccg ctctcttctt ttaaatcaat
    11281 atagaaaagc gggttaaact gatgcgtttt actgttgaaa gggtcaagaa gatagacctt
    11341 attacccagc agtttttcac gtaccttact ggtgattttc cacagttcct gttttggatc
    11401 taatgcaatc agggaatgtt tcctgaccag caggtttgga atacctattg cagccccttt
    11461 acctgcgcgg gttcctgcgc caagtgatac aaaatctggt gcggtatacc acaggtattt
    11521 acctttatat gcacctacaa gaatatcagt atcgttttct ttctcccatt tcagaagttt
    11581 cgattttctt aaatcattat cactggcaaa cttcgcgtca ccataaagag caacatccgt
    11641 tttattcagt tgccagataa taaaaacagg cacaatgaga gacgaaacca tacctgataa
    11701 aagagagggg attgcggtta acctgatatc tgtccgtata ttactctctg ttattatccg
    11761 ccacagcagc atggaatcaa aattcttcca tatataaagc ggcgtttttc cgttcaggaa
    11821 gtaaacagca actgagccag tataatacgt cacaagacac ataaccagac cgataaaagc
    11881 ccactggcct ttatcgggta gtttcagaga cataatcact ccttcagctt ttcaaagtat
    11941 tcctgaaaat gaatatcacg atagtaaata cccgatgcaa atcggttatc ttcctcatcg
    12001 atgtacttaa tactcataat cacatcgacg ttgcttaaca ccctccgcaa tataatgtta
    12061 taaggcaaat tctgacattc agggttcata tagcaccgtt gaaccagtcc aagcacagca
    12121 tcttcagggg tgctctcatg gacggttgta aggttccctg catggccgga acttgagcct
    12181 ttgagaaaat cccaggcttc cgcgccgcga acctcagtca tgaggattct gtccgggttc
    12241 atacgaaaac cagaacgtaa aagagaagcg gaactgacag tgctactttc cccttctgac
    12301 gggtaataca atttcacatg atttttgtgg aacctgaact ttgcttcatc tgtatcttca
    12361 attgaaatac atcgtaaatg atggggtatg tactgaagac aggcatttgc aaaggtggtt
    12421 ttacccgccc ccgttccggc acaaaatacc atcgttttac ccttaaccag gcattcaggg
    12481 acaaattgtt caaaacaatt atctttaaac attgaagata attcatcttc tttatccctg
    12541 aatttccccc cttgatttag ccttgagtaa aacccttgtt taacaaaggt atcatggtcg
    12601 ataaacacac tggacggctt acggattgta atagacaccg tttcccgttc cgttgccggg
    12661 ggaataacta tttgtacacg ctcccctccg gggagcgtaa cagaacgtaa gggatattct
    12721 ggcgtaaccg acccaccatc atgataatca gaaattgccc ctgcaaatga catacaatct
    12781 ttaaaatcca tttttaattc atgctgctgc catttcccac tcactttaac aaacagttca
    12841 tcaggccgat ttaccgcgat ttcagttaaa ccatcgactt cattaagcca gtggtggaag
    12901 tattcatcta ttatttcata aacaatatgt ctgttctctg catccttcat aattcacctt
    12961 ttcctttaag atcttcaata aaacgcatga cttcttcgta attaaatcga tgcgttttga
    13021 tttgtttcag tggtttgggg aaaggaacgc catttattgg tatgccctta cgaatatgat
    13081 ggtatatttc gctttccctt attcctaaca gcattgaaaa ctctttgata tccagcgtta
    13141 tcaaattacc tccgggtacc caccattttt aatttgtaga tgctggagaa atccaaatcc
    13201 tgaccaacga tcagagtaat gatttccccc tggtttttat aaagcgttgg agggatattt
    13261 acgctgtttg caaacgcttc gcgtgctata tcagcaaaag cctggcgact gttagctgta
    13321 tagtcggtct gattgtcttt attactttta gccgctccac ttgcggcctg tgccacatcg
    13381 gggatcatgc caaccatcat cgcgcccata aagcgatctg caaaatgtgt gtcaatccag
    13441 cctgaagccc cggcctcacc cagcgctccc gccgcctgtg tatcaatcag cggaatatca
    13501 atgaaaggtt ccttacgtgt tctaagcttc gtagcagcga taaacacggc tccctgacca
    13561 tgattgaacg tgcccgtttt atacatcaga tatgcggctg ttcccttttc aattagcttt
    13621 acattcctgt ttgcactgta tacgtcctca ttaatcgtac agaccagctt gccagccaga
    13681 tcagaaataa atcgtctgtc cagcgagcac ttaatcgcgg tattttcagg aatgaaaagg
    13741 ttagggtcat aaggaacgcg cgtaatttta gaaagctgcg cgggttgccc tgcattaaca
    13801 ggctgaacct ctgcctgttt gtcactgccg tccccctcgt tcctggtatt gctggccgtt
    13861 gatgagctac caccggaatt tgaggaagca gagctgctcc ccccataggc cacatccagc
    13921 gcacgactga agttttgttg tactttttcc ggtggcgttt ccgctttgcc gctgctttcc
    13981 ttccgttctt ccgtcttagc cggttcttcc ctggtgttga atggatcaac atcatcgctg
    14041 agtcctgtcg cgcgttttac tgaaccagta gataccgcat tactggcagg cttatcatca
    14101 ccgctggaca ttgcacgaat aatcgacggg atatagtaga cagacacccc ggcggccagc
    14161 agaaggaaag cggccacaat aatcaccagc cccttacgcg attttttaag cttctcgata
    14221 cccaggcgtt ttactgattt accgtcatct tcatctccct tatccgtttt atcgttttgc
    14281 tcaatttctt tctgatgccg ttcccgtagt gcctgttcaa tttctacagc ggtcgggatt
    14341 ttattttcct gttcgctcac tggatcacct ctttctcaac gttcggggaa acggtatctc
    14401 ctgccggaag acggactttg ccaaagcccc ggttttcaac cccaacaacc tgatttccca
    14461 tacgcaaaac aaagcgctgg tctacaggaa caccaacaac ggtgaaacta ccgctgtttt
    14521 tgactaccgg gttagtcagc gtttcctgtt cgccgctcat aacaaagacg ctggggattt
    14581 tcttcagggg gctgaagcca aaccaggtat agcggccatc gtcatacgca taatccgggc
    14641 tgattgactg gctgccgtca gctacccgct tccagtaatc ccagttcttg ggcgacttcg
    14701 cattttcaag agaacggttg attgcctgct cctcctgccg cttgttaaga gcctcaatcc
    14761 gtttcttctc gatttcggct tgctccttcc ggcgttcctg cgggtactgg taattaacaa
    14821 caaacgcgat cttatccggc tgccggaacg ttcgggcgtt cagctccatg ctgtaattac
    14881 gttttgttgt gcgaacaaac aggtttgttc gccagcgttc caggtcgttt tcaggatcaa
    14941 gggctacact gaccacctct gaagactggt tgccattgtc atcggtactg ttcttctgta
    15001 cggtctgttt gacgggcttc acttcgagat acaccaggtt atcttctttg ttcacttccc
    15061 agccctgggg aaagccggtt ctggcactga tgaccgtttc atcctcgtca aataccagtg
    15121 tggttgtata gccaaccgca ctgtttatga ctgtcgtgtt ttgcgggtta taactgacaa
    15181 tctgattacg gggatcaaaa cggctggctg ctggcgtaac ggctgcatgg cagacgtgcg
    15241 acaccaacag aagcgccaca attagcgctc ctttattcat tttcatagtt ttcacccttt
    15301 cacttcttta tcgcgtacat agctcgttac aacgaattta agcgggttat tgtttcggtc
    15361 acccgatgcc atttcgacct gtggttcaat acggtaggtc aaccggacgt tccagtattc
    15421 ataatcatcc tggcctgtcg cgacatttcg aatggttaat ttaaaccgga tatatgctcc
    15481 catatcctta tcatcgcgcc gggatgacgg actgataatc acggacggat tatcctgaac
    15541 agatgcggtt ttttccgctt tattataaat aacctttggt gactggttgc cgttgattaa
    15601 agcgttgtaa tccgtcgcca cattctcagc gctgtataac agaacataat cataatcatg
    15661 ctggagactg aaatagttat acccttcacg acgcttcaca tactgagtaa tgaagtattt
    15721 cgccagcgct tcattttcag agaggttttc ttttttaaca gaagtcagtc tttcagcaac
    15781 gccagtgaca ccattaataa gataagcttc gacaaccgta ctctttaacg gtagcgctcc
    15841 attcagtgcc agcagagaca acacacctac ggcaattcct gcaataccac cgaatttata
    15901 aatgcggttc attttctcct gcatcaatac atttttctct tcaaaagtag ttgaagagtc
    15961 tgttacttct tttttcttgt taaaaccggg aagttttaat cctgagagtt taaaccccat
    16021 tgcgcattac ctctgctgaa ttaacaggtt cgctttttcc ggataccgga ggttgtttat
    16081 gtgacgcctg gcatccgaca aggcaaagcg tcacgatagc cgtgataagt agtttcataa
    16141 tgtgagaacc taaatagagg agtgaatatt tactgcggaa tactcagagt tgacagattt
    16201 aaataataaa tcggttaacc tccatatttc tttttcgccg catctatcgc agcctggcga
    16261 agcctcttag cgccaatatt aacgccctgc ccggtcagat tccccaactt accggataca
    16321 ccaggagact ggttgaaccc tccatcctga cggcgaacgc ctttccatgc gccaatccct
    16381 gcatttttac ccataccaag cagattacgc cccatacggg aagcgccgaa cacgccagca
    16441 ccaatcccca ttgcggctgc cccttgcatc gcgccttcaa cacctacccc tgcgagctgg
    16501 gaagcatagg ttttggcttg ccagataatc caggccataa atgcacctgc aaccccggcc
    16561 tgagcacctg ttgatatcag atttaattca tctgcgttag ctatcgagat tgtcagaatg
    16621 ccattaagga acgtcattcc cgctttaatt gccagtccac aaaacaagaa tatgaagcat
    16681 gagctaaata ttaactgaag ccagctatta aacatctgcc ttaaaaaacc aaatgaaaga
    16741 caaataataa acaacggcgc ggtaatagta agtatcttaa tagtaacttc ggcggcgaga
    16801 taaactattg aagttagcaa taatgcaatt atccctccag catatgttaa taaagatgcg
    16861 attgccccat ctgttttcac atacttcgaa gtatctttgg acataagata tgcagctacc
    16921 tgctgaactt tctcccaaag ctcgtcaacc catttccaag gatcacctcc tgcaaatgtt
    16981 tccttcagcc catcaatggc ctgagttgca ctatctaacc acccccccat atttttgaca
    17041 aaaacaagaa ttaaccagaa tcgacataga ttccataaaa aatcctgcac tgcggttttt
    17101 tgcttcccaa ctattgtggt ataagcatac cacaatatat aaatggaaat accatactta
    17161 cccaactgag acgctattga agaaaagtta tctaactgac cagtcaaaga ctggtcaaga
    17221 gttttaacaa taacgtcatg agcggcctgg aaatacctag aagttgccat agtggctcct
    17281 tttaacttcc atctttaccc aatacatttt tgaatgcatc tttatagtca acatgcttag
    17341 gatgtaattg cttataccta aacaaacctt ccttagcgtt tttacaattt tcgctatcac
    17401 tcccagactt tttgcattca gctacttttt tcgttgcatc gtctacgtga gactgccacc
    17461 agtctacaga tttaacctct tcacacccgg taagaaagaa tgtaagcccc aacgccgcaa
    17521 ctaatccata ttttttcaaa atgccccctc agttcatttc ataactctgc tgctcaaatg
    17581 ctgccttata atcaacaact ggagtttctt tattaacagc ccctaattgt ttctcctgga
    17641 aagcagcctg taacattttc tccttgtatt ctgcaagatc gcgctgctta tcgcgataca
    17701 tttcatactg aaatttgagc ttgttaaatt tcaggcttgc cagagataca gcgtttgtcg
    17761 cgtcctgcgt ggctttcgtg tcctgggcgt tcttcacctg gtcgataagg tcggccattt
    17821 cctgattatc ttcacgcagt ttactttcca gcttattgcc gtactcgatc cccgccagtt
    17881 gggacaggaa cgaggcttca cagccccgca ccaggtcgcc cgtatatccc agccccttac
    17941 aggtgtttgt caccttataa tcggccagta gtgatctggc ttgctcagac agggtggctt
    18001 ccgggttctt aatgtaatca tcaatgaagg agttcccctg gtcgtaaata ttctccagct
    18061 ccttactgac agattgcgca gactgcacca gtccctgaac atcacgaatg cccgttttgg
    18121 tcagcagctc ctgcttatag gcattaatct gtttctggta gtggttcacg gtgtcctgcc
    18181 actgtttgag gcgttctgtc cagcgctgcg cttcgacagc ccattcaggg tttgcatcaa
    18241 tggcaacggg aacaccagcc tgagcaccag aaataaccgt aacagaggcg ataagtgccg
    18301 caacgatatg ctttttcata gggattcctt aaatcaggtt tgcacgttcc agataggtat
    18361 caagccactc ttccggcttc ataccctctt tccagatttc atcgaacagt tcaagctggg
    18421 gtttcgatgc gctgagaacc ggtaggtaat acgccgcttt tcccaaatcc agtcttgcga
    18481 aagccgcaaa atcatcactt tcccccttcc tctgtgggtt tttgacgacc aggaactgac
    18541 gagataacgg gtcaatggct ttaattttgt caaaataaag ttctctcact tccaactcgt
    18601 ctacgtactc actacgtttc gctttggggt tcgccagata aatatgtgtt gcgcactgct
    18661 cacgaacggc agccgcgata ggtgatttaa ttagttcatc cggcgattgt gtcgctacga
    18721 caagcaccat atccagctta cgcgcggttt tgagtttgtt ataaacaaaa tctctgaacg
    18781 cttcgttgtt aatccattgc cagaactcat ccatgtagat aaggagtcgg cggccatcag
    18841 ccagcatggt gacacggtag atgagataga atgaagcggc gctggaaagt actttgttat
    18901 ccagaaactc cgttccgtct ataccgaaaa cgtccaggtt gtccacatca aacgtatcgt
    18961 ccgggttatc aaacacccag ccaaattccc ctccctgcac ccaggcattc aggcgtgctt
    19021 taagcccatg ccgccgggtt tcagtatcat caggctccag aatgagtggt cgcaacttac
    19081 tgatcggata agagcggttt gacctctgca tcaggcgctc aacggcatca gaaatcaggc
    19141 ggttctggta atcatcaagc ggctcactgt taagcgtaca aagtagcctc accaggtctt
    19201 tcataaagga aatatttcgt ttggttggtg gcaaagccgc agggttccag ccagtcggct
    19261 ctccttcttt cacccgaaag taagcacctc ccattgaacg tataccgggt tccgctgccc
    19321 gatctttgtc gaaaaatact gtagttaact tctttaattt cctctcaggt ggaaaagact
    19381 ccggcgttcc gaactgctgg gcggcgaaag ccttagtcat catcactacc gttttaccca
    19441 cgtttgacgt accaagaatt tcggtatgcc ccagcgtggg gtttttaccg aagtaatttt
    19501 gatgctcggt agtcatgtga tagttcaggt tataaatatc atttcctgag ccgcccaggg
    19561 tgataaggtt gttaccccag gtatttcctt tctccttgcc cgtaaagaaa ttatggaagc
    19621 tttccatttc ggcaaagttc agactgctga tagaactcag gcgtggccgt aacgtgtagt
    19681 taccaggtaa ctgagcaaaa tacgctgcgc caagactcaa ggttgaatag gttacgatca
    19741 gccctaaatc ctccagggtc gtcgttacaa tattggtgtc cttcaccaga cgctccggcg
    19801 aatctgcgta aacaatcagt gtctggtgac ttttcccgaa agaaatatag ccgctggaga
    19861 ccatatcgag accaactttc aaatcagcga gcaaggattt agcggcatca tcggtcattt
    19921 cgagtttgtc gatctgatca tccagcgcct tgattgcaga ctgcttgtct atcggagtta
    19981 aagaggaagt ctgtacatac tcaaccggga gatacatcag tgcatcaaaa attccggcat
    20041 ccgtttcctg aaagtagtcc ttgatctcga tgcaacgaaa gtaccgggca tggtcagagg
    20101 cagtgatttg tccagcatcg ttaccaaaga acaggtcttt accacccagg tatgtataaa
    20161 acggactatt ggtgactctg actttctgcc agcgcccgga tagcagtttc tggaacagcg
    20221 taagctgttc tgaataaact atattatttt cttcatataa cccaagacga cgggaatgaa
    20281 accgggagag ataggtgctc aatctgccac atatttcatt catatcatta atgggttctt
    20341 cgaagatatt tttattaccc tttttccttg aaagaaaatg cgtcacttta tcttcagcgc
    20401 tgaacggttt atagcatacg gttaagtata atttgttttc aaaatactca gccgccgaaa
    20461 gcgattcgta ataatcgttc atcactctgt tgacgaatgg gatcttgctg tcaaatacag
    20521 gtcgcacttc ttttctaacc cgaatacgat gcgtataaaa ggtaacgggt ttcccatcaa
    20581 aactacgtat cagcgtattg agctggtcag taagcaaggc tagatccgct tcatctacac
    20641 attcaaaata agctccgtca atctgccagg tcgccagtag atcatggttt ctggtaacaa
    20701 tgaggttatc agtgatgtgt gatgaatacg ggattaactc ttcaagagaa gactggtctt
    20761 taagcttcat aaaattgtcc actttcgata tatcgactgc gtcgtacgaa ctccccgcat
    20821 aatggacggc attgaagcgc ttgtttgcca gaggattacc tttgatttgc attcgcagat
    20881 aaagcaggtc aaaaaagcgt tcatctatct tcgtaactcg cttgatggca taccagccag
    20941 ggaggatgag ggcatacata gcctcatgaa tccagacacc aagcaaaacg cagataacgc
    21001 acattccaag aaaggggtag agcggaacgc ccagccccct aatcaaagcg gggcgtgtca
    21061 gccctttaaa aacggtactc atttttacgc ccccttttat tacatattac gctaaccagt
    21121 caggcagata tggcgcaaca ataaagatga taatcccgat aattaaaggc gtaatccacg
    21181 ctgcatgctg gcgtgagaag atagcgatat aaccaattac cagcgcaatg atggtgattg
    21241 ctggcttacg gatatccgtc agaaaatcga taatcttctg caagaagcca gttgttttag
    21301 tggatacatc atcagcaaag gcgggttctg ctacacaaag catcaatgca gccataaata
    21361 cagaaagagt taaataacgt ttattgagtt ttaacatcgt ttgtttcctt ttcatctaaa
    21421 acagtgccac gcatggcata ttggggatat acggtaactt ctttaggttt gatactctgt
    21481 gttacattct cctttctgat tgcatcttta actgaaggaa ccacccagtt ttttttgtta
    21541 tcaggcggat taaaccctat gcgctgtata taactggtgt tattaaaatc tgattcaggt
    21601 ttagttcctg tttctggatt gccggaataa tagcaactca ggccacgtaa aatatcgcca
    21661 ccacgtttat aacaatccac caaaatttgc tctgaaacct tgagattttc gcaggggtca
    21721 aacattttct cagcggttgt attgaagttt gcaaaattcg tactcgttat ttgcataaga
    21781 ccgactgagt aacgatgatt tcgtgattca atttgattta cgatctggag tgcagcctcc
    21841 ttagttttgg gaaagtagga cactacgcct ttgtcaccgg gcttacgttc aaccttcggt
    21901 attatctcgg caatagcata tgggttaaaa ccagattcaa cccttgcaac ttcatgcgca
    21961 gtatcgggat gaacgctggc cgcgcattgc aaagcaagcg ccgcaaaagc agtagtagat
    22021 aacatgattt tctcccggcc agaacagcgc ggaaagttta gactgaatgg ttagtcatcg
    22081 aagtcgtcat cgtcttcatc gtcttcgttt atcagctcct caatagcctg gctggaatat
    22141 ttttttatga ggtactggac aacaccagag cttgaaatac gtcgccccct gcgatagcca
    22201 atctccagag caattttatc cagttcctca cgagaagctg agggcaggta gagtgtatta
    22261 cgttggggct tgcgtctcgt tgcggttttt tttcgggtag cagtcatttt tcttccgttt
    22321 cattttgtgg gttaagcttc tctctgtgat gtagtggatg aaagccatac ttctttgctg
    22381 cggattatcc atgagtagaa tttcagcaaa atcgtgtgga attgatttcc ttaaaagatt
    22441 tgcctgagct gttgtatgtg attgtctgta caaaagctcc gccatcacat cttctggtac
    22501 aggtaaaggc tcaccgccaa atgagataaa gcgttgtacg taagggatag cagttattgt
    22561 agtggaatga acctcttcaa aatctgcctg gataaaaaga taaccgggaa aaagcggcaa
    22621 acgtctttct cgatatgaaa ttatcttatc cgggcgacga tacctttcag tctccatagg
    22681 acagaagtaa gagaagttca ggcgttcgag atgagcaaaa actgctgcaa atctcgtagt
    22741 ggtgaattgc aaaacatacc attccatagt ttttcctttc aggcgctctc tcgactcgga
    22801 tgaccccgaa tcagagaaaa aaaacaaaag gacaaattta catctcataa aaactttatc
    22861 agctac
//
LOCUS       DADXDL010000075        22820 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.075, whole genome shotgun sequence.
ACCESSION   DADXDL010000075 DADXDL010000000
VERSION     DADXDL010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22820)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22820)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22820
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.075"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..209)
                     /gene="tuf"
                     /locus_tag="IRB70_003439"
     CDS             complement(<1..209)
                     /gene="tuf"
                     /locus_tag="IRB70_003439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBC0633307.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVE"
     gene            complement(280..2394)
                     /gene="fusA"
                     /locus_tag="IRB70_003440"
     CDS             complement(280..2394)
                     /gene="fusA"
                     /locus_tag="IRB70_003440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020455498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBC0633308.1"
                     /translation="MARTTPIARYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVH
                     DGAATMDWMEQEQERGITITSAATTAFWSGMAKQYEPHRINIIDTPGHVDFTIEVERS
                     MRVLDGAVMVYCAVGGVQPQSETVWRQANKYKVPRIAFVNKMDRMGANFLKVVNQIKT
                     RLGANPVPLQLAIGAEEHFTGVVDLVKMKAINWNDADQGVTFEYEDIPADMVELANEW
                     HQNLIESAAEASEELMEKYLGGEELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQ
                     AMLDAVIDYLPSPVDVPAINGILDDGKDTPAERHASDDEPFSALAFKIATDPFVGNLT
                     FFRVYSGVVNSGDTVLNSVKAARERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVT
                     TGDTLCDPDAPIILERMEFPEPVISIAVEPKTKADQEKMGLALGRLAKEDPSFRVWTD
                     EESNQTIIAGMGELHLDIIVDRMKREFNVEANVGKPQVAYRETIRQKVTDVEGKHAKQ
                     SGGRGQYGHVVIDMYPLEPGSNPKGYEFINDIKGGVIPGEYIPAVDKGIQEQLKAGPL
                     AGYPVVDMGIRLHFGSYHDVDSSELAFKLAASIAFKEGFKKAKPVLLEPIMKVEVETP
                     EENTGDVIGDLSRRRGMLKGQESEVTGVKIHAEVPLSEMFGYATQLRSLTKGRASYTM
                     EFLKYDEAPSNVAQAVIEARGK"
     gene            complement(2491..2961)
                     /gene="rpsG"
                     /locus_tag="IRB70_003441"
     CDS             complement(2491..2961)
                     /gene="rpsG"
                     /locus_tag="IRB70_003441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015873274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBC0633309.1"
                     /translation="MPRRRVIGQRKILPDPKFGSELLAKFVNILMVDGKKSTAESIVY
                     SALETLAQRSGKSELEAFEVALENVRPTVEVKSRRVGGSTYQVPVEVRPVRRNALAMR
                     WIVEAARKRGDKSMALRLANELSDAAENKGTAVKKREDVHRMAEANKAFAHYRW"
     gene            complement(3058..3432)
                     /gene="rpsL"
                     /locus_tag="IRB70_003442"
     CDS             complement(3058..3432)
                     /gene="rpsL"
                     /locus_tag="IRB70_003442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005306278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBC0633310.1"
                     /translation="MATVNQLVRKPRARKVAKSNVPALEACPQKRGVCTRVYTTTPKK
                     PNSALRKVCRVRLTNGFEVTSYIGGEGHNLQEHSVILIRGGRVKDLPGVRYHTVRGAL
                     DCSGVKDRKQARSKYGVKRPKA"
     gene            complement(3558..3845)
                     /gene="tusB"
                     /locus_tag="IRB70_003443"
     CDS             complement(3558..3845)
                     /gene="tusB"
                     /locus_tag="IRB70_003443"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusB"
                     /protein_id="HBC0633311.1"
                     /translation="MLHTLHRSPWLTDFAALLRLLSEGDELLLLQDGVTAGVDGNCYL
                     ESLRNAPIKVYALNEDLIARGLTGRISNDIIPIDYTDFVRLTVKHSSQMAW"
     gene            complement(3853..4212)
                     /gene="tusC"
                     /locus_tag="IRB70_003444"
     CDS             complement(3853..4212)
                     /gene="tusC"
                     /locus_tag="IRB70_003444"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusC"
                     /protein_id="HBC0633312.1"
                     /translation="MKRIAFVFSTAPHGTAAGREGLDALLATSALTDDLAVFFIADGV
                     FQLLPGQKPDAVLARDYIATFKLLGLYDIEQCWVCAASLRERGLDPQTPFVVEATPLE
                     ADALRRELANYDVILRF"
     gene            complement(4212..4598)
                     /gene="tusD"
                     /locus_tag="IRB70_003445"
     CDS             complement(4212..4598)
                     /gene="tusD"
                     /locus_tag="IRB70_003445"
                     /EC_number="2.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase complex subunit TusD"
                     /protein_id="HBC0633313.1"
                     /translation="MRFAIVVTGPAYGTQQASSAFQFAQALIAEGHELSCVFFYREGV
                     YNANQLTSPASDEFDLVRGWQQLNAQHGVALNICVAAALRRGIVDETEAGRLGLASSN
                     LQSGFTLSGLGALAEASLTCDRVVQF"
     gene            complement(4598..5320)
                     /locus_tag="IRB70_003446"
     CDS             complement(4598..5320)
                     /locus_tag="IRB70_003446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBC0633314.1"
                     /translation="MSRSLLTNETSELDLLDQRPFDQTDFDILKSYEAVVDGLAMLIG
                     SHCEIVLHSLQDLKCSAIRIANGEHTGRKIGSPITDLALRMLHDMTGADSSVSKCYFT
                     RAKSGVLMKSLTIAIRNREQRVIGLLCINMNLDVPFSQIMSTFVPPETPDVGSSVNFA
                     SSVEDLVTQTLEFTIEEVNADRNVSNNAKNRQIVLNLYEKGIFDIKDAINQVADRLNI
                     SKHTVYLYIRQFKSGDFQGQDK"
     gene            complement(5487..6299)
                     /gene="fkpA"
                     /locus_tag="IRB70_003447"
     CDS             complement(5487..6299)
                     /gene="fkpA"
                     /locus_tag="IRB70_003447"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBC0633315.1"
                     /translation="MKSLFKVTLLATTMAVALHAPITFAAEAAKPATTADSKAAFKND
                     DQKSAYALGASLGRYMENSLKEQEKLGIKLDKDQLIAGVQDAFADKSKLSDQEIEQTL
                     QAFEARVKSSAQAKMEKDAADNEAKGKEYREKFAKEKGVKTSSTGLVYQVVEAGKGEA
                     PKDSDTVVVNYKGTLIDGKEFDNSYTRGEPLSFRLDGVIPGWTEGLKNIKKGGKIKLV
                     IPPELAYGKAGVPGIPPNSTLVFDVELLDVKPAPKADAKPEADAKAADSAKK"
     gene            6520..6738
                     /locus_tag="IRB70_003448"
     CDS             6520..6738
                     /locus_tag="IRB70_003448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein SlyX"
                     /protein_id="HBC0633316.1"
                     /translation="MQDLSLEARLAELESRLAFQEITIEELNVTVTAHEMEMAKLRDH
                     LRLLTEKLKASQPSNIASQAEETPPPHY"
     gene            complement(6788..7378)
                     /gene="slyD"
                     /locus_tag="IRB70_003449"
     CDS             complement(6788..7378)
                     /gene="slyD"
                     /locus_tag="IRB70_003449"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBC0633317.1"
                     /translation="MKVAKDLVVSLAYQVRTEDGVLVDESPVSAPLDYLHGHGSLISG
                     LETALEGHEVGDKFDVAVGANDAYGQYDENLVQRVPKDVFMGVDELQVGMRFLAETDQ
                     GPVPVEITAVEDDHVVVDGNHMLAGQNLKFNVEVVAIREATEEELAHGHVHGAHDHHH
                     DHDHDGCCGGHGHDHGHEHGGEGCCGGKGNGGCGCH"
     gene            complement(7473..7673)
                     /locus_tag="IRB70_003450"
     CDS             complement(7473..7673)
                     /locus_tag="IRB70_003450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheV family putative metal-binding protein"
                     /protein_id="HBC0633318.1"
                     /translation="MAIRKRFIAGAKCPACQAQDSMAMWRENNIDIVECVKCGHQMRE
                     ADKEARDHVRKDEQVIGIFHPD"
     gene            complement(7683..9489)
                     /gene="kefB"
                     /locus_tag="IRB70_003451"
                     /pseudo
     CDS             complement(7683..9489)
                     /gene="kefB"
                     /locus_tag="IRB70_003451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417809.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     protein KefB"
     gene            complement(9489..10040)
                     /gene="kefG"
                     /locus_tag="IRB70_003452"
     CDS             complement(9489..10040)
                     /gene="kefG"
                     /locus_tag="IRB70_003452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312229.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-regulated potassium-efflux system
                     ancillary protein KefG"
                     /protein_id="HBC0633319.1"
                     /translation="MSQPAKVLLLYAHPESQDSVANRVLLKPATQLSNVTVHDLYAHY
                     PDFFIDIPREQALLREHEVIVFQHPLYTYSCPALLKEWLDRVLSRGFASGPGGNQLAG
                     KYWRSVITTGEPESAYRYDALNRYPMSDVLRPFELAAGMCRMHWLSPIIIYWARRQSA
                     QELASHARAYGDWLANPLSPGGR"
     gene            10171..12084
                     /locus_tag="IRB70_003453"
     CDS             10171..12084
                     /locus_tag="IRB70_003453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0633320.1"
                     /translation="MIVFSSLQIRRGVRVLLDNATATINPGQKVGLVGKNGCGKSTLL
                     ALLKNEISADGGSYTFPGSWQLAWVNQETPALPQAALEYVIDGDREYRQLEAQLHDAN
                     ERNDGHAIATIHGKLDAIDAWSIRSRAASLLHGLGFSNEQLERPVSDFSGGWRMRLNL
                     AQALICRSDLLLLDEPTNHLDLDAVIWLEKWLKSYQGTLILISHDRDFLDPIVDKIIH
                     IEQQSMFEYTGNYSSFEVQRATRLAQQQAMYESQQERVAHLQSYIDRFRAKATKAKQA
                     QSRIKMLERMELIAPAHVDNPFRFSFRAPESLPNPLLKMEKVSAGYGDRIILDSIKLN
                     LVPGSRIGLLGRNGAGKSTLIKLLAGELAPVSGEIGLAKGIKLGYFAQHQLEYLRADE
                     SPIQHLARLAPQELEQKLRDYLGGFGFQGDKVTEETRRFSGGEKARLVLALIVWQRPN
                     LLLLDEPTNHLDLDMRQALTEALIEFEGALVVVSHDRHLLRSTTDDLYLVHDRKVEPF
                     DGDLEDYQQWLSDVQKQENQADEAPKENANSAQARKDQKRREAELRAQTQPLRKEIAR
                     LEKEMEKLNAQLAQAEEKLGDSELYDQSRKAELTACLQQQASAKSGLEECEMAWLEAQ
                     EQLEQMLLEGQSN"
     gene            12084..13106
                     /locus_tag="IRB70_003454"
     CDS             12084..13106
                     /locus_tag="IRB70_003454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBC0633321.1"
                     /translation="MAQITTTDANEFSSSAEFSPMRGFSNCHLQTMLPRLFRRKVKFT
                     PYWQRLELPDGDFVDLAWSEDPAQARHKPRLVVFHGLEGSLNSPYAHGLVEAAQKRGW
                     LGVVMHFRGCSGEPNRMNRIYHSGETEDASWFLRWLQREFGHAPTAAVGYSLGGNMLA
                     CLLAKEGTDLPIDAAVIVSAPFMLEACSYHMEKGFSRIYQRYLLNLLKANAARKLAAY
                     PGTLPINLAQLKSVRRIREFDDLITARIHGYADAIDYYRQCSAMPMLNQIAKPTLIIH
                     AKDDPFMDHQVIPKPESLPPQVEYQLTEHGGHVGFIGGTLLHPQMWLESRIPDWLTTY
                     LEAKSC"
     gene            13100..13318
                     /locus_tag="IRB70_003455"
     CDS             13100..13318
                     /locus_tag="IRB70_003455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YheU family protein"
                     /protein_id="HBC0633322.1"
                     /translation="MLIPWQDLSPETLENLIESFVLREGTDYGEHERTLEQKVADVKR
                     QLQCGEAVLVWSELHETVNIMPRSQFRE"
     gene            13372..14241
                     /locus_tag="IRB70_003456"
     CDS             13372..14241
                     /locus_tag="IRB70_003456"
                     /EC_number="2.7.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribulokinase"
                     /protein_id="HBC0633323.1"
                     /translation="MSAKHPVIAVTGSSGAGTTTTSLAFRKIFAQLNLHAAEVEGDSF
                     HRYTRPEMDMAIRKARDAGRHISYFGPEANDFGLLEQTFIEYGQSGKGKSRKYLHTYD
                     EAVPWNQVPGTFTPWQPLPEPTDVLFYEGLHGGVVTPQHNVAQHVDLLVGVVPIVNLE
                     WIQKLIRDTSERGHSREAVMDSVVRSMEDYINYITPQFSRTHLNFQRVPTVDTSNPFA
                     AKGIPSLDESFVVIHFRNLEGIDFPWLLAMLQGSFISHINTLVVPGGKMGLAMELIML
                     PLVQRLMEGKKIE"
     gene            complement(14296..14700)
                     /locus_tag="IRB70_003457"
     CDS             complement(14296..14700)
                     /locus_tag="IRB70_003457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OsmC family protein"
                     /protein_id="HBC0633324.1"
                     /translation="MQARVKWVEGLTFLGESASGHQILMDGNSGDKAPSPMEMVLMAA
                     GGCSAIDVVSILQKGRQDVVDCEVKLTSERREEAPRLFTHINLHFIVTGRDLKDAAVA
                     RAVDLSAEKYCSVALMLEKAVNITHSYEVVAA"
     gene            15002..15634
                     /gene="crp"
                     /locus_tag="IRB70_003458"
     CDS             15002..15634
                     /gene="crp"
                     /locus_tag="IRB70_003458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cAMP-activated global transcriptional regulator
                     CRP"
                     /protein_id="HBC0633325.1"
                     /translation="MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIV
                     KGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRAKTACEVAEISYKK
                     FRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
                     PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR"
     gene            15685..17775
                     /locus_tag="IRB70_003459"
     CDS             15685..17775
                     /locus_tag="IRB70_003459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312236.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBC0633326.1"
                     /translation="MWRRLIYHPDINYALRQTLVLCLPVAVGLMLGELRFGLLFSLVP
                     ACCNIAGLDTPHKRFFKRLIIGASLFATCSLLTQLLLARDVPLPFLLTGLTLVLGVTA
                     ELGPLHAKLLPASLLAAIFTLSLAGYMPVWEPLLIYALGTLWYGLFNWFWFWIWREQP
                     LRESLSLLYRELADYCEAKYSLLTQHTDPEKALPPLLVRQQKAVDLITQCYQQMHMLS
                     AQNNTDYKRMLRIFQEALDLQEHISVSLHQPEEVQKLVERSHAEEVIRWNAQTVAARL
                     RVLADDILYHRLPTRFTMEKQIGALEKIARQHPDNPVGQFCYWHFSRIARVLRTQKPL
                     YARDLLADKQRRMPLLPALKSYLSLKSPALRNAGRLSVMLSVASLMGTALHLPKSYWI
                     LMTVLLVTQNGYGATRLRIVNRSVGTVVGLIIAGVALHFKIPEGYTLTLMLITTLASY
                     LILRKNYGWATVGFTITAVYTLQLLWLNGEQYILPRLIDTIIGCLIAFGGTVWLWPQW
                     QSGLLRKNAHDALEAYQDAIRLILSEDPQPTPLAWQRMRVNQAHNTLYNSLNQAMQEP
                     AFNSHYLADMKLWVTHSQFIVEHINAMTTLAREHRALPPELAQEYLQSCEIAIQRCQQ
                     RLEYDEPGSSGDANIMDAPEMQPHEGAAGTLEQHLQRVIGHLNTMHTISSMAWRQRPH
                     HGIWLSRKLRDSKA"
     gene            complement(17838..19061)
                     /gene="argD/dapC"
                     /locus_tag="IRB70_003460"
     CDS             complement(17838..19061)
                     /gene="argD/dapC"
                     /locus_tag="IRB70_003460"
                     /EC_number="2.6.1.11"
                     /EC_number="2.6.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001765220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     acetylornithine/succinyldiaminopimelate transaminase"
                     /protein_id="HBC0633327.1"
                     /translation="MAIEQTAITRATFDEVILPIYAPAEFIPVKGQGSRIWDQQGKEY
                     VDFAGGIAVTALGHCHPALVNALKTQGETLWHISNVFTNEPALRLGRKLIEATFAERV
                     VFMNSGTEANETAFKLARHYACVRHSPFKTKIIAFHNAFHGRSLFTVSVGGQPKYSDG
                     FGPKPADIIHVPFNDLHAVKAVMDDHTCAVVVEPIQGEGGVTAATPEFLQGLRELCDQ
                     HQALLVFDEVQCGMGRTGDLFAYMHYGVTPDILTSAKALGGGFPISAMLTTAEIASAF
                     HPGSHGSTYGGNPLACAVAGAAFDIINTPEVLEGIQAKRQRFVDHLQKIDQQYDVFSD
                     IRGMGLLIGAELKPQYKGQARDFLYAGAEEGVMMLNAGPDVMRFAPSLVVEDADIDEG
                     MHRFAHAMAKVIGGK"
     gene            complement(19147..19710)
                     /gene="pabA"
                     /locus_tag="IRB70_003461"
     CDS             complement(19147..19710)
                     /gene="pabA"
                     /locus_tag="IRB70_003461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 2"
                     /protein_id="HBC0633328.1"
                     /translation="MILLIDNYDSFTWNLYQYFCELGADVLVKRNDALTLADIDALKP
                     QKIVISPGPCTPDEAGISLDVIRHYVGCLPILGVCLGHQAMAQAFGGKVVRAAKVMHG
                     KTSPITHSGEGVFRGLANPLTVTRYHSLVVEPNSLPACFEVTAWSETREIMGIRHRQW
                     DLEGVQFHPESILSEQGHQLLANFLHR"
     gene            complement(19742..20344)
                     /locus_tag="IRB70_003462"
     CDS             complement(19742..20344)
                     /locus_tag="IRB70_003462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative adenosine monophosphate-protein
                     transferase Fic"
                     /protein_id="HBC0633329.1"
                     /translation="MSDKFGEGRDPYLYPGLDIMRNRLNIRQQQRLEQAAYEMTALRA
                     ATIELGPLVRGLPHLRTIHRQLYQDIFDWAGQLREVDIYQGDTPFCHFAYIEKEGNAL
                     MQDLEEEGYLVGLKKAKFVERLAHYYCEINVLHPFRVGSGLAQRIFFEQLAIHAGYQL
                     SWQGIEKEAWNQANQSGAMGDLTALQMIFSKVVSEAGESE"
     gene            complement(20334..20501)
                     /locus_tag="IRB70_003463"
     CDS             complement(20334..20501)
                     /locus_tag="IRB70_003463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhfG family protein"
                     /protein_id="HBC0633330.1"
                     /translation="MKKLTDKQKSRLWELQRNRNFQASRRLEGVEMPLVTLTAAEALA
                     RLEALRGHYER"
     gene            complement(20606..21178)
                     /gene="ppiA"
                     /locus_tag="IRB70_003464"
                     /gene_synonym="rotA"
     CDS             complement(20606..21178)
                     /gene="ppiA"
                     /locus_tag="IRB70_003464"
                     /gene_synonym="rotA"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase A"
                     /protein_id="HBC0633331.1"
                     /translation="MFKSTLAAMAAVFALSALSPAAMAAKGDPHVLLTTSAGNIELEL
                     DKQKAPVSVQNFVDYVNSGFYNNTTFHRVIPGFMIQGGGFTEQMQQKKPNPPIKNEAD
                     NGLRNTRGTIAMARTADKDSATSQFFINVADNAFLDHGQRDFGYAVFGKVVKGMDVAD
                     KISQVPTHDVGPYQNVPSKPVVILSAKVLP"
     gene            21449..22630
                     /gene="tsgA"
                     /locus_tag="IRB70_003465"
     CDS             21449..22630
                     /gene="tsgA"
                     /locus_tag="IRB70_003465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter TsgA"
                     /protein_id="HBC0633332.1"
                     /translation="MTNSNRIKLTWISFLSYALTGALVIVTGMVMGNIADYFNLPVSS
                     MSNTFTFLNAGILISIFLNAWLMEIVPLKTQLRFGFLLMVLAVAGLMFSHSLALFSAA
                     MFILGVVSGITMSIGTFLVTQMYEGRQRGSRLLFTDSFFSMAGMIFPMIAAFLLARSI
                     EWYWVYACIGLVYVAIFILTFGCEFPALGKHAPKTDAPVAKEKWGIGVLFLSIAALCY
                     ILGQLGFISWVPEYAKGLGMSLNDAGTLVSNFWMSYMVGMWAFSFILRFFDLQRILTV
                     LAGLAAILMYVFNTGTPAHMAWSILALGFFSSAIYTTIITLGSQQTKVPSPKLVNFVL
                     TCGTIGTMLTFVVTGPIVEHSGPQAALLTANGLYAVVFVMCFLLGFVSRHRQHNTLTS
                     H"
BASE COUNT         5566 a         6198 c         5628 g         5428 t
ORIGIN      
        1 tattcaacgt gagaagtgtt gatggtgata ccacgagctt tttcttccgg cgcgttatcg
       61 atctggtcga atgcacgagc agcaccgccg taggttttag ccagtacggt ggtgattgca
      121 gcggtcagag tagttttacc gtggtcaacg tggccgatag taccaacgtt aacgtgcggt
      181 tttgtacgtt caaatttttc tttagacacg gctatattcc ttactatagt gctctcccct
      241 tcaggagaga gcacgggact ttggtattaa cccttaggct tatttaccac gggcttcaat
      301 tacggcctga gcaacgttac tcggcgcttc atcatacttc aggaattcca tggtgtatga
      361 tgcacgacct ttggtcagag aacgcagctg agttgcatat ccgaacattt cagacagcgg
      421 tacttcagcg tggatcttaa cgccagtaac ttcagattcc tgacctttga gcataccacg
      481 acgacggctc aagtcaccga taacgtcacc ggtgttctct tccggagttt ctacttcaac
      541 cttcatgatc ggctcaagca gaactggttt cgctttctta aagccttctt taaaggcgat
      601 agaagcagcc agtttaaacg ccagttcaga ggagtcaacg tcatggtaag aaccgaagtg
      661 cagacgaata cccatgtcta ctaccgggta gcctgccagc ggacctgctt tcagctgttc
      721 ctggatacct ttatcaacgg ccgggatgta ttcgccaggg attacaccac ctttaatgtc
      781 gttgatgaac tcgtagcctt tcgggtttga acccggctcc agcgggtaca tgtcgataac
      841 aacatgacca tactgaccac gaccaccaga ctgtttcgcg tgtttacctt caacatcggt
      901 aactttctgg cggatagttt cacggtaagc aacctgcggt ttacctacgt tcgcttcaac
      961 gttgaattca cgcttcatac ggtcaacgat gatgtcgagg tgcagttcgc ccatacccgc
     1021 gatgatggtc tggttagatt cttcgtcagt ccatacacgg aaagacgggt cttctttagc
     1081 cagacggccc agagccagac ccattttttc ctggtcagct ttggttttcg gttcaactgc
     1141 gatggagatt accggctcag ggaattccat acgttccaga atgatcggcg catccgggtc
     1201 acacagggtg tcaccagtgg ttacgtcttt cagaccgatt gcagcagcga tgtcgcccgc
     1261 gcgaacttct ttgatctctt cacgtttgtt agcgtgcatc tgaacgatac gaccgaaacg
     1321 ctcacgtgca gctttcacgg agttcagtac ggtatcacca gagttaacca caccggagta
     1381 aacacggaag aaggtcaggt taccaacaaa cgggtcagta gcgattttga acgccagtgc
     1441 agagaacggc tcgtcatcac ttgcgtgacg ttcagccgga gtatctttac cgtcgtccag
     1501 gataccgttg atcgcaggta cgtcaaccgg ggatggcagg taatcaatta ccgcatccag
     1561 catcgcctga acacctttgt tcttgaacgc agaaccacag gttaccagga tgatttcgtt
     1621 gttcagaacg cgctgacgca gagcaccttt gatttctgct tcagtcagtt cttcaccacc
     1681 caggtatttt tccatcagct cttcagaagc ttcagctgcg gattcgatca ggttctggtg
     1741 ccattcgtta gccagttcaa ccatgtctgc cgggatatct tcgtattcga aggttacgcc
     1801 ctggtcagcg tcgttccagt tgatagcttt cattttcacc aggtcaacaa caccggtgaa
     1861 atgttcttca gcaccaatcg ccagctgcag cggaaccggg ttcgcgccca gacgggtttt
     1921 gatctggtta acaactttca ggaagttcgc acccatgcgg tccattttgt taacgaacgc
     1981 aatgcgcgga actttatatt tgtttgcctg acgccatacg gtttcagact gcggctgaac
     2041 accaccaact gcgcagtaaa ccattaccgc accatcgaga acacgcatgg aacgttctac
     2101 ttcgattgtg aagtcaacgt gccccggggt gtcgatgatg ttgatgcgat gcggctcata
     2161 ctgcttagcc ataccagacc agaatgcagt agtcgcagcg gaagtgatgg taataccacg
     2221 ttcctgctcc tgctccatcc agtccatggt tgcagcgccg tcatgaactt caccgatttt
     2281 atggtttaca ccggtgtaga acagaatacg ttcggtagta gtggttttac cggcgtcgat
     2341 gtgcgcactg ataccgatgt tacggtagcg tgcgatgggt gttgtacgag ccatttgttt
     2401 cctcgtttat cttttaggcg ttcaatttaa gtagcccaaa gcgggctgct tactggaagc
     2461 gcccgcctgg tgactaaaac tccgaaggga ttaccaacgg tagtgtgcga acgccttgtt
     2521 ggcttcggcc atacggtgaa cgtcttcacg tttcttaact gcagtacctt tgttttctgc
     2581 agcatcagaa agttcgttcg ccaggcgcag agccatggat ttatcaccgc gtttacgagc
     2641 agcttcaacg atccaacgca ttgccagagc attacgacga accggacgga cttcaactgg
     2701 tacctgataa gtagaaccac caacgcggcg agacttaact tctacagtcg ggcgcacgtt
     2761 ttcgagagct acttcgaatg cttccagttc agatttacca gagcgctgag ccagggtctc
     2821 cagcgcgctg tatacgatag attcagcagt agatttttta ccatctacca tcaggatatt
     2881 tacaaattta gccagcagtt ctgatccgaa cttcggatcc ggcagaattt tacgctgacc
     2941 aatgacgcga cgacgtggca tggaaatact ccgttgttaa ttcaggattg tccaaaactc
     3001 tacgagttta gtttgacatt taagttaaaa cgtttggcct tacttaacgg agaaccatta
     3061 agccttagga cgcttcacgc catacttgga acgagcctgc ttacggtctt taacgccgga
     3121 gcagtcaagc gcaccacgta cggtgtggta acgaacaccc gggaggtctt taacacgacc
     3181 gccacggatc aggatcacgg agtgctcctg caggttgtga ccttcaccac cgatgtagga
     3241 agtcacttcg aaaccgttag tcagacgaac acggcatact ttacgcagcg cggagttcgg
     3301 ttttttagga gtggtagtat atacacgagt acatacgcca cgtttttgcg ggcatgcttc
     3361 cagcgcaggc acgttgcttt tcgcaacttt gcgagcacgt ggtttgcgta ccagctggtt
     3421 aactgttgcc attaaatagc tcctggtttt agcttttgct tcgtaaacac gtaataaaac
     3481 gtcctcacac aatatgagga cgccgaattt tagggcgatg ccgaaaaggt gtcaagaaat
     3541 atacaacgat cccgccatca ccaggccatc tggctggagt gcttaaccgt aagtctgacg
     3601 aaatcagtat agtcaatggg aatgatgtcg ttcgaaattc gaccagtcaa accgcgggca
     3661 ataaggtctt cgttcagggc atagacctta atgggggcat tacgcagact ttcaaggtag
     3721 cagttaccgt caactccggc agttacgcca tcttgcaata atagcagttc gtcgccttca
     3781 ctgagcagac gcagcagcgc agcaaaatcc gtcagccagg gtgaacgatg taatgtatgc
     3841 agcataaacg cctcaaaacc tcaaaataac atcgtagttg gcgagttcgc ggcgtaaggc
     3901 atctgcttcg agcggcgtgg cttcgacaac aaagggtgtc tgcggatcta acccgcgttc
     3961 gcgcagtgaa gccgcacaaa cccagcactg ttcaatgtcg tacagaccca acaatttaaa
     4021 agtggcaatg taatcacgcg ccagcactgc atcgggcttt tgtcctggca gcagctgaaa
     4081 aacgccatca gctataaaga agacagccag atcgtcagtt aatgcggaag ttgccagtaa
     4141 agcatctaaa ccttcccggc ctgcagctgt accatgaggc gcagtagaaa aaacaaacgc
     4201 aattcgtttc atcagaactg taccaccctg tcacaggtca gcgaggcttc cgccagcgcg
     4261 ccaagtccgc ttaaggtaaa tcccgactga agatttgacg aagccagccc cagccttcct
     4321 gcttcagttt catcgacgat accgcggcgt aacgctgccg ctacgcagat attcagcgcc
     4381 acaccatgtt gcgcattcaa ctgttgccag ccgcgcacaa ggtcaaattc atcgcttgcc
     4441 ggtgaggtca attggttagc gttatagacc ccttcccgat agaaaaagac gcagcttaac
     4501 tcatggcctt cggctatcag tgcctgcgca aactgaaaag cactactcgc ctgttgcgta
     4561 ccgtatgctg gcccggtcac cacgatggca aaacgcatta cttatcttgc ccctggaaat
     4621 caccgctttt gaactggcgg atgtagagat agacagtgtg tttggagatg ttcaggcggt
     4681 cagcaacctg gttgatcgca tctttaatat cgaagatccc tttctcgtag agattcagca
     4741 cgatctgacg atttttggcg ttattagaaa cattgcgatc ggcattcact tcttcgatgg
     4801 tgaactccag cgtttgggta accagatctt caacagaaga ggcaaagttg acgcttgaac
     4861 cgacatccgg ggtttctggc ggcacaaagg tgctcataat ctgcgagaag ggaacatcaa
     4921 gattcatatt gatgcacagc agaccaatta cacgctgttc gcggttacga atcgcgatag
     4981 tcagggactt cattaatacg ccgcttttgg cgcgagtaaa gtagcattta gaaacgctgc
     5041 tatccgctcc cgtcatatcg tgcagcatac gtagcgccag gtcagtaatt ggcgaaccaa
     5101 tcttccggcc tgtatgttca ccgttagcaa tgcgaatggc tgaacatttt agatcctgca
     5161 aagagtgcaa aacgatttca cagtgggagc caataagcat cgctaacccg tccaccaccg
     5221 cttcgtagga tttcagaata tcaaaatcgg tctggtcgaa aggacgttga tccagtaaat
     5281 ccaactcact ggtttcgttg gttaaaagcg acctggacat gaaaaaaaac actccttttc
     5341 aggagcctgt cgttaacttt tcagggcagg ctcattaatg atgcgggtaa ctaaattaat
     5401 acagcggagg ttccgctttc cagcactaat tatatccggc ctgtaataaa aaaaccgccg
     5461 cctggtcagg cggcggttct taatgcttat tttttagcag aatctgcggc tttcgcatca
     5521 gcttccggct ttgcatcagc cttcggcgct ggtttcacat ccagcagctc tacgtcaaac
     5581 accagggtag aattcggtgg aatccccgga acacccgctt tgccgtaagc cagttctggt
     5641 ggaataacca gtttgatctt accgcctttc ttgatgttct tcagaccttc tgtccaaccc
     5701 gggataacac cgtccagacg gaaagagagc ggttcaccac gggtgtaaga gttgtcgaac
     5761 tctttaccgt cgatcagcgt acctttgtag ttcacgacaa cagtatcgct gtctttcggt
     5821 gcttcgcctt taccggcttc tactacctga taaaccagac cagttgaaga ggttttcaca
     5881 cctttctctt tggcaaattt ctcgcggtac tctttacctt tcgcttcgtt atctgccgcg
     5941 tctttttcca tcttcgcctg agcagaagac ttcacgcgag cttcgaatgc ttgcagtgtc
     6001 tgttcgatct cttggtcgga gagtttgctc ttatcagcaa atgcatcctg aacaccagcg
     6061 atcagctgat ctttatccag tttgatgccc agtttttctt gttctttaag agagttttcc
     6121 atgtaacgac ccagcgaagc acccaatgca taagctgatt tctgatcgtc atttttgaac
     6181 gctgctttgc tgtcagcagt tgtagcaggt tttgcagctt cagcagcaaa agtgattggt
     6241 gcatgcaggg caacggccat tgtggtcgcc agcagcgtta ctttaaacag tgatttcatc
     6301 catatctcca ggatcggggc atctcacccc agggttaact attatcagaa gggtactata
     6361 aagcgttgtc gaacaaatct acatacagac acgccctatt atcatctatt ttcagactct
     6421 ttttgtttaa attagtttcg atgaccgcga aatgagtgct gtctcgggca gcaaagttaa
     6481 gtagaatccg cggcgaccat tcgacaaaag aggtgaatca tgcaggattt atcattggaa
     6541 gcacgcctgg cagagctgga gagccgattg gcttttcagg aaatcaccat tgaagaactg
     6601 aacgtcacgg tgaccgctca tgaaatggag atggcgaaac tgcgcgatca tctgcgtctg
     6661 ctgaccgaga agctaaaagc cagccagccg tcgaacatcg cgtcgcaggc tgaagaaacg
     6721 ccaccgccac attattgagg cgtaaaaaaa gcggggattc ccccgctttt ttgtcacttt
     6781 ttcggtatta gtggcaaccg caaccgccgt tacctttacc gccgcagcag ccttcgccac
     6841 cgtgttcatg accgtgatcg tggccatgac caccgcagca accgtcgtgg tcgtgatcgt
     6901 ggtgatgatc gtgtgcaccg tgaacgtggc catgagccag ttcttcttca gtcgcttcgc
     6961 gaatcgccac aacttcaacg ttgaatttca ggttctgacc ggccagcatg tggttaccat
     7021 caaccacgac gtgatcgtct tcaaccgcag tgatttcaac cggtaccgga ccctggtcgg
     7081 tttcagccag gaaacgcata cctacctgca gttcatcaac gcccataaat acgtctttag
     7141 gaacgcgttg caccaggttt tcgtcgtact gaccgtaagc gtcgttcgcg ccaacagcga
     7201 catcaaattt gtcgccaact tcgtgacctt ccagcgccgt ttccaggcca gagatcaggg
     7261 aaccgtgacc atgcaggtag tccagcggcg cactcaccgg agactcatca accaacacac
     7321 cgtcttctgt acgtacctga taggccaggc tgaccaccag gtcttttgct actttcatga
     7381 tatctcctga gcatgggaag aatagtggcg cagattgtag cggaattctg cagccgtgta
     7441 ctcactagct taaaaaaact cggcgcatat cgctagtccg gatgaaaaat cccgatcact
     7501 tgctcatctt tgcgaacgtg atcgcgggct tctttgtctg cttctcgcat ctgatgtccg
     7561 cacttaacac attcaacaat atcaatatta ttttcgcgcc acatcgccat tgaatcctgc
     7621 gcctgacagg ccgggcattt tgcccccgca ataaaacgtt ttcggattgc catctttacc
     7681 ctctactcaa attcatccca gccgtccagc tggcgtcgtt cttgttgcat ttcacgctgg
     7741 aaaatctctt ccagttcgcg tcgggcttcc ctggcgcgag aaatttgtac ggtatcggca
     7801 tgcattggga tgagctctcg caacatccgc atatccaggc gacgaaaatg cagctgcgcc
     7861 cgctgtgcct gatgcggatg catgccaagc gtgaccagcg tcttgcgtcc cagctctaac
     7921 gcactggaga atgtctcacg agaaaactgc gtcacccctg cctgtaataa ctcatgcgcc
     7981 tccacacgtc cgcgcgctcg cgcaagaata tgtaaatgcg gaaagtgctg ctggcatatt
     8041 tccaccagtt tcatggtgtc ttccggctcg ttacaggtaa tgacgataga ctcagcggcc
     8101 tctgcacccg cagaacgtaa aagatctacc tgcgtggcgt cgccgtaata aactttgtag
     8161 ccatatttac gcatcaggtt aacggcgctg atatcccgct ccagcacggt aatgcgcatt
     8221 ttatttgcca tcagcaaacg accaatcacc tgaccaaaac gcccaaagcc cacgacaatg
     8281 acctgcggtt tatcatcgtt gacccatggt ttttcgtctt cttcttccgg tccgttaaac
     8341 tggcgggata gccatttatc taccagcttc atcagcagcg gcgtggtcat catggaaagc
     8401 gtcaccgtca ccagcaacag cgccatctgg tcgccctgaa ataagcgttg tgaagaagcg
     8461 gtagaaaaga gcacaaaggc aaactcaccg ccctgactca acacgccagc aaactgcatc
     8521 cgctctgagc tacgcacgcc atacaatcgc gccagcagat acagcacgag aattttcacc
     8581 gccaccagca caaccacact tatcactacc cacaacagat gggtataaag caccccgagg
     8641 ttgagtgaca tgccgacaga gataaagaac aaaccgagca gcaagccttt gaagggatcg
     8701 atagccgttt ccagttcatg gcgatattca ctttccgcca gtagcacacc cgcaataaac
     8761 gtaccgagcg ccatcgacaa ccccagcgca tccataaaca atgcggaacc caacaccagc
     8821 agcagcgtcg cggcggtgaa cacttcccgc acaccagaag ctgcaataaa acggaatacc
     8881 ggacgcagta aatagcgccc gccaatcagc atgccgacaa acgccagcac cttcatgccg
     8941 atcttcatcc agtcgaaatg ttcgtctgcc gaacccgcca acaacggcac taacgccagt
     9001 gccgggatca ccgccagatc ctgaaacagc agaaccgaaa aacctagctg cccggattcg
     9061 ctgcgattca tccctttctc acgcatcagt tgcaacgcca ttgcggttga ggacatcgca
     9121 aggccaatac caccgaccac cgccgcctgc catgagaaat gggtcagcat caataatccc
     9181 gccagcaacg ccgcgcttaa cagcacctgt gccgcaccta cgccaaaaat cgaacgccgc
     9241 aattgccaaa gcttggaggg attcaactcc aggccgatga taaacatcag gaacaccacg
     9301 ccgagttccg aaaagtggag gatctcatcg acgtcgctaa taaaacccag cccccacggg
     9361 ccaatagcaa tccctgccag caaatatccc aacacagcgc caatccccag ccgcgatgcc
     9421 agcggcaccg cagccaccgc cgcgaagaga aacagcactc ctgcgagtaa aaaaatcgga
     9481 accttccatc agcggcctcc tggagacagc ggatttgcca gccagtcacc gtaggctctg
     9541 gcgtggctcg ccagctcctg tgcgctttgc cgtctcgccc agtaaataat gatgggactt
     9601 aaccaatgca tccggcacat gcccgccgcc agttcaaagg ggcgcagcac atcgctcatc
     9661 gggtagcgat tcaaggcgtc ataacggtaa gcactttccg gctcgccggt ggtaatcacg
     9721 ctacgccagt actttcccgc cagttggttt cctcccggcc cgctggcaaa accacggctt
     9781 aatacccggt ccagccactc tttcagtagc gccgggcagc tataggtata aagaggatgc
     9841 tgaaagacaa tcacctcgtg ctcgcgcagt aatgcctgct ctcgggggat atcaataaaa
     9901 aaatcgggat agtgcgcgta aaggtcgtgc acggtaacat tgctgagctg cgtagccggt
     9961 ttaagcagta cccggtttgc caccgagtcc tgagattccg gatgggcata cagcagcaaa
    10021 actttcgctg gctgagacat catccccctc ccggtatggt ttttgtgtat agtcgctgtt
    10081 ttgggctacc attgcgcccg gtgcggcagc tcgcccatac attacattat cataatgata
    10141 agttaacata gtctgaacat acggcgcctt atgattgttt tctcctcgtt acaaattcgt
    10201 cgcggcgtgc gcgtcctgct ggataatgcc accgccacca tcaaccccgg gcagaaagtc
    10261 ggcctggtgg gtaaaaacgg ctgtggtaaa tctaccctgc tggcattgct gaaaaatgaa
    10321 atcagcgccg acggcggcag ctacaccttt ccgggaagct ggcaactggc gtgggtgaat
    10381 caggaaacac cagcgctacc gcaagcggcg ctggaatatg tcattgacgg cgaccgtgaa
    10441 tatcgtcaac tggaagcgca gctacacgac gccaacgaac gtaacgacgg gcacgccatc
    10501 gccactattc atggcaagct ggatgctatt gacgcatgga gtattcgctc ccgtgccgcc
    10561 agcctgctgc acggcctcgg tttcagcaat gaacaactgg agcgcccggt aagtgatttc
    10621 tccggtggct ggcgtatgcg tcttaacctt gcccaggcgc tgatttgccg ttcagacttg
    10681 ctgctgctcg acgaaccgac taaccacctc gatctcgatg ccgttatctg gctggaaaaa
    10741 tggctgaaga gctatcaggg cacgctgatc ctgatctctc acgaccgcga cttcctcgat
    10801 ccgatcgttg ataaaattat tcatatcgaa caacaaagca tgttcgagta caccggcaac
    10861 tacagttcgt ttgaagtaca gcgcgccacc cgtttggcgc agcaacaagc gatgtatgaa
    10921 agccagcagg aacgcgtggc gcatctgcaa agttatatcg accgtttccg tgccaaagcc
    10981 accaaagcga agcaggccca gagccgtatt aagatgctgg agcgtatgga gctgattgcc
    11041 ccggcgcacg tcgacaaccc gttccgcttt agcttccgcg cgccggaaag cctgcctaat
    11101 ccgttattaa agatggaaaa agtcagcgca ggctatggtg atcgcattat tctcgactcg
    11161 attaaactga atctggtccc cggctcgcgc attggtctgc taggccgcaa cggcgcgggt
    11221 aaatcgacat taatcaaact gttagccggt gaacttgcgc cagtcagcgg tgaaattggt
    11281 ctggcgaaag ggatcaagct cggctacttc gcccagcatc aacttgaata cctgcgcgcc
    11341 gacgaatcgc ctattcaaca tctggcacgt ttagcgccgc aggagctgga acaaaaactg
    11401 cgtgattacc tcggcggctt tggtttccag ggcgataaag taaccgaaga aacgcgccgc
    11461 ttttccggtg gggaaaaagc ccgcctggtg ctggcattaa tcgtctggca gcgtccgaat
    11521 ctgctgctgc tcgacgaacc gactaaccac cttgacctcg acatgcgtca ggcactcact
    11581 gaagcattaa tcgagttcga aggcgcgctg gttgtcgttt cgcacgaccg tcatttgctg
    11641 cgttccacca ctgacgatct ctacctggtt cacgatcgta aagtcgaacc gttcgacggc
    11701 gatctggaag attatcaaca gtggttgagc gacgtacaaa agcaggaaaa ccaggccgac
    11761 gaagcgccaa aagagaacgc gaacagcgcc caggcacgta aagatcagaa acgtcgggaa
    11821 gcggagctgc gtgcgcaaac ccagccactg cgtaaagaga ttgcccgtct ggaaaaagag
    11881 atggagaagc tgaacgcgca actggcgcag gcggaagaga aactcggcga cagcgaactg
    11941 tacgatcaaa gccgtaaagc ggagttgacc gcctgcctgc aacagcaagc cagcgccaaa
    12001 tccggcctgg aagagtgcga aatggcgtgg ctggaagccc aggagcagct tgagcagatg
    12061 ctgctggaag gccaaagcaa ctgatggcgc agataacaac gaccgatgcc aatgaattta
    12121 gcagcagtgc tgaattctcc cctatgcgcg gctttagcaa ttgtcatcta caaaccatgc
    12181 tgccgcgtct gttccgtcgc aaggtgaaat tcaccccgta ctggcagcgg ctggagttgc
    12241 ccgacggcga ttttgtcgat ctcgcgtgga gtgaagatcc tgcacaggcg cggcataaac
    12301 cgcgtttagt cgtgtttcac gggctcgaag gcagtctcaa tagcccttac gcccacggtc
    12361 tggttgaggc ggcgcaaaag cgtggctggc tgggcgtggt gatgcatttt cgcggatgca
    12421 gcggtgaacc aaaccgtatg aaccgcattt accattcggg cgaaaccgaa gacgctagct
    12481 ggtttttacg ctggctgcaa cgcgaatttg gtcatgcgcc aacggctgcc gtcggctatt
    12541 cgctcggcgg taatatgctg gcctgtttgc tggcaaaaga aggtactgat ctcccgattg
    12601 atgcggcggt gattgtctct gcgccgttta tgctggaggc ctgtagttac catatggaaa
    12661 agggcttttc ccgcatttat cagcgttact tgctgaacct gttaaaagcc aatgccgcgc
    12721 gcaagctggc agcctacccc ggaacactgc cgattaatct cgcgcagtta aaatcggtac
    12781 gtcgcatccg tgaatttgac gatctcatca ccgccagaat tcacggctac gctgacgcta
    12841 tcgactatta tcgtcagtgt agcgccatgc cgatgctgaa ccagatcgcc aaaccgacgc
    12901 tgattattca cgccaaagac gatccgttta tggatcatca ggtgatcccg aaaccggaaa
    12961 gtctcccccc gcaggtggag tatcaactga ctgaacatgg cggtcatgtt ggctttattg
    13021 gcggtacgtt acttcatccg caaatgtggc tggagtcacg cattcctgac tggttaacaa
    13081 cgtatctgga ggcgaaatca tgttgattcc gtggcaagac ctctcccccg aaacgctgga
    13141 aaatttaatt gaaagctttg tgttacgtga aggcaccgat tatggtgaac atgagcgtac
    13201 acttgaacag aaagtcgccg acgtcaaacg ccagctacag tgcggagaag cggtgctggt
    13261 atggtcggag ctgcacgaaa cggtcaatat catgccgcgc agtcagtttc gcgaataacc
    13321 tgcaaccgtc ggcggacgag ataataatga tagctaagtc atggagttac tatgtctgcc
    13381 aaacatccgg tcattgcggt aacaggatcc agcggcgcgg ggaccaccac caccagcctc
    13441 gcgtttcgta aaatattcgc gcagttaaat ctgcatgcag ccgaggtgga aggtgacagt
    13501 tttcaccgtt acacccgccc ggaaatggac atggcgatcc gcaaagcgcg cgacgccggg
    13561 cggcatatca gctacttcgg ccccgaagcg aacgacttcg gcctgctgga acaaaccttc
    13621 attgaatacg gtcagagcgg caaagggaaa tctcgcaaat atctgcatac ctacgacgaa
    13681 gccgtaccgt ggaatcaggt accggggaca ttcaccccat ggcaaccttt accggaaccc
    13741 actgatgtac tgttttatga aggtttacac ggcggcgtcg tcacgccaca gcataacgtt
    13801 gcgcagcatg tggatttact ggtcggcgtg gtgcctatcg ttaaccttga gtggattcaa
    13861 aaattgatcc gcgacaccag cgagcgcggg cactcacgag aagcagtgat ggactcagta
    13921 gtgcgctcaa tggaagacta tatcaactac atcacaccgc agttttcccg cacccatctt
    13981 aacttccagc gcgttcccac cgtcgacacc tcaaacccgt tcgcggcaaa aggtatcccg
    14041 tcgctggatg aaagctttgt ggtgatccat tttcgtaatc tggaagggat cgatttcccc
    14101 tggctgctgg cgatgttgca gggctcattc atttcccaca tcaatacgtt agtggtgccc
    14161 ggcggcaaaa tgggtctggc aatggaatta attatgctgc cgctggtgca acgattgatg
    14221 gaaggaaaga aaatcgagta actctgctat tacgccggat aaaatactat ccggcttcac
    14281 aacgggatag ttaaatcacg cggcaaccac ttcatacgag tgagtaatat tcaccgcttt
    14341 ttccagcatc aacgccactg aacaatattt ctcagcagag agatcaaccg cacgcgcaac
    14401 cgctgcgtct ttcaggtcgc gaccggtgac gataaaatgc agattaatgt gcgtaaacag
    14461 gcgtggtgcc tcttcgcggc gttcagaggt caattttact tcacaatcga ccacatcctg
    14521 acgccctttt tgcaggatag aaaccacatc gatggcactg caaccccccg ccgccatcaa
    14581 caccatttcc atcggacttg gtgctttatc gcctgagttg ccgtccatta aaatctggtg
    14641 accagaggcg gattcgccca gaaaagttaa cccttcgacc cacttcactc gcgcttgcat
    14701 ttttgctact ccactgcgtc aattttcctg acagagtacg cgtactaacc aaatcgcgca
    14761 acggaaggcg acctgggtca tgctgaagcg agacaccagg agacacaaag cgaaagctat
    14821 gctaaaacag tcaggatgct acagtaatac attgatgtac tgcatgtatg caaaggacgt
    14881 cacattaccg tgcagtacag ttgatagccc cttcccaggt agcgggaagc atatttcggc
    14941 aatccagaga cagcggcgtt atctggctct ggagaaagct tataacagag gataaccgcg
    15001 catggtgctt ggcaaaccgc aaacagaccc gactctcgaa tggttcttgt ctcattgcca
    15061 cattcataag tacccatcca agagcacgct tattcaccag ggtgaaaaag cggaaacgct
    15121 gtactacatc gttaaaggct ctgtggcagt gctgatcaaa gacgaagagg gtaaagaaat
    15181 gatcctctcc tatctgaatc agggtgattt tattggcgaa ctgggcctgt ttgaagaggg
    15241 ccaggaacgt agcgcatggg tacgtgcgaa aaccgcctgt gaagtggctg aaatttcgta
    15301 caaaaaattt cgccaattga ttcaggtaaa cccggacatt ctgatgcgtc tgtctgcaca
    15361 gatggcgcgt cgtctgcaag tcacttcaga gaaagtgggc aacctggcgt tcctcgacgt
    15421 gacgggccgc attgcacaga ctctgctgaa cctggcaaaa caaccagatg ctatgactca
    15481 cccggacggt atgcaaatca aaattacccg tcaggaaatc ggtcagattg tcggctgttc
    15541 tcgtgaaacc gtgggacgca ttctgaagat gctggaagat cagaacctga tctccgcaca
    15601 cggtaaaacc atcgtcgttt acggcactcg ttaatcccgt cggagtggcg cgttacctgg
    15661 tagcgcgcca ttttgtttcc cccgatgtgg cgcagactga tttatcaccc cgatattaac
    15721 tatgcactgc gacaaacgct ggtgctatgt ttgcccgtgg ccgttgggtt aatgcttggc
    15781 gaattacgat tcggtctgct cttctccctc gttcctgcct gttgcaatat tgcgggcctt
    15841 gatacgcctc ataaacgttt tttcaaacgc ttaatcattg gtgcgtcgct gtttgccacc
    15901 tgtagcttgc tgacacagct actactggca agagatgttc ctctgccctt tttgctgacc
    15961 ggattaacgc tggtacttgg cgtcactgct gagctggggc cattgcacgc aaaattgctt
    16021 cccgcatcgc tgctcgccgc catttttacc ctcagtctgg cgggatacat gccggtctgg
    16081 gaaccgttgc tcatctatgc gctgggcact ttgtggtacg gattgtttaa ctggttttgg
    16141 ttctggatct ggcgcgaaca accgctacgc gagtcactaa gtctgctgta ccgtgaactg
    16201 gcagattact gtgaagccaa atacagcctg cttacccagc acaccgaccc tgaaaaagcg
    16261 ctgccaccgc tgctggtgcg ccagcaaaaa gcggtcgatt taattactca gtgctatcag
    16321 caaatgcata tgctttccgc gcaaaataat accgattaca agcggatgct gcgtattttc
    16381 caggaggcgc tggatttgca ggaacatatt tcggtcagtt tgcatcagcc ggaagaggtg
    16441 caaaagctgg tcgagcgtag ccatgcggaa gaagttatcc gctggaatgc gcaaaccgtc
    16501 gccgctcgcc tgcgcgtgct ggctgatgac attctttacc atcgcctgcc aacgcgtttt
    16561 acgatggaaa agcaaattgg cgcactggaa aaaatcgccc gccaacaccc ggataatccg
    16621 gttgggcaat tctgctactg gcatttcagc cgcattgccc gcgtgctgcg cacccaaaaa
    16681 ccgctctatg cccgtgactt actggccgat aaacagcggc gaatgccgtt acttccggcg
    16741 ctgaaaagtt atctgtcact aaagtctccg gcgctacgca atgccggacg actcagtgtg
    16801 atgttaagcg ttgccagcct gatgggcacc gcactgcatc tgccgaagtc gtactggatc
    16861 ctgatgacgg tattgctggt gacgcaaaat ggctatggcg caacccgtct gaggattgtg
    16921 aatcgctccg tgggaaccgt ggtcgggtta atcattgcgg gcgtggcgct gcactttaaa
    16981 attcccgaag gttacaccct gaccttgatg ctgattacca ccctcgccag ctacctgata
    17041 ttgcgcaaaa actacggctg ggcgacggtc ggttttacca ttaccgcagt gtataccctg
    17101 caactgttgt ggctgaacgg tgagcagtac atccttccgc gtcttatcga taccattatt
    17161 ggttgtttaa ttgctttcgg tggtactgtc tggctgtggc cgcagtggca gagcgggtta
    17221 ttgcgtaaga acgcccatga cgctttagaa gcctatcagg acgcgattcg cttgattctg
    17281 agcgaggacc cgcaacctac gccactggcc tggcagcgaa tgcgggtaaa tcaggcgcat
    17341 aatactctgt ataactcatt gaatcaggcg atgcaggaac cggcgtttaa cagccattat
    17401 ctggcagata tgaaactgtg ggtaacgcac agccagttta ttgttgagca tattaatgcc
    17461 atgaccacgc tggcgcggga acaccgggca ttgccaccgg aactggcaca agagtattta
    17521 cagtcttgtg aaatcgccat tcagcgttgt cagcagcgac tggagtatga tgaaccgggt
    17581 agttctggcg atgccaatat catggatgcg ccggagatgc agccgcacga aggcgcggca
    17641 ggtacgctgg agcagcattt acagcgggtt attggtcatc tgaacaccat gcacaccatt
    17701 tcgtcgatgg catggcgtca gcgaccgcat cacgggattt ggctgagtcg caagttgcgg
    17761 gattcgaagg cgtaatgcag gctaaaccat cggatacagc gttcacgccg catccgacat
    17821 cttttgcctg atgcgtctta tttaccccca atcaccttcg ccatcgcgtg ggcgaaacga
    17881 tgcatccctt catcgatatc cgcatcttcc accaccagcg acggcgcaaa acgcatcaca
    17941 tcaggcccgg cattcagcat cattacgcct tcctctgcac ccgcatacag gaaatcacgc
    18001 gcctgacctt tgtactgtgg tttcagctct gcgccaatca acagccccat accgcgaata
    18061 tcgctaaaca catcgtactg ctgatcgatc ttctgcaaat ggtcaacaaa acgctggcgt
    18121 ttcgcctgaa tgccttccag cacttcaggg gtattgatga tatcaaacgc cgcgcccgct
    18181 actgcacagg ccagaggatt accgccgtag gtggaaccgt gagaaccagg atgaaacgcg
    18241 gaagcaatct ccgccgtggt cagcatggcg ctaatcggga aaccgccacc taacgctttc
    18301 gcagaggtca gaatatccgg cgtcacgccg tagtgcatat aggcaaacag atcgccggtc
    18361 cgccccatcc cgcactgcac ttcatcaaac accaataatg cctgatgttg atcgcacagc
    18421 tcgcgcaagc cctgcaaaaa ctctggcgtc gctgccgtca cgccgccctc gccctgaatc
    18481 ggctcaacca ccaccgcaca ggtatggtca tccatcaccg cttttactgc gtgaagatcg
    18541 ttaaaaggca cgtggatgat gtctgccggt tttggcccaa agccgtcgga atattttggc
    18601 tgcccaccca ccgaaacggt aaacagcgag cgaccatgaa aagcgttatg gaaggcaata
    18661 attttggttt tgaacgggct atgacgcaca caggcgtaat ggcgtgccag tttaaaggcg
    18721 gtttcgttag cttccgtgcc ggagttcata aacaccacgc gttcggcaaa cgttgcctca
    18781 atcagtttac ggccaagacg cagcgccggc tcattggtga aaacgttact aatatgccac
    18841 agagtttcgc cctgggtttt taacgcgttc accagcgcag gatggcaatg gcccaacgcc
    18901 gtaactgcaa tgccacccgc gaaatcgaca tactccttgc cctgttgatc ccagattcgg
    18961 ctcccctgac cttttaccgg aataaactct gccggagcat aaatcggcag gatcacttca
    19021 tcgaaagtcg cgcgtgtaat tgctgtttgt tcaattgcca tctcatgatc accctgttac
    19081 gcataaacca atgtgaaatt ataatcacaa aatatgcata aaaaatcact taatagcaat
    19141 cagaaatcag cgatgcagga aattagccag cagttgatgt ccttgttcgc tgagaatact
    19201 ttctggatgg aactgcacac cttccagatc ccactggcga tggcgaatcc ccataatctc
    19261 gcgggtttcg ctccaggccg tcacttcaaa gcacgctggt aatgagttag gttccaccac
    19321 cagcgaatgg tagcgtgtca cggtaagtgg atttgccagc ccccgaaata cgccctcacc
    19381 gctatgtgta atcggcgagg ttttgccgtg catgaccttt gcggcgcgca caactttgcc
    19441 accaaatgcc tgcgccattg cctgatgacc gaggcaaacg ccaagaatcg gcaagcaccc
    19501 gacatagtgg cgaataacgt caagggagat cccggcttca tctggcgtac aggggccggg
    19561 tgagatgaca attttttgtg gtttaagggc gtcgatatcc gccagcgtca acgcatcgtt
    19621 gcgcttaacc agcacatccg cccccagttc acaaaagtac tggtagaggt tccaggtaaa
    19681 agaatcgtag ttatcaataa gcaggatcat ggcggctccg gtacgaaaga accgcgctat
    19741 tttactcaga ttccccggct tcgcttacca ctttgctaaa tatcatctgc agtgcggtga
    19801 gatcccccat tgccccactc tgatttgcct gattccaggc ctctttttcg ataccctgcc
    19861 agctcagttg gtagcccgca tgaatcgcta gttgctcgaa gaagatccgc tgtgccagac
    19921 cacttcccac ccggaaggga tgcagcacgt tgatttcaca atagtaatgc gccagccgct
    19981 cgacgaactt cgctttcttc aggccaacca gataaccttc ttcctccaga tcctgcatca
    20041 gggcattgcc ctctttttcg atataagcaa agtggcagaa cggcgtatct ccctgataaa
    20101 tatcgacttc gcgcagttgc cccgcccagt cgaaaatatc ctgatacagc tggcgatgga
    20161 tagtgcgcaa atgcggtaaa ccgcgcacca gcggaccaag ctcaatggtc gcagcacgta
    20221 gcgccgtcat ttcgtaagcg gcctgttcca gccgctgctg ctggcggatg ttcagccggt
    20281 tacgcatgat atcaaggcct ggataaagat acggatcgcg cccttcgccg aatttatcgc
    20341 tcatagtgcc ccctcagcgc ttcaagacgc gctaaagcct ctgcggcagt aagagtgact
    20401 aaaggcatct cgacgccttc aagacggcga ctggcctgga aattacgatt acgctgaagc
    20461 tcccagagac gggacttttg cttatcggtg agtttcttca cttgatgcct ccctgaacgt
    20521 gtccatttgc cacaagtata agcggcaaat ccgggttacg ccgggagagc agaagcgcgg
    20581 gcaagattgc ccgcgcgaga aatcattacg gcaggacttt agcggaaagg ataactaccg
    20641 gttttgacgg cacattctgg tacggaccaa cgtcatgagt cggcacctgg gaaatcttat
    20701 cggcaacgtc catgcctttc accactttac caaataccgc gtaaccgaaa tcacgctgac
    20761 catggtcaag gaaggcgtta tcggcaacgt tgataaagaa ctggctggtg gcgctgtctt
    20821 tgtcagcggt acgcgccatc gcgatggtgc cacgcgtgtt gcgcaggccg ttatcggctt
    20881 catttttgat tggcgggttt ggttttttct gctgcatctg ctcggtgaaa ccgccgccct
    20941 gaatcataaa gccaggaatg acgcggtgaa aggtagtgtt gttataaaaa ccactgttca
    21001 cataatcgac aaagttttgc acagacactg gcgctttttg tttatccagc tccagttcga
    21061 tgttaccagc tgaggttgtc aacaatacgt gcgggtcccc tttcgctgcc attgctgcgg
    21121 gagaaagagc agaaagagcg aaaacagcag ccatcgccgc cagggtcgat ttgaacatga
    21181 gatttcctta acaaacagag cagaaaaaaa gcaagtgaag agattctaaa tagccttcaa
    21241 gaacaaggcc atccctttac ctaattttac gtatctgaaa tatatgtaac ctgacggtca
    21301 ctttttattc cgtgatcaaa atcacctctt aaaatgcaat ttagcaaccg attgcaataa
    21361 aacatttaat cagatcacaa aatcgcctaa aatcgcccgc tcgcggcata gcccgctatg
    21421 ccattttatt tttgaacgca ggccaatcat gactaacagc aatcgcatca agctcacatg
    21481 gattagcttt ctttcctacg cactgaccgg tgcgttggtt attgtcaccg ggatggtgat
    21541 gggaaatatc gccgattatt tcaatctgcc tgtttccagt atgagtaata ccttcacctt
    21601 cctcaacgcc ggcattttaa tctctatctt cctcaacgcc tggctgatgg aaatcgtccc
    21661 gttgaaaacg cagttacgtt ttggctttct cctgatggtg ctggcggttg ccggtttgat
    21721 gttcagccac agcctggcac tgttctcggc ggcgatgttc attctcgggg tggtcagcgg
    21781 catcaccatg tcgattggta cattcctggt aacacaaatg tatgaaggac gtcagcgcgg
    21841 ttcacgcctg ttatttaccg actccttctt cagtatggcc gggatgattt tcccaatgat
    21901 cgccgcgttt ctgctggcgc gcagcattga gtggtactgg gtttatgcct gcatcgggct
    21961 ggtgtacgtc gctatcttta ttctgacctt cggctgtgag ttcccggcgc tgggtaaaca
    22021 tgcgccaaaa acggacgctc cggtagcgaa agaaaaatgg gggatcggcg tgctgtttct
    22081 ctccattgcg gcactgtgct acatcctcgg tcagttaggt tttatctcct gggtgcctga
    22141 gtatgccaaa ggcctgggca tgagcctgaa cgacgcgggc acgctggtga gtaacttctg
    22201 gatgtcatac atggtcggca tgtgggcgtt cagctttatt cttcgcttct ttgatttgca
    22261 acgcattctg accgtactgg ctggtctggc tgcgattctg atgtacgtct ttaacaccgg
    22321 aacaccggca catatggcgt ggtcaattct cgccctgggc ttcttctcca gcgcgatcta
    22381 taccaccatc atcactttgg gttcacagca gacaaaagta ccgtcgccaa aactggttaa
    22441 ctttgtcctg acctgcggga ccatcggtac tatgttgacc tttgtggtta ccggcccgat
    22501 tgttgaacat agcggtccgc aggcggcgct gctgacggca aacggtctgt acgctgtcgt
    22561 ctttgtgatg tgcttcctgt taggtttcgt cagccgtcac cgtcagcata acaccctgac
    22621 ctctcattaa ttgctcatgc cgggcggcac tatcgtcgtc cggccttttc ctctcttacc
    22681 gcgctacgta catctatttc tataaacccg ctcaatttgt ctgttttttg tacaaacatg
    22741 aaatgtcaga caattccgtg acttaagaaa atttatacaa atcagcaata tacctcttaa
    22801 ggagtatata aaggtgaatt
//
LOCUS       DADXDL010000076        22313 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.076, whole genome shotgun sequence.
ACCESSION   DADXDL010000076 DADXDL010000000
VERSION     DADXDL010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.076"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            94..687
                     /locus_tag="IRB70_003466"
                     /pseudo
     CDS             94..687
                     /locus_tag="IRB70_003466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349194.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecQ"
     gene            594..1889
                     /locus_tag="IRB70_003467"
     CDS             594..1889
                     /locus_tag="IRB70_003467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312307.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBC0633333.1"
                     /translation="MDADSSDSTVTPGRLPDGLSSCPCFYLGKKLMNLSANAQATLLL
                     TSDFSRAAASEYKPLSNSEWGKFALWLKHQRISPADLLVPQPQEKLTGWSDPRISQER
                     ILGLLARGHSLALAVDKWQRAGLWILTRGDADYPVRLKNRLRTDAPPVLFGCGNKALL
                     QAEGMAIVGSRDAPTADLRYTQQLAAKLAQQGICVISGGARGIDECAMASALEAGGTA
                     VGVLADSLLKTSTLVKWREGLIAGNLVLISPFYPEVRFTVGNAMARNKYIYCLAESAM
                     VVRAGMTGGTITGAMEALKHQWLPVQVKPNQDMQSANSRLVENGASWSTEQAENVTFR
                     LPDVTGLMYDKALRNAQPELFSLHEDDANYAVMPSHTPVDFYQLFVAELAILAKESIS
                     IERLASCTGLTIEQISVWLNRAEEEGRVIRLGEGHYQFR"
     gene            complement(1935..2528)
                     /gene="yhgN"
                     /locus_tag="IRB70_003468"
     CDS             complement(1935..2528)
                     /gene="yhgN"
                     /locus_tag="IRB70_003468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YhgN"
                     /protein_id="HBC0633334.1"
                     /translation="MNEIISAAVLLILIMDPLGNLPIFMSVLKHTEPKRRRAIMVREL
                     LIALLVMLVFLFAGEKILAFLSLRAETVSISGGIILFLIAIKMIFPSASGNSSGLPAG
                     EEPFIVPLAIPLVAGPTILATLMLLSHQYPNQMGHLVIALLLAWGGTFVILLQSSLFL
                     RLLGEKGVNALERLMGLILVMMATQMFLDGIRMWMKG"
     gene            2720..3823
                     /gene="asd"
                     /locus_tag="IRB70_003469"
     CDS             2720..3823
                     /gene="asd"
                     /locus_tag="IRB70_003469"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBC0633335.1"
                     /translation="MKNVGFIGWRGMVGSVLMQRMVEERDFDAIRPVFFSTSQLGQAA
                     PSFGGTTDTLQDAFDLEALKALDIIVTCQGGDYTNEIYPKLRESGWQGYWIDAASSLR
                     MKDDAIIILDPVNQDVITDGLNNGIRTFVGGNCTVSLMLMSLGGLFANDLVDWVSVAT
                     YQAASGGGARHMRELLTQMGHLYGHVADELATPSSAILDIERKVTTLTRSGELPVDNF
                     GVPLAGSLIPWIDKQLDNGQSREEWKGQAETNKILNTSSVIPVDGLCVRVGALRCHSQ
                     AFTIKLKKDVSIPTVEELLAAHNPWAKVVPNDREITMRELTPAAVTGTLTTPVGRLRK
                     LNMGPEFLSAFTVGDQLLWGAAEPLRRMLRQLA"
     gene            4096..6282
                     /gene="glgB"
                     /locus_tag="IRB70_003470"
     CDS             4096..6282
                     /gene="glgB"
                     /locus_tag="IRB70_003470"
                     /EC_number="2.4.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-alpha-glucan branching enzyme"
                     /protein_id="HBC0633336.1"
                     /translation="MSDRIDRDVINALIAGHFADPFSVLGMHKTTAGLEVRALLPDAT
                     DVWVIEPKTGRKLAKLECLDSRGFFSGVIPRRKNFFRYQLAVVWHGQQNLIDDPYRFG
                     PLIQEMDAWLLSEGTHLRPYETLGAHADTMDGVTGTRFSVWAPNARRVSVVGQFNYWD
                     GRRHPMRLRKESGIWELFIPGAHNGQLYKYEMIDANGNLRLKSDPYAFEAQMRPETAS
                     LICGLPEKVVQTEERKKANQFDAPISIYEVHLGSWRRHTDNNFWLSYRELADQLVPYA
                     KWMGFTHLELLPINEHPFDGSWGYQPTGLYAPTRRFGTRDDFRYFIDAAHAAGLNVIL
                     DWVPGHFPTDDFALAEFDGTNLYEHSDPREGYHQDWNTLIYNYGRREVSNFLVGNALY
                     WIERFGIDALRVDAVASMIYRDYSRKEGEWIPNEFGGRENLEAIEFLRNTNRILGEQV
                     SGAVTMAEESTDFPGVSRPQDMGGLGFWYKWNLGWMHDTLDYMKLDPVYRQYHHDKLT
                     FGMLYNYTENFVLPLSHDEVVHGKKSILDRMPGDAWQKFANLRAYYGWMWAFPGKKLL
                     FMGNEFAQGREWNHDASLDWHLLEGGDNWHHGVQRLVRDLNLTYRHHKAMHELDFDPY
                     GFEWLVVDDKERSVLIFVRRDKEGNEIIVASNFTPVPRHDYRFGINQPGKWREILNTD
                     SMHYHGSNAGNGGTVHSDEIASHGRQHSLSLTLPPLATIWLVREAE"
     gene            6279..8252
                     /gene="glgX"
                     /locus_tag="IRB70_003471"
     CDS             6279..8252
                     /gene="glgX"
                     /locus_tag="IRB70_003471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen debranching protein GlgX"
                     /protein_id="HBC0633337.1"
                     /translation="MTQLAIGKPAPLGAHYDGQGVNFTLFSAHAERVELCIFDANGQE
                     HRYDLPGHSGDIWHGYLPDARPGLRYGYRVHGPWQPAEGHRFNPAKLLIDPCARQIDG
                     EFKDNPLLHAGHNEPDYRDNAAIAPKCVVVVDHYDWEDDAPPRTPWGSTIIYEAHVKG
                     LTYLHPEIPVEIRGTYKALGHPVMINYLKQLGITALELLPVAQFASEPRLQRMGLSNY
                     WGYNPVAMFALHPAYACSPETALHEFRDAIKALHKAGIEVILDIVLNHSAELDLDGPL
                     FSLRGIDNRSYYWIREDGDYHNWTGCGNTLNLSHPAVVDYACACLRYWVETCHVDGFR
                     FDLAAVMGRTPEFRQDAPLFTAIQNCPVLSQVKLIAEPWDIAPGGYQVGNFPPLFAEW
                     NDHFRDAARRFWLHYDLPLGAFAGRFAASSDVFKRNGRLPSAAINLVTAHDGFTLRDC
                     VCFNHKHNEANGEENRDGTNNNYSNNHGKEGLGGTLDLVERRRDSIHALLTTLLLSQG
                     TPMLLAGDEHGHSQHGNNNAYCQDNQLTWLDWSQASSGLTAFTAALIHLRKRIPALME
                     NRWWEEGDGNVRWLNRYAQPLSTDEWQNGPKQLQILLSDRFLIAINATLEVTEIVLPA
                     GEWHAIPPFAGEDNPVITAVWQGPAHGLCVFQR"
     gene            8270..9565
                     /gene="glgC"
                     /locus_tag="IRB70_003472"
     CDS             8270..9565
                     /gene="glgC"
                     /locus_tag="IRB70_003472"
                     /EC_number="2.7.7.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate adenylyltransferase"
                     /protein_id="HBC0633338.1"
                     /translation="MVSLEKNDHLMLARQLPLKSVALILAGGRGTRLKDLTNKRAKPA
                     VHFGGKFRIIDFALSNCINSGIRRMGVITQYQSHTLVQHIQRGWSFFNEEMNEFVDLL
                     PAQQRMKGENWYRGTADAVTQNLDIIRRYKAEYVVILAGDHIYKQDYSRMLIDHVEKG
                     ARCTVACMPVPIEEASAFGVMAVDENDKIIEFVEKPANPPSMPNDPSKSLASMGIYVF
                     DADYLYELLEEDDRDENSSHDFGKDLIPKITEAGLAYAHPFPLSCVQSDPDAEPYWRD
                     VGTLEAYWKANLDLASVVPELDMYDRNWPIRTYNESLPPAKFVQDRSGSHGMTLNSLV
                     SGGCVISGSVVVQSVLFSRVRVNSFCNIDSAVLLPEVWVGRSCRLRRCVIDRACVIPE
                     GMVIGENAEEDARRFYRSEEGIVLVTREMLRKLGHKQER"
     gene            9565..10998
                     /gene="glgA"
                     /locus_tag="IRB70_003473"
     CDS             9565..10998
                     /gene="glgA"
                     /locus_tag="IRB70_003473"
                     /EC_number="2.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen synthase GlgA"
                     /protein_id="HBC0633339.1"
                     /translation="MQVLHVCSEMFPLLKTGGLADVIGALPAAQIADGVDARVLLPAF
                     PDIRRGVTDAQVVSRRDTFAGHITLLFGHYNGVGIYLIDAPHLYDRPGSPYHDTNLFA
                     YTDNVLRFALLGWVGAEMASGLDPFWRPDVVHAHDWHAGLAPAYLAARGRPAKSVFTV
                     HNLAYQGMFYAHHMNDIQLPWSFFNIHGLEFNGQISFLKAGLYYADHITAVSPTYARE
                     ITEPQFAYGMEGLLQQRHREGRLSGVLNGVDEKIWSPETDLLLASRYTRDTLEDKAEN
                     KRQLQIAMGLKVDDKVPLFAVVSRLTSQKGLDLVLEALPGLLEQGGQLALLGAGDPVL
                     QEGFLAAAAEYPGQVGVQIGYHEAFSHRIMGGADVILVPSRFEPCGLTQLYGLKYGTL
                     PLVRRTGGLADTVSDCSLENLADGVASGFVFEDSNAWSLLRAIRRAFVLWSRPSLWRF
                     VQRQAMAMDFSWQVAAKSYRELYYRLK"
     gene            11017..13464
                     /gene="glgP"
                     /locus_tag="IRB70_003474"
     CDS             11017..13464
                     /gene="glgP"
                     /locus_tag="IRB70_003474"
                     /EC_number="2.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycogen phosphorylase"
                     /protein_id="HBC0633340.1"
                     /translation="MNAPFTYSSPTLSVEALKHSIAYKLMFTIGKDPVVANKHEWLNA
                     TLFAVRDRLVERWLRSNRAQLSQETRQVYYLSMEFLIGRTLSNAMLSLGIYEDVQGAL
                     EAMGLNLEELIDEENDPGLGNGGLGRLAACFLDSLATLGLPGRGYGIRYDYGMFKQNI
                     VNGSQKESPDYWLEYGNPWEFKRHNTRYKVRFGGRIQQEGKKTRWIETEEILGVAYDQ
                     IIPGYDTDATNTLRLWSAQASSEINLGKFNQGDYFAAVEDKNHSENVSRVLYPDDSTY
                     SGRELRLRQEYFLVSSTIQDILSRHYQLHKTYDNLADKIAIHLNDTHPVLSIPEMMRL
                     LIDEHQFSWDDAFEVCCQVFSYTNHTLMSEALETWPVDMLGKILPRHLQIIFEINDYF
                     LKTLQEQYPNDTDLLGRASIIDESNGRRVRMAWLAVVVSHKVNGVSELHSNLMVQSLF
                     ADFAKIFPGRFTNVTNGVTPRRWLAVANPSLSAVLDEHLGRNWRTDLSLLNELQQHCD
                     FPMVNHAVHQAKLENKKRLAEYIAQQLNVVVNPKALFDVQIKRIHEYKRQLMNVLHVI
                     TRYNRIKADPDAKWVPRVNIFGGKAASAYYMAKHIIHLINDVAKVINNDPQIGDKLKV
                     VFIPNYSVSLAQLIIPAADLSEQISLAGTEASGTSNMKFALNGALTIGTLDGANVEML
                     DHVGADNIFIFGNTAEEVEELRRQGYKPREYYEKDEELHQVLTQIGSGVFSPEDPGRY
                     RDLVDSLINFGDHYQVLADYRSYVDCQDKVDELYERQEEWTAKAMLNIANMGYFSSDR
                     TIKEYADHIWHIDPVRL"
     gene            13590..15098
                     /locus_tag="IRB70_003475"
     CDS             13590..15098
                     /locus_tag="IRB70_003475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312299.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBC0633341.1"
                     /translation="MMQNGKWILTSLVMTFFGIPILAQFLAAVVAMLGAGLAAILEFC
                     NLLFTPTIYLLLNVFMLTLGALLLFFSGRVWAGDSAPEKREIAAWRQCFFLLPALLTL
                     IGWIIALHLADYQLRQMGAGWLADLMLPWLGVLLVSLVGGEYWWIVIIPVGTHISFSL
                     GYGWLTRHPLTGTSGLRCRNLLLFLLLLLGIVAGYQAHLYKQQNPGVGVRENIDIWAW
                     RPDKLNNRLTPLRGKPQIQFTQNWPRLDGATAAYPIYASAFYALSVIPEDFHVWDYLD
                     NSRTQEAYNKIVNGDADIIFVAQPSDGQKKRAEKSGVTLLYTPFAREAFVFIVNADNP
                     VNSLTEQQVRDIFSGAITNWRTVGGKDQEIQTWQRPEDSGSQTVMQSQVMKNVRMISP
                     QETEVASMMEGMIKVVAEYRNTNNAIGYTFRYYATQMNADKNIKLLAINGIAPTAENI
                     RNGKYPYIVDAFMVTRENTTSETQKLVEWFLTPQGQSLVEDVGYVPMYPTMK"
     gene            15124..16116
                     /locus_tag="IRB70_003476"
     CDS             15124..16116
                     /locus_tag="IRB70_003476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PstS family phosphate ABC transporter
                     substrate-binding protein"
                     /protein_id="HBC0633342.1"
                     /translation="MNKFTCVLLLGTALLAGCVDREGYYNSVREEDSHGLTSLRGQPE
                     LRYNDDWSRWPRVYGATALYPLYASAYYELVPEPKDKDRTSLAWQAYGLQQTRTAEAY
                     DSLIKGTATVIFVAQPSEGQKKRAEEAGVKLKYTAFAREAFVFIVDIKNPVNSLSEQQ
                     VKDIFSGKVSRWNKVGGGDESIKVWQRPEDSGSQTVMKGLVMQDTPMLPAKKSTVIDL
                     MGGLITEVADYQNTPSSIGYTFHYYVTRMNDNMLKMRKQIKLLAINGVAPTEENIRNG
                     TYPYIIHAYMVTHENPTLETQKFVDWFLSPQGQQLVEDVGYVPIYDASSESSGQ"
     gene            16119..16718
                     /locus_tag="IRB70_003477"
     CDS             16119..16718
                     /locus_tag="IRB70_003477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633343.1"
                     /translation="MNKIRLYIPPLILGFVIVPLLVWPTVVALAACVITLSFMGEILF
                     SIPLMFRRISLLEFQLGLLAEYALFFCAMCCVGWQFSCRTQSELKSRLHCWLVFAPVY
                     FWLLLWNIIFYVAPAQIALLENMRNFFLTIVWLPLNFFQFGSQPWTDFIGPISAQLGF
                     ALGYYCQWRSKNRSQRKKWGEWVMCLSFVTLGMIAWALR"
     gene            complement(16933..18438)
                     /gene="glpD"
                     /locus_tag="IRB70_003478"
     CDS             complement(16933..18438)
                     /gene="glpD"
                     /locus_tag="IRB70_003478"
                     /EC_number="1.1.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate dehydrogenase"
                     /protein_id="HBC0633344.1"
                     /translation="METKDLIVIGGGINGAGIAADAAGRGLSVLMLEAQDLACATSSA
                     SSKLIHGGLRYLEHYEFRLVSEALAEREVLLKMAPHIAFPMRFRLPHRPHLRPAWMIR
                     IGLFMYDHLGKRTSLPGSTGLRFGANSVLKPEIKRGFEYSDCWVDDARLVLANAQMVV
                     RKGGEVLTRTRATSARRENGLWIVEAEDIDTGKKYTWQARGLVNATGPWVKQFFDEGM
                     HLPSPYGIRLIKGSHIVVPRVHTQKQAYILQNEDKRIVFVIPWMDEFSIIGTTDVEYK
                     GDPKAVKIEESEINYLLKVYNAHFKKQLSRDDIVWTYSGVRPLCDDESDSPQAITRDY
                     TLDIHDENGKAPLLSVFGGKLTTYRKLAEHALEKLTPYYQGIGPAWTKESVLPGGAIE
                     GDRDDYAARLRRRYPFLTESLARHYARTYGSNSELLLGNAGAISDLGEDFGHEFYEAE
                     LKYLVDHEWVRRADDALWRRTKQGMWLNADQQSRVSQWLVEYTQQKLSLAS"
     gene            18628..18954
                     /gene="glpE"
                     /locus_tag="IRB70_003479"
     CDS             18628..18954
                     /gene="glpE"
                     /locus_tag="IRB70_003479"
                     /EC_number="2.8.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase GlpE"
                     /protein_id="HBC0633345.1"
                     /translation="MDQFECINVADAHQKLQEKEAVLVDIRDPQSFAMGHAAQAFHLT
                     NDTLGAFMRDNDFDTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAWQRQFPA
                     EVAYGA"
     gene            18999..19829
                     /gene="glpG"
                     /locus_tag="IRB70_003480"
     CDS             18999..19829
                     /gene="glpG"
                     /locus_tag="IRB70_003480"
                     /EC_number="3.4.21.105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease
                     GlpG"
                     /protein_id="HBC0633346.1"
                     /translation="MLMITSFANPRVAQAFVDYMATQGVILTIQQHNQSDVWLADESQ
                     AERVRAELARFLENPADPRYLAASWQSGHTDSGLHYRRYPFFAALRERAGPVTWVMMI
                     ACVVVFIAMQILGDQEVMLWLAWPFDPTLKFEFWRYFTHALMHFSLMHILFNLLWWWY
                     LGGAVEKRLGSGKLIVITLISALLSGYVQQKFSGPWFGGLSGVVYALMGYVWLRGERD
                     PQSGIYLQRGLIIFALIWIVAGWFDLFGMSMANGAHIAGLAVGLAMAFVDSLNARKRK
                     "
     gene            19846..20604
                     /locus_tag="IRB70_003481"
     CDS             19846..20604
                     /locus_tag="IRB70_003481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000815090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR family transcriptional regulator"
                     /protein_id="HBC0633347.1"
                     /translation="MKQTQRHNGIIELVKQQGYVSTEELVEHFSVSPQTIRRDLNELA
                     EQNLILRHHGGAALPSSSVNTPWHDRKATQTEEKERIARKVAEQIPNGSTLFIDIGTT
                     PEAVAHALLNHSNLRIVTNNLNVANTLMVKEDFRIILAGGELRSRDGGIIGEATLDFI
                     SQFRLDFGILGISGIDSDGSLLEFDYHEVRTKRAIIENSRHVMLVVDHSKFGRNAMVN
                     MGSISMVDAVYTDAPPPVSVMQVLTDHHIQLELC"
     gene            complement(20586..22184)
                     /gene="rtcR"
                     /locus_tag="IRB70_003482"
     CDS             complement(20586..22184)
                     /gene="rtcR"
                     /locus_tag="IRB70_003482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RtcR"
                     /protein_id="HBC0633348.1"
                     /translation="MRKTVAFGFVGTVLDYAGRGSQRWSKWRPSLCLCQQESLVINRL
                     ELLHDARSRSLFETLKRDIANVSPETKVVGVEIELHNPWDFEEVYACLHDFARGYAFQ
                     PEKEDYLIHITTGTHVAQICWFLLAEARYLPARLIQSSPPRKKEQPRGAGEVTIIDLD
                     LSRYNAIASRFAEERQQTLDFLKSGIATRNAHFNRMIEQIEKVAIKSRAPILLNGPTG
                     AGKSFLARRIFELKQARHQFSGAFVEVNCATLRGDTAMSALFGHVKGAFTGARESREG
                     LLRSANGGMLFLDEIGELGADEQAMLLKAIEEKTFYPFGSDRQVSSDFQLIAGTVRDL
                     RQLVVEGKFREDLYARINLWTFALPGLRQRQEDIEPNLDYEVERHASLTGDSVRFNTE
                     ARRAWLAFATSSQAAWRGNFRELSASVTRMATFATSGRITLEVVEDEINRLRYNWQES
                     RPSVLTQLLGAEAENIDLFDRLQLEHVIAICRQAKSLSAAGRQLFDVSRQGKASVNDA
                     DRLRKYLARFNLTWEAVQDQHSSS"
BASE COUNT         5290 a         5501 c         6002 g         5520 t
ORIGIN      
        1 gcacttttct ttcacccaat gggtgaaagc tgaatttcga aggaatgcat atttatcaag
       61 gctttgatta tgctttttga agtactgacg tagaatctag gtattaaaca cgctgacctg
      121 ccgttaaatc tcaataaaca ggtggcagct ggggctttta cgcaatacgg atttaaaggg
      181 aacttgcctg cgggtttaca aggatctacg gggcgaatcc tttctcgttg gggagattcc
      241 gggtggggaa agcaggtagc acaggagaaa aaaacggggc gcttaagtga tgagctggta
      301 gaagcatgtg cggaaatggt tcgccaacgc tggaatccgc atcctgaacc aacctgggta
      361 tgctgcgttc cttcattaag gcacctcgac ctggttcctg attttgcccg gcgactggcg
      421 gcgaaacttg gcttaccttt tattgatgcc attgaaaaag tcgtggacaa tccaccgcag
      481 aaaatgcagc aaaaccgttt tcaccagtgt caaaatctcg acggggcgtt tgtgattacc
      541 cctcctttga tgccaggtcc ggcgttgctg gttgatgata tcgtggattc tgcatggacg
      601 ctgacagttc tgacagcact gttacgccag gcaggttgcc cgacggttta tcctcttgcc
      661 cttgcttcta cctcggtaaa aaattgatga atctttcagc caatgcacaa gcgaccctcc
      721 tgctaaccag cgatttttct cgcgcggcgg cgagtgagta taaacctctt agtaatagcg
      781 aatgggggaa gtttgcatta tggctgaagc accaacgtat cagtcccgcc gatcttctgg
      841 tgccgcaacc gcaagagaaa cttacaggct ggagcgatcc gcgtatttct caggagcgta
      901 ttcttggctt gctggcgcgt ggtcatagtc tggcgttggc ggtagataag tggcaacgcg
      961 ccggtttatg gatcttaacc cgcggagatg ccgattatcc cgttcgcttg aaaaaccgat
     1021 tgcgaacgga tgcacctccc gttttatttg gctgcgggaa taaagcatta ctgcaagcgg
     1081 aaggtatggc gattgttggc tcgcgagatg ctccgactgc cgatttgcgc tatacccaac
     1141 aactggcagc gaaactggcc caacagggga tttgcgttat ctctggtggt gcgcgaggta
     1201 ttgatgaatg tgcaatggcg tcggcactgg aggccggggg aactgccgtt ggcgtattag
     1261 ctgatagctt gttaaaaacg agtacgttag tgaaatggcg tgaagggctt atagcaggca
     1321 acctggtgtt gatttcgccg ttttacccag aggtacgttt caccgtcggc aatgcgatgg
     1381 cgcgaaataa atatatttat tgccttgctg aaagcgcaat ggttgtacgt gcgggaatga
     1441 ccggtggaac gataaccggg gcgatggagg cattaaaaca tcagtggctg cctgtgcagg
     1501 ttaaaccaaa tcaggatatg caatcagcca attcacgatt agtagaaaat ggggcgtcat
     1561 ggagtactga acaggctgag aatgtgacgt tcagactgcc agacgttact gggctgatgt
     1621 atgacaaagc actccgtaac gctcaaccag aattgttttc gctgcacgaa gatgacgcaa
     1681 attacgcagt gatgccctcg catacccctg tcgattttta tcaacttttt gtggcggaac
     1741 tggcgatcct tgcaaaggaa tcgataagta ttgaaaggct ggcgtcttgt actggtttaa
     1801 ccatcgaaca aattagtgtg tggctgaacc gcgcagaaga agagggaagg gttatccgat
     1861 tgggcgaagg tcattatcag ttcaggtaat aaaacaggtg ccgcgtctgg ttgtgtgcag
     1921 cacctgtttg aaccttaccc cttcatccac attcgaatgc cgtcgaggaa catctgagtt
     1981 gccatcatca ccagaatcaa tcccatcagg cgttcaagtg cattcacccc tttctcgccc
     2041 agcagacgta aaaatagcga agactgtagc aggatgacaa aggtgccacc ccaggccagc
     2101 agcagagcaa ttaccagatg tcccatctga ttcgggtact gatgagacaa caacatcagc
     2161 gtggcgagaa tagtcggccc ggcgactaac ggaattgcca acggcacgat aaacggctct
     2221 tcacctgccg gaagcccgct gctatttcct gaagcgctgg ggaaaatcat cttaatggcg
     2281 atcagaaaca gaatgatgcc gccagaaatg gagacggttt ctgctcgcag gctgagaaat
     2341 gccagaattt tctcacccgc aaacaggaac accagcatca ccaggagagc aataagcaac
     2401 tctcgcacca tgattgcccg ccgtcttttc ggttcagtat gtttcagtac ggacatgaaa
     2461 ataggtaggt ttccgagcgg atccataatc aggatcaata aaactgctgc agaaatgatt
     2521 tcattcataa ctcaaattcc ctgataattg ccgcggactt tctgcgtgct aacaaagcag
     2581 gataagtcgc attactgatg gcttcgctat cattgattaa tttcacttgc gactttggct
     2641 gctttttgta tggtgaaaga tgtgccagga ggagaccggc acatttatac agcacacatc
     2701 tttgcaggaa aaaacgctta tgaaaaatgt tggttttatc ggctggcgcg gtatggtcgg
     2761 ctccgttctc atgcaacgca tggttgaaga gcgcgacttc gacgccattc gccctgtctt
     2821 cttttctact tctcagcttg gtcaggctgc gccgtctttt ggcggaacca ctgacacact
     2881 tcaggatgcc tttgatctgg aggcgctaaa ggccctcgat atcattgtga cctgtcaggg
     2941 cggcgattat accaacgaaa tctatccaaa gcttcgtgaa agcggatggc aaggttactg
     3001 gattgacgca gcatcatctc tgcgcatgaa agatgacgcc atcatcattc ttgaccccgt
     3061 caatcaggac gtcattaccg acggattaaa taatggcatc aggacttttg ttggcggtaa
     3121 ctgtaccgta agcctgatgt tgatgtcgtt gggtggttta ttcgccaatg atcttgttga
     3181 ttgggtgtcc gttgcaacct accaggccgc ttccggcggt ggtgcgcgac atatgcgtga
     3241 gttattaacc cagatgggcc atctgtatgg ccatgtggca gatgaactcg cgaccccgtc
     3301 ctctgctatt ctcgatatcg aacgcaaagt cacaacctta acccgtagcg gtgagctgcc
     3361 ggtagataac tttggcgtgc cgctggcggg tagcctgatt ccgtggatcg acaaacagct
     3421 tgataacggt cagagccgcg aagagtggaa agggcaggcg gaaaccaaca agatcctcaa
     3481 cacatcttcc gtaattccgg tagatggttt atgtgtgcgt gtcggggcat tgcgctgcca
     3541 tagccaggca ttcactatta aattgaaaaa agatgtgtct attccgaccg tggaagaact
     3601 gctggctgcg cacaatccgt gggcgaaagt tgttccaaac gatcgggaaa tcactatgcg
     3661 tgagctaacc ccagctgccg ttaccggcac gctgaccacg ccggtaggcc gtctgcgtaa
     3721 gctgaatatg ggaccggagt tcctgtcagc ctttaccgtg ggcgaccagc tgctgtgggg
     3781 ggccgcggag ccgctacgtc ggatgcttcg tcaactggcg taatctttat tcattaaatc
     3841 tggggcgcga tgccgcccct gctagtgcgt aatacaggag taagcgcaga tgtttcatga
     3901 tttaccggga gttaaataga gcattggcta ttctttaagg gtggcggaat acacgagtat
     3961 tcacagcctt acctgaagtg aggacgacgc agagaggatg cacagagtgc tgcgccgttc
     4021 aggtcaaaaa aatgtcacaa ccagaagtca aaaattcagt tggatggggt gacacaataa
     4081 aacaggaaga caagcatgtc cgatcgtatc gatagagacg tgattaacgc gctaattgca
     4141 ggccattttg cggatccttt ttccgtactg gggatgcata aaaccaccgc gggactggaa
     4201 gtccgtgccc ttttacccga cgctaccgat gtgtgggtga ttgaaccgaa aaccgggcgc
     4261 aaactcgcaa aactggagtg tctcgactca cggggattct ttagcggtgt cattccgcga
     4321 cgtaagaatt ttttccgcta tcagttggct gttgtctggc atggtcagca aaacctgatt
     4381 gatgatcctt accgttttgg tccgctaatc caggaaatgg atgcctggct attatctgaa
     4441 ggtactcacc tgcgcccgta tgaaacctta ggcgcgcatg cagatactat ggatggcgtc
     4501 acaggtacgc gtttttctgt ctgggctcca aacgcccgtc gggtctcggt ggttgggcaa
     4561 ttcaactact gggacggtcg ccgtcatccg atgcgcctgc gtaaagagag cggcatctgg
     4621 gaactgttta tccctggggc gcataacggt cagctctata aatacgagat gattgatgcc
     4681 aatggcaact tgcgtctgaa gtccgaccct tatgccttcg aagcgcaaat gcgcccggaa
     4741 accgcgtctc ttatttgcgg gctgccggaa aaggttgtac agactgaaga gcgcaaaaaa
     4801 gcgaatcagt ttgatgcgcc aatctctatt tatgaagttc acctgggctc ctggcgtcgc
     4861 cacaccgaca acaatttctg gttgagctac cgcgagctgg ccgatcaact ggtgccttat
     4921 gctaaatgga tgggctttac ccatctcgag ctactgccca ttaacgagca tcccttcgat
     4981 ggcagttggg gttatcagcc aaccggcctg tatgcaccga cccgccgttt tggtactcgc
     5041 gacgacttcc gttatttcat tgatgccgca cacgcagctg gtctgaacgt gattctcgac
     5101 tgggtgccag gccacttccc gaccgatgac tttgcgcttg ccgaatttga tggcacgaac
     5161 ttgtatgaac acagcgatcc gcgcgaaggc tatcatcagg actggaatac gctgatctac
     5221 aactatggtc gccgtgaagt cagtaacttc cttgtcggta acgcgcttta ctggatcgaa
     5281 cgttttggta ttgatgcgct gcgcgtcgat gcggtggcgt caatgattta ccgcgactac
     5341 agccgtaaag agggggagtg gatcccgaac gaatttggcg ggcgcgagaa tcttgaagcg
     5401 attgaattct tgcgtaatac caaccgtatt cttggtgagc aggtttccgg tgcggtgaca
     5461 atggcggagg agtctaccga tttccctggc gtttctcgtc cgcaggacat gggcggtctg
     5521 ggcttctggt acaagtggaa cctcggctgg atgcatgaca ccctggacta catgaagctc
     5581 gacccggttt atcgtcagta tcatcacgat aaactgacct tcgggatgct ctacaactac
     5641 actgaaaact tcgtcctgcc gttgtcgcat gatgaagtgg tccacggtaa aaaatcgatt
     5701 ctcgatcgga tgccgggcga cgcatggcag aaattcgcta acctgcgcgc ctactacggc
     5761 tggatgtggg cattcccggg caagaaattg ctgttcatgg ggaacgaatt tgcccagggc
     5821 cgcgagtgga accatgacgc cagcctcgac tggcatctgt tggaaggcgg cgataactgg
     5881 caccacggtg tccagcgtct ggtgcgcgat ctgaacctca cctaccgcca ccataaagca
     5941 atgcatgaac tggattttga cccgtacggc tttgaatggc tggtggtgga tgacaaagaa
     6001 cgctcggtgc tgatctttgt gcgtcgcgat aaagagggta acgaaatcat cgttgccagt
     6061 aactttactc cggtgccgcg tcatgattat cgcttcggca ttaaccagcc gggcaaatgg
     6121 cgtgaaatcc tcaataccga ttccatgcac tatcacggca gtaatgccgg caatggcggc
     6181 acggtacaca gcgatgagat tgccagccac ggtcgtcagc attcactaag cctgacacta
     6241 ccaccgctgg ccactatctg gctggttcgg gaggcagaat gacacaactc gccattggca
     6301 aacccgcacc cctcggcgcg cattacgacg gtcagggcgt caacttcaca cttttctccg
     6361 ctcatgccga gcgggtagaa ctgtgtatct ttgacgccaa tggccaggaa catcgctatg
     6421 acttgccagg gcacagtggc gacatttggc acggttatct gccggatgcg cgtccgggtt
     6481 tgcgttatgg ttatcgcgtt catggcccct ggcaacccgc cgaggggcat cgctttaacc
     6541 cggcgaagtt gttgattgat ccttgcgcgc ggcaaattga cggggagttt aaagataacc
     6601 cgctgctgca cgccggtcat aatgaacctg actatcgcga caacgccgcc attgcgccga
     6661 aatgcgtagt ggtggttgat cactatgact gggaggatga tgctccgccg cgcacgccgt
     6721 ggggcagtac catcatttat gaagcccatg tcaaaggatt aacgtacctg cacccggaga
     6781 tcccggtcga gatccgtggc acttataaag ccctggggca tccggtgatg atcaactatt
     6841 tgaaacagtt gggcattacc gcgctggaac tgctgccggt ggcgcagttt gccagtgaac
     6901 cacgtctgca acgcatgggg ctaagtaact actggggtta caacccggtg gcgatgtttg
     6961 cgctgcatcc ggcgtatgcc tgctccccag aaacggcgct gcatgagttt cgcgatgcaa
     7021 tcaaagcact gcataaagcg ggtatcgaag tcattcttga tatcgtgctc aaccatagcg
     7081 cggaactgga cctcgacggc ccgttattct ctctgcgtgg gatcgacaac cgtagctatt
     7141 attggataag agaagacggc gattatcaca actggaccgg ttgcggcaat acgctcaatt
     7201 tgagtcatcc ggcggtggtg gattatgcct gcgcctgcct gcgttattgg gtagaaacct
     7261 gccacgtcga tggtttccgc tttgatctgg cggcagtcat gggccgtacg ccagagttcc
     7321 gtcaggatgc gccgttgttt accgctatcc agaactgccc cgtgctctca caggtgaagt
     7381 taattgctga accgtgggat attgctcctg gtggttatca ggtgggaaat ttcccgccgc
     7441 tgtttgccga gtggaacgat catttccgcg atgctgcccg tcgtttctgg ctgcattatg
     7501 atttgcctct gggggcgttt gccgggcgtt ttgctgcctc cagcgatgtt tttaaacgta
     7561 atggtcgtct gccgagtgcc gcgattaatc tcgtcaccgc gcatgacggt tttacgcttc
     7621 gcgactgcgt ttgcttcaac cataaacaca atgaagcaaa cggagaagaa aatcgcgacg
     7681 ggaccaacaa caattacagt aacaatcatg gtaaagaagg gttaggcggt actcttgatc
     7741 tggttgaacg gcggcgcgac agcattcacg ccctgttaac aacgttgttg ctctcccagg
     7801 gtacgccgat gttactggcc ggtgacgaac atggtcacag ccagcatggc aataacaatg
     7861 cctactgtca ggataaccaa ttaacctggt tggactggtc gcaggcaagc agtggtttaa
     7921 ccgcatttac cgccgcgtta atccatctgc gcaagcgcat tcccgctttg atggagaatc
     7981 gctggtggga agaaggcgac ggcaatgtcc gttggctaaa tcgatatgct caacctttaa
     8041 gcacggatga gtggcaaaac gggccgaaac agctgcaaat tctgctctcg gatcgctttt
     8101 tgatcgcaat taacgccacg cttgaggtaa cagagattgt tttacctgct ggggagtggc
     8161 acgccattcc cccattcgct ggagaggata acccagtgat tacggctgtc tggcagggac
     8221 ctgcacacgg attgtgtgtg ttccagagat gataaaaaag gagttagtca tggttagttt
     8281 agagaagaac gatcacttaa tgttggcgcg ccagctgcca ttgaaatctg ttgccctgat
     8341 actggcggga ggacgtggta cccgcctgaa ggatttaacc aataagcgag caaaaccggc
     8401 cgtacacttc ggcggtaagt tccgcattat cgactttgcg ctgtctaact gcatcaactc
     8461 cgggatccgt cgtatgggcg tgatcaccca gtaccagtcc cacactctgg tgcagcacat
     8521 tcagcgcggc tggtcattct tcaatgaaga aatgaacgag tttgtcgatc tgctgccagc
     8581 acagcagaga atgaaagggg aaaactggta tcgcggcacc gcagatgcag ttacccaaaa
     8641 cctcgacatt atccgccgtt ataaagcgga atacgtggtg atcctggcgg gcgaccatat
     8701 ctacaagcaa gactactcgc gtatgcttat cgaccacgtc gaaaaaggcg cacgttgcac
     8761 cgttgcttgt atgccagtac cgattgaaga agcctccgca tttggcgtta tggcggttga
     8821 tgagaacgat aaaattatcg aattcgttga aaaacctgct aacccaccgt caatgccgaa
     8881 cgatccgagc aaatctctgg cgagtatggg tatctacgtc tttgacgccg actatctgta
     8941 tgaactgctg gaagaagacg atcgcgatga gaactccagc cacgactttg gcaaagattt
     9001 gattcccaag atcaccgaag ccggtctggc ctatgcgcat ccgttcccgc tctcttgcgt
     9061 acaatccgac ccggatgccg agccgtactg gcgcgatgtg ggtacgctgg aagcttactg
     9121 gaaagcgaac ctcgatctgg cctctgtggt gccggaactg gatatgtacg atcgcaattg
     9181 gccaattcgc acctacaatg aatcattacc gccagcgaaa ttcgtgcagg atcgctccgg
     9241 tagccacggg atgaccctta actcactggt ttccggcggt tgtgtgatct ccggttcggt
     9301 ggtggtgcag tccgttctgt tctcgcgcgt tcgcgtgaat tcattctgca acattgattc
     9361 cgccgtattg ttaccggaag tatgggtagg tcgctcgtgc cgtctgcgcc gctgcgtcat
     9421 cgatcgtgct tgtgttattc cggaaggcat ggtgattggt gaaaacgcag aggaagatgc
     9481 acgtcgtttc tatcgttcag aagaaggcat cgtgctggta acgcgcgaaa tgctacggaa
     9541 gttagggcat aaacaggagc gataatgcag gttttacatg tatgttcaga gatgttcccg
     9601 ctgcttaaaa ccggcggtct ggctgatgtt attggggcat tacccgcagc acaaatcgca
     9661 gacggcgttg acgctcgcgt actgttgcct gcatttcccg atattcgccg tggcgtgacc
     9721 gatgcgcagg tagtatcccg tcgtgatacc ttcgccggac atatcacgct gttgttcggt
     9781 cattacaacg gggttggcat atacctgatt gacgcgccgc atctctatga tcgtccggga
     9841 agcccgtatc acgataccaa cttatttgcc tataccgaca acgtattgcg ttttgcgctg
     9901 ctggggtggg ttggggcaga aatggccagt gggcttgacc cattctggcg tcctgatgtg
     9961 gtgcatgcgc acgactggca tgcaggcctt gcgcctgcgt atctggcggc gcgcgggcgt
    10021 ccggcgaagt cggtgtttac tgtgcacaac ctggcctatc aaggcatgtt ttatgcacat
    10081 cacatgaatg acatccaatt gccatggtca ttctttaata ttcatgggct ggaattcaac
    10141 ggacaaatct cttttctgaa ggccggtctg tactatgccg atcacattac ggcagtcagt
    10201 ccaacctacg ctcgcgagat caccgaaccg cagtttgcct acggtatgga aggtctgttg
    10261 caacagcgtc accgtgaagg gcgtctttcc ggcgtactga acggcgtgga cgagaaaatc
    10321 tggagtccag agacggactt actgttggcc tcgcgttaca cccgcgatac gttggaagat
    10381 aaagcggaaa ataagcgcca gttacaaatc gcaatggggc ttaaggttga cgataaagtg
    10441 ccgctttttg cagtggtgag ccgtctgacc agccagaaag gtctcgacct ggtgctggag
    10501 gccttaccgg gtcttctgga gcagggcggg caactggcgc tactcggcgc gggcgatccg
    10561 gtgctgcagg aaggtttcct tgcggcggca gcggaatacc ccggccaggt gggcgttcag
    10621 attggctatc acgaagcatt ttcgcatcgc attatgggcg gcgcggacgt cattctggtg
    10681 cccagccgtt ttgaaccgtg cggcttaacg caactttatg gattgaagta cggtacgctg
    10741 ccgttagtgc ggcgcaccgg tgggcttgct gatacggttt ctgactgttc tcttgagaac
    10801 cttgcagatg gcgtcgccag tgggtttgtc tttgaagata gtaatgcctg gtcgctatta
    10861 cgggctattc gacgtgcttt tgtactgtgg tcccgtcctt cactgtggcg gtttgtgcaa
    10921 cgtcaggcta tggcaatgga ttttagctgg caggtcgcgg cgaagtcgta ccgtgagctt
    10981 tactatcgct tgaaatagtt ttcaggaaac gcctatatga atgctccgtt tacatattca
    11041 tcgcccacgc ttagcgtaga agctcttaag cactctatcg cttacaagct gatgtttacg
    11101 attggcaagg acccggtcgt cgccaataaa catgaatggc tgaacgcaac gttatttgct
    11161 gtgcgcgatc gtctcgtgga gcgctggtta cgttcaaacc gtgcccagtt gtcgcaagaa
    11221 actcgtcagg tttactacct gtcgatggag tttttgattg gccgtacgct ttccaacgcc
    11281 atgttgtcgc taggaattta cgaagatgta cagggcgcac tggaagcgat ggggttaaat
    11341 ctcgaagagc tgattgatga agaaaatgac ccgggcctcg gtaacggtgg cctgggacgt
    11401 ctggcggctt gcttccttga ttctctggcg acgttagggt tgccggggcg cggttacggc
    11461 atccgctatg actacggtat gttcaagcag aacatcgtta acggtagcca gaaagagtcg
    11521 cctgactact ggctggaata cggtaacccg tgggaattca aacgccacaa cacgcgctat
    11581 aaagtccgtt ttggcggtcg cattcagcag gaaggtaaaa aaacgcgctg gattgaaacc
    11641 gaagagattc tgggagtagc ttacgatcag ataatcccag gttacgacac cgacgcgacc
    11701 aacacgttgc gtttgtggag tgcccaagcc agtagcgaaa ttaacctcgg taaattcaac
    11761 cagggcgact acttcgcggc agtggaagat aaaaaccact ccgagaacgt atctcgcgta
    11821 ctgtatccgg acgactccac ctactccggg cgtgagctgc gactgcgtca ggaatacttc
    11881 ctggtttcct cgaccattca ggacatttta agccgccatt atcagttgca taaaacctac
    11941 gataacctgg cggataaaat tgcgattcac ctcaacgata cccatccggt gctgtcgatt
    12001 cctgagatga tgcgtctgct gatcgatgag caccaattta gctgggacga cgcgtttgaa
    12061 gtgtgttgtc aggtcttctc ctacaccaac cacacgctaa tgagcgaggc gctggaaacc
    12121 tggccagtcg atatgctggg taaaattctg ccgcgtcacc tgcagatcat ctttgaaatc
    12181 aacgactatt tcctgaaaac tttgcaggaa cagtatccga acgataccga tctgctggga
    12241 cgggcgtcga tcatcgatga atccaacggt cgtcgtgtgc gtatggcttg gctggcggtt
    12301 gtggtgagcc acaaagttaa cggtgtatcg gagctgcact ctaacctgat ggtgcaatcg
    12361 ctatttgccg actttgcgaa aatcttcccg ggtcgtttca ccaacgtcac caacggtgtg
    12421 acgccgcgtc gctggctggc ggtagcgaac ccatcgcttt cagctgtgtt ggacgaacac
    12481 ctgggccgca actggcgcac cgaccttagt ctgcttaatg agctgcaaca acactgtgat
    12541 ttcccaatgg ttaatcacgc ggtgcatcag gcgaagctgg agaacaaaaa gcgtctggcg
    12601 gagtatatcg cccagcagct gaatgtggtg gtaaatccga aagcgctgtt cgatgtgcaa
    12661 atcaaacgta ttcacgaata caaacgtcaa ttgatgaatg tgttgcacgt gatcacccgc
    12721 tataaccgca tcaaggccga cccggatgcg aagtgggtac cgcgcgtgaa tatttttggc
    12781 ggtaaggcgg cttcggccta ttacatggcg aagcacatta ttcatttgat caatgacgta
    12841 gcgaaagtga tcaacaacga tccgcagatt ggcgacaagc tgaaagtcgt gttcatcccg
    12901 aactacagtg ttagcctggc gcagttgatc attccggcgg ccgatctatc tgaacagatt
    12961 tcgctggcgg ggacggaagc ttccggcacc agtaacatga agtttgcgct taacggcgcg
    13021 ctgactatcg gtacgctgga cggtgcgaat gtcgagatgc tggatcatgt cggtgctgac
    13081 aatatcttta tctttggtaa cacagcggaa gaagtggaag aactgcgtcg tcagggctac
    13141 aaaccgcgtg aatactacga gaaagatgag gagctgcatc aggtgctgac gcaaatcggc
    13201 agcggtgtat tcagtccgga agatccgggt cgctatcgcg atctggtcga ttcgctgatc
    13261 aacttcggcg atcactacca ggtactggcg gattatcgca gctatgtcga ttgtcaggat
    13321 aaagtcgacg aactctacga gcgtcaggaa gagtggaccg caaaagcgat gctgaacatt
    13381 gccaatatgg gctacttctc ttctgaccgt acgatcaaag agtacgccga tcatatctgg
    13441 catattgatc cggtgagatt gtaagttcgc taaaaaacag aacggggcca aaaggtcccg
    13501 ttttttttcg cctttattta ggaaaagtgt ccagaggggg cgagggttat cggggagtat
    13561 aatttcgcca ttcagcaaga atggaaagaa taatgcaaaa cggaaaatgg attttgacct
    13621 cgctggtaat gacttttttt ggcatcccca tactggcgca atttttggca gcggttgttg
    13681 ccatgctggg ggccgggctt gccgctattc ttgagttttg caatttactc tttacaccaa
    13741 caatttatct tctactcaac gtctttatgc tgacgctggg cgcattactg ctatttttct
    13801 ctggtcgcgt gtgggctggt gatagcgcac cagaaaaaag agaaatagcc gcctggcgac
    13861 aatgcttttt tctcttaccc gcgctattaa ccctgattgg ctggataatc gcgctacatc
    13921 tggcagatta tcaacttcgc cagatgggag ccggttggtt ggcagatctt atgcttccct
    13981 ggctgggtgt tttgttagtc tcattagtcg gtggtgagta ctggtggata gtcattattc
    14041 ccgttggaac gcatatcagt ttttcgctgg gatacggctg gctgacaagg catcctttaa
    14101 ccggcacgtc cgggctacgt tgccgtaact tactcctgtt tctacttctc ttacttggta
    14161 ttgtcgctgg gtatcaggcc catttatata agcagcaaaa ccctggtgtt ggtgtacgcg
    14221 aaaatattga tatctgggcc tggcgacccg ataaacttaa taatcgactg acgccactgc
    14281 gtggtaaacc acaaattcaa tttacgcaaa actggccgcg actcgatggc gctacggcgg
    14341 cgtaccccat ttatgcctct gcattttatg cattaagtgt aataccagag gattttcacg
    14401 tttgggatta tctggataac tctcgtacgc aagaagcata taacaaaatc gttaacggtg
    14461 atgccgatat tattttcgtg gcgcaacctt ccgatgggca aaaaaaacgc gctgagaaat
    14521 cgggcgtcac tttgctgtac acgccatttg cccgtgaagc gtttgttttc atcgtcaatg
    14581 cggataatcc ggttaattcc ctgactgaac aacaagtgcg agacattttt agtggcgcaa
    14641 ttaccaactg gcgcacggtt ggcggtaagg atcaggagat ccagacctgg caacgcccgg
    14701 aagactctgg cagccagaca gtgatgcaat cacaggtcat gaaaaatgtc cgcatgatct
    14761 cgccgcagga aaccgaagtg gcaagcatga tggagggaat gattaaagtc gttgccgaat
    14821 accgtaatac aaacaacgca ataggctaca ccttccgcta ttacgcaaca caaatgaatg
    14881 ccgataaaaa tataaaactg ctagcgatta acggtatagc accgactgcg gaaaatattc
    14941 gtaacggcaa atatccgtat atcgtcgatg cctttatggt aacgcgggaa aatactacgt
    15001 cagaaacaca aaaactggtc gaatggtttt taacgccgca ggggcagagt ttggtagaag
    15061 acgtgggtta tgtgccgatg tatccaacaa tgaaataacg ctcgagagaa aggaatcagc
    15121 gcaatgaata aattcacctg tgttttacta ttaggtacgg cgctactggc gggatgtgtc
    15181 gaccgggaag ggtactataa cagcgtcagg gaagaagaca gccatggact gacgtctctg
    15241 cgggggcaac ctgaattacg ttacaacgat gattggtcaa gatggccgag agtgtacggc
    15301 gctacagcct tatacccgct gtatgcctcc gcgtattatg aattagtacc cgagccaaaa
    15361 gataaggatc gaacctcgct ggcctggcag gcgtatggtt tgcaacaaac ccgaacagct
    15421 gaagcctacg atagtctgat taagggtacc gcgacggtta tttttgttgc acaaccgtcg
    15481 gaaggacaga aaaaacgtgc agaagaagca ggtgttaaac tcaaatatac cgctttcgcc
    15541 cgcgaagcct ttgtctttat cgttgatatc aaaaacccgg ttaattcact tagcgaacag
    15601 caggtcaaag acatttttag cggtaaagtg agtcgctgga ataaagtggg cggcggtgac
    15661 gaaagtataa aagtctggca gcggccagaa gattctggaa gccaaacggt tatgaaggga
    15721 ctggttatgc aagatactcc aatgctgcca gccaaaaaat ccactgttat cgatcttatg
    15781 ggcggtttaa ttaccgaagt cgccgactac caaaatacac catcttctat tggatacacc
    15841 ttccactatt acgtcacacg tatgaatgac aatatgctca aaatgcgcaa acagatcaaa
    15901 ctgctggcta taaatggcgt tgcacctaca gaggaaaata tccgtaacgg cacttatccg
    15961 tacataattc atgcttatat ggtgacgcac gaaaacccta cgctggaaac gcagaaattc
    16021 gtcgactggt ttttaagccc gcagggacag caattggtag aggatgtggg ctatgtgccg
    16081 atttatgacg catcatccga atcatcagga caataaagat gaataaaatc agactttata
    16141 ttcctccgtt aattcttggt tttgttattg tgccgttgtt ggtgtggccg acggtggttg
    16201 ctctggctgc ttgtgttatc acgctgagtt ttatgggaga aatactgttc tctatcccgc
    16261 tcatgttcag gcgtatttca cttctggaat tccaacttgg gttattggct gaatatgcac
    16321 tttttttctg tgccatgtgt tgcgttggtt ggcaattttc ttgcagaact caatctgaac
    16381 tgaaaagcag actccattgt tggttggtat ttgcaccagt ttatttctgg ttgctcctgt
    16441 ggaatatcat tttctatgtc gcgccagcgc aaattgcttt gctggaaaat atgcgcaatt
    16501 tctttctgac cattgtctgg ttacccctga atttttttca atttgggtct cagccgtgga
    16561 ctgactttat cggtccgata agcgcccagc ttggttttgc attgggatat tattgccagt
    16621 ggcgtagcaa aaatagaagt cagaggaaga agtggggcga gtgggtaatg tgtctgagtt
    16681 ttgttacgtt gggtatgatt gcgtgggctt tgcggtaatt ccttgaatca aaaagtaggt
    16741 cagattgttg acgaagtgcg ctttgtttat gccggatgct gcgtgaacgc cttattttgt
    16801 ctacaaaatc atgcaaattc aatatattgc ataaaccacg taggcctgat aagcgtagcg
    16861 catcaggcag tttttttgtt tatcatcagt ctcaggtcag attgaaatct gacctggcca
    16921 ccttacgtta atttacgacg ccagcgacaa cttctgctgc gtatactcca ccagccactg
    16981 actcacacga gattgttgat ccgcatttag ccacatgcct tgttttgtgc gacgccacag
    17041 ggcatcgtcg gcgcgacgga cccattcgtg atccaccagg tatttcagtt ccgcttcgta
    17101 gaactcatga ccgaaatctt ccccgaggtc gcttatcgct cccgcattgc cgagcagcag
    17161 ttcgctgttg ctgccgtaag tgcgtgcgta gtgacgtgcc agcgattcag tcaggaacgg
    17221 gtaacggcgg cgcaggcgag cggcataatc gtcgcggtcg ccttcaatgg cacctcccgg
    17281 cagcacgctc tctttcgtcc acgccgggcc aataccctga taatacggcg tcagtttttc
    17341 cagcgcatgt tccgccagtt tgcggtaggt ggtcagctta ccgccgaata ccgacagcag
    17401 cggggctttg ccgttttcat catggatatc aagggtgtaa tcacgggtaa tagcctgcgg
    17461 cgagtcggac tcatcatcac acagcggacg cacaccggaa taggtccaga cgatatcgtc
    17521 acggctaagc tgttttttaa agtgcgcgtt atacactttc agcaggtaat tgatttcact
    17581 ctcttcaatc ttcaccgctt tcggatcgcc tttgtattcc acatcggtgg tgccgatgat
    17641 ggaaaactcg tccatccacg ggatcacgaa cacaatacgt ttatcttcgt tttgcagaat
    17701 gtaggcttgc ttctgggtat gcacgcgtgg caccacaata tggctgcctt tgatcaggcg
    17761 aatgccataa ggcgaaggca gatgcatccc ctcgtcgaag aactgtttca cccacgggcc
    17821 ggtggcgttc accaggccgc gcgcctgcca ggtgtatttt ttgccggtat cgatatcttc
    17881 tgcttccaca atccacaggc cgttttcgcg gcgagcagac gtggcacgag tacgagtaag
    17941 cacttcaccg cctttacgta ccaccatctg ggcgttggcg agtaccagac gggcgtcgtc
    18001 tacccaacag tcagaatatt cgaatccgcg cttaatttcc ggttttaaca ctgagtttgc
    18061 gccaaaacgc aaaccggttg atcccggcag gctggtgcgt ttacccagat gatcgtacat
    18121 aaacagacca atgcgaatca tccacgccgg gcgcagatgc ggacgatgtg gcaggcgaaa
    18181 acgcatcggg aaggcgatat gcggagccat tttcagcaac acttcacgtt cagccagcgc
    18241 ctcgctgacc aggcggaatt catagtgctc aaggtagcgc aggccaccgt gaatgagttt
    18301 tgaactggcg gaagaggtcg cgcaagcgag atcctgcgcc tccagcatca gcacggataa
    18361 accgcgtcca gcggcgtctg ccgcgatacc agcaccattg atgccgccac ctatcacaat
    18421 cagatctttg gtttccatgc tgccctcatt cactttcgtt aaagttcata aatgttcgtt
    18481 atcgaacata ttagcaaaga atcgcgcttt gggtaacatt gaaaaaacat tttagagtga
    18541 tatgtataac attatggcgt ttatctgccg cttcgacgta aactgtgcgg taaatttgcc
    18601 cacttgtttg taaagaaaga gagacgcatg gatcagttcg aatgtattaa cgttgccgac
    18661 gcgcaccaga agttgcagga aaaagaggcg gtgctggtcg atattcgcga tccacagagt
    18721 ttcgcaatgg ggcatgcggc gcaggctttc catttaacca acgacacatt gggcgcgttt
    18781 atgcgtgata acgacttcga tacgccagtc atggtgatgt gttaccacgg taatagcagc
    18841 aaaggcgcgg cgcagtatct gctgcaacag ggctacgatg tggtctacag cattgatggc
    18901 ggctttgaag cctggcagcg ccagtttccc gcagaggtgg cgtacggcgc gtaacgcttt
    18961 atactgtccc cttttgtgtg gaataagcga cagcaacgat gttgatgatt acctcttttg
    19021 ctaatccccg agtggcgcag gcgtttgttg attacatggc gacgcagggt gttatcctca
    19081 cgattcaaca acataaccaa agcgatgtct ggctggcgga tgagtcccag gccgaacgcg
    19141 tgcgggcgga gctggcgcgt tttctcgaaa acccggcaga tccgcgttat ctcgccgcca
    19201 gttggcagtc cggtcatacc gacagtggcc tgcattatcg ccgttatcct ttctttgctg
    19261 ccttgcgtga acgcgcaggt ccggtaacct gggtgatgat gattgcctgc gtggtggtgt
    19321 ttatcgccat gcaaattctc ggcgatcagg aagtgatgtt atggctggcc tggccattcg
    19381 atccgacgct gaaatttgag ttctggcgtt acttcaccca cgcgttaatg cacttctcgc
    19441 tgatgcatat cctctttaac ctgctctggt ggtggtatct cggcggtgcg gtggaaaaac
    19501 gcctcggtag cggtaagcta attgtcatta cgcttatcag cgccctgtta agcggctatg
    19561 tgcagcaaaa attcagcggg ccgtggtttg gcgggctttc tggcgtggtg tatgcgctga
    19621 tgggctacgt ctggctacgt ggcgaacgcg atccgcaaag tggcatttac ctgcaacgtg
    19681 ggttaattat ctttgcgttg atctggattg tcgccggatg gtttgatttg tttgggatgt
    19741 cgatggcgaa cggagcacac atcgccgggt tagccgtggg tttagcgatg gcttttgttg
    19801 attcgctcaa tgcgcgaaaa cgaaaataat tccagggatt tagaaatgaa acaaacacaa
    19861 cgtcacaacg gtattatcga actggttaaa cagcagggtt atgtcagtac cgaggagctg
    19921 gtggagcact tctccgttag cccgcagact attcgccgcg atctcaacga gctggcagag
    19981 caaaacctga tcctgcgcca tcatggcggt gcggcgctgc cttccagttc ggttaatacg
    20041 ccgtggcacg atcgcaaggc cacccagacc gaagaaaaag agcgcatcgc ccgcaaagtg
    20101 gcggagcaaa ttcccaatgg ctcgacgctg tttatcgata tcggcaccac gccggaagcg
    20161 gtggcgcacg cgctgcttaa tcacagcaat ttgcgcattg tgaccaacaa tctcaacgtc
    20221 gctaacacgc tgatggtaaa agaagatttt cgcatcattc tcgccggtgg cgaattacgc
    20281 agccgcgatg gtgggatcat tggcgaagca acgctcgatt ttatctccca gttccgcctt
    20341 gatttcggca ttctggggat tagtggcatc gatagcgacg gttcgctgct ggagttcgat
    20401 taccacgaag ttcgcaccaa acgcgccatt attgagaact cgcgccacgt tatgctggtt
    20461 gtcgatcact cgaaatttgg ccgtaacgcg atggtcaata tgggcagtat cagcatggta
    20521 gatgccgtct acaccgacgc cccgccgcca gtaagcgtga tgcaggtgct gacggaccac
    20581 catattcaac tggagctgtg ctgatcctgc acggcttccc acgtcagatt aaaacgcgcc
    20641 aggtatttgc gtagccgatc cgcgtcgttg acgctggctt tcccttggcg cgaaacgtca
    20701 aaaagctggc gtccggcagc ggaaagcgac tttgcctgac ggcagatagc gataacgtgt
    20761 tccagttgca gtcgatcaaa gaggtcgatg ttttccgctt cagcgcccag tagctgtgta
    20821 agcacggaag ggcggctctc ctgccagtta tagcgcagac ggtttatctc atcttcaacc
    20881 acttccagag tgatgcgtcc gctagtggca aaggttgcca ttcgcgtgac gctggcagaa
    20941 agctcgcgaa agttaccgcg ccatgccgcc tgagatgatg ttgcaaaggc cagccaggcg
    21001 cgccgcgctt cggtgttaaa acgcacgctg tcgccggtaa gtgaggcgtg gcgctccact
    21061 tcataatcca ggttaggttc aatatcttcc tggcgctggc gtagccccgg cagagcgaaa
    21121 gtccagagat taatccgtgc gtacaggtct tcgcgaaatt tgccttcgac aaccagttgg
    21181 cgcaaatcgc gcaccgttcc ggcgataagc tgaaaatcgc tactcacctg gcgatcgctg
    21241 ccaaacgggt aaaaggtttt ctcttcaatg gctttcagca gcattgcctg ttcgtctgcg
    21301 cccagttcgc caatctcatc aagaaataac atcccgccgt tggcgctgcg taataatcct
    21361 tcccgcgact cccgcgcccc ggtaaacgcg cctttcacat gaccaaacag cgctgacatg
    21421 gcggtatcgc cgcgcagagt ggcacagttc acctccacaa acgcgccgct aaactgatgc
    21481 cgcgcctgtt ttaactcgaa gatgcgtcgt gccagaaacg actttcccgc accggttggg
    21541 ccgttgagca ggatcggtgc gcgggatttg atcgccactt tttcgatctg ctcaatcatg
    21601 cggttgaagt gggcgttacg cgtggcaatg ccggatttga ggaaatcgag ggtttgctgg
    21661 cgttcctcgg caaagcggct ggcgatggcg ttataacggc ttaaatcgag atcgataatc
    21721 gtcacttcac ctgcgccgcg cggttgttct tttttgcgcg gtggtgaaga ttgtatcaac
    21781 cgggcgggta gataacgcgc ttctgccagc agaaaccagc aaatctgcgc gacgtgggta
    21841 ccggtggtga tgtgaattaa atagtcttct ttttctggct ggaacgcgta accacgggcg
    21901 aaatcatgca ggcaggcgta aacctcttcg aaatcccacg ggttatgcag ttcaatctca
    21961 acgcccacca cttttgtttc tggcgaaaca ttggcgatat cgcgtttaag cgtttcaaac
    22021 agcgagcgtg agcgggcgtc gtgcaacaat tccagtcgat tgatgactaa cgattcttgc
    22081 tggcatagac agagtgacgg acgccatttc gaccagcgct gactgccgcg cccggcataa
    22141 tccagtacgg tgccgacaaa gccaaaagcc actgttttac gcatcttaga tatccttata
    22201 aaagacgata tttcattatc ggcgaattgg ctttgcggga aatctccgtt tacggacgta
    22261 aagatttaat ctattaaaaa caatgaatta aaaaattaag ctgcttattt aat
//
LOCUS       DADXDL010000077        22032 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.077, whole genome shotgun sequence.
ACCESSION   DADXDL010000077 DADXDL010000000
VERSION     DADXDL010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 22032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22032
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.077"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            34..204
                     /locus_tag="IRB70_003483"
     CDS             34..204
                     /locus_tag="IRB70_003483"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633349.1"
                     /translation="MSLATTVKESKLQRRMYTQQALMYRQKGDREGVRVFLNAAKTEV
                     LNQRYFLGPCPF"
     gene            215..820
                     /locus_tag="IRB70_003484"
     CDS             215..820
                     /locus_tag="IRB70_003484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000031374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ERF family protein"
                     /protein_id="HBC0633350.1"
                     /translation="MSKEFYARLAAIQENLNAPKNQYNSFGKYKYRSCEDILEGVKPL
                     LNGLFLSISDEVVLIGDRYYVKATATITDGENSHTATALAREEESKKGMDSAQVTGAT
                     SSYARKYCLNGLFGIDDAKDADTDEHKHQQNAAAKQSKPSPTPEQVLKAFTDAAMQKN
                     TVEELKQAFAKAWKMLEGTPEQHKAQDVYNIRRDELEGAAA"
     gene            820..1203
                     /locus_tag="IRB70_003485"
     CDS             820..1203
                     /locus_tag="IRB70_003485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000951334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633351.1"
                     /translation="MAHSITVRLNKPAREFQTGENIGFNIRAGVQYYDRQTKKKEWTN
                     YSAVVFAKPGAQADYYRSVLVEGGIVEITGENIRVDVYQGQNGQSITLELLNAKIGFA
                     ASGNGPQQQSSNQQNTPVYDDSIPF"
     gene            1227..1523
                     /locus_tag="IRB70_003486"
     CDS             1227..1523
                     /locus_tag="IRB70_003486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001111277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2856 family protein"
                     /protein_id="HBC0633352.1"
                     /translation="MPAPLYGADDPRRCSGNSVSEVLDKFRKNYDRIMSLPQETKEEK
                     EFRHCIWLAEKEERERIYQTSIRPFRKATYTNFPEYIDPRLRNYRSRYGAISND"
     gene            1534..1701
                     /locus_tag="IRB70_003487"
     CDS             1534..1701
                     /locus_tag="IRB70_003487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2737 family protein"
                     /protein_id="HBC0633353.1"
                     /translation="MRGLAYNPGILPAEMIIRQRVKPMPSREELLKRNSFPSVNQNKY
                     LNAMWRKGGNQ"
     gene            1698..1997
                     /locus_tag="IRB70_003488"
     CDS             1698..1997
                     /locus_tag="IRB70_003488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000118152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633354.1"
                     /translation="MTVCLIDKRRRGQQIPSVEMPNHTWFCVLDIDGMDTLIDTRHYC
                     ETATATPAKAKKMAALIENWTPPDGWCNGNDRDWHEKMKGYICDFLRKCNGFRVM"
     gene            1999..2721
                     /locus_tag="IRB70_003489"
     CDS             1999..2721
                     /locus_tag="IRB70_003489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001550160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ead/Ea22-like family protein"
                     /protein_id="HBC0633355.1"
                     /translation="MTKINYQALREAAERAIPAMERLLMLPVDDDLISEQELKDSGVD
                     IDALNAFKILAGPETVLALLDERERNQQYIKSRDQENEDIALTVGKLLIENGQLVADT
                     LRHLADNEIDSDYFAITSTNENGTEIDHEMSITDYALQAAGTVDELVAALEAAKSKLN
                     EQREYYEGVIADGSKRIAELESGSQAQKLVEAIIVAIENEQERLFDEDYLMDSKECID
                     VIREEVKRWNDSRAAGIRIKGE"
     gene            2723..3478
                     /locus_tag="IRB70_003490"
     CDS             2723..3478
                     /locus_tag="IRB70_003490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015964734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633356.1"
                     /translation="MIHYHGGPITPDTCAMRAWKGRHAFISFAHSGQINLAAEYCQSF
                     ALDNGAFTAWKAAGKNKIDWSDYYEFVARWKNHPGFDFAIIPDVIDGGEEENDALLNE
                     WPHGKLVGVPVWHMNESDERFIHLCNEFPRVAIGSCGDYDVKRPTLAVARMKDLIRHI
                     VDEHGQPVTKLHGLRMLNPLIFTKLPLASADSTNVARNIGIDKAWSGAYAPASKETRA
                     ALMVERIEAHNSPGSLAYCEQRDRFEMQLQLAV"
     gene            3489..4277
                     /locus_tag="IRB70_003491"
     CDS             3489..4277
                     /locus_tag="IRB70_003491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF551 domain-containing protein"
                     /protein_id="HBC0633357.1"
                     /translation="MTTITKERIELFIKNPLENGLTRGEQMELARIALASLEAEPVAW
                     MRDDADGREYNARNEFSGGGGGVPLYATPPVPVVPEEKPMPNPLSMYAVDAVAAIAEV
                     RGWNACRAAMLHGAEPASNHEELPLDYLQGQKDGLEWAAQLAEANHPQTGDWLYDDPL
                     ELAKAIRKGPDMPEFDGPTPVTPDGWISCSERMPEMGERQCYVLAADFKNNYSPNIPN
                     TQVGVYGDWFNDGNPTWDDGDGEDLYLKEVTHWMQLPEPPKEAK"
     gene            4274..4534
                     /locus_tag="IRB70_003492"
     CDS             4274..4534
                     /locus_tag="IRB70_003492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001554875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="eaa protein"
                     /protein_id="HBC0633358.1"
                     /translation="MMNVKEKVLQVMRSRAALQDKALGGEYPFRMATWNLRLAMEKEF
                     PDEEWSSADLRKILMEMAKDGTVSKDTHASRIGQAVWRLEVR"
     gene            4642..4986
                     /locus_tag="IRB70_003493"
     CDS             4642..4986
                     /locus_tag="IRB70_003493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633359.1"
                     /translation="MSDLAMKVLKWQSTGDVGISSATLASIACGLKKNIYGHHFDAPH
                     DAADFRRCVALVEQIPEIRDSFDKVAKRVPAFKGILNEWDSLVALLKSEMKTYGNKAP
                     ETYRRISELRKD"
     gene            5109..5309
                     /gene="torI"
                     /locus_tag="IRB70_003494"
     CDS             5109..5309
                     /gene="torI"
                     /locus_tag="IRB70_003494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator inhibitor TorI"
                     /protein_id="HBC0633360.1"
                     /translation="MQHELQPDSLVDLKFIMADTGFGKTFIYDRIKSGDLPKAKVIHG
                     RARWLYRDHCEFKNKLLSRANG"
     gene            complement(5497..6432)
                     /gene="dsdC"
                     /locus_tag="IRB70_003495"
     CDS             complement(5497..6432)
                     /gene="dsdC"
                     /locus_tag="IRB70_003495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator DsdC"
                     /protein_id="HBC0633361.1"
                     /translation="MEPLREIRNRLLNGWQLSKLHTFEVAARHQSFALAAEELSLSPS
                     AVSHRINHLEEELGIQLFVRSHRKVELTHEGKRVYWALKSSLDTLNQEILDIKNQELS
                     GTLTLYSRPSIAQCWLVPALGDFTRRYPSISLTVLTGNDNVNLQRAGIDLAIYFDDAP
                     SAQLAHHFLMDEEILPVCSPEYAQRHALTNQVINLRHCSLLHDRQAWSNDSGTDEWHS
                     WAQHYAVNLPTSSGIGFDRSDLAVIAAMNHIGVAMGRKRLVQKRLASGELVAPFGDMT
                     VKCHQHYYITTLPGRQWPKIEAFITWLREQVKTTS"
     gene            6650..7987
                     /gene="dsdX"
                     /locus_tag="IRB70_003496"
     CDS             6650..7987
                     /gene="dsdX"
                     /locus_tag="IRB70_003496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine transporter DsdX"
                     /protein_id="HBC0633362.1"
                     /translation="MHSQIWVVSTLLISIVLIVLTIVKFKFHPFLALLLASFFVGTMM
                     GMGPLDMVNAIESGIGGTLGFLAAVIGLGTILGKMMEVSGAAERIGLTLQRCRWLSAD
                     VIMVLVGLICGITLFVEVGVVLLIPLAFSIAKKTNTSLLKLAIPLCTALMAVHCVVPP
                     HPAALYVANKLGADIGSVIVYGLLVGLMASLIGGPLFLKFLGQRLPFKPVPTEFADLK
                     VRDEKTLPSLGATLFTILLPIALMLVKTIAELNMARESGLYTLLEFIGNPITAMFIAV
                     FVAYYVLGIRQHMSMGTMLTHTENGFGSIANILLIIGAGGAFNAILKSSSLADTLAVI
                     LSNMHMHPILLAWLVALILHAAVGSATVAMMGATAIVAPMLPLYPDISPEIIAIAIGS
                     GAIGCTIVTDSLFWLVKQYCGATLNETFKYYTTATFIASVIALAGTFLLSFII"
     gene            8005..9336
                     /gene="dsdA"
                     /locus_tag="IRB70_003497"
     CDS             8005..9336
                     /gene="dsdA"
                     /locus_tag="IRB70_003497"
                     /EC_number="4.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-serine ammonia-lyase"
                     /protein_id="HBC0633363.1"
                     /translation="MENAKMNSLIAQYPLVKDLVALKETTWFNPGTTSLAEGLPYVGL
                     TEQDVQDAHARLSRFAPYLAKAFPETAATGGIIESELVAIPAMQKRLEKEYQQPISGQ
                     LLLKKDSHLPISGSIKARGGIYEVLAHAEKLALEAGLLTLEDDYSKLLSPEFKQFFSQ
                     YSIAVGSTGNLGLSIGIMSARIGFKVTVHMSADARAWKKAKLRSHGVTVVEYEQDYGV
                     AVEEGRKAAQSDPNCFFIDDENSRTLFLGYSVAGQRLKAQFAQQGRIVDADNPLFVYL
                     PCGVGGGPGGVAFGLKLAFGDHVHCFFAEPTHSPCMLLGVHTGLHDQISVQDIGIDNL
                     TAADGLAVGRASGFVGRAMERLLDGFYTLSDQTMYDMLGWLAQEEGIRLEPSALAGMA
                     GPQRVCASVSYQQMHGFSAEQLRNATHLVWATGGGMVPEEEMEQYLAKGRS"
     gene            complement(9441..10979)
                     /gene="emrY"
                     /locus_tag="IRB70_003498"
     CDS             complement(9441..10979)
                     /gene="emrY"
                     /locus_tag="IRB70_003498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter permease
                     subunit EmrY"
                     /protein_id="HBC0633364.1"
                     /translation="MAITKSTPAPLTGGTLWCVTIALSLATFMQMLDSTISNVAIPTI
                     SGFLGASTDEGTWVITSFGVANAIAIPVTGRLAQRIGELRLFLLSVTFFSLSSLMCSL
                     STNLDVLIFFRVVQGLMAGPLIPLSQSLLLRNYPPEKRTFALALWSMTVIIAPICGPI
                     LGGYICDNFSWGWIFLINVPMGIIVLTLCLTLLKGRETETSPVKMNLPGLTLLVLGVG
                     GLQIMLDKGRDLDWFNSSTIIILTVVSVISLISLVIWESTSENPILDLSLFKSRNFTI
                     GIVSITCAYLFYSGAIVLMPQLLQETMGYNAIWAGLAYAPIGIMPLLISPLIGRYGNK
                     IDMRLLVTFSFLMYAVCYYWRSVTFMPTIDFTGIILPQFFQGFAVACFFLPLTTISFS
                     GLPDNKFANASSMSNFFRTLSGSVGTSLTMTLWGRRESLHHSQLTATIDQFNPVFNSS
                     SQIMDKYYGSLSGVLNEINNEITQQSLSISANEIFRMAAIAFILLTVLVWFAKPPFTA
                     KGVG"
     gene            complement(10979..12142)
                     /gene="emrK"
                     /locus_tag="IRB70_003499"
     CDS             complement(10979..12142)
                     /gene="emrK"
                     /locus_tag="IRB70_003499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter periplasmic
                     adaptor subunit EmrK"
                     /protein_id="HBC0633365.1"
                     /translation="MEQINSNKKHSDRKKYFALLAVVLFIAFSGAYAYWSMELEDMIS
                     TDDAYVTGNADPISAQVSGSVTVVNHKDTNYVRQGDILVSLDKTDATIALNKAKNNLA
                     NIVRQTNKLYLQDKQYSAEVASARIQYQQSLEDYNRRVPLAKQGVISKETLEHTKDTL
                     ISSKAALNAAIQAYKANKALVMNTPLNRQPQVVEAADATKEAWLALKRTDIKSPVTGY
                     IAQRSVQVGETVSPGQSLMAVVPARQMWVNANFKETQLTDVRIGQSVNIISDLYGENV
                     VFHGRVTGINMGTGNAFSLLPAQNATGNWIKIVQRVPVEVSLDPKELMEHPLRIGLSM
                     TATIDTRNEDIADMPDLASTVTSMPAYTSKALIIDTSPIEKEISNIISHNGQL"
     gene            12557..13171
                     /gene="evgA"
                     /locus_tag="IRB70_003500"
     CDS             12557..13171
                     /gene="evgA"
                     /locus_tag="IRB70_003500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system DNA-binding response
                     regulator EvgA"
                     /protein_id="HBC0633366.1"
                     /translation="MNAIIIDDHPLAIAAIRNLLIKNDIEILAELTEGGSAVQRVETL
                     KPDIVIIDVDIPGVNGIQVLETLRKRQYSGIIIIVSAKNDHFYGKHCADAGANGFVSK
                     KEGMNNIIAAIEAAKNGYCYFPFSLNRFVGSLTSDQQKLDSLSKQEISVMRYILDGKD
                     NNDIAEKMFISNKTVSTYKSRLMEKLECKSLMDLYTFAQRNKIG"
     gene            13176..16769
                     /gene="evgS"
                     /locus_tag="IRB70_003501"
     CDS             13176..16769
                     /gene="evgS"
                     /locus_tag="IRB70_003501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-sensing system histidine kinase EvgS"
                     /protein_id="HBC0633367.1"
                     /translation="MKFLPYIFLLCCGLWSTISFADGDYIEYRGISSNNRVTLDPLRQ
                     SNKELRWLASKKNLVIAVHKSQTATLLHTDSQQRIRGINADYLNLLKRALNIKLTLRE
                     YADHQKAMDALEDGEVDIVLSHLVASPPLNDDIAATNPLIITFPALVTTLHDSMRPLT
                     SSKPVNIARVANYPPDEVIHQSFPKATIISFTNLYQALASVSAGQNDYFIGSNIITSS
                     MISRYFTHSLNVVKYYNSPRQYNFLLTRKDSIVLNEVLNRFVDALTNEVRYEVSQNWL
                     DTGNLAFLNKPLELTEHEKQWIKQHPDLKVLENPYSPPYSMTDETGSVRGVMGDILNI
                     ITLQTGLNFSPITVSHNIHAGTQLNPGGWDILPAAIYSEDRENNVSFAEAFITTPYVF
                     VMQKAPDSEQTLKKGMKVAIPYYYELHSQLKEMYPEVEWIKVDNASAAFHKVKEGELD
                     ALVATQLNSRYMIDHYYPNELYHFLIPGVQNASLSFAFPRGEPELKDIINKALNAIPP
                     SEVLRLTEKWIKMPNVTIDTWDLYSEQFYIVTTLSVLLVGSSLLWGFYLLRSVRRRKV
                     IQGDLENQISFRKALSDSLPNPTYVVNWQGNVISHNSAFEHYFTADYYKNAMLPLENS
                     DSPFKDVFSNAHEVTAETKENRTIYTQVFEIDNGIEKRCINHWHTLCNLPASEHAVYI
                     CGWQDITETRDLIHALEVERNKAINATVAKSQFLATMSHEIRTPISSIMGFLELLSGS
                     GLSKEQRVEAISLAYATGQSLLGLIGEILDVDKIESGNYQLQPQWVDIPTLVQNTCHS
                     FGAIAASKSIALSCSSTFPERYLVKIDPQAFKQVLSNLLSNALKFTTEGAVKITTSLG
                     HIDDNHAVIKMTIMDSGSGLSQEEQQQLFKRYSQTSAGRQQTGSGLGLMICKELIKNM
                     QGDLSLESHPGIGTIFTITIPVEITQQVAAIETKAEQPITLPEKLSILIADDHPTNRL
                     LLKRQLNLLGYDVDEATDGVQALHKISMQHYDLLITDVNMPNMDGFELTRKLREQNSS
                     LPIWGLTANAQANEREKGLNCGMNLCLFKPLTLDVLKTHLSQLHQVAHIAPQYRHLDI
                     EALKNNTANDLQLMQEILMTFQHETHKDLPAAFHALEAGDNRTFHQCIHRIHGAANIL
                     NLQKLINISHQLEITPVSDDSKPEILQLLNSVKEHIAELDQEITAFCQQND"
     gene            complement(16825..17970)
                     /gene="yfdE"
                     /locus_tag="IRB70_003502"
     CDS             complement(16825..17970)
                     /gene="yfdE"
                     /locus_tag="IRB70_003502"
                     /EC_number="2.8.3.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416872.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA:oxalate CoA-transferase"
                     /protein_id="HBC0633368.1"
                     /translation="MTNNESKGPFEGLLVIDMTHVLNGPFGTQLLCNMGARVIKVEPP
                     GHGDDTRTFGPYVDGQSLYYSFINHGKESVVLDLKNDHDKSIFINMLKQADVLAENFR
                     PGTMEKLGFSWERLQEINPRLIYASSSGFGHTGPLKDAPAYDTIIQAMSGIMMETGYP
                     DAPPVRVGTSLADLCGGVYLFSGIVSALYGREKSQRGAHVDIAMFDATLSFLEHGLMA
                     YIATGKSPQRLGNRHPYMAPFDVFDTQDKPITICCGNDKLFSALCQALDLTELVDDPR
                     FISNILRVQNQAILKQYIERTLKTQAAEVWLARIHEVGVPVAPLLSVAEAINLPQTQA
                     RNMLIEAGGIMMPGNPIKISGCADPHVMPGAATLDQHGEQIRQEFSS"
     gene            complement(18044..18988)
                     /gene="yfdV"
                     /locus_tag="IRB70_003503"
     CDS             complement(18044..18988)
                     /gene="yfdV"
                     /locus_tag="IRB70_003503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter YfdV"
                     /protein_id="HBC0633369.1"
                     /translation="MLTFFIGDLLPIIVIMLLGYFSGRRETFSEDQARAFNKLVLNYA
                     LPAALFVSITRANREMIFADTRLTLVSLVVIVGCFFFSWFGCYKFFKRTHAEAAVCAL
                     IAGSPTIGFLGFAVLDPIYGDSVSTGLVVAIISIIVNAITIPIGLYLLNPSSGADGKK
                     NSNLSALISAAKEPVVWAPVLATILVLVGVKIPAAWDPTFNLIAKANSGVAVFAAGLT
                     LAAHKFEFSAEIAYNTFLKLILMPLALLLVGMACHLNSEHLQMMVLAGALPPAFSGII
                     IASRFNVYTRTGTASLAVSVLGFVVTAPLWIYVSRLVS"
     gene            complement(19057..20751)
                     /gene="oxc"
                     /locus_tag="IRB70_003504"
     CDS             complement(19057..20751)
                     /gene="oxc"
                     /locus_tag="IRB70_003504"
                     /EC_number="4.1.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxalyl-CoA decarboxylase"
                     /protein_id="HBC0633370.1"
                     /translation="MSDQLQMTDGMHIIVEALKQNNIDTIYGVVGIPVTDMARHAQAE
                     GIRYIGFRHEQSAGYAAAASGFLTQKPGICLTVSAPGFLNGLTALANATVNGFPMIMI
                     SGSSDRAIVDLQQGDYEELDQMNAAKPYAKAAFRVNQPQDLGIALARAIRVSVSGRPG
                     GVYLDLPANVLAATMEKDEALTTIVKVENPSPALLPCPKSVTSAISLLAKAERPLIIL
                     GKGAAYSQSDEQLREFIESAQIPFLPMSMAKGILEDTHPLSAAAARSFALANADVVML
                     VGARLNWLLAHGKKGWAADTQFIQLDIEPQEIDSNRPIAVPVVGDIASSMQGMLAELK
                     QNTFTTPLVWRDILNIHKQQNAQKMHEKLSTDTQPLNYFNALSAVRDVLRENQDIYLV
                     NEGANTLDNARNIIDMYKPRRRLDCGTWGVMGIGMGYAIGASVTSGSPVVAIEGDSAF
                     GFSGMEIETICRYNLPVTIVIFNNGGIYRGDGVDLSGAGAPSPTDLLHHARYDKLMDA
                     FRGVGYNVTTTDELRHALTTGIQSRKPTIINVVIDPAAGTESGHITKLNPKQVAGN"
     gene            complement(20805..>22032)
                     /gene="frc"
                     /locus_tag="IRB70_003505"
     CDS             complement(20805..>22032)
                     /gene="frc"
                     /locus_tag="IRB70_003505"
                     /EC_number="2.8.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="formyl-CoA transferase"
                     /protein_id="HBC0633371.1"
                     /translation="KVLDFTGVQSGPSCTQMLAWFGADVIKIERPGVGDVTRHQLRDI
                     PDIDALYFTMLNSNKRSIELNTKTAEGKEVMEKLIREADILVENFHPGAIDHMGFTWE
                     HIQEINPRLIFGSIKGFDECSPYVNVKAYENVAQAAGGAASTTGFWDGPPLVSAAALG
                     DSNTGMHLLIGLLAALLHREKTGRGQRVTMSMQDAVLNLCRVKLRDQQRLDKLGYLEE
                     YPQYPNGTFGDAVPRGGNAGGGGQPGWILKCKGWETDPNAYIYFTIQEQNWENTCKAI
                     GKPEWITDPAYSTAHARQPHIFDIFAEIEKYTVTIDKHEAVAYLTQFDIPCAPVLSMK
                     EISLDPSLRQSGSVVEVEQPLRGKYLTVGCPMKFSAFTPDIKAAPLLGEHTAAVLQEL
                     GYSDDEIAAMKQNHAI"
BASE COUNT         6360 a         4960 c         4932 g         5780 t
ORIGIN      
        1 tgaaagaatt aatcggtaac gaaggagata ttcatgtcac ttgcaaccac agtgaaggag
       61 agcaagttac agagacgcat gtacacgcag caggcgttaa tgtatcgcca gaagggagat
      121 cgtgaaggtg ttcgcgtatt tttaaatgcg gcaaagactg aagtattaaa tcagcgttat
      181 ttccttgggc catgtccatt ctgagaacaa tcatatgagc aaagaatttt acgcaagact
      241 ggcagctatt caggagaatc tgaacgcgcc aaagaatcag tacaactcat tcggaaaata
      301 taaatacaga agctgcgaag acattcttga aggcgttaag ccgttactga atggcctgtt
      361 tttatcaatc agcgatgaag ttgtgttgat tggtgatcgg tattatgtga aagccacggc
      421 aactattacc gatggcgaaa acagtcatac ggcaaccgca ctagcacgag aggaagaaag
      481 caagaaagga atggattctg cacaagttac gggagctaca agctcttatg cacgcaagta
      541 ttgcctcaat ggtttgttcg gcattgatga tgcgaaagat gcagataccg acgagcataa
      601 acatcagcag aacgcagcag caaagcaatc aaaaccatca cctacacctg aacaggttct
      661 aaaagcattc actgacgcag caatgcaaaa aaacaccgta gaagagctta aacaggcgtt
      721 cgccaaagcg tggaagatgc ttgaaggcac accggagcag cacaaagcgc aggacgttta
      781 caacatcaga cgagacgaat tagaaggagc ggctgcttaa tggcacattc gattactgta
      841 agactaaaca agcccgcaag agagtttcag accggggaaa atatcggatt caacatccgt
      901 gctggcgttc agtattacga tcgccagaca aaaaagaaag aatggacaaa ctacagcgcc
      961 gttgtatttg ccaagccggg agcgcaagcg gattactacc gtagtgttct tgttgaaggt
     1021 ggcattgtgg aaattaccgg agaaaacatc agggttgatg tttatcaggg gcaaaatggt
     1081 caatcaatca ctcttgaatt actgaatgca aagattggat ttgcagcttc aggaaatggc
     1141 ccgcagcagc aaagtagtaa ccagcagaac actcctgtat acgacgattc catcccattc
     1201 tgatttagaa aaataaggat ttaattatgc cagcgcctct gtatggtgcg gatgacccac
     1261 gccgctgttc cggcaattcc gtatcggagg tgctggataa attcaggaaa aactacgacc
     1321 ggataatgtc gctaccgcag gaaacgaaag aggaaaagga atttcgccat tgtatatggc
     1381 ttgcagagaa agaagaacgc gagcgaattt accagacatc aatccgacca ttccgcaaag
     1441 ccacatatac caacttccct gaatatatcg acccgcgcct gcgtaattac cgctcacgct
     1501 atggcgctat cagtaatgac tgaggaattt accatgagag gacttgcata caaccccggc
     1561 attcttccgg cagaaatgat tattcgccaa cgcgtaaagc caatgccatc gagagaggaa
     1621 ttgcttaaaa gaaattcttt tccttcagtg aatcaaaaca aatatctgaa tgcgatgtgg
     1681 cgtaaaggag gcaaccagtg actgtatgtc ttattgataa acgtcgacgt gggcaacaaa
     1741 taccatctgt tgaaatgccg aatcacacat ggttttgcgt acttgatatc gatggtatgg
     1801 atacgttgat cgacactcgt cattactgcg aaaccgcaac agctactcct gcaaaagcaa
     1861 agaaaatggc tgctctgata gaaaactgga ctccacctga tggttggtgc aatgggaatg
     1921 atcgagattg gcacgaaaaa atgaagggct atatctgcga ttttttacgt aaatgcaacg
     1981 gattcagggt gatgtgatat gaccaaaatt aactatcagg cactgcgtga ggcggcagag
     2041 cgtgcaattc cggcaatgga acgcctgtta atgttgccag ttgatgatga tctgataagc
     2101 gagcaggaac ttaaagatag cggtgttgat attgatgcgc tcaacgcctt caaaattctg
     2161 gccggaccag aaaccgtgct ggcgctactg gatgaacggg aaagaaacca gcaatacatc
     2221 aaatctcgcg accaggagaa cgaggatatt gcgctaacgg tagggaagct gttaatcgaa
     2281 aacggtcagc ttgttgccga tacgctacgc cacttagctg ataacgaaat cgactctgat
     2341 tattttgcta tcacctcaac taatgagaac ggtactgaaa ttgatcatga gatgtctatt
     2401 accgattacg cactgcaagc tgccggaact gtagacgaat tggttgcggc gctggaagcc
     2461 gcaaaatcaa aactcaacga gcagcgtgaa tattacgagg gagtaatcgc ggatggaagt
     2521 aagcgcatag cagagttaga aagtggttct caggcacaaa agttagttga agcaatcatt
     2581 gttgcgatag aaaacgaaca ggaaaggctt tttgatgaag attacctaat ggattcgaaa
     2641 gaatgcattg acgtaattcg tgaagaagta aagcgatgga atgattcccg tgccgctggc
     2701 attcgcatca aaggagagtg agatgattca ctatcacggt gggcctatta ctcctgatac
     2761 gtgcgcaatg agagcatgga aagggcgaca tgcgtttatc agttttgcgc attcaggcca
     2821 gatcaatctc gcggctgaat actgtcagtc gttcgcgctg gacaacggtg cattcaccgc
     2881 ctggaaagca gctggcaaaa acaaaatcga ctggagcgat tactacgagt ttgttgctcg
     2941 ctggaagaat cacccagggt tcgattttgc cattatcccg gatgttattg atggcggaga
     3001 ggaggaaaat gatgcgcttc tgaatgagtg gcctcacgga aaactagttg gcgttccagt
     3061 gtggcacatg aatgaaagtg acgagcgatt tattcatttg tgcaatgagt ttccgcgagt
     3121 ggctatcggt agttgtggcg actatgacgt aaagcgccca actcttgcgg tagccagaat
     3181 gaaagacctg attcgtcaca ttgttgatga gcatggtcag ccggttacga aactacatgg
     3241 attgcgcatg ttaaatccgc tgatattcac aaaattaccc ttagccagcg cagatagtac
     3301 gaacgtcgct cgaaacatcg gtattgataa agcctggtct ggggcttatg cacctgcaag
     3361 taaagagaca cgcgcagcat taatggtaga acggattgag gcacacaata gccctggttc
     3421 tcttgcgtat tgtgaacaac gcgaccgctt tgaaatgcaa ttgcaactgg cagtttaagg
     3481 actaacacat gaccactatt accaaagaac gtattgaatt gttcattaaa aatccgcttg
     3541 aaaacgggct tactcgtggc gaacaaatgg aactggcacg aattgcactt gcatcgctgg
     3601 aagcagaacc ggtggcgtgg atgcgtgatg acgcagatgg tcgtgagtat aacgctcgca
     3661 atgaattttc tggtggaggg ggaggagttc cactctacgc cacccctcca gtgccagtag
     3721 taccggaaga aaaaccaatg cctaatcctc ttagcatgta cgcggttgat gctgttgccg
     3781 ctattgcaga ggtgagaggc tggaacgcct gccgcgccgc catgcttcat ggtgccgaac
     3841 ctgcaagtaa tcatgaagag ttgccacttg attatctcca aggtcaaaaa gatggtcttg
     3901 aatgggctgc gcagcttgca gaagcaaatc acccacaaac tggcgactgg ctttacgatg
     3961 acccgctgga gctggctaaa gctatcagaa aaggtcctga catgcccgaa ttcgatggac
     4021 caactccggt aactccggat ggttggataa gctgtagtga gcgaatgcca gaaatgggag
     4081 agcgacaatg ctatgtgtta gcagctgact ttaaaaacaa ctactcacca aacatcccca
     4141 acactcaggt cggcgtatat ggcgactggt ttaatgatgg caatcccact tgggatgacg
     4201 gtgatggcga agacctgtat ctcaaagagg taacccactg gatgcagcta ccagaacctc
     4261 cgaaggaggc gaaatgatga atgtaaaaga gaaggttttg caggtgatgc gttcccgggc
     4321 tgccctgcaa gataaagctc tcggcgggga atatccattc aggatggcaa cctggaatct
     4381 gcggttggca atggagaagg aatttcctga tgaagaatgg agttcggcag atttgcgcaa
     4441 aattcttatg gagatggcta aagatggaac agtatccaaa gatacccatg ccagccggat
     4501 tggtcaggcg gtatggagac tggaggtgcg gtaatggcta acctgcaact tgccgtcaaa
     4561 ggtgaataac aatcctcgaa ctcgcgggga tttcttttat ctgagctcgc tacggcgagt
     4621 tttgttttat ggagacaaga aatgtcagat ttggctatga aggttttgaa atggcaatcg
     4681 actggcgatg ttggcatcag tagcgcaact cttgcctcaa tcgcatgtgg actgaaaaag
     4741 aatatctatg gtcatcactt cgacgctccc catgacgcag cagactttcg gcgatgcgtt
     4801 gcacttgttg agcagattcc agaaatcaga gattcattcg acaaggttgc aaagcgcgtt
     4861 ccggcattca aaggaatcct caacgaatgg gattcactcg ttgctctgtt gaagtctgaa
     4921 atgaagacgt acgggaacaa agcaccagag acttacagaa gaatcagcga gctacgcaag
     4981 gactaacccg cctcacactc gatgaggcat tttcatttat caagatatcc agacctacca
     5041 tcgccgcatc aatgcggttt tttattgcct gatttgcagg ttcgattccc tattcggaga
     5101 tagcactcat gcaacacgaa ctacagcctg attcactggt tgatttgaaa ttcatcatgg
     5161 ccgatactgg cttcggtaaa accttcatct acgaccggat taagtccggc gacctgccaa
     5221 aagccaaagt tatccacgga cgagcaagat ggttatatcg tgaccattgt gaattcaaaa
     5281 ataagctctt aagccgcgcc aatgggtaaa atagcgggta aaatattttt cacatctaaa
     5341 aaacatcatt ccaatcaatc ccctgccgcg ccaagtagat gtctgcaggg gacaccatcc
     5401 ttgtgtttat ccctaaaacc acataaaaac cgtaaattat taaattcgca ctagcagtgc
     5461 cgaataaggc acaccaggaa ctcgtggtct tattcattat gaagtggttt ttacctgttc
     5521 tcttaaccaa gtaataaatg cctcaatttt tggccactgc ctgcccggta atgtggtgat
     5581 gtaataatgc tgatggcatt tcaccgtcat atcgccaaac ggcgcgacga gctcaccact
     5641 ggcaagcctt ttttgtacca ggcgttttct tcccatcgct accccaatat gattcatcgc
     5701 agcgataaca gctaaatcag aacgatcaaa gccaatccca gaagatgtcg gcaaattaac
     5761 cgcataatgt tgcgcccaac tatgccattc atccgtaccg gagtcgttgc tccatgcctg
     5821 tctgtcatgg agcaacgaac agtggcgcag gttaattacc tggttggtta aagcatgtct
     5881 ttgagcgtat tccgggctac atacaggcaa gatttcttca tccatcagaa agtgatgagc
     5941 caattgcgct gacggcgcat catcaaagta gatcgccaaa tcgattccgg cacgttgcaa
     6001 attgacattg tcattaccag tgagcacggt gagcgaaata gacggatatc ggcgtgtaaa
     6061 gtcacctaat gcgggcacca accagcattg ggcgatagag ggccgggaat acagcgttaa
     6121 cgttcccgat aattcctgat ttttgatatc aagaatttcc tggttcaggg tatccagcga
     6181 cgattttagc gcccaataaa cgcgtttccc ctcgtgcgtt aattccactt tgcgatggga
     6241 acgaacaaac aactgaatac ctaattcttc ttccagatga ttgatacggt gacttaccgc
     6301 actggggctc agcgacaatt cctctgccgc aagggcgaag gactgatgcc tggcagccac
     6361 ttcaaaagta tgcagttttg atagttgcca gccgttaagc agtcgatttc ttatttcacg
     6421 aaggggttcc ataatcacct catttttctc ttaagtgtaa aaaaatagcg gcaaaatttc
     6481 agctgcaagg tgaactaaag tgaaccatat ctcaattcac cttcattttt agatgtaaat
     6541 cactcccttg atgcaattta gctcacgtga aaggcaaatt ttatcgtttg tcagcctgcg
     6601 ttgttttttt gtccaatatc atcaggttaa tcacagggga aggtgagata tgcactctca
     6661 aatctgggtt gtgagcacgc tgcttatcag catcgtgtta attgtactga ccatcgtgaa
     6721 gttcaaattc cacccgtttc tggcgctgtt gctggccagc ttcttcgtgg gaacgatgat
     6781 gggtatggga ccactggata tggtaaatgc tattgaaagt ggaattggcg gaacgctggg
     6841 gttccttgct gcggttatcg gcctgggcac gatactggga aaaatgatgg aagtatccgg
     6901 ggccgcagaa agaattggtc tgacacttca acgctgtcgc tggctttcag ctgatgtcat
     6961 tatggtgctg gttggcctga tttgcggcat cacgctgttt gttgaagtgg gcgtcgtgct
     7021 attgattcct ctggcttttt caattgcaaa aaaaaccaat acctcattgt taaagctggc
     7081 cattccgctg tgtaccgcat tgatggcagt gcactgcgtg gttcccccac atccggctgc
     7141 tttatatgtt gccaataagc ttggcgcaga tatcggttcg gtgatcgtct acggtttgct
     7201 ggttgggctg atggcatcac tgatcggtgg cccacttttc cttaaatttc tgggtcaacg
     7261 actgcccttt aaacctgtac ccacagagtt tgccgatctc aaagttcgcg atgaaaaaac
     7321 actaccgtca ttaggcgcaa cgttattcac catactgcta cccattgcgc tgatgttggt
     7381 taaaacgatt gccgaattga atatggcgcg tgagagtggt ttgtatacct tgcttgagtt
     7441 tattggcaac cctattactg ccatgtttat cgccgtgttt gtcgcctatt atgtgttggg
     7501 tatacgccag catatgagca tggggacgat gctcacacat acggaaaatg gcttcggttc
     7561 tattgctaat attttgctga ttatcggggc cggaggcgca ttcaacgcca ttttaaaaag
     7621 cagcagtctc gctgatacgc tggcagttat tctctccaat atgcatatgc acccgattct
     7681 tctggcctgg ttggtggcac ttattctgca tgctgcagtg ggctccgcta cggtggcaat
     7741 gatgggggca acggcaattg ttgcacccat gctgccgctg tatcccgaca tcagcccgga
     7801 aattattgcg attgctatcg gttcaggtgc gattggctgc acgatcgtta cggactcgct
     7861 tttctggctg gtgaagcaat attgcggcgc tacgctcaat gaaacattta aatactatac
     7921 gacagcgaca tttatcgctt cagtcatcgc tctggcgggc acattcctgc tgtcatttat
     7981 catctaagcg caaagagacg tactatggaa aacgctaaaa tgaactcgct catcgcccag
     8041 tatccgttgg tcaaggatct ggttgctctt aaagaaacca cctggtttaa tcctggcacg
     8101 acctcattgg ctgaaggttt accttatgtt ggcctgaccg aacaggatgt tcaggacgcc
     8161 catgcgcgcc tgtctcgttt tgcaccctat ctggcaaaag catttcctga aactgctgct
     8221 actgggggga ttattgaatc agaactggtt gccattccgg ctatgcaaaa acggctggaa
     8281 aaggaatatc aacaaccgat cagcgggcaa ctgctactga aaaaagatag ccatttgccc
     8341 atttccggct ccataaaagc acgcggcggg atttatgaag tcctggcaca tgcagaaaaa
     8401 ctggctctgg aagcggggtt gctgacgctt gaagatgact acagcaaact gctttccccg
     8461 gagtttaaac agttctttag tcaatacagc attgctgtgg gctcaaccgg aaatctgggg
     8521 ttatcaatcg gcattatgag cgcccgcatt ggctttaagg tgacagtgca tatgtctgct
     8581 gatgcccggg cgtggaaaaa agcgaaactg cgcagccatg gcgttacggt cgtggaatat
     8641 gagcaagatt atggtgttgc cgtcgaggaa ggacgtaaag cagcgcagtc tgacccgaac
     8701 tgtttcttta ttgatgacga gaattcccgc acgttgttcc ttgggtattc cgtcgctggc
     8761 cagcgtctta aagcgcaatt tgcccagcaa ggtcgtatcg tcgatgctga taaccctctg
     8821 tttgtctatc tgccgtgtgg tgttggtggt ggtcctggtg gcgtcgcatt cggacttaaa
     8881 ctggcgtttg gcgatcatgt tcactgcttt tttgccgaac caacgcactc cccttgtatg
     8941 ttgttaggcg tccatacagg attacacgat cagatttctg ttcaggatat tggtatcgac
     9001 aaccttaccg cagcggatgg ccttgcagtt ggtcgcgcat caggctttgt cgggcgggcg
     9061 atggagcgtc tgctggatgg cttttatacc cttagcgatc aaaccatgta tgacatgctt
     9121 ggctggctgg cgcaggaaga aggtattcgt cttgaaccat cggcactggc gggtatggcc
     9181 gggcctcagc gcgtgtgcgc atcagtaagt taccaacaga tgcacggttt cagcgcagaa
     9241 caactgcgta atgccactca tctggtgtgg gcgacgggag gtggaatggt gccggaagaa
     9301 gagatggagc aatatctggc aaaaggccgt tcataacgtt tcaacgcagc atcgccatcc
     9361 tttccctggg tgagcgatgc tgccgatggc gcagacttaa gatccccggt cttacccgct
     9421 ataacccctt gcttttacca tcacccaacg cctttcgctg taaacggcgg tttcgcaaac
     9481 caaaccaaaa ccgtaagtaa gataaaagca atagccgcca tacggaaaat ctcatttgca
     9541 gaaatagaaa gtgactgctg ggttatttca ttattaattt cattaagaac tcctgaaagc
     9601 gaaccatagt atttatccat aatttgtgac gatgaattaa acacggggtt aaattgatcg
     9661 atggttgctg tcaactgact atggtgtaac gattcgcggc gtccccacag tgtcattgtc
     9721 aacgacgtac caactgatcc tgacaaggtg cgaaaaaaat tactcatact cgaggcattg
     9781 gcaaatttat tatctggcaa gcctgaaaac gaaatcgttg ttaagggtaa aaagaaacag
     9841 gcaacggcga atccctggaa aaactgtggc aaaatgatgc ctgtaaaatc aatcgttggc
     9901 ataaatgtca cagaacgcca gtaatagcaa accgcataca tcaaaaaact aaatgtcacc
     9961 aacaaccgca tatctatttt gttgccataa cgccctatca aaggtgatat taatagcggc
    10021 atgataccga tgggcgcata ggcaagtccg gcccatatcg cattataccc catcgtttcc
    10081 tggagtaact gcggcataag gacgatcgct ccagagtaaa ataaatacgc gcatgtgata
    10141 ctcacaatac caatggtgaa attacgggac ttaaacaaac tgagatcaag aatcgggttc
    10201 tctgaggtcg actcccaaat gactaaagag atcagagaaa taactgatac tactgttaat
    10261 attattattg tactcgagtt gaaccaatcc agatcgcgcc ctttatcaag cataatttgc
    10321 aagccaccaa caccgagcac taacagggtc agtcctggta gattcatttt gaccggtgaa
    10381 gtctcagttt ctcgtccttt aagtaaggtt aagcataatg tcaggacgat aatccccata
    10441 gggacattga ttaaaaatat ccaaccccag ctaaagttat cacaaatata accgcccaat
    10501 atcggcccac atatcggcgc gataatcacg gtcatagacc ataatgccag agcaaatgtt
    10561 cttttttctg gtggataatt ccttaataat aaactctgtg acagtggaat taacggcccc
    10621 gccattaatc cctgaacgac tctaaaaaat atcagcacat caagattggt cgataaacta
    10681 cacattaagg aagacagcga aaaaaaagtg actgaaagta aaaataacct taattcgcct
    10741 attctttgtg ccagcctgcc ggtaacaggg atcgcaatgg catttgctac gccaaacgaa
    10801 gtgataaccc aggtgccttc gtctgttgat gctcccagaa agccagatat tgtcggtatt
    10861 gcgacgttag aaatagtgga atccaacatt tgcataaacg tcgctaatga caatgcaata
    10921 gtaacgcacc ataacgtccc accggttaat ggtgccggag ttgatttagt gattgccatt
    10981 aaagttgtcc attatgcgaa ataatgttgc taatttcttt ttctatcgga ctggtatcga
    11041 taattaaagc cttactggta taagcaggca tggacgtcac ggttgaagcc agatcgggca
    11101 tatcggcaat gtcttcgttc ctggtatcaa tagttgcagt catcgataaa ccaatgcgca
    11161 agggatgttc catgagttct tttggatcaa gagaaacctc aaccggtaca cgctgaacga
    11221 ttttgatcca attccctgtc gcattttgtg caggtaataa ggagaacgca ttgccggttc
    11281 ccatattgat ccctgtcacc cgaccatgaa acacaacatt ttcaccataa agatcgctaa
    11341 taatattgac cgattgacca atccgcacat ccgtgagttg tgtttcttta aagttggcat
    11401 taacccacat ttgacgtgcc ggtacgacag ccattaacga ttgtccggga ctcactgttt
    11461 cgccgacctg aacacttcgc tgggcaatat agccggtaac cggactctta atatccgtac
    11521 gtttaagcgc caaccaggct tctttggttg catccgccgc ttcaacgact tgtggctgac
    11581 ggtttaatgg tgtgttcatt actaaagctt tattcgcttt ataagcctga atagcagcat
    11641 tcaatgccgc tttgctactt attaacgtat ctttggtatg ctccagcgtt tcttttgaaa
    11701 taaccccctg cttcgctaaa ggtacacgac ggttataatc ttctaaagat tgttgatact
    11761 gaatacgagc tgaagcgact tcggcactgt attgtttatc ctgtaagtac agtttattcg
    11821 tttgccgaac aatattggcc agattatttt tagctttatt gagtgcgata gtggcatcag
    11881 tcttatccag tgagactaaa atgtcaccct gtcgaacgta gttcgtatct ttatgattaa
    11941 cgacagtgac gctgcctgaa acttgtgcag aaattggatc tgcatttccc gtgacatagg
    12001 cgtcatctgt actaatcatg tcttctaatt ccattgacca ataggcatag gcacctgaaa
    12061 acgcaataaa taaaactacc gctaacaaag caaaatattt ttttctgtca gaatgttttt
    12121 tatttgaatt aatctgttcc acttttatct ctcatttcgc atagatgaaa tttatgaatt
    12181 gaatgaaaag agaattcatt cttcatatca aacacagtgc atgtgttgca cattatccca
    12241 ggaacgttgg aggcctaatt taaatgaggt gcaaaaaaaa caacagagga ctaaaccgtg
    12301 gcttttgcaa tacaattctt acgcctgtag gattagtgag aagacttata gtgctaatgt
    12361 gaaactataa atcatcggta caatccctga ttttattgtt gacatttcat atatgccgac
    12421 tatttatatg gtatacttgt cgaattatct taaaggaagc tcaaattttc ttattttttt
    12481 gagaaaatga gatgatgcct tatgtctgta ttactacagg gagaagggaa atgcttcatt
    12541 gcaaagggaa taatctatga acgcaataat tattgatgac catcctcttg ctatcgcagc
    12601 aattcgtaat ttattgatca aaaacgatat tgaaatctta gcagagttga ctgaaggcgg
    12661 aagtgccgtt cagcgggtgg aaacacttaa gcctgatatc gtcatcattg atgtcgatat
    12721 ccccggagtt aacggtatcc aggtgttaga aacgctgagg aagcgccaat atagcggaat
    12781 tattattatc gtctccgcta aaaatgacca tttttacggg aaacattgtg ctgatgctgg
    12841 cgctaatggt ttcgtgagta aaaaagaagg catgaacaat atcattgcgg ctattgaagc
    12901 tgcaaaaaat ggctactgct atttcccttt ctctctcaac cggtttgttg gaagtttaac
    12961 gtccgaccag caaaaactcg actccttatc gaaacaagaa attagtgtca tgcggtatat
    13021 tcttgatggc aaggataata atgacattgc tgaaaaaatg ttcatcagca acaaaactgt
    13081 cagcacgtat aaaagtcgct tgatggaaaa attagaatgc aaatcactga tggatcttta
    13141 cacattcgca caacgtaaca aaatcggcta accacatgaa gtttttaccc tatatttttc
    13201 ttctctgttg tggtctttgg tcgaccataa gtttcgcaga cggagattac atcgaatatc
    13261 gtggcatcag tagtaacaac cgtgtcacac ttgatccact acgtcagagc aacaaggaat
    13321 tacgttggct cgcgagcaaa aaaaatcttg tgattgcagt acacaagtcc caaacagcta
    13381 cgttgttgca taccgattcg cagcaacgga ttcgtggtat taatgctgat tatttaaatc
    13441 ttttaaaaag agcgttaaat atcaaattaa cactccggga atacgcagat catcaaaaag
    13501 caatggacgc gctggaagac ggtgaagttg atatagtgtt atcacattta gttgcttcgc
    13561 cgcctcttaa tgatgacatt gctgcaacta atcctctgat aattaccttt cctgcgttgg
    13621 tcactaccct tcacgattca atgcgaccgc ttacctcatc aaaaccagta aatattgctc
    13681 gagtagcaaa ttatccccca gacgaggtaa ttcatcaatc atttccaaaa gcaacaatta
    13741 tctcttttac aaatttatat caggcattag catccgtctc agccggacag aatgattact
    13801 ttattggtag taacatcatt accagcagta tgatttcccg ttattttact cactccttaa
    13861 atgtagtgaa gtattataac tcaccgcgtc aatataactt tttattaacc agaaaagatt
    13921 caatcgttct taatgaagta ctcaatcgat ttgttgatgc tttaacaaat gaagttcgct
    13981 atgaagtatc acaaaattgg cttgatacag gaaacctggc ctttctgaac aaaccattag
    14041 aactcactga acatgaaaaa cagtggatta agcagcatcc cgatttaaag gtgctagaaa
    14101 atccttactc gccaccctat tctatgacag atgaaactgg ctcagttcgg ggcgtgatgg
    14161 gtgatattct taatattatt accttgcaaa caggtttaaa tttttctccg atcaccgttt
    14221 cacacaatat tcatgctggg acacagctta accccggtgg atgggatata ttgcccgccg
    14281 ctatttatag tgaagatcga gaaaataatg tttcatttgc tgaagctttc ataacaacgc
    14341 cttacgtttt tgtcatgcaa aaagcgcctg acagtgaaca aacattaaaa aaaggaatga
    14401 aagttgccat tccatattat tatgagcttc attcgcaatt aaaagagatg tatccggagg
    14461 tagagtggat aaaagtcgat aacgccagcg ctgcatttca caaggtcaag gaaggtgaac
    14521 ttgatgctct ggtcgcgaca cagttaaatt cgcgttacat gatcgaccat tactatccta
    14581 atgaacttta tcattttctt attcccggcg ttcagaatgc atcactttcg ttcgcttttc
    14641 ctcgcggaga accggaactt aaggatatta ttaataaagc actgaatgca attcccccaa
    14701 gcgaagttct gcgcctgacg gaaaaatgga ttaaaatgcc caatgtgacc attgacacat
    14761 gggacctcta tagcgagcaa ttttatattg tcacgacatt atccgtttta ttagttggca
    14821 gtagcctttt atggggattc tacctgttac gctcagttcg tcgtcgtaaa gtcattcagg
    14881 gtgatttaga aaaccaaata tcattccgaa aagcactctc ggattcctta ccgaatccaa
    14941 cttatgttgt aaactggcaa ggtaatgtca ttagtcataa tagtgctttt gaacattatt
    15001 tcactgcgga ttactacaaa aatgcaatgt taccattaga aaacagtgac tcacccttta
    15061 aagatgtttt ttctaatgcg catgaagtca cagcagaaac gaaagaaaat cgaacaatat
    15121 acacacaggt atttgaaatt gataatggca tcgagaaaag atgcattaat cactggcata
    15181 cattatgcaa tctgccagca agcgaacatg ctgtttatat ttgtggttgg caagatatta
    15241 ccgagacgcg tgatttaatt catgcactcg aagtagagag aaataaagcg atcaatgcaa
    15301 ctgtcgcaaa aagtcagttt ctggcaacaa tgagtcacga aataagaaca ccaataagct
    15361 ccattatggg cttcctggaa cttctgtcgg gttctggtct tagcaaggag caacgggtgg
    15421 aggcgatttc acttgcctac gccaccggac aatcactcct cggcttaatt ggtgaaatcc
    15481 ttgatgtcga caaaattgag tcgggtaact atcaacttca accacaatgg gtcgatatcc
    15541 ctactttagt ccagaacact tgtcactctt tcggtgcgat tgctgcaagc aaatccatcg
    15601 cattaagttg cagcagtacg tttcctgaac gctacctggt taagatcgac cctcaggcgt
    15661 ttaagcaggt cttatctaat ttactgagta atgctctcaa atttactacc gagggagcag
    15721 taaaaattac gacctccctg ggtcacattg atgacaacca cgctgttatc aaaatgacga
    15781 ttatggattc tggaagtgga ttatcgcagg aagaacaaca acaactgttt aaacgctata
    15841 gccaaacaag tgcaggtcgt cagcaaacag gttctggttt aggcttaatg atctgcaaag
    15901 aattaataaa aaacatgcag ggcgatttgt cattagaaag tcatccaggc ataggaacga
    15961 tatttacgat cacaatcccg gtagaaatta cccaacaagt ggcggctata gagacaaaag
    16021 cagaacaacc tatcacacta cctgaaaagt tgagcatatt aatcgcggat gatcatccga
    16081 ccaacaggct attactcaaa cgccagctaa atctattagg atatgatgtt gatgaagcca
    16141 ctgatggtgt gcaagcgcta cacaaaatca gtatgcaaca ttatgatctg cttattactg
    16201 acgtaaatat gccgaatatg gatggttttg agttgactcg caaactccgt gagcaaaatt
    16261 cttccttacc catctggggg cttacagcca acgcacaggc taacgaacgt gaaaaagggt
    16321 taaattgcgg catgaactta tgtttgttca aaccgttgac tctggatgta ctgaaaacac
    16381 atttaagtca gttacaccag gttgcgcata ttgcacctca gtatcgccac cttgatatcg
    16441 aggccctgaa aaataatacg gcgaacgatc tacaactgat gcaggagatt ctcatgactt
    16501 tccagcatga aacgcataaa gatctacccg ctgcgtttca tgcactagaa gctggcgata
    16561 acagaacttt ccatcagtgt attcatcgca tccacggtgc ggctaacatc ctgaatttgc
    16621 aaaagttgat taatattagc catcagttag aaataacacc tgtttcagat gacagtaagc
    16681 ctgaaattct tcagttgctg aactctgtaa aagaacacat tgcagagctg gaccaggaga
    16741 ttactgcttt ctgtcagcaa aatgactaaa tagcggctcc cacaatgttc aaatgtggga
    16801 gctatttacc agcacatctt acatttatga tgagaactcc tggcgaattt gttccccatg
    16861 ctggtcgagc gttgccgctc ccggcataac atgcgggtcc gcacagccgc taatttttat
    16921 cggattaccc ggcatcatta ttcccccggc ttcaatcaac atatttcttg cctgagtttg
    16981 tggtaaatta atggcctcag ccacacttaa taacggcgcg acaggcacac caacttcatg
    17041 tattctggct aaccaaactt cagctgcctg cgtttttaac gtccgctcaa tatattgttt
    17101 aagaatagcc tggttttgta cgcgtaaaat attgctgata aatcggggat catcaaccag
    17161 ctccgtcaga tccagtgcct gacataacgc agaaaaaagc ttgtcattac cacaacaaat
    17221 cgtaatcggc ttatcctgag tatcgaaaac atcaaaaggt gccatgtagg gatggcgatt
    17281 tcccagacgt tgtggtgact tcccagtcgc gatatatgcc atcagtccgt gctccagaaa
    17341 actcagagtg gcatcaaaca tcgctatatc gacatgcgca cctctctggc tcttttcgcg
    17401 gccataaagt gcactcacta ttccactgaa taaataaaca ccgccacata gatccgcaag
    17461 agaggtacca acgcgcactg gcggagcatc agggtatcct gtttccatca ttatcccgct
    17521 cattgcctga atgatggtat cgtaggcagg agcatctttt agcggaccgg tatgtccgaa
    17581 acctgacgat gaagcatata taaggcgcgg gttgatttct tgtaaccttt cccatgaaaa
    17641 cccgagtttt tccattgtac ctgggcgaaa attctcagct aatacatcag cttgtttaag
    17701 catatttata aatatacttt tatcgtgatc attctttaaa tcaagaacca cactctcttt
    17761 gccatgatta ataaaactgt aatagagtga ctgtccatcc acatagggac caaatgtgcg
    17821 ggtatcatca ccatggcccg gcggctcaac tttaattacc cttgcgccca tattacaaag
    17881 aagttgagtt ccgaaaggtc cattaaggac atgtgtcata tcgataacta ataagccttc
    17941 aaacggccct ttgctttcat tatttgtcat ttgcttatgc cttgaaaaaa gccgaaggtg
    18001 aaaagacact tcggcattta tgtaaaatca ataacatgat taattatgaa accagtcgac
    18061 tgacataaat ccacaaggga gccgtgacga caaaacccag tacgctcaca gccaatgacg
    18121 ctgtaccagt gcgggtgtag acattaaacc gactggcaat aatgattccg gagaatgccg
    18181 gcggtaatgc gcctgccagt accatcatct gcaaatgttc gctgttcaaa tgacatgcca
    18241 tacccacgag aagcagcgcc agtggcatca gaatcagctt caggaaggtg ttataagcaa
    18301 tttcggcact gaactcgaat ttatgtgcag ccagagtcaa ccccgcagcg aacaccgcta
    18361 cccctgagtt agccttcgca atcagattaa aggttgggtc ccatgctgcc ggaattttta
    18421 ccccaaccaa caccaggatc gttgccagaa caggtgccca tactactggc tcctttgccg
    18481 cagaaattaa tgcgctcaga ttactattct tcttaccatc cgctcctgag gaaggattca
    18541 gcaaatacag accaatagga atagtaattg cgttaacaat aatagaaata attgctacca
    18601 ctaaacctgt tgatacggaa tcaccataaa taggatcgag aactgcaaac cccaggaatc
    18661 cgatggtagg tgagcctgca attaatgcac atactgctgc ttctgcatgg gtacgtttaa
    18721 aaaatttgta gcaaccaaac caggagaaaa agaaacatcc gacaataacc acaagtgata
    18781 caagggtcag gcgagtgtcc gcaaaaatca tttccctgtt tgcccgggta atagaaacaa
    18841 atagggccgc aggaagagcg tagtttaata ccagtttatt aaatgcccgg gcttgatctt
    18901 ctgaaaaagt ttctcgtctg ccgctaaaat aacccaacag catgattacg ataataggca
    18961 ataaatcgcc aataaaaaat gttagcataa tagtatttcc gataagggtc ccctcaccat
    19021 cgataatgag ttggcaagag gagacgatgt cagtatttaa ttaccagcga cttgttttgg
    19081 gttaagtttg gtaatatggc cactttcagt tcctgctgca gggtcgatga ccacattaat
    19141 aatggtcggt ttgcgcgact gaataccggt ggttaaagca tgacgaagtt catctgtcgt
    19201 ggtgacgtta tagccaacgc cacgaaacgc atccattaat ttgtcatacc ttgcatggtg
    19261 caacagatct gttggtgatg gtgcaccagc gccactgaga tcaacaccgt ctcctctgta
    19321 gatgccgcca ttattaaaaa taacgatcgt caccggcagg ttatatcgac aaatcgtttc
    19381 aatctccatc ccactgaaac caaaagcact atcaccttca atggcgacaa ccggagaacc
    19441 agaggtcacg ctagcaccga tggcatagcc cataccgatg cccatgacac cccaggtgcc
    19501 acaatccaga cgacgacgtg gtttatacat atcaataata tttcgtgcat tatccagggt
    19561 atttgcacct tcattaacta aataaatatc ctggttctcg cgcaatacat cgcgcacagc
    19621 acttaatgca ttaaagtaat ttaatggttg agtatctgta cttaattttt catgcatttt
    19681 ttgcgcattt tgctgcttgt ggatatttaa aatatcgcgc cataccagtg gagtcgtaaa
    19741 tgtgttttgt ttcagttctg ccagcatacc ttgcatactg gatgcaatat cgccaacgac
    19801 tggcacagca atggggcggt tgctgtcaat ttcctgcggt tcaatatcca gttgaataaa
    19861 ctgtgtatct gccgcccatc cttttttacc gtgtgccagt aaccaattca gtcgtgcgcc
    19921 aacaagcatg acaacgtcag catttgccag ggcaaacgaa cgcgcagctg ccgcagaaag
    19981 tggatgcgta tcttcgagga tccctttcgc catagacatt ggcaggaatg gaatctgggc
    20041 actttcaata aattcacgaa gctgttcatc agattgtgaa tacgccgcgc ctttgccaag
    20101 gataattaat ggtcgttcag cttttgctaa aagcgaaatt gcgctagtga ctgacttcgg
    20161 gcatggcaat aatgctggcg acggattttc aactttaaca atcgtggtta acgcttcgtc
    20221 tttttccatc gtcgcggcca ggacatttgc tggcaaatca agataaacac cgccaggacg
    20281 acccgatact gagacccgga tagcacgtgc caatgcaatg ccaagatcct gcggctgatt
    20341 aacgcgaaat gctgctttgg catacggttt tgccgcattc atttggtcca gctcttcata
    20401 atcaccttgc tgtaggtcga cgatcgcgcg gtcgctggag ccgctaatca tgatcatcgg
    20461 aaaaccattt accgttgcat tggccaatgc ggtcaaaccg ttgaggaatc ctggcgcaga
    20521 cactgtcagg cagatccctg gtttttgggt aagaaaaccg cttgctgcag cggcatagcc
    20581 tgccgactgc tcatgacgaa aaccaatata acgaatgcct tccgcctggg catggcgcgc
    20641 catatccgtc acaggaatac ctacaacacc ataaatagtg tcaatattat tctgttttaa
    20701 tgcttcaacg atgatatgca taccatctgt catttgaagt tgatctgaca tgattaataa
    20761 cctcgaaatt tttataaatt gggagccaga agcccccgtt aatatcagat ggcgtggttt
    20821 tgcttcattg cagcaatttc atcgtcgcta taacccagct cctgcaatac agcagcggta
    20881 tgttcaccta atagcggcgc agctttaata tccggcgtaa aggcagagaa tttcattgga
    20941 caaccaactg tcagatattt tccacgcaac ggttgttcca cttcgacaac actgccactt
    21001 tggcgcaaag agggatcaag tgaaatttct ttcatactta aaaccggtgc acaaggaata
    21061 tcaaactgag tcaaataggc cacagcttca tgtttatcaa tagtgacagt gtatttttcg
    21121 atttcagcaa aaatatcgaa aatatgtggc tgtcgggcat gggctgtact gtatgccgga
    21181 tcggtaatcc attctggttt gccgatggct ttacaggtgt tttcccagtt ttgctcctga
    21241 atagtgaaat aaatataggc attaggatcg gtttcccagc ctttacattt caggatccag
    21301 ccaggctgac caccaccccc cgcattacca ccgcggggaa ctgcatcacc aaatgtgcca
    21361 ttcggatact gcgggtattc ttccagataa cccaatttat cgagacgctg ctggtcgcgt
    21421 aatttcacgc ggcaaaggtt caacacggca tcctgcattg acatggtcac tcgttgccca
    21481 cgccccgttt tttcgcgatg cagcaaagca gcaagtaaac cgatcagtaa atgcattccg
    21541 gtgttgctgt cacccaacgc tgcagcgctt accagcggcg gaccgtccca aaaacccgta
    21601 gtagatgccg cgccacccgc tgcctgagca acgttttcat aggcttttac attcacataa
    21661 ggcgaacact catcaaaccc tttgatcgaa ccaaaaatca gacgtggatt gatttcttga
    21721 atatgctccc aggtgaagcc catatgatca atggccccag gatgaaagtt ctcgactaag
    21781 atatcagctt cgcggatcag cttttccatt acctctttgc cttccgctgt tttggtattt
    21841 aattcaatag aacgtttgtt actgttaagc atggtgaagt aaagcgcatc gatatcagga
    21901 atatctcgca gctggtgacg cgttacgtca ccaacaccgg gacgttcaat tttaatgacg
    21961 tcagcgccaa accaggccag catttgagta caagatgggc cagattgcac accggtgaaa
    22021 tcgagaactt ta
//
LOCUS       DADXDL010000078        21932 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.078, whole genome shotgun sequence.
ACCESSION   DADXDL010000078 DADXDL010000000
VERSION     DADXDL010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21932)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21932)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21932
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.078"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..2448
                     /locus_tag="IRB70_003506"
     CDS             <1..2448
                     /locus_tag="IRB70_003506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YadA-like family protein"
                     /protein_id="HBC0633372.1"
                     /translation="DSLLWNATAGAFSAKHGTNGTDSKITNLLAGTVSSDSTDAINGS
                     QLYGLADSFTSYLGGGADISDAGVLTGPTYTIGGTDYNNVGDALAAINTSFSTSLGDA
                     LLWDATAKGGDGAFSAGRGKDNTASIITNVADGAISSTSSDAINGSQLYDTSKYIADT
                     LGGDAEVNADGTITAPTYAIAGGSYSNVGDALEAIDTTLDDALLWDATANDGAGAYNA
                     SHDGKASIITNVADGNIGEGSTDAINGSQLFNTNMMIQQNSEIINQLAGNTSETYIED
                     NGAGINYVRTNDNGLAFNDASASGIGATAVGYNSVAEGDSSVAIGQGSYSDVDTGIAL
                     GSSSVSSRVIVKGSRDTSVSEEGVVIGYDTTDGELLGALSIGDDGKYRQIINVADGSE
                     AHDAVTVRQLQNAIGAVATTPTKYFHANSTAEDSLAVGEDSLAMGAKTIVNGNAGIGI
                     GLNTLVLADAINGIAIGSNARANHANSIAMGNGSQTTRGAQTGYTAYNMDAPQNSVGE
                     FSVGSEDGQRQITNVAAGSADTDAVNVGQLKVTDAQVSQNTQSITNLNTQVTNLDTRV
                     TNIENGIGDIVSTGSTKYFKTNTDGVDANAQGKDSVAIGSGSIAAADNSVALGTGSVA
                     NEENTISVGSSTNQRRITNVAAGKNATDAVNVAQLKSSEAGGVRYDTKADGSVDYSNI
                     TLGGGNGGTTRISNVSAGVNNNDAVNYAQLKQSVQETKQYTDQRMVEMDNKLSKTESK
                     LSGGIASAMAMTGLPQAYTPGASMASIGGGTYNGESAVALGVSMVSANGRWVYKLQGS
                     TNSQGEYSAALGAGIQW"
     gene            2746..4401
                     /gene="lldP"
                     /locus_tag="IRB70_003507"
     CDS             2746..4401
                     /gene="lldP"
                     /locus_tag="IRB70_003507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate permease"
                     /protein_id="HBC0633373.1"
                     /translation="MNLWQQNYDPAGNIWLSSLIASLPILFFFFALIKLKLKGYVAAS
                     WTVAIALAVALLFYKMPVANALASVVYGFFYGLWPIAWIIIAAVFVYKISVKTGQFDI
                     IRSSILSITPDQRLQMLIVGFCFGAFLEGAAGFGAPVAITAALLVGLGFKPLYAAGLC
                     LIVNTAPVAFGAMGIPILVAGQVTGIDSFEIGQMVGRQLPFMTIIVLFWIMAIMDGWR
                     GIKETWPAVVVAGGSFAIAQYLSSNFIGPELPDIISSLVSLLCLTLFLKRWQPVRVFR
                     FGDLGASQVDMTLAHTGYTAGQVLRAWTPFLFLTATVTLWSIPPFKALFASGGALYEW
                     VINIPVPYLDKLVARMPPVVSEATAYAAVFKFDWFSATGTAILFAALLSIVWLKMKPS
                     DAISTFGSTLKELALPIYSIGMVLAFAFISNYSGLSSTLALALAHTGHAFTFFSPFLG
                     WLGVFLTGSDTSSNALFAALQATAAQQIGVSDLLLVAANTTGGVTGKMISPQSIAIAC
                     AAVGLVGKESDLFRFTVKHSLIFTCMVGVITTLQAYVLTWMIP"
     gene            4401..5177
                     /gene="lldR"
                     /locus_tag="IRB70_003508"
     CDS             4401..5177
                     /gene="lldR"
                     /locus_tag="IRB70_003508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator LldR"
                     /protein_id="HBC0633374.1"
                     /translation="MIVLPRRLSDEVADRVRALIDEKNLEAGMKLPAERQLAMQLGVS
                     RNSLREALAKLVSEGVLLSRRGGGTFIRWRHDTWSEQNIVQPLKTLMADDPDYSFDIL
                     EARYAIEASTAWHAAMRATPGEKEKIQLCFEATLSEDPDLASQADVRFHLAIAEASHN
                     IVLLQTMRGFFDVLQSSVKHSRQRMYLVPPVFSQLTEQHQAVIDAIFAGDADGARKAM
                     MAHLSFVHTTMKRFDEDQARHARITRLPGDHNEHSREKNA"
     gene            5174..6364
                     /gene="lldD"
                     /locus_tag="IRB70_003509"
     CDS             5174..6364
                     /gene="lldD"
                     /locus_tag="IRB70_003509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone-dependent L-lactate dehydrogenase"
                     /protein_id="HBC0633375.1"
                     /translation="MIISAASDYRAAAQRILPPFLFHYMDGGAYSEYTLRRNVEDLSE
                     VALRQRILKNMSDLSLETTLFNEKLSMPVALGPVGLCGMYARRGEVQAAKAADAHGIP
                     FTLSTVSVCPIEEVAPAIKRPMWFQLYVLRDRGFMRNALERAKAAGCSTLVFTVDMPT
                     PGARYRDAHSGMSGPNAAMRRYLQAVTHPQWAWDVGLNGRPHDLGNISAYLGKPTGLE
                     DYIGWLGNNFDPSISWKDLEWIRDFWDGPMVIKGILDPEDARDAVRFGADGIVVSNHG
                     GRQLDGVLSSARALPAIADAVKGDIAILADSGIRNGLDVVRMIALGADTVLLGRAFLY
                     ALATAGQAGVANLLNLIEKEMKVAMTLTGAKSISEITQDSLVQELSKAPAAALAPMAK
                     GNAA"
     gene            6412..6885
                     /gene="trmL"
                     /locus_tag="IRB70_003510"
     CDS             6412..6885
                     /gene="trmL"
                     /locus_tag="IRB70_003510"
                     /EC_number="2.1.1.-"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBC0633376.1"
                     /translation="MLNIVLYEPEIPPNTGNIIRLCANTGFRLHLIEPMGFAWDDKRL
                     RRAGLDYHEFTAVTRHHDYRAFLEAENPQRLFALTTKGTPAHSAVSYQDGDYLMFGPE
                     TRGLPASILDALPAEQKIRIPMVPDSRSMNLSNAVSVVVYEAWRQLGYPGAVLRD"
     gene            complement(6938..7759)
                     /gene="cysE"
                     /locus_tag="IRB70_003511"
     CDS             complement(6938..7759)
                     /gene="cysE"
                     /locus_tag="IRB70_003511"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001112113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBC0633377.1"
                     /translation="MSCEELEIVWNNIKAEARTLADCEPMLASFYHATLLKHENLGSA
                     LSYMLANKLSSPIMPAIAIREVVEEAYAADPEMIASAACDIQAVRTRDPAVDKYSTPL
                     LYLKGFHALQAYRIGHWLWNQGRRALAIFLQNQVSVTFQVDIHPAAKIGRGIMLDHAT
                     GIVVGETAVIENDVSILQSVTLGGTGKSGGDRHPKIREGVMIGAGAKILGNIEVGRGA
                     KIGAGSVVLQPVPPHTTAAGVPARIVGKPDSDKPSMDMDQHFNGINHTFEYGDGI"
     gene            complement(7839..8858)
                     /gene="gpsA"
                     /locus_tag="IRB70_003512"
     CDS             complement(7839..8858)
                     /gene="gpsA"
                     /locus_tag="IRB70_003512"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBC0633378.1"
                     /translation="MNQRNASMTVIGAGSYGTALAITLARNGHEVVLWGHDPEHIATL
                     ERDRCNAAFLPDVPFPDTLHLESDLATALAASRNILVVVPSHVFGEVLRQIKPLMRPD
                     ARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
                     QTFADDLQQLLHCGKSFRVYSNPDFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTAL
                     ITRGLAEMSRLGAALGADPATFMGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVQSA
                     QEKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNAREAALTLLGRARKD
                     ERSSH"
     gene            complement(8858..9325)
                     /gene="secB"
                     /locus_tag="IRB70_003513"
     CDS             complement(8858..9325)
                     /gene="secB"
                     /locus_tag="IRB70_003513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015369180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-export chaperone SecB"
                     /protein_id="HBC0633379.1"
                     /translation="MSEQNNTEMTFQIQRIYTKDISFEAPNAPHVFQKDWQPEVKLDL
                     DTASSQLADDVYEVVLRVTVTASLGEETAFLCEVQQGGIFSIAGIEGTQMAHCLGAYC
                     PNILFPYARECITSMVSRGTFPQLNLAPVNFDALFMNYLQQQAGEGTEEHQDA"
     gene            complement(9388..9639)
                     /gene="grxC"
                     /locus_tag="IRB70_003514"
     CDS             complement(9388..9639)
                     /gene="grxC"
                     /locus_tag="IRB70_003514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin 3"
                     /protein_id="HBC0633380.1"
                     /translation="MANVEIYTKETCPYCHRAKALLSSKGVSFQELPIDGNAAKREEM
                     IKRSGRTTVPQIFIDAQHIGGCDDLYALDARGGLDPLLK"
     gene            complement(9781..10212)
                     /locus_tag="IRB70_003515"
     CDS             complement(9781..10212)
                     /locus_tag="IRB70_003515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312516.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBC0633381.1"
                     /translation="MQEIMQFVGRHPILSIAWIALLVAVIVTTFKSLTSKVKVITRGE
                     ATRLINKEDAVVVDLRQRDDFRKGHIAGSINLLPSEIKANNVGELEKHKDKPVIVVDG
                     SGMQCQEPANALTKAGFAQVFVLKEGVAGWAGENLPLVRGK"
     gene            10457..12001
                     /gene="gpmM"
                     /locus_tag="IRB70_003516"
                     /gene_synonym="pgmI"
     CDS             10457..12001
                     /gene="gpmM"
                     /locus_tag="IRB70_003516"
                     /gene_synonym="pgmI"
                     /EC_number="5.4.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-independent
                     phosphoglycerate mutase"
                     /protein_id="HBC0633382.1"
                     /translation="MSVSKKPMVLVILDGYGYREEQQDNAIFSAKTPVMDALWANRPH
                     TLIDASGLEVGLPDRQMGNSEVGHVNLGAGRIVYQDLTRLDVEIKDRAFFANPVLTGA
                     VDKAKNAGKAVHIMGLLSAGGVHSHEDHIMAMVELAAERGAEKIYLHAFLDGRDTPPR
                     SAESSLKKFEEKFAALGKGRVASIIGRYYAMDRDNRWDRVEKAYDLLTLAQGEFQADT
                     AVAGLQAAYARDENDEFVKATVIRAEGQPDVAMEDGDALIFMNFRADRAREITRAFVN
                     ADFDGFARKKVVNVDFVMLTEYAADIKTAVAYPPASLVNTFGEWMAKNDKTQLRISET
                     EKYAHVTFFFNGGVEESFKGEDRILINSPKVATYDLQPEMSSAELTEKLVAAIKSGKY
                     DTIICNYPNGDMVGHTGVMEAAVKAVEALDHCVEEVAKAVESVGGQLLITADHGNAEQ
                     MRDPATGQAHTAHTNLPVPLIYVGDKNVKAVEGGKLSDIAPTMLSLMGMEIPQEMTGK
                     PLFIVE"
     gene            12011..13294
                     /gene="envC"
                     /locus_tag="IRB70_003517"
     CDS             12011..13294
                     /gene="envC"
                     /locus_tag="IRB70_003517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein hydrolase activator EnvC"
                     /protein_id="HBC0633383.1"
                     /translation="MRGKAINTMTRAVKPRRFAIRPIIYASVLSAGVLLCAFSAHADE
                     RDQLKSIQADIAAKERAVRQKQQQRASLLAQLKKQEEAISEATRKLRETQNTLNQLNK
                     QIDEMNASIAKLEQQKAAQERSLAAQLDAAFRQGEHTGIQLILSGEESQRGQRLQAYF
                     GYLNQARQETIAQLKQTREEVAMQRAELEEKQSEQQTLLYEQRAQQAKLTQALSERKK
                     TLAGLESSIQQGQQQLSELRANESRLRNSIARAEAAAKARAEREAREAQAVRDRQKEA
                     TRKGTTYKPTESEKSLMSRTGGLGAPRGQAFWPVRGPTLHRYGEQLQGELRWKGMVIG
                     ASEGTEVKAIADGRVILADWLQGYGLVVVVEHGKGDMSLYGYNQSALVSVGSQVRAGQ
                     PIALVGSSGGQGRPSLYFEIRRQGQAVNPQPWLGR"
     gene            13298..14257
                     /locus_tag="IRB70_003518"
     CDS             13298..14257
                     /locus_tag="IRB70_003518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312519.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="divergent polysaccharide deacetylase family
                     protein"
                     /protein_id="HBC0633384.1"
                     /translation="MFPFRRNVLAFAALLALSSPVIAGKLAIVIDDFGYRPHNENQVL
                     AMPSAISVAVLPDSPHAREMATKAHNSGHEVLIHLPMAPLSKQPLEKNTLRPEMSSDE
                     IERIIRSAVNNVPYAVGINNHMGSKMTSNLFGMQKVMQALERYNLYFLDSVTIGNTQA
                     MRAAQGTGVKVIKRKVFLDDSQNEADIRVQFNRAIDLARRNGSTIAIGHPHPSTVRVL
                     QQMVYNLPPDITLVKASSLLNEPQVDTSTPPKNTVPDAPRNPFRGVKLCKPKKPLEPV
                     YANRFFEVLSESISQSTLIVYFQHQWQGWGKQPEAAKLNASAN"
     gene            complement(14244..15278)
                     /gene="waaH"
                     /locus_tag="IRB70_003519"
     CDS             complement(14244..15278)
                     /gene="waaH"
                     /locus_tag="IRB70_003519"
                     /EC_number="2.4.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucuronate:LPS(HepIII) glycosyltransferase"
                     /protein_id="HBC0633385.1"
                     /translation="MMNSTNKLSVIIPLYNAGNDFRTCMESLIAQTWTALEIIIINDG
                     STDNSVEIAKHYAENYPHVRLLHQANAGASVARNRGIEVATGKYVAFVDADDEVYPTM
                     YETLMTMALEDDLDVAQCNADWCFRETGETWQSIPTDRLRSTGVLTGPDWLRMGLSSR
                     RWTHVVWMGVYRRDVIVKNNIKFIAGLHHQDIVWTTEFMFNALRARYTEQSLYKYYLH
                     NTSVSRLNRQGNKNLNYQRHYIKITRLLEKLNRNYADKITIYPEFHQQITYEALRVCH
                     AVRKEPDIITRQRMIAEIFTSGMYKRLITNVRSVKVGYQALLWSFRLWQWRDKTRSHH
                     RITRSAFNLR"
     gene            complement(15517..16542)
                     /gene="tdh"
                     /locus_tag="IRB70_003520"
     CDS             complement(15517..16542)
                     /gene="tdh"
                     /locus_tag="IRB70_003520"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005120462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBC0633386.1"
                     /translation="MKALSKLKAEEGIWMTDVPVPELGHNDLLIKIRKTAICGTDVHI
                     YNWDEWSQKTIPVPMVVGHEYVGEVVGIGQEVKGFKIGDRVSGEGHITCGHCRNCRGG
                     RTHLCRNTTGVGVNRPGCFAEYLVIPAFNAFKIPDNISDDLASIFDPFGNAVHTALSF
                     DLVGEDVLVSGAGPIGIMAAAVAKHVGARNVVITDVNEYRLELARKMGITRAVNVAKE
                     NLNDVMTELGMTEGFDVGLEMSGAPPAFRTMLDTMNHGGRIAMLGIPPSDMSIDWTKV
                     IFKGLFIKGIYGREMFETWYKMAALIQSGLDLSPIITHRFSIDDFQKGFDAMRSGQSG
                     KVILSWD"
     gene            complement(16552..17748)
                     /gene="kbl"
                     /locus_tag="IRB70_003521"
     CDS             complement(16552..17748)
                     /gene="kbl"
                     /locus_tag="IRB70_003521"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020239151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBC0633387.1"
                     /translation="MRGEFYQQLTNDLETARAEGLFKEERIITSAQQADITVADGSHV
                     INFCANNYLGLANHPDLIAAAKAGMDSHGFGMASVRFICGTQDSHKELEQKLAAFLGM
                     EDAILYSSCFDANGGLFETLLGAEDAIISDALNHASIIDGVRLCKAKRYRYANNDMQE
                     LEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVGFV
                     GENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSRPYLFSNS
                     LAPAIVAASIKVLEMVEAGSELRDRLWANARQFREQMSAAGFTLAGADHAIIPVMLGD
                     AVVAQKFARELQKEGIYVTGFFYPVVPKGQARIRTQMSAAHTPEQITRAVEAFTRIGK
                     QLGVIA"
     gene            17962..18894
                     /gene="rfaD"
                     /locus_tag="IRB70_003522"
     CDS             17962..18894
                     /gene="rfaD"
                     /locus_tag="IRB70_003522"
                     /EC_number="5.1.3.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-glyceromanno-heptose 6-epimerase"
                     /protein_id="HBC0633388.1"
                     /translation="MIIVTGGAGFIGSNIVKALNDKGITDILVVDNLKDGTKFVNLVD
                     LDIADYMDKEDFLIQIMAGEEFGDVEAIFHEGACSSTTEWDGKYMMDNNYQYSKELLH
                     YCLEREIPFLYASSAATYGGRTSDFIESREYEKPLNVYGYSKFLFDEYVRQILPEANS
                     QIVGFRYFNVYGPREGHKGSMASVAFHLNTQLNNGESPKLFEGSENFKRDFVYVGDVA
                     DVNLWFLENGVSGIFNLGTGRAESFQAVADATLAYHKKGQIEYIPFPDKLKGRYQAFT
                     QADLTNLRAAGYDKPFKTVAEGVTEYMAWLNRDA"
     gene            18904..19950
                     /gene="rfaF"
                     /locus_tag="IRB70_003523"
     CDS             18904..19950
                     /gene="rfaF"
                     /locus_tag="IRB70_003523"
                     /EC_number="2.4.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-heptose--LPS heptosyltransferase RfaF"
                     /protein_id="HBC0633389.1"
                     /translation="MKILVIGPSWVGDMMMSQSLYRTLQARYPQAIIDVMAPAWCRPL
                     LSRMPEVNEAIPMPLGHGALEIGERRKLGHSLREKRYDRAYVLPNSFKSALVPFFAGI
                     PHRTGWRGEMRYGLLNDVRVLNKEAWPLMVERYVALAYDKGIMRTAQDLPQPLLWPQL
                     QVSEGEKSYTCNQFSLSSERPMIGFCPGAEFGPAKRWPHYHYAELAKQLIDEGYQVVL
                     FGSAKDHEAGNEILAALNTEQQAWCRNLAGETQLDQAVILIAACKAIVTNDSGLMHVA
                     AALNRPLVALYGPSSPDFTPPLSHKARVIRLITGYHKVRKGDAAEGYHQSLIDITPQR
                     VLEELNALLLQEEA"
     gene            19954..20913
                     /gene="rfaC"
                     /locus_tag="IRB70_003524"
     CDS             19954..20913
                     /gene="rfaC"
                     /locus_tag="IRB70_003524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide heptosyltransferase RfaC"
                     /protein_id="HBC0633390.1"
                     /translation="MRVLIVKTSSMGDVLHTLPALTDAQQAIPGIKFDWVVEEGFAQI
                     PSWHAAVERVIPVAIRRWRKAWFSAPIKAERKAFREALQAENYDAVIDAQGLVKSAAL
                     VTRLAHGVKHGMDWQTAREPLASLFYNRKHHIAKQQHAVERTRELFAKSLGYSKPQTQ
                     GDYAIAQHFLTNRPTDAGEYAVFLHATTRDDKHWPEEHWRELIGLLADSGIRIKLPWG
                     APHEEERAKRLAEGFAYVEVLPKMSLEGVARVLAGAKFVVSVDTGLSHLTAALDRPNI
                     TVYGPTDPGLIGGYGKNQMVCRAPLKSLNNLEAAAVYKKITLI"
     gene            complement(20961..>21932)
                     /locus_tag="IRB70_003525"
     CDS             complement(20961..>21932)
                     /locus_tag="IRB70_003525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000453195.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBC0633391.1"
                     /translation="GYLESGKLLVFSSLTFLLLSKNKFRQNEKLHFISAILVQIIMLC
                     RAYYQGIYLHADRIPLSAMNGNIGQMGAATIAAYVITFTTLYSSIVFIKMQSKYKWFL
                     FYANFALSFAAVMMTGTRAAIFTFPLMIMVILFLQHRDQKVFLFKGLSGVFILLLACG
                     LIFNKEIDRRINSLKADVISYATKNNSQSSVGARFAMVNAGIKGSPDGFNWQSLEQRA
                     EKIKALSAENNIYSGALLFLDVHMHNEIVESLSTKGKIGLLVLIMFYVAMIYYCIREK
                     KYILLVFPASIMLFGISDVITHAKPIPASWIVCLFLSISFLSKKEPQ"
BASE COUNT         5428 a         5719 c         5647 g         5138 t
ORIGIN      
        1 gattccctgc tgtggaacgc tacggcgggt gcattcagtg ccaaacacgg caccaacggt
       61 actgacagca aaatcaccaa cttactggca ggcactgtat cctctgatag cactgacgcc
      121 attaatggct cacaacttta tggtttagct gattcattta cgtcatacct tggcggtggt
      181 gctgatatca gcgatgcggg tgtattaacc gggccaacct acactattgg tggtactgac
      241 tacaataacg tcggtgatgc tctggcagcc attaacacgt catttagcac atcactcggt
      301 gacgccctac tctgggatgc gaccgccaag ggcggtgacg gtgcgtttag cgccggtcgc
      361 ggaaaagata acacggccag catcattact aatgttgcag acggtgcaat ttcctctacc
      421 agcagcgacg ctattaacgg ctcacagctc tatgacacca gtaagtacat tgccgatact
      481 ctgggtggtg acgcagaagt caatgctgac ggcacaatca ccgcaccgac ttatgccatc
      541 gctggcggca gttacagcaa cgtcggtgac gcgctggaag cgatcgatac cacgctggat
      601 gacgctctgt tgtgggatgc cacagccaat gacggcgcag gtgcctacaa cgccagccat
      661 gacggcaagg ccagcatcat cacaaatgtt gctgatggta acattggcga aggcagtacc
      721 gacgccatca acggttctca gctgtttaac accaatatga tgatccagca gaacagcgaa
      781 atcatcaatc agcttgccgg taacaccagc gaaacctaca tcgaagataa cggtgcgggt
      841 attaactatg tacgtaccaa cgacaacggc ttagcgttca acgatgccag cgcttcaggt
      901 attggcgcta cggctgtggg ttataactct gttgccgaag gcgatagcag cgtagccatc
      961 ggtcagggca gctacagcga cgttgatacc ggtattgccc tgggtagcag ctccgtttcc
     1021 agccgtgtaa tagttaaagg ttctcgtgac accagcgtgt cggaagaagg tgttgtgatt
     1081 ggttatgaca ccacggatgg cgaactactt ggtgcgctgt ctattggtga tgacggtaaa
     1141 tatcgtcaaa tcatcaacgt agccgatggt tccgaagccc atgacgccgt tacggttcgc
     1201 cagttgcaaa atgccattgg tgcagtcgct accacgccga ccaaatactt ccacgccaac
     1261 tcaacggctg aagactcact ggctgtcggg gaagactcgc tggcgatggg cgcgaaaact
     1321 atcgtcaatg gtaatgcggg tattggtatc ggcctgaata ctctggttct ggcagatgcc
     1381 atcaacggta ttgctatcgg ttctaacgca cgcgccaacc atgcaaacag tattgcaatg
     1441 ggtaatggtt ctcagaccac tcgcggcgct cagactggct acaccgccta caacatggat
     1501 gcaccgcaga actctgtggg tgaattctcc gtaggtagcg aagacggtca acgtcagatc
     1561 accaacgtcg cagcggggtc ggcggatacc gatgcggtta acgtgggtca gttgaaagta
     1621 acggacgcgc aggtttccca gaatacccag agcattacta acctgaatac tcaggtaacg
     1681 aatctggata cccgcgtcac caatatcgaa aacggtattg gcgatatcgt aagcaccggt
     1741 agcaccaagt acttcaagac caacaccgat ggcgtagatg ctaacgcgca gggtaaagac
     1801 agtgttgcga ttggctctgg ctctattgct gccgctgata acagcgttgc gctgggtact
     1861 ggctctgtgg caaacgaaga aaatacgatc tccgtaggtt cttccactaa ccaacgccgt
     1921 atcaccaacg ttgccgctgg taaaaatgct actgacgcgg ttaacgttgc gcagttgaag
     1981 tcttccgaag caggcggcgt gcgctatgac accaaagctg acggttctgt tgattacagc
     2041 aacatcactc tcggcggtgg taatggcgga acgactcgca ttagcaacgt ttccgctggc
     2101 gttaacaaca acgacgcagt gaactatgcg cagttgaagc aaagcgtgca ggaaacgaag
     2161 caatacaccg atcagcggat ggttgagatg gataacaaac tgtccaaaac cgaaagcaag
     2221 ttgagcggtg gtatcgcttc tgcaatggca atgaccggtc tgccgcaggc ttacactcca
     2281 ggtgccagta tggcctctat tggtggcggt acttacaacg gtgaatcggc tgttgcttta
     2341 ggtgtgtcga tggtgagcgc caatggtcgt tgggtctaca aattacaagg tagtaccaat
     2401 agccagggtg aatactccgc cgcactcggt gccggtattc agtggtaatg atccattaac
     2461 ttagtgtgac taagggcaat tctctgatga ggattgccct tttctttacc agacatctcc
     2521 ctccaccaag aattggccct accaattctt cgcttatctg acctctggtt cacaattccc
     2581 caattaaaac tcacatcaat gttgctaatg cataacattt agttaactat ccattgtcat
     2641 tatccctaca caacacaatt ggcagtgcca cttttacaca acgtgtgaca aggagatgag
     2701 caacagactc attacactgc gtgtgtggac tgcaggagac ctgcaatgaa tctctggcaa
     2761 caaaactacg atcccgccgg gaatatctgg ctttccagcc tgatagcatc gcttcccatc
     2821 ctgtttttct tctttgcgct gattaagctc aaactgaaag gatacgtcgc cgcctcatgg
     2881 acggtggcaa tcgcccttgc cgtggctttg ctgttctata aaatgccggt cgctaacgcg
     2941 ctggcctcgg tggtttatgg cttcttctac gggttgtggc ccatcgcgtg gatcattatt
     3001 gcggcagtgt tcgtctataa gatctcggtg aaaaccgggc agtttgacat catccgctcg
     3061 tctattcttt cgataacccc tgaccagcgc ctgcaaatgc tgatcgtcgg tttctgtttc
     3121 ggcgctttcc ttgaaggagc cgcaggcttt ggcgcaccgg tagcaattac cgccgcattg
     3181 ctggtcggtc tgggctttaa accactctac gccgccggac tgtgcctgat tgttaacacc
     3241 gcaccagtgg catttggcgc gatgggtatt ccgattctgg tcgccgggca ggtaacaggc
     3301 atcgacagct ttgagattgg tcagatggtg gggcgtcagc tgccgtttat gaccattatc
     3361 gtgctgttct ggatcatggc gattatggac ggttggcgcg gtatcaaaga gacgtggcct
     3421 gcggtcgtgg ttgcaggtgg ttcgtttgcc attgctcaat acctcagctc taacttcatt
     3481 gggccggaac tgccagacat tatctcttcg ctggtatcac tgctctgcct gacgctgttc
     3541 ctcaaacgct ggcaaccagt gcgcgtattc cgcttcggtg acttgggggc gtcacaggtt
     3601 gatatgacgc tggctcacac aggttacacg gcaggtcagg tgctgcgcgc ctggacaccg
     3661 tttctgttcc tgaccgccac cgtaacgctg tggagtatcc cgccgtttaa agccctgttc
     3721 gcttcaggcg gtgcgctgta tgagtgggtg atcaacattc cggtgccgta cctcgataaa
     3781 ctggttgccc gtatgccgcc agtggtcagc gaagcgacag cgtatgccgc cgtgtttaag
     3841 tttgactggt tctctgccac cggtaccgcc attctgtttg ctgccctgct ctcgattgtc
     3901 tggctgaaga tgaaaccatc tgacgctatc agcaccttcg gcagcacgct gaaagaactg
     3961 gctctgccca tctactccat cggtatggtg ctggcattcg cctttatctc gaactattcc
     4021 ggtttgtcat caacactggc gctggcactg gcgcacaccg gtcatgcatt caccttcttc
     4081 tcgccgttcc tcggctggct tggtgtcttc ctgaccggat cggatacctc atctaacgcc
     4141 ctgttcgccg ccctgcaagc cactgcagca caacaaattg gcgtttctga cctgttgctg
     4201 gttgctgcca acaccaccgg tggtgtcacc ggcaaaatga tctctccgca atctatcgct
     4261 atcgcctgtg cggcggtagg cctggtgggc aaagagtctg atttgttccg ctttactgtc
     4321 aaacacagcc tgatcttcac ctgtatggtg ggcgtgatca ccacgcttca ggcctatgtc
     4381 ttaacgtgga tgattcctta atgattgttt tacccagacg cctgtcagac gaggttgccg
     4441 atcgtgtgcg ggcgctgatt gatgaaaaaa acctggaagc gggcatgaag ttgcccgctg
     4501 aacgtcaact ggcgatgcaa ctcggcgtgt cgagaaattc actgcgcgag gcgctggcga
     4561 aactggtaag cgaaggtgtg ctgctcagtc gacgtggcgg cgggacgttt attcgctggc
     4621 gtcatgacac atggtcggag caaaacatcg tccagccgct gaaaacgctg atggccgatg
     4681 atccggatta cagtttcgat attctggaag cccgctacgc cattgaagcc agcaccgcgt
     4741 ggcatgcggc aatgcgcgcc acaccaggcg aaaaagagaa aattcagctt tgctttgaag
     4801 caacgctaag tgaagacccg gatctcgcct cacaagcgga cgttcgtttt catctggcga
     4861 ttgccgaagc ctcacataac atcgtgctgc tgcaaaccat gcgcggtttc ttcgatgtcc
     4921 tgcaatcctc cgtgaagcat agccgccagc ggatgtatct ggtacccccg gttttttcac
     4981 agctgaccga acaacatcag gcagtcattg acgccatttt tgccggtgat gctgacgggg
     5041 cgcgtaaagc aatgatggcg caccttagct ttgttcacac taccatgaaa cgattcgatg
     5101 aagatcaagc tcgccatgca cgcattaccc gcctgcctgg tgaccataat gagcattcga
     5161 gggagaaaaa cgcatgatta tttccgcagc cagcgattat cgcgccgcag cacaacgcat
     5221 tctgccgccg ttcctgttcc actatatgga tgggggggca tattctgaat acacgctgcg
     5281 ccgcaacgtg gaagatttgt cagaagtggc gctgcgccag cgtattctga aaaacatgtc
     5341 tgacttaagc ctggaaacga cgctgtttaa tgagaaattg tcgatgccgg tggcgctagg
     5401 tccggtaggt ttgtgtggca tgtatgcgcg acgcggcgaa gttcaggctg ccaaagcagc
     5461 ggatgcgcat ggcattccgt ttactctctc gacggtttcc gtttgcccga ttgaagaagt
     5521 ggctccggct atcaaacgtc cgatgtggtt ccagctttat gtgctgcgcg atcgcggctt
     5581 tatgcgtaac gcactggagc gagcaaaagc agcgggttgt tcgacactgg ttttcaccgt
     5641 ggatatgccg acaccgggcg cacgttaccg tgatgcgcat tctgggatga gcggcccaaa
     5701 tgcggcaatg cgccgctact tgcaggcggt gacgcatccg caatgggcgt gggatgtggg
     5761 cctgaacggt cgtccgcatg atttaggtaa tatctcggct tacctcggca aaccgaccgg
     5821 actggaagat tacatcggct ggctggggaa taacttcgat ccgtccatct catggaaaga
     5881 ccttgagtgg atccgcgatt tctgggatgg cccgatggtg atcaaaggga tcctcgaccc
     5941 agaagatgcg cgcgatgcag tacgctttgg tgctgatgga attgtggttt ctaaccacgg
     6001 tggccgccag ctggacggtg tgctctcttc tgcccgtgca ctgcctgcta ttgcagatgc
     6061 ggtgaaaggt gatatcgcca ttctggcgga tagcggaata cgtaacgggc ttgatgtcgt
     6121 gcgtatgatt gcgctcggtg ccgacaccgt actgctgggt cgtgctttcc tgtatgcgct
     6181 ggcaacagcg ggccaggcgg gtgtagctaa cctgctaaat ctgatcgaaa aagagatgaa
     6241 agtggcaatg acgctgactg gcgcgaaatc gattagcgaa attacgcaag attcgctggt
     6301 gcaagagctg agtaaagcgc cggcggcggc gctggctcca atggcgaaag ggaatgcagc
     6361 ttaagggtta gatgaatatc tgctatcctg cccccgcact aagggggcag tatgctaaac
     6421 atcgtacttt acgaaccaga aattccgcca aatactggca acatcatccg tctttgcgct
     6481 aataccggct ttcgtctgca tctcatcgaa ccgatgggat ttgcctggga cgataagcgc
     6541 ctgcgccgcg cggggctgga ctatcacgag tttaccgccg ttacgcgtca tcatgactat
     6601 cgcgcgttcc ttgaagcaga aaatccccag cgcctgtttg ccctcaccac gaaaggtacg
     6661 cctgctcaca gcgccgtaag ctatcaggat ggcgattatc tgatgttcgg cccggaaaca
     6721 cgcggcctgc cagcgagcat tcttgatgcc ctgcccgctg aacaaaaaat tcgcattcca
     6781 atggtgccgg acagccgcag catgaacctg tccaatgcgg tgtcggtcgt ggtgtatgaa
     6841 gcctggcggc agctgggata tccgggagcg gtgttgagag attagttact gtatgccgga
     6901 tagatgatta catcgcatcc ggcacaatca caggacgtca gatcccatcc ccatattcaa
     6961 acgtatggtt aataccgttg aaatgctgat ccatatccat tgacggttta tcgctatccg
     7021 gtttgccgac aatgcgtgcc ggaacgccag cggcggtggt atgcggcggc accggttgca
     7081 gcaccacgga acctgcgcca atcttcgcgc cgcgcccaac ttcaatattg ccgagaattt
     7141 tcgcgcccgc gccaatcatc acaccttcac gaattttcgg atgacggtcg ccaccagatt
     7201 tacccgtacc gccaagcgtc acagattgca gaatcgatac gtcgttttca atcaccgccg
     7261 tttcacccac aacgatgccc gtggcgtggt caagcatgat accgcggcca atttttgctg
     7321 ccgggtgaat atcaacctgg aacgtcacag aaacctggtt ttgcagaaag attgccagtg
     7381 cgcgacgccc ctgattccac aaccagtggc cgatgcgata cgcctgcaaa gcatgaaaac
     7441 ccttcaggta tagcaacggg gttgagtatt tatccaccgc cgggtcacgg gtacgcaccg
     7501 cctgaatatc acaggccgca gaggcgatca tttccgggtc ggcggcgtag gcttcttcga
     7561 ccacttcacg gatagcaata gccggcataa tgggcgatga cagcttgttc gccagcatgt
     7621 agctcagtgc actgccaagg ttttcgtgct tgagtagcgt cgcgtggtaa aaactggcca
     7681 gcattggctc acagtctgcc agcgttctgg cttcagcttt aatattgttc cagacaattt
     7741 ccagttcttc acacgacatt gcttactcca cacgataaga taatgaccgg cccgttctgc
     7801 gcgggccggg tcatagtggt aacaaaggtt ccctgggttt agtggctgct gcgctcgtcc
     7861 ttgcgtgcac gacctagtaa agtcaatgct gcctcgcgcg cgttttttcc gcaatataat
     7921 acttgataaa tttcctcggt tattggcatt tcaacgccga agcgatgcgc cagttcgcgg
     7981 acttctttcg tattgcggta gccttccacc acttgaccaa ttttctcctg cgcgctttgt
     8041 acatccatgc cctgaccgag catcatgcca aaacggcggt tacgcgactg gttgtcggta
     8101 caggtcagca ccagatcgcc cagccccgcc atgcccataa aggtggcagg atcggcaccc
     8161 agcgccgcgc caagacgcga catctcagcc agcccacggg tgatcagcgc cgtacgcgca
     8221 ttcgcgccaa aaccgatacc gtcggacatc cccgcgccaa tggcaatgac gtttttcacc
     8281 gcgccgccaa gctgcacacc gatgaaatcc gggttgctgt aaacgcggaa acttttgcca
     8341 cagtgcagca attgctggag gtcatcggca aaggtctggt ccgtcgaggc cagcgaaatg
     8401 gccgtcggta aacctgccgc cagttctttc gcaaacgttg ggccagagat aaccgccagc
     8461 ggaatttgat cgcctaaggc ctcacgcgct acgtcctgta acagacgtcc ggtttctgct
     8521 tccagccctt tggtcgccca caccagacgc gcatcaggac gcatcagcgg tttaatctgg
     8581 cgcagcactt caccaaagac atggctgggt acgacgacga gaatattacg gctggctgcc
     8641 agcgcagtgg cgagatcgct ttcaagatgg agcgtatcgg gaaaaggcac atcggggaga
     8701 aacgcggcgt tacagcggtc gcgttcaagc gttgcgatat gttcagggtc atggccccag
     8761 aggacaacct cgtggccatt tcttgccagg gtaatggcaa gagcggtgcc gtacgagccg
     8821 gcaccgatca cagtcattga agcattacgt tggttcatca ggcatcctga tgttcttcag
     8881 taccttcgcc agcctgctgc tgcaaatagt tcatgaacag cgcatcgaag ttaaccggcg
     8941 caaggttcag ttgcgggaat gtaccgcggg ataccatgct ggtgatgcac tcacgagcat
     9001 acgggaacag aatgttcggg cagtatgcac ccaggcaatg tgccatctgg gtgccttcga
     9061 tacccgcgat ggagaaaata ccgccctgct gaacttcaca caggaacgcg gtttcttcgc
     9121 ccagggaggc cgttacggta acacgcagta ccacttcgta aacgtcatct gccagttgag
     9181 aagatgccgt atccagatca agtttaactt ctggctgcca atctttctgg aaaacgtgcg
     9241 gcgcgttcgg cgcttcgaaa gaaatatcct tggtataaat acgttggatc tggaaagtca
     9301 tttcggtgtt gttttgttct gacatgtgta gaaaaccctt aagtgttgtc cttaaatact
     9361 gcgcaatgta atgccaacgt tcacacgtta tttcagcagg ggatccagtc caccacgtgc
     9421 atccaatgca tacaagtcat cacagccgcc aatgtgctgt gcgtcaataa aaatctgggg
     9481 aaccgtggtg cgaccgctgc gtttgatcat ctcttcacgc ttagcggcgt tgccatcgat
     9541 cggcaactcc tgaaaactca cgcccttgct gctcagcagt gctttcgcac gatggcaata
     9601 cgggcaggtt tctttggtat agatttcaac attggccata acttagctcc tgttttttta
     9661 ccctgaaatt tcatgttgca gggcggctgc aaaatggagt gtccccagaa gcttataaca
     9721 ataagtcgct gggggcctaa ttgcagctaa cggcctgcat catgaaagac gacaggtaaa
     9781 ttatttgccg cgcaccagag gtaagttttc gccagcccag ccagcaacgc cctctttcag
     9841 cacgaatact tgcgcaaaac cagctttcgt cagcgcgttt gcaggctcct ggcactgcat
     9901 gccagaaccg tctaccacga taaccggttt gtctttgtgc ttctcaagct caccaacatt
     9961 gttggctttg atttcgctcg gcaacaggtt gatagaacct gcgatatggc ctttacggaa
    10021 gtcatcacgc tgacgtaaat ccacaaccac agcatcttct ttgttgatca gacgcgtagc
    10081 ttcaccacga gtaatcacct tcactttcga ggtcaggctc ttaaacgtag tcacaataac
    10141 cgccaccagt aacgcgatcc aggcgatact cagtatggga tgacggccaa caaattgcat
    10201 aatttcttgc atggggggta acaactcccg acgtagtgat taaaaaaacc aggaaaggag
    10261 tatacctgcg cgttgcggca aatacagcca gcgcgttaac tggaatgcaa ttttgcgggg
    10321 cgctacgaaa aaaaagcgta aatctggcat ctgcttgccg cgagcggtcg tatattttga
    10381 tcttcagagg ctattttatc gattcagctg tagtaaaatt acgcaaattt tgactcttga
    10441 gtatgaggtt gtcgcaatgt cggtttctaa aaaacctatg gtactggtga ttctggatgg
    10501 ctatggctat cgcgaagaac agcaggataa cgccattttt agtgctaaaa ccccggtaat
    10561 ggatgcactg tgggccaatc gtccgcatac cctgatcgac gcttccggtc tggaagtcgg
    10621 tctgcctgac cgtcagatgg gcaactccga agtaggccac gttaacctgg gtgccggccg
    10681 catcgtgtat caggacctga ctcgtctgga cgttgaaatc aaagatcgcg ctttctttgc
    10741 taatccggtg ttgactggtg cagtagataa agcgaaaaac gcaggcaaag cagtacacat
    10801 tatgggtctg ctctccgcag gtggtgtaca cagccacgaa gatcacatca tggcgatggt
    10861 agaactggca gctgaacgcg gcgcagaaaa aatctaccta cacgcattcc ttgacggtcg
    10921 cgacactccg ccgcgcagtg ctgaatcctc gctgaaaaaa ttcgaagaga aatttgccgc
    10981 gctgggtaaa ggccgcgtag cgtccatcat tggtcgttac tacgcgatgg accgcgataa
    11041 ccgttgggat cgcgttgaaa aagcttatga cctgctgact ctggcgcaag gtgagttcca
    11101 ggccgatacc gccgttgccg gtttgcaggc tgcttatgct cgcgacgaaa acgacgagtt
    11161 cgtgaaagcg accgttattc gtgcagaagg tcagccagat gtggcaatgg aagacggcga
    11221 tgcactgatt ttcatgaact tccgtgctga ccgcgcgcgt gaaatcactc gagcattcgt
    11281 aaatgccgat tttgacggct tcgcgcgtaa gaaagtggtt aacgtcgatt tcgtgatgct
    11341 gaccgaatac gctgccgaca tcaaaaccgc agtggcttac ccacccgctt ccctggttaa
    11401 caccttcggc gaatggatgg cgaaaaacga caaaactcag ctgcgtattt ccgaaaccga
    11461 aaaatatgcc cacgtcactt tcttctttaa cggtggcgta gaagagtcgt tcaaaggcga
    11521 agatcgcatt ctgatcaact caccgaaagt ggctacctac gatctgcaac cggaaatgag
    11581 ctccgcagag ctgaccgaaa aactggttgc ggcaatcaag agcggcaaat acgacaccat
    11641 tatctgtaac tatccgaacg gcgacatggt aggtcacacc ggggtgatgg aagcggcggt
    11701 taaagcggtt gaagcgctgg atcactgcgt ggaagaagtc gcgaaagcgg ttgagtccgt
    11761 gggtggacaa ctgctgatca ccgctgacca cggtaacgct gaacagatgc gcgatccggc
    11821 aacgggtcag gcgcacacag cacacaccaa cctgccagtt ccgctgattt acgttggtga
    11881 taagaacgtg aaagcggttg aaggcggcaa actttctgac atcgcgccga ccatgttgtc
    11941 gctgatgggt atggaaatcc cgcaagagat gactggtaag ccgctgttca tcgtggaata
    12001 atccctcccc atgaggggaa aggcgattaa taccatgaca cgggccgtga aaccgcgcag
    12061 gtttgcaatc aggcccatca tctacgccag cgttctgagc gctggcgtat tgttgtgcgc
    12121 cttttccgcc cacgcggatg agcgtgacca actcaaatcc attcaggctg acatcgccgc
    12181 gaaagagcgc gcggtacgcc aaaagcaaca acaacgcgca agcctgctcg cacaattgaa
    12241 aaagcaggaa gaggcgatat ctgaagccac tcgcaaactg cgcgaaacgc aaaatacgct
    12301 caatcaactc aataaacaga ttgatgagat gaacgcgtcg attgccaaac tggagcagca
    12361 aaaagccgcc caggagcgca gcctcgccgc gcaactggat gccgcgtttc gtcagggtga
    12421 acataccggt attcagctga ttctcagcgg tgaagaaagc cagcgtgggc agcgcttaca
    12481 ggcttatttc ggctatctca accaggcgcg acaagaaacc attgctcagt tgaaacaaac
    12541 gcgtgaagaa gtcgctatgc agcgtgccga actggaagag aaacagagcg agcaacaaac
    12601 gcttttatat gagcagcgcg cccaacaggc gaagctgacc caggcgttga gcgagcgtaa
    12661 aaagacgctg gcagggctgg agtcttccat ccagcaaggt cagcaacagt tgagcgagct
    12721 gcgcgccaac gaatcccgcc tgcgtaacag cattgcccgt gcggaagctg cggcgaaagc
    12781 gcgtgctgaa cgagaagcgc gtgaggccca ggcggttcgc gaccgccaga aagaagcgac
    12841 gcgcaaaggc accacctaca agccgaccga aagcgaaaaa tcgctgatgt cccgaactgg
    12901 tggcctgggt gcgccgcgtg gtcaggcatt ctggccggtt cgcgggccga cgctgcatcg
    12961 ctatggtgaa cagctacagg gcgaactacg ctggaaagga atggttatcg gtgcctctga
    13021 aggtactgaa gttaaagcga ttgccgacgg ccgggtgatt ctggctgact ggctgcaagg
    13081 ctacggtctg gtggtggtgg ttgagcacgg taaaggcgac atgagtcttt acggctataa
    13141 tcagagcgca ctggtgagcg ttggttcgca ggttcgcgcg ggccagccaa ttgcactggt
    13201 gggcagcagt ggcggtcagg gtcggccttc actctatttc gaaattcgcc gccagggtca
    13261 ggcggtcaat ccacagccgt ggttgggaag ataagttttg tttccatttc gtcgtaacgt
    13321 tcttgcattt gccgctctgt tggcgctctc ctcccccgta attgctggca aacttgccat
    13381 cgtcattgat gattttgggt atcgcccgca caacgaaaac caggtgctgg cgatgccttc
    13441 cgctatctcc gtcgctgtat tacccgattc accgcacgcc agagagatgg cgaccaaagc
    13501 gcataacagc ggtcacgaag tgttgattca tctcccgatg gcaccgttga gtaaacagcc
    13561 gctggagaaa aatacgctgc gcccggagat gagcagcgac gaaattgagc gcattattcg
    13621 tagtgcggtc aataacgtgc cctatgccgt ggggatcaat aaccacatgg gcagcaagat
    13681 gacctctaac ctgtttggta tgcagaaagt gatgcaggcg ctggagcgtt acaatcttta
    13741 cttcctcgac agcgtaacca tcggtaatac ccaggcgatg cgcgccgcgc aaggcactgg
    13801 cgtgaaggtg atcaaacgga aggtgttcct cgacgattcg cagaacgaag cggacatccg
    13861 tgtacagttt aatcgcgcaa ttgacctggc gcgtcgcaac ggatcaacca ttgccattgg
    13921 gcatcctcac ccttcaacgg tacgcgtgct acaacagatg gtttataacc tgccgccaga
    13981 cattacgctg gtgaaagcca gcagcttgct gaatgaaccg caggttgata cgtctacacc
    14041 gccgaaaaac actgtgcccg acgcaccgcg taatccgttc cgtggcgtga agctctgcaa
    14101 accgaagaaa ccgctggaac ctgtttatgc taatcgcttc tttgaagtat taagcgaaag
    14161 catcagccag agcacgctga tcgtttactt ccagcatcag tggcaaggct ggggcaaaca
    14221 gcctgaagcg gcgaagctta acgctagcgc aaattaaagg cgctacgcgt aatgcgatgg
    14281 tgcgaccgcg ttttgtcgcg ccattgccat aagcggaaag accacagtaa cgcctgataa
    14341 cccaccttca cgctgcgcac attggtaatc aggcgcttat acataccgga agtaaatatc
    14401 tcggcaatca tccgttggcg ggtaataata tccggctctt tgcgcaccgc atggcaaaca
    14461 cgcaatgctt cgtaggttat ttgctgatga aattccggat aaatcgtaat tttgtcagca
    14521 taatttcgat ttaatttctc cagcaggcgg gtaatcttaa tatagtgacg ttgataatta
    14581 aggtttttgt tcccttgtct gttcaaccga ctcactgacg tattatgcag ataatattta
    14641 tataatgatt gctcggtata tcgcgcacgc agcgcgttaa acataaattc tgttgtccag
    14701 acaatatcct gatgatgtaa tccggcaata aatttaatgt tatttttaac aataacatcg
    14761 cggcgataaa cccccatcca gaccacgtgt gtccaacggc gggaagaaag tcccatccgc
    14821 agccagtccg gaccagttaa tacaccggtt gagcgaaggc gatcggtagg gatggattgc
    14881 caggtttcac ccgtttcacg aaaacaccaa tcagcgttgc actgcgccac gtcgaggtcg
    14941 tcctctaacg ccatggtcat cagcgtttcg tacatggtgg gatagacctc atcgtcagca
    15001 tcgacaaaag cgacatattt tcccgttgcc acctcgatcc cacgattacg cgccaccgat
    15061 gcgccagcat tcgcctgatg caacaaacga acgtgcggat agttttctgc gtaatgcttt
    15121 gctatttcaa cagaattatc cgttgaacca tcgttaataa taatgatttc cagagcagtc
    15181 catgtttgcg caattaaaga ttccatacaa gtgcggaaat cattgcccgc attatataac
    15241 ggaataataa cactaagttt attggtgctg ttcatcataa attaccgacg acctctgaag
    15301 ttatcctgac gttttacagg ctttgtatta agaaactatt aagcctgtga gatattattt
    15361 ttaccggtga gagagtcacg tcagggtaga gagataatga gagcagctat ataagagatc
    15421 agcgcaatta cgatatcttg attacactga caggatttta catatttaac ggattatcct
    15481 caggaaaaag ggctggaata ccagcccttg tttgtgttaa tcccagctca ggataacttt
    15541 cccggactgg cccgaacgca tggcgtcaaa gcccttctgg aaatcatcga tagagaaacg
    15601 atgagtaatg atcggcgaaa gatcgaggcc agactgaatc agcgccgcca tcttgtacca
    15661 ggtttcaaac atctcacgac cgtaaatacc tttaatgaac aagcctttaa agatcacttt
    15721 ggtccagtcg atagacatat cagacggtgg aatacccagc atcgcaatac gaccgccgtg
    15781 gttcatggtg tcgagcatgg tacgaaacgc tggcggcgca ccggacattt ccagaccgac
    15841 atcaaagcct tcggtcatgc ccagttctgt catcacatca ttaaggtttt ctttcgcgac
    15901 gttaaccgca cgggtgatac ccattttacg cgccagctca aggcggtatt cgttaacatc
    15961 agtaatcacc acgttacgtg caccaacgtg tttcgccacc gccgcagcca taatacctat
    16021 cggacctgca ccagaaacca gtacatcttc gcccaccaga tcgaacgaca gcgcagtatg
    16081 cacggcgtta ccgaacggat caaaaatgga agccaaatcg tcggagatat tgtcagggat
    16141 tttgaaggcg ttgaacgccg gaatcaccag atattcggcg aagcagcccg gacggttaac
    16201 accgacacca gtggtgttgc ggcacagatg ggtacgaccg ccacgacagt tgcgacagtg
    16261 accgcaagtg atatggcctt caccagatac gcgatcgcca atcttgaagc ctttcacttc
    16321 ctgaccaata cctaccactt caccgacata ttcatggccc acgaccatcg gcaccgggat
    16381 ggttttttgc gaccactcat cccagttata gatgtgaacg tcagtcccgc agatggctgt
    16441 tttacggatt ttaatcagca gatcgttatg cccgagttcc ggtacaggaa cgtcggtcat
    16501 ccagatgccc tcttccgctt tcagtttgga taacgctttc atctcacatc ctcaggcgat
    16561 aacgcccagt tgtttaccaa tacgcgtgaa tgcttctact gcacgcgtaa tttgctcagg
    16621 ggtatgcgcc gcagacatct gggtacgaat acgcgcctga cctttcggaa cgaccggata
    16681 gaagaaaccg gtgacgtaaa tcccctcttt ttgcagctca cgagcaaatt tctgcgctac
    16741 taccgcatcg ccaagcatga ccggaataat ggcgtgatcg gctcccgcca gggtaaagcc
    16801 cgccgccgac atttgctcac ggaactgacg cgcgttcgcc cacagacggt cacgcagctc
    16861 gctacccgct tcaaccatct ccagcacttt gatggaagcg gcaacaatgg ccggtgccag
    16921 cgagttggag aacaggtacg gacgagaacg ctggcgcagc cactcaacca cttctttgcg
    16981 cgccgcggta taaccaccag aagccccgcc caatgcttta cccaacgtac cggtaatgat
    17041 gtctacacgc cccatcacat cgcagtattc atgggaacca cgaccgtttt caccgacaaa
    17101 accgaccgcg tgggagtcgt ctaccatcac cagggcatcg tatttatctg ccagatcgca
    17161 aacgcccttc agattggcaa tcacgccgtc catcgagaac acaccatcgg tggcaatcag
    17221 cacatgacgc gcaccggctt cacgcgcttc tttcagacga gcttccagct cctgcatatc
    17281 gttgttggca tagcgatagc gtttagcttt acacagacgc acaccatcaa taatagacgc
    17341 gtggttcagt gcgtcggaga taatggcgtc ttccgcgccc aacagcgttt caaacaggcc
    17401 accgttagca tcaaagcagg aagagtagag aatcgcatct tccatcccca ggaaggccgc
    17461 cagtttttgt tcaagctctt tatgactgtc ctgagtgccg caaataaaac gcaccgaagc
    17521 catgccgaaa ccgtgagaat ccattcccgc ctttgccgcc gcaatcagat ccggatgatt
    17581 cgccagtccg agatagttat tggcacaaaa gttaatgacg tggcttccat cagccacagt
    17641 gatatctgct tgctgcgcag acgtaataat gcgctcttct ttaaacaacc cttccgcccg
    17701 tgcggtttcc agatcgttgg ttaactgctg ataaaattct ccacgcattg cgattctcca
    17761 gacagggcaa attccagcac atattaccca aacttatagg tcgcgacgag atgacgcgtt
    17821 aacacttctg caaaattcag gataaataac gtccagcccc ctcacttttg gtgaatggct
    17881 gaagccaacg tcatgtagtg atatgataga agtattcgtg tctgagattg tctctgactc
    17941 cataattcga aggttacagc tatgatcatc gttaccggcg gcgcgggctt tatcggcagc
    18001 aacatcgtta aagccctgaa tgataaaggc atcaccgata ttctggtggt ggacaacctg
    18061 aaagacggca ccaagtttgt caacctggtg gatctggata tcgcggacta tatggataag
    18121 gaagacttcc tgatccagat tatggctggc gaagagttcg gcgatgtcga agcgattttc
    18181 cacgaaggcg cgtgctcttc caccaccgag tgggacggca agtatatgat ggataacaac
    18241 tatcaatact ccaaagagct gctgcactac tgtctggagc gcgaaatccc gttcctgtat
    18301 gcctcttccg cagccactta cggtggacgc acctccgact ttattgaatc ccgcgaatat
    18361 gaaaaaccgt tgaatgtcta cggttactca aaattcctgt ttgatgaata tgttcgccaa
    18421 atcctgcctg aagcgaactc gcagattgtt ggcttccgtt atttcaacgt ttatggaccg
    18481 cgtgaaggcc ataaaggcag catggcgagc gtcgctttcc atctcaacac ccagcttaat
    18541 aacggtgaat caccgaagct gttcgaaggt agcgagaact ttaaacgcga cttcgtctat
    18601 gtgggcgacg tggcagatgt aaacctgtgg ttcctggaaa atggcgtttc cggcatcttc
    18661 aacctcggta ctggtcgtgc ggaatccttc caggctgtag cagatgctac gcttgcttat
    18721 cacaagaaag gccagatcga atacattccg ttcccggata aactgaaagg ccgctatcag
    18781 gcgttcacgc aggcagacct gacgaatctg cgcgcggcgg gttatgacaa accgttcaaa
    18841 accgttgccg aaggcgtaac ggaatacatg gcctggctga atcgcgacgc ataagagctc
    18901 tgcatgaaaa tactggtgat cggcccgtct tgggttggcg acatgatgat gtcgcaaagt
    18961 ctctatcgca cgctccaggc gcgctatccc caggcgataa tcgacgtgat ggcaccggca
    19021 tggtgccgtc cattattatc gcggatgccg gaagttaacg aagctattcc tatgcctctc
    19081 ggtcacggag cgctggaaat cggcgaacgc cgcaaactgg gtcatagtct gcgtgaaaag
    19141 cgctacgacc gcgcctacgt cttacccaac tccttcaagt ccgcattagt gcctttcttc
    19201 gcgggtattc ctcatcgcac cggctggcgc ggcgagatgc gctacggttt acttaacgat
    19261 gtacgcgtgc tcaataaaga agcctggccg ctaatggtgg aacgctatgt cgcgctggcc
    19321 tatgacaaag gcattatgcg tacagcacaa gatctgccgc agccattgtt atggccgcag
    19381 ttgcaggtga gcgaaggtga aaaatcatat acctgtaatc aattttcgct ttcatcagaa
    19441 cgtccgatga ttggcttttg cccgggtgcg gagtttggtc cggcaaaacg ctggccacac
    19501 taccactatg cggagctggc aaagcagctg attgatgaag gttatcaggt ggttctgttt
    19561 ggctcggcga aagatcatga agcgggcaat gagattcttg ccgctttgaa tactgagcag
    19621 caggcatggt gtcgtaacct ggcgggggaa acacagcttg atcaagcggt tatcctgatt
    19681 gcagcctgta aagccattgt cactaacgat tctggcctga tgcacgttgc ggcggcgctc
    19741 aatcgtccgc tggttgccct gtatggtccg agtagcccag acttcacacc gccgctatcc
    19801 cataaagcgc gcgtgatccg cctgattacc ggctatcaca aagtgcgtaa aggtgacgct
    19861 gcggagggtt atcaccagag cttgatcgac attactcccc agcgcgtact ggaagaactc
    19921 aacgcgctat tgttacaaga ggaagcctga cggatgcggg ttttgatcgt taaaacatcg
    19981 tcgatgggcg atgttctcca tacgttgccc gcactcactg atgcccagca ggcaatccca
    20041 gggattaagt ttgactgggt ggtggaagaa gggttcgcac agattccttc ctggcacgcc
    20101 gccgttgagc gagttattcc tgtggcaata cgtcgctggc gtaaagcctg gttctcggcc
    20161 cccataaaag ctgaacgcaa agcgtttcgt gaagcgctac aagcagagaa ctatgacgca
    20221 gttatcgatg ctcaggggct ggtaaaaagc gcggcgctgg tgacgcgtct ggcgcatggc
    20281 gtaaagcatg gcatggactg gcaaaccgct cgcgaacctt tagccagcct gttttacaat
    20341 cgtaagcatc atattgcgaa acagcagcac gccgtagaac gcacccgcga actgtttgcc
    20401 aaaagtttgg gctatagcaa accgcaaacc cagggcgatt atgctatcgc acagcatttc
    20461 ctgacgaacc ggcctacaga tgctggcgaa tatgccgtat ttcttcatgc gacgacccgt
    20521 gatgataaac actggccgga agaacactgg cgagaattga ttggtttact ggctgattca
    20581 ggaatacgga ttaaacttcc gtggggcgcg ccgcatgagg aagaacgggc gaaacgactg
    20641 gcggaaggat ttgcttatgt tgaagtattg ccgaagatga gtctggaagg cgttgcccgc
    20701 gtgctggccg gggctaaatt tgtagtgtcg gtggatacgg ggttaagcca tttaacggcg
    20761 gcactggata gacccaatat cacggtttat ggaccaaccg atcctggatt aattggtggg
    20821 tatgggaaga atcagatggt ttgtagggct ccgctaaaga gtttaaataa tttagaagca
    20881 gcggctgttt ataaaaaaat cacattgatt taataaatag taagtgggca ttatacccac
    20941 ttacttagtc aacgctttta ttattgtggt tcttttttac tcaaaaacga tatagacagg
    21001 aagaggcaca caatccacga tgccggtatt ggtttagcat gtgtaatgac atcactaatg
    21061 ccaaataaca taatagaagc agggaaaacc aagagtatat attttttctc ccggatacag
    21121 taatagatca ttgcaacata gaacataata agaacaagaa gaccaatttt tcctttcgtg
    21181 gaaagagatt ccacaatttc gttatgcata tgtacatcaa ggaataataa agctccacta
    21241 taaatattat tttctgcact taatgctttt atcttttcag cacgctgctc aagagattgc
    21301 caattaaaac catcaggact tcctttaatt cctgcattaa ccattgcaaa acgtgctccg
    21361 accgaggatt gactgttatt ttttgtagca tatgaaataa catcagcttt taatgaatta
    21421 attcgcctat caatttcctt attaaatatc aaaccacaag caagtagcaa tataaaaaca
    21481 ccactcaatc ctttaaataa aaacactttt tgatcacgat gctgaagaaa taatatgacc
    21541 ataatcataa gtgggaatgt gaaaattgcc gcacgcgttc ctgtcatcat tactgctgca
    21601 aagcttaaag caaagttagc ataaaataga aaccatttat atttcgattg cattttgatg
    21661 aatacaattg aagaatataa agtagtgaat gtaatcacat aagccgcaat agtcgctgcc
    21721 cccatctgac caatattccc attcatggcg gagaggggaa tgcggtctgc atgcaaatat
    21781 atcccttgat aatatgctct acatagcatg attatttgaa ctaagatagc tgaaataaaa
    21841 tgtagttttt cattttgcct gaatttattt ttacttagta ataaaaatgt caacgagcta
    21901 aatactaata gttttccaga ctcaaggtag cc
//
LOCUS       DADXDL010000079        21841 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.079, whole genome shotgun sequence.
ACCESSION   DADXDL010000079 DADXDL010000000
VERSION     DADXDL010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21841
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.079"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            319..990
                     /locus_tag="IRB70_003526"
     CDS             319..990
                     /locus_tag="IRB70_003526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIG-L family deacetylase"
                     /protein_id="HBC0633392.1"
                     /translation="MDKVLDSALLSSANKRKGILAIGAHPDDIELGCGASLARLAQKG
                     IYIAAVVMTTGNSGTDGIIDRHEESRNALKILGCHQTIHLNFADTRAHLQLNDMISAL
                     EDIIKNQIPSDVEIIRVYTMHDADRHQDHLAVYQASMVACRTIPQILGYETPSTWLSF
                     MPQVFESVKEEYFTVKLAALKKHKSQERRDYMRHDRLRAVAQFRGQQVNSDLGEGFVI
                     HKMIL"
     gene            1000..2196
                     /locus_tag="IRB70_003527"
     CDS             1000..2196
                     /locus_tag="IRB70_003527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBC0633393.1"
                     /translation="MKTWIFICMAVAILLWFLSTLRRKPSQKKGCIDAIIPAYNEGPC
                     LAQSLDNLLRNPYFCRVICVNDGSTDNTEAVMAEVKRKWGDRFVAVTQKNTGKGGALM
                     NGLNYATCDQVFLSDADTYVPPDQDGMGYMLAEIERGADAVGGIPSTALKGAGLLPHI
                     RATVKLPMIVMKRTLQQLLGGAPFIISGACGMFRTDVLRKFGFSDRTKVEDLDLTWTL
                     VANGYRIRQANRCIVYPQECNSPREEWRRWRRWIVGYAVCMRLHKRLLFSRFGIFSIF
                     PMLLVVLYGVGIYLTTWFNEFITTGPHGVVLAMFPLIWVGVVCVIGAFSAWFHRCWLL
                     VPLAPLSVVYVLLAYAIWIIYGLIAFFTGREPQRDKPTRYSALVEASTAYSQPSVTGT
                     EKLSEA"
     gene            2174..2755
                     /locus_tag="IRB70_003528"
     CDS             2174..2755
                     /locus_tag="IRB70_003528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012602184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBC0633394.1"
                     /translation="MKNFLKLNVKEKNIQIADQVIIDETAGEVVIGANTRICHGAVIQ
                     GPVVIGANCLIGNYAFIRPGTIISNGVKIGFATEIKNAVIEAEATIGPQCFIADSVVA
                     NQAYLGAQVRTSNHRLDEQPVSVRTPEGIIATGCDKLGCYIGQRSRLGVQVIILPGRI
                     ISPNTQLGPRVIVERNLPTGTYSLRQELIRTGD"
     gene            2757..3530
                     /locus_tag="IRB70_003529"
     CDS             2757..3530
                     /locus_tag="IRB70_003529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiO family outer membrane beta-barrel protein"
                     /protein_id="HBC0633395.1"
                     /translation="MIKRTLLAAAIFSTLPAYAGLTSITAGYDFTDYSGDHGNRNLAY
                     AELVAKVENATLLFNLSQGRRDYETEHFNATRGQGAVWYKWNNWLTTRTGIAFADNTP
                     VFARQDFRQDINLALLPKTLFTTGYRYTKYYDDVEVDAWQGGVSLYTGPVISSYRYTH
                     YDSSDAGGSYSNMISVRLNDPRGTGYTQLWLSRGTGAYTYDWTPETRYGSMKSVSLQR
                     IQPLTEQLNLGLTAGKVWYDTPTDDYNGLQLAAHLTWKF"
     gene            3715..3990
                     /gene="frmR"
                     /locus_tag="IRB70_003530"
     CDS             3715..3990
                     /gene="frmR"
                     /locus_tag="IRB70_003530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414891.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formaldehyde-responsive transcriptional
                     repressor FrmR"
                     /protein_id="HBC0633396.1"
                     /translation="MPSTPEEKKKVLTRVRRIRGQIDALERSLEGDAECRAILQQIAA
                     VRGAANGLMAEVLESHIRETFDRNDCYSREVSQSVDDTIELVRAYLK"
     gene            4025..5134
                     /gene="frmA"
                     /locus_tag="IRB70_003531"
     CDS             4025..5134
                     /gene="frmA"
                     /locus_tag="IRB70_003531"
                     /EC_number="1.1.1.284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-(hydroxymethyl)glutathione dehydrogenase"
                     /protein_id="HBC0633397.1"
                     /translation="MKSRAAVAFAPGKPLEIVEIDVAPPKKGEVLIKVTHTGVCHTDA
                     FTLSGDDPEGVFPVVLGHEGAGVVVEVGEGVTSVKPGDHVIPLYTAECGECEFCRSGK
                     TNLCVAVRETQGKGLMPDGTTRFSYNGQPLYHYMGCSTFSEYTVVAEVSLAKINPEAN
                     HEHVCLLGCGVTTGIGAVHNTAKVQPGDSVAVFGLGAIGLAVVQGARQAKAGRIIAID
                     TNPKKFDLARRFGATDCINPNDYDKPIKDVLLDINKWGIDHTFECIGNVNVMRAALES
                     AHRGWGQSVIIGVAGSGQEISTRPFQLVTGRVWKGSAFGGVKGRSQLPGMVEDAMKGD
                     IDLEPFVTHTMSLDEINDAFDLMHEGKSIRTVIRY"
     gene            5226..6059
                     /gene="fghA"
                     /locus_tag="IRB70_003532"
     CDS             5226..6059
                     /gene="fghA"
                     /locus_tag="IRB70_003532"
                     /EC_number="3.1.2.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-formylglutathione hydrolase"
                     /protein_id="HBC0633398.1"
                     /translation="MELIEKHASFGGWQNVYRHYSQSLKCEMNVGVYLPPKAGNEKLP
                     VLYWLSGLTCNEQNFITKSGMQRYAAEHNIIVVAPDTSPRGSHVADADRYDLGQGAGF
                     YLNATQAPWNEHFKMYDYIRSELPDLVLKHFPATARKSISGHSMGGLGALVLALRNPD
                     EYASVSAFSPIVSPSQVPWGQQAFAAYLGENKEAWLDYDPVSLISQGQRVAEIMVDQG
                     LSDDFYAEQLRTSNLEKICQEMNIKTLIRYHEGYDHSYYFVSSFIGEHIAYHANKLNM
                     R"
     gene            complement(6184..6723)
                     /locus_tag="IRB70_003533"
     CDS             complement(6184..6723)
                     /locus_tag="IRB70_003533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414888.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2058 domain-containing protein"
                     /protein_id="HBC0633399.1"
                     /translation="MAKLTLQEQLLKAGLVTSKKAAKVERTAKKSRVQAREARAAVEE
                     NKKAQLERDKQLSEQQKQAALAKEYKAQVKQLIEMNRITIANGDIGFNFTDGNLIKKI
                     FVDKLTQTQLINGRLAIARLQIDNNSEGEYAIIPASVADKIAQRDASSIVLHSALSAE
                     EQDEDDPYADFKVPDDLMW"
     gene            complement(6825..8036)
                     /gene="mhpT"
                     /locus_tag="IRB70_003534"
     CDS             complement(6825..8036)
                     /gene="mhpT"
                     /locus_tag="IRB70_003534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-(3-hydroxy-phenyl)propionate transporter MhpT"
                     /protein_id="HBC0633400.1"
                     /translation="MSTRIPSSSSSRLMLTIGLCFLVALMEGLDLQATGIAAGGIAQA
                     FALDKMQMGWIFSAGILGLLPGALVGGMLADRYGRKRILISSVALFGLFSLATAIAWD
                     FPSLVFARLMTGVGLGAALPNLIALTSEAAGPRFRGTAVSLMYCGVPIGAALAATLGF
                     AGANLAWQMVFWVGGVVPLILVPLLMRWLPESAVFAGEKQAAPPLRALFAPETATATL
                     LLWLCYFFTLLVVYMLINWLPLLLVEQGLQPSQAAGVMFALQMGAASGTLMLGALMDK
                     LRPVTMSLLIYSGMLASLLALGTVSSFNGMLLAGFVAGLFATGGQSVLYALAPLFYSS
                     QIRATGVGTAVAVGRLGAMSGPLLAGKMLALGTGTVGVMAASAPGILVAGLAVFILMS
                     RRSRMQPCADA"
     gene            complement(8216..9229)
                     /gene="dmpG"
                     /locus_tag="IRB70_003535"
     CDS             complement(8216..9229)
                     /gene="dmpG"
                     /locus_tag="IRB70_003535"
                     /EC_number="4.1.3.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-2-oxovalerate aldolase"
                     /protein_id="HBC0633401.1"
                     /translation="MNDKKLYISDVTLRDGMHAIRHQYSLENVRQVAKALDDARVDSI
                     EVAHGDGLQGSSFNYGFGAHSDLEWIEAAADVVKHAKIATLLLPGIGTIHDLKNAWQA
                     GARVVRVATHCTEADVSAQHIQYARELGMDTVGFLMMSHMTTPENLAKQAKLMEGYGA
                     TCIYVVDSGGAMNMSDIRDRFRALKAVLKPETQTGIHAHHNLSLGVANSIAAVEEGCD
                     RIDASLAGMGAGAGNAPLEVFIAAADKLGWQHGTDLYALMDAADDLVRPLQDRPVRVD
                     RETLALGYAGVYSSFLRHCETAAARYGLSAVDILVELGKRRMVGGQEDMIVDVALDLR
                     NNK"
     gene            complement(9226..10176)
                     /gene="mhpF"
                     /locus_tag="IRB70_003536"
     CDS             complement(9226..10176)
                     /gene="mhpF"
                     /locus_tag="IRB70_003536"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetaldehyde dehydrogenase"
                     /protein_id="HBC0633402.1"
                     /translation="MSKRKVAIIGSGNIGTDLMIKILRHGQHLEMAVMVGIDPQSDGL
                     ARARRMGVATTHEGVIGLMNMPEFADIDIVFDATSAGAHVKNDAALREAKPDIRLIDL
                     TPAAIGPYCVPVVNLEENVAQLNVNMVTCGGQATIPMVAAVSRVARVHYAEIIASIAS
                     KSAGPGTRANIDEFTETTSRAIEVVGGAAKGKAIIVLNPAEPPLMMRDTVYVLSDEAS
                     QDDIEASINEMAEAVQAYVPGYRLKQRVQFEVIPQDKPVNLPGVGQFSGLKTAVWLEV
                     EGAAHYLPAYAGNLDIMTSSALATAEKMAQSLARKAGEAA"
     gene            complement(10173..10982)
                     /gene="mhpD"
                     /locus_tag="IRB70_003537"
     CDS             complement(10173..10982)
                     /gene="mhpD"
                     /locus_tag="IRB70_003537"
                     /EC_number="4.2.1.80"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414884.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-4-pentenoate hydratase"
                     /protein_id="HBC0633403.1"
                     /translation="MTKHTLEQLAADLRRAAEQGEAIAPLRDLIGIDNAEAAYAIQHI
                     NVQHDVAQGRRVVGRKVGLTHPKVQQQLGVDQPDFGTLFADMCYGDNETIPFSRVLQP
                     RIEAEIALVLNRDLPATDITFDELYNAIEWVLPALEVVGSRIRDWSIQFVDTVADNAS
                     CGVYVIGGPAQRPAGFDLKNCAMKMTRNNEEVSSGRGSECLGHPLNAAVWLARKMASL
                     GEPLRAGDIILTGALGPMVAVNAGDRFEAHIEGIGSVAATFSSAAPKGSLS"
     gene            complement(10992..11858)
                     /gene="mhpC"
                     /locus_tag="IRB70_003538"
     CDS             complement(10992..11858)
                     /gene="mhpC"
                     /locus_tag="IRB70_003538"
                     /EC_number="3.7.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414883.5"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-6-oxonona-2,4-dienedioate hydrolase"
                     /protein_id="HBC0633404.1"
                     /translation="MSYQPQTEAATSRFLNVEEAGKTLRIHFNDCGQGDETVVLLHGS
                     GPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSIVNSGSRSDLNARILKSVVDQ
                     LDIAKIHLLGNSMGGHSSVAFTLNWPERVGKLVLMGGGTGGMSLFTPMPTEGIKRLNQ
                     LYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSRRDHLENFVKSLEANPKQFP
                     DFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLSGIAGSELHIFRDCGHWAQWEHADA
                     FNQLVLNFLARP"
     gene            complement(11876..12820)
                     /gene="mhpB"
                     /locus_tag="IRB70_003539"
     CDS             complement(11876..12820)
                     /gene="mhpB"
                     /locus_tag="IRB70_003539"
                     /EC_number="1.13.11.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-carboxyethylcatechol 2,3-dioxygenase"
                     /protein_id="HBC0633405.1"
                     /translation="MHAYLHCLSHSPLVGYVDPAQEVLDEVNGVIASARERIAAFSPE
                     LVVLFAPDHYNGFFYDVMPPFCLGVGATAIGDFGSAAGELPVPVELAEACAHAVMKSG
                     IDLAVSYCMQVDHGFAQPLEFLLGGLDKVPVLPMFINGVATPLPGFQRTRMLGEAIGR
                     FTSTLNKRVLFLGSGGLSHQPPVPELAKADAHMRDRLLGSGKDLPASERELRQQRVIS
                     AAEKFVEDQRTLHPLNPIWDNQFMTLLEQGRIQELDAFSNEELSAIAGKSTHEIKTWV
                     AAFAAISAFGNWRSEGRYYRPIPEWIAGFGSLSARTEN"
     gene            complement(12822..14486)
                     /locus_tag="IRB70_003540"
     CDS             complement(12822..14486)
                     /locus_tag="IRB70_003540"
                     /EC_number="1.14.13.127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     3-(3-hydroxy-phenyl)propionate/3-hydroxycinnamic acid
                     hydroxylase"
                     /protein_id="HBC0633406.1"
                     /translation="MAIQHPDIQPAVNHSVQVAIAGAGPVGLMMANYLGQMGIDVLVV
                     EKLDKLIDYPRAIGIDDEALRTMQSVGLVDNVLPHTTPWHAMRFLTPKGRCFADIQPM
                     TDEFGWPRRNAFIQPQVDAVMLEGLSRFPNVRCLFSRELEAFSQQDDEVTVHLKTAEG
                     QRETVKAQWLVACDGGASFVRRTLNVPFEGKTAPNQWIVVDIANDPLSTPHIYLCCDP
                     VRPYVSAALPHAVRRFEFMVMPGETEEQLREPQNMRKLLSKVLPNPDNVELIRQRVYT
                     HNARLAQRFRIDRVLLAGDAAHIMPVWQGQGYNSGMRDAFNLAWKLALVIQGKARDAL
                     LDTYQQERRDHAKAMIDLSVTAGNVLAPPKRWQGTLRDGVSWLLNYLPPVKRYFLEMR
                     FKPMPQYYGGALVREGEAKHSPVGKMFIQPKVTLENGDVTLLDNAIGANFAVIGWGCN
                     PLWGMSDEQIQQWRALGTRFIQVVPEVQIHTAQDNHDGVLRVGDTQGRLRSWFAQHNA
                     SLVVMRPDRFVAATAIPQTLGKTLNKLASVMTLTRPDADVSVEKVA"
     gene            14677..15510
                     /gene="mhpR"
                     /locus_tag="IRB70_003541"
     CDS             14677..15510
                     /gene="mhpR"
                     /locus_tag="IRB70_003541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414880.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator MhpR"
                     /protein_id="HBC0633407.1"
                     /translation="MQNNEQTEYKTVRGLTRGLMLLNMLNKLDGGASVGLLAELSGLH
                     RTTVRRLLETLLEEGYVRRSTSDDSFRLTIKVRQLSEGFRDEQWISALAAPLLGDLLR
                     EVVWPTDVSTLDVDAMVVRETTHRFSRLSFHRAMVGRRLPLLKTASGLTWLAFCPEQE
                     RKELIEMLASRPGDDYQLAREPLKLEAILARARKEGYGQNYRGWDQEEKIASIAVPLR
                     SEQRVIGCLNLVYMASAMTIEQAAEKHLPALQRVAKQIEEGVESQAILVAGRRSGVHL
                     R"
     gene            15587..16669
                     /gene="lacI"
                     /locus_tag="IRB70_003542"
     CDS             15587..16669
                     /gene="lacI"
                     /locus_tag="IRB70_003542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414879.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor LacI"
                     /protein_id="HBC0633408.1"
                     /translation="MKPVTLYDVAEYAGVSYQTVSRVVNQASHVSAKTREKVEAAMAE
                     LNYIPNRVAQQLAGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERS
                     GVEACKAAVHNLLAQRVSGLIINYPLDDQDAIAVEAACANVPALFLDVSDQTPINSII
                     FSHEDGTRLGVEHLVALGHQQIALLAGPLSSVSARLRLAGWHKYLTRNQIQPIAEREG
                     DWSAMSGFQQTMQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDT
                     EDSSCYIPPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLLPVSLVKRKTTLPSNT
                     QTASPQALADSLMQLARQISRLESGQ"
     gene            16792..19866
                     /gene="lacZ"
                     /locus_tag="IRB70_003543"
     CDS             16792..19866
                     /gene="lacZ"
                     /locus_tag="IRB70_003543"
                     /EC_number="3.2.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HBC0633409.1"
                     /translation="MTMITDSLAVVLQRRDWENPGVTQLNRLAAHPPFASWRNSEEAR
                     TDRPSQQLRSLNGEWRFAWFPAPEAVPESWLECDLPEADTVVVPSNWQMHGYDAPIYT
                     NVTYPITVNPPFVPAENPTGCYSLTFNVDESWLQEGQTRIIFDGVNSAFHLWCNGRWV
                     GYGQDSRLPSEFDLSAFLRAGENRLAVMVLRWSDGSYLEDQDMWRMSGIFRDVSLLHK
                     PTTQISDFHVATRFNDDFSRAVLEANVQMYGELRDELRVTVSLWQGETQVASGTAPFG
                     GEIIDERGGYADRVTLRLNVENPKLWSAEIPNLYRAVVELHTADGTLIEAEACDVGFR
                     EVRIENGLLLLNGKPLLIRGVNRHEHHPLHGQVMDEQTMVQDILLMKQNNFNAVRCSH
                     YPNHPLWYTLCDRFGLYVVDEANIETHGMVPMNRLTDDPRWLPAMSERVTRMVQRDRN
                     HPSVIIWSLGNESGHGANHDALYRWIKSVDPSRPVQYEGGGADTTATDIICPMYARVD
                     EDQPFPAVPKWSIKKWLSLPGETRPLILCEYAHAMGNSLGGFAKYWQAFRQYPRLQGG
                     FVWDWVDQSLIKYDENGNPWSAYGGDFGDTPNDRQFCMNGLVFADRTPHPALTEAKHQ
                     QQFFQFRLSGRTIEVTSEYLFRHSDNELLHWSVALDGKPLASGEVPLDVAPQDKQVIE
                     LPELPQPESTGQLWLTVHVVQPNATAWSEARHISAWQQWRLAENLSVTLPSAPHAIPQ
                     LTTSETDFCIELGNKRWQFNRQSGFLSQMWIGDEKQLLTPLRDQFTRAPLDNDIGVSE
                     ATRIDPNAWVERWKTAGHYQAKAALLQCTADTLADAVLITTAHAWQHQGKTLFISRKT
                     YRIDGSGQMAITVDVEVASDAPHPARIGLTCQLAQVAERVNWLGLGPQENYPDRLTAA
                     CFDRWDLPLSDMYTPYVFPSENGLRCGTRELNYGPHQWRGDFQFNISRYSQQQLMETS
                     HRHLLHAEEGTWLNIDGFHMGIGGDDSWSPSVSAEFQLSAGRYHYQLVWCQK"
     gene            19918..21171
                     /gene="lacY"
                     /locus_tag="IRB70_003544"
     CDS             19918..21171
                     /gene="lacY"
                     /locus_tag="IRB70_003544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactose permease"
                     /protein_id="HBC0633410.1"
                     /translation="MYYLKNTNFWMFGLFFFFYFFIMGAYFPFFPIWLHDINHISKSD
                     TGIIFAAISLFSLLFQPLFGLLSDKLGLRKYLLWIITGMLVMFAPFFIFIFGPLLQYN
                     ILVGSIVGGIYLGFCFNAGAPAVEAFIEKVSRRSNFEFGRARMFGCVGWALCASIVGI
                     MFTINNQFVFWLGSGCALILAVLLFFAKTDAPSSATVANAVGANHSAFSLKLALELFR
                     QPKLWFLSLYVIGVSCTYDVFDQQFANFFTSFFATGEQGTRVFGYVTTMGELLNASIM
                     FFAPLIINRIGGKNALLLAGTIMSVRIIGSSFATSALEVVILKTLHMFEVPFLLVGCF
                     KYITSQFEVRFSATIYLVCFCFFKQLAMIFMSVLAGNMYESIGFQGAYLVLGLVALGF
                     TLISVFTLSGPGPLSLLRRQVNEVA"
     gene            21237..>21841
                     /gene="lacA"
                     /locus_tag="IRB70_003545"
     CDS             21237..>21841
                     /gene="lacA"
                     /locus_tag="IRB70_003545"
                     /EC_number="2.3.1.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactoside O-acetyltransferase"
                     /protein_id="HBC0633411.1"
                     /translation="MNMPMTERIKAGKLFTDMCEGLPEKRLRGKTLMYEFNHSHPSEV
                     EKRESLIKEMFATVGENAWIEPPVYFSYGSNIHIGRNFYANFNLTIVDDYTVTIGDNV
                     LIAPNVTLSVTGHPVHHELRKNGEMYSFPITIGNNVWIGSHVVINPGVTIGDNAVIGA
                     GSVVTKDIPPNVVAAGVPCRVIREINDRDKHYYYKDYKVEPS"
BASE COUNT         5186 a         5873 c         5611 g         5171 t
ORIGIN      
        1 gcatattaca ttcacataat gtatataaac aatacttgtt cacagaacat attttttaaa
       61 tgcaattaat tgacaaacta aatcacatct aaatacaatg tataaaacaa aataactata
      121 cataccaaac atacaaacac ttaacatatg aattgcataa aaacattaac cagtcgcccc
      181 cccggatctg aaagccctgg cttttcaatt attagcaaca tttaacactt ataaattagc
      241 atctggctgc gccagagatt acgtctctga gtgcatcgtt gtgcttgtag tataataaat
      301 aaaatggagt gtcattaagt ggataaggtt ttagattcag ccctcctttc ttcggcaaat
      361 aaaagaaagg gtatccttgc tattggcgca catcctgacg atatagaatt aggctgtggc
      421 gcatcgcttg ctcgtcttgc gcaaaaagga atttatatcg cagccgtggt gatgactacc
      481 ggcaactctg gcacagatgg aataatcgat cgccatgaag aatcgcgcaa cgccctaaag
      541 atattagggt gccaccaaac tattcatctt aattttgctg acacccgcgc tcatttacag
      601 ctcaatgata tgatttccgc cctggaagac atcattaaaa atcaaattcc gtctgatgta
      661 gaaatcattc gtgtatacac catgcatgat gctgaccgcc atcaggatca tcttgcagtc
      721 tatcaagcct caatggttgc ctgccgaact attccacaaa ttctcggcta cgaaaccccg
      781 agtacctggc tttcatttat gcctcaggtt tttgaatccg ttaaagaaga atatttcaca
      841 gtcaaacttg ctgcattaaa aaaacataaa agccaggaac gacgcgatta tatgcgtcat
      901 gatcgcctgc gtgcagttgc acaatttcgc gggcaacagg tcaatagcga tctgggtgaa
      961 ggctttgtaa ttcataaaat gattctttga gcaaattgca tgaaaacctg gatatttatc
     1021 tgtatggccg tagcaatatt gctatggttc ctgagtacgt taaggcgtaa gcccagccaa
     1081 aaaaaaggct gtattgacgc cattatacct gcttataacg aaggcccgtg tctggcgcag
     1141 tcactggata atctgctgcg taacccttat ttttgccggg taatttgcgt taacgacggc
     1201 tccacggaca ataccgaagc ggtcatggcg gaagtcaaac gcaaatgggg cgaccgcttt
     1261 gttgccgtca cgcaaaaaaa taccggtaaa ggtggtgcgc tgatgaatgg cctcaattac
     1321 gccacctgcg accaggtttt tttaagtgat gccgacacct atgttccgcc cgatcaagac
     1381 ggaatgggct atatgctggc agaaattgag cgcggtgctg atgccgtagg cggcattccc
     1441 tctactgcgt tgaaaggcgc ggggctgtta ccgcacatcc gcgcgaccgt aaagttgccg
     1501 atgattgtta tgaagcgcac gctacagcag ctcctgggcg gcgcaccgtt tattatcagc
     1561 ggtgcctgcg ggatgttccg tactgatgta ttgcgtaagt tcggtttctc tgatcgtact
     1621 aaagtcgaag accttgatct cacctggaca ttggtggcaa acggctatcg tattcggcag
     1681 gcgaatcgct gcatcgtata cccacaggaa tgcaacagcc cgcgtgagga atggcgtcgc
     1741 tggcggcgtt ggattgtggg ctacgcggtc tgtatgcgcc tgcataaaag acttttattt
     1801 agccgcttcg gtatcttcag tatatttcct atgctgttgg ttgtgcttta tggcgttggg
     1861 atttatctca ctacctggtt taatgaattc atcaccaccg ggccgcatgg tgtggtgttg
     1921 gcaatgtttc cgcttatctg ggtcggcgta gtttgtgtta ttggtgcttt tagcgcctgg
     1981 tttcatcgtt gctggttgtt ggtgccttta gcgccgcttt ccgttgtgta tgtattatta
     2041 gcttatgcca tctggattat ttatggactt attgcctttt ttactggacg cgaacctcag
     2101 cgcgacaaac ccacccgcta ttccgcactg gtggaagcgt caaccgctta ttcccaacct
     2161 tctgtcacag gaactgaaaa actttctgaa gcttaatgtt aaagagaaaa atattcagat
     2221 tgcagaccag gtaattattg atgaaactgc aggtgaagtt gttatcggcg cgaatacccg
     2281 tatttgtcac ggtgccgtta ttcagggtcc ggtagtgatt ggcgcaaact gcctgatagg
     2341 taattatgcg tttattcgtc ctggcacaat aatcagcaat ggcgtaaaaa ttggtttcgc
     2401 caccgaaatt aaaaatgcgg ttattgaagc ggaagcaacg attggtccgc aatgttttat
     2461 tgccgactcg gtagtcgcaa accaggcata tttgggcgca caagtacgta ccagtaatca
     2521 tcgtctggat gaacagcccg tgtctgttcg aactccagag ggaattatcg ctaccggatg
     2581 cgataaatta ggttgttata tcggacagcg ttcacgcctt ggcgtacaag ttattatttt
     2641 gcctgggcga attatttccc cgaacacgca acttggcccg cgcgtgattg tagaacgtaa
     2701 tttacctacc ggaacttatt cactccgaca agaacttatc cgtacaggag attaaaatga
     2761 taaaacggac gttattagcg gcggccattt ttagcacatt gcccgcttat gccgggttaa
     2821 cttccattac cgcgggctac gattttaccg attattctgg cgatcatggc aatcgtaatt
     2881 tagcgtatgc tgaactggtg gcgaaagttg aaaacgcaac gctgcttttt aatctttccc
     2941 aggggcgtcg tgattatgaa actgaacatt tcaatgccac tcgcggtcag ggtgcggtct
     3001 ggtataaatg gaataactgg ctgacaaccc gaacgggtat tgcctttgcg gataatacgc
     3061 cggtctttgc ccgccaggat tttcgtcagg atattaacct ggccctgttg ccaaaaacgc
     3121 ttttcacgac cggttatcgc tacactaaat attacgatga tgtcgaagtc gatgcctggc
     3181 aaggcggcgt atccctctat actggcccgg tgatctccag ctaccgctat acccattatg
     3241 actccagcga tgcaggtggt agttacagca atatgatttc cgtgcgtctg aatgacccgc
     3301 gcggcactgg ttatacgcaa ctatggctaa gccgcggaac aggcgcttac acctatgact
     3361 ggacgccaga aacacgctac ggcagcatga agagcgtcag tctgcaacgt attcaaccgc
     3421 tgactgagca acttaatctc gggctgacgg caggtaaagt gtggtacgac accccaaccg
     3481 atgattataa cggtctgcaa cttgcagccc atctgacctg gaaattctga ttgcttctgc
     3541 cgcccgctat ccggggcggc cttccctgtc gattaggccc ctctttcctt tttgttatcc
     3601 gactacattc accggataaa ttttattctc cagtgttata tactataggg gggtatgcat
     3661 tgacatatag catacccccc tatagtatat tgcgtgcaga tgatgaggtg cgaaatgccc
     3721 agtactccgg aagagaagaa aaaggtcctt actcgagttc gtcgtattcg ggggcaaatt
     3781 gatgctctgg aacggtcgct ggagggtgat gccgaatgcc gtgccatact ccaacagatc
     3841 gctgccgttc ggggcgcggc taacgggctg atggcagaag tgcttgaaag ccatatccgg
     3901 gaaacgtttg accgaaatga ctgctacagc cgcgaagtca gccaatccgt tgacgacact
     3961 attgaactgg ttcgtgccta tcttaaatag ctgaatctat taccatattg aggaagagcg
     4021 agagatgaaa tcacgtgctg ccgttgcatt tgctcccggt aaaccgctgg aaatcgttga
     4081 aattgacgtt gcaccaccga aaaaaggtga agtgctgatt aaagtcaccc ataccggcgt
     4141 ttgccatacc gacgcattta ccctctccgg cgatgacccg gaaggtgtat tcccggtagt
     4201 tctcggtcac gaaggggccg gcgttgtggt tgaagtcggt gaaggcgtaa ccagcgtcaa
     4261 acctggcgac catgtgatcc cgctttacac cgcagagtgc ggcgagtgtg agttctgtcg
     4321 ttccggcaaa accaacctct gtgttgcagt tcgcgaaacc cagggtaaag gcctgatgcc
     4381 agacggcacc acccgttttt cttacaacgg gcagccgctt tatcactaca tgggatgctc
     4441 tacattcagt gaatacaccg tggtcgcgga agtgtctctg gccaaaatta atccagaagc
     4501 aaaccacgaa cacgtctgcc tgctgggctg tggcgtgacc accggtattg gcgcggtaca
     4561 caacacggct aaagtccagc caggtgattc tgttgccgta tttggtcttg gcgcgattgg
     4621 tctggcagtg gttcagggcg cgcgtcaggc gaaagcggga cggattatcg ctatcgatac
     4681 gaacccgaag aaattcgatc tggcgcgtcg cttcggtgct accgactgca ttaacccgaa
     4741 tgactacgac aaaccgatta aagatgtcct gctggatatc aacaaatggg gtatcgacca
     4801 tacctttgaa tgcatcggta acgtcaacgt gatgcgtgcg gcgctggaaa gtgcgcaccg
     4861 cggctggggt cagtcggtga tcatcggggt agctggttct ggtcaggaaa tctccacccg
     4921 tccattccag ttggtcaccg gtcgcgtatg gaaaggttcc gcgtttggcg gcgtgaaagg
     4981 tcgttcccag ttaccgggta tggttgaaga tgcgatgaaa ggcgatatcg atctggaacc
     5041 gtttgtcacg cataccatga gcctggatga aattaatgac gcctttgacc tgatgcatga
     5101 aggcaaatcc attcgaaccg taattcgtta ctgatttccc gcaggtttac ccgtccagtt
     5161 cagacggggt tcttaatact ctccccgggc agccgtccgg gggattaacc gtgagataat
     5221 gactgatgga actcattgaa aaacatgcca gctttggcgg ctggcaaaat gtgtatcggc
     5281 attattccca atcactgaaa tgtgaaatga atgtcggcgt ctatctccca ccaaaagccg
     5341 ggaatgaaaa attaccggtg ctgtactggc tttcgggcct gacctgcaac gagcagaatt
     5401 tcattactaa atcggggatg caacgttacg cggcggagca caacattatt gttgttgcgc
     5461 cagacaccag tccgcgaggc agtcatgtcg cagatgccga ccgttacgat ctcgggcaag
     5521 gtgccgggtt ctacctgaac gcaacacaag cgccgtggaa tgaacatttc aaaatgtatg
     5581 actacatccg cagcgagcta ccagatttag tgctgaaaca ttttccagca acggcaagaa
     5641 agtcgatatc gggtcattct atgggcgggc tgggcgcgct ggtgctggcg ttacgtaacc
     5701 cagatgaata tgccagcgtc tcggcgtttt cgcccattgt ctccccatcg caagtaccgt
     5761 ggggacagca agcctttgcc gcgtatcttg gtgaaaataa agaagcctgg ttggattacg
     5821 atccggtgag ccttatttca caaggtcaac gcgttgcgga aataatggtt gatcaggggt
     5881 tgagtgatga tttttacgca gaacagctgc ggacttcaaa tcttgaaaag atctgccagg
     5941 agatgaatat caagacgtta atccgttatc acgagggtta tgatcacagc tattattttg
     6001 tctccagttt tattggcgag catattgcgt accacgccaa taaactgaat atgcgttgat
     6061 aatagtgcac gactgccgga tgcggcgtga acgccttatc cgcctacatt tcgcctggaa
     6121 accgtaggca tgataagact cgcaaagcgt cgcatcaggc atctgcacac gatttatcaa
     6181 tgtttaccac atcaaatcat caggcacttt gaagtcagca tacggatcgt cttcatcctg
     6241 ctcttcggcg ctgagcgcgc tgtgcaacac aatactgctg gcatcacgct gagcaatttt
     6301 atcggcaacg ctggcgggaa taatggcgta ttcaccttcg ctattgttat cgatctgcaa
     6361 acgtgcaatc gccagacgac cattaatcaa ctgcgtttgt gtgagcttat cgacaaaaat
     6421 cttcttaatc agattgccat cggtaaagtt aaaaccgata tcgccattgg caatggtgat
     6481 ccggttcatt tcgataagct gcttcacctg agctttatat tctttcgcca acgccgcttg
     6541 tttttgctgc tcactaagct gtttatcacg ctcaagctgt gcctttttat tttcttctac
     6601 cgccgcccga gcttcacgcg cctgaacgcg cgattttttc gccgttctct cgaccttcgc
     6661 cgcttttttg ctggtgacta atcctgcttt gagcaactgc tcttgtaagg taagttttgc
     6721 catctttgtt tccaaacccg ctgaataatt tttagcgagt atacctgtaa acgccgtagg
     6781 tgtattgggg ggaagtccct ttcgcccctg cttaataagg cgcgtcaggc atctgcacac
     6841 ggctgcattc gtgatctccg gctcatcaaa ataaacactg ccaggccggc aacaagaata
     6901 cccggcgcag aagcggccat tacgccaacc gtgccagtgc ctaatgccag cattttcccg
     6961 gccagtaacg gaccgctcat agcccccaga cgccctaccg ccacggctgt tcccacacct
     7021 gttgcgcgga tctgcgaact gtaaaacaac ggtgccaggg catacaaaac gctttgccca
     7081 cctgtcgcaa acaaccccgc gacgaatccc gccagcaaca taccgttaaa tgacgacacc
     7141 gttcccagcg ccagcagcga agctaacatg ccgctataaa tcagtagcga catggttact
     7201 ggacgcagct tatccatcaa tgcgcccaac attaacgtcc cgcttgccgc acccatttgc
     7261 agtgcaaaca tcacccctgc cgcctgcgat ggctgcaatc cttgctccac caaaagcagc
     7321 ggtagccagt tgatcaacat gtagaccacc agcagagtga agaaataaca caaccacagc
     7381 agcagcgtcg cggtagccgt ttctggcgca aataacgcac gcagtggtgg cgcagcctgt
     7441 ttttcgccag cgaacaccgc cgactccggc agccagcgca ttaatagcgg caccagaatc
     7501 aacggcacca caccaccgac ccaaaacacc atttgccatg ctaagtttgc ccccgcgaaa
     7561 cccagcgtcg ccgccagcgc cgcgccaatg ggaacaccgc aatacatcag gctcactgcc
     7621 gtcccacgaa aacgtggccc tgcggcttca gacgtcaggg cgataagatt cggcaacgcc
     7681 gcccccagcc cgacaccggt catcagccgc gcaaagacca gtgaggggaa atcccaggca
     7741 atcgccgttg ccagtgagaa caaaccaaac agcgcaactg agctaattaa aatacgctta
     7801 cgaccataac ggtccgccag cattccgcca accagcgcgc cgggtagcaa accgagtatt
     7861 ccggcgctga atatccagcc catttgcatt ttatcgagtg cgaaagcctg ggcgatgcca
     7921 cccgccgcaa tgccagtcgc ctgaagatcc agtccttcca tcagagcgac caaaaaacaa
     7981 agcccgatgg tcagcatcag gcgggatgaa gatgatgaag ggatacgagt cgacataaga
     8041 tgaacctcgt tgcgagtgca ggtgaatcgc ggctgataca ttgccagccg cgtaatcaga
     8101 accatttaat gactgcctac aggcgaagaa aatgtaggcc gaacaaggcg tttacgccgc
     8161 atccggcagt cgtgctggga tgggcataca aaatgcacgt tctcggcagt catcattatt
     8221 tgttgttgcg cagatccagc gccacatcga cgatcatatc ctcctgaccg ccaaccatcc
     8281 ggcgtttgcc caactcaacg agaatatcca ccgcgcttaa gccataacgc gccgccgccg
     8341 tttcacagtg acgcaggaag ctggagtaaa caccggcgta tcccagcgcc agcgtttcgc
     8401 gatcgactcg taccggacga tcctgcaacg gacgcaccag gtcgtcagcg gcatccatta
     8461 acgcatagag atcggtccca tgctgccaac ccagtttatc cgcggcggca ataaacactt
     8521 ccagcggcgc gttacctgcg cccgcgccca ttcccgcgag actggcatcg attcggtcgc
     8581 agccctcttc caccgccgcg atagagttcg ccacgccaag actcaggtta tggtgagcgt
     8641 gtatgccggt ttgcgtttct ggtttcagca ctgctttcag ggcgcggaaa cggtcacgga
     8701 tatcgctcat gttcatcgca ccgccagaat ccaccacata aatacaggtc gcaccgtagc
     8761 cttccatcag ctttgcctgc tttgcgagat tctccggcgt ggtcatatgg ctcatcatca
     8821 gaaagccaac ggtgtccatt ccgagctcgc gggcatactg aatatgctgg gcggaaacat
     8881 cagcttcggt acagtgcgta gccacacgaa ccacccgcgc gccagcctgc caggcatttt
     8941 tcagatcgtg aatagtgccg attccaggca gcaacaacgt cgcgattttg gcgtgcttca
     9001 ccacatccgc cgccgcttca atccattcaa ggtcgctatg tgcgccgaaa ccatagttaa
     9061 agctggaacc ttgcaaaccg tcgccgtggg ccacttcaat cgaatccacg cgggcatcgt
     9121 ccagtgcttt ggcaacctgg cgaacgtttt ccaatgaata ctgatgacga atggcgtgca
     9181 taccatcacg caacgtgacg tccgagatat aaagtttttt atcgttcatg ccgcttctcc
     9241 tgccttgcgc gccagtgact gggccatttt ttccgctgtc gccagcgcac tggaagtcat
     9301 aatgtcgagg ttgcccgcat aggcaggcag ataatgtgct gcgccttcga cttccagcca
     9361 gacagccgtt ttcagcccgg agaactgccc cacgcccggc aaattaaccg gtttatcctg
     9421 cgggataact tcaaactgca cgcgctgttt caggcgatat cccggtacgt aagcctgcac
     9481 cgcctcagcc atttcattga ttgaggcttc gatatcatct tgtgaagctt cgtcgctcaa
     9541 tacatacacc gtgtcacgca tcatcaacgg tggctctgct gggttaagca cgataattgc
     9601 cttccctttt gccgcgccgc ccaccacttc aatggctcgg gaagtggttt ccgtaaattc
     9661 atcgatattg gcacgcgtgc caggtccggc agatttgctg gcgatagaag cgataatttc
     9721 ggcgtaatga acacgcgcca cgcgtgaaac tgccgccacc attggaatgg tggcctggcc
     9781 gccgcaggtg accatgttga cgttcagttg agcgacgttc tcctcgagat taacgaccgg
     9841 cacgcagtaa gggccgatgg cagcaggcgt caggtcaatt aagcgaatat ccggtttcgc
     9901 ttcgcgcaaa gcggcatcgt ttttcacatg agcaccggcg ctggtcgcat caaatacaat
     9961 gtcgatatca gcaaattcag gcatgttcat cagcccgatc accccttcat gggtggtggc
    10021 aacgcccata cgtctggcac gcgccagacc gtcggactga ggatcaatgc cgaccatcac
    10081 cgccatctcc agatgctgac cgtgacgcaa aattttaatc atcagatcgg tgccaatgtt
    10141 gcctgaaccg ataatggcga ctttacgctt actcatgaca gacttccttt tggggctgcg
    10201 cttgaaaatg tcgcagcaac tgaacctatg ccttcgatat gggcttcaaa acgatcgccc
    10261 gcattcaccg ccaccatcgg acctaatgcc ccggtaagaa tgatatctcc ggcgcgcagc
    10321 ggttcaccca gactggccat tttgcgtgcc agccagacgg cggcattaag cggatgtccc
    10381 aggcattcgc tgccacgccc gctggaaacc tcttcgttat tacgcgtcat cttcatggcg
    10441 cagtttttca ggtcgaaccc cgccggacgt tgcgccggac cgccgatgac atacacccca
    10501 caggaggcgt tatctgccac ggtatcgaca aactgaatcg accagtcgcg aatgcggctc
    10561 cccaccactt ccagcgccgg aagtacccat tcaatggcgt tatacaattc gtcgaaggtg
    10621 atatcggttg cgggtagatc gcggttcaac accagtgcaa tctccgcttc aatgcggggt
    10681 tgcagaacac gggaaaaagg aatggtttca ttatcgccat aacacatgtc ggcaaataat
    10741 gtcccgaaat ccggttgatc aacgcccagt tgttgctgca ctttcggatg cgtcagcccc
    10801 actttacgcc ccaccacgcg acgcccctgc gcgacgtcat gttgcacatt gatgtgctga
    10861 atggcgtagg ccgcttcagc gttatcgata ccaatcagat cgcgcagcgg cgcaatcgct
    10921 tcgccctgct ctgcggcgcg gcgtaaatcc gccgccagtt gctcaagagt atgcttcgtc
    10981 atgaccgttc cttaagggcg tgcgaggaaa ttcagcacca gttgattgaa agcgtcggca
    11041 tgttcccact gcgcccagtg accacagtcg cggaagatat gcagttcaga accggcaatg
    11101 ccggacagca gacgcagacc cgcatccatc ggcacaaagc ggtcgttgcg cccccagaca
    11161 atcagggttt gcgctttgat ttccgccagc cgtgggccaa aatccgggaa ctgtttcgga
    11221 ttggcttcca ggctcttaac gaagttttcc aggtgatcgc ggcgcgacag catattattc
    11281 agacgcgctt caaacagggc gtcggtcaaa tcgctggtat caaaaacgaa gatatccatc
    11341 atcagcttca ggttttcgat agtcggctga cgataaagct gattcagtcg cttaatacct
    11401 tcggttggca tcggcgtaaa caaactcatg ccgcccgtac cgccgcccat cagcaccagt
    11461 ttgccgacgc gctccggcca gttaagggtg aacgccacag aactatggcc acccatcgag
    11521 ttgcccagca ggtggatttt ggcgatatcc agttgatcca ccacgctttt caggattcgt
    11581 gcattaagat ccgatcgcga accactatta acgatcgaat cgctcttgcc ccaacccgga
    11641 caatccagca ggatcacccg atagcccgcc tctaccagcg gatcgatatt gcggctgaag
    11701 ttcgcccagc cagtagcacc cgggccggaa ccatgcagca ggacaacagt ttcgtcgcct
    11761 tgtccgcagt cattaaaatg gatgcgcagc gttttacccg cttcttctac attcagaaaa
    11821 cggctggtgg cggcttcggt ttgtggctga taactcatca tcttctcctg catattcagt
    11881 tctctgttct ggcgcttaac gagccaaatc cggcaatcca ctccgggatt gggcggtaat
    11941 aacgcccttc gctacgccag ttgccaaacg cagaaatagc ggcaaaagcg gcgacccagg
    12001 ttttgatttc atgtgtcgac tttccggcaa tggcggaaag ctcttcgtta ctgaaggcat
    12061 ccagttcctg tatgcgtccc tgctccagca aagtcatgaa ctggttatcc caaatcgggt
    12121 tgagcggatg cagcgttctc tgatcctcaa caaacttctc agcggcgcta atcacccgtt
    12181 gctgacgcaa ttcgcgctca ctggcgggta aatctttccc gctccccaat agacggtcgc
    12241 gcatatgggc atcggctttc gccagttctg gcaccggcgg ctgatgggaa agcccaccgg
    12301 acccaaggaa cagcacgcgt ttattgagag tgctggtgaa acgtccaatg gcttccccca
    12361 acatgcgggt acgctggaaa ccgggcagcg gcgtggcgac accgttgatg aacataggca
    12421 gaactggcac cttatccagc ccaccgagca ggaactccag cggctgggcg aacccgtggt
    12481 ccacctgcat acagtaagaa acggcaagat cgatcccgct cttcatgacg gcatgcgcac
    12541 aggcctccgc cagctccaca ggcacgggca gctcacctgc cgcactgccg aaatcaccaa
    12601 ttgccgtcgc tccaacgcct aaacagaacg gtggcatcac gtcatagaaa aagccgttgt
    12661 agtgatctgg cgcaaacagc accaccagtt caggggagaa agccgcaata cgctcgcggg
    12721 cgctggcaat cacgccattg acctcatcga gtacctcttg tgccgggtcg acatacccca
    12781 ccagcggcga gtgggaaaga cagtgaagat aagcgtgcat atcaggctac cttttcgaca
    12841 gaaacgtcgg catcagggcg ggtcagcgtc atcaccgacg ccagtttatt cagggtcttg
    12901 cccagggttt gcggaatggc ggtggcggca acaaagcgat ccgggcgcat caccaccagc
    12961 gaagcattgt gttgcgcgaa ccagctacgc aggcgacctt gcgtatcccc cacgcgtagt
    13021 acgccgtcgt ggttatcctg tgcggtatga atttgcactt ccggcaccac ctgaatgaag
    13081 cgtgtgccca acgcgcgcca ctgctggatt tgctcgtcgc tcatccccca cagtggattg
    13141 catccccagc caattaccgc gaagttcgcg ccgatcgcgt tatcgagcag cgtcacgtcg
    13201 ccgttttcca gcgtgacttt cggctgaata aacatcttgc cgaccggaga gtgcttcgct
    13261 tcgccctcac gcaccagcgc accgccgtaa tattgcggca tcggcttgaa gcgcatttcg
    13321 aggaagtagc gttttactgg cggcagataa ttcagcagcc aggaaacgcc gtcacgtaac
    13381 gtaccctgcc agcgtttcgg cggagccagc acgttgcccg ccgtcacgga caggtcaatc
    13441 atcgctttgg cgtgatcgcg acgttcttgt tgataggtat cgagcagcgc atcgcgggct
    13501 ttcccctgga taaccaacgc cagtttccat gcgaggttaa aggcgtcgcg cataccactg
    13561 ttatagccct gcccctgcca caccggcatg atgtgcgcgg catcgcccgc cagcagtacg
    13621 cgatcaatac gaaaacgttg cgccagtcgc gcgttgtggg tgtagacacg ctggcgaatc
    13681 aattcaacat tgtccggatt aggcagcact ttgcttaaca gcttgcgcat attttgcggc
    13741 tcacgcagct gttcttcggt ttctcccggc atcaccataa attcaaagcg acgtaccgca
    13801 tgaggcagcg cggcagaaac atacgggcgc accggatcac aacacaaata gatatgcggc
    13861 gtacttaacg gatcgttggc gatatctacc acaatccact gatttggcgc agttttacct
    13921 tcaaacggca cattcagggt gcgacggaca aaacttgccc caccatcaca ggccaccagc
    13981 cactgggctt tgaccgtttc ccgctgccct tctgccgttt tcaggtgcac ggtcacttcg
    14041 tcatcttgct ggctgaaggc ctccagctcg cgggaaaaca ggcagcgcac attcggaaaa
    14101 cgcgacaatc cttccagcat taccgcatcg acctgaggct gaataaaggc gttacggcgc
    14161 ggccagccaa attcatcggt cattggctga atatcagcaa aacagcgacc ttttggggtg
    14221 agaaaacgca tcgcgtgcca cggcgtagtg tgcggcagaa cattatcgac caggccaacc
    14281 gactgcatgg tgcgcagcgc ctcgtcatca ataccaatcg cacgcgggta gtcgatcaac
    14341 ttatcgagtt tctccaccac cagcacgtca atgcccatct ggccgagata gttcgccatc
    14401 atcagcccga ccggaccggc accagcgatc gccacctgaa cgctatggtt aacagcaggc
    14461 tggatgtcag ggtgttgtat tgccatttca gtacctcacg actcggacaa aatgccgttg
    14521 cgcgcacagt acagcgcaac ttattttgtt aaaagcatgt aaatgatttt ttattgtgcg
    14581 ctcagtatag gaagggtgtt ttcggctaca atcaaaacat gcccgaatgt gcaccaggtg
    14641 cacaacgttg ttttaactat ataaatgtca attaatatgc agaacaatga gcagacggaa
    14701 tacaaaaccg tgcgcggctt aacccgcggt ctaatgttat taaatatgtt aaataaactt
    14761 gacggcggtg ccagcgtcgg gctgctggcg gaactcagcg gcctgcatcg caccactgtg
    14821 cggcgactgc tggagacgtt actggaagag ggatatgtcc ggcgcagtac ctccgatgac
    14881 agttttcgtc tgaccatcaa agtgcggcaa ttaagcgaag gatttcgtga cgaacagtgg
    14941 atttctgcac tggcggcccc actgctgggc gatctgttgc gcgaagtggt atggccgaca
    15001 gatgtgtcca cgctggatgt tgatgcaatg gtggtacgcg aaaccaccca tcgtttcagc
    15061 cgcttatctt ttcaccgggc aatggtcggg cgacggttac cgcttctgaa aaccgcctcg
    15121 ggcctgacct ggctggcctt ttgcccggaa caagaacgca aggaattaat cgagatgtta
    15181 gcctcccgcc ccggtgatga ctatcaactg gcacgagaac cgttaaagct ggaagccatt
    15241 ctggcgcgcg cgcgcaaaga ggggtacgga cagaactacc gcggctggga tcaggaggag
    15301 aagatcgcct ctatcgccgt accgctgcgc agtgaacaac gggtgattgg ctgtctgaat
    15361 ctggtgtata tggcgagcgc aatgaccatc gaacaggcag cggaaaagca tcttccggcg
    15421 ctgcaacggg tggcaaaaca gatcgaagaa ggggttgaat cgcaggctat tctggtagcg
    15481 ggaaggcgaa gcggcgtgca tttacgctga aaccatcgaa tggcgcaaaa cctttcgtgg
    15541 tatggcatga tagcgcccgg aagagagtca attcagggtg gtgaatgtga aaccagtaac
    15601 gctatacgat gtcgcagaat atgccggtgt ctcttatcag accgtttccc gcgtggtgaa
    15661 ccaggccagc cacgtttctg cgaaaacgcg ggaaaaagtg gaagcggcga tggcggagct
    15721 gaattacatt cccaaccgcg tggcacaaca actggcgggc aaacagtcgt tgctgattgg
    15781 cgttgccact tccagtctgg ccctgcacgc gccgtcgcaa attgtcgcgg cgattaaatc
    15841 tcgcgctgat caactgggtg ccagcgtggt ggtgtcgatg gtagaacgaa gcggcgtcga
    15901 agcctgtaaa gcggcggtgc acaatcttct cgcgcaacgc gtcagtgggc tgatcattaa
    15961 ctatccgctg gatgaccagg atgccattgc tgtggaagct gcctgcgcta atgttccggc
    16021 tttatttctt gatgtctctg accagacacc catcaacagt attattttct cccatgaaga
    16081 cggtacgcga ctgggcgtgg agcatctggt cgcattgggt caccagcaaa tcgcgctgtt
    16141 agcaggtcca ttaagttctg tctcggcgcg tctgcgtctg gcgggctggc ataaatatct
    16201 cacacgcaat caaattcagc cgatagcgga acgggaaggc gactggagtg ccatgtccgg
    16261 ttttcaacaa accatgcaaa tgctgaatga gggcatcgtc cccactgcga tgctggttgc
    16321 caacgatcag atggcgctgg gcgcaatgcg cgccattacc gagtccgggc tgcgcgttgg
    16381 tgcggatatc tcggtagtgg gatacgacga taccgaagac agctcgtgtt atatcccgcc
    16441 gttaaccacc atcaaacagg attttcgcct gctggggcaa accagcgtgg accgcttgct
    16501 gcaactctct cagggccagg cggtgaaggg caatcagctg ttgcccgtct cactggtgaa
    16561 aagaaaaacc acccttccgt ccaatacgca aaccgcttct ccccaggcgt tggcagattc
    16621 tttaatgcag ctggcgcgac aaatttcccg actggaaagc gggcagtgag cgcaacgcaa
    16681 ttaatgtgag tcagctcact cattaggcac cccaggcttt acattttatg cgtccggctc
    16741 gtatgttgtg tgaaattgtg agcgaataac aatttcacac aggatacagc tatgactatg
    16801 attacggatt cactggccgt cgtattacaa cgtcgtgact gggaaaaccc tggcgttacc
    16861 caacttaatc gcctcgcggc acatccccct ttcgccagct ggcgtaatag cgaagaggcc
    16921 cgcaccgatc gcccttccca acagttgcgc agcctgaatg gcgaatggcg ctttgcctgg
    16981 tttccggcac cagaagcggt gccggaaagc tggctggagt gcgatcttcc tgaggccgat
    17041 actgtcgtcg tcccctcaaa ctggcagatg cacggttacg atgcgcctat ctacaccaac
    17101 gtgacctatc ccattacggt caatccgccg tttgttcccg cggagaatcc gacaggttgt
    17161 tactcgctca catttaatgt tgatgaaagc tggctacagg aaggccagac gcgaattatt
    17221 tttgatggcg ttaactcggc gtttcatctg tggtgcaacg ggcgctgggt cggttacggc
    17281 caggacagcc gtttgccgtc tgaatttgac ctgagcgcat ttttacgcgc cggagaaaac
    17341 cgcctcgcgg tgatggtgct gcgctggagt gacggtagct atctggaaga tcaggatatg
    17401 tggcggatga gcggcatttt ccgtgacgtc tcgttgctgc ataaaccgac cacacaaatc
    17461 agcgatttcc atgttgccac tcgctttaat gatgatttca gccgcgcggt actggaagca
    17521 aacgttcaga tgtacggcga gctgcgcgat gaactgcggg tgacggtttc tttgtggcag
    17581 ggtgaaacgc aggtcgccag cggcaccgcg cctttcggcg gtgaaattat cgatgagcgt
    17641 ggtggttatg ccgatcgcgt cacactacgt ctgaacgtcg aaaacccgaa actgtggagc
    17701 gccgaaatcc cgaatctcta tcgtgcggtg gttgaactgc acaccgccga cggcacgctg
    17761 attgaagcag aagcctgcga tgtcggtttc cgcgaggtgc ggattgaaaa tggtctgctg
    17821 ctgctgaacg gcaagccgtt gctgattcgc ggcgttaacc gtcacgagca tcatcctctg
    17881 catggtcagg tcatggatga gcagacgatg gtgcaggata tcctgctgat gaagcagaac
    17941 aactttaacg ccgtgcgttg ttcgcattat ccgaaccatc cgctgtggta cacgctgtgc
    18001 gaccgcttcg gcttgtacgt ggtggatgaa gccaatattg aaacccacgg catggtgcca
    18061 atgaatcgtc tgaccgatga tccgcgctgg ttacccgcga tgagcgaacg cgtaacgcga
    18121 atggtgcagc gcgatcgtaa tcacccgagt gtgatcatct ggtcgctggg gaatgagtca
    18181 ggccacggcg ctaatcacga cgcactctat cgctggatca aatctgtcga tccatcccgc
    18241 ccggtgcagt atgaaggcgg cggagccgac accacggcca ccgatattat ttgcccgatg
    18301 tacgcgcgcg tggatgaaga ccagcccttc ccggctgtgc cgaaatggtc catcaaaaaa
    18361 tggctttcgc tacctggaga gacgcgcccg ctgatccttt gcgaatacgc ccacgcgatg
    18421 ggtaacagtc ttggcggctt cgctaaatac tggcaggcgt ttcgtcagta cccccgttta
    18481 cagggcggct tcgtctggga ctgggtggat cagtcgctga ttaaatatga tgaaaatggc
    18541 aatccgtggt cggcttacgg cggtgatttt ggcgatacgc cgaacgatcg ccagttctgc
    18601 atgaacgggt tggtctttgc cgaccgcacg ccgcatccgg cgctgacgga agcaaaacac
    18661 caacagcagt ttttccagtt ccgtttatcc gggcggacca tcgaagtgac cagcgaatac
    18721 ctgttccgtc atagcgataa cgaactcctg cactggtcgg tggcgctcga tggcaagccg
    18781 ctggcaagcg gtgaagtgcc tctggatgtt gctccacaag ataaacaggt gattgaactg
    18841 cctgaactac cgcagccgga aagcaccgga caactctggc ttacggtaca cgtagtgcaa
    18901 ccgaatgcga ccgcatggtc agaagccaga cacattagcg cctggcagca gtggcgtctg
    18961 gcggaaaacc tcagcgtgac actcccctcc gcgccccacg ccatcccgca actgaccacc
    19021 agcgaaacgg atttttgcat cgagctgggt aataaacgtt ggcaatttaa ccgccagtca
    19081 ggctttcttt cacagatgtg gattggcgat gaaaaacaac tgctgacgcc gctgcgcgat
    19141 cagttcaccc gtgcaccgct ggataacgac attggcgtaa gtgaagcgac ccgcattgac
    19201 cctaacgcct gggtcgaacg ctggaagacg gcgggccatt accaggccaa agcagcgttg
    19261 ttgcagtgca cggcagatac acttgccgac gcggtgctga ttacgaccgc tcacgcgtgg
    19321 cagcatcagg ggaaaacctt atttatcagc cggaaaacct accggattga tggtagtggt
    19381 caaatggcga ttaccgttga tgttgaagta gcgagcgatg caccgcatcc ggcacggatt
    19441 ggcctgacct gccagctggc gcaggtcgca gagcgggtaa actggctcgg attagggccg
    19501 caagaaaact atcccgaccg ccttactgcc gcctgttttg accgctggga tctgccattg
    19561 tcagacatgt atacccctta cgtcttcccg agcgaaaacg gtctgcgctg cgggacgcgc
    19621 gaattgaatt atggcccaca ccagtggcgc ggcgacttcc agttcaatat cagtcgctac
    19681 agccaacaac aactgatgga aaccagccat cgccatctgc tgcacgcgga agaaggcaca
    19741 tggctgaata tcgacggttt ccatatgggg attggtggcg acgactcctg gagcccgtca
    19801 gtgtcggcgg aattccagct gagcgccggt cgctaccatt accagttggt ctggtgtcaa
    19861 aaataataat aaccgggcag gccatgtctg cccgtatttc gcgtaaggaa atccattatg
    19921 tactatttaa aaaacacaaa cttttggatg ttcggtttat tctttttctt ttactttttt
    19981 atcatgggag cctacttccc gtttttcccg atatggctac atgacatcaa ccatatcagc
    20041 aaaagtgata cgggtattat ttttgctgct atttctctgt tctcgctatt attccaaccg
    20101 ctgtttggtc tgctttctga caaactcggg ctgcgcaaat acctgctgtg gattattacc
    20161 ggcatgttag tgatgtttgc gccgttcttt atttttatct tcggaccact gttacaatac
    20221 aacattttag taggatcgat tgttggtggt atttatcttg gcttttgttt taacgccggt
    20281 gcgccagcag tagaggcatt tatcgagaaa gtcagccgtc gcagtaattt cgaatttggt
    20341 cgcgcgcgga tgtttggctg tgttggctgg gcgctgtgtg cctcgattgt cggcatcatg
    20401 ttcaccatca ataatcagtt tgttttctgg ctgggttctg gctgtgcact catcctcgcc
    20461 gttttactct ttttcgccaa aacggatgca ccctcttccg ccacggttgc caatgcggta
    20521 ggtgccaacc attcggcatt tagccttaag ctggcgctgg aactgttcag acagccaaaa
    20581 ctgtggtttt tgtcactgta tgttattggc gtttcctgca cctacgatgt ttttgaccaa
    20641 cagtttgcta atttctttac ttcgttcttt gctaccggtg aacagggtac gcgggtattt
    20701 ggctacgtaa cgacaatggg cgaattactt aacgcctcga ttatgttctt tgcgccactg
    20761 atcattaatc gcatcggtgg gaaaaacgcc ctactgctgg ctggcactat tatgtctgta
    20821 cgtattattg gctcatcgtt cgccacctca gcgctggaag tggttattct gaaaacgctg
    20881 catatgtttg aagtaccgtt cctgctggtg ggctgcttta aatatattac cagccagttt
    20941 gaagtgcgtt tttcagcgac gatttatctg gtctgtttct gcttctttaa gcaactggcg
    21001 atgattttta tgtctgtact ggcgggcaat atgtatgaaa gcatcggttt ccagggcgct
    21061 tatctggtgt tgggtctggt ggcgctgggc ttcaccttaa tttccgtgtt cacgcttagc
    21121 ggccccggcc cgctttctct actgcgtcgt caggtgaatg aagtcgctta agcaatcaat
    21181 gtcggatgcg gcgcgagcgc cttatccgac caacatatca ggacggaatg atcgcaatga
    21241 acatgccaat gaccgaaaga ataaaagcag gcaagctatt taccgatatg tgcgaaggct
    21301 taccggaaaa aagacttcgt gggaaaacgt taatgtatga gtttaatcac tcgcatccat
    21361 cagaagttga aaaaagagaa agcctgatta aagaaatgtt tgccacggta ggggaaaacg
    21421 cctggataga accacccgtc tatttctctt acggttccaa catccatata ggccgcaatt
    21481 tttatgcaaa tttcaattta accattgtag acgactacac ggtaacgatc ggtgataacg
    21541 tattgattgc acccaatgtt actctttccg ttacgggaca ccctgtacac catgaattga
    21601 gaaaaaacgg cgagatgtac tcttttccga taacgattgg caataacgtc tggatcggaa
    21661 gtcatgtggt cattaatcct ggcgtcacca tcggggataa tgctgttatt ggcgcgggta
    21721 gtgtcgtcac aaaagacatt ccaccaaacg tcgtggctgc tggcgttcct tgtcgggtta
    21781 ttcgcgaaat aaacgaccgg gataagcact attattacaa agattataaa gttgaacctt
    21841 c
//
LOCUS       DADXDL010000080        21834 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.080, whole genome shotgun sequence.
ACCESSION   DADXDL010000080 DADXDL010000000
VERSION     DADXDL010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21834)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21834)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21834
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.080"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..201)
                     /locus_tag="IRB70_003546"
     CDS             complement(<1..201)
                     /locus_tag="IRB70_003546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000961353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5507 domain-containing protein"
                     /protein_id="HBC0633412.1"
                     /translation="MLVSKSNGHNVNTVLGSGSCNENNSSNPMELLAYSIINLICKEA
                     ASGMYRGALETLQKIMSECIYQE"
     gene            complement(958..1033)
                     /locus_tag="IRB70_003547"
     tRNA            complement(958..1033)
                     /locus_tag="IRB70_003547"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(998..1000),aa:Ile,seq:cat)
     gene            1590..3842
                     /locus_tag="IRB70_003548"
     CDS             1590..3842
                     /locus_tag="IRB70_003548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633413.1"
                     /translation="MFSIKPGPGNLPIDNPTLLSWNITDGNLNSKLNTLEYLNCITNI
                     INACGVYPQDLKDKEIISTFHAEKVINDLLKNDYKISLSPDTTYRELNKAAQRSITAP
                     DRIGEGKTWVYQRDTMVERGDNRGVHQYGPAEHFTHIISDKPSPKDKYVAYAINIPDY
                     ELAADVYNINVTSPSGQQETFKILINPEHLRQTLERKSLTAVQKSQCEIITPKKPGEA
                     ILHAFNATYQQIRENMSEFARSHYGYIQIPPVTTFRADGPETPEEEKGYWFHAYQPED
                     LCTIHNPMGDLQDFIALVKDAKKFGIDIIPDYTFNFMGIGGSGKNDLDYPSADIRAKI
                     SKDIESGIPGYWQGQVLIPFTIDPVTKERKQIHPEDIHLTAKDFETSKDNISKDEWEN
                     LHALKEKRLNGMPKTTPKSDQVIMLQNQYVREMRKYGVRGLRYDAAKHSKHEQIERSI
                     TPPLTIYNERLHNTNLFNPIYHEKAVMNYMEYLVTCQLDEEQMSSLLYERDDLSAIDF
                     SLLMKTIKAFSFGGDLQTLASKPGSTISSIPSKRRILININHDFPNNGNLFNDFLFNH
                     QQDEQLAMAYMAALPFSRPLVYWDGQVLKSTTEIKNYDGSTRVGGEAWLNKGCSTYQQ
                     LYNEFHALYIDKAGIWSAFEGVFATKNVLAFSRGDSVNINHSPHDGLVIINKGNEEVE
                     GTWPNKLQPGIYKNMGSNSVNIIINNTRKIIPPGKAFMLRGGTLNINIPGRSALLLGK
                     TGEPPNYLYL"
     gene            4179..5156
                     /gene="csiD"
                     /locus_tag="IRB70_003549"
     CDS             4179..5156
                     /gene="csiD"
                     /locus_tag="IRB70_003549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311547.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbon starvation induced protein CsiD"
                     /protein_id="HBC0633414.1"
                     /translation="MNALTAVQNNAVDSGQDYSGFTLIPSAQSPRLLELTFTEQTTKQ
                     FLEQVAEWPVQALEYKSFLRFRVGKILDDLCANQLQPLLLKTLLNRAEGALLINAVGV
                     DDVKQADEMVKLATAVAHLIGRSNFDAMSGQYYARFVVKNVDNSDSYLRQPHRVMELH
                     NDGTYVEEITDYVLMMKIDEQNMQGGNSLLLHLDDWEHLDHYFRHPLARRPMRFAAPP
                     SKNVSKDVFHPVFDVDQQGRPVMRYIDQFVQPKDFEEGVWLSELSDAIETSKGILSVP
                     VPVGKFLLINNLFWLHGRDRFTPHPDLRRELMRQRGYFAYATNHYQTHQ"
     gene            5176..6444
                     /gene="lhgO"
                     /locus_tag="IRB70_003550"
     CDS             5176..6444
                     /gene="lhgO"
                     /locus_tag="IRB70_003550"
                     /EC_number="1.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311548.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-2-hydroxyglutarate oxidase"
                     /protein_id="HBC0633415.1"
                     /translation="MYDFVIIGGGIIGMSTAMQLIDVYPDARIALLEKESGPAFHQTG
                     HNSGVIHAGVYYTPGSLKAQFCLAGNRATKAFCDQNGIRYDNCGKMLVATSELEMERM
                     RALWERTAANGIEREWLNAEELREREPNITGLGGIFVPSSGIVSYREVTAAMAKIFQA
                     RGGEIIYNAEVSALSEHKNGVVIRTRQGGEYEASTLISCSGLMADRLVKMLGLEPGFI
                     ICPFRGEYFRLAPEHNQIVNHLIYPIPDPAMPFLGVHLTRMIDGSVTVGPNAVLAFKR
                     EGYRKRDFSFSDTLEILGSSGIRRVLQNHLRSGLGEMKNSLCKSGYLRLVQKYCPRLS
                     LSDLQPWPAGVRAQAVSPDGKLIDDFLFVTTPRTIHTCNAPSPAATSAIPIGAHIVSK
                     VQTLLASQSNPGRTLRAARSVDALHAAFNQ"
     gene            6467..7915
                     /gene="gabD"
                     /locus_tag="IRB70_003551"
     CDS             6467..7915
                     /gene="gabD"
                     /locus_tag="IRB70_003551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent succinate-semialdehyde
                     dehydrogenase"
                     /protein_id="HBC0633416.1"
                     /translation="MKLNDSNLFRQQALINGEWLDANNGEVIEVTNPANGDKLGSVPK
                     MGADETRAAIDAANRALPAWRALTAKERANILRNWFNLMMEHQDDLARLMTLEQGKPL
                     AEAKGEISYAASFIEWFAEEGKRIYGDTIPGHQADKRLIVIKQPIGVTAAITPWNFPA
                     AMITRKAGPALAAGCTMVLKPASQTPFSALALAELAIRAGVPAGVFNVVTGSAGAVGN
                     ELTSNPLVRKLSFTGSTEIGRQLMEQCAKDIKKVSLELGGNAPFIVFDDADLDKAVEG
                     ALASKFRNAGQTCVCANRLYVQNGVYDRFAEKLQQAVSKLHIGNGLEKGVTIGPLIDE
                     KAVAKVEEHIADALEKGARVVCGGKADERGGNFFQPTILVDVPANAKVSKEETFGPLA
                     PLFRFKDEADVIAQANDTEFGLAAYFYARDLSRVFRVGEALEYGIVGINTGIISNEVA
                     PFGGIKASGLGREGSKYGIEDYLEIKYMCIGL"
     gene            7929..9209
                     /gene="gabT"
                     /locus_tag="IRB70_003552"
     CDS             7929..9209
                     /gene="gabT"
                     /locus_tag="IRB70_003552"
                     /EC_number="2.6.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000097653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-aminobutyrate--2-oxoglutarate transaminase"
                     /protein_id="HBC0633417.1"
                     /translation="MSSNKELMQRRSQAIPRGVGQIHPIFADRAENCRVWDVEGREYL
                     DFAGGIAVLNTGHLHPKVVVAVEAQLKKLSHTCFQVLAYEPYLELCEIMNQKVPGDFA
                     KKTLLVTTGSEAVENAVKIARAATKRSGTIAFSGAYHGRTHYTLALTGKVNPYSAGMG
                     LMPGHVYRALYPCPLHGISEDDAIASIHRIFKNDAAPEDIAAIVIEPVQGEGGFYAAT
                     PAFMQRLRALCDEHGIMLIADEVQSGAGRTGTLFAMEQMGVAPDLTTFAKSIAGGFPL
                     AGVTGRAEVMDAVAPGGLGGTYAGNPIACVAALEVLKVFEQENLLQKANVLGQKLKDG
                     LLAIAEKHPEIGDVRGLGAMIAIELFEDGDPSKPDAKLTAEIVARARDKGLILLSCGP
                     YYNVLRILVPLTIEDAQIRQGLEIISQCFAEAKL"
     gene            9446..10846
                     /gene="gabP"
                     /locus_tag="IRB70_003553"
     CDS             9446..10846
                     /gene="gabP"
                     /locus_tag="IRB70_003553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GABA permease"
                     /protein_id="HBC0633418.1"
                     /translation="MGQSSQPHELGGGLKSRHVTMLSIAGVIGASLFVGSSVAIAEAG
                     PAVLLAYLFAGLLVVMIMRMLAEMAVATPDTGSFSTYADKAIGRWAGYTIGWLYWWFW
                     VLVIPLEANIAAMILHSWVPGIPIWLFSLVITLALTGSNLLSVKNYGEFEFWLALCKV
                     IAILAFIFLGAVAISGFYPYAEVSGISRLWDSGGFMPNGFGAVLSAMLITMFSFMGAE
                     IVTIAAAESDTPEKHIVRATNSVIWRISIFYLCSIFVVVALIPWNMPGLKAVGSYRSV
                     LELLNIPHAKLIMDCVILLSVTSCLNSALYTASRMLYSLSRRGDAPAVMGKINRSKTP
                     YVAVLLSTGAAFLTVVVNYYAPAKVFKFLIDSSGAIALLVYLVIAVSQLRMRKILRAE
                     GSEIRLRMWLYPWLTWLVIGFITFVLVVMLFRPAQQLEVISTGLLAIGIICTVPIMAR
                     WKKLIMWQKTPIHNTR"
     gene            10867..11529
                     /gene="csiR"
                     /locus_tag="IRB70_003554"
     CDS             10867..11529
                     /gene="csiR"
                     /locus_tag="IRB70_003554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311552.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator CsiR"
                     /protein_id="HBC0633419.1"
                     /translation="MTITSLDGYRWLKNDIIRGNFQPDEKLRMSLLTSRYALGVGPLR
                     EALSQLVAERLVTVVNQKGYRVASMSEQELLDIFDARANMEAMLVSLAIARGGDEWEA
                     DVLAKAHLLSKLEACDASEKMLDEWDLRHQAFHTAIVAGCGSYYLLQMRERLFDLAAR
                     YRFIWLRRTVLSVEMLEDKHDQHQTLTAAVLARDTARASELMRQHLLTPIPIIQQAMA
                     GN"
     gene            complement(11530..11979)
                     /gene="kbp"
                     /locus_tag="IRB70_003555"
     CDS             complement(11530..11979)
                     /gene="kbp"
                     /locus_tag="IRB70_003555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="potassium binding protein Kbp"
                     /protein_id="HBC0633420.1"
                     /translation="MGLFNFVKDAGEKLWDAVTGQHDKDDQAKKVQEHLNKTGIPDAD
                     KVNIQIADGKATVTGDGLSQEAKEKILVAVGNISGIASVDDQVKTATPATASQFYTVK
                     SGDTLSAISKQVYGNANLYNKIFEANKPMLKSPDKIYPGQVLRIPEE"
     gene            complement(12063..12221)
                     /locus_tag="IRB70_003556"
     CDS             complement(12063..12221)
                     /locus_tag="IRB70_003556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaE/Pmp3 family membrane protein"
                     /protein_id="HBC0633421.1"
                     /translation="MGFWRIVITIILPPLGVLLGKGFGWAFIINILLTLLGYIPGLIH
                     AFWVQTRD"
     gene            12404..12703
                     /locus_tag="IRB70_003557"
     CDS             12404..12703
                     /locus_tag="IRB70_003557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0633422.1"
                     /translation="MTELAQLQASAEQAAALLKAMSHPKRLLILCMLSGSPGTSAGEL
                     TRITGLSASATSQHLARMRDEGLIDSQRDAQRILYSIKNEAVNAIIATLKNVYCP"
     gene            12713..13237
                     /gene="ygaP"
                     /locus_tag="IRB70_003558"
     CDS             12713..13237
                     /gene="ygaP"
                     /locus_tag="IRB70_003558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiosulfate sulfurtransferase YgaP"
                     /protein_id="HBC0633423.1"
                     /translation="MALTTISPHDAQELIARGAKLIDIRDADEYLREHIPEADLAPLS
                     VLEQSGLPAKLCREQIIFHCQAGKRTSNNADKLAAIAAPAEIFLLEDGIDGWKKAGLP
                     VTVNKSQPLPLMRQVQIAAGGLILIGVILGYTVNSGFFLLSGFVGAGLLFAGISGFCG
                     MARLLDKMPWNQRA"
     gene            complement(13284..13688)
                     /gene="stpA"
                     /locus_tag="IRB70_003559"
     CDS             complement(13284..13688)
                     /gene="stpA"
                     /locus_tag="IRB70_003559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein StpA"
                     /protein_id="HBC0633424.1"
                     /translation="MSVMLQSLNNIRTLRAMAREFSIDVLEEMLEKFRVVTKERREEE
                     EQQQRELAERQEKISTWLELMKADGINPEELLGNSSAAAPRAGKKRQPRPAKYKFTDV
                     NGETKTWTGQGRTPKPIAQALAEGKSLDDFLI"
     gene            14356..14805
                     /gene="alaE"
                     /locus_tag="IRB70_003560"
     CDS             14356..14805
                     /gene="alaE"
                     /locus_tag="IRB70_003560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-alanine exporter AlaE"
                     /protein_id="HBC0633425.1"
                     /translation="MFSPQSRLRHAVADTFAMVVYCSVVNMCIEVFLSGMSFEQSFYS
                     RLVAIPVNILIAWPYGMYRDLFMRAARKVSPSGWIKNLADIMAYVTFQSPVYVAILLV
                     VGADWHQIMAAVSSNIVVSMLMGAVYGYFLDYCRRLFKVSRYQQVKA"
     gene            complement(14842..15186)
                     /locus_tag="IRB70_003561"
     CDS             complement(14842..15186)
                     /locus_tag="IRB70_003561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgaC family protein"
                     /protein_id="HBC0633426.1"
                     /translation="MYLRPDEVARVLEKVGFTVDVVTQKAYGYRRGENYVYVNREARM
                     GRTALVIHPTLKERSSTLAEPASDIKTCDHYQQFPLYLAGERHEHYGIPHGFSSRVAL
                     ERYLNGLFGEAS"
     gene            15338..15667
                     /locus_tag="IRB70_003562"
     CDS             15338..15667
                     /locus_tag="IRB70_003562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311560.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HBC0633427.1"
                     /translation="MFNRPNRNDVDDGVQDIQNDVNQLADSLESVLKSWGSDAKGEAE
                     AARSKAQALLKETRARMHGRTRVQQAARDAVGCADSFVRERPWCSVGTAAAVGIFIGA
                     LLSMRKS"
     gene            complement(15724..17058)
                     /locus_tag="IRB70_003563"
     CDS             complement(15724..17058)
                     /locus_tag="IRB70_003563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBC0633428.1"
                     /translation="MPRYQDIARQLKTAIEQGELKPGARLPSSRTWSQELGVSRSTVE
                     NAYAELVAQGWLIRRGQAGTFVSERIYPQQSTVQVVAFAGESQQPLPFQMGLPALDLF
                     PRELWARVMGRRLRTQTRFDLALGDVCGEAALREAIVDYLRVSRGIDCQPEQVFITHG
                     YAASIALILHALAKPGNGMWIEDPGFPLIRPIVTRHDVEILPVPVDDNGLDITSGIQN
                     YPDARFALITPAHQSPLGVALSLARRHQILEWADRSQAWIIEDDYDSEFRYHGKPLPA
                     LKSLDAPQRVIYAGTFSKALFPALRCAWLVVPVKQIAQFRHQASLAPCAVPVLWQNTL
                     ADFLREGHFWRHLKKMRQHYAQRRQWIEQALTQQGFQVVPQKGGIQMVIRMIGDDIAH
                     ARKANAAGLAVQALSDWRIRSSGEGGLLLSFTNIVNEGMARQVAQQLRKALS"
     gene            17146..17577
                     /locus_tag="IRB70_003564"
     CDS             17146..17577
                     /locus_tag="IRB70_003564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBC0633429.1"
                     /translation="MTTLRQPYYELSPAVYNALVQAKTALENSTLDTTLMELVYLRVS
                     QINGCAFCLEMHSKALRKSGVPQHKLDALAGWRVSHHFDERERAALAWAESVTEIART
                     HAEDEVYQPLLEHFSAAEISDLTFAIGLMNCFNRLAVSMRM"
     gene            17786..18031
                     /gene="nrdH"
                     /locus_tag="IRB70_003565"
     CDS             17786..18031
                     /gene="nrdH"
                     /locus_tag="IRB70_003565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBC0633430.1"
                     /translation="MRITIYTRNDCVQCHATKRAMENRGFDFEMINVDRVPEAAEALR
                     AQGFRQLPVVIAGDLSWSGFRPDMINRLHPAPHAASA"
     gene            18028..18438
                     /gene="nrdI"
                     /locus_tag="IRB70_003566"
     CDS             18028..18438
                     /gene="nrdI"
                     /locus_tag="IRB70_003566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBC0633431.1"
                     /translation="MSQLVYFSSSSENTQRFIERLGLPAVRIPLNERERIQVDEPYIL
                     IVPSYGGGGTTGAVPRQVIRFLNDEHNRALLRGVIASGNRNFGEAYGRAGDVIARKCG
                     VPWLYRFELMGTQSDIENVRKGVTEFWQRQPQNA"
     gene            18411..20555
                     /gene="nrdE"
                     /locus_tag="IRB70_003567"
     CDS             18411..20555
                     /gene="nrdE"
                     /locus_tag="IRB70_003567"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBC0633432.1"
                     /translation="MATTTAERLTQETMDYHALNAMLNLYDSAGRIQFDKDLQAVDAF
                     MTTHVRPNSVAFSSQQQRLNWLVNEGYYDESVLNRYSRDFVITLFAHAHASGFRFQTF
                     LGAWKFYTSYTLKTFDGKRYLEDFADRVTMVALTLAQGDETLATQLTDEMLSGRFQPA
                     TPTFLNCGKQQRGELVSCFLLRIEDNMESIGRAVNSALQLSKRGGGVAFLLSNLREAG
                     APIKRIENQSSGVIPVMKMLEDAFSYANQLGARQGAGAVYLHAHHPDILRFLDTKREN
                     ADEKIRIKTLSLGVVIPDITFHLAKENAQMALFSPYDVERVYGKPFADVAISERYDEL
                     VADERIRKKYLNARDFFQRLAEIQFESGYPYIMYEDTVNRANPIAGRINMSNLCSEIL
                     QVNSASEYDENLDYARTGHDISCNLGSLNIAHTMDSPDFARTVETAVRGLTAVSDMSH
                     IRSVPSIEAGNAASHAIGLGQMNLHGYLAREGIAYGSPEALDFTNLYFYTITWHALRT
                     SMLLARERGETFAGFKQSRYASGEYFSQYLQSNWQPKTAKVGELFARSGITLPTREMW
                     AQLRDDVMRYGIYNQNLQAVPPTGSISYINHATSSIHPIVAKVEIRKEGKTGRVYYPA
                     PFMTNENLALYQDAYEIGAEKIIDTYAEATRHVDQGLSLTLFFPDTATTRDINKAQIY
                     AWRKGIKTLYYIRLRQMALEGTEIEGCVSCAL"
     gene            20565..21524
                     /gene="nrdF"
                     /locus_tag="IRB70_003568"
     CDS             20565..21524
                     /gene="nrdF"
                     /locus_tag="IRB70_003568"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBC0633433.1"
                     /translation="MKLSRISAINWNKISDDKDLEVWNRLTSNFWLPEKVPLSNDIPA
                     WQTLSVVEQQLTMRVFTGLTLLDTLQNVIGAPSLMPDALTPHEEAVLTNISFMEAVHA
                     RSYSSIFSTLCQTKDVDAAYAWSEENAPLQRKAQIIQQHYRGDDPLKKKIASVFLESF
                     LFYSGFWLPMYFSSRGKLTNTADLIRLIIRDEAVHGYYIGYKYQKNMEKISQAQREEL
                     KSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNANKALMNLGYEPLFPAEMA
                     EVNPAILAALSPNADENHDFFSGSGSSYVMGKAVETEDEDWNF"
BASE COUNT         5618 a         5339 c         5324 g         5553 t
ORIGIN      
        1 ttcttgatat atacattcag acattatttt ttgtaaagtt tcaagagcac cgcgatacat
       61 ccctgaggca gcttccttac aaattaaatt tataatacta taagctagta gctccatggg
      121 gttggaagaa ttgttttcat tacaacttcc actacccaaa actgtattaa cgttatgacc
      181 attactttta ctaactaaca ttgtctattc ctcagttaat gtctacatgg ctatgtttaa
      241 cgttattact gtttgtcatt ataaaaaacc gctcatttga gacaattgct gacattaact
      301 gtttcacttg ctacgcatgg actttttaat taaattagca caagaatgtt aaatttaata
      361 aacaaaaagt tatttcgctg tatgataaaa accaaccgtt atgatttatt agtggaattc
      421 gtttttcgag tgttagaaat ttatatctaa atagcgttaa ttaatgagca aagccagact
      481 cctgtaacgc tcataagact catctgcctg cgacgggtgg tctggtcagt agtagatgtt
      541 taaggcgtgg cagagacatt tcatccttac tctacggcat tggtccacat acaaatcgtg
      601 gttgtgacac ttcacttatc atcagtgagc gaacagagaa tagttcagtg atttgagtaa
      661 ttaacctgat taaatgaaaa ggcatgataa atgataatac tctggcttta tcgttaatta
      721 cttaattcca catgtaagca atttgcccgc ttggcatagc gggcattttt tccaggtact
      781 tttgaatgag tactgatgga taaatacatt gcagtggcgt gccacgtacc aaaacaccag
      841 ccctcattcg aaaccaccta ccgcactgct tctttaaaat ggcgttagtc gtgaaatatt
      901 gaccgccatc gagtccccct tgtaacctta actcttcctg atacatgaat gatgatttgg
      961 tggcccctgc tggacttgaa ccagcgacca ggcgattatg agtcgcctgc tctaaccact
     1021 gagctaaagg gccttaagta tgcaataaca atacttataa accaagcaat aaacatgatg
     1081 attatatgat gtaaataaga gattttatgc gttctcatcc atcctgggtc gtaattacac
     1141 gcgacataaa tcccgacacc gcttccattc gcaaagtcga tactcgcagt caacaagcat
     1201 gttaataata agcactatct atagttatca tcgattcaat gatagtttgt aatgattttg
     1261 tatctaataa tataacttta ttacattagc agaagagttt tcgcatcatg atgatatctg
     1321 ttacttttca ctccataaaa ataaacttca tatagcaata tattctttta tagaacttat
     1381 tctgctaatc attagtttcg tatgagcgat ttttgacagt tgcctctcca gaccacatcg
     1441 ataattaaaa aaacagattt aagcattatc cttttccata tgaatattgg ataaaagtag
     1501 gacatctgtt tgcaattact ttcacaacaa ttaaacattt ttatgtttcc gtatacacct
     1561 tattactcta ccattagagg aactttatta tgttttctat aaaaccagga ccaggaaatt
     1621 tacctatcga caaccccaca ttgttatcat ggaacattac tgacgggaat ctaaattcca
     1681 aattaaatac attagaatat ctaaactgta taacaaatat tattaatgct tgtggagttt
     1741 atcctcagga tttaaaagac aaagaaatta tatcaacttt tcacgcagaa aaagtcatta
     1801 atgatctgtt aaaaaacgat tataaaattt ccctttctcc agatacaact taccgagagc
     1861 tgaataaagc tgcacagcgt agcattacag cgccagacag gataggagaa gggaaaacat
     1921 gggtttatca acgagataca atggttgaaa gaggtgataa cagaggcgtt catcagtatg
     1981 gtccagctga acatttcact cacattatat ctgacaaacc atccccaaaa gataagtatg
     2041 ttgcatatgc tattaacatt cctgactatg agctagcagc cgatgtatat aatattaatg
     2101 tgacgtcacc ttccggacag caagaaacat ttaaaatact aatcaatcca gaacatctac
     2161 ggcaaacact tgagcgtaaa tctcttactg ctgttcagaa atcacaatgt gaaatcatca
     2221 cccccaaaaa acctggcgaa gcgattcttc atgcttttaa tgccacctac cagcaaatca
     2281 gggaaaatat gtctgagttt gcacgttccc attatgggta tatacaaatt cctccagtga
     2341 caactttccg cgccgacgga ccagaaactc ccgaagaaga aaaaggttac tggtttcacg
     2401 cttatcaacc cgaagatctt tgtaccatcc ataatccaat gggagatttg caggatttta
     2461 tcgcattggt taaagatgct aaaaaatttg gtatcgatat cattcctgat tataccttta
     2521 actttatggg aattgggggt agtggtaaaa atgacctgga ttatccctct gctgatatac
     2581 gagcgaagat cagtaaagat atagaaagtg gtatccctgg ctattggcaa ggtcaggttt
     2641 tgattccatt tactatagat ccagtaacaa aagaacgtaa acaaatccat ccagaagata
     2701 tacatctcac tgcaaaagac tttgaaacaa gtaaagataa catctctaag gatgaatggg
     2761 aaaacctcca tgcattaaaa gaaaagcgtt taaatggaat gcctaaaaca acccccaaaa
     2821 gtgaccaggt tattatgttg caaaatcaat acgttcgtga aatgcgaaaa tatggcgtac
     2881 gaggtttacg ttacgatgca gcaaaacact caaaacatga acaaatagaa agatcaataa
     2941 ctccaccgct tacaatttat aatgagcgat tacacaatac taacttattt aacccaatat
     3001 atcatgaaaa agccgttatg aattacatgg aatatctggt aacttgtcag ttggatgaag
     3061 aacaaatgtc atcgctgctt tatgaaagag atgatttaag cgccattgat ttttcattgc
     3121 tcatgaagac gataaaagcc ttttcatttg gtggcgatct ccaaaccctt gcatcaaaac
     3181 cgggttcaac aatctcaagc atcccgtcaa aaagacggat attgattaac attaaccacg
     3241 attttcctaa caatggcaat cttttcaatg actttctatt taaccatcaa caagatgaac
     3301 aattagcaat ggcatatatg gccgctctcc cgttcagcag gcctttagtt tactgggatg
     3361 gccaagtatt aaaatcaacg actgaaatta aaaattatga tgggtcgacg cgtgtcggcg
     3421 gtgaggcgtg gcttaataaa ggttgctcta cctatcagca gctctacaat gaattccacg
     3481 cattatatat agataaagca ggaatatgga gcgcatttga gggtgtattt gcaactaaaa
     3541 acgttctggc ctttagtcgt ggggattctg tgaacattaa tcactctcct catgatggac
     3601 tagttataat aaataaagga aacgaagaag ttgaaggtac ctggcctaac aaattgcaac
     3661 ctggaatata taaaaacatg gggagtaata gcgttaacat tattattaat aatacccgaa
     3721 aaattatccc ccctggtaaa gcatttatgc ttagaggcgg aactctaaat atcaatattc
     3781 ctgggcgtag cgctcttctt ttagggaaaa ctggagaacc gccgaactat ctctatttgt
     3841 aatttaatgt tatatctgcc ccgctaaaac ggggcagata atatgtttag tttactaacg
     3901 gtcattttgc agtgaagcca tttaccgttt tttatcgacc agaaaatctg ttctctgatg
     3961 gtaatccacc cctaacctgt tgctttagtt attcatttcc tgtctcactt tgccttaata
     4021 cgctacgtta attgttacca atttgttgct tttgatcaca ataagaaaac aatatggcgc
     4081 atttgtgcgc atttttcaga aatgtagata tttttagatt atggctacga aatgagcatc
     4141 gccatgtcac cctacatctc ataagaggat cgcttctgat gaatgcactg accgccgtac
     4201 aaaataacgc tgtcgattca ggccaggact atagcggatt cactctcatc ccgtcggcgc
     4261 aatccccgcg tctgctggaa ctcaccttca ccgaacagac gaccaaacag tttctcgaac
     4321 aggttgccga atggcccgtg caggcgctgg agtacaaatc ttttctgcgt tttcgggtag
     4381 gcaaaattct tgacgatctg tgtgcgaacc agctgcaacc attgctgttg aagaccctgc
     4441 taaaccgtgc tgaaggtgcg ctgttgatca atgcggtggg tgtcgatgat gtgaagcaag
     4501 cggatgagat ggtgaagctg gcaacggcgg tagcgcatct gattggccgt tccaatttcg
     4561 atgcgatgag cggtcagtat tacgcgcgtt ttgtagtgaa aaatgtcgat aactcagaca
     4621 gctatctgcg tcagccgcac cgcgtaatgg agctgcataa cgacggcacc tacgtcgaag
     4681 agatcactga ctatgtgctg atgatgaaaa tcgacgagca gaacatgcag ggtggaaatt
     4741 cgttgctgct gcatctcgat gactgggaac atctggacca ctatttccgc cacccgctgg
     4801 cgcgtcgccc gatgcgcttt gccgcgccgc cgagcaaaaa cgtcagcaaa gatgttttcc
     4861 atccggtgtt cgacgttgat caacagggtc gcccggtgat gcgttatatc gaccagttcg
     4921 tccagccaaa agacttcgaa gaaggcgtgt ggctgagcga gctttccgat gccattgaaa
     4981 ccagcaaagg cattctttct gtgcccgttc ccgttggcaa attcctgttg attaacaatc
     5041 tattctggct gcacggtcgc gaccgcttta ctccgcaccc ggatctgcgc cgtgaactga
     5101 tgcgtcagcg tggctatttc gcttacgcca ctaaccacta ccagacgcat cagtaagcgc
     5161 aaaggaattg agcggatgta tgattttgtg attattggcg gcggcatcat cggcatgtcg
     5221 accgccatgc aactgattga tgtttatccg gatgcccgca ttgcgttgct ggaaaaagag
     5281 tccggcccgg cctttcatca gacgggccac aacagcggcg tgatccatgc cggggtctat
     5341 tacacgcccg gtagcctgaa ggcacagttt tgcctggcgg gaaaccgcgc caccaaagcc
     5401 ttttgcgatc aaaacggcat tcgctatgac aactgcggca agatgctggt cgccacctct
     5461 gaactcgaaa tggaacggat gcgcgcgttg tgggaacgca cggcggcgaa cggtatcgag
     5521 cgcgagtggt taaacgccga ggaactgcgc gagcgcgaac cgaatatcac cgggctcggc
     5581 ggcatttttg tgccgtccag cggcattgtc agctatcgcg aagtgacggc ggcgatggca
     5641 aaaatcttcc aggccagagg cggcgagatt atttataacg ccgaagtcag cgccctcagt
     5701 gagcataaaa acggcgtggt gatacgtacc cgtcagggcg gtgaatatga agcatcgacg
     5761 ctgattagct gttccgggct gatggctgac cggctggtga aaatgctcgg cctcgaaccg
     5821 ggctttatta tctgcccgtt ccgtggcgag tatttccgcc ttgcgccgga gcataaccag
     5881 attgttaacc acctgattta ccccattccc gaccccgcga tgccattttt gggcgtgcat
     5941 ctcacccgca tgatcgatgg cagcgtgacc gtcgggccaa acgcggtgct ggctttcaaa
     6001 cgtgaaggct atcgcaagcg cgacttctca tttagcgaca cgctggagat tttgggctcg
     6061 tcggggattc gccgggtgct gcaaaaccat ctacgctcag gactgggcga gatgaaaaac
     6121 tcgctgtgca aaagcggcta tctgcggctg gtgcaaaagt attgtccccg gctttcgtta
     6181 agcgatctcc agccctggcc cgccggtgtg cgggcgcagg cggtatcgcc ggacggcaag
     6241 ctgattgacg attttctgtt tgtcaccacc ccgcgcacga tccacacctg caatgcgccc
     6301 tccccggcag cgacatcagc aattcctatt ggtgcgcata ttgtcagcaa ggtacaaacg
     6361 ctgttggcaa gccagagtaa ccccggacgc acgctgcgag cggcacgtag tgtggatgcc
     6421 ttacacgccg catttaatca ataacctttg aaaacaggac gtaacaatga aacttaacga
     6481 cagtaactta ttccgccagc aggcgttaat taacggggag tggctggacg ccaacaatgg
     6541 cgaagtcatc gaggtcacta atccggcaaa cggcgacaag ctgggtagcg tacccaaaat
     6601 gggcgctgat gaaacccgcg ccgctatcga cgccgccaac cgcgccctgc ccgcctggcg
     6661 tgcgctcacc gccaaagaac gcgccaacat tctgcgcaac tggttcaatt tgatgatgga
     6721 gcatcaggac gatttagcgc gcctgatgac cctcgaacag ggcaaaccgc tggcggaagc
     6781 gaaaggcgaa atcagctacg cagcctcttt tattgagtgg tttgccgaag aaggcaaacg
     6841 tatttatggc gataccattc ccggtcatca ggccgacaaa cgcctgattg ttatcaaaca
     6901 gccgattggc gttaccgccg ccatcacgcc gtggaacttc ccggcggcga tgattacccg
     6961 taaagcaggt ccggcgctgg cggcaggctg cacgatggtg ctgaagcccg ccagtcagac
     7021 gccgttctct gcgctggcgc tggcagaact ggcgattcgc gcgggcgttc cggctggcgt
     7081 gtttaacgtg gtcaccggtt cggcgggcgc ggtcggtaac gaactgacca gcaacccgct
     7141 ggtgcgcaag ctgtcgttta ccggctcgac cgaaattggc cgtcagttaa tggaacagtg
     7201 cgcgaaagac atcaaaaaag tgtcgctgga gctgggcggc aacgcaccgt ttattgtctt
     7261 tgacgatgcc gatctcgata aagccgtgga aggcgcgctg gcctcgaaat tccgtaacgc
     7321 cgggcaaacc tgcgtctgcg ccaaccgcct gtatgtgcag aacggcgtgt atgaccgctt
     7381 tgccgaaaaa ttgcagcagg cggtgagcaa actgcacatc ggcaacgggc tggagaaagg
     7441 cgtcaccatc gggccgctga tcgatgaaaa agcggtagca aaagtggaag agcatattgc
     7501 cgatgcgctg gagaaaggtg cgcgtgtggt ttgcggcggt aaagcggatg aacgcggcgg
     7561 caacttcttc cagccgacca ttctggtgga cgttccagcc aacgccaaag tgtcgaaaga
     7621 agagacgttc ggccccctcg ccccactgtt ccgttttaaa gatgaagccg atgtgattgc
     7681 gcaagccaat gacaccgagt ttggccttgc cgcctatttc tacgcccgtg atttaagccg
     7741 cgtcttccgc gtgggcgaag cgctggagta cggcatcgtc ggcatcaata ccggcattat
     7801 ttccaatgaa gtggccccgt tcggcggcat taaagcctcg ggtctgggtc gtgaaggttc
     7861 gaagtatggc atcgaagatt acttagaaat caaatatatg tgcatcggtc tttaactgga
     7921 gaacgcgaat gagcagcaat aaagagttaa tgcagcgccg cagtcaggcg attccccgtg
     7981 gcgttgggca aattcacccg attttcgctg accgcgcgga aaactgccgg gtgtgggacg
     8041 ttgaaggccg tgagtatctt gatttcgcgg gcgggattgc ggtgctcaat accgggcacc
     8101 tgcatccgaa ggtggtggtc gcggtggaag cgcagttgaa aaaactgtcg cacacctgct
     8161 tccaggtgct ggcttacgaa ccgtatctgg agctgtgcga gattatgaat cagaaggtgc
     8221 cgggcgattt cgccaagaaa acgctgctgg ttacgaccgg ttccgaagcg gtggaaaatg
     8281 cggtgaaaat cgcccgcgcc gccaccaaac gtagcggtac tatcgccttt agcggtgcgt
     8341 atcacgggcg cacgcattac acgctggcgc tgaccggtaa ggtgaaccca tactctgcgg
     8401 gcatggggct gatgccgggt catgtttatc gcgcgcttta tccttgcccg ctgcacggca
     8461 taagcgagga tgacgctatc gccagcatcc accggatctt caaaaatgac gccgcgccgg
     8521 aagatatcgc cgccatcgtg attgagcccg ttcagggcga aggcggtttc tacgccgcga
     8581 cgccagcctt tatgcagcgt ttacgcgcgc tgtgtgacga gcacgggatc atgctgattg
     8641 ccgatgaagt gcagagcggc gcagggcgta ccggcacgct gtttgcgatg gagcagatgg
     8701 gcgttgcgcc ggatcttacc acctttgcga aatcgatcgc gggcggcttc ccgctggcgg
     8761 gcgtcaccgg gcgcgcggaa gtgatggatg ccgtcgcacc gggcggactg ggtggcacct
     8821 atgccggtaa cccgattgcc tgcgtagcgg cgctggaagt gttgaaggtg ttcgagcagg
     8881 aaaatctgct gcaaaaagcc aacgttctgg ggcagaagct gaaagacgga ttgctggcga
     8941 tcgccgaaaa acacccggag atcggcgacg tacgcgggct gggggcgatg atcgccatcg
     9001 agctgtttga agatggcgat cccagcaaac cggacgcaaa actcaccgcc gagatcgtgg
     9061 cacgcgcccg cgataagggt ctgattcttc tctcctgcgg cccgtattac aacgtgctgc
     9121 gcatccttgt accgctcacc attgaagacg ctcagatccg tcagggtctg gagatcatca
     9181 gccagtgttt tgctgaggcg aagctgtagc accgcaccat gccggaggcg acgctttgcg
     9241 gcttgtccgg cctacgagaa tccaggtcgg ataaggcgtt tacgccgcat ccgacaatct
     9301 gtacgtgaac aggaataaat ctatgtcggc cggataaggc ggagccgctc tccggcaaaa
     9361 agaaccaata acaattaaac gcgtgacccg acgcgggaaa tgtcggggcg ctctcccaag
     9421 tgacacactt tcgagaggat tcaggatggg gcaatcatcg caaccacatg agttaggcgg
     9481 cgggctgaag tcacgccacg tcaccatgtt gtctattgcc ggtgttatcg gcgcaagtct
     9541 gtttgtcggt tccagcgtcg ccatcgccga agcgggcccg gcggtattac tggcctatct
     9601 gttcgccgga ttactggtgg ttatgattat gcggatgttg gcggaaatgg cggttgccac
     9661 gcccgatacc ggttcgtttt ccacctatgc cgataaagcc attggccgtt gggcgggcta
     9721 taccatcggc tggttgtact ggtggttttg ggtactggtt atcccactgg aagccaacat
     9781 cgccgccatg atcctgcact cgtgggttcc aggcattccc atctggttat tttccctggt
     9841 cattaccctc gccttgactg gcagtaattt attaagcgtt aaaaactacg gcgaatttga
     9901 gttctggctg gcgctgtgca aagtcatcgc tatcctggcc tttattttcc ttggtgcagt
     9961 cgcaattagc ggtttttacc cttatgccga agtgagcggg atctcaagat tgtgggatag
    10021 cggcggcttt atgcccaacg gcttcggtgc ggtattaagc gcgatgttga tcaccatgtt
    10081 ctcgtttatg ggcgcagaaa ttgtcactat tgccgccgcg gaatctgaca cgccggaaaa
    10141 acatattgtc cgcgccacca actcggttat ctggcgtatt tctatcttct atttgtgctc
    10201 tatttttgtc gtcgtggcat taataccgtg gaatatgccg gggctgaaag ccgttggatc
    10261 ttatcgctcg gttctggagt tgctcaatat tccccatgcg aaattaatca tggactgcgt
    10321 gatattactt tccgtaacca gttgcctgaa ctcggcgctg tataccgctt ccagaatgct
    10381 ctactcctta agccgtcgcg gtgatgcgcc cgcggtaatg ggtaaaatca accgcagtaa
    10441 aaccccgtat gtggcggtat tactctccac cggcgcggca tttttaacgg tggtggtgaa
    10501 ttattacgcg cctgcgaaag tgtttaaatt tctgatcgac agctccggtg ctatcgccct
    10561 gctggtttat ttagtcatcg ccgtttcaca attgcggatg cgcaaaattc tgcgagcaga
    10621 aggaagcgaa attcgcctgc ggatgtggct ttatccgtgg ctcacctggc tggtcatcgg
    10681 ctttattacc tttgtgttgg tagtgatgct attccgcccg gcgcaacagt tagaagtgat
    10741 ctccaccggc ttattagcga tagggattat ctgtaccgtg ccaattatgg ctcgctggaa
    10801 aaagctgata atgtggcaaa aaacacccat tcataatacg cgctgataat gatcaggagt
    10861 cacaccatga ccattacctc tctggatggc tatcgctggc tgaagaacga tattattcgc
    10921 ggtaattttc aaccggatga aaaattacgg atgagtttgc tgacatcgcg ttatgcactt
    10981 ggcgttgggc cgttacggga agctctttcg caactggtgg cggaacggct ggtcacggtg
    11041 gtgaatcaaa aagggtatcg ggtggcgtct atgtcagagc aggagctgct cgatattttc
    11101 gacgcccgcg ccaatatgga agcgatgctg gtgagtctgg cgattgcccg cggtggcgat
    11161 gaatgggagg cagacgttct cgcaaaagcg catctgctca gtaagcttga ggcctgtgac
    11221 gccagtgaga aaatgcttga tgagtgggat ctgcgtcatc aggcgtttca tactgcaatt
    11281 gtggcgggct gtggttctta ctatttgctg caaatgcgtg aacggttgtt tgatctggca
    11341 gcgcgttatc gctttatctg gctgcggcga acagtgcttt cggtggaaat gctggaagat
    11401 aaacacgatc agcaccagac cctgactgcg gcggtactgg cgcgagatac cgcgcgcgcc
    11461 agtgagttaa tgcgccagca tttactgacg ccaattccca ttatccagca ggcgatggct
    11521 ggcaattaac tactcttcag gaatacgcaa cacttgcccc gggtaaattt tatccgggct
    11581 ttttagcatc ggtttattcg cttcgaagat tttattgtac agattagcgt taccgtagac
    11641 ctgtttggaa atggcactca gagtgtcgcc agacttaacg gtataaaact ggctggcagt
    11701 ggctggtgtc gccgttttca cctgatcatc gacactggca ataccggaaa tattccccac
    11761 cgcaacaagg attttctcct tcgcctcctg acttaagccg tcacccgtga ccgtcgcttt
    11821 gccgtcggca atttgaatgt tcactttatc ggcatcaggt ataccggttt tgttcagatg
    11881 ctcctgcacc ttcttcgcct gatcgtcttt atcgtgctga cctgtaaccg cgtcccagag
    11941 tttttctccg gcatctttca caaaattgaa cagacccata gctacctcat tcgttaacgg
    12001 aaacactcag aaagtgtagc agaggaacgc ggcgcgttaa cgccgcgggg gtgagcacag
    12061 gtttaatcgc gggtttgcac ccaaaacgcg tgaatcaaac cggggatata cccaagcagt
    12121 gtcagcagaa tattaataat gaacgcccaa ccgaaccctt taccgagcag cacgccgagc
    12181 ggcggcagaa tgatggtgat gacgattctc cagaaaccca tatgtactcc ctataagaaa
    12241 attactcatt gtttaaaaag agattttatc tcttaagcgt agtaatttta gcggagcctg
    12301 ccagtttcag cttacgcttt tactctcatt tacgctgctg aggctggtat atgttgcatt
    12361 tttagtttag agtttgctta atttagaaaa tacttaaata actatgactg aactcgcgca
    12421 attacaggcc agtgccgaac aggcagcggc cttattgaaa gcaatgagcc accctaaacg
    12481 attgctgatt ctgtgcatgc ttagcggttc ccccggcacc agcgcgggag agctgactcg
    12541 cattaccgga ctgagtgcct ctgcgacatc acagcatctc gctcgtatgc gggacgaagg
    12601 gcttatcgac agccaacggg atgcccaacg cattctatat tccattaaaa atgaggcggt
    12661 aaatgccatt atcgccaccc tgaaaaatgt ctattgtccg taaggagtca ctatggcttt
    12721 gacaaccatt tcgccgcatg atgcacaaga attaatcgca cgcggcgcaa agttaatcga
    12781 tattcgtgac gctgatgaat atcttcgtga acatattcct gaagcagatc tggctccatt
    12841 atccgtgctg gaacagtcag gtcttccggc taaattatgt cgcgagcaaa ttatattcca
    12901 ctgccaggca ggtaaacgca ccagtaataa cgccgataaa ttagcagcga ttgccgcccc
    12961 cgcagaaatc tttttactcg aagatgggat tgatggctgg aaaaaagcag gattaccagt
    13021 aacggtaaat aaatctcaac ccttgccgtt aatgcgccag gtgcagatcg ctgcgggtgg
    13081 tttaatatta atcggcgtta tactgggtta taccgtaaat agcggtttct tcttattaag
    13141 cggctttgtt ggtgccgggt tactgtttgc aggaattagc ggtttttgtg ggatggcaag
    13201 gttgttagat aagatgccgt ggaaccaacg agcttgagaa gcgacgccgg acgcgccata
    13261 gcggcggcat ccggcctcag taattagatc aggaaatcgt cgagagattt accttctgcc
    13321 agcgcctgag cgattggctt cggtgtacgg ccctgaccgg tccaggtttt agtttcaccg
    13381 ttaacatcgg tgaatttata tttcgccgga cgcggctggc gttttttacc agcgcgtggg
    13441 gcggccgcgg agctattacc caataactct tccgggttaa ttccgtcagc tttcatcagc
    13501 tccagccagg tgctaatttt ttcctggcgc tctgccagtt cacgctgctg ctgttcttct
    13561 tcttcacgtc tttctttagt gacaaccctg aatttttcga gcatttcttc aagaacgtca
    13621 atggagaatt cgcgagccat cgcacggagg gtgcgaatgt tatttaaact ttgtaacatt
    13681 acggacataa taaagaaaac cttttaacgc caaaacaaaa aagtatttcg tcgcgtagtg
    13741 taagcgatca cttattatat ttccacaaaa tttaatctat ttacagtcct gcgcgagatt
    13801 atttcagctg ttattttctg aaactctcag aataatttca agattatata ttagccattt
    13861 tgatgagtaa tttcggttat ttgtgagcag agcggcgctc tctgctcgct aattccgcaa
    13921 gcctgacaaa acaaaaatga ataaaaatgc aatttaaccg aataaatgga aacacccctc
    13981 actggtgctt tctgctgtca atgtacattt tctggcataa aaaatgctga aaatgacccg
    14041 gtcacgacat acaccgaatt ctctacgctt atagcgttac ctcaccccca aaccttcatg
    14101 agtgataata aaggtaaaca catatccaat tgatttaatt aaaaataaat tatatcggca
    14161 tgtaaaaatc cacaatgtac aaaaaacgcg ccgttacgga atattttatc tacaaaaaca
    14221 gattaaataa aaatttttca ctaattgatt agtcatagcc agcgatatac gctatgcgaa
    14281 aatgcagatg gcaatgagat ccactgcttt cacctccatt aacatcccat tacgctttta
    14341 ttaaggagca ttagcatgtt ctcaccgcag tcacgcttgc gtcatgcagt tgcagatacg
    14401 ttcgcgatgg ttgtttactg ttctgtcgtg aacatgtgta ttgaagtttt cctctccgga
    14461 atgagcttcg aacagtcttt ttattccaga ttggtagcga ttccggtgaa catcttaatt
    14521 gcatggccat acggtatgta ccgcgatctg tttatgcgcg cagcacgcaa agttagcccg
    14581 tcgggctgga taaaaaatct ggcggatatc atggcttatg tgacgttcca gtcaccggtg
    14641 tatgtggcga tcttgttagt ggtgggcgca gactggcatc agattatggc ggcagtcagt
    14701 tcaaacatcg ttgtttcgat gttgatgggg gcggtttatg gctacttcct cgattattgc
    14761 cgccgactgt ttaaagtcag ccgttaccag caggtaaaag cctgaccctt cttttcgcga
    14821 ctggcatcgc cagtcgcgtc tttaactggc ttcgccaaat aaaccattca aataacgttc
    14881 aagcgcaaca cgcgaactaa agccatgtgg gataccgtaa tgctcatgac gttcacccgc
    14941 taaatagagc ggaaattgct ggtaatgatc gcaagtttta atatcggaag cgggttcagc
    15001 cagtgttgaa ctacgttctt ttaatgttgg atgaatcacc agggcggtac gtcccattcg
    15061 cgcttcgcga ttaacataga cataattttc cccacggcgg taaccatacg ctttctgggt
    15121 taccacatcg acagtaaaac cgactttttc aagtacgcgc gccacctcgt ctggtcgtaa
    15181 atacatattt gatcctcgtt attatcaacc gcgggcctac cttacctgat tgcgcattca
    15241 caacgctttc agaaaagtcc ataaagccgc gatgaacctc agttaagaaa attatggtct
    15301 acactgaaaa ttacatcgaa ttctaatggg ggatcatatg tttaaccgac cgaaccgcaa
    15361 cgacgttgat gatggcgtgc aggatatcca gaatgatgtc aatcaattag ctgacagtct
    15421 cgaatctgta ttgaagtcct ggggcagcga cgccaaaggg gaagccgaag ccgctcgtag
    15481 taaagcgcag gctctactga aagaaaccag ggcgcggatg catggtcgta ctcgcgtcca
    15541 gcaagccgcg cgcgatgccg ttggctgcgc ggattctttt gttcgtgaaa gaccctggtg
    15601 tagtgtgggt acagcggcag cggtgggtat ttttatcggc gcactgttaa gcatgcgcaa
    15661 atcgtagtgc aaaaatgata ataaatacgc gtctttgacc ccgaagcctg gcttcggggt
    15721 tttttagctt aaggctttac gtaattgttg tgctacctgt cgcgccatac cttcgttaac
    15781 gatattagta aacgaaagca gtaatccacc ttccccactt gaacggatac gccagtcgct
    15841 aagtgcctgc accgcaaggc ctgcagcatt ggctttacgc gcatgggcaa tatcatcgcc
    15901 tatcattctg atcaccatct ggataccacc tttctgcggc acaacctgaa atccttgctg
    15961 cgtcaacgct tgctcaatcc attgccgacg ttgagcataa tgctgacgca ttttcttcag
    16021 atgccgccag aaatgcccct cgcgaagaaa gtctgccagt gtgttctgcc atagaacagg
    16081 taccgcacat ggagccagtg acgcctggtg gcggaattgt gcaatttgct tcaccggcac
    16141 caccagccac gcacagcgca atgcaggaaa tagcgctttg ctgaatgttc cggcataaat
    16201 tacccgctgc ggtgcgtcga gacttttcaa cgccggtaac ggcttaccgt gatagcgaaa
    16261 ctcactgtca taatcatctt caataatcca tgcctgacta cgatctgccc attccagtat
    16321 ctgatgcctg cgcgctaaag agagcgccac acccagcgga ctttggtgtg ctggtgttat
    16381 cagggcaaaa cgcgcatcag gataattttg tattccgctt gtgatatcca gtccattgtc
    16441 atcaaccggc acaggcaaaa tttccacatc atggcgagtg acaatcgggc gaatcagtgg
    16501 aaagccggga tcttctatcc acatcccgtt tcccggtttc gccagcgcgt gcagaattaa
    16561 agctattgag gccgcataac cgtgagtgat aaagacctgc tctggctgac aatcaatccc
    16621 acgtgaaacg cgtaagtaat caactattgc ctcgcgcaac gccgcctcac cgcagacatc
    16681 gcctaacgcc aaatcaaagc gcgtctgggt acgaaggcga cgccccatca cccgcgccca
    16741 cagctctcgc ggaaagagat cgagtgcggg taatcccatt tgaaatggca acggttgctg
    16801 actttcaccg gcaaaagcta caacttgtac agtagattgt tgcggatata tccgctcact
    16861 gacaaatgtg ccagcctgtc cccgcctgat cagccatcct tgcgccacca gctcagcata
    16921 cgcattttcg acagtggaac gagacacccc caactcctgc gaccaggtac gacttgaagg
    16981 cagccttgcg ccgggtttca gttccccttg ctcaatagcc gtttttaact gacgggcgat
    17041 atcctgatag cgcggcatat ggtctgcttt tttaggtaat ttatggctct ctttagcagt
    17101 ccattatagt gctacattgc gggcgttaat aagaggagaa actgtatgac tacattacgt
    17161 cagccttact acgaacttag cccggcagtg tataacgcac tagtgcaggc caaaacggca
    17221 ctggaaaata gcacgctgga taccacgttg atggagttag tttatttgcg cgtctcgcaa
    17281 atcaacggct gcgcattttg tctggagatg cacagcaaag cattgcgcaa atccggcgtg
    17341 ccacagcaca aactggacgc cctggcaggt tggcgcgtaa gccatcattt tgatgaacgc
    17401 gagcgggcgg cgctggcatg ggcggaatcg gtaaccgaaa ttgccagaac ccatgcggaa
    17461 gacgaggttt atcagccttt gcttgagcat ttcagcgcag cagagatcag cgacttaacg
    17521 tttgccatcg ggctgatgaa ttgttttaac cgtctggccg tttccatgcg gatgtaactt
    17581 cttgatgccg ggtattcgcc cggcaaaaaa acacaaaatc ccctaccccg ttgagccatt
    17641 catcggtggc gtaatcaatc taaaattccc atatcttgtg tggttgaatc ttttttcaac
    17701 tacatctagt atctctgtat caacagagag acaacccgac gcgtatcatc gcgccgtatc
    17761 ttcattttaa acggaaatac gaatcatgcg cattactatt tacactcgta acgattgcgt
    17821 tcagtgccac gccaccaaac gggcgatgga aaaccggggc tttgattttg aaatgattaa
    17881 tgtcgatcgc gttcctgaag cggcagaagc gctgcgtgct cagggctttc gtcagttgcc
    17941 ggttgtgatt gcaggcgatc ttagctggtc tggtttccgc ccggacatga tcaatcgtct
    18001 gcatccagcg ccacacgcgg ccagtgcatg agccagctcg tctacttttc cagcagctcc
    18061 gaaaatacgc agcgttttat cgaacgttta gggctgcccg cggtgcgcat cccgctcaat
    18121 gagcgggaac ggattcaggt agacgagcct tacatcctga tcgtgccctc ttacggcggc
    18181 ggcggtacga ctggcgcggt gccacgacag gtcattcgct ttttaaacga cgagcataac
    18241 cgggcgttgc tgcgcggcgt tattgcttcg ggtaatcgca actttggtga ggcatatggc
    18301 cgcgccggag atgtgattgc ccggaaatgc ggcgtgccgt ggctgtaccg ctttgaactc
    18361 atgggtacgc aaagcgatat cgaaaacgtt cgtaaaggag taaccgaatt ttggcaacga
    18421 caaccgcaga acgcctgacg caggaaacga tggattatca cgctctgaat gcgatgctta
    18481 acctttacga tagcgcaggt cgcattcagt tcgataaaga tctccaggca gtagacgcct
    18541 ttatgacgac gcatgtgcgt ccgaacagtg tggccttcag tagccagcag cagcgcctga
    18601 actggctggt taacgaaggt tactatgatg aaagtgtcct taatcgctac tctcgcgatt
    18661 ttgtcattac gctgtttgcc cacgcgcacg ccagcggttt tcgtttccag acattcctcg
    18721 gagcatggaa gttttacacc agctatacgt tgaagacatt cgacggtaag cgttatctgg
    18781 aagattttgc cgatcgcgtc acgatggtgg cgctgacgct ggcacaaggc gatgaaacac
    18841 tggcgacgca gctcactgat gagatgctgt caggacgctt tcagccagcc acgccaacat
    18901 tcctcaactg cggtaagcag cagcgcggcg aactggtttc ctgttttctg ctgcgtattg
    18961 aagacaatat ggagtcgatt ggccgggcag taaattccgc actacaactg tcgaaacgcg
    19021 gcggcggcgt agcatttttg ctgtcgaatc tgcgggaagc gggcgcgcca attaaacgta
    19081 ttgaaaatca atcttctggc gtgattccgg tgatgaaaat gctggaagac gcattttcct
    19141 atgctaacca actcggcgcg cgtcaggggg ctggggcagt ctatttacat gctcatcatc
    19201 ccgatattct gcgttttctc gatacaaaac gggaaaatgc cgacgaaaaa atccgcatta
    19261 aaacactgtc gctgggcgtg gtgatcccgg atatcacttt ccatctggca aaagagaatg
    19321 cgcagatggc gctgttttcg ccttatgacg tagagcgagt ttatggcaaa ccgtttgccg
    19381 atgtcgccat cagcgaacgc tatgacgaac tggttgccga tgaacgcatt cgcaaaaaat
    19441 acctcaacgc ccgtgatttc ttccagcgac tggcagagat ccagtttgag tctggctatc
    19501 cgtacatcat gtatgaagac acggttaacc gtgctaaccc tatcgccggg cgcataaata
    19561 tgagcaatct ctgctcagaa attttgcagg ttaacagcgc ctcagaatat gacgagaatc
    19621 tcgactatgc tcgtacaggc catgatattt cctgcaatct agggtcgttg aatattgccc
    19681 acacaatgga ttcccccgac tttgcccgca cggtagagac tgccgtacgc ggtttaacgg
    19741 cggtgtcaga tatgagtcat atccgcagcg tgccgtccat cgaagccgga aatgccgcct
    19801 cacacgccat cggtctgggg cagatgaatt tacacggtta tctggcgcga gaaggcatcg
    19861 cttatggttc gccggaagca ctggatttca ccaatctcta tttctatacc atcacctggc
    19921 acgcactgcg tacctcgatg ttgctggcgc gcgaacgcgg tgaaaccttc gccgggttca
    19981 aacagtcacg ctatgccagt ggtgaatatt tcagccaata tctgcaaagt aactggcagc
    20041 cgaaaacggc gaaagttggc gaactgtttg cccgtagtgg tattacgtta cctacccgtg
    20101 agatgtgggc gcagctgcgc gacgacgtga tgcgctatgg catatacaac cagaatctcc
    20161 aggcggtgcc gccaaccggt tctatctctt atatcaacca tgccacgtcg agtattcatc
    20221 cgattgtggc gaaagtagag atacgcaaag agggcaaaac aggacgcgtt tactaccctg
    20281 ccccgtttat gactaacgaa aatctggcgc tgtatcagga cgcttacgaa atcggcgcag
    20341 aaaagatcat cgacacctac gcggaagcga ctcgccatgt cgatcagggg ctgtcgctga
    20401 cgctgttttt ccccgatacc gccaccactc gcgatatcaa caaagcgcag atttacgcct
    20461 ggcgcaaagg tatcaaaacg ctctattaca tccgcctgcg tcagatggcg ctggaaggca
    20521 ctgaaattga aggctgcgtc tcctgtgcac tttaaggaat atctatgaaa ctctctcgta
    20581 tcagcgccat caactggaac aagatatctg acgataaaga tctggaggtg tggaatcgcc
    20641 tgaccagcaa tttctggcta ccagaaaagg tgccgctgtc gaacgatatt cctgcatggc
    20701 agacattaag tgtcgtagaa caacaactga cgatgcgcgt ttttactggc ctgacgctgc
    20761 tcgacacgct gcaaaatgtt atcggcgcgc cttcgctgat gcccgatgcg ctcacgcccc
    20821 atgaagaggc ggtattaacg aatatcagct ttatggaagc ggttcatgcc cgctcttaca
    20881 gttcgatttt ctcgacgctg tgccagacca aagatgtcga tgccgcctac gcctggagtg
    20941 aagaaaacgc accgttgcag cgaaaagctc agattattca gcaacattat cgcggggatg
    21001 atccgctgaa aaagaaaatc gccagtgtgt ttcttgaatc ttttttgttc tattccggtt
    21061 tctggctgcc gatgtatttt tccagccgcg gaaagctaac caataccgca gacctgatcc
    21121 gtctgattat ccgcgatgaa gcagtccacg gttattacat cggctataaa tatcagaaaa
    21181 acatggaaaa gatctcccag gcacaacgtg aagagttgaa gagtttcgcc ttcgatttat
    21241 tgctggaact ctacgacaac gagttgcaat acaccgatga gctgtacgcc gaaaccccgt
    21301 gggctgacga tgtgaaagcg tttctctgtt acaacgccaa taaagcgttg atgaatctgg
    21361 gctacgaacc gctatttccc gcagaaatgg cggaagtgaa tccggcaatc ctcgccgcgc
    21421 tttcgccgaa tgccgatgaa aatcacgatt tcttttccgg ttcaggctct tcatatgtga
    21481 tgggaaaagc ggtcgaaaca gaagatgaag actggaattt ctgagggggt tattttcaaa
    21541 aatatcacta cccgctgcag ggaaataatt cccgccaaat agctttatat cacgcaaata
    21601 atttgtggtg atctacactg atactctgtt gcattattcg cctgaaacca caatattcag
    21661 gcgttttttt gctatctttg acaaaaaata tcaacttttc tcgatttgct ctcagccctt
    21721 atatcatggg aaattccggc gatttgctca catcaatatt catgccacat ttgccatcag
    21781 gggttgcctc agattctcag tatgttaggg tagaaaaaag tgactatttc catt
//
LOCUS       DADXDL010000081        21639 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.081, whole genome shotgun sequence.
ACCESSION   DADXDL010000081 DADXDL010000000
VERSION     DADXDL010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21639)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21639)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21639
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.081"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(9..1994)
                     /locus_tag="IRB70_003569"
     CDS             complement(9..1994)
                     /locus_tag="IRB70_003569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBC0633434.1"
                     /translation="MNNSRLFRLSRIVIALTAASGMMVNTAYATDEAKAATQYTQQVN
                     QNYAKSLPFSDRQDFDDAQRGFIAPLLDEGILRDANGKPYYRGEDYKFDINAPAPETV
                     NPSLWRQSQINGISGLFKVTDRMYQVRSQDISNITFIEGDTGIIVIDPLVTPNAAKAS
                     LDLYFKHRPQKPIVAVIYTHSHTDHYGGVKGIVSEADVKAGKVQIIAPAGFMDEAISE
                     NVLAGNIMSRRAFYSYGLLLPHNAQGDIGNGLGVTLTTGGPTIIAPTRSITKTGEKLN
                     IDGLDFEFLMAPGSEAPSEMHLYIPALKALCTAENSTHTLHNFYTLRGAKTRDTAKWT
                     DYLNETLDKWGSQAEVLFMPHTWPVWGNQHINDYIGKYRDTIKYIHDQTLHLANQGYT
                     MNEIGNMIHLPETLDKNWASRGYYGSVSHNARAVYNFYLGYYDGNPANLNPYGQVDMG
                     KRYVKALGGSAHAINLAREAYNQGDYRWASELLKQVIAANPGDQVAKNLQADTFEQLG
                     YQAESATWRGFYLTGAKELREGAKKIEHASTASPDTIKGMTVEMLLDYMAVRLNSEKA
                     AGKSISLNFNLSDNDNLNLSLNNSVLNYRKVLQPKVDASFYMIRSDLHDVLVGQAKMA
                     DLVKAKKAKIIGNGAKLEEIIACLDNFDLWVNIVTPN"
     gene            complement(2267..3196)
                     /gene="alsK"
                     /locus_tag="IRB70_003570"
     CDS             complement(2267..3196)
                     /gene="alsK"
                     /locus_tag="IRB70_003570"
                     /EC_number="2.7.1.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allose kinase"
                     /protein_id="HBC0633435.1"
                     /translation="MQKQHNVVAGVDMGATHIRFCLRTAAGETLHCEKKRTAEVIAPD
                     LVSGIGEMIDEQLRRFNARCRGLVMGFPALVSKDKRTIISTPNLPLTAADLYDLADKL
                     ENTLNCPVEFSRDVNLQLSWDVVENSLTQQLVLAAYLGTGMGFAVWMNGAPWTGAHGV
                     AGELGHIPLGDMTQHCACGNPGCLETNCSGMALRRWYEQQPRNYPLSDLFVHAENASF
                     VQSLLENAARAIATSINLFDPDAVILGGGVMDMPAFPRETLIAMTQKYLRRPLPHQVV
                     RFIAASSSDFNGAQGAAILAHQRFLPQSCAKAP"
     gene            complement(3180..3875)
                     /gene="alsE"
                     /locus_tag="IRB70_003571"
     CDS             complement(3180..3875)
                     /gene="alsE"
                     /locus_tag="IRB70_003571"
                     /EC_number="5.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allulose-6-phosphate 3-epimerase"
                     /protein_id="HBC0633436.1"
                     /translation="MKISPSLMCMDLLKFKEQIEFIDSHADYFHIDIMDGHFVPNLTL
                     SPFFVSQVKKLATKPLDCHLMVTRPQDYIAQLARAGADFITLHPETINGQAFRLIDEI
                     RRHDMKVGLILNPETPVEAMKYYIHKADKITVMTVDPGFAGQPFIPEMLDKLAELKAW
                     REREGLEYEIEVDGSCNQATYEKLMAAGADVFIVGTSGLFNHAENIDEAWRIMTAQIL
                     AAKSEVQPHAKTA"
     gene            complement(3886..4866)
                     /gene="alsC"
                     /locus_tag="IRB70_003572"
     CDS             complement(3886..4866)
                     /gene="alsC"
                     /locus_tag="IRB70_003572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter permease"
                     /protein_id="HBC0633437.1"
                     /translation="MGFTTRVKSEASEKKPFNFALFWDKYGTFFILAIIVAIFGSLSP
                     EYFLTTNNITQIFVQSSVTVLIGMGEFFAILVAGIDLSVGAILALSGMVTAKLMLAGV
                     DPFLAALIGGVLVGGALGAINGCLVNWTGLHPFIITLGTNAIFRGITLVLSDANSVYG
                     FSFDFVNFFAASVIGIPVPVIFSLIVALILWFLTTRMRLGRNIYALGGNKNSAFYSGI
                     DVKFHILVVFIISGVCAGLAGVVSTARLGAAEPLAGMGFETYAIASAIIGGTSFFGGK
                     GRIFSVVIGGLIIGTINNGLNILQVQTYYQLVVMGGLIIAAVALDRLISK"
     gene            complement(4845..6377)
                     /gene="alsA"
                     /locus_tag="IRB70_003573"
     CDS             complement(4845..6377)
                     /gene="alsA"
                     /locus_tag="IRB70_003573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose ABC transporter ATP-binding protein
                     AlsA"
                     /protein_id="HBC0633438.1"
                     /translation="MATPYISMAGIGKSFGPVHALKSVNLTVYPGEIHALLGENGAGK
                     STLMKVLSGIHEPTKGTITINNINYNKLDHKLAAQLGIGIIYQELSVIDELTVLENLY
                     IGRHLTKKICGVNIIDWREMRVRAAIMLLRVGLKVDLDEKVANLSISHKQMLEIAKTL
                     MLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLRKEGTAIVYISHKLAEIRRICDRYTVM
                     KDGSSVCSGMVSDVSNDDIVRLMVGRELQNRFNAMKENVSNLAHDTVFEVRNVTSRDR
                     KKVRDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNDKDISPRSPLD
                     AVKKGMAYITESRRDNGFFPNFSIAQNMAISRSLKDGGYKGAMGLFHEVDEQRTAENQ
                     RELLALKCHSINQNITELSGGNQQKVLISKWLCCHPEVIIFDEPTRGIDVGAKAEIYK
                     VMRQLADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQILTNRDDMSEEEIMAWALP
                     HE"
     gene            complement(6504..7439)
                     /gene="alsB"
                     /locus_tag="IRB70_003574"
     CDS             complement(6504..7439)
                     /gene="alsB"
                     /locus_tag="IRB70_003574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-allose transporter substrate-binding protein"
                     /protein_id="HBC0633439.1"
                     /translation="MNKYLKYFSGTLVGLMLSTSAFAAAEYAVVLKTLSNPFWVDMKK
                     GIEDEAKMLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIAFAPLSSVNLVMPVAR
                     AWKKGIYLVNLDEKIDMDNLKKAGGNVEGFVTTDNVAVGAKGASFIIDKLGAEGGEVA
                     IIEGKAGNASGEARRNGATEAFKKASQIKLVASQPADWDRIKALDVATNVLQRNPNIK
                     AIYCANDTMAMGVAQAVANAGKTGKVLVVGTDGIPEARKMVEAGQMTATVAQNPADIG
                     ATGLKLMVDAEKSGKVIPLDKAPEFKLVDSILVTQ"
     gene            complement(7498..8388)
                     /gene="alsR"
                     /locus_tag="IRB70_003575"
                     /gene_synonym="rpiR"
     CDS             complement(7498..8388)
                     /gene="alsR"
                     /locus_tag="IRB70_003575"
                     /gene_synonym="rpiR"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418513.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="als operon DNA-binding transcriptional repressor
                     AlsR"
                     /protein_id="HBC0633440.1"
                     /translation="MSQSEFDSALPNGIGLAPYLRMKQEGMTENESRIVEWLLKPGNL
                     SCAPAIKDVAEALAVSEAMIVKVSKLLGFSGFRNLRSALEDYFSQSEQVLPSELAFDE
                     APQDVVNKVFNITLRTIMEGQSIVNVDEIHRAARFFYQARQRDLYGAGGSNAICADVQ
                     HKFLRIGVRCQAYPDAHIMMMSASLLQEGDVVLVVTHSGRTSDVKAAVELAKKNGAKI
                     ICITHSYHSPIAKLADYIICSPAPETPLLGRNASARILQLTLLDAFFVSVAQLNIEQA
                     NINMQKTGAIVDFFSPGALK"
     gene            8747..9196
                     /gene="rpiB"
                     /locus_tag="IRB70_003576"
     CDS             8747..9196
                     /gene="rpiB"
                     /locus_tag="IRB70_003576"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional allose-6-phosphate
                     isomerase/ribose-5-phosphate isomerase RpiB"
                     /protein_id="HBC0633441.1"
                     /translation="MKKIAFGCDHVGFILKHEIVAHLVERGVEVIDKGTWSSERTDYP
                     HYASQVALAVAGGEADGGILICGTGVGISIAANKFAGIRAVVCSEPYSAQLSRQHNDT
                     NVLAFGSRVVGLELAKMIVDAWLGAQYEGGRHQQRVEAITEIEQRRN"
     gene            9265..9594
                     /gene="yjdP"
                     /locus_tag="IRB70_003577"
     CDS             9265..9594
                     /gene="yjdP"
                     /locus_tag="IRB70_003577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein YjdP"
                     /protein_id="HBC0633442.1"
                     /translation="MKRFPLFLLFTLFTLSTVPAQADIIDDTIGNIQQAINDAYNPDR
                     GRDYEDSRDDGWQREVNDDRRRQYDDRRRQFEDRRRQLDDRQRQLDQERRQLEDEERR
                     MEDEYGR"
     gene            complement(9629..10387)
                     /gene="phnP"
                     /locus_tag="IRB70_003578"
     CDS             complement(9629..10387)
                     /gene="phnP"
                     /locus_tag="IRB70_003578"
                     /EC_number="3.1.4.55"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism protein PhnP"
                     /protein_id="HBC0633443.1"
                     /translation="MSLTLTLTGTGGAQGVPAWGCECVACARARRSPQYRRQPCSGVV
                     KFNDAITLIDAGLHDLADRWSPGSFQQFLLTHYHMDHVQGLFPLRWGVGDQIPVYGPP
                     DEQGCDDLFKHPGLLDFSHTMEPFVVFELQGLQVTPLPLNHSKLTFGYLLETAHSRVA
                     WLSDTAGLPEKTLKFLRNNQPQVMVIDCSHPPREDAPRNHCDLNTVLALNQVIRSPRV
                     ILTHISHQFDAWLMENALPSGFEAGFDGMVIGVE"
     gene            complement(10389..10823)
                     /gene="phnO"
                     /locus_tag="IRB70_003579"
     CDS             complement(10389..10823)
                     /gene="phnO"
                     /locus_tag="IRB70_003579"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoalkylphosphonate N-acetyltransferase"
                     /protein_id="HBC0633444.1"
                     /translation="MPACELRPATQYDTDAVYALICELKQAEFDHHAFRVGFNANLRD
                     PNMRYHLALLDGEVVGMIGLHLQFHLHHVNWIGEIQELVVMPQARGLNIGSKLLAWAE
                     EEARQAGAEMTELSTNVKRHDAHRFYLREGYEQSHFRFTKAL"
     gene            complement(10810..11367)
                     /gene="phnN"
                     /locus_tag="IRB70_003580"
     CDS             complement(10810..11367)
                     /gene="phnN"
                     /locus_tag="IRB70_003580"
                     /EC_number="2.7.4.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose 1,5-bisphosphokinase"
                     /protein_id="HBC0633445.1"
                     /translation="MTGKLIWLMGASGSGKDSLLTELRQREQTQLLVAHRYITRAASA
                     GSENHIALSEQEFFTRAGQNLLALSWHANGLYYGVGVEIDLWLHAGFDVVVNGSRAHL
                     PQARARYQSALLPVCLQVSPEILRQRLENRGRENASEINARLARAARYTPQDCLTLNN
                     DGSLRQSVDKLLTLIHQKEKHHACL"
     gene            complement(11367..12503)
                     /gene="phnM"
                     /locus_tag="IRB70_003581"
     CDS             complement(11367..12503)
                     /gene="phnM"
                     /locus_tag="IRB70_003581"
                     /EC_number="3.6.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate diphosphatase"
                     /protein_id="HBC0633446.1"
                     /translation="MIINNVKLVLENEVVHGSLEVQDGEIRAFAESQSCQPEAMDGEG
                     GWLLPGLIELHTDNLDKFFTPRPKVDWPAHSAMSSHDALMVASGITTVLDAVAIGDVR
                     DGGDRLENLEKMINAIEETQKRGVNRAEHRLHLRCELPHHTTLPLFEKLVQREPVTLV
                     SLMDHSPGQRQFANREKYREYYQGKYSLTDAQMQQYEEEQLALAARWSQPNRETIAAM
                     CRARHIALASHDDATHAHVAESHQLGSVIAEFPTTFEAAEASRKHGMNVLMGAPNIVR
                     GGSHSGNVAASELAQLGLLDILSSDYYPASLLDAAFRVADDESNRFTLPQAVKLVTKN
                     PAQALNLQDRGVIGEGKRADLVLAHRKGNHIHIDHVWRQGKRVF"
     gene            complement(12500..13180)
                     /gene="phnL"
                     /locus_tag="IRB70_003582"
     CDS             complement(12500..13180)
                     /gene="phnL"
                     /locus_tag="IRB70_003582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnL"
                     /protein_id="HBC0633447.1"
                     /translation="MINVQNVSKTFILHQQNGVRLPVLQRASLTVNAGECVVLHGHSG
                     SGKSTLLRSLYANYLPDEGQIQIKHGEEWVDLVTAPARKVVEIRKTTIGWVSQFLRVI
                     PRISALEVVMQPLLDTGVPREACAAKAARLLTRLNVPERLWHLAPSTFSGGEQQRVNI
                     ARGFIVDYPILLLDEPTASLDAKNSAAVVELIREAKARGAAIVGIFHDEAIRNDVADR
                     LHPMGVSS"
     gene            complement(13291..14049)
                     /gene="phnK"
                     /locus_tag="IRB70_003583"
     CDS             complement(13291..14049)
                     /gene="phnK"
                     /locus_tag="IRB70_003583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnK"
                     /protein_id="HBC0633448.1"
                     /translation="MNQPLLSVNNLTHLYAPGKGFSDVSFDLWPGEVLGIVGESGSGK
                     TTLLKSISARLTPQQGEIRYENRSLYGMSEADRRRLLRTEWGVVHQHPLDGLRRQVSA
                     GGNIGERLMATGARHYGDIRATAQKWLEEVEIPANRIDDLPTTFSGGMQQRLQIARNL
                     VTHPKLVFMDEPTGGLDVSVQARLLDLLRGLVVELNLAVVIVTHDLGVARLLADRLLV
                     MKQGQVVESGLTDRVLDDPHHPYTQLLVSSVLQN"
     gene            complement(14046..14891)
                     /gene="phnJ"
                     /locus_tag="IRB70_003584"
     CDS             complement(14046..14891)
                     /gene="phnJ"
                     /locus_tag="IRB70_003584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate 5-phosphate
                     C-P-lyase PhnJ"
                     /protein_id="HBC0633449.1"
                     /translation="MANLSGYNFAYLDEQTKRMIRRAILKAVAIPGYQVPFGGREMPM
                     PYGWGTGGIQLTASVIGESDVLKVIDQGADDTTNAVSIRNFFKRVTGVNTTERTDDAT
                     LIQTRHRIPETPLTEDQIIIFQVPIPEPLRFIEPRETETRTMHALEEYGVMQVKLYED
                     IARFGHIATTYAYPVKVNGRYVMDPSPIPKFDNPKMDMMPALQLFGAGREKRIYAVPP
                     FTRVESLDFDDHPFTVQQWDEPCAICGSTHSYLDEVVLDDAGNRMFVCSDTDYCRQQS
                     EAKNQ"
     gene            complement(14884..15948)
                     /gene="phnI"
                     /locus_tag="IRB70_003585"
     CDS             complement(14884..15948)
                     /gene="phnI"
                     /locus_tag="IRB70_003585"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-ribose 1-methylphosphonate
                     5-triphosphate synthase subunit PhnI"
                     /protein_id="HBC0633450.1"
                     /translation="MYVAVKGGEKAIDAAHALQESRRRGNTDLPELSVAQIEQQLNLA
                     VDRVMTEGGIADRELAALALKQASGDNVEAIFLLRAYRTTLAKLAVSEPLDTTEMRLE
                     RRISAVYKDIPGGQLLGPTYDYTHRLLDFTLLANGEAPTLTTADSEQQPSPHVFSLLA
                     RQGLAKFEEDSGAQPDDITRTPPVYPCSRSSRLQQLMRGDEGYLLALAYSTQRGYGRN
                     HPFAGEIRSGYIDVSIVPEELGFAVNVGELLMTECEMVNGFIDPPDEPPHFTRGYGLV
                     FGMSERKAMAMALVDRALQAPEYGEHATGPAQDEEFVLAHADNVEAAGFVSHLKLPHY
                     VDFQAELELLKRLQQEQNHG"
     gene            complement(15948..16532)
                     /gene="phnH"
                     /locus_tag="IRB70_003586"
     CDS             complement(15948..16532)
                     /gene="phnH"
                     /locus_tag="IRB70_003586"
                     /EC_number="2.7.8.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnH"
                     /protein_id="HBC0633451.1"
                     /translation="MTLETAFMLPVQDAQHSFRRLLKAMSEPGVIVALHQLKRGWQPL
                     NIATTSVLLTLADNDTPVWLSAPLSNDIVSQSLRFHTNAPLVNQPELATFAVTDEAIS
                     SEQLNALSSGTAVAPEAGATLILQVVSLSGGRMLRLTGAGIAEERMIAPQLPECILHE
                     LTERPHPFPLGIDLILTCGERLLAIPRTTHVEVC"
     gene            complement(16529..16981)
                     /gene="phnG"
                     /locus_tag="IRB70_003587"
     CDS             complement(16529..16981)
                     /gene="phnG"
                     /locus_tag="IRB70_003587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate C-P lyase system protein PhnG"
                     /protein_id="HBC0633452.1"
                     /translation="MHADTATRQHWMSVLAHSQPTELAARLNALNITADYEVIRAAET
                     GLVQIQARMGGTGERFFAGDATLTRAAVRLTDGTLGYSWVLGRDKQHAERCALIDALM
                     QQTRHFQNLSETLIAPLNADRMARIAARQAEVNASRVDFFTMVRGDNA"
     gene            complement(16982..17707)
                     /gene="phnF"
                     /locus_tag="IRB70_003588"
     CDS             complement(16982..17707)
                     /gene="phnF"
                     /locus_tag="IRB70_003588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate metabolism transcriptional regulator
                     PhnF"
                     /protein_id="HBC0633453.1"
                     /translation="MHLSTHPTSYPTRYQEIAAKLEQELRQHYRCGDYLPAEQQLAAR
                     FEVNRHTLRRAIDQLVEKGWVQRRQGVGVLVLMRPFDYPLNAQARFSQNLLDQGSHPT
                     SEKLLSVLRPASGHVADALGITEGENVIHLRTLRRVNGVALCLIDHYFADLTLWPTLQ
                     RFDSGSLHDFLREQTGIALRRSQTRISARRAQAKECQRLEIPNMSPLLCVRTLNHRDG
                     ESSPAEYSVSLTRADMIEFTMEH"
     gene            complement(17728..18507)
                     /gene="phnE"
                     /locus_tag="IRB70_003589"
     CDS             complement(17728..18507)
                     /gene="phnE"
                     /locus_tag="IRB70_003589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313113.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter, permease protein
                     PhnE"
                     /protein_id="HBC0633454.1"
                     /translation="MQTITIAPPKRSWFSLLSWAIVLAVLVVSWQGAEMAPLTLIKDG
                     GNMATFAADFFPPDFSQWQDYLTEMAVTLQIAVWGTALAVVLSIPFGLMSAENLVPWW
                     VYQPVRRLMDACRAINEMVFAMLFVVAVGLGPFAGVLALFIHTTGVLSKLLSEAVEAI
                     EPGPVEGIRATGANKLEEILYGVLPQVMPLLISYSLYRFESNVRSATVVGMVGAGGIG
                     VTLWEAIRGFQFQQTCALMVLIIVTVSLLDFLSQRLRKHFI"
     gene            complement(18572..19588)
                     /gene="phnD"
                     /locus_tag="IRB70_003590"
     CDS             complement(18572..19588)
                     /gene="phnD"
                     /locus_tag="IRB70_003590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBC0633455.1"
                     /translation="MNAKIIASLAFTSMFSLSTLLSPAHAEEQEKALNFGIISTESQQ
                     NLKPQWTPFLQDMEKKLGVKVNAFFAPDYAGIIQGMRFNKVDIAWYGNLSAMEAVDRA
                     NGQVFAQTVAADGSPGYWSVLIVNKDSPINNLNDLLAKRKDLTFGNGDPNSTSGFLVP
                     GYYVFAKNNISASDFKRTVNAGHETNALAVANKQVDVATNNTENLDKLKTSAPEKLKE
                     LKVIRKSPLIPGDPIVWRKNLSETTKDKIYDFFMNYGKTPEEKAVLERLGWAPFRASS
                     DLQLVPIRQLALFKEMQGVKGNKGLNEQDKLAKTTAIQAQLDDLDRLNNALSAMSSVS
                     KAVQ"
     gene            complement(19613..20401)
                     /gene="phnC"
                     /locus_tag="IRB70_003591"
     CDS             complement(19613..20401)
                     /gene="phnC"
                     /locus_tag="IRB70_003591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonate ABC transporter ATP-binding protein"
                     /protein_id="HBC0633456.1"
                     /translation="MQTIIRVEKLAKTFNQHQALHAVDLNIHHGEMVALLGPSGSGKS
                     TLLRHLSGLITGDKSAGSHIELLGRTVQREGRLARDIRKSRANTGYIFQQFNLVNRLS
                     VLENVLIGALGSTPFWRTCFSYFTREQKQRALQALTRVGMVHFAHQRVSTLSGGQQQR
                     VAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALR
                     YCERIVALRQGHVFYDGSSQQFDNERFDHLYRSINRVEENAKAA"
     gene            complement(20534..20977)
                     /gene="yjdN"
                     /locus_tag="IRB70_003592"
     CDS             complement(20534..20977)
                     /gene="yjdN"
                     /locus_tag="IRB70_003592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family metalloprotein YjdN"
                     /protein_id="HBC0633457.1"
                     /translation="MPLSPYLSFAGNCADAIAYYQRTLGAELLYKISFGEMPKSAQDS
                     AENCPSGMQFPDTAIAHANVRIAGSDIMMSDAIPSGKASYSGFTLVLDSQQVEEGKRW
                     FDNLAANGKIEMAWQETFWAHGFGKVTDKFGVPWMINVVKQQPTQ"
     gene            complement(21137..21472)
                     /locus_tag="IRB70_003593"
     CDS             complement(21137..21472)
                     /locus_tag="IRB70_003593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phnA family protein"
                     /protein_id="HBC0633458.1"
                     /translation="MSLPHCPKCNSEYTYEDNGMYICPECAYEWNDAEPAQESDELIV
                     KDANGNLLADGDSVTIIKDLKVKGSSSMLKIGTKVKNIRLVEGDHNIDCKIDGFGPMK
                     LKSEFVKKN"
BASE COUNT         4680 a         5780 c         6001 g         5178 t
ORIGIN      
        1 gagtggcatt aatttggggt tacgatattc acccacaaat cgaaattatc cagacaggca
       61 ataatttctt ccagttttgc gccattgcca ataattttgg ctttcttcgc ctttaccaga
      121 tccgccattt tggcttgtcc gaccagcacg tcgtgcagat cgctgcggat catgtaaaac
      181 gatgcgtcta ccttcggttg cagtacttta cggtagttca atacgctatt gttgagtgag
      241 aggttcaggt tatcgttgtc agagagattg aagttcaggc tgatggattt gcccgcggct
      301 ttctcactgt tcagacgaac agccatgtaa tcaagcagca tctcgacggt catacccttg
      361 atggtgtcag gagaggcggt gctggcgtgt tcgattttct tcgcgccctc acgcagttct
      421 ttcgctcccg tcaggtagaa gccgcgccag gtggctgatt cggcctgata acccaattgt
      481 tcgaaggtat cggcctgtag gtttttcgcc acctggtctc ccggattggc agcaatcacc
      541 tgtttcagca gttcagaggc ccagcggtag tcgccctggt tataggcttc acgcgccaga
      601 ttgatagcat gtgcggaacc tcccagcgct ttgacataac gtttacccat atcgacctgg
      661 ccatacggat tcaggtttgc tgggttaccg tcgtagtagc cgaggtaaaa gttatatacc
      721 gcgcgagcgt tatgactgac ggagccataa tagccacggc tggcccagtt tttatccagc
      781 gtttccggca gatgaatcat gttgccgatt tcattcatgg tgtaaccctg gttcgccagg
      841 tgcagggtct ggtcgtgaat atacttaatg gtgtcgcgat attttccaat ataatcattg
      901 atatgttgat taccccatac tggccaggta tgtggcataa acagcacttc tgcttgtgat
      961 ccccacttat ccagcgtttc attcaggtaa tcggtccact tcgcggtatc acgggttttc
     1021 gcgccacgca gggtgtagaa gttatgcagg gtatgggtgc tgttttccgc tgtgcacagg
     1081 gctttcaacg ccggaatata gaggtgcatt tcagacggcg cttcgctgcc tggagccatc
     1141 agaaattcga aatccagccc gtcgatattg agtttctctc ctgtcttggt gatagatcgc
     1201 gtcggcgcga taattgtcgg gccgccggta gtaagcgtaa cacccagccc gttgccgata
     1261 tctccctgtg cattatgcgg gagtagcagg ccgtaagagt aaaatgcacg gcgactcatg
     1321 atattacccg ccagcacgtt ttcactgatg gcttcgtcca taaagcctgc cggggcgatg
     1381 atctgcactt tgcctgcttt tacatcggct tctgagacaa taccttttac gccgccatag
     1441 tggtcagtgt ggctgtgggt gtagataacg gccacaatcg gtttttgtgg gcggtgtttg
     1501 aaatagagat caaggctggc ttttgctgca tttggcgtca ccagcgggtc aatgacgatg
     1561 atgcccgtat caccttcaat gaaggtgatg ttcgagatat cctggctgcg cacctgatac
     1621 atgcggtcgg tgactttaaa caggccagaa atgccgttga tctgcgactg acgccacagg
     1681 cttgggttaa cggtttcggg cgcgggcgca ttgatatcaa atttataatc ttctccgcga
     1741 taatatggtt tgccattagc atcgcgcaga ataccttcat ccagcagcgg agcgataaat
     1801 ccacgctgag catcgtcaaa atcctgacga tcgctaaacg gtaatgattt ggcgtaattc
     1861 tgattaacct gttgggtata ttgagtggcg gctttcgctt catctgttgc gtaagcggta
     1921 tttaccatca tgccgctggc ggcagttaac gcaataacaa tcctgctcaa acggaataac
     1981 cgagagttat tcatataaat ctccatttat catttatgtc gtaaatatgt aatccatgca
     2041 aaatacgtca tttgaagctg gcgttatcat aattgggaat ttgcgatttt aataagtgga
     2101 agtgtgagcg gaacgcgcca ttttattagg catttgtgct gaagagggga aattccagta
     2161 gaactatcat tgctgaaaat aatatgagct gttttatgtg tttattatat atattgtact
     2221 tgtcgttggc acagcgggac attgcgttac tgtgccaacg ctttactcat ggggctttag
     2281 cacaggactg tggcaaaaaa cgttgatgtg ccaatattgc tgcaccctga gcgccattaa
     2341 agtcagaaga tgaggcggca ataaagcgca cgacctgatg cggcagtgga cggcgcaggt
     2401 atttttgggt catggcaatg agagtctcgc gtgggaaggc gggcatatcc atcacgccac
     2461 cgcccagaat caccgcatcg ggatcgaaca gattaatgct ggtggcaatg gcccgagccg
     2521 cgttttcaag cagactctgg acgaaagagg cgttttccgc atggacgaaa agatcgctca
     2581 atgggtaatt tcggggctgt tgttcgtacc agcgtcttag cgccattcca gagcaattgg
     2641 tttccaggca cccaggattg ccacacgcgc aatgttgggt catatctccc agggggatat
     2701 ggcccagttc gcctgccaca ccgtgtgcac ccgtccacgg cgcaccgttc atccacactg
     2761 cgaaccccat ccccgtaccg agataggccg ccagaaccag ttgttgcgta aggctgtttt
     2821 ctactacgtc ccaggagagt tgcaggttaa cgtcgcggga aaactcaacc ggacaattca
     2881 gcgtattttc gagcttatcg gcgagatcat ataaatccgc cgctgttaac ggcaggttag
     2941 gcgtagaaat aatggtgcgt ttatctttac tgaccagcgc cggaaatccc atcaccagac
     3001 cacgacagcg agcgttaaag cgcctgagtt gctcgtcaat catttcgccg atacccgaca
     3061 ccaggtcggg agcaataact tctgcggtcc gctttttttc gcagtgtagc gtttcacctg
     3121 ctgctgtccg cagacaaaag cggatatgcg ttgcccccat atccacgccc gctacgacgt
     3181 tatgctgttt ttgcatgagg ctgtacctcg ctttttgcag ccagaatctg cgcggtcata
     3241 attctccatg cttcgtcgat attttccgca tgattaaaca ggccggaagt gccgacgata
     3301 aagacatccg cccctgccgc cattagtttt tcgtaagttg cctggttgca ggaaccgtcc
     3361 acctcaattt cgtactccag accttctcgt tcacgccatg ccttcagttc ggcaagttta
     3421 tccagcattt caggaatgaa cggttgtccg gcaaagccgg gatcgacagt catgaccgta
     3481 attttatcgg ccttatggat atagtatttc atggcctcaa ctggcgtctc cgggttaagg
     3541 attagcccca ctttcatgtc atgacggcgg atttcatcaa tcaggcggaa cgcctggccg
     3601 ttgatggttt ccggatgcag agtgataaaa tcggctcccg cacgcgccag ttgcgcaatg
     3661 taatcctgcg gccgcgtcac catcagatga cagtcgagcg gtttagttgc cagtttttta
     3721 acctgactta cgaagaacgg tgagagtgtc agattgggga caaagtgacc gtccatgata
     3781 tcgatgtgaa agtaatcggc atggctgtcg ataaattcga tctgttcttt aaatttcagc
     3841 aaatccatac acattaacga gggggagatt ttcatgttca attccttact tactgataag
     3901 acggtcaagg gcgacagccg cgataattaa tccgcccatc accaccagtt ggtaataggt
     3961 ttgtacctgc aaaatattca gaccgttgtt gatggtgccg atgatcaacc cgccaatcac
     4021 cacagagaaa atgcgcccct tgccgccgaa gaaactggtg ccgccaatga tggcgctggc
     4081 aatggcatag gtttcaaaac ccataccggc aagcggttct gcggcaccga gtcgtgcagt
     4141 tgagacgacg cctgccagac ctgcacaaac accggagatg ataaacacca ccaggatgtg
     4201 gaatttcacg tcaatcccgg aatagaacgc cgagtttttg ttgccgccca gtgcgtagat
     4261 gttgcgtccg agccgcatac gcgttgtcag aaaccaaagg atgagcgcga caattagcga
     4321 gaagataacg ggaacaggta tcccaattac gctggcggca aagaagttca cgaagtcaaa
     4381 tgagaagccg tataccgagt tggcatcgga gagcaccagc gtgatcccac ggaaaatagc
     4441 gttggtacca agggtgataa taaatgggtg tagccccgtc cagttgacca ggcagccgtt
     4501 gatcgccccc agtgcgccgc caaccagtac accgccaatc agcgccgcga gaaacgggtc
     4561 aacacctgcc aacatcagtt tggcggtcac cataccggaa agcgccagaa tcgcgccaac
     4621 cgagaggtcg ataccagcga ccaggatagc gaaaaactcg cccatgccga tcaataccgt
     4681 cacggagctt tgcacaaaaa tctgggtaat attattggtg gtcagaaaat attctggtga
     4741 cagcgaacca aagatggcga cgatgatcgc caggataaaa aaggtgccgt atttatccca
     4801 gaacagcgca aagttgaacg gtttcttctc gctcgcttcg ctttttactc gtgtggtaaa
     4861 gcccatgcca taatctcctc ttcgctcatg tcatcgcgat tcgtcaggat ttgcgtcagt
     4921 cgtccttcgc agaacacggc gatgcggtcg cagacggtga taatttcagg tagttcagat
     4981 gacaccatca ggatgacttt tccgtcgtcc gccagttggc gcatcacttt gtaaatttcg
     5041 gctttcgcgc caacgtcgat gccgcgggta ggttcatcga aaatgatcac ttccgggtga
     5101 cagcacagcc atttggagat caggactttc tgctgattcc ccccggagag ttcggtgata
     5161 ttctggttta tcgaatgaca tttcagcgcc agcagttcgc gttgattttc agcggtacgt
     5221 tgctcgtcaa cttcatgaaa caagcccatc gcgcctttat agccgccgtc tttcagactg
     5281 cggctgatcg ccatgttctg agcgatggaa aagttgggga aaaaaccgtt atcccggcgg
     5341 ctttcagtga tgtaagccat cccttttttc acggcatcca ggggtgagcg tggagagata
     5401 tctttgtcat taagacggat ttctccgcca gcgcgtttat caacgccaaa caggcagttc
     5461 atcagttcag tacgtccgga accgaccagt ccggcaaagc ctaatatttc tccccggcag
     5521 acgctaaatg agatatcccg gacctttttt ctgtcacggc tggtgacgtt gcgcacctca
     5581 aaaaccgtat cgtgcgcaag gttgctgaca ttctccttca tcgcgttaaa acggttttgc
     5641 agttcgcggc ctaccatcag acggacgata tcgtcatttg acacatcgct caccatgccg
     5701 ctgcaaacgc tgctgccgtc tttcatcacc gtatagcggt cgcaaatacg gcgaatttcc
     5761 gccaacttat gcgagatata gacgatggcc gtaccctctt tacgcaactg attcatgatc
     5821 agaaacagat agtccacctc tttattggtg agtgaggagg tgggttcatc catgatgatg
     5881 actttggcgt cgagcatcag cgttttggca atttccagca tctgcttgtg gctgatagat
     5941 aagttcgcca ctttctcatc taaatcaact ttcaagccca cgcgtaataa cattatggcg
     6001 gcgcggacac gcatttctcg ccagtcgata atattgacgc cacagatttt tttcgtcaga
     6061 tgacgaccaa tatataaatt ttccagtacg gttaattcat caataacgct gagttcctga
     6121 taaatgatcc cgataccgag ttgtgccgct aatttatgat ccagcttgtt atagttaatg
     6181 ttattaatgg taatggtgcc tttggttggc tcatgtattc cggataacac tttcattagc
     6241 gtggatttac ccgcgccatt ttctcctagt aatgcatgta tttcaccagg ataaaccgtt
     6301 aaattaaccg actttaatgc gtgaaccgga ccaaaggact tgccgatccc cgccatcgat
     6361 atatatggcg tggccataaa taacctctct gcacgaaata tcgtattatt gcctgatggc
     6421 tacgtttatc aggtctacgt tcaggttatt ttgttggccg gataagacac ttcattagca
     6481 tcatcatccg gcatcattca gttttattga gtgaccagga ttgaatcgac cagtttaaat
     6541 tccggtgctt tatccagcgg gataaccttg ccggatttct cagcgtcaac catcagcttc
     6601 agacccgttg caccgatatc cgccgggttc tgggcaaccg tcgcggtcat ttgtccggct
     6661 tccaccattt tgcgggcttc cggaattcca tctgtaccga cgaccaacac tttgcccgtt
     6721 tttccggcgt ttgcgactgc ctgagcaaca cccattgcca tcgtgtcatt cgcgcaatag
     6781 atcgctttaa tattcggatt acgttgcaac acgttagtgg cgacatccag tgctttaata
     6841 cggtcccagt cggcaggctg gctggcgaca agcttgatct ggcttgcttt tttgaaggct
     6901 tcggtggcac cattacgacg cgcttcaccg gaggcgttac cggctttacc ctcaatgatt
     6961 gcgacttcac ccccttcggc acccagcttg tcaataatga atgacgcgcc tttcgccccg
     7021 acggcaacat tatcggtggt gacaaaacct tccacattac cgcctgcttt tttcagatta
     7081 tccatgtcga ttttttcatc gagattgacc agataaatgc cttttttcca tgcgcgggcg
     7141 acaggcatga ccagatttac tgaggataat ggcgcgaagg cgataccttt gtaattttta
     7201 ttactgagat cttcaaataa ctgcaattga gattgaaaat caccttctga aggagaggca
     7261 aaaatatcaa cgctgacgcc cagcattttt gcttcatctt caatgccttt tttcatatct
     7321 acccaaaatg ggttggagag tgttttcaat acgacggcat attcggcggc agcaaaagcg
     7381 ctggttgaca acattaagcc cacgagtgtg ccgctgaaat atttcagata tttattcata
     7441 atcatgttct cacggtaagg ggagaggtaa ctccgcgatg gcggaattac ctttttctta
     7501 tttcagcgcg cctggtgaga agaaatcaac aattgcgccg gttttttgca tattaatatt
     7561 agcttgttca atgttgagct gggcgacaga gacaaaaaac gcgtccagca aagttagttg
     7621 taatattctt gccgaggcat tacgacctaa taacggtgtt tccggggccg gtgagcaaat
     7681 aatataatcg gccagcttcg ctatcggtga atggtagcta tgcgttatac aaataatctt
     7741 tgccccgttc ttttttgcca gttctacagc cgcttttaca tcactggttc gcccggaatg
     7801 ggtcaccacc agcaccacat ctccttcctg taacaacgaa gcagacatca tcatgatgtg
     7861 agcgtccgga taggcctggc agcgtacgcc aatgcgtaaa aacttgtgct gtacatcagc
     7921 acagatagca tttgatcctc cggcaccgta caaatcccgc tgcctggcct gatagaaaaa
     7981 gcgggcggca cggtggatct catcaacgtt gacgatcgac tgaccttcca taatggtgcg
     8041 taaagtgatg ttaaatacct tattcaccac atcctgcggc gcttcatcaa aagccaactc
     8101 ggaaggcaat acttgttctg actgagaaaa ataatcttcc agcgcactgc gtaagttacg
     8161 aaagccgcta aaccccagca gctttgatac cttaacgatc atcgcttcag ataccgccag
     8221 agcttctgcg acatctttaa ttgcgggtgc acaactcagg ttaccgggtt tgagtaacca
     8281 ctccacgatg cggctttcgt tttctgtcat tccttcctgc ttcattcgca ggtaaggcgc
     8341 taacccgata ccgttcggaa gcgctgaatc aaactctgac tggctcatca cgttctcttg
     8401 tccttgaatt gaagacgcca ctatatcacc acagcaagaa cagaaaagat gctggcaact
     8461 tcacaaaaaa ataaaattta taaagtttgt tttgttgtga ataatggaga gtggcttaaa
     8521 attccatttc atttaatcac tttaaaaaca tgatgttatt tgtttttctg gtttattgga
     8581 tgatagatat tgctggatag tgagtgtctt taacgctatt gcgctgccag atgtaactct
     8641 gtaaaacaga tcgggaaggc ggatttcatc gattttgggt gtttttaatt catttacatc
     8701 acaaatgttt tttgattgtg aagttttgca cgggcgggga agatgaatga aaaagattgc
     8761 atttggctgt gatcatgtcg gtttcatttt aaaacatgaa atagtggcac atttagttga
     8821 gcgtggcgtc gaagtgattg ataaaggaac ctggtcgtca gagcgtactg attatccgca
     8881 ttacgccagt caagtcgcac tggcagttgc tggcggagag gctgatggcg ggattttgat
     8941 ttgtggcact ggcgtcggta tttcgatagc ggcgaacaag tttgccggaa ttcgcgcggt
     9001 cgtttgtagc gaaccttatt ccgcgcaact ttcgcggcag cataacgaca ccaacgtgct
     9061 ggcttttggt tcaagagtgg ttggcctcga actggcaaaa atgattgtcg atgcgtggct
     9121 gggcgcacag tacgaaggcg gtcgtcatca acaacgcgtg gaggcgatta cggaaataga
     9181 gcagcggaga aattgagatt catccactac ttgcatggat gagtaatgac taatgtggat
     9241 agagtttctt tttgaggttg gctaatgaaa cgctttccgc tatttctttt attcaccctg
     9301 ttcacgctgt ccaccgttcc ggcccaggcc gatattatcg atgacaccat tggcaatatt
     9361 cagcaggcga ttaacgacgc ttataaccct gatcgtgggc gagactatga agattcgcgc
     9421 gacgacggct ggcagcgtga agtgaacgac gatcggcgca gacaatatga cgatcgccgc
     9481 cgccagtttg aagatcgccg caggcagctg gacgatcgcc agcgccagct ggatcaggag
     9541 cgtcggcagc tagaagatga agagcggaga atggaagatg agtatgggcg gtgatgttga
     9601 gtctagagca ggcatcgccc ctcacccatc actccacccc aatcaccatc ccatcaaaac
     9661 ccgcctcaaa ccccgacggc agtgcgtttt ccatcagcca cgcatcaaac tggtggctga
     9721 tatgggtcag aatcacccgt ggcgagcgga taacctgatt cagcgcaagc acggtattta
     9781 aatcacagtg attacgcggt gcatcctcgc gcggcgggtg gctgcaatca atcaccatta
     9841 cctgcggctg attattgcgt aaaaatttca gcgttttttc cggcaagcca gcggtgtcag
     9901 acagccacgc cacccggctg tgtgccgttt ccagcagata accgaaggtc agttttgagt
     9961 ggttgagcgg cagcggcgtg acctgtaacc cctgtaattc aaacaccaca aacggttcca
    10021 tcgtgtggct gaaatcaagc aggcccggat gtttaaacag atcgtcgcag ccctgttcat
    10081 ccggcgggcc gtagaccggg atctgatcgc ccacgcccca gcgcagcgga aacagcccct
    10141 ggacgtgatc catatgataa tgcgtcagca aaaactgctg gaacgatcct ggcgaccagc
    10201 gatcggcgag atcgtgcagc ccggcgtcga tcagggtgat tgcgtcgtta aactttacta
    10261 cgccgctgca tggctggcgg cgatactgcg gcgagcgtcg tgctctggcg caggccacgc
    10321 actcacagcc ccatgcggga acgccctgtg cgccgccagt gccagtaagc gtgagggtca
    10381 ggctcatgtt acagcgcctt ggtgaagcgg aagtggctct gctcgtagcc ttcgcgcaga
    10441 tagaaacggt gcgcgtcgtg gcgcttgacg ttggtggaaa gctcggtcat ttctgccccg
    10501 gcctggcggg cttcttcttc tgcccatgcc agtaatttac tgccgatatt cagaccgcgc
    10561 gcctgcggca tcaccaccag ttcctgaatt tcgccgatcc agttgacatg atgcagatga
    10621 aactgcaaat gcaggccgat catgccgaca acttcgccat ccagcagcgc cagatggtag
    10681 cgcatgttcg gatcgcgcag attggcgtta aaccccacgc gaaacgcgtg gtggtcaaac
    10741 tccgcctgtt ttagctcaca aatcagcgcg taaactgcgt cggtgtcgta ctgcgtagcc
    10801 gggcgaagct cacaagcagg catggtgttt ctccttctga tgaatcagcg tcagcagctt
    10861 gtcgaccgac tggcgcaggc tgccgtcatt attgagcgta agacaatcct gaggagtata
    10921 gcgggcagcg cgcgccagcc gggcgttaat ttcactggca ttttcacgac cacggttttc
    10981 caggcgctgg cgcaggatct ctggcgaaac ctgtaaacaa acgggcagca gcgccgattg
    11041 atagcgcgcc cgcgcctgcg gcagatgggc gcgtgagccg ttgaccacca cgtcaaatcc
    11101 agcgtgcagc cagaggtcaa tctcgacgcc gacgccataa tacagaccgt tagcgtgcca
    11161 gcttaaggcc agaaggttct gccccgcgcg ggtaaaaaac tcctgctcgc tcagggcgat
    11221 atggttttca cttccggcgc tggcggcgcg cgtgatgtag cgatgcgcta ccagtagctg
    11281 agtttgttcc cgctggcgga gttccgtcaa cagactgtct tttccggagc cagaggcccc
    11341 cattaaccaa atcagttttc ccgtcatcag aacacccttt taccctgacg ccagacgtgg
    11401 tcgatatgaa tgtggttgcc cttgcgatgc gccagcacca ggtcggcgcg tttgccctcg
    11461 ccaatcaccc cgcgatcctg aagattaagc gcctgcgccg gatttttagt caccagcttc
    11521 accgcctgcg gcagcgtaaa gcggttgctc tcgtcatcgg cgacgcgaaa tgccgcatcg
    11581 agcaggctgg cggggtagta gtcggaagag aggatatcca gcaggccaag ctgcgccagt
    11641 tcactggccg ccacgttgcc ggagtgcgaa ccgccgcgca cgatattcgg cgcgcccatc
    11701 agcacgttca tgccatgctt gcgcgaggct tctgccgctt cgaacgtggt gggaaattcg
    11761 gcgatcacgc tgccaagctg gtgggattcg gcaacgtggg cgtgcgtggc gtcatcgtgg
    11821 ctggcgaggg caatgtgtcg cgcgcggcac attgcggcga tagtttcgcg attaggctgt
    11881 gaccagcgtg cggcaagcgc cagctgttcc tcttcgtact gctgcatctg cgcatcggtg
    11941 agggaatatt tgccctgata atattcgcga tacttctcgc gattggcgaa ctggcgctgg
    12001 cctggcgagt ggtccatcag cgataccagc gtcaccggtt cgcgctgcac cagtttttca
    12061 aacagcggca acgtggtgtg gtgcggcagt tcgcagcgca gatgcagacg gtgctcggcg
    12121 cggttgacgc cgcgtttctg cgtctcttcg atggcgttga tcatcttctc cagattctcc
    12181 agccgatcgc cgccgtcgcg cacgtcgcca atcgccaccg cgtccagcac ggtggtgatg
    12241 ccgctcgcca ccatcagcgc gtcgtggcta ctcattgccg agtgggcggg ccagtccact
    12301 tttggacgcg gggtgaagaa tttatccaga ttatcggtat gcagctcaat cagccccggc
    12361 agcagccagc caccttcgcc gtccatcgct tccggctggc agctctggct ttcggcaaag
    12421 gcgcgaattt cgccatcctg tacttccagt gaaccgtgca ccacttcgtt ttccagcacc
    12481 agtttgacgt tattgataat catgaagaga ctcccattgg gtgcaggcgg tcggcgacgt
    12541 cattgcgtat ggcttcgtca tggaagatac cgacgatggc cgcgccacgg gctttggctt
    12601 cgcgaatgag ttccaccacc gcggcgctgt ttttggcgtc cagcgaggcg gtgggttcat
    12661 ccagcagcag aatcggatag tcgacgataa agccacgggc gatgttgacg cgctgctgtt
    12721 cgccgccgga gaaggtcgat ggtgccaggt gccacaggcg ttcaggcacg ttcaggcgcg
    12781 tcagtaatcg ggcggcttta gcggcgcagg cttcacgcgg tacgccggta tcgagcagcg
    12841 gctgcatcac cacttccagt gccgaaatac gcgggatgac gcgcagaaac tggctcaccc
    12901 agccgatggt ggttttgcgg atctccacca ctttgcgggc tggcgcggtg accaggtcta
    12961 cccattcctc accgtgtttg atctggattt gcccttcgtc gggcagatag ttggcgtaca
    13021 gcgagcgcag cagggttgat tttccgctgc cggagtggcc gtgaagcacc acgcattcgc
    13081 ctgcgttgac ggtgagcgag gcacgttgta agacgggcag gcgcacgccg ttttgctgat
    13141 gcaggatgaa ggttttactg acgttttgta cgttaatcat ttttcgcctc gtggttcggg
    13201 tgtcggatgt gacgctgacg cgtcttatcc gacctacggg gagcgcattt gtaggccgga
    13261 taaggcgttt acgccgcatc cggcaccggc tcaattctgc aaaaccgatg acaccagcag
    13321 ttgtgtatac ggatggtgcg ggtcgtcgag cacgcggtcg gttaacccac tctccactac
    13381 ttgcccctgc ttcatcacca gcaaacggtc cgccagcagg cgggcgacgc ctaaatcgtg
    13441 ggtgacaatc accaccgcca ggttcagctc caccaccagg ccgcgcagca ggtcgagcag
    13501 gcgcgcctgc acagatacat ccagcccgcc ggttggctcg tccataaata ccagcttcgg
    13561 atgcgtcacc aggttgcggg caatctgcaa acgctgctgc ataccgccgg aaaaggtggt
    13621 cggcaggtcg tcgatccggt tggcgggaat ttccacctct tccagccact tctgcgcggt
    13681 ggcacgaata tcgccgtaat gacgcgcccc ggtcgccatc agccgctcgc cgatattgcc
    13741 gcctgccgac acctggcggc gcaggccgtc gagtggatgc tgatgcacca cgccccattc
    13801 ggtgcgcagc aggcgacggc ggtcggcctc gctcatgcca tagagggaac ggttttcata
    13861 gcgaatttcc ccctgctgcg gcgtcaggcg cgcggagatc gacttcagca gcgtggtctt
    13921 cccggagccg gattccccga cgatgcccag cacttccccc ggccataaat caaaagagac
    13981 atcgctaaag cctttgcccg gcgcgtaaag gtgggtcagg ttattgaccg aaagtaacgg
    14041 ttgattcatt ggttttttgc ctcgctctgt tggcggcaat aatcggtatc ggagcagaca
    14101 aacatgcggt ttccggcgtc atccagcacc acttcgtcga gatagctgtg ggtcgatccg
    14161 cagatggcgc atggctcatc ccactgctga acggtgaacg ggtgatcgtc gaaatcgaga
    14221 ctttccacgc gggtaaacgg cggcaccgca tagatgcgct tctcgcgccc tgcgccgaac
    14281 agctgcaggg cgggcatcat gtccattttc gggttatcga atttcgggat cggcgacggg
    14341 tccatcacgt agcgcccgtt caccttcacc ggataggcat aggtggtggc gatatgaccg
    14401 aagcgggcga tatcttcata cagtttcacc tgcatcacgc cgtactcctc cagcgcgtgc
    14461 atggtgcggg tttccgtttc gcgcggctcg ataaagcgca gcggttcggg gatcggcacc
    14521 tggaaaataa tgatctgatc ttcggtgagc ggcgtttcgg ggatgcgatg gcgcgtctgg
    14581 ataagcgtcg catcgtccgt gcgttcggta gtgtttaccc cggtcacgcg cttaaagaag
    14641 ttacggatcg acaccgcgtt ggtggtgtcg tccgcgccct ggtcaatcac cttcagcaca
    14701 tcgctttcgc caatcacgct ggcggtaagc tggataccac cagttcccca gccgtacggc
    14761 atcggcatct cgcgcccgcc aaacggcacc tgataaccgg ggatcgccac cgcttttaag
    14821 atggcgcggc ggatcatgcg tttggtctgc tcgtcgaggt aggcaaagtt gtagccgctc
    14881 agattagcca tggttctgct cctgttgcag acgtttgagt agctccagtt cggcctggaa
    14941 atcgacgtag tgcgggagtt taaggtgcga gacaaagcct gcggcttcga cgttgtcggc
    15001 atgcgccagc acgaactctt catcctgcgc cgggcctgtc gcgtgctcgc cgtactccgg
    15061 ggcttgcaga gcgcggtcaa ccagcgccat cgccatcgct ttgcgctcgc tcatgccgaa
    15121 caccagcccg tagccgcgcg tgaagtgcgg cggctcatcc ggcgggtcga taaaaccgtt
    15181 gaccatttca cattcggtca tcagcagttc gccgacgttc accgcaaatc ccagctcttc
    15241 cggcacaatc gacacgtcga tatagccgct gcggatttcg cctgcgaacg gatgattgcg
    15301 tccgtaacca cgctgggtgg agtaggccag cgccagcaaa tagccttcgt cgccgcgcat
    15361 taattgttgc aggcgggagg agcgtgagca ggggtaaacc ggcggcgtgc gggtgatgtc
    15421 gtccggctgt gcgccgctat cttcttcaaa cttcgccagc ccctgacgcg ccagcaggct
    15481 gaaaacgtgc ggcgacggct gttgttcgct gtcggctgtg gtcagcgtcg gcgcttcgcc
    15541 gtttgccagc agggtgaaat cgagcaggcg atgggtgtag tcgtaggttg ggccaagcag
    15601 ctggccgccg ggaatatctt tataaaccgc tgaaatacgc cgttcgagac gcatctccgt
    15661 ggtgtcgagc ggctcgctta ccgcaagctt cgccagcgtg gtgcggtagg cgcgtagcag
    15721 gaaaatcgct tcgacgttat cgccgctggc ctgtttcagc gccagcgccg ccagttcgcg
    15781 gtcggcaatg ccgccttcgg tcatcacgcg atctactgca agattaagct gctgttcaat
    15841 ctgggcgacg ctcagttcag gcaaatcggt attgccccgg cgtcggctct cttgcagggc
    15901 gtgggcggcg tcgatcgcct tctcgccccc tttcacggca acgtacatca gcacacctcc
    15961 acatgagtgg ttcgcgggat agccagcagg cgctcgccgc aggtcaggat caggtcgatg
    16021 ccgagcggga acgggtgcgg gcgctcggta agttcgtgca gaatgcactc cggcagctgc
    16081 ggggcgatca ttcgttcttc ggcaataccc gcgccagtaa ggcgcagcat gcgcccgccg
    16141 ctcaggctga cgacctgtaa aatcagcgtc gcgcccgctt ctggcgcaac agcggtgccg
    16201 ctggaaaggg cgttaagctg ttcgctggaa atcgcctcat ccgttaccgc gaaggtcgcc
    16261 agttccggct gattgaccag cggcgcgttg gtatgaaaac gcaggctctg gctgacgata
    16321 tcgttactta atggcgcaga aagccacacc ggcgtgtcgt tatcggccag cgtcagcagc
    16381 acgctggtgg tggcgatatt cagcggctgc cagccgcgtt tgagctgatg cagggcgaca
    16441 atcacgcccg gctcgctcat ggcctttaac aggcgacgaa aactgtgctg ggcatcctgc
    16501 acgggaagca taaaagcggt ttccagggtc atgcgttatc tccgcgaacc atcgtaaaga
    16561 agtcgacccg gctggcgttt acttcggcct ggcgtgcggc aatgcgtgcc atacggtcag
    16621 cgttcagcgg ggcaataaga gtttctgata agttttgaaa atggcgggtt tgctgcatca
    16681 gcgcgtcgat cagcgcgcag cgttcggcgt gctgtttgtc gcgccccagc acccagctgt
    16741 agccgagcgt gccgtcagtc aggcgtacgg cggcgcgggt gagcgtggcg tcgccagcaa
    16801 aaaagcgttc gccggtgcca cccatccgcg cctgaatctg caccaggccg gtttcagcgg
    16861 cgcggattac ttcatagtcg gcggtgatgt tcagcgcgtt caggcgggct gccagctcag
    16921 tcggttggct gtgcgccagt acggacatcc agtgctggcg ggtcgcggta tctgcgtgca
    16981 ttcagtgctc catagtgaat tcaatcatgt cggcgcgcgt caggctgacg gagtactccg
    17041 ccgggctgct ttcaccgtca cggtggttaa gggtgcgcac gcacagcagc ggcgacatat
    17101 tcgggatttc aagacgctgg cactctttgg cctgggcgcg gcgggcgctg atccgcgtct
    17161 ggctgcggcg cagcgcaatt ccggtttgct cgcgcagaaa atcgtgcagt gagccgctgt
    17221 cgaagcgttg cagcgtcggc cagagggtga ggtccgcaaa gtagtggtcg attaaacaga
    17281 gcgcgacgcc gttgacccgg cgcagggtgc gcaggtggat aacgttctcg ccctcggtta
    17341 tccccagcgc gtcagcgacg tgaccggagg ccgggcgcag caccgacagc agtttttcgc
    17401 tggtgggatg gctgccctga tccagcaggt tctggctaaa acgcgcctgg gcgttgagcg
    17461 ggtaatcgaa cgggcgcatc agcaccagta cgccgacgcc ctgacggcgc tgtacccagc
    17521 ctttttccac cagttggtcg atggcgcggc gcagggtgtg gcggttcacc tcaaagcgcg
    17581 ccgccagttg ctgctcggcg ggaagatagt cgccgcagcg gtagtgttga cgaagctcct
    17641 gctcaagttt tgcggctatc tcctgatagc gtgttgggta gctggtcgga tgtgtagaca
    17701 agtgcatagc tatcaatgcc tcgcttatca gataaagtgc ttacgcaacc gttgagagag
    17761 gaaatccagc aggctgaccg tgacgataat cagcaccatc agggcgcagg tttgctggaa
    17821 ctggaaaccg cgaatcgctt cccacagggt gacgccgatc ccgcctgcac cgaccatgcc
    17881 gacgacggtc gccgagcgga cgttggattc gaaacgatag agggagtagg agatcagcag
    17941 cggcatcacc tgtggcagca cgccgtagag gatctcttcc agcttgttgg caccggtggc
    18001 gcgaatgccc tccaccgggc cgggttcgat cgcttctacc gcttcggaaa gcagcttgga
    18061 gagcacgccg gtggtgtgga taaacagcgc cagcacgcca gcgaacgggc caaggccgac
    18121 ggcgaccacg aacagcatgg cgaagaccat ttcgttaatg gcgcggcagg cgtccatcag
    18181 gcggcgtacg ggctggtaaa cccaccacgg caccaggttt tcggcgctca tcagaccgaa
    18241 ggggatggag agaaccaccg ccagcgcggt gccccagacg gcgatttgca gcgtgacggc
    18301 catttcggtg aggtaatcct gccactggct gaaatcgggc gggaagaagt cggcggcgaa
    18361 ggttgccatg ttgccgccgt ctttgatcag cgtaagcggg gccatttccg cgccctgcca
    18421 cgagacgacc aacacggcga gaacaatggc ccagctcaga agcgagaacc agctgcgctt
    18481 gggtggggcg atggtgatgg tttgcatgtt tggctccgtg attgtgtgct cgatcggttc
    18541 cctcgcccct tcggggagag ggagaaaacc attactgcac cgctttactt accgaactca
    18601 tcgcgcttaa cgcgttgttc aggcggtcca ggtcatccag ctgcgcctga atcgcggtgg
    18661 ttttcgccag cttgtcctgc tcattcagcc ctttattgcc tttcacgccc tgcatctctt
    18721 taaacagcgc gagctggcga atcggtacca gttgcaggtc gctggaggcg cggaacgggg
    18781 cccagcccag gcgttccagc accgctttct cttccggcgt cttgccgtaa ttcataaaga
    18841 agtcgtagat cttgtctttg gtagtttcgg acagattttt gcgccagacg atcggatcgc
    18901 ctgggatcag cggcgatttc ctgatcacct tcagttcttt gagcttctct ggtgcggagg
    18961 ttttcagctt gtcgaggttt tcggtgttgt tggtcgccac atccacttgc ttgttggcga
    19021 cggccagcgc gttggtttca tgcccggcgt tgacggtgcg cttgaagtcg ctggcggaga
    19081 tattgttttt ggcaaagacg tagtaaccgg ggacgaggaa gccagaggtg gagttaggat
    19141 cgccattgcc aaaggtaaga tctttacgct tcgccagcag atcgttcagg ttgttgatcg
    19201 ggctgtcttt gttgacgatc aacacgctcc agtaacctgg cgatccatcc gccgcgactg
    19261 tctgggcgaa gacctgaccg ttggcgcgat ccaccgcttc catcgccgac aggttgccgt
    19321 accaggcgat atccacttta ttgaagcgca tcccctggat aatgcccgcg tagtccgggg
    19381 caaagaaggc gttgaccttt acgcccagct tcttctccat atcctgtaag aacggcgtcc
    19441 attgcggttt caggttttgc tgtgattccg ttgaaataat gccgaaattc aacgcctttt
    19501 cctgctcttc ggcgtgcgcc gggcttaaca gggtgctgag gctgaacatg ctggtgaagg
    19561 ccagcgaggc aattatctta gcgttcattc gttttcctca atgatgggga tgtcaggcag
    19621 ctttcgcgtt ctcttcgacg cggttaatgc tgcggtagag atggtcaaaa cgttcgttat
    19681 caaactgttg gctgctgccg tcgtagaaga cgtgcccctg gcgcagggcg acgatgcgtt
    19741 cgcagtagcg cagggcgtaa tccacctgat gcagcgtgac gaccacggta atgccgtcgt
    19801 tctggttaat gtcgcgcagg gtgtccatca cgatgcgcgc cgattccggg tccagcgagg
    19861 cgatgggttc gtccgccaga atcaccttcg cctgctgcat cagcgcgcgg gcaatcgcta
    19921 cacgctgctg ctggccgccg gagagggtgg aaacgcgctg atgggcaaaa tgcaccatgc
    19981 caacgcgggt cagcgcctgt aacgcgcgct gtttctgctc gcgggtgaag tagctaaaac
    20041 aggtgcgcca gaatggcgtg ctgccgagcg cgccaatcag cacgttctcc agtacgctca
    20101 ggcgattcac caggttgaat tgttggaaga tgtagccggt gttggcgcgg cttttgcgga
    20161 tatcgcgggc caggcggcct tcgcgctgga ctgtgcggcc cagcagctcg atatggctac
    20221 cggcagattt atcgccggta atcaaaccgc ttaagtgacg taaaagggtg gatttgccgg
    20281 aacccgacgg cccaagcaga gccaccattt caccgtgatg aatgttcaga tcaaccgcgt
    20341 gcagcgcctg atgctgattg aaggttttgg cgagcttctc gacacggata atcgtttgca
    20401 tgatgcagcc tccctaaaaa agtggctcca tcgtggcgga ttattgtgac gatttggtta
    20461 attaaaagtg actaacagat gaagagttaa cgggaattcg atgacagtgc gggagggcgg
    20521 gcctcccggc ggattattgc gttggttgtt gtttgacgac attaatcatc cacggtacgc
    20581 caaatttatc ggtgactttg ccgaagccat gcgcccagaa agtttcctgc caggccattt
    20641 cgatttttcc gttggcggca agattgtcaa accagcgttt cccttcttcg acctgttgcg
    20701 aatcgagcac tagcgtaaag ccggagtagc tggcttttcc tgacggtata gcatcgctca
    20761 tcatgatatc gcttccggca atgcgcacat tggcgtgggc gatggcggta tcgggaaatt
    20821 gcattccgga agggcagttc tcggcgctgt cctgcgctga ttttggcatt tcgccgaagc
    20881 tgattttata gagcagttca gcgcccaacg tacgttgata ataagcaatt gcgtcggcac
    20941 agttaccggc aaaagagagg tagggactta acggcatgat ggtgacctca gttaagagaa
    21001 gccagttaag tgtagttcga aatttataca gatgagaggg aagcctgata agacgcggtc
    21061 agcgtcgcat caggcagtcg gcatcgttgc cggatgcggc gcgagcgcct tatccggctt
    21121 accgatcaca atacaatcag ttctttttca caaactcaga tttcagtttc atcggaccaa
    21181 aaccgtcgat tttgcaatcg atgttatggt cgccttcaac caggcggatg tttttcactt
    21241 tggtgccaat tttcagcatc gaagagctac ctttcacctt cagatcttta atgatggtaa
    21301 cgctgtcgcc gtcagccagc agattgccgt tagcatcttt aacgatcagc tcgtcgcttt
    21361 cctgtgcagg ttctgcgtcg ttccattcgt aggcacattc cgggcagatg tacatgccgt
    21421 tatcttcgta ggtgtattcg gagttgcatt ttgggcagtg tggtaatgac atgtggattt
    21481 cctcaaaagt cagcagggca aaagcgccaa aaaacggcag attgccgaaa aaggccgcaa
    21541 ttatacacaa aatccctgag tttgtcgggg gtactgctga ttttagacga cgatcgtttt
    21601 catttgaaag gaaacgcaaa aagaaaataa tctttttgc
//
LOCUS       DADXDL010000082        21577 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.082, whole genome shotgun sequence.
ACCESSION   DADXDL010000082 DADXDL010000000
VERSION     DADXDL010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21577
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.082"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            124..1554
                     /locus_tag="IRB70_003594"
     CDS             124..1554
                     /locus_tag="IRB70_003594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418298.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 family protein"
                     /protein_id="HBC0633459.1"
                     /translation="MIRKSATGVIVALAVIWGGGTWYTGTQIQPGVEKFIKDFNDAKK
                     KGEHAYDMTLSYKNFDKGFFNSHFQMQITFDNGAPDLNIKPGQKVAFDVDVEHGPLPI
                     TMLMRGNVIPALAAAKVNLVNNELTQPLFIAAKNKSPVEATLRFAFGGSFSTTLDVAP
                     AKYGKFSFGEGQFTFNGDGSSLSNLDSEGKVEDIVLQFSPMNKVTAKSFTFDSLTRLE
                     EKKFPVGESESKFNQVNIINQGEVVAQIDAFVAKTRLDRVKDKDYINVNLTYELDKLI
                     KGNQQLGSGEWSLIAESIDPSAVRQFIIQYNIAMQKQLAAHPELANDEVALQEVNAAL
                     FKEYLPLLQKSEPTIKQPVRWKNALGELNANLDISIADPAKSSSSTNKDIKSLNFDVK
                     LPLNVVTETAKQLNLSEGMDAEKAQKQADKQISGMMTLGQMFQLITIDNNTASLQLRY
                     TPGKVVFNGQEMSEEEFMSRAGRFVH"
     gene            complement(1595..2527)
                     /locus_tag="IRB70_003595"
     CDS             complement(1595..2527)
                     /locus_tag="IRB70_003595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBC0633460.1"
                     /translation="MANLLNKFIMTRILAAITLLLSIVLTILVTIFCSVPIIIAGIVK
                     LLLPVPVIWRKVSRFCDFMMYCWCEGLAVLLHLNPHLQWEVHGLEGLSKKNWYLLICN
                     HRSWADIVVLCVLFRKHIPMNKYFLKQQLAWVPFLGLACWALDMPFMKRYSRAYLLRH
                     PERRGKDVETTRRSCEKFRLHPTTIVNFVEGSRFTQEKHQQTHSTFQNLLPPKAAGIA
                     MALNVLGKQFDKLLNVTLCYPDNNRQPFFDMLSGKLTRIVVHVDLQPIADELHGDYIN
                     DKSFKRHFQQWLNSLWQEKDRLLTSLMSSQRQEK"
     gene            2891..5677
                     /gene="polA"
                     /locus_tag="IRB70_003596"
     CDS             2891..5677
                     /gene="polA"
                     /locus_tag="IRB70_003596"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBC0633461.1"
                     /translation="MVQIPQNPLILVDGSSYLYRAYHAFPPLTNSAGEPTGAMYGVLN
                     MLRSLIMQYKPTHAAVVFDAKGKTFRDELFEHYKSHRPPMPDDLRAQIEPLHAMVKAM
                     GLPLLAVSGVEADDVIGTLAREAEKAGRPVLISTGDKDMAQLVTPNITLINTMTNTIL
                     GPEEVVNKYGVPPELIIDFLALMGDSSDNIPGVPGVGEKTAQALLQGLGGLDTLYAEP
                     EKIAGLSFRGAKTMAAKLEQNKEVAYLSYQLATIKTDVELELTCEQLEVQPPAAEELL
                     GLFKKYEFKRWTADVEAGKWLQAKGAKPAAKPQETSVADEAPEVTATVISYDNYVTIL
                     DEETLKEWIAKLEKAPVFAFDTETDSLDNISANLVGLSFAIEPGVAAYIPVAHDYLDA
                     PDQISRERALELLKPLLEDEKALKVGQNLKYDRGILANYGIELRGIAFDTMLESYILN
                     SVAGRHDMDSLAERWLKHKTITFEEIAGKGKNQLTFNQIALEEAGRYAAEDADVTLQL
                     HLKMWPDLQKHKGPLNVFENIEMPLVPVLSRIERNGVKIDPKVLHNHSEELTLRLAEL
                     EKKAHEIAGEEFNLSSTKQLQTILFEKQGIKPLKKTPGGAPSTSEEVLEELALDYPLP
                     KVILEYRGLAKLKSTYTDKLPLMINPKTGRVHTSYHQAVTATGRLSSTDPNLQNIPVR
                     NEEGRRIRQAFIAPEDYVIVSADYSQIELRIMAHLSRDKGLLTAFAEGKDIHRATAAE
                     VFGLPLETVTSEQRRSAKAINFGLIYGMSAFGLARQLNIPRKEAQKYMDLYFERYPGV
                     LEYMERTRAQAKEQGYVETLDGRRLYLPDIKSSNGARRAAAERAAINAPMQGTAADII
                     KRAMIAVDAWLQAEQPRVRMIMQVHDELVFEVHKDDVDAVAKQIHQLMENCTRLDVPL
                     LVEVGSGENWDQAH"
     gene            complement(6059..6691)
                     /locus_tag="IRB70_003597"
     CDS             complement(6059..6691)
                     /locus_tag="IRB70_003597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418301.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBC0633462.1"
                     /translation="MTNLNYQQTHFVMSAPDIRHLPSDTGIEVAFAGRSNAGKSSALN
                     TLTNQKSLARTSKTPGRTQLINLFEVADGKRLVDLPGYGYAEVPEEMKRKWQRALGEY
                     LEKRQSLQGLVVLMDIRHPLKDLDQQMIEWAVDSNIAVLVLLTKADKLASGARKAQLN
                     MVREAVLAFNGDVQVETFSSLKKQGVDKLRQKLDTWFSEMQPVEETQDGE"
     gene            7273..7782
                     /gene="yihI"
                     /locus_tag="IRB70_003598"
     CDS             7273..7782
                     /gene="yihI"
                     /locus_tag="IRB70_003598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Der GTPase-activating protein YihI"
                     /protein_id="HBC0633463.1"
                     /translation="MKPSSSNSRSKGHAKARRKTREELDQEARDRKRQKKRRGHAPGS
                     RAAGGNTSSGSKGQNAPKDPRIGSKTPIPLGVTEKVTKQHKPKSEKPMLSPQAELELL
                     ETDERLDALLERLEAGETLSAEEQSWVDAKLDRIDELMQKLGLSYDDDEEEEEDEKQE
                     DMMRLLRGN"
     gene            7971..9344
                     /gene="hemN"
                     /locus_tag="IRB70_003599"
     CDS             7971..9344
                     /gene="hemN"
                     /locus_tag="IRB70_003599"
                     /EC_number="1.3.98.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBC0633464.1"
                     /translation="MSVQQIDWDLALIQKYNYSGPRYTSYPTALEFSEDFGEQAFLQA
                     VARYPERPLSLYVHIPFCHKLCYFCGCNKIVTRQQHKADQYLDALEQEIVHRAPLFAG
                     RKVSQLHWGGGTPTYLNKAQISRLMKLLRENFQFNADAEISIEVDPREIELDVLDHLR
                     AEGFNRLSMGVQDFNKEVQRLVNREQDEEFIFALLNHAREIGFTSTNIDLIYGLPKQT
                     PESFAFTLKRVAELNPDRLSVFNYAHLPTIFAAQRKIKDADLPSPQQKLDILQETIAF
                     LTQSGYQFIGMDHFARPDDELAVAQREGVLHRNFQGYTTQGDTDLLGMGVSAISMIGD
                     CYAQNQKELKHYYQQVDEQGNALWRGIALTRDDCIRRDVIKSLICNFRLDYAPIEQQW
                     DLHFADYFAEDLKLLAPLAKDGLVDVDEKGIQVTAKGRLLIRNICMCFDTYLRQKARM
                     QQFSRVI"
     gene            complement(9573..9683)
                     /locus_tag="IRB70_003600"
     CDS             complement(9573..9683)
                     /locus_tag="IRB70_003600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YshB family small membrane protein"
                     /protein_id="HBC0633465.1"
                     /translation="MLESIINLVSSGAVDSHTPQTAVAAVLCAAMIGLFS"
     gene            complement(9795..11204)
                     /gene="glnG"
                     /locus_tag="IRB70_003601"
     CDS             complement(9795..11204)
                     /gene="glnG"
                     /locus_tag="IRB70_003601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012133942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(I)"
                     /protein_id="HBC0633466.1"
                     /translation="MQRGIVWVVDDDSSIRWVLERALAGAGLTCTTFENGAEVLEALA
                     SKTPDVLLSDIRMPGMDGLALLKQIKQRHPMLPVIIMTAHSDLDAAVSAYQQGAFDYL
                     PKPFDIDEAVALVERAISHYQEQQQPRNVQLNGPTTDIIGEAPAMQDVFRIIGRLSRS
                     SISVLINGESGTGKELVAHALHRHSPRAKAPFIALNMAAIPKDLIESELFGHEKGAFT
                     GANTIRQGRFEQADGGTLFLDEIGDMPLDVQTRLLRVLADGQFYRVGGYAPVKVDVRI
                     IAATHQNLEQRVQEGKFREDLFHRLNVIRVHLPPLRERREDIPRLAHHFLQVAARELG
                     VEAKLLHPETEAALTRLAWPGNVRQLENTCRWLTVMAAGQEVLIQDLPGELFESTVPE
                     STSQMQPDSWATLLAQWADRALRSGHQNLLSEAQPELERTLLTTALRHTQGHKQEAAR
                     LLGWGRNTLTRKLKELGME"
     gene            complement(11216..12265)
                     /gene="glnL"
                     /locus_tag="IRB70_003602"
     CDS             complement(11216..12265)
                     /gene="glnL"
                     /locus_tag="IRB70_003602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen regulation protein NR(II)"
                     /protein_id="HBC0633467.1"
                     /translation="MATGTQPDAGQILNSLINSILLIDDNLAIHYANPAAQQLLAQSS
                     RKLFGTPLPELLSYFSLNIELMQESLEAGQGFTDNEVTLVIDGRSHILSVTAQRMPDG
                     MILLEMAPMDNQRRLSQEQLQHAQQVAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
                     DPSLLEYTKVIIEQADRLRNLVDRLLGPQLPGTRVTESIHKVAERVVTLVSMELPDNV
                     RLIRDYDPSLPELAHDPDQIEQVLLNIVRNALQALGPEGGEIILRTRTAFQLTLHGER
                     YRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARNLIDQHSGKIEFTS
                     WPGHTEFSVYLPIRK"
     gene            complement(12439..13848)
                     /gene="glnA"
                     /locus_tag="IRB70_003603"
     CDS             complement(12439..13848)
                     /gene="glnA"
                     /locus_tag="IRB70_003603"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020233234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--ammonia ligase"
                     /protein_id="HBC0633468.1"
                     /translation="MSAEHVLTMLNEHEVKFVDLRFTDTKGKEQHVTIPAHQVNAEFF
                     EEGKMFDGSSIGGWKGINESDMVLMPDASTAVIDPFFADSTLIIRCDILEPGTLQGYD
                     RDPRSIAKRAEDYLRSTGIADTVLFGPEPEFFLFDDIRFGSSISGSHVAIDDIEGAWN
                     SSTQYEGGNKGHRPAVKGGYFPVPPVDSAQDIRSEMCLVMEQMGLVVEAHHHEVATAG
                     QNEVATRFNTMTKKADEIQIYKYVVHNVAHRFGKTATFMPKPMFGDNGSGMHCHMSLS
                     KNGVNLFAGDKYAGLSEQALYYIGGVIKHAKAINALANPTTNSYKRLVPGYEAPVMLA
                     YSARNRSASIRIPVVSSPKARRIEVRFPDPAANPYLCFAALLMAGLDGIKNKIHPGEA
                     MDKNLYDLPPEEAKEIPQVAGSLEEALNELDLDREFLKAGGVFTDEAIDAYIALRREE
                     DDRVRMTPHPVEFELYYSV"
     gene            14221..16044
                     /gene="typA"
                     /locus_tag="IRB70_003604"
     CDS             14221..16044
                     /gene="typA"
                     /locus_tag="IRB70_003604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-dependent GTPase TypA"
                     /protein_id="HBC0633469.1"
                     /translation="MIEKLRNIAIIAHVDHGKTTLVDKLLQQSGTFDSRAETQERVMD
                     SNDLEKERGITILAKNTAIKWNDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF
                     DGPMPQTRFVTKKAFAYGLKPIVVINKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF
                     PIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYV
                     GVIGIGRIKRGKVKPNQQVTIIDSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIVAI
                     TGLGELNISDTVCDTQNVEALPALSVDEPTVSMFFCVNTSPFCGKEGKFVTSRQILDR
                     LNKELVHNVALRVEETEDADAFRVSGRGELHLSVLIENMRREGFELAVSRPKVIFREI
                     DGRKQEPYENVTLDVEEQHQGSVMQALGERKGDLKNMNPDGKGRVRLDYVIPSRGLIG
                     FRSEFMTMTSGTGLLYSTFSHYDDVRPGEVGQRQNGVLISNGQGKAVAFALFGLQDRG
                     KLFLGHGAEVYEGQIIGIHSRSNDLTVNCLTGKKLTNMRASGTDEAVVLVPPIRMTLE
                     QALEFIDDDELVEVTPTSIRIRKRHLTENDRRRANRAPKDD"
     gene            complement(16135..16830)
                     /locus_tag="IRB70_003605"
     CDS             complement(16135..16830)
                     /locus_tag="IRB70_003605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000563094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBC0633470.1"
                     /translation="MICRLIALDLDGTLLNSKKMISPASVSALQSAQQAGVKIILATG
                     RSHSEALPYYQQLQLTEPMICCNGSYLYHPRQRQILRPLPLDTQKVEQLRRWFSQQAL
                     QPHIYTYDDFVLQISLVHRKASLLRQAEEFARQELSLACSWSWHHQLDITQAGCEKGK
                     SLAWYARQQNIVLDEIIAFGDNDNDAGMLRMVGKGIAMGNGSSLAKVSADRVIGHNNT
                     DAIADFLDAQGFR"
     gene            complement(16827..17684)
                     /locus_tag="IRB70_003606"
     CDS             complement(16827..17684)
                     /locus_tag="IRB70_003606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015953881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBC0633471.1"
                     /translation="MTLKQIQTLIYRGEIKSCNYRCGYCPFHKQDRNDKQQDEAALWR
                     MVEHLPALGSPLNVLITPYGEALRYRYYMAAMAKISRYSHVQAVGIQTNASFNLSSLI
                     ATMQDNQGDLAKLRLWCSFHPSQVSKDVFLKQILAIKDAGITCSVGAVASVDNYDTFQ
                     WLRAHLPADIYFWLNANERDKRPTSDERNSQFQMLDPLYHLETSLWPANVEFCIGGKK
                     SVFMNADGDLFACNISKIKIGNLYQQQLSSPACMARQCHCYLAYHLRQDIPALSQFDA
                     ERCFRIFSL"
     gene            complement(17681..18919)
                     /locus_tag="IRB70_003607"
     CDS             complement(17681..18919)
                     /locus_tag="IRB70_003607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4012 family radical SAM protein"
                     /protein_id="HBC0633472.1"
                     /translation="MNNESIYQQYMYSYPHKTAYRELNNIAFADVKSRIYEHKTHLYI
                     HMPFCQSRCGFCNLFTCTGANNAFIDNYIEAIIVQARQMQLAPVDWDSFTIGGGTPLL
                     LNVGQLLRLFNGVFDELQVDAHIFKAIETSPSDTTAEKVALLRQLAVNRVSIGVQSFN
                     DLELATLHRRHSATNAHRALELLRRGNFPILNIDIIYGIPGQTAASLMASLNQALDYQ
                     PDELFLYPLYNMPRQPDMYSLYIEARDRLLHEGYTQTSMRRFVRVNNDSAVESCGFEN
                     SLALGAGGRSYLGNLHYCTPWSQNQPASRQIVADFIARQDKTLINHGYVLSQAEMKRR
                     FVIKNLFFYKGLSLRDYQRQFSSEVLSDFPLLGDFIKQDYCHQQDNRILLTAQGLALS
                     DQLGPLFISPEVRRLETHKR"
     gene            complement(18912..19784)
                     /locus_tag="IRB70_003608"
     CDS             complement(18912..19784)
                     /locus_tag="IRB70_003608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000282973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4013/SEN3800 family hydrolase"
                     /protein_id="HBC0633473.1"
                     /translation="MYNVTDEVPENTRTAIHSCDGEINLNDLIAREANVLFVVLDSLR
                     FDIAFQEQEAGNTPNINRYGRWIKCEAAGNFTWPSHHSMFSGFMPKPLEAAPGHSMLF
                     FPKDIGLGRLGPKNAFAFSEETWIKGLENKGYRTICVGGVSFFNNRSGMGKVFPAMFK
                     ESYWYPNFSCTVKESMDNQLTLINKKVNAEQPLMMYINIDTIHYPNHFYIENAKPGDT
                     VETHAAALHYIDARIEKLFDTFRQTGRETLVILCSDHGTCYGEDGKYFHSFNHPIVNT
                     VPYFHFVLDGTAHE"
     gene            complement(19777..20763)
                     /locus_tag="IRB70_003609"
     CDS             complement(19777..20763)
                     /locus_tag="IRB70_003609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="STM4014 family protein"
                     /protein_id="HBC0633474.1"
                     /translation="MITLIGHPESKRTFYFCQAASRLQEHINVVNYDQALTLPLNKGM
                     VKIDPPLHQETDIRLINTVSQNYISFLHKMATRREIRFINSPEGIIHLLDKRYCKQRL
                     IEHAIPTPPILADDARSYDQLIACMRSEKVYRVFIKPNLGSGAAGVLALNLHPGDNRQ
                     VLYCAIQVAGDRLVNSKHIIRYENSDDIKLIVNAILQQENIIECWLAKARVGNKSYDL
                     RIVYVNGEIVWRVVRTSSQPITNLHLQNEAIRFADLNLPAEKVAEIDTLCLNAMKLYP
                     DVHIAGLDVLLTQKLTPYIIEINGQGDLIYQDTCEQNKIYQRQIQVMREHHV"
     gene            complement(20824..>21577)
                     /locus_tag="IRB70_003610"
     CDS             complement(20824..>21577)
                     /locus_tag="IRB70_003610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001591261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="STM4015 family protein"
                     /protein_id="HBC0633475.1"
                     /translation="RSLVISRWGECYEESCQPIIDMFAEHAERFAHLESLFIGDMESE
                     ECEISWIKQGDYSRLYAALPNLKKLTIKGTQDLELGEIAHDKLEHLEIISGGTPCNVF
                     ASLQNSQLPALKTLIVYIGVEDYGFDASLDIVMKLASKSLFPSLTHLGLVNSEEQNEI
                     VRRVLESDILPQLEVLALSCGTLTDEGAEHLLKHADRLSHLKLLDLYHHYLTEQMQKK
                     LQKTLTCTVELSEALTPEVYDDEVYMHPMFTE"
BASE COUNT         5659 a         5261 c         5363 g         5294 t
ORIGIN      
        1 ttcacgggct ttttttatta tttaataaat ataaatacat tctgataatg catcccgccg
       61 ctggacatta tttcagcata agtggatatt caaagctttg ctgttttatc agggaatatt
      121 tatatgatac gtaagtcagc tacaggtgtt attgttgcgt tagccgtaat ctggggtggt
      181 ggcacatggt acacaggtac gcaaattcag cctggtgtcg aaaagtttat taaagatttt
      241 aacgatgcta aaaagaaagg tgaacatgcc tacgatatga cgttaagtta taaaaacttt
      301 gacaaaggct tttttaattc tcattttcaa atgcaaataa catttgataa cggtgcaccc
      361 gatctcaata tcaagccagg ccagaaagtt gcatttgatg tggatgttga gcacggtccg
      421 ttgcccatca caatgttaat gcgtggtaat gtcatccccg cactggcagc ggcaaaagtg
      481 aacttagtga ataatgaact gacacaaccg ctatttatcg ccgcaaaaaa taaatcgccc
      541 gtggaagcga cattgcgatt cgcgtttggt ggctcattct ccacgacatt agatgttgcc
      601 cctgcaaaat atggaaagtt ttcttttggt gagggccagt ttacttttaa tggtgatggt
      661 agttcattgt ctaacctgga tagtgaaggc aaagtcgaag atattgttct gcaattttca
      721 ccaatgaaca aagtaacggc gaaaagtttt acctttgatt ctctgacacg attagaagaa
      781 aagaaatttc cggttggtga aagcgagtcg aaatttaatc aggttaatat tatcaaccag
      841 ggggaagtcg ttgcccaaat cgatgctttc gttgcaaaaa ccaggctgga tcgcgttaaa
      901 gacaaagatt atatcaatgt caatctgacc tacgaacttg ataagttaat aaaagggaat
      961 cagcaactcg gtagtggtga gtggtcattg attgctgaat ctattgatcc atcagcggtg
     1021 cgccaattta tcatccagta taacattgcg atgcagaagc agcttgctgc acaccctgag
     1081 ttagcaaacg atgaagttgc tctgcaagaa gtgaatgctg cattgttcaa agagtattta
     1141 ccgttattac aaaaaagtga gccgaccatt aaacaaccgg taagatggaa gaacgcactc
     1201 ggcgaactaa atgccaatct ggatatcagt attgccgacc cagccaaatc ttcatcatcc
     1261 acaaacaaag atatcaaatc gctcaatttt gatgtgaagt taccgcttaa tgtcgtcaca
     1321 gaaaccgcaa aacagcttaa tttatctgaa ggaatggatg cggaaaaagc gcaaaagcag
     1381 gctgataaac aaatcagcgg gatgatgaca ttaggtcaga tgtttcagtt aatcacgatt
     1441 gacaacaata ccgcctcgct gcagctgcgt tatacaccgg gtaaagttgt ttttaacgga
     1501 caggagatga gcgaagaaga atttatgtct cgtgccggac gttttgttca ttaaaatact
     1561 cactcgcctc tgctcattca gaggcgagta aaacttactt ttcctgccgc tgtgatgaca
     1621 tgagagacgt cagaagccgg tctttttcct gccacaatga gttcagccat tgctgaaaat
     1681 ggcgcttaaa gcttttgtca ttgatgtagt cgccatgtaa ctcatcggca ataggctgta
     1741 aatccacatg tacgacaatt cgcgtcagtt taccgcttaa catatcgaag aacggctgac
     1801 ggttattgtc cggataacac agcgtaacat taagcagttt atcgaattgt ttacccagta
     1861 catttagcgc catcgcaatg cctgccgcct ttggtggcaa caagttttga aaagtggagt
     1921 gggtttgctg atgtttttct tgcgtgaaac gggagccttc aacgaaattg acaatggtgg
     1981 tgggatgcag gcgaaacttt tcacaagaac gccgagtggt ttcaacatct ttaccacgtc
     2041 gctccggatg acgtaataaa taagcgcggg aataacgctt cataaacggc atatccagcg
     2101 cccagcacgc caggccaaga aatggcaccc aggccagctg ttgcttgagg aaatatttat
     2161 tcatcggaat gtgcttacga aacagcacgc acagtacgac aatatctgcc caactacggt
     2221 ggttacaaat aagcagatac cagttcttct tacttaaccc ttccagcccg tgaacttccc
     2281 attgcaggtg tgggttcaga tgcagtaata ccgccagacc ttcacaccag caatacatca
     2341 taaaatcaca aaaacgcgaa acctttcgcc aaatgactgg cacaggtagc aatagtttta
     2401 caatcccggc aatgatgatc gggacggagc aaaaaatagt gaccaaaatg gtcaatacga
     2461 tactcagcaa aagggttatc gcagcgagta ttctcgtcat aatgaattta ttcaaaaggt
     2521 tagccataga cagtgcgcta aaggagcgca aggcgcagat tttagcagaa aacgccccaa
     2581 ataacggatg atccttaagg agaaaaataa ttcatatcta tccacattag aaaaaatccc
     2641 attatctcaa ttattaggga tggctttatt tttaactaca tgaaaaacaa agacaaacat
     2701 catgctgtaa aaagcatgat aataaattaa aagtgatgta aataatttat gcacaaagtt
     2761 atccacatga cgatttgcga gcgatccaga agatctacaa aagattttca cgaaaagcgg
     2821 tgaaaaactc atgttttcat cctgtctgtg gcatccttta cccataatct gataaacagg
     2881 cacggacatt atggttcaga tcccccaaaa tccacttatc cttgtagatg gttcatctta
     2941 tctttatcgc gcatatcacg cgtttccccc gctgactaac agcgcaggcg agccgactgg
     3001 tgcgatgtat ggtgtcctca acatgctgcg cagtctgatc atgcaatata aaccgacgca
     3061 tgcagcggtg gtctttgacg ccaagggaaa aacctttcgt gatgaactgt ttgaacatta
     3121 caaatcacat cgcccgccaa tgccggacga tctgcgagca caaatcgaac ctctgcacgc
     3181 gatggttaaa gcgatgggac tgccgctgct ggcggtttct ggcgtagaag cggacgacgt
     3241 tattggtact ctggcgcgcg aagccgaaaa agccgggcgt ccggtgctga tcagcactgg
     3301 cgataaagat atggcgcagc tggtgacacc aaatatcacg cttatcaaca ccatgacgaa
     3361 taccatcctc ggaccggaag aggtggtgaa taagtacggc gtgccgccag aactgatcat
     3421 cgatttcctg gcgctgatgg gtgactcctc tgataacatt cctggcgtac cgggcgtcgg
     3481 tgaaaaaacc gcgcaggcat tgctgcaagg tcttggcgga ctggatacgc tgtatgccga
     3541 gccagaaaaa attgctgggt tgagcttccg tggcgcgaaa acaatggcag cgaagctcga
     3601 gcaaaacaaa gaagttgctt atctctcata ccagctggcg acgattaaaa ccgacgttga
     3661 actggagctg acctgtgaac aactggaagt gcagccaccg gcggcggaag agttgttagg
     3721 gctgttcaaa aagtatgagt tcaaacgctg gactgctgat gtcgaagcgg gcaaatggct
     3781 acaggccaaa ggggcgaaac ccgcagccaa gccgcaggaa accagtgttg cagacgaagc
     3841 gccagaagtg acggcaacgg tgatttctta tgacaactac gtcaccatcc ttgatgaaga
     3901 aacactgaaa gagtggattg cgaagctgga aaaagcgccg gtatttgcat ttgataccga
     3961 aaccgacagc cttgataaca tctctgctaa cctggtcggg ctttcttttg ctatcgagcc
     4021 aggcgtagcg gcatatattc cggttgctca tgattatctt gatgcgcccg atcaaatctc
     4081 tcgcgagcgt gcactcgagt tgctaaaacc gctgctggaa gatgaaaagg cgctgaaggt
     4141 cgggcaaaac ctgaaatacg atcgcggtat tctggcgaac tacggcattg aactacgtgg
     4201 gattgcgttt gataccatgc tggagtccta cattctcaat agcgttgccg ggcgtcacga
     4261 tatggacagc ctcgcggaac gttggttgaa gcacaaaacc atcacttttg aagagattgc
     4321 gggtaaaggc aaaaatcaac tgacctttaa ccagattgcc ctcgaagaag ccggacgtta
     4381 cgccgccgaa gatgcagatg tcaccttgca gttgcatctg aaaatgtggc cggatctgca
     4441 aaaacacaaa gggccgttga acgtcttcga gaatatcgaa atgccgctgg tgccggtgct
     4501 ttcacgcatt gaacgtaacg gtgtgaagat cgatccgaaa gtactgcaca atcactctga
     4561 agagctcacc ttgcgtctgg ctgagctgga aaagaaagcg catgaaattg caggtgaaga
     4621 atttaacctt tcttccacca agcagttaca aaccattctg tttgaaaaac agggcattaa
     4681 accgctgaag aaaacgccgg gtggcgcgcc gtcaacgtcg gaagaggtac tggaagaact
     4741 ggcgctggac tatccgttgc caaaagtgat tctggagtat cgtggtctgg cgaagctgaa
     4801 atcgacctac accgacaagc tgccgctgat gatcaacccg aaaaccgggc gtgtacatac
     4861 ctcttatcac caggcagtaa ccgcaacggg acgtttatcg tcaaccgatc ctaacctgca
     4921 aaacattccg gtgcgtaatg aagaaggtcg tcgtatccgc caggcgttta ttgcgccaga
     4981 ggattatgtg attgtctcgg cggactactc gcagattgaa ctgcgcatta tggcgcatct
     5041 ctcgcgtgac aaaggcttgc tgaccgcatt cgcggaagga aaagatatcc accgggctac
     5101 ggcggcagaa gtgtttggtt tgccactgga aaccgtaacc agcgagcaac gccgtagcgc
     5161 gaaagcgatc aactttggtc tgatttatgg catgagtgct ttcggcctgg cgcggcaatt
     5221 gaacattcca cgtaaagaag cgcagaagta catggacctt tacttcgaac gctaccctgg
     5281 cgtgctggag tatatggaac gcacccgtgc tcaggcgaaa gagcagggct acgttgaaac
     5341 gctggacgga cgccgtctgt atctgccgga tatcaaatcc agcaatggtg ctcgtcgtgc
     5401 agcggctgaa cgtgcagcca ttaacgcgcc aatgcaggga accgccgccg acattatcaa
     5461 acgggcgatg attgccgttg atgcgtggct acaggctgag caaccgcgtg tacgtatgat
     5521 catgcaggta cacgatgaac tggtatttga agttcataaa gatgatgtcg atgccgtcgc
     5581 gaagcagatt catcaactga tggaaaactg tacccgtctg gatgtgccgt tgctggtgga
     5641 agtggggagt ggcgaaaact gggatcaggc gcactaagat tcgcctgaac atgccctttt
     5701 ttcgtaagta agcaacataa gctgtcacgt tttgtgatgg ctattagaaa ttcctatgca
     5761 acaactgaaa aaaaattaca aaaaatgctt tctgaactga acaaaaaaga gtaaagttag
     5821 tcgcgtaggg tacagaggta agatgttcta tctttcagac cttttacttc acgtaatcgg
     5881 atttggctga atattttagc cgccccagtc agtaatgact ggggcgtttt ttattgggcg
     5941 aaagaaaaga tccgtaatgc ctgatgcgcc atgtttatca ggccaacggt agaagtgtaa
     6001 tctattgaat ttactggccg gatacgccac atccggcaca agcattaagg caagaaaatt
     6061 attcgccgtc ctgcgtttct tctacaggct gcatctcgct aaaccaggta tccagtttct
     6121 gccgcagctt gtccacgcct tgtttcttca gtgaagagaa ggtttcaacc tgcacatcac
     6181 cgttaaacgc cagcaccgct tcacgcacca tattcaattg cgctttacgt gcgccgcttg
     6241 ccagtttgtc cgctttggtc agcagcacca gcacggcgat attgctgtct accgcccact
     6301 caatcatctg ctgatccaaa tctttcagcg gatggcgaat atccattagc accaccagac
     6361 cttgcaggct ctgacgtttt tcgaggtact cgccgagcgc gcgctgccat ttgcgcttca
     6421 tctcttccgg gacttccgca taaccgtacc caggcaagtc aaccagacgc ttgccgtcag
     6481 ccacttcaaa caggttgata agctgggtgc gccctggggt ttttgaggtc cgcgccaggc
     6541 ttttctggtt agtcagcgtg ttcagcgcgc tggatttacc tgcgttggaa cggcctgcaa
     6601 aagccacttc aattccggta tcggaaggta ggtggcgaat atcaggcgca ctcatcacaa
     6661 aatgcgtctg ttgataattc aaattagtca aagcggtcgt ctccgtcagt caaagctttg
     6721 cggcgattat acctgaacca taataaaagg cggatttttc ggcgtgagcg ttgtaagtaa
     6781 aagccatacg ctttgtgaga cattgccgat agtctttatg cgaaatagca gagaaaattc
     6841 tgcgatgcat gtcaaataag ctatataaat cagttaattg cttttatata aaactctgaa
     6901 aatgtgcaaa tactgatggc ggttgattgt ttgtttaaag caaaggcgta aagtagcacc
     6961 catagagcga ggacgctaac aggaacaatg actcaggatg agggtcagga gcgccaggag
     7021 gcgaagacag aggattgtca ggaagacaaa cgtccggaga cgtaattaaa cggaaatgga
     7081 atcaacacgg attgttccgg ctaatggaaa aacagggtgt gttggcggcc tgcaaggatt
     7141 gtaagacccg ttaagggtta tgagtcagga aaaaaggcga cagagtaatc tgtcgccttt
     7201 tttctttgct tgctttctgt tagattccgc cgcaaatcta tactgaataa aacggctaaa
     7261 agacgaacca ttatgaaacc atcatcttca aactcacgca gcaaaggtca tgcaaaagcg
     7321 cgtcgaaaaa cacgcgagga gctggatcag gaagctcgtg accgtaagcg tcagaaaaaa
     7381 cgtcgtggtc atgcgccggg cagccgcgca gcgggcggta acacctcgtc aggcagcaaa
     7441 ggccagaacg caccaaaaga tccacgtatt ggcagtaaaa cccctattcc attgggcgtg
     7501 actgaaaaag tcaccaaaca gcacaaaccg aagagtgaga aacctatgct ttcaccgcag
     7561 gcggagttgg aattactgga aacggatgag cgtctggatg cgctgctgga acgtctggaa
     7621 gcaggcgaaa ccctgagcgc cgaagagcaa tcctgggtgg atgctaaact ggatcgtatt
     7681 gatgagttga tgcagaaact cggcctctct tatgacgatg acgaagaaga ggaagaagac
     7741 gagaagcaag aagacatgat gcgtctgctg cggggcaact aacggattgc cgccgtgggc
     7801 cttcccgttc tgctgataac ccttccggtt atatgttatc tggtgtggtt attcgttaaa
     7861 ctacagcggt tgtcgcggcg acaaaagtgg ctgcgcaacc ggctgatgac ccgaaacggg
     7921 catccgccgg tacgccgtag ccgccagaga cgccatcgga aggagtgagc atgtctgtac
     7981 agcaaatcga ctgggatctg gccctgatcc agaaatataa ctattccggg ccacgataca
     8041 cctcgtaccc gaccgcgctg gagttttcag aagacttcgg cgaacaggcg tttttacaag
     8101 ccgtggcgcg ctatcctgag cgtccattat ctctctacgt acatattccg ttctgccata
     8161 agctttgtta cttctgcggt tgcaataaga tagttactcg ccagcagcac aaggccgatc
     8221 agtatctgga cgcgctggag caagaaatcg tccatcgtgc accgcttttt gccgggcgca
     8281 aggtgagcca gctgcactgg ggcggtggta cgccgacgta tctgaacaaa gcgcaaatca
     8341 gccgtctgat gaagctgctg cgcgaaaact tccagttcaa tgccgatgcg gagatttcga
     8401 tcgaagtcga tccgcgcgaa atcgaactgg atgtactcga tcatttacgc gccgagggct
     8461 ttaatcgcct gagcatgggc gtgcaggact tcaacaaaga agtgcaacgt ctggttaacc
     8521 gcgagcagga tgaagagttc atctttgcac tgcttaacca tgcgcgtgag attggcttta
     8581 cctccaccaa catcgacctg atttacggtc tgccgaaaca gacgccggaa agttttgcct
     8641 ttaccctgaa acgtgtggcg gagctgaacc ccgatcgtct gagcgtcttt aactacgcgc
     8701 atttgccgac catttttgct gctcagcgca aaatcaaaga tgctgacctg ccgagtccgc
     8761 agcaaaaact cgatatcctg caggaaacca ttgccttcct gacgcaatcg ggctatcagt
     8821 ttatcgggat ggatcacttt gcccgcccgg atgacgagct ggcggtggcc cagcgtgaag
     8881 gcgtgctgca tcgtaacttc cagggctaca ccactcaggg cgataccgat ctgctgggga
     8941 tgggcgtttc cgccatcagt atgattggcg actgctacgc gcagaaccag aaagagttga
     9001 agcactacta tcagcaagtg gatgaacaag gcaacgcgct gtggcgtggt attgcgctaa
     9061 cgcgtgatga ctgtattcgc cgcgatgtga ttaagtcgct catctgcaac ttccgtctgg
     9121 attacgctcc cattgagcaa cagtgggatt tgcacttcgc tgattacttt gcggaagatc
     9181 tcaagctgct cgccccgtta gcaaaagatg ggctggtgga tgtggatgag aaggggattc
     9241 aggtgacggc gaaaggtcgc ttgctgatcc gcaacatttg catgtgcttt gatacctatc
     9301 tgcgccagaa agcgcggatg cagcagttct cacgggtgat ttaaatagtg aatggcgctt
     9361 cgtttacaaa gtagaaaacg aaagcgccat caatgtgctg agaacaagat tgcctgatgc
     9421 gctgggcaac aaaacctgta gaaattattg cttttgtagg ccagataagg cgtttacgcc
     9481 gcatctggca tctgagcatg atgcctgatg cgacgctggt cgcgtcttat caggcctacg
     9541 actttctccg catccggcat aaacaacgag cttcagctaa acagcccaat catcgcggca
     9601 cacagcacgg cagcaacggc agtttgcggt gtgtggctgt caactgcgcc actcgatacc
     9661 agattaatta ttgattccag cataatgact ctccccgttt tccgggcaag atcatactga
     9721 acttatcgga acagtaaagc gcaaaatacc agcaatttgc gctcaataat caatctttac
     9781 acacaagccg tgaatcactc cattcccagc tcttttaact tccgcgtcag agtgttacgc
     9841 ccccagccga gtagccgcgc cgcttcctgt ttatgcccct gcgtatgtcg caacgcggtc
     9901 gtcagtaacg tccgctccaa ctctggttgc gcttcagaca gcaagttttg atgaccggaa
     9961 cgtagcgccc gatctgccca ctgtgctaac agcgttgccc aactgtccgg ctgcatttgt
    10021 gaagtgcttt ccggtacggt tgattcaaac agttcgccag gcaaatcctg aatcaacact
    10081 tcctgtccgg cagccattac cgttagccag cggcaggtgt tttccagctg gcgcacgttg
    10141 cctggccacg ccagacgcgt cagagcggct tcagtttccg gatgcagcaa ctttgcttct
    10201 acgcccagct cgcgagcagc aacttgtaaa aaatggtgtg ccagacgggg aatatcttcc
    10261 cgacgctcac gcagcggcgg cagatgaaca cggatgacgt tcaggcggtg gaacagatcc
    10321 tcacggaact tgccttcctg cacccgctgt tcgagattct ggtgagtggc agcgataatc
    10381 cgcacatcca ctttcaccgg tgcatagccg ccaacgcgat aaaactgacc gtctgccagc
    10441 acgcgcagca aacgcgtctg cacatccagc ggcatatcgc caatttcatc gagaaataac
    10501 gtgccgccat cggcttgttc aaaacgcccc tgacgaatgg tattcgcgcc ggtaaacgcg
    10561 cctttctcgt gaccaaacag ttctgattcg atcaaatcct tcgggatagc cgccatattg
    10621 agcgcgataa acggcgcttt ggctcgcggg ctgtggcgat gcagggcatg agcgaccagt
    10681 tctttaccag tgccggattc gccgttgatc agcacgctaa tggaagaacg cgaaagtcga
    10741 ccgataatac ggaacacgtc ctgcatggct ggcgcttcgc cgatgatatc ggtcgttggg
    10801 ccgttaagct gaacattacg cggctgctgc tgttcctgat aatgactgat ggcgcgctca
    10861 accagcgcca cggcttcgtc gatatcaaac ggtttgggca gataatcaaa cgccccttgt
    10921 tgataggcgc tgacggcagc atccagatcg gaatgtgcgg tcataatgat gaccggaagc
    10981 attggatggc gctgtttaat ctgcttgagc agcgccagcc cgtccattcc cggcatacgg
    11041 atatctgaaa gcagtacatc cggcgttttg ctcgccaacg cctccagtac ttccgcgccg
    11101 ttctcaaatg tcgtacaggt taaacccgct ccagcgagcg cacgttcaag cacccaacgg
    11161 atggaactat cgtcatcgac tacccagact atccctcgtt gcataaacgt cacctttatt
    11221 tcctgatagg caggtaaacc gagaactcgg tatgacctgg ccaactggta aattcaattt
    11281 tgcctgaatg ctgatcaatc aaattacggg cgatggataa gccaagcccg gtgccacctt
    11341 cgcggccgct gaccatcggg taaaacagcg tatcctgcaa atgaggcgga atgcccggcc
    11401 cgttatcttc cacatcaatc cgcgccgcca gccgatagcg ctcgccgtgc aaggtcagtt
    11461 gaaacgctgt gcgggtacgc agaatgattt caccaccctc cggccccagc gcctgtagcg
    11521 cattgcgcac aatattcagc aagacctgtt caatttgatc cgggtcgtgc gccagttccg
    11581 gcaggctggg atcgtaatca cgaatcaacc gcacgttgtc cggcagttcc atcgacacca
    11641 gcgtcaccac gcgttcagcc actttgtgaa tactttcggt aacgcgcgta ccgggcagct
    11701 gcggccccaa cagacggtcg accagatttc gcagccggtc cgcctgttcg ataattactt
    11761 tggtatattc gagtagtgac gggtcaggta atgccttgct gagtagctgc gccgcaccac
    11821 gtaaaccgcc aagcggattt ttaatctcat gcgccaggcc gcgcactaaa tcacgggcag
    11881 caacctgctg ggcgtgctgt agctgttcct gacttaagcg gcgctggtta tccatcggtg
    11941 ccatctccag caggatcatg ccgtccggca tacgctgggc cgtcacagaa aggatatgcg
    12001 aacgcccgtc gatgaccagc gtcacttcgt tatcggtaaa accttgcccc gcctccagac
    12061 tttcttgcat cagctcgata tttaatgaga agtagctcaa cagttccggt aacggtgtac
    12121 caaacaattt gcgggagctt tgggcgagca gttgttgcgc ggcggggttg gcgtaatgga
    12181 tcgccaggtt gtcatcgatt aacaaaatac tgttaatcag cgagttgagg atctgcccag
    12241 catcgggctg cgtgcctgtt gccataaagc agtctcctga acaggttgca ccattttagt
    12301 gcattatagc tttttacgga taaaaagcgc gaagcatcag agaattgacg gagaaaaaag
    12361 cccatgcaga gatgggctga aagtttccac ggcaactaaa tcccggcgtt gttgcgccgg
    12421 gtagtacaac ttcaactatt agacgctgta gtacagctca aactctaccg gatgcggagt
    12481 catacgcaca cggtcatctt cttcgcgacg cagagcgatg tacgcatcga tcgcttcatc
    12541 agtgaacacg ccaccggctt tcaggaactc gcggtccaga tccagttcgt tcagtgcttc
    12601 ttccagagaa ccagcaacct gtgggatctc tttcgcttct tccggcggca ggtcatacag
    12661 gtttttgtcc atcgcttcgc ccggatggat cttgttcttg ataccgtcaa gaccggccat
    12721 cagcagggca gcaaagcaca ggtacgggtt agccgccggg tccgggaaac gtacttcgat
    12781 acgacgtgct ttcggagaag aaaccaccgg aatacggata gacgcagaac ggttacgcgc
    12841 agagtaagcc agcattaccg gtgcttcgta gcccgggacc agacgcttat aagagttggt
    12901 ggtcgggttt gccagggcgt taattgcttt cgcgtgtttg attacgccgc caatgtagta
    12961 cagcgcctgt tcagacagac ctgcgtattt gtcgccagca aacaggttaa cgccgttttt
    13021 agacagcgac atgtggcagt gcataccgga accgttatca ccgaacatcg gttttggcat
    13081 aaaggtcgca gttttaccga agcggtgcgc tacgttgtgc acaacatatt tgtagatctg
    13141 aatttcgtca gcttttttgg tcatggtatt gaagcgggta gccacttcgt tctgaccagc
    13201 agtcgctact tcgtggtgat gggcttcaac caccagaccc atctgttcca tcaccagaca
    13261 catttcagaa cgaatatcct gagccgagtc taccggtgga accgggaagt aaccgccttt
    13321 cactgccgga cggtgacctt tgttaccacc ttcgtattgg gtggaggagt tccatgcgcc
    13381 ttcgatatcg tcgatagcaa cgtgggaacc ggagatagat gatccgaaac ggatgtcatc
    13441 gaacaggaag aattcaggtt ctggcccgaa cagtacggtg tcggcaatgc cagtggaacg
    13501 caggtaatct tcggcgcgct tcgcaatgga gcgcgggtca cggtcatagc cttgcagggt
    13561 gccaggttca aggatgtcgc aacggataat cagggtggag tcggcgaaga acgggtcaat
    13621 cactgcggtg gatgcgtctg gcatcagcac catgtcggat tcgttaatgc ctttccagcc
    13681 gccaatcgag gagccgtcaa acattttgcc ttcttcgaag aattcagcat tcacctgatg
    13741 agcagggata gtgacgtgct gttctttacc tttggtatcg gtgaagcgca aatcaacaaa
    13801 cttcacttcg tgctcgttca gcatcgtcag tacgtgttca gcggacatac tttaactctc
    13861 ctggattggt catggtcgtc gtggtaacga aatctgcaat tattttggcc gtgtcgccgt
    13921 aaaaaagata aagcgaaaac tgtgccaact tttaaattgc ccctaaaagg cgttatcatg
    13981 cttaacatcg tgcaaaaggg ctgcaccatg atgtgaatgt tgcaccaata tagtgcttca
    14041 atggaaacat taagcaccat attggtgcaa tggcctttgg ataacccttt ttatgctccg
    14101 tgaaagcgat cacaaaggga ctctgcaata cttgtttgcg gaggatgttt gtgatcctgt
    14161 tttgtagtgc gattaatccg tgtacaataa cgcgctattt ctaatgcctg aggcaaagtt
    14221 gtgatcgaaa aattgcgtaa tatcgccatc atcgcgcacg tagaccatgg taaaaccacc
    14281 ctggtagaca agctgctcca acaatccggt acgttcgact ctcgtgccga aacccaagag
    14341 cgcgtgatgg actccaacga tttggagaaa gagcgtggga ttaccatcct cgcgaaaaac
    14401 accgctatca aatggaatga ttaccgtatc aacatcgttg ataccccggg gcacgccgac
    14461 ttcggtggtg aagttgaacg tgtaatgtcc atggtagact cagtgctgct ggtggttgac
    14521 gcatttgacg gcccgatgcc gcaaacgcgc ttcgtaacca aaaaagcgtt tgcttacggc
    14581 ctgaagccga ttgttgttat caacaaagtt gaccgccctg gcgcgcgtcc tgattgggtt
    14641 gtggatcagg tattcgatct gttcgttaac ctcgacgcga ccgacgagca gctggacttc
    14701 ccgatcgttt acgcttctgc gctgaatggt atcgcgggtc tggaccacga agatatggcg
    14761 gaagacatga ccccgctgta tcaggcgatt gttgaccacg ttcctgcgcc ggacgttgac
    14821 cttgacggtc cgttccagat gcagatttct cagctcgatt acaacagcta tgttggcgtt
    14881 atcggcattg gccgcatcaa gcgcggtaaa gtgaagccga accaacaggt tactatcatc
    14941 gatagcgaag gcaaaacccg caacgcgaaa gtcggtaaag tgctgggcca cctcggtctg
    15001 gaacgtatcg aaaccgatct ggcggaagct ggcgatatcg tggcgatcac gggtcttggc
    15061 gaactgaaca tttctgacac cgtttgcgac acgcaaaacg ttgaagcgct gccggcactc
    15121 tccgttgatg agccgaccgt ttctatgttc ttctgcgtta acacctcgcc gttctgcggt
    15181 aaagaaggta agttcgtaac gtctcgtcag atcctggatc gtctgaacaa agaactggta
    15241 cacaacgttg cgctgcgcgt agaagaaacc gaagacgccg atgcgttccg cgtttctggt
    15301 cgtggcgaac tgcacctgtc tgttcttatc gaaaacatgc gtcgtgaagg tttcgaactg
    15361 gcggtatccc gtccgaaagt aatcttccgt gaaatcgacg gtcgtaaaca agagccgtat
    15421 gaaaacgtga cgctggacgt tgaagaacag catcagggtt ctgtgatgca ggcgctgggc
    15481 gaacgtaaag gcgacctgaa aaacatgaat ccagacggta aaggccgcgt acgtctcgac
    15541 tacgtgatcc caagccgtgg tctgattggc ttccgttctg agttcatgac catgacttcc
    15601 ggtactggtc tgctgtactc caccttcagc cactacgacg acgtacgtcc gggcgaagtg
    15661 ggtcagcgtc agaacggtgt actgatctct aacggtcagg gtaaagcggt cgcgttcgcg
    15721 ctgttcggtc tgcaggatcg cggtaagctg ttcctcggtc acggtgcaga agtttacgaa
    15781 ggtcagatta tcggtattca tagccgctct aacgacctga ctgtaaactg cctgaccggt
    15841 aagaaactga ccaacatgcg tgcttccggt actgacgaag ccgttgttct ggttccgcct
    15901 atccgcatga ctctggaaca agctctggag ttcatcgatg atgacgaact ggtagaagtg
    15961 actccgacct ctatccgtat tcgtaaacgt cacctgacgg aaaacgatcg tcgtcgcgcc
    16021 aaccgcgcac cgaaagacga ttaatttcgt tttttagtta taaaaaacct gccatcgctg
    16081 gcaggttttt tgcttttgta ggcctgataa gatgcgccag catcgcatca ggcgtcatct
    16141 gaaaccctgc gcatcaagaa aatccgcaat agcatctgtg ttgttgtgac caataacgcg
    16201 gtcagcactg acttttgcca gcgaactgcc attgcccatc gcaatccctt tgcctaccat
    16261 ccgcagcatc cccgcatcat tatcgttatc gccaaaggcg atgatttcat ccagcacgat
    16321 attttgctgt cgtgcatacc aggccagact tttgcctttc tcacaccccg cctgggtgat
    16381 atccagttga tgatgccagg accagctaca ggctagcgat aattcttgcc gggcaaattc
    16441 ctctgcctgg cgcaataacg aagccttgcg gtgcaccagg ctaatctgca aaacaaaatc
    16501 atcatacgta taaatatgtg gctgcaatgc ctgttgtgaa aaccagcgtc gtagctgttc
    16561 caccttttgg gtatccagcg gcagcggacg caatatttgc cgctgtcgcg gatgataaag
    16621 ataactgccg ttacagcaaa tcatcggctc ggttaactgc aattgctgat aatagggcag
    16681 ggcttcgctg tgcgaacgtc cggtggcgag gataatcttc acacctgcct gttgcgcgct
    16741 ttgcagtgcc gaaacagacg caggggaaat cattttcttg ctgttcagca atgtgccgtc
    16801 taaatcgagc gcgattaacc ggcagatcat aacgagaaga tccgaaagca gcgttcagca
    16861 tcaaattgtg agagggccgg aatatcctga cgcagatgat aagccagata acagtggcac
    16921 tgccgggcca tacaggctgg agatgaaagt tgctgctgat ataaattgcc gattttaatt
    16981 ttgctgatat tacaggcgaa gagatcgcca tcagcattca taaacacgct ctttttgccg
    17041 ccgatacaaa actcgacatt cgcaggccag aggctggttt ccagatgata aagcgggtcc
    17101 agcatctgaa actggctatt tctttcgtcg ctggtgggcc ttttatcgcg ctcattggcg
    17161 tttagccaga aatagatatc ggcaggaaga tgcgcgcgta accactggaa tgtgtcgtag
    17221 ttgtctacgc tggcaacggc ccccacagaa caagtaatcc ccgcgtcctt aattgccagt
    17281 atttgtttaa ggaaaacatc tttactaacc tgggaaggat gaaacgaaca ccatagccgc
    17341 agctttgcca gatccccctg attatcctgc atagtcgcta tcaacgagga taaattaaac
    17401 gaggcgttgg tctgaatacc taccgcctgc acatgggaat agcggcttat tttcgccatc
    17461 gccgccatat aataacgata gcgcaatgct tcgccgtagg gtgtaatcaa cacatttaac
    17521 ggtgaaccca gcgccggtaa atgctcaacc atgcgccata atgccgcttc atcctgctgt
    17581 ttatcattgc ggtcttgttt atgaaaaggg caataaccac agcgataatt acacgacttt
    17641 atctcgccgc gataaatcag cgtctggatc tgcttgagcg tcatcgttta tgcgtctcca
    17701 gcctgcgaac ttccggggag ataaacagcg ggccaagctg gtccgaaagc gctaaaccct
    17761 gcgcggtgag cagaatacga ttatcctgct ggtggcaata atcttgtttg ataaaatcgc
    17821 ccagcagggg aaaatcgctt aatacctcag aggagaactg gcgctgataa tcacgtaacg
    17881 aaagcccttt atagaaaaag agattcttga taacaaaacg ccgcttcatc tctgcttgcg
    17941 aaagcacata gccgtggtta ataagggttt tatcttgtcg ggcgataaaa tccgcgacaa
    18001 tttgtcgcga tgcaggctgg ttttgcgacc acggcgtgca gtaatgtaaa ttgccaaggt
    18061 aactgcgccc gcccgcgcca agcgccagcg aattttcaaa gccacaactt tcaaccgccg
    18121 aatcattatt cacccgcaca aaacggcgca ttgacgtttg cgtataacct tcatgcaata
    18181 agcgatcgcg ggcttcaata tagaggctat acatatccgg ctggcgaggc atgttataca
    18241 gtgggtacag aaacagttcg tcaggttgat aatctaatgc ctgattaagc gatgccatta
    18301 aacttgctgc tgtttgacca ggaataccgt aaataatatc gatattgagt atcgggaaat
    18361 tgcccctgcg cagcagctcc agcgcccgat gggcatttgt cgcgctatgg cggcggtgta
    18421 atgtggcaag ttccagatcg ttaaaactct gcacaccaat actgacacgg ttaaccgcaa
    18481 gctggcgcaa taacgcgact ttttcggcgg tggtatcgga aggcgatgtt tcaattgcct
    18541 taaaaatatg cgcatcgacc tgtaattcgt caaatactcc gttaaacaac cgcaacagtt
    18601 gcccgacatt aagcaacagt ggcgtaccgc cgccaatggt aaaactgtcc cagtctacag
    18661 gcgcaagttg catttgccgg gcctggacaa taatcgcctc tatgtagttg tcgataaagg
    18721 cattgtttgc tcccgtgcag gtaaaaagat tacaaaaccc gcagcggctc tggcaaaagg
    18781 gcatatgaat atagagatgt gttttatgct cgtaaatacg cgacttcaca tccgcaaaag
    18841 caatattgtt taattcccga taagcggtct tatgcgggta actgtacata tattgctgat
    18901 aaatggattc attattcatg agctgtgccg tctaatacaa agtgaaaata gggtacggta
    18961 ttcacaatcg gatggttaaa actgtggaaa tatttaccgt cttccccgta gcaggtgcca
    19021 tgatcggaac agagaataac taacgtctct cgtccggttt gccggaaggt gtcgaaaagt
    19081 ttttcgattc tcgcatcaat ataatgcagg gcagcggcgt gagtttctac cgtatcgcca
    19141 ggcttggcat tttcaatata aaaatgattc ggataatgaa tggtgtcgat attgatatac
    19201 atcatcagcg gctgttcagc gttcaccttt ttattaatta aggtgagctg attatccatg
    19261 ctctctttta ccgtgcagga gaaattagga taccagtaac tctctttaaa catcgccggg
    19321 aacactttcc ccatccctga acggttatta aaaaaggaga cgccacccac gcagatagtg
    19381 cggtaacctt tgttttccag ccctttaatc cacgtctctt cgctgaatgc gaacgcattt
    19441 tttggcccta aacgccctaa gccaatatct ttcgggaaaa agagcattga atggcccggt
    19501 gcggcttcca gcggcttagg cataaaacca gaaaacatcg aatgatgcga aggccaggta
    19561 aaattgccag cggcttcgca ctttatccag cgaccatagc ggttaatgtt cggcgtattg
    19621 cccgcctctt gttcctgaaa cgcaatatca aaacgcaggg aatcaagcac tacaaacaga
    19681 acattcgcct ccctggctat caaatcattt aaattgattt cgccatcgca ggaatggatt
    19741 gccgtgcggg tattttccgg tacttcgtct gttacgttat acatggtgtt ctctcattac
    19801 ctgaatctgg cgttgataaa ttttgttttg ttcgcaggtg tcctgataaa taagatcgcc
    19861 ctggccgtta atttcgataa tatagggtgt taacttttgc gtgagtaata cgtcaagccc
    19921 ggcaatgtgt acgtccgggt agagtttcat ggcgttgaga caaagcgtgt caatttcagc
    19981 cactttttct gcgggtaaat taagatcggc aaaacggata gcttcatttt gtaaatgtaa
    20041 attggtgatc ggctgtgatg atgttctgac aacccgccag acgatttcgc cattaacgta
    20101 tactattcgt aaatcgtagc ttttattgcc cactctggct tttgccagcc agcattcgat
    20161 aatattttct tgttgtaaaa tagcattcac aatcaactta atatcatcgc tgttttcata
    20221 gcggataata tgtttactgt tcaccagcct gtcacctgca acctggatgg cgcaataaag
    20281 tacctgacgg ttatcgccgg gatgtaaatt tagagccagc accccggctg cgcctgatcc
    20341 gagatttggc ttaataaaca cgcgataaac cttttcgctg cgcatacagg cgatcaattg
    20401 atcgtagcta cgggcatcat ccgctaatat cggcggtgtc gggatcgcgt gttcgattaa
    20461 tcgttgctta cagtagcgct tatccagaag atgaataata ccttctggcg agttaataaa
    20521 acggatttcc cttctggtag ccattttgtg taaaaaacta atatagtttt ggctaaccgt
    20581 attaattaag cgaatatctg tttcctgatg taagggggga tcaattttta ccatgccttt
    20641 atttagcggc agggtaagtg cctgatcata gttcaccacg ttgatatgtt cctgtaagcg
    20701 tgacgctgcc tggcaaaaat aaaatgtgcg tttgctttca ggatgaccaa ttagcgtaat
    20761 cacgaagaat tccttttctg tgataaataa tgggagagat gactctctcc caataaattt
    20821 catttattcg gtaaacatcg ggtgcatata aacttcgtca tcatagactt caggtgttag
    20881 cgcttctgat aattcaacag tacatgtcag tgttttttgc agttttttct gcatctgttc
    20941 tgtcaggtaa tgatgataca aatccagcag tttcagatgg ctaaggcgat cggcatgttt
    21001 gagaagatgc tctgcacctt cgtcggtaag cgtaccgcag gagagtgcca acacttccag
    21061 ttgcggcaga atgtcgcttt ccagcacgcg gcggacgatt tcgttttgct cttcgctgtt
    21121 caccagacca agatgcgtca ggcttgggaa gagggatttc gacgccagtt tcatcacgat
    21181 atccagcgat gcatcaaaac cataatcctc aacgccaata taaacgataa gtgtttttaa
    21241 cgcaggcagt tgagagtttt gcaatgacgc aaacacatta cacggtgtac cgccagagat
    21301 gatttccagg tgctccagtt tgtcgtgggc gatttctccc agttccaggt cttgagtacc
    21361 tttaatcgtc agctttttga ggttcggcag tgcggcatac agacgagaat aatcgccttg
    21421 ttttatccac gaaatttcac attcttcgct ttccatatcg ccgataaaca gggactcaag
    21481 atgagcaaag cgttctgcat gttcagcaaa catgtcgatt atcggttgac aactttcctc
    21541 gtagcattcc ccccaacgac taatgaccaa agagcga
//
LOCUS       DADXDL010000083        21539 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.083, whole genome shotgun sequence.
ACCESSION   DADXDL010000083 DADXDL010000000
VERSION     DADXDL010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21539)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21539)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21539
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.083"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            89..241
                     /gene="hokA"
                     /locus_tag="IRB70_003611"
     CDS             89..241
                     /gene="hokA"
                     /locus_tag="IRB70_003611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001135724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokA"
                     /protein_id="HBC0633476.1"
                     /translation="MPQKYRLLSLIVICFTLLFFTWMIRDSLCELHIKQENYELAAFL
                     ACKLKE"
     gene            complement(430..642)
                     /gene="cspA"
                     /locus_tag="IRB70_003612"
     CDS             complement(430..642)
                     /gene="cspA"
                     /locus_tag="IRB70_003612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA chaperone/antiterminator CspA"
                     /protein_id="HBC0633477.1"
                     /translation="MSGKMTGIVKWFNADKGFGFITPDDGSKDVFVHFSAIQNDGYKS
                     LDEGQKVSFTIESGAKGPAAGNVTSL"
     gene            complement(923..1213)
                     /locus_tag="IRB70_003613"
     CDS             complement(923..1213)
                     /locus_tag="IRB70_003613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator"
                     /protein_id="HBC0633478.1"
                     /translation="MEYKDPMHELLSSLEQIVFKDETQKITLTHRTTSCTEIEQLRKG
                     TGLKIDDFARVLGVSVAMVKEWESRRVKPSSAELKLMRLIQANPALSKQLME"
     gene            1647..2357
                     /locus_tag="IRB70_003614"
     CDS             1647..2357
                     /locus_tag="IRB70_003614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418010.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3053 domain-containing protein"
                     /protein_id="HBC0633479.1"
                     /translation="MATGKSCSRWFAPLAALLMVVSLSGCFDKEGDQRKAFIDFLQNT
                     VMRSGERLPTLTADQKKQFGPFVSDYAILYGYSQQVNQAMDSGLRPVVDSVNAIRVPQ
                     DYVTQSGPLREMNGSLGVLAQQLQNAKLQADAAHSALKQSDDLKPVFDQAFTKVVTTP
                     ADALQPLIPAAQTFTQQLVMVGDYIAQQGTQVSFVANGIQFPTSQQASEYNKLIAPLP
                     AQHQAFNQAWTTAVTATQ"
     gene            complement(2407..3381)
                     /gene="ghrB"
                     /locus_tag="IRB70_003615"
     CDS             complement(2407..3381)
                     /gene="ghrB"
                     /locus_tag="IRB70_003615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312465.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrB"
                     /protein_id="HBC0633480.1"
                     /translation="MKPSVILYKALPDDLLQRLQEHFTVHQVANLSPQTVEQNAAIFA
                     EAEGLLGSNENVDAALLEKMPKLRATSTISVGYDNFDVDALTARKILLMHTPTVLTET
                     VADTLMALVLSTARRVVEVAERVKAGEWTASIGPDWYGTDVHHKTLGIVGMGRIGMAL
                     AQRAHFGFNMPILYNARRHHKEAEERFNARYCDLDTLLQESDFVCLILPLTDETHHLF
                     GAEQFAKMKPSAIFINAGRGPVVDENALIAALQKGEIHAAGLDVFEQEPLSVDSPLLS
                     MANVVAVPHIGSATHETRYGMAACAVDNLIDALQGKVEKNCVNPHVAD"
     gene            complement(3485..4144)
                     /locus_tag="IRB70_003616"
     CDS             complement(3485..4144)
                     /locus_tag="IRB70_003616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="OmpA family lipoprotein"
                     /protein_id="HBC0633481.1"
                     /translation="MKKRVYLIAAVVSGALAVSGCTTNPYTGEREAGKSAIGAGLGSL
                     VGAGIGALSSSKKDRGKGALIGAAAGAALGGGVGYYMDVQEAKLRDKMRGTGVSVTRS
                     GDNIILNMPNNVTFDSSSATLKPAGANTLTGVAMVLKEYPKTAVNVIGYTDSTGGHDL
                     NMRLSQQRADSVASALITQGVDASRIRTQGLGPANPIASNSTAEGKAQNRRVEITLSP
                     L"
     gene            4297..6630
                     /gene="bisC"
                     /locus_tag="IRB70_003617"
     CDS             4297..6630
                     /gene="bisC"
                     /locus_tag="IRB70_003617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418007.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin sulfoxide reductase"
                     /protein_id="HBC0633482.1"
                     /translation="MANSSSRYSVLTAAHWGPMLVETDGETVFSSRGALATGMENSLQ
                     SAVRDQVHSNTRVRFPMVRKGFLASPENPQGIRGQDEFVRVSWDEALELIHHQHKRIR
                     EAYGPASIFAGSYGWRSNGVLHKASTLLQRYMALAGGYTGHLGDYSTGAAQAIMPYVV
                     GGSEVYQQQTSWPLVLEHSDVVVLWSANPLNTLKIAWNASDEQGLSYFSALRDSGKKL
                     ICIDPMRSETVDFFGDKMEWVAPHMGTDVALMLGIAHTLVENGWHDEAFLARCTTGYA
                     VFASYLLGESDGIAKNAEWAAEICGVGAAKIRELAAIFHQNTTMLMAGWGMQRQQFGE
                     QKHWMLVTLAAMLGQIGTPGGGFGLSYHFANGGNPTRRAAVLSSMQGSLPGGTDAVDK
                     IPVARIVEALENPGGAYQHNGMDRHFPDIRFIWWAGGANFTHHQDTNRLIRAWQKPEL
                     VVISECFWTAAAKHADIVLPATTSFERNDLTMTGDYSNQHLVPMKQVVPPRYEARNDF
                     DVFAELSERWEKGGYARFTEGKSELQWLETFYNVARQRGASQQVELPPFAELWEANQL
                     IEMPENPDSERFIRFADFRRDPQAHPLKTASGKIEIFSQRIADYAYPDCPGHPMWLEP
                     DEWQGNAEPEQLQVLSAHPAHRLHSQLNYSSLRELYAVANREPVTIHPDDAQARGIQD
                     GDTVRLWNARGQILAGAVISEGIKPGVICIHEGAWPDLDLTADGICKNGAVNVLTKDL
                     PSSRLGNGCAGNTALAWLEKYNGPELTLTAFEPPASS"
     gene            complement(6599..7039)
                     /locus_tag="IRB70_003618"
     CDS             complement(6599..7039)
                     /locus_tag="IRB70_003618"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBC0633483.1"
                     /translation="MIREAQRSELPAILELWLESTTWGHPFIKANYWRDCIPLVRDAY
                     LANAQNWVWEEDGKLLGFVSIMEGRFLAAMFVAPKAVRRGIGKALMQYVQQRHPHLML
                     EVYQKNQPAIDFYQAQGFHIVDCAWQDETQLPTWIMSWPVVQTL"
     gene            complement(7036..7599)
                     /gene="tag"
                     /locus_tag="IRB70_003619"
     CDS             complement(7036..7599)
                     /gene="tag"
                     /locus_tag="IRB70_003619"
                     /EC_number="3.2.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBC0633484.1"
                     /translation="MERCGWVSQDPLYIAYHDNEWGVPETDSKKLFEMICLEGQQAGL
                     SWITVLKKRENYRASFHQFDPVKVAAMQEEDVERLVQDAGIIRHRGKIQAIIGNARAY
                     LQMEQNGEPFADFVWSFVNHQPQVTQATTLSEIPTSTPASDALSKALKKRGFKFVGTT
                     ICYSFMQACGLVNDHVVGCCCYPGNKP"
     gene            7757..8455
                     /locus_tag="IRB70_003620"
     CDS             7757..8455
                     /locus_tag="IRB70_003620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312460.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBC0633485.1"
                     /translation="MIIKKSGGRWQLSLLVSVVISAFFLNTAYAWQQEYIVDTQPGHS
                     TERYTWDSDHQPDYNDILSQRIQSSQRALGLEVNLAEETPVDVTSSMSMGWNFPLYQQ
                     VTTGPVAALHYDGTTTSMYNEFGDSTTTLTDPLWHASVSTLGWRVDSRLGDLRPWAQI
                     SYNQQFGENIWKAQSGLSRMTATNQNGNWLDVTVGADMLLNQNIAAYAALSQAENTTN
                     NSDYLYTMGVSARF"
     gene            8684..9892
                     /locus_tag="IRB70_003621"
     CDS             8684..9892
                     /locus_tag="IRB70_003621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633486.1"
                     /translation="MTPSNYQRTRWLTLIGTIITQFALGSVYTWSLFNGALSAKLGAP
                     VSQVAFSFGLLSLGLAISSSVAGKLQERFGVKRVTMASGILLGLGFFLTAHSNNLMML
                     WLSAGVLVGLADGAGYLLTLSNCVKWFPERKGLISAFAIGSYGLGSLGFKFIDTHLLE
                     TVGLEKTFVIWGAIVLVMIVFGATLMKDAPKQEVKTSNGVVEKDYTLAESMRKPQYWM
                     LAVMFLTACMSGLYVIGVAKDIAQSLAHLDAISAANAVTVISIANLSGRLVLGILSDK
                     IARIRVITIGQVISLVGMAALLFAPLNAVTFFAAIACVAFNFGGTITVFPSLVSEFFG
                     LNNLAKNYGVIYLGFGIGSICGSIIASLFGGFYVTFYVIFALLILSLALSTTIRQPEQ
                     KMLREAHGSL"
     gene            10216..11907
                     /gene="eptB"
                     /locus_tag="IRB70_003622"
     CDS             10216..11907
                     /gene="eptB"
                     /locus_tag="IRB70_003622"
                     /EC_number="2.7.8.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418002.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kdo(2)-lipid A phosphoethanolamine
                     7''-transferase"
                     /protein_id="HBC0633487.1"
                     /translation="MRYIKSITQQKLSFLLAIYIGLFMNGAVFYRRFGSYAHDFTVWK
                     GISAVVELAATVLVTFFLLRLLSLFGRRSWRILASLVVLFSAGASYYMTFLNVVIGYG
                     IIASVMTTDIDLSKEVVGLNFILWLIAVSALPLILIWNNRCRYTLLRQLRTPGQRIRS
                     LAVVVLAGIMVWAPIRLLDIQQKKVERATGVDLPSYGGVVANSYLPSNWLSALGLYAW
                     ARVDESSDNNSLLNPAKKFTYQAPQNVDDTYVVFIIGETTRWDHMGIFGYERNTTPKL
                     AQEKNLAAFRGYSCDTATKLSLRCMFVRQGGAEDNPQRTLKEQNIFAVLKQLGFTSDL
                     YAMQSEMWFYSNTMADNIAYREQIGAEPRNRGKPVDDMLLVDEMQQSLGRNPDGKHLI
                     ILHTKGSHFNYTQRYPRSFAQWKPECIGVDSGCTKAQMINSYDNSVTYVDHFISSVID
                     QVRDKKAIVFYAADHGESINEREHLHGTPRELAPPEQFRVPMMVWMSDKYLENPVNAQ
                     AFAQLKKEADMKVPRRHVELYDTIMGCLGYTSPDGGINENNNWCHIPQAKEAAAN"
     gene            11999..12075
                     /locus_tag="IRB70_003623"
     tRNA            11999..12075
                     /locus_tag="IRB70_003623"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:12033..12035,aa:Pro,seq:cgg)
     gene            12239..13587
                     /locus_tag="IRB70_003624"
     CDS             join(12239..12719,12719..13587)
                     /locus_tag="IRB70_003624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558234.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBC0633488.1"
                     /translation="MKHPFEVKLAAVNHYLAGHAGIISTAKLFQLSHTSLSHWINLFL
                     LHGPLALDCRHRRSYSPEDKLCVVLYALGHSESLPRVAARFNIPSHNTVKNWIKGYHK
                     SGDEAFIRRRKEKSMTRSDDTHENEANMTPEEMKNELRYLRAENAYLKAMQEHLLEKK
                     PPGAGEKAKVIQNLRCGHCQSDLLKAAGLARSTLYYQLSLQKAKDKYADVKQLIASIF
                     HEHRGCYGYRRIHCELQKRGLKFSGKTVRKLMQQLGLKSPVRLKKYRSYRGNMGLAAE
                     NILQRQFKAKAPCEKWVTDITEFRAGGQKLYLSPILDLFNGEIVAWETACRPTEELVK
                     RMLNKGLESLAEGEKPLLHSDQGWHYRIKSYQSALADRGLVQSMSRKGNCLDNAVMEN
                     FFGHLKEEMYYRRDYRSVEELENAVSEYITYWNQKRIKLSLGGLSPVEYRTEYQKTG"
     gene            14255..15862
                     /gene="dppA"
                     /locus_tag="IRB70_003625"
     CDS             14255..15862
                     /gene="dppA"
                     /locus_tag="IRB70_003625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter substrate-binding
                     protein DppA"
                     /protein_id="HBC0633489.1"
                     /translation="MRISLKKSGMLKLGLSLVAMTVAASVQAKTLVYCSEGSPEGFNP
                     QLFTSGTTYDASSVPLYNRLVEFKIGTTEVIPGLAEKWEVSEDGKTYTFHLRKGVKWH
                     DNKEFKPTRELNADDVVFSFDRQKNAQNPYHKVSGGSYEYFEGMGLPELISEVKKVDD
                     NTVQFVLTRSEAPFLADLAMDFASILSKEYADAMMKAGTPEKLDLNPIGTGPFQLQQY
                     QKDSRIRYKAFDGYWGTKPKIDTLVFSITPDASVRYAKLQKNECQVMPYPNPADIARM
                     KQDKSINLMEMPGLNVGYLSYNVQKKPLDDVKVRQALTYAVNKDAIIKAVYQGAGVSA
                     KNLIPPTMWGYNDDVQDYTYDPEKAKALLKEAGLEKGFSIDLWAMPVQRPYNPNARRM
                     AEMIQADWAKVGVQAKIVTYEWGEYLKRAKDGEHQTVMMGWTGDNGDPDNFFATLFSC
                     AASEQGSNYSKWCYKPFEDLIQPARATDDHNKRVELYKQAQVVMHDQAPALIIAHSTV
                     FEPVRKEVKGYVVDPLGKHHFENVSIE"
     gene            16013..17032
                     /gene="dppB"
                     /locus_tag="IRB70_003626"
     CDS             16013..17032
                     /gene="dppB"
                     /locus_tag="IRB70_003626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005133865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppB"
                     /protein_id="HBC0633490.1"
                     /translation="MLQFILRRLGLVIPTFIGITLLTFAFVHMIPGDPVMIMAGERGI
                     SPERHAQLLAELGLDKPMWQQYLHYIWGVMHGDLGISMKSRIPVWEEFVPRFQATLEL
                     GVCAMIFATAVGIPVGVLAAVKRGSIFDHTAVGLALTGYSMPIFWWGMMLIMLVSVHW
                     NLTPVSGRVSDMVFLDDSNPLTGFMLIDTAIWGEDGNFIDAVAHMILPAIVLGTIPLA
                     VIVRMTRSSMLEVLGEDYIRTARAKGLTRMRVIIVHALRNAMLPVVTVIGLQVGTLLA
                     GAILTETIFSWPGLGRWLIDALQRRDYPVVQGGVLLVATMIILVNLLVDLLYGVVNPR
                     IRHKK"
     gene            17042..17944
                     /gene="dppC"
                     /locus_tag="IRB70_003627"
     CDS             17042..17944
                     /gene="dppC"
                     /locus_tag="IRB70_003627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010426221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter permease DppC"
                     /protein_id="HBC0633491.1"
                     /translation="MSQVTENKVISAPVPMTPLQEFWHYFKRNKGAVVGLVYVVIVLF
                     IAIFANWIAPYNPAEQFRDALLAPPAWQEGGSMAHLLGTDDVGRDVLSRLMYGARLSL
                     LVGCLVVVLSLIMGVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPS
                     IGNAALALTFVALPHYVRLTRAAVLVEVNRDYVTASRVAGAGAMRQMFINIFPNCLAP
                     LIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSAWWVVTFPGLAI
                     LLTVLAFNLMGDGLRDALDPKLKQ"
     gene            17955..18938
                     /gene="dppD"
                     /locus_tag="IRB70_003628"
     CDS             17955..18938
                     /gene="dppD"
                     /locus_tag="IRB70_003628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP-binding protein"
                     /protein_id="HBC0633492.1"
                     /translation="MALLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGS
                     GKSVSSLAIMGLIDYPGRVMAEKLEFNGQDLQRISEKERRNLVGAEVAMIFQDPMTSL
                     NPCYTVGFQIMEAIKVHQGGNKSTRRQRAIDLLNQVGIPDPASRLDVYPHQLSGGMSQ
                     RVMIAIAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVA
                     EAAHKIIVMYAGQVVETGDAHAIFHAPRHPYTQALLRALPEFAQDKERLASLPGVVPG
                     KYDRPNGCLLNPRCPYATDKCRAEEPALNMLADGRQSKCHYPLDDAGRPTL"
     gene            18935..19939
                     /gene="dppF"
                     /locus_tag="IRB70_003629"
     CDS             18935..19939
                     /gene="dppF"
                     /locus_tag="IRB70_003629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide ABC transporter ATP binding subunit
                     DppF"
                     /protein_id="HBC0633493.1"
                     /translation="MSTQEATSQQPLLQAIDLKKHYPVKKGMFAPERLVKALDGVSFN
                     LERGKTLAVVGESGCGKSTLGRLLTMIETPTGGELYYQGQDLLKHDPQAQKLRRQKIQ
                     IVFQNPYGSLNPRKKVGQILEEPLLINTSLSKDQRREKALSMMAKVGLKTEHYDRYPH
                     MFSGGQRQRIAIARGLMLDPDVVIADEPVSALDVSVRAQVLNLMMDLQQELGLSYVFI
                     SHDLSVVEHIADEVMVMYLGRCVEKGTKDQIFNNPRHPYTQALLSATPRLNPDDRRER
                     IKLTGELPSPLNPPPGCAFNARCRRRFGPCTQLQPQLKDYGGQLVACFAVDQDENPQR
                     "
     gene            complement(19969..21240)
                     /locus_tag="IRB70_003630"
     CDS             complement(19969..21240)
                     /locus_tag="IRB70_003630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HBC0633494.1"
                     /translation="MQHNTLPKHDQKMPFTRYDFGWVLLCIGMAIGAGTVLMPVQIGL
                     KGIWVFITAAIIAYPATWVVQDIYLKTLSESDSCNDYTDIISHYLGKNWGIFLGVIYF
                     LMIIHGIFIYSLSVVFDSASYLKTFGLTDADLSQSLLYKVAIFAVLVAIASGGERLLF
                     KISGPMVVVKVGIIVVFGFAMIPHWNFANITAFPQASVFFRDVLLTIPFCFFSAVFIQ
                     VLNPMNIAYRKREADKVLATRLALRTHRISYVTLIAVILFFAFSFTFSISHEEAVSAF
                     EQNISALALAAQVIPGHIIHITSTVLNIFAVLTAFFGIYLGFHEAIKGIILNLLSRII
                     DTRKINSRVLTLAICAFIVITLTIWVSFRVSVLVFFQLGSPLYGIVSCLIPFFLIYKV
                     AQLEKLRGFKAWLILLYGILLCLSPLLKLIE"
BASE COUNT         5225 a         5279 c         5654 g         5381 t
ORIGIN      
        1 tggggtcagt acaaagtgag gcccctctat gcatagacac cataaggtta gcctcttact
       61 cgttggaaat caacacagga ggctgggaat gccgcagaaa tatagattac tttctttaat
      121 agtgatttgt ttcacgcttt tatttttcac ctggatgata agagattcac tgtgtgaatt
      181 gcatattaaa caggagaatt atgagctggc ggcgttttta gcctgcaaat tgaaagagta
      241 agcgtcttcg gcgggaagtt attcccgcct ttcttacggc gttgcgcatt ctcattgcac
      301 ccaaatttat tcttcacaaa aataataata gattttatta cgcgaacgat tatttatttc
      361 ctgaataaac aaataaaaaa atccccgcca tttggcaggg atcttagatt ctgtgctttt
      421 aagcagagat tacaggctgg ttacgttacc agctgccggg cctttagcgc cgctttcgat
      481 ggtgaaggac actttctgac cttcgtccag agatttgtaa ccatcgttct ggatagcaga
      541 gaagtgtacg aacacgtctt tagagccatc gtcaggagtg atgaagccga agcctttgtc
      601 agcgttgaac cattttacga taccagtcat tttaccagac atagtgtatt acctttaata
      661 attaagtgtg cctttcggcg atatggcgtg ctttacagat tttgaagcgt taaaggaatg
      721 tgcactacga ggggtatcaa cgataactct tgaagggact tgccttacta cactgcttta
      781 atggtctgta cgtcaaaccg ttgatgtgca ttaagccacg cattggcggg tgatgcaaca
      841 attatttttc atatttatga ttaatcggtt ggaaaacggt cctgtcatca ggaccgtaaa
      901 cagcaataaa gtggataaaa gtctattcca tcaactgctt acttaatgcc gggttggctt
      961 gaatcaaacg catcaatttt agttcggcac ttgaaggctt cacgcgtctg gattcccatt
     1021 cctttaccat ggcgactgat acgcccaaaa cccgggcgaa atcatcgatt tttaaccctg
     1081 tcccttttcg taactgctca atttcggtac aggacgttgt tctgtgcgtc agggtaattt
     1141 tctgcgtttc atctttaaaa acaatctgtt ccaggctgct caacagctca tgcattggat
     1201 ctttatattc cattgaaaac tcctcaaatc acactgcggg atcgtgaatt gcatcgaagc
     1261 tcattaagaa tagtcgggaa aaacagacac agcggggtgt agtcagggca tgctctggct
     1321 atgattcgat tcagccagtc atttagcgtg acttatagcc acctaacgat ctgataaatg
     1381 ccgatatatc tcttaccact cccggtttgt aaagatttcg aaaatctaac gttctgagaa
     1441 ggcgtaaatc tctggctaca aaaaaagcaa cggcactatc attttttaac aatgaaacaa
     1501 caaattaacc ttgtttcatt ttctccatga ttttaccagg aagattacgt agaaagggta
     1561 tcctgcaagc ctgtcctgga ctatccttgt cacgtcagac acgcgtgtgt cgttgtgcgc
     1621 tttttttggg tgaaaggagt aagaaaatgg cgacaggaaa gtcctgctct cgctggtttg
     1681 cgcctcttgc ggcgttatta atggtagtta gcctgagtgg gtgttttgat aaagaaggcg
     1741 atcagcgtaa agcgtttatc gacttcctgc agaatacagt gatgcgtagc ggtgaacgtc
     1801 taccaaccct gactgccgat cagaaaaaac agtttggtcc ttttgtctct gattacgcga
     1861 ttctgtatgg ttattcacag caggtgaatc aggcgatgga ttccggtctg cgcccggttg
     1921 tagacagcgt taacgcaatt cgcgtaccgc aggattacgt tacgcaaagc ggcccactgc
     1981 gtgaaatgaa cggttcgctg ggtgtgctgg cgcaacagct gcaaaatgcg aagttgcagg
     2041 ccgatgctgc acactctgcg ttaaaacaga gtgatgacct gaaaccggtc tttgatcagg
     2101 cattcaccaa agtggtaacg acgccagctg atgcattgca accgttgatt ccggctgcac
     2161 aaactttcac gcaacaactg gtgatggttg gagactacat tgctcagcaa ggtactcagg
     2221 tgagctttgt cgcaaatggc atccagttcc cgacgtcaca gcaggcaagt gaatataaca
     2281 aactgattgc gccattaccg gcacagcatc aggcgtttaa tcaggcctgg actacagcag
     2341 ttactgcaac ccaataaaga gtaaaagccc gagcgattat cgggctttac tccacgcagt
     2401 cgcggcttag tccgcgacgt gcggattcac acagttcttc tcaacctttc cttgtaacgc
     2461 atcaatcaaa ttatccacgg cacaggcggc catgccataa cgcgtctcat gggtggcaga
     2521 tccaatatgc ggtactgcga cgacgttggc cattgagagc aacggcgaat ctacggacag
     2581 tggctcttgt tcgaagacat ccagcccggc ggcgtgaatt tcgcctttct gcaatgcagc
     2641 aatcagtgca ttttcatcaa ccaccgggcc acgtccggca ttaatgaaaa tggcggaggg
     2701 tttcattttg gcgaattgtt ctgcgccaaa cagatgatgc gtctcatccg ttaacggcag
     2761 gatcagacaa acgaaatctg actcttgtaa cagagtatcc aaatcgcagt agcgggcgtt
     2821 gaagcgttct tctgcttctt tatggtggcg acgcgcgtta tagaggatgg gcatgttgaa
     2881 gccaaagtgc gcacgttgtg ccagcgccat gccgatccgt cccatcccga caatgcccag
     2941 tgttttatgg tgaacgtcag tgccgtacca gtccgggcct atgctcgcgg tccattcgcc
     3001 tgcttttacc cgttctgcta cctccacaac ccgacgagcg gtagacaaca ccagcgccat
     3061 cagcgtatcg gcgacggttt ctgttaatac ggttggtgtg tgcatcagca gaatttttcg
     3121 ggcggtaagc gcatcgacat caaaattgtc atagccgacg gagatcgttg atgtggcacg
     3181 cagtttcggc attttttcca gcaatgcggc atcaacattc tcatttgaac ccagcaagcc
     3241 ttcagcttcg gcaaaaattg ctgcattttg ttcgacggtt tgtgggctga ggtttgctac
     3301 ctggtgaacg gtgaaatgtt cttgcaggcg ttgcagtaaa tcatcaggta aggctttgta
     3361 gaggataacg gacggcttca tgcttctctc cattcactga taaggcgatc accttagcct
     3421 gaaatatgat gaaggaaaac tgaagaatgc caggtgattt ctgcatcacc tgacatgaaa
     3481 gggattacag tgggcttaag gtaatttcta cacggcggtt ttgcgcctta ccttctgcgg
     3541 tgctgttgct ggcgattggg ttagccgggc caaggccctg agtacggatg cggctggcgt
     3601 ccacgccctg ggtgatcaac gcgctggcaa cggaatccgc acgctgctgg gagagacgca
     3661 tgttcaggtc gtgacccccc gtgctgtcgg tataaccaat cacgttaacc gccgttttcg
     3721 gatactcttt cagtaccatt gccacgccgg tcagggtgtt agcgcccgcc ggtttcaggg
     3781 ttgcgctgct gctgtcgaag gtcacattgt tcggcatatt gaggataatg ttatccccgc
     3841 tgcgggttac gctaacacca gtgccgcgca ttttgtcacg cagcttcgct tcctgcacat
     3901 ccatgtaata accaacgccg ccgcccagag ctgcgcctgc tgctgcgcca atgagcgcgc
     3961 ctttaccgcg atctttcttc gaagaagaga gcgcaccaat acccgcgcca acgagagagc
     4021 ccagacctgc gccgatagca gatttacctg cttcgcgttc gccggtgtaa gggttagttg
     4081 tacagccaga taccgccaga gcgccactca ctacggcggc aataagataa acacgtttct
     4141 tcattgttaa tccttaataa cctttttatt ctttgccacg ggttccgtgg cgggagatta
     4201 tgccgcgtga gcatgaagat tattcctggg aatactcgga aatttgtaag taatatttaa
     4261 ctgctcaata catctaacct ttcaggagtc ttcggtttgg ccaactcatc ctcacgatat
     4321 tccgttctga ctgccgccca ctgggggcct atgctggttg aaaccgacgg cgaaaccgtg
     4381 tttagctcgc gtggcgcgtt agccacagga atggaaaact ccttgcagag cgcggttcgc
     4441 gaccaggttc acagcaatac gcgggtgcga tttccaatgg tgcgcaaagg ctttcttgcg
     4501 tcaccggaaa atccgcaagg cattcgtggg caggatgaat ttgttcgcgt gagttgggat
     4561 gaggcgctgg agcttattca ccatcaacat aaacgtattc gtgaggctta tggtccggca
     4621 tcgatttttg ctggttccta cggctggcgt tcaaacggcg tgctgcataa ggcctcgaca
     4681 ttattacaac gctatatggc gcttgcaggc ggttataccg ggcatctggg ggattattcg
     4741 accggtgcag cacaggcgat catgccgtat gtcgtggggg gcagcgaagt ttatcaacag
     4801 caaaccagtt ggccgttggt attggaacat agcgatgtcg tggtgctatg gagtgctaac
     4861 ccactcaata cgctgaaaat tgcgtggaat gcatccgatg agcaggggct ttcttacttt
     4921 tccgcactgc gtgacagcgg gaaaaagctg atctgcattg atccaatgcg atcggaaacc
     4981 gtcgatttct ttggcgataa aatggaatgg gtggctccgc acatgggcac cgatgttgcg
     5041 ttgatgctgg ggatcgccca tacgctggtg gaaaatggtt ggcacgacga agcgtttctg
     5101 gcgcgttgca ccacaggtta tgccgtcttc gcctcttatt tgctgggcga gagtgacggt
     5161 atagcgaaaa acgccgaatg ggcggcagag atttgtggtg ttggcgcagc gaaaatccgc
     5221 gagctggcgg ctattttcca ccaaaatacc accatgctga tggcaggctg gggaatgcag
     5281 cgccaacagt ttggtgagca aaaacactgg atgctcgtca cgctggcggc aatgttgggg
     5341 caaatcggca cacccggcgg cggttttggt ctttcttacc attttgccaa tggtggtaac
     5401 cccacgcgcc gcgctgcggt gctctcttcc atgcagggca gcttgccggg tggcaccgat
     5461 gcggtagata aaatccctgt cgcccgcatt gttgaagcac tggaaaaccc tggtggcgca
     5521 tatcaacata acggtatgga ccgacatttc ccggatattc gttttatctg gtgggcgggc
     5581 ggtgccaact ttactcatca tcaggatacc aatcgcctga tccgtgcctg gcaaaaaccg
     5641 gagctggtgg tgatctctga atgcttctgg acggctgcgg cgaaacacgc ggatatcgtt
     5701 ctgcctgcga ccacttcgtt tgagcgtaat gatctcacca tgaccggcga ttacagtaat
     5761 cagcatctgg tgccgatgaa gcaagtggtg cctccacgtt atgaagcgcg taatgatttt
     5821 gatgtctttg ccgagttgag tgaacgttgg gagaagggcg gctatgcgcg gtttacggaa
     5881 ggaaaaagtg agctgcaatg gctggaaacg ttttataacg ttgcccggca gcgcggggca
     5941 agccagcagg ttgaattgcc gccatttgct gagttatggg aagccaacca gttaattgag
     6001 atgccggaaa acccggacag cgagcggttt attcgcttcg ccgattttcg ccgcgatccg
     6061 caggcgcatc cattaaaaac cgccagcggc aagattgaaa tcttctcgca gcgtattgct
     6121 gattacgctt atccggattg cccggggcat ccaatgtggc tggagccgga cgaatggcag
     6181 ggcaatgccg aaccggaaca gttgcaggta ctttctgctc atccggcaca tcgtctgcac
     6241 agccagctga attacagttc tctgcgcgaa ttgtacgcgg tggcaaaccg tgagcctgtc
     6301 accattcatc ctgacgatgc tcaggcgcgc ggcatacaag atggcgatac tgttcggctg
     6361 tggaacgcac gcgggcaaat tcttgccgga gcggtcatta gcgagggaat taaacctggc
     6421 gtgatttgca ttcatgaagg ggcatggccg gatctggatt taaccgctga cggtatttgt
     6481 aaaaacggcg cggtgaacgt tctgaccaaa gatctcccca gctcgcggct ggggaatggc
     6541 tgtgcgggta atacggcgct ggcatggctg gaaaaataca acggtccgga actgacactt
     6601 acagcgtttg aaccaccggc cagctcataa tccaggtggg tagttgggtt tcatcctgcc
     6661 atgcgcaatc gacaatgtga aaaccctgcg cctggtaaaa atctatcgcc ggttgatttt
     6721 tttgataaac ctccagcatc agatggggat ggcgctgctg cacatactgc attagcgcct
     6781 taccaatacc gcgtctgacg gccttcggtg cgacaaacat tgcagccaga aatcggcctt
     6841 ccataatgct gacaaaaccg agaagcttac cgtcttcttc ccagacccag ttttgcgcgt
     6901 tggcaagata ggcatcccgc accagcggaa tgcaatcacg ccagtaattc gcttttataa
     6961 agggatgccc ccaggttgta ctttccagcc acagttcgag gatcgcgggg agttctgaac
     7021 gttgcgcttc ccgaatcatg gtttatttcc cggatagcaa cagcagccaa ccacatgatc
     7081 attcaccagc ccacatgcct gcataaagga gtaacagatt gtggtaccaa caaacttaaa
     7141 accacgcttt ttcagggctt tagatagagc gtcggaggcg ggcgtagatg tagggatttc
     7201 gctcaacgtt gtggcttgtg tcacctgtgg ttgatgattg acaaacgacc agacaaagtc
     7261 ggcaaacggt tcgccgttct gttccatttg caggtacgcc cgcgcattac caataattgc
     7321 ctgaattttc ccgcgatggc ggataatccc ggcgtcctgt accagtcttt cgacatcctc
     7381 ttcctgcatt gctgccacct tcaccggatc gaactgatga aagctggcgc gatagttttc
     7441 gcgttttttg aggacggtga tccacgataa tccagcctgc tgcccttcaa ggcagatcat
     7501 ttcgaacagt tttttactgt cagtttcagg cacgccccat tcattatcat ggtaggcaat
     7561 ataaagcggg tcctgactca cccagccgca acgttccata ctttccctcg ctatgtaccc
     7621 gatcgtaaaa atttcagccg cttttcttga cgcatcggtg aaaaagtcaa tatttaatac
     7681 agggctacta tgcccgatat ccttcataca atgacaataa tattgccgaa ttcggctctt
     7741 ccctggagtc gtgttaatga tcataaaaaa aagcggtggt cgctggcagc taagcctgct
     7801 ggtgagcgtg gtaatcagtg ccttttttct caacacagct tacgcctggc aacaagaata
     7861 tatcgttgat acgcaacccg gacattccac agagcgttac acctgggata gcgatcatca
     7921 acctgattac aacgatattt tgtcgcaacg tattcaaagt agccaaaggg cgctgggact
     7981 ggaagtcaat ctggcggaag aaacccctgt ggatgtcacc agtagtatga gtatggggtg
     8041 gaattttcct ttatatcaac aggttacaac cggtccggtc gcggcattac attacgatgg
     8101 cacaaccacc tcgatgtata acgagtttgg cgacagtact accacgctga ctgatccgtt
     8161 atggcatgcc agcgtgagta ctttaggctg gcgtgttgac tcccggcttg gcgatctccg
     8221 accctgggcg caaatcagct ataaccagca atttggcgag aatatctgga aggcgcaatc
     8281 aggcctgagc cggatgacgg cgacaaacca gaacggcaac tggctggatg tcaccgtagg
     8341 cgctgatatg ttgctcaatc aaaatattgc tgcctatgcg gcgctatctc aggcagaaaa
     8401 taccactaac aatagcgact atctgtatac gatgggggtt agtgccagat tttaacgtta
     8461 tagatacaat tgaaacccat aaataacaac taatgtggcg atagtgggga ctaacttact
     8521 aaataataaa tttggcgaat aattgtcgag tcattcattc ctgaactaat gcatttcatt
     8581 ccgttctgat ggcatttcat gccgtttttc cccaggcata aagcgcactt cgttatggtt
     8641 gtcagcagag atttttcctt tttattactg caggaatact gccatgacac cttcaaatta
     8701 tcagcgtact cgctggctga cactcatcgg tactatcatt acccagtttg ctctggggtc
     8761 ggtttatacc tggagtctgt ttaacggtgc gctttctgcc aagctggggg ctcctgtaag
     8821 ccaggttgct ttctctttcg gcttgttaag tctggggctg gcaatttcat cttctgttgc
     8881 gggcaaattg caggaacgtt ttggcgttaa acgcgtcacc atggcttccg gcattttgct
     8941 gggattaggc ttcttcctga ccgcgcattc caacaacctg atgatgctgt ggttaagcgc
     9001 cggtgtgctg gtcggtctgg cggatggcgc gggttacctg ctgacgctct ctaactgcgt
     9061 gaagtggttt ccggagcgta agggacttat ctctgctttt gctatcggtt cttatggtct
     9121 gggcagcctg ggttttaaat ttatcgacac gcacctgctc gaaacggtgg gtctggaaaa
     9181 aacctttgtt atttggggcg cgattgtact ggtgatgatt gtctttggcg caacgttaat
     9241 gaaagatgcg ccgaagcagg aagtgaaaac cagcaatggt gtggtggaga aggactacac
     9301 cctggcagag tcgatgcgta aaccgcagta ctggatgtta gcggttatgt tcctgactgc
     9361 gtgcatgagt ggtctgtatg tgattggtgt agcgaaagat atcgctcaaa gtctggcgca
     9421 tcttgatgca atttccgcag ccaatgctgt gacggttatt tccatcgcca acctttctgg
     9481 tcgtctggtg ctgggtattc tgtctgacaa aatcgcccgt atccgtgtta tcaccattgg
     9541 tcaggtgata tcgctggtgg gtatggcggc cctgctgttt gcaccattga atgcagtgac
     9601 gttctttgca gcgattgcct gcgtggcgtt taactttggc ggcactatca cggtgttccc
     9661 gtcactggtc agtgagttct tcggcctcaa taacctggcg aaaaactacg gtgtgattta
     9721 tctcggtttc ggtatcggca gcatttgtgg gtcgattatc gcctcactgt ttggcggctt
     9781 ctatgtgact ttctacgtca tttttgccct gctgattctg tcactggcgc tctctacgac
     9841 gattcgtcag ccagagcaga aaatgttgcg tgaggcgcat ggctcccttt aatcatctgc
     9901 cgcgagctac tgggctttag ccttagtgtg aatcaaacgc ttcaacgcaa tgtataaaca
     9961 atgacgcgta aaatttgggc cagttaactg gcccttttta ctgctttttg taacgctaaa
    10021 gtctcttttc aaacttgcat ttttgtaaat ttgtgcttca tgcacactct ttccccacac
    10081 tttttccctt tgctgtggtc tacttattcg cgcgtgtaga ttttacttat ctgactacct
    10141 ccgcactttt cccctgccgg gcctgaaaag ccgctaagca gggtgttatc acctgtttgt
    10201 ccagggtttg tttgcatgag atacatcaaa tcgattacac agcagaagct gagctttttg
    10261 cttgcaatct atattggcct ttttatgaat ggcgcggttt tttaccgccg tttcggcagc
    10321 tatgcgcacg attttaccgt ctggaaaggc atttctgctg ttgttgaact ggctgccacc
    10381 gtactggtga ccttcttttt actacgtctt ctttcgctgt ttggccgccg cagctggcgt
    10441 attctggcat cgctggtggt gctcttttcc gcaggtgcca gctattacat gaccttcctt
    10501 aatgtagtca ttggttatgg catcatcgca tccgtcatga ccaccgatat cgacctgtca
    10561 aaagaagttg ttggtctgaa ctttattctc tggttaatcg ccgtaagcgc gttgcctctt
    10621 atccttatct ggaataaccg ctgtcgttac accttgctcc gacaactgcg aaccccaggg
    10681 cagcgtattc gcagcctggc ggtcgtcgta ctggcaggta ttatggtttg ggcaccgatt
    10741 cgtttgctgg atatccagca gaagaaagtg gagagggcga caggtgttga tttgccgagt
    10801 tatggcggcg tcgtcgcgaa ctcttatctg ccatcaaact ggctttcggc attaggtctt
    10861 tatgcctggg cgcgggtcga tgaatcttcc gataacaatt ctctccttaa ccctgcgaag
    10921 aagtttacgt accaggctcc acaaaacgtt gatgatacat atgtcgtttt cattattggt
    10981 gaaaccacgc gctgggatca tatgggcatt ttcggctatg aacgcaatac cacaccgaaa
    11041 ctggctcagg agaaaaatct ggcggcgttc cgtggttact cctgtgatac tgcaaccaaa
    11101 ctctcactgc gttgcatgtt tgtacgtcag ggtggagcag aagataatcc gcagcgcaca
    11161 ttaaaagaac agaatatttt cgcggtgctg aagcagttag gattcacttc tgatctctac
    11221 gctatgcaaa gcgaaatgtg gttctacagc aatacgatgg cggacaacat tgcttatcgt
    11281 gagcagattg gtgcggagcc acgtaaccgt ggcaaaccgg tagatgatat gttgctggta
    11341 gacgaaatgc agcagtcgct ggggcgcaac ccggatggta agcatctgat cattctgcat
    11401 accaaaggct cacactttaa ctacacccag cgttacccgc gcagctttgc gcagtggaag
    11461 ccggaatgta ttggtgttga tagcggctgt accaaagcgc agatgatcaa ctcatacgac
    11521 aactcggtga cctatgtgga tcactttatt tccagcgtga ttgatcaggt tcgcgataag
    11581 aaagcgattg tgttctatgc agctgaccac ggtgagtcaa ttaatgaacg cgagcacctg
    11641 cacggcacgc cgcgtgaact ggcaccgccg gaacagttcc gtgtgccgat gatggtctgg
    11701 atgtcggata aatatctgga aaatccggtc aatgcgcagg catttgcgca gctgaaaaaa
    11761 gaagccgaca tgaaagtgcc acgccgtcat gtagagctgt acgacaccat catggggtgt
    11821 cttggctata cttcaccgga tggtggaatt aacgaaaaca acaactggtg ccacatcccg
    11881 caggcaaaag aggcagcggc taactaagaa gcctgctgac tttctcgccg atcaaaaggc
    11941 attttgctat taagggattg acgagggcgt atctgcgcag taagatgcgc cccgcattcg
    12001 gtgattggcg cagcctggta gcgcacttcg ttcgggacga aggggtcgga ggttcgaatc
    12061 ctctatcacc gaccaaattc gaaaagcctg ctcaacgagc aggctttttt gcatctgtag
    12121 ctcatgagga agagaacccc cgggggcggg gaggttcgat tcgacgtagg cctgataaga
    12181 cgcgccatga actgcacccc aaatgttgga cataatctga catctgaagg tgcagtttat
    12241 gaaacatcca tttgaagtaa aacttgccgc cgtaaatcat tacctggccg gtcatgctgg
    12301 catcatttct acggcaaaac tatttcaact ttctcacacc agcctctcac actggattaa
    12361 tctttttctt cttcacggtc ctctggcact ggattgcaga cacaggcgta gctattctcc
    12421 tgaagataaa ctttgcgtgg ttctttatgc tctcgggcat tctgagtctc taccccgggt
    12481 agctgcccgg tttaacattc ccagccacaa cacggttaaa aactggataa aaggctacca
    12541 caaatctggt gatgaggcct ttatcaggcg caggaaggag aaaagcatga cccgttctga
    12601 tgatacccat gaaaacgagg caaacatgac gccggaagag atgaagaatg agctgcgtta
    12661 tcttcgcgca gaaaatgcat atctgaaagc catgcaggag catctcctgg aaaaaaagcg
    12721 cctggagctg gagaaaaagc gaaagtcatc cagaacctga ggtgcggaca ctgccagtct
    12781 gacctgttaa aggccgcagg gctggccaga agcacgctgt actatcagct gtcactgcag
    12841 aaggctaagg acaagtatgc tgatgtgaaa cagctcatag cctccatctt ccatgaacac
    12901 cggggatgtt atgggtaccg gcggatccac tgtgaacttc agaaaagagg tctcaagttc
    12961 agtggcaaaa cggtgcgaaa actgatgcag cagcttggcc tgaagtctcc tgtgcgcctg
    13021 aagaaatacc ggtcttatcg ggggaacatg ggactcgctg cagaaaatat ccttcagcga
    13081 cagttcaaag cgaaagctcc ctgtgagaaa tgggtgacag atatcaccga attcagggct
    13141 ggcggacaaa aactgtacct gtccccgata cttgatttgt ttaacgggga aatcgtggca
    13201 tgggaaacag cctgcaggcc tacagaggag ctggtgaagc ggatgttaaa taaggggctg
    13261 gaaagccttg ctgaagggga gaaaccgctg ctccatagtg atcaaggatg gcattaccgg
    13321 ataaaaagtt atcagtccgc cctggcagac agagggttag tgcagagcat gtcacgcaag
    13381 ggcaactgcc ttgataatgc ggtaatggag aacttctttg gtcacctgaa agaagaaatg
    13441 tactatcgcc gggactacag gagtgtagaa gaactggaaa atgccgttag cgaatacata
    13501 acttactgga atcaaaaaag aataaaactc agtcttgggg gactcagccc ggtggaatac
    13561 cggactgagt atcaaaaaac cggttaactg aaactgtcca ggttttgggg ttcagttcag
    13621 ccagcgtcgc atcaggcaaa tgtaccggcc cattgtcgga tgcggcgcga ccgccttatc
    13681 cgatctacac accacacatt tccctgccaa atttgcgccc catatctcac tatccattaa
    13741 cggatttgtg acagaaacca ttgtcttttt ttatatttgc ttaaatcttt ttttgcgtta
    13801 cttatggctg gcgctggcat tttcccctgt gcgttttagc gttcatggta ttaatcgctc
    13861 agatatccac ctttacctca gatttttttc attaaatgca taaaacttaa tcaccaaatg
    13921 ttgctaaata ttaagctgat tgttctggtt gtgttggcgt agcacaaatt tctctgctgc
    13981 aaatagctgt ttgaagtttt tttaatcttt gtttgttgat tctcaccgtt ggtgtaaatc
    14041 ccggttggct gtattgacgt tttcacattc tgttgacaga ttgtaggtca cgaggggcat
    14101 tttctggagg atccgcactg ttacactgat gttaattagt acggcatccc cacctcataa
    14161 cgttgacccg accgggcaaa aaacaaaaaa ggtcaggcgg cgacaaccca ctgcaaaggg
    14221 ttaaaacaac aaacatcaca attggagcag aataatgcgt atttccttga aaaagtcagg
    14281 gatgctgaag cttggtctca gcctggtggc tatgaccgtc gcagcaagtg ttcaggctaa
    14341 aactctggtt tattgctcag aaggatctcc ggaagggttt aacccgcagc tgtttacctc
    14401 cggcaccacc tatgacgcct cttccgtacc gctttataac cgtctggttg aatttaaaat
    14461 cggcaccacc gaagtgatcc cgggcctcgc tgaaaagtgg gaagtcagcg aagacggtaa
    14521 aacctatacc ttccatctgc gtaaaggtgt gaagtggcac gacaataaag aattcaaacc
    14581 gacgcgcgaa ctgaacgccg atgacgtggt gttctcgttc gatcgtcaga aaaacgcgca
    14641 aaacccgtac cataaagttt ctggcggcag ctacgaatac tttgaaggca tgggcttgcc
    14701 ggagctgatc agcgaagtga aaaaggtgga cgataacacc gttcagtttg tgctgactcg
    14761 ctcggaagcg ccgttcctcg ctgacctggc aatggacttc gcctctattc tgtcaaaaga
    14821 atatgctgac gcgatgatga aagccggtac accggaaaaa ctggatctca acccaatcgg
    14881 taccggcccg ttccagttac agcagtacca gaaagattcc cgtattcgct ataaagcgtt
    14941 tgatggctac tggggcacca aaccgaagat cgatacgctg gtcttctcta ttactcctga
    15001 cgcttccgtg cgttacgcga aattgcagaa gaacgaatgc caggtgatgc cgtacccgaa
    15061 cccggcagat atcgcccgca tgaagcagga taaatccatc aacctgatgg aaatgccggg
    15121 gctgaatgtc ggttatctct cgtataacgt gcagaaaaaa ccactggatg acgtgaaagt
    15181 tcgccaggct ctgacctacg cggtgaacaa agacgccatc atcaaagcag tttatcaggg
    15241 cgcgggcgta tcagcgaaaa acctgatccc gccaaccatg tggggctata acgacgacgt
    15301 tcaggactac acttacgatc ctgaaaaagc gaaagccttg ctgaaagaag cgggtctgga
    15361 aaaaggtttc tccatcgacc tgtgggcaat gccagtacaa cgtccgtata acccgaatgc
    15421 tcgccgcatg gcggagatga ttcaggcaga ctgggcgaaa gtgggcgtgc aggccaaaat
    15481 cgtcacctac gaatggggtg agtacctcaa gcgtgcgaaa gatggcgagc atcagacggt
    15541 aatgatgggc tggactggcg ataacgggga tccggataac ttcttcgcca ccctgttcag
    15601 ctgcgccgcc tctgaacaag gctccaacta ctcaaaatgg tgctacaaac cgtttgaaga
    15661 tctgattcaa ccggcgcgtg ctaccgacga ccacaataaa cgtgttgaac tgtacaaaca
    15721 agcacaggtc gtgatgcacg atcaggctcc ggcactgatc atcgctcact ccaccgtgtt
    15781 tgaaccggta cgcaaagaag ttaaaggcta tgtggttgat ccattaggca aacatcactt
    15841 cgaaaatgtc tctatcgaat aattaaaagc catacccggt ggcgctgtgc ctctgcgtgc
    15901 agcgccatcc ggcagcaata cttcattccc tgtcccacaa aggcgggaat tgatttgtga
    15961 gcaatacaga cacgcagttc caggctgcgg gtcattatag agaatccggg ttatgttgca
    16021 gtttattctc cgacgtttgg gactcgtcat ccccacgttt atcggtatta cccttctcac
    16081 atttgccttt gtccacatga tcccgggcga tccggtgatg atcatggcgg gcgagcgtgg
    16141 gatctcccca gagcgtcacg cgcaattgct ggctgaactc ggcttagata aaccgatgtg
    16201 gcagcagtat ctccattaca tttggggcgt aatgcacggt gatttaggca tttccatgaa
    16261 aagccgaatt ccggtatggg aagagttcgt gccgcgcttt caggctacgc tggaacttgg
    16321 cgtctgcgcg atgatttttg cgacggcagt cggtattccg gttggtgtgc tggctgcggt
    16381 taaacgtggt tccattttcg atcacacagc ggttggcctg gcgctgaccg gctactcgat
    16441 gccaattttc tggtggggca tgatgctgat catgctggtt tcggtgcact ggaacctgac
    16501 gcctgtctcc ggtcgtgtga gcgacatggt gttcctcgat gattccaatc cgttaaccgg
    16561 ttttatgctg atcgacaccg ccatctgggg tgaagacggt aactttatcg atgccgtcgc
    16621 ccatatgatc ctacccgcca ttgtgctggg taccatcccg ctggcggtca ttgtgcgtat
    16681 gacgcgctcc tcgatgctgg aagtgctggg cgaagattat atccgcaccg cgcgtgccaa
    16741 aggtcttacc cggatgcggg tgattatcgt ccatgcgctg cgtaacgcga tgctgccggt
    16801 ggtgaccgtt atcggcctgc aggtgggaac attgctggcg ggggcgattc tgactgaaac
    16861 catcttctcg tggcccggtc tggggcgctg gttgattgac gcactgcaac gccgcgatta
    16921 tccggtagtg cagggcggcg tattgctggt ggcgacgatg attatcctcg tcaacctgct
    16981 ggtcgatttg ctgtacggcg tggtgaaccc gcgtattcgt cataagaagt aaggggacat
    17041 catgtcacag gttactgaaa ataaagtgat tagcgcaccg gtgccgatga ccccgttaca
    17101 ggagttctgg cactatttta aacgcaacaa aggcgcggtt gtcgggctgg tttacgtcgt
    17161 catcgtgctg tttatcgcga tctttgccaa ctggattgca ccctataacc cggcggaaca
    17221 gttccgcgat gcactgctcg ccccgccagc ctggcaggaa ggcggcagca tggcgcactt
    17281 gctgggcact gatgacgtgg ggcgtgatgt gctgtcgcgg ctgatgtacg gcgcgcgctt
    17341 gtcgctgctg gttggctgtc tggtagtggt gttatcgctg attatgggcg ttattctcgg
    17401 cctgatcgct ggttactttg gcggtctggt cgataacatc atcatgcgcg tggtcgatat
    17461 catgctggcg ctgccaagtc tactgctggc actggtgctg gtggcgattt tcggcccgtc
    17521 gattggtaac gccgcgctgg cgctaacctt cgttgcgctg ccgcattatg tgcgcttaac
    17581 ccgcgccgcc gtgctggtgg aagttaaccg cgattacgtc accgcgtctc gcgtggcggg
    17641 tgccggggca atgcgccaga tgtttattaa catcttcccg aactgccttg cgccgctgat
    17701 tgttcaggcg tcgctcggtt tctctaacgc cattctcgat atggctgctc ttggtttcct
    17761 cggcatgggg gctcagccgc caacaccgga gtggggcact atgctctccg acgtgttgca
    17821 gtttgcgcaa agcgcctggt gggtcgtgac cttcccgggt ctggcgatac tgctgacggt
    17881 gctggcattt aacctgatgg gtgacggtct gcgtgacgcg ctcgatccca aactgaagca
    17941 gtaagaggtt cgagatggcg ttattaaatg tagataaatt atcggtgcat ttcggcgacg
    18001 aaagcgcacc gttccgcgcc gtagaccgca tcagctacag cgtaaaacag ggcgaagtgg
    18061 tcgggattgt gggtgagtcc ggctctggta aatcggtcag ttcgctggcg attatggggc
    18121 tgattgatta tccgggccgc gtaatggcgg aaaagctgga gtttaacggt caggatttac
    18181 agcgtatctc agaaaaagag cgccgcaacc tggtgggtgc cgaagtggcg atgatcttcc
    18241 aggacccgat gaccagcctt aacccgtgct acaccgtggg tttccagatt atggaagcga
    18301 ttaaggtgca tcagggcggc aacaaaagta cccgccgtca gcgggcgatt gacctgctga
    18361 atcaggtcgg tattcccgat ccggcatcgc gtctggatgt ttacccgcat cagctttccg
    18421 gcggcatgag ccagcgcgtg atgatcgcca tagcgattgc ctgtcggcca aaactgctga
    18481 ttgccgatga accgaccacc gcgctggacg tgaccattca ggcgcaaatc atcgaactgc
    18541 tgctggagct acagcagaaa gagaacatgg cgctggtgtt aattacccat gacctggcgc
    18601 tggtggcgga agcggcacat aaaattatcg tgatgtatgc aggccaggta gtagaaacgg
    18661 gcgatgcgca cgccatcttc catgcgccgc gtcacccgta tactcaggca ttgctgcgtg
    18721 cgctgccgga atttgctcag gataaagaac gtctggcgtc gttgccaggt gttgttcccg
    18781 gcaagtatga ccgtccgaac ggctgcctgc ttaacccgcg ctgcccctac gccactgaca
    18841 aatgccgcgc tgaagaaccg gcgctgaata tgctcgctga cgggcgtcag tccaaatgcc
    18901 actacccact tgatgatgcc gggaggccga cactatgagt acgcaagagg ccacctcgca
    18961 acaaccgctg ttgcaggcta tcgacctgaa aaaacattat ccggtgaaga aaggtatgtt
    19021 cgcgccggaa cgtctggtga aggcgctgga cggcgtttcg tttaaccttg aacgtggcaa
    19081 aacgctggca gtagtaggtg aatctggctg cggtaaatcg accctcggtc ggttactgac
    19141 gatgatcgaa acgcccaccg gtggtgagct gtattaccag gggcaggatc tgctcaagca
    19201 cgatccgcag gcgcagaagt tgcgtcggca gaaaatccag atcgtctttc agaatcccta
    19261 tggttcgcta aatccgcgta aaaaagttgg gcaaattctt gaagagccgc tgcttattaa
    19321 taccagctta agcaaagatc agcgtcggga aaaagccctg tcgatgatgg cgaaagtcgg
    19381 cctgaaaacc gagcattacg accgctatcc gcatatgttc tccggcggtc agcgtcagcg
    19441 tatcgccatt gcccgtggtc tgatgctcga cccggatgtg gtgattgccg atgagccggt
    19501 ttccgcgctg gacgtctcag tgcgtgcgca ggtgctcaac ctgatgatgg atttgcagca
    19561 ggagttgggg ctgtcttatg tctttatctc ccacgacctg tcagtggttg agcacattgc
    19621 cgatgaagtg atggtgatgt acctgggccg ctgcgtggag aagggaacga aggaccaaat
    19681 cttcaataac ccgcgtcatc cgtacactca ggcgctactc tccgcgacgc cgcgcctgaa
    19741 cccggacgat cgccgcgagc gcatcaagct caccggtgaa ctgccaagcc cgctcaatcc
    19801 accgccgggc tgcgcgttta acgcccgctg tcgtcggcgc ttcggcccct gcacccagtt
    19861 gcagccgcag ctaaaagact acggcggtca actggtagct tgttttgctg ttgatcagga
    19921 tgaaaatccg cagcgttaac tcacaaaacc ggggccgtgc gctccggttt actcaatcag
    19981 cttcaacagt ggcgacaagc atagcaaaat gccgtaaagc agaatcagcc aggctttaaa
    20041 tccgcgaagt ttttccagtt gtgcgacttt atagatcagg aaaaacggaa tgaggcacga
    20101 cacaatgcca tataacgggc ttcccaactg aaagaacacc agcaccgata cacgaaacga
    20161 aacccaaatc gtcaacgtaa tgacgataaa agcgcagatc gccagagtca gcacgcgtga
    20221 attaattttc ctggtatcaa taattcggct taacagattg agaataatgc ctttaatggc
    20281 ctcgtggaaa ccgagataaa tgccaaagaa tgcggtcagt acggcaaaga tattcagcac
    20341 cgtagaggtg atatgaatga tatgcccagg gatcacctgc gcggccagtg ccagtgccga
    20401 gatattttgt tcaaaggcag aaacggcttc ttcgtggcta attgagaagg taaacgaaaa
    20461 ggcaaaaaac aggatcaccg cgatgagcgt gacataacta attcggtggg tacgcagcgc
    20521 gagccgggtt gccagtactt tatccgcttc ccgtttacga taggcaatat tcattgggtt
    20581 aagtacctga ataaataccg cagaaaagaa gcaaaaggga atggtaagca ggacatcgcg
    20641 gaaaaagacg gaggcttgcg ggaaggcggt tatattggcg aaattccagt gcgggatcat
    20701 cgcaaaaccg aacacgacga taatccctac tttgaccacc accattggcc cggaaatctt
    20761 aaacagtaat cgttcaccac cagacgcaat tgccaccagt acggcgaaaa tggcgacttt
    20821 ataaagtaga gattgtgaaa gatcggcatc ggttaaaccg aaggttttca ggtacgaggc
    20881 gctgtcgaaa accacggaga gagagtagat aaaaatcccg tggataatca tcaaaaagta
    20941 gataaccccg aggaaaattc cccagttctt ccccaggtaa tgactgataa tatcggtgta
    21001 gtcattacag gaatcgcttt cagaaagggt ttttaaataa atgtcctgca ctacccaggt
    21061 ggcaggataa gcaatgatcg ctgcggtaat aaatacccaa attcccttca agccaatttg
    21121 tactggcatc agcacggttc cggcaccaat cgccatgcct atgcataata aaacccagcc
    21181 gaagtcgtag cgtgtaaacg gcattttctg atcgtgtttc ggtagtgtgt tgtgctgcat
    21241 aaagtcctgt ccagaaagaa gtcggcctcg caaaaatgaa taaacccagt ttctcttgcg
    21301 caacaggtgg agaagtcgaa tacgcagtat gtaaaaaatg aggcaacaga ttcactgggg
    21361 aggtcgcgag gaggcgcaat tctacaaaaa tgcgcatttc actaccagtc tggagtcagc
    21421 ccggatatga actgcaacta ttgcaaataa agaaattaag ctggaatgca tcacgcaatg
    21481 aggaagattg ccgggtgctg acggtaaaaa gcaatcgtag aatcagcggc aagccggaa
//
LOCUS       DADXDL010000084        21423 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.084, whole genome shotgun sequence.
ACCESSION   DADXDL010000084 DADXDL010000000
VERSION     DADXDL010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21423
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.084"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..815)
                     /locus_tag="IRB70_003631"
     CDS             complement(<1..815)
                     /locus_tag="IRB70_003631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633495.1"
                     /translation="MSIDFTPGMINTYHGDIYNRTTDTDNAKTPDTPMWPCDNQEEQQ
                     PINFSLSEEGYNAEQFDLAQQQLQQINACHTNTTYTNADYSKVVAQLVKLINNIETIS
                     STPLTQQTQSILNQINNIRYEKNKNSESKIIVVFNPKPNKPIITKILVEEGIPVRFSV
                     QTVSSENKNFSGQRTDLPTDIKDIQRLYQKMTRLYIEHSENENRMKVFAGTNFIDFNM
                     TGQDLSGFVLTLSRFYFEDLLNVNFTDANLFDTIFSHKENPITNLHKDEQYVD"
     gene            complement(1395..2396)
                     /locus_tag="IRB70_003632"
     CDS             complement(1395..2396)
                     /locus_tag="IRB70_003632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000100290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBC0633496.1"
                     /translation="MSSWLAMLQDAAEMFVFLAVELSLLFIVISAGVSLIRQKVPDHK
                     IQQMMGARKGRGYLLAALLGAVTPFCSCSTIPMLRGLLSAKAGFGPTLTFLFVSPLLN
                     PIIVGLMWVTFGWKVTLLYAIIAAGVSVLASIILDSLGFERHIIASKSSSANCCAPAK
                     TSPGTTYTPIEVSCCSPTAKAIEKPVVNCCNTKAVVSINPIKLATKDALQQFKDVLPY
                     LLLGVLIGSFIYGFIPSEWIAAHAGADNPFAIPLSAVVGIPLYIRAEAVIPLASVLMT
                     KGMGLGALMALIIGSAGASLTEVILLKSMFRIPMIVAFLTVILGMAILMGYLTQMLF"
     gene            2503..2823
                     /locus_tag="IRB70_003633"
     CDS             2503..2823
                     /locus_tag="IRB70_003633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001614035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0633497.1"
                     /translation="MQLEEVAKALKELGHPTRLFIFKHLVKAGEQGLPVGELQKQLGI
                     PGSTLSHHISALVSVGLVKQNRESRTLMCVSQYAMLEAIIEFLREECCVNSKTDGEGA
                     TKNK"
     gene            complement(2844..3269)
                     /gene="arsC"
                     /locus_tag="IRB70_003634"
     CDS             complement(2844..3269)
                     /gene="arsC"
                     /locus_tag="IRB70_003634"
                     /EC_number="1.20.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-dependent arsenate reductase"
                     /protein_id="HBC0633498.1"
                     /translation="MSNITIYHNPACGTSRNTLEMIRNSGTEPTIVYYLETPPTRDEL
                     VKLIADMGISVRALLRKNVEPYEELGLAEDKFTDDRLIDFMLQHPILINRPIVVTPLG
                     TRLCRPSEVVLEILPDAQQRAFTKEDGEKVVDEAGKRLK"
     gene            complement(3282..4571)
                     /gene="arsB"
                     /locus_tag="IRB70_003635"
     CDS             complement(3282..4571)
                     /gene="arsB"
                     /locus_tag="IRB70_003635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenite/antimonite:H(+) antiporter ArsB"
                     /protein_id="HBC0633499.1"
                     /translation="MLLAGAIFVLTIVLVIWQPKGLGIGWSATLGAVLALVTGVVHPG
                     DIPVVWNIVWNATAAFIAVIIISLLLDESGFFEWAALHVSRWGNGRGRLLFTWIVLLG
                     ATVAALFANDGAALILTPIVIAMLLALGFNKGTTLAFVMAAGFIADTASLPLIVSNLV
                     NIVSADFFDLGFREYASVMVPVDIAAILATLVMLHLYFRKDIPQNYDMALLKSPAEAI
                     KDPATFKAGWVVLLLLLVGFFVLEPLGIPVSAIAAVGVLILFVVAKRGHAINTGKVLR
                     GAPWQIVIFSLGMYLVVYGLRNAGLTEYLSGVLNVLADNGLWAATLGTGFLTAFLSSI
                     MNNMPTVLVGALSIDGSTASGVIKEAMVYANVIGCDLGPKITPIGSLATLLWLHVLSQ
                     KNMTISWGYYFRTGIIMTLPVLFVTLAALALRLSFTL"
     gene            complement(4626..4979)
                     /gene="arsR"
                     /locus_tag="IRB70_003636"
     CDS             complement(4626..4979)
                     /gene="arsR"
                     /locus_tag="IRB70_003636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="As(III)-sensing metalloregulatory
                     transcriptional repressor ArsR"
                     /protein_id="HBC0633500.1"
                     /translation="MSFLLPIQLFKILADETRLGIVLLLSELGELCVCDLCTALDQSQ
                     PKISRHLALLRESGLLLDRKQGKWVHYRLSPHIPAWAAKIIEQAWRCEQEKVQVIVRN
                     LARQNCSADSKNICS"
     gene            5718..5801
                     /locus_tag="IRB70_003637"
     CDS             5718..5801
                     /locus_tag="IRB70_003637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165328.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Damage inducible protein"
                     /protein_id="HBC0633501.1"
                     /translation="MIDKAIIVLGALIALLELIRFLLQLLN"
     gene            complement(5855..7207)
                     /gene="gorA"
                     /locus_tag="IRB70_003638"
     CDS             complement(5855..7207)
                     /gene="gorA"
                     /locus_tag="IRB70_003638"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003861215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBC0633502.1"
                     /translation="MTKHYDYIAIGGGSGGIASINRAAMYGQKCALIEAKELGGTCVN
                     VGCVPKKVMWHAAQIREAIHMYGPDYGFDTTINKFNWETLIASRTAYIDRIHTSYENV
                     LGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVEYGIDSDGF
                     FALPALPERVAVVGAGYIAVELAGVINGLGAKTHLFVRKHAPLRSFDPMISETLVEVM
                     NAEGPQLHTNAIPKAVVKNADGSLTLELEDGRSETVDCLIWAIGREPANDNINLEAAG
                     VKTNEKGYIVVDKYQNTNVEGIYAVGDNTGAVELTPVAVAAGRRLSERLFNNKPDEHL
                     DYSNIPTVVFSHPPIGTVGLTEPQAREQYGDDQVKVYKSSFTAMYTAVTTHRQPCRMK
                     LVCVGPEEKIVGIHGIGFGMDEMLQGFAVALKMGATKKDFDNTVAIHPTAAEEFVTMR
                     "
     gene            complement(7279..8121)
                     /gene="rlmJ"
                     /locus_tag="IRB70_003639"
     CDS             complement(7279..8121)
                     /gene="rlmJ"
                     /locus_tag="IRB70_003639"
                     /EC_number="2.1.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2030)-N(6))-methyltransferase"
                     /protein_id="HBC0633503.1"
                     /translation="MLSYRHSFHAGNHADVLKHTVQSLIIESLKEKDKPFLYLDTHAG
                     AGRYQLGSEHAERTGEYLEGIARIWQQDDLPAELEAYINVVKHFNRSGQLRYYPGSPL
                     IARQLLREQDSLQLTELHPSDYPLLRSEFQKDNRARVEKADGFQQLKAKLPPVSRRGL
                     ILIDPPYEMKTDYQAVVSGIAEGYKRFATGTYALWYPVVLRQQIKRMIHDLEATGIRK
                     ILQIELAVLPDSDRRGMTASGMIVINPPWKLEQQMNNVLPWLHSKLVPAGTGHATVSW
                     IVPE"
     gene            8324..10366
                     /gene="prlC"
                     /locus_tag="IRB70_003640"
     CDS             8324..10366
                     /gene="prlC"
                     /locus_tag="IRB70_003640"
                     /EC_number="3.4.24.70"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptidase A"
                     /protein_id="HBC0633504.1"
                     /translation="MTNPLLTPFELPPFSKILPEHVVPAVTKALNDCRENVERVVAQG
                     APYTWENLCQPLAEVDDVLGRIFSPISHLNSVKNSPELREAYEQTLPLLSEYSTWVGQ
                     HEGLYKAYRDLRDGDHYATLNTAQKKAVDNALRDFELSGIGLPKEKQQRYGEIATRLS
                     ELGNQYSNNVLDATMGWTKLVTDEAELAGMPESALAAAKAQAEAKELEGYLLTLDIPS
                     YLPVMTYCDNQALREEMYRAYSTRASDQGPNAGKWDNSKVMEEILALRHELAQLLGFE
                     NYAFKSLATKMAENPQQVLDFLTDLAKRARPQGEKELAQLRAFAKAEFGVDELQPWDI
                     AYYSEKQKQHLYSISDEQLRPYFPENKAVNGLFEMVKRIYGITAKERKDVDVWHPDVR
                     FFELYDENNELRGSFYLDLYARENKRGGAWMDDCVGQMRKADGSLQKPVAYLTCNFNR
                     PVNGKPALFTHDEVITLFHEFGHGLHHMLTRIETAGVSGISGVPWDAVELPSQFMENW
                     CWEPEALAFISGHYETGEPLPKELLDKMLAAKNYQAALFILRQLEFGLFDFRLHAEFR
                     PDQGAKILETLAEIKKLVAVVPSPSWGRFPHAFSHIFAGGYAAGYYSYLWADVLAADA
                     FSRFEEEGIFNRETGQSFLDNILSRGGSEEPMDLFKRFRGREPQLDAMLEHYGIKG"
     gene            10374..11126
                     /gene="rsmJ"
                     /locus_tag="IRB70_003641"
     CDS             10374..11126
                     /gene="rsmJ"
                     /locus_tag="IRB70_003641"
                     /EC_number="2.1.1.242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(1516)-N(2))-methyltransferase
                     RsmJ"
                     /protein_id="HBC0633505.1"
                     /translation="MKICLIDETGTGDGALSVLAARWGLEHDEDNLMALVLTPEHLEL
                     RKRDEPKLGGIFVDFVGGAMAHRRKFGGGRGEAVAKAVGIKGDYLPDVVDATAGLGRD
                     AFVLASVGCRVRMLERNPVVAALLDDGLARGYADAEIGGWLQERLQLIHASSLTALTD
                     ITPRPQVVYLDPMFPHKQKSALVKKEMRVFQSLVGPDLDADGLLEPARLLATKRVVVK
                     RPDYAPPLANVATPNAVVTKGHRFDIYAGTPV"
     gene            complement(11175..12644)
                     /gene="dtpB"
                     /locus_tag="IRB70_003642"
     CDS             complement(11175..12644)
                     /gene="dtpB"
                     /locus_tag="IRB70_003642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptide/tripeptide permease DtpB"
                     /protein_id="HBC0633506.1"
                     /translation="MNTTTPMGMLQQPRPFFMIFFVELWERFGYYGVQGVLAVFFVKQ
                     LGFSQEQAFVTFGAFAALVYGLISIGGYVGDHLLGTKRTIVLGALVLAIGYFMTGLSL
                     LKPDLIFIALGTIAVGNGLFKANPASLLSKCYPPKDPRLDGAFTLFYMSINIGSLIAL
                     SLAPVIADRFGYSVTYNLCGAGLIIALLVYIACRGMVKDIGSEPDFCPMSFSKLLYVL
                     LGSVVMIFVCAWLMHNVEVANLVLIVLSIVVTIIFFRQAFKLDKTGRNKMFVAFVLML
                     EAVVFYILYAQMPTSLNFFAINNVHHEILGFSINPVSFQALNPFWVVLASPILAGIYT
                     HLGNKGKDLSMPMKFTLGMFMCSLGFLTAAAAGMWFADAQGLTSPWFIVLVYLFQSLG
                     ELFISALGLAMIAALVPQHLMGFILGMWFLTQAAAFLLGGYVATFTAVPDNITDPLET
                     LPVYTNVFGKIGLVTLGVAVVMLLMVPWLKRMIATPESH"
     gene            complement(12960..13394)
                     /gene="uspA"
                     /locus_tag="IRB70_003643"
     CDS             complement(12960..13394)
                     /gene="uspA"
                     /locus_tag="IRB70_003643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspA"
                     /protein_id="HBC0633507.1"
                     /translation="MAYKHILIAVDLSPESKVLVEKAVSMARPYNAKVSLIHVDVNYS
                     DLYTGLIDVNLGDMQKRISEETHHALTELSTNAGYPITETLSGSGDLGQVLVDAIKKY
                     DMDLVVCGHHQDFWSKLMSSARQLINTVHVDMLIVPLRDEEE"
     gene            13785..14120
                     /gene="uspB"
                     /locus_tag="IRB70_003644"
     CDS             13785..14120
                     /gene="uspB"
                     /locus_tag="IRB70_003644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspB"
                     /protein_id="HBC0633508.1"
                     /translation="MISTVALFWALCVVCIVNMARYFSSLRALLVVLRNCDPLLYQYV
                     DGGGFFTSHGQPNKQVRLVWYIYAQRYRDHHDDEFIRRCERVRRQFILTSALCGLVVV
                     SLIALMIWH"
     gene            complement(14191..15690)
                     /gene="pitA"
                     /locus_tag="IRB70_003645"
     CDS             complement(14191..15690)
                     /gene="pitA"
                     /locus_tag="IRB70_003645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitA"
                     /protein_id="HBC0633509.1"
                     /translation="MLHLFAGLDLHTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMRSQLAVVMAAVFNFLGVLLGGLSVAYAIVHMLPTDLLLNMGSSHGLAMVFSMLL
                     AAIIWNLGTWYFGLPASSSHTLIGAIIGIGLTNALMTGTSVVDALNIPKVLSIFGSLI
                     VSPIVGLVFAGGLIFLLRRYWSGTKKRARIHLTPAEREKKDGKKKPPFWTRIALILSA
                     IGVAFSHGANDGQKGIGLVMLVLIGVAPAGFVVNMNATGYEITRTRDAINNVEAYFEQ
                     HPALLKQATGADQLVPAPEAGATQPAEFHCHPSNTINALNRLKGMLTTDVESYDKLSL
                     DQRSQMRRIMLCVSDTIDKVVKMPGVSADDQRLLKKLKSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVATTIGEKIGKKGMTYAQGMSAQMTAAVSIGLASYTGMPVSTTHVL
                     SSSVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAVLLSGGLYWLSLQFL"
     gene            15922..17124
                     /locus_tag="IRB70_003646"
     CDS             15922..17124
                     /locus_tag="IRB70_003646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBC0633510.1"
                     /translation="MERFDAIIIGAGAAGMFCSALAGQAGRRVLLIDNGKKPGRKILM
                     SGGGRCNFTNLYVEPGAYLSQNPHFCKSALARFTQWDFIDLVNKHGITWHEKTLGQLF
                     CDDSAQQIVDMLVDECEKGNVTFRLRSEVLSVAKDETGFTLELNGMTVGCEKLVIATG
                     GLSMPGLGASPFGYKIAEQFGLNVLPTRAGLVPFTLHKPLLEELQVLAGVAVPSVITA
                     ENGTVFRENLLFTHRGLSGPAVLQISSYWQPGEFVSINLLPDVDLETFLNEQRNAHPN
                     QSLKNTLAVHLPKRLVERLQQLGQIPDVSLKQLNVRDQQALISTLTDWRVQPNGTEGY
                     RTAEVTLGGVDTNELSSRTMEARKVPGLYFIGEVMDVTGWLGGYNFQWAWSSAWACAQ
                     DLIAAKSS"
     gene            complement(17439..18491)
                     /locus_tag="IRB70_003647"
     CDS             complement(17439..18491)
                     /locus_tag="IRB70_003647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417948.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2776 domain-containing protein"
                     /protein_id="HBC0633511.1"
                     /translation="MNIYIGWLFKLIPLIMGLICIALGGFVLESSGQSEYFVAGHVLI
                     SLAAICLALFTTAFIIISQLTRGVNTFYNTLFPIIGYAGSIITMIWGWALLAGNDVMA
                     DEFVAGHVIFGVGMIAACVSTVAASSGHFLLIPKNAAGSKSDGTPVQAYSSLIGNCLI
                     AVPVLLTLLGFIWSITLLRSADITPHYVAGHVLLGLTAICACLIGLVATIVHQTRNTF
                     SSKEHWLWCYWVIILGSITVLQGIYVLVSSDASVRLAPGIILICLGMICYSIFSKVWL
                     LALVWRRTCSLANRIPMIPVFTCLFCLFLASFLAEMAQTDIGYFIPSRVLVGLGAVCF
                     TLFSIVSILEAGSAKK"
     gene            18874..20463
                     /locus_tag="IRB70_003648"
     CDS             18874..20463
                     /locus_tag="IRB70_003648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
                     /protein_id="HBC0633512.1"
                     /translation="MKVFHNIFKHISSNHQDKHSDKVNSHQHHGKVDKKHRSKIVEID
                     KLDKHLQIDNDFGLHIIYFLQHGCWNVTEHSSQIEKIWFYNSEPSINIKEYNSFADNT
                     TDTFIFTIIPDNNHVIKLSSPITVTIERKDGYYFINFSGDKSDIIYKVDGFSIIERNF
                     FTLLSGNFKPDWRWAVSKETFTKEKFDSYVESVFSKIDFYKQCGVINPQNANTAYFGD
                     TDGRVGAVLYALLVSGHIGIREKGWSLLCDLLKHEDMASFAYENKKLKKLFTLLDKRD
                     MFLNELHQHVFLKGDAITPCIFLGDHTGDRFSTIFGDKYILTLLNSMRNMEGNKDSRI
                     NKNVVVLAGNHEINFNGNYSARLANHKLSSGDTYNLIKTLDVCNYDSETKVLTSHHGI
                     IRNEENECYCLGALQVPFNQMKDPIDPEELANIFNKKHKQHMDDRLIHLIRSNAIAST
                     PVYDNYFNNTTAFRPKPEDIFKCGQTLKKSKQKYGHYGLGVDQHQKIDNYIMGLNSWK
                     IAPNERGDKKGVPGLSCFQPH"
     gene            20725..>21423
                     /locus_tag="IRB70_003649"
     CDS             20725..>21423
                     /locus_tag="IRB70_003649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4049 domain-containing protein"
                     /protein_id="HBC0633513.1"
                     /translation="MKLGTVAGTNDSITTIATNDMVQEHVTNFTKELFGYIANGIGDD
                     ISSIARTMLGEVVEKIDDWQIERFQQSFQDDKISFTIETNHSEKYSMLSGMRAHILRR
                     NNSYQFIVTINSKNYGCPLDDTDINWCSIVYLLNNMTVNDNANDVAVTESYKPIWDWK
                     ISQYNVSDIKFETIIKPQFADRIYFSNCSPVDPTSTRPTYFGDTDGSVGAVLYALFAT
                     GHLGIMAEGVNFLSQ"
BASE COUNT         5825 a         5030 c         5227 g         5341 t
ORIGIN      
        1 ttgtcaacat attgttcatc tttatgtaaa tttgtgatgg ggttttcctt atgtgaaaaa
       61 atagtatcaa ataaatttgc gtcagtgaag tttacattaa gtagatcttc gaaataaaac
      121 cttgacaagg ttagaacgaa cccggacagg tcctgtcctg tcatattgaa atcaataaag
      181 ttggttccag caaagacttt catcctgttt tcattttcac tgtgctcaat atacaacctt
      241 gtcatttttt ggtacaagcg ttgaatatct tttatatcag ttggtaaatc agttcgttgc
      301 ccagaaaaat ttttattttc ggaagaaacg gtttggacac tgaatcttac tggtattccc
      361 tcttctacga gaattttagt tatgattggc ttattgggct taggattaaa gacaacaatg
      421 attttagatt cagagttttt attcttttcg tatctaatgt tattaatctg attaagtatt
      481 gattgtgtct gttgcgtaag tggtgtcgaa cttatcgttt caatgttatt aataagtttt
      541 acaagttgag ccacaacttt tgagtagtct gcatttgtat atgtggtgtt cgtgtggcac
      601 gcattaattt gttggagttg ttgttgcgct aaatcaaatt gttcagcgtt atatccttct
      661 tcagacaatg aaaaattaat gggttgctgt tcttcctgat tatcacaagg ccacatcggt
      721 gtgtctggtg ttttagcatt gtcggtatct gttgtgcggt tataaatatc gccgtgatat
      781 gtatttatca tacctggggt aaagtcaatt gacataacat tccttattgt tcatctattt
      841 cgctaaattt ttgtaaatcg gagaattaga gcaggaatgg attttcttct acgcggaaat
      901 aaacacaatg cgtcatatct tcctgatata attaccttta acttcccttt catttccacc
      961 aggtaatatt tgtgtataaa aaaagggcag tgatagtatc gtaaaggaaa acgttaacaa
     1021 ctatcaaaaa gcgctcattt taagaagtta tgatgttctc cgatagtgtg tgaagtgata
     1081 tttttgtgat gttttagatg tgtaataatg agccaggtta aagtgtattt aaaaatgtgt
     1141 tgtattggcg actgaaatct accctttaaa agggggatga tactgagaca aagagacatt
     1201 gcttctccga taaaatgtca gagaagcatg attgcgtggt gattgtcgat tgatgactta
     1261 ctgacggatc cgtcatcatt ctcaaagcat tagttaagtt atttgttatt tttaaggatt
     1321 atcctatcta tgattttcta ctcagaagga taaggcactc acaatactcc ttatagttta
     1381 ctgctggcat ctatttaaaa tagcatttga gtcaaatagc ccatcaagat agccatacct
     1441 aagataaccg tcaggaatgc aactatcatc ggtattctga acattgattt aagtaatatc
     1501 acttccgtca ggcttgcgcc ggcactgccg atgattaatg ccattaatgc tcccagaccc
     1561 attccttttg tcatcaaaac agatgccaga gggataactg cctctgcccg gatatatagc
     1621 ggaataccaa caacggcgct caatgggatg gcgaagggat tatctgcccc tgcatgagcg
     1681 gcaatccact ctgagggaat aaagccataa ataaaagagc ctattaatac ccccaacaaa
     1741 agatatggca gtacatcttt aaactgttgc aacgcatctt tggtggctag ttttatggga
     1801 ttaatactta ccacagcttt ggtattgcaa cagttaacta cgggtttctc aatggcttta
     1861 gccgttggac tacagcaact cacttctatt ggcgtatatg tcgtccccgg cgaagttttg
     1921 gctggagcac aacaatttgc tgatgagctt ttactggcaa tgatatgacg ttcaaatccc
     1981 agggaatcca ggataatact ggcaagtacg gagacgccgg cggcgataat cgcgtacaac
     2041 aaggtaactt tccagccaaa ggtcacccac attaacccga cgataatggg attaagtaat
     2101 ggggaaacaa ataaaaaagt gagggtcgga ccaaacccgg ctttcgctga taacaatcca
     2161 cgtaacatgg ggattgtcga gcaactacag aacggggtaa cggctcccaa cagagcagcc
     2221 aggagatagc ctctcccttt tctggccccc atcatctgct ggattttatg gtctggcacc
     2281 ttttgtctta tcaggctcac accggcacta atcactataa acagcaaaga aagctcgacg
     2341 gcgagaaaca caaacatctc tgcggcatct tgcagcatcg caagccaact actcatacgt
     2401 aacctcattg aataaatcta tatttccaga ataatcgaaa tgaaattcaa atcaagatat
     2461 ttctggtatt atcgaaatat caaccagaca gaggggagtc atatgcagtt ggaagaagtt
     2521 gctaaagcgc tgaaagagct aggtcacccg acccgtttgt tcatatttaa gcatctggtc
     2581 aaagcggggg aacaaggttt gccggtcggt gagttgcaaa agcagcttgg gatacccggc
     2641 tctacactca gtcaccatat ctcagcactg gtatcggtag gactggtcaa acaaaaccgt
     2701 gagagtcgga cgctgatgtg tgtttcgcaa tatgcaatgc tggaagcgat aattgaattc
     2761 ttacgcgagg agtgctgcgt aaacagcaaa acagatggcg aaggggccac gaagaacaaa
     2821 taagggggca tatccccctt tagctatttc aggcgcttac ccgcctcatc aaccactttc
     2881 tcgccatctt ccttggtgaa cgcgcgttgt tgcgcatctg gcagaatttc cagcaccact
     2941 tctgaagggc ggcacaggcg agttcccagt ggcgtcacca caatcgggcg attaatcaga
     3001 atcgggtgct gaagcataaa gtcgattaac cgatcgtcag taaatttatc ttctgcaagg
     3061 cccagttcct catacggctc gacgttttta cgcagcagcg cgcgtacgga aatccccata
     3121 tcggcaatga gtttgaccag ttcatcacgc gtcggtgggg tttccagata ataaacaatg
     3181 gtcggttctg tgccgctgtt gcggatcatc tccagcgtat ttcgcgacgt gccgcaggct
     3241 gggttgtgat aaatagtaat gttgctcata tcagtatctc attacaaagt gaaagagaga
     3301 cgaagcgcca gcgcggcgag cgtcacaaac agcaccggca gggtcatgat aatccctgta
     3361 cggaagtaat atccccagct gatagtcata ttcttctgcg aaagtacgtg cagccagagc
     3421 agcgttgcca ggctaccaat cggtgtaatt ttcggcccca aatcgcagcc aatcacgttg
     3481 gcataaacca tcgcctcttt gatgacacca gacgccgtgc tgccatcaat ggacaacgcg
     3541 ccaaccagta ccgtcggcat attgttcata atagaagaga ggaaggcggt gaggaatccg
     3601 gtaccgagcg tcgccgccca caggccgtta tccgccagca cgttgagtac gccagaaaga
     3661 tattccgtta gtccggcatt gcgcaggcca taaaccacca gatacatgcc gagcgagaag
     3721 atgacaatct gccagggcgc accgcgtagc accttacccg tattaatcgc atgaccgcgt
     3781 ttagcgacga caaataatat cagcacgccc actgccgcaa tggcgcttac cggaatgccg
     3841 agcggttcca ggacgaaaaa tcccaccagc agaagcagta aaacaaccca gccagctttg
     3901 aacgtagcag gatctttaat cgcttctgcg ggagatttca gcagcgccat gtcgtagttc
     3961 tgcggaatat ctttgcggaa atagagatgc aacatcacca gggtagccag tattgcagcg
     4021 atatccaccg gcaccatcac cgaggcgtat tcgcgaaagc cgaggtcaaa gaaatctgcc
     4081 gaaacgatat tcaccagatt agagacaata agcggcaggc tggcggtatc ggcaatgaat
     4141 ccggccgcca tcacaaacgc cagcgtagtg cctttgttga accctaaagc cagcagcatg
     4201 gcgatgacaa tcggtgtcaa aataagcgcc gcgccatcat tggcaaacag agctgcaacg
     4261 gtagcaccga gcaggacaat ccaggtaaac agcaagcgac cgcgcccatt gccccagcgt
     4321 gagacgtgca gcgcagccca ttcaaaaaag ccggactcat ccagcagcaa gctgatgata
     4381 atgacggcga taaacgccgc cgtcgcgttc cagacgatat tccacaccac cggaatatcg
     4441 cccggatgga ccacgccagt aactaacgcc agtacggcgc ccagtgtcgc actccagccg
     4501 atgcctaaac ctttcggctg ccagataacc aatacgatgg tcaggacaaa aatagcgcct
     4561 gccagtaaca tcatgcctcc tggataaaac acattcgaat attcatatgt gtttagataa
     4621 attttttaac tacaaatatt cttactgtct gcggaacaat tttgtctggc gaggttacgg
     4681 acaatcacct gaaccttttc ctgttcgcat cgccaggcct gctcaataat tttcgccgcc
     4741 catgctggaa tatgcggcga taaacggtaa tgaacccact ttccttgctt gcggtccagc
     4801 aatagcccac tttcacgcag taatgccaga tggcgggaga tcttgggctg cgactgatcg
     4861 agggcagtgc agagatcgca gacgcataac tctcccagct cgctgagcag taaaacgatg
     4921 cccaaacggg tttcatcggc aagaattttg aagagttgga tgggtaacag aaatgacata
     4981 ttgcgctcct gattgttgca cttagtgtct ctcttcgaag cggataagtc aaaaacatat
     5041 atggtttaac gaatgcgtat gtgcagagga aggtaataga tgtgagttaa gagttgggta
     5101 tttattggaa aagacctgaa tcaggacgta aaaaaaccga ctttgcgtcg gttttttact
     5161 ttccagccct gagttggtgg ctctggctgg agtgagagag ctcttatcta acggttcaat
     5221 actattagcc agtggctaac attgcaagaa ttagcgattt cttcagctgg cggagggggc
     5281 acttcggtat atatcgcagt gacgatttat atactttcac tgggtcatcg tcatattaag
     5341 ccttgtccga atccggatgt aaaaaaaccg actttgcgtc ggttttttta ctttccagcc
     5401 ctgagttggt ggctctggct ggagtgagaa tgccatcatc taacgcatca atgctaatac
     5461 catactgaaa ctattgcaag gacatgctgg ttttataacc tgaatatact gtatgattat
     5521 ccagttagct ctgaggcatt ttcactctgg caatgcgcat aaacgctttc aaagtcctga
     5581 acagtggtac gggtggtgcc gttaactgat gctctggccg gagtgagaat gccattatct
     5641 aacaataggg catgcgccgt gacaggcaat ggatgagtaa gcggatgcat tctcactcca
     5701 tcgtatggag aacacgggtg attgataaag caatcatcgt tcttggggcg ttaattgcgc
     5761 tgctggaact gatccgcttt ctgcttcagc ttctgaactg atagcggaaa cgtagctaag
     5821 ggctaagagc acactactct tagcccttta acatttaacg catggtaacg aactcttctg
     5881 ccgctgtcgg gtgaatggca accgtgttgt cgaagtcttt tttggttgca cccatcttca
     5941 gcgccaccgc gaagccctgc aacatttcgt ccataccaaa accaatgccg tgaataccga
     6001 caatcttctc ttccggccca acgcatacca gtttcatgcg gcacggctgg cggtgagtgg
     6061 tgacggcggt atacatcgcg gtgaaagagg atttatacac tttcacctga tcgtcgccgt
     6121 actgctcgcg cgcctgcggc tccgttaaac caacagtacc aatcggcgga tggctgaaga
     6181 ccacggtcgg aatgttgctg taatccagat gctcatccgg cttgttatta aacaggcgtt
     6241 cagagagacg gcgacccgcg gcaactgcta ccggtgtcag ttccactgcc cccgtgttat
     6301 cgcccaccgc gtagatacct tcaacgttgg tattttgata tttatcgacg acgatatacc
     6361 ctttttcgtt agttttaacg ccagcggctt ccaggttgat gttgtcattg gcaggctcgc
     6421 gaccaatcgc ccaaatcagg caatccaccg tttcactgcg gccatcttcc agctccagcg
     6481 tcaggctacc atcagcattt ttcactactg ctttcgggat ggcgttggtg tgcaactgcg
     6541 ggccttcagc gttcatcact tcgaccagcg tttcagagat catcgggtca aagctgcgca
     6601 gcggcgcatg tttacgcaca aacagatgcg ttttcgcgcc gaggccgtta atcacgcccg
     6661 ccagttccac ggcgatgtaa cccgcgccaa caaccgccac gcgctctggc aaagcaggaa
     6721 gggcgaagaa gccatcagaa tcaataccgt attccacgcc cggaatatcc gggtggctcg
     6781 gacgaccgcc ggtggcgatc agaatatgat cggccgtgat ggtttcaccg ttaacttcca
     6841 gcgttttggc atcaacgaag cgggcaaagc ctttgattac atcaacgtta tttttaccga
     6901 gcacgttttc ataggaggta tgaatacggt cgatataggc ggtacggctg gcgatcaacg
     6961 tttcccagtt gaacttgttg atggtggtat cgaaaccata atccgggccg tacatatgga
     7021 tcgcttcacg gatttgcgcc gcgtgccaca tcactttttt cggcacacag ccaacattta
     7081 cgcaggtgcc gcccagttct ttggcttcaa tcagcgcgca tttctgaccg tacatagccg
     7141 cgcggttgat ggaggcgata ccgccgctgc cgccgccgat ggcgatgtaa tcatagtgtt
     7201 tagtcatgac agagtgtcct tatcgttgat taccgcgatt gtagcgcgag acgtaatagg
     7261 tgccagcgat ggctgcaatt actccggcac gatccagctg acggtagcgt gaccagtgcc
     7321 tgccggaacc agtttgctgt gcagccacgg cagcacgtta ttcatctgct gttccagctt
     7381 ccacggtggg ttaatcacaa tcatgccgga agcggtcatg ccacggcgat cgctgtctgg
     7441 cagcaccgcc agttcaattt gcagaatttt gcgaatgccg gtcgcttcca ggtcgtggat
     7501 catgcgctta atttgctgac gcagcaccac tggataccac agtgcgtaag tgccagtggc
     7561 gaaacgttta tagccttctg ctatcccgct gaccaccgcc tgatagtcgg ttttcatttc
     7621 atacggtggg tcgataagga ttaaaccacg gcgggaaacc ggcggcagtt tggccttaag
     7681 ctgctggaaa ccatcggctt tttcgacgcg cgcacgattg tctttctgaa attcagaacg
     7741 cagcaacggg taatcgctcg ggtgcagttc ggtcagttgc aggctgtcct gttcacgcag
     7801 taactgacga gcaatcaacg gtgaaccggg gtagtaacgc aactgaccgc tacggttgaa
     7861 gtgttttacc acattgatgt acgcctccag ctccgcaggc aaatcgtcct gctgccagat
     7921 acgggcgata ccttcgagat attcgccggt acgctcggca tgttcgctgc ctaactgata
     7981 acgcccggcc cctgcgtggg tatcgagata gagaaacggt ttatctttct ctttcagcga
     8041 ctcgatgatc aggctctgaa cggtatgttt aaggacgtcg gcgtggttgc cagcgtgaaa
     8101 gctgtggcga taactgagca tgggtaaagg tgttccggta agtaaaaatc ggcccgtatt
     8161 cggggcgcac aaaagcctat caggacagta taccgaaaag aggccgccgc cgcgaaagcg
     8221 taacgtttct cattgaaatt cactacactt aaccccatgc tacacacatt atgtaaagcg
     8281 ccagttgagc gcttccttaa cctctttaac caggactgcg ctaatgacga atccgttact
     8341 gactcccttt gaattgcctc cgttttctaa aattctcccg gaacatgtcg ttcctgccgt
     8401 gactaaggcg ctgaacgact gccgcgaaaa tgtggagcgc gtagtagcgc aaggagcacc
     8461 gtacacctgg gaaaatctct gccagccgtt ggcggaagtg gacgatgtgc tggggcgtat
     8521 cttctccccg atcagccacc tgaactcggt gaaaaatagc ccggaactgc gtgaagcgta
     8581 cgaacaaacc ctgccgctgc tgtcggaata cagcacctgg gttgggcaac atgaaggact
     8641 gtataaagcg tatcgcgacc tgcgcgatgg cgatcattac gccacgctga acacggcgca
     8701 gaagaaagcg gttgataacg cactgcgcga cttcgaactc tctggcatcg gtctgccgaa
     8761 agagaagcag cagcgttatg gcgaaattgc cacccgtctt tccgagctgg gcaaccagta
     8821 cagcaacaac gtcctcgatg cgacaatggg ctggaccaaa ctcgttaccg acgaagcgga
     8881 gctggcgggg atgccagaaa gcgcgctggc tgcggcaaaa gcccaggctg aagcgaaaga
     8941 acttgaaggc tacctgctga cgctggatat cccaagctac ctgccggtaa tgacctactg
     9001 cgacaaccag gctctgcgcg aagagatgta tcgcgcttac agcacccgcg cctccgatca
     9061 aggtccgaac gccggtaagt gggacaacag caaggtgatg gaagagatcc tcgcgctgcg
     9121 tcacgaactg gcgcaactgc tgggctttga aaactacgcc tttaaatccc ttgctactaa
     9181 aatggcagaa aatccgcagc aggtgctgga tttcttaacc gatctggcaa aacgcgcgcg
     9241 tccacaaggc gaaaaagagc tggcgcaact gcgtgccttc gccaaagccg aatttggcgt
     9301 cgatgagttg cagccgtggg atatcgcata ctacagcgaa aaacagaaac agcacctcta
     9361 cagcatcagc gacgaacaac tgcgtccgta cttcccggaa aacaaagcgg ttaacggctt
     9421 gtttgagatg gtgaaacgta tttacggcat caccgctaaa gagcgtaaag atgttgatgt
     9481 ctggcatccg gatgtccgtt tcttcgaact gtatgacgag aacaacgaac tgcgcggtag
     9541 cttctacctc gacctgtatg cccgtgaaaa caagcgcggc ggggcgtgga tggatgactg
     9601 cgtaggccag atgcgcaaag ctgacggttc tctgcaaaaa ccggtcgcgt acctgacctg
     9661 taacttcaac cgcccggtga atggtaaacc ggcgctgttt actcatgacg aagtaatcac
     9721 gctgttccat gagttcggtc acggcctgca tcatatgctg acccgcatcg aaaccgccgg
     9781 tgtatccggg attagtgggg tgccgtggga tgcggtcgaa ctgccgagcc agtttatgga
     9841 aaactggtgc tgggagcctg aggcgctggc gtttatctcc ggtcactatg aaaccggcga
     9901 accgctgccg aaggagctgc tggataaaat gctggcggcg aagaactacc aggcggcgct
     9961 gtttattctg cgccagctgg agttcggcct gtttgatttc cgcctccatg ccgagttccg
    10021 cccggatcag ggagcgaaaa tcctcgaaac tctggcagaa atcaagaaac tggttgccgt
    10081 agtaccgtct ccatcctggg gccgtttccc gcacgctttc agccatattt tcgccggtgg
    10141 ttatgccgca ggttactaca gctacctgtg ggccgacgtg ctggcggcag atgccttctc
    10201 gcgctttgag gaagagggca ttttcaaccg tgaaaccgga cagtcgttcc tcgacaacat
    10261 tctgagccgt ggcggttcag aagagccgat ggatctgttc aaacgcttcc gtggtcgtga
    10321 accgcagctg gatgcgatgc tggagcatta cggcattaag ggctgatcat tcagtgaaaa
    10381 tctgcttaat tgatgaaaca ggcaccggag acggtgcctt atctgttctg gcggcccgct
    10441 gggggctgga acacgatgaa gacaacctga tggcgctggt gttaacgccg gagcatctgg
    10501 aactgcgcaa gcgtgatgag ccaaaacttg gcggcatctt tgttgatttt gttggcggag
    10561 cgatggcgca ccgacgcaaa ttcggcggcg gacgtgggga ggcagtggcg aaagcggtgg
    10621 gcattaaagg cgattatttg ccggatgtgg tggatgccac tgcagggctg gggcgcgatg
    10681 cctttgtgct ggcttcagtc ggctgccgcg tgcggatgct ggagcgtaat ccagtcgttg
    10741 ctgcattgct cgacgacggc ctggcgcgtg gttatgcgga tgcggaaatc ggcggctggt
    10801 tgcaggagcg tttgcagtta attcacgcct ccagcctgac ggcgctgacc gatattaccc
    10861 cgcgcccgca ggtggtttat ctcgacccga tgttcccgca taagcagaaa agcgcgctgg
    10921 tgaaaaaaga gatgcgcgtc tttcagtcgc tggtggggcc ggatcttgat gccgatggat
    10981 tgctggagcc tgcacgcttg ctggcgacca aacgcgtggt ggtaaagcgc ccggactacg
    11041 cgccgccgct ggcgaatgtc gccacgccaa acgcggtagt gaccaaaggg catcgctttg
    11101 atatttatgc cggaacgccg gtgtaaaagt aaagcagggt agcgttatcg ctaccctgct
    11161 ttctgcaaga ataattaatg gctttcgggt gtcgcaatca tgcgtttcag ccacggcacc
    11221 atcagcagca tcaccaccgc aacgcccagc gtaaccaggc caatcttacc aaacacgttg
    11281 gtatagacgg gcaacgtctc aagcggatcg gtaatgttgt ctggtactgc ggtaaatgtt
    11341 gccacatagc cgcccagcaa gaacgcggca gcctgcgtca ggaaccacat cccgagaata
    11401 aagcccatca aatgctgcgg caccagggca gcaatcatcg ccaggcccag ggcgctaata
    11461 aacagttcac ccaggctctg gaataagtac accagcacga taaaccatgg cgatgtcagc
    11521 ccctgggcat ccgcaaacca cattccagcc gctgcagccg tcaaaaagcc cagcgagcac
    11581 ataaacattc cgagagtaaa tttcatcggc atcgagaggt ctttgccttt gttacccaga
    11641 tgcgtgtaaa tgcctgccag tattgggctg gcgagtacca cccagaacgg gttaagcgcc
    11701 tggaagctga ccgggttgat ggaaaagccg agaatttcat gatgcacgtt gttgatggca
    11761 aagaagttca gcgacgttgg catctgggcg tagagaatgt aaaacaccac cgcttcgagc
    11821 atcaggacaa aggcgacaaa cattttattg cgcccggttt tatccagctt gaatgcctga
    11881 cgaaagaaaa tgatggtgac gacgatggag agaacaatca gcaccagatt ggcgacttct
    11941 acgttgtgca tcagccatgc acagacgaag atcatcacca cgctgccaag taacacgtac
    12001 aacagtttac tgaagctcat cgggcagaag tcgggttcag aaccaatatc tttcaccatt
    12061 ccgcgacagg cgatgtaaac caatagcgcg ataattaatc ccgcaccgca caggttgtag
    12121 gtgactgaat agccgaatct atcagcgatc acaggggcca gcgataacgc tatcaacgag
    12181 ccgatgttga tcgacatata gaacagggta aatgcgccat caagccgcgg atctttcggc
    12241 ggatagcact tcgaaagcaa gctggctggg ttagctttaa acaggccgtt accgacagcg
    12301 atagtcccca gggcgatgaa aatcaggtca ggcttaagta gcgacaggcc ggtcatgaag
    12361 tagccaatcg ccagcacaag tgctccgaga acaatggtgc gtttggtccc cagcaggtgg
    12421 tcgccgacat agccgccaat ggaaatgagg ccatagacca gcgcagcaaa agcaccaaaa
    12481 gtgacaaaag cctgttcttg cgagaatcca agctgcttaa cgaagaaaac agccagtacg
    12541 ccctgcacgc cgtagtagcc gaatcgctcc cataactcga caaaaaagat catgaaaaat
    12601 gggcgaggtt gctgcagcat ccccatgggt gttgttgtat tcatatttat taaccttcca
    12661 ataccatcct gaaaagtatg aacgcgtaag ggataacgcg cgaaaaagtt tacatctgtc
    12721 agagattctt aatattgatg cggtgaatag attaatacac tattacaaca gaaaataacc
    12781 agctgatcac actaatgatg gaaaatatga tggtgttaaa tgttgtattg gcaggggatt
    12841 ttgattgcgt acgcagaccg taggccagat aaggtgttta cgctgcaagg taacaaggcg
    12901 cgccaaaaag caaaacgccc gcatatgcgg gcgttcagga acacgtcgta gagggaagat
    12961 tattcttctt cgtcgcgtag cggaacaatc agcatatcaa cgtgaacggt gttgatcagc
    13021 tgacgtgcgg aagacatcag tttgctccag aagtcctggt ggtgaccaca aaccaccaga
    13081 tccatatcgt atttcttgat tgcatcgacc agaacctggc ccaggtcgcc gctgccgctc
    13141 agggtttcag tgattgggta gcctgcatta gtggaaagct cggtcagcgc atgatgtgtc
    13201 tcttcagaga tgcgtttctg catatcaccc agattcacat caataagccc ggtgtatagg
    13261 tcagagtagt ttacatctac gtggatcaga gaaactttcg cattgtaggg gcgagccata
    13321 gagactgctt tctctaccag aactttgctt tccggggaga ggtcgaccgc gatgagaatg
    13381 tgtttataag ccatagtgtt actccttcca taaagttgtc gatgactggc cagctagcgt
    13441 ttcttgtgcc gttacgtcac ccgcgtcctg cgaactacgt gcgcggggct aacccagccg
    13501 taaagattca gtgttaagac catccttacc ttatagcgac ccggatgatc cgtcaatccg
    13561 ccttgcttac tcgttagata aacaaatttt cgacatgaat atattgatag tggttaacct
    13621 tctggaaaaa aaacaacctg atctcctaca ctatctatag agccgctcgg atgttggtca
    13681 ccacaaaagc ggtttctcca ggacctggtg ttaactgatt ggcagcgtat cgggagcggt
    13741 agccccgggg tggaactccg cgggcaggtc gccggggagg aggtatgata agcaccgtcg
    13801 cattattttg ggctttatgt gtcgtttgca ttgttaacat ggcgcgctat ttctcatcac
    13861 tacgcgcgtt gttagtggta ctgcgtaact gcgatccatt gctctatcaa tatgttgatg
    13921 gagggggctt ttttacctca catggccaac ccaacaaaca ggtgcgtctc gtttggtata
    13981 tctatgccca acgttatcgc gatcatcacg atgatgagtt tattcgccgc tgtgagcggg
    14041 tgcgtcggca gtttattctg accagcgcat tgtgtggtct ggtggtggtc agcctgattg
    14101 cattgatgat ttggcattaa gcacttcagc aataatgacg cataaaaaaa gcgggccagt
    14161 aaactgaccc gctcgttttg gtgcgtacga ttacaggaac tgcaaggaga gccagtacag
    14221 cccgccggaa agcagtaccg cagccggaag ggtaaatacc caggccatca gaatactggt
    14281 tacggtttta cgctgtaagc cgccgccatc taccaccatc gtccccgcga cagaagagga
    14341 gagtacgtga gtagtggaaa ccggcatccc ggtataactt gccaggccga tagacactgc
    14401 cgccgtcatc tgggcagaca tcccctgagc gtaggtcatg cctttcttac cgattttctc
    14461 accgatagtc gttgccacac gacgccagcc aatcatcgta ccgataccta acgccagcgc
    14521 gaccgccatg atgatccaca ccggcgcgta ctcgatggtg ctaagcatgt cggacttcag
    14581 tttcttcaac agacgctgat cgtcagcact cacaccaggc atcttcacca ctttatcgat
    14641 agtgtcagaa acgcacagca taatgcggcg catctggcta cgttgatcaa gcgacagctt
    14701 gtcgtagctt tccacatcag tagtcaacat gcctttcagg cggttgagcg cgttaatggt
    14761 attcgacgga tggcaatgga actccgcagg ttgcgttgcg ccagcttccg gagccggtac
    14821 taactgatca gcaccggtag cctgtttcag cagcgcaggg tgctgctcaa agtaagcttc
    14881 cacgttgttg atggcatcac gggtacgggt gatttcgtag ccagtggcat tcatgttcac
    14941 cacgaagcct gctggtgcga cgccaatcaa taccaacata accagaccaa tgcctttctg
    15001 accatcgttc gcgccgtgcg aaaacgccac gccgatagcg gaaaggatca gcgcaatacg
    15061 cgtccagaac ggcggctttt tcttgccgtc tttcttttca cgctccgctg gggtcaggtg
    15121 gatacgggcg cgtttcttgg tgccgctcca gtagcggcgc agcaagaaaa tcagaccgcc
    15181 agcaaacacc aggccgacaa taggggaaac gatcagagaa ccgaaaatac ttaatacttt
    15241 cgggatattg agtgcatcca ccactgacgt cccggtcatc aacgcattgg ttaaaccaat
    15301 cccgatgatc gcgccaatca gcgtatgaga gctggatgca ggtaaaccaa agtaccaggt
    15361 acccaggttc cagataatcg ccgccagcaa catagagaac accatggcaa ggccatgaga
    15421 cgatcccata ttaagcagca gatccgtcgg cagcatatgc acaatggcat aggcaacact
    15481 cagaccaccc agcaaaacac ccaaaaagtt gaacaccgcc gccataacca cggcgagctg
    15541 agaacgcatc gcgcgggtat agataacggt tgccacggcg ttggctgtgt catggaaacc
    15601 attgatggct tcgtagaaca gcacaaaagc cagtgcaagc aataataaca gcccggtatg
    15661 caaatccagg ccagcaaaca aatgtagcat aggacgttac gccattttga ggacatgaac
    15721 gcggcgcatt atcagtgact ttcgcggcgc gggcaaagtg aaatatagac tttttttgat
    15781 ttgcctcctg tatggatttc actcaaaaaa taattatctt atataattca ggcaaatact
    15841 tccttttagt aatattgatg ctggtgcgac cactgaggaa tctttacaat tcacgcccgt
    15901 tttttcttag aggagcgcaa cgtggaaagg tttgatgcca ttattatagg cgctggtgcg
    15961 gcaggtatgt tctgttctgc gctggcaggt caggcaggac gccgggttct gctgatcgat
    16021 aatggtaaaa aaccagggcg caaaatcctc atgtctggcg gtgggcgctg caactttacc
    16081 aacctttatg tcgaaccggg cgcttatctg agccagaatc cgcatttttg taagtctgca
    16141 ctcgcgcgtt ttacccagtg ggatttcatt gatctggtca ataaacacgg catcacctgg
    16201 cacgagaaaa cgttagggca actcttctgc gatgactccg cgcagcagat tgtcgacatg
    16261 ctggtggatg agtgcgagaa gggcaatgtg accttcagat tgcgtagcga agtgctgagt
    16321 gtggcgaagg atgaaacagg cttcacgctt gaactgaacg gcatgactgt cggttgcgaa
    16381 aagctggtca tcgcgaccgg tggactgtca atgccagggc tgggcgcgtc gccgtttggt
    16441 tataagattg ccgaacaatt tggcctcaac gtgctgccga cccgcgcggg cctggtgcca
    16501 ttcactctgc ataaaccgtt gctcgaagag ttacaggtgc tggcgggcgt ggcggtgcct
    16561 tccgtgatta ccgctgaaaa cggcaccgtt ttccgtgaga acttactctt cacccaccgc
    16621 ggcttatctg gaccggcggt gttgcaaatt tccagctact ggcaaccggg tgaatttgtc
    16681 agtatcaatc tgctaccgga tgtggacctc gaaaccttcc tgaatgagca gcgtaatgca
    16741 catccgaatc agagcctgaa aaacacactg gcggttcatc taccgaagcg gttggttgaa
    16801 cgtttacagc aactcgggca aatcccggat gtttcgctaa aacagctcaa cgtgcgtgac
    16861 caacaggcac tgattagcac attgaccgac tggcgcgtac aacccaacgg cactgaaggc
    16921 tatcgtactg ctgaagtgac gctcggcggc gtggacacca acgaactctc ttcacggacg
    16981 atggaagcgc gcaaagtgcc tgggctgtac ttcatcggcg aagtgatgga cgtcaccggc
    17041 tggctggggg gctataattt ccagtgggcg tggtcgagtg cgtgggcttg tgcgcaggat
    17101 ttgattgcag cgaagtcgtc ctgagctatt tcctaaagat gaaaattatt agagtcgcat
    17161 taaaaatgag ctaattttga tagtggttat cttgtgatta ttttctaatg agcctgtgaa
    17221 ctgaaaccct ccatgcttaa tataaggtgg agggaaaggt gattaaaact cccccagtgg
    17281 ccagatcttt ataaaatatg aacaggttga aaaaatcagc aactttgctg tttatttata
    17341 cttaaccact atgcattaat gctgcgttat ttcatgatac ctaagaaaaa ccagcgttac
    17401 gcaaataatc aacgctggtt ttatccggta cgttgcaatt attttttagc agaacccgct
    17461 tctaatattg aaacgattga gaacaacgta aagcataccg ctcccaaacc gaccagaacc
    17521 cgcgaaggaa taaaataccc tatgtcggtc tgcgccattt ccgcaagaaa cgatgccagg
    17581 aaaaggcaaa acaggcaggt gaagacggga atcatcggta ttctgttggc taacgaacag
    17641 gtacgtctcc agaccagtgc cagtagccag acttttgaga atatgctgta acagatcatt
    17701 ccgaggcaaa tgagaataat gccgggagcc agtcggacgc ttgcatcgga gctgactaac
    17761 acgtatatgc cctgcagcac cgtgattgag ccgagaataa taacccaata acaccacagc
    17821 cagtgttctt tggatgagaa cgtattacgt gtttgatgga cgattgtggc aacaaggcca
    17881 attagacagg cacagattgc ggttaaccca agcaatacgt gaccggcgac ataatgcgga
    17941 gttatgtcgg cactacgtaa cagcgtaata gaccaaatga aaccgagcag ggtgagtaaa
    18001 acgggaacgg caatgaggca attaccgatt aatgacgaat aagcctgtac cggtgttcca
    18061 tcgctcttgc tccctgctgc gtttttggga atgagcagaa agtgaccgga tgacgctgcc
    18121 actgtcgata cacaggcggc aatcatacca acgccaaaaa taacatggcc ggcaacaaac
    18181 tcgtctgcca tcacatcatt gcctgctaac agtgcccaac cccatatcat ggtgataatt
    18241 gaccccgcat agccaataat ggggaacaat gtattgtaaa acgtattaac gccgcgcgtg
    18301 agctgcgaaa tgataataaa tgcggtagtg aataatgcca ggcatatggc tgccagagaa
    18361 atcagcacat gacccgcgac gaaatactca ctttgcccag aactttccag cacaaagcca
    18421 cctaacgcga tacaaattaa gcccataatt aaagggatta atttgaaaag ccacccgata
    18481 tatatgttca ctttaaactc ctcaggtatc cctgctaata ttgaaatgtg cattaatgat
    18541 aatttcagcc tgttaatata atgacgagat atcattaaag acaaatgcat agcataacta
    18601 tagcgggatt tactttgcag agcgctactt ttcagcgttc aaaaggccat ggtaaataaa
    18661 tatttatcct aagattaatt cttattctgt tgttttttac aattatcttc cagggaggga
    18721 ttctttttca ttatttggta aaagaccgga tggtatcggt gcttaaaatc atcgaacata
    18781 taagtattat tgctttgtat catcgtaaat atgtctttca gacatgtgtc atttattttg
    18841 ttactaacaa gtcaaaaata tcacgggtta tttatgaaag tatttcacaa tatatttaag
    18901 cacatctctt caaaccatca agataagcat tcagataaag ttaacagtca tcaacaccat
    18961 ggcaaggttg ataaaaaaca tcgttcaaag atagttgaaa ttgataagct ggataaacat
    19021 ttgcaaatag ataacgattt tggcctgcat atcatctatt tcctgcaaca tggctgctgg
    19081 aacgtaactg aacatagttc tcagatagaa aaaatatggt tttacaatag tgagccatct
    19141 ataaatatta aagaatataa tagtttcgcc gataatacta ctgacacgtt tatctttaca
    19201 attataccag acaataacca tgtgataaaa ttatcgtctc ccattaccgt tacgattgag
    19261 cgtaaggacg gttattattt tattaatttc tccggtgata aatcagacat aatttataaa
    19321 gttgatgggt tttctatcat agagagaaat ttctttactc ttcttagtgg taatttcaaa
    19381 cctgactggc gttgggctgt ctctaaagag acgtttacta aggaaaagtt tgatagctat
    19441 gttgaatctg ttttttcaaa aatagacttt tataaacagt gcggtgtgat taacccacaa
    19501 aatgccaaca cggcttattt tggcgataca gatggaagag taggcgctgt actttatgca
    19561 ttgctcgttt cagggcatat aggcatcagg gaaaaggggt ggagtttatt atgtgattta
    19621 ttaaaacacg aagacatggc ttcattcgca tatgaaaata aaaaattgaa aaaactcttc
    19681 actttattag ataagagaga catgtttttg aatgagttgc atcaacatgt ttttttaaaa
    19741 ggcgatgcga ttaccccttg tatcttcctt ggggatcata caggcgatag atttagtact
    19801 atttttggtg ataaatatat ccttactttg ctaaattcta tgcgaaatat ggagggtaat
    19861 aaagatagtc gtataaataa aaatgtcgtc gttctggctg gaaatcatga aatcaatttt
    19921 aatggtaact atagtgcccg actagcaaat cataaactct cttccggtga tacatataac
    19981 ttaattaaaa cgctcgatgt ttgtaattat gactcagaaa cgaaagtttt aaccagtcat
    20041 cacggaataa taagaaatga agaaaatgaa tgttattgtc taggtgcttt gcaggttcca
    20101 tttaatcaga tgaaagaccc aattgatcct gaggaattag caaatatatt taataaaaaa
    20161 cataaacaac acatggatga tcgtcttatc catctaatta gaagcaatgc tatagcatcc
    20221 acacctgtat atgacaatta ttttaataac actactgctt tcagaccaaa acctgaagat
    20281 atcttcaaat gtggacagac gctcaaaaaa agtaaacaga aatatggcca ttatggatta
    20341 ggggtagatc agcatcaaaa aattgataat tatatcatgg ggctaaattc ctggaagata
    20401 gcacctaacg aacgtggtga taaaaaaggt gtcccagggc ttagttgttt tcaaccacat
    20461 taaaactcca tgagtgctgt ggtatgtctt tttaatcctg ccagtatttc atagtttttc
    20521 ttaatcgatt gtagaggcat gtactgatga cgcctctaca atctttaggg actttctcta
    20581 ctatgagata agaaatttca tattatgctt taaggctgaa tgatttgtgc aaaatataat
    20641 tattttcccg tcgaacatga ggtgtatgtc ataagattaa atgataacta tgtattcctt
    20701 gcggtgaatt atatgaggta aaagatgaaa cttggaactg tggcaggcac taacgacagt
    20761 ataacgacta tcgcaacaaa tgatatggtg caagagcatg ttactaactt cactaaagaa
    20821 ctgtttgggt atattgcaaa tggtataggt gatgatatat caagtattgc caggacaatg
    20881 ctcggtgaag ttgtggaaaa aattgatgat tggcaaatag aacgtttcca acaatctttt
    20941 caagatgaca aaatttcatt taccatagaa acgaatcatt cagaaaaata tagtatgcta
    21001 tcgggcatgc gtgcccatat tctacgtagg aataatagtt atcagtttat tgtgacaatt
    21061 aatagtaaaa attacggttg ccctcttgat gataccgata ttaattggtg cagcattgtt
    21121 tatttactta ataatatgac agtaaatgat aatgctaatg atgttgcagt tactgagtcg
    21181 tacaaaccca tctgggactg gaaaatatcg caatataatg tatctgatat taaattcgaa
    21241 acaattataa aaccccagtt cgctgacaga atctatttct ccaattgttc acccgttgat
    21301 cccacaagta ccagaccaac ctattttggt gataccgatg gctcagtcgg tgcagttttg
    21361 tacgcgcttt tcgcaacggg acatttggga attatggctg aaggagtaaa ttttcttagc
    21421 cag
//
LOCUS       DADXDL010000085        21299 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.085, whole genome shotgun sequence.
ACCESSION   DADXDL010000085 DADXDL010000000
VERSION     DADXDL010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21299
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.085"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(229..792)
                     /locus_tag="IRB70_003650"
     CDS             complement(229..792)
                     /locus_tag="IRB70_003650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBC0633514.1"
                     /translation="MHSQLRERIRLMRARLDNAAPVAEIRAESQLFVTPAPVCDRLVM
                     LAEISNRDHILEPSAGTGAILRAIRDTAPGAMCDAVEINSGLVRYLRENFNGVRVQCG
                     DFMEWLPVQYYSRVIMNPPFSHGQDIRHILRAFSLLRPGGVLVAVCLNGPRQQEKLLP
                     FSDVREELPRGTFAYTDVPTMIIRLRA"
     gene            complement(840..2201)
                     /locus_tag="IRB70_003651"
     CDS             complement(840..2201)
                     /locus_tag="IRB70_003651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3560 domain-containing protein"
                     /protein_id="HBC0633515.1"
                     /translation="MTLAAITMTAPEAASPVQMYRATYSPDDNKLRLYAVSRLDPETY
                     KKVHDAGFRWAPKQALFVAPAWTPGREDVLLSLAGEIEDEDSTLAERQEARAERFTGY
                     SGKRASESAQALDEVERLAAMIPPGQPILVGHHSERRARRDAQRIENGMKRAVMLFER
                     AEYWEERARSALLHAKYKERPDVRWRRIKKIEADLRKAEKTIAQSQKYLTMWRAESLD
                     LNMAKLISSHDHISACFPLDTYPRPAEKSQYEGSRSLWSALDDDIITTEQAREIAIRC
                     HERQIQHQQRWVNHYQNRLIYERAMLDESGGVVTRTQDFEPGGQVFSRGEWLTIIRVN
                     KSNGAVSSVTTPNYSFLGYSGTMKVTPDRITDYKAPSAEEAAVASQAAKRPPVVNYPG
                     EGFREMTKAQWAALPRDCKAVRSVAEAEDHGAYRYRRTMDNNFRLVNVYISDMKITEI
                     PQK"
     gene            complement(2253..2483)
                     /locus_tag="IRB70_003652"
     CDS             complement(2253..2483)
                     /locus_tag="IRB70_003652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633516.1"
                     /translation="MTVSIVSPSAAAVKPRRHPRFRREDIPAPEIDPVLKAFGRHIAR
                     SFHRGRGVHIPAMKNTAFGQVLRTLELKRAFN"
     gene            2997..3245
                     /locus_tag="IRB70_003653"
     CDS             2997..3245
                     /locus_tag="IRB70_003653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001403191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633517.1"
                     /translation="MSRDPPQRRRARARNGVAPYIPAAFCRDAGSAGHGATRVARPER
                     SLQARGFHASDRSDSPKPRQRVRRRLAGAPAAACRSRA"
     gene            complement(3518..3709)
                     /locus_tag="IRB70_003654"
     CDS             complement(3518..3709)
                     /locus_tag="IRB70_003654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633518.1"
                     /translation="MNISTETREILRNYRAVINARRREMGQKPLTTAQIVDEICDFVA
                     NQQAVFLGGHYILQGSRNR"
     gene            complement(3706..4128)
                     /locus_tag="IRB70_003655"
     CDS             complement(3706..4128)
                     /locus_tag="IRB70_003655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 family protein"
                     /protein_id="HBC0633519.1"
                     /translation="MYCTVKEIIREVLDTDVPDSECVFAVVLTRGDVRHIAQDWSLTD
                     DELETVMQRLDDAFEYGADVSVVHGVVRELMEEKRASRQVTVPAVMLEKVMALAGSEM
                     KRLYAVGSENGGDGDAFVREEREAMDVVLQALDGETMS"
     gene            complement(4175..4477)
                     /locus_tag="IRB70_003656"
     CDS             complement(4175..4477)
                     /locus_tag="IRB70_003656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBC0633520.1"
                     /translation="MMPEYQGGFWHFIRLPDGGGYMMPDGDRFHMVNGANWFDRTVSA
                     DAAGIILTSLVINRQLWLYHDSGDAGLTQLYRMRDAQLWRHIEFHPECNAIYAALD"
     gene            complement(5017..5793)
                     /locus_tag="IRB70_003657"
     CDS             complement(5017..5793)
                     /locus_tag="IRB70_003657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633521.1"
                     /translation="MNENSTLNALICRHARNLLLAQGWPEETDVDQRNPNYPGWISIY
                     VRLDAPRLATLLINRHGGVLPPLLASAIQRLTGTGAELVLSGSQWQSLPVLPADGTQV
                     SFPYAGEWLTEDEIRAVLDAVHDAVRSICYQVAEDARRIRAALTTTGQTLLTRQTRRF
                     RLVVKESDHPCWLDEDDENLPVVLDAIVNRGARFSSVEMYLVSECIEHILSSGLACDV
                     LRIPDEPPRRWFDRGVLREVVREARTEIRSMADALAKIRK"
     gene            complement(5844..6278)
                     /locus_tag="IRB70_003658"
     CDS             complement(5844..6278)
                     /locus_tag="IRB70_003658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1380 domain-containing protein"
                     /protein_id="HBC0633522.1"
                     /translation="MYGTCETLCRELAAKYPGDAPLMLVIWSPEEIQALADGMEISLT
                     DHEIRTVLARMEDIPEDQRTESGISSAAVMEIISNVSENRQVTVPAELLASLIQTAEQ
                     ALWKREWAARDNGLAVPECVTRRQAVVNQARTLLKNNTHENN"
     gene            complement(6292..6513)
                     /locus_tag="IRB70_003659"
     CDS             complement(6292..6513)
                     /locus_tag="IRB70_003659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633523.1"
                     /translation="MNYAGHEKLRADVAEVANTMCDLRARLNDMEHRCRFDSDVLVER
                     LTRQTLYRANRLFMEAYTEILELDSCFKD"
     gene            complement(6514..7197)
                     /locus_tag="IRB70_003660"
     CDS             complement(6514..7197)
                     /locus_tag="IRB70_003660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858331.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA methylase"
                     /protein_id="HBC0633524.1"
                     /translation="MSRFVLGNCIDVMTRIPDNAIDFILTDPPYLVGFRDRSGRTIAG
                     DKTDEWLQPACNEMYRVLKKDALMVSFYGWNRVDRFMAAWKNAGFSVVGHLVFTKNYT
                     SKAAYVGYRHECAYILAKGRPRLPQNPLPDVLGWKYSGNRHHPTEKPVTSLQPLIESF
                     THPNAIVLDPFAGSGSTCVAALQSGRRYIGIELLEQYHRAGQQRLAAVQRAMQQGAAN
                     DDWFMPEAA"
     gene            complement(7274..7578)
                     /locus_tag="IRB70_003661"
                     /pseudo
     CDS             complement(7274..7578)
                     /locus_tag="IRB70_003661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052644.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(7582..8484)
                     /locus_tag="IRB70_003662"
     CDS             complement(7582..8484)
                     /locus_tag="IRB70_003662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1281 domain-containing protein"
                     /protein_id="HBC0633525.1"
                     /translation="MHFSGEPAQIAEIKRLASGAVTPLYRRATNEGIQLFLAGSAGLL
                     QTTEDVQFEPCPGLTDAGRGVVSPENIAFTRWLTHLQNGVLLDEQNCLMLHELWLQSG
                     TGQRRWEGLPDEVRETITVHFTAKRGDWCGFWSNEDVSVWWNRLCDNVLPEKTMPFDL
                     LTVLPTRLDVEVNGFNGGVLNGVPSAYHWYTEQYGVKWPVGYEVNISRQGENFIQVDF
                     DTPWCQPESNVVAELSRRFGCTLEHWYAEQGCNFCGWQRYERGELVDVLWGELEWSSP
                     TDDDELPEVTAPEWIVDKVAHYGG"
     gene            complement(9179..10150)
                     /locus_tag="IRB70_003663"
     CDS             complement(9179..10150)
                     /locus_tag="IRB70_003663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family plasmid partition
                     protein"
                     /protein_id="HBC0633526.1"
                     /translation="MKRAPVIPKHTLNTQPVGDTSLSTPAAPMVDSLIARVGVMARGN
                     AITLPVCGRDVKFTLEVLRGDSVEKTSRVWSGNERDQELLTEDSLDDLIPSFLLTGQQ
                     TPAFGRRVSGVIEIADGSRRRKAAALTESDYRVLVGELDDEQMAALSRLGNDYRPTSA
                     YERGQRYASRLQNEFAGNISALADAENISRKIITRCINTAKLPKSVVALFSHPGELSA
                     RSGDALQKAFTDKEELLKQQASNLHEQKKAGVIFEAEEVITLLTSVLKTSSASRTSLS
                     SRHQFAPGATVLYKGDKMVLNLDRSRVPTECIEKIEAILKELEKPAP"
     gene            complement(10150..11316)
                     /gene="sopA"
                     /locus_tag="IRB70_003664"
     CDS             complement(10150..11316)
                     /gene="sopA"
                     /locus_tag="IRB70_003664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid-partitioning protein SopA"
                     /protein_id="HBC0633527.1"
                     /translation="MKLMETLNQCINAGHEMTKAIAIAQFNDDSPEARKITRRWRIGE
                     AADLVGVSSQAIRDAEKAGRLPHPDMEIRGRVEQRVGYTIEQINHMRDVFGTRLRRAE
                     DVFPPVIGVAAHKGGVYKTSVSVHLAQDLALKGLRVLLVEGNDPQGTASMYHGWVPDL
                     HIHAEDTLLPFYLGEKDDVTYAIKPTCWPGLDIIPSCLALHRIETELMGKFDEGKLPT
                     DPHLMLRLAIETVAHDYDVIVIDSAPNLGIGTINVVCAADVLIVPTPAELFDYTSALQ
                     FFDMLRDLLKNVDLKGFEPDVRILLTKYSNSNGSQSPWMEEQIRDAWGSMVLKNVVRE
                     TDEVGKGQIRMRTVFEQAIDQRSSTGAWRNALSIWEPVCNEIFDRLIKPRWEIR"
     gene            complement(11904..12659)
                     /gene="repE"
                     /locus_tag="IRB70_003665"
     CDS             complement(11904..12659)
                     /gene="repE"
                     /locus_tag="IRB70_003665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000852146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein RepE"
                     /protein_id="HBC0633528.1"
                     /translation="MAETAVINHKKRKNSPRIVQSNDLTEAAYSLSRDQKRMLYLFVD
                     QIRKSDGTLQEHDGICEIHVAKYAEIFGLTSAEASKDIRQALKSFAGKEVVFYRPEED
                     AGDEKGYESFPWFIKRAHSPSRGLYSVHINPYLIPFFIGLQNRFMQFRLSETKEITNP
                     YAMRLYESLCQYRKPDGSGIVSLKIDWIIERYQLPQSYQRMPDFRRRFLQVCVNEINS
                     RTPMRLSYIEKKKGRQTTHIVFSFRDITSMTTG"
     gene            complement(13433..14239)
                     /locus_tag="IRB70_003666"
     CDS             complement(13433..14239)
                     /locus_tag="IRB70_003666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase family protein"
                     /protein_id="HBC0633529.1"
                     /translation="MSGSVIHSQSAVMVPAVYSAGQPASLPVAIDYPAALALRQMSMV
                     HDELPKYLLAPEVSALLHYVPDLHRKMLLATLWNTGARINEALALTRGDFSLAPPYPF
                     VQLATLKQRTEKAARTAGRMPAGQQTHRLVPLSDSWYVSQLQTMVATLKIPMERRNRR
                     TGRTEKARIWEVTDRTVRTWIGEAVAAAAADGVTFSVPVTPHTFRHSYAMHMLYAGIP
                     LKVLQSLMGHKSISSTEVYTKVFALDVAARHRVQFAMPESDAVAMLKQLS"
     gene            complement(14240..14545)
                     /gene="ccdB"
                     /locus_tag="IRB70_003667"
     CDS             complement(14240..14545)
                     /gene="ccdB"
                     /locus_tag="IRB70_003667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin CcdB"
                     /protein_id="HBC0633530.1"
                     /translation="MQFKVYTYKRESRYRLFVDVQSDIIDTPGRRMVIPLASARLLSD
                     KVSRELYPVVHIGDESWRMMTTDMASVPVSVIGEEVADLSHRENDIKNAINLMFWGI"
     gene            complement(14547..14765)
                     /gene="ccdA"
                     /locus_tag="IRB70_003668"
     CDS             complement(14547..14765)
                     /gene="ccdA"
                     /locus_tag="IRB70_003668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin CcdA"
                     /protein_id="HBC0633531.1"
                     /translation="MKQRITVTVDSDSYQLLKAYDVNISGLVSTTMQNEARRLRAERW
                     KAENQEGMAEVARFIEMNGSFADENRDW"
     gene            15332..15844
                     /locus_tag="IRB70_003669"
     CDS             15332..15844
                     /locus_tag="IRB70_003669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633532.1"
                     /translation="MTIFKENIVDTSLIGPILTALLAAAGFYCKFWFTRYQASRDQAQ
                     KVSRAIEDVLSKMAALFGQKKPARILREEFSAVIAPLHQEMRILDDMTSRLPLKWLQR
                     EQRHVLYHARWLQRYLDSRRGGSDGDFFLLLHDVAMGTDYQVADILASQHDCKQRRGS
                     QLPVNLKTCP"
     gene            complement(15878..17011)
                     /locus_tag="IRB70_003670"
     CDS             complement(15878..17011)
                     /locus_tag="IRB70_003670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000545985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3800 domain-containing protein"
                     /protein_id="HBC0633533.1"
                     /translation="MHFYVDETGQTGRNLFDKTQPVLSYGVLSSDANLDKVAEADLAV
                     IRKTLGVQRLHAAELGLHRLSDLVDTLLVLQKKHRIRFDIWQVVKRDHAIISFFDQVF
                     DQGMNPAVPWSAYWTPLRYPLLLNLASLFDDELASNAWTARLEAHDERASELFCTVSD
                     ELISRTAASALDHRSKQLITDALNWASANFEQLGYNCKTNKERLRIMPNMIGFQSVLH
                     GICSRLGAPERKASIIVDQQSQFNTTQRELNEFYYQIRDMPWELGPGLPVMNMKNMPA
                     EPLVFQSGTKSAGLELVDIYLWTFKRFMEDKALTKPLSRLVYTNLKTARTNSVSIQSV
                     ASRFKELLGKLPVPSAEIMRLAQELRDFDEARRMPYVVSGSPD"
     gene            complement(17178..17951)
                     /locus_tag="IRB70_003671"
     CDS             complement(17178..17951)
                     /locus_tag="IRB70_003671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000905949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633534.1"
                     /translation="MLILDCSSRTQALHTLSAGFGCSPEKLKKVLLSLDLESIYELNP
                     RQLVDAPQYLREYVCAELGEPGPFTRALWFHGTRTFAGNTFPAGLLALNQSESLAMKM
                     LLDLAPNEMVRTHLKEWDVPGGVPDEMFQLRTGDKIHWGPFGHLVRELHFNASENGLH
                     DYLWLPELVEDVCKAYQKKYGHDLKPHYLSVLHPCIVWFEADIVYEKGVLETALSYAY
                     TSVRDLPPDGNATFGIDCDGKSVSRSAIARIEFLQPGQM"
     gene            complement(17964..18464)
                     /locus_tag="IRB70_003672"
     CDS             complement(17964..18464)
                     /locus_tag="IRB70_003672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000528931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633535.1"
                     /translation="MGNYSDFETDFVQRTLALIDQYNEMIEVLGKPFREQYNYTLTLN
                     CLLGLIVLPKERALSFLLADRLTRQLKAEMGLHESQLPGPEMNLRELIHKMRNSVAHF
                     CVQVESASDAHLVDWIVFRESQKDGEVYASFSAPELLPFLKYYATLLLDNMARRRAPD
                     VNILDL"
     gene            18729..18959
                     /locus_tag="IRB70_003673"
     CDS             18729..18959
                     /locus_tag="IRB70_003673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBC0633536.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDRIILRPLR
                     PSWSSFLELEKADPGFMTEREDVVCDEGRFNL"
     gene            18956..19372
                     /locus_tag="IRB70_003674"
     CDS             18956..19372
                     /locus_tag="IRB70_003674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HBC0633537.1"
                     /translation="MNKIYMLDTNICSFIMREQPEAVLKNLEQAVLRGHRIVVSAITY
                     SEMRFGATGPKASPRHVQLVDAFCARLDAILPWDRAAVDATTEVKVALRLAGTPIGPN
                     DTAIAGHAIATGAILVTNNVREFERVPGLVLEDWAG"
     gene            complement(19417..>21299)
                     /locus_tag="IRB70_003675"
     CDS             complement(19417..>21299)
                     /locus_tag="IRB70_003675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pcar"
                     /protein_id="HBC0633538.1"
                     /translation="MPGSLSTEDNNFIRAVTSGRLPDETAKMPLSNIANTVAKLHGLG
                     ILMHDNAWHPQILWYLMRNDTNSLKTIMRMQAEVGAERRMVRLANEIFPLWEPAAQRE
                     YIRLMVDGDGHLSTMIHQIGRLNDTVAEQNLLPVLLSLPILSWEAVSQITREELQRLI
                     DLQFNLVTSLPENCAQFFCENLRNSGCRLTNIPLARSDSGQETLHLVVQKKLWTYSTL
                     NLQNICFSLSHESENNSDTFRKKPVALIKSLRIPNLEKYVYENISSFIRDVFIHSEEN
                     DLIPDFLNSTFVDWDDAKYMTESMSFVLEDVSVILNKENTETTEISYDQNLYSLLAHH
                     NHITPCWNNVISLLSEDASIAGDTFCEWLNINYSLLPNDSLPLTDVQFSQLLIKAVTS
                     PHISKEALIAITMAFRITLINVPENLPLNNAAVLIKQKWLAPTSTVFEQLYQALYEEG
                     DKLTSLLYALICARPVLLSDNYELVLFSDDQFDLGITRLILNGDKIADEVCISILNWL
                     WEKDEALLSEAPLLSQQALIRFSTKITDDRQKQALLMQCLKNDGGSHKFIRQVLMTFG
                     HQDYAAFLTERNYRSIPRSDAMWQLAVQLGNSGFIRPPKLTHADTRIRIEPFFNAENE
                     YD"
BASE COUNT         5200 a         5751 c         5351 g         4997 t
ORIGIN      
        1 aggaaaaaga agaacagtag cagtagcagt agcagtagca gtagcagtag caggaacaac
       61 aacatcagta acagacaaat gacaggcatg aagaaacaga agcccccatc agaacgtccg
      121 cgtaatgaaa ggggcggcgc gtgagcgcgg cccctttcag cgccaccggc gcgcgttttt
      181 tcccggcgcg ggcagacagg catttatcct cccgccggcc ctgtgtcatc aggcacgcag
      241 acgaataatc atcgtcggga catcggtata agcaaacgtg ccgcgcggca gctcctcgcg
      301 gacgtcagaa aacggtaaca gcttctcctg ctggcgtggt ccgttgagac agacggcgac
      361 cagcacgcca cccggacgca acagggaaaa ggcccgcagg atatgccgga tatcctgccc
      421 gtggctgaac ggcggattca tgataacccg gctgtaatac tgcaccggca gccattccat
      481 gaagtcgcca cactgaaccc tgacaccgtt aaaattttcc cgcagatacc ggaccagccc
      541 gctgttgatt tccaccgcat cacacatggc ccccggcgcg gtatcccgaa tcgcccgcag
      601 tatggccccg gtgccggcag agggttccag aatgtgatca cggttgctga tctccgccag
      661 catcaccagg cgatcacaga ccggggcagg agtcacaaaa agctgagatt cagcccggat
      721 ttcagcaacc ggcgcggcgt tatccagcct tgcgcgcatc agccggatac gttctcttaa
      781 ctgactgtgc atatcattat ctccgtcatc ccccggggat tttcccgggg ggatatacct
      841 tatttctgtg ggatttccgt gattttcatg tcggagatat acacattcac caggcggaaa
      901 ttattgtcca ttgtgcggcg gtaccggtat gccccgtggt cttctgcttc tgccacactg
      961 cgcacggcct tacagtcccg gggcagggcg gcccactgtg cctttgtcat ttcccggaaa
     1021 ccttcccccg gatagttgac taccggcgga cgcttcgcgg cctgactggc gacggcagcc
     1081 tcttctgccg atggtgcttt gtagtccgtg atgcgatcgg gcgtcacttt catcgtgccg
     1141 ctgtacccga gaaaactgta atttggcgtt gtgactgaac tcaccgcccc gttgcttttg
     1201 ttcacacgga tgatggtcag ccactcgccc cggctgaaaa cctgtccgcc cggctcaaaa
     1261 tcctgtgtcc gggtaaccac gccgccgctt tcgtccagca tggcacgctc atagatcagg
     1321 cggttctgat agtggttaac ccagcgttgt tgatgctgaa tctgccgttc atgacagcgg
     1381 atcgcaattt cgcgggcctg ctccgtggtg atgatgtcat catccagggc cgaccataac
     1441 gatcgacttc cttcatactg gcttttttct gccgggcgcg gatacgtatc cagcgggaaa
     1501 caggcgctga tatggtcatg actgctgatg agttttgcca tattcagatc cagcgattca
     1561 gcccgccaca tcgtcagata tttctgcgac tgcgcgatgg tcttttcagc cttgcgcaaa
     1621 tcagcttcga tttttttgat acgacgccag cgaacgtccg gacgttcttt atacttcgcg
     1681 tgaagcagtg ccgaccgcgc ccgctcttcc cagtattccg cacgttcaaa gagcatcacg
     1741 gctcgtttca tgccgttttc aatacgctgc gcatcacgac gggcgcggcg ttcgctgtga
     1801 tgccccacaa gaatgggctg accgggcggg atcatcgcgg ccagtctttc cacttcatca
     1861 agtgcctgtg cggattcact ggcccgcttt ccgctgtatc cggtaaaccg ctccgcccgt
     1921 gcttcctgac gttcagcgag cgtgctgtct tcatcctcaa tctctccggc aagtgagagg
     1981 agcacgtctt cccggcccgg tgtccaggct ggcgcgacaa acagcgcctg ttttggtgcc
     2041 cagcggaaac cggcatcatg cactttttta tacgtctccg ggtcaagacg tgacacggca
     2101 tacaggcgca gtttgttgtc atccggtgag taggtcgcgc ggtacatctg cacagggctg
     2161 gcggcttccg gggcggtcat ggtgattgct gctaatgtca taaaatgttc tccttccgtc
     2221 tgttgccgcc cctcgcgggg cggctcacct catcagttaa aagcgcgttt cagttcgagt
     2281 gtgcggagca cctgcccgaa ggccgtgttt ttcatggcgg ggatgtgtac accacgcccc
     2341 cggtgaaaac tccgggcaat gtgtcgcccg aaggctttca gcacggggtc aatttccggc
     2401 gcggggatgt cttcgcgtct gaaacgggga tgacggcggg gctttacagc cgctgcggaa
     2461 ggtgaaacaa tacttactgt cataatttag cctcttatga cgttaattaa tgaaaccgta
     2521 aagactgttc gtgcagtctc tgcggtgtgg attaagcagg tccctgacct gcttttttca
     2581 tatctgcgtc tgacgttctc cggtgttttc ctccttctgt tcctgcgttc tcattacctg
     2641 ccagccggat gactgacaga acacataaat gcgtattgcc ggagcctgaa ataaatcctg
     2701 atttttaaag aacatcaccc gttgagtttc gggagccgcg gttttgacgt ttcgcgggaa
     2761 cctgctgctg tataccctgt ggtatgaact tcacccgttt gagaaccttc gccgcaaggg
     2821 gcatcactgc cacggcctga cgcacctgtc ctgggcagaa cgcaaaattt tttaccgggt
     2881 tttgggtaaa aaattttgtg ggctgttcat ttaccctgga cagtcagtgc ggcaggttgt
     2941 ggctgtatca gccccaggcg acagggactc atacgggtgt gtggcaccgg caggcaatga
     3001 gcagggaccc gccgcaacga cggagagcgc gtgcgcgaaa cggcgttgcc ccttacatcc
     3061 cggcggcctt ttgccgggat gccgggagcg caggccacgg cgcgacaagg gtggcgcgac
     3121 cggaacggtc gctgcaagcc cggggttttc acgcatcgga ccgtagcgac agcccgaaac
     3181 cgcgccagcg ggttcggcgg agactggcgg gtgcgccagc agctgcctgt cggagtcggg
     3241 cctgacgacc ggatgccgcc aggcagccgg gagccgaagg tgcgcccggc agacagaaca
     3301 acactgcagt agtcagaatc agagcagcag ataaaggaac aacaacatca ggaacagttc
     3361 cataacataa gaaagaaaca ctcctgagtc agacacatca cagacgggaa gggtaacggg
     3421 cgacgcgcca gcgtggcccg cttcccttcc ggcaggcgtc agcctgccag gggttttcgc
     3481 gcggactgac aggcggcctc caccgcctgc ccctgtatca cctgtttctg ctaccctgta
     3541 agatgtagtg accgcccagg aaaaccgcct gctgattcgc cacaaaatcg cagatttcat
     3601 caacaatctg cgcggtggtg agcggtttct gccccatttc acgacgccgc gcattaatca
     3661 cggccctgta attacgcaga atttcgcggg tttctgtgct gatattcatg acatcgtctc
     3721 cccgtccagc gcctgtaaca caacgtccat tgcttcgcgt tcctccctga cgaatgcgtc
     3781 accgtcgccc ccgttctcac tcccgacggc atacaggcgc ttcatttcac tgcctgccag
     3841 cgccatcact ttttccagca tcaccgccgg gactgtcacc tgacggctgg cgcgcttttc
     3901 ttccatcagt tcacgaacaa cgccgtgaac aacgctgaca tccgcaccat attcaaaggc
     3961 atcgtccagc cgctgcatga cggtttccag ctcatcgtct gtcagactcc agtcctgggc
     4021 tatgtgacgc acatccccac gggtcagcac tacggcaaaa acgcattcac tgtccggcac
     4081 gtctgtatcc agcacttcgc ggataatttc tttaacagta cagtacatgt tctcgtctcc
     4141 tttacagggg cggcattgcc gccccgtccg ttaatcagtc cagagccgcg taaatcgcgt
     4201 tgcattcggg gtgaaattcg atgtgacgcc acaactgcgc atcgcgcatc cggtaaagct
     4261 gggtcagtcc tgcatccccg ctgtcgtggt acagccacaa ctggcggtta atcacaaggg
     4321 aggtcaggat gatgcctgcg gcatcagcac tcacggtacg gtcaaaccag tttgcaccgt
     4381 tcaccatgtg gaaacggtcg ccatccggca tcatgtaacc gccaccgtcc ggcaggcgga
     4441 tgaagtgcca gaagcctccc tgatattccg gcatcatttt ttgcgccagc gcgtacacat
     4501 acgcctcggc atacagaaaa tcgttgccaa acagatacgg cagaaaggag agacggtcgc
     4561 actcttcaac attcagagtg acaggtttcg catattgcat gatgttttcc tccgttgttc
     4621 acatattccg cgacaccggg cggtgccgtg cctccataaa agccgggcga acaggcgggg
     4681 atgcaggggc gcaagggaag ccgcagcctg acgcacacgg ctgacgggag ttgcagggtg
     4741 agaccgcgaa atctgagcgg gtgaacgacc ggaaaatcac ggcagacggg aaggagggac
     4801 cgggtgaccg cagcggcgaa gcgtaccctt gcatcaacgc cagcccggct aagatggagg
     4861 cacggcacag cccgcacacg acgctgaggc cacataactg aaaaaccaca aggccatgcc
     4921 ctgcatggcc gggtaaagcg gagccggcgg cgacttcctt tgtgctctgt ccggggaccg
     4981 gcaggaaaaa ggcggggatt taccccgcca gtgtcatcat ttccggattt ttgccagggc
     5041 atccgccatg ctgcggattt cggtccgggc ttcccggacc acctcccgca gaacaccacg
     5101 gtcaaaccag cggcggggcg gttcatccgg tatacgcagc acatcgcagg ccagcccact
     5161 ggacaggata tgctcaatac actcactgac cagatacatt tccaccgacg aaaaacgtgc
     5221 tccccggttc acgatggcat cgagcaccac gggcaggttt tcgtcatctt catcgagcca
     5281 gcaggggtga tcgctttcct tcacgaccag gcgaaagcgg cgcgtctggc gggtcagcaa
     5341 cgtctgaccg gtggtggtca gcgccgcacg gatacgccgc gcatcttctg ccacctggta
     5401 acagatgctt cgtaccgcat cgtgcaccgc atcaagaaca gccctgattt cgtcttcggt
     5461 cagccattct ccggcatacg ggaaagacac ctgcgttccg tctgccggaa gtaccggcag
     5521 cgactgccac tgactgccgg acagtaccag ttccgccccg gttccggtca gtctctgaat
     5581 ggcggaggcc aggagcggcg gcagtacgcc gccgtgacgg ttgataagta acgtcgccag
     5641 ccggggcgca tccagccgca cgtaaatgct gatccagccc ggatagttcg gatttcgctg
     5701 gtcaacatcc gtctcttccg gccagccctg cgccagcagc aggttacggg cgtgacgaca
     5761 aatcagtgcg ttcagcgtgc tgttttcgtt catgattaag cgttctccct gtatcgccgc
     5821 ccgcagggca ggcggcgata acatcagttg ttttcgtgtg tgttgttttt cagcagggtg
     5881 cgggcctgat taaccaccgc ctgacggcgg gtaacgcatt ccgggacggc gaggccgtta
     5941 tcacgggcgg cccactcacg tttccacagt gcctgttcag cggtctgaat cagggacgcc
     6001 agcagttcag cagggacggt cacctggcgg ttttcgctca cgttgctgat aatctccatc
     6061 accgcggcgg aagaaatacc ggattcagtc cgctggtctt ccgggatgtc ctccatgcgc
     6121 gccaggacgg tcctgatttc atgatcggtc agagaaattt ccataccgtc agccagtgcc
     6181 tgaatctctt ccggggacca gataaccagc atcagcggcg cgtctcccgg atactttgct
     6241 gccagctccc ggcatagcgt ttcgcatgtt ccgtacattc tcgtctcctt ctcaatcttt
     6301 gaagcaggaa tccagttcca gaatttcggt atacgcctcc ataaacaggc gattggcgcg
     6361 atacagcgtc tggcgtgtca ggcgttcaac aagcacatcg gaatcaaagc gacagcgatg
     6421 ctccatatcg ttcagcctgg cccgaaggtc acacatggtg ttggccacct ccgccacgtc
     6481 ggcgcgaagt ttttcgtgtc cggcatagtt catttacgca gcctccggca taaaccagtc
     6541 atcattcgcg gccccctgct gcatggcccg ttgcacggcg gcaaggcgtt gctgcccggc
     6601 acggtgatac tgctcaagca gctcgatacc gatataccgg cgtccggact ggagggcggc
     6661 gacgcaggtt gagccgctgc ctgcaaacgg gtccagcaca attgcgttcg ggtgtgtgaa
     6721 gctctcaatc agcggttgca ggctggtaac gggcttttcc gtcgggtgat gacgattgcc
     6781 agaatatttc cagcccagca cgtccggcag cgggttttgt ggcagacgtg gacggccttt
     6841 tgccaggatg taggcgcatt cgtggcgata gcccacatat gcggccttcg atgtgtagtt
     6901 tttggtgaag accaggtgac caacaacgct gaatcccgca tttttccagg cggccataaa
     6961 gcgatcgacg cggttccagc cgtagaagct caccatcagc gcgtcttttt tgagtacgcg
     7021 gtacatttca ttacaggccg gttgcagcca ttcatcggtt ttatcgccgg cgatggtgcg
     7081 cccggaacgg tcacgaaaac cgacgagata tggcgggtca gttaatatga aatcaatggc
     7141 gttatcaggg atacgcgtca taacatcgat gcagttacca aggacaaaac gggacataac
     7201 aacgctcctt ctcttacaga gggcaccggg agggcccccc tgtggtgccc gttccccgct
     7261 gcctgtgggc tgttcaccgc gtccggtaac gggtcaggcc gaccgtggaa tatcgcagcc
     7321 gtcgtctttt tgacggcgag aatatgccgc gaaagcggct tgaagggcgt tcatcagaaa
     7381 agggcgacag gctggcgtac actgtcaccg gtgccagccg ggagcagtaa aagcgcccgt
     7441 cccgtgcccg ccggacgcgg gacactgacc acaggcagcg ttcctgccgc gccgcgtcag
     7501 ccggcgcagt aaaaagagga gcacggcgac atcctttgtc ggaaaagaaa cgggcggttg
     7561 cccgcccgtc tccgtcatac ttcatccccc gtaatgcgcc accttgtcga ctatccactc
     7621 cggcgcggtg acttccggca gctcatcatc atctgtcggg gaagaccatt ccagttcccc
     7681 ccacagcaca tcaacaagct ctccacgctc atatcgctgc cagccacaga aattgcagcc
     7741 ctgttcggcg taccagtgct ccagcgtgca gccgaaacgg cggcttaatt ctgcaacaac
     7801 gttgctttcc ggctgacacc acggcgtgtc gaaatccact tgaatgaagt tttctccctg
     7861 acggctgata ttcacctcat accccacagg ccacttcacg ccatactgtt ccgtatacca
     7921 gtgatacgca gaaggaacac cgttcagaac accaccgtta aagccattca cttcaacatc
     7981 caggcgggtg ggcagaaccg tcagcaggtc aaacggcatg gttttttccg gcagtacatt
     8041 gtcacacaga cggttccacc acaccgatac atcctcgtta ctccagaagc cacaccagtc
     8101 acctcttttt gcggtgaaat gcacggtgat ggtttccctg acctcatccg gtaatccttc
     8161 ccagcgacgc tggccagtac cactctgcag ccagagttca tgcagcatca ggcagttttg
     8221 ctcatccagc agtacaccgt tctgcaggtg tgtcagccag cgggtgaacg cgatattctc
     8281 cggcgataca acaccacgtc cggcatccgt cagtccgggg cacggttcaa actgcacatc
     8341 ttcagtggtc tgcagaagtc cggcacttcc ggccagaaac agctgaatac cttcatttgt
     8401 ggcgcggcga taaagcggtg tgacggcacc gctggccagt cgtttaatct cagcaatctg
     8461 tgccggttca ccagaaaaat gcatacgatt cgagcaccag tttggcatgg gaattctcct
     8521 ctcacatgcg gcctccatca ggccgtgccg cacctgtaac cgggcgaccg catacgaatg
     8581 caggtgcggc cccgaagccg cagcgcgtgg aggaggaacg acgaaacgtg accgggtgag
     8641 gaggccggcg acagcgacac acttgcatcg gatgcagccc ggttaacgtg ccggcacggc
     8701 ctgggtaacc aggtattttg tccacataac cgtgcgcaaa atgttgtgga taagcaggac
     8761 acagcagcaa tccacagcag gcatacaacc gcacaccgag gttactccgt tctacaggtt
     8821 acgacgacat gtcaatactt gcccttgaca ggcattgatg gaatcgtagt ctcacgctga
     8881 tagtctgatc gacaatacaa gtgggaccgt ggtcccagac cgataatcag accgacaaca
     8941 cgagtgggat cgtggtccca gactaataat cagaccgacg atacgagtgg gaccgtggtc
     9001 ccagactaat aatcagaccg acgatacgag tgggaccgtg gtcccagtct gattatcaga
     9061 ccgacgatac aagtggaaca gtgggcccag agagaatatt caggccagtt atgctttctg
     9121 gcctgtaaca aaggacatta agtaaagaca gataaacgta gactaaaacg tggtcgcatc
     9181 agggtgctgg cttttcaagt tccttaagaa tggcctcaat tttctctata cactcagttg
     9241 gaacacgaga cctgtccagg ttaagcacca ttttatcgcc cttatacaat actgtcgctc
     9301 caggagcaaa ctgatgtcgt gagcttaaac tagttcttga tgcagatgac gttttaagca
     9361 cagaagttaa aagagtgata acttcttcag cttcaaatat caccccagct tttttctgct
     9421 catgaaggtt agatgcctgc tgcttaagta attcctcttt atctgtaaag gctttttgaa
     9481 gtgcatcacc tgaccgggca gatagttcac cggggtgaga aaaaagagca acaactgatt
     9541 taggcaattt ggctgtgttg atacagcggg taataatctt acgtgaaata ttttccgcat
     9601 cagccagcgc agaaatattt ccagcaaatt cattctgcaa tcggcttgca taacgctgac
     9661 cacgttcata agcacttgtt gggcgataat cgttacccaa tctggataat gcagccatct
     9721 gctcatcatc cagctcgcca accagaacac gataatcact ttcggtaagt gcagcagctt
     9781 tacgacggcg actcccatcg gcaatttcta tgacaccaga tactcttcga ccgaacgccg
     9841 gtgtctgttg accagtcagt agaaaagaag ggatgagatc atccagtgag tcctcagtaa
     9901 gcagctcctg gtcacgttca ttacctgacc atacccgaga ggtcttctca acactatcac
     9961 cccggagcac ttcaagagta aacttcacat cccgaccaca tacaggcaaa gtaatggcat
    10021 taccgcgagc cattactcct acgcgcgcaa ttaacgaatc caccatcggg gcagctggtg
    10081 tcgataacga agtatctcca accggttgag tattgagcgt atgttttgga ataacaggcg
    10141 cacgcttcat tatctaatct cccagcgtgg tttaatcaga cgatcgaaaa tttcattgca
    10201 gacaggttcc caaatagaaa gagcatttct ccaggcacca gttgaagagc gttgatcaat
    10261 ggcctgttca aaaacagttc tcatccggat ctgaccttta ccaacttcat ccgtttcacg
    10321 tacaacattt tttagaacca tgcttcccca ggcatcccga atttgctcct ccatccacgg
    10381 ggactgagag ccattactat tgctgtattt ggtaagcaaa atacgtacat caggctcgaa
    10441 ccctttaaga tcaacgttct tgagcagatc acgaagcata tcgaaaaact gcagtgcgga
    10501 ggtgtagtca aacaactcag caggcgtggg aacaatcagc acatcagcag cacatacgac
    10561 attaatcgtg ccgataccca ggttaggcgc gctgtcaata actatgacat catagtcatg
    10621 agcaacagtt tcaatggcca gtcggagcat caggtgtgga tcggtgggca gtttaccttc
    10681 atcaaatttg cccattaact cagtttcaat acggtgcaga gccagacagg aaggaataat
    10741 gtcaagccca ggccagcaag tgggctttat tgcataagtg acatcgtcct tttccccaag
    10801 atagaaaggc aggagagtgt cttctgcatg aatatgaaga tctggtaccc atccgtgata
    10861 cattgaggct gttccctggg ggtcgttacc ttccacgagc aaaacacgta gccccttcag
    10921 agccagatcc tgagcaagat gaacagaaac tgaggttttg taaacgccac ctttatgggc
    10981 agcaaccccg atcaccggtg gaaatacgtc ttcagcacgt cgcaatcgcg taccaaacac
    11041 atcacgcata tgattaattt gttcaattgt ataaccaaca cgttgctcaa cccgtcctcg
    11101 aatttccata tccgggtgcg gtagtcgccc tgctttctcg gcatctctga tagcctgaga
    11161 agaaacccca actaaatccg ctgcttcacc tattctccag cgccgggtta ttttcctcgc
    11221 ttccgggctg tcatcattaa actgtgcaat ggcgatagcc ttcgtcattt catgaccagc
    11281 gtttatgcac tggttaagtg tttccatgag tttcattctg aacatccttt aatcattgct
    11341 ttgcgttttt ttattaaatc ttgcaattta ctgcaaagca acaacaaaat cgcaaagtca
    11401 tcaaaaaacc gcaaagttgt ttaaaataag agcaacacta caaaaggaga taagaagagc
    11461 acatacctca gtcacttatt atcactagcg ctcgccgcag ccgtgtaacc gagcatagcg
    11521 agcgaactgg cgaggaagca aagaagaact gttctgtcag atagctctta cgctcagcgc
    11581 aagaagaaat atccaccgtg ggaaaaactc caggtagagg tacacacgcg gatagccaat
    11641 tcagagtaat aaactgtgat aatcaaccct catcaatgat gacgaactaa cccccgatat
    11701 caggtcacat gacgaaggga aagagaagga aatcaactgt gacaaactgc cctcaaattt
    11761 ggcttcctta aaaattacag ttcaaaaagt atgagaaaat ccatgcaggc tgaaggaaac
    11821 agcaaaactg tgacaaatta ccctcagtag gtcagaacaa atgtgacgaa ccaccctcaa
    11881 atctgtgaca gataaccctc agactatcct gtcgtcatgg aagtgatatc gcggaaggaa
    11941 aatacgatat gagtcgtctg gcggcctttc tttttctcaa tgtatgagag gcgcattgga
    12001 gttctgctgt tgatctcatt aacacagacc tgcaggaagc ggcggcggaa gtcaggcata
    12061 cgctggtaac tttgaggcag ctggtaacgc tctatgatcc agtcgatttt cagagagacg
    12121 atgcctgagc catccggctt acgatactga cacagggatt cgtataaacg catggcatac
    12181 ggattggtga tttcttttgt ttcactaagc cgaaactgca taaaccggtt ctgtaacccg
    12241 ataaagaagg gaatgagata tgggttgata tgtacactgt aaagccctct ggatggactg
    12301 tgcgcacgtt tgataaacca gggaaaagat tcatagcctt tttcatcgcc ggcatcctct
    12361 tcagggcgat aaaaaaccac ttccttcccc gcgaaactct tcaatgcctg ccgtatatcc
    12421 ttactggctt ccgcagaggt caatccgaat atttcagcat atttagcaac atggatctcg
    12481 cagataccgt catgttcctg tagggtgcca tcagattttc tgatctggtc aacgaacaga
    12541 tacagcatac gtttttgatc ccgggagaga ctatatgccg cctcagtgag gtcgtttgac
    12601 tggacgattc gcgggctatt tttacgtttc ttgtgattga taaccgctgt ttccgccatg
    12661 acagatccat gtgaagtgtg acaagttttt agattgtcac actaaataaa aaagagtcaa
    12721 taagcaggga taactttgtg aaaaaacagc ttcttctgag ggcaatctgt cacagggtta
    12781 agggcaattt gtcacagaca ggactgtcat ttgagggtaa tttgtcacac tgaaagggca
    12841 atttgtcaca acaccttctc tagaaccagc atggataaag gcctacaagg cgctctaaaa
    12901 aagaagatct aaaaactata aaaaaaataa ttataaaaat atccccgtgg ataagtggat
    12961 aaccccaagg gaagtttttt caggcatcgt gtgtaagcag aatatataag tgctgttccc
    13021 tggtgcttcc tcgctcactc gagggcttcg ccctgtcgct cgactgcggc gagcactact
    13081 ggctgtaaaa ggacagacca catcatggtg ctgtgttcat taggttgttc tgtccattgc
    13141 tgacataatc cgctccactt caacgtaaca ccgcacgaag atttctattg ttcctgaagg
    13201 catattcaaa tcgttttcgt taccgcttgc aggcatcatg acagaacact acttcctata
    13261 aacgctacac aggctcctga gattaataat gcggatctct acgataatgg gagattttcc
    13321 cgactgtttc gttcgcttct cagtggataa cagccagctt ctctgtttaa cagacaaaaa
    13381 cagcatatcc actcagttcc acatttccat ataaaggcca aggcatttat tctcaggata
    13441 attgtttcag catcgcaacc gcatcagact ccggcatcgc aaactgcacc cggtgccggg
    13501 cagccacatc cagcgcaaaa accttcgtgt agacttccgt tgaactgatg gacttatgtc
    13561 ccatcaggct ttgcagaact ttcagcggta taccggcata cagcatgtgc atcgcatagg
    13621 aatggcggaa cgtatgtggt gtgaccggaa cagagaacgt cacaccgtca gcagcagcgg
    13681 cggcaaccgc ctccccaatc caggtcctga ccgttctgtc cgtcacttcc cagatccgcg
    13741 ctttctctgt ccttcctgtg cgacggttac gccgctccat gggtattttc agtgttgcca
    13801 ccatcgtctg cagctggctg acgtaccagg agtcagagag cggaaccagc cggtgagtct
    13861 gctgaccggc gggcattctc cccgccgtcc tggcagcttt ttcggtccgt tgtttcaggg
    13921 tcgcaagctg cacaaacgga tacggaggcg caagcgaaaa atccccccgc gtcagcgcca
    13981 gtgcttcatt aatgcgtgct ccggtgttcc acagtgtggc cagcagcatc ttgcggtgca
    14041 gatccgggac gtaatggagc agggcactca cttccggagc cagcagatat tttggcagtt
    14101 catcatggac catcgacatc tggcgaagtg ccagagctgc cggataatca atggcaacag
    14161 gcagcgatgc aggctgcccg gcagaataca ctgccggtac catgactgca gactggctgt
    14221 gtataacgga gcctgacatt tatattcccc agaacatcag gttaatggcg tttttgatgt
    14281 cattttcgcg gtggctgaga tcagccactt cttccccgat aacggagacc ggcacactgg
    14341 ccatatcggt ggtcatcatg cgccagcttt catccccgat atgcaccacc gggtaaagtt
    14401 cacgggagac tttatctgac agcagacgtg cactggccag ggggatcacc atccgtcgcc
    14461 cgggcgtgtc aataatatca ctctgtacat ccacaaacag acgataacgg ctctctcttt
    14521 tataggtgta aaccttaaac tgcatttcac cagtccctgt tctcgtcagc aaaagagccg
    14581 ttcatttcaa taaaccgggc gacctcagcc atcccttcct gattttccgc tttccagcgt
    14641 tcggcacgca gacgacgggc ttcattctgc atggttgtgc ttaccagacc ggagatattg
    14701 acatcatatg ccttgagcaa ctgatagctg tcgctgtcaa ctgtcactgt aatacgctgc
    14761 ttcatagcac acctcttttt gacatacttc gggtatacat atcagtatat attcttatgc
    14821 cgcaaaaatc agcgcgcaaa tacgcatact gctatctggc ttttagtaag ccttatgtat
    14881 tttacctttc gttatgttaa ccaataaaaa ttaaaatctg acttataaaa acaaagcgta
    14941 attaccgcat tcccgtttcg tatggatccg actttatttg aataaacgac tttccggaag
    15001 tgtacaacgc tgagaaaatc atcatatcgc tgttttccgc ccctgcgcgg cgcatcacag
    15061 tccagagata caacacaaca tatagtgcca tgggcaactg tatgaggcac tacatgctgt
    15121 gctgacggga tgtaacgctg tgcggaggga gaggaagatc cgtaacttgg ggttttcgga
    15181 tctcagtgga gaaaactgaa agaaaacaaa aactcacaca taaattaaaa tgtcaacaca
    15241 aaaaacaacg aatagcactt tttgcattct cgcatagcac taattgctaa aacggagtat
    15301 atttgcgtca tcggctgctt caggtggcct catgaccatc tttaaggaga atattgtgga
    15361 cacaagtctg attggaccga tccttacggc gctgcttgcc gctgcggggt tctactgtaa
    15421 gttttggttt acgcgttatc aggcctcccg tgatcaggcc cagaaagtca gccgggcgat
    15481 cgaggatgtc ctgagcaaaa tggccgcgct gttcggacag aagaaacctg cccggatact
    15541 gagagaggaa ttttccgctg ttattgcgcc gcttcatcag gaaatgcgta tccttgacga
    15601 tatgacgtcc cgtctgccgc tgaaatggct gcagcgcgaa cagcgccacg ttctttatca
    15661 tgcccgatgg ctgcagcggt atctggattc gcgcaggggc ggcagtgacg gggacttttt
    15721 cctgctattg cacgatgtgg cgatggggac cgattatcag gttgctgaca ttctggcatc
    15781 gcagcatgac tgtaagcagc gtcgtggatc acagctgccg gttaacctga aaacctgccc
    15841 ctaagagggg gcagttgaaa gcagataata tccggcatca gtcgggtgat cccgacacca
    15901 catatggcat gcgtctggct tcatcaaagt cccgcagctc ctgcgccagc ctcatgatct
    15961 ctgcgcttgg taccgggagt ttacccagga gttccttaaa tcgactggca accgactgga
    16021 ttgacacgct gttggtcctg gctgttttca gattggtata aacaaggcgg gaaagtggct
    16081 ttgtcagcgc cttgtcttcc atgaatcgct tgaatgtcca gagataaata tctaccaact
    16141 ccagacctgc actcttggta ccggactgga atacaagtgg ttcagccggc atatttttca
    16201 tgttcataac aggtaatccg ggccccagtt cccagggcat atcccgtatc tggtagtaaa
    16261 actcgttaag ttcacgctgg gtggtgttga actgtgactg ctggtcaaca atgatactgg
    16321 cctttctttc tggtgccccc agtcgggaac agatcccgtg caatacggac tgaaagccaa
    16381 tcatattggg cataatccgc agcctttcct tgttggtttt acagttatag cccaactgtt
    16441 caaaattggc tgacgcccag ttcagggcat cggtgatcag ctgcttcgac cggtggtcca
    16501 gcgcgctggc tgccgtcctg ctgatcagtt catcactgac ggtacaaaaa agttccgacg
    16561 cacgctcatc atgcgcctcc agccttgccg tccatgcgtt tgaagcaagt tcatcatcaa
    16621 acaggctggc cagattcagc agcagggggt agcgcagagg ggtccagtat gcagaccagg
    16681 gtacggctgg attcattccc tgatcaaata cctggtcgaa gaacgaaata atggcatgat
    16741 cgcgctttac tacctgccag atgtcaaacc gtatccggtg ctttttctgc agaaccagca
    16801 gcgtatctac aaggtcagaa aggcggtgca agcccagttc cgcagcgtgc aggcgctgca
    16861 cgccaagcgt tttgcgtatt acggctagat ccgcttcagc aaccttatcc agattagcat
    16921 cagacgacag cactccgtag gagaggactg gctgggtttt gtcaaaaagg tttcggccag
    16981 tctggcctgt ttcatccaca taaaagtgca ttcagagatc ctttaccagg caggaggaag
    17041 ggaaacggca taatccgggt caatgtaaaa cctttctgca gccagctgca agtgatccac
    17101 ttaaggcttt aatgacctca atactgggtt cacggcaatg aacaaacggg ccggatcaca
    17161 gacccgtttt ttagggatta catctgcccg ggctgcagaa actcgattct ggcaatggcc
    17221 gacctagaca cagatttccc gtcacagtct atgccgaaag ttgcgtttcc gtccggcggg
    17281 aggtcacgga ctgatgtata ggcatatgac agagccgttt caagaactcc tttttcataa
    17341 acaatatccg cctcgaacca gacaatacag ggatgaagca cgctcagata atgcggttta
    17401 agatcgtggc cgtatttctt ctggtaggcc ttacagacat cctctaccag ctccggcagc
    17461 cagaggtaat catgcagtcc attttcactg gcgttaaaat gtaattcccg gactaaatgg
    17521 ccaaaaggcc cccagtggat tttatcgccg gttctgagct gaaacatctc atccggaacg
    17581 ccccccggaa catcccattc cttcaggtgt gtacggacca tctcattcgg ggccaggtca
    17641 agcagcattt tcatggcgag ggattctgac tgatttagcg ccagtaaccc cgccggaaaa
    17701 gtattaccgg cgaaagtccg ggtgccatga aaccacagag cccgggtgaa tggtcccggt
    17761 tcgcccagtt ccgcacagac gtattctctc agatactgag gtgcatcaac caactggcga
    17821 ggattaagct cgtagatact ttcaagatcg agcgaaagca gcactttttt cagcttttca
    17881 ggggaacagc caaacccggc agataatgta tgcaacgcct gagttcgtga ggagcaatcg
    17941 agaatcaaca tggtgtaaat cccttacaaa tccaatatgt taacatcggg ggctcgacgg
    18001 cgggccatat tgtcgagcag cagggtcgca taatatttca gaaagggtaa aagctccgga
    18061 gcgctgaagc tggcgtagac ttctccatct ttctgagatt ccctgaaaac aatccagtct
    18121 acaaggtgtg catcgctggc tgactctacc tggacgcaga aatgagcaac tgaattccgc
    18181 atcttatgga tcaactcccg caggttcatt tccggtccgg gcagctgtga ctcatgtaat
    18241 cccatttcag ctttaagttg ccgcgttaaa cggtcggcaa gcaggaaaga gagcgctctc
    18301 tctttcggta acacgataag acccaggagg caattcaggg tcaacgtgta gttgtactgc
    18361 tccctgaatg gtttgcccag cacctcaatc atttcgttat attgatcgat aagcgccagt
    18421 gttcgctgaa caaaatcggt ctcaaaatct gaataatttc ccatttaacc ctcccgttcc
    18481 ggttcgagaa tccactatat catccggcca gcctgacggc tcaggtacgg catttcctac
    18541 tatgatattt ttcggatccc ggtgaaaaaa gagagaaaca tgcagatacc atgcatatcc
    18601 atatgtttgg catctgcata tgacaggcat acgcatatct cacacatctg catatttata
    18661 acatatacat atgtatcaca tctgcatata ctaaacatat ataaaagccg ccttgccagg
    18721 aggaagacat gagaaccgta tctattttca aaaatggcaa taaccgcgcg atccgtctgc
    18781 cccgcgatct ggattttgag ggggtgagtg agctggagat tgtacgggaa ggggacagaa
    18841 tcattctgcg tcccctccgc ccgagctgga gctcattcct ggagctagaa aaggccgatc
    18901 cgggctttat gacggaacgc gaggacgttg tctgcgacga aggacgattt aacctgtgaa
    18961 caagatctat atgctcgaca cgaacatctg ctcgttcatc atgcgcgagc agcctgaagc
    19021 agtgcttaag aatctggagc aggcggtgct gcgcggtcac cgtatcgtgg tctcggccat
    19081 cacctactcc gagatgcgct tcggcgccac cggtccaaag gcatcgccac gccacgtgca
    19141 gctggttgac gcgttctgcg cccgtctcga tgccatcctg ccctgggatc gcgctgcggt
    19201 ggatgcaacc acggaggtta aggtggcgct gcgcctcgcc ggcacgccga tcggtccaaa
    19261 cgacacggcg atcgccgggc acgccatcgc caccggggca atactggtga cgaataatgt
    19321 gagagagttt gagcgggtgc ctggactggt actggaagac tgggcaggat aaaggagtaa
    19381 ggccgccccc gacggactta ccactatttt gcgatgtcag tcgtattcat tttcagcgtt
    19441 aaaaaagggc tctatacgaa tacgtgtatc agcgtgagta agtttcggcg gcctgataaa
    19501 tccactattt cccagctgga cagccagttg ccacatggca tcactacggg gaatgctacg
    19561 ataattcctc tctgtgagga aagcggcata atcctgatgc ccgaacgtca tgagcacctg
    19621 tctgatgaac ttgtgtgacc caccgtcatt tttaagacat tgcatcagca gtgcctgctt
    19681 ctgccggtca tcggttattt tggtggagaa ccttatcagg gcttgctggc tgagaagtgg
    19741 tgcctcagag agcagggctt catctttttc ccagagccag ttcaggatac tgatacagac
    19801 ttcatctgca atcttatcgc cattcagaat taaacgagta atccccaggt caaactggtc
    19861 atcagaaaat aaaacaagct cgtaattatc actcaataat acaggacggg cacaaataag
    19921 tgcataaagt agtgatgtca gtttgtcacc ttcttcgtac agtgcctgat aaagttgttc
    19981 aaacacagta ctggttggtg ccagccattt ttgcttgatt agtaccgcag cattattcag
    20041 tggtaagttt tctggcacat taataagagt tatcctaaat gccatggtta tcgctattaa
    20101 cgcttcttta ctgatatgag gtgatgtaac agccttaata agtaattgcg agaactgaac
    20161 atcagtcaaa ggcaacgagt catttggcaa taaagaataa ttaatattaa gccactcaca
    20221 aaaagtatca ccagcaattg acgcatcttc actcagtaga gaaataacat tattccagca
    20281 aggggtaata tgattatgat gagccagaag tgaatacagg ttttgatcat aagaaatttc
    20341 tgttgtttcg gtattctctt tgttcaggat aactgatacg tcttccagta cgaagctcat
    20401 actttctgtc atgtactttg catcatccca gtcaacgaat gtcgaattaa gaaaatcagg
    20461 aatgagatca ttttcttcag agtgtataaa aacatcacga atgaatgatg atatgttttc
    20521 ataaacatat ttttcaaggt tcggaatacg aagcgatttt attaaagcaa caggcttctt
    20581 acggaaggta tcactgttat tctctgactc atgagaaagt gagaaacaaa tgttttgcag
    20641 gtttaacgtg gaataggtcc acaatttttt ctgtaccacc aaatgcaatg tttcctgccc
    20701 agagtcactc cgggccaaag gaatgttagt caggcgacaa cctgaattcc gcaggttttc
    20761 acagaaaaac tgcgcacaat tctccggtaa ggacgttacg agattaaatt gcaaatcgat
    20821 gagtctctgc agttcttccc gagttatctg agagacggct tcccaagaaa gtatcggtaa
    20881 ggacagtaat accgggagaa gattttgttc agctacggta tcattcaggc gcccaatctg
    20941 gtggatcata gtggataaat gaccatcccc gtcgaccatt aatctgatat attcccgctg
    21001 cgcagcaggt tcccataggg ggaagatctc attggccagt cttaccatcc gccgttcggc
    21061 tccgacctct gcctgcatcc tcatgatagt cttcagagag ttcgtatcat tgcgcatgag
    21121 gtaccagaga atctgaggat gccatgcatt gtcatgcatc agtatgccca gtccatgcaa
    21181 ttttgctact gtgttagcaa tattgctgag gggcattttt gccgtttcat caggtaatct
    21241 tcctgacgtc acagccctga taaagttatt gtcttccgtg ctcagactac ctggcataa
//
LOCUS       DADXDL010000086        21263 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.086, whole genome shotgun sequence.
ACCESSION   DADXDL010000086 DADXDL010000000
VERSION     DADXDL010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21263
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.086"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1293)
                     /gene="eno"
                     /locus_tag="IRB70_003676"
     CDS             complement(<1..1293)
                     /gene="eno"
                     /locus_tag="IRB70_003676"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBC0633539.1"
                     /translation="MSKIVKIIGREIIDSRGNPTVEAEVHLEGGFVGMAAAPSGASTG
                     SREALELRDGDKSRFLGKGVTKAVAAVNGPIAQALIGKDAKDQAGIDKIMIDLDGTEN
                     KSKFGANAILAVSLANAKAAAAAKGMPLYEHIAELNGTPGKYSMPVPMMNIINGGEHA
                     DNNVDIQEFMIQPVGAKTVKEAIRMGSEVFHHLAKVLKAKGMNTAVGDEGGYAPNLGS
                     NAEALAVIAEAVKAAGYELGKDITLAMDCAASEFYKDGKYVLAGEGNKAFTSEEFTHF
                     LEELTKQYPIVSIEDGLDESDWDGFAYQTKVLGDKIQLVGDDLFVTNTKILKEGIEKG
                     IANSILIKFNQIGSLTETLAAIKMAKDAGYTAVISHRSGETEDATIADLAVGTAAGQI
                     KTGSMSRSDRVAKYNQLIRIEEALGEKAPYNGRKEIKGQ"
     gene            complement(1380..3017)
                     /gene="pyrG"
                     /locus_tag="IRB70_003677"
     CDS             complement(1380..3017)
                     /gene="pyrG"
                     /locus_tag="IRB70_003677"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase (glutamine hydrolyzing)"
                     /protein_id="HBC0633540.1"
                     /translation="MTTNYIFVTGGVVSSLGKGIAAASLAAILEARGLNVTIMKLDPY
                     INVDPGTMSPIQHGEVFVTEDGAETDLDLGHYERFIRTKMSRRNNFTTGRIYSDVLRK
                     ERRGDYLGATVQVIPHITNAIKERVLEGGEGHDVVLVEIGGTVGDIESLPFLEAIRQM
                     AVEIGREHTLFMHLTLVPYMAASGEVKTKPTQHSVKELLSIGIQPDILICRSDRAVPA
                     NERAKIALFCNVPEKAVISLKDVDSIYKIPGLLKSQGLDDYICKRFSLNCPEANLSEW
                     EQVIFEEANPVSEVTIGMVGKYIELPDAYKSVIEALKHGGLKNRVSVNIKLIDSQDVE
                     TRGVEILKGLDAILVPGGFGYRGVEGMITTARFARENNIPYLGICLGMQVALIDYARH
                     VANMENANSTEFVPDCKYPVVALITEWRDENGNVEVRSEKSDLGGTMRLGAQQCQLVD
                     DSLVRQLYNAPTIVERHRHRYEVNNMLLKQIEDAGLRVAGRSGDDQLVEIIEVPNHPW
                     FVACQFHPEFTSTPRDGHPLFAGFVKAASEFQKRQAK"
     gene            complement(3245..4036)
                     /gene="mazG"
                     /locus_tag="IRB70_003678"
     CDS             complement(3245..4036)
                     /gene="mazG"
                     /locus_tag="IRB70_003678"
                     /EC_number="3.6.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside triphosphate pyrophosphohydrolase"
                     /protein_id="HBC0633541.1"
                     /translation="MNQIDRLLTIMQRLRDPENGCPWDKEQTFATIAPYTLEETYEVL
                     DAIAREDFDDLRGELGDLLFQVVFYAQMAQEEGRFDFNDICAAISDKLERRHPHVFAD
                     SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWT
                     TLGPVVDKVYEEIDEVMYEAQQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQK
                     ANEKFERRFREVERIVAARGLEMTGVDLETMEEVWQQVKRQEIDL"
     gene            complement(4108..4443)
                     /gene="mazF"
                     /locus_tag="IRB70_003679"
     CDS             complement(4108..4443)
                     /gene="mazF"
                     /locus_tag="IRB70_003679"
                     /EC_number="3.1.27.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endoribonuclease MazF"
                     /protein_id="HBC0633542.1"
                     /translation="MVSRYVPDTGDLIWVDFDPTKGSEQAGHRPAVVLSPFMYNNKTG
                     MCLCVPCTTQSKGYPFEVVLSGQERDGVALADQVKSIAWRARGATKKGTVAPEELQLI
                     KAKINVLIG"
     gene            complement(4443..4691)
                     /gene="mazE"
                     /locus_tag="IRB70_003680"
     CDS             complement(4443..4691)
                     /gene="mazE"
                     /locus_tag="IRB70_003680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin MazE"
                     /protein_id="HBC0633543.1"
                     /translation="MIHSSVKRWGNSPAVRIPATLMQALNLNIDDEVKIDLVDGKLII
                     EPVRKEPVFTLAELVNDITPENLHENIDWGEPKDKEVW"
     gene            complement(4769..7003)
                     /locus_tag="IRB70_003681"
     CDS             complement(4769..7003)
                     /locus_tag="IRB70_003681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase"
                     /protein_id="HBC0633544.1"
                     /translation="MVAVRSAHINKAGEFDPEKWIASLGITSQKSCECLAETWAYCLQ
                     QTQGHPDASLLLWRGVEMVEILSTLSMDIDTLRAALLFPLADANVVSEDVLRESVGKS
                     VVNLIHGVRDMAAIRQLKATHTDSVSSEQVDNVRRMLLAMVDDFRCVVIKLAERIAHL
                     REVKDAPEDERVLAAKECTNIYAPLANRLGIGQLKWELEDYCFRYLHPTEYKRIAKLL
                     HERRLDREHYIEEFVGHLRAEMKAEGVKAEVYGRPKHIYSIWRKMQKKNLAFDELFDV
                     RAVRIVAERLQDCYAALGIVHTHYRHLPDEFDDYVANPKPNGYQSIHTVVLGPGGKTV
                     EIQIRTKQMHEDAELGVAAHWKYKEGAAAGGARSGHEDRIAWLRKLIAWQEEMADSGE
                     MLDEVRSQVFDDRVYVFTPKGDVVDLPAGSTPLDFAYHIHSDVGHRCIGAKIGGRIVP
                     FTYQLQMGDQIEIITQKQPNPSRDWLNPNLGYVTTSRGRSKIHAWFRKQDRDKNILAG
                     RQILDDELEHLGISLKEAEKHLLPRYNFNDVDELLAAIGGGDIRLNQMVNFLQSQFNK
                     PSAEEQDAAALKQLQQKSYTPQNRSKDNGRVVVEGVGNLMHHIARCCQPIPGDEIVGF
                     ITQGRGISVHRADCEQLAELRSHAPERIVDAVWGESYSAGYSLVVRVVANDRSGLLRD
                     ITTILANEKVNVLGVASRSDTKQQLATIDMTIEIYNLQVLGRVLGKLNQVPDVIDARR
                     LHGS"
     gene            complement(7051..8352)
                     /gene="rlmD"
                     /locus_tag="IRB70_003682"
     CDS             complement(7051..8352)
                     /gene="rlmD"
                     /locus_tag="IRB70_003682"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBC0633545.1"
                     /translation="MAQFYSAKRRTTTRQIITVSVNDLDSFGQGVARHNGKTLFIPGL
                     LPQENAEVTVTEDKKQYARAKVVRRLSDSPERETPRCPHFGVCGGCQQQHASVDLQQR
                     SKSAALARLMKHEVSEVIADVPWGYRRRARLSLNYLPKTQQLQMGFRKAGSSDIVDVK
                     QCPILVPQLEALLPKVRACLGSLQAMRHLGHVELVQATSGTLMILRHTAPLSSADREK
                     LECFSHSEGLDLYLAPDSEILETVSGEMPWYDSNGLRLTFSPRDFIQVNAGVNQKMVA
                     RALEWLDVQPEDRVLDLFCGMGNFTLPLATQAASVVGVEGVPALVEKGQQNARLNGLH
                     NVTFYHENLEEDVTKQPWAKNGFDKVLLDPARAGAAGVMQQIIKLEPIRIVYVSCNPA
                     TLARDSEALLKAGYTIARLAMLDMFPHTGHLESMVLFSRVK"
     gene            8409..11165
                     /gene="barA"
                     /locus_tag="IRB70_003683"
     CDS             8409..11165
                     /gene="barA"
                     /locus_tag="IRB70_003683"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase BarA"
                     /protein_id="HBC0633546.1"
                     /translation="MTNYSLRARMMILILAPTVLIGLLLSIFFVVHRYNDLQRQLEDA
                     GASIIEPLAVSTEYGMSLQNRESIGQLISVLHRRHSDIVRAISVYDENNRLFVTSNFH
                     LDPSSMQLGSNVPFPRQLTVTRDGDIMILRTPIISESYSPDESPSSDAKNSQNMLGYI
                     ALELDLKSVRLQQYKEIFISSVMMLFCIGIALIFGWRLMRDVTGPIRNMVNTVDRIRR
                     GQLDSRVEGFMLGELDMLKNGINSMAMSLAAYHEEMQHNIDQATSDLRETLEQMEIQN
                     VELDLAKKRAQEAARIKSEFLANMSHELRTPLNGVIGFTRLTLKTELTPTQRDHLNTI
                     ERSANNLLAIINDVLDFSKLEAGKLILESIPFPLRSTLDEVVTLLAHSSHDKGLELTL
                     NIKSDVPDNVIGDPLRLQQIITNLVGNAIKFTENGNIDILVEKRALSNTKVQIEVQIR
                     DTGIGIPERDQSRLFQAFRQADASISRRHGGTGLGLVITQKLVNEMGGDISFHSQPNR
                     GSTFWFHINLDLNPNIIIEGPSTQCLAGKRLAYVEPNSAAAQCTLDILSETPLEVVYS
                     PTFSALPPAHYDMMLLGIAVTFREPLTMQHERLAKAVSMTDFLMLALPCHAQVNAEKL
                     KQDGIGACLLKPLTPTRLLPALTEFCHHKQNTLLPVTDESKLAMTVMAVDDNPANLKL
                     IGALLEDMVQHVELCDSGHQAVERAKQMPFDLILMDIQMPDMDGIRACELIHQLPHQQ
                     QTPVIAVTAHAMAGQKEKLLGAGMSDYLAKPIEEERLHNLLLRYKPGSGISSRVVTPE
                     VNEIVVNPNATLDWQLALRQAAGKTDLARDMLQMLLDFLPEVRNKVEEQLVGENPEGL
                     VDLIHKLHGSCGYSGVPRMKNLCQLIEQQLRSGTKEEDLEPELLELLDEMDNVAREAS
                     KILG"
     gene            complement(11396..12736)
                     /gene="gudD"
                     /locus_tag="IRB70_003684"
     CDS             complement(11396..12736)
                     /gene="gudD"
                     /locus_tag="IRB70_003684"
                     /EC_number="4.2.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311674.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HBC0633547.1"
                     /translation="MSSQFTTPVVTEMQVIPVAGHDSMLMNLSGAHAPFFTRNIVIIK
                     DNSGHTGVGEIPGGEKIRKTLEDAIPLVVGKTLGEYKNVLTLVRNTFADRDAGGRGLQ
                     TFDLRTTIHVVTGIEAAMLDLLGQHLGVNVASLLGDGQQRSEVEMLGYLFFVGNRKAT
                     PLPYQSQPDDQCDWYRLRHEEAMTPDAVVRLAEAAYEKYGFNDFKLKGGVLAGEEEAE
                     SIVALAQRFPQARITLDPNGAWSLNEAIKIGKYLKGSLAYAEDPCGAEQGFSGREVMA
                     EFRRATGLPTATNMIATDWRQMGHTLSLQSVDIPLADPHFWTMQGSVRVAQMCHEFGL
                     TWGSHSNNHFDISLAMFTHVAAAAPGKITAIDTHWIWQEGNQRLTKEPFEIKGGLVQV
                     PQKPGLGVEIDMDQVMKAHELYQKHGLGARDDAMGMQYLIPGWTFDNKRPCMVR"
     gene            complement(12757..14097)
                     /locus_tag="IRB70_003685"
     CDS             complement(12757..14097)
                     /locus_tag="IRB70_003685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucarate dehydratase"
                     /protein_id="HBC0633548.1"
                     /translation="MTTQSSPVITDMKVIPVAGHDSMLLNIGGAHNAYFTRNIVVLTD
                     NAGHTGIGEAPGGEVIYQTLVEAIPMVLGQEIARLNKVVQQVHKGNQAADFDTFGKGA
                     WTFELRVNAVAALEAALLDLLGQALNVPVCELLGPGKQRDAITVLGYLFYIGDRTKTD
                     LPYLENTPGNHEWYQLRHQKAMNSEAVVRLAEASQDRYGFKDFKLKGGVLPGEQEIDT
                     VRALKKRFPDARITVDPNGAWLLDEAISLCKGLNDVLTYAEDPCGAEQGFSGREVMAE
                     FRRATGLPVATNMIATNWREMGHAVMLNAVDIPLADPHFWTLSGAVRVAQLCDDWGLT
                     WGCHSNNHFDISLAMFTHVGAAAPGNPTAIDTHWIWQEGDCRLTKNPLEIKNGKIAVP
                     DAPGLGVELDWEQVQKAHEAYKRLPGGARNDAGPMQYLIPGWTFDRKRPVFGRH"
     gene            complement(14099..15451)
                     /gene="gudP"
                     /locus_tag="IRB70_003686"
     CDS             complement(14099..15451)
                     /gene="gudP"
                     /locus_tag="IRB70_003686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GudP"
                     /protein_id="HBC0633549.1"
                     /translation="MSSLSQAASSVEKRTNARYWIVVMLFIVTSFNYGDRATLSIAGS
                     EMAKDIGLDPVGMGYVFSAFSWAYVIGQIPGGWLLDRFGSKRVYFWSIFIWSMFTLLQ
                     GFVDIFSGFGIIVALFTLRFLVGLAEAPSFPGNSRIVAAWFPAQERGTAVSIFNSAQY
                     FATVIFAPIMGWLTHEVGWSHVFFFMGGLGIVISFIWLKVIHEPNQHPGVNQKELEYI
                     AAGGALINMDQQNTKVKVPFSVKWGQIKQLLGSRMMIGVYIGQYCINALTYFFITWFP
                     VYLVQARGMSILKAGFVASVPAVCGFIGGVLGGIISDWLMRRTGSLNIARKTPIVMGM
                     LLSMVMVFCNYVNVEWMIIGFMALAFFGKGIGALGWAVMADTAPKEISGLSGGLFNMF
                     GNISGIVTPIAIGYIVGTTGSFNGALIYVGVHALIAVLSYLVLVGDIKRIELKPVAGQ
                     "
     gene            complement(15886..16335)
                     /locus_tag="IRB70_003687"
     CDS             complement(15886..16335)
                     /locus_tag="IRB70_003687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBC0633550.1"
                     /translation="MAEIGIFVGTMYGNSLLVAEEAEAILTAQGHKATVFEDPELSDW
                     LPYQDKYVLVVTSTTGQGDLPDSIVPLFQGIKDTLGFQPNLRYGVIALGDSSYVNFCN
                     GGKQFDTLLQEQSAQRVGEMLLIDASENPEPETESNPWVEHWGTLLS"
     gene            complement(16353..17135)
                     /gene="truC"
                     /locus_tag="IRB70_003688"
     CDS             complement(16353..17135)
                     /gene="truC"
                     /locus_tag="IRB70_003688"
                     /EC_number="5.4.99.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(65) synthase TruC"
                     /protein_id="HBC0633551.1"
                     /translation="MLEILYQDEWLVAVNKPSGWLVHRSWLDRDEKVVVMQTVRDQIG
                     QHVFTAHRLDRPTSGVLLMGLSSEAGRLLAQQFEQHQIQKRYHAIVRGWLMEEAVLDY
                     PLVEELDKIADKFAREDKGPQPAVTHYRGLATVEMPVATGRYPTTRYGLVELEPKTGR
                     KHQLRRHLAHLRHPIIGDSKHGDLRQNRSGAEHFGLQRLMLHASQLSLTHPFTGEPLT
                     IHAGLDDTWMQALSQFGWRGLLPENERVEFSAPSGQDGEISS"
     gene            complement(17135..17464)
                     /locus_tag="IRB70_003689"
     CDS             complement(17135..17464)
                     /locus_tag="IRB70_003689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqcC family protein"
                     /protein_id="HBC0633552.1"
                     /translation="MTTHDRVRLQLQALEALLREHQHWRNDKPQPHQFNSTQPFFMDT
                     MEPLEWLQWVLIPRMHDLLDNNQPLPGAFAVAPYYEMALATDHPQRALILAELEKLDA
                     LFADDAS"
     gene            complement(18086..18631)
                     /gene="syd"
                     /locus_tag="IRB70_003690"
     CDS             complement(18086..18631)
                     /gene="syd"
                     /locus_tag="IRB70_003690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SecY-interacting protein"
                     /protein_id="HBC0633553.1"
                     /translation="MDDLTAQALKDFTARYCDAWHEEHKSWPLSEELYGVPSPCIIST
                     TEDAVYWQPQPFTGEQNVNAVERAFDIVIQPTIHTFYTTQFAGDMHAQFGDIKLTLLQ
                     TWSEDDFRRVQENLIGHLVTQKRLKLPPTLFIATLEEELEVISVCNLSGEVCKETLGT
                     RKRTHLASNLAEFLNQLKPLL"
     gene            18699..19547
                     /gene="queF"
                     /locus_tag="IRB70_003691"
     CDS             18699..19547
                     /gene="queF"
                     /locus_tag="IRB70_003691"
                     /EC_number="1.7.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent 7-cyano-7-deazaguanine reductase
                     QueF"
                     /protein_id="HBC0633554.1"
                     /translation="MSSYANHQALAGLTLGKSTDYRDTYDASLLQGVPRSLNRDPLGL
                     KADNLPFHGTDIWTLYELSWLNAKGLPQVAVGHVELDYTSANLIESKSFKLYLNSFNQ
                     TRFNNWDEVRQTLERDLSTCAQGKVSVALYRLDELEGQPIGHFNGTCIDDQDITIDNY
                     EFTTDYLENATSGEKVVEETLVSHLLKSNCLITHQPDWGSIQIQYRGRQIDREKLLRY
                     LVSFRHHNEFHEQCVERIFNDLLRFCQPEKLSVYARYTRRGGLDINPWRSNNDFVPST
                     TRLVRQ"
     gene            19659..21023
                     /gene="ppnN"
                     /locus_tag="IRB70_003692"
                     /gene_synonym="ygdH"
     CDS             19659..21023
                     /gene="ppnN"
                     /locus_tag="IRB70_003692"
                     /gene_synonym="ygdH"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide 5'-monophosphate nucleosidase"
                     /protein_id="HBC0633555.1"
                     /translation="MITHISPLGSMDMLSQLEVDMLKRTASSDLYQLFRNCSLAVLNS
                     GSLTDNSKELLSRFENFDINVLRRERGVKLELINPPEEAFVDGRIIRALQANLFAVLR
                     DILFVYGQIHNTVRFPNLNLDNSVHITNLVFSILRNARALHVGEAPNMVVCWGGHSIN
                     ENEYLYARRVGNQLGLRELNICTGCGPGAMEAPMKGAAVGHAQQRYKDSRFIGMTEPS
                     IIAAEPPNPLVNELIIMPDIEKRLEAFVRIAHGIIIFPGGVGTAEELLYLLGILMNPA
                     NKDQVLPLILTGPKESADYFRVLDEFVVHTLGENARRHYRIIIDDAAEVARQMKKSMP
                     LVKENRRDTGDAYSFNWSMRIAPDLQMPFEPSHENMANLKLYPDQPVEVLAADLRRAF
                     SGIVAGNVKEVGIRAIEEFGPYKINGDKEIMRRMDDLLQGFVAQHRMKLPGSAYIPCY
                     EICT"
BASE COUNT         5167 a         5704 c         5088 g         5304 t
ORIGIN      
        1 ctggcctttg atctctttac gaccgttgta cggtgctttt tcgcccagag cttcttcgat
       61 acgaatcagc tggttgtatt tagcaacacg gtcagaacgg ctcatagaac ccgttttgat
      121 ctggcctgca gcagtaccaa cagccaggtc agcgatggta gcgtcttcag tttcgccaga
      181 acggtgagag ataactgcag tgtagccagc gtctttcgcc atcttgattg cagccagagt
      241 ttcggtcaga gaaccgatct ggttgaattt gatcaggatg gagttagcga tacctttttc
      301 gataccttct ttcaggatct tggtgttggt tacgaacagg tcgtcaccaa ccagctggat
      361 tttgtcgccc agaactttgg tctggtatgc gaaaccgtcc cagtcagatt cgtcaagacc
      421 gtcttcgata gatacgatcg gatactgttt ggtcagttct tccaggaagt gagtgaattc
      481 ttcagaggtg aaagctttgt tgccttcgcc agccagaacg tatttaccgt ctttgtagaa
      541 ttcagaagct gcgcagtcca tcgccagagt gatgtctttg cccagttcat aaccagcagc
      601 tttaacagct tcagcgataa cagccagagc ttcagcgttg gaacccaggt tcggcgcata
      661 gccaccttcg tcaccaacag cagtgttcat gcctttcgct ttcagaactt ttgccaggtg
      721 atggaaaact tcagaaccca tgcggatggc ttctttcaca gttttcgcgc caaccggctg
      781 aatcatgaat tcctggatat caacgttgtt gtcagcgtgc tcaccaccgt tgatgatgtt
      841 catcatcgga accggcatgg agtatttgcc cggagtaccg ttcagttcag cgatgtgctc
      901 gtacagcggc atgcctttag cggcagcagc agctttggcg ttagccagag atacagccag
      961 gattgcgttc gcgccgaatt tggatttgtt ttcggtgccg tccaggtcga tcatgatctt
     1021 gtcaatgcca gcctgatctt tggcatcttt gccaatcagt gcctgagcga tcgggccgtt
     1081 taccgcagca acagctttgg ttacgccttt acccaggaaa cgggatttgt cgccatcgcg
     1141 cagttccaga gcttcacggg aaccagtaga agcacctgac ggagcagctg ccataccgac
     1201 gaaaccaccc tccagatgta cttcggcttc aacagtcggg ttaccacggg agtcgatgat
     1261 ttcacgaccg atgattttta cgattttgga cattaggttt tcctcaagtc actagttaaa
     1321 ctgaaactcc agacaaacaa cgcgtaccca gggtacgcgt tgccgttcta acttttttct
     1381 tacttcgcct gacgcttctg gaactcgctg gcggctttca caaagcctgc aaacagcggg
     1441 tgaccatcac gtggagtaga agtaaactcc ggatggaact ggcaagccac gaaccacggg
     1501 tgattcggaa cttcgatgat ctcgaccaac tgatcatccc cggaacggcc cgcaacgcgc
     1561 agacctgcat cttcaatctg tttcaacagc atgttgttga cttcgtaacg gtgacgatga
     1621 cgctcaacaa ttgtcggcgc attgtacagc tggcgaacca ggctatcgtc aaccaactgg
     1681 cactgctgtg cgccgagacg catggtaccg ccgagatcgc tcttctcgct acgaacttca
     1741 acgttgccgt tttcatcgcg ccactcggta atcagcgcca caaccgggta cttacagtct
     1801 ggcacaaatt ccgtagagtt ggcgttctcc atgttggcaa catggcgagc gtaatcaatt
     1861 aacgccacct gcatacccag gcaaatgccc agataaggaa tattgttctc acgcgcaaaa
     1921 cgcgcggtcg taatcatgcc ttctacgcca cgatagccga aaccgccagg tacgaggatt
     1981 gcgtccagac ctttaaggat ttcaacgccg cgcgtttcaa catcttgtga atcgatcagt
     2041 ttgatgttga cgctgacacg attcttcagc ccaccgtgtt tcagtgcttc gatcacggat
     2101 ttgtatgcat ccggcagctc aatgtatttg ccgaccatac caatggtgac ttcacttacc
     2161 ggattcgctt cttcgaagat aacctgttcc cattcggaca gattcgcttc cgggcagttt
     2221 aagctgaatc gtttacaaat ataatcgtcc agcccctgag atttcaacag gcccggaatt
     2281 ttatagatgg aatcgacgtc tttcagagaa ataaccgctt tttccggaac attacagaac
     2341 aatgcaatct tcgcacgttc gttcgccgga acggcgcgat ctgaacgaca aatcaggata
     2401 tcaggctgga taccgattga aagcagctct tttacagagt gctgagtcgg tttggttttg
     2461 acttcaccag acgctgccat gtacggcacc agcgtcaggt gcataaacag ggtgtgctca
     2521 cggccaattt caacagccat ctggcgaatc gcttcaagga acggcaggga ttcgatatca
     2581 cctacagtac cgccgatttc taccagtacc acgtcatgac cttcgccgcc ttccagcacg
     2641 cgctctttga tagcgttagt gatgtgcgga ataacctgta cggttgcgcc gaggtagtcg
     2701 ccacggcgtt ctttacgcag aacgtcagag tagatacgac ccgtggtgaa gttgttgcgg
     2761 cggctcattt tggtacgaat gaaacgctcg tagtgcccca ggtccaggtc ggtttcagcg
     2821 ccgtcttcag taacgaacac ttccccgtgt tggattgggc tcatagtacc tggatcgacg
     2881 ttgatgtacg gatccagttt catgatggtc acattgaggc cacgggcttc aagaatggct
     2941 gcgagggagg ctgcggcaat gcctttaccc agagaggata cgaccccgcc ggtcacaaaa
     3001 atatagttcg ttgtcatgct gaacctgaga agttaggttg aaaagacgat ggaataacca
     3061 ggacgggaaa gcagtatacc cgaacatgac ctgtgccaca aactttcatt atccctcctc
     3121 ttcgccagcg cactattgaa atcaggagtg agaaaatagc ccctttgggg taaatgtttt
     3181 tgacgcaaat caagcgcttg tcatttaaaa aatgacacaa atggcgcttg accgcgtaat
     3241 tcccttagag atcaatttcc tgccgtttta cctgttgcca gacttcttcc attgtttcga
     3301 ggtcaacacc tgtcatttcc agtccacgcg cggcaacaat acgctccact tcgcgaaaac
     3361 gacgctcgaa tttttcgttc gctttttgca atgcgatttc cgcttttgtc cctaaatgac
     3421 gagccagatt gaccgtggca aacagcaggt cacccatttc ctcctccagt ttagcctggt
     3481 cgacaacagc ctgctgcgcc tcgtacatca cctcgtcgat ctcttcgtag actttatcga
     3541 ctaccggacc aagcgtcgtc cagtcgaagc caacgttggc gcaacgtttc tggatttttt
     3601 gcgcacgcat taaagccggt aaactacgag gaatatcatc cagcgccgaa tgctgtgctt
     3661 tctgcgcgcg ttcttcggtt ttgatttgct cccaacgggc gagcacttca ctactgtttt
     3721 cggcagaact gtcagcaaaa acatgcggat ggcgacgctc taatttatcg ctaatagcag
     3781 cgcaaatatc attaaagtca aagcgccctt cttcctgagc catttgtgcg taaaacacca
     3841 cctggaacag cagatcgccc agttcaccgc gcagatcgtc aaaatcttca cgggcgatgg
     3901 cgtccagcac ctcgtaggtt tcttcaaggg tgtaaggcgc aatggtggca aatgtctgct
     3961 ctttatccca cgggcagccg ttttccggat cgcgcaggcg ctgcataata gtgagcaaac
     4021 ggtcgatttg attcattgaa ttgtcctgaa aattgcgggt ctgtcaggtg gaaacctgtg
     4081 accagaatag aagtgagtta gtaacaccta cccaatcagc acgttaattt tggctttaat
     4141 gagttgtaat tcctctgggg caactgttcc tttcttcgtt gctcctcttg cccgccaggc
     4201 gatacttttt acctgatcag ctaacgctac gccatcacgt tcctgaccgg atagaacaac
     4261 ttcgaacgga tatccttttg attgcgttgt acaaggaaca cacagacaca tacctgtttt
     4321 gttgttgtac atgaacggac tcaggacaac agccggacga tgtccggctt gctcgctacc
     4381 ttttgtcggg tcaaaatcaa cccaaatcag atcgcccgta tcgggtacgt atcggcttac
     4441 cattaccaga cttccttatc tttcggctcc ccccagtcga tattctcgtg gaggttttcc
     4501 ggcgtgatgt cgttgaccag ttcagcaagc gtaaatacgg gctctttacg cactggctca
     4561 ataattaatt ttccatccac caggtcaatc ttcacttcat catcaatatt cagattgagc
     4621 gcctgcatta acgtagccgg gatccgcact gcaggagaat ttccccaacg ctttacgcta
     4681 ctgtggatca taaccctttc ctcaaaccgc tatcatatgt agatacagta tatatcaatc
     4741 tacattgtag atacgaacaa gtttcggcct aactcccgtg caaccgacgc gcgtcgataa
     4801 catccggcac ctggttgagt ttacccagca cgcggcccag cacttgcagg ttgtaaatct
     4861 caatggtcat gtcgatggtc gccagttgct gtttggtgtc gctacggctg gcaacgccaa
     4921 gtacgttcac cttctcgttg gcgagaatgg tcgtgatatc acgtaacaac ccactacgat
     4981 cattagccac cacgcggacc accagcgaat atccggcgga gtagctctcg ccccataccg
     5041 cgtcaacaat gcgttctggc gcatgggagc gcagttccgc cagttgttcg caatcggcgc
     5101 ggtgtactga aataccgcgt ccctgggtaa tgaagccgac aatctcatct ccaggaatcg
     5161 gctggcagca gcgcgcgatg tggtgcatca ggttaccgac cccttctacc accacacgac
     5221 cgttatcttt actgcggttt tgcggcgtgt agcttttttg ctgaagctgt ttcagcgcgg
     5281 cggcatcctg ctcttcggca ctcggcttat taaattgcga ttgcaggaag ttcaccatct
     5341 gattgagacg gatatccccg ccaccaattg ccgccagcaa ctcgtcgaca tcattgaagt
     5401 tgtaacgcgg cagcagatgt ttttctgctt ctttcaggct gatccccaga tgttccagct
     5461 cgtcgtcaag gatttgccgc ccagccagaa tgtttttgtc acggtcctgt ttacggaacc
     5521 aggcgtgaat tttcgaacgc ccacggctgg ttgtgacgta accgagattt gggtttaacc
     5581 agtcacggct ggggttcggc tgtttctggg tgataatttc aatctggtcg cccatctgca
     5641 gctggtaggt gaacggcaca atgcgcccgc caatttttgc cccgatgcag cggtgtccga
     5701 catcactgtg gatgtggtaa gcgaagtcca gcggtgttga tcccgcaggc aaatcaacga
     5761 catcaccttt cggcgtaaag acgtacaccc ggtcgtcaaa gacctggctg cgtacttcgt
     5821 cgagcatttc gccggaatca gccatctctt cctgccacgc aatcagttta cgcagccagg
     5881 caattcggtc ttcatgtccc gaacgtgcgc cgccagctgc cgcgccctct ttatatttcc
     5941 agtgcgcagc aacacccaac tctgcatctt catgcatctg tttggtgcgg atttggatct
     6001 caacggtttt gccacccggc cccagaacca cggtatgaat agactgataa ccgtttggtt
     6061 tcgggttagc gacgtaatcg tcgaactcat ccggcaggtg gcgatagtga gtgtgcacta
     6121 tccccagtgc ggcataacaa tcctgtaaac gctcggcgac aatacgtacc gcacgcacat
     6181 caaacagctc atcgaaggcg aggttctttt tctgcatttt gcgccagatg ctgtagatgt
     6241 gtttcggtcg accatacact tcagctttaa cgccttcagc tttcatctca gcgcgcagat
     6301 ggccgacaaa ctcttcgata tagtgttcgc ggtcgagacg gcgttcatgc agcagttttg
     6361 cgatgcgttt gtattcggtc gggtggagat aacggaagca gtaatcttcc agctcccatt
     6421 tcagttgccc aatcccaaga cggttcgcca acggcgcgta gatattggtg cactcttttg
     6481 ccgccagtac gcgttcatct tccggcgcgt cttttacttc gcgcagatga gcaatacgct
     6541 ctgccagttt gatgaccacg cagcggaaat catcgaccat cgccaataac atccggcgaa
     6601 cgttatcgac ctgttcggag gaaacagaat cggtatgcgt cgctttcagc tggcggatcg
     6661 ccgccatatc acgcacgccg tgaataaggt taacgaccga cttaccgacg ctctcacgca
     6721 gcacatcttc gctgactacg ttggcatccg ccagagggaa cagcagcgcc gcccgcagcg
     6781 tgtcaatgtc catacttaat gtcgagagga tctccaccat ctcaacacca cgccacaata
     6841 acagactggc atccggatgc ccctgcgtct gttgcagaca atatgcccag gtttcggcta
     6901 agcactcaca cgacttctgg ctggtaatac ccagacttgc gatccatttt tccggatcaa
     6961 attcaccagc cttattgata tgtgcacttc ttaccgcaac catcgtcctc tcctttaggg
     7021 accagacctg ccgaaatcgg caaatcgcaa ctatttaacg cgcgagaaaa gtaccatcga
     7081 ttccagatgt cccgtgtgtg ggaacatatc cagcatcgcc agtcgcgcaa tggtatatcc
     7141 tgcttttaat aacgcttcgc tatcccgagc cagcgttgca gggttacagg atacataaac
     7201 tatacgaata ggttccagtt ttataatttg ctgcataaca cctgcggcac ctgctcgcgc
     7261 cgggtccaac aacactttat cgaagccgtt tttcgcccac ggctgctttg tgacatcttc
     7321 ttcaagattt tcgtgataaa acgtcacatt gtgtaagcca ttaagacgcg cattctgctg
     7381 gcctttttca accagcgccg gaacgccttc tacaccgacc acactggcag cttgtgtcgc
     7441 caatggcagt gtaaagttgc ccataccgca gaacagatcc agtacgcgat cttcaggttg
     7501 cacatccagc cattccaacg cacgcgctac cattttttgg ttcacacccg cattgacctg
     7561 aataaaatcg cgcgggctaa aagttaagcg caacccattt gagtcatacc agggcatctc
     7621 accagagacg gtttcgagta tctcactatc gggggcgaga tacagatcca gtccttcaga
     7681 atgcgaaaag cattccagtt tttcgcgatc tgccgaactt agcggtgcgg tatggcgcaa
     7741 aatcattagc gtgccgctgg ttgcctgtac cagttcaaca tgaccaagat ggcgcatagc
     7801 ttgtaagctg cccaggcatg ccctgacttt gggcagcaat gcttcaagtt ggggcactaa
     7861 aatggggcat tgtttaacgt cgacaatgtc actggagccc gctttgcgaa accccatctg
     7921 aagttgctgt gttttcggta agtagttcag acttaaacgc gcgcgacggc gatagcccca
     7981 gggaacatcg gcgatcactt cagagacttc gtgtttcatt aatcgggcga gtgccgcact
     8041 tttgcttcgc tgctgtaaat ccacactggc gtgttgttgc tgacagccgc cgcatacgcc
     8101 aaaatgagga cagcgtggcg tttcgcgttc cggactatcg cttaaccggc gtacgacttt
     8161 agcgcgggca tactgttttt tatcttcagt aacagtaact tccgcgtttt cctgcggcaa
     8221 taatccgggg ataaataatg ttttgccgtt atgtcgcgcc acaccctgac caaaagagtc
     8281 gaggtcgttg actgaaacgg ttatgatctg acgcgtcgtc gtgcgtcgtt ttgcagagta
     8341 gaattgcgcc attggcgaga ctttctcaat ttaacagtgt gaccttaatt gtcccataac
     8401 ggaactccat gaccaactac agcctgcgcg cacgcatgat gattctgatc ctggcaccga
     8461 ccgtccttat tggtttattg ctgagtatct ttttcgtcgt gcatcgctat aacgacttgc
     8521 agcgtcaact ggaagatgcc ggtgccagca ttattgagcc gcttgcagtt tctactgaat
     8581 atggcatgag tctgcaaaat cgcgaatcta tcggtcagtt aataagcgta ctgcatcgtc
     8641 gccattccga tattgttcgc gcgatttcgg tttatgatga aaataaccga ctctttgtca
     8701 cctccaattt tcatcttgat ccctcatcaa tgcagctcgg cagcaacgtg ccgtttcctc
     8761 gccagctcac tgtcactcgt gacggcgata ttatgatcct ccgcacgccg attatttctg
     8821 agagttactc ccccgacgaa tcgcccagta gcgatgccaa aaatagtcaa aatatgttgg
     8881 gatatattgc gctggagctg gatcttaaat cggttcgctt gcagcaatat aaagagatct
     8941 ttatttccag cgtgatgatg ctgttttgta tcggtattgc gcttattttt ggctggcgct
     9001 taatgcgcga tgtaaccggt ccgattcgca acatggtgaa taccgtcgac cgcatccgtc
     9061 gcgggcaact cgacagccgg gtggaaggat ttatgcttgg tgagctggat atgctgaaaa
     9121 acggtatcaa ctcgatggca atgtcgctgg cggcttatca cgaagagatg caacacaata
     9181 tcgaccaggc gacgtccgat ctgcgtgaga cgctggagca aatggagatt cagaacgttg
     9241 agttggatct ggcgaaaaag cgcgcccagg aagcggcgcg tattaaatcc gagtttctgg
     9301 caaatatgtc acacgagctg cgtacaccac tgaatggtgt tattggcttt acccgcctga
     9361 cgctgaaaac agaattaaca ccaacgcagc gcgatcacct gaatacgatt gaacgttcgg
     9421 caaataattt gctggcaatt attaatgatg ttctcgactt ctcgaaactg gaagcaggta
     9481 agctgattct ggaaagtatt ccattcccac tacgcagcac gctggatgaa gtcgttaccc
     9541 tgctggcaca ttcttctcac gataaagggc tggaactgac gctcaatatt aaaagcgacg
     9601 tgcctgataa cgtgatcggc gacccactac gattacagca aatcatcact aacctggtgg
     9661 ggaatgcaat taaattcacc gagaatggca acattgatat tctggtagaa aaacgtgcgc
     9721 tgagtaatac caaagtgcaa attgaagtgc agattcggga taccggcatt ggtattcctg
     9781 aacgcgatca atcgcgctta ttccaggcct tcagacaggc tgatgccagt atttcccgcc
     9841 gtcatggtgg caccgggctg gggctggtga ttacacaaaa actggttaat gaaatgggcg
     9901 gcgatatttc gttccatagc cagccgaatc gcggttcaac tttctggttc cacattaatc
     9961 tcgatctgaa cccgaacatt attatcgaag ggccatccac ccagtgcctc gccggcaagc
    10021 gcctggccta tgtcgaacca aactccgcag cagcgcaatg cacgctggat attttaagtg
    10081 aaacgccgct ggaagtggtt tatagcccaa cgttctctgc gctgcctccc gcgcattacg
    10141 acatgatgtt gttaggcatc gcggtgacct tccgcgagcc gctaacaatg caacatgagc
    10201 gattagcgaa agcagtatcg atgaccgatt ttctgatgct ggcacttcct tgccatgcac
    10261 aagtcaatgc tgaaaaactt aagcaagatg gtatcggcgc gtgtctgctg aaaccattaa
    10321 cacctacgcg cctgttacct gccctgacgg aattttgtca tcacaaacaa aacacgcttt
    10381 tgcctgtaac cgatgaaagt aagctggcaa tgacagtcat ggcggttgat gacaaccccg
    10441 ctaacctgaa acttatcggc gcattgctgg aagatatggt gcaacatgtg gaactttgcg
    10501 atagcgggca tcaggcggtt gaacgggcga aacagatgcc gttcgatttg atcttaatgg
    10561 atattcaaat gccggacatg gacggcattc gggcctgcga actcatccac cagctccccc
    10621 atcagcaaca aacgccggtt atcgcggtaa cggcgcatgc aatggccggg caaaaagaga
    10681 agctgcttgg cgcagggatg agcgattatc tggcgaaacc gattgaagaa gagcgattgc
    10741 ataatttgtt gttgcgctat aagcctggca gcggtatttc ctctcgcgtc gtgacgcccg
    10801 aagtcaacga aattgtggtg aacccgaatg cgaccctcga ctggcaactg gcactacgcc
    10861 aggcagcagg aaaaaccgat ttagcgcgcg atatgctgca aatgttactc gatttcctgc
    10921 ctgaagttcg caacaaagtt gaggaacagc tggttggaga aaacccggaa ggcctggttg
    10981 atttgattca taaactgcat ggcagttgcg gctatagcgg tgtgccgcgt atgaagaatc
    11041 tctgccaact gatcgaacaa cagctacgta gcggtactaa agaagaagat ttggagccgg
    11101 agctgctgga actgttggac gagatggata atgtagcgcg cgaagccagc aaaattctcg
    11161 ggtaacggac gtcttgtcga gtagcaatcg gctttttatg aagctggttt cagactggtg
    11221 acaaagtgcc tgtgtttatg ccggatgcgg cgttaacgcc ttatcctgcc tacaaaatca
    11281 attaaattca atgaattaaa aagtatgttg gcctgatacg tagcgcaaca ggcaattttg
    11341 cgtttggcat cagtctcaaa ccggctcctg acagagccgg tttttgtttt cagtcttaac
    11401 gcaccatgca cgggcgcttg ttatcaaacg tccagccagg aatcaggtac tgcattccca
    11461 tcgcatcgtc acgcgcgcca agcccgtgtt tctgatacag ctcgtgggct ttcatcacct
    11521 gatccatatc gatttctacg cccaatcctg gtttttgcgg cacctgtacc agcccgcctt
    11581 tgatctcaaa cggttctttg gtcagacgct gattgccttc ctgccagatc cagtgcgtat
    11641 caatagcagt aattttaccc ggtgcagcag cggctacatg ggtaaacatc gccagggaaa
    11701 tatcgaagtg gttgttagag tgtgaacccc aggtcaggcc aaattcatgg cacatttgcg
    11761 ccacacgtac cgaaccttgc atcgtccaga aatgcggatc cgccagcggg atatcaacgg
    11821 attgcaggga gagcgtatgg cccatctgcc gccagtcggt ggcgatcata ttggttgcgg
    11881 tcggcaggcc agtcgcgcga cggaactctg ccatcacttc acgcccggag aaaccttgct
    11941 ccgcaccaca cggatcttct gcataagcca gcgaaccttt caggtattta ccaattttaa
    12001 tcgcttcgtt cagcgaccag gcaccgttag gatcgagggt aatacgcgcc tgtgggaagc
    12061 gttgcgccag tgccacaata gattctgctt cttcttcccc ggccagtaca ccgcccttca
    12121 gtttgaaatc gttgaagcca tatttttcat atgccgcttc cgccaggcgc accaccgcat
    12181 ccggcgtcat cgcttcttcg tgacgcaggc gataccagtc acattgatca tccggctggc
    12241 tttgatacgg cagcggtgtg gctttgcgat taccgacgaa gaacagataa ccgagcattt
    12301 cgacttcgct acgctgttga ccatcgccca gcagcgatgc cacgttaacc cccagatgct
    12361 gccccagcag atccagcatt gccgcttcta tcccggtaac cacatgaata gtggtccgca
    12421 ggtcaaatgt ctgcaaaccg cgcccgccgg catcacgatc ggcaaatgta ttacgcacca
    12481 gcgtcagaac gtttttgtat tcacccagcg ttttacccac caccagcgga atcgcatctt
    12541 ccagcgtttt acggattttc tcgccgccgg gaatttcccc taccccagtg tgaccagaat
    12601 tatctttgat aatcacaata ttacgcgtga agaacggtgc gtgtgcacca ctcagattca
    12661 tcagcatact gtcatggccc gccaccggga tgacctgcat ttcagtaaca acaggcgtcg
    12721 taaattgaga actcatattt atgtcctttt tcaaaatcaa tgacggccga aaacgggacg
    12781 tttacggtca aaggtccagc cggggatcag gtactgcatc gggcccgcgt cgttacgcgc
    12841 accgccaggc agacgtttat aggcctcatg cgccttttgt acctgctccc agtccagttc
    12901 cacgcccaga ccgggcgcat caggaacggc aatttttcca tttttaatct ccagcggatt
    12961 tttggtcagg cgacaatcgc cctcctgcca aatccagtgg gtatcgatag cggtaggatt
    13021 acccggtgcc gccgcgccca catgggtaaa catcgccaga gagatatcaa agtggttatt
    13081 ggaatggcag ccccaggtca gcccccagtc gtcgcaaagc tgcgctacgc ggactgcacc
    13141 ggaaagcgtc cagaagtgcg ggtcggcaag tggaatatct accgcattga gcatcaccgc
    13201 atggcccatt tcgcgccagt tggtggcgat catattagtc gcgacgggca agccggtcgc
    13261 ccgccgaaat tccgccatca cttcacgtcc ggagaaaccc tgttctgcgc cacacggatc
    13321 ttcggcatag gtgagaacat cattcagccc tttgcacaga gaaatagctt catcaagcag
    13381 ccatgctccg ttgggatcaa cggtaatccg cgcatccggg aagcgtttct tcaatgcacg
    13441 aacagtgtcg atttcttgct cgccaggtaa cactccgccc ttaagtttga aatctttaaa
    13501 gccatagcga tcctgtgaag cttccgccag acgcacaacg gcttcgctgt tcatcgcttt
    13561 ctgatgccgc aattgatacc actcatggtt gcccggagta ttttccagat aaggaagatc
    13621 ggttttggtc cgatcaccga tataaaacag ataaccgagg acggtaatag catcgcgttg
    13681 cttgcctggc cctaacagtt cgcagaccgg aacattcagc gcctgaccta gcaggtcaag
    13741 caaggcggct tccagcgccg ccacggcatt aacgcgcaat tcaaaagtcc aggcaccttt
    13801 gccgaaggta tcaaaatcgg ctgcctgatt acctttatgc acctgctgaa ccactttatt
    13861 cagtcgtgcg atctcctggc ccaacaccat cggaatagcc tcgaccagtg tttgataaat
    13921 cacctctccg cccggcgctt caccaatgcc ggtatgcccg gcgttatcgg tgagtaccac
    13981 aatattgcgg gtgaaatatg cgttatgtgc accaccaata ttaagcaaca tgctgtcatg
    14041 tccggcgacc ggaatgactt tcatatcagt aataacagga ctggattgtg tcgtcatctt
    14101 attgccccgc gacaggtttc agctcaatac gcttgatatc gcccaccagc accaggtagc
    14161 tgagtaccgc gattaaggca tgaacaccaa cataaatcag cgccccatta aaggagccag
    14221 tcgtgccaac gatataacca attgcgattg gcgtgacgat gccagaaatg ttaccgaaca
    14281 tgttgaacag gccaccggaa agaccgctga tctcttttgg cgcggtatct gccattactg
    14341 cccaacccag cgccccgatg cccttaccga agaaggccag cgccataaag ccgatgatca
    14401 tccactcaac gttgacgtag ttgcagaaca ccatcaccat cgacagcaac atgcccatta
    14461 cgatcggtgt tttacgcgca atgttcagcg atcccgtgcg gcgcatcagc cagtcggaaa
    14521 taatcccacc cagcacaccg ccgataaaac cgcaaaccgc cggaacggaa gccacaaagc
    14581 ccgctttcag aatcgacatc ccgcgtgcct gcaccagata aaccgggaac caggtaataa
    14641 agaagtaagt cagggcgttg atacagtact gaccgatata aacgccgatc atcatccgtg
    14701 acccgagcag ctgtttgatc tgcccccact tcacgctgaa cggtacttta actttggtgt
    14761 tttgctgatc catattgatc agcgcgccac ccgccgcgat gtactccagc tctttctgat
    14821 ttacacccgg atgttgattt ggctcgtgga tgactttcaa ccagataaag ctgatgacaa
    14881 tgcccagacc gcccataaag aagaagacgt gtgaccagcc cacttcatgc gtcagccagc
    14941 ccataatcgg cgcgaagatc accgttgcga agtattgagc ggagttaaaa atcgacaccg
    15001 ccgttcccct ttcctgcgcc ggaaaccagg ccgctacaat gcgactgtta ccggggaaag
    15061 atggcgcttc agcaagcccg accaggaagc gcagcgtaaa cagggcaacg ataatgccga
    15121 atccactaaa aatatcgacg aagccttgca gcaaggtaaa catcgaccag ataaagatcg
    15181 accagaagta gacacgtttt gaaccaaaac gatccagcaa ccaaccacca gggatctgcc
    15241 cgataacata agcccatgag aaagcagaga acacatagcc cattcccaca ggatcaaggc
    15301 cgatatcttt ggccatttcc gaaccggcga tagagagcgt agcgcggtcg ccgtagttga
    15361 aggatgtgac gataaacaac atcaccacta tccagtaacg agcattcgtg cgtttttcca
    15421 cactgctcgc agcctgactt aaagaactca ttgttgcact cctgaaaatt cgcgttagcc
    15481 acgctcactc tggactgcga catcgccagg aaatcagagg tgacgtaggg tgttttttgc
    15541 cgtttttata ggtcgttcgc cgaatgcggc gcgtgtttat atctggcaat agcagtataa
    15601 aaagcgcgcc atagcggctc accgtgcaac aacacaacat taatgcgttc aatgaggccc
    15661 gattttggca ttagccctgg acggtggaat ccacttcacg gaaatgaaaa caagaacaag
    15721 aaaggaaggg ttaaaacgaa gaaataaaga agagtatgaa atggatcgct tgactccagg
    15781 caaacgccag taaaaatccg cactatgaag cagtttttac tggcatttgc ctgaaaagat
    15841 tcgattcagc actgctaaaa cggcatttac cgctcgctga acatatcagg acaacagcgt
    15901 gccccaatgt tcgacccacg gatttgattc cgtttccggt tccgggttct cactggcgtc
    15961 aatcaacagc atttctccca cccgctgagc gctctgttcc tgcaacaagg tatcgaactg
    16021 tttgccacca ttgcagaaat tcacataact actgtcgccg agcgcaatca cgccataacg
    16081 cagattcggc tggaagccca gggtatcttt aattccctga aagagcggca caatgctatc
    16141 aggaaggtcg ccctgcccgg tcgtggacgt aaccaccaga acatacttat cctgataggg
    16201 cagccagtcg cttaattcag gatcttcaaa taccgttgct ttgtggccct gcgcggtcag
    16261 aattgcttcc gcttcttccg ccactaacag cgaatttccg tacatagtgc cgacaaaaat
    16321 accaatttcc gccataccgt tttctccctg gattaggaac ttatctctcc atcctgaccc
    16381 gatggcgcac tgaactcaac cctttcattt tcaggaagca gaccccgcca gccaaattgt
    16441 gataacgcct gcatccaggt gtcgtccagg cccgcgtgaa tagtcagcgg ctcgccagta
    16501 aaaggatgcg tcaatgacaa ctgactggca tgcagcatta accgctgaag gccaaaatgt
    16561 tcagcaccgc tgcgattctg gcgtaaatca ccatgtttgc tgtcgccaat aatcgggtgg
    16621 cgcaaatggg caagatggcg acggagctgg tgcttacgtc cggttttcgg ctccagttcc
    16681 accaggccgt agcgcgtggt cgggtaacgt ccggtcgcta ccggcatttc tacggtcgcc
    16741 agaccgcgat aatgcgtcac tgctggctgc gggcctttat cttcgcgggc aaatttatca
    16801 gcgattttgt ccagttcttc caccagtgga taatccagca ccgcttcttc catcaaccag
    16861 ccgcgcacaa tcgcatggta acgtttctgg atttggtgct gttcaaactg ttgtgccagc
    16921 agccgtccgg cctcgctgga taatcccatc aacaacacac cagaagtggg tcggtccaga
    16981 cgatgagcag taaacacatg ctggcctatc tggtcacgca cggtttgcat gaccactact
    17041 ttctcgtcgc gatccagcca gctgcggtga accagccagc cggagggttt atttaccgca
    17101 accagccatt catcctgata gagtatttcc agcattagct cgcatcatcc gcaaaaagag
    17161 catccagttt ttccagctca gccagaataa gcgcgcgttg cgggtggtcc gtcgccagcg
    17221 ccatttcata atagggtgca acggcaaaag cgcccggtaa cggctggttg ttatctaaca
    17281 aatcatgcat tcgcgggatc agcacccact gcaaccactc cagtggttcc atggtgtcca
    17341 taaagaacgg ttgggtactg ttaaattgat gcggctgggg tttatcgttg cgccagtgct
    17401 gatgttcacg cagtaacgct tcaagcgcct gcaactggag acgaacgcgg tcatgagtgg
    17461 tcataaagca acctcaataa gaaaaactgc cgcgaaggat agcaggaata aaaaaaggga
    17521 gcactgtatt cacagtgctc ccggttcgtt tcgcagcatt ccagctactt ttgttgctcc
    17581 ctgctcatcc ttgacaactt ttcctctggc cttgcggcca atcgttcatc ctgaactatt
    17641 gcttcctgct cacaccaccc cgatgtgata cttcatcctg aagtgtccct ggccttcctg
    17701 acccaccgaa tcatcctgac cggttctcat tctccatcct ggaggtgtcc tttaacgcgt
    17761 cctgcgtcat cctcttcgct tcatccagaa gcctttccct gaaacaccat cctggtgtgt
    17821 ccttcagaag tgtcatcatc ctgatgttca cttcgttgtc tgactccctg tcgacgaaga
    17881 tagaatcgtc tttttcgcga agtcttacaa ggcgcttaca gacaatgcct taaggaaaat
    17941 ttcatatgaa agttaagaat tgacaagcaa tatattgatt ttaaatgaaa ataacgattc
    18001 ttatcttttt aagtattcgc ttatttcctg gcgatctcct acagagtctg taagagatct
    18061 ctcacaacaa gatggggtat ttggattaca gaagaggctt aagttgatta aggaattccg
    18121 caagatttga ggctaaatgc gtccgtttgc gtgttcccag cgtctctttg cacacttcac
    18181 cggagagatt acacaccgag atgacctcta actcttcttc cagcgtcgcg ataaatagcg
    18241 tgggcggcag ttttagcctt ttctgagtca ccagatgacc aatcagattt tcctgcaccc
    18301 gacggaagtc gtcttcactc caggtttgca gcaatgtcag tttgatatcg ccaaactgcg
    18361 cgtgcatatc cccggcaaac tgagtcgtat aaaaggtatg aattgtgggt tgtatcacaa
    18421 tatcaaaagc acgttcaacc gcgtttacat tttgttcccc ggtaaacggc tggggttgcc
    18481 agtatacggc gtcttcggtg gttgaaataa tgcacggtga aggaacaccg tacagttcct
    18541 cactcaacgg ccagctttta tgctcttcat gccacgcatc gcagtagcgt gcagtaaaat
    18601 ctttcagggc ttgtgcggtc aaatcgtcca ctaatttctc tcttcactta aaccagatac
    18661 acttgtcgtt tagtttatct ggtttatgac ggtgaaacat gtcttcttat gcaaaccatc
    18721 aggcacttgc gggcctgact cttggaaaat caaccgatta ccgggatacc tatgacgcca
    18781 gcctactgca aggcgttccg cgtagtctga atcgcgatcc gctgggtctg aaagcggata
    18841 acctgccttt tcacggtacg gatatctgga cgctgtatga actttcctgg ctgaatgcga
    18901 aaggtttgcc gcaggtcgcc gtcggtcacg ttgaacttga ttacaccagc gcaaatctga
    18961 ttgagtcgaa gagttttaag ctctatctca acagttttaa ccagacgcgt tttaataact
    19021 gggatgaggt gcgccagacg ctggagcgcg acttaagcac ttgcgctcag ggtaaggtta
    19081 gcgtggcgtt atatcgtctt gatgaactgg aaggccaacc gataggtcat ttcaatggca
    19141 cttgcattga tgaccaggat atcactatcg ataactatga attcactact gactatctgg
    19201 agaatgccac cagtggcgaa aaagtagtag aagagacgct cgtcagccac ctgctgaaat
    19261 caaactgcct gatcacccat caaccagatt ggggatcgat ccaaattcag tatcgtggac
    19321 gccaaattga cagagaaaaa ctgctgcgtt acctggtctc tttccgtcat cacaacgagt
    19381 tccacgaaca gtgcgtggaa cgcatcttta atgacctgtt acgcttctgc cagccagaaa
    19441 aattgagcgt ttacgcacgt tatacccgtc gtggcggtct ggacattaac ccgtggcgca
    19501 gtaataacga ttttgtccca tcgaccacaa gactggttcg tcaataaatt ttttctcaat
    19561 tttgcgtgct ggattcacgc agaaggttgt gaaaggtcat caggcagggc tattgtaatc
    19621 aaagggaatg acgatattcg tcccataagg agtttttctt gattacacat attagcccgc
    19681 ttggctccat ggatatgttg tcgcagctgg aagtggatat gcttaaacgc accgccagca
    19741 gcgacctcta tcaactgttt cgcaactgtt cacttgccgt actgaactcc ggtagtttga
    19801 ccgataacag caaagaattg ctgtctcgtt ttgaaaattt cgatattaac gtcctgcgcc
    19861 gtgaacgcgg cgtaaagctg gaactgatta atcccccgga agaggctttt gtcgatgggc
    19921 gaattattcg cgctttgcag gccaacttgt tcgcggttct gcgtgacatt ctcttcgttt
    19981 acgggcaaat ccataacacc gttcgttttc ccaatctgaa tctcgacaac tccgtccaca
    20041 tcactaacct ggtcttttcc atcttgcgta acgctcgcgc gctgcatgtt ggtgaagcgc
    20101 caaatatggt ggtctgctgg ggcgggcact caattaacga aaacgagtat ttgtatgccc
    20161 gtcgcgtcgg gaatcagctg ggcctgcgtg agctgaatat ctgcaccggc tgtggtccgg
    20221 gagcgatgga agcgccgatg aaaggtgctg cggtcggaca cgcgcagcag cgttacaaag
    20281 acagtcgctt tattggtatg acagagccgt cgattatcgc cgctgaaccg cctaacccgc
    20341 tggtcaacga attgatcatc atgccagata tcgaaaaacg tctggaagcg tttgtccgta
    20401 tcgctcacgg tatcattatc ttccctggcg gtgtgggtac agcagaagag ttgctgtatt
    20461 tgctgggaat tttaatgaac ccggccaaca aagatcaggt tttaccattg atcctcaccg
    20521 gcccgaaaga gagcgccgac tacttccgcg tactggacga gtttgtcgtg catacgctgg
    20581 gtgaaaacgc gcgccgccat taccgcatca tcattgatga cgccgctgaa gtcgctcgtc
    20641 agatgaaaaa atcgatgccg ctggtgaaag aaaatcgccg cgacacaggc gatgcctaca
    20701 gctttaactg gtcaatgcgc attgcgccag atttgcaaat gccgtttgag ccgtctcacg
    20761 agaatatggc taatctgaag ctttacccgg atcaacccgt tgaagtgctg gctgccgacc
    20821 tgcgccgtgc gttctccggt attgtggcgg gtaacgtaaa agaagtcggt attcgcgcca
    20881 ttgaagagtt tggtccttat aaaatcaacg gcgataaaga gattatgcgt cgtatggatg
    20941 acctgctaca gggttttgtt gcccagcatc gtatgaagtt gccaggctca gcctacatcc
    21001 cttgctacga aatctgcacg taatctccct cccccggtga cgtttgttgc cgggttttct
    21061 cgtttttggt cacataccca tcaatttatt tcatttgtta tatgaatgtt tcttaccccc
    21121 ctcacgcgat aaatatcatt acagttaata tgtcatacaa tttatgttgt aacgcaaacg
    21181 tttccctatt ttcataaacc acattttatc gctatgaaaa agaaattatc gccatgatta
    21241 actaaaagta ttgatttttt cag
//
LOCUS       DADXDL010000087        21197 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.087, whole genome shotgun sequence.
ACCESSION   DADXDL010000087 DADXDL010000000
VERSION     DADXDL010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21197)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21197)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21197
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.087"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..2747)
                     /locus_tag="IRB70_003693"
     CDS             complement(<1..2747)
                     /locus_tag="IRB70_003693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HBC0633556.1"
                     /translation="MGKGGGKAHTPREAKDNLKSTQMMSVIDAIGEGPIEGPVKGLQS
                     ILVNKTPLTDTDGNPVIHGVTAVWRAGEQEQTPPEGFESSGAETGLGVEVTKAKPVTR
                     TITSANIDRLRVTFGVQSLVETTSKGDRNPASVRLLIQLQRNGNWVTEKDVTINGKTT
                     SQFLASVILDNLPPRPFNIRMVRETADSTTDQLQNKTLWSSYTEIIDVKQCYPNTAIV
                     GLQVDAEQFGGQQMTVNYHIRGRIIQVPSNYDPEKRTYSGIWDGSLKPAYSNNPAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYAIGQYCDQTVPDGFGGTEPRMTFNAYLAQQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDVVWPYTNSDVVVDDNGVGFRYSFSAL
                     KDRHTAVEVNYTDPQNGWQTSTELVEDPEAILRYGRNLLKMDAFGCTSRGQAHRAGLW
                     VIKTELLETQTVDFTLGSQGLRHTPGDIIEICDNDYAGTLTGGRVLSIDAATRTLTLD
                     REVTLPETGAATVNLINGSGKPVSVDITEHPAPDRIQVSTLPDGVETYGVWGLSLPSL
                     RRRLFRCVSVRENTDGTFAITAVQHVPEKEAIVDNGARFEPQSGSLNSVIPPAVQHLT
                     VEVSAADGQYLAQAKWDTPRVVKGVRFSLRLTSGKGTDARLVTTAITADTEHRFSGLP
                     LGEYTLTVRAINSYGQQGEPATTTFRITAPAAPSRIELTPGYFQITATPHLAVYDPTV
                     QFEFWFSEKRIADIRQVETAARYLGSALYWIAASINIKPGHDYYFYIRSVNTVGKSAF
                     VEAVGRASDDAEGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITNVSNEI
                     TQTVNKKLENQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIENTP
                     AG"
     gene            complement(3091..3723)
                     /locus_tag="IRB70_003694"
     CDS             complement(3091..3723)
                     /locus_tag="IRB70_003694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001188718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HBC0633557.1"
                     /translation="MCLHGDLQRFGRRLSLYVNTAAEAIRALSLQVPGFRRQMNEGWY
                     QIRIAGYDTAPEAVYARLHEQLGEGTVIHIVPRLAGAGKGGLQIVLGAAAIVGSFFTA
                     GASMALWGTALSAGGFSATTMLFSLGASMILGGVAQMLAPKAKTPEYKSTDNGKQNTY
                     FSSLDNMIAQGNPMPVPYGEMLVGSRRISQDISTRDEGGGGKVVVIGRQG"
     gene            complement(3669..4412)
                     /locus_tag="IRB70_003695"
     CDS             complement(3669..4412)
                     /locus_tag="IRB70_003695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310264.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633558.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVISTPEGEWYIPCVNISAEPE
                     AYFRIAPEDWLRAEMQGEIVALVHSHPGGLPWLSEADRRLQIKSALPWWLVCRGDIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGTEMPDFHREDDWWRNGQNLYLDNMAVT
                     GFYRVPLSSAQAGDILLCCFGASVPNHAAIYCGNGELLHHLPEQLSKRERYSEKWQRR
                     THSVWRHRHWHASAFTGIYNDLAAASACM"
     gene            complement(4423..5121)
                     /locus_tag="IRB70_003696"
     CDS             complement(4423..5121)
                     /locus_tag="IRB70_003696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HBC0633559.1"
                     /translation="MQDIREESLNESVKSEQSPRVVLWEIDLTVQGGERYFFCNELNE
                     KGEPVTWQGRKYEAYPIDGSGFEMNGRGSSARPSLTVSNLFGLVTGMAEDLQSLVGAT
                     VVRRRVYARFLDAVNFVAGNPEADPEQELSDRWVVEQMSQLTAMTASFVLATPTETDG
                     ALFPGRIMLANTCMWDYRGDECGYNGPAVADEFDNPTTDIRKDRCSKCMRGCELRRNV
                     GNFGGFLSINKLSQ"
     gene            complement(5121..5450)
                     /locus_tag="IRB70_003697"
     CDS             complement(5121..5450)
                     /locus_tag="IRB70_003697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633560.1"
                     /translation="MKTFRWKVKPDMEVNSQPSVREVRFGDGYSQRMAAGLNADLKTY
                     RVTLSVTREEARHLEAFLAEHGGWKAFLWKPPYAYRQIKVTCAGWSARVGMLRVEFSA
                     EFKQVVN"
     gene            complement(5447..8020)
                     /locus_tag="IRB70_003698"
     CDS             complement(5447..8020)
                     /locus_tag="IRB70_003698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001621422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBC0633561.1"
                     /translation="MSQPVGDLVIDLSLDAVRFDEQMSRVRRHFSGLDTDARKTASAV
                     EQGLSRQALAAQKAGISVGQYKAAMRTLPAQFTDIATQLAGGQNPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGVTSLAVATGALVYAWYQGDSTLSAFNKTLVLSGNQS
                     GLTADRMLTLSRAGQAAGLTFNQARESLAALVNAGVRGGEQFDAINQSVARFASASGV
                     EVDKVAEAFGKLTTDPTSGLMAMARQFRNVTAEQIAYVAQLQRSGDEAGALQAANDIA
                     TKGFDEQTRRLKENMGTLETWADKTGKAFKSMWDAILDIGRPESSADMLASAQKAFDE
                     ADKKWQWYQSRSQRRGKTSSFRANLQGAWDDRENARLGLAAATLQSDMEKAGELAARD
                     RAERESSQLKYTGEAQKAYERLLTPLEKYTARQEELNKALKDGKILQADYNTLMASAK
                     KDYESTQKKPSGVKVSAGERQEDQAHAALLALETELRTLEKHSGVNEKISQQRRDLWE
                     AENQYVVLKEAATKRQLSEQEKSLLAHEKETLEYKRQLAELGDKIEHQKRLNELAQQA
                     ARFEQQQSAKQAAISAKARGLTDRQAQRESEEQRLREVYGDNPAALAKATSALKNTWS
                     AEEQLRGSWMAGMKSGWGEWAESATDSFSQVKNAATQTFDGIAQNMAAMLTGSEQNWR
                     GFTRSVLSMLTEIFLKQAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAANFHFATG
                     GFTGTGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYAEGGYVGGAGSPAQMR
                     RAEGINFNQNNHVVIQNDGPNGRAGPQLMKAVYEMARKGAQDELRLQLRDGGMLSGSG
                     G"
     gene            complement(8001..8414)
                     /locus_tag="IRB70_003699"
     CDS             complement(8001..8414)
                     /locus_tag="IRB70_003699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309140.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HBC0633562.1"
                     /translation="MGRPDWRAMLAGMTSTEYADWHRFYRTHYFQDTQLDMHFSGLTY
                     AVLSLFFCDPDMHPSDFSLLVPRHEEEQVERPDEDKMLMQKAAGLAGGVRFGGDGGRD
                     ILSSADVADVMVDDAALMMASAGIPGGVRYVPAGW"
     gene            complement(8441..8872)
                     /locus_tag="IRB70_003700"
     CDS             complement(8441..8872)
                     /locus_tag="IRB70_003700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HBC0633563.1"
                     /translation="MFLKTEQFEYNGVSVTLSELSALQRIEHLALLKRRAEQAESCGN
                     LQVSVEDLVRTGAFLVAMSLWHNHPQKTQSPSMNEAVMKIEQEVLTTWPADAIARAED
                     VVLCLSGMIEAVRPDTDITEVAKNNTLTDDDFSAGKSSTAS"
     gene            complement(8886..9638)
                     /locus_tag="IRB70_003701"
     CDS             complement(8886..9638)
                     /locus_tag="IRB70_003701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633564.1"
                     /translation="MATPNPLEPVKGAGTTLWVYNGKGDAYANPLSDDDWQRLAKVKD
                     LTPGEMTAESYDDNYLDDEDADWTATGQGQKSAGDTSFTLAWKPGEEGQKGLIGWFES
                     GDVRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGKPSVAEERSKITP
                     VSAIKVTPTSGTVAKGKTTTLTVSFEPESATDKTFRAVSADPSKATISVKDMTITVNG
                     VATGKVQIPVVSGNGQFAAVAEVTVTEAGAAG"
     gene            complement(9646..10041)
                     /locus_tag="IRB70_003702"
     CDS             complement(9646..10041)
                     /locus_tag="IRB70_003702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633565.1"
                     /translation="MKHTDIRAAVLDALEQHEHGATLFDGRPVVFDEEDFPAIAVYLT
                     DAEYTGEELDADTWRATLHIEVFLPAQVPDSELDQWMESRIYPAMTAIPALAGLITTM
                     VTQGYEYRRDDDMALWSSADLTYSITYEM"
     gene            complement(10038..10613)
                     /locus_tag="IRB70_003703"
     CDS             complement(10038..10613)
                     /locus_tag="IRB70_003703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633566.1"
                     /translation="MAIKGLDQAIDNLSRVRKNAIPAASAMTINRVAITAINQSSSQV
                     ARETRVRRKLVKERSRLKRATVRNPNARIIVNRGDLPVIKLGIRMLGRRPNSILKAGQ
                     HRYQRAFIQRLNNGRWHVMQRLPQARYEEGNDDKGRKKRNRLPIQVVKIPMAAPLKQA
                     FDENVDRIRRERLPKELAYALKQQLRIAIKR"
     gene            complement(10628..10981)
                     /locus_tag="IRB70_003704"
     CDS             complement(10628..10981)
                     /locus_tag="IRB70_003704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633567.1"
                     /translation="MRDFQNAFDAALAGVDSTIVEVMGLCAQFTSGAQCGSEVQGVFD
                     DPESLGFAGGGVRIEGSCPSLFVRTDTVRAVRRGDTLTINGETFWVDRVSPDDGGSCY
                     LWLNRGQPPAVNRRR"
     gene            complement(10974..11357)
                     /locus_tag="IRB70_003705"
     CDS             complement(10974..11357)
                     /locus_tag="IRB70_003705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001355131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HBC0633568.1"
                     /translation="MATKEENLNRLRQLAGLLGREADMSGSAADIAQRVSEWEEELAV
                     SPEGIMHSDESGADQNHTDDGEQLNNTDAPDDVKAVRVRKCLQVMGYCPETGRPVELA
                     LRGMRVLVPSSLATAMIQHGTAEYA"
     gene            complement(11409..12437)
                     /locus_tag="IRB70_003706"
     CDS             complement(11409..12437)
                     /locus_tag="IRB70_003706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HBC0633569.1"
                     /translation="MGLFTTRQLLGYTEQKVKFRALFLELFFRRTVNFHTEEVMLDKI
                     TGKTPVAAYVSPIVEGKVLRHRGGETRVLRPGYVKPKHEFNYQQAVERLPGEDPAQLN
                     DPAYRRLRIITDNLKQEEHAIVQVEEMQAVNAVLYGKYTMEGEQFDTVEVDFGRSEGN
                     NIEQADGKKWSEQDRDTFDPTHDIDLYCDQASGLVNIAIMDGTVWRLLNGFKLFREKL
                     DTRRGSNSQLETAVKDLGAVVSFKGYYGDLAIVVAKTSYVADDGTEKRYLPVGTLVLG
                     NTAAEGIRCYGAIQDAQALSEGVVASSRYPKHWLTVGDPAREFTMTQSAPLMVLPDPD
                     EFVVVQVK"
     gene            complement(12495..12842)
                     /locus_tag="IRB70_003707"
     CDS             complement(12495..12842)
                     /locus_tag="IRB70_003707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HBC0633570.1"
                     /translation="MVTKTITEQRAEVRIFAGNDPAHTATGSSGISSATPALTPLMLD
                     GATGKLVVWDGQKAGSAVGILVLPLEGTEAVLTYYKSGTFATEAIRWPESVDEHKKAN
                     AFTGSALSHAALP"
     gene            complement(12879..14384)
                     /locus_tag="IRB70_003708"
     CDS             complement(12879..14384)
                     /locus_tag="IRB70_003708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HBC0633571.1"
                     /translation="MRRNLSHIIAAAFNEPLLLEPAYARVFFCALGREMGAASLSVPQ
                     QQVQLDAPGMLAETDEYMAGGKRPARVYRVVNGIAVLPVTGTLVHRLGGMRPFSGMTG
                     YDGIVACLQQAMADSQVRGILLDIDSPGGQAAGAFDCADMIYRLRQQKPVWALCNDTA
                     CSAAMLLASACSRRLVTQTSRIGSIGVMMSHVSYAGHLAQAGVDITLIYSGAHKVDGN
                     QFEALPAEVRQDMQQRIDAARRMFAEKVAMFTGLSIDAVTGTEAAVFEGQSGIEAGLA
                     DELINASDAISVMATALNSNVRGGTMPQLTATEAAVQENQRVMGILTCQEAKGREQLA
                     TMLAGQQGMSVEQARAILAAAAPQQPVASAQSEADRIMACEEANGREQLAATLAAMPE
                     MTVEKARPILAAAPLADAGPSLRDQIMALDEAKGAEAQAEKLAACPGMTVESARAVLA
                     AGSGKAEPVSASTTALFEHFMANHSPAAVQGGVSQASEDGDADVKMLMAMP"
     gene            complement(14374..15966)
                     /locus_tag="IRB70_003709"
     CDS             complement(14374..15966)
                     /locus_tag="IRB70_003709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBC0633572.1"
                     /translation="MKRTPVLIDVNGVPLRESLSYTGGGAGFGGQMAEWLPPSQSADA
                     ALLPALRLGNARADDLVRNNGIAANAVALHKDHIVGHMFLISYRPNWRWLGMRETAAK
                     SFVDEVEAAWSEYAEGMFGEIDVEGKRTFTEFIREGVGVHAFNGEIFVQPVWDTESTQ
                     LFRTRFKAVSPKRVDTPGHGIGNRFLRAGVEVDRYGRAVAYHICEDDFPRSGSGRWER
                     IPRELPTGRPAMLHIFEPVEDGQTRGANQFYSVMERLKMLDSLQATQLQSAIVKAMYA
                     ATIESDLDTEKAFEYIAGAPQGQKDNPLINILDKFSTWYDTNSVTLGGVKIPHLFPGD
                     DLKLQTAQDSDNGFSALEQALLRYIAAGLGVSYEQLSRDYSKVSYSSARASANESWRY
                     FMGRRKFIASRLATQMFSCWLEEALLRGIIRPPRARFDFYQARSAWSRAEWIGAGRMA
                     IDGLKEVQESVMRIEAGLSTYEKELALMGEDYQDIFRQQVRESAEREKAGLSRPVWIA
                     QAYQQQIAESRRPEEETTPRET"
     gene            complement(15963..16169)
                     /locus_tag="IRB70_003710"
     CDS             complement(15963..16169)
                     /locus_tag="IRB70_003710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633573.1"
                     /translation="MVTVAELQALRQARLDLLTGKRVVSVQKDGRRIEYTAASLDELN
                     RAINDAESVLGTTRRRRRPLGVRL"
     gene            complement(16153..18081)
                     /locus_tag="IRB70_003711"
     CDS             complement(16153..18081)
                     /locus_tag="IRB70_003711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HBC0633574.1"
                     /translation="MISDAQKAANAAGAIATGLLSLIIPVPLTTVQWANKHYYLPKES
                     SYTPGRWETLPFQVGIMNCMGNDLIRTVNLIKSARVGYTKMLLGVEAYFIEHKSRNSL
                     LFQPTDSAAEDFMKSHVEPTIRDVPALLELAPWFGRKHRDNTLTLKRFSSGVGFWCLG
                     GAAAKNYREKSVDVVCYDELSSFEPDVEKEGSPTLLGDKRIEGSVWPKSIRGSTPKIK
                     GSCQIEKAANESAHFMRFYVPCPHCGEEQYLKFGDDASPFGLKWEKNKPESVFYLCEH
                     HGCVIHQSELDQSNGRWICENTGMWTRDGLTFFSAADNEIPPPRSITFHIWTAYSPFT
                     TWVQIVYDWLDALKDPNGLKTFVNTTLGETWEEAVGEKLDHQVLMDKVVRYTAAVPSR
                     VVYLTAGIDSQRNRFEMYVWGWAPGEEAFLVDKIIIMGRPDEEETLLRVDVAINKKYR
                     HADGTEMTISRVCWDTGGIDGEIVYQRSKKHGVFRVLPVKGASVYGKPVITMPKTRNQ
                     RGVYLCEVGTDTAKEILYARMKADPTPADEATSYAIRFPDDPEIFSQTEAQQLVAEEL
                     VEKWEKGKMRLLWDNKKRRNEALDCLVYAYAALRVSVQRWQLDLAVLAKSREEETTRP
                     TLKELAAKLSGGVNGYSR"
     gene            complement(18053..18601)
                     /locus_tag="IRB70_003712"
     CDS             complement(18053..18601)
                     /locus_tag="IRB70_003712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000867575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBC0633575.1"
                     /translation="MKVNKKRLAEIFNVDPRTIERWQSQGLPCVSKGSKGIESVFDTA
                     MAIQWYAQRETDIENEKLRKELADLRAAAESDLQPGTIDYERYRLTKAQADAQELKNA
                     REDGVVLETELFTFILQRVAQEISGILVRVPLTLQRKYPDISPSHLDVVKTEIAKASN
                     VAAKAGENVGGWIDDFRRTEGS"
     gene            19012..20079
                     /locus_tag="IRB70_003713"
     CDS             19012..20079
                     /locus_tag="IRB70_003713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001383880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta family protein"
                     /protein_id="HBC0633576.1"
                     /translation="MSQHQYYPQLKWKPAEYESLMLLDQTTLSGFTPIITIPDIDWDY
                     ENECYKKSLSSYLSDFGINLAASWKANRPVLLDVKYLDKHGSSRHHPLDMCIQDARVN
                     GKEIIPVVSPAYSTNYIHAVQRNLINGLAISITPQTWHQFTSLVNHLNIHPSLIDVII
                     DFGDIQNATDSLKQQALSMVNTLSGQAPWRNLILSSTAYPASQAGIPQHQVHHIPRHE
                     YDLWMHVVQNFSNGRTPSFSDYPTASSTITSVDPRFMSQYVSVRYSNDTSWIFVKGTA
                     VKGNGWGQTKNLCTTLVSSPEYQVFGSKFSWGDDYIYQRSLGANKSGGSKEWRKVAHT
                     HHITLVVKQLYWLAQTQPAKP"
     gene            complement(20021..20641)
                     /locus_tag="IRB70_003714"
     CDS             complement(20021..20641)
                     /locus_tag="IRB70_003714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000654791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7726 family protein"
                     /protein_id="HBC0633577.1"
                     /translation="MKDQDVRFAVHHKLLKESHLDPDCLVVDEFSISLGASRADIAVI
                     NGVIHGYELKSEYDSLERLPLQIKHYSSVMDKVTLVVAEKHLEGALKLIPGWWGVKTV
                     SVGPKGAILIKHMRGEKLNRNHDTLMLAQLLWKDECIDVLERWGYSKGIKSKPRFELW
                     NIIAENIPIANLRLEVRTALKKRVGWKVKAWQAESAPTNKAVSRLT"
     gene            complement(21058..>21197)
                     /locus_tag="IRB70_003715"
     CDS             complement(21058..>21197)
                     /locus_tag="IRB70_003715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001492874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HBC0633578.1"
                     /translation="GMGDGESPGLTADAELNYYRLRSGIDKITAQVNYLQEYIRTQCL
                     K"
BASE COUNT         4648 a         6518 c         5003 g         5028 t
ORIGIN      
        1 cctgctggcg tattctcaat accggcaccg atacccgcaa tataaaggcg tccgtcctgc
       61 atctgctgca gtttcacggc ccacatgctg ttcaggttat tatttgtatc aacctgaact
      121 ttctgtatct gctggattgc cgcactctga ttttccagtt ttttattgac ggtctgcgtg
      181 atttcattgc tgacattcgt aatggacgtc ctgatttcag ccaggtccgg cgcaagctga
      241 ccgttatcaa tctgcgtcca cagctcctgg gccagatgtg ttttcccgat ttctcctttg
      301 aaaaaatcca ggtaaccttc cgcatcatcg ctcgcccgac cgacagcctc cacgaatgcc
      361 gatttgccaa cagtattcac actgcggata taaaaataat aatcatggcc cggtttgata
      421 ttgatactgg cagctatcca gtacagcgcc gagccaagat agcgggctgc ggtttcaacc
      481 tgcctgatat ccgcaatccg cttttccgag aaccagaact caaactgtac cgtcgggtca
      541 taaacggcaa gatgtggcgt tgcggttatc tgaaaatagc ccggcgtcag ctcaatccgc
      601 gacggtgctg ccggtgcggt aatccggaag gtggtggtgg caggttcacc ctgctggcca
      661 tagctgttta tcgcccgcac cgtcagggtg tattccccga gcggcaggcc gctgaaacgg
      721 tgctccgtgt ctgcggtgat ggcggtggtc accagtctgg catccgttcc cttaccactg
      781 gtcaggcgca gactgaagcg cacacccttc accacccgcg gcgtgtccca tttcgcctgc
      841 gccagatact ggccgtcagc tgcgctcacc tccaccgtca ggtgctgcac tgccggtggg
      901 atgacgctgt tcagggaacc tgactgcggc tcaaagcggg caccgttatc cacgatggct
      961 tctttttccg gtacgtgctg caccgccgtg atggcaaagg tgccgtccgt gttttcccgg
     1021 acggagacac agcggaacag acgacggcgc agtgacggca gggagagtcc ccacaccccg
     1081 tatgtctcca caccatcagg cagggtactg acctgtatcc ggtccggcgc ggggtgttcg
     1141 gtgatgtcca cactcaccgg cttaccgctg ccgttaatca ggttcaccgt ggcggcaccg
     1201 gtctccggaa gtgtcacttc acggtccagc gtcagggtgc gggtggcagc atcaatggac
     1261 aggacacgtc cgccggtcag ggtcccggca tagtcgttat cacagatttc aatgatgtca
     1321 ccgggtgtgt gccgcagccc ctgagacccg agcgtgaaat ccaccgtctg cgtttccagc
     1381 agttcggtct ttatcaccca cagtccggca cggtgggcct gaccgcggct ggtacagccg
     1441 aacgcgtcca tcttcagcag gttgcgtccg tagcgcagta tggcttccgg gtcttccacc
     1501 agttccgtgg aggtctgcca gccgttctgc gggtcggtgt aattcacctc caccgccgtg
     1561 tgccggtcct tcagggcact gaagctgtag cggaatccca cgccgttatc atccaccacc
     1621 acatcgctgt tggtgtacgg ccacaccaca tccgacgggc ggtcctgaac gaacgtcagc
     1681 gtctgaccgt tccataccgg catacagcgc atcgcagagc agaaatcact gagaacgtcc
     1741 cacgccttac gctgttgtgc caggtacgca ttaaaggtca tccgcggctc ggtccccccg
     1801 aaaccatccg ggaccgtctg gtcgcagtac tgcccgatgg catacagcgc ccacttgtcc
     1861 acatccgccg cccccagacg ttttcccatg ccgtagcgcg ggtgagtcag catgtcccac
     1921 aggcaccagg ccgggttgtt gctgtatgcc ggtttcagac tgccgtccca gataccactg
     1981 tacgtgcgtt tttccgggtc atagtttgac ggcacctgga tgatgcgacc gcggatatgg
     2041 tagttcaccg tcatctgctg gccgccgaac tgctccgcat ccacctgcag ccccacaatg
     2101 gccgtgttcg ggtagcactg tttcacatcg atgatttcgg tgtatgacga ccacagcgtc
     2161 ttattctgca gctggtccgt ggtgctgtcc gccgtctccc tgaccatccg gatgttaaag
     2221 ggccggggag gcagattatc cagaatcacc gaggccagga actgtgaggt ggtcttgccg
     2281 ttaatggtga cgtccttttc tgtcacccag ttaccgttac gctgtaactg aatcagcagg
     2341 cggacggatg ccgggttacg gtcacccttt gaggtggtct ccaccagtga ctgcaccccg
     2401 aaggtaaccc gcaggcggtc aatgttcgcg gacgtaatgg tgcgcgtcac cggttttgcc
     2461 ttcgtcactt ccacgcccag tccggtttca gctccggagg actcaaagcc ttccggtggt
     2521 gtctgctcct gctccccggc gcgccagacc gccgtcacac cgtgtatcac gggattgccg
     2581 tccgtgtccg tcagtggggt tttgttcacc agaatactct gcagtccctt caccggacct
     2641 tctatcggtc cctcaccaat cgcatcaatc acactcatca tctgcgtgga tttgagatta
     2701 tccttcgcct cacgaggcgt gtgtgcctta ccgccacctt ttcccataca gccttcccct
     2761 gaataaatta accgccactt gccattccgt acagaagtcg gatatccttc gcccgaaaag
     2821 catgaaacac atttctgcca tgctaaagag aaaccccggt atcagcagat accggggttt
     2881 tctttcatgc ccaccgataa tcctgttggt taaaaccggt aatggcataa aaattctgaa
     2941 tatcttcaca ttttcacaaa ctgactgtgg cgcgtataat ttctctgcgt taattttttt
     3001 gtcgtgatat aagaataatt ccttacactt aatcttcgta actctcccgc agttcctgtc
     3061 cgcgatcact gcgggatttt tttattcttt ttacccctgc cgcccgataa ccacgacctt
     3121 tccgcccccg ccttcatcac gggtactgat gtcctgggat atacggcggg agccaaccag
     3181 catttccccg taaggcaccg gcatcgggtt accctgggca atcatgttat ccagggagga
     3241 aaagtacgtg ttctgtttac cgttatccgt gcttttgtac tccggtgttt ttgccttcgg
     3301 ggccagcatc tgggccacac cgcccagtat catgctggcc cccagtgaaa acagcatcgt
     3361 ggtggcagaa aaaccgccgg cactcagggc tgtaccccat aacgccatcg aggcaccggc
     3421 agtgaagaaa gagcccacga tggctgccgc ccccagcaca atctgcagtc caccctttcc
     3481 ggccccggcc agtcgcggca caatatggat gaccgttccc tcacccagct gttcgtgaag
     3541 acgggcgtac accgcctccg gtgccgtgtc ataaccggca atacgtatct ggtaccagcc
     3601 ttcgttcatc tgacggcgaa agcccggcac ctgtaacgac agcgcccgga tggcttccgc
     3661 tgccgtgttc acatacaggc tgaggcggcg gccaaatcgt tgtaaatccc cgtgaaggca
     3721 gatgcgtgcc agtggcggtg acgccagaca gaatgcgttc gtcgttgcca tttttcggaa
     3781 tacctctccc gtttactcag ttgttcaggc agatggtgaa gaagctcacc gttgccgcag
     3841 taaatggcgg catggttcgg taccgaagca ccaaagcagc acagcagaat atcgcccgcc
     3901 tgtgcagagg acaggggcac ccggtaaaag ccggtgaccg ccatattgtc caggtaaagg
     3961 ttctgaccgt tgcgccacca gtcatcctcg cgatgaaaat ccggcatttc agtccccgcc
     4021 agatgataag catcccggaa cagcgtgtaa cagtccgtca ccccgtgctc aaagcgccgt
     4081 cctgtcagat gtggcacaca gcggaatttg tgaatgtcac cccggcagac cagccaccag
     4141 ggcagtgcgc tttttatctg cagccgccgg tcagcctcgc tcagccaggg cagcccaccg
     4201 ggatgactgt ggaccagtgc cacaatctcc ccctgcatct ctgcccgcag ccagtcttcc
     4261 ggtgcgatac gaaaatacgc ctccggctct gcagaaatat tcacacaagg gatataccac
     4321 tccccctccg gcgtgcttat cacgaagccg cacgactccg caggcgcaca ccgccgggca
     4381 tgcgccagaa tcgctgattc agtctgtgtc ataaaccggg atttactgcg aaagtttatt
     4441 aatggaaagg aaaccgccaa aattgccgac attcctgcgc agttcacacc cgcgcatgca
     4501 cttgctgcat ctgtccttac ggatatccgt ggtggggttg tcgaactcat ccgccaccgc
     4561 aggaccgtta tacccgcatt catctccccg gtaatcccac atacaggtgt tcgccagcat
     4621 gatgcgaccg ggaaacagcg ccccgtccgt ctcggtcggt gtagccagca caaacgaggc
     4681 cgtcatggct gtcagctgcg acatctgctc caccacccag cggtcactca gctcctgctc
     4741 cgggtccgcc tccggattgc ccgcaacgaa attcaccgca tccagaaaac gggcatacac
     4801 ccggcggcgg accaccgtgg cccccaccag actctgcagg tcttccgcca tcccggtgac
     4861 cagaccgaac agattggaca ccgtcagcga cggtctggca ctgctgcccc ggccgttcat
     4921 ctcaaagccg ctgccgtcaa tcgggtatgc ctcatactta cgcccctgcc aggtgaccgg
     4981 ctcccctttt tcattcagct cattacagaa aaaataccgc tcaccaccct gtaccgtcag
     5041 gtcgatttcc cagagtacca cccgcggtga ctgctctgac ttaaccgact cgttcagact
     5101 ttcttctcga atatcctgca tcagttcacc acctgcttaa actccgcgct gaactcaacg
     5161 cgcaacatcc cgacccgcgc agaccacccg gcacaggtca cctttatctg ccggtatgca
     5221 tagggtggct tccacaaaaa tgccttccag ccaccgtgct ctgccaggaa cgcttccaga
     5281 tgccgggcct cctcccgggt cacggaaagc gtcaccctgt atgttttcag gtcagcattc
     5341 agccctgccg ccatacgctg tgagtacccg tcaccaaaac gcacttcacg caccgatggc
     5401 tgcgagttca cctccatatc cggcttcact ttccagcgaa aggttttcat ccaccgctcc
     5461 ctgataacat accgccatca cgcaactgca gccggagttc atcctgtgcc cccttgcggg
     5521 ccatctcata caccgctttc atcagctgcg gccctgcccg cccgttgggg ccgtcgttct
     5581 gaatcaccac gtgattgttc tgattaaaat taatgccttc cgcccgccgc atctgcgccg
     5641 gacttccggc accgccgaca taaccacctt ccgcatagcc ccgcatcagg cggtacagat
     5701 tgccgacacc aatccggctg gtcgcctcct tcgtgaagac aaactccccg cgatgaacaa
     5761 tccccgcagg ttcatattta ccccccgtcc ccgtaaatcc cccggtcgcg aaatggaagt
     5821 tcgccgccgc agcctgaatg gctgtaccgc ctgacgcgga tgcgccgcca ccaacagccc
     5881 cgccaatggc gctgccgata ctcccgacta tccccaccat cgcctgcttc agaaaaatct
     5941 ctgtcagcat ggacagcaca gaacgggtga aaccacgcca gttctgttcg ctgccggtca
     6001 gcatcgctgc catattctgt gcaataccgt caaaggtctg cgtggccgcg tttttaacct
     6061 gcgaaaaact gtccgtcgca ctttccgccc actcgcccca gccggacttc atcccggcca
     6121 tccagcttcc acgaagctgc tcctccgcag accaggtgtt cttcagtgca gatgtggcct
     6181 tcgccagcgc agccggatta tcaccgtaca cctcacgaag gcgctgctct tccgactccc
     6241 gctgcgcctg acggtcggtg agtccgcggg cttttgcgct gattgccgcc tgcttcgcgc
     6301 tctgctgctg ttcaaaccgc gccgcctgct gtgccagctc attcagccgt ttctggtgtt
     6361 caatcttgtc gcccagctca gccagctggc gtttgtactc cagcgtctct ttctcatggg
     6421 ccagcaggga tttttcctgc tcagataact gccgtttcgt ggcggcctct ttcaggacca
     6481 catactgatt ttccgcttcc cataaatccc ggcgctgctg gctgattttc tcattcacac
     6541 cgctgtgttt ttccagcgtc ctgagctcgg tttcaagcgc cagcagggct gcatgcgcct
     6601 ggtcttcctg gcgctcaccg gcagacacct tcacaccgga cggctttttc tgcgtcgact
     6661 cataatcctt ttttgccgac gccatcagcg tgttgtaatc cgcctgcagg attttcccgt
     6721 ctttcagggc cttattcagc tcttcctgcc gggcggtata tttctccagt ggcgtcagca
     6781 ggcgctcata cgccttctgc gcctctccgg tatacttcag ctgtgacgac tcacgctcag
     6841 ccctgtccct tgccgccagt tcaccggctt tttccatatc cgactgcagc gttgccgctg
     6901 ccagacccag acgggcattt tcccggtcat cccatgcgcc ctgaaggttg gcccggaaag
     6961 aggaggtttt accgcggcgc tggctccggc tctggtacca ctgccatttt ttatccgcct
     7021 catcaaatgc cttctgcgca ctggcgagca tatccgctga ggattccgga cgaccgatat
     7081 ccagaatggc atcccacatc gatttgaatg ccttccctgt tttatccgcc caggtctcca
     7141 gtgttcccat gttttctttc aggcgacggg tctgctcatc aaagcctttc gtggcgatat
     7201 cgttcgccgc ctgcaatgcc ccggcctcgt ctccggaacg ctgcagctgt gcaacatacg
     7261 caatctgctc tgccgtcacg ttacggaact ggcgcgccat cgccatcagt cccgacgtcg
     7321 ggtcagtggt cagcttcccg aaggcttcag cgactttatc cacctccaca ccggatgcag
     7381 acgcaaaacg cgcgacactc tggttgatgg catcaaactg ttcaccacca cgcacaccgg
     7441 cattcaccag ggctgccagt gactctctcg cctggttaaa cgtcagccct gctgcctgcc
     7501 cggctcttga gagagtcagc atacgatcgg cagtcagtcc ggactgatta ccggaaagaa
     7561 ccagggtttt attaaacgct gaaagcgtgg aatctccctg gtaccaggcg tacaccagcg
     7621 cacctgtcgc caccgccagc gaggtgaccc cgaccatcgg cagggtgatc gcaccggcaa
     7681 gccccctgaa catggggatc atcccgccga aggagtcctt cacctgaccg ccctgttgca
     7741 gcaggatcag ccagggattc tgaccacctg caagctgcgt ggcgatatcc gtaaactgtg
     7801 cgggcagggt tcgcatggcc gctttatact gcccgacgga aatcccggct ttttgtgcag
     7861 ccagcgcctg gcggctcagg ccctgttcaa cagcactggc ggtttttctg gcgtcggtat
     7921 ccagacctga aaaatgacgc cttacccggc tcatctgctc atcgaaacgg acagcatcca
     7981 gactcaggtc aataacaaga tcaccaaccg gctgggacat atctcacacc tcccggaatc
     8041 cccgctgaag ccatcattaa tgcggcatca tccaccatga catccgccac atccgcagac
     8101 gataaaatat cgcgccctcc gtccccaccg aaccggacgc ctccggcaag tcctgccgct
     8161 ttctgcatca gcattttgtc ctcatccggc ctctccacct gctcttcctc atgccggggg
     8221 acaagcagac tgaaatcaga gggatgcata tccggatcgc aaaaaaacag gctgagtaca
     8281 gcgtacgtca gcccggaaaa atgcatatcc agctgggtat cctgaaaata atgcgtgcgg
     8341 taaaaacggt gccagtcggc atattcggtg gatgtcatcc cggcaagcat ggcgcgccag
     8401 tcgggtctcc ccatctcacg cgccagtctg agggcaaagt tcagctcgcc gtcgaagact
     8461 ttcccgcaga aaaatcatca tcagtcagcg tgttattttt cgccacttca gtaatatcag
     8521 tatccggacg aacagcttcg atcatcccgg acaggcacaa caccacgtct tccgcccggg
     8581 caatggcatc ggcaggccag gtggtgagca cttcctgctc tatcttcatc acggcctcat
     8641 tcattgacgg tgactgcgtt ttctgtggat ggttatgcca cagggacatc gccaccagaa
     8701 acgcgccggt tctgacgaga tcttccacgc ttacctgcag gttgccgcag gattctgcct
     8761 gttctgcacg ccgtttcagg agggcaagat gctcgatacg ctgcagcgca gacaattcgg
     8821 aaagcgtgac agacacaccg ttatattcaa attgttctgt tttcagaaac atgtattacc
     8881 tccgtttacc ctgcagcgcc cgcttcagta acggtgactt cagccactgc ggcgaactga
     8941 ccatttccgc tcaccacagg gatctgcacc ttacctgtcg ccacgccgtt taccgtaatt
     9001 gtcatatctt tcacactaat ggtggctttc gacggatcgg cggaaaccgc tctgaacgtc
     9061 ttgtcggttg cactttccgg ctcaaaagaa accgtcaggg tggttgtttt cccttttgcc
     9121 accgtaccgg atgtcggcgt caccttaatc gcactgaccg gcgtaatttt gctgcgttct
     9181 tccgctacag aaggtttacc cacgttagtg actttcaccg tgcgggtgat cacttctttc
     9241 gccgtcacgg ccttaccgat actgctgacc cagccacgaa acacatccac cgtgccattc
     9301 ggaaaacgga ttttataggc ccggacatcg ccgctttcaa accagcctat aagccctttc
     9361 tggccttcct ctcccggttt ccaggccagc gtaaaactgg tatcacctgc agatttctgc
     9421 ccctgcccgg tcgcggtcca gtccgcgtct tcatcatcca ggtagttatc atcgtaggat
     9481 tctgccgtca tctcgcccgg cgtcagatcc ttcaccttag ccagtcgctg ccagtcatcg
     9541 tctgacaacg ggtttgcata agcatcaccc ttgccgttgt aaacccacag agtggtaccg
     9601 gcacctttta ccggctcaag gggatttggt gttgccatat cgtcctcaca tctcgtatgt
     9661 aatggaataa gtcagatctg cagaactcca taacgccata tcgtcatcac gacgatactc
     9721 atagccctgc gtaaccatcg tggtaatcag tcctgccagt gccgggatcg cggtcatcgc
     9781 cgggtaaatc cggctttcca tccactgatc aagctctgaa tccggtacct gtgccggtaa
     9841 aaacacctca atgtgcagcg tggcccgcca ggtatctgca tccagctctt caccggtata
     9901 ctctgcatcc gtcagataaa ccgcgatcgc aggaaaatcc tcttcgtcaa aaacaacggg
     9961 gcgaccatca aacagcgtcg ccccgtgttc atgctgctcg agtgcatcca gcactgcggc
    10021 acgaatgtca gtgtgtttca tcgttttatc gcaatcctca gttgttgttt cagcgcgtat
    10081 gccagttctt taggcaggcg ttcacgccgg atacggtcaa cattctcatc aaatgcctgt
    10141 ttcagtgggg ccgccatcgg gattttcacc acctgaatgg gaaggcgatt acgctttttc
    10201 cttcccttgt cgtcattgcc ctcctcatat ctggcctggg gaagacgttg cataacatgc
    10261 cagcgcccat tatttaatcg ctggataaat gcccgctgat aacgatgctg accggctttg
    10321 agtatgctgt tcggacgacg ccccagcatt ctgatcccca gcttaatcac agggagatca
    10381 ccgcggttaa cgataattct ggcattcgga tttctgaccg tcgcccgttt cagtctggac
    10441 cgttccttta ccagtttccg tctcaccctg gtttcccggg caacctgtga cgaagactga
    10501 ttaatcgccg ttatggccac gcggttaatg gtcattgcag aagcagccgg aatggcgttt
    10561 ttacgaaccc ggctcagatt gtcaatcgcc tgatcaagcc cttttatcgc cataattcac
    10621 cctgcgttta tcgtcgccgg ttaactgcgg gtggttgccc acggttgagc cagagataac
    10681 agctgccccc gtcatccgga gaaacacgat ccacccagaa tgtctcacca ttaatggtca
    10741 gcgtgtcacc acgccgcacg gcacgaaccg tatccgtccg cacaaataat gacgggcagc
    10801 ttccttcaat acggaccccg ccaccggcaa accccagcga ctccggatcg tcaaaaaccc
    10861 cctgaacttc gctgccacac tgtgcccccg aggtgaactg cgcacagagt cccatcactt
    10921 caacgatcgt actgtctacc ccggcgaggg cagcatcaaa ggcattctga aaatcacgca
    10981 tattcagccg ttccgtgctg tatcatggcc gttgccagtg atgatggcac cagaacacgc
    11041 ataccccgta acgccagctc aacgggacga cctgtctccg ggcaataccc cattacttgc
    11101 aggcacttcc gtacccggac ggctttaaca tcatccggag catccgtgtt gttcaactgc
    11161 tcaccatcgt ctgtgtgatt ttgatcagcc ccgctctcat cagagtgcat aatgccctcc
    11221 ggggaaacag caagctcctc ttcccactca gacacacgtt gcgcaatatc cgcagcactc
    11281 cccgacatat ccgcctcgcg ccccagcagg ccagccagtt gacgaagacg attcagattt
    11341 tcttcttttg ttgccatctc agcctcctgt gaaaaaagac acgggggcat ttcgcccccg
    11401 ctcacggatt atttcacctg caccaccaca aactcatccg gatccggcag caccatcagc
    11461 ggtgcggact gcgtcatggt gaattcacgg gccggatcgc ccacagtcag ccagtgtttc
    11521 ggataacggg aagaggccac cacaccttcg gacaacgcct gcgcatcctg aatggcacca
    11581 tagcaacgaa tgccctctgc tgccgtattc cccaggacca gtgtgcccac cggcagataa
    11641 cgtttttcgg taccgtcgtc tgccacataa gacgttttcg ccaccacaat ggccagatca
    11701 ccgtaatacc ctttgaaaga caccaccgct cccaggtctt tcactgccgt ttcgagttgt
    11761 gaatttgagc cgcgacgggt atccagtttt tcgcggaaca gcttaaagcc attcagcaga
    11821 cgccagaccg taccgtccat aatggcaata ttcacaagac cgctggcctg atcgcagtaa
    11881 aggtcaatat catgcgtcgg atcaaacgta tcacggtcct gctcagacca ttttttaccg
    11941 tcggcctgct caatgttatt tccttcagag cgtccgaaat ccacctcgac cgtgtcaaac
    12001 tgttcccctt ccatggtgta tttgccatac agcacggcat tcaccgcctg catttcttcc
    12061 acctggacaa tggcgtgctc ttcctgtttg aggttatcgg taatgatacg cagacgacgg
    12121 taggccgggt cgttcagctg agccggatct tcaccaggaa ggcgctcaac cgcctgctgg
    12181 taattaaatt cgtgtttggg cttgacgtag cccggacgta acacgcgggt ttcaccaccg
    12241 cgatggcgaa gcacttttcc ttcaacgatc ggggagacat aggccgccac cggcgttttt
    12301 ccggtaattt tgtccagcat cacctcttcg gtgtggaaat tcaccgtacg gcggaaaaac
    12361 agctccagaa acagcgcacg gaatttaact ttttgttcgg tataaccgag taactggcgg
    12421 gtcgtaaaca atcccataaa tcagttcctt tcattaagaa atcagtcagg ccaacgcggt
    12481 ggcctgataa cgtgttacgg cagcgccgcg tgactcaggg cactgccggt aaaggcgttg
    12541 gcctttttgt gttcatccac actttcaggc cagcggattg cctccgtcgc aaaggtcccc
    12601 gacttgtaat aggtcagcac cgcctctgtg ccttcaagcg gcagtaccag tatgccaacc
    12661 gcactaccgg ctttctgtcc gtcccagacc accagtttcc cggtggcccc atccagcatc
    12721 aggggtgtca gtgccggtgt tgccgaggaa atcccgctgc tgcctgtggc ggtgtgagcc
    12781 ggatcattac cggcaaaaat acgtacttcc gcacgctgtt cagtgatggt tttcgtcacc
    12841 atattgttaa aacctcgtat tgatgttcag cactgacttc atggcatggc catgagcatt
    12901 ttcacgtccg catcaccgtc ttctgacgcc tgtgacacgc ccccctggac cgcagccggt
    12961 gaatggttcg ccatgaaatg ttcaaacagg gcggttgtgg atgcagagac cggttctgcc
    13021 ttacctgatc ccgcagccag cacagcccgg gcgctctcca cggtcattcc cgggcaggcc
    13081 gccagttttt cagcctgcgc ttctgcccct tttgcctcat ccagggccat gatctgatca
    13141 cgaagtgagg gcccggcatc cgccagtggt gcagccgcca ggatcgggcg ggctttttcc
    13201 accgtcatct ccggcatcgc cgccagcgtt gccgccagtt gttcacgacc gttcgcttct
    13261 tcacacgcca taatgcgatc ggcttcactc tgcgcggatg ccaccggctg ctgcggtgcc
    13321 gccgcggcca gaatcgcccg ggcctgttca acgctcatgc cctgttgccc tgccagcatc
    13381 gtggcaagct gttcacgtcc tttcgcttcc tggcatgtca ggatccccat cactcgctgg
    13441 ttctcctgca cggcggcttc cgttgcagtt aattgcggca tagtgcctcc tctgacatta
    13501 ctgttcagcg ccgtggccat cacactgatg gcatccgacg cattgattaa ttcatccgcc
    13561 agcccggcct caatgccgga ctgaccttca aaaacagcgg cctctgttcc cgtgactgca
    13621 tcaatagaca gaccggtaaa catcgccact ttttcggcaa acatccggcg cgccgcatca
    13681 atccgctgct gcatgtcctg gcgaacctct gccggcaacg cttcaaactg attgccatcc
    13741 accttgtgcg cccctgagta aatcagcgtg atatccacac cggcctgcgc cagatgaccg
    13801 gcatagctga catggctcat catcacgcca atggaaccga tacgggatgt ctgggtaacc
    13861 agccgtcggg agcaggccga cgccagcagc atggccgcag aacaggccgt gtcattacac
    13921 agtgcccaga ccggcttctg ctgccggagg cggtaaatca tgtcagcgca gtcaaacgcg
    13981 ccggcggcct gcccgcccgg actgtcaatg tccagcagta tgccccgcac ctggctatct
    14041 gccattgcct gctgaagaca ggcgacaatg ccgtcatagc cagtcattcc ggaaaatggc
    14101 cgcatccccc ccagccggtg caccagcgtg ccggtcaccg gcagtaccgc aataccgttc
    14161 accacccggt aaacacgggc cggtcgttta cctccggcca tgtactcgtc cgtttcagcc
    14221 agcatcccgg gagcatcaag ctgtacctgc tgttgcggta ccgaaagact tgctgccccc
    14281 atctcgcgcc ccagcgcgca aaagaaaacc cgcgcatagg cgggctccag aagcagcggt
    14341 tcattgaatg ctgctgcaat aatgtgtgaa agattacgtc tcacgtggtg ttgtctcctc
    14401 ttccggcctg cgactctccg ctatctgctg ctgatacgcc tgcgctatcc acaccggacg
    14461 tgagagtccg gctttttccc gctctgcaga ttccctgacc tgctggcgga aaatgtcctg
    14521 ataatcctcg cccatcagcg ccagctcttt ctcatacgtg ctcagtccgg cctcaatgcg
    14581 catcactgat tcctgaacct ccttgagccc gtcaatggcc attcttccgg ctccaatcca
    14641 ctcagcccgt gaccaggctg atcgcgcctg ataaaaatca aaccgtgccc gtggcggacg
    14701 aataatcccc cgaagaagtg cctcttccag ccagcaggaa aacatctgcg tggccagccg
    14761 ggacgcaata aattttcgcc gccccataaa atagcgccac gactcattgg cggatgcgcg
    14821 ggcacttgag taactgacct tcgagtaatc acgggacaac tgttcgtagg aaacgccaag
    14881 accggcggcg atataccgca gcagcgcctg ttcaagcgcc gaaaatccat tgtctgaatc
    14941 ctgcgcggtc tgaagtttca gatcatcacc ggggaaaagg tgcggaattt tgacaccgcc
    15001 cagcgtcacg ctattcgtgt cataccaggt ggagaactta tccagaatat taataagcgg
    15061 attatccttc tgcccctgcg gcgcaccggc gatatattca aaggcctttt cggtatcaag
    15121 gtcactttca atcgtcgctg catacatcgc cttcactatg gccgactgaa gctgtgttgc
    15181 ctgcagggaa tccagcatct tcagccgttc cataacgctg taaaactgat tggctccacg
    15241 ggtctgcccg tcctccaccg gctcgaaaat atgcagcatg gccggacgcc cggtgggtag
    15301 ttcacgcggg atccgttccc atcgtccact cccggagcga ggaaaatcat cctcacagat
    15361 atggtacgca acggcacggc catatcgatc aacctccaca ccggcccgca gaaaacggtt
    15421 cccgataccg tgtcctggcg tgtccacccg tttcggactc acggctttaa aacgcgtacg
    15481 aaacagttgc gtactctccg tatcccagac cggctgcaca aagatttcgc cgttaaacgc
    15541 atgaacgccc acaccttcac ggataaattc cgtaaacgtg cgtttccctt ccacgtcgat
    15601 ctcaccaaac atcccttctg cgtattctga ccaggccgcc tccacctcat cgacaaaact
    15661 ttttgccgcg gtctcccgca tccccagcca gcgccagttc ggacggtagc taatcagaaa
    15721 catatgcccg acaatgtgat ccttatgcag ggccaccgca ttggccgcta ttccgttatt
    15781 gcgcaccaga tcatctgcac gggcattccc cagacgcaac gcgggcagca gggccgcatc
    15841 ggcactctgc gagggtggca accactctgc catttgcccg ccaaatcctg caccgccacc
    15901 ggtgtagctg aggctctccc gaagcggaac gccgttcaca tcaatcagga caggcgttcg
    15961 tttcataacc tcactcccag cggacgacgg cgacggcggg ttgtccccag taccgactcc
    16021 gcatcattga tcgcccggtt aagctcatcc agagaagctg ccgtatattc aattctgcga
    16081 ccatctttct gaacagacac cacccgttta ccggttaata aatcaaggcg cgcctgacgc
    16141 agcgcctgca gttcagcgac tgtaaccatt cactcctccg gacagcttcg ctgccagttc
    16201 tttaagggtt ggccgggtcg tctcttcttc ccgggatttt gccagtacag ccagatcaag
    16261 ctgccagcgt tgcacggaca cacgtaatgc cgcgtaggca tacaccaggc agtccagcgc
    16321 ttcgttacgc cgctttttgt tatcccacag cagacgcatc tttccttttt cccacttctc
    16381 cacaagctct tccgccacca gttgctgcgc ctctgtctgc gaaaaaatct ccggatcatc
    16441 aggaaaacgg atggcatacg acgtggcttc atccgcaggc gtgggatcgg ctttcatacg
    16501 ggcatagaga atttcttttg cggtgtccgt ccccacttcg cacagataca cgccccgctg
    16561 attgcgggtt tttggcatgg tgatcaccgg cttgccataa acagatgcac cttttaccgg
    16621 cagcacccgg aaaacaccgt gtttttttga cctctgatag acaatttcgc catcgatccc
    16681 cccggtgtcc cagcagacac gggaaatggt catttcggtt ccgtctgcat ggcggtattt
    16741 tttgttgatc gccacatcca cacgtaacag cgtctcttcc tcatcgggac gccccataat
    16801 gatgatttta tccaccagaa aggcttcctc tcccggagcc catccccaga catacatctc
    16861 aaaacggttt cgctgcgagt caatgcccgc cgtcagataa accacccggg aaggcaccgc
    16921 agccgtgtaa cgcacaacct tatccatcag cacctggtga tcgagttttt cgcccacggc
    16981 ctcttcccag gtctcgccca gcgtggtgtt cacaaaggtt ttcaggccgt tgggatcttt
    17041 cagtgcatcc agccagtcat agacaatctg tacccaggtg gtgaacggac tgtacgccgt
    17101 ccagatatgg aatgtgatgg agcgcggcgg cggaatttca ttatccgcgg cgctgaaaaa
    17161 tgtcagaccg tcacgagtcc acatgcccgt gttttcacag atccaccgcc cgttactctg
    17221 gtcaagctca gactgatgga tcacacagcc atgatgctca caaaggtaga aaacactttc
    17281 tggcttattc ttctcccact taagaccgaa aggcgaggca tcatcgccaa atttcagata
    17341 ctgctcctcc ccacagtgcg gacagggcac ataaaaacgc atgaaatgtg ccgactcgtt
    17401 agcggctttt tcgatctggc aggagccttt gattttaggc gtcgagccgc gaatggattt
    17461 tggccataca gagccctcaa tacgtttatc ccccagcagg gttggcgaac cctctttttc
    17521 aacatccggt tcgaacgagg aaagctcgtc ataacaaacc acatccacgg atttttcacg
    17581 gtagtttttt gctgccgctc cccccagaca ccagaaaccc acaccggagg aaaaacgctt
    17641 cagggtgagc gtattatcgc ggtgttttct tccgaaccat ggagccagct ccagcaatgc
    17701 aggaacatcc cttatcgttg gctcaacatg agatttcata aaatcttcag cagctgagtc
    17761 cgtgggctga aaaagaaggc tgttgcgtga tttatgctca ataaaataag cctccactcc
    17821 cagcaacatc tttgtataac caacacgggc agatttaatc aggttaacag tgcgaatcaa
    17881 atcgttgccc atacagttca tgatgccaac ctgaaacggc agtgtttccc accgccccgg
    17941 ggtataagac gactctttag gaaggtaata atgtttattg gcccactgaa ctgtcgtcag
    18001 tggaacagga ataatgagag ataaaagccc tgtagctatc gcaccggctg cattagctgc
    18061 cttctgtgcg tctgaaatca tcgatccacc cgcccacgtt ttcaccggcc ttagctgcaa
    18121 cattggaggc tttcgcgatt tcagttttca ccacatcaag gtgtgatggt gaaatgtccg
    18181 gatatttacg ctgtaatgtc aacggcacac gcacaagtat ccccgaaatc tcctgtgcca
    18241 cacgttgcag aataaaggta aacagttcag tttccagcac cactccgtct tcacgggcat
    18301 ttttcagttc ctgcgcatct gcctgcgctt ttgtgagccg gtagcgttca tagtcaatgg
    18361 tgccgggttg taaatctgac tccgctgccg cacgcaaatc ggccagttct ttgcggagct
    18421 tttcgttttc gatatcagtt tccctctgcg cataccactg aattgccatg gcagtatcaa
    18481 atacagattc aatgccctta ctgcctttgg agacgcaagg gagcccctga gactgccagc
    18541 gttcaatcgt ccgcgggtcc acgttaaaaa tttcggcaag cctcttttta ttaaccttca
    18601 tagaacaacc cattatcaaa tacaaggccc gacatgaaaa cgccagaaaa aggcattttc
    18661 ggacactttc atgtcggaca tttatgaatg caatattaaa aaaaacaaaa agttatattc
    18721 gagaagtacc gacacgattt tccctgaaaa attttcataa atagtgaaaa accgcgaggt
    18781 cgccgccccg taacggtctg gatcaccgga aaggacccgc caacgacttt cgcgtgcagg
    18841 cattaaaaat tttgcagttc catgcctagt tgaaacctcg atttctataa catccaattt
    18901 tgtaaattta gatatagctc aacttttcct aatgttttca agtgtataaa aacaattggc
    18961 gttacgccat aacactatac ttaggataag taaagatttt aaggagtttt aatgagtcaa
    19021 catcaatatt atccacagct gaaatggaag cctgctgaat atgaatctct gatgctttta
    19081 gatcaaacta cgctctctgg ttttactccg atcattacca ttccagacat agactgggat
    19141 tatgaaaacg aatgctacaa gaagagtttg agttcttact tatctgactt cggtattaac
    19201 cttgcggcat cctggaaagc caatcgtcct gttttgctgg atgttaaata tttagataaa
    19261 catggttcga gccgccatca tcctctagat atgtgtatcc aagatgctag agtaaatggt
    19321 aaggaaatta tccctgttgt ttctcccgca tattcaacaa actatataca tgctgttcaa
    19381 cgcaacttaa tcaatgggct cgctatatct atcacccccc agacatggca ccaattcaca
    19441 agtctggtta accacttaaa tattcatcct agtttaattg atgtaatcat tgattttgga
    19501 gatattcaaa acgcaactga tagtttaaaa caacaagcat taagcatggt caacacatta
    19561 tcaggccaag ctccgtggag aaacttgatt ttatcttcaa ccgcataccc agcatcacag
    19621 gcagggatac cgcaacatca agttcatcat attccgcgcc atgaatacga tctttggatg
    19681 cacgtagtac agaattttag caatggaaga acgccaagtt ttagtgatta tcccaccgct
    19741 agctctacca ttacgagcgt agacccacgc ttcatgtctc agtatgtctc agtgagatat
    19801 tcgaacgata cctcatggat ctttgtaaaa ggtaccgcag ttaaaggaaa tggatggggc
    19861 caaactaaaa acttatgtac tacccttgtt agttcgccag agtatcaagt ctttggttcc
    19921 aaatttagtt ggggggatga ttacatttac caaagatcat taggcgctaa caaatctggc
    19981 ggctctaaag aatggcgtaa agttgcacat acgcaccata ttacgttagt cgtgaaacag
    20041 ctttattggt tggcgcagac tcagcctgcc aagccttaac tttccagcct acgcgtttct
    20101 ttaaggctgt tctgacttca agcctgagat tcgctattgg aatattttcc gcaataatat
    20161 tccataactc aaatcggggc ttgcttttga ttcctttgga atagccccat cgttcaagta
    20221 cgtcgataca ttcatctttc caaagcaatt gagcgagcat caatgtgtca tggtttcgat
    20281 taagcttttc tccacgcatg tgctttataa gaatggcgcc ttttggccca acagaaaccg
    20341 ttttaacgcc ccaccaacct gggattaact ttaatgctcc ctcaagatgt ttctcagcta
    20401 cgacaagagt aaccttgtcc attacagaag aataatgctt gatttgaaga ggcaaacgct
    20461 ccaaagagtc atattcactt ttgagctcgt acccgtgtat aacaccattt attacagcaa
    20521 tgtctgctct actggcgcca agggatatgg aaaattcatc gaccacaagg cagtctggat
    20581 ctaaatgcga ttctttcaaa agcttatgat gcaccgcgaa cctaacatct tgatctttca
    20641 tgacttctcc ttactccctc cgttattgaa ttatagcgca ctgcatttta ctgcatttga
    20701 gagatttgac cacttcaatc acaaaatgct tatctgcagc aacaagattc atagccatac
    20761 gactatggtg attacctttt gtctggaaaa ctgaccattc cacgaagatc agataggtct
    20821 atagaatctt ggtttgtcat agcgttcgcc ttactttgag atgaaccttt gctgcatagg
    20881 agatcagccc gtcaaggctc accagcacta actgactact caaaggctca ttccaaaggg
    20941 tttggttcga cgtggttgag tgcgctgcgg tgcgcggtga aatacctgta caaaaatgcc
    21001 ccgcatctgc gaggcatttt cctgaaagtc acgtattaaa tttcagtgaa attaaaatta
    21061 ttttaagcac tgcgtcctga tgtactcctg caggtagttg acctgcgcgg ttatcttgtc
    21121 gattccactt cggagacggt aataattgag ttcagcatct gctgtaagtc ctgggctttc
    21181 tccatcgccc atgccgc
//
LOCUS       DADXDL010000088        21070 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.088, whole genome shotgun sequence.
ACCESSION   DADXDL010000088 DADXDL010000000
VERSION     DADXDL010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 21070)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21070)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21070
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.088"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            33..629
                     /locus_tag="IRB70_003716"
     CDS             33..629
                     /locus_tag="IRB70_003716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001683249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBC0633579.1"
                     /translation="MNNTDLIYLIKHFMHNELKAVEEVIDSPLSEFANLIKVLQSCQG
                     KVVFIGVGKSGIIARKLAATFASTGTPSFFVHGTEAVHGDLGMVAKDDVVILISNSGE
                     TAEILATLPSLKKMGNYLISFTRSHHSSLAISCDLSVEIPVKSEADNLGLAPSCSSTV
                     VLVVGDAVALALSELKKFTRADFGLYHPGGALGIKANS"
     gene            701..1648
                     /locus_tag="IRB70_003717"
     CDS             701..1648
                     /locus_tag="IRB70_003717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001361319.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBC0633580.1"
                     /translation="MKNVLVTVPSFSARCVSASKLLRENNFNLIIKNNVEHLLKSEST
                     ALRESICAVIAGKDCYQADTLSLLSGVKIISRFGTGIDNIDLRAAQQSGIIVNNAVGI
                     NSNAVAEFIIGLIFASMRNIPGSYHAMQNGYWGESHGCELQGKRIGLLGYGNIGKTLA
                     KRLSGFDVELLAFDKQPDYQVADKAGVQFVSIEDIFMQSHVIIVLLPFSSELENFISH
                     KYLSMMRNGALIINAARGKLLDEGALLQVIEERNVFAALDVFSSEPLAQFSPLLHAKN
                     IITTPHIAAATVESYQQTGIHVAQSIIDYFAGREIKNVL"
     gene            complement(1727..1803)
                     /locus_tag="IRB70_003718"
     tRNA            complement(1727..1803)
                     /locus_tag="IRB70_003718"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1767..1769),aa:Met,seq:cat)
     gene            2012..3109
                     /gene="mltA"
                     /locus_tag="IRB70_003719"
     CDS             2012..3109
                     /gene="mltA"
                     /locus_tag="IRB70_003719"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase A"
                     /protein_id="HBC0633581.1"
                     /translation="MKGRWVKYLLMGTVVAMLAACSSKPTDRGQQYKDGKFTQPFSLV
                     NQPDAVGAPINAGDFAEQINHIRNSSPRLYGNQSNVYNAVQEWLRAGGDTRNMRQFGI
                     DAWQMEGADNYGNVQFTGYYTPVIQARHTRQGEFQYPIYRMPPKRGRLPSRAEIYAGA
                     LSDKYILAYSNSLMDNFIMDVQGSGYIDFGDGSPLNFFSYAGKNGHAYRSIGKVLIDR
                     GEVKKEDMSMQAIRHWGETHSEAEVRELLEQNPSFVFFKPQSFAPVKGASAVPLVGRA
                     SVASDRSIIPPGTTLLAEVPLLDNNGKFNGQYELRLMVALDVGGAIKGQHFDIYQGIG
                     PEAGHRAGWYNHYGRVWVLKTAPGAGNVFSG"
     gene            3186..3992
                     /gene="tcdA"
                     /locus_tag="IRB70_003720"
     CDS             3186..3992
                     /gene="tcdA"
                     /locus_tag="IRB70_003720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA cyclic N6-threonylcarbamoyladenosine(37)
                     synthase TcdA"
                     /protein_id="HBC0633582.1"
                     /translation="MSVVISDAWRQRFGGTARLYGEKALQLFADAHICVVGIGGVGSW
                     AAEALARTGIGSITLIDMDDVCVTNTNRQIHALRDNVGLAKAEVMAERIRQINPECRV
                     TVVDDFVTPDNVAQYMSVGYSYVIDAIDSVRPKAALIAYCRRNKIPLVTTGGAGGQID
                     PTQIQVTDLAKTIQDPLAAKLRERLKSDFGIVKNSKGKLGVDCVFSTEALVYPQSDGT
                     VCAMKATAEGPKRMDCASGFGAATMVTATFGFVAVSHALKKMMAKAARQG"
     gene            complement(4043..4486)
                     /gene="csdE"
                     /locus_tag="IRB70_003721"
     CDS             complement(4043..4486)
                     /gene="csdE"
                     /locus_tag="IRB70_003721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase sulfur acceptor subunit
                     CsdE"
                     /protein_id="HBC0633583.1"
                     /translation="MTNPQFAGHPFGTTVTAETLRNTFAPLTQWEDKYRQLIMLGKQL
                     PALPDELKAQAKEIAGCENRVWLGYTVAENGKMHFFGDSEGRIVRGLLAVLLTAVEGK
                     TAAELQAQSPLALFDELGLRAQLSASRSQGLNALSEAIIAAAKQV"
     gene            complement(4486..5691)
                     /gene="csdA"
                     /locus_tag="IRB70_003722"
     CDS             complement(4486..5691)
                     /gene="csdA"
                     /locus_tag="IRB70_003722"
                     /EC_number="3.13.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase CsdA"
                     /protein_id="HBC0633584.1"
                     /translation="MNVFNPAQFRAQFPALQDAGVYLDSAATALKPEAVVEATRQFYS
                     LSAGNVHRSQFAEAQRLTARYEAAREKVAQLLNAPDDKNIVWTRGTTESINMVAQCYA
                     RPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAQVVKLPLNAQRLPDVDLLPELITPR
                     SRILALGQMSNVTGGCPDLAQAITFAHSAGMVVMVDGAQGAVHFPADVQQLDIDFYAF
                     SGHKLYGPTGIGVLYGKSELLEAMSPWLGGGKMIHEVSFDGFTTQSAPWKLEAGTPNV
                     AGVIGLSAALEWLADYDINQAESWSRSLATLAEDALAKRPGFRSFRCQDSSLLAFDFA
                     GVHHSDMVTLLAEYGIALRAGQHCAQPLLAELGVTGTLRASFAPYNTKSDVDALVNAV
                     DRALELLVD"
     gene            5883..6110
                     /locus_tag="IRB70_003723"
     CDS             5883..6110
                     /locus_tag="IRB70_003723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417289.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgdI/YgdR family lipoprotein"
                     /protein_id="HBC0633585.1"
                     /translation="MKKTAAIISACMLTFALSACSGSNYVMHTNDGRTIVSDGKPQTD
                     NDTGMISYKDANGNKQQINRTDVKEMVELDQ"
     gene            6461..7378
                     /gene="gcvA"
                     /locus_tag="IRB70_003724"
     CDS             6461..7378
                     /gene="gcvA"
                     /locus_tag="IRB70_003724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005130970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system transcriptional
                     regulator GcvA"
                     /protein_id="HBC0633586.1"
                     /translation="MSKRLPPLNALRVFDAAARHLSFTRAAEELFVTQAAVSHQIKSL
                     EDFLGLKLFRRRNRSLLLTEEGQSYFLDIKEIFSQLTEATRKLQARSAKGALTVSLLP
                     SFAIHWLVPRLSSFNSAYPGIDVRIQAVDRQEDKLADDVDVAIFYGRGNWPGLRVEKL
                     YAEYLLPVCSPLLLTGEKPLKTPEDLAKHTLLHDASRRDWQTYTRQLGLNHINVQQGP
                     IFSHSAMVLQAAIHGQGVALANNVMAQSEIEAGRLVCPFNDVLVSKNAFYLVCHDSQA
                     ELGKIAAFRQWILAKAAAEQEKFRFRYEQ"
     gene            7397..7792
                     /locus_tag="IRB70_003725"
     CDS             7397..7792
                     /locus_tag="IRB70_003725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF423 domain-containing protein"
                     /protein_id="HBC0633587.1"
                     /translation="MTSRFMLIFAAISGFIFVALGAFGAHVLSKTMGAVEMGWIQTGL
                     EYQAFHTLAILGLAVAMQRRISIWFYWSSVFLALGTVLFSGSLYCLALSHLRLWAFVT
                     PVGGVSFLAGWALMLVGAIRLKRKGVSHE"
     gene            7785..8885
                     /gene="rlmM"
                     /locus_tag="IRB70_003726"
     CDS             7785..8885
                     /gene="rlmM"
                     /locus_tag="IRB70_003726"
                     /EC_number="2.1.1.186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010435097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (cytidine(2498)-2'-O)-methyltransferase
                     RlmM"
                     /protein_id="HBC0633588.1"
                     /translation="MNKVVLLCRPGFEKECAAEITDKAGQREIFGFARVKENAGYVIY
                     ECYQPDDGDKLIRELPFSSLIFARQWFVVGELLQHLPPEDRITPIVGMLQGVVEKGGE
                     LRVEVADTNESKELLKFCRKFTVPLRAALRDAGVLANYETPKRPVVHVFFIAPGCCYT
                     GYSYSNNNSPFYMGIPRLKFPADAPSRSTLKLEEAFHVFIPADEWDERLANGMWAVDL
                     GACPGGWTYQLVKRNMWVYSVDNGPMAQSLMDTGQVTWLREDGFKFRPTRSNISWMVC
                     DMVEKPAKVAALMAQWLVNGWCRESIFNLKLPMKKRYEEVSHNLAYIQAQLDEHGINA
                     QIQARQLYHDREEVTVHVRRIWAAVGGRRDER"
     gene            complement(8929..9660)
                     /gene="fucR"
                     /locus_tag="IRB70_003727"
     CDS             complement(8929..9660)
                     /gene="fucR"
                     /locus_tag="IRB70_003727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose operon activator"
                     /protein_id="HBC0633589.1"
                     /translation="MKAARQQAIVDLLLNHTSLTTEALSEQLKVSKETIRRDLNELQT
                     QGKILRNHGRAKYIHRQNQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMVIALDAS
                     STCWYLARQLPDINIQVFTNSHPICHELGKRERIQLISSGGTLERKYGCYVNPSLISQ
                     LKSLEIDLFIFSCEGIDSSGALWDSNAINADYKSMLLKRAAQSLLLIDKSKFNRSGEA
                     RIGHLDEVTHIISDERQVATSLVTA"
     gene            complement(9718..10140)
                     /gene="fucU"
                     /locus_tag="IRB70_003728"
     CDS             complement(9718..10140)
                     /gene="fucU"
                     /locus_tag="IRB70_003728"
                     /EC_number="5.1.3.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose mutarotase"
                     /protein_id="HBC0633590.1"
                     /translation="MLKTISPLISPELLKVLAEMGHGDEIIFSDAHFPAHSMGPQVIR
                     ADGLLVSDLLQAIIPLFELDSYAPPLVMMAAVEGDTLDPEVERRYRNALSLQAPCPDI
                     IRINRFAFYERAQKAFAIVITGERAKYGNILLKKGVTP"
     gene            complement(10142..11560)
                     /gene="fucK"
                     /locus_tag="IRB70_003729"
     CDS             complement(10142..11560)
                     /gene="fucK"
                     /locus_tag="IRB70_003729"
                     /EC_number="2.7.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417283.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculokinase"
                     /protein_id="HBC0633591.1"
                     /translation="MKQEVILVLDCGATNVRAIAVNRQGKIVARASTPNASDIAMENN
                     TWHQWSLDAILQRFADCCRQINSELTDCHIRGIAVTTFGVDGALVDKQGNLLYPIISW
                     KCPRTAAVMDNIERLISAQQLQAISGVGAFSFNTLYKLVWLKENHPQLLERAHAWLFI
                     SSLINHRLTGEFTTDITMAGTSQMLDIQQRDFSPQILQATGIPRRLFPRLVEAGEQIG
                     TLQNSAAAMLGLSVGIPVISAGHDTQFALFGAGAEQNEPVLSSGTWEILMVRSAQVDT
                     SLLSQYAGSTCELDSQAGLYNPGMQWLASGVLEWVRKLFWTAETPWQMLIEEARLIAP
                     GADGVKMQCDLLSCQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLQMLEKIGHFKA
                     SELLLVGGGSRNTLWNQIKANMLDIPVKVLDDAETTVAGAALFGWYGVGEFNSPEEAR
                     AQIHYQYRYFYPQTEPEFIEEV"
     gene            complement(11669..13444)
                     /gene="fucI"
                     /locus_tag="IRB70_003730"
     CDS             complement(11669..13444)
                     /gene="fucI"
                     /locus_tag="IRB70_003730"
                     /EC_number="5.3.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose isomerase"
                     /protein_id="HBC0633592.1"
                     /translation="MKKISLPKIGIRPVIDGRRMGVRESLEEQTMNMAKATAALLTEK
                     LRHACGAAVECVISDTCIAGMAEAAACEEKFSSQNVGLTITVTPCWCYGSETIDMDPT
                     RPKAIWGFNGTERPGAVYLAAALAAHSQKGIPAFSIYGHDVQDADDTSIPADVEEKLL
                     RFARAGLAVASMKGKSYLSLGGVSMGIAGSIVDHNFFESWLGMKVQAVDMTELRRRID
                     QKIYDEAELEMALAWADKNFRYGEDENNKQYQRNAEQSRAVLRESLLMAMCIRDMMQG
                     NSKLADIGRVEESLGYNAIAAGFQGQRHWTDQYPNGDTAEALLNSSFDWNGVREPFVV
                     ATENDSLNGVAMLMGHQLTGTAQVFADVRTYWSPEAIERVTGHKLDGLAEHGIIHLIN
                     SGSAALDGSCKQRDSEGNPTMKPHWEISQQEADACLAATEWCPAIHEYFRGGGYSSRF
                     LTEGGVPFTMTRVNIIKGLGPVLQIAEGWSVELPKDVHDILNKRTNSTWPTTWFAPRL
                     TGKGPFTDVYSVMANWGANHGVLTIGHVGADFITLASMLRIPVCMHNVEETKVYRPSA
                     WAAHGMDIEGQDYRACQNYGPLYKR"
     gene            complement(13477..14793)
                     /gene="fucP"
                     /locus_tag="IRB70_003731"
     CDS             complement(13477..14793)
                     /gene="fucP"
                     /locus_tag="IRB70_003731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HBC0633593.1"
                     /translation="MGNTSIQTQSYRAVDKDAGQSRSYIIPFALLCSLFFLWAVANNL
                     NDILLPQFQQAFTLTNFQAGLIQSAFYFGYFIIPIPAGILMKKLSYKAGIITGLFLYA
                     FGAALFWPAAEIMNYTLFLVGLFIIAAGLGCLETAANPFVTVLGPESSGHFRLNLAQT
                     FNSFGAIIAVVFGQSLILSNVPHQSQDVLDKMSPEQLSAYKHSLVLSVQTPYMIIVAI
                     VLLVALLIMLTKFPALQSDNHSDAKQGSFSASLSRLARIRHWRWAVLAQFCYVGAQTA
                     CWSYLIRYAVEEIPGMTAGFAANYLTGTMVCFFIGRFTGTWLISRFAPHKVLAAYALI
                     AMALCLISAFAGGHVGLIALTLCSAFMSIQYPTIFSLGIKNLGQDTKYGSSFIVMTII
                     GGGIVTPVMGFVSDAAGNIPTAELIPALCFAVIFIFARFRSQTATN"
     gene            15340..15987
                     /gene="fucA"
                     /locus_tag="IRB70_003732"
     CDS             15340..15987
                     /gene="fucA"
                     /locus_tag="IRB70_003732"
                     /EC_number="4.1.2.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311687.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fuculose-phosphate aldolase"
                     /protein_id="HBC0633594.1"
                     /translation="MERNKLARQIIDTCLEMTCLGLNQGTAGNVSVRYQDGMLITPTG
                     IPYEKLTESHIVFIDGNGKHEEGKLPSSEWRFHMAAYQSRPDANAVVHNHAVHCTAVS
                     ILNRPIPAIHYMIAAAGGNSIPCAPYATFGTRELSEHVALALKNRKATLLQHHGLIAC
                     EANLEKALWLAHEVEVLAQLYLTTLAITDPVPVLSDEEIAVVLEKFKTYGLRIEE"
     gene            16015..17163
                     /gene="fucO"
                     /locus_tag="IRB70_003733"
     CDS             16015..17163
                     /gene="fucO"
                     /locus_tag="IRB70_003733"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417279.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBC0633595.1"
                     /translation="MANRMILNETAWFGRGAVGALTDEVKRRGYQKALIVTDKTLVQC
                     GVVAKVTDKMDAAGLAWAIYDGVVPNPTITVVKEGLDVFQNSGADYLIAIGGGSPQDT
                     CKAIGIISNNPEFADVRSLEGLSPTNKPSVPILAIPTTAGTAAEVTINYVITDEEKRR
                     KFVCVDPHDIPQVAFIDADMMDGMPPALKAATGVDALTHAIEGYITRGAWALTDALHI
                     KAIEIIAGALRGSVAGDKDAGEEMALGQYVAGMGFSNVGLGLVHGMAHPLGAFYNTPH
                     GVANAILLPHVMRYNADFTGEKYRDIARVMGVKVEGMSLEEARNAAVEAVFALNRDVG
                     IPPHLRDVGVRKEDIPALAQAALDDVCTGGNPREATLEDIVELYHTAW"
     gene            complement(17268..18023)
                     /gene="xni"
                     /locus_tag="IRB70_003734"
     CDS             complement(17268..18023)
                     /gene="xni"
                     /locus_tag="IRB70_003734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417278.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flap endonuclease Xni"
                     /protein_id="HBC0633596.1"
                     /translation="MAVHLLIVDALNLIRRIHAVQGSPCVETCQHALDQLIMHSQPTH
                     AVAVFDDENRSSGWRHQRLPDYKAGRPPMPEELHNEMPALRAAFEQRGVPCWSASGNE
                     ADDLAATLAVKVTQAGHQATIVSTDKGYCQLLSPTLRIRDYFQKRWLDAPFIDKEFGV
                     QPQQLPDYWGLAGISSSKVPGVAGIGPKSATQLLVEFKSLEGIYENLDAVAEKWRKKL
                     ETHKEMAFLCRDIARLQTDLHIDGNLQQLRLVR"
     gene            complement(18135..19502)
                     /gene="sdaB"
                     /locus_tag="IRB70_003735"
     CDS             complement(18135..19502)
                     /gene="sdaB"
                     /locus_tag="IRB70_003735"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase II"
                     /protein_id="HBC0633597.1"
                     /translation="MISVFDIFKIGIGPSSSHTVGPMKAGKQFTDDLIARNLLKDVTR
                     VVVDVYGSLSLTGKGHHTDIAIIMGLAGNLPDTVDIDSIPGFIQDVNTHGRLMLANGQ
                     HEVEFPVDQCMNFHADNLSLHENGMRITALAGDKVVYSQTYYSIGGGFIVDEEHFGQQ
                     DSAPVEVPYPYSSAADLQKHCQETGLSLSGLMMKNELALHSKEELEQHLANVWEVMRG
                     GIERGISTEGVLPGKLRVPRRAAALRRMLVSQDKTTTDPMAVVDWINMFALAVNEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFIREVNANSLARYLLVASAIGSLYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGASPAQVCIAAEIAMEHNLGLTCDPVAGQVQVPC
                     IERNAIAAVKAVNAARMALRRTSEPRVCLDKVIETMYETGKDMNAKYRETSRGGLAMK
                     IVACD"
     gene            complement(19560..20849)
                     /gene="sdaC"
                     /locus_tag="IRB70_003736"
     CDS             complement(19560..20849)
                     /gene="sdaC"
                     /locus_tag="IRB70_003736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease SdaC"
                     /protein_id="HBC0633598.1"
                     /translation="METTQTSTIASKDSRSAWRKTDTMWMLGLYGTAIGAGVLFLPIN
                     AGVGGMIPLIIMAILAFPMTFFAHRGLTRFVLSGKNPGEDITEVVEEHFGIGAGKLIT
                     LLYFFAIYPILLVYSVAITNTVESFMSHQLGMTPPPRAILSLILIVGMMTIVRFGEQM
                     IVKAMSILVFPFVGVLMLLALYLIPQWNGAALETLSLDTASATGNGLWMTLWLAIPVM
                     VFSFNHSPIISSFAVAKREEYGDMAEQKCSKILAFAHIMMVLTVMFFVFSCVLSLTPA
                     DLAAAKEQNISILSYLANHFNAPVIAWMAPIIAIIAITKSFLGHYLGAREGFNGMVIK
                     SLRGKGKSIEINKLNRITALFMLVTTWIVATLNPSILGMIETLGGPIIAMILFLMPMY
                     AIQKVPAMRKYSGHISNVFVVVMGLIAISAIFYSLFS"
BASE COUNT         5199 a         5110 c         5539 g         5222 t
ORIGIN      
        1 gtaattaaaa atattaatca gggagaataa aaatgaataa cacggatctt atctatctca
       61 ttaaacattt tatgcataac gaacttaaag cagtagaaga ggttattgat tccccacttt
      121 ctgaattcgc taatttaatt aaagtattac aatcttgtca gggaaaagtt gtttttattg
      181 gtgttggtaa gtccggtatt attgcccgaa aactcgcagc aacttttgcc agtaccggaa
      241 ctccctcgtt ttttgttcac ggtacggaag cggtacacgg cgaccttgga atggtggcga
      301 aagacgatgt tgttattctt atttcaaaca gtggtgagac ggcggaaatc ctggcgacac
      361 tgcctagtct gaaaaaaatg ggtaattatt tgatctcttt tacccgcagt catcactcat
      421 cgcttgcgat aagttgtgat ttatctgttg aaatccccgt caaaagtgag gcggataatt
      481 taggtttagc accgtcatgc tcgtcgactg ttgttctggt tgttggtgat gcggtggcgc
      541 ttgcactctc tgaattgaaa aaatttactc gtgctgattt cggcttatat catccaggag
      601 gtgcactcgg cattaaagca aattcataat ttcaaaatat aaatacagta accggtcacg
      661 ccatcttttg gggtggcgtt ctttgaagtg agtgtccgct atgaaaaatg ttctggtcac
      721 cgtccccagc ttttcagcac gctgtgtttc cgccagcaag ttgctaagag agaataattt
      781 taatcttatt attaagaata atgtggagca tctgcttaaa tcagaatcca ctgcattacg
      841 agaatctatt tgcgcggtca tcgccggaaa agattgttat caggcggaca cgctatcatt
      901 gctgtctggt gtgaaaataa tatcgagatt cgggacgggg atagacaata ttgatcttcg
      961 tgcggcacag caatcaggta ttattgtcaa taatgcggtt gggattaatt caaatgcggt
     1021 tgcggaattt atcattggac ttatcttcgc gagcatgaga aatatccccg gtagctatca
     1081 tgcgatgcaa aatggctact ggggtgagtc gcatggctgc gagttacaag gtaaacgtat
     1141 tggcctgctt ggctacggca atattggcaa aacactggcg aaaaggttat ctggttttga
     1201 tgttgagctt ttagcttttg acaaacaacc cgactatcag gttgctgaca aagctggagt
     1261 tcagtttgta tcaattgaag atatctttat gcagtcgcat gtcatcattg ttcttttgcc
     1321 tttttcttct gagctggaga actttattag tcataaatat ttgtcgatga tgcgcaatgg
     1381 tgctctgatc atcaatgccg caaggggaaa gttgctggat gagggcgctt tacttcaggt
     1441 gattgaagaa cgaaatgtgt ttgcggcgct ggatgtgttt agctctgaac cgttggcgca
     1501 atttagccca ctgctacatg ccaaaaatat cattacaacg ccgcatatcg cggcagccac
     1561 cgttgagtca taccagcaaa ccgggataca cgttgcccag tcgataattg attacttcgc
     1621 aggaagggag ataaaaaacg tgttgtgagt tcagcgaaca aagattttaa atacaaaaaa
     1681 accgcaatct gtgaaacaca ttgcggctta tcagcatcat aagtgttggt tgcgggggcc
     1741 ggatttgaac cgacgacctt cgggttatga gcccgacgag ctaccaggct gctccacccc
     1801 gcgtccgtgg atgcgcacta tactccgctc gcgttttcat gcaacctttt ttttacccag
     1861 atcacggatt tggtatgatt ttgagcaaaa acaaatcact aaagcctggt ttttgtgcaa
     1921 aatttgcgtc agggagaggc tgctcatttc attaaacgcg gcggtttgtt atcttcgttg
     1981 cgccttattt tttaacctga agaagagaac aatgaaagga cgttgggtaa agtaccttct
     2041 tatgggcacg gttgtggcaa tgcttgccgc ctgctcttcc aaaccaaccg atcgcggaca
     2101 gcaatataaa gacgggaaat ttacccagcc tttctctctg gtgaaccagc cagatgccgt
     2161 tggcgcgccg attaacgccg gtgattttgc cgagcaaatt aaccatatcc gtaattcgtc
     2221 accgcgtctg tatggcaacc agagtaatgt ttataacgcg gtgcaagagt ggctgcgcgc
     2281 aggcggtgat acccgcaata tgcgccagtt cggcattgat gcctggcaga tggaaggtgc
     2341 cgacaactat ggtaacgtgc agtttaccgg ttattacacg ccagtaattc aggcgcgcca
     2401 tacccgccag ggcgagtttc agtatccgat ttaccgtatg ccgccaaaac gtggtcgtct
     2461 gccgtctcgt gcggagatct acgcgggggc attgagcgat aaatacatcc tcgcttacag
     2521 caactctctg atggataact tcattatgga tgtgcagggt agtgggtata tcgactttgg
     2581 tgatggcagt ccgcttaact ttttcagcta tgcagggaaa aacggtcatg cctatcgcag
     2641 cattggtaag gtgctgatcg accgtggcga agtgaaaaaa gaagatatgt cgatgcaggc
     2701 gattcgtcac tggggtgaaa cacacagtga agccgaggtt cgcgagctgc tggaacagaa
     2761 cccgtctttc gtcttcttta aaccgcaatc ttttgctccg gtgaaagggg caagtgcggt
     2821 gccgctggtt ggtcgcgctt cagttgcgtc cgatcgttcc attatcccgc ctggtacaac
     2881 cttactggca gaagtgccgc tgctggataa taacggcaaa tttaacggtc agtacgaact
     2941 acggctgatg gtggcgttgg atgtcggtgg tgcaatcaaa ggccaacact tcgatattta
     3001 tcaaggtatc gggccggaag ccggacaccg cgcaggttgg tacaaccact atggacgtgt
     3061 ttgggtgctg aaaaccgccc cgggcgcagg taacgtcttt agcggctgat gtgttattct
     3121 gtataccgtt ttgacggata cgacagggtg agggataacc tcgccctttt taattctgag
     3181 gtgctatgtc tgtggtaatt agtgatgcat ggcgtcagcg ttttggtggc acagcgcgtc
     3241 tgtatggtga aaaagcattg caactgtttg ctgacgcgca tatttgtgtg gttggtatcg
     3301 gtggtgtcgg ttcctgggcg gcggaagcgc tggcgcgcac ggggattggc tcaatcacgc
     3361 ttatcgatat ggatgatgtg tgcgtcacca ataccaatcg gcaaattcat gccctgcgcg
     3421 ataacgttgg gctggcaaaa gcggaagtta tggcggagcg tattcgccag attaacccgg
     3481 agtgccgtgt aacggtggtg gatgatttcg tgacgccgga taacgtagcg cagtatatga
     3541 gcgtgggtta ttcgtacgtg attgatgcca ttgatagtgt acggcccaaa gcggcgctga
     3601 ttgcttattg tcggcgcaat aaaatcccac tggtcacaac cggtggcgcg ggtgggcaga
     3661 ttgacccgac gcagattcag gttaccgatc tggcgaaaac gattcaggac ccgctggcgg
     3721 cgaagttgcg tgagcgcctg aaaagcgatt ttggcatagt gaaaaacagt aaaggtaagc
     3781 tcggcgtgga ttgcgtgttc tctaccgaag cattggtgta cccgcagtca gatggcacgg
     3841 tctgtgcaat gaaagctacg gcggaagggc caaagcggat ggattgtgca tctggatttg
     3901 gtgccgcgac gatggtgacc gccacctttg gttttgttgc ggtttctcat gcgctgaaga
     3961 agatgatggc gaaagcggcg cgtcaggggt aaacaatcag gtcggatgcg acgcaaacgt
     4021 cctttccgac ccggttctgt gcttaaacct gcttcgccgc agcgataatc gcctcgctta
     4081 acgcattcaa cccctggctg cgtgaggcgc taagttgcgc acgcaatccc agctcatcaa
     4141 acaatgccag cggcgactgt gcctgcaatt cggcggcggt tttgccctca acggcagtca
     4201 acaacaccgc cagcaggccg cgcacaatgc gcccttcgct gtcgccaaag aagtgcattt
     4261 taccgttttc agccacggta tatcccagcc agacgcggtt ttcgcatccg gcaatctctt
     4321 tagcctgcgc ttttaactcg tctggcaaag ccggaagctg tttccccagc atgatcaact
     4381 ggcgatattt atcttcccat tgcgtcaacg gtgcgaaggt attgcgtaac gtttctgcgg
     4441 ttacggttgt gccgaacgga tgtccggcga attgcgggtt cgtcattaat ccaccaataa
     4501 ttccagcgcg cggtcaacgg cattcaccag cgcatccaca tcactctttg tattatatgg
     4561 cgcaaaagag gcgcgcagtg tgccggttac gcctaattct gccagtagcg gctgagcgca
     4621 atgctgcccg gcgcgcaggg caataccgta ctccgccagc agtgtcacca tatcgctgtg
     4681 atgaactcca gcaaaatcaa aggccagcag gctggaatcc tggcagcgaa atgagcggaa
     4741 gccaggacgt tttgccagcg catcttccgc cagcgttgct aagctacggc tccagctttc
     4801 ggcctggttg atatcgtaat ctgccagcca ttccagcgcc gcgcttaatc ctataacacc
     4861 agcgacattt ggcgttccgg cttccagttt ccacggcgca gattgagtcg tgaagccgtc
     4921 aaaactcact tcgtgaatca ttttgccgcc acccagccag ggtgacatcg cttccagcag
     4981 ttctgatttg ccatacagca cgccgatgcc tgtcgggcca tacagtttgt gaccagagaa
     5041 agcatagaaa tcgatatcca gttgctgaac atccgcaggg aaatgcaccg ccccctgagc
     5101 accatcaacc atcaccacca tcccggctga atgagcaaag gtaatcgctt gcgccagatc
     5161 cgggcaaccg ccagtgacgt tcgacatttg tcccagagca agaattcgac tacgaggtgt
     5221 gatcagttct ggcaacaaat cgacatccgg caatcgctgc gcattaagcg gcaatttcac
     5281 cacttgggct cccgtttgtt gggcgaccat cagccagggg acgaggttag cgtggtgttc
     5341 tgccacgctg acaataatct catcgcccgg ttgcagacgc ggacgcgcat agcattgtgc
     5401 caccatgttg atggattcag tggtgccgcg cgtccagacg atatttttgt catccggtgc
     5461 attcagtaat tgtgccactt tttcccgcgc agcttcgtaa cgcgcggtca ggcgttgggc
     5521 ttcggcaaac tggctgcgat ggacgtttcc ggcgctcagg ctataaaact gtcgggtggc
     5581 ttcaaccacg gcttcaggtt taagcgcggt cgcggcgctg tcgagataga cgcccgcatc
     5641 ctgtagcgcg ggaaactggg cgcgaaactg cgcgggatta aaaacgttca tggtactcct
     5701 cggcttgatg caccgatcgt gacgcaaaat tcactttgat acaaggagag tgctaaccat
     5761 cagaattatc tggatatcct ggcgaagccg cgtcagtaac atatgctgaa tagtgttagg
     5821 cgttaatttt agcctgttaa tcaatactat taagatttat taatcgcttt aaggagaaga
     5881 tgatgaaaaa gactgccgca attatttctg cctgtatgct gacttttgcc ctgagcgcct
     5941 gttccggttc gaactatgtg atgcacacca atgacggacg taccatcgtc tctgacggca
     6001 aaccacagac tgataacgat accggtatga tttcgtataa agacgctaat ggcaacaaac
     6061 agcagatcaa ccgtactgac gtgaaagaga tggtcgaact ggatcagtaa ttcgcgatcg
     6121 caaggtaaaa aaaagcaccg caattaggcg gtgctacatt aatcactatg gacagacagg
     6181 gtaaatgtac aggaagtgaa aaaaggtagc tttgctacca tggtctgaat cgcagaccaa
     6241 ttgcaaacac aacaacacaa catcacaacc gtaagccaaa agttcaccag aacacgcatt
     6301 ccgataaaac ttttcgttcc ggctcaggaa gtgccgccac tataggtatt tgctggtaga
     6361 agctcaacgg acaatttata atggctcaga ttaaaaaaac taataggtta cacagtgtga
     6421 tctaattgtt aaattcattt aacatcaaag tttaaaagcc atgtctaaac gattaccacc
     6481 gctaaatgcc ttacgagttt ttgatgccgc agcacgccat ttaagtttca ctcgcgcagc
     6541 agaagagctt tttgtgaccc aggccgcagt aagtcatcaa atcaagtctc ttgaggattt
     6601 tttggggcta aaactgttcc gccgccgtaa tcgttcactc ctgctgaccg aggaagggca
     6661 aagctatttc ctcgatatca aagagatatt ttcgcaatta accgaagcga cgcgtaaact
     6721 ccaggcccgt agcgccaagg gggcgttgac ggtcagttta ctccccagtt tcgccattca
     6781 ttggttggtt ccgcgacttt ccagctttaa ttcagcttat ccgggaattg acgttcgaat
     6841 ccaggcggtt gatcgtcagg aagataagct ggcggatgat gttgatgtgg cgatatttta
     6901 tggtcgtggc aactggccgg ggctacgggt ggaaaaactg tacgccgaat atttattgcc
     6961 ggtgtgttcg ccgctactgc tgactggcga aaaacccttg aagaccccgg aagatctggc
     7021 taaacatacg ttattacatg atgcgtcacg ccgtgactgg cagacatata cccgacagtt
     7081 ggggttaaat catatcaacg ttcagcaagg gccaattttt agccatagcg ccatggtgct
     7141 gcaagcggct atccacgggc agggagtggc gctggcaaat aacgtgatgg cgcaatctga
     7201 aattgaagcc ggacgtcttg tttgcccgtt taatgatgtt ctggtcagta aaaacgcttt
     7261 ttatctggtt tgtcatgaca gccaggcaga actgggtaaa atagccgcct ttcgtcaatg
     7321 gatcctggcg aaagccgctg ctgaacaaga aaaattccgc tttcgttatg aacaataatt
     7381 tacgtagggt acgaccatga ccagccgttt tatgctgatt ttcgccgcca ttagcggctt
     7441 catttttgtg gctctgggcg cttttggcgc gcatgtgtta agtaaaacca tgggggccgt
     7501 tgagatgggc tggatccaga ccggtctcga ataccaggcg ttccacacgc tggcgatctt
     7561 aggtctggcg gtggcaatgc agcgtcgcat cagtatctgg ttttactgga gtagcgtttt
     7621 cctcgcgtta ggcacggtgc tgttcagcgg cagcctttat tgcctggcgc tgtcccatct
     7681 gcgtttgtgg gcgtttgtca caccggttgg cggcgtgagc ttccttgcgg gctgggcgtt
     7741 aatgttagtt ggtgctatcc gtttaaagcg caagggcgta agtcatgaat aaggttgtat
     7801 tgctgtgccg tccgggcttt gaaaaagagt gcgccgcaga aattaccgat aaagccggtc
     7861 agcgggaaat tttcggtttt gcccgcgtga aagagaatgc gggttatgtc atttatgaat
     7921 gttatcaacc tgatgatggc gataagttaa tccgtgagct gccgttcagt tcattaattt
     7981 ttgcccgcca gtggtttgtg gtgggggaac tcctgcagca tttgccgcct gaagatcgta
     8041 ttacccccat tgtcggtatg ttacagggcg tagtagagaa gggcggtgaa ctgcgtgttg
     8101 aagttgccga taccaacgaa agcaaagagt tgctgaaatt ctgccgtaaa ttcaccgtgc
     8161 cgctacgcgc tgccttgcgt gatgcggggg tgctggcgaa ctatgaaacg ccgaagcgtc
     8221 cggttgtgca tgtattcttt attgcaccag gctgttgcta taccggttac tcatacagca
     8281 acaataattc gccgttctat atgggcattc cgcgcctgaa atttccggca gatgcgccga
     8341 gtcgttccac gctcaaactg gaagaggcat ttcatgtgtt tattcccgcg gatgagtggg
     8401 atgaacgcct ggcgaacggg atgtgggcgg tggatttggg cgcttgccca ggcggctgga
     8461 cctaccaact ggtgaagcgc aacatgtggg tttattccgt cgacaacggc ccgatggcgc
     8521 aaagtctgat ggataccgga caggtgacgt ggctgcggga agacggtttc aaattccgtc
     8581 cgacacgcag caatatctcc tggatggtat gcgatatggt tgaaaaaccg gcgaaagttg
     8641 cggcattgat ggcgcagtgg ctggttaatg gctggtgccg tgaaagcatt ttcaacctca
     8701 aactgccgat gaaaaaacgc tacgaagaag tgtcacacaa tctggcgtat attcaggcac
     8761 agcttgatga acatggcata aatgctcaga tccaggcgcg gcagttgtat cacgatcgcg
     8821 aagaagtgac ggtgcacgtc cgccgtatct gggctgcggt gggtggtcgt cgcgacgagc
     8881 gataacaggc aaggccgggg cgtcgtctcc ggcctgctac cctttccgtc aggctgttac
     8941 caaagaagtt gcaacctggc gctcatcaga aataatgtgc gtgacctcat ccagatgccc
     9001 gatgcgggct tcccctgaac gattaaattt acttttatca atcaataaca acgattgtgc
     9061 ggcgcgtttt aatagcattg atttgtaatc agcgttgatg gcattggagt cccacagtgc
     9121 gccgctgcta tcgatccctt cacaagaaaa aataaacaga tcgatttcca gcgatttaag
     9181 ctgggaaatc agcgagggat tgacgtaaca accatatttg cgctcaagtg tgccgccgga
     9241 actgatcagt tgaatgcgtt cacgtttacc gagttcatgg caaatcggat ggctattggt
     9301 gaagacctgg atgttgatgt caggcaactg gcgtgccaga taccagcagg ttgaactggc
     9361 gtctaatgct attaccatcc cttcttcaat ccacgcgagc gcctcgcgcg cgatatctgc
     9421 tttatgcgca taatggcttt tcaaccggat gtgaaaggga tcgccactgt cttgattttg
     9481 acggtggata tatttagcgc gtccatgatt gcgcagaatt ttaccctgcg tctgtaattc
     9541 attgagatcg cgacgaatgg tttctttact gacctttagc tgttcagaga gagcttccgt
     9601 ggtcaggctg gtatggttca gcagcaggtc gactatcgct tgctggcgtg ccgctttcat
     9661 atttttcacc ccatcattcg ataaccgccc gcgtcatgcg ggcgtaccgg tatgagatta
     9721 cggtgttacc ccttttttta aaagaatatt cccgtacttc gctcgttcgc ctgtgataac
     9781 gatcgcaaag gctttttgcg cccgttcata aaacgcaaaa cgattgatgc ggatgatgtc
     9841 aggacagggg gcttgtagtg aaagcgcatt acgataacgt cgttctactt caggatcgag
     9901 agtgtcacct tctaccgccg ccatcatcac cagcggcggt gcataactgt ccagttcaaa
     9961 taacgggata atcgcctgga gcaagtcact caccaacagg ccatcagcgc ggatcacctg
    10021 cggtcccatc gaatgggcgg gaaagtgagc atcggaaaaa ataatttcat ctccatgccc
    10081 catctctgcc agcactttca atagttcggg agaaattaac ggcgaaattg ttttcagcat
    10141 ttcacacttc ctctataaat tcaggttcag tttgcgggta gaaataacgg tactgataat
    10201 gaatctgcgc gcgggcttct tccgggctgt taaattcccc tacgccatac caaccgaaca
    10261 gcgcagctcc tgcgacggtc gtttcggcgt cgtcgagaac ttttaccgga atatcaagca
    10321 tattggcttt aatctgattc cacaatgtgt tgcgacttcc tccgccgact aacaataatt
    10381 cagaggcttt aaagtgcccg attttttcca gcatctgtag attgcgctgt aattgcgcag
    10441 ttaacccttc cagcgccgcg cgatagaaat gcccccgcgt ggtattaagc gtcactcctt
    10501 gccagccagc gttctgacac gacaataaat cacactgcat tttcacacca tccgcgccag
    10561 gtgcgatcag acgagcttct tcaatcaaca tttgccaggg agtttcagcc gtccagaaca
    10621 gttttctcac ccattccagc acgccggatg ccagccattg catacctggg ttatacaacc
    10681 ctgcctggct atccagttcg caggtggaac cggcgtactg acttaacagc gaagtatcaa
    10741 cctgggcgct gcggaccatt aaaatttccc atgtaccgga agagagcacg ggttcatttt
    10801 gttcggcacc agcgccaaaa agagcgaact gggtatcgtg acctgcggaa atcaccggta
    10861 tgccaacgga taagccgagc attgctgcgg cgctgttctg tagcgtacca atctgttcac
    10921 ccgcttccac cagacgaggg aagagtcggc gtggaatacc ggtggcttgt aaaatttgcg
    10981 gactgaaatc gcgttgctgg atatccagca tctggctggt tccggccatc gtaatatcag
    11041 tagtgaattc gccggttaaa cggtggttaa tcagcgacga aataaagagc caggcgtgcg
    11101 cgcgttccag cagttgtgga tgattttctt tcaaccacac caacttatat aacgtattga
    11161 aactaaaggc tccgacgcca gaaatagcct gcaactgctg tgcggagatc aaccgttcaa
    11221 tattgtccat taccgctgct gttcgcggac atttccagct aatgatcgga tagagcagat
    11281 tgccttgctt atctaccaga gcgccatcca caccaaaggt ggtgacggcg ataccgcgga
    11341 tgtggcaatc agtcagttca ctattgattt gccgacagca atcagcaaag cgttgcaaaa
    11401 tggcgtctaa agaccactgg tgccaggtgt tgttttccat cgcgatatcg ctggcattag
    11461 gcgttgaggc gcgggcaaca atttttccct gccgattaac cgcgatggcc ctgacattgg
    11521 tcgcgccaca gtcgagtacc aggataactt cttgtttcat aatcgctcct gcaatatagc
    11581 cggataacat tgcttatccg gctaaccact cttgcttgtt caggcccggt agccggagcg
    11641 accgggcatc acatcaggga gtcatgtatt aacgcttgta caacgggccg tagttctggc
    11701 aagcgcggta atcctggcct tcaatatcca tgccgtgcgc ggcccaggca gaaggacgat
    11761 acactttggt ctcttcaacg ttgtgcatac ataccgggat acgcagcatg gaggcaagag
    11821 tgataaagtc tgcgccaacg tggccgatgg tcagaacccc gtggttagcg ccccagttcg
    11881 ccattaccga gtacacatcc gtaaacggcc ctttaccggt gaggcgcggt gcaaaccagg
    11941 tggttggcca ggttgagttg gtgcgtttgt tgaggatgtc atgcacatcc ttcggcaatt
    12001 ccacgctcca gccttccgcg atttgcagta ccggtcccag gcctttgatg atgttgacac
    12061 gagtcatggt gaacgggacg ccgccttcgg taaggaagcg ggaagagtaa ccgccgccac
    12121 ggaagtattc gtggatcgcc gggcaccatt cggtagcggc gaggcaagcg tcagcctctt
    12181 gctgagagat ttcccagtgt ggcttcatcg tcgggttacc ttcgctgtcg cgttgtttac
    12241 aggaaccgtc cagcgcagca gaaccggagt tgatcaaatg gatgatgccg tgttctgcca
    12301 gtccatcgag tttatgcccc gttacacgct caattgcttc tggtgaccag taggtacgca
    12361 catcggcaaa tacctgagcg gtgccggtga gttggtgacc cattagcatt gccacgccgt
    12421 taagactgtc gttttcggtc gccacgacaa agggttcgcg cacgccattc cagtcaaatg
    12481 aactgttgag gagcgcttcg gcggtgtcac cattgggata ttgatcggtc cagtggcgtt
    12541 gtccctggaa gcccgcagcg atggcgttgt agccaagtga ttcttccacg cgaccaatat
    12601 cggccagttt gctgttgcct tgcatcatgt cgcggataca cattgccatc agtaaacttt
    12661 cgcgcagaac tgcgcggctt tgctcggcat tgcgttgata ctgtttgtta ttttcatctt
    12721 cgccatagcg gaagttttta tcagcccagg ccagcgccat ttccagttcg gcttcgtcgt
    12781 aaatcttctg atcgatacgg cgacgcagtt cggtcatatc caccgcctgg actttcattc
    12841 ccagccagga ttcaaagaag ttgtgatcaa caatagaacc ggcgataccc atcgaaacgc
    12901 cgcccagcga cagatagctt ttacctttca tgctggcgac ggccaaaccg gcgcgggcaa
    12961 agcgcagcag tttttcttca acatcagcag gaatcgatgt gtcatcggca tcctgaacgt
    13021 catgaccgta aatggagaat gccgggatgc ctttctggct gtgagctgcc agagccgctg
    13081 ccaggtaaac agcgccggga cgttcggtgc cgttaaagcc ccaaatggct ttcgggcggg
    13141 ttggatccat gtcgatggtt tcactgccat agcaccagca aggggttacc gtaatggtga
    13201 ggcctacatt ctgactgctg aatttttctt cgcaagcagc ggcttcagcc atacccgcga
    13261 tacaggtatc ggaaatgaca cactcgacgg cagctccaca ggcatggcgc agtttctcgg
    13321 tcagcagtgc ggccgtggct ttcgccatat tcattgtttg ttcttcaagc gactcacgaa
    13381 cacccatgcg acgaccgtca ataaccgggc ggataccaat tttcggtaag ctgatttttt
    13441 tcattacaga ttcctcactt tattcggaaa atatgttcag ttagttgccg tttgagaacg
    13501 gaaacgggca aagataaaga tgactgcgaa gcagagtgcg gggatcagtt cagctgtggg
    13561 gatgttgccc gcagcgtcac tgacaaaacc catgaccgga gtgacaatac cgccgccaat
    13621 aatggtcata acgatgaagg acgaaccgta tttggtgtcc tggccgagat tcttaatgcc
    13681 cagcgagaag attgttgggt actgaatcga cataaaggcg ctgcataaag tcagggctat
    13741 taagcccaca tgaccgccag cgaaggctga gatcaggcac agtgccatag cgattaatgc
    13801 gtaggctgcc aggactttgt gtggtgcgaa gcgactgatg agccaggtac cggtgaaacg
    13861 accaataaag aagcacacca tggttccggt taaatagtta gcggcaaagc ctgcggtcat
    13921 acctggaatt tcttctacag cgtagcgaat caaatagctc cagcaggccg tttgcgcgcc
    13981 gacgtagcag aattgcgcta atactgccca gcgccagtgg cgaatacgcg ccaggcgaga
    14041 aagcgatgcg gagaacgatc cttgtttggc gtcactgtga ttatcactct gcaatgccgg
    14101 gaatttcgtc agcatgatca gcagggcgac cagtaacacg atagccacga tgatcatata
    14161 aggtgtctgt accgataata ccaggctgtg tttatacgca ctcaattgct ctggagacat
    14221 tttatcgaga acgtcttgcg attgatgtgg cacgttagac aaaataagac tttgcccaaa
    14281 gacaaccgcg ataattgcgc caaatgagtt aaatgtttgc gcaagattta agcggaagtg
    14341 accactgctt tccggcccta ataccgtaac aaaagggttt gcggcagttt ccagacaacc
    14401 taatccggct gcaataataa ataggccaac taaaaacaat gtgtagttca ttatttctgc
    14461 ggcgggccag aataatgcag cgccgaaggc atataaaaac aatccggtaa taatccctgc
    14521 tttataactg agttttttca tcaatatccc ggcagggatt gggataatga aataaccaaa
    14581 gtaaaaggcc gattggatca ggccagcctg gaaatttgtc agcgtaaaag cctgctggaa
    14641 ttgaggcaat aaaatgtcgt taaggttatt ggctaccgcc caaagaaaaa acagtgagca
    14701 cagcagtgca aatggaataa tgtaacttct gctttgccct gcatctttat ctaccgcacg
    14761 gtaactctgc gtttgtattg atgtgtttcc catagcatcc tcttaggttc agaagcttaa
    14821 gcacgtaatc ggttatgttt tcaaaagtgc aaaaccagcg agttcgggct tcatatcagt
    14881 gaatatttgc ctgtctgaaa tgaactcatg gattcatttt caaataaaaa acgctctgta
    14941 atatgacggc ggtcacactt attagccgga aggtgacttt atgtgactac catcacttta
    15001 ataatcgaaa tttcatgccc gtttcagaaa ataaatcata aaaaacacaa accagatgac
    15061 cgtattaatt gtttgtgccg aaaacgggca ttcctggcag ggaggagtag aaaaatgacc
    15121 gttttgataa atatttttaa gagcggtcat ttttaatggg gttataaaaa gagaaattgc
    15181 agttatttac tgtgattagt tgaaccaggt cacaaaatat aagcttgtga atttctttct
    15241 ggttaatcag gaagaatatg gtgagtaatt aaacggctaa ttcaatagtg tgaaaggaac
    15301 aacattattg ccctgttttg aatcagagag aggtagctaa tggaacgaaa taaacttgct
    15361 cgtcagatta ttgacacttg cctggaaatg acttgcctgg ggctgaacca ggggacagcg
    15421 ggtaacgtca gtgtacgtta tcaggatggg atgctgatta cgcctacagg tattccatat
    15481 gaaaaactga cggagtcgca tattgtcttt attgatggca acggcaaaca tgaggaagga
    15541 aaactcccct caagcgagtg gcgtttccat atggcggcct atcaaagcag accggatgcc
    15601 aacgcggttg ttcacaatca tgccgttcat tgtacggcag tttccattct taaccgaccg
    15661 atccccgcga ttcactacat gattgcggcg gctggcggta attctattcc ttgcgcgcct
    15721 tatgcgacct ttggaacacg cgaactttct gaacatgttg cgctggctct caaaaatcgt
    15781 aaggcaactt tgttacaaca tcatgggctt atcgcttgtg aggcgaatct ggagaaagcg
    15841 ttatggctgg cgcatgaagt tgaagtgctg gcacaacttt acctgacgac cctggcgatt
    15901 acggacccgg tgccagtgct gagcgatgaa gagattgccg tagtgctgga gaaattcaaa
    15961 acctacgggt tacggattga agagtaattt cgtaaagcaa caaggagaag gatgatggct
    16021 aacagaatga ttctgaacga aacggcatgg tttggtcggg gggctgttgg ggctttaacc
    16081 gatgaggtga aacgccgtgg ttatcagaag gcgctgatcg tcaccgataa aacgctggtg
    16141 caatgcggcg tggtggcgaa agtgaccgat aagatggatg cggcaggact ggcatgggcg
    16201 atttacgacg gcgtcgtgcc caacccaaca attactgtcg tcaaagaagg gctcgatgta
    16261 ttccagaata gcggcgcgga ttacctgatc gctattggtg gtggttctcc acaggatact
    16321 tgtaaagcga ttggcattat cagcaacaac ccggagtttg ccgatgtgcg tagcctggaa
    16381 gggctttccc cgaccaataa acctagtgta ccgattctgg caatccccac cacagcaggc
    16441 actgcggcag aagtgaccat taactacgtg atcactgacg aagaaaaacg gcgcaagttt
    16501 gtttgcgttg atccgcatga tatcccgcag gtggcgttta ttgacgctga catgatggat
    16561 ggtatgcctc cagcgctgaa agctgcgacg ggtgtcgatg cgctcactca tgctattgag
    16621 gggtatatta cccgtggcgc gtgggcgcta accgatgcac tgcacattaa agcgattgaa
    16681 atcattgctg gggcgctgcg aggatcggtt gctggtgata aggatgccgg agaagaaatg
    16741 gcgctcgggc agtatgttgc gggtatgggc ttctcgaatg ttgggttagg gttggtgcat
    16801 ggtatggcgc atccactggg cgcgttttac aacacgccac acggtgttgc gaacgccatc
    16861 ctgttaccgc atgtcatgcg ctataacgct gactttaccg gtgagaagta ccgcgatatc
    16921 gcgcgcgtta tgggcgtgaa agtggaaggt atgagcctgg aagaggcgcg taatgccgct
    16981 gttgaagcgg tgtttgctct caaccgtgat gtcggtattc cgccacattt acgtgatgtt
    17041 ggtgtacgca aggaagacat tccggcactg gcgcaggcgg cactggatga tgtttgtacc
    17101 ggtggcaacc cgcgtgaagc aacgcttgag gatattgtag agctttacca taccgcctgg
    17161 taaatgcgct gatgtgataa tgccggatgc gacgctagcc gtgtcttatc cggcatataa
    17221 gtgcattaaa ttcaatgtgt tgataatcgt ttgcatccgg cacgccgtta ccgtaccaac
    17281 cgcaattgct gtaaattgcc gtcgatatgc aaatcggttt gtaagcgggc aatatcgcgg
    17341 cacagaaacg ccatctcttt atgggtttct aattttttgc gccacttttc ggcaaccgca
    17401 tccagattct catatatccc ttccagactc ttaaactcga ccagcagctg cgtggcgctt
    17461 tttggtccga tccccgcaac acccggtacc tttgaactgc tgatccccgc aagtccccag
    17521 taatcgggta actgctgcgg ttgaacgcca aattctttat caataaatgg tgcatccagc
    17581 caacgtttct ggaagtaatc acgaatacgt aatgtcggtg aaagtaactg acagtagcct
    17641 ttatctgtcg aaacaatcgt tgcctgatgc ccggcctgtg tcactttgac cgccagcgtg
    17701 gcggctaagt catcggcttc gttgccgctg gcggaccagc acgggacgcc gcgttgctca
    17761 aaggcggcgc gtagtgcagg catctcgttg tgcaactctt ccggcattgg cggtcgaccc
    17821 gctttgtaat ctggtaaacg ctgatgacgc cagccgctac tgcggttttc atcatcaaaa
    17881 acggcgaccg cgtgggttgg ctggctgtgc ataatgagct gatcgagcgc gtgctggcag
    17941 gtttcgacac agggcgaacc ctgaacggca tgaatgcgac gaataagatt cagtgcatcg
    18001 acaataagca aatgaacagc cacgataacc cccttaaaga tcaggcgata agggtaacat
    18061 tcgatgccgg aacaggctat ggctggttga gaaaacggga agaggcctcg caaaaagagg
    18121 cctctggaga gcgattaatc gcaggcaacg atcttcattg ccaggccgcc gcgagaggtt
    18181 tcgcggtact tggcgttcat atctttacct gtttcgtaca tggtctcgat aactttatcg
    18241 aggcagacgc gcggctcgct ggtacggcgc agcgccatac gcgcggcgtt caccgctttt
    18301 actgccgcaa tggcgttacg ctcgatgcac ggtacctgga cctgtccggc aaccgggtca
    18361 cacgtcagac cgaggttgtg ctccatggcg atttccgccg cgatgcatac ctgcgccggg
    18421 cttgcgccta acagttctgc cagaccagct gccgccattg agcacgccac gccgacttca
    18481 ccctggcagc cgacttcggc accagaaatc gacgcgttca tcttataaag agaaccaatg
    18541 gcgctggcta ccagcaggta acgagccagt gagttagcgt tcacttcgcg gataaacttg
    18601 tcgtagtacg ccagcacggc cggaataatc ccgcacgcac cgttagtcgg cgcagtcacc
    18661 acacgaccgc cagcagcatt ctcttcgttc actgccagtg caaacatgtt gatccagtca
    18721 acaaccgcca tcgggtcagt ggtggtttta tcctggctga ccagcatccg gcgtagtgcc
    18781 gcagcacggc gtggaacgcg cagtttgcca ggcaacacgc cttcggtgga aataccgcgc
    18841 tcaataccgc cacgcatgac ttcccagacg ttcgccaggt gctgttccag ctcttctttg
    18901 ctgtgcagtg ccagctcgtt tttcatcatc aggccagaga gtgacagccc ggtttcctga
    18961 caatgttttt gcagatcggc tgctgaactg tacggataag gaacttcaac cggtgcgcta
    19021 tcctgctgac caaaatgctc ttcatcaacg ataaagccac cgccaataga gtagtaagtc
    19081 tggctgtaaa cgactttatc gcccgccagt gcggtaatgc gcataccgtt ttcatgcaga
    19141 gaaaggttgt cggcatggaa gttcatgcac tgatcaaccg ggaactccac ttcatgctga
    19201 ccgtttgcca gcatcaggcg accatgagta ttcacatcct gaataaaacc agggatggaa
    19261 tcgatatcca cggtatccgg caggttaccc gccagaccca taattatggc gatatctgtg
    19321 tggtggcctt taccggtcag agagagcgag ccgtacacgt caaccaccac gcgggtcacg
    19381 tctttaagca ggttacgggc aatcagatcg tcggtaaatt gtttacccgc tttcattggt
    19441 ccaacggtat gagaactgga agggccaatg ccgattttga aaatatcgaa tacgctaatc
    19501 ataggaaata catcgcgtta aaacggagga agcgccgccc gaaagcggcg cgaaaggact
    19561 tagctgaaca gagagtagaa gattgcggag attgcaatca gacccatcac gacaacgaat
    19621 acgttgctga tgtgaccgct gtacttacgc attgccggta ctttctgaat tgcgtacatc
    19681 ggcatcagga acaggatcat cgcgatgatt gggccgccca gggtttcaat catacccagg
    19741 atgctcgggt tcagggtggc aacaatccag gtcgttacca gcatgaacag cgcagtgata
    19801 cggttcagct tgttgatttc gatagactta cctttaccac gcagagattt aatcaccata
    19861 ccgttgaagc cttcacgtgc gcccaggtag tggccgagga aggatttggt gatagcgata
    19921 atcgcgataa tcggagccat ccacgcgata accggtgcgt taaagtggtt agccaggtaa
    19981 gacagaatcg agatgttctg ctctttagcc gcagccaggt ctgccggagt caggctcagt
    20041 acgcagctga atacgaagaa cattacggtc agcaccatca tgatgtgtgc gaatgccagg
    20101 atcttcgagc atttctgttc tgccatatcg ccgtactctt cacgcttcgc aacggcgaaa
    20161 gaagagatga tcggagagtg gttgaacgag aacaccatta ccggaattgc cagccacagg
    20221 gtcatccaca gaccgtttcc ggttgcagat gcagtgtcca gagacagcgt ttccagtgct
    20281 gcgccgttcc actgcgggat caggtacaga gccagcagca tcagtacgcc aacaaacggg
    20341 aataccagaa tactcatcgc tttaacgatc atctgctcac cgaagcgaac gatggtcatc
    20401 atacccacga tcaggatcag cgacagaatc gcacgcggcg gtggtgtcat acccagctgg
    20461 tgagacatga agctttcaac tgtattggtg attgccacgc tataaaccag caggatcggg
    20521 tagatagcga agaagtagag cagggtaatc agtttacctg cgccaatacc aaagtgttct
    20581 tctacaacct cggtgatgtc ttcgcctggg tttttaccag acagtacgaa gcgagtcagg
    20641 ccgcggtgag caaaaaatgt catcgggaac gcaaggatag ccatgatgat cagcgggatc
    20701 ataccgccaa caccggcgtt gattggcagg aacagcacgc ccgcgccgat tgccgtgccg
    20761 taaaggccca gcatccacat ggtgtctgtc ttgcgccagg cactacgaga gtctttcgac
    20821 gcaatcgtgc tggtttgagt cgtttccatc tatttctcct ggaggaatgc aaataattca
    20881 gcttttagcc agttcagccc gggaaggtgc ctgaccgtaa aaatgaaatc tgtctatcgg
    20941 cgatggctta atcatttacc gccgtaataa tttgagggcg gaaagataca cacaagttat
    21001 gtatctatca gtgatcttga tcccaaatac aataatctac ttggaagata gattatccca
    21061 acgctttact
//
LOCUS       DADXDL010000089        20992 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.089, whole genome shotgun sequence.
ACCESSION   DADXDL010000089 DADXDL010000000
VERSION     DADXDL010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20992)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20992)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20992
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.089"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1435
                     /locus_tag="IRB70_003737"
     CDS             <1..1435
                     /locus_tag="IRB70_003737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HBC0633599.1"
                     /translation="NQSATDTLSSPVPETDAVETAIPGNEKTECKVEVEPSVEREGPF
                     YFLFTDKDGEKYGRANKLSGLEKALALGATEITKEEYFARKNGTYSGSQQNTGASDTT
                     AQPEPVKVTADEVNKIMQAANISQPDADKLLAASRGEFVAGISDPNDPKWVKGIETRD
                     SVNQNQQESEQNDQKAEQNSPNTQQNEPETKQPEPVAQQEPEKVCTACGQSGGGNCPD
                     CGAVMGDATYQETFDEENQVEVQENDPKEMEGAEHPHKENAGSAQDHASDSETGETAD
                     PLITMNGHHVITSTSRTCDHLMIDLETMGKNPDAPIISIGAIFFDPQTGDMGPEFSKT
                     IDLETAGGVIDRDVIKRWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVQV
                     WGNGANFDNTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERH
                     NALDDARYQAKYVSVIWQKLIPNQADF"
     gene            1500..1748
                     /locus_tag="IRB70_003738"
     CDS             1500..1748
                     /locus_tag="IRB70_003738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase"
                     /protein_id="HBC0633600.1"
                     /translation="MARLILLTEWAKEEFSEPVPTPSTLSKYAKAGMIFPLPKKVGRR
                     WRVDPQARFVGMVNKPEVIATDHPALKRILEDGAPAKI"
     gene            1726..2856
                     /locus_tag="IRB70_003739"
     CDS             1726..2856
                     /locus_tag="IRB70_003739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase Arm DNA-binding
                     domain-containing protein"
                     /protein_id="HBC0633601.1"
                     /translation="MARPRKYKTNVPGLSPYFDKRNNKVYWRYRHPITGKNHGLGSID
                     QKLAETIAAEANSRIARQQMEQMLSLQEKIISDTGGSSTVTIFLNNYRKIQQERYENG
                     EIKLNTLKQKAAPLRVFDERFGTRPLDAITVKDVVSVLEEYKARGHNRMGQIFRKVLI
                     DVFREAQQTGDVPPGFNPAESAKKPQVRISRQRLTFDEWMMIYNAAEKDGYFLQRGML
                     LALMTGQRLSDICKMQFSDIRDGYLHVEQQKTGTRIAIPLALRCDKLNLTLDDVVSSC
                     RDCVLSPWLLHHHHAKGTAKRGGMVKPATLTVAFKKARDSVDYNWRANGTPPSFHEQR
                     SLSERLFREQGVDTKILLGHSNQKMTDIYNDARGKEWKKLVI"
     gene            complement(2902..3540)
                     /gene="ompW"
                     /locus_tag="IRB70_003740"
     CDS             complement(2902..3540)
                     /gene="ompW"
                     /locus_tag="IRB70_003740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
                     /protein_id="HBC0633602.1"
                     /translation="MKKLTVAALAVTTLLSGSAFAHEAGEFFMRAGSATVRPTEGAGG
                     TLGSLGGFSVTNNTQLGLTFTYMATDNIGVELLAATPFRHKIGTRATGDIATVHHLPP
                     TLMAQWYFGDASSKFRPYVGAGINYTTFFDNGFNDHGKEAGLSDLSLKDSWGAAGQVG
                     VDYLINRDWLVNMSVWYMDIDTTAKYKSGVTTVKDSVRLDPWVFMFSAGYRF"
     gene            3780..3869
                     /locus_tag="IRB70_003741"
                     /pseudo
     CDS             3780..3869
                     /locus_tag="IRB70_003741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_460692.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YkgJ family cysteine cluster protein"
     gene            3897..4640
                     /locus_tag="IRB70_003742"
     CDS             3897..4640
                     /locus_tag="IRB70_003742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0259 family protein"
                     /protein_id="HBC0633603.1"
                     /translation="MSITAQSVYRDTGNFFRNQFMTILLVSLLCAFITVVLGHVFSPS
                     DAQLAQLNDGVPVSGSSGLFDLVQNMSPEQQQILLQASAASTFSGLIGNAILAGGVIL
                     IIQLVSAGQRVSALRAIGASAPILPKLFILIFLTTLLVQIGIMLVVVPGIIMAILLAL
                     APVMLVQDKMGVFASMRSSMRLTWANMRLVAPAVLSWLLAKTLLLLFASSFAALTPEI
                     GAVLANTLSNLISAVLLIYLFRLYMLIRQ"
     gene            4670..5209
                     /locus_tag="IRB70_003743"
     CDS             4670..5209
                     /locus_tag="IRB70_003743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation protein A"
                     /protein_id="HBC0633604.1"
                     /translation="MKQFLDFLPLVVFFAFYKIYDIYAATAALIVATAIVLIYSWVRF
                     RKVEKMALITFVLVVVFGGLTLFFHNDEFIKWKVTVIYALFAGALLVSQWVMKKPLIQ
                     RMLGKELTLPQPVWSKLNLAWAVFFILCGLANIYIAFWLPQNIWVNFKVFGLTALTLI
                     FTLLSGIYIYRHMPQEDKS"
     gene            5314..5712
                     /gene="yciA"
                     /locus_tag="IRB70_003744"
     CDS             5314..5712
                     /gene="yciA"
                     /locus_tag="IRB70_003744"
                     /EC_number="3.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioester hydrolase YciA"
                     /protein_id="HBC0633605.1"
                     /translation="MSTTHNVPQGDLVLRTLAMPADTNANGDIFGGWLMSQMDIGGAI
                     LAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCVQKGTTSVSINIEVWVKKVASE
                     PIGQRYKATEALFKYVAVDPEGKPRALPVE"
     gene            complement(5752..6468)
                     /gene="tonB"
                     /locus_tag="IRB70_003745"
     CDS             complement(5752..6468)
                     /gene="tonB"
                     /locus_tag="IRB70_003745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB system transport protein TonB"
                     /protein_id="HBC0633606.1"
                     /translation="MTLDLPRRFPWPTLLSVCIHGAVVAGLLYTSVHQVIELPAPAQP
                     ISVTMVAPADLEPPQAVQPPPEPVVEPEPEPEPIPEPPKEAPVVIEKPKPKPKPKPKP
                     VKKVEQPKRDVKPVESRPASPFENTAPARPTSSTATAATSKPVTSVASGPRALSRNQP
                     QYPARAQALRIEGQVKVKFDVTPDGRVDNVQILSAKPANMFEREVKNAMRRWRYEPGK
                     PGSGIVVNILFKINGTTEIQ"
     gene            6692..6988
                     /locus_tag="IRB70_003746"
     CDS             6692..6988
                     /locus_tag="IRB70_003746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415767.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciI family protein"
                     /protein_id="HBC0633607.1"
                     /translation="MLYVIYAQDKADSLEKRLSVRPAHLARLQLLHDEGRLLTAGPMP
                     AVDSNDPGAAGFTGSTVIAEFESLEAAQAWADADPYVAAGVYEHVSVKPFKKVF"
     gene            7289..8542
                     /gene="kch"
                     /locus_tag="IRB70_003747"
     CDS             7289..8542
                     /gene="kch"
                     /locus_tag="IRB70_003747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated potassium channel protein"
                     /protein_id="HBC0633608.1"
                     /translation="MSHWATFKQTATNLWVTLRHDILALAVFLNGLLIFKTIYGMSVN
                     LLDIFHIKAFSELDLSLLANAPLFMLGVFLVLNSIGLLFRAKLAWAISIILLLIALIY
                     TLHFYPWLKFSIGFCIFTLVFLLILRKDFSHSSAAAGTIFAFISFTTLLFYSTYGALY
                     LSEGFNPRIESLMTAFYFSIETMSTVGYGDIVPVSESARLFTISVIISGITVFATSMT
                     SIFGPLIRGGFNKLVKGNNHTMHRKDHFIVCGHSILAINTILQLNQRGQNVTVISNLP
                     EDDIKQLEQRLGDNADVIPGDSNDSSVLKKAGIDRCRAILALSDNDADNAFVVLSAKD
                     MSSDVKTVLAVSDSKNLNKIKMVHPDIILSPQLFGSEILARVLNGEEINNDMLVSMLL
                     NSGHGIFSDNDEQETKADSKESAQK"
     gene            complement(8597..8770)
                     /locus_tag="IRB70_003748"
     CDS             complement(8597..8770)
                     /locus_tag="IRB70_003748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciY family protein"
                     /protein_id="HBC0633609.1"
                     /translation="MKRSRTEVGRWRMQRQASRRKSRWLEGQSRRNMRIHSIRKCILN
                     KQRNSLLFAIYNI"
     gene            8913..10373
                     /gene="cls"
                     /locus_tag="IRB70_003749"
     CDS             8913..10373
                     /gene="cls"
                     /locus_tag="IRB70_003749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBC0633610.1"
                     /translation="MTTVYTLVSWLAILGYWLLIAGVTLRILMKRRAVPSAMAWLLII
                     YILPLVGIIAYLAVGELHLGKRRAERARAMWPSTAKWLNDLKACKHIFAEENSSVAAP
                     LFKLCERRQGIAGVKGNQLQLMTESDDVMQALIRDIQLARHNIEMVFYIWQPGGMADQ
                     VAESLMAAARRGIHCRLMLDSAGSVAFFRSPWPELMRNAGIEVVEALKVNLMRVFLRR
                     MDLRQHRKMIMIDNYIAYTGSMNMVDPRYFKQDAGVGQWIDLMARMEGPIATAMGIIY
                     SCDWEIETGKRILPPPPDVNIMPFEQASGHTIHTIASGPGFPEDLIHQALLTAAYSAR
                     EYLIMTTPYFVPSDDLLHAICTAAQRGVDVSIILPRKNDSMLVGWASRAFFTELLAAG
                     VKIYQFEGGLLHTKSVLVDGELSLVGTVNLDMRSLWLNFEITLAIDDKGFGADLAAVQ
                     DDYISRSRLLDARLWLKRPLWQRVAERLFYFFSPLL"
     gene            10408..10737
                     /locus_tag="IRB70_003750"
     CDS             10408..10737
                     /locus_tag="IRB70_003750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309775.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciU family protein"
                     /protein_id="HBC0633611.1"
                     /translation="MDMDLNNRLTEDETLEQAYDIFLELAADNLDPADVLLFNLQFEE
                     RGGAELFDPAEDWQEHVDFDLNPDFFAEVVIGLADSEDGEINDVFARILLCREKDHKL
                     CHIIWRE"
     gene            complement(10790..11794)
                     /gene="oppF"
                     /locus_tag="IRB70_003751"
     CDS             complement(10790..11794)
                     /gene="oppF"
                     /locus_tag="IRB70_003751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppF"
                     /protein_id="HBC0633612.1"
                     /translation="MNAVTEGRKVLLEIADLKVHFEIKDGKQWFWQPPKTLKAVDGVT
                     LRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGHVAWLGKELLGMKPDEWRAVRSD
                     IQMIFQDPLASLNPRMTIGEIIAEPLRTYHPKMSRQEVRERVKAMMLKVGLLPNLINR
                     YPHEFSGGQCQRIGIARALILEPKLIICDEPVSALDVSIQAQVVNLLQQLQREMGLSL
                     IFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPLHPYTRALMSAVPIPDPDLE
                     KNKTIQLLEGELPSPINPPSGCVFRTRCPIAGPECAKTRPVLEGSFRHAVSCLKVDPL
                     "
     gene            complement(11791..12804)
                     /gene="oppD"
                     /locus_tag="IRB70_003752"
     CDS             complement(11791..12804)
                     /gene="oppD"
                     /locus_tag="IRB70_003752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein tripeptide/oligopeptide ABC transporter
                     ATP binding protein OppD"
                     /protein_id="HBC0633613.1"
                     /translation="MSVIETATVPLAQQQADALLNVKDLRVTFNTPDGDVTAVNDLNF
                     SLRAGETLGIVGESGSGKSQTAFALMGLLAANGRIGGSATFNGREILNLPERELNKLR
                     AEQISMIFQDPMTSLNPYMRVGEQLMEVLMLHKNMSKAEAFEESVRMLDAVKMPEARK
                     RMKMYPHEFSGGMRQRVMIAMALLCRPKLLIADEPTTALDVTVQAQIMTLLNELKREF
                     NTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNARDVFYQPVHPYSIGLLNAVPRLD
                     AEGETMLTIPGNPPNLLRLPKGCPFQPRCPHAMEICSSAPPLEEFTPGRLRACFKPVE
                     ELL"
     gene            complement(12816..13724)
                     /gene="oppC"
                     /locus_tag="IRB70_003753"
     CDS             complement(12816..13724)
                     /gene="oppC"
                     /locus_tag="IRB70_003753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000979653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppC"
                     /protein_id="HBC0633614.1"
                     /translation="MMLSKKNSETLENFSEKLEVEGRSLWQDARRRFMHNRAAVASLI
                     VLVLIALFVILAPMLSQFAYDDTDWAMMSSAPDMESGHYFGTDSSGRDLLVRVAIGGR
                     ISLMVGVAAALVAVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFF
                     GQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKEFIEAAQVGGVSTPGIVIRHIVPNV
                     LGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSPWLLLFPA
                     GFLVVTLFCFNFIGDGLRDALDPKDR"
     gene            complement(13739..14659)
                     /gene="oppB"
                     /locus_tag="IRB70_003754"
     CDS             complement(13739..14659)
                     /gene="oppB"
                     /locus_tag="IRB70_003754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter permease OppB"
                     /protein_id="HBC0633615.1"
                     /translation="MLKFILRRCLEAIPTLFILITISFFMMRLAPGSPFTGERTLPPE
                     VMANIEAKYHLNDPIMTQYFSYLKQLAHGDFGPSFKYKDYSVNDLVASSFPVSAKLGA
                     AAFFLAVILGVSAGVIAALKQNTKWDYTVMGLAMTGVVIPSFVVAPLLVMIFAIILHW
                     LPGGGWNGGALKFMILPMVALSLAYIASIARITRGSMIEVLHSNFIRTARAKGLPMRR
                     IILRHALKPALLPVLSYMGPAFVGIITGSMVIETIYGLPGIGQLFVNGALNRDYSLVL
                     SLTILVGALTILFNAIVDVLYAVIDPKIRY"
     gene            complement(14745..16376)
                     /gene="oppA"
                     /locus_tag="IRB70_003755"
     CDS             complement(14745..16376)
                     /gene="oppA"
                     /locus_tag="IRB70_003755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707150.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein OppA"
                     /protein_id="HBC0633616.1"
                     /translation="MTNITKRSLVAAGVLAALMAGNVALAADVPAGVTLAEKQTLVRN
                     NGSEVQSLDPHKIEGVPESNISRDLFEGLLVSDLDGHPAPGVAESWDNKDAKVWTFHL
                     RKDAKWSDGTPVTAQDFVYSWQRSVDPNTASPYASYLQYGHIAGIDEILEGKKPITDL
                     GVKAIDDHTLEVTLSEPVPYFYKLLVHPSTSPVPKAAIEKFGEKWTQPGNIVTNGAYT
                     LKDWVVNERIVLERSPTYWNNAKTVINQVTYLPIASEVTDVNRYRSGEIDMTYNNMPI
                     ELFQKLKKEIPDEVHVDPYLCTYYYEINNQKPPFNDVRVRTALKLGMDRDIIVNKVKA
                     QGDMPAYGYTPPYTDGAKLTQPEWFGWSQEKRNEEAKKLLAEAGYTADKPLTINLLYN
                     TSDLHKKLAIAASSLWKKNIGVNVKLVNQEWKTFLDTRHQGTFDVARAGWCADYNEPT
                     SFLNTMLSNSSMNTAHYKSPAFDSIMAETLKATDEAQRTALYTKAEQQLDKDSAIVPV
                     YYYVNARLVKPWVGGYTGKDPLDNTYTRNMYIVKH"
     gene            16660..16956
                     /locus_tag="IRB70_003756"
     CDS             16660..16956
                     /locus_tag="IRB70_003756"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633617.1"
                     /translation="MRFLLANTFCKIVKQFSFIDRIRIYSLHPCLNKHLSIQSNRGWL
                     SMSLFSDYSSSSEMHNNLTIDYYLALSSTKGSGITNIISIILQQAQDYDVAKIT"
     gene            complement(17114..17761)
                     /gene="ychE"
                     /locus_tag="IRB70_003757"
     CDS             complement(17114..17761)
                     /gene="ychE"
                     /locus_tag="IRB70_003757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAAT family transporter YchE"
                     /protein_id="HBC0633618.1"
                     /translation="MIQTLFDFPVYFKFFIGLFALVNPVGIIPVFISMTSYQTAAARN
                     KTNLTANLSVAIILWISLFLGDTILQLFGISIDSFRIAGGILVVTIAMSMISGKLGED
                     KQNKQEKSETAVRESIGVVPLALPLMAGPGAISSTIVWGTRYHSISYLFGFFVAIALF
                     ALCCWGLFRMAPWLVRVLRQTGINVITRIMGLLLMALGIEFIVTGIKGIFPGLLY"
     gene            18238..20913
                     /gene="adhE"
                     /locus_tag="IRB70_003758"
                     /gene_synonym="adhC"
     CDS             18238..20913
                     /gene="adhE"
                     /locus_tag="IRB70_003758"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBC0633619.1"
                     /translation="MAVTNVAELNALVERVKKAQREYASFTQEQVDKIFRAAALAAAD
                     ARIPLAKMAVAESGMGIVEDKVIKNHFASEYIYNAYKDEKTCGVLSEDDTFGTITIAE
                     PIGIICGIVPTTNPTSTAIFKSLISLKTRNAIIFSPHPRAKDATNKAADIVLQAAIAA
                     GAPKDLIGWIDQPSVELSNALMHHPDINLILATGGPGMVKAAYSSGKPAIGVGAGNTP
                     VVIDETADIKRAVASVLMSKTFDNGVICASEQSVVVVDSVYDAVRERFATHGGYLLQG
                     KELKAVQDVILKNGALNAAIVGQPAYKIAELAGFSVPENTKILIGEVTVVDESEPFAH
                     EKLSPTLAMYRAKDFEDAVEKAEKLVAMGGIGHTSCLYTDQDNQPARVSYFGQKMKTA
                     RILINTPASQGGIGDLYNFKLAPSLTLGCGSWGGNSISENVGPKHLINKKTVAKRAEN
                     MLWHKLPKSIYFRRGSLPIALDEVITDGHKRALIVTDRFLFNNGYADQITSVLKAAGV
                     ETEVFFEVEADPTLSIVRKGAELANSFKPDVIIALGGGSPMDAAKIMWVMYEHPETHF
                     EELALRFMDIRKRIYKFPKMGVKAKMIAVTTTSGTGSEVTPFAVVTDDATGQKYPLAD
                     YALTPDMAIVDANLVMDMPKSLCAFGGLDAVTHAMEAYVSVLASEFSDGQALQALKLL
                     KEYLPASYHEGSKNPVARERVHSAATIAGIAFANAFLGVCHSMAHKLGSQFHIPHGLA
                     NALLICNVIRYNANDNPTKQTAFSQYDRPQARRRYAEIADHLGLSAPGDRTAAKIEKL
                     LAWLETLKAELGIPKSIREAGVQEADFLANVDKLSEDAFDDQCTGANPRYPLISELKQ
                     ILLDTYYGRDYVEGETAAKKEAAPAKAEKKAKKSA"
BASE COUNT         5528 a         5130 c         4968 g         5366 t
ORIGIN      
        1 aaatcagagc gcaactgata ctctctcgtc gccagtacca gaaactgatg cagtggaaac
       61 ggcaattccg ggcaacgaaa aaaccgaatg caaagtggaa gtcgaaccat ctgtagagcg
      121 tgaggggccg ttctacttcc tcttcaccga caaggatggc gaaaaatacg gtcgcgcaaa
      181 caaactttct ggtctggaaa aagcactagc cttgggagct acggaaatca caaaagagga
      241 atacttcgca cgtaaaaacg gcacgtactc aggttcacaa caaaatactg gtgcatctga
      301 cacgaccgca caaccagagc cggtaaaagt taccgctgac gaagtaaaca aaattatgca
      361 ggcagccaat atcagccagc ctgacgccga taagttgctt gctgcctctc gcggagaatt
      421 tgttgcaggg attagcgacc cgaatgatcc gaaatgggta aaggggattg aaacccgcga
      481 ttctgtaaac cagaaccagc aagaatcgga acagaacgac cagaaagcgg aacaaaacag
      541 cccaaatacg caacaaaacg agccagaaac gaaacaacct gagccagtag cgcaacagga
      601 accggaaaaa gtctgcaccg cctgcggtca aagcggtggc ggcaactgcc ctgattgtgg
      661 cgcggtgatg ggtgacgcaa cataccagga aacattcgat gaagagaatc aggttgaagt
      721 tcaggaaaat gatccgaagg aaatggaagg cgctgaacat ccacacaagg agaatgctgg
      781 tagcgctcag gatcacgcca gcgatagtga aactggcgag acggcagatc ccttaattac
      841 gatgaacggt catcacgtta tcacatccac cagcaggacg tgtgaccatc taatgatcga
      901 ccttgaaacc atgggaaaaa atcctgatgc cccgattatc tcaataggtg caatattttt
      961 cgatccgcaa accggagata tgggaccgga atttagtaag actatcgatc tggaaactgc
     1021 tggcggagtc attgatcgtg acgtcattaa aaggtggctg aagcaatcac gtgaagcgca
     1081 gtctgccatt atgaccgatg aaatcccgtt agatgatgca ctgttacaat tgcgggaatt
     1141 tatcgacgaa aactccggtg aattttttgt tcaggtctgg ggaaatggag ccaacttcga
     1201 caacacgatt ttgcgccgtt catacgaacg gcaggggatc ccctgcccgt ggcgttacta
     1261 caacgatcgc gatgtacgca caatcgttga gctggggaaa gccatagact tcgatgccag
     1321 aacggctatt ccattcgaag gtgagcgcca taatgcactt gatgacgccc gttaccaggc
     1381 aaaatacgtt tcagttatct ggcaaaaact gatcccgaat caggctgatt tttaatgttc
     1441 aaccccggtc gttgcccacc agctatagtg gcggcgacca tgattagcga acgacgctca
     1501 tggcaagact tattctgctc actgagtggg caaaagagga attcagtgaa ccggtcccaa
     1561 ctccgagtac gttaagtaaa tacgctaaag ccggaatgat atttcctctc cccaaaaaag
     1621 ttggaagacg ctggcgagtg gatccgcaag ctcgctttgt cggaatggta aacaagccgg
     1681 aggtgatcgc cacagatcac cctgctttga agaggatact ggaagatggc gcgcccgcga
     1741 aaatataaaa ccaatgttcc gggattatct ccgtattttg acaaaagaaa taacaaagtt
     1801 tactggcgtt acaggcatcc cataacaggc aaaaatcacg gtctcggcag tattgaccag
     1861 aaactggcag aaactattgc agcagaagcg aacagccgta ttgcccggca gcaaatggaa
     1921 caaatgctca gtctgcagga gaaaattatt agtgataccg gcggttcatc aaccgttacc
     1981 atttttctga ataattacag aaaaattcaa caggaaagat atgaaaacgg cgagatcaaa
     2041 ctcaacacgc tgaaacagaa agcggcccct ctcagggtat ttgatgaacg ttttggcacc
     2101 agaccgttag atgccataac cgtaaaagat gtggtatcag tactggaaga gtacaaggcc
     2161 agaggacata acagaatggg acaaattttc aggaaggtac tgatcgatgt tttccgggaa
     2221 gctcagcaaa cgggcgatgt cccgccaggc tttaaccctg cagaatcggc aaaaaaaccg
     2281 caggtgcgga tatcaagaca gcgactgact tttgatgagt ggatgatgat ttataacgca
     2341 gcggaaaagg atggttactt tttacagcgc ggtatgctgc tggcactgat gacaggccag
     2401 cgcctttcag atatttgcaa aatgcaattt tcggatatcc gggatggtta tcttcatgtc
     2461 gaacagcaaa aaacaggaac ccggattgcc atccctctgg ctctgcgttg cgataaatta
     2521 aatctcaccc tggatgatgt ggtgtcatcc tgccgcgatt gcgttcttag tccgtggcta
     2581 ttgcaccacc atcacgcgaa agggacagct aagcgcggcg ggatggttaa gccagcaaca
     2641 ttaaccgttg catttaaaaa agcccgggat tctgtggatt acaactggcg tgctaatggc
     2701 accccaccct ctttccatga gcagagatct ttatcagagc gattgttcag agagcagggg
     2761 gttgatacca aaattttgct gggccattcg aatcaaaaaa tgaccgatat ttacaacgac
     2821 gcacgcggta aggaatggaa aaaactggtc atttgatgac cagttttgca gaggggtttt
     2881 gcagaggttt tgcagagaaa attaaaaacg atatcctgcg gagaacataa acacccacgg
     2941 atccagtcgt accgagtctt ttacggtagt aacaccagat ttgtacttag ccgtggtatc
     3001 gatatccatg taccacactg acatgttaac caaccagtca cggttaatca gataatcaac
     3061 ccccacctgc ccggcagctc cccaggaatc tttcagactg agatcggaaa gccccgcctc
     3121 tttgccatga tcgttaaatc cattatcaaa gaaggtggtg tagttaatac ctgccccaac
     3181 gtaaggacgg aatttgctgc tggcatcacc aaaataccac tgcgccatca gtgttggcgg
     3241 cagatgatga acggttgcaa tatcgccggt cgcccgggtg ccgattttat ggcggaacgg
     3301 cgtcgctgcc agcaattcca caccaatgtt atcggtcgcc atataagtaa acgtcaggcc
     3361 cagttgcgtg ttattggtca cgctgaatcc acccagactt cctaacgtac caccagcacc
     3421 ttctgttgga cgtacggttg cagaacctgc acgcataaaa aattcgcctg cttcatgcgc
     3481 aaaggcactg ccagagagaa gagttgttac tgccaaagcc gccactgtta actttttcat
     3541 atccgctccg tcgttatggt tataaaaacg tgacgaatat acctacattg gagtaacaaa
     3601 tgatcctaca tagatcacat tacatatgat aattcaccat ttattgatct ggattaattt
     3661 agaagttgca ttaagaatcc tggttaatgt gattcaaatc aatttttaaa tattttcgct
     3721 acgcaaatat taactcgatc gccacttgcc gcgatttgcc cacgtctgaa ggccagcaat
     3781 tacctccgct ttacaaagat atgcttttcc atacaagacc tgatgctgcc acccgaggct
     3841 taaccagggt acaattgccc gctaattaac acctgcataa aactcaagga gagtgcatgt
     3901 ctatcacggc gcagtccgta taccgtgaca ccggaaattt cttccgcaat caatttatga
     3961 ccattctgtt ggtatcgttg ctatgtgcgt ttatcacagt ggtgttaggg catgttttct
     4021 cacccagtga tgcacagctt gcgcagctca atgacggcgt gcccgttagc ggcagtagtg
     4081 gcttgttcga cctggttcag aatatgtcac cggaacagca acaaattttg ctgcaggctt
     4141 cagcggcgtc cactttttca ggattaatcg gtaacgccat tctcgccgga ggcgtaatat
     4201 taattatcca gctggtgtct gcgggtcaga gagtcagtgc gctgcgagct attggtgcca
     4261 gtgcgccgat attgccaaag ttatttattc tgatttttct gactaccctt ttagtacaga
     4321 ttggcatcat gctggtggtc gttccgggaa ttatcatggc cattttactg gccctggcac
     4381 cggtgatgtt ggtacaggac aaaatgggcg tttttgcctc gatgcgtagc agtatgcggc
     4441 tgacttgggc gaatatgcgt ctggtggcac ccgcagtact gagctggttg ctggcaaaaa
     4501 cactgttgct gctttttgcc tcttcttttg ccgcattaac cccggaaatt ggtgccgtac
     4561 tggcgaacac cttgagcaac ctgatttcag ccgtactgct catctatctg ttccgcctgt
     4621 atatgttgat tcgccaataa ccttaagcat ttgattacgg aatcgtaaaa tgaagcagtt
     4681 tcttgatttt ttaccgctgg ttgtcttttt cgcgttttac aagatttatg acatctatgc
     4741 ggctactgcg gcgctgatcg tcgccacggc gattgtgctt atatatagct gggttcgctt
     4801 tcgtaaggtt gagaagatgg ccctgatcac ttttgttctg gtggtcgtct tcggtggctt
     4861 gaccctgttc ttccacaatg atgagtttat taaatggaag gttactgtca tttatgccct
     4921 gtttgcaggt gccctgttag tcagccaatg ggtgatgaaa aagccgctaa ttcagcggat
     4981 gctgggtaaa gaactcaccc tgccgcaacc ggtatggtcg aagctgaatc tggcctgggc
     5041 tgttttcttt atcctttgcg gtctggcaaa catctacatc gcattctggc tgccgcaaaa
     5101 tatttgggtc aactttaaag tctttggcct gaccgccctt accttaatct tcacattgtt
     5161 aagcggtatc tatatctacc gccacatgcc gcaggaagat aaatcctaac cagactgcca
     5221 gtccttcggg gctggcgctg tatctcctct gttctcctca ggaaaatcat agtagcatcg
     5281 cgcctgtgat tttcctttta agtcggtttt accatgtcta caacacataa cgtccctcag
     5341 ggcgatcttg ttttacgtac tttagccatg cccgccgata ccaatgccaa tggtgacatc
     5401 tttggtggtt ggttaatgtc acaaatggat attggcggcg ctattctggc gaaagaaatt
     5461 gcccacggtc gtgtagtgac cgtgcgggtt gaaggaatga ctttcttacg gccggttgcg
     5521 gtcggcgatg tggtgtgctg ctatgcacgc tgtgtccaga aagggacgac atcagtcagc
     5581 attaatattg aagtgtgggt gaaaaaagtg gcgtctgaac ccatcgggca acgctataaa
     5641 gcaacagaag cattatttaa gtatgtcgcg gttgatcccg aaggaaaacc tcgcgcctta
     5701 cctgttgagt aataatcaaa agcctccggt cggaggcttt tgactttctg tttactgaat
     5761 ttcggtggtg ccgttaattt taaacaggat attcaccaca atcccactgc ctggcttacc
     5821 cggctcataa cgccatctgc gcatcgcatt tttcacctca cgctcaaaca tgtttgcagg
     5881 cttggctgag aggatttgta cgttatccac gcgaccatct ggcgtgacat caaatttaac
     5941 tttaacctgc ccttcaatgc gcaatgcctg tgctcgtgcc ggatactgcg gctgattacg
     6001 gcttaatgcg cgtggtcctg aagccacact ggtaaccggc ttgctggttg cagccgttgc
     6061 cgtacttgat gtcgggcgcg cgggtgccgt attttcaaac ggtgatgccg gacgcgactc
     6121 tacgggtttg acatcgcgtt ttggctgctc cacctttttc accggcttcg gttttggctt
     6181 aggtttcggc ttcggctttt caatgaccac cggagcttct tttggcggtt cagggatcgg
     6241 ctcaggttcc ggttctggct ctaccaccgg ctccggtggt ggttgaacgg cttgtggcgg
     6301 ttcgagatcc gctggcgcaa ccatcgtgac agaaatcggc tgcgcgggcg caggtagttc
     6361 aataacctga tgtaccgagg tatagagcag acccgccaca acagcaccat gaatgcagac
     6421 cgaaagtaac gtcggccagg ggaagcggcg aggtaaatca agggtcattg aagtcataat
     6481 catttcagta gaaaaaccag gcctcgattt taaatgcaaa tagcaatcat attcaataag
     6541 gcaagacgat caggatcagt gaaaatgtca tttttggcgc aattgacctt actttttaaa
     6601 tggtcttaac aaagacatca tctttccgtt gcagatcttc gccctttcaa ataacgtact
     6661 ttacaacttt cccgaacaag gagttgtgcc cgtgttgtat gttatttacg ctcaagacaa
     6721 agctgatagc ctcgaaaaac gcctttccgt tcgtccggca catttagcac gtttacagtt
     6781 actgcatgat gaaggtcgtt tgttgaccgc cggtccaatg ccagcagtag acagtaacga
     6841 tccaggggct gcgggattta ctggctcaac cgttattgct gaatttgaat cgctggaagc
     6901 agctcaggcc tgggccgatg ctgacccgta cgtagcggca ggagtctatg aacacgtttc
     6961 agtgaaacca tttaagaaag tgttctgaat agagattcaa tatttaaggg cacggttttt
     7021 gcaaccgtgt tcttgtttgg cctttcctta taggtcggtc agtgcattca cccccacaag
     7081 cagataataa ctttatctgt atttctttat atgatgtgag catattcagg aaaaatgccc
     7141 tttcctgacg cagagttgct cactcaaaac ctttgattac ttcagataaa gtcatctact
     7201 attgtttaac acattcacgt gctgcatgta tgttcagaaa atgtgcacgt tgagataatt
     7261 aaacaaaatt gtggttacag aggtatcagt gagtcactgg gctacattca aacaaacagc
     7321 aactaattta tgggtgaccc tacggcacga cattctcgcg ctggccgttt ttttaaatgg
     7381 attgcttatt tttaaaacaa tctatggtat gtcggtcaat ttgcttgata ttttccatat
     7441 caaagccttt tcagagttgg atctctcctt gctggcaaac gccccactct ttatgctcgg
     7501 cgtctttctt gtcctgaact ccattggctt actgttccgg gcaaaactcg catgggcaat
     7561 cagtatcatt ttgttgttga tagcgctaat ttacaccctg catttttatc cctggctgaa
     7621 atttagtatt ggattttgca tttttacgct ggtgtttttg ctgatactgc gcaaagactt
     7681 ctcccacagt agcgccgcag ccgggacaat tttcgcattt attagtttca cgacgttact
     7741 gttttactcc acctacggtg cgctttattt aagcgaaggt tttaatccgc gaatagaaag
     7801 tttgatgacc gcgttctatt tttcgataga aaccatgtca accgtcggct atggcgatat
     7861 tgtccctgtt tctgaatcag cacgattgtt cactatttcg gtcattattt ccggcattac
     7921 cgtttttgcc acctctatga cctcaatttt tggtccgctt atccgcgggg gattcaacaa
     7981 acttgtaaaa ggaaacaatc atacaatgca tcgtaaagat cattttattg tttgcggaca
     8041 ttcgattctc gccatcaata cgatcctgca actgaatcaa cgcggacaaa acgttacggt
     8101 tatcagcaac ttgcctgaag atgatatcaa gcaacttgag caacgcttag gcgataacgc
     8161 tgatgttatc cccggtgaca gtaatgacag ttcagtgtta aagaaagcgg gaatcgatcg
     8221 ttgccgggcc attctggcgc tgagtgataa cgatgcagat aacgcgtttg ttgtactctc
     8281 ggcaaaagat atgagcagtg atgtcaaaac agttcttgcc gtcagtgata gcaaaaacct
     8341 gaataagatt aagatggtac atccggatat cattctctca ccacaactgt ttggcagcga
     8401 aattctggcg cgagttttaa atggtgaaga gattaataat gatatgctcg tttcaatgtt
     8461 gttgaactcc ggtcatggca ttttcagcga taacgatgaa caagaaacga aagctgacag
     8521 taaagaatcg gcgcaaaaat agagtttaaa gacggaagag taaacttatt gggcaccgca
     8581 atggtgccca gaacatttag atattgtaga tcgcaaacaa taacgagtta cgctgtttgt
     8641 ttagaatgca cttcctgatg ctgtggatac gcatatttcg gcgcgactgc ccctcaagcc
     8701 aacgcgattt acgtcggcta gcctgacgct gcatgcgcca gcgccccact tccgttctac
     8761 tccgcttcat gttaactact ctatgcaata acagaatggt cattataccc ccgcccccga
     8821 cgctgaccag tgcttttccc gcgtttttat ttgccagatg aatccatatg cgtaaactca
     8881 taacaatgcg ctttcaaaag gatttctaat ctatgacaac cgtttatacg ttggtgagtt
     8941 ggttggccat tctgggatac tggttgctca ttgcaggcgt aactttacgc attctaatga
     9001 aacgacgcgc agttccctcc gcgatggcct ggctgttgat tatttacatt ctgccgttag
     9061 tcggaattat tgcctatctt gccgttggcg agctccattt aggcaaacgc cgcgctgagc
     9121 gcgccagagc gatgtggcct tccaccgcaa aatggcttaa cgaccttaaa gcctgtaagc
     9181 atatcttcgc cgaagaaaat agcagtgtcg ctgcgccatt attcaagctt tgcgagcgtc
     9241 gtcaggggat cgcaggggtc aaagggaatc agctacaact gatgaccgag tcagatgatg
     9301 tgatgcaggc gttaatccgc gacatccagc tcgcgcgcca taatattgag atggtgtttt
     9361 atatctggca gcccggcggc atggcggacc aggtggctga atcattaatg gccgctgcac
     9421 ggcgcggtat tcattgccga ttgatgctcg actccgccgg gagtgtggct tttttccgca
     9481 gcccgtggcc cgagctaatg cgtaatgccg gtattgaagt ggtcgaagcc ttaaaggtca
     9541 atctgatgcg tgtgttttta cgccgtatgg acctgcgcca acatcgcaag atgatcatga
     9601 tcgataatta catcgcgtac accggcagca tgaatatggt cgaccctcgc tacttcaaac
     9661 aagatgcggg cgtagggcaa tggattgatc tgatggcgcg tatggaaggc cccatcgcca
     9721 ccgcgatggg gattatttat tcctgcgact gggagattga aaccgggaaa cgtattctgc
     9781 cgccgccacc agatgtcaat attatgccgt ttgagcaggc cagcggtcac accattcaca
     9841 caattgcttc tggccccggc tttccggaag atctcattca ccaggcatta ttgactgctg
     9901 cttattcggc tcgtgaatat ttgatcatga caacgcccta ttttgtgccc agcgatgatt
     9961 tacttcatgc gatttgcacg gcggcgcagc gcggggtgga tgtcagtatt atccttccgc
    10021 gaaaaaatga ctcgatgctg gtcggctggg ccagtcgcgc attctttacg gaactgctgg
    10081 ctgctggggt taaaatttat cagtttgaag gcgggttact gcataccaag agcgtgctgg
    10141 tcgatggtga actaagtctg gttggcaccg ttaaccttga tatgcgtagt ctgtggctaa
    10201 atttcgagat taccctggca atcgacgata aaggttttgg tgcagacctc gccgccgttc
    10261 aggacgatta tatttcgcgt tctcgtctgc tcgatgcccg tttatggcta aaacgtccat
    10321 tatggcaacg tgtcgccgag cgactgtttt acttcttcag cccgttgctg taaaacgtcg
    10381 ccaacagagg ttaaacaggt agtgactatg gatatggatt taaacaatcg cctgactgaa
    10441 gatgaaacgc ttgagcaggc ctacgatatt tttctcgaac tggctgccga caatctcgat
    10501 ccagctgatg ttctgctgtt caatcttcag tttgaagagc gcggcggcgc ggagttattc
    10561 gatccggcag aagactggca ggaacatgtt gatttcgatt tgaacccgga cttttttgcc
    10621 gaagtggtga ttggtctggc ggacagtgaa gatggtgaaa tcaacgatgt tttcgcgcgt
    10681 attctgttat gccgcgaaaa agatcacaaa ctttgccata tcatctggcg ggaataaata
    10741 atcgcttttg gagtgaaaaa gggctgacaa ctgtcagccc ttattgtgtt taaagcggat
    10801 cgactttcag gcaagaaacg gcgtgtctga aactcccctc cagcacagga cgtgttttgg
    10861 cacactccgg accggcaatc ggacaacggg tacggaaaac acaaccggaa ggcgggttga
    10921 tcggcgacgg taattcccct tccagtaact ggatggtttt gttcttctcc agatccggat
    10981 caggtatggg gactgccgac atcaatgccc tggtgtaagg atgtagtgga ttgtggtaga
    11041 cctcatcata ggtccccagt tctaccgcat ggccgagata catcactaac acacgatcgg
    11101 aaatgtgttt taccacggcc aggtcgtgag cgataaaaat taatgacaat cccatctcac
    11161 gttgtaactg ctggagcagg ttgaccacct gcgcctgaat tgacacatcc agcgccgaca
    11221 ccggctcatc acagataatc agcttcggtt caagaataag tgcacgtgca atcccgatac
    11281 gctggcactg cccaccagag aactcatgcg gatagcggtt aatcaggtta ggcaataacc
    11341 cgactttcag catcatcgcc ttcacgcgct cgcgaacttc ctggcgtgac attttcggat
    11401 gataagtacg cagtggttca gcgatgatct cgccgatggt catacgcggg ttcagcgatg
    11461 ccaacggatc ctggaaaatc atctgaatat cactgcgaac ggcacgccat tcatcgggct
    11521 tcatgcccag caactcttta cctaaccagg caacatgacc gtcggtcgcc ttgaccaaac
    11581 cgatgatggc gcgagcaaag gtggacttac cgcatcccga ttcccctacc acacctaatg
    11641 tttccccttc atacaggcga agagttacac catcgacggc tttgagcgtt ttcggcggtt
    11701 gccagaacca ctgtttgcca tctttgattt caaagtgcac tttcagatcg gcgatttcga
    11761 ggaggacttt tcttccttcg gttacagcat tcataacagt tcctccaccg gtttaaagca
    11821 agcacgcaga cggccaggcg taaactcttc cagcggcggt gcgctactac aaatttccat
    11881 cgcatgcgga caacgtggct ggaacgggca acctttcggt aatcgcagca ggtttggcgg
    11941 attacccgga atagtcaaca ttgtttcacc ttccgcatcg agacgcggca ccgcgttgag
    12001 caaaccgata gaataaggat gaacgggttg ataaaagaca tcgcgcgcgt tgccatattc
    12061 catcgtgcgc ccggcgtaca ttaccagcac tttgtcgcag atccccgcca ccacgccaag
    12121 atcgtgggtg atcataatga tggcggtatt aaattcccgc ttcagttcat tcaatagcgt
    12181 catgatctgc gcctgtacgg tgacgtccag cgcagtagtg ggttcatccg caatcagcag
    12241 cttaggtcga catagcaatg ccatcgcaat catgactcgc tgacgcatgc cgccagaaaa
    12301 ttcgtgcggg tacattttca tgcgtttacg cgcttccggc atttttaccg catcgagcat
    12361 ccgcaccgac tcttcaaacg cctcagcttt gctcatgttc ttatgcagca tcagcacttc
    12421 catcaactgc tcaccgacgc gcatataggg attcaacgaa gtcattgggt cctgaaaaat
    12481 cattgagatt tgttcagctc gcagtttatt gagttcacgc tctggcaaat tgaggatttc
    12541 acgcccattg aaggttgccg atccgccaat acgtccgttg gcagccaaca ggcccatcaa
    12601 cgcaaatgcg gtttgcgatt tgcccgaacc agactcacct acgatgccca gcgtttctcc
    12661 ggcacgtagg gaaaaattca gatcattgac cgccgtgacg tcgccgtccg gggtattaaa
    12721 ggtgacacgc aaatctttca cgttcagcag tgcgtcagcc tgttgttgtg cgagcggcac
    12781 agttgcagtt tcaattacgc tcatggctgc actccttaac gatctttcgg gtcgagggca
    12841 tcacgcaagc catcgccgat aaagttgaaa caaaatagcg tcaccacgag gaatcccgct
    12901 gggaacaaca gtaaccatgg agagacttcc atcgagttcg cgccatcact cagcaatgcg
    12961 ccccagctgc ttaacggctc ttgcgtcccc aaccccagga agctaaggaa agattcaaag
    13021 aggatcatgc tgggcaccaa tagcgatgcg tagaccacca ccacaccgag tacgttcggc
    13081 acaatgtggc gaataacaat gcccggcgtc gatacaccgc caacttgtgc cgcctcaata
    13141 aactctttgc gcttcagact cagggtttgc ccacgcacaa tacgagccat atccagccag
    13201 gaaaccatgc caatcgccac gaaaatcagc aggatgtttt gaccgaaaaa ggtcaccagc
    13261 aaaatgacga agaacatgaa tgggaaggag ttgaggattt ccagcagacg catcattacc
    13321 gaatccactt taccgcccag ataaccggaa agcgaaccat aaagtgtccc cacgaccact
    13381 gccaccagtg ccgcagcaac accgaccatg agtgagatac gcccgccaat cgcaacgcgc
    13441 acaagcaggt cgcgaccaga tgagtcagta ccaaagtagt gaccggactc catatccggg
    13501 gcgctggaca tcatcgccca gtcagtatcg tcataggcaa actgcgaaag catcggtgcc
    13561 aggatgacaa ataacgcgat cagcaccagc actatcagac tggcaaccgc cgcacggtta
    13621 tgcataaaac gtcgacgtgc gtcctgccac aagctgcgcc cttcgacctc cagcttttca
    13681 ctgaaatttt ccagcgtctc gctgtttttc ttacttaaca tcatcgcgag ctccagtatc
    13741 agtaacggat tttcgggtcg ataaccgcat atagcacatc gacaatggca ttaaacaaaa
    13801 tggttaaagc accaaccagg atggtcaggc ttaacactaa ggaatagtca cggttcaatg
    13861 caccattaac gaacaattgc ccaatccccg gcaaaccata aatggtttcg atgaccatag
    13921 aaccggtaat aatgccgaca aatgcagggc ccatatagga gagcacgggt aacagagcag
    13981 gttttaatgc gtggcgtaaa atgatccgcc gcataggtaa ccctttcgcc cgggcagtac
    14041 gaataaagtt ggagtgtaat acttcaatca tagagccacg ggtaatacgc gcaatactgg
    14101 cgatataggc gagtgacaac gccaccattg gcagtatcat gaatttaagc gcaccaccat
    14161 tccagccacc gcccggcagc caatgcaaaa tgatcgcaaa tatcatgact aataatggcg
    14221 caaccacaaa actggggata acaaccccgg tcattgccag ccccatcacg gtatagtccc
    14281 atttggtgtt ttgttttaat gcggcaataa cgccagcact aacacccagt attaccgcaa
    14341 ggaaaaatgc tgcggctccc agtttggcag aaacgggaaa actggatgca accaggtcat
    14401 tgaccgaata atctttatat ttaaacgatg gaccgaaatc gccatgcgcc agttgtttca
    14461 ggtagctgaa atactgtgtc atgatcggat cattaagatg atatttcgct tcgatattgg
    14521 ccatcacttc cggtggtaaa gtacgttcgc cggtaaaagg actgcccggc gcgaggcgca
    14581 tcatgaagaa cgaaatagta ataagaataa atagcgtcgg aatcgcttcc agacagcgac
    14641 gtagaataaa ttttaacatt gccctacctt ctggcctgtg ccttctgtaa tgcgataaaa
    14701 atcagacacc gtggagcagg atacgcctgc cccacgtatt gccattagtg cttcacaatg
    14761 tacatattcc gggtgtaggt attatccagc ggatctttgc cggtatagcc accaacccac
    14821 ggtttcacca gacgcgcatt cacgtagtaa taaacaggaa caatggccga atccttatcc
    14881 agctgttgtt ctgctttagt gtacagagct gtgcgctgcg cctcgtcagt cgctttcagc
    14941 gtttccgcca taatgctgtc aaaggccggg ctcttataat gcgcggtatt catcgagctg
    15001 ttcgacagca tggtgttcag gaaggaagtt ggttcgttgt agtctgcaca ccagcctgca
    15061 cgggccacat caaaagtgcc ctggtgacgg gtgtcgagga acgttttcca ctcctggtta
    15121 accagtttga cgtttacacc aatgtttttc ttccacaatg aagaggcagc aatcgccagc
    15181 tttttatgca gatcggaggt gttatacaac aggttgatgg tcaacggttt gtctgcggta
    15241 taacccgctt cagccagcag ttttttcgct tcttcgttac gtttttcctg gctccagcca
    15301 aaccattccg gctgagtcaa ttttgcgcca tcagtatatg gtggagtgta accataggcg
    15361 ggcatgtcgc cctgcgcttt cactttatta acaatgatat cgcggtccat acccaatttc
    15421 agtgcggtac gcacacgcac gtcattaaat ggcggtttct ggttgttaat ttcgtaatag
    15481 taagtgcaca ggtatggatc aacgtgaact tcgtccggga tctctttttt cagcttctgg
    15541 aacaattcga tcggcatgtt gttataagtc atgtcgattt caccactacg gtagcggttg
    15601 acatcggtaa cttcagaagc aataggcaaa taggttacct ggttaataac ggttttcgcg
    15661 ttgttccagt aggtcgggct gcgttcaaga acgattcgtt cgtttacgac ccaatctttt
    15721 aaggtatagg caccgttggt gacgatatta ccaggctggg tccatttttc gccgaatttc
    15781 tcgatagcgg cttttggcac cggtgaagtt gatgggtgaa caagtaattt atagaagtac
    15841 ggaacaggtt cacttaaggt gacttctaat gtgtgatcat caatagcttt cacgccgaga
    15901 tcggtaatcg gttttttccc ttcaagaatt tcatcaatac cggcgatatg cccatattgc
    15961 agataactgg catacggaga agcagtgttt ggatcaacag aacgttgcca gctatacaca
    16021 aagtcttgtg ctgtaactgg cgtgccatca gaccatttcg catctttacg caaatggaag
    16081 gtccagactt tcgcgtcttt attatcccag gattcagcga cgccaggtgc cggatgaccg
    16141 tcaagatcgc taaccagtaa gccttcaaac aggtctcggc tgatattaga ctccggaaca
    16201 ccttcaattt tgtgcggatc taatgactga acttctgaac cattgttacg taccagcgtt
    16261 tgtttttccg ccagtgtgac acctgcgggt acatcagctg ccagcgcgac attccctgcc
    16321 ataagcgcag ccaaaacgcc agctgctact aaacttctct tggtgatgtt ggtcattgtt
    16381 ttttggactc cctcattata attactggta ttaaccagca tgtgtaatcc cggattggga
    16441 ccctgcacag gctcggagac tttctgctgt caggttactt tatcgttacg tattactatc
    16501 accgacttta tttattctgg tgattcagac gatcacctta tgtcgattcg tactgtgtct
    16561 cccctgtcga gacacattat tctttcgcga cgatctttaa ttgttaatta ttctcattac
    16621 caataaagaa tcgcctggcg gttgcccgga aagtaccaaa tgcggttctt actcgccaat
    16681 acattttgca aaattgttaa gcaattctct tttattgacc gtatcagaat ctatagcttg
    16741 catccatgcc ttaacaaaca tctttcaatt caatcaaata gaggttggtt aagcatgtct
    16801 ctcttttctg attacagttc cagtagtgaa atgcacaata atttaacaat tgattattat
    16861 ttagcacttt cctctaccaa aggtagtgga attactaata tcatttcaat tattcttcag
    16921 caagcccagg attatgatgt ggcgaaaata acatgatggt gaggagaagc agttagggaa
    16981 atccttataa ctaactgtaa tttgagaaga atatttttac ctattccttt tgcttttgat
    17041 aactgcgcgg gaacaaagta aaaataatga cgaagtaaac ggagcatggc agctccgttt
    17101 caattgaaag gaattaataa agcaggccgg ggaaaatccc cttaatacca gtaacgataa
    17161 attcaatccc caatgccatc agcaatagcc ccataatacg cgtaatcacg ttgatgccgg
    17221 tctggcgtaa aacccgtacc agccacggtg ccatgcggaa caatccccag caacataaag
    17281 cgaacaaagc aatagccaca aagaaaccaa acagatagct aatgctgtga taacgcgtac
    17341 cccagacgat ggtagaactg atcgcccctg gccccgccat caacggcaac gccaacggca
    17401 ccacaccaat gctttcacgt accgcggttt ctgatttttc ttgcttgttc tgtttatcct
    17461 caccaagctt gccgctgatc atcgacatcg ctattgtcac caccaggatg cccccggcga
    17521 tacggaatga atcaattgat ataccaaaaa gttgtagaat cgtgtcgccg agaaaaagcg
    17581 agatccacaa gataatggcc acagacaggt tggctgtaag gttagttttg tttcgcgctg
    17641 ccgctgtctg ataactggtc atgctgataa agacgggaat aatccctacc gggttgacca
    17701 gcgcaaataa cccgatgaaa aatttgaagt aaacgggaaa atcaaaaagg gtctgaatca
    17761 cggttagctc cgaagcaaaa gccggataat gttagccata aataaggtta aaaagacgcg
    17821 ctgacaatac gccttttgac agcatttttc acctcctaac tacttaaaat tgctatcatt
    17881 cgttattgtt atctagttgt gcaaaacatg ctaatgtagc caacaaatca tactacaatt
    17941 tattaactgt tagctataat ggcgaaaagc gatgctgaaa ggtgtcagct ttgcaaaaat
    18001 ttgatttgga tcacgtaatc agtacccaga agtgagtaat cttgcttacg ccacctggaa
    18061 gtgacgcatt agagataata actctaatgt ttaaactctt ttagtaaatc acagtgagtg
    18121 tgagcgcgag taagcttttg atttccatcg gttaagcaaa tcatcaccgc actgactata
    18181 ctctcgtatt cgagcagatg atttactaaa aaagtttaac attatcagga gagcattatg
    18241 gctgttacta atgtcgctga acttaacgca ctcgtagagc gtgtaaaaaa agcccagcgt
    18301 gaatatgcca gtttcactca agagcaagta gacaaaatct tccgcgccgc cgctctggct
    18361 gctgcagatg ctcgaatccc actcgcgaaa atggccgttg ccgaatccgg catgggtatc
    18421 gtcgaagata aagtgatcaa aaaccacttt gcttctgaat atatttacaa cgcctataaa
    18481 gatgaaaaaa cctgtggtgt tctgtctgaa gacgacactt ttggtaccat cactatcgct
    18541 gaacccatcg gtattatttg cggtatcgtt ccgaccacta acccgacttc aactgctatc
    18601 ttcaaatcgc tgatcagcct gaagacccgt aacgccatta tcttctcccc gcacccgcgt
    18661 gcaaaagatg caaccaacaa agcagctgat atcgttctgc aggctgctat cgctgccggt
    18721 gctccgaaag atctgatcgg ctggatcgat caaccttcgg ttgaactgtc taacgcactg
    18781 atgcaccacc cagacatcaa cctgatcctc gcgactggtg gtccgggcat ggttaaagcc
    18841 gcatacagct ccggtaaacc agctatcggt gtaggcgcgg gtaacacgcc tgttgttatc
    18901 gatgaaactg ctgatatcaa acgtgcagtt gcatctgtgc tgatgtccaa aaccttcgac
    18961 aacggcgtaa tctgtgcttc tgaacagtct gttgttgttg ttgactctgt ttatgacgca
    19021 gtacgtgaac gtttcgcaac ccacggcggc tatctgttgc agggtaaaga gctgaaagct
    19081 gttcaggatg ttatcctgaa aaacggtgcg ctgaacgcgg ctatcgttgg tcagccagcc
    19141 tataaaattg ctgaactggc aggcttctct gtaccagaaa acaccaagat tctgatcggt
    19201 gaagtgaccg ttgttgatga aagcgaaccg ttcgcacatg aaaaactgtc cccaactctg
    19261 gcaatgtacc gcgctaaaga tttcgaagac gcggtagaaa aagcagagaa actggtagct
    19321 atgggcggta tcggtcatac ctcttgcctg tacactgacc aggataacca accggctcgc
    19381 gtttcttact tcggtcagaa aatgaaaacc gctcgtatcc tgattaacac cccggcttct
    19441 cagggtggta tcggtgacct gtataacttc aaactcgcac cttccctgac tctgggttgt
    19501 ggttcctggg gtggtaactc catctctgaa aacgttggtc cgaaacacct gatcaacaag
    19561 aaaaccgttg ctaagcgagc tgaaaacatg ttgtggcaca aacttccgaa atctatctac
    19621 ttccgccgtg gctctctgcc aatcgcgctg gatgaagtga ttactgatgg ccacaaacgt
    19681 gcgctcatcg tgactgaccg cttcctgttc aacaatggtt atgctgatca gatcacttcc
    19741 gtactgaaag cagcaggcgt tgaaactgaa gtcttcttcg aagtagaagc tgacccgacc
    19801 ctgagcatcg ttcgtaaagg tgcagaactg gcaaactcct tcaaaccaga cgtgattatc
    19861 gcgctgggtg gtggttcccc gatggacgcc gcgaagatca tgtgggtcat gtacgaacat
    19921 ccggaaactc acttcgaaga actggcgctg cgctttatgg atatccgtaa acgtatctac
    19981 aagttcccga aaatgggcgt gaaagcgaaa atgatcgctg tcaccaccac ttctggtaca
    20041 ggttctgaag tcactccgtt tgcggttgta actgacgacg ctactggtca gaaatatccg
    20101 ctggcagact atgcgctgac cccggatatg gcgattgtcg atgccaacct ggttatggac
    20161 atgccgaagt ccctgtgtgc tttcggtggt ctggacgcag taactcacgc catggaagct
    20221 tatgtttctg tactggcatc tgagttctct gatggtcagg ctctgcaggc gctgaaactg
    20281 ctgaaagaat atctgccagc gtcctaccac gaaggatcta aaaatccggt agcgcgtgaa
    20341 cgtgttcaca gtgcagcaac tatcgcgggt atcgcgtttg cgaacgcctt cctgggtgta
    20401 tgtcactcaa tggcgcacaa actgggttcc cagttccata ttccgcacgg tctggcaaac
    20461 gccctgctga tttgtaacgt tattcgctac aacgcgaacg acaacccgac caagcagact
    20521 gcattcagcc agtatgaccg tccgcaggct cgccgtcgtt atgctgaaat tgctgaccac
    20581 ctgggtctga gcgcaccggg cgaccgtact gctgctaaga tcgagaaact gctggcatgg
    20641 ctggaaacgc tgaaagctga actgggtatt ccgaaatcta tccgtgaagc tggcgttcag
    20701 gaagcagact tcctggcgaa tgtggataaa ctgtctgaag atgcattcga tgaccagtgc
    20761 accggcgcta acccgcgtta cccactgatc tccgagctga aacagattct gctggatacc
    20821 tactacggtc gtgattatgt agaaggtgaa actgcagcga aaaaagaagc cgctccggct
    20881 aaagctgaga aaaaagcgaa gaaatccgct taatcagtag cgctgtctgg caacataaac
    20941 ggtcccttct ggggtaatgc cagtcagtta agcaactgac tggctctttt tc
//
LOCUS       DADXDL010000090        20758 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.090, whole genome shotgun sequence.
ACCESSION   DADXDL010000090 DADXDL010000000
VERSION     DADXDL010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20758)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20758)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20758
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.090"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            32..475
                     /gene="cmtB"
                     /locus_tag="IRB70_003759"
     CDS             32..475
                     /gene="cmtB"
                     /locus_tag="IRB70_003759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IIA"
                     /protein_id="HBC0633620.1"
                     /translation="MRLIDYFPKSSISVIHSAKDWQEAIDFSMVSLLDKNYISENYIQ
                     AIKGSTINNGPYYILAPGVAMPHARSECGALKTGMSLTLLKQSVYFPGNDEPIKLLIG
                     LSAADANSHIGAIQALSELLCEEEILEQLLTASSEKQLADIISRG"
     gene            503..1891
                     /gene="cmtA"
                     /locus_tag="IRB70_003760"
     CDS             503..1891
                     /gene="cmtA"
                     /locus_tag="IRB70_003760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICB"
                     /protein_id="HBC0633621.1"
                     /translation="MENKSARAKVQAFGGFLTAMVIPNIGAFIAWGFITALFIPTGWL
                     PNEHFAKIVGPMITYLLPVMIGSTGGHLVGGKRGAVMGGIGTIGVIVGAEIPMFLGSM
                     IMGPLGGLVIKYIDKSLEKRIPAGFEMVINNFSLGIAGMLLCLLGFEVIGPAVLIANT
                     FVKECIEALVHAGYLPLLSVINEPAKVLFLNNAIDQGVYYPLGMQQASVNGKSIFFMV
                     ASNPGPGLGLLLAFTLFGKGMSKRSAPGAMIIHFLGGIHELYFPYVLMKPLTIIAMIA
                     GGMSGTWMFNLLDGGLVAGPSPGSIFAYLALTPKGSFLATIAGVTVGTLVSFAITSLI
                     LKMEKTVETESEDEFAQSANAVKAMKQEGAFSLSRVKRIAFVCDAGMGSSAMGATTFR
                     KRLEKAGLAIEVKHYAIENVPADADIVVTHASLEGRVKRVTDKPLILINNYIGDPKLD
                     TLFNQLTAEHKH"
     gene            1906..3183
                     /locus_tag="IRB70_003761"
     CDS             1906..3183
                     /locus_tag="IRB70_003761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
                     /protein_id="HBC0633622.1"
                     /translation="MKTKVAAIYGKRDVRLREFELPEITDNELLVSVISDSVCLSTWK
                     AALLGSEHKRVPDDLENHPVITGHECAGVIVEVGKNLTDKYKKGQRFVLQPAMGLPGG
                     YSAGYSYEYFGGNATYMIIPEIAINLGCVLPYHGSYFAAASLAEPMCCIIGAYHANYH
                     TTQYVYEHRMGVKPGGNIALLACAGPMGIGAIDYAINGGIQPSRVVVVDIDDKRLAQV
                     QKLLPVELAASKGIELVYVNTKGMSDPVQKLRALTGDVGFDDIFVYAAVPAVVEMADE
                     LLAEDGCLNFFAGPTDKNFKVPFNFYNVHYNSTHVVGTSGGSTDDMKEAIALSATGQL
                     QPSFMVTHIGGLDAVPETVLNLPDIPGGKKLIYNGVTMPLTAIADFAEKGKTDPLFKE
                     LARLVEETHGIWNEQAEKYLLAQFGVDIGEAAQ"
     gene            3180..4145
                     /gene="yggF"
                     /locus_tag="IRB70_003762"
     CDS             3180..4145
                     /gene="yggF"
                     /locus_tag="IRB70_003762"
                     /EC_number="3.1.3.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphatase"
                     /protein_id="HBC0633623.1"
                     /translation="MMSLAWPLFRVTEQAALAAWPQTGCGDKNKIDGLAVTAMRQALN
                     DVAFRGRVVIGEGEIDHAPMLWIGEEVGKGDGPEVDIAVDPIEGTRMVAMGQSNALAV
                     MAFAPRGSLLHAPDMYMKKLVVNRLAAGAIDLSLPLVDNLRNVAKALGKPLDKLRMVT
                     LDKPRLSAAIEEATQLGVKVFALPDGDVAASVLTCWQDNPYDVMYTIGGAPEGVISAC
                     AVKALGGDMQAQLIDFCQAKGDYTENRQIAEQERKRCKAMGVDVNRVYSLDELVRGND
                     ILFSATGVTGGELVNGIQQTANGVRTQTLLIGGADQTCNIIDSLH"
     gene            4167..4676
                     /gene="fumE"
                     /locus_tag="IRB70_003763"
     CDS             4167..4676
                     /gene="fumE"
                     /locus_tag="IRB70_003763"
                     /EC_number="4.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarase E"
                     /protein_id="HBC0633624.1"
                     /translation="MATLTEDDVLEQLDAQDNLFSFMKTAHSILLQGIRQFLPSLFVD
                     NDEEIVEYAVKPLLAQSGPLDDIDVALRLIYALGKMDKWLYADITHFSQFWHYLNEQD
                     ETPGFADDMTWDFISNVNSITRNATLYDALKAMKFADFAVWSEARFSGMVKTALTLAV
                     TTTLKELTP"
     gene            4673..5386
                     /locus_tag="IRB70_003764"
     CDS             4673..5386
                     /locus_tag="IRB70_003764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417403.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside/nucleotide kinase family protein"
                     /protein_id="HBC0633625.1"
                     /translation="MKIELTVNGLKIQAQYQNEEIENVHKPLLHMLAALQTVNPQRRT
                     VVFLCAPPGTGKSTLTTFWEYIAQQDPELPAIQTLPMDGFHHYNSWLDAHQLRPFKGA
                     PETFDVAKLAENLRQVVEGDCTWPQYDRQKHDPVEDALHVTAPLVIVEGNWLLLDDEK
                     WQELASFCDFSIFIHAPAQILRERLISRKIAGGLSRQEAEAFYARTDGPNVERVLMNS
                     RQANLIVEMTEEGRYYFTS"
     gene            5671..6690
                     /gene="epd"
                     /locus_tag="IRB70_003765"
     CDS             5671..6690
                     /gene="epd"
                     /locus_tag="IRB70_003765"
                     /EC_number="1.2.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="erythrose-4-phosphate dehydrogenase"
                     /protein_id="HBC0633626.1"
                     /translation="MTVRVAINGFGRIGRNVVRALYESGRRAEITVVAINELADAAGM
                     AHLLKYDTSHGRFAWEVRQERNQLFVGDDAIRVLHERSLQSLPWRELGVDVVLDCTGV
                     YGSREHGEAHIAAGAKKVLFSHPGSNDLDATVVYGVNQDQLRAEHRIVSNASCTTNCI
                     IPVIKLLDDAYGIESGTVTTIHSAMHDQQVIDAYHPDLRRTRAASQSIIPVDTKLAAG
                     ITRFFPQFNDRFEAIAVRVPTINVTAIDLSVTVKKPVKANEVNLLLQKAAQGAFHGIV
                     DYTELPLVSVDFNHDPHSAIVDGTQTRVSGAHLIKTLVWCDNEWGFANRMLDTTLAMA
                     TVAFR"
     gene            6740..7903
                     /gene="pgk"
                     /locus_tag="IRB70_003766"
     CDS             6740..7903
                     /gene="pgk"
                     /locus_tag="IRB70_003766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005761248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBC0633627.1"
                     /translation="MSVIKMTDLDLAGKRVFIRADLNVPVKDGKVTSDARIRASLPTI
                     ELALKQGAKVMVTSHLGRPTEGEYNEEFSLLPVVNYLKDKLSNPVRLVKDYLDGVDVA
                     EGELVVLENVRFNKGEKKDDETLSKKYAALCDVFVMDAFGTAHRAQASTHGIGKFADV
                     ACAGPLLAAELDALGKALKEPARPMVAIVGGSKVSTKLTVLDSLSKIADQLIVGGGIA
                     NTFIAAQGHDVGKSLYEADLVDEAKRLLTTCNIPVPSDVRVATEFSETAPATLKSVND
                     VKADEQILDIGDASAQELAEILKNAKTILWNGPVGVFEFPNFRKGTEIVANAIADSEA
                     FSIAGGGDTLAAIDLFGIADKISYISTGGGAFLEFVEGKVLPAVAMLEERAKK"
     gene            8117..9196
                     /gene="fbaA"
                     /locus_tag="IRB70_003767"
     CDS             8117..9196
                     /gene="fbaA"
                     /locus_tag="IRB70_003767"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016505616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase"
                     /protein_id="HBC0633628.1"
                     /translation="MSKIFDFVKPGVITGDDVQKVFQVAKENNFALPAVNCVGTDSIN
                     AVLETAAKVKAPVIVQFSNGGASFIAGKGVKSDVPQGAAILGAISGAHHVHQMAEHYG
                     VPVILHTDHCAKKLLPWIDGLLDAGEKHFAATGKPLFSSHMIDLSEESLQENIEICSK
                     YLERMSKIGMTLEIELGCTGGEEDGVDNSHMDASALYTQPEDVDYAYTELSKISPRFT
                     IAASFGNVHGVYKPGNVVLTPTILRDSQEYVSKKHNLPHNSLNFVFHGGSGSTAQEIK
                     DSVSYGVVKMNIDTDTQWATWEGVLNYYKANEAYLQGQLGNPKGEDQPNKKYYDPRVW
                     LRAGQTSMIARLEKAFQELNAIDVL"
     gene            9387..10247
                     /gene="mscS"
                     /locus_tag="IRB70_003768"
     CDS             9387..10247
                     /gene="mscS"
                     /locus_tag="IRB70_003768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311822.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="small-conductance mechanosensitive channel MscS"
                     /protein_id="HBC0633629.1"
                     /translation="MEDLNVVDSINGAGSWLVANQALLLSYAVNIVAALAIIIVGLII
                     ARMISNAVNRLMISRKIDATVADFLSALVRYGIIAFTLIAALGRVGVQTASVIAVLGA
                     AGLAVGLALQGSLSNLAAGVLLVMFRPFRAGEYVDLGGVAGTVLSVQIFSTTMRTADG
                     KIIVIPNGKIIAGNIINFSREPARRNEFIIGVAYDSDIDQVKQILTDIIQSEDRILKD
                     REMTVRLNELGASSINFVVRVWSNSGDLQNVYWDVLERIKREFDAAGISFPYPQMDVN
                     FKRVKEDKAA"
     gene            10386..11021
                     /gene="argO"
                     /locus_tag="IRB70_003769"
     CDS             10386..11021
                     /gene="argO"
                     /locus_tag="IRB70_003769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine exporter ArgO"
                     /protein_id="HBC0633630.1"
                     /translation="MFSYYFQGLALGAAMILPLGPQNAFVMNQGIRRQYHIMIALLCA
                     ISDLVLICAGIFGGSALLMQSPWLLALVTWGGVAFLLWYGFGAFKTAMSSNIELASAE
                     VLKQGRWKIIATMLAVTWLNPHVYLDTFVVLGSLGGQLDVEPKRWFALGTISASFLWF
                     FGLAILAAWLAPRLRTAKSQRIINLVVGCVMWFIALQLARDGIAHAQALFS"
     gene            11114..11854
                     /locus_tag="IRB70_003770"
     CDS             11114..11854
                     /locus_tag="IRB70_003770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidative stress defense protein"
                     /protein_id="HBC0633631.1"
                     /translation="MKFKVIALAALMGISGMAAQANELPDGPHIVTSGTASVDAVPDI
                     ATLAIEVNVAAKDAATAKKQADERVAQYISFLELNQIAKKDISSANLRTQPDYDYQDG
                     KSILKGYRAVRTVEVTLRQLDKLNSLLDGALKAGLNEIRSVSLGVAQPDAYKDKARKA
                     AIDNAIHQAQELANGFHRKLGPVYSVRYHVSNYQPSPMVRMMKADAAPVSAQETYEQA
                     AIQFDDQVDVVFQLEPVDQQPAKTPAAQ"
     gene            12022..12918
                     /locus_tag="IRB70_003771"
     CDS             12022..12918
                     /locus_tag="IRB70_003771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417396.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0633632.1"
                     /translation="MDIFISKKMRNFILLAQTNNIARAAEKIHMTASPFGKSIAALEE
                     QIGYTLFTRKDNNISLNKAGQELYQKLFPVYQRLSAIDNEIHNSGRRSREIVIGIDNT
                     YPTIIFDQLISLGDKYEGVTAQPVEFSENGVIDNLFDRQLDFIISPQHVSARVQELEN
                     LTISELPPLRLGFLVSRRYEERQEQELLQELPWLQMRFQNRANFEAMIDANMRPCGIN
                     PTIIYRPYSFMAKISAVERGHFLTVIPHFAWRLVNPATLKYFDAPHRPMYMQEYLYSI
                     RNHRYTATMLQHIAEDRDGTNH"
     gene            complement(12915..14393)
                     /gene="scpC"
                     /locus_tag="IRB70_003772"
     CDS             complement(12915..14393)
                     /gene="scpC"
                     /locus_tag="IRB70_003772"
                     /EC_number="2.8.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionyl-CoA:succinate CoA transferase"
                     /protein_id="HBC0633633.1"
                     /translation="METQWTRMTADEAAEIIQHNDMVAFSGFTPAGSPKALPTAIARR
                     ANEQHEAKKPYQIRLLTGASISATADDVLSDADAVSWRAPYQTSSGLRKKINQGAVSF
                     VDLHLSEVAQMVNYGFFGDIDVAVIEASALAPDGRVWLTSGIGNAPTWLLRAKKVIIE
                     LNHYHDPRVAELADIVIPGAPPRRNSVSIFHAMDRVGTRYVQIDPKKIVAVVETNLPD
                     AGNMLDKQNPMCQQIADNVVTFLLQEMAHGRIPPEFLPLQSGVGNINNAVMARLGENP
                     EIPPFMMYSEVLQESVVHLLETGKISGASASSLTISADSLRKIYDNMDYFASRIVLRP
                     QEISNNPEIIRRLGVIALNVGLEFDIYGHANSTHVAGVDLMNGIGGSGDFERNAYLSI
                     FMAPSIAKEGKISTVVPMCSHVDHSEHSVKVIITEQGIADLRGLSPLQRARTIIDNCA
                     HPMYRDYLHRYLENAPGGHIHHDLSHVFDLHRNLIATGSMLG"
     gene            complement(14417..15202)
                     /gene="scpB"
                     /locus_tag="IRB70_003773"
     CDS             complement(14417..15202)
                     /gene="scpB"
                     /locus_tag="IRB70_003773"
                     /EC_number="7.2.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311816.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA decarboxylase"
                     /protein_id="HBC0633634.1"
                     /translation="MSYQYVNVVTINKVAVIEFNYGRKLNALSKVFIDDLMQALSDLN
                     RPEIRCIILRAPSGSKVFSAGHDIHELPSGGRDPLSYDDPLRQITRMIQKFPKPIISM
                     VEGSVWGGAFEMIMSSDLIIAASTSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKEL
                     IFTASPITAQRALAVGILNHVVEVEELEDFTLQMAHHISEKAPLAIAVIKEELRVLGE
                     AHTMNSDEFERIQGMRRAVYDSEDYQEGMNAFLEKRKPNFVGH"
     gene            complement(15213..16208)
                     /gene="meaB"
                     /locus_tag="IRB70_003774"
     CDS             complement(15213..16208)
                     /gene="meaB"
                     /locus_tag="IRB70_003774"
                     /EC_number="3.6.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl Co-A mutase-associated GTPase
                     MeaB"
                     /protein_id="HBC0633635.1"
                     /translation="MINEATLAESIRRLRQGERATLAQAMTLVESRHPRHQALSTQLL
                     DAIMPFCGNALRLGVTGTPGAGKSTFLEAFGMLLIREGLKVAVIAVDPSSPVTGGSIL
                     GDKTRMNDLARAEAAFIRPVPSSGHLGGASQRARELMLLCEAAGYDVVIVETVGVGQS
                     ETEVARMVDCFISLQIAGGGDDLQGIKKGLMEVADLIVINKDDGDNHTNVAIAQHMYE
                     SALHILRHKYDEWQPRVLTCSALEKRGINEIWHAIIDFKTALTASGRLQQVRQQQSVE
                     WLRKQTEEEVLNHLFANEDFDRYYRQTLLAVKNNTLSPRTGLRQLSEFIQTQYFD"
     gene            complement(16201..18345)
                     /gene="scpA"
                     /locus_tag="IRB70_003775"
     CDS             complement(16201..18345)
                     /gene="scpA"
                     /locus_tag="IRB70_003775"
                     /EC_number="5.4.99.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylmalonyl-CoA mutase"
                     /protein_id="HBC0633636.1"
                     /translation="MSNVQEWQQLANKELSRREKTVDSLVQQTAEGIAIKPLYTEADL
                     DNLEVTGTLPGLPPYVRGPRATMYTAQPWTIRQYAGFSTAKESNAFYRRNLAAGQKGL
                     SVAFDLATHRGYDSDNPRVAGDVGKAGVAIDTVEDMKVLFDQIPLDKMSVSMTMNGAV
                     LPVLAFYIVAAEEQGVTPDKLTGTIQNDILKEYLCRNTYIYPPKPSMRIIADIIAWCS
                     GNMPRFNTISISGYHMGEAGANCVQQVAFTLADGIEYIKAAISAGLKIDDFAPRLSFF
                     FGIGMDLFMNVAMLRAARYLWSEAVSGFGAQDPKSLALRTHCQTSGWSLTEQDPYNNV
                     IRTTIEALAATLGGTQSLHTNAFDEALGLPTDFSARIARNTQIIIQEESELCRTVDPL
                     AGSYYVESLTDQIVKQARAIIQQIDEAGGMAKAIEAGLPKRMIEEASAREQSLIDQGK
                     RVIVGVNKYKLDHEDETDVLEIDNVMVRNEQIASLERIRATRDDAAVTAALNALTHAA
                     QHNENLLAAAVNAARVRATLGEISDALEAAFDRYLVPSQCVTGVIAQSYHQSEKSATE
                     FDAIVAQTEQFLADNGRRPRILIAKMGQDGHDRGAKVIASAYSDLGFDVDLSPMFSTP
                     EEIARLAVENDVHVVGASSLAAGHKTLIPELVEALKKWGREDICVVAGGVIPPQDYAF
                     LQERGVAAIYGPGTPMLDSVRDVLNLISQHHD"
     gene            complement(18549..19442)
                     /gene="argP"
                     /locus_tag="IRB70_003776"
     CDS             complement(18549..19442)
                     /gene="argP"
                     /locus_tag="IRB70_003776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator ArgP"
                     /protein_id="HBC0633637.1"
                     /translation="MKRPDYRTLQALDAVIRERGFERAAQKLCITQSAVSQRIKQLEN
                     MFGQPLLVRTVPPRPTEQGQKLLALLRQVELLEEEWLGDEQTGSTPLLLSLAVNADSL
                     ATWLLPALAPVLADSPIRLNLQVEDETRTQERLRRGEVVGAVSIQHQALPSCLVDKLG
                     ALDYLFVSSKPFAEKYFPNGVTRSALLKAPVVAFDHLDDMHQAFLQQNFDLPPGSVPC
                     HIVNSSEAFVQLARQGTTCCMIPHLQIEKELASGELIDLTPGLFQRRMLYWHRFAPES
                     RMMRKVTDALLDYGHKVLRQD"
     gene            complement(19513..20214)
                     /locus_tag="IRB70_003777"
                     /pseudo
     CDS             complement(19513..20214)
                     /locus_tag="IRB70_003777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242982.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="iron reductase"
     gene            20271..20758
                     /locus_tag="IRB70_003778"
                     /pseudo
     CDS             20271..20758
                     /locus_tag="IRB70_003778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT         5010 a         5044 c         5506 g         5198 t
ORIGIN      
        1 ctgtacccta aaaataaaat aaggataatt tatgcggctt attgattatt ttccaaaatc
       61 atcaatctca gttatacatt cagcaaaaga ttggcaggaa gctatcgatt tctcgatggt
      121 atcattgctg gataaaaact atatcagcga gaattacatt caggcaatta aaggttccac
      181 cattaacaat ggcccttatt atattctcgc accaggcgtg gcaatgcctc atgcgcgatc
      241 ggaatgtggg gcgcttaaaa ccgggatgtc tttgacgtta cttaaacaaa gcgtttattt
      301 tccggggaat gacgaaccga ttaaattact catcgggctt tctgctgccg atgccaattc
      361 gcacattggc gctattcagg cgttaagtga attactgtgc gaagaagaaa tactcgaaca
      421 actcttaacc gcatcatcag aaaaacaatt agcggacatt atcagccgcg gataattact
      481 ctctcctcta caggataata ttatggaaaa caagtctgct cgtgcaaagg tccaggcttt
      541 tgggggcttt ttgactgcaa tggtcatccc caatatcggt gcttttattg cctggggatt
      601 tataacggca ttatttattc ccaccggctg gctgccgaat gaacatttcg ccaaaattgt
      661 tggtccgatg attacctatt tattgcccgt gatgattggt tctaccggtg gtcatctggt
      721 cggcggtaaa cgcggcgcgg tcatgggcgg aattggtacg attggtgtga tcgtcggcgc
      781 tgaaatcccg atgttccttg gctcaatgat tatggggccg ctcggtggtc tggtgattaa
      841 atatatcgac aagtcgctgg aaaaacgcat acctgctggt tttgagatgg ttatcaataa
      901 cttctcatta ggtatcgcgg ggatgctcct ttgtctgctg ggttttgaag ttatcggccc
      961 ggcggtgtta attgctaata ctttcgtcaa agagtgtatt gaggcgctgg tacatgcggg
     1021 ttatctacct ttgctgtcag tcatcaatga accggcgaaa gtgcttttcc ttaataatgc
     1081 gatcgatcag ggcgtctatt atccgctggg aatgcaacag gcttcggtta acggtaaatc
     1141 catcttcttc atggtggcct ccaatccagg tcctggtctg gggctgctgc tggcgtttac
     1201 cttgtttggt aaagggatga gtaaacgttc tgcgcccggg gcgatgatta ttcacttcct
     1261 cggtgggatc cacgaactgt atttcccgta tgtgctgatg aagccgctga ccattattgc
     1321 catgattgcg ggcggtatgt ctggcacctg gatgtttaac ttactggacg gtggtctggt
     1381 ggctggccca agtccggggt ctatctttgc ttacctggca ctgacgccga aaggctcgtt
     1441 cctggcgaca attgccggtg ttacggtagg taccctggtg tcctttgcta tcacttcgct
     1501 gatactgaag atggaaaaaa cggtggaaac ggagagcgaa gatgagtttg ctcagtcagc
     1561 caatgcggtt aaggcgatga aacaagaggg ggcattctcg ttaagccggg ttaagcgtat
     1621 cgcctttgtt tgcgatgcgg ggatgggctc cagcgcgatg ggcgcaacca ccttccgtaa
     1681 acgtctggaa aaagcggggc tggcaattga agtaaaacat tacgccatag aaaacgtgcc
     1741 tgcggatgcg gatatcgtcg ttactcacgc tagtctggaa gggcgcgtga aacgtgtgac
     1801 ggataaaccg ctgatactga ttaataacta tattggcgat cccaaactcg acactttatt
     1861 taatcaatta accgccgaac ataaacactg attacagagg taaaaatgaa aaccaaagtt
     1921 gctgctattt atggcaagcg ggatgtccgt ctgcgcgaat ttgaactgcc agaaattacc
     1981 gataatgaac tgttagtgag tgtaatttct gacagcgtct gtttatcgac ctggaaagcg
     2041 gcgttactcg gtagtgaaca taaacgcgta cccgacgatt tagaaaatca tccggtcatt
     2101 accgggcatg aatgtgccgg ggttattgtt gaagtgggta aaaatctcac cgacaaatat
     2161 aaaaaaggcc agcgttttgt attgcaaccg gcgatggggt taccaggcgg atattcagcg
     2221 ggctacagct acgaatattt tggcggtaac gccacctata tgattattcc cgagatcgcc
     2281 attaacctgg gctgcgtatt accctatcac ggctcttatt ttgctgcggc gtcgctggca
     2341 gagcctatgt gctgcattat tggcgcttat catgccaatt atcacaccac gcaatatgtt
     2401 tatgagcatc gcatgggcgt caaacctggc ggcaatattg cactgctggc gtgtgctggc
     2461 ccaatgggca ttggcgctat cgattacgcc attaacggcg gtatacaacc gtcgcgggtg
     2521 gtggtggtcg atatcgacga caaacgcctg gcgcaggtac agaagctgct gccggtggag
     2581 ctggcggcca gtaaaggcat tgagctggtg tatgtgaata ccaaagggat gagcgatccg
     2641 gtacagaagc tgcgggcgct gacaggagat gtcgggttcg atgacatttt tgtttatgcg
     2701 gcggtgcctg ctgtcgttga gatggctgac gaattactgg cggaagatgg ctgcctgaac
     2761 ttctttgccg ggccgacgga taaaaacttc aaagtgccgt ttaatttcta caacgtccat
     2821 tacaacagca cgcacgtcgt cggtacatct ggcggttcaa cggacgacat gaaagaggcg
     2881 attgccctta gcgccacggg gcagttacag ccgtcgttta tggtgaccca tattggtggc
     2941 ctggatgcgg tgccagaaac cgtgctcaat ctgccggata tcccaggcgg taaaaaactc
     3001 atttataacg gcgtgaccat gccgctcact gccattgccg attttgccga aaaaggcaaa
     3061 accgatccgc tgtttaaaga gttggcgcgg ctggttgagg aaacgcacgg catctggaat
     3121 gagcaggccg agaaatatct gctggcgcaa tttggcgttg atatcgggga ggccgcgcaa
     3181 tgatgtccct ggcgtggcca ttatttcgcg ttacggaaca ggcagcgttg gctgcctggc
     3241 cgcaaaccgg atgtggcgac aaaaataaaa ttgatggcct ggcggtcacc gcgatgcgcc
     3301 aggcattaaa cgacgtcgct tttcgtggac gagtggttat cggcgaagga gaaattgacc
     3361 atgcgccgat gctgtggatt ggcgaagagg tgggcaaagg cgatgggcca gaagtcgata
     3421 tcgcggttga tccgattgaa ggcaccagga tggtggcgat ggggcagagc aatgcgctgg
     3481 cagtcatggc cttcgcccca cgaggcagcc tgctacacgc tcccgatatg tatatgaaaa
     3541 aactggttgt taatcggctg gcggcgggcg cgattgatct gtctttgcca ctggtggaca
     3601 acctgcgcaa cgtggcgaaa gcgttaggca aaccgctgga caagctgcgc atggttacgc
     3661 tggataaacc gcgcctgagt gccgcgattg aagaagcaac acagctgggc gtgaaggttt
     3721 tcgctctgcc ggatggcgat gtcgccgcca gcgtgctgac ctgctggcag gataatcctt
     3781 acgatgtgat gtacaccatc ggcggtgcgc cagaaggcgt gatttctgcc tgtgccgtta
     3841 aagcattagg cggggatatg caggcccagc tgattgactt ttgtcaggct aaaggggatt
     3901 acacggaaaa tcggcagatt gcagagcagg agcgcaagcg ttgcaaggca atgggcgttg
     3961 acgttaaccg tgtgtactcg ctcgatgaac tggtgagggg gaacgatatc ctctttagcg
     4021 ctacgggcgt gacgggtggc gagttggtga acggtatcca acagacggcg aatggggtgc
     4081 ggacgcagac attactgatc ggcggcgcgg accaaacgtg taatataata gactccctgc
     4141 attgatggtg atctatcgga agaccaatgg cgacgctgac agaagatgat gtgcttgagc
     4201 aactggacgc acaggacaat ttattttcat ttatgaaaac tgcgcattct attttgctcc
     4261 aggggatacg ccagtttctg ccgtcgctgt ttgtcgataa cgatgaagag atcgtcgaat
     4321 atgcagtgaa gccgttactc gcccaaagcg gcccgcttga cgatattgat gttgcgctgc
     4381 gtttgattta tgcgctgggg aaaatggata aatggctgta cgccgatatc acgcattttt
     4441 cccagttctg gcattacctg aacgaacagg atgaaacgcc cggatttgcc gatgacatga
     4501 cctgggattt tatcagcaac gtcaatagca taacccgcaa tgcgacgctc tatgacgcat
     4561 tgaaagcgat gaagttcgcc gatttcgccg tctggtcaga ggcgcgtttt agcgggatgg
     4621 tcaaaacggc gctgacgctg gcagtaacga ccaccttaaa ggaattaacg ccgtgaaaat
     4681 tgaattaacg gtgaatgggc tgaagataca ggcacagtac cagaacgaag agattgaaaa
     4741 tgtacataaa ccgttgctgc acatgttggc ggccttacag acggtaaatc cgcagcggcg
     4801 tacggtggtt tttctttgcg ctccgccggg gacgggtaaa tctaccctaa ccaccttctg
     4861 ggaatatatc gcgcaacaag acccggaact gcccgctatt cagacgctac cgatggatgg
     4921 ttttcaccat tacaatagct ggctggatgc gcatcaattg cgccccttca aaggcgcacc
     4981 agagacattt gacgttgcga aactggcgga aaatctgcgc caggtcgtgg aaggggattg
     5041 tacgtggccg cagtacgatc gacaaaagca tgatcctgtt gaagatgcgt tgcacgttac
     5101 cgcaccactc gtcatcgtcg aaggaaactg gctattactg gatgatgaaa agtggcagga
     5161 attggcatct ttctgcgatt tttctatttt tattcatgca cctgctcaaa ttctgcggga
     5221 gcgcttgatt agtcgtaaaa ttgcgggagg attatcgcgg caagaagccg aagcatttta
     5281 tgcccgaacc gatggcccca atgtcgagcg tgtgctgatg aatagtcgtc aggccaatct
     5341 gatagtagag atgactgaag aaggccggta ttacttcaca agctgacaat ttattccagt
     5401 tattgcaggg ttattattac gccagcctgg aataaagctt cccacaaaag gggataaaag
     5461 tgtgatgtga gtcagataaa tgtcttcttc ggctggacaa acattccttt tattccacgt
     5521 ttcgcttatc ctagctgaag cgtttcagtc gattaaatgt tcgacaatta accaatcagt
     5581 cgcagtttgc gacaggtaag gtttccccgg acgatttgct ggattactct gtctggcaaa
     5641 tttgctcagg gaaaaccttg caggagatct atgaccgtac gcgtagcgat aaatggcttc
     5701 ggtcgcatcg ggcgtaatgt ggttcgtgct ttgtatgaat ccggacgccg ggcggaaatt
     5761 accgtggtgg caatcaacga actggcggat gctgcgggca tggcgcattt gttgaaatat
     5821 gacaccagcc atggccgttt tgcatgggaa gtacgacagg aacgcaatca actttttgtt
     5881 ggtgatgacg ccatccgtgt attgcatgaa cgttcactgc aatcgctccc ctggcgtgaa
     5941 cttggcgttg atgtagtcct cgactgcacc ggcgtatatg gctcccgcga gcatggtgaa
     6001 gcacacattg ccgccggggc taaaaaagtg ctcttttcac atcctggcag taacgatctc
     6061 gacgcgaccg ttgtttacgg cgtcaatcag gatcaacttc gtgcggaaca ccgcatcgtt
     6121 tctaacgctt cctgtaccac gaattgcata attcccgtca tcaaattgtt agatgatgcg
     6181 tacggtattg agtccggcac tgtgaccaca attcactccg ccatgcacga tcaacaggtt
     6241 attgatgcat accatcctga cctgcgtcgc acccgggcag ccagccagtc gatcattccg
     6301 gtcgatacta aactggccgc cggtatcaca cgattttttc cgcaatttaa cgatcgcttt
     6361 gaagcgattg cggtacgtgt gccaaccata aatgtgacgg caatcgattt aagcgtgacg
     6421 gtgaagaaac ctgtaaaagc caatgaagtc aacctgttgc tgcaaaaagc agcacaaggt
     6481 gcatttcatg gtatagttga ctatacggaa ttgccgttgg tctctgtaga ttttaaccac
     6541 gatccgcaca gtgccattgt cgatggcact caaacccggg tcagtggcgc acacctgatc
     6601 aaaacgttgg tctggtgcga taacgaatgg ggctttgcta accgaatgct cgacacgacg
     6661 ttagctatgg ctactgttgc tttcaggtaa gacgcaagca gcgtctgcaa aacttttaga
     6721 atcaacgaga ggattcacca tgtctgtaat taagatgacc gatctggatc ttgctgggaa
     6781 acgtgtattt atccgtgcgg atctgaacgt accagtaaaa gacgggaaag taaccagcga
     6841 cgcgcgtatc cgtgcttctc tgccgaccat cgaactggcc ctgaaacaag gcgcaaaagt
     6901 gatggtaact tcccacctgg gtcgtcctac cgaaggcgag tacaacgaag aattctctct
     6961 gctgccggtt gttaactacc tgaaagacaa actgtctaac ccggttcgtc tggttaaaga
     7021 ttacctcgac ggcgttgacg ttgctgaagg tgaactggtt gttctggaaa acgttcgctt
     7081 caacaaaggc gagaagaaag acgacgaaac cctgtccaaa aaatacgctg cactgtgtga
     7141 cgtgttcgta atggacgcat tcggtactgc tcaccgcgcg caggcttcta ctcacggtat
     7201 cggtaaattc gctgacgttg cgtgcgcagg cccgctgctg gcagctgaac tggacgcgct
     7261 gggtaaagca ctgaaagaac ctgctcgccc gatggtggct atcgttggtg gttctaaagt
     7321 atctaccaaa ctgaccgttc tggactccct gtctaaaatc gctgaccagc tgattgttgg
     7381 tggtggtatc gctaacacct ttatcgcggc acaaggccac gatgtgggta aatccctgta
     7441 cgaagctgat ctggttgacg aagcaaaacg tctgctgacc acctgcaaca tcccggttcc
     7501 gtctgatgtt cgtgtagcaa ctgagttctc tgaaactgca ccggctaccc tgaaatctgt
     7561 taacgatgtg aaagctgacg agcagatcct ggatatcggt gatgcttccg ctcaggaact
     7621 ggctgaaatc ctgaagaatg cgaaaaccat tctgtggaac ggtccggttg gcgtgttcga
     7681 attcccgaac ttccgcaaag gtactgaaat cgtggctaac gctatcgcag acagcgaagc
     7741 gttctccatc gctggcggcg gcgacactct ggcagcaatc gacctgttcg gcattgctga
     7801 caaaatctcc tacatctcca ctggcggcgg cgcattcctc gaattcgtgg aaggtaaagt
     7861 actgcctgca gtagcgatgc tcgaagagcg cgctaagaag taaaaaatca cagggcaggg
     7921 aaacctgccc ttgttgcagc gcgcttttaa agcacgcact ttttcatact ctaaataatt
     7981 cgagttgcag gaaggcgaca agagagtgaa tcccatgagc ttacataagt aagtgactgg
     8041 ggtgagcgaa cgcagacgca gcacatgcaa cttgaagtat gacgagtata aggcccgacg
     8101 atacaggaca agagacatgt ctaagatttt tgatttcgta aaacctggcg taatcactgg
     8161 tgatgacgta cagaaagttt tccaggtagc aaaagaaaac aacttcgcac tgccagcagt
     8221 aaactgcgtc ggtactgact ccatcaacgc cgtgctggaa accgctgcta aagttaaagc
     8281 gccggttatc gttcagttct ccaacggtgg tgcttccttt atcgctggta aaggcgtgaa
     8341 atctgacgtt ccgcagggtg ctgctatcct gggcgcgatc tctggtgcgc atcacgttca
     8401 ccagatggct gaacattatg gtgttccggt tatcctgcac accgaccact gcgcgaagaa
     8461 actgctgccg tggatcgacg gtctgctgga cgctggtgaa aaacacttcg cagctaccgg
     8521 caagccgctg ttctcttctc acatgatcga cctgtctgaa gaatctctgc aagagaacat
     8581 cgaaatctgc tctaaatacc tggagcgcat gtccaaaatc ggcatgactc tggaaatcga
     8641 actgggttgc accggtggtg aagaagacgg cgtggacaac agccacatgg acgcttctgc
     8701 actgtacacc cagccggaag acgttgatta tgcgtatacc gagctgagca aaatcagccc
     8761 gcgtttcacc atcgcagcgt ccttcggtaa cgtacacggt gtttacaagc cgggtaacgt
     8821 ggttctgact ccgaccatcc tgcgtgattc tcaggaatat gtttctaaga aacacaacct
     8881 gccgcacaac agcctgaact tcgtattcca cggtggttcc ggttctactg ctcaggaaat
     8941 caaagactcc gtaagctacg gcgtagtgaa aatgaacatc gataccgata cccaatgggc
     9001 aacctgggaa ggcgttctga actactacaa agcgaacgaa gcttacctgc agggtcagct
     9061 gggtaacccg aaaggcgaag atcagccgaa caagaaatac tacgatccgc gcgtatggct
     9121 gcgtgccggt cagacttcga tgatcgctcg tctggaaaaa gcattccagg aactgaacgc
     9181 gatcgacgtt ctgtaagtca ttcctttctg cttatctcaa ggcccgctct gcgggtcttt
     9241 ttttcgccaa aagcaaggtg atacagatga gaaatctgtg atctatttgg caaaattatg
     9301 ctttattgtt tacccttgtc agactgcccg tcataaggcg gcggagtgta tttctccatt
     9361 ttgagtcagt tgaaaaggaa tattgaatgg aagatttgaa tgttgtcgat agcataaacg
     9421 gcgcgggaag ctggctggtg gctaaccagg cgctgctgct aagttatgca gtaaacatcg
     9481 tggcggcact cgcgatcatc atcgttggtt tgattatcgc gcggatgatt tccaacgcgg
     9541 tgaatcgcct gatgatctcc cgtaaaatcg atgccactgt tgctgatttt ctttctgcat
     9601 tagtccgtta cggaattatc gcctttacgc taatcgctgc actgggccgc gtgggtgtac
     9661 aaacagcgtc agtcattgct gtactcggtg ccgcaggctt agcggttggt ctggctttgc
     9721 aggggtcact gtctaacctg gccgctggcg tgttacttgt catgttccgc ccgttccgtg
     9781 ccggagaata tgttgacctc ggcggcgtag ccggtactgt gctgagtgtg cagattttct
     9841 ccaccaccat gcgtactgca gacggtaaaa ttatcgttat tccgaacggt aaaattattg
     9901 ccgggaatat tattaacttc tcccgcgagc cagctcgccg taacgaattt attattggcg
     9961 tggcgtatga ttccgatatc gatcaggtta agcagatcct gaccgatatt atccagtctg
    10021 aagatcgcat tttgaaagat cgcgaaatga ctgtgcgtct gaacgaactt ggtgcatcgt
    10081 cgattaattt cgtggtccga gtctggagca acagcggcga tctgcaaaac gtgtactggg
    10141 atgtgctgga gcgtattaaa cgtgaatttg atgccgccgg tatcagcttc ccgtacccgc
    10201 aaatggatgt gaactttaag cgggtgaaag aagacaaagc tgcgtaatca acgctgaggc
    10261 cagataatac tctctggcct ctctcttatt agtttttctg attgccaatt aatattatca
    10321 atttccgcta ataacaatcc cgcgatatag tctctgcatc agatacttaa ttcggaatat
    10381 ccaacgtgtt ttcttattac tttcaaggtc ttgcgcttgg ggcggctatg atcctaccgc
    10441 tcggtccaca aaatgctttt gtgatgaatc agggcattcg tcgtcagtac cacattatga
    10501 ttgccttact ttgcgctatc agcgatttgg tcctgatttg cgccgggatt tttggtggca
    10561 gtgcgttatt gatgcagtcg ccgtggttgc tggcgctggt cacctggggc ggcgtagcct
    10621 tcttgctgtg gtatggtttt ggcgctttta aaacagcaat gagcagtaat attgagttag
    10681 ccagtgccga agtcctgaag caaggcagat ggaaaattat cgccaccatg ttggcagtga
    10741 cctggctgaa tccgcatgtt tacctggata cttttgttgt actgggcagc cttggtgggc
    10801 agcttgacgt cgaaccaaaa cgttggtttg cgctcgggac aattagcgcc tctttcctgt
    10861 ggttctttgg tctggctatt ctcgcagcct ggctggcacc gcgcctgcgc acggcaaaat
    10921 cacaacgcat tatcaatctg gtagtgggat gtgttatgtg gtttattgcc ttgcagctgg
    10981 cgagagacgg tattgctcat gcacaagcct tgttcagtta ggcgctatct gatggaaaaa
    11041 taaaacagag gcgctaagct tgcctccaga ggtcctgaat tttgggcaag tcaattaaca
    11101 cggagagact aacgtgaagt tcaaagttat cgccctggcg gcattaatgg gtattagcgg
    11161 gatggcagcg caggctaacg aattgccgga tggaccgcat attgtcacct ccggtacggc
    11221 aagcgtggat gcggtgccag acattgccac tcttgcgatt gaagtcaacg tggccgcgaa
    11281 ggatgccgct actgccaaga aacaggcgga tgagcgcgtc gcacaataca tttccttcct
    11341 tgaactcaat cagatcgcga aaaaagatat cagctcagcg aacttacgca cccagccaga
    11401 ttatgattat caggatggta aaagtatcct gaaaggctac cgtgctgtga gaacggtgga
    11461 agtcacgctc cgtcagttag acaaactgaa ttccttgctg gatggcgcgc tgaaggcggg
    11521 tcttaacgaa attcgttctg tgtcgctggg cgtggcgcag ccggatgcct ataaagacaa
    11581 agcgcgtaag gcagcgattg ataacgcgat tcatcaggcg caggaactgg cgaacggctt
    11641 tcatcgtaaa ctggggccgg tatatagcgt gcgctaccat gtttccaact atcagcccag
    11701 cccaatggtg cggatgatga aagccgatgc cgcgccggtg tccgcccagg aaacttacga
    11761 gcaggccgct attcagtttg atgatcaggt cgatgtggtc ttccagttag aacctgtgga
    11821 tcaacaaccc gctaaaacac ctgcagcaca ataatatttg tagcccgacg tattcgtcgg
    11881 gctaatgcct ttacccgata ttgcctcctt tttctgtaat tttctgtaaa accatgacgt
    11941 aatcacctat ctttgctcgc ggtttcatca aggataggct gactgaaacg gttaagcgga
    12001 caaggatgcg ggggaggggg tatggacatt tttatttcga aaaagatgcg caatttcatt
    12061 ttattagcgc aaaccaataa tattgcccgg gcggcagaaa aaatccatat gacggcttcg
    12121 ccatttggta aaagcattgc cgcgctggaa gaacaaattg gctatacgct atttacccgc
    12181 aaagataata atatcagcct caataaagcc ggacaggaac tgtatcaaaa actgttcccg
    12241 gtttatcaac gactttctgc gattgataat gaaatccata actcagggcg tcgttcacga
    12301 gaaattgtga ttggcataga taatacttat ccgacaatta ttttcgatca gttgattagt
    12361 ctcggagata agtatgaagg cgtgaccgcc cagccagttg agttcagcga aaacggcgtt
    12421 atcgataatc tttttgaccg tcagttagat tttattatct ccccacagca tgtatctgca
    12481 cgagttcagg aactggaaaa cctgactatc agtgaactac caccgctgcg attgggcttt
    12541 ctcgtttctc gccgttatga agagcgacaa gagcaagagc tgcttcagga gctaccctgg
    12601 ctgcaaatgc gctttcagaa ccgggctaac ttcgaagcaa tgattgatgc gaatatgcga
    12661 ccttgtggga tcaatcccac cattatttat cgtccctaca gttttatggc caaaatcagc
    12721 gccgtggagc gcggacattt tctgacggtg atcccgcatt ttgcctggcg actggtgaat
    12781 ccggcaacgc tgaaatattt tgatgcgccg cacaggccga tgtatatgca ggaatatctt
    12841 tattcaatca gaaatcatcg ttataccgcc acgatgcttc agcatattgc tgaagatcgt
    12901 gacgggacaa accattaacc cagcatcgag ccggttgcaa ttaaattacg gtgtaagtcg
    12961 aagacgtggc taagatcgtg gtgaatatgt ccgccgggcg cattttccag ataacgatgc
    13021 agataatccc gatacatagg atgtgcacaa ttatcaatga tagtgcgggc gcgttgaagc
    13081 ggggaaagac cgcgcagatc ggcgatccct tgttcggtga tgatcacttt gacgctgtgt
    13141 tcgctgtgat caacatggct gcacattggc acgacggttg agatcttgcc ttctttagca
    13201 atcgacggag ccataaagat cgacagatac gcgttgcgtt caaaatcacc gctgccgccg
    13261 atgccgttca tcagatcgac cccggctacg tgcgttgagt tggcatgccc gtaaatatca
    13321 aactccaggc cgacgttcag agcgatgacg cccagacgac ggatgatttc cgggttattg
    13381 gaaatctcct gcggacgcaa cacaatgcgg ctggcaaagt aatccatatt gtcgtaaatc
    13441 ttgcgcaggg aatcggccga gattgtcagg ctggaggcgc tggccccgct gattttgccg
    13501 gtttccagta aatgcaccac cgattcctgt agcacttccg aatacatcat aaacggagga
    13561 atttccgggt tttcccccag acgcgccatt accgcattat tgatattgcc cacgccactt
    13621 tgcagcggca gaaattccgg cggaatacgc ccatgcgcca tttcctgcaa caagaacgtg
    13681 accacgttat cggcaatctg ctggcacatg ggattttgct tatccagcat attaccggcg
    13741 tcaggcaagt tggtttccac gacggcgaca atctttttcg gatcgatttg cacatagcgg
    13801 gtaccgacgc gatccattgc atggaagatc gacacgctat tgcgccgcgg tggcgcgcca
    13861 ggaatcacaa tatctgccag ttctgcaacg cgcggatcgt gatagtgatt aagttcaatg
    13921 atcactttct tcgctcgcag cagccaggtc ggcgcattac cgatcccgct ggttaaccag
    13981 actcgaccat ccggtgccag tgccgatgct tcgatgacgg caacatcaat gtcgccgaag
    14041 aaaccgtaat tgaccatttg cgccacttcg ctcaaatgca ggtcaacgaa actcaccgcg
    14101 ccctgattga tctttttacg taaaccggac gatgtttgat atggcgcacg ccaggaaaca
    14161 gcatcggcgt cagaaagtac atcgtcagcg gtggcgctga ttgacgcccc cgtcagcagg
    14221 cgaatttgat acggcttttt ggcctcatgc tgttcgttag ctctgcgggc aatcgcggtg
    14281 ggtaaggctt tcggcgaacc cgctggggta aagccgctaa atgccaccat gtcgttatgc
    14341 tggataattt ctgccgcttc atcggcggtc atccttgtcc actgagtttc cattttaact
    14401 ccttcgttcg cagggattaa tgaccaacga aattaggttt acgtttttcg aggaaagcgt
    14461 tcatcccttc ctggtagtct tcgctgtcat aaaccgcgcg gcgcatcccc tgaatacgtt
    14521 caaattcatc ggagttcatg gtgtgcgctt cgcccagtac acgcagctct tctttgataa
    14581 cggcaatggc taacggcgct ttctcagaga tgtggtgcgc catttgtaag gtgaaatctt
    14641 ccagttcttc cacttccaca acatggttga ggatgccgac agccagcgcg cgctgggcgg
    14701 tgattggcga agcggtaaaa atcagctctt tgacaatgtg gaagcccgcg tcgcgggtca
    14761 gattgtgaat gccgaccagg ttatacggga caccgaggtt tacaggtgtc attgagaagg
    14821 ttgaggtact ggcggcgata atcagatcgg aactcatgat catttcaaat gcgccacccc
    14881 aaacactacc ttccaccatc gaaatgatcg gtttcgggaa tttttggatc atgcgggtga
    14941 tttgacgcaa cggatcatca taggagagcg gatcgcgacc gccagacggc agttcgtgaa
    15001 tatcgtgacc tgcggagaag actttggatc cactcggcgc gcgcaaaatg atacagcgaa
    15061 tttccggccg gttgagatcg cttaatgcct gcataagatc atcaataaag actttactta
    15121 aggcattaag ttttcggcca tagttaaact caatgaccgc cactttgttg atagtgacaa
    15181 cgttcacata ctgataagac ataaaaattc ctttaatcaa aatattgcgt ctggataaat
    15241 tcactgagct gtcgcaggcc ggtgcgcggt gagagcgtat tgtttttgac cgctaaaagc
    15301 gtctggcggt aatagcgatc gaaatcttca ttcgcgaaca ggtgattcag tacttcttct
    15361 tcggtttgtt tacgcagcca ttccactgat tgttgttgcc gtacttgttg caaacgacca
    15421 ctggcagtta gcgcggtttt gaagtcgatg atggcgtgcc agatctcatt gattccacgt
    15481 ttttccagtg cgctacaagt cagaacccgt ggctgccatt cgtcgtattt gtgtcgcaga
    15541 atatgcaggg cactctcgta catatgctgg gcaatggcga cattggtatg gttatcgcca
    15601 tcgtctttgt tgataacgat cagatctgcc acttccatca gccccttttt aatgccctgc
    15661 agatcatcgc cgccaccggc aatttgcaac gagataaaac agtccaccat gcgggcgact
    15721 tccgtttccg actgtccgac gccaaccgtt tcgacaatca ctacgtcata acccgccgct
    15781 tcgcataaca gcattaattc ccgcgctcgc tgactggcac cgcccagatg accggaggag
    15841 ggtaccgggc gaataaacgc cgcctcggca cgcgccagat cattcatgcg ggttttatct
    15901 ccgagaatgc taccgccagt gaccgggctg ctgggatcga ccgcaataac cgcaaccttt
    15961 agtccctcac gaatcaacaa catgccaaag gcttcaagaa aggtactttt ccccgcgccg
    16021 ggtgtgccgg taacacccag tcgcagggcg ttaccacaga acggcataat ggcatcaagc
    16081 agttgcgtac ttagcgcctg atgacgcggg tgacggcttt ccaccagcgt catggcctgg
    16141 gcgagcgtgg cacgctcacc ctgacgtaag cggcgaatac tttctgccag cgtggcttca
    16201 ttaatcatga tgctggctta tcagattcag tacgtcgcgc acgctgtcga gcataggcgt
    16261 acctggacca taaatcgccg ccacgccgcg ctcctgcagg aaggcgtaat cctgcggcgg
    16321 aatgacgcca cccgcgacca cgcagatatc ttcgcgtccc cattttttca gcgcttcgac
    16381 cagttccggg atcagcgttt tatgaccggc agccagtgaa gatgcgccca ctacgtgaac
    16441 gtcgttttct actgccaggc gggcgatctc ttcaggtgta gagaacatcg ggcttaaatc
    16501 tacgtcgaaa ccgagatcgg aataggcgct ggcgatcact ttcgcgccgc gatcgtgccc
    16561 atcctggccc attttggcga tcagaatgcg cgggcgacga ccattgtcgg caaggaactg
    16621 ctccgtttgc gcaacaatgg catcgaactc ggtggccgat ttctcagact gatgatagct
    16681 ttgcgcaatc acgccggtaa cacactggct tggcaccaga taacggtcaa atgccgcttc
    16741 cagtgcatcg gaaatttcac caagcgttgc gcgaacgcga gcggcattaa cagcggcagc
    16801 cagcaggttt tcgttatgct gtgcggcgtg agtcagggcg ttcaacgcgg cggttacggc
    16861 ggcatcatca cgggtggcgc gaatgcgttc cagcgaagca atttgctcgt tacgcaccat
    16921 cacgttgtcg atctcaagta catcggtttc gtcttcgtga tccagtttgt acttgttgac
    16981 accaacgatg acacgcttgc cctggtcgat caacgactgt tcgcgcgctg aggcctcttc
    17041 gatcattcgt tttggcagac ctgcttcgat cgctttcgcc atgccaccgg cttcgtcgat
    17101 ctgttggata atggctctgg cttgtttgac gatttgatcg gtcagcgatt caacgtaata
    17161 ggatccggcc agtggatcga cggtgcggca gagttctgat tcttcctgaa tgatgatctg
    17221 ggtattgcgg gcaatgcgtg ctgagaaatc ggtaggcaaa ccaagcgctt catcaaaggc
    17281 gttggtatgc agtgactgag taccgcccag cgttgcagcc agtgcttcaa tggtggtgcg
    17341 tataacgttg ttatacggat cctgttcagt caggctccag cctgaggtct ggcagtgggt
    17401 acgcagcgcc agtgatttcg gatcctgtgc gccaaatcca ctgaccgctt cgctccataa
    17461 ataacgtgcc gcacgcaaca tggcgacgtt cataaacaga tccatgccaa tgccgaagaa
    17521 gaacgacagg cgaggagcga agtcatcaat tttcagcccg gcggagattg ctgctttgat
    17581 gtactcaatc ccatcagcga gcgtaaatgc tacctgctgc acgcagttgg cacccgcttc
    17641 acccatatgg taaccgctga tactgatggt attaaatcgc ggcatgttgc cggaacacca
    17701 ggcgatgatg tctgcgataa tacgcattga cggttttggc gggtaaatat aggtgttgcg
    17761 gcaaagatac tctttgagga tatcgttttg aatggtgccg gtcagtttat cgggtgtaac
    17821 accttgctct tctgcggcga caatataaaa cgccagtact ggtagtactg cgccattcat
    17881 ggtcatcgaa accgacattt tatccagcgg gatctggtcg aacaggactt tcatatcttc
    17941 cacggtgtcg atagcaacgc ccgctttgcc gacgtcgccc gccacgcgcg ggttatcgga
    18001 gtcgtagcct cggtgggtgg caaggtcaaa cgcaacggaa agaccttttt gcccggcggc
    18061 caggttacgg cgataaaaag cgttggactc ttttgctgtt gaaaaaccag catactgacg
    18121 gatggtccac ggttgggcgg tatacatagt ggcacgcggg ccacgaacgt aggggggcaa
    18181 accaggaagg gtacctgtca cctccagatt atcgagatcg gcttcggtat acagcggctt
    18241 gatggcgatc ccttccgcgg tttgctgaac cagcgagtcg acagttttct cccgacggct
    18301 caattccttg ttggcaagct gttgccactc ctgcacgtta gacattattt gctccgtaaa
    18361 acgcaatcaa aatgagggta tttgcgctta cggtgagctt tttacgtggg tttgtcgcca
    18421 gcaaaaaaaa tgcattcaga cgtcgttttt tgccgcctga gatttgtcta ttttgtgatg
    18481 tgattcaagg aatacaaaaa gaagtgagga taacgcctga tatgtgctat caggcattat
    18541 ttgatggatt aatcctgacg aaggactttg tgaccataat cgagcaacgc atcagtgact
    18601 ttacgcatca tgcggctttc aggagcaaag cggtgccagt agagcatccg gcgttgaaat
    18661 agccccggcg ttaagtcaat cagttcgccg ctggccagtt ctttctcgat ttgcaggtgc
    18721 gggatcatac agcaggtggt gccctggcga gcaagttgta cgaacgcttc tgaagaatta
    18781 acgatatggc acggtacgct gcctgggggc agatcgaagt tttgctgcaa aaaggcctgg
    18841 tgcatatcgt caagatggtc aaaggcgacc acaggtgctt tcaataatgc cgaacgcgtt
    18901 acgccgttag ggaaatattt ttcggcaaac ggttttgagc tgacgaacag atagtcaagc
    18961 gcaccgagct tatcgacaag gcaactcggc agcgcctgat gttgaatact caccgcgccg
    19021 accacttcgc cgcggcgcag acgttcctga gtgcgggttt catcttctac ctgcaagttg
    19081 aggcggatag gcgaatcagc caacacagga gccagcgccg gaagcaacca cgtcgccaga
    19141 ctgtcggcgt tgaccgccag tgaaagcagc agcggagtcg aaccggtttg ttcatcgccc
    19201 agccactctt cttccagcaa ctccacctgg cgtagcagtg ccagcagttt ttgcccttgt
    19261 tctgtcgggc gcggcggtac ggtacgcacc aacagcggct gcccgaacat attttccagt
    19321 tgcttaatgc gctgtgagac ggctgattgt gtaatgcaca gcttttgtgc cgcgcgttca
    19381 aatcctcgtt cacgtatcac cgcatccagt gcctgtaatg ttctgtagtc cgggcgtttc
    19441 attgctgttg tctgctcctg gtaaatgctt tttcctgcac tatgacacaa ttttgcgttg
    19501 ggtacagagc atttaacgca tacaaaaacg gtcgtaatgg aagttttggc tggcaatccc
    19561 attttcatat aaccctttgc tgagcgcttt ggcaaaactc tgtgggccgc aaaaccagaa
    19621 atgggtgtca cctttatttg ctattttatc agtaagatag tgcgcctgta ggcgctcacc
    19681 tttatgcgca tcaagcagat gcagtgtgac cctggcctgg gcacaaagtg aggtcagttt
    19741 atcaacatac caggcatcct cgcttcggct gacgcaatac cagagatcca caggaacaga
    19801 ggacgcgcca tgatgtttac gatactcaag ctgggcgata aagggggtaa tgccgatgcc
    19861 tcctgctatc cagacctggt gggagcaagg gagagtaaaa tcaaactttc cccatggccc
    19921 ttcaacgaag gcggactggc cgatttttat cgaggatgca agggtagagg tataatcccc
    19981 taaatttttg atggcaaagc gcaacgtgtt cttctctttg gtgtatgaag cgatagtaaa
    20041 agggtgagat tctttactgt gtgcgaacgt taagaatgca aactgccccg gagaatagtc
    20101 gatggcatgt tccagttcca gggtgacttc ggtaatttgt cctggatggt taacaatgtt
    20161 tttaatggta gcctgatgct tgtttttact accgtttaat ttcagcagcg aaatgggtaa
    20221 tggtgccaac ttactgattt agtgtatgat ggtgtttttg aggtgctccc gtggcttcca
    20281 tctccatcag ttgtccctcc tgctcagcta ctgaaggcgt ggtgcgtaac ggtaaaagta
    20341 ctgccggaca tcagcgctat ctctgctctc actgccgtaa aacatggcaa ctgcagttca
    20401 cttacaccgc ttctcaaccc ggtacacacc agaaaatcat tgatatggcc atgaatggtg
    20461 ttggatgccg ggcaaccgcc cgcattatgg gcgttggcct caacacgatt ttacgtcact
    20521 taaaaaactc aggccgcagt cggtaacctc gcgcatacag ccgggcagtg atgtgattgt
    20581 ctgcgctgaa atggacgaac agtggggcta cgtcggtgct aaatcacgtc agcgctggct
    20641 gttttacgcg tatgacagga tacggaggac ggttgtggcg cacgtcttcg gtgaacgcac
    20701 tctggccaca ctggagcgtc ttctgagcct gctgtcggcc tttgaggtcg tggtatgg
//
LOCUS       DADXDL010000091        20456 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.091, whole genome shotgun sequence.
ACCESSION   DADXDL010000091 DADXDL010000000
VERSION     DADXDL010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20456
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.091"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            98..1795
                     /locus_tag="IRB70_003779"
     CDS             98..1795
                     /locus_tag="IRB70_003779"
                     /EC_number="4.2.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="urocanate hydratase"
                     /protein_id="HBC0633638.1"
                     /translation="MSKPSDPRIDTSRVIHAPHGTQLHCKNWQIEAAYRMLQNNLDPD
                     VAENPQHLVVYGGIGRAARNWECFDKILESLKNLEADESLLVQSGKPVGVFKTHTDAP
                     RVLIANSNLVPQWANWDHFNELDRKGLFMYGQMTAGSWIYIGSQGIVQGTFETFVEAG
                     RQHYNNSLSGKWILTAGLGGMGGAQPLAATLAGACSLNIECQQSSIDFRLRTRYVDKQ
                     AKDLDDALALIKYHTERKEAVSIALLGNAAEIVPELVKRAHQGSIKPDLVTDQTSAHD
                     LVYGYLPMGWSVEQWRAAQQDPQQHARLQKEAAQSCVAHVQGMLDFQAMGIPVVDYGN
                     NIRQVAFNEGLQNAFDFPGFVPAYIRPMFCEGKGPFRWVALSGDPEDIYKTDAKIKEL
                     FPNNVLTHRWLDMARERIAFQGLPSRICWLGLGERHLAGLAFNEMVRNGELKAPIVIG
                     RDHLDTGSVASPNRETESMLDGSDAVSDWPLLNGLLNTAGGATWVSLHHGGGVGMGYS
                     QHAGMVIVADGSEEAEKRLARVLVNDCASGVMRHADAGYEAAIECAKNYGLKLPMIR"
     gene            1959..3368
                     /locus_tag="IRB70_003780"
     CDS             1959..3368
                     /locus_tag="IRB70_003780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000446074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytosine permease"
                     /protein_id="HBC0633639.1"
                     /translation="MESSSPIRSKKPVLESNTINAVPESARHGSPSSQFTLWLSANLQ
                     ITAVVDGALAIIFGSEAMSAIIGLLIGNIIGGAVMALHSSQGAKLGLPQMISSRIRFG
                     VKGAALPLLMVIIMYLGFAATGTVLSGQAINRIFGFESASTGIIIFGMLTAMIALVGY
                     KLIHVVGRVAGILSILGFIYLATQLSGHYDVAAAFGQKPFSLSVFLLTIALSAGWQLT
                     FAPYASDYSRYLPSDTPAKSIFFATFLGTTLGAQCAMTFGVLVAACGANFLKDQVGFM
                     GELAGPTFAILIYMVIVCGKLTVNCLNAYGGFMSILATVSAFNNRSQVSQRVRAAYVV
                     GFVLLSMVVALAASADFLNNFKNFVLLLLTVFVPWSAINLIDYYFISQGKTGIPALYT
                     PEGRYGAYNKTALTCYGVGVLVQIPFLNQKLYQGPISVLMDGADISWIVGLLITAVIY
                     YPWAKRTTCVPAYTIYPES"
     gene            3370..3960
                     /locus_tag="IRB70_003781"
     CDS             3370..3960
                     /locus_tag="IRB70_003781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001489692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HutD family protein"
                     /protein_id="HBC0633640.1"
                     /translation="MEPMLISAMDKPLQPWRNGGGVTRQLLAWPDDENWLLRISMANV
                     SQDGPFSAWPGVVRGLAILDGEGVKLTFADSIINLQRHDPALIFPGEAMPDCKLLGGG
                     VRDLNVMAREGDTGMLRVQSAVDWLPPSLAQAGLFTLCEGEWISGKKRVFVAANMLLW
                     LVAPDGRPWRFVPRKKVSVGELAGWWLYYLRGEKSL"
     gene            3957..5168
                     /locus_tag="IRB70_003782"
     CDS             3957..5168
                     /locus_tag="IRB70_003782"
                     /EC_number="3.5.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001516000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="imidazolonepropionase"
                     /protein_id="HBC0633641.1"
                     /translation="MSALTLWRNTTLATLSANDWGVIEKGALISRGDTIVWLGKATQI
                     PRELTADITEEHDLQGKLLTPGLVDCHTHLVYGGQRANEFEMRLQGVAYEDIARAGGG
                     ILSTVNATRAASETQLFELAVQRLQNWLREGVSTLEIKSGYGLTLEDEARCLRVIRRL
                     QQSTGLHIQSTFLGAHSLPPEFAGRSDDYITALCDWMCVLHEQGLIDAVDAFCENIAF
                     TPEQVRRVFSKAQSYGLPVKLHAEQLSDQQGAALAAAFSALSCDHLEYLSESGIAAMK
                     AAGTVAVLLPGAYYFLRETHLPPIVALRAAGVPIAISTDHNPGTSPNMSLPLMINMAC
                     TLFRMTPLEAVQGVTRNAAKALGLIDRGELAPGLRADMAVWDLNHPRELAYWFGHQPC
                     QGLIVGGKRSW"
     gene            5168..6118
                     /gene="hutG"
                     /locus_tag="IRB70_003783"
     CDS             5168..6118
                     /gene="hutG"
                     /locus_tag="IRB70_003783"
                     /EC_number="3.5.3.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000814583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formimidoylglutamase"
                     /protein_id="HBC0633642.1"
                     /translation="MKQTFLPWSGRVDSQETGISTRWHQHVQPFSEQSHGGCTLIGFA
                     VDDGVQRNGGRAGAAGGPGALRSMLGNMPVLCEGAIFDMGDVQSEDHALESAQNRLAA
                     NVSTAIARGSLPVVLGGGHEVAWGTFQGIMQSRPDIQRLLIVNLDAHFDLRMAEQANS
                     GTPFRQMQEWNAQYGKPFHYRVLGISRFANTQALFDRADCLGVRYWLDESLQFERGLH
                     EIANALSADIQACDAIYLTICLDVLPGYQAPGVSAPSPLGVPLNITEAIVNLIAGSEK
                     LIAADIAELNPDLDRDNLTAKVAARLAATIVRRGKTDRTN"
     gene            6169..7839
                     /locus_tag="IRB70_003784"
     CDS             6169..7839
                     /locus_tag="IRB70_003784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid lyase"
                     /protein_id="HBC0633643.1"
                     /translation="MKGLIRRVTVTVVLWSVCSIAMAKSTITLDGEHLSIDQAWSIAL
                     GDNDVKIAPKALGRMEKSYDLVMTAAHSGTPVYGLTVGVGLNKDQPIFDAKGNLTPEV
                     IDASKKFNAAALRAHSAGVGPMLPDYLARLSMVLRLNTMLHGQTGAQPYIAELYAEFI
                     NRGVTPLIPARGSIGAADIMLASHVGLVMMGEWKARVNGVEMSGGDALVKVGLKPLVP
                     QGKDMLAILSNNSVGTAYAIEAVRSARQVLNVSPVVFAMSLEALNGNVAPVLPQSIAV
                     RPFPQLADSAKEIRDALSGSYLWHKHDKRALQDPLSFRTTVYTISEAMRALRDAEDTI
                     TVQINSSDDNPATVLNADKAYQDSSQVAQYFVKDGAISGGIFPTANFESLPVALATQR
                     LTVALVHVSHNSMRRSLHLEDEHFTGLTRFLSAPGNKGHGFGSLHIPFVALHAENVDL
                     ANPVSFDIQPVAGGIEDTGANNDHAARRLKQVVDNLNVIYGIELMHSAQALDLRLQAD
                     PQLALGKSTKAMFTEYRKVVPFVDQDRVFTPDIAASQKFLEGYAINQK"
     gene            8110..9015
                     /locus_tag="IRB70_003785"
     CDS             8110..9015
                     /locus_tag="IRB70_003785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0633644.1"
                     /translation="MRGKIPKTELLVTFEVVARHESYTRAAEELALTQSAVFRQVSAL
                     EEFLRTPLFSHSKKRIFLNDAGKYYLGIVKETLNKLERDTNTIMTWQPTVQVIELAVN
                     PTFSTHWLIPNLHEFTKLHPDIIVNIHSLANNGDFLNREYDAVIMRENFCAPWAEVEY
                     LFEEEILPVCSGSLLAMSDQKLSVAELLTELPLLHQSTRITGWEEWFALSGVSSPLVN
                     NGPRFDLLSMLIAAVRSNLGVALLPRFAIQHDLDSGDMVIPCDVPIRTGNRFIMTWQE
                     EKSDSPHLQQFREWLLAKSVVPQEM"
     gene            complement(9049..9651)
                     /gene="cobO"
                     /locus_tag="IRB70_003786"
                     /pseudo
     CDS             complement(9049..9651)
                     /gene="cobO"
                     /locus_tag="IRB70_003786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308783.3"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
     gene            complement(9661..11313)
                     /locus_tag="IRB70_003787"
     CDS             complement(9661..11313)
                     /locus_tag="IRB70_003787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000042471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fumarate hydratase"
                     /protein_id="HBC0633645.1"
                     /translation="MSKPFIWQEPFLQNKDGTEYTLISDQHITVTELDGEEVIKIAPE
                     ALTLLARQAFYEASFFLRSAHLQQVASILNDPQASSNDKYVALQLLRNAEVSAKGVLP
                     NCQDTGTATIVASKGQQIWTGGNDAEALSKGIYTTFQENNLRFSQNAPLDMYTEVNTQ
                     TNLPAQIDISAVAGDEYHFLCINKGGGSANKAALYQETKSLLQPEKLTAFLIEKMKSL
                     GTAACPPYHIAFVVGGLSADQTLKVAKLASTKYYDNLPTSGNEQGQAFRDIELEKVLL
                     EASQQFGIGAQFGGKYFAHDIRVIRLPRHGGSCPIAMALSCSADRNIKAKINKHGIWL
                     EKLEHNPGQYIPASLREENHAQHVQLDLNRPLRDVMQDLARLPVGTRVSLSGPIVVAR
                     DIAHAKIKARLDSGEPMPDYLKHHIVYYAGPAKTPENMACGSLGPTTGGRMDGYVDTF
                     QAAGGSLVMLSKGNRSQQVTDACHKHGGFNLGSIGGAAALLAQEYVKSLRCLEYPELG
                     MEAVWMMEVENLPAFILVDDKGNNFFSQFEQQHRCASCPAGH"
     gene            complement(11421..12701)
                     /locus_tag="IRB70_003788"
     CDS             complement(11421..12701)
                     /locus_tag="IRB70_003788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308785.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate/amino acid:cation symporter"
                     /protein_id="HBC0633646.1"
                     /translation="MKKISLTTMILLALVLGMIIGVVLNNTASPETAKLYAQEISIFT
                     TIFLRLIKMIIAPLVVSTLVVGIAKMGDAKALGRIFSKTLFLFICASLLSIALGLITV
                     NFFMPGTGINFVAHGAETTGVVASEPFTLKVFISHAFPTSIVDAMAHNEILQIVVFSI
                     FLGCSLTAIGEKGSAIVHALDSLAHAMLKLTGYVMLFAPLTVFAAISALIAERGLAVM
                     VSAGIFMGEFYFTMLLLWVLLIGLAIVYVGPCIRRLTRALSEPALLAFTTSSSEAAFP
                     GTLEKLEQFGVSPKIASFVLPIGYSFNLVGSMAYCSFATVFIAQACNIHLSIGEQITM
                     LLILMLTSKGMAGVPRASMVVIAATLNQFNIPEAGLILLMGVDPFLDMGRSATNVMSN
                     AMGAAMVSRWEGEHFGEGCRGKALKPNESNVALP"
     gene            complement(12862..13179)
                     /locus_tag="IRB70_003789"
     CDS             complement(12862..13179)
                     /locus_tag="IRB70_003789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4387 domain-containing protein"
                     /protein_id="HBC0633647.1"
                     /translation="MKQSIVSLAQVIRSKNAGPYELVLDILFKTKENYERVKSSGQLT
                     PELIARLYHVEPDFIHRIVWFDPSNAVKIVMPRDIISGNVGDNDVYGAQQHAPLLNMS
                     FDL"
     gene            complement(13176..14546)
                     /locus_tag="IRB70_003790"
     CDS             complement(13176..14546)
                     /locus_tag="IRB70_003790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyclic terpene utilization AtuA family protein"
                     /protein_id="HBC0633648.1"
                     /translation="MARSFKVLSPTAILGYGFPEESFRKAMAESPDLIAVDAGSSDPG
                     PHYLGAGKPFTDRAGVKRDLRYMITAGVQNNIPVVIGTAGGSGAAPHLEWCREIIHEI
                     AREEQLAFSMALIPADVDKAIVHQVLDNGKITALDFVPPLTHDAIDESTYIVAQMGIE
                     PFQRALKEGAQVVLGGRAYDPACFAALPIMQGFDEGLALHCGKILECAAIAATPGSGS
                     DCAMGIIDDNGFTLKTFNPKRKFTETSAAAHTLYEKSDPYFLPGPGGVLNLKGCTFKA
                     VNDGEVYVSGSKHEETPYALKLEGARRVGFRCLTIAGTRDPIMIAGIDKIIDEVKTSV
                     SRNLSLDDDSIRINFHLYGKNGVMGDHEPMQTAGHELGIVLDVVAPTQEIANSVCSLV
                     RSTMLHYGYENRIATAGNLAFPFSPSDIQGGPVYEFSIYHLIEANDALRFDFHIEQVT
                     PEGVQA"
     gene            complement(14550..15791)
                     /locus_tag="IRB70_003791"
     CDS             complement(14550..15791)
                     /locus_tag="IRB70_003791"
                     /EC_number="4.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylaspartate ammonia-lyase"
                     /protein_id="HBC0633649.1"
                     /translation="MKIKQALFTAGYSSFYFDDQQAIKNGAGHDGFFYTGEPVTQGFN
                     AVRQAGECVSVQLILENGAVAVGDCAAVQYSGAGGRDPLFLAEHFIPFLNDHIKPLLV
                     GRDVDAFLPNARFFDKLRIDGNLLHTAVRYGLSQALLDATALATGRLKTEVVYDEWQL
                     PRVAESIPLFGQSGDDRYIAVDKMILKGIDVLPHALINNVEEKLGFKGEKLREYVRWL
                     SDRILSKRTSARYHPTLHIDVYGTIGLIFDMDPLRCAQYIASLEKEAQGLPLYIEGPV
                     DAGNKPDQIRLLTAITKELTRLGSGVKIVADEWCNTYQDIVDFTDAASCHMVQIKTPD
                     LGSIHNIVDAVLYCNSHSMEAYQGGTCNETDVSARTCVHVALAARPMRMLVKPGMGFD
                     EGLDIVFNEMNRTIALLQAKD"
     gene            complement(15791..17236)
                     /locus_tag="IRB70_003792"
     CDS             complement(15791..17236)
                     /locus_tag="IRB70_003792"
                     /EC_number="5.4.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylaspartate mutase subunit E"
                     /protein_id="HBC0633650.1"
                     /translation="MELRNKKLTHDEFMTERQQVLKTWETGKDVENFEDGVKYQQTIP
                     EHKRFSLALLKADKEGKTLSQPRAGVALMDEHIELLKTLQEECDLLPSTIDAYTRLNR
                     YEEAAVGIKKSIEAGTSKLNGLPVVNHGVAACRRLTETLQKPLQIRHGTPDARLLAEI
                     SMASGFTSYEGGGISYNIPYAKRVTLEKSIRDWQYCDRLMGMYEEHGIRINREPFGPL
                     TGTLIPPFISHSIAIIEGLLALEQGVKSITVGYGQVGSLTQDVAAIQSLRELAHEYFQ
                     SYGYTDYELSTVFHQWMGGFPEDESKAFAIISWGAAVAGMSGATKVITKSPHEAWGIP
                     TAAANIQGLKASRQMLNMVNEQKFPPCPAVELEIELIKSEVRAVLNKVFELGNGDIAR
                     GTVLAFESGVLDVPFAPAACNAGKILPVRDNTGAIRVLEAGAVPLPKDILDLRHDYVA
                     ERARFEGRQPTFQMVVDDINAVSHSKLIGRP"
     gene            complement(17255..18643)
                     /locus_tag="IRB70_003793"
     CDS             complement(17255..18643)
                     /locus_tag="IRB70_003793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate mutase L"
                     /protein_id="HBC0633651.1"
                     /translation="MQIVSVDIGSTWTKAALFAREGDALTLVNHVLTPTTTHHLAKGF
                     FSSLNLVLNVDNALPLFNNGEVALKYSSSAKGGLAVAAMGLVPSITLETAKVTAHSAG
                     AKIAQYYSYKLNRRDIQALEETQPDILLFTGGTDGGEESYGLNNARVLAESKLDCAII
                     YAGNRDIQDEVQEILGHKDLTIVDNVLPDLDHPNPLAARQAICDIFLKRIIKGKGLDV
                     VVDKTGEEPMPTPWTVFELVKAISNVDHSWKEFMLIDMGGATTDVYSACANTLSPDTV
                     LHGVPEPFVKRTVEGDLGMRVSAMVVGESAKELVNVNFAQQPAQLDAFYHYLRHLVAH
                     PDYLPANAEEKYFDTVLAGLCVGYATERHAGTKKEVCTCVGNVDLQMGRDLTTVRKVV
                     GSGGWLSRASQFDMHHWLKYRELNDDGKRILLPTEFEYYRDSRGLLPLLANVARVDPL
                     AAARTSIQCLTL"
     gene            complement(18643..19092)
                     /locus_tag="IRB70_003794"
     CDS             complement(18643..19092)
                     /locus_tag="IRB70_003794"
                     /EC_number="5.4.99.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylaspartate mutase subunit S"
                     /protein_id="HBC0633652.1"
                     /translation="MKKATLVIGVIGADCHAVGNKVLDRVFSNHGFRVINLGVMVSQD
                     EYIDAAIETGADAIVVSSIYGHGDIDCLGMRERCIERGLGDILLYVGGNLVVGKHDFA
                     DVETKFKEMGFDRVFAPSHDLEDVCQLMAHDINQRHDVDTRILEEAI"
     gene            complement(19639..20061)
                     /locus_tag="IRB70_003795"
     CDS             complement(19639..20061)
                     /locus_tag="IRB70_003795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633653.1"
                     /translation="MIPSQISFNTLPVNATYASETTVDTQKFSDILYSAGCSLKDLAY
                     LSRCLASIHPTIAKNIYETENLSDQKLLHIDCRSTNEIKINIFFGQQREGLIEINSDT
                     VIFSMLSSLIDSAISKFQHQIPVNGSVNRELLYEDYTD"
     gene            complement(20142..>20456)
                     /locus_tag="IRB70_003796"
     CDS             complement(20142..>20456)
                     /locus_tag="IRB70_003796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633654.1"
                     /translation="FNILTSDEYMSIMTPLMKCERSIHDHNRYVTGKDTLLLDYPPSG
                     NQIYFHIFPDESATLVLYFSNNDIECFVFERDIPSQYRFFKMFTNLALVIDQLTDANQ
                     IL"
BASE COUNT         4889 a         4855 c         5305 g         5407 t
ORIGIN      
        1 gataaacggg aattatagaa accgtttcta tattcattcg ttcgtttttt ctgaccgatt
       61 acagcgttta attttatcaa gtaacaggag aagattcatg agtaagcctt cagacccgcg
      121 tattgatacc agccgtgtaa tccatgcgcc acacggtacg cagctgcact gcaaaaactg
      181 gcaaattgaa gcagcctacc ggatgttgca gaacaacctt gatcccgacg ttgccgaaaa
      241 tccacagcat ctggtggtgt atggtggtat tggtcgtgcg gcacgtaact gggagtgttt
      301 tgacaaaatc cttgaatcac tgaaaaatct ggaagctgat gagtcactgc tggttcagtc
      361 cggtaaaccc gtaggcgtgt ttaaaacgca taccgatgcg ccgcgcgtat tgattgccaa
      421 ctctaacctg gtaccgcaat gggccaactg ggatcatttc aatgaactgg atcgtaaagg
      481 tctgttcatg tacggccaga tgaccgctgg ctcgtggatc tacatcggta gtcagggcat
      541 tgtgcaggga acgttcgaaa cctttgttga agcgggtcgt cagcactaca acaattcgct
      601 gagtggaaaa tggatcctga ccgcggggct cggtggtatg gggggcgcac aaccgctggc
      661 ggcgactctg gcgggggcgt gctcattaaa tatcgagtgc cagcaaagta gcatcgactt
      721 ccgtctgcgt acccgttatg tcgataaaca agcgaaagat cttgatgatg cactggcgct
      781 gattaaatac cacaccgaac gcaaagaagc cgtttctatc gcgctgctgg gcaatgcggc
      841 ggaaattgtt cctgagctgg tgaaacgtgc gcatcaggga tcgatcaaac cggatctggt
      901 gaccgaccag acctccgctc acgatctggt ctatggttac ctgccaatgg gctggagcgt
      961 agaacaatgg cgtgctgcac agcaggatcc acaacagcac gccagactgc aaaaagaagc
     1021 ggcgcagagt tgcgtggcgc atgttcaggg gatgctggac ttccaggcga tggggatccc
     1081 ggttgtcgat tatggcaaca acatccgcca ggtggccttc aacgaaggtc tgcaaaatgc
     1141 ctttgatttc ccgggctttg ttccggctta tattcgtcca atgttttgtg aaggcaaagg
     1201 tccattccgt tgggtggcgc tgtctggcga cccggaagat atctataaaa ctgatgccaa
     1261 aattaaagag ttgttcccca ataacgtact gacgcatcgc tggctggata tggcgcgcga
     1321 gcgcattgcc ttccagggac ttccttcacg tatttgctgg ctggggcttg gtgagcgtca
     1381 cctggcgggg ctggcattca acgaaatggt gcgcaacggt gaactaaaag caccgattgt
     1441 gattgggcgc gatcatcttg ataccggttc tgtcgccagc ccgaaccgcg aaaccgaaag
     1501 catgcttgat ggcagtgatg cggtttctga ctggccgttg ctcaacggtt tgctcaacac
     1561 tgcaggggga gcaacgtggg tatccctgca tcatggcggc ggcgtcggga tggggtattc
     1621 acaacacgcc gggatggtta ttgttgccga tggtagcgaa gaagccgaaa aacgtctggc
     1681 gcgtgtgctg gtgaatgact gtgcgtccgg ggttatgcgt catgcggatg cgggttatga
     1741 agcggcaatt gaatgtgcca aaaactatgg tctgaaatta ccgatgattc gctaaatatt
     1801 aacgccgtca tttaatattt gcgctaatac aggcggagaa taattcgcct gtataacaat
     1861 aattatcaaa aaatattttt acatcgtcga gagaaatatc tcccgaccct ctattgctgt
     1921 ttcaaaaaat gacctctcat tttgcaggag actttttcat ggaatcaagc agccctatcc
     1981 gcagtaaaaa gccagtatta gaatcaaata cgattaacgc cgttcctgag tctgctcgcc
     2041 acggctcgcc atccagtcag tttactttat ggctaagtgc taacttacaa attaccgctg
     2101 tggtggacgg cgcgttagcg attatttttg gctccgaagc catgtcagca ataattggtt
     2161 tattaatcgg taatattatt ggtggtgcag taatggcatt gcactcgtcg cagggggcaa
     2221 agctgggatt accccagatg atctccagtc gtatccgctt tggcgttaaa ggagcggcgc
     2281 taccgttact gatggtgatt attatgtacc ttggatttgc cgcgacgggt acagtattat
     2341 ccggtcaggc gattaaccgg atatttggtt tcgaatcggc atcgaccgga attattattt
     2401 tcggcatgct gaccgcgatg atcgcattgg tcggttataa acttattcac gtcgttggcc
     2461 gtgttgcagg gatattaagt attctggggt ttatttacct ggccactcaa cttagcggtc
     2521 actacgatgt ggctgcggca tttggtcaaa agccatttag tctgtcggtc tttttattaa
     2581 cgattgctct ctctgccgga tggcaattaa cgtttgcccc ttacgcctct gattattccc
     2641 gctatttacc ctctgatacg ccagcaaaat caatcttctt tgccaccttt ctgggaacca
     2701 cgcttggtgc gcaatgtgcc atgacgtttg gcgtacttgt tgcggcctgt ggtgctaact
     2761 tcctgaagga tcaggttggt tttatgggtg agttagccgg acccaccttc gctattctga
     2821 tttatatggt gattgtttgc ggcaaactga cggtgaactg tttgaatgcc tacggtggct
     2881 ttatgtcgat tctggcgacc gtcagcgcct ttaataatcg cagtcaggtt tcacagcgtg
     2941 ttcgtgctgc ctacgttgta gggttcgtgc tgttgtcgat ggtcgtcgcg ctggcggcaa
     3001 gcgcagattt tttgaataat ttcaaaaact tcgttctgct gctgttgacg gtatttgtgc
     3061 cgtggagcgc cattaatctc atcgactact acttcatctc acaaggtaaa accggtattc
     3121 cggcacttta taccccggaa gggcgttatg gcgcgtataa caaaaccgct ttgacgtgct
     3181 atggcgtagg cgtgttggtg cagatcccct tcctgaatca aaaactgtat cagggaccca
     3241 tttctgtcct gatggatggg gcggatatct cctggattgt cggcttgtta attaccgccg
     3301 ttatctatta cccgtgggcc aaacgcacca cctgcgttcc tgcttatacg atttatcccg
     3361 agtcttaata tggaaccgat gctgatttct gcaatggata agccgctgca accgtggcgc
     3421 aacggcgggg gggttacccg acagctgctt gcctggcccg atgatgaaaa ctggttgttg
     3481 cgcatcagta tggcgaatgt cagtcaggat ggcccttttt cagcgtggcc tggcgtggtt
     3541 cgtggcctcg cgatcctcga cggggaaggg gtgaagctaa cgtttgccga ttcgatcatc
     3601 aacctgcaac gtcacgatcc cgccttaatt ttccctggag aagctatgcc tgattgcaag
     3661 ctgctgggcg gcggggttcg cgatctgaat gttatggcgc gggaaggcga tacggggatg
     3721 ttgcgggtgc aaagtgccgt tgactggctt cctccgtcac ttgcgcaagc gggcctgttc
     3781 acgctgtgtg aaggggagtg gataagcggc aagaaaaggg tgtttgtcgc ggcaaatatg
     3841 ttgttatggc tggttgcacc tgatggcagg ccctggcgtt tcgtaccacg gaagaaagtc
     3901 tccgtcggtg agctggcggg ctggtggctt tattatctac gaggggaaaa atccttatga
     3961 gtgcattaac gctctggcga aataccacgc tggcgacgct ttccgctaac gattggggag
     4021 tgattgaaaa gggggcatta atcagccgtg gcgacactat tgtctggctt ggcaaggcca
     4081 cgcagatccc tcgcgaactg acggctgaca ttacagagga acacgacctg cagggtaagt
     4141 tgctgacacc cggtctggtg gattgtcata cacatctggt gtatggcggc cagagggcga
     4201 acgagtttga gatgcggttg caaggcgtag cttatgaaga tatcgccaga gcgggcggcg
     4261 ggatcttatc taccgtcaat gctacgcggg cggccagcga aacacaactg tttgaactgg
     4321 cggtgcagcg actacaaaac tggttgcgtg aaggcgtcag tacgctggaa atcaaatcgg
     4381 gttatggctt aacgctggaa gatgaagcgc gttgtttacg cgtgatccgc cgcttgcagc
     4441 aatctaccgg gttacatatt cagtctacgt ttctcggggc gcacagcctg ccgccagagt
     4501 ttgccgggcg cagtgatgat tacattacgg cgctttgcga ctggatgtgc gtgttgcatg
     4561 aacaggggct gattgatgca gttgatgctt tttgtgaaaa catcgccttt actccagagc
     4621 aggtacggcg cgttttcagt aaagcgcaaa gctatggatt acctgtaaaa ctgcatgccg
     4681 aacagctttc tgaccagcaa ggcgcggcgc tggcagcggc gttttctgca ctctcctgcg
     4741 atcatctgga gtacctgagc gagtcgggga tcgccgccat gaaagcggct ggaacagtgg
     4801 cggttttgct tcccggtgct tattacttcc tgcgcgaaac ccatctgccg ccgattgtcg
     4861 ctctgcgggc cgcaggtgtg ccgattgcta tctccacgga ccataatccc ggaacgtctc
     4921 ccaatatgtc attgccattg atgatcaata tggcctgtac gctgtttcgc atgacgccgc
     4981 tggaagccgt tcagggcgtt acgcgtaatg cggcaaaggc acttggactt attgaccggg
     5041 gtgaacttgc accgggatta cgggcggata tggcggtctg ggatcttaat catccacgtg
     5101 aactggctta ctggtttggg catcagcctt gccaggggct tattgtcggc ggaaaaagga
     5161 gttggtaatg aagcaaacat ttttgccgtg gagtgggcgt gttgactcgc aggaaaccgg
     5221 catcagcact cgctggcatc agcatgtgca accgtttagt gaacaaagcc acggcggttg
     5281 tacgctgatt ggttttgccg ttgatgacgg agtgcaacgt aatggtgggc gagcgggtgc
     5341 agcaggcgga ccgggcgcgt tgcgcagcat gttgggaaat atgccagtgc tctgtgaagg
     5401 cgctattttc gatatgggcg atgtacaaag cgaggaccac gcgctggaat ccgcacaaaa
     5461 tcgtctggcg gctaacgtat ctacagccat tgcgcgcggc agtttaccgg tggttctggg
     5521 gggcggtcat gaagtggcgt ggggaacatt tcaggggatt atgcagtcgc gtccggatat
     5581 tcagcggtta ctgattgtga accttgacgc gcattttgat ttacggatgg cggaacaagc
     5641 caattcaggt acgccgtttc gtcagatgca agagtggaac gcgcagtatg gcaaaccgtt
     5701 tcattatcgc gtgctgggaa taagtcgttt tgccaatact caggcgttat ttgatcgcgc
     5761 tgattgtctc ggtgtgcgtt attggctgga cgaatctctg caatttgaac gtggtttgca
     5821 tgagatcgct aatgcgctct cggcagatat tcaggcttgt gacgccattt atttaacgat
     5881 ttgtctcgat gttttaccag gttatcaggc gcccggtgtt tctgctccat caccgttagg
     5941 cgtgccgtta aatattactg aagccattgt gaatttaatc gccggtagcg agaagttgat
     6001 tgctgcggat attgccgaac tgaacccgga cctggaccgc gataatttaa ctgcgaaagt
     6061 tgccgctcgc ctggctgcca ctattgtccg gcgggggaaa acagatagaa caaattaaaa
     6121 cgttgtcgca gtaacccgtt gttaaactca tcatgataag gaaacacaat gaaaggattg
     6181 atacgaagag tcactgtcac cgttgtgctc tggagcgttt gctccattgc gatggcgaaa
     6241 tcaaccatta ctctggatgg cgaacatctt tccattgacc aggcctggtc aattgcatta
     6301 ggtgataacg acgtcaaaat cgcgccgaaa gctctgggca gaatggaaaa aagttatgat
     6361 ctggtgatga ccgccgcaca ttctggaaca cccgtttatg gtttaaccgt aggcgtgggg
     6421 ctaaataaag accagccgat atttgatgcc aaaggaaatt taacgcctga ggtgattgac
     6481 gcgtcgaaaa aatttaatgc tgccgcgctg cgcgcccatt ctgcgggcgt cggtccgatg
     6541 ttgccggatt atcttgcccg tctctcaatg gtgttacgtt taaatactat gttgcatggg
     6601 caaaccggcg cgcagcctta tattgccgag ttgtatgccg agtttattaa tcgaggcgtt
     6661 acgccgttaa ttccggcgcg gggaagtatc ggcgcagcgg atattatgct cgcttcacac
     6721 gttggtctgg tgatgatggg cgagtggaaa gcgcgggtta atggcgtgga aatgagtggt
     6781 ggcgatgcgc ttgtgaaagt ggggcttaaa ccactggtcc cgcagggtaa agatatgctg
     6841 gcgattttgt cgaacaacag tgtcggaaca gcatatgcaa ttgaagcggt acggtcggca
     6901 cgccaggtgc tgaacgtcag tccggtggtt tttgccatga gcctcgaagc gttgaatggc
     6961 aatgtcgcgc cggtactgcc gcagtcgatc gccgtgcgtc ctttcccgca gttggctgat
     7021 tccgctaaag agattcgcga tgcgttaagt ggttcttatt tatggcataa gcatgacaaa
     7081 cgtgcattgc aggatccgtt atcgttcaga acgacggtgt ataccatttc tgaggcaatg
     7141 cgcgcgttgc gcgatgctga agataccatt accgtgcaga tcaacagttc cgatgacaac
     7201 ccggcaaccg tgctgaatgc agacaaagcg tatcaggact ccagtcaggt cgcgcaatat
     7261 tttgttaaag atggggcaat cagcggtggg atcttcccga cggcgaattt cgaatcgtta
     7321 ccggttgcgc ttgccaccca gcgtctgacc gtggcgttgg tacatgtttc gcataacagc
     7381 atgcgtcgct cgctgcacct ggaagatgag cactttaccg gtttaacgcg cttcctgtcg
     7441 gcacccggta ataaaggtca cggcttcggt tcgctgcata ttccgtttgt cgcgctgcat
     7501 gcggaaaacg tcgatctcgc caatcctgtt tctttcgata ttcaaccggt tgccggaggt
     7561 atagaagata ccggtgccaa taatgaccac gcggccagaa gattgaaaca ggttgtcgat
     7621 aatctgaacg tgatttatgg cattgaactg atgcattccg cacaggctct cgatttacgg
     7681 ttgcaggccg atccacaact ggcattaggg aaatccacca aagcaatgtt taccgaatac
     7741 agaaaagtcg tgccgtttgt cgaccaggat cgggtcttta ccccagatat tgcagcttcg
     7801 caaaaattct tagaaggata tgctataaat caaaaataaa atttttgttg attgtttgtc
     7861 ataatatcca tagatatgat aattgctatc aatttaataa tcttcactta acttgaatca
     7921 taataatccg aagggcgttt tgcttttcgg attattattg tctgattgag acaattgtca
     7981 cgccaggctt accaggttat aaatatcgaa catgattttt ataaaatatt gattgctgct
     8041 ttggttgcca ttacttagca ataagtaatg gttttttgat agtttcaact atttttaagg
     8101 gaaggcatta tgcgaggaaa aatacctaaa acggaactgc tggtgacttt tgaggtcgtc
     8161 gcacgtcatg aaagttatac cagagcggca gaggagttag cgttaaccca aagtgcagta
     8221 ttcagacaag taagtgcgct ggaggaattt ttacgtactc cgttattttc acactctaaa
     8281 aaacgcattt ttcttaatga tgcagggaag tattacctgg ggatagtaaa agaaacatta
     8341 aataagctgg aacgcgatac caataccatt atgacctggc agcctacggt tcaggttatt
     8401 gaacttgccg ttaatcctac ttttagtacc cactggttaa tcccaaattt acatgaattc
     8461 acaaagttac atcccgatat tattgttaat attcattctt tagctaataa cggcgacttt
     8521 cttaatcggg agtacgatgc tgtcattatg cgcgaaaatt tttgcgcgcc ctgggcggaa
     8581 gtagagtatc tctttgaaga ggagattttg ccggtatgca gcggcagttt gcttgcaatg
     8641 tccgatcaaa aactgtcagt ggcagaactg cttactgagt taccacttct gcatcaaagc
     8701 acccgtatta ctggctggga agagtggttt gctttatctg gcgttagcag tccgctggtc
     8761 aataacggac cacgtttcga tttgctttca atgctgattg ccgccgtgcg ctctaatctc
     8821 ggcgtggcgc tgttaccacg gttcgctatt caacatgatt tggatagtgg cgatatggtg
     8881 attccctgtg atgtgcctat tcgtaccggt aatcgtttta ttatgacgtg gcaggaagag
     8941 aagtctgact caccgcactt gcagcaattt cgtgaatggt tgctggcgaa atcggtcgta
     9001 ccgcaggaga tgtaaaacct gcgcctggcg ggatgccagg cgcagttatt accagtcgat
     9061 acccggctgc gcctgaatgc cgttatcaaa agcatgtttg acggggcgga tttcgctgac
     9121 cgtatccgcc atttttaata tctgactgtg gcaaccgcgt ccggtgacaa tgacactttg
     9181 ttgtgccggg cggttttgca gagaagcgat cacttcttcg gtatccagat aatggtaagc
     9241 cagcatatag gtcagctcat caagcaccac taagtcgtaa cgcttgtcag ccagcatccg
     9301 tttgctttcc gaccagacct ctttcgccgc gtcgatatcc gcttgccggt tctgtgtctc
     9361 tcaggtaaaa ccggttccca taatatgaaa ctcaaccccg agcggctgga gaaggctgta
     9421 ttcgccgttg tcccattgcc ccttgatgta ctgcgcaacc cccaccgttt tgccatgacc
     9481 caccgcgcgc gtcacagtac caaacgcggc agtggatttc cctttgccat tgccggtgaa
     9541 aacaatcaaa atcccttttt tctctatcgc cgccgcgacg cgcgtatcga cctgttcctt
     9601 caatttctgc tggcgctgca catgccgttc agttgaaatt cgcgcttcca ttcattttcc
     9661 ttaatgtccc gcagggcaac tggcgcagcg gtgttgctgc tcaaactgac taaagaaatt
     9721 attgccttta tcatctacca ggatgaatgc gggcagattt tccacttcca tcatccacac
     9781 cgcttccata cccagctccg ggtattccag gcaacgcaga cttttgacat attcttgcgc
     9841 cagtaacgca gctgcaccgc caatacttcc cagattgaag ccgccatgtt tgtgacaggc
     9901 atcggtgacc tgctggctgc ggttaccttt cgataacatc accagactgc cgccagccgc
     9961 ctggaaggta tcgacataac cgtccattcg accgcccgtg gttggaccca gtgaaccgca
    10021 ggccatgttc tccggtgttt tcgccgggcc agcgtaatag acaatatgat gcttcaggta
    10081 atccggcatc ggttcgccgc tatccagccg cgcttttatt ttggcgtggg cgatatcgcg
    10141 cgccactacg atgggaccac ttaacgacac gcgggtgcct accggtaatc tggcgagatc
    10201 ctgcatcacg tcacgcaacg gacggtttag atccagttgt acatgttgcg cgtgattttc
    10261 ttcccgcagt gaggctggaa tatattgccc cggattgtgt tcgagttttt ccagccagat
    10321 accgtgcttg ttaatttttg ctttgatatt gcgatccgca gaacaggaga gcgccatagc
    10381 tatcgggcaa gagccaccgt gacgcggcag acgaatgacg cgaatatcat gagcgaaata
    10441 tttaccccca aattgcgcac caataccaaa ttgctgactg gcctcgagca acactttttc
    10501 cagctcaata tcacggaatg cttgtccctg ctcgtttccg ctggtgggca aattgtcgta
    10561 atatttcgtt gaggccagct tggcaacttt taaggtttga tcggctgaaa gccctccgac
    10621 gacaaaggcg atgtggtaag gcgggcaggc agcggtgccc agcgatttca ttttttcgat
    10681 taaaaatgcg gtcagttttt ctggttgcaa tagggatttg gtttcctgat aaagcgcggc
    10741 tttattggca gagccgcccc ctttattaat acagagaaaa tggtactcat caccagcgac
    10801 ggcgctgata tcaatctgcg ccggtagatt ggtttgcgta ttgacttcgg tatacatatc
    10861 cagtggcgca ttttgtgaaa agcgcagatt attttcctga aaagtggtgt aaatgccttt
    10921 gcttaaggct tcagcgtcgt tacctccggt ccatatctgt tgccctttac tggcaacaat
    10981 agttgcggtg ccggtatcct gacagttggg taatacccct tttgctgaga cttcagcatt
    11041 acgtaataac tgcaacgcaa cgtatttatc attactgctg gcctgcggat cgttaagaat
    11101 gctggcgacc tgttgcaaat gagcggaacg taagaaaaaa gaggcttcat aaaatgcctg
    11161 ccgggcaagc agcgttaatg cttcaggagc gatttttatt acttcttcgc cgtctaattc
    11221 cgttactgta atatgttgat cgctaattaa tgtatattct gtaccgtctt tattttgtag
    11281 aaacggttct tgccagataa atggtttgga catatttcac ttttcacctt aaacgttagt
    11341 tttacttaat tgccgtctaa cttcatgatc cggcttataa aaatgcgtag tcattggctt
    11401 ctgattgctt aagatccccc tcagggcaga gcaacgttcg attcattggg ttttaatgct
    11461 ttaccccgac agccctcgcc gaaatgttcg ccttcccacc gactcaccat cgcagcgccc
    11521 attgcgttgc tcatgacgtt tgtcgcggaa cgccccatat caaggaacgg atcaacgccc
    11581 atcagcaaga tcagccccgc ttccggaata ttgaactggt tgagcgtggc ggcgataacc
    11641 accattgagg cgcgtggtac gccagccatt cctttcgagg tcaacatcag gatcaacagc
    11701 atggtgattt gctcaccgat ggataaatgg atattgcagg cctgggcgat gaaaactgtg
    11761 gcgaaggagc agtaggccat tgatccaacg agattaaatg agtagccaat gggtaagaca
    11821 aagctggcaa ttttggggga aacgccaaat tgctccagtt tttcaagcgt tcccggaaaa
    11881 gccgcttcag aactggatgt ggtaaatgcc agcagggcgg gttccgaaag ggcgcgggtc
    11941 aggcgtctga tgcaggggcc gacataaacg atggccagac cgataagcag cacccaaagt
    12001 aataacatgg tgaaataaaa ttcacccata aagatcccgg cgctcaccat aactgccagt
    12061 cctcgttcag caatcaatgc tgaaatagca gcgaatacgg tcaggggagc gaagagcatg
    12121 acgtagccag tgagctttaa catggcatgt gccagcgaat ctaaggcgtg aacgatggcg
    12181 ctgcctttct caccaatcgc cgtcaggcta cagccgagga aaattgagaa caccacgatt
    12241 tgcaaaattt cattgtgcgc catggcatcg acaatgctgg tggggaaagc atgcgaaata
    12301 aatactttta gtgtaaaggg ttctgacgcg accactccgg tggtttcggc accgtgtgca
    12361 acaaaattaa ttcctgtgcc tggcatgaag aaatttaccg ttatcaagcc taaggcaatt
    12421 gacagcaatg aggcgcaaat aaataaaaag agtgttttag aaaaaatacg accaagggct
    12481 ttggcatctc ccattttagc tatacctacc accagggtag agaccactaa cggagcgata
    12541 atcattttta tcagtcgtaa gaaaatcgtc gtgaatatcg atatttcttg cgcatagagt
    12601 tttgcggttt ccggtgaagc agtgttattg agcactacgc cgataatcat tccaagtacc
    12661 agcgccaaaa gaatcatcgt ggttaaactt attttcttca ttttttcctc catcaggtgc
    12721 acggcgataa atcagaatca ggagaagtag atgcctgaat agagattcag gcatctacct
    12781 gctattacaa ccttacaaat agctgaagtg ttgaactgca ataagtgacg ggatgtcagt
    12841 tggctaaaag tattcggatt tttacaaatc gaaactcata tttaataaag gtgcatgttg
    12901 ctgtgcacca tagacatcat tgtcacctac attcccggag ataatatctc gtggcatgac
    12961 gatttttact gcgttagaag gatcaaacca gacaatacgg tgaataaagt caggttcaac
    13021 atgatataag cgcgcaatca gttctggggt taattgccct gatgatttaa ctcgctcata
    13081 gttttctttc gttttaaata aaatatctaa aaccagttcg taaggtccgg catttttcga
    13141 acgaatgact tgcgccagtg agacaattga ctgtttcatg cctgaactcc ttctggcgtc
    13201 acctgttcaa tatggaaatc aaaacgcaga gcgtcgttgg cttcaatcag gtgatatatg
    13261 gaaaattcgt ataccggccc gccctggata tcagaagggg agaacgggaa cgccagattg
    13321 cctgcggtag cgatgcggtt ttcatagccg tagtgcagca tggtagagcg caccagcgag
    13381 caaacgctat tggcaatttc ctgggtcggt gcaactacat caaggacaat ccccagctca
    13441 tgcccggcag tttgcatcgg ttcatggtcg cccatcaccc cgtttttgcc gtacaggtgg
    13501 aaattgatgc gaatgctgtc atcgtcgagc gacaggttac gtgaaacgct ggttttgact
    13561 tcatcgatga ttttatcgat cccggcgatc atgatcgggt cgcgcgttcc tgcgatggtc
    13621 agacagcgga agcccacccg tcgcgcacct tccagtttca gggcatacgg cgtttcttca
    13681 tgcttagaac cgctgacgta cacttcgccg tcattgaccg ctttaaatgt gcagcctttc
    13741 aggttcaaca cgccgccagg tccaggcagg aagtagggat cggatttctc atacagtgtg
    13801 tgtgcagccg ctgacgtttc ggtaaattta cgcttcggat taaatgtctt cagcgtaaag
    13861 ccgttgtcat caatgatgcc catcgcacag tcagagcctg agccgggcgt tgcggcgatt
    13921 gccgcgcatt caaggatttt cccacaatgc agcgccagac cttcatcaaa gccttgcatg
    13981 atcggaagcg cagcaaagca ggccgggtcg taagcgcgcc cgcccagcac cacttgcgcg
    14041 ccttctttca gcgcccgctg gaagggttcg atgcccattt gcgcaacgat atacgtactt
    14101 tcgtcaatcg cgtcgtgggt taacggcggg acaaaatcca gcgccgtgat tttgccgtta
    14161 tccagcacct ggtggacgat ggctttgtca acgtctgccg ggatcagcgc catcgagaac
    14221 gcgagttgct cttcccgggc aatctcatga attatttctc ggcaccactc caggtgtgga
    14281 gcggcaccag aaccgccggc cgttccgatc accaccggta tattattttg cacgcctgcg
    14341 gtgatcatat agcgcagatc gcgcttgacc cctgcgcgat cggtaaacgg tttgcccgct
    14401 ccgaggtagt gggggccagg atcggaagag cctgcatcaa cggcgatcag atcgggcgat
    14461 tctgccatcg ctttgcggaa gctctcttcc gggaatccat acccgaggat tgccgttggc
    14521 gataagactt taaaagaacg agccatttgt taatccttag cctgcaacag cgcgatagta
    14581 cgattcattt cgttgaagac gatatcgagg ccttcgtcaa agcccatccc tggctttacc
    14641 agcatacgca tagggcgagc ggcaagggcg acgtggacac aggtgcgggc actgacatca
    14701 gtttcattgc aggtgccgcc ctggtacgct tccatgctgt ggctgttgca gtaaagaacc
    14761 gcatcgacga tgttgtgaat actgcccaga tccggggttt tgatttgcac catgtggcaa
    14821 ctggcggcat cagtgaaatc aacaatatcc tggtaggtgt tacaccattc atcggccaca
    14881 attttcacgc cggaaccgag gcgcgtcagc tctttggtaa tcgcggtcag caggcgaatt
    14941 tgatcgggct tgttaccggc atcgaccggc ccttcaatgt agagcggcag gccttgcgct
    15001 tctttttcca ggctggcgat gtattgcgca cagcgaagcg gatccatatc gaagatcaga
    15061 ccgatagtgc cgtatacatc gatgtgcagg gttgggtggt agcgtgcgct ggtgcgcttg
    15121 ctcagaatac gatccgacag ccagcggaca tattcgcgca gtttttcacc tttaaagccc
    15181 agtttctctt cgacgttatt aatcagtgca tggggcagca cgtcgatgcc cttaaggatc
    15241 atcttatcga cggcgatata tcgatcgtcc ccgctctgac caaataatgg aatggattcc
    15301 gccacgcgtg gcaactgcca ttcatcatag accacttcag ttttcagacg gccggttgcc
    15361 agcgcggtag catcaagcag cgcctgtgat aatccgtagc gcacggcggt atgcagcaag
    15421 ttgccgtcaa tacgcaattt gtcgaagaaa cgggcattcg gcaggaaagc atccacatcg
    15481 cggcctacca gtaatggctt gatatggtcg ttgaggaacg gaataaagtg ctctgcgagg
    15541 aacagtggat cgcgaccacc tgccccggaa tactgtacgg cagcacagtc acctacggcg
    15601 accgcgccgt tttccagaat caactgtacc gatacgcact ccccggcctg acgaacggcg
    15661 ttaaacccct gtgttaccgg ctccccggta taaaaaaagc cgtcatgacc cgctccgttt
    15721 tttatcgcct gctggtcatc gaaatagaat gaggagtagc cagcggtgaa cagagcctgt
    15781 tttattttca ttatggtctt cctattaatt tactgtggga tacagcattg atgtcatcta
    15841 caaccatctg gaatgtcggt tggcgtcctt caaagcgtgc gcgttccgca acgtaatcgt
    15901 ggcggaggtc gagaatatct tttggcaatg gaacggctcc ggcttccagt acgcgtatcg
    15961 cgccggtgtt gtcacggacc ggaagaattt tgcccgcgtt gcaggcggct ggcgcaaacg
    16021 gcacatccag tacgcccgat tcaaatgcca gcaccgtacc gcgcgcaata tcaccattac
    16081 ccagttcgaa cactttattc agtaccgcgc gaacctcgct cttaatcagt tcaatttcca
    16141 gttcaaccgc agggcacggc gggaatttct gctcgttgac catgttgagc atctggcggg
    16201 aggctttcag cccctgaatg ttggcagcgg cagtcgggat gccccaggct tcgtgcggac
    16261 ttttggtgat gactttggtg gcaccagaca tccccgcgac ggctgcgccc caggagataa
    16321 tagcgaacgc tttcgattcg tcttccggaa agccgcccat ccactggtga aacacggtac
    16381 ttaattcata gtcggtatag ccatagctct gaaaatattc gtgtgcaagt tcacgcagag
    16441 actggatcgc cgcaacatcc tgcgtcaggc tgccgacctg tccataacca acggtgatag
    16501 atttcacacc ctgttccagc gccagtaatc cttcgattat cgcgatagag tgcgagataa
    16561 acggcgggat cagggtaccc gttagtgggc caaacggttc gcggttgatg cggatcccgt
    16621 gttcttcata catccccatt aaacggtcgc agtactgcca gtcgcggatc gatttttcca
    16681 gcgttacgcg cttggcatac ggaatattgt aggaaatgcc gccgccttca taactggtaa
    16741 agccgctggc catcgagatt tcagccagca gacgcgcatc tggcgtgccg tggcggatct
    16801 gtagcggttt ttgcagagtt tcggtgaggc gacggcaagc tgcgacgccg tggttaacga
    16861 ccggtaaacc gttcagttta gaggttccgg cttcgatgga ttttttaatc cctacagccg
    16921 cttcttcgta ccgattcaga cgggtatatg cgtcgatggt gctcggcagc agatcgcatt
    16981 cttcttgtag tgttttcagt agttcgatgt gttcgtccat cagcgccacg cctgcgcgcg
    17041 gttggctaag agttttacct tccttgtctg ctttcagcag ggcaagagag aagcgtttat
    17101 gctcaggaat ggtttgttgg tatttaacgc catcttcaaa gttttcaaca tccttgccgg
    17161 tttcccaggt tttcagtacc tgttgccgct cggtcatgaa ttcgtcatgg gttaatttct
    17221 tatttcgaag ttccattgat tgcagcctta attgttatag ggttaagcat tgaatactgg
    17281 tgcgcgcggc ggccagcgga tcgactctgg cgacgtttgc cagcagtggt aatagccccc
    17341 gggaatcgcg gtaatattca aattcggtcg gtaagagaat gcgtttaccg tcgtcgttta
    17401 actcgcggta tttcaaccag tgatgcatat cgaactgact ggcacgcgag agccatccgc
    17461 cggatccgac gactttacgc acggttgtca ggtcacgtcc catctgtaaa tcgacattgc
    17521 cgacgcaggt gcagacctct tttttggtgc ccgcatgtct ttcggtggca taacccacac
    17581 acagtccggc caggactgta tcgaaatatt tttcttctgc attcgcgggt aagtagtcgg
    17641 gatgagcgac tagatgacgg aggtaatgat aaaaagcgtc cagctgtgcg ggttgctgag
    17701 caaaattcac attgactaac tctttcgcac tttcaccaac caccattgcc gagacgcgca
    17761 ttcccagatc gccttccacc gtccgtttca cgaagggttc cggtacgccg tgtaaaacgg
    17821 tgtcgggcga gagcgtgttg gcacaggcgg aatagacatc ggtggttgcg ccacccatgt
    17881 cgatcagcat gaactctttc cagctgtgat cgacattact gattgcctta accagttcaa
    17941 agactgtcca cggtgtcggc attggttctt cgcctgtttt atcaacaacg acatccagcc
    18001 ctttcccttt aatgatgcgt ttaaggaata tgtcgcagat agcctggcgt gcagctaaag
    18061 ggttcggatg gtcaagatcg ggcagaacgt tgtcgacgat ggtcaggtct ttatgcccta
    18121 ggatctcctg cacctcgtcc tgaatatccc ggtttccggc ataaataatg gcgcagtcga
    18181 gtttggattc tgccagcaca cgggcgttat tcaggccgta actttcttct ccgccgtcgg
    18241 tgccgccggt gaacaagaga atatcgggct gcgtttcttc cagtgcctgg atatcacggc
    18301 ggttcagctt gtaggagtaa tattgcgcaa ttttagcccc cgcagagtga gcggttactt
    18361 tcgcggtttc cagggtgata gaaggcacca atcccattgc ggcaaccgcc agcccacctt
    18421 tggcagagga ggaatacttc aatgcaacct caccgttgtt aaacaggggg agggcattat
    18481 ctacgtttaa caccaggttc aggctggaga aaaacccctt cgccagatga tgggtggtgg
    18541 ttggggtcag tacgtggtta accaacgtta acgcgtcccc ctcccgggcg aagagggctg
    18601 ctttggtcca cgtcgatcca atatcgacag agacgatttg catcagattg cctcttcaag
    18661 aatacgagta tcaacgtcat gacgttggtt gatatcgtgt gccatcagct gacaaacatc
    18721 ttctaagtca tgacttgggg caaagacgcg atcaaatccc atctctttga atttggtttc
    18781 cacgtcagcg aagtcatgtt ttccgaccac caggttaccg cccacataga gcaggatgtc
    18841 ccctagtcca cgctcgatgc agcgttcgcg catgcccaga cagtcgatat cgccatgccc
    18901 atagatagag gagacgacaa tcgcgtcagc gccagtttca atggccgcat caatatattc
    18961 gtcctggctg accattacgc ccagattaat gactctgaag ccatggttgc taaaaacgcg
    19021 gtccagaact ttattgccta ctgcatggca gtccgcgcca ataacgccaa tcacaagtgt
    19081 tgctttcttc atgggtaatc ctttgtaaga cagagagtaa aataagttac acacgtcgta
    19141 tttatggccg ttcataacgg cacaggttta atatcacagg agtgtcttta tctgaccgta
    19201 atgttgcaat tgatctattt tcaaaatgtc tttcgggaaa tgattgttta aagtatgttt
    19261 ttaaattctc atgttaattc agtgtgttat gtcaactaat gtcatgaatg ttaaattttt
    19321 aaaattaact tgatttggtg tattgaggta tttgtgatct acttctaatt tgcattttag
    19381 tgatatgggt ttagccatga gtaaatgcat ttcataaaat ttaagtcgaa tttcactgca
    19441 attcatctct gcttaatgta aaaataatgt tgaaaataac aaatggttaa tgattcatgc
    19501 gaattatgac cttagttagc tcttttgatt tttcgtaaaa aagagaggta catgaaggtg
    19561 ctaccagtat gagtaacgtt aatcaaaggt tttattacgt ctggcaataa cgcaggccat
    19621 tttcgcgact gggtggattt aatcagtata atcctcatac aatagttcac gattaactga
    19681 accgttaacg gggatttggt gttgaaattt agaaatggcg gagtcaatta atgaagacaa
    19741 catcgaaaaa atgacagtgt cagaattaat ttcaattaat ccttctcgtt gttgaccaaa
    19801 aaagatattt atcttgattt catttgtact acggcaatca atatgtagta atttttgatc
    19861 gctgagattt tctgtttcat aaatgttttt ggcgatagtc ggatgtattg atgccagaca
    19921 tctgctcaga taagccagat cctttaggga acaccccgct gagtagagga tgtcagagaa
    19981 tttttgtgtg tcaactgttg tctctgaagc gtatgttgca ttgacaggaa gggtgttgaa
    20041 agagatttga gatgggatca ttatttaaat ctttccgtga gtaataaaaa ttaatccccg
    20101 ggcattgttt agcaatattt gccacaggga atatataaaa attaaagtat ttgattggca
    20161 tcggttaact gatcaataac cagtgccaga ttggtaaaca ttttgaaaaa gcgatactgg
    20221 ctcggaatat ctctttcaaa gacgaaacat tcaatgtcat tgtttgaaaa ataaaggact
    20281 agtgttgctg attcgtcagg aaaaatatgg aaatatatct ggttaccaga aggaggatag
    20341 tccagaagaa gggtatcttt gcccgtcaca tacctgttgt ggtcgtggat gctacgctca
    20401 cacttcatca gaggtgtcat gatactcatg tattcatctg atgttaatat attaaa
//
LOCUS       DADXDL010000092        20313 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.092, whole genome shotgun sequence.
ACCESSION   DADXDL010000092 DADXDL010000000
VERSION     DADXDL010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.092"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            31..1485
                     /locus_tag="IRB70_003797"
     CDS             31..1485
                     /locus_tag="IRB70_003797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415044.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative allantoin permease"
                     /protein_id="HBC0633655.1"
                     /translation="MEHQRKLFQQRGYSEDLLPKTQSQRTWKTFNYFTLWMGSVHNVP
                     NYVMVGGFFILGLSTFSIMLAIILSAFFIAAVMVLNGAAGSKYGVPFAMILRASYGVR
                     GALFPGLLRGGIAAIMWFGLQCYAGSLACLILIGKIWPGFLTLGGDFTLLGLSLPGLI
                     TFLLFWLVNVGIGFGGGKVLNKFTAILNPCIYIVFGGMAIWAISLVGLGPIFDYIPSG
                     IQKAENSGFLFLVVINAVVAVWAAPAVSASDFTQNAHSFREQALGQTLGLVVAYILFA
                     VAGVCIIAGASIHYGADTWNVLDIVQRWDSLFASFFAVLVILMTTISTNATGNIIPAG
                     YQIAAIAPTKLTYKNGVLIASIISLVICPWKLMENQDSIYLFLDIIGGMLGPVIGVMM
                     AHYFMVMRGQINLDELYTAAGDFKYYDNGFNLTAFSVTLVAVILSLGGKFIPFMEPLS
                     RVSWFVGVIVAFAAYALLKKRTAAEKTGEQKVTG"
     gene            1546..2907
                     /gene="allB"
                     /locus_tag="IRB70_003798"
     CDS             1546..2907
                     /gene="allB"
                     /locus_tag="IRB70_003798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoinase AllB"
                     /protein_id="HBC0633656.1"
                     /translation="MSFDLIIKNGTVILENEARVVDIAVKGGKIAAIGQDLGDAKEVM
                     DASGLVVSPGMVDAHTHISEPGRSHWEGYETGTRAAAKGGITTMIEMPLNQLPATVDR
                     ASIELKFDAAKGKLTIDAAQLGGLVSYNIDRLHELDEVGVVGFKCFVATCGDRGIDND
                     FRDVNDWQFFKGAQKLGELGQPVLVHCENALICDELGEEAKREGRVTAHDYVASRPVF
                     TEVEAIRRVLYLAKVAGCRLHVCHISSPEGVEEVTRARQEGQDVTCESCPHYFVLDTD
                     QFEEIGTLAKCSPPIRDLENQKGMWEKLFNGEIDCLVSDHSPCPPEMKAGNIMKAWGG
                     IAGLQSCMDVMFDEAVQKRGMSLPMFGKLMATNAADIFGLQQKGRIAPGKDADFVFIQ
                     PNSSYVLTNDDLEYRHKVSPYVGRTIGARITKTILRGDVIYDIEQGFPVAPKGQFILK
                     HQQ"
     gene            2964..4265
                     /locus_tag="IRB70_003799"
     CDS             2964..4265
                     /locus_tag="IRB70_003799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308602.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil/xanthine transporter"
                     /protein_id="HBC0633657.1"
                     /translation="MFNFAVSRESLLSGFQWFFFIFCNTVVVPPTLLSAFQLPQSSLL
                     TLTQYAFLATALACFAQAFCGHRRAIMEGPGGLWWGTILTITLGEASRGTPINDIATS
                     LAVGIALSGVLTMLIGFSGLGHRLARLFTPSVMVLFMLMLGAQLTTIFFKGMLGLPFG
                     IADPNFKIQLPPFALSVAVMCLVLAMIIFLPQRFARYGLLVGTITGWLLWYFCFPSSH
                     SLSGELHWQWFPLGSGGALSPGIILTAVITGLVNISNTYGAIRGTDVFYPQQGAGNTR
                     YRRSFVATGFMTLITVPLAVIPFSPFVSSIGLLTQTGDYTRRSFIYGSVICLLVALVP
                     ALTRLFCSIPLPMSSAVMLVSYLPLLFSALVFSQQITFTARNIYRLALPLFVGIFLMA
                     LPPVYLQDLPLTLRPLLSNGLLVGILLAVLMDNLIPWERIE"
     gene            4287..5432
                     /gene="glxK"
                     /locus_tag="IRB70_003800"
     CDS             4287..5432
                     /gene="glxK"
                     /locus_tag="IRB70_003800"
                     /EC_number="2.7.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 3-kinase"
                     /protein_id="HBC0633658.1"
                     /translation="MKIVIAPDSFKESLSAEKCCQAIKAGFSTLFPDAHYICLPIADG
                     GEGTVDAMVAATGGNIVTLEVCGPMGEKVNAFYGITGDGKTAVIEMAAASGLMLVAPE
                     KRNPLLASSFGTGELIRHALDNGIRHIILGIGGSATVDGGMGMAQALGVRFLDAYGQV
                     LAANGGNLARVASIEMDECDPRLANCHIEVACDVNNPLVGARGAAAVFGPQKGATPEM
                     VEELEQGLQNYARVLQQQTEINVCQMAGGGAAGGMGIAAAVFLNADIKPGIEIVLNAV
                     NLAQAVQGAALVITGEGRIDSQTAGGKAPLGVASVAKQFNVPVIGIAGVLGDGVEVVH
                     QYGIDAVFSILPRLAPLAEVLASGETNLFNSARNIACAIKIGQGIKN"
     gene            complement(5561..6346)
                     /gene="allE"
                     /locus_tag="IRB70_003801"
     CDS             complement(5561..6346)
                     /gene="allE"
                     /locus_tag="IRB70_003801"
                     /EC_number="3.5.3.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(S)-ureidoglycine aminohydrolase"
                     /protein_id="HBC0633659.1"
                     /translation="MGYLNNVTGYRDDLLANRAIVKHGNFALLTPDGLVKNIIPGFEN
                     CDATILSTPKLGASFVDYLVTLHQNGGNQQGFGGEGIETFLYVISGNITAKAEGKTFT
                     LSEGGYLYCPPGSLMTFVNAQAEDSQIFLYKRRYIPVEGHAPWLVSGNASELERIHYE
                     GMDDVILLDFLPKELGFDMNMHILSFAPGASHGYIETHVQEHGAYILSGQGVYNLDNN
                     WIPVKKGDYIFMGAYSLQAGYGVGRGEAFSYIYSKDCNRDVEI"
     gene            complement(6357..7592)
                     /gene="allC"
                     /locus_tag="IRB70_003802"
     CDS             complement(6357..7592)
                     /gene="allC"
                     /locus_tag="IRB70_003802"
                     /EC_number="3.5.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="allantoate deiminase"
                     /protein_id="HBC0633660.1"
                     /translation="MITHFRQAIEETLPWLSSFGADPTGGMTRLLYSPEWLETQQQFK
                     KRMAASGLETRFDEVGNLYGRLNGSEYPQEVILSGSHIDTVVNGGNLDGQFGALAAWL
                     AIDWLKTQYGAPLRTVEVVAMAEEEGSRFPYVFWGSKNIFGLANPDDVRNICDAKGNS
                     FVDAMKACGFTLPNAPLTPRQDIKAFVELHIEQGCVLESNGQSIGVVNAIVGQRRYTV
                     TLNGESNHAGTTPMGYRRDTVYAFSRICHQSVEKAKKMGDPLVLTFGKVEPRPNTVNV
                     VPGKTTFTIDCRHTDTAVLRDFTQQLENDMRAICDEMDIGIDIDLWMDEEPVPMNKEL
                     VATLTELCESEKLNYRVMHSGAGHDAQIFAPRVPTCMIFIPSINGISHNPAERTNITD
                     LAEGVKTLALMLYQLAWQK"
     gene            complement(7614..8663)
                     /gene="allD"
                     /locus_tag="IRB70_003803"
     CDS             complement(7614..8663)
                     /gene="allD"
                     /locus_tag="IRB70_003803"
                     /EC_number="1.1.1.154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate dehydrogenase"
                     /protein_id="HBC0633661.1"
                     /translation="MKISRETLHQLIENKLCQAGLKREHAATVAEVLVYADARGIHSH
                     GAVRVEYYAERISKGGTNREPEFRLEETGPCSAILHADNAAGQVAAKMGMEHAIKTAQ
                     QNGVAVVGISRMGHSGAISYFVQQAARAGLIGISMCQSDPMVVPFGGAEIYYGTNPLA
                     FAAPGKGDEILTFDMATTVQAWGKVLDARSRNMSIPDTWAVDKNGAPTTDPFAVNALL
                     PAAGPKGYGLMMMIDVLSGVLLGLPFGRQVSSMYDDLHAGRNLGQLHVVINPNFFSSS
                     ELFRQHLSQTMRELNAITPAPGFNQVYYPGQDQDIKQRKTAVEGIEIVDDIYQYLISD
                     ALYNTSYETKNPFAQ"
     gene            8980..10647
                     /locus_tag="IRB70_003804"
     CDS             8980..10647
                     /locus_tag="IRB70_003804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase FdrA"
                     /protein_id="HBC0633662.1"
                     /translation="MIHAFIQKGCFQDSVSLMIISRKLSESENVDDVSVMMGTPANKA
                     LLDTTGFWHDDFNNATPNDICVAIRSEAADAGIAQAIMQQLEEALKQLAQGSGSSQAL
                     TQVRRWDSACQKLPDASLALISVAGEYAAEVANQALDRNLNVMMFSDNVTLEDEIQLK
                     TRARDKGLLVMGPDCGTSMIAATPLAFANVMPEGNIGVIGASGTGIQELCSQIALAGE
                     GITHAIGLGGRDLSREVGGISALTALEMLCTDAKSEVLAFVSKPPAEVVRLKIVNAMK
                     ATGKPTVALFLGYTPAVARDENVWFASSLDEAARLACLLSRVTARRNAIAPVSSGFIC
                     GLYTGGTLAAEAAGLLAGHLGVEADDTHQHGMMLDADGHQILDLGDDFYTVGRPHPMI
                     DPTLRNLLIADLGAKPQVRVLLLDVVIGFGATADPAASLVSAWQKACAARPDNQPLYA
                     IATVTGTERDPQCRSQQIATLEDAGIAVVSSLPEATLLAAALIHPLSPATQQHTPSLL
                     ENVAVINIGLRSFALALQSASKPVVHYQWSPVAGGNKKLARLLERLQ"
     gene            10657..11916
                     /locus_tag="IRB70_003805"
     CDS             10657..11916
                     /locus_tag="IRB70_003805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009029994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1116 domain-containing protein"
                     /protein_id="HBC0633663.1"
                     /translation="MFTSVAQANAAVIEQIRRARPHWLDVQPASSLISELNEGKTLLH
                     AGPPMRWQEMTGPMKGACVGACLFEGWAKDEAQALAMLDQGEVNFIPCHHVNAVGPMG
                     GITSASMPMLVVENVTDGNRAYCNLNEGIGKVMRFGAYGEDVLTRHRWMRDVLMPVLS
                     AALGRMERGIDLTAMMAQGITMGDEFHQRNIASSALLMRALAPHIARLDHDKQHIAEV
                     MDFLSVTDQFFLNLAMAYCKAAMDAGAMIRAGSIVTAMTRNGNMFGIRVSGLGERWFT
                     APVNTPQGLFFTGFSQEQANPDMGDSAITETFGIGGAAMIAAPGVTRFVGAGGMEAAR
                     AVSEEMAEIFLERNMQLQIPGWDFQGACLGLDIRRVVETGITPLINTGIAHKEAGIGQ
                     IGAGTVRAPLACFEQALEALAESMGIG"
     gene            11927..12742
                     /locus_tag="IRB70_003806"
     CDS             11927..12742
                     /locus_tag="IRB70_003806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308609.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2877 domain-containing protein"
                     /protein_id="HBC0633664.1"
                     /translation="MTIIHPLLASRSAPNYRQSWRLAGVWRRAINLMTESGELLTLHR
                     QGSGFGPGGWVLRRAQFDALCGGLCGNERPQVVVQGIRLGRFTVKQPQRYCLLRITPP
                     AHPQPLAAAWMQRAEETGLFGPLALAASDPLPAELRQFRHCFQAALNGVKTDWRHWLG
                     KGPGLTPSHDDTLSGMLLAAWYYGALDARSGRPFFACSDNLQLVTTAVSVNYLRYAAQ
                     GYFASPLLHFVHALSCPKRTAAAIDSLLALGHTSGADTLLGFWLGQQLLQGKP"
     gene            12739..13632
                     /locus_tag="IRB70_003807"
     CDS             12739..13632
                     /locus_tag="IRB70_003807"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBC0633665.1"
                     /translation="MKTLVVALGGNALLQRGEALTAKNQYRNIASAVPALARLARSYR
                     LAIVHGNGPQVGLLALQNLAWKEVEPYPLDVLVAESQGMIGYMLAQSLSAQPQMPPVT
                     TVLTRIEVSPDDPAFLQPEKFIGPVYQPEEQEALEAAYGWQMKRDGKYLRRVVASPQP
                     RKILDSEAIELLLKEGHVVICSGGGGVPVTKDGVGSEAVIDKDLAAALLAEQINADGL
                     VILTDADAVYENWGTPQQRAIRHATPDELAPFAKADGSMGPKVTAVSGYVRSRGKPAW
                     IGALSRIEETLAGEAGTCISL"
     gene            complement(13865..14932)
                     /gene="purK"
                     /locus_tag="IRB70_003808"
     CDS             complement(13865..14932)
                     /gene="purK"
                     /locus_tag="IRB70_003808"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706400.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBC0633666.1"
                     /translation="MKQVCVLGNGQLGRMLRQAGEPLGIAVWPVGLDAEPAAVPFQQS
                     VITAEIERWPETALTRELARHPAFVNRDVFPIIADRLTQKQLFDKLHLPTAPWQLLAD
                     RSEWPAVFKRLGELAIVKRRTGGYDGRGQWRLRADETEQLPTECYGECIVEQGINFSG
                     EVSLVGARGFDGSTVFYPLTHNLHQDGILRTSVAFPQANAQQQAQAEEMLSAIMQELG
                     YVGVMAMECFVTPQGLLINELAPRVHNSGHWTQNGASISQFELHLRAITDLPLPQPVV
                     NSPSVMINLIGSDVNYDWLKLPLVHLHWYDKEVRPGRKVGHLNLTDSDTSRLTATLEA
                     LIPLLPPEYASGVIWAQSKFS"
     gene            complement(14929..15438)
                     /gene="purE"
                     /locus_tag="IRB70_003809"
     CDS             complement(14929..15438)
                     /gene="purE"
                     /locus_tag="IRB70_003809"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBC0633667.1"
                     /translation="MSSRNNPARVAIVMGSKSDWATMQFAAEIFEILNVPHHVEVVSA
                     HRTPDKLFSFAESAEENGYQVIIAGAGGAAHLPGMIAAKTLVPVLGVPVQSAALSGVD
                     SLYSIVQMPRGIPVGTLAIGKAGAANAALLAAQILATHDKELHQRLNDWRKAQTDEVL
                     ENPDPRGAA"
     gene            complement(15556..16278)
                     /gene="lpxH"
                     /locus_tag="IRB70_003810"
     CDS             complement(15556..16278)
                     /gene="lpxH"
                     /locus_tag="IRB70_003810"
                     /EC_number="3.6.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-2,3-diacylglucosamine diphosphatase"
                     /protein_id="HBC0633668.1"
                     /translation="MATLFIADLHLCAEEPAITAGFLRFLAGEARKADALYILGDLFE
                     AWIGDDDPNPLHRQMAAAIKAVSDSGVPCYFIHGNRDFLLGKRFARESGMTLLPEEKV
                     LELYGRRVLIMHGDTLCTDDAGYQAFRAKVHKPWLQTLFLALPLFVRKRIAARMRANS
                     KEANSSKSLAIMDVNQNAVVSAMEKHQVQWLIHGHTHRPAVHELIANQQPAFRVVLGA
                     WHTEGSMVKVTADDVELIHFPF"
     gene            complement(16281..16775)
                     /gene="ppiB"
                     /locus_tag="IRB70_003811"
     CDS             complement(16281..16775)
                     /gene="ppiB"
                     /locus_tag="IRB70_003811"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017465360.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase B"
                     /protein_id="HBC0633669.1"
                     /translation="MVTFHTNHGDIVIKTFDDKAPETVKNFLDYCREGFYNNTIFHRV
                     INGFMIQGGGFEPGMKQKATKEPIKNEANNGLKNTRGTLAMARTQAPHSATAQFFINV
                     VDNDFLNFSGESLQGWGYCVFAEVVEGMDVVDKIKGVATGRSGMHQDVPKEDVIIESV
                     TVSE"
     gene            16949..18334
                     /gene="cysS"
                     /locus_tag="IRB70_003812"
     CDS             16949..18334
                     /gene="cysS"
                     /locus_tag="IRB70_003812"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005125243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBC0633670.1"
                     /translation="MLKIFNTLTRQKEEFKPIHAGEVGMYVCGITVYDLCHIGHGRTF
                     VAFDVVARYLRFLGYKLKYVRNITDIDDKIIKRANENGESFVALVDRMIAEMHKDFDA
                     LNILRPDMEPRATHHIAEIIELTEQLIAKGHAYVADNGDVMFDVPTDPTYGVLSRQDL
                     DQLQAGARVDVVDDKRNPMDFVLWKMSKEGEPSWPSPWGAGRPGWHIECSAMNCKQLG
                     NHFDIHGGGSDLMFPHHENEIAQSTCAHDGQYVNYWMHSGMVMVDREKMSKSLGNFFT
                     VRDVLKYYDAETVRYFLMSGHYRSQLNYSEENLKQARAALERLYTALRGTDKTVAPAG
                     GEAFEARFIEAMDDDFNTPEAYSVLFDMAREVNRLKAEDMAAANAMASHLRKLSAVLG
                     LLEQEPEAFLQSGAQADDSEVAEIEALIQQRLDARKAKDWAAADAARDRLNEMGIVLE
                     DGPQGTTWRRK"
     gene            complement(18370..18891)
                     /locus_tag="IRB70_003813"
     CDS             complement(18370..18891)
                     /locus_tag="IRB70_003813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBC0633671.1"
                     /translation="MPTVITHAAVPLCIGLGLGSKVIPPRLLFAGIVLAMLPDADVLS
                     FKFGVAYGNVFGHRGFTHSLVFAFVVPLLCVLIGRRWFRAGLIRCWLFLTVSLLSHSL
                     LDSVTTGGKGVGWLWPWSDERFFAPWQVIKVAPFALSRYTTPYGHQVIISELMWVWLP
                     GMLLMGMLWWRRR"
     gene            complement(18999..19211)
                     /gene="ybcJ"
                     /locus_tag="IRB70_003814"
     CDS             complement(18999..19211)
                     /gene="ybcJ"
                     /locus_tag="IRB70_003814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308617.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated protein YbcJ"
                     /protein_id="HBC0633672.1"
                     /translation="MATFSLGKHPHVELCDLLKLEGWSESGAQAKIAIAEGQVKVDGA
                     VETRKRCKIVAGQTVSFAGHSVQVVA"
     gene            complement(19213..20079)
                     /gene="folD"
                     /locus_tag="IRB70_003815"
     CDS             complement(19213..20079)
                     /gene="folD"
                     /locus_tag="IRB70_003815"
                     /EC_number="1.5.1.5"
                     /EC_number="3.5.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase
                     FolD"
                     /protein_id="HBC0633673.1"
                     /translation="MAAKIIDGKTIAQQVRSEVAQKVQARIAAGLRAPGLAVVLVGSN
                     PASQIYVASKRKACEEVGFVSRSYDLPETTSEAELLELIDALNADNTIDGILVQLPLP
                     AGIDNVKVLERIHPDKDVDGFHPYNVGRLCQRAPRLRPCTPRGIVTLLERYNIDTFGL
                     NAVVIGASNIVGRPMSMELLLAGCTTTVTHRFTKNLRHHVENADLLIVAVGKPGFIPG
                     DWIKEGAIVIDVGINRLENGKVVGDVVFEDAAKRASYITPVPGGVGPMTVATLIENTL
                     QACVEYHDPQGE"
BASE COUNT         4625 a         5165 c         5582 g         4941 t
ORIGIN      
        1 ttattcgata cgtgaaatta agagggattt atggaacatc agagaaaact attccagcaa
       61 cgcggctata gcgaagatct attgccgaaa acgcaaagcc agcggacctg gaaaacattt
      121 aactatttta ccttatggat gggttcggtt cataacgttc ccaattatgt gatggtcggt
      181 ggctttttta ttctcggctt gtctaccttt agtattatgc tggcaattat cctcagcgcc
      241 tttttcattg ccgcggtaat ggtattaaac ggtgctgcgg gcagtaaata cggcgtaccg
      301 tttgccatga tcctgcgtgc ttcttatggc gtacgtggcg cactgtttcc cggattatta
      361 agaggcggga ttgctgccat tatgtggttt ggcctgcaat gttacgccgg atcgctggcc
      421 tgcttgatcc tgattggcaa aatctggccg ggatttttaa ctctcggtgg tgatttcact
      481 ctgttaggcc tttctctacc gggcttaatt actttcttac tcttctggct ggtcaacgtt
      541 ggtataggtt ttggcggtgg caaagtttta aataaattca ctgccattct taacccgtgc
      601 atctatatcg ttttcggcgg tatggcgatt tgggcgattt cgctggtcgg gctcggtcca
      661 atctttgact acattccgag cggtattcag aaagcagaaa acagtggatt cttgttcctg
      721 gtggtgatta acgcggtagt tgcggtctgg gcggcaccgg cggtgagcgc atccgacttt
      781 acgcaaaacg cccactcgtt tcgtgagcaa gcgctggggc aaacgctggg tttagttgtg
      841 gcctatattc tgtttgcggt cgccggggta tgtattattg ccggagccag tattcactac
      901 ggcgctgaca cctggaacgt gctggatatt gttcagcgtt gggacagcct gtttgcctcg
      961 ttctttgcgg tactggttat tctgatgacg accatttcca ctaacgccac cggtaatatt
     1021 attccggccg gttatcagat tgccgctatt gcaccgacga aactgaccta taaaaacggc
     1081 gtactgattg ccagtattat cagcctggtg atctgcccgt ggaaattaat ggaaaatcag
     1141 gacagtattt atctgttcct cgatattatc ggcggaatgc tgggtccggt aattggtgtc
     1201 atgatggcgc attattttat ggtgatgcgc ggacaaatta atcttgatga actgtatacc
     1261 gcagcaggtg atttcaaata ttacgataac ggctttaacc ttaccgcgtt ctcagtaact
     1321 ttggtcgccg ttattttatc tctcggtggt aaatttattc cgttcatgga gcctttatca
     1381 cgcgtttcat ggtttgtcgg cgttattgtc gcattcgctg cctacgcgtt attaaaaaaa
     1441 cgtacagcag cagaaaaaac aggagaacaa aaagtcacag gttaattaat cccgatattg
     1501 aacattgagt taaaaaacca atctgtattt tacaaggagt ttgttatgtc ttttgattta
     1561 atcattaaaa acggcaccgt tattttagaa aacgaagctc gcgttgtaga tatcgccgtt
     1621 aaaggcggaa aaattgctgc tatcggtcag gatctgggcg atgcaaaaga agtgatggat
     1681 gcgtctggtc tggtggtttc tccaggcatg gttgatgcgc acacccatat ttctgagccg
     1741 ggtcgtagcc actgggaagg ttatgaaact ggtactcgcg cagcggcaaa aggtggtatc
     1801 accaccatga tcgaaatgcc gctcaaccag ctgccagcaa cggttgaccg cgcttcaatt
     1861 gaactgaagt tcgatgccgc taaaggcaag ctgactatcg atgcggcaca actcggtggc
     1921 ctggtgtctt acaacatcga ccgtctgcat gagctggatg aagtgggcgt tgtcggcttc
     1981 aaatgcttcg ttgcgacctg tggcgatcgc ggtatcgaca acgacttccg tgatgtaaac
     2041 gactggcagt tcttcaaagg tgcgcagaag ctgggcgaac tggggcagcc ggtgctggtg
     2101 cactgcgaaa acgcgctgat ctgtgacgaa ctgggcgaag aagcgaagcg tgaaggtcgc
     2161 gtaactgctc atgactatgt ggcttcgcgt ccggtattta ccgaagtgga agcgattcgc
     2221 cgcgtgctgt atctggcgaa agttgccggt tgccgtctgc acgtttgcca tatcagcagc
     2281 ccggaaggcg ttgaagaagt gactcgtgca cgtcaggaag gtcaggacgt tacttgtgaa
     2341 tcctgcccgc attactttgt acttgatacc gatcagttcg aagaaatcgg tactctggcg
     2401 aagtgttcac cgccgatccg cgatctggaa aaccagaaag gcatgtggga aaaactgttt
     2461 aacggtgaaa tcgactgcct ggtttccgac cactctccat gtccgccgga aatgaaagcc
     2521 ggcaatatca tgaaagcatg gggtggtatc gccggtctgc aaagctgcat ggacgtgatg
     2581 ttcgatgaag cggtacagaa acgcggtatg tctctgccga tgttcggcaa attaatggcg
     2641 actaacgcag cagatatttt cggtctgcag caaaaaggcc gtatcgcccc aggaaaagat
     2701 gccgacttcg tcttcattca gccgaatagc agctatgttc ttaccaatga cgatctggaa
     2761 tatcgccaca aagtcagccc gtatgttggc cgtaccattg gcgcgcgtat cacgaaaacc
     2821 atcttacgtg gtgatgtgat ttacgacatc gaacagggct tccctgttgc gccgaaaggt
     2881 caatttatcc ttaaacatca gcagtaatct ggcccctgca atgcccgtcc ttgcggcggg
     2941 cattctccgg ttaaggtgtt tttatgttca attttgcagt cagccgcgaa agcctgttat
     3001 caggatttca gtggtttttc tttatttttt gcaacacggt tgtggttcct cctacgctac
     3061 tttctgcttt tcagttgccg caaagtagcc tgcttacgct cacgcaatat gcttttcttg
     3121 ctaccgcact ggcctgcttc gctcaggcgt tctgcggtca tcgtcgcgct attatggagg
     3181 ggccgggcgg cctgtggtgg ggaaccatcc tgactatcac ccttggcgaa gcatcgcgcg
     3241 ggacaccgat caacgatatc gctaccagtc tggcggtggg aattgcgctc tccggcgtgc
     3301 tgacgatgtt gattggtttt agcggattag gccatcgcct ggcacggtta tttacgccgt
     3361 cggtgatggt cttgtttatg ttgatgctgg gcgcgcagct gaccactatc tttttcaaag
     3421 gtatgctcgg gctgccgttt ggcatagccg acccgaattt taaaattcag ttaccgccgt
     3481 tcgcgctttc ggtcgcggtg atgtgcctgg tactggcgat gattatcttt ctgccgcaac
     3541 gttttgcccg ttatggcctg ctggtcggta ccataaccgg ctggttgttg tggtactttt
     3601 gctttccttc ttcgcattcg ctctccggtg agttgcactg gcagtggttc ccgctcggca
     3661 gtggcggtgc tttgtcgccg gggattattc tgacggcggt gattacaggt ctggtaaata
     3721 tcagcaatac ctacggtgcg attcgtggca cggatgtttt ttatccgcag cagggcgcgg
     3781 ggaatacacg ttatcgtcgc agctttgtgg cgaccggatt tatgacactg ataaccgtgc
     3841 cgctggcggt aattccattt tcaccgtttg tttcatccat tggtttatta acccagactg
     3901 gcgattacac gcggcgttcg tttatttatg gcagcgttat ttgcctgctg gtggcactgg
     3961 ttccggcact cacgcgactg ttttgcagta tccccttacc gatgagtagc gcggtcatgc
     4021 tggtttctta tctgccttta ctcttttccg cgctggtgtt tagccagcaa atcacgttta
     4081 ccgctcgcaa tatttatcga ctcgcattgc cgttatttgt cggcatattt ttaatggcat
     4141 taccgcctgt gtatctgcaa gaccttccat taacgcttcg tcctctgctc agtaacggct
     4201 tactggtcgg aattttactg gctgttctta tggataatct tattccgtgg gaacgcatcg
     4261 aataatttgt tgaaaaagga ttgataatga agattgtcat tgcgccagac tcgtttaaag
     4321 agagcttaag tgcagaaaaa tgttgtcagg caattaaagc cgggttttcg accctctttc
     4381 ccgatgcgca ctatatctgt ttaccgatag cggatggcgg cgaagggaca gtggatgcga
     4441 tggtcgccgc gacgggcggc aacatcgtga cgcttgaagt ctgcgggccg atgggcgaaa
     4501 aagtgaatgc tttttatggc attaccggcg acgggaaaac ggcggtgatt gagatggctg
     4561 cggcaagcgg cctgatgctg gtcgcgcctg aaaagcgtaa tccgttgctg gcctccagtt
     4621 ttggtacggg ggagttaatt cgccatgcgc tggataacgg cattcgccat attattctcg
     4681 gcattggtgg tagcgcgacg gttgacggcg gtatgggcat ggcgcaggcg ctcggtgtgc
     4741 gtttccttga tgcctacggt caggtgctgg cggctaacgg cggcaattta gcacgcgtgg
     4801 caagtattga gatggatgaa tgcgatccgc gtctggcgaa ctgccatatt gaagtcgcat
     4861 gtgatgttaa taatccgctg gtaggggcac gcggcgcggc ggcggtgttc ggcccgcaaa
     4921 aaggggcaac gccggaaatg gtcgaagagc tggagcaggg gctgcaaaat tacgcccgtg
     4981 ttttacaaca gcaaactgaa atcaacgtct gccagatggc gggtggtggc gcggcgggcg
     5041 gtatgggcat tgcggcggcg gtattcctca atgcggatat taaaccgggt attgagattg
     5101 tgttgaatgc ggtcaatctt gcgcaggcag tgcagggtgc agcactggtg atcaccgggg
     5161 aagggcgcat cgactcgcaa acggcaggcg gtaaagcgcc gctgggcgtg gcgtcggtgg
     5221 cgaagcagtt taatgtcccg gtgattggga ttgctggcgt attgggtgat ggcgtggaag
     5281 tggtgcacca gtacggcatt gatgcggtat tcagcatttt gccacgtctg gctcctttag
     5341 ccgaagtgct cgccagcggt gaaaccaatc tcttcaacag tgcgcgaaat attgcctgcg
     5401 ccattaaaat aggtcaggga attaaaaact gactattacc tttaaagcgg atgcgattta
     5461 tatcgcatct ttttttacct gaattgacta caaaaaaagc cacggaataa accgtggcaa
     5521 aatccaacat agctaaaaat aatcaggcga gtggtatgac ttaaatctct acgtcgcggt
     5581 tgcaatcttt cgagtaaata tagctgaacg cttcaccacg ccctacgcca taaccagcct
     5641 gtaaagaata agcgcccata aagatgtaat cgcctttttt caccgggatc cagttattgt
     5701 cgaggttata aaccccctga ccggaaagaa tataggcacc gtgttcctga acgtgggttt
     5761 cgatataacc gtggctggca cctggtgcaa aagagaggat atgcatgttc atatcaaaac
     5821 ctaactcttt gggcagaaaa tccagcagaa taacatcgtc catgccttca taatgaatgc
     5881 gttccagttc gctggcattg ccagaaacca gccacggcgc atgaccttcg accggaatat
     5941 agcgacgctt atataaaaag atttggctgt cttcggcctg ggcgttaaca aacgtcatta
     6001 aggagcctgg cgggcaataa agatagccac cttcacttaa ggtaaatgtt ttcccttcgg
     6061 ctttggcagt gatatttcca gagatcacat acaggaacgt ttcaattcct tcaccaccga
     6121 agccctgttg gttgccgccg ttttgatgta gtgtgaccag ataatcaaca aaagaggccc
     6181 ccagctttgg cgtggagagg attgtcgcgt cacaattttc aaagcccgga ataatatttt
     6241 ttaccagacc gtccggggtt agcagcgcga aattaccgtg tttcacaatc gcacggttag
     6301 ccagtaaatc atcgcggtaa ccggtgacgt tatttaaata tcccatttat aactccttat
     6361 ttctgccagg caagttgata aagcatgagt gccaacgttt tgaccccttc ggcaaggtcg
     6421 gtaatattgg tgcgttccgc cgggttatgg ctgatcccgt tgatgctggg aatgaaaatc
     6481 atgcaggtcg gcacgcgagg cgcgaaaatt tgtgcgtcgt gcccggcacc actgtgcatt
     6541 acccggtaat tcagtttttc gctttcacac aattctgtca gggtggcgac aagctccttg
     6601 ttcatcggca cgggttcttc gtccatccat aaatcgatat caataccaat gtccatttca
     6661 tcgcaaatcg cccgcatgtc gttttctaac tgttgggtaa aatcgcgcaa cacggcagtg
     6721 tcggtatgac gacaatcaat agtgaacgtg gttttacccg gcactacatt caccgtattc
     6781 gggcgcggct ccaccttgcc aaaggtcagc accagcggat cgcccatctt tttcgctttc
     6841 tcaactgact gatggcaaat gcgactgaaa gcgtaaaccg tatcacgacg ataacccatc
     6901 ggcgtggtgc ctgcatggtt tgattcgccg ttcagcgtca ccgtatagcg acgttgtccg
     6961 acaattgcat tcaccacgcc aattgactga ccattacttt ccagcacaca accctgttcg
     7021 atatgcagtt cgacaaaggc tttaatatcc tgacgcggag ttagtggggc gttcggcaga
     7081 gtaaatccgc aagccttcat tgcatcgaca aaactatttc ctttggcatc acagatattc
     7141 cgcacgtcgt caggattcgc cagcccaaag atatttttac tgccccagaa gacatacggg
     7201 aagcggctgc cttcttcttc cgccattgcc accacttcga ccgttcgcag cggcgcgccg
     7261 tattgcgttt tcagccagtc aatcgccagc cacgccgcca gtgcgccgaa ttgtccgtcg
     7321 aggttaccgc cgttaaccac ggtatcaata tgcgaaccgc tcagaatcac ttcctgaggg
     7381 tattcgctgc cgttcaggcg gccgtataaa ttccccactt catcgaaacg tgtttccagc
     7441 ccacttgctg ccattctttt tttaaattgc tgctgggttt ccagccactc cggcgaataa
     7501 agtaaacggg tcattccacc cgttgggtca gcaccaaaag aggaaagcca gggcagcgtt
     7561 tcttctatgg cttgacggaa atgtgtaatc ataagaaagt cctgtctcaa caattattgc
     7621 gcaaagggat ttttcgtttc gtatgacgtg ttataaagcg cgtcggaaat taaatactgg
     7681 taaatatcat caacaatttc gatgccttcg acggcggttt tgcgttgttt aatatcctga
     7741 tcctgtccgg gataataaac ctggttaaaa ccgggcgcgg gggtaatggc atttaattcg
     7801 cgcatggtct ggctaagatg ttgacggaat aattcgctgg aggagaaaaa gttcggatta
     7861 ataactacat gtaattgccc caaattacgt ccggcgtgta aatcgtcata catcgaactg
     7921 acctgacgcc cgaacggtaa gccgagtaag acgcctgaga ggacgtcgat catcatcatc
     7981 aggccataac ctttcggtcc ggcagccggg agcagggcgt taaccgcgaa gggatcggtt
     8041 gttggtgcac cgtttttatc gaccgcccag gtatccggga tagacatatt acgcgagcgg
     8101 gcgtcgagca cttttcccca tgcctgtacg gtagtcgcca tatcaaaggt aagaatctcg
     8161 tcgccttttc ccggcgcggc aaaggccagt gggttagtgc cgtagtaaat ttccgcgccg
     8221 ccaaacggca ccaccattgg atcggactgg cacatcgaaa tgccaatcaa tccggcgcgg
     8281 gctgcctgct gcacaaaata agagattgcg ccgctgtgac ccatccggct gataccgacc
     8341 actgcaacgc cattttgctg ggcagttttg atggcatgtt ccatgcccat tttcgccgcg
     8401 acctgtccgg cggcattgtc ggcatgcaaa attgctgaac atggcccggt ttcttcaaga
     8461 cgaaactccg gttcgcggtt ggtgccgcct tttgaaatgc gttctgcgta gtattcaacg
     8521 cgcaccgcgc catgagagtg gatccctctg gcatcggcgt aaaccaatac ttcagccacg
     8581 gttgcagcgt gctcacgttt taacccagcc tggcagagtt tattctcgat tagctggtgg
     8641 agtgtttccc gactgatttt catctgtctt cctttttaac gacggtgtga agcatgactg
     8701 caattaacat acagggaaaa tatctggatt atgtgatcca gacaggcaaa aaaatatagt
     8761 tagaatttat ttgataatcc gctcgctttt aacctggttt ttaaaacaac tatgcttatt
     8821 aaaaaataac gcgtaatagt ctggcggtta tttgaattct tttgttaata atccctgtgt
     8881 gatattcatc accttattta ctcgttgtca tcgataccgt aatcgccaca ttaacactgc
     8941 tcgtgcaatt gccatgggtg caatttttaa ggagttgtta tgatccacgc ctttattcaa
     9001 aaagggtgtt ttcaggattc ggtcagttta atgattattt cacgaaaact cagcgaatca
     9061 gaaaatgttg atgatgtttc cgtaatgatg ggtacgcccg ccaataaagc gttattagat
     9121 accacaggtt tctggcatga cgattttaat aacgccacgc cgaacgatat ttgcgtggca
     9181 attcgtagcg aagcggcgga tgcggggatc gcgcaggcga ttatgcagca gcttgaagag
     9241 gcgctaaaac aactggcgca ggggtcaggc agcagccagg cgttgacgca ggtgcgtcgc
     9301 tgggacagtg cctgtcagaa attacccgac gccagtctgg cgctgatttc agtggctggc
     9361 gagtatgcgg cggaggttgc gaaccaggcg ctggatcgca acctcaacgt gatgatgttc
     9421 tccgataacg tcacgctgga agatgaaatc cagctcaaaa cccgcgcacg cgataaaggc
     9481 ttgctggtga tggggccaga ctgcggtacg tcgatgattg ccgccacgcc gctggctttt
     9541 gctaacgtga tgccggaagg caacattggc gtcattggcg cttccggtac cgggattcag
     9601 gaactgtgct cgcagattgc gcttgcaggg gagggaatta cccacgcgat tggtcttggc
     9661 gggcgcgacc tcagccgtga agtgggcggc atcagtgcgc taacggcgct ggaaatgtta
     9721 tgcaccgatg cgaaaagcga agtgctggca tttgtttcaa aaccacctgc cgaagttgtg
     9781 cgtctgaaaa ttgttaatgc catgaaagca accggcaaac cgacggtggc gctgttttta
     9841 ggttataccc cggcggtggc ccgcgacgag aatgtctggt ttgcctcctc gcttgatgag
     9901 gccgcacgcc tggcttgcct gctttcacgc gtcacggcgc gacgtaacgc aatagcacct
     9961 gtcagcagcg gatttatttg cggtttgtat accggcggta cgctggctgc tgaagcggcg
    10021 ggattacttg ccggacacct tggcgtggaa gccgacgata cccatcaaca tggcatgatg
    10081 ctcgacgccg acggacatca gatcctcgac ctgggcgatg atttttacac cgtcgggcgt
    10141 ccccatccga tgatcgaccc gaccttacgc aacctgttaa ttgccgatct cggcgctaaa
    10201 ccgcaagtgc gcgtgttgct gcttgatgtc gtgattggct tcggtgcgac tgccgatcct
    10261 gccgcctcgc tggtgagcgc ctggcaaaaa gcctgtgccg cgcgtccaga caatcaacca
    10321 ctgtatgcca ttgccacggt gacaggcacc gaacgtgacc cgcaatgccg ctcgcaacaa
    10381 atcgccacgc tggaagatgc ggggatcgcg gtcgtgagtt cgctgccgga agccaccttg
    10441 ctggcggcag cgttaattca tccgctctcg cctgccacac agcaacacac accgtcatta
    10501 ctggaaaacg tcgccgtgat taacatcgga ttacgcagct ttgcgctggc gctacaaagc
    10561 gccagcaaac cggttgtgca ttaccaatgg tcgccagtcg ccggcggcaa taaaaaactg
    10621 gctcgtttat tagaacgttt gcaataaggg gttcccatgt ttacatcagt ggcgcaagcc
    10681 aatgctgcgg ttatcgaaca aattcgtcgt gctcgtccac actggctgga tgtgcaaccg
    10741 gcttcttcac ttatcagcga actaaacgag ggcaaaacac tgcttcacgc cgggccgcca
    10801 atgcgctggc aggagatgac cggacccatg aaaggggcat gtgtgggcgc atgtctgttt
    10861 gaaggctggg cgaaagatga agcgcaggcg ctggcaatgc tggatcaggg ggaagtgaac
    10921 ttcattcctt gtcaccatgt gaatgccgtc gggccaatgg gcggcattac ttctgccagt
    10981 atgccgatgc tggtggtcga gaacgtgacc gacggcaacc gggcgtactg caacctcaac
    11041 gaaggtatcg gcaaagtgat gcgttttggc gcttacggcg aagatgttct gactcgccat
    11101 cgctggatgc gcgatgtgtt aatgccagta ttaagcgcgg cgctggggcg catggagcgc
    11161 ggtatcgatc tcaccgcgat gatggcgcag ggcattacca tgggcgatga gttccatcaa
    11221 cgcaatattg cttcctcagc actgttaatg cgtgcgctgg ccccacacat tgctcgcctc
    11281 gatcatgata aacagcacat cgcggaagtg atggatttcc tcagcgtgac cgatcagttc
    11341 ttccttaacc tcgcgatggc ttactgcaag gcggcgatgg atgctggtgc gatgatccgc
    11401 gcaggcagca tcgtcacggc tatgacccgc aacggcaata tgttcgggat tcgggtaagc
    11461 gggctgggcg aacgctggtt tactgcgcct gtaaacactc cccaagggct gtttttcacc
    11521 ggcttctcgc aggagcaggc gaacccggat atgggcgata gcgcaattac cgaaaccttt
    11581 ggtattggcg gtgcggcgat gatcgcagcg cctggcgtaa cgcgctttgt cggtgcgggt
    11641 ggcatggaag cggccagagc ggtatctgaa gagatggcgg aaatcttcct tgaacgcaat
    11701 atgcagttgc agatccccgg ctgggatttc cagggcgcgt gcctggggct ggatattcgt
    11761 cgcgtggtag aaaccggcat tacgccgctc atcaataccg gaatcgccca taaagaggcg
    11821 gggatcgggc agattggcgc aggcactgtg cgggcaccgt tggcctgctt tgaacaagcg
    11881 ctggaagcac tggctgaaag catggggata ggttgaggaa cgcgcaatga cgatcatcca
    11941 tcctctgctt gccagccgta gcgcaccgaa ttatcgccag tcctggcggt tagcgggcgt
    12001 gtggcggcgg gcgattaacc tgatgacgga aagcggcgaa ctgttaacgc tgcatcgtca
    12061 gggtagtggt ttcggccccg gaggatgggt gcttcgccgc gcgcaattcg atgcgttatg
    12121 cggtggatta tgcggcaatg aacgaccaca ggttgtggtt caagggattc gcctcgggcg
    12181 tttcacggtt aaacagccac agcgttattg tttgctgcgt attacgccgc ctgcgcatcc
    12241 tcaaccgctt gcagcggcat ggatgcaacg cgcggaggaa accgggcttt tcgggccgct
    12301 ggcgttggcg gcaagcgatc cgctgcctgc tgaattacgc cagtttcgtc actgttttca
    12361 ggccgcgctc aatggcgtta agaccgactg gcggcactgg ctgggtaaag gccccggatt
    12421 aacgccaagt catgatgaca cgctgagcgg aatgctgctg gcggcctggt attatggcgc
    12481 tttagatgcg cgctccggtc gcccgttttt tgcctgttcc gacaatcttc aactcgttac
    12541 cacagcggtg agcgttaatt atttacgtta tgccgcgcaa ggatatttcg cctcgccact
    12601 cctgcacttt gttcatgctc tgagttgccc gaaacgtacc gcagcggcga tcgattcgct
    12661 gctggcgctg gggcatacgt caggggccga tacgctgctg gggttctggc ttggccaaca
    12721 attattacaa ggaaaaccat gaaaacactg gttgtggctc ttgggggcaa cgccttactc
    12781 cagcgcggtg aggcgctgac ggcaaaaaat caatatcgca atattgccag tgctgtgccc
    12841 gcgctggcgc gcctggcccg ttcttatcgt ctggcgattg ttcacggcaa cgggccgcag
    12901 gtggggctgc tggcgttaca gaatctggcg tggaaagagg tagaaccgta tccgctggat
    12961 gtactggtgg cggaaagcca ggggatgatt ggctatatgc tggcgcagag cttgagcgca
    13021 cagccgcaga tgccgcctgt cacgacggtg ctgacgcgca ttgaggtttc gcctgatgat
    13081 ccggcgtttt tgcagccaga gaagtttatt ggtccggttt atcagccaga agaacaagag
    13141 gcactggaag cggcttacgg ctggcagatg aaacgtgatg gtaaatattt acgccgggtg
    13201 gtggcgtctc cgcaaccgcg taaaattctc gacagcgaag ccatcgagtt gttgctcaaa
    13261 gaggggcatg tggtgatttg cagtggcggc ggcggtgtgc ctgtgacgaa agacggggta
    13321 gggagtgaag cagtgattga taaagatctc gccgctgcgt tgctcgccga gcagattaat
    13381 gccgatggac tggtgatcct caccgatgct gatgcggtat atgaaaactg gggaacgccg
    13441 cagcaacgtg ccattcgcca tgccacaccg gatgagttag cgccatttgc caaagccgat
    13501 ggttcgatgg ggccgaaggt aacggcggtg agtggctatg tcagaagccg tggtaaacct
    13561 gcgtggattg gggcgttatc gcggattgaa gagacgctgg cgggcgaagc ggggacctgt
    13621 atttcgctgt agtgatgggc accaggcaat tggcacatct agcctgatgc gatgctggcg
    13681 cgtcttatca ggtctacagg cggtgtcgga acggtaggcc ggataaggcg ttcacgccgc
    13741 atccggcaat cggcacacca tgcctgatgc gatgctggcg catcttatca ggcctacagt
    13801 cggtgttgga acggtaggcc ggataaggcg ttcacgccgc atgcggcaag aaaatgagca
    13861 tcaattaact gaacttgctc tgcgcccaaa tcacgccgct agcatattct ggcggcagca
    13921 gcgggattaa ggcttccagc gtcgcggtca gacgcgatgt gtcgctgtcg gtcaaattta
    13981 aatgccccac tttacgcccc ggacggactt ctttgtcgta ccagtgcaga tgcaccagcg
    14041 gcagtttcag ccagtcataa ttcacatcgc taccaatcag gttgatcatc accgacggac
    14101 tattcaccac cggttgtggt aacggcagat cggtaatcgc ccgcagatgc agctcaaact
    14161 ggctgatgct ggcaccgttt tgcgtccagt gcccactgtt atgcacacgc ggagccagtt
    14221 cgttgatcag cagaccttgt ggggtgacaa aacactccat cgccatcacg cccacatagc
    14281 ccagctcctg cataatcgcc gacagcatct cttcggcctg cgcctgctgc tgcgcgttgg
    14341 cctgcgggaa agcgacgctg gtgcgcaaaa taccgtcctg atgcaggtta tgcgtcagcg
    14401 gataaaacac ggtactacca tcaaagccgc gcgcgccaac cagcgacact tcaccagaga
    14461 agtttatgcc ctgctcgaca atacattcgc cgtagcattc agtcggtaac tgttcggttt
    14521 catcggcgcg taaacgccat tgaccgcgtc cgtcatagcc accagtgcga cgcttaacaa
    14581 tcgccagctc acctaaacgc ttaaacaccg caggccactc gctgcgatcg gcaagtaact
    14641 gccacggtgc ggtcggcagg tggagcttat cgaaaagctg cttctgagtc agacggtcag
    14701 caataatcgg gaacacatcg cggttcacaa aggccggatg gcgcgccagc tcgcgggtta
    14761 atgcggtttc cggccagcgt tcgatctcag cggtaatcac actttgttga aaaggcaccg
    14821 ccgccggttc agcgtccagc ccgactggcc agacagcaat gcctaacggt tcgcctgcct
    14881 gacgcagcat acggcctaac tgcccgttcc cgaggacgca aacctgtttc atgccgcacc
    14941 tcgcgggtcc gggttttcca gcacttcgtc agtctgggct ttgcgccagt cattcagacg
    15001 ctggtgcagt tctttatcat gagtcgcaag aatttgtgct gccagtaacg ccgcgtttgc
    15061 cgcgccagct ttaccaatcg ccagcgtacc caccggaatg ccgcgcggca tttgtacgat
    15121 ggagtagaga ctatcgacac cgctcagtgc ggcgctctgt actggcacgc ccagcactgg
    15181 caccagcgtt ttggcggcaa tcatgccagg caggtgcgct gcgccgcctg cgcccgcaat
    15241 aatcacctga taaccgttct cttcggcgct ttcggcgaag ctgaacagtt tatcgggggt
    15301 gcggtgagca gaaaccactt caacgtggtg cgggacattc aggatttcga agatttcggc
    15361 ggcgaactgc atggtagccc agtcgctttt ggaccccatc acgatggcga cacgcgccgg
    15421 attattgcgg gaagacatgc gtcttaaaac tcctgtggta cacaactctc ggctttagag
    15481 ggcacagaga atagcacgga aagagagcaa ggaaaacggt tgcgtggctg tgaaatcagc
    15541 aaagttgcgg gttttttaaa aaggaaaatg aatcagctca acgtcatccg ccgtgacttt
    15601 taccattgaa ccttcagtat gccaggcacc cagcacgacg cggaaagcag gttgctgatt
    15661 ggcgataagt tcatgtactg ccgggcgatg ggtatgcccg tgaatcagcc attgcacctg
    15721 atgtttttcc atcgcactga ccaccgcgtt ttggttaacg tccatgatcg ccagcgattt
    15781 actgctgttg gcttctttgc tgttcgctcg cattcgcgcg gcaatgcgtt tgcgcacaaa
    15841 caacggcagg gcgaggaata gcgtttgcag ccagggtttg tggactttgg cgcgaaaagc
    15901 ctgataaccg gcgtcatcgg tgcacagcgt gtcgccatgc ataatcaata cccggcgacc
    15961 atacagttcg agcacctttt cttccggcaa taacgtcatg ccgctttcac gggcaaagcg
    16021 tttgccgagc agaaaatcac ggttgccatg aatgaaataa cagggaacac cggaatcgga
    16081 caccgctttg atcgctgccg ccatctggcg atggagtggg ttgggatcgt cgtcgccaat
    16141 ccacgcttca aacagatcgc caagaatata cagcgcgtcg gccttgcggg cttcccccgc
    16201 taaaaaacgc agaaaaccgg cggtgatcgc cggttcttcc gcgcagagat gaagatctgc
    16261 aataaagagt gtcgccacga ttactcgcta acggtcacgc tttcaatgat aacgtcttct
    16321 tttggcacgt cctggtgcat accgctacga ccggttgcca cacctttgat tttgtctacc
    16381 acgtccatgc cttcaaccac ttcagcaaac acgcagtaac cccaaccttg caggctttcg
    16441 ccagagaagt tcaggaagtc gttatcaacc acgttgatga agaactgtgc agttgcagag
    16501 tgcggtgcct gagtacgggc cattgccagt gtaccacggg tatttttcag accgttgttg
    16561 gcttcgtttt tgatcggttc tttggtggct ttttgtttca tgcccggttc aaaaccgccg
    16621 ccctgaatca taaagccgtt gataacacgg tggaaaatgg tgttgttgta aaaaccttcg
    16681 cggcagtagt ccaggaagtt tttaactgtt tcaggtgctt tatcgtcaaa agttttgatg
    16741 acaatatcgc cgtgattggt gtggaaagta accatttttg catcctgttc cgtttgattg
    16801 gtgcttcaac ccggttcggg tcatatatag ggtggtgtta tagcataacc gcacgatcgg
    16861 atcatcacgc aatgtatgct gattcgcgcg ggaaatatgg gtattatacg caactcaatt
    16921 acccacacat gtctaaacgg aatcttcgat gctaaaaatc ttcaatactc tgacacgcca
    16981 aaaagaggaa tttaagccta ttcacgccgg ggaagtcggc atgtacgtgt gtggaatcac
    17041 cgtttacgat ctctgtcata tcggtcacgg gcgtaccttt gttgcttttg acgtggttgc
    17101 gcgctatctg cgtttcctcg gctataagct gaagtatgtg cgcaacatta ccgatatcga
    17161 cgacaaaatc atcaaacgcg ccaatgaaaa tggcgaaagc tttgtagcgc tggtggatcg
    17221 catgatcgcc gaaatgcaca aagattttga tgctttgaat attctgcgcc cggatatgga
    17281 gccgcgcgcg acgcaccata tcgcagaaat tattgaactc actgaacaac tgatcgccaa
    17341 aggtcacgcg tatgtggcgg acaacggcga cgtgatgttc gacgtcccga ccgatccgac
    17401 ctatggcgtg ctgtcgcgtc aggatctcga ccagctgcag gcaggcgcgc gcgttgacgt
    17461 ggtcgacgac aaacgcaacc cgatggactt cgttctgtgg aagatgtcga aagagggcga
    17521 accgagctgg ccgtctccgt ggggcgcggg ccgtcctggc tggcacattg agtgttcggc
    17581 aatgaactgc aaacagttgg gtaaccactt tgatatccac ggcggcggtt ctgacctgat
    17641 gttcccgcac cacgaaaacg aaatcgcgca gtccacctgt gcccatgatg gccagtatgt
    17701 gaactactgg atgcactccg gaatggtgat ggttgaccgc gagaagatgt ccaaatcgct
    17761 gggtaacttc tttaccgtgc gcgatgtgct gaaatactac gacgcggaaa ccgtgcgtta
    17821 cttcctgatg tcgggccact atcgcagcca gctgaactac agcgaagaga acctgaagca
    17881 ggcgcgtgcg gcgctggagc gtctctacac tgcgctgcgc ggcacagata aaactgttgc
    17941 gcctgccggt ggcgaagcgt ttgaagcgcg ctttattgaa gcgatggacg acgatttcaa
    18001 caccccggaa gcctattccg tgctgtttga tatggcccgt gaagtgaacc gtctgaaagc
    18061 agaagatatg gcagcggcga atgcaatggc atctcacctg cgtaaacttt ccgccgtatt
    18121 gggcctgctg gagcaagaac cagaagcgtt cctgcaaagc ggcgcgcagg cagacgacag
    18181 cgaagtggct gagattgaag cgttaattca acagcgtctg gatgcccgta aagcgaaaga
    18241 ctgggcggcg gcagatgcgg cgcgtgatcg tcttaacgag atggggatcg tgctggaaga
    18301 tggcccgcaa gggaccacct ggcgtcgtaa gtaattgcgc tattgccgga tgcgagtttt
    18361 cgcatccggt tatcgcctgc gccaccacaa cattcccatc agtagcatcc ccggcaacca
    18421 cacccacatt aattcagaaa taatcacctg atgcccgtac ggcgtggtgt aacgagacaa
    18481 tgcaaacggc gcgactttaa tcacctgcca gggagcgaaa aagcgttcat ctgaccacgg
    18541 ccacagccag ccaacccctt taccgccagt ggttaccgaa tccagcaagc tgtgcgatag
    18601 caacgagacg gttaaaaaca gccagcagcg aatcagccca gccctgaacc atcgacgtcc
    18661 aatcagcaca cataacagcg ggacaacaaa cgcaaacacc aacgaatggg taaacccgcg
    18721 atgaccaaaa acattgccgt aagcaacgcc aaatttaaat gacaatacgt cggcatcggg
    18781 cagcatcgcc aggacgattc cggcaaataa caggcgcgga gggatgactt ttgaacccaa
    18841 ccctaaacca atgcaaaggg gaacggcggc gtgcgtaata acggttggca tgatgatcgc
    18901 ttcggcaaaa tatcgatgct atcagcatgg atgaacgagg cgtagggggc aacagtctga
    18961 aaagagaacc ggcctgttga tacaggccgg gaaagggatc aggcaacaac ctgtacgctg
    19021 tgacctgcaa aacttactgt ctgcccggcg acaattttgc agcgtttgcg cgtttcaacc
    19081 gcaccgtcga ctttcacctg gccttcggca atcgcgattt tcgcctgcgc gccgctttcg
    19141 ctccagcctt ccagtttcag caagtcgcac agctcaacgt gcggatgttt acctaaagaa
    19201 aatgtcgcca tgttactcac cctgtggatc atgatattca acgcacgcct gtagcgtgtt
    19261 ttcaatcagc gtggcaaccg tcatcgggcc aacgccgccg ggaacaggcg taatgtatga
    19321 ggcgcgttta gccgcgtctt caaacacgac gtcgcccaca actttgccat tttccagacg
    19381 gttgatgccg acatcaatca caattgcgcc ttctttgatc cagtcaccag gaataaagcc
    19441 cggcttgccg acggcaacga tcagtagatc ggcattttct acgtggtgac gcagattttt
    19501 agtgaaacgg tgagtcacgg tggtggtgca acctgccagt agcagttcca tgctcatcgg
    19561 gcggccaacg atattcgatg cgccaatcac cacggcgttg aggccgaagg tatcaatatt
    19621 gtaacgctca agcagcgtga caataccgcg cggggtgcag ggacgcagac gcggcgcgcg
    19681 ctggcacagg cgaccgacgt tataaggatg gaaaccgtct acgtctttgt ccggatgaat
    19741 acgttccagc actttgacgt tatcaatacc cgccggtaac ggcagttgaa ccagaatgcc
    19801 atcgatggtg ttgtcggcat tcagcgcatc gataagctcc aacagctccg cttcgctggt
    19861 ggtttccggg aggtcataag agcgggagac gaacccgact tcttcacaag ccttgcgttt
    19921 gcttgcgaca taaatttgcg atgcagggtt actacccacc agcacaacgg ccagtcctgg
    19981 tgcccgcagt ccggctgcaa tacgcgcctg aactttttga gcaacttcag agcgcacctg
    20041 ctgcgcaatc gttttaccgt caataatctt tgctgccatc agagagagga ttccatctgt
    20101 tacgtaggtc gaaggggatg cgcctatttt gtcagaagcg gggcgcgctg tcaggtttcg
    20161 tttcagattt atcgcgtgaa gcgacctctt gcgaaggtga ggcgcaccgt cgctgagatt
    20221 gaaagcttca tttttcgtcc atgatgacgt tgtaaatctg gaactgattt atttccttgt
    20281 ctaaggatta agataattta agaaatacct gac
//
LOCUS       DADXDL010000093        20036 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.093, whole genome shotgun sequence.
ACCESSION   DADXDL010000093 DADXDL010000000
VERSION     DADXDL010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 20036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20036
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.093"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..2753)
                     /locus_tag="IRB70_003816"
     CDS             complement(<1..2753)
                     /locus_tag="IRB70_003816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HBC0633674.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDRLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRAGEQEQTPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQNCDQSVPDGFGGTEPRITCNAWLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYAGISIGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGQGNPVSVEVQSVTDGVKVKVSRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVAADDGSELLVSTARTAETTYRFRQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIKLTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVETTARYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKS
                     AFVEAVGQPSDDASGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDG"
     gene            complement(2814..3461)
                     /locus_tag="IRB70_003817"
     CDS             complement(2814..3461)
                     /locus_tag="IRB70_003817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HBC0633675.1"
                     /translation="MAATHTLPLASPGMARICLYGDLQRFGRRIDLRVKTGAEAIRAL
                     ATQLPSFRQKLNEGWYQVRISGRDAGENELSARLNEPLANGAVIHVVPRLAGAKSGGV
                     FQAVLGAALIAVAWWNPVGWLGAAAVSGLYAAGASMILGGVAQMLAPKARTPTAASTD
                     NGKQNTYFSSLDNMVAQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            complement(3359..4102)
                     /locus_tag="IRB70_003818"
     CDS             complement(3359..4102)
                     /locus_tag="IRB70_003818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633676.1"
                     /translation="MTETESAILAHARRCAPAESCGFVVRTPEGERYFPCVNISGEPE
                     AYFRMSPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGAIHK
                     FRCVPYLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHREDDWWRHGQNLYLDNLEAT
                     GLYQVPLSAAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWHASAFTGIYNDLAAASTFV"
     gene            complement(4108..4806)
                     /locus_tag="IRB70_003819"
     CDS             complement(4108..4806)
                     /locus_tag="IRB70_003819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HBC0633677.1"
                     /translation="MQDIPQETHHETTRLTQSAQVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQAYPIQGTGFELNGKGSAARPTLTVSNLHGMVTGMAEDLQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSDADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYHGPAVADEYDQPTSDITKDKCSKCLNGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            complement(4816..5145)
                     /locus_tag="IRB70_003820"
     CDS             complement(4816..5145)
                     /locus_tag="IRB70_003820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633678.1"
                     /translation="METFHWKVRPDMNVVSEPKVVTVKLGDGYEQRRAAGLNNQLSTY
                     SVTIRVRKCEHPSLKAFLERHGGVRAFQWTPPYDWKPIRVVCRKWSASVGALWVTITA
                     DFEQVVA"
     gene            complement(5145..8210)
                     /locus_tag="IRB70_003821"
     CDS             complement(5145..8210)
                     /locus_tag="IRB70_003821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBC0633679.1"
                     /translation="MDQIANLVIDLGIDAAEFKNEIPRIKNLLNGAASDAERSSARMQ
                     RFMERQTQAARQTTQAASSAATAASVHAQTVEKNAQAHERMAREVEKTRQRMEALSQK
                     IREEQAQAMALAEAQDKAAAAFYRQIDSVKQASAGLQELQRIQQQIRQARNSGGIGQQ
                     DYLALISEVTAKTRVLTQAEEEATRQKVAFIRQLKEQATRQNLSSSELLRARAAQLGV
                     SSAAEVYIRKMEQAGKATHSLGLKSAAARQEIGVLIGELARGNLGALRGSGITLANRA
                     GWIDTLMSPKGMMLGGVIGGIAAAVYGLGKAWYDGQKEGEEFNRQLSLTGHYAGVTAG
                     QLWTLSRAISGNGITQHAAVGALAQVVGSGAFRGNDISMVARAAAQMERSVGQSVSDT
                     ISQFKRLKDDPVNAAKALDNELHFLTATQLEQIRVLGEQGRSSDAARIAMSALAEETG
                     RRTADIDNNLNALGSTLKYLSDLWSRFWDAAMNIGREDSLDAQIATLQEKVSRAKRLP
                     WTASSSQVEYDQQRLNDLQEKKRQKDLQDAKEQAERNYQEQQKRRNAENAALNRMNET
                     EAARHQREIARINAMQYADQAVRDAAIQRENERYEKALASGKKKTRETRNDEATRLLL
                     QYSQQQAQVEGQIAAARQSAGIATDRMTEAHKQLLALQQRISDLDGKKLTADEKSVLA
                     RKDELIQALTLLDVKQQELQKQTALNDLKKKTIQLTSQLAEEERAQRQQHDQDIATVG
                     MGDQQRQRYQVQLSLRQKYQQQLEQLRRDSEQKGTYNTDDYRKAEQALTESLNRQLNE
                     NRRYWQQLEIAQGNWKNGVLRAFQDFTVDADNTAGTAEQVFSSAFSNMGNGLATFVTT
                     GKLNFKSFTSSVLSDMAKILAQATMMKSIKGIGSVLGFDLSSLSLNANGGIYQSADLS
                     RYSGTVVNRPTFFAFAKGAGVMGEAGPEAILPLRRGADGKLGVVADIGGSGMAMFAPQ
                     YNIEINNDGTNGQIGPAALKVVYDLGKKAAADFMQQQARDGGRLSGAYR"
     gene            complement(8194..8511)
                     /locus_tag="IRB70_003822"
     CDS             complement(8194..8511)
                     /locus_tag="IRB70_003822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HBC0633680.1"
                     /translation="MQFVMRLAREFRRADWRRMLSEMSATELGEWGDYFRMQSFSDVW
                     MDAQFASLKALIVRMVSGSSDAAVADFSLLPEENGIPERTDEELMHLGEGISGGVRYG
                     PDS"
     gene            complement(8520..8906)
                     /locus_tag="IRB70_003823"
     CDS             complement(8520..8906)
                     /locus_tag="IRB70_003823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HBC0633681.1"
                     /translation="MFLKQDTFNYEKQSVVLSELSGLQRIEYLTFVQQRTAKFDAGEG
                     ELPEAERQIAFLRMGMDINAWLVSRSLWNAEQSQDVETLYASVITTWSYDALGAGAEM
                     VLSLSGMGAIDNAGDLEHEVLTPEKS"
     gene            complement(8967..9710)
                     /locus_tag="IRB70_003824"
     CDS             complement(8967..9710)
                     /locus_tag="IRB70_003824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633682.1"
                     /translation="MTTPNPLAKTKGAGTTFWMYTGNGDAFANPLSDTDWLRLAMVKD
                     LQPGEMTADAEDDTYLDDEDADWKTTTQGQKSVGDTSATLAWRPGDSGQKKLVQLFDS
                     GEVCAFRIKYPNGTVDVFRGWLSSLGKTIASKDVMTRTVKISGVGRPYLAEEGTETVS
                     VTGLTVAPASASVKVGATTTLTFTVKPDGASDKAISVHSTDPQTATVTLNGLVATVKG
                     VKQGSVSIVGMTADGNFVAVAAVTVSAAG"
     gene            complement(9721..10122)
                     /locus_tag="IRB70_003825"
     CDS             complement(9721..10122)
                     /locus_tag="IRB70_003825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633683.1"
                     /translation="MNRHTQIRQVVLARLREQCGDSATFFDGLPAFIDAQELPAVAVW
                     LSDAQYTGKMTDEDDWQAVLHIAVFIRAQAPDSELDMWMESTIFPALNDIPALSGLID
                     TLIPLGFNYQRDNEMATWAMAEITYQITYTN"
     gene            complement(10119..10709)
                     /locus_tag="IRB70_003826"
     CDS             complement(10119..10709)
                     /locus_tag="IRB70_003826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633684.1"
                     /translation="MKGLENAIRNLNSLDTRMVPQASAWAINRVAQKAVSVATRQVAG
                     NTVAGDNQVKGIPLKLVRQRVRVFKASPSGKMTARIRVNRGNLPAIKLNTTRRRAGEG
                     LRVGKYFFRGAFVQQLANGRWHVLRRLPEARFATGHDHQGRPRKNRLPVEVVKIPLSG
                     PLTQAFEDARDRIIAAEMPKQLGYALKQQLRLWLTR"
     gene            complement(10721..10996)
                     /locus_tag="IRB70_003827"
     CDS             complement(10721..10996)
                     /locus_tag="IRB70_003827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA breaking-rejoining protein"
                     /protein_id="HBC0633685.1"
                     /translation="MSDPFSRLAARMDAITVRKMGKTASVNDVDMTVIPGETLAELNA
                     LSGPAVSLVVFSSGYRPRRGDRVVYDGQQWTVTRHERFNGKPMIFIE"
     gene            complement(10989..11312)
                     /locus_tag="IRB70_003828"
     CDS             complement(10989..11312)
                     /locus_tag="IRB70_003828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308857.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2190 family protein"
                     /protein_id="HBC0633686.1"
                     /translation="MAKNFVEEGKTVAIVASAAISSGDLVQVGDVFAVALTDIPQGET
                     GDGMTEGVFMLPKLKTDDMKTGKKVYLKSGKVQLTNSGSDPLVGVVWADAGTSAEEVP
                     VKLNV"
     gene            complement(11398..13425)
                     /locus_tag="IRB70_003829"
     CDS             complement(11398..13425)
                     /locus_tag="IRB70_003829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308856.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Clp protease ClpP"
                     /protein_id="HBC0633687.1"
                     /translation="MPQRNDRSRSTPTTSPKNNSWFRMQAGHQSDADIYIYDEIGFWG
                     VTAKQFISDLNALGDITHINLHINSPGGDVFEGIAIFNALKTHGASITVYVDGVAASM
                     ASVIAMVGNPVIMPENSFMMIHKPFGFTGGDAEDMRTYADLLDKVEAVLLPAYAQKTG
                     KTTDEIAAMLADETWMSGAECLAQGFADQVTPAVKAMACIQSKRTEEFKKMPESIRNM
                     ITPPRNSAPRVQDDGPAASRTPVQAAAPVVDENSIRAQVLAEQKARVNGINDLFAMFG
                     GRYQSLQAQCLADPECSLEQAREKLLNEMGRESTPSNKNTPAHIYAGNGNFVGDGIRQ
                     ALMARAGFEKTERDNVYNGMTLREYARMSLTERGIGVSSYNPMQMVGAAFTHSTSDFG
                     NILLDVANKAILQGWEDAPETYEQWTRKGQLSDFKIAHRVGMGGFSALRQVREGAEYK
                     YVTTGDKQATIALATYGELFSITRQAIINDDLNMLTDVPMKLGRAAKSTIADLVYAIL
                     TSNPKISTDNVSLFDKAKHANVLESAAMDVASLDKARQLMRVQKEGERHLNIRPAFVL
                     VPTAMESVANQVIRSSSVKGADINAGIINPVKDFATVIAEPRLDDNSQTTFYLAASKG
                     SDTIEVAYLNGVDTPYIDQMEGFSVDGVTTKVRIDAGVAPVDHRGLVKCTA"
     gene            complement(13370..14878)
                     /locus_tag="IRB70_003830"
     CDS             complement(13370..14878)
                     /locus_tag="IRB70_003830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBC0633688.1"
                     /translation="MAILDDVIGVFSPGWKAARLRSRAVIQAYEAVKTTRTHKARREN
                     RTADQLSQYGAVSLREQARYLDNNHDLVIGVFDKLEERVVGKNGIIVEPHPVLRNGAI
                     ARDLAAEIRTRWSEWSVSPEVTGQFTRPMLERLMLRTWLRDGEVFAQMVSGRINSLTP
                     SAGVHFWLEALEPDFIPMTSDESNRLNQGVFVDDWGRPEKYLVYKSRPVSGRQMETKE
                     VDAERMLHLKFVRRLHQMRGTSLLSGVLIRLSALKEYEDSELTAARIAAALGMYIRKG
                     DGQSYETDGNDSKENERELTIQPGIIYDDLKPGEEIGMVKSDRPNPNLETFRNGQLRA
                     VAAGSRLSFSSTARNYNGTYSAQRQELVESTDGYLILQDWFIGAVTRPMYRAWLKQAV
                     VSGVIRLPRDLDRSSLYTAVYSGPVMPWIDPVKEAEAWKIQIRGGAATESDWVRAGGR
                     NPDDVKRRRKAEIDENRKLDLVFDTDPASDKGGSSAATKRQEPQHTDDQSEE"
     gene            complement(14878..15090)
                     /locus_tag="IRB70_003831"
     CDS             complement(14878..15090)
                     /locus_tag="IRB70_003831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001072975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633689.1"
                     /translation="MNQNDIEAMIQRYTEAEMAVLDGKSVTFNGQQMTMENLSEIRQG
                     RQEWERRLAALITRRRGHPGYRLARF"
     gene            complement(15087..17189)
                     /locus_tag="IRB70_003832"
     CDS             complement(15087..17189)
                     /locus_tag="IRB70_003832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HBC0633690.1"
                     /translation="MLNQETAKAARTDSGYILRAPRRMRVADAVAQYMRVPMGAGNSV
                     PWDPLVAPYVIEPMNCLASREYDAVIFVGPARTGKTIGLIDGWVIYNVICDPADMLII
                     QMTEEKAREHSKKRLARTFRVSPEVVSRLSPNKNDNNVYDRTFLAGNYLKIGWPSVNI
                     MSSSDYKCVALTDYDRFPEDIDGEGDAFSLASKRTTTFMSSGMTLVESSPGRDVKDVK
                     WRRTSPHEAPPTTGILSLYNRGDRRRWYWPCPHCGEYFQPCGDVVAGFRDIADPVLAS
                     EAAYIQCPSCSGRILPEQKRELNGRGVWLRDGESINADGSRYGDPRRSRIASFWMEGP
                     AAAYQTLSQLVYKLLTAEQEYETTGSEETLKTVINTDWGLPYLPRASMEQRKSELLEQ
                     RAEPVPSRSVPDGVNFLVATVDVQAGRHRRFVVQVTGYGSRGERWIIDRYNITQSLRG
                     DSDGESQRIDPASYPEDWDVLLTDVFHKSWPLASDPSQQMRLMAMAVDSGGEDGVTDN
                     AYKFWRRCRRDGLGKRIYLFKGDSIRRAKLITRTFPDNTGRTGRRAQAAGDVPLWLLQ
                     TDALKDRVNNALWRDSPGPGYVHFPDWLGSWFYDELTYEERSSDGKWSKPGRGANEAF
                     DLMVYAEALVILHGYEKIRWPDAPEWASRETWLECVPDSTEPSPSPEPVPTPVKKQKR
                     KKTVTDDVNPWLTSGGWL"
     gene            complement(17189..17683)
                     /locus_tag="IRB70_003833"
     CDS             complement(17189..17683)
                     /locus_tag="IRB70_003833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1441 family protein"
                     /protein_id="HBC0633691.1"
                     /translation="MDRELKNLTLNISQLAALSGVHRQTAAARLQNLPVAGGHESNLK
                     LYRVVDIVSAFLALPPPVAEGEMDAHERKAWYQSERERLKFEQETAQLIPASDVRREF
                     AIWAKAVVQVLETLPDILERDCGLQPAAVSRVQSIIDDLRDQIALRVTEPGADDEEEL
                     QQEE"
     gene            complement(18236..18442)
                     /locus_tag="IRB70_003834"
     CDS             complement(18236..18442)
                     /locus_tag="IRB70_003834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633692.1"
                     /translation="MHKDQYTDAPSQEQVRVKTMLNSTISMGYPDVVIACIEHQVSLE
                     AFRAIEAALVKHDKNTKDYSLVVD"
     gene            complement(18738..18911)
                     /locus_tag="IRB70_003835"
     CDS             complement(18738..18911)
                     /locus_tag="IRB70_003835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416068.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="addiction module toxin, GnsA/GnsB family"
                     /protein_id="HBC0633693.1"
                     /translation="MNIEELKTKTEADISEYITKKIIELKKKTGKEVTSIQFTAREKM
                     TGLESYDIKIDLI"
     gene            complement(19084..19239)
                     /locus_tag="IRB70_003836"
     CDS             complement(19084..19239)
                     /locus_tag="IRB70_003836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416069.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633694.1"
                     /translation="MREYPNGETTHLTVMAAGFPSLTGDHKVIYVAADRHVTSEEILE
                     AAMRLLN"
     gene            complement(19387..19575)
                     /locus_tag="IRB70_003837"
     CDS             complement(19387..19575)
                     /locus_tag="IRB70_003837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBC0633695.1"
                     /translation="MTNHIHFRCPCCHGSQYRTSSFDVSDRNPFGAKCIFCKSMMITF
                     DNISQYLNVSHLSLDLRK"
     gene            complement(19586..19798)
                     /gene="cspI"
                     /locus_tag="IRB70_003838"
     CDS             complement(19586..19798)
                     /gene="cspI"
                     /locus_tag="IRB70_003838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock protein CspI"
                     /protein_id="HBC0633696.1"
                     /translation="MSNKMTGLVKWFNPEKGFGFITPKDGSKDVFVHFSAIQSNDFKT
                     LTENQEVEFGIENGPKGPAAVHVVAL"
BASE COUNT         4584 a         5957 c         4605 g         4890 t
ORIGIN      
        1 ccgtcagggg tgttttcaat accggcacca atacccgcga tataaaggcg tccgtcctgc
       61 atctgctgca gcttcacagc ccacatgctg ttcaggttat tatttgtatc aacctgaacc
      121 ttctgtatct gctggatcgc tgcactctgg tcttccagtt tcttattgac ggtctgcgtg
      181 atttcattac tgacatccgt gatggacgtt ctgatttccg ccaggtcagg cgcaagctga
      241 ccgttatcaa tctgcgtcca caactcctga gccagatggg ttttccctat ctctcctttg
      301 aaaaaatcca gatagccgga tgcatcatca ctcggctggc caacagcctc cacgaatgcc
      361 gatttgccaa cggtgttcac actgcggatg taaaaataat aatcatggcc cggcttgata
      421 ttgatactgg cagctatcca gtacagcgcc gtgccaagat agcgggctgt ggtttcaacc
      481 tgcctgatat ccgcaatccg cttttccgag aaccagaact caaactgtac cgtcggatca
      541 taaaccgcaa gatgcggcgt ggcggttatc tgaaaatagc ccggcgtcag cttaatcctc
      601 gacggtgctg ccggtgcggc aatccggaac gataccgacg ccggatcgcc ctgctgcccc
      661 cacgcattta ccgcccggac tgtcagcctg tagttcccca gcgccagttg cctgaagcgg
      721 tatgtggttt ccgccgtccg ggccgtgctg accagcagct cactgccgtc atccgctgcc
      781 acggtcaggc gaagcaggaa actcacgccc ttcaccacct tcggcgtgtc ccagcgcgcc
      841 agcacctgat attccccgct gtctgcggtg acttcggcgg tcaggtgctg caccgctggc
      901 ggcgtgacac cattcaccgt gccgctctgg tcgccgtcaa agtgcgcccc gttatccacg
      961 atggcctctt tttccggtac atgctgcacg gcggtgatgg catacgtgcc gtcgtcgttc
     1021 tcacggatac tcacgcagcg gaacaggcgc tggcgcagcg tcggcagctt cagcccccac
     1081 acgctgtatt cagcaacgcc gtcaggaaca cggctcactt tcaccttcac gccgtcggtg
     1141 acggactgga cctccacgct gaccggatta ccctgaccgt caacaaggct tatcagcgtg
     1201 gtaccggagg atggcagcgt gatttcacgg tcgagcgtca gcgtccgggt ctggctgttc
     1261 acagccagca cgcgcccgcc gatgctgatc cccgcatagt catcatcgca gatttcaata
     1321 acatcacccg gcacatggcg aagcccttcg gcacccacgc tgaagtccac ggtctgcgtt
     1381 tccagcagtt ctgttttaat cagccacagc ccggcgcggt gtgcctgccc ccggctggta
     1441 cagccaaaag catccatctt cgtgacgtta cgaccgtaac gggcaatggc ctgcgtgtcc
     1501 tccacaagct ctgttgccgt ctcccagccg ttatccgggt caatccagtt cacctcaacg
     1561 gcattatggc ggtctttcag ggcgctgaag ctgtagcgga acggcgcgcc atcatccggc
     1621 atcaccacat tactgcggtt ataggtccac accttatccg acggtcggtc ctgcacgaac
     1681 gtcagcgtct gcccgttcca taccggcata cagcgcatcg ccgagcagaa atcactgaga
     1741 acatcccacg ccttacgctg tgtggtcagc caggcattac aggtgatgcg cggctccgtg
     1801 ccaccaaagc catccggcac cgactggtcg caattctggc cgatgacata cagcgcccat
     1861 ttatccacat ccgccgcacc aagacgtttc cccatgccgt agcgcggatg ggtcagcata
     1921 tcccacagac accaggccat gttgttgctg tatgccggtt taaacgttcc gtcccagata
     1981 ccgctgtatt gccgcgtctg cgggttatag ttcgacggca cctgcagaat gcgcccgcga
     2041 agatgataat tacggctcac ctgctggctg ccgaactgct ccgaatccac ctgcacgccg
     2101 accagtgccg tgttcgggta gcactgtttc acatcgataa tttcggtgta tgacgaccag
     2161 agcgttttgt tctgcagctg gtctgtggtg ctgtccggcg tcatcctgcg catccggata
     2221 ttaaacgggc gcggcggcag gttatccacc accaccgagg ccagatactg tgaagtggtt
     2281 ttacccttaa tggtgatgtc tttttccgtc acccagccac cgttacgttg tatctgaacc
     2341 agcaggcgga cttccgatgg attcctgtcc ccctttgagg tggtttccac cagtgcctgc
     2401 acgccgaaag taaaacgcag acggtcaatg tttgccgacg tgatggtccg ggtgatcgga
     2461 gtgtcatatt tcacttctgt accgagcacc gtctcggagc cggaggattc aaacccctcc
     2521 ggcggtgtct gctcctgctc accggcacgg aacaccaccg tgacgccgga tatattggta
     2581 ttcccctcac tgtccagcac cggcgtactg ttcagcagca cgctttttaa tctatccacc
     2641 ggaccttcaa ccggcccttc gctgatggca tcgatcacac tcagcagctg cgtggacttc
     2701 aggttgtcct tcgcttcgcg cggggtatgc cccttactgc tgcctttacc cattcgtcat
     2761 gctccataaa cgataaaacc gcccggaggc ggtttcacat aaaacatttt gcatcagcga
     2821 ccaatcacca caacctgacc accatcccct tcgtctgccg tgctgatctc ctgagaaacc
     2881 acgcgtgacc ccacgcgcat ttcaccgtac agaaccggca gaacattgcc ctgggcaacc
     2941 atgttatcca gtgacgagaa ataggtgttc tgtttgccgt tatctgtact ggctgccgtg
     3001 ggcgtcctgg ctttcggtgc cagcatctgc gccacaccac ccaggatcat actggcccct
     3061 gctgcataca gacccgatac agccgcggcc cccagccagc caacagggtt ccaccatgcc
     3121 accgcaatca gcgccgcacc cagcaccgcc tgaaacacac cgccactttt ggcacccgcc
     3181 agacgcggaa cgacgtggat cacggcacca tttgccagcg gttcattaag acgggcagat
     3241 aattcatttt cgcctgcatc acgcccggaa atgcgcacct gataccagcc ctcattcagt
     3301 ttctggcgaa acgacggaag ctgtgtggcc agcgcccgga tggcttcagc ccccgttttc
     3361 acacgaaggt cgatgcggcg gccaaatcgt tgtaaatccc cgtaaaggca gatgcgtgcc
     3421 atgcccggtg acgccagagg gagtgtgtgc gtcgctgcca tttgtcggta tacctctctc
     3481 gtttgctcag ttgttcagga atatggtgca gcagctcgcc gtcaccacag taaatggcgg
     3541 catgattcgg caccgatgaa ccaaaacagc acagcagcac atcgcccggc tgcgccgctg
     3601 acaacggcac ctgatacagc cctgtggcct ccagattatc cagatagaga ttctgaccgt
     3661 gacgccacca gtcatcctcg cgatgaaaat ccggcatctc aatccccgcc agatggtaag
     3721 catcccggaa cagcgtgtaa cagtccgtca ccccgtgctc aaagcgccgc ccggtgagat
     3781 acggcacaca gcggaacttg tgaatcgccc cccggcagac cagccaccac ggcaaatcac
     3841 tctgcacctg cagccgccgg tcagcctcac tcagccaggg cagaccaccg ggatgactgt
     3901 ggaccagtgc cacaatctca ccctgcatct ctgcctgcag ccagtcctcc ggcgacatcc
     3961 ggaaatacgc ctccggctca ccggagatat tcacgcaggg aaaatatctt tccccttccg
     4021 gcgttctcac cacgaagccg cacgactccg ctggcgcaca tcgccgggcg tgcgccagaa
     4081 tcgctgattc tgtctctgtc atgggattta ctgcgaaagt ttgttaatgg aaaggaagcc
     4141 gccaaagttg ccgacgttat tgcgaaactt acagccattc aggcatttgc tgcatttatc
     4201 cttcgtgata tcggacgtcg gctgatcata ttcatccgcg acagccggac cgtgataacc
     4261 gcactcatca ccgcgatagg tccaggtgca ggtattagcc agcatgatgc gccccggaaa
     4321 aacggcacca tccgtttccg tcggtgtgga cagtacaaag gaggcactca ccgcactcag
     4381 ttcgctgcac tgctcgatgc gccagcggct gatcacctcc tgctccggat cggcgtcgct
     4441 gtttccgttg acgaagttca ccgcatccag aaaacgggcg taaaccttac gcctgaccac
     4501 cgttccgccg accagactct gcaggtcttc cgccatcccg gtgaccatgc cgtgcaggtt
     4561 agagaccgtc agtgtcggac gggcagcact gcccttaccg ttcagttcaa atcccgtccc
     4621 ctgaatgggg tatgcctgat actgccgccc ctgccaggtg accggctcac ctttttcgtt
     4681 ctgctcatta cagaaaaaat aacgttcacc accgacctct gtcagatcga tttcccagag
     4741 caccacctgg gctgactgag tgaggcgtgt cgtctcatga tgtgtttcct gtggaatatc
     4801 ctgcatcagg gcctcctatg ccacgacctg ttcaaaatct gccgttatgg ttacccacag
     4861 cgcccccacg cttgccgacc atttacgaca aaccaccctg atcggcttcc agtcataagg
     4921 tggcgtccac tgaaatgcgc ggacgccacc gtgccgttcc agaaaggctt tcaaagatgg
     4981 gtgttcacat ttacgaacac gtatcgtcac gctgtaagtc gacaactggt tattcagtcc
     5041 cgccgcacga cgctgttcat aaccatcgcc cagcttcact gtcaccactt tcggctctga
     5101 taccacattc atatccgggc gcactttcca gtgaaacgtc tccattaccg atatgctcca
     5161 cttaaccgac caccatcacg ggcctgctgt tgcataaagt ccgctgccgc ttttttccca
     5221 aggtcataaa ccaccttcag ggcagccgga cctatctgcc cgttcgtgcc atcgttattg
     5281 atctcgatgt tgtactgcgg ggcaaacatc gccatacctg aaccaccaat atccgccaca
     5341 acccccagct taccgtcagc accacgacgc agtggcagaa tggcttcagg tccagcttcc
     5401 cccatcacac ccgcgccttt tgcaaaagca aaaaacgtcg gacggttaac caccgtgcca
     5461 ctgtaacgac tcaaatcagc agactgataa atccccccat tggcattcag ggaaaggctg
     5521 ctgagatcaa atcccagtac actgccaatc ccttttatcg atttcatcat ggttgcctgc
     5581 gccaggattt tcgccatatc tgacagcaca gaagaggtga aggatttgaa attgagtttg
     5641 ccggtagtga caaaagttgc caggccattt cccatgttgc tgaaggctga cgagaacacc
     5701 tgttctgctg ttcctgccgt attatctgca tccacggtaa aatcctgaaa tgcacgcagg
     5761 actccgtttt tccagttacc ctgagcaatt tcaagctgtt gccagtaacg gcgattctca
     5821 ttcagttgtc ggttcaggct ctccgtcagc gcctgctcgg cctttctgta gtcatccgtg
     5881 ttatatgtcc ctttctgctc actatcccgc ctcaactgct ccagctgttg ctggtatttc
     5941 tggcgaagac tcagttgtac ctgatatcgc tgccgctgct gatcacccat acccaccgtg
     6001 gcgatatcct ggtcatgttg ctgacgctga gcgcgctctt cttcagccag ttgactggtc
     6061 agctgaattg tttttttctt cagatcgttg agtgccgtct gtttctgaag ctcctgctgt
     6121 tttacatcca gcagcgtcag tgcctgaatc agttcatctt tacgggccag cacactcttt
     6181 tcatctgccg tcagtttttt cccgtccaga tcgctgatgc gctgctgcag agccagaagc
     6241 tgtttatgcg cttctgtcat cctgtcagtg gcaatgcctg ctgactgtct tgcagcagca
     6301 atctgtcctt ccacctgtgc ctgttgctgg ctgtactgca gcaataaccg ggtggcctca
     6361 tcattacggg tttcgcgtgt ttttttctta ccggatgcca gggctttctc gtaacgttca
     6421 ttttcacgtt gtatcgccgc atccctgaca gcctgatcgg cgtactgcat ggcattaata
     6481 cgcgcaattt cacgctgatg tcgtgcagct tccgtttcat tcatccgatt cagtgcagca
     6541 ttttcagcat tacggcgttt ctgttgctcc tgataattcc gctctgcctg ctcttttgca
     6601 tcctgcaaat ccttctggcg ttttttctcc tgaagatcgt taagacgctg ctgatcgtat
     6661 tcaacctgag aagatgatgc cgtccagggg agtcttttcg cccgcgacac tttctcctgc
     6721 aaagtggcaa tctgcgcatc cagcgaatct tcacgaccaa tattcatggc cgcatcccag
     6781 aaacgactcc ataaatcaga cagatacttc agcgtactgc ccagcgcatt gaggttatta
     6841 tcaatatccg cagtacgtcg accggtttcc tctgccagtg cagacatggc tatccgtgcc
     6901 gcatcactgg accgcccctg ttccccaagg acgcgtatct gctcaagctg agtggcagta
     6961 agaaaatgca gctcattgtc cagagccttc gcggcattta caggatcatc cttcagccgc
     7021 ttaaactgac ttatggtatc gctgaccgac tggccaaccg atcgctccat ctgtgcggca
     7081 gctctcgcca ccatactgat atcgtttcca cgaaatgcac cactccccac cacctgagcc
     7141 agcgcaccga ctgcagcatg ttgcgtgata ccattcccgg aaatagcacg actgagcgtc
     7201 cacagctgcc cggcagtgac tccggcataa tgccccgtca gcgacagctg gcggttaaat
     7261 tcttccccct ccttctgacc gtcataccag gctttaccca gaccatagac agccgcggca
     7321 ataccaccaa taaccccgcc aagcatcatg cctttcggtg acatcagtgt gtctatccac
     7381 ccggcacggt tagccagcgt tattccggat cccctcagcg cacctaaatt tccgcgggcc
     7441 agttcaccta tcagaacgcc tatctcctga cgggccgctg cacttttcag acccagcgaa
     7501 tgcgtggctt ttcctgcctg ctccattttg cggatataca cttctgcagc actgcttacc
     7561 cccagctggg cagccctggc acgaagcaac tcagaagaag aaagattctg gcgggttgcc
     7621 tgctctttaa gctgacggat aaacgccact ttctgtcggg tagcctcttc ctcagcctgt
     7681 gtaagaacac gggttttcgc cgtaacctca gaaatcagcg ccagataatc ctgctgacca
     7741 atcccgccac tgtttctggc ctgtcggatc tgctgctgaa tacgctgtaa ttcctgcagc
     7801 cccgcactgg cctgtttcac actgtcaatc tgacgataaa acgcggcagc cgctttatcc
     7861 tgagcctccg ccagagccat ggcctgcgcc tgttcctcgc gtattttctg gctcagtgcc
     7921 tccatacgct ggcgggtttt ctccacctcg cgggccatgc gttcatgagc ctgtgcgttc
     7981 ttctccaccg tctgcgcatg gacggatgcg gctgttgcag ccgaagacgc cgcctgcgtt
     8041 gtctgccggg cggcctgagt ctgacgctcc ataaaacgct gcatacgggc agaagaccgt
     8101 tctgcatcgc tggctgcacc attcagaagg tttttgatac ggggaatttc atttttaaac
     8161 tctgccgcat caatccccaa atcaatgacc aggttagcta tctggtccat aacgcacacc
     8221 tccggaaata ccttccccaa gatgcatcag ttcttcgtcc gttcgctccg gtatcccgtt
     8281 ctcttccggt aaaaggctga aatcagccac cgcagcatca ctgctgccgg acaccattct
     8341 cacgatcaat gccttcagcg aggcaaactg cgcatccatc cacacatcac tgaagctctg
     8401 catccggaaa taatcgcccc actcaccaag ctcagtggcc gacatttccg acagcatccg
     8461 ccgccagtct gcccgccgga actcccgggc aagccgcatg acaaactgca tttcccgcgt
     8521 caggactttt ccggcgtcag cacctcatgc tccaaatccc cggcattatc aatggccccc
     8581 ataccgctca gcgacagaac catctccgcc cccgcaccca gggcatcata cgaccatgtt
     8641 gtaataacgg atgcgtaaag cgtctcaaca tcctgagact gttccgcatt ccacagtgag
     8701 cgggaaacca gccaggcatt gatatccatc cccatccgca gaaaagcaat ctgtcgttca
     8761 gcctccggca gttctccctc cccggcatca aactttgccg ttcgctgctg aacaaacgtc
     8821 agatattcaa ttctctgcag cccggacagc tcactgagca ccacggactg tttttcataa
     8881 ttaaacgtgt cctgtttcag aaacatcatg ttctccacct gtaaaaaagc cccgaataac
     8941 cggggcaaat gatgagtatc gtcctgttaa cctgctgcgc tgacagtcac cgcagccaca
     9001 gccacaaaat tcccgtcagc ggtcatgccc acaatgctga cactgccctg cttcacgcct
     9061 ttcaccgtgg ccacaagccc gttcagggtc accgtggcag tctgtggatc tgtcgaatgc
     9121 acactgatcg ctttgtcact ggctccgtca ggttttactg taaaggtcag cgtggtggtt
     9181 gctcccactt ttacactggc agatgccggt gccaccgtca gcccggtaac gctcactgtt
     9241 tcagtgcctt cctctgccag atacggacgc cccacaccgc tgattttcac tgtgcgggtc
     9301 atcacgtctt ttgaggcaat ggttttaccc agtgaactca gccagccacg gaaaacatca
     9361 acagtaccgt tgggatattt gatacgaaac gcgcagactt caccggagtc gaacaactga
     9421 accagttttt tctgcccgct gtcacccgga cgccaggcca gcgtcgccga agtatcacca
     9481 acggatttct gcccctgggt tgtcgttttc cagtctgcat cttcatcatc gagataagtg
     9541 tcatcttctg catcagcggt catttcgcca ggttgcagat ccttcaccat cgcaagacgc
     9601 agccagtcag tgtccgacaa aggattcgca aacgcatcgc cgttgccggt atacatccag
     9661 aacgtcgtcc ccgcaccttt cgtctttgcc agtggatttg gtgtggtcat taccacctcc
     9721 ttaattcgtg tacgtgatct ggtacgtgat ttccgccatc gcccaggtgg ccatctcatt
     9781 atcacgttga tagttaaaac cgagtgggat cagggtgtcg atgagtccgg aaagtgccgg
     9841 tatatcattc agggcaggaa aaatggtgct ctccatccac atatccagct ctgaatccgg
     9901 tgcctgtgcc cggatgaaga cggcaatatg cagaacagcc tgccagtcat cttcatccgt
     9961 catttttccg gtgtactgag catcactcag ccacaccgcc acggcaggca gttcctgcgc
    10021 atcaataaat gccggaagcc cgtcaaaaaa cgtggcgctg tctccacact gttcccgaag
    10081 gcgtgccagt acgacctggc ggatttgtgt atgtcggttc atcgggtcag ccataatctc
    10141 agttgttgtt tcagtgcata ccccagctgt ttcggcattt ccgcagcaat gatgcggtcg
    10201 cgggcatctt caaatgcctg tgtcagcggt ccggacagcg ggattttcac tacctccaca
    10261 ggaagacgat tttttcttgg cctgccctga tggtcatgcc ctgttgcaaa acgcgcttca
    10321 ggaagacgcc taagaacatg ccagcggcca ttcgccagtt gctgaacaaa tgccccccgg
    10381 aaaaagtatt ttcccactct cagtccttca ccagcacgcc gccgtgttgt gttcagtttg
    10441 atggcgggca gattgccccg gttaacgcgg atcctggccg tcatttttcc tgacggactg
    10501 gctttaaaca cccggacacg ctgacgtacc agtttcaggg ggatcccttt cacctggtta
    10561 tctcccgcaa cggtattccc ggcaacctgc cgggtggcaa ccgagaccgc tttctgtgcc
    10621 acacggttta tcgcccatgc gctggcctgt ggcaccatac gggtatcaag gctgttcaga
    10681 ttgcggatgg cattctcaag ccccttcatc ccacacctct ttactcaata aagatcattg
    10741 gcttaccgtt aaagcgttca tgccgtgtga ccgtccattg ttgtccgtca taaacaacgc
    10801 gatccccgcg ccgtgggcgg tatcccgaag aaaacaccac cagagagacc gcaggtccgg
    10861 acagagcatt cagctctgcc agtgtttctc ccgggatcac agtcatatcg acatcattaa
    10921 ccgaggctgt ctttcccatc tttctgaccg tgatcgcatc catacgcgct gccagccggg
    10981 aaaagggatc agacattgag ttttaccggc acttcttctg cactggttcc ggcatctgcc
    11041 cagacaaccc cgaccagcgg atcagagcca ctgttagtca gctgaacttt tccggacttc
    11101 agataaacct tcttacccgt tttcatatca tccgttttca gcttaggcag cataaacaca
    11161 ccttcggtca tgccgtcgcc tgtttcaccc tgtggaatat cggtcagcgc caccgcaaaa
    11221 acatcaccca cctgcaccag atctccgctg ctgatggctg cactggcaac aatcgccacc
    11281 gtttttcctt cttctacaaa attctttgcc ataactgtct ccgcactgcc ccgttcaggg
    11341 gctgatttca ggtacaaaaa aagcccttac gggcatcaga gttgttgtct gcgacgttta
    11401 cgccgtacat ttcaccagac cgcggtgatc aactggcgcg acaccggcgt caatacgcac
    11461 tttcgttgtc acgccatcca cactgaagcc ctccatctga tcaatatatg gcgtatccac
    11521 accgttgaga taagccactt caatcgtatc ggagcctttt gacgcagcca ggtagaaggt
    11581 ggtctggctg ttatcatcaa gacgaggctc tgcaataacg gtcgcaaaat ctttcaccgg
    11641 gttaataata ccggcgttaa tgtcagcccc cttgacactt gaggagcgaa tgacctggtt
    11701 agcaacagac tccatcgccg tcggtaccag tacgaacgca ggacgaatat tcagatgacg
    11761 ctccccctct ttctgaacgc gcatcaactg gcgggcttta tccagcgatg ccacgtccat
    11821 tgcagcgctc tccagtacgt ttgcatgttt cgctttatcg aacagactta cattatctgt
    11881 ggagattttc gggttagacg tcagaatggc ataaaccaga tcggcaatag tggatttcgc
    11941 cgcacggccc agtttcatcg ggacatcggt cagcatattc agatcatcat tgataatggc
    12001 ctgacgggtg atactgaaca gctcgccata ggtcgccagt gcaatagtgg cctgtttatc
    12061 tccggtggtg acgtatttat attccgcccc ttcacgcacc tgacgcagag cactgaagcc
    12121 ccccataccc acacgatggg caattttaaa atcagacaac tgacctttcc gcgtccactg
    12181 ttcataggtt tcaggagcat cttcccagcc ctgcagaatg gctttgttcg caacatccag
    12241 cagaatatta ccgaagtcag acgtactgtg tgtgaacgcc gcaccgacca tctgcatcgg
    12301 gttataactg gaaacaccaa taccacgttc agtcagtgac atacgggcat attcacgcag
    12361 ggtcatcccg ttgtagacat tatcacgttc agttttttca aacccggcgc gcgccatcag
    12421 cgcctggcgg atcccgtccc ccacaaaatt accgttaccg gcataaatat gagccggggt
    12481 atttttattg gatggcgtgg actcgcgccc catctcgttc aacagctttt cgcgggcctg
    12541 ctccagcgaa cattcaggat cggcaagaca ctgagcctgc aacgactgat aacgcccgcc
    12601 aaacatggca aacagatcat taataccgtt tacacgcgct ttttgctctg ccaggacctg
    12661 cgcacggatg ctgttttcat ccaccacggg tgctgctgcc tgcactggcg tccgggaggc
    12721 tgcaggtcca tcatcctgta cgcgtggagc actgttgcgt ggcggagtaa tcatatttcg
    12781 aatggattcc ggcatctttt taaattcctc tgtacgtttt gactgaatac atgccattgc
    12841 cttaacggct ggtgtcacct gatcagcaaa tccctgtgcc agacattcgg caccggacat
    12901 ccaggtctca tccgccagca tggcagcaat ttcatcggtg gttttcccgg ttttctgtgc
    12961 ataagcgggt aacagaaccg cctcaacttt atcgagcagg tcggcatagg tgcgcatgtc
    13021 ctccgcatca ccgcccgtaa agccaaatgg tttatgaatc atcatgaagg agttttccgg
    13081 cataatgacc gggtttccca ccatcgcaat gaccgacgcc attgacgccg ccacaccgtc
    13141 gacataaacg gtaatggacg caccatgtgt tttcagtgca ttaaaaatgg cgatgccttc
    13201 aaagacatcg ccacccggtg aattaatatg gagattaatg tgggtgatat cgcccagtgc
    13261 attcagatca ctgataaact gcttcgccgt aacaccccag aaaccaatct cgtcataaat
    13321 ataaatatcc gcgtcactct ggtgacctgc ctgcatcctg aaccaagaat tattcttcgg
    13381 actggtcgtc ggtgtgctgc ggctcctgtc gtttcgttgc ggcactgctg cctcctttat
    13441 cactggccgg atcggtatca aataccagat ccagcttgcg gttttcatca atttcggcct
    13501 tgcgccgacg tttgacatca tctggattac gaccacctgc acgtacccag tctgattctg
    13561 tcgccgctcc accacgaatc tgaattttcc aggcctcagc ctccttaaca gggtcaatcc
    13621 acggcatcac cggtccggaa tacaccgcgg tatacagtga agatcggtcc agatcgcggg
    13681 gtagcctgat aacaccggat accacagcct gtttcagcca ggcacggtac atcgggcggg
    13741 tgacggcacc aataaaccag tcctgcagga tcaggtagcc atcagtagat tcaaccagct
    13801 cctgacgctg ggcgctgtaa gtgccgttat agttgcgcgc tgtactggaa aaactcagac
    13861 gactgcccgc agccacggca cgcaactgac cattacgaaa agtttcaagg ttaggattgg
    13921 ggcgatccga cttcaccatt ccgatttctt cgccgggttt cagatcgtcg taaataatgc
    13981 ctggctgaat ggtaagctcg cgttcattct ccttgctgtc attaccatcc gtttcatagc
    14041 tctgtccgtc gcctttccgg atgtacatcc ccagagcagc ggcgatcctt gctgcagtca
    14101 gctcagaatc ttcatactct ttcagagcac tgaggcggat cagcacaccg gacaacaaag
    14161 acgtcccgcg catctggtgc agacggcgaa caaatttaag atgcagcatt cgctctgcat
    14221 ccacttcttt ggtttccatc tgccgcccgg atacgggacg gcttttatac accagatatt
    14281 tttcgggacg cccccagtca tcaacaaaca cgccctgatt cagcctgttg ctctcatcac
    14341 tggtcatggg aataaagtcc ggctcgagcg cctccagcca gaaatgaaca ccggcagaag
    14401 gcgtcaggct gtttatgcgc ccggaaacca tctgggcaaa cacctcacca tcgcgcagcc
    14461 aggtacgcag catcagacgt tccagcatcg gacgggtaaa ctgcccggtg acctccggac
    14521 tgacagacca ttcactccat cgggtacgta tctccgctgc cagatcacgg gcaatggccc
    14581 cattgcgtaa taccggatgt ggctcgacaa taatcccgtt tttccccacc acccgttctt
    14641 ccagcttgtc aaatacacca atgaccagat cgtggttgtt atcaaggtaa cgagcctgct
    14701 cacgtaacga cacggccccg tactggctta actggtcggc agttcggttc tcccgtcggg
    14761 ctttgtgtgt ccgcgtcgtt tttacggcct cataagcctg gatcaccgca cgggaacgca
    14821 gccttgccgc tttccatcct ggtgaaaaaa cgccaatcac atcatcaaga attgccatca
    14881 gaacctcgcc agccggtacc cgggatgccc ccgtcgtcgt gtaatcagag ccgcaaggcg
    14941 gcgctcccac tcctgccgcc cctgccggat ctcagataag ttttccatgg tcatctgctg
    15001 accattaaaa gtgacggatt ttccgtccag caccgccatt tcagcttccg tataacgctg
    15061 aatcatggct tcaatatcat tctgattcat aaccatcctc cggaagtcag ccaggggtta
    15121 acatcgtcag ttactgtttt cttccgtttt tgttttttaa caggcgtggg taccggttcc
    15181 ggtgagggtg acggttcggt actgtccggg acacactcca gccaggtttc ccggctcgcc
    15241 cactccggtg catccggcca gcggatcttt tcgtatccat gcagaatgac cagagcctcg
    15301 gcatacacca tcaggtcaaa agcttcgttg gcaccgcgac ccggcttact ccatttcccg
    15361 tcactgctcc gctcttcata cgtcagttcg tcgtaaaacc agctccccag ccagtcaggg
    15421 aaatgcacat agccgggacc tggcgagtca cgccataacg cgttattcac ccggtctttc
    15481 agggcatccg tctgaagaag ccagagcggc acatcacctg cggcctgcgc ccgtcggccc
    15541 gttcgtccgg tgttatcagg gaatgtacgg gtgatcagtt ttgctcgccg gatgctgtcg
    15601 cccttaaaca ggtaaatacg tttaccaagg ccatcacgac ggcaacgacg ccagaattta
    15661 taggcattat cagtgacccc gtcttcaccg ccggagtcca ccgccattgc catcagtcgc
    15721 atttgttgag aagggtcgga ggccagcggc cagcttttat gaaaaacatc cgtcagcagg
    15781 acatcccagt cttccggata gctggccgga tcaattcgct ggctctcccc gtcgctgtca
    15841 ccgcgcaatg actgcgtgat gttgtaacga tcaataatcc agcgttcgcc acggctgcca
    15901 tagcccgtta cctgaaccac aaaacggcga tgacgtcccg cctgcacatc cactgtcgcc
    15961 acaaggaaat taacgccatc cggcacactg cgggaaggaa ctggctctgc ccgctgctca
    16021 agcaattcac tttttcgttg ctccatgctg gcgcggggaa gataaggtaa tccccagtcg
    16081 gtattgataa ccgtcttgag tgtctcttca cttccggttg tctcgtattc ctgttctgca
    16141 gtaagcagtt tgtaaacgag ttgcgagagt gtctgataag cagctgccgg accctccatc
    16201 cagaatgacg caatacgtga acgccgggga tcaccataac gactgccatc tgcattgatg
    16261 gattcaccat cccgtaacca gaccccacgt ccgttcagct cgcgtttttg ttcaggcaaa
    16321 atccgtcctg aacaggaagg acactgaata taagccgcct cacttgccag cacaggatcg
    16381 gcaatatcac ggaaaccagc aaccacatcg ccgcagggct gaaaatactc accacagtgt
    16441 ggacagggcc agtaccagcg acggcgatcg ccacggttat agagcgacag gatccccgtg
    16501 gttggtggag cctcatgcgg tgaagtccgt cgccatttca catccttcac atccctgccg
    16561 ggggaactct ccaccagcgt cataccactg gacataaatg tggtggtacg ttttgaggca
    16621 agagagaagg catccccctc accatcaata tcttccggaa aacggtcata atccgtcagc
    16681 gccacgcatt tataatctga tgaagacatg atattgactg acggccagcc gattttcagg
    16741 tagttgccag caaggaatgt tctgtcataa acgttgttgt catttttgtt cggactcagg
    16801 cgactgacca cttccgggct gacgcgaaac gttctggcga gtcgtttttt ggagtgttcg
    16861 cgggcttttt cctccgtcat ctgaatgatc agcatatcag caggatcgca aatcacgttg
    16921 taaatcaccc agccgtcaat caggccgata gtcttgccgg ttcgtgccgg gccaacaaat
    16981 atcactgcgt cgtattcacg cgaggccagg cagttcatag gctcaataac atacggtgcc
    17041 accagcggat cccatgggac tgagttccct gcccccatgg gcacccgcat atactgagca
    17101 acggcatcag caacccgcat tcgtctcggt gcgcgaagga tataacctga atcggttcgt
    17161 gctgcctttg cggtttcctg attcagcatt actcctcctg ctgtaattcc tcctcatcat
    17221 ccgcacctgg ttcagtcacc cgcagggcta tctgatcgcg cagatcatca ataatggact
    17281 gaacacggct cacagcggca ggctgcagac cgcagtcacg ttcaagaata tccggtaatg
    17341 tctccagcac ctgcacgacc gcttttgccc agatggcaaa ctcccgtctg acatcactgg
    17401 ccggaatgag ttgtgccgtt tcctgttcga acttaagacg ctcacgttca gactgatacc
    17461 aggctttgcg ctcatgtgcg tccatttcgc cttctgcaac cggcggtggt aatgccagaa
    17521 atgccgacac aatatcaacc acccgataaa gcttgaggtt gctttcatgc ccccctgcaa
    17581 cgggtagatt ttgcagcctt gccgcagcag tctggcgatg tacacctgac agtgccgcca
    17641 attgactgat attcagcgtc agatttttta actctcgatc catacccgct ccagaatgtt
    17701 ttaaacatgc atcttgcgaa cgactttagg caaacggtgt tagtgatgaa caaaaaacaa
    17761 tcaaaatcga caccacaaaa ataaatatac tgtaatatca atctattaca gtagtggtga
    17821 tgacgaatga aatttcaaaa actagccttt ttccgcgacg ctcccgcccc gtggcaggga
    17881 cccccactgg gaggacccga cagcctgaca accgtgacga gcatctgaaa cagagcgtta
    17941 cataatggca tgggtataat tcagaaggac atcacagcat gcccacacaa attagtgtga
    18001 gtgtcctgtt tcttactacg cgcaggactg acgagcatga ggggaaaata cgcgaaccga
    18061 aatgccttat cttcagaaat gcagccggca tccgaactgg acgatattgt aaattcacct
    18121 aaatacgagg cattgctgta gttgaattgc agtactgtat tagccttaca gtgacagaat
    18181 acgatattga ctctgtcact tgtgaaatgg tcagaatggt tagcagttat ggtgatcagt
    18241 caaccaccag ggaataatcc ttcgtattct tatcgtgctt tactaacgcg gcctcaattg
    18301 ccctgaatgc ttccagagat acttgatgtt ctatacatgc aattacaaca tccgggtaac
    18361 ccatcgaaat ggtgctatta agcatagttt ttacacgaac ctgctcctgg gagggggcat
    18421 cagtgtattg atctttatgc attttgtcgc tccattcgtt tgctcttcac ttgcggctaa
    18481 aaatataacg tcaaatcact cagcatgaaa gagtgaaagt ttcagcgcgt ttcccttaca
    18541 taatctgtcg tttgtattct cttcaggcat accggaaaga ctaggtattg tcacacaacc
    18601 aataccatcg acaatcgaga tttatatcta ttcggtaatg tttaaatata acaaaacccc
    18661 gtaaaaacga ggtttatggg taatttgtat tgttgaatag catctgatga gaaattgatg
    18721 ctaatactat aaacatgcta gattaaatca atcttgatat catagctttc aagaccagtc
    18781 attttttccc gtgcagtaaa ctggatactg gtaacttctt tcccggtctt tttcttaagc
    18841 tcaatgattt tttttgttat atattcagaa atatctgctt ctgtttttgt ttttaactct
    18901 tcaatgttca tcatttcctc ttttagtctg ttatgactgt cctggtacac agtagtgtca
    18961 attatatgga gcaaacgtat aaaagataag atgaaacatc gcaataatca acatacgacg
    19021 gtctaaattt cacacaaaca gataaagatg attatcattt attatcaatg cattagaatc
    19081 aaatcaattc aagagtctca ttgctgcttc cagaatttct tctgaagtta catgtcgatc
    19141 cgctgctaca taaatgactt tatgatctcc ggtcagagat ggaaaccctg cagccattac
    19201 agtgaggtgt gttgtttcgc catttggata ttcacgcatg atggtgttaa ctccggtcat
    19261 cactggcact accattgctg gttcagagtt aaaaaaaact attatttttt tcataatgtt
    19321 accgtaatat gtgagtatcc atcgactaga cactaagcaa aaaagctccc gaaggagcct
    19381 tcattttcac tttcttaaat ctaacgacag atggctaaca tttaagtatt gtgaaatatt
    19441 atcaaatgta atcatcattg atttacaaaa gatacatttt gccccgaaag gatttctgtc
    19501 agaaacatca aaagatgatg ttctatactg agaaccatgg caacacgggc atctaaagtg
    19561 aatatggttt gtaatatttt ctacctcaaa gtgccactac atgaacagct gcagggcctt
    19621 taggtccgtt ctcaatacca aattcgactt cctgattctc agttaacgtt ttgaaatcgt
    19681 tgctctgaat agctgagaaa tgcacaaaca catctttgct accatctttc ggcgtgatga
    19741 aaccaaaacc tttttcaggg ttaaaccatt tcactaaacc agtcattttg ttagacatca
    19801 ttattacctt ttgaagaagt tagcccttgg gcagaatggt ccgaaaaaaa atatcagaga
    19861 gaaaaaccaa caaggaaatc tcaagaggta caaataataa aattataaca atgactgctt
    19921 cagataattt tgtaacaaac cagaacacca ttaacgcatg attaaccaac catagcaagg
    19981 attacttttg taaagaaaaa cacacgaatg aaacaatagc tttatttatt aataaa
//
LOCUS       DADXDL010000094        19802 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.094, whole genome shotgun sequence.
ACCESSION   DADXDL010000094 DADXDL010000000
VERSION     DADXDL010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19802)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19802)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19802
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.094"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            134..862
                     /gene="gadW"
                     /locus_tag="IRB70_003839"
     CDS             134..862
                     /gene="gadW"
                     /locus_tag="IRB70_003839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadW"
                     /protein_id="HBC0633697.1"
                     /translation="MTHVCSVILVRRSFDIHHEQQKISLHNESILLLDKNLADDFAFC
                     SPDTRRLDIDELTVCHYLQNIRQIPRNLGLHSKDRLLINQSPPMPLVTAIFDSFNDSG
                     VNSPILSKMLYLSCLSMFSHKKELIPLLFNSISTVSGKVERLISFDIAKRWYLRDIAE
                     RMYTSESLIKKKLQDENTCFSKILLASRMSMARRLLELRQIPLHTIAEKCGYSSTSYF
                     INTFRQYYGVTPHQFAQHSPGTFS"
     gene            complement(1225..4338)
                     /locus_tag="IRB70_003840"
     CDS             complement(1225..4338)
                     /locus_tag="IRB70_003840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit"
                     /protein_id="HBC0633698.1"
                     /translation="MANYFIDRPVFAWVLAIIMMLAGGLAIMNLPVAQYPQIAPPTIT
                     VSATYPGADAQTVEDSVTQVIEQNMNGLDGLMYMSSTSDAAGNASITLTFETGTSPDI
                     AQVQVQNKLQLAMPSLPEAVQQQGISVDKSSSNILMVAAFISDNGSLNQYDIADYVAS
                     NIKDPLSRTAGVGSVQLFGSEYAMRIWLDPQKLNKYNLVPSDVISQIKVQNNQISGGQ
                     LGGMPQAADQQLNASIIVQTRLQTPEEFGKILLKVQQDGSQVLLRDVARVELGAEDYS
                     TVARYNGKPAAGIAIKLAAGANALDTSRAVKEELNRLSAYFPASLKTVYPYDTTPFIK
                     ISIQEVFKTLVEAIILVFLVMYLFLQNFRATIIPTIAVPVVILGTFAILSAVGFTINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVIAEDKLPPKEATHKSMGQIQRALVGIAVVLS
                     AVFMPMAFMSGATGEIYRQFSITLISSMLLSVFVAMSLTPALCATILKAAPEGGHKPN
                     ALFARFNTLFEKSTQHYTDSTRSLLRCTGRYMVVYLLICAGMAVLFLRTPTSFLPEED
                     QGVFMTTAQLPSGATMVNTTKVLQQVTDYYLTKEKDNVQSVFTVGGFGFSGQGQNNGL
                     AFISLKPWSERVGEENSVTAIIQRAMIALSSINKAVVFPFNLPAVAELGTASGFDMEL
                     LDNGNLGHEKLTQARNELLSLAAQSPNQVIGVRPNGLEDTPMFKVNVNAAKAEAMGVA
                     LSDINQTISTAFGSSYVNDFLNQGRVKKVYVQAGTPFRMLPDNINQWYVRNASGTMAP
                     LSAYSSTEWTYGSPRLERYNGIPSMEILGEAAAGKSTGDAMKFMADLVAKLPAGVGYS
                     WTGLSYQEALSSNQAPALYAISLVVVFLALAALYESWSIPFSVMLVVPLGVVGALMAT
                     DLRGLSNDVYFQVGLLTTIGLSAKNAILIVEFAVEMMQKEGKTPIEAIIEAARMRLRP
                     ILMTSLAFILGVLPLVISHGAGSGAQNAVGTGVMGGMFAATVLAIYFVPVFFVVVEHL
                     FARFKKA"
     gene            complement(4363..5520)
                     /gene="mdtE"
                     /locus_tag="IRB70_003841"
     CDS             complement(4363..5520)
                     /gene="mdtE"
                     /locus_tag="IRB70_003841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtE"
                     /protein_id="HBC0633699.1"
                     /translation="MNRRRKLLIPLLFCGAMLTACDDKSAENAAAMTPEVGVVTLSPG
                     SVNVLSELPGRTVPYEVAEIRPQVGGIIIKRNFIEGDKVNQGDSLYQIDPAPLQAELN
                     SAKGTLAKALSTASNARITFNRQASLLKTNYVSRQDYDTARTQLNEAEANVTVAKAAV
                     EQATINLQYANVTSPITGVSGKSSVTVGALVTANQADSLVTVQRLDPIYVDLTQSVQD
                     FLRMKEEVASGQIKQVQGSTPVQLNLENGKRYSQTGTLKFSDPTVDETTGSVTLRAIF
                     PNPNGDLLPGMYVTALVDEGSRQNVLLVPQEGVTHNAQGKATALILDKDDVVQLREIE
                     ASKAIGDQWVVTSGLQAGDRVIVSGLQRIRPGIKARAISSSQENASTESKQ"
     gene            5580..5858
                     /locus_tag="IRB70_003842"
     CDS             5580..5858
                     /locus_tag="IRB70_003842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009502656.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633700.1"
                     /translation="MRDLQTSGIVGLSASKVGYRHSDRHGEVNDKKNVAVLPTVPASI
                     RATKGSTGGYIYQGNKVVFASPLVITGGNEISICIPRHASHQFQLLMS"
     gene            complement(5859..6386)
                     /gene="gadE"
                     /locus_tag="IRB70_003843"
     CDS             complement(5859..6386)
                     /gene="gadE"
                     /locus_tag="IRB70_003843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadE"
                     /protein_id="HBC0633701.1"
                     /translation="MIFLMTKDSFLLQGFWQLKDNHEMIKINSLSEIKKVGNNPFKVI
                     IDTYHNHILDEEAIKFLEKLDAERIIVLAPYHISKLKAKAPIYFVSRKESIKNLLEIT
                     YGKHLPHKNSQLCFSHNQFKIMQLILKNKNESNITSTLNISQQTLKIQKFNIMYKLKL
                     RRMSDIVTLGITSYF"
     gene            complement(7185..7757)
                     /gene="hdeD"
                     /locus_tag="IRB70_003844"
     CDS             complement(7185..7757)
                     /gene="hdeD"
                     /locus_tag="IRB70_003844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-resistance protein HdeD"
                     /protein_id="HBC0633702.1"
                     /translation="MLYIDKATILKFDLEMLKKHRRAIQFIAVLLFIVGLLCISFPFV
                     SGDILSTVVGALLICSGIALIVGLFSNRSHNFWPVLSGFLVAVAYLLIGYFFIRAPEL
                     GIFAIAAFIAGLFCVAGVIRLMSWYRQRSMKGSWLQLVIGVLDIVIAWIFLGATPMVS
                     VTLVSTLVGIELIFSAASLFSFASLFVKKQ"
     gene            8012..8344
                     /gene="hdeA"
                     /locus_tag="IRB70_003845"
     CDS             8012..8344
                     /gene="hdeA"
                     /locus_tag="IRB70_003845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeA"
                     /protein_id="HBC0633703.1"
                     /translation="MKKVLGVILGGLLLLPVVSNAADAQKAADNKKPVNSWTCEDFLA
                     VDESFQPTAVGFAEALNNKDKPEDAVLDVQGIATVTPAIVQACTQDKKANFKDKVKGE
                     WDKIKKDM"
     gene            8460..8786
                     /gene="hdeB"
                     /locus_tag="IRB70_003846"
     CDS             8460..8786
                     /gene="hdeB"
                     /locus_tag="IRB70_003846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417966.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid-activated periplasmic chaperone HdeB"
                     /protein_id="HBC0633704.1"
                     /translation="MNISSLRKAFIFMGAVAALSLVNAQSALAANESAKDMTCQEFID
                     LNPKAMTPVAWWMLHEETVYKGGDTVTLNETDLTQIPKVIEYCKKNPQKNLYTFKNQA
                     SNDLPN"
     gene            8850..9497
                     /locus_tag="IRB70_003847"
     CDS             8850..9497
                     /locus_tag="IRB70_003847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBC0633705.1"
                     /translation="MTAEFIIRLILAAIACGAIGMERQMRGKGAGLRTHVLIGMGSAL
                     FMIVSKYGFADVLSLGHVGLDPSRIAAQVVTGVGFIGAGNILVRNQNIVGLTTAADIW
                     VTAAIGMVIGSGMYELGIYGSVMTLLVLEVFHQLTFRLMNKNYHLQLTLVNGNTVSML
                     DWFKQQKIKTDLVSLQENEDHEVVAIDIQLHATTSIEDLLRLLKGMAGVKGVSIS"
     gene            complement(9549..10319)
                     /locus_tag="IRB70_003848"
     CDS             complement(9549..10319)
                     /locus_tag="IRB70_003848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter ATP-binding protein"
                     /protein_id="HBC0633706.1"
                     /translation="MISAQNLVYSLQGRRLTDNVSLTFPGGEIVAILGPNGAGKSTLL
                     RQLTGYLQPDSGECRLFNKPLNEWSITELAKHRAVMRQNSHMAFPFSVQEVIQMGRHP
                     HRTGNQDNETAQIMALCDCQALANRDYRQLSGGEQQRVQLARLLVQLWEPTPSPKWLF
                     LDEPTSALDIHHQQHLFRLLRQLVHERQFNVCCVLHDLNLAARYADRIVLMQKGKVIA
                     NGKPQDVLTQQALTMLYGADITVLKDPANHSPLIVLDH"
     gene            complement(10316..11272)
                     /gene="chuU"
                     /locus_tag="IRB70_003849"
     CDS             complement(10316..11272)
                     /gene="chuU"
                     /locus_tag="IRB70_003849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter permease ChuU"
                     /protein_id="HBC0633707.1"
                     /translation="MGLSLLLLALVLFGASQGALKISFDALFDEEYRDIWLNIRLPRV
                     LLAVLVGAALATAGVIMQGLFRNPMADPGLLGVSSGSALMVGVAIVLPFSFPVVLVLY
                     EQMVFAIAGSLVVCTIIFLITQRHRDGSMMQLLLAGIAINALCGAAIGILSYIGDEQQ
                     LRQLTLWMMGNLGQAQWPTLLVASSFILPAIIATTCLAGTLNLLQLGDEEAHYLGVNV
                     KRKRQQLLLVSSLLVGAAVSVSGIIGFIGLVIPHLIRMTTGANHRWLIPCSALAGACL
                     LLMADTLARTLVQPAEMPVGLLTSLLGGPYFMWLILRNRRIT"
     gene            complement(11357..11980)
                     /gene="chuY"
                     /locus_tag="IRB70_003850"
     CDS             complement(11357..11980)
                     /gene="chuY"
                     /locus_tag="IRB70_003850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobilin reductase"
                     /protein_id="HBC0633708.1"
                     /translation="MTPWLLFGAGGKGVGARTLELALAEQRPVVAVVRHADAATKLAQ
                     QGVQVFTGDACDASVVADACRAAGPDALIISTMGGAQDYLAHRTVIDEAEKAGISRMI
                     LVTSLGCGDSWPFLSERAKAAFGQAVREKTLAESWLQTSQLDYAILRPGGLLDGAATG
                     KAQRIQNQECHGFVHRADVAAHIHELANAPALNQQVYSLIEPDLKPA"
     gene            complement(11980..12474)
                     /gene="hutX"
                     /locus_tag="IRB70_003851"
     CDS             complement(11980..12474)
                     /gene="hutX"
                     /locus_tag="IRB70_003851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme utilization cystosolic carrier protein
                     HutX"
                     /protein_id="HBC0633709.1"
                     /translation="MSHVSLQEFLKTEPDGTLEVVAEQYNTTLLEVVKNLPSSTIVSG
                     DKFDTVWDTVCEWGNVTTLVHTADVILEFSGELPSGFHRHGYFNLRGKHGMSGHIKAE
                     NCTHIALIERKFMGMDTASILFFNKEGSAMLKIFLGRDDHRQLLSEQVSAFHALAASL
                     KEHA"
     gene            complement(12487..13824)
                     /locus_tag="IRB70_003852"
     CDS             complement(12487..13824)
                     /locus_tag="IRB70_003852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme anaerobic degradation radical SAM
                     methyltransferase ChuW/HutW"
                     /protein_id="HBC0633710.1"
                     /translation="MNTNNTLDLTPHFALDGDQPFKDRRAMMPFRGAIPVAKEQLTQT
                     WQEMLNQTVSPRKRLVYLHIPFCATHCTFCGFYQNRFNDDACAHYTDALIREIEMEAD
                     SVLHQSAPIHAVYFGGGTPSALSAHDLARIITTLREKLPLAPDCEITIEGRVLNFDAE
                     RIDACLDAGANRFSIGIQSFNSKIRKKMARTSDGPTAIAFMESLVKRDRAAVVCDLLF
                     GLPGQDAQTWGEDLAIARDIGLDGVDLYALNVLPNTPLGKAVENGRTTVPSPAERRDL
                     YLQGCDFMDDAGWRCISNSHWGRTTRERNLYNLLIKQGADCLAFGSGAGGSINGYSWM
                     NERNLQTWHESVAAGKKPLMMIMRNAERNAQWRHTLQSGVETARVPLDELTPHAEKLA
                     PLLAQWHQKGLSRDASTCLRLTNEGRFWASNILQSLNELIQVLNAPAIVREKP"
     gene            complement(13844..14758)
                     /gene="chuT"
                     /locus_tag="IRB70_003853"
     CDS             complement(13844..14758)
                     /gene="chuT"
                     /locus_tag="IRB70_003853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312409.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme ABC transporter substrate-binding protein
                     ChuT"
                     /protein_id="HBC0633711.1"
                     /translation="MPRIITRPFLFSPLTLCISAVASAAKTMVKRKKLFTALLALSWT
                     FSVTAAERIVVAGGSLTELIYAMGAGKRVVGVDETTSYPPETARLPHIGYWKQLSSEG
                     ILSLRPDSVITWQDAGPQIVLDQLRAQKVNVVTLPRVPATLEQMYANIRQLAKTLQVP
                     EQGEALVTQINQRLERVQQNVAAKKAPVKAMFILSAGGSAPQVAGKGSVADAILSLAG
                     AENVATHQQYKSYSAESLIAANPEVIVVTSQMVDGDINRLRSIAGITHTAAWKNQRII
                     TVDQNLILGMGPRIADVVESLHQQLWPQ"
     gene            15442..17424
                     /gene="chuA"
                     /locus_tag="IRB70_003854"
                     /gene_synonym="shuA"
     CDS             15442..17424
                     /gene="chuA"
                     /locus_tag="IRB70_003854"
                     /gene_synonym="shuA"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent heme/hemoglobin receptor
                     ChuA/ShuA"
                     /protein_id="HBC0633712.1"
                     /translation="MSRPQFTSLRLSLLALAVSATLPTFAFATETMTVTATGNARSSF
                     EAPMMVSVIDTSAPENQTATSATDLLRHVPGITLDGTGRTNGQDVNMRGYDHRGVLVL
                     VDGVRQGTDTGHLNGTFLDPALIKRVEIVRGPSALLYGSGALGGVISYDTVDAKDLLQ
                     EGQSSGFRVFGTGGTGDHSLGLGASAFGRTENLDGIVAWSSRDRGDLRQSNGETAPND
                     ESINNMLAKGTWQIDSAQSLSGLVRYYNNDAREPKNPQTVEASDSSNPMVDRSTIQRD
                     AQLSYKLAPQGNDWLNADAKIYWSEVRINAQNTGSSGEYREQITKGARLENRSTLFAD
                     SFASHLLTYGGEYYRQEQHPGGATTGFPQAKIDFSSGWLQDEITLRDLPITLLGGTRY
                     DSYRGSSDGYKDVDADKWSSRAGMTINPTNWLMLFGSYAQAFRAPTMGEMYNDSKHFS
                     IGRFYTNYWVPNPNLRPETNETQEYGFGLRFDDLMLSNDALEFKASYFDTKAKDYIST
                     TVDFAAATTMSYNVPNAKIWGWDVMTKYTTDLFSLDVAYNRTRGKDTDTGEYISSINP
                     DTVTSTLNIPIAHSGFSVGWVGTFADRSTHISSSYSKQPGYGVNDFYVSYQGQQALKG
                     MTTTLVLGNAFDKEYWSPQGIPQDGRNGKIFVSYQW"
     gene            17473..18501
                     /gene="chuS"
                     /locus_tag="IRB70_003855"
     CDS             17473..18501
                     /gene="chuS"
                     /locus_tag="IRB70_003855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hematinate-forming heme oxygenase ChuS"
                     /protein_id="HBC0633713.1"
                     /translation="MNHYTRWLELKEQNPGKYARDIAGLMNISEAELAFARVTHDAWR
                     MRGDIREILAALESVGETKCICRNEYAVHEQVGAFTNQHLNGHAGLILNPRALDLRLF
                     LNQWASVFHIKENTARGERQSIQFFDHQGDALLKVYATDNTDMAAWSELLARFITDEN
                     TPLELKAVDAPVVQTRADASVVEQEWRAMTDVHQFFTLLKRHNLTRQQAFNLVADDLA
                     CKVSNSALAQILESAQQDGNEIMVFVGNRGCVQIFTGVVEKVVPMKGWLNIFNPTFTL
                     HLLEESIAETWVTRKPASDGYVTSLELFAHDGTQIAQLYGQRTEGEQEQAQWRKQIAS
                     LIPEGVTA"
     gene            complement(18562..19092)
                     /locus_tag="IRB70_003856"
     CDS             complement(18562..19092)
                     /locus_tag="IRB70_003856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0633714.1"
                     /translation="MFLIITRDTMFFTAMKNILSKGNVVHIQNEEEIDVMLHQHAFVI
                     IDTLMNNVFHSNLLTQIERLKPVHVIIFSPFNIKRCLGKVPVTFVPRTITIIDFVALI
                     NGSYCSVPEADVSLSRKQHQVLSCIANQMTTEDILEKLKISLKTFYCHKHNIMMILNL
                     KRINELVRHQHIDYLV"
     gene            complement(19245..>19802)
                     /gene="slp"
                     /locus_tag="IRB70_003857"
     CDS             complement(19245..>19802)
                     /gene="slp"
                     /locus_tag="IRB70_003857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312404.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane lipoprotein Slp"
                     /protein_id="HBC0633715.1"
                     /translation="TKGALILSLSFLLAACSSIPQNIKGNNQPDIQKSFVAVHNQPGL
                     YVGQQARFGGKVINVINGKTDTLLEIAVLPLDSYAKPDIEANYQGRLLARQSGFLDPV
                     NYRNHFVTILGTIQGEQPGFINKVPYNFLEVNMQGIQVWHLREVVNTTYNLWDYGYGA
                     FWPEPGWGAPYYTNAVSQVTPELVK"
BASE COUNT         5181 a         4671 c         4815 g         5135 t
ORIGIN      
        1 atgcaaaact actttgtgga taaattttgg tcctaccaaa tctggcagtt tttgcgctaa
       61 gaaacagtca ggcatcattt cattagtata ctgaaattga aataatcgca gcaatgaaat
      121 ataagggata gtcatgactc atgtctgctc ggtgatcctc gttcgtcgtt cattcgatat
      181 tcatcatgaa cagcaaaaaa tatcgttgca taacgagagt atcctgttac tggataaaaa
      241 tttggcagac gattttgcgt tttgttcacc ggatacacga cgactggata tcgatgagct
      301 gacagtttgc cattacttac aaaatattcg tcagatacca cgcaatttag ggttacatag
      361 caaagaccgt ctgttaatta accagtcacc ccccatgccg ctggtgacgg cgatttttga
      421 tagtttcaat gactccgggg taaattcgcc gatattgagc aaaatgctct atctttcctg
      481 tttatcgatg ttttctcata agaaagaact gatcccctta cttttcaata gtatcagtac
      541 tgtttcagga aaagttgaac gccttattag ctttgatatc gccaaacgtt ggtatctgcg
      601 cgatattgcg gaaagaatgt ataccagcga gagtctcatc aaaaaaaagt tgcaggatga
      661 aaatacctgt ttcagtaaaa tattactcgc ctccaggatg tcgatggcca gacgattact
      721 cgagttacgt caaattcctc tgcatactat tgcggaaaaa tgtggctata gcagtacgtc
      781 gtactttata aacacatttc gacaatatta tggtgtaacg ccacatcagt ttgcgcaaca
      841 ttcgccaggt accttttcct gacatatttt gcatttgaat attggtcagg atctcacacc
      901 tgcttcatgt gaaactcttc cctgatgatt tctgccgggc taccggctag ttctctttcg
      961 cagtttgcca ggcggtatag gtattttcag gaggaaaaga ctcggcatgt ttgggattat
     1021 taagctgaca attcatacga ttacgggaat gtgggtcagt attgtgttgt ttaaattgat
     1081 gacgaatggc tggagtggtt tctactttca gtgctgtgta ctaagcctgg tattcctgac
     1141 ggttagctgg ttgttgagtg gtgaatggtt agcaggaaag agtaaggctg aaccctcacg
     1201 ttcaacctta ctctcattta cacgttacgc ttttttaaag cgggcaaaga gatgttccac
     1261 tacaacgaaa aagaccggaa cgaagtaaat tgccagcact gttgcggcaa acatcccgcc
     1321 catcacgccg gtacctaccg cgttttgcgc gccagaaccg gcaccatgac tgataaccag
     1381 cggcagcacg ccgagaataa aggccagaga ggtcatcagg attgggcgta aacgcatccg
     1441 cgccgcttcg atgattgcct ctatcggcgt tttcccttct ttctgcatca tctcaacggc
     1501 aaattcgaca atcaggatgg cgtttttggc ggaaagcccg atggtggtca gcaaaccaac
     1561 ctggaagtag acgtcattac ttaagccgcg tagatcggtg gccattaatg cgccaacgac
     1621 gcctaacggt acaaccaaca tcaccgagaa cggaattgac cagctctcat aaagtgcggc
     1681 gagggcgagg aacaccacga ccagtgaaat ggcatacagc gcgggagcct gatttgagga
     1741 taacgcttcc tgatacgaca gtccggtcca tgagtagccg acgcctgccg gaagtttagc
     1801 gaccaggtct gccataaatt tcatggcgtc accggtactt ttcccggccg ccgcttcacc
     1861 taaaatctcc attgacggga tgccgttgta gcgttccagt cgcggtgaac cataggtcca
     1921 ttcggtagac gaataggcag aaagcggtgc catcgtgcca gaggcgttgc gtacatacca
     1981 ttggttgatg ttatccggca acatacggaa cggcgtgcct gcctggacat acactttttt
     2041 cacccgcccc tggttgagga agtcgttcac gtagctgctg ccgaaggcgg tggaaattgt
     2101 ctggttgata tcagacagcg ccacccccat agcctcggct ttcgcagcgt tgacgttcac
     2161 tttgaacatc ggcgtatctt ccaggccgtt cgggcgtacc ccgatgacct gattcggtga
     2221 ttgcgctgcc agtgataaca gctcgtttcg cgcctgggtc agtttttcgt gccccagatt
     2281 gccgttgtcc agcagttcca tatcaaaacc tgacgcggta cccagttcag ccaccgcggg
     2341 taagttgaac gggaagacga cggctttatt gatactgctt aacgcaatca ttgcccgctg
     2401 aatgatcgcg gtaaccgagt tttcctcacc gacacgttca gaccacggct tgagactgat
     2461 aaacgccagg ccgttgtttt gcccctggcc gctgaagcca aagccgccaa cggtaaacac
     2521 cgactgaaca ttatctttct ctttagtcag ataataatcc gtcacctgtt gcagcacttt
     2581 cgtggtgtta accatggtgg caccggaagg taactgcgcg gtggtcataa ataccccctg
     2641 atcctcttct ggtaagaaag aggtcggcgt acgcaggaac agcaccgcca tcccggcgca
     2701 aatcagcagg tagaccacca tgtagcgacc ggtacaacgc aacagcgagc gggtgctatc
     2761 ggtatagtgc tgagttgatt tttcaaacag cgtgttgaag cgtgcgaaca gggcgttagg
     2821 tttgtgaccg ccttccggcg cggctttcag aatggtggcg cacagggcag gggtcaggct
     2881 cattgccaca aatactgaaa gcagcatgga ggagatcagc gtgatggaga actggcggta
     2941 gatctccccg gttgcaccgc tcataaaggc catcggcata aacactgcgg aaagaacaac
     3001 ggcaatcccg accagcgcac gttggatctg ccccatcgat ttatgcgtcg cttccttcgg
     3061 cggtagctta tcttccgcaa tgacacgctc gacgttctcc accaccacga tggcgtcatc
     3121 caccagtaac cctatcgcca gcaccatccc gaacatagtt aacgtgttga tggtgaaacc
     3181 gaccgccgac aagatcgcaa acgtcccgag aataaccacc ggtacggcaa tcgtcgggat
     3241 gattgtggcg cggaaattct gcaaaaacag atacatgacc aggaagacga ggatgatagc
     3301 ctcaaccagc gttttgaaaa cttcctgaat agaaattttg ataaacggtg tggtgtcgta
     3361 aggataaacc gtcttcaggc ttgcagggaa ataagccgat aaacggttca gttcctcttt
     3421 gactgcccgc gaggtatcca gggcgtttgc tccggcagcc agtttgatgg cgatccccgc
     3481 agcaggtttg ccgttatagc gcgccacggt ggaataatct tccgccccaa gttcgacgcg
     3541 ggcgacatca cgcagcagca cttgcgagcc atcttgctga actttcaaca ggattttgcc
     3601 aaattcttcc ggcgtttgca gacgcgtctg cacaatgatc gaggcgttca gttgctggtc
     3661 tgccgcctgt ggcatgccac ccagttgacc accggaaatc tggttgtttt gcaccttaat
     3721 ctgggaaata acatcggaag gtaccaggtt atatttattg agtttttgcg ggtccagcca
     3781 gatacgcatg gcgtactcgg aaccaaagag ctgtacgcta ccaacgcccg cggtacggct
     3841 tagcgggtct ttgatattag acgctacata gtccgcgata tcgtactggt tgaggctgcc
     3901 gttatcagaa ataaatgccg ctaccatcag gatattactg ctcgacttat cgacgctaat
     3961 cccctgctgc tgcaccgctt caggtaatga aggcatagcg agttgcagtt tattttgcac
     4021 ctgaacctgt gcgatatcag gcgatgtccc cgtctcgaag gtcagagtga tggaggcatt
     4081 acctgccgca tcgctggttg aagacatgta catcaggcca tcaagcccat tcatattttg
     4141 ctcaatcacc tgagtgaccg agtcttctac cgtttgcgca tcggcacctg gataggtagc
     4201 gctgacggta atggtcggtg gcgcaatctg cggatactgc gcaaccggta agttcatgat
     4261 cgccagaccg cctgcaagca tcataataat ggcaagtacc caggcaaaaa ccgggcgatc
     4321 aataaaatag ttagccatga aagtcccctt aagcctgcaa cgttattgtt tcgattcggt
     4381 gctggcgttt tcctggctgg aggaaattgc tcgtgctttg atacccggac gaatgcgttg
     4441 caaaccggaa acgatcaccc gatcgccagc ctgcaagcca gaggtgacaa cccactggtc
     4501 gccgatggct ttgctggctt cgatttcgcg tagctgcacg acatcgtctt tatccagaat
     4561 gagcgccgtt gctttaccct gggcgttgtg ggtgacgcct tcctgcggca ccagtaatac
     4621 attctggcgg ctaccttcat ccactaatgc cgtgacatac atgccaggca gcaagtcacc
     4681 atttgggttg gggaaaatcg cccgtaacgt cacggagccc gtggtttcat ccaccgtcgg
     4741 gtcggagaat ttcagcgtgc cggtctggct gtaacgttta ccattttcca gattgagctg
     4801 tactggcgta ctgccctgaa cctgtttgat ttgcccactg gcgacctctt ctttcatgcg
     4861 caagaaatcc tgcaccgact gtgtgagatc gacataaatc gggtccagac gttgtacggt
     4921 aaccagcgaa tctgcctgat tagcggtaac gagtgcgccg acggtcaccg acgatttccc
     4981 gctgacgccc gtaatcggcg aggtgacatt cgcgtattgc aggttgatcg tcgcctgttc
     5041 aacagccgct ttggcgacgg tgacattggc ttctgcttca ttcaactggg tgcgcgcggt
     5101 gtcgtaatcc tgacggctaa cgtagttggt cttcagcaac gatgcctggc ggttaaaggt
     5161 gatgcgggca ttgctggcgg tagagagcgc tttcgccagc gtgcctttgg cggagttcag
     5221 ctcggcctgt aaaggtgcag gatcaatctg atacagcgaa tcgccctggt tcactttatc
     5281 gccttcgata aagttgcgtt taatgataat accgcccacc tggggacgta tctcggcaac
     5341 ttcataagga acggttctac cgggcaattc gctcaacaca ttgaccgaac cgggggagag
     5401 tgtgacgaca ccgacctcag gcgtcatggc tgcggcgttt tccgccgatt tgtcatcgca
     5461 ggcggtgagc atcgcgccgc agaataacaa cggtattaac agctttcttc ttctgttcat
     5521 tttagtccct gaaaattctt gagaaataac ggttctttaa attgcgcgcg aggagagata
     5581 tgagggattt acagaccagc ggcatagtgg ggttgtcagc cagtaaggtg ggatacaggc
     5641 acagtgatcg acatggtgag gtcaacgaca aaaaaaatgt tgccgttctg ccaacagttc
     5701 ctgccagcat tcgggcaacg aagggttcta ctggtggata catataccag gggaataaag
     5761 tcgttttcgc ctctccttta gtaatcaccg ggggtaatga aatcagcatc tgcatccctc
     5821 gtcatgccag ccatcaattt cagttgctta tgtcctgact aaaaataaga tgtgataccc
     5881 agggtgacga tgtcgctcat acgtcttagt ttcagtttgt acataatgtt gaatttctga
     5941 atctttaatg tttgttgcga aatattgagc gtcgacgtga tattgctttc atttttattt
     6001 ttcagaatca gttgcataat tttgaactga ttatgtgaaa aacataattg tgaattctta
     6061 tggggcaagt gtttaccata agtaatctca agaagatttt tgatactttc tttgcggctg
     6121 acaaaataaa taggcgcttt agcttttagt ttactgatgt gataaggtgc caaaacaata
     6181 attctctcgg catctaattt ctccagaaat ttaatcgctt cttcatcaag gatatgattg
     6241 tgataggtat caatgataac cttgaagggg ttattgccta cttttttgat ctctgacagg
     6301 gaattgattt ttatcatttc gtgattatct ttcaactgcc aaaagccctg taaaagaaaa
     6361 gaatctttcg tcatgagaaa aatcataact tgctccttag ccgttatcgt ttcgaacatg
     6421 tcatcctttt cattatttac atccttgtcc gaatcgttgt tcaatatagt aaacgcctat
     6481 aagaactttg cccttcgtga actaatacgt ctattaacac taatcaatac ttcagattta
     6541 tccatcacgc actccatata ttggtcctaa gtaagattcc tggttgttat cagtttgtaa
     6601 ctagtaaaca aaaggttaac ttttgcggat tactgcccaa gaataagtta tcaataacca
     6661 gtttgtgatc tctgaagaat attactaaag ttaaaatgta atccgattta aatatcgagt
     6721 ctccttgttt cgacttaggc tggcaattgg attgccagct ttcttttaac gcattgaaat
     6781 tacctgatta aataactcat tcatgtcttc aggtttttat atagcgtctg gagacacgga
     6841 tatttatgca atgtaatcaa cgccagttgc aaaaaaatga acccggatta cttatttaac
     6901 cgcccatagc atcaacgctt acggaactct ttgttcactt tcccacagca cttttaaaac
     6961 attaaacctg accacggaaa atatcagcca tgataatgtt tgaaatggct aatttgccat
     7021 ggaacgaaaa aaatcagatt aaattcagta ggttgaaata atcaacagca ggcaattgtt
     7081 tcaatgatag tgcgtaattg aactgaaaca ctgtatagct aagagagtat taactggatc
     7141 atagtcactt aatgtgacta tgatccaggt ggaaataggg ataattattg ctttttaacg
     7201 aacaaactgg cgaagctgaa cagactggcg gcgctaaata tcagttcaat tcccaccagt
     7261 gtggaaacca gcgttaccga caccatcggc gttgcaccaa ggaatatcca tgcaatgacg
     7321 atatccagca caccaataac gagctgtagc cagctgcctt tcattgaacg ctgacgatac
     7381 caactcatca ggcgaataac ccctgcaaca cagaacaaac cggcaataaa tgccgcaatg
     7441 gcaaaaatgc ccagctccgg tgcgcggatg aagaaatagc cgatcaataa ataggcgact
     7501 gcgacgagga aaccggataa taccggccag aaattatgac tgcggttgct gaataacccg
     7561 acaataagcg caatgcccga gcagattaat aatgcaccca ctactgtgct taaaatgtcg
     7621 ccagagacga acggaaaact gatacacagc aacccgacga taaacagcag cacggcaata
     7681 aactggattg ctctgcgatg ttttttaagc atctccagat caaacttcaa aattgttgcc
     7741 ttatctatat ataacataga accaccctat aaaattaaga agaaaatccc ctgctatcaa
     7801 tctatgccaa aaacgcgtct aagaatgcag tcgatttaat aaaaatttcc taattacagt
     7861 atctgatgca tctgtaactc attgtattga aataaaaata tctgattttg atattttcca
     7921 tcaacatgac atatacagaa aaccaggtta taacctcagt gtcgaaattg attcgtgacg
     7981 gctctttcac tttatagttg aggatattac gatgaaaaaa gtattaggcg ttattcttgg
     8041 tggtctgctt cttctgccag ttgtgagcaa tgcagcggat gcgcaaaaag cagctgataa
     8101 caaaaaaccg gtcaactcct ggacctgtga agatttcctg gctgtggacg aatccttcca
     8161 gccaactgca gttggttttg ctgaagcgct gaacaacaaa gataaaccag aagatgcggt
     8221 tttagatgtt cagggtattg caaccgtaac cccagctatc gttcaggctt gtactcagga
     8281 taaaaaagcc aactttaaag ataaagttaa aggcgaatgg gacaaaatta agaaagatat
     8341 gtaattccgg gaatgcgtta catcgtactt ccttgcatat tgaacaggcc ggaatatctt
     8401 ctttaaaagc agctattcct cctgttcata tataatctct atattgaatg ggttacaaaa
     8461 tgaatatttc atctctccgt aaagcgttta tttttatggg cgctgtagcg gctttgtcac
     8521 tggtgaacgc acaatctgcg ctggcagcca atgaatccgc taaagatatg acctgccagg
     8581 aatttattga tctgaatcca aaagcaatga caccggttgc atggtggatg ctgcatgaag
     8641 aaacagtata taaaggtggc gatactgtta ctttaaatga aaccgatctc actcaaattc
     8701 ctaaagtgat cgaatactgc aagaaaaacc cgcagaaaaa tttgtatacc ttcaaaaatc
     8761 aagcatctaa tgacttgccg aattaatgag gtacaagtaa aaaggagtag caagttgagc
     8821 catcttgctg ctcctttttg catttttata tgacagcaga atttattata cgtcttatac
     8881 tcgcagcaat tgcctgtggc gctattggca tggaaaggca aatgcgcggc aaaggagcag
     8941 ggttacgcac acatgtatta attggcatgg gaagcgccct gtttatgatt gtttcgaaat
     9001 atggttttgc tgacgtgctg tctttaggtc acgtcggact ggatcccagc cgtattgctg
     9061 ctcaggttgt gacgggcgtc gggtttatcg gtgcaggtaa cattctcgtt cgtaaccaaa
     9121 atattgtagg tctgacgacg gcagcggata tctgggtgac cgccgccatt ggtatggtta
     9181 ttggcagcgg tatgtacgaa ctgggtattt atggttcagt gatgaccttg ctggtgctgg
     9241 aagtcttcca tcaattaacc ttccgcctga tgaacaaaaa ttaccattta cagctgacat
     9301 tagtgaacgg taatacggta tcaatgctcg actggtttaa gcagcaaaaa ataaaaacgg
     9361 atttagtttc gttgcaggaa aatgaagatc atgaagtggt cgccattgat atccagcttc
     9421 atgccacgac gtcgatagaa gatctgttgc gattattaaa aggtatggca ggggtgaaag
     9481 gcgtttcaat tagctaatct gtatagttat ttattcgcag gagtaccagt gcggtactcc
     9541 tgttggtttt aatgatcgag gacgatcagt ggtgaatggt tggcaggatc tttaagtacg
     9601 gtaatatccg cgccgtaaag catggtcagc gcctgctgtg tcaatacgtc ctgtggttta
     9661 ccatttgcga taacctttcc tttttgcatt aatacaatac ggtctgcata acgcgcggca
     9721 agatttagat cgtgcaatac gcagcaaaca ttgaactgcc gttcgtgaac taactggcgt
     9781 aataaacgga acaagtgctg ctgatggtga atatccagcg ccgaagttgg ttcatcaaga
     9841 aataaccatt tcggtgaggg agttggttcc cagagttgca ccagcaggcg cgctaattgt
     9901 acgcgctgtt gttcaccacc ggataattgc cgatagtcgc ggtttgctaa cgcctgacag
     9961 tcacataacg ccattatttg tgctgtttca ttatcctgat taccagtgcg atgcggatgc
    10021 cgccccatct ggataacttc ttgtacgctg aatggaaacg ccatgtggct attttgacgc
    10081 atcacggccc ggtgtttcgc cagttcagta atcgaccatt catttaatgg cttattaaac
    10141 aaccgacatt cgccgctatc aggttgaaga tagccggtta actggcgaag cagcgtagat
    10201 tttcccgcac cattagggcc gagaatggca acaatttccc caccgggaaa agtcagcgag
    10261 acattatcag tcagacgccg cccctgaagg ctataaacca gattctgggc gctgatcatg
    10321 tgatcctccg gttgcgcaga atcaaccaca taaaataagg accaccaagc aggctggtta
    10381 ataatcccac gggcatttct gctggctgta ccagcgtgcg ggcaagcgtg tctgccatca
    10441 gcaataaaca ggctccggcg agggcggagc aagggattag ccagcggtga tttgctccgg
    10501 tagtcatgcg aatcagatgc gggatcacca ggccaataaa gccgataatg ccgcttaccg
    10561 atacggcggc accaacgagc agtgagctca ctaacagtaa ttgctggcgt ttacgcttaa
    10621 cgttcacgcc gaggtaatgg gcttcttcat caccgagctg cagtaaattc agcgttccgg
    10681 cgagacaagt tgttgcgata atggccggta ggatgaatga actggcaacc aataacgtcg
    10741 gccattgcgc ctgtccaaga ttgcccatca tccacaatgt gagttgtcgt agctgctgct
    10801 catcgccgat atagctcagg atgccgatcg ctgcgccgca cagggcattg atggcgatac
    10861 cggcgagtaa taattgcatc atgctgccat cgcgatggcg ctgcgtgatg agaaaaatga
    10921 tggtgcagac cactaaactt ccggcaatgg caaacaccat ttgctcatag agcaccagca
    10981 ccactgggaa ggagaagggc agcacaatag caacgccaac cattaatgca gaaccgctac
    11041 tgacgccaag taatccaggg tcagccattg ggttgcgaaa aagcccctgc ataattaccc
    11101 ctgcggttgc caacgctgca cctaccagca ccgccagcaa aacccgtggt agacgaatat
    11161 tgagccagat atcgcggtat tcctcatcaa aaagggcatc aaaactgatc tttaacgctc
    11221 cctgactggc accgaacagc accagagcta gcaataatag tgatagcccc ataaagaccc
    11281 tggcggaaga gagtgaatcc ttgagcacgc aaaactccgt tacgacatta cggcgcggac
    11341 atgccgcgcc ggggtatcac gccggtttca ggtccggttc aatcagactg tagacctgct
    11401 ggttaagtgc tggcgcattt gccagttcat ggatatgtgc ggcgacatcg gcacggtgaa
    11461 caaaaccatg acactcctga ttttgtatcc gttgtgcttt gcccgttgcc gccccatcta
    11521 gcagaccgcc agggcggaga atggcgtaat caagctggct ggtttgcaac cagctttccg
    11581 ccagcgtttt ttcccgtacc gcctgaccaa acgcagcctt tgctcgctcc gataaaaatg
    11641 gccagctatc gccgcatccc aaagaggtca ccagaatcat gcgactgatg ccggcctttt
    11701 cggcctcatc aatcactgtt ctgtgcgcca gataatcctg agctccgccc attgttgaga
    11761 tgataagcgc atccgggcca gctgcgcggc aagcatccgc gactacgctg gcatcacagg
    11821 cgtcgcctgt aaaaacctgt acgccttgtt gcgccagttt cgtggcggca tcggcatgac
    11881 gaacgacagc aacgaccgga cgttgctctg ccagcgccag ttcaagcgtt ctggcaccca
    11941 caccttttcc gcctgcgcca aagagtagcc acggcgtcat caggcgtgtt cctttaacga
    12001 tgctgccaga gcatggaagg cgctgacttg ttcgctcagg agctgacgat ggtcatccct
    12061 gccgaggaag attttcagca tggcgctgcc ttccttattg aaaaagagaa tagaggcggt
    12121 gtccatgccc ataaatttac gttcgatcaa ggcaatatgt gtgcagtttt ctgctttgat
    12181 atgcccggac atgccgtgct ttccgcgtag gttgaaatag ccgtggcggt ggaaacccga
    12241 aggcagttcg ccgctaaatt cgaggattac atcggcagta tgtactaacg tggtgacgtt
    12301 gccccattcg cagacggtat cccagacagt atcgaattta tcgcctgaca ctatggtaga
    12361 ggagggcaga tttttcacta cttccagcag tgtggtgttg tattgttcgg ctaccacctc
    12421 cagcgtaccg tccggctccg ttttcaaaaa ttcttgtaac gagacatggc tcataaatca
    12481 ctcctgttat ggtttttcac gcacaatcgc tggcgcatta agtacctgaa ttagttcatt
    12541 aagagactgc aaaatattgc ttgcccagaa acgaccttca ttagtcagcc gcaggcaagt
    12601 tgaagcatcg cgacttaagc ctttttggtg ccattgagcc agtaacggcg cgagtttttc
    12661 ggcatgtggt gtaagttcat ccagcggtac gcgcgctgtt tcaacacctg actgcaaggt
    12721 atgacgccat tgcgcattac gttcggcgtt acgcatgatc atcatcagcg gttttttgcc
    12781 tgccgcgacg gattcatgcc aggtctgaag attgcgttcg ttcatccagg agtaaccatt
    12841 aatcgaaccg ccggctccgg aaccaaaggc cagacaatcg gcaccttgtt taatcagcag
    12901 gttatagaga ttgcgttcgc gtgtggtacg gccccagtgg ctgttactga tgcagcgcca
    12961 accggcatcg tccataaaat cacacccttg caggtaaaga tcgcgacgtt ctgccggaga
    13021 gggcacggta gtacgcccat tttccacggc tttgcccagc ggtgtattgg gcaggacatt
    13081 gagcgcatag agatcgacgc cgtcgagacc gatatcgcgg gcaatagcca gatcttctcc
    13141 ccaggtttgc gcatcctgac ccggcagacc aaacagcagg tcacagacca ccgcggcacg
    13201 gtcgcgtttg accaggcttt ccataaacgc aatagcggtt gggccatccg aggtgcgggc
    13261 cattttcttg cggattttgc tgttaaacga ctgaatacca attgagaagc ggtttgctcc
    13321 agcatcaagg caagcatcga ttcgctcagc gtcaaaattc agtacccggc cttcaatagt
    13381 gatttcacaa tcaggggcca gtggcagctt ttctcgtaat gtggtgatga ttctggccaa
    13441 atcgtgtgct gaaagcgcgg aaggcgtacc gccaccgaaa tagaccgcgt ggatgggggc
    13501 agactgatgc aatacgctgt ctgcttccat ttctatttca cgaatcaggg cgtcggtata
    13561 atgagcacac gcatcgtcat taaaacggtt ctgataaaaa ccacaaaacg tgcagtgtgt
    13621 cgcacaaaaa ggaatgtgta gataaaccag tcgcttacgt ggtgataccg tttgattgag
    13681 catctcttgc caggtctgtg tcagttgctc tttggcaact ggaatggccc cacgaaacgg
    13741 catcatggcg cgcctgtctt taaatggctg atcaccgtct aaagcaaaat gtggcgtgag
    13801 atccagggtg ttatttgtgt tcattcgtct gatttaaatc catttattgc ggccaaagct
    13861 gctggtgtaa agactcaacg acatcagcaa tacgcggacc cattcccaga atcaggtttt
    13921 gatcaacggt gataatgcgc tggtttttcc atgcggcagt gtgggtaatt ccggcaatag
    13981 aacgtagccg attaatatcg ccatcgacca tttgtgaggt gacgacaatc acttcagggt
    14041 tagccgcaat cagcgattcc gcgctgtagc ttttgtactg ctggtgggta gcgacgtttt
    14101 ctgctccggc aagcgaaaga atggcgtccg cgacgctgcc tttaccggca acctgtggcg
    14161 cacttccgcc tgcggagaga ataaacatgg ctttaaccgg ggcttttttg gccgccacgt
    14221 tttgctgtac tcgctccagg cgttggttga tctgtgtcac cagcgcctcg ccttgttcag
    14281 gaacctgtaa cgtttttgcc agttggcgaa tgttggcgta catctgctca agggtggctg
    14341 gtacacgcgg cagagtgacg acgttgactt tttgcgcccg cagttggtcg agcacaattt
    14401 gcggtcctgc atcctgccag gtaattacgc tatccgggcg aagtgacaaa atgccttcgc
    14461 tgctgagttg tttccagtaa ccaatatgcg gcagtctggc ggtttctggt ggataagatg
    14521 tcgtttcatc gacaccaacc acgcgtttgc cagcgcccat cgcgtagatt agctccgtca
    14581 gcgatcctcc tgcgaccacg atacgttcgg cagccgttac gctaaaagtc cagctaagag
    14641 ccagtaatgc cgtaaacaat ttttttcgtt ttaccatggt cttcgcggca gaggccacgg
    14701 ctgaaataca taacgtcagt ggggaaaaaa gaaacggcct ggtgatgatc cttggcataa
    14761 tatgagaacc cttatcaaat tgagaatgat catgattatc atttgagtta tatatgaaat
    14821 acaaccgtcg attcaatacg cacggcgtta caagcgtatt tatttttgat ttttatcaag
    14881 atgcttcgtc agctaatgtt cttgttaccg attaaatttc agcgcgggaa aaagctgaga
    14941 acccggagat atcgcggctt gcagagcaaa gagaagagaa aattatcact gttaacgaca
    15001 acgttttgtg atgaggttgt ggggggatag ccataaacac aggatggttt tctggatgct
    15061 ggatagattt cataaccccc tgtttattgt gttaatggcg gttaaaaaaa gcttgatcat
    15121 aaaaaattga tcgataataa ttctcattat cacgtttgag tttaacaaaa tatgacatca
    15181 tggataacaa aatcatatct tttgtaaggg aaaacgcaca gcactcttca cttcagacgt
    15241 ggcgtactac tttgcctgac aaagagggcg tgcttttgct gaattatcag aaatattcgg
    15301 caattttacg ggatatatac gctaatagct tcccgtggtg atatctaatc atttgaattg
    15361 taaataaatt tatttttcgc cagccacccc ggtattaacc caggcagcca gcatttttta
    15421 ttttcctcat ggagaatcgc tatgtcacgt ccgcaattta cctcgttgcg tttgagtttg
    15481 ttggctttgg ctgtttctgc caccttgcca acatttgctt ttgctactga aaccatgacc
    15541 gttacggcaa ccgggaatgc acgtagttcc ttcgaagcgc ctatgatggt cagcgttatc
    15601 gacacttccg ctcctgaaaa tcaaacggct acttcagcca ctgatttgct gcgtcatgtt
    15661 cctggaatta ctcttgatgg taccggacga accaacggtc aggatgtaaa tatgcgtggc
    15721 tatgatcatc gcggcgtgct ggttcttgtc gatggtgttc gccagggaac ggataccgga
    15781 cacctgaatg gcacttttct cgatccggcg ctgatcaagc gtgttgagat tgttcgcgga
    15841 ccttcagcat tactgtatgg cagtggcgcg ctgggtggag tgatctccta cgatacggtc
    15901 gatgcaaaag atttattgca ggaaggacaa agcagtggtt ttcgtgtctt tggtactggc
    15961 ggcacggggg accatagcct gggattaggc gcgagcgcgt ttgggcgaac tgaaaatctg
    16021 gatggtattg tggcctggtc cagtcgcgat cggggtgatt tacgccagag caatggtgaa
    16081 accgcgccga atgacgagtc cattaataac atgctggcga aagggacctg gcaaattgat
    16141 tcagcccagt ctctgagcgg tttagtgcgt tactacaaca acgacgcgcg tgaaccaaaa
    16201 aatccgcaga ctgttgaggc ttctgatagc agcaacccga tggttgatcg ttcaacaatt
    16261 caacgcgatg cgcagctttc ttataaactc gccccacagg gcaacgactg gttaaatgca
    16321 gatgcaaaaa tttactggtc ggaagtccgt attaatgcgc aaaacacggg gagttccggc
    16381 gagtatcgtg aacagataac aaaaggagcc aggctggaga accgttccac tctatttgcc
    16441 gacagtttcg cttctcactt actgacatat ggcggtgagt attatcgtca ggaacaacat
    16501 ccgggcggcg cgacgacggg cttcccgcaa gcaaaaatcg attttagctc cggctggcta
    16561 caggatgaga tcaccttacg cgatctgccg attactctgc ttggcggaac ccgctatgac
    16621 agttatcgcg gtagcagcga cggctacaaa gatgttgatg ctgacaaatg gtcatctcgt
    16681 gcggggatga ctatcaaccc gaccaactgg ctgatgttat ttggctcata tgcccaggca
    16741 ttccgcgccc cgacgatggg cgaaatgtat aacgattcta agcacttctc gattggtcgc
    16801 ttctatacca actattgggt gccaaacccg aacttacgtc cggaaactaa cgaaactcag
    16861 gagtacggtt ttgggctgcg ttttgatgac ctgatgttgt ccaatgatgc tctggaattt
    16921 aaagccagct actttgatac caaagcgaag gattacatct ccacgaccgt cgatttcgcg
    16981 gcggcgacaa ctatgtcgta taacgtcccg aacgccaaaa tctggggctg ggatgtaatg
    17041 acgaaatata ccactgatct gtttagcctt gatgtggcct ataaccgtac ccgcggcaaa
    17101 gacaccgata ctggggaata tatctccagc attaacccgg ataccgttac cagtaccctg
    17161 aatattccga tcgctcacag tggcttctct gttgggtggg ttggtacgtt tgccgatcgc
    17221 tcaacacata tcagcagcag ttacagcaaa caacctggct atggtgtgaa tgatttctac
    17281 gtcagttatc aaggacaaca ggcgctcaaa ggcatgacca ctactctggt attgggcaac
    17341 gccttcgata aagagtactg gtcgccgcaa ggcatcccac aggatggtcg taacggaaaa
    17401 attttcgtga gttatcaatg gtaatcatct gccccgatat ttcggggcat ttatctggaa
    17461 ggaagagaga caatgaacca ctacacacgc tggcttgagt taaaagaaca aaatcccgga
    17521 aagtacgcgc gtgacatcgc aggtttaatg aatatcagcg aagcagaact ggcatttgcg
    17581 cgcgtcacgc acgacgcgtg gcggatgcgc ggcgatatcc gtgaaattct ggcggcgctc
    17641 gaaagtgttg gcgaaaccaa atgtatttgc cgtaatgaat atgcagtcca tgagcaagtt
    17701 ggtgcgttca caaaccagca tttgaacgga catgccggat tgatcctcaa tccgcgcgcg
    17761 ctggatttac gtctgtttct caatcaatgg gccagtgttt tccacatcaa agaaaacacg
    17821 gctcgtggcg aacgccagag tattcagttc tttgatcatc agggcgatgc attactaaaa
    17881 gtttatgcca ccgacaatac cgatatggcg gcatggagtg agcttctggc acggtttatc
    17941 accgatgaga atacgccgct tgagttaaaa gccgttgatg cgccagttgt tcaaacgcga
    18001 gccgatgcca gtgtggtcga gcaagagtgg cgggcgatga ccgacgttca tcagtttttt
    18061 acgttgctca agcgccacaa cctgacgcgc caacaggcgt tcaatctggt ggcagacgat
    18121 ttggcctgca aagtatccaa cagtgcgttg gcgcaaattc ttgaatctgc acagcaggat
    18181 ggcaatgaaa tcatggtgtt tgttggcaac cgtggctgcg tacagatttt caccggtgtg
    18241 gtagaaaaag tggtgccaat gaaaggttgg ctgaatattt ttaacccgac gtttactctt
    18301 catctattag aagagagcat tgctgaaacc tgggtaaccc gtaaacctgc tagtgacggt
    18361 tatgtgacca gtctggaatt gtttgcccat gatggtacgc agatagcgca actttatggt
    18421 caacgtacag aaggcgaaca ggagcaagcg caatggcgta agcaaattgc ttcgctgata
    18481 ccggaaggcg ttactgcata acgtataatt aaagggaggt ctggctattt attgctgggc
    18541 ctctttatat taatcaatcg atcacaccag ataatcaata tgctgatggc gtaccaactc
    18601 attgatccgc ttaagattga ggatcatcat gatattgtgt ttatggcagt agaacgtttt
    18661 tagcgatatt ttcagtttct ccagaatatc ttccgttgtc atttgattcg caatgcagct
    18721 cagaacctga tgctgcttgc gcgaaaggga cacatccgct tcaggcacag agcagtaact
    18781 gccattgatg agtgcgacaa agtcgatgat ggtgatagtt cgcggaacaa aggtcaccgg
    18841 tactttcccc aggcagcgtt taatattaaa gggagagaaa ataatcacat ggacaggttt
    18901 taatcgttca atttgagtga gcaaattaga atgaaataca ttattcatta atgtatcaat
    18961 aatgacgaag gcatgctgat gcaacattac gtcgatctct tcttcgttct gtatatgaac
    19021 gacattacct ttactcagaa tgtttttcat cgcagtgaag aacatcgtat ccctggtaat
    19081 tataagaaac ataaccgact cctggtgcgg acattaactt tataatcagt ttgccaaagg
    19141 taattaacag gacagggctt ataataataa ttagcttact gtgtattaat ttgatgtaat
    19201 gcatgatgca gatgctgaga aagcatctgc atctttcggt ggtgttattt gaccagctca
    19261 ggtgttacct gactcaccgc gttggtgtag taaggcgcac cccagcccgg ttccggccag
    19321 aatgcaccat agccgtaatc ccacaggtta taggtggtat taaccacttc tctcaaatgc
    19381 cacacctgga tgccctgcat attcacttcg aggaagttat acgggacttt attgataaag
    19441 ccaggttgtt caccctgaat ggtaccgagg atggtaacaa agtgattacg atagttcact
    19501 ggatcaagga agccgctttg tctggcgagc agtcggccct gatagttggc ttcaatatca
    19561 ggcttcgcat agctatccaa cggtaataca gcgatttcta acaacgtatc cgttttgcca
    19621 ttgataacgt tgataacctt cccaccaaag cgcgcttgtt gaccaacata taaccccggc
    19681 tggttatgaa cagcaacaaa acttttttga atatcaggtt ggttattgcc tttgatattt
    19741 tgcggaattg aactacatgc ggcaagcaaa aatgaaaggc tgaggatgag tgcacctttt
    19801 gt
//
LOCUS       DADXDL010000095        19707 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.095, whole genome shotgun sequence.
ACCESSION   DADXDL010000095 DADXDL010000000
VERSION     DADXDL010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19707)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19707)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19707
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.095"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            83..889
                     /locus_tag="IRB70_003858"
     CDS             83..889
                     /locus_tag="IRB70_003858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBC0633716.1"
                     /translation="MQTWLNLQDKIIIVTGGASGIGLAIVDELLAQGANVQMVDIHGG
                     DGQYEGHKGYQFWPTDISSAKEVNHTVAEIIQRFGRIDGLVNNAGVNFPRLLVDEKAP
                     AGQYELNEAAFEKMVNINQKGVFLMSQAVARQMVKQHDGVIVNVSSESGLEGSEGQSC
                     YAATKAALNSFTRSWSKELGKHGIRVVGIAPGILEKTGLRTPEYEEALAWTRNITVEQ
                     LREGYTKNAIPIGRAGRLAEVADFVCYLLSERASYITGVTTNIAGGKTRG"
     gene            899..1306
                     /locus_tag="IRB70_003859"
     CDS             899..1306
                     /locus_tag="IRB70_003859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sorbose transporter subunit IIA"
                     /protein_id="HBC0633717.1"
                     /translation="MVNAIFCAHGKLACAMLESVQMVYGDARVEAVEFVPGENAGDIV
                     AKLEKLVSIHNQDEWLIAVDLQCGSPWNAAAMLAMRNPRLRVISGLSLPLALELVDNQ
                     DSMNIDELCEHLTQIAKQICVVWRQVATAEEDF"
     gene            1306..1800
                     /locus_tag="IRB70_003860"
     CDS             1306..1800
                     /locus_tag="IRB70_003860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system
                     mannose/fructose/N-acetylgalactosamine-transporter subunit
                     IIB"
                     /protein_id="HBC0633718.1"
                     /translation="MNITLARIDDRLIHGQVTTVWSKVANAQRIIICNDEVYNDEVRR
                     TLLRQAAPPGMKVNVVNIEKAVAVYHNPQYQDETVFYLFTRPQDALAMVRQGVKIGTL
                     NIGGMAWRPGKKQLTKAVSLDDDDINAFHELNNLGVILDLRVVASDPSINIIDKINEQ
                     LIAN"
     gene            1866..2663
                     /locus_tag="IRB70_003861"
     CDS             1866..2663
                     /locus_tag="IRB70_003861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBC0633719.1"
                     /translation="MEISTLQIIAIFLFSCIAGMGSVLDEFQTHRPLIACTVIGLILG
                     DLKTGIMLGGTLELIALGWMNVGAAQSPDSALASIISAILVIVGQQSIATGIAIALPV
                     AAAGQVLTVFARTITVVFQHAADKAAEEARFRTLDILHVSALGVQALRVAIPALIVSL
                     FVSADMVSNMLSAIPEFVTRGLQIAGGFIVVVGYAMVLRMMGVKYLMPFFFLGFLAGG
                     YLDLSLLAFGGVGVIMALLYIQLNPQWRKAEPHPQTTTITALDQLDD"
     gene            2674..3498
                     /locus_tag="IRB70_003862"
     CDS             2674..3498
                     /locus_tag="IRB70_003862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBC0633720.1"
                     /translation="MEQRKITRSDLVSMFLRSNLQQASFNFERIHGLGFCYDMIPAIK
                     RLYPLKEDQVAALRRHLVFFNTTPAVCGPVIGVTAAMEEARANGAEIDDGTINGIKVG
                     LMGPLAGVGDPLVWGTLRPITAALGASLALSGNILGPLLFFFIFNAVRLTMKWYGLQL
                     GFRKGVNIVSDMGGNLLQKLTEGASILGLFVMGVLVTKWTSINVPLVVSQTPAADGAT
                     VTMTVQNILDQLCPGLLALGLTLLMVRLLNKKINPVWLIFALFGLGIIGNALGFLS"
     gene            3550..4779
                     /gene="sorE"
                     /locus_tag="IRB70_003863"
     CDS             3550..4779
                     /gene="sorE"
                     /locus_tag="IRB70_003863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-sorbose 1-phosphate reductase"
                     /protein_id="HBC0633721.1"
                     /translation="MKTTALRLYGKRDLRLETFDLPEMQEDEILATVVTDSLCLSSWK
                     EANLGENHKKVPDDVATNPIIIGHEFCGDILAVGKKWQHKFQPGQRYVIQANLQLPDR
                     PDCPGYSFPWVGGEATHVVIPNEVMEQDCLLAYDGETYFEGSLVEPLSCVIGAFNANY
                     HLQEGSYNHTMGIRPQGRTLILGGTGPMGLLAIDYALHGPVNPSLLVITDTDNDKLSY
                     ARKHYPSEPQTLIHYLNATDAAFDTLMALSGGHGFDDIFVFVPNEGLVTLASSLLATD
                     GCLNFFAGPQDKHFSAPINFYDVHYAFTHYVGTSGGNTDDMRAAVKLIEEKKVQAAKV
                     VTHILGLNAAGETTLELPAVGGGKKLVYTGKYLPLTSLTQIQDEELAAILARHQGVWS
                     GEAEQYLLAHAEAISHD"
     gene            4772..5584
                     /locus_tag="IRB70_003864"
     CDS             4772..5584
                     /locus_tag="IRB70_003864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000610343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate 5-dehydrogenase"
                     /protein_id="HBC0633722.1"
                     /translation="MINRDTQLCMSLAGRPGNFGTRFHNYLYEKLGLNFIYKAFTTQD
                     IAAAVKGVRALGIRGCAVSMPFKESCMPFLDAIDPSAKVIDSVNTIVNDDGRLTGFNT
                     DYIAVKSLITHHQLNTTTRVMIRGSGGMGKAVIAAFRDAGFTDVIIAARNRESGPALA
                     KQYGFQWQPQPEGIACDILVNVTPVGMSGGKESHELAFSEAMVSTASVVFDVVALPPE
                     TPLIRLAQRLDKQTISGAEVIALQAVEQFAMYTGVRPDAQLIAEAAQFAREG"
     gene            5707..6396
                     /gene="pepE"
                     /locus_tag="IRB70_003865"
     CDS             5707..6396
                     /gene="pepE"
                     /locus_tag="IRB70_003865"
                     /EC_number="3.4.13.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepE"
                     /protein_id="HBC0633723.1"
                     /translation="MELLLLSNSTLPGKAWLEHALPLIAEQLQGRRSAVFIPFAGVTQ
                     TWDDYTAKTAAVLAPLGVSVTGIHSVVDPVAAIENAEIVIVGGGNTFQLLKQCRERGL
                     LPPITDVVKRGALYIGWSAGANLACPTIRTTNDMPIVDPQGFDALNLFPLQINPHFTN
                     ALPEGHKGETREQRIRELLVVAPELTIIGLPEGNWITVSKGHATLGGPNTTYVFKAGE
                     EAVPLEAGHRF"
     gene            complement(6486..8117)
                     /locus_tag="IRB70_003866"
     CDS             complement(6486..8117)
                     /locus_tag="IRB70_003866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na/Pi cotransporter family protein"
                     /protein_id="HBC0633724.1"
                     /translation="MLTLLHLLSAVALLVWGTHIVRTGVMRVFGARLRTVLSRSVEKK
                     PLAFCAGIGVTALVQSSNATTMLVTSFVAQDLVALAPALVIVLGADVGTALMARILTF
                     DLSWLSPLLIFIGVIFFLGRKQSRAGQLGRVGIGLGLILLALELIVQAVTPITQANGV
                     QVIFASLTGDILLDALIGAMFAIISYSSLAAVLLTATLTAAGIISFPVALCLVIGANL
                     GSGLLAMLNNSAANAAARRVALGSLLFKLVGSLIILPFVHLLAETMGKLPLPKAELVI
                     YFHVFYNLVRCLVMLPFVDPMARFCKTIIRDEPELDTQLRPKHLDVSALDTPTLALAN
                     AARETLRIGDAMEQMMEGLNKVMHGEPRQEKELRKLADDINVLYTAIKLYLARMPKEE
                     LAEEESRRWAEIIEMSLNLEQASDIVERMGSEIADKSLAARRAFSLDGLKELDALYEQ
                     LLSNLKLAMSVFFSGDVTSARRLRRSKHRFRILNRRYSHAHVDRLHQQNVQSIETSSL
                     HLGLLGDMQRLNSLFCSVAYSVLEQPDEDEGRDEY"
     gene            complement(8337..12020)
                     /gene="metH"
                     /locus_tag="IRB70_003867"
     CDS             complement(8337..12020)
                     /gene="metH"
                     /locus_tag="IRB70_003867"
                     /EC_number="2.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBC0633725.1"
                     /translation="MSSKVEQLRAQLNERILVLDGGMGTMIQSYRLNEADFRGERFAD
                     WPCDLKGNNDLLVLSKPEVIAAIHNAYFEAGADIIETNTFNSTTIAMADYQMESLSAE
                     INFAAAKLARACADEWTARTPEKPRYVAGVLGPTNRTASISPDVNDPAFRNITFDQLV
                     AAYRESTKALVEGGADLILIETVFDTLNAKAAVFAVKTEFEALGVELPIMISGTITDA
                     SGRTLSGQTTEAFYNSLRHAEALTFGLNCALGPDELRQYVQELSRIAECYVTAHPNAG
                     LPNAFGEYDLDADTMAKQIREWAQAGFLNIVGGCCGTTPQHIAAMSRAVEGLAPRKLP
                     EIPVACRLSGLEPLNIGEDSLFVNVGERTNVTGSAKFKRLIKEEKYSEALDVARQQVE
                     NGAQIIDINMDEGMLDAEAAMVRFLNLIAGEPDIARVPIMIDSSKWDVIEKGLKCIQG
                     KGIVNSISMKEGVDAFIHHAKLLRRYGAAVVVMAFDEQGQADTRARKIEICRRAYKIL
                     TEEVGFPAEDIIFDPNIFAVATGIEEHNNYAQDFIGACEDIKRELPHALISGGVSNVS
                     FSFRGNDPVREAIHAVFLYYAIRNGMDMGIVNAGQLAIYDDLPTELRDAVEDVILNRR
                     DDGTERLLELAEKYRGSKTDDTANTQQAEWRSWEVNKRLEYSLVKGITEFIEQDTEEA
                     RQQATRPIEVIEGPLMDGMNVVGDLFGEGKMFLPQVVKSARVMKQAVAYLEPFIEASK
                     EQGKTNGKMVIATVKGDVHDIGKNIVGVVLQCNNYEIVDLGVMVPAEKILRTAKEVNA
                     DLIGLSGLITPSLDEMVNVAKEMERQGFTIPLLIGGATTSKAHTAVKIEQNYSGPTVY
                     VQNASRTVGVVAALLSDTQRDDFVARTRKEYETVRIQHGRKKPRTPPVTLEAARDNDF
                     AFDWQAYTPPVAHRLGVQEVEASIETLRNYIDWTPFFMTWSLAGKYPRILEDEVVGVE
                     AQRLFKDANDMLDKLSAEKMLNPRGVVGLFPANRVGDDIEIYRDETRTHVINVSHHLR
                     QQTEKTGFANYCLADFVAPKLSGKADYIGAFAVTGGLEEDALADAFEAQHDDYNKIMV
                     KALADRLAEAFAEYLHERVRKVYWGYAPNENLSNEELIRENYQGIRPAPGYPACPEHT
                     EKATIWELLEVEKHTGMKLTESFAMWPGASVSGWYFSHPDSKYYAVAQIQRDQVEDYA
                     RRKGMSVSDVERWLAPNLGYDAD"
     gene            12220..13044
                     /gene="iclR"
                     /locus_tag="IRB70_003868"
     CDS             12220..13044
                     /gene="iclR"
                     /locus_tag="IRB70_003868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418442.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate bypass operon transcriptional
                     repressor IclR"
                     /protein_id="HBC0633726.1"
                     /translation="MVAPIPAKRGRKPAVATAPATGQVQSLTRGLKLLEWIAESNGSV
                     ALTELAQQAGLPNSTTHRLLTTMQQQGFVRQVGELGHWAIGAHAFMVGSSFLQSRNLL
                     AIVHPILRNLMEESGETVNMAVLDQSDHEAIIIDQVQCTHLMRMSAPIGGKLPMHASG
                     AGKAFLAQLSEEQVTKLLHRKGLHAYTHATLVSPVHLKEDLAQTRKRGYSFDDEEHAL
                     GLRCLAACIFDEHREPFAAISISGPISRITDDRVTEFGAMVIKAAKEVTLAYGGMR"
     gene            complement(13061..14785)
                     /gene="aceK"
                     /locus_tag="IRB70_003869"
     CDS             complement(13061..14785)
                     /gene="aceK"
                     /locus_tag="IRB70_003869"
                     /EC_number="2.7.11.5"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional isocitrate dehydrogenase
                     kinase/phosphatase"
                     /protein_id="HBC0633727.1"
                     /translation="MPRGLELLIAQTILQGFDAQYGRFLEVTSGAQQRFEQADWHAVQ
                     QAMKNRIHLYDHHVGLVVEQLRCITNGQSTDAAFLLRVKEHYTRLLPDYPRFEIAESF
                     FNSVYCRLFDHRSLTPERLFIFSSQPERRFRTIPRPLAKDFHPDHGWESLLMRVISDL
                     PLRLRWQNKSRDIHYIVRHLTETLGTDNLAESHLQVANELFYRNKAAWLVGKLITPSG
                     TLPFLLPIHQTDDGELFIDTCLTTTAEASIVFGFARSYFMVYAPLPAALVEWLREILP
                     GKTTAELYMAIGCQKHAKTESYREYLVYLQGCNEQFIEAPGIRGMVMLVFTLPGFDRV
                     FKVIKDRFAPQKEMSAAHVRACYQLVKEHDRVGRMADTQEFENFVLEKRHISPALMEL
                     LLQEAAEKITDLGEQIVIRHLYIERRMVPLNIWLEQVEGQQLRDAIEEYGNAIRQLAA
                     ANIFPGDMLFKNFGVTRHGRVVFYDYDEICYMTEVNFRDIPPPRYPEDELASEPWYSV
                     SPGDVFPEEFRHWLCADSRIGPLFEEMHADLFRADYWRALQNRIRDGHVEDVYAYRRR
                     QRFSVRFV"
     gene            complement(14871..16175)
                     /gene="aceA"
                     /locus_tag="IRB70_003870"
     CDS             complement(14871..16175)
                     /gene="aceA"
                     /locus_tag="IRB70_003870"
                     /EC_number="4.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isocitrate lyase"
                     /protein_id="HBC0633728.1"
                     /translation="MKTRTQQIEELQKEWTQPRWEGITRPYSAEDVVKLRGSVNPECT
                     LAQLGAAKMWRLLHGESKKGYINSLGALTGGQALQQAKAGIEAVYLSGWQVAADANLA
                     ASMYPDQSLYPANSVPAVVERINNTFRRADQIQWSAGIEPGDPRYVDYFLPIVADAEA
                     GFGGVLNAFELMKAMIEAGAAAVHFEDQLASVKKCGHMGGKVLVPTQEAIQKLVAARL
                     AADVTGVPTLLVARTDADAADLITSDCDPYDSEFITGERTSEGFFRTHAGIEQAISRG
                     LAYAPYADLVWCETSTPDLELARRFAQAIHAKYPGKLLAYNCSPSFNWQKNLDDKTIA
                     SFQQQLSDMGYKFQFITLAGIHSMWFNMFDLANAYAQGEGMKHYVEKVQQPEFAAAKD
                     GYTFVSHQQEVGTGYFDKVTTIIQGGTSSVTALTGSTEESQF"
     gene            complement(16205..17806)
                     /gene="aceB"
                     /locus_tag="IRB70_003871"
     CDS             complement(16205..17806)
                     /gene="aceB"
                     /locus_tag="IRB70_003871"
                     /EC_number="2.3.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate synthase A"
                     /protein_id="HBC0633729.1"
                     /translation="MTEQATTTDELAFIRPYGEQEKQILTAEAVEFLTELVTHFTPQR
                     NKLLAARIQQQQDIDNGTLPDFISETASIRDADWKIRGIPADLQDRRVEITGPVERKM
                     VINALNANVKVFMADFEDSLAPDWNKVIDGQINLRDAVNGTISYSNEAGKIYQLKPNP
                     AVLICRVRGLHLPEKHVTWRGEAIPGSLFDFALYFFHNYQALLAKGSGPYFYLPKTQS
                     WQEAAWWSEVFSYAEDRFNLPRGTIKATLLIETLPAVFQMDEILHALRDHIVGLNCGR
                     WDYIFSYIKTLKNYPDRVLPDRQAVTMDKPFLNAYSRLLIKTCHKRGAFAMGGMAAFI
                     PSKDEERNNQVLNKVKADKSLEANNGHDGTWIAHPGLADTAMAVFNDILGSRKNQLEV
                     MREQDAPITADQLLAPCDGERTEEGMRANIRVAVQYIEAWISGNGCVPIYGLMEDAAT
                     AEISRTSIWQWIHHQKTLSNGKPVTKALFRQMLGEEMKVIASELGEERFSQGRFDDAA
                     RLMEQITTSDELIDFLTLPGYRLLA"
     gene            complement(18075..19004)
                     /gene="metA"
                     /locus_tag="IRB70_003872"
     CDS             complement(18075..19004)
                     /gene="metA"
                     /locus_tag="IRB70_003872"
                     /EC_number="2.3.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005132837.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="homoserine O-succinyltransferase"
                     /protein_id="HBC0633730.1"
                     /translation="MPIRVPDELPAVNFLREENVFVMTTSRASGQEIRPLKVLILNLM
                     PKKIETENQFLRLLSNSPLQVDIQLLRIDSRESRNTPAEHLNNFYCNFEDIQEQNFDG
                     LIVTGAPLGLVEFNDVAYWPQIKQVLEWSKDHVTSTLFVCWAVQAALNILYGIPKQTR
                     TDKLSGVYEHHILHPHALLTRGFDDSFLAPHSRYADFPAALIRDYTDLEILAETEEGD
                     AYLFASKDKRIAFVTGHPEYDAQTLAQEYFRDVEAGLDPEVPYNYFPHNDPQNKPRAS
                     WRSHGNLLFTNWLNYYVYQITPYDLRHMNPTLD"
     gene            19161..19604
                     /locus_tag="IRB70_003873"
     CDS             19161..19604
                     /locus_tag="IRB70_003873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBC0633731.1"
                     /translation="MVISIRRSRHEEGEELVAIWCRSVDATHDFLSAEYRAELEELVR
                     SFLPEAPLWVAVNERDRLVGFMLLSGQHMDALFVDPDARGCGVGRMLVEHALSMAPEL
                     TTNVNEQNKQAVGFYKKMGFKVTGRSEVDDLGKPYPLLNLAYVGE"
BASE COUNT         4584 a         5222 c         5237 g         4664 t
ORIGIN      
        1 attactgaaa taaaaatctt cccgatgttt accgtaataa aaattacggc gggtccctat
       61 tatctaaaat caggagtctg ttatgcaaac gtggttaaat ttgcaggata aaatcattat
      121 tgtcaccggt ggcgcatccg gcattggtct ggcgattgtg gatgaattat tagcacaagg
      181 cgcgaatgta cagatggtcg atattcacgg tggcgatgga caatatgaag gtcataaagg
      241 ctatcagttt tggccgaccg atatttccag cgccaaagag gtaaatcata cggtagcaga
      301 aattatccag cgttttggtc gcatcgacgg tctggtcaat aacgccgggg tcaatttccc
      361 gcgtctgctg gtcgatgaga aagcgcctgc cgggcagtat gaactcaacg aagctgcatt
      421 cgaaaaaatg gtcaatatca accagaaagg cgtttttctg atgtcgcagg cggtggcgcg
      481 acagatggtc aaacaacacg atggcgtgat tgtgaatgtt tcctcagaaa gtgggctgga
      541 aggctcagaa ggccagagct gctacgccgc cactaaagct gcgctcaata gcttcactcg
      601 ctcctggtcg aaagaactgg gtaagcacgg tatccgtgtg gtcggtatcg cgccggggat
      661 tctggaaaaa acaggactgc gcacgccgga atatgaagaa gcgctggcgt ggacgcgcaa
      721 tatcaccgtc gagcagctgc gtgaaggcta taccaaaaac gccattccta ttgggcgcgc
      781 cggaagatta gcagaagtgg ctgattttgt ttgttatctg ctgtctgaac gcgccagcta
      841 tatcaccgga gtaaccacta acattgcggg cggcaaaacg cgcggctaag gaggctttat
      901 ggtcaatgcc attttttgcg cccatggcaa attagcttgc gccatgctgg aatcggttca
      961 gatggtgtac ggcgatgcca gggtcgaggc cgttgaattt gtgcccggcg agaacgccgg
     1021 agacatcgta gcaaagctgg aaaagttagt aagcattcac aatcaagatg agtggctgat
     1081 tgccgtggat ttacagtgcg gcagcccgtg gaatgcggca gcgatgcttg cgatgcgcaa
     1141 tcctcgtctg cgggtaatca gcggcctttc tctgccgctg gcgctcgaac tggttgataa
     1201 ccaggacagc atgaatattg atgaactgtg tgaacacctg acgcaaatcg caaagcaaat
     1261 ctgcgtcgtc tggagacagg tggcaacagc ggaggaggat ttctgatgaa cattacgctc
     1321 gcccgcattg atgaccgcct gatccacggc caggtcacta ccgtctggtc taaagtggct
     1381 aacgcccaac gcattattat ctgcaatgac gaagtttata acgatgaagt tcgccggaca
     1441 ttattgcgtc aggctgcgcc accgggaatg aaggttaacg tggtcaatat tgaaaaagcc
     1501 gtcgcggttt atcacaaccc gcaatatcag gacgaaaccg ttttttatct tttcactcgc
     1561 ccacaagatg ccttagcaat ggttcgccag ggggtaaaaa taggtaccct gaatattggc
     1621 ggtatggcct ggcgtcctgg taagaaacag ttaaccaaag cagtttcatt agatgacgat
     1681 gatattaacg catttcatga gttaaataat cttggcgtca tactggattt acgcgtcgta
     1741 gcgtcagatc cctcaatcaa tattatcgac aaaataaacg aacagttaat cgcaaattaa
     1801 ataatagcgc ctgtgtacat atgctttaac aggcagggat gacgacactt aaaaggtgac
     1861 aaatcatgga aataagtacc ctacaaatta ttgctatatt tcttttttcc tgtattgccg
     1921 gaatgggcag cgtgctggat gaatttcaga ctcatcgtcc gttaattgcc tgtacggtga
     1981 ttggtttaat tctcggtgat ttaaaaaccg gaattatgct cggtggtacg ctggaattga
     2041 tagctctcgg ctggatgaac gtcggcgcgg cgcaatctcc ggattctgca ctcgccagca
     2101 taatctccgc cattctggtt atcgttggtc agcaaagcat cgccaccgga atcgccatcg
     2161 cgttgcctgt ggctgcggca ggccaggtgc tgacggtgtt tgcccgtacc atcaccgtag
     2221 tgttccagca cgcggcggat aaagcagcgg aagaagcacg gtttcgcact ctcgatattc
     2281 tgcatgtctc cgcgcttggc gtgcaggcat tgcgcgttgc gattccggca ctgattgtct
     2341 cgctgttcgt cagcgccgat atggtgagca atatgctgag cgccattccc gaatttgtga
     2401 cccgtggact gcagattgct ggcggtttta tcgtggtggt cggttacgcc atggtgcttc
     2461 gcatgatggg cgtgaaatat ttgatgcctt tctttttcct cggtttcctc gcaggtggct
     2521 acctcgatct cagtctgctg gcgttcggtg gcgtcggcgt gatcatggcc ctgctctaca
     2581 tccagttaaa tccacagtgg cgtaaagctg aaccacatcc ccagaccacc actatcaccg
     2641 cccttgacca acttgatgat taacggagcc atcatggaac agagaaaaat tacacgcagc
     2701 gatctggtga gcatgtttct gcgctccaac ctgcaacagg catcctttaa ctttgaacgt
     2761 attcacgggc tgggtttttg ctacgacatg atccccgcca tcaaacgact ttacccatta
     2821 aaagaggatc aggttgcggc gctcaggcga cacctggtgt tcttcaatac cacgccagcc
     2881 gtatgtggcc cggtcatcgg cgtcactgcc gccatggaag aggcgcgagc caacggcgcg
     2941 gaaattgatg acggtaccat taacggcatc aaagtcggcc tgatgggacc gttggcaggt
     3001 gttggcgatc cactggtctg gggaacgctg cgcccgatta ccgccgcgct cggcgcatct
     3061 ctggcacttt cgggcaacat tctcggcccc ctgctgttct tctttatttt caatgcagta
     3121 cgtctgacaa tgaaatggta tgggctgcaa ctgggctttc gtaaaggggt gaatatcgtc
     3181 agcgatatgg gcggtaattt gctgcaaaaa ctgaccgaag gcgcgtcgat tctcgggctg
     3241 tttgtaatgg gcgtactggt gaccaaatgg acatcgatca acgtgccgtt agtggtttca
     3301 caaacgcctg ccgccgatgg tgccaccgtc actatgaccg tacagaacat tctcgaccag
     3361 ctttgccctg gattgctggc gctcggtttg acgctgctga tggtacgtct gctcaacaaa
     3421 aaaattaacc cggtatggct gattttcgcc ctgtttggtt tagggattat cggtaatgcg
     3481 ctgggcttcc tgtcctgatt cttcgccccg gcacgactgc cggggtcatc gctcaacatg
     3541 aggtggttta tgaaaacaac agctctgcgt ctttatggca aacgtgacct gcgtctggaa
     3601 acctttgacc ttcctgaaat gcaggaggat gaaatcctcg cgacggtggt cactgacagc
     3661 ctgtgcctct cttcctggaa agaggccaat ctgggggaaa accataaaaa agtacccgac
     3721 gatgtggcga ccaatcccat catcatcggc cacgaatttt gcggcgatat tctggccgtg
     3781 ggtaaaaagt ggcagcacaa attccagccg ggtcagcgtt atgtgattca ggccaacctg
     3841 caactccccg accgcccgga ctgccccggc tactccttcc cgtgggtagg cggcgaagcg
     3901 acgcatgtgg ttattcccaa cgaggtcatg gaacaagatt gcctgctggc atacgacggc
     3961 gaaacctatt ttgaaggctc gctggttgaa ccgctttcct gcgtgattgg cgcgttcaac
     4021 gccaactatc atcttcagga aggtagttat aaccacacga tggggattcg cccgcaaggg
     4081 cgcacgctga tcctcggcgg caccggacca atgggactgt tggcgattga ttatgcgcta
     4141 catggacccg ttaacccttc gctgctcgtc attaccgata ccgacaacga caaattgagt
     4201 tatgcgcgca agcactatcc atcagaaccg caaacactga ttcattatct caatgccacc
     4261 gatgcagcat ttgatacgtt aatggcgctg agtggcggtc acggcttcga tgatattttc
     4321 gtctttgtgc ctaatgaagg actggtgact ctcgcctctt ccttgctggc gacagatggt
     4381 tgcctgaatt tcttcgccgg accgcaggat aagcacttca gcgcgccaat taatttctac
     4441 gatgtgcatt atgcatttac ccactacgta ggcacgtcag gcggcaatac cgacgacatg
     4501 cgcgcagcgg tcaaattgat tgaagagaaa aaagtgcagg ccgcaaaagt ggtaacacat
     4561 attcttgggc tgaatgccgc gggcgaaacc acgcttgaat tgcctgccgt cggcggcggg
     4621 aaaaaactgg tgtataccgg gaaatatctg ccgctgacat cactcacgca gattcaggat
     4681 gaagaactgg cggcgattct ggcgcgtcat cagggagtct ggtctggcga ggcggagcag
     4741 tacctgctcg cccatgcaga ggcgatttcc catgattaat cgcgatactc aactctgcat
     4801 gtcgctggcc ggccgccccg gtaacttcgg cacgcgtttt cacaattatc tttatgaaaa
     4861 gctggggctg aatttcatct ataaagcgtt caccacccag gatattgcag cggcggtgaa
     4921 aggggttcgc gcgttgggta ttcgcggttg cgctgtgtcg atgccgttta aagaaagctg
     4981 catgcctttt ctcgacgcga tcgatccgtc ggcgaaggtc attgattccg tgaataccat
     5041 cgtgaatgac gacggcaggc tgaccgggtt taacaccgac tatatcgcgg tgaaaagcct
     5101 gattacccac caccagctca ataccaccac gcgagtgatg attcgcggca gtggcggcat
     5161 gggcaaagcg gtgattgccg cctttcgcga cgcggggttt acggatgtta tcattgccgc
     5221 ccgcaaccgc gagagcggcc cggcgctggc gaagcagtat gggtttcagt ggcaaccgca
     5281 gccggaaggc atcgcctgcg acattctggt caacgtgacg cccgttggca tgagcggcgg
     5341 taaagagagc catgagctgg ccttcagcga agcgatggtc tcaacggcaa gcgtcgtttt
     5401 tgatgtcgtg gccttgccgc cggaaacgcc gctcattcgc ctggcgcaac ggcttgataa
     5461 gcagacgatt agcggtgcgg aggtgattgc tttacaggcc gtcgagcagt tcgcaatgta
     5521 taccggcgta cggcctgatg cgcaactgat tgctgaggcg gcacaatttg cacgagaagg
     5581 ataagaaaca tcagcgcctt gtttgccacg ccagaagcaa tgcgcaacat cgtgagccat
     5641 gtcagtaagc ggttaaaatc acagtggtag catggctccc gtgatttctt actaaccgga
     5701 gaagtaatgg aactgctttt attgagtaac tcgacgctgc cgggtaaagc ctggctggaa
     5761 cacgcgctgc cgctgattgc tgaacagttg cagggtcgcc gttcagcggt atttattcct
     5821 ttcgctggcg taacgcagac ctgggatgat tacacagcga aaacggctgc ggttctcgct
     5881 ccgctgggtg tttctgtcac cggtattcat agcgttgtcg atcccgttgc cgcgattgaa
     5941 aatgctgaga tcgtgattgt cggcggcggt aatactttcc agttgctgaa acagtgccgc
     6001 gagcgcgggc tgctgccacc aattactgac gtggtgaaac gtggcgcgct gtatattggc
     6061 tggagcgcag gcgctaacct tgcttgccca accattcgta ccaccaacga tatgccgatt
     6121 gtcgatccgc aaggtttcga tgcgctgaat ctgttcccgt tgcaaatcaa cccgcacttc
     6181 accaacgcgc tgccggaagg ccataaaggt gaaacgcgtg agcagcgtat tcgcgaactg
     6241 ctggtcgtcg cgccagaact cacaattatt ggtctaccgg aaggtaactg gatcacggtg
     6301 agtaaaggtc acgctacgct gggtggcccg aacaccactt atgtgtttaa ggctggtgaa
     6361 gaagcggtgc cgctggaagc gggtcaccgt ttttaaatga attgccggat gcatgatccg
     6421 gcatcttgtt catcgtgcct gatgcgacgc tttacgcgtc ttatcaggcc tacagggtca
     6481 cggtattaat actcgtcccg tccttcgtct tcatccggct gttccagcac actgtaagcc
     6541 accgaacaaa acagcgagtt cagacgctgc atatctccca gtaagcctaa atgtagcgaa
     6601 ctggtttcaa tgctttgcac gttttgctga tgcaggcgat cgacgtgagc atgggaataa
     6661 cggcgattaa gaatgcgaaa gcgatgcttg ctgcggcgca aacgacgggc gctggtaaca
     6721 tcgccagaga agaaaaccga cattgccagt tttaaattac tgagcaattg ctcatagagc
     6781 gcatccagtt ccttcaagcc atcaagcgaa aatgcccgcc gtgctgccag cgatttatcg
     6841 gcaatttcgc tccccatgcg ctcgacgata tcggaggcct gttcaaggtt gagcgacatt
     6901 tcgatgatct ccgcccagcg gcgcgactct tcctccgcca gctcttcttt tggcatccgc
     6961 gccagataca gcttaatggc ggtatagaga acgttgatat catcagccag cttacgcagc
     7021 tctttctcct gccgtggctc gccgtgcatc actttattca acccttccat catctgttcc
     7081 atggcgtcgc caatgcgcag ggtttcgcgg gcagcgttcg ccagagcaag cgtgggcgta
     7141 tccagcgcgc tgacatccag atgtttaggc cgtagctggg tatccagttc cggttcatcg
     7201 cgaataatcg ttttgcaaaa ccgtgccatc gggtcaacga atggcaacat gaccaggcag
     7261 cgtacaaggt tgtagaagac gtggaaatag atcaccagtt ccgcttttgg caatggcaac
     7321 ttccccattg tctctgccag caaatgaaca aacggcagga taatcaggct acccaccagc
     7381 ttaaacagca ggctacccag cgcgacacgg cgggctgcgg cattggcggc actgttgttg
     7441 agcatcgcca gcagaccgga accgaggtta gcaccaatca ccagacagag cgccacgggg
     7501 aaggagataa tgcctgcggc ggtcagagtc gcggtcagca gtacagcagc aaggctggag
     7561 tagctgataa tggcgaacat cgcgccaatc agcgcatcca gcagaatatc gccggtcagc
     7621 gaggcaaaga tcacctgaac gccgtttgcc tgggtgatcg gcgttacggc ctgcacaatc
     7681 aactccagcg ccagcaaaat cagcccaaga ccaataccga cgcggcccag ttgcccggcg
     7741 cgtgactgtt tgcgtccgag gaaaaaaatc acgccgataa aaataagtaa cggtgacagc
     7801 caggataagt cgaaggtgag aatacgcgcc attagcgccg tcccgacatc tgcacccagc
     7861 acaatcacca gagccggtgc gagggctacc agatcctgag cgacaaacga ggtcaccagc
     7921 atggtggtgg cattactgct ctgcaccagt gcggtaacgc ctatccccgc gcaaaaggcg
     7981 agcggcttct tttcgacgct tcggctaaga acagtacgca gacgcgcgcc gaagacgcgc
     8041 attacgccgg ttcgaacaat atgagtcccc cagaccagca gggcgacggc agaaagcagg
     8101 tgaagcagcg ttaacacgag ttcaggttct ccttatcgtt atatgttcct gaagcaattg
     8161 aatgaccaaa ggaccggaaa cacgctgact ggcatcttta ctgtgccttt tgacattcgt
     8221 ttttccggct aagattattc cagcctgttt ccagtataag tgtttcatat taataaagag
     8281 acagggcact cattgagcgc cctgtttgtt gtaaggaaaa gtgacagatt tgtgaatcag
     8341 tccgcgtcat accccagatt cggtgccagc cagcgctcaa catctgagac gctcatacct
     8401 ttacggcggg catagtcttc aacctgatcg cgctggattt gcgccaccgc gtaatacttg
     8461 ctgtccgggt ggctgaaata ccaacccgaa accgatgcac cgggccacat ggcgaaagat
     8521 tctgtgagtt tcatgccggt atgtttttcc acttccagca gctcccagat ggtggctttt
     8581 tccgtatgtt ccgggcaggc cggatagccc ggtgccggac ggatgccctg gtagttttcg
     8641 cggatcagct cttcgttgct gaggttctcg ttcggcgcat agccccagta gactttacgc
     8701 acacgctcat ggagatactc cgcaaaggct tccgccagac ggtctgcaag ggctttcacc
     8761 atgattttgt tgtaatcatc gtgctgcgct tcaaaggcat cagccagtgc gtcctcttcc
     8821 agcccgccag tcacggcaaa tgcgccgatg taatctgctt taccagaaag cttcggcgca
     8881 acgaagtcag cgagacagta gttagcgaag ccggtttttt cggtctgttg gcgcagatgg
     8941 tggctgacgt tgatcacatg ggtacgcgtt tcgtcacggt agatttcaat gtcatcgccc
     9001 acacggtttg ccgggaacag gcccaccacg ccacgcgggt tcagcatttt ttcggcgctt
     9061 aatttatcca gcatgtcgtt ggcgtcttta aacagccgct gcgcctcaac acctaccact
     9121 tcatcttcca gaatgcgcgg atacttcccg gccagcgacc aggtcataaa gaacggcgtc
     9181 cagtcgatgt aattacgcag cgtttcgatg ctggcttcga cttcctgcac accgagacgg
     9241 tgcgccaccg gcggcgtgta agcctgccag tcaaaagcga agtcgttatc acgcgccgct
     9301 tccagcgtga ccggtggtgt gcgtggtttc tttcgtccgt gctgaatacg cacggtttcg
     9361 tactccttgc gggtacgagc aacgaaatca tcgcgctgag tgtcggaaag caacgccgcc
     9421 accacaccaa cggtgcgtga agcgttctgc acatacaccg tcgggccgct gtagttctgc
     9481 tcaattttca ccgccgtgtg cgcttttgag gtggtcgcgc cgccaatcaa tagcggaatg
     9541 gtgaagccct gacgctccat ctctttcgcc acgttaacca tctcgtccag cgacggcgtg
     9601 atcagccccg aaaggccaat caaatcagca ttcacttctt tagcggtacg gagaattttt
     9661 tccgcaggca ccatcacgcc gagatcgaca atttcgtagt tgttacattg cagcaccacg
     9721 ccaacgatat ttttaccgat gtcgtggaca tcgcccttca ctgtggcgat caccatcttg
     9781 ccgttggttt taccctgctc tttgctggct tcaatgaacg gctcgagata cgccaccgcc
     9841 tgtttcatga cgcgcgccga tttcaccacc tgcggcagga acattttgcc ctcgccaaac
     9901 aggtcgccga ccacgttcat gccgtccatc aacgggcctt caatcacttc aatcggacgc
     9961 gtagcctgct ggcgggcttc ttcggtatcc tgctcgataa actcggtaat gcctttgacc
    10021 agcgagtatt ccagacgttt attcacttcc cacgaacgcc actctgcctg ctgggtgtta
    10081 gcggtgtcgt cggttttgct gccgcgatat ttctcggcaa gctcgagtaa acgctcggtg
    10141 ccatcgtcgc gacggttgag gatcacatcc tccaccgcgt cgcgtagctc ggtaggcagg
    10201 tcgtcgtaaa tcgccaattg cccggcgttg acgatcccca tatccatgcc attgcgaata
    10261 gcgtagtaga ggaacaccgc gtgaatggct tcgcgcaccg gatcgttgcc acggaatgag
    10321 aaagaaacgt tagaaacgcc gccggaaatc agtgcgtgcg gcagttcacg tttgatgtct
    10381 tcacacgcgc cgataaagtc ctgcgcgtaa ttgttgtgct cttcaatgcc agttgcgacc
    10441 gcgaagatgt tcgggtcgaa gatgatatct tcagccggga agccaacctc ttcggtgagg
    10501 attttgtacg cccgacggca aatctcgatt ttccgtgcgc gggtatcggc ctggccctgt
    10561 tcgtcaaaag ccattaccac gactgccgca ccgtaacgac gcaacaattt cgcgtgatgg
    10621 ataaaagcgt cgacgccttc tttcatcgaa atagagttaa caatgccttt gccctggata
    10681 cacttcagac ctttttcaat gacatcccat tttgaggagt cgatcataat cggcacgcga
    10741 gcgatatccg gttcaccggc aatcagattg agaaaacgca ccatcgccgc ttcggcgtcg
    10801 agcatccctt catccatgtt gatatcgata atctgcgcac cgttttccac ctgctgacgc
    10861 gccacatcca gcgcctcgct gtatttctct tctttgatca ggcgcttgaa cttagcggaa
    10921 ccggtgacgt tggtgcgttc acccacgttc acaaacaggc tatcttcgcc aatgttcagc
    10981 ggctccaggc cggacaaacg gcaggctacg gggatttccg gcagtttgcg cggcgctaat
    11041 ccttctactg cacgactcat cgctgcaata tgttgtggcg tggtgccaca gcagccgccg
    11101 acgatattga gaaagcccgc ttgcgcccat tcacgtatct gttttgccat cgtgtcggcg
    11161 tcgagatcgt actcaccaaa ggcgttgggt agcccggcgt ttgggtgcgc ggtgacgtag
    11221 cattccgcaa tccgtgacag ctcctgcacg tactggcgca gttcgtctgg ccccagcgca
    11281 cagttaaggc cgaaagtcag cgcttcggcg tggcgcagag agttataaaa cgcttcggtg
    11341 gtctgcccgg agagcgtgcg cccggaggcg tcggtgatgg tgccggagat cataatcggc
    11401 agctcaacgc ccagcgcttc aaactccgtt ttcaccgcaa aaaccgccgc tttggcgtta
    11461 agggtgtcga aaacggtttc gatcaggatc agatccgcac caccttccac cagcgctttg
    11521 gtggattcgc gataggccgc caccagctgg tcaaaagtga tgttgcggaa tgccggatcg
    11581 ttgacgtccg gagaaataga cgccgtgcgg ttggtcgggc cgagaacacc ggcaacgtag
    11641 cgcggtttct ccggcgtgcg cgcggtccac tcatcagcac aggcgcgcgc cagtttcgcc
    11701 gccgcaaagt tgatttccgc cgacagggat tccatctggt aatccgccat cgcaatggtt
    11761 gtggagttga aggtgttggt ttcgatgata tccgcgcccg cttcaaagta ggcgttgtgg
    11821 atagcggcga tcacttccgg tttactgagt accagcaggt cgttgttgcc tttgaggtcg
    11881 catggccagt cggcaaagcg ttcaccacga aaatcggctt cgttcagtcg atagctctgg
    11941 atcatggtgc ccataccgcc gtccagcacc agaatacgtt catttaactg cgcacgcagt
    12001 tgttccactt tgctgctcac acttgctccc gacacgctca acccagattt aataaaaatt
    12061 caacaaacca tactggcata aacgcatctg tggtaaaagc gaccaccacg caacatgaga
    12121 tttgttcaac attaactcat cggatcagtt cagcaactat tgcattagct aacaataaaa
    12181 atgaaaatga tttccacgat acagaaaaag gagactgtca tggtcgcacc cattcccgcg
    12241 aaacgcggca gaaaacccgc cgttgccacc gcaccagcga ctggacaggt tcagtcttta
    12301 acgcgtggcc tgaaattact ggagtggatt gccgaatcca atggcagtgt ggcactcacg
    12361 gagctggcgc aacaagccgg gttacccaat tccacgaccc accgcctgct aaccacgatg
    12421 caacagcagg gtttcgtgcg tcaggttggc gaactgggac actgggcaat cggcgcacat
    12481 gcctttatgg tcggcagcag ctttctccag agccgtaatt tgttagcaat tgttcaccct
    12541 atcctgcgca atttaatgga agagtctggc gaaacggtca atatggcggt gcttgatcaa
    12601 agcgatcatg aagcgattat tatcgaccag gtacagtgta cccacctgat gcgaatgtcc
    12661 gcgcctatcg gcggtaaatt acctatgcac gcttccggtg cgggtaaagc ctttttagcc
    12721 caactgagcg aagaacaggt gacgaagctg ttgcaccgca aagggttaca tgcctatacc
    12781 cacgcaacgc tggtgtctcc tgtgcattta aaagaagatc tcgcccaaac gcgcaaacgg
    12841 ggttattcat ttgacgatga ggaacatgcg ctggggctac gttgccttgc agcgtgtatt
    12901 ttcgatgagc accgtgaacc gtttgccgca atttctattt ccggaccgat ttcacgtatt
    12961 accgatgacc gcgtgaccga gtttggcgcg atggtgatta aagcggcgaa ggaagtgacg
    13021 ctggcgtacg gtggaatgcg ctgacttttt cgcctctgat ttatacgaat cgaacgctaa
    13081 acctctgcct acgccgatac gcataaacat cttccacatg cccgtcacgg atacggtttt
    13141 gtagcgcgcg ccagtagtcg gcgcggaaca ggtcggcgtg catctcttca aacagtggcc
    13201 caatacgcga gtcggcgcat agccaatggc gaaactcttc cgggaaaaca tcgcccggcg
    13261 agacgctgta ccacggctca ctggcaagtt cgtcctccgg gtagcgcggc ggcgggatgt
    13321 cgcggaaatt cacttccgtc atgtagcaaa tttcatcgta atcataaaac accacacgcc
    13381 cgtgacgggt gacaccgaag tttttaaaca gcatgtcgcc agggaaaatg ttagcagcgg
    13441 caagctggcg aatagcgtta ccgtattctt caatggcgtc gcgcagctgc tgaccttcca
    13501 cttgttccag ccagatattg agcggcacca tccgccgctc gatataaaga tggcgaatca
    13561 caatttgttc gccgagatcg gtgatttttt ccgctgcttc ctggagcagt aattccatta
    13621 atgccgggga aatatgccgc ttctccagca caaagttttc aaactcctgg gtgtccgcca
    13681 ttcggcccac acgatcgtgc tctttcacca gttggtagca ggcacgaacg tgagcggcag
    13741 acatctcttt ctgcggcgcg aacctgtctt tgatgacttt gaagacccga tcaaaacccg
    13801 gcaacgtaaa caccagcatc accatgccac gaatacccgg cgcttcaatg aactgctcat
    13861 tacagccctg tagataaacg agatattcgc ggtagctttc ggttttagcg tgcttctggc
    13921 agccgatagc catatacaat tcagcggtgg ttttacctgg cagaatttcc cgtagccact
    13981 cgaccagcgc tgcgggcagc ggtgcataaa ccataaaata agaacgcgca aagccaaaaa
    14041 caatgctcgc ttcggcggtc gtcgtcaggc aagtatcaat aaataactcg ccgtcgtccg
    14101 tctggtggat cggcagcaaa aatggcaatg tgccggaagg cgtgatcagt ttgcccacca
    14161 gccaggcggc tttattgcgg taaaacagtt cgttcgccac ctgtaaatga ctttccgcga
    14221 ggttgtctgt ccccagcgtt tccgtcagat ggcgaacgat gtaatgaatg tcacggcttt
    14281 tattctgcca gcgcagacgc aacggcaggt cgctgataac acgcatcagc agagattccc
    14341 agccgtgatc ggggtgaaag tctttcgcca gcgggcgcgg aatggtacga aaacggcgct
    14401 ctggctggga gctaaagata aaaagccgct cgggagtaag cgagcggtgg tcaaataacc
    14461 gacagtacac ggagttaaaa aagctctccg caatctcgaa gcgcgggtaa tccggcaaca
    14521 gccgcgtgta atgctctttg acgcgcagta aaaatgccgc gtccgtgctt tggccgttgg
    14581 taatgcagcg cagttgctcc accaccagac ccacgtgatg atcgtaaaga tggatacggt
    14641 ttttcatcgc ctgctggaca gcatgccagt cggcctgttc gaaacgctgc tgcgccccgg
    14701 aagtcacttc gaggaatcga ccatactgag catcgaagcc ttgcaaaatg gtttgtgcaa
    14761 tcagtaattc caggccacgc ggcatttagc gccctcatca ggagcagaga attgccggat
    14821 gcggcgtaaa tgccttatcc ggcctacagt cagcaacgtt tgtaggttgc ttagaactgc
    14881 gattcttcag tggagccggt cagcgcggtg actgaagacg tgccgccctg aataatggtc
    14941 gtcactttat cgaagtaacc tgtacccact tcctgctggt gagatacgaa ggtatagcca
    15001 tctttcgcgg cggcaaattc cggctgctgc actttctcaa cgtagtgctt cataccttcg
    15061 ccctgggcat aggcgtttgc cagatcgaac atgttaaacc acatgctgtg gatgcctgcc
    15121 agggtgatga actggaactt gtagcccata tccgacagct gctgctggaa gctggcaata
    15181 gttttgtcgt cgaggttttt ctgccagttg aacgacggcg agcagttata agccagcagt
    15241 ttgcccggat atttcgcgtg gatggcttgt gcaaagcgac gcgccagttc cagatccggc
    15301 gtggaggttt cacaccatac caggtcagca tatggcgcat acgccaggcc acggctgatc
    15361 gcttgttcaa tacctgcatg agtacggaag aagccttcgc tggtacgctc gccggtaata
    15421 aattcgctgt catatgggtc gcaatcggag gtaatcagat ccgccgcatc ggcatcggta
    15481 cgagcaacca gcagggttgg aacgcccgtc acgtcagctg ccagacgcgc cgcgaccagt
    15541 ttctgaatag cttcctgagt tggcactaaa actttgccgc ccatgtgacc gcatttcttc
    15601 actgatgcca gctgatcttc gaagtgaact gccgctgcac cggcttcaat catcgctttc
    15661 atcagttcaa aggcattcag gacaccgcca aaaccggctt ccgcatcggc aacgatcggc
    15721 aggaagtaat cgacatagcg cggatcgccc ggctcaatgc ctgcggacca ttggatctga
    15781 tccgcacggc ggaaggtgtt gttgatccgc tccaccacag ctggcaccga gtttgccgga
    15841 tagagcgact gatccggata catgctggcc gccaggttag cgtccgccgc tacctgccat
    15901 cccgacagat agactgcttc aatacccgct ttcgcctgtt gcagcgcctg accgccagtc
    15961 agtgcaccga ggctgttgat gtagcctttt ttcgactcgc cgtgcagcag acgccacatt
    16021 ttcgccgcac ccagttgcgc cagcgtgcat tcaggattga ctgaaccgcg taatttcacc
    16081 acatcttccg cgctgtacgg gcgagtaatg ccttcccaac gcggttgagt ccactctttc
    16141 tgtaattctt caatttgttg tgtacgggtt ttcatgtgca gatgctccat agttatgtgg
    16201 tggtttacgc taacaggcgg tagcctggca gggtcaggaa atcaattaac tcatcggaag
    16261 tggtgatctg ttccatcaag cgtgcggcat cgtcaaaacg cccctgggag aaacgttctt
    16321 cgcccagttc gctggcaatg actttcatct cttcgcccag catctggcgg aacaaggctt
    16381 tagtcaccgg tttgccattg ctcaacgttt tttgatgatg gatccactgc cagattgagg
    16441 tacgggaaat ttcagccgtc gccgcatctt ccatcaggcc ataaatcggc acacagccat
    16501 tgccagagat ccacgcttcg atgtactgca cagccacgcg aatgttggcg cgcatacctt
    16561 cttcggtgcg ttcaccatca caaggtgcca gcagctgatc ggcagtaatc ggcgcgtctt
    16621 gttcgcgcat cacttcaagc tgatttttac gggagccgag aatgtcgttg aataccgcca
    16681 ttgccgtatc cgcaaggcct gggtgggcaa tccatgtgcc atcgtgaccg ttattagctt
    16741 ccagcgattt atccgctttt actttgttga gcacctggtt attgcgctct tcatctttgc
    16801 tcggaataaa tgccgccata ccgcccatcg caaaagcacc gcgtttatgg caggttttaa
    16861 tcaacaggcg tgagtaagca ttcaggaagg gtttatccat cgtcactgcc tgtctatctg
    16921 gcaggacgcg atcgggatag tttttcagcg ttttgatata actgaagatg taatcccaac
    16981 gaccgcagtt cagaccaaca atatggtcac gcagcgcgtg aaggatttca tccatctgga
    17041 acacggcggg cagcgtttca atcagcaacg tcgccttgat ggtgccgcgc ggcagattaa
    17101 agcgatcttc tgcatagctg aagacttcgc tccaccaggc cgcttcctgc caggactggg
    17161 ttttcggcag atagaaatag ggaccgctgc cctttgccaa cagtgcctga tagttgtgga
    17221 agaaatagag cgcaaaatca aacaggctac cggggattgc ctcaccacgc caggtgacat
    17281 gtttttccgg caagtgcaga ccgcgtaccc gacaaatcaa aaccgctgga ttgggcttga
    17341 gctgataaat tttgcctgct tcattgctat agctgatggt gccgttaacc gcatcgcgca
    17401 ggttaatttg cccatcgatc actttgttcc agtccggggc cagtgaatct tcgaaatcgg
    17461 ccataaagac tttcacattg gcgttgagcg cgttgatcac catcttgcgc tcaaccgggc
    17521 cggtaatctc tacccgacga tcttgtaagt ccgcgggaat accacgaatt ttccagtcag
    17581 catcacgaat ggaagctgtt tccgaaataa aatcaggcaa cgttccgtta tcgatatcct
    17641 gctgctgctg aatgcgcgct gccagaagtt tattgcgttg tggcgtaaaa tgcgtcacca
    17701 gctcagtcag aaattctacc gcttcggcag taagaatttg cttctcctgc tcgccatacg
    17761 gccttatgaa agccagttca tcggttgttg ttgcctgttc agtcatcgtg cagctcctcg
    17821 tcatggatcc gaaaacttcc ccactgtgaa cgaaggattg ttgtgcgctt ttcgttcagc
    17881 acaactaaga ctactcattt aaaatgcaaa atcaaaaaca atttccattt taattaaaaa
    17941 tacttgataa cttattgata acaatatgaa taaattttat tcacctactg aggtgcgttt
    18001 cggaaataaa aaaggcaccc gaaggtgcct gaggtaaggt gctgaatcgc ttaacgatcg
    18061 actatcacag aagattaatc cagcgttgga ttcatgtgcc gtagatcgta tggcgtgatc
    18121 tggtagacgt aatagttgag ccagttggta aacagcaaat taccgtgact acgccagctc
    18181 gctcgcggtt tgttttgcgg atcattgtgc gggaaatagt tatacggtac ttccgggtct
    18241 agtccggctt ccacatcgcg gaaatattcc tgcgccagcg tttgcgcatc atattcggga
    18301 tggcccgtca caaaggcaat gcgcttatct ttgctggcaa acagatatgc atccccttct
    18361 tccgtctctg ccagaatttc cagatcggtg taatcacgaa tcaacgctgc cggaaagtca
    18421 gcatagcgcg aatgcggtgc caggaatgaa tcatcaaagc cacgcgtcag aagcgcatga
    18481 ggatggagaa tatgatgctc gtaaacgcca gagagtttgt cggtgcgagt ttgcttagga
    18541 atgccgtaga ggatatttag cgcggcctgt accgcccagc agacaaacag cgtcgaggtg
    18601 acgtgatctt tcgaccactc cagcacctgt ttgatctgcg gccagtaagc gacatcatta
    18661 aactccacca ggcccagcgg cgcgccggta actatcagac cgtcaaagtt ttgttcctga
    18721 atatcttcaa agttacagta gaagttattc agatgctctg cgggcgtgtt gcgcgattca
    18781 cgggaatcaa tgcgcaacag ctgaatatcg acctgcaaag gtgagtttga aagcaggcgc
    18841 agaaactgat tttcagtttc gatcttcttc ggcatcaggt taaggataag tacctttagc
    18901 ggacgaattt cctgaccaga cgcacgagaa gttgtcatca caaagacgtt ttcttcacgc
    18961 aagaaattga cggcgggtag ctcgtccggc acacgaatcg gcataacctg attacctcac
    19021 tacatacgct tatacgttta gacatccaga tagctgaaga taaccagaaa atttgccaat
    19081 gtcgagtctg catgttgaag gtgagaaagt ttcaaggaaa aggctacgtt agaatataag
    19141 aatgacgaaa aggagagaaa atggttatta gtattcgccg ctcacggcat gaggaagggg
    19201 aggaactcgt tgcgatttgg tgtcgttctg tcgatgccac tcacgatttt ttatcagcag
    19261 agtatcgggc cgagctggag gagctagttc gttccttctt gccggaagcg ccgttgtggg
    19321 tcgcggttaa tgagcgggat cggctggttg ggtttatgtt gttaagtggg cagcatatgg
    19381 atgcgctttt tgtcgatcct gatgcgcgcg gttgtggcgt gggccggatg ctggtggaac
    19441 atgcgctctc gatggcaccg gaactgacaa caaatgttaa tgagcaaaat aagcaggctg
    19501 ttgggttcta taagaagatg ggttttaagg ttacgggacg ctctgaggtg gacgatttgg
    19561 ggaaaccgta tccattgctg aatctggcat atgtggggga ataagctgcc ccctatcgtg
    19621 ctatcgtgcc tgcgtaagct ggagcagacg cgccagcgtc gcagccggcc gttttctgca
    19681 ccagcgcaaa aaggccatcc tgacgga
//
LOCUS       DADXDL010000096        19652 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.096, whole genome shotgun sequence.
ACCESSION   DADXDL010000096 DADXDL010000000
VERSION     DADXDL010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19652)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19652)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19652
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.096"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..835)
                     /gene="rluB"
                     /locus_tag="IRB70_003874"
     CDS             complement(<1..835)
                     /gene="rluB"
                     /locus_tag="IRB70_003874"
                     /EC_number="5.4.99.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(2605) synthase RluB"
                     /protein_id="HBC0633732.1"
                     /translation="MSEKLQKVLARAGHGSRREIESIIEAGRVSVDGKIAKLGDRVEV
                     TPGLKIRIDGHLISVRESAEQICRVLAYYKPEGELCTRNDPEGRPTVFDRLPKLRGAR
                     WIAVGRLDVNTCGLLLFTTDGELANRLMHPSREVEREYAVRVFGQVDDAKLRDLSRGV
                     QLEDGPAAFKTIKFSGGEGINQWYNVTLTEGRNREVRRLWEAVGVQVSRLIRVRYGDI
                     PLPKGLPRGGWTELDLAQTNYLRELVELPPETSSKVAVEKDRRRMKANQIRRAVKRHS
                     QV"
     gene            complement(1046..2935)
                     /locus_tag="IRB70_003875"
     CDS             complement(1046..2935)
                     /locus_tag="IRB70_003875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2207 domain-containing protein"
                     /protein_id="HBC0633733.1"
                     /translation="MAGKFRCILLLIAGLFFSSLSYAKNTEIPSYEEGISLFDVEATL
                     QPDGVLDIKENIHFQARNQQIKHGFYRDLPRLWMQPDGDAALLNYHIVGVTRDGIPEP
                     WHLDWHIGLMSIVVGDKQRFLPQGDYHYQIHYQVKNAFLREGDSDLLIWNVTGNHWPF
                     EIYKTLFSLKLPDIAGNPFSEIDLFTGEEGDTYRNGRILEDGRIESRDPFYREDFTVL
                     YRWPHALLSNAPAPQTTNIFSHLLLPSTSSLLIWFPCLFLVCGWLYLWKRRPQFTPVD
                     VIETDVIPQDYTPGMLRLDAKLVYDDKGFCADIVNLIVKGKIHLEDQYDKNQQILIRV
                     NEGATRNNAVLLPAEQLLLEALFRKGDKVVLTGRRNSVLRKAFLRMQKFYLPRKKSSF
                     YRPDAFLQWGGMAILAVILYGNLSPVGWAGMSLVGDMFIMICWLLPFLFCSLELLFAR
                     DDDKPCVNRVIITLFLPLICSGVAFYSLYINVGDVFFYWYMPAGYFSAVFLTGYLTGM
                     GYIFLPKFTQTGQQSYAHGEAIVNYLARKEAATHSGRRRKGETRKLDYALLGWAVSAN
                     LGREWAARITPSLTAAVRAPEIARSGVLFSLQTHLSCGAYTSLLGRSYSGGGSGAGGG
                     GGSGW"
     gene            complement(2963..3583)
                     /locus_tag="IRB70_003876"
     CDS             complement(2963..3583)
                     /locus_tag="IRB70_003876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005126434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBC0633734.1"
                     /translation="MSQFFYIHPDNPQQRLINQAVEIVRKGGVIVYPTDSGYALGCKI
                     EDKNAMERICRIRQLPDGHNFTLMCRDLSELSTYSFVDNVAFRLMKNNTPGNYTFILK
                     GTKEVPRRLLQEKRKTIGMRVPSNPIAQALLEALGEPMLSTSLMLPGSEFTESDPEEI
                     KDRLEKQVDLIIHGGYLGQKPTTVIDLTDDTPVVVREGVGDVKPFL"
     gene            complement(3580..4461)
                     /gene="yciV"
                     /locus_tag="IRB70_003877"
     CDS             complement(3580..4461)
                     /gene="yciV"
                     /locus_tag="IRB70_003877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-3' exoribonuclease"
                     /protein_id="HBC0633735.1"
                     /translation="MSDTNYAVIYDLHSHTTASDGCLTPEALVHRAVEMRVGTLAITD
                     HDTTAAIAPAREEISRSGLALNLIPGVEISTVWENHEIHIVGLNIDITHPLMCEFLAQ
                     QTERRNQRAQLIAERLEKAQIPGALEGAQRLAQGGAVTRGHFARFLVECGKASSMADV
                     FKKYLARGKTGYVPPQWCTIEQAIDVIHHSGGKAVLAHPGRYNLSAKWLKRLVAHFAE
                     HHGDAMEVAQCQQSPNERTQLATLARQHHLWASQGSDFHQPCPWIELGRKLWLPAGVE
                     GVWQLWEQPQNTTEREL"
     gene            4599..4643
                     /gene="trpL"
                     /locus_tag="IRB70_003878"
     CDS             4599..4643
                     /gene="trpL"
                     /locus_tag="IRB70_003878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trp operon leader peptide"
                     /protein_id="HBC0633736.1"
                     /translation="MKAIFVLKGWWRTS"
     misc_feature    4620..4713
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00513"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Trp leader region; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /db_xref="RFAM:RF00513"
     gene            4735..6297
                     /gene="trpE"
                     /locus_tag="IRB70_003879"
     CDS             4735..6297
                     /gene="trpE"
                     /locus_tag="IRB70_003879"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anthranilate synthase component I"
                     /protein_id="HBC0633737.1"
                     /translation="MQTQKPTLELLTCKGAYRDNPTALFHQLCGDRPATLLLESADID
                     SKDDLKSLLLVDSALRITALGDTVTIQALSGNGEALLALLDNALPAGVENEQSPNCRV
                     LRFPPVSPLLDEDARLCSLSVFDAFRILQNLLNVPKEEREAMFFGGLFSYDIVAGFED
                     LPQLSAENNCPDFCFYLAETLMVIDHQKKSTRIQASLFTPNEEEKQRLTARLNELRQQ
                     LTETAPPLPVVSVPHMLCECNQSDEEFGGVVRSLQKAIRAGEIFQVVPSRRFSLPCPS
                     PLAAYYVLKKSNPSPYMFFMQDNDFTLFGASPESSLKYDATSRQIEIYPIAGTRPRGR
                     RADGSLDRDLDSRIELEMRTDHKELSEHLMLVDLARNDLARICTPGSRYVADLTKVDR
                     YSYVMHLVSRVVGELRHDLDALHAYRACMNMGTLSGAPKVRAMQLIAEAEGRRRGSYG
                     GAVGYFTANGDLDTCIVIRSALVENGIATVQAGAGVVLDSVPQSEADETRNKARAVLR
                     AIATAHHAQETF"
     gene            6297..7892
                     /gene="trpD"
                     /locus_tag="IRB70_003880"
     CDS             6297..7892
                     /gene="trpD"
                     /locus_tag="IRB70_003880"
                     /EC_number="2.4.2.18"
                     /EC_number="4.1.3.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008784940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional anthranilate synthase glutamate
                     amidotransferase component TrpG/anthranilate
                     phosphoribosyltransferase TrpD"
                     /protein_id="HBC0633738.1"
                     /translation="MADILLLDNIDSFTYNLADQLRSNGHNVVIYRNHIPAQTLIERL
                     ATMSNPVLMLSPGPGVPSEAGCMPELLTRLRGKLPIIGICLGHQAIVEAYGGYVGQAG
                     EILHGKASSIEHDGQAMFAGLTNPLPVARYHSLVGSNIPAGLTINAHFNGMVMAVRHD
                     ADRVCGFQFHPESILTTQGARLLEQTLAWAQQKLEPTNTLQPILEKLYQAQTLSQQES
                     HQLFSAVVRGELKPEQLAAALVSMKIRGEHPNEIAGAATALLENAAPFPRPDYLFADI
                     VGTGGDGSNSINISTASAFVAAACGLKVAKHGNRSVSSKSGSSDLLAAFGINLDMNAD
                     KSRQALDELGVCFLFAPKYHTGFRHAMPVRQQLKTRTLFNVLGPLINPAHPPLALIGV
                     YSPELVLPIAETLRVLGYQRAAVVHSGGMDEVSLHAPTIVAELHDGEIKSYQLTAEDF
                     GLTPYHQEQLAGGTPEENRDILTRLLQGKGDAAHEAAVAANVAMLMRLHGHEDLQANA
                     QTVLEVLRSGSAYDRVTALAARG"
     gene            7896..9254
                     /gene="trpCF"
                     /locus_tag="IRB70_003881"
     CDS             7896..9254
                     /gene="trpCF"
                     /locus_tag="IRB70_003881"
                     /EC_number="4.1.1.48"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309861.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional indole-3-glycerol-phosphate
                     synthase TrpC/phosphoribosylanthranilate isomerase TrpF"
                     /protein_id="HBC0633739.1"
                     /translation="MQTVLAKIVADKAIWVEARKQQQPLASFQNEIQPSTRHFYDALQ
                     GARTAFILECKKASPSKGVIRDDFDPARIAAIYKHYASAISVLTDEKYFQGSFDFLPI
                     VSQIAPQPILCKDFIIDPYQIYLARYYQADACLLMLSVLDDEQYRQLAAVAHSLEMGV
                     LTEVSNEEELERAIALGAKVVGINNRDLRDLSIDLNRTRELAPKLGHNVTVISESGIN
                     TYAQVRELSHFANGFLIGSALMAHDDLNAAVRRVLLGENKVCGLTRGQDAKAAYDAGA
                     IYGGLIFVATSPRCVNVEQAQEVMAAAPLQYVGVFRNHDIADVVDKAKVLSLAAVQLH
                     GNEDQLYIDTLREALPAHVAIWKALSVGETLPARDFQHIDKYVFDNGQGGSGQRFDWS
                     LLNGQSLGNVLLAGGLGADNCVEAAQTGCAGLDFNSAVESQPGIKDARLLASVFQTLR
                     AY"
     gene            9266..10459
                     /gene="trpB"
                     /locus_tag="IRB70_003882"
     CDS             9266..10459
                     /gene="trpB"
                     /locus_tag="IRB70_003882"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit beta"
                     /protein_id="HBC0633740.1"
                     /translation="MTTLLNPYFGEFGGMYVPQILMPALRQLEEAFVSAQKDPEFQAQ
                     FNDLLKNYAGRPTALTKCQNITAGTNTTLYLKREDLLHGGAHKTNQVLGQALLAKRMG
                     KTEIIAETGAGQHGVASALASALLGLKCRIYMGAKDVERQSPNVFRMRLMGAEVIPVH
                     SGSATLKDACNEALRDWSGSYETAHYMLGTAAGPHPYPTIVREFQRVIGEETKAQILE
                     REGRLPDAVIACVGGGSNAIGMFADFINETNVGLIGVEPGGHGIETGEHGAPLKHGRV
                     GIYFGMKAPMMQTEDGQIEESYSISAGLDFPSVGPQHAYLNSTGRADYVSITDDEALE
                     AFKTLCLHEGIIPALESSHALAHALKMMRENPEKEQLLVVNLSGRGDKDIFTVHDILK
                     ARGEI"
     gene            10459..11265
                     /gene="trpA"
                     /locus_tag="IRB70_003883"
     CDS             10459..11265
                     /gene="trpA"
                     /locus_tag="IRB70_003883"
                     /EC_number="4.2.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan synthase subunit alpha"
                     /protein_id="HBC0633741.1"
                     /translation="MERYESLFAQLKERKEGAFVPFVTLGDPGIEQSLRIIDTLIEAG
                     ADALELGIPFSDPLADGPTIQNATLRAFAAGVTPAQCFEMLALIRQKHPTIPIGLLMY
                     ANLVFNKGIDEFYAECEKVGVDSVLVADVPVEESAPFRQAALRHNVAPIFICPPNADD
                     DLLRQIASYGRGYTYLLSRAGVTGAENRAALPLNHLVTKLKEYNAAPPLQGFGISAPD
                     QVKAAIDAGAAGAISGSAIVKIIEQHINEPEKMLAALKAFVQPMKAATRS"
     gene            11656..11835
                     /locus_tag="IRB70_003884"
     CDS             11656..11835
                     /locus_tag="IRB70_003884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309858.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="general stress protein"
                     /protein_id="HBC0633742.1"
                     /translation="MAEHRGGSGNFAEDREKASDAGRKGGQHSGGNFKNDPQRASEAG
                     KKGGQQSGGNKSGKS"
     gene            11921..12421
                     /locus_tag="IRB70_003885"
     CDS             11921..12421
                     /locus_tag="IRB70_003885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
                     /protein_id="HBC0633743.1"
                     /translation="MNMKTIEDVFIHLLSDTYSAEKQLTRALAKLARATSNEKLSQAF
                     HAHLEETHGQIERIDQVVESESNLKIKRMKCVAMEGLIEEANEVIESTEKNEVRDAAL
                     IAAAQKVEHYEIASYGTLATLAEQLGYRKAAKLLKETLEEEKATDIKLTDLALNNVNK
                     KAENKA"
     gene            12467..12972
                     /locus_tag="IRB70_003886"
                     /pseudo
     CDS             12467..12972
                     /locus_tag="IRB70_003886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309856.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ferritin-like domain-containing protein"
     gene            complement(13032..13157)
                     /locus_tag="IRB70_003887"
                     /pseudo
     CDS             complement(13032..13157)
                     /locus_tag="IRB70_003887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415772.1"
                     /note="receptor for colicin S4; incomplete; partial in the
                     middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein OmpW"
     gene            complement(13461..13631)
                     /locus_tag="IRB70_003888"
     CDS             complement(13461..13631)
                     /locus_tag="IRB70_003888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001710241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633744.1"
                     /translation="MVRLPPVVMSAKSATARTTIAREDAEDHQVKLSAQKLEELLASM
                     VKDEVDRNDGIY"
     gene            complement(13746..14015)
                     /locus_tag="IRB70_003889"
     CDS             complement(13746..14015)
                     /locus_tag="IRB70_003889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000937495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBC0633745.1"
                     /translation="MLPQHSDIEIAWYASIQQEPNGWKIVTTQFYIQEFSEYIAPLQD
                     AVDLEIATEEERSLLEAWNKYRVLLNRVDTSTAPDIEWPANPVRE"
     gene            14072..14740
                     /locus_tag="IRB70_003890"
     CDS             14072..14740
                     /locus_tag="IRB70_003890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBC0633746.1"
                     /translation="MVKSMKKNTDDGAKIYTPLTLKLYDWWVLGVSNRLAWGCPTKEH
                     LLPHFLEHVGNNHLDIGVGTGFYLTHVPESSLISLMDLNEASLNAASTRAGESKIKHK
                     ISHDVFEPYPAALHGQFDSISMFYLLHCLPGNISTKSCVIRNAAQALTDDGTLYGATI
                     LGDGVVHNSFGQKLMRIYNQKGIFSNTKDSEEGLTHILSEHFENVKTKVQGTVVMFSA
                     SGKK"
     gene            complement(14795..15379)
                     /locus_tag="IRB70_003891"
     CDS             complement(14795..15379)
                     /locus_tag="IRB70_003891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000885581.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
                     /protein_id="HBC0633747.1"
                     /translation="MAFRMSEQARTIKIYNLLAGTNEFIGEGDAYIPPHTGLPANSTD
                     IAPPDIPAGFVAVFNSDEASWHLVEDHRGKTVYDVASGDELFISELGPLPENVTWLSP
                     EGEFQKWNGTAWVKDTEAEKLFRIREAEETKNNLMQVASEHIAPLQDAADLEIATEEE
                     TSLLEAWKKYRVLLNRVDTSTAPDIEWPVNPVRE"
     gene            complement(15379..18384)
                     /locus_tag="IRB70_003892"
     CDS             complement(15379..18384)
                     /locus_tag="IRB70_003892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001565308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HBC0633748.1"
                     /translation="MTVKISGVLKDGTGKPVQNCTIVLKARRTSSTVVVNTVASENPD
                     EAGRYSMDVEHGQYSVTLLVEGFPPSHAGTITVYEGSRPGTLNDFLGAMTEDDVRPEA
                     LRRFEQMVEEVSRNASAVAQNTAAAKKSASDASASATDAAASARAASTSAGQAASSAQ
                     SASSSAGTASTKAREAAKSAAAAESSKSAAATSASAAKTSETNAAASQKSAATSASTA
                     TTKASEAATSARGAAASKEAAKSSETNASSSASSAASSATAAGNSAKAAKTSETNAKS
                     SETAAGQSASAAAGSKTAAALSASAASTSAGQASASATAAGKSAESAASSASTATTKA
                     GKATEQATAAARSASAAKTSETNAKTSADNAASSKAAAASSASSAASSASSASASKDE
                     ATRQASAAKGSATTATTKASEAAGSATAASQSKVAAESAATRAETAAKRAEDIASAVA
                     LEDASTTKKGIVQLSSATNSTSEKLAATPKAVKTVKDSSVQKTGDTMGGQLKISTINA
                     LRIFNQAFGLIFRRSEDHLHLIPTNEGEGENGDIGSLRPFSINLRSGLVSIGNGLKVG
                     GSVTGNLTGNADTATKIKTARKIGGVAFDGSADINLPGVNATGNQNTTGNAATATKLQ
                     AARTINGVSFDGSANITLTPSNIGALALTGGTLSGGLTAAGEVISRSANGLRIAYGNY
                     GFFIRNDGSNTYFMLTDSGNSLGTHNSLRPFIISNHTGNVTIATKLNASGGITGSLSG
                     NASTATKLQTARTINGVKFDGSANIEAFPPGVPLPWPSDTPPAGYAIMQGQTFDKAAY
                     PKLAIAYPSGVIPDMRGWTIKGKPASGRAVLSQEQDGIKSHTHSASASSTDLGTKTTS
                     SFDYGTKSTNNTGAHTHSLSGSTGSAGVHTHGNGIRWPGGGGSALAFYDGGGFTYVQN
                     SQYQVSPETSSYRSYYQRIQTQSAGAHTHSLSGTAASSGAHAHTVGIGAHTHSVAIGS
                     HGHTITVNAAGNAENTVKNIAFNYIVRLA"
     gene            complement(18536..19135)
                     /locus_tag="IRB70_003893"
     CDS             complement(18536..19135)
                     /locus_tag="IRB70_003893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ail/Lom family protein"
                     /protein_id="HBC0633749.1"
                     /translation="MRKLCAVILSAVVWQVAAATPASAAEHQSTLSAGYLHASTNVPG
                     SDDLNGINVKYRYEFTDALGLITSFSYANAEDEQKTRYSDTRWHEDSVRNRWFSVMAG
                     PSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKTHDVLTGSDDGRHSNTSLAW
                     GAGVQFNPTESVTIDLAYEGSGSGDWRTDAFIVGIGYRF"
     gene            complement(19203..>19652)
                     /locus_tag="IRB70_003894"
     CDS             complement(19203..>19652)
                     /locus_tag="IRB70_003894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633750.1"
                     /translation="RVLGKLSANQIEGDLVKTVGKAFPRDSRAPERWPSGTITVRVYD
                     DQPFDRQIVIPAVAFSGAKHEKEHTDIYSSCRLIVRKNGAEIYNRTALDNTLIYSGVI
                     DMPAGHGHMTLEFSVSAWLVNNWYPTASISDLLVVVMKKATAGITIS"
BASE COUNT         4892 a         5088 c         4753 g         4919 t
ORIGIN      
        1 tcacctgact gtgacgtttc accgcacgac gaatctgatt cgccttcatg cgacgacggt
       61 ctttttctac agcgacttta gagctggttt ctggcggtag ctccaccagt tcgcgcagat
      121 agttagtctg ggcgaggtcc agctccgtcc agccaccgcg tggcagacct tttggcagtg
      181 ggatatcacc gtaacgaaca cggatcaggc ggctcacctg cacaccaacc gcttcccaaa
      241 gacgacgaac ttcacggtta cggccttcgg tcagagtaac gttgtaccac tggttgatcc
      301 cttcgccgcc gctgaacttg atggttttaa aggctgccgg accatcttcc aactgcacgc
      361 cacgactcaa atcacgcagt ttcgcgtcgt caacctgacc aaatacacgc acggcatatt
      421 cacgttcaac ttcacggctt gggtgcatta aacggtttgc cagttcacca tcggtggtga
      481 acagcagcag accacaggtg ttaacgtcca ggcgacccac ggcaatccag cgtgcgccac
      541 gcagttttgg cagacggtca aacaccgttg gacgtccttc cggatcgtta cgggtacaca
      601 actcaccttc cggtttgtaa taggccagaa cgcgacaaat ttgttcagcg gactcacgta
      661 ccgaaatcag gtgaccatcg atacggattt tcaatccagg ggtaacttca acgcgatcgc
      721 cgagtttagc aattttgcca tcaacactca cacgaccggc ttcaataata gattcgattt
      781 cacggcgaga gccgtggccg gcacgcgcca gcactttctg tagcttttcg ctcatagagc
      841 ttccttttgg tgtcgccttc ccaggcgtct gatatgcttt tgtgcaacag tgagtcagaa
      901 cttacatctg actcactgat agtaaagtct gtttgaactc ttcaggcctt aagtaaacga
      961 ctcgacgttt atcggcctgg ctttgaggcg caacatacta cactatcttt atggttaaag
     1021 cttgtttcga ttaatatcag cttgattacc agccactacc gcctccgcca ccagcgccag
     1081 aaccaccacc ggaatagctc cgccccaaca aactggtata ggccccgcaa ctcaggtgcg
     1141 tctgtaatga gaataaaacg ccactacggg caatttccgg ggcgcgaaca gccgctgtga
     1201 gtgacggcgt gatacgtgct gcccattctc tgccaaggtt tgccgagact gcccaaccta
     1261 gcaacgcgta atccagtttc cgtgtttccc ctttccgccg acgcccactg tgtgttgctg
     1321 cctctttacg cgcaagatag ttaacgatag cttcaccgtg ggcataactt tgctgcccag
     1381 tttgggtaaa ctttggcaga aaaatatacc ccatgccagt gagatagccg gtcaggaaaa
     1441 cagcgctaaa ataacccgct ggcatatacc agtaaaagaa tacatctccg acattgatat
     1501 agagagagta aaaggccacg cctgaacaaa tcagcggtaa aaacaaagtg atgattacac
     1561 gattaacgca aggcttgtca tcatcgcggg caaacaaaag ctcaagggaa caaaataaga
     1621 aaggaagaag ccagcagatc ataataaaca tatcgccaac cagactcatt cctgcccagc
     1681 ctacgggact caggttaccg tagagaatga ccgccaatat tgccattccg ccccattgca
     1741 aaaacgcatc aggtcggtaa aacgaagact ttttacgcgg cagataaaat ttctgcatcc
     1801 gtaaaaatgc cttgcgtaag acgctgttgc gtctacccgt aagaacgacc ttatcgcctt
     1861 tacgaaataa cgcttccagt aataactgct ctgcgggcag taataccgca ttatttctgg
     1921 tcgcgccttc attaacacga atcaggattt gctggttctt atcatactga tcttccagat
     1981 gaatttttcc tttcacaatc agatttacga tatcggcaca aaaaccttta tcgtcgtaaa
     2041 ccagcttcgc atcgagacgt aacatgccgg gtgtgtaatc ttgcggaatg acatcggttt
     2101 caatcacatc taccggcgta aattgcggcc tgcgcttcca gagatataac catccacaaa
     2161 ccaggaatag acaaggaaac caaattaaca acgatgacgt ggagggtaaa agaagatggc
     2221 tgaaaatatt cgtcgtttgt ggagccgggg cattgctaag taaagcgtga ggccagcggt
     2281 agagtaccgt gaaatcttca cgataaaacg gatcgcggga ttcaattctt ccgtcctcaa
     2341 ggatgcggcc atttcgatat gtgtcgccct cttctccagt aaagagatcg atttcgctaa
     2401 atggattacc cgcaatatca ggcaacttga gtgaaaatag ggttttataa atttcaaacg
     2461 gccagtggtt accggtcacg ttccagatta gcagatcaga atccccttca cgcaggaaag
     2521 catttttaac ctgataatga atttgataat gatagtcgcc ttgaggcaag aaacgttgtt
     2581 tatcgcccac gacaatactc attaacccga tatgccagtc aagatgccag ggttcaggaa
     2641 taccatcacg ggtgacgcca acaatatgat agttcagcag tgcagcgtcc ccatcaggct
     2701 gcatccagag tcgtggtaaa tcacgataaa atccgtgctt aatctgctga tttcgcgcct
     2761 gaaaatgaat attttctttg atgtcgagca ccccatccgg ttgcagagtg gcttcaacat
     2821 caaagagcga gatcccttct tcataagaag ggatctccgt gtttttcgca taactcaacg
     2881 aagagaaaaa aagccctgct atcaacagca aaatgcagcg aaacttccct gccatagtct
     2941 tccatccgtg gaacgcaatt tgttataaga aaggcttcac atcacctacg ccttcacgca
     3001 ccacgaccgg cgtatcatca gtaagatcaa taaccgttgt tggtttctgc ccgagatagc
     3061 cgccgtgaat aatcaaatct acctgttttt ccagacggtc tttaatttct tcgggatcgg
     3121 attcggtaaa ttcgctgcct ggcagcatta gcgaagtgga aagcatcggt tcgcccagtg
     3181 cttcaagcaa cgcctgcgca atcgggttag acggcacacg cataccgatg gttttgcgtt
     3241 tttcctgcaa cagacggcgt ggcacttcct tcgtcccctt caggatgaag gtatagttgc
     3301 ccggcgtgtt gtttttcatt aaacgaaacg caacgttatc gacaaatgaa taggtcgaga
     3361 gttcagaaag atcgcgacac atcagggtaa agttgtgacc gtccggcagc tggcgaatac
     3421 gacaaatacg ctccatcgcg tttttatctt caattttaca gccgagcgca tagccggaat
     3481 cagttggata aacaatcacc ccgcctttac gcacgatctc caccgcctgg ttgatcagac
     3541 gttgctgcgg gttatcagga tgaatataaa aaaactggct cataattccc tctctgtggt
     3601 gttctgcggc tgttcccata gctgccagac gccttcaacg cctgcgggca gccagagttt
     3661 acgacccagt tcgatccacg ggcatggctg atgaaaatca gatccttgtg atgcccataa
     3721 atgatgctga cgcgcaagtg tcgccagctg ggtgcgttca ttgggcgatt gctggcactg
     3781 cgcgacttcc atcgcgtcgc cgtggtgttc ggcaaaatgc gcaaccaatc ttttcagcca
     3841 tttagcacta agattgtacc gcccaggatg agctagcacc gccttaccgc cagaatgatg
     3901 aatgacatca atagcttgtt ctattgtaca ccactgtggc ggaacgtatc cggttttccc
     3961 gcgcgccaga tactttttaa agacatccgc cattgaactg gcttttccgc actccacaag
     4021 gaaacgagca aaatgaccgc gcgtcaccgc accgccctgc gccagtcgtt gcgcgccttc
     4081 cagtgcccca ggtatttgcg ctttttcaag tctttcggca atcagctgcg cccgctgatt
     4141 gcgccgttct gtctgctgcg cgaggaactc acacattagc ggatgagtaa tatcaatatt
     4201 cagcccgaca atatgaattt catgattttc ccagaccgtg gaaatttcca caccaggaat
     4261 aagattcagc gccagtcccg aacgtgaaat ttcctctctt gctggtgcaa ttgcagctgt
     4321 ggtgtcatgg tcggtgatcg ccagggtgcc gacgcgcatc tcgactgcac ggtgcaccaa
     4381 tgcttctggc gtcaggcagc catcggaagc tgtggtatgg ctgtgcaggt cgtaaatcac
     4441 tgcgtaattc gtgtcgctca aggcgcactc ccgttctgga taatgttttt tgcgccgaca
     4501 tcataacggt tctggcaaat attctgaaat gagctgttga caattaatca ccgaactagt
     4561 taactagtac gcaagttcac gtaaaaaggg tatcgacaat gaaagcaatt ttcgtactga
     4621 aaggttggtg gcgcacttcc tgaaacgggc agtgtattca ccatgcgtaa agcaatcaga
     4681 tacccagccc gcctaatgag cgggcttttt tttgaacaaa attagagaat aacaatgcaa
     4741 acacaaaaac cgactctcga actgctaact tgcaaaggcg cttatcgcga caacccgact
     4801 gcgctttttc accagttgtg tggggatcgt ccggcaacgc tgctgctgga atccgcagat
     4861 atcgacagca aagatgattt aaaaagtcta ttgctagtgg acagtgcgct gcgcattaca
     4921 gcattaggtg acactgtcac tattcaggca ctttccggca atggcgaagc tctgctggca
     4981 ttactggata acgccctgcc tgcgggtgtg gaaaatgaac aatcaccaaa ctgccgcgtg
     5041 ctgcgcttcc cccctgtcag tccattgctg gatgaagacg cccgcttatg ctccctttcg
     5101 gtttttgacg ctttccgcat attgcagaat ctgttgaatg taccgaagga agaacgagaa
     5161 gcaatgttct tcggcggcct gttctcttat gacattgtgg cgggatttga agatttaccg
     5221 caattgtcag cggaaaataa ctgccctgat ttctgttttt atctcgctga aacgctgatg
     5281 gtgattgacc atcagaagaa aagcacccgc attcaggcca gcctgtttac tccaaatgaa
     5341 gaagaaaaac aacgtctcac tgctcgcctg aacgaacttc gccagcaact gaccgaaacc
     5401 gcgccaccgc tgccggtagt ttccgtgccg catatgcttt gtgaatgtaa tcagagcgat
     5461 gaagagttcg gtggcgtagt gcgttcgttg caaaaagcga ttcgcgccgg agaaattttc
     5521 caggtggtgc catctcgccg tttctctctg ccctgcccgt caccgctggc ggcctattac
     5581 gtgctgaaaa agagtaatcc cagcccgtac atgtttttta tgcaggataa tgatttcacc
     5641 ctgtttggcg cgtcgccgga aagttcgctc aagtatgacg ccaccagccg ccagattgag
     5701 atttacccga ttgccggaac acgtccacgc ggtcgtcgtg ccgatggttc actggacaga
     5761 gacctcgaca gccgcatcga actggagatg cgtaccgatc ataaagagct ttctgaacat
     5821 ctgatgctgg tggatctcgc ccgtaatgac ctggcacgca tttgcacacc cggcagccgc
     5881 tacgtcgccg atctcaccaa agtagaccgt tactcttacg tgatgcacct ggtctcccgc
     5941 gttgtcggtg agctgcgcca cgatctcgac gccctgcacg cttaccgcgc ctgtatgaat
     6001 atggggacgt taagcggtgc gccgaaagta cgcgctatgc agttaattgc cgaagcagaa
     6061 ggtcgtcgcc gcggcagcta cggcggcgcg gtaggttatt tcaccgcaaa tggcgatctc
     6121 gacacctgca ttgtgatccg ctcggcgctc gtggaaaacg gtatcgccac cgtgcaagcc
     6181 ggtgctggcg tagtccttga ttctgttccg cagtcggaag ccgacgaaac ccgtaataaa
     6241 gcccgcgctg tactgcgcgc tattgccacc gcgcatcatg cacaggagac tttctgatgg
     6301 ctgacattct gctactcgat aatatcgatt cttttactta caacctggca gatcagttgc
     6361 gcagcaatgg gcataacgtg gtgatttacc gcaaccatat tccggcgcag accttaattg
     6421 aacgcctggc gacgatgagc aatccggtgc tgatgctctc tcctggcccc ggtgtgccga
     6481 gcgaagccgg ttgtatgccg gaactcctca cccgcctgcg cggcaagctg ccaattattg
     6541 gcatttgcct cggtcatcag gcgattgtcg aagcttacgg gggctatgtc ggtcaggcgg
     6601 gcgaaattct tcacggtaaa gcgtcgagca ttgaacatga cggtcaggcg atgtttgccg
     6661 gattaacaaa cccgctgcca gtggcgcgtt atcactcgct ggttggcagt aatattccgg
     6721 ccggtttaac catcaacgcc cattttaatg gcatggtgat ggcggtgcgt catgatgcgg
     6781 atcgcgtttg tggattccag ttccatccgg aatccattct tactacccag ggcgctcgcc
     6841 tgctggaaca aacgctggcc tgggcgcagc agaaactaga gccaaccaac acgctgcaac
     6901 cgattctgga aaaactgtat caggcacaga cgcttagcca acaagaaagc caccagctgt
     6961 tttcagcggt ggtacgtggc gagctgaagc cggaacaact ggcggcggcg ctggtgagca
     7021 tgaaaattcg cggtgagcac ccgaacgaga tcgccggggc agcaaccgcg ctactggaaa
     7081 acgccgcgcc gttcccacgc cctgattatc tgtttgccga tatcgtcggc accggcggtg
     7141 acggcagtaa cagcatcaat atttctaccg ccagtgcgtt tgtcgccgcg gcctgtgggc
     7201 tgaaagtggc gaaacacggc aaccgtagcg tctccagtaa atccggctcg tcggatctgc
     7261 tggcggcgtt cggtattaat cttgatatga acgccgataa atcgcgccag gcgctggatg
     7321 agttaggcgt ctgtttcctc tttgcgccga aatatcacac cggattccgc catgcgatgc
     7381 cggttcgcca gcaactgaaa acccgcactc tgttcaatgt gctggggcca ttgattaacc
     7441 cggcgcatcc gccgctggcg ctaattggtg tttatagtcc ggaactggtg ctgccgattg
     7501 ccgaaacctt gcgcgtgctg gggtatcaac gcgcggcggt ggtgcacagc ggcgggatgg
     7561 atgaagtttc attacacgcg ccgacaatcg ttgccgaact gcatgacggc gaaattaaga
     7621 gctatcaatt gaccgctgaa gattttggcc tgacacccta ccaccaggag caactggcag
     7681 gcggaacacc ggaagaaaac cgtgacattt taacacgctt gttacaaggt aaaggcgacg
     7741 ccgctcacga agcagccgtc gcggcgaatg tcgccatgtt aatgcgcctg catggccatg
     7801 aagatctgca agccaatgcg caaaccgttc ttgaggtact gcgcagtggt tccgcttacg
     7861 acagagtcac cgcactggcg gcacgagggt aaataatgca aaccgtttta gcgaaaatcg
     7921 tcgcagacaa ggcgatttgg gtagaagccc gcaaacagca gcaaccgctg gccagttttc
     7981 agaatgagat tcagccgagc acgcgacatt tttatgatgc gctacagggt gcacgcacgg
     8041 cgtttattct ggagtgcaaa aaagcgtcgc cgtcaaaagg cgtgatccgt gatgatttcg
     8101 atccggcacg cattgctgcc atttataaac attacgcttc ggcaatttca gtgctgactg
     8161 atgagaaata ttttcagggg agctttgatt tcctccctat cgtcagccaa atcgccccgc
     8221 agccgatttt atgtaaagac ttcattatcg atccttacca gatctatctg gcgcgctatt
     8281 accaggctga tgcctgttta ttaatgcttt cagtactgga tgacgaacaa tatcgccagc
     8341 ttgctgctgt cgcccacagt ctggagatgg gtgtgctgac tgaagtcagt aatgaagagg
     8401 aactggagcg cgccattgca ttgggggcaa aggtcgttgg catcaacaac cgcgatctgc
     8461 gtgatttgtc gattgatctc aaccgtaccc gcgagcttgc gccgaagctt gggcacaacg
     8521 tgacggtaat cagcgaatcc ggcatcaata cttacgccca ggtgcgcgag ttaagccact
     8581 tcgctaacgg ttttctgatt ggttcggcgt tgatggccca tgacgatttg aacgccgccg
     8641 tgcgccgggt gttgctgggt gagaataaag tgtgtggcct gacgcgtggg caagatgcta
     8701 aagcagctta tgacgcgggc gcgatttacg gtgggttgat ttttgttgcg acatcaccgc
     8761 gttgcgtcaa cgttgaacag gcgcaggaag tgatggctgc ggcaccgttg cagtatgttg
     8821 gcgtgttccg caatcacgat attgccgatg tggtggacaa agctaaggtg ttatcgctgg
     8881 cggcagtgca actgcatggt aatgaagatc agctgtatat cgacactctg cgtgaggctc
     8941 tgccagcaca cgtcgccatc tggaaggctt taagtgtcgg tgaaactctt cccgcgcgcg
     9001 attttcagca catcgataaa tatgtattcg acaacggtca gggcgggagc ggacaacgtt
     9061 tcgactggtc actgttaaac ggtcaatcgc ttggcaacgt tctgctggcg gggggcttag
     9121 gcgcagataa ctgcgtggaa gcggcacaaa ccggctgcgc cggacttgat tttaattctg
     9181 ctgtagagtc gcaaccgggc atcaaagacg cacgtctttt ggcctcggtt ttccagacgc
     9241 tgcgcgcata ttaaggaaag gaacaatgac aacattactt aacccctatt ttggtgagtt
     9301 tggcggcatg tacgtgccac aaatcctgat gcctgctctg cgccagctgg aagaagcttt
     9361 tgtcagtgcg caaaaagatc ctgaatttca ggctcagttc aacgacctgc tgaaaaacta
     9421 tgccgggcgt ccaaccgcgc tgaccaaatg ccagaacatt acagccggga cgaacaccac
     9481 gctgtatctg aagcgcgaag atttgctgca cggcggcgcg cataaaacta accaggtgct
     9541 gggacaggcg ttgctggcga agcggatggg taaaacggaa atcatcgccg aaaccggagc
     9601 cggtcagcat ggcgtggcgt cggcccttgc cagcgccctg ctcggcctga aatgccgtat
     9661 ttatatgggt gccaaagacg ttgaacgcca gtcgccaaac gtttttcgta tgcgcttaat
     9721 gggtgcggaa gtgatcccgg tacatagcgg ttccgcgacg ctgaaagatg cctgtaacga
     9781 ggcgctgcgc gactggtccg gcagttatga aaccgcgcac tatatgctgg gcaccgcagc
     9841 tggcccacat ccttatccga ccattgtccg tgagtttcag cgagtgattg gcgaagaaac
     9901 caaagcacag attctggaaa gagaaggtcg cctgccggat gcggttatcg cctgtgttgg
     9961 cggcggttcg aatgccatcg gcatgtttgc agatttcatc aacgaaacca acgtcggcct
    10021 gattggtgtg gagcctggcg gtcacggtat cgaaaccggc gagcacggcg caccgttaaa
    10081 acatggtcgc gtgggcatct atttcggtat gaaagcgccg atgatgcaaa ccgaagacgg
    10141 gcagattgaa gaatcttact ccatttctgc cggactggat ttcccgtctg tcggcccgca
    10201 acacgcgtat cttaacagca ctggacgcgc tgattacgtg tcaattaccg atgatgaagc
    10261 actggaagcc ttcaaaacgc tttgcctgca tgaagggatc atcccggcgc tggaatcctc
    10321 ccacgccctg gcccatgcgc tgaaaatgat gcgcgaaaat ccggaaaaag agcagctact
    10381 ggtggttaac ctttccggtc gcggcgataa agacatcttc accgttcacg atattttgaa
    10441 agcacgaggg gaaatctgat ggaacgctac gaatctctgt ttgcccagtt gaaggagcgc
    10501 aaagaaggcg cattcgttcc tttcgtcacc ctcggtgatc cgggcattga gcagtcgttg
    10561 agaattatcg atacgctaat tgaagccggt gctgacgcgc tggagttagg catccccttc
    10621 tccgacccac tggcggatgg cccgacgatt caaaacgcca cactgcgtgc ttttgcggcg
    10681 ggagtaaccc cggcgcagtg ctttgagatg ctggcactca ttcgccagaa gcacccgacc
    10741 attcccatcg gccttttgat gtatgccaac ctggtgttta acaaaggcat tgatgagttt
    10801 tatgccgagt gcgagaaagt cggcgtcgat tcggtgctgg ttgccgatgt gcccgtggaa
    10861 gagtccgcgc ccttccgcca ggccgcgttg cgtcataatg tcgcacctat ctttatttgc
    10921 ccgccgaatg ccgacgatga tttgctgcgc cagatagcct cctacggtcg tggatacacc
    10981 tatttattgt cacgtgcggg cgtgaccggc gcagaaaacc gcgccgcgtt acccctcaat
    11041 catctggtca cgaagctgaa agaatacaat gctgcgcctc cattgcaggg atttggtatt
    11101 tccgccccgg atcaggtaaa agcagcgatt gatgcaggag ctgcgggcgc gatttctggt
    11161 tcggccatcg ttaaaatcat cgagcaacat attaatgagc cagagaaaat gctggcggca
    11221 ctgaaagctt ttgtacaacc gatgaaagcg gcgacgcgca gttaatccca cagccgccag
    11281 ttccgctggc ggcattttaa ctttctttaa cgaagccgga aaaatcctaa attcatttaa
    11341 tatttatctt tctaccgttt cgtttacccc tgtcgaacgt caacttacgt catttttccg
    11401 cccaacagta atataatcaa acaaattaat cccgcaacat aacaccagta aaatcaataa
    11461 ttttctctaa gtcacttatt cctcaggcta ttgttaatat atccagaatg ttcctcaaaa
    11521 tatattttcc ctcttttttc tcgttacgct taatttgact aatactcatt tgcgactaat
    11581 tttaatgagt gtcgacacac aacactcata ttaatcaaac aatgcaacgc aacgcaacgc
    11641 aacgggagaa ataacatggc cgaacatcgt ggtggttcag gaaatttcgc cgaagaccgt
    11701 gagaaggcat ccgacgcagg ccgtaaaggc ggtcagcata gcggcggtaa ttttaaaaat
    11761 gatccgcaac gcgcatctga agcgggtaaa aaaggcggtc aacaaagcgg tggtaataaa
    11821 tcaggaaaat cctgattcac cgttcattat taatatcagc tgataaagat aattgcatct
    11881 gcgggccgta tggctcgcag tgatttcact ggagaaaaat atgaatatga agaccattga
    11941 agatgtattt attcacctgc tttcagacac ctacagtgca gaaaaacaat taacacgtgc
    12001 actggcaaaa ctcgctagag caacatcaaa cgaaaaatta agtcaggctt ttcatgcgca
    12061 cctcgaggaa acacatggac agattgaacg tattgatcaa gttgtggaat cagaatcgaa
    12121 tctgaaaatt aagcgcatga aatgtgtggc aatggaaggt cttattgaag aagctaatga
    12181 ggtcatcgaa agtaccgaga aaaacgaagt gcgtgatgcc gcactgattg ccgcagcaca
    12241 gaaagtcgag cattatgaga ttgccagtta cgggacatta gcgacgctgg ctgaacaatt
    12301 aggttaccgt aaagcagcta agcttctgaa agaaactctt gaagaagaaa aggccaccga
    12361 catcaaacta actgatctgg cccttaataa cgtaaataag aaagccgaaa ataaagcctg
    12421 aaatatgaac tttaactttt agtcatttta taaagaggac attttcatga atcgtattga
    12481 acattatcat gactggttac gtgacgccca cgcaatggaa aagcaagccg aatctatgct
    12541 ttaatccatg gccagccgta tagataatta tcctgaacta cgcgctcgta ttgaacaaca
    12601 tcttattgaa accaaaaacc gattgttcaa ctggaaacta ttcttgatcg taatgacatt
    12661 tcacgttcag tcattaaaga ttccatgagt aaaatggctg cgcttgggca gtcaatcggt
    12721 ggtatattcc cttctgatga aatagtcaaa ggctctatta gcggatatgt cttcgagcaa
    12781 tttgaaatcg cctgttacac ctcactctta gcagcagcaa aaaatgccgg tgatacagct
    12841 tcaattccaa ccatcgaagc gattttaaat gaggaaaagc aaatggccga ctggctgatt
    12901 cagcatattc cgcaaacaac tgagaaattt ttaattcgct ctgaaactga tggcgtagaa
    12961 gcgaagaaat aatacccttt ataccatgtc cttattgacc ccgtatatta cggggtcgtt
    13021 tttgtgcgga attaaaaacg atatcctgct gagaacataa acacccacgg atcgaggcgt
    13081 acgctatcgt gttgctgtgc accgcccagt ttataattgg cggtggtatc gatatccatg
    13141 taccacactg gtaggtttca aaaaacacaa taaccaattg tatttgaagc aaaaaacaag
    13201 actttgagat gtttttttgt accttttttt tatgttttta actgtctgat tttattgaaa
    13261 tcttttttag ttttgcagaa ggaatttttt acttgattgt aactttttcg tttttttggg
    13321 gctaattgac gcgcaatgct gggcggggag cgcacagcca aaaaaaccga aattgaccgc
    13381 taattactgc caatcatcat cgctctgatt gagcgtaaat cattcaggtt attcagttct
    13441 tccttctgct ctcgctgacg tcaataaatc ccatcattgc gatcaacctc atccttaacc
    13501 attgatgcga gcagttcttc cagtttctgc gctgatagct ttacctggtg atcttcagca
    13561 tcttcccggg ctattgtggt tcgcgcagtg gctgattttg ctgacatcac cacagggggc
    13621 agacggacca ttgaaccatg gcctccggaa caaataaggg caaaaataac aaccactatc
    13681 gaaagctcac aaactaaccg cagcacgttc ctgcatacga cgtgtctgcg gcataatccc
    13741 aatgattact ccctgacagg atttgcaggc cactcaatat caggtgcagt tgatgtatca
    13801 acacgattca acaatacccg atatttattc catgcctcca gcaacgatct ttcttcctcc
    13861 gttgcgattt ccagatctac agcatcctgc agtggcgcaa tatactcact gaattcctgg
    13921 atgtagaact gtgtggtgac gatcttccag ccattcggct cctgctgtat cgaagcatac
    13981 caggctattt caatatcgct atgctgcggc agcatttaac cccttgtaat tcatcgccat
    14041 aattgattta attcacaaat aaaactataa catggtgaaa tcaatgaaaa aaaacacaga
    14101 tgatggggct aaaatttaca caccacttac cctaaagctt tatgactggt gggttttggg
    14161 agtatcaaat cggcttgcat ggggatgtcc tacaaaggaa caccttcttc cacactttct
    14221 ggaacatgta ggtaacaacc atctggatat tggtgttgga actgggtttt accttactca
    14281 cgtacctgag agtagtctga tatctttaat ggatttgaac gaagctagcc tgaacgcggc
    14341 atctacaagg gctggggaat caaaaattaa acataaaatt agccatgatg tttttgaacc
    14401 ttatcccgcg gcgttacatg gtcaatttga ttccatttcc atgttttacc ttcttcactg
    14461 cctgcctgga aatatatcta caaaaagctg tgtaatacgc aatgcggcgc aggccttaac
    14521 tgacgatgga actctatacg gagccacaat tcttggcgat ggagttgtgc acaatagctt
    14581 cggtcaaaaa ctgatgcgca tttacaatca gaaaggcatc ttttcaaaca caaaagattc
    14641 cgaagaaggc ttaacacaca tactctcaga gcatttcgag aatgttaaaa ccaaggttca
    14701 aggtactgta gtaatgtttt ccgcttcagg gaaaaaatag catccaaccg cagcacgttc
    14761 ttgcttaaga cgtgctgcgg cataatccca atgattactc cctgacagga tttacaggcc
    14821 actcaatatc aggtgcagtt gatgtatcaa cacggttcag caatacccga tactttttcc
    14881 aggcttccag caatgaggtt tcttcctccg ttgcaatttc cagatctgca gcatcctgaa
    14941 gcggcgcaat atgctcactg gctacctgca tcaggttgtt ttttgtttct tccgcctccc
    15001 ggatccggaa cagtttttct gcttccgtat ccttcaccca ggctgtgccg ttccacttct
    15061 gaaactcccc ttccggcgat aaccaggtaa cattttccgg taacggaccg agttcagaaa
    15121 taaataactc gtcccctgac gctacgtcat aaaccgtttt accccgatgg tcttcaacga
    15181 gatgccacga tgcctcatca ctgttgaaaa cagccacaaa gccagcagga atatctggtg
    15241 gtgcaatatc ggtactgttt gctggcagac ctgtatgagg cggaatatat gcgtcacctt
    15301 caccaataaa ttcattagtt ccggccagca gattataaat ttttatggtc cgtgcttgtt
    15361 cactcattct gaatgccatt atgcaagcct cacaatatag ttaaatgcga tgtttttgac
    15421 ggtgttttcc gcgttacccg cagcgttaac ggtgatggtg tgtccatgtg aaccaatcgc
    15481 aacggagtgc gtatgcgcac caatacctac agtatgtgca tgtgcgccag aacttgctgc
    15541 agtaccagac agcgagtggg tatgagcacc tgctgactgt gtctgaatac gttgataata
    15601 cgatctatag gaagaagtct ccgggcttac ttgatactgt gaattctgga cataagtgaa
    15661 cccaccgcca tcataaaatg ctaacgcaga accgccgcct cctggccaac gaataccatt
    15721 accatgagta tgaacaccgg cagaccccgt agagccactc agactgtgcg tatgcgcccc
    15781 ggtgttattc gtggatttag tgccgtaatc aaacgacgat gtggttttcg tccccaaatc
    15841 cgtactggat gcgctggcgc tgtgggtgtg cgatttaatg ccgtcctgtt cctgagacaa
    15901 tacggcccgg ccactggcgg gtttgccctt gattgtccag ccgcgcatat ctggaataac
    15961 acctgaagga taggcaatag ccagtttcgg atatgctgcc ttatcaaacg tctgcccctg
    16021 catgattgca taacctgcag gtggtgtatc tgatggccac ggcagcggaa cacctggcgg
    16081 aaacgcttca atatttgccg agccgtcaaa ttttacgccg ttaattgtcc ttgcagtttg
    16141 caatttggtt gctgtgcttg cattacccga taaagatcca gtgataccac cactcgcgtt
    16201 taatttagtt gcaattgtaa cattgccagt atggttacta attataaacg gccttaagct
    16261 attgtgcgta ccaagactgt tacccgaatc tgtcaacata aaatatgtgt ttgatccatc
    16321 atttcggata aagaatccat agttgccata ggcaatacgc agaccatttg ctgaccttga
    16381 aataacctca ccagcagcag ttaaaccacc tgaaagagtc cctccagtta atgccaatgc
    16441 cccaatattt gaaggggtca atgtgatatt tgcactacca tcaaatgaca caccgttaat
    16501 cgttctggct gcctgaagtt tcgtggcggt cgcagcatta cctgtagtgt tttgattacc
    16561 ggtagcgttg actccaggca agttgatatc tgccgatcca tcaaatgcca cgcccccaat
    16621 cttacgtgct gtcttgatct tggtcgcagt atctgcgttt ccggtcaaat taccagtaac
    16681 actaccacca acttttagtc cattaccgat ggacaccaac cctgatctta agtttataga
    16741 gaatggtctt aatgaaccga tgtctccatt ttccccctcc ccttcattag tcggaataag
    16801 atgaagatga tcttcggaac gcctaaaaat aaggccaaag gcttggttga atattcgaag
    16861 agcatttatc gtgctgattt ttaactgccc tcccattgtg tcgccagttt tttgaactga
    16921 actatcttta acagttttaa ctgcctttgg cgttgccgcc agcttttcac tggtgctgtt
    16981 tgttgcactg ctgagctgta ctatcccctt tttcgtcgtg ctcgcatcct ccagcgccac
    17041 ggcggatgca atatcctctg cccgttttgc tgctgtctcg gcgcgcgttg ccgcggattc
    17101 agcagcaact ttgctctgag atgcagccgt cgcactgcct gccgcctctg atgctttcgt
    17161 tgttgctgtc gtggcactac ctttcgctgc tgacgcttgt ctggtcgcct catcttttga
    17221 agcagacgca gatgatgccg atgacgccgc tgaactggct gacgatgcgg ctgccgcctt
    17281 agaggaagca gcattgtctg ctgaagtctt tgcatttgtt tcagaggttt ttgctgcaga
    17341 agcagacctc gctgctgcag tggcttgctc agtggctttg ccagccttcg ttgtggctgt
    17401 tgaagcggat gatgcggcgc tttctgccga ttttccggcg gcggtggcac tggctgaggc
    17461 ctgcccggca cttgttgacg cggcactggc agataatgca gccgctgttt ttgaacctgc
    17521 cgcagctgag gcgctctgtc ccgctgctgt ttcagaagac ttagcgttcg tctcggacgt
    17581 ttttgccgcc ttcgcggaat ttcctgccgc cgttgccgag gaagctgcac tactggcact
    17641 tgatgatgca ttcgtttctg aagatttcgc tgcctctttt gaggccgccg caccccgtgc
    17701 cgaggtggca gcttctgacg ccttcgtggt cgctgtggat gcagaagtgg ctgccgattt
    17761 ttgtgatgct gcggcattcg tttctgacgt tttcgcggca ctggcgctgg tagctgccgc
    17821 gctttttgat gactctgcag cagcagcact ttttgctgct tcacgggcct ttgtcgatgc
    17881 cgttcctgcg ctggaagacg ctgactgagc cgacgacgcg gcctgtccgg ctgacgtgct
    17941 ggcggcacgt gctgaggctg cagcatcggt tgctgatgca ctggcatcgc tggctgattt
    18001 tttcgcggct gccgtattct gtgcaaccgc tgaggcgtta cgtgacacct cttccaccat
    18061 ctgctcaaag cggcgcagtg cctccggtcg gacatcatcc tccgtcatgg caccgagaaa
    18121 atcattcagc gtacctggtc tggaaccttc atagacggta atggtcccgg catgtgaagg
    18181 cggaaaacct tcaaccagca gggtgacgct gtactgacca tgctcaacat ccatgctgta
    18241 acgtccggct tcatccggat tttcagaggc caccgtgttc accaccaccg tgctgctggt
    18301 tcgtctggcc ttcagcacaa tggtgcagtt ctgtactggt tttcctgtgc catctttaag
    18361 cacgccagaa atttttactg tcatactttt ccaccaataa aaaaagcccg cagcagtgac
    18421 gccacgggct tcaggacagt gtaactttac gtttcctcaa acgcagttca ccccataagg
    18481 tggatgaacc tgcgtatcat aacaatattt acagaagata aatcggcgtc tgttgtcaga
    18541 aacggtatcc gataccaaca ataaatgcat ccgttcgcca gtcgccacta ccggaacctt
    18601 cataagcaag gtcaatggtc acggattcgg tcgggttaaa ctgcacgcca gccccccacg
    18661 ccagagacgt gttgctgtgg cgaccgtcat cacttccggt cagcacatcg tgcgttttcc
    18721 ccttgttgtc agttacgcgg agataatccc cggagaaagt cgatacacgg ctgtaagcca
    18781 cacccgccat cgcatacgcg ctgaaccatt cattcacgcg tacagacggc cccgccatca
    18841 cgctgaacca gcggttacgc acggaatctt catgccagcg ggtatcgctg tagcgcgttt
    18901 tttgctcatc ctcagcattg gcataactga aggacgtaat cagccccagc gcgtccgtaa
    18961 actcataacg gtatttcacg ttaatcccgt tcagatcatc actaccggga acgttcgtcg
    19021 aggcatggag ataccccgcg ctcagcgtgg actgatgttc tgctgcactc gctggcgtag
    19081 cagcggcgac ctgccagact actgcggaca aaataacagc acataattta cgcataatta
    19141 cctctagctt ttctgcaata aaaaaggcgc catttctggc gcccgtatct gggttataaa
    19201 attcagctaa tcgtgatgcc tgcagtggct ttcttcatca ccacaaccag caaatcgctg
    19261 atacttgctg tgggatacca gttatttacc agccatgctg acaccgaaaa ctccagtgtc
    19321 atgtgaccgt gaccggcagg catatcaata acaccactgt aaatcagcgt attatccagc
    19381 gcggtacggt tataaatttc agcaccgttt ttccgcacta tcagacggca tgaggagtaa
    19441 atatcagtat gctctttctc atgtttagcg ccgctgaatg ccaccgccgg aataacaatc
    19501 tgccggtcaa acggctgatc gtcataaacc ctgacggtaa tggttcctga tggccaccgc
    19561 tccggtgcac gggagtcccg ggggaaagct ttgcccactg ttttaacgag atcgccttca
    19621 atctggttcg cggacaattt tcccagaacc cg
//
LOCUS       DADXDL010000097        19378 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.097, whole genome shotgun sequence.
ACCESSION   DADXDL010000097 DADXDL010000000
VERSION     DADXDL010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 19378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 19378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..19378
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.097"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..73)
                     /locus_tag="IRB70_003895"
     CDS             complement(<1..73)
                     /locus_tag="IRB70_003895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HBC0633751.1"
                     /translation="MASISIRCPSCSATEGVVRNGKST"
     gene            388..1620
                     /gene="mdtM"
                     /locus_tag="IRB70_003896"
     CDS             388..1620
                     /gene="mdtM"
                     /locus_tag="IRB70_003896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter MdtM"
                     /protein_id="HBC0633752.1"
                     /translation="MPRFFARHAATLFFPMALILYDFAAYLSTDLIQPGIINVVRDFN
                     ADVSLAPAAVSLYLAGGMALQWLLGPLSDRVGRRPVLITGALIFTLACAATMFTTSMT
                     QFLIARAIQGTSICFIATVGYVTVQEAFGQTKGIKLMAIITSIVLIAPIIGPLSGAAL
                     MHFVHWKVLFAIIAVMGFISFVGLLLAMPETVKRGAVPFSAKSVLRDFRNVFCNRLFL
                     FGAATISLSYIPMMSWVAVSPVILIDAGGLTTSQFAWTQVPVFGAVIVANAIVARFVK
                     DPTEPRFIWRAVPLQLVGLALLIIGNLLSPHVWLWSVLGTSLYAFGIGLIFPTLFRFT
                     LFSNNLPKGTVSASLNMVILMVMSVSVEIGRWLWFNSGRLPFHLLAVVAGVIVVFTLA
                     GLLNRVRQHQAAELAEER"
     gene            1661..2941
                     /locus_tag="IRB70_003897"
     CDS             1661..2941
                     /locus_tag="IRB70_003897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001741264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF445 domain-containing protein"
                     /protein_id="HBC0633753.1"
                     /translation="MNKLIELRRAKMLALSLLLIAAATFVVTLFLPPNFWVSGVKAIA
                     EAAMVGALADWFAVVALFRRVPIPIISRHTAIIPRNKDRIGENLGQFVQEKFLDTQSL
                     VALIRRHEPALLIGNWFSQPENARRVGQHLLQIMSGFLELTDDARIQRLLKRAVHRAI
                     DKVDLSGTSALMLESMTKNDRHQVLLDTLIAQLIALLQRDKSRKFIAQQIVRWLESEH
                     PLKAKILPTEWLGEHSAELVSDAVNSLLDDISRDRAHQIRHAFDRATFALIEKLKNDP
                     EMAARADAVKSYLKEDEAFNRYLSELWGDLREWLKADINSEDSRVKERIARAGQWFGE
                     TLIADDALRASLNGHLEQAAHRIAPEFSAFLTRHISDTVKSWDARDMSRQIELNIGKD
                     LQFIRVNGTLVGGCIGLILYLLSQLPALFPLGNL"
     gene            3057..4208
                     /locus_tag="IRB70_003898"
     CDS             3057..4208
                     /locus_tag="IRB70_003898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418755.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxyacyl-CoA dehydratase subunit D"
                     /protein_id="HBC0633754.1"
                     /translation="MSLVTDLPAIFDQFSEARQKGFLTVMDLKERGIPLVGTYCTFMP
                     QELPMAAGAVVVSLCSTSDETIEEAEKDLPRNLCPLIKSSYGFGKTDKCPYFYFSDLV
                     VGETTCDGKKKMYEYMAEFKPVHVMQLPNSVKDDASRALWKAEILRLQKTVEERFGHE
                     ISEDALRDAIALKNRERRALANFYHLGQLNPPALSGSDILKVVYGATFRFDKEALINE
                     LDAMTARVRQQWEEGQRLDPHPRILITGCPIGSAAEKVVRAIEENGGWVVGYENCTGA
                     KATEQCVAETGDVYDALADKYLAIGCSCVSPNDQRLQMLSQMVEEYQVDGVVDVILQA
                     CHTYAVESLAIKRHVRQQHNIPYIAIETDYSTSDVGQLSTRVAAFIEML"
     gene            4218..4985
                     /locus_tag="IRB70_003899"
     CDS             4218..4985
                     /locus_tag="IRB70_003899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001298028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633755.1"
                     /translation="MTYSIGIDSGSTATKGILLADGVITRRFLVPTPFRPATAITEAW
                     ETLREGLETTPFLTLTGYGRQLVDFADKQVTEISCHGLGARFLEPATRAVIDIGGQDS
                     KVIQLDDDGNLCDFLMNDKCAAGTGRFLEVISRTLGTSVEQLDSITENVIPHAITSMC
                     TVFAESEVISLRSAGVAPEAILAGVINAMARRSANFIARLSCEAPILFTGGVSHCQRF
                     THMLESHLGMPVQTHPDAQFAGAIGAAVIGQRQRKRA"
     gene            4982..5239
                     /locus_tag="IRB70_003900"
     CDS             4982..5239
                     /locus_tag="IRB70_003900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3343 domain-containing protein"
                     /protein_id="HBC0633756.1"
                     /translation="MKEYLFLFHSTVGVIQTRKALQAAGMTFRVSDIPRELRGGCGLC
                     IWLTCPPGEEIQWVIPGLTESIYCQQDGVWRCIAHYGVSPR"
     gene            5304..6164
                     /locus_tag="IRB70_003901"
     CDS             5304..6164
                     /locus_tag="IRB70_003901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418753.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiK family protein"
                     /protein_id="HBC0633757.1"
                     /translation="MTKSISLSKRISVIVILFAIVAVCTFFVQSCARKSNHAASFQNY
                     HATIDGKEIAGITNNISSLTWSAQSNTLFSTINKPAAIVEMTTNGDFIRTIPLDFVKD
                     LETIEYIGDNQFVISDERDYAIYVISLTPNSEVKILKKIKIPLQESPTNCGFEGLAYS
                     RQDHTFWFFKEKNPIEVYKVNGLLSSNELHISKDKALQRQFTLDDVSGAEFNQQKNTL
                     LVLSHESRALQEVTLAGEVIGEMSLTKGSRGLSHNIKQAEGVAMDASGNIYIVSEPNR
                     FYRFTPQSSH"
     gene            6232..7410
                     /locus_tag="IRB70_003902"
     CDS             6232..7410
                     /locus_tag="IRB70_003902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633758.1"
                     /translation="MPSPSHPVERFSFSTALFGMLVLTLGMGLGRFLYTPMLPVMMAE
                     GSFSFSQLSWIASGNYAGYLAGSLLFSFGAFHQPSRLRPFLLASALASGLLILAMAWL
                     LPFILVLLIRVLAGVASAGMLIFGSTLIMQHTRHPFVLAALFSGVGIGIALGNEYVLA
                     GLHFDLSSQTLWQGAGALSGMMLIALTLLMPSKKHAITPMPLAKTEQQIMSWWLLAIL
                     YGLAGFGYIIVATYLPLMAKDAGSPLLTAHLWTLVGLSIVPGCFGWLWAAKRWWALPC
                     LTANLLVQAICVLLTLASDSPLLLIISSLGFGGTFMGTTSLVMTIARQLSVPGNLNLL
                     GFVTLIYGIGQILGPALTSMLGNGTSALAGATLCGAAALFIAALISTVQLFKLQVVTS
                     "
     gene            complement(7423..7977)
                     /gene="kptA"
                     /locus_tag="IRB70_003903"
     CDS             complement(7423..7977)
                     /gene="kptA"
                     /locus_tag="IRB70_003903"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001151849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2'-phosphotransferase"
                     /protein_id="HBC0633759.1"
                     /translation="MAKYNEKELADTSKFLSFVLRHKPEAIGIVLDREGWADIDKLIL
                     CAQKAGKRLTRALLDTVVATSDKKRFSYSSDGRCIRAVQGHSTSQVAISFAEKTPPQF
                     LYHGTASRFLDEIKKQGLIAGERHYVHLSADEATARKVGARHGSPVILTVKAQEMAKR
                     GLPFWQAENGVWLTSTVAVEFLEW"
     gene            8227..8910
                     /locus_tag="IRB70_003904"
     CDS             8227..8910
                     /locus_tag="IRB70_003904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418750.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633760.1"
                     /translation="MTQQGDAVAGELATEKVGIKGYLAFFLTIIFFSGVFSGTDSWWR
                     VFDFSVLNGSFGQLPGANGATTSFRGAGGAGAKDGFLFALELAPSVILSLGIISITDG
                     LGGLRAAQQLMTPVLKPLLGIPGICSLALIANLQNTDAAAGMTKELAQEGEITERDKV
                     IFAAYQTSGSAIITNYFSSGVAVFAFLGTSVIVPLAVILVFKFVGANILRVWLNFEER
                     RNPTQGAQA"
     gene            8907..9368
                     /locus_tag="IRB70_003905"
     CDS             8907..9368
                     /locus_tag="IRB70_003905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjiG family protein"
                     /protein_id="HBC0633761.1"
                     /translation="MTTQVRKNIMDMFIDGARRGFTIATTNLLPNVVMAFVIIQALKI
                     TGLLDWVGHICEPVMALWGLPGEAATVLLAALMSMGGAVGVAASLATAGALTGHDVTV
                     LLPAMYLMGNPVQNVGRCLGTAEVNAKYYPHIITVCVINALLSIWVMQLIV"
     gene            9381..10553
                     /gene="iadA"
                     /locus_tag="IRB70_003906"
     CDS             9381..10553
                     /gene="iadA"
                     /locus_tag="IRB70_003906"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBC0633762.1"
                     /translation="MIDYTAAGFTLLQGAHLYAPEDRGICDVLVANGKIIAVASNIPS
                     DIVPDCTVVDLSGQILCPGFIDQHVHLIGGGGEAGPTTRTPEVALSRLTEAGVTSVVG
                     LLGTDSISRHPESLLAKTRALNEEGISAWMLTGAYHVPSRTITGSVEKDVAIIDRVIG
                     VKCAISDHRSAAPDVYHLANMAAESRVGGLLGGKPGVTVFHMGDSKKALQPVYDLLEN
                     CDVPISKLLPTHVNRNVPLFEQALEFARKGGTIDITSSIDEPVAPAEGIARAVQAGIP
                     LARVTLSSDGNGSQPFFDDEGNLTHIGVAGFETLLETVQVLVKDYDFSISDALRPLTS
                     SVAGFLNLSGKGEILPGNDADLLVMTPELRIEQVYARGKLMVKDGKACVKGTFETA"
     gene            10618..11529
                     /gene="hypT"
                     /locus_tag="IRB70_003907"
                     /gene_synonym="qseD"
     CDS             10618..11529
                     /gene="hypT"
                     /locus_tag="IRB70_003907"
                     /gene_synonym="qseD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypochlorite stress DNA-binding transcriptional
                     regulator HypT"
                     /protein_id="HBC0633763.1"
                     /translation="MDDCGAVLHNIETKWLYDFLTLEKCRNFSQAAVSRNVSQPAFSR
                     RIRALEQAIGVELFNRQVTPLQLSEQGKIFHSQIRHLLQQLESNLAELRGGSDYAQRK
                     IKIAAAHSLSLGLLPSIISQMPPLFTWAIEAIDVDEAVDKLREGQSDCIFSFHDEDLL
                     EAPFDHIRLFESQLFPVCASDEHGEALFNLAQPHFPLLNYSRNSYMGRLINRTLTRHS
                     ELSFSTFFVSSMSELLKQVALDGCGIAWLPEYAIQQEIRSGQLVVLNRDELVIPIQAY
                     AYRMNTRMNPVAERFWRELRELEIVLS"
     gene            complement(11522..11914)
                     /gene="iraD"
                     /locus_tag="IRB70_003908"
     CDS             complement(11522..11914)
                     /gene="iraD"
                     /locus_tag="IRB70_003908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418746.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraD"
                     /protein_id="HBC0633764.1"
                     /translation="MMRQSLQAVLPEISGNKTSPLRKSVCSDLLTLFNSPHSALPSLL
                     VSGMPEWQVHNPSDKHLQSWYCRQLRSALLFHEPRIAALQVNLKEAYCHTLAISLEIM
                     LYHDDESLTFDLVWDNGGWRSATLENVS"
     gene            complement(11911..11994)
                     /gene="idlP"
                     /locus_tag="IRB70_003909"
     CDS             complement(11911..11994)
                     /gene="idlP"
                     /locus_tag="IRB70_003909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iraD leader peptide IdlP"
                     /protein_id="HBC0633765.1"
                     /translation="MENEHQYSGARCSGQAAYVAKRQECAK"
     gene            12586..13372
                     /locus_tag="IRB70_003910"
                     /pseudo
     CDS             12586..13372
                     /locus_tag="IRB70_003910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313311.3"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2686 family protein"
     gene            complement(13513..14286)
                     /gene="uxuR"
                     /locus_tag="IRB70_003911"
     CDS             complement(13513..14286)
                     /gene="uxuR"
                     /locus_tag="IRB70_003911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Uxu operon transcriptional regulator"
                     /protein_id="HBC0633766.1"
                     /translation="MKSATSAQRPYQEVGAMIRDLIIKTPYNPGERLPPEREIAEMLD
                     VTRTVVREALIMLEIKGLVEVRRGAGIYVLDSSGSHNTDSPDANVCNDAGPFELLQAR
                     QLLESNIAEFAALQATREDIVKMRQALQLEERELASSAPGSSESGDMQFHLAIAEATH
                     NSMLVELFRQSWQWRENNPMWIQLHSHLDDSLYRKEWLGDHKQILAALIKKDARAAKL
                     AMWQHLENVKQRLLEFSNVDDIYFDGYLFDSWPLDKVDA"
     gene            complement(14501..15961)
                     /locus_tag="IRB70_003912"
     CDS             complement(14501..15961)
                     /locus_tag="IRB70_003912"
                     /EC_number="1.1.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructuronate reductase"
                     /protein_id="HBC0633767.1"
                     /translation="MTTIVDSNLPVARPSWVHSRLESRIVHLGCGAFHRAHQALYTHH
                     LLESTDSDWGICEVNLMPGNDRVLIENLKKQQLLYTVAEKGAESTELKIIGSMKEALH
                     PEIDGCEGILNAMARPQTAIVSLTVTEKGYCADAASGQLDLNNPLIKHDLENPTAPKS
                     AIGYIVEALRLRREKGLKAFTVMSCDNVRENGHVAKVAVLGLAQARDPQLAAWIEENV
                     TFPCTMVDRIVPAATPETLQEIADQLGVYDPCAIACEPFRQWVIEDNFVNGRPDWDKV
                     GAQFVADVVPFEMMKLRMLNGSHSFLAYLGYLGGYETIADTMTNPDYRKAAFALMMQE
                     QAPTLSMPEGTDLNAYATLLIERFSNPSLRHRTWQIAMDGSQKLPQRLLDPVRLHLQN
                     GGSWRHLALGVAGWMRYTQGVDEQGNAIDVVDPMLAEFQKINAQYQGADRVKALLGLS
                     GIFADDLPQNADFVGAVTAAYQQLCERGARECVAAL"
     gene            complement(16042..17226)
                     /gene="uxuA"
                     /locus_tag="IRB70_003913"
     CDS             complement(16042..17226)
                     /gene="uxuA"
                     /locus_tag="IRB70_003913"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709912.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBC0633768.1"
                     /translation="MEQTWRWYGPNDPVSLADVRQAGATGVVTALHHIPNGEVWSVEE
                     ILKRKAIVEDAGLVWSVVESVPIHEDIKTHTGNYEQWIANYQQTLRNLAQCGIRTVCY
                     NFMPVLDWTRTDLEYVLPDGSKALRFDQIEFAAFEMHILKRPGAEADYTEEEIAQAAV
                     RFATMSDEDKARLTRNIIAGLPGAEEGYTLDQFRKHLELYKDIDKAKLRENFAVFLKA
                     IIPVAEEVGVRMAVHPDDPPRPILGLPRIVSTIEDMQWMVDTVNSMANGFTMCTGSYG
                     VRADNDLVDMIKQFGPRIYFTHLRSTMREDNPKTFHEAAHLNGDVDMYEVVKAIVEEE
                     HRRKAEGKEDLIPMRPDHGHQMLDDLKKKTNPGYSAIGRLKGLAEVRGVELAIQRAFF
                     SR"
     gene            17566..18909
                     /gene="gntP"
                     /locus_tag="IRB70_003914"
     CDS             17566..18909
                     /gene="gntP"
                     /locus_tag="IRB70_003914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate permease GntP"
                     /protein_id="HBC0633769.1"
                     /translation="MHVLNILWVVFGIGLMLVLNLKFKINSMVALLVAALSVGMLAGM
                     DLMSLLHTMKAGFGNTLGELAIIVVFGAVIGKLMVDSGAAHQIAHTLLARLGLRYVQL
                     SVIIIGLIFGLAMFYEVAFIMLAPLVIVIAAEAKIPFLKLAIPAVAAATTAHSLFPPQ
                     PGPVALVNAYGADMGMVYIYGVLVTIPSVICAGLILPKFLGNLERPTPSFLKADQPVD
                     MNNLPSFGVSILVPLIPAIIMISTTIANIWLVKDTPAWEVVNFIGSSPIAMFIAMVVA
                     FVLFGTARGHDMQWVMNAFESAVKSIAMVILIIGAGGVLKQTIIDTGIGDTIGMLMSH
                     GNISPYIMAWLITVLIRLATGQGVVSAMTAAGIISAAILDPATGQLVGVNPALLVLAT
                     AAGSNTLTHINDASFWLFKGYFDLSVKDTLKTWGLLELVNSVVGLIIVLIISMVA"
     gene            complement(19083..19253)
                     /locus_tag="IRB70_003915"
                     /pseudo
     CDS             complement(19083..19253)
                     /locus_tag="IRB70_003915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313306.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
     gene            19308..>19378
                     /locus_tag="IRB70_003916"
     CDS             19308..>19378
                     /locus_tag="IRB70_003916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1 family transposase"
                     /protein_id="HBC0633770.1"
                     /translation="MASVSISCPSCSATDGGVRNGKST"
BASE COUNT         4483 a         4919 c         4936 g         5040 t
ORIGIN      
        1 cagtgctttt gccgttacgc accacgcctt cagtagcgga gcaggaagga catctgatgg
       61 aaatggaagc cacgcaagca ccttaaaatc accatcatac actaaatcag taagttggca
      121 gcattaccaa attttaatta cacttaaggt gtatattttc tatgcaagcc atcaattaaa
      181 gaggtgtaat gtgctgatga ctatttgtaa tcgttataca ttctgacctg gagtcagaag
      241 gtatttctct gtctgtgtat tcgcaggcag tgtggttgat tacatgaaat tcagtacatt
      301 tgtccttctc gcctgccttt cgtcattacc gacggtattg aatttcgttt tccccattgg
      361 ggttctccgg acaaggagtt gtttgttatg ccacgttttt ttgcccgcca tgccgccacg
      421 ctgtttttcc cgatggcgtt gattttgtat gactttgctg cgtatctgtc gacggacctg
      481 atccagccag ggatcattaa tgtggtccgt gattttaatg ccgatgtcag tctggccccg
      541 gctgccgtca gtctctatct cgctggaggc atggcattgc agtggctgct ggggccgctt
      601 tccgacaggg ttggccgcag gccggtgctg attaccgggg cgctaatatt tacccttgcc
      661 tgcgctgcga caatgttcac aacgtctatg acacagtttc ttatcgcgcg tgcaattcag
      721 ggcaccagta tctgttttat tgccaccgtt ggttatgtca cggtgcagga ggcgttcgga
      781 cagacaaaag ggatcaagtt gatggcgatt atcacctcca tcgtactgat tgcgccgatt
      841 attggcccgc tttccggcgc agctctgatg cactttgtgc actggaaagt cctttttgcc
      901 atcattgcgg ttatgggttt tatctcattt gttggcttac tgctggcgat gccagagacg
      961 gtgaagcgcg gcgcggttcc atttagcgcc aaaagcgtct tgcgcgattt tcgtaatgtc
     1021 ttttgcaatc ggctgttcct ctttggcgca gcaaccatct ctttaagcta tatccccatg
     1081 atgagttggg tggctgtctc gccggtgatc ctgattgacg caggcggctt aacaacttcg
     1141 cagttcgcct ggacacaggt tccggtgttc ggcgcggtga ttgtcgcgaa tgccatcgtg
     1201 gcgcgtttcg ttaaagatcc gaccgaaccg cgctttatct ggcgtgccgt accccttcaa
     1261 ctggttggcc tcgcgctgtt gattatcggc aatctgctgt caccgcacgt ctggctgtgg
     1321 tcggtgctgg gcaccagtct gtatgctttc gggattggtt tgattttccc gaccttattc
     1381 cgctttacgc tgttttccaa taacttaccg aaagggaccg tctccgcatc gctgaatatg
     1441 gtgatcctga tggtgatgtc tgtctcggtc gaaatcggcc gctggctgtg gtttaacagc
     1501 ggtcgcttgc cgtttcatct gttagccgtt gtggcaggcg ttatcgtcgt tttcaccctg
     1561 gccggattgc ttaatcgcgt gcgccaacat caggctgccg agctggcgga ggagcggtga
     1621 tttttgcgcg atcctgccgt caggctctat tcttaacatt atgaataaac tcattgaact
     1681 cagacgcgcc aaaatgttgg cgctctcttt actgcttatc gccgctgcta cctttgtcgt
     1741 tacgctgttt ttgccgccca atttttgggt gagcggcgtg aaggcgattg ctgaagcggc
     1801 gatggtcggc gcgctggcgg actggtttgc ggtggtggcg ctgtttcgcc gcgtgccgat
     1861 tccgatcatt tctcgtcata cggcgattat tccgcgtaat aaagaccgga ttggcgaaaa
     1921 tctcggccag ttcgtgcagg aaaaatttct cgatacccaa tcgctggtgg cattgattcg
     1981 acgtcacgaa ccggcgttgt tgattggcaa ctggtttagt cagccagaaa acgcccgccg
     2041 cgttggtcag catctgttgc agatcatgag cggttttctt gaactaaccg atgatgcgcg
     2101 tattcagcgc ctgcttaagc gcgcggtcca ccgggcgatt gataaagtcg atctttctgg
     2161 caccagtgcg ttgatgctgg agagtatgac taaaaacgat cgtcatcagg tgctgctgga
     2221 tacgctgatc gcacagttga tcgcccttct ccagcgcgat aaatcgcgca agtttattgc
     2281 ccagcaaatt gttcgctggc tggagagcga gcatccactg aaagccaaaa ttttgcccac
     2341 tgaatggctg ggcgaacata gcgcggagtt ggtttctgac gcggtgaatt ctttgcttga
     2401 tgatatcagc cgcgatcgtg cgcatcagat ccgccatgcg tttgatcgcg ctaccttcgc
     2461 cctgatcgag aaactgaaaa acgatccgga aatggcggcg cgagccgatg ccgtaaaaag
     2521 ctatctgaaa gaagatgaag cttttaaccg ctatctcagt gaattgtggg gggatttacg
     2581 ggaatggctg aaagcggata tcaacagtga agattctcgt gtgaaagaac gtatcgcgcg
     2641 ggctggtcaa tggtttggcg aaacgttaat tgccgatgat gccttgcggg cgtcgttaaa
     2701 tggtcatctg gaacaagccg cacaccgcat tgcgcctgag ttttccgcat tcctgactcg
     2761 ccatatcagc gacacggtaa aaagctggga cgcacgggac atgtcgcggc aaatcgagtt
     2821 aaatatcggc aaagatctcc agtttatccg tgtcaacggt acgctggttg gcggttgtat
     2881 tggacttatt ttgtatttgc tgtcgcagct cccggccttg ttccccctcg gcaatttata
     2941 gaaatccatg aaaaactaag tggctaaccg cgagagagat caaataaacc acactaaaag
     3001 aatggtaata atgtggcctc ttttcattat ctcccgtggt acggggaagg aaaatcatgt
     3061 cacttgtcac cgatctaccc gccattttcg atcagttctc tgaagctcgc cagaaaggct
     3121 ttctcaccgt catggatctc aaggagcgcg gcattccgct ggttggcacc tactgcacct
     3181 ttatgccgca agagctcccg atggcagccg gtgcggttgt ggtttcgcta tgttccacct
     3241 ctgatgaaac cattgaagaa gccgagaaag atctgccgcg caacctctgc ccgctgatta
     3301 aaagcagcta cggcttcggc aaaaccgata aatgccccta cttctacttt tctgatctgg
     3361 tggtcggtga aaccacctgc gacggcaaaa agaaaatgta tgaatacatg gcggagttta
     3421 agcccgttca tgtgatgcaa ctgccaaaca gcgttaagga cgatgcctcg cgtgcattat
     3481 ggaaagccga gatactgcgc ttgcaaaaaa cggtagaaga acgttttggg cacgagatta
     3541 gcgaagatgc tctgcgcgat gccattgcgc tgaaaaaccg cgaacgtcgc gcactggcaa
     3601 acttttatca tttggggcag ttaaatcctc cagcgcttag cggcagcgac attctgaaag
     3661 tagtctacgg cgcaaccttc cggttcgata aagaggcgtt gatcaatgaa ctggatgcaa
     3721 tgaccgcccg cgttcgtcag cagtgggaag aaggccagcg actggacccg cacccacgta
     3781 ttttaatcac cggctgccca attggcagcg cagcagagaa agtggtgcgc gcgattgaag
     3841 agaatggcgg ctgggttgtc ggttatgaaa actgcaccgg ggcgaaagcc accgagcaat
     3901 gcgtggcgga aacgggtgat gtgtacgacg cgctggcgga taaatatctg gcgattggct
     3961 gctcctgtgt ttcgccgaac gatcagcgcc tgcaaatgct cagccagatg gttgaagaat
     4021 atcaggtcga tggcgtagtt gatgtgattt tgcaggcgtg ccatacctac gcggtggaat
     4081 cgctggcgat taaacgtcat gtgcgccagc agcacaacat tccttatatc gctattgaaa
     4141 cagactactc cacctcggat gtcgggcagc tcagcacccg tgtcgcggcc tttattgaga
     4201 tgctgtaagg agtggcagtg acatattcga ttggcattga ttccggctca accgccacca
     4261 aagggatctt actggctgac ggcgtgatta cgcgccgttt cctcgttcca acaccctttc
     4321 gcccggcaac agcaattact gaagcctggg aaactctgcg cgaagggtta gagacaacgc
     4381 cgtttctgac gctcaccggc tacggacggc aactggtgga ttttgccgat aaacaagtga
     4441 cggaaatctc ctgtcacggg ctgggcgcac ggtttcttga gccagcaacg cgcgcggtaa
     4501 tcgacatcgg tggtcaggac agcaaagtga ttcagcttga tgatgacggt aacctgtgcg
     4561 atttcctgat gaatgacaaa tgcgcggcgg gcaccgggcg tttcctggag gtgatctcgc
     4621 gcacgcttgg caccagcgtc gagcaactcg acagcattac cgaaaatgtc ataccgcacg
     4681 ccatcacgag tatgtgcaca gtgtttgctg aatcagaagt gatcagcctg cgctctgcgg
     4741 gcgtagcgcc agaagcgatt ctcgccggag tgattaacgc gatggcgcgg cggagcgcca
     4801 atttcattgc tcgtctctcc tgtgaagcgc cgattctgtt tactggtggc gttagccact
     4861 gtcaaaggtt tacccacatg ctggaaagcc atctgggaat gccggtacaa actcaccctg
     4921 atgcgcaatt cgctggtgca attggcgcgg cggtgatcgg tcagcggcag agaaaacgcg
     4981 catgaaagag tatctgtttt tatttcactc cacggtcggc gtcatacaaa cccgcaaggc
     5041 gttgcaggca gcgggcatga cttttcgcgt cagcgatatt ccccgtgagt tacgcggcgg
     5101 ctgcgggtta tgcatttggc tgacctgtcc ccccggcgag gaaatacaat gggtgatccc
     5161 tgggctgact gagtcaattt attgccagca ggatggtgtc tggcgctgca ttgcacatta
     5221 cggggtttct ccgcgttaag gattcattaa ggtcgctacg tatacttctc gatatcttat
     5281 tgatttgcct taaagggatt accgtgacaa aaagtatttc gttaagtaaa cgcatctccg
     5341 ttattgtgat tctttttgcc attgtggcag tgtgtacttt cttcgtgcaa tcttgcgccc
     5401 gtaaaagcaa tcatgcagca tcatttcaga attaccacgc caccattgac ggcaaagaaa
     5461 ttgcaggcat aacgaataat atctcttcgc tgacctggtc ggcacaaagc aatactcttt
     5521 ttagcactat caacaaacct gccgccattg ttgaaatgac caccaatggt gattttatcc
     5581 gcacaattcc tctggatttt gttaaggatc tcgagacgat cgaatacatt ggcgataatc
     5641 agtttgtcat tagcgatgag cgcgattatg ccatttatgt gatttcactg accccaaact
     5701 cggaagtaaa aatcctcaaa aaaataaaaa tcccgctgca ggaatcccca accaattgcg
     5761 gttttgaagg attggcctat tctcgccagg atcacacttt ctggtttttt aaagagaaaa
     5821 acccgattga ggtctacaaa gttaacgggc tgttaagtag caatgaattg cacatcagca
     5881 aagacaaggc actacaacgg caatttactt tagatgatgt gtccggcgca gaatttaacc
     5941 aacaaaaaaa tacgcttctg gtgctgtctc atgaatctcg cgcactccag gaagtaacgc
     6001 tggctggcga ggttataggt gaaatgtcac taaccaaagg cagtcgaggt ttgtcgcata
     6061 acatcaaaca ggccgaaggg gttgcgatgg atgcctcagg taatatttat atcgttagcg
     6121 aaccaaatcg tttttatcgc tttacccctc aatcatcgca ttaacaggct ggcatgtttc
     6181 acctttttgt tattaacttg ttaacaacaa aaatgacaaa caaggttaaa catgccttcg
     6241 ccctcgcatc ccgtagaacg cttttctttc agcaccgcgc ttttcgggat gctggttctg
     6301 accttaggta tgggtttagg ccgcttcctt tatacgccta tgttgcccgt catgatggcg
     6361 gaaggatcgt tttcatttag ccagctctcg tggattgcca gcggcaacta tgcggggtat
     6421 ctggctggca gtctgctatt ttcgtttggc gcatttcacc agccatcgcg cctgcgccca
     6481 tttctgttgg cttctgccct ggcgagcggg ttgttgatcc tcgcaatggc atggttgctg
     6541 ccatttattc tggtgttatt gattcgcgtc ctggcgggtg tcgccagcgc cggtatgctg
     6601 atttttggtt cgacgctgat tatgcagcac acgcgccatc cttttgtgct ggcagctttg
     6661 ttttctggcg ttggcattgg catcgcactg ggcaatgaat atgttctggc aggcctgcat
     6721 tttgacctct cctcgcaaac gttatggcaa ggcgccgggg cgctttctgg catgatgctg
     6781 attgcactta cgcttttaat gccctcgaaa aaacacgcca tcacaccaat gccattggca
     6841 aaaacggagc aacagataat gagctggtgg ttactggcta ttctgtacgg cctggcggga
     6901 tttggttata tcatcgtcgc gacttacctg ccgctcatgg cgaaagatgc aggctcacca
     6961 ttgttaaccg cccatctctg gacgttagtc ggcttatcaa ttgtgcctgg ttgctttggc
     7021 tggctatggg cagcaaaacg ttggtgggct ttgccctgcc tgacggcgaa tttgctggtg
     7081 caggctatct gtgtgctgct tactctcgcc agcgactcgc ctctcttgct tatcatcagc
     7141 agtcttggtt ttggcggtac ctttatgggc acgacatctc tggtgatgac tatcgcccgc
     7201 caactgagcg taccgggaaa tctcaatctt ttaggctttg tgacgctcat ttacggcatt
     7261 ggacaaatcc tcggcccggc gctgaccagt atgctcggca atggaacatc ggcgcttgcc
     7321 ggcgccactc tctgcggcgc ggcggcgttg tttattgctg cgcttatcag cacagtacaa
     7381 ttatttaagc tgcaagtggt cacttcatga ggagtgtttc ccttaccact caagaaattc
     7441 gaccgcaacc gttgatgtca gccagacccc gttttccgct tgccagaaag ggaggcctcg
     7501 tttcgccatt tcctgtgctt tgacggttaa aataaccggc gatccgtgtc ttgctcccac
     7561 tttgcgtgcc gttgcttcat cagcagagag atgtacgtag tgacgctcac ctgcaatcag
     7621 cccctgtttt tttatctcgt caaggaaacg gcttgccgta ccgtggtaga gaaactgtgg
     7681 cggtgttttt tcggcaaagg aaatagcgac ctgcgaagtc gaatgcccct gaaccgcgcg
     7741 gatgcaccta ccatcactgg aataactaaa acgcttttta tcgctggtgg caaccacggt
     7801 atccagcaat gcacgggtta accgcttgcc cgctttttgg gcacaaagta tgagcttatc
     7861 gatatccgcc catccttcac ggtccagtac gataccaatc gcctccggtt tgtgtcggag
     7921 gacaaaactt aaaaacttgc tcgtatccgc cagctctttt tcgttgtact ttgccatcgc
     7981 gttttcgtcc ctggattatc tgttttttat ttactatgtc attgtcactg ggtttatgaa
     8041 ttttctgcaa ctcaatcctg cgtagaacct tttccacaca gcgtaatttt accgctatgc
     8101 aaaaaacgca tagtcagaaa catacttgca ttttccccat acccacatcg ctgataaggt
     8161 ttttcagctc caggaatttt cctggctcaa gcaacacaca aacacaaaaa aacaatgggg
     8221 attgttatga cacaacaagg ggatgctgta gccggggagc tggcgacaga aaaagtgggc
     8281 attaaagggt atctggcttt ttttctcacc ataatctttt tttccggtgt tttttccggg
     8341 acagacagtt ggtggcgcgt ttttgatttt tccgttctga acggatcgtt tgggcaactg
     8401 cctggtgcga acggagccac cacctcgttt cgcggcgcgg gtggcgcggg ggctaaagat
     8461 ggctttctct ttgcgctgga gctggcaccg tcagtcattc tctctctggg gattatttca
     8521 attaccgatg gtcttggcgg attacgcgcc gcgcagcagt taatgacgcc agtgctaaaa
     8581 ccgttgttgg gcattccagg gatctgctcg ctggcgctga tcgctaacct gcaaaacacc
     8641 gatgccgccg caggtatgac caaagagctg gcgcaggaag gtgaaattac cgaacgcgat
     8701 aaagtgattt tcgccgcata tcaaaccagc ggtagcgcca ttatcaccaa ctacttctct
     8761 tccggcgtcg cggtgtttgc ctttctgggc acgtccgtaa tcgtaccttt agcagtcatc
     8821 ctggtgttta aatttgtcgg agccaacatt ttgcgcgtct ggcttaactt cgaagaacgt
     8881 cgcaacccaa cgcaaggagc gcaagcatga caactcaggt ccgcaaaaac atcatggata
     8941 tgtttatcga tggtgcgcgc cgtggcttta ctatcgccac gaccaacctg ctgccaaacg
     9001 tggtgatggc gtttgtcatc attcaggcgc tgaaaattac cggcctgctc gactgggtgg
     9061 ggcatatctg tgaacccgta atggcgctgt ggggattacc cggtgaagcg gcaaccgtcc
     9121 ttttagccgc attaatgagt atgggtggcg cagtcggtgt tgccgccagt ctggcaaccg
     9181 ctggcgcatt aaccggtcac gatgtcaccg ttttactgcc cgcgatgtat ttaatgggca
     9241 acccggtgca aaatgtcggt cgctgcctgg ggacagccga agtgaatgcc aaatattacc
     9301 cgcatatcat tacggtctgc gtgattaacg cattgctgtc gatctgggtt atgcagctta
     9361 ttgtttaaca aggagttacc atgattgatt ataccgcagc cggttttacc ctgctgcagg
     9421 gagcgcattt gtatgcgccg gaagatcggg gaatttgcga tgtcctcgtc gctaacggca
     9481 aaattatcgc cgttgccagt aatatccctt ctgacattgt accggactgc acggttgtcg
     9541 atctcagcgg gcagatcctc tgcccaggtt ttattgatca acacgtccat ttgattggcg
     9601 gtggcggcga agcaggtccc acgacgcgca cgccggaagt ggcgttaagt cgtctgacgg
     9661 aagcaggcgt cacgtcagtg gttggtctgc tgggcaccga ctctatctct cgccacccgg
     9721 aatccctgct cgccaagacc cgtgcgctca atgaagaagg catcagcgcc tggatgctga
     9781 ccggcgctta tcatgtccct tcccgcacta ttacgggttc cgtggaaaaa gacgtggcga
     9841 ttatcgatcg cgtgattggc gtgaaatgcg ccatctctga tcaccgttct gccgcaccgg
     9901 acgtttatca cctggctaat atggcggcgg aatcccgcgt tggcggtttg ctcggcggta
     9961 aacctggcgt caccgtgttc cacatgggcg acagcaaaaa ggcgttacag cctgtctatg
    10021 acctgctgga aaactgcgat gtgccgatta gcaagttgct gccgacccac gttaaccgca
    10081 acgttccgtt gtttgagcag gcgctggagt tcgcgcgcaa aggcggcacc atcgatatca
    10141 ccagcagcat tgacgaacca gtcgcccctg ccgaaggtat tgcccgcgcc gttcaggcgg
    10201 gtattccgct ggcacgcgtc accctcagct ccgacggcaa cggtagccag ccgttcttcg
    10261 atgacgaagg gaatttaacc catatcggtg ttgccggttt tgaaacgttg ctggaaaccg
    10321 tgcaggtgct ggtcaaagat tatgatttca gtatcagcga tgccctgcgc ccgctcacca
    10381 gtagcgtagc cggtttcctt aacctgagcg ggaaaggcga aattctgcca ggcaatgacg
    10441 cagacttact ggtcatgacg ccagaattac gcattgagca ggtatacgct cgcggcaagc
    10501 tgatggtcaa agacggcaaa gcctgcgtga aaggaacgtt tgaaacggca taaacggttg
    10561 tcagccgccc gaatggacgt agaatgcccg caagggcggc tgacagagta aaacgtaatg
    10621 gatgactgtg gtgcggtttt gcataatatt gaaactaaat ggctttatga ttttctgacc
    10681 ctggaaaaat gccgcaattt ttcccaggca gcagtcagtc gcaacgtctc gcaaccggca
    10741 ttcagccgcc gcatccgtgc gctggaacag gcgattggcg ttgaattgtt taaccgccag
    10801 gtgacgccgc tgcaactctc ggaacaaggt aaaatattcc attcgcagat ccgccatctg
    10861 ttgcaacagt tagagagcaa ccttgcagaa ctccgtggtg gcagcgatta cgcgcaacgc
    10921 aaaattaaaa tagccgctgc acactctctt tccctcgggc tgttaccgtc cattatcagc
    10981 cagatgccgc cgctctttac ctgggcaatt gaagctattg atgtcgatga agcggtcgat
    11041 aaactgcgtg aagggcaaag tgactgtatt ttttcctttc acgacgaaga tttgctggaa
    11101 gcgccgtttg accacattcg cttatttgaa tctcaattgt tccccgtttg cgccagtgac
    11161 gaacacggag aagcactttt taacctcgcg cagccacact ttccgttact gaattacagc
    11221 cgcaactcct acatggggcg attgattaat cgcaccctga cgcgccacag tgagttaagt
    11281 ttcagcacct tttttgtctc ttcgatgagc gagcttttaa agcaggttgc cctcgacggc
    11341 tgtgggattg cctggctacc ggaatacgcc atccaacaag aaattcgcag cgggcagctc
    11401 gttgtactga atcgggacga actggtgatc ccgattcagg cctatgcata ccggatgaat
    11461 acccgcatga atccagttgc cgaacgcttc tggcgtgaac tgcgcgagct ggagattgtg
    11521 cttagctgac attctccagc gtcgcactgc gccaaccgcc attatcccag accagatcaa
    11581 acgttagcga ttcatcgtcg tgatacagca ttatctcaag gctgatcgcc agagtgtggc
    11641 agtacgcttc tttcaaatta acctgcaacg ccgcaatccg tggctcatga aataacagtg
    11701 cagaacgcag ctgacggcaa taccagctct ggagatgttt gtcgctcggg ttatgcactt
    11761 gccactcggg catgcctgaa acaagtaatg acggtaatgc cgaatgagga gaattaaaaa
    11821 gagtgaggag atcgctgcat actgatttac gcagcggtga cgttttattg cctgaaattt
    11881 caggtaaaac agcctgaagt gattggcgca tcattttgcg cactcctgac gtttagcaac
    11941 atatgcggct tgccctgaac accgggcacc actgtattga tgctcatttt ccatagccat
    12001 tcccttttgt tcattacatc catgtcagtc tgagacaggc ctgaatcctg tcagcaaagt
    12061 ataaaacctt acttgcctat gaatatctac tgacttttca ggaaaaaagt catgatttga
    12121 taaaaatcat caaactcaaa aaaaaaccgc tagtatattc tgaatattcc gaatagttac
    12181 gtagatgaaa atacttgtca ccaccgctac ttaattccgg tgggaaatta tttatttccg
    12241 cataatcagc tatgtattat ttaaaacaat tagtttgtaa ataatataaa ttgataacat
    12301 atcaaataca tcaaaaatac cattcacagg cattattaat atagacatca atatagcaac
    12361 atcaaattcc aattagtaat aagatatgct tttaaattgc atgcaaataa ttttaaatga
    12421 gcgttttttg atactttaga gtgtttccca ccatttaata tcactgtgta gagttgatat
    12481 cactacaaca gaaacatgca tgtcatttgt ttacttctct ttttactaca gaaaaattta
    12541 tctatttttc taagcatcag tgaaatactc ataaaggtaa ctattatgtc tatgccatta
    12601 agcaatgccc ttcagagtta aattattaca gataatcact tccttcatca tccaaaagtc
    12661 gacagtgagt taacacgtaa acatgaacgt gcacgcatgg atacggaaaa tatctatctt
    12721 ccgcctcttg ctcgtggcaa taaccataat tacgatggaa aaagcgttgt cgaaattaga
    12781 aaacttgata ttagtaaaga gtcctagcca tttaattatg tgacagaaac atgcagagaa
    12841 ttcaatggta ttacaacaac aggacgtatg ctctatcgaa acttgaaaat cacctcagct
    12901 ttagacgaaa tatatggtgg tatatgtaaa aaggcgcatg ctgccacaga gttagcaaaa
    12961 ggattacggc taaatttatt tatgaaaggc cctttcgatc ctgttgagga ctatacagtt
    13021 catgaaataa cattaggccc tggttgcaat gttcctggtt atgccggaac cacgatagga
    13081 tatatttcaa cccttccagc ttctcaggca aaaagatgga ccaatgagca gccaaggatt
    13141 gatatctata ttgatcagat aataacggta acaggggtag caaattcttc cggattcgcc
    13201 cttgccgcat tacttaatgc taatattgag ttgggtaatg acccaataat tggtatagaa
    13261 gcctatcccg ggtgatgaaa atgcaccact caaacgtatg actctgcaac cgtcatctct
    13321 tccagaactg tttgaattaa aaaatggtga atggaattat attggtaaat aactaccagg
    13381 aagaatgagt actaacattc aggttataca gatagctaaa caatcccctg caatttacaa
    13441 agtaatactc attgcgactt cttaatttaa gaaagcgcaa ggaacgttta cccttgcgct
    13501 tattataata agtcaggcgt cgactttatc cagcggccat gaatcaaaca gatagccatc
    13561 aaaataaata tcgtcaacgt tcgagaattc cagcagacgt tgcttaacgt tttccagatg
    13621 ctgccacatt gccagcttcg ccgctcgggc atcttttttg attaacgcgg cgaggatctg
    13681 tttgtgatcg cccaaccact ctttgcgata caggctgtca tccagatggc tgtgcaactg
    13741 gatccacatt ggattgtttt cccgccactg ccaggactga cggaacagct ccaccagcat
    13801 gctgttatgc gttgcttcgg caatagcgag atggaactgc atgtcaccgc tttcgctgct
    13861 gcccggcgca ctggaagcca gttcacgctc ttccagttgc aatgcctgac gcattttgac
    13921 gatatcttcg cgggtagcct gcagggcggc aaactcggcg atgttgctct caagaagctg
    13981 tcgcgcctgc aacagctcaa aaggacccgc atcattgcaa acgttggcat ccggactgtc
    14041 tgtgttgtgg ctgcctgagc tatcaagaac atagataccg gcaccccggc gcacttccac
    14101 cagccctttg atctccagca tgatcagcgc ttcacgtacc accgtccgcg tgacatcaag
    14161 catttctgca atttcacgct ccggcggcaa ccgttcgcca ggattgtacg gcgtctttat
    14221 gatcagatcg cggatcatcg ccccgacttc ctggtaaggt ctttgcgcag aggtggcaga
    14281 tttcatggtg ttgtgtccgt taggtgcggt taatcaaatt tttgccggat gcggcgtgaa
    14341 cgccttatcc ggcctacaac gggcaatttt acggcacccg ttaatctcaa actataccat
    14401 tagcactgga agttggcacg tacaggtggg caaaaaaacg aaaactggtc aaccaaatat
    14461 cagtttgatt gaccagtaag tctgtagggt aatcagttag ttacagcgca gccacacact
    14521 cgcgcgcacc gcgttcgcac agctgctgat atgccgccgt caccgcgcca acaaagtcgg
    14581 cattctgcgg cagatcatcg gcaaaaatac cgctcaggcc cagcagcgct ttcacgcggt
    14641 ctgcgccctg atactgcgcg ttaatcttct ggaactcggc cagcatcggg tcgaccacgt
    14701 caatggcatt accctgctca tccacgccct gggtgtaacg catccagcca gccacgccca
    14761 gcgccaggtg acgccagctg ccgccgtttt gcaggtgcag acgcaccgga tccagcagac
    14821 gctgcggtaa cttctggctg ccgtccatcg caatctgcca ggtacggtga cgcagagacg
    14881 ggttgctgaa acgctcgatc agcagcgtcg cataggcgtt caggtccgta ccttccggca
    14941 tcgacagcgt tggcgcttgt tcctgcatca tcagggcaaa ggccgctttg cgataatccg
    15001 ggttagtcat ggtgtcggca atagtttcat agccgccgag gtaaccgagg tatgccagga
    15061 aagagtggct gccgttcagc atacgcagct tcatcatttc gaacggcaca acgtctgcaa
    15121 cgaactgtgc gcccacttta tcccagtccg gacgaccatt aacgaagtta tcttcaatca
    15181 cccactgacg gaacggttcg caggcaatgg cgcacgggtc ataaacaccc agctggtcag
    15241 caatttcctg taaggtttct ggcgtcgccg ccggaacgat gcggtcaacc atggtgcacg
    15301 ggaaggtgac gttctcttca atccatgccg ccagctgcgg gtcacgcgcc tgagccagcc
    15361 ccagtaccgc gaccttcgcc acatgaccgt tttcacgcac gttatcgcag gacatcaccg
    15421 taaacgcttt cagccctttt tcacgacgca gacgcagggc ttcgacgatg taaccaatcg
    15481 cagacttcgg cgcagtcggg ttttccagat cgtgcttgat cagcgggtta ttgagatcca
    15541 actgaccgct tgccgcatca gcgcagtagc ctttttccgt gaccgtcaga gagacaatcg
    15601 ccgtctgcgg acgcgccatc gcgttgagaa taccttcgca gccgtcgatt tccggatgca
    15661 gcgcttcttt catcgaaccg ataattttca gttcggtgct ttccgcgcct ttttccgcca
    15721 cggtgtacag cagttgctgt tttttcaggt tttcaatcag cacacggtcg ttacctggca
    15781 tcaggttaac ttcgcagata ccccagtcgc tgtcggtact ttccagcaga tgatgggtat
    15841 acagcgcctg gtgcgcgcgg tgaaacgccc cgcaaccgag atgcacaatg cgtgattcca
    15901 gacgagaatg cacccatgac gggcgggcaa ccggcagatt gctgtcaaca atagtagtca
    15961 tcgtaaactc cagaatccgt cttcagagag tgacggcaag gaagaaggaa ccggcacggc
    16021 gcgcagccat gccggtggat attaacggct aaagaaagcg cgctggatcg ccagttcgac
    16081 accgcgaact tcggccaggc ctttcagacg accaattgcg gagtaacctg ggttagtttt
    16141 cttcttcagg tcgtccagca tctgatgacc gtggtccgga cgcatcggga tcaggtcttc
    16201 tttgccttcc gctttacgac ggtgttcctc ttcaacaatc gctttcacca cttcgtacat
    16261 atcaacgtca ccgttcaggt gcgccgcttc gtggaaggtt ttcgggttat cttcacgcat
    16321 ggtggagcgc agatgggtga agtaaatacg cggaccgaac tgcttgatca tatcaaccag
    16381 atcgttgtca gcacgcacgc cgtaggaacc ggtgcacatg gtgaaaccgt tcgccatgct
    16441 gtttacggta tcaaccatcc actgcatatc ttcaatggtg gaaacaatgc gcggcaggcc
    16501 gaggatcggg cgcggcggat cgtccgggtg aacagccata cggacgccaa cttcttcggc
    16561 aaccggaata atcgctttca ggaagacggc aaagttttcg cgcagtttgg ctttgtcgat
    16621 atctttatat agctccaggt gcttacggaa ctggtcgagg gtgtaccctt cttccgcgcc
    16681 cggaagacca gcaatgatgt tacgggtcag acgcgctttg tcttcgtcgc tcatagtggc
    16741 gaagcgaaca gctgcctgag caatttcttc ttcggtgtaa tccgcttccg cgcctggacg
    16801 tttcaggata tgcatttcga atgcagcgaa ttcgatctgg tcaaagcgca gagctttgga
    16861 gccgtctggc agcacgtatt cgaggtcagt acgggtccag tcgagcaccg gcatgaagtt
    16921 gtagcacacg gtgcgaatgc cgcactgcgc caggttgcgc agagtctgct gatagttagc
    16981 gatccactgc tcatagttgc cagtgtgggt tttgatatct tcgtgaattg gcacgctttc
    17041 tacgacagac cataccaggc ctgcgtcttc aacgatcgcc ttgcgtttga ggatctcttc
    17101 aacggaccat acttcgccgt tcgggatatg gtgcagcgcg gtaaccacgc cagttgcgcc
    17161 cgcctgacgg acatcagcta aagaaaccgg atcgtttggg ccgtaccagc gccaggtctg
    17221 ttccatgatt tttcctcttt cacatagtgg gttccacagc aaagagacgc ggaaccctgg
    17281 agttgtttag gtatccggat gaacaaccag accgcagccg tggcgttgca tcggatgaga
    17341 tggcgtataa gttctacctt ttggtaatac atgtcaaccc gaattctaaa attggttaac
    17401 cacatcacaa gaatttcact ctcctggttg ttgctgcaaa ttgcagcaaa gggtaatcga
    17461 tggttattga tcagaggatg tgacattcat cgcaacaatg gttgaccaat ttacataaca
    17521 tgtcgcccaa aataacaacg gttcaaccag gtaaggtaaa acgttatgca tgtgcttaac
    17581 attctctggg tggtattcgg cattggtctg atgctggtac tgaatttgaa gttcaaaatc
    17641 aattcaatgg tggctttgtt ggtggcggcg ctgtccgtcg ggatgctggc gggcatggat
    17701 ttgatgtcgc tgctgcacac catgaaagcg ggcttcggca acacgctggg ggaactggct
    17761 atcatcgtgg tgttcggtgc ggtcatcggt aaattgatgg tcgactccgg cgcggctcac
    17821 cagatagcac atacgctgct ggcgcgtctc ggtctgcgct atgtacagct gtcggtgatt
    17881 atcatcggcc tgatttttgg tctggcgatg ttctatgaag tggcctttat catgttagcg
    17941 ccgctggtta ttgtcattgc cgccgaagct aaaattccgt tcctgaaact ggcgatcccg
    18001 gcagtagcag ctgccactac cgcacattca ctgttcccac cgcagccggg tcctgtggcg
    18061 ctggtgaatg cttatggcgc agatatgggg atggtttata tctatggcgt actggtgacg
    18121 atcccaagtg taatctgcgc aggtctgatc ctgccgaagt tcctcggcaa tcttgagcgc
    18181 ccaacgccat cattcctgaa agcagatcaa ccggtagata tgaacaatct gccctctttc
    18241 ggcgtttcga ttctggtgcc gctgatcccg gcgatcatta tgatctccac caccatcgcc
    18301 aatatctggc tggtaaaaga tacccctgcc tgggaagtgg ttaactttat cggttcctcg
    18361 ccgattgcaa tgtttattgc gatggtggtt gcattcgtac tctttggcac cgcacgtggt
    18421 catgacatgc agtgggtgat gaacgctttt gaaagtgcgg tgaaaagcat tgcaatggtg
    18481 attctgatca tcggtgcggg tggcgtgttg aagcaaacta tcatcgacac cggcattggc
    18541 gacaccatcg gcatgttgat gtcccacggc aatatctcgc cctacattat ggcatggctg
    18601 atcactgtgc taattcgtct ggcgacgggt cagggtgtcg tttcggcgat gaccgccgcc
    18661 gggattatca gtgctgcaat ccttgatcca gcaaccggtc agctggttgg cgtgaatccg
    18721 gcgctgctgg tgctggcgac ggctgcgggt tccaacaccc tcacccacat taatgatgcc
    18781 tcattctggc tgttcaaagg ttactttgac ctgtcggtaa aagacacgtt gaaaacctgg
    18841 ggactgctgg agctggtcaa ctccgtggtt gggctgatta ttgtgttgat tattagcatg
    18901 gtagcgtaaa agaacaccag agcctgccaa tggcgggctc tgttcggatt gtcggcaaag
    18961 tgcgctttgt ttatgccaga tgcgacgctg acgcgtctta tctggcctac aaagggctaa
    19021 cgtgcaggtt tttagcttca ggtaatattg cgtacctgca ttagcaatgc cctgtgattt
    19081 ctttattgat aaacaaaagt cacgccaata atcgattgca cattccctgc agtcacctgc
    19141 cctccggtac gtgcgtaatt tgccgttaat cccagactta ccgccgaagt ccctactgct
    19201 cctaacgata ccgtgttatt cgctggaata atcgtaccgt tgcgcatcaa ctgggtgatg
    19261 ctgccaactt actgatttag tgtatgatgg tgttttgagg tgctccagtg gcttctgttt
    19321 ctatcagctg tccctcctgt tcagctactg acgggggggt gcgtaacggc aaaagcac
//
LOCUS       DADXDL010000098        18803 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.098, whole genome shotgun sequence.
ACCESSION   DADXDL010000098 DADXDL010000000
VERSION     DADXDL010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 18803)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18803)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18803
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.098"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            90..635
                     /locus_tag="IRB70_003917"
     CDS             90..635
                     /locus_tag="IRB70_003917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein"
                     /protein_id="HBC0633771.1"
                     /translation="MEVNKKQLADIFGASIRTIQNWQEQGMPVLRGGGKGNEVLYDSA
                     AVIKWYAERDAEIENEKLRREVEELRQASEADLQPGTIEYERHRLTRAQADAQELKNA
                     RDSAEVVETAFCTFVLSRIAGEIASILDGLPLSVQRRFPELENRHVDFLKRDIIKAMN
                     KAAALDELIPGLLSEYIEQSG"
     gene            610..2535
                     /locus_tag="IRB70_003918"
     CDS             610..2535
                     /locus_tag="IRB70_003918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit family protein"
                     /protein_id="HBC0633772.1"
                     /translation="MNISNSQVNRLRHFVRTGLRSLFRPEPQTAVEWADANYYLPKES
                     AYQEGRWETLPFQRAIMNAMGSDYIREVNVVKSARVGYSKMLLGVYAYFIEHKQRNTL
                     IWLPTDGDAENFMKTHVEPTIRDIPSLLALAPWYGKKHRDNTLTMKRFSNGRGFWCLG
                     GKAAKNYREKSVDVAGYDELAAFDEDIEQEGSPTFLGDKRIEGSVWPKSIRGSTPKVR
                     GTCQIERAASESPHFMRFHVACPHCGEEQYLKFGDKETPFGLKWTPDDPSSVFYLCEH
                     NACVIRQQELDFTDARYICEKTGIWTRDGILWFSSSGEEIEPPDSVTFHIWTAYSPFT
                     TWVQIVKDWMKTKGDTGKRKTFVNTTLGETWEAKIGERPDAEVMAERKEHYSAPVPDR
                     VAYLTAGIDSQLDRYEMRVWGWGPGEESWLIDRQIIMGRHDDEQTLLRVDEAINKTYT
                     RRNGAEMSISRICWDTGGIDPTIVYERSKKHGLFRVIPIKGASVYGKPVASMPRKRNK
                     NGVYLTEIGTDTAKEQIYNRFTLTPEGDEPLPGAVHFPNNPDIFDLTEAQQLTAEEQV
                     EKWVDGRKKILWDSKKRRNEALDCFVYALAALRISISRWQLDLSALLASLQEEDGAAT
                     NKKTLADYARALSGEDE"
     gene            2532..2738
                     /locus_tag="IRB70_003919"
     CDS             2532..2738
                     /locus_tag="IRB70_003919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gpW family protein"
                     /protein_id="HBC0633773.1"
                     /translation="MTRQEELAAARAALHDLMTGKRVATVQKDGRRVEFTATSVSDLK
                     KYIAELEVQTGMTQRRRGPAGFYV"
     gene            2735..4335
                     /locus_tag="IRB70_003920"
                     /pseudo
     CDS             2735..4335
                     /locus_tag="IRB70_003920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309659.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
     gene            4316..5635
                     /locus_tag="IRB70_003921"
     CDS             4316..5635
                     /locus_tag="IRB70_003921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S49 family peptidase"
                     /protein_id="HBC0633774.1"
                     /translation="MTAELRNLPHIASMAFNEPLMLEPAYARVFFCALAGQFGISRLT
                     DAVSGDSLTAGEAPAALALSGDDDGPRQARSYQVMNGIAVLPVSGTLVSRTRALQPYS
                     GMTGYNGIIARLQQAASDPMVDGILLDMDTPGGMVAGAFDCADIIARVRDIKPVWALA
                     NDMNCSAGQLLASAASRRLVTQTARTGSIGVMMAHSNYGAALEKQGVEITLIYSGSHK
                     VDGNPYSHLPDDVRETLQSRMDATRRMFAQKVSAYTGLSVQAVLDTEAAVYSGQEAID
                     AGLADELVNSTDAITVMRDALDARKSRLSGGRMTKETQSTTVSATASQADVTDVVPAT
                     EGENASAAQPDVNAQITAAVAAENSRIMGILNCEEAHGREEQARVLAETPGMTVKTAR
                     RILAAAPQSAQARSDTALDRLMQGAPAPLAAGNPASDAVNDLLNTPV"
     gene            5645..5977
                     /locus_tag="IRB70_003922"
     CDS             5645..5977
                     /locus_tag="IRB70_003922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head decoration protein"
                     /protein_id="HBC0633775.1"
                     /translation="MTSKETFTHYQPQGNSDPAHTATAPGGLSAKAPAMTPLMLDTSS
                     RKLVAWDGTTDGAAVGILAVAADQTSTTLTFYKSGTFRYEDVLWPEAASDETKKRTAF
                     AGTAISIV"
     gene            6033..7058
                     /locus_tag="IRB70_003923"
     CDS             6033..7058
                     /locus_tag="IRB70_003923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309662.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="major capsid protein"
                     /protein_id="HBC0633776.1"
                     /translation="MSMYTTAQLLAANEQKFKFDPLFLRLFFRESYPFTTEKVYLSQI
                     PGLVNMALYVSPIVSGEVIRSRGGSTSEFTPGYVKPKHEVNPQMTLRRLPDEDPQNLA
                     DPAYRRRRIIMQNMRDEELAIAQVEEMQAVSAVLKGKYTMTGEAFDPVEVDMGRSEAN
                     NITQSGGTEWSKRDKSTYDPTDDIEAYALNASGVVNIIVFDPKGWALFRSFKAVKEKL
                     DTRRGSHSELETAVKDLGKAVSYKGMYGDVAIVVYSGQYVENGVKKNFLPDNTMVLGN
                     TQARGLRTYGCIQDADAQREGINASARYPKNWVTTGDPAREFTMIQSAPLMLLADPDE
                     FVSVQLA"
     gene            7100..7498
                     /locus_tag="IRB70_003924"
     CDS             7100..7498
                     /locus_tag="IRB70_003924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-packaging protein FI"
                     /protein_id="HBC0633777.1"
                     /translation="MTKDELIARLRSLGEQLNRDVSLTGTKEELALRVAELKEELDDT
                     DETAGQDTPLSRENVLTGHENEVGSAQPDTVILDTSELVTVVALVKLHTDALHATRDE
                     PVAFVLPGTAFRVSAGVAAEMTERGLARMQ"
     gene            7510..7863
                     /locus_tag="IRB70_003925"
     CDS             7510..7863
                     /locus_tag="IRB70_003925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="head-tail joining protein"
                     /protein_id="HBC0633778.1"
                     /translation="MADFDNLFDAAIARADETIRGYMGTSATITSGEQSGAVIRGVFD
                     DPENISYAGQGVRVEGSSPSLFVRTDEVRQLRRGDTLTIGEENFWVDRVSPDDGGSCH
                     LWLGRGVPPAVNRRR"
     gene            7875..8453
                     /locus_tag="IRB70_003926"
     CDS             7875..8453
                     /locus_tag="IRB70_003926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633779.1"
                     /translation="MAIKGLEQAVENLSRISRTAVPGAAAMAINRVASSAISQSASQV
                     ARETKVRRKLVKERARLKRATVKNPQARIKVNRGDLPVIKLGNARVVLSRRRRRKKGQ
                     RSSLKGGGSVLVVGNRRIPGAFIQQLKNGRWHVMQRVAGKNRYPIDVVKIPMAVPLTT
                     AFKQNIERIRRERLPKELGYALQHQLRMVIKR"
     gene            8450..8845
                     /locus_tag="IRB70_003927"
     CDS             8450..8845
                     /locus_tag="IRB70_003927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633780.1"
                     /translation="MKHTELRAAVLDALEKHDTGATFFDGRPAVFDEADFPAVAVYLT
                     GAEYTGEELDSDTWQAELHIEVFLPAQVPDSELDAWMESRIYPVMSDIPALSDLITSM
                     VASGYDYRRDDDAGLWSSADLTYVITYEM"
     gene            8853..9593
                     /locus_tag="IRB70_003928"
     CDS             8853..9593
                     /locus_tag="IRB70_003928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633781.1"
                     /translation="MPTPNPLAPVKGAGTTLWVYNGSGDPYANPLSDNDWSRLAKVKD
                     LTPGELTAESYDDSYLDDEDADWTATGQGQKSAGDTSFTLAWMPGEQGQQALLAWFNE
                     GDTRAYKIRFPNGTVDVFRGWVSSIGKAVTAKEVITRTVKVTNVGRPSMAEDRSTVTA
                     VTGMTVTPASASVVKGKSTTLTVAFQPEGATDKSFRAVSADKTKATVSVSGMTITVNG
                     VAAGKVNIPIVSGNGEFAAVAEITVTAS"
     gene            9609..10031
                     /locus_tag="IRB70_003929"
     CDS             9609..10031
                     /locus_tag="IRB70_003929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein G"
                     /protein_id="HBC0633782.1"
                     /translation="MFLKTESFEHNGVTVTLSELSALQRIEHLALMKRQAEQAESDSN
                     RKFTVEDAIRTGAFLVAMSLWHNHPQKTKQPSMNEAVKQIEQEVLTTWPTEAISHAEN
                     VVYRLSGMYEFVVNNAPEQAEDAGPAEPVSAGKCSTVS"
     gene            10013..10447
                     /locus_tag="IRB70_003930"
     CDS             10013..10447
                     /locus_tag="IRB70_003930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail assembly protein T"
                     /protein_id="HBC0633783.1"
                     /translation="MFDGELSFALKLAREMGRPDWRAMLAGMSSTEYADWHRFYSTHY
                     FHDVLLDMHFSGLTYTVLSLFFSDPDMHPLDFSLLNRREADEEPEDDVLMQKAAGLAG
                     GVRFGPDGNEVIPTSPDVADMTEDDAMLMTVSEGIAGGVRYG"
     gene            10440..13001
                     /locus_tag="IRB70_003931"
     CDS             10440..13001
                     /locus_tag="IRB70_003931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBC0633784.1"
                     /translation="MAEPVGDLVVDLSLDAARFDEQMARVRRHFSGTESDAKKTAAVV
                     EQSLSRQALAAQKAGISVGQYKAAMRMLPAQFTDVATQLAGGQSPWLILLQQGGQVKD
                     SFGGMIPMFRGLAGAITLPMVGATSLAVATGALAYAWYQGNSTLSDFNKTLVLSGHQS
                     GLTADRMLVLSRAGQAAGLTFNQTSESLSALVKAGVSGEAQIASISQSVARFSSASGV
                     EVDKVAEAFGKLTTDPTSGLTAMARQFHNVTAEQIAYVAQLQRSGDEAGALQAANEAA
                     TKGFDDQTRRLKENMGTLETWADRTARAFKSMWDAVLDIGRPDTAQEMLIKAEAAFKK
                     ADDIWNLRKDDYFVNDEARARYWDDREKARLALEAARKKAEQQTQQDKNAQQQSDTEA
                     SRLKYTEEAQKAYERLQTPLEKYTARQEELNKALKDGKILQADYNTLMAAAKKDYEAT
                     LKKPKQSGVKVSAGDRQEDSAHAALLTLQAELRTLEKHAGANEKISQQRRDLWKAESQ
                     FAVLEEAAQRRQLSAQEKSLLAHKDETLEYKRQLAALGDKVTYQERLNALAQQADKFA
                     QQQRAKRAAIDAKSRGLTDRQAEREATEQRLKEQYGDNPLALNNVMSEQKKTWAAEDQ
                     LRGSWMAGLKSGWSEWEESATDSMSQVKSAATQTFDGIAQNMAAMLTGSEQNWRSFTR
                     SVLSMMTEILLKQAMVGIVGSIGSAIGGAVGGGASASGGTAIQAAAAKFHFATGGFTG
                     TGGKYEPAGIVHRGEFVFTKEATSRIGVGNLYRLMRGYATGGYVGTPGSMADSRSQAS
                     GTFEQNNHVVINNDGTNGQIGPAALKAVYDMARKGARDEIQTQMRDGGLFSGGGR"
     gene            12998..13327
                     /locus_tag="IRB70_003932"
     CDS             12998..13327
                     /locus_tag="IRB70_003932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633785.1"
                     /translation="MKTFRWKAKPGMDVASAPSVRKVRFGDGCSQRAPAGLNANLKTY
                     SVTLSVPREEATVLESFLEEHGGWKAFLWTPPYEWRQIKVTCAKWSSRVSMLRVEFSA
                     EFEQVVN"
     gene            13327..14025
                     /locus_tag="IRB70_003933"
     CDS             13327..14025
                     /locus_tag="IRB70_003933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage minor tail protein L"
                     /protein_id="HBC0633786.1"
                     /translation="MQDIRQETLNECTRAEQSASVVLWEIDLTEVGGERYFFCNEQNE
                     KGEPVTWQGRQYQPYPIQGSGFELNGKGTSTRPTLTVSNLYGMVTGMAEDMQSLVGGT
                     VVRRKVYARFLDAVNFVNGNSYADPEQEVISRWRIEQCSELSAVSASFVLSTPTETDG
                     AVFPGRIMLANTCTWTYRGDECGYSGPAVADEYDQPTSDITKDKCSKCLSGCKFRNNV
                     GNFGGFLSINKLSQ"
     gene            14031..14774
                     /locus_tag="IRB70_003934"
     CDS             14031..14774
                     /locus_tag="IRB70_003934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0633787.1"
                     /translation="MTQTESAILAHARRCAPAESCGFVVSTPEGERYFPCVNISGEPE
                     AYFRMSPEDWLQAEMQGEIVALVHSHPGGLPWLSEADRRLQVQSDLPWWLVCRGTIHK
                     FRCVPHLTGRRFEHGVTDCYTLFRDAYHLAGIEMPDFHREDDWWRNGQNLYLDNLEAT
                     GLYQVPLSAAQPGDVLLCCFGSSVPNHAAIYCGDGELLHHIPEQLSKRERYTDKWQRR
                     THSLWRHRAWRASAFTGICNDLAAASTFV"
     gene            14711..15343
                     /locus_tag="IRB70_003935"
     CDS             14711..15343
                     /locus_tag="IRB70_003935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000090899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail assembly protein"
                     /protein_id="HBC0633788.1"
                     /translation="MARICLYGDLQRFGRRIDLRVKTGAEAIRALATQLPAFRQKLSD
                     GWYQVRIAGRDVSTSGLTAQLHETLPDGAVIHIVPRVAGAKSGGVFQIVLGAAAIAGS
                     FFTAGATLAAWGAAIGAGGMTGILFSLGASMVLGGVAQMLAPKARTPRTQTTDNGKQN
                     TYFSSLDNMVAQGNVLPVLYGEMRVGSRVVSQEISTADEGDGGQVVVIGR"
     gene            15404..>18803
                     /locus_tag="IRB70_003936"
     CDS             15404..>18803
                     /locus_tag="IRB70_003936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host specificity protein J"
                     /protein_id="HBC0633789.1"
                     /translation="MGKGSSKGHTPREAKDNLKSTQLLSVIDAISEGPVEGPVDGLKS
                     VLLNSTPVLDSEGNTNISGVTVVFRTGEQEQSPPEGFESSGSETVLGTEVKYDTPITR
                     TITSANIDRLRFTFGVQALVETTSKGDRNPSEVRLLVQIQRNGGWVTEKDITIKGKTT
                     SQYLASVVVDNLPPRPFNIRMRRMTPDSTTDQLQNKTLWSSYTEIIDVKQCYPNTALV
                     GVQVDSEQFGSQQVSRNYHLRGRILQVPSNYNPQTRQYSGIWDGTFKPAYSNNMAWCL
                     WDMLTHPRYGMGKRLGAADVDKWALYVIGQYCDQSVPDGFGGTEPRITCNAYLTTQRK
                     AWDVLSDFCSAMRCMPVWNGQTLTFVQDRPSDKVWTYNRSNVVMPDDGAPFRYSFSAL
                     KDRHNAVEVNWIDPDNGWETATELVEDTQAIARYGRNVTKMDAFGCTSRGQAHRAGLW
                     LIKTELLETQTVDFSVGAEGLRHVPGDVIEICDDDYVGISTGGRVLAVNSQTRTLTLD
                     REITLPSSGTTLISLVDGSGNPVSVEVQSVTDGLKVKVNRVPDGVAEYSVWGLKLPTL
                     RQRLFRCVSIRENDDGTYAITAVQHVPEKEAIVDNGAHFDGDQSGTVNGVTPPAVQHL
                     TAEVTADSGEYQVLARWDTPKVVKGVSFLLRLTVTADDGSERLVSTARTTETTYRFTQ
                     LALGNYRLTVRAVNAWGQQGDPASVSFRIAAPAAPSRIELTPGYFQITATPHLAVYDP
                     TVQFEFWFSEKRIADIRQVETSARYLGTALYWIAASINIKPGHDYYFYIRSVNTVGKS
                     AFVEAIGRASDDAEGYLDFFKGEIGKTHLAQELWTQIDNGQLAPDLAEIRTSITDVSN
                     EITQTVNKKLEDQSAAIQQIQKVQVDTNNNLNSMWAVKLQQMQDGRLYIAGIGAGIEN
                     TPDGMQSQVLLAADRIAMVNPANGNTKPMFVGQGDQIFMNEVFLKYLTAPTITSGGNP
                     PAFSLTPDGRLTAKNADISGNVNANSGTLNNVTINENCRVLGKLSANQIEGDLVKTVG
                     KAFPRDSRAPERWPSGTITVRVYDDQPFDRQIVIPAVAFSGAKHEQDHTDIYSSCRLI
                     VRKNGAEIYNRTALDNTLIYTGVIDMPAGSGVMTLEFSVSAWLVN"
BASE COUNT         4292 a         4786 c         5927 g         3798 t
ORIGIN      
        1 ctctgaaaag aaaggaaacg acaggtgctg aaagcgagct ttttggcctc tgtcgtttcc
       61 tttctctgtt tttgtccgtg gaatgaacaa tggaagtcaa caaaaagcag ctggctgaca
      121 ttttcggtgc gagtatccgt accattcaga actggcagga acagggaatg cccgttctgc
      181 gaggcggtgg caagggtaat gaggtgcttt atgactctgc cgccgtcata aaatggtatg
      241 ccgaaaggga tgctgaaatt gagaacgaaa agctgcgccg ggaggttgaa gaactgcggc
      301 aggccagcga ggcagatctc cagccaggaa ctattgagta cgaacgccat cgacttacgc
      361 gtgcgcaggc cgacgcacag gaactgaaga atgccagaga ctccgctgaa gtggtggaaa
      421 ccgcattctg tactttcgtg ttgtcgcgga tcgcaggtga aattgccagt attctcgacg
      481 ggctccccct gtcggtgcag cggcgttttc cggaactgga aaaccgacat gttgatttcc
      541 tgaaacggga tattatcaaa gccatgaaca aagcagccgc gctggatgaa ctgataccgg
      601 ggttgctgag tgaatatatc gaacagtcag gttaacaggc tgcggcattt tgtccgcacc
      661 gggcttcgct cactgttcag gccggagcca cagaccgccg ttgaatgggc ggatgctaat
      721 tactatctcc cgaaagaatc cgcataccag gaagggcgct gggaaacact gccctttcag
      781 cgggccatca tgaatgcgat gggcagcgac tacatccgtg aggtgaatgt ggtgaagtct
      841 gcccgtgtcg gttattccaa aatgctgctg ggtgtttatg cctactttat agagcataag
      901 cagcgcaaca cccttatctg gttgccgacg gatggtgatg ccgagaactt tatgaaaacc
      961 cacgttgagc cgaccatccg cgatattccg tcgctgctgg cgctggctcc gtggtatggc
     1021 aaaaagcacc gggataacac gctcactatg aagcgttttt ccaatggtcg tggcttctgg
     1081 tgcctgggcg gtaaagcggc aaaaaactac cgtgaaaagt cagtggatgt ggcgggttat
     1141 gatgaacttg ctgcctttga tgaggatatt gaacaggaag gctctccgac gttcctgggt
     1201 gacaagcgta ttgaaggctc ggtctggcca aagtccatcc gtggctccac gccaaaagtg
     1261 agaggcacct gtcagattga gcgtgcagcc agtgaatccc cgcattttat gcgttttcat
     1321 gttgcctgcc cgcattgcgg ggaggagcag tatcttaaat ttggcgacaa agagacgccg
     1381 tttggcctca aatggacgcc ggatgacccc tccagcgtgt tttatctctg cgagcataat
     1441 gcctgcgtca tccgccagca ggagctggac tttactgatg cccgttatat ctgcgaaaag
     1501 accgggatct ggacccgtga tggcattctc tggttttcgt catccggtga agagattgag
     1561 ccacctgaca gtgtgacctt tcacatctgg acagcgtaca gcccgttcac cacctgggtg
     1621 cagattgtca aagactggat gaaaacgaaa ggggatacgg gaaaacgtaa aaccttcgta
     1681 aacaccacgc tcggtgagac gtgggaggcg aaaattggcg aacgtccgga tgctgaagtg
     1741 atggcagagc ggaaagagca ttattcagcg cccgttcctg accgtgtggc ttacctgacc
     1801 gccggtatcg actcccagct ggaccgctac gaaatgcgcg tatggggatg ggggccgggt
     1861 gaggaaagct ggctgattga ccggcagatt attatgggcc gccacgacga tgaacagacg
     1921 ctgctgcgtg tggatgaggc catcaataaa acctataccc gccggaatgg tgcagaaatg
     1981 tcgatatccc gtatctgctg ggatactggc gggattgacc cgaccattgt gtatgaacgc
     2041 tcgaaaaaac atgggctgtt ccgggtgatc cccattaaag gggcatccgt ctacggaaag
     2101 ccggtggcca gcatgccacg taagcgaaac aaaaacgggg tttaccttac cgaaatcggt
     2161 acggataccg cgaaagagca gatttataac cgcttcacac tgacgccgga aggggatgaa
     2221 ccgcttcccg gtgccgttca cttcccgaat aacccggata tttttgatct gaccgaagcg
     2281 cagcagctga ctgctgaaga gcaggtcgaa aaatgggtgg atggcaggaa aaaaatactg
     2341 tgggacagca aaaagcgacg caatgaggcg ctcgactgct tcgtttatgc gctggcggcg
     2401 ctgcgcatca gtatttcccg ctggcagctg gatctcagtg cactgctggc gagcctgcag
     2461 gaagaggatg gtgcagcaac caacaagaaa acactggcag attacgcccg tgccttatcc
     2521 ggagaggatg aatgacgcga caggaagaac ttgccgctgc ccgtgcggca ctgcatgacc
     2581 tgatgacagg aaaacgggtg gcaacggtac agaaagacgg acggagagtg gagtttacgg
     2641 ccacttccgt gtctgacctg aaaaaataca ttgcggagct ggaagtgcag accggcatga
     2701 cacagcgacg caggggacct gcaggatttt atgtatgaaa acgtccacca ttcccatcct
     2761 tctggggccg gacggcatga catcgctgcg tgaatatgcc ggttatcacg gcggtggcag
     2821 cggatttggt gggcagttgc gggcgtggaa cccaccgagt gaaagtgtgg atgcagccct
     2881 gctgcccaac tttacccgtg gcaatgcccg cgcggacgat ctggtacgca ataacggcta
     2941 tgccgccaac gccatccagt tgcatcagga tcatatcgtc gggtcttttt tccggctcag
     3001 tcatcgccca agctggcgct atctgggcat cggggaggaa gaagcccgtg ccttttcccg
     3061 cgaggttgaa gcggcatgga aagagtttgc cgaggatgac tgctgctgca ttgacgttga
     3121 gcgaaaacgc acgtttacat gatgattcgg gaaggtgtgg ccatgcacgc ctttaacggt
     3181 gaactgttcg ttcaggccac ctgggatacc agcccgtcgc gactgttccg gacacagttc
     3241 cggatggtca gtccgaagcg tatcagcaac ccgaacaata ccggcgacag ccggaactgc
     3301 cgtgccggtg tgcagattaa tgacagcggc gcggcgctgg gatattacgt cagcgaggac
     3361 ggctatcctg gctggatgcc gcagaaatgg acatggatac cccgtgagtt acccggcggg
     3421 cgcgcctcgt tcattcacgt ttttgaaccc gtggaggacg ggcagacccg cggtgcaaat
     3481 gtgttttaca gcgtaatgga gcagatgaag atgctcgaca cgctgcagaa cacgcagctg
     3541 cagagcgcca ttgtgaaggc gatgtatgcc gccaccattg aaagtgagct ggatacgcag
     3601 tcagcgatgg attttattct gggcgcgaac agtcaggagc agcgggaaag gctgacgggc
     3661 tggattggtg aaattgccgc gtattacgcc gcagcaccgg tccgtctggg aggcgcaaaa
     3721 gtgccgcacc tgatgccggg ggactcactg aacctgcaga cggctcagga tacggataac
     3781 ggctactccg tgtttgagca gtcactgttg cggtatatcg ctgccgggct gggtgtctcg
     3841 tatgagcagc tttcccggaa ttacgcccag atgagctact ccacggcacg ggccagtgcg
     3901 aacgagtcgt gggcgtactt tatggggcgg cgaaaattcg tcgcatcccg tcaggcgagc
     3961 cagatgtttc tgtgctggct tgaagaggcc atcgttcgcc gcgtggtgac gttaccttca
     4021 aaagcgcgct tcagctttca ggaagcccgc agtgcctggg ggaactgcga ctggataggc
     4081 tccggtcgta tggccatcga tggtctgaaa gaagttcagg aagcggtgat gctgatagaa
     4141 gccggactga gcacctacga gaaagagtgc gcgaaacgcg gtgacgacta tcaggaaatt
     4201 tttgcccagc aggtccgtga aacgatggag cgccgtgcag ccggtcttaa accgcccgcc
     4261 tgggcggctg cggcatttga atctggactg cgacaatcaa cagaggagga gaagagtgac
     4321 agcagagctg cgtaatctcc cgcatattgc cagcatggct tttaatgagc cgctgatgct
     4381 tgaacccgcc tatgcgcggg ttttcttttg tgcgcttgca ggccagtttg ggatcagccg
     4441 cctgacggat gcagtatccg gcgacagcct gactgccgga gaggcacccg cggcgctggc
     4501 gttatccggt gatgatgacg gaccacgaca ggcccgcagt tatcaggtca tgaacggcat
     4561 cgccgtgctg ccggtgtccg gtacgctggt cagccggacg cgggcgctgc agccgtattc
     4621 gggaatgacc ggttacaacg gcattatcgc ccgtctgcaa caggctgcca gcgatccgat
     4681 ggtggacggc attctgctgg atatggacac accgggcggg atggtggcgg gagcatttga
     4741 ctgtgctgac atcatcgccc gtgtgcgaga cataaaaccg gtatgggcgc tggccaacga
     4801 catgaactgc agtgcaggtc agctgcttgc cagcgccgcc tcccggcgtc tggtcacgca
     4861 gaccgcccgg acaggctcca tcggcgtcat gatggctcac agtaattacg gtgctgcgct
     4921 ggagaaacag ggcgtggaaa tcacgctgat ttacagcggc agccataagg tggatggcaa
     4981 cccctacagc catctaccgg atgatgtccg ggaaacactg cagtcccgga tggatgcaac
     5041 ccgccggatg tttgcacaga aggtgtcggc atataccggc ctgtccgtgc aggctgtgct
     5101 ggataccgag gctgcagtgt acagcggtca ggaggccatt gatgccggac tggctgatga
     5161 acttgttaac agcaccgatg cgatcaccgt catgcgtgat gcactggatg cacgtaaatc
     5221 ccgtctctca ggagggcgaa tgaccaaaga gactcaatca acaactgttt cagccactgc
     5281 ttcgcaggct gacgttactg acgtggtgcc agcgacggag ggcgagaacg ccagcgcggc
     5341 gcagccggac gtgaacgcgc agatcaccgc agcggttgcg gcagaaaaca gccgcattat
     5401 ggggatcctc aactgtgagg aggctcacgg acgcgaagaa caggcacgcg tgctggcaga
     5461 aacccccggt atgaccgtga aaacggcccg ccgcattctg gccgcagcac cacagagtgc
     5521 acaggcgcgc agtgacactg cgctggatcg tctgatgcag ggggcaccgg caccgctggc
     5581 tgcaggtaac ccggcatctg atgccgttaa cgatttgctg aacacaccag tgtaagggat
     5641 gtttatgacg agcaaagaaa cctttaccca ttaccagccg cagggcaaca gtgacccggc
     5701 tcataccgca accgcgcccg gcggattgag tgcgaaagcg cctgcaatga ccccgctgat
     5761 gctggacacc tccagccgta agctggttgc gtgggatggc accaccgacg gtgctgccgt
     5821 tggcattctt gcggttgctg ctgaccagac cagcaccacg ctgacgttct acaagtccgg
     5881 cacgttccgt tatgaggatg tgctctggcc ggaggctgcc agcgacgaga cgaaaaaacg
     5941 gaccgcgttt gccggaacgg caatcagcat cgtttaactt tacccttcat cactaaaggc
     6001 cgcctgtgcg gcttttttta cgggattttt ttatgtcgat gtacacaacc gcccagctgc
     6061 tggcggcaaa tgagcagaaa tttaagtttg atccgctgtt tctgcgtctc tttttccgtg
     6121 agagctatcc cttcactacg gagaaagtct atctctcaca aattccggga ctggtaaaca
     6181 tggcgctgta cgtttcgccg attgtttccg gtgaggttat ccgttcccgt ggcggctcca
     6241 cctctgaatt tacgccggga tatgtcaaac ccaagcatga agtgaatccg cagatgaccc
     6301 tgcgtcgcct gccggatgaa gatccgcaga atctggcgga cccggcttac cgccgccgtc
     6361 gcatcatcat gcagaacatg cgtgacgaag agctggccat tgctcaggtc gaagagatgc
     6421 aggcagtttc tgccgtgctt aagggcaaat ataccatgac cggtgaagcc ttcgatccgg
     6481 ttgaggtgga tatgggccgc agtgaggcga ataacatcac gcagtccggc ggcacggagt
     6541 ggagcaagcg tgacaagtcc acgtatgacc cgaccgacga tatcgaagcc tacgcgctga
     6601 acgccagcgg tgtggtgaat atcatcgtgt ttgatccgaa aggctgggcg ctgttccgtt
     6661 ccttcaaagc cgtcaaggag aagctggata cccgtcgcgg ctctcattcc gagctggaga
     6721 cagcggtaaa agacctgggc aaagcggtgt cctataaggg aatgtatggc gatgtggcca
     6781 tcgtcgtgta ttccggacag tacgtggaaa acggcgtcaa aaagaacttc ctgccggaca
     6841 acacgatggt gctggggaac actcaggctc gcggtctgcg cacctatggc tgcattcagg
     6901 atgcggacgc acagcgcgaa ggcattaacg cctctgcccg ttacccgaaa aactgggtga
     6961 ctaccggcga tccggcgcgt gagttcacca tgattcagtc agcaccgctg atgctgctgg
     7021 ctgatcctga tgagttcgtg tccgttcaac tggcgtaatc atggcccttc ggggccattg
     7081 tttctctgtg gaggagtcca tgacgaaaga tgaactgatt gcccgtctcc gctcgctggg
     7141 tgaacaactg aaccgtgatg tcagcctgac ggggacgaaa gaagaactgg cgctccgtgt
     7201 ggcagagctg aaagaggagc ttgatgacac ggatgaaact gccggtcagg acacccctct
     7261 cagccgggaa aatgtgctga ccggacatga aaatgaggtg ggatcagcgc agccggatac
     7321 cgtgattctg gatacgtctg aactggtcac ggtcgtggca ctggtgaagc tgcatactga
     7381 tgcacttcac gccacgcggg atgaacctgt ggcatttgtg ctgccgggaa cggcgtttcg
     7441 tgtctctgcc ggtgtggcag ccgaaatgac agagcgcggc ctggccagaa tgcaataacg
     7501 ggaggcgctg tggctgattt cgataacctg ttcgatgctg ccattgcccg cgccgatgaa
     7561 acgatacgcg ggtacatggg aacgtcagcc accattacat ccggtgagca gtcaggtgcg
     7621 gtgatacgtg gtgtttttga tgaccctgaa aatatcagct atgccggaca gggcgtgcgc
     7681 gttgaaggct ccagcccgtc cctgtttgtc cggactgatg aggtgcggca gctgcggcgt
     7741 ggagacacgc tgaccatcgg tgaggaaaat ttctgggtag atcgggtttc gccggatgat
     7801 ggcggaagct gtcatctctg gcttggacgg ggcgtaccgc ctgccgttaa ccgtcgccgc
     7861 tgaaaggggg atgtatggcc ataaaaggtc ttgagcaggc cgttgaaaac ctcagccgta
     7921 tcagcagaac ggcggtgccc ggtgccgccg caatggccat taaccgagtt gcttcatccg
     7981 cgatatcgca gtcggcgtca caggttgccc gtgagacaaa ggtacgccgg aaactggtaa
     8041 aggaaagggc caggctgaaa agggccacgg tcaaaaatcc gcaggccaga atcaaggtta
     8101 accgggggga tttgcccgta atcaagctgg gtaatgcgcg ggttgtcctt tcgcgccgca
     8161 ggcgtcgtaa aaaggggcag cgttcatccc tgaaaggtgg cggcagcgtg cttgtggtgg
     8221 gaaaccgtcg tattcccggc gcgtttattc agcaactgaa aaatggccgg tggcatgtca
     8281 tgcagcgtgt ggccgggaaa aaccgttacc ccattgatgt ggtgaaaatt ccgatggcgg
     8341 tgccgctgac cacggcgttt aaacagaata ttgagcggat acggcgtgaa cgtcttccga
     8401 aagagctggg ctatgcgctg cagcatcaac tgagaatggt aataaagcga tgaaacatac
     8461 tgaactccgc gcagccgtac tggatgcact ggagaagcat gacaccgggg cgacgttttt
     8521 tgatggtcgc cccgctgttt ttgatgaggc ggattttccg gcagttgccg tttatctcac
     8581 cggcgctgaa tacacgggcg aagagctgga cagcgatacc tggcaggcgg agctgcatat
     8641 cgaagttttc ctgcctgctc aggtgccgga ttcagagctg gatgcgtgga tggagtcccg
     8701 gatttatccg gtgatgagcg atatcccggc actgtcagat ttgatcacca gtatggtggc
     8761 cagtggctat gactaccggc gcgacgatga tgcgggcctg tggagttcag ccgatctgac
     8821 ttatgtcatt acctatgaaa tgtgaggacg atatgccaac accaaatcct ctggcaccgg
     8881 tgaaaggggc cgggaccacc ctgtgggttt ataacgggag cggcgaccct tatgcaaacc
     8941 cgctttcaga caatgactgg tcgcgtctgg caaaggttaa agacctgacg cccggcgaac
     9001 tgaccgctga gtcctatgac gacagttatc tcgatgatga agatgcggac tggaccgcga
     9061 ccggacaggg gcagaaatcc gccggagata ccagcttcac gctggcgtgg atgcccggag
     9121 agcaggggca gcaggcgctg ctggcgtggt ttaatgaagg tgatacccgt gcctataaaa
     9181 tccgcttccc gaacggcacg gtcgatgtgt tccgcggctg ggtcagcagt atcggtaagg
     9241 cggtgacggc gaaggaagtg atcacccgca cggtgaaagt caccaatgtg ggacgtccgt
     9301 cgatggcaga agatcgcagc acggtaacag cggtaaccgg tatgaccgtg acgccagcca
     9361 gcgcttccgt agtgaaaggg aagagcacca cgctgaccgt ggcattccag ccggaaggcg
     9421 caaccgacaa gagcttccgt gcggtgtcag cggataaaac aaaagccacc gtgtcggtca
     9481 gtggtatgac catcaccgtg aatggcgttg ctgcaggcaa ggtcaacatt ccgattgtat
     9541 ccggtaatgg tgagtttgct gcggttgcag aaatcaccgt caccgccagt taatccggag
     9601 agtcagagat gttcctgaaa accgaatcat ttgaacataa cggtgtgacc gtcacgcttt
     9661 ctgaactgtc agccctgcag cgtattgagc atctcgccct gatgaaacgg caggcagaac
     9721 aggcggagtc agacagcaac cggaagttta ctgtggaaga cgccatcaga accggcgcgt
     9781 ttctggtggc gatgtccctg tggcataacc atccgcagaa gacaaagcag ccttccatga
     9841 atgaagccgt taaacagatt gagcaggaag tgcttaccac ctggcccaca gaggcaattt
     9901 ctcatgctga aaacgtggtg taccggctgt ctggtatgta tgagtttgtg gtgaataatg
     9961 cccctgaaca ggcagaggac gccgggcccg cagaacctgt ttctgcggga aagtgttcga
    10021 cggtgagctg agttttgccc tgaaactggc gcgtgagatg gggcgacccg actggcgtgc
    10081 catgcttgcc gggatgtcat ccacggagta tgccgactgg caccgctttt acagtaccca
    10141 ttattttcat gatgttctgc tggatatgca cttttccggg ctgacgtaca ccgtgctcag
    10201 cctgtttttc agcgatccgg atatgcatcc gctggatttc agtctgctga accggcgcga
    10261 ggctgacgaa gagcctgaag atgatgtgct gatgcagaaa gcggcagggc ttgccggagg
    10321 tgtccgcttt ggcccggacg ggaatgaagt tatccctact tccccggatg tggcggacat
    10381 gacggaggat gacgcaatgc tgatgacagt atcagaaggg atcgcaggag gagtccggta
    10441 tggctgaacc ggtaggcgat ctggtcgttg atttgagtct ggatgcggcc agatttgacg
    10501 agcagatggc cagagtcagg cgtcattttt ccggtacgga aagtgatgcg aaaaaaacag
    10561 cggcagtcgt tgaacagtcg ctgagccgac aggcgctggc tgcacagaaa gcggggattt
    10621 ccgtcgggca gtataaagct gccatgcgta tgctgcctgc gcagttcact gacgtggcca
    10681 cgcagcttgc aggcgggcaa agtccgtggc tgatcctgct gcaacagggg gggcaggtga
    10741 aggactcctt cggcgggatg atccccatgt tcagggggct tgccggtgcg atcaccctgc
    10801 cgatggtggg ggccacctcg ctggcggtgg cgaccggtgc gctggcgtat gcctggtatc
    10861 agggcaactc aaccctgtcc gatttcaaca aaacgctggt cctttccggt catcagtcgg
    10921 gtctgacggc agatcgtatg ctggtcctgt ccagagccgg gcaggcggca gggctgacgt
    10981 ttaaccagac cagcgagtca ctcagcgcac tggttaaggc gggggtaagc ggtgaggctc
    11041 agattgcgtc catcagccag agtgtggcgc gtttctcctc tgcatccggc gtggaggtgg
    11101 acaaggtcgc tgaagccttc gggaagctga ccacagaccc gacgtcgggg ctgacggcga
    11161 tggcacgcca gttccataac gtgacggcgg agcagattgc gtatgttgct cagttgcagc
    11221 gttccggcga tgaagccggg gcattgcagg cggcgaacga ggccgcaacg aaagggtttg
    11281 atgaccagac ccgccgcctg aaagagaaca tgggcacgct ggagacctgg gcagacagga
    11341 ctgcgcgggc attcaaatcc atgtgggatg cggtgctgga tattggtcgt cctgataccg
    11401 cgcaggagat gctgattaag gcagaggctg cgtttaagaa agcagacgac atctggaatc
    11461 tgcgcaagga tgattatttt gttaacgatg aagcgcgggc gcgttactgg gatgatcgtg
    11521 aaaaggcccg tcttgcgctt gaagccgccc gaaagaaggc tgagcagcag actcaacagg
    11581 acaaaaatgc gcagcagcag agcgataccg aagcgtcacg gctgaaatat accgaagagg
    11641 cgcagaaggc ttacgaacgg ctgcagacgc cgctggagaa atataccgcc cgtcaggaag
    11701 aactgaacaa ggcactgaaa gacgggaaaa tcctgcaggc agattacaac acgctgatgg
    11761 cggcggcgaa aaaggattat gaagcgacgc tgaaaaagcc gaaacagtcc ggcgtgaaag
    11821 tgtctgcggg cgatcgtcag gaagacagtg ctcatgctgc cctgctgacg cttcaggcag
    11881 aactccggac gctggagaag catgccggag cgaatgagaa aatcagccag cagcgccggg
    11941 atttgtggaa ggcagaaagt cagttcgcgg tactggagga ggcggcacaa cgtcgccagc
    12001 tgtccgcaca ggagaaatcc ctgctggcgc ataaagatga gacgctggag tacaaacgcc
    12061 agctggctgc acttggcgac aaggttacgt atcaggagcg cctgaacgcg ctggcgcagc
    12121 aggcggataa attcgcacag cagcaacggg caaaacgggc cgccattgat gcgaaaagcc
    12181 gggggctgac tgaccggcag gcagaacggg aagccacgga acagcgcctg aaggaacagt
    12241 atggcgataa tccgctggcg ctgaataacg tcatgtcaga gcagaaaaag acctgggcgg
    12301 ctgaagacca gcttcgcggg agctggatgg caggcctgaa gtccggctgg agtgagtggg
    12361 aagagagcgc cacggacagt atgtcgcagg taaaaagtgc agccacgcag acctttgatg
    12421 gtattgcaca gaatatggcg gcgatgctga ccggcagtga gcagaactgg cgcagcttca
    12481 cccgttccgt gctgtccatg atgacagaaa ttctgcttaa gcaggcaatg gtggggattg
    12541 tcgggagtat cggcagcgcc attggcgggg ctgttggtgg cggcgcatcc gcgtcaggcg
    12601 gtacagccat tcaggccgct gcggcgaaat tccattttgc aaccggagga tttacgggaa
    12661 ccggcggcaa atatgagcca gcggggattg ttcaccgtgg tgagtttgtc ttcacgaagg
    12721 aggcaaccag ccggattggc gtggggaatc tttaccggct gatgcgcggc tatgccaccg
    12781 gcggttatgt cggtacaccg ggcagcatgg cagacagccg gtcgcaggcg tccgggacgt
    12841 ttgagcagaa taaccatgtg gtgattaaca acgacggcac gaacgggcag ataggtccgg
    12901 ctgctctgaa ggcggtgtat gacatggccc gcaagggtgc ccgtgatgaa attcagacac
    12961 agatgcgtga tggtggtctg ttctccggag gtggacgatg aaaaccttcc gctggaaagc
    13021 gaaacccggt atggatgtgg cttcggcccc ttctgtaaga aaggtgcgct ttggtgatgg
    13081 ctgttcccag cgagcgcctg ccgggctgaa tgccaacctg aaaacgtaca gcgtgacgct
    13141 ttctgtcccc cgtgaggagg ccacggtact ggagtcgttt ctggaagagc acgggggctg
    13201 gaaagccttt ctgtggacgc cgccttatga gtggcggcag ataaaggtga cctgcgcaaa
    13261 atggtcgtcg cgggtcagta tgctgcgtgt tgagttcagc gcagagtttg aacaggtggt
    13321 gaactgatgc aggatatccg gcaggaaaca ctgaatgaat gcacccgtgc ggagcagtcg
    13381 gccagcgtgg tgctctggga aatcgacctg acagaggtcg gtggagaacg ttattttttc
    13441 tgtaatgagc agaacgaaaa aggtgagccg gtcacctggc aggggcgaca gtatcagccg
    13501 tatcccattc aggggagcgg ttttgaactg aatggcaaag gcaccagtac gcgccccacg
    13561 ctgacggttt ctaacctgta cggtatggtc accgggatgg cggaagatat gcagagtctg
    13621 gtcggcggaa cggtggtccg gcgtaaggtt tacgcccgtt ttctggatgc ggtgaacttc
    13681 gtcaacggaa acagttatgc cgatccggag caggaggtga tcagccgctg gcgcattgag
    13741 cagtgcagcg aactgagcgc ggtgagtgcc tcctttgtac tgtccacgcc gacggaaacg
    13801 gatggcgctg tttttccggg acgtatcatg ctggccaaca cctgcacctg gacctatcgc
    13861 ggtgacgagt gcggttatag cggtccggcg gtcgcggatg aatatgacca gccaacgtcc
    13921 gatatcacga aggataaatg cagcaaatgc ctgagcggtt gtaagttccg caataacgtc
    13981 ggcaactttg gcggcttcct ttccattaac aaactttcgc agtaaatccc atgacacaga
    14041 cagaatcagc gattctggcg cacgcccggc gatgtgcgcc agcggagtcg tgcggcttcg
    14101 tggtaagcac gccggagggg gaaagatatt tcccctgcgt gaatatctcc ggtgagccgg
    14161 aggcgtattt ccgtatgtcg ccggaagact ggctgcaggc agaaatgcag ggtgagattg
    14221 tggcgctggt ccacagccac cccggtggtc tgccctggct gagtgaggcc gaccggcggc
    14281 tgcaggtgca gagtgatttg ccgtggtggc tggtctgccg ggggacgatt cataagttcc
    14341 gctgtgtgcc gcatctcacc gggcggcgct ttgagcacgg tgtgacggac tgttacacac
    14401 tgttccggga tgcttatcat ctggcgggga ttgagatgcc ggactttcat cgtgaggatg
    14461 actggtggcg taacggccag aatctctatc tggataatct ggaggcgacg gggctgtatc
    14521 aggtgccgtt gtcagcggca cagccgggcg atgtgctgct gtgctgtttt ggttcatcgg
    14581 tgccgaatca cgccgcaatt tactgcggcg acggcgagct gctgcaccat attcctgaac
    14641 aactgagcaa acgagagagg tacaccgaca aatggcagcg acgcacacac tccctctggc
    14701 gtcaccgggc atggcgcgca tctgccttta cggggatttg caacgatttg gccgccgcat
    14761 cgaccttcgt gtgaaaacgg gggctgaagc catccgcgca ctggccacac agctcccggc
    14821 gtttcgtcag aaactgagcg acggctggta tcaggtacgg attgccgggc gggacgtcag
    14881 cacgtccggg ttaacggcgc agttacatga gactctgcct gatggcgctg tgattcatat
    14941 tgttcccaga gtcgccgggg ccaagtcagg tggcgtattc cagattgtcc tgggagcagc
    15001 cgccattgcc ggatcattct ttactgccgg agccaccctt gcagcatggg gggcagccat
    15061 tggggccggt ggtatgaccg gcatcctgtt ttctctcggt gccagtatgg tgctcggtgg
    15121 tgtggcgcag atgctggcac cgaaagccag aactccccgt acacagacaa cggataacgg
    15181 caaacagaac acctatttct cctcactgga taacatggtt gcccagggca atgttctgcc
    15241 tgttctgtac ggtgaaatgc gcgtggggtc acgcgtggtt tctcaggaga tcagcacggc
    15301 agacgaaggg gatggtggtc aggttgtggt gattggtcgc tgatgcaaaa tgttttatgt
    15361 gaaaccgcct gcgggcggtt ttgtcgttta tggagcgtga ggaatgggta aaggcagcag
    15421 taaggggcat accccgcgcg aagcgaagga caacctgaag tccacgcagc tgctgagtgt
    15481 gatcgatgcc atcagcgaag ggccggttga aggtccggtg gacggattaa aaagcgtgct
    15541 gctgaacagt acgccggtgc tggacagtga ggggaatacc aatatctccg gcgtcacggt
    15601 ggtgttccgg accggtgagc aggagcagtc accgccggag ggatttgaat cctccggctc
    15661 cgagacggtg ctgggtacgg aagtgaaata tgacacgccg atcacccgga ccatcacgtc
    15721 ggcaaacatc gaccgtctgc gctttacctt cggtgtacag gcactggtgg aaaccacctc
    15781 aaagggggac cggaatccgt cggaagtccg cctgctggtt cagatacagc gtaatggtgg
    15841 ctgggtgacg gaaaaagaca tcaccattaa gggcaaaacc acctcgcagt atctggcctc
    15901 ggtggtggtg gataacctgc cgccgcgccc gttcaatatc cggatgcgca ggatgacgcc
    15961 ggacagcacc acagaccagc tgcagaacaa aacgctctgg tcgtcataca ccgaaatcat
    16021 cgatgtgaaa cagtgctacc cgaacacggc actggtcggc gtacaggtgg attcggagca
    16081 gttcggcagc cagcaggtga gccgtaatta tcatctgcgc gggcgtattc tgcaggtgcc
    16141 gtcgaactat aacccgcaga ctcggcaata cagcggtatc tgggacggaa cgtttaagcc
    16201 agcatacagc aataacatgg cctggtgtct gtgggatatg ctgacccatc cacgctacgg
    16261 catggggaaa cgtcttggtg cggcggatgt ggacaaatgg gcgctgtatg tcatcggcca
    16321 gtactgcgac cagtcagtgc cggacggctt tggcggcacg gagccgcgca tcacctgtaa
    16381 tgcgtacctg accacacagc gcaaggcgtg ggatgtgctc agtgatttct gctcggcgat
    16441 gcgctgtatg ccggtatgga acgggcagac gctgacgttc gtgcaggacc gaccgtcgga
    16501 taaggtgtgg acctataacc gcagtaatgt ggtgatgccg gatgatggcg cgccgttccg
    16561 ctacagcttc agcgccctga aggaccgcca taatgccgtt gaggtgaact ggattgaccc
    16621 ggacaacggc tgggagacgg cgacagagct tgttgaagat acgcaggcca ttgcccgtta
    16681 cggtcgtaat gtcacgaaga tggatgcctt tggctgtacc agccgggggc aggcacaccg
    16741 cgccgggctg tggctgatta aaacggaact gctggagacg cagaccgtgg atttcagcgt
    16801 gggtgctgaa gggcttcgcc atgtaccggg cgatgtcatt gaaatctgcg atgatgacta
    16861 tgtcggtatc agcaccggtg gtcgcgtgct ggcggtgaac agccagaccc ggacgctgac
    16921 gctcgaccgt gaaatcacgc tgccatcctc cggtaccacg ctgataagcc tggttgacgg
    16981 aagtggtaat ccggtcagcg tggaggttca gtccgtcacc gacggactta aggtgaaagt
    17041 gaaccgggtt cctgacggcg ttgcagaata cagtgtgtgg gggctgaagc tgccgacgct
    17101 gcgccagcgc ctgttccgct gtgtgagtat ccgtgagaac gacgacggca cgtatgccat
    17161 caccgccgtg cagcatgtgc cggaaaaaga ggccatcgtg gataacgggg cgcactttga
    17221 cggcgaccag agcggcacgg tgaatggtgt cacgccgcca gcggtgcagc acctgactgc
    17281 cgaagtcacc gcagacagcg gggaatatca ggtgctggcg cgctgggaca caccgaaggt
    17341 ggtgaagggc gtgagcttcc tgctccgtct gaccgtaaca gcggacgacg gcagtgagcg
    17401 gctggtcagc acggcccgga cgacggaaac cacataccgc ttcacacaac tggcgttggg
    17461 gaactacagg ctgacagtcc gggcggtaaa tgcgtgggga cagcagggcg atccggcatc
    17521 ggtatcgttc cggattgccg caccggcagc gccgtctcgg attgagctga caccgggcta
    17581 ttttcagata accgccacgc cgcatcttgc ggtttatgac ccgacggtac agtttgagtt
    17641 ctggttctcg gaaaaacgga ttgcggatat caggcaggtt gaaaccagcg cgcgttatct
    17701 tggtacggca ctgtactgga tagccgccag tatcaatatc aaaccgggcc atgattatta
    17761 cttttatatc cgcagtgtga atactgttgg caaatcggca ttcgtggagg ctatcggtcg
    17821 ggcgagcgat gatgcggaag gttacctgga ttttttcaaa ggagagatag ggaaaacaca
    17881 tctggctcag gagctgtgga cgcagattga taacggtcag cttgcgcctg acctggctga
    17941 aatcaggacg tccattacgg atgtcagcaa tgaaatcacg cagactgtca ataagaaact
    18001 ggaagaccag agtgcggcga tccagcagat acagaaggtt caggttgata caaataataa
    18061 cctgaacagc atgtgggctg tgaagctgca gcagatgcag gacggacgcc tttatatcgc
    18121 gggtattggt gccggtattg agaacacccc tgacggcatg cagagtcagg tgctgctggc
    18181 ggcggacagg attgcgatgg ttaatcctgc gaatggcaac acaaagccga tgtttgttgg
    18241 tcagggcgat cagatattca tgaacgaagt gttcctgaaa tatctgacgg ctcccaccat
    18301 taccagcggc ggtaatcctc cggcattttc cctgacaccg gacgggcggc tgacggcgaa
    18361 aaatgccgat atcagcggta acgtgaatgc gaactccggg acgctcaaca acgtcacgat
    18421 taacgagaac tgccgggttc tgggaaaact gtccgcgaac cagattgaag gcgatctcgt
    18481 taaaacggtg ggcaaagctt tcccccggga ctcccgtgca ccggagcggt ggccatcagg
    18541 aaccattacc gtcagggttt atgacgatca gccgtttgac cggcaaattg ttatcccggc
    18601 ggtggcattc agtggcgcta aacatgagca agatcatact gatatctact cctcatgccg
    18661 tctgatagta cgaaaaaacg gtgctgaaat ttataaccga acggctctgg ataatacgct
    18721 gatatatacg ggtgttattg atatgcctgc aggcagtggt gtcatgacac tggaattttc
    18781 tgtatcggca tggctggtaa atg
//
LOCUS       DADXDL010000099        17229 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.099, whole genome shotgun sequence.
ACCESSION   DADXDL010000099 DADXDL010000000
VERSION     DADXDL010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 17229)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17229)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17229
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.099"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            38..1177
                     /gene="arnB"
                     /locus_tag="IRB70_003937"
     CDS             38..1177
                     /gene="arnB"
                     /locus_tag="IRB70_003937"
                     /EC_number="2.6.1.87"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_024188371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-4-amino-4-deoxy-L-arabinose
                     aminotransferase"
                     /protein_id="HBC0633790.1"
                     /translation="MSEFLPFSRPAMGVEELAAVKEVLESGWITTGPKNQALEQAFCQ
                     LTGNQHAIAVSSATAGMHITLMALEIGKGDEVITPSLTWVSTLNMISLLGATPVMVDV
                     DRDTLMVTPEAIESAITPRTKAIIPVHYAGAPADIDAIRAIGERYGIAVIEDAAHAVG
                     TYYKGRHIGAKGTAIFSFHAIKNITCAEGGLIVTDNENLARQLRMLKFHGLGVDAYDR
                     QTWGRAPQAEVLTPGYKYNLTDINAAIALTQLAKLEHLNTRRREIVQQYQQALAALPF
                     QPLSLPAWPHVHAWHLFIIRVDEQRCGISRDALMEALKERGIGTGLHFRAAHTQKYYR
                     ERFPTLSLPNTEWNSERICSLPLFPDMTTADADRVITALQQLAGQ"
     gene            1181..2149
                     /gene="arnC"
                     /locus_tag="IRB70_003938"
     CDS             1181..2149
                     /gene="arnC"
                     /locus_tag="IRB70_003938"
                     /EC_number="2.4.2.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate
                     4-deoxy-4-formamido-L-arabinose transferase"
                     /protein_id="HBC0633791.1"
                     /translation="MFEIHPVKKVSVVIPVYNEQESLPELIRRTTKACESLGKEYEIL
                     LIDDGSSDNSAHMLVEASQAEGSHIVSILLNRNYGQHSAIMAGFSHVTGDLIITLDAD
                     LQNPPEEIPRLVAKADEGYDVVGTVRQNRQDSWFRKTASKMINRLIQRTTGKAMGDYG
                     CMLRAYRRHIVDAMLHCHERSTFIPILANIFARRAIEIPVHHAEREFGESKYSFMRLI
                     NLMYDLVTCLTTTPLRMLSLLGSIIAIGGFSIAVLLVILRLTFGPQWAAEGVFMLFAV
                     LFTFIGAQFIGMGLLGEYIGRIYTDVRARPRYFVQQVIRPSSKENE"
     gene            2149..4131
                     /gene="arnA"
                     /locus_tag="IRB70_003939"
     CDS             2149..4131
                     /gene="arnA"
                     /locus_tag="IRB70_003939"
                     /EC_number="1.1.1.305"
                     /EC_number="2.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-4-amino-4-deoxy-L-arabinose
                     formyltransferase/UDP-glucuronic acid oxidase ArnA"
                     /protein_id="HBC0633792.1"
                     /translation="MKTVVFAYHDMGCLGIEALLAAGYEISAIFTHTDNPGEKAFYGS
                     VARLAAERGIPVYAPDDVNHPLWVERIAQLSPDVIFSFYYRHLIHDKILQLAPAGAFN
                     LHGSLLPKYRGRAPLNWVLVNGETETGVTLHRMVKRADAGAIVAQLRIAIAPDDIAIT
                     LHHKLCHAARQLLEQTLPAIKDGNILEIAQCENEATCFGRRTPEDSFLEWHKSAAVLH
                     NMVRAVADPWPGAFSYVGNQKFTVWSSRVHPHTSAAQPGSVISVAPLLIACGDGALEI
                     VTGQAGDGITMQGSQLAQTLGLVQGSRLNSQPVCAARRRTRVLILGVNGFIGNHLTER
                     LLREDHYEVYGLDIGSDAISRFLNHPHFHFVEGDISIHSEWIEYHVKKCDVVLPLVAI
                     ATPIEYTRNPLRVFELDFEENLRIIRYCVKYRKRIIFPSTSEVYGMCSDKYFDEDHSN
                     LIVGPVNKPRWIYSVSKQLLDRVIWAYGEKEGLQFTLFRPFNWMGPRLDNLNAARIGS
                     SRAITQLILNLVEGSPIKLIDGGKQKRCFTDIRDGIEALYRIIENAGNRCDGEIINIG
                     NPDNEASIEELGQMLLASFEKHPLRHHFPPFAGFRVVESSSYYGKGYQDVEHRKPSIR
                     NARRCLDWEPKIDMQETIDETLDFFLRTVELTDKPS"
     gene            4128..5018
                     /locus_tag="IRB70_003940"
     CDS             4128..5018
                     /locus_tag="IRB70_003940"
                     /EC_number="3.5.1.n3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-deoxy-4-formamido-L-arabinose-
                     phosphoundecaprenol deformylase"
                     /protein_id="HBC0633793.1"
                     /translation="MTKVGLRIDVDTFRGTREGVPRLLEILSKHNIQASIFFSVGPDN
                     MGRHLWRLVKPQFLWKMLRSNAASLYGWDILLAGTAWPGKEIGHANADIICEAAKHHE
                     VGLHAWDHHAWQAHSGNWDRQTLVDDIARGLRTLEEIIGQPVTCSAAAGWRADQQVIE
                     AKEAFHLRYNSDCRGAMPFRPLLESGNPGTAQIPVTLPTWDEVIGRDVKAEDFNGWLL
                     NRILRDKGTPVYTIHAEVEGCAYQHNFVDLLKRAAQEGVTFCPLSELLSGMLPLGQVV
                     RGNIAGREGWLGCQQIAGSR"
     gene            5018..6670
                     /gene="arnT"
                     /locus_tag="IRB70_003941"
     CDS             5018..6670
                     /gene="arnT"
                     /locus_tag="IRB70_003941"
                     /EC_number="2.4.2.43"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipid IV(A)
                     4-amino-4-deoxy-L-arabinosyltransferase"
                     /protein_id="HBC0633794.1"
                     /translation="MKSVRYLIGLFAFIACYYLLPISTRLLWQPDETRYAEISREMLA
                     SGDWIVPHLLGLRYFEKPIAGYWINSIGQWLFGANNFGVRAGVIFATLLTAALVTWFT
                     LRLWRDKRLALLAAVIYLSLFIVYAIGTYAVLDPFIAFWLVAGMCSFWLAMQAQTWKG
                     KSAGFLLLGITCGMGVMTKGFLALAVPVLSVLPWVATQKRWKDLFIYGWLAVISCVLT
                     VLPWGLAIAQREPDFWHYFFWVEHIQRFAMDDAQHRAPFWYYLPVIIAGSLPWLGLLP
                     GALYAGWKNRKHSATVYLLSWTIMPLLFFSVAKGKLPTYILSCFAPLAMLMAHYALLA
                     AKNNPLALRINGWINIAFGVTGIIATFVVSPWGPMNTPVWQTFESYKVFCAWSIFSLW
                     AFFGWYTLTNVEKTWSFAALCPLGLALLVGFSIPDRVMEGKHPQFFVEMTQESLQPSR
                     YILTDSVGVAAGLAWSLQRDDIIMYRQTGELKYGLNYPDAKGRFVSGDEFANWLNQHR
                     QEGIITLVLSVDRDEDINSLAIPPADAIDRQERLVLIQYRPK"
     gene            6667..7002
                     /gene="arnE"
                     /locus_tag="IRB70_003942"
     CDS             6667..7002
                     /gene="arnE"
                     /locus_tag="IRB70_003942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnE"
                     /protein_id="HBC0633795.1"
                     /translation="MIWLTLVFASLLSVAGQLCQKQATCFVAINKRRKHIVLWLGLAL
                     ACLGLAMVLWLLVLQNVPVGIAYPMLSLNFVWVTLAAVKLWHEPVSPRHWCGVAFIIG
                     GIVILGSTV"
     gene            7002..7388
                     /gene="arnF"
                     /locus_tag="IRB70_003943"
     CDS             7002..7388
                     /gene="arnF"
                     /locus_tag="IRB70_003943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311173.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-amino-4-deoxy-L-arabinose-phosphoundecaprenol
                     flippase subunit ArnF"
                     /protein_id="HBC0633796.1"
                     /translation="MGLVWGLFSVIIASVAQLSLGFAASHLPPMTHLWDFIAALLAFG
                     LEARILLLGLLGYLLSVFCWYKTLHKLALSKAYALLSMSYVLVWIASMVLPGWEGTFS
                     LKALLGVACIMSGLMLIFLPTTKQRY"
     gene            complement(7382..7648)
                     /gene="pmrD"
                     /locus_tag="IRB70_003944"
     CDS             complement(7382..7648)
                     /gene="pmrD"
                     /locus_tag="IRB70_003944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416762.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction protein PmrD"
                     /protein_id="HBC0633797.1"
                     /translation="MEWLVKKSCCDKQDNRHVLKLCDAGGTIKMIAEVKSDFAVKVGD
                     LLSPLQNALYCINREKLHTVKVLSASSYSPDEWERQCQSAGKTQ"
     gene            complement(7758..9113)
                     /gene="menE"
                     /locus_tag="IRB70_003945"
     CDS             complement(7758..9113)
                     /gene="menE"
                     /locus_tag="IRB70_003945"
                     /EC_number="6.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000577608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate--CoA ligase"
                     /protein_id="HBC0633798.1"
                     /translation="MIFSDWPWRHWRQVRGEAIALRLNDEQLNWRELCARVDELASGF
                     VAQGVVEGSGVMLRAWNTPQTLLAWLALLQCGARVLPVNPQLPQPLLEELLPNLTLQF
                     ALVPDGENTFPALTSLHIQLVEGAHAAAWQPTRLCSMTLTSGSTGLPKAAVHTYQAHL
                     ASAQGVLSLIPFGEHDDWLLSLPLFHVSGQGIMWRWLYAGARMTVRDKQPLEQMLAGC
                     THASLVPTQLWRLLVNRSSVSLKAVLLGGAAIPVELTEQAREQGIRCFCGYGLTEFAS
                     TVCAKEADGLADVGSPLPGREVKIVNDEVWLRAASMAEGYWRNGQRVPLVNDEGWYAT
                     RDRGEMHNGKLTIVGRLDNLFFSGGEGIQPEEVERVIAAHPAVLQVFIVPVADKEFGH
                     RPVAVVEYDQQTVDLDEWVKDKLARFQQPVRWLTLPSELKNGGIKISRRALKEWVQRQ
                     D"
     gene            complement(9110..10072)
                     /gene="menC"
                     /locus_tag="IRB70_003946"
     CDS             complement(9110..10072)
                     /gene="menC"
                     /locus_tag="IRB70_003946"
                     /EC_number="4.2.1.113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="o-succinylbenzoate synthase"
                     /protein_id="HBC0633799.1"
                     /translation="MRSAQVYRWQIPMDAGVVLRDRRLKTRDGLYVCLREGEREGWGE
                     ISPLPGFSQETWEEAQSVLLAWVNNWLAGDCELPQMPSVAFGVSCALAELADTLPQAA
                     NYRAAPLCNGDPDDLILKLADMPGEKVAKVKVGLYEAVRDGMVVNLLLEAVPDLHLRL
                     DANRAWTPLKGQQFAKYVNPDYRHRIAFLEEPCKTRDDSRAFTRETGIAIAWDESLRE
                     PDFAFVAEQGVRAVVIKPTLTGSLEKVREQVQAAHALGLTAVISSSIESSLGLTQLAR
                     IAAWLTPDTIPGLDTLDLMQAQQVRRWPGSPLPLVEVDALERLL"
     gene            complement(10072..10929)
                     /gene="menB"
                     /locus_tag="IRB70_003947"
     CDS             complement(10072..10929)
                     /gene="menB"
                     /locus_tag="IRB70_003947"
                     /EC_number="4.1.3.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001641973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoyl-CoA synthase"
                     /protein_id="HBC0633800.1"
                     /translation="MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSADGIAKITINRPQV
                     RNAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDDSG
                     VHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNAIFGQTGPKVG
                     SFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVPLADLEKETVRWC
                     REMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEGQEGRNAFNQKRQP
                     DFSKFKRNP"
     gene            complement(10944..11702)
                     /gene="menH"
                     /locus_tag="IRB70_003948"
     CDS             complement(10944..11702)
                     /gene="menH"
                     /locus_tag="IRB70_003948"
                     /EC_number="4.2.99.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-6-hydroxy-2,
                     4-cyclohexadiene-1-carboxylate synthase"
                     /protein_id="HBC0633801.1"
                     /translation="MILHAQAKHGKPGLPWLVFLHGFSGDCHEWQEVGEVFADYSRLY
                     VDLPGHGGSAAISVDGFDDVTGLLCKTLVSYNILDFWLVGYSLGGRVAMMAACQGLAG
                     LCGVVVEGGHPGLQNAEQRTQRQRSDRQWAQRFRTEPLTAVFADWYQQPVFASLNDEQ
                     RRELVALRSNNNGATLAAMLEATSLAVQPDLRANLSARTFAFYYLCGERDSKFRALAA
                     ELAAECHVIPRAGHNAHRENPAGVIASLAQILRF"
     gene            complement(11699..13369)
                     /gene="menD"
                     /locus_tag="IRB70_003949"
     CDS             complement(11699..13369)
                     /gene="menD"
                     /locus_tag="IRB70_003949"
                     /EC_number="2.2.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-succinyl-5-enolpyruvyl-6-hydroxy-3-
                     cyclohexene-1-carboxylic-acid synthase"
                     /protein_id="HBC0633802.1"
                     /translation="MSVSAFNRRWAAVILEALTRHGVRHICIAPGSRSTPLTLAAAEN
                     SAFIHHTHFDERGLGHLALGLAKVSKQPVAVIVTSGTAVANLYPALIEAGLTGEKLIL
                     LTADRPPELIDCGANQAIRQPGMFASHPTHSISLPRPTQDIPARWLVSTIDHALGTLH
                     AGGVHINCPFAEPLYGEMDDTGLSWQQRLGDWWQDDKPWLREAPRLESEKQRDWFFWR
                     QKRGVVVAGRMSAEEGKKVALWAQTLGWPLIGDVLSQTGQPLPCADLWLGNAKATSEL
                     QQAQIVVQLGSSLTGKRLLQWQASCEPEEYWIVDDIEGRLDPAHHRGRRLIANIADWL
                     EQHPAEKRQPWCVEIPRLAEQAMQAVIARRDAFGEAQLAHRISDYLPEQGQLFVGNSL
                     VVRLIDALSQLPAGYPVYSNRGASGIDGLLSTAAGVQRASGKPTLAIVGDLSALYDLN
                     ALALLRQVSAPLVLIVVNNNGGQIFSLLPTPKNERERFYLMPQNVHFEHAAAMFELKY
                     HRPQNWQELETALADAWRTPTTTVIEMVVNDTDGAQTLQQLLAQVSHL"
     gene            complement(13458..14753)
                     /gene="menF"
                     /locus_tag="IRB70_003950"
     CDS             complement(13458..14753)
                     /gene="menF"
                     /locus_tag="IRB70_003950"
                     /EC_number="5.4.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311180.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isochorismate synthase MenF"
                     /protein_id="HBC0633803.1"
                     /translation="MQSLTTALENLLRHLSQEIPATPGIRVIDIPFPLKDAFDALSWL
                     ASQQVYPQFYWQQRNGDEEAAVLGAITRFTSLDQAQRFLRQHPEHADLRIWGLNAFDP
                     SQGNLLLPRLEWRRCGGKATLRLTLFSERSLQHDAIKAKEFIATLVSIKPLPGLHLTT
                     TREQHWPDKTGWTQLIELATKTIAEGELDKVVLARATDLHFASPVNAAAMMAASRRLN
                     LNCYHFYMAFDGENAFLGSSPERLWRRRDKALRTEALAGTVANHPDDKQAQRLGEWLM
                     ADDKNQRENMLVVEDICQRLQADTQTLDVLPPQVLRLRKVQHLRRCIWTALNKADDVI
                     CLHQLQPTAAVAGLPRDLARQFIARHEPFTREWYAGSAGYLSLQQSEFCVSLRSAKIS
                     GNVVRLYAGAGIVRGSDPEQEWQEIDNKAAGLRTLLQME"
     gene            complement(14832..15137)
                     /gene="elaB"
                     /locus_tag="IRB70_003951"
     CDS             complement(14832..15137)
                     /gene="elaB"
                     /locus_tag="IRB70_003951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response protein ElaB"
                     /protein_id="HBC0633804.1"
                     /translation="MSNQFGDTRIDDDLTLLSETLEEVLRSSGDPADQKYVELKARAE
                     KALDDVKKRVSQASDSYYYRAKQAVYRADDYVHEKPWQGIGVGAAVGLVLGLLLARR"
     gene            complement(15192..15653)
                     /locus_tag="IRB70_003952"
     CDS             complement(15192..15653)
                     /locus_tag="IRB70_003952"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416770.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBC0633805.1"
                     /translation="MIEWQDLHHSELSVSQLYALLQLRCAVFVVEQNCPYQDIDGDDL
                     TRDNRHILGWKNDELVAYARILKSDDDLEPVVIGRVIVSEALRGEKVGQQLMSKTLET
                     CTRHWPDKPVYLGAQAHLQNFYQSFGFIPVTEVYEEDGIPHIGMAREVIQA"
     gene            15718..16635
                     /gene="rbn"
                     /locus_tag="IRB70_003953"
     CDS             15718..16635
                     /gene="rbn"
                     /locus_tag="IRB70_003953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416771.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease BN"
                     /protein_id="HBC0633806.1"
                     /translation="MELIFLGTSAGVPTRTRNVTAILLNLQHPTQSGLWLFDCGEGTQ
                     HQLLHTAFNPGKLDKIFISHLHGDHLFGLPGLLCSRSMSGIVQPLTIYGPQGIREFVE
                     TALRISGSWTDYPLEIVEIGAGEIFDDGLRKVTAYPLEHPLECYGYRIEEHDKPGALN
                     AQALKAAGVPPGPLFQELKAGKTIMLEDGRQINGADYLAAPVPGKALAIFGDTGPCDA
                     ALDLAKGVDVMVHEATLDITMEAKANSRGHSSTRQAATLAREAGVGKLIITHVSSRYD
                     DKGCQHLLRECRSIFPATELANDFTVFNV"
     gene            16826..>17229
                     /locus_tag="IRB70_003954"
     CDS             16826..>17229
                     /locus_tag="IRB70_003954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311184.2"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deubiquitinase"
                     /protein_id="HBC0633807.1"
                     /translation="MVTVVSNYCQLSQTQLSQTFAEKFTVTDELLQSLKKTALSGDEE
                     SIELLHNIALGYDEFGKKAEDILYHIVINPTNETLSIIRLIKNACLKLYNLAHTATKH
                     PLKSHDSDDLLFKKLFSPSKLMTIIGEDIPLIS"
BASE COUNT         4038 a         4654 c         4360 g         4177 t
ORIGIN      
        1 ataagtggac aggtattcaa tggcggaagg aaaagcaatg tcagaatttt tgcctttttc
       61 gcgaccagca atgggcgtgg aggaactcgc tgcagttaaa gaggttctcg aatccggttg
      121 gatcacaacc ggtccgaaga atcaggcgct tgaacaagcc ttttgccagt tgacgggaaa
      181 tcagcatgcc atcgcggtca gttcagccac cgccggaatg catatcacgc taatggcgtt
      241 ggaaattggc aagggcgatg aagtgattac gccttccctg acctgggttt caaccctcaa
      301 tatgatctcc ttgttgggtg caacgccggt aatggtggat gtcgaccgcg atacgctgat
      361 ggtcacgcct gaagcgatcg agtcagccat tacgccacgc actaaagcca tcattccggt
      421 gcattatgcc ggtgcgccag cagatattga cgccattcgc gccattggcg aacgttacgg
      481 catcgcagtt atcgaagatg ctgcccatgc cgtcggtacg tattacaaag ggcgacatat
      541 tggcgcaaaa ggtaccgcta ttttttcatt tcatgccatt aaaaatatta cctgtgctga
      601 aggtggcctg attgtaactg ataatgaaaa ccttgcccgc cagctacgga tgctgaaatt
      661 tcacggtctg ggtgtcgatg cctatgacag acaaacctgg ggccgtgcac cgcaagctga
      721 agtcttaaca ccgggctata agtacaatct gaccgatatt aacgccgcga ttgccctgac
      781 acagttagca aaattagagc acctcaacac ccgtcggcgc gaaattgtcc agcaatatca
      841 gcaagcactg gcagctctcc cctttcagcc attaagcctt cccgcctggc cgcacgttca
      901 cgcctggcat ctgtttatta ttcgtgtcga tgaacaacgt tgtggtatca gtcgcgatgc
      961 gttgatggaa gcgttaaaag aaagaggtat tggtaccggg ttacatttcc gcgccgctca
     1021 cacacaaaaa tattatcgcg agcgttttcc cacgctgtcg ttaccgaata ccgaatggaa
     1081 tagcgaacgc atctgttcgt tgccgctgtt cccggatatg accaccgccg atgccgaccg
     1141 cgtcatcaca gcccttcagc aactcgcagg acaataagcc atgtttgaaa tccaccctgt
     1201 taagaaagtc tcggtggtta ttcccgttta taacgagcag gaaagcttac cggaattaat
     1261 caggcgcacc acaaaagcct gtgaatcact ggggaaagag tatgagatcc tgctgattga
     1321 tgacggcagt agcgataatt ccgcgcatat gctggtcgaa gcctcacaag cggagggcag
     1381 ccatattgtg tctattttgc ttaaccgcaa ttacgggcaa cattcagcga ttatggcggg
     1441 attcagtcac gtcaccggcg acttaattat taccctcgat gccgatctcc agaatccgcc
     1501 agaggaaatc ccccgtctgg tggcaaaagc cgatgaaggt tacgacgtgg tagggactgt
     1561 acgccagaac cgccaggaca gctggtttcg taaaaccgct tcgaagatga ttaaccggct
     1621 tattcagcgc accactggca aagcgatggg tgactatggt tgtatgctgc gcgcctatcg
     1681 ccgtcatatt gtcgatgcga tgttgcactg ccatgaacgc agcaccttta tcccgattct
     1741 ggcgaatatc ttcgcccgcc gtgccattga aattccagtg catcatgccg agcgtgagtt
     1801 tggtgaatcc aaatacagct ttatgcgcct gattaatttg atgtacgacc tggtgacctg
     1861 ccttaccact acgccgctac gtatgctgag tctgctcggc agcattattg cgattggcgg
     1921 ttttagcatt gcggtgctgt tggtgatttt acgcctgacc ttcggacccc aatgggcggc
     1981 agaaggcgtc tttatgctat ttgccgtgct gtttactttt attggcgctc agtttatcgg
     2041 catgggattg ctcggtgaat atatcggcag gatctacacc gatgtccgcg cccgcccccg
     2101 ctattttgtt cagcaagtta tccgtccatc cagcaaggaa aatgaataat gaaaaccgtc
     2161 gtttttgcct accacgatat gggatgcctc ggtattgaag ccctgctggc tgccggttac
     2221 gaaattagcg ccatttttac ccatactgat aatcccggtg aaaaagcctt ttatggttcg
     2281 gtggctcgtc tggcagcgga aagaggcatt ccggtttatg cgccggatga cgttaaccat
     2341 ccgctgtggg tggaacgcat tgcccaacta tcaccagatg tgattttctc tttttattat
     2401 cgccatctta ttcacgacaa gattttgcag ctcgctcctg caggcgcatt taatctgcat
     2461 ggttcactgt taccaaaata tcgtggtcgc gcgccgctga actgggtgct ggtgaacggt
     2521 gaaacggaaa ctggcgtgac attgcaccga atggtgaaac gtgccgatgc tggggccatt
     2581 gtagcccaac tgcgcattgc cattgcgcca gacgatatcg ccattacgct gcatcataag
     2641 ttatgccatg ccgcgcgaca gctactggag cagacattac ccgccattaa agacggtaat
     2701 attctggaaa tcgcccagtg cgaaaacgaa gccacctgtt ttggtcgcag aacgccagaa
     2761 gacagcttcc tcgagtggca caaatcggca gcagtattgc ataacatggt gcgtgcagtc
     2821 gccgatccgt ggccgggtgc cttcagctat gttggtaatc aaaaatttac cgtctggtcg
     2881 tcacgcgtac atcctcatac atccgcagcg cagccgggaa gcgtgatttc tgttgcgccg
     2941 ttgctgattg cctgtggcga tggcgcgctg gaaatcgtca ccggacaggc gggcgacggc
     3001 attactatgc agggctcaca attagcccag acgctggggc tggtgcaagg ttcacgcttg
     3061 aatagccagc cggtctgcgc cgcccgacgc cgtacccggg tactcatcct cggtgtgaat
     3121 ggctttattg gcaaccatct gacagaacgc ctgctgcgcg aagatcatta tgaagtttac
     3181 ggtctggata ttggcagcga tgcgataagc cgttttctga atcatccgca ttttcacttt
     3241 gtcgaaggcg atatcagtat tcattccgaa tggattgagt atcacgtcaa aaaatgtgat
     3301 gtcgtcttgc ctttggtggc gatagccacg ccgattgaat atacccgcaa cccgctgcgc
     3361 gtatttgaac tcgatttcga agagaatctg cgcattatcc gctactgcgt gaagtaccgt
     3421 aagcgaatca tcttcccgtc gacttcagaa gtttatggga tgtgtagcga taaatacttc
     3481 gatgaggacc attctaattt aatcgtcggc ccggtgaata aaccacgctg gatttattcg
     3541 gtgtctaaac aattacttga tcgagtgatc tgggcctatg gcgaaaaaga ggggttacag
     3601 ttcaccctct tccgcccgtt taactggatg ggaccgcgac tggataacct taatgcagcg
     3661 cgaatcggca gctcccgcgc gattacgcaa ctcattctca atctggtaga aggttcacca
     3721 attaagctga ttgatggcgg aaaacaaaaa cgctgcttta ctgatattcg cgatggtatc
     3781 gaggcgttat accgcattat cgaaaatgcg ggaaatcgct gcgacggcga aattatcaac
     3841 attggcaatc ctgataacga agcgagcatt gaggaactgg gccagatgct gctggcgagc
     3901 ttcgaaaaac atccgctgcg ccatcacttc ccaccgtttg cgggctttcg tgttgtcgaa
     3961 agtagcagct actacggcaa aggatatcag gacgtagagc atcgtaaacc aagcatccgc
     4021 aatgcccgcc gctgcctgga ctgggagccg aaaattgata tgcaggaaac catcgacgaa
     4081 acgctggatt tcttcctgcg caccgtcgag cttacggata aaccatcatg acaaaagtag
     4141 gcttacgcat tgatgtcgat acctttcgtg gcacccgtga aggcgtgccg cgtctgctgg
     4201 aaatcttgag taagcataat attcaggcca gcattttttt cagcgtcggc ccggacaata
     4261 tgggccgcca tctctggcga ctggtgaagc cacagttttt gtggaagatg ctgcgctcaa
     4321 acgcggcatc gctttatggc tgggatattt tactggcagg tacggcctgg ccaggtaaag
     4381 agattggtca tgccaatgcc gatatcattt gtgaagcagc taaacatcac gaagtcggcc
     4441 tgcacgcctg ggatcaccat gcctggcaag cccatagcgg taactgggat cggcaaacat
     4501 tggtcgacga tattgcacgc ggccttcgca ctctggaaga gattatcggt caaccggtaa
     4561 cctgttctgc cgctgcgggc tggcgtgccg accagcaggt gatcgaagca aaagaagcgt
     4621 tccatttgcg ctacaacagc gattgtcgtg gggccatgcc gtttcggcca ctgctcgaat
     4681 caggaaaccc tggcactgcg caaattccgg tgaccttacc cacctgggat gaagtgattg
     4741 gtcgggatgt gaaagcagaa gattttaacg gttggttact caaccgcatc ctgcgagata
     4801 aaggcacgcc ggtttatacc attcatgccg aagttgaagg ctgcgcttat cagcataatt
     4861 ttgtggatct cctcaaacgc gcagctcagg aaggcgtgac attttgccct ttaagcgaac
     4921 tgttatcagg gatgttgccg ctcggacaag ttgttcgcgg aaatattgcc ggacgtgaag
     4981 gctggctggg ttgccaacaa attgcgggta gtcgctgatg aaatcggtac gttaccttat
     5041 cggcctcttc gcgtttattg cctgctatta cctgttaccg atcagcacgc gtctgctatg
     5101 gcaacccgat gaaacgcgtt atgcggaaat cagtcgagaa atgctggcat ccggcgactg
     5161 gattgtgccc catttgttag ggctacgtta tttcgaaaaa cccattgccg gatactggat
     5221 taacagcatt gggcaatggc tatttggcgc gaataacttt ggtgtgcggg caggcgttat
     5281 ctttgcgacc ctgttaactg ccgcgctggt gacctggttt actctgcgct tatggcgcga
     5341 taaacgtctg gctctactcg ccgcagtgat ttatctctca ttgtttattg tctatgccat
     5401 tggcacttat gccgtgctcg atccgtttat tgccttctgg ctggtggcgg gaatgtgcag
     5461 cttctggctg gcaatgcagg cacagacgtg gaaaggcaaa agcgcgggat ttttactgct
     5521 gggaatcacc tgcggcatgg gggtgatgac caaaggtttt ctcgcccttg ccgtgccggt
     5581 attaagcgtg cttccatggg ttgcaacgca aaaacgctgg aaagatctct ttatttacgg
     5641 ctggctggcg gttatcagtt gcgtactgac ggttctcccc tggggactgg cgatagcgca
     5701 gcgggagcct gacttctggc actatttttt ctgggttgag catattcaac gctttgcaat
     5761 ggatgatgct cagcatagag ctccgttctg gtactacttg ccggtcatca ttgccggtag
     5821 cctgccgtgg ctgggattac tccccggagc actgtacgca ggctggaaaa accgcaagca
     5881 ttccgcaacc gtctatttgt tgagctggac gataatgccg ctgctgtttt tctccgtcgc
     5941 taaaggcaaa ttgcccacct atattctttc ctgctttgca cctctggcaa tgctgatggc
     6001 gcattacgct ttgctggcag caaaaaataa tcctctggcg ctgcggatta atggctggat
     6061 taacatcgct tttggtgtca ctggcattat tgccacattt gtggtctccc catggggacc
     6121 aatgaacacg ccagtgtggc aaaccttcga gagctataaa gtcttttgtg cctggtcgat
     6181 tttttcgcta tgggcatttt tcggctggta caccttaaca aacgtcgaaa agacctggtc
     6241 ttttgccgcg ctttgcccgc tggggctggc gttgctggta ggattttcaa ttcctgacag
     6301 agtcatggaa ggaaaacatc cgcaattttt tgtcgagatg acacaagaat cacttcagcc
     6361 aagccgctat attcttactg atagcgtcgg tgttgccgca ggtctggcat ggagcctgca
     6421 acgcgatgac atcatcatgt atcgccagac aggtgagttg aaatacggcc ttaattatcc
     6481 ggatgcgaaa gggagatttg tcagcggtga tgagttcgca aactggctta atcaacatcg
     6541 tcaggagggg attattacac tcgtactttc ggttgaccgc gatgaagata tcaacagtct
     6601 cgccattccg cccgcagatg ccatcgatcg tcaggagcgt ctggtgctga ttcagtatcg
     6661 tcccaaatga tctggctaac attagtcttt gccagcttgc ttagcgttgc cgggcagttg
     6721 tgtcagaaac aggcaacctg ctttgtggcg ataaacaaac ggcgcaaaca tatcgtgctg
     6781 tggctgggac tggcgctggc ttgtcttggt cttgccatgg tgctctggct gctggtcttg
     6841 cagaacgtac cggtaggcat tgcctacccg atgttaagtc tgaattttgt ctgggtgacg
     6901 ctggctgcag taaaactgtg gcacgaaccg gtatcgccgc gtcactggtg tggagtagcg
     6961 ttcattattg gcggcattgt gatcctcggg agtacggtgt aatgggtctg gtgtggggat
     7021 tattcagcgt cattattgcc tcagttgcgc aattaagcct cggttttgcg gcgagtcatc
     7081 tgccgccgat gacgcactta tgggatttta tcgcggcgct gttagctttt ggcctggagg
     7141 cacggatact gttgcttggg ctgctgggtt atctgctttc cgttttttgt tggtataaaa
     7201 cactacataa acttgcacta agcaaagcct atgccttgct cagtatgagt tatgtgctgg
     7261 tatggattgc ttcaatggta cttcccggct gggaaggaac tttttcgctg aaagcactac
     7321 tgggagtagc ctgtattatg agcgggttga tgctgatttt cctgcccacc acaaaacaac
     7381 gttactgagt tttcccagcc gattgacact gccgttccca ctcatcgggg ctgtagctgc
     7441 ttgccgagag gactttcacc gtatgcagct tttcacgatt aatacaataa agcgcattct
     7501 gcaaaggcga gagtaaatcc cccactttca cggcgaagtc actcttcact tcggcaatca
     7561 tttttatcgt gccaccagca tcacaaagct taagtacatg tctgttatct tgtttatcac
     7621 agcatgactt tttaaccagc cattccattg caccaccctg tttgataaga attttcacat
     7681 taatttacag attaacagat aaacctatta tcaacggcaa tggaatggca aaattgcgaa
     7741 gtgaaactaa tgatttctta atcctggcgt tgcacccact cttttagcgc ccgacgtgaa
     7801 attttaatac cgccgttttt cagttctgat ggtaacgtta accaacgcac cggttgctga
     7861 aaacgagcca acttgtcttt cacccattcg tcaagatcaa cggtttgctg gtcatactcc
     7921 accaccgcta ctggccgatg accaaactcc ttgtcggcaa cggggacgat aaacacctgc
     7981 aaaaccgcag gatgtgcagc aataacgcgc tcgacttctt ccggctgaat accctcaccg
     8041 ccactgaaga atagattgtc taaacgtccg acaatggtca gcttgccatt atgcatctca
     8101 ccgcgatcgc gcgtggcgta ccagccttcg tcattaacca gtggaacccg ttgcccgtta
     8161 cgccagtaac cttctgccat actggcagcc cgcagccaca cttcatcatt aacgattttc
     8221 acttcccgac ccggcagcgg cgaaccaacg tccgccaggc cgtcggcttc tttcgcacac
     8281 accgtggagg caaactcggt cagaccatag ccgcaaaagc aacgaatccc ctgctcgcgc
     8341 gcctgttccg tcaactcgac cgggatagcc gcgccgccaa gtaaaaccgc tttcagggaa
     8401 acggaactac ggttaaccag caaacgccag agttgtgttg gcaccagtga agcgtgagta
     8461 cagcctgcca gcatttgctc caggggctgt ttatcacgta ccgtcatccg cgcaccagcg
     8521 tataaccagc gccacataat cccctgaccg gagacgtgaa acagcggtaa agagagcaac
     8581 cagtcatcgt gctcgccaaa cggtatcagc gataacacac cttgcgcact ggcaagatgg
     8641 gcctgataag tatgaacagc ggctttcggc aaaccggtag agccggaggt caacgtcatt
     8701 gagcacagac gcgtcggctg ccacgcagcg gcatgtgcgc cttcaaccag ctgaatgtgc
     8761 agcgacgtta acgccggaaa cgtgttttcc ccatccggca ccagcgcaaa ttgcagcgtc
     8821 agattgggca gcaattcctc aagcaacggt tgcggcagtt gagggttcac gggcagcacc
     8881 cgcgccccgc attgcagtaa cgccagccag gcgagcagcg tttgcggcgt attccacgcc
     8941 cgcaacatca cgccgctgcc ctcaacaacg ccctgtgcca caaagccgga ggctaattca
     9001 tcgacgcgag cacaaagctc gcgccagtta agttgctcgt cattaagacg taaggcgatg
     9061 gcttctcccc gcacttgccg ccagtgacgc cacggccagt cagagaagat cataacagcc
     9121 gctccagtgc atcaacttcc actaacggta gcgggctacc cggccagcga cgaacctgct
     9181 gcgcctgcat cagatccagc gtgtccagtc ccggaatggt gtctggcgtt aaccaggcag
     9241 caatccgcgc cagttgcgtt agacctaagc tcgactcaat ggaagaactg atcaccgccg
     9301 tcagccccag cgcgtgcgcc gcctgcacct gctcacgtac tttctccagg ctacccgtga
     9361 gcgtgggttt gataactacc gcgcgcacgc cctgttcagc gacaaaggca aaatccggct
     9421 cgcgcaggct ttcatcccaa gcaatggcaa tgccggtttc acgggtaaac gctcgcgaat
     9481 catcgcgggt tttacacggc tcttcgagaa aagcaatgcg gtggcgataa tccgggttaa
     9541 cgtatttggc aaactgctgg cctttcagcg gcgtccaggc gcgattcgcg tcaagacgca
     9601 aatgcagatc aggaaccgcc tccagcaaca gattgaccac catgccgtcg cgcacggctt
     9661 cgtacaatcc cactttgacc ttcgccactt tctcgcccgg catatcggca agtttgagga
     9721 tcagatcgtc aggatcgcca ttacacagtg gtgccgcacg gtaattggcc gcctgcggga
     9781 gcgtatctgc cagctccgcc aatgcacagc ttacgccaaa ggccacggaa ggcatctgcg
     9841 gtaattcgca atcgcctgcc agccagttat ttacccaggc aagcagcacg ctttgcgcct
     9901 cttcccaggt ttcctggctg aagcccggca gtggggagat ctccccccac ccttcgcgct
     9961 cgccctcacg caggcaaacg tacagcccgt cgcgggtttt taaccgcctg tcgcgcagaa
    10021 ccacccccgc gtccatgggg atctgccagc ggtatacctg cgcgctacgc attacggatt
    10081 ccgtttaaat ttgctgaagt caggctgacg tttctggttg aaggcgttgc gaccttcctg
    10141 accttcttcc gtcatgtaga acagcatggt ggcgttgccc gccagctcct gcagacctgc
    10201 ctgaccgtca cagtcggcgt tcagtgcagc tttcaggcag cgcagcgcca tcgggctgtt
    10261 ttgcagcatt tcacggcacc agcgcacggt ttctttttcc agatccgcca gcggtaccac
    10321 ggtgtttaca aggcccatat ccagcgcctg ttttgcgtcg tactgacggc acaggaacca
    10381 gatttcacgc gcttttttct gtccaacaat gcgcgccatg taggaagcgc cccagccgcc
    10441 gtcgaaggaa ccgactttcg ggccagtctg accgaagatg gcattatctg ccgcgatagt
    10501 caggtcgcac atcatgtgca gaacgtgacc gccgccgatg gagtagccag ccaccatcgc
    10561 gacaactggt ttcggacagg tacgaatctg acgctggaag tccagcacgt tcaggtgatg
    10621 tacgccggaa tcatctttat agccgccgta atcaccacgc actttctggt caccaccgga
    10681 gcagaacgct ttatcgcctg cgccagtcag aatgatcacg ccgatgttgt cgtcataacg
    10741 cgcatctgcc agtgcctgga tcatctcttt taccgtcaga ggacggaagg cattgcgcac
    10801 ctgcggacga ttaatggtga tttttgcgat accgtcggca gatttttcat aacgaatgtc
    10861 ctcgaaacct tcggagcagt cgtgccattc aaccggtgcg taaagcattg cttcatcagg
    10921 ataaatcata ttgtgtcctt tagtcagaaa cgcaagatct gcgccagact tgcgattacg
    10981 ccagcgggat tttcccggtg cgcgttatgt ccggcgcgag gaatgacatg gcattcggca
    11041 gccagttccg ccgccagagc gcggaatttg ctgtcacgtt caccacataa ataataaaac
    11101 gcaaatgtgc gggcgctaag gttagcacgt aaatcgggct ggacggcgag agaagtcgcc
    11161 tccagcatgg cggcaagcgt tgcgccatta ttgttgctgc gcagcgcaac cagctcccgg
    11221 cgttgttcgt cattgagtga ggcaaaaaca ggctgttgat accaatcagc aaataccgcc
    11281 gttaacggtt ctgtgcgaaa acgctgcgcc cattggcgat cggaacgctg acgttgcgtg
    11341 cgttgttcag cattttgcaa cccaggatgc ccgccttcga caacaacccc acaaagcccc
    11401 gccagcccct ggcaagccgc catcatcgcc acccgtccgc caagcgagta ccccaccagc
    11461 cagaagtcaa ggatgttgta actaaccaag gttttacaca gtaagccggt gacatcatca
    11521 aatccatcga cgctaatcgc cgccgaacca ccgtgaccag ggagatcaac atacaaccgt
    11581 gagtagtcgg caaacacctc gcccacttct tgccattcat ggcaatcgcc ggaaaaaccg
    11641 tgcaaaaaca ccagccaggg taaacctggt ttaccgtgtt ttgcctgcgc gtgcaggatc
    11701 ataaatggct tacctgcgcc agcagttgct ggagggtttg cgcaccatcg gtgtcgttaa
    11761 ccaccatttc aattaccgtg gtggtcggcg tgcgccaggc gtcggcaagt gccgtttcaa
    11821 gttcctgcca gttttgcgga cgatgatatt tcagctcgaa catcgcggcg gcgtgctcaa
    11881 aatggacgtt ttgcggcatc agatagaaac gctcgcgctc gtttttcggc gttggcaaca
    11941 gcgagaaaat ttgcccgccg ttgttgttca ccacaattaa taccagcggc gcggaaacct
    12001 gacgtaataa cgccagcgcg ttgagatcgt aaagagctga gagatcgccc acaatcgcca
    12061 gcgtcggttt gccgcttgcc cgctgaacgc ctgcggcggt cgagagcagc ccgtcgatac
    12121 cgctggcacc acggttgctg tacaccgggt aacctgccgg aagttgcgaa agcgcatcaa
    12181 tcagacgtac caccaggctg ttaccgacaa acaattgccc ctgttcaggc agatagtcgc
    12241 tgatgcgatg cgccagttgg gcttcgccaa acgcatcgcg acgggcaata accgcctgca
    12301 ttgcctgttc cgccaggcgc gggatttcaa cgcaccaggg ctggcgtttt tctgccggat
    12361 gttgctccag ccagtcggca atattggcaa ttaagcgacg tccgcgatgg tgtgccggat
    12421 caagtcgccc ttcaatgtca tcaacaatcc agtactcttc gggttcacag cttgcctgcc
    12481 attgcaggag ccgtttgccc gtcaggctgc ttcccagttg caccacaatt tgcgcctgtt
    12541 gcagttcgct ggtcgctttg gcattgccta accagagatc ggcacacggc agcggctgtc
    12601 cggtttgcga cagcacatcg ccaatcagcg gccagccaag agtttgcgcc cacagtgcga
    12661 cttttttgcc ctcttccgca ctcatgcgcc cggcaaccac cacgccgcgc ttttgtcgcc
    12721 agaagaacca gtcgcgctgt ttttcacttt ccagacgagg cgcttcacgc agccacggct
    12781 tatcgtcctg ccaccagtcg cccagacgct gttgccagct aagcccggtg tcgtccattt
    12841 cgccatacag cggttcggca aacggacagt tgatatggac tccaccagca tgaagcgtac
    12901 cgagagcgtg gtcgatggta gaaaccagcc aacgtgcggg gatatcctgg gtcgggcgcg
    12961 gcaatgaaat actgtgcgtg gggtgagagg cgaacattcc cggctgacga atcgcctgat
    13021 tcgcgccgca gtcaatgagc tccggcgggc gatcggcggt taacaggatc agtttttctc
    13081 cggttaaccc ggcttcaatc agtgccggat agagatttgc taccgccgtg ccggaggtca
    13141 caatcacagc caccggctgc ttgctgactt tcgccagccc cagcgccaga tgccccagtc
    13201 cacgctcatc gaaatgggtg tggtgaatga atgcggaatt ctccgccgcc gctaacgtta
    13261 acggtgtaga acgcgagcca ggggcgatac agatgtgtct gacgccgtga cgcgttaatg
    13321 cttccagaat gaccgccgcc cagcgtcggt taaatgcgct tactgacatg agtttgtccg
    13381 gtatcaatat tgcggctaag tataaggagc tacaaaaata gattattgat atgaatcggt
    13441 aatgatgcga ctcattacta ttccatttgt aataaagtac gcagccctgc cgctttgttg
    13501 tcgatttcct gccactcttg ctcggggtcg gaaccacgga caatgcccgc gccagcatat
    13561 agccgcacga cattgccgct aatttttgct gagcgcaggg aaacgcagaa ttcgctttgt
    13621 tgtaatgaga gatagcccgc agaaccggcg taccattctc gggtgaacgg ttcgtgacgg
    13681 gcgataaact gtcgcgccag atcgcgcggt aagccagcaa ctgctgccgt tggctgcaac
    13741 tgatgtaaac agatcacatc atccgctttg ttgagtgcag tccagataca gcggcgaaga
    13801 tgctgcactt tacgcagacg cagtacctgc ggcggtaaaa catccaacgt ctgggtatcg
    13861 gcctgcaatc gttggcagat atcctccacc accaacatgt tctcgcgctg gtttttatca
    13921 tccgccatca gccactcacc caaccgctgc gcctgcttat catcaggatg atttgctacc
    13981 gttcccgcca gcgcttcagt acgcagcgct ttgtcacgcc gccgccataa tcgttccggt
    14041 gaagagccaa gaaaagcatt ttcgccatca aaggccatgt aaaaatggta gcaattcaga
    14101 ttcagtcgac gactggcagc catcatcgcc gccgcattga ccggacttgc gaaatgcagg
    14161 tcagttgccc gagcaagcac cactttgtcg agctcacctt cggcgatggt tttcgttgcc
    14221 agttcgatta attgcgtcca ccccgttttg tccggccagt gttgttctcg ggtggtggtt
    14281 aaatgtaacc caggcaaggg tttaatactc accagtgtgg cgataaattc ttttgcctta
    14341 atcgcatcat gctgaaggga tctttcgctg aatagcgtca gccgcagcgt ggctttaccg
    14401 ccacagcgtc gccattccag gcgtggtaaa agtaaattgc cctgcgacgg gtcaaacgca
    14461 ttcaaccccc agatgcgtaa gtcggcgtgt tccgggtgct ggcgaagaaa acgttgtgcc
    14521 tggtccaacg acgtaaaacg ggttatcgca cccaggacgg cagcttcttc atcaccatta
    14581 cgttgttgcc agtagaattg cggatacacc tgctgactgg ccagccagct caaggcatca
    14641 aaagcgtctt tgagagggaa aggaatatcg ataacccgaa tgccgggtgt cgccggaatc
    14701 tcttgcgaca aatggcgcag tagattttcc agcgccgtag taagtgattg cacgcggacc
    14761 tctccctgtt aaaagcctca cattatacgg ggtacgacaa aaaaaatgca gtaccccggt
    14821 gtagggaggt tttaacggcg tgccagcaac agtcctagta ccagcccaac ggccgcaccc
    14881 acaccaattc cttgccaggg tttttcgtgg acgtagtcat cagcacgata aactgcctgc
    14941 ttcgcccgat agtaataact gtctgaagcc tggctaaccc gttttttcac atcatccagc
    15001 gctttttctg cacgcgcttt cagctcaaca tatttctgat cggcgggatc gccagaggag
    15061 cggagcacct cttccagtgt ttcactaagc agcgtcaggt cgtcatcgat acgtgtatca
    15121 ccaaactgat tagacattct cgttctccat ttgcgtaaaa cctgtcacta actatagaca
    15181 atggttattg attacgcctg aattacctcg cgtgccatcc caatgtgtgg gataccatct
    15241 tcttcataga cctccgtcac agggataaag ccaaaactct ggtagaagtt ttgcagatgc
    15301 gcctgcgccc cgaggtaaac aggtttatca ggccagtgac gcgtacatgt ttcgagtgtt
    15361 ttactcatca gctgctgccc cactttttcg ccacgcaacg cttcactgac aatcacccga
    15421 ccaataacga ccggctcaag atcatcatca cttttcagaa tcctcgcata cgccaccagt
    15481 tcatcatttt tccaaccgag aatatggcga ttatccctcg tcaaatcatc accatcgata
    15541 tcctgataag ggcaattctg ctcaacaaca aaaaccgcgc aacgcagttg taataaggca
    15601 taaagctggg aaaccgataa ttcagagtga tgcagatctt gccattcaat cataatgctc
    15661 tccttttaga tgtatgcctt atactagccg gaatattttt tgaaacgtga tgaactcatg
    15721 gaattaattt ttttaggtac ttcagccggt gtgccaaccc gtacgcgcaa tgtcacggca
    15781 atattgctta acctgcaaca tccgacccag agcggtcttt ggttgtttga ctgcggtgaa
    15841 ggcacccagc atcagctact gcataccgcc tttaaccctg gaaaactgga caagattttt
    15901 atcagtcacc ttcatggcga tcatctcttt ggtttacccg gcttgctgtg cagtcgttct
    15961 atgtctggta ttgtccaacc cttaacgatt tatggtccgc aaggtatccg tgaatttgtg
    16021 gagaccgcgc tgcggattag cggctcatgg accgattatc cgctggaaat tgtcgaaatt
    16081 ggcgctggcg aaattttcga tgatggcctg cgcaaagtga ccgcttatcc gctggaacac
    16141 ccactggaat gctatggcta tcgtattgaa gaacatgata aaccgggtgc attaaatgcc
    16201 caggcattaa aagctgctgg cgtaccgcct ggcccactgt ttcaggaatt aaaagcgggc
    16261 aaaacaatca tgctggaaga tggaaggcag attaacggcg cagattactt agccgctcca
    16321 gtaccaggta aagcgctcgc tattttcggc gataccggcc cctgcgatgc cgcacttgac
    16381 ctggctaaag gtgtcgatgt catggtgcac gaagcgacgc tggatataac catggaagcc
    16441 aaagccaata gtcgcggtca tagctctaca cgccaggctg cgacactggc ccgtgaggct
    16501 ggagtcggta agctaatcat tacccacgtc agctcgcgct atgatgacaa aggttgtcag
    16561 cacctgttac gtgaatgcag gtcaattttc ccggcgactg aactagcgaa tgatttcacc
    16621 gtgtttaacg tttaactctg cttattatta aaaacagggc gaaacttgcc ctgttatcgc
    16681 aacccgcgct acatatatcc ccccacacgg gcatattgag cgatttttga tatttattca
    16741 tctccttacg cactatattc agagcaataa gttgcctctt tttatcttca ttcagcacaa
    16801 cctttgcaac taaaaggagc ctataatggt tacagttgtc agcaattatt gtcaattatc
    16861 tcaaacccaa ctcagtcaga catttgcaga aaaatttact gtgaccgatg aattactgca
    16921 gtctttaaaa aaaacagcgt tatccggaga tgaagaaagt attgagttac tgcataacat
    16981 tgcgttaggt tatgatgaat ttgggaaaaa agctgaagat attctttacc atattgttat
    17041 aaacccaaca aatgaaaccc tatcgattat ccgacttatt aaaaatgcct gtttaaaatt
    17101 atataatttg gcacataccg caaccaaaca ccccctcaaa tcacatgatt cagatgatct
    17161 cctgttcaaa aaactattct ccccttcgaa attaatgaca attatcggtg aggacattcc
    17221 tcttatatc
//
LOCUS       DADXDL010000100        16998 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.100, whole genome shotgun sequence.
ACCESSION   DADXDL010000100 DADXDL010000000
VERSION     DADXDL010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16998)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16998)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16998
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.100"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            112..474
                     /locus_tag="IRB70_003955"
     CDS             112..474
                     /locus_tag="IRB70_003955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633808.1"
                     /translation="MNEFEKIFNEMNLDRALLPILFRSNRSTVWKYLSGDSTAPASAM
                     SLIMLLQLIQKRNPDLLAEWLTLSDFTIPPEVYLDQPDYWKGWVYTQHKVNKNVLEYL
                     KKHYPDEDQKSMGKGREE"
     gene            complement(577..1035)
                     /locus_tag="IRB70_003956"
     CDS             complement(577..1035)
                     /locus_tag="IRB70_003956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308578.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBC0633809.1"
                     /translation="MMELMVVHPHIFWLSLGGLLLAAEMLGGNGYLLWSGVAAVITGL
                     VVWLLPLGWEWQGVMFAVLTLLAAWLWWKWLSRRVREQKHSDSHLNQRGQQLIGRRFV
                     LESPLVNGRGHMRVGDSSWPVSASEDLSAGTHVEVIAIEGITLIIRAVIA"
     gene            complement(1032..1949)
                     /locus_tag="IRB70_003957"
     CDS             complement(1032..1949)
                     /locus_tag="IRB70_003957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH/Band 7/PHB domain protein"
                     /protein_id="HBC0633810.1"
                     /translation="MLIFIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPG
                     LSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVS
                     NLELAIINLTMTNIRTVLGSMELDEMLSQRDSINSRLLRIVDEATNPWGIKVTRIEIR
                     DVRPPAELISSMNAQMKAERTKRAYILEAEGIRQAEILKAEGEKQSQILKAEGERQSA
                     FLQAEARERSAEAEARATKMVSEAIASGDIQAVNYFVAQKYTEALQQIGSSSNSKVVM
                     MPLEASSLMGSIAGIAELVKDSANKRTQP"
     gene            2095..2772
                     /gene="fetA"
                     /locus_tag="IRB70_003958"
     CDS             2095..2772
                     /gene="fetA"
                     /locus_tag="IRB70_003958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter ATP-binding protein FetA"
                     /protein_id="HBC0633811.1"
                     /translation="MQENSPLLQLQNVGYLAGDAKILNNINFSLRAGEFKLITGPSGC
                     GKSTLLKIVASLISPTSGTLLFEGEDVSTLKPEIYRQQVSYCAQTPTLFGDTVYDNLI
                     FPWQIRNQQPDPAIFLDFLERFALPDTILTKNIAELSGGEKQRISLIRNLQFMPKVLL
                     LDEITSALDESNKHNVNEMIHRYVREQNIAVLWVTHDKDEINHADKVITLQPHAGEMQ
                     EARYELA"
     gene            2759..3538
                     /gene="fetB"
                     /locus_tag="IRB70_003959"
     CDS             2759..3538
                     /gene="fetB"
                     /locus_tag="IRB70_003959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308581.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron export ABC transporter permease subunit
                     FetB"
                     /protein_id="HBC0633812.1"
                     /translation="MNSHNITNESLALALMLVVVAILISHKEKLALEKDILWSVGRAI
                     IQLIIVGYVLKYIFSVDDASLTLLMVLFICFNAAWNAQKRSKYIAKAFISSFIAITVG
                     AGITLAVLILSGSIEFIPMQVIPIAGMIAGNAMVAVGLCYNNLGQRVISEQQQIQEKL
                     SLGATPKQASAILIRDSIRAALIPTVDSAKTVGLVSLPGMMSGLIFAGIDPVKAIKYQ
                     IMVTFMLLSTASLSTIIACYLTYRKFYNSRHQLVVTQLKKK"
     gene            complement(3601..4455)
                     /gene="cnoX"
                     /locus_tag="IRB70_003960"
     CDS             complement(3601..4455)
                     /gene="cnoX"
                     /locus_tag="IRB70_003960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308582.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperedoxin"
                     /protein_id="HBC0633813.1"
                     /translation="MSVENIVNINESNLQQVLEQSMTTPVLFYFWSERSQHCLQLTPI
                     LESLAAQYNGQFILAKLDCDAEQMIAAQFGLRAIPTVYLFQNGQPVDGFQGPQPEEAI
                     RALLDKVLPREEELKAQQAMQLMQEGNYTDALPLLKDAWQLSNQNGEIGLLLAETLIA
                     LNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVEENPEDAAL
                     ATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRKTFQEILAALGTGDALASKYR
                     RQLYALLY"
     gene            complement(4516..5325)
                     /gene="ybbO"
                     /locus_tag="IRB70_003961"
     CDS             complement(4516..5325)
                     /gene="ybbO"
                     /locus_tag="IRB70_003961"
                     /EC_number="1.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP(+)-dependent aldehyde reductase"
                     /protein_id="HBC0633814.1"
                     /translation="MTHKATEILTGKVMQKSVLITGCSSGIGLESALELKRQGFHVLA
                     GCRKADDVERMNSMGFTGVLIDLDSPECVDRAADEVIALTDNCLYGIFNNAGFGMYGP
                     LSTISRAQMEQQFSANFFGAHQLTMRLLPAMLPHGEGRIVMTSSVMGLISTPGRGAYA
                     ASKYALEAWSDALRMELRHSGIKVSLIEPGPIRTRFTDNVNQTQSDKPVENPGIAARF
                     TLGPEAVVDKVRHAFISEKPKMRYPVTLVTWAVMVLKRLLPGRVMDKILQG"
     gene            complement(5315..5938)
                     /gene="tesA"
                     /locus_tag="IRB70_003962"
     CDS             complement(5315..5938)
                     /gene="tesA"
                     /locus_tag="IRB70_003962"
                     /EC_number="3.1.1.5"
                     /EC_number="3.1.2.14"
                     /EC_number="3.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005225520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multifunctional acyl-CoA thioesterase I/protease
                     I/lysophospholipase L1"
                     /protein_id="HBC0633815.1"
                     /translation="MNFNNVFRWHLPFLFLVLLTFRAAAADTLLILGDSLSAGYRMSA
                     SAAWPALLNDKWQSKTSVVNASISGDTSQQGLARLPALLKQHQPRWVLVELGGNDGLR
                     GFQPQQTEQTLRQILQEVKATNAEPLLMQIRLPANYGRRYNEAFSAIYPKLAKEFDVP
                     LLPFFMEEVYLKPQWMQDDGIHPNRDAQPFIADWMAKQLQPLVNHDS"
     gene            5909..6595
                     /locus_tag="IRB70_003963"
     CDS             5909..6595
                     /locus_tag="IRB70_003963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0633816.1"
                     /translation="MPAENIVEVHHLKKSVGQGEHELSILTGVELVVKRGETIALVGE
                     SGSGKSTLLAILAGLDDGSSGEVNLVGQPLHNMDEEARAKLRAKHVGFVFQSFMLIPT
                     LNALENVELPALLRGESSVESRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARA
                     FNGRPDVLFADEPTGNLDRQTGDKIADLLFSLNREHGTTLIMVTHDLQLAARCDRCLR
                     LVNGQLQEEA"
     gene            6592..9006
                     /locus_tag="IRB70_003964"
     CDS             6592..9006
                     /locus_tag="IRB70_003964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0633817.1"
                     /translation="MIARWFWREWRSPSLLIVWLALSLAVACVLALGNISDRMEKGLS
                     QQSREFMAGDRALRSSREVPQAWLEEAQKRGLKVGKQLTFATMTFAGDTPQLANVKAV
                     DDIYPMYGDLQTNPPGLKPQAGSVLLAPRLMALLNLKTGDTIDVGDATLRIAGEVIQE
                     PDSGFNPFQMAPRLMMNLADVDKTGAVQPGSRVTWRYKFGGNENQLDGYEKWLLPQLK
                     PEQRWYGLEQDEGALGRSMERSQQFLLLSALLTLLLAVAAVAVAMNHYCRSRYDLMAI
                     LKTLGAGRAQLRKLIVGQWLMVLALSAVTGGAIGLLFENVLMVLLKPVLPAALPPASL
                     WPWLWALGTMTVISLLVGLRPYRLLLATQPLRVLRNDVVANVWPLKFYLPIVSVVVVL
                     LLAGLMGGSMLLWAVLAGAVVLALLCGVLGWMLLNVLRRMTLKSLPLRLAVSRLLRQP
                     WSTLSQLSAFSLSFMLLALLLVLRGDLLDRWQQQLPPESPNYFLINIATEQVAPLKAF
                     LAEHQIVPESFYPVVRARLTAINDKPTEGNEDEALNRELNLTWQNTRPDHNPIVAGNW
                     PPKADEVSMEEGLAKRLNVALGDTVTFMGDTQEFRAKVTSLRKVDWESLRPNFYFIFP
                     EGALDGQPQSWLTSFRWENGNGMLTQLNRQFPTISLLDIGAILKQVGQVLEQVSRALE
                     VMVVLVTACGMLLLLAQVQVGMRQRHQELVVWRTLGAGKKLLRTTLWCEFAMLGFVSG
                     LVAAIGAETALAVLQAKVFDFPWEPDWRLWIVLPCSGALLLSLFGGWLGARLVKGKAL
                     FRQFAG"
     gene            complement(9611..10705)
                     /gene="mnmH"
                     /locus_tag="IRB70_003965"
     CDS             complement(9611..10705)
                     /gene="mnmH"
                     /locus_tag="IRB70_003965"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-selenouridine(34) synthase MnmH"
                     /protein_id="HBC0633818.1"
                     /translation="MQERHTEQDYRALLIADTPIIDVRAPIEFEQGAMPAAINLPLMN
                     NDERAAVGTCYKQQGSDAALALGHKLVAGEIRQQRMDAWRAACLQNPQGILCCARGGQ
                     RSHIVQRWLHEEGIDYPLVDGGYKALRQTAIQATIELSQKPIVLIGGCTGSGKTLLVQ
                     QQPNGVDLEGLARHRGSAFGRTLQPQLSQASFENLLAAEMLKTDARQDLHLWVLEDES
                     RMIGSNHLPECLRERMTQAAIAVVEDPFEIRLERLNEEYFLRMHHAFTHAYGDEQGWQ
                     EYCEYLHHGLSAIKRRLGLQRYNELAAQLDTALTTQLTTGSTDGHLAWLVPLLEEYYD
                     PMYRYQLEKKAEKVVFRGEWAEVAEWVKAQ"
     gene            complement(10774..11700)
                     /gene="allS"
                     /locus_tag="IRB70_003966"
     CDS             complement(10774..11700)
                     /gene="allS"
                     /locus_tag="IRB70_003966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional activator AllS"
                     /protein_id="HBC0633819.1"
                     /translation="MFDPETLRTFIAVAETGSFSKAAERLCKTTATISYRIKLLEENT
                     GVALFFRTTRSVTLTAAGEHLLSQARDWLSWLESMPSELQQVNDGVERQVNIVINNLL
                     YNPQAVAQLLAWLNERYPFTQFHISRQIYMGVWDSLLYEGFSLAIGVTGTEALANTFS
                     LDPLGSVQWRFVMAADHPLANVEEPLTEAQLRRFPAVNIEDSARTLTKRVAWRLPGQK
                     EIIVPDMETKIAAHLAGVGIGFLPKSLCQSMIDNQQLVSRVIPTMRPPSPLSLAWRKF
                     GSGKAIEDIVTLFTQRRPEISGFLEIFGNPRS"
     gene            11930..12412
                     /gene="allA"
                     /locus_tag="IRB70_003967"
     CDS             11930..12412
                     /gene="allA"
                     /locus_tag="IRB70_003967"
                     /EC_number="4.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ureidoglycolate lyase"
                     /protein_id="HBC0633820.1"
                     /translation="MKLQVLPLSQEAFSAYGDVIETQQRDFFHINNGLVERYHDLALV
                     EILEQDRTLISINRAQPANLPLTIHELERHPLGTQAFIPMKGEVFVVVVALGDDKPDL
                     STLRAFITNGEQGVNYHRNVWHHPLFAWQRVTDFLTIDRGGSDNCDVESIPEQELCFA
                     "
     gene            12490..13305
                     /gene="allR"
                     /locus_tag="IRB70_003968"
     CDS             12490..13305
                     /gene="allR"
                     /locus_tag="IRB70_003968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional repressor AllR"
                     /protein_id="HBC0633821.1"
                     /translation="MTEVRRRGRPGQAEPVAQKGAQALERGIAILQYLEKSGGSSSVS
                     DISLNLDLPLSTTFRLLKVLQAADFVYQDSQLGWWHIGLGVFNVGAAYIHNRDVLSVA
                     GPFMRRLMLLSGETVNVAIRNGNEAVLIGQLECKSMVRMCAPLGSRLPLHASGAGKAL
                     LYPLAEEELMSIILQTGLQQFTPTTLVDMPTLLKDLEQARELGYTVDKEEHVVGLNCI
                     ASAIYDDVGSVVAAISISGPSSRLTEDRFVSQGELVRDTARDISTALGLKAHP"
     gene            13395..15176
                     /gene="gcl"
                     /locus_tag="IRB70_003969"
     CDS             13395..15176
                     /gene="gcl"
                     /locus_tag="IRB70_003969"
                     /EC_number="4.1.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308595.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate carboligase"
                     /protein_id="HBC0633822.1"
                     /translation="MAKMRAVDAAMYVLEKEGITTAFGVPGAAINPFYSAMRKHGGIR
                     HILARHVEGASHMAEGYTRATAGNIGVCLGTSGPAGTDMITALYSASADSIPILCITG
                     QAPRARLHKEDFQAVDIEAIAKPVSKMAVTVREAALVPRVLQQAFHLMRSGRPGPVLV
                     DLPFDVQVAEIEFDPDMYEPLPVYKPAASRMQIEKAVEMLIQAERPVIVAGGGVINAD
                     AAALLQQFAELTSVPVIPTLMGWGCIPDDHELMAGMVGLQTAHRYGNATLLASDMVFG
                     IGNRFANRHTGSVEKYTEGRKIVHIDIEPTQIGRVLCPDLGIVSDAKAALTLLVEVAQ
                     EMQKAGRLPCRKEWVADCQQRKRTLLRKTHFDNVPVKPQRVYEEMNKAFGRDVCYVTT
                     IGLSQIAAAQMLHVFKDRHWINCGQAGPLGWTIPAALGVCAADPERNVVAISGDFDFQ
                     FLIEELAVGAQFNIPYIHVLVNNAYLGLIRQSQRAFDMDYCVQLAFENINSSEVNGYG
                     VDHVKVAEGLGCKAIRVFKPEDIAPAFEQAKALMAQYRVPVVVEVILERVTNISMGSE
                     LDNVMEFEDIAYNAVDAPTETCFMHYE"
     gene            15189..15965
                     /gene="hyi"
                     /locus_tag="IRB70_003970"
     CDS             15189..15965
                     /gene="hyi"
                     /locus_tag="IRB70_003970"
                     /EC_number="5.3.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxypyruvate isomerase"
                     /protein_id="HBC0633823.1"
                     /translation="MLRFSANLSMLFGEYDFLARFEKAAQCGFRGVEFMFPYDYDIEE
                     LKQVLASNKLEHTLHNLPAGDWAAGERGIACIPGREEEFRDGVAAAIRYARALGNKKI
                     NCLVGKTPTGFSSEQIHATLVENLRYAANMLMKEDILLLIEPINHFDIPGFHLTGTRQ
                     ALKLIDDVGCCNLKIQYDIYHMQRMEGELTNTMTQWADKIGHLQIADNPHRGEPGTGE
                     INYEYLFTVIENSDYNGWVGCEYKPQTTTEAGLRWMDPYR"
     gene            16065..16943
                     /gene="glxR"
                     /locus_tag="IRB70_003971"
     CDS             16065..16943
                     /gene="glxR"
                     /locus_tag="IRB70_003971"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBC0633824.1"
                     /translation="MKLGFIGLGIMGTPMAINLARAGHQLHVTTIGPVADELLSLGAV
                     SVETARQVTEASDIIFIMVPDTPQVEEVLFGENGCTKASLKGKTIVDMSSISPIETKR
                     FARQVNELGGDYLDAPVSGGEIGAREGTLSIMVGGDEAVFERVKPLFELLGKNITLVG
                     GNGDGQTCKVANQIIVALNIEAVSEALLFASKAGADLVRVRQALMGGFASSRILEVHG
                     ERMIKRTFNPGFKIALHQKDLNLALQSAKALALNLPNTATCQELFNTCAANGGSQLDH
                     SALVQALELMANHKLA"
BASE COUNT         3977 a         4242 c         4575 g         4204 t
ORIGIN      
        1 aataaattct gtttctggac taaacgtgaa gcggttcctg atgtgtgcta aaatgcgttt
       61 ctttgataaa tctcaatttt taagaggttt acgccaggca ggaaaattta aatgaatgaa
      121 tttgagaaga tttttaatga aatgaatctg gaccgggcat tgttaccgat cctttttcgt
      181 tcgaaccggt cgacagtgtg gaagtattta agcggcgata gtacggctcc tgcctctgcc
      241 atgtcgctga tcatgctgtt gcagttgatc cagaaacgaa accccgatct gttagccgaa
      301 tggttaacgc tttctgattt caccattccg ccagaagttt acctggacca acctgattac
      361 tggaaagggt gggtgtatac ccaacacaag gtcaataaaa acgtcctgga atatctaaaa
      421 aaacactatc cggatgaaga ccaaaaaagt atgggtaaag gccgggaaga gtaattttgc
      481 ctctactcgg ctatatgccg gatgcggcgc aagcgcctta tctggcctac gattcgggca
      541 tattttgtag gcatgataag acgcgccagc gtcgcatcag gcgatgaccg cacggataat
      601 cagcgttatc ccttctatcg caatcacctc aacatgcgta cctgcactga gatcctcgct
      661 ggcgctgaca ggccatgaac tgtcaccgac gcgcatatga ccacgcccgt tgaccagcgg
      721 agattccaga acaaaacgtc ggccaatcaa ctgctgcccg cgctggttta aatgactgtc
      781 gctgtgcttt tgttcgcgca cccgccgcga caaccatttc caccacagcc aggcggcgag
      841 cagcgtcagg acggcaaaca ttaccccttg ccactcccaa cccagcggca gcaaccagac
      901 caccagaccg gtaatcaccg ctgccacgcc gctccacaac agataaccat tgccgcccaa
      961 catctcggct gccagcagca aaccgccgag acttagccag aaaatatgtg gatgaacgac
     1021 cattaactcc atcatggctg agtccgtttg ttggcgctgt ctttcaccag ctcggcaatc
     1081 ccggcaatcg accccatcag gctgctggcc tctaatggca tcatcactac tttgctgtta
     1141 ctggacgaac cgatctgctg taacgcttcg gtgtatttct gtgcgacgaa gtagttcacc
     1201 gcctgaatat caccggaggc aatggcttca gataccattt tggtggcgcg ggcttctgct
     1261 tcggcagaac gttcacgcgc ttcggcctgt aagaatgccg attgacgttc accttccgct
     1321 ttcaggattt gcgactgttt ttcaccttca gctttgagga tttccgcctg acggatccct
     1381 tccgcttcaa ggatgtaagc gcgtttggta cgttccgctt tcatctgcgc gttcattgaa
     1441 gagataagct ctgccggtgg gcgcacgtcg cgaatttcaa tacgggtgac tttaatcccc
     1501 cacgggttgg tggcttcatc gacaatacgc agcaggcgtg agttgatgct gtcgcgctga
     1561 gagagcattt cgtcaagttc cattgaaccc agcacggtac ggatgttagt catggtcagg
     1621 ttgatgatcg ccagctccag attgctgact tcataagccg cgcgcggcgc gtcaatcacc
     1681 tgaataaagc acacggcgtc gatggtaacg ttggcgttat ctttcgagat aacttcctgg
     1741 gaagggatat cgagcacttg ctccatcata ttgatcttgc gaccaatgcg atccataaac
     1801 ggcaccacca gactgagccc cggctgtaac gttttggtat agcgaccaaa acgttctact
     1861 gtccactgat agccctgcgg cacgattttg acgcccgcgc cgacaatgac cagcgcgaca
     1921 aaaatgagaa tcgggataaa gataagcatc ggaaaaacct cctgttgtac cgtccataat
     1981 cagcaaaatt gctgcttgat taaacaaatt atacctgatt actgaaagag agttccccct
     2041 tattcctgcg aaggataaac tgtttttagt aaaaatcaga aaaagggaac agtgatgcag
     2101 gaaaatagtc ctttgcttca gctacaaaac gtaggatatc tggcgggtga tgcgaagatt
     2161 cttaataaca tcaatttttc gctgcgtgct ggcgaattta agttaattac cggtccttct
     2221 ggttgtggca aaagtacgct gctaaaaata gttgcttcat tgatcagccc aaccagcgga
     2281 acgttactgt ttgaaggtga ggatgtcagc acactaaagc cagaaatcta ccgccagcaa
     2341 gtctcttatt gcgcccagac gccgacgctg tttggcgaca cggtatacga taatctgatc
     2401 tttccttggc agatccgtaa ccagcagcct gacccagcca tttttctcga ttttctcgaa
     2461 cgcttcgcct taccggacac cattttgacg aagaatatcg ccgagctatc tggtggggaa
     2521 aaacaacgca tctcattgat tcgtaacctg caatttatgc cgaaggtttt attgctggat
     2581 gaaataacca gtgcgctgga cgaaagtaat aaacataacg ttaatgagat gatccaccgt
     2641 tatgtgcgcg agcaaaatat tgccgtgctg tgggtgacac acgataaaga cgaaattaat
     2701 catgcggata aagtgattac actgcaaccg catgccggag aaatgcagga agcacgctat
     2761 gaactcgcat aatattacta acgaatcatt agcactggca ttgatgctgg tggtggtggc
     2821 aatcttaatt agccataaag aaaaactggc gctggagaaa gatattctct ggagcgtcgg
     2881 gcgcgcgata atccagctga ttattgtcgg ctatgtgctg aagtatattt tcagcgtgga
     2941 tgatgccagc ctgacattat tgatggtgtt atttatctgc tttaatgcgg cgtggaatgc
     3001 gcaaaaacgc agtaaatata ttgctaaagc ttttatctca tcgtttattg ccattacggt
     3061 cggggcggga attaccctgg cggtgctgat tctctcaggg tcgattgaat ttatcccgat
     3121 gcaggtgatc cctatcgccg ggatgatagc cggtaacgcc atggtagcgg tggggttgtg
     3181 ttacaacaat ttagggcaac gggtgattag cgaacagcaa cagattcagg agaaactgag
     3241 tcttggcgcg acgccgaaac aggcttcagc gatattgatt cgcgacagta ttcgcgctgc
     3301 tttaattccg acggtcgatt cagcaaaaac ggtaggctta gtgagtttac caggaatgat
     3361 gtccgggctg atatttgccg ggattgatcc ggtgaaggcg attaaatatc agattatggt
     3421 gacctttatg ctgctctcaa ccgccagcct gtcgaccatt attgcctgct atttaaccta
     3481 tcgtaagttt tacaattcgc gccaccagtt ggtggtgacg caattgaaga agaaatgatg
     3541 caatgccgga tgcgcagcat cgcatccggc gttgtggttc atgtgccgat caacggaaac
     3601 tcaatacaac aacgcatata actggcggcg atacttcgac gccagcgcat cacctgtacc
     3661 cagcgcagcg aggatctcct ggaacgtttt acgcgtctga ccgtctgcgg cggtgagatc
     3721 tttacgcaga tgcccaaaca gtaactccag cgcctcttca ttgcgcccaa cctggtgcaa
     3781 ttgcagcgcc agttgcgtcg ccagtgcggc atcttctgga ttctcctcca cctgctgttg
     3841 caactgttga atttccggcg tatcagccgc ctgcttcagc agttcgattt gcgccaccag
     3901 cccctggtag cgggtgtcct gatcctgcaa cggaatggtt ttcagcaccg cttccgcatc
     3961 ttcagaacgg ttcagcgcaa tcagcgtttc tgccagcagc aggccgatct ccccgttctg
     4021 attcgacaac tgccaggcgt ctttcagcaa tggcagggcg tcggtgtaat tgccttcctg
     4081 catcagttgc atcgcctgct gcgctttcag ttcttcttcg cgcggcagca ctttatccag
     4141 cagggcgcgg atcgcctctt ccggttgcgg cccctggaag ccgtctaccg gttgcccgtt
     4201 ctggaacaga tacacggtcg gaatcgcgcg cagaccaaac tgggcggcaa tcatctgctc
     4261 cgcgtcgcag tccagcttcg ccagaataaa ttgcccgttg tactgcgccg cgaggctttc
     4321 cagaattggg gttaactgca aacagtgctg gctacgttca gaccaaaaat agaacagcac
     4381 cggagtggtc atcgactgtt caagaacctg ttgcaggtta gattcgttaa tgttgacaat
     4441 attttctacg gacatggagt cgctctctgt tgtcgatatt ttctttgaca tgggggctta
     4501 agcgcgcgct tcaactcacc cctgcaatat tttgtccatc acgcgccccg gcagcaggcg
     4561 cttaagcacc attactgccc aggtcaccag cgttaccgga tagcgcatct tcggcttctc
     4621 gctaataaaa gcatggcgca ctttgtcgac caccgcttcc ggtcctaacg taaagcgggc
     4681 ggcgatgccg ggattttcga ctggtttatc actttgcgtc tggttgacgt tgtcggtgaa
     4741 gcgagtacga atgggaccag gttcgatcag gctgacttta attccgctgt ggcgcagctc
     4801 catgcgcagt gcgtctgacc acgcctccag cgcatattta ctggccgcgt aagcgccacg
     4861 acccggtgtg gagattaatc ccatcaccga tgaggtcatc acaatacgcc cttcaccgtg
     4921 cggcaacatc gcgggtaaca ggcgcatggt gagctggtgt gcgccgaaaa agttggcgga
     4981 aaactgctgt tccatctgcg cacggctgat ggtggaaagg gggccataca tgccgaatcc
     5041 ggcattgtta aagatcccat acagacaatt atcggtcagg gcgatcactt cgtcggctgc
     5101 gcgatcaaca cattctggcg aatccagatc gatcaacacg ccggtaaatc ccatgctgtt
     5161 catgcgctca acatcatccg ctttccggca acctgccagc acatgaaaac cctggcgttt
     5221 taattcgagc gcgctttcca ggccaattcc actggaacat ccggtaatta agaccgattt
     5281 ttgcataact ttacctgtca ggatctccgt tgctttatga gtcatgattt actaaaggct
     5341 gcaactgctt cgccatccag tcggcaataa acggctgggc gtcgcggttg ggatgaatac
     5401 cgtcatcctg catccattgt ggtttgaggt agacctcttc cataaaaaag ggcagcagcg
     5461 gaacatcaaa ctctttggcg agtttggggt aaatggcgct aaaggcttca ttataacggc
     5521 gaccatagtt tgcaggcaga cgtatttgca ttaacaatgg ttcagcgttg gtggctttga
     5581 cctcctgcaa aatctggcgc agcgtttgct cggtttgttg tggctgaaaa ccacgcaaac
     5641 cgtcattgcc gcccagttca accagcaccc aacgcggctg atgctgtttc agcagagccg
     5701 gaaggcgcgc cagcccttgt tgcgaggtgt cgccgctgat gctggcattg actaccgacg
     5761 ttttactctg ccacttatca ttcaacaagg caggccaggc cgcgctggca gacattcgat
     5821 acccggcgct caggctatca cccagaatca ataacgtgtc cgctgcagcg gcacggaagg
     5881 ttaacaggac caggaacagg aagggcaaat gccagcggaa aacattgttg aagttcatca
     5941 tcttaagaag tccgtcggtc agggggagca tgaactctcc atcctcaccg gagttgagct
     6001 ggttgtcaaa cgtggcgaga ccatcgcgct ggtgggcgag tcgggatcgg gtaagtcaac
     6061 cttgctggcg atcctcgccg ggctggatga cggcagcagt ggcgaagtaa atctggtggg
     6121 acaaccgcta cataatatgg acgaagaagc gcgggcaaag ttacgcgcga agcacgtagg
     6181 ttttgttttt cagtcattta tgttaattcc tacccttaac gcgctggaaa acgtcgagct
     6241 tccggcgctg ctgcgcggtg aaagtagcgt ggaaagtcgt aacggggcaa aagcgttgct
     6301 cgaacagtta ggactgggta aacgtctgga tcatcttccg gcacagcttt ccggcggcga
     6361 acagcaacga gtggcgctgg cgcgagcttt taatggtcgg cctgatgtgc tgtttgccga
     6421 cgaacccacc ggcaatcttg accgccagac gggcgataaa attgccgacc tgctgttttc
     6481 cctcaaccgt gaacatggca ccacgttgat tatggtgacc cacgacctgc aactggcggc
     6541 acgctgcgac cgctgcttac ggctggtgaa cgggcagttg caggaggaag catgattgca
     6601 cgttggttct ggcgcgaatg gcgctcgccg tcgctattaa ttgtctggct ggcgctaagc
     6661 ctggcggtgg cctgcgtgct ggcgctgggc aatatcagcg atcgcatgga gaagggctta
     6721 agccagcaaa gccgggagtt tatggcgggc gatcgggcgt tgcgcagttc gcgcgaagtg
     6781 ccgcaagcgt ggctggagga agcgcaaaag cgcggcctga aagtcggcaa gcagctgact
     6841 ttcgccacca tgacatttgc aggcgacaca ccgcagctgg cgaacgtcaa agcggtggat
     6901 gatatctacc cgatgtatgg cgatctgcaa accaatcccc caggcctgaa accgcaggcg
     6961 ggcagcgtat tgctggcccc acgcctgatg gcactgctta acctgaaaac gggcgacacc
     7021 attgacgtgg gcgatgccac cttgcggatt gccggagaag tgattcagga accggattcc
     7081 ggttttaacc ccttccagat ggctccgcgt ctgatgatga atctggcgga tgtcgataaa
     7141 accggagccg tgcagccggg aagtcgggtc acctggcgct ataaattcgg cggcaacgag
     7201 aaccagctcg acggctatga gaaatggttg ttaccccagc ttaaacccga acaacgctgg
     7261 tacggtctgg aacaggacga aggcgcgctg gggcgctcga tggaacgctc gcaacagttc
     7321 ctgctgcttt cggcgcttct gaccttgctg ctggcagtgg cagcggtggc ggtggcgatg
     7381 aatcattact gtcgcagtcg ctacgatctg atggcgatcc tcaaaacgct gggagcaggg
     7441 cgagcgcaat tgcgtaagtt aatcgtcggt cagtggttga tggtgctggc gctttcagcc
     7501 gttaccggtg gtgcgatagg cctgttgttc gaaaacgtgt tgatggtgct gctcaagccc
     7561 gttttgcctg ctgcactacc gccagccagc ctctggccgt ggttgtgggc gctgggcacc
     7621 atgacggtca tctcgctgct ggtggggcta cgaccgtacc gcttgttgct ggcaacgcag
     7681 cctttacgcg tattacgtaa tgatgtggtc gcgaacgtct ggccgctgaa gttttatctg
     7741 ccgattgtca gtgtggtggt tgtgctgctg ctcgccggat taatgggtgg cagcatgctg
     7801 ctttgggcgg tgctggcggg cgcggtagta ctggctttgc tgtgcggtgt gctgggctgg
     7861 atgctgctga atgtacttcg ccgcatgacg ctgaaatcgc tacctctgcg cctggcggtt
     7921 agccgcctgt tacgtcagcc gtggtcaacg ttaagccagc tttcggcatt ttcgctctcc
     7981 tttatgctgc tggcgctgtt gctggtattg cgtggcgatc tgctcgaccg ctggcagcag
     8041 cagctacctc cagaaagccc gaactacttt ttaattaaca tcgccacaga acaggtagca
     8101 ccgctaaaag cgttcctcgc ggaacatcag atagtcccgg aatcgtttta tccggtggtg
     8161 cgggcgcggc tgacggcgat taacgataag ccgacagaag gcaatgaaga tgaggcgctc
     8221 aatcgcgaac tcaatcttac ctggcaaaat acgcggcccg atcataatcc gattgtcgcc
     8281 ggtaactggc cgccaaaagc cgatgaagtg tcgatggaag aggggctggc gaaacgctta
     8341 aacgttgccc tcggtgatac cgtgactttt atgggcgata cccaggagtt ccgcgctaaa
     8401 gtgaccagcc tgcgcaaagt ggactgggaa agtctgcggc ctaatttcta ttttattttc
     8461 cctgaagggg cattagacgg gcaaccgcag agctggctta ccagtttccg ctgggagaat
     8521 ggcaacggca tgttgacgca actcaaccgc cagttcccta ctattagcct gttagacatt
     8581 ggcgcgattt taaaacaggt cggtcaggtg ctggagcagg taagtcgggc gctggaggtg
     8641 atggtggtgc tggtcaccgc ctgcggtatg ttgctgttgc tggcacaggt gcaggtggga
     8701 atgcgtcagc gtcatcagga gctggtggtg tggcgcacac tcggtgcggg gaaaaaactg
     8761 ctgcgtacca cgttgtggtg tgagttcgcc atgcttgggt ttgtttctgg cctggtagcc
     8821 gcaattggtg cggaaacggc gctggcagtg ttgcaggcga aagtgtttga ttttccgtgg
     8881 gagccagact ggcgattgtg gattgtgctg ccgtgcagcg gtgcactgct gctgtcgctt
     8941 ttcggcggct ggctgggtgc gcgattggtt aagggtaagg cgctgttcag gcagtttgcg
     9001 gggtgatgac aggcgttaga ttgcctgatg cgctacgctt atcaggccta cgaggatcgt
     9061 gcaatatatt gattttgcaa gattgtgtag gccggataag gcgtttacgc cgcatctggc
     9121 atgaacagtg tgcattttgg caataaatat gaaaccaact gtcatgtcgg tttttttaaa
     9181 ggccgaaggt ggtaaacctt cggccttagc tacgtttcct cagttattca ataaactgac
     9241 ggatcagttc cagcagcgcg attagcgcct taagaatgat gagaactgcc tctctccaaa
     9301 ttagagcacc agaatcagca ccacctgtat cctgaccagg acttaaaagt acttttccgc
     9361 actgcggtaa tcccttgagg cagtatcact actagcgtcg ggattgtatc gccaacatag
     9421 ctgtttgaat atgtaggcat cctgacttat aattcatttg ctagatgagg actgtttcat
     9481 ttctgcccgg aaccaccaag tcttgggcgg aaaaaataaa aaaaccgact gtcatgtcgg
     9541 tttttttata tctgtattct ggtgcaacca ttttgttctc acgacaatcg ccgtttcaga
     9601 ataccgccca tcactgcgcc ttaacccatt ccgccacttc cgcccactca ccgcgaaaga
     9661 caactttttc agcttttttc tcaagctgat agcgatacat cgggtcgtaa tattcttcaa
     9721 gtaacggcac cagccaggcc agatgaccgt cggtgctgcc ggtggtgagt tgcgttgtca
     9781 gcgccgtatc cagctgggca gcgagttcgt tatagcgctg taaccccagc cgacgcttaa
     9841 tcgccgaaag tccgtgatgc aggtattcgc aatactcctg ccagccctgt tcgtcgccgt
     9901 acgcatgggt aaaagcatga tgcatacgca agaaatattc ttcgttcagg cgttcaagac
     9961 ggatctcaaa cggatcttct accaccgcaa tcgccgcctg agtcattcgc tcgcgcagac
    10021 attccggcag gtgattcgaa ccgatcatcc ggctttcatc ttccagcacc cacaggtgca
    10081 aatcctgacg ggcgtcggtt tttagcattt cggcagccag cagattttca aaactcgcct
    10141 ggctaagttg tggttgtaac gtgcgaccaa acgccgaacc gcgatggcgc gccaaccctt
    10201 ccagatcaac accgttcggc tgttgctgca ctaacagcgt tttaccgctg ccagtacaac
    10261 cgccaatcag cactatcggt ttttgtgaca gttcaatggt cgcctgaatc gcggtctggc
    10321 gcagtgcctt ataaccgccg tctaccagcg gataatcaat cccctcttca tgcaaccagc
    10381 gttgcacaat atgtgaacgt tgaccgccac gggcgcagca gagaatacct tgcggatttt
    10441 gcaggcacgc tgcccgccag gcgtccatac gctgctgacg aatttcaccc gccaccagtt
    10501 tatgacccag cgccagcgcc gcgtctgacc cttgctgttt atagcaggtg ccaacggcgg
    10561 cgcgttcatc gttattcatt aacggcaggt tgatagcggc aggcattgcg ccttgctcaa
    10621 actcgatggg ggcgcgaaca tcaataatgg gcgtatcagc aatcagcagg gcacgatagt
    10681 cctgttccgt gtgtctctct tgcatagtaa aaagtgaacc tcaaatcagc ttgcgcgcta
    10741 ttttacgcgc caacgcgcaa ggaaacttga tttttaactg cgtgggttgc cgaaaatttc
    10801 taaaaatccg ctgatttccg gcctgcgctg ggtaaacaag gtcacaatat cttctatcgc
    10861 tttgccgctg ccaaatttgc gccatgccag actcaatggt gaaggagggc gcatcgttgg
    10921 gattacccgg ctgaccagtt gttgattatc gatcattgac tggcaaagtg attttggcaa
    10981 aaaaccaatg ccaacgcccg ccagatgggc ggcgattttc gtttccatat cgggaacaat
    11041 aatctctttt tgccccggca atcgccaggc gacgcgtttg gttagtgtgc gggcgctgtc
    11101 ttcaatatta accgccggaa agcgccgcaa ctgtgcttct gttagcggct cttcaacgtt
    11161 cgccagcgga tgatccgccg ccatgacaaa gcgccattgc accgatccta agggatcaag
    11221 actaaaggta tttgccagcg cctcggttcc cgtgacgccg atagccagtg aaaaaccttc
    11281 gtataatagc gaatcccaga cgcccatata gatttgtcgg gagatgtgaa actgggtaaa
    11341 ggggtaacgc tcattcagcc acgccagcaa ctgggcgacg gcctgggggt tatagagcag
    11401 gttgttgatg acaatattca cctggcgttc cacgccatca ttcacctgtt gcagctcgct
    11461 tggcatactt tccagccagc tcagccagtc tctggcctgg gaaagtagat gctcgccagc
    11521 cgctgtcaac gtcacgctgc gagtcgtgcg gaaaaacagc gccactccgg tgttctcttc
    11581 cagaagttta atgcgataac tgatcgtcgc cgtggtttta cataatcgtt ctgccgcttt
    11641 tgaaaaactt cctgtttcag caaccgcaat gaaagtccgt aaggtttctg gatcgaacat
    11701 cttcaggtat ccccttttaa atccgcaagt tgcgtgattt tcttatcctc tgatttatca
    11761 gtatttttac atgataaccc tgttcaattt gtggactaaa tctagttttg gaaaaatatt
    11821 ccaacttttg tattgatgtt gttctcttaa ggttttagat tgcctgttat tgaaaccaag
    11881 ctgaccggtc ggcggtggtt gaacggaatt atgttacaag gacaaaaaga tgaaacttca
    11941 ggtattaccg ttaagtcagg aagcctttag tgcttatggc gacgtaatcg aaacgcagca
    12001 acgggatttt ttccatatta acaatggcct ggtggagcgt taccacgatt tggcgctggt
    12061 tgagattctt gagcaagacc gtacgcttat cagcattaac cgagcgcaac cggcgaatct
    12121 gccgctgacc attcacgaac tcgaacgtca tccgctgggt actcaggcct ttatcccgat
    12181 gaaaggtgaa gtgtttgtgg tagtcgtggc gttaggtgac gacaaaccag acctgtcaac
    12241 gctgcgggcg tttattacca acggtgaaca gggggtgaat taccatcgta acgtctggca
    12301 tcacccactt ttcgcctggc agcgcgtcac cgattttctg accatcgatc gcggcggcag
    12361 tgacaactgt gatgttgaaa gtattcctga acaggaactc tgttttgcgt gacgcctgca
    12421 accgacttgc ataagataaa cgaattgttc attgtttatg ctcacttgta ggtcggagtt
    12481 aacgtaggta tgacggaagt tagacggcgc ggcaggccag gacaggcgga gcctgtggca
    12541 cagaagggcg cacaggcgtt agagcgggga attgcgattc tgcaatatct ggaaaaaagt
    12601 gggggaagtt cgtcggttag cgatatttct ctcaatctgg atttgccgct ctccacgacc
    12661 tttcgcttgc tgaaggtttt acaggcagcg gattttgtct atcaggacag tcagttaggc
    12721 tggtggcata taggattagg tgtctttaac gtcggtgcag cgtacatcca taaccgcgat
    12781 gtcctctccg tcgccgggcc gtttatgcgc cgcctgatgt tactttccgg cgaaacggtc
    12841 aatgtcgcga tccgtaacgg caatgaagca gtattaattg gtcagttaga gtgtaaatcg
    12901 atggtcagga tgtgtgcgcc actgggcagt cgtctgccgc tgcatgcttc cggtgcgggc
    12961 aaggcgttgc tttatccgct ggcggaagag gagttgatga gcatcattct gcaaaccggt
    13021 ttgcagcagt ttacgccaac gacgcttgtg gatatgccca ccttgctgaa ggacctggaa
    13081 caagcgcgtg aactgggcta taccgtagat aaagaagagc atgttgtagg tctgaattgc
    13141 atagcttcag caatttacga tgatgtcggt agcgttgttg ccgctatctc catctccggg
    13201 ccttcatcaa gactgacaga agatcgtttt gtcagtcagg gtgagctggt cagagacacc
    13261 gcccgcgata tcagcacggc gttgggactg aaagcacatc catagtgtct gtcgcatccc
    13321 gctctgcgga gcgggttttt ttgacaaaat ttgaaagttg gaaaattttt ccaattaata
    13381 gaggtaggaa taaaatggca aaaatgagag ccgttgacgc ggcaatgtat gtgctggaga
    13441 aagaaggtat caccaccgcc ttcggcgttc cgggagctgc aatcaatccg ttctactcag
    13501 cgatgcgtaa gcacggcggt attcgtcaca ttctggcgcg tcatgtggaa ggtgcttcgc
    13561 acatggcgga aggttatacc cgcgcaacgg cagggaatat cggcgtatgt ctggggactt
    13621 ccggtcctgc gggcacggac atgatcaccg cgctctattc cgcttctgct gattccattc
    13681 ctattctgtg cattaccggc caggctccgc gcgcccgtct gcataaagaa gatttccagg
    13741 ccgttgatat tgaagcaatt gctaaaccgg tcagcaaaat ggcggttaca gttcgtgaag
    13801 cggcgctggt gcctcgtgtg ctgcaacagg catttcacct gatgcgttct ggtcgtccgg
    13861 gtccggtact ggtggattta ccgttcgacg ttcaggttgc ggaaatcgag tttgatcctg
    13921 acatgtacga accgctgccg gtctacaaac ctgctgccag ccgtatgcag atcgaaaaag
    13981 ctgtagaaat gttaatccag gccgaacgtc cggtgattgt tgccgggggc ggggtaatta
    14041 atgctgacgc agctgcactg ttacaacagt ttgctgaact gaccagcgtt ccggtgatcc
    14101 caacgctgat gggctggggc tgtatcccgg acgatcatga actgatggcc gggatggtgg
    14161 gtctgcaaac cgcgcatcgt tacggtaatg caacgctgct ggcgtccgac atggtgtttg
    14221 gtatcggtaa ccgttttgct aaccgtcata ccggttcggt agagaaatac accgaagggc
    14281 gcaaaatcgt tcatatcgat attgagccga cgcaaattgg ccgcgtgctg tgtccggatc
    14341 tcggcattgt ctctgatgct aaagcggcgc tgacgctgct ggttgaagtg gcgcaggaga
    14401 tgcaaaaagc gggtcgtctg ccgtgtcgta aagaatgggt cgccgactgc cagcagcgca
    14461 aacgcacttt gctgcgcaaa acccatttcg acaatgtgcc ggtgaaaccg cagcgcgtgt
    14521 atgaagagat gaacaaagcc tttggtcgcg atgtttgtta tgtcaccacc attggtctgt
    14581 cacaaatcgc tgcggcacaa atgctgcatg tctttaaaga ccgccactgg atcaactgtg
    14641 ggcaggcagg cccgttgggc tggaccattc cggcggcgct gggcgtgtgt gccgctgatc
    14701 cagagcgcaa tgtggtggcg atttccggtg acttcgactt ccagttcctg attgaagaat
    14761 tagccgttgg cgcacagttc aacattccgt acatccatgt actggtcaat aacgcctatc
    14821 tcggtctgat tcgccagtcg cagcgcgcgt ttgatatgga ttactgcgta cagctcgcgt
    14881 tcgaaaatat taactccagc gaagtgaacg gttacggcgt cgaccacgta aaagtagcgg
    14941 aaggtttagg ttgtaaagcg attcgcgttt tcaaaccgga agatattgca ccggcctttg
    15001 aacaggcgaa agccttaatg gcgcaatatc gggtaccggt agtcgtggaa gttattctcg
    15061 agcgtgtgac caatatttcg atgggcagcg aactggataa cgtcatggaa tttgaagata
    15121 tcgcctataa cgcagtggac gcaccgactg aaacctgctt catgcactat gaataaggga
    15181 gataaataat gttacgtttc tctgctaatt tatcgatgtt atttggtgaa tatgattttc
    15241 tcgcccgttt tgagaaagct gcgcagtgtg gttttcgcgg cgttgaattt atgttccctt
    15301 atgactacga cattgaagaa ttaaaacagg tgctggcgag taataaactc gaacatacgc
    15361 tgcacaattt accggcaggt gactgggcgg cgggcgagcg gggtattgct tgtattcctg
    15421 gccgtgaaga agagtttcgg gatggcgtag cagcagcgat tcgttatgct cgtgcgctgg
    15481 gtaataaaaa aattaactgt ctggtcggta aaacgccgac tggtttcagc agtgaacaga
    15541 ttcacgcaac gcttgtagaa aacctgcgtt atgccgcgaa tatgctgatg aaagaagata
    15601 tcttattact gattgaacct atcaaccatt ttgatattcc tggtttccat ctcaccggaa
    15661 cccggcaggc actgaaactg attgatgatg ttggttgctg caatttgaaa attcagtatg
    15721 acatttatca tatgcagcgg atggaaggtg aattaaccaa cactatgact caatgggccg
    15781 ataaaattgg tcacctgcaa attgccgata atccgcatcg cggcgaaccg ggaaccggag
    15841 aaattaatta cgagtatctc tttacggtaa ttgaaaattc tgactacaac ggttgggttg
    15901 ggtgtgaata taaaccccaa accaccacgg aagccggttt acgctggatg gatccgtatc
    15961 gttaaaacgt aacgctattc agacaatgct tttttaggtc gctaagtcgg caggggatcg
    16021 tgttgtctga attcaggaaa agcgaaattt aaaagaggtt aattatgaaa ctgggattta
    16081 ttggcttagg cattatgggt acaccgatgg ccattaatct ggcgcgtgcc ggtcatcaac
    16141 tgcatgtcac aaccattggt ccggttgctg atgaattact gtcactgggt gccgtcagcg
    16201 ttgaaactgc gcgccaggta acggaagcat cggacatcat ttttattatg gtgccggata
    16261 cgccacaggt tgaagaagtt ctgtttggtg aaaatggttg taccaaagcc tcgttgaagg
    16321 gcaaaaccat tgttgatatg agctccattt ccccgatcga aactaaacgt ttcgctcgtc
    16381 aggtgaatga actgggcggt gattatctcg atgcgcccgt ctccggcggt gaaatcggcg
    16441 cgcgtgaagg gacgttgtcg attatggttg gcggtgacga agcggtattt gaacgtgtta
    16501 aaccgctgtt tgaactgctc ggtaaaaata tcaccctcgt gggcggtaac ggcgacggtc
    16561 aaacctgcaa agtagcaaat cagattatcg tagcgctcaa tattgaagcg gtttctgaag
    16621 ccctgctatt tgcttcaaaa gccggagcgg atctggtacg tgtgcgccag gcgctgatgg
    16681 gcggctttgc ttcctcacgt attctggaag ttcacggtga gcgcatgatt aaacgcacct
    16741 ttaatccagg ttttaaaatt gcgctgcacc agaaagatct caacctggca ctgcaaagtg
    16801 cgaaagcact ggcgctgaac ctgccaaaca ccgcgacctg ccaggaattg tttaatacct
    16861 gtgcggcaaa cggtggcagc cagttggatc actctgcgtt agtgcaggcg ctggaattaa
    16921 tggctaacca taaactggcc tgatacccgc aataaaaatg gccgatatca gaaaatgaat
    16981 cggccagcaa tattaaaa
//
LOCUS       DADXDL010000101        16756 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.101, whole genome shotgun sequence.
ACCESSION   DADXDL010000101 DADXDL010000000
VERSION     DADXDL010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16756)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16756)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16756
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.101"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..218
                     /locus_tag="IRB70_003972"
     CDS             <1..218
                     /locus_tag="IRB70_003972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633825.1"
                     /translation="IDPKINYNTDLNIEDSSSEEFLSDNTLEKDENSPDNCFEVVKYN
                     TYEAYNSEKQYFTREDYTYDYDLLNAI"
     gene            complement(325..701)
                     /gene="rnpB"
                     /locus_tag="IRB70_003973"
     ncRNA           complement(325..701)
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="IRB70_003973"
                     /product="RNase P RNA component class A"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00010"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00010"
     gene            complement(734..1879)
                     /gene="garK"
                     /locus_tag="IRB70_003974"
     CDS             complement(734..1879)
                     /gene="garK"
                     /locus_tag="IRB70_003974"
                     /EC_number="2.7.1.165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312029.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate 2-kinase"
                     /protein_id="HBC0633826.1"
                     /translation="MKIVIAPDSYKESLSASEVAQAIEKGFREIFPDAQYVSVPVADG
                     GEGTVEAMIAATQGSERHAWVTGPLGEKVNASWGISGDGKTAFIEMAAASGLELVPAE
                     KRDPLVTTSRGTGELILQALESGATNIIIGIGGSATNDGGAGMVQALGAKLCDANGNE
                     IGFGGGSLNTLNDIDISGLDPRLKDCVIRVACDVTNPLVGDNGASRIFGPQKGASEAM
                     IVELDNNLSHYADVIKKALHVDVKDVPGAGAAGGMGAALMAFLGAELKSGIEIVTTAL
                     NLEEHIHDCTLVITGEGRIDSQSIHGKVPIGVANVAKKYHKPVIGIAGSLTNDVGVVH
                     QHGIDAVFSVLTSIGTLDEAFRGAYDNIYRASRNIAATLAIGMRNAG"
     gene            complement(1976..2866)
                     /gene="garR"
                     /locus_tag="IRB70_003975"
     CDS             complement(1976..2866)
                     /gene="garR"
                     /locus_tag="IRB70_003975"
                     /EC_number="1.1.1.60"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312030.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxy-3-oxopropionate reductase"
                     /protein_id="HBC0633827.1"
                     /translation="MTMKVGFIGLGIMGKPMSKNLLKAGYSLVVADRNPEAIADVIAA
                     GAETASTAKAIAEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAPLA
                     SREISEALKAKGIDMLDAPVSGGEPKAIDGTLSVMVGGDKAIFDKYYDLMKAMAGSVV
                     HTGEIGAGNVTKLANQVIVALNIAAMSEALTLATKAGVNPDLVYQAIRGGLAGSTVLD
                     AKAPMVMDRNFKPGFRIDLHIKDLANALDTSHGVGAQLPLTAAVMEMMQALRADGLGT
                     ADHSALACYYEKLAKVEVTR"
     gene            complement(2896..3666)
                     /gene="garL"
                     /locus_tag="IRB70_003976"
     CDS             complement(2896..3666)
                     /gene="garL"
                     /locus_tag="IRB70_003976"
                     /EC_number="4.1.2.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydro-3-deoxyglucarate aldolase"
                     /protein_id="HBC0633828.1"
                     /translation="MNNDVFPNKFKAALAAKQVQIGCWSALSNPISTEVLGLAGFDWL
                     VLDGEHAPNDISTFIPQLMALKGSASAPVVRVPTNEPVIIKRLLDIGFYNFLIPFVET
                     KEEAEQAVASTRYPPEGIRGVSVSHRANMFGTVADYFAQSNKNITILVQIESQQGVDN
                     VDAIAATEGVDGIFVGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKPSGILAP
                     VEADARRYLEWGATFVAVGSDLGVFRSATQKLADTFKK"
     gene            complement(3682..5016)
                     /gene="garP"
                     /locus_tag="IRB70_003977"
     CDS             complement(3682..5016)
                     /gene="garP"
                     /locus_tag="IRB70_003977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate/glucarate/glycerate transporter
                     GarP"
                     /protein_id="HBC0633829.1"
                     /translation="MILDTVDVKKKGVHTRYLILLIIFIVTAVNYADRATLSIAGTEV
                     AKELQLSAVSMGYIFSAFGWAYLLMQIPGGWLLDKFGSKKVYTYSLFFWSLFTFLQGF
                     VDMFPLAWAGISMFFMRFMLGFSEAPSFPANARIVAAWFPTKERGTASAIFNSAQYFS
                     LALFSPLLGWLTFAWGWEHVFTVMGVIGFVLTALWIKLIHNPTDHPRMSAEELKFISE
                     NGAVVDMDHKKPGSAAASGPKLHYIKQLLSNRMMLGVFFGQYFINTITWFFLTWFPIY
                     LVQEKGMSILKVGLVASIPALCGFAGGVLGGVFSDYLIKRGLSLTLARKLPIVLGMLL
                     ASTIILCNYTNNTTLVVMLMALAFFGKGFGALGWPVISDTAPKEIVGLCGGVFNVFGN
                     VASIVTPLVIGYLVSELHSFNAALVFVGCSALMAMVCYLFVVGDIKRMELQK"
     gene            5391..6962
                     /gene="garD"
                     /locus_tag="IRB70_003978"
     CDS             5391..6962
                     /gene="garD"
                     /locus_tag="IRB70_003978"
                     /EC_number="4.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactarate dehydratase"
                     /protein_id="HBC0633830.1"
                     /translation="MANIEIRQETPTAFYIKVHDTDNVAIIVNDNGLKAGTRFPDGLE
                     LIEHIPHGHKVALLDIPANGEIIRYGEVIGYAVRAIPRGSWIDESMVVLPEAPPLHTL
                     PLATKVPEPLPPLEGYTFEGYRNADGSVGTKNLLGITTSVHCVAGVVDYVVKIIERDL
                     LPKYPNVDGVVGLNHLYGCGVAINAPAAVVPIRTIHNISLNPNFGGEVMVIGLGCEKL
                     QPERLLTGTDDVQAIPVESASIVSLQDEKHVGFQSMVEDILQVAERHLHKLNRRQRET
                     CPASELVVGMQCGGSDAFSGVTANPAVGYASDLLVRCGATVMFSEVTEVRDAIHLLTP
                     RAVNEEVGKRLLEEMEWYDNYLNMGKTDRSANPSPGNKKGGLANVVEKALGSIAKSGK
                     SAIVEVLSPGQRPTKRGLIYAATPASDFVCGTQQVASGITVQVFTTGRGTPYGLMAVP
                     VIKMATRTELANRWFDLMDINAGTIATGEETIEEVGWKLFHFILDVASGKKKTFSDQW
                     GLHNQLAVFNPAPVT"
     gene            7111..7446
                     /gene="prlF"
                     /locus_tag="IRB70_003979"
     CDS             7111..7446
                     /gene="prlF"
                     /locus_tag="IRB70_003979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PrlF"
                     /protein_id="HBC0633831.1"
                     /translation="MPANARSHAVLTTESKVTIRGQTTIPAPVREALKLKPGLDSIHY
                     EILPGGQVFMCRLGDEQEDHTMNAFLRFLDADIQNNPQKTRPFNIQQGKKLVAGMDVN
                     IDDEIGDDE"
     gene            7446..7910
                     /gene="yhaV"
                     /locus_tag="IRB70_003980"
     CDS             7446..7910
                     /gene="yhaV"
                     /locus_tag="IRB70_003980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ribonuclease
                     toxin YhaV"
                     /protein_id="HBC0633832.1"
                     /translation="MDFPQRVNGWALYAHPCFQETYDALVAEVETLKGKDPENYQRKA
                     ATKLLAVVHKVIEEHITVNPSSPAFRHGKSLGSGKNKDWSRVKFGAGRYRLFFRYSEK
                     EKVIILGWMNDENTLRTYGKKTDAYTVFSKMLKRGHPPADWETLTRETEETH"
     gene            complement(7965..8774)
                     /gene="agaR"
                     /locus_tag="IRB70_003981"
     CDS             complement(7965..8774)
                     /gene="agaR"
                     /locus_tag="IRB70_003981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aga operon transcriptional regulator AgaR"
                     /protein_id="HBC0633833.1"
                     /translation="MSNTDASGEKRVTGTSERREQIIQRLRQQGSVQVNDLSALYGVS
                     TVTIRNDLAFLEKQGIAVRAYGGALICDSTTPSVEPSVEDKSALNTAMKRSVAKAAVE
                     LIQPGHRVILDSGTTTFEIARLMRKHTDVIAMTNGMNVANALLEAEGVELLMTGGHLR
                     RQSQSFYGDQAEQSLQNYHFDMLFLGVDAIDLERGVSTHNEDEARLNRRMCEVAERII
                     VVTDSSKFNRSSLHKIIDTQRIDMIIVDEGIPADSLEGLRKAGVEVILVGE"
     gene            9023..10303
                     /gene="kbaZ"
                     /locus_tag="IRB70_003982"
     CDS             9023..10303
                     /gene="kbaZ"
                     /locus_tag="IRB70_003982"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaZ"
                     /protein_id="HBC0633834.1"
                     /translation="MKHLTEMVRQHKEGKTNGIYAVCSAHPLVLEAAIRYASANQTPL
                     LIEATSNQVDQFGGYTGMTPADFRGFVCQLADSLNFPQDALILGGDHLGPNRWQNLPA
                     AQAMANADDLIKSYVAAGFKKIHLDCSMSCQDDPIPLTDDIVAERAARLAKVAEETCR
                     EHFGAADLEYVIGTEVPVPGGAHETLSELAVTTPDAARATLEAHRHAFEKQGLNAIWP
                     RIIALVVQPGVEFDHTNVIDYQPAKATALSQMVENYETLIFEAHSTDYQTPQSLRQLV
                     IDHFAILKVGPALTFALREALFSLAAIEEELVPAKACSGLRQVLENVMLDRPEYWQSH
                     YHGDGNARRLARGYSYSDRVRYYWPDSQIDDAFAHLVRNLADSPIPLPLISQYLPLQY
                     VKVRSGELQPTPRELIINHIQDILAQYHTACEGQ"
     gene            10326..10799
                     /gene="agaV"
                     /locus_tag="IRB70_003983"
     CDS             10326..10799
                     /gene="agaV"
                     /locus_tag="IRB70_003983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312038.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS N-acetylgalactosamine transporter subunit
                     IIB"
                     /protein_id="HBC0633835.1"
                     /translation="MPNIVLSRIDERLIHGQVGVQWVGFAGANLVLVANDEVAEDPVQ
                     QNLMEMVLAEGIAVRFWTLQKVIDNIHRAADRQKILLVCKTPADFLTLVKGGVPVNRI
                     NVGNMHYANGKQQIAKTVSVDAGDIAAFNDLKAAGVECFVQGVPTEPAVDLFKLL"
     gene            10810..11589
                     /locus_tag="IRB70_003984"
     CDS             10810..11589
                     /locus_tag="IRB70_003984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS
                     mannose/fructose/sorbose/N-acetylgalactosamine transporter
                     subunit IIC"
                     /protein_id="HBC0633836.1"
                     /translation="MEISLLQAFALGIIAFIAGLDMFNGLTHMHRPVVLGPLVGLVLG
                     DLHTGILTGGTLELVWMGLAPLAGAQPPNVIIGTIVGTAFAITTGVKPDVAVGVAVPF
                     AVAVQMGITFLFSVMSGVMSRCDRMAENADTRGIERVNYLALLALGTFYFLCAFLPIY
                     FGAEHAKTIIDVLPQRLIDGLGVAGGIMPAIGFAVLLKIMMKNVYIPYFILGFVAAAW
                     LKLPVLAIAAAALAMALIDLLRKSPEPTQPAAQKEEFEDGI"
     gene            11579..12457
                     /locus_tag="IRB70_003985"
     CDS             11579..12457
                     /locus_tag="IRB70_003985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019079236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBC0633837.1"
                     /translation="MASNQTTLPNVSENEETLLTGVNENVYEDQSIGAELTKKDINRV
                     AWRSMLLQASFNYERMQASGWLYGLLPALKKIHTNKRDLARAMKGHMGFFNTHPFLVT
                     FVIGIILAMERSKQDVNSIQSTKIAVGAPLGGIGDAMFWLTLLPICGGIGASLALQGS
                     ILGAVVFIVLFNVVHLGLRFGLAHYAYRMGVAAIPLIKANTKKVGHAASIVGMTVIGA
                     LVATYVRLSTTLEITAGDAVVKLQADVIDKLMPAFLPLVYTLTMFWLVRRGWSPLRLI
                     AITVVLGIVGKFCHFL"
     gene            12475..12909
                     /locus_tag="IRB70_003986"
     CDS             12475..12909
                     /locus_tag="IRB70_003986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBC0633838.1"
                     /translation="MLSIILTGHGGFASGMEKAMKQILGEQSQFIAIDFPETSSTALL
                     TSQLEEAIAQLDCEDGIVFLTDLLGGTPFRVASTLAMQKPGCEVITGTNLQLLLEMVL
                     EREGLSGEEFRVQALECGHRGLTSLVDELGRCHEECPVEEGI"
     gene            12906..14039
                     /gene="nagA"
                     /locus_tag="IRB70_003987"
     CDS             12906..14039
                     /gene="nagA"
                     /locus_tag="IRB70_003987"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312042.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBC0633839.1"
                     /translation="MTHVLRARRLLTEEGWLDDHQLRIADGVIAAIEPIPVGVTERDA
                     ELLCPAYIDTHVHGGAGVDVMDDAPDALDKLAMHKAREGVGSWLPTTVTAPLNTIHAA
                     LKRIALRCQRGGPGAQVLGSYLEGPYFTPQNKGAHPPELFRELEIAELDQLIAVSQHT
                     LRVVALAPEKEGALQAIRHLKQQNVRVMLGHSAATWQQTRAAFDAGADGLVHCYNGMT
                     GLHHREPGMVGAGLTDKRAWLELIADGHHVHPAAMSLCCCCAKERIVLITDAMQAAGM
                     PDGRYTLCGEEVQMHDGVVRTASGGLAGSTLSVDAAVRNMVELTGVTPAEAIHMASLH
                     PARMLGVDGVLGSLKPGKRASVVALDSGLHVQQIWIQGQLASF"
     gene            14390..15544
                     /locus_tag="IRB70_003988"
     CDS             14390..15544
                     /locus_tag="IRB70_003988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AgaS family sugar isomerase"
                     /protein_id="HBC0633840.1"
                     /translation="MPENYTPAAAATGTWTEEEIRHQPRAWIRSLTNIDALRSALNNF
                     LEPLLRKENLRVILTGAGTSAFIGDIIAPWLASHTGKNFSAVPTTDLVTNPMDYLNPA
                     HPLLLISFGRSGNSPESVAAVELANQFVPECYHLPITCNEAGALYQNAINSDNAFALL
                     MPAETHDRGFAMTSSITTMMASCLAVFAPETINSQTFRDVADRCQEILTSLGDFSEGV
                     FGYAPWKRIVYLGSGGLQGAARESALKVLELTAGKLAAFYDSPTGFRHGPKSLVDNET
                     LVVVFVSSHPYTRQYDLDLLAELRRDNQALRVIAIAAESNDVITAGPHIILPPSRHFI
                     DVEQAFCFLMYAQTFALMQSLHMGNTPDTPSASGTVNRVVQGVIIHPWQA"
     gene            15557..16417
                     /gene="kbaY"
                     /locus_tag="IRB70_003989"
     CDS             15557..16417
                     /gene="kbaY"
                     /locus_tag="IRB70_003989"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase subunit KbaY"
                     /protein_id="HBC0633841.1"
                     /translation="MSIISTKYLLQDAQANGYAVPAFNIHNAETIQAILEVCSEMRSP
                     VILAGTPGTFKHIALEEIYALCSAYSTTYNMPLALHLDHHESLDDIRRKVHAGVRSAM
                     IDGSHFPFAENVKLVKSVVDFCHSQDCSVEAELGRLGGVEDDMSVDAESAFLTDPQEA
                     KRFVELTGVDSLAVAIGTAHGLYSKTPKIDFQRLAEIREVVDVPLVLHGASDVPDEFV
                     RRTIELGVTKVNVATELKIAFAGAVKAWFAENPQGNDPRYYMRVGMDAMKEVVRNKIN
                     VCGSANRISA"
     gene            16584..>16756
                     /locus_tag="IRB70_003990"
     CDS             16584..>16756
                     /locus_tag="IRB70_003990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBC0633842.1"
                     /translation="MSSPNILLTRIDNRLVHGQVGVTWTSTIGANLLVVVDDVVANDD
                     IQQKLMGITAETYG"
BASE COUNT         4076 a         4414 c         4272 g         3994 t
ORIGIN      
        1 ttatcgatcc aaaaattaat tacaatacag atttaaacat agaggattct agctcagagg
       61 aattcctttc agataataca ctagagaaag acgaaaattc tcctgacaat tgctttgagg
      121 tcgtaaaata taacacatat gaagcttata actcagagaa gcaatatttt accagagagg
      181 actatacgta tgattacgac cttttaaatg caatatagac ttaataattt cttacaaagt
      241 ctattattaa taccgtagat atttattcat cttacactat gctccaaaag caaaaacccg
      301 ccgaagcggg tttttacgta aaacaggtga aactgaccga taagccgggt tctgtcgtgg
      361 acagtcattc atctaggcca gcaatcgctc actggctcaa gcagcctacc cgggttcagt
      421 acgggccgta ccttatgaac ccctatttgg ccttgctccg ggtggagttt accgtgccac
      481 ggactgttac cagccgcgcg gtgcgctctt accgcaccct ttcaccctta cctgatcccg
      541 cttgcgcggg ccatcggcgg tttgctctct gttgcactgg tcgtgggttt cccccccagg
      601 cgttacctgg caccctgccc tatggagccc ggactttcct cccctccgcc cgtctccccc
      661 gaagaggacg acgacgaagc ggcgactgtc tggtcagctt cggcgcgcag tatagagggt
      721 ttgcgcgccc ttgtcacccc gcgttgcgca ttccaatcgc cagtgtcgcg gcgatattac
      781 gtgaagcacg gtaaatattg tcataagccc cgcggaatgc ttcgtccaac gtaccaatac
      841 tggtcaatac gctgaagacc gcatcaatgc catgctgatg tacaacgcca acatcattgg
      901 tcaggctacc cgcaatgcca atcaccggtt tatggtactt tttcgccacg tttgcgacgc
      961 caatcggaac cttgccgtgt atactctggc tgtcaatacg cccttcaccg gtgatcacca
     1021 gcgtacaatc gtgaatatgt tcctccagat tcagcgccgt agtgacgatt tcaataccac
     1081 ttttcagttc cgcaccaaga aacgccatta gcgccgcgcc cataccaccc gcagctcctg
     1141 cgccggggac atctttcaca tcaacatgca gcgctttttt aatgacatcg gcatagtgag
     1201 agaggttatt gtccagctca acaatcatcg cttcactggc tcccttttgt gggccaaaga
     1261 tgcgcgatgc gccgttatcg cccaccagcg gattggtgac atcacaagcg acgcgaatga
     1321 cgcaatcttt taagcgcgga tcgaggccgg aaatatcaat atcattcaga gtattaagac
     1381 taccgccgcc aaaaccaatt tcattgccgt tggcgtcgca taatttcgcc cccagcgcct
     1441 gtaccatgcc tgcaccgcca tcatttgtag cgctaccgcc aatgccgata ataatgtttg
     1501 tcgcgccgct ctccagcgcc tgcagaatta actcgcctgt gccgcgtgaa gtggtcacga
     1561 gtggatcacg tttttccgca ggtaccagct ccagcccact ggccgccgcc atttcaataa
     1621 acgcggtttt gccatcgccg gagatccccc aactggcatt caccttctcg cccagcggcc
     1681 ctgtaaccca ggcgtgacgt tcggaaccct gggtggctgc aatcatcgct tccaccgttc
     1741 cttcgccacc gtcggcaaca ggaacagaaa cgtactgtgc atcaggaaaa atttcccgaa
     1801 atcctttttc tatcgcctgc gcaacctcgc tggcagataa actttcttta taagagtctg
     1861 gggcgattac gattttcata cctatgcctg ttaccacatg acgccggagg gcgtttctct
     1921 tattcggcct ggattccagg cccggattgc aatacgccat ccgggcacga cgtcattaac
     1981 gagtaacttc gactttcgcc agtttttcgt agtagcacgc cagggcgcta tgatctgccg
     2041 ttcctaaacc atctgctcgc agtgcctgca tcatctccat aaccgcagct gtgagcggca
     2101 gttgcgcgcc gacgccgtgg gaagtatcca gcgcatttgc cagatcctta atatgcagat
     2161 caatacggaa gcccggcttg aagttgcggt ccatcaccat cggcgctttg gcatccagca
     2221 cggtactgcc cgccagtcca ccgcgaattg cctgatacac caaatccggg ttaacgcccg
     2281 ctttggttgc cagcgttaac gcttctgaca tcgcggcaat attcagcgcc acaatgacct
     2341 gattcgccag tttggtaacg ttacctgcac caatttcccc ggtatgcacc acggaacccg
     2401 ccattgcttt catcaaatca tagtatttgt cgaaaatagc cttgtcgccg cccaccatca
     2461 ctgacagcgt accgtcgata gctttcggtt caccgccgct caccggagca tccagcatat
     2521 caatgccttt cgctttcagc gcttcgctga tttcacggct tgccagcggt gcgatagaac
     2581 tcatatcgat caataccgta ccaggcttcg cgccttcaat aatcccattc tcacccagcg
     2641 ccacctcttt cacatgaggg gagtttggca gcatggttat gatgacgtcg cactgttcag
     2701 cgatcgcttt agccgtagag gctgtttctg cacctgcagc aatcacgtca gcaatagctt
     2761 ctgggttacg gtcagcaacc accagcgagt aacctgcttt cagaaggttt ttactcattg
     2821 gtttacccat aatccccagg ccaataaaac caactttcat agtcatatca atcatctctc
     2881 ttgttgcggt ggtggttatt ttttaaaggt atcagccagt ttctgagtgg cagagcggaa
     2941 gacgccgaga tcgctgccga cagccacaaa cgtcgccccc cattccagat aacgacgcgc
     3001 atcggcttcg accggtgcga ggataccgct gggtttgccg tgcgcactgg cacggttaaa
     3061 aatatgctga attgcttttt gtacatccgg gtgcgaggca ttgccgagat ggcctaatgc
     3121 cgcagccaga tcgctggggc cgacgaagat accgtctacg ccttcggtag cggcaatggc
     3181 atcgacgtta tctacgccct gctgactttc tatctggacc agaatggtga tgttcttgtt
     3241 cgactgagcg aaataatccg ccacggtgcc aaacatattg gcgcggtgag aaacggagac
     3301 gccgcgaatg ccttccggtg ggtaacgggt tgatgccacc gcctgctctg cttcctcttt
     3361 tgtttctaca aaaggaatca ggaagttata gaaaccgata tccagaagac gcttaataat
     3421 taccggctcg ttggtcggca ctcgtactac tggcgcgctg gcgctgcctt tcagggccat
     3481 taactgcgga ataaacgtgg agatatcgtt tggcgcatgt tcgccatcca gcaccagcca
     3541 gtcaaaccca gccaaaccaa gaacttcagt gctaatcggg ttagagagtg ctgaccagca
     3601 accaatttgt acctgtttcg cagccagtgc ggctttgaat ttattcggga aaacatcgtt
     3661 attcatcgct tatacctttg cttatttctg caattccata cgtttaatgt cgccgactac
     3721 gaagaggtag cagaccatcg ccatcagcgc tgaacatccc acgaaaacca gtgctgcatt
     3781 gaaggagtgc aattcactta ccaggtagcc aatcaccagt ggagtgacaa tggaggcaac
     3841 attgccaaag acgttaaaga cgccgccgca gagaccaaca atctctttcg gcgcggtgtc
     3901 agaaatcact ggccagccca gcgcaccaaa tcctttgcca aagaaagcca gcgccatcag
     3961 catgaccacc agcgtggtgt tgttggtgta gttacataag ataatggtgg aagccagcaa
     4021 cattcccagc acaatcggta gcttacgtgc cagggtcagg gacaaaccgc gtttgatcag
     4081 ataatccgag aagacacctc ccagtacgcc gcccgcaaag ccacacagtg ccggaatcga
     4141 ggcgaccaga cccactttca gaatcgacat gcctttttcc tgaaccagat aaattgggaa
     4201 ccaggtgagg aagaaccagg tgatggtgtt gataaaatat tgtccgaaaa atacgcccag
     4261 catcatgcgg ttagagagca attgcttgat gtaatgcagt ttgggaccgc ttgctgccgc
     4321 actgcccggc tttttgtggt ccatatcgac caccgcgcca ttttctgaga taaacttcag
     4381 ctcttccgca gacatacgtg ggtgatctgt cgggttatga atcaacttga tccacagcgc
     4441 cgtcagcaca aaaccaatca cccccataac ggtgaagacg tgctcccagc cccaggcgaa
     4501 agtcagccag ccaagcagcg gcgaaaagag cgccagcgag aaatattgcg ccgagttaaa
     4561 gatggcggag gcagtaccac gttctttcgt tgggaaccag gcggcgacaa tacgggcgtt
     4621 cgccggaaat gatggcgctt ccgagaaccc cagcataaag cgcataaaga acatggagat
     4681 ccctgcccag gccagcggga acatatcaac aaagccttgc aggaaggtga acagcgacca
     4741 gaaaaagagg ctgtaggtgt aaactttttt cgagccaaac ttatcaagca gccagccgcc
     4801 gggaatttgc atcagcaggt aggcccagcc aaaagcggag aagatgtaac ccatcgaaac
     4861 cgcacttaac tgcaactctt ttgccacttc ggtaccagca atagacagcg ttgcacgatc
     4921 ggcgtagtta acggcggtaa caataaaaat aatcagtaat attaaatagc gggtatgcac
     4981 gcctttcttt tttacgtcaa cggtgtccag aatcatttta tttacctcgg gtacttatgc
     5041 tgatttttat tattatgggg aaggtgttat ttatgagttt tatttatgcc gttacggcaa
     5101 tgaactcggg aattagtata agcagcgcga gaataataat cattgtgcaa atgctaattt
     5161 aattaatact atttaaatat tattttgagc atatgcacat aaggttgcgc gctaaagcac
     5221 agatttgcgc tttaccttgc cggacggcac tgcaatccct gaaatgattg acattgatca
     5281 catttctgcg tttaaactcc tgacattctt atttcaccca atgaagtcat ttatttttaa
     5341 atgagaccag gtcctcattt taataacccc tggctggaga atattgcaca atggccaaca
     5401 tcgaaatcag acaagaaacg ccaactgcgt tttatataaa agttcacgac acagataatg
     5461 tggcaattat tgttaatgat aatggcctga aagcaggaac gcgttttccg gatgggctgg
     5521 aattaattga acatattccc catgggcata aagtcgcatt gctggacatt ccagctaatg
     5581 gtgaaattat tcgttatggc gaagtgattg gttacgccgt gcgcgcaatc ccacgcggaa
     5641 gctggatcga cgaatcaatg gttgtactac cggaagcgcc gccgttacac acgctgccac
     5701 tggcaaccaa agtcccggaa cccttaccgc cgctggaagg atacaccttt gagggctatc
     5761 gcaatgccga tggcagcgtg ggcactaaaa acctgctcgg catcaccacc agcgtccact
     5821 gtgtagcagg cgtggtggac tatgtagtaa aaatcattga acgcgatctg ctaccgaaat
     5881 acccgaacgt cgatggcgtg gtggggctga atcatttgta cggctgtggc gtggcgatta
     5941 acgcaccggc ggcagttgtg cctattcgta ccatccacaa tatttcgctg aaccctaact
     6001 ttggcggcga agtaatggtg attggtctgg gttgtgaaaa gttgcagcct gagcgcctgc
     6061 tgactggaac ggatgatgtg caagctattc cagtagaaag cgccagcatt gtcagtttgc
     6121 aggatgaaaa gcatgtcggc tttcagtcca tggtcgagga tattttgcag gtcgccgaac
     6181 gccatttgca caaactgaat cgacggcagc gagaaacctg tccggcttca gaactggttg
     6241 tcggcatgca gtgcggtggc agcgatgcgt tttctggcgt aacggcaaac ccggcggttg
     6301 ggtatgcgtc tgatctactg gtgcgctgcg gcgcaacggt gatgttttca gaagtcacgg
     6361 aagtgcgtga cgcgatccat ctgctgacac cacgcgcagt gaacgaagag gtcggcaaac
     6421 ggctgctgga ggagatggag tggtacgata actatctcaa tatgggaaaa accgaccgca
     6481 gcgccaaccc ttcgccgggc aacaagaaag gcggtctggc aaatgtggtg gagaaggcac
     6541 tcggctccat tgcgaaatcg ggtaaaagtg cgattgttga agtgctgtcg cctggtcaac
     6601 gcccgactaa acgcggatta atttacgccg cgacgccagc cagcgatttt gtctgtggca
     6661 cgcaacaggt ggcttcgggt atcaccgtgc aagtgtttac gaccggtcgt ggtacgccgt
     6721 acggcctgat ggcggtaccc gtcattaaaa tggcaacccg caccgagctg gcgaaccgct
     6781 ggtttgattt aatggatatt aatgcgggca ccatcgctac cggcgaagaa actattgaag
     6841 aggtgggctg gaagttgttc cactttattc tcgacgtcgc cagcgggaag aagaaaacct
     6901 tctcagatca atggggactg cataaccagc tggcggtgtt taacccagca ccggtgacct
     6961 gatttctttt ggaacgtccc tcgcaaaaca tggccttagt gccatgtttt tattgtttaa
     7021 agcccccacg accattaata atgcatttgc attaccttag ttcaagctta taatttgagc
     7081 agaaaacagg ctgtaaaagg acagtgaatc atgcccgcta atgctcgctc tcacgctgta
     7141 ctgaccactg aatcaaaggt cacgatacgc ggacaaacaa ctatccccgc gccagtgcgt
     7201 gaggccttaa aactgaagcc aggcctggac agcattcatt acgaaattct gcctggtggg
     7261 caagtattta tgtgccgact gggagatgaa caggaggatc atactatgaa tgcatttttg
     7321 cgttttctgg atgcagatat ccagaacaac ccgcaaaaaa ctcgtccatt caacattcaa
     7381 caaggaaaga aacttgtcgc tggcatggac gtcaacattg atgatgagat tggcgacgac
     7441 gaataatgga ttttccacaa agggttaatg gttgggcgct atatgctcat ccctgttttc
     7501 aggaaaccta cgacgcttta gttgccgaag tcgagacatt aaagggaaaa gatcctgaaa
     7561 attatcagag aaaagccgcc acaaagttat tggcggtagt ccataaagtg attgaggagc
     7621 atatcacggt caatccatca tcaccggcat tccgtcatgg caagtcgtta ggctctggga
     7681 aaaataaaga ctggtcacgg gtaaaatttg gtgctggtcg ttatcgtctc ttctttcgtt
     7741 acagcgaaaa agagaaagtc atcattctgg gatggatgaa cgatgaaaac acgctgcgca
     7801 cctacggtaa aaaaacagat gcctataccg tattcagcaa aatgttaaaa agaggacatc
     7861 ctcctgccga ctgggaaacc ctcacccgag agacagaaga aacccattga tggtattcac
     7921 aatgcccgcc gaacgcattc gtgttgacca gcgggcaccc tttctcactc cccgaccaga
     7981 atcacttcaa ccccagcctt tcgcagtcct tccagactat ccgcaggaat gccttcatca
     8041 acaatgatca tgtcgatacg ttgagtatca atgatcttat gtaaactgga acggttgaac
     8101 ttactggaat cggtgaccac gatgatccgt tccgcaactt cgcacatccg acggtttaaa
     8161 cgggcttcat cttcattatg cgtgctgacg ccgcgctcca gatcgatcgc atctacacca
     8221 agaaacagca tatcgaagtg gtaattttgc agcgattgct cagcctgatc accgtaaaaa
     8281 gattgcgact gacggcgcaa atgccccccg gtcatcagca gctcaacgcc ttccgcttcc
     8341 agcaacgcat tagccacgtt cataccgttg gtcatcgcaa ttacgtcggt gtgcttgcgc
     8401 atcagacgag caatctcaaa agtggtggtc ccggagtcga ggatcacccg atgaccaggc
     8461 tgaatcaact caacggcagc tttcgcaacg ctgcgtttca ttgcggtgtt cagcgcgctt
     8521 ttatcttcca ctgatggctc gactgacggc gtcgtgctat cgcagatcaa cgcgccgcca
     8581 taggcacgca cagcgatccc ctgcttttcc agaaacgcca gatcgttgcg gatcgtcaca
     8641 gtagatacac catacaacgc cgatagatca ttaacttgca cactcccttg ctggcgcagg
     8701 cgttgaatga tctgctctcg tcgctcactg gtgcctgtca ctcgcttctc gcctgaagcg
     8761 tcggtattac tcatagtaag tcctttcgta aaactttcgt ttcatttcgt tttgcctatt
     8821 aacgcctttc tattaagcaa atgcaagccc accttaccca ttggcgcaag ctactctcgt
     8881 ttcagtggct ttcattatgt ttcttttgtg aatcagatca gaaaactatt atctttcgtt
     8941 ttatttttat ctcaccatgg cgcagtatca actgaaacaa aacgaaagat taatatcgca
     9001 gtaatctgaa ctggagagga aagtgaaaca tctgacagaa atggtgagac agcacaaaga
     9061 gggcaaaaca aatgggattt atgccgtttg ttccgcacat ccgctggtgc tggaagctgc
     9121 aatccgctac gccagtgcaa accaaacgcc gttactgatt gaagcaacct ccaatcaggt
     9181 ggaccagttc ggcggttata ccggaatgac gcccgccgat tttcgcggct ttgtttgtca
     9241 gctcgccgac tcgttgaatt tcccacagga tgcgttgatt ctgggtggcg accatctggg
     9301 gccaaaccgc tggcaaaacc tgcctgccgc tcaggcaatg gccaatgccg atgatttgat
     9361 taaaagctac gtggcggcag gattcaaaaa aattcacctt gattgcagca tgtcctgtca
     9421 ggacgatccg attcccttaa ctgatgacat cgtggccgaa cgcgccgctc gtctggcgaa
     9481 agtggcggaa gaaacctgcc gtgaacattt tggcgcggcc gatctggagt atgtcattgg
     9541 taccgaagta ccggtacctg gcggcgcgca tgaaacctta agcgagctgg cggtcaccac
     9601 gccggatgcc gcccgcgcca cactggaagc ccatcgccac gcctttgaaa agcagggcct
     9661 gaatgccatc tggccacgca ttattgccct ggtggttcaa cccggcgtcg aattcgatca
     9721 caccaacgtt attgattatc agccagctaa agcgaccgca ttaagccaga tggtcgaaaa
     9781 ctacgaaacg ctgattttcg aagcgcactc taccgattac caaacgccgc aatcgttgcg
     9841 ccagctggtg attgaccact ttgccattct gaaagttggc ccggcgctga ccttcgccct
     9901 gcgtgaagct ctgttctctc tggcggcgat tgaagaagaa ctggtgccag caaaagcctg
     9961 ttctggtctg cgtcaggtgc tggaaaacgt gatgctcgac cgcccggaat actggcaaag
    10021 ccactaccac ggtgacggca acgcgcgtcg tctggcgcgt ggttatagct actcggatcg
    10081 cgtgcgctat tactggccgg acagccagat tgatgacgct ttcgctcatc tggttcgtaa
    10141 tctggcggat tcaccaattc cgctaccgct catcagccag tatttgccgc tgcaatacgt
    10201 gaaagttcgc tccggcgagc tgcagccaac accacgggaa ctcattatca accatattca
    10261 ggacatcctg gcgcagtacc acacagcctg tgaaggccaa taagcaaaac aaagaggaac
    10321 acgctatgcc aaatattgtt ttaagccgga ttgatgagcg tttgattcac ggtcaggtcg
    10381 gcgttcagtg ggtcggattt gcgggggcaa atctggtgct ggtagccaac gatgaggttg
    10441 ccgaagatcc ggtacaacaa aacctgatgg aaatggtact ggcagaaggg atcgccgtac
    10501 gtttctggac gctgcaaaaa gtcatcgaca acattcatcg cgccgccgat cgacagaaaa
    10561 tcctgctggt ttgtaaaaca cctgccgatt tcctgacgct ggtgaaaggt ggcgttccgg
    10621 tgaatcgcat taacgttggc aatatgcact acgccaatgg caagcaacaa atcgccaaaa
    10681 cggtttctgt ggatgcgggt gatatcgcag catttaacga cctgaaagcc gctggggtgg
    10741 aatgcttcgt tcagggcgtc ccgacagagc ctgctgtgga cctctttaaa ttactttgag
    10801 ggattcatca tggaaatcag tctgttgcag gcattcgcgt tgggcattat cgcctttatc
    10861 gctggcctgg atatgtttaa cggcctaacc catatgcacc gcccggtggt cctcggcccg
    10921 ttggtcgggc tggtacttgg cgatctgcat accggtattt taaccggcgg tacgctggaa
    10981 ctggtgtgga tggggctggc cccgctggcg ggcgcacagc cgcctaacgt gattatcggt
    11041 actatcgtcg gcacggcgtt tgccattact actggcgtga aacccgatgt cgcggtcggt
    11101 gtcgccgtac ctttcgctgt cgcagtacag atggggatta ccttcctgtt ctcggtgatg
    11161 tccggcgtga tgtcccgatg cgaccggatg gcggagaacg ccgatactcg cggcattgaa
    11221 cgcgtgaact atctggcact gctggcactc ggcactttct attttctctg cgctttcctg
    11281 cctatctact tcggcgcgga acatgcaaaa accatcattg atgtcctgcc gcaacgatta
    11341 atcgacggcc tcggcgtcgc gggcggcatc atgccagcaa tcggttttgc cgtgttgctg
    11401 aaaatcatga tgaaaaacgt ctacatcccc tacttcatcc tgggctttgt tgccgcagcc
    11461 tggctcaagt taccggtgtt ggctattgct gccgctgcgc tggcgatggc gctgatcgac
    11521 ctgctgcgta aatctcctga accgactcaa cctgcggcac agaaagagga atttgaagat
    11581 ggcatctaat caaaccaccc tgccgaacgt cagtgaaaac gaagaaacac tgctgacagg
    11641 cgtcaatgaa aacgtgtatg aagatcagag cattggcgca gagctgacga aaaaagatat
    11701 caaccgcgtc gcctggcgtt ccatgctgtt acaggcttct ttcaactacg aacgtatgca
    11761 ggcttccggc tggctgtacg gcctgctgcc agcactgaaa aagatccaca ctaataaacg
    11821 cgacctggcg cgcgctatga aggggcatat gggtttcttc aatacccatc cgtttctggt
    11881 gacgtttgtt atcggcatta tccttgcgat ggagcgttct aagcaggacg ttaacagtat
    11941 tcagagcacc aaaattgccg tcggtgcgcc gctcggcggg attggcgatg cgatgttctg
    12001 gctaacgcta ctgccgattt gtggcgggat aggtgcaagc ctcgcgctac aaggctctat
    12061 tcttggcgct gtcgtcttta ttgtgctgtt caacgtggtg cacctggggc tgcgttttgg
    12121 tctggcgcat tatgcttacc gcatgggcgt ggcggcgatt ccactcatta aagcaaatac
    12181 caaaaaagtc ggccatgcgg catctatcgt tgggatgacg gtaatcggcg cgctggtggc
    12241 aacctatgtt cgtttaagca ccacgctgga aatcaccgcg ggcgacgcag tggttaagtt
    12301 acaggctgat gttatcgaca aactgatgcc agccttctta ccgctggtct acaccctgac
    12361 catgttctgg ctggtacgcc gcggctggag tccgctgcgc ctgattgcga ttaccgtggt
    12421 tctcggcatc gtcggtaaat tctgccattt cctttaaata caatgaggta ttagatgtta
    12481 agtattattt tgacagggca tggcggattt gccagcggca tggaaaaagc aatgaagcaa
    12541 attctcggtg agcaatcgca gtttatcgcc atcgattttc cggaaacctc aagcaccgcg
    12601 ctgcttacat cgcagcttga agaggccatc gcccaactgg attgtgaaga cggcattgtt
    12661 tttctgacgg atttgctggg cggcacgccg tttcgcgtag cttcaacgct ggcgatgcaa
    12721 aaaccgggct gtgaagtgat caccggcacc aatttgcaac tgctactgga aatggtgctg
    12781 gagcgcgaag ggttaagcgg tgaagagttc cgtgtgcagg cgctggagtg tggacatcgt
    12841 gggctgacca gtctggtgga cgagttaggc cgctgccatg aagaatgtcc ggtcgaggaa
    12901 ggaatatgac acacgttctg cgcgccagaa ggctgctgac tgaagaggga tggctcgatg
    12961 accatcagtt gcgtattgct gacggtgtaa tcgcagcaat cgaaccgatt ccagtgggcg
    13021 tgactgaacg cgatgcggaa ctgctctgtc ccgcttacat cgacacccat gtacacggtg
    13081 gtgcgggcgt tgatgtaatg gatgacgcgc cggatgcgct cgacaagctg gcaatgcaca
    13141 aggcacgaga aggtgtcggc agttggttac cgaccaccgt aaccgcgccg cttaatacca
    13201 ttcatgcggc gctgaaacgt attgctctac gctgccagcg tggcggacct ggtgcgcaag
    13261 tgctggggag ttatctcgaa ggaccgtact tcacgccgca gaataaaggc gcgcatccgc
    13321 cggagctgtt tcgcgagctg gaaattgccg agctggatca attgattgcc gtttctcagc
    13381 acaccttgcg cgtggtagcg ctggcaccag aaaaagaagg ggcattgcag gccatccgcc
    13441 atcttaaaca gcaaaacgta cgggtgatgc tggggcatag cgcggcgacc tggcaacaaa
    13501 cccgtgccgc gtttgacgct ggtgccgacg gcctggtgca ttgctataac gggatgacag
    13561 gtttacatca ccgcgaaccg ggaatggttg gcgcgggatt aacggacaag cgcgcctggc
    13621 tggaactgat agccgatggt catcatgtac atccggcggc gatgtcgctg tgttgttgct
    13681 gtgcgaaaga gagaatcgtg ctgatcaccg acgcgatgca ggcagccggg atgccggatg
    13741 gtcgctatac gttatgtggt gaagaagtgc agatgcacga tggcgttgtc cgtaccgcgt
    13801 ccggtgggct ggcgggcagt acgctgtctg tcgatgcggc agtgcgcaac atggtcgagt
    13861 tgacgggcgt aacgcctgcg gaagccatcc atatggcatc gctgcatccg gcgcgtatgc
    13921 tgggtgttga tggtgttctg ggatcgctta aaccgggcaa acgcgccagc gtcgttgcgc
    13981 tggatagcgg gctgcatgtg caacaaatct ggattcaggg tcaattagct tcgttttgat
    14041 ggtttgctcc tttattgggc cttcacttcc cccgtaaggc ctttcttttt ctttcttttt
    14101 gatctgtgca gcggtgtcgg atgcgacgct gacgcgtctt cttcgaccta cggtacgccg
    14161 catccggcaa tcggtgaaca tagcgacgtt atcacgcaat cctttaatct tcccttgtct
    14221 tttctttcaa tgatcacaaa tttcgtttta tttctttttt ctccattgaa ctttcagttt
    14281 cttttctata gattttaatc aacgaaagac atcaccaagt gaaatgaaac gaaaggtaag
    14341 cgaaagcgac aacgcccgac gccaagttca tcagactaag gattgagtta tgccagaaaa
    14401 ttacacccct gctgccgctg caaccggtac atggactgaa gaagagatcc gccatcagcc
    14461 tcgcgcatgg atccgttcac tcaccaacat cgacgcgcta cgttccgcgc tcaataactt
    14521 ccttgaaccg ttactgcgca aagagaatct gcgggtaatc ctgaccggag ccggaacctc
    14581 ggcatttatc ggtgatatca tcgcgccgtg gctcgccagc cataccggta aaaacttcag
    14641 cgccgtaccg accaccgatc tggtcactaa tccgatggac tacctgaatc cagctcatcc
    14701 gctactgttg atctccttcg gtcgatccgg caacagcccg gaaagcgtcg ccgccgtgga
    14761 actggcgaat cagtttgtac cggaatgcta tcacctgccg atcacctgca acgaagcggg
    14821 cgctctttac caaaacgcga tcaacagcga caacgcgttt gccctgctga tgcccgcaga
    14881 aacgcacgat cgcggctttg cgatgaccag cagcattacc accatgatgg ccagctgcct
    14941 cgcggttttc gcacctgaga cgatcaacag ccaaaccttc cgcgatgtgg cagatcgttg
    15001 ccaggaaatc ctgacctcac tgggcgattt cagcgaaggt gtgtttggtt acgcaccgtg
    15061 gaaacggatc gtttatctcg gcagcggtgg cttacagggc gcagcacgcg agtcggcgct
    15121 gaaagtactg gaactgacag cgggtaaact ggcggccttt tatgattccc cgaccggatt
    15181 ccgtcatggc ccgaaatcgc tggtcgataa cgaaacgctg gtggtggtgt ttgtctccag
    15241 ccacccttac acccgtcagt atgatcttga tctgctggca gaactccgcc gcgataacca
    15301 ggcattgcgc gtaatcgcca tcgccgcgga aagcaacgac gttattaccg ccggtccaca
    15361 tatcatcctg ccgccgtccc gtcactttat cgacgttgag caggcatttt gcttcctgat
    15421 gtacgcccag acgtttgcac tgatgcagtc gctgcacatg ggtaatacgc cggatacccc
    15481 atcagccagt ggcaccgtta accgcgtggt gcaaggcgta atcattcatc cgtggcaggc
    15541 ataagaggat cgcattatga gcattatctc caccaaatat ctgttacagg atgcccaggc
    15601 caatggctac gcggtgcctg cctttaacat tcataacgcc gagacgatcc aggcgatcct
    15661 cgaagtgtgc agtgaaatgc gatcgccggt gatcctcgcc gggacgccgg ggacctttaa
    15721 gcatatcgcg ctggaagaga tctacgccct gtgtagcgcc tattccacga cctataacat
    15781 gccgctggca ctgcatcttg atcaccacga atcgctggat gatattcgcc gtaaagtcca
    15841 cgcaggcgtg cgcagtgcga tgatcgacgg cagccacttc ccgtttgccg agaacgtgaa
    15901 gctggtgaaa tcggttgtcg acttctgcca ctcacaggat tgcagcgtgg aagcagaact
    15961 gggccgcctg ggcggtgttg aagatgacat gagcgttgac gccgaaagtg cattcctgac
    16021 cgatccacaa gaagctaaac gctttgtcga actgactggc gtcgacagcc tggcggtagc
    16081 gattggtacg gcgcacggct tatacagcaa aacgccgaag attgatttcc agcggctggc
    16141 ggaaattcgt gaagtggtgg atgttcctct ggtgctgcat ggtgccagcg atgtcccgga
    16201 tgaatttgtc cgtcgcacta ttgaacttgg cgtcacaaaa gtgaacgttg ccacagaatt
    16261 aaaaatagcc ttcgctggcg cggttaaagc ctggtttgcg gaaaatccgc agggtaatga
    16321 tcctcgttat tatatgcgcg tcggaatgga tgcgatgaaa gaagttgtca gaaataaaat
    16381 taatgtctgt ggttcagcga atcgaatttc agcataatca ttagtttttt atgatttatc
    16441 ccaatgtact tcccgattaa tatcggggag tgccttaatg gaaaaggaga tgactaaacc
    16501 ttaataaata cataagtaca atatcgcaac aataatatat ttaaaaaaat tatattattc
    16561 aactttatgg tgaggattac acaatgagca gtccaaatat tctcttaacc cgtattgata
    16621 accgtctggt tcacggtcag gttggcgtga cctggacatc caccatcggt gcgaatctgt
    16681 tggtagtcgt ggatgatgtt gtcgctaacg atgatattca acagaaatta atgggtatta
    16741 ccgcagaaac ctacgg
//
LOCUS       DADXDL010000102        16705 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.102, whole genome shotgun sequence.
ACCESSION   DADXDL010000102 DADXDL010000000
VERSION     DADXDL010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16705)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16705)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16705
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.102"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            119..2497
                     /gene="ppsA"
                     /locus_tag="IRB70_003991"
     CDS             119..2497
                     /gene="ppsA"
                     /locus_tag="IRB70_003991"
                     /EC_number="2.7.9.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate synthase"
                     /protein_id="HBC0633843.1"
                     /translation="MSNNGSSPLVLWYNQLGMNDVDRVGGKNASLGEMITNLSGMGVS
                     VPNGFATTADAFNQFLDQSGVNQRIYELLDKTDIDDVTQLAKAGAQIRQWIIDTPFQP
                     ELENAIREAYAQLSADDENASFAVRSSATAEDMPDASFAGQQETFLNVQGFDAVLVAV
                     KHVFASLFNDRAISYRVHQGYDHRGVALSAGVQRMVRSDLASSGVMFSIDTESGFDQV
                     VFITSAWGLGEMVVQGAVNPDEFYVHKPTLAANRPAIVRRTMGSKKIRMVYAPTQEHG
                     KQVKIEDVPQEQRDIFSLTNEEVQELAKQAVQIEKHYGRPMDIEWAKDGHTGKLFIVQ
                     ARPETVRSRGQVMERYTLHSQGKIIAEGRAIGHRIGAGPVKVIHDISEMNRIEPGDVL
                     VTDMTDPDWEPIMKKASAIVTNRGGRTCHAAIIARELGIPAVVGCGDATERMKDGENV
                     TVSCAEGDTGYVYAELLEFSVKSSSVETMPDLPLKVMMNVGNPDRAFDFACLPNEGVG
                     LARLEFIINRMIGVHPRALLEFDDQEPQLQNEIREMMKGFDSPREFYVGRLTEGIGTL
                     GAAFYPKRVIVRLSDFKSNEYANLVGGERYEPDEENPMLGFRGAGRYVSDSFRDCFAL
                     ECEAVKRVRNDMGLTNVEIMIPFVRTVDQAKAVVEELARQGLKRGENGLKIIMMCEIP
                     SNALLAEQFLEYFDGFSIGSNDMTQLALGLDRDSGVVSELFDERNDAVKALLSMAIRA
                     AKKQGKYVGICGQGPSDHEDFAAWLMEEGIDSLSLNPDTVVQTWLSLAELKK"
     gene            complement(2554..4200)
                     /gene="fadK"
                     /locus_tag="IRB70_003992"
     CDS             complement(2554..4200)
                     /gene="fadK"
                     /locus_tag="IRB70_003992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310435.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="medium-chain fatty-acid--CoA ligase"
                     /protein_id="HBC0633844.1"
                     /translation="MKVTLTFNEQRRAAYRQQGLWGDASLADYWQQTARAMPDKIAVV
                     DNHGATYTYSALDHAASCLANWMLAKGIESGDRIAFQLPGWCEFTVIYLACLKIGAVS
                     VPLLPSWREAELVWVLNKCQAKMFFAPTLFKQTRPVDLILPLQNQLPQLQQIVGVDKL
                     APATSSLSLSQILADNTPLTTAITVHGDELAAVLFTSGTEGLPKGVMLTHNNILASER
                     AYCARLNLTWQDVFMMPAPLGHATGFLHGVTAPFLIGARSVLLDIFTPAACLALLEQQ
                     RCTCMLGATPFVYDLLNLLEKQPADLSALRFFLCGGTTIPKKVARECQQRGIKLLSVY
                     GSTESSPHAVVNLDDPLSRFMHTDGYAAAGVEIKVVDNARKTLPPGCEGEEASRGPNV
                     FMGYFDEPELTARALDEEGWYYSGDLCRMDEAGYIKITGRKKDIIVRGGENISSREVE
                     DILLQHPKIHDACVVAMPDERLGERSCAYVVLKAPHHSLSLEDVVAFFSRKRVAKYKY
                     PEHIVVIEKLPRTASGKIQKFLLRKDIMRRLTQDVCEEIE"
     gene            complement(4257..4550)
                     /locus_tag="IRB70_003993"
     CDS             complement(4257..4550)
                     /locus_tag="IRB70_003993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin family protein"
                     /protein_id="HBC0633845.1"
                     /translation="MSQNATVNVDIKLGVNKFHVDEGHPHIILAANPDINEFRKLMKA
                     CPAGLYKQDDAGNIHFDSAGCLECGTCRVLCGNTILEQWQYPAGTFGIDFRYG"
     gene            complement(4547..5836)
                     /locus_tag="IRB70_003994"
     CDS             complement(4547..5836)
                     /locus_tag="IRB70_003994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBC0633846.1"
                     /translation="MSDDKFDAIVVGAGVAGSVAALVMARAGLDVLVIERGDSAGCKN
                     MTGGRLYAHTLEAIIPGFAVSAPVERKVTREKISFLTEESAVTLDFHREQPDVPQHAS
                     YTVLRNRLDPWLMEQAEQAGAQFIPGVRVDALVREGNKVTGVQAGDDILEANVVILAD
                     GVNSMLGRSLGMVPASDPHHYAVGVKEVIGLTPEQIKDRFNITGEEGAAWLFAGSPSD
                     GLMGGGFLYTNKDSISLGLVCGLGDIAHAQKSVPQMLEDFKQHPAIRPLISGGKLLEY
                     SAHMVPEGGLAMVPQLVNDGVMIVGDAAGFCLNLGFTVRGMDLAIASAQAAATTVIAA
                     KERADFSASSLAQYKRELEQSCVMRDMQHFRKIPALMENPRLFSQYPRMVADIMNEMF
                     TIDGKPNQPVRKMIMGHAKKIGLINLLKDGIKGATAL"
     gene            complement(5891..6829)
                     /locus_tag="IRB70_003995"
     CDS             complement(5891..6829)
                     /locus_tag="IRB70_003995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein subunit alpha"
                     /protein_id="HBC0633847.1"
                     /translation="MSQLNSVWVFSDNPERYAALFGGAQQWGQQVYAIVQNTNQAQAV
                     MPYGPKCIYVLEQNDALQRTENYAESIAALLKDKHPSMLLLAATKRGKALAARLSVQL
                     NAALVNDATAVDIVDGHICAEHRMYGGLAFAQEKINSPLAIITLAPGVQEPCTSDTSH
                     QCPTETVPYVAPRHEILCRERRAKAASSVDLSKAKRVVGVGRGLAAQDDLKMVHELAA
                     VLNAEVGCSRPIAEGENWMERERYIGVSGVLLKSDLYLTLGISGQIQHMVGGNGAKVI
                     VAINKDKNAPIFNYADYGLVGDIYKVVPALISQLSR"
     gene            complement(6849..7613)
                     /locus_tag="IRB70_003996"
     CDS             complement(6849..7613)
                     /locus_tag="IRB70_003996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="electron transfer flavoprotein"
                     /protein_id="HBC0633848.1"
                     /translation="MKIITCFKLVPEEQDIVVTPEYTLNFDNADAKISQFDLNAIEAA
                     SQLASDDDEIAALTIGGSLLQNSKVRKDVLSRGPHSLYLVQDAQLEHALPLDTAKALA
                     AAVEKIGFDLLIFGEGSGDLYAQQVGLLVGELLQLPVINAVSAIQRQGNTLVIERTLE
                     DDVEVIELSVPAVLCVTSDINVPRIPSMKAILGAGKKPVNQWQASDIGWSQSAPLAEL
                     TGIRVPPQTERKHIILDNDSPEAIAELAEHLKKALN"
     gene            7929..8840
                     /locus_tag="IRB70_003997"
     CDS             7929..8840
                     /locus_tag="IRB70_003997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBC0633849.1"
                     /translation="MYQRCFDNASETLFVAGKTPRLSRFAFSDDPKWESGHHVHDNET
                     ELIYVKKGVARFTIDSSLYVAHADDIVVIERGRLHAVASDVNDPATTCTCALYGFQFQ
                     GAEENQLLQPHSCPVIAAGQGKEVIKTLFNELSMILPQSKNSQTSSLWDAFAYTLAIL
                     YYENFKNAYRSEQGYIKKDVLIKDILFYLNNNYREKITLEQLSKKFRASVSYICHEFT
                     KEYRISPINYVIQRRMTEAKWSLTNTELSQAEISWRVGYENVDHFAKLFLRHVGCSPS
                     DYRRQFKNCFAEQEILSEFPQPVSLAG"
     gene            complement(8883..10034)
                     /locus_tag="IRB70_003998"
     CDS             complement(8883..10034)
                     /locus_tag="IRB70_003998"
                     /EC_number="1.3.8.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310429.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBC0633850.1"
                     /translation="MDFSLTEEQELLLASIRELITTNFPEEYFRTCDQNGTYPREFMR
                     ALADNGISMLGVPEEFGGIPADYVTQMLALMEVSKCGAPAFLITNGQCIHSMRRFGSA
                     EQLRKTAESTLETGDPAYALALTEPGAGSDNNSATTTYTRKNGKVYINGQKTFITGAK
                     EYPYMLVLARDPQPKDPKKAFTLWWVDSSKPGIKINPLHKIGWHMLSTCEVYLDNVEV
                     EESDMVGEEGMGFLNVMYNFEMERLINAARSTGFAECAFEDAARYANQRIAFGKPIGH
                     NQMIQEKLALMAIKIDNMRNMVLKVAWQADQHQSLRTSAALAKLYCARTAMEVIDDAI
                     QIMGGLGYTDEARVSRFWRDVRCERIGGGTDEIMIYVAGRQILKDYQNK"
     gene            complement(10048..11643)
                     /locus_tag="IRB70_003999"
     CDS             complement(10048..11643)
                     /locus_tag="IRB70_003999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl CoA:acetate/3-ketoacid CoA transferase"
                     /protein_id="HBC0633851.1"
                     /translation="MKPVKPPRINGRVPVLSAQEAVNYIPDEATLCVLGAGGGILEAT
                     TLITALADKYKQTQTPRNLSIISPTGLGDRADRGISPLAQEGLVKWALCGHWGQSPRI
                     SDLAEQNKIIAYNYPQGVITQTLRAAAAHQPGIISDIGIGTFVDPRQQGGKLNEVTKE
                     DLIKLVEFDNKEYLYYKAIAPDIAFIRATTCDSEGYATFEDEVMYLDALVIAQAVHNN
                     GGIVMMQVQKMVKKATLHPKSVRIPGYLVDIVVVDPDQTQLYGGAPVNRFISGDFTLD
                     DSTKLSLPLNQRKLVARRALFEMRKGAVGNVGVGIADGIGLVAREEGCADDFILTVET
                     GPIGGITSQGIAFGANVNTRAILDMTSQFDFYHGGGLDVCYLSFAEVDQHGNVGVHKF
                     NGKIMGTGGFIDISATSKKIVFCGTLTAGSLKTEITDGKLNIVQEGRVKKFIRELPEI
                     TFSGKIALERGLDVRYITERAVFTLKEDGLHLIEIAPGVDLQKDIFDKMDFTPVISPE
                     LKLMDERLFIDAAMGFVLPEAAH"
     gene            complement(11789..12547)
                     /gene="aroD"
                     /locus_tag="IRB70_004000"
     CDS             complement(11789..12547)
                     /gene="aroD"
                     /locus_tag="IRB70_004000"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBC0633852.1"
                     /translation="MKTVTVKDLVIGTGAPKIIVSLMAKDIASVKSEALAYREADFDI
                     LEWRVDHYADLSNVESVMAAAKILRETMPEKPLLFTFRSAKEGGEQAISTEAYIALNR
                     AAIDSGLVDMIDLELFTGDDQVKETVAYAHAHDVKVVMSNHDFHKTPEAEEIIARLRK
                     MQSFDADIPKIALMPQSTSDVLTLLAATLEMQEQYADRPIITMSMAKTGVISRLAGEV
                     FGSAATFGAVKKASAPGQISVNDLRTVLTILHQA"
     gene            complement(12578..13444)
                     /gene="ydiB"
                     /locus_tag="IRB70_004001"
     CDS             complement(12578..13444)
                     /gene="ydiB"
                     /locus_tag="IRB70_004001"
                     /EC_number="1.1.1.282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinate/shikimate dehydrogenase"
                     /protein_id="HBC0633853.1"
                     /translation="MDVTAKYELIGLMAYPIRHSLSPEMQNKALEKVGLPFTYMAFEV
                     DNDSFPAAIEGLKALKMRGTGVSMPNKQLACEYVDELTPAAKLVGAINTIVNDDGYLR
                     GYNTDGTGHIRAIKESGFDIKGKTMVLLGAGGASTAIGAQGAIEGLKEIKLFNRRDEF
                     FDKALAFAQRVNENTDCVVTVTDLADQQAFAEALASADILTNGTKVGMKPLENESLVN
                     DISLLHPGLLVTECVYNPHMTKLLQQAQQAGCKTIDGYGMLLWQGAEQFTLWTGKDFP
                     LEYVKQVMGFGA"
     gene            complement(13456..14721)
                     /locus_tag="IRB70_004002"
     CDS             complement(13456..14721)
                     /locus_tag="IRB70_004002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310425.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633854.1"
                     /translation="MSQNKAFSTPFILAVLCIYFSYFLHGISVITLAQNMTSLAEKFS
                     TDNAGIAYLISGIGLGRLISILFFGVISDKFGRRAVILMAVIMYLLFFFGIPACPNLT
                     LAYCLAVCVGIANSALDTGGYPALMECFPKASGSAVILVKAMVSFGQMFYPMLVSYML
                     LNNIWYGYGLIIPGILFVLITLMLLKSKFPSQLVDASVANELPQMNSKPLVWLEGVSS
                     VLFGVAAFSTFYVIVVWMPKYAMAFAGMSEAEALKTISYYSMGSLVCVFIFAALLKKM
                     VRPIWANVFNSALATITAAIIYLYPSPLVCNAGAFVIGFSAAGGILQLGVSVMSEFFP
                     KSKAKVTSIYMMMGGLANFVIPLITGYLSNIGLQYIIVLDFTFALLALITAIIVFIRY
                     YRVFIIPENDVRFGEHKFSTRLNTIKHRG"
     gene            complement(14948..16162)
                     /locus_tag="IRB70_004003"
     CDS             complement(14948..16162)
                     /locus_tag="IRB70_004003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633855.1"
                     /translation="MKNPYYPTALGLYFNYLVHGMGVILMSLNMASLETLWQTNAAGV
                     SIVISSLGIGRLSVLLFAGLLSDRFGRRPFIMLGMCCYMAFFFGILHTNNIIIAYVFG
                     FLAGMANSFLDAGTYPSLMEAFPRSPGTANILIKAFVSSGQFLLPLIISLLVWAELWF
                     GWSFMIAAGIMFINALFLYRCTFPPHPGRRLPVIKKTTSSTEHRCSIIDLASYTLYGY
                     ISMATFYLVSQWLAQYGQFVAGMSYTMSIKLLSIYTVGSLLCVFITAPLIRNTVRPTT
                     LLMLYTFISFIALLTVCLHPTFYVVIIFAFVIGFTSAGGVVQIGLTLMAERFPYAKGK
                     ATGIYYSAGSIATFTIPLITAHLSQRSIADIMWFDTAIAAIGFILALFIGLRSRKETR
                     HHSLKENVAPGG"
     gene            complement(16262..16618)
                     /locus_tag="IRB70_004004"
     CDS             complement(16262..16618)
                     /locus_tag="IRB70_004004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707588.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdiL family protein"
                     /protein_id="HBC0633856.1"
                     /translation="MNAYELQALRHIFAMTIDECATWIAQTGDGESWRQWENGKCAIP
                     DCVVEQLLAMRQQRKKHLHAIIEKINNRIGNNTMRFFPDLTAFQQVYPDGNFIDWKIY
                     QSVAAELYAHDLERLC"
BASE COUNT         4288 a         4157 c         4048 g         4212 t
ORIGIN      
        1 agtaaaaaat ataattgctt gaacgattca ccgttttttt catccggtta aatatgcaaa
       61 gataaatgcg cagaaatgtg tttctcaaac cgttcattta tcacaaaagg attgttcgat
      121 gtccaacaat ggctcgtcac cgctggtgct ttggtataac caactcggca tgaatgatgt
      181 agacagggtt gggggcaaaa atgcctccct gggtgaaatg attactaacc tttccggaat
      241 gggtgtttcc gttccgaatg gtttcgccac aaccgccgac gcgtttaacc agtttctgga
      301 ccaaagcggc gtaaaccagc gcatttatga actgctggat aaaacggata ttgacgatgt
      361 tacccagctt gcgaaagcgg gcgcgcaaat ccgccagtgg attatcgaca ctcccttcca
      421 gcctgagctg gaaaacgcca tccgcgaagc ctatgcacag ctttccgccg atgacgaaaa
      481 cgcctcgttt gcggtgcgtt cctccgctac tgcagaagat atgccggacg cttcttttgc
      541 cggtcagcag gaaaccttcc tcaacgttca gggttttgac gccgttctcg tggcagtgaa
      601 acatgtattt gcttctctgt ttaacgatcg cgccatctct tatcgtgtgc accagggtta
      661 cgatcaccgt ggcgtggcgc tctccgccgg tgttcagcgg atggtgcgct ccgacctcgc
      721 atcttctggc gtgatgttct ccattgatac cgaatccggc tttgaccagg tggtgtttat
      781 cacttccgca tggggccttg gtgaaatggt cgtgcagggt gcggttaacc cggatgagtt
      841 ttacgtgcac aaaccgacac tggcggcgaa tcgcccggct atcgtgcgcc gcaccatggg
      901 gtcgaaaaaa atccgcatgg tttacgcgcc gacccaggag cacggcaagc aggttaaaat
      961 cgaagacgta ccgcaggaac agcgtgacat cttctcgctg accaacgaag aagtgcagga
     1021 actggcaaaa caggccgtac aaattgagaa acactacggt cgcccgatgg atattgagtg
     1081 ggcgaaagat ggccacaccg gcaaactgtt cattgtgcag gcgcgtccgg aaaccgtgcg
     1141 ctcacgcggt caggtcatgg agcgttatac gctgcattca cagggtaaga ttatcgccga
     1201 aggccgtgct atcggtcatc gcatcggcgc gggtccggtg aaagtcatcc atgacatcag
     1261 cgaaatgaac cgcatcgaac ctggcgacgt gctggttact gacatgaccg acccggactg
     1321 ggaaccgatc atgaagaaag catctgccat cgtcaccaac cgtggcggtc gtacctgtca
     1381 cgcggcgatc atcgctcgtg aactgggcat tccggcggta gtgggctgtg gagatgcaac
     1441 agaacggatg aaagacggtg agaacgtcac tgtttcttgt gccgaaggtg ataccggtta
     1501 tgtctatgcg gagttgctgg aatttagcgt gaaaagctcc agcgtagaaa cgatgccgga
     1561 cctgccgttg aaggtgatga tgaacgtcgg taacccggac cgagctttcg acttcgcctg
     1621 tctgccgaac gaaggcgtgg gacttgcgcg tctggaattt atcatcaacc gtatgattgg
     1681 cgtccaccca cgcgcgctgc ttgagtttga cgatcaagaa ccgcagttgc aaaacgaaat
     1741 ccgcgagatg atgaaaggtt ttgattctcc gcgtgaattt tacgttggtc gtctgactga
     1801 agggatcggg acgctgggtg ccgcgtttta tccgaagcgc gtcattgtcc gtctctctga
     1861 ttttaaatcg aacgaatatg ccaacctggt cggtggtgag cgttacgagc cagatgaaga
     1921 gaacccgatg ctcggcttcc gtggcgcggg ccgctatgtt tccgacagct tccgcgactg
     1981 cttcgcgctg gagtgtgaag cagtgaaacg tgtgcgcaac gacatggggc tgaccaacgt
     2041 tgagatcatg atcccgttcg tgcgtaccgt agatcaggcg aaagcggtgg ttgaggaact
     2101 ggcgcgtcag gggctgaaac gcggtgagaa cgggctgaaa atcatcatga tgtgtgaaat
     2161 cccgtccaac gccttgctgg ccgagcagtt cctcgaatat ttcgacggct tctcaattgg
     2221 ctcaaacgac atgacgcagc tggcgctcgg tctggatcgt gactccggcg tggtatctga
     2281 actgttcgat gagcgcaacg atgcggtgaa agcactgctg tcgatggcga ttcgtgccgc
     2341 gaagaaacag ggcaaatatg tcgggatttg cggtcagggt ccgtccgacc acgaagactt
     2401 tgccgcatgg ttgatggaag aggggatcga tagcctgtct ctgaacccgg atactgtggt
     2461 gcaaacctgg ttaagcctgg ctgaactgaa gaaataaaat aaatccccgg cggcgttttg
     2521 tcgccgggtt tatgtgatcc ccgaagatga aacttattca atctcttcac agacatcctg
     2581 agttaatcgc cgcataatat ctttccttaa caaaaacttt tgtattttac ctgaggcagt
     2641 gcgcggtagt ttttcgatta ccacgatatg ttcaggatat ttatatttcg cgacccgttt
     2701 acggctaaaa aatgccacta catcttccag cgataatgaa tgatgcggtg ctttcagcac
     2761 gacataagcg catgaacgtt cacctaagcg ttcatcgggc attgcaacca cacaagcatc
     2821 gtgaatttta ggatgctgca ataaaatatc ttccacttca cggctgctaa tattttcgcc
     2881 gccgcggaca ataatatctt tcttgcgccc ggttattttt atatagccag cctcatccat
     2941 gcggcagaga tcgccgctgt aataccagcc ttcttcatcc agcgcacggg cggttaattc
     3001 aggttcatca aaatacccca taaacacatt ggggccacgc gaggcttctt caccttcgca
     3061 acctggcggt aaggtcttgc gtgcgttatc gaccacttta atctctacac ctgcggcagc
     3121 gtaaccatcg gtgtgcataa agcgcgacaa aggatcatcg agattcacca ccgcatgcgg
     3181 cgaactttct gtggaaccat aaacacttaa taatttaatg ccgcgctgct ggcattctcg
     3241 cgccactttt ttggggattg tggtaccgcc acaaagaaag aagcgcagcg ctgaaaggtc
     3301 tgcgggttgt ttctctagta aattcaaaag atcatagaca aacggcgttg cgccgagcat
     3361 acaggtgcaa cgctgctgct caagcagcgc gagacacgca gcaggagtga aaatatctaa
     3421 caacacgctg cgagcaccaa tcaaaaaagg tgctgttacg ccatgcagaa agcccgttgc
     3481 gtgaccaagt ggcgcaggca tcataaagac atcctgccag gtcagattta gccgcgcgca
     3541 ataagcccgc tcactggcga gaatattgtt atgcgttagc atcacgccct ttggcagacc
     3601 ctcggttccg gaggtaaata gcacagccgc taattcatcg ccgtggaccg ttatcgccgt
     3661 ggtcagagga gtattgtcgg cgagaatctg acttaatgag agggaagagg tggcgggagc
     3721 cagtttgtcc acgccgacaa tttgttgtag ttgtggaagc tgattttgca gcggcaggat
     3781 taaatctacc ggacgcgttt gtttaaacaa cgtcggtgca aagaacattt ttgcctgaca
     3841 cttattgagt acccatacta gttctgcttc ccgccaggaa ggcaacagcg gtacggaaac
     3901 cgcaccgatt ttcaggcagg caagatagat aacggtaaat tcacaccagc ctggcagttg
     3961 aaatgcgatg cgatcgcctg attcaatacc cttcgctaac atccagtttg ccagacagct
     4021 cgcggcgtga tcgagcgcgc tataggtgta cgttgcacca tgattgtcga ccacggcaat
     4081 tttgtctggc atcgcacgag cggtctgctg ccagtaatcg gccagtgaag catcgcccca
     4141 taacccttgc tgacgatacg ccgcacgacg ttgttcgtta aacgttaatg tcactttcat
     4201 tttggactct cgaaacagaa catcaggccc gagatgcggg cctgtgggat gcatgattag
     4261 ccgtagcgaa aatcaatacc gaaggtgcct gcgggatatt gccactgttc gagaatagtg
     4321 ttaccgcaca gcacccgaca ggtgccgcac tccagacaac cggcggaatc gaaatgaatg
     4381 tttcctgcgt catcctgctt ataaagtccg gcagggcagg ctttcattaa tttacggaat
     4441 tcattgatat cgggatttgc cgccaaaatg atatgcgggt ggccctcatc aacatggaat
     4501 ttattgacgc ctaatttgat gtcgacgtta accgtagcgt tctggctcat agcgcggttg
     4561 ctcccttaat gccatctttc agcaagttga tcagcccaat tttcttcgcg tgtcccatga
     4621 tcattttgcg taccggctgg tttggtttgc cgtcaatggt gaacatctcg ttcatgatgt
     4681 cggcgaccat gcgcggatac tgactaaaca ggcgcggatt ttccatcagc gccgggatct
     4741 tgcgaaaatg ctgcatatca cgcataacac aactttgttc cagctcacgt ttgtattgcg
     4801 ccagactgct ggcggagaaa tccgcgcgtt ctttggctgc aatcactgtt gtggcggcag
     4861 cctgagctga tgcaatggct aaatccatgc cgcgaactgt aaaacccaaa ttcaggcaga
     4921 agcctgcggc gtcaccaacg atcatcacgc catcgttaac cagctgcggc accattgcca
     4981 gaccgccctc cggcaccata tgcgcggaat attcaagcag tttgcctccg ctaatcagcg
     5041 ggcgaatggc ggggtgttgt ttaaaatctt ccagcatttg tggcacgctt ttttgcgcat
     5101 gggcgatatc acccaaccca caaaccagcc ccaacgatat ggaatcctta ttggtataga
     5161 ggaatccgcc gcccatcagg ccgtcagaag gggaaccggc aaacagccag gcggcacctt
     5221 cctcgcccgt aatattaaag cgatccttga tctgttctgg tgtgaggcca ataacctctt
     5281 taacaccaac agcgtaatga tgcggatcgg aagcgggaac cattcccagc gagcggccaa
     5341 gcatcgagtt aacgccatca gccagaatca ccacattcgc ttcgagaata tcatccccag
     5401 cctgcacgcc agtgaccttg tttccttcac gaaccagcgc atcgacgcga acgcccggga
     5461 taaactgcgc gcccgcctgc tcggcttgtt ccatcaacca cgggtccaga cgattacgca
     5521 atacggtata agacgcgtgt tgcggaacat ctggttgctc gcggtgaaaa tcgagggtaa
     5581 cggcgctttc ttcggttaag aaggagattt tctcgcgtgt gaccttgcgt tctaccggcg
     5641 ctgatactgc aaagcctgga atgattgctt caagtgtgtg ggcataaaga cgcccgccgg
     5701 tcatgttttt acatccggca ctgtcgccgc gttctatcac caggacatcc agcccggctc
     5761 gcgccatgac tagtgcggca acgctaccag caacgcccgc accgaccaca atggcatcaa
     5821 atttgtcatc cgacatgcgt tatgctccct tcccgctgcg tttacagcgg gagatgtggt
     5881 tgaaagggaa ttagcgactc aactggctaa tcagggcagg gacgactttg tagatatcgc
     5941 ccaccagacc gtagtcggca tagttgaaga ttggcgcatt tttatcttta ttgatggcga
     6001 caatcacttt tgcgccgttg ccgccaacca tatgttggat ctgcccggag atccccagcg
     6061 tcaggtagag atcggatttc agcaacacgc cggagacacc gatataacgt tcacgctcca
     6121 tccaattctc gccttcggca attggacgtg aacagccgac ttcagcattc agcaccgccg
     6181 ccagttcgtg gaccattttc aggtcatcct gcgccgccag accacgaccg acgccaacca
     6241 cacgttttgc tttgctcagg tccacgctgc ttgcggcttt cgcacggcgt tcgcgacaga
     6301 gaatttcatg acgcggagca acataaggta ccgtttctgt cgggcactga tgagaggtat
     6361 cactggtgca cggttcctga acaccgggtg caagggtaat gatcgccagc gggctgttga
     6421 tcttttcctg tgcgaacgct aacccgccat acatccggtg ttcggcgcaa atgtgaccat
     6481 cgacaatatc caccgccgtg gcatcgttca ccagcgccgc attcagttgc acacttaacc
     6541 gtgctgccag agctttacca cgtttcgtcg cggccagcag caacatagaa gggtgtttat
     6601 ctttcagcag ggcagcaatg ctttcggcgt aattttcagt acgttgcagc gcatcatttt
     6661 gctcaagaac ataaatacat tttggaccat aaggcataac tgcctgcgcc tggttggtat
     6721 tttgtacaat ggcatacacc tgttggcccc attgctgcgc gccgccaaac agtgcagcat
     6781 aacgttcagg attatcgcta aagacccaga cgctgtttaa ttgactcatc gtttcttctc
     6841 cgtaggcttc agttcagggc ttttttcaga tgttccgcca gctcggcaat ggcctccggc
     6901 gaatcgttat cgagaatgat gtgcttacgt tctgtttgcg gcggtacgcg aatgccggtc
     6961 agttcagcaa gtggtgcgct ctggctccag ccaatatcac ttgcctgcca ctgatttacc
     7021 ggttttttac ccgcgccgag gatggctttc atcgaaggaa tacgtggtac gttaatatcg
     7081 gaggtgacgc agagcacggc tggaacagag agttcaataa cttcaacatc atcttcaagc
     7141 gtgcgttcaa tcaccagtgt attgccctga cgctgaatag cactcactgc attaatcacc
     7201 ggaagttgca gaagttctcc gaccagcaag ccaacctgct gggcataaag gtcgccggaa
     7261 ccttcaccaa agatcagtaa atcgaagccg atcttttcaa ctgctgccgc cagcgccttt
     7321 gcggtatcga gaggcagtgc atgttcaagt tgcgcatcct gcaccaaata caggctgtgc
     7381 ggcccgcggg atagcacgtc ttttcgcact ttcgagttct gcaacaatga gccaccaatg
     7441 gtcagcgcgg ctatctcatc gtcatctgat gcaagctggc ttgcagcttc aatggcattg
     7501 agatcgaact ggctgatttt ggcgtcggca ttgtcgaaat tcagggtata ttctggagtg
     7561 acaacaatgt cctgttcttc aggcaccagc ttaaagcagg ttattatttt catgatttct
     7621 cctgtgagtc gcatacggaa ccatctccga tggaaggtaa atatggcctg aaaatagtgt
     7681 gcgatagcgg tgcggggttt tcgacggagc aagctgtttt ccttgccaac aatcttgcaa
     7741 aaaaaatgcg atcgctaaaa caaaagtgca atttgcggca atatagttat tccatgaccg
     7801 tacaatcttg cattcagtgt aaataatctt gtttagctct cgctaaacgc ggttgtataa
     7861 ccgcaataca cgccgtattt tatccggcat atattgtttt tgtttgctca tggaataggg
     7921 aggttgtcat gtatcaacgc tgttttgata atgccagtga aacgctgttt gtcgccggta
     7981 aaacgccacg gctttcacgt ttcgcattta gcgatgatcc aaaatgggag tctggacatc
     8041 acgttcatga caatgaaacc gagctgattt acgtcaagaa aggggtagca aggtttacca
     8101 tcgattcttc gttatatgtc gcgcatgccg atgacattgt ggtgatagaa cgtggcaggc
     8161 tgcatgcggt ggcctctgac gttaacgatc cggcaacgac gtgtacctgt gcgctgtacg
     8221 gctttcagtt tcagggggct gaggaaaatc agctactgca accgcattct tgcccggtaa
     8281 ttgccgcagg gcagggaaaa gaagtcatta aaaccttatt taatgagcta agtatgattt
     8341 tgccgcaaag taaaaatagc caaacatctt cgttatggga cgcatttgcc tatacgttag
     8401 caattcttta ctacgaaaac tttaaaaatg cttatcgttc ggagcaggga tatattaaaa
     8461 aagatgttct gataaaagat attcttttct atctgaataa taactatcgc gaaaaaatca
     8521 ctttagagca gttatcgaaa aaatttcgtg ccagcgtcag ttatatctgc catgaattta
     8581 ccaaagagta tcgtatttcc cctattaact atgttattca acggcgtatg acggaagcga
     8641 aatggtcact cactaatact gaattatcac aggcagagat ttcctggcgt gtgggttatg
     8701 aaaatgtcga tcactttgcc aaactgtttt tgcgccatgt cggctgttcg cccagcgatt
     8761 accgcaggca atttaaaaac tgttttgcgg aacaagaaat cctatctgaa tttcctcaac
     8821 cagtaagtct tgccggataa atctggcggc gcagtttgtt aagaagctgc gccgcctgca
     8881 gattatttgt tctgataatc tttcaggatc tgccgacccg ctacgtaaat cataatttcg
     8941 tctgtaccgc cgccgatacg ttcacaacgg acatcacgcc agaagcggga cacgcgcgcc
     9001 tcatcggtat agcccagacc gcccatgatt tgaatcgcat catcaatgac ttccattgcg
     9061 gtacgtgcgc agtacagttt tgccagcgcc gcgctggtgc gcagtgactg atgctgatcg
     9121 gcttgccatg ccactttcaa caccatgttg cgcatgttgt cgatcttaat cgccatcagc
     9181 gccagttttt cctggatcat ctggttatga ccaatgggct taccaaaagc gatacgctgg
     9241 ttggcatagc gggcggcatc ttcgaatgcg cattcggcaa agccggtgct gcgcgcggcg
     9301 ttgatcaggc gctccatctc aaagttgtac atcacattga ggaaacccat tccttcttcg
     9361 cccaccatgt cgctctcttc aacttccacg ttgtcgagat agacttcgca ggtgctgagc
     9421 atatgccagc cgattttatg cagtggattg attttaatgc cgggtttact ggagtcgacc
     9481 caccacagag taaaggcctt tttcggatct ttcggttgcg gatcgcgcgc caacaccagc
     9541 atatatggat actctttcgc accggtaata aaggttttct gtccgttgat gtaaaccttg
     9601 ccgtttttac gcgtgtaagt ggtagtggca ctgttgttgt ctgagcctgc gcctggctcc
     9661 gtcaatgcca gggcataggc gggatcaccc gtttccagtg tgctctctgc cgttttacgt
     9721 agctgctctg cagaaccgaa acggcgcata ctgtgaatac attgaccgtt ggtaatcaaa
     9781 aatgccggag caccgcattt tgacacttcc atcagcgcca gcatttgggt gacgtaatcc
     9841 gcagggatac caccaaattc ttccggcacg ccaagcatgg aaataccgtt atccgccagt
     9901 gcccgcataa actcacgcgg gtatgtcccg ttttgatcgc aggtgcggaa atactcttcc
     9961 ggaaagttag tcgtaatcag ttcgcgaata ctggccagca gcagttcttg ttcttcagtt
    10021 aaagaaaaat ccatcattat actcctgtta atgagccgct tcaggcagga caaaacccat
    10081 cgccgcatcg ataaataatc tttcgtccat cagtttgagt tctggcgaaa tcactggggt
    10141 gaaatccatt ttgtcgaaaa tatctttttg taaatcgacg ccaggagcga tttcgattaa
    10201 atgcaggccg tcttctttta acgtgaatac ggcgcgctca gtgatataac gaacatccag
    10261 ccctcgctcg agagcgattt ttccgctgaa agttatttcc ggtagttccc gaataaattt
    10321 cttcacccgt ccttcctgga cgatatttaa tttgccgtcg gtaatttctg tttttaaact
    10381 gcccgcagtt aatgtgccgc agaaaacgat tttcttcgaa gtggcactga tatcaataaa
    10441 tccaccggtg cccatgattt taccattgaa tttatgcacg ccgacgttac cgtgctggtc
    10501 gacttcagca aaactcaaat aacaaacatc cagaccgcca ccgtgataaa aatcaaactg
    10561 ggacgtcata tccagaatgg cgcgggtatt cacgttcgcg ccaaaggcga tcccctgtga
    10621 agtaataccg ccaatcggac ctgtttctac cgtcagaata aagtcatcag cacaaccttc
    10681 ttcccgggcg accaggccaa tgccgtcagc aataccgacg ccgacattcc ccactgcgcc
    10741 tttgcgcatt tcgaataatg cgcgccgtgc aactaattta cgttggttta ggggcaggct
    10801 aagtttggtg ctgtcatcaa gagtgaagtc accagaaata aagcggttaa ccggcgcacc
    10861 gccatacagt tgggtttgat ccggatcgac caccacaata tccaccagat aacccggaat
    10921 acggacagat ttaggatgca gcgtggcttt cttaaccatt ttctgcacct gcatcatcac
    10981 aataccgccg ttattgtgca ccgcctgggc aataaccaat gcgtcgagat acatcacctc
    11041 atcttcaaaa gtggcgtagc cttcgctgtc gcaggtggta gcgcgaatga aggcgatatc
    11101 tggcgcaatc gctttgtaat agagatattc tttgttatca aactcgacca gtttaatcag
    11161 gtcttcttta gtgacttcat tcagtttgcc gccttgctgg cgtggatcga caaatgttcc
    11221 gatgccaata tcactaataa taccaggctg gtgggctgcg gcggcgcgta aggtttgtgt
    11281 aattactcct tgtggatagt tataagcaat aattttattt tgttctgcga gatcagaaat
    11341 acgcggcgat tgtccccagt gaccgcataa tgcccatttc accagacctt cttgcgccag
    11401 cggactaata ccacggtcgg cgcgatcgcc aagccctgtt ggactaataa tcgataaatt
    11461 acgtggtgtt tgagtctgtt tatatttatc agcaagagca gtaattaacg tggtggcttc
    11521 cagaataccg ccgccagcgc ctaacacaca aagtgttgct tcgtcgggaa tataattcac
    11581 cgcttcctgt gccgacagga ccggcactcg tccattaata cgaggtggtt ttacaggttt
    11641 cattgttaat tcctgattca ggtgtgattt tccctacgcc agatggaaaa ttagcgcaca
    11701 gagactcacg aaatattttt attaaatacg gttaaaaata ctttttttag ttcggcgggg
    11761 gagagtattc ccgccgaaat attattgctt atgcctgatg taaaatagtt aataccgtac
    11821 gcaaatcatt taccgagatt tgccctggcg cagaggcttt ttttaccgca ccaaaagttg
    11881 ccgccgaccc aaatacttca ccagccagac gagaaattac gccagttttt gccatcgaca
    11941 tcgtgatgat tggacgatcg gcatactgct cctgcatctc cagggtcgcg gcaagcaacg
    12001 tcagcacatc gctggtactt tgcggcatca gcgcaatctt aggaatatcg gcgtcgaagg
    12061 actgcatttt gcgcagacgg gcaatgattt cttcggcttc cggcgtttta tggaagtcat
    12121 ggttggacat gacaactttc acatcatgcg cgtgggcgta ggcgacggtt tctttaacct
    12181 gatcatcgcc ggtaaataac tccagatcga tcatatcaac caggccactg tcgatggctg
    12241 cacgattgag tgcaatataa gcctcggtgg aaatcgcctg ctcgccgcct tctttggcac
    12301 tgcggaaggt aaacagcagc ggtttttctg gcatggtttc acggagaatt tttgctgccg
    12361 ccatgacaga ctccacattg gagaggtcgg catagtggtc cacacgccat tccagaatat
    12421 caaagtccgc ttcacgatag gcgagagctt cggatttcac gctggcgata tctttcgcca
    12481 tcagcgagac gatgatttta ggtgcgcccg taccaatgac gagatctttt acagttacgg
    12541 ttttcatttt ttaccctttc tgcacgcggt cagcctgtca ggcaccgaac cccatgacct
    12601 gtttaacata ttccagaggg aaatctttgc cagtccataa cgtgaactgt tcagcccctt
    12661 gccacaacaa catgccgtat ccatcaatcg ttttgcaacc cgcttgttgc gcctgctgca
    12721 ataacttcgt catatgcggg ttatacacgc attcagtgac cagaagtccc ggatgtaaca
    12781 gactgatatc attaaccaat gattcattct caaggggttt catacccact ttggtgccat
    12841 tggttaaaat gtcggcggaa gccagggctt cagcaaaggc ttgctgatcg gcgagatcgg
    12901 taaccgtgac gacacaatcg gtgttttcgt taacccgctg cgcgaaggcg agggctttat
    12961 cgaagaactc atcccgacgg ttaaagagtt taatttcttt taaaccttca attgccccct
    13021 gcgcgccaat cgccgttgag gcacctccgg cccctaacag caccatcgtt ttgcctttga
    13081 tatcaaaacc gctctcttta atggcgcgaa tatggcccgt gccgtcggtg ttatagccac
    13141 gcagatagcc atcatcattt acgatggtgt tgatggcacc caccagcttg gcggctggcg
    13201 ttaattcatc aacatattca cacgccagtt gtttgttcgg catcgacaca ccagttccac
    13261 gcattttgag ggcttttaat ccttcaattg ctgcgggaaa actatcgtta tccacttcaa
    13321 aggccatata ggtaaatggc aatcccactt tttctaaggc tttattctgc atttcaggcg
    13381 ataaactgtg gcggatggga taggccatca acccaatcaa ttcgtatttt gcggtaacat
    13441 ccataattaa ctcctttaac ctctatgctt aattgtgttt aaccgggtgc taaatttatg
    13501 ctcgccaaac cgcacatcat tttcaggaat aatgaaaacg cggtaatagc ggataaaaac
    13561 aataattgcg gtaatcaggg ccagcagcgc gaaagtaaaa tcgagaacaa tgatatattg
    13621 caggccgatg ttcgacagat aaccggtaat cagcggaata acaaagttag ccagtccacc
    13681 catcatcata tatatactgg tgactttggc tttgcttttt gggaaaaact ctgacatgac
    13741 cgaaacgccg agctgtaaaa tgccgccagc tgctgagaaa ccgataacaa aggctccggc
    13801 attacacacc aatggagaag ggtacaggta gataatggca gctgttattg ttgccagtgc
    13861 agagttaaat acattagccc agatgggccg gaccattttt ttcagcagtg cggcaaaaat
    13921 aaagacacag accagcgaac ccatactgta ataagagatg gtttttaatg cctcagcttc
    13981 tgacatacca gcaaaagcca tcgcatattt gggcatccac accacaatca cataaaaggt
    14041 cgagaatgcg gctacaccga acagtactga tgaaacacct tccagccaga ctaacggttt
    14101 gctgttcatt tgcggtaatt cattagctac gctggcgtcc accaactggc tggggaattt
    14161 gcttttcaac agcatcagcg tgatcagtac aaacagaata cccggaataa tcagcccata
    14221 gccgtaccag atgttattga gcaacatata gctcaccagc attgggtaga acatttgccc
    14281 gaatgacacc atcgctttaa ccagtatgac cgccgaacca gaggctttcg gaaagcattc
    14341 catgagcgcg gggtagccac ccgtatccag cgctgagtta gcgataccta cgcacactgc
    14401 cagacagtag gcgagagtta aattcgggca agcagggata ccaaagaaga atagcagata
    14461 cattattact gccattaata tcaccgcccg acgaccaaac ttatcggaga tcacaccgaa
    14521 gaataaaata ctgatcaatc gccccaaacc gataccggaa attaaatagg caatgcccgc
    14581 gttgtcagtg gaaaactttt ctgccagaga tgtcatattt tgggcaagcg taataacact
    14641 aatgccgtgc aggaaatagc tgaagtaaat acaaagaaca gccaggataa atggcgtgct
    14701 gaaagcctta ttttgagaca ttttcacagc tccttgctga aagataattt cgttaccgta
    14761 cgtattgttc tccgacggtt tacataatta ctatactgaa gatgattttc cctgtgtaca
    14821 tggcataaag tttatgtttc caggaatatt gcatgtcata gtttgttttt gatcgcgatt
    14881 ttccttagtt agcgcagaaa gagttattta tccgtaagat cttgcatgac ctgaaaagaa
    14941 tattgcatta cccacccgga gcgacatttt cctttagcga gtgatgccgc gtttctttgc
    15001 gactgcgtaa gccaataaac agtgccagta taaagccgat ggcagcgatg gcggtatcga
    15061 accacataat atcggcaata cttctttgcg aaagatgagc cgtaatcaac ggaatggtaa
    15121 atgttgcaat gctgcccgca ctgtaataga tccccgttgc ttttccttta gcgtagggaa
    15181 aacgttccgc cattaacgtc aggccaattt gtacaacacc gcctgcggag gtaaaaccga
    15241 tgacgaaagc aaatattatc accacataaa atgtgggatg caggcagacg gtgagcaggg
    15301 cgataaatga gataaaggtg tacagcatca gtaatgttgt tgggcgaacg gtattacgaa
    15361 tgagtggagc ggtaataaat acacaaagca gcgaacccac ggtgtagata ctgagtagtt
    15421 tgatcgacat agtgtatgac atgcctgcaa caaattgtcc gtattgtgcc agccactggc
    15481 taaccagata aaacgttgcc attgagatat agccatataa ggtataactg gctaaatcga
    15541 taattgaaca gcgatgttcc gtagagctgg tggttttctt tatgacaggt aagcgacgac
    15601 ccggatgggg tgggaacgta caacggtata aaaacagagc gttaataaac ataatgcctg
    15661 cggcaatcat aaaggaccaa ccgaaccaca gttcagccca cactaacagg ctgataatta
    15721 gcggtaataa aaattgtccg ctggaaacaa atgctttaat taaaatattg gctgtacccg
    15781 gtgagcgtgg aaaagcttcc atcaaactgg gataggtgcc tgcatcgaga aaactgtttg
    15841 ccattcccgc cagaaagcca aaaacataag cgataatgat gttattggtg tgcaggatgc
    15901 caaaaaagaa ggccatatag cagcacatcc cgagcatgat aaaagggcgg cgaccaaagc
    15961 gatcggataa taatcctgca aaaagcaaga cacttaatcg accaatgccc agtgatgaga
    16021 taactatcga gacgcccgcg gcattagtct gccaaagcgt ctccagcgag gccatattca
    16081 ggctcatcaa aatgacgccc ataccatgca ccagataatt aaaatacaac cccagtgcgg
    16141 tagggtaata gggatttttc ataggttcta cttagcaaag gtgctttaaa aagtgtagcg
    16201 atgttgtgtc agtatccgtt cattattgtt gtaacaacga caattccttt ctgtggggaa
    16261 attaacaaag ccgctccaga tcgtgtgcat ataattcagc ggctaccgat tgatagatct
    16321 tccagtcaat aaaattgcca tcagggtaga cttgttgaaa cgcggttaag tcggggaaaa
    16381 aacgcatggt gttgttgccg atgcggttat ttattttctc tatgatggca tgaagatgtt
    16441 tttttcgttg ctgacgcata gccaacagtt gctcgactac acaatcagga atggcgcatt
    16501 tgccattttc ccactgacgc cagctttcac cgtcaccggt ctgggcaatc caggtcgcgc
    16561 attcatcaat agtcatggca aaaatatggc gaagtgcctg gagttcataa gcgttcatcg
    16621 tgtaatggct gcatgaaata aacaataaaa tataaataac attatcagcc tgctgacggc
    16681 ttgaagagag tcacagtatc ttgtg
//
LOCUS       DADXDL010000103        16097 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.103, whole genome shotgun sequence.
ACCESSION   DADXDL010000103 DADXDL010000000
VERSION     DADXDL010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16097)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16097)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16097
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.103"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..454)
                     /gene="folK"
                     /locus_tag="IRB70_004005"
     CDS             complement(<1..454)
                     /gene="folK"
                     /locus_tag="IRB70_004005"
                     /EC_number="2.7.6.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414684.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-amino-4-hydroxy-6-
                     hydroxymethyldihydropteridine diphosphokinase"
                     /protein_id="HBC0633857.1"
                     /translation="MTVAYIAIGSNLASPLEQVNAALKALGDIPESRILAVSSFYRTP
                     PLGPQDQPDYLNAAVALETTLAPEELLNHTQRIELQQGRVRKAERWGPRTLDLDIMLF
                     GNEVINTERLTVPHYDMKNRGFMLWPLFEIAPELVFPDGETLRQILHTR"
     gene            complement(451..1869)
                     /gene="pcnB"
                     /locus_tag="IRB70_004006"
     CDS             complement(451..1869)
                     /gene="pcnB"
                     /locus_tag="IRB70_004006"
                     /EC_number="2.7.7.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000174652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polynucleotide adenylyltransferase PcnB"
                     /protein_id="HBC0633858.1"
                     /translation="MTLPRCTIFTRVANFCRKVLSREESEAEQAVARPQVTVIPREQH
                     AISRKDISENALKVMYRLNKAGYEAWLVGGGVRDLLLGKKPKDFDVTTNATPEQVRKL
                     FRNCRLVGRRFRLAHVMFGPEIIEVATFRGHHEGNVSDRTTSQRGQNGMLLRDNIFGS
                     IEEDAQRRDFTINSLYYSVADFTVRDYVGGMKDLKDGVIRLIGNPETRYREDPVRMLR
                     AVRFAAKLGMRISPETAEPIPRLATLLNDIPPARLFEESLKLLQAGYGYETYKLLCEY
                     HLFQPLFPTITRYFTENGDSPMERIIEQVLKNTDTRIHNDMRVNPAFLFAAMFWYPLL
                     ETAQKIAQESGLTYHDAFALAMNDVLDEACRSLAIPKRLTTLTRDIWQLQLRMSRRQG
                     KRAWKLLEHPKFRAAYDLLALRAEVERNAELQRLVKWWGEFQVSAPPDQKGMLNELDE
                     EPSPRRRTRRPRKRAPRREGTA"
     gene            complement(1908..2834)
                     /gene="gluQRS"
                     /locus_tag="IRB70_004007"
     CDS             complement(1908..2834)
                     /gene="gluQRS"
                     /locus_tag="IRB70_004007"
                     /EC_number="6.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001432381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA glutamyl-Q(34) synthetase GluQRS"
                     /protein_id="HBC0633859.1"
                     /translation="MLPPYFLFKEMTDTHYIGRFAPSPSGELHFGSLIAALGSYLQAR
                     ARQGLWLVRIEDIDPPREVPGAAETILRQLEHYGLHWDGDVLWQSQRHHAYREALAWL
                     HEQGLSYYCTCTRARIQSIGGIYDGHCRDLHHGPDNAAVRIRQQHPVTQFTDLLRGII
                     HADEKLAREDFIIHRRDGLFAYNLAVVVDDHFQGVSEIVRGADLIEPTVRQISLYQLF
                     GWQVPDYIHLPLALNAQGAKLSKQNHAPALPKGDPRPVLIAALHFLGQQVETHWQDFS
                     VEQILQSAVKNWTLTAVPESAIVNSTFSNASC"
     gene            complement(2871..3326)
                     /gene="dksA"
                     /locus_tag="IRB70_004008"
     CDS             complement(2871..3326)
                     /gene="dksA"
                     /locus_tag="IRB70_004008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002209354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase-binding protein DksA"
                     /protein_id="HBC0633860.1"
                     /translation="MQEGQNRKTSSLSILAIAGVEPYQEKPGEEYMNEAQLAHFRRIL
                     EAWRNQLRDEVDRTVTHMQDEAANFPDPVDRAAQEEEFSLELRNRDRERKLIKKIEKT
                     LKKVEDEDFGYCESCGVEIGIRRLEARPTADLCIDCKTLAEIREKQMAG"
     gene            complement(3504..4208)
                     /gene="sfsA"
                     /locus_tag="IRB70_004009"
     CDS             complement(3504..4208)
                     /gene="sfsA"
                     /locus_tag="IRB70_004009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBC0633861.1"
                     /translation="MEFSPPLQRATLIQRYKRFLADVITPDGRELTLHCPNTGAMTGC
                     ATPGDTVWYSTSDNTKRKYPHTWELTQSQSGAFICVNTLWANRLTKEAILNESISELS
                     GYSSLKSEVKYGAERSRIDFMLQADSRPDCYIEVKSVTLAENEQGYFPDAVTERGQKH
                     LRELMSVAAEGQRAVIFFAVLHSAITRFSPARHIDEKYAQLLSEAQQRGVEILAYKAE
                     LSAEGMALKKSLPVTL"
     gene            complement(4223..4753)
                     /gene="thpR"
                     /locus_tag="IRB70_004010"
     CDS             complement(4223..4753)
                     /gene="thpR"
                     /locus_tag="IRB70_004010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414689.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA 2',3'-cyclic phosphodiesterase"
                     /protein_id="HBC0633862.1"
                     /translation="MSEPQRLFFAIDLPAEIREQIIHWRATQFPPEAGRPVAADNLHL
                     TLAFLGEVSAEKEKALSLLAGRIRQPGFTLTLDDAGQWLRSRVVWLGMRQPPRGLIQL
                     ANMLRSQAARSGCFQSNRPFHPHITLLRDASEAVTIPPPGFNWSYTVTEFTLYASSFA
                     RGRTRYTPLKRWALTQ"
     gene            4827..7256
                     /gene="hrpB"
                     /locus_tag="IRB70_004011"
     CDS             4827..7256
                     /gene="hrpB"
                     /locus_tag="IRB70_004011"
                     /EC_number="3.6.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414690.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase HrpB"
                     /protein_id="HBC0633863.1"
                     /translation="MSSLPVAAVLPELLAALDGASQVLLSAPTGAGKSTWLPLQLLAH
                     PGINGKVILLEPRRLAARNVAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLEVVTEG
                     VLTRMIQRDPELSGVGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLD
                     NDRLQQMLPEAPVIISEGRSFPVERRYLPLPAHQRFDEAVAVATAEMLRQESGSLLLF
                     LPGVGEIQRVQEQLASRIGSDVLLCPLYGALSLNDQRKAILPAPQGMRKVVLATNIAE
                     TSLTIEGIRLVVDCAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRLEPGICLH
                     LIAKEQAERAAAQSEPEILQSDLSGLLMELLQWGCSDPAQMSWLDQPPTVNLLAAKRL
                     LRMLGALDGERLSAQGQKMAALGNDPRLAAMLVSAKNDDEAATAAKIAAILEEPPRMG
                     NSDLGVAFSRNQPAWQQRSQQLLKRLNVRGGEADSSLIAPLLARAYADRIARRRGQDG
                     RYQLANGMGAMLDADDALSRHEWLIAPLLLQGSASPDARILLALPVDIDELVQRCPQL
                     VQQSDTVEWDDAQGTLKAWRRLQIGQLMVKVQPLAKPSEDELHQAMLNGIRDKGLSVL
                     NWTAEAEQLRLRLLCAAKWLPEYDWPAVDDESLLATLETWLLPHMTGVHSLRGLKSLD
                     IYQALRGLLDWVMQQRLDSELPAHYTVPTGSRIAIRYHEDNPPALAVRMQEMFGEATN
                     PMIAQGRVPLVLELLSPAQRPLQITRDLSAFWKGAYREVQKEMKGRYPKHVWPDDPAN
                     TAPTRRTKKYS"
     gene            7350..9884
                     /gene="mrcB"
                     /locus_tag="IRB70_004012"
     CDS             7350..9884
                     /gene="mrcB"
                     /locus_tag="IRB70_004012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706097.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glycosyl
                     transferase/transpeptidase"
                     /protein_id="HBC0633864.1"
                     /translation="MAGNDREPIGRKGKPTRPVKQKVSRRRYEDDDDYDDYDDYEDEE
                     PMPRKGKGKGKGRKPRGKRGWLWLLLKLAIVFAVLIAIYGVYLDQKIRSRIDGKVWQL
                     PAAVYGRMVNLEPDMTISKNEMVKLLEATQYRQVSKMTRPGEFTVQANSIEMIRRPFD
                     FPDSKEGQVRARLTFDGDHLATIVNMENNRQFGFFRLDPRLITMISSPNGEQRLFVPR
                     SGFPDLLVDTLLATEDRHFYEHDGISLYSIGRAVLANLTAGRTVQGASTLTQQLVKNL
                     FLSSERSYWRKANEAYMALIMDARYSKDRILELYMNEVYLGQSGDNEIRGFPLASLYY
                     FGRPVEELSLDQQALLVGMVKGASIYNPWRNPKLALERRNLVLRLLQQQQIIDQELYD
                     MLSARPLGVQPRGGVISPQPAFMQLVRQELQAKLGDKVKDLSGVKIFTTFDSVAQDAA
                     EKAAVEGIPALKKQRKLSDLETAIVVVDRFSGEVRAMVGGSEPQFAGYNRAMQARRSI
                     GSLAKPATYLTALSQPKIYRLNTWIADAPIALRQPNGQVWSPQNDDRRYSESGRVMLV
                     DALTRSMNVPTVNLGMALGLPAVTETWIKLGVPKDQLHPVPAMLLGALNLTPIEVAQA
                     FQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLWTMQQVVQRGT
                     GRQLGAKYPNLHLAGKTGTTNNNVDTWFAGIDGSTVTITWVGRDNNQPTKLYGASGAM
                     SIYQRYLANQTPTPLNLVPPEDIADMGVDYDGNFVCSGGMRVLPVWTSDPQSLCQQSE
                     IQQQPSGNPFDQSSQPQQQPQQQPAQQEQKDSDGVAGWIKDMFGSN"
     gene            10104..12293
                     /gene="fhuA"
                     /locus_tag="IRB70_004013"
     CDS             10104..12293
                     /gene="fhuA"
                     /locus_tag="IRB70_004013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_459196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrichrome porin FhuA"
                     /protein_id="HBC0633865.1"
                     /translation="MARSKTAQPKHSLRKIAVVVATAVSGMSVYAQAAVEPKEDTITV
                     TAAPAPQESAWGPAATIAAKHSATATKTDTPIEKTPQSISVVTNEEMQMHQFQSVKEA
                     LGYTPGVTVSSRGASNTYDFVIIRGFSSVGLNQNNYLDGLKLQGNFYNDAVIDPYMLE
                     RVELMRGPTSVLYGKSNPGGIISMVSKRPTTDPLKEIQFKMGTDNLFQTGFDFSDALD
                     DNGEFSYRLTGLARSTNEQQKNSESQRYTIAPSFSWRPDDKTNLTFLSYFQNEPETGY
                     YGWLPKEGTVEPLPNGKRLPTDFNEGASNNTYSRNQKMVGYSFEHGFNDTFTVRQNLR
                     FSEMKTSQKSVYGTGIASDGHTLNRGTVVDNERLQNFSVDTQLESKFATGDVGHTLLT
                     GVDFMRMRNDINASFGSAPSIDLYNKYHPEYFAFGSAEPYQMNESKQTGIYVQDQAEW
                     NKWVFTLGGRYDWSKQATTVRENSYTPTEGYIERNDHQFTWRGGVNYLFDNGISPYFS
                     YSQSFEPSAFDLWSNPRVSYKPSKGEQYEAGVKYVPNDMPVVVTGAVYQLTKTNNLTA
                     DPTNPLAQVPAGEIRARGVELEAKAALNANINLTASYTYTDAEYTKDTNLKGKTPEQV
                     PKHMASLWGDYTFNEGPFSGLTLGTGGRFIGSSYGDPANTFKVGSAAVMDAVVKYDLA
                     RFGMAGSSLAVNVNNLLDREYVASCFQTYGCFWGAERQVVATATFRF"
     gene            12344..13141
                     /gene="fhuC"
                     /locus_tag="IRB70_004014"
     CDS             12344..13141
                     /gene="fhuC"
                     /locus_tag="IRB70_004014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe3+-hydroxamate ABC transporter ATP-binding
                     protein FhuC"
                     /protein_id="HBC0633866.1"
                     /translation="MQEYTNHSDTTFALRNISFRVPGRTLLHPLSLTFPAGKVTGLIG
                     HNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFARKVAYLPQQLPPAEGMTV
                     RELVAIGRYPWHGALGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAM
                     LVAQDSRCLLLDEPTSALDIAHQVDVLALVHRLSQERGLTVIAVLHDINMAARYCDYL
                     VALRGGEMIAQGTPAEIMRGETLEMIYGIPMGILPHPAGAAPVSFVY"
     gene            13141..14031
                     /gene="fhuD"
                     /locus_tag="IRB70_004015"
     CDS             13141..14031
                     /gene="fhuD"
                     /locus_tag="IRB70_004015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter
                     substrate-binding protein FhuD"
                     /protein_id="HBC0633867.1"
                     /translation="MSGLPLISRRRLLTAMALSPLLWQMNTAHAAAIDPNRIVALEWL
                     PVELLLALGIVPYGVADTINYRLWVSEPPLPDSVIDVGLRTEPNLELLTEMKPSFMVW
                     SAGYGPSPEMLARIAPGRGFNFSDGKQPLAMARKSLTEMADLLNLQSAAETHLAHYED
                     FIRSMKPRFVKRGARPLLLTTLIDPRHMLVFGPNSLFQEILDEYGIPNAWQGETNFWG
                     STAVSIDRLAAYKDVDVLCFDHDNSKDMDALMATPLWQAMPFVRAGRFQRVPAVWFYG
                     ATLSAMHFVRILDNAIGGKA"
     gene            14028..16010
                     /gene="fhuB"
                     /locus_tag="IRB70_004016"
     CDS             14028..16010
                     /gene="fhuB"
                     /locus_tag="IRB70_004016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe(3+)-hydroxamate ABC transporter permease
                     FhuB"
                     /protein_id="HBC0633868.1"
                     /translation="MSKRIALFPVLLLVLLVVAAAALTWMNFSQALPRSQWAQAAWSP
                     DIDVIEQMIFHYSLLPRLAISLLVGAGLGMVGVLFQQVLRNPLAEPTTLGVATGAQLG
                     ITVTTLWAIPGAMASQFAALAGACVVGLIVFGVAWGKRLSPVTLILAGLVVSLYCGAI
                     NQLLVIFHHDQLQSMFLWSTGTLTQTDWGGVERLWPQLLGGVMLTLLLLRPLTLMGLD
                     DGVARNLGLALSLARLAALSLAIVISALLVNAVGIIGFIGLFAPLLAKMLGARRLLPR
                     LMLASLIGALILWLSDQIILWLTRVWMEVSTGSVTALIGAPLLLWLLPRLRSISAPDM
                     KVNDRVATERQHVLAFALAGGVLLLMAVVVALSFGRDAHGWTWASGALLEDLMPWRWP
                     RIMAALFAGVMLAVAGCIIQRLTGNPMASPEVLGISSGAAFGVVLMLFLVPGNAFGWL
                     LPAGSLGAAVTLLIIMIAAGRGGFSPHRMLLAGMALSTAFTMLLMMLQASGDPRMAQV
                     LTWISGSTYNATEAQVWRTGIVMVILLAITPLCRRWLTILPLGGDTARAVGMALTPTR
                     IALLLLAACLTATATMTIGPLSFVGLMAPHIARMMGFRRTMPHIMISALVGGLLLVFA
                     DWCGRMVLFPFQIPAGLLSTFIGAPYFIYLLRKQSR"
BASE COUNT         3568 a         4053 c         4617 g         3859 t
ORIGIN      
        1 ctcttgtatg taagatttga cgcaacgtct ccccatcagg aaacactaac tccggcgcaa
       61 tttcaaacag tggccacagc ataaagccac gatttttcat atcgtagtgc ggaacggtca
      121 gacgttcggt atttattact tcattaccaa acagcatgat gtcgagatcc agcgtgcgtg
      181 gtccccagcg ttccgcttta cggacgcgac cttgctgcaa ttcgatacgc tgtgtgtgat
      241 tgagtagctc ttcaggggca agagtggttt ccagcgcgac ggcggcattt aagtaatcgg
      301 gttgatcttg cggccccagc ggtggggtgc ggtaaaacga agaaacagca agaatgcggc
      361 tttctggaat atcgcctaat gctttcaggg cagcattgac ctgctccagc ggagaggcca
      421 gattgctgcc tatggcaata tacgccactg tcatgcggta ccctcacgac gcggtgcgcg
      481 tttgcgtgga cgacgagtac gacgacgcgg tgacggttct tcatccagtt cgttaagcat
      541 ccctttttgg tctggcggcg cggaaacctg gaactcaccc caccatttca ccagacgttg
      601 cagttcagcg ttacgctcaa cttcggctcg taaggccaac aggtcgtatg ccgcacggaa
      661 cttaggatgc tccagcagtt tccatgcgcg ttttccctga cgacgggaca tacgcaactg
      721 caactgccag atatcgcgag ttagcgtagt cagacgtttc gggatcgcca gtgaacggca
      781 ggcttcgtcc agcacgtcgt tcatcgccag tgcgaaagcg tcgtgatagg tcaggccgct
      841 ctcctgagca attttctgtg ccgtctccag cagtggatac cagaacatgg cggcaaacag
      901 gaacgccggg ttcacgcgca tatcgttatg gatacgcgta tcggtattct tcagcacctg
      961 ttcaatgatc cgctccatcg ggctgtcgcc attttccgtg aagtagcggg taatggtcgg
     1021 gaacagcggc tggaacagat gatattcaca cagcagctta taagtttcgt aaccgtagcc
     1081 cgcttgcaac agtttcagcg attcttcaaa cagacgtgcc ggtgggatat cgttcagtaa
     1141 ggttgccagg cgtgggatcg gctcggcggt ttccgggctg atgcgcatgc ccaatttggc
     1201 ggcaaaacga accgcgcgaa gcatccgtac cggatcttca cggtagcgcg tttccgggtt
     1261 accaatcaga cggataacgc cgtctttcag atccttcatg ccgccaacgt aatcacggac
     1321 ggtaaaatct gccacgctgt aatacaggct gttgatagtg aaatcgcggc gctgggcgtc
     1381 ttcttcgatg gagccgaaaa tgttgtcgcg cagcaacata ccgttttgcc cgcgttggga
     1441 ggtcgtgcgg tcgctgacgt taccttcgtg atgtccacgg aaggtcgcaa cttcgataat
     1501 ctccgggcca aacatcacat gagccagacg gaaacggcga cccaccaggc ggcagttacg
     1561 gaacagtttg cgcacctgct ctggcgtggc gttggtggtc acgtcaaaat ctttcggctt
     1621 tttgccaagt aacaggtcgc gcacgccgcc gccaaccagc caggcttcgt atcccgcttt
     1681 attgagcctg tacattacct tcagggcatt ttcactgata tctttgcggg aaatagcatg
     1741 ctgctcacgc gggatcaccg tcacctgtgg acgggcgact gcctgttcag cctcgctttc
     1801 ctcgcggctt agcaccttgc ggcaaaaatt agcgactcgg gtaaaaatag tacacctcgg
     1861 tagtgtcaaa catcattcag gacaaaaaaa tagcggctaa tcatagctca gcatgacgca
     1921 tttgagaatg ttgaatttac aattgccgac tcaggcacgg cagtcagcgt ccagtttttg
     1981 acggctgact gaaggatttg ctcgacgctg aaatcctgcc agtgtgtttc tacctgctga
     2041 cccagaaaat gaagtgccgc gattaacacc gggcgcggat cgcctttcgg caacgcaggc
     2101 gcatgattct gcttggaaag tttagcgcct tgtgcgttta gcgccagcgg taaatgaatg
     2161 taatctggca cctgccagcc aaaaagctgg tacagcgaga tttgccgcac tgtcggttcg
     2221 atcaaatctg ccccgcggac aatttcgctc acgccctgga agtgatcatc caccaccacc
     2281 gccaggttat aggcaaacaa accatcacgg cgatgaataa taaaatcttc ccgtgccagt
     2341 ttttcgtcgg cgtgaataat gcctcgcagc aggtcagtaa actgggtgac cggatgctgc
     2401 tggcggatac gtactgcggc gttgtctggt ccatgatgca aatcccggca atgaccgtcg
     2461 taaataccgc caatgctttg aatacgcgca cgcgtgcagg tgcagtaata acttagtcct
     2521 tgctcatgta accaggcgag tgcttcgcga taggcgtggt gacgttgcga ttgccagaga
     2581 acgtcgccgt cccagtgcag gccgtaatgt tccagctggc gcaggatagt ctctgcggca
     2641 ccgggaactt cacgaggcgg gtcgatatct tctatgcgta ccagccagag accttgccgg
     2701 gcgcgagcct gtaaatagct gccaagcgcg gcaatcagag agccaaaatg aagctcgccg
     2761 gaaggagagg gggcgaagcg accaatatag tgtgtgtctg tcatctcttt gaacaaaaaa
     2821 taaggcggga gcatttcccg cctgtggtaa acgtgatgga acggctgtaa ttagccagcc
     2881 atttgttttt cgcgaatttc agccagcgtt ttgcagtcga tgcacagatc ggctgtcggg
     2941 cgcgcttcca gacggcgaat accaatttca acaccgcagg actcgcagta gccgaaatct
     3001 tcgtcttcca cttttttcag cgtcttctcg atctttttga tcagcttacg ctcgcgatcg
     3061 cggttacgca gttcgaggct gaactcttct tcctgggctg cacggtctac cgggtccggg
     3121 aagttggctg cttcatcctg catatgtgta acggtgcgat cgacttcatc cctgagttga
     3181 ttacgccatg cttccagaat acgacggaag tgcgccagct gggcttcatt catatactct
     3241 tcgcccggct tctcctgata tggctccacc ccagcgatgg cgagaatact cagggacgat
     3301 gttttacggt tttgcccttc ttgcatgttg cttctcctta acacgcacta tcgatcccca
     3361 tgttcggggg aaaaatgagg ccgctataaa tagcagatgc ttttccggat agcaattatc
     3421 taaacgtaac acttgacaac tgtgtgagga aaagcgtatt tgcgcacgcg accagaatgt
     3481 aaattaacca gttacttact ctactacaat gtaaccggta gtgatttttt aagagccatg
     3541 ccttcggcag aaagttccgc tttgtaagcc agaatttcta cccccctctg ttgagcttct
     3601 gacaatagtt gcgcgtattt ctcatcgatg tggcgcgcgg gtgaaaaccg tgtaatggct
     3661 gaatgcagca cggcgaaaaa gataaccgca cgctggcctt cagccgctac gctcatcaac
     3721 tcccgaaggt gtttctgacc tcgttcagtg accgcatcgg gaaaatatcc ctgttcgttc
     3781 tccgctaacg taaccgattt cacttcaata tagcagtctg gacgcgaatc cgcctgcaac
     3841 ataaagtcaa tacggctgcg ttctgcgccg tattttactt cgcttttcag cgagctatag
     3901 cctgacagtt ctgaaattga ttcattaagg atagcctctt tcgtcagcct gttagcccaa
     3961 agcgtattga cgcaaataaa tgcgccgctc tggctttgag ttaattccca ggtgtgtggg
     4021 tatttccgtt tggtgttgtc tgaagttgaa taccagacgg tatcgccagg cgttgcacaa
     4081 ccggtcatcg cacccgtatt cgggcagtgt agcgttaatt cgcgaccatc gggtgtgatc
     4141 acatcggcta aaaaacgttt gtaacgctga attagcgtcg cgcgctgtag agggggagaa
     4201 aattccattg caacaatcct tgttattgcg ttagcgccca gcgttttagc ggcgtgtagc
     4261 gtgtgcgtcc acgggcaaac gaggaggcgt aaagggtgaa ctccgtcacc gtatacgacc
     4321 agttaaaacc tggcggcggg attgtcaccg cctcgctggc gtcgcgcaat aaggtaatat
     4381 gtggatgaaa cggacgattg ctttgaaaac aaccgctgcg ggcagcctgt gagcggagca
     4441 tattcgccag ctggattaag ccgcgtggcg gctgtcgcat ccctaaccac accacacgcg
     4501 aacgcagcca ttgaccggcg tcatcaagcg tgagtgtgaa accaggttga cgaatccgtc
     4561 cggctaaaag agaaagcgcc ttctctttct ctgcgctcac ttcgcctaaa aatgccagag
     4621 tcagatgcaa attatcggcg gcaaccggac gtcccgcctc aggtgggaac tgtgtggcgc
     4681 gccagtggat aatctgttcg cggatttctg caggtaagtc gatagcaaag aacagccgtt
     4741 gcggttcaga catgtgaggc actcggttat gaattaccgc gatgctacaa tgtggcgcga
     4801 agaatgttaa ccctctggag cgttttgtgt cgtcgttgcc cgttgctgcc gtcttacctg
     4861 agttacttgc tgccctcgat ggtgcatcgc aggtgttatt aagtgcgccg accggggccg
     4921 ggaaatcaac ctggctgccg ctgcaactgc tggcgcatcc aggcattaac gggaaagtta
     4981 tcctgctgga gccgcgtcgt ctggcggcgc gtaacgttgc gcaacgactg gcggagctgc
     5041 ttaacgaaaa gccaggcgat accgttggct accggatgcg tgcgcaaaac tgcgtcgggc
     5101 cgaatacccg cctggaagtg gttaccgaag gcgtgctgac gcggatgatc cagcgtgacc
     5161 cggaactgag cggtgttgga ttggtgatcc ttgatgaatt tcatgagcgc agcttgcagg
     5221 cggatttggc gttggcgctg ttactcgatg tgcaacaagg tctgcgtgat gaccttaaac
     5281 tgctgattat gtcggctacg ctggacaacg accgcttgca gcaaatgctg ccagaagcgc
     5341 ccgtcatcat ctcagaaggg cgctcgtttc cggttgaacg ccgttattta ccgctgcccg
     5401 cgcatcagcg ttttgacgaa gccgttgcgg tagccaccgc cgaaatgctg cgtcaggaaa
     5461 gcggatcatt actgttattt ttacctggcg tcggagaaat tcagcgtgtg caggaacaac
     5521 tggcttcgcg catcggcagt gatgtgttgc tctgcccgct gtatggcgcg ttgtcgctga
     5581 acgatcagcg aaaagcgatc ctcccggcac cgcaagggat gcgcaaagtg gtgctggcga
     5641 ccaatattgc tgaaaccagt ttaaccattg aaggtattcg tctggtggtg gattgtgccc
     5701 aggagagggt ggcgcgtttt gatccgcgta cagggcttac gcggttgatt actcaacgcg
     5761 ttagtcaggc gtcgatgacg caacgtgccg ggcgtgccgg gcgtctggag ccgggtatct
     5821 gcctgcattt aatcgccaaa gaacaagccg aacgcgccgc ggcgcaaagt gaaccggaaa
     5881 tattacaaag cgatctctcc ggtttgctga tggaattact gcaatgggga tgcagcgatc
     5941 ctgcgcagat gagctggctg gatcaaccgc caacggtgaa tctactggcc gcgaaacgcc
     6001 tgttacggat gctgggggcg ctggacggtg aacggcttag tgcgcaaggg caaaaaatgg
     6061 cagcgctggg taacgatccg cgtttagcgg caatgctggt tagcgcgaag aacgacgacg
     6121 aagctgctac cgcggcaaaa attgccgcca ttctcgaaga gccgccacgg atgggcaata
     6181 gtgacctggg cgtggcgttt tcgcgcaatc aacccgcctg gcagcaacgt agtcagcaac
     6241 tgttaaaacg cttaaacgta cgcggcggtg aggcagacag ttcgcttatc gcgccgctac
     6301 ttgccagagc gtatgccgat cgcattgctc gtcgccgtgg gcaagatgga cgctatcaac
     6361 tggcgaacgg catgggggcg atgctcgatg ccgacgatgc gctaagccgc cacgaatggt
     6421 tgatcgcacc gttattattg cagggcagcg cctcgccgga tgcgcggatt ttactggcgc
     6481 taccggtcga tattgatgag ttagtacaac gctgcccgca gctggtacag caatcggaca
     6541 ccgtggagtg ggatgacgcg caaggtacgc tgaaagcctg gcgtcggctg caaatcggtc
     6601 agttgatggt gaaagtgcag ccactggcga aaccctcgga agacgagttg catcaggcga
     6661 tgcttaacgg cattcgtgat aaaggtttaa gcgtgctcaa ctggacggcg gaagcggaac
     6721 agttacgctt gcgtttgtta tgcgccgcaa agtggttgcc ggaatatgac tggccagcgg
     6781 ttgatgatga gagtttgttg gcgacgctgg aaacgtggct actgccgcat atgacaggcg
     6841 tacattcgct acgcggcttg aaatcactcg atatttatca ggcactgcgt ggattacttg
     6901 attgggtaat gcagcaacgt ctggatagtg aattgcctgc gcattacact gtgccgacgg
     6961 gaagccggat cgccattcgt tatcatgaag ataacccgcc cgcgctggcg gtgagaatgc
     7021 aggagatgtt tggcgaggcc accaatccga tgatcgccca ggggcgcgtg ccgctggtgc
     7081 tggagttgct ttcccctgcc caaaggccgc tgcaaatcac gcgtgatttg agcgccttct
     7141 ggaaaggagc gtaccgtgag gtgcaaaaag agatgaaagg gcgttatccc aaacatgtct
     7201 ggccggacga cccggcaaac accgcaccga cgcgacgaac gaaaaagtat tcgtgaagac
     7261 caaagcaaat ttgagagata tcttcttctg tcttgcaaca gaagaacaga aaatcgggct
     7321 tttgcgcctg aatattgcgg agaaaaagca tggccgggaa tgaccgcgag ccaattggac
     7381 gcaaagggaa accgacgcgt ccggtcaaac aaaaggtaag ccgtcgtcgt tacgaagatg
     7441 acgatgatta cgacgattat gatgactatg aggatgaaga accgatgccg cgcaaaggta
     7501 agggcaaagg caaagggcgt aagcctcgtg gcaaacgcgg ctggctatgg ctgctgctaa
     7561 aactggctat cgtttttgcc gtgctgatcg ccatttacgg cgtttatctc gatcaaaaaa
     7621 ttcgcagccg tattgatggc aaggtctggc aattgcccgc ggcagtttat ggccgaatgg
     7681 tcaaccttga gccagacatg accatcagca agaacgagat ggtgaagctg ctggaggcga
     7741 cccagtatcg tcaggtgtcg aaaatgaccc gtcctggcga atttaccgtg caggccaaca
     7801 gcattgagat gatccgccgt ccgtttgatt tcccggacag taaagaaggg caggtgcgtg
     7861 cacgtctgac ctttgatggc gatcatctgg cgacgatcgt caatatggag aacaaccgtc
     7921 agttcggttt cttccgtctt gatccgcgcc tgatcactat gatctcttca ccaaacggtg
     7981 agcaacgtct gtttgtgccg cgcagtggtt tcccggatct gctggtggat actttgctgg
     8041 caacagaaga ccgtcatttt tacgagcatg atgggatcag tctctactcc atcggacgtg
     8101 cggtgctggc aaacctgacc gccggacgca cggtgcaggg ggcgagtacg ctgacgcaac
     8161 agctggtgaa aaacctgttc ctctccagcg agcgttctta ctggcgtaaa gcgaacgaag
     8221 cctacatggc gctgatcatg gacgcgcgtt acagcaaaga ccgtattctt gagctgtata
     8281 tgaacgaggt gtatctcggt cagagcggcg acaacgaaat ccgcggcttc ccgctggcga
     8341 gcttgtatta ctttggtcgc ccggtagaag aattgagcct cgatcagcag gcgctgttgg
     8401 tgggtatggt gaaaggggcg tccatctaca acccgtggcg taacccgaaa ctggcgctgg
     8461 agcgacgtaa cctggtgcta cgtctgctgc aacagcaaca gattattgat caagaactct
     8521 atgacatgtt gagtgcacgt ccgctgggtg ttcagccgcg cggtggggtg atctctcctc
     8581 agccagcctt tatgcaactg gtgcgtcagg agctgcaggc gaaattaggc gataaggtaa
     8641 aagatctctc cggcgtgaag atcttcacta cctttgactc ggtggcccag gacgcggcag
     8701 aaaaagccgc cgtggaaggc attccggcac tgaagaaaca gcgtaagttg agcgatctgg
     8761 aaaccgcgat tgtggtcgtc gaccgcttta gtggtgaagt tcgtgcgatg gtcggtggtt
     8821 ctgagccgca gtttgcgggc tacaaccgtg cgatgcaggc gcgtcgttcg attggttctc
     8881 ttgcaaaacc agcgacttat ctgacggcct taagccagcc gaaaatctat cgcctgaaca
     8941 cgtggattgc cgatgcgcca atcgcgctgc gtcagccgaa tggccaggtc tggtcaccgc
     9001 agaacgatga ccgtcgttat agcgaaagtg gcagagtgat gctggtggat gcgttgaccc
     9061 gttcgatgaa cgtgccgacg gtaaatctgg ggatggcgct ggggctgcct gcggttacgg
     9121 agacctggat taaactgggc gtaccgaaag atcagctgca tccggttccg gcgatgctgc
     9181 tgggggcgtt gaacttaacg ccaatcgaag tggcgcaggc attccagact atcgccagcg
     9241 gcggtaaccg tgcaccgctt tctgcgctgc gttcggtaat tgcggaagat ggcaaagtgc
     9301 tgtatcagag cttcccgcag gcggaacgcg cggttccggc gcaggcggcg tatctgacac
     9361 tatggaccat gcagcaggtg gtacaacgtg gtacggggcg tcagcttggg gcgaaatacc
     9421 cgaacctgca tctggcaggg aaaacaggga ctaccaacaa taacgtagat acctggtttg
     9481 cgggcattga cggcagcacg gtgaccatca cctgggtagg ccgtgataac aaccagccga
     9541 ccaaactgta tggagccagc ggggcaatgt cgatttatca gcgttatctg gctaaccaga
     9601 cgccaacacc gctgaatctt gttccgccag aagatattgc agatatgggc gtggactacg
     9661 acggcaactt tgtttgcagc ggtggcatgc gtgtcttgcc ggtctggacc agcgatccgc
     9721 aatcgctgtg ccagcagagt gagattcagc agcaaccgtc aggcaatccg tttgatcagt
     9781 cttctcagcc gcagcaacaa ccgcaacagc aacctgctca gcaagagcag aaagacagcg
     9841 acggtgtagc tggttggatc aaggatatgt ttggtagtaa ttaacgtcta agcgtgacat
     9901 accggatggc gagttgccat ccggtaaaat aacatcccac ctaaagtatt aaccctttct
     9961 tttcatctgg ttgtttatta acccttcagg aacgctcaga ttgcgtaccg cttgcgaacc
    10021 cgccagcgtt tcgaatatta tcttatcttt ataataatca ttctcgttta cgttatcatt
    10081 cactttacat cagagatata ccaatggcgc gttccaaaac tgctcagcca aaacactcac
    10141 tgcgtaaaat cgcagttgta gtagccacag cggttagcgg catgtctgtt tatgcacagg
    10201 cagcggttga accgaaagaa gacactatca ccgttaccgc tgcacctgcg ccgcaagaaa
    10261 gcgcatgggg gccagctgca actattgcgg cgaagcactc tgctactgcg actaaaacgg
    10321 atacaccaat tgaaaaaacg ccgcagtcta tttcggttgt gacaaatgaa gagatgcaga
    10381 tgcatcaatt tcagtctgta aaagaagcat taggttatac acctggcgtt acagttagca
    10441 gtcgtggtgc ttctaataca tatgattttg ttatcattcg tggtttctca tctgttggcc
    10501 tgaatcaaaa taactacctt gatggactaa aacttcaggg caacttttat aacgatgctg
    10561 tgattgatcc ttacatgctc gagagggttg aactgatgcg tgggccgacg tctgttctct
    10621 atggaaaaag taatcctggt gggattattt ctatggtgag taagcgcccg accactgacc
    10681 ccctgaaaga aattcagttt aaaatgggga cggataatct gtttcagacc ggattcgatt
    10741 tcagtgatgc gctggatgat aacggtgagt tctcctaccg tttgactggc ctcgctcgct
    10801 caacaaacga acagcagaaa aactctgaat ctcagcgtta taccattgct ccatcattct
    10861 catggcggcc ggacgacaaa accaatttaa ctttcctgtc ctatttccag aatgaaccag
    10921 aaacgggtta ttacggttgg ttgccgaaag aggggaccgt tgagccattg cctaatggta
    10981 agcgtctacc gactgacttc aatgaaggtg cgtcgaataa tacatactcc cgtaaccaga
    11041 aaatggtggg atatagtttt gaacatggtt ttaatgacac cttcaccgtg cgtcagaatc
    11101 tgcgtttcag tgaaatgaaa acctcacaga aaagtgttta tggcacaggg attgccagcg
    11161 atggtcatac cctaaaccgc gggacagtgg tggataatga gcgtctacaa aactttagcg
    11221 ttgataccca acttgaaagt aagtttgcta caggtgacgt cgggcatact ttgctgacag
    11281 gggtagactt catgcgtatg cgcaatgata tcaatgccag ctttggatct gcaccatcca
    11341 tcgatcttta taacaaatac catcctgaat actttgcatt tggtagcgca gagccatacc
    11401 agatgaatga aagcaaacaa acaggtattt atgttcagga tcaggcggaa tggaataaat
    11461 gggtattcac tctggggggg cgctacgatt ggtctaagca agcgaccact gttcgtgaaa
    11521 actcttatac gccgactgaa ggttatattg agcgcaatga tcatcagttc acctggcgcg
    11581 gtggtgtaaa ttacttattc gataatggta tttcacctta ctttagctat agccagtcct
    11641 ttgaaccgag tgctttcgat ctgtggagca acccgcgcgt ttcctataag ccatcgaaag
    11701 gtgaacagta tgaagctggc gtaaaatatg ttccgaatga tatgccggtc gttgttacgg
    11761 gcgcagtcta tcaattgacg aaaacaaata acctgacagc agacccaaca aacccattag
    11821 cgcaagtccc ggcaggtgag attcgcgctc gtggtgtgga acttgaagca aaagcggcgt
    11881 taaatgccaa tattaacttg acggcttctt atacctacac cgatgcggaa tacaccaaag
    11941 acaccaatct caaaggtaaa actccagaac aagtaccgaa gcatatggca tctctctggg
    12001 gggattatac cttcaatgaa gggccgtttt ctggtttaac attgggaaca ggtggtcgtt
    12061 ttattggttc cagctatggt gatccggcga acacttttaa agtgggtagc gcagctgtaa
    12121 tggatgctgt tgtaaaatat gatctggcac gctttggtat ggcgggatcc agccttgctg
    12181 tgaacgtcaa caatttgctc gatcgtgagt atgttgccag ttgcttccag acctatggct
    12241 gcttctgggg cgcagaacgt caggtcgttg caaccgcaac cttccgtttc taatttctct
    12301 tttggggcac ggatttccgt gcccgtttca caagttggct gttatgcagg aatacacgaa
    12361 tcattccgat accacttttg cactgcgtaa tatctccttt cgtgtgcccg ggcgcacgct
    12421 tttgcatccg ctgtcgttaa cctttcctgc cgggaaagtg accggtctga ttggtcacaa
    12481 cggttctggt aaatccactc tgctcaaaat gcttggccgt catcagccgc cgtcggaagg
    12541 ggagattctt cttgatgccc agccgctgga aagctggagt agcaaagcgt ttgcccgcaa
    12601 agtggcttat ttgccgcagc agcttcctcc ggcagaaggg atgacggtgc gtgaactggt
    12661 ggcgattggt cgttacccgt ggcatggcgc actagggcgc tttggtgcgg cagatcgcga
    12721 aaaggtcgag gaagctatct cgctggttgg cttaaaaccg ctggcgcatc ggctggtcga
    12781 tagtctctct ggcggcgaac gtcagcgggc gtggatcgcc atgctggtgg cgcaggatag
    12841 ccgttgtctg ttgctcgacg aaccgacctc ggcgctggat atcgcccacc aggttgatgt
    12901 gctggcgctg gtgcatcgtt taagtcagga gcgtggcctg acggtcattg ccgtgctgca
    12961 cgatatcaat atggctgcgc gttactgtga ttatctggtc gccctgcgcg gcggtgaaat
    13021 gattgctcag ggaacgcctg cggaaattat gcgcggcgaa accctcgaaa tgatttatgg
    13081 catcccgatg ggtattttgc cgcatccggc gggtgctgca cctgtgagtt ttgtttattg
    13141 atgagcggct tacctcttat ttcgcgccgt cgactgttaa cggcgatggc gctttctccg
    13201 ttgttatggc agatgaatac cgcccacgcg gcggctattg atcccaatcg tattgtggcg
    13261 ctggagtggt tgccggtgga attactgctg gcgctcggca tcgtgcctta cggcgtggcg
    13321 gataccatca actatcgcct gtgggtcagc gaaccgccat tgccggactc agtgattgac
    13381 gttggtttgc gtacagaacc taaccttgaa ctgctgaccg aaatgaaacc atcgtttatg
    13441 gtctggtcgg caggatatgg cccttcacca gaaatgctgg cacgtattgc gccgggtcgc
    13501 ggatttaact tcagtgacgg caaacagccg ctggcgatgg cgcgtaaatc actgacggaa
    13561 atggcagatt tacttaacct gcaaagcgca gcagaaacgc atttagcgca ctatgaagac
    13621 tttatccgca gcatgaaacc ccgctttgtg aagcgtggtg cacgcccgtt attgctgacg
    13681 acacttatcg atccgcgcca tatgttggtc ttcggtccaa acagcctgtt ccaggaaatt
    13741 cttgatgagt acggcatccc aaatgcctgg caaggggaaa ccaacttttg gggcagtacc
    13801 gccgtcagta tcgatcgtct ggcagcgtat aaagacgttg atgtgctctg ttttgatcac
    13861 gacaacagca aagacatgga tgcgctaatg gcaaccccgc tgtggcaggc catgccgttt
    13921 gtccgcgccg gacgctttca gcgcgttccg gcggtctggt tctatggtgc gacgctttct
    13981 gcaatgcact ttgtgcgtat tctggataac gccatcggag gtaaagcgtg agtaaacgaa
    14041 ttgcgctttt tccggtgtta ttgctggtgc tgctggtggt tgctgctgcg gcgttgacct
    14101 ggatgaactt ctcgcaggcg ctgccgcgca gccagtgggc gcaggccgcc tggtcgccgg
    14161 atattgacgt catcgagcag atgatttttc actacagctt gttgccgcgt ctggcgattt
    14221 cgctgctggt gggcgcgggc ctggggatgg tgggcgtgct gtttcagcaa gtgctgcgta
    14281 acccgctggc ggaaccgacg acgttgggtg ttgcaacagg cgcgcaactg gggattaccg
    14341 tcaccacgct ctgggcgatc ccaggtgcta tggcgagcca gtttgctgcg ctggcagggg
    14401 cttgtgttgt tggcttaatc gtctttggcg tcgcgtgggg gaaacggctt tcgccggtaa
    14461 cgctgatcct cgcggggctg gtagtgagcc tttattgcgg cgcaatcaat cagttactgg
    14521 ttatcttcca tcatgaccaa ctgcaaagca tgttcctgtg gagcaccgga acgctgacgc
    14581 aaaccgactg gggcggcgtt gagcgtttat ggccgcagct gctgggcggc gtgatgctga
    14641 cgttattgct acttcgcccg ttaaccctga tggggcttga tgatggcgtg gcgcgcaatc
    14701 tcgggctggc cttgtcgctc gcgcgtctgg cggcgttgtc gctggcgatt gtcatcagtg
    14761 cgctgctggt gaacgcggtg gggattatcg gctttatcgg gttgttcgcg ccgctgctgg
    14821 caaaaatgct gggggcgcgg cgtctgctgc cacggttaat gctggcgtcg ctgattggtg
    14881 cgttaattct gtggctttct gatcaaatca tcctctggct gactcgcgtg tggatggaag
    14941 tttccaccgg ttcggtcact gcgttgatcg gtgcgccgct gttactgtgg ttgctgccgc
    15001 gtttacgcag cattagcgcg ccggatatga aggtgaacga tcgtgtcgcg actgaacgcc
    15061 aacacgtgct ggcgtttgcc ctcgcgggcg gcgtgctgct gttgatggct gtggtggtgg
    15121 cgctgtcgtt tggtcgtgat gcgcacggct ggacgtgggc gagcggggcg ttgctcgagg
    15181 atttgatgcc ctggcgctgg ccgcgaatta tggcggcgct gtttgctggc gtcatgctgg
    15241 cggtggcggg ctgtattatt cagcggctga ccggaaaccc gatggcaagc ccggaagtgc
    15301 tggggattag ctccggcgcg gcgtttggcg tggtgttaat gctgtttctg gtgccgggta
    15361 atgcctttgg ctggctgtta cccgcaggca gtctcggggc ggcggtgacg ctgttgatca
    15421 ttatgatcgc cgccggacgc ggtggatttt ccccacaccg catgttactg gcggggatgg
    15481 cgttaagtac cgcgttcacg atgcttttga tgatgttgca ggcaagtggt gacccgcgaa
    15541 tggcgcaagt tctgacctgg atttccggtt cgacctacaa cgcgaccgag gcgcaggtct
    15601 ggcgcacggg aattgtgatg gtaattttgc tggcgattac cccgctgtgc cgccgctggc
    15661 tgaccatttt accgctgggc ggtgataccg cacgagccgt ggggatggcg ctgacgccga
    15721 cgcgaattgc gctgctgctg ttagcggctt gcctgacagc gactgcgaca atgaccattg
    15781 gaccgttgag ttttgttggt ttaatggcac cgcatattgc gcggatgatg ggctttcgac
    15841 ggacgatgcc gcatattatg atttcggcgc tggtgggtgg tttactgctg gtgttcgctg
    15901 actggtgtgg gcggatggtg ctgtttccat tccagatccc agcggggctg ctgtcgacct
    15961 ttatcggcgc gccgtatttt atctatttgt tgagaaagca gagccgttaa tttttccata
    16021 taacggccct taactcctgg atggataaag cttttacgcg gcaacggatg cccgatgcga
    16081 cgctgtggcg tcttatc
//
LOCUS       DADXDL010000104        16008 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.104, whole genome shotgun sequence.
ACCESSION   DADXDL010000104 DADXDL010000000
VERSION     DADXDL010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 16008)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16008)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16008
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.104"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(10..906)
                     /gene="yhaJ"
                     /locus_tag="IRB70_004017"
     CDS             complement(10..906)
                     /gene="yhaJ"
                     /locus_tag="IRB70_004017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator YhaJ"
                     /protein_id="HBC0633869.1"
                     /translation="MAKERALTLEALRVMDAIDRRGSFAAAADELGRVPSALSYTMQK
                     LEEELDVVLFDRSGHRTKFTNVGRMLLERGRVLLEAADKLTTDAEALARGWETHLTIV
                     TEALVPTPAFFPLIDKLAVKANTQLAIITEVLAGAWERLEQGRADIVIAPDMHFRSSS
                     EINSRKLYTLMNVYVAAPDHPIHQEPEPLSEVTRVKYRGIAVADTARERPVLTVQLLD
                     KQPRLTVSTIEDKRQALLAGLGVATMPYPMVEKDIAEGRLRVVSPESTSEIDIIMAWR
                     RDSMGEAKSWCLREIPKLFSGK"
     gene            1011..1712
                     /locus_tag="IRB70_004018"
     CDS             1011..1712
                     /locus_tag="IRB70_004018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pirin family protein"
                     /protein_id="HBC0633870.1"
                     /translation="MITTRTARQCGQADYGWLQARYTFSFGHYFDPKLLGYASLRVLN
                     QEVLAPGAAFQPRTYPKVDILNVILDGEAEYRDSEGNHVQASAGEVLLLSTQPGVSYS
                     EHNLSKDKSLTRMQLWLDACPQRENPLIQKLALNMSKQQLIASPEGGMGSLQLRQQVW
                     LHHIVLDKGESANFQLHGPRAYLQSIHGKFHALTHHEEKAALTCGDGAFIRDEANITL
                     VADSPLRALLIDLPV"
     gene            1735..1899
                     /locus_tag="IRB70_004019"
     CDS             1735..1899
                     /locus_tag="IRB70_004019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312016.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633871.1"
                     /translation="MSKKSAKKRQPVKPVVAKEPSRTAKNFGYEEMLSELEAIVADAE
                     TRLAEDEATA"
     gene            complement(2032..3342)
                     /locus_tag="IRB70_004020"
     CDS             complement(2032..3342)
                     /locus_tag="IRB70_004020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine dehydratase subunit alpha family protein"
                     /protein_id="HBC0633872.1"
                     /translation="MFDSTLNPLWQRYILAVQEEVKPALGCTEPISLALAAAVAAAEL
                     EGPVERVEAWVSPNLMKNGLGVTVPGTGMVGLPIAAALGALGGNANAGLEVLKDATAQ
                     AIADAKALLAAGKVSVKIQEPCDEILFSRAKVWNGEKWACVTIVGGHTNIVHIETHNG
                     VVFTQQACVTEGEQESPLTVLSRTTLAEILKFVNEVPFAAIRFILDSAKLNCALSQEG
                     LSGNWGLHIGATLEKQCARGLLAKDLSSSIVIRTSAASDARMGGATLPAMSNSGSGNQ
                     GITATMPVVVVAEHFGADDERLARALMLSHLSAIYIHNQLPRLSALCAATTAAMGAAA
                     GMAWLVDGRYETISMAISSMIGDVSGMICDGASNSCAMKVSTSASAAWKAVLMALDDT
                     AVTGNEGIVAHDVEQSIANLCALASHSMQQTDRQIIEIMASKAR"
     gene            complement(3370..4701)
                     /locus_tag="IRB70_004021"
     CDS             complement(3370..4701)
                     /locus_tag="IRB70_004021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026203.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAAAP family serine/threonine permease"
                     /protein_id="HBC0633873.1"
                     /translation="MEIASNKGVIADASTPAGRAGMSESEWREAIKFDSTDTGWVIMS
                     IGMAIGAGIVFLPVQVGLMGLWVFLLSSVIGYPAMYLFQRLFINTLAESPECKDYPSV
                     ISGYLGKNWGILLGALYFVMLVIWMFVYSTAITNDSASYLHTFGVTEGLLSDSPFYGL
                     VLICILVAISSRGEKLLFKISTGMVLTKLLVVAALGVSMVGMWHLYNVGSLPPLGLLV
                     KNAIITLPFTLTSILFIQTLSPMVISYRSREKSIEVARHKALRAMNIAFGILFVTVFF
                     YAVSFTLAMGHDEAVKAYEQNISALAIAAQFISGDGAAWVKVVSVILNIFAVMTAFFG
                     VYLGFREATQGIVMNILRRKMPAEKINENLVQRGIMIFAILLAWSAIVLNAPVLSFTS
                     ICSPIFGMVGCLIPAWLVYKVPALHKYKGMSLYLIIVTGLLLCVSPFLAFS"
     gene            complement(4976..6340)
                     /gene="tdcG"
                     /locus_tag="IRB70_004022"
     CDS             complement(4976..6340)
                     /gene="tdcG"
                     /locus_tag="IRB70_004022"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBC0633874.1"
                     /translation="MISAFDIFKIGIGPSSSHTVGPMNAGKSFIDRLESSGLLTATSH
                     IVVDLYGSLSLTGKGHATDVAIIMGLAGNSPQDVVIDEIPAFIELVTRSGRLPVASGA
                     HIVDFPVAKNIIFHPEMLPRHENGMRITAWKGQEALLSKTYYSVGGGFIVEEEHFGLS
                     HDVETPVPYDFHSAGELLKMCDYNGLSISGLMMHNELALRSKAEIDAGFARIWQVMHD
                     GIERGMNTEGVLPGPLNVPRRAVALRRQLVSSDNISNDPMNVIDWINMYALAVSEENA
                     AGGRVVTAPTNGACGIIPAVLAYYDKFRRPVNERSIARYFLAAGAIGALYKMNASISG
                     AEVGCQGEIGVACSMAAAGLTELLGGSPAQVCNAAEIAMEHNLGLTCDPVAGQVQIPC
                     IERNAINAVKAVNAARMAMRRTSAPRVSLDKVIETMYETGKDMNDKYRETSRGGLAIK
                     VVCG"
     gene            complement(6412..6801)
                     /locus_tag="IRB70_004023"
     CDS             complement(6412..6801)
                     /locus_tag="IRB70_004023"
                     /EC_number="3.5.4.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312020.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enamine/imine deaminase"
                     /protein_id="HBC0633875.1"
                     /translation="MKKIIETQRAPGAIGPYVQGVDLGSMVFTSGQIPVCPQTGEIPA
                     DVQDQARLSLENVKAIVVAAGLSVGDIIKMTVFITDLNDFATINEVYKQFFDEHQATY
                     PTRSCVQVARLPKDVKLEIEAIAVRSA"
     gene            complement(6815..9109)
                     /gene="tdcE"
                     /locus_tag="IRB70_004024"
     CDS             complement(6815..9109)
                     /gene="tdcE"
                     /locus_tag="IRB70_004024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-ketobutyrate formate-lyase/pyruvate
                     formate-lyase"
                     /protein_id="HBC0633876.1"
                     /translation="MKVDIDTSDKLYADAWLGFKGTDWKNEINVRDFIQHNYTPYEGD
                     ESFLAEATPATTELWEKVMEGIRIENATHAPLDFDTNIATTITAHDAGYINQPLEKIV
                     GLQTDAPLKRALHPFGGINMIKSSFHAYGREMDSEFEYLFTDLRKTHNQGVFDVYSPD
                     MLRCRKSGVLTGLPDGYGRGRIIGDYRRVALYGISYLVRERELQFADLQSRLEKGEDL
                     EATIRLREELAEHRHALLQIQEMAAKYGFDISRPAQNAQEAVQWLYFAYLAAVKSQNG
                     GAMSLGRTASFLDIYIERDFKAGVLNEQQAQELIDHFIMKIRMVRFLRTPEFDSLFSG
                     DPIWATEVIGGMGLDGRTLVTKNSFRYLHTLHTMGPAPEPNLTILWSEELPIAFKKYA
                     AQVSIVTSSLQYENDDLMRTDFNSDDYAIACCVSPMVIGKQMQFFGARANLAKTLLYA
                     INGGVDEKLKIQVGPKTAPLMDDVLDYDKVMDSLDHFMDWLAVQYISALNIIHYMHDK
                     YSYEASLMALHDRDVYRTMACGIAGLSVATDSLSAIKYARVKPIRDENGLAVDFEIDG
                     EYPQYGNNDERVDSIACDLVERFMKKIKALPTYRNAVPTQSILTITSNVVYGQKTGNT
                     PDGRRAGTPFAPGANPMHGRDRKGAVASLTSVAKLPFTYAKDGISYTFSIVPAALGKE
                     DPVRKTNLVGLLDGYFHHEADVEGGQHLNVNVMNREMLLDAIEHPEKYPNLTIRVSGY
                     AVRFNALTREQQQDVISRTFTQAL"
     gene            complement(9143..10351)
                     /gene="tdcD"
                     /locus_tag="IRB70_004025"
     CDS             complement(9143..10351)
                     /gene="tdcD"
                     /locus_tag="IRB70_004025"
                     /EC_number="2.7.2.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417585.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="propionate kinase"
                     /protein_id="HBC0633877.1"
                     /translation="MNEFPVVLVINCGSSSIKFSVLDASDCEVLMSGIADGINSENAF
                     LSVNGGEPAPLAHHSYEGALKAIAFELEKRNLNDSVALIGHRIAHGGSIFTESAIITD
                     EVIDNIRRVSPLAPLHNYANLSGIESAQQLFPGVTQVAVFDTSFHQTMAPEAYLYGLP
                     WKYYEELGVRRYGFHGTSHRYVSQRAHSLLNLAEDDSGLVVAHLGNGASICAVRNGQS
                     VDTSMGMTPLEGLMMGTRSGDVDFGAMSWVASQTNQSLGDLERVVNKESGLLGISGLS
                     SDLRVLEKAWHEGHERAQLAIKTFVHRIARHIAGHAASLRRLDGIIFTGGIGENSSLI
                     RRLVMEHLAVLGVEIDTEMNNRSNSCGERIVSSENARVICAVIPTNEEKMIALDAIYL
                     GKVNAPAEFA"
     gene            complement(10377..11708)
                     /gene="tdcC"
                     /locus_tag="IRB70_004026"
     CDS             complement(10377..11708)
                     /gene="tdcC"
                     /locus_tag="IRB70_004026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine transporter TdcC"
                     /protein_id="HBC0633878.1"
                     /translation="MSTSDSIVSSQTKQSSWRKSDTTWTLGLFGTAIGAGVLFFPIRA
                     GFGGLIPILLMLVLAYPIAFYCHRALARLCLSGSNPSGNITETVEEHFGKTGGVVITF
                     LYFFAICPLLWIYGVTITNTFMTFWENQLGFAPLNRGFVALFLLLLMAFVIWFGKDLM
                     VKVMSYLVWPFIASLVLISLSLIPYWNSAVIDQVDLGSLSLTGHDGILITVWLGISIM
                     VFSFNFSPIVSSFVVSKREEYEKDFGRDFTERKCSQIISRASMLMVAVVMFFAFSCLF
                     TLSPANMAEAKAQNIPVLSYLANHFASMTGTKTTFAITLEYAASIIALVAIFKSFFGH
                     YLGTLEGLNGLILKFGYKGDKTKVSLGKLNTLSMIFIMGSTWVVAYANPNILDLIEAM
                     GAPIIASLLCLLPMYAIRKAPSLAKYRGRLDNVFVTVIGLLTILNIVYKLF"
     gene            complement(11730..12719)
                     /gene="tdcB"
                     /locus_tag="IRB70_004027"
     CDS             complement(11730..12719)
                     /gene="tdcB"
                     /locus_tag="IRB70_004027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional threonine ammonia-lyase/L-serine
                     ammonia-lyase TdcB"
                     /protein_id="HBC0633879.1"
                     /translation="MHITYDLPVAIDDIIEAKQRLAGRIYKTGMPRSNYFSERCKGEI
                     FLKFENMQRTGSFKIRGAFNKLSSLTDAEKRKGVVACSAGNHAQGVSLSCAMLGIDGK
                     VVMPKGAPKSKVAATCDYSAEVVLHGDNFNDTIAKVSEIVEMEGRIFIPPYDDPKVIA
                     GQGTIGLEIMEDLYDVDNVIVPIGGGGLIAGIAVAIKSINPTIRVIGVQSENVHGMAA
                     SFHSGEITTHRTTGTLADGCDVSRPGNLTYEIVRELVDDIVLVSEDEIRNSMIALIQR
                     NKVVTEGAGALACAALLSGKLDQYIQNRKTVSIISGGNIDLSRVSQITGFVDA"
     gene            complement(12818..13756)
                     /gene="tdcA"
                     /locus_tag="IRB70_004028"
     CDS             complement(12818..13756)
                     /gene="tdcA"
                     /locus_tag="IRB70_004028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator TdcA"
                     /protein_id="HBC0633880.1"
                     /translation="MSTILLPKTQHLVVFQEVIRSGSIGSAAKELGLTQPAVSKIIND
                     IEDYFGVELVVRKNTGVTLTPAGQLLLSRSESITREMKNMVNEISGMSSEAVVEVSFG
                     FPSLIGFTFMSGMINKFKEVFPKAQVSMYEAQLSSFLPAIRDGRLDFAIGTLSAEMKL
                     QDLHVEPLFESEFVLVASKSRTCTGTTTLESLKNEQWVLPQTNMGYYSELLTTLQRNG
                     ISIENIVKTDSVVTIYNLVLNADFLTVIPCDMTSPFGSNQFITIPVEETLPVAQYAAV
                     WSKNYRIKKAASVLVELAKEYSSYNGCRRRQLIEVG"
     gene            13945..14289
                     /gene="tdcR"
                     /locus_tag="IRB70_004029"
     CDS             13945..14289
                     /gene="tdcR"
                     /locus_tag="IRB70_004029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417589.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator TdcR"
                     /protein_id="HBC0633881.1"
                     /translation="MTGITIFYGDNIIRYVVNTKKGLRPYFKQLPDNYQAKFELNLMS
                     KFSNFIINKPFSAINNAARHIFSRYLLENKHLFYQYFKISNTDIDHLEQLINVNFLPH
                     DRTSFCECNRFP"
     gene            14545..15084
                     /locus_tag="IRB70_004030"
     CDS             14545..15084
                     /locus_tag="IRB70_004030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312027.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633882.1"
                     /translation="MKGFPIAHIFHPSIPPMHAVVNNHNRNIDYWTVKRKFAEIVSTN
                     DVNKIYSISNELRRVLSAITALNFYQGDIPSVMIRIQPENMSPFIIDISTGEHDDYII
                     QTLDVGTFAPFGEQCICSAVNKKELECIKETISKYCAKFTRKEAILTPPAHFNKTSIT
                     SDCWQILFFSPDHFNNYFY"
     gene            15106..>16008
                     /locus_tag="IRB70_004031"
     CDS             15106..>16008
                     /locus_tag="IRB70_004031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633883.1"
                     /translation="MFPVSSIGNDISSDLVRRKMNDLPESPIVNNLEALAPGIEKLKQ
                     TSIEMVTLLNALQPGGKCIITGDFQKELAYLQNVILYNDSSLRLDFFGYNARIIQRSD
                     NTCELTINEPLKNQEISTGNINVNCPLKDIYNEIRRLNVIFSCGSGGIVDLSSLDLRN
                     VDLELYDFTDKHMANTILNPFKLDDTDFTNANMFQVNFVSSKQNATISWDYLLKITPV
                     ITSINDMYSEEKIKLVESCLNALGDITEEQLKIMRLAIIESIPRAALTDQLENELTKE
                     IYKSSSKINNYLNRIKLPEMKGFSS"
BASE COUNT         4354 a         4126 c         3607 g         3921 t
ORIGIN      
        1 taacaaatat tattttccgc taaaaagttt gggaatttcc cgcagacacc aggatttcgc
       61 ctcccccata ctgtcacgac gccaggccat aataatatcg atctcgctgg tcgattccgg
      121 gctgacgaca cgcaaccgcc cttccgcaat atctttttcg accatcggat acggcatcgt
      181 cgccacgcca agccccgcca gtaatgcctg acgtttatct tcaatcgtgc tcaccgttaa
      241 gcgcggctgt ttgtccagca gttgtacggt caataccggg cgctcacgag cggtatccgc
      301 caccgcaatt ccacgatatt tcacgcgcgt cacttcagat aacggttccg gctcctgatg
      361 aatcgggtga tcaggcgcgg caacgtagac gttcattaac gtatagagct tgcgcgagtt
      421 gatctccgac gaggagcgaa aatgcatatc cggcgcgata acaatatccg cccgcccctg
      481 ctccagccgt tcccacgccc ctgccagcac ttcggtgatg attgccagtt gggtattggc
      541 ttttaccgcc agtttgtcaa ttaacgggaa aaaggcaggt gtcggtacca gcgcttcggt
      601 cacaatggtg agatgcgttt cccaaccgcg cgcgagagct tccgcatcgg tagtcagttt
      661 atctgcggct tccagcaaaa cgcgccctcg ctccagcaac atcctcccga cattggtgaa
      721 tttggtgcga tggcccgagc ggtcaaacag caccacatcc agctcttctt ccagtttttg
      781 catggtgtag ctaagtgcgg aaggcacgcg tcccagctca tccgccgccg ccgcaaaact
      841 gccccggcga tcgatcgcat ccataacccg tagtgcttcc agcgttaatg ccctttcttt
      901 ggccatttcg ttctcattca ggaaatttga acataccggg cagaatatct ggctaacaat
      961 gtagcgtcca gccccttacc ataaaaggaa gtaaagagag gtcaagaatt atgattacta
     1021 cccgaactgc caggcagtgt ggacaagcag actacggatg gttgcaggcc cggtatactt
     1081 tttcctttgg acactacttc gacccgaaat tgttaggcta tgcctccctg cgcgtgctta
     1141 accaggaagt gctggcccca ggtgccgcct ttcagccacg aacctatccc aaagtcgata
     1201 ttttaaatgt gattctggat ggagaagctg agtatcgcga cagcgaaggc aatcatgttc
     1261 aggccagcgc tggtgaggtg ttgctgctct ctacccagcc gggtgtcagc tatagcgaac
     1321 acaatctcag caaagacaaa tcgttaacgc gaatgcaact ttggctggat gcctgcccac
     1381 aacgagagaa tccgctgatt caaaaactgg cgcttaatat gagcaagcag caattaatcg
     1441 cctcgccaga aggtgggatg ggaagcctgc aattgcgcca gcaagtgtgg ctgcaccata
     1501 tcgtgctcga caaaggcgaa agtgcgaatt tccagttgca tgggccacgc gcgtatttgc
     1561 aatcgattca cgggaaattt catgcgctta cgcatcatga agagaaagcg gcgctaacct
     1621 gcggtgatgg ggcgtttatt cgtgacgagg ctaacattac gctggttgcc gattccccac
     1681 tgcgcgcttt gctgatagat ttgcctgtct agttgttttt acagggagat gatgatgagt
     1741 aaaaaatcgg ccaaaaagcg tcagccagtg aagcccgtgg tggcgaaaga accttctcgc
     1801 accgccaaaa attttggcta tgaagagatg ttgagcgagc tggaagccat cgtcgcggat
     1861 gctgaaacgc gtttagccga ggatgaagct accgcgtaaa gacaagtgcc ggatgtggcg
     1921 taaacgcctt atccggccta caaaacacaa caacatcaac aaattgtgca attcgtaggc
     1981 cggataagat gcgccagcat cgcatccggc acgataccca aaacctggcg tttatctggc
     2041 cttgctcgcc ataatctcga taatctgccg atccgtttgc tgcatcgaat ggcttgctaa
     2101 cgcacacagg ttggcaatcg actgctcaac atcatgcgcc acgattcctt cattgccggt
     2161 cactgcggta tcatccagcg ccattaacac cgctttccac gcagccgaag cactggtcga
     2221 aaccttcatc gcgcagctgt tcgacgctcc atcgcaaatc atgccgctga catcgccgat
     2281 catactgctg atcgccatcg agatggtttc ataacgccca tccaccagcc atgccatccc
     2341 ggcggcggcc cccattgctg cggtcgttgc ggcacaaagc gcagacaaac gcggtaactg
     2401 gttatggatg taaatcgcgc tcaaatgcga aagcatcagc gcacgcgcca gccgttcatc
     2461 atccgctccg aagtgttctg ctaccaccac cacaggcatt gttgcggtga tcccctggtt
     2521 acccgagccg gagttactca ttgccggaag cgtagcgccg cccatacgcg catcggatgc
     2581 cgcgctggta cgaatcacaa tggatgaaga gagatctttc gccagcaaac cgcgcgcgca
     2641 ctgtttttcc agcgtcgcac caatatgcag cccccagtta ccgctcaaac cttcctgcga
     2701 taacgcacaa tttaacttcg cagaatcgag aataaagcgg atcgccgcaa acgggacctc
     2761 attgacgaac ttcaggatct cagccagcgt cgtcctggaa agcaccgtca gcggcgactc
     2821 ttgctcgccc tctgtcacac acgcctgctg ggtaaacacc acaccattgt gcgtctcaat
     2881 atgcacaatg ttggtatgcc cgccgacaat ggtgacacac gcccacttct caccgttcca
     2941 gactttggcg cgtgagaaga ggatttcatc gcaaggttcc tggatcttaa ctgagacttt
     3001 ccccgccgcc agcagtgctt tggcatcggc aattgcctgc gcagttgcat ctttcagcac
     3061 ttccagcccg gcgttagcat ttccacctaa cgctcccagc gccgccgcaa tcggcagccc
     3121 caccattccc gtgccgggaa cggtgacgcc cagaccgttc ttcatcagat ttggcgaaac
     3181 ccaggcttct acacgttcaa ccggaccttc cagttctgcc gcagcaaccg ccgccgccag
     3241 cgccagtgaa atcggttcag tacatcccag cgccggtttt acttcctcct gaacggcgag
     3301 gatgtaacgc tgccataacg gatttaaagt cgaatcaaac atattaaaaa ccttaaaatt
     3361 tcaggtaaat caagaaaatg ccaggaacgg agaaacacaa agcaacaaac cagtgacgat
     3421 aatcaggtac agagacatcc ctttgtattt gtgcaatgcc ggtactttgt aaaccagcca
     3481 cgccgggatc aggcacccta ccatgccgaa aatcgggcta cagatagagg tgaagctcaa
     3541 caccggtgcg ttcagtacga tggcgctcca ggccagcaaa atggcgaaaa tcatgatgcc
     3601 gcgctgaacg agattttcgt taatcttctc ggcaggcatc ttgcgacgca ggatgttcat
     3661 tacgatccct tgcgttgctt cgcgaaagcc taaatagacg ccaaaaaacg cggtcattac
     3721 tgcaaagata ttgagaatga cgctgaccac tttcacccac gctgcgccat caccgctaat
     3781 aaactgtgcg gcaatcgcca gcgcggaaat attctgctcg taggctttta ccgcttcgtc
     3841 atgtcccatc gccagcgtga acgacacggc gtagaaaaag acggtgacaa acaaaatgcc
     3901 aaacgcgata ttcattgccc gcaatgcttt atgccgcgcc acttcaatcg atttttcccg
     3961 cgagcgataa gagatcacca tcgggcttaa cgtctggata aacagaatcg acgtcagggt
     4021 aaacggcagc gtaataatgg cgtttttcac cagcagcccc agcggcggta gcgaaccgac
     4081 gttatacaga tgccacattc ccaccatcga cacgcccagc gccgcgacca ccagcagctt
     4141 ggtcagcacc atccccgtcg aaattttgaa taacaatttc tcgccgcgtg aagagatcgc
     4201 caccagaatg caaatcagta ccagaccata aaagggactg tctgacagca acccttccgt
     4261 cacgccgaag gtatgcaggt aggaagcact atcgttggtg atggcggtgg aatagacgaa
     4321 catccaaatc accagcatta cgaaatagag cgcacctaac aggatgcccc agtttttacc
     4381 taaataaccg ctaatgacac tcgggtaatc tttacattct ggtgattctg ccagcgtatt
     4441 aataaacaat cgctgaaaca gatacattgc cgggtaacca atcaccgatg agagcaaaaa
     4501 tacccacaat cccatcaaac cgacctgcac cgggagaaaa acaatccccg cgccaatcgc
     4561 catcccgata ctcataatca cccagccggt gtcagtactg tcgaatttga tcgcttctcg
     4621 ccactcgctc tcactcattc cagcacgacc cgccggggtc gaagcgtctg caatgacgcc
     4681 tttattcgat gcaatttcca taatttctcg ctcaatattt tgtagggctt attatttttt
     4741 tccgagccgc atcaaggcga tatgcggtct acgtttttgc aggcgagtta ttagaataaa
     4801 gaaatgatac gcgcgaggtc agagaaaatc ttcacaatca agactttgaa ataacggaga
     4861 tggataagaa ttttctacta aattaatcac aagagaatat tcattctcta tttgcggcag
     4921 atcacaaaaa aaaggtgcac atttgtgcac ccaaggatga aagctgacag caatgtcagc
     4981 cacagaccac tttaatggcc agtcctccgc gtgatgtttc gcggtattta tcgttcatat
     5041 ctttgccggt ttcatacatc gtctcgatca ctttatcgag tgaaacacgc ggtgccgagg
     5101 tgcggcgcat cgccatccgc gcggcgttta ctgctttcac ggcattaatg gcattacgtt
     5161 caatgcacgg gatttgtacc tgtccggcaa ccggatcgca ggtcagccca aggttatgct
     5221 ccatcgcgat ttccgccgca ttgcacacct gcgccggact gccgcccagt agttcagtta
     5281 accctgccgc cgccattgaa caggccacgc caatctcccc ctgacagccg acttccgcgc
     5341 cagagatgga ggcattcatt ttatacagcg cgccaatagc ccccgcagcc agaaaatagc
     5401 gggcaattga ccgctcgttt accggacgac ggaacttatc gtaataagcc agcactgccg
     5461 gaataatgcc gcacgcaccg ttagtcggtg ccgttaccac gcgcccgcca gctgcgtttt
     5521 cttcactaac cgccagcgcg tacatgttga tccagtcgat gacattcatc ggatcgttag
     5581 agatgttatc gctggaaacc agctgacgac gcagcgctac ggcacggcgc ggcacattga
     5641 gcggaccagg cagcacgcct tcagtattca ttccacgttc aataccgtca tgcatcactt
     5701 gccagatacg ggcaaaccct gcgtcaattt ccgctttact gcgcagcgcc agctcgttgt
     5761 gcatcatcag gccagatata gacaggccgt tgtaatcaca cattttcagc agttcacctg
     5821 ctgagtggaa atcgtaaggt acgggtgttt cgacatcgtg cgacaggccg aagtgttctt
     5881 cttcgacaat aaacccgccg ccgacagagt aataggtttt gcttaatagc gcttcctgtc
     5941 ccttccaggc agtgatccgc attccgttct catggcgagg caacatttcg ggatggaaga
     6001 taatgttctt tgctacagga aaatcaacaa tatgcgcgcc agaagccacc ggcaaccgcc
     6061 cgctgcgcgt cactaactct ataaatgcag ggatctcatc aatgacaaca tcctgcggac
     6121 tgtttcctgc cagtcccatg atgatggcga catccgtggc atggcctttg cccgtcagtg
     6181 acaacgaccc gtacagatcg accacaatat ggctcgtcgc ggttaataag ccgctacttt
     6241 ccagacgatc aataaaactt tttccggcat tcattggccc cacggtatgc gaactggagg
     6301 gaccaatccc aattttgaaa atatcgaatg cactaatcat atccacaccc tcggattgcc
     6361 gttcagtgaa gtggagcgga acgaccttgc gaccgtcccg ctcacgaggc tttacgcact
     6421 acgtactgcg atggcttcaa tttccagctt cacatctttc ggcaaacgcg cgacctgcac
     6481 acagctccgg gtcgggtagg tcgcctgatg ctcatcgaag aactgcttat agacttcgtt
     6541 gatggtggca aaatcattca gatcggtgat gaacacggtc atcttgatga tatcgcccac
     6601 gctcagcccg gcagcaacca cgatcgcttt gacgttttcg aggcttaaac gcgcctgatc
     6661 ttgcacatca gccgggatct caccggtctg tgggcaaacc ggaatttgcc cagaggtgaa
     6721 gaccatgctg cctaaatcaa cgccctgaac ataagggccg attgcgcctg gcgcacgttg
     6781 cgtttcgata atctttttca tacatcctcc ggcatcaaag cgcctgggta aaggtacgtg
     6841 aaatcacatc ctgctgctgt tcacgggtca gtgcgttgaa gcgcacggcg tagccagaga
     6901 cacggattgt caggttgggg tatttttccg gatgctcaat ggcatccagc aacatttccc
     6961 gattcatcac gttgacgttg aggtgctgac cgccttccac atccgcttcg tggtggaaat
     7021 aaccatccag caggccgaca aggttggttt tgcgtaccgg atcttctttg cccagcgccg
     7081 ccgggacaat tgagaaggtg tacgagatcc cgtctttggc gtaggtgaac ggcagtttcg
     7141 ccaccgacgt cagcgaggct accgcacctt tgcggtcacg accgtgcatc gggttagcgc
     7201 ccggtgcgaa cggtgttccg gcgcgacgac cgtctggcgt gttaccggtt ttctggccgt
     7261 acaccacgtt agaagtgata gtcagaatcg actgggtggg gacggcgttg cgataggttg
     7321 gcagcgcttt aattttcttc ataaagcgtt caaccagatc gcaggcaatg ctgtctacgc
     7381 gctcgtcgtt gttgccatac tgcggatatt cgccgtcgat ttcgaaatcc accgccaggc
     7441 cgttttcgtc acggatcggt ttcacgcggg catatttgat ggcagacagg gagtccgtcg
     7501 ccaccgacag acccgcgatg ccgcaagcca tcgtgcgata aacatcacga tcgtgcagcg
     7561 ccatcagcga agcttcgtag ctgtacttgt cgtgcatgta gtgaatgata ttcagcgcgc
     7621 tgatgtactg caccgccagc cagtccatga agtgatcgag actgtccatc actttgtcgt
     7681 aatccagcac gtcgtccatc agcggtgccg ttttcggacc gacctgaatc ttcagcttct
     7741 catccacccc gccgttaatt gcgtacagca gcgttttcgc caggttagcg cgtgcaccaa
     7801 agaactgcat ttgcttacca atcaccattg ggctgacgca gcaggcaatc gcgtaatcgt
     7861 cgctgttgaa gtcagtacgc atcagatcgt cgttttcata ctgcaaggaa gaggtgacga
     7921 tagacacctg cgcagcatat tttttgaagg cgatcggtaa ttcttccgac cacagaatgg
     7981 tcaggtttgg ttccggtgct ggccccatag tgtgcagggt gtgcagataa cggaaagagt
     8041 ttttggtcac cagcgtacga ccgtccagcc ccatcccacc gatcacttcc gtcgcccaga
     8101 ttgggtcgcc ggagaacagc gaatcaaatt ccggcgtacg caggaagcgc accatacgga
     8161 tcttcataat gaagtggtcg atcagttcct gtgcctgctg ctcattgagg acgccagctt
     8221 taaagtcgcg ctcaatgtag atatcgagga acgatgccgt gcggcccagc gacatcgcgc
     8281 cgccattttg cgatttcact gccgccagat aagcgaagta gagccactgc accgcttcct
     8341 gcgcattctg cgccgggcga gagatatcaa agccatattt cgccgccatt tcctgaatct
     8401 gcaacagcgc atgacgatgc tctgccagct cctcacgcag acggatggtg gcttccagat
     8461 cctcgccttt ttccagacgg gactggagat cggcaaattg cagttcgcgt tcacgcacca
     8521 gataactgat gccatatagc gccacgcggc gatagtcacc gataatgcgc ccacgaccat
     8581 agccatctgg taaaccggtc agcacgccag atttacggca gcgcagcata tccggtgagt
     8641 aaacatcaaa tacgccctgg ttatgggttt tacgcagatc ggtaaacaga tattcaaatt
     8701 cactgtccat ttcacgacca taggcgtgga atgaactttt aatcatatta atgccaccga
     8761 acggatgcag cgcacgcttt aatggcgcat ccgtttgcag gcccactatt ttttccagcg
     8821 gctggttaat atatcccgca tcatgagcgg taatggtggt agcaatatta gtatcgaaat
     8881 ccaatggcgc gtgagtcgca ttttcgatac ggatgccttc catcactttt tcccacaatt
     8941 ccgtggtggc aggcgtcgct tcggcgagaa aagattcatc gccttcataa ggtgtatagt
     9001 tatgttgaat aaaatcgcgg acattaattt cgtttttcca gtccgtacct ttaaagccaa
     9061 gccatgcgtc ggcgtacagc ttatcgctgg tatcaatatc taccttcatg aaaaataatc
     9121 tctctacaat acttcaacta aattatgcaa attctgcggg cgcgttaact ttgcctaaat
     9181 aaatggcatc caaagcaatc attttttctt cgttggttgg gataacggcg caaatgacac
     9241 gcgcattttc actggaaaca attcgctcac cacaggagtt agagcgatta ttcatttctg
     9301 tatcaatctc tacgcctaat acagccaaat gttccatgac cagacgacga attaaacttg
     9361 aattctctcc tattccgccg gtgaatataa ttccatccag gcgacgtaat gaggctgcgt
     9421 gtccggcaat atggcgggca attcggtgaa caaaggtttt aattgccagt tgcgcgcgtt
     9481 cgtgaccttc atgccaggct ttttccagaa cacgtaaatc cgaagaaaga ccggaaatac
     9541 ctaataatcc cgactcttta ttcactacgc gttccaggtc acccaggctc tggttggttt
     9601 ggctggcgac ccaggacatc gcaccaaagt cgacatcgcc actgcgggta cccatcatca
     9661 agccttccag cggcgtcatt cccattgagg tatcaacact ctgaccgttg cgaactgcgc
     9721 agattgacgc gccattgcca agatgcgcca caaccaggcc ggagtcatct tccgccagat
     9781 tcagcaaaga atgtgcgcgc tgggaaacat agcggtgcga cgtgccgtgg aaaccataac
     9841 ggcgtacacc taactcttca taatatttcc acggcaggcc gtataaataa gcttccggag
     9901 ccatcgtctg gtggaaactg gtatcaaata ccgccacctg agttacgccc ggaaataatt
     9961 gctgcgccga ttcaataccg cttaaattgg cgtaattatg caggggtgcc agtggagaaa
    10021 cgcgacggat attatcaatg acttcatcgg taataatggc ggactcggta aaaatactgc
    10081 cgccgtgagc gatgcggtgg ccaattaagg ccacactgtc atttaaattc cgtttttcca
    10141 gttcaaatgc aattgccttc aatgcacctt cgtagctgtg gtgagccagc ggtgctggct
    10201 ctcccccatt tacggataag aatgcatttt ccgagttaat accgtcggca atacctgaca
    10261 ttaatacttc acagtcgctg gcatcgagta cggaaaactt aatcgaagac gaaccacagt
    10321 taataaccaa aacaaccgga aattcattca tctcttttct catcctgagt tacggattaa
    10381 aacagtttgt atacgatgtt caggatggtc agcagaccaa tcacggtaac aaacacgtta
    10441 tccagacgac cacggtattt cgccagagac ggcgctttac ggatggcata catcggcaac
    10501 aggcacagca gggatgcgat aatcggtgcg cccatggctt caatcaggtc gaggatgttc
    10561 gggttggcgt aggcaacaac ccaggtggag cccatgatga agatcatgct gagagtattc
    10621 agtttaccca gcgacacttt ggttttgtca cctttataac cgaacttcag aatcaggcca
    10681 ttcaagcctt ccagcgtccc cagatagtga ccgaagaaag atttgaagat agccacgagt
    10741 gcgatgatgg aagccgcata ttccagtgta atcgcgaacg ttgttttggt accggtcatg
    10801 gacgcaaagt ggttagccag ataagaaagc actggaatat tctgcgcttt ggcttccgcc
    10861 atgttggccg gagacagcgt aaacaggcag ctaaaggcaa agaacatcac cactgcaacc
    10921 atcagcatgc tggcacgaga aatgatttgg gaacatttac gttcggtgaa gtcgcgaccg
    10981 aagtctttct catactcttc acgtttagaa accacgaagg aagagacgat tggcgagaag
    11041 ttaaaggaga aaaccatgat ggaaatcccc agccagacag tgatcaggat accgtcatga
    11101 ccagttaacg acagcgaacc gaggtcaacc tggtcgataa ctgcagagtt ccagtaaggg
    11161 atcagcgaca gagaaatcag caccaggctg gcgataaacg gccataccag gtagctcatc
    11221 actttaacca tcagatcctt accaaaccag atgacgaaag ccatcagcag caacaggaac
    11281 agcgccacaa agccgcgatt cagcggtgca aagccgagct ggttttccca gaacgtcata
    11341 aaggtattgg taatagtaac gccataaatc cacagcagtg ggcaaatcgc gaagaagtac
    11401 aggaacgtga taaccacgcc gccagtttta ccaaaatgct cttccaccgt ttccgtaatg
    11461 ttgccggaag ggttagagcc agaaagacac agacgcgcca gcgcccggtg gcaataaaac
    11521 gcgatggggt atgccaatac caacatcaga agaatcggga tcagcccgcc aaaacctgcg
    11581 cggataggga agaacagcac cccggcgccg attgccgtac caaacaagcc taacgtccat
    11641 gtggtatctg atttacgcca ggacgattgt tttgtctggc tggatacaat gctatctgaa
    11701 gtactcatat cctatcctca acgaattaat taagcgtcaa cgaaaccggt gatttgagag
    11761 acgcgagaaa gatcgatatt gccgccggaa ataatactga cggtttttct gttttgaata
    11821 tattggtcta atttaccgct taataatgca gcacatgcca gagcgcctgc gccttcggtg
    11881 acgactttat tgcgctgaat taaggcaatc atactgtttc tgatttcgtc ttcgctgacc
    11941 agcacgatgt catcgactaa ttcacgaacg atttcgtaag ttaaattacc cgggcgggag
    12001 acatcacaac catccgccag ggtgccggta gttcggtgcg tggttatttc tccggagtgg
    12061 aaagaagccg ccatgccgtg aacgttttca gactgtacgc caataacacg aatggtcggg
    12121 ttaatagatt taattgccac cgcaatacca gcaattaaac cgccaccacc aattggcaca
    12181 atcacgttat cgacatcata gagatcttcc ataatttcca gaccaatcgt tccctggcca
    12241 gcaatcactt tcggatcatc gtaaggtggg ataaaaatac ggccttccat ttcgacaatt
    12301 tcgctcactt tagcgatagt gtcgttgaag ttatcaccat gcagaacgac ttctgcggag
    12361 tagtcgcacg ttgccgctac tttggatttt ggcgcacctt ttggcatcac cactttaccg
    12421 tcgatgccca gcatcgcgca ggagagggaa accccttgcg catggttgcc cgcagaacag
    12481 gccaccacgc ctttgcgttt ttccgcatcg gtcagtgaac ttaatttatt aaatgcgcca
    12541 cgaattttaa atgaaccggt acgctgcata ttttcaaact tcaggaatat ttcacctttg
    12601 caacgttcac taaaatagtt ggagcgaggc atgcctgttt tataaattcg cccagccagt
    12661 cgttgtttcg cttcaataat gtcatcaata gcaaccggca gatcgtatgt aatatgcatt
    12721 ataaaacctc ttcgcctgaa ttaaatatgt aggtaaccgt aaccgacacc tgcaagacag
    12781 acaggtggat tatttatgtt taaataaaaa taaataacta accaacttct attaattgcc
    12841 ttcgtctaca cccattataa gatgaatact ctttggctaa ttccaccaaa accgatgctg
    12901 cttttttaat acgataattt ttcgaccata ccgcggcata ttgtgccaca ggtaatgttt
    12961 cttcaaccgg aatagtaata aattgattag aaccaaaagg tgatgtcata tcacatggaa
    13021 ttacagttaa gaaatcagca ttgagaacaa gattataaat tgtcacgact gagtcggttt
    13081 taacgatgtt ttcaatactg atgccatttc tttgtaacgt agtaagcagc tcgctgtagt
    13141 accccatatt ggtttgtggc aacacccact gttcgttctt caacgactcc agcgtggtgg
    13201 tgccggtgca tgttcgggac ttactggcta ccagcacaaa ctcggactcg aacagcggct
    13261 caacatgtaa atcctgaagc ttcatttctg cgcttaacgt accaatcgca aaatcaagtc
    13321 gaccgtcgcg gattgccggt aagaacgaag acagttgcgc ttcatacata gaaacctgcg
    13381 ctttcgggaa cacctctttg aacttgttga tcatccctga cataaaagta aaaccaatca
    13441 atgaaggaaa accaaatgag acttccacca ccgcctcaga agacataccg cttatctcat
    13501 taaccatatt tttcatttca cgggtaatgg attcggaacg agagagtaac aattgaccgg
    13561 caggtgttaa tgttacaccg gtatttttcc gcaccactaa ttccacacca aaataatctt
    13621 caatatcgtt aatgatttta ctgacggccg gttgagttaa ccctaattct tttgcagccg
    13681 agccgataga accacttcta atgacttcct gaaagactac caggtgctgc gttttcggaa
    13741 gaagaatagt gctcataacg acctacgtta attacctcat tgacggcatg aagtgtatca
    13801 aaatgaaatg aacaggatat gtgcgaccac tcacaaatta actttcaata ctttccaggg
    13861 taacttcacg tcaattaaat acctttaaat atcaataagt taaagtataa aaatcagcat
    13921 aaaccctgat ttttgtcaaa aaaaatgacg gggataacca tattttatgg cgataacatc
    13981 attcgttatg tggttaatac aaaaaagggg ctgagaccat atttcaagca attaccggat
    14041 aattaccagg caaaatttga gttaaattta atgagcaagt tctcaaattt tattataaat
    14101 aaaccatttt cagcgataaa taatgcggca cgtcacattt tttcacgcta tttgttggag
    14161 aacaaacatt tattttatca atattttaaa atttcgaata cagatattga tcatctcgaa
    14221 caattgatta acgtcaactt tctccctcat gacaggacgt cattttgtga atgcaatcgt
    14281 tttccataaa ttcttctccc ctcataggtg acgaatagca ttttgtgttg aggatcacaa
    14341 aacgaataat tgctggtcgc cgcgataagg tcagccaaag acaacaaggg gaattttcac
    14401 agagcttttg atcggcgtag gccacagaat gttgcttcgt ttactgtaat gccgggtaaa
    14461 tgagcgtttt ttgatagtgc gaaagtgccg tgcgaggaaa ataagcatct attattgttt
    14521 gtcatgatga caaggcaggc atcaatgaaa ggcttcccaa ttgcacatat ttttcaccct
    14581 tcaatcccgc caatgcacgc agtggttaac aatcacaaca gaaatattga ttattggacg
    14641 gtaaaaagaa agtttgcaga aattgtctcc accaatgacg ttaataaaat atacagtata
    14701 agtaatgaac tgcggagagt attatctgca attactgcat tgaatttcta tcaaggcgat
    14761 attccttctg tcatgatccg aatccaaccg gaaaatatga gtccattcat catagatatt
    14821 tctacaggag aacatgacga ttatatcata caaacattag atgtaggcac ttttgcacct
    14881 tttggtgaac aatgtatttg ctcagccgtc aataaaaaag agctggaatg tattaaggag
    14941 acgatttcta agtattgtgc aaaattcacc cgaaaagaag ccatcttaac acctcctgcg
    15001 cactttaata aaaccagcat tacttcagat tgttggcaaa ttctcttttt ttcacccgat
    15061 cattttaata attattttta ttgattattt ataaaggata aaataatgtt ccctgtttca
    15121 tcaattggta atgatattag tagtgattta gtccgtcgaa aaatgaatga tcttcctgaa
    15181 agccccatag ttaataacct cgaagcacta gcaccaggta tagaaaaact aaaacagacc
    15241 tctattgaaa tggtcacttt acttaacgcg ttacaaccag gtgggaaatg cattatcact
    15301 ggtgattttc aaaaagaatt agcgtactta caaaatgtaa ttctttataa tgattcgtct
    15361 cttcgtctgg atttttttgg ttataacgcc cgaattattc aacgatcaga caatacctgt
    15421 gaacttacaa ttaatgaacc gttaaaaaac caggaaatat ccacaggcaa tatcaatgtt
    15481 aattgcccat tgaaagacat ttacaatgaa atcaggaggt tgaacgtaat ctttagttgt
    15541 gggagtggag gtatagttga tctatcctct ctggacttac ggaatgtcga tttagaactt
    15601 tatgatttta cagataaaca tatggccaat acaattttaa atccttttaa attggatgac
    15661 acagatttta ctaatgccaa catgtttcag gtaaatttcg ttagttcaaa acaaaacgcc
    15721 acaatctcat gggattattt actaaaaata acgcctgtta taacaagcat taacgatatg
    15781 tattctgaag aaaaaattaa gcttgtcgaa agttgtttaa atgcgcttgg agatattacc
    15841 gaagaacaat taaaaatcat gagacttgca attatagaat ctataccaag agcagctcta
    15901 acagatcaat tagaaaatga attaacaaaa gaaatatata aaagctcatc gaaaattaac
    15961 aattacttga acagaattaa attaccagag atgaaaggat tctcatca
//
LOCUS       DADXDL010000105        15620 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.105, whole genome shotgun sequence.
ACCESSION   DADXDL010000105 DADXDL010000000
VERSION     DADXDL010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 15620)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15620)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15620
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.105"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(205..402)
                     /locus_tag="IRB70_004032"
     CDS             complement(205..402)
                     /locus_tag="IRB70_004032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HBC0633884.1"
                     /translation="MNTNRILRKKEVLHLTGISSATLYRLISKGAFPLSKKLTGDSGR
                     AVGWLESDINNWVNSRMQAGE"
     gene            626..1240
                     /locus_tag="IRB70_004033"
     CDS             626..1240
                     /locus_tag="IRB70_004033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000580009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633885.1"
                     /translation="MIGNQSNKADARCHRERKSSNEVFEFLEKKLYLGRDTRQKLALI
                     ARKLTGAGFSPDKFAAEKAADVLSACVNHMFNDLLNEGELNGIYRSEEHPMIVPARSP
                     KALEIYTVYQLVKGRFDKLHTGESDREKYASVAEKLNEYGIWKPRLKRLSDGKEWARE
                     DVAWVLQPENINALINVQNQKYARLSAEDKTKAASGNGSKAKNT"
     gene            complement(1227..2156)
                     /locus_tag="IRB70_004034"
     CDS             complement(1227..2156)
                     /locus_tag="IRB70_004034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019083242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBC0633886.1"
                     /translation="MSRAVLRQVVPVVQTTVFDAYTGGLAPSGRRGITSLLNRSASIL
                     KRGTDAVDYPWEQLNYAAVAKVRAALLDDGYAVSSVNMALSALRGVAQTAFNLNYMDA
                     ETLARIRSVKRVSGDIQRKGRALDRQEIRALIQAARQHPQPVRRCRDTAIVLTLCGTG
                     LRAGELVKLERRDYANGILTVRQGKGRKYREIHVADAVDKAIRVWLKVSADEADSALF
                     RRIQRSGKVASQPLTTTGLTGILADLQQTSGIARFTPHDMRRTFITRLLEQGVDINTV
                     RQLAGHSDISTTTRYDCRGESMKVSASKRIRCF"
     gene            complement(2203..2655)
                     /gene="radC"
                     /locus_tag="IRB70_004035"
     CDS             complement(2203..2655)
                     /gene="radC"
                     /locus_tag="IRB70_004035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000177771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBC0633887.1"
                     /translation="MTMFTQRETRILDQARDIISRYYQRGVQLCSPDDVRRCVMVELA
                     PLEHEEFGIILLDNQNQLLHREILFRGTLNSVSVHPREVIKRVLKNNAAAVILVHNHP
                     SGEPEPSRCDIQLTKKLQELLEMLDVRLLDHFIVAGTETVSMAERGLV"
     gene            complement(2657..3118)
                     /locus_tag="IRB70_004036"
     CDS             complement(2657..3118)
                     /locus_tag="IRB70_004036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000954131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633888.1"
                     /translation="MLSWLYDGRVKRRPLMNRLIQTYQQRWPLHEWLTEGIEEDRLDW
                     LIAQVLQKGHYRRQFPVEITRPFAGKRGLTDGRLFREMQRFLDVTDHSRLIMLSDQFH
                     WSLLVKMDEEMLCFFDSNGRTTMSRKAFSLRTGVTRRQLFPDAIYFIEREF"
     gene            complement(3238..3630)
                     /locus_tag="IRB70_004037"
     CDS             complement(3238..3630)
                     /locus_tag="IRB70_004037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001357433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2787 family protein"
                     /protein_id="HBC0633889.1"
                     /translation="MPVDQELINIIINEAGNPPPHKAKITAVSLLFKDQCYSTEKGGY
                     HPVEIRLISRNDEWYFDYITDFSYMGVVYPELEKEIDISWSQQYVFLAYVGDLPVNAG
                     RELFELWQSNFIQYHAMNVYTITVLWGS"
     gene            complement(3892..4266)
                     /locus_tag="IRB70_004038"
     CDS             complement(3892..4266)
                     /locus_tag="IRB70_004038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000068011.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0633890.1"
                     /translation="MVKLMADSADKLVGQRIQTRRKEAGLTAADLAETIDISQQQLSR
                     YERGTNKINIAHLVKIAVALKTPISWFFIDCMEDLNVSDIPINYATGLDVELKQRLEQ
                     VWNKLDNPKRKSLIMFLDEFIK"
     gene            4456..4983
                     /locus_tag="IRB70_004039"
     CDS             4456..4983
                     /locus_tag="IRB70_004039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001576751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633891.1"
                     /translation="MATTITEIMECFEYFFSSLYRREFVKTLRLNECSERELLPLVRC
                     YLLGWFADNVSPEVKSKLPGTVSGHGYIDFVIDDVAVEFAVRKPTAARSNVSATVNST
                     EVKKLMKHDGKALLVLFDFSDAPYSEEQIESFRNWPSLGRGNHRKSAFNVVYFFVEKR
                     RPLALGKITKNIRIT"
     gene            4998..5357
                     /locus_tag="IRB70_004040"
     CDS             4998..5357
                     /locus_tag="IRB70_004040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA dehydrogenase"
                     /protein_id="HBC0633892.1"
                     /translation="MNRKLLALLMAAITLPVAAAQYVKPGAVLTLNPGKGNAEFNINA
                     STGDGSGVCNMDGTAQQIAAGESQKRRWVWNDNASQCVAVISELKNGKASVMTRGCEG
                     YCGAPATGAMDGLFNKK"
     gene            5388..5723
                     /locus_tag="IRB70_004041"
     CDS             5388..5723
                     /locus_tag="IRB70_004041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016247044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633893.1"
                     /translation="MKRTMLLVLIAAGLLAGCGEKTPKCSSDDAKNLVVDIARKTIEK
                     GMTLDKDVRISVENVRTISYESGLDVYQCAADLTFTKPDLQNSLPITYRIQKTDEGKG
                     QSYINVSGL"
     gene            complement(5911..11094)
                     /locus_tag="IRB70_004042"
     CDS             complement(5911..11094)
                     /locus_tag="IRB70_004042"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633894.1"
                     /translation="MREQHTLPEDKSPGTSTLASGPAGTHFEAQVAASYMLAMLAGAP
                     ARGLPGASIDRVALQQANAGYPLDDVIIHGHDNISGKVAVLEVQVKRSITFAASDPVF
                     RKVVGQIVKASQRPDFSTQRYELAIATTKGSRKIDGAYQDVLTLARQISDATTFAAQI
                     DLAGVANDDMRSFVKTFKTHLLDEGSPDDNETVWFLLRRIQILTFDFTAPGSASHDLA
                     LERALRILHADDGSRVGAFWGSLIELSIDVAKSGGDKTRDTALVTLAQFGYRFLGERR
                     HMAARAALTESSRLALADIRNRVGKAVLARQERVAAIHAALGLGRYVEIRGDAGVGKS
                     GILRQMAEAMQTEGPVIVLSPGRCVPRGWVAWRAQLGFDGTLRELLVELANDGGATIY
                     IDNLDFFNAEERLTVVDIVSEASIVPGLVIVATARLESGLDEPNWLPNDALARLGLTE
                     PIIIDELSKAEVEQLKAIDPSLAPLLTEGHPARQVARNLFRLSRLASQTASEPMPRTE
                     VDMAEQWWINADGTRDAGWRDRSRLLQDLAFQILSGADFLDIKCHSAIPIDALVSSGT
                     LRNLSTDLVAFRHDVLREWAIANAIHSDPRLIDGLQLDRPATAMFARGIELAARMAVE
                     RAVDGVKWLAIVERLSQVGVHQSWRRAALLALARSEAAETLLSRASPELLANRAALLR
                     ELIRIVMAVDVLPAAKVFAAAGVDPALIPPSVNIPRGPAWIALITWLLDTAEIAPIEA
                     IPDIVQLYTAFSIGTLGITDITALTTRQIYGWLRLLEPRNEMLLPGEEPLFRGHLDRN
                     GTQSLKSDLRDAFIIFARTTPELAAEYLTAVGSCEHNEYIVRSILKMRGTLAQAAPVE
                     LANLTAQALISGPRGRKRHFGTEREEAFTYLDHVFLPVSPDQGPFLDLLINSPKNGLA
                     LIHRLVTHAVAHESQGADSGINGFKLVLPKGVRTFPWSQTYFWSRNSNFYAVTSSLMA
                     LEAWAHRRVDAGEAFEDVLTDVLGPPGSCAAYLLVGVDLIISHWPKSLRIATAFLGCP
                     ELLCLDRIRQVHDRVEIPEFFDLNTARSESQGNMIAADLQRRSSRRTTLDELIGSFTF
                     QASLEQRTALRMLLVSEAARLGEPVASSNLRSPEFMVRYALNLSDATNWQEFEMTLKD
                     GSSTTARKYVSPPAEQTHLQALRDAATERESDFATCSVLTLAIDDPSQLLPEGRIVAV
                     AWARRLAMATTDIESDDDDDERWMQEEAFVAAAMIVMRDGNDALYAEHGEWARSQLGK
                     TLVALDDNPVRQMRGGLRFNPTAIAYAGLIHALRHRSTTEDVRSLLEVAARGNHAAAH
                     GLGTSVSVLAAVDSRLPRSILRCAFSACVVEERVWDASEEEVEARKARSHERARAAVA
                     AEISWLNSDGTEPLWPVFPEERARPGRRLRLREVSMAASKQPEVSIAPPKVHADHQAA
                     ALWLRQVNIVSEDAALSWLSEVVKSYMPWTIVANGANLDDGDETDQPPSEWNNTFFDL
                     AARCVVGLSSSEVIELVVQHIITLPDQNFYDVLVDFLRNFDVVYFGGNSIPTQIAIDV
                     RKVLVDHMLTTRGWGRLNRSRDLSIEMHLGPAIAVLFFNDQMFGKGSKCYLLEKGMDR
                     IGPFLPILDKLVSKGPSPFVALLLLNLLEVAPRAEQLNMLVGAVCVWLEVYPDFQQLW
                     IDYGVGRRWCLVMEAILGRSPCSFSNSAPLRPAIDNFVASLVALGVPEAARLEEELGK
                     L"
     gene            11487..15518
                     /locus_tag="IRB70_004043"
     CDS             11487..15518
                     /locus_tag="IRB70_004043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0633895.1"
                     /translation="MNELLLPEQVKAARALLAWSQQELASKANVATSTLADFERGFRT
                     PVANNAQAIRDALEAEGLQFIAGGVVERGMLQPPENVKPGSLMRWINATHLSQWGERR
                     DGQSGIPELLRRLIFATVGPAAKVHFPSDESVQYPGWDGECKTSLGLGFVPEGDSVWE
                     IGAQRTSIRAKAEEDFNKRSGNPLGYSPDKTTYVFVTPQRFPGKNKWVEEKKALNIWL
                     NVCAIDADDLVHWLEIYPAVAQWLSVKIGHRPQGLRNIEESWSEWIHATRTPLTPDVI
                     LAGRDEEQTKVLRWLRDSPQQLSVQAEAPDEALAFLYASISPLPEEHKLFYWSKCVVV
                     DNATTARQLAGLGTPLIIVLTISEPGIAQSLVNNGHHVYAIYGSDVSHLSGHSIRLPR
                     PWRFELKIALTHAGLNEEDAHRYAHASGRSITVLRRLMPIAPNYKPQWAEHVSSELIA
                     AMFAGSWDETSSQDQKIISDLAGCSYEQVEEILAPLASTFGGPLIRSGNLWKVVSLRD
                     LWTQVGNQLTSHQLKRFENTFHSVVSAIDPHFETQPNADTFYEDNSVGKPSGSIRRGL
                     TESMIALAVFPEVATLITDVSSHVNSAVYKLLNNATEPLWWSLSQDFHNLAEAAPTVF
                     LDAVEAGLEGDSPQILSLFRSDEGIMHPTEYLSNLLWALEMLARSPRYLMQSALLLAW
                     LDDVDPGGRWGNRPAVSLRRIFVSWSPQTYANSSQRIKVIDRIISLHPIAGWKLLLAL
                     APRSHDTSEPSSMPNWRDFTPNEPESITWSSVATAACEIGERLLMHINGRCERWFELF
                     HLWGNFDSNWKFSAAKQLADYSLNLTSSDEKERLWNELRHFLQRNRGFKDAPWALSEE
                     ELAPLDAIFLSLTPENVEERFRWLFCAGANELGENYDWQTQRNRLEERQLEAVEFLLA
                     ELEFEQIFHFSSTITLHSDFGLALARSSTKCGHKHFLMKKALMSGDSDIANIGLGILY
                     GLKATKGSESETWVQEIWEQAITDNWGELAEVRISQVLPPVMSLWLKIESRPVNISTI
                     YWQTIPTFRLSADLELEYVIDHLLLADRSHDALAWLANNIKIEPEGSVIIRVMHTAAS
                     TKDSPNNDNTMSSYYIGILLDYLESDVNTSKEELVRLEWIYFQVLRHSRHPARNLHQA
                     LAKDPVFFTSLMKLLYLPEEDSGVVESEPANPKQARDLASQAYQVLHDWAIVPGTDEN
                     GTIDSYALMSWVKQARQLLKSAGRGEIGDDKIGMILSAAKRKKNETWPPEAIREVLEF
                     ARSRAMESGFEVGVYNRRGVTVRMPHDGGGQERILVERYKQDADDLRFEWPRTAACLD
                     RIAISYQQDAIREDHSADQGDWL"
BASE COUNT         4134 a         3767 c         3727 g         3992 t
ORIGIN      
        1 tcctcccacc agtgctcccc tcttttgatg gcatcagaca aaatccgtgc agatacccgg
       61 ttaagcttac gtatccgcaa ctgttgttcc cttaatatgg cagcggtagt acgtttcgat
      121 aacccaacct gtttccccat ggtttcaaac caggggactg ctatttcttt cgcagaactt
      181 gttttagcta ttatctcttt cattttattc tcccgcctgc atacgactgt taacccagtt
      241 attgatatca ctctccagcc aacccaccgc ccggccactg tcgcccgtta gcttctttga
      301 caaaggaaag gctcctttcg agatgagtcg gtacaacgtc gctgacgaga tccccgtcag
      361 atgaagaacc tcttttttac gcaaaatacg gttggtgttc atgcttgtgc tcctttgagc
      421 tgtttcagga gcggggttat ttacaaccac caaaaaacgc aaggattcac tcaacgatgc
      481 cttcgttgag cactttaagg gcatctttaa tgtggatgtc attcgagatc atctatttct
      541 gtctccacaa cggtcatata aagaagcaat tttcactgag gctcaatggt gatattttgt
      601 acaaaatgct ctcatggagg tgactatgat tggtaaccaa agcaacaagg ctgacgccag
      661 atgccaccgg gaacggaaaa gcagtaacga ggtctttgaa tttctggaga agaagctcta
      721 tctggggcgg gatacccggc aaaagctggc actgattgcc cggaaactga cgggagcggg
      781 ttttagcccg gataaattcg ctgcagagaa agcggcggat gtgctgagtg cctgcgtgaa
      841 ccacatgttt aatgacctgc tcaatgaggg agagctaaac gggatttata ggtcggagga
      901 acaccccatg atagtcccgg ccaggtcccc taaggcactg gaaatctaca ctgtttacca
      961 gcttgtaaaa ggtcgttttg acaagcttca tacgggggag tcagatcgtg agaaatatgc
     1021 ttcggtagca gaaaaactta atgagtatgg aatatggaaa ccccggttaa aacgactctc
     1081 tgacggtaaa gaatgggcgc gtgaggatgt tgcgtgggta cttcagcctg aaaatatcaa
     1141 tgcactgatt aacgtccaga atcaaaagta cgcgcggttg agtgctgaag ataaaactaa
     1201 agccgcgtct ggaaacggct caaaagctaa aaacacctga tgcgtttgct ggcgctgact
     1261 ttcatgctct caccacgaca gtcatagcgc gtcgtcgtgg atatgtcgct gtggcctgcc
     1321 agttggcgga cggtgttgat atccacgccc tgctccagta aacgggtgat gaaggtgcgc
     1381 cgcatgtcat gtggggtgaa acgtgcaata cctgacgtct gctgtaaatc agccaggata
     1441 cccgttaacc cggtcgtagt cagcggttgg cttgcgacct taccactacg ctgaattcgc
     1501 ctgaacaacg cactgtcagc ctcgtctgca ctgaccttca gccatacgcg gatagcttta
     1561 tccactgcat ccgccacgtg aatttcacgg tatttgcgcc ccttcccttg cctgactgtc
     1621 aggatgccat tggcatagtc ccggcgctca agtttgacca gttccccggc ccgcaggccc
     1681 gttccacaaa gagtcagcac tatggcggta tcacgacagc gccgtaccgg ttgcggatgt
     1741 tgtcttgcgg cctgaatcag cgcccggatt tcctgcctgt ctaatgccct tcctttacgc
     1801 tggatatcgc cgctcacgcg cttaactgac cggatacgtg ccagcgtttc ggcatccata
     1861 taattgaggt taaaggctgt ctgtgccacg ccccggagtg ctgacagcgc catgttcacc
     1921 gacgacacgg cgtaaccgtc atccagcagt gccgcacgta ctttagcgac ggcggcgtag
     1981 ttaagttgtt cccacgggta gtctactgca tcagtaccgc gtttaagtat gctggcgctg
     2041 cggtttaaca ggctggtgat gcctcgccgc cctgagggtg ccagaccgcc agtatacgca
     2101 tcaaacacgg ttgtttgcac caccggcacg acctgacgta acactgccct gctcatgcgc
     2161 gtaacccgca ataacgtaca ttaaaccagg taactttcag catcacacca gcccccgttc
     2221 agccatcgac accgtttcag tccccgccac gataaagtgg tcaagcaacc ggacatccag
     2281 catttccagc agctcctgaa gctttttggt caactggatg tcacaccggc tgggttcagg
     2341 ctcgccgctg gggtggttgt ggacaaggat gactgcggcg gcgttatttt tcagtacacg
     2401 cttaataact tcacgggggt gaacgctgac cgagtttaac gtacccctga acaggatttc
     2461 gcggtgcagc agctgattct gattatcgag caggatgatg ccaaactctt catgttcaag
     2521 cggtgccagc tcaaccatta cgcaccgccg aacatcatca ggggaacaga gctgaacgcc
     2581 acgctggtag taccggctga taatgtcacg cgcctggtca aggatacggg tttcacgctg
     2641 ggtaaacatg gtcatgtcag aactcccgtt caatgaagta aatggcgtct gggaacagct
     2701 ggcggcgggt tacgccagta cgaagggaga aagctttacg ggacatggtg gttcgcccgt
     2761 tgctgtcgaa gaagcagagc atttcttcgt ccattttgac cagaagggac cagtgaaact
     2821 ggtcgctgag cataatcagg cgagagtggt cagtgacgtc aagaaaccgc tgcatttccc
     2881 tgaacagccg cccgtctgtt aacccccgct tccctgcaaa gggtctggtg atttcaaccg
     2941 ggaactggcg gcggtaatgc cctttctgca acacctgagc tattaaccag tctaagcggt
     3001 cttcttcaat tccttcagtc agccattcat gcaaaggcca gcgctgctga taagtctgaa
     3061 taagccggtt cattaacggg cgtcgtttca ccctgccgtc atacagccag ctcagcatgt
     3121 taaccacgca ataagcaccg caaagacagt ccagttcgcc ctgttgagac gcacgtatcc
     3181 ctctgtcagt cgtcacagat aattccccat aaagtagtga tagttagtgc agaaggatta
     3241 gcttccccac aggacggtaa tggtgtagac gttcatggcg tgatactgaa taaagttgga
     3301 ttgccagagt tcaaacagct cccttccagc gttaacaggc aggtcaccaa cataagcaag
     3361 aaagacatat tgctgactcc agctgatatc aatttccttt tccagttcgg ggtacaccac
     3421 tcccatataa ctgaagtcgg tgatgtaatc gaaataccat tcatcattgc gtgaaataag
     3481 ccgtatttcg acaggatggt aaccgccctt ttcagtgctg taacactggt ctttaaataa
     3541 cagactgacg gctgtaattt tggctttatg cggcggtgga tttcccgctt catttattat
     3601 aatatttatt aattcctgat cgacgggcat agctagccct tcctgacgga tagcactcat
     3661 cgtttttatt ccggtaaata tgcatttgaa ttgatgatac aaacaaataa ttgcccatac
     3721 tgactcttca gacgatagac gtcctcccat caggatagaa taataaaatg aaatgctaag
     3781 ttgcaatcag tttgtatcag ctactggaca atatgaaact atccagcaat gttattttac
     3841 cagggtcatg cttttaatgc aaataatttc acccggaaac tatttttgtt tttattttat
     3901 aaactcatct aaaaacataa ttaagctttt cctcttaggg ttatccagct tattccagac
     3961 ttgctcgagt cgttgtttta attcaacgtc aagcccagtg gcatagttaa tcgggatatc
     4021 agaaacattc aaatcctcca tacaatcaat aaagaaccag cttattggag tttttaaagc
     4081 aacagcaatt ttgactaaat gagcaatatt gatcttattc gttccgcgtt catagcggga
     4141 aagttgttgt tgagagatat cgatagtctc tgcaagatcg gcagcagtta gccctgcttc
     4201 tttacgtctg gtctgaatac gctgccctac cagcttatca gctgaatctg ccatcagttt
     4261 aaccatcact ttatctccag aacgtccata agaggaattc tggggctttt ttactcttgc
     4321 atgaacatca ctaatggaca taaaattaac tatcacatca tttatagaca aagatacctg
     4381 caaccgaaca actaagctgg attggaagcc cactcagttg agcagcagag caaaggtggc
     4441 aaaaaggaga acattgtggc aaccaccatt actgagataa tggaatgctt tgagtatttt
     4501 ttcagttctc tttatcgccg ggagttcgtc aaaacactgc gtctgaacga atgtagcgag
     4561 cgggaattac tgcctctggt acgttgctat ttgctgggtt ggtttgcaga taacgtctca
     4621 ccggaagtaa aaagcaaact gccaggaact gtatccgggc acggttacat tgattttgtc
     4681 attgatgatg tagccgttga gtttgcagta cgtaaaccaa ctgcggcacg ttccaatgtc
     4741 tccgcgaccg tcaacagtac agaagtaaag aaattgatga agcacgatgg caaagccttg
     4801 cttgtgctgt ttgacttctc tgacgcgcct tattcagaag aacagattga gtccttccgc
     4861 aactggcctt ctcttggtcg agggaatcat cgcaagtccg cattcaacgt cgtttatttc
     4921 tttgtggaaa aacgcagacc tctggcactg gggaaaatca ccaaaaacat ccgtatcact
     4981 taacagggaa ttaattaatg aacagaaaac tgttggcctt attgatggca gccataacgc
     5041 tacctgtcgc ggcagcgcag tacgtaaaac ccggagcggt tctaaccctg aatccgggaa
     5101 agggcaatgc tgaattcaac attaatgcct caacagggga tggttcgggc gtatgcaata
     5161 tggatggtac ggcacagcaa atagctgccg gagaaagcca gaaacgtcgc tgggtctgga
     5221 atgacaatgc cagccagtgt gttgcagtaa ttagtgaact gaaaaacggt aaggccagcg
     5281 ttatgactcg tggttgcgaa ggttactgcg gagcccccgc aacaggtgca atggatggtc
     5341 tgtttaataa gaaataaaag tatagttaat taacgaagga actatagatg aaaagaacaa
     5401 tgcttctggt attaatagca gctggtttgc tggctggttg cggcgagaaa acgccaaaat
     5461 gtagtagtga cgatgcaaaa aatcttgtcg tagatattgc cagaaagacc atcgagaaag
     5521 gtatgacgct ggataaggat gtgcgtattt ctgtagaaaa tgtcagaaca attagctatg
     5581 aatcaggtct ggatgtttat cagtgcgcgg ctgatttaac gttcacaaaa cctgacctgc
     5641 aaaattccct accaatcacc tatcggattc agaaaactga tgaaggtaaa ggtcagtcct
     5701 atataaacgt atcaggctta taatcaaaag acttgtatca cctgctcgca ccattatcta
     5761 atatggcgcg ggctttaaaa ttttctatag aaattggaat atcaaattat tcaagcaatg
     5821 tatgaaattt cgatttatct catcatggaa actggagcgc ttctgcatca cagcaagcgg
     5881 tcaagagcac accgattgac cattagtaat tcaaagcttg ccaagttcct cctccagccg
     5941 tgcggcctcg ggtacaccga gcgcgacaag tgatgcgacg aagttgtcga tggcaggccg
     6001 cagcggtgcg ctattactga aactacaagg gctacgtccc agtatagcct ccatcaccaa
     6061 gcaccatcgg cggcccacgc cgtagtcaat ccatagttgt tggaaatcag gatagacctc
     6121 aagccataca catacagccc caacgagcat attcagttgt tcagcccggg gcgcaacctc
     6181 aagtaagttg agtaacaaca atgcgacgaa cggtgacggc cctttgctga ctaatttatc
     6241 cagaataggt aaaaacggac caattcgatc cattcctttc tcaagtagat agcatttcga
     6301 tcccttccca aacatttggt cgttgaagaa caacactgcg attgccgggc caaggtgcat
     6361 ttcgattgac aagtccctgc tccggttgag acgcccccat ccacgcgtgg tgagcatatg
     6421 gtcaacaagt actttgcgaa catctatggc aatctgcgtc ggaatactat tgccaccaaa
     6481 gtaaaccaca tcgaagttgc gcaaaaaatc gacgagtacg tcgtagaaat tctggtctgg
     6541 gagagtaatt atgtgctgta cgactaactc aatgacttca gacgacgata gcccgacaac
     6601 gcaacgcgca gccaaatcaa agaatgtatt gttccattca gatggaggct gatccgtttc
     6661 atctccgtcg tctaggtttg ctccatttgc gacgatcgtc cacggcatgt aggatttcac
     6721 gacttcgctg agccaggaca gcgcagcatc ctcggagaca atattcactt ggcgtagcca
     6781 gagtgccgcc gcctgatgat ctgcatgcac ttttggtggg gcaattgaca cttctggctg
     6841 ctttgatgca gccatgctaa cttctcgcaa gcgtagtcgc cttcccggcc gtgcgcgctc
     6901 ttctggaaaa actggccaca atggctccgt cccatcgctg ttaagccatg agatctcggc
     6961 ggcaacggct gcccgtgctc gttcgtggct gcgcgcttta cgagcttcta cttcttcctc
     7021 cgacgcatcc caaacccgct cctcaacaac acaagcgctg aatgcacatc ggagaataga
     7081 tctcggaaga cgactatcga cggccgcgag gactgagacg gacgtcccta agccgtgcgc
     7141 ggcagcgtga tttcccctag ccgctacctc aagaagtgac cgcacatctt ctgttgttga
     7201 tcgatgtcgc aaggcgtgaa tcaatccagc ataggcgatt gcagtcggat tgaagcgaag
     7261 gccccctcgc atctgacgca caggattgtc gtcaagcgcc acaagcgtct tgcccagttg
     7321 cgaccgagcc cattctccgt gttcagcata caaggcatca ttaccatccc gcatcacgat
     7381 catggcggcc gccacaaacg cttcctcttg catccaacgc tcgtcgtcat cgtcgtcgga
     7441 ttcaatgtct gtcgtagcca tcgccaaacg tcgtgcccaa gctacagcca ctattcgacc
     7501 ttccggcagt aactgagatg gatcgtcgat cgcgagtgtc aacacagagc atgtggcgaa
     7561 atctgactct cgctcggttg cggcatcgcg caaagcctgt agatgggttt gctctgccgg
     7621 aggtgataca tacttgcgcg cagtcgtgga tgaaccgtcc ttgagagtca tttcaaattc
     7681 ttgccaattt gtggcatctg atagattcag cgcataccga accataaatt ccgggcttct
     7741 gagattagag ctcgcgacgg gttcgcctaa acgagccgcc tcgctcacca gcagcatcct
     7801 cagcgcggta cgttgttcca aagatgcttg aaacgtgaaa gaaccaatca gttcgtcaag
     7861 agtagtccgt ctggatgagc gacgctgaag atcagccgca atcatattac cttgcgactc
     7921 gctacgcgca gtgttgagat cgaagaattc gggtatttcg actctatcat gcacctgacg
     7981 tatgcgatct aagcacagca gttcgggaca gccgagaaaa gccgtggcta tcctaagcga
     8041 tttgggccaa tgcgagatga tgagatcaac tcccaccaat aagtacgcag cgcatgagcc
     8101 tggcggacca agaacatctg ttagtacatc ttcaaatgct tcacctgcat ctacgcggcg
     8161 atgagcccac gcttcaagtg ccataagcga ggatgtaacg gcgtagaaat tactgttgcg
     8221 tgaccagaag taagtctgac tccatgggaa cgtgcgcaca cccttcggca agaccagctt
     8281 gaatccattt atcccagaat cggctccttg gctctcatgt gcgactgcgt gtgtaaccaa
     8341 gcgatggatc agagccaggc cgttcttggg tgagttaatc aataaatcga gaaatgggcc
     8401 ttggtccggg gataccggaa ggaatacgtg atcgagatag gtaaacgcct cttcgcgttc
     8461 cgtgccgaag tggcgcttgc gtccccgggg acccgagatc aacgcctgtg cggttaaatt
     8521 ggccagttca actggggctg cttgtgccaa cgtgccgcgc atcttcaaga tactgcgcac
     8581 aatatattcg ttgtgttcgc aacttcccac tgctgtcagg tattcggcag ccaattccgg
     8641 tgttgtacgt gcaaatatga tgaacgcatc gcgaaggtca gatttaagag actgagtacc
     8701 attccgatca agatgccccc tgaacaaagg ctcttcaccc ggcaaaagca tctcgtttct
     8761 tggctctaac agccgtagcc aaccgtatat ctgtcgtgtt gtaagggccg tgatatcggt
     8821 aatgccaagt gtaccaatgg aaaatgctgt gtatagctgg acgatgtcgg gaatagcttc
     8881 aattggagct atttccgcag tgtccaacag ccaggtaatc aacgctatcc atgctggacc
     8941 gcgtgggata ttgactgatg ggggtatcag tgctgggtcc actcccgcag cagcaaagac
     9001 ttttgcagcc ggaagtacat cgacagccat gacgattcgg atgagttccc gcaacaatgc
     9061 ggccctattg gcaagaagtt caggtgatgc acgactgaga agtgtttccg cagcctctga
     9121 ccgagctaat gcgagcaacg cagctcggcg ccaagactga tgcactccca cctggcttaa
     9181 acgctcaaca atcgcgagcc actttacacc atcaaccgcc cgctcgaccg ccatacgagc
     9241 tgccaactca attccacgag caaacatcgc ggttgccggc cgatctagtt gtaaaccgtc
     9301 aataagcctt gggtcagagt gaatggcatt cgcgatcgcc cactctcgca gtacatcatg
     9361 gcgaaatgcg acgaggtcgg tgcttagatt tcgcagcgtg ccactggaca ctaaggcatc
     9421 gatcgggata gcactgtgac attttatatc gagaaagtcg gcaccagaca aaatctgaaa
     9481 agccaagtcc tgcagtagcc gagagcgatc acgccaaccg gcatcacgtg taccatccgc
     9541 attaatccac cattgctcgg ccatatctac ttcggtacgg ggcatcggct cagatgcggt
     9601 ctggcttgct agacgtgaga ggcgaaataa gttcctcgcg acctgacgtg cgggatgacc
     9661 ttcggtgaga aggggcgcaa gagaaggatc aatcgctttt agctgttcga cctctgcctt
     9721 actcagctca tcgataatga ttggttcagt tagtcccaaa cgcgctagtg catcgtttgg
     9781 tagccaattg ggctcatcga gcccagactc aagccgcgct gtcgctacaa tgaccaagcc
     9841 tggaacgata gatgcttcgc tgacaatatc tacaacggtg agcctctctt ctgcattgaa
     9901 aaaatcgagg ttatcgatat atatcgtggc tccaccgtcg tttgcaagct cgacaagtaa
     9961 ctcacgtagc gtaccgtcga agcctagctg tgcacgccat gccacccacc cacggggaac
    10021 gcatcgccct gggctgagta caatgaccgg cccctcagtt tgcatggctt cggccatctg
    10081 ccgtaggatc cctgattttc cgacccctgc atctccacgg atctctacat agcgcccaag
    10141 ccccagtgct gcatgtatag cggcaacacg ctcctgccta gcaaggactg ctttaccaac
    10201 tcgattacga atatcagcaa gagccaaacg tgaagactca gtcaatgcag cacgggccgc
    10261 catgtggcgt cgctcaccta agaaccgata gccaaattgt gcaagtgtca ctagtgccgt
    10321 gtcgcgggtt ttgtctccac cgctttttgc cacatcgatt gaaagttcaa taagactgcc
    10381 ccaaaaggcc ccaacacgcg atccgtcatc agcatggagg atacgaaggg cccgttccag
    10441 tgccaagtca tgcgatgcag agccgggtgc cgtaaaatcg aaggtcaaaa tttggatccg
    10501 acgcagcaaa aaccaaacag tttcattgtc gtcgggcgaa ccttcatcaa gtaaatgggt
    10561 tttgaacgtc ttgacgaatg agcgcatatc gtcgttcgct acaccagcca gatcaatttg
    10621 tgcggcgaac gtagttgcgt cgctaatttg gcgggctagt gtgagtacgt cttgatatgc
    10681 tccatctatc ttgcgagacc ctttagtcgt cgcgatcgct aactcgtatc gctgggttga
    10741 aaaatcaggt cgttgagaag ctttgacgat ttggcccacg actttacgaa agaccggatc
    10801 agaagcggcg aaggtgatag accgcttaac ctgaacttcg agaacagcca ctttcccgga
    10861 aatattgtca tgcccgtgaa tgatcacgtc atcaagcgga taccccgcgt tggcctgttg
    10921 caaggctact cgatctattg acgcaccggg aaggccacgt gcaggggcac cagcgagcat
    10981 ggctagcatg tacgacgccg caacttgggc ctcaaaatga gtacctgcag gcccactggc
    11041 aagcgtgctt gtccctgggc ttttatcctc aggtaacgtg tgctgttctc tcatgcttct
    11101 tcctttcgaa gctgtcgccc attgtttatc ttgcgctgac ccagccttta actattggca
    11161 tacctatcga cattatattt ttttacccaa tcgatgtgca ctaaattctc ttccaaacaa
    11221 agattcaaac atccttaatg atcttgctaa ccagctatcc aaatcttggc tcttgtaata
    11281 tcgaaaatgg tctcgtgctc aaggagcacc gatagcgata gacactcgta tacacgacct
    11341 ggactgaccc cacgcggtct tcgtcatgtt tagatggccc caaatccaag ttgtaacagg
    11401 tctggactac atccactcga ttgtgcattg acgctcatct tttagacaga tattgtggtg
    11461 tcatattaaa aatatgaggt tttgtaatga atgagctcct tttaccagag caagttaaag
    11521 ctgcaagagc tcttctcgct tggtctcaac aagaactggc ctccaaagca aatgtggcaa
    11581 catctacact tgcggatttt gagcgtggct ttcgtactcc agtagcaaat aatgcccaag
    11641 ctatccgtga tgccttagaa gctgaaggtt tgcagtttat agctggtggg gtagttgaaa
    11701 ggggtatgct gcagccacct gaaaatgtaa aacctggttc tttgatgcgc tggattaatg
    11761 caactcacct ttcacagtgg ggtgaacgga gagatggtca gagtggtatt cctgaattat
    11821 tacgacgttt aatttttgca acagtaggtc ctgccgcaaa agttcatttc ccatcagatg
    11881 agagtgtgca atatcctggt tgggatggtg agtgtaaaac gagtttgggt ttgggcttcg
    11941 ttcctgaggg tgattctgtt tgggaaattg gtgctcaacg tacctctatc cgcgctaagg
    12001 cagaagaaga ttttaataaa agatctggga atccactcgg gtatagtcca gataaaacaa
    12061 cgtatgtatt cgttactcca caacgctttc ctggtaaaaa taagtgggta gaggagaaaa
    12121 aagctctcaa tatttggctg aatgtctgtg ccattgatgc tgatgatctt gtccattggt
    12181 tagaaattta tcctgcggtc gctcagtggt tgtcagtaaa aataggtcat cggccacagg
    12241 gattgcgtaa tattgaagag tcatggagcg agtggattca cgcaacgaga acacctctca
    12301 ctcccgatgt tatcttggcc ggacgtgatg aagaacaaac aaaagtcctt aggtggttaa
    12361 gagattcacc gcaacaactc tcggtgcaag ccgaagctcc cgatgaagca ctagcttttc
    12421 tttatgcatc tataagtcct ctgcctgaag agcataagct gttctattgg agcaaatgtg
    12481 tcgtagttga caacgcaaca acagcccggc aattagctgg tttaggcacg ccattaatca
    12541 ttgttctcac tatttcagaa ccggggattg cacaatctct tgttaataat ggtcaccatg
    12601 tctacgctat ctatggctca gatgtgtctc atctatccgg tcattcaata cgccttcctc
    12661 gcccatggag atttgagcta aaaatagcat taactcatgc tggattaaat gaggaggatg
    12721 ctcatcgtta tgcccacgca tcaggccgca gtattacggt attaaggcgc ttaatgccca
    12781 tagccccaaa ctataaacca caatgggctg aacatgtttc atctgagctt attgccgcaa
    12841 tgttcgcggg gagctgggat gaaacctcat ctcaagatca aaaaattatt agtgatttag
    12901 ctggttgctc ttatgagcag gtagaagaaa tcttggcacc gttagcatcc acttttggtg
    12961 gtccattaat tcgctctggt aatctttgga aagtagtttc attacgagat ctttggactc
    13021 aagtaggtaa tcagctaact tcccaccaac taaagcgctt tgagaataca ttccattcgg
    13081 tggtgagcgc cattgatccc cattttgaga ctcaacctaa tgccgatacc ttctatgaag
    13141 ataatagcgt agggaaacca tcaggtagca tcagacgtgg cttaacagaa tcgatgattg
    13201 ccttggctgt tttcccagag gtagcaacgc ttattacgga tgtatcttct catgtgaata
    13261 gtgcggtgta taagttgctt aataatgcaa ctgagccact ttggtggtct ttgtctcagg
    13321 atttccataa tcttgcagaa gcagccccaa cggtatttct agacgctgta gaagctgggt
    13381 tggaaggcga ttcacctcag attttgtcat tattccgaag tgatgaaggg ataatgcatc
    13441 ccacagagta tctttcaaat ttgttatggg cattagagat gttagcgcgt agcccgcgtt
    13501 atctaatgca atctgcactt ttactggctt ggttagatga tgttgatccc ggaggtcgat
    13561 ggggaaaccg tccagcagtt tctttaaggc ggatttttgt tagttggtca ccacaaactt
    13621 atgctaattc atcacaacgt attaaggtca ttgatcggat catatcgctg catccaattg
    13681 ctggttggaa gttattgctc gcattagcac ctcgttcaca cgatacttca gaaccttctt
    13741 ctatgccaaa ttggcgtgat ttcactccta atgagccgga gtcgattacc tggtcctctg
    13801 ttgcaacagc agcatgtgaa atcggtgaaa gattattaat gcatataaat gggaggtgcg
    13861 aacggtggtt tgaacttttc cacctttggg ggaattttga ttcaaactgg aaattttcag
    13921 cagctaagca attagctgat tactccctga acctcacatc ttctgatgaa aaagaaaggt
    13981 tgtggaatga gttacggcat tttttacaga gaaaccgtgg cttcaaagat gctccatggg
    14041 ctctgtctga agaagaatta gcaccgttgg atgctatatt tctttcacta acaccagaaa
    14101 atgtcgagga gcgttttcgc tggctatttt gtgcaggggc caatgagtta ggcgaaaatt
    14161 atgattggca aacacaacga aataggctcg aagagagaca attggaagca gtagagttct
    14221 tacttgcaga acttgaattt gaacaaatat ttcatttctc ttcaacaatt acgctgcact
    14281 ccgattttgg tcttgcttta gcgcgatcct caacaaagtg tgggcataaa cattttctaa
    14341 tgaaaaaagc tctaatgtct ggtgattcag atatagcaaa tattggtttg ggaattcttt
    14401 atggactcaa agccacgaaa ggctcagaaa gcgaaacttg ggttcaagaa atatgggaac
    14461 aagctataac tgataattgg ggggagttag cggaagtacg catttcccaa gtattaccac
    14521 ctgtaatgtc gctttggctg aaaatagaat cgagaccagt taatattagt acaatatatt
    14581 ggcagacgat ccctacattt aggctttctg cagatttaga gcttgagtat gtcattgacc
    14641 atttacttct ggcagaccga agtcacgatg ctcttgcgtg gcttgctaat aatataaaaa
    14701 tagaaccaga aggctcagtt attattagag taatgcatac cgctgcaagc actaaagact
    14761 ctcccaataa tgataatacg atgtcgagct attatattgg tattctccta gattacctgg
    14821 agagtgatgt aaatacttca aaagaagaac ttgtgaggct cgaatggatt tattttcaag
    14881 ttttacggca ttcacgacat ccagccagaa acttacatca ggctcttgct aaagaccctg
    14941 tattttttac ctcactaatg aaattactct atctacctga agaagatagt ggtgtagttg
    15001 aatctgaacc ggcaaatcct aagcaggccc gtgatctagc aagccaggca tatcaagttt
    15061 tgcatgattg ggcaattgta cccgggaccg atgagaacgg tactattgac tcttatgcat
    15121 tgatgtcgtg ggtcaagcaa gctcgccaat tactgaagtc tgcaggtcgt ggtgaaatag
    15181 gtgatgacaa gattggcatg attctctctg ccgcaaaaag aaaaaaaaat gaaacgtggc
    15241 caccagaagc aattcgcgaa gttcttgagt ttgctagaag tcgagcaatg gagagtggtt
    15301 ttgaagttgg tgtttacaac cgccgtggcg taactgtacg catgccacat gatggtgggg
    15361 ggcaagaacg aatattagta gaacgctata aacaagatgc tgatgatctt agatttgaat
    15421 ggcctcgaac cgcagcgtgc ttagaccgca ttgctataag ctatcaacaa gatgcaatta
    15481 gagaagatca tagtgcggac caaggtgatt ggttataaac catcttatca taattgtatt
    15541 tattgagttt tttaaatatg caaaggagat tacatgcaaa gaaatttatt aaaatcctct
    15601 acagacaaaa taaggaaatg
//
LOCUS       DADXDL010000106        14823 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.106, whole genome shotgun sequence.
ACCESSION   DADXDL010000106 DADXDL010000000
VERSION     DADXDL010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14823)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14823)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14823
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.106"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(154..1206)
                     /gene="fbaB"
                     /locus_tag="IRB70_004044"
     CDS             complement(154..1206)
                     /gene="fbaB"
                     /locus_tag="IRB70_004044"
                     /EC_number="4.1.2.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006820796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I fructose-bisphosphate aldolase"
                     /protein_id="HBC0633896.1"
                     /translation="MTDIAQLLGKDADNLLQHRCMTIPSDQLYLPGHDYVDRVMIDNN
                     RPPAVLRNMQTLYNTGRLAGTGYLSILPVDQGVEHSAGASFAANPLYFDPKNIVELAI
                     EAGCNCVASTYGVLASVSRRYAHRIPFLVKLNHNETLSYPNTYDQTLYASVEQAFNMG
                     AVAVGATIYFGSEESRRQIEEISAAFERAHELGMVTVLWAYLRNSAFKKDGVDYHVSA
                     DLTGQANHLAATIGADIVKQKMAENNGGYKAINYGYTDDRVYSKLTSENPIDLVRYQL
                     ANCYMGRAGLINSGGAAGGETDLSDAVRTAVINKRAGGMGLILGRKAFKKSMADGVKL
                     INAVQDVYLDSKITIA"
     gene            1463..2740
                     /locus_tag="IRB70_004045"
     CDS             1463..2740
                     /locus_tag="IRB70_004045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0633897.1"
                     /translation="MKTTAKLSFMMFVEWFIWGAWFVPLWLWLSKSGFSAGEIGWSYA
                     CTAIAAILSPILVGSITDRFFSAQKVLAVLMFAGAALMYFAAQQTTFAGFFPLLLAYS
                     LTYMPTIALTNSIAFANVPDVERDFPRIRVMGTIGWIASGLACGFLPQMLGYADISPT
                     NIPLLITAGSSALLGVFAFFLPDTPPKSTGKMDIKVMLGLDALILLRDKNFLVFFFCS
                     FLFAMPLAFYYIFANGYLTEVGMKNATGWMTLGQFSEIFFMLALPFFTKRFGIKKVLL
                     LGLVTAAIRYGFFIYGSADEYFTYALLFLGILLHGVSYDFYYVTAYIYVDKKAPVHMR
                     TAAQGLITLCCQGFGSLLGYRLGGVMMEKMFAYQEPVNGLTFNWAGMWTFGAVMIAII
                     AVLFMIFFRESDNEITAIKVDDRDITLTQGEVK"
     gene            2737..3741
                     /locus_tag="IRB70_004046"
     CDS             2737..3741
                     /locus_tag="IRB70_004046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribosylglycohydrolase family protein"
                     /protein_id="HBC0633898.1"
                     /translation="MKTERILGALYGQALGDAMGMPSELWPRSRVKAHFGWIDRFLPG
                     PKENNAACYFNRAEFTDDTSMALCLADALLEREGKIDPDLIGRNILDWALRFDAFNKN
                     VLGPTSKIALNAIRDGKPVAELENNGVTNGAAMRVSPLGCLLPARDVDSFIDDVALAS
                     SPTHKSDLAVAGAVVIAWAISRAIDGESWSAIVDSLPSIARHAQQKRITTFSASLAAR
                     LEIALKIVRNADGTESASEQLYQVVGAGTSTIESVPCAIALVELAQTDPNRCAVLCAN
                     LGGDTDTIGAMATAICGALHGVNAIDPALKAELDAVNQLDFNRYATALAKYRQQREAV
                     "
     gene            3738..4703
                     /locus_tag="IRB70_004047"
     CDS             3738..4703
                     /locus_tag="IRB70_004047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBC0633899.1"
                     /translation="MSGARLHTLLPELATRQPVMVIGAAVIDVIADAYALPWRGCDIE
                     LKQQSVNVGGCALNIAVALKRLGIEAGNALPLGQGVWAEIIRNRMAKEGLISLIDNAE
                     GDNGWCLALVEPDGERTFMSFSGVENQWNRQWLARLTVAPGSLLYFSGYQLASPCGEL
                     LVEWLEKLQDVTPFIDFGPRIGDIPDALLARIMACRPLVSLNRQEAEIAAERFALSAE
                     ITTLGKQWQEKFAAPLIIRLDKEGAWYFSNDASGCIPAFPTQVVDTIGAGDSHAGGVL
                     AGLASGLPLADAVLLGNAVASWVVGHRGGDCAPTREELLLAHKNV"
     gene            complement(4677..5423)
                     /locus_tag="IRB70_004048"
     CDS             complement(4677..5423)
                     /locus_tag="IRB70_004048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBC0633900.1"
                     /translation="MEQAHTQLIAQLNERILAADNTPLYIKFAETVKNAVRSGVLEHG
                     NILPGERDLSQLTGVSRITVRKAMQALEEEGVVTRSRGYGTQINNIFEYSLKEARGFS
                     QQVVLRGKKPDTLWVNKRVVKCPEEVAQQLAVEAGSNVFLLKRIRYVDEEAVSIEESW
                     VPAHLIHDVDAIGISLYDYFRSQHIYPQRTRSRVSARMPDAEFQSHIQLDSKIPVLVI
                     KQVALDQQQRPIEYSISHCRSDLYVFVCEE"
     gene            complement(5475..6293)
                     /locus_tag="IRB70_004049"
     CDS             complement(5475..6293)
                     /locus_tag="IRB70_004049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416605.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 25 protein"
                     /protein_id="HBC0633901.1"
                     /translation="MQLRITSRKKFTALLCALGLISIVAIYPRQTVNFFYSTAIQIKD
                     YIHFYGYRPVKSFAIRIPASYTIHGIDVSRWQERIDWQRVAKMRDNGIRLQFAFIKAT
                     EGEKLVDPYFSRNWQLSRENGLLRGAYHYFSPSVSASVQARLFLQTVDFAHGDLPAVL
                     DVEERGKLSAKELRKRVSQWLKMVEKRTGKKPIIYSGAVFYHTNLAGYFNEYPWWVAH
                     YYQRRPDNDGMAWRFWQHSDRGQVDGINGPVDFNVFNGTVEELQAFVDGIKETP"
     gene            complement(6358..7158)
                     /gene="thiD"
                     /locus_tag="IRB70_004050"
     CDS             complement(6358..7158)
                     /gene="thiD"
                     /locus_tag="IRB70_004050"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBC0633902.1"
                     /translation="MKRINALTIAGTDPSGGAGIQADLKTFSALGAYGCSVITALVAQ
                     NTRGVQSVYRIEPDFVAAQLDSVFSDVRIDTTKIGMLAETDIVEAVAERLQRYQIQNV
                     VLDTVMLAKSGDPLLSPSAVATLRSRLLPQVSLITPNLPEAAALLDAPHARTEQEMLE
                     QGRSLLAMGCGAVLMKGGHLDDGQSPDWLFTREGEQRFTAPRIMTKNTHGTGCTLSAA
                     LAALRPRHTNWADTVQEAKSWLSSALAQADTLEVGHGIGPVHHFHAWW"
     gene            complement(7155..7943)
                     /gene="thiM"
                     /locus_tag="IRB70_004051"
     CDS             complement(7155..7943)
                     /gene="thiM"
                     /locus_tag="IRB70_004051"
                     /EC_number="2.7.1.50"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyethylthiazole kinase"
                     /protein_id="HBC0633903.1"
                     /translation="MQVDLLSSAQSAHALHLFHKHSPLVHCMTNDVVQTFTANTLLAL
                     GASPAMVIETEEASQFAAIASALLINVGTLTQPRAQAMRAAVEQAKRSQTPWTLDPVA
                     VGALDYRRRFCLELLSHKPTAIRGNASEIMALAGVANGGRGVDTTDAAANAIPAAQTL
                     ARETGAIVVVTGEVDYVTDGHRIVGIHGGDPLMTKVVGTGCALSAVVAACCALPGDTL
                     ENIASACHWMKQAGERAVARSEGPGSFVPHFLDALWQLTQEVQA"
     regulatory      complement(7978..8074)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(8166..8438)
                     /gene="rcnR"
                     /locus_tag="IRB70_004052"
     CDS             complement(8166..8438)
                     /gene="rcnR"
                     /locus_tag="IRB70_004052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II)-binding transcriptional repressor
                     RcnR"
                     /protein_id="HBC0633904.1"
                     /translation="MSHTIRDKQKLKARASKIQGQVVALKKMLDEPHECAAVLQQIAA
                     IRGAVNGLMREVIKGHLTEHIVHQGDELKREEDLDVVLKVLDSYIK"
     gene            8559..9362
                     /gene="rcnA"
                     /locus_tag="IRB70_004053"
     CDS             8559..9362
                     /gene="rcnA"
                     /locus_tag="IRB70_004053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nickel/cobalt efflux protein RcnA"
                     /protein_id="HBC0633905.1"
                     /translation="MTEFTTLLQQGNAWFFIPSAILLGALHGLEPGHSKTMMAAFIIA
                     IKGTIKQAVMLGLAATISHTAVVWLIAFGGMVISKRFTAQSAEPWLQLISAVIIIGTA
                     FWMFWRTWRGERNWLENMHEHEHEHEHDHEHHHHHEHGEYQDAHARAHSNDIKRRFDG
                     REVTNWQILLFGLTGGLIPCPAAITVLLICIQLKALTLGATLVVSFSIGLALTLVTVG
                     VGAAISVQQVAKRWSGFNTLAKRAPYFSSLLIGLVGVYMGVHGFMGIMR"
     gene            9581..9919
                     /gene="rcnB"
                     /locus_tag="IRB70_004054"
     CDS             9581..9919
                     /gene="rcnB"
                     /locus_tag="IRB70_004054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416610.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ni(II)/Co(II) efflux transporter accessory
                     subunit RcnB"
                     /protein_id="HBC0633906.1"
                     /translation="MTIKNKMLLGALLLVTSAAWAAPATAGSTNTSGISKYELSSFIA
                     DFKHFKPGDTVPEMYRTDEYNIKQWQLRNLPAPDAGTHWTYMGGAYVLISDTDGKIIK
                     AYDGEIFYHR"
     gene            complement(10001..11035)
                     /locus_tag="IRB70_004055"
     CDS             complement(10001..11035)
                     /locus_tag="IRB70_004055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0633907.1"
                     /translation="MMFRNGMLLIFILWVNFTWAGCRTTASLNITDSINVGEILANEV
                     SFSKNVVFTGISCDTSTDKIVYKNIQSDWVEVGPFGNGEKLKVKIESLGKNSETIGKS
                     SNAQAELPYVVKIARGTLDFSGERKPTWFLSDTVIANIGGESSTSIDFWLGVCKALKI
                     NWCVNYLTSKLAGDTFTLGLSISYYPKNTTCKPQNTIIKVDDIALPQLRSQGKITANS
                     KEGIISLKCDNLFGDKNQASRNMVVYLSSSDLVTGSNTILRGNIDNGVGFVLDLKEPS
                     KGTEAAIKISASGNQGAATSLWKTDKPGASLNSNIINIPVMASYYVYDTNKVKSGALE
                     ATALINVKYD"
     gene            complement(11046..13526)
                     /locus_tag="IRB70_004056"
     CDS             complement(11046..13526)
                     /locus_tag="IRB70_004056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBC0633908.1"
                     /translation="MLRMTPLASAIVALLLGIEAYAAEETFDTHFMIGGMKDQQVANI
                     RLDDNQPLPGQYDIDIYVNKQWRGKYEIIVKDNLQETCISREIIKRLGINTDNFASGK
                     QCLTFEQLVQGGSYTWDIGVFRLDFSVPQAWVEELESGYVPPENWERGINAFYTSYYV
                     SQYYSDYKASGNSKSTYVRFNSGLNLLGWQLHSDASFSKTNSNPGVWKSNTLYLERGF
                     AQLLGTLRVGDMYTSSDIFDSVRFSGVRLFRDMQMLPNSKQNFTPRVQGIAQSNALVT
                     IEQNGFVVYQKEVPPGPFAITDLQLAGGGADLDVSVKEADGSVTTYLVPYAAVPNMLQ
                     PGVSKYDFAAGRSHIEGASKQSDFVQAGYQYGFNNLLTLYGGSMVANNYYAFTLGTGW
                     NTRIGAISVDATKSHSKQDNGDVFDGQSYQIAYNKFVSQTSTRFGLAAWRYSSRDYRT
                     FNDHVWANNKDKYRRDENDIYDIADYYQNDFGRKNSFSANMSQSLPEGWGSVSLSTLW
                     RDYWGRSGSSKDYQLSYSNNLRRISYTLAASQAYDENHHEEKRFNIFISIPFDWGDDA
                     TTPRRQIYMSNSTTFDDQGFASNNTGLSGTVGSRDQFNYGVNLSHQHQGNETTAGANL
                     TWNAPVATVNGSYSQSSTYRQAGASVSGGIVAWSGGVNLANRLSETFAVMNAPGIKDA
                     YVNGQKYRTTNRNGVVVYDGMTPYRENHLMLDVSQSDSEAELRGNRKIAAPYRGAVVL
                     VNFDTDQRKPWFIKALRADGQPLTFGYEVNDIHGHNIGVVGQGSQLFIRTNEVPPSVN
                     VAIDKQQGLSCTITFGKEIDESRNYICR"
     gene            complement(13542..14216)
                     /locus_tag="IRB70_004057"
     CDS             complement(13542..14216)
                     /locus_tag="IRB70_004057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBC0633909.1"
                     /translation="MKGLLALLISSMVLPAHAGIVIYGTRIIYPAENKEVMVQLMNQG
                     NRSSLLQAWIDDGDTSLPPEKIQVPFMLTPPVAKIGANSGQQVKIKIMPNKLPTNKES
                     IFYLNVLDIPPNSPEQEGKNALKFAMQNRIKLFYRPAGIAPVNKATFKKLLVNRSGNG
                     LVIKNDSANWVTISDVKANNVKVNYETIMIAPLESQSINVKSNNANNWHLTIIDDHGN
                     YISDKI"
     gene            complement(14297..>14823)
                     /locus_tag="IRB70_004058"
     CDS             complement(14297..>14823)
                     /locus_tag="IRB70_004058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0633910.1"
                     /translation="AAAVFSSFFMSAGVFAADVDTGTLTIKGNIAESPCKFEAGGDSV
                     SINMPTVPTTVFEGKAKYSTYDDAVGVTSSMLKISCPKEVAGVKLSLITNEKITGNDK
                     AIASSNDTVGYYLYLGDNSDVLDVSAPFNIESYKTAEGQYAIPFKAKYLKLTDNSVQS
                     GDVLSSLVMRVAQD"
BASE COUNT         3651 a         3758 c         3447 g         3967 t
ORIGIN      
        1 aaaaacgaca atatgaaaat tgttcgagga gtgaaaggca aaaaaaacgg cctcccgata
       61 gggaagccgt agcaaagtgc gcgttatttt atgccggatg cagtgtaaac gccttatccg
      121 tcatacgtgg cagtgctggt cgtacaaagc acatcaggcg atagtaattt tgctatcgag
      181 ataaacgtcc tgcacggcgt taatcagttt cacgccgtca gccatcgatt tcttgaacgc
      241 cttacgtcca agaatcagcc ccattccgcc tgcgcgtttg ttgataaccg cagtacgcac
      301 tgcatcgctg aggtcagttt caccgcctgc agcaccgccg gagtttatca accctgcgcg
      361 gcccatatag cagttagcta actgataacg caccagatca atcgggtttt cgctggtcaa
      421 cttgctgtac acgcgatcgt cggtataacc gtaattaatc gctttatagc cgccgttatt
      481 ttccgccatt ttttgtttaa cgatatctgc acctatggtc gccgccagat ggtttgcctg
      541 accggtcagg tcggcggaaa catggtaatc aacgccatct ttcttaaagg cggagttacg
      601 caaataggcc cacagcactg tcaccatgcc cagctcgtgc gcacgttcaa aagccgcaga
      661 aatttcttca atctggcgac gtgactcttc cgaaccaaaa tagatagtcg caccaaccgc
      721 caccgcgccc atgttgaagg cctgctccac gctggcatac agcgtttgat cgtaggtatt
      781 cgggtaactt agcgtctcgt tgtgattaag tttgacgagg aatggaatgc gatgcgcgta
      841 acgccgcgat accgatgcca gcacgccgta agttgacgcc acacagttac agcccgcttc
      901 gatcgccagt tcaacaatgt ttttcgggtc aaagtagagc gggttagcag caaatgaagc
      961 tccagcagag tgctcaacgc cctggtcaac cggcagaata gaaagatatc ctgtgccagc
     1021 cagacgcccg gtgttgtaca acgtctgcat attacgtaac accgctggcg ggcgattatt
     1081 gtcaatcatc acgcggtcta cgtaatcatg cccggggaga taaagctggt cagaaggaat
     1141 agtcatacaa cggtgctgta aaaggttgtc ggcgtctttg ccaagcaact gcgcaatatc
     1201 tgtcattact atgctcccgt aaattccgat tggatatcgg ctatggattg tcctggcccg
     1261 ccttttgcgg gcaatcataa tcctggtcgt tacaggcgag tttttccatc ttttggatgt
     1321 tttttcagcg ttttctgttg gctcgattca tcagaaaaaa tgttaccgcg gtcaagtttt
     1381 caccgcaaag gtatttaaaa ggtattatta aatggtattg tcatcgcgta ccttacatta
     1441 cctgtcatga aggaattaaa agatgaaaac aacagcaaag ctgtcgttca tgatgtttgt
     1501 tgaatggttt atctggggcg cgtggtttgt gccattgtgg ttgtggttaa gtaaaagcgg
     1561 ttttagtgcc ggagaaattg gctggtcgta tgcctgtacc gccattgcgg cgatcctgtc
     1621 gccaattctg gttggctcca tcactgaccg ctttttctcg gcgcagaaag tgctggcggt
     1681 attgatgttc gctggtgcgg cgctgatgta tttcgctgcg caacagacca cttttgccgg
     1741 gttcttcccg ttactgctgg cctactcgct aacctatatg ccgaccattg cgctgactaa
     1801 cagtatcgct tttgccaacg tgccggatgt ggagcgtgat ttcccacgca ttcgtgtgat
     1861 gggcactatc ggctggattg cctccggtct ggcatgtgga tttttgccgc aaatgctggg
     1921 ttatgccgat atctctccga ctaacatccc gctactgatt accgccggaa gttctgctct
     1981 gctcggtgtg tttgcgtttt tcctgcccga cacgccgcca aaaagcaccg gcaaaatgga
     2041 cattaaagtc atgctcggcc tggatgcgct gatcctgctg cgcgataaaa acttcctcgt
     2101 ctttttcttc tgttcattcc tgtttgcgat gccactggcg ttctattaca tctttgccaa
     2161 cggttatctg accgaagttg gcatgaaaaa cgccactggc tggatgacgc tcggccagtt
     2221 ctctgaaatc ttctttatgc tggcattgcc gttttttacc aaacgctttg gtatcaaaaa
     2281 ggtattatta cttggtctgg tcaccgctgc gatccgctat ggcttcttta tttacggtag
     2341 tgcggatgaa tatttcacct acgcgttact gttcctcggc attttgcttc acggcgtaag
     2401 ttacgatttt tactacgtta ccgcttacat ctatgtcgat aaaaaagccc ccgtgcatat
     2461 gcgtaccgcc gcgcaggggc tgatcacgct ctgctgccag ggcttcggca gtttgctcgg
     2521 ctatcgtctt ggcggtgtga tgatggaaaa gatgttcgct tatcaggaac cggtaaacgg
     2581 actgactttc aactgggccg ggatgtggac ttttggcgcg gtgatgattg ccattatcgc
     2641 cgtgctgttc atgatttttt tccgcgaatc cgacaacgaa attacggcta tcaaggtcga
     2701 tgatcgcgat attacgttga cacaagggga agttaaatga aaacagaacg tattctcggt
     2761 gctctttatg ggcaggcgtt aggggatgcg atggggatgc cctccgagct ttggccgcgc
     2821 agtcgcgtca aagcgcactt tggctggatt gaccgttttc tgcctgggcc aaaggagaat
     2881 aacgcagcct gttattttaa ccgcgccgaa ttcaccgacg atacctcgat ggcgctgtgt
     2941 ctggcggatg cgttactgga acgtgaaggc aagatcgatc cggatctgat tgggcgtaat
     3001 attctcgact gggcgctgcg tttcgacgcc tttaacaaaa acgtactagg tccgacctcg
     3061 aagattgcgc ttaacgccat tcgcgacggt aaacccgttg ctgaactgga aaataacggc
     3121 gtgaccaacg gcgcagcgat gcgcgtctcg ccattaggtt gtttgcttcc ggcgcgtgat
     3181 gttgattcct ttattgatga tgtggcgctg gcctccagcc cgacacataa atccgatctg
     3241 gcggttgcgg gggcggtagt catcgcatgg gcgatttctc gtgccattga cggagaaagc
     3301 tggtcagcga ttgttgattc actaccctcg attgcgcgac atgctcaaca aaaacgcatc
     3361 actaccttca gcgcctcact ggcagcacgt ctggagattg cgctgaaaat tgtgcgcaat
     3421 gccgacggca ccgaatccgc cagcgaacag ctttaccagg tcgttggcgc aggtaccagc
     3481 actattgagt ccgttccgtg cgccattgcg ctggttgaac tggcacaaac cgacccgaac
     3541 cgttgcgccg tcctgtgcgc taaccttggc ggcgacacag acaccatcgg tgctatggcg
     3601 acagcaattt gtggcgcgtt gcatggcgtt aacgctatcg atcctgcgtt aaaggcggaa
     3661 ctggatgcgg taaatcagct tgatttcaac cgctatgcca cagcgctggc gaaatatcgt
     3721 caacaacggg aggcggtatg agcggcgctc gattacacac gctgctgcct gaattagcca
     3781 cgcgtcagcc agttatggtg attggcgcgg cggtcattga tgtgatcgcc gacgcttatg
     3841 ccctcccctg gcgtgggtgc gatatcgaac tgaaacagca gagcgttaac gttggcggct
     3901 gcgcactgaa tattgccgtg gcgttaaagc gcctcggcat cgaagcgggt aatgccttgc
     3961 cgctcggtca gggggtttgg gcggagatta ttcgcaaccg gatggcaaaa gagggcttaa
     4021 tcagcctgat cgataacgcc gaaggtgata acggctggtg tctggcgctg gttgagccgg
     4081 atggcgaacg cacttttatg tcattcagcg gtgtggaaaa tcagtggaat cgccagtggc
     4141 tggcgcgatt aaccgttgcg cctggcagcc tgctctattt ttccggttat caactggcct
     4201 cgccctgcgg cgaattatta gtggaatggc tggaaaagct gcaagacgtg acgccgttta
     4261 tcgattttgg cccacgtatt ggcgatatcc cggatgcatt gctggcgcgg atcatggcct
     4321 gtcgaccttt agtgtcactc aatcgtcagg aggctgagat tgccgccgaa cgttttgctt
     4381 tatccgcaga gataacaaca cttggcaagc aatggcagga gaaatttgcc gcgccgttga
     4441 tcattcgtct cgataaagag ggcgcatggt atttcagcaa cgacgcttct ggctgcattc
     4501 cggcatttcc aacgcaagtt gtagacacca ttggggcggg cgacagtcat gcaggtggcg
     4561 tacttgccgg gctagcctct ggtctgccac tggcggatgc cgtattactg ggcaatgcag
     4621 tggcgtcgtg ggttgtcggg catcggggcg gtgattgtgc gccaacgcgc gaggaactac
     4681 tcctcgcaca caaaaacgta tagatcgctg cgacagtggc tgatgctgta ctcaataggc
     4741 cgttgctgtt ggtcaagcgc cacttgcttg atcaccagca ccggtatttt gctatctaac
     4801 tgaatatgtg actgaaactc ggcatccggc atccgggcgc taacgcggga acgcgtacgt
     4861 tgtgggtaaa tgtgctggct gcggaagtag tcataaagag aaattccgat ggcatcaaca
     4921 tcatgaatta aatgcgcagg aacccacgat tcctcaattg ataccgcttc ttcatcgaca
     4981 tagcgaatac gcttaagcaa aaagacatta cttcctgctt cgaccgccag ctgctgcgcg
     5041 acttcttcgg gacatttcac gacacgcttg ttaacccata gtgtatcggg ctttttcccg
     5101 cgcaatacca cctgctgaga aaaacctcgc gcttctttca acgagtattc gaagatgttg
     5161 ttgatctgcg taccgtaacc acgcgaacgc gtcaccacgc cctcttcttc cagcgcctgc
     5221 atcgccttgc gcaccgtaat gcgcgaaacg ccggttaact gacttaaatc acgctcaccg
     5281 ggcaaaatat tgccatgctc cagcaccccg ctgcgcacgg cattttttac cgtttcggca
     5341 aacttaatat aaagcggcgt gttatccgcc gctaaaatac gttcgttcag ttgggcaatc
     5401 agctgggtat gcgcttgttc catttgtctt tttcctgcca gggagtctgg tgggagtata
     5461 tcactgcttc ttatttaagg cgtttcttta atcccatcaa cgaatgcctg caactcctcc
     5521 accgtgccat taaacacatt aaaatccacc ggaccattaa tgccatctac ctgtccacgg
     5581 tcggaatgct gccagaagcg ccaggccatg ccgtcattgt ccgggcgacg ttgataatag
     5641 tgagccaccc accacggata ttcattgaaa tagcccgcca gattggtgtg ataaaaaacg
     5701 gctcctgagt aaataattgg cttttttccc gtgcgttttt cgaccatttt tagccactga
     5761 cttacccgct tgcgtaattc ttttgccgat aattttcccc gttcttctac gtccagcacg
     5821 gcagggagat cgccgtgggc aaaatccacc gtttgcagaa ataatctcgc ctgaactgaa
     5881 gcggataccg acggggaaaa ataatgatac gccccgcgca gcaggccatt ttcgcggctt
     5941 agttgccagt tacgcgaaaa ataggggtcc accagctttt cgccttccgt cgccttaata
     6001 aaagcaaact gtaagcggat accgttgtcg cgcatttttg ccacccgctg ccagtcgatc
     6061 cgctcctgcc agcgcgaaac atctattccg tgaatggtgt aactggcagg aatgcgaata
     6121 gcaaaagatt tgactggacg ataaccgtag aagtggatgt agtctttaat ctgaattgct
     6181 gtcgagtaga aaaaattcac cgtctgacgc ggataaattg caacgatgga aattagccca
     6241 agagcgcata ataaagcggt gaattttttt cgactggtga ttctcagctg cattggtttc
     6301 atccctgaat gtcagcgcca aaggctgaca ataaccaaag cagctatagt acggtgctca
     6361 ccaccaggcg tggaagtggt gaaccggacc aataccgtga ccaacttcca gcgtgtcggc
     6421 ctgggctaac gccgatgaaa gccagctttt tgcctcctgt acggtgtcag cccagtttgt
     6481 atggcgcggg cgcagtgcag ccaacgccgc agagagcgta caaccagtgc cgtgagtgtt
     6541 tttggtcata atgcgcggtg cggtaaaccg ttgttccccc tcacgagtaa acagccagtc
     6601 cgggctttgc ccatcatcca gatgaccacc tttcattagc actgcgccac agcccatcgc
     6661 caacagcgat cgcccttgtt ccagcatttc ctgttcggtg cgcgcgtgtg gcgcgtcgag
     6721 caaggcggct gcttcgggca agtttggcgt tattaatgaa acctgtggca ataatcgact
     6781 gcgcagcgta gcaaccgccg aaggtgaaag cagcgggtcg ccgctttttg ccagcataac
     6841 ggtgtcgagt accacgtttt ggatctgata acgttgcaac cgttctgcca ccgcttcaac
     6901 aatatcggtt tccgccaaca taccgatttt agtggtgtcg attcgcacat cactgaacac
     6961 cgaatcgagc tgggcggcga caaaatcagg ctcaatgcga tacaccgact gtacgccacg
     7021 ggtattttgc gccaccagtg cagtaataac tgagcaacca taagcgccaa gtgccgagaa
     7081 ggttttaaga tcggcctgaa tccccgcacc accactcgga tcagtaccgg caatcgtcag
     7141 agcgttaatt cgtttcatgc ctgcacctcc tgcgtcaatt gccagagcgc atcaaggaaa
     7201 tgtggaacaa aactgcctgg cccctcgctt ctggcaactg cgcgttctcc ggcttgtttc
     7261 atccagtgac aggcagatgc gatattttcc aacgtatcgc ctggtagcgc acaacaggca
     7321 gcgacaaccg ccgataatgc acagccagtt cctaccactt tggtcattag cggatcgcca
     7381 ccgtgaatgc caacgatacg atgtccatcg gtaacataat ccacctcgcc agtgaccacg
     7441 acgattgcgc cagtttcccg tgccagtgtt tgtgcagcag gtatcgcgtt agctgcggca
     7501 tcagtggtat ccactccccg tccgccatta gcaacgccag ctaatgccat gatttccgaa
     7561 gcattaccac gtatggcggt tggcttatga gacagaagtt ccagacaaaa acggcggcga
     7621 taatcgagtg cacccaccgc tactggatca agcgtccagg gtgtttgaga gcgttttgcc
     7681 tgttcaacgg cggcacgcat cgcctgtgcg cgtggctgcg tcagcgtgcc aacgttaatc
     7741 agcaacgcac tggcgattgc cgcaaactga ctggcctctt cggtttcgat gaccatcgct
     7801 ggcgatgcac cgagcgccag taaggtattg gcagtaaagg tttgcaccac atcattggtc
     7861 atacagtgca caagggggga atgtttgtga aaaagatgta acgcgtgcgc agattgcgcg
     7921 gaactcagca ggtcgacttg catagtttgc tcctgccata acgtgaagaa gcaatgacct
     7981 ggtggtccgt gacttcccta cgctggcatt atccagatca ggtgatacgg gtatttctca
     8041 gccttcacgc agaagggcac cccgagtcgt ttggttgcga taataaatcg cagaggagga
     8101 tggtaatgtc cagcgcacgc gttgtaaacg gggaaaaacg gcggtattac aataacgttg
     8161 tgaaattatt tgatataaga atccagcacc ttcagaacga catccagatc ttcttcacgt
     8221 tttagctcat ccccctggtg aacgatgtgt tccgtcagat ggcctttaat cacttcccgc
     8281 atcagaccgt ttaccgcgcc acggatagca gcaatctgtt gtaaaactgc agcgcattcg
     8341 tgcggctcgt cgagcatttt cttgagcgcc acgacctggc cctgaatctt actggcacgc
     8401 gctttcagtt tctgtttatc acggatggta tgagacatgg caacacctgg ttaacaagaa
     8461 tatgaaaaat catagcacta ttaatctact ggggggtagt atcaggtact gggggggagt
     8521 agaatcagat tgccgaatta atactaagaa ttattatcat gaccgaattt accactcttc
     8581 ttcagcaagg aaatgcctgg ttcttcatcc ccagcgccat cttacttggt gcgcttcatg
     8641 gcctggaacc agggcactca aaaacgatga tggcggcgtt tatcatcgcc atcaaaggca
     8701 ccattaaaca ggcggtgatg ctcggactgg cagcaaccat ttcgcatacc gcggtggtct
     8761 ggttgattgc ctttggcggg atggtaatca gcaaacgttt tactgctcaa tctgcagaac
     8821 cgtggctcca gttgatttcc gcggtgatca ttattggcac cgcgttctgg atgttctggc
     8881 gtacctggcg cggcgaacgc aactggctgg agaatatgca cgagcacgag cacgagcacg
     8941 agcatgatca tgagcatcat caccatcacg aacatggcga gtatcaggat gcccatgcac
     9001 gagcccattc caatgacatt aaaagacgat ttgatggtag agaggtcacc aactggcaaa
     9061 ttttgttatt tggcttaacc ggtggcctta tcccctgccc ggcagcaatt accgtgctgt
     9121 tgatttgcat tcagttgaaa gccctgacac tgggcgcaac actggtcgtc agttttagca
     9181 ttggcctggc gttaacgctt gtcaccgtag gcgttggcgc agcaatcagc gttcagcagg
     9241 tcgcaaaacg ctggagcgga tttaacactc tcgctaaacg cgccccctat ttttccagtc
     9301 tgttgattgg cttagttggt gtgtatatgg gcgtacatgg cttcatgggc ataatgcgat
     9361 aactcaatcc tttaggcttg catgttatct tcagcccagg atgattctta aatcagctat
     9421 ttccgctgac tctctgctcg ctaaggatgc ttttagagca tcctttcatt tacacttttt
     9481 acgaaatcat gggatcacta acaaaatatc gcttgtcagt tatattgtat ggcaggaaag
     9541 atatgcgact gatattacag atccccaaag tggagagttt atgaccatta aaaataagat
     9601 gttgctgggt gcgcttttgc tggttaccag tgccgcctgg gccgcaccag ccaccgcggg
     9661 ttcgaccaat acctcgggaa tttctaagta tgagttaagc agtttcattg ctgactttaa
     9721 gcatttcaaa ccaggcgata ccgtcccaga gatgtaccgc accgatgagt acaacattaa
     9781 gcagtggcag ttacgtaacc tgcccgcgcc tgatgccggg acgcactgga cctatatggg
     9841 tggcgcgtac gtgttgatca gcgacaccga cggtaaaatc attaaagcct acgacggtga
     9901 gattttttat catcgctaaa aaaaagcccc ctcgaagaga ggggggaatg cagacacctt
     9961 aatattttta ttattagcca cttgctcgtc ttgcttgtta ttagtcgtat ttcacgttga
    10021 ttaatgcggt tgcctccagt gcgccagatt taactttgtt tgtatcgtag acgtagtaac
    10081 tggccataac tggtatatta ataatattac tatttaaaga agcccctggt ttatctgttt
    10141 tccataatga tgtcgccgcg ccctgattgc cgctagcaga aattttgatg gcagcttcag
    10201 ttccttttga tggttctttt agatccaaca caaatcctac accattatct atgttgccac
    10261 gcaaaattgt attacttcct gtaactaagt cactgctgga aagatatacg accatattcc
    10321 tcgatgcttg gtttttgtcg ccgaaaagat tatcacattt caacgaaatt attccttcct
    10381 tactgttcgc cgtaatcttt ccctgacttc tgagctgggg caaggcaata tcatctactt
    10441 ttattattgt gttttgaggc ttacaggtcg tatttttagg ataataggaa atacttaacc
    10501 caagcgtaaa tgtatccccc gccagtttac tggtgagata atttacacac cagttaatct
    10561 tcaatgcctt acaaactccc aaccaaaagt cgatggatgt agatgactca ccgccaatat
    10621 ttgcaatcac agtatcagaa agaaaccagg ttggttttct ttctccagaa aaatcaagtg
    10681 tacctctggc aattttaacc acatagggta attctgcctg cgcattgctg gatttcccaa
    10741 tcgtttcact gtttttacct aaagactcta ttttaacctt taacttttcg ccattaccaa
    10801 aaggtccaac ttcaacccaa tcactttgga tatttttata aactatttta tccgtgctcg
    10861 tatcacaaga tatcccagta aacacgacat ttttactaaa ggaaacctca ttcgctaaaa
    10921 tctcccccac attaatacta tcagtaatat ttaatgatgc agtggtacga catccagccc
    10981 aggtaaaatt aacccataaa ataaatatta gtaacattcc atttctgaac atcatattcc
    11041 acctctcacc gacagatata atttctactt tcatcaatct ctttaccgaa ggtgattgtg
    11101 catgaaagtc cttgttgctt atcaattgct acattaaccg atggcggtac ttcattggtg
    11161 cgaataaata actggcttcc ctggccgaca acaccaatat tatgaccatg gatatcattg
    11221 acttcataac caaacgttaa tggttgccca tccgctctta acgcttttat aaaccatggc
    11281 ttgcgctgat cggtatcaaa attaaccagt acaaccgcgc cgcgataagg ggcggcaatt
    11341 ttccggttgc cacgtaattc tgcttcgcta tcgctttgcg acacatccag catcaggtga
    11401 ttttcccgat aaggtgtcat tccgtcgtat accaccactc cattacggtt tgttgtgcga
    11461 tatttttgcc cattgacata agcatcttta attcctggcg cattcattac agcaaacgtt
    11521 tcggaaagac ggttcgccag attaacgcca cccgaccagg cgacaatgcc ccctgaaaca
    11581 ctggctccag cctgtcgata agtactcgac tgactataac tgccattcac cgttgccacc
    11641 ggcgcgttcc aggttaaatt agctccagct gtcgtttcat ttccctgatg ctgatgactc
    11701 aggttgaccc catagttaaa ttgatcccgg cttccaacgg ttcccgataa tcccgtatta
    11761 tttgaggcaa aaccctgatc atcaaacgtc gttgagttag acatatatat ttgccgacga
    11821 ggcgtcgtag cgtcatcacc ccaatcaaag ggaatcgata taaaaatatt aaaacgtttc
    11881 tcttcatgat gattctcgtc ataagcctgg cttgccgcga gggtatagct tatccgtcgc
    11941 aggttgttgg aataactcaa ctgataatcc ttactgctgc cgctacgccc ccagtaatct
    12001 cgccataacg tacttaagga cacagaaccc cagccttctg gcaatgactg gctcatattg
    12061 gcagaaaagc tatttttacg gccaaaatcg ttctggtaat aatcggcaat gtcatagata
    12121 tcgttttcat cacggcgata tttatcttta ttgtttgccc aaacgtgatc gttaaatgtc
    12181 cggtaatcac gcgacgaata acgccaggcc gccagaccaa aacgcgtcga cgtttggctc
    12241 acaaatttgt tgtaggcaat ttgataactt tgcccgtcaa acacatcgcc gttgtcttgt
    12301 ttactatgcg acttcgtggc atcgacggaa atggcaccaa tgcgtgtatt ccagccagtc
    12361 cccaaagtga acgcgtaata attattcgcg accatcgatc cgccatacag cgtcaataag
    12421 ttattaaaac catactgata acccgcctga acaaaatcac tttgtttgct cgccccttca
    12481 atatggctac gacctgccgc aaaatcatat ttcgacacgc cgggttgcag catattcggc
    12541 accgctgcat aaggcaccag ataggtggtt accgaaccgt ccgcctcttt cacgctgaca
    12601 tcaagatctg ctccaccacc ggccaactgc aaatctgtaa tcgcaaacgg gccaggagga
    12661 acctctttct gataaaccac aaaaccgttc tgttcaatag ttaccagcgc gttactctga
    12721 gcaatcccct gcacccgtgg agtaaaattt tgtttcgagt taggcaacat ctgcatatca
    12781 cgaaacaacc gcacaccgct gaagcgaaca gaatcaaaaa tatcgcttga tgtgtacata
    12841 tcacccacgc gaagcgtgcc gagaagttgg gcaaatccac gttccagata cagggtattg
    12901 cttttccaca cccctggatt gctatttgtt ttactgaaac tggcatcaga atgcagttgc
    12961 caccccagta agtttaaccc gctgttaaaa cgtacatatg tactcttgct attacccgac
    13021 gctttatagt cgctgtaata ctgactcaca taataagagg tataaaacgc attaataccc
    13081 cgctcccagt tttccggtgg aacatagcca ctttccagtt cttccaccca cgcctgcggg
    13141 acactgaaat cgagacgaaa aactccgata tcccaggtat agctcccccc ctgaacaagt
    13201 tgctcaaatg ttaaacattg cttaccgctg gcaaagttat cggtattaat gcctaaccgc
    13261 ttgataattt cccttgatat acatgtttct tgcaggttgt ctttaacaat aatctcatat
    13321 ttcccgcgcc attgcttatt gacataaata tcgatgtcat actgccccgg caagggttga
    13381 ttatcatcaa gacgaatatt tgcaacctgc tggtctttca ttccacctat cataaaatgg
    13441 gtatcaaagg tttcttcagc tgcataagct tcaatgccga gcaataacgc tacgattgct
    13501 gatgcaagtg gggtcattct caacataggc agctcctgca attaaatttt gtcactaata
    13561 tagttgccat ggtcatcgat aatggtcaga tgccagttat tcgcattatt acttttgaca
    13621 ttaatactct gactttctaa gggggcaatc ataatagttt cataattgac tttgacatta
    13681 ttagctttga catccgaaat cgtcacccaa tttgctgagt cattttttat caccaatcca
    13741 ttgccactgc gatttaccag taacttttta aatgtcgctt tatttaccgg tgcaataccc
    13801 gcaggccggt aaaacaattt gattctgttt tgcattgcaa atttcagtgc attcttgccc
    13861 tcttgctctg gactatttgg tggaatatcc agaacattca gataaaaaat gctctcttta
    13921 ttagtgggca gtttattcgg cataattttg atttttactt gctgcccgga atttgcccct
    13981 atttttgcca ctggtggcgt taacatgaaa ggaacctgaa ttttttctgg tggtaacgac
    14041 gtatcgccat catcaatcca cgcctgcagc agcgaagaac ggtttccctg gttcatcaac
    14101 tgcaccatca cttctttatt ttctgccggg taaataatgc gcgtcccata gataacaatt
    14161 ccggcatgcg caggaaggac catagaagaa atgagtaaag ctaataatcc tttcatctta
    14221 atgcctctta aattaaaagg ccgccatggg gatagcggcc atgtttatta cctggagaaa
    14281 cttgaaattt tatttattaa tcctgcgcca cacgcataac cagagaagat aacacatcac
    14341 ctgattgcac tgaattatct gtcagcttca ggtattttgc tttaaacgga atagcatatt
    14401 gaccttccgc tgttttataa ctctcaatgt taaaaggtgc agaaacatcc aggacatcgc
    14461 tgttatcacc taaatagaga tagtacccca cggtatcgtt gctactggct atcgccttat
    14521 cgtttccggt tattttctcg ttggtaatca acgagagttt tacaccagca acttctttcg
    14581 gacagctaat ttttaacatg ctgctggtta caccgactgc atcatcatag gtcgagtatt
    14641 tagctttacc ttcaaagaca gtggttggta cagttggcat attaatactt actgaatcgc
    14701 cacccgcttc gaatttacac ggagattctg caatattccc tttaatggtt aatgttccgg
    14761 tatcaacgtc tgcggcaaat accccagcgc tcataaaaaa agaagaaaag acagcggcag
    14821 caa
//
LOCUS       DADXDL010000107        14742 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.107, whole genome shotgun sequence.
ACCESSION   DADXDL010000107 DADXDL010000000
VERSION     DADXDL010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14742
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.107"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1014)
                     /locus_tag="IRB70_004059"
     CDS             complement(<1..1014)
                     /locus_tag="IRB70_004059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000147908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBC0633911.1"
                     /translation="MTGSEMAKAGLLEQNRLSGANRNTLIAGGIMANTAEIFNFPVPD
                     AAQKEPRVADLDDGYTRIANELLEAVMLAGLTQHQLLVFLAVMRKTYGFNKKLDWVSN
                     EQLSGLTGILPHKCSAAKSVLVKRGILIQSGRNIGINNVVSEWSTLPESGKKNKVYLK
                     EVNLPESGKKSLPKSGKGVYPNQVNTKDKLTKDNIKPFSSENSGESSDQPENDLPVVK
                     PDAAIQSGSKWGTAEDLTAAEWMFDMVKTIAPSARKPNFAGWANDIRLMRERDGRNHR
                     DMCVLFRWACQDNFWSGNVLSPAKLRDKWTQLEINRNKQQAGMIASKPKLDLTNTDWI
                     YGVD"
     gene            complement(1011..1550)
                     /locus_tag="IRB70_004060"
     CDS             complement(1011..1550)
                     /locus_tag="IRB70_004060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001182892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin YdaT domain-containing protein"
                     /protein_id="HBC0633912.1"
                     /translation="MQPLPYQQTSGFSPTAVINRSQTKQVPGHEKIRDAVRAWSAVDN
                     QDVVATLIVNEYREQGGGTIDFPDDVSRARQKLFRFLDNKFDSEKYRNNVRELTPAIL
                     AVLPLEYRGYLVEQDSFMARLAEMEKELSEAKQAVILNAPRHQKLKEISEGIVSMFRV
                     DPDLAGPLMAMVTTMLGAI"
     gene            complement(1620..1850)
                     /locus_tag="IRB70_004061"
     CDS             complement(1620..1850)
                     /locus_tag="IRB70_004061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001067458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0633913.1"
                     /translation="MNPAIKTAINIVGSQKKLGAACEVSQQAVYKWLHNKAKVSPEHV
                     GSIVTATGGVVKAYQIRPDLPKLFPHTEKNAA"
     gene            1955..2644
                     /locus_tag="IRB70_004062"
     CDS             1955..2644
                     /locus_tag="IRB70_004062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000858971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0633914.1"
                     /translation="MKTTLSERLKEARLARGLTQKALGDLVGVSQAAIQKIETGKANQ
                     TTKIVEIANALGVRAEWLSSGVGNMSDSTVQPIQSTVSHSKYFKIDVLDIEVSAGPGV
                     INREFVEVLRSVEYSFDDARHMFDGRKAENIRIINVRGDSMSGTIEPGDLLFVDITVK
                     SFDGDGIYAFLYDDTAHVKRLQMMKDKLLVISDNKSYSPWDPIEKDEMNRVFIFGKVI
                     GSMPQTYRKHG"
     gene            3239..3445
                     /locus_tag="IRB70_004063"
     CDS             3239..3445
                     /locus_tag="IRB70_004063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001524508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division inhibitor protein"
                     /protein_id="HBC0633915.1"
                     /translation="MVHQHYGTQTVNRGAVMPGMLVKHKDGTWTASANLRGRLYLHRG
                     IERTYTSDLLVEVFLDGRGNGLNH"
     gene            3522..3818
                     /locus_tag="IRB70_004064"
     CDS             3522..3818
                     /locus_tag="IRB70_004064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309203.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="host-nuclease inhibitor protein Gam"
                     /protein_id="HBC0633916.1"
                     /translation="MNAYYIQDRLEAQSWARHYQQLAREEKEAELADDMEKGLPQHLF
                     ESLCIDHLQRHGASKKAITRAFDDDVEFQERMAEHIRYMVETIAHHQVDIDSEV"
     gene            3824..4609
                     /gene="bet"
                     /locus_tag="IRB70_004065"
     CDS             3824..4609
                     /gene="bet"
                     /locus_tag="IRB70_004065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage recombination protein Bet"
                     /protein_id="HBC0633917.1"
                     /translation="MSTALATLAGKLAERVGMDSVDPQELITTLRQTAFKGDASDAQF
                     IALLIVANQYGLNPWTKEIYAFPDKQNGIVPVVGVDGWPRIINENQQFDGMDFEQDNE
                     SCTCRIYRKDRNHPICVTEWMDECRREPFKTREGREITGPWQSHPKRMLRHKAMIQCA
                     RLAFGFAGIYDKDEAERIVENTAYTAERQPERDITPVNDETMQEINTLLIALDKTWND
                     DLLPLCSQIFRRDIRASSELTQAEAVKALGFLKQKATEQKVAA"
     gene            4606..5286
                     /locus_tag="IRB70_004066"
     CDS             4606..5286
                     /locus_tag="IRB70_004066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBC0633918.1"
                     /translation="MTPDIILQRTGIDVRAVEQGDDAWHKLRLGVITASEVHNVIAKP
                     RSGKKWPDMKMSYFHTLLAEVCTGVAPEVNAKALAWGKQYENDARTLFEFTSGVNVTE
                     SPIIYRDESMRTACSPDGLCSDGNGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQY
                     SMWVTRKDAWYFANYDPRMKREGLHYVVVERDEKYMASFDEMVPEFIEKMDEALAEIG
                     FVFGEQWR"
     gene            5283..5465
                     /locus_tag="IRB70_004067"
     CDS             5283..5465
                     /locus_tag="IRB70_004067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1317 domain-containing protein"
                     /protein_id="HBC0633919.1"
                     /translation="MTHPHDNIRVGAITFVYSVTKRGWVFPGLSVIRNPLKAQRLAEK
                     INNKREAVCTKHLLLS"
     gene            5438..5629
                     /locus_tag="IRB70_004068"
     CDS             5438..5629
                     /locus_tag="IRB70_004068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1382 family protein"
                     /protein_id="HBC0633920.1"
                     /translation="MHKASPVELRTSIEMAHSLAQIGVRFVPIPVETDEEFHTLATSL
                     SQKLEMMVAKAEADERDQV"
     gene            5640..5922
                     /locus_tag="IRB70_004069"
                     /pseudo
     CDS             5640..5922
                     /locus_tag="IRB70_004069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016239470.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            6021..6239
                     /locus_tag="IRB70_004070"
     CDS             6021..6239
                     /locus_tag="IRB70_004070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TraR/DksA family transcriptional regulator"
                     /protein_id="HBC0633921.1"
                     /translation="MADIIDSASEIEELQRNTAIKMRRQNYQTVSATHCCECGDPIAE
                     RRRLAVQGCRTCASCQEEIELKNKQWGL"
     gene            6287..6565
                     /locus_tag="IRB70_004071"
     CDS             6287..6565
                     /locus_tag="IRB70_004071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000490216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4222 domain-containing protein"
                     /protein_id="HBC0633922.1"
                     /translation="MFRIIFPNTWYVDHHGTPCKILRSTHNKVHYIRKGRTCIASMFR
                     FNHDFEPVNKADADRIAEEIETAEHIKKLRDMRSKSRGNHGIIQPHTR"
     gene            6764..7927
                     /locus_tag="IRB70_004072"
     CDS             6764..7927
                     /locus_tag="IRB70_004072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBC0633923.1"
                     /translation="MSLFRRNEIWYASYSLPGGKRIKESLGTKDKRQAQELHDKRKAE
                     LWRVEKLGDLPDVTFEEACLRWLEEKADKKSLDSDKSRIEFWLEHFEGIRLKDISEAK
                     IYSAVSRMHNRKTKEIWKQKVQAAIRKGKELPVYEPKPVSTQTKAKHLAMIKAILRAA
                     ERDWKWLEKAPVIKIPAVRNKRVRWLEKEEAKRLIDECPEPLKSVVKFALATGLRKSN
                     IINLEWQQIDMQRRVAWVNPEESKSNRAIGVALNDTACKVLRDQIGKHHKWVFVHTKA
                     AKRADGTSTPAVRKMRIDSKTSWLSACRRAGIEDFRFHDLRHTWASWLIQSGVPLSVL
                     QEMGGWESIEMVRRYAHLAPNHLTEHARKIDDIFGDNVPNMSHSGIMEDIKKA"
     gene            complement(7943..8019)
                     /locus_tag="IRB70_004073"
     tRNA            complement(7943..8019)
                     /locus_tag="IRB70_004073"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7983..7985),aa:Arg,seq:tct)
     gene            8261..8893
                     /gene="fimZ"
                     /locus_tag="IRB70_004074"
     CDS             8261..8893
                     /gene="fimZ"
                     /locus_tag="IRB70_004074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria biosynthesis transcriptional regulator
                     FimZ"
                     /protein_id="HBC0633924.1"
                     /translation="MKPTSVIIMDTHPIIRMSIEVLLQKNSELQIVLKTDDYRITIDY
                     LRTRPVDLIIMDIDLPGTDGFTFLKRIKQIQSTVKVLFLSSKSECFYAGRAIQAGANG
                     FVSKCNDQNDIFHAVQMILSGYTFFPSETLNYIKSNKCSTNSSTVTVLSNREVTILRY
                     LVSGLSNKEIADKLLLSNKTVSAHKSNIYGKLGLHSIVELIDYAKLYELI"
     gene            complement(8896..9411)
                     /gene="sfmF"
                     /locus_tag="IRB70_004075"
     CDS             complement(8896..9411)
                     /gene="sfmF"
                     /locus_tag="IRB70_004075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria assembly protein"
                     /protein_id="HBC0633925.1"
                     /translation="MRRVLFSCFCGLLWSSSGWAVDPLGTININLHGNVVDFSCTVNT
                     ADKDKTVDLGRWPTTQLLSAGDTTALVPFSLRLEGCPPGSVAILFTGTPASDANLLAL
                     DDPAMAQTVAIELRNSDRSRLALGEASSTEEVDANGNVTLNFFANYRALASGVQPGVA
                     KADAIFMINYN"
     gene            complement(9422..10429)
                     /gene="fimH"
                     /locus_tag="IRB70_004076"
     CDS             complement(9422..10429)
                     /gene="fimH"
                     /locus_tag="IRB70_004076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308622.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrin D-mannose specific adhesin FimH"
                     /protein_id="HBC0633926.1"
                     /translation="MKIICRLLLAMACLWLTNISWATVCANSTGVAEDEHYDLSNVFN
                     STNNQPGQIVVLPEKSGWVGVSAICPPGTLVNYTYRSYVTNFIVQETIDNYKYMQLND
                     YLLGAMSLVDSVMDIQFPPQNYIRMGTDPNVSQNLPFGVMDSRLIFRLKVIRPFINMV
                     EIPRQVMFTVYVTSTPNDPLVTPVYTISFGGRVEVPQNCELNAGQIVEFDFGDIGASL
                     FSAAGPGNRPAGVMPQTKSIAIKCTNVAAQAYLTMRLEASAVSGQAMVSDNQDLGFIV
                     ADQNDTPITPNDLNSVIPFRLDAAAAANVTLRAWPISITGQKPTEGPFSALGYLRVDY
                     Q"
     gene            complement(10442..13051)
                     /locus_tag="IRB70_004077"
     CDS             complement(10442..13051)
                     /locus_tag="IRB70_004077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis usher protein"
                     /protein_id="HBC0633927.1"
                     /translation="MKIPTTTDIPQRYTWCLAGICYSSLAILPSFLSYAESYFNPAFL
                     LENGTSVADLSHFERGNHQPAGVYRVDLWRNDEFIGSQDIVFESTTVNTGDKSGGLMP
                     CFNQALLERIGLNSSAFPELAQQQNNKCINLLKAVPDATINFDFAAMRLNITIPQIAL
                     LSSAHGYIPPEEWDEGIPALLLNYNFTGNRGNGNDSYFFSELSGINIGPWRLRNNGSW
                     NYFRGNGYHSEQWNNIGTWVQRAIIPLKSELVMGDGNTGSDIFDGVGFRGVRLYSSDN
                     MYPDSQQGFAPTVRGIARTAAQLTIRQNGFIIYQSYVSPGAFEITDLHPTSSNGDLDV
                     TIDERDGNQQNYTIPYSTVPILQREGRFKFDLTAGDFRSGNSQQSSPFFFQGTALGGL
                     PQEFTAYGGTQLSANYTAFLLGLGRNLGNWGAVSLDVTHARSQLADDSRHEGDSIRFL
                     YAKSMNTFGTNFQLMGYRYSTQGFYTLDDVAYRRMEGYEYDYDYDGEHRDEPIIVNYH
                     NLRFSRKDRLQLNISQSLNDFGSLYISGTHQKYWNTSDSDTWYQVGYTSSWVGISYSL
                     SFSWNESVGIPDNERIVGLNVSVPFNVLTKRRYTRENALDRAYASFNANRNSNGQNSW
                     LAGVGGTLLEGHNLSYHVSQGDTSNNGYTGSATANWQAAYGTLGVGYNYDRDQHDVNW
                     QLSGGVVGHENGITLSQPLGDTNVLIKAPGAGGVRIENQTGILTDWRGYAVMPYATVY
                     RYNRIALDTNTMGNSIDVEKNISSVVPTQGALVRANFDTRIGVRALITVTQGGKPVPF
                     GSLVRENSTGITSMVGDDGQVYLSGAPLSGELLVQWGDGANSRCIAHYVLPKQSLQQA
                     VTVISAVCTHPGS"
     gene            complement(13082..13774)
                     /gene="fimC"
                     /locus_tag="IRB70_004078"
     CDS             complement(13082..13774)
                     /gene="fimC"
                     /locus_tag="IRB70_004078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbria chaperone FimC"
                     /protein_id="HBC0633928.1"
                     /translation="MMTKIKLLMLIIFYLIISVSAHAAGGIALGATRIIYPADAKQTA
                     VWIRNSHTNERFLVNSWIENSSGVKEKSFIITPPLFVSEPKSENTLRIIYTGPPLAAD
                     RESLFWMNVKTIPSVDKNALNGRNVLQLAILSRMKLFLRPIQLQELPAEAPDTLKFSR
                     SGNYINVHNPSPFYVTLVNLQVGSQKLGNAMAAPRVNSQIPLPSGVQGKLKFQTVNDY
                     GSVTPVREVNLN"
     gene            complement(13994..14536)
                     /gene="fimA"
                     /locus_tag="IRB70_004079"
     CDS             complement(13994..14536)
                     /gene="fimA"
                     /locus_tag="IRB70_004079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308619.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial major subunit FimA"
                     /protein_id="HBC0633929.1"
                     /translation="MKLRFISSALAAALFAATGSYAAVVDGGTIHFEGELVNAACSVN
                     TDSADQVVTLGQYRTDIFNAVGNTSALIPFTIQLNDCDPVVAANAAVAFSGQADAIND
                     NLLAIASSTNTTTATGVGIEILDNTSAILKPDGNSFSTNQNLIPGTNVLHFSARYKGT
                     GTSASAGQANADATFIMRYE"
BASE COUNT         4116 a         3480 c         3375 g         3771 t
ORIGIN      
        1 atccaccccg taaatccagt cagtgtttgt caggtcgagt tttggtttgc tggctatcat
       61 gcctgcctgt tgcttgttac ggttgatttc gagttgggtc cacttgtcgc ggagtttggc
      121 cggacttagc acgttaccgg accagaagtt gtcctggcat gcccagcgga aaagcacgca
      181 catgtcgcgg tggttacgtc cgtcacgttc acgcatcagg cggatatcgt tagcccaccc
      241 tgcaaaattc ggttttctgg ctgatggtgc gatggtcttc accatgtcaa acatccactc
      301 tgcggcggtc aggtcttctg ctgtccccca cttgctgccg ctctgaattg cagcatctgg
      361 tttcaccaca ggaagatcgt tttctggttg gtcagaggat tcgccagaat tctcggacga
      421 aaaaggtttt atattgtctt ttgttagttt gtcttttgtg tttacctgat tcgggtaaac
      481 gcctttacct gatttgggta aacttttctt acctgattca ggtaaattta cctctttcag
      541 gtaaacttta tttttcttac ctgattcggg taatgttgac cattcactga ccacattatt
      601 aataccgata ttccgcccgc tctgaatcaa aatcccacgc tttaccagaa cactttttgc
      661 agcagaacac ttgtgcggta atatcccggt caatccggac agttgctcgt tgctcaccca
      721 atccagtttt ttattaaagc catatgtttt gcgcatgaca gccaggaaga ccagaagctg
      781 gtgctgtgtt aatccggcca gcatcacagc ttccagcaac tcatttgcaa tgcgcgtata
      841 accatcatcg agatctgcca cgcgcggctc cttttgtgcc gcatccggca ctggaaaatt
      901 gaatatctca gcagtgtttg ccataattcc tcccgcaatg agtgtgttac gatttgcacc
      961 tgaaagtcgg ttctgttcca gcagaccggc tttcgccatt tctgaacctg tcatatcgcc
     1021 cccagcatgg tagtaaccat cgccatcaat ggaccagcca gatctgggtc cacacgaaac
     1081 atcgatacaa taccttcact aatttccttc agtttctggt ggcgtggtgc gttgagaatg
     1141 acagcctgtt ttgcctcact gagttccttt tccatttcag ccaacctggc catgaagcta
     1201 tcctgctcaa ccaggtaacc gcgatattcc agcggtagta ccgccagaat tgccggggtc
     1261 agttcacgca cgttatttcg gtatttttca gaatcgaatt tgttatcgag gaagcggaac
     1321 agcttctggc gtgcacggct gacatcatca gggaaatcga tggtgccgcc gccctgctcc
     1381 cgatactcat tcacaatgag tgtggcaacg acatcctgat tatctacagc cgaccaggcg
     1441 cggacggcat cacggatttt ttcgtggcct ggcacctgtt ttgtttgaga acgatttatc
     1501 accgcagtcg ggctaaatcc gctagtctgt tggtatggaa gtggttgcat aattgactcc
     1561 tttagtttga attgactgtt aagttgattg cttattgtta aagagcgtga aatggaaatt
     1621 taagctgcgt tcttttcggt gtgtggaaac aacttcggaa gatccgggcg aatctggtat
     1681 gccttcacta ctccaccagt agccgtaaca atgctgccga catgttcagg ggataccttt
     1741 gctttgttgt gaagccactt atagacggcc tgctgtgaaa cttcgcaagc agcgcccagt
     1801 ttcttttgtg aaccaacgat attgatcgct gttttgatag ctgggttcat aacaacctcc
     1861 gtggttaatt tgaatcaaga ttaaaactat ggttgttttt agtcaacaac cattttcgtt
     1921 tgatggaata aaaccttggt tgtacatttg gactatgaaa acaacactct cagaaagact
     1981 taaagaagcc agattagcgc gaggccttac acaaaaggcg cttggggatt tggtcggggt
     2041 tagccaggct gctattcaga aaatcgaaac agggaaagct aatcaaacaa ctaaaatcgt
     2101 ggagatcgcg aacgctttgg gtgtgcgcgc agaatggtta tcttctggcg ttggaaatat
     2161 gtcagacagt acagtgcaac caatacaatc aactgtcagc cattccaaat acttcaagat
     2221 tgacgttctt gatatagaag tcagtgctgg gccgggagtc atcaaccgtg agtttgtaga
     2281 agttctacgc tcggttgagt actcgtttga cgatgctcgt cacatgttcg atggtaggaa
     2341 ggcggaaaat atccgcatca ttaacgtgcg tggtgacagc atgtcaggaa cgatcgaacc
     2401 aggtgatctg ctgttcgttg atatcacagt taaatctttc gacggtgatg gtatctatgc
     2461 gtttctgtac gacgacacag cccatgtaaa gcgcctgcaa atgatgaagg ataagctgct
     2521 ggtcatctct gataacaaaa gctactcacc gtgggacccg atcgagaaag acgagatgaa
     2581 ccgggtgttc atcttcggta aggttattgg gagcatgccg cagacatata ggaagcatgg
     2641 gtagtaccaa ttaaaaatta tcaactgggc attgtgctca ttcagtaaag aactaattcc
     2701 tatctttgct ctaggtagta atattaagcc accgcaataa tatctttacc taacggcgta
     2761 agaatcccgg tcaccgtgcc gggttttctt ttgccctccc ctcatcacac acaccgttaa
     2821 aaaaaccacc ataacctcgc ttcagttatc gctatgcgat tcaagtcaca aaataaatcc
     2881 atcctaaata caaccagtta tatctaaaac aaccaataaa acaacttttg ttgttgacga
     2941 taaaacaact atagttttaa ataagttcat cgcaacaaca caacgatacg gcaactacct
     3001 gattcaccgt tgcgatgacc gcttagatcc gcagtttgaa tttcagcagg cttcggggag
     3061 tgcgaggggt gaaacggacg cgtgaacgtc ggtgtgacca gctgaaatta actcaacatt
     3121 tcatacctca gtcgcttcaa cgaggcggct tagttatgac aaccggcggc catccaccgc
     3181 ctgaatatgc gcagaagtct ctatatgttc agcagcccag cttacgggcg gagtttttat
     3241 ggttcatcaa cattacggaa cacagaccgt taatcgcggc gcggtcatgc caggaatgct
     3301 ggtcaaacac aaagatggta cctggactgc atcagctaat ttacgcggac ggctttatct
     3361 gcatcgcggc atcgagcgca cttataccag tgatttgctc gtggaagttt ttctcgacgg
     3421 acgcggtaac ggcctgaatc actaaccccc ctttcctgtt ttcctaatca gcctggcatt
     3481 tcgcgggcga tattttcaca gccattttca ggagttcagc catgaacgct tattacattc
     3541 aggatcgtct tgaggctcag agctgggcgc gtcactacca gcagctcgcc cgtgaagaga
     3601 aagaggcaga actggcagac gacatggaaa aaggtctgcc ccagcacctg tttgaatcac
     3661 tctgcatcga tcatttacaa cgccacgggg ccagcaaaaa agccattacc cgtgcgtttg
     3721 atgacgatgt tgagtttcag gagcgcatgg cagaacacat ccggtacatg gttgaaacca
     3781 ttgctcacca ccaggttgat attgattcag aggtataaaa cggatgagta cagcactcgc
     3841 aacgctggct gggaagctgg ctgaacgcgt cggcatggat tctgtcgacc cacaggaact
     3901 gatcaccact cttcgccaga cggcatttaa aggtgatgcc agcgatgcgc agttcatcgc
     3961 attgctgatc gtcgccaacc agtacggcct taatccgtgg acgaaagaaa tttacgcctt
     4021 ccctgacaag cagaacggca tcgttccggt ggtgggcgtt gatggctggc cccgtatcat
     4081 caatgaaaac cagcagtttg atggcatgga ctttgagcag gacaatgaat cctgcacatg
     4141 ccggatttac cgcaaggacc gcaatcatcc gatctgcgtt accgagtgga tggatgaatg
     4201 ccgccgcgaa ccattcaaaa cccgcgaagg cagagaaatc acggggccgt ggcagtcgca
     4261 tcccaaacgg atgttacggc ataaagccat gattcagtgt gcccgtctcg ccttcggatt
     4321 tgctggtatc tatgacaagg atgaagccga gcgcattgtc gaaaataccg catacactgc
     4381 agaacgtcag ccggaacgcg acatcactcc ggttaacgat gaaaccatgc aggagattaa
     4441 cactctgctg atcgccctgg ataaaacatg gaatgacgac ttattgccgc tctgttccca
     4501 gatatttcgc cgcgacattc gcgcatcgtc agaactgaca caggccgaag cagtgaaagc
     4561 tcttggtttc ctgaaacaga aagccactga gcagaaggtg gcagcatgac accggacatt
     4621 atcctgcagc gtaccgggat cgacgtgaga gctgtcgaac agggggatga tgcatggcac
     4681 aaattacggc tcggcgtcat caccgcttca gaagttcaca acgtgatagc caagccccgc
     4741 tcaggaaaga agtggcctga catgaaaatg tcctacttcc acaccctgct ggctgaggtt
     4801 tgcaccggtg tggctccgga agttaatgct aaggcgctgg catggggaaa acagtacgag
     4861 aacgacgcca gaactctgtt tgaattcact tccggcgtga atgttactga atccccgatc
     4921 atctatcgcg acgaaagtat gcgcaccgcc tgctctcccg atggtttatg cagtgacggc
     4981 aatggccttg agctgaaatg cccgtttacc tcccgggatt tcatgaagtt ccggctcggt
     5041 ggtttcgagg ccataaagtc ggcttacatg gcccaggtgc agtacagcat gtgggtgaca
     5101 cgaaaagatg cctggtactt tgccaactat gacccgcgta tgaagcgtga aggactgcat
     5161 tatgtcgtgg ttgagcggga tgaaaagtac atggcgagtt ttgacgagat ggtgccggag
     5221 ttcatcgaaa aaatggacga ggcactggct gaaattggtt ttgtatttgg ggagcaatgg
     5281 cgatgacgca tcctcacgat aatatccggg taggcgcgat cactttcgtc tactccgtta
     5341 caaagcgagg ctgggtattt cccggccttt ctgttatcag aaatccactg aaagcacagc
     5401 ggctggctga gaagataaat aataaacggg aggcggtatg cacaaagcat ctcctgttga
     5461 gttaagaacg agtattgaga tggcacatag ccttgctcaa attggagtca ggtttgtgcc
     5521 aataccagta gaaacagacg aagaatttca tacgttagcc acatcccttt cacaaaagct
     5581 ggaaatgatg gtggcgaaag cagaagcaga tgagagagac caggtatgac aaccactgaa
     5641 tgcatttttc tggcagcggg cttcatattc tgtgtgctta tgcttgccga catggggctt
     5701 gtttaatgac acctcagcaa gaaaacgccc ttcgcagcat tgcccgtcag gctaattctg
     5761 aaatcaaaaa aagccagaca gcagtttccg gataaaaacg tcgatgacat ttgccgtagc
     5821 gtactgaaga agcaccgcga aacggtaacg ctgatgggat tcacaccaac tcatttaagc
     5881 ctggcgatcg gcatgttaaa cggcgtcttt aaggaacgat gaacatgaaa agcaaaatta
     5941 tcagggagct acaggctcct tttttattgt tcgcattcac cctcaagcgt attaaccaac
     6001 agttcaggga ttaatgaaag atggcagaca tcattgattc agcatcagaa atcgaagaat
     6061 tacagcgcaa tacagcaata aaaatgcgtc gtcagaacta ccagactgta tccgcaactc
     6121 attgttgtga gtgtggcgat ccgatagctg agcgaagacg cctggctgtt cagggttgtc
     6181 ggacttgtgc aagttgccag gaggagatcg aacttaagaa caaacaatgg ggactgtgat
     6241 ggcctcaaag cagcaaattt caacatcgtc caactgaggt gtaaaaatgt tcagaatcat
     6301 ttttcctaac acctggtacg tcgaccacca cggcactccc tgcaaaatcc tgcgttctac
     6361 ccacaacaaa gttcactaca tccgaaaagg cagaacatgt atcgccagca tgttccgctt
     6421 taatcatgac tttgaacctg tgaataaagc tgatgcagat cggatagcag aagagatcga
     6481 aacggcagaa cacattaaga agttacgtga catgcgttca aaaagcagag gtaaccatgg
     6541 aatcatacag cctcacactc gatgaggcct gtcagtttct taagatatcc agaccaaccg
     6601 ccaccaactg gatacgaaca ggccgcctac aggcaacacg taaagatcca accaagccaa
     6661 aatctcctta cctcacaaca cggcaagcct gcattgcggc gcttcagtct ccgctgcata
     6721 ctgtccaggt gagcgcgggt gatggcataa cagaggaaag aaaatgtcac tcttccgcag
     6781 aaatgaaata tggtatgcct cgtattcgct cccgggcggg aaacgaatta aggaatctct
     6841 tggcacaaag gacaagcggc aagctcagga gttgcacgac aagcgaaaag cagaactctg
     6901 gcgagtagaa aagctagggg atttacctga tgtcactttt gaagaggcct gcctaagatg
     6961 gcttgaggaa aaagctgata aaaaatctct cgattcagat aaaagccgga ttgagttctg
     7021 gcttgaacat tttgagggta taaggcttaa agatatctcg gaggcaaaga tttactctgc
     7081 tgtaagcaga atgcataaca gaaagacgaa agaaatatgg aaacagaaag ttcaggccgc
     7141 catcaggaaa ggtaaagaac tgcctgttta tgaaccaaag ccagtatcaa ctcagacaaa
     7201 ggcaaagcat cttgccatga taaaggccat tctccgtgct gcagaacgcg actggaagtg
     7261 gctggaaaaa gcgcctgtca tcaagatacc agcggtcaga aacaagcgag tcagatggct
     7321 ggaaaaggag gaagcaaaac gccttattga tgagtgcccc gaaccactga aatctgtcgt
     7381 caagtttgcg ctggcaactg gtctgagaaa gtcgaacatc ataaatctgg aatggcaaca
     7441 aatcgacatg cagcgacgag ttgcctgggt gaatccagaa gagagcaaat caaaccgcgc
     7501 cattggtgtg gcgctgaacg ataccgcctg taaagtgttg cgtgatcaaa taggcaagca
     7561 tcacaaatgg gtgtttgtac ataccaaggc ggctaagcga gcagatggaa catcaacgcc
     7621 tgcggtcagg aagatgcgca tcgacagcaa gacatcatgg ctatcagctt gtcgtcgtgc
     7681 aggaattgaa gatttccgtt tccatgacct cagacacacc tgggcaagct ggctgattca
     7741 gtcaggcgtc ccattatcag tgcttcagga aatgggcgga tgggagtcca tagaaatggt
     7801 tcgtaggtat gctcaccttg cgcctaatca tttgacagag catgcgagga aaatagacga
     7861 catttttggt gataatgtcc caaatatgtc ccactctgga attatggagg atataaagaa
     7921 ggcgtaactg attgaattgt aatggcgcgc cctgcaggat tcgaacctgc ggcccacgac
     7981 ttagaaggtc gttgctctat ccaactgagc taagggcgcg ttgataccgc aatgcggtgt
     8041 aatcgcgtga attatacggt caacccttgc tgagtcaatg gcttttgatc tggttgctga
     8101 acaagtgaac gaccgcgtct gattttctga tttatttcgt tatagcggca aacaaacgca
     8161 caccgctgcg cgtctgaatc aggaaaaccc gtattttcat gtatcaagta caatttaccg
     8221 ccctaacgga aaattgtccg atccaatgag actggtaact atgaaaccaa cgtcggtgat
     8281 cattatggat actcatccta tcatcagaat gtctattgaa gttctgttgc aaaaaaacag
     8341 tgaattgcag attgtcctga aaacggatga ttaccgcata accatcgatt atctccgaac
     8401 ccgtcctgtt gatttaatca ttatggatat agacttgccc ggtacagacg gttttacctt
     8461 cctaaaaagg atcaaacaaa ttcagagtac agtgaaagta ttatttttat catcgaaatc
     8521 agaatgcttt tatgctggca gagcgataca agctggtgct aacggttttg tcagtaaatg
     8581 caatgatcag aatgatattt ttcatgccgt tcagatgatt ctctccggat acactttttt
     8641 tcccagcgaa acgctcaact atataaaaag caataaatgt agtacgaata gttcaacggt
     8701 cactgtgcta tctaatcgtg aagtaaccat attacgttat ctggttagcg gattatctaa
     8761 taaagaaatt gccgataagt tattacttag caataaaaca gttagtgcac ataaatctaa
     8821 tatttatggc aagctaggtt tgcattcaat tgtagagctt atcgactacg ccaaattata
     8881 tgaattaata taatattaat tataattgat cataaatatc gcatccgctt tcgccacacc
     8941 aggctgaaca ccgctggcta acgctcgata attggcaaaa aagtttagtg tgacattgcc
     9001 atttgcatca acttcctcag tcgagctcgc ctcccccagt gcgagccggg agcgatcgct
     9061 attacgtaat tcgatggcga cggtttgtgc cattgcggga tcatccagag ccagcaggtt
     9121 ggcatcagat gccggcgttc ccgtaaataa aatcgcaact gaacccggag gacatccctc
     9181 cagccgcagg ctaaaaggga cgagtgccgt ggtatcgcca gcgctcagta attgtgtcgt
     9241 aggccatctg cctaaatcta ccgtcttatc cttatccgct gtgtttacgg tacaggagaa
     9301 atcaacaacg ttaccgtgca aattgatatt aatcgttcct aaagggtcaa ctgcccatcc
     9361 actggaactc cacagtagcc cgcagaaaca gctaaagagt actcttctca ttctccgtac
     9421 ctcattgata atcgacgcgt aaatacccca gcgcgctaaa cggcccttcg gtcggttttt
     9481 gaccggtaat actgataggc caggcgcgaa gtgtgacatt ggctgccgca gctgcatcca
     9541 gacggaaagg aataacgcta ttgagatcgt taggcgtgat cggcgtatcg ttctgatcgg
     9601 ccacaataaa acctaaatcc tgattgtccg acaccatcgc ctgaccagaa acggcactgg
     9661 cttccagacg cattgttaaa taagcctgcg cagcaacatt cgtacatttg atcgcaatgc
     9721 tcttggtttg cggcatgaca ccagctggtc gattccccgg ccctgccgca ctaaataacg
     9781 atgcgccgat atcaccaaaa tcaaattcaa caatttgccc ggcatttaat tcgcagtttt
     9841 gcggtacttc aacccggcca ccaaaactaa tggtataaac aggtgtaacc aacggatcgt
     9901 taggcgttga tgtcacatac acggtaaaca tcacctgtct ggggatctcc accatgttaa
     9961 taaagggacg aataaccttt aaacgaaata tcaaacgaga atccatcacc ccgaacggaa
    10021 ggttttgcga aacgttagga tctgttccca tacgaatata attttgcgga gggaattgaa
    10081 tatccatcac gctatcaacc agactcatcg cacctaatag ataatcattt aattgcatat
    10141 atttataatt atcgatagtt tcctgaacaa taaagttggt gacataacta cggtatgtat
    10201 aattcaccag cgtgccgggt ggacaaattg ctgatacacc tacccagccg gatttttccg
    10261 gtaaaacaac aatctgccct ggctggttat tggtgctatt aaagacattt gagagatcat
    10321 agtgttcatc ttctgctacg ccagtactat ttgcacaaac agtagcccag gatatgtttg
    10381 ttaaccacaa acatgccatc gccaataata atctgcagat tatcttcatt gataatttcc
    10441 tttatgagcc aggatgtgtg caaactgccg aaataacagt gacggcttgc tgtaagcttt
    10501 gcttcggcaa tacatagtgc gctatgcagc gtgagttcgc gccgtctccc cactgaacca
    10561 gtaattcacc agacaatggc gcaccgctta aataaacttg cccgtcatca cccaccatac
    10621 tggttattcc ggtactgttt tcccgtacca gtgatccaaa cggcaccggt tttccgccct
    10681 gggtaacggt aatgagcgcc cgcacgccta tgcgggtatc aaaattggca cgaaccaacg
    10741 cgccttgcgt cggcacaacg ctgctaatat ttttttcaac atcgatggaa ttccccatcg
    10801 tattggtatc aagcgcgata cggttatacc gataaaccgt ggcatacggc atcaccgcat
    10861 agccgcgcca gtcggttaaa attccagttt gattttcaat gcgtacaccg cctgcgcctg
    10921 gcgctttaat caaaacattg gtatccccta aaggctggct cagcgttata ccattttcat
    10981 gcccgaccac accgccagac agctgccagt taacgtcatg ttgatcgcgg tcgtagttat
    11041 acccgacccc cagcgtaccg taagcggcct gccagtttgc cgtggcgctg cccgtatacc
    11101 cattattcga ggtatcgccc tggcttacgt gataactcag gttgtggcct tccagtaagg
    11161 tcccaccaac gcctgccagc cagctatttt gcccgttgct gttacggttg gcgttaaagg
    11221 aggcataagc gcggtcgagc gcattttccc gggtgtagcg acgtttggtc agaacattga
    11281 aaggcactga aacattaagt ccgacaatac gttcgttatc ggggatccct acagattcat
    11341 tccacgaaaa tgagagtgaa taactgatgc caacccagct gctggtatac cccacctgat
    11401 accaggtatc tgaatccgaa gtattccagt atttttgatg ggtaccagaa atataaagcg
    11461 agccaaagtc attaagtgat tgtgaaatat ttaactgcaa acggtcttta cgactaaagc
    11521 gtaaattgtg gtaattcacg attatcggtt catcgcgatg ctcaccgtca taatcgtaat
    11581 catattcgta cccctccatt cgacgatacg caacatcatc aagagtataa aaaccttgtg
    11641 tcgaatagcg gtaacccatt aactgaaaat tggtgccgaa agtgttcatt gatttcgcat
    11701 agaggaagcg aatggaatcc ccctcatgac gactgtcgtc ggctaactga ctgcgcgcat
    11761 gcgttacatc cagcgacact gcgccccagt tcccgaggtt gcgccccagc cctaacaaaa
    11821 aggcggtgta atttgcagat aattgcgtcc cgccgtaggc agtaaattcc tgtggtaaac
    11881 cgccgagtgc cgtgccctga aaaaagaaag gcgacgattg ctgactatta ccgctacgaa
    11941 aatcgcccgc cgtcaggtca aatttgaaac gcccttcgcg ttgtaaaatt ggcactgttg
    12001 aatacggaat cgtgtaattc tgctgattac catcacgctc gtcgatggtg acgtccagat
    12061 cgccatttga agatgtcggg tgcaaatctg taatttcaaa agcgccgggg gaaacatagc
    12121 tttgatagat aataaaacca ttttgccgaa tcgttagctg ggccgccgta cgggcaatcc
    12181 cacgtaccgt tggagcaaat ccctgctggc tatcaggata catattatcg gaagaataaa
    12241 gccgtacacc tcgaaatcca acgccatcga aaatatcact ccctgtatta ccgtctccca
    12301 ttaccagttc acttttcagc ggaataatgg cgcgctgtac ccaggtgcca atattattcc
    12361 actgttctga atgatatcca tttccgcgaa aataattcca ggaaccattg ttgcgtaaac
    12421 gccacgggcc aatattaatc ccgctgagtt cactaaaaaa atagctatcg ttaccattac
    12481 ctctgttacc ggtgaaatta taattcagga gtaaagcagg aataccttca tcccactctt
    12541 caggcggaat ataaccgtga gcgctactca acaacgctat ctgaggaata gtgatgttca
    12601 ggcgcatcgc tgcaaaatca aagttaattg tggcatcagg tacagctttc agtaaattga
    12661 tgcatttatt attttgctgc tgggctaact cggggaatgc actgctatta aggccaattc
    12721 gttcaaggag tgcctggtta aaacaaggca ttaacccacc tgatttatca cctgtattta
    12781 ctgtcgtcga ttcaaatacg atatcctgtg aaccaatgaa ctcatcatta cgccagagat
    12841 ccacccgata cacgcccgca ggttgatgat tacctctctc aaagtgcgat aaatcagcaa
    12901 cggatgtgcc attctctaat aaaaatgccg ggttgaaata actttccgca tagcttaaaa
    12961 aggagggtaa aatggcaaga gatgaataac aaattccggc cagacaccag gtatacctct
    13021 gcggaatatc cgtagtagtg ggtattttca taattagctc tgatattgtc agatgattcg
    13081 gttagtttaa gttcacttct ctgaccgggg ttactgaacc ataatcatta acggtctgaa
    13141 atttcagctt tccctgcact cctgagggta agggaatttg tgaattaact ctgggtgcag
    13201 ccatagcatt ccccagtttt tggctgccca cttgcaagtt aaccagggtg acataaaaag
    13261 gtgatggatt atgaacattg atatagttac cggatcgcga aaacttgagt gtgtccggcg
    13321 cttctgcggg taattcttgt aattgaattg gacggagaaa taatttcatg cgtgataaaa
    13381 tcgccagttg caaaacattc ctgccgttca atgcattttt atctaccgaa gggatcgtct
    13441 taacattcat ccagaacaga gactcacgat ctgccgccag cggtggaccg gtgtaaataa
    13501 tacgcaaagt attttcgctt ttgggttcac taacaaacag tggcggtgta atgatgaatg
    13561 acttttcttt tacaccgctg ctgttttcaa tccacgaatt gaccagaaag cgctcattgg
    13621 tatggctatt tctaatccat accgcagtct gtttagcatc agcgggataa ataatacgcg
    13681 tggcacctaa tgcgatccct ccggcagcat gggcgctgac cgaaatgatt aaataaaata
    13741 taatgagcat caataacttt attttagtca tcatagttaa tacgccttgt gtattcctga
    13801 cggcaaaaat aaggagtata aagaaatgat tgctttggtt tcttacaaca catcattccc
    13861 ttttcattta ataaagcggc atgatacaaa gtgagcgtga tttcgattta cattgccacc
    13921 ataccgcttc agacaaccgg tacattactt tgttataaga cgtgatatat aattcaaaac
    13981 aacgtggttt tgattattcg tatctcataa taaaagtcgc gtcagcattt gcttgccctg
    14041 ctgatgcact tgtaccggta cctttataac gtgcagaaaa atgaagaacg ttggtcccgg
    14101 ggatcaagtt ctggttggtt gagaagctat tcccatcagg tttgagaatt gcggatgtat
    14161 tatcaagtat ttcaataccg acacccgttg ctgttgttgt attagtactg gatgcaatgg
    14221 ccaataaatt atcattgatt gcatccgcct gaccagaaaa tgcaacggca gcattagcgg
    14281 caacgacagg atcgcagtcg ttcaactgta tagtgaatgg aattaatgca gaggtattac
    14341 caacagcatt gaaaatatcg gtacgatatt gaccgagtgt gacaacctgg tctgccgagt
    14401 cagtattcac tgaacaggca gcattcacca gttcgccttc aaagtgaatt gtaccgccat
    14461 ctacaacggc agcataacta cccgtagcgg cgaatagtgc ggcggccagc gcagacgaaa
    14521 taaatcttaa tttcatatat attccttcaa tctcatttat cgactccaca tccgtatata
    14581 accgattact ttatttaaga cactgatagt agtaaaattc ctttttatcc tctaagaatg
    14641 tcttaattga aaatatgcac tctattctaa aaaatagaga gccccgttag atgaatattt
    14701 ccgcgcaaaa tatattcaac acaaatatag acctgaagcg gt
//
LOCUS       DADXDL010000108        14489 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.108, whole genome shotgun sequence.
ACCESSION   DADXDL010000108 DADXDL010000000
VERSION     DADXDL010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14489
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.108"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(1043..1573)
                     /locus_tag="IRB70_004080"
     CDS             complement(1043..1573)
                     /locus_tag="IRB70_004080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBC0633930.1"
                     /translation="MKLTEESLNLVIDILNDLICEGKMLNDVERRSLLNAVMAITAVK
                     ERSVVSVSSRKEQSKKEKKEREIDPRFPNAGVAWNEADESLLRDVLEDVPDDEIGKHL
                     FWLAEKLGRTPYSVACKVRQIKKLPAEWKDQFRKISDRIRSSGMSVSEYLQRQGLLSP
                     ESGEENNPVSHNNNVA"
     gene            2243..2974
                     /locus_tag="IRB70_004081"
     CDS             2243..2974
                     /locus_tag="IRB70_004081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001075464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HBC0633931.1"
                     /translation="MNQPIHNDYWLSRFESILNSALVQHRAVSLIRVDLRFPEYMPVT
                     IMDPDPDSAVISRFFASLKAKIQAYQRKKRWANQRVHATSLRYFWCREFGKMYGRKHY
                     HVILLLNKDTWCSLGDFSEPSSLATMIQEAWCSALHLEPWQGDGLVHFSRWTPSRKPT
                     SSDARPSSDDTPLSGGCSDTRKASDKKPGEAAVLWIKRGDVEALQKARNRASYLVKYE
                     TKQHDGSGQRNYGCSRGPGRLLDGR"
     gene            3495..3947
                     /locus_tag="IRB70_004082"
     CDS             3495..3947
                     /locus_tag="IRB70_004082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001562078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBC0633932.1"
                     /translation="MHVINSGIRDVKFGENVKVVMPVNLYECELGDDVFIGPFVEIQK
                     GCIIGKRSRIQSHSFICENVILGDGCFIGHGVTFANDLFKCGGPDASAESWIRIVLGN
                     TVTVGSGATILTTEICSGAVIGAGSVVTKPVLVKGVYAGNPARLLRTL"
     gene            4483..5418
                     /locus_tag="IRB70_004083"
     CDS             4483..5418
                     /locus_tag="IRB70_004083"
                     /EC_number="2.7.1.83"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000332862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine kinase"
                     /protein_id="HBC0633933.1"
                     /translation="MCDKEYIITIGSANIDIAGYSYASLNYADSNPGKIKFTPGGVGR
                     NIAHNLALLGKNSWLMSAVGDDFYGQSLLAQTTQSGVNVDKCLIVNGENTSSYLSLLD
                     KTGEMLVAINDMTISEHISAEFLSQHIDFIQGAKVIVADCNISESTLVWLLNNAGKVP
                     VFVDPVSAWKCVKIREHLAQIHTLKPNRLEAETLSGISLSDRNDAEKVAVWFHTHGLN
                     RLVLSMGGDGVYYSELYGASGWSPPVKTQVVNVTGAGDAMMAGLASCWVDNMPFIDSI
                     RFAQGCSSMALASEYTNNPELSVANVKSLVEKQNV"
     gene            5411..6346
                     /locus_tag="IRB70_004084"
     CDS             5411..6346
                     /locus_tag="IRB70_004084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001292446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine-5'-phosphate glycosidase"
                     /protein_id="HBC0633934.1"
                     /translation="MSEITISSELLQISPEVQDAINSKKPVVALESTIISHGMPFPQN
                     AQTAIEVEETIRKHGAVPATIAVIGGVMKVGLSKDEIELLGREGHNVTKVSRRDLPFV
                     IAEGKHGATTVASTMIIAALAGIKVFATGGIGGVHRGAEHTFDISADLQELAHTNVTV
                     VCAGAKSILDLGLTTEYLETFGVPLIGYQTRSLPAFFCRTSPFEVSIRLDSAKEIARA
                     MAVKWQTGLNGGLVVANPIPEAYAMAEEKINAAIDQAVKEAEVQGITGKESTPFLLAR
                     VAELTGGDSLKSNIQLVFNNAVLACEIAKEYQQIV"
     gene            6430..7680
                     /locus_tag="IRB70_004085"
     CDS             6430..7680
                     /locus_tag="IRB70_004085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBC0633935.1"
                     /translation="MDIMRSIVGMAVLLIIAFLLSVNKKRISLRTTGAALVLQIAIGG
                     IMLYFPPGKWLVEQAALGVHKIMSYSDAGSAFIFGSLVGDKMDVLFDGAGFIFAFRVL
                     PAIIFVTALISLLYYIRVMGGLIRILGGIFQKALNISKVESFVAVTTIFLGQNEIPAI
                     VKPFINRLNRNELFTVICSGMASIAGSMMIGYAGMGVPIDYLLAASLMAIPGGILFAR
                     ILSPATEESKVTFENLSFTDTPPKSVIEAVASGAMTGLKIAVGVATVVMTFVAIIALI
                     NGIIGGIGGWFGYGNITLEGIFGWILAPLAWIMGVDWADASLAGSLIGQKLAINEFVA
                     YLNLSPYLQPGSTLDVKTTAIISFALCGFANFGSIGVVVGAFSAISPQRAPEIAQLGM
                     RALAAATLSNLMSATIAGFFIGLA"
     gene            complement(7699..8793)
                     /locus_tag="IRB70_004086"
     CDS             complement(7699..8793)
                     /locus_tag="IRB70_004086"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000370279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBC0633936.1"
                     /translation="MDNREKEILRILRHNPLIQQNEIAEILQISRSRVAAHIMDLMRK
                     GAIKGKGYILTEQEYCVVLGAINMDIRGVADIHYPQKSSSPGSIYCSAGGVGRNIAHN
                     LALLGRNVHLISAVGNDFYGETLLEQTRLAGVNVTNCIRLNGQNTSTYVSIADLQAET
                     VMAINDTHILQQLTPQLLDASRMLIRHAGVVLADCNLTPAALEWIFTVADGIPVFIDT
                     VSKFKAVNVKNWLPHIHTLKPTQKELEILWGSPVNNETDLLTAVNALHQQGVQQIFVW
                     MGDESVFCSQREGEQFLLTPPVHAVVDSFGADDGFMAGLLYSFLEGSSFQESAHFAMA
                     CAALSRASTSINNPTLSVNNAQYLLKTSRG"
     gene            10103..10669
                     /locus_tag="IRB70_004087"
     CDS             10103..10669
                     /locus_tag="IRB70_004087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus-type Gp2 protein"
                     /protein_id="HBC0633937.1"
                     /translation="MPKSYTPNWFFTALLDNHINQMMARYSCLRALRMDFFYRKDTPD
                     FLQPDHRWLELQLRMLLEQVEQFENIVGFFWVIEWTADHGFHAHAVLWIDRQRVKKIY
                     PFAERITECWRSITHNSGSAHRCTYQPHYTYNINIPVRHNDPESIDNIRGALHYLAKE
                     EQKDGLCAYGCNEVPERPAAGRPRNPHF"
     gene            10927..11502
                     /locus_tag="IRB70_004088"
     CDS             10927..11502
                     /locus_tag="IRB70_004088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016237504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633938.1"
                     /translation="MNAIPYFDYSLAPFWPSYQNKIIGVLERALREQSGSRIRRILLR
                     LPCEYDRTFSSRKIWFGMDFIETVSALMNATPGRDLCWLLTRHPEKPEYHVVLCVRQE
                     YFDGPELDRLILDAWSNVLGFASPGEAKQYQKQITRDVVLDSRSPDCENILKELIWAF
                     SDFARDRRGVCDPEARCLAGNPGYPGSAGPF"
     gene            11571..11804
                     /locus_tag="IRB70_004089"
     CDS             11571..11804
                     /locus_tag="IRB70_004089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HBC0633939.1"
                     /translation="MLTTTSHDSVLLRADDPLIDMNYITSFTGMTDKWFYKLISEGHF
                     PKPIKLGRSSRWYKSEVEQWMQQRIEESRGAAA"
     gene            11816..12041
                     /locus_tag="IRB70_004090"
                     /pseudo
     CDS             11816..12041
                     /locus_tag="IRB70_004090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001490840.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(12103..12369)
                     /locus_tag="IRB70_004091"
                     /pseudo
     CDS             complement(12103..12369)
                     /locus_tag="IRB70_004091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612174.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            12460..13617
                     /locus_tag="IRB70_004092"
                     /pseudo
     CDS             12460..13617
                     /locus_tag="IRB70_004092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010427625.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="efflux RND transporter permease subunit"
     gene            13738..14388
                     /locus_tag="IRB70_004093"
     CDS             13738..14388
                     /locus_tag="IRB70_004093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBC0633940.1"
                     /translation="MVRHTKFAAEETRKQILDAAEFCFCETGFSKTTLEMIAVRAGCT
                     RGAIYWYFNEKKDLLRQVIERVPLSLFDELTAIKNGRVSEPVKAMYRCLSRSLIKLQY
                     NVHLRNVIYIVFFCEECPDDIRINFLQKMVDVNNFVKLLCYIFEKGKLYREICSEIRS
                     EALAFLLFSLFTGVVRSCILQPDNKSLFREGCIVLELTQSTFTGIDKNERYYKKQR"
BASE COUNT         3768 a         3052 c         3404 g         4265 t
ORIGIN      
        1 tgcttaacgc ttacagataa taacacattc atatgagcta tatatcataa tattcaataa
       61 tcatgatatg ctaatctgat tatggataaa aattactgaa tgacgccata ttatgattgg
      121 cagtgtttcc tgtatacgat gacttatctc tcccgcatca tatgggggca cgtttcttag
      181 gaaaagtgac ggggttacag aagccaatta cgatagtttg ttgtagagtt atcacgagtt
      241 tttgttgttc tgaagacgga atcaaaaaaa taattccaga gtaaacctgt ctgttttttg
      301 accagtaaag atccatgctg gccgtgaaaa actgaaatca acactcagtc tgcatggatg
      361 tctgaagata ttgagaatgt cgggaatggt actatatacg tattatacag acatatcttc
      421 actaagtgtt atacacgcat tttcatagac aatcatacaa gtattttcat taagcattgc
      481 tgtacacatt gctttgtctg aaacacatcc agtttagtaa atttgttagt ccttttttta
      541 cgatcgctaa aatcagttaa cctcactaca aaaccctctg tcctgtttaa gcaatcaaga
      601 tgatattcga ttttactgaa cctgtgttta accttttctg agttttcgtg ttttagtcgt
      661 taacctgaga aaagtatctt tacgtaaagc ccagtgaatt aactcaaatc cgattgaggt
      721 aacctgatgc gatttactgt gagtttgcga taacactgtt aaatggctta tggatgattt
      781 tgtaacggcg agattgataa ggtgattaac tggccctggt gttttttctc agcgtaaggt
      841 gattatcttc atcataaggc tcttttcaga aaaagtgtga tgattggttg tggtgttttg
      901 attcagatga ggatctgcca atgattatga tgtattgtaa gaaataacgc cttcagaatg
      961 ttggagcatg cacttacaca aactgttttt ctaaaattaa gggaacagtt taaagagtat
     1021 aaactgttca tcttcttcag gattaagcta cattgttgtt atgactgaca ggattgtttt
     1081 cttcccctga ctctgggctt aacagtccct ggcgttgtag atattcactg actgacattc
     1141 cagaactacg gatcctgtca gagattttac gaaattgatc cttccattct gcaggtaatt
     1201 tcttaatttg tctgacttta caggctacac tgtacggggt tcgccctagt ttctctgcta
     1261 gccagaaaag gtgtttacca atttcatcgt ccggtacatc ctccagaaca tctcgcaata
     1321 aactctcgtc tgcctcattc catgccacac cagcatttgg gaaacgagga tcgatctctc
     1381 tttccttctt ctccttctta ctttgctctt ttcgggatga tacagatacg acagaacgtt
     1441 cttttaccgc tgtaattgcc ataactgcat tgagcagaga tctgcgctcc acatcgttca
     1501 gcatttttcc ttcacagatc aaatcattca ggatgtcaat gactagattc agactttctt
     1561 ctgttagctt catatttcag accttgaagt atgtagataa tcagcacaat tactaatgtg
     1621 ataaatatca gaagataatt tacaggtaaa ccggaaaata catctgaaga ataaaggcct
     1681 cagcttaacg tttcagccag tttgtgagct gattgaggta cggcgatgac attaacggga
     1741 attactcccc tatagctctg agcttatttt tcaccctggc aacatatggt ggctactgcg
     1801 catggttttg gagtagatat cttactactc gtagaattgt gcttactggt caggccagcg
     1861 cacaggcatt ccgtgcaatc aatagaacac tggtttttta gtcttccgtt acccatcagg
     1921 atgttagtgc agattccggt gtattcgatc agttgttcgg cgaatcagcg atcgatcacg
     1981 atgcgatttc gtatgttagg gatgctggta tgattactcg ctgaaaaata atgtgaaaag
     2041 gcagtttttc tttagacatt tagctcattc atgctgttgt tttacgtttt gctgtcgtgt
     2101 gcaggattat cttttcgtta cgggacgatt cattctgttt taatcaggag ccattggcgt
     2161 tgctcaatgg cgggatgccg taaagtttta ccgcagtgat taatgatgtg aagtcaatcc
     2221 aaatcaacgg agatctctca tcatgaatca accaatacac aatgattact ggttatcccg
     2281 ttttgaaagt attctcaaca gtgccctggt gcaacaccgt gccgtctcgt taatccgggt
     2341 ggatttacgt ttccctgagt atatgcctgt caccatcatg gatcccgatc cggattcagc
     2401 ggtgatttcc cgttttttcg catccctgaa agccaaaatt caggcttacc agcggaaaaa
     2461 aagatgggcc aatcagcgtg tgcatgcaac cagcctgcgt tatttctggt gccgggagtt
     2521 cggcaagatg tatggcagga aacattatca cgtgatatta ctgctcaaca aagatacctg
     2581 gtgctcgctc ggggatttca gcgaaccgtc ttcgctggcg acgatgatcc aggaggcatg
     2641 gtgcagcgcc ctgcatcttg agccctggca aggcgatggc ctggtccatt tttccaggtg
     2701 gacgccttcc cgtaaaccga catcgtctga tgctcgccct tcttccgatg acacgccttt
     2761 gtcgggtgga tgttctgata ccaggaaggc ttcagacaaa aagccaggtg aagccgctgt
     2821 gctctggatc aagcgtggtg atgtggaagc gctgcagaaa gcccggaaca gagccagtta
     2881 tctcgtgaaa tatgagacga agcagcatga cggttccggg caacgtaatt atggttgcag
     2941 tcgtgggccg gggcgtctac tggatggcag gtgaacccgg taaaacagca tccggtgcct
     3001 gagcgtatac cacggtcagg acgttggctg acgcccttag ctcgttttct gataatcgcc
     3061 ctgaagtcat gaaacggtat ttttatctgc ttccattctc atgttcatat ttccccttac
     3121 actttcactg tctgtcattg gaagtaccga tttattttgg tgctgctcac ttactgccat
     3181 tcacggaaga ggatagtggt gaaccgtacg atcctgactg ctggcgaggg aaggttcaga
     3241 actggtatga ggtttagtgc tggaagatga ctttgaatcc cggactgagc agtgaggggg
     3301 cagtgggagg atgctctggt gtaacaggcc tggattgcaa aatacaaaac cggttgtaca
     3361 ctcgtaacgg gcaaaaggat acgggcaata acacgtggta cccggtgaga caggatcttg
     3421 tatcgcatta ccgggaatat tctgacaggt gaaatgttct gataagaatc atcctgaggg
     3481 aggatacaac ggatatgcac gttattaaca gcggcattcg tgatgtgaaa tttggtgaaa
     3541 atgtgaaagt cgtcatgcca gtaaacctct atgaatgtga actgggggat gatgttttta
     3601 tcggtccctt tgtggaaata cagaagggat gcatcattgg caagcggagc cgaattcagt
     3661 cccacagttt catctgtgag aacgtcattt taggtgatgg ctgtttcatc ggtcatggcg
     3721 taacttttgc taatgatctt tttaagtgtg gtggtcccga tgcctctgca gaaagctgga
     3781 tacgtatcgt attaggtaac actgtaacag tgggtagcgg agcgactatt ttaacaacag
     3841 aaatttgcag tggagcagtg attggggctg gtagtgtggt tacaaagccc gtgctggtaa
     3901 aaggcgtgta tgccggtaat ccagccagac ttttgagaac gctttaatta ttatatttac
     3961 aaatcgtaag ccagaattga ctccagacca ttatgtgcct tattcaccat gagtgaaatg
     4021 cgggatgagc ctgcaagtta agaggatatc ggaaaccagc aaccagggca gtgagagcgc
     4081 tgtcggggtc attgatatct ccgaagggaa gccctggtat aaggtgtttg cataaaatta
     4141 ttaaacaggc tcatttttag cgatcctcat gaaattcatc gtaacatcct gaatatctta
     4201 tggtgtttcc tgtcatctcc ggtatttatt ccgttcatgc aaataacctg atgaaacagg
     4261 gcaacgccat aaaaccggat aaggacaaca tggattaacg ataaaaattg tgatcctgtt
     4321 ttcatttttc actttttgat tctggactgg tatttacatt tctaaaaaca ggcataaagt
     4381 gaacacatgt ttgattttga atatatgttc aactctatct gcgtggtcga atagaaatac
     4441 agatttatta tttttgtgtt tttaaatgtc aggagatgtg ccatgtgtga taaggaatac
     4501 atcatcacaa ttggctctgc caatatagat atagccggat attcgtatgc ctccttaaat
     4561 tatgctgatt ctaacccggg gaagattaaa ttcacgcccg gaggtgtggg gcgtaatatt
     4621 gcacataatc ttgctctgct gggtaaaaac tcatggctga tgtcagctgt gggagatgat
     4681 ttctacgggc aatcattatt agcacaaacg actcagtccg gcgttaatgt tgataaatgt
     4741 ctgattgtta atggagaaaa tacctcaagt tatttatcac ttctcgataa aaccggtgaa
     4801 atgttggtgg caataaatga catgacgatt agtgaacata tttcagctga gtttttatca
     4861 cagcatattg attttattca gggagcgaag gttattgttg cagactgtaa tatcagtgag
     4921 tcaacacttg tctggctact gaataatgca ggtaaggttc cggtatttgt tgacccggta
     4981 tctgcatgga agtgtgtcaa aattcgtgaa catttagcac aaattcatac tctcaagccc
     5041 aaccggcttg aagcagaaac actcagtggt atttcgcttt cagatcggaa tgatgctgaa
     5101 aaagtggcgg tatggttcca tacacatggt ctgaatcgcc ttgtgctcag catggggggg
     5161 gatggagttt attacagcga actgtacgga gccagcggct ggtcgccgcc agtaaaaaca
     5221 caggtggtga acgttacggg ggcaggggat gccatgatgg cagggctggc ttcctgctgg
     5281 gttgataata tgccatttat tgattccatt cgatttgcac aggggtgttc atcaatggcg
     5341 ctggccagtg agtataccaa taatcctgaa ttatctgttg ctaacgttaa aagcttagtg
     5401 gagaaacaga atgtctgaaa taaccatttc ttctgaatta ctgcaaattt caccggaagt
     5461 acaggatgcc attaacagta aaaaacctgt tgttgctctc gagtcaacaa ttatctcaca
     5521 tggtatgcct tttcctcaga atgctcagac ggctattgaa gtcgaagaaa ctatacgtaa
     5581 acacggagca gtaccagcca ccattgccgt tattggcggt gtaatgaaag tcgggttaag
     5641 taaagatgag attgaattac tgggtcgcga aggacataac gttaccaaag tcagtcgccg
     5701 ggatttacct ttcgttattg ctgaaggaaa acatggtgca acaacggtag cttcaaccat
     5761 gattattgct gctcttgccg gaattaaagt ttttgccaca ggaggaattg gcggcgttca
     5821 tcgcggtgca gaacacactt ttgatatttc agccgaccta caggaactgg cacatactaa
     5881 tgtcaccgtg gtttgtgcag gcgcgaaatc cattctcgat ttagggttaa ccacggaata
     5941 tttagaaaca tttggtgtac ctttaattgg ctatcagaca agatcattgc cggcattttt
     6001 ttgccgcacc agtccgtttg aggtcagtat acgtctggac agtgcaaaag agattgcccg
     6061 cgcgatggca gtgaaatggc aaaccggcct gaacggtggt ctggttgttg ccaatccgat
     6121 tccggaagct tacgccatgg cggaagagaa aattaatgca gcaattgacc aggccgtaaa
     6181 agaagcggaa gtgcagggca ttaccggtaa agaaagcaca ccgttcctgc tggcacgggt
     6241 ggcagaatta accggtggtg acagtctgaa atcaaatatt cagctggtat tcaacaacgc
     6301 agttctggcc tgtgagatag caaaagaata tcaacaaatt gtctgatata aatgaacggg
     6361 cagtgtgagg tcgcccgaaa ttacctgaac cagattccgt gtctggttca ggtataaggg
     6421 gagagcatta tggacatcat gagaagtata gtgggaatgg cagtattgct gataattgca
     6481 tttctactat cagtgaataa aaaacgtatc agtttacgta ccacaggagc tgcactggtt
     6541 cttcaaatcg cgattggtgg gatcatgctc tatttccccc cggggaaatg gctggttgaa
     6601 caggctgcac tgggcgtaca taaaattatg tcttacagtg atgcgggcag tgcctttatt
     6661 tttggctctc tggtagggga caaaatggac gtactgttcg atggggcggg ttttatcttc
     6721 gccttccgtg tacttcctgc catcattttt gttacagcgc ttatcagtct gctgtactac
     6781 atcagagtga tgggggggct tatccgtatt ctggggggga tttttcagaa agctctgaac
     6841 ataagtaaag ttgagtcatt tgtggcagta acgacaattt tcctggggca aaacgagatc
     6901 ccggcaattg taaaaccgtt tattaatcgt ctgaatcgta atgaattatt tactgtcatc
     6961 tgcagtggga tggcttcgat tgccggttca atgatgatcg gctatgccgg gatgggggtt
     7021 ccgattgact atttgctggc ggcgtcgttg atggcgatcc cgggggggat cctttttgcc
     7081 cgtattctga gtccggccac agaagaatca aaagtcactt ttgaaaatct ttctttcact
     7141 gatactcctc ccaaaagtgt tattgaagca gtggccagcg gggcgatgac cgggttgaaa
     7201 atcgctgtcg gagttgcaac ggtagtgatg acctttgttg ctattattgc tctgattaac
     7261 ggtataatcg gtggtatcgg aggctggttt ggttatggta atattaccct tgagggcatt
     7321 ttcggctgga ttttggctcc ccttgcgtgg atcatgggcg ttgactgggc ggatgcttca
     7381 ctggcaggaa gtctgattgg tcagaagctg gcaattaacg aatttgttgc ttatctcaat
     7441 ctttcaccct atttacagcc aggcagtacg cttgatgtga aaaccaccgc aattatttct
     7501 tttgcactgt gtggttttgc caactttggc tccattggtg tggtggtggg tgccttttca
     7561 gccatatcac ctcagcgtgc acctgaaatt gcacaactgg gcatgcgtgc actggcggcg
     7621 gccaccctgt caaacctgat gagtgcgact atcgctggtt ttttcattgg gctggcataa
     7681 aaaatacaat cccgggtgtt acccccggga tgtttttaac agatattgcg cgttattaac
     7741 ggaaagtgtt gggttattga tgctggtgct ggcacgtgac agtgctgcac atgccatcgc
     7801 aaagtgagca ctttcctgga aactacttcc ttccagaaaa ctgtaaagca gacctgccat
     7861 aaagccatca tctgcaccaa agctgtccac aacggcatga acgggcggtg tgagcagaaa
     7921 ttgttctccc tctctttggc tacagaaaac ggattcatct cccatccaga caaaaatctg
     7981 ttgcacaccc tgctgatgta gtgcgttcac tgcggtgagt agatcggtct cattgttgac
     8041 aggggaaccc cataatatct ccagttcttt ttgtgtgggt ttcagggtat ggatatgcgg
     8101 aagccagttt tttacattaa cagccttaaa tttcgacact gtatcaataa aaacgggaat
     8161 gccgtcagcg accgtaaaga tccattcaag ggcggcaggt gtcagattac agtcagccag
     8221 caccacgcca gcgtgacgga ttaacatacg tgaggcgtcc agcaactgcg gcgtcagttg
     8281 ttgcagaata tgggtatcat taatcgccat cactgtttct gcctgtaggt cggcgatgga
     8341 gacataagtt gaagtatttt gtccgttcag tcgaatacaa ttggtgacat taacgccggc
     8401 caggcgggtc tgctccagta atgtttcgcc ataaaaatca ttgcctacag cagatatcag
     8461 atgcacattg cggcccagaa gggcgagatt atgggcgatg ttgcgtccga cacctccggc
     8521 agagcagtaa atactgcccg gactggagga tttctgtgga taatggatat ccgccacccc
     8581 acggatatcc atgttaatcg ccccaagaac aacacagtat tcctgttctg tcaggatgta
     8641 gcctttccct ttaatcgcac ctttgcgcat cagatccata atgtgtgcag caacacgcga
     8701 ccgactgatt tgtaaaatct cagcaatttc attctgctgg atcagtgggt tgtgacgcag
     8761 gatcctgagt atctcttttt ctctgttgtc catgattatg caactgcctg ttcggttttt
     8821 cgtcagcgat catcaaagta aatagcttcg tttttcccgg tgaacgtgaa gctaggggag
     8881 attatacttc cggatgttca ttcagggcag aagaataata catcagttaa ttttctgtta
     8941 gtactttgta gtcgaatgtt tggggagtgt gtctgaatga cagccagatg gaatgacttt
     9001 ttgtagccag gtcatgacta cgactcatac gctattctta attcttattt ctttccatta
     9061 tacgcaagta tttttaattt aggtttatta ctataattat attcactttg tctttattca
     9121 ctctgttttt acttactctc tatctttact cattccatta ctctgaccct cacccgatta
     9181 tacttactcc cttccttgtc taatcttcat tgccaccatt atcatggtat ccaccttctc
     9241 caccttctcc accttctcca ccttctcctt cattcaatca taactactgt aattcatacg
     9301 atactcagat aagttatttt actacgttgt tgctaatatc tacctgttat cagtcttcac
     9361 tgaaacagca attgatttta gtcattatcc ataatgaact gtattgactt aacgatgatt
     9421 gttgttgacc tgaagtgttt taactattct ggtaaatatc aatacttctg tcatcactga
     9481 ttaactggat gtttactctt tgataaggta tccatgattt cgtcatgttt aacagcgcag
     9541 gataaacaat gaaattaaca gagtgaattc ctgattatat ttgttcgttt ctgattatct
     9601 tgtatgttaa acaaaatgaa aattatccat ccatggtata ttttattctg gtaccgtgta
     9661 cccgttaacg ctcatgtttt gaagtgagtt gtttttaaca gattaaatga gagtgtatga
     9721 ttttatcagg ttacagatat gtgttggcct tgtacacgtt tttgcagact cactgagagc
     9781 aagtttgtag tttatgatgt gattggtcgc aatatgtttc ttaatctcca ggtagtgggg
     9841 ttttagctcg tattttacag tatttcgtga tgttttattg agtctgtatt ttctttactc
     9901 ctcgtttatc tcatctcttt agctaatacc atcagataat ccatttcttt ctgcataatg
     9961 ctgcgtatcg ttaataaccc gtcgtatcca ttctgctaca gcatgcctga taaataccat
    10021 ctgtaagtta ttaccgttat gagcgaaagc attaattcgt tcacagagct taaaacatca
    10081 ttaactttca ggagtcatca acatgcctaa atcttacaca ccaaactggt tttttaccgc
    10141 tttacttgac aatcacatca atcaaatgat ggcacgctat tcctgcctgc gggccttacg
    10201 gatggatttc ttctacagga aagatacgcc cgatttctta caacctgatc atcgctggct
    10261 tgaattgcag ttgcgtatgc tgctggagca ggtggaacaa tttgaaaata tcgttggttt
    10321 cttctgggtg attgaatgga cggctgatca tggttttcat gcgcatgcgg ttttgtggat
    10381 cgatcgtcag agggttaaaa aaatatatcc ctttgcggag cggattacgg aatgctggcg
    10441 gtctattaca cataacagcg gttcggcaca ccgctgtaca tatcagccgc attatacata
    10501 caacatcaac attcctgtgc gccacaacga tcctgaaagc atcgataata ttcgcggtgc
    10561 cctgcattat ctggcaaaag aagagcaaaa agacgggctg tgtgcctacg gctgcaatga
    10621 agttcctgaa cgtcctgctg cagggcgtcc tcgtaaccct cacttctgaa gcttaaatcc
    10681 tgagcttcct gtcctggaaa cattccgtcg gtaaaacctt accaccttgc ttaatgatgt
    10741 gaactgaagt caacggagat cattcactct taaccacatc cggtgttctg tcccttgtcg
    10801 gtgacctgat cttcccgttc tgcttcggtt cttcacttat tccatcaacc ccatccgcaa
    10861 gctataacac gtcagctcat tcacgggcag gacgcattgt gggctgcgca taacggagca
    10921 tatcttatga atgctatccc ttatttcgac tatagcctgg cacccttctg gccgtcttat
    10981 cagaacaaaa tcatcggtgt ccttgagcgt gcgctgcgtg agcagtccgg ctcccggata
    11041 cgacggatcc tgcttcgtct gccatgtgaa tatgaccgta ccttcagcag cagaaagatc
    11101 tggttcggta tggactttat cgaaaccgtc agtgcgctga tgaatgcaac acctggacga
    11161 gatctctgct ggctcctgac ccgtcatcct gaaaagccgg aataccacgt ggtgctgtgt
    11221 gtcagacagg agtatttcga cggccctgaa ctggaccggc tgattctgga tgcctggagc
    11281 aacgtactgg gcttcgcgtc accgggtgaa gcaaagcagt atcagaagca gatcacccgg
    11341 gatgtggtgc tggacagtcg ttcaccggac tgtgaaaaca tcctcaaaga gttgatatgg
    11401 gcgttcagtg atttcgcccg cgatcgtcgt ggtgtgtgcg atccggaagc ccgttgcctc
    11461 gccggtaatc ccggctatcc cggatctgca ggaccgttct gaaagctcgg ttcagcatct
    11521 ttccctgcat tcgcacaaac ttcataaatc tcacaaagga cattctgacc atgttgacca
    11581 caacaagcca cgacagcgtg ttactgcgtg ccgacgatcc cctgatcgac atgaactaca
    11641 tcaccagttt caccggtatg accgataaat ggttttacaa gctgatcagt gaaggtcatt
    11701 tccctaaacc catcaaactg gggcgcagca gccgctggta caaaagtgaa gtggagcagt
    11761 ggatgcagca gcgaattgag gaatcacgag gagcagcagc atgaaacgtg ttgcaatgcc
    11821 ggcgctggta ttgcggaaat cagccctgtc cccgatgctg gcgacactcc cgctcatctt
    11881 tctgctgact cctctggtct gccaactgtt tgtcatcatt tcctgactga ttcgtcattc
    11941 ccttcgtccc gccagtcact ggtgtttgta tcgtaccgtc cggtgttgat gtgcgttttc
    12001 cgtgtgtctg caccggctta acaaaattca acagggtttg aaaaggaaca tttcgtgcaa
    12061 ataaccgaag ccttaatttc agagccggga gacatccggc gttttgttca gcaggcgctg
    12121 gagttcttta atctgcttca tggcagcagc aagttcagag gcaggaacga cctgttctcc
    12181 tgcggccaca gcagtaagac ttccctcctg gtattgcttg cgccagagaa ataactggct
    12241 ggctgccaca ccgtgttgcc gggcaacaag ggagaccgtc attcccggct caaagctctg
    12301 ctgaacaata gcgatctttt cctgtgtagt acgccgtctg cgtttctccg gtcctaagac
    12361 atcaatcatc tgttctccaa tgactagtct aaaaactagt attaagacta tcacttattt
    12421 aagtgatatt ggttgtctgg agattctggg ggctagtcta gttttaaaac gccccctgcc
    12481 gtatcagaac tggggaatgc tacagggttt gacctgttcc tcgaggatcg tagcggagct
    12541 ggccatgaaa aaatgatcca ggcccgaaat cagcttcttg ctgaagcggc gaaaagtcca
    12601 gcgttaaaca tggttcgtcc taacggcatg aacgatgagc ctcagttcca gattctgatt
    12661 gatgacgaga aagttcaggc gcttaaactg agcatgagcg acgtcgacaa cataatgtca
    12721 gcagcctggg gttcgatgta tgtaaatgat tttaacgatc gtggacgggt gaaaaaagtc
    12781 tatatttagg gcgaacccgg ctcacgtata tcaccgcagg attttgataa atggtatgtc
    12841 cgtaacagtg atggcgacat ggtttccttt gcctcttttg caacaggcaa atggatttat
    12901 ggctcaccaa aactggagca atataatggt atctctgctg tcgaaatcct gggggaaccg
    12961 gcaccaggat acagttccgg ggatgcaatg aaagcaattg aggatattgc ggcaagactt
    13021 cccgaaggtt tccatatttc ctggacaggt ttgtcttttg aggaacgact ttcaggttct
    13081 caggctcctg cactatatgc actttcactg ttgatcgtct ttctgtgtct ggctgcactg
    13141 tatgaaagct ggagcattcc tttctcggtc atgctggttg ttccgcttgg tgtcctgggg
    13201 gctgtctgtg ctactttgtt gcgcggcctt ggtaacgatg tctttttcca ggtcggttta
    13261 ttaacaacaa tagggctgtc tgcgaaaaat gccatactta tcgtggagtt tgctcgtgaa
    13321 ttgcatgaga aagaaggact aagcattaaa gaggctgctg ttgaagcggc gagagtgagg
    13381 ttaagaccga taattatgac ttcgctggca tttgtaatgg gggttatccc actggctgtc
    13441 tcgactggag caagttccgg aagtaaacat gccatcggta ctggtgtggt tggagggatg
    13501 atcactgcta cgatactggc aatcttttat attcctctct tctatatgtt aattgccggg
    13561 ttcttcagcc gcagaaataa gaaatcatcg gataagactg aagctgagca atcataagca
    13621 tgagtaaata ttcaggtgca gtaaacaaca tactgcgcct gagtaaatgg ctgttgggtt
    13681 ggtactaaat gccccagaga tatttcctga aataagatgt caatggagat ttcaacagtg
    13741 gtgcggcaca caaaatttgc agcggaagaa acccgcaaac aaatcctgga tgcggcagag
    13801 ttctgctttt gtgagacggg cttttcgaag acgacactgg agatgattgc ggtgcgcgca
    13861 ggttgtactc ggggggccat atactggtat ttcaacgaaa aaaaagatct tctgcgacaa
    13921 gtcatcgagc gggtaccact atcattattt gatgagctta cagccatcaa aaatgggaga
    13981 gtttctgaac cggttaaagc gatgtatcgt tgcttatcac gtagcctgat taaattacaa
    14041 tataatgtac acttacggaa tgtaatttat attgtgtttt tttgtgaaga atgtccggat
    14101 gatataagaa taaatttctt acaaaaaatg gtggatgtca ataattttgt gaaattacta
    14161 tgttatattt tcgaaaaagg taagttatat agagaaatat gttcggaaat tcgtagtgag
    14221 gctctggcgt tcctgctttt ttctttgttt acgggggtgg tgcgaagttg cattctgcaa
    14281 cctgataata aatccctttt cagagagggt tgcatagtac tggagttgac ccaatcaacc
    14341 ttcacaggca tcgataaaaa tgaacgctac tataaaaaac agcgctgata tcaatgagct
    14401 tgctaaatga attgatgaaa atcttgaggt agaactctca ataaatattg aggcaaaaaa
    14461 gctggatatt caaaatggta tttacagaa
//
LOCUS       DADXDL010000109        14479 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.109, whole genome shotgun sequence.
ACCESSION   DADXDL010000109 DADXDL010000000
VERSION     DADXDL010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14479)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14479)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14479
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.109"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..800
                     /locus_tag="IRB70_004094"
     CDS             <1..800
                     /locus_tag="IRB70_004094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
                     /protein_id="HBC0633941.1"
                     /translation="WGDDIAKTRHQINLSNSTSFSKDGYSSNNTGITGIAGEHDQLNY
                     GIYVNQQQQNNDTSLGTNLSWRTPIAIIDGSYSHSKNAWQSGGSISSGLVVWPGGINI
                     TNQLSDTFAILDAPGLEGANINGQKYNRTNSKGQVVYDLIIPHRENHLVLDIANSESE
                     TELQGNRQIIAPYRGAVSYVQFTTDQRKPWYIQALRPDGSPLTFGYDVLDLQENNIGV
                     VGQGSRLFIRVDEIPTGIKVALNDEQNLFCTITFQHVIDENKTYICQ"
     gene            813..1772
                     /locus_tag="IRB70_004095"
                     /pseudo
     CDS             813..1772
                     /locus_tag="IRB70_004095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000871680.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial family protein"
     gene            complement(1811..2710)
                     /gene="nhaR"
                     /locus_tag="IRB70_004096"
     CDS             complement(1811..2710)
                     /gene="nhaR"
                     /locus_tag="IRB70_004096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705976.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional activator NhaR"
                     /protein_id="HBC0633942.1"
                     /translation="MSHINYNHLYYFWHVYKEGSVVGAAEALYLTPQTITGQIRALEE
                     RLQGKLFKRKGRGLEPSELGELVYRYADKMFTLSQEMLDIVNYRKESNLLFDVGVADA
                     LSKRLVSSVLNAAVVEGEPIHLRCFESTHEMLLEQLSQHKLDMIISDCPIDSTQQEGL
                     FSVRIGECGVSFWCTNPPPEKPFPACLEERRLLIPGRRSMLGRKLLNWFNSQGLNVEI
                     LGEFDDAALMKAFGAMHNAIFVAPTLYAYDFYADKTVVEIGRVENVMEEYHAIFAERM
                     IQHPAVQRICNTDYSALFSPAAR"
     gene            complement(2776..3942)
                     /gene="nhaA"
                     /locus_tag="IRB70_004097"
     CDS             complement(2776..3942)
                     /gene="nhaA"
                     /locus_tag="IRB70_004097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaA"
                     /protein_id="HBC0633943.1"
                     /translation="MKHLHRFFSSDASGGIILIIAAILAMIMANSGATSGWYHDFLET
                     PVQLRVGSLEINKNMLLWINDALMAVFFLLVGLEVKRELMQGSLASLRQAAFPVIAAI
                     GGMIVPALLYLAFNYADPITREGWAIPAATDIAFALGVLALLGSRVPLALKIFLMALA
                     IIDDLGAIIIIALFYTNDLSMASLGVAAVAIAVLAVLNLCGVRRTGVYILVGVVLWTA
                     VLKSGVHATLAGVIVGFFIPLKEKHGRSPAKRLEHVLHPWVAYLILPLFAFANAGVSL
                     QGVTLDGLTSILPLGIIAGLLIGKPLGISLFCWLALRLKLAHLPEGTTYQQIMAVGIL
                     CGIGFTMSIFIASLAFGNVDPELINWAKLGILVGSISSAVIGYSWLRVRLRPSV"
     gene            4528..4680
                     /gene="mokC"
                     /locus_tag="IRB70_004098"
     CDS             4528..4680
                     /gene="mokC"
                     /locus_tag="IRB70_004098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin MokC"
                     /protein_id="HBC0633944.1"
                     /translation="MKQHKAMIVALIVICITAVVAVLVTRKDLCEVHIRTGQTEVAVF
                     TAYESE"
     gene            complement(4784..5914)
                     /gene="dnaJ"
                     /locus_tag="IRB70_004099"
     CDS             complement(4784..5914)
                     /gene="dnaJ"
                     /locus_tag="IRB70_004099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308042.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBC0633945.1"
                     /translation="MAKQDYYEILGVSKTAEEREIKKAYKRLAMKYHPDRNQGDKEAE
                     AKFKEIKEAYEVLTDSQKRAAYDQYGHAAFEQGGMGGGGFGGGADFSDIFGDVFGDIF
                     GGGRGRQRAARGADLRYNMELTLEEAVRGVTKEIRIPTLEECDVCHGSGAKPGTQPQT
                     CPTCHGSGQVQMRQGFFAVQQTCPHCQGRGTLIKDPCNKCHGHGRVERSKTLSVKIPA
                     GVDTGDRIRLAGEGEAGEHGAPAGDLYVQVQVKQHPIFEREGNNLYCEVPINFAMAAL
                     GGEIEVPTLDGRVKLKVPGETQTGKLFRMRGKGVKSVRGGAQGDLLCRVVVETPVGLN
                     EKQKQLLQELQESFGGPTGEHNSPRSKSFFDGVKKFFDDLTR"
     gene            complement(6003..7919)
                     /gene="dnaK"
                     /locus_tag="IRB70_004100"
     CDS             complement(6003..7919)
                     /gene="dnaK"
                     /locus_tag="IRB70_004100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001737966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBC0633946.1"
                     /translation="MGKIIGIDLGTTNSCVAIMDGTTPRVLENAEGDRTTPSIIAYTQ
                     DGETLVGQPAKRQAVTNPQNTLFAIKRLIGRRFQDEEVQRDVSIMPFKIIAADNGDAW
                     VEVKGQKMAPPQISAEVLKKMKKTAEDYLGEPVTEAVITVPAYFNDAQRQATKDAGRI
                     AGLEVKRIINEPTAAALAYGLDKGTGNRTIAVYDLGGGTFDISIIEIDEVDGEKTFEV
                     LATNGDTHLGGEDFDSRLINYLVEEFKKDQGIDLRNDPLAMQRLKEAAEKAKIELSSA
                     QQTDVNLPYITADATGPKHMNIKVTRAKLESLVEDLVNRSIEPLKVALQDAGLSVSDI
                     DDVILVGGQTRMPMVQKKVAEFFGKEPRKDVNPDEAVAIGAAVQGGVLTGDVKDVLLL
                     DVTPLSLGIETMGGVMTTLIAKNTTIPTKHSQVFSTAEDNQSAVTIHVLQGERKRAAD
                     NKSLGQFNLDGINPAPRGMPQIEVTFDIDADGILHVSAKDKNSGKEQKITIKASSGLN
                     EDEIQKMVRDAEANAEADRKFEELVQTRNQGDHLLHSTRKQVEEAGDKLPADDKTAIE
                     SALTALETALKGEDKAAIEAKMQELAQVSQKLMEIAQQQHAQQQTAGADASANNAKDD
                     DVVDAEFEEVKDKK"
     gene            8296..8700
                     /locus_tag="IRB70_004101"
     CDS             8296..8700
                     /locus_tag="IRB70_004101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_705972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2541 family protein"
                     /protein_id="HBC0633947.1"
                     /translation="MKSVFTISASLAISLMLCCTAQANDHKLLGVIAMPRNETNDLAL
                     KLPVCRIVKRIQLSADHGDLQLSDASVYFKAARSASQSLNIPSEIKEGQTTDWININS
                     DNDNKRCVSKITFSGHTVNSSDMATLKIIGDD"
     gene            8726..9439
                     /gene="msyB"
                     /locus_tag="IRB70_004102"
     CDS             8726..9439
                     /gene="msyB"
                     /locus_tag="IRB70_004102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acidic protein MsyB"
                     /protein_id="HBC0633948.1"
                     /translation="MNVNYLNDSDLDFLQHCSEEQLANFARLLTHNEKGKTRLSSVLM
                     RNELFKSMEGHPEQHRRNWQLIAGELQHFGGDSIANKLRGHGKLYRAILLDVSKRLKL
                     KADKEMSTFEIEQQLLEQFLRNTWKNMDEEHKQEFLHAVDARVNKLEELLPLLMKDKL
                     LAKGVSHLLSSQLTRILRTHAAMSVLGHGLLRGAGLGGPVGAALNGVKAVSGSAYRVT
                     IPAVLQIACLRRMVSATQV"
     gene            9588..10154
                     /gene="satP"
                     /locus_tag="IRB70_004103"
     CDS             9588..10154
                     /gene="satP"
                     /locus_tag="IRB70_004103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate uptake transporter"
                     /protein_id="HBC0633949.1"
                     /translation="MGNTKLANPAPLGLMGFGMTTILLNLHNVGYFALDGIILAMGIF
                     YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKLGLTDAPNAQFLGVY
                     LGLWGVFTLFMFFGTLKGARVLQFVFFSLTVLFALLAIGNIAGNAAIIHFAGWIGLIC
                     GASAIYLAMGEVLNEQFGRTVLPIGESH"
     gene            complement(10189..10776)
                     /gene="mog"
                     /locus_tag="IRB70_004104"
     CDS             complement(10189..10776)
                     /gene="mog"
                     /locus_tag="IRB70_004104"
                     /EC_number="2.7.7.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin adenylyltransferase"
                     /protein_id="HBC0633950.1"
                     /translation="MNTLRIGLVSISDRASSGVYQDKGIPALEEWLTSALTTPFELET
                     RLIPDEQAIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAVADREMPGFGEQ
                     MRQISLHFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKDAEGNVVVHGIFA
                     SVPYCIQLLEGPYVETAPEVVAAFRPKSARRDVSE"
     gene            complement(10891..11844)
                     /gene="tal"
                     /locus_tag="IRB70_004105"
     CDS             complement(10891..11844)
                     /gene="tal"
                     /locus_tag="IRB70_004105"
                     /EC_number="2.2.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transaldolase"
                     /protein_id="HBC0633951.1"
                     /translation="MTDKLTSLRQYTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
                     IPEYRKLIDDAVAWAKQQSNDRAQQIVDATDKLAVNIGLEILKLVPGRISTEVDARLS
                     YDTEASIAKAKRLIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
                     FAQARACAEAGVFLISPFVGRILDWYKANTDKKEYAPAEDPGVVSVSEIYQYYKEHGY
                     ETVVMGASFRNIGEILELAGCDRLTIAPALLKELAESEGAIERKLSYTGEVKARPARI
                     TESEFLWQHNQDPMAVDKLAEGIRKFAIDQEKLEKMIGDLL"
     gene            12123..13553
                     /locus_tag="IRB70_004106"
     CDS             12123..13553
                     /locus_tag="IRB70_004106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:alanine symporter family protein"
                     /protein_id="HBC0633952.1"
                     /translation="MPDFFSFINSVLWGSVMIYLLFGAGCWFTFRTGFVQFRYIRQFG
                     KSLKNSIHPQPGGLTSFQSLCTSLAARVGSGNLAGVALAITAGGPGAVFWMWVAAFIG
                     MATSFAECSLAQLYKERDVNGQFRGGPAWYMARGLGMRWMGVLFAVFLLIAYGIIFSG
                     VQANAVARALSFSFDFPPLVTGIILAVFALLAITRGLHGVARLMQGFVPLMAIIWVLT
                     SMVICVINIGQLPHVIWSIFESAFGWQEAAGGAAGYTLSQAITNGFQRSMFSNEAGMG
                     STPNAAAAAASWPPHPAAQGIVQMIGIFIDTLVICTASAMLILLAGNDTTYMPLEGIQ
                     LIQKAMRVLMGSWGAEFVTLVVILFAFSSIVANYIYAENNLFFLRLNNPKAIWCLRIC
                     TFATVIGGTLLSLPLMWQLADIIMACMAITNLTAILLLSPVVHTIASDYLRQRKLGVR
                     PVFDPLRYPDIGRQLSPDAWDDVSQE"
     gene            13623..14399
                     /gene="yaaA"
                     /locus_tag="IRB70_004107"
     CDS             13623..14399
                     /gene="yaaA"
                     /locus_tag="IRB70_004107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxide stress protein YaaA"
                     /protein_id="HBC0633953.1"
                     /translation="MLILISPAKTLDYQSPLTTTRYTLPELLDNSQQLIHEARKLTPP
                     QISTLMRISDKLAGINAARFHDWQPDFTPENARQAILAFKGDVYTGLQAETFSEDDFD
                     FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENARGKDLYQFWGDIITNKLNEALA
                     AQGDNVVINLASDEYFKSVKPKKLNAEIIKPVFLDEKNGKFKIISFYAKKARGLMSRF
                     IIENRLTKPEQLTGFNTEGYFFDEASSSNGELVFKRYEQR"
BASE COUNT         3632 a         3615 c         3451 g         3781 t
ORIGIN      
        1 actgggggga tgatattgcc aaaacacgtc accaaattaa cttatcgaat tcgacctcat
       61 tttccaaaga tggctattcc tccaacaata ctggaattac tggcatagcc ggtgaacatg
      121 atcagttaaa ttatggtata tatgttaatc agcaacaaca aaataatgat acctcgcttg
      181 gtacgaattt aagctggaga actcccatcg ccataataga tggcagctat agtcattcta
      241 aaaacgcctg gcaaagtggt ggaagtatta gtagtggatt agttgtctgg cccggtggta
      301 ttaatatcac taaccagtta tccgatacat ttgcaattct ggatgcgcct gggttagaag
      361 gtgcgaatat taatggacaa aaatacaatc gaacaaacag caaaggccag gttgtttacg
      421 acctgataat acctcatcgt gaaaaccatc tggtacttga tatagcaaac agtgaaagtg
      481 aaacagaatt gcagggcaat cgtcaaatta ttgcacctta ccgtggagca gtttcttatg
      541 tgcagtttac aactgaccaa cgtaagccct ggtatataca ggcactgcgt cccgatggtt
      601 cgccattaac ctttggctat gacgtactgg atctccagga aaataatatt ggagtcgttg
      661 gccagggtag tcgccttttt attcgcgtag atgaaattcc cactggaata aaagttgctc
      721 tcaatgatga acagaactta ttctgtacta ttacttttca acacgttatc gatgaaaaca
      781 aaacatatat atgccagtaa aaggagttta ctatgaagtg gcttttatta atcaccttga
      841 gtctatattc ttttattgtg caaagtgctc cctgtgcatt gaccaatgtc ggggaacaac
      901 gtggaacata tatactcaag ccactgagta tgaaaggtaa tctcaccgcc gaaaaaattg
      961 aaaacaccgg aaatatcatt gagtgtgcag acttacaaga gacgaccaac gccattaaag
     1021 ttcatttttt aacacagaac gctttaaggt ttaaagtcgg aagtcgtcat tatattatta
     1081 atttcccctt tgaatctgac ggtaaaaaaa tagagcttcc aggaaggtca tcttataatt
     1141 tagaagaaat gctatctgcg ataaatttca ccattccata ctctatcgca tctgtatcag
     1201 atagttccaa caccgcagat atttttccag gaactccttt tcctttgttg ttcgaaattg
     1261 aagtgagttc atgtacaggg aataatacta attgtaatag cgtccgcttt aattataatt
     1321 taaatactat tttacaggta aatttaatga cctgtggttt tgaagatcaa tccatcgaca
     1381 ctggacgatt tgtactgtct cgtatcaata atgaaaatta tcagtttcat catataagat
     1441 ttgactgcat ccagggcgag caaggtgaat tagtttttga acccagtgat gttgaatatt
     1501 actttgaacc agtgacgata caggagtcag gaaccagcat attaaaaaat gagttagaaa
     1561 acagtgagga cggtgcgggt caagtaggct tttaactctc caatgatggt acgaatgaaa
     1621 tccagtatgg taaaagcaat tactactctt ttcagcatcc ccatgaagga agtaatcaga
     1681 ttcctctatt tattcgcccg cgtacatatg gaaataatgt ctcaagcggg caaataatga
     1741 gccgagtcaa aatcgtggtt atgtacaact aatctatctc ccccacctta actttggggg
     1801 gaggtgccga ttaacgcgcc gctggactaa aaagcgcaga ataatccgta ttgcagattc
     1861 gctgtaccgc cgggtgctga atcatccgct cagcaaaaat agcatggtac tcttccatca
     1921 cattctcgac gcgaccaatt tctacgacag ttttatcggc ataaaagtca tatgcataaa
     1981 gcgttggggc aacgaagatt gcattgtgca tcgcaccaaa agctttcatc aacgcggcat
     2041 catcaaactc gccgaggatt tctacgttta atccctggga gttaaaccag ttaagcaatt
     2101 tgcgccctaa cattgaacgt cgcccaggaa tcaaaagtcg ccgttcttcc agacaagccg
     2161 ggaacggttt ttctggtggt ggatttgtac accagaaact cacgccacat tcgccaattc
     2221 tcacggagaa caggccttcc tgctgcgtag agtctatcgg acagtcagaa atgatcatat
     2281 ccagtttatg ctgacttaat tgctccagca gcatttcgtg ggtggattcg aagcagcgaa
     2341 gatgaatggg ctcgccttct accactgcgg cgttaagtac gctactgacc aggcgtttgg
     2401 aaagtgcatc agccacacca acgtcaaaca ataaattgga ttctttgcga tagttcacaa
     2461 tatccagcat ttcctggctt aaggtgaaca ttttatcggc atagcgatag accagttctc
     2521 ccagctcgct gggttcgaga ccacgtccct tgcgtttaaa taatttgcct tgcaggcgct
     2581 cttccagcgc tcgaatctgt ccggtaatgg tttgtggagt taaataaagc gcctccgctg
     2641 cgccaaccac ggaaccttct ttatagacat gccagaagta atacaagtgg ttgtaattga
     2701 tatgagacat gctcatttct ctccctgata acaatgaaaa gggagccgtt tatggctccc
     2761 cggtaaaccg tcctgtcaaa ctgatggacg caaacgaacg cgtaaccagc tgtatccaat
     2821 taccgccgaa gagatagaac cgaccaggat accgagtttc gcccagttaa tcagttctgg
     2881 atctacgtta ccaaaggcca ggctggcaat aaagatagac atagtaaaac cgataccgca
     2941 caggatcccc accgccataa tttgctgata agtcgttccc tcaggcagat gcgccagttt
     3001 caaacgcagc gccaaccagc agaacagact aatccccagc ggtttgccaa tcagcaagcc
     3061 agcgatgatc cccaatggca gaatggaggt caagccatcc aacgtgacac cttgcagtga
     3121 aacgccagca ttagcaaatg caaacagcgg caaaatcaga tacgccaccc acgggtgtaa
     3181 cacatgctcc agtcgcttcg ctggagaacg cccatgcttc tctttcaaag gaataaagaa
     3241 gccgacaatt acccccgcca gggttgcgtg aacccccgat ttcaacaccg cagtccacaa
     3301 cactacgcca accagaatat agacgcccgt gcggcgtaca ccacacagat tcaataccgc
     3361 gagtaccgca attgctacag ccgcgacgcc aagagaggcc atcgataagt cattagtgta
     3421 gaacaatgcg atgataatga tggccccaag atcgtcgata atagccagag ccatcaaaaa
     3481 gatcttcagc gctaacggaa cacgacttcc caacagcgcc agcacaccaa gtgcaaaggc
     3541 aatgtcagta gccgccggga tcgcccaccc ttcgcgggta atcggatcgg catagttaaa
     3601 ggccagatag agtaatgccg gaacaatcat cccaccaata gcggcgataa ctggaaatgc
     3661 ggcctggcgt aagctggcta gcgatccttg catcagttca cgtttaactt ccagaccgac
     3721 taacaggaaa aataccgcca tcagcgcgtc atttatccat aacagcatgt ttttgttgat
     3781 ttcgagtgaa ccaacccgga gctgaaccgg cgtctccaga aagtcgtgat accatccact
     3841 ggttgcgccg ctattggcca taatcatcgc caggatagcg gcaatgataa gaataatgcc
     3901 tcccgaggca tcactgctaa agaatcgatg cagatgtttc actttttatt tctctttcag
     3961 gtgaatagat cgtttttact attttacccc gcacaaatca tcgttaaaat cagattatag
     4021 tgtaggaata actcgttttt tacgatccat tgaagaattt gcgccatcag cggtgagatg
     4081 agtttttgac ggctgtaagc gctcacgagt gaccctaagc ccagataatc atagcttaag
     4141 gtgaggattt ctgagggatt aattaggaaa agtaataatt aatttcttgt cagtcggcgt
     4201 tatttgttag gacaatattt caaaaataat ccagcttgtc gtcaataatt gcgataaaga
     4261 gataaattaa agttaaataa ttaaatcatt aaaaaattac gccacaaaaa tgcgaggcgt
     4321 cttcaggatt agaatcgata aaacagaatg ggttaaagag agcgatctaa tagcgacggg
     4381 tgcttgaggc tatctgtctc aggcattagc tgaacggcag atagagaaaa gccccgagtg
     4441 atattttact atcaacccga ggccccctat atgctgaaca catgtagagt gcctcttact
     4501 gaccataagg tcaaggagaa gagagcaatg aagcagcata aggcgatgat tgtcgccctg
     4561 atcgtcatct gtatcaccgc cgtagtggcg gtgctggtaa cgagaaaaga cctctgtgag
     4621 gttcacatcc gaactggcca gacggaggtt gctgttttca cggcttacga atccgagtaa
     4681 gagcaacggc ggggagtgat ccccgccact tttcaggtgc tcgcatatct tcaacgcacc
     4741 ctaattttac ccaagcctgc ccacgggcag gcttttgggg aggttagcgg gtcaggtcgt
     4801 caaaaaactt cttcacacca tcaaagaagc tctttgagcg cgggctgttg tgctcaccgg
     4861 ttgggccacc gaagctttct tgcagctctt gcagcagctg tttctgcttc tcgttcaggc
     4921 ctaccggtgt ttcgacgaca acgcggcaca gtaaatcacc ctgtgcgcca ccgcggacag
     4981 acttgacgcc tttaccgcgc atacggaaca gcttaccagt ctgggtttcg ccaggcactt
     5041 tcagtttgac gcgaccatca agggtcggta cttcgatttc gccacccagc gccgccatag
     5101 cgaagttgat cgggacttcg caatacaggt tgttgccttc acgctcgaaa atcgggtgct
     5161 gtttaacctg aacctgaacg tacagatcgc ctgccggtgc gccatgctcg cccgcttcac
     5221 cttcgcccgc aagacggatg cggtctccag tgtccacccc tgccgggatt ttaacggaca
     5281 gcgttttgct gcgctcaaca cgaccatgac catgacattt gttgcacgga tctttgatca
     5341 gcgtaccgcg gccctgacag tgtggacagg tctgctgcac ggcaaagaaa ccctgacgca
     5401 tctgcacctg accagaacca tgacaggtcg gacaggtctg cggctgtgta cctggttttg
     5461 caccgctacc gtggcaaacg tcacactctt ccagagtcgg aatgcggatc tctttggtca
     5521 cgccacgtac agcttcttcg agggtgagct ccatgttata gcgtaaatca gcaccgcgcg
     5581 ccgcacgttg acgaccacgt ccgccgccaa aaatatcgcc gaaaacgtca ccaaaaatat
     5641 cgctgaagtc tgcgccgccg ccaaaaccgc cgccgcccat gccgccttgc tcaaacgcag
     5701 catgaccata ctgatcgtat gccgcacgtt tttgcgagtc ggtcagaact tcataagctt
     5761 ccttgatctc tttaaatttc gcctcggcct ctttgtcacc ctggttacgg tccgggtggt
     5821 atttcatggc caggcgtttg taggcctttt tgatttcacg ctcttccgct gttttggaaa
     5881 cgcctaaaat ctcgtaataa tcttgcttag ccatcttttt taaattgccc ctagatgaat
     5941 gcacgggcgg agaggaaatt ccccttcgcc cgtgtcagta taattacccg tttatagggc
     6001 gattattttt tgtctttgac ttcttcaaat tcagcgtcga caacatcgtc atctttcgcg
     6061 ttgtttgcag aagcatcagc accggcagtc tgctgctggg catgttgctg ctgggcgatt
     6121 tccatcagtt tctgggaaac ctgtgccagc tcctgcattt tcgcttcgat agcggctttg
     6181 tcttcacctt tcagagcagt ttccagtgca gtcagtgcag actcgatagc agttttgtcg
     6241 tcagccggca gtttgtcgcc tgcttcttca acctgcttac gggtgctgtg cagcagatgg
     6301 tcgccctggt tgcgagtctg taccagctct tcaaacttac ggtcagcttc ggcgttagct
     6361 tctgcgtcgc gtaccatttt ctggatttca tcttcgttca gaccagaaga cgccttgatg
     6421 gtgatcttct gctctttacc gctgttttta tctttcgcgg aaacgtgcag gataccgtca
     6481 gcatcgatat cgaaggtaac ttcgatctgc ggcatgccgc gcggtgccgg gttgatacca
     6541 tccaggttga actgacccag agatttgtta tcagccgcac gtttacgttc accctgcagc
     6601 acatggatgg ttaccgcaga ctggttgtct tcagcggtag agaacacctg gctgtgcttg
     6661 gtcgggatag tggtgttttt cgcgatcagc gtcgtcatca caccgcccat ggtttcgata
     6721 cccagagaca gcggggtaac gtccagcagc agtacgtctt tcacgtcacc agtcagaaca
     6781 ccaccctgaa cagcagcacc gattgctaca gcttcgtccg ggttaacgtc tttacgcggc
     6841 tctttaccaa agaactcagc aactttcttc tgaaccattg gcatacgagt ctgaccacca
     6901 acgaggataa cgtcgtcgat atcagatacg gacaggccag cgtcctgcag tgcaactttc
     6961 agcggctcaa tggaacggtt taccagatct tcaaccaggc tttccagttt cgcacgagtc
     7021 actttgatgt tcatgtgttt cggaccggtc gcatctgcag tgatgtacgg caggttaacg
     7081 tcggtctgct gagcggaaga cagttcgatt ttcgcttttt ctgccgcttc tttcaggcgc
     7141 tgcattgcca gcggatcgtt gcgcaggtca atgccctgat ctttcttgaa ttcttcaacc
     7201 aggtagttga tcagacggct gtcgaagtct tcaccaccca ggtgggtatc accgttggta
     7261 gccagaactt cgaaggtttt ttcgccgtca acttcgtcga tttcgataat agaaatatcg
     7321 aaagtaccac cacccaggtc ataaaccgcg atagtacggt tgccagtacc tttgtccaga
     7381 ccgtaagcca gcgcagctgc ggtcggttcg ttgatgatac gttttacttc cagaccagcg
     7441 atacggcctg cgtctttggt tgcctgacgc tgagcatcgt taaagtatgc cggtacggtg
     7501 ataacagctt cagttaccgg ttcacccaag taatcttcag cggttttctt catttttttc
     7561 agcacttcag cagaaatctg cggcggtgcc attttctggc ctttaacttc gacccatgcg
     7621 tcgccgttat cagcagcaat aattttgaac ggcatgatgg aaacatcacg ctgtacttct
     7681 tcgtcctgga agcggcggcc aatcaggcgt ttaatcgcaa acagggtgtt ttgcgggttt
     7741 gtcactgcct gacgtttagc cggctgacca accagagttt caccatcctg ggtataggca
     7801 ataatagaag gcgtggtgcg atcgccttcg gcgttctcca gcacgcgagg agtggtgcca
     7861 tccataatcg ctacacaaga gttggtagta cccaggtcga taccaattat tttacccatc
     7921 taaacgtctc cactatatat tcggtcatca tgtggttgtg agtctgtaat aggggcgaaa
     7981 cgtctggttt caactgccca atttcatttt tttgcagact cactcactgc ggttgactac
     8041 taaatggggt cgtaacccac gtcatcaagg gggagatgca aaaatttttt gtgcttttgc
     8101 gcagaaattt cgcgatatgg caggacaaga cgtaaaattg acagcaattt tattcatata
     8161 aagaatgaat cgcagccaag gcattcatca aaaaattgta ataaaaagaa aagattacgt
     8221 acctgaatct tctctttatc agcagtaaac tagtgggtat tcatccctct acctcttccc
     8281 actaagagaa tccttatgaa atccgttttt acgatttccg ccagcctggc gattagcctg
     8341 atgctgtgct gcacggcgca ggcaaacgac cataaactcc tcggcgtcat tgcaatgccg
     8401 cgtaacgaaa ccaacgatct ggcgctgaaa cttcctgttt gtcgcattgt gaaacgcata
     8461 caactctctg ccgaccatgg cgatttacag ttaagcgatg catcggttta tttcaaagcc
     8521 gcccgtagcg ccagtcagag tctgaatatt ccttcagaaa taaaagaagg gcaaaccact
     8581 gactggatca acattaacag tgataacgac aataaacgct gcgtctcaaa aatcaccttt
     8641 tccggtcata cggtgaactc atcggatatg gccacgctga aaattatcgg cgacgactaa
     8701 cgccagaata tagaaaccac aaaaaatgaa tgttaattac ctgaatgatt cagatctgga
     8761 ttttcttcag cattgtagtg aggaacagtt ggcaaatttc gcccgattgc tcacccataa
     8821 tgaaaaaggc aaaactcgcc tctccagcgt actgatgcgc aacgaactgt ttaaatcgat
     8881 ggaagggcat cccgagcaac atcgccgcaa ctggcagctg attgctggag aattacagca
     8941 ttttggtggc gatagtatcg ccaacaaact gcgcggacac ggtaaattgt atcgggccat
     9001 tttgctcgat gtttcaaaac gattgaagct gaaagccgac aaagagatgt ctacgtttga
     9061 gattgagcaa cagttactgg aacaatttct gcgtaacacc tggaagaata tggacgagga
     9121 acataagcag gagtttctgc acgcggtcga tgccagggtg aataagctgg aagagctgct
     9181 gccgctgctg atgaaagaca aattattggc aaaaggcgtg tcgcatttgc tttccagcca
     9241 attgacccgc attttacgca cccacgcagc aatgagcgtg cttgggcatg gtttgctgcg
     9301 cggcgcgggt ctgggaggcc ctgtgggcgc agcattaaat ggggttaaag cggtcagcgg
     9361 cagtgcctat cgcgtgacaa ttccagccgt actgcaaatc gcctgcctgc gccggatggt
     9421 tagcgccact caggtctgac accgtaaacc ggggaaaatt ttcattttcc cctcaaaaga
     9481 tcgtagacac tgccccactg gctgattatt atgccgcgcc ctgaaaacac tacagttatt
     9541 cagggaaatt atttcaccat tcattcgatg atgatttttg aggaattatg ggcaacacta
     9601 agttggctaa tccggcaccg ctgggcctga tgggcttcgg catgaccacc attctgctta
     9661 acctgcacaa cgtgggttat ttcgctctgg acggtattat tcttgccatg ggcattttct
     9721 acggcggcat cgcgcaaatt tttgccggtc tgctggagta caaaaaaggc aacactttcg
     9781 gtttaaccgc attcacctct tacggttctt tctggctgac gctggttgcg attctgctga
     9841 tgccgaaact gggtctgacc gatgcgccaa atgcacagtt ccttggtgtc tacctgggtc
     9901 tgtggggcgt atttacgctg tttatgttct tcggcacgct gaaaggcgca cgcgttctgc
     9961 aattcgtttt ctttagcctg accgtgctgt ttgccctgct ggcgatcggt aacattgccg
    10021 gtaacgccgc aatcatccac tttgccggct ggattggtct gatctgcggt gccagcgcaa
    10081 tctatctggc gatgggtgaa gtactgaacg agcagtttgg tcgcaccgtt ctgccgattg
    10141 gtgaatccca ctaattgttt tgagatcccc ccgctcgggg ggattttttt attcgctaac
    10201 gtcgcgtctt gcactcttcg gtctgaatgc agcaaccact tctggtgccg tttcaacgta
    10261 tggcccttcc agcaactgaa tgcagtacgg tacgctggca aaaataccgt gtaccacaac
    10321 gttaccctca gcgtccttca caccttccag cgtctcttta atagacttcg gctgaccggg
    10381 taagttaagg atcagcgcct gtttgcgaat cacgcccacc tgacgcgaaa ggatcgcagt
    10441 tggtacaaaa tgcaggctga tctggcgcat ctgttcacca aagccaggca tctcgcggtc
    10501 cgctactgcc agcgtcgcat cgggcgttac gtcacgacgc gccgggccag ttccgcccgt
    10561 ggtgagcacc agatggcaac tcatttcatc cactagctca cacaacgttt gctcgatgat
    10621 cgcctgctca tcggggatta agcgggtttc cagttcaaac ggcgtggtta gcgccgatgt
    10681 cagccattct tccagcgcag ggatgccttt atcctgataa acgccgctgg atgcgcgatc
    10741 agagatggaa actaagccaa tacgtaaagt attcatcaag atttttccgt ttaaacagtc
    10801 tcgttaaaca gaatgataca ctgcgaaggg agtgacagac aggcttcaga agaggtagcg
    10861 tgaccgactt cccggtcacg ctaagaatga ttacagcaga tcgccgatca ttttttccag
    10921 tttttcctgg tcaatagcaa acttacggat accttccgcc agtttatcta ctgccattgg
    10981 atcctggttg tgctgccaca ggaactcgga ctcagtgata cgcgccggac gcgctttcac
    11041 ttcgccggtg taagacagtt tacgttcgat agccccttcg ctctccgcca gctctttcag
    11101 cagtgccggt gcgatggtca gacggtcgca gcctgccagt tccagaattt cgccgatgtt
    11161 acggaagctt gcgcccataa ccactgtttc ataaccgtgc tctttgtagt actggtagat
    11221 ttcagataca gaaaccacgc ccggatcttc tgccggagcg tactctttct tatcagtatt
    11281 cgctttgtac cagtcaagaa tacggccaac aaatggcgag atcaggaaca cgcctgcttc
    11341 cgcacaagca cgagcctgag cgaaggagaa cagcagggtc aggttacagt tgatgccttc
    11401 tttttccagc tgttctgcag cacggatacc ctgccaggta gaagccagtt tgatcagaat
    11461 acgatcgttg ctaataccag catcgttgta gagtttgatc aggcgttttg ctttcgcaat
    11521 tgacgcttcg gtgtcatagg aaagacgcgc atcaacttca gttgagatac ggcccggaac
    11581 cagtttcagg atttccagac caatatttac tgccagtttg tcggtcgcgt ccacgatctg
    11641 ctgcgcgcga tcgttgctct gctgtttcgc ccaagcgaca gcatcatcaa tcaacttacg
    11701 gtattccgga atctgcgctg cgttaagaat gagagaaggg ttggttgtgg catcctgcgg
    11761 ttgatacagc ttcattgccg cgatgtcccc agtgtcggcc actacggtgg tgtactgacg
    11821 aagggaggtc aatttgtccg tcatgatagt atttctcttt aaacagcttg ttagggggat
    11881 gtaaccggtc tgccctgatg atatcacgac gcaacgtcag cgcaaccgcc gacaagacgg
    11941 ttatcgccag gcgagactgt ttcggatttc tgacactgcg ttgatatcgc ccgccatttt
    12001 tatacaaaac ctcatgtatg ctacgcagaa gttatcaagt acctcgtagc gtatatactt
    12061 cttaaacaat tggtaacgtt tacacaggaa agtcatcgcg accggcaata agagggatat
    12121 gcatgccaga ttttttctcc tttattaaca gcgtcctttg gggatcggta atgatttacc
    12181 tgctcttcgg cgcaggttgt tggttcactt ttcgcaccgg atttgtgcag tttcgctaca
    12241 tccgccagtt tggcaaaagt cttaaaaata gcattcatcc acagccaggc ggtttaacct
    12301 catttcagtc attgtgtacc agtcttgcgg cgcgcgtggg tagcggcaac ctggccggcg
    12361 ttgcgctggc tattaccgcc ggtggacctg gagccgtctt ttggatgtgg gttgccgcgt
    12421 ttatcggcat ggcgacctcg tttgccgaat gttcccttgc acaactttat aaagaacgtg
    12481 acgtcaatgg acagtttcgt ggaggaccgg catggtatat ggcgcgcggg ctggggatgc
    12541 gttggatggg cgttctgttc gccgtctttt tgctcatcgc ctacggcata attttcagcg
    12601 gagttcaggc gaacgccgtt gcccgagccc tgagtttttc ttttgatttt cccccgctgg
    12661 tgacaggcat tattctcgct gtctttgctc tgctggcaat cactcgcggt cttcatggcg
    12721 tcgcccggct catgcagggg tttgtcccgt tgatggcgat aatctgggtg ctgaccagca
    12781 tggtgatttg cgtaataaat atcgggcaac ttccccacgt catttggtct atttttgaga
    12841 gtgcttttgg ctggcaggaa gcggcaggcg gcgcggcggg atatacctta agccaggcga
    12901 ttactaacgg ttttcagcgc agtatgtttt ccaatgaggc gggaatgggt tcgacgccaa
    12961 acgcggcagc ggcagcggcg tcctggcctc cgcatccggc agcgcaaggg attgtccaga
    13021 tgattggcat ttttatcgac accctggtca tctgtacggc aagcgccatg ctgatattac
    13081 tggcgggtaa cgacacaacc tacatgccgc tggaaggtat tcagcttatc cagaaggcga
    13141 tgcgggtgct aatgggttcc tggggtgctg agtttgttac cctcgtggtt attctgtttg
    13201 ccttcagctc catcgttgcc aactacattt atgccgaaaa caatctcttc tttttacgcc
    13261 tgaacaaccc taaagcgatc tggtgtttgc ggatctgcac cttcgcaacg gtcatcggcg
    13321 gcaccttgct aagccttccg ctgatgtggc aactggcaga tatcataatg gcctgcatgg
    13381 ctattaccaa tttgaccgcc attttactgc tctcgcctgt ggttcatacc attgccagtg
    13441 attatctacg ccagcgtaaa ctcggcgtgc gcccggtgtt tgatccgttg cgttatccgg
    13501 atatcggtcg ccagctttct ccggacgcgt gggatgatgt ttcgcaggag taatcacaac
    13561 tatcgatcaa ctcattctct ttttttgcta aagtcggcat aaatttcctg caaggactgg
    13621 atatgctgat tcttatttca cctgcgaaaa cgcttgatta ccaaagcccg ttgaccacca
    13681 cgcgctatac gctgccggag ctgttagaca attcccagca gttgatccat gaagcgcgga
    13741 aactgacgcc tccgcagatt agcacgctga tgcgcatcag cgacaaactg gcgggtatca
    13801 acgccgctcg ctttcatgac tggcagccag atttcacgcc ggagaatgcc cgccaggcga
    13861 ttctggcgtt taaaggtgat gtctacaccg gcttgcaggc cgaaaccttc agcgaagacg
    13921 atttcgattt tgcccaacag catttgcgaa tgctttccgg cttgtatggc gtactgcgcc
    13981 cgctagattt aatgcagcct tatcgtctgg aaatggggat ccgtcttgag aatgcccgag
    14041 ggaaagatct gtatcaattc tggggagata tcatcaccaa caagctgaac gaggcgctcg
    14101 cagcacaagg cgataatgtg gtgattaatc tggcgtcaga tgagtatttt aaatcggtga
    14161 agccgaagaa attgaatgcc gagattatca agccggtgtt cctcgatgag aagaacggca
    14221 aatttaagat catcagcttc tacgctaaga aagcacgcgg tctgatgagt cgtttcatta
    14281 ttgaaaatcg gctgaccaaa ccagagcaac tgactggttt taataccgaa ggttacttct
    14341 ttgatgaagc ttcctccagc aatggtgaac tggtgtttaa acgctacgag cagcgttaag
    14401 tttgtagcca atgccggatg cggcgtgaac gccttatccg gcctacaaaa gcatgcagat
    14461 tcaatatatt gcagaatta
//
LOCUS       DADXDL010000110        14142 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.110, whole genome shotgun sequence.
ACCESSION   DADXDL010000110 DADXDL010000000
VERSION     DADXDL010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 14142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14142
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.110"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..400)
                     /gene="tnpA"
                     /locus_tag="IRB70_004108"
     CDS             complement(<1..400)
                     /gene="tnpA"
                     /locus_tag="IRB70_004108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBC0633954.1"
                     /translation="MKKETDIRRGRHCVFLKHVHLVFVTKYRRQIFDHDATEKLRTYF
                     SNVCADFEAERVEMDGGPDHVHLLINYPPKLAISSLVNSLKGVSSRLLRRDRPDIAVR
                     YYDKGVLWSPGYFVSSCILTYQLDLITTISV"
     gene            423..752
                     /locus_tag="IRB70_004109"
     CDS             423..752
                     /locus_tag="IRB70_004109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001324015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0633955.1"
                     /translation="MKRLQAFKFRLRPGGQQEREMRRFAGACRFVFNRALALQNENHE
                     AGNKYIPYGKMASWLVEWKNATETQWLKDSPSQPLQQSLKDPERAYKNFFRLRHHAQT
                     VCYLSRL"
     gene            complement(634..1131)
                     /locus_tag="IRB70_004110"
     CDS             complement(634..1131)
                     /locus_tag="IRB70_004110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000334561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBC0633956.1"
                     /translation="MCGRFAQSQTREDYLALLAEDIERDIPYDPEPIGRYNVAPGTKV
                     LLLSERDEHLHLDPVFWGYAPGWWDKPPLINARVETAATSHMFKPLWQHGRAICFADG
                     WFEWKKEGDKKQPYFIYRADGQAVFIAAIGSTPFERGDEAGRSFCKPAQGLSVTVAMA
                     VRANL"
     gene            complement(1240..1473)
                     /gene="yedF"
                     /locus_tag="IRB70_004111"
     CDS             complement(1240..1473)
                     /gene="yedF"
                     /locus_tag="IRB70_004111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310696.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfurtransferase-like selenium metabolism
                     protein YedF"
                     /protein_id="HBC0633957.1"
                     /translation="MKNIVPDYRLDMVGEPCPYPAVATLEAMPQLKKGEILEVVSDCP
                     QSINNIPLDARNHGYTVLDIQQDGPTIRYLIQK"
     gene            complement(1470..2675)
                     /gene="yedE"
                     /locus_tag="IRB70_004112"
     CDS             complement(1470..2675)
                     /gene="yedE"
                     /locus_tag="IRB70_004112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenium metabolism membrane protein YedE/FdhT"
                     /protein_id="HBC0633958.1"
                     /translation="MSWQQFKHAWLIKFWAPIPAVIAAGILSTYYFGITGTFWAVTGE
                     FTRWGGQLLQLFGVHAEEWGYFKIIHLEGSPLTRIDGMMILGMFGGCFAAALWANNVK
                     LRMPRSRIRIMQAIIGGIIAGFGARLAMGCNLAAFFTGIPQFSLHAWFFAIATAIGSW
                     FGARFTLLPIFRIPVKMQKVSAASPLTQKPDQARRRFRLGMLVFFGLLGWALLTAMNQ
                     PKLGLAMLFGVGFGLLIERAQICFTSAFRDMWITGRTHMAKAIIIGMAVSAIGIFSYV
                     QLGVEPKIMWAGPNAVIGGLLFGFGIVLAGGCETGWMYRAVEGQVHYWWVGLGNVIGS
                     TILAYYWDDFAPALATDWDKINLLKTFGPMGGLLVTYLLLFAALMLIIGWEKRFFRRA
                     APQTAKEIA"
     gene            2862..3275
                     /locus_tag="IRB70_004113"
     CDS             2862..3275
                     /locus_tag="IRB70_004113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310694.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBC0633959.1"
                     /translation="MKKLAIAGALMLLAGCAEVENYNNVVKTPAPDWLAGYWQTKGPQ
                     RALVSPEAIGSLIVTKEGDTLDCRQWQRVIAVPGKLTLMSDDLTNVTVKRELYEVERD
                     GNTIEYDGMTMERVDRPTAECAAALDKAPLPTPLP"
     gene            complement(3309..4796)
                     /gene="amyA"
                     /locus_tag="IRB70_004114"
     CDS             complement(3309..4796)
                     /gene="amyA"
                     /locus_tag="IRB70_004114"
                     /EC_number="3.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-amylase"
                     /protein_id="HBC0633960.1"
                     /translation="MRNPTLLQCFHWYYPEGGKLWPELAERADGFNDIGINMVWLPPA
                     YKGASGGYSVGYDSYDLFDLGEFDQKGSIPTKYGDKAQLLAAIDALKRNDIAVLLDVV
                     VNHKMGADEKEAIRVQRVNADDRTQIDEEIIECEGWTRYTFPARAGQYSQFIWDFKCF
                     SGIDHIENPDEDGIFKIVNDYTGEGWNDQVDDELGNFDYLMGENIDFRNHAVTEEIKY
                     WARWVMEQTQCDGFRLDAVKHIPAWFYKEWIEHVQEVAPKPLFIVAEYWSHEVDKLQT
                     YIDQVEGKTMLFDAPLQMKFHEASRMGRDYDMTQIFTGTLVEADPFHAVTLVANHDTQ
                     PLQALEAPVEPWFKPLAYALILLRENGVPSVFYPDLYGAHYEDVGGDGQTYPIDMPII
                     EQLDELILARQRFAHGVQTLFFDHPNCIAFSRSGTDEYPGCVVVMSNGDDGEKTIHLG
                     ENYGNKTWRDFLGNRQESVVTDENGEATFFCNGGSVSVWVIEEVI"
     gene            complement(4874..5239)
                     /gene="fliT"
                     /locus_tag="IRB70_004115"
     CDS             complement(4874..5239)
                     /gene="fliT"
                     /locus_tag="IRB70_004115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliT"
                     /protein_id="HBC0633961.1"
                     /translation="MNNAPHLYFAWQQLVEKSQLMLRLATEEQWDELIASEMAYVNAV
                     QEIAHLTEEVAPSTTMQEQLRPMLRLILDNESKVKQLLQIRMDELAKLVGQSSVQKSV
                     LSAYGDQGGFVLAPQDNLF"
     gene            complement(5239..5649)
                     /gene="fliS"
                     /locus_tag="IRB70_004116"
     CDS             complement(5239..5649)
                     /gene="fliS"
                     /locus_tag="IRB70_004116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar export chaperone FliS"
                     /protein_id="HBC0633962.1"
                     /translation="MYAAKGTQAYAQIGVESAVMSASQQQLVTMLFDGVLSALVRARL
                     FMQDNNQQGKGVSLSKAINIIENGLRVSLDEESKDELTQNLIALYSYMVRRLLQANLR
                     NDVSAVEEVEALMRNIADAWKESLLSPSLIQDPV"
     gene            complement(5665..7080)
                     /gene="fliD"
                     /locus_tag="IRB70_004117"
     CDS             complement(5665..7080)
                     /gene="fliD"
                     /locus_tag="IRB70_004117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar filament capping protein FliD"
                     /protein_id="HBC0633963.1"
                     /translation="MASISTLGVGSGLDLSSILDSLEAAEKSTLTPISKQQSSYTAKL
                     SAYGTLKSALESFQTANTALNKADLFTATSTTSSSSAFSATTTGSAIAGKYTISVSQL
                     AQAQTLTTKNSQKDSKAAIATSDSVLTIQQGGGKDPVTIDISAGNSSLSGIRDAINNA
                     KAGVSASIINVGNGEYRLSITANDTGSNNAMKLSVSGDSALESFMGYNGTPGDSSNGM
                     IESVTAQNAKLTVNNVEIENSSNTISDSLEDITLNLNDVTTGNQTLTISKDTSKAENA
                     VKAWVDAYNTLQDTFSSLTKYTAVDAGAESQDSSNGALLGDSTLRTIQTQLKTLLANT
                     HSSSNYKTLAQIGITSDASTGKLEIATDKLQTALKNDAAGIGEMFIGDGKSTGVTTGI
                     SNNLTSWLSSTGIIQAAKDGVSKTLNNLTDQYNAASERIDTLMTRYKAQFTQLDVLMN
                     SLNSTSSYLTQQFDTSNSNSK"
     gene            7328..8374
                     /locus_tag="IRB70_004118"
     CDS             7328..8374
                     /locus_tag="IRB70_004118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000079755.1"
                     /note="structural flagella protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellin FliC"
                     /protein_id="HBC0633964.1"
                     /translation="MAQVINTNSLSLITQNNINKNQSALSTSIERLSSGLRINSAKDD
                     AAGQAIANRFTSNIKGLTQAARNANDGISLAQTAEGALSEINNNLQRIRELTVQASTG
                     TNSDSDLSSIQDEIKSRLDEIDRVSGQTQFNGVNVLSKNDSMKIQIGANDNQTISIGL
                     QQIDSTTLNLKGFTVSGMADFSAAKLTAADGTAIAAADVKDAGGKQVNLLSYTDTASN
                     STKYAVVDSATGKYMEATVAITGTAAVTVGAAEVAGAATADPLKALDAAIAKVDKFRS
                     SLGAVQNRLDSAVTNLNNTTTNLSEAQSRIQDADYATEVSNMSKAQIIQQAGNSVLSK
                     ANQVPQQVLSLLQG"
     gene            8538..9257
                     /gene="fliA"
                     /locus_tag="IRB70_004119"
     CDS             8538..9257
                     /gene="fliA"
                     /locus_tag="IRB70_004119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor FliA"
                     /protein_id="HBC0633965.1"
                     /translation="MNSLYTAEGVMDKHSLWQRYVPLVRHEALRLQVRLPASVELDDL
                     LQAGGIGLLNAVERYDALQGTAFTTYAVQRIRGAMLDELRSRDWVPRSVRRNAREVAQ
                     AIGQLEQELGRNATETEVAERLGIDIADYRQMLLDTNNSQLFSYDEWREEHGDSIELV
                     TDDHQRENPLQQLLDSNLRQRVMEAIETLPEREKLVLTLYYQEELNLKEIGAVLEVGE
                     SRVSQLHSQAIKRLRTKLGKL"
     gene            9303..9854
                     /gene="fliZ"
                     /locus_tag="IRB70_004120"
     CDS             9303..9854
                     /gene="fliZ"
                     /locus_tag="IRB70_004120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310687.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagella biosynthesis regulatory protein FliZ"
                     /protein_id="HBC0633966.1"
                     /translation="MMVQHLKRRPLSRYLKDFKHSQTYCAHCRKLLDRITLVRDGKIV
                     NKIEISLLDALLDENGWQTEQKSWAALCRFCGDLHCKTQSDFFDIIGFKQFLFEQTEM
                     SPGTVREYVVRLRRLGNHLHEQNISLDQLQDGFLDEILAPWLPTTSTNNYRIALRKYQ
                     HYQRQTCTGLVQKSSSLPASDIY"
     gene            9942..10742
                     /gene="tcyJ"
                     /locus_tag="IRB70_004121"
     CDS             9942..10742
                     /gene="tcyJ"
                     /locus_tag="IRB70_004121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter substrate-binding
                     protein"
                     /protein_id="HBC0633967.1"
                     /translation="MKLAHLGRQALMSVMAVALVAGMSVKSFADEGLLNKVKERGTLL
                     VGLEGTYPPFSFQGDDGKLTGFEVEFAQQLAKHLGVEASLKPTKWDGMLASLDSKRID
                     VVINQVTISDERKKKYDFSTPYTISGIQALVKKGNEGTLKTAADLKGKKVGVGLGTNY
                     EEWLRQNVQGVDVRTYDDDPTKYQDLRVGRIDAILVDRLAALDLVKKTNDTLAVTGEA
                     FSRQESGVALRKGNEDLLKAVNDAIAEMQKDGTLQALSEKWFGADVTK"
     gene            10847..11833
                     /gene="dcyD"
                     /locus_tag="IRB70_004122"
     CDS             10847..11833
                     /gene="dcyD"
                     /locus_tag="IRB70_004122"
                     /EC_number="4.4.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416429.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-cysteine desulfhydrase"
                     /protein_id="HBC0633968.1"
                     /translation="MPLHNLTRFPRLEFIGAPTPLEYLPRFSDYLGREIFIKRDDVTP
                     MAMGGNKLRKLEFLAADALREGADTLITAGAIQSNHVRQTAAVAAKLGLHCVALLENP
                     IGTTAENYLTNGNRLLLDLFNTQIEMCDALTDPNAQLEELATRVEAQGFRPYVIPVGG
                     SNALGALGYVESALEIAQQCEGAVNISSVVVASGSAGTHAGLAVGLEHLLPESELIGV
                     TVSRSVADQLPKVVNLQQAIAKELELTASAEILLWDDYFAPGYGVPNDEGMEAVKLLA
                     RLEGILLDPVYTGKAMAGLIDGISQKRFKDEGPILFIHTGGAPALFAYHPHV"
     gene            11848..12516
                     /gene="tcyL"
                     /locus_tag="IRB70_004123"
     CDS             11848..12516
                     /gene="tcyL"
                     /locus_tag="IRB70_004123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystine ABC transporter permease"
                     /protein_id="HBC0633969.1"
                     /translation="MQESIQLVIDSLPFLLKGAGYTLQLSIGGMFFGLLLGFILALMR
                     LSPIWPVRWLARFYISIFRGTPLIAQLFMIYYGLPQFGIELDPIPSAMIGLSLNTAAY
                     AAETLRAAISSIDKGQWEAAASIGMTPWQTMRRAILPQAARVALPPLSNSFISLVKDT
                     SLAATIQVPELFRQAQLITSRTLEVFTMYLAASLIYWIMATVLSTLQNHFENQLNRQE
                     REPK"
     gene            12513..13265
                     /gene="yecC"
                     /locus_tag="IRB70_004124"
     CDS             12513..13265
                     /gene="yecC"
                     /locus_tag="IRB70_004124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine ABC transporter ATP-binding protein
                     YecC"
                     /protein_id="HBC0633970.1"
                     /translation="MSAIEVKNLVKKFHGQTVLHGIDLEVKPGEVVAIIGPSGSGKTT
                     LLRSVNLLEQPEAGTITVGDITIDTARSLSQQKSLIRQLRQHVGFVFQNFNLFPHRTV
                     LENIIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARALA
                     MRPEVILFDEPTSALDPELVGEVLNTIRQLAQEKRTMVIVTHEMSFARDVADRAIFMD
                     QGRIVEQGAAKALFADPQQPRTRQFLEKFLLQ"
     gene            13495..14142
                     /gene="sdiA"
                     /locus_tag="IRB70_004125"
                     /pseudo
     CDS             13495..14142
                     /gene="sdiA"
                     /locus_tag="IRB70_004125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310681.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator SdiA"
BASE COUNT         3522 a         3494 c         3637 g         3489 t
ORIGIN      
        1 gtacggatat cgttgttatt aaatctagtt gatacgttaa gatgcagcta ctgacaaaat
       61 agccaggact ccacaaaacg cctttgtcgt aatacctgac tgcaatatct ggtcgatctc
      121 gtcgcagtaa cctactcgat acgcctttga ggctgtttac cagactggat atcgccagtt
      181 tgggaggata gttaattaac aaatggacgt gatctggtcc gccatccatt tcaacccgtt
      241 cagcttcaaa atcagcacat acatttgaaa agtaagtgcg tagtttttct gtcgcgtcat
      301 ggtcaaaaat ctgacgtcgg tatttagtaa cgaagactag gtgaacatgc ttcaggaaaa
      361 cacaatgcct tccgcgtcgg atatcggttt cttttttcat aggccaaagt atgatttggc
      421 ccatgaaacg actacaggca ttcaaattcc ggttaagacc aggtggtcaa caggagcgtg
      481 aaatgaggcg cttcgcaggc gcatgtcgtt tcgttttcaa tcgtgctctg gcgcttcaga
      541 atgagaatca tgaggccggt aataaataca tcccttacgg gaaaatggct tcctggttgg
      601 ttgagtggaa aaatgccact gaaacgcaat ggcttaaaga ttcgccctca cagccattgc
      661 aacagtcact gaaagaccct gagcgggctt acaaaaactt cttccggctt cgtcaccacg
      721 ctcaaacggt gtgctaccta tcgcggctat aaaaacagct tgtccatcag cacgatagat
      781 aaaataaggc tgctttttgt cgccttcttt tttccactca aaccagccat cggcaaaaca
      841 gattgcccga ccatgttgcc agagcggttt aaacatgtga ctggttgcgg cagtttctac
      901 gcgggcgtta atcagcggcg gtttatccca ccatccggga gcatatcccc agaaaaccgg
      961 atccagatga aggtgttcat cacgttcact gagcagaagg actttggttc ccggcgcgac
     1021 gttgtatctg ccaataggtt cgggatcgta gggaatatcg cgttcaatat cttccgcgag
     1081 aagcgcaagg taatcttcac gcgtttggga ttgggcaaag cgtccacaca tagaaacctc
     1141 ctgaggtcac actgaaaaga ataggagagg gggcgggtta aatctatgtg atagagaggc
     1201 aacgatattc ccgctgtggg ccacagcggg aatgagggat tacttctgaa ttaaataacg
     1261 aatggtcggc ccgtcttgct gaatatccag caccgtatag ccgtgattac gcgcatccag
     1321 tggaatatta ttgatcgact gcggacagtc gctcaccact tccaggatct cccctttttt
     1381 taactgcggc atcgcctcaa gggttgcgac tgccggataa gggcagggtt cacccaccat
     1441 atcaagacgg taatcaggaa cgatattttt catgcgatct ccttagcagt ctgcggtgcc
     1501 gcacggcgga agaagcgttt ttcccagcca ataatcaaca ttagagcagc aaacaacagc
     1561 aaatatgtca ccagcaggcc gcccatcggg ccaaaggttt tcagcaggtt gattttgtcc
     1621 cagtcggtgg ccagcgccgg agcgaaatca tcccagtagt acgccagaat cgttgagccg
     1681 atcacgttgc ccagaccgac ccaccagtag tgcacctggc cttctaccgc gcggtacatc
     1741 cagccggttt cgcagccgcc tgccagcacg atgccaaaac caaacagtaa accaccaatt
     1801 accgcgtttg gtcccgccca catgattttg ggttcaacgc ctaactgtac gtaactgaag
     1861 atcccgatgg cacttaccgc cataccgata atgattgctt tcgccatatg ggtacgtccg
     1921 gtgatccaca tgtcgcggaa cgccgaagta aagcagattt gcgcacgttc aatcagtaaa
     1981 ccaaagccga cgccaaacag cattgccagc cccagtttgg gctggttcat cgccgtcagc
     2041 agcgcccagc ccagcaggcc gaaaaagacc agcatcccga gacgaaaacg acgccgcgcc
     2101 tgatccggtt tttgcgtcaa cggtgaggca gcagaaactt tctgcatttt cacgggaata
     2161 cggaagatgg gcagaagggt aaagcgcgcg ccaaaccatg aaccaatggc agtggcgatg
     2221 gcaaagaacc aggcgtgcag cgagaactgt ggaattccgg taaagaacgc cgccaggtta
     2281 cagcccattg ccagacgtgc gccaaaaccg gcgataatac cgccaatgat ggcctgcata
     2341 atgcggatac ggctgcgcgg catgcgcagt ttgacattgt tggcccacag cgctgcggca
     2401 aaacagccgc caaacatacc gaggatcatc attccgtcga tgcgggttaa tggcgatcct
     2461 tccagatgga taattttaaa ataaccccac tcttcagcat ggacgccgaa caactgcagg
     2521 agctgaccgc cccaacgggt aaattcacct gtgacagccc aaaaggtgcc agtgatgcca
     2581 aaatagtaag tggagagaat acccgccgcg atgaccgcgg ggatgggcgc ccagaattta
     2641 attaaccagg cgtgtttgaa ttgctgccat gacatgaatg tagcctctga actcagaagg
     2701 tttgaaacaa gagtcgcgaa tcatacacca tgcaaattta ttttcggggt aataattcac
     2761 aaaaataatg gttagatcaa atttctctct gaacctggaa aggctggcga catcagggct
     2821 ttaatgccac aatcctcttt tcttctcatg caggacgaat gatgaaaaaa ctcgcaattg
     2881 caggtgcgct catgttgctg gcgggctgtg ccgaagtcga aaactataac aatgtcgtga
     2941 aaacccccgc gccggactgg ctggcgggct actggcagac caaagggccg caacgtgcgt
     3001 tggtcagtcc ggaagcgata ggcagcctca ttgtcactaa agagggcgat accttggatt
     3061 gccgtcagtg gcagcgggtg attgccgtgc cgggtaagtt gacattgatg tctgatgatc
     3121 tcactaacgt taccgtaaaa cgtgagctgt acgaggttga gcgtgacggt aacaccattg
     3181 agtacgatgg tatgacgatg gagcgtgtgg atcgcccgac ggcagagtgt gccgccgcgc
     3241 tggataaagc gccgttaccg acgccactgc cgtaatgaaa tctccccggc ttgccgccgg
     3301 ggatggattt aaatcacctc ttcgataacc cacacgctga cgctgccgcc gttgcaaaag
     3361 aaggtcgctt cgccgttttc gtctgtcact acgctctctt gccggttccc cagaaaatca
     3421 cgccaggttt tattgccgta attctctccc agatgaatgg ttttttcgcc atcatctccg
     3481 ttcgacatga ccaccacgca gccgggatat tcgtcggtgc cactgcggct aaaggcaatg
     3541 cagttcggat ggtcgaaaaa taacgtctgt acaccgtggg cgaaacgctg acgggcgaga
     3601 attaactcat caagctgttc gattattggc atatctatcg gataggtttg cccgtcacca
     3661 ccgacatctt cgtaatgtgc accgtagagg tccggataga acaccgaagg aacgccattt
     3721 tcccgcaaca aaattaaggc atacgccagc ggtttaaacc acggttcgac gggggcttcg
     3781 agggcttgca acggttgggt gtcgtggttg gcaacgaggg ttacggcgtg aaaaggatcg
     3841 gcttccacca gcgtcccagt gaagatctgc gtcatgtcgt agtcgcgacc catgcgcgat
     3901 gcttcatgga atttcatctg cagcggcgca tcaaacagca tggttttgcc ttccacctga
     3961 tcaatatacg tttgcagttt atcgacttca tgcgaccagt attcagccac aataaacaac
     4021 ggctttggcg caacttcctg tacgtgttcg atccactctt tataaaacca tgccggaata
     4081 tgtttgaccg catcaagacg aaagccgtcg cattgcgttt gttccatcac ccagcgcgcc
     4141 cagtatttaa tctcttccgt cacggcatga ttgcgaaaat cgatattctc ccccatcaga
     4201 taatcgaaat taccgagttc atcatcaacc tgatcgttcc agccttctcc ggtatagtcg
     4261 ttaacaattt taaaaatgcc atcttcatca gggttttcga tatggtcgat accgctaaaa
     4321 catttgaaat cccagataaa ctgcgagtat tgcccggcac gagcggggaa ggtgtaacgc
     4381 gtccagcctt cacactcaat gatttcttcg tcaatttgcg tacggtcatc agcatttaca
     4441 cgctgcacgc gaatagcttc tttttcatcc gcgcccattt tgtggttgac taccacgtcc
     4501 agcagcaccg caatgtcatt acgtttcagg gcgtcaatgg cggccagcag ttgtgcttta
     4561 tcaccatatt tagtagggat gctgcctttc tgatcaaact cacctagatc aaataaatca
     4621 taggagtcgt agccgaccga atagccgccc gatgcgcctt tataggcggg cggcaaccag
     4681 accatattga taccaatatc attaaaaccg tctgcgcgct cggccagttc aggccagagc
     4741 ttaccgcctt ccgggtaata ccagtgaaaa cattgtaaca gcgtgggatt acgcattctt
     4801 cgactccatt caaggggaat attagaagcg tagccgtaat cggattattc gcgagccatc
     4861 ggctcattaa gattcaaaag aggttatcct gcggagccag cacaaagccg ccctgatcgc
     4921 cataggcact taacaccgat ttttgcaccg atgactgacc gaccagtttc gccagttcat
     4981 ccatccgaat ctgtaataac tgttttacct tgctttcgtt gtcgagaatc aggcgcagca
     5041 tcgggcggag ctgctcctgc atcgtagtgg acggggcaac ctcttcagtc aggtgtgcga
     5101 tctcctgcac cgcattcaca tacgccattt cgctggcgat gagttcgtcc cattgttctt
     5161 ccgttgccag gcgtaacatg agctggcttt tttcgacgag ttgttgccag gcgaaataca
     5221 aatgcggtgc attgttcatc agactgggtc ctgaatcaaa gaaggggaga gtaaagactc
     5281 tttccaggca tcggcaatat tgcgcattaa tgcttccact tcttcgactg cggagacatc
     5341 gttacgtaaa ttggcttgca gcaagcgcct gaccatatag ctataaagag caatcaagtt
     5401 ttgggttaat tcgtctttgc tctcttcatc aagactcacc cgcagtccgt tctcaatgat
     5461 gttgatcgct tttgataaag agacgccttt gccttgctga ttgttgtctt gcataaacag
     5521 gcgcgctcta accagtgcgc tcagcactcc atcaaatagc atggtgacca gctgctgttg
     5581 gctggcgctc attacggcgc tttcgacgcc aatttgtgca taggcctggg tgccttttgc
     5641 cgcgtacata gtctctcctg aagattattt cgagttgcta tttgaggtgt cgaactgctg
     5701 tgtcagatag ctactagtgg agttcagcga gttcattaac acatctaatt gggtgaactg
     5761 ggctttatag cgcgtcatta aggtatcgat acgttcactg gctgcgttgt actggtcggt
     5821 caaattattc agcgttttgc tgacgccatc ttttgctgcc tggattatcc cggtggaaga
     5881 gagccaactg gtcaggttgt tactaatgcc ggtggttacc ccagtacttt tgccgtcacc
     5941 tataaacatt tcaccgatac cagcggcatc attttttagc gccgtttgca gtttgtcggt
     6001 cgcgatttcc agcttgccgg tactggcatc gctggtaatg ccaatctgtg ccagcgtttt
     6061 atagtttgaa ctgctgtgag tattggcgag caaggtttta agctgagtct ggatggtacg
     6121 cagtgtggag tcaccgagta atgcgccatt actggagtcc tgactttcag ctccggcatc
     6181 gacagcggtg tatttggtta agctgctgaa tgtatcctgc aatgtgttat aggcatccac
     6241 ccacgcttta accgcatttt cagctttgga tgtgtcttta ctgatggtca gtgtctgatt
     6301 accggtggtg acgtcattca ggttgagggt gatatcttcc agtgagtcgc tgatagtgtt
     6361 actgctgttt tcaatctcaa cgttattgac tgtcagtttg gcgttttgcg cggtgacgct
     6421 ttcaatcatg ccattgctgc tatcacccgg cgttccgttg taacccataa aactttccag
     6481 ggcgctgtcg ccgctgacgc taagtttcat agcgttattg ctgcccgtat cgttagcggt
     6541 gatggacaga cgatattcgc cgtttcccac attgatgata ctggcgctga caccagcttt
     6601 ggcgttgtta atggcatcgc gaatgccgga aagtgacgag ttacccgcgc tgatatcaat
     6661 cgtgaccgga tctttaccgc cgccttgttg gatggtcagt acgctatcgc tggtggcgat
     6721 ggcggcttta ctgtcttttt gactattttt tgttgtcagc gtctgtgcct gcgccagttg
     6781 gctaacgcta atggtgtatt tcccagcaat cgcgctgccc gtggtggtgg cgctgaaagc
     6841 cgatgaactg ctggtggttg aggtggcggt aaataaatcg gctttattca gtgctgtgtt
     6901 ggctgtctgg aaactctcta gtgcactttt cagcgtcccg taggcgctca gtttcgcggt
     6961 gtaagagctt tgctgttttg atatcggcgt cagggtagat ttttctgccg cctccagact
     7021 gtcaaggatg ctgcttaagt ccagccccga cccaacccca agcgttgaaa tactagccat
     7081 atagtttcct taatcatgcg acgtgtatag aacgaatacc ggggttatcg gcgtaagcgg
     7141 ggtaaagttt acgatttatt ttttgcctta atggcacgaa cagcaacgag gaaggggagt
     7201 atttcgaccg ctagaaaaaa attctaaagg ttgtgagtga ccagacgata acagggttga
     7261 cggcgacgaa gccgaagggt ggaagcccaa tacttaaacc gtagacttga aaacaggaaa
     7321 atgaattatg gcacaagtca ttaataccaa cagcctctcg ctgatcactc agaacaacat
     7381 caacaaaaac cagtctgcgc tgtcgacttc tatcgagcgc ctctcttctg gtctgcgtat
     7441 taacagcgct aaagatgacg ccgcgggcca ggcgattgct aaccgcttta cttctaacat
     7501 caaaggtctg actcaggccg cacgtaacgc caacgacggt atttctctgg cgcagacggc
     7561 tgaaggcgcg ctgtcagaga ttaacaacaa cttgcagcgt attcgtgaac tgaccgttca
     7621 ggcctctacc ggcacgaact ctgattccga cctgtcttct attcaggacg aaatcaaatc
     7681 ccgtcttgat gaaattgacc gtgtatctgg tcagacccag ttcaacggtg tgaacgtgct
     7741 gtcgaaaaac gattcgatga agattcagat tggtgccaat gataaccaga cgatcagcat
     7801 tggcttgcaa caaatcgaca gtaccacttt gaatctgaaa ggatttaccg tgtccggcat
     7861 ggcggatttc agcgcggcga aactgacggc tgctgatggt acagcaattg ctgctgcgga
     7921 tgtcaaggat gctgggggta aacaagtcaa tttactgtct tacactgaca ccgcgtctaa
     7981 cagtactaaa tatgcggtcg ttgattctgc aaccggtaaa tacatggaag ccactgtagc
     8041 cattaccggt acggcggcgg taactgttgg tgcagcggaa gtggcgggag ccgctacagc
     8101 cgatccgtta aaagcactgg atgccgcaat cgctaaagtc gacaaattcc gctcctccct
     8161 cggtgccgtt caaaaccgtc tggattctgc ggtcaccaac ctgaacaaca ccaccaccaa
     8221 cctgtctgaa gcgcagtccc gtattcagga cgccgactat gcgaccgaag tgtccaacat
     8281 gtcgaaagcg cagattatcc agcaggcggg caactccgtg ctgtctaaag ccaaccaggt
     8341 accgcagcaa gttctgtctc tgttacaagg ctaatggcct taacctgcct gaccccgcta
     8401 ccggcggggt tttttctgcc cgcaatttac cggtaacccc caaataaccc ctcatttcac
     8461 ccactaatcg tccgattaaa aaccctgcag aaacggataa tcatgccgat aactcatata
     8521 acgcagggct gtttatcgtg aattcactct ataccgctga aggtgtaatg gataaacact
     8581 cgctgtggca gcgttatgtc ccgctggtgc gtcacgaagc attgcgcctg caggttcgac
     8641 tgcccgcgag cgtggaactt gacgatctgc tacaggcggg cggcattggg ttacttaatg
     8701 ccgtcgaacg ctatgacgcc ctacaaggaa cggcatttac aacttacgca gtgcagcgta
     8761 tccgtggcgc tatgctggat gaacttcgca gccgtgactg ggtgccgcgc agcgtgcgac
     8821 gcaacgcgcg tgaagtggca caggcaatag ggcaactgga gcaggaactt ggccgcaacg
     8881 ccacggaaac tgaggttgcg gaacgtttag ggatcgatat tgccgattat cgccaaatgt
     8941 tgctcgacac caataacagc cagctcttct cctacgatga gtggcgcgaa gagcacggcg
     9001 atagcatcga actggttact gatgatcatc agcgagaaaa cccgctacaa caactgctgg
     9061 acagtaatct gcgccagcgg gtgatggaag ctatcgaaac gttgccggag cgcgaaaaac
     9121 tggtattaac cctctattac caggaagagc tgaatctcaa agagattggc gcggtgctgg
     9181 aggtcgggga atcgcgggtc agtcagttac acagccaggc cattaaacgg ttacgcacta
     9241 aactgggtaa gttataacgt cagtaaatgc cgcactttaa ttttgactac caggagttct
     9301 taatgatggt gcagcacctg aaaagacggc cattaagccg ctatcttaaa gactttaaac
     9361 acagccagac ttattgcgcg cattgccgta aattactcga tcgcattacc ctcgttcgcg
     9421 acggcaaaat agtgaataaa atcgagattt ccctcctgga cgcgctgctt gatgaaaatg
     9481 gctggcaaac ggaacaaaaa tcatgggcgg cattgtgccg attttgcggt gatttacatt
     9541 gcaaaacgca gagtgatttt ttcgatatta tcggctttaa gcaatttctt tttgagcaaa
     9601 ctgaaatgag cccaggtacg gtgcgtgaat atgtcgttcg tttgcgccgt ttggggaatc
     9661 atctacacga gcaaaatatt tccctcgatc agctgcagga cggtttcctt gatgaaatcc
     9721 tcgccccgtg gctgcccacc accagcacca acaattaccg catcgcatta cggaagtatc
     9781 aacactatca gcgtcaaacg tgtaccggac ttgtgcagaa atcctccagc ctgcctgctt
     9841 ctgatatata ttaaataaga ataagatgta gcggagttgt ttttgtgttt acaaacaatg
     9901 gctctacact gcaaacagac ataacaacat tcggggtaaa tatgaaatta gcacatctgg
     9961 gacgtcaggc attgatgagt gtgatggccg tagcgctggt tgcgggcatg agcgttaaaa
    10021 gttttgcaga tgaaggtctg cttaataaag ttaaagagcg cggcacgctg ctggtagggc
    10081 tggaaggcac ttatccgccg ttcagttttc agggggatga cggcaaatta accggttttg
    10141 aagtggaatt tgcccaacag ctggcaaaac atcttggcgt tgaggcgtca ctaaaaccga
    10201 ccaaatggga cggtatgctg gcgtcgctgg actctaaacg cattgatgtg gtgattaatc
    10261 aggtcaccat ttctgacgag cgcaagaaaa aatacgattt ctctacccct tacaccattt
    10321 ccggtattca ggcgctggtg aaaaaaggta acgaaggcac ccttaaaacg gctgctgatc
    10381 tgaaaggcaa aaaagtgggt gtcggtctgg gcaccaacta tgaagagtgg ctgcggcaga
    10441 atgttcaggg cgtcgatgtg cgtacctatg atgatgaccc gaccaaatat caggatctgc
    10501 gcgtagggcg tatcgatgcg atcctcgttg atcgtctggc ggcgctggat ctggtgaaga
    10561 aaaccaacga tacgctggca gtaaccggtg aagcattctc ccgtcaggag tctggcgtgg
    10621 cgctgcgtaa aggaaatgag gacctgctga aagcggtgaa tgatgcaatt gcggaaatgc
    10681 aaaaagacgg cactctgcaa gctctttccg aaaaatggtt tggtgctgat gtgaccaaat
    10741 aatcagcata atgacaaaaa agggcgcttt cactagcgcc ttttttattt acgcgttttc
    10801 agcgtgcata ataagaaaat cacaacaaca cacatcggag gctgttatgc cactgcataa
    10861 tttaacccgt tttccacggt tggagtttat cggcgcgcca acgccgctcg aatatctgcc
    10921 gcgcttttct gattatcttg gacgggaaat tttcatcaaa cgggatgacg tcacccccat
    10981 ggcaatgggc ggcaataaat tacgtaagct ggaatttctc gcagcagatg ctctgcgcga
    11041 aggtgccgat acgctgatta ctgccggcgc gatccagtct aaccatgtgc gccagactgc
    11101 cgcagttgcg gcgaaactcg gtctgcactg cgtggcgctg ctggaaaatc ctattggcac
    11161 aaccgcagaa aactatttaa ccaacggcaa tcgcttgttg ctggatctgt tcaataccca
    11221 gattgaaatg tgcgacgcac tgaccgatcc caatgcccaa ctggaagagc tggcgacgcg
    11281 agtcgaagca caaggctttc gcccgtatgt cattccggtt ggcggttcta atgctttggg
    11341 cgcgctgggt tatgtggaga gtgcgctgga aatcgcgcaa cagtgtgaag gggcggttaa
    11401 tatttcgtcg gtggtagtcg catcgggcag tgccggaact cacgccggac tggctgttgg
    11461 gctggaacac ctgctgcctg aaagcgaact gattggcgtg accgtgtcgc gttccgttgc
    11521 cgatcaattg ccgaaagtgg ttaacctaca acaggcgatt gcgaaagaac tggagctgac
    11581 cgcatcagcg gaaattttac tctgggatga ctattttgca cctggctacg gcgtgccgaa
    11641 cgacgaaggc atggaagcag tgaaattgct ggcgcggttg gaaggcattc tgcttgatcc
    11701 tgtgtatacc ggaaaagcga tggcgggtct gattgacggt atcagtcaga aacgcttcaa
    11761 agatgaaggg ccgattctgt ttattcatac cggcggcgcg cctgcgctgt tcgcctatca
    11821 tccccacgtt tagctccggg aacgctcatg caagaaagta tacaactggt tattgattcc
    11881 ttgccgttcc tgctgaaagg ggctgggtat acgctgcaac tcagtatcgg cggcatgttt
    11941 tttggcttac tgctcgggtt tattctcgcg ctgatgcgcc tgtcgccaat ctggcccgtg
    12001 cgctggctgg cgcgttttta tatctctatt tttcgtggta cgccgctcat cgcacaactg
    12061 tttatgatct attacggcct gccgcagttt ggtatcgaat tagatcccat tccgtcagca
    12121 atgattggtc tgtcgctgaa cactgccgcc tatgctgccg aaacgctgcg cgccgccatt
    12181 tcttctattg ataaaggtca gtgggaagca gctgccagta ttggtatgac gccatggcag
    12241 actatgcgtc gcgcgatttt gccacaggcg gcgcgggtgg cgttgccgcc gctgtcgaac
    12301 agctttatca gtctggtaaa agatacgtcg ctggccgcga caatccaggt gccggagctg
    12361 ttccgtcagg cgcagttgat tacctcgcgt acgctggagg tattcaccat gtatctggcg
    12421 gcttcgctca tctactggat catggcgact gtgttatcga cgttgcagaa ccattttgag
    12481 aatcaactta atcgccagga gagagaacca aaatgagtgc cattgaagtt aagaacctgg
    12541 tgaaaaaatt tcacggtcag acggtgctgc acggtatcga ccttgaggta aagcctggcg
    12601 aagtggtggc aattatcggt ccgagtggtt ccggcaaaac cacgttgcta cgcagcgtaa
    12661 atctgctgga acaacccgaa gcgggaacga tcaccgttgg cgatatcact attgatactg
    12721 cacgttcatt aagtcagcaa aaatcgctga ttcgccagtt gcgtcagcac gtcgggtttg
    12781 tcttccagaa ctttaatttg tttccgcatc gtacggtgct ggaaaacatt attgaagggc
    12841 cggtgatcgt caaaggcgaa ccgaaagaag aggccacggc gcgcgctcgc gagctgttgg
    12901 cgaaagttgg gctggccggt aaagaaacca gctatccacg tcgtttgtct ggcggtcaac
    12961 agcaacgtgt tgcgattgca cgtgcgctgg caatgcgtcc tgaggtgatt ttgtttgacg
    13021 agccaacgtc ggcgctggat ccagagctgg tgggcgaagt cctgaacacc atccgtcagc
    13081 tggcgcagga aaagcgcacg atggtgattg tgacgcacga aatgagcttt gcccgggatg
    13141 ttgcggaccg ggcgattttt atggaccagg ggcggatagt cgagcagggg gcagcaaaag
    13201 cgttatttgc cgatccccag cagcctcgca cccgccagtt cctcgagaag tttctgctgc
    13261 aataataaga aaaaatcagc cccgacgatt cacctgtcgg ggcgggacgc catttcaagc
    13321 gtgataaaac agcttaacaa atcagcataa ctcattaata acataagaga atgcgatggc
    13381 ttgcaaaagt aattcattgc ctgaataata taaattatat ataaatctta tttatgtgat
    13441 agtttgaatt atcattataa atgatactca ctctcagggg cgttgcggtt tactatgcag
    13501 gatacggatt ttttcagctg gcgtcgcacg atgctgttgc gttttcagag gatggaggcc
    13561 gcagaagagg tctaccatga aatagagctt caggctcagc agctagagta cgattactat
    13621 tcgttatgtg ttcgccaccc ggtaccattc acgcgaccta aagtggcttt ctacaccaat
    13681 taccctgagg cgtgggttag ttattatcag gcaaaaaact ttctcgcaat tgatccggtg
    13741 ctgaaccctg aaaactttgt cagggccatt taatgtggaa tgatgactta ttcagcgaag
    13801 cacagccgtt atgggaagcc gcgcgcgcac atggtttacg ccgcggtgtc actcagtatt
    13861 taatgctgcc aaaccgggcg ctgggctttt tgtccttttc ccgtagcagc gcgcgcgaaa
    13921 tacccattct tagtgatgaa ctgcaattaa aaatgcagtt actggtgcgc gaaagtctga
    13981 tggctctgat gcgtttaaat gatgaaatag tgatgacgcc agagatgaat ttcagcaagc
    14041 gcgaaaaaga aattttgaaa tggacggcgg aagggaagac atcagcagag atagcgatga
    14101 ttttgtcaat ctctgagaat acggtcaatt tccatcagaa aa
//
LOCUS       DADXDL010000111        13870 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.111, whole genome shotgun sequence.
ACCESSION   DADXDL010000111 DADXDL010000000
VERSION     DADXDL010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13870
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.111"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            22..690
                     /locus_tag="IRB70_004126"
     CDS             22..690
                     /locus_tag="IRB70_004126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001491073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine Rich Repeat family protein"
                     /protein_id="HBC0633971.1"
                     /translation="MINDLILHNHPIVEKITLNDNHIAHLNAKTTTKLEYLNLSNNNL
                     LPTDDIDQLISSKHLWHVLVNGINNDPLAQMQYWTAVRNIIDDTNEVTIDLSYNLAIT
                     NIDTSDEHLVEVSENSEGNHIKDNDSMSIRYRSKYYSREYALIEEETIFSDAELKAIL
                     PMHRMYGVGDYKSNSSSLPSHSGLKDPTGTPVCYYIHNEDKPSLGFGPTSNNWLSQSF
                     TTEL"
     gene            753..2009
                     /locus_tag="IRB70_004127"
     CDS             753..2009
                     /locus_tag="IRB70_004127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000671707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HBC0633972.1"
                     /translation="MKFPSIFNKINPQSIQQHPEKNELNWMLELNQWKAERILTGEIH
                     RPECRNEAAKRINCAFLSKQNDIDLSGLNLTTQPPGLQNFTSINLDNNQLTHFDTTTY
                     DRLVKLSLNSNALESINFPQGRNVSITHISMNNNSLRNIDIDRLSSITYFSAAHNQLE
                     FVQLECCERLQYLNLSHNQLTDIVAGNKDELLLLDLSNNKLTSLHNALFPNLNTLLIN
                     NNLLSGIKIFFSNFCNVQTLNAANNQLEKINLHFLTYLSSIKSLRLDNNKITRIDTKN
                     TSDIGTLFPIIKQSKNLNFLNVSGKNNCPTMQLMLFNLFSPALKLNTGLAILSPGAFE
                     VHSDGVDVDNELFHYTIKEAYTPYNIHTYKTEEVVNQMNIKTKNMTLDEINNTYCNND
                     YYNEAIREEPIDFLGRSFSSSSWPFQ"
     gene            2319..3707
                     /gene="narU"
                     /locus_tag="IRB70_004128"
     CDS             2319..3707
                     /gene="narU"
                     /locus_tag="IRB70_004128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate/nitrite transporter NarU"
                     /protein_id="HBC0633973.1"
                     /translation="MALQNEKNSRYLLRDWKPENPAFWENKGKHIARRNLWISVSCLL
                     LAFCVWMLFSAVTVNLNKIGFNFTTDQLFLLTALPSVSGALLRVPYSFMVPIFGGRRW
                     TVFSTAILIIPCVWLGIAVQNPNTPFGIFIVIALLCGFAGANFASSMGNISFFFPKAK
                     QGSALGINGGLGNLGVSVMQLVAPLVIFVPVFAFLGVNGVPQADGSVMSLANAAWIWV
                     PLLAIATIAAWSGMNDIASSRASIADQLPVLQRLHLWLLSLLYLATFGSFIGFSAGFA
                     MLAKTQFPDVNILRLAFFGPFIGAIARSVGGAISDKFGGVRVTLINFIFMAIFSALLF
                     LTLPGTGSGNFIAFYAVFMGLFLTAGLGSGSTFQMIAVIFRQITIYRVKMKGGSDEQA
                     QREAVTETAAALGFISAIGAVGGFFIPQAFGMSLNMTGSPVGAMKVFLIFYIVCVLLT
                     WLVYGRRKFSQK"
     gene            3802..7542
                     /gene="narZ"
                     /locus_tag="IRB70_004129"
     CDS             3802..7542
                     /gene="narZ"
                     /locus_tag="IRB70_004129"
                     /EC_number="1.7.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase Z subunit alpha"
                     /protein_id="HBC0633974.1"
                     /translation="MSKLLDRFRYFKQKGETFADGHGQVMHSNRDWEDSYRQRWQFDK
                     IVRSTHGVNCTGSCSWKIYVKNGLVTWEIQQTDYPRTRPDLPNHEPRGCPRGASYSWY
                     LYSANRLKYPLIRKRLIELWREALKQHSDPVLAWASIMNDPQKCLSYKQVRGRGGFIR
                     SNWQELNQLIAAANVWTIKTYGPDRVAGFSPIPAMSMVSYAAGTRYLSLLGGTCLSFY
                     DWYCDLPPASPMTWGEQTDVPESADWYNSSYIIAWGSNVPQTRTPDAHFFTEVRYKGT
                     KTIAITPDYSEVAKLCDQWLAPKQGTDSALAMAMGHVILKEFHLDNPSDYFINYCRRY
                     SDMPMLVMLEPRDDGSYVPGRMVRASDLVDGLGESNNPQWKTVAVNTAGELVVPNGSI
                     GFRWGEKGKWNLESIAAGTETELSLTLLGQHDAVAGVAFPYFGGIENPHFRSVKHNPV
                     LVRQLPVKNLTLADGNTCPVVSVYDLVLANYGLDRGLEDENSAKDYAEIKPYTPAWGE
                     QITGVPRQYIETIAREFADTAHKTHGRSMIILGAGVNHWYHMDMNYRGMINMLIFCGC
                     VGQSGGGWAHYVGQEKLRPQTGWLPLAFALDWNRPPRQMNSTSFFYNHSSQWRYEKVS
                     AQELLSPLADASKYSGHLIDFNVRAERMGWLPSAPQLGRNPLGIKAEADKAGLSPTEF
                     TAQALKSGDLRMACEQPDSGSNHPRNLFVWRSNLLGSSGKGHEYMQKYLLGTESGIQG
                     EELGASDGIKPEEVEWQTAAIEGKLDLLVTLDFRMSSTCLFSDIVLPTATWYEKDDMN
                     TSDMHPFIHPLSAAVDPAWESRSDWEIYKGIAKAFSQLCVGHLGKETDVVLQPLLHDS
                     PAELSQPCEVLDWRKGECDLIPGKTAPNIVAVERDYPATYERFTSLGPLMDKLGNGGK
                     GISWNTQDEIDFLGKLNYTKREGPAQGRPLIDTAIDASEVILALAPETNGHVAVKAWQ
                     ALGEITGREHTHLALHKEDEKIRFRDIQAQPRKIISSPTWSGLESDHVSYNAGYTNVH
                     ELIPWRTLSGRQQLYQDHPWMRAFGESLVAYRPPIDTRSVSEMRQIPPNGFPEKALNF
                     LTPHQKWGIHSTYSENLLMLTLSRGGPIVWISETDARELTIVDNDWVEVFNANGALTA
                     RAVVSQRVPPGMTMMYHAQERIMNIPGSEVTGMRGGIHNSVTRVCPKPTHMIGGYAQL
                     AWGFNYYGTVGSNRDEFIMIRKMKNVNWLDDEGRDQVQEAKK"
     gene            7539..9083
                     /gene="narH"
                     /locus_tag="IRB70_004130"
     CDS             7539..9083
                     /gene="narH"
                     /locus_tag="IRB70_004130"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase subunit beta"
                     /protein_id="HBC0633975.1"
                     /translation="MKIRSQVGMVLNLDKCIGCHTCSVTCKNVWTRREGMEYAWFNNV
                     ETKPGIGYPKNWEDQEEWQGGWVRDVNGKIRPRLGSKMGVITKIFANPVVPQIDDYYE
                     PFTFDYEHLHSAPEGKHIPTARPRSLIDGKRMDKVIWGPNWEELLGGEFEKRARDRNF
                     EAMQKEMYGQFENTFMMYLPRLCEHCLNPSCVATCPSGAIYKREEDGIVLIDQDKCRG
                     WRLCISGCPYKKIYFNWKSGKSEKCIFCYPRIESGQPTVCSETCVGRIRYLGVLLYDA
                     DRIEEAASTEREVDLYERQCEVFLDPHDPSVIEEALKQGIPQNVIDAAQRSPVYKMAM
                     DWKLALPLHPEYRTLPMVWYVPPLSPIQSYADAGGLPKSEGVLPAIESLRIPVQYLAN
                     MLSAGDTGPVLRALKRMMAMRHYMRSQTVEGVTDTRAIDEVGLSVAQVEEMYRYLAIA
                     NYEDRFVIPTSHREMAGDAFAERNGCGFTFGDGCHGSDSKFNLFNSSRIDAINITEVR
                     DKAEGE"
     gene            9083..9778
                     /gene="narW"
                     /locus_tag="IRB70_004131"
     CDS             9083..9778
                     /gene="narW"
                     /locus_tag="IRB70_004131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase molybdenum cofactor assembly
                     chaperone"
                     /protein_id="HBC0633976.1"
                     /translation="MQILKVIGLLMEYPDELLWECKEDALALIRRDAPMLTDFTRNLL
                     NAPLLDKQAEWCEVFDRGRTTSLLLFEHVHAESRDRGQAMVDLLAEYEKVGLQLDCRE
                     LPDYLPLYLEYLSVLPDDQAKEGLLNVAPILALLGGRLKQREAPWYALFDTLLQLAGS
                     PLSSDSVTKQIRSEERDDTRQALDAVWEEEQVKFIEDNATACDSSPLNQYQRRFSQDV
                     APQYVDISAGGGK"
     gene            9775..10455
                     /gene="narI"
                     /locus_tag="IRB70_004132"
     CDS             9775..10455
                     /gene="narI"
                     /locus_tag="IRB70_004132"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="respiratory nitrate reductase subunit gamma"
                     /protein_id="HBC0633977.1"
                     /translation="MIQYLNVFFYDIYPYLCGTVFILGSWLRYDYGQYTWRAASSQML
                     DKRGMVLWSNLFHIGILGIFFGHLFGMLTPHWMYAWFLPVAAKQLMAMILGGICGVLT
                     LIGGAGLLVRRLTNPRIRATSSGADILILAILLIQCILGLTTIPFSAQHPDGSEMMKL
                     VGWAQSIVTFQGGASTHLDGVAFIFRVHLVLGMTIFLLFPFTRLVHVWSAPFEYFTRR
                     YQIVRSRR"
     gene            10535..11428
                     /locus_tag="IRB70_004133"
     CDS             10535..11428
                     /locus_tag="IRB70_004133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family isomerase"
                     /protein_id="HBC0633978.1"
                     /translation="MKPQVYHVDAFTSQPFRGNSAGVVFPADNLSEAQMQLIARELGH
                     SETAFLLHSDDSDVRIRYFTPTVEVPICGHATVAAHYVRAKVLGLGNCTVWQTSLAGK
                     HRVTIEKQNDDYRISLEQGTPGFEPPLKGETRAAIINALHLTEDDILQGLPIQVATTG
                     HSKVMIPLKPEVDIDALSPDLAALTTISKQIGCNGFFPFQIRPGKNETDGRMFSPAIG
                     IVEDPVTGNANGPMGAWLVHHNVLPHDGNVLRVKGHQGRALGREGVIEVTVTIRDNQP
                     EKVTISGTAVILFHAEWAIEL"
     gene            complement(11524..12369)
                     /gene="nhoA"
                     /locus_tag="IRB70_004134"
     CDS             complement(11524..12369)
                     /gene="nhoA"
                     /locus_tag="IRB70_004134"
                     /EC_number="2.3.1.118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-hydroxyarylamine O-acetyltransferase"
                     /protein_id="HBC0633979.1"
                     /translation="MTPILNHYFARINWLGAAAANIDTLRALHLKHNCTIPFENLDVL
                     LPREIQLDDQSLEEKLVIARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPAL
                     PPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLMPDIMQTTPHGEYRLLQEGDDWVL
                     QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLT
                     NFHFTHYENGHAVKQRNLPDVASLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTH
                     PEAGK"
     gene            12544..13113
                     /locus_tag="IRB70_004135"
     CDS             12544..13113
                     /locus_tag="IRB70_004135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415979.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBC0633980.1"
                     /translation="MSQFIPVELHHASRLLNHGPTVMITSFDEQSQRRNIMAAAWSMP
                     VEFEPPRVAIVVDKSTWTRELIERNGKFGIVIPGVAATNWTWAVGSVSGRDEDKFNCY
                     GIPVVKGPVLGLPLVEEKCLAWMECRLLPATSAQEKYDTLFGEVVSAAADARVFVEGR
                     WQFDDDKLNTLHHLGAGTFVTSGKRVTAG"
     gene            complement(13117..13344)
                     /gene="pptA"
                     /locus_tag="IRB70_004136"
     CDS             complement(13117..13344)
                     /gene="pptA"
                     /locus_tag="IRB70_004136"
                     /EC_number="5.3.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tautomerase PptA"
                     /protein_id="HBC0633981.1"
                     /translation="MPHIDIKCFPRELDEQQKAALAADITDVIIRHLNSKDSSISIAL
                     QQIQPESWQAIWDAEIAPQMETLIKKPGYSM"
     gene            complement(13728..>13870)
                     /locus_tag="IRB70_004137"
     CDS             complement(13728..>13870)
                     /locus_tag="IRB70_004137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0633982.1"
                     /translation="FSGIRHIAIDILTNDKVFKAGLRRKMRKAVMDRNYLASVLAGSG
                     LS"
BASE COUNT         3548 a         3463 c         3367 g         3492 t
ORIGIN      
        1 gagttaagtg cccatcacaa catgatcaat gaccttatat tacacaatca ccccatagtg
       61 gagaaaatca ctttaaacga caaccatatt gcacatttaa acgcgaaaac cactacaaaa
      121 ctggaatatt taaacttaag caataacaat ttattgccaa cagatgacat tgatcaatta
      181 atatcatcaa aacatctttg gcatgtatta gttaacggca tcaacaatga tccacttgcc
      241 caaatgcagt actggactgc agtaagaaat ataattgatg acactaatga agtgaccatt
      301 gatttatctt ataacctggc aattacaaat atcgatacca gcgatgaaca tcttgtagaa
      361 gtaagcgaga attccgaagg aaatcatata aaagacaatg actcaatgtc tattcgttat
      421 agatcaaaat attattccag agagtacgct ttaatagaag aagaaacaat attttctgac
      481 gcagaactaa aagccattct gcctatgcat cgcatgtacg gggttggtga ctataagtca
      541 aattcctctt ctctaccctc acactcgggg ctaaaggacc caacgggcac acccgtctgt
      601 tattatattc ataatgagga taaaccttcc ttaggttttg gtccaacatc caataattgg
      661 ttaagccaat cctttacaac agagttataa aacacatcct gatttatcaa gggtaataaa
      721 tcattaaaat aaagcattac tacggagcag ttatgaaatt cccttcaata tttaataaaa
      781 taaatccaca atccatacag caacatccag aaaaaaatga acttaactgg atgctcgaat
      841 taaatcaatg gaaagcagaa cgcatactta caggtgaaat ccatcgtccg gaatgccgaa
      901 acgaagccgc taaaaggata aattgtgctt ttttgtcgaa acagaatgat attgatttat
      961 caggacttaa tttaactacc caaccaccag ggctgcaaaa cttcacctct atcaatcttg
     1021 ataataacca actcacacat tttgatacaa ccacctacga tagactcgta aagcttagtc
     1081 tgaatagtaa tgctcttgag tcaataaatt ttcctcaagg cagaaatgta agcattacac
     1141 atatatctat gaataataat tctctcagaa atattgatat agataggctt tcatcaatta
     1201 cttattttag tgcggcacat aatcaactag agtttgtgca attagaatgt tgcgaaaggc
     1261 tgcagtacct gaatctcagc cacaatcaat taactgatat tgttgcagga aataaagatg
     1321 aactcttact tctggattta tccaataata aactaacaag tttacataat gccttatttc
     1381 ccaacttgaa tacgttactt atcaacaaca acttgctttc tggaattaaa atattcttta
     1441 gcaacttctg caatgttcag acattaaacg ctgcgaacaa tcagttggaa aaaataaacc
     1501 ttcatttcct gacttatctt tcatctatca aaagtttaag gctggacaat aataaaataa
     1561 cccgcattga cactaagaat acctccgata ttggaacttt attccccata ataaaacaga
     1621 gcaaaaactt aaatttttta aatgtttctg ggaagaacaa ttgccctact atgcagctca
     1681 tgttatttaa tttattttcc ccagcactta agcttaatac tggcctggca attctttcgc
     1741 ctggtgcatt tgaagttcac tctgacggag tagatgtgga taacgaattg tttcactata
     1801 ctattaaaga agcatatacc ccatataata tacacactta taaaacagaa gaagttgtaa
     1861 atcagatgaa tataaaaact aaaaatatga cattagatga aataaacaat acttactgta
     1921 ataacgatta ttacaatgag gcgataagag aggaaccgat agactttctg ggcagatcgt
     1981 tttcctccag ctcatggcct tttcagtgaa taaatcatca ctaattctat aattgtctgg
     2041 tcttgttgag aatatagtta atatgcaacc ctttagattc acgatctgaa gggttgaaac
     2101 atgacatacg ttcaaagatt aacccccgtt tgatggttac atttagtaac acatatctgt
     2161 ctgtttaatc cacattctgc ctccgcagtt acgctttctt atctattctt ctaatcagca
     2221 cttcacctga ttcatcctta attctaataa ctggctattg cgccttacct cctgttttgt
     2281 ctttttttca ttaccaatgt gtgcatgtga ggaacaatat ggcactgcaa aatgagaaaa
     2341 atagtcgtta tcttttacgc gactggaaac cagaaaatcc ggccttctgg gaaaataaag
     2401 gaaagcatat tgcacgaaga aacctctgga tatcagtcag ttgtctactt cttgccttct
     2461 gtgtctggat gctatttagc gcagttactg ttaatctcaa taaaatcggt tttaatttca
     2521 ctaccgatca actcttttta ttaaccgcat taccctccgt ttctggcgca ttattgcgtg
     2581 tcccctactc ctttatggtg cctatattcg gtggacgccg atggacggtt tttagtactg
     2641 caatcctgat tattccttgc gtctggctcg gaattgccgt gcagaatccg aatactcctt
     2701 ttgggatatt tatcgttatc gctttgctat gcggttttgc aggtgcgaac tttgcttcga
     2761 gcatgggcaa tatcagtttc ttcttcccaa aagccaaaca agggagcgca cttgggatta
     2821 atggcggatt aggaaactta ggtgtaagtg tgatgcagct ggttgcaccg ctggtcattt
     2881 ttgtacccgt atttgccttt ctcggcgtca atggcgtacc gcaggccgac ggttcggtga
     2941 tgtcgctggc gaatgccgca tggatttggg tgccattact ggcgattgcc acgatcgccg
     3001 cctggtcagg gatgaatgat atcgccagtt cacgcgcctc aattgccgac cagctccctg
     3061 tcttacaacg cctgcatctc tggctactga gcctgcttta tcttgccacc ttcggttcgt
     3121 ttatcggttt ttctgcgggt tttgccatgc tggcaaaaac ccagttcccg gatgtgaata
     3181 ttctgcgcct ggcgttcttt ggcccattta tcggtgccat cgcgcgatcg gttggtggtg
     3241 ctatttccga taaattcggc ggcgtgcggg tgacgttgat caacttcatt tttatggcga
     3301 ttttcagcgc cctgctgttc cttaccttac cgggcacagg ctccggtaat ttcatcgcat
     3361 tttacgccgt atttatgggg ctgtttctga ccgcgggtct gggaagtggt tctactttcc
     3421 agatgatcgc cgtcatcttt cgccagataa ccatttatcg ggtgaagatg aaaggcggta
     3481 gtgatgagca agctcaaaga gaagccgtca ccgaaacggc agccgctctg ggctttatct
     3541 cagccattgg cgcagtgggc ggctttttta ttccgcaggc gtttggcatg tcgctcaata
     3601 tgaccggctc tccggtgggc gcgatgaaag tgtttttaat cttctacatc gtttgcgtgc
     3661 tactgacctg gctggtttat ggtcggcgga agttcagcca aaaataagag atcgatgcct
     3721 gacacgtctt atcaggctac aaccgtgtcg cgtccgacaa ggcatcagat cccaattcat
     3781 tcctggagca ggagttatgt catgagtaaa cttttggatc gctttcgcta cttcaaacaa
     3841 aagggcgaaa cctttgccga tggtcacgga caggtgatgc atagcaaccg cgactgggag
     3901 gacagctatc gccagcgttg gcagttcgac aaaatcgtgc gttccaccca cggtgttaac
     3961 tgtacaggct cctgtagctg gaaaatctac gttaaaaatg gtctggtgac ctgggaaatc
     4021 caacagaccg actacccgcg cactcgccct gacctgccca atcatgaacc tcgcggctgc
     4081 ccgcgtggcg caagttactc ctggtatctc tacagcgcta accgtctgaa atacccgctc
     4141 attcgtaaac gactgattga actgtggcgc gaagccctca agcaacacag cgatccggta
     4201 ctggcgtggg catcgattat gaacgatccg caaaagtgcc tgagctacaa acaagtacgt
     4261 ggacgcggcg gctttatccg ctccaactgg caggagctaa accagctgat tgccgctgct
     4321 aacgtctgga ccatcaaaac ttacggcccg gatcgcgttg ccggtttctc gccgatcccg
     4381 gcgatgtcga tggtttctta cgccgccgga acacgttatc tgtcgctgtt aggtggcacc
     4441 tgtttaagct tctacgactg gtattgcgac ctgccgcccg cctcgccgat gacctggggc
     4501 gaacaaaccg acgtgccgga atctgccgac tggtataact ccagttacat catcgcctgg
     4561 gggtctaacg taccgcagac acgtacgccg gacgcccatt tctttaccga agtacgctac
     4621 aaaggcacta aaaccatcgc cattacccct gactactctg aagtggccaa attgtgcgac
     4681 cagtggctgg caccaaaaca aggcactgat agtgccctgg caatggcaat gggccatgtc
     4741 attttaaaag agtttcatct cgataatccc agcgattatt ttatcaacta ctgccgccgc
     4801 tacagcgaca tgccgatgct ggtaatgctg gaacctcgcg acgacggcag ctacgttccc
     4861 gggcgcatgg tccgcgcatc tgacctggtg gatggactgg gcgaaagcaa taatccgcag
     4921 tggaaaaccg tggcggttaa taccgcaggt gaactggtgg tgccgaacgg ttcgattggt
     4981 tttcgctggg gagaaaaagg caaatggaat ctggaatcca ttgccgccgg tacggaaacc
     5041 gaattgtcgt taactctgct cggtcaacat gatgccgttg caggcgtggc cttcccctac
     5101 tttggcggca ttgaaaatcc gcattttcgt agcgtaaaac acaatccggt cctggtgcgc
     5161 caattgcccg ttaaaaacct gacattagcc gatggcaaca cctgtccggt ggtcagcgtt
     5221 tatgatttgg tactggcgaa ttatggcctc gatcgcgggc tggaagatga aaacagcgcg
     5281 aaagattacg ctgaaatcaa accgtacacc ccagcctggg gtgagcaaat taccggtgtg
     5341 ccgcgccagt atattgaaac catcgctcgt gaatttgccg atactgccca taaaacgcat
     5401 gggcgctcga tgattatcct cggcgcaggt gttaaccact ggtaccacat ggacatgaat
     5461 taccgtggga tgatcaacat gctgatcttc tgcggttgtg tcgggcaaag cggtggcggc
     5521 tgggcacact atgtcggtca ggaaaaactg cgcccgcaaa ccggctggtt gccactggcc
     5581 tttgcgctcg actggaaccg accaccgcgc cagatgaaca gcacctcgtt tttctacaat
     5641 cattccagcc aatggcgcta tgaaaaagtc tctgctcagg agttactttc accgctggcc
     5701 gatgccagta agtacagcgg tcatctgatt gatttcaacg ttcgcgccga acgtatgggc
     5761 tggctacctt ctgcgccgca gttggggcgt aatccgctcg ggattaaagc tgaagccgac
     5821 aaggccggat tatctcccac agaattcacc gcccaggcgc tgaaatcggg cgatttacgt
     5881 atggcctgcg aacaacccga tagcggcagc aatcatccgc gtaatttgtt tgtctggcgt
     5941 tctaacctgc ttggttcctc cggcaaaggc cacgagtata tgcagaagta tctgctgggg
     6001 accgaaagcg ggattcaggg cgaggaactc ggtgccagcg acgggatcaa accggaagaa
     6061 gtcgagtggc aaactgcggc gattgaaggc aagctcgacc tgctggtgac gctcgacttc
     6121 cgtatgtcca gtacctgcct gttctccgat atcgttctgc ccaccgccac ctggtacgaa
     6181 aaagacgata tgaacacctc ggatatgcat ccgtttattc atccgctttc tgcggcggtc
     6241 gatccggcgt gggaatcacg cagcgactgg gaaatctaca aaggtatcgc caaagcattt
     6301 tcgcaactgt gcgtgggtca tcttggcaaa gaaaccgacg tggtattaca accactgcta
     6361 catgactctc cggcagaact ctcccagccg tgtgaagtgc tcgactggcg caaaggcgaa
     6421 tgcgatctga tcccgggtaa aaccgcgccc aatattgtgg cggtggaacg cgactaccct
     6481 gctacctatg aacgctttac ctcgctcggg ccattgatgg acaaacttgg caacggcggt
     6541 aaagggattt cgtggaatac ccaggatgaa atcgatttcc tcggcaaact caactacacc
     6601 aagcgtgaag gcccggcaca ggggcgtccg ctgattgaca ccgccattga cgcatcagaa
     6661 gtgattctgg cgctggcacc ggaaaccaac ggtcatgttg cagtcaaagc gtggcaggcg
     6721 ctgggcgaga tcaccggacg cgaacatacc catctggcgc tgcacaaaga ggacgagaag
     6781 attcgctttc gcgatattca ggcgcagcca cgtaaaatta tctccagccc cacatggtcc
     6841 ggtctggaaa gcgatcacgt ttcctataac gcgggataca ccaacgttca tgagttaatt
     6901 ccgtggcgca cgctgtcggg acgccagcag ctctatcagg atcatccgtg gatgcgtgct
     6961 tttggtgaaa gcctggtggc ttatcgcccg cctatcgaca cccgtagcgt cagtgaaatg
     7021 cgccagatac cgccaaacgg cttcccggaa aaagcactta acttcctgac gccgcaccag
     7081 aaatggggca ttcactcaac ctacagtgaa aacctgctaa tgctgacgct ctctcgcggt
     7141 ggaccaattg tctggatcag cgaaaccgat gcccgtgaac tgaccattgt cgataacgac
     7201 tgggtggaag tgtttaacgc caacggcgcg ctgacggccc gcgcggtggt cagccaacgt
     7261 gtaccgccgg gcatgaccat gatgtatcac gcccaggaac gcattatgaa tattcctggt
     7321 tcggaagtaa ctggcatgcg cggcggcatt cataactcgg tcacccgcgt ttgtccgaaa
     7381 ccaacgcata tgattggcgg ttacgcgcag ctggcctggg gctttaacta ctacggcacc
     7441 gtcggctcga accgcgacga attcatcatg atccgcaaga tgaagaacgt taactggctg
     7501 gatgatgaag gtcgcgatca ggttcaggag gcgaaaaaat gaaaatacgt tcgcaagtcg
     7561 gcatggtgct taacctcgat aaatgtatcg gctgccatac ctgttcggtg acctgtaaaa
     7621 acgtctggac cagacgcgaa ggcatggagt acgcatggtt taacaacgtc gaaaccaaac
     7681 cgggcattgg ttatccgaaa aactgggaag atcaggaaga gtggcaaggc ggctgggtgc
     7741 gtgatgtgaa tggcaagatc cgcccgcgtc tgggcagcaa gatgggcgtg attaccaaaa
     7801 tcttcgccaa cccggtggtg ccgcagattg atgattacta cgaacctttc accttcgact
     7861 acgaacattt gcatagcgcg ccagaaggta aacatattcc tactgcgcgc ccgcgttcac
     7921 tgattgacgg caaacggatg gacaaagtga tctgggggcc aaactgggaa gaattgttgg
     7981 gcggcgaatt tgaaaaacgc gcccgcgacc gcaacttcga ggccatgcaa aaggagatgt
     8041 acgggcagtt tgaaaacacg ttcatgatgt acctgccgcg cctgtgcgaa cactgcctca
     8101 atcccagctg cgtggcgacc tgcccaagcg gtgctatcta caaacgtgaa gaagacggca
     8161 ttgtgctgat tgatcaggat aaatgccgtg gctggcgttt gtgcattagc ggttgtccgt
     8221 acaaaaaaat ctacttcaac tggaaaagcg gcaagtcaga aaaatgcatc ttctgttacc
     8281 cacgaattga gtcaggccaa cccaccgtgt gctcagaaac ctgcgtgggt cgcatccgat
     8341 atctgggcgt gctgctttac gacgccgacc gcatcgagga agcggcgagc accgagcgcg
     8401 aagttgacct ctatgaacgc cagtgcgaag tgttcctcga tccgcacgat ccctcggtga
     8461 tcgaggaagc cctgaaacaa ggtattccac aaaacgtgat tgacgctgcc cagcgttcgc
     8521 cagtctacaa aatggcaatg gactggaaac tggcgctacc gctgcaccct gaataccgca
     8581 ctctgccgat ggtctggtac gttccgccgc tgtcaccgat tcagtcctac gctgatgcgg
     8641 gaggtttgcc gaaaagcgaa ggcgtgctgc ccgccatcga aagcctgcgt attccggtgc
     8701 aatatctcgc caatatgttg agtgccggtg ataccggtcc ggtactgcgg gcgctgaaac
     8761 ggatgatggc gatgcgccac tatatgcgtt cacaaaccgt ggaaggcgtt actgatactc
     8821 gtgccatcga cgaagtaggt ctgagcgtcg cccaggtcga agagatgtat cgttacctcg
     8881 ccattgccaa ctatgaagac cgttttgtca tcccgacaag ccatcgggaa atggcgggcg
     8941 atgccttcgc agaacgcaac ggctgcggtt ttacctttgg cgacggttgc cacggctcgg
     9001 acagcaaatt caacctgttc aacagtagcc gtatcgatgc catcaacatc accgaagtgc
     9061 gcgacaaagc ggagggcgaa taatgcagat cctcaaagtg atcggcctgt tgatggagta
     9121 tccggacgag ctgttgtggg aatgtaagga ggacgcgctg gcgttgatcc gccgcgacgc
     9181 accgatgctt acggatttta cccgcaacct gcttaacgcg ccgctgctgg ataaacaggc
     9241 cgaatggtgc gaagtgtttg accgtggacg taccacatcg ctgctgctgt tcgaacatgt
     9301 tcatgccgag tcccgcgatc gcggccaggc aatggtggac ctgctggcgg agtatgaaaa
     9361 ggtcggtctg cagttggatt gtcgagaact gcccgattat ctgccgctgt atctggagta
     9421 cttaagcgta ctgccggacg atcaggcgaa agaaggcttg ctcaacgttg cgccgatcct
     9481 cgccctgctt ggcggacgct taaaacaacg cgaggcaccg tggtacgcgt tatttgacac
     9541 cctgttgcaa ctggcaggaa gccctctgtc aagtgacagc gtcacaaaac agattcgcag
     9601 tgaagagcgt gacgacaccc gccaggcgct ggatgcggtg tgggaagaag aacaggtgaa
     9661 gtttattgaa gataacgcca cggcgtgtga cagctcgccg cttaatcaat atcagcgacg
     9721 ctttagccag gatgtcgcgc cgcagtatgt cgacatcagt gcgggaggtg ggaaatgatt
     9781 cagtatctga acgtcttttt ttacgatatc tacccgtact tgtgtggcac ggtttttatc
     9841 cttggaagct ggctgcgcta cgattacggg cagtatacct ggcgcgccgc ctccagccag
     9901 atgctggata aacgtggtat ggtgctgtgg tcgaatctgt tccatatcgg cattttgggg
     9961 attttcttcg ggcacctgtt cggcatgtta acgccgcact ggatgtacgc gtggtttttg
    10021 ccagtggcag cgaaacaact aatggcgatg atcctcggcg gaatatgcgg ggtattgacg
    10081 ctgattggcg gtgcggggct actggtgcgt cgtttaacaa atccgcgtat cagggcgacg
    10141 tcttctggtg cggatatcct gatcctcgct attttgttaa ttcagtgcat tcttgggtta
    10201 accaccattc ctttttcagc acaacatccg gacggcagtg aaatgatgaa gctggtgggc
    10261 tgggcgcaaa gcattgtcac tttccagggc ggtgcatcta cgcatcttga tggtgtcgcc
    10321 tttatattcc gcgttcatct ggtgcttgga atgaccatct ttctgctctt cccgttcacc
    10381 cgactggtgc atgtctggag cgcgccgttt gagtacttta ctcgtcggta tcagattgtg
    10441 cgttcgcggc gttaattctc tcgcgggccg gatagctctt cgctctccgg ccacttgcag
    10501 gctatgatag ttctccagcc acaggagaac attaatgaaa ccgcaggttt accacgtcga
    10561 tgcttttacc tctcaaccgt ttcgcggcaa ttctgccggt gttgttttcc ccgccgataa
    10621 tcttagcgaa gcgcaaatgc agcttatcgc ccgcgagtta ggtcattcgg aaactgcttt
    10681 tctgctgcac agcgacgaca gcgatgtgcg catccgctac tttacgccaa cggttgaagt
    10741 tccgatttgt ggtcacgcga cagtagctgc gcactatgta cgtgcaaagg tgttaggttt
    10801 aggaaattgc accgtctggc aaacgtcgct ggcaggaaaa catcgtgtga ctatcgaaaa
    10861 gcaaaatgat gattatcgta tttcgctgga acaaggtact ccaggctttg agccaccgct
    10921 gaaaggtgaa acacgtgcag cgattatcaa cgcgcttcat ctcactgaag acgatatttt
    10981 gcaaggcttg ccaatccagg tggctaccac aggacactca aaagtgatga ttccactgaa
    11041 gccggaagtg gatatcgacg ccctttcgcc tgaccttgct gcgctgacca caatcagcaa
    11101 acagattggc tgcaatggtt tcttcccgtt ccagatccgc ccaggcaaaa acgaaaccga
    11161 tggtcgcatg ttctcgcctg cgattggtat tgtggaagat ccggtgactg gcaatgccaa
    11221 tggcccgatg ggtgcatggt tagtacatca caacgtattg ccacacgatg gcaacgtgtt
    11281 gcgtgttaaa ggccatcagg ggcgcgcatt agggcgtgaa ggcgtgattg aagtgacggt
    11341 gacaattcgt gataaccaac cggagaaagt caccatttct ggcacggcgg tgattttgtt
    11401 tcatgccgaa tgggcaattg aactctgaaa ccgttgcctg atgcgcttcg cttatcaggc
    11461 ctacaaccgg actaatgtat gccggattag gcatttacgc cacatccggc aacctgacat
    11521 aaattatttt cccgcctccg ggtgcgtatc aaacgccgcc atcaccagcg ctaactcatc
    11581 cacagtaaag ccatgtttcg catcatctac gcccagacca aactgttcct gcatcacggc
    11641 atataacgac gccacatctg gtagatttcg ctgcttaact gcgtgcccat tttcataatg
    11701 ggtaaaatga aaattggtca gtgtcagctt gccaccgtcc ggcaaatggc gacacatcag
    11761 caaatgatgg cgaaaatgcg actgcggcca atgcgccgac cagaaattgc ccatcacata
    11821 atcgctttgt tgctgctcgc agagatcaaa acggtacatc gactgccagt gctgatgatg
    11881 attaaactgc aacacccaat catcaccctc ttgcaacaac cgatactctc cgtgtggcgt
    11941 ggtttgcatg atatccggca ttaaacgaat cggcgcggtt agcgtctgcc caccgaaacc
    12001 gacatcagca atccattttt ccccttccag ttccaccaac agcaaacgat gggtgcgcgg
    12061 cggtaatgct ggcggatttg ataacactac gcgccctaac aagctgcgaa cgttaaaccc
    12121 cagctcgcgt aacacacgct caaacacgcc attctgctca aaacagtaac cgccacgacg
    12181 ggctatcacc agtttctctt ccagcgattg atcatcaagc tgtatttccc tcggcagcaa
    12241 aacgtcgaga ttttcaaacg gaatggtgca attgtgtttc aggtgcaatg cacgcagcgt
    12301 atcaatattg gccgcagcag ctcccaacca gttaatacgg gcaaaatagt gattcagaat
    12361 gggcgtcatc aggcgtttcc cttagtggtt ttctcaactt ataacctgga atagacgccg
    12421 cactggctat tttgtgcgat cgcggacatg catcacgttc gcaaatcgcc aatcccgtta
    12481 atttcgttac ttattgcgtt acgagctacg cttttaaaac acccttcata gcgaggcgat
    12541 atcgtgagcc aattcattcc cgtcgaatta caccatgcca gccgtctgtt aaatcatggc
    12601 ccaactgtca tgatcaccag tttcgatgag caatcccagc ggcgtaacat tatggcagca
    12661 gcctggtcta tgcccgtaga gtttgaaccg ccacgcgtgg cgattgtggt agataaatcg
    12721 acatggacca gggagttgat tgagcgtaac ggtaaatttg gcatcgttat cccaggcgtt
    12781 gcggcgacta actggacgtg ggcggtggga agtgtgtcgg ggcgtgatga agataagttt
    12841 aactgctatg gtattccggt tgtgaaaggt ccggtgcttg gtttgccgct ggtcgaggaa
    12901 aaatgtctgg cgtggatgga gtgtcgcctg ctacctgcga cttctgcgca agaaaaatac
    12961 gacacgctgt ttggcgaagt ggtatcagca gcggcagacg cacgggtatt tgtcgaaggc
    13021 cgctggcagt ttgatgatga taagctcaat acgttgcatc atttaggcgc tggcacgttt
    13081 gttaccagcg gcaagcgtgt tacggcaggt taagcattac atgctgtaac caggtttctt
    13141 tatcagcgtc tccatttggg gcgcaatttc ggcgtcccag atagcttgcc atgattctgg
    13201 ttgaatctgc tgtagagcaa tgcttatcga actgtcttta ctgttcagat ggcgaataat
    13261 aacgtcggta atatctgcag caagtgctgc tttttgttgt tcgtccagtt cacgtggaaa
    13321 acatttaatg tctatgtgcg gcatgattgt gctccttttg aaagatgtca gtaaaattaa
    13381 cacacgttgt gaatgttatg tgtccggtga tgctttttta cggcaataat gcctacttga
    13441 atttgtacag gtttgtacta caccctttta aataaagcgc caacaaaaac gtcaacttgc
    13501 agaatatatt cttcgccaac atgccattaa gaaaacatca agttcccggc ttgccaattt
    13561 attaacgccc attatagtta ttcttgccct cacaaaaatt ttcatccgta attaccccca
    13621 ataaaagtcc attctggaga cgcttaagat gcagcttaat catattgtta aaagtctgct
    13681 aataacggga ttattcacca ccagttcttt gccactccag ggaaagatta cgaaagcccg
    13741 ctccccgcaa ggactgacgc cagatagttt ctgtccatga ctgcttttcg catcttacgt
    13801 cttaaccctg ccttgaatac cttatcattc gtcaaaatat caatagcgat gtgccgtatc
    13861 cctgaaaata
//
LOCUS       DADXDL010000112        13841 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.112, whole genome shotgun sequence.
ACCESSION   DADXDL010000112 DADXDL010000000
VERSION     DADXDL010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13841)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13841)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13841
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.112"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..763)
                     /locus_tag="IRB70_004138"
     CDS             complement(<1..763)
                     /locus_tag="IRB70_004138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SopA family protein"
                     /protein_id="HBC0633983.1"
                     /translation="MIGHITNSGGNDSLMKHDVVQGNNKLDLDLLRNFNGVPGLNRDN
                     FIYISDIFLNIKQRNEKNHAINMFREVSISNDIISVKFYRNEEIECACDFLMDKDAQG
                     YTDLSDLDLTSCHFKGDVISKVSFISSNLQHVTFECKEIGDCNFTTATVDNVIFKCRR
                     LHNVIFIKATGEYVDFSQSILDTVDFSRSQLTHSNFRECQIRNSKFNNCYLYASHFTR
                     AEFLSDKEISFIKSNLTAVMFDHVRISTGNFKDSVT"
     gene            complement(991..1911)
                     /gene="malM"
                     /locus_tag="IRB70_004139"
     CDS             complement(991..1911)
                     /gene="malM"
                     /locus_tag="IRB70_004139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose operon protein MalM"
                     /protein_id="HBC0633984.1"
                     /translation="MKMNKSLIALCLSAGLLASAPGISLADVNYVPQNTSDAPAIPSA
                     ALQQLTWTPVDQSKTQTTQLATGGQQLNVPGISGPVAAYSVPANIGELTLTLTSEVNK
                     QTSVFAPNVLILDQNMTPSAFFPSSYFTYQEPGVMSADRLEGVMRLTPALGQQKLYVL
                     VFTTEKDLQQTTQLLDPAKAYAKGVGNSIPDIPDPVARHTTDGLLKLKVKTNSSSSVL
                     VGPLFGSSAPAPVTVGNTAAPAVAAPAPAPVKKSEPMLNDTESYFNTAIKNAVAKGDV
                     DKALKLLDEAERLGSTSARSTFISSVKGKG"
     gene            complement(2154..3494)
                     /gene="lamB"
                     /locus_tag="IRB70_004140"
     CDS             complement(2154..3494)
                     /gene="lamB"
                     /locus_tag="IRB70_004140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltoporin LamB"
                     /protein_id="HBC0633985.1"
                     /translation="MMITLRKLPLAVAVAAGVMSAQAMAVDFHGYARSGIGWTGSGGE
                     QQCFQTTGAQSKYRLGNECETYAELKLGQEVWKEGDKSFYFDTNVAYSVAQQNDWEAT
                     DPAFREANVQGKNLIEWLPGSTIWAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVG
                     FGKLSLAATRSSEAGGSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDY
                     GRANLRDNYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGSG
                     VAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDNDNGTKWWTVG
                     IRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQWQAGDSIWSRPAIRVFA
                     TYAKWDEKWGYDYTGNANTNTNFGKAVPADFNGGSFGRGDSDEWTFGAQMEIWW"
     gene            complement(3566..4681)
                     /gene="malK"
                     /locus_tag="IRB70_004141"
     CDS             complement(3566..4681)
                     /gene="malK"
                     /locus_tag="IRB70_004141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011915502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter ATP-binding
                     protein MalK"
                     /protein_id="HBC0633986.1"
                     /translation="MASVQLQNVTKAWGEVVVSKDINLDIHEGEFVVFVGPSGCGKST
                     LLRMIAGLETITSGDLFIGEKRMNDTPPAERGVGMVFQSYALYPHLSVAENMSFGLKL
                     AGAKKEVINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSVFLLDEP
                     LSNLDAALRVQMRIEISRLHKRLGRTMIYVTHDQVEAMTLADKIVVLDAGRVAQVGKP
                     LELYHYPADRFVAGFIGSPKMNFLPVKVTATAIDQVQVELPMPNRQQVWLPVESRDVQ
                     VGANMSLGIRPEHLLPSDIADVILEGEVQVVEQLGNETQIHIQIPSIRQNLVYRQNDV
                     VLVEEGATFAIGLPPERCHLFREDGTACRRLHKEPGV"
     gene            5046..6236
                     /gene="malE"
                     /locus_tag="IRB70_004142"
     CDS             5046..6236
                     /gene="malE"
                     /locus_tag="IRB70_004142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000695396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose/maltodextrin ABC transporter
                     substrate-binding protein MalE"
                     /protein_id="HBC0633987.1"
                     /translation="MKIKTGARILALSALTTMMFSASALAKIEEGKLVIWINGDKGYN
                     GLAEVGKKFEKDTGIKVTVEHPDKLEEKFPQVAATGDGPDIIFWAHDRFGGYAQSGLL
                     AEITPDKAFQDKLYPFTWDAVRYNGKLIAYPIAVEALSLIYNKDLLPNPPKTWEEIPA
                     LDKELKAKGKSALMFNLQEPYFTWPLIAADGGYAFKYENGKYDIKDVGVDNAGAKAGL
                     TFLVDLIKNKHMNADTDYSIAEAAFNKGETAMTINGPWAWSNIDTSKVNYGVTVLPTF
                     KGQPSKPFVGVLSAGINAASPNKELAKEFLENYLLTDEGLEAVNKDKPLGAVALKSYQ
                     DELAKDPRIAATMDNAQKGEIMPNIPQMSAFWYAVRTAVINAASGRQTVDAALKDAQT
                     RITK"
     gene            6390..7934
                     /gene="malF"
                     /locus_tag="IRB70_004143"
     CDS             6390..7934
                     /gene="malF"
                     /locus_tag="IRB70_004143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalF"
                     /protein_id="HBC0633988.1"
                     /translation="MDVIKKKHWWQSDALKWSVLGLLGLLVGYLVVLMYAQGEYLFAI
                     TTLILSSAGLYIFANRKAYAWRYVYPGMAGMGLFVLFPLVCTIAIAFTNYSSTNQLTF
                     ERAQEVLLDRSWQAGKTYNFGLYPAGDEWQLALSDGETGKNYLSDAFKFGGEQKLQLK
                     ETAAQPEGERANLRVITQNRQALSDITAILPDGNKVMMSSLRQFSGTQPLYTLDGAGT
                     LTNNQSGVKYRPNNQIGFYQSITADGNWGDEKLSPGYTVTTGWKNFTRVFTDEGIQKP
                     FLAIFVWTVVFSLITVFLTVAVGMVLACLVQWEALRGKAVYRVLLILPYAVPSFISIL
                     IFKGLFNQSFGEINMMLSALFGVKPAWFSDPTTARTMLIIVNTWLGYPYMMILCMGLL
                     KAIPDDLYEASAMDGAGPFQNFFKITLPLLIKPLTPLMIASFAFNFNNFVLIQLLTNG
                     GPDRLGTTTPAGYTDLLVNYTYRIAFEGGGGQDFGLAAAIATLIFLLVGALAIVNLKA
                     TRMKFD"
     gene            7949..8839
                     /gene="malG"
                     /locus_tag="IRB70_004144"
     CDS             7949..8839
                     /gene="malG"
                     /locus_tag="IRB70_004144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001252048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose ABC transporter permease MalG"
                     /protein_id="HBC0633989.1"
                     /translation="MAMVQPKSQKARLFITHLLLLLFIAAIMFPLLMVVAISLRQGNF
                     ATGSLIPEQISWDHWKLALGFSVEQADGRITPPPFPVLLWLWNSVKVAGISAIGIVAL
                     STTCAYAFARMRFPGKATLLKGMLIFQMFPAVLSLVALYALFDRLGEYIPFIGLNTHG
                     GVIFAYLGGIALHVWTIKGYFETIDSSLEEAAALDGATPWQAFRLVLLPLSVPILAVV
                     FILSFIAAITEVPVASLLLRDVNSYTLAVGMQQYLNPQNYLWGDFAAAAVMSALPITI
                     VFLLAQRWLVNGLTAGGVKG"
     gene            complement(8933..9343)
                     /gene="psiE"
                     /locus_tag="IRB70_004145"
     CDS             complement(8933..9343)
                     /gene="psiE"
                     /locus_tag="IRB70_004145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate-starvation-inducible protein PsiE"
                     /protein_id="HBC0633990.1"
                     /translation="MTSLSRPRVEFISTILQTVLNLGLLCLGLILVVFLGKETVHLAD
                     VLFAPEQTSKYELVEGLVVYFLYFEFIALIVKYFQSGFHFPLRYFVYIGITAIVRLII
                     VDHKSPLDVLIYSAAILLLVITLWLCNSKRLKRE"
     gene            9557..9835
                     /locus_tag="IRB70_004146"
     CDS             9557..9835
                     /locus_tag="IRB70_004146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633991.1"
                     /translation="MKRNLIKVVKMKPYFAALMLSVSVLPAYAGPLGTADKADLPQSN
                     VSSPMMAQSLRQPDLQPISTDRKTECFRLYTPDRKPGVNCVPDGSTGH"
     gene            complement(9882..11978)
                     /locus_tag="IRB70_004147"
     CDS             complement(9882..11978)
                     /locus_tag="IRB70_004147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbH domain-containing protein"
                     /protein_id="HBC0633992.1"
                     /translation="MKKRHLLSLLALGISTACYGETYPAPIGPSQSDFGGVGLLQTPT
                     ARMAREGELSLNYRDNDQYRYYAASVQLFPWLETTLRYTDVRTRQYSSVEAFSGDQTY
                     KDKAFDLKLRLWEESYWLPQVAVGARDIGGTGLFDAEYLVASKAWGPFDFTLGLGWGY
                     LGTSGNVKNPLCSASDKYCYRDNSYKQAGSIDGSQMFHGPASLFGGVEYQTPWQPLRL
                     KLEYEGNNYQQDFAGKLEQKSKFNVGAIYRVTDWADVNLSYERGNTFMFGVTLRTNFN
                     DLRPSYNDNARPQYQPQPQDAILQHSVVANQLTLLKYNAGLADPQIQTKGDTLYVTGE
                     QVKYRDSREGIIRANRIVMNDLPDGIKTIRITENRLNMPQVTTETDVASLKNHLAGEP
                     LGHETKLAQKRVEPVVPQSTEQGWYIDKSRFDFHIDPVLNQSVGGPENFYMYQLGVMG
                     TADLWLTDHLLTTGSLFANLANNYDKFNYTNPPQDSHLPRVRTHVREYVQNDVYVNNL
                     QANYFQHLGNGFYGQVYGGYLETMFGGAGAEVLYRPLDSNWAFGVDANYVKQRDWRSA
                     KDMMKFTDYSVKTGHLTAYWTPSFAQDVLVKASVGQYLAGDKGGTLEIAKRFDSGVVV
                     GGYATITNVSKEEYGEGDFTKGVYVSVPLDLFSSGPTRSRAAIGWTPLTRDGGQQLGR
                     KFQLYDMTSDRSVNFR"
     gene            complement(11978..12715)
                     /locus_tag="IRB70_004148"
     CDS             complement(11978..12715)
                     /locus_tag="IRB70_004148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule biosynthesis GfcC family protein"
                     /protein_id="HBC0633993.1"
                     /translation="MIKQTIVALILSVGASSVFAAGTVKVFSNGSSEAKTLTGAEHLI
                     DLVGQPQLANSWWPGAVISEELATAAALRQQQALLTRLAELTADSSADDAAAINALRQ
                     QIQALKVTGRQKINLDPDIVRVAERGNPPLQGNYTLWVGPPPSTVTLFGLISRPGKQS
                     FTPGRDVTSYLSDQSLLSGADRSYAWVVYPDGRTQKAPVAYWNKRHVEPMPGSIIYVG
                     LADSVWSETSDALNADILQTLTQRIPQ"
     gene            complement(12712..13350)
                     /locus_tag="IRB70_004149"
     CDS             complement(12712..13350)
                     /locus_tag="IRB70_004149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418451.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbF family lipoprotein"
                     /protein_id="HBC0633994.1"
                     /translation="MKRPALILICLLLQACSATTKELGNSLWDSLFGTPGVQLTDDDI
                     QNMPYASQYMQLNGGPQLFVVLAFAEDGQQKWVTQDQATLVTQHGRLVKTLLGGDNLI
                     EVNNLAADPLIKPAQIVDGATWTRTMGWTEYQQVRYATARSVFKWDGTDTVKVGSDET
                     PVRVLDEEVSTDQARWHNRYWIDSEGQIRQSEQYLGADYFPVKTTLIKAAKQ"
     gene            complement(13464..13706)
                     /locus_tag="IRB70_004150"
     CDS             complement(13464..13706)
                     /locus_tag="IRB70_004150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0633995.1"
                     /translation="MKKVLYGIFAISALAATSAWAAPVQVGEAAGSAATSVSAGSSSA
                     TSVSTVSSAVGVALAATGGGDGSNTGTTTTTTTSTQ"
BASE COUNT         3308 a         3611 c         3510 g         3412 t
ORIGIN      
        1 gtgtaacgct gtctttaaaa ttccctgtcg atattcgcac atgatcaaac ataacagctg
       61 tcaaattcga tttaataaat gatatttctt tgtcagaaag aaattctgct ctggtgaagt
      121 gcgaagcata aagataacaa ttattgaact ttgaatttct aatctgacat tcacgaaaat
      181 tactatgagt aagctggctc cgcgagaagt caactgtatc aagaatactt tggctaaaat
      241 cgacatattc gccagtcgct ttgataaaaa tcacattgtg taaacgtcga catttaaata
      301 tgacattatc aactgttgca gtagtaaaat tgcaatcccc tatttcttta cattcgaatg
      361 ttacatgttg tagatttgat gatatgaaag acaccttcga aataacgtca cctttaaaat
      421 gacaacttgt taaatccaaa tcagacaggt cagtataccc ctgcgcatct ttatccatca
      481 gaaaatcaca agcacattct atttcttcat ttctataaaa ttttacgctt ataatatcat
      541 tactgattga gacttcacga aacatattta ttgcatgatt tttttcgttc cgttgtttta
      601 tatttaaaaa tatatcactg atataaataa agttatctct atttaaacct ggcaccccat
      661 taaaattacg tagtaaatca agatctaatt tattatttcc ttgcaccaca tcatgtttca
      721 tcaaagagtc attgccgcca gaatttgtga tatgacctat cataaaacct ctgtattaca
      781 gaaatgaaat tactggaaaa gtagcctgag cgtccagaca ctaccggcga aaggaaaaga
      841 atctctgata aggcattgag ataatggata ttcttagtga agaagaagcg aagtactata
      901 aaaaatcgct catatcccag gaatgaagca taaaaaaagg tgcgccagga gacgcaccag
      961 ttgttgcaaa atcagcactg tggggcgtaa ttaccccttg ccttttacac tgctgataaa
     1021 ggtggaacgg gcagatgttg accccaggcg ttcagcttca tcaagcagtt ttaacgcctt
     1081 atcaacatca cctttcgcga cagcgttttt gatcgcggta ttaaaataac tttccgtgtc
     1141 gttgagcatc ggctcgcttt tcttcaccgg tgccggagcg ggtgcagcca cagctggtgc
     1201 cgccgtgttg cctaccgtaa ccggagctgg agcggaagaa ccaaatagtg gtcctaccaa
     1261 cacgctggag ctggagttcg ttttcacttt cagtttcagt aagccatcgg tggtatgacg
     1321 agcaaccgga tcgggaatat ccgggatcga gttaccgacg cctttggcat aggctttagc
     1381 cgggtcgagc agttgagtcg tctgctggag atctttttcc gtggtaaaga ccagaacata
     1441 aagtttttgc tgccccaacg ctggtgtcag gcgcataacg ccttccagcc gatctgcact
     1501 catcacgcct ggttcctggt aggtgaaata actgctgggg aagaaggctg atggggtcat
     1561 gttctgatca agaatcagca cgttcggcgc aaatacgctg gtttgtttgt tcacttcgct
     1621 ggtcagcgtc agtgtcagtt cgccaatgtt tgccgggacg ctgtacgcag caaccggacc
     1681 actgatgccg gggacgttca gttgttggcc gccggtcgcc agttgggtgg tctgggtttt
     1741 agattgatcg accggtgtcc aggtgagttg ttgcagcgcg gcagatggaa tggctggcgc
     1801 gtcgctggtg ttttgcggta cgtagttaac atcggcaagg ctgattccag gcgcgcttgc
     1861 cagtaaccct gctgataaac agagggcgat gagactttta ttcattttca ttgttttcac
     1921 ctcaaaatct ggagctcagc ggtagccagg caatagcgcg ctaaacccga taatcagagg
     1981 ggcttgcgcc cctttcagat aatgacaacc tgtttttatg ccggatgcgg cgtaaacgcc
     2041 ttatccggcc tacatttgac agccgttgta ggcctgataa gacgcgcaag cgtcgcatca
     2101 ggcgttggtt gccggatgcg gcgcaagcac cttatccggc ccaggttttg ctattaccac
     2161 cagatttcca tctgggcacc gaaggtccac tcgtcgctgt caccacggcc gaagctgccg
     2221 ccgttgaaat cagcaggaac ggctttgccg aagttagtgt tggtattggc gttaccggtg
     2281 tagtcgtaac cccatttctc atcccacttg gcgtaggttg cgaagacacg aatagccggg
     2341 cgtgaccaga tgctgtcgcc agcctgccat tgttgtgcaa gggtaatttt gtactgattg
     2401 ttcttgtcgc cggtgcgctg ggattcgacg ttgtcgtagc cgatttccat cacggtgctc
     2461 atgattggcg tccacttgta catcgggcga ataccgacgg tccaccactt ggtgccgttg
     2521 tcgttatccc agttgatatc ctggtacata cccacgtaca tcatgtccca gttatcgccc
     2581 atggagatcg caccgtggtc gaggatacgc agcatgtgac cgttgttgtt gatattgtag
     2641 gcaaattttt cgttatcaaa cgcgacgcca gaaccctgcg acagaccttt accctgtgag
     2701 gtcatcgagt cagtagcgta ctgaacaaca aacttgttaa agcccttcag gacactctga
     2761 gtatgttcag cagtgaataa ccaaccgtct ttcgatgcgc catcaaccag acgatagtta
     2821 tcacgcaggt tggcacgacc gtagtcgaca cccagttcta atgtgccgcc cgggttgatt
     2881 tccatctgcg ctaaacgcac gtcgaaaacg tcgttcgcgg tttcgttggt atagtcataa
     2941 atattgttgc tggcgaaaga ggaagaacca ccagcttcag aggagcgggt tgctgccaga
     3001 gagagtttac cgaagccaac atcgatgttt tccagaccgg caccaggacc agaaatatcc
     3061 cagtagtaga agtcgatcat atgaacgtca tgacgttggt agaagcgctt acctgcccag
     3121 atggtggagc ctggcagcca ttcgatcagg tttttaccct gcacgtttgc ttcacggaag
     3181 gccggatcgg tagcttccca gtcattctgt tgtgcgacgg aataggccac gttagtgtcg
     3241 aaatagaagc tcttatcgcc ctctttccac acttcctgac ccaattttaa ttcagcataa
     3301 gtttcacatt cgttgccaag acggtattta ctttgagcac cggtagtctg gaaacactgt
     3361 tgttcaccgc cgctacctgt ccagccaata ccggaacgtg catagccgtg gaaatcaaca
     3421 gccattgcct gagcagacat tacgcccgct gcgacggcaa ccgccagagg aagtttgcgc
     3481 agagtaatca tcattctatc tcctgagtca ttgcttttct tttttcacat cacctgtgac
     3541 aggctttgtg tgttttgtgg ggtgcttaaa cgcccggctc cttatgcagt cgacgacatg
     3601 cagtgccatc ctcacggaac agatggcaac gctctggcgg caggccgata gcgaatgtgg
     3661 caccttcttc taccaacacc acgtcgttct ggcggtacac caggttttga cgaatggaag
     3721 ggatctggat atggatttgc gtttcgttgc cgagttgctc gacgacctga acttcaccct
     3781 caaggatgac gtcagcgata tcactcggca gtagatgttc cgggcgaata cccagtgaca
     3841 tattggctcc aacctggaca tcacggcttt cgaccggtag ccagacttgc tgacgattcg
     3901 gcatcggcag ctccacctgc acttgatcga ttgcggtggc ggtcactttt actggcagga
     3961 agttcatctt tggagaaccg ataaatccgg cgacaaaacg gtctgccgga tagtgataca
     4021 gctccagcgg tttcccaacc tgcgccacgc gaccagcgtc cagcaccacg attttgtcgg
     4081 ccagcgtcat cgcttcgacc tgatcgtggg tgacgtaaat cattgtgcgg cccaggcgtt
     4141 tatgcagacg ggagatttcg atacgcattt gcacacgcag tgcagcatcg aggttggaga
     4201 gcggttcatc gagcaaaaat acgcttggct cggccaccag cgtacggcca atcgccacac
     4261 gctgacgctg accaccggag agcgctttcg gtttgcgatc cagcaaatgc gccagttgca
     4321 gcacttccgc aacctggtta actcgctggt taatcacttc ttttttcgcg ccagccagtt
     4381 tcaggccaaa tgacatgttt tctgctactg acaggtgggg atagagcgcg taagactgaa
     4441 acaccatacc aacgccgcgt tctgcaggcg gagtgtcatt catccgtttc tcaccgatga
     4501 acaggtcgcc gctggtgatc gtctcaagcc cggcaatcat gcgcagtaaa gtcgatttac
     4561 cgcagccaga cggtccgaca aacaccacga attcaccttc atggatatcg agattgatat
     4621 ctttcgatac cacgacctcg ccccaggctt tcgttacatt ttgcagctgt acgctcgcca
     4681 tgcccttctc cctttgtaac aacctgtcat cgacagcaac attcatgatg ggctgactat
     4741 gcgtcatcag gagatggctt aaatcctcca ccccctggct tttttatggg ggaggaggcg
     4801 ggaggatgag aacgcagctt ctgtgaacta aaccgaggtc atgtaaggaa tttcgtgatg
     4861 ttgcttgcaa aaatcatggc gattttatgt gcgcatctcc acattaccgc caattctgta
     4921 acagagatca cacaaagcaa cgatggggcg taggggcaag gaggatggaa agaggttgcc
     4981 gtataaagaa actagagtcc gtttaggtgt tttcacgagc acttcaccaa caaggaccat
     5041 agattatgaa aataaaaaca ggtgcacgca tcctcgcatt atccgcatta acgacgatga
     5101 tgttttccgc ctcggctctc gccaaaatcg aagaaggtaa actggtaatc tggattaacg
     5161 gcgataaagg ctataacggt ctcgctgaag tcggtaagaa attcgagaaa gataccggaa
     5221 ttaaagtcac cgttgagcat ccggataaac tggaagagaa attccctcag gttgcggcaa
     5281 ctggcgatgg ccctgacatt atcttctggg cgcacgaccg ctttggtggc tacgctcaat
     5341 ctggcctgtt ggctgaaatc accccggaca aagcgttcca ggacaagctg tatccgttta
     5401 cctgggatgc cgtacgttac aacggcaagc tgattgctta cccgatcgct gtcgaagcgt
     5461 tatcactgat ttataacaaa gatctgctac cgaacccgcc aaaaacctgg gaagagatcc
     5521 cggcgctgga taaagaactg aaagcgaaag gtaagagcgc gctgatgttc aacctgcaag
     5581 aaccatactt cacctggccg ctaattgcgg ctgacggggg ttatgcgttc aagtatgaaa
     5641 acggcaagta cgacattaaa gacgtaggcg tggataacgc tggcgcgaaa gcgggtctga
     5701 ccttcctggt tgatctgatt aaaaacaaac acatgaatgc agacaccgat tactccatcg
     5761 cagaagctgc ctttaataaa ggcgaaacag cgatgactat caacggcccg tgggcatggt
     5821 ccaacatcga caccagtaaa gtgaattatg gtgtaacggt actgccaacc ttcaaaggtc
     5881 aaccatctaa accgttcgtt ggcgtgctga gcgcaggtat taacgccgcc agtccgaaca
     5941 aagagctggc gaaagagttc ctcgaaaact atctgctgac tgacgaaggt ctggaagcgg
     6001 tcaataaaga caaaccgctg ggtgcagtag cgctgaagtc ctatcaggat gaacttgcga
     6061 aagatccacg tattgccgcc accatggata acgctcagaa aggtgaaatt atgccgaaca
     6121 tcccgcagat gtccgctttc tggtatgccg tgcgtactgc ggtgatcaac gccgccagcg
     6181 gtcgtcagac tgtggatgct gcgctgaaag atgcacagac tcgtatcacc aagtaatgct
     6241 gtgaaatgcc ggatgcggcg taaacgcctt atccggccta cgaaattgaa acgtatgtag
     6301 gcctgataag acgcgtcagc gtcgcatcag gcagttgttg tcggataagg tatgaaagcc
     6361 ttatccgtcc tggaatgagg aagaacccca tggatgtcat taaaaagaaa cattggtggc
     6421 aaagcgacgc gctgaaatgg tcagtgttag gtctgctcgg cctgctggtg ggttaccttg
     6481 ttgttttaat gtacgcacaa ggggaatacc tgttcgccat taccacgctg atattgagtt
     6541 cagcggggct gtatattttc gccaatcgta aagcctacgc ctggcgctat gtttacccgg
     6601 gaatggctgg aatgggatta ttcgtcctct tccctctggt ctgcaccatc gccattgcct
     6661 tcaccaacta cagcagcact aaccagctga cttttgaacg tgcacaggaa gtgttgttag
     6721 atcgctcctg gcaagcaggc aaaacctata actttggtct ttacccggcg ggcgatgagt
     6781 ggcaactggc gctcagcgac ggcgaaaccg gcaaaaatta tctctccgac gcgtttaaat
     6841 ttggcggcga gcaaaaactg caactgaaag aaacggccgc ccagcctgaa ggcgaacgcg
     6901 cgaatctccg cgtgattacc cagaatcgtc aggcgctgag tgacattacc gccattctgc
     6961 cggatggcaa caaagtgatg atgagctccc tgcgccagtt ttctggcacg cagccgctct
     7021 acacactcga cggtgccggc acgttgacga ataatcagag cggcgtgaaa tatcgtccga
     7081 ataaccaaat tggcttttac cagtccatta ccgccgacgg caactggggc gatgaaaagc
     7141 taagccccgg ttacaccgtg accactggct ggaaaaactt tacccgcgtc ttcaccgacg
     7201 aaggcattca gaaaccgttc ctcgccattt tcgtctggac cgtggtgttc tcgctgatca
     7261 ctgtcttttt aacggtggcg gtcggcatgg ttctggcgtg tctggtgcag tgggaagcgt
     7321 tgcgcggaaa agcggtctat cgtgtcctgc tgattctgcc ctatgcggtg ccatcgttca
     7381 tttcaatctt gattttcaaa gggttgttta accagagctt cggtgagatc aacatgatgt
     7441 tgagcgcgct gtttggcgtg aagcccgcct ggttcagcga tccgaccacc gcccgaacga
     7501 tgctgattat cgtcaatacc tggctgggtt atccgtacat gatgatcctc tgcatgggct
     7561 tgctgaaagc gattccggac gatttgtatg aagcctcagc aatggatggc gcaggtccgt
     7621 tccagaactt ctttaagatt acgctgccgc tgcttattaa accgctgacg ccgctgatga
     7681 tcgccagctt cgcctttaac tttaacaact tcgtgctgat tcaactgtta accaacggcg
     7741 gcccggatcg tcttggcacg accacgccag ccggttatac cgacctgctt gttaactaca
     7801 cctaccgcat cgcttttgaa ggcggcgggg gtcaggactt cggtctggca gcagcaattg
     7861 ccacgctgat cttcctgctg gtgggcgcgc tggcgatagt gaacctgaaa gccacgcgaa
     7921 tgaagtttga ttaagggaga taacaaaaat ggcaatggtc caaccgaaat cgcaaaaagc
     7981 acgtttgttt attactcacc tgctactgct actttttatc gcggcaatta tgttcccgct
     8041 gctgatggtc gtcgccatct cgctgcgtca ggggaacttc gcgaccggta gtctgatccc
     8101 ggagcaaatc tcctgggatc actggaaact ggcgttaggt tttagtgtgg aacaggctga
     8161 tggtcgcatt acgccaccgc cattcccggt actgctgtgg ctgtggaact cggtaaaggt
     8221 cgccgggatt tccgcgattg gcattgtggc gctctccacc acctgcgcct acgctttcgc
     8281 ccgtatgcgc tttccaggca aagcgacgct gctgaaagga atgctgattt tccagatgtt
     8341 cccggcagta ctttcactgg tcgcgttgta tgcgttgttt gatcgtctgg gtgagtacat
     8401 tccattcatt ggcctgaata ctcacggcgg cgtaattttc gcgtatctgg gcgggattgc
     8461 gctgcatgtc tggaccatca aaggttattt cgaaaccatc gacagttcgc tggaagaagc
     8521 ggcggcgctg gatggtgcga caccgtggca ggccttccgc cttgtcctgt tgccgctgtc
     8581 agtaccgatt ctggcggttg tgttcatcct gtcgtttatc gctgccatta ctgaagttcc
     8641 ggtcgcgtcg ctattactgc gtgacgtaaa cagctacacc ctggctgtgg ggatgcagca
     8701 atacctcaac ccgcaaaact acctgtgggg tgactttgcc gccgctgccg tgatgtctgc
     8761 attaccgatc accatcgtct tcttgctggc tcaacgctgg ctggtcaacg gcctgacggc
     8821 aggtggtgtg aaaggttaaa gatgttgttc tgccaatgtt atgccgctgc accctcaact
     8881 tacgttatcc caacttgtga ctgttattcg gcgctccacg gagcgccttt ttttactccc
     8941 gcttcagccg tttcgaatta cacaaccaca gggtgatcac cagtaacagg atcgctgccg
     9001 agtagatcaa cacatccagt ggcgatttat gatcgacgat gatcaagcgc acaatggcgg
     9061 tgatcccaat atagacaaag taacgtagcg ggaagtgaaa accggactga aagtacttca
     9121 caatcagcgc gataaattcg aaatagagaa agtaaaccac cagcccttct accagctcat
     9181 atttactggt ttgttctggc gcgaacagca catcagccag atgcaccgtt tctttgccga
     9241 ggaagacaac caaaatcagg ccgaggcaca acaggccaag attgagtacg gtctgcaaaa
     9301 tggtggatat aaactccacg cgcggacgag agagtgacgt catagcagta cctccttcac
     9361 agtggcgagc ttcctgtata acgcaaaaat gtgacggaga tctatatttt ttgtgtatgt
     9421 tttgttcagc tcaattaagt gggcatctcc catcaatgtc tcatctggca aaacacacag
     9481 ccaaaaaaat cacccattca ggtgattccc agccaccagc aatgcgcgaa aaatcgacaa
     9541 tgttcctctg gaacaaatga aacgtaacct gataaaggtg gtaaaaatga agccttattt
     9601 tgctgctttg atgttatcag tctctgttct tcctgcttat gctggtccgc tcggtactgc
     9661 tgataaagcc gacctaccgc aaagcaatgt ctccagtcca atgatggccc agtcgctcag
     9721 gcaaccagac ctgcaaccga tatcgacgga caggaagaca gaatgttttc gcctttacac
     9781 accagatcgc aaaccggggg tgaactgcgt tcctgatggc tcgacaggcc attaagaatg
     9841 agggtgccag tgagtgcgaa aactggcacc ttttccatga cttagcggaa attgacgcta
     9901 cggtcgctgg tcatgtcata caactggaac ttacgcccaa gttgctgacc accgtcacgc
     9961 gtcagcggcg tccagccaat tgccgcacgg ctgcgtgtcg ggccagacga gaagagatcc
    10021 agcggtacag agacatacac gcctttggta aagtcccctt cgccgtactc ctctttcgaa
    10081 acgttggtga tcgtggcata gccacccacc accacgccgc tatcaaagcg tttggcgatc
    10141 tccagcgtgc cgcctttatc ccctgccaga tactgcccga cgctcgcttt cactaacaca
    10201 tcctgagcaa aagatggcgt ccagtatgcg gtcagatgtc cggttttcac gctgtagtcg
    10261 gtgaatttca tcatatcttt tgcactacgc cagtcgcgct gtttaacgta gttggcatcc
    10321 acaccaaacg cccagttgct gtccagcggg cgatacaaca cttctgcccc cgcaccgcca
    10381 aacatggttt cgagataacc tccgtagacc tgaccgtaga agccgttgcc cagatgctgg
    10441 aagtagttgg cttgcaggtt attcacatag acatcgttct gcacatactc gcgcacatgg
    10501 gtacgaacgc gcggtaagtg cgagtcctgc ggcggattgg tgtagttaaa cttgtcgtag
    10561 ttgttggcaa ggttagcaaa caggctgccg gtggtcagca gatggtccgt cagccacaaa
    10621 tccgccgttc ccatcacgcc cagctgatac atgtaaaagt tttccgggcc accgaccgac
    10681 tggttcagca ccggatcgat atggaaatca aagcgtgatt tgtcgatata ccagccctgc
    10741 tcggtggact gcggaaccac tggctcgacg cgtttttgcg ccagcttcgt ttcgtggccc
    10801 aacggctctc cggcgagatg atttttcagg ctggcgacat cggtttccgt cgtcacctgc
    10861 ggcatgttaa ggcgattttc cgtaatgcgg atcgttttga tcccatccgg cagatcgttc
    10921 atcacgatcc gattagcacg gatgatccct tcacgcgaat cacgatattt cacctgctcg
    10981 ccggtgacat acagcgtatc gcctttcgtc tggatctgcg gatcggccag tccggcgttg
    11041 tatttcaaca gcgttaactg attcgccacc accgagtgct gcaaaatggc atcctgcggc
    11101 tgcggttgat attgcgggcg ggcgttatcg ttgtacgaag gacgtagatc gttaaagttg
    11161 gtgcgcagcg tgacgccaaa cataaaggtg ttgccacgtt catagctaag gttaacgtcg
    11221 gcccaatcgg taacgcgata aatcgccccg acgttaaact tacttttttg ctccagcttc
    11281 ccggcaaaat cctgctgata attattgcct tcatactcca gtttcaggcg cagcggttgc
    11341 cagggcgtct ggtattccac gccgccaaac agtgaggcag gaccgtggaa catctggcta
    11401 ccgtcgatag atcccgcctg tttgtagctg ttatcgcgat agcaatattt atcactggct
    11461 gaacagagcg gatttttcac attaccgctg gtgcccagat atccccagcc caggccgagc
    11521 gtaaaatcga acggccccca ggctttgctg gcaacaagat attccgcatc aaacagcccc
    11581 gtaccgccga tatcccgcgc accaaccgcc acttgcggca gccaataact ctcttcccac
    11641 aaacgcagtt tgagatcgaa ggctttatct ttatacgttt gatcaccaga gaacgcttcg
    11701 acgctgctgt actgccgggt gcgcacgtcg gtgtagcgca gcgttgtttc cagccacggg
    11761 aagagttgca ctgaagctgc gtaataacgg tactgatcgt tatcgcgata gttgaggctc
    11821 aactcccctt cccgcgccat gcgtgcggtg ggcgtttgta ataatcctac gccaccgaaa
    11881 tccgactgcg acggaccaat gggcgcagga tatgtttcgc cgtagcaagc tgtgctaatg
    11941 cccagcgcca gtaagctaag cagatgtctt tttttcatta ttgaggtatc cgctgcgtca
    12001 gagtctgaag aatgtcggcg ttaagggcat cagacgtctc actccagacg gagtccgcga
    12061 ggccaacata aataatgctg ccgggcatcg gctctacgtg acgcttgttc cagtaagcca
    12121 ccggcgcttt ttgcgtgcgt ccgtccgggt aaaccaccca cgcgtagctg cgatccgcac
    12181 cgctgagcag gctctggtca gagagatagc tcgtcacgtc gcgacctgga gtgaatgact
    12241 gcttgccagg acgactgata agcccgaaca acgtgaccgt ggacggcggc ggtccgaccc
    12301 acagcgtgta gttgccctgc aacggcgggt taccgcgttc ggcaacgcgg acgatatcag
    12361 gatcaagatt gattttttgc ctgcccgtca ctttcaacgc ctgaatttgc tggcgtaagg
    12421 cgttaattgc ggcggcatcg tcggcgctgg agtctgcggt tagttctgcc agccgtgtca
    12481 gcaacgcctg ctgctgacgc aatgctgccg ccgtggccag ctcttcgcta atcaccgcac
    12541 caggccacca gctgtttgcc agctgcggtt ggcctaccag atcgattaaa tgctctgcac
    12601 ccgtcagcgt tttggcctca ctgctgccat tgctgaacac cttgacggtt cctgccgcga
    12661 agaccgatga cgcccccaca ctcaaaatca atgcgacaat agtttgttta atcattgttt
    12721 tgccgccttg atgagagtgg ttttcaccgg gaaataatcc gcgccgagat actgttccga
    12781 ctggcgaatt tgcccttcgc tgtcgatcca gtagcggtta tgccagcgcg cctggtcggt
    12841 ggagacttct tcgtccagca cgcgaaccgg ggtttcatcg ctgccgactt tgacggtatc
    12901 ggtgccatcc catttgaaga ctgagcgtgc ggtggcgtag cgtacctgct ggtactcggt
    12961 ccagcccatc gtgcgcgtcc atgttgcacc atcaacaatt tgtgcgggtt taatcagcgg
    13021 gtcggcagca aggttattca cttcaatcag gttgtcgccg ccaagcaaag tcttcaccag
    13081 acgaccatgt tgtgtgacga gagtggcctg atcctgagtg acccattttt gttgtccgtc
    13141 ttcagcaaag gccagcacca caaacaattg cggcccgcca ttaagctgca tgtactggct
    13201 ggcgtagggc atattttgaa tatcatcgtc cgtcagctgt acgcctggcg tgccgaacag
    13261 actgtcccac agcgaattgc ccagctcttt agtcgtggct gaacaggcct gtaatagcag
    13321 gcagataaga atgagtgcag gtcgcttcac gactcttctc cagaggggca gaataaccac
    13381 accggagtgt ggttatggta aatcccttca tacttcaagc cacagatgca atgactcgaa
    13441 ttattttggg gatacatact ttattactgg gtactggtgg tcgtggttgt tgtggtcccg
    13501 gtattagaac catcaccgcc accggttgcc gcgagcgcga cacccaccgc cgagcttacg
    13561 gtgctgacgc tggtcgcgga ggaactcccc gccgaaaccg acgttgctgc cgatcctgcc
    13621 gcttcgccca cctgtacagg tgcagcccac gcagaagtcg ccgcaagcgc agatatggca
    13681 aaaatgccat acagaacttt tttcataaca atttcccttc attgaatgaa tggagattta
    13741 cccaaaaaca tttcgggcgg gatcgagtat acacaactaa agcatgcgaa ttacggcgca
    13801 gggaattagc gatggggttt taggataatt ggaatgaata t
//
LOCUS       DADXDL010000113        13689 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.113, whole genome shotgun sequence.
ACCESSION   DADXDL010000113 DADXDL010000000
VERSION     DADXDL010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13689)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13689)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13689
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.113"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            143..1201
                     /gene="citC"
                     /locus_tag="IRB70_004151"
     CDS             143..1201
                     /gene="citC"
                     /locus_tag="IRB70_004151"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415151.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HBC0633996.1"
                     /translation="MFGNDIFTRVKRSENKKMAEIAQFLHENDLSVDTTVEVFITVTR
                     DEKLIACGGIAGNIIKCVAISESVRGEGLALTLATELINLAYERHSTHLFIYTKTEYE
                     ALFRQCGFSTLTSVPGVMVLMENSATRLKRYAESLKKFRHPGNKIGCIVMNANPFTNG
                     HRYLIQQAAAQCDWLHLFLVKEDSSRFPYEDRLDLVLKGTADIPRLTVHRGSEYIISR
                     ATFPCYFIKEQSVINHCYTEIDLKIFRQYLAPALGVTHRFVGTEPFCRVTAQYNQDMR
                     YWLETPTISAPPIELVEIERLRYQEMPISASRVRQLLAKNDLTAIAPLVPAVTLHYLQ
                     NLLEHSRQDAAARQKTPA"
     gene            1216..1512
                     /gene="citD"
                     /locus_tag="IRB70_004152"
     CDS             1216..1512
                     /gene="citD"
                     /locus_tag="IRB70_004152"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HBC0633997.1"
                     /translation="MKINQPAVAGTLESGDVMIRIAPLDTQDIDLQINSSVEKQFGDA
                     IRTTILDVLARYNVRGVQLNVDDKGALDCILRARLEALLARASGIPALPWEDCQ"
     gene            1509..2417
                     /gene="citE"
                     /locus_tag="IRB70_004153"
     CDS             1509..2417
                     /gene="citE"
                     /locus_tag="IRB70_004153"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415149.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HBC0633998.1"
                     /translation="MISASLQQRKTRTRRSMLFVPGANAAMVSNSFIYPADALMFDLE
                     DSVALREKDTARRMVYHALQHPLYRDIETIVRVNALDSEWGVNDLEAVVRGGADVVRL
                     PKTDTAQDVLDIEKEILRIEKACGREPGSTGLLAAIESPLGITRAVEIAHASERLIGI
                     ALGAEDYVRNLRTERSPEGTELLFARCSILQAARSAGIQAFDTVYSDANNEAGFLQEA
                     AHIKQLGFDGKSLINPRQIDLLHNLYAPTQKEVDHARRVVEAAEAAAREGLGVVSLNG
                     KMVDGPVIDRARLVLSRAELSGIREE"
     gene            2428..3960
                     /gene="citF"
                     /locus_tag="IRB70_004154"
     CDS             2428..3960
                     /gene="citF"
                     /locus_tag="IRB70_004154"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HBC0633999.1"
                     /translation="MTQKIEQSQRQERVAAWNRRAECDLAAFQNSPKQTYQAEKARDR
                     KLCANLEEAIRRSGLQDGMTVSFHHAFRGGDLTVNMVMDVIAKMGFKNLTLASSSLSD
                     CHAPLVEHIRQGVVTRIYTSGLRGPLAEEISRGLLAEPVQIHSHGGRVHLVQSGELNI
                     DVAFLGVPSCDEFGNANGYSGKACCGSLGYAMVDADNAKQVVMLTEELLPYPHNPASI
                     EQDQVDLIVKVDRVGDAAKIGAGATRMTTNPRELLIARSAADVIVNSGYFKEGFSMQT
                     GTGGASLAVTRFLEDKMRSRDIRADFALGGITATMVELHEKGLIRKLLDVQSFDSHAA
                     QSLARNPNHIEISANQYANWGSKGASVDRLDVVVLSALEIDTQFNVNVLTGSDGVLRG
                     ASGGHCDTAIASALSIIVAPLVRGRIPTLVDNVLTCITPGSSVDILVTDHGIAVNPAR
                     PELAERLQEAGIKVVSIEWLRERARLLTGEPQPIEFTDRVVAVVRYRDGSVIDVVHQV
                     KE"
     gene            3964..4515
                     /gene="citX"
                     /locus_tag="IRB70_004155"
     CDS             3964..4515
                     /gene="citX"
                     /locus_tag="IRB70_004155"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HBC0634000.1"
                     /translation="MHLLPELASHHAVSIPELLVSRDERQARQHAWLKRHPVPLVSFT
                     VVAPGPIKDSEVTRRIFNHGVTALRALAAKQGWQIQEQAALVSASGPEGMLSIAAPAR
                     DLKLATIELEHNHPLGRLWDIDVLTPEGDILSRRDYSLPPRRCLLCEQSAAVCARGKT
                     HQLTDLLNRMEALLNDVDACNVN"
     gene            4490..5368
                     /gene="citG"
                     /locus_tag="IRB70_004156"
     CDS             4490..5368
                     /gene="citG"
                     /locus_tag="IRB70_004156"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HBC0634001.1"
                     /translation="MSMPATSTKTTKLATSLIDEYALLGWRAMLTEVNLSPKPGLVDR
                     INCGAHKDMALEDFHRSALAIQGWLPRFIEFGACSAEMAPEAVLNGLRPIGMACEGDM
                     FRATAGVNTHKGSIFSLGLLCAAIGRLLQLNQPVTPTTVCSTAASFCRGLTDRELRTN
                     NSQLTAGQRLYQQLGLTGARGEAEAGYPLVINHALPHYLTLLDQGLDPELALLDTLLL
                     LMATNGDTNVASRGGEGGLRWLQREAQTLLNNGGIRTPADLDYLRQFDRECIERNLSP
                     GGSADLLILTWFLAQI"
     gene            5418..6881
                     /gene="citT"
                     /locus_tag="IRB70_004157"
     CDS             5418..6881
                     /gene="citT"
                     /locus_tag="IRB70_004157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate/succinate antiporter CitT"
                     /protein_id="HBC0634002.1"
                     /translation="MSLAKDNIWKLLAPLVVMGVMFLIPVPDGMPPQAWHYFAVFVAM
                     IVGMILEPIPATAISFIAVTICVIGSNYLLFDAKELADPAFNAQKQALKWGLAGFSST
                     TVWLVFGAFIFALGYEVSGLGRRIALFLVKFMGKRTLTLGYAIVIIDILLAPFTPSNT
                     ARTGGTVFPVIKNLPPLFKSFPNDPSARRIGGYLMWMMVISTSLSSSMFVTGAAPNVL
                     GLEFVSKIAGIQISWLQWFLCFLPVGVILLIIAPWLSYVLYKPEITHSEEVATWAGDE
                     LKTMGALTRREWTLIGLVLLSLGLWVFGSEVINATAVGLLAVSLMLALHVVPWKDITR
                     YNSAWNTLVNLATLVVMANGLTRSGFIDWFANTMSTHLEGFSPNATVIVLVLVFYFAH
                     YLFASLSAHTATMLPVILAVGKGIPGVPMEQLCILLVLSIGIMGCLTPYATGPGVIIY
                     GCGYVKSKDYWRLGAIFGVIYISMLLLVGWPILAMWN"
     gene            6995..7801
                     /gene="rna"
                     /locus_tag="IRB70_004158"
     CDS             6995..7801
                     /gene="rna"
                     /locus_tag="IRB70_004158"
                     /EC_number="4.6.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease I"
                     /protein_id="HBC0634003.1"
                     /translation="MKAFWRNAALLAVSLLPFSSANAVALQAKQYGDFDRYVLALSWQ
                     TGFCQSQHDRNRNERDECRLQTETTNKADFLTVHGLWPGLPKSVAARGVDERRWMRFG
                     CATRPIPNLPEARASRMCSSPETGLSLETAAKLSEVMPGAGGRSCLERYEYAKHGACF
                     GFDPDAYFGTMVRLNQEIKESEAGKFLADNYGKTVSRRDFDAAFAKSWGKENVKAVKL
                     TCQGNPAYLTEIQISIKADAINAPLSANSFLPQPHPGNCGKTFVIDKAGY"
     gene            8031..8441
                     /gene="rnk"
                     /locus_tag="IRB70_004159"
     CDS             8031..8441
                     /gene="rnk"
                     /locus_tag="IRB70_004159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside diphosphate kinase regulator"
                     /protein_id="HBC0634004.1"
                     /translation="MSRPTIIINDLDAERIDILLEQPAYAGLPIADALNAELDRAQMC
                     SPEEMPHDVVTMNSRVKFRNLSDGEVRVRTLVYPAKMTDSNTQLSVMAPVGAALLGLR
                     VGDSIHWELPGGVATHLEVLELEYQPEAAGDYLL"
     gene            8797..9225
                     /gene="uspG"
                     /locus_tag="IRB70_004160"
     CDS             8797..9225
                     /gene="uspG"
                     /locus_tag="IRB70_004160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein UspG"
                     /protein_id="HBC0634005.1"
                     /translation="MYKTIIMPVDVFEMELSDKAVRHAEFLAQDDGVIHLLHVLPGSA
                     SLSLHRFAADVRRFEEHLQHEAEERLQTMVSHFTIDPSRIKQHVRFGSVRDEVNELAK
                     ELDADVVVIGSRNPSISTHLLGSNASSVIRHANLPVLVVR"
     gene            complement(9346..10911)
                     /gene="ahpF"
                     /locus_tag="IRB70_004161"
     CDS             complement(9346..10911)
                     /gene="ahpF"
                     /locus_tag="IRB70_004161"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017455864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBC0634006.1"
                     /translation="MLDTNMKTQLKAYLEKLTKPVELIATLDDSAKSAEIKELLAEIA
                     ELSDKVTFKEDNSLPVRKPSFLITNPGSNQGPRFAGSPLGHEFTSLVLALLWTGGHPS
                     KEAQSLLEQIRHIDGDFEFETYYSLSCHNCPDVVQALNLMSVLNPRIKHTAIDGGTFQ
                     NEITDRNVMGVPAVFVNGKEFGQGRMTLTEIVAKIDTGAEKRAAEELNKRDAYDVLIV
                     GSGPAGAAAAIYSARKGIRTGLMGERFGGQILDTVDIENYISVPKTEGQKLAGALKVH
                     VNEYDVDVIDSQSASKLIPAAVEGGLHKIETASGAVLKARSIIVATGAKWRNMNVPGE
                     DQYRTKGVTYCPHCDGPLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLEFAPEMKA
                     DQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFVQIG
                     LLPNTNWLEGAVERNRMGEIIIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEGAKAS
                     LSAFDYLIRTKTA"
     gene            complement(11040..11603)
                     /gene="ahpC"
                     /locus_tag="IRB70_004162"
     CDS             complement(11040..11603)
                     /gene="ahpC"
                     /locus_tag="IRB70_004162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003858764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit C"
                     /protein_id="HBC0634007.1"
                     /translation="MSLINTKIKPFKNQAFKNGEFIEITEKDTEGRWSVFFFYPADFT
                     FVCPTELGDVADHYEELQKLGVDVYAVSTDTHFTHKAWHSSSETIAKIKYAMIGDPTG
                     ALTRNFDNMREDEGLADRATFVVDPQGIIQAIEVTAEGIGRDASDLLRKIKAAQYVAS
                     HPGEVCPAKWKEGEATLAPSLDLVGKI"
     gene            11975..12721
                     /gene="dsbG"
                     /locus_tag="IRB70_004163"
     CDS             11975..12721
                     /gene="dsbG"
                     /locus_tag="IRB70_004163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308670.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbG"
                     /protein_id="HBC0634008.1"
                     /translation="MLKKILLLALLPAIAFAEELPAPVKAIEKQGITIIKTFDAPGGM
                     KGYLGKYQDMGVTIYLTPDGKHAISGYMYNEKGENLSNTLIEKEIYAPAGREMWQRME
                     QSHWLLDGKKDAPVIVYVFADPFCPYCKQFWQQARPWVDSGKVQLRTLLVGVIKPESP
                     ATAAAILASKDPAKTWQEYEASGGKLKLNVPANVSTEQMKVLSDNEKLMDDLGANVTP
                     AIYYMSKENTLQQAVGLPDQKTLNIIMGNK"
     gene            12926..>13689
                     /locus_tag="IRB70_004164"
     CDS             12926..>13689
                     /locus_tag="IRB70_004164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0634009.1"
                     /translation="MANLYDLKKFDLNLLVIFECIYQHLSISKAAESLYITPSAVSQS
                     LQRLRAQFNDPLFIRSGKGIAPTTTGLNLHHHLEKNLRGIEQTINIVNKSELKKNFII
                     YGPQLISCTNNNMLIRCLRQDTSIDIECHDILLSAENAEELLVQRKTDLAITLQPVIS
                     RSVICMPLHTIRNSLICSNKHPRITDTSNYEQIIAEEFTLLISKSAGIDEIQMDIDER
                     FMNRKVSFRSSSLMTIINSISVTDLLGIVPTELYNL"
BASE COUNT         3321 a         3556 c         3398 g         3414 t
ORIGIN      
        1 ggatgtatag cgaaaggaga aaaagatata cctcgatcgc ccccctttct cccaagtgaa
       61 aataaaaggt tatcagtttg caacatcgaa caacattcgt tgcaaatcga taacaacatg
      121 caccttcagg atactattta ttatgttcgg caatgatatt ttcacccgtg taaaacgttc
      181 agaaaataaa aaaatggcgg aaatcgccca attcctgcat gaaaatgatt tgagcgttga
      241 caccacagtc gaagtattta ttaccgtaac ccgcgatgaa aagcttatcg cgtgcggtgg
      301 aattgccgga aatattatta aatgcgttgc tatcagtgaa tccgttcgcg gtgaaggact
      361 ggcgctgaca ttagccactg aattgataaa cctcgcctat gagcggcaca gcacgcatct
      421 gtttatttat accaaaaccg aatacgaggc gctgttccgc cagtgcggtt tttccacgct
      481 gaccagcgta cccggcgtga tggtgctgat ggaaaacagc gccacgcgac tgaaacgcta
      541 tgccgaatcg ctgaaaaaat ttcgtcatcc agggaacaag attggctgca ttgtgatgaa
      601 cgccaatccc tttacgaatg gtcaccgtta tctgattcaa caggctgcgg cacagtgcga
      661 ctggttgcat ctgtttttag tcaaagaaga ttcttcacgc ttcccctatg aagaccggct
      721 ggatctggtg ttaaaaggca ccgccgatat tccacgcctg actgtgcatc gcggctccga
      781 atacatcatc tcccgcgcta cgttcccttg ctacttcatt aaagaacaga gcgtcattaa
      841 ccattgttac accgaaattg atctgaagat tttccgtcag tacctcgctc ccgcgctggg
      901 tgtaactcac cgctttgtcg gtactgaacc cttttgtcgc gttaccgccc agtacaacca
      961 ggatatgcgc tactggctgg aaacgccgac tatctccgca ccgcccatcg aactggttga
     1021 aattgagcgg ctgcgttacc aggagatgcc gatatccgct tcccgggtac gtcaactgct
     1081 ggcgaaaaac gatctcacgg ctatcgcgcc gctggtccct gcagtcacgc tgcattattt
     1141 gcagaacctg cttgagcact cccgccagga cgcggcagct cgtcaaaaga cccccgcatg
     1201 agaaacaggt gaaaaatgaa aataaaccag cccgccgttg caggcaccct tgagtctggg
     1261 gatgtgatga tacgcatcgc cccactcgat acgcaggata tcgacctgca aatcaacagc
     1321 agcgttgaga aacagtttgg cgatgcaatt cgcaccacca ttctggacgt tctcgcccgc
     1381 tacaacgtgc gcggcgtaca gctgaatgtc gatgacaaag gcgcactgga ctgcatttta
     1441 cgtgcacgac tggaagccct gctggcacgc gccagcggta tcccggctct gccatgggag
     1501 gattgccaat gatttccgct tcgctgcaac aacgtaaaac tcgcacccgc cgcagcatgc
     1561 tgtttgtgcc aggtgccaat gccgcgatgg tcagcaactc attcatctac ccggctgatg
     1621 ccctgatgtt tgacctcgaa gactccgtgg cattgcgtga aaaagacaca gcccgccgca
     1681 tggtttacca cgcgctgcaa catccgctgt atcgcgatat tgaaaccatt gtgcgtgtaa
     1741 acgcgctgga ttccgaatgg ggtgttaacg acctggaagc cgtcgttcgc ggtggtgcgg
     1801 acgttgtgcg tctgccgaaa accgataccg ctcaggatgt tctggatatc gaaaaagaga
     1861 tcctgcgcat cgaaaaagcc tgtggtcgtg aacccggcag caccggcctg ctggcagcga
     1921 ttgaatctcc gctgggcatt acccgcgcag tggaaatcgc tcacgcttcc gagcgtttga
     1981 tcggtatcgc cctcggtgca gaagactatg tgcgcaacct gcgtacagaa cgctctccgg
     2041 aaggaactga actgctgttc gcacgctgct ccattttgca ggccgcgcgc tctgcgggta
     2101 ttcaggcgtt cgataccgtc tattccgacg ctaacaacga agccggattc ctgcaagaag
     2161 ccgcccacat caaacagctg ggctttgacg gcaaatcgct gatcaacccg cgtcagattg
     2221 atctgctgca caacctctac gcaccgactc agaaagaagt ggatcacgcc cgccgcgtcg
     2281 tagaagccgc tgaagccgcc gctcgcgaag gcctcggcgt ggtttccctg aacggcaaga
     2341 tggtagacgg tccggttatc gatcgcgccc gtctggtgct ctcccgcgca gaactttccg
     2401 gcatccgcga agaataaggc aatcaaaatg acgcagaaaa ttgaacaatc tcaacgacaa
     2461 gaacgggtag cggcctggaa tcgtcgcgct gaatgcgatc ttgccgcttt ccagaactcg
     2521 ccaaagcaaa cctaccaggc tgaaaaagcg cgcgatcgca aactgtgcgc caacctggaa
     2581 gaagcgattc gtcgctctgg cttacaggac ggtatgacgg tttccttcca tcacgctttc
     2641 cgtggcggtg acctgaccgt caatatggtg atggacgtca tcgcgaagat gggctttaaa
     2701 aacctgactc tggcctccag ctccctgagt gattgccatg cgccgctggt agaacacatt
     2761 cgccagggcg tggttacccg catttatacc tctggcctgc gcggtccact ggcggaagaa
     2821 atctcccgtg gtctgctggc ggaaccggtg caaatccact ctcacggcgg acgtgtgcat
     2881 ctggtacaga gcggcgaact gaatatcgac gtggctttcc tcggcgtccc gtcctgtgat
     2941 gaattcggta atgccaacgg ctactccggt aaagcctgct gcggctccct cggctatgca
     3001 atggttgatg ccgacaacgc aaaacaggtc gtgatgctta ccgaagaact gctgccttat
     3061 ccgcataatc cggcaagcat tgagcaagat caggttgatc tgatcgtcaa agttgatcgc
     3121 gttggcgatg ctgcaaaaat cggcgctggt gctacccgta tgaccactaa cccgcgcgaa
     3181 ctgcttattg cccgtagcgc tgcggatgtg attgttaact ctggctactt caaagaaggt
     3241 ttctccatgc agaccggcac cggcggcgct tcgctggcgg taacccgttt cctggaagac
     3301 aaaatgcgta gccgcgatat tcgcgccgac ttcgccctcg gcggtattac cgcaacgatg
     3361 gttgagctgc acgaaaaagg tttgatccgc aaactgctgg atgtgcagag ctttgacagc
     3421 catgctgcgc aatcgctggc ccgtaacccc aatcacatcg aaatcagcgc caaccagtac
     3481 gctaactggg ggtcgaaagg cgcatcggtt gatcgtctcg acgtggtggt actgagtgcg
     3541 ctggaaattg acacccagtt caacgttaac gtgctgaccg gctctgacgg cgtactgcgt
     3601 ggtgcttccg gtggtcactg cgataccgcg attgcctctg cgctttccat catcgtcgcg
     3661 ccgctggtac gcggtcgtat tccgacgctg gtggataacg tgctgacctg catcaccccg
     3721 ggctccagtg tcgatattct ggtcacagac cacggcatcg ctgttaaccc ggcacgtccg
     3781 gagctggcag aacgtctgca ggaagcgggg atcaaagtgg tttctattga gtggctgcgt
     3841 gaacgtgcgc gtctgctgac cggtgaacca cagccgattg aattcaccga ccgcgtcgtt
     3901 gccgttgtgc gttaccgcga tggctcggtg atcgatgttg tgcatcaggt gaaggaataa
     3961 gccatgcacc tgcttcctga actcgccagc caccatgcgg tgtcaattcc cgagctgctc
     4021 gtcagccggg atgaaaggca agcacggcaa cacgcctggc tcaagcgcca tcctgttcca
     4081 ctggtctcct ttaccgtggt tgcgcctggg ccaattaaag acagcgaggt cacacgccga
     4141 atttttaatc atggcgtgac agccttgcgt gccttagccg caaaacaggg ctggcaaatt
     4201 caggagcagg ctgcactggt ttccgccagc gggccggagg gcatgttgag cattgccgcc
     4261 ccggctcgcg acctcaagct cgccaccatt gagcttgaac ataatcatcc tctcgggcgg
     4321 ttatgggata tcgatgtcct gacacccgaa ggcgacattc tctcccgccg cgattattca
     4381 ctgccgcctc gccgctgcct gttgtgcgag caaagcgcag ctgtttgcgc gcgtggaaaa
     4441 acccatcaac tgaccgattt actcaaccgc atggaggcgc tgctgaacga tgtcgatgcc
     4501 tgcaacgtca actaaaacca caaagctcgc gacgtcatta atcgatgagt acgccctgtt
     4561 gggctggcgc gccatgctga ctgaagtcaa tctgtcaccg aaaccaggcc tcgtggatcg
     4621 cattaactgc ggtgcgcaca aagatatggc gctggaagat ttccaccgca gcgcgctggc
     4681 gattcagggc tggttacccc gtttcattga atttggtgcc tgtagtgcag aaatggcacc
     4741 ggaagcagta ctcaacggat tacgcccaat tggtatggct tgcgaaggtg atatgttccg
     4801 cgccactgcg ggtgtaaaca cgcataaagg aagcattttt tctttagggc tactgtgtgc
     4861 ggcaattggc cgtttgcttc agctcaacca gccggtaacg ccaacaaccg tttgttcgac
     4921 ggcggcaagt ttctgtcgtg gcctgaccga tcgcgaactg cgtaccaata attcacaact
     4981 gacggcaggt caacggttgt accagcagct tggccttacc ggcgcacgcg gtgaagccga
     5041 agcgggttat ccactggtga tcaatcacgc cctgccgcat tacctcactc tgctggatca
     5101 ggggttagat cctgaactgg cattgctcga taccttgctc ctactgatgg ctactaacgg
     5161 cgataccaac gttgcatcgc gcggtggcga ggggggcctg cgctggctac agcgcgaggc
     5221 gcaaacacta ttaaacaatg ggggcatccg aacccccgcc gatctcgatt atctccggca
     5281 gttcgacagg gagtgtatcg aacgaaatct cagtccaggc ggcagtgccg acctgctgat
     5341 tcttacctgg tttttagcac agatttaata atttaagcac ttgataaaat tggaatatta
     5401 attgtcggag aacccgtatg tctttagcaa aagataatat atggaaatta ttggcgcccc
     5461 tggtggtgat gggtgtcatg tttcttatcc ctgtacctga cggtatgccg ccgcaggcgt
     5521 ggcattactt tgcagtgttt gtggcaatga ttgtcggcat gatcctcgag ccaattccgg
     5581 caacggcgat cagttttatt gcggttacta tttgcgttat tggcagtaat tacctgctct
     5641 ttgatgccaa agaattagct gacccagcgt ttaatgcgca aaaacaggcg ctgaaatggg
     5701 gtctggctgg tttttccagc accacggtat ggctggtatt tggcgcattt atttttgcat
     5761 tagggtatga agtttccggg ttaggtcgtc gcattgccct tttcctggtg aaattcatgg
     5821 gcaaacgcac gctgacgttg ggttatgcga ttgtcattat cgacattctg ctggcaccgt
     5881 ttacaccgtc caacaccgcg cgtaccgggg gtacggtttt tccggtcatt aaaaacctgc
     5941 cgccgctgtt taaatcattc ccgaacgatc cgtccgcgcg tcgtattggc ggctatttga
     6001 tgtggatgat ggtcattagt accagtctga gttcgtccat gtttgtcacc ggtgcggcac
     6061 caaacgtgct gggtctggag ttcgtcagca aaattgctgg tatccagatt agctggttgc
     6121 agtggttcct ctgcttcctg ccggttgggg ttatcttgct tatcattgcg ccgtggcttt
     6181 cctacgtgct gtacaaaccg gaaatcacac acagtgaaga agtggcaacc tgggcgggtg
     6241 atgaactaaa aaccatgggt gcgctgacgc gcagagagtg gacgctgatt ggccttgtat
     6301 tgctcagctt aggtttgtgg gtatttggca gtgaagtcat taatgctact gcggtaggtc
     6361 tgctggcagt ttcgctgatg ctggcgctgc acgttgtgcc gtggaaagac attactcgct
     6421 ataacagcgc atggaacacg ctggtcaacc tggcaacgct ggttgttatg gcgaatggcc
     6481 tgacccgttc tggctttatc gactggttcg ccaacacgat gagtacacac ctggaaggct
     6541 tctcaccaaa cgcaacggtg attgtactgg ttctggtgtt ctactttgca cactacctgt
     6601 ttgccagcct gtctgcgcac accgcaacca tgctgccggt tattctggcc gtcggtaaag
     6661 gtattccggg cgtaccaatg gaacaactgt gtattctgct ggtgctgtct atcggtatca
     6721 tgggctgtct gacgccgtat gcaaccggtc ctggggtgat tatttacggc tgtggctatg
     6781 tgaaatcaaa agattactgg cgacttggtg caatcttcgg ggtgatttac atctctatgc
     6841 tgctgttggt tggctggccg attctcgcca tgtggaacta atacgttcgc caaacgctga
     6901 ataaatcatc acgcccgcca ggtaagccca cctggcgggc ttttttatga tttaatagat
     6961 agtattcagt atatgtatga gttccacacc cattatgaaa gcattctggc gtaacgccgc
     7021 gttgctcgcg gtttctctgc ttcccttctc ttctgccaac gccgtggcgt tgcaggcaaa
     7081 acagtatggc gattttgatc gctatgtcct ggccctctcc tggcaaaccg gattttgcca
     7141 gagtcaacac gatcgaaatc gtaacgaacg agatgaatgt cgcctgcaaa ccgaaacgac
     7201 caacaaagct gattttctga ccgtacatgg tctgtggcca ggattgccta aatcggttgc
     7261 tgcccgtggt gttgatgaac gccgctggat gcgcttcggt tgcgctactc gcccaatccc
     7321 gaatctacca gaagcgcgcg ccagccgaat gtgttcatct ccggaaaccg ggttatcgct
     7381 ggaaacggcc gctaaactaa gtgaagtcat gccaggagct ggcggacgtt cctgcctgga
     7441 acgctacgaa tatgccaaac acggtgcctg ctttggtttt gatccagacg catacttcgg
     7501 cacgatggta cgcctgaatc aagaaattaa agagagcgaa gccggaaaat tccttgcgga
     7561 taactacggt aaaacagtga gccgccgtga ctttgatgcc gcctttgcca aaagctgggg
     7621 aaaagagaac gtgaaagcag ttaagctaac gtgccagggt aaccctgcgt atttgactga
     7681 aattcagatc tcgatcaaag ctgacgccat caacgctccg ctttctgcca actcattctt
     7741 gccacaacca cacccaggca actgtggcaa aacctttgtg attgataaag ctggttatta
     7801 atcctctgat ttacaaaaca cgctaattcg tcttccataa accatgacga ttaagattta
     7861 tacataatgc gctacattga ggaattccct gaatgtgacg caaatcactt caaagagtga
     7921 gcaacagtca gtatcatcat gtgagttaaa ccctcgccgc ctgacggtga gggttttctt
     7981 ttgggtatgt ttatctgcga cactcgcagt accgacgaca tggagtaaaa atgtccagac
     8041 caactatcat cattaacgac ctggatgccg aacgcatcga tattctgctg gagcaacccg
     8101 cctatgctgg tttgccaatc gccgacgcgt taaacgcaga gttggatcgc gcccaaatgt
     8161 gttcgccaga agagatgcca cacgacgtgg tgacaatgaa cagccgggtt aaattccgca
     8221 atcttagcga tggcgaagtg cgtgtgcgca cgctggtgta tccggcaaaa atgaccgaca
     8281 gcaatactca gctttccgtt atggctccgg taggtgccgc actgctgggg ctgcgcgttg
     8341 gcgattccat tcactgggaa cttccgggcg gcgttgcaac ccaccttgaa gtgctggaac
     8401 tcgaatacca gccagaagct gctggcgact acctgcttta atcccatctg cacaagcgac
     8461 aactcgcttt gcccagagga tgcactcgca tcctctttcc gctcaaatat caaccagatt
     8521 tatcattttg ctcttaagcg cagcattcta atctgaactg gttattcatc tgcggaacct
     8581 catatgagcg aagctctcgg tatcactgca ttttatatat tcatagcagc aattattgtt
     8641 gctgcagtgc tataccttga acaacgctgg tagcgcctgg ttttatttat tttccagctc
     8701 aatagccaat tcagatcaaa tcagcctcgc aaatcataga ttcataacca ataatgtgct
     8761 gttatgtata catgcaaaaa caaggagaga atgcttatgt acaaaacaat catcatgcca
     8821 gtggatgttt tcgaaatgga attgagcgac aaagcggttc gccacgctga attcctcgcc
     8881 caggatgacg gagttattca tctacttcac gtactaccgg ggtccgccag cctgagtctg
     8941 caccgttttg ccgctgatgt acgtcgtttt gaagagcatc tgcaacatga agcagaagaa
     9001 cgtctgcaaa cgatggtcag ccacttcacc atcgatcctt cccgcattaa gcaacatgtc
     9061 cgttttggta gtgtgcggga tgaagttaac gagttagcga aagaacttga tgcagatgta
     9121 gtagtgattg gttcgcgtaa cccatcaatt tcaactcatc tgttgggttc taacgcctcg
     9181 agcgtgatcc gccacgccaa tctgccggtg ctggttgtgc gttaattgcc agaataaata
     9241 tcccgccctg cccggagcca tccctgcagg gctttttaat gcaataaaaa agccgccagg
     9301 tttgaccccg gcggctaagc aattgcaggt gaatcttact tcttcttatg cagttttggt
     9361 gcgaatcagg tagtcaaaag cactcagaga ggctttggca ccttcgccag tagcgatgat
     9421 gatctgcttg tacggaaccg tcgtacagtc acccgctgcg aacacgcctt tgacgttggt
     9481 ttcgcatttc gcatcaatga taatctcgcc catgcggtta cgttcgactg cgccttcgag
     9541 ccagttggtg ttcggcagca gaccaatctg gacgaaaata ccggccagtt cgatgttgtg
     9601 aatatcgccg ctgacacgat cgcgatattc cagacctacg actttgctac cgtcgccttt
     9661 cacttccgtg gtttgcgcat tcagaataat gtcgacgttt ttcaggctgc gcagtttgtc
     9721 ctgcagaacc tggtcggctt tcatttctgg cgcaaattcc agcagcgtta cgtgctcaac
     9781 gatacccgcc aggtcaattg ccgcttccac gccggagtta ccgccgccga taaccgctac
     9841 gcgtttgcct ttaaacagcg ggccgtcgca gtgcgggcag taggtcacgc ctttggtgcg
     9901 atactgatct tcgcccggaa cgttcatgtt gcgccatttt gcaccggtcg ccacgataat
     9961 gctgcgtgct ttcagtaccg cgccagaagc tgtttcaatc ttatgcaggc cgccttcaac
    10021 cgctgccggg atcagtttgc tcgcgctctg actgtcgatc acatcaacgt cgtattcatt
    10081 aacatgaact ttcagcgcac ctgccagttt ctggccttcg gtcttcggta cagaaatgta
    10141 gttttcgata tcaacggtat cgaggatctg accaccaaaa cgttcgccca tcagaccggt
    10201 acggatgcct ttacgtgcgg agtaaattgc tgccgctgca cccgccgggc cggaaccaac
    10261 gattaatacg tcataagcat cacgcttgtt cagctcttct gccgcacgtt tttccgcacc
    10321 agtatcaatt ttggcaacga tttcagtcaa cgtcatgcgg ccctgaccaa actctttccc
    10381 gtttacgaac actgccggaa cgcccatcac gttgcgatcg gtgatttcgt tctggaaggt
    10441 gccgccgtca attgcagtgt gcttgatgcg cgggttcagt acgctcatca ggttcagcgc
    10501 ctgcaccacg tccgggcagt tgtggcaaga gagcgagtaa taggtttcga attcaaaatc
    10561 accgtcaata tggcgaatct gctccagcag agactgcgct tctttcgacg gatgaccacc
    10621 ggtccacagc aacgccagta ccagcgaggt gaactcgtgg cccagcgggg atcctgcaaa
    10681 acgtggcccc tggttggaac ctgggttagt gatcaggaaa gacggcttac gcaccggcaa
    10741 gctgttatct tctttaaagg tgactttgtc tgacagttct gcgatttcag ccaacagttc
    10801 cttgatttct gccgatttag cgctgtcatc cagcgtggca attaactcaa caggcttggt
    10861 caatttctca aggtaagcct tgagttgagt tttcatattt gtgtcgagca tgtttatctc
    10921 ctgggcttta aacatcatca tgcaagcggc ctctgcggct acctggatgc agcttgcatc
    10981 atggtgcggg gaagaaaatc gggtgccgca gcacccgatt aattacgcga ttgcggaact
    11041 tagattttac caaccaggtc cagagacgga gccagagttg cttcaccttc tttccattta
    11101 gccgggcaaa cttcacctgg gtgagaagct acgtactgtg ctgctttgat tttacgcagc
    11161 aggtcagacg cgtcacggcc aatgccttca gcggtaactt cgattgcctg gatgataccc
    11221 tgcgggtcaa caacgaaggt cgcacggtca gccagacctt catcttcacg catgttgtcg
    11281 aagttacggg tcagggcgcc agtcgggtcg ccgatcatcg catatttgat tttagcgatg
    11341 gtttcagagc tgctgtgcca tgctttgtgg gtgaagtgag tatcggtaga tactgcgtat
    11401 acgtctacgc ccagtttctg cagttcttcg taatggtcag caacgtcacc cagttcggtc
    11461 gggcatacga aagtaaagtc agccgggtag aagaagaaga cgctccagcg gccttcggta
    11521 tctttttcgg tgatttcgat gaattcgccg tttttgaatg cctggttttt aaaaggttta
    11581 attttggtgt taatcaagga catctatact tcctccgtgt tttcgatgag atgtaaggta
    11641 accaattttt gccgattcgg ctaatgcgtt tccattatca aatcgataag ttttacctta
    11701 caaccttcgt aagacaactt tgtgaacttt gcaccgccag cggcgataaa aagtaaaatg
    11761 gccccctttc caggtgaccg tgtaatctga actacccttt ggtatcttca gcgcctgcct
    11821 gcaggctgag gtgttgccct tacaaatgca acaacgacat ggattacaac accctcataa
    11881 acaaagggca atcacctgat ctaagctctt acctatgaca gtgataggtt atgcctttta
    11941 ctcgactttt gcactgactg aaaaggacaa attaatgtta aaaaagatac ttttactggc
    12001 tctgcttcct gcaatcgcct tcgcagagga acttcctgcc ccagtaaaag cgattgaaaa
    12061 acagggcatt acaatcatca aaacgttcga tgctcccgga ggaatgaaag gttatctcgg
    12121 caagtatcag gatatgggcg tcaccatcta cctgactcca gatggtaagc acgctatctc
    12181 cggttacatg tacaacgaga aaggtgaaaa cctgagtaac acacttatcg aaaaagaaat
    12241 ttacgcaccc gccggacgcg aaatgtggca acggatggaa caatcccact ggctcctcga
    12301 cggtaaaaaa gacgcgccgg tcattgtcta cgtcttcgcc gatccgttct gcccatattg
    12361 taaacagttc tggcagcagg ctcgcccgtg ggtagattct ggcaaagtgc aattaagaac
    12421 attgttggtt ggcgttatca agccagaaag cccggcgaca gcagcggcaa ttcttgcctc
    12481 caaagatccc gcaaaaacct ggcaagaata tgaagcctct ggtggcaagc ttaaactaaa
    12541 cgtgcctgca aacgtaagta cagagcaaat gaaagtgtta agcgataacg agaaactgat
    12601 ggacgatctg ggggcaaatg tcacgccagc tatctattac atgagtaagg aaaatacact
    12661 gcaacaggcc gtggggttgc ccgatcagaa aacgcttaat atcattatgg ggaataaata
    12721 aaagataatt catggatggt tgaaatatat tcctgctttt caaccatcct aaaaaagcat
    12781 gaattgctcg taacccacct gacagctatg ctattttaga aaatcttaat ccaaagttaa
    12841 gcagaaaaac ataacacata taaatacaac aacaatattg atcaagtgaa tgatttatgg
    12901 aagagacaat acaacggagt atgttatggc gaatctttat gatctaaaaa aatttgacct
    12961 caatttactg gtcatatttg aatgtattta tcaacatctc agcattagta aagcggcaga
    13021 atcattatat ataacgccct ctgctgttag tcagtcgtta caacgtttac gtgcgcaatt
    13081 taatgacccg ttattcattc gttcagggaa aggtatcgcg ccgactacga cagggttaaa
    13141 tctgcatcat catcttgaga aaaatctcag aggcattgaa caaacgatca atattgttaa
    13201 taagtctgag ctaaagaaaa attttattat ctacggtcct cagcttattt cttgtactaa
    13261 taacaacatg ctaatccgct gtcttagaca agatacttca atcgatatag aatgccatga
    13321 catactgctt tcagctgaaa atgccgaaga actgttggtt caacgcaaaa ctgacctggc
    13381 aattacacta caaccagtaa ttagccgctc tgtcatctgc atgccgttac atactattcg
    13441 caattctctt atatgtagca acaaacatcc tcgtattacc gataccagta actatgaaca
    13501 aattatcgcc gaagaattca ccctgttgat atctaaatca gcagggattg acgaaattca
    13561 aatggacata gatgaacgtt ttatgaaccg taaagtttca tttcgcagtt cttctttgat
    13621 gactataatt aatagtattt ctgttactga cttattaggc attgtgccca ccgaactgta
    13681 caatttaca
//
LOCUS       DADXDL010000114        13516 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.114, whole genome shotgun sequence.
ACCESSION   DADXDL010000114 DADXDL010000000
VERSION     DADXDL010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13516)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13516)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13516
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.114"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            126..497
                     /locus_tag="IRB70_004165"
     CDS             126..497
                     /locus_tag="IRB70_004165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000819704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choline transporter"
                     /protein_id="HBC0634010.1"
                     /translation="MKRFMDDVIQPAMTLVQEELNKQGTISHISDAVDDRIRLEVDLG
                     NELNFIYEVRLRGYISPTFALAAMDNDEQQTEQHRYYRAEVYLKEGGQNYDVMGWNQE
                     QLINDILDQYEKHLHFLHLVR"
     gene            560..1837
                     /locus_tag="IRB70_004166"
     CDS             560..1837
                     /locus_tag="IRB70_004166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2254 domain-containing protein"
                     /protein_id="HBC0634011.1"
                     /translation="MISRWKWMLKQTIKKLWFRATLFAIVAIITALLSILFKSMIPES
                     VSVKVGAEAVDNILNILASSMLAVTTFSLSIMVTAYGSATTNVTPRATRLVVEDVTTQ
                     NVLATFIGSFLFSLVGIIALNMGAYGERGRVILFIVTLVVIALILITLLRWIQHLTSL
                     GRVGETTAQVEQAAIETFIARARNPCLGGYPWLENNEQPKGTVAVYPKKIGYVEYIDM
                     VKLSKLLTNDPRHVYLVAQPGSFIHPSMPVLYLSQGQESSISTDLLETIIVSDARSFA
                     QDPRFCLSVMAEIACRALSPAVNDPGTAIDVIGRGVRILSTYAQNKSDEIEVKYPSVH
                     VAPLQNNDLLEDFFSPVARDGASMREIQIRVLKGLSMLSKGWPGIFAEAAHTLAFETL
                     EHATRADHIDSDRYLIKSTYYNLFSGEYSNKKT"
     gene            2085..2741
                     /locus_tag="IRB70_004167"
     CDS             2085..2741
                     /locus_tag="IRB70_004167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000145474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBC0634012.1"
                     /translation="MTGENRGRGRPRKTESTYADTRNDLIRSGLELLTQNGFLATGVD
                     AIVKNANVPKGSFYYYFKSKEDYAQTVLNAYDSFFEHKLKKHLHESSCTPMVRLENFI
                     NDACEGIKKYNFTRGCLVGNMMQESPGLPQSFIKVLQNILESWQALVAACLSDALSSG
                     EISSNMNNTQLAAIFWSGWEGAVMRSKLYCSTEPVYDFWSYFKTSVRYQSSQEATTGQ
                     "
     gene            complement(2922..3029)
                     /locus_tag="IRB70_004168"
     CDS             complement(2922..3029)
                     /locus_tag="IRB70_004168"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBC0634013.1"
                     /translation="MGNMAPFILRGVTLKGIDSVMFAKEKRAAIWQQAV"
     gene            4021..4247
                     /locus_tag="IRB70_004169"
                     /pseudo
     CDS             4021..4247
                     /locus_tag="IRB70_004169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229544.1"
                     /note="with IlvB catalyzes the formation of 2-acetolactate
                     from pyruvate, the small subunit is required for full
                     activity and valine sensitivity; E.coli produces 3
                     isoenzymes of acetolactate synthase which differ in
                     specificity to substrates, valine sensitivity and affinity
                     for cofactors; also known as acetolactate synthase small
                     subunit; frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase small subunit"
     gene            complement(4249..5031)
                     /locus_tag="IRB70_004170"
     CDS             complement(4249..5031)
                     /locus_tag="IRB70_004170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBC0634014.1"
                     /translation="METKQKERIRRLMELLKKTDRIHLKDAARMLEVSVMTIRRDLHQ
                     EDEPLPLTLLGGYIVMVNKPAPSMPVIHDVPKNHRDDLPIAILAAGMVNENDLIFFDN
                     GQEIPLVISMIPDAITFTGICYSHRVFVALNEKPNVTAILCGGTYRARSDAFYDASNS
                     SPLDSLNPRKIFISASGVHNHFGVSWFNPEDLATKRKAMNRGLRKILLARHALFDEVA
                     SASLAPISAFDVLISDRPLPADYVTHCQNGSVKIITPDSEDE"
     gene            5337..6257
                     /gene="rbsK"
                     /locus_tag="IRB70_004171"
     CDS             5337..6257
                     /gene="rbsK"
                     /locus_tag="IRB70_004171"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBC0634015.1"
                     /translation="MDIAVIGSNMVDLITYTNQMPKEGETLEAPAFKIGCGGKGANQA
                     VAAAKLNSKVLMLTKVGDDIFADNTIRNLESWGINTTYVEKVPCTSSGVAPIFVNANS
                     SNSILIIKGANKFLSPEDIDRAAEDLKKCKLIVLQLEVQLETVYHAIEFGKKNGIEVL
                     LNPAPALRELDMSYACKCDFFIPNETELEILTGMSVDTYDHIRLAARSLVDKGLNNII
                     VTMSEKGALWMTRDQEVHVPAFKVNAVDTSGAGDAFIGCFSHYYVQSGDVEAALKKAA
                     LFAAFSVTGKGTQSSYPSIEQFNEFLTLNE"
     gene            6285..7601
                     /gene="fucP"
                     /locus_tag="IRB70_004172"
     CDS             6285..7601
                     /gene="fucP"
                     /locus_tag="IRB70_004172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_462691.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-fucose:H+ symporter permease"
                     /protein_id="HBC0634016.1"
                     /translation="MNDKNIIQMPDGYLNKTPLFQFILLSCLFPLWGCAAALNDILIT
                     QFKSVFSLSNFASALVQSAFYGGYFLIAIPASLVIKKTSYKVAILIGLTLYIGGCTLF
                     FPASHMATYTMFLAAIFAIAIGLSFLETAANTYSSMIGPKAYATLRLNISQTFYPIGA
                     ASGILLGKYLVFSEGESLEKQMSGMNAEQIHNFKVLMLENTLEPYKYMIMILVVVMVL
                     FLLTRFPTCKVAQTSHHKRPSAMDTLRYLAKNSRFRRGIVAQFLYVGMQVAVWSFTIR
                     LALELGDINERDASNFMVYSFACFFIGKFIANILMTRFNPEKVLILYSVIGALFLAYV
                     ALAPSFSAVYVAVLVSVLFGPCWATIYAGTLDTVDNEHTEMAGAVIVMAIVGAAVVPA
                     IQGYIADMFHSLQLSFLVSMLCFVYVGVYFWRESKVRNALAEVTES"
     gene            7613..8626
                     /locus_tag="IRB70_004173"
     CDS             7613..8626
                     /locus_tag="IRB70_004173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020245959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBC0634017.1"
                     /translation="MSTRIYLWRALFGEKPRILLENSDFTVTSFRYDSGVEGLKIANS
                     RGHLIILPWMGQMIWDAQFDGHSLTMCNMFRQPKPATEVIETYGCFAFHSGLLANGCP
                     SAEDTHLLHGEMACAAMDEAWMELEGDMLRLTGRCEYVMGFGHHYLAQPTVVLHKSST
                     LFDIKMAVTNLASVDMPLQYMCHMNYAYIPNATFSQNIPDEILRLRESVPSHVNPTAQ
                     WLAFNQRIMQGEASLSTLNQPEFYDPEIVFFADKLDAYTDQPEFRMIAPDGTTFVTRF
                     SSAELNYVTRWILYNGEQQVAAFALPATCRPEGYLAAQRNGTLIQVAPQQTRTFTVTT
                     GIE"
     gene            9111..9302
                     /locus_tag="IRB70_004174"
     CDS             9111..9302
                     /locus_tag="IRB70_004174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001362728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634018.1"
                     /translation="MVTLALQPRGSVARIAREHDINDNLLFKWLRLSLIKGRISRRLP
                     LTNSSGIGVELLPVEMTLG"
     gene            complement(9549..10805)
                     /locus_tag="IRB70_004175"
     CDS             complement(9549..10805)
                     /locus_tag="IRB70_004175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011815933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBC0634019.1"
                     /translation="MDFFRFLMSDVLSEPAVLVGLIALIGLIAQKKPVTECIKGTVKT
                     IMGFVILGAGAGLVVSSLGDFANIFQHAFGIQGVVPNNEAIVSVAQKSFGKEMAMIMF
                     FAMVINIMIARFTPWKFIFLTGHHTLFMSMMVAVILATAGMTGITLIAVGSLVVGVAM
                     VFFPAIAHPYMKKVTGSDDVAIGHFSTLSYVLAGFIGSKFGNKEHSTEDMNVPKSLLF
                     LRDTPVAISFTMSIIFLVTCLFAGADAVKELSGGKNWFMFSIMQSITFAAGVYIILQG
                     VRMVIAEIVPAFKGISDKLVPNARPALDCPVVFPYAPNAVLVGFLSSFAAGLIGMFTL
                     YLLNMIVIIPGVVPHFFVGAAAGVFGNATGGRRGAILGAFAQGLLITFLPVFLLPVLG
                     DIGFANTTFSDADFGALGILLGIIVR"
     gene            complement(10818..11105)
                     /locus_tag="IRB70_004176"
     CDS             complement(10818..11105)
                     /locus_tag="IRB70_004176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004717867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBC0634020.1"
                     /translation="MKITVVCGNGLGTSLMMEMSIKSILKDLSVSADVDHVDLGSAKG
                     TSSDIYVGTKDIAEQLVAQSVAGKIVALENMIDKKAMRERLSVVLNELGAL"
     gene            complement(11121..11564)
                     /locus_tag="IRB70_004177"
     CDS             complement(11121..11564)
                     /locus_tag="IRB70_004177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011192680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBC0634021.1"
                     /translation="MLKNLLNTEVVQVVEQAKDWREAVAISCRPLIENGSIEPRYVDA
                     IYRSHDTIGPYYVVGPGIAMPHARPEEGANKLSLALTLIPSGVNFDADENDPVKLLIV
                     LAATDSTSHIEAISQLAKLFDNEKDIQAILMAKTTQDILSVIARY"
     gene            11835..12866
                     /locus_tag="IRB70_004178"
     CDS             11835..12866
                     /locus_tag="IRB70_004178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000416152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBC0634022.1"
                     /translation="MEKTRKRRGTGRVTLQEVANFAGVGTMTVSRALRTPEQVSDKLR
                     EKIEQAVEELGYIPNRTAGALASGHSDTVAVLVPSLTDKASSRFMQSLQQVLNKNEFQ
                     LLLGCHEYNQLKEAEILMTLLQGNPAALVIFGSQLADKTHQILEKTNIPTINVVGSPF
                     SPAQITIETAFFEASHKLTEHLLEQGYKNIGFIGAHMDNRLQRQQLNGWHKAMLSHYQ
                     NSDLVITMPDAASLQLGRYALNEILLRQPELDAVICSHEEIALGIMFECQRRLLKIPE
                     NIAVACLDGSDNCDQTHPTLTSIRIDYKKMGIETGKLLIGLLNNNHDESEESRIVQFN
                     YQIELRQST"
     gene            12994..13516
                     /locus_tag="IRB70_004179"
                     /pseudo
     CDS             12994..13516
                     /locus_tag="IRB70_004179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907654.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
BASE COUNT         3708 a         3019 c         3127 g         3662 t
ORIGIN      
        1 tgcgccggga tttgaccaag cgtgaaagcc tgagcatggc gacaattgct cctacggctg
       61 cacgtaaccc aattccttgg cagagaaggt tacgcaatat cgcgtatctg ccgaagcgat
      121 ctcttgtgaa acgttttatg gacgacgtta tccagcccgc catgacgctg gttcaggagg
      181 aactgaacaa gcaggggacg ataagccaca ttagtgatgc agtcgacgat cgtattcgtc
      241 ttgaagtcga tttgggcaac gagctgaatt ttatatatga agtgaggctt cgcgggtata
      301 tctcaccgac cttcgcgctc gccgcaatgg ataatgatga gcagcagact gaacaacatc
      361 gatattatcg cgctgaggtt tatctcaaag aaggcggtca aaattatgat gtgatgggct
      421 ggaaccagga acagctgatt aatgacatac tggaccagta cgaaaaacat ctgcacttcc
      481 tgcacctggt tcgttaatag caacatgccg tcctgggggc ggcaattatt atcccggccg
      541 caatatgagg gaatgcagaa tgatttcacg ctggaaatgg atgctgaagc agacaattaa
      601 aaaactatgg ttcagggcaa cgttattcgc aattgtcgcg ataataacgg cccttttatc
      661 aattcttttt aaatcaatga tacctgagtc ggtttccgtg aaggttggtg cggaagcagt
      721 cgataacatt ctgaacatac tggcatcgag tatgctggca gtgaccacat tttcgctgag
      781 tatcatggtc acagcctacg gttcagccac tactaatgtg actcccagag ctacgcgttt
      841 agttgttgaa gacgtcacca cacaaaatgt actggccacc ttcatcggtt cttttctctt
      901 cagtctggta gggattattg ccctcaatat gggagcttat ggagaaaggg ggagagtcat
      961 tttattcatt gtcacactgg ttgtcattgc cttaatcctc atcacattgc ttcgctggat
     1021 acagcatttg acctctctgg ggagggttgg tgagacaacg gcacaagtag aacaggcggc
     1081 catcgaaaca tttattgcga gagcaagaaa tccctgtctc ggcggatatc catggcttga
     1141 gaacaatgaa cagccgaaag gaacggttgc agtttatccg aagaagattg gctatgttga
     1201 atatattgat atggtgaaac ttagcaagct gctgaccaat gatccccgtc atgtatacct
     1261 cgtggcgcag ccaggcagtt tcatacatcc gtccatgcca gttttgtacc tgagtcaggg
     1321 ccaggagtcg tcaatcagca ccgatttact tgagacgatt attgtctcgg atgcacgttc
     1381 atttgctcag gatcctcgat tttgtcttag cgtcatggcc gaaatagcct gccgggccct
     1441 ttcccctgca gtgaacgatc ctggaaccgc cattgatgtc attggcagag gtgttcgtat
     1501 actttccact tacgcgcaga ataaatctga tgaaatagaa gtgaaatatc cttcagtaca
     1561 tgttgcacca cttcagaata acgatctact ggaagacttt ttctcacctg tcgcgcgcga
     1621 tggtgccagt atgagggaga ttcagataag agtccttaaa ggactgtcga tgctgagtaa
     1681 aggttggcca gggatatttg ctgaagccgc acataccctg gcatttgaaa cattagagca
     1741 tgcaactcgt gctgaccata tagattctga tagatatcta ataaaatcaa cttattataa
     1801 tttatttagt ggcgaatatt ctaataaaaa aacatagctg cagagcaagc gattcggttg
     1861 ttggcaagtc aagggcaaag cattcgcgtg agaatgggcg tatgctttgt gccaaaagca
     1921 aacgttgcta attctgcact gttcagcgat ggcgcagtag cgacaggcac tgccactgtc
     1981 cagtcggcaa aagcgaacac tttgccactg cggggataaa ctgattgaag ctctcgcgca
     2041 aaatcactta ttcttttgcg ttaataaaat gtaggagatg ggtcatgaca ggcgaaaatc
     2101 gtggccgggg aaggccgcga aagacagaaa gtacctatgc agatactcgt aatgatctga
     2161 tccgcagtgg ccttgaactg ctgacgcaga atggttttct tgcgacggga gtcgatgcca
     2221 ttgttaaaaa tgccaatgtc cctaaaggct cattttatta ctactttaag agtaaagagg
     2281 attatgctca gaccgttctg aacgcctatg acagtttctt cgagcataaa ctcaaaaaac
     2341 atctacatga atcatcctgc acaccaatgg tacgtctgga aaatttcatc aatgatgcct
     2401 gtgaggggat taaaaaatac aattttaccc gcggctgcct ggttggaaat atgatgcagg
     2461 agagtccggg gcttccccaa tccttcatta aagtactaca gaatattctt gagagctggc
     2521 aggcacttgt tgcggcctgc ctgtccgacg cgttatcttc aggcgaaata agttcaaata
     2581 tgaataatac acaactggcg gctattttct ggagtggctg ggaaggtgcg gtaatgcgtt
     2641 ccaaactata ttgttctact gagccagtgt acgacttctg gagctatttc aaaacctcgg
     2701 tacgctatca gtcttctcag gaagcaacaa ctggccagta aaaggggccg cagcccctaa
     2761 aacttattat actaagcctg agctcggcat ccatctaatt agctatattg aatgactgca
     2821 cgaccgcgaa ttccgccact cagaagtttt tcagccacag tgatggcgtc actgagcgga
     2881 taaacggtag tgagactatc cattctggac tctggcaaat actataccgc ctgttgccag
     2941 attgctgctc ttttctcttt cgcgaacatg acgctatcaa tccctttcag cgtgacacca
     3001 cgcagaataa acggagccat attgcccatc aaatccatcc cctgagccat gccgcaggct
     3061 gcaacaatac tgccatatcg gaccccggcg caggcatttc tccagtaaca gggggttgta
     3121 ttgtatttta ttgtgccggt tcaggtgtgc gtttcccggc gcgtctgcac cggcttaacc
     3181 aaattcaaca gggataaaat agtgcaaata accgaagtat tacttgcaga atcgggggaa
     3241 gcatccgggg ttttattcaa caggctgtag atcactgact gcgtctgttg gccgtccact
     3301 tcacgcgtca ttcgaccaga gtaaatattg atgattacta gattcgtgta ttttatcagg
     3361 cattttactt gcgaataaat ccccttgcta tccagcgaaa ccacacaggt agctattacc
     3421 atatgtggta atacactagt tacaggaaaa atatgcaagt tccgcaatac gttgtgtgtt
     3481 gctccttagc caggatcttt tcttccatgc gagatatgac aacaattttg aggaaggatg
     3541 ttcgtaactg gtagagttac tacaacaagc atgggaggct ctgactctga cagacattgt
     3601 actgtggaat gttgttacag gttggggcgg caaccgtgcc aggagaccat gagccgttca
     3661 cggcattaaa ggccacactt cagtcgttta cattccctat ggtggcaggc atcttccatt
     3721 aaggcgtcag agcgttacca acgttatgtt gtcatggctc atctttcata gtcgatgctt
     3781 atctggtggc tgaaactagc cgcagataaa gagtgtgaag ttgataccat ggagtggagt
     3841 gacgtgcagg caggagattc gctctatgca gggttgtgag atgaattcaa accggctggc
     3901 agcgccagtg atattcgaag attcgtccgg ttgttaccca gtatgcatta aaaacccaga
     3961 cattatggac aatataacgg cttctacaac aaggaagtgc ctgtttacca tccgggtgta
     4021 atgactcacc tttatgggct tttgcccgtc gcgctcttaa cgttgaagac attctctgcc
     4081 tgccgattca ggactgcgac aaaagccata tctggctact ggtcaaggat gaccagcgtc
     4141 tggagtaggt gataagccaa atagataagc tggaatatgt ggtgaaagtg caacgtaatc
     4201 agtccaatcc gacgatgttt aacaagattg tggtgttttt tcagtaagtc attcgtcttc
     4261 tgaatcaggt gtaatgatct ttacagaacc attctggcag tgcgtaacat aatctgccgg
     4321 taacggacga tcgctaatca gaacgtcaaa tgcagagatc ggtgcgaggc tggcagaggc
     4381 cacttcatcg aacaacgcgt ggcgggcgag caaaattttc cgtagtccac ggttcatcgc
     4441 tttacgctta gtggcaagat cttcagggtt aaaccagctg acgccaaagt gattatgcac
     4501 accgctggcg gaaataaata tttttcgcgg attgagagag tctaatggcg aagagttact
     4561 ggcatcgtaa aaagcatcac ttctggcacg atacgtacca ccacaaagta ttgctgttac
     4621 attaggcttt tcattcaacg caacaaagac gcgatgtgag taacagatgc cggtgaaggt
     4681 gattgcatcc gggatcatgc ttataacgag tggtatctcc tggccattat caaagaagat
     4741 cagatcattt tcattaacca ttccggcagc cagaattgca ataggtaagt catcacgatg
     4801 attttttgga acgtcatgga ttactggcat ggatggcgcg ggtttattca ccattacaat
     4861 atagccaccc agtagggtca gtggcagagg ttcatcttcc tgatggagat cgcgacgaat
     4921 agtcattaca gaaacttcca gcattcgcgc tgcgtctttc aaatggattc tgtcggtttt
     4981 cttaagcagt tccatcaaac gtcggatacg ctctttttgc ttcgtttcca tcaactctct
     5041 ctccgtaaga atgttataaa aataacattt tggcgttagt aaacattgtt ttcattacca
     5101 tactatacga ccgacccttt gaaatgaaaa gggtataggc tgctgagttt tgggcactaa
     5161 tcttgttagg ttgcttatga ttagatagtg ttggcctgag tgatgagact ggaagtctat
     5221 taaataaaca tcgggttgat gtgctaatcg cgatctcagt cacaaatgat gcaaaagtaa
     5281 catgctaatg ttatttaaat accattgtta tgcgaaagtt tataagaggt agtgaaatgg
     5341 acattgcagt tattggttcc aatatggtgg atctcattac ttacactaat cagatgccta
     5401 aagaaggaga aactctggaa gcacctgcct tcaaaatcgg atgtggtggg aaaggtgcta
     5461 atcaagcggt ggcggcggct aaattgaatt caaaagtcct gatgctgact aaagtaggtg
     5521 atgatatttt tgcggataat actattcgta atcttgaatc atggggaatt aataccactt
     5581 atgttgagaa ggtcccctgt accagcagtg gtgttgcacc gatctttgtt aatgccaact
     5641 cgagcaatag tatattaata attaagggag cgaataaatt tctttccccg gaagatatcg
     5701 atcgagctgc agaagatctg aaaaaatgca aattgatcgt tttacaactg gaagttcaac
     5761 tggaaacagt ttaccacgcg attgagtttg gtaagaaaaa tggtattgaa gtgttattaa
     5821 atccggctcc ggcattgcgt gagttagata tgtcttatgc ctgcaaatgt gatttcttta
     5881 tcccgaatga aacagaactg gaaatattaa ccggtatgtc ggttgatact tatgatcata
     5941 ttcgtttggc cgcacgttcg ttagttgata aagggctgaa caatattatt gttaccatga
     6001 gcgaaaaagg cgcattatgg atgacccgcg atcaggaagt ccatgttcct gcattcaaag
     6061 taaatgctgt tgatactagt ggcgctggtg acgcatttat tggttgcttt tcccattatt
     6121 atgttcaaag cggtgatgtt gaagccgctt tgaaaaaagc cgctctcttt gccgctttca
     6181 gcgtcacagg gaaaggtacg caatcatctt atccgagtat tgaacaattt aatgaatttt
     6241 taaccttaaa cgaataatca tcctgcacag ttaaaggtag cactatgaac gataaaaaca
     6301 tcattcagat gcctgatgga tatctgaata agactccctt gttccagttt attttgttat
     6361 cgtgtttatt cccgctatgg ggatgcgcag ctgcattaaa tgacatatta atcactcaat
     6421 tcaaaagtgt attttcgcta agtaactttg cttcagcatt ggtgcagagc gcattttatg
     6481 gaggttattt tttaattgca ataccagcat cccttgtgat taaaaagacc agttataagg
     6541 tggcaatttt aattggcctg acgctgtata ttggtggttg tacacttttt ttccctgcct
     6601 cgcatatggc aacctacact atgttccttg cagctatttt tgcgattgcg attggcctga
     6661 gtttccttga aactgcagcg aacacataca gttcaatgat cggtccaaaa gcctatgcca
     6721 cattgcggct caatatcagc cagacctttt atccgattgg tgctgcgtct ggtattttat
     6781 tgggcaaata tctggttttc tccgaggggg aaagccttga gaagcagatg tccggaatga
     6841 acgccgagca aattcacaac tttaaggtgc tgatgttaga gaacaccctt gaaccgtata
     6901 agtatatgat tatgattctg gttgtggtca tggtgttgtt ccttttaacc cgcttcccaa
     6961 cctgtaaagt ggcacagaca agtcaccata aacgcccgtc agcaatggat acgctgcgct
     7021 atctggctaa aaattcgcgc tttcgtcgtg gtattgtggc tcaattcctt tatgtgggta
     7081 tgcaggtcgc agtatggtca tttaccatcc gtctggcact ggagttgggc gatatcaacg
     7141 aacgtgatgc ttcaaacttc atggtctata gctttgcctg cttctttatt ggcaagttta
     7201 tagccaacat ccttatgacg cgttttaatc cggaaaaagt attgattctc tattccgtta
     7261 taggggcgct gttcctggca tatgttgcac tggctccaag tttcagcgcg gtctatgtcg
     7321 ccgtcctggt aagtgttttg tttggccctt gctgggcgac gatctatgca ggaacactgg
     7381 atacagttga taacgaacat acagaaatgg caggagcagt cattgttatg gctattgtcg
     7441 gcgccgcggt ggttccggca attcagggat atattgcaga tatgttccac tcacttcagc
     7501 tttcattcct ggtttctatg ctctgctttg tctatgtcgg agtctacttc tggcgtgaaa
     7561 gcaaagtacg taatgcactg gctgaagtca cagagtcctg aggagaatcg ttatgagtac
     7621 gcgtatttat ttgtggcggg cgctttttgg cgaaaaacct cgtatcttgc tggaaaatag
     7681 tgattttact gtcacgtctt ttcgctatga cagtggtgtc gaggggctta aaattgcaaa
     7741 cagtcgtgga catttaatta ttcttccctg gatggggcag atgatttggg atgcgcaatt
     7801 tgatggacac agtctcacca tgtgcaatat gtttcgccag cctaaaccgg cgacagaggt
     7861 gatagaaacc tatggctgtt ttgcctttca ttcaggtttg ctggctaatg gctgcccatc
     7921 tgcggaagat actcatctgc tacacggtga aatggcctgt gccgcgatgg atgaagcatg
     7981 gatggaatta gagggagata tgttacgcct taccgggcgt tgcgagtatg taatggggtt
     8041 cgggcatcat tatctggctc agccaacagt ggtccttcac aaatcctcta cattgttcga
     8101 tattaagatg gccgtaacca atctggcttc tgtagatatg ccactacaat atatgtgcca
     8161 catgaattat gcatatatac caaatgctac gttcagccag aatataccgg acgaaatatt
     8221 aaggttgcgt gaatcagtac cttcgcatgt taatcccacc gctcagtggc tggcgtttaa
     8281 tcaacggatt atgcagggag aagcctctct gtcgacgctg aatcaaccgg aattttatga
     8341 tccagaaata gtcttctttg cagacaaact ggacgcttac acagatcagc cagagtttcg
     8401 catgatcgct cccgatggca ctacgtttgt tactcgtttc tccagtgccg aactaaatta
     8461 tgtgacacgc tggatccttt ataacggcga gcaacaggta gccgcctttg cattacctgc
     8521 aacctgtcgg cctgaggggt atcttgccgc gcaacgtaat ggcacgctga ttcaggttgc
     8581 accgcagcaa acacgcactt ttacagtcac cacaggaatt gaataaccac ttaaggcctg
     8641 aacagcggcg cgcttatcgt taatgtaagc gcgttttttt acccgccagg acaatactat
     8701 gatagcgttg cccttataga cgatcacatt atcgtccact ccaaatttgc gcaactactg
     8761 tagagtggtg tactccacag cttcttttag gatctcaact tccattgttt tcttaccgag
     8821 caagcactgc aactctttta tttatttgta gtggtcaaca aaaactggtc acaatttcag
     8881 attttttcca gtatctattt tccgattcgt tcggcggtaa tccaccgtta tattcatgag
     8941 gccggagtgc actataaaag tgtatgcgta aaccgactgc tgtatgtagc cattaagcct
     9001 gtattggtaa cataggtacc caccttttca acaagtggac acctgttata gaacaaaaaa
     9061 cattatcagc tgaaccccgc aggtcatttt caaatgagtt taaacttcaa atggttacac
     9121 tggctttaca accaaggggt tctgttgccc gtattgcccg ggagcatgat atcaatgata
     9181 atcttctgtt caaatggctc aggctctcgc tgatcaaagg gcgtatatca cggcgtcttc
     9241 cgttaacgaa ctcttctggc attggcgttg aattattacc tgtggagatg acgctgggat
     9301 gagcggcctt accccgtttt ttacgcgagg taattatgaa gatcaatgac tagccgtcga
     9361 accgtgtgca tgaactgctg cactgaaact tctcagctgt aaaataatcc ttacgctacg
     9421 tacttctcgg agcgcttacg attaatcgga tgcagtcctg actggaagaa agaaaaatgg
     9481 agaaaataag aggaattaat atcctccacg ttcctgaaat cctggaggat attaatgtca
     9541 tcaaaatatt agcgaacgat aatccctaac aaaataccca gtgcgccaaa gtcagcatca
     9601 ctgaaggtgg tgttagcaaa accaatatca cccagcaccg gcaataagaa tactggcagg
     9661 aaggtaataa gcaagccttg agcgaaggca cccaaaatcg caccacgacg tccacccgtt
     9721 gcattaccga atacccctgc agctgcacct acgaagaagt gcggcaccac accaggaata
     9781 atcacgatca tgttcagcag atacaacgtg aacataccga ttaaacctgc agcaaagcta
     9841 ctcaggaaac caaccagtac agcgttaggt gcgtaaggga agacgaccgg gcaatcgaga
     9901 gcaggtctgg cattcggaac cagcttgtct gaaatacctt tgaatgccgg gacaatctcc
     9961 gcaatcacca tgcgcacacc ctgcagaatg atgtacacgc cagctgcgaa ggtaatggat
    10021 tgcatgatag agaacatgaa ccagttttta ccaccgctaa gctctttcac cgcatctgca
    10081 cccgcaaaca ggcacgtcac caggaaaatt atgctcatgg taaaagagat agcaaccggc
    10141 gtgtcgcgca agaacagcag acttttcggc acattcatgt cttcagtcga gtgctcttta
    10201 ttaccaaact tgctgccgat gaaaccggcc aatacataag ataatgttga gaagtggccg
    10261 atggcaacgt catcagaacc ggtcactttc ttcatgtacg gatgcgcaat agccgggaaa
    10321 aagaccattg ccacgccaac aaccaaagag ccaacggcta taagcgtaat gccggtcatg
    10381 cctgctgttg ccagaattac cgctaccatc atcgacataa acaacgtgtg atgaccggtc
    10441 aggaagataa atttccacgg tgtgaaacgg gcaatcataa tgttgataac catcgcaaag
    10501 aacataatca tcgccatttc tttcccgaag cttttctgcg ctacggaaac aatggcttca
    10561 ttgttcggca ctacaccctg aataccaaag gcatgctgga aaatgtttgc gaagtcaccc
    10621 agtgacgaca caactaaacc cgcccctgcg cctaaaatca caaaccccat aatggtcttg
    10681 acggtacctt taatgcattc ggttaccggt tttttctgtg caatcaggcc aatcagggcg
    10741 attaaaccga ccagcactgc gggttcggaa agtacatcgc tcatcaaaaa acgaaagaaa
    10801 tccatatcgc ccccagctta cagtgcgcct aattcgttta ataccacgga taaacgttct
    10861 ctcatggctt tcttatcaat catattttcc agtgcgacga ttttgcctgc gacagactgc
    10921 gcgactaact gctcggcaat gtctttggtg ccgacataga tatcactcga cgtccctttc
    10981 gcggagccca ggtcgacgtg atcaacatca gcgctgacgg acaaatcctt caaaatgctt
    11041 ttaatgctca tttccatcat caggctggtg cctaagccgt taccgcaaac cactgtaatt
    11101 ttcataaatg ttcctctgga ttaatagcgc gcaataacag acaaaatgtc ctgcgtcgtt
    11161 ttggccatca aaatggcctg tatgtctttt tcgttatcga ataacttggc gagttgagaa
    11221 atcgcttcaa tgtggctggt actgtcggtt gcagccagca caatcagtaa tttcactgga
    11281 tcgttttcat cggcatcaaa attcacacct gaagggatca gggtcagtgc taatgacagc
    11341 ttgttagctc cctcttccgg gcgcgcatga ggcatcgcaa taccagggcc aaccacatag
    11401 tacggaccga tagtgtcgtg cgagcgatag atcgcatcaa cataacgcgg ttcgatagaa
    11461 ccgttttcaa tcaacggccg gcatgaaatc gccacggctt cccgccagtc tttggcctgt
    11521 tccacgacct gaacgacctc tgtatttaat agatttttta acatgctact gataactccc
    11581 gatgataatt aacaggagag tagatatttt acgcattaat taatgtgatg attgtcgcat
    11641 ttgatagcgc tatctgataa cgctatcaat ctttgtgata gcgctatcat ttctctgccg
    11701 ccatgctttg gctatattcg gttcctgcat atacaatgca acaggatatt tgctaccgtg
    11761 ggcaaaaact ggaaagagta atggtgaaat aaaagtaatg aaaacagctg gttgtaatta
    11821 tccatggagt cgaaatggaa aaaacacgta agcgccgtgg taccggacgg gtgacgctgc
    11881 aggaggtcgc taactttgca ggtgtcggaa ccatgaccgt ttcccgtgcg ctgagaacac
    11941 cggaacaggt atctgacaag ctgagggaaa agatagaaca ggccgtagaa gagttgggtt
    12001 atattcccaa cagaactgct ggcgcccttg catctggtca cagtgataca gtcgccgtac
    12061 tggttccttc cctgacagat aaagccagct cccgctttat gcagtcgttg cagcaggtgc
    12121 ttaataaaaa tgaattccag ctactgcttg ggtgtcatga gtataatcag ctcaaagaag
    12181 ctgaaattct gatgacgctt cttcaaggca acccggcggc gttagttatt tttggttctc
    12241 agttggctga taaaactcac cagatactcg agaaaacaaa tatacctacc attaacgttg
    12301 tcggttcccc tttcagtccg gctcaaatta ccatcgaaac agcatttttt gaagcatcac
    12361 ataaactgac cgaacatctg ctggaacagg gttataagaa tatcggattt atcggtgcgc
    12421 atatggacaa ccgcctgcaa cgtcagcaac tgaacggctg gcataaagca atgttgagcc
    12481 attaccagaa ctctgatctt gttatcacca tgccggatgc cgcaagtctg caattggggc
    12541 gttacgcatt aaacgagata ttactgcgac aaccagagct ggatgctgtg atttgcagcc
    12601 acgaagagat tgcgctgggt atcatgtttg agtgccagcg gcgtttgtta aaaattcctg
    12661 aaaatatcgc tgtagcttgt cttgatggtt cagacaattg cgatcaaaca cacccaacct
    12721 tgacatccat ccgtattgac tacaaaaaaa tggggataga gacgggtaag ttactgattg
    12781 ggctattgaa taataatcat gatgaatcag aagagtcgcg tatcgtgcaa ttcaactacc
    12841 agatagaatt acgtcagagt acatgagcct aaaagggcac tattacaaag ttagctattg
    12901 tggtagggat agccgtttcc ggctattccc cgcgcagatc cggatgtatg ctgctaacgc
    12961 atccattcct acttcaggta tttggcgtag aagcggatgc caaaaacttg ccgcaaaacc
    13021 gcaatatcag cctgcagagt cgctctccag attatccatt cctatattat ctctgcaccg
    13081 gatgaattac gcgaaccact cagaaatatg acacgtatgc aacttatcag gactccggga
    13141 tcctggaagc ctagtgccag tgaatatcgt aatgttacca acgtttatcg cattgcattg
    13201 aaatcacttg cctgacgcta tttcgagtta catgatgaaa tcgccgacct tgatgtcatg
    13261 attgcggcaa ttgtcgatga actggcacct gaactgatta aacgtaatgc tgttggatac
    13321 gaaagcgctt cgcagttgct catcactgcc ggagataatc cccaacggct aagaatagaa
    13381 tcaggttttg cggtgctgtg tggtgtcaac tcggttaccg tatcttctaa aaaaatgaac
    13441 cgttaccgac ttaatcgggg tggggagcgt gctgcaaata gtgcacttca gatcatcgct
    13501 atcggacgtt tacgaa
//
LOCUS       DADXDL010000115        13142 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.115, whole genome shotgun sequence.
ACCESSION   DADXDL010000115 DADXDL010000000
VERSION     DADXDL010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 13142)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13142)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13142
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.115"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1836)
                     /gene="ccmF"
                     /locus_tag="IRB70_004180"
     CDS             complement(<1..1836)
                     /gene="ccmF"
                     /locus_tag="IRB70_004180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type biogenesis heme lyase CcmF"
                     /protein_id="HBC0634023.1"
                     /translation="MMPEIGNGLLCLALGIALLLSVYPLWGVARGDARMMASSRLFAW
                     LLFMSVAGAFLVLVNAFVVNDFTVTYVASNSNTQLPVWYRVAATWGAHEGSLLLWVLL
                     MSGWTFAVAIFSQRIPLDIVARVLAIMGMVSVGFLLFILFTSNPFSRTLPNFPIEGRD
                     LNPLLQDPGLIFHPPLLYMGYVGFSVAFAFAIASLLSGRLDSTYARFTRPWTLAAWIF
                     LTLGIVLGSAWAYYELGWGGWWFWDPVENASFMPWLVGTALMHSLAVTEQRASFKAWT
                     LLLAISAFSLCLLGTFLVRSGVLVSVHAFASDPARGMFILAFMVLVIGGSLLLFAARG
                     HKVRSRVNNALWSRESLLLANNVLLVAAMLVVLLGTLLPLVHKQLGLGSISIGEPFFN
                     TMFTWLMVPFALLLGVGPLVRWGRDRPRKIRNLLIIAFISTLVLSLLLPWLFESKVVA
                     MTVLGLAMACWIAVLAIAEAALRISRGTKTTFSYWGMVAAHLGLAVTIVGIAFSQNYS
                     VERDVRMKSGDSVDIHEYRFTFRDVKEVTGPNWRGGVATIGVTRDGKPETVLYAEKRY
                     YNTAGSMMTEAAIDGGITRDLYAALGEELENGAWAVRLYYKPFVRW"
     gene            complement(1833..2312)
                     /gene="ccmE"
                     /locus_tag="IRB70_004181"
     CDS             complement(1833..2312)
                     /gene="ccmE"
                     /locus_tag="IRB70_004181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c maturation protein CcmE"
                     /protein_id="HBC0634024.1"
                     /translation="MNIRRKNRLWIACAVLAGLALTIGLVLYALRSNIDLFYTPGEIL
                     YGKRETQQMPEVGQRLRVGGMVMPGSVQRDPNSLKVTFTIYDAEGSVDVSYEGILPDL
                     FREGQGVVVQGELEKGNHILAKEVLAKHDENYTPPEVEKAMEANHRRPASVYKDPAS"
     gene            complement(2309..2518)
                     /gene="ccmD"
                     /locus_tag="IRB70_004182"
     CDS             complement(2309..2518)
                     /gene="ccmD"
                     /locus_tag="IRB70_004182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmD"
                     /protein_id="HBC0634025.1"
                     /translation="MTPAFASWNEFFAMGGYAFFVWLAVVMTVIPLVVLVVHSVMQHR
                     AILRGVAQQRAREARLRAAQQQEAA"
     gene            complement(2515..3252)
                     /gene="ccmC"
                     /locus_tag="IRB70_004183"
     CDS             complement(2515..3252)
                     /gene="ccmC"
                     /locus_tag="IRB70_004183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmC"
                     /protein_id="HBC0634026.1"
                     /translation="MWKTLHQLAIPPRLYQICGWFIPWLAIASVVVLTVGWIWGFGFA
                     PADYQQGNSYRIIYLHVPAAIWSMGIYASMAVAAFIGLVWQMKMANLAVAAMAPIGAV
                     FTFIALVTGSAWGKPMWGTWWVWDARLTSELVLLFLYVGVIALWHAFDDRRLAGRAAG
                     ILVLIGVVNLPIIHYSVEWWNTLHQGSTRMQQSIDPAMRSPLRWSIFGFLLLSATLTL
                     MRMRNLILLMEKRRPWVSELILKRGRK"
     gene            complement(3294..3956)
                     /gene="ccmB"
                     /locus_tag="IRB70_004184"
     CDS             complement(3294..3956)
                     /gene="ccmB"
                     /locus_tag="IRB70_004184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heme exporter protein CcmB"
                     /protein_id="HBC0634027.1"
                     /translation="MMFWRIFRLELRVAFRHSAEIANPLWFFLIVITLFPLSIGPEPQ
                     LLARIAPGIIWVAALLSSLLALERLFRDDLQDGSLEQLMLLPLPLPAVVLAKVMAHWM
                     VTGLPLLILSPLVAMLLGMDVYGWQVMALTLLLGTPTLGFLGAPGVALTVGLKRGGVL
                     LSILVLPLTIPLLIFATAAMDAASMHLPVDGYLAILGALLAGTATLSPFATAAALRIS
                     IQ"
     gene            complement(3953..4570)
                     /gene="ccmA"
                     /locus_tag="IRB70_004185"
     CDS             complement(3953..4570)
                     /gene="ccmA"
                     /locus_tag="IRB70_004185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c biogenesis heme-transporting ATPase
                     CcmA"
                     /protein_id="HBC0634028.1"
                     /translation="MLEARELLCERDERTLFSGLSFTLNAGEWVQITGSNGAGKTTLL
                     RLLTGLSRPDAGDVLWQGQPLHQVRDSYHQNLLWIGHQPGIKTRLTALENLHFYHRDG
                     DTAQCLEALAQAGLAGFEDIPVNQLSAGQQRRVALARLWLTRATLWILDEPFTAIDVN
                     GVDRLTKRMAQHTEQGGTVILTTHQPLNVAESKIRRISLTQTGAA"
     gene            complement(4589..5191)
                     /gene="napC"
                     /locus_tag="IRB70_004186"
     CDS             complement(4589..5191)
                     /gene="napC"
                     /locus_tag="IRB70_004186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome c-type protein NapC"
                     /protein_id="HBC0634029.1"
                     /translation="MGNSDRKPGLIKRLWKWWRTPSRLALGTLLLIGFVGGIVFWGGF
                     NTGMEKANTEEFCISCHEMRNTVYQEYMDSVHYNNRSGVRATCPDCHVPHEFVPKMIR
                     KLKASKELYGKIFGVIDTPQKFEAHRLTMAQNEWRRMKDNNSQECRNCHNFEYMDTTA
                     QKSVAAKMHDQAVKDGQTCIDCHKGIAHKLPDMREVEPGF"
     gene            complement(5201..5650)
                     /gene="napB"
                     /locus_tag="IRB70_004187"
     CDS             complement(5201..5650)
                     /gene="napB"
                     /locus_tag="IRB70_004187"
                     /EC_number="1.9.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrate reductase cytochrome c-type subunit"
                     /protein_id="HBC0634030.1"
                     /translation="MKSHDLKKALCQWTAMLALVVSGAVWAANGVDFSQSPEVSGTQE
                     GAIRMPKEQDRMPLNYVNQPPMIPHSVEGYQVTTNTNRCLQCHGVESYRTTGAPRISP
                     THFMDSDGKVGAEVAPRRYFCLQCHVPQADTAPIVGNTFTPSKGYGK"
     gene            complement(5647..6510)
                     /gene="napH"
                     /locus_tag="IRB70_004188"
     CDS             complement(5647..6510)
                     /gene="napH"
                     /locus_tag="IRB70_004188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinol dehydrogenase ferredoxin subunit NapH"
                     /protein_id="HBC0634031.1"
                     /translation="MANRKRDAGREALEKKGWWRSHRWLVLRRLCQFFVLGMFLSGPW
                     FGVWILHGNYSSSLLFDTVPLTDPLMTLQSLASGHLPATVALTGAVIITVLYALAGKR
                     LFCSWVCPLNPITDLANWLRRRFDLNQSATIPRHIRYVLLVVILVGSALTGTLIWEWI
                     NPVSLMGRSLVMGFGSGALLILALFLFDLLVVEHGWCGHICPVGALYGVLGSKGVITV
                     AANDRQKCNRCMDCFHVCPEPHVLRAPVLDEQSPVQVTSRDCMTCGRCVDVCSEDVFT
                     ITTRWSSGAKS"
     gene            complement(6497..7192)
                     /gene="napG"
                     /locus_tag="IRB70_004189"
     CDS             complement(6497..7192)
                     /gene="napG"
                     /locus_tag="IRB70_004189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapG"
                     /protein_id="HBC0634032.1"
                     /translation="MSRSAKPQNGRRRFLRDVVRTAGGLAAVGVALGLQQQTARASGV
                     RLRPPGAINENAFASACVRCGQCVQACPYDTLKLATLASGLSAGTPYFVARDIPCEMC
                     EDIPCAKVCPSGALDREIESIDDARMGLAVLVDQENCLNFQGLRCDVCYRECPKIDEA
                     ITLELERNTRTGKHARFLPTVHSDACTGCGKCEKVCVLEQPAIKVLPLSLAKGELGHH
                     YRFGWLEGNNGKS"
     gene            complement(7199..9685)
                     /gene="napA"
                     /locus_tag="IRB70_004190"
     CDS             complement(7199..9685)
                     /gene="napA"
                     /locus_tag="IRB70_004190"
                     /EC_number="1.7.99.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="periplasmic nitrate reductase subunit alpha"
                     /protein_id="HBC0634033.1"
                     /translation="MKLSRRSFMKANAVAAAAAAAGLSVPGVARAVVGQQEAIKWDKA
                     PCRFCGTGCGVLVGTQQGRVVACQGDPDAPVNRGLNCIKGYFLPKIMYGKDRLTQPLL
                     RMKNGKYDKEGEFTPITWDQAFDVMEEKFKTALKEKGPESIGMFGSGQWTIWEGYAAS
                     KLFKAGFRSNNIDPNARHCMASAVVGFMRTFGMDEPMGCYDDIEQADAFVLWGANMAE
                     MHPILWSRITNRRLSNQNVTVAVLSTYQHRSFELADNGIIFTPQSDLVILNYIANYII
                     QNNAINQDFFSKHVNLRKGATDIGYGLRPTHPLEKAAKNPGSDASEPMSFEDYKAFVA
                     EYTLEKTAEMTGVPKDQLEQLAQLYADPNKKVISYWTMGFNQHTRGVWANNLVYNLHL
                     LTGKISQPGCGPFSLTGQPSACGTAREVGTFAHRLPADMVVTNEKHRDICEKKWNIPS
                     GTIPAKIGLHAVAQDRALKDGKLNVYWTMCTNNMQAGPNINEERMPGWRDPRNFIIVS
                     DPYPTVSALAADLILPTAMWVEKEGAYGNAERRTQFWRQQVQAPGEAKSDLWQLVQFS
                     RRFKTEEVWPEELLAKKPELRGKTLYEVLYATPEVSKFPVSELAEDQLNDESRELGFY
                     LQKGLFEEYAWFGRGHGHDLAPFDDYHKARGLRWPVVNGKETQWRYSEGNDPYVKAGE
                     GYKFYGKPDGKAVIFALPFEPAAEAPDEEYDLWLSTGRVLEHWHTGSMTRRVPELHRA
                     FPEAVLFIHPLDAKARDLRRGDKVKVVSRRGEVISIVETRGRNRPPQGLVYMPFFDAA
                     QLVNKLTLDATDPLSKETDFKKCAVKLEKV"
     gene            complement(9682..9945)
                     /gene="napD"
                     /locus_tag="IRB70_004191"
     CDS             complement(9682..9945)
                     /gene="napD"
                     /locus_tag="IRB70_004191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperone NapD"
                     /protein_id="HBC0634034.1"
                     /translation="MHTNWQVCSLVVQAKSERISDISTQLNAFPGCEVAVSDAPSGQL
                     IVVVEAEDSETLIQTIESVRNVEGVLAVSLVYHQQEEQGEETP"
     gene            complement(9935..10429)
                     /gene="napF"
                     /locus_tag="IRB70_004192"
     CDS             complement(9935..10429)
                     /gene="napF"
                     /locus_tag="IRB70_004192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin-type protein NapF"
                     /protein_id="HBC0634035.1"
                     /translation="MKIDASRRGILTGRWRKASNGIRPPWSGDESHFLTHCTRCDACI
                     NACENNILQRGAGGYPSVNFKNNECSFCYACAQACPESLFSPRHTRAWDLQFTIGDAC
                     LAYQSVECRRCQDSCEPMAIIFRPTLSGIYQPQLNSQLCNGCGACAASCPVSAITAEY
                     LHAH"
     gene            10538..10702
                     /locus_tag="IRB70_004193"
     CDS             10538..10702
                     /locus_tag="IRB70_004193"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634036.1"
                     /translation="MHTPIGVKPVAGSKEWREAWQKRAFAHISNGYKHIYIAINSPEI
                     FLLVCFLIRI"
     gene            10837..11325
                     /gene="eco"
                     /locus_tag="IRB70_004194"
     CDS             10837..11325
                     /gene="eco"
                     /locus_tag="IRB70_004194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine protease inhibitor ecotin"
                     /protein_id="HBC0634037.1"
                     /translation="MKTILPAVLFAAFATTSAWAAESVQPLEKIAPYPQAEKGMKRQV
                     IQLTPQEDESTLKVELLIGQTLEVDCNLHRLGGKLESKTLEGWGYDYYVFDKVSSPVS
                     TMMACPDGKKEKKFVTAYLGDAGMLRYNSKLPIVVYTPDNVDVKYRIWKAEEKIDNAV
                     VR"
     gene            complement(11475..13121)
                     /gene="mqo"
                     /locus_tag="IRB70_004195"
     CDS             complement(11475..13121)
                     /gene="mqo"
                     /locus_tag="IRB70_004195"
                     /EC_number="1.1.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malate dehydrogenase (quinone)"
                     /protein_id="HBC0634038.1"
                     /translation="MKKVTAMLFSMAVGLNAVSMAAKAKASEEQETDVLLIGGGIMSA
                     TLGTYLRELEPEWSMTMVERLEGVAQESSNGWNNAGTGHSALMELNYTPQNADGSISI
                     EKAVAINEAFQISRQFWAHQVERGVLRTPRSFINTVPHMSFVWGEDNVNFLRARYAAL
                     QQSSLFRGMRYSEDHAQIKEWAPLVMEGRDPQQKVAATRTEIGTDVNYGEITRQLIAS
                     LQKKSNFSLQLSSEVRALKRNDDNTWTVTVADLKNGTAQNIRAKFVFIGAGGAALKLL
                     QESGIPEAKDYAGFPVGGQFLVSENPDVVNHHLAKVYGKASVGAPPMSVPHIDTRVLD
                     GKRVVLFGPFATFSTKFLKNGSLWDLLSSTTTSNVMPMMHVGLDNFDLVKYLVSQVML
                     SEEDRFEALKEYYPQAKKEDWRLWQAGQRVQIIKRDAEKGGVLRLGTEVVSDQQGTIA
                     ALLGASPGASTAAPIMLNLLEKVFGDRVSSPQWQATLKAIVPSYGRKLNGDVAATERE
                     LQYTSEVLGLKYDKPQAADSTPKPQLKPQPVQKEVADIAL"
BASE COUNT         3164 a         3870 c         3321 g         2787 t
ORIGIN      
        1 ccagcgaaca aacggtttgt agtaaagacg cacggcccac gcgccgtttt ccagctcttc
       61 accgagcgcg gcgtacaggt cacgcgtgat gccgccgtca atcgccgctt cggtcatcat
      121 cgacccggca gtgttgtaat aacgtttttc cgcatacagc accgtttccg gcttgccatc
      181 gcgcgttacg ccgatagtcg ccacaccgcc acgccagttc gggccagtca cctctttgac
      241 atcacggaag gtgaagcgat attcatgaat atcgacacta tcgccggact tcatgcgcac
      301 atcacgctca acgctatagt tctggctaaa ggcaatacca acaattgtca ctgccagccc
      361 caggtgagcc gccaccattc cccaataact gaaggtggtt ttcgtgccgc gtgaaatacg
      421 cagcgcagct tccgcaattg ccagcaccgc aatccagcag gccattgcca ggccgagcac
      481 cgtcatcgcc accactttgc tttcgaacag ccacggcaac agcagcgaca gcaccagcgt
      541 agagatgaag gcgataatca acaaattgcg gattttacgt gggcgatcgc gcccccagcg
      601 caccagagga ccgacaccaa gcagcagcgc aaacggcacc atcagccagg taaacatggt
      661 gttgaagaac ggttcgccaa tcgaaatact gcccagtccc agttgcttgt gcaccagcgg
      721 cagcagcgtc cccagcaaca ccaccagcat cgcggcgacc agcaaaacgt tgttcgctaa
      781 caacagagat tcccgcgacc acagcgcatt gtttacgcgt gagcgaactt tgtgtccacg
      841 cgcggcaaac agcagcagcg aaccaccaat caccagtacc ataaaggcga ggataaacat
      901 accgcgtgcc ggatcagagg caaacgcgtg taccgatacc agcacgccgg aacgcaccag
      961 gaaagtcccc agcagacaca acgagaaggc actgattgcc agcagtaatg tccacgcttt
     1021 gaagctggcg cgttgttcag tgaccgccag tgagtgcatc agcgcagtcc ccaccagcca
     1081 cggcataaac gaggcgtttt ctaccggatc ccagaaccac cagccgcccc agccgagttc
     1141 gtaataggcc catgcggaac cgagcacaat gccgagcgtc aagaagatcc acgccgccag
     1201 cgtccacgga cgagtaaaac gcgcataagt gctgtccaga cgcccgctca acaaagaagc
     1261 aatggcaaaa gcaaacgcca ccgagaagcc gacgtacccc atataaagca gaggcggatg
     1321 gaagatcagc cccggatcct gtaacagcgg gttaagatcg cgaccttcaa tcgggaagtt
     1381 cggcaacgtg cgtgagaacg ggttagaggt aaagagaatg aacagcaaaa agccgacgct
     1441 gaccatcccc attatcgcca gtacgcgggc cacaatatcc agcggaatac gctgactaaa
     1501 aatcgctacc gcaaaggtcc agccgctcat cagcagcacc cacagcagga gcgagccttc
     1561 atgcgcgccc caggtagccg ccacgcgata ccacaccgga agctgggtat tggagttgct
     1621 ggcaacatag gtgacggtga agtcgttgac cacgaaggca ttgaccagta ccagaaatgc
     1681 gccagccaca gacataaaca gcagccaggc aaacaagcgg gaagacgcca tcatgcgcgc
     1741 atctccgcgc gctacgcccc atagcggata cacggacagc agcagcgcaa ttcctagcgc
     1801 cagacacagc agcccgttac caatttccgg catcatgatg ctgggtcctt ataaacactc
     1861 gccgggcgac ggtgattggc ttccatcgct ttctcaactt ctggtggcgt gtagttttcg
     1921 tcgtgtttcg ccagcacttc tttcgcgagg atatgattgc ctttttccag ttcgccctgc
     1981 accacaacgc cctgcccttc acggaacaga tccggcaaaa tgccttcgta agagacatct
     2041 actgaacctt cagcgtcgta aatggtgaaa gttactttta gcgaattggg atcgcgctgc
     2101 acactacccg gcatcaccat cccgccaacg cgcagacgct gaccgacttc cggcatttgc
     2161 tgagtttcac gcttgccgta gagaatttcc cccggcgtat aaaagagatc gatattcgag
     2221 cgcagcgcat atagcaccag accgatagtc agcgccagcc ccgccaaaac ggcacaggca
     2281 atccacaagc ggtttttacg gcgaatattc atgcagcctc ctgctgttgc gcagcacgta
     2341 aacgcgcctc acgcgcccgc tgttgcgcca cgccacgcag aattgcgcga tgctgcatca
     2401 ccgagtgcac gaccaaaacc accagaggaa tgacggtcat caccaccgcc agccagacaa
     2461 aaaaggcgta accgcccatt gcgaaaaatt cattccagga agcaaatgca ggggtcattt
     2521 acggcctctt ttcagtatca gttcactcac ccacggacgg cgtttttcca tcagcaaaat
     2581 caaattacgc atccgcatca gcgtcagcgt ggcagacagg agcaggaagc caaaaatcga
     2641 ccagcgcagc ggcgaacgca tcgccggatc gatactttgc tgcatccgcg ttgatccctg
     2701 atgcagggtg ttccaccact ccacggagta atgaataatc ggcagattca ccacgccaat
     2761 cagcaccaga atacctgcag cacggcccgc cagacggcgg tcgtcgaagg cgtgccacag
     2821 ggcaatgaca ccaacataca aaaacagcag caccagttca gaagtcagac gtgcatccca
     2881 tacccaccag gtgccccaca tcggttttcc ccatgcagag ccggtaacca gggcaataaa
     2941 ggtaaacacg gcaccaatgg gggccatcgc cgccaccgcc aggttggcca ttttcatctg
     3001 ccagacaagg ccaataaacg ccgccaccgc cattgatgca taaatgccca tcgaccagat
     3061 cgccgcaggc acatgcaggt agataatgcg gtagctattt ccctgctgat aatcagccgg
     3121 agcaaagccg aatccccaga tccagccgac ggtaagcacg accacactgg caattgccag
     3181 ccacggtata aaccagccac agatttgata cagccgtggt gggatcgcca gttgatgcag
     3241 tgttttccac atagtttcga taccagactc gaacaaaaat cagtaatcca gcgttattga
     3301 atgctgattc gtaacgctgc cgccgtcgca aaaggactta aagtcgcggt gcctgccagc
     3361 aacgcgccta aaattgccag atacccatca acgggcaaat gcatagaagc cgcgtccatc
     3421 gcggcggtgg caaagatgag taatgggata gtcagcggta acaccaatat gctgagcagc
     3481 acaccaccgc gcttaagtcc cactgtcagc gccacgcccg gtgcaccgag aaagccaagc
     3541 gtaggggttc ccagcagcag cgtcagcgcc atcacttgcc agccataaac atccattccc
     3601 agtagcattg ctaccagggg cgaaaggatg agtaacggca gaccggttac catccagtgc
     3661 gccatcacct tcgccagcac aacggcgggc aagggtaacg gcaacaacat caattgttca
     3721 agactgccgt cctgcaaatc gtcacggaac aatcgttcca gcgccagcaa ggatgaaagc
     3781 agcgcagcaa cccagataat gcccggtgca atacgcgcca gcagttgcgg ctccggaccg
     3841 atactgagcg gaaaaagggt aatgacaatc aggaagaacc acagcgggtt ggcgatttcg
     3901 gcgctatggc gaaacgctac gcgcagctca agacggaaaa tgcgccagaa catcatgcgg
     3961 cccccgtttg cgtcagtgaa atgcggcgaa ttttactttc agcaacgttg agcggctggt
     4021 gggtagtcag aatcacagtc cccccctgct ccgtatgctg cgccatacgc ttggtcagac
     4081 gatcgacgcc gttaacgtca atcgcggtaa aaggctcgtc gagtatccat aacgtggcac
     4141 gggtcagcca cagacgcgct aaagcgacgc ggcgttgttg cccggcagaa agttgattta
     4201 ccggaatatc ttcgaatccg gcaagcccag cctgcgccag ggcttccaga cattgtgcgg
     4261 tatcgccatc gcgatgataa aagtgcagat tttctaacgc cgtcagccgg gttttgatcc
     4321 ccggctgatg gcctatccat aacaggtttt gatggtagct gtcgcgtacc tgatgcaagg
     4381 gctgcccttg ccagagaacg tcacccgcat cagggcgaga caaccccgtc agcaaacgga
     4441 gaagcgttgt cttccccgcg ccgttgctac cggtgatttg tacccactct cctgcgttca
     4501 gcgtaaatga caagccacta aataaggttc gttcatcccg ctcgcaaagt aactctctgg
     4561 cttcaagcat acccacgcaa taaccctgtt aaaaacctgg ctcgacttcg cgcatatcgg
     4621 gcagcttgtg cgctatccct ttatggcaat caatacaggt ttgcccatct ttcaccgcct
     4681 ggtcatgcat cttcgcggca actgatttct gggcggttgt atccatatac tcgaagttgt
     4741 gacagttacg gcactcctgc gagttattgt ccttcatgcg ccgccactca ttctgtgcca
     4801 tcgtcaggcg atgagcttca aatttctgcg gcgtgtcaat aacgccaaaa attttaccat
     4861 acagctcttt acttgctttg agcttgcgta tcatcttcgg cacaaactcg tgcggaacgt
     4921 gacaatccgg acaggtcgca cgaacgccgc tacggttgtt gtagtgcacg gaatccatgt
     4981 attcctgata caccgtgtta cgcatttcgt ggcagctaat gcagaactct tcggtattgg
     5041 ctttttccat cccggtgtta aagccgcccc agaagacgat accgccgaca aaaccgatca
     5101 acagcagcgt ccccagcgcc agacggctgg gggtacgcca ccatttccac aggcgcttaa
     5161 tcagaccagg cttacggtca gaatttccca taataacctc ttatttcccg taaccttttg
     5221 atggggtaaa ggtattcccc acgattggcg cggtatcggc ctgcggtacg tgacattgca
     5281 gacagaaata acgacgcgga gccacttccg cgcccacttt gccgtcgctg tccataaagt
     5341 gagtaggact aatgcgcggc gcgccagtgg tgcgatagct ttcgacaccg tggcactgca
     5401 agcagcggtt ggtattggtc gttacctgat aaccttcaac gctatgcggg atcattggcg
     5461 gctgattcac atagttcagc ggcatccgat cctgctcttt tggcatccga atggcccctt
     5521 cctgcgtccc ggatacttcc ggcgactggc taaaatcgac gccattagcc gcccaaaccg
     5581 cgccgcttac caccagggcc agcatcgccg tccattgaca cagcgctttc ttcaggtcat
     5641 ggcttttcat gatttcgctc ccgaactcca tcgtgtagtt attgtaaata catcctcaga
     5701 acagacatcc acgcagcgac cgcacgtcat gcaatcgcgg ctggtgacct gcaccgggct
     5761 ttgttcatcc agcaccgggg cacgtagcac atgcggttcc gggcaaacat gaaaacaatc
     5821 catacagcgg ttacatttct gccgatcgtt ggcagcaacg gtaatcacac ctttgctacc
     5881 cagcacgcca tacagcgcgc caaccggaca aatgtgcccg caccagccgt gttcaacgac
     5941 cagtagatca aataaaaaca gcgcgagaat aagcagcgcg ccgctgccga atcccattac
     6001 cagactgcgc cccatcaggg aaacggggtt gatccattcc cagatgagcg tgccggttaa
     6061 ggccgatccc accagaatga ccaccaacaa cacgtagcga atgtggcgtg ggatcgtcgc
     6121 agactgattg aggtcaaagc gcctgcgtaa ccagttcgct aagtcggtaa tcgggttcag
     6181 cgggcagacc cagctgcaaa ataatcgctt tcctgccagg gcgtagagca cggtgataat
     6241 caccgcacca gtcagcgcta ccgtggcagg cagatgaccg ctggcaaggc tttgcagcgt
     6301 catcagcgga tcggtcagcg gaacggtgtc gaataacagg ctactgctgt agttgccgtg
     6361 caagatccac acaccaaacc acggaccgct caaaaacatc cccagcacga agaactgaca
     6421 aaggcgacgt aacactaacc aacggtgact gcgccaccag ccttttttct ccagcgcctc
     6481 gcgcccggcg tcacgtttac gatttgccat tgttcccctc cagccagccg aagcggtaat
     6541 ggtgacctaa ctcccctttc gctagtgaca gcggtaacac cttgattgcc ggttgttcca
     6601 gcacgcacac tttttcgcac ttaccgcaac cggtacaggc gtcgctgtga accgtcggca
     6661 gaaagcgggc gtgcttaccg gtacgcgtgt tgcgctccag ctccagggtg atggcctcat
     6721 caattttcgg gcattcgcga taacaaacat cgcagcgcag cccctgaaag ttgagacagt
     6781 tttcctggtc caccagcacc gccagcccca tccgcgcgtc gtcgatcgat tcgatctcac
     6841 gatccagcgc accgctcggg cacactttgg cgcacggaat gtcctcacac atttcgcaag
     6901 gaatatcccg cgcaacaaaa tatggcgtgc ccgccgacag gcctgaggcc agcgtcgcca
     6961 gttttaaggt gtcgtaaggg caagcctgaa cacactgacc gcaacgcaca caggcactgg
     7021 caaaggcgtt ctcgtttatg gctccgggcg ggcgcaaccg cacgccagat gcgcgtgcgg
     7081 tttgctgttg taaccccagc gccacaccca cggcagccag cccgcctgct gtgcgaacaa
     7141 catcgcgcag aaagcggcgg cgaccatttt gaggtttcgc tgaccgggac ataatggctt
     7201 acaccttctc cagtttgacc gcgcacttct tgaagtccgt ctctttcgag agcggatcgg
     7261 tcgcgtccag cgtcagtttg ttaaccagct gtgcggcatc gaagaacggc atgtacacca
     7321 ggccctgtgg cggacggtta cgaccgcgcg tttcgacaat cgagatcact tcgccacggc
     7381 gagaaactac tttcactttg tcgccacggc gcagatcgcg cgctttcgca tccagcgggt
     7441 gaataaacag aaccgcttcc gggaaggcac ggtgcagttc cggcacacgg cgagtcatac
     7501 tgccggtgtg ccagtgctcc aggacgcgtc cggtagagag ccacaggtcg tactcttcat
     7561 ccggtgcttc cgccgccggt tcgaacggca gcgcgaagat caccgcttta ccatccggtt
     7621 taccgtagaa cttatagcct tcgcccgctt tcacgtacgg gtcgttacct tcgctgtaac
     7681 gccactgcgt ttctttaccg ttcaccaccg gccagcgcag accgcgcgct ttgtggtagt
     7741 catcgaacgg tgccagatcg tgaccgtgac cgcgaccaaa ccatgcgtat tcttcgaaca
     7801 gccctttttg cagatagaag cccagctcgc gggattcatc gttcagctga tcttccgcca
     7861 gttcggatac cgggaatttg ctcacttccg gggtggcata cagaacttcg tacagcgttt
     7921 tgccacgcag ttccggtttc ttcgccagca gctcttccgg ccatacttct tcagttttaa
     7981 agcggcggga gaactggact aactgccaga gatccgattt cgcttcgccc ggtgcctgta
     8041 cctgctgacg ccagaactga gtacggcgtt cggcgttacc gtaagcgccc tctttctcta
     8101 cccacattgc ggtcggcagg atcaagtcgg cggccagcgc actgactgtc ggatacggat
     8161 cggaaacgat gatgaagttg cgcggatcgc gccagcccgg catacgctct tcattaatgt
     8221 tcggtccggc ctgcatgtta ttggtacaca tggtccagta aacattcagt ttgccgtctt
     8281 tcagcgcacg gtcttgtgcc accgcgtgca gaccgatttt cgccggaatg gtgccactcg
     8341 ggatattcca cttcttctcg caaatatcac gatgtttctc gttagtcacc accatgtccg
     8401 caggcagacg gtgagcaaag gtgcccactt cacgcgcagt accacacgcg gaaggctgcc
     8461 cggtcaggga gaacggaccg caacccggct gggaaatttt gccggtcagc aggtgcaggt
     8521 tgtagaccag gttgttggcc cacacgccac gagtatgctg gttgaagccc atcgtccagt
     8581 aggagatgac tttcttgttc ggatcggcat acagctgcgc cagttgttct aactggtctt
     8641 tcggcacgcc ggtcatttcg gcagtttttt ccagcgtata ctcagcaacg aaggctttgt
     8701 aatcttcaaa gctcatcggt tcggaggcgt cagaacctgg attcttcgct gctttttcca
     8761 gtggatgggt cggacgtaaa ccgtagccga tgtccgtcgc ccctttgcgc aggttaacgt
     8821 gtttgctaaa gaagtcctga tttatcgcat tgttttgaat gatatagttg gcgatgtagt
     8881 tcaggatcac caggtctgat tgcggcgtaa agatgatgcc gttatccgcc agctcgaagc
     8941 tacgatgctg gtaggtagaa agcaccgcca cggtaacgtt ctggttagag agacgacggt
     9001 tagtgatgcg cgaccagagg atcgggtgca tctccgccat gtttgcgccc cacagcacaa
     9061 acgcgtcagc ctgctcgatg tcgtcatagc agcccatcgg ctcatccata ccaaaggtac
     9121 gcataaagcc aactactgcc gacgccatac agtgacgcgc gttcgggtcg atgttgttcg
     9181 aacggaagcc cgctttaaac agcttggacg cggcataacc ttcccagata gtccactgac
     9241 cagaaccgaa cataccgatc gattccggcc ctttttcttt cagggcggtt ttgaatttct
     9301 cttccatcac atcgaaggct tgatcccagg tgattggggt aaattcgcct tctttgtcat
     9361 atttaccgtt tttcatacgc agcagcggct gcgtcaaacg gtctttaccg tacatgattt
     9421 tgggcaggaa atagccctta atgcagttca ggccacggtt aaccggtgca tccgggtcgc
     9481 cctgacaggc caccacacgc ccctgctgcg ttccgaccag aacgccgcaa ccagtaccgc
     9541 agaaacggca cggcgcttta tcccatttaa tggcttcctg ctgaccaaca acggcgcggg
     9601 caacgcccgg cacgctgaga ccggcagccg ccgcagcggc cgcaacggcg ttagctttca
     9661 taaagctacg acgactgagt ttcatggtgt ttcctcacct tgctcttcct gctggtgata
     9721 aaccagcgac accgccagca cgccctctac gttgcgtact gactcaatgg tttgaatcag
     9781 cgtttcgctg tcttctgctt ccaccaccac aatcaactga ccgctcggcg cgtcgctgac
     9841 agcaacttca cagccgggaa aggcgttcag ttgggtgctg atgtctgaaa ttcgttcgct
     9901 tttggcctgc acgaccagac tgcaaacttg ccagttagtg tgcatggaga tactccgcag
     9961 ttatggctga taccggacag ctggctgcac atgctccaca tccgttgcaa agttggctat
    10021 taagttgcgg ctggtagatc ccggagagcg tcgggcgaaa gataattgcc attggctcac
    10081 agctatcctg acagcggcgg cattcaactg actgatacgc caggcacgcg tccccaatgg
    10141 tgaactgcaa atcccaggcc ctggtgtggc gcggagaaaa tagcgattcg gggcaagcct
    10201 gcgcgcaggc gtaacagaag ctgcactcgt tatttttgaa attaacgctc ggatagccac
    10261 ccgcgccgcg ttgcagaatg ttgttttcac aagcattaat acaggcgtcg cagcgggtgc
    10321 aatgggtcag aaaatgagat tcatcaccgg accagggcgg acggataccg ttactggctt
    10381 tgcgccagcg accagtgagt atgccccgac gggatgcatc aatcttcaca ttgaccttcc
    10441 atcattaacg cgctctgaaa attgagagcg accaaataaa ccgcataatt aataagccat
    10501 ttttatagcc gctaagatat taaaggatgt gtcaaagatg cataccccga tcggggtaaa
    10561 acctgtagca ggatcaaaag agtggcggga agcgtggcaa aaacgggctt ttgctcacat
    10621 ttcaaatggt tataaacata tttatatagc gattaattcg ccagagatat ttctgctggt
    10681 ttgttttctc atcagaattt aacactaaaa gagcaggtaa aattatctga atgttcttta
    10741 agttattcat aaagcaaatt aataaatctg atgaatatgt taaccttcag cgacatcatc
    10801 ggtgaaaacc tataaatgaa gaaggaaagc aaaaaaatga agaccattct acctgcagta
    10861 ttgtttgccg ctttcgccac cacttccgcc tgggcggcag aaagcgtcca gccgctggaa
    10921 aaaatcgcac cttatccaca agctgaaaaa ggcatgaagc gtcaggtgat tcagttaact
    10981 ccgcaagaag atgaatctac cctgaaagta gaactgttaa tcggtcagac gctggaagtc
    11041 gattgcaatt tgcatcgtct cggcgggaag ctggaaagca aaacgctgga aggctggggc
    11101 tatgattatt atgtctttga taaagttagc tcgccggttt ccacgatgat ggcctgcccg
    11161 gatggcaaga aagagaagaa atttgtcacc gcgtatctgg gcgatgccgg aatgctgcgt
    11221 tataacagca agctgccgat cgtggtgtat acgccagaca atgtggatgt gaagtaccgc
    11281 atctggaagg cggaagagaa aattgacaac gcggttgttc gctaaactac tgtgaagtgc
    11341 tgcaacccgt aggccgaata aggcggttac gctgcatccg acatctaacg cccgagccgg
    11401 ttgcctgatg cgacgctgac gcgtcttatt agcatacgcc acatccggca aaccatgccg
    11461 gatgtggcac atcattacaa cgcaatatcc gccacttctt tttgaacggg ttgcggtttc
    11521 aactgcggtt tcggcgtact atctgctgcc tgcggcttgt cgtatttcag ccccagcact
    11581 tcgctggtgt actgcaactc gcgttctgtt gccgctacat caccgttcag cttgcgtcca
    11641 taagacggaa cgatcgcctt caacgttgcc tgccattgcg ggctggaaac gcgatcgcca
    11701 aatacttttt ccagcagatt caacataatc ggcgcggcgg ttgacgcacc tggcgatgcc
    11761 cccagcagcg cggcaatagt cccttgctgg tcgctgacca cttcggtacc cagacgcagt
    11821 acgccacctt tctcggcatc acgcttgata atctgtacgc gctgccccgc ttgccacaaa
    11881 cgccagtcct cttttttcgc ctgcggatag tactctttca acgcttcaaa acgatcctct
    11941 tcactcaaca tcacctgact caccagatat ttcaccagat cgaaattatc cagcccgacg
    12001 tgcatcatcg gcatcacgtt agaagtagta gtggaactca gcagatccca cagtgaacca
    12061 tttttgagga atttagttga gaaggtggca aatggcccaa acaacacgac gcgtttaccg
    12121 tccagcacac gggtatcgat atgcggaacc gacatcggtg gtgcgccaac ggatgcttta
    12181 ccgtaaacct tcgccagatg gtgattaacc acgtccgggt tttccgaaac aaggaactgt
    12241 ccgcccaccg ggaaaccggc gtagtctttc gcttccggaa tccccgattc ctgtaacagc
    12301 ttcagcgccg caccgcccgc gccgataaag acaaatttgg cgcggatgtt ctgtgcagtg
    12361 ccatttttca gatcggcaac ggtaactgtc caggtgttat cgtcattacg ctttagggcg
    12421 cggacttcgc tgctgagttg cagcgaaaaa ttagatttct tctgcaagga agcaattaac
    12481 tggcgggtga tctcgccata gttcacatca gtgccaattt ccgtacgcgt ggctgccact
    12541 ttctgttgcg gatcgcgccc ttccatcact aacggtgccc actctttgat ctgcgcgtga
    12601 tcttcagagt aacgcatacc gcgaaacagc gagctttgtt gcaacgcggc gtaacgggct
    12661 cgcaggaaat taacattatc ctcgccccag acaaagctca tatgcggaac ggtattgata
    12721 aatgaacgcg gtgtacgcag cacgccgcgc tcgacctggt gcgcccagaa ctggcgcgaa
    12781 atctgaaatg cttcgttaat ggcgactgct ttttcaatac tgatgctgcc atcggcgttt
    12841 tgcggggtgt agttcagttc catcagtgca gaatgcccgg ttccggcgtt gttccagccg
    12901 ttcgaactct cctgcgcgac accctccagg cgctccacca tggtcatcga ccattcaggc
    12961 tccagctcgc gtaaataggt ccccaacgtg gcgctcataa tgccgccgcc aatcaacagt
    13021 acatcagttt cctgctcctc ggacgctttc gcttttgccg ccatcgaaac ggcattaagc
    13081 cccacggcca tcgagaagag catggcagtc acttttttca tcttgttaat gccttacttt
    13141 ta
//
LOCUS       DADXDL010000116        12947 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.116, whole genome shotgun sequence.
ACCESSION   DADXDL010000116 DADXDL010000000
VERSION     DADXDL010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12947)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12947)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12947
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.116"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(192..449)
                     /locus_tag="IRB70_004196"
     CDS             complement(192..449)
                     /locus_tag="IRB70_004196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634039.1"
                     /translation="MQKPLSVRWLIIQGLTENEHCGIQAYACNTESQEDLYAEVPLVG
                     RLTGIEEVKVEAIAMSKLHNMSCPPYMGHSAAVIFHLIYLS"
     gene            572..2770
                     /gene="speF"
                     /locus_tag="IRB70_004197"
     CDS             572..2770
                     /gene="speF"
                     /locus_tag="IRB70_004197"
                     /EC_number="4.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine decarboxylase SpeF"
                     /protein_id="HBC0634040.1"
                     /translation="MSKLKIAVSDSCPDCFTTQRECIYINENSNIDVAAIVLSLNDVT
                     RGKLDEIDATGYGIPVFIATENQERVPAEYLPRISGVFENCESRREFYGRQLETAASH
                     YETQLRPPFFRALVDYVNQGNSAFDCPGHQGGEFFRRHPAGNQFVEYFGEALFRADLC
                     NADVAMGDLLIHEGAPCIAQQHAAKVFNADKTYFVLNGTSSSNKVVLNALLTPGDLVL
                     FDRNNHKSNHHGALLQAGATPVYLETARNPYGFIGGIDAHCFEENYLRELITEVAPQR
                     AKEARPFRLAVIQLGTYDGTIYNARQVVDKMGHLCDYILFDSAWVGYEQFIPMMADCS
                     PLLLDLNENDPGILVTQSVHKQQAGFSQTSQIHKKDSHIKGQQRYVPHKRMNNAFMMH
                     ASTSPFYPLFAALDINAKMHEGVSGRNMWMDCVVNGINARKLILDNCQHIRPFVPELV
                     DGKPWQSYETAQIAVDLRFFQFVPGEHWHSFEGYAENQYFVDPCKLLLTTPGIDARNG
                     EYEAFGVPATILANFLRENGVVPEKCDLNSILFLLTPAEDMAKLQQLAALLVRFEKLL
                     ESDAPLSEVLPSIYKQHEERYTGYTLRQLCQEMHDLYARHNVKQLQKEMFRKEHFPRV
                     SMNPQEANYAYLRGEVELVRLPDAEGRIAAEGALPYPPGVLCVVPGEIWGGAVLRYFS
                     ALEEGINLLPGFAPELQGVYIEEHDGRKQVWCYVIKPRGAQSTLLKGEKL"
     gene            2767..4086
                     /gene="potE"
                     /locus_tag="IRB70_004198"
     CDS             2767..4086
                     /gene="potE"
                     /locus_tag="IRB70_004198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putrescine-ornithine antiporter"
                     /protein_id="HBC0634041.1"
                     /translation="MSQAKSNKMGVVQLTILTMVNMMGSGIIMLPTKLAEVGTISIIS
                     WLVTAVGSMALAWAFAKCGMFSRKSGGMGGYAEYAFGKSGNFMANYTYGVSLLIANVA
                     IAISAVGYGTELLGASLSPVQIGLATIGVLWICTVANFGGARITGQISSITVWGVIIP
                     VVGLCIIGWFWFSPTLYANSWNPHHVPFFSAVGSSIAMTLWAFLGLESACANAEVVEN
                     PERNVPIAVLGGTLGAAVIYIVSTNVIAGIVPNMELANSTAPFGLAFAQMFTPGVGKV
                     IMALMVMSCCGSLLGWQFTIAQVFKSSADEGYFPKIFSRVSKVDAPVQGMLTIVIIQS
                     GLSLMTISPSLNSQFNVLVNLAVVTNIIPYILSMAALVIIQQVANVPPSKAKVANFVA
                     FVGAMYSFYALYSSGEEAMLYGSIVTFLGWTLYGLVSPRFELKNKHG"
     gene            4435..5085
                     /locus_tag="IRB70_004199"
     CDS             4435..5085
                     /locus_tag="IRB70_004199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001208812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2625 domain-containing protein"
                     /protein_id="HBC0634042.1"
                     /translation="MREVSQLVNTEDSAWPIIQNWLKEATNHAELLPVNKDLAETALY
                     QLQVTTKSPMGALVYGSGGLLIDNGWLRIAGSGHPRLPRDPASWTQRPEFASVRALPI
                     ADDVAGGIFALNGGDLGEDTGCVYYFAPDTLNWESLEVGYSEFLQWALSGDLDTFYEN
                     VRWPQWQEDVIKLSATEAFTFYPFLWVQCEEARTRKVISLTELWEMQYQMKETITQ"
     gene            complement(5126..5620)
                     /locus_tag="IRB70_004200"
     CDS             complement(5126..5620)
                     /locus_tag="IRB70_004200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634043.1"
                     /translation="MKTKRSLVVRVALITATLLLTACAQPEQSSLAGDWLLTPKDKTR
                     GLTGSIAVNIAPSRCKTNCRGDNLPDNTRRWQLSGGNEKELTYLHDMSAQEKTGLNPE
                     WQCYTSFFMGICQGKPGTRPIVNEDYVSESGFFGSMMHVGIIELRRCQSENCQQELKA
                     INTH"
     gene            complement(5825..7465)
                     /gene="pgm"
                     /locus_tag="IRB70_004201"
     CDS             complement(5825..7465)
                     /gene="pgm"
                     /locus_tag="IRB70_004201"
                     /EC_number="5.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-D-glucose phosphate-specific
                     phosphoglucomutase"
                     /protein_id="HBC0634044.1"
                     /translation="MAIHNRAGQPAQQSDLINVAQLTAQYYVLKPEAGNAEHAVKFGT
                     SGHRGSAARHSFNEPHILAIAQAIAEERAKNGITGPCYVGKDTHALSEPAFISVLEVL
                     AANGVDVIVQENNGFTPTPAVSNAILVHNKKGGPLADGIVITPSHNPPEDGGIKYNPP
                     NGGPADTNVTKVVEDRANALMADGLKGVKRISLDEAMASGHVKEQDLVQPFVEGLADI
                     VDMAAIQKAGLTLGVDPLGGSGIEYWKRIGEYYNLNLTIVNDQVDQTFRFMHLDKDGA
                     IRMDCSSECAMAGLLALRDKFDLAFANDPDYDRHGIVTPAGLMNPNHYLAVAINYLFQ
                     HRPQWGKDVAVGKTLVSSAMIDRVVNDLGRRLVEVPVGFKWFVDGLFDGSFGFGGEES
                     AGASFLRFDGTPWSTDKDGIIMCLLAAEITAVTGKNPQEHYNELAKRFGAPSYNRLQA
                     AATSAQKAALSKLSPEMVSASTLAGDPITARLTAAPGNGASIGGLKVMTDNGWFAARP
                     SGTEDAYKIYCESFLGEEHRKQIEKEAVEIVSEVLKNA"
     gene            complement(7491..8036)
                     /gene="seqA"
                     /locus_tag="IRB70_004202"
     CDS             complement(7491..8036)
                     /gene="seqA"
                     /locus_tag="IRB70_004202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation negative regulator SeqA"
                     /protein_id="HBC0634045.1"
                     /translation="MKTIEVDDELYSYIASHTKHIGESASDILRRMLKFSAASQPAAP
                     VTKEVRVASPAIVEAKPVKTIKDKVRAMRELLLSDEYAEQKRAVNRFMLLLSTLYSLD
                     AQAFAEATESLHGRTRVYFAADEQTLLKNGNQTKPKHVPGTPYWVITNTNTGRKCSMI
                     EHIMQSMQFPAELIEKVCGTI"
     gene            8221..8985
                     /gene="ybfF"
                     /locus_tag="IRB70_004203"
     CDS             8221..8985
                     /gene="ybfF"
                     /locus_tag="IRB70_004203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBC0634046.1"
                     /translation="MKLNIRAQTAQNQHNNSPIVLVHGLFGSLDNLGVLARDLVNDHN
                     IIQVDMRNHGLSPRDPVMNYPAMAQDLVDTLDAQQIDKATFIGHSMGGKAVMALTALA
                     PDRIDKLVAIDIAPVDYHVRRHDEIFAAINAVSESDAQTRQQAAAIMRQHLNEEGVIQ
                     FLLKSFVDGEWRFNVPVLWDQYPHIVGWEKIPAWDHPTLFIPGGNSPYVSEQYRDDLL
                     AQFPQARAHVIAGAGHWVHAEKPDAVLRAIRRYLND"
     gene            9125..9418
                     /gene="ybfE"
                     /locus_tag="IRB70_004204"
     CDS             9125..9418
                     /gene="ybfE"
                     /locus_tag="IRB70_004204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415211.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA regulated protein"
                     /protein_id="HBC0634047.1"
                     /translation="MAKEQTDRTTLDLFAHERRPGRPKTNPLSRDEQLRINKRNQLKR
                     DKVRGLKRVELKLNAEAVEALNELAESRNMSRSELIEEMLMQQLAALRSQGIV"
     gene            9558..10088
                     /gene="fldA"
                     /locus_tag="IRB70_004205"
     CDS             9558..10088
                     /gene="fldA"
                     /locus_tag="IRB70_004205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin FldA"
                     /protein_id="HBC0634048.1"
                     /translation="MAITGIFFGSDTGNTENIAKMIQKQLGKDVADVHDIAKSSKEDL
                     EAYDILLLGIPTWYYGEAQCDWDDFFPTLEEIDFNGKLVALFGCGDQEDYAEYFCDAL
                     GTIRDIIEPRGATIVGHWPTAGYHFEASKGLADDDHFVGLAIDEDRQPELTAERVEKW
                     VKQISEELHLDEILNA"
     gene            10298..10384
                     /gene="uof"
                     /locus_tag="IRB70_004206"
     CDS             10298..10384
                     /gene="uof"
                     /locus_tag="IRB70_004206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001491546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fur leader peptide"
                     /protein_id="HBC0634049.1"
                     /translation="MIRIISRANSVTSSNEVNRLVTGQIPHD"
     gene            10377..10823
                     /gene="fur"
                     /locus_tag="IRB70_004207"
     CDS             10377..10823
                     /gene="fur"
                     /locus_tag="IRB70_004207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric iron uptake transcriptional regulator"
                     /protein_id="HBC0634050.1"
                     /translation="MTDNNTALKKAGLKVTLPRLKILEVLQEPDNHHVSAEDLYKRLI
                     DMGEEIGLATVYRVLNQFDDAGIVTRHNFEGGKSVFELTQQHHHDHLICLDCGKVIEF
                     SDDSIEARQREIAAKHGIRLTNHSLYLYGHCAEGDCREDEHAHEGK"
     gene            complement(10907..11233)
                     /locus_tag="IRB70_004208"
     CDS             complement(10907..11233)
                     /locus_tag="IRB70_004208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634051.1"
                     /translation="MKKLILIAIMASGLVACAQSTAPQEDSRLKEAYSACINTAQGSP
                     EKIEACQSVLNVLKKEKQHQQFADQESVRVLDYQQCLRATQTGNDQAVKADCDKVWQE
                     IRSNNK"
     gene            complement(11283..12689)
                     /gene="chiP"
                     /locus_tag="IRB70_004209"
     CDS             complement(11283..12689)
                     /gene="chiP"
                     /locus_tag="IRB70_004209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chitoporin"
                     /protein_id="HBC0634052.1"
                     /translation="MRAFSGKRSTLALAIAGVTAMSGFVAMPEARAEGFFEDSTLTGG
                     IYYWQRERDRKDVTDGDKYKTNLSHSTWNANLDFQSGYAADMFGLDIAAFTAIEMAEN
                     GDSSHPNEIAFSKSNKAYDEDWSGDKSGISLYKAAAKFKYGPVWARAGYIQPTGQTLL
                     APHWSFMPGTYQGAEAGANFDYGDAGALSFSYMWTNEYKAPWHLEMDEFYQNDKTTKV
                     DYLHSIGAKYDFKNNFVLEAAFGQAEGYIDQYFAKASYKFDIAGSPLTTSYQFYGTRD
                     KVDDRSVNDLYDGTAWLQALTFGYRAADVVDLRLEGTWVKADGQQGYFLQRMTPTYAS
                     SNGRLDIWWDNRSDFNANGEKAVFFGAMYDLKNWNLPGFAIGASYVYAWDAKPATWQS
                     NPDAYYDKNRTIEESAYSLDAVYTIQDGRAKGTMFKLHFTEYDNHSDIPSWGGGYGNI
                     FQDERDVKFMVIAPFTIF"
BASE COUNT         3230 a         3168 c         3160 g         3389 t
ORIGIN      
        1 ttttattaat taaagccgta ataataaata cggcttttta tcttaaacaa cacacaaaaa
       61 taacaattca atattttata ttactgagta aaaagctcat cattaaataa attaagattg
      121 atcatttttt attgatcacc ttcacagttc aaccgtattt cctggataga ataccttcac
      181 cttcattcac atcaggaaag gtaaattaaa tggaaaataa cagccgcact atgccccata
      241 taaggcggac aactcatatt atgaagtttg ctcatcgcaa tagcttcgac tttcacttct
      301 tcaatgcccg ttagtctacc gactaagggc acttcagcgt acaggtcttc ctgactctct
      361 gtattacagg catatgcctg tattccgcag tgctcattct ctgttaaccc ttgtattatc
      421 agccaccgga ctgataaggg tttctgcatt ctgaaaaaag caaacttctg attaatttat
      481 cagcggggta actttgcttt ttttccggca cgatcgattt ctcattcgag aaattgagga
      541 cctgctatta ccaaaaataa agagttggaa aatgtcaaaa ttaaaaattg cggttagtga
      601 ttcttgcccg gactgtttta ccacgcagcg agaatgtatc tatattaatg aaaacagtaa
      661 tatcgatgtg gcggcaatag ttttatcgct caacgatgtt acacgcggaa aactcgatga
      721 aatcgatgcc acgggttatg gcatcccggt atttattgct actgaaaatc aagaacgtgt
      781 acccgcagag tatttgcccc gtatttcggg tgtctttgag aattgcgaat cgcgacgaga
      841 attttatggt cgtcagttag aaaccgcagc cagccattat gaaactcaac tgcgcccgcc
      901 cttcttccgc gcactggtcg attatgtcaa tcagggtaac agcgcgtttg attgccccgg
      961 tcatcagggc ggcgaatttt tccgtcgcca tccggcgggg aatcagtttg tggaatactt
     1021 tggtgaggcg ctgttccgtg ctgacttgtg caacgcggat gtggcaatgg gcgatctgct
     1081 gattcacgaa ggcgcgccat gcattgcaca gcaacatgcg gcaaaagtgt ttaatgccga
     1141 taaaacatac ttcgttctaa atggcacttc atcttctaac aaagtggttt taaacgccct
     1201 gttaacaccg ggggatctgg tgctgtttga ccgtaataac cataaatcta atcaccacgg
     1261 agcgttgcta caggctggcg caacaccagt ttatctggaa accgcacgca acccgtatgg
     1321 ctttatcggt ggtattgatg cccactgctt cgaagaaaat tacctgcgcg aactgattac
     1381 agaagtcgca ccgcagcggg caaaagaggc gcgtcctttc cgcctcgccg ttattcagct
     1441 aggcacttac gacggtacga tttataacgc ccgtcaggtg gtggataaaa tgggtcatct
     1501 gtgtgactac atcctctttg actccgcatg ggtcggctat gagcagttta tcccgatgat
     1561 ggcggactgt tcaccgctgt tactggatct aaatgagaac gatccgggta ttctggttac
     1621 gcaatctgtg cataaacagc aggctggttt ttcccagact tcacaaatcc ataaaaaaga
     1681 cagccatatc aaagggcaac agcgttatgt accgcacaaa cgcatgaaca acgcctttat
     1741 gatgcatgcc tccaccagcc cgttctatcc gctgtttgcc gcactggata tcaacgccaa
     1801 aatgcatgaa ggtgtcagcg gtcgtaatat gtggatggat tgtgtggtaa atggcattaa
     1861 tgcccgcaaa ctgatcctcg ataactgtca gcatattcgt ccattcgtac ctgaactggt
     1921 ggatggtaaa ccctggcagt cgtatgaaac agcgcaaatt gcggttgatc tgcgcttctt
     1981 ccagtttgta ccaggtgagc actggcattc ttttgaaggc tatgcagaga atcaatactt
     2041 tgtcgatccg tgcaaactgt tgctgacaac cccaggtatt gatgcacgta acggcgaata
     2101 tgaagcgttc ggtgtacccg cgacgattct tgctaacttc ctgcgcgaaa atggcgtagt
     2161 gccggaaaaa tgcgatctta actccatcct ctttctgctg actccggcag aagatatggc
     2221 caaacttcag caacttgctg ctctgctggt acgcttcgaa aaactgcttg agtccgacgc
     2281 gccattatca gaagtactgc cttccatcta caaacagcat gaagagcgct acaccggtta
     2341 taccctgcgt cagttgtgtc aggaaatgca tgatttgtat gcccgtcaca acgtgaaaca
     2401 actgcaaaaa gagatgtttc gtaaggaaca cttcccacgt gtcagcatga atccacaaga
     2461 agccaactac gcctatttac gcggtgaagt ggagctggtt cgtctgccgg atgcagaagg
     2521 ccgtatcgct gcagaaggtg cgcttcctta tcctccggga gtgctgtgtg ttgttccggg
     2581 tgaaatctgg ggtggtgctg ttctgcgtta cttcagcgct ctggaagaag ggatcaacct
     2641 gctgccaggt tttgcaccgg agcttcaggg tgtctatatc gaagaacatg atggtcgtaa
     2701 gcaagtttgg tgctatgtca tcaagcctcg tggtgcgcaa agcaccctgc tgaaagggga
     2761 aaaattatga gtcaggctaa atcgaacaag atgggcgtcg ttcagttaac catactgacg
     2821 atggtcaaca tgatgggctc cggtatcatc atgctgccga caaagcttgc cgaagttggg
     2881 acaatctcaa ttatctcctg gctggtgaca gccgtaggct caatggcgct ggcatgggca
     2941 ttcgcaaaat gcggcatgtt cagccgtaaa tcaggcggta tgggcggtta tgcggagtat
     3001 gctttcggta aatcagggaa ctttatggcg aactacacct acggtgtctc gctgctgatt
     3061 gctaacgtcg cgattgctat ttcggcggtt ggttacggca ccgaactgct cggcgcgagt
     3121 ttgtcgccag tgcagattgg tcttgcgacc atcggagtgc tgtggatttg taccgtggct
     3181 aactttggtg gtgcgcgcat taccgggcaa atcagtagca ttactgtgtg gggggtcatt
     3241 attccggtcg tcggtctgtg cattatcggc tggttctggt ttagcccgac gctgtacgct
     3301 aactcatgga accctcatca tgtaccgttc tttagcgctg taggttcctc catcgccatg
     3361 acattgtggg ctttcctcgg tctggagtct gcctgtgcca acgccgaagt agttgaaaac
     3421 ccggaacgta acgtgccgat tgcagttctt ggcggtacgt taggtgcggc ggtgatttat
     3481 atcgtctcca ccaacgtgat tgccgggatt gtgccaaata tggagctggc aaattcaacg
     3541 gcaccatttg gcctggcctt cgcacagatg ttcacgccgg gagtgggtaa agtcattatg
     3601 gcgctgatgg tgatgtcctg ctgcggttcg ctgcttggct ggcagttcac cattgcccag
     3661 gtgtttaaat cttctgccga tgaagggtac ttcccgaaaa ttttctcccg tgtgagcaaa
     3721 gtcgatgcac cagtacaggg aatgctgacc attgtcatca tccagagcgg attatcactg
     3781 atgaccatta gcccgtcgct gaacagtcag ttcaacgtgc tggttaacct ggccgttgtg
     3841 accaatatca tcccgtatat tctgtcgatg gcggcgttag tcattattca gcaggtcgcc
     3901 aatgtgccac catcaaaagc gaaagtagca aactttgttg cctttgttgg tgcgatgtac
     3961 agtttctatg cgctgtactc atccggggaa gaagccatgc tgtacggttc catcgtgacc
     4021 ttccttggtt ggacactgta tggtctggta tctccacgct ttgaactgaa aaataaacac
     4081 ggttaaaaaa agcgaaataa aaaagggcga ttgaatgatc gccctttctg tttgttgaca
     4141 aagagttcgt tatttatgcc gcatccggca ggtgtagggt ccaaacgcgg tcgaacacag
     4201 caactatttg cgtaattata tgaggcattt gcgacaaaaa ctggaacagg atctcgtccg
     4261 ccccgccatt tcattactga agccggtatt gggtatcggt ttatgctttg aaaaaagtgg
     4321 caatgtatgg ataaagtcat tttttattca aatataagga acttaatatt taaaaaatgt
     4381 cccatacaat gcctcatcat aaatgacacc gtagcacaca aggagcaagt agcgatgcgt
     4441 gaagtgagtc agttagtaaa tactgaagat tcagcctggc caataatcca gaattggtta
     4501 aaagaagcca caaaccatgc cgaactctta ccggttaata aagatttagc cgaaaccgca
     4561 ctttatcaat tacaggttac aacaaaatca ccgatgggtg cgcttgtcta tggctccgga
     4621 ggtctgctga ttgataacgg ttggttacgc atagcaggct ctggtcaccc ccggttacca
     4681 cgagatccag caagttggac acaacgccct gaattcgcaa gcgtgcgggc tttacccatc
     4741 gccgatgatg tcgcaggggg aatttttgct cttaatggtg gcgatcttgg ggaagatact
     4801 ggctgcgttt attattttgc gccagatacg ctgaattggg aaagtctgga ggttggatat
     4861 tctgagtttc ttcagtgggc attatccggt gatttagata ccttctatga aaatgtacgc
     4921 tggccgcaat ggcaagaaga cgtaataaaa ttatcggcaa cggaagcctt cactttctac
     4981 cctttcttat gggtacaatg tgaagaagca agaacaagaa aagttatttc gcttactgaa
     5041 ctctgggaaa tgcagtatca aatgaaagaa acaatcacgc aataagacat gttcaggtcc
     5101 gggtttcatt cccggactcg ctattttaat gtgtgtttat cgctttcaat tcttgctggc
     5161 aattttctga ctgacagcgt cgcaactcaa taatcccgac atgcatcatc gagccaaaaa
     5221 atccgctttc gctgacataa tcctcattaa ctatcggtcg agtgccgggc ttaccctggc
     5281 aaatccccat aaaaaatgag gtgtagcatt gccattcagg atttaaaccg gtcttttctt
     5341 gtgctgacat atcatgaaga taagtaagtt ctttttcgtt cccgcctgac aactgccagc
     5401 ggcgggtatt atcaggtaag ttatcgccac ggcaatttgt cttacaccgg gaaggcgcaa
     5461 tatttaccgc aatgctcccc gttaatcctc tggttttatc tttaggggtc agtaaccagt
     5521 caccagctaa tgatgattgt tcaggttggg cgcatgctgt cagcagtagt gtggcggtaa
     5581 ttaatgccac tctgacgacc agactccttt tggtcttcat tttgaattcc cttgagctat
     5641 tcagtttgtt ggcaaagtgc tcgttgttca tgccggatgc ggcgtgaacg ccttatccgg
     5701 cctacaaaat cgcgtaaatt caatatattg caccatcttc ccaagcctga taagcgtagc
     5761 gcatcaggca gtcataagta aaaaagggcg atcttctgac cgcccttttt cttattaaat
     5821 gtgtttacgc gtttttcaga acttcgctaa caatctcaac cgcttctttc tcaatctgct
     5881 tgcgatgttc ttccccgagg aagctttcgc agtagatttt gtatgcgtct tctgtgcctg
     5941 acggacgcgc ggcgaaccag ccgttgtcag tcatcacttt cagaccgcca atagaagcac
     6001 cgttgcccgg agcagcagtc aggcgcgcgg tgatcgggtc acctgccagg gtgctggcgc
     6061 tcaccatttc cggagacagc ttagacagcg ccgctttttg tgcggaagtc gcagctgcct
     6121 gcaaacggtt gtagctcggc gcaccaaagc gttttgccag ttcgttgtag tgttcctgcg
     6181 ggttcttacc ggtgacagcg gtgatttccg ccgccagcag acacataatg atgccgtctt
     6241 tgtcggtgga ccacggcgtg ccgtcgaaac gcaggaagga agcccctgcg ctctcttcgc
     6301 cgccaaagcc gaagctgccg tcgaacaggc catcaacaaa ccatttgaag cctaccggca
     6361 cttccaccag cctgcggccc aaatcattga ccacacggtc gatcatcgca gaagaaacca
     6421 gcgttttacc aacggcaaca tctttgcccc actgcggacg atgctggaac aggtaattga
     6481 tcgccaccgc caggtagtgg ttcggattca tcaaacctgc cggagtgacg ataccgtgac
     6541 ggtcataatc cgggtcgtta gcaaacgcca gatcgaactt atcacgcagt gccagcagac
     6601 ccgccatcgc acactcggag gagcagtcca tacggatcgc gccgtcttta tcgaggtgca
     6661 taaagcggaa ggtttgatcg acctgatcgt taacgatggt caggttaagg ttgtaatact
     6721 cgccaatacg cttccagtat tcgataccgg aaccgcccag cggatcaacg cccagcgtca
     6781 ggcccgcttt ctgaatcgcc gccatatcaa cgatatcggc cagaccttcc acaaacggct
     6841 gcaccagatc ctgctctttc acatgaccgg atgccatcgc ttcgtcgagg gagatacgct
     6901 tcacaccttt caggccatcg gccatcagtg cgttggccct gtcttccacc actttagtga
     6961 cgttggtatc agccgggccg ccatttggcg ggttgtactt gataccacca tcttccggcg
     7021 ggttatggga cggtgtaatc acgataccgt ctgccagcgg gccacctttt ttattgtgaa
     7081 ccaggatggc attggaaacg gcaggcgttg gagtgaagcc attgttttcc tgcacaataa
     7141 catcaacgcc gttcgctgcc agcacttcca gaacggaaat gaacgcaggc tcggacaggg
     7201 cgtgagtatc tttacccaca tagcaagggc cagtgatgcc gtttttcgca cgttcttcag
     7261 caattgcctg agcgatcgcc agaatgtgcg gctcgttaaa gctgtggcgc gctgcactgc
     7321 cacggtgacc ggaagtaccg aatttcaccg cgtgctccgc attccctgct tctggtttca
     7381 gtacataata ttgcgccgtc agttgggcga cgttaatcaa atcactctgt tgtgcaggtt
     7441 ggcctgcacg attgtggatt gccattgctt tgtcctttgt ctgcaacgtt ttagatagtt
     7501 ccgcaaacct tctcaatcaa ttccgccggg aattgcatcg actgcatgat gtgttcgatc
     7561 atgctgcatt tacggccggt gttggtgttg gtgatcaccc aatacggcgt accaggcaca
     7621 tgtttcggct tggtctgatt accatttttc agcagcgttt gttcatctgc cgcaaagtaa
     7681 acgcgtgtac gaccgtgcaa cgattccgtt gcttcggcaa acgcctgggc gtcaagagaa
     7741 tatagtgtag acaacagcag cataaagcga ttgaccgctc gcttttgctc tgcgtattca
     7801 tccgaaagca gaagttcacg cattgcgcga accttgtctt taatcgtttt gaccggcttc
     7861 gcttcgacga tagcaggtga cgcaacgcga acctctttcg tcaccggagc agcaggctgt
     7921 gatgcggcgg aaaatttcaa catacgccgt aaaatgtcgg atgcgctctc gccgatatgc
     7981 ttagtgtggc tggcaatata gctgtagagt tcatcatcaa cttcaatcgt tttcatctta
     8041 atccagtgca gtgtcttagc tgaatacaag tcgccaggag tatatgaata aatcccggca
     8101 gcggatagcg tcaagcctgg cttgcagaaa aactcggaat aaaccttatt tgttgcagcc
     8161 ctgtggcaca atggtcaaca taatacccta acccgacaac gcgaaaaaaa gaactttgcc
     8221 atgaaattga atatccgcgc gcaaactgca caaaaccagc acaataattc tcccatcgtt
     8281 cttgtccatg gtctgtttgg cagcctcgac aaccttggcg tactggctcg cgatctggta
     8341 aacgatcaca atatcatcca ggttgatatg cgtaaccacg gtctttcacc gagagatccg
     8401 gtaatgaatt acccggcgat ggcgcaggat cttgttgata ccctggatgc acagcagatc
     8461 gacaaagcaa catttatcgg tcactcaatg ggcggtaaag cggtaatggc tcttactgca
     8521 ctagcccccg atcgcattga caagctggtg gcgattgata ttgcgccggt cgactatcac
     8581 gtacgccgtc atgatgagat tttcgcggcc atcaacgcag tcagtgaatc agacgcacaa
     8641 acacgccagc aagcagcggc aataatgcgc cagcatctta atgaagaagg ggtgattcag
     8701 tttctgttga aatcttttgt tgacggggag tggcgcttta acgtgccagt attgtgggat
     8761 cagtatccgc atattgtggg ttgggagaaa atcccggcat gggatcatcc taccctgttt
     8821 atccctggcg gcaattctcc gtatgttagc gagcagtacc gtgatgattt actggcacaa
     8881 tttccacagg ctcgggcgca tgtgattgca ggcgcgggtc actgggtcca tgctgaaaaa
     8941 ccggatgcgg tattacgcgc tatccgtcgc tatctcaatg attaacgcaa ctgattaaaa
     9001 acccagcgtc cgcgtcgctt tccgcgcgtg gacgttggcg tgactcctca cgctgatgta
     9061 ttatggcgcg ctatccatcc gggcagaggc ctggctgatt gtttcccccg aagtcaccaa
     9121 gatcatggcc aaagaacaaa cggaccgtac gacattagat ctgttcgcgc acgagcgtcg
     9181 accgggacga ccgaaaacta atccgctttc gcgcgatgaa cagctgcgta ttaataaacg
     9241 taaccaacta aaacgcgaca aagtacgtgg ccttaagcgt gtcgaactga agctgaacgc
     9301 ggaagctgtc gaggcactga acgagctggc ggagtcgcgc aatatgagcc gtagcgaact
     9361 gatcgaagag atgttaatgc agcaactggc ggcgctgcgt agtcagggca tcgtttaaat
     9421 ttccactttc atgtagcaca gtgtgcagtc ctgctcgttt gctgattccg caagactgcc
     9481 tgttctgcta tgattgcctt tatccgtggg caattttcca cccccatttc aataagtttc
     9541 aagaggttat ttcactcatg gctatcactg gcatcttttt cggcagcgac accggtaata
     9601 ccgaaaatat cgcaaaaatg attcaaaaac agcttggtaa agacgttgcc gatgtccatg
     9661 acattgcaaa aagcagcaaa gaagatctgg aagcttatga cattctgctg ctgggcatcc
     9721 caacctggta ttacggcgaa gcgcagtgtg actgggatga cttcttcccg actctcgaag
     9781 agattgattt taatggtaaa ctggttgcgc tgtttggttg tggcgaccag gaagattacg
     9841 cagaatactt ctgcgatgca ttgggcacca tccgcgacat cattgaaccg cgcggcgcaa
     9901 ctatcgttgg tcactggcca actgcgggct accacttcga agcgtcaaaa ggtctggctg
     9961 atgatgacca ctttgtcggt ctggctatcg acgaagatcg tcagccggaa ctgaccgctg
    10021 aacgtgtaga aaaatgggtt aaacaaattt ctgaagagct gcatctcgac gaaattctca
    10081 atgcctgatg tgatgcggcg tagactcatg tctacgccgt attaatagat aatgccaatc
    10141 aaaataattg ctacaaattt gtaacttttg ctgttgtacc tgtacaatgt cccggtgttc
    10201 aagtggcctt gccgttgtaa atgtaagctg tgccacgttt ttattaacaa tatttgccag
    10261 ggacttgtgg ttttcattta ggcgtggcaa ttctataatg atacgcatta tctcaagagc
    10321 aaattctgtc acttcttcta atgaagtgaa ccgcttagta acaggacaga ttccgcatga
    10381 ctgataacaa taccgcccta aagaaagctg gcctgaaagt aacgcttcct cgtttaaaaa
    10441 tcctggaagt tcttcaggag ccggacaacc atcacgtcag tgcggaagat ttatacaaac
    10501 gtctgatcga tatgggtgaa gaaattggtc tggctacggt atatcgcgta ctgaaccagt
    10561 ttgacgacgc tggtatcgtc acccgccaca attttgaagg cggtaaatcc gtatttgaac
    10621 tgacacagca acatcaccac gatcacctga tctgcctcga ctgcggcaag gtaatcgaat
    10681 ttagtgatga ttccatcgaa gcgcgtcagc gtgaaattgc cgcaaaacat ggcattcgcc
    10741 tgactaacca cagtctctat ctttacggtc actgtgccga aggcgattgc cgcgaagatg
    10801 agcacgcgca cgaaggcaaa taagccagcc tgaacgagaa aagccaacct gcgggttggc
    10861 ttttttatgc aagggaaata agaaaagcga gagttacagc tctcacttat ttgttattac
    10921 tgcgaatttc ctgccagacc ttatcacaat cggctttcac cgcctgatca tttccggttt
    10981 gcgttgcgcg cagacactgc tgataatcca gtacgcggac actttcctgg tcggcaaact
    11041 gctgatgttg tttctctttc ttcagcacgt ttaacacgct ctggcaggct tcaatttttt
    11101 ctggcgaacc ttgtgcggtg ttgatacagg cgctgtatgc ctctttcaga cgactgtctt
    11161 cctgtggcgc ggttgattgc gcacaagcta ccagccccga tgccattatg gcgatgagaa
    11221 tcagtttttt catagcaaat tcctcaaacg tgcggcaggc acaaaacctg ccgcgtcggg
    11281 catcagaaga tggtgaatgg tgcgattacc ataaatttca cgtcacgctc atcctggaag
    11341 atgttgccgt aaccaccgcc ccagcttggg atgtcggagt ggttgtcgta ttcggtgaag
    11401 tgcagtttga acatcgtgcc tttggcgcga ccgtcctgaa tggtgtagac cgcatccagg
    11461 ctgtaggcag actcttcaat agtccggttt ttgtcgtagt acgcatccgg attgctctgc
    11521 caggtagcgg gtttagcatc ccatgcgtaa acgtaggaag cgccgatggc gaagcctgga
    11581 agattccagt ttttcaggtc atacatcgca ccgaagaaga ccgctttttc gccgttagcg
    11641 ttgaagtcgg aacggttatc ccaccagata tccaggcggc cgttggagga agcgtaggtt
    11701 ggagtcatac gttgcaggaa gtatccctgc tgaccgtcag ccttaaccca ggtaccttcg
    11761 aggcgcaaat ccactacgtc agccgcccgg taaccaaagg tcaacgcctg cagccaggcg
    11821 gtgccgtcat aaagatcgtt gacgctgcga tcgtcaactt tatcgcgcgt accgtagaac
    11881 tggtagctgg tggttaacgg gctaccggcg atatcaaatt tgtagctggc tttggcaaag
    11941 tattgatcga tatacccttc cgcctgacca aacgctgctt ccagtacaaa gttatttttg
    12001 aagtcgtact tcgcaccgat ggagtgcaga taatcaactt tggtggtttt atcgttctga
    12061 taaaactcat ccatttccag atgccacggt gctttgtatt cgttggtcca catgtaggag
    12121 aaactcaacg caccagcatc gccgtaatca aaattcgccc cggcctccgc cccctgataa
    12181 gtacccggca taaagctcca gtgtggcgct aacagcgtct gaccggttgg ctgaatataa
    12241 cctgccctcg cccataccgg accgtattta aatttggccg ctgctttata caggcttata
    12301 ccgcttttat cgccggacca gtcttcgtca taggctttat tactttttga aaacgcgatt
    12361 tcgttcgggt gagagctgtc gccgttttct gccatttcaa tcgctgtaaa cgcggcaata
    12421 tccagaccga acatatcagc ggcatagcca gactgaaaat cgagattagc gttccaggtg
    12481 gagtgagaaa ggttggtttt atatttgtcg ccgtcggtaa catctttacg gtcacgttca
    12541 cgctgccagt aatagatacc gccggttaag gttgaatctt cgaagaatcc ttcggcgcga
    12601 gcctctggca ttgccacaaa gcccgacatt gctgtaacac cggcgatagc cagcgccagc
    12661 gtactacgtt tgccactaaa cgcacgcatg ggttaatcct ctttgacgta taaattgctg
    12721 caccaaaggt gaacagcgaa aaaaataaaa attaaaaaag tagcgttgag aaaagtctcg
    12781 ctgactacag gaacagacta tttttcgcga cgcgaattat caatctcttt ctgtaaccag
    12841 aatgtaagaa catgagcaac cgcacatatt ttgatgattt ttgttacaag gcttaagttg
    12901 tagttgaaag gtgtgttgaa gaaaaaatgc gtgaatttcc agcaaga
//
LOCUS       DADXDL010000117        12576 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.117, whole genome shotgun sequence.
ACCESSION   DADXDL010000117 DADXDL010000000
VERSION     DADXDL010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12576
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.117"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            260..1153
                     /locus_tag="IRB70_004210"
     CDS             260..1153
                     /locus_tag="IRB70_004210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016234625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0634053.1"
                     /translation="MLKENFNELQIFLVVARERSFTKAAGKLGVSQSALSHAMKALEE
                     RLNIRLLTRTTRSVAPTEAGERIIACLEPRIDELEQELESLIQLNSTPSGNIRLSAGE
                     HAARSLVWPKLKPFLREYPEINVELVVDNGFVDIVEGRFDAGIRLGENVDKDMVAVRI
                     GPDMRMAVVGAPAYFAANPAPETPHELQNHRCINMRLPTAGGLYHWEFEREGKPLRVK
                     VDGQLTCSPLPERIDAALSGFGIACVPEDMVQEYIKSGKLIQVLQEWCPTFPGYYLYY
                     PSRKQHPPAFALLIDALRYTE"
     gene            complement(1184..2173)
                     /locus_tag="IRB70_004211"
     CDS             complement(1184..2173)
                     /locus_tag="IRB70_004211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001172283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBC0634054.1"
                     /translation="MQKRYLGKSGLEVSALGLGCMGLSHGYGPATDTRQAIELIRAAV
                     ERGVTFFDTAEVYGPYLNEEVVGEALKPFRDRVVIATKFGFTFGDDNKQQILNSRPEH
                     IREAVEGSLRRLKTDVIDLLYQHRVDPDVPIEDVAGTVKDLIAEGKVKHFGLSEAGAQ
                     TIRRAHAVQPVTALQSEYSMWWREPEQEILPLLEELGIGFVPFSPLGKGFLTGAIKPG
                     TTFGKDDYRSTVPRFAAQAIEANEKLVTLLGELAAEKGVTSAQIALAWLLAQKPWIVP
                     IPGTTKLNRLEENLAAADIVLSQKDTQQITEALETIKIVGERYSPEHQARVGR"
     gene            complement(2200..3051)
                     /locus_tag="IRB70_004212"
     CDS             complement(2200..3051)
                     /locus_tag="IRB70_004212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001195265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBC0634055.1"
                     /translation="MQKVKLNNGIEMPLLGFGVFQMTDAAECERAVIDAINSGYRLID
                     TAASYQNEIQVGNALKQSGIARNELFVTTKLWLQDTSYEGAKAQFERSLNRLQLDYVD
                     LYLIHQPYGDVHGAWRAMEELQQAGKIRAIGVSNFHPDRLADLIAFNNVVPAVNQVEV
                     NPFNQQLQAVPWMQSRGIQPEAWAPFAEGKNGLFQHPVLTAIGEKYGKSVGQVVLRWI
                     YQRGIVSLAKSVRKERMEENINILDFELSPEDMLQITALDTATSAFFSHRDPAMVEWL
                     TGRKLDV"
     gene            3617..7870
                     /gene="fdeC"
                     /locus_tag="IRB70_004213"
     CDS             3617..7870
                     /gene="fdeC"
                     /locus_tag="IRB70_004213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000092554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="intimin-like adhesin FdeC"
                     /protein_id="HBC0634056.1"
                     /translation="MSRYKTDNKQPRFRYSVLARCVAWANISVQVLFPLAVTFTPVMA
                     ARAQHAVQPRLSMGNTTVTADNNVEKNVASFAANAGTFLSSQPDSDATRNFITGMATA
                     KANQEIQEWLGKYGTARVKLNVDKDFSLKDSSLEMLYPIYDTPTNMLFTQGAIHRTDD
                     RTQSNIGFGWRHFSGNDWMAGVNTFIDHDLSRSHTRIGVGAEYWRDYLKLSANGYIRA
                     SGWKKSPDVEDYQERPANGWDIRAEGYLPAWPQLGASLMYEQYYGDEVGLFGKDKRQK
                     DPHAITAEVNYTPVPLLTLSAGHKQCKSGENDTRFGLEVNYRIGEPLEKQLDTDSIRE
                     RRMLAGSRYDLVERNNNIVLEYRKSEVIRIALPERIEGKGGQTLSLGLVVSKATHGLK
                     NVQWEAPSLLAEGGKITGQGSQWQVTLPAYRPGKDNYYAISAVAYDNKGNASKRVQTE
                     VVITGAGMSADRTALTLDGQSRIQMLANGNEQKPLVLSLRDAEGQPVTGMKEQIKTEL
                     TFKPAGNIVTRSLKATKSQAKPTLGEFTETEAGVYQSVFTTGTQSGEATITVSVDGMS
                     KTVTAELRATMMDVANSTLSANEPSGDVVADGQQAYTLTLTAVDSEGNPVTGEASRLR
                     LVPQDTNGVTVGAISEIKPGVYSATVSSTRAGNVVVRAFSEQYQLGTLQQTLKFVAGP
                     LDAAHSSITLNPDKPVVGGTVTAIWTAKDAYDNPVTSLTPEAPSLAGAAAVGSTASGW
                     TNNGDGTWTAQITLGSTAGELDVMPKLNGQDAAANAAKVTVVADALSSNQSKVSVAED
                     HVKAGESTTVTLIAKDAHGNAISGLSLSASLTGAASEGATVSNWTEQGDGSYVATLTT
                     GGKTGELLVMPLFNGQPAATDAARLTVVAGEMSSANSTLVADNESPTVKTTTKLTFTV
                     KDAYGNLVTGLKPDAPQFSGAASTGTERPSAGSWTETSNGVYVATLTLGSAAGQLSVM
                     PRVNGQNAVAQPLVLNVAGDASKAEIRDMTVKVDNQLANGQSTNQVTLTVVDSYGNPL
                     QGQEVTLTLPQGVTSKTGNTVTTNAAGKADIELISTVAGKLEIAAAVKNSQKTVTVKF
                     NADASTGQANLQVDTAVQKVANGKDAFTLTATVEDKNGNPVPGTLVTFNLPRGVKPLT
                     GDNVWVKANDEGKAELQVVSVTAGTYEITASAGNDQPSDAQTITFVADKATATVSGIE
                     VIGNYALADGKAKQTYKVTVTDANNNLLKDSEVTLTASPASLNLEPNGTATTNEQGQA
                     IFTATTTVAATYTLTAQVSQNNGQVSTKTAEAKFVADDKNAVLAASSDVTSLVADGVQ
                     TATMTVTLFSANNPVGGNVWVDIEAPEGVTEKDYQFLPSKNDHFVSGKITRTFSTSKP
                     GVYTFTFNALTYGGYEMKPVTVTITAVDADTAKGEEAMK"
     gene            complement(7991..8848)
                     /locus_tag="IRB70_004214"
     CDS             complement(7991..8848)
                     /locus_tag="IRB70_004214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308364.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0634057.1"
                     /translation="MIRQKILQQLLEWIECNLEHPISIEDIAQKSGYSRRNIQLLFRN
                     FMHVPLGEYIRKRRLCRAAILVRLSAKSMLDIALSLHFDSQQSFSREFKKLFGCSPRE
                     YRHRDYWDLANIFPSFLIRQQQKTECRLVNFPETPIFGNSFKYDIEVSNKSPDEEVKL
                     RRHHLVRCMKNFKTDIYFVSTFEPSTKSVDLLTVETFAGTVCKQTDSEMPKEWIINRG
                     LYASFRYEGEWEHYPEWARNLYLMELPARGLARVNGSDIERFYYNEDFVEKDSNDVVC
                     EIFIPVRPV"
     gene            9096..9965
                     /locus_tag="IRB70_004215"
     CDS             9096..9965
                     /locus_tag="IRB70_004215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308365.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBC0634058.1"
                     /translation="MEFSVLSNNLKMPMMGFGVFQVTDKDVCKQSVLNAIRTGYRLID
                     TAAVYGNEDAVGEAVREAISEGLCTREELFITSKLWVQDMLNQDIAAAGIEASLKKSG
                     LEYFDLYLLHQAMRDYFSAWRALEDAYEEGKLKAIGVSNFYPHVLANFCETVRVKPMV
                     NQVELHPYFAQPEALATMKYYNVQPEAWAPLGGGRHNPFENNLLQSIADAHQKSISQV
                     ILRWNIQRGVVVIPKSTHQQRIEENFAIWDFSLTEKEMAQISSLDLGYVGESVKHFNP
                     EFVRGCLAVKIHD"
     gene            complement(10125..10718)
                     /gene="rclC"
                     /locus_tag="IRB70_004216"
     CDS             complement(10125..10718)
                     /gene="rclC"
                     /locus_tag="IRB70_004216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414835.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="reactive chlorine species resistance protein
                     RclC"
                     /protein_id="HBC0634059.1"
                     /translation="MEKYLHLLSRGDKIGLTLIRLSIAIVFMWIGLLKFVPYEADSIT
                     PFVANSPLMSFFYEHPEDYKQYLTHEGEYKPEARAWQSANNTYGFSNGLGVVEVIIAL
                     LVLANPVNRWLGLLGGLMAFTTPLVTLSFLITTPEAWVPALGDAHHGFPYLSGAGRLV
                     LKDTLMLAGAVMIMADSARDILKQRSNESSSTLKTEY"
     gene            complement(10730..10966)
                     /locus_tag="IRB70_004217"
     CDS             complement(10730..10966)
                     /locus_tag="IRB70_004217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414837.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBC0634060.1"
                     /translation="MFKKPVLFATLLSGVMAFSTNADDKIILKHISVSSVSASPTVLE
                     DAIADMARKYNASSWKVTSMRIDNNSTATAVLYK"
     gene            complement(11075..12400)
                     /locus_tag="IRB70_004218"
     CDS             complement(11075..12400)
                     /locus_tag="IRB70_004218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414838.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridine nucleotide-disulfide oxidoreductase"
                     /protein_id="HBC0634061.1"
                     /translation="MNKYQAVIIGFGKAGKTLAVTLAKAGWRVALIEQSNAMYGGTCI
                     NIGCIPTKTLVHDAQQHTDFVRAIQRKNEVVNFLRNKNFHNLADMLNIDVIDGQAEFI
                     NNHSLRVHRPEGNLEIHGEKIFINTGAQTVVPPIPGITTTPGVYDSTGLLHLKELPGH
                     LGILGGGYIGVEFASMFANFGSKVTILEAASLFLPREDRDIADNIATILRDQGVDIIL
                     NAHVERISHHENQVQVHSEHAQLAVDALLIASGRQPATASLHPENAGIAVNERGAIVV
                     DKQLHTTADNIWAMGDVTGGLQFTYISLDDYRIVRDELLGEGRRSTDDRKNVPYSVFM
                     TPPLSRVGMTEEQARESGADIQVVTLPVAAIPRARVMNDTRGVLKAIVDNKTQCILGA
                     SLLCVDSHEMINIVKMVMDAGLPYSILRDQIFTHPSMSESLNDLFSLVK"
BASE COUNT         3380 a         2844 c         3090 g         3262 t
ORIGIN      
        1 tctaaagttc gtgcttttat tgattttatg gtggagaaaa gagtaaaaat agaaagttaa
       61 tgatgtgtgt cagaatatcg gtaagaagaa tggcgcaatc gtgaggatac gtttattcat
      121 aataaatctc ctgaaagttt agaattattt tcgatacagc cagattatca ttgttactaa
      181 taatgtggtt aaaataatag catctatgcc ccccttcatg agtgtctgtg aagaggatgc
      241 ttctacaagg aaatcgccaa tgctcaaaga aaacttcaac gaactgcaaa tctttcttgt
      301 ggtggcaaga gagcgaagtt ttaccaaagc agcgggcaaa ctcggagtct ctcagtctgc
      361 acttagccat gcaatgaagg ctttggagga aaggctcaat atccgcctcc tgacacggac
      421 tacccgcagt gtggctccca cagaagcggg ggagagaatc attgcctgcc ttgaaccgcg
      481 tattgacgag cttgaacagg aactggaatc acttattcaa ttgaacagca cgccctccgg
      541 gaatattcgg ttatctgccg gggaacatgc cgcgcgaagt ctggtctggc cgaagctaaa
      601 accttttctc agagagtatc ccgaaatcaa tgtcgaactg gtggtggata acggttttgt
      661 cgatattgtt gaaggccgtt ttgatgccgg gatacgactg ggtgaaaatg ttgataaaga
      721 tatggttgca gtcaggattg gacctgatat gcggatggct gtggtgggag ctccggcgta
      781 ttttgctgca aaccctgcgc ctgaaacgcc tcatgagcta caaaatcatc gctgtatcaa
      841 catgcgtttg ccaactgccg gtgggcttta ccactgggag ttcgagcgag aagggaaacc
      901 gcttcgcgtt aaggttgatg ggcaactgac gtgtagtcca ttgccagaaa gaattgatgc
      961 cgcgttatca gggtttggga tcgcttgtgt ccctgaagac atggttcagg agtatataaa
     1021 gtcaggcaag cttattcagg tgttacagga gtggtgtcca acttttcctg ggtattatct
     1081 ttactacccc agccgcaagc agcatccgcc agcttttgcg ctgttgatcg atgcgcttcg
     1141 ctacaccgaa taacgggtcc tttatcctgg acccgtttgg gtattagcgg cctacgcgtg
     1201 cctgatgttc aggcgagtaa cgttcaccga cgattttaat tgtttccagc gcctcggtta
     1261 tctgctgcgt atctttctgc gaaagaacaa tgtcagcagc ggccaggttt tcttccagcc
     1321 ggttcagttt agtggtgcca gggatgggaa caatccacgg cttttgtgct aatagccatg
     1381 ccagtgcgat ttgtgcagac gttacccctt tctccgcagc cagttcacct aacaaggtga
     1441 ccagtttttc attggcttca atggcttgtg ctgcgaaacg cggtacggtg ctgcggtaat
     1501 catctttgcc gaaagtggtt cccggcttaa tcgcccctgt caggaaacct ttacctagtg
     1561 ggctgaaggg gacaaaacca attcccagtt cctccagcaa cggcagaatt tcctgttcag
     1621 gctcacgcca ccacatggaa tattcgcttt gcagggcggt gacaggttgt accgcatgtg
     1681 cacgacgaat ggtttgtgct cctgcttcag acaggccgaa atgtttgacc ttaccttctg
     1741 cgatgaggtc tttcaccgtt cctgcaacat cttcaatagg aacatctgga tcaacacggt
     1801 gttgatacag caggtcaata acatctgttt tcagacgacg taatgatcct tcaacggctt
     1861 cacggatatg ttccggacgg ctgtttaaaa tctgctgctt attatcatcg ccgaaggtaa
     1921 aaccgaattt agtggcaatt accacgcggt cacgaaacgg ttttaaggct tcgccgacca
     1981 cttcttcatt cagatacgga ccatacactt cggcggtatc gaagaaggtg acgccacgtt
     2041 caaccgcagc acgaataagt tcgatagcct gacgggtatc ggtcgccggg ccgtagccgt
     2101 ggcttaagcc catgcaaccg agcccaaggg cggagacttc gagtccggat ttacccagat
     2161 aacgtttttg cattgaatga atacctcttt tatcgcggct taaacatcaa gtttgcggcc
     2221 agtcagccat tccaccattg cgggatcgcg gtgagagaag aatgcgctgg ttgcggtatc
     2281 cagggcggta atttgcagca tatcttcagg gctgagttca aaatcgagaa tgttgatgtt
     2341 ctcttccatg cgttcttttc gcactgattt tgccagtgaa acaatgcctc gttggtagat
     2401 ccagcgcaga acaacctggc ccacgctttt gccatacttc tcgccaattg ccgtgagaac
     2461 aggatgctgg aacagaccat ttttcccttc cgcaaacggt gcccaggctt ctggctgaat
     2521 gccacgactt tgcatccagg gaacggcctg tagctgctga ttgaaagggt taacttcaac
     2581 ctggtttacc gccggaacga cgttattaaa agcgataagg tctgccagtc ggtcaggatg
     2641 gaagttactg acgccaatag cgcgaatttt accggcctgt tgcagctctt ccatggcacg
     2701 ccaggctccg tggacatcgc catatggctg gtgaatcaag tacaggtcaa cgtaatcaag
     2761 ttgcagtcga ttcagagagc gttcgaactg ggctttggcc ccttcgtaac tggtatcctg
     2821 caaccagagt ttcgtggtga caaagagttc gttacgggcg ataccgcttt gtttcagtgc
     2881 gttcccgacc tggatttcat tttgataaga ggcggcggtg tcaatcagtc gataaccgct
     2941 gttaatagcg tcaatgaccg ctctttcgca ttcggcggca tcggtcatct gaaatacacc
     3001 aaagcccaac aggggcattt caataccgtt gttcagtttt actttttgca tggtgttatc
     3061 cttccgttat cgttcatgag aagcataacg taaagggaag agctcgatta gacggcagga
     3121 tttgtcaggg gttatgaaca aaattcataa atctgtttga gggttgagat tagtcgtgca
     3181 agttcgatat tcccgcaatt tacagtccga tgaaggaaaa tgaatatcca taaaaaatat
     3241 attggtttat cctggcgtat atacctactt cgacgtattt ccaatagttg ctaattaaag
     3301 gcaggtcatt attattcact ctgaataatg aattattcac tgtccgcaga gtaagaaata
     3361 taacttaggt atctatttaa tgacttgcac aaaaagctaa atttttaccc ataaataaaa
     3421 atataatccc gcgcccaccc acctgatgag tggctacaga cactggatat attaggtggc
     3481 ggtgtacttt cttacataaa ggtatttcct tttctgtgga aaaggaaacc gggaaatccc
     3541 tggtttttct gacaagcaga cgccattatt tgtgtctgcc tatgttcgtt aattcgttca
     3601 tcaggaaaat atctcaatgt cacgttataa aacagacaat aaacagccac gatttcgtta
     3661 ttcagttctg gcccgctgcg tggcgtgggc aaatatctct gttcaggttc tttttccact
     3721 cgctgtcacc tttaccccag taatggcggc acgtgcgcag catgcagttc agccacggtt
     3781 gagcatggga aatactacgg taactgctga taataacgtg gagaaaaatg tcgcgtcgtt
     3841 tgccgcaaat gccgggacat ttttaagcag tcagccagat agcgatgcga cacgtaactt
     3901 tattaccgga atggccaccg ctaaagctaa ccaggaaata caggagtggc tcgggaaata
     3961 cggtactgcg cgcgtcaaac tgaatgtcga taaagatttc tcgctgaagg attcttcgct
     4021 ggaaatgctt tatcctattt atgatacgcc gacaaatatg ttgttcactc agggggcaat
     4081 acatcgtaca gacgatcgta ctcagtcaaa tattggtttt ggctggcgtc atttttcagg
     4141 aaatgactgg atggcggggg tgaatacttt tatcgatcat gatttatccc gtagtcatac
     4201 ccgcattggt gttggtgcgg aatactggcg tgattatttg aaactgagcg ccaatggtta
     4261 tatccgggct tctggctgga aaaaatcacc ggatgttgag gattatcagg aacgcccggc
     4321 gaatggctgg gatattcgtg ctgagggcta tttacctgcc tggccgcagc ttggcgcaag
     4381 cctgatgtat gaacagtatt atggcgatga agtcgggctg tttggtaaag ataaacgcca
     4441 gaaagatcca catgcgatta ccgctgaagt gaattacacg ccagtgcctc ttctgaccct
     4501 gagtgccggg cataagcagt gcaagagtgg tgagaatgac actcgctttg gcctggaagt
     4561 taattatcgg attggcgaac ctctggaaaa acaactcgat acagacagca ttcgcgagcg
     4621 tcgaatgctg gcaggcagcc gctatgacct ggttgagcgt aataacaaca tcgttcttga
     4681 gtaccgcaaa tctgaagtga ttcgtattgc tctgcctgag cgtattgaag gcaagggcgg
     4741 tcagacactt tccctggggc ttgtggtcag caaagcaact cacggactga aaaatgtgca
     4801 atgggaagcg ccgtcattac tggctgaagg tggcaaaatt accggtcagg gtagtcagtg
     4861 gcaagtaacg ctcccggctt accgtccagg caaagacaat tattatgcga tttcagcagt
     4921 tgcctacgat aacaaaggta atgcctcgaa acgtgtgcag acagaagtgg ttattaccgg
     4981 agctggtatg agcgccgatc gcacggcgtt aacgcttgac ggtcagagcc gtattcaaat
     5041 gcttgctaac ggtaatgagc aaaagccgct ggtgctgtct ctgcgcgacg ccgagggcca
     5101 gccagtcacg ggcatgaagg agcagatcaa gactgaacta accttcaaac cggctggaaa
     5161 tattgtgact cgttccctga aggccactaa atcacaggca aagccaacac tgggtgagtt
     5221 caccgaaact gaagcagggg tgtatcagtc tgtctttacg accggaacgc agtcaggtga
     5281 ggcaacgatt actgttagcg ttgatggcat gagcaaaacc gtcactgcag aactgcgggc
     5341 cacgatgatg gatgtggcaa actccaccct gagcgctaac gagccgtcag gtgacgtggt
     5401 tgctgatggt cagcaagcct acacgctgac gctgactgcg gtggactccg agggtaatcc
     5461 ggtgacggga gaagccagcc gcctgcgact tgttccgcaa gacactaatg gtgttaccgt
     5521 tggtgccatt tcggaaataa aaccaggggt ttacagcgcc acggtttctt cgacccgtgc
     5581 cggaaacgtt gttgtgcgcg ccttcagcga gcagtatcag ctgggcacat tacaacaaac
     5641 gctgaagttt gttgcagggc cgcttgatgc agcacattcg tccatcacac tgaatcctga
     5701 taaaccggtg gttggcggta cagttacggc aatctggacg gcaaaagatg cctatgacaa
     5761 ccctgtgacc agcctcacgc cggaagcgcc gtcattagcg ggtgctgcgg ctgtaggttc
     5821 tacggcatct ggctggacaa ataatggtga tggaacatgg actgcgcaga ttactctcgg
     5881 ctctacggcg ggtgaattag acgttatgcc gaagctaaat ggacaggatg cggcagcaaa
     5941 tgcggcaaaa gtaaccgtgg tggctgatgc attatcttca aaccagtcga aagtctctgt
     6001 cgcagaagat cacgtaaaag ccggtgaaag cacaaccgtg acgcttattg caaaagatgc
     6061 gcatggcaac gctatcagtg gcctttccct gtcggcaagc ctgacgggtg ctgcgtctga
     6121 aggggcgacg gtatccaact ggaccgagca gggcgatggt tcctatgtcg ctacgctgac
     6181 cacaggggga aagacgggtg agcttctcgt tatgccgcta ttcaacggtc agccagcagc
     6241 caccgatgct gcgcggttga ctgtcgttgc gggggagatg tcatcagcga actctacgct
     6301 tgttgctgac aatgagtctc cgaccgtcaa aacgacgacg aaactcacct tcaccgtgaa
     6361 ggatgcgtac gggaaccttg tcaccgggct gaagccagat gcaccgcagt ttagtggtgc
     6421 cgccagcacg gggacagagc gaccttcagc aggaagctgg acagaaacaa gtaatggggt
     6481 ctacgtggcg accttaacgc tgggatcggc tgcaggtcag ctgtctgtga tgccgcgagt
     6541 gaacggccaa aatgccgttg ctcagccact ggtgctgaac gttgctggtg acgcatctaa
     6601 ggctgagatt cgtgatatga cggtgaaggt tgataaccag ctggcaaatg gacagtcgac
     6661 taaccaggta accctgaccg ttgtggacag ctatggtaac ccgttgcagg ggcaagaagt
     6721 tacgctgact ttaccgcagg gtgtgaccag caagacgggg aatacagtaa caaccaatgc
     6781 ggcaggtaaa gcggatattg agttgatatc aaccgttgca gggaaacttg aaatcgcggc
     6841 cgcggtgaaa aactctcaga agacggtcac ggtgaaattc aacgcggatg ccagcaccgg
     6901 tcaggcaaac ctgcaggtag acaccgccgt tcaaaaagtg gcaaacggca aagatgcctt
     6961 tacgctgacg gcgaccgttg aggataaaaa cggtaaccct gttccaggca ctctggtgac
     7021 ctttaatctg ccccggggtg tcaagccgct tacaggcgat aatgtctggg tgaaagccaa
     7081 cgatgagggg aaagcagagt tgcaggtggt ttccgtgact gccggaacct atgagatcac
     7141 ggcgtcggca ggaaatgacc agccttcgga tgcgcagact ataacgtttg tggccgataa
     7201 ggcgaccgca accgtctccg gtattgaggt gattggcaac tatgcgctgg cggatggcaa
     7261 agccaaacag acgtataaag ttacggtgac tgatgccaat aacaacctgt tgaaagatag
     7321 cgaggtgacg ctgaccgcca gcccggcttc gttaaacctg gaaccgaatg gcactgcgac
     7381 aacgaatgag caagggcagg ctattttcac cgccaccact actgttgcgg cgacatatac
     7441 actcacggcg caagtgagtc agaacaacgg tcaggtatca acgaaaaccg ccgaagctaa
     7501 attcgtcgcg gatgataaaa acgcggtgct cgctgcatca tctgatgtga cttctctggt
     7561 ggcggatggg gtacagaccg caacaatgac ggttaccctg ttctcggcaa ataaccctgt
     7621 tggggggaat gtgtgggtcg acattgaggc tccggaagga gtgacggaga aggattatca
     7681 attcctgccg tcgaaaaatg accatttcgt gagcggaaaa atcacgcgta catttagtac
     7741 cagcaagcct ggtgtctata cgttcacatt taacgccctg acctatggcg ggtacgaaat
     7801 gaagccagtg acggtgacca taaccgcggt ggatgccgat acggcaaagg gcgaggaggc
     7861 gatgaaataa tattaagagt atgaaagtaa cattctaata aacaataatg gcgttgacat
     7921 cttcaacgcc attatttatt gaattgcctg acagtagtct cgttataaat tcatttagat
     7981 atagcgataa ctaaaccgga cgaacaggga taaatatttc gcaaacaaca tcattgctat
     8041 ccttttctac gaaatcttca ttgtaataaa atcgctcaat atcactgccg ttcactctgg
     8101 ctaaccccct ggcaggtaat tccatcagat agaggtttcg cgcccattca gggtagtgct
     8161 cccactcacc ttcatagcgg aaagaggcat acagtcctcg gttaattatc cactcttttg
     8221 gcatctctga atcggtttgt ttacataccg taccggcaaa agtttcaact gtgagcaaat
     8281 cgactgattt tgttgacggt tcgaacgtgg agacgaaata gatatccgtc ttaaaattct
     8341 tcatacatct gactaaatga tgacgtcgca gtttgacttc ttcatccggt gacttattcg
     8401 acacttcaat atcatattta aatgaattgc caaaaatagg tgtctcagga aagttgacta
     8461 atctacactc cgtcttttgc tgttgacgta ttaaaaaaga agggaagata tttgcgagat
     8521 cccaataatc acggtggcgg tattcacggg gagagcagcc gaataacttt ttaaattcgc
     8581 ggctgaatga ctgctgtgaa tcaaaatgca aagagagtgc aatatcaagc atagatttcg
     8641 cggagagccg gacaagaatg gcggcacgac aaagccttcg tttgcgaatg tattctccca
     8701 aaggcacatg catgaaattt cggaacagaa gctggatgtt gcgtctgctg tagccagatt
     8761 tctgtgcgat atcttcgatt gaaatagggt gctcaagatt gcactcaatc cactccagga
     8821 gctgctgtag aatcttctgc ctgatcatca catactccgt taattctttg tcatatcgca
     8881 cattttcgtt atgtcctggg ccctaagtgt atcaaaaaca gcaaggcgca aggaaaaagc
     8941 actgatagcg tctgcttcat tgccccaaaa atagagagat ttctgccctc cattattaat
     9001 gaattttttg cataagtgat atcaaaatcc acatactaat ttgaggttac gttttaacgt
     9061 agactcattg ctcataccta atggagggac tgacagtgga attttccgta ttaagtaaca
     9121 atctgaaaat gccgatgatg ggatttggtg tttttcaggt taccgataaa gacgtgtgca
     9181 aacagtcagt gttgaatgct atccgcacgg gttatcgact catcgacact gcagcggtat
     9241 acggtaatga agatgccgtc ggtgaagccg ttcgtgaagc catatctgaa ggtttatgta
     9301 cccgagaaga gttatttata acgtctaaat tgtgggtgca ggatatgttg aatcaggata
     9361 ttgcagcagc aggtattgaa gcatcattaa aaaaatcggg gctagaatac ttcgatctct
     9421 atttattgca ccaggccatg cgcgattatt ttagtgcgtg gcgtgcactc gaagatgcct
     9481 atgaagaggg caaattaaaa gcgattgggg tttccaattt ctaccctcat gttctggcga
     9541 acttttgtga aacggtaaga gttaaaccga tggtcaacca ggtcgagttg catccctatt
     9601 ttgcccaacc agaggcgctg gcaaccatga agtattataa cgtgcagcct gaagcatggg
     9661 ctccgttagg tggtggacga cataacccct ttgaaaataa tctgcttcag agtattgcag
     9721 atgcccatca aaaatcgatt tctcaggtca ttctgcgttg gaatattcaa cggggagtgg
     9781 tcgttattcc gaaatcgaca catcaacagc gtatcgaaga aaattttgct atttgggatt
     9841 tctcactgac agagaaagaa atggcgcaaa ttagttcgct tgatttgggt tatgttgggg
     9901 aatcggtaaa acattttaat cctgagtttg ttcgtggttg tcttgctgta aaaatacatg
     9961 attgatatta atcacttatt ttacctgaga cgacaagaat cttttatcag gggagtgata
    10021 ttgatcttca ctctgtcata tctccggtaa tatggcgtca ggcttcatta acagaaaggg
    10081 ggcctgacgc ctgaaaaagt gaacaacaga cagtgttcgg attatcaata ttcagttttt
    10141 aacgttgaac tggattcatt actgcgttgt ttaagaatat cccgcgccga atctgccatt
    10201 atcatgacag cacctgccag catcagagta tctttcaata ccaggcgacc agcaccggat
    10261 aaataaggga aaccatgatg agcgtcaccc aatgcgggta cccatgcctc cggggtggtg
    10321 attaaaaatg agagtgttac cagcggcgtg gtaaatgcca tcagcccacc caataaacct
    10381 aaccagcgat tgacaggatt agccaaaacc agcagagcaa taatcacctc cacgacgcca
    10441 agaccgttgg aaaaaccata ggtattatta gccgattgcc atgcccttgc ttctggtttg
    10501 tattcgcctt cgtgagtcag atactgttta tagtcttccg ggtgttcata aaagaacgac
    10561 attagtggac tgtttgcgac gaatggtgta atgctgtctg cctcgtaagg gacaaacttt
    10621 aataacccaa tccacataaa aacaatcgca atactcagac gaatcaatgt caggccaatt
    10681 ttatctcccc gacttaacaa gtgcaggtat ttctccattg taaacatcct tatttataca
    10741 atactgctgt tgcggttgaa ttattatcaa ttcgcatcga tgtgactttc caggatgaag
    10801 cattatattt tctggccata tcagcaatgg catcctccag aactgtcggt gatgctgata
    10861 ctgacgagac gctgatatgt ttcagaatta ttttatcatc tgcattggtg gaaaatgcca
    10921 taacgccaga taatagtgtt gcaaataaaa caggtttttt aaacatataa aataccatca
    10981 atgaagtgat taagaagtta tataataaca gggaattaat aagattcttt tctctgagac
    11041 gccagaatat ttgttctggc gtctgatttt gagtttattt gactaatgaa aatagatcat
    11101 tgagtgattc gctcatcgac ggatgagtaa atatctgatc gcgtaatatg ctataaggca
    11161 gcccggcatc catcaccatt ttcactatat tgatcatctc gtgggagtca acacacagca
    11221 gtgatgcccc taatatacat tgggttttat tatcaacaat cgcttttaat accccacggg
    11281 tatcgttcat cactctggcg cgcggaattg cagctacagg caatgtcacc acctgaatat
    11341 cagcaccact ctctctggct tgttcttctg tcataccaac cctggacagt ggcggtgtca
    11401 taaatacgga ataaggcaca tttttccgat catcagtact acgtctgcct tctcccagca
    11461 attcatcacg cacaatgcgg taatcatcca gtgaaatgta agtaaattgc agcccgccgg
    11521 taacgtctcc catcgcccaa atattgtctg cggtggtatg taattgcttg tcaacgacaa
    11581 ttgccccgcg ctcgtttact gcgatacctg cattttctgg atgtaacgaa gcggtagccg
    11641 gttgacgacc ggaagctatt aacagtgcat ccaccgccag ttgggcgtgc tcgctatgca
    11701 cttgcacttg attttcatgg tgactgattc gctccacatg ggcattgagg ataatatcga
    11761 cgccctgatc gcgtaaaatc gtcgcgatat tatcagcaat atcccgatct tcccgaggca
    11821 aaaacagcga agctgcttct aaaatggtta ccttgctgcc aaaattagcg aacatagagg
    11881 cgaactcaac gccaatatat ccgccgccca aaatacctaa atgcccaggc aattctttta
    11941 gatgaagtaa tccggtgctg tcatatacac caggcgtggt ggtaattcca ggaattggcg
    12001 gaaccacggt ttgtgcaccg gtattaataa aaattttctc gccatgaatt tccagatttc
    12061 cctcaggccg atgaacacgc aggctatgat tattgataaa ctccgcctgg ccgtcgatca
    12121 cgtcgatatt gagcatatct gcaagattat gaaaattctt attacgtaaa aaattaacca
    12181 cttcattttt acgctgtatg gcacggacaa aatctgtgtg ctgctgtgcg tcatgaacca
    12241 atgttttggt tgggatgcag ccgatattaa tacaggtccc gccatacatt gcatttgatt
    12301 gttcgatgag agccacacgc caacctgctt ttgccagcgt gacggctaat gtttttccag
    12361 ccttgccaaa accaataata actgcctgat atttattcat gatgatttcc tgtcgaaacg
    12421 cgttcatttg acatcatgac tatagacgca aaagagcaaa taacatttct tcacaacgct
    12481 tgatattttg tcttatcgtc tggtattttc tttttcttaa tcagaatcac aaaacaaaaa
    12541 tcatgattaa ctatttgatg ttattagatt aattat
//
LOCUS       DADXDL010000118        12043 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.118, whole genome shotgun sequence.
ACCESSION   DADXDL010000118 DADXDL010000000
VERSION     DADXDL010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12043)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12043)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12043
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.118"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            264..497
                     /locus_tag="IRB70_004219"
     CDS             264..497
                     /locus_tag="IRB70_004219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcI/YnfO family protein"
                     /protein_id="HBC0634062.1"
                     /translation="MSTKNRTRRTTIRNIRFPNQMIEQINIALDQKGSGNFSAWVIEA
                     CRRRLCSEKRVSPEANKEKSDITELLRKQIRPD"
     gene            554..964
                     /locus_tag="IRB70_004220"
     CDS             554..964
                     /locus_tag="IRB70_004220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001619138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 family protein"
                     /protein_id="HBC0634063.1"
                     /translation="MAQVAIFKQIFDKVRNNLNYHWFYSELKRHNVSHYIYYLATENI
                     HLVLENDNTVLIKGQGKVVNVRFSKNKCLIEATLKGFKSGELSFYEYRKNLATAGVFR
                     WITNIHENKRYYYTFDNSLLFTENIQNTTQIFPH"
     gene            complement(1316..1468)
                     /locus_tag="IRB70_004221"
     CDS             complement(1316..1468)
                     /locus_tag="IRB70_004221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634064.1"
                     /translation="MPSMIAIILLIILHIWLCRQGGAHFWSESRLNISLLMLDIEHFA
                     RGKGLR"
     gene            complement(1456..1923)
                     /locus_tag="IRB70_004222"
     CDS             complement(1456..1923)
                     /locus_tag="IRB70_004222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HBC0634065.1"
                     /translation="MSRVTAIISALVICIIVCLSWAVNHYRDNAIAYKEQRDNKASEL
                     EKANATITDMQQRQRDADALDDKYTKELADAKAENDALRRKLDNGGRVLVKGKCPVPS
                     SAETSSASGMGNDATVELSPVAGRNVLGIRDGIIRDQTALRTLQEYIRTQCLR"
     gene            complement(1920..2417)
                     /gene="rrrD"
                     /locus_tag="IRB70_004223"
     CDS             complement(1920..2417)
                     /gene="rrrD"
                     /locus_tag="IRB70_004223"
                     /EC_number="3.2.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme RrrD"
                     /protein_id="HBC0634066.1"
                     /translation="MPPSLRKAVAAAIGGGAIAIASVLITGPSGNDGLEGVSYIPYKD
                     IVGVWTVCHGHTGKDIIPGKTYTEAECKALLNKDLATVARQINPYIKVDIPETTRGAL
                     YSFVYNVGAGNFRTSTLLRKINQGDIKGACDQLRRWAYAGGKQWKGLMTRREIEREVC
                     LWGQQ"
     gene            complement(2417..2632)
                     /gene="essD"
                     /locus_tag="IRB70_004224"
     CDS             complement(2417..2632)
                     /gene="essD"
                     /locus_tag="IRB70_004224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HBC0634067.1"
                     /translation="MKSMDKLTTGIAYGTSAGSAGYWFLQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDKRKAARGE"
     gene            complement(2820..3551)
                     /locus_tag="IRB70_004225"
     CDS             complement(2820..3551)
                     /locus_tag="IRB70_004225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001146308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0634068.1"
                     /translation="MLYICSIILVLNSFDVRIGKEDILFKKGSAVLIDYNLKDFFSSN
                     IDHVMIVDVEEKTVNDFFKSNTLSPFSVRRFYPAYLMVECEDFSLLKNLIACLNCDGR
                     TVDFVRNQISLACLAILSSEKIVQSFLFGCLNSLGSKVKAIIHTDISAAWRLCDISSR
                     LYLSESLLKRKLKHEGLSFSKLILEERMVMAERLLSYNLYSVGKVAEICSYENTSYFV
                     SVFRRYFGVPPHQYSSRFFLEKDMM"
     gene            complement(3903..4862)
                     /locus_tag="IRB70_004226"
     CDS             complement(3903..4862)
                     /locus_tag="IRB70_004226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 and DUF1722 domain-containing protein"
                     /protein_id="HBC0634069.1"
                     /translation="MIKKPVIGISGCLAGSAVRFDGGHKRADFLMDKLVEWVTFRPVC
                     PEMAIGLPVPRPALRLVRSTQGNIRMCFSHDQNEDVTERMTEFSRSYMDKLKDVSGFV
                     VCAKSPSCGMERVRVYDENGNRGRKDGVGLFTSTLMEKFSWLPVEEDGRLHDPVLREN
                     FVERVFALHELNHLYKEKLSRRELLAFHSRYKLQLLAHSQAGYKDMGPFVAAIHEWAD
                     LESYFEVYRDKLMAILRKPASRKNHTNVLMHIQGYFSNYLSTRQRKELSEVILNYRSG
                     TLPLLAPLTLLKHYLGEYPNDYLLTQNYFDPYPDELALRLMVN"
     gene            5055..5579
                     /locus_tag="IRB70_004227"
     CDS             5055..5579
                     /locus_tag="IRB70_004227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipocalin family protein"
                     /protein_id="HBC0634070.1"
                     /translation="MKLWPVLTGIALSFTLIACKAPTPPKGVQPITNFDANRYLGKWY
                     EIARLENRFERGLEQVSATYGKRNDGGIRVLNRGYDPTKNKWSESEGKAYFTGDTKTA
                     ALKVSFFGPFYGGYNVIKLDDEYKYALVSGPNREYLWILARTPTIPDKVKADYVRTAQ
                     KLGFNVNELLWVKQ"
     gene            complement(5735..6112)
                     /locus_tag="IRB70_004228"
     CDS             complement(5735..6112)
                     /locus_tag="IRB70_004228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HBC0634071.1"
                     /translation="MRDIQMVLERWGAWAANNHEDVTWSSIAAGFKGLITSKVKSRPQ
                     CCDDDAMIICGCMARLKKNNSDLHDLLVDYYVGGMTFMALARKHGRSDCWVGRMLQKA
                     EGVVEGMLMVLDLRLEMDADCSK"
     gene            complement(6198..6338)
                     /locus_tag="IRB70_004229"
     CDS             complement(6198..6338)
                     /locus_tag="IRB70_004229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlcG family protein"
                     /protein_id="HBC0634072.1"
                     /translation="MMFEFYMAERLRHRWGRLRLYRFPGSVLTDYRILKNYAKTLTGA
                     GV"
     gene            complement(6335..6697)
                     /gene="rusA"
                     /locus_tag="IRB70_004230"
     CDS             complement(6335..6697)
                     /gene="rusA"
                     /locus_tag="IRB70_004230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RusA"
                     /protein_id="HBC0634073.1"
                     /translation="MNTYSITLPWPPSNNRYYRHNRGRTHVSAEGQAYRDNVARIIKN
                     AMLDIGLAMPVKIRIECHMPDRRRRDLDNLQKAAFDALTKAGFWLDDAQVVDYRVVKM
                     PVTKGGRLELTITEMGNE"
     gene            complement(6694..6984)
                     /locus_tag="IRB70_004231"
     CDS             complement(6694..6984)
                     /locus_tag="IRB70_004231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1364 domain-containing protein"
                     /protein_id="HBC0634074.1"
                     /translation="MADLRKAARSRECQVRIPGVCNGNPETSVLAHIRLTGLCGTGTK
                     PPDLIATIACSACHDEIDRRTHFVDAAYAKECALEGMARTQVIWLKEGVIKA"
     gene            complement(6977..7147)
                     /locus_tag="IRB70_004232"
     CDS             complement(6977..7147)
                     /locus_tag="IRB70_004232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634075.1"
                     /translation="MATPLIRVMNGHIYRVPDRRKRKPELKPSEIPTLLGYTASLVDK
                     KWLRLAARRNHG"
     gene            complement(7147..7602)
                     /gene="ybcN"
                     /locus_tag="IRB70_004233"
     CDS             complement(7147..7602)
                     /gene="ybcN"
                     /locus_tag="IRB70_004233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA base-flipping protein YbcN"
                     /protein_id="HBC0634076.1"
                     /translation="MNLPQDGIKLHRGNFTAIGRQIQPYLEEGKCFRMVLKPWREKRS
                     LSQNALSHMWYSEISEYLISRGKTFATPAWVKDALKHTYLGYETKDLVDVVTGDITTI
                     QSLRHTSDLDTGEMYVFLCKVEAWAVNIGCHLTIPQSCEFQLLRDKQEA"
     gene            complement(7599..7700)
                     /locus_tag="IRB70_004234"
     CDS             complement(7599..7700)
                     /locus_tag="IRB70_004234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634077.1"
                     /translation="MRTHNPNSLLPPQMQKCTCDILYPAFDLCGGEA"
     gene            complement(7790..8146)
                     /locus_tag="IRB70_004235"
     CDS             complement(7790..8146)
                     /locus_tag="IRB70_004235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634078.1"
                     /translation="MDTIITWMGDRLLGWITNKSDLRQRAITGLTPAIYSTILYTEKL
                     KRGEPNNPNEEEKLYRLWYEASSQVVDFDRELAKRCLDKSEYWLHSELYSPEKVGELN
                     ISLVGMKATLEGIKHN"
     gene            complement(8608..8931)
                     /locus_tag="IRB70_004236"
     CDS             complement(8608..8931)
                     /locus_tag="IRB70_004236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001307650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634079.1"
                     /translation="MDAGVLVLAVQQYPITKQFTDNELCTLAWLWRAGNVMLITYQNV
                     TPLLQVAEHREAGRFTSIEQEYPQILNKAQAILARETAHVKFRPWQDDKWSRVLPHLR
                     SDRLQ"
     gene            complement(9043..10569)
                     /locus_tag="IRB70_004237"
     CDS             complement(9043..10569)
                     /locus_tag="IRB70_004237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBC0634080.1"
                     /translation="MKKAIAYMRFSSPGQMSGDSLNRQRRLIAEWLKVNSDYYLDTIT
                     YEDLGLSAFKGKHAQSGAFSEFLDAIEHGYILPGTTLLVESLDRLSREKVGEAIERLK
                     LILNHGIDVITLCDNTVYNIDSLNEPYSLIKAILIAQRANEESEIKSSRVKLSWKKKR
                     QDALESGTIMTASCPRWLSLDDKRTAFVPDPDRVKTIELIFKLRMERRSLNAIAKYLN
                     DHAVKNFSGKESAWGPSVIEKLLANKALIGICVPSYRARGKGISEIAGYYPRVISDDL
                     FYAVQEIRLAPFGISNSSKNPMLINLLRTVMKCEACGNTMIVHAVSGSLHGYYVCPMR
                     RLHRCDRPSIKRDLVDYNIINELLFNCSKIQPVENKKDANETLELKIIELQMKINNLI
                     AALSVAPEVTAIAEKIRVLDKELRRASVSLKTLKSKAVSSLGDFHAIDLTSKNGRELC
                     RTLAYKTFEKIIINTDNKTCDIYFMNGIVFKHYPLMKTISAQQAISTLKYMVDGEVYF
                     "
     gene            complement(10627..10734)
                     /locus_tag="IRB70_004238"
     CDS             complement(10627..10734)
                     /locus_tag="IRB70_004238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001302833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634081.1"
                     /translation="MYSFVLSRLWRKKIAIRLLLYIQDNVTLIVFLNKN"
     gene            complement(10826..11158)
                     /gene="emrE"
                     /locus_tag="IRB70_004239"
     CDS             complement(10826..11158)
                     /gene="emrE"
                     /locus_tag="IRB70_004239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMR family multidrug efflux protein EmrE"
                     /protein_id="HBC0634082.1"
                     /translation="MNPYIYLGGAILAEVIGTTLMKFSEGFTRLWPSVGTIICYCASF
                     WLLAQTLAYIPTGIAYAIWSGVGIVLISLLSWGLFGQRLDLPAIIGMMLICAGVLVIN
                     LLSRSTPH"
     gene            complement(11226..11528)
                     /locus_tag="IRB70_004240"
     CDS             complement(11226..11528)
                     /locus_tag="IRB70_004240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein ren"
                     /protein_id="HBC0634083.1"
                     /translation="MTGKEAIIHYLGTHKKFCAQDVAAVTGATVTSINQAAAKMARAG
                     LLAIEGKVWRTVYYRFATREEREGKVSTNLIFKECRQSAAMKRVLRVYKRTSMGTQ"
     gene            complement(11525..>12043)
                     /locus_tag="IRB70_004241"
     CDS             complement(11525..>12043)
                     /locus_tag="IRB70_004241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Replication protein P"
                     /protein_id="HBC0634084.1"
                     /translation="ELNEIRRQWVLAFRENGITTMEQVNAGMRVARRQNRPFLPSPGQ
                     FVAWCREEASVTAGLPNASELVDMVYEYCRKRGLYPDAESYPWKSNAHYWLVTNLYQN
                     MRANALTDAELRRKAADELSCMTARINRGEAIPEPVKQLPVMGGRPLNRAQALAKIAE
                     IKAKFGLKGARV"
BASE COUNT         3469 a         2810 c         2334 g         3430 t
ORIGIN      
        1 agaacggaaa cgccttaaac cggaaatttt tcataaatag cgaaaacccg cgaggtcgcc
       61 gccccgtaac ctgtcggatc gccggaaagg acccgcaaaa tgataataat tatcatctgc
      121 atgtcacaac gtgcatctac gccatcaaac cacgtcaaat aatcaattat gacgcaggta
      181 tcatattaat tgatctgcat caacttaacg taaaaacaac ttcagacaat acaaatcagc
      241 gacactaaat acgggacaac ctcatgtcaa cgaagaacag aacccgcaga acaacaatcc
      301 gcaacatccg ctttcctaac caaatgattg aacaaattaa catcgctctt gatcaaaaag
      361 ggtccgggaa tttctcagcc tgggtcattg aagcctgccg ccggagactg tgctcagaaa
      421 aaagagtttc tcctgaagca aacaaagaaa agagtgacat tactgaattg ctcagaaaac
      481 agatcagacc agattgaagc aatttagata atcgtgcaga ctacgcccct catatcacat
      541 ggaaggtacc acaatggctc aggttgccat ttttaaacaa atattcgata aagtgcgaaa
      601 taatttaaac tatcactggt tttattctga actaaaacgt cacaatgtct cacattacat
      661 ttactattta gctacagaga atattcatct tgttcttgaa aacgataata cggttttaat
      721 aaaaggacag ggtaaggttg taaatgtaag attttcaaaa aataaatgcc ttatagaagc
      781 caccttaaaa ggattcaaat caggagagtt atcattttac gaatacagga aaaatcttgc
      841 tacagcaggg gttttcagat ggattacaaa tatccacgaa aacaaaaggt attactatac
      901 ctttgataat tcattactct ttactgagaa cattcagaac actacacaaa tatttccgca
      961 ctaaatcata acgtccggtt tcttccgtgc cagaaccgga ctcgctggca tgatgaaata
     1021 tgtgtacccg gtaaccccgg tgtgcatcgt ttttgattat tcccgcacac tcgcgcagaa
     1081 ggagttcccc gtcgggctac ggtctctgtt aatacgggaa tacggcgacg atacagcgca
     1141 tgatgtgtca ggcttgaata cctttatcct ttaaaaggga tatcagttaa gttatcccgt
     1201 gtagggtata aaccattatc aaagccactc tgtaggaagt ggcttttgta atggcaataa
     1261 aaagccccgc gaatgcgagg ctaaatcctg gtatttgtaa tgactggttc ttatctcaac
     1321 gcagcccctt accgcgcgca aaatgctcaa tatcaagcat cagcaatgag atgtttaatc
     1381 tggattcact ccagaagtga gcaccaccct gtctacagag ccagatgtga aggatgatga
     1441 gtaaaattat cgctatcatc gaaggcattg cgtcctgatg tattcctgaa gcgttctcag
     1501 tgctgtttgg tcgcggataa ttccgtcccg gataccgaga acgtttcgtc cagcaactgg
     1561 agagagttcg acggtggcat cattgcccat gccggaggcg ctggaggttt cggctgagga
     1621 tggcacaggg cattttcctt tgacgagcac ccgaccacca ttatcaagct tgcgccgaag
     1681 agcatcattt tcagctttcg catcagctaa ctccttcgtg tatttatcat cgagtgcatc
     1741 agcatcacgc tggcgctgct gcatgtcagt aatggtggcg ttcgccttct ccagttcact
     1801 ggccttgtta tcacgctgtt ctttgtaggc gattgcatta tcacggtaat gattaacagc
     1861 ccatgacagg cagacgatga tgcagataac cagagcggag ataatcgcgg ttaccctgct
     1921 cattgttgcc cccacaaaca gacctcacgc tcaatctcac gacgagtcat caggcctttc
     1981 cattgcttac cgccagcgta tgcccagcga cgtagctggt cacatgcgcc cttgatatcg
     2041 ccctggttta ttttgcgaag aagagtagat gttctgaaat tgcctgcgcc cacgttatag
     2101 acgaacgagt aaagagcgcc gcgcgttgtt tccggtatat cgactttgat gtacgggtta
     2161 atttgtctgg ctaccgtggc aaggtcttta ttcaggaggg ctttgcattc tgcttcggta
     2221 tacgttttac cgggaatgat gtcttttcct gtatgcccgt gacatacagt ccatacgcca
     2281 acgatatctt tgtatggtat gtagctgaca ccttccagac catcgttacc acttgggcca
     2341 gtgattaaca ctgatgctat agcaattgct ccgccaccaa tagcagcagc aacggctttt
     2401 cgtaatgatg gaggcattat tcacctctcg cagccttgcg cttatcttct ttaatcttga
     2461 aataaaggtt tgtcaggtac gtcagcaggc caaataccaa gctacccagc acacctattg
     2521 ctgcccactg tgagggcgtg actttatcga gcagctgtaa aaaccagtag ccagcactgc
     2581 ctgcggaggt gccgtaggca atgcccgttg ttaacttatc catggatttc atagcctcac
     2641 ctccgcaaat aacggatggt gtacacggtt cggaacgaag aggaaaggta tagaagttac
     2701 attagcgtaa ggcttgaaca tctattcaaa aagaaaaacg ccgcgattat tctggcgtag
     2761 ctgaaagcat catacaatta tcaaatacga aaattacaaa atcattaaaa cgcatcacgt
     2821 tacatcatgt ctttttctaa aaaaaatctt gatgaatatt gatggggagg aacaccaaaa
     2881 taccttctga aaacacttac aaaatatgac gtgttttcat aactgcatat ctcagcaact
     2941 tttccaacag aatataaatt gtagcttaat aacctttccg ccatcaccat tcgctcttca
     3001 agaattaact tactaaatga taagccttcg tgctttaatt ttctttttaa cagactttca
     3061 ctcagataca gtcttgaaga tatatcacaa agtctccatg ctgcagatat atccgtgtga
     3121 ataatagcct taactttact tcctaaacta ttaagacatc caaataaaaa actttgcact
     3181 attttctctg aagataagat agcaagacat gcaagtgata tttgatttct aacaaaatcc
     3241 acagttctgc catcacaatt caagcatgca atcaagttct ttaacaatga aaaatcttca
     3301 cattccacca tcaagtatgc cggataaaac cttcttacag aaaaaggtga gagtgtgttg
     3361 cttttaaaga aatcattaac tgttttttct tcaacatcta cgatcattac atgatctata
     3421 tttgatgaaa aaaaatcttt taaattgtaa tcaatgagaa cagcacttcc ttttttaaac
     3481 aaaatatctt ctttaccaat tcggacatca aacgagttca acaccaaaat gatagaacat
     3541 atgtatagca tattatccac ctgatatcat tggggttaca ccaggtaagt ataggtggaa
     3601 aatcaatatt cgccagttca acaataagga aaatttcatt gcatcacaag tataaaatta
     3661 tgtatttaac tcacaaagac aaattattaa accaatctgt tatattatat atagctgcgt
     3721 ggaatcataa tattatatat tttgactggc atgtttacta actttaagtt gcatctcaat
     3781 tgtttcttca gcgtaaacag agtttttata caaactgaca ctctgggtat catagtgtag
     3841 tttttacgat tgtaaatatc ctgcatgcag gaactcatcc ttttggatga tatcgcatac
     3901 aattaattta ccatcagtct tagagccagt tcgtccggat agggatcgaa gtaattctgt
     3961 gtaagcaagt aatcattagg atactcaccc agataatgct tcagcagagt caacggcgca
     4021 agaagaggta atgtgccaga acgatagtta agtataacct cgctcaactc tttacgctgg
     4081 cgtgtactta agtagttact aaaatacccc tgtatatgca tcagcacatt cgtgtgattt
     4141 ttacgtgatg caggttttct gagaatcgcc atcagcttat cacgatacac ctcaaagtat
     4201 gattcaaggt ccgcccactc gtgtattgca gccacaaatg gtcccatatc tttatagcct
     4261 gcctgactat gcgccaacaa ctgaagctta taacgactat gaaaagctaa taactctctt
     4321 cttgataatt tctccttgta aaggtgattg agctcatgca aagcaaaaac tctttcaaca
     4381 aaattctcac gaagcactgg atcatgtaat cgcccatcct cttcaaccgg tagccaggaa
     4441 aacttttcca tcaaagtgct cgtaaatagt cccactccat ctttacgacc tcgattacca
     4501 ttttcatcat agacacgcac gcgctccatg ccacagctgg gagatttagc acaaaccaca
     4561 aaccccgata catcctttaa tttgtccata taagaacgac taaactctgt cattctctct
     4621 gtcacatcct cattctggtc gtggctgaaa cacatccgta tatttccttg cgtcgagcgc
     4681 acaagacgta gagcaggacg cggaactggc agccctatag ccatttccgg acatactggt
     4741 ctgaatgtta cccattccac taatttgtcc attaaaaagt cagctctttt gtgaccacca
     4801 tcaaaacgaa cagcagaacc ggccaaacaa ccgctgattc caatcacagg tttttttatc
     4861 atattctccc ccttgactaa ttcattaaca cataaactgt gtagtgcacg gaataaattg
     4921 cctttctggc gtcatcactg acaatttttc tgttatggac tattcctaat atagtatgaa
     4981 agttctttaa gtgatcggtc gtaatcatct atctttcata cttactctca actatcaaaa
     5041 gtacaggatt tattatgaag ttatggcctg tgttgactgg cattgcactc tctttcactc
     5101 ttatagcatg taaggccccg acaccaccta aaggtgtgca gccgattaca aattttgacg
     5161 ccaaccgcta cctcggaaaa tggtatgaaa tagctcgcct cgagaaccgg ttcgaacgtg
     5221 gtctggaaca ggtcagcgct acttatggaa aacggaacga cggagggatt cgtgtactta
     5281 accgtggata cgatccaacg aaaaataaat ggagcgagag cgaaggtaaa gcatacttta
     5341 ctggagatac taaaactgca gcattgaagg tttcgttttt tggccccttc tatggtggct
     5401 ataatgtaat caaactggat gatgagtata agtatgctct tgtcagtggt ccgaacagag
     5461 aatacctatg gattctggca aggaccccaa ctattccaga taaagtaaaa gcagactatg
     5521 tgcgaaccgc tcaaaagttg ggattcaatg tcaatgaatt attatgggtt aaacaataaa
     5581 atccctaccc gaaataatac ttattagaaa aaaaccagcc tttggggagg ctggctaaat
     5641 caggaaacaa gctgttatat gataataact acgttgcgat tccaacattt aaaatgttag
     5701 actaatgaca atcagacagc aacttttcct ttaattattt cgaacaatca gcatccatct
     5761 ccaatcggag atccaacacc atcagcatac cctccactac gccctcagct ttctgaagca
     5821 tcctgccaac ccaacaatca gatcgcccat gcttacgtgc aagcgccata aaagtcatgc
     5881 cgccgacata atagtccacc aataaatcat gcaaatcgct gttgttcttt ttcagacggg
     5941 ccatgcaccc gcaaatgatc atcgcgtcat cgtcacaaca ttgtgggcga gattttactt
     6001 ttgaagtaat taatccctta aaaccggcgg caatggacga ccaggtcaca tcttcatgat
     6061 tattagccgc ccacgctccc caacgctcaa gaaccatctg aatatcacgc atcaacttac
     6121 tccacaaaaa tcagaccaga acgccaatta caagcaaaaa tcaacgaaac agtattagtt
     6181 gattgttatc tctgacttca tactcctgct cctgtcaggg ttttggcgta attcttcagt
     6241 attcggtaat cggtcaaaac agaaccgggg aaacgatata agcgcagacg cccccagcgg
     6301 tggcgaagac gttctgccat ataaaactca aacatcattc attccccatt tcggtgatgg
     6361 tcagttccag cctcccacct ttggtaacag gcatcttcac aacgcggtaa tcaacgacct
     6421 gagcatcatc cagccagaaa cctgctttag tgagtgcgtc aaaagcggct ttttgcagat
     6481 tatccaggtc acggcgacgg cgatccggca tgtggcactc aatgcggatt ttcacaggca
     6541 tagccaggcc gatatccagc attgcgtttt taatgattcg ggcgacgtta tcgcggtatg
     6601 cctgcccctc tgcgctgacg tgcgtgcgcc cgcgattatg gcggtaatag cgattattgc
     6661 tcggaggcca gggtaatgtg atgctgtagg tattcacgcc ttaataaccc cctctttcag
     6721 ccagataacc tgtgttctcg ccataccttc cagcgcgcat tcttttgcat atgcagcatc
     6781 gacaaaatgt gtgcggcggt cgatttcgtc gtggcaggca gaacatgcaa tggtggcaat
     6841 caggtctggc ggtttggtac cggtgccgca caatccagtc agccggatat gtgccagtac
     6901 agacgtttca gggttgccat tacatacgcc agggattctt acctggcatt cccgactacg
     6961 cgctgctttt ctcaaatcag ccatgattcc tccttgctgc cagtcgcaac cattttttat
     7021 caaccaggct ggcggtatat ccgagcagtg ttggtatttc ggaaggcttc agctccggtt
     7081 tacgcttacg acgatctggt actctgtaga tgtgtccgtt catgacacga ataagcggtg
     7141 tagccattac gcctcctgct tgtcgcggag cagctggaac tcgcagctct gcggaatagt
     7201 caggtggcag ccaatattca ccgcccaggc ttcaacctta cacaggaaga catacatctc
     7261 tccggtatca agatcggagg tatggcgtaa cgactggata gtggtgatat caccggttac
     7321 gacatcaacc aggtctttgg tttcataacc gagatatgtg tgtttgagag catcttttac
     7381 ccaagctgga gtagcgaacg ttttacccct gctgatgagg tattcactga tttcgctgta
     7441 ccacatgtgg ctgagtgcat tctgggaaag actgcgtttc tcacgccacg gtttaagcac
     7501 catgcgaaag catttgccct cctccagata aggctggatc tgccgaccga tagcggtgaa
     7561 gttaccgcga tgtaatttga tgccatcttg tgggagattc acgcttcacc tccgcagagg
     7621 tcaaacgctg gatacaatat atcgcaggtg catttctgca tctgtggagg gagaagagag
     7681 tttggattgt gtgtgcgcat aaacgtcccc gtttagcgca gaagtcaccg gagttgttca
     7741 ggctccgatg acatgattat ggcgagttga ttatcgcaaa tcaaaggttt taattgtgct
     7801 ttattccttc aagcgttgcc ttcataccaa ccaaagaaat gtttagctct ccaactttct
     7861 cagggctata taattcagaa tgaagccaat attctgattt atctaaacat cttttagcca
     7921 gctctcgatc aaagtctacg acttgggaag acgcttcata ccaaagtcta taaagttttt
     7981 cttcttcgtt tgggttatta ggctcaccac gttttaattt ttcagtatat aaaattgttg
     8041 aataaatcgc aggagttaat ccagtgattg ccctctgccg cagatcggat ttgtttgtta
     8101 tccaccccaa cagacgatct cccatccatg tgataattgt atccatgctt tagcccttct
     8161 tagtaaatag tgtgtagggc gactgaagga ccgagtttat gctttttcgc attgctttca
     8221 gttagtacac cggtatcgca ccggaaacaa tcctacggca aattggttgt ctgacctctc
     8281 ggtttttcgt gcattaaccg atacccacta cagtctcggc gaaagctgca cacccccagg
     8341 gtgtactggt agcactcggc acagcctagc acgccacttt cttctcacta tccagtctaa
     8401 ttttatcccc tagtcagaca ctcagatgta gtgctccgca gcggcatgcg ggggaataca
     8461 aaaactcgga caaaattggg ccctcctttt tgaatcactc gcggggatgt agttattaat
     8521 acatggaaaa agatctgttt tcaaatccaa cattatatgg tttcaatacc acggggtggc
     8581 tatgtgtttc tcattgttaa ttggaatcta ctgtaatcga tccgaacgta aatgcggcaa
     8641 aactcgactc cacttatcat cctgccacgg ccggaatttt acatgtgccg tttctctggc
     8701 aaggattgcc tgtgccttat tgagtatctg gggatattct tgctcgatag aagtgaagcg
     8761 accagcttca cgatgctccg caacctgaag aagaggagta acgttctggt aggtaattaa
     8821 catcacattc cctgctcgcc ataaccaggc gagtgtgcaa agttcgttat cagtgaattg
     8881 ttttgtgatt gggtattgtt gaactgctag aacgagaacg ccagcatcca ttggcagtct
     8941 ctatagtaaa accatagctc aggacgcttc gttcaggata gataatttta ttgtacttac
     9001 ctaactttct tactatagca cggttgaaaa agtgattatt actcaaaaat aaacctcacc
     9061 atcaaccata tatttgagag tacttatcgc ctgctgggcg gatattgttt tcattaaagg
     9121 atagtgttta aaaacaatgc cattcataaa atagatatca caggttttat tatctgtatt
     9181 gattatgatt ttttcgaatg ttttataggc aagtgtacga catagctctc gcccattttt
     9241 actggttaag tcaatagcat gaaaatcacc aagtgaactc accgctttac tcttcaaagt
     9301 ttttaatgat acagaagccc ttcgtaattc cttatctaat actctgattt tttctgctat
     9361 agcggtaact tcaggcgcaa cagataatgc agcaattaaa ttattaattt tcatctggag
     9421 ctcaataatt ttcaactcta aagtttcatt agcatctttc ttgttttcaa ctggttggat
     9481 tttactacaa ttaaaaagca actcattaat gatattataa tcaaccaaat ctctctttat
     9541 tgatggcctg tcacatcgat gcagtcttct catcggacaa acataatagc catgcaaact
     9601 tccagatacc gcatgaacaa tcatggtatt accacaagcc tcgcacttca taactgttcg
     9661 aagtagattt atcaacatag gatttttgct actattgcta ataccaaaag gtgccaaccg
     9721 aatttcctgt acagcgtaaa acaaatcatc tgatatgact ctgggataat agccagcgat
     9781 ttcacttatt cctttacctc ttgcacgata tgaaggtacg catataccta tcagagcttt
     9841 attcgctaat aatttttcaa ttacagaagg tccccatgca ctttcttttc ctgagaaatt
     9901 ctttacagca tgatcattta aatacttggc tattgcattc aatgagcgcc tttccatcct
     9961 gagtttaaaa attagctcaa tagttttcac cctgtcgggg tctggaacaa aagccgttct
    10021 tttgtcatct aaggagagcc atctcggaca agacgccgtc ataatcgtac ctgattccag
    10081 tgcatcctgc cgttttttct tccatgataa tttaacccga cttgacttta tctcgctttc
    10141 ttcatttgcc ctttgtgcta taagtatggc ttttattaat gaatatggct cattcaaaga
    10201 gtcaatatta tagactgtat tgtcgcaaag agttataaca tcaataccgt gattcaaaat
    10261 caatttcaga cgttcaatcg cttcaccgac tttttctctt gaaagtctgt ccagactttc
    10321 aactaacaat gtagttcctg gcaatatata accatgctct atagcatcta aaaattccga
    10381 aaaagctcct gattgtgcat gctttccttt gaatgcactt aatcctaaat cttcatatgt
    10441 tatggtatca agataataat cactatttac ctttaaccat tcagcaataa gtcttctctg
    10501 tcggtttaat gagtcgccag acatctgacc tggtgatgaa aatcgcatat atgctatggc
    10561 ttttttcatg gtgacacctg ctaacgtatg cttttataaa ccttagtggt gggatataat
    10621 ttttgtttaa tttttattta aaaagacaat taaggtcaca ttatcttgaa tatacaacaa
    10681 taatcgtatt gcaattttct tacgccataa tcttgaaagc acaaaagaat acataaaaaa
    10741 ataaagacat taacaaaaag cataaaacga ggctcatata aatataagag cctccatatt
    10801 ttagtcgttt agaaacaaat tatttttaat gtggtgtgct tcgtgacaat aaattaataa
    10861 ccaacacacc ggcacaaatc aacatcatgc ctataatggc tggcaggtcc agccgttggc
    10921 cgaaaagtcc ccatgacagt aagctaatca ggacaatacc gactcctgac cagatagcat
    10981 aagcaatccc tgtaggaata taagccagcg tctgagctaa taaccagaat gatgcacaat
    11041 aacaaataat tgtaccaaca gatggccata accgtgtaaa accttctgaa aacttcatta
    11101 aggttgtacc aatgacctct gcaagtattg caccaccaag ataaatataa gggttcatag
    11161 aatattcttt cctgttcaaa ctggagagaa ttgtactaca gtttgaactc aactcacctg
    11221 tttcatcatt gtgtacccat tgatgttctt ttatataccc tcaatacccg tttcatcgcg
    11281 gcactctggc gacactcctt aaaaatcaga ttcgtgctca cctttccttc ccgttcttct
    11341 ctggtagcaa accggtaata caccgttcgc cagaccttac cttcgatagc cagaagacct
    11401 gcccgtgcca ttttagccgc agcctgattt atgctggtta ccgttgcgcc tgttaccgcg
    11461 gcaacgtcct gcgcacagaa tttcttatga gtccccaggt aatgaataat tgcctctttg
    11521 cccgtcatac ccttgctcct ttcagcccaa acttagcttt gatttctgcg atcttcgcca
    11581 gagcctgtgc acgatttaga ggtctaccgc ccatgacagg aagttgtttt actggttcag
    11641 gtatagcctc accacggtta attcgtgcgg tcatacagga cagttcatcg gcagccttgc
    11701 gccgtaattc cgcgtcagtc aacgcattgg cccgcatgtt ctgatacagg ttggtaacca
    11761 gccagtagtg cgcgtttgat ttccacggat aagactctgc atccggatac agcccgcgct
    11821 tccggcaata ctcgtaaacc atatcaacca gctcgctggc gtttggcagc ccggcggtaa
    11881 cggatgcttc ttcccggcac caggcgacaa actgcccggg tgatggcagg aatggtcgat
    11941 tctgccgacg ggctacgcgc attccagcgt taacctgttc cattgtggtg atcccgtttt
    12001 cccgaaaagc cagcacccac tggcggcgga tttcgttcag ttc
//
LOCUS       DADXDL010000119        12010 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.119, whole genome shotgun sequence.
ACCESSION   DADXDL010000119 DADXDL010000000
VERSION     DADXDL010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 12010)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12010)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12010
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.119"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            35..637
                     /locus_tag="IRB70_004242"
     CDS             35..637
                     /locus_tag="IRB70_004242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416376.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebB family permuted papain-like enzyme"
                     /protein_id="HBC0634085.1"
                     /translation="MNINYPAEYEIGDIAFTCIGAALFGQISAASNCWSNHVGIIIGH
                     NGEDFLVAESRVPLSTITTLSRFIKRSANQRYAIKRLDAGLTEQQKQRIVEQVPSRLR
                     KLYHTGFKYESSRQFCSKFVFDIYKEALCIPVGEIETFGELLNSNPNAKLTFWKFWFL
                     GSIPWERKTVTPASLWHHPGLVLIHAEGVETPQPELTEAV"
     gene            complement(639..1160)
                     /gene="ruvC"
                     /locus_tag="IRB70_004243"
     CDS             complement(639..1160)
                     /gene="ruvC"
                     /locus_tag="IRB70_004243"
                     /EC_number="3.1.22.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005068993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="crossover junction endodeoxyribonuclease RuvC"
                     /protein_id="HBC0634086.1"
                     /translation="MAIILGIDPGSRVTGYGVIRQVGRQLSYLGSGCIRTKVDDLPSR
                     LKLIYAGVTEIITQFQPDYFAIEQVFMAKNADSALKLGQARGVAIVAAVNQELPVFEY
                     AARQVKQTVVGIGSAEKSQVQHMVRTLLKLPANPQADAADALAIAITHCHVSQNAMQM
                     SESRLNLARGRLR"
     gene            complement(1195..1935)
                     /locus_tag="IRB70_004244"
     CDS             complement(1195..1935)
                     /locus_tag="IRB70_004244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBC0634087.1"
                     /translation="MAGHSKWANTRHRKAAQDAKRGKIFTKIIRELVTAAKLGGGDPD
                     ANPRLRAAIDKALSNNMTRDTLNRAIARGVGGDDDANMETIIYEGYGPGGTAIMIECL
                     SDNRNRTVAEVRHAFSKCGGNLGTDGSVAYLFSKKGVISFEKGDEDTIMEAALEAGAE
                     DVVTYDDGAIDVYTAWEEMGKVRDALEAAGLKADSAEVSMIPSTKADMDAETAPKLMR
                     LIDMLEDCDDVQEVYHNGEISDEVAATL"
     gene            complement(1964..2416)
                     /gene="nudB"
                     /locus_tag="IRB70_004245"
     CDS             complement(1964..2416)
                     /gene="nudB"
                     /locus_tag="IRB70_004245"
                     /EC_number="3.6.1.67"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroneopterin triphosphate diphosphatase"
                     /protein_id="HBC0634088.1"
                     /translation="MKDKVYKRPVSILVVIYAQDTKRVLMLQRRDDPDFWQSVTGSVE
                     EGETAPQAAMREVKEEVTIDVVAEQLTLIDCQRTVEFEIFSHLRHRYAPGVTRNTESW
                     FCLALPHERQIVFTEHLAYKWLDAPAAAALTKSWSNRQAIEQFVINAA"
     gene            complement(2534..4306)
                     /gene="aspS"
                     /locus_tag="IRB70_004246"
     CDS             complement(2534..4306)
                     /gene="aspS"
                     /locus_tag="IRB70_004246"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBC0634089.1"
                     /translation="MRTEYCGQLRLSHVGQQVTLCGWVNRRRDLGSLIFIDMRDREGI
                     VQVFFDPDRADALKLASELRNEFCIQVTGTVRARDEKNINRDMATGEIEVLASSLTII
                     NRADVLPLDSNHVNTEEARLKYRYLDLRRPEMAQRLKTRAKITSLVRRFMDDHGFLDI
                     ETPMLTKATPEGARDYLVPSRVHKGKFYALPQSPQLFKQLLMMSGFDRYYQIVKCFRD
                     EDLRADRQPEFTQIDVETSFMTAPQVREVMEALVRHLWLEVKGVDLGDFPVMTFAEAE
                     RRYGSDKPDLRNPMELTDVADLLKSVEFAVFAGPANDPKGRVAALRVPGGASLTRKQI
                     DEYGNFVKIYGAKGLAYIKVNERAKGLEGINSPVAKFLNAEIIEDILDRTAAQDGDMI
                     FFGADNKKIVADAMGALRLKVGKDLGLTDESKWAPLWVIDFPMFEDDGEGGLTAMHHP
                     FTSPKDMTAAELKAAPENAVANAYDMVINGYEVGGGSVRIHNGDMQQTVFGILGINEE
                     EQREKFGFLLDALKYGTPPHAGLAFGLDRLTMLLTGTDNIRDVIAFPKTTAAACLMTE
                     APSFANPTALAELSIQVVKKAENN"
     gene            4616..5182
                     /locus_tag="IRB70_004247"
     CDS             4616..5182
                     /locus_tag="IRB70_004247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416381.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBC0634090.1"
                     /translation="MLELNAKTTALVVIDLQEGILPFAGGPHTADEVVNRAGKLAAKF
                     RASGQPVFLVRVGWSADYAEALKQPVDAPSPAKVLPENWWQHPAALGATDSDIEIIKR
                     QWGAFYGTDLELQLRRRGIDTIVLCGISTNIGVESTARNAWELGFNLVIAEDACSAAS
                     AEQHNNSINHIYPRIARVRSVEEILNAL"
     gene            5179..5997
                     /locus_tag="IRB70_004248"
     CDS             5179..5997
                     /locus_tag="IRB70_004248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBC0634091.1"
                     /translation="MIYIGLPQWSHPKWVRLGITSLEEYARHFNCVEGNTTLYALPKP
                     EVVLRWREQTTDDFRFCFKFPATISHQAALRHCDDLVTEFLTRMSPLAPRIGQYWLQL
                     PATFGPRELPALWHFLDSLPGEFNYGVEVRHPQFFAKGEEEQTLNRGLHQRGVNRVIL
                     DSRPVHAARPHSEAIRDAQRKKPKVPVHAVLTATNPLIRFIGSDDMTQNRELFQVWLQ
                     KLAQWHQTTTPYLFLHTPDIAQAPELVHTLWEDLRKTLPEIGAVPAIPQQSSLF"
     gene            6050..6445
                     /locus_tag="IRB70_004249"
     CDS             6050..6445
                     /locus_tag="IRB70_004249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310606.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MAPEG family protein"
                     /protein_id="HBC0634092.1"
                     /translation="MVSALYAVLSALLLMKFSFDVVRLRMQYRVAYGDGGFSELQSAI
                     RIHGNAVEYIPIAIVLMLFMEMNGAETWMVHICGIVLLAGRLMHYYGFHHRLFRWRRS
                     GMSATWCALLLMVLANLWYMPWELVFSLR"
     gene            6486..7229
                     /gene="cmoA"
                     /locus_tag="IRB70_004250"
     CDS             6486..7229
                     /gene="cmoA"
                     /locus_tag="IRB70_004250"
                     /EC_number="2.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxy-S-adenosyl-L-methionine synthase CmoA"
                     /protein_id="HBC0634093.1"
                     /translation="MSHRDTLFSAPIARLGDWTFDERVAEVFPDMIQRSVPGYSNIIS
                     MIGMLAERFVQPGTQVYDLGCSLGAATLSVRRNIHHDNCKIIAIDNSPAMIERCRRHI
                     DAYKAPTPVDVIEGDIRDIAIENASMVVLNFTLQFLEPSERQALLDKIYQGLNPGGAL
                     VLSEKFSFEDAKVGELLFNMHHDFKRANGYSELEISQKRSMLENVMLTDSVETHKARL
                     HKAGFEHSELWFQCFNFGSLVALKAEDAA"
     gene            7226..8197
                     /gene="cmoB"
                     /locus_tag="IRB70_004251"
     CDS             7226..8197
                     /gene="cmoB"
                     /locus_tag="IRB70_004251"
                     /EC_number="2.5.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310608.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 5-methoxyuridine(34)/uridine 5-oxyacetic
                     acid(34) synthase CmoB"
                     /protein_id="HBC0634094.1"
                     /translation="MIDFGNFYSLIAKNHLSHWLETLPAQIANWQREQQHGLFKQWSN
                     AVEFLPEIKPYRLDLLHSVTAESEEPLSAGQIKRIETLMRNLMPWRKGPFSLYGVNID
                     TEWRSDWKWDRVLPHLSDLTGRTILDVGCGSGYHMWRMIGAGAHLAVGIDPTQLFLCQ
                     FEAVRKLLGNDQRAHLLPLGIEQLPALKAFDTVFSMGVLYHRRSPLEHLWQLKDQLVN
                     EGELVLETLVIDGDENTVLVPGDRYAQMRNVYFIPSALALKNWLKKCGFVDIRIADVS
                     VTTTEEQRRTEWMVTESLADFLDPHDPSKTVEGYPAPKRAVLIARKP"
     gene            complement(8362..10791)
                     /gene="torZ"
                     /locus_tag="IRB70_004252"
     CDS             complement(8362..10791)
                     /gene="torZ"
                     /locus_tag="IRB70_004252"
                     /EC_number="1.7.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310609.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethylamine N-oxide reductase TorZ"
                     /protein_id="HBC0634095.1"
                     /translation="MTLTRREFIKHSGIAAGALVVTSAAPLPAWAEEKGGKILTAGRW
                     GAMNVEVKDGKIVSSTGALAKTIPNSLQSTAADQVHTTARIQHPMVRKSYLDNPLQPA
                     KGRGEDTYVQVSWEQALKLIHEQHDRIRKANGPSAIFAGSYGWRSSGVLHKAQTLLQR
                     YMNLAGGYSGHSGDYSTGAAQVIMPHVVGSVEVYEQQTSWPLILENSQVVVLWGMNPL
                     NTLKIAWSSTDEQGLEYFHQLKKSGKPVIAIDPIRSETIEFFGDNATWIAPNMGTDVA
                     LMLGIAHTLMTQGKHDKVFLEKYTTGYPQFEEYLTGKSDNTPKSAAWAAEITGVPEAQ
                     IVKLAELMAANRTMLMAGWGIQRQQYGEQKHWMLVTLAAMLGQIGTPGGGFGFSYHYS
                     NGGNPTRVGGVLPEMSAAIAGQASEAADDGGMTAIPVARIVDALENPGGKYQHNGKEQ
                     TYPNIKMIWWAGGGNFTHHQDTNRLIKAWQKPEMIVVSECYWTAAAKHADIVLPITTS
                     FERNDLTMTGDYSNQHIVPMKQAVAPQFEARNDFDVFADLAELLKPGGKEIYTEGKDE
                     VAWLKFFYDAAQKGARAQRVTMPMFNAFWQQNKLIEMRRSEKNEQYVRYGDFRADPVK
                     NALGTPSGKIEIYSKTLEKFGYKDCPAHPTWLAPDEWKGTADEKQLQLLTAHPAHRLH
                     SQLNYAELRKKYAVADREPITIHTEDAARFGIANGDLVRVWNKRGQILTGAVVTDGIK
                     KGVVCVHEGAWPDLENGLCKNGSANVLTADIPSSQLANACAGNSALVYIEKYTGNAPK
                     LTAFDQPAIQA"
     gene            complement(10816..11916)
                     /locus_tag="IRB70_004253"
     CDS             complement(10816..11916)
                     /locus_tag="IRB70_004253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707761.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NapC/NirT family cytochrome c"
                     /protein_id="HBC0634096.1"
                     /translation="MRGKKRIGLLFLLIAVVVGGGGLLLAQKALHKTSDTAFCLSCHS
                     MSKPFEEYQGTVHFSNQKGIRAECADCHIPKSGMDYLFAKLKASKDIYHEFVSGKIDS
                     DDKFETHRQEMAETVWKELKATDSATCRSCHSFDAMDIASQSESAQKMHNKAQKGGET
                     CIDCHKGIAHFPPEIKMDDNAAHELESQTATSVTNGAHIYPFKTSRIGELATVNPGTD
                     LTVVDASGKQPIVLLQGYQMQGSENTLYLAAGQRLALATLSEEGIKALTVNGEWQADE
                     YGNQWRQASLQGALTDPALADRKPLWQYAEKLDDTYCAGCHAPIAADHYTVNAWPSIA
                     KGMGARTSMSENELDILTRYFQYNAKDITEKQ"
BASE COUNT         2753 a         3205 c         2916 g         3136 t
ORIGIN      
        1 cgtatattcg tatctatttc aatggaatga caacgtgaat attaattacc ctgctgaata
       61 tgaaattgga gatatcgcct ttacatgtat aggtgctgcc ttatttggtc aaatatcagc
      121 tgcatcaaat tgttggagta atcacgtcgg gatcattatc ggtcataacg gtgaagactt
      181 cctggttgca gaaagccggg ttcccctctc aaccatcact acgctatccc gttttattaa
      241 acgctctgct aatcaacgct atgctataaa gcgattagac gctgggctga cagaacaaca
      301 aaaacaacga attgttgaac aggttccctc ccggctacgc aaactttacc acaccggttt
      361 taaatacgaa tcttcgcgcc agttctgttc aaaatttgtc tttgatattt ataaagaggc
      421 gctatgtatt ccggtgggtg aaatagagac gtttggagaa ttgttaaata gcaatccgaa
      481 tgcaaaactc actttctgga aattctggtt cctgggttct attccgtggg agcgtaaaac
      541 cgttacgcca gccagtttgt ggcatcatcc gggtttggtg ttgattcatg cggagggagt
      601 ggaaacgcct cagccggaac tgaccgaggc ggtataactt aacgcagtcg ccctctcgcc
      661 aggttcagcc gcgattcgct catctgcatc gcattctgac taacgtggca gtgggtgatg
      721 gcaatcgcca acgcatcagc ggcatccgcc tgtggattag cgggcagttt cagcaaggtg
      781 cggaccatat gctgcacctg gcttttttcg gcgctaccaa tacccaccac cgtttgcttc
      841 acctgacgtg cagcatattc aaataccggc aactcctgat tcaccgccgc cacaatcgcc
      901 acgccgcgcg cctggcccag tttcagggct gagtcagcgt tctttgccat aaagacttgt
      961 tcaatggcga aataatcagg ctggaactgg gtgatgattt ccgtcacgcc cgcatagatg
     1021 agtttcagac gagacggtaa atcatccact ttggtgcgta tgcatccgct acccaggtag
     1081 gacagttgcc tacctacctg gcggatgacg ccgtagccgg tcacgcgcga acccggatca
     1141 atgccgagaa taatagccat cacgcgtctc cgttttgctg tttagcaggc ctcatcagag
     1201 agtcgctgcg acctcatcag agatttcacc gttatggtaa acttcctgca cgtcgtcgca
     1261 atcttccagc atatcgatca gacgcatcag tttcggtgcg gtttctgcat ccatatcagc
     1321 tttggtagac gggatcatgg aaacttccgc gctgtctgct ttcagacctg ccgcttccag
     1381 agcgtcgcgc actttaccca tttcttccca tgcagtgtag acatcaatcg cgccgtcatc
     1441 ataggtcaca acgtcttcag cacctgcttc cagtgctgct tccatgatgg tgtcttcatc
     1501 gcctttctcg aaggagatca cgcctttttt gctgaacaga taagctacgg aaccatcagt
     1561 accgaggtta ccgccacatt tgctgaatgc atgacgcact tcagcaacgg tacggttgcg
     1621 gttgtcagac agacattcaa tcatgattgc cgtgccgcca ggaccgtaac cttcgtagat
     1681 gatggtttcc atgtttgcat catcatcacc gcccacacca cgtgcaattg cgcggttcag
     1741 tgtgtcgcgg gtcatgttgt tagacagtgc tttatcaatt gctgcacgca gacgcgggtt
     1801 agcgtccgga tcgccaccgc ccagcttagc cgcggttacc agctcacgaa tgattttagt
     1861 gaagatttta ccgcgcttag catcctgcgc agctttacga tgtctggtgt tggcccattt
     1921 actatgacct gccataaaaa tatctccaga tagccctgcc tgttcaggca gcgttaatta
     1981 caaactgttc aatcgcctgc cggttgctcc aggacttagt gagcgccgcc gcagcaggcg
     2041 catcaagcca cttgtaagcc agatgttcag tgaaaacgat ctgccgctcg tgcggaagcg
     2101 caagacagaa ccatgattcc gtattacgcg tcacgcccgg cgcatagcga tgacgtaaat
     2161 gtgaaaaaat ttcaaactct accgtgcgct gacagtcaat taaggtcagt tgttcagcga
     2221 caacatcaat ggtgacctct tcctttactt cgcgcatggc agcttgcggc gcggtttcac
     2281 cctcttccac gctgccggtt accgactgcc agaaatcggg atcgtcacgc cgctgcaaca
     2341 tcagcacccg tttcgtatct tgtgcgtaga tgaccactaa gatcgaaacg ggacgcttat
     2401 acactttatc cttcacgctg cctcttcgtt gactgccttc gctcatccca ttcacatagt
     2461 tatctatgct catgggagtt cactcagttg ccgcctcgat gcaacgcgaa tgatttcgtg
     2521 tatttgagtc atatcagtta ttctcagcct tcttcacaac ctgaatgctc agctcagcca
     2581 gtgcagtcgg gttagcaaag ctcggtgctt cagtcatcag acacgctgcc gccgtggttt
     2641 tcgggaaggc gataacgtca cggatattgt cggtgccggt cagcagcatg gtcagacggt
     2701 caagaccgaa tgccagacct gcgtgcggcg gagtaccgta tttcagagcg tcgagcagga
     2761 agccgaattt ctcgcgctgt tcctcttcgt tgatacccag aataccaaac accgtctgct
     2821 gcatatcacc attatggata cgtactgaac caccgcccac ttcgtaacca ttgatgacca
     2881 tatcgtaagc gttcgccacc gcattttccg gtgcagcttt cagttctgca gccgtcatat
     2941 ctttcggtga ggtgaacgga tggtgcattg ccgtcaggcc gccttcaccg tcgtcttcaa
     3001 acatcgggaa gtcgataacc cacagcggtg cccatttgct ttcgtcggtc agaccaaggt
     3061 ctttacccac tttcaggcgc agtgcaccca tcgcgtcggc aacaattttc ttgttgtcgg
     3121 caccgaagaa aatcatatcg ccatcttgcg cggcagtacg atccaggatg tcttcgatga
     3181 tttctgcatt aaggaacttc gctaccgggc tgttgatacc ttccagacct ttcgcgcgtt
     3241 cgttaacttt gatgtaagcc agacctttcg cgccgtagat tttaacgaag ttaccgtatt
     3301 cgtcgatctg cttacgggtc agcgatgcgc cgcccggaac gcgcagagcc gctacgcgac
     3361 ctttcggatc gttcgccgga cctgcaaata cagcaaactc aacagatttc agcagatcag
     3421 caacgtcagt cagttccatc gggttacgca gatccggttt atcagaacca taacggcgtt
     3481 ctgcttccgc aaaggtcatt accgggaaat cgcccagatc cacacccttc acttccagcc
     3541 acagatgacg caccagcgct tccatcactt cacgcacttg cggcgcggtc atgaaagaag
     3601 tttccacatc gatctgagta aattcaggct gacggtcagc acgcaggtct tcgtcacgga
     3661 agcatttaac gatctgatag taacggtcaa aaccggacat catcagcagc tgtttgaaca
     3721 actgcgggga ttgcggcagt gcgtagaatt tacctttgtg cacacgagaa ggcaccaggt
     3781 agtcacgcgc gccttccggc gtggctttgg tcagcatcgg agtttcgatg tcgaggaagc
     3841 cgtggtcatc cataaaacgg cgcaccaggc tggtgatttt agcgcgggtt ttcaggcgct
     3901 gagccatttc cggacgacgc aggtcgaggt agcggtattt cagacgcgct tcttcggtgt
     3961 tgacgtggtt agagtcaagc ggcagaacat ctgcgcggtt gatgatagtc agcgaggacg
     4021 ccagcacttc gatttcgccg gtcgccatat cgcggttaat atttttttcg tcacgcgcac
     4081 gtacggtgcc cgtgacctga atgcagaact cattacgcag ttcagaggcc agctttaacg
     4141 cgtccgcacg atccggatcg aaaaatacct gcacgatacc ttcgcggtcg cgcatatcga
     4201 tgaagatcag gctaccaaga tcacgacgac ggttgaccca accacacaga gtcacctgct
     4261 gccccacgtg ggacaaacgg agctgtccac aatattctgt acgcatgaga tatcccttaa
     4321 cttagctgcc ggcggatgcc ccctgctgcg caggtgacca agtcgcagcg ttagctgtat
     4381 gtcacaactg aatgaaaaaa ggcggctatt atactggaaa ttctgccgca ccgtaagagc
     4441 ctggcccgcg ctggaacgcc tcgttaccac tttatatcgg gcctgaaatc agactctacg
     4501 ccagtttgct ataaaggtgt tgcccgaact cataaaaatt aacaaaattt gtcgttccgc
     4561 catcggctaa tcgcattaag gtgtgaggca cgattttgtt ttttcaggag tcattatgct
     4621 tgaacttaat gctaaaacca ctgcgctggt ggtgatcgat ttacaagaag gcatcttacc
     4681 ttttgccggt ggtccacata ctgccgatga ggtagttaat cgcgccggga agctggcggc
     4741 gaaatttcgc gccagcggtc agcccgtgtt tctggtgcgc gttggctggt ctgccgatta
     4801 cgctgaagca ttaaaacagc cggtcgatgc gccctcaccg gctaaagtgt tgcccgaaaa
     4861 ttggtggcaa catcctgctg cattaggtgc aaccgacagc gatatcgaaa tcatcaaacg
     4921 tcaatggggt gcgttttacg gtacggatct ggagttgcaa ttacgccgcc gaggtatcga
     4981 tacaatagtg ttatgtggga tctcgaccaa tatcggtgtt gaatccaccg cccgcaatgc
     5041 ctgggaactt ggctttaatc tggtgattgc cgaagacgcc tgtagtgccg ccagcgccga
     5101 gcagcacaat aacagtatca accatatcta cccgcgcatc gcccgtgtgc gtagcgtgga
     5161 agagatcctc aacgcgttat gatttacatc ggtctaccgc aatggtcgca tcctaaatgg
     5221 gtgcggttgg ggatcaccag ccttgaagag tatgcccgcc actttaactg cgtggagggc
     5281 aacaccacgc tttacgccct gccgaaaccc gaggttgtcc tgcgctggcg tgagcagacc
     5341 acagatgact tccgcttctg ttttaagttt ccggcgacca tttcgcatca ggcagcatta
     5401 cggcattgcg atgatttagt gactgaattt ttgacccgca tgtcaccgtt ggctccgcgc
     5461 attgggcaat actggctgca actgcctgcc acattcggcc cacgggagct gcctgcgctt
     5521 tggcattttc tcgattctct tcctggcgaa tttaattatg gcgtggaagt ccgccatcca
     5581 cagtttttcg ccaaaggaga agaggaacaa acgcttaatc gcggtttaca tcagcgcggc
     5641 gttaatcggg tgattttaga cagccgcccg gttcatgcag cacgtccaca cagtgaagct
     5701 attcgcgacg ctcaacgaaa aaaacctaaa gttccggtac atgctgtact gacggcgaca
     5761 aatccgctga tccgttttat cggtagtgat gatatgacgc aaaaccggga attatttcag
     5821 gtctggttac aaaaattagc gcagtggcat cagaccacta cgccttatct ttttttacat
     5881 acgccagaca ttgcccaggc accggaactg gtacataccc tgtgggaaga cttacgtaaa
     5941 acgcttccag agatcggagc agttccggct attccacagc aatcttctct tttctgaatt
     6001 tgccacctat catagacagg tgccatcggc cattttaaag ggagtttgta tggtaagcgc
     6061 gctgtatgcc gttttaagtg cgttgttatt aatgaagttc tcttttgatg tcgttcgcct
     6121 gcgaatgcag taccgcgttg cctatggcga cggcggtttt agcgaactgc aaagcgctat
     6181 tcgcattcat ggtaacgcgg tggaatatat tcccatcgcg attgtgctga tgctgtttat
     6241 ggaaatgaat ggcgcagaaa cctggatggt gcatatttgc ggcatcgttt tgcttgctgg
     6301 tcgtctgatg cattattacg gttttcatca ccgtctgttc cgctggcgac gttccggcat
     6361 gagcgccacc tggtgtgcgc tgttgctgat ggtgctggcg aatctttggt atatgccctg
     6421 ggagttggtt ttctccctgc gttagcgcac aatacgccac tttctttttc ccggattttt
     6481 acgttatgtc tcaccgcgac acgctatttt ctgcccctat cgccagactg ggcgactgga
     6541 cctttgatga acgggtagct gaagtcttcc cggatatgat ccagcgttcc gtacccggct
     6601 attccaatat tatttccatg attggtatgt tagccgagcg cttcgttcaa cctggtacgc
     6661 aggtttacga tctgggttgt tctctgggcg cggcgacgct ctcggtgcgt cgcaacattc
     6721 atcatgataa ttgcaaaatt attgccatcg acaactcccc ggcgatgatt gaacgctgcc
     6781 gtcgtcatat tgacgcctat aaagccccta cgccagtaga cgtcattgaa ggtgatattc
     6841 gcgatatcgc cattgaaaac gcatcgatgg tggtgctgaa ttttaccctg caattcctgg
     6901 aaccttccga gcgccaggca ttactggata aaatttatca aggactgaac ccgggcggcg
     6961 cgctggtgct ttcggaaaaa ttcagtttcg aagatgccaa agttggtgaa ctgttgttca
     7021 acatgcacca cgactttaaa cgtgccaacg gttacagcga actggagatc agccagaagc
     7081 gcagcatgct ggaaaacgtg atgctgaccg attccgtgga aacccataaa gcacgcctgc
     7141 ataaagccgg ttttgagcat agtgagctgt ggttccagtg ctttaacttt ggttcactgg
     7201 tggcattaaa agcagaggac gctgcatgat cgactttggt aacttttatt ctctgattgc
     7261 caaaaatcat ctttcacact ggctcgaaac gctgcccgcg cagattgcta actggcagcg
     7321 cgagcagcag cacgggttgt ttaagcagtg gtcaaatgcg gtggagtttc tacctgaaat
     7381 taaaccgtat cgtcttgatt tattgcatag cgttacggca gaaagcgaag agccactgag
     7441 cgcagggcaa attaaacgca ttgaaacgct gatgcgcaac ctgatgccgt ggcgcaaagg
     7501 gccgttctca ctgtatggcg tcaacatcga taccgaatgg cgttccgact ggaaatggga
     7561 tcgtgttctg ccccatcttt ctgatttaac cggacgcacc attctggatg tcggctgcgg
     7621 cagcggttat cacatgtggc gcatgattgg cgcaggcgcg cacctcgcgg tggggatcga
     7681 ccctacgcaa ctttttctgt gccagtttga agcggtgcgt aaactactgg gtaatgatca
     7741 gcgcgcgcat ttgttaccgt taggtattga acaacttccg gcactgaaag cctttgatac
     7801 cgtcttttcg atgggcgtgc tttaccatcg ccgttcaccg ctggagcatc tctggcagtt
     7861 gaaagatcaa ctggtcaatg aaggtgaact ggtgctggaa acgctggtta ttgatggtga
     7921 tgagaacacg gtgctggtac caggcgatcg ttacgcgcaa atgcgtaatg tctatttcat
     7981 cccttccgcg ctggcgctga aaaactggct gaagaagtgt ggttttgtag atatccgcat
     8041 tgcagatgtg agcgttacca ctacagaaga gcaacgacgc accgaatgga tggttactga
     8101 atcgctggcc gatttcctcg acccacatga tccgagtaag acagttgaag gttatccggc
     8161 acctaaacgt gcggtgctga ttgcgcgcaa gccgtaaagg tctggtatta ctgccggatg
     8221 cggcgtgaac gccttatccg gcctacaaaa ccttgctaat tcaatatatt gcagggacta
     8281 tgtaggcctg ataagcatag cgcatcaggc agctttacgt ttgcataacc tcagcgcccg
     8341 tttccgggcg ctattcactt cttatgcctg aatagctggc tgatcaaacg ccgttaactt
     8401 cggcgcattg cccgtatatt tttcgatata caccagcgca gagttaccgg cacaggcatt
     8461 tgccagctgc gagctgggga tatccgccgt taacacgttc gcactgccgt ttttacacaa
     8521 gccattttcc agatctggcc atgcaccttc atgcacgcat accacgcctt ttttgatccc
     8581 gtcagtcacc accgcgcctg tcagaatctg accacgtttg ttccacacac gcaccagatc
     8641 accattcgca ataccaaagc gagcagcatc ttcggtgtga atagtgattg gttcacgatc
     8701 tgcaaccgca tattttttac gcagttccgc atagttaagc tgactatgta aacggtgtgc
     8761 cggatgtgcg gtcagaagct gcaactgctt ctcgtcggcg gtacccttcc actcatcagg
     8821 cgcaagccag gttgggtgtg ccgggcaatc cttatagcca aatttttcca gcgttttgga
     8881 gtaaatctca attttgccgc ttggcgtacc cagcgcattt ttcaccggat cggcgcggaa
     8941 atcaccataa cgaacgtact gttcgttctt ctcgctgcgg cgcatttcga tcagtttatt
     9001 ttgctgccag aaggcattaa acatcggcat agtcacgcgt tgcgcacggg cacctttctg
     9061 agcggcatca tagaaaaatt tcagccacgc cacttcatct ttaccttcgg tatagatctc
     9121 ttttccgcca ggtttcagta attccgcaag atcggcaaac acatcaaaat cgtttcgcgc
     9181 ttcaaattgc ggagcgacag cctgcttcat cggcacaata tgctggttgc tgtaatcacc
     9241 ggtcatcgtc aagtcattgc gctcaaacga tgtggtgatc ggtaatacga tatctgcatg
     9301 tttagcagct gcggtccagt agcattcaga aacgacgatc atctccggtt tctgccatgc
     9361 tttaatcaga cgattagtat cctggtgatg ggtaaagtta ccgccacccg cccaccagat
     9421 cattttgata ttcggatacg tttgctcttt accgttatgc tgatatttgc cgccaggatt
     9481 ttccagcgca tcgacgatac gggcaacagg aatcgccgtc attccgccat catcagcggc
     9541 ctcgctggcc tgtccggcaa tcgccgcaga catttccggc agcacgccgc caacacgtgt
     9601 cgggttgcca ccattggagt aatgataaga gaaaccaaaa ccgccgcccg gtgtaccaat
     9661 ctgccctaac atcgccgcca gcgtcaccag catccagtgt ttctgttcac catattgctg
     9721 gcgctgaatt ccccagcctg ccatcagcat tgtgcgattc gccgccatca gttcagcgag
     9781 tttgactatc tgcgcttccg gtacgccagt aatttccgcc gcccaggccg cgctcttcgg
     9841 agtattatcg ctcttacctg tcagatattc ttcaaactgc ggatacccgg tggtgtattt
     9901 ttcaaggaac actttatcgt gtttgccttg tgtcatcagg gtatgcgcaa tccctaacat
     9961 cagtgccacg tcggtgccca tattcggcgc gatccaggtg gcattatcgc caaagaactc
    10021 aatggtttcg gagcggatag gatcaatggc aatcactggt ttgccagatt ttttcagctg
    10081 atggaagtat tccagccctt gctcatcggt actgctccag gcaattttta aggtattcag
    10141 cgggttcatc ccccacagca ccacaacctg gctgttttcc agaatcagcg gccaggaggt
    10201 ctgctgttca tacacctcta cagaaccgac cacatgcggc atgatcacct gtgctgcccc
    10261 ggttgaataa tcgccgctat gcccggaata accgcccgcg aggttcatat aacgttgcag
    10321 taaggtttgc gctttatgca acacgccaga agagcgccag ccgtaagatc cggcaaaaat
    10381 ggccgatggt ccgttagctt tacgaatacg atcgtgttgc tcatgaatca gttttaatgc
    10441 ttgttcccag ctcacctgta cataggtatc ttcgcctcga cctttcgccg gttgcagtgg
    10501 attatcgaga tagctttttc tcaccatcgg atgctgaata cgcgccgtgg tgtgtacctg
    10561 atccgccgcc gtagactgta aggagttcgg tatggttttc gccagcgcgc ctgtcgaaga
    10621 aacaatcttg ccgtccttca cttctacgtt catcgctccc cagcgtcccg cggtgaggat
    10681 tttaccgccc ttctcttctg cccatgcggg tagcggtgct gccgatgtca ccaccagcgc
    10741 tccagcggca ataccgctgt gtttaataaa ttcacgtctt gttaatgtca taacttcctc
    10801 cctgatcaac gaggatcact gtttctcggt aatatctttg gcgttgtact ggaaataccg
    10861 cgttaaaatg tccagttcgt tttcgctcat gctggttcgt gcccccattc ctttggcaat
    10921 ggacggccac gcattgacgg tgtaatggtc ggcggcaata ggggcatgac aaccagcgca
    10981 ataggtatcg tcaagttttt cagcgtattg ccatagcggt ttacggtccg ctaatgcggg
    11041 atcggtaagc gcaccctgta aagacgcctg acgccattga ttgccgtatt cgtcagcctg
    11101 ccattccccg tttaccgtga gcgccttgat accttcttca cttaatgtgg ctagcgccag
    11161 ccgttgacct gccgccaggt agagcgtgtt ttcactgccc tgcatttgat aaccctgcaa
    11221 cagaacgatc ggctgtttgc cactggcatc aacgacggtg agatcggtac caggattcac
    11281 ggtagccagc tcgcctatgc gagaagtttt gaaaggataa atatgtgcgc cattagtcac
    11341 tgaagtagcg gtctgacttt ccagctcatg cgccgcgttg tcatccattt ttatttctgg
    11401 cggaaaatgg gcaatgcctt tatgacaatc gatacaggtt tcgccgccct tttgtgcttt
    11461 gttatgcatt ttctgcgcag attcactttg cgaggcaata tccatggcat caaaagaatg
    11521 gcaactacgg cacgttgcag agtcagttgc ttttaattct ttccatactg tttcggccat
    11581 ttcctggcga tgagtttcga acttatcgtc actgtctatt ttgccgctaa caaattcatg
    11641 ataaatatct ttagatgctt ttaatttagc aaataaataa tccatccctg actttggaat
    11701 atggcaatcg gcacattccg cacgtatccc tttctggttc gaaaagtgga cagttccctg
    11761 atattcctca aaaggtttac tcatcgagtg gcaggaaagg caaaatgctg tatccgacgt
    11821 tttatgtaag gctttttgcg ccagcaataa cccgccgcca ccaaccacaa ccgctatcag
    11881 caaaaacaat aacccaatgc gttttttccc tcgcatagat tcctctaaat aaattccaga
    11941 acaccgaaat cattgtataa ttaaatacac aacgaattaa ccgcttgcat aactcgacac
    12001 aacactgcct
//
LOCUS       DADXDL010000120        11420 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.120, whole genome shotgun sequence.
ACCESSION   DADXDL010000120 DADXDL010000000
VERSION     DADXDL010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11420)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11420)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11420
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.120"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(40..498)
                     /locus_tag="IRB70_004254"
     CDS             complement(40..498)
                     /locus_tag="IRB70_004254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF986 domain-containing protein"
                     /protein_id="HBC0634097.1"
                     /translation="MTITDLVLILFIAALLAFAIYDQFIMPRRNGPTLLAIPLLRRGR
                     IDSVIFVGLIVILIYNNVTNHGALITTWLLSALALMGFYIFWIRVPKIIFKQKGFFFA
                     NVWIEYSRIKAMNLSEDGVLVMQLEQRRLLIRVRNIDDLEKIYKLLVSTQ"
     gene            complement(553..1404)
                     /gene="manZ"
                     /locus_tag="IRB70_004255"
     CDS             complement(553..1404)
                     /gene="manZ"
                     /locus_tag="IRB70_004255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020804907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IID"
                     /protein_id="HBC0634098.1"
                     /translation="MVDTTQTTTEKKLTQSDIRGVFLRSNLFQGSWNFERMQALGFCF
                     SMVPAIRRLYPENNEARKQAIRRHLEFFNTQPFVAAPILGVTLALEEQRANGAEIDDG
                     AINGIKVGLMGPLAGVGDPIFWGTVRPVFAALGAGIAMSGSLLGPLLFFILFNLVRLA
                     TRYYGVAYGYSKGIDIVKDMGGGFLQKLTEGASILGLFVMGALVNKWTHVNIPLVVSR
                     ITDQTGKEHVTTVQTILDQLMPGLVPLLLTFACMWLLRKKVNPLWIIVGFFVIGIAGY
                     ACGLLGL"
     gene            complement(1417..2217)
                     /gene="manY"
                     /locus_tag="IRB70_004256"
     CDS             complement(1417..2217)
                     /gene="manY"
                     /locus_tag="IRB70_004256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002910918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIC"
                     /protein_id="HBC0634099.1"
                     /translation="MEITTLQIVLVFIVACIAGMGSILDEFQFHRPLIACTLVGIVLG
                     DMKTGIIIGGTLEMIALGWMNIGAAVAPDAALASIISTILVIAGHQSIGAGIALAIPL
                     AAAGQVLTIIVRTITVAFQHAADKAADNGNLTAISWIHVSSLFLQAMRVAIPAVIVAL
                     SVGTSEVQNMLNAIPEVVTNGLNIAGGMIVVVGYAMVINMMRAGYLMPFFYLGFVTAA
                     FTNFNLVALGVIGTVMAVLYIQLSPKYNRVAGAPAQAAGNNDLDNELD"
     gene            complement(2280..3251)
                     /gene="manX"
                     /locus_tag="IRB70_004257"
     CDS             complement(2280..3251)
                     /gene="manX"
                     /locus_tag="IRB70_004257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBC0634100.1"
                     /translation="MTIAIVIGTHGWAAEQLLKTAEMLLGEQENVGWIDFVPGENAET
                     LIEKYNAQLAKLDTTKGVLFLVDTWGGSPFNAASRIVVDKEHYEVIAGVNIPMLVETL
                     MARDDDPSFDELVALAVETGREGVKALKAKPVEKAAPAPAAAAPKAAPTPAKPMGPND
                     YMVIGLARIDDRLIHGQVATRWTKETNVSRIIVVSDEVAADTVRKTLLTQVAPPGVTA
                     HVVDVAKMIRVYNNPKYAGERVMLLFTNPTDVERLVEGGVKITSVNVGGMAFRQGKTQ
                     VNNAVSVDEKDIEAFKKLNARGIELEVRKVSTDPKLKMMDLISKIDK"
     gene            3714..5270
                     /gene="yoaE"
                     /locus_tag="IRB70_004258"
     CDS             3714..5270
                     /gene="yoaE"
                     /locus_tag="IRB70_004258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CNNM family cation transport protein YoaE"
                     /protein_id="HBC0634101.1"
                     /translation="MEFLMDPSIWAGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRD
                     KARLLGLSLALIMRLGLLSLISWMVTLTKPLFTVMDFSFSGRDLIMLFGGIFLLFKAT
                     TELHERLENRDHDSGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
                     VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAI
                     GFSIIIEVFNQIARRNFIRHQSTLPLRARTADAILRLMGGKRQANVQHDADNPMPMPI
                     PEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLGVDEIREQLLSSPHSLF
                     PVCRGELDEIIGIVRAKELLVALEEGVDVAAIASASPAIIVPETLDPINLLGVLRRAR
                     GSFVIVTNEFGVVQGLVTPLDVLEAIAGEFPDADETPEIITDGDGWLVKGGTDLHALQ
                     QALDVEHLADDDDIATVAGLVISANGHIPRVGDVIDVGPLHITIIEANDYRVDLVRIV
                     KEQPAHDEDE"
     gene            complement(5274..6872)
                     /locus_tag="IRB70_004259"
     CDS             complement(5274..6872)
                     /locus_tag="IRB70_004259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416329.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
                     /protein_id="HBC0634102.1"
                     /translation="MQKAQRIIKTYRRNRMIVCTICALVTLASTLSVRFISQRNLNQQ
                     RVVQFANHAVEELDKVLLPLQAGSEVLLPLIGLPCSVAHLPLRKQAAKLQTVRSIGLV
                     QDGTLYCSSIFGYRNVPVVDILAELPAPQPLLRLTIDRALIKGSPVLIQWTPAAGSSK
                     AGVMEMINIDLLAAMLLEPQLPQISSASLTVDNRHLLYGNGLVDSLPQPENNENYQVS
                     SQRFPFTINVNGPGATALAWHYLPTQLPLAVLLSLLVGYIAWLATAYRMSFSREINLG
                     LAQHEFELFCQPLLNARSQQCIGVEILLRWNNPRQGWISPDVFIPIAEEHHLIVPLTR
                     YVMAETIRQRHVFPMSSQFHVGINVAPSHFRRGVLIKDLNQYWFSAHPIQQLILEITE
                     RDALLDVDYRIARELHRKNVKLAIDDFGTGNSSFSWLETLRPDVLKIDKSFTAAIGSD
                     AVNSTVTDIIIALGQRLNIELVAEGVETQEQAKYLRRHGVHILQGYLYAQPMPLRDFP
                     KWLAGSQPPPARHNGHITPVMPLR"
     gene            complement(7003..8367)
                     /gene="sdaA"
                     /locus_tag="IRB70_004260"
     CDS             complement(7003..8367)
                     /gene="sdaA"
                     /locus_tag="IRB70_004260"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase"
                     /protein_id="HBC0634103.1"
                     /translation="MISLFDMFKVGIGPSSSHTVGPMKAGKQFVDDLVEKGLLDSVTR
                     VAVDVYGSLSLTGKGHHTDIAIIMGLAGNEPATVDIDSIPGFIRDVEERERLLLAQGR
                     HEVDFPRDNGMRFHNGNLPLHENGMQIHAYNGDEVVYSKTYYSIGGGFIVDEEHFGQD
                     AANEVSVPYPFKSATELLAYCNETGYSLSGLAMQNELALHSKKEIDEYFAHVWQTMQA
                     CIDRGMNTEGVLPGPLRVPRRASALRRMLVSSDKLSNDPMNVIDWVNMFALAVNEENA
                     AGGRVVTAPTNGACGIVPAVLAYYDHFIESVSPDIYTRYFMAAGAIGALYKMNASISG
                     AEVGCQGEVGVACSMAAAGLAELLGGSPEQVCVAAEIGMEHNLGLTCDPVAGQVQVPC
                     IERNAIASVKAINAARMALRRTSAPRVSLDKVIETMYETGKDMNAKYRETSRGGLAIK
                     VQCD"
     gene            complement(8551..9129)
                     /locus_tag="IRB70_004261"
     CDS             complement(8551..9129)
                     /locus_tag="IRB70_004261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA pyrophosphatase"
                     /protein_id="HBC0634104.1"
                     /translation="MEYRSLTLDDFLSRFQLLRPQINRETLNHRQAAVLIPIVRRPQP
                     GLLLTQRSIHLRKHAGQVAFPGGAVDDTDTSVIAAALREAEEEVAIPPSAVEVIGVLP
                     PVDSVTGYQVTPVVGIIPPDLPYRASEDEVSAVFEMPLAQALHLGRYHPLDIYRRGDS
                     HRVWLSWYEQYFVWGMTAGIIRELALQIGVKP"
     gene            complement(9133..10494)
                     /gene="pabB"
                     /locus_tag="IRB70_004262"
     CDS             complement(9133..10494)
                     /gene="pabB"
                     /locus_tag="IRB70_004262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminodeoxychorismate synthase component 1"
                     /protein_id="HBC0634105.1"
                     /translation="MKTLSPAVITLPWRQDAAEFYFSRLSHLPWAMLLHSGYADHPYS
                     RFDIVVAEPICTLTTFGKETVISESDKRTTTTDDPLQVLQQVLDRADIRPAHNEDLPF
                     QGGALGLFGYDLGRRFESLPEIAQQDIVLPDMAVGIYDWALVVDHQRQTVSLLSHNDV
                     NARRAWLESQQFSPQEDFTLTSDWQSNMTREQYGEKFRQVQEYLHSGDCYQVNLAQRF
                     HATYSGDEWQAFLQLNQANRAPFSAFLRLEQGAILSLSPERFILCDNSEIQTRPIKGT
                     LPRLPDPQEDSKQAEKLANSAKDRAENLMIVDLMRNDIGRVAVAGSVKVPELFVVEPF
                     PAVHHLVSTITARLPEQLHTSDLLRAAFPGGSITGAPKVRAMEIIDELEPHRRNAWCG
                     SIGYLSFCGNMDTSITIRTLTAINGQIYCSAGGGIVADSQEEAEYQETFDKVNKILRQ
                     LEK"
     gene            10568..10747
                     /locus_tag="IRB70_004263"
     CDS             10568..10747
                     /locus_tag="IRB70_004263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YoaH family protein"
                     /protein_id="HBC0634106.1"
                     /translation="MFAGLPSLTHEQQQKAVERIQELMAQGMSSGQAIALVAEELRAN
                     HSGERIVARFEDEDE"
     gene            complement(10867..11165)
                     /locus_tag="IRB70_004264"
                     /pseudo
     CDS             complement(10867..11165)
                     /locus_tag="IRB70_004264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416324.2"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1889 family protein"
BASE COUNT         2874 a         2877 c         2880 g         2789 t
ORIGIN      
        1 taaaaataca ctaaacatag ctttggctaa attcataacc tattgagttg aaacgagaag
       61 cttataaatt ttttccagat cgtcgatatt tcgaacgcgg attaacagcc gacgctgttc
      121 taattgcatc accaacacgc catcttccga caagttcatc gctttgattc ggctatattc
      181 aatccagaca ttggcgaaga aaaaaccttt ttgtttaaag atgatcttcg gaacgcggat
      241 ccagaatata taaaaaccca tcagagccag tgcacttaat aaccatgttg ttattagcgc
      301 gccatgattc gtgacgttgt tatagataag aatgacaatc aatccgacga agataacgct
      361 atcgatgcga ccacgccgga gcaaaggaat tgccagcaga gtggggccgt tacggcgggg
      421 catgatgaac tgatcgtaga tcgcgaaggc caggagtgcg gcgatgaaaa gaatcagtac
      481 caggtccgtg attgtcatta atcctccaga taaaaaaacg gggccaaaag gccccggtag
      541 tgtacatcag tcttacagtc ccagcaggcc gcaagcgtaa ccagcgatac cgatgacgaa
      601 gaagccaacg atgatccaca gcgggttaac ttttttgcgc agtagccaca tacaagcaaa
      661 ggtcagcagc agtggtacca ggcctggcat taactggtcc agaatagtct ggacagtggt
      721 aacgtgttct ttgcccgtct ggtcagtaat gcgagagaca accagcggga tgttgacatg
      781 cgtccacttg ttaactaatg cccccatgac aaacaggccg aggatagacg ccccttccgt
      841 cagtttttgc aggaaaccac cacccatatc tttaacgata tcgatacctt tggagtaacc
      901 atacgctacg ccgtagtaac gggttgccag acgcaccagg ttaaacaaga tgaagaacag
      961 cagcggacct aacaggctgc cgctcattgc gataccggca cccagcgctg caaataccgg
     1021 acgtacggtt ccccagaaga tcgggtcgcc tacaccagcc agcggcccca tcaaaccgac
     1081 tttgataccg ttgatagcac cgtcatcgat ctctgcgcca ttagcacgct gttcttccag
     1141 cgccagggtt acgccgagaa tcggcgcagc cacgaacggc tgggtgttaa agaactccag
     1201 gtgacggcga atagcttgtt tacgagcttc gttgttctca gggtagagtc gacgaattgc
     1261 cggtaccata gagaagcaga aacccagtgc ctgcatacgt tcgaagttcc atgaaccctg
     1321 gaagaggtta gaacgcagga agacgccacg aatatcactt tgagtgagtt ttttctcggt
     1381 ggtagtttga gttgtatcaa ccatttcgct cacctgttag tccagttcgt tatcgagatc
     1441 gttgttacca gctgcctgag caggcgcacc ggctacgcgg ttgtatttcg ggctaagttg
     1501 gatgtagagc actgccataa cagtaccaat cacacccaga gcaaccaggt taaagttggt
     1561 gaatgctgcg gttacgaagc cgaggtagaa gaacggcatc aggtagccag cacgcatcat
     1621 gttgataacc atcgcataac caaccactac gatcatgcca cctgcgatat tcagaccatt
     1681 ggtcaccact tccggaatcg cattcagcat gttctggact tcgctggtac caacagacag
     1741 cgcaacgatg acggccggaa tagccacacg cattgcttgc aggaacagag aagaaacgtg
     1801 gatccaggaa atcgctgtca ggttgccgtt atcagcagcc ttatccgcag cgtgctggaa
     1861 agcaacggtg atagtacgaa cgatgatggt cagtacctgg cccgcagcgg ccagagggat
     1921 tgccagtgcg atacctgcac caatgctctg atgacctgcg ataaccagaa tagtagaaat
     1981 gatggaagcc agagcggcgt caggcgcaac tgcagcaccg atgttcatcc agcccagcgc
     2041 gatcatttcc agcgtaccac cgataataat accggttttc atatcgccaa gaacgatacc
     2101 caccagggta cacgcgatta gcggacggtg aaactgaaat tcatcgagga ttgatcccat
     2161 acctgcgata caggctacga taaataccag cacaatttga agagtggtaa tctccattgt
     2221 acttctcctg tttacgtaag acttaagtgt gaaaactgag tgataatcaa cacaatacgt
     2281 tacttatcga ttttgctgat cagatccatc attttcagtt tcggatcggt ggaaacctta
     2341 cggacttcca gctcaatacc gcgcgcattc agtttcttga acgcctcgat atctttttca
     2401 tcaaccgaaa ccgcgttatt cacctgggtt ttaccctgac ggaatgccat accaccgacg
     2461 ttaacagagg tgattttcac gccgccttca acgagacgct ctacatctgt tgggttggta
     2521 aataacagca ttacgcgttc gccagcatat ttcgggttgt tgtagacgcg aatcattttg
     2581 gcaacatcaa ctacgtgtgc tgttacgccc ggaggtgcaa cctgggtgag cagtgtctta
     2641 cgaacggtat ccgcagccac ttcatcacta acaacaataa tacgggagac attggtttct
     2701 ttggtccagc gggtggcgac ctgaccgtga atcagacggt cgtcgatacg cgcaaggcca
     2761 ataaccatgt agtcgtttgg tcccattggt tttgccggag ttggagccgc ttttggtgct
     2821 gcggcagcgg gtgctggcgc ggctttttca accggtttgg ctttcagcgc tttcacgcct
     2881 tcacggcctg tttctactgc cagcgcaacc agttcatcaa agcttgggtc atcatcacgg
     2941 gccattaacg tttccacgag cattggaatg ttaacgcctg caatgacttc ataatgctct
     3001 ttgtcgacga caatgcggct ggcagcattg aacgggctgc ctccccatgt atcaacgaga
     3061 aacagcacgc ctttagtggt gtcgagtttt gccaactgag cgttgtactt ttcaatcagc
     3121 gtttcggcat tttcacctgg aacgaaatcg atccagccga cgttttcctg ctcgcctaac
     3181 agcatttctg ccgttttaag caactgctct gcagcccaac catgtgtgcc tataacaata
     3241 gcaatggtca cttgctacct cctttattat cgttaacacc tcaacgtgcc agatgtattt
     3301 ttgaatcgtc gtccacaatc gaatcgattc agataagggc tacaaccaaa aacccctgcg
     3361 tttcgcgatt tattttagat atcgaaaaaa ttattttatg tgatgaagat ccgtaattta
     3421 actttcgatt agcagaaatt tcgaaaggta aaatatcctt gtcacattcg tttgcaaagg
     3481 aaggtaaatc tttgccaaat cagatgtgtc tctgatatgt ttaactcccg tttaacaacc
     3541 atggagtata gggcagtagc ccgcagtatg gatcgtcacc gacgtcattt cagcatcagg
     3601 ccttttaacg cctgcctttc tggcactcta tgccgcacct ttcgtttgca ttttgtcgtt
     3661 acgcctgcat tatttctggc gtcgaatagc tattccttaa gcaggagctt gtcatggaat
     3721 tcttaatgga cccctcaatt tgggcggggc tactcacgct tgttgttctg gaaattgtgc
     3781 tgggtatcga taacctggtc ttcatcgcca ttcttgctga caaactgccg ccaaaacaac
     3841 gcgataaagc gcgtttgctg ggattatcat tggcgctgat tatgcgtctg gggctgctgt
     3901 cgctgatttc atggatggtc acgctgacca aaccgctatt taccgtcatg gatttctcct
     3961 tctccggacg cgacctgatt atgttgttcg gggggatatt cttgctgttc aaagcaacaa
     4021 ccgaactgca tgaacggctg gaaaaccgcg atcatgattc cggccacggt aaaggctacg
     4081 ccagtttctg ggtggtcgtc acacagattg tcatccttga cgccgtcttc tcattggatg
     4141 cggtaattac tgcagtaggg atggttaacc atctgccggt gatgatggcg gcggtagtga
     4201 ttgcgatggc ggttatgctg ctggcatcga aaccgctgac gcgattcgtt aaccagcacc
     4261 ccacggtggt ggtgctctgt ctgagcttcc tgttaatgat tggtctgagt ctggtggcag
     4321 aaggtttcgg tttccacatt ccgaaaggtt acctgtatgc cgctattggc ttctcgatca
     4381 tcatcgaagt gtttaaccag attgcgcgtc gcaactttat tcgtcaccag tcgactttgc
     4441 cgctgcgagc gcgtactgcc gatgccatcc tgcgtttgat gggcgggaaa cgtcaggcca
     4501 atgtccagca cgatgccgat aacccgatgc cgatgccgat cccggaaggt gcatttgccg
     4561 aagaagaacg ttacatgatt aacggcgtat tgacgctggc gtcgcgttct ctgcgcggga
     4621 tcatgacgcc gcgcggtgaa ataagctggg ttgacgctaa tctcggggtc gatgaaatcc
     4681 gcgagcaact gctctcttca ccgcacagtc tgttcccggt atgtcgcggt gaactggatg
     4741 aaatcattgg tatcgtacgt gctaaagaac tgctggtggc gctggaagag ggcgttgatg
     4801 tggcggcgat tgcttcggcg tctccggcga ttatcgtccc ggaaaccctc gatccgatca
     4861 acctgctggg cgtgctgcgt cgtgctcgcg ggagctttgt tatcgtgacc aacgagtttg
     4921 gtgtggtaca aggcttggtc acgccgctgg atgtgctgga agccattgcg ggtgaattcc
     4981 cggacgctga cgaaacgccg gaaatcatta ccgacggtga cggctggctg gtaaaaggcg
     5041 gtacagattt gcatgccttg cagcaggcgc ttgatgttga gcaccttgcc gatgacgatg
     5101 atatcgcgac ggtcgcgggc ctcgtgatct cggcaaatgg tcacattccc cgtgtgggcg
     5161 atgtgattga tgtagggcca ctgcatatca ccatcattga agccaatgat tatcgtgttg
     5221 atctggttcg cattgttaaa gagcaaccgg cgcacgatga agatgagtaa gtgttaacgt
     5281 aacggcataa cgggcgtgat atgtccatta tgccgggcgg gcggcggttg gctgcccgcc
     5341 agccatttgg gaaaatcacg tagcggcatc ggctgtgcgt acaaataccc ttgcaaaata
     5401 tgcaccccat gacggcgcaa atacttcgcc tgttcttgtg tttccacacc ctccgccacc
     5461 agttcaatat tcagtctttg ccccagagcg atgatgatat cggtcaccgt cgagttaacc
     5521 gcgtcagaac ctatagctgc ggtaaatgac ttatcaattt tcagcacgtc aggacgtaat
     5581 gtttcaagcc aggaaaacga actgttgccg gtgccgaagt catcaatcgc cagtttgacg
     5641 tttttacgat gcagctcgcg ggcaatccga taatcaacat ccagtaaggc atcgcgttcg
     5701 gtgatttcga ggatcagttg ctgaatcggg tgagcgctaa accagtactg attgagatct
     5761 tttatcagca caccacggcg aaaatggctg ggtgcgacgt taatgccaac atgaaactga
     5821 ctactcattg ggaaaacatg ccgctgacgg atggtttctg ccatcacata gcgggtcagt
     5881 ggcacaatta aatgatgttc ttccgcgata ggaataaaca catccggtga aatccagccc
     5941 tgacgcggat tgttccagcg aagcaaaatc tctacaccaa tacattgctg gctgcgcgca
     6001 ttaagcaaag gctgacagaa caattcgaac tcatgttgcg ccaggcccag attgatttcg
     6061 cgggaaaagc tcatccggta agcggtcgcc agccaggcga tgtagcccac cagtaaactt
     6121 agcagcaccg ccagcggtaa ttgtgttgga agatagtgcc atgccagcgc cgtagccccc
     6181 ggaccattaa cgttaatggt aaaaggaaag cgttgcgaag aaacctggta gttttcattg
     6241 ttttcaggtt gcggaaggga atctaccagc ccattaccat agagcaaatg ccgattgtcc
     6301 accgtcaggc tggcgctact gatttgcggc agttgtggct caagcagcat tgccgccagt
     6361 aagtcgatgt taatcatctc catgacccca gctttgctac tgcccgctgc tggcgtccac
     6421 tgaatcaaaa ccggactgcc tttaatcagg gcacggtcga tcgtcaggcg taaaagtggt
     6481 tgcggtgcag gaagttcagc cagaatgtcc acgacgggca cattgcgata accaaaaatg
     6541 ctggagcaat aaagtgtgcc gtcttgcacc aggccaatgg atcgcacagt ttggagtttt
     6601 gccgcctgtt tacgtaatgg caaatgggcg acagagcagg gcagaccaat cagcggaagc
     6661 aagacttcgc tacctgcctg taggggaagc agtactttat ctaattcctc tacagcgtga
     6721 ttggcgaatt gtactacccg ttgttgattt aagttacgct gtgaaataaa tcgcacgctc
     6781 agggtcgaag cgagcgtaac gagtgcgcaa atcgtacaaa caatcattcg attacggcga
     6841 taggttttaa tgatccgttg tgctttttgc atgcgggcca ccctgtaagc gtatggcgac
     6901 aaacgcctga cgcaacagtg gaagtgtagt ggggaatatt acagcagacg agaaagcggg
     6961 gataaattcg cccatccgtt gcagatgggc gaggataaag tattagtcac actggacttt
     7021 aattgccaga ccaccacgag acgtttcgcg gtacttggcg ttcatgtctt taccggtttc
     7081 gtacatcgtt tcgatgacct tatccagcga gacgcgcggt gcactggtgc gacgcagggc
     7141 catccgcgcg gcgttaatcg ccttgactga cgcaatggcg ttacgttcaa tgcacggcac
     7201 ctgaacttgc cctgcaacag ggtcacaggt cagaccgagg ttgtgctcca tgccaatttc
     7261 cgctgccaca caaacctgtt ccgggctacc gcccaacagc tcggcaaggc ccgcagcagc
     7321 cattgaacag gcaacaccca cttcgccctg gcaaccgact tccgcaccgg aaatagaggc
     7381 gttcatttta tacagtgcac caatcgcgcc cgctgccata aagtaacggg tatagatgtc
     7441 cgggctaacc gattcaataa agtggtcata ataagccagc actgccggaa caatgccaca
     7501 agcaccgttg gttggcgcag ttaccacacg accaccggcg gcgttctctt cgttaactgc
     7561 cagcgcaaac atgtttaccc agtcaatgac attcatcgga tcgttagaca gtttatcgct
     7621 ggaaaccagc atccggcgca gggcagacgc acgacgcggc acgcgcagcg ggcctggcag
     7681 tacgccttcg gtattcatcc cgcgatcgat acatgcctgc atggtttgcc agacatgcgc
     7741 gaaatactcg tcgatctctt tcttgctgtg cagcgccagt tcgttctgca tagcgagacc
     7801 agaaagcgaa tagccggttt cattacagta cgcgagcagt tcggtggcag atttgaacgg
     7861 atacggcacg ctcacttcgt tggcggcatc ctgaccaaag tgttcttcat cgacgataaa
     7921 accgccgccg atggaataat aagttttgct gtagacgact tcatcgccat tataggcgtg
     7981 gatttgcata ccgttttcat gcagcggcag gttaccgtta tgaaaacgca tcccgttgtc
     8041 gcgcgggaaa tccacttcat gccgtccctg tgccagcagc agacgttcgc gctcttctac
     8101 gtcgcgaata aaaccgggaa tactgtcgat atccacggtg gcaggttcgt tacctgcaag
     8161 acccataata atggcgatat cggtgtggtg gcctttaccc gtcagcgaca gtgaaccata
     8221 aacgtccacg gcaacgcgag taacgctatc cagtaagcct ttttcgacca gatcatcgac
     8281 gaactgttta cccgccttca taggccctac ggtatgggaa gatgagggac caatccccac
     8341 cttaaacatg tcgaatagac taatcacgat aatactcctg acaaggtgac tggacttcca
     8401 gtaacgaact aataacagcg catagtgtaa gagggaacgc ggcgactggc ttaactattc
     8461 acatgaatta aactaatcaa aaaccgcgat ttaactaata ttgcgatgat tgtctcaagt
     8521 agtgttttgt agatgtaaag ataagtatag tcagggtttc acaccaattt gcagcgccag
     8581 ttcacgaatt atgcctgcgg tcattcccca tacaaaatac tgttcgtacc aggacagcca
     8641 tacccgatgt gaatcgccac ggcggtagat atctaaagga tgataacgac ccagatgtaa
     8701 tgcctgggcg agcggcattt caaagacggc agagacttca tcttcactgg cgcgatacgg
     8761 cagatcgggc gggataatgc cgaccactgg ggttacctga tagccagtga cgctatcgac
     8821 gggcggcagc acgccaataa cttcaacggc agaaggcggt atagcgacct cttcttcagc
     8881 ttcgcgcagc gcggcggcga taacggatgt gtccgtgtca tcgactgcac ctccagggaa
     8941 tgccacttgt ccggcgtgtt tacgcagatg aatcgaacgc tgagtcagca acaaccccgg
     9001 ttgcggtcga cggacgatgg ggattaacac ggcagcctga cgatgattta gggtttcccg
     9061 gttaatttgc gggcgcaaaa gttgaaagcg cgataaaaaa tcatcaagcg tcaggctacg
     9121 gtattccacg tcttacttct ccagttggcg taatatctta ttaactttat caaaagtttc
     9181 ctgatattcc gcttcttcct ggctatcggc gacaattcca ccccccgcag agcagtaaat
     9241 ttgtccgtta atggcagtca gcgtgcggat agtaatgctg gtgtccatgt tgccgcaaaa
     9301 gctcaaatag ccaatgctgc cgcaccaggc atttcgtcgg tgcggttcca gttcgtcgat
     9361 aatttccata gcccgtactt tcggagcccc ggttattgag ccaccaggaa aagctgcgcg
     9421 cagcagatcg ctggtgtgta actgttctgg tagccgcgcc gttatggtgc tgaccagatg
     9481 atgcacggca gggaagggtt ccaccacgaa cagctctggt acttttaccg aaccggctac
     9541 ggcaacgcga ccgatatcat tacgcattaa atcaacaatc atcagatttt cagcgcgatc
     9601 tttcgctgag ttcgccagtt tttctgcttg tttgctatct tcctgaggat cgggcaggcg
     9661 tggtagcgtg cctttaatcg ggcgggtctg gatttcacta ttatcacaaa ggataaaccg
     9721 ctctggcgaa aggcttaaaa tcgcgccctg ttcaagacgt aaaaaagcgc taaatggcgc
     9781 gcggttggcc tgattaagct gaaggaatgc ctgccattca tcgccagaat aggtcgcatg
     9841 aaaacgctgg gcgagattca cctgatagca atcaccgctg tgcagatatt cctgtacctg
     9901 gcgaaatttt tcgccgtact gctcgcgggt catattggat tgccagtcgg aagtgagcgt
     9961 gaaatcttcc tgtggggaga attgctggct ttccagccat gcccgacggg cattgacatc
    10021 attatgactc agcaaagaaa ctgtttgacg ctggtggtcg acaaccagcg cccagtcgta
    10081 gatacccact gccatatccg gcagaacgat atcttgctgc gcaatttctg gcagtgactc
    10141 aaaacggcgg cccagatcgt agccaaacaa ccccagcgcg ccgccctgaa atggcaaatc
    10201 ttcgttatgc gctgggcgaa tgtctgcgcg atccagcacc tgctggagca cctgtagcgg
    10261 gtcatcagtg gtcgttgtac gtttatcgct ttcactaata acggtttctt taccgaaagt
    10321 agttaaagtg caaattggct cggcgaccac aatatcaaag cggctatacg gatgatcggc
    10381 atagccggag tgtaaaagca tcgcccacgg caggtggctt aagcgggaga aataaaattc
    10441 agcggcgtcc tgacgccagg gtaaagtaat cacagcggga gataacgtct tcatcagtcc
    10501 tgactctact ggctatgtgc cgggtagcat gaaataatta gcgccaacaa tttagcagga
    10561 gttaacaatg tttgcaggtt taccttcact cacccatgaa cagcagcaaa aagctgtcga
    10621 gcggatccag gaactgatgg ctcaagggat gagcagcggc caggcaatcg cgttggtggc
    10681 agaagagctg cgtgccaacc attccggcga gcgaatcgtg gcgcgttttg aggatgaaga
    10741 cgagtaacac actaacccgt atcgctttcg ttatagaagc cgatggttat ttgattgtga
    10801 gaaaaaggac gcttttcata tgtgattaaa agcgtcctga cccatttatg ctgatgtaaa
    10861 tttaacttag accagtgctt ttagttcttc ctgcatatat gttgaaaagt attcaggatt
    10921 tttaatcaca atgcgttcac cagactccat ttttttgccc atccaaccat tttttccgtg
    10981 aaccccgggt tccagccttc ctggtcagct cgcgccgtaa tatcagcggc actcgcgggt
    11041 actcccagtt ctttcaaata tttaaagatt cccttcgccg tgctttcatt catcgaactt
    11101 ggtgttggtg ctgatacatc catggcacca atgaaatcca gggctttatc tattacagca
    11161 ggcatattct tatccttaaa attaaccatg ttatcgataa ggctatatat gaccttaatt
    11221 tgcatctaat atcaaaggga ttataacgat atggcacgag ttaacctgtt gacattcagg
    11281 tgttttaaag gtagcagctc atggtgtgtt atccagtaag agggagaaaa ttaacggtca
    11341 gttctcacgc tataaccaga ttgttcagcc aagaaagaaa accagagttg ctaatcagaa
    11401 ggcgaacaca acggcatggt
//
LOCUS       DADXDL010000121        11035 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.121, whole genome shotgun sequence.
ACCESSION   DADXDL010000121 DADXDL010000000
VERSION     DADXDL010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 11035)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11035)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11035
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.121"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..631)
                     /locus_tag="IRB70_004265"
     CDS             complement(<1..631)
                     /locus_tag="IRB70_004265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016242982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric reductase-like transmembrane
                     domain-containing protein"
                     /protein_id="HBC0634107.1"
                     /translation="MKKANLTGTLVCFVACLIFLSSGDIFREKPIALIWFLRQNILFF
                     TGTLAWCLMTLTMCLSLRSSWLNKVLGGLDKAWRLHKWAGICAIAFAFAHWLDEKLPQ
                     LFVAFGWLTHPGKIVDINLTPVQENWLHAGLLAGECAMFIIIAMVCVSLSKRVPYHLF
                     HLVHRLFPVFYLAIAFHVFTALFKSYWWETPAAYLLILITIPGVFAAFIS"
     gene            complement(693..953)
                     /locus_tag="IRB70_004266"
     CDS             complement(693..953)
                     /locus_tag="IRB70_004266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000023744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1471 domain-containing protein"
                     /protein_id="HBC0634108.1"
                     /translation="MSIKQNLFAALFLCTLTGHAFAATEIHKPDNNLEQLSKVSMSTH
                     NSNPAGVESQIKEKAEELQASNYYISSFSGKNYIHATVIFYK"
     gene            complement(970..1599)
                     /locus_tag="IRB70_004267"
     CDS             complement(970..1599)
                     /locus_tag="IRB70_004267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001571861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBC0634109.1"
                     /translation="MKILHIDSSPMLKHSSSRKLSQALVEALCQRFAQATIIHRDVGL
                     TPPPHLREETFLALCGKAECENAQIQQEVNDIHAAIDELASCDVLIIGAPMINHSVSS
                     GLKTWIDQVCHAGLTFRFTSAGAVGLLTDKPTFIVSTRGGIYCDEAHLALDHQESYLQ
                     ATLKLMGITNTHILRAEGVDKTQPGRELAEQNALAQIPDLITQVFNHYL"
     gene            1700..2596
                     /locus_tag="IRB70_004268"
     CDS             1700..2596
                     /locus_tag="IRB70_004268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001604818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0634110.1"
                     /translation="MIDWNDYYYFALIADEGSYSQAALRAGVSKSVLSRRMAALEERL
                     GVRLIQRTTRRLALTAAGEQFAVECRALVAQGERARAVVMAAQESPQGMLRVSAPVFM
                     AETWFGEFVSEFIARWPLAKVQMLAINRPVDMVAEGIDIALVTASGALADSTLHYKKL
                     HTQADILVASSQWLARHPQVKAIDDLNRVDGILRLTNNGGSQWQLINGEQEITLQPEA
                     RLQTNNIRVMLQAVLGGNGVALLPQFACKQGLANGELVRLFAPWSGIPRPLYALFAGR
                     KGMPAIARYFMDELTTRLANGV"
     gene            2652..3311
                     /gene="rpiA"
                     /locus_tag="IRB70_004269"
     CDS             2652..3311
                     /gene="rpiA"
                     /locus_tag="IRB70_004269"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBC0634111.1"
                     /translation="MTQDELKKAVGWAALQYVQPGTIVGVGTGSTAAHFIDALGTMKG
                     QIEGAVSSSDASTEKLKSLGIHVFDLNEVDSLGIYVDGADEINGHMQMIKGGGAALTR
                     EKIIASVAEKFICIADASKQVDILGKFPLPVEVIPMARSAVARQLVKLGGRPEYRQGV
                     VTDNGNVILDVHGMEILDPIAMENAINAIPGVVTVGLFANRGADVALIGTPDGVKTIV
                     K"
     gene            3567..4799
                     /gene="serA"
                     /locus_tag="IRB70_004270"
     CDS             3567..4799
                     /gene="serA"
                     /locus_tag="IRB70_004270"
                     /EC_number="1.1.1.95"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBC0634112.1"
                     /translation="MAKVSLEKDKIKFLLVEGVHQKALESLRAAGYTNIEFHKGALDD
                     EQLKESIRDAHFIGLRSRTHLTEDVINAAEKLVAIGCFCIGTNQVDLDAAAKRGIPVF
                     NAPFSNTRSVAELVIGELLLLLRGVPEANAKAHRGVWNKLAAGSFEARGKKLGIIGYG
                     HIGTQLGILAESLGMYVYFYDIENKLPLGNATQVQHLSDLLNMSDVVSLHVPENPSTK
                     NMMSAKEISLMKPGSLLINASRGTVVDIPALCDALASKHLAGAAIDVFPTEPATNSDP
                     FTSPLCEFDNVLLTPHIGGSTQEAQENIGLEVAGKLIKYSDNGSTLSAVNFPEVSLPL
                     HGGRRLMHIHENRPGVLTALNKIFAEQGVNIAAQYLQTSAQMGYVVIDIEADEDVAEK
                     ALQAMKAIPGTIRARLLY"
     gene            5029..5088
                     /gene="ibsC"
                     /locus_tag="IRB70_004271"
     CDS             5029..5088
                     /gene="ibsC"
                     /locus_tag="IRB70_004271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin IbsC"
                     /protein_id="HBC0634113.1"
                     /translation="MMRLVIILIVLLLISFPAY"
     gene            complement(5189..5791)
                     /locus_tag="IRB70_004272"
     CDS             complement(5189..5791)
                     /locus_tag="IRB70_004272"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311809.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBC0634114.1"
                     /translation="MTQLPELPLTLSRQEIRKMIRQRRRTLTPEQQQEMGQQAATRMM
                     TYPPVVMAHTVAVFLSFDGELDTQPLIEQLWRAGKRVYLPVLHPFSAGNLLFLNYHPQ
                     SELVMNRLKIHEPKLDVRDVLPLSRLDVLITPLVAFDEYGQRLGMGGGFYDRTLQNWQ
                     HYKMQPVGYAHDCQLVEKLPVEEWDIPLPAVVTPSKVWEW"
     gene            complement(5812..5995)
                     /gene="ssrS"
                     /locus_tag="IRB70_004273"
     ncRNA           complement(5812..5995)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="IRB70_004273"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(6037..6366)
                     /gene="zapA"
                     /locus_tag="IRB70_004274"
     CDS             complement(6037..6366)
                     /gene="zapA"
                     /locus_tag="IRB70_004274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBC0634115.1"
                     /translation="MSAQPVDIQIFGRSLRVNCPPDQRDALNQAADDLNQRLQDLKER
                     TRVTNTEQLVFIAALNISYELAQEKAKTRDYAASMEQRIRMLQQTIEQALLEQGRITE
                     KTNQNFE"
     gene            6534..7112
                     /gene="ygfB"
                     /locus_tag="IRB70_004275"
     CDS             6534..7112
                     /gene="ygfB"
                     /locus_tag="IRB70_004275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708672.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0149 family protein YgfB"
                     /protein_id="HBC0634116.1"
                     /translation="MSIQNEMPGYNEMNQYLNQQGTGLTPAEMHGLISGMICGGNDDS
                     SWLPLLHDLTNEGMAFGHELAQALRKMHSATSDALQDDGFLFQLYLPDGDDVSVFDRA
                     DALAGWVNHFLLGLGVTQPKLDKVTGETGEAIDDLRNIAQLGYDEDEDQEELEMSLEE
                     IIEYVRVAALLCHDTFTHPQPTAPEVQKPTLH"
     gene            7138..8463
                     /gene="pepP"
                     /locus_tag="IRB70_004276"
     CDS             7138..8463
                     /gene="pepP"
                     /locus_tag="IRB70_004276"
                     /EC_number="3.4.11.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Xaa-Pro aminopeptidase"
                     /protein_id="HBC0634117.1"
                     /translation="MSEISRQEFQRRRQALVEQMQPGSAALIFAAPEVTRSADSEYPY
                     RQNSDFWYFTGFNEPEAVLVLIKSDDTHNHSVLFNRVRDLTAEIWFGRRLGQDAAPEK
                     LGVDRALAFSEINQQLYQLLNGLDVVYHAQGEYTYADEIVNSALEKLRKGSRQNLTAP
                     ATMIDWRPIVHEMRLFKSPEEIAVLRRAGEITALAHTRAMEKCRPGMFEYHLEGEIHH
                     EFNRHGARYPSYNTIVGSGENGCILHYTENESELRDGDLVLIDAGCEYKGYAGDITRT
                     FPVNGKFTLAQREIYDIVLESLETSLRLYRPGTSMQEVTGEVVRIMVSGLVKLGILKG
                     DVDELIAQNAHRPFFMHGLSHWLGLDVHDVGVYGQDRSRILEPGMVLTVEPGLYIAPD
                     AEVPEQYRGIGIRIEDDIVITETGNENLTASVVKKPEEIEALMAAARKQ"
     gene            8460..9638
                     /gene="ubiH"
                     /locus_tag="IRB70_004277"
                     /gene_synonym="visB"
     CDS             8460..9638
                     /gene="ubiH"
                     /locus_tag="IRB70_004277"
                     /gene_synonym="visB"
                     /EC_number="1.14.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-octaprenyl-6-methoxyphenyl hydroxylase"
                     /protein_id="HBC0634118.1"
                     /translation="MSVIIVGGGMAGATLALAISRLSHGALPVHLIEATAPESHAHPG
                     FDGRAIALAAGTCQQLARIGVWQSLADCATAITTVHVSDRGHAGFVTLAAEDYQLAAL
                     GQVVELHNVGQRLFALLRKAPGVTLHCPDRVANVARTQSHVEVTLESGETLTGCVLVA
                     ADGTHSALATVCGVDWQQEPYEQLAVIANVATSVAHEGRAFERFTQYGPLAMLPMSDG
                     RCSLVWCHPLERREEVLSWSDEKFCRELQSAFGWRLGKITHAGKRSAYPLALTRAARP
                     ITHRTVLVGNAAQTLHPIAGQGFNLGMRDVMSLAETLTQAQERGEDMGDYGVLCRYQQ
                     RRQRDREATIGVTDSLVHLFANRWGPLVVGRNIGLMAMELFTPARDVLAQRTLGWVAR
                     "
     gene            9661..10863
                     /gene="ubiI"
                     /locus_tag="IRB70_004278"
                     /gene_synonym="visC"
     CDS             9661..10863
                     /gene="ubiI"
                     /locus_tag="IRB70_004278"
                     /gene_synonym="visC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent 2-octaprenylphenol hydroxylase"
                     /protein_id="HBC0634119.1"
                     /translation="MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQRVPEPLAADA
                     PPQLRVSAINAASEKLLTRLGVWQDILSRRASCYHGMEVWDKDSFGHISFDDQSMGYS
                     HLGHIVENSVIHYALWNKAQQSSDITLLAPAELQQVAWGENETFLTLKDGSMLTARLV
                     IGADGANSWLRNKADIPLTFWDYQHHALVATIRTEEPHDAVARQVFHGEGILAFLPLS
                     DPHLCSIVWSLSPEEAQRMQQAGEDEFNRALNIAFDNRLGLCKVESERLVFPLTGRYA
                     RQFAAHRLALVGDAAHTIHPLAGQGVNLGFMDAAELIAELKRLHRQGKDIGQYIYLRR
                     YERSRKHSAALMLAGMQGFRDLFSGTNPAKKLLRDIGLKLADTLPGVKPQLIRQAMGL
                     NDLPEWLR"
     gene            complement(10937..11020)
                     /locus_tag="IRB70_004279"
     CDS             complement(10937..11020)
                     /locus_tag="IRB70_004279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634120.1"
                     /translation="MSKNTKSKNHDIRKYNAKTEVKLVYFK"
BASE COUNT         2659 a         2681 c         2980 g         2715 t
ORIGIN      
        1 gcgaaatgaa agccgcaaag acgcccggaa tagtaattaa aattaataaa tacgcagcag
       61 gagtttccca ccagtatgat ttaaacaaag cagtaaacac atgaaaggca attgccagat
      121 aaaagacggg gaacaaacgg tgaacaagat gaaataaatg atagggaact cttttgctaa
      181 gagatacgca aaccatcgct ataataataa acattgcgca ttcacccgct aacagtcccg
      241 catgaagcca attttcttgt actggcgtca ggttaatatc aacgatttta ccagggtgag
      301 taagccagcc aaaggcgacg aataactggg gtaatttttc atccagccag tgggcgaaag
      361 caaacgctat ggcgcatatt cctgcccact tatgtaatcg ccatgcttta tccagaccgc
      421 ccagcacttt gttaagccat gatgaacgca acgataaaca catcgtcagc gtcatcagac
      481 accacgcaag agttcccgta aaaaagagta tgttttgtcg aaggaaccat attagagcga
      541 ttggcttttc acgaaaaata tcaccggacg acaaaaaaat aaggcatgcg acaaagcaaa
      601 ccaacgtacc tgtaagatta gcttttttca ttttttattt cattttggca gaggagcatg
      661 gaataattcc atgcttccgt taaacagagg ggctatttat agaaaattac agtggcgtgg
      721 atataatttt taccggagaa agaactgatg tagtaattgc tggcttgtaa ctcttccgct
      781 ttctctttga tttggctttc aacgcccgct ggattgctat tgtgtgtgga catgctcact
      841 tttgataact gttcaagatt attgtccggt ttgtgtatct cggttgcggc aaatgcgtgt
      901 cctgtgagag tgcaaagaaa taatgcggca aataaatttt gcttaataga cataataact
      961 ccttttatat taaagataat gattaaatac ttgtgtaata agatcaggga tttgcgctaa
     1021 tgcattttgc tcggcgagtt cgcgtcccgg ttgggttttg tcgacgcctt ccgcgcgcaa
     1081 aatatgtgta ttggtaatgc ccattaattt cagtgtggct tgcagataac tttcctgatg
     1141 atccagcgcc agatgtgctt catcgcaata gataccgccg cgcgtcgaga caataaacgt
     1201 cggtttatcc gtcagtaacc caacggcacc agcggaagta aaacgaaacg ttaaaccagc
     1261 atgacagacc tgatctatcc aggttttgag gccagatgaa acgctgtgat taatcatcgg
     1321 cgcgccaata atgagcacat cgcacgatgc cagttcatca atagcagcgt ggatatcatt
     1381 cacctcctgc tgaatttgtg cgttctcgca ttccgcttta ccgcaaagcg ccagaaaggt
     1441 ttcttcacgc aaatggggtg ggggcgtcag gccaacgtcg cgatgaataa ttgtggcttg
     1501 cgcgaaacgt tggcaaagcg cttctaccag cgcctggctt aatttccgcg aacttgaatg
     1561 cttaagcatt ggactgctgt cgatatggag aattttcatg ggtttgctct catttctgcg
     1621 atgagagaag tttaactgtt gttgacatgg tgattaaata gtcataattg aacttcattg
     1681 ttgtgaaaat agaacaatca tgatcgactg gaatgattac tactactttg ccctgattgc
     1741 cgatgaaggc agctacagcc aggcggcgct gcgtgcgggt gtgtcgaaat cggtattaag
     1801 ccgtcgaatg gcagcgctgg aagagcgcct cggcgtgagg cttattcagc gaactacgcg
     1861 gcgtctggcc ctgacggcgg caggggaaca gtttgctgtc gagtgtcggg cgctggtggc
     1921 tcagggggaa cgggccagag cggtggtgat ggccgcccag gaaagcccac agggaatgct
     1981 gcgcgtcagc gcgccggtat ttatggctga aacatggttt ggtgagttcg tcagtgaatt
     2041 tatcgcccgc tggcccctgg cgaaggtgca aatgctggca attaatcgcc cggtggatat
     2101 ggtcgctgaa ggcattgata ttgcgctggt tacggcttcc ggcgcgcttg cggactcgac
     2161 gctgcattat aaaaaattac atactcaggc cgatatttta gttgccagtt cgcagtggct
     2221 ggcccgccat ccgcaggtga aggccattga cgatcttaac cgcgtcgacg ggatccttcg
     2281 cctgacaaac aatggcggga gccagtggca gttaattaat ggcgaacagg agattacgtt
     2341 gcagcctgag gcgcgtttgc agacaaataa cattcgtgtc atgttgcagg cagtgcttgg
     2401 tgggaatggc gtggcgttat tgcctcaatt tgcctgtaaa caggggcttg cgaacggtga
     2461 actggtgcgc ctgtttgcac cgtggagcgg catacccaga ccgttgtatg ctttatttgc
     2521 cgggcgaaag gggatgcccg ccattgcgcg atattttatg gatgagttaa ccacgcggct
     2581 tgccaacggg gtctgaatcg ctttttttgt atataatgcg tgtgaaattt cataccacag
     2641 gcgaaacgat catgacccag gatgaattga aaaaagcagt aggatgggcg gcacttcagt
     2701 atgttcagcc cggcaccatt gttggtgtag gtacaggttc caccgccgca cactttattg
     2761 acgcgctcgg tacaatgaaa ggccagattg aaggggccgt ttccagttca gatgcttcca
     2821 ctgaaaaact gaaaagcctc ggcattcacg tttttgatct caacgaagtc gacagccttg
     2881 gcatctacgt tgatggcgca gatgaaatca acggccacat gcaaatgatc aaaggcggcg
     2941 gcgcggcgct gacccgtgaa aaaatcattg cttcggttgc ggaaaaattt atctgtattg
     3001 ccgacgcctc caagcaggtt gatattctgg gcaaattccc gctgccagta gaagttatcc
     3061 cgatggcacg tagtgcagtg gcgcgccagc tggtgaaact gggcggtcgt ccggaatacc
     3121 gtcagggcgt ggtgaccgat aacggcaacg tgatcctcga cgtccacggc atggaaatcc
     3181 ttgacccgat agcgatggaa aacgccataa atgcgattcc tggcgtggtg actgttggct
     3241 tgtttgctaa ccgtggcgcg gacgttgcgc tgattggcac acctgacggt gtcaaaacca
     3301 ttgtgaaatg atctgacggg ggaacctccc ccgttaaaaa aattctcttc attaaatttg
     3361 gtgacatgtg tcacgttttt acctggctat tgtcgattgc tctaaataaa tcctctaaac
     3421 cagcatattc atccaagaaa tacctttgcg tgatatttcc tcaacatcgc gacgcaaacg
     3481 ttcatattgc cgcaatatta ttttttgata tgttgaaagg cggatgcaaa tccgcacaca
     3541 acatttcaaa agacaggatt gggtaaatgg caaaggtatc gctggagaaa gacaagatta
     3601 agtttctgct ggtagaaggc gtgcaccaaa aggcgcttga aagccttcgt gcagcgggtt
     3661 acaccaacat cgaatttcac aaaggcgcgc tggatgatga acaattaaaa gaatccatcc
     3721 gcgatgccca cttcatcggc ctgcgatccc gtacccatct gactgaagac gtgatcaacg
     3781 ccgcagaaaa actggtcgct attggctgtt tctgtatcgg aacaaaccag gttgatctgg
     3841 atgcggcggc aaaacgcggt atcccggtat ttaacgcacc gttctcaaat acgcgctctg
     3901 ttgcggagct ggtgattggc gaactgctgc tgctattgcg cggcgtgccg gaagccaatg
     3961 ctaaagcgca ccgtggcgtg tggaacaaac tggcggcggg ttcttttgaa gcgcgcggca
     4021 aaaagctggg tatcatcggc tatggtcata ttggtactca attgggcatt ctggctgaat
     4081 cgctgggaat gtatgtttac ttttatgata ttgaaaacaa actgccgctg ggcaacgcca
     4141 ctcaggtaca gcatctttct gacctgctga atatgagcga tgtggtgagt ctgcatgtac
     4201 cagagaatcc gtccaccaaa aatatgatga gtgcgaaaga gatttcacta atgaagcccg
     4261 gctcgctgct gattaatgct tcgcgcggta ctgtggtgga tattccggcg ctgtgtgacg
     4321 cgctggcgag caaacatctg gcgggggcgg caatcgacgt attcccgacg gaaccggcaa
     4381 ccaatagcga tccatttacc tctccgctgt gtgaattcga caacgtcctt ctgacgccac
     4441 acattggcgg ttcgactcag gaagcgcagg agaatatcgg cctggaagtt gcgggtaaat
     4501 tgatcaagta ttctgacaat ggctcaacgc tctctgcggt gaacttcccg gaagtctcgc
     4561 tgccactgca cggtgggcgt cgtctgatgc acatccacga aaaccgtccg ggcgtgctaa
     4621 ctgcgctcaa caaaattttt gccgagcagg gcgtcaacat cgccgcgcaa tatctacaaa
     4681 cttccgccca gatgggttat gtagttattg atattgaagc cgacgaagac gttgccgaaa
     4741 aagcgctgca ggcaatgaaa gctattccgg gtaccattcg cgcccgtctg ctgtactaat
     4801 tccccttctc tgaaaattaa cgggcaggtc actgacttgc ccgatttttt tatcccttct
     4861 ccacaccgtt gccgcattgc gcattctact ttgcgagtct gctccagaaa ataaatcaaa
     4921 gtcagatcaa tgcgttgtgt ttatttaatg gggatttacg atggcagggc agcatggggc
     4981 tgtaacggta aagccctcac cgaagcgagg gcttgaagga gaagggttat gatgcgactt
     5041 gtcatcatac tgattgtact gttactcata agtttcccag cttattaaca gtcagtctca
     5101 ggggaggagt catcctccct tacccttact cactaaatta ggttaaagaa tcaacgatgt
     5161 caatcagggc gatgcaggtg tgtcgccctt accactccca gactttcgac ggtgtaacca
     5221 ccgcaggaag agggatatcc cactcttcaa cggggagttt ttccaccaac tgacaatcat
     5281 gcgcataacc caccggttgc attttatagt gctgccagtt ttgtaaggtc cgatcataaa
     5341 aaccaccgcc cattcccagg cgctgaccgt actcatcaaa ggcgaccagc ggtgtgatca
     5401 acacgtctaa tcgggaaagg ggtagcacgt cacgcacatc cagttttggc tcatggatct
     5461 tcaacctgtt catcaccagt tcgctttgcg gatggtaatt caggaacagc aaattaccgg
     5521 cactaaaggg atgcaaaact ggaagatata cgcgcttacc ggcgcgccag agttgttcta
     5581 tgagtggctg ggtgtcgagt tcgccatcaa aagagaggaa tacagcgacc gtatgtgcca
     5641 tcaccaccgg gggataagtc atcatccggg tagcggcttg ttgacccatt tcctgctgtt
     5701 gttccggcgt taacgtacga cgacgttgcc gaatcatttt gcggatttct tgtcgggata
     5761 atgtcagtgg gagttcgggt agttgcgtca tggctggtgc cagataagaa gggaatctcc
     5821 gagatgccgc cgcaggctgt aacccttgaa cccttggttc aaggtgaatg tgtcgtcgca
     5881 gttttaaggc ttctcggacg gaccgagcat gctcaccaac cgcggagcgc cacattcttg
     5941 tggtatgaaa tatcggctca ggggactggc ccgcttgcga acatctcaga gaaattttgt
     6001 cttcacggtt actctaccac agtaaaccga aaagtgtcat tcaaagtttt ggttagtttt
     6061 ttcggtgatg cgaccttgtt caagtaacgc ttgttctatg gtctgctgca gcatccgaat
     6121 acgctgttcc atacttgccg cgtagtcacg agtcttcgct ttttcttgcg ctaactcata
     6181 gctgatattc aatgcggcaa tgaagaccaa ctgttcagta tttgtgactc tagtgcgttc
     6241 tttcagatct tgcaaccgtt ggttcagatc gtccgctgcc tgattcaacg catccctttg
     6301 gtcaggcggg cagttcacac gcagtgaacg gccaaaaatt tggatatcga cgggttgtgc
     6361 agacatgcca ccttcctgct gattgactgc gctgccttcg tctttagacc catggtctgc
     6421 gaaggggcga cactatagct accctgatga gaagagacaa gcccttttct ggtccaccag
     6481 ggcccaaagt ggtagcatat catgaatatt cctccctttg acgacgaatg cttatgtcta
     6541 tacagaacga aatgcctggt tacaacgaaa tgaaccagta tctgaaccaa caagggacgg
     6601 gtctgacccc tgctgagatg catggtttaa tcagtgggat gatatgtggc ggtaacgatg
     6661 acagctcatg gctgccgcta cttcacgacc tgacgaacga aggcatggct ttcggtcatg
     6721 agctggcaca ggcactgcgt aaaatgcact ctgccaccag cgatgccctg caggatgacg
     6781 gcttcctttt tcagctttat ctgcctgatg gcgatgatgt cagcgttttc gatcgggctg
     6841 atgcgctggc aggttgggtc aatcacttcc tgcttggtct tggcgttacg caaccgaagc
     6901 tggacaaagt gaccggagaa accggtgaag ccatcgacga tctgcgtaac atcgcgcagc
     6961 tgggctacga cgaagacgaa gatcaggaag agcttgaaat gtcgcttgaa gagatcatcg
     7021 aatacgttcg tgttgccgcg ctgttatgcc acgacacctt tactcatccg caaccgaccg
     7081 cgccagaagt acaaaaaccg actctacact aaaaacaaaa aacgtaagga gagtgttatg
     7141 agtgagatat cccggcaaga gtttcagcgt cgccgtcagg ccctggtgga gcaaatgcaa
     7201 cccggcagcg ccgcgctgat ttttgctgca ccagaagtaa cacgtagcgc cgacagcgaa
     7261 tacccctatc gtcagaacag tgacttctgg tacttcaccg gctttaacga accggaagcg
     7321 gtgctggtgc tgattaaaag cgacgacact cataaccaca gcgttttgtt taaccgcgtt
     7381 cgcgacctga cggcagagat ctggtttggt cgtcgcttag gccaggatgc cgcgccagag
     7441 aaactgggcg ttgaccgcgc actggcattc agcgaaatca atcagcaact ttatcaactg
     7501 cttaatggtc tggatgtggt ttatcacgct cagggcgaat atacctatgc tgatgaaatc
     7561 gtgaacagcg cgctggaaaa gctgcgtaaa ggctcgcgac agaatctcac tgccccggca
     7621 acgatgatcg actggcgtcc cattgttcat gaaatgcgcc tgttcaaatc accagaagag
     7681 attgccgtac ttcgccgcgc gggggaaatc accgccctgg cgcatacccg ggcgatggaa
     7741 aaatgccgtc cgggaatgtt cgagtaccac ctggaaggcg aaattcacca cgaatttaac
     7801 cgccacggtg cgcgctatcc ttcctataac accattgtcg gcagcggtga aaatggctgc
     7861 attctgcact acaccgaaaa cgagagtgaa ctgcgcgacg gtgacctggt gttgattgac
     7921 gcgggttgtg aatacaaagg ttacgcgggc gatattaccc gcaccttccc ggtcaacggc
     7981 aaattcaccc tggcccagcg tgaaatctac gacattgtgc tggagtctct tgaaaccagc
     8041 ctgcggctgt atcgtccggg aacttccatg caggaagtca ctggtgaagt ggtgcgcatc
     8101 atggttagcg gcctggtaaa actcggcatc ctgaaaggtg atgttgatga actgatcgct
     8161 cagaacgccc atcgtccttt ctttatgcat ggccttagcc actggttagg actggatgtt
     8221 catgacgttg gtgtttatgg tcaggatcgc tcgcgtattc tggaaccggg gatggtactg
     8281 accgtagagc ctggtctgta tattgcgccg gatgcagaag tgccagaaca atatcgcggt
     8341 atcggcattc gtattgaaga cgacattgtg attaccgaaa ccggcaacga aaacctcacc
     8401 gccagcgtgg tgaaaaagcc ggaagaaatc gaagcgttga tggctgctgc gagaaagcaa
     8461 tgagcgtaat catcgtcggt ggcggcatgg cgggcgcgac gctggcgctg gctatttccc
     8521 ggttaagtca cggggcgctg ccggtacatt tgattgaagc gactgcgcca gagtcacatg
     8581 ctcatccggg ctttgatgga cgggctattg cgctggcggc gggtacctgt cagcaactgg
     8641 cgcgcatcgg cgtctggcaa tctctggctg attgcgcaac cgccatcact accgtgcatg
     8701 tcagcgatcg tggtcatgcc ggattcgtca ccctcgccgc agaagattac caactggcgg
     8761 cgctggggca ggttgtcgaa ttgcataatg tcgggcaacg gctgtttgca ttgctgcgca
     8821 aagcacctgg cgtaacgctg cattgtcctg atcgcgtggc taacgttgcc cgtactcaga
     8881 gtcacgttga agtgacgctg gagagtggcg agacgctgac gggctgcgtg ctggtagccg
     8941 ctgatggcac ccattcagcg ttagccaccg tgtgcggcgt tgactggcag caggagcctt
     9001 acgaacaact ggctgtgatt gccaacgttg cgacttccgt tgcgcatgaa gggcgcgctt
     9061 ttgaacgctt tacacaatat ggcccgctgg cgatgttgcc gatgtctgac ggacgctgtt
     9121 cgctggtctg gtgtcatcca ctggaacggc gcgaagaggt actgtcttgg agcgacgaga
     9181 agttttgccg tgaactccag tcggcctttg gttggcgact tgggaaaatt acccacgctg
     9241 gtaaacgcag tgcttatccg ctggcgttaa cccgcgccgc cagacctatt acccatcgta
     9301 ccgtgctggt gggcaatgcg gcgcaaactc tgcacccgat tgccgggcaa gggttcaacc
     9361 tcggtatgcg agatgtcatg agccttgcgg aaaccctgac tcaggcgcag gagcgcggag
     9421 aagacatggg tgattacggc gtattgtgcc gttatcagca gcgtcgacag cgcgatcgcg
     9481 aagcaaccat cggcgtcacg gacagccttg tacatctttt tgccaaccgt tgggggccgc
     9541 tggttgtcgg gcgcaacatc gggctgatgg caatggaatt attcacccca gcacgcgatg
     9601 tgctggcgca gcgcaccctc gggtgggtgg cgcgttgaag gcggttttaa ggaataaaca
     9661 atgcaaagtg ttgatgtagc cattgttggc ggcggcatgg tggggctggc ggttgcctgc
     9721 ggcttgcagg gtagcggctt acgcgttgcc gtactggagc agcgcgtacc ggaacctctg
     9781 gcggcggatg caccaccaca actgcgcgtt tcggctatca atgccgccag cgaaaaatta
     9841 ctcacccgtc ttggcgtctg gcaggacatt ctctctcgta gggccagttg ttatcacggt
     9901 atggaagtgt gggacaaaga cagttttggt cacatttcgt ttgacgatca aagcatgggc
     9961 tatagccatc ttgggcatat cgttgaaaac tcggtgattc actacgcgct gtggaacaaa
    10021 gcgcagcagt cgtcagatat cactctgttg gcccccgcag aattacagca ggtcgcctgg
    10081 ggagaaaatg aaaccttcct gacgttgaaa gatggcagta tgttaacggc gcgtctggtg
    10141 attggcgcgg acggcgctaa ttcctggttg cgcaacaaag ccgatattcc gctgactttc
    10201 tgggattatc agcatcacgc gctggtagcg accattcgca cggaagaacc gcatgatgcg
    10261 gtggcgcggc aggtttttca tggcgaaggc attctggcct ttttgccgct tagcgatccg
    10321 catctttgct cgattgtctg gtcactgtcg ccagaggaag cgcagcggat gcagcaggca
    10381 ggcgaagacg aatttaatcg cgcgttaaat atcgcttttg ataatcgcct gggcttatgc
    10441 aaggttgaaa gtgagcgcct ggtgttcccg ctaacggggc gttatgcgcg ccagtttgcc
    10501 gcacaccgtc tggcgctggt gggcgacgcc gcgcatacta ttcacccgct ggcggggcag
    10561 ggggtaaatc tcggctttat ggatgctgca gagctgattg ctgaactgaa acggttgcat
    10621 cgtcagggta aagacatcgg gcagtacatt tacctgcgtc gctatgagcg tagccgtaag
    10681 cacagtgcgg cgctgatgct ggctggtatg cagggattcc gcgatctgtt ttccggtacc
    10741 aatccggcga aaaaattgct gcgtgatatt ggtttaaaac tggccgacac gcttcctggc
    10801 gttaaaccac aacttatccg ccaggcaatg ggattaaacg atttgcctga atggctgcgt
    10861 taaaaatttc tcctctgttg tttatttgat acccatcaca ctttcatctc ccggtttttt
    10921 cgccgggaga ttttcctcat ttgaaataaa ctaatttcac ctccgttttc gcattatatt
    10981 ttctaatgtc atgatttttt gatttagtgt tttttgacat ttttttagtt cttaa
//
LOCUS       DADXDL010000122        10981 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.122, whole genome shotgun sequence.
ACCESSION   DADXDL010000122 DADXDL010000000
VERSION     DADXDL010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10981
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.122"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(47..1096)
                     /locus_tag="IRB70_004280"
     CDS             complement(47..1096)
                     /locus_tag="IRB70_004280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBC0634121.1"
                     /translation="MLNTVKISSCELINADCLEFIRSLPENSVDLIVTDPPYFKVKPE
                     GWDNQWKGDDDYLKWLDQCLAQFWRVLKPVGSLYLFCGHRLASDIEIMMRERFSVLNH
                     IIWAKPSGRWNGCNKESLRAYFPATERILFAEHYQGPYRPKDAGYAAKGSALKQHVMA
                     PLISYFRDARAALGITAKQIADATGKKNMVSHWFSASQWQLPNESDYLKLQSLFARVA
                     EEKHQRGELEKPHHQLVDTYTSLNRQYVELQSEYKHLRRYFGVTAQVPYTDVWTHKPV
                     QFYPGKHPCEKPAEMLQQIISASSRPGDLVADFFMGSGSTVKAALALGRRAIGVELET
                     GRFEQTVREVQDLIV"
     gene            complement(1247..1444)
                     /locus_tag="IRB70_004281"
     CDS             complement(1247..1444)
                     /locus_tag="IRB70_004281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309806.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrmB family transcriptional regulator"
                     /protein_id="HBC0634122.1"
                     /translation="MLKQQDMTETARVVFNELSVTEPATVGEIAQNTYLSRERCQLIL
                     TQLVMAGLADYQFGCYRRLPQ"
     gene            complement(1658..2347)
                     /locus_tag="IRB70_004282"
     CDS             complement(1658..2347)
                     /locus_tag="IRB70_004282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antiterminator"
                     /protein_id="HBC0634123.1"
                     /translation="MNNQYLQFVREQLMIATADLSGSTKGQLEAWQENAMFDTGRYRR
                     KKIRYRDEVTGKMITRDNPPIPGKQSLAKGASIPLVSPVEFLTSSWRRAVLSLEEHHK
                     AWLLWCYSGSICWEYQIAITQWVWNEFKTRYGTRKIAGKTQERVKKLIWLAAQDVRGW
                     ITGCEVYQRQELARLCGVKPDNWSHNYANYWREMCDIFKSLDRESVICTVKIRAQQKA
                     IFSRRDIAKVN"
     gene            complement(2344..2703)
                     /locus_tag="IRB70_004283"
     CDS             complement(2344..2703)
                     /locus_tag="IRB70_004283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBC0634124.1"
                     /translation="MLIDLVLPYPPTVNTYWRRRGSTYFVSKVGERYRRDVALIVRQQ
                     QLKLNLSGRPAIEIIAEPPDKRRRDLDNILKAPLDVLTHAGLLIDDEQFDEINIVRGQ
                     LVPGGRLGIKITELEYA"
     gene            complement(2716..3765)
                     /locus_tag="IRB70_004284"
     CDS             complement(2716..3765)
                     /locus_tag="IRB70_004284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HBC0634125.1"
                     /translation="MRVLLRPVLVPELGLVIVKPGRESMPVFHNTRVLVEPEPKSMRN
                     LPSGVVPAVRQPLAEDKSLLPFFSDERVIRAAGGAGALSDWLLRHVKSCQWPHGDYHH
                     SETVIHRYGTGAMVLCWHCDNQLRDQTSESLEQLAHQNLSAWMIDVIRHAMNGTQERE
                     LSLAELSCWAACNQVVDALPEAVARRSLGLPAEKIRSVYRESDIVPGEQTAISILKQR
                     TKNIALPLHVHQQQNPPQEKTVVSIAVDPESPESFMKRPKRRRWVNEKYTRWVKTQPC
                     ACCGKPADDPHHLIGHGQGGMGTKSHDIFTLPLCREHHNEFHANPLAFEEKHGSQVDL
                     IFRFLDHAFATGVLG"
     gene            complement(3767..4045)
                     /locus_tag="IRB70_004285"
     CDS             complement(3767..4045)
                     /locus_tag="IRB70_004285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634126.1"
                     /translation="MAHDTKLHNSDNSAVFASRRGRCFHAFKSDWYQHPPCTEEQAEW
                     LIQCYRRRGYEVKKALSLDYRHWIISVRLPYSERPPRPSRTFQQRIWR"
     gene            complement(4212..4367)
                     /gene="hokD"
                     /locus_tag="IRB70_004286"
     CDS             complement(4212..4367)
                     /gene="hokD"
                     /locus_tag="IRB70_004286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HBC0634127.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVF
                     TAYEPEE"
     gene            5122..6350
                     /locus_tag="IRB70_004287"
     CDS             join(5122..5437,5437..6350)
                     /locus_tag="IRB70_004287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558215.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBC0634128.1"
                     /translation="MIDVLGPEKRRRRTTQEKIAIVQQSFEPGMTVSLVARQHGVAAS
                     QLFLWRKQYQEGSLTAVAAGEQVVPASELAAAMKQIKELQRLLGKKTMENELLKEAVE
                     YGRGKKVDSARALIARGWGVSLVSRCLRVSRAQLHVILRRTDDWKDGRRSRHSDDTDV
                     LLRIHHVIGELPTYGYRRVWALLRRQAELDGMPAINAKRVYRIMRQNALLLERKTAVP
                     PSKRAHTGKVAVKESNQRWCSDGFEFRCDNGEKLRVTFALDCCDREALHWAVTTGGFD
                     SETVQDVMLGAVERRFGNELPASPVEWLTDNGSCYRANETRQFARMLGLEPKNTAVRS
                     PESNGIAESFVKTIKRDYISIMPKPDGLTAAKNLAEAFEHYNEWHPHSALGYRSPREY
                     LRQQASNGLSDNRCLEI"
     gene            complement(6626..6802)
                     /locus_tag="IRB70_004288"
     CDS             complement(6626..6802)
                     /locus_tag="IRB70_004288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000753063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634129.1"
                     /translation="MADFGSTKYNVSFEEWHELLMDYAELRGGSAADAEAWRDDYEAG
                     KTPVEAYCDEWGDE"
     gene            complement(6795..6977)
                     /locus_tag="IRB70_004289"
     CDS             complement(6795..6977)
                     /locus_tag="IRB70_004289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634130.1"
                     /translation="MRKFKIIIETGIAGGDFEDEFEVDDDATPDEIHDEAKDIFFNYC
                     NYSYHEIKDEEEEQNG"
     gene            complement(7071..7427)
                     /locus_tag="IRB70_004290"
     CDS             complement(7071..7427)
                     /locus_tag="IRB70_004290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001514295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634131.1"
                     /translation="MEIKPEDELSNIVLFPVKEDDPRNQVNFLYEPSERPYCHHASVR
                     VDEKERQVRCKICGAVVEPFDWMLSVAKRETRLADDVRLLRQEERERRKNIEKLIQIE
                     RNAKARIRRATKSRTE"
     gene            complement(7485..7907)
                     /locus_tag="IRB70_004291"
     CDS             complement(7485..7907)
                     /locus_tag="IRB70_004291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HBC0634132.1"
                     /translation="MAKVFTQEEREKIKGQVVELVRQSGRETLRQLETKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKVKKPAVVDPDLIWSSPDG
                     EIRRYDSRLNIICRECRKSEAMQRVLAFYQGNFQEAVL"
     gene            complement(7948..8910)
                     /locus_tag="IRB70_004292"
     CDS             complement(7948..8910)
                     /locus_tag="IRB70_004292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310303.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0634133.1"
                     /translation="MSSKLHGLVWEGCAFTGMILSRVAVMARLADYSNDEGVSWPAIE
                     TIRRQIGARSESTVKSAIAELAKEGWLTKEERKVGGRNVSNIYRLNVEKLEAAAAAAR
                     ESYKPKRKISPAKNDPLTVDPSNIDPSTVDPSNFDGSTVDKKLPIRGAMIDPDPSVLK
                     PDPSDKRSSCPDASQPDPQTAEQDFLTRHPDAVVFSAKKRQWGSQEDLVCAQWIWGRI
                     VSLYEQAASYDGEITRPKEPNWTAWANDVRTMRMLDGRTHRQICEMFGRLQRDSFWVK
                     NIMSPAKLREKWDELVIRLGRSPAQRCVNHISEPDTEIPPGFRG"
     gene            complement(8933..9358)
                     /locus_tag="IRB70_004293"
     CDS             complement(8933..9358)
                     /locus_tag="IRB70_004293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rha family transcriptional regulator"
                     /protein_id="HBC0634134.1"
                     /translation="MKIKHEHIRMAMNAWAYPDGEKVPAAEIARTYFELGMTFPELYD
                     DSHPEALARNTQKIFRWLDKDTPDAVEKIQALLPAIEKAMPPLLVARMRSHSSEYYRE
                     IVERRDRLVKDVDDFVASAVVLYDQMNRGGPAGNAVVMH"
     gene            complement(9342..9665)
                     /locus_tag="IRB70_004294"
     CDS             complement(9342..9665)
                     /locus_tag="IRB70_004294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBC0634135.1"
                     /translation="MKKDNYSFKRACAVVGGQSAMARLLGVSPPSVNQWIKGVRQLPA
                     ERCPAIERATKGGVLCEELRPDVDWTYLRRSSCYSQNMSMKQPNDENDHTRSIKRQMI
                     HENQT"
     gene            9790..10266
                     /locus_tag="IRB70_004295"
     CDS             9790..10266
                     /locus_tag="IRB70_004295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634136.1"
                     /translation="MLSGKDLGRAIEQAINKKIASGAVKSKAEIARHFKVQPPSIHDW
                     IKKGSISKDKLPELWRFFSDVVGPEHWGLNEYPIPTPSTSDTKSELLDINSLYQAASD
                     EKRAIVAFLLSGNATEPSWVDHDVRAYIAAMEMKVANYLKNQESKRKSQNITKTGT"
     gene            10585..10737
                     /locus_tag="IRB70_004296"
     CDS             10585..10737
                     /locus_tag="IRB70_004296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HBC0634137.1"
                     /translation="MDTIDLGNSESLVCGVFPNQDGTFTAMTYTRSKTFKTEAGARRW
                     LTRNTD"
     gene            10749..>10981
                     /locus_tag="IRB70_004297"
     CDS             10749..>10981
                     /locus_tag="IRB70_004297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634138.1"
                     /translation="MEFKDLPVPFQEMASNVVRSQLATLDLSTVEKETIDNISGNVRR
                     AFIGLYEEKQLSDNQDLHEKYFLELMDIINKGFG"
BASE COUNT         2728 a         2902 c         2489 g         2862 t
ORIGIN      
        1 agcagaataa taatggtgcg taattaattc tgcaatctca tccgtttcaa acgattaaat
       61 cctgaacttc cctgactgtc tgctcaaaac gtccggtctc cagttcaacg ccaatcgcac
      121 gacgcccgag cgccagtgca gcttttaccg ttgaacctga gcccataaaa aaatctgcaa
      181 ccaggtcacc cggacgactg cttgcgctga ttatctgctg cagcatttct gccggttttt
      241 cgcacggatg tttcccggga tagaactgca ccggtttatg tgtccacaca tccgtgtacg
      301 gcacctgcgc cgtcacacca aaataccgcc gcagatgctt atattcactc tgcagctcca
      361 catactgccg gttcagtgac gtatacgtat ccaccagctg gtggtggggc ttttccagtt
      421 caccgcgctg atgtttctct tctgccaccc gggcaaacag cgactgtaat ttcagataat
      481 cgctttcgtt cggtagctgc cactgactgg cactgaacca gtgcgacacc atgtttttct
      541 ttcctgtggc atctgcaatc tgttttgccg ttatccccag ggccgcgcgc gcatcacgaa
      601 agtaagaaat cagcggggcc atcacatgct gtttcagtgc actgcccttc gccgcatacc
      661 cggcatcttt cggacgatac ggcccctgat aatgttccgc gaacagaatg cgctctgtgg
      721 cggggaaata cgcccgcagg ctttccttgt tgcatccgtt ccagcgtccg gacggcttcg
      781 cccagataat atggttcagc acactgaagc gttcacgcat catgatttcg atatcagatg
      841 ccaggcgatg accacagaac aggtaaagac ttccgacagg tttcagcacc cgccagaact
      901 gcgccagaca ctggtccagc cacttcaggt aatcatcgtc gcccttccac tggttatccc
      961 agccctcagg cttcacttta aagtacggcg ggtccgtgac tatcaggtca acagaatttt
     1021 cgggtaacga ccggataaat tccaggcagt cggcgttgat taactcacaa ctggatattt
     1081 ttacagtatt aagcatggat cattaagcct gtctctgata ggctcattct gcttttgcgc
     1141 aaagcagtgg gcctgaggtt tgcttgtgaa cccaacgcat gagcagatgg ctggtgggtg
     1201 cccctaacac ccaccagccg cccatttacc acaaataaaa aagccttcac tgcggaaggc
     1261 gtctgtaaca accgaactga tagtctgcca gacccgccat aaccagctga gtcagtatta
     1321 actggcagcg ttcgcgtgaa aggtaagtat tctgcgctat ctccccgact gtcgccggtt
     1381 cggtaacgct taattcatta aacaccactc tggcggtttc tgtcatatcc tgctgtttta
     1441 gcatgtcttt ttcctttttc cggttaacgt gacataccaa taactcttgt cgaaaaagcc
     1501 agcaagctga aagacccgta ttcgcaacca ccagcgtgtt tactgtgctg acgcgatttt
     1561 gggcataaaa aaaaccgcct gacggcagtt ttttttctta ctttgccatc gcgtacaaaa
     1621 tcggcaaaat atcagattta tacgaaacgt acgctattta attgactttt gcaatatctc
     1681 gtcgtgaaaa aatcgctttt tgttgcgctc ttattttcac ggtgcaaatc acagattctc
     1741 tatcgagact cttaaaaata tcgcacatct cacgccagta gttcgcataa ttatggctcc
     1801 agttatcagg cttaactcca cacagtctgg caagctcctg tctctggtag acctcacacc
     1861 cggtaatcca tcctctgaca tcctgtgccg ccagccagat caacttcttc acgcgctcct
     1921 gcgttttccc tgcaattttt ctggtgccgt accgggtttt aaattcattc cacacccact
     1981 gcgttatcgc gatctgatat tcccaacaaa tactcccgct gtaacaccac aacaaccagg
     2041 ctttatgatg ttcttcaaga gacagaacag cccgccgcca cgatgatgtc aaaaactcaa
     2101 ccggactgac gagaggaatt gacgccccct tcgccagcga ttgctttccc gggattggtg
     2161 gattatcccg cgttatcatt tttccagtca cttcatcgcg gtaccggatt tttttacgcc
     2221 tgtaacgccc tgtatcaaac atggcattct cctgccaggc ctcaagctgc ccttttgttg
     2281 atccactcaa atcggcggtg gcaatcatga gttgctcacg aacaaactgt aaatactggt
     2341 tattcatgca tactccagtt ctgtgatttt tatccccaac cgcccaccag gaacaagctg
     2401 accgcgcaca atattaattt catcaaactg ctcgtcgtct atgagcagcc ccgcatgcgt
     2461 cagtacatcc agtggtgcct tcaggatatt gtccaggtca cgacggcgct tatccggtgg
     2521 ctctgcaata atttctattg ccggccttcc ggacaggttt aatttcagtt gctgctggcg
     2581 aacaataagc gccacatcac ggcgataacg ctcaccgact tttgatacaa aatatgtgct
     2641 gccacggcgt cgccagtaag tgttcaccgt cggcgggtaa ggtaaaacca aatctatgag
     2701 catcagtcac ctcttttacc caagcacgcc agttgcaaag gcgtgatcaa gaaaacgaaa
     2761 aattaaatca acctgagaac catgcttttc ttcgaacgcc agaggattcg catgaaactc
     2821 gttgtgatgc tcccgacaca gcggtagcgt gaaaatatcg tgagattttg tccccattcc
     2881 gccctgacca tgaccaatca ggtgatgggg atcgtcggct ggcttaccac aacacgcaca
     2941 cggctgtgtc ttcacccagc gcgtgtattt ctcgttaacc cagcggcgac gtttaggtcg
     3001 tttcatgaag gattccggag actccggatc aacggcaatg ctgaccaccg tcttttcctg
     3061 tggtggattt tgttgctggt ggacgtgaag tggcagcgca atattttttg tgcgctgctt
     3121 cagtatgctg atggctgtct gttctcccgg tacgatgtca ctctcacggt atacggagcg
     3181 gattttttcc gctggtaatc ccagcgaacg acgcgctact gcctcaggta gtgcatccac
     3241 cacctgattg caggccgccc agcaggataa ttcagccagc gataattcac gctcctgtgt
     3301 gccattcatt gcgtgacgaa tgacgtcaat catccatgct gacaggtttt ggtgagcaag
     3361 ttgctcaagt gattcggagg tctggtcacg caactggttg tcgcagtgcc agcacaacac
     3421 cattgcgccg gtaccataac ggtgaatgac ggtttcactg tggtgataat cgccgtgtgg
     3481 ccactggcag gatttaacat ggcgcagtaa ccagtcagac aatgcgccag cgccaccagc
     3541 agcacgaatc actcgttcgt cgctgaaaaa tggcagtaat gatttatcct ccgccagcgg
     3601 ctggcgaacg gcaggaacga ccccggacgg cagattacgc atgcttttcg gttccggctc
     3661 caccagtacc cgggtattgt ggaataccgg catggattca cggcccggct taacgatcac
     3721 cagcccgagt tccggtacca gaacaggtcg aagtaatacc cgcacgttac ctccagatgc
     3781 gttgctggaa tgtgcgggac ggacgcggtg ggcgttcaga gtaaggaagc ctgacggaga
     3841 ttatccagtg acggtagtcg aggctaaggg cttttttaac ctcgtatccg cgcctgcggt
     3901 aacactgaat gagccattcg gcctgttctt cagtgcatgg gggatgctgg taccagtcag
     3961 atttgaatgc gtgaaaacac cgtccgcgcc tgctggcaaa gacggctgaa ttatcagaat
     4021 tgtgtaattt ggtatcgtgc gccatcggtt gtctctgctg gcgcagcagg tgccagttgt
     4081 tcaggctggt gtgcgaattg taaaccagaa tgctaggaaa aaacaaaacc cgccgaagcg
     4141 ggttaagtgc gggtgcgttg aggatgcctg acacatcaga ggtggcgagg gattctcccc
     4201 cgcctggtct cttactcctc aggttcgtaa gctgtgaaga cagcgacctc cgtctggccg
     4261 gttcggattc gtacctcgca gaggtctttc ctcgttacca gtgccgtcac tatgacggtt
     4321 aaacagatga cgatcagggc gattagcatc gccttttgct gcttcatagc ctgcttctcc
     4381 ttgcctttcg gcacgtaaga ggctaaccta cgtgtgtaga gcatagatat ggcctcagat
     4441 taatgttaag cgtcttgcag gacgcgtaat gttaactggg gcttttctct atctgccttt
     4501 tggtgttcat gcctgagaca gatagcctca agcacccgca gtcattctac ttaactaaga
     4561 tttccccgca aaccgttttt gtccggcaca gtaaatatcc aactaaacca atggcgttcg
     4621 ctgtatttac cgccagtatt caatgcacat gaccgccatg aacaccccta aaaaaagggc
     4681 atttatatat ccaaatatta atatcaaaac atcaactttt tccatatacc ttgctgtgaa
     4741 gatgatgggc atacatgata cgaacaacca gaacgcaaca aacaaaaact gcaatgcgtt
     4801 tttcattatt cctcctacaa tcaatgtgca attacattta aacacacctc aatttggccg
     4861 gatatataaa tatctaaacc agaaaaaatc acttacatag cgttacaaac tctttagtct
     4921 aaatattcat cgtaaaacat tccccatact tatcagcccg ttctgcgcca ggtagctcat
     4981 tgccttatct gggaatctgt aatcaggttt ccggatgctg gtggattttc tagactggcc
     5041 ccctgaatct ccagacaacc aatatcactt aaataagtga tagtcttaat actagttttt
     5101 agactagtca ttggagagca gatgattgat gtcttaggac cggagaaacg cagacggcgt
     5161 actacacagg aaaagatcgc tattgttcag cagagttttg aaccgggaat gacggtctcc
     5221 cttgttgccc ggcaacacgg tgtggcagcc agccagttat ttctctggcg caagcaatac
     5281 caggagggaa gtcttactgc tgtggccgca ggagagcagg tcgttcctgc ctctgaactt
     5341 gctgctgcca tgaagcagat taaagaactc cagcgcctgc tcggcaaaaa aacgatggaa
     5401 aatgaactcc ttaaagaagc cgttgaatac gggcgtgcaa aaaagtggat agcgcacgcg
     5461 cccttattgc ccggggatgg ggagtaagct tagtcagccg ttgtctccgg gtgtcgcgtg
     5521 cgcagttgca cgtaattctc agacgaaccg atgactggaa agatggtcgc cgcagccgtc
     5581 actcagatga tacggatgtg cttctccgta tacaccatgt tatcggagag ctgcccacgt
     5641 atggttatcg tcgggtatgg gcgctgcttc gcagacaggc cgaacttgat ggtatgcctg
     5701 cgatcaatgc caaacgtgtt taccggatca tgcgacagaa tgcgctgttg cttgagcgaa
     5761 aaaccgctgt accgccatcg aaacgggcac atactggcaa agtggccgtg aaagaaagca
     5821 atcaacgatg gtgctctgac gggttcgagt tccgctgtga taacggagaa aaactgcgag
     5881 tcacgttcgc gctggactgc tgtgaccgtg aggcactgca ctgggcagtc actacgggcg
     5941 gcttcgacag tgaaacagta caggacgtca tgctgggagc ggtggaacgc cgcttcggca
     6001 acgagcttcc ggcgtctcca gtagagtggc tgacggataa tggttcatgc taccgggcta
     6061 atgaaacacg gcagtttgcc cggatgttgg ggcttgaacc gaagaacacg gcggtgcgga
     6121 gtccggagag taacggcata gcagagagct tcgtgaaaac gataaagcgt gactacatca
     6181 gtatcatgcc taaaccagac gggttaacgg cagcaaagaa ccttgcagag gcgttcgagc
     6241 attataacga atggcatccg catagtgcac tgggttatcg ctcgccacgg gaatatctgc
     6301 ggcagcaggc cagtaatggg ttaagtgata acaggtgtct ggaaatatag gggcaaatcc
     6361 attttcgcgt tttagttgtt cataaaagtg cacagcttta accagttctt ctgatgtaac
     6421 cgggactggc ggggcagtga ataaggcctg aatttcatag ttcggcctgt cgttacaatc
     6481 ctcttttttc ggtacatatt tccagtcacc agaccactac ttcccctgaa agtccgtaac
     6541 gccttttttt tcacgtagcg atatcgccat gccactgttt ttgcttgccc cgccgtttca
     6601 tgcccttcct gataattaac ctcgctcatt catcgcccca ctcatcacaa tatgcttcga
     6661 ccggagtttt tcctgcttca taatcatcac gccatgcttc agcatcagca gcactgccac
     6721 cacgtaactc tgcatagtcc attaacagtt catgccattc ttcaaaactg acgttgtatt
     6781 tagttgaacc aaaatcagcc attttgttct tcctcttcgt cttttatttc gtgatatgag
     6841 taattgcagt agttaaagaa aatatctttt gcttcgtcat gtatttcatc aggcgtcgca
     6901 tcatcatcca cttcgaattc atcctcgaaa tctccaccgg ctattcccgt ttcaataatt
     6961 attttaaact ttcgcattta actaccgccc tttcgggcgg cctcctgatg ttctgagggt
     7021 gcagaaatcc ctccggttaa ggattaaatt tttaacagag ctaaatttaa ttattcagtt
     7081 ctggattttg tcgccctgcg tatccgcgct ttcgcgttac gctcaatctg aattagcttt
     7141 tctatatttt ttcgcctttc ccgctcctct tgacgcaaga gccttacatc atctgccagt
     7201 ctggtttctc ttttcgccac agagagcatc cagtcaaatg gctccacaac tgcaccgcag
     7261 attttacagc ggacctgacg ctctttttcg tcaacccgga cagaggcgtg atgacaatat
     7321 ggtctttccg atggctcata aagaaaatta acctgattac gagggtcatc ctcttttacc
     7381 ggaaataaaa cgatattgct taactcatcc tctggtttta tttccatgct cctctccttt
     7441 gatgcgaatg ccagcggtaa ttgaagcctg atagctaatt tcactcacag taccgcctcc
     7501 tgaaaattac cctgatagaa agccagtaca cgctgcatag cttcactctt ccggcactcg
     7561 cgacagatta tgtttaggcg actgtcgtag cgacgtattt ctccgtcagg tgatgaccag
     7621 ataaggtccg gatcaaccac agcaggtttc ttcacctttg ccctcgagag ttttttgcgg
     7681 gcgttttgcc agtccttacg cgcctgttca gaggggaata acccgtagcc ggagttgtat
     7741 acatcgccgc tggcaaccag ctctctggcc agaacgctca tcagatatct tgttgcccca
     7801 gttttagttt ccagttgtcg taacgtctcg cgcccactct ggcgtacgag ttcaacaacc
     7861 tgccctttaa ttttttcccg ctcttcttgt gtaaaaactt ttgccacaag ccctcctgaa
     7921 aattacctca tgaccagaaa ttaacactta ccccctgaag cccggcggaa tttcagtgtc
     7981 cggttcagaa atgtgattca cgcaacgctg cgcaggcgaa cgccccaggc ggataaccag
     8041 ttcatcccat ttttcccgga gttttgccgg actcatgatg ttttttaccc agaacgaatc
     8101 ccgctggaga cgcccaaaca tttcacaaat ttgtctgtga gttctgccat ccagcatccg
     8161 cattgtgcga acgtcattgg cccatgctgt ccagttgggt tctttcggtc tagtgatctc
     8221 gccatcatag ctggccgcct gctcgtaaag actcacgatt cgtccccaga tccactgtgc
     8281 gcacaccaaa tcttcctgac ttccccactg gcgttttttc gcactgaaca caaccgcgtc
     8341 agggtgtcgg gttaaaaaat cctgttcagc cgtctgcggg tccggttgcg aagcgtccgg
     8401 acaagaagat cttttatctg acggatcagg ttttaatact gacggatcgg ggtcaatcat
     8461 cgccccccta atcggcagtt ttttatcaac agttgatcca tcaaaatttg acgggtcaac
     8521 cgttgagggg tcaatatttg acgggtcaac tgttaacggg tcattttttg ccgggctaat
     8581 ttttcttttc ggtttatatg actcacgcgc cgccgccgca gctgcttcga gtttttccac
     8641 attaagtcga tagatattgc ttacattacg cccaccgacc ttacgctctt ccttcgtcag
     8701 ccagccctct ttcgccagtt ctgcaatagc cgatttcact gtggattcac ttcttgcacc
     8761 gatctgacgc cggatagttt caatggcagg ccatgacacg ccctcgtcat tgctgtagtc
     8821 tgcaagacgg gccataaccg ccaccctgga taagatcatg ccggtgaagg cgcacccttc
     8881 ccagacaaga ccatgaagct tgctgctcat aaaacccccg aacaccgtgc ttttagtgca
     8941 tcaccacagc attccctgcc gggccgccgc gattcatctg gtcatacaaa acaaccgctg
     9001 acgcaacaaa atcgtcgaca tccttcacca gccgatcccg ccgttcgaca atctcccggt
     9061 aatactcaga gctgtgactg cgcatacggg ccaccagcag aggcggcatt gccttttcga
     9121 tcgccggtaa cagagcctga attttttcaa cagcatcagg ggtgtcttta tccagccaac
     9181 ggaaaatttt ctgtgtatta cgggccaggg cttccggatg gctgtcgtcg tacagttcag
     9241 ggaacgtcat ccccagttcg aaataagtcc gggctatttc agctgcagga actttctcac
     9301 catcagggta tgcccaagca ttcatcgcca tgcggatgtg ctcatgtttg attttcatga
     9361 atcatttgcc tcttgatgct tcgggtatga tcgttttcgt catttggttg cttcatcgac
     9421 atattctgcg aataacatga cgagcgtcgt aagtatgtcc aatcaacatc aggacgaagt
     9481 tcttcacaca ggacaccacc ttttgttgct cgttcaatcg caggacatct ctcagcaggc
     9541 aactgacgta cacctttgat ccattgattt acgcttggag gagatacacc taaaagccta
     9601 gccattgctg attgcccacc gacaacagca caagctcgtt tgaatgaata gttatctttt
     9661 ttcatcgaat gaactccaaa aaacacgcaa caatattagg cttagcctaa tgcaattgtc
     9721 aataggctat gcctaataca tcgagagtag ggattgccta acgcgatgcg cataggagac
     9781 tattaagcaa tgcttagtgg taaagactta ggccgagcga ttgagcaggc cattaacaaa
     9841 aaaattgcat caggagccgt caaatcaaag gcggaaatcg cacgtcattt caaagtccaa
     9901 ccaccatcaa tccatgactg gattaagaaa ggttcgataa gtaaagacaa acttccagaa
     9961 ctatggcgtt tcttttctga tgtggttggt ccagagcatt gggggcttaa cgaatacccc
    10021 ataccaaccc catccacttc agatacaaaa agtgaacttt tagacataaa cagcctttat
    10081 caagccgcct ctgatgaaaa aagagcaatt gtggctttcc tcttatctgg aaatgctacg
    10141 gagcctagtt gggttgatca tgacgttcgc gcctacattg ccgcaatgga aatgaaggta
    10201 gctaactatc tgaaaaatca agaatcaaaa cggaaaagcc agaacatcac caagacagga
    10261 acttaaactt atatggtccg acgggaaatt cctagttccc gttagttaac tcctactacc
    10321 tctcccacaa accatcacct attaggtcgc gcccaaatta ttaggcatag cctattgaca
    10381 agtaattagg catttcctat agttttccca taccaaccca tcccgtccca cacaatacag
    10441 ggcaatacct cgagttacca ggcagtggtc aggggttaag tagccagccc gatgcgtaag
    10501 aacatgacgg cagggttcaa ctttaataac tatgcagcag gtttttgttc cgctaccccg
    10561 gcgttaaggg gaaatgaggt cagcatggat actatcgatc ttggcaacag cgaatctctg
    10621 gtatgtggcg tgttccccaa ccaggacggt acgtttaccg cgatgacgta taccagaagc
    10681 aaaacgttta aaactgaagc tggcgcgcgt cgctggttaa ccagaaacac tgactgatga
    10741 ggttgacgat ggaatttaaa gatttaccag taccattcca ggaaatggca tcgaatgtgg
    10801 ttcgctctca actggcgact cttgacctga gtaccgtaga aaaagaaacc atcgacaata
    10861 tatccggtaa cgtacgccga gcctttatcg ggctgtacga agagaagcag ctctctgata
    10921 accaggattt acatgaaaaa tactttctgg aattaatgga catcattaat aaaggatttg
    10981 g
//
LOCUS       DADXDL010000123        10706 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.123, whole genome shotgun sequence.
ACCESSION   DADXDL010000123 DADXDL010000000
VERSION     DADXDL010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10706)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10706)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10706
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.123"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..546)
                     /locus_tag="IRB70_004298"
     CDS             complement(<1..546)
                     /locus_tag="IRB70_004298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LptF/LptG family permease"
                     /protein_id="HBC0634139.1"
                     /translation="MKLVEHYIMRGTRRLVLIIVGFLIFIFASYSAQRYLTEAANGTL
                     ALDVVLDIVFYKVLIALEMLLPVGLYASVGVTLGQMYTDSEITAISAAGGSPGRLYKA
                     VLYLAIPLSIFVTLLSMYGRPWAYAQIYQLEQQSQSELDVRQLRAKKFNTNDNGRMIL
                     SQTVDQDNNRLTDALIYTSTAN"
     gene            complement(577..1137)
                     /locus_tag="IRB70_004299"
     CDS             complement(577..1137)
                     /locus_tag="IRB70_004299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708799.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtfJ family protein"
                     /protein_id="HBC0634140.1"
                     /translation="MPSRWIFALIIALLAPGAVAHNFVTGKTVTPVYIQEGGELLLNS
                     DDEIHYQKWNSTQLAGKVRIIQYIAGRKSAKKKNSLLIKAVEAANFPQDRFQPTTIVN
                     TDDAIFGTDYFVVGKIEKNKRRYPWAQFVIDGNGQGRVAWRLPEQSSTILVLNKNGQI
                     QWAKDGSLTPEEVDHVIALAQKLINE"
     gene            complement(1137..1973)
                     /locus_tag="IRB70_004300"
     CDS             complement(1137..1973)
                     /locus_tag="IRB70_004300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000984967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634141.1"
                     /translation="MMRKYFPLEASERLFVAIEEDDVVDAQVSLPPTIALSCTTEIIH
                     DNYALCLKFWLDGVNRQELLRLIRKQAKGDELTTDERKKYKYMRARYKHLRFAQRLYL
                     KKHQAGFLFGKTTVFLGRFQDGFRNGKKNIVSYYGNLLRVYLSSPVWSLVNYSLRHSQ
                     LESVSGFIAYRQKQMHTLKEIIAKPRLTGREFHDVRKIISQQVSYYDTLRSLDPENKE
                     ALQISRFLAAINGLMGDKHDDMVADDMENRQSYDAPMALDSDIRQRLELLISRFPLYP
                     EQ"
     gene            complement(1973..3322)
                     /locus_tag="IRB70_004301"
     CDS             complement(1973..3322)
                     /locus_tag="IRB70_004301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide biosynthesis protein"
                     /protein_id="HBC0634142.1"
                     /translation="MAGFNIKHWFADGAFRTIIRNSAWLGSSNVVSALLGLLALSCAG
                     KGMTPAMFGVLVIVQSYAKSISDFIKFQTWQLVVQYGTPALTNNNPQQFRNVVSFSFS
                     LDIVSGAVAIVGGIALLPFLSHSLGLDDQSFWLAALYCTLIPSMASSTPTGILRAVDS
                     FDLIAVQQATKPFLRAAGSVVAWYFDFGFAGFVIAWYASNLVGGTMYWWFAARELRRR
                     NIHNAFKLNLFESARHIKGAWSFVWSTNIAHSIWSARNSCSTVLVGIVLGPAAAGLFK
                     IAMTFFDAAGTPAGLLGKSFYPEVMRLDPRTTRPWLLGVKSGLLAGGIGILVALAVLI
                     VGKPLISLVFGVKYLEAYDLIQVMLGAIVISMLGFPQESLLLMAGKQRAFLVAQTIAS
                     IGYIVLLFMFCHLFGVLGAAFAYFAGQCLDVVLSLIPTLKAFFQRHSLLYNAAGEKS"
     gene            complement(3368..4126)
                     /locus_tag="IRB70_004302"
     CDS             complement(3368..4126)
                     /locus_tag="IRB70_004302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634143.1"
                     /translation="MDALQTQTVNSTTVPQPNYIPGLIAVVGCDGTGKSTLTTDLVKS
                     LQQHWQTERRYLGLLSGEDGDKIKRLPLVGVWLERRLAAKSSKTQSMKTKSPALWAAV
                     IMYCFSLRRMANLRKVQRLAQSGVLVVSDRFPQAEISGFYYDGPGIGVERATGKINQF
                     LAQRERQLYQQMAQYRPELIIRLGIDIDTAISRKPDHDYAELQDKIGVMSTIGYNGTK
                     ILEIDSRAPYSEVLEQAQKAVSLVAIVSDRRSLT"
     gene            complement(4158..4871)
                     /locus_tag="IRB70_004303"
     CDS             complement(4158..4871)
                     /locus_tag="IRB70_004303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBC0634144.1"
                     /translation="MNQRNMSIINSTPVRVIAIVGCDGSGKSTLTASLVNELAARMPT
                     EHIYLGQSSGRIGEWISQLPVIGAPFGRYLRSKAAHVHEKPLTPPGNITALVIYLLSC
                     WRAYKFRKMLCKSQQGYLLITDRYPQVEVPGFRFDGPQLAKTTGGNGWIKMLRQRELK
                     LYQWMASYLPVLLIRLGIDEQTAFSRKPDHQLAALQEKIAVTPQLTFNGAGILELDGR
                     QPADEIMQASLRAIHAALS"
     gene            5045..5737
                     /locus_tag="IRB70_004304"
     CDS             5045..5737
                     /locus_tag="IRB70_004304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate kinase"
                     /protein_id="HBC0634145.1"
                     /translation="MQSITPPLIAVIGSDGSGKSTVCEHLITVVEKYGAAERVHLGKQ
                     AGNVGRAVTKLPLMGKSLHKTIERNQVKTAKKLPGPVPALVITAFVARRLLRFRHMLA
                     CRRRGLIVLTDRYPQDQIPGAYDGTVFPPNVEGGRFVSWLASQERKAFHWMASHKPDL
                     VIKLNVDLEVACARKPDHKRESLARKIAITPQLTFGGAQLVDIDANQPLEKVLVDAEK
                     AITDFMTARGYH"
     gene            complement(5786..7285)
                     /gene="pitB"
                     /locus_tag="IRB70_004305"
     CDS             complement(5786..7285)
                     /gene="pitB"
                     /locus_tag="IRB70_004305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inorganic phosphate transporter PitB"
                     /protein_id="HBC0634146.1"
                     /translation="MLNLFVGLDIYTGLLLLLALAFVLFYEAINGFHDTANAVATVIY
                     TRAMQPQLAVVMAAFFNFFGVLLGGLSVAYAIVHMLPTDLLLNMGSTHGLAMVFSMLL
                     AAIIWNLGTWFFGLPASSSHTLIGAIIGIGLTNALLTGSSVMDALNLREVTKIFSSLI
                     VSPIVGLVIAGGLIFLLRRFWSGTKKRDRIHRIPEDRKKKKGKRKPPFWTRIALIVSA
                     AGVAFSHGANDGQKGIGLVMLVLVGIAPAGFVVNMNASGYEITRTRDAVTNFEHYLQQ
                     HPELPQKLIAMEPPLPAASTDGTQATEFHCHPANTFDAIARVKTMLPGNMESYEPLSV
                     SQRSQLRRIMLCISDTSAKLAKLPGVSKEDQNLLKKLRSDMLSTIEYAPVWIIMAVAL
                     ALGIGTMIGWRRVAMTIGEKIGKRGMTYAQGMAAQMTAAVSIGLASYIGMPVSTTHVL
                     SSAVAGTMVVDGGGLQRKTVTSILMAWVFTLPAAIFLSGGLYWIALQLI"
     gene            complement(7577..9436)
                     /gene="gss"
                     /locus_tag="IRB70_004306"
     CDS             complement(7577..9436)
                     /gene="gss"
                     /locus_tag="IRB70_004306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutathionylspermidine
                     amidase/synthase"
                     /protein_id="HBC0634147.1"
                     /translation="MSKGTTSQDAPFGTLLGYAPGGVAIYSSDYSSLDPQEYEDDAVF
                     RSYIDDEYMGHKWQCVEFARRFLFLNYGVVFTDVGMAWEIFSLRFLREVVNDNILPLQ
                     AFPNGSPRAPVAGALLIWDKGGEFKDTGHVAIITQLHGNKVRIAEQNVIHSPLPQGQQ
                     WTRELEMVVENGCYTLKDTFDDTTILGWMIQTEDTEYSLPQPEIAGELLKISGARLEN
                     KGQFDGKWLDEKDPLQNAYVQANGQVINQDPYHYYTITESAEQELIKATNELHLMYLH
                     ATDKVLKDDNLLALFDIPKILWPRLRLSWQRRRHHMITGRMDFCMDERGLKVYEYNAD
                     SASCHTEAGLILERWAEQGYKGNGFNPAEGLINELAGAWKHSRARPFVHIMQDKDIEE
                     NYHAQFMEQALHQAGFETRILRGLDELGWDAAGQLIDGEGRLVNCVWKTWAWETAFDQ
                     IREVSDREFAAVPIRTGHPQNEVRLIDVLLRPEVLVFEPLWTVIPGNKAILPILWSLF
                     PHHRYLLDTDFTVNDELVKTGYAVKPIAGRCGSNIDLVSHHEEVLDKTSGKFAEQKNI
                     YQQLWCLPKVDGKYIQVCTFTVGGNYGGTCLRGDESLVIKKESDIEPLIVVKE"
     gene            9641..10507
                     /gene="yghU"
                     /locus_tag="IRB70_004307"
     CDS             9641..10507
                     /gene="yghU"
                     /locus_tag="IRB70_004307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311901.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-dependent disulfide-bond
                     oxidoreductase"
                     /protein_id="HBC0634148.1"
                     /translation="MTDNTYQPAKVWTWDKSAGGAFANINRPVSGPTHEKTLPVGKHP
                     LQLYSLGTPNGQKVTIMLEELLALGVTGAEYDAWLIRIGDGDQFSSGFVEVNPNSKIP
                     ALRDHTHTPPIRVFESGSILLYLAEKFGYFLPQDLAKRTETLNWLFWLQGAAPFLGGG
                     FGHFYHYAPVKIEYAINRFTMEAKRLLDVLDKQLAQHKFVAGDEYTIADMAIWPWFGN
                     VVLGGVYDAAEFLDAGSYKHVQRWAKEVGERPAVKRGRIVNRTNGPLNEQLHERHDAS
                     DFETNTEDKRQG"
BASE COUNT         2756 a         2801 c         2590 g         2559 t
ORIGIN      
        1 attggcagta gaagtataaa tcagcgcgtc agtcaggcga ttattatcct gatcaaccgt
       61 ctgcgaaagg atcattcgtc cgttatcgtt agtgttaaat ttctttgccc gcaactggcg
      121 aacatccagc tccgactgtg actgttgctc cagttgataa atctgcgcat aagcccacgg
      181 acgaccatac atcgacagaa gggtgacaaa aatacttagc ggtatcgcca gataaagaac
      241 ggctttgtac aagcgtcccg gactgccccc cgccgcggag atagcggtaa tttccgagtc
      301 ggtatacatt tgccctagcg tcacgccaac tgaagcatat agtccaacag gtaacagcat
      361 ctccagtgca atcagcactt tgtagaaaac gatatccagc acaacatcaa gagctaatgt
      421 cccatttgcc gcttcggtca gataacgctg tgcggagtag ctggcgaaaa taaagatcag
      481 aaaaccgacg ataatcagca ccagacggcg cgtaccacgc atgatgtagt gttcaaccag
      541 cttcatctca ctaacgccct caatcctttg agttttttat tcattgatca gcttctgcgc
      601 cagcgcaatg acatgatcta cctcttccgg cgtcaggctg ccgtcctttg cccactgaat
      661 ttgcccgttt ttattcagca ccagaatggt tgaactctgc tccggcaagc gccaggcaac
      721 acgtccctgt ccattgccgt caataacgaa ttgcgcccat ggatagcggc gtttattttt
      781 ttcgattttg ccaacgacaa aatagtcggt accaaagatg gcatcatcgg tgttcacaat
      841 ggtggtgggc tgaaaacgat cctgcggaaa gtttgccgct tcaaccgctt taattaacag
      901 tgagttcttt ttcttcgccg acttacgccc ggcgatatac tgaataatgc ggacttttcc
      961 cgccagctgt gtgctgttcc acttttggta gtgaatttcg tcgtcgctat tcagaagcaa
     1021 ctcaccgcct tcctggatat aaacaggggt aaccgtttta ccagtgacga aattgtgtgc
     1081 caccgcgcct ggcgctaaga gtgcgatgat cagagcgaaa atccaacgag atggcattat
     1141 tgctccggat agagtgggaa acgcgaaatc agcagttcta agcgctgacg aatatcgcta
     1201 tccagcgcca tcggtgcatc atacgactgg cggttttcca tatcatccgc caccatgtcg
     1261 tcgtgtttat cccccatcag gccattaatg gcggcgagga agcgggaaat ctgtaacgcc
     1321 tctttatttt caggatcaag cgatcttagg gtgtcgtaat aagaaacctg ctggctgatg
     1381 atttttcgca catcatgaaa ttccctgcca gttagtcgcg gtttggcaat tatctctttc
     1441 agggtatgca tttgcttttg ccgataggca ataaaaccgc ttacgctttc taactggcta
     1501 tggcgtaatg aatagttcac caacgaccag accggagagc ttaaataaac ccgtaacagg
     1561 ttgccgtaat acgacacaat atttttctta ccgttacgaa agccgtcctg aaaacgcccc
     1621 aaaaaaacgg tcgttttgcc gaataaaaat ccggcctgat gcttctttaa atacagccgt
     1681 tgcgcaaagc gcagatgctt gtagcgcgct cgcatgtatt tatacttttt gcgctcgtct
     1741 gtcgtcagct catcgccttt cgcctgtttg cggattaaac gcagtagctc ctgacgatta
     1801 acaccatcca gccagaattt caggcataac gcgtaattat catggatgat ttcggtggta
     1861 caacttagtg cgatagtcgg cggcaaactg acctgtgcat caacgacatc atcttcttca
     1921 atcgcaacaa atagacgctc gctagcctca agcgggaaat attttctcat catcaggatt
     1981 tctctccggc tgcgttataa agcaaggaat ggcgctgaaa aaatgccttt aaggttggaa
     2041 ttagcgagag caccacatcc agacattgcc cagcgaagta agcaaatgca gcccccagca
     2101 cgccaaacag atgacagaac atgaacagca atacgatgta gccgattgag gcgatggttt
     2161 gcgccacgag aaaagcacgc tgttttcccg ccatcaatag caatgactcc tgtgggaagc
     2221 ccagcatcga aatcacaatt gcgcccagca tcacctgaat caggtcatac gcttcgagat
     2281 acttaacgcc aaacaccagc gaaatgagcg gcttgccgac gatcaacacc gcgagcgcca
     2341 ccagaatacc gattccgccc gccagtaaac cggacttcac gcctaacaac cacggtctgg
     2401 tggtgcgcgg atctaaacgc atcacctctg ggtaaaaact tttacctagt aaacccgctg
     2461 gcgttccggc ggcgtcgaag aatgtcatgg cgattttaaa taacccggcg gcagcgggtc
     2521 ctaacacgat ccccaccaac actgtgctgc acgaattacg cgccgaccag atggaatggg
     2581 caatgttggt tgaccagaca aaactccacg cgcctttgat gtgtcgggca gactcaaaca
     2641 gattcaattt gaacgcgtta tggatatttc tgcggcgtaa ttcacgtgcg gcaaaccacc
     2701 agtacatggt gccgccaaca agattcgagg cgtaccaggc aataacaaaa cccgcaaaac
     2761 caaagtcaaa ataccaggca acgacgctcc ccgctgcgcg cagaaaaggt ttcgtcgcct
     2821 gctgtacagc aattaagtcg aagctatcta ccgcacgcag aatgccggtc ggcgtggagg
     2881 aagccattga aggaatgagc gtgcaataca gcgctgccag ccaaaagctt tggtcatcca
     2941 gacctaatga atgggaaaga aaagggagta aggcaatgcc gccgacaatc gccaccgcgc
     3001 cgctgacgat atccaacgag aaggaaaatg agacgacatt gcgaaattgc tgcggattat
     3061 tgttggtcaa ggctggcgtt ccgtactgca ccaccaactg ccatgtctga aacttaataa
     3121 aatcgctgat cgacttggcg tacgattgca caatcaccag tacgccaaac atggcgggcg
     3181 tcatcccttt accggcacac gagagcgcca acagacccag caaagcgctc acgacattac
     3241 tggagcctaa ccaggcgcta ttgcgaataa tggtgcgaaa cgcgccatct gcaaaccaat
     3301 gtttgatgtt aaaacccgcc aattcagcct gaccttatcg ttgatagtaa aaagtatccc
     3361 gccagcctta agttaaactt cggcggtcag aaacgatggc aaccagagaa accgccttct
     3421 gtgcctgttc cagcacttcg ctgtagggcg ctctggaatc aatctcaaga atttttgtgc
     3481 cgttatagcc aatcgtcgac atgacgccga ttttgtcctg cagctcggca tagtcatggt
     3541 caggcttgcg ggagatggca gtatcaatat caatccccaa acgaatgatt aattcaggac
     3601 gatactgcgc catttgttgg tataactgtc gctcgcgctg cgccagaaat tggttgattt
     3661 tcccggtcgc gcgctcgacg ccaatccccg gtccgtcata ataaaagccc gaaatttcag
     3721 cctgcgggaa gcgatcgctg accaccagaa cgccactttg cgccagtcgc tgaaccttgc
     3781 gtagattcgc cattcttcgc agcgagaagc agtacataat caccgccgcc catagcgctg
     3841 gagatttggt tttcatgctt tgggttttcg aggatttggc cgccagtcgc cgttccagcc
     3901 agacgccaac caacggcaat cgtttgattt tgtcgccgtc ttcgccggag agcagcccca
     3961 aatagcggcg ctcggtttgc cagtgttgtt gcagcgattt caccaggtcg gtggtcagcg
     4021 tggatttacc ggtgccatca cacccgacca ccgcaatcag ccccggaatg tagttgggct
     4081 gcggcacggt tgtactatta acagtttgtg tttgtagtgc atccattcgt taaatcatcc
     4141 cctatccatt ttggtgatca ggaaagcgcg gcgtgaattg cgcgtagtga cgcttgcata
     4201 atttcatcgg ctggttgccg accatccagt tcaaggatcc cggcgccatt gaatgtcagt
     4261 tgcggcgtaa cggcgatttt ttcctgtaac gccgccagtt gatggtcagg tttacgcgaa
     4321 aacgcggttt gttcatcaat gccaagacga atcaacaata cgggcaaata agacgccatc
     4381 cattggtaca gcttcagctc gcgctgcctt aacattttta tccagccgtt accgcccgtg
     4441 gtttttgcca attgcgggcc atcaaagcga aaacccggca cttcaacctg cgggtagcgg
     4501 tcggtgatga gcagatagcc ttgctggctt ttacacaaca ttttgcgaaa cttgtacgcc
     4561 cgccagcagg aaagcagata gataaccagc gcagtaatat tgccaggcgg tgttaagggc
     4621 ttttcgtgca catgtgccgc tttacttcgc aaataacgcc caaaaggtgc gccaataaca
     4681 gggagctgtg aaatccattc gccaattcgc ccggacgatt gcccgagata aatgtgttct
     4741 gttggcattc ttgctgccag ttcatttacc aggcttgccg tgagggtcga tttacctgaa
     4801 ccatcacatc ctacaatggc aataacacgc actggcgtgg aattaattat tgacatatta
     4861 cgttgattca cgaaaaaccc ggcagcaaat aatgtattga atattacgtg gtccgtgctc
     4921 agaatatccg ttcaacctta ttgtgacaat ggttaattgt gacattgacc tgaattacgc
     4981 tttcataaaa acatattaac caaataaata tttttaatgg atatttaaat taaaggatat
     5041 attcatgcag tcaataacac ctccattaat tgccgttatt ggtagcgatg gttcaggcaa
     5101 gtcaacggtg tgtgaacatc tcattaccgt tgtcgaaaaa tatggtgctg ccgaaagagt
     5161 tcatttagga aaacaggccg gaaatgtcgg tcgtgcagtg acaaaattac cgttgatggg
     5221 aaaatcctta cataaaacaa ttgaacgaaa tcaggtgaaa acagcaaaaa aattgcctgg
     5281 gccagttccg gcgctggtaa ttacagcgtt tgtcgcccgt cgcttactgc gctttcgtca
     5341 tatgcttgcc tgtcgtcgtc gcgggttaat tgttctaacc gaccgttatc ctcaggacca
     5401 aattcctggc gcttacgatg gtacagtgtt cccgcctaac gttgaaggcg gccggtttgt
     5461 ctcatggctg gcaagccagg aacgtaaagc gtttcactgg atggcgagcc ataaacctga
     5521 tctggtcatc aaactcaatg ttgaccttga agttgcctgc gcgcgtaaac ccgaccataa
     5581 acgggaatcg ctggcgagga agattgccat aacgccacag ttaacctttg gcggtgcaca
     5641 actggttgat atcgatgcta atcagccact ggaaaaggtg ctggttgatg cagaaaaagc
     5701 gattacggat tttatgaccg cgcgtggtta tcactagtca aaaatggaaa tgcccgatcg
     5761 ccaggaccgg gcattttcag gaaggttaaa tcaactgcaa tgctatccag tacaacccac
     5821 cagaaagaaa aatcgccgcc ggtaaagtaa atacccacgc catcaggatg ctggttaccg
     5881 ttttacgctg taacccaccg ccgtccacca ccatcgtccc tgctacggca gatgagagta
     5941 cgtgtgttgt ggagacgggc atcccaatat aactggcaag gccgatagac actgccgccg
     6001 tcatttgtgc cgccatgcct tgcgcatacg tcatgccgcg cttaccaatc ttctcaccga
     6061 tggtcatcgc tacacgacgc cagccaatca tggtgccaat gccgagcgcc agagctactg
     6121 ccatgatgat ccacaccgga gcgtactcaa tggtgcttaa catatcgctg cgcagttttt
     6181 tcagcaggtt ctggtcttct ttactgacgc ctggcagttt cgccagcttc gcggaggtat
     6241 cagagatgca cagcataatg cggcgcagct ggctgcgctg actcacgctt aacggctcgt
     6301 aactttccat attgcctggc agcatcgttt taacgcgcgc aatcgcatca aaggtatttg
     6361 ccggatgaca gtgaaactcc gtcgcttgcg tgccatcagt cgatgccgca ggcaatggcg
     6421 gttccatcgc gatcaacttc tgcggcagtt caggatgctg ttgcagatag tgttcgaagt
     6481 tagtcactgc atcgcgggta cgggtaattt catagccaga cgcattcata ttgacgacga
     6541 aaccagcagg ggcaatcccc accagtacca gcatcaccag accgatccct ttctgcccgt
     6601 cattcgcacc gtgcgaaaat gccacgcccg cagcggaaac aatgagggca atacgcgtcc
     6661 agaatggcgg cttacgtttg ccctttttct ttttgcgatc ttcaggaata cggtgaatgc
     6721 ggtcacgctt tttcgtcccg ctccagaaac ggcgcagcag gaaaatcagt cctcctgcaa
     6781 tgaccaggcc gacgatgggg gagacaatca gcgaggagaa aatcttggtc acttcacgca
     6841 ggtttaacgc atccatcacc gatgagccgg ttaacagcgc gttggttaaa ccgatgccga
     6901 taatcgcgcc aatcaaggtg tgcgaactgg aagcaggtaa accaaagaac cacgttccca
     6961 ggttccagat aatcgccgcc agcagcatgg aaaagaccat cgccagaccg tgggttgacc
     7021 ccatattcaa tagcaaatcg gttggtaaca tatggacaat ggcataggca acgctaagtc
     7081 cgcctagcaa tacgccaaaa aagttaaaaa atgccgccat caccacagca agttgtggtt
     7141 gcatggcacg agtataaata acggttgcca ccgcattcgc cgtgtcatga aaaccattga
     7201 ttgcttcgta gaacaacaca aatgccagag caagtaataa caaaagccct gtgtatatat
     7261 caaggccaac aaataaattt agcatatatt agattacgcc attttgaatt tacgaacgga
     7321 cgcattatca gtgactttaa cggcgtgggc aaagtgaaat atcatttttt aacgataaaa
     7381 agagtgttat ttcttgtgta tcagataata agcattcatt caaaaccttt agaaataatc
     7441 aaaacacagg cattccactg gttaatacat tcacacatga aatgaataaa tatttgaata
     7501 tataaatatt gaatattttg attaatcccc gcactgatta ttcttcataa tcagtgcggg
     7561 gttgctacaa catgtattac tctttcacca caattaacgg ttcaatatca ctctcttttt
     7621 taatgaccag tgattcatca ccgcgcaaac acgtcccacc gtagttgccg ccaacggtga
     7681 aggtacatac ctgaatgtat ttaccgtcca ctttcggcaa acaccacagt tgctgataga
     7741 tgtttttctg ctcggcaaat ttaccgctgg ttttgtccag cacctcttca tgatggctga
     7801 cgaggtcgat gttactgcca cagcgaccgg cgatcggttt cactgcgtaa cctgttttta
     7861 ccagttcatc attaacagtg aaatcggtat ccagcaggta acgatggtgc gggaacagag
     7921 accagaggat cggcagaatc gctttgttgc cggggatcac tgtccacaga ggttcaaaga
     7981 ccagcacttc cgggcgcagc aatacgtcga taagacgcac ttcattttgc ggatgaccgg
     8041 tacggatcgg caccgcagca aactcacggt cgctaacttc acgaatctga tcaaacgcgg
     8101 tttcccacgc ccaggttttc cacacgcagt taaccagtcg cccttcccca tcaatcagtt
     8161 gcccggcagc atcccagccc agttcatcca gcccgcgcaa gatacgcgtt tcaaagcccg
     8221 cctggtgcag cgcctgctcc ataaactgcg cgtgatagtt ttcctcgata tctttgtcct
     8281 gcatgatatg gacaaacgga cgtgcacgac tgtgtttcca ggcaccagcc agttcgttaa
     8341 tcagcccttc cgccggattg aagccgttgc ctttatagcc ctgctccgcc caacgttcga
     8401 ggatcaagcc cgcttcggta tgacaggagg cggaatcggc gttgtattcg tagaccttca
     8461 ggccacgttc gtccatacag aaatccatac gaccggtgat catatggtga cggcgacgct
     8521 gccaggagag acgcaaacgt ggccagagga ttttcggaat gtcgaacagc gccagcaggt
     8581 tgtcatcttt cagcaccttg tcggtggcgt gaagatacat caggtgcagt tcgttggtgg
     8641 ctttaatcag ctcctgctcg gcactctcgg taatggtgta gtaatgatac ggatcctgat
     8701 tgatcacctg accgttggcc tgcacatagg cgttttgtag cggatctttt tcatccagcc
     8761 atttaccgtc aaactgacct ttgttttcca ggcgcgctcc gctgattttc agcagctcgc
     8821 ctgcaatttc cggctgcggt aagctgtatt cagtatcttc cgtctggatc atccagccca
     8881 gaatggtggt gtcatcaaac gtgtctttaa gggtatagca gccgttttcg accaccatct
     8941 ccagctcgcg tgtccactgt tgcccttgcg gtaacgggga atgaatcacg ttctgttccg
     9001 caatacggac tttgttgcca tgcaattggg taatgatggc gacatggcca gtgtctttaa
     9061 attcaccgcc tttatcccag ataagaagcg cgcccgcgac cggtgcacgc ggcgagccat
     9121 taggaaatgc ctgcaatggc aggatgttgt cattaaccac ttcacgcagg aagcgcagcg
     9181 agaaaatctc ccacgccata cccacgtcag tgaagaccac accgtaattc agaaagagaa
     9241 aacggcgagc aaattcaacg cattgccatt tgtggcccat atattcgtcg tcgatatagc
     9301 tacggaatac ggcgtcatct tcgtattcct gcggatcgag agaactgtaa tctgaagagt
     9361 agattgctac cccacctggg gcgtagccca ataatgtccc gaacggggca tcctggctgg
     9421 tcgttccttt gctcatcact ttacctttaa caatacaacc taagcagttg gcgtaattgt
     9481 tgtgctctga ttacctgctc agcgacatta accggacaga ggtcagacta atcatacacc
     9541 tcatcgcagc ggctggcgca aagggttaaa aaattcacat tctgtacagc aagtgacctg
     9601 ctacactgct tcaacactac cactgagaag gcaactcact atgacagaca atacttatca
     9661 gcccgcgaaa gtctggacgt gggataaatc cgctggcggc gcgttcgcca atatcaatcg
     9721 cccggtttct ggtccgacgc atgaaaaaac gctgccggtg ggcaaacatc cgctgcaact
     9781 ctattcactg ggaacgccga acggtcagaa agtaacgatt atgcttgagg agctgctggc
     9841 gctgggcgtt actggtgcag agtacgacgc ctggctgatt cgtattggcg atggcgatca
     9901 attctccagc ggctttgtcg aagtgaaccc aaactcgaag atcccggcgc tgcgcgacca
     9961 tacccatact ccgccgatcc gcgtgtttga gtctggatcg attctgcttt atctggcgga
    10021 gaaatttggc tacttcctgc cgcaggatct ggcaaaacgg actgaaacgc tgaactggct
    10081 gttctggtta cagggtgccg cgccgttcct cggcggtggt tttggtcact tttaccatta
    10141 cgcgccggtg aaaattgagt acgccatcaa ccgctttact atggaagcca agcgcctgct
    10201 cgacgtgctg gataagcaac tggcgcagca taagtttgtt gcgggcgatg agtacaccat
    10261 tgcggatatg gcgatttggc cgtggtttgg caacgtggtg ctcggcggcg tgtatgatgc
    10321 cgcagagttt ctggatgcgg gaagttataa acatgtgcaa cgctgggcga aagaagtggg
    10381 cgaacgtccg gcggtgaagc gtgggcgtat tgttaaccgc accaacggac cgctgaacga
    10441 gcagttgcat gaacgccatg acgccagtga tttcgagacg aatacggaag ataagcgtca
    10501 ggggtaaggg ttggtgttcg tcgcagcaag ccatccaggc cgaggtaggc cggaaaaggc
    10561 gttcacgccg catccggcaa tcgtgcataa tgcctgatgc gacgctgccg cgtcttatca
    10621 ggcctacaat cggcacccga acggtaggcc ggataaggcg ttcacgccgc atccggcaat
    10681 cgtgcacaat gcctgatgcg acgctg
//
LOCUS       DADXDL010000124        10614 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.124, whole genome shotgun sequence.
ACCESSION   DADXDL010000124 DADXDL010000000
VERSION     DADXDL010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10614)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10614)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10614
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.124"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            202..2343
                     /locus_tag="IRB70_004308"
     CDS             202..2343
                     /locus_tag="IRB70_004308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TonB-dependent siderophore receptor"
                     /protein_id="HBC0634149.1"
                     /translation="MAKFTPSFSGIKGRALFSLLFAAPMIHATDTATTKDGETITVTA
                     NANTATEATDGYQPLSTSTATLTDMPMLDIPQVVNTVSDQVLENQNATTLDEALYNVS
                     NVVQTNTLGGTQDAFVRRGFGANRDGSIMTNGLRTVLPRSFNAATERVEVLKGPASTL
                     YGILDPGGLINVVTKRPEKTFHGSVSATSSSFGGGTGQLDITGPIEGTQLAYRLTGEV
                     QDEDYWRNFGKERSTFIAPSLTWFGDNATVTMLYSHRDYKTPFDRGTIFDLTTKQPVN
                     VDRKIRFDEPFNITDGQSDLAQLNAEYHLNSQWTARFDYSYSQDKYSDNQARVTAYDA
                     TTGTLTRRVDATQGSTQRMHATRADLQGNVDIAGFYNEILGGVSYEYYDLLRTDMIRC
                     KKAKDFNIYNPVYGNTSKCTTVSASDSDQTIKQESYSAYAQDALYLTDNWIAVAGIRY
                     QYYTQYAGKGRPFNVNTDSRDEQWTPKLGLVYKLTPSVSLFANYSQTFMPQSSIASYI
                     GDLPPESSNAYEVGAKFELFDGITADIALFDIHKRNVLYTESIGDETIAKTAGRVRSR
                     GVEVDLAGALTENINIIASYGYTDAKVLEDPDYAGKPLPNVPRHTGSLFLTYDIHNMP
                     GNNTLTFGGGGHGVSRRSATNGADYYLPGYFVADAFAAYKMKLQYPVTLQLNVKNLFD
                     KTYYTSSIATNNLGNQIGDPREVQFTVKMEF"
     gene            complement(2407..4299)
                     /gene="parE"
                     /locus_tag="IRB70_004309"
     CDS             complement(2407..4299)
                     /gene="parE"
                     /locus_tag="IRB70_004309"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBC0634150.1"
                     /translation="MTQTYNADAIEVLTGLEPVRRRPGMYTDTTRPNHLGQEVIDNSV
                     DEALAGHAKRVDVILHADQSLEVIDDGRGMPVDIHPEEGVPAVELILCRLHAGGKFSN
                     KNYQFSGGLHGVGISVVNALSKRVEVNVRRDGQVYNIAFENGEKVQDLQVVGTCGKRN
                     TGTSVHFWPDEAFFDSPRFSVSRLTHVLKAKAVLCPGVEITFKDEINNTEQRWCYQDG
                     LNDYLAEAVNGLPTLPEKPFIGNFAGDTEAVDWALLWLPEGGELLTESYVNLIPTMQG
                     GTHVNGLRQGLLDAMREFCEYRNILPRGVKLSAEDIWDRCAYVLSVKMQDPQFAGQTK
                     ERLSSRQCAAFVSGVVKDAFILWLNQNVQAAELLAEMAISSAQRRMRAAKKVVRKKLT
                     SGPALPGKLADCTAQDLNRTELFLVEGDSAGGSAKQARDREYQAIMPLKGKILNTWEV
                     SSDEVLAAQEVHDISVAIGIDPDSDDLSQLRYGKICILADADSDGLHIATLLCALFVK
                     HFRALVKHGHVYVALPPLYRIDLGKEVYYALTEEEKEGVLEQLKRKKGKPNVQRFKGL
                     GEMNPMQLRETTLDPNTRRLVQLTIDDEDDQRTDAMMDMLLAKKRSEDRRNWLQEKGD
                     MAEIEV"
     gene            complement(4328..4909)
                     /gene="yqiA"
                     /locus_tag="IRB70_004310"
     CDS             complement(4328..4909)
                     /gene="yqiA"
                     /locus_tag="IRB70_004310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase YqiA"
                     /protein_id="HBC0634151.1"
                     /translation="MSTLLYLHGFNSSPRSAKASLLKNWLAEHHPDVEMIIPQLPPYP
                     SDAAELLESIVLEHGGDSLGIVGSSLGGYYATWLSQCFMLPAVVVNPAVRPFELLTDY
                     LGQNENPYTGQQYVLESRHIYDLKVMQIDPLEAPDLIWLLQQTGDEVLDYRQAVAYYA
                     SCRQTVIEGGNHAFTGFEDYFNPIVDFLGLHHL"
     gene            complement(4909..5736)
                     /gene="cpdA"
                     /locus_tag="IRB70_004311"
     CDS             complement(4909..5736)
                     /gene="cpdA"
                     /locus_tag="IRB70_004311"
                     /EC_number="3.1.4.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3',5'-cyclic-AMP phosphodiesterase"
                     /protein_id="HBC0634152.1"
                     /translation="MESLLTLPLAGEARVRILQITDTHLFAQKHEALLGVNTWESYQA
                     VLEAIRPHQHEFDLIVATGDLAQDQSSAAYQHFAEGIASFRAPCVWLPGNHDFQPAMY
                     SALQDAGISPAKRVFIGEQWQILLLDSQVFGVPHGELSEFQLEWLERKLADAPERHTL
                     LLLHHHPLPAGCSWLDQHSLRNAGELDTVLAKFPHVKYLLCGHIHQELDLDWNGRRLL
                     ATPSTCVQFKPHCSNFTLDTIAPGWRTLELHADGTLTTEVHRLADTRFQPDTASEGY"
     gene            complement(5761..6183)
                     /locus_tag="IRB70_004312"
     CDS             complement(5761..6183)
                     /locus_tag="IRB70_004312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1249 family protein"
                     /protein_id="HBC0634153.1"
                     /translation="MKRYTPDFPEMMRLCEMNFSQLRRLLPRNDAPGETVSYQVANAQ
                     YRLTIVESTRYTTLVTIEQTAPAISYWSLPSMTVRLYHDAMVAEVCSSQQIFRFKARY
                     DYPNKKLHQRDEKHQINQFLADWLRYCLAHGAMAIPVY"
     gene            complement(6184..6813)
                     /gene="nudF"
                     /locus_tag="IRB70_004313"
     CDS             complement(6184..6813)
                     /gene="nudF"
                     /locus_tag="IRB70_004313"
                     /EC_number="3.6.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ADP-ribose diphosphatase"
                     /protein_id="HBC0634154.1"
                     /translation="MLKPDNLPVTFGKNDVEIIARETLYRGFFSLDLYRFRHRLFNGQ
                     MSHEVRREIFERGHAAVLLPFDPVRDEVVLIEQIRIAAYDTSETPWLLEMVAGMIEEG
                     ESVEDVARREAIEEAGLIVKRTKPVLSFLASPGGTSERSSIMVGEVDATTASGIHGLA
                     DENEDIRVHVVSREQAYQWVEEGKIDNAASVIALQWLQLHHQALKNEWA"
     gene            7018..8499
                     /gene="tolC"
                     /locus_tag="IRB70_004314"
     CDS             7018..8499
                     /gene="tolC"
                     /locus_tag="IRB70_004314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417507.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane channel protein TolC"
                     /protein_id="HBC0634155.1"
                     /translation="MKKLLPILIGLSLSGFSSLSQAENLMQVYQQARLSNPELRKSAA
                     DRDAAFEKINEARSPLLPQLGLGADYTYSNGYRDANGINSNATSASLQLTQSIFDMSK
                     WRALTLQEKAAGIQDVTYQTDQQTLILNTATAYFNVLNAIDVLSYTQAQKEAIYRQLD
                     QTTQRFNVGLVAITDVQNARAQYDTVLANEVTARNNLDNAVEQLRQITGNYYPELAAL
                     NVENFKTDKPQPVNALLKEAEKRNLSLLQARLSQDLAREQIRQAQDGHLPTLDLTAST
                     GISDTSYSGSKTRGAAGTQYDDSNMGQNKVGLSFSLPIYQGGMVNSQVKQAQYNFVGA
                     SEQLESAHRSVVQTVRSSFNNINASISSINAYKQAVVSAQSSLDAMEAGYSVGTRTIV
                     DVLDATTTLYNAKQELANARYNYLINQLNIKSALGTLNEQDLLALNNALSKPVSTNPE
                     NVAPQTPEQNAIADGYAPDSPAPVVQQTSARTTTSNGHNPFRN"
     gene            8647..9318
                     /locus_tag="IRB70_004315"
     CDS             8647..9318
                     /locus_tag="IRB70_004315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417509.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1190 family protein"
                     /protein_id="HBC0634156.1"
                     /translation="MKRTKSIRHASFRKNWSARHLTPVALAVATVFMLAGCEKSDETV
                     SLYQNADDCSAANPGKSAECTTAYNNALKEAERTAPKYATREDCVAEFGEGQCQQAPA
                     QAGMAPENQAQAQQSSGSFWMPLMAGYMMGRLMGGGAGFAQQPLFSSKNPASPAYGKY
                     TDATGKNYGAAQPGRTMTVPKTAMAPKPATTTTVTRGGFGESVAKQSTMQRSATGTSS
                     RSMGG"
     gene            9324..10484
                     /locus_tag="IRB70_004316"
     CDS             9324..10484
                     /locus_tag="IRB70_004316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionylspermidine synthase family protein"
                     /protein_id="HBC0634157.1"
                     /translation="MERVSITERPDWREKAHEYGFNFHTMYGEPYWCEDAYYKLTLAQ
                     VEKLEEVTAELHQMCLKVVEKVIASDELMTKFRIPKHTWSFVRQSWLTHQPSLYSRLD
                     LAWDGTGEPKLLENNADTPTSLYEAAFFQWIWLEDQLNAGNLPEGSDQFNSLQEKLID
                     RFVELREQYGFQLLHLTCCRDTVEDRGTIQYLQDCATEAEIATEFLYIDDIGLGEKGQ
                     FTDLQDQVISNLFKLYPWEFMLREMFSTKLEDAGVRWLEPAWKSIISNKALLPLLWEM
                     FPNHPNLLPAYFAEDDHPQMEKYVVKPIFSREGANVSIIENGKTIEAAEGPYGEEGMI
                     VQQFHPLPKFGDSYMLIGSWLVNDQPAGIGIREDRALITQDMSRFYPHIFVE"
BASE COUNT         2690 a         2809 c         2605 g         2510 t
ORIGIN      
        1 atcaattgaa ttgcattaac ctctcataaa aacacatgta gcaatttttt gttatttctc
       61 atttactact acatcaccgc atggttgaat gattctcaat tacatatccg atggtgaaat
      121 aacaaacgga tagtgcttag tgagcaacaa gaaacaattt tcactcacga caatccgtga
      181 gtttttggga taacagacta aatggctaag ttcacacctt cattctcagg aatcaaaggt
      241 cgggcgctct tttcactgct ctttgcagca ccaatgattc atgcaaccga cactgcaacg
      301 accaaagatg gcgaaacaat cactgttaca gcgaatgcaa ataccgcaac tgaggcgacc
      361 gatggttatc aacctctgag cacttccacg gcgacattaa ccgatatgcc gatgctggat
      421 atcccgcagg tggtcaatac ggttagcgat caggttctgg aaaatcagaa tgcgacgacg
      481 ctggatgaag cgctttataa cgtcagtaac gtggtacaga ccaatacatt aggcggaact
      541 caggacgcct ttgtacgtcg tgggtttggt gctaaccggg atggctccat catgaccaac
      601 ggcctgcgaa ctgtacttcc tcgcagtttc aacgccgcca cagaacgtgt ggaagtgcta
      661 aaaggtccgg cctccacgct gtatggcatt ctcgatcctg gtggattgat taacgtcgtg
      721 accaagcgcc cggaaaaaac attccatggt tctgtctcag ccacgtcctc cagttttggc
      781 ggaggcactg ggcaacttga tatcacaggt cccattgaag gcactcagct ggcataccgc
      841 ctgacggggg aagtgcagga tgaagattac tggcgaaact tcggtaaaga gcgcagtaca
      901 tttattgccc cgtcactcac ctggtttggt gataatgcaa cagtaactat gctctattcc
      961 catcgggact ataaaactcc gttcgatcgt ggaacgattt tcgaccttac gacgaaacag
     1021 cccgtaaacg ttgatcgaaa aatacgtttt gacgaaccgt ttaatattac agatggtcag
     1081 tccgatctgg cgcaactcaa cgcagaatat catctcaata gccagtggac agcgcgcttt
     1141 gattacagct acagccagga taaatacagc gataatcagg cgcgtgttac cgcgtatgat
     1201 gcaacgacag gaacactgac acggcgtgtt gatgcaactc agggatctac ccagcgtatg
     1261 catgctactc gtgcggatct gcaagggaat gttgatattg ccggattcta taatgagatt
     1321 ctgggtgggg tgtcatatga atattatgat cttctgcgta cagatatgat tcgctgtaaa
     1381 aaagctaaag atttcaatat ttacaaccct gtttatggta ataccagcaa atgtacaacg
     1441 gtttcggcgt cggacagtga tcagacgatc aaacaggaga gctactcagc gtatgcacag
     1501 gacgcactct atctgaccga taactggatt gccgtcgccg ggatccgcta tcagtattac
     1561 acgcagtatg cgggtaaagg ccgtcctttt aatgtcaata ctgacagccg cgatgaacaa
     1621 tggactccca aactggggtt agtctacaaa ctgacgccat cggtatcctt atttgccaat
     1681 tattcgcaaa catttatgcc gcagtcgtca attgccagct acattggcga tcttccaccg
     1741 gaatcatcta atgcttacga agtcggggca aaattcgagc tattcgatgg tatcaccgca
     1801 gatattgcgc tgtttgatat acataaacgt aacgtgttgt ataccgaaag tattggtgat
     1861 gaaaccattg ccaaaacggc aggccgtgtt cgttcaagag gggtagaagt cgaccttgcg
     1921 ggagcattaa ctgaaaacat taatatcatt gccagctacg gctataccga tgctaaggtt
     1981 ctggaggatc ctgattatgc agggaaacca ttgccgaatg ttcctcgtca taccggttcg
     2041 ctattcctga cctatgatat tcataacatg ccaggcaata atacgctgac atttggcggt
     2101 ggtggacatg gtgtaagccg tcgttcggca accaatgggg ctgactatta tctgccaggc
     2161 tattttgttg ccgatgcctt cgccgcatac aaaatgaaat tgcagtatcc ggtcacactg
     2221 caattaaacg tcaaaaacct gtttgataaa acgtattaca cctcttccat cgccacaaat
     2281 aatctgggga atcagattgg cgatccgcgt gaagtgcaat tcacggtgaa aatggaattt
     2341 tgatcaaaaa agcccggtat acacttgtat accgggctat tttttattct tctggcggga
     2401 ggattatcag acctcaatct ctgccatgtc gcctttctct tgcaaccagt tgcggcgatc
     2461 ttccgagcgt ttcttcgcca gcagcatatc catcatcgcg tccgtacgct gatcgtcttc
     2521 atcatcgata gtcaactgca ccagacggcg agtgttcgga tcaagcgtgg tttcgcgcaa
     2581 ttgcatcggg ttcatttccc cgagaccttt aaaacgctgg acgtttggct tgcctttctt
     2641 gcgttttaat tgctcaagta cgccctcttt ctcttcttcc gtcagcgcgt aataaacctc
     2701 tttcccgagg tcaatacggt agagcggtgg cagtgcaacg taaacgtgac cgtgtttcac
     2761 caatgcgcgg aagtgtttta caaacaaagc gcagagcagc gtggcaatgt gcagaccatc
     2821 ggagtcagca tccgccagga tacagatctt gccgtaacga agctggctca aatcgtcgct
     2881 gtcaggatcg ataccgatag ctaccgaaat atcgtgcact tcctgcgcag ccagcacttc
     2941 gtcggaagag acttcccagg tgttaaggat cttacctttc agtggcatga tcgcctgata
     3001 ttcgcgatcg cgcgcctgct tggcagatcc gcctgcggag tcaccttcca caaggaacag
     3061 ctcggtacgg ttaagatcct gcgcggtaca gtcagccagt ttgccaggca gcgccgggcc
     3121 gctggttagc tttttacgca ccactttttt agccgcacgc atacgacgct gggcgctgga
     3181 aatcgccatc tctgccaaca gctccgccgc ctgaacgttc tggttcagcc acaggatgaa
     3241 ggcatctttc accacgcccg aaacgaatgc cgcacactga cgcgaagaga gacgttcttt
     3301 ggtctgcccg gcaaactgcg gatcctgcat ttttactgac agcacatagg cgcagcgatc
     3361 ccagatatct tccgccgaca gctttacacc gcgcggcaga atgttgcgat attcacagaa
     3421 ctcacgcatc gcgtccagca ggccctgacg caggccatta acgtgcgtac caccctgcat
     3481 cgttgggatc aggttgacgt agctttcggt cagcagttca ccgccttccg gcagccacag
     3541 tagcgcccag tccaccgctt cagtatcgcc agcgaaatta ccgataaacg gtttttctgg
     3601 cagcgtcggt aaaccgttta ccgcttccgc caggtaatca ttcagaccgt cctgatagca
     3661 ccagcgctgt tcggtgttgt tgatctcatc tttaaaggtg atctcaacac ctgggcacag
     3721 taccgctttg gctttcagca catgcgtcag gcgtgaaaca gaaaaacgcg ggctgtcaaa
     3781 gaaggcttca tccggccaga agtgcacgct ggtaccggta ttgcgtttac cacaggtgcc
     3841 gacaacctgt aaatcttgca ccttttcgcc attttcaaag gcgatgttat aaacctgacc
     3901 atcgcggcgt acgttaactt ctacgcgctt cgacagggcg ttaaccaccg aaatccccac
     3961 gccatgcagg ccgccagaga actggtaatt tttgttagag aatttaccgc ccgcgtgcag
     4021 acggcaaaga atcagttcaa ccgccggtac accctcttcc gggtgaatat ccaccggcat
     4081 cccacgacca tcgtcaataa cttctaacga ctggtcagca tgtaagatta cgtccacgcg
     4141 ttttgcgtga cccgccagtg cttcatcgac actgttatca ataacttctt gccccaaatg
     4201 gttagggcga gtggtatcgg tatacatccc cggacggcgg cgaaccggct caagcccggt
     4261 gagtacctca atggcatcag cgttataagt ttgcgtcatg gtttaagtta gcaattcgag
     4321 ttgatcgtca gagatggtgc agaccaagaa aatcgacgat cgggttgaaa taatcttcga
     4381 agcccgtgaa tgcgtggttg ccgccttcta tgacagtctg gcggcaggaa gcgtagtacg
     4441 ccaccgcctg gcggtaatcc agcacttcat ctcccgtctg ttgcagcagc cagatcaaat
     4501 ccggcgcttc cagcgggtca atctgcatga ctttgagatc gtaaatatgg cgtgactcta
     4561 gcacatattg ctgcccggtg taggggttct cgttctgacc gagatagtcc gttagcagtt
     4621 caaacgggcg caccgccggg ttgaccacca ctgcgggcaa cataaaacat tgcgacaacc
     4681 aggtggcgta atatcccccc agtgacgaac cgacaatacc cagcgaatcg ccgccatgtt
     4741 ccaggacaat ggattccagc agttctgccg catcggaagg atacggcggc aactgcggaa
     4801 tgatcatctc tacgtcaggg tgatgttccg ccaaccagtt ttttaacaag ctcgcttttg
     4861 cagagcgcgg cgagctgttg aaaccgtgta aataaagaag cgtagacatc agtagccttc
     4921 tgaagcggta tcaggttgga aacgtgtgtc cgccaggcga tgcacctcgg tggtcagcgt
     4981 gccatcagca tgtaactcga gagtacgcca gccgggcgcg atggtgtcca gcgtaaagtt
     5041 ggaacagtgc ggcttaaact gcacacaggt cgacggcgtt gccagcaggc ggcgaccgtt
     5101 ccagtcgaga tccagctcct gatgaatatg accgcacagc aagtatttga cgtgcggaaa
     5161 cttcgccagc acggtatcca gttcgcccgc gttacgcagg ctgtgttgat caagccaact
     5221 acaacccgca ggtagcggat gatgatgcag cagcagcaac gtatggcgtt ctggcgcatc
     5281 ggccagttta cgttccagcc actcaagctg aaactcgctc agctcaccgt gcggcacgcc
     5341 aaacacctgg ctatccagca acaggatttg ccattgctca ccaataaaca cgcgcttcgc
     5401 cggggagata cccgcatcct gtaacgcgct gtacatcgcg ggctggaaat cgtggttgcc
     5461 cggcagccag acgcagggcg cacgaaaact tgcgatgcct tcagcgaaat gctgataggc
     5521 cgcagaggat tgatcctgcg ctaaatcacc tgtcgcgaca atcaggtcga attcgtgctg
     5581 gtgtggccga atcgcctcca gcaccgcctg gtagctttcc caggtgttta cccctaacag
     5641 ggcttcgtgc ttttgtgcaa acaggtgagt gtcggtaatt tgtaaaatcc tgactctggc
     5701 ctcaccagcc agaggaaggg ttaacaggct ttccaaatgg tgtccttagg tttcacgacg
     5761 ctaataaacc ggaatcgcca tcgctccatg tgctaaacag tatcgcaacc agtccgctag
     5821 aaactgatta atttgatgct tttcgtcgcg ttgatgcaac tttttattag gataatcata
     5881 ccgcgctttg aagcgaaaaa tctgctggct tgaacacact tcagccacca tcgcgtcatg
     5941 atacagacgc accgtcattg acggaaggct ccagtaactg atcgcgggcg cagtctgttc
     6001 tattgtcacc agggtagtgt atcgggtcga ttccacaatc gtcagccgat attgtgcgtt
     6061 tgccacctga tagcttacag tttcgccggg tgcgtcattg cgcggtaaca aacggcgcaa
     6121 ttgtgaaaag ttcatctcgc acaggcgcat catttcagga aagtcaggtg tgtaacgctt
     6181 catttatgcc cactcatttt ttaacgcttg atgatgcagc tgcagccatt gcaaagcgat
     6241 gaccgacgct gcgttgtcga ttttcccctc ttctacccac tggtatgcct gttcccggct
     6301 taccacatga acgcgaatat cttcgttttc atcagccaga ccgtgaatac cgcttgcggt
     6361 cgtggcgtcc acttcgccca ccataattga cgaacgctca ctggtgcccc ccgggcttgc
     6421 caggaaactt aacaccggtt tggtccgttt gactatcagc cccgcctctt caatcgcttc
     6481 gcgacgggca acatcttcca cactttcacc ctcttcaatc atcccggcaa ccatctccag
     6541 tagccagggg gtttcgctag tgtcgtacgc ggcaattcga atctgctcaa tcagcacaac
     6601 ttcatcacgc actgggtcaa agggtagcaa gactgcggcg tgaccgcgct caaaaatttc
     6661 ccgccgtacc tcatgactca tttgcccgtt gaatagacga tgacgaaatc tataaagatc
     6721 taatgaaaaa aagccgcgat aaagtgtttc tcgtgcaata atttctacat cgtttttgcc
     6781 aaatgtaacg ggcaggttgt ctggcttaag cattgttaat gtcctggcac taatagtgaa
     6841 ttaaatgtga atttcagcga cgtttgactg ccgtttgagc agtcatgtgt taaattgagg
     6901 cacattaacg ccctatggca cgtaacgcca accttttgcg gtagcggctt ctgctagaat
     6961 ccgcaataat tttacagttt gatcgcgcta aatactgctt caccacaagg aatgcaaatg
     7021 aagaaattgc tccccattct tatcggcctg agcctttctg gtttcagttc gttgagccag
     7081 gccgagaacc tgatgcaagt ttatcagcaa gcacgcctta gtaacccgga attgcgtaag
     7141 tctgccgccg atcgtgatgc tgcctttgaa aaaattaatg aagcgcgcag tccattactg
     7201 ccacagctag gtttaggtgc agattacacc tatagcaacg gctaccgcga cgcgaacggc
     7261 atcaactcta acgcgaccag tgcgtccctg cagttaactc aatccatttt tgatatgtcg
     7321 aaatggcgtg cgttaacgct gcaggaaaaa gcagctggga ttcaggacgt cacgtatcag
     7381 accgatcaac aaaccttgat cctcaacacc gcgaccgctt atttcaacgt gttgaatgct
     7441 attgacgttc tttcctatac acaggcgcaa aaagaagcga tctaccgtca attggatcaa
     7501 accacccaac gttttaacgt gggcctggta gcgatcactg acgtgcagaa cgcccgcgca
     7561 cagtacgata ccgtgctggc gaacgaagtg accgcacgta ataaccttga taacgcggta
     7621 gagcagctgc gccagatcac cggtaactac tatccggaac tggcggcgct gaatgtcgaa
     7681 aactttaaaa ccgacaaacc acagccagtt aacgcgctgc tgaaagaagc cgaaaaacgc
     7741 aacctgtcgc tgttacaggc acgcttgagc caggacctgg cgcgcgagca aattcgccag
     7801 gcgcaggatg gtcacttacc gactctggat ttaacggctt ctaccgggat ttctgacacc
     7861 tcttatagcg gttcgaaaac ccgtggtgcc gctggtaccc agtatgacga cagcaatatg
     7921 ggccagaaca aagtgggcct gagcttctcg ctgccgattt atcagggcgg tatggttaat
     7981 tcgcaggtga aacaggcaca gtacaacttt gtcggtgcca gcgagcaact ggaaagcgcg
     8041 caccgtagcg tcgtgcaaac cgtgcgttct tccttcaaca acattaatgc atctatcagt
     8101 agcattaacg cctacaaaca ggccgtggtt tccgcccaaa gctcattgga cgcgatggaa
     8161 gcgggttact cggttggtac gcgtaccatt gttgatgtgt tggatgcgac caccacgctg
     8221 tacaacgcta agcaagagct ggcaaatgcg cgttataact acctgattaa ccagctgaat
     8281 attaagtcag ctctgggtac gttgaacgag caggatctgc tggcactgaa caatgcgctg
     8341 agcaaaccgg tttccactaa tccggaaaac gttgccccgc aaacgccgga acagaatgct
     8401 attgctgatg gttatgcgcc tgatagcccg gcacccgtcg ttcagcaaac atccgcacgc
     8461 actaccacca gtaacggcca taaccctttc cgtaactgat gacgacgacg gggcttcggc
     8521 cccgtctgaa cgtaaggcaa cgtaaagata cgggttatct gccgcattcc tcccccttct
     8581 cgcttcaatt tcgaccagcc atcctctatt ctgatgggta tttaccactg gtcccggaag
     8641 acaaaaatga aacggacaaa atccatacgc cacgcatcgt tccgcaaaaa ctggagcgca
     8701 cgccatctga caccagtcgc tctcgcggtt gccactgttt ttatgctggc gggctgtgaa
     8761 aagagtgatg aaacagtgtc tctctatcaa aatgctgacg actgttcagc tgcaaaccca
     8821 ggcaaaagcg ccgaatgtac caccgcgtac aacaatgcgc tgaaagaagc cgaacgtact
     8881 gcgccgaaat acgccacccg tgaagactgt gttgctgaat ttggtgaagg tcagtgccag
     8941 caggcaccag cccaggctgg catggcacca gaaaaccagg cgcaggccca gcaatccagc
     9001 gggagtttct ggatgccgct gatggccggt tacatgatgg ggcgtctgat gggcggcggc
     9061 gcgggatttg cacagcagcc gctgttctcc tcgaaaaacc cggccagccc ggcttacggt
     9121 aaatataccg acgcgaccgg taaaaactat ggcgcagccc agccaggccg caccatgacc
     9181 gtaccgaaga cggcaatggc accaaaaccg gcgaccacca ccaccgttac tcgtggcggt
     9241 tttggtgaat ctgttgccaa acaaagcact atgcagcgta gcgcaaccgg cacctcttct
     9301 cgttcaatgg gtggctgata ccgatggaaa gagtcagtat taccgagcgc ccggactggc
     9361 gcgaaaaagc ccacgaatac ggtttcaatt ttcacaccat gtacggcgag ccgtactggt
     9421 gtgaagatgc ttactacaag ttgaccctcg ctcaggttga aaagctggaa gaagtcaccg
     9481 ccgaactgca ccagatgtgc ctgaaagtgg tggaaaaagt gatcgccagc gatgagctga
     9541 tgaccaaatt ccgcatacca aaacacacct ggagttttgt gcgccagtca tggctgacgc
     9601 accagccatc gctttattcg cgtcttgatc tggcgtggga tggcactggc gaacctaagc
     9661 ttctggaaaa taacgccgat acgccaacgt cactatacga ggcggcgttc tttcagtgga
     9721 tctggctgga agatcagctt aacgccggta acttgccgga gggcagcgac cagtttaaca
     9781 gtttgcaaga aaagctgatc gatcgcttcg ttgagctgcg tgaacagtat ggcttccagt
     9841 tgctgcatct cacctgctgt cgcgacacgg tggaagatcg cggaaccatt cagtatttgc
     9901 aggactgcgc gacggaagct gaaatcgcta ccgagttcct ctacatcgac gatatcgggt
     9961 taggtgaaaa aggtcagttc acggatttac aggatcaggt gatttccaac ctgttcaagc
    10021 tgtatccgtg ggaatttatg ttgcgtgaga tgttctccac caagctggag gatgcaggcg
    10081 tacgctggct ggaaccggcg tggaagagca ttatctccaa caaagcgctt ctaccgctac
    10141 tgtgggagat gttcccgaat cacccgaacc tgctgcccgc ttattttgcg gaagatgatc
    10201 atccgcaaat ggaaaaatat gtggttaaac cgatcttctc ccgtgaaggc gcaaacgtgt
    10261 cgatcattga gaacggcaaa accattgaag cagcggaagg tccgtatggc gaagaaggga
    10321 tgattgttca gcaattccac ccgttaccga aattcggcga cagctatatg ctgattggta
    10381 gctggctggt gaacgatcaa cctgccggaa ttggcattcg tgaagaccgt gcattgatca
    10441 cccaggatat gtctcggttt tatccgcata tttttgttga gtaatacagc ttaatattgc
    10501 cccgataagc ggggcaatct cttataatcc accattcata attcccatca atatataaac
    10561 acataaacct ttatttaaca ttaatactca atttaatgtt aaatcgtcat atgc
//
LOCUS       DADXDL010000125        10549 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.125, whole genome shotgun sequence.
ACCESSION   DADXDL010000125 DADXDL010000000
VERSION     DADXDL010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10549)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10549)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10549
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.125"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            111..611
                     /gene="tssB"
                     /locus_tag="IRB70_004317"
     CDS             111..611
                     /gene="tssB"
                     /locus_tag="IRB70_004317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     small subunit"
                     /protein_id="HBC0634158.1"
                     /translation="MSKKFEGSVAPRERINISYVPKTDGQTAEVELPLNMLVVGDTGN
                     TQETSPLDERQAVSVNKHNFGAVMAEAAIGLNFTVPATLKGSTTDDELNVALNIKSLD
                     DFSPDSVARQVPEVNKLLELREALTALKGPMGNLPAFRTQLQALLENEESREQLLKEI
                     GQVSNK"
     gene            646..870
                     /locus_tag="IRB70_004318"
     CDS             646..870
                     /locus_tag="IRB70_004318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634159.1"
                     /translation="MTAHKNISGTYHLSVADVLQVVYQVCFSPSVEINQDGVAALITT
                     LDRRISDLLDEIIHFCEFQQSASHWQRVLH"
     gene            921..2396
                     /gene="tssC"
                     /locus_tag="IRB70_004319"
     CDS             921..2396
                     /gene="tssC"
                     /locus_tag="IRB70_004319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001501045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system contractile sheath
                     large subunit"
                     /protein_id="HBC0634160.1"
                     /translation="MSLQEEELVSSHAGQPEQASSLLDQIMAQTRIQPGSEGYDVARQ
                     GVTAFIASILQSTASAEPVNKLAVDSMIADIDERISRQMDVIIHAPAFQQVESFWRSL
                     KTMVDRVDFRENIKVNVLHVTKQELLEDFEFAPEIIQSGFYKHVYSSGFGQFGGEPIA
                     AVLGAYEFKNTAPDMKLLQYVSAVGAMAHAPFLSSVSPEFMGLNSWTELPNIKDLYAI
                     FEGPAYTKWRALRDSEDSRYLGLTAPRFLLRQPYSPTDNPVKNFNYHEDVSRNHEDYL
                     WGNTAWMLACNVADSFAKYRWCPNIIGPQSGGAVKDLPVHLFETMGQIQAKIPTEVLV
                     TDRREFELAEEGFITLTMRKDSDNAAFFSANSVQKPKHFPGKDAETNYKLGTQLPYLF
                     IINRLAHYIKVLQREQLGSWKERSDLERELNTWIRQYVADQENPPADVRSRKPLRAAK
                     VEVMDVEGEPGWYQVALSVRPHFKFMGANFELSLVGRLDRE"
     gene            2403..2816
                     /gene="tssE"
                     /locus_tag="IRB70_004320"
     CDS             2403..2816
                     /gene="tssE"
                     /locus_tag="IRB70_004320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssE"
                     /protein_id="HBC0634161.1"
                     /translation="MIPDRERTTGSLFERMEASPARNRQGSSIHALRQSIRQNLRNIL
                     NTRSGSCRGAPELGIDEPEGAENFRQSMSRAIAQCIERYEPRISHAEVQAVVSSAASP
                     LDMTFHITAWVTFNETHEVLEFDMAPNGSQHYRVD"
     gene            2820..4670
                     /gene="tssF"
                     /locus_tag="IRB70_004321"
     CDS             2820..4670
                     /gene="tssF"
                     /locus_tag="IRB70_004321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssF"
                     /protein_id="HBC0634162.1"
                     /translation="MEFEERYFREELDYLRQLSKLLATEKPHLARFLAEKDADPDIER
                     LLEGVAFLTGNLRQKIEDEFPELTHGLIKMLWPNYLRPVPAMTLIEYTPDMDKSSVPV
                     LIPRNEQFTTNAGEIRVDEVLPSDAKKEEPPPCTFTLCRDIWLLPVRLEQIENRSTTR
                     NGVINITFSVAPGTDFRTLDLNKLRFWLGNDDNYTRDQLYLWFCEYLQGADLTVGEQH
                     IRLPEFMLKAVGFEPQDAMLPWPKNVHSGYRILQEYFCYPDAFLFFDLCGCPALPDGL
                     QAESFTLQLRFSRPLPVDIRLRRDSLRLYCAPAINLFIHHAEAITLDNRRADYPLVPS
                     RHYPEHYDVFSVNGVVSQVQDMFRKKDLGRPVSTQAARQWPAFESFSHQMEYSRKREV
                     VYWHHRTKTSLFHRGFDHTLAFIHADGSYPSDESLLSNEVVSVSLTCTNRELPSQIRS
                     GDITGTTGKNAAVASFRNITRPTQPLWPVIDGSLHWSLLSAMNLNYLSLLDTDALKQV
                     IANFDRHAIHHPQTARLSQQKLDAIERLDTRPVDRLFTGIPVRGLASTLYLHPEPFVC
                     EGEMYLLGTVLSHFLSLYASVNSFHMLTVVNTESQETWKWTERTGQHPLI"
     gene            4634..5716
                     /gene="tssG"
                     /locus_tag="IRB70_004322"
     CDS             4634..5716
                     /gene="tssG"
                     /locus_tag="IRB70_004322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssG"
                     /protein_id="HBC0634163.1"
                     /translation="MDGKNRAASSYLSPGHPPADKEQNDPLAQVFHNACSYNFFAMAE
                     LLHRLAQGEKGTPELSLRDDPAQETLRFSADASLAFPCSDISGLKRDTSGAFRMTTTF
                     MGLQGSQSPLPGYYLDHLAWKAVHEQSPVGDFLDMFSHRLTQFVWHIWRKYRYHISFR
                     NGGVDAFSQRMYSLVGLGHRQLRDKLAINHSKMLAYSGILANPGRSPEIICGLVSHCF
                     DLSDVTLQNWQRRKVDIEPDQQNSLGSYSLRNGEKLAGRSVLGNFVLGTRVPDLSGKF
                     QLSITSLTRKQLLSFLPSGENFLPLTMFVSFILRDQLAWDLHLGLAPEQVGAMRLGDN
                     KSALLGWTSFLGTPEERPSVTIRVRS"
     gene            5741..7021
                     /gene="tagH"
                     /locus_tag="IRB70_004323"
     CDS             5741..7021
                     /gene="tagH"
                     /locus_tag="IRB70_004323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated FHA domain
                     protein TagH"
                     /protein_id="HBC0634164.1"
                     /translation="MPEEKLQTLSLQVINGSELESGRAARCLFTQQGNVGHGPECHWS
                     VQDRQQSIPAQAFTVILHDGTFCLRPQTAQLWLNQAKVTATSDLIQLRQGDEIQIGRL
                     MVRVHLNRGDIPHYDEEMATPETIVTNRDMLTDTLLSTEGAPHYPGMTHRHQLADTVV
                     NGFSADPLQALQSESLITAGDPLSGIAAVRPSAPLSDPASNGGINTPFMDLPPIYASP
                     GERNDDVSVAEMAQRHLAVTPLLRGLGGSLTVSNSDDADDFLEEAGRTLQAAIKGLLD
                     LQQQRNSLSDKHLRPLEDNPLRLNMDYATALDVMFAEGKSPVHLAAPAAVSESLRNVR
                     HHEEANRAAIVESLRVLLDAFSPQNLLRRFVQYRRSHELRQPLDDAGAWQMYSHYYEE
                     LASDRQQGFEMLFNEVYAQVYDRVLREKQREPEA"
     gene            7018..7542
                     /gene="tssJ"
                     /locus_tag="IRB70_004324"
     CDS             7018..7542
                     /gene="tssJ"
                     /locus_tag="IRB70_004324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system lipoprotein TssJ"
                     /protein_id="HBC0634165.1"
                     /translation="MNRKAFLACVLMCVILTGCETAKKISEVIKNPDIQVGSLKEQPS
                     EITVTLLTEPDTNTNAEGESAAVDVQLVYLTDDSKLLAADYDQIASTPLPDVLGKNYI
                     DHQDFNLLPDTIKTLPPVKLDEKTQFIGVVAYFSDDQATEWKQIETVEGTGHHYRLLV
                     HVRQSSIEMKKEDE"
     gene            7545..8876
                     /gene="tssK"
                     /locus_tag="IRB70_004325"
     CDS             7545..8876
                     /gene="tssK"
                     /locus_tag="IRB70_004325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system baseplate subunit TssK"
                     /protein_id="HBC0634166.1"
                     /translation="MATTRNKVMWQEGMLMRPHHFQQQQRYNDYLDNQRFRAMNDLSW
                     GFTELTLNNELLAQGKIMIDSASGTLPDGTVFSIPDQDALPDPLHPQNFPDERSRNIY
                     LALPVASDVRNEISDGRRIGRYRLNYADVRDLHSEEGDARTLTLGQLTPRIMSGAEDM
                     SAYITLPLCRISDRHADGSLTLDDDFIPSCQNIQVSKKLRVYLKEVQGAIGGRASDLA
                     NRIGSPAQSGIADVAEFMMLQLLNRNQTRFTHRARRSQLHPEDFYLDLAGLLGELMTF
                     TEPSRLPCPLDVYDHHDLTKTFKTLLPEVKRALHTVLSPRAVNLPLHLRDGIWQADIH
                     DTELLQSATFVLAVAANMPVDQIQRQFIQQSKISSPEKIRNMVSVQIPGIPLRALMVA
                     PRQLPYHSGFSYFELDKSGQAWAEIAAAGAVALHVSGSFPDLNMQLWAIRG"
     gene            8881..9642
                     /gene="icmH"
                     /locus_tag="IRB70_004326"
     CDS             8881..9642
                     /gene="icmH"
                     /locus_tag="IRB70_004326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IVB secretion system protein IcmH/DotU"
                     /protein_id="HBC0634167.1"
                     /translation="MDEESLSLPPFIGHDEKGQRDYHLALRGNSLNPMIDAATPLLGM
                     VMRLSTMNSQTMPEHLFAQVVTDVQAVEQLLQEQGYEPGVIISFRYILCTFIDEAALG
                     NGWSNKNEWIKQSLLVHFHNEAWGGEKVFILLERLIREPKRYQDLLEFLWLCFSLGFR
                     GRYKVAAQDQGEFEQIYRRLYHVLHKLRGDAPFPLLHQDKKNQGGRYQLISRLTIKHI
                     FCGGVVVLALFYLFYLLRLDSQTQDILHQLNKLLR"
     gene            9651..>10549
                     /locus_tag="IRB70_004327"
     CDS             9651..>10549
                     /locus_tag="IRB70_004327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ATPase TssH"
                     /protein_id="HBC0634168.1"
                     /translation="MIQIDLPTLVKRLNLFSRQALEMAASECMSQQAAEITVSHVLIQ
                     MLAMPRSDLRVITRQGDIGMEELRQALTVENYTTARSADSYPAFSPMLVEWLKEGWLL
                     ASVEMQHSELRGGVLLLALLHSPLRYIPPAAARLLTGINRDRLQQDFVQWTQESAESV
                     VPDADGKGAGTLTDAADTLLARYAKNMTEDARNGRLDPVLCRDHEIDLMIDILCRRRK
                     NNPVVVGEAGVGKSALIEGLALRIVAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEK
                     RFKGLMAEVISSPVPVILFIDEA"
BASE COUNT         2452 a         2877 c         2865 g         2355 t
ORIGIN      
        1 gagtggtgat tttattttca ccgccattat ggcggcattg ccgatatttt tttgcggtac
       61 aaatatgccg tgttcatggc ctgtacgaga taacatgacg gatcactttt atgagcaaaa
      121 aatttgaagg cagcgtcgcg cctcgcgagc gtattaatat atcgtatgtc ccaaaaacag
      181 atggccagac ggctgaagtg gaacttccgc ttaacatgct cgttgtcggc gataccggaa
      241 atacgcagga aacatcccca ctggatgaac gtcaggcagt ttccgttaac aagcacaatt
      301 tcggtgcagt gatggctgaa gcagccattg gcctcaattt taccgtcccc gccacgctga
      361 agggaagcac aacggacgat gaactgaatg tggcgctgaa tatcaagtca ctggatgatt
      421 tttcaccaga tagcgtggcc cggcaggttc cggaagtgaa taaattgctg gaactgcgtg
      481 aagcactgac tgcactgaag gggccgatgg gtaaccttcc ggcattccgt acccagctcc
      541 aggcattgct ggaaaatgaa gagtcccgcg agcagttgct caaagaaatc ggccaggtga
      601 gcaataaata accactacta tttcattaaa cagggttatc caggcatgac ggcacacaaa
      661 aatatctccg ggacatacca cctctctgtt gcagacgttc tgcaggtggt ttaccaggta
      721 tgtttcagcc cgtccgttga aatcaaccag gatggtgtgg ctgcgctgat tacaacactg
      781 gatcgccgta tcagtgatct attggatgag attatccatt tttgtgagtt tcagcagagc
      841 gcgtcgcact ggcagcgcgt acttcactga cggcgaaaag ccggtttcag aaacacagct
      901 aaaacagaag gattttcagt atgtctttac aggaagagga actcgtttcc agtcatgccg
      961 ggcagcctga gcaggcatcg tcgctgcttg atcaaatcat ggcacagacc cgtattcagc
     1021 ccggttcgga aggttatgac gttgcccgcc agggtgtgac agcctttatt gccagcatcc
     1081 tgcaatccac tgcatctgcc gaaccggtca ataaactggc cgtggacagc atgattgcag
     1141 atattgatga acgcatcagc cgccagatgg atgtcatcat ccatgcgcct gcctttcagc
     1201 aggtcgagtc gttctggcgc tcactgaaaa ccatggtgga tcgcgttgat ttccgtgaaa
     1261 acatcaaggt caacgtgctt catgtcacca agcaggaact tctggaagac tttgagtttg
     1321 cgccagaaat tattcagtcc ggattttata agcacgttta ttcgtccggt ttcggacagt
     1381 ttggcggtga acccatcgct gccgtgctgg gcgcttatga gttcaaaaat accgcgcctg
     1441 acatgaaact gctgcaatac gtcagtgccg tgggcgcaat ggcgcacgca ccgttcctgt
     1501 cctccgtttc cccggaattt atggggctga actcgtggac cgaactgcct aatatcaaag
     1561 atctttatgc catctttgaa ggtccggcct acaccaaatg gcgcgccctg cgtgactcgg
     1621 aagattcgcg ctatttaggg cttacggcac cccgcttcct gcttcgccag ccttattcac
     1681 caacagataa ccctgttaag aactttaact atcacgaaga tgtcagccgg aaccacgaag
     1741 attatctgtg gggtaatacg gcctggatgc tggcgtgcaa tgtcgcagac agttttgcca
     1801 aataccgctg gtgtccaaat atcatcggtc cgcaaagcgg cggcgcagtg aaagatctgc
     1861 cggtgcatct gttcgaaacg atgggtcaga ttcaggccaa aatcccaacc gaggtgctgg
     1921 tcaccgatcg ccgcgaattt gaactggctg aagagggttt tatcaccctt accatgcgta
     1981 aagactctga taatgcagcc tttttctctg caaactcggt acaaaaaccg aagcactttc
     2041 cgggcaaaga cgcagaaacc aactataagc tgggtacgca gcttccttat ctcttcatca
     2101 tcaaccggtt agcgcactac atcaaggtgt tgcagcgtga acaactgggg tcatggaaag
     2161 aaaggagcga cttagaaaga gagcttaata cctggatccg tcagtatgtt gccgaccagg
     2221 aaaacccgcc tgcggacgtg cgcagccgta aacctctgcg cgctgccaaa gttgaggtta
     2281 tggatgtgga aggcgaaccc ggctggtacc aggtcgcgct gagcgtgcgg ccccatttta
     2341 aatttatggg ggcaaacttt gagctttccc tggttggccg gttagacagg gagtaacacg
     2401 ccatgatacc ggatcgggaa agaaccacag gttctctttt tgagcgtatg gaagcctcac
     2461 cggccagaaa ccggcaggga agcagtattc atgcactcag gcagtccatt cgccagaacc
     2521 tgcgaaacat tcttaatacc cggtccggta gttgccgggg tgcgcctgaa ctgggcattg
     2581 atgaaccgga aggggctgaa aacttccgcc aatcaatgag tcgggccatc gcgcaatgta
     2641 tagaacgcta tgaaccccgg atctcacacg ctgaagtgca ggctgtggtt tcatccgccg
     2701 ccagcccgct ggatatgacg tttcatatta cagcctgggt gacatttaac gaaacgcatg
     2761 aagtgcttga atttgatatg gcaccgaatg gcagccagca ttaccgggtg gactgacaga
     2821 tggaatttga agaacgctat ttccgggaag aactcgatta cctgcgccag ctcagcaagc
     2881 tgctggcaac ggaaaaaccc catctggccc gcttcctggc cgaaaaagat gcggatccgg
     2941 atattgaacg cctgctggaa ggcgtggctt ttcttaccgg caatctccgc cagaaaattg
     3001 aggatgaatt cccagaactg acgcacgggc ttattaagat gctgtggcct aattacctgc
     3061 gtccggttcc ggcaatgacc cttattgaat atacgccgga tatggataag tcttctgtgc
     3121 cggtgttaat cccccgtaat gagcagttta caaccaacgc tggggaaatc agagtcgatg
     3181 aagtgctgcc ctccgatgct aaaaaggagg agccgcctcc ctgtaccttc accctctgcc
     3241 gggatatctg gctgctgccc gttcgcctgg agcagattga aaaccgcagt acgacccgta
     3301 atggtgttat caacatcacc ttttcggtcg caccgggaac ggacttccgc acgctggatc
     3361 tgaacaaact tcgcttctgg ctcggcaatg acgacaacta tacccgtgac cagctttatt
     3421 tatggttctg tgaatacttg cagggtgccg acctgactgt gggtgaacag catattcgcc
     3481 tgcctgagtt tatgctgaaa gctgtcggtt ttgagccgca ggatgccatg ctgccctggc
     3541 cgaaaaacgt ccacagcggc taccggatcc ttcaggagta tttctgttac ccggatgcgt
     3601 ttctcttttt tgatctttgt ggttgcccgg cgttgcctga cggattgcag gctgaatcct
     3661 ttaccctgca actgcgtttt tcgcgcccat tgcccgtgga catccggctg cgccgcgatt
     3721 ctctgcgcct gtattgcgca cctgccatta atttatttat ccaccatgca gaagccatca
     3781 cgctggacaa ccggcgggca gactatccgc tggttcccag ccgccactat ccggaacatt
     3841 acgatgtctt ttccgttaac ggcgtggtga gccaggtgca ggatatgttc aggaaaaaag
     3901 atctggggcg tcctgtttcg acgcaggccg cgcgccagtg gcctgccttt gaaagtttca
     3961 gccatcagat ggaatacagc cggaagcggg aagtggtgta ctggcatcac cggaccaaaa
     4021 catccctgtt ccatcgcggc tttgatcata cccttgcttt tatacatgct gatggcagtt
     4081 atccgtcaga cgaatcgctg ctcagtaatg aagtggtttc ggtatcgctg acctgtacca
     4141 accgtgagct tccgtcacaa attcgttccg gcgatatcac cggcacaacc ggtaaaaatg
     4201 cggctgttgc ttcatttcgc aacattaccc gcccgacgca accgctctgg ccggtcattg
     4261 atggcagcct gcactggtcc ctgctctccg ccatgaacct gaattatctg tcattactag
     4321 atacggacgc gctgaagcag gtcatcgcca actttgatcg ccacgcaatc catcatccgc
     4381 agacggcgcg gctgtcacaa caaaagctgg atgccattga gcgtctggat acccgccctg
     4441 tcgatcgcct gtttacgggc attcccgtcc gggggctggc ctccacgctg tatctgcacc
     4501 cggagccgtt tgtctgtgaa ggggaaatgt atctgctcgg tacggtgctt tcgcattttc
     4561 tgtcgctgta cgccagcgtt aactcattcc acatgctgac cgttgtgaac acagaaagcc
     4621 aggagacatg gaaatggacg gaaagaaccg ggcagcatcc tcttatctga gtccgggaca
     4681 tcccccggca gataaagagc agaatgatcc gctggcacag gttttccata acgcctgctc
     4741 ttacaatttt tttgcgatgg cggagctgtt gcaccgcctg gcacagggtg aaaaggggac
     4801 accggaatta tccctgcgcg atgatccggc acaggaaacc ctgcgtttca gcgccgatgc
     4861 cagccttgcc ttcccgtgca gtgatatcag tgggctgaaa cgggatacgt caggggcatt
     4921 caggatgacc accaccttta tggggttaca ggggagccag tcgcctctcc ccggttatta
     4981 cctggatcac ctggcctgga aagcggtaca tgaacaaagt ccggtaggcg attttctgga
     5041 tatgttcagc caccgcctga cccagtttgt ctggcatatc tggcgtaagt accgctatca
     5101 catcagtttt cgtaacggcg gtgtggatgc gttctcgcag cgcatgtact cccttgtcgg
     5161 gctgggccac cgccagcttc gcgataagct ggcgattaat cacagcaaaa tgctggcgta
     5221 ttccgggatc ctggcaaatc cgggacgatc cccggaaatc atctgcggcc tggtgtcaca
     5281 ctgttttgac ttgtcagacg tgacgctgca aaactggcaa cgtcgcaagg tggatattga
     5341 accggatcag caaaacagcc tggggagcta ttcccttaga aatggcgaaa aactggccgg
     5401 aagatcggta ctgggcaact ttgttctggg tacacgggtg cccgatctca gcggaaaatt
     5461 ccagctcagt attaccagcc tgacccgaaa acagctcctc tcttttctgc cgtccggcga
     5521 aaacttcctg ccactgacga tgtttgtgtc cttcatcctg cgcgatcagc ttgcctggga
     5581 cttacatctg gggctggcac cggagcaggt gggcgcaatg cgcctgggcg ataacaaaag
     5641 tgcgctgctg ggctggacca gcttcctcgg cacaccggaa gaacgaccct cagtcaccat
     5701 cagggtacgg tcgtaaatta tgataatcac ggagcagaat atgccggaag agaaactaca
     5761 gacgctttca ttgcaggtca ttaacggcag tgagctggaa agcgggcggg cggcgcgctg
     5821 tctgttcacg cagcagggaa atgtcggcca tggccccgaa tgccactggt cggtacagga
     5881 tcgtcagcag agcattccgg ctcaggcctt taccgttatc ctgcacgatg gcacattttg
     5941 tctgcgcccg cagacggcac aactgtggct gaaccaggca aaagtcacag caacatcaga
     6001 cctgatacag ctgcgccagg gcgatgagat ccagataggg cgtctgatgg tgagggttca
     6061 tctgaaccgg ggagatatcc cccattacga tgaggaaatg gccactcccg aaaccatcgt
     6121 caccaatcgc gatatgctca cggataccct gctgtcaacg gagggtgcgc cacactatcc
     6181 gggaatgact caccggcatc agcttgcaga caccgtggta aacggttttt ctgccgatcc
     6241 actccaggca cttcagtccg aaagcctgat taccgcgggc gatccgcttt caggcattgc
     6301 ggctgtccgg ccatcggcac cgctgtccga tccggcaagt aatgggggga tcaatacgcc
     6361 gtttatggat ctgccgccca tttatgccag ccccggcgag cgtaatgatg acgtctctgt
     6421 ggcagaaatg gcgcaacgcc accttgcggt caccccctta ctgcgcggtc ttggcggctc
     6481 gcttaccgtg agcaattccg acgatgcgga tgattttctg gaggaggccg gacgcacgtt
     6541 acaggccgca ataaaaggtc tgcttgattt gcagcagcag cgtaacagcc tctcagacaa
     6601 acatttgcgc ccgctggaag ataacccgct gcgcctgaac atggattacg ccaccgcgct
     6661 cgacgtgatg tttgccgaag gtaaaagtcc ggtacatctg gcggctcccg ccgctgtcag
     6721 tgaaagcctg cgcaatgtcc gccaccacga agaagctaac cgggcggcga ttgtggagtc
     6781 gcttcgtgtc ctgctggacg ccttctcacc acaaaatctg ctgcgccgct ttgtgcagta
     6841 ccgccgcagc catgaactgc gccagccgct ggatgatgcc ggagcatggc aaatgtacag
     6901 ccattattac gaagagctgg cctccgatcg ccagcagggg tttgagatgc tgtttaacga
     6961 ggtctacgcc caggtctatg accgggtgct tcgtgaaaaa cagcgggagc cggaagcatg
     7021 aacaggaagg cgtttctggc ctgcgtgctg atgtgcgtca tattaaccgg ctgcgaaacg
     7081 gcgaaaaaaa tcagtgaggt gatcaaaaac ccggatatcc aggtcgggag cctgaaggag
     7141 caaccttcgg aaataaccgt caccctgctg accgaaccgg acaccaatac taatgcggag
     7201 ggtgaatcag ccgccgtgga tgtgcaactg gtgtacctga ctgacgactc aaaattgctg
     7261 gcagccgact atgaccagat agccagtacg ccgctaccgg atgtgctggg taaaaactat
     7321 atcgaccacc aggatttcaa cctgttgccg gacaccatca aaaccctgcc gccggtaaag
     7381 ctggatgaga aaacgcagtt tattggtgtc gtggcctatt tctccgatga ccaggccact
     7441 gaatggaaac aaatcgagac ggtggaagga accggccacc attaccgcct gctggtgcat
     7501 gtacgtcaaa gcagcatcga aatgaaaaaa gaggatgaat aattatggca accacccgca
     7561 acaaggtgat gtggcaggaa gggatgctga tgcgcccaca ccatttccag caacagcagc
     7621 gttacaacga ctacctggat aaccagcgtt tccgggccat gaatgattta tcctggggat
     7681 ttaccgaact caccctcaac aatgaactgc tggcgcaggg taagatcatg attgacagcg
     7741 cgtcaggcac actgcccgac ggcaccgtct tttctatccc cgaccaggac gcactgcccg
     7801 atccgctgca cccgcaaaat tttccggacg aaagaagccg caatatttac cttgctctgc
     7861 cggtcgccag tgatgtgaga aatgaaatca gcgacgggcg gcgaatcggg cgttaccggc
     7921 tgaattatgc cgatgtccgg gatctgcatt cagaagaagg tgacgcgcga acactgacgc
     7981 tgggtcaact gacgccgcgc attatgagcg gtgcagaaga tatgagcgcc tatattacgc
     8041 tcccgctttg ccgtatcagc gatcgccatg ccgacggctc cctgacgctg gatgacgatt
     8101 ttatcccctc ctgccagaat attcaggtca gtaagaaact gcgtgtttat ctcaaagagg
     8161 tacagggggc cattggcgga cgggcaagcg atctggcaaa ccgcattggc tctccggcgc
     8221 agagcggcat cgcggatgtg gcggaattta tgatgttgca gttacttaac cgtaaccaga
     8281 cccggtttac ccatcgcgct cgtcgatccc agctccaccc ggaagatttc taccttgatc
     8341 ttgccgggtt gctgggtgaa ctgatgacct ttaccgagcc gtcgcgcctg ccctgtccgc
     8401 ttgatgtgta tgatcatcat gacctgacca aaacatttaa aacgctgtta ccggaagtca
     8461 aacgggcgct gcataccgta ctgtcgccaa gagccgtcaa tctgccgctg catctgcgtg
     8521 acggtatctg gcaggccgat atccatgaca cagaactgct gcaatctgcc acctttgtgc
     8581 tggccgtggc ggcaaacatg ccggtcgatc agatccagcg ccagtttatc cagcagtcga
     8641 aaatttcctc gccggaaaaa atccgcaata tggtcagtgt gcagatcccc ggtattcctc
     8701 tgcgtgcact gatggtggct ccccgccagc ttccctacca ttccgggttc agctatttcg
     8761 aactcgacaa aagcggccag gcctgggctg aaatagctgc cgccggggcc gttgcactgc
     8821 atgtctccgg cagttttccg gacctgaata tgcaactgtg ggcgataaga gggtaagacg
     8881 atggatgagg agtcactgtc tctgccacca tttatcggac acgacgaaaa aggccagcgc
     8941 gactaccatc tcgcgcttcg tggcaacagc ctgaatccga tgatcgacgc agccacgccg
     9001 ctcctcggta tggtgatgcg cctttcaacc atgaacagcc agacgatgcc ggagcatctt
     9061 tttgctcagg tggtgacgga tgttcaggcc gtggagcaac tgcttcagga gcagggctac
     9121 gaaccgggcg tgattatctc gtttcgctac atcctctgca cgtttattga tgaagcggcg
     9181 ctcggtaacg gctggtcgaa caagaacgag tggatcaagc agtcattgct ggtccatttc
     9241 cacaacgaag cctggggtgg cgagaaagtt ttcatcctgc tggagcgcct gatccgtgaa
     9301 cccaaacgtt accaggatct gctggaattt ctctggctct gtttttctct gggatttcgc
     9361 gggcgctaca aagtggcagc acaggatcag ggggaatttg agcagatcta ccgccgcctg
     9421 taccacgtcc tgcataaact acgcggcgat gcccctttcc cgctgttaca ccaggacaaa
     9481 aaaaaccagg gcgggcgtta tcagctcatc agtcgcctga ccattaaaca tattttttgt
     9541 ggtggcgttg tcgtgctggc gttgttttac ctgttctatc tgttgcggct ggacagccag
     9601 acgcaggaca tcctgcacca gctaaacaaa ttacttcgat aaggacgttt atgatccaga
     9661 ttgatcttcc cacgctggta aaacggctta acctgttctc ccgccaggcg ctggagatgg
     9721 ccgcctctga atgtatgagc cagcaggcag cggaaattac cgtcagccat gtgcttattc
     9781 agatgctcgc catgccacgc agtgacctgc gggttattac ccgccagggc gatattggca
     9841 tggaagagtt gcgccaggcg ctgacggtgg agaactacac aaccgcccgt tctgcggaca
     9901 gctacccggc gttttccccg atgctggttg agtggctgaa agagggctgg ctgctggcgt
     9961 cggttgagat gcagcacagc gaactgcgcg gcggcgtgtt gctgctggcc ctgctgcatt
    10021 cgccgctgcg ttatataccg cctgctgccg cccggctgtt gaccggcatt aaccgtgacc
    10081 gtctgcaaca ggactttgtg cagtggacac aggagtcggc ggaatcagtc gttccggatg
    10141 cagacggtaa aggcgcaggc acactgacgg acgctgctga caccctgctt gcccgctacg
    10201 ccaaaaacat gaccgaagat gcccgtaacg gcaggcttga cccggtactg tgccgcgacc
    10261 acgaaatcga cctgatgatc gacattctct gccgccgccg taaaaacaat ccggtggtgg
    10321 tgggcgaagc aggcgtgggt aaaagcgcgc tgattgaagg gctggcgctg cgcatcgtgg
    10381 caggccaggt gccggacaaa ctgaaaaaca ccgatatcat gacccttgac ctgggcgcat
    10441 tgcaggccgg ggcatcggtg aagggcgagt ttgaaaaacg cttcaagggg ctgatggcgg
    10501 aggtcatttc ctccccggta ccggtcattc tgtttatcga cgaagcgca
//
LOCUS       DADXDL010000126        10466 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.126, whole genome shotgun sequence.
ACCESSION   DADXDL010000126 DADXDL010000000
VERSION     DADXDL010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10466)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10466)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10466
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.126"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1805
                     /locus_tag="IRB70_004328"
     CDS             <1..1805
                     /locus_tag="IRB70_004328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBC0634169.1"
                     /translation="PALARGELKTIAATTWSEYKKYFEKDAALSRRFQLVKVSEPNAA
                     EATIILRGLSAVYEQSHGVLIDDDALQAAATLSERYLSGRQLPDKAIDVLDTACARVA
                     INLSSPPKQISALTTLSHQQEAEIRQLERELRIGLRTDTSRMTEVLVQYDETLTALDE
                     LEAAWHQQQTLVQEIIALRQQLLGMAEDDAASLPDADAAEDTPSEAEQDNTDAEPADE
                     AGSEQPEETAETVSPVQRLAQLTAELDALHNDRLQVSPHVDKKQIAAVIAEWTGVPLN
                     RLSQNEMSVITDLPKWLGDTIKGQDLAIASLHKHLLTARADLRRPGRPLGAFLLAGPS
                     GVGKTETVLQLAELLYGGRQYLTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTEA
                     IRQKPYSVVLLDEVEKAHPDVLNLFYQAFDKGEMADGEGRLIDCKNIVFFLTSNLGYQ
                     VIVEHADDPETMQEALYPVLADFFKPALLARMEVVPYLPLSKETLATIIAGKLTRLDN
                     VLRSRFGAEVIIEPEVTDEIMSRVTRAENGARMLESVIDGDMLPPLSLLLLQKMAANT
                     AIARIRLSAADGTFTADVEDALDDESVTEDETVL"
     gene            1802..2545
                     /gene="tagO"
                     /locus_tag="IRB70_004329"
     CDS             1802..2545
                     /gene="tagO"
                     /locus_tag="IRB70_004329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system-associated protein
                     TagO"
                     /protein_id="HBC0634170.1"
                     /translation="MSRLRVFRQTGWFIAGLMAGLPASAAPAETSSMAGVAVAVATAT
                     PPDATATLQAMQSCRREFAALERLDCYDRLLEPLSPSGFDGALVKASFVGEAWTRAIE
                     QEKRRQGNTTELLVTQVPGERPTVVVTTPAIGHVPPRPVLMFSCVDNITRMQVALVHP
                     LDVHDIAVTLNADSRVLRSHWFVRENGTLLESSRGLSGIDEIKQLFGATTLTVDTGAD
                     NAAGKLTFNIDGLARVIAPLRDACHWAGE"
     gene            2550..3965
                     /gene="tssA"
                     /locus_tag="IRB70_004330"
     CDS             2550..3965
                     /gene="tssA"
                     /locus_tag="IRB70_004330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system protein TssA"
                     /protein_id="HBC0634171.1"
                     /translation="MAMDLRDPNVWISHLLENLPEEKQASALKDDNPDWEYIDGEIVK
                     LGSLAHSQLDIPELQRRGLVILASESKDFRLLAHLLRTLQHAGDPLLALRLLALYVEH
                     YWAVAAPQNMAHKKRFASQVIKRFETGIEGFSQNAATAQRDALLGELAKLAQCWQSHN
                     VPELAQATDDLFALYQRTFNRAAPAPVPTPAASGSSPQTTVTSESSMTQTSAPALQIA
                     IDSHDDKAWRDTLLKVAAILCERQPDSPLGYRLRRHALWQSITSTPQAESDGRTPLAA
                     VSADMVADYHAQLGSADMALWQQVEKSVLLAPYWLDGHCISAQTAHRLGYTAVADAIR
                     DEVVSFLGRLPALADLLFNDHTPFVSEKTKQWLATQPGNQAAPVIQVSNEDIQAARLC
                     FDEQGLEAALRYLDTLPAGEPRDQFHRQYLAAQLTEEAGLIQLAQQQYRMLFRMGLQM
                     MVADWEPSLLEQLEQKFTAEQ"
     gene            4074..7508
                     /gene="tssM"
                     /locus_tag="IRB70_004331"
     CDS             4074..7508
                     /gene="tssM"
                     /locus_tag="IRB70_004331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308245.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system membrane subunit TssM"
                     /protein_id="HBC0634172.1"
                     /translation="MLILAWIFLLVWIWWKGPTWTLYEEQWLKPLANRWLATAAWGII
                     ALVWLTVRVMKRLQQLEKMQKQQREEAVDALSVELNAQQRYLDRWLLRLQRHLDNRRF
                     LWQLPWYMVIGPVGSGKTTLLREGFPSDIIYAPEGARGAEQRLYLTPHVGKQAVIFDI
                     DGTLCAPADADILHRRLWEHALGWLKEKRARQPLNGIILTLDLPDLLTADKRRREHLL
                     QTLRSRLQDIRQHLHCQLPVYVVLTRLDLLQGFAALFQSLNRQDRDAILGVTFTRRAH
                     ENDDWRTELNAFWQTWVDRMNLALPDLMVTQTHTRASLFSFSRQMQGSREPLVSLLEG
                     LLDGENMNVMLRGVYLTSSLQRGQMDDIFTQSAARQYRLGNNPLASWPLVDTAPYFTR
                     SLFPQALLAEPNLATESSAWLMRSRRRLTVFSATGGVAALLLITGWHHYYNGNYQSGI
                     TVLKQAKAFMDVPPPQGEDDFGNLQLPLLNPVRDATLAYGDWGERSRLADMGLYQGRR
                     IGPYVEQTYLQLLEQRYLPSLFNGLVKAMNAAPPESEEKLAVLRVMRMLEDKSGRNNE
                     VVKQYMAKRWSEKFHGQRDIQTQLMSHLDYALAHTDWHAERQAGDGDAISRWTPYDKP
                     VVSAQKELSKLPVYQRVYQSLKTRALGVLPADLNLRDQVGPTFDQVFTSADDNKLVVP
                     QFLTRYGLQSYFVKQRDELVELTAMDSWVLNLTRSVKYSDADRAEIQRQLTEQYISDY
                     TATWRAGMDNLNIRNFESIGQLTGTLEQVISGDQPLQRALTVLRDNTQPGVFSEKLSA
                     KERDEALAEPDYQLLTRLGHEFAPENSTLTVQKDKESTMQAVYQQLTELHRYLLAIQN
                     APVPGKSALKAVQLRLDQNSSDPIFATRQMAKTLPAPLNRWVGRLADQAWHVVMVEAV
                     HYMEVDWRDSVVKPFNEQLANNYPFNPRSAQDASLDAFERFFKPDGILDTFYQQNLKL
                     FIDNDLSLEDGDNSVIIREDIIAQLETAQKIRDIFFSKQNGLGTSFAVETVSLSGNKR
                     RSVLNLDGQLVDYSQGRNYTAHLVWPNNMREGNESKLTLVGASGGAPRSISFSGPWAQ
                     FRLFGAGQLTGVQDGNFTVRFSVDGGAMTYRVHTDTEDNPFSGGLFSQFGLSDTLY"
     gene            7519..8871
                     /locus_tag="IRB70_004332"
     CDS             7519..8871
                     /locus_tag="IRB70_004332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001087757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system ImpA family N-terminal
                     domain-containing protein"
                     /protein_id="HBC0634173.1"
                     /translation="MNSNVLTQTIVTGSDPRGLPEFSAIREEINKASHPSQPELNWKL
                     VESLALAIFKANGVDLHTATYYTLARTRTQGLAGFCEGAELLAAMVSHDWDKFWPQGG
                     PARTEMLDWFNSRTGNILRQQISFAESDLPLIYRTERALQLICDKLQQVELKRVPRVE
                     NLLYFMQNTRKRLEPQPKSNAENTSQTTVRTLIYAPETMASSTPEAVVPPLPDLPEMK
                     VEVRSLSENPPQASVMKQGSTVRGFIAGIVCSVAVASALWWWQVYPVQQQLLQVNDTA
                     QGAATVWMASPELENYERRLQQLLGVSPVQPLETGMQMMRVADSRWPESLQQQQASTQ
                     WNEALKTRAQSSPQLRGWLQTRQDLHAFADLVMQREKEGLTLSYIKNVIWQAERGLGQ
                     ETPVESLLTQYQDARAQKQNTDALEKQINERLEGVLSRWLLLKNNIMPEAATGTTAKK
                     "
     gene            8895..9377
                     /locus_tag="IRB70_004333"
     CDS             8895..9377
                     /locus_tag="IRB70_004333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HBC0634174.1"
                     /translation="MANMSYLSLSGETQGLISAGCSTLDSVGNKAQPGHKDQIMVYAL
                     MHSISRSQNVNHHELIITKPVDKSSPLLAKALSDNEKMVTCEFILYRTSKAGIYQPYY
                     KINLSKARISSIDFVTPHAVLEKELEPQERIAFIYEDISWEHTLAGTNAMSKWQDRVQ
                     "
     gene            9421..10329
                     /locus_tag="IRB70_004334"
     CDS             9421..10329
                     /locus_tag="IRB70_004334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016159327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634175.1"
                     /translation="MAGLRNNSNTQNAQWADYVGDILRGAQPINQLVPQHPYLNDIPL
                     IDELRRQNTHHVILLTFDVAKKILSSITSFDYIHFITTHPSGIKDTLAWLVNAGKLMT
                     EFDENGKIIFNLNALKYTKASYFEILGEKYIKITTSSPWLLEKLGKYIFSSRAPQVLE
                     LAIGWRGALSESIKGVKFCIWFSVAWRTIEFITSSERDLVNFLGDFSMDVAKAVIAGG
                     VATAIGSLASFACLSFGLPVILVGGAILLTGIVCTVVLNEIDVQYHLSEKLKDAIRDG
                     LKRQQELDKWKRENMTPFMYVLNTPL"
BASE COUNT         2541 a         2785 c         2891 g         2249 t
ORIGIN      
        1 aaccggcgct ggcgcgcggc gagctgaaaa ccatcgccgc caccacctgg agcgagtaca
       61 aaaaatactt cgagaaagat gcagctttgt cacgccgctt tcagttagtg aaggtcagcg
      121 aacccaacgc cgccgaagcc accattattc tgcgcggtct gtcggcggtc tatgaacagt
      181 ctcatggcgt gctgattgat gatgacgcct tgcaggccgc agcgacatta agcgagcgtt
      241 atctctccgg gcgtcagctg ccggacaaag ccattgatgt gctggatact gcctgcgccc
      301 gcgtggccat taacctttca tcgccaccga agcaaatctc ggcgctgacc accctgagcc
      361 accagcagga ggcggaaatt cgccagcttg agcgcgagct tcgcatcggg ctgcgtaccg
      421 acacctcacg gatgacggag gtgctggtgc agtatgatga aacgctgacg gcgctggacg
      481 aactggaagc cgcctggcat cagcaacaga cgctggtaca ggaaattatc gcgctgcgcc
      541 agcagttact gggtatggca gaagacgatg cggcgtcgtt gccggacgca gatgccgcgg
      601 aggatacgcc gtctgaggca gaacaggata ataccgatgc cgaaccggct gatgaagctg
      661 gcagcgaaca gccggaagag accgctgaaa cagtttcccc ggtacaacgg ctggcacagc
      721 ttactgccga actggacgcc ctgcataacg accggttgca ggtctccccg cacgtcgata
      781 aaaaacagat tgcggcggtg attgccgaat ggactggcgt tccgcttaac cgcctgtcgc
      841 agaatgaaat gtcggtcatc accgacctgc cgaaatggct gggcgacacc atcaaaggcc
      901 aggatctggc gattgccagc ctgcataagc atctgctgac tgcacgcgcc gacctgcgcc
      961 gcccgggacg cccgctcggc gcgttcctgc tggctggccc cagcggcgtg ggtaaaaccg
     1021 aaaccgttct gcaactggca gaactgctct acggcggtcg ccagtacctg accaccatta
     1081 atatgtccga gttccaggag aaacacaccg tttcacgcct gattggttcg cctccgggct
     1141 acgttggcta tggcgaaggc ggcgtgctga ccgaagcgat tcgccagaaa ccgtactcgg
     1201 tggtgctact cgatgaagtg gaaaaagcgc acccggatgt cctcaacctg ttctaccagg
     1261 cgtttgacaa gggcgagatg gcagacggcg aaggtcgcct gattgactgt aaaaacatcg
     1321 tcttcttcct cacctccaac cttggctacc aggtgattgt cgaacacgcc gatgacccgg
     1381 agaccatgca ggaagccctc tatccggtgc tggcggactt ctttaaacct gccctgctgg
     1441 cgcgtatgga agtggtgccg tacctgccgt tgtcgaaaga gacgctcgcc accattattg
     1501 ccgggaaact cacccgtctg gataacgtgc tgcgcagtcg ctttggcgcg gaagtgatta
     1561 ttgagccgga agtgacggac gaaatcatga gccgcgtcac ccgagcggaa aacggcgcga
     1621 ggatgctcga atcggtcatt gacggcgaca tgctgccgcc gctctccctg ctgctgttgc
     1681 agaagatggc agccaacacg gcgattgccc ggattcggct gtcggcggca gacggcacgt
     1741 tcacagcaga tgtggaagat gctctggacg acgagtccgt cacagaagat gaaacggttt
     1801 tatgagcagg ttgcgcgttt tccggcagac aggatggttt attgcgggcc tgatggcggg
     1861 cttacccgcc agtgccgcgc ccgcagaaac atcgtcaatg gccggtgtgg cggtagccgt
     1921 cgccacagcg accccgccgg atgcgacagc cacattacag gccatgcagt cctgtcggcg
     1981 ggagttcgcg gcgctggagc ggcttgactg ctatgaccgc ctgctggaac cgctgtcccc
     2041 gtcagggttt gacggggcgc tggtcaaagc cagttttgtg ggcgaagcct ggacccgtgc
     2101 catagagcag gaaaaacgtc gccagggcaa caccacagag ctgctggtga cgcaggtgcc
     2161 gggggaacgc ccgacggtgg tggtaaccac cccggctatc ggccatgttc cgcctcgccc
     2221 ggtgctgatg ttcagctgtg tggacaatat cacccggatg caggtggcgc tggtgcaccc
     2281 tctggatgtc catgatatcg ccgtcaccct gaatgccgac agccgggtat tgcgcagcca
     2341 ctggtttgtg cgcgagaacg gcaccctgct ggagtccagc cgggggctgt ccgggattga
     2401 tgaaattaag cagctgttcg gcgcaacaac gctgacggtg gataccggcg cagacaacgc
     2461 agccggaaag ctgaccttta acattgacgg gctggcacgg gttattgcgc cgctacgcga
     2521 cgcctgccac tgggcgggag aataaaaata tggcaatgga cttacgcgat ccgaatgtct
     2581 ggatatcgca cctgctggaa aacctgcctg aagaaaaaca ggcatcggcg ctaaaagatg
     2641 acaacccgga ctgggagtat atcgacggcg aaatcgtcaa actgggttca ctggcccaca
     2701 gccaactgga tatcccggaa ctccagcgcc gggggctggt cattctggct tcggagagta
     2761 aggattttcg tctgctggcg catctgctga gaaccctgca acatgccggt gatccgcttc
     2821 tggccttgcg cctgctggca ctgtatgtgg aacattactg ggcggtggcc gcgccgcaga
     2881 atatggcaca taaaaaacgc ttcgccagcc aggtcattaa acgctttgaa acaggtattg
     2941 aaggcttttc acagaacgcc gccacagcgc agcgcgatgc gctattaggt gaactggcga
     3001 aactggcgca gtgctggcag tcacataacg tcccggaact ggcacaggct accgatgatc
     3061 tttttgccct gtaccagcgt acgtttaatc gtgcggctcc tgctccggtc cccactccgg
     3121 cggcctccgg tagttcacca caaaccaccg tcacgtctga aagcagcatg acgcaaacca
     3181 gtgctccggc tctacagatc gccatcgaca gtcacgacga caaagcctgg cgcgacacgc
     3241 tgttaaaagt ggcggctatt ttatgtgaac gccagccgga ctcgccgctg ggctatcgcc
     3301 tgcgccgcca tgccctgtgg caatccatca ccagtacgcc ccaggcggaa agcgatggac
     3361 gtaccccact ggctgcggtc tctgccgata tggtggcgga ttaccatgct cagctcggta
     3421 gtgccgatat ggcgctgtgg cagcaggtgg aaaaaagcgt attgctggca ccctactggc
     3481 tggacggtca ctgcatttct gcacagacgg cgcaccgtct tggctatacc gccgtggccg
     3541 atgccatccg cgatgaagtc gtttccttcc ttggccgtct gcccgctctt gccgatcttc
     3601 tgtttaacga ccacacaccg tttgtttctg aaaaaacgaa gcaatggctt gcaactcagc
     3661 caggtaacca ggccgcgcca gtcatacagg tgagtaatga agatattcag gctgcgcggt
     3721 tgtgttttga tgaacagggg ctggaagccg ccttacggta tctggatacg ttgcccgccg
     3781 gtgaaccccg cgatcagttt caccgccagt accttgccgc acagttgacg gaggaggcgg
     3841 ggctgataca gcttgcgcag caacagtacc ggatgttgtt caggatggga ttgcagatga
     3901 tggtggcaga ctgggagccg tccctgcttg agcagctaga acaaaaattc acggcagaac
     3961 aataaaagag aacaggagtt tttgtgttca gattaccaac accccgacta ttcagcggac
     4021 tcaaatcagc cctgcgcccg gcgatgcccc ggtttaaagt ttctgcattc tggctgctga
     4081 tactggcgtg gattttcctg ctggtatgga tctggtggaa aggcccgaca tggacgctgt
     4141 atgaagagca gtggctcaaa ccactggcga accgctggct ggcaacggcg gcgtggggga
     4201 ttattgccct ggtgtggctt accgtccggg taatgaagcg cctgcaacag cttgaaaaaa
     4261 tgcaaaagca acagcgcgag gaagccgttg atgcgctcag tgtggaactg aacgcccagc
     4321 agcgttacct cgaccgctgg ctgctgcgcc tgcaacgcca tctcgacaac cgccgtttcc
     4381 tgtggcagtt gccgtggtat atggtcatcg gtcctgtggg cagtggcaaa acgacactgc
     4441 tgcgcgaggg gtttccgtca gacattattt atgccccgga gggcgcgcgc ggcgcagaac
     4501 aacgcctgta cctcacgccc catgtcggta aacaggcggt gatctttgat atcgacggca
     4561 cactctgcgc tcccgctgat gcggatatcc tgcatcgccg tctgtgggaa catgccctcg
     4621 gctggctgaa ggaaaagcgc gcgcgccagc cgctgaacgg gattattctg acactcgatt
     4681 tacccgatct gctgaccgca gacaaacgcc gccgcgagca tctgttacag acgctgcgca
     4741 gccgcttaca ggatatacgc cagcatcttc attgccagtt accggtttac gtggtactga
     4801 cccggcttga tttattgcag ggttttgccg ccctgtttca gtcactgaac agacaggatc
     4861 gcgatgcgat tctgggtgtt acgttcaccc gccgtgctca tgaaaatgat gactggcgaa
     4921 cagagttgaa tgctttctgg cagacatggg tggatcgaat gaatctggcg ttgccggatc
     4981 tgatggtcac ccagactcac acccgcgcgt ctttattcag tttttcccgc cagatgcagg
     5041 gaagccgtga gccgctggtg tcactgcttg agggtctgct tgacggcgaa aatatgaacg
     5101 tgatgctgcg tggtgtctat ctcacctctt cgcttcagcg tggacagatg gatgatatat
     5161 tcacccagtc tgctgcccgc cagtaccgac tgggcaataa cccactggcg tcctggcctc
     5221 tggtggacac cgcgccttat ttcacccgca gcctgttccc gcaggcatta ctcgcagagc
     5281 ctaatctggc aacagagagc agcgcctggc tgatgcgttc ccgtcgccgc ctgacggttt
     5341 tctctgccac aggcggcgtg gcggcactgc ttctcatcac cggctggcat cactattaca
     5401 acggtaacta tcagtccggc atcaccgtgc ttaagcaggc caaagccttt atggacgtgc
     5461 cgcctccgca gggggaagat gactttggca acctgcaact gccactgctg aacccggtac
     5521 gcgatgcaac actggcctat ggcgactggg gcgagcgcag ccgtctggcc gatatgggcc
     5581 tgtaccaggg gagacgtatc gggccatatg tggaacagac ctatctgcaa cttctggagc
     5641 agcgttacct gccctcgctg tttaacgggc tggtcaaagc gatgaatgcc gcgccgccgg
     5701 agagtgaaga aaaactcgcg gtgctgcgcg tgatgcgaat gctggaggac aaaagcggac
     5761 gtaacaatga ggtggtgaag cagtatatgg caaaacgctg gagcgaaaag ttccacggac
     5821 agcgcgatat ccagacacaa ctgatgtccc atcttgacta cgcgctggct catactgact
     5881 ggcatgcaga gcgtcaggcg ggcgacggtg atgccatcag ccgctggacg ccatatgaca
     5941 agcccgtggt atcagcacag aaagaactga gcaaactgcc tgtctaccag cgggtttatc
     6001 agagcctgaa aacgcgggcg ctgggcgttc ttcctgctga cctcaatctg cgtgaccagg
     6061 tagggccaac ctttgaccag gtgtttacat ctgccgatga taacaaactg gttgttccac
     6121 agtttcttac ccgttacggc ctgcaaagct attttgtaaa acagcgcgat gaactggttg
     6181 aactgacggc gatggattcc tgggtactca acctcacccg cagcgtgaaa tacagtgacg
     6241 ccgaccgcgc ggaaattcag cgccagttga ccgagcagta tatcagcgac tacaccgcca
     6301 cctggcgggc cgggatggac aatctcaata tccgcaattt tgagtccatt ggacaactga
     6361 ctggcactct ggagcaggtt atcagcggcg accagccttt gcagcgggcg ctgaccgtgc
     6421 tgcgtgacaa cacacagcca ggagtctttt ctgaaaaact ctctgccaaa gagcgggatg
     6481 aggccctggc agagccggat taccagttac ttacccgcct cgggcatgaa ttcgccccgg
     6541 aaaacagtac cctgacagta cagaaagaca aagaaagcac gatgcaggcc gtataccagc
     6601 agctcaccga gttacaccgc tacctgctgg caatccagaa cgcgcctgta ccagggaaat
     6661 cggcgctgaa agccgtgcag ttaaggcttg atcagaacag cagcgatcca atattcgcca
     6721 cccgccagat ggcaaaaaca ctgcctgctc cgctcaaccg ctgggtaggc aggctggctg
     6781 accaggcctg gcatgtggtg atggtggaag ccgttcacta tatggaagtg gactggcgcg
     6841 acagcgtggt gaaaccgttt aacgagcaac tggcaaataa ctatccgttt aatccacgtt
     6901 ctgcacagga tgcctcactg gatgccttcg aacgattctt taaaccggat ggcatactgg
     6961 ataccttcta ccagcagaac ctgaaactgt ttatcgacaa tgatctgagc ctggaagacg
     7021 gcgataacag cgtcattatc cgcgaagata ttattgcgca actggaaacc gcgcagaaaa
     7081 tccgtgacat cttcttcagc aaacagaacg gtctgggaac atcctttgcc gtggaaacgg
     7141 tatcgctttc cggcaacaaa cgccgcagcg tactgaacct tgacggccag ttagtcgatt
     7201 acagccaggg ccgtaactat accgcccatc tggtctggcc taacaatatg cgcgaaggca
     7261 acgaaagcaa actgacgctg gttggtgcca gcggcggcgc accgcgcagt atcagcttca
     7321 gcgggccgtg ggcacagttc cgcctgttcg gggccggaca actgaccgga gtacaggatg
     7381 gcaactttac cgtgcgcttt agcgtggacg gtggcgcgat gacctaccgt gtgcataccg
     7441 acaccgagga taacccgttc agcggtgggt tgttcagcca gtttggtctg tcagacacac
     7501 tgtactgagg aggcagggat gaatagtaac gtactgacac aaactatcgt taccggcagt
     7561 gacccgcgcg ggctgccgga attcagcgcc atccgcgagg aaataaacaa agccagccac
     7621 ccgtcacagc ctgagctgaa ctggaaactg gtggagtcgc tggcgctggc gatttttaaa
     7681 gctaacggtg tggatttaca caccgccacc tactatacgc ttgcacggac acggacacag
     7741 ggactggcgg gcttttgcga aggtgcggaa ctgctggcgg caatggtaag ccacgactgg
     7801 gataagttct ggccgcaggg cggcccggcg cgtactgaaa tgctggactg gtttaactcc
     7861 cgaaccggca atattctgcg tcagcaaatc tcctttgcgg aatccgacct accactgatc
     7921 taccgcacgg agcgggcatt gcagcttatc tgcgacaaac tccagcaggt agagctgaag
     7981 cgcgttccgc gcgtggagaa tctgctctat tttatgcaga acacgcgtaa acggcttgaa
     8041 ccccagccga agagtaacgc cgagaacacc tcacagacta cggtcagaac gctgatttat
     8101 gccccggaaa caatggcttc ctccacgcca gaagcggtag tgcctcccct gcccgacctg
     8161 cctgagatga aagtggaagt gcgcagtctg tcagaaaatc ccccacaggc cagtgtgatg
     8221 aagcaaggca gtacggtaag agggtttatc gcagggatcg tctgttcagt ggctgtcgcc
     8281 tcagcattgt ggtggtggca ggtctatccg gtgcagcagc aactgttaca ggttaacgac
     8341 accgctcagg gcgcagcaac ggtgtggatg gcctcacctg aactcgaaaa ctatgagcgc
     8401 aggctgcaac agcttcttgg cgtctccccg gtacaaccgc tggaaaccgg aatgcagatg
     8461 atgcgtgttg ccgacagtcg ctggccggaa agcctgcaac agcagcaggc ctcgacacaa
     8521 tggaatgagg cactcaaaac ccgcgcacag agtagcccac agttgcgtgg ctggttacag
     8581 actcgtcagg acttacatgc ttttgcagat ctcgtgatgc agcgcgagaa agagggacta
     8641 accctttcct atatcaaaaa tgtcatctgg caggcggagc ggggactggg gcaggaaaca
     8701 cccgttgagt ctctgttgac gcagtaccag gatgcccgtg cgcagaagca gaatacagat
     8761 gcgctggaaa aacaaattaa tgagcgactc gaaggcgtgt taagccgctg gctgctgctg
     8821 aagaataaca tcatgccaga ggcggcaacc gggaccacgg ccaaaaaata attatttaat
     8881 taaaggagat tatcatggca aatatgagtt atttatcttt gagtggagag acgcaagggc
     8941 tgatttcagc aggttgctca acgcttgatt ctgtcggaaa caaagcgcaa ccaggacata
     9001 aagatcagat catggtttat gcgttaatgc attccatctc aagaagtcaa aatgtcaatc
     9061 atcatgaatt aattatcacc aaaccggttg ataaatcctc accattgctg gcaaaagcac
     9121 ttagtgacaa tgaaaaaatg gtaacatgtg aatttatact ctaccgaacc agtaaagcgg
     9181 gtatttacca gccttattat aaaataaatc tgtcaaaagc ccgaatatca agtattgatt
     9241 ttgtcacacc gcatgctgtc ttggaaaaag aactggagcc acaggagaga attgccttta
     9301 tttatgaaga tatttcctgg gagcatacgt tagccggtac gaatgcaatg agtaaatggc
     9361 aggatcgtgt acagtaactt actgtaataa aataataaat cactattacg gagagataaa
     9421 atggctggtt taaggaataa tagcaacaca cagaatgcac agtgggctga ttatgtgggt
     9481 gacattcttc ggggggctca gccgataaac cagctagtac ctcagcaccc ttatcttaac
     9541 gatatcccac tcattgatga gttaaggcgt cagaacactc atcatgttat tcttttgaca
     9601 tttgatgttg caaaaaaaat tctcagctca ataacatcat ttgattacat tcattttatc
     9661 actacacatc cttcaggtat aaaagataca ctcgcctggt tagttaacgc gggtaaatta
     9721 atgactgagt ttgatgaaaa tgggaaaatt atatttaacc ttaatgcctt aaagtataca
     9781 aaagcaagtt actttgaaat acttggagaa aaatatataa aaatcacaac atccagcccc
     9841 tggcttttag aaaagctcgg taaatatatt ttctcttcac gagctcctca agttctggaa
     9901 ctcgctattg gctggcgagg agctttatct gaatcaataa aaggagttaa gttctgtatc
     9961 tggttttcag tagcctggag aaccatagaa tttattacga gttcagagcg agatctggtt
    10021 aattttcttg gtgatttttc aatggatgtg gccaaagcag tgattgcagg cggtgttgca
    10081 accgctattg gaagcctggc ttcttttgcc tgtcttagtt ttggccttcc agtaattctt
    10141 gtaggaggag caattttact tacggggata gtgtgtacag ttgttttaaa tgaaatcgat
    10201 gttcaatacc atttatcaga aaaattaaaa gatgcaatta gagatggact aaaacggcaa
    10261 caggaacttg ataaatggaa aagggaaaac atgactccat ttatgtatgt tcttaacacc
    10321 cccctgtgat atgaggatta actatgcgtt tacatgttaa attgaaagag tttctttcga
    10381 tgttttttat agccatatta tttttccctg cattcaatgc atctttgttt tttaccggaa
    10441 ttaaacctct atattcaata ataaaa
//
LOCUS       DADXDL010000127        10458 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.127, whole genome shotgun sequence.
ACCESSION   DADXDL010000127 DADXDL010000000
VERSION     DADXDL010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10458)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10458)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10458
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.127"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..950)
                     /gene="adeQ"
                     /locus_tag="IRB70_004335"
                     /gene_synonym="yicO"
     CDS             complement(<1..950)
                     /gene="adeQ"
                     /locus_tag="IRB70_004335"
                     /gene_synonym="yicO"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine permease AdeQ"
                     /protein_id="HBC0634176.1"
                     /translation="MNNDNTDYVSNESGTLSRLFKLPQHGTTVRTELIAGMTTFLTMV
                     YIVFVNPQILGAAQMDPKVVFVTTCLIAGIGSIAMGIFANLPVALAPAMGLNAFFAFV
                     VVGAMGISWQTGMGAIFWGAVGLFLLTLFRIRYWMISNIPLSLRIGITSGIGLFIALM
                     GLKNTGVIVANKDTLVMIGDLSSHGVLLGILGFFIITVLSSRHFHAAVLVSIVVTSCC
                     GLFFGDVHFSGVYSIPPDISGVIGEVDLSGALSLELAGIIFSFMLINLFDSSGTLIGV
                     TDKAGLIDSNGKFPNMNKALYVDSVSSVAGAFIGTSSVTA"
     gene            1125..2891
                     /gene="adeD"
                     /locus_tag="IRB70_004336"
     CDS             1125..2891
                     /gene="adeD"
                     /locus_tag="IRB70_004336"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBC0634177.1"
                     /translation="MNNSINHKFHHISRAEYQELLAVSRGDAVADYIIDNVSILDLIN
                     GGEISGPIVIKGRYIAGVGAEYADAPALQRIDARGATAVPGFIDAHLHIESSMMTPVT
                     FETATLPRGLTTVICDPHEIVNVMGEAGFAWFARCAEQARQNQYLQVSSCVPALEGCD
                     VNGASFTLEQMLAWRDHPQVTGLAEMMDYPGVISGQNALLDKLDAFRHLTLDGHCPGL
                     GGKELNAYIAAGIENCHESYQLEEGRRKLQLGMSLMIREGSAARNLNALAPLINEFNS
                     PQCMLCTDDRNPWEIAHEGHIDALIRRLIEQHNVPLHVAYRVASWSTARHFGLNHLGL
                     LAPGKQADIVLLSDARKVTVQQVLVKGEPIDAQTLQAKESARLAQSAPPYGNTIARQP
                     VSASDFALQFTPGKRYRVIDVIHNELITHSRSSVYSENGFDRDDVCFIAVLERYGQRL
                     APACGLLGGFGLNEGALAATVSHDSHNIVVIGRSAEEMALAVNQVIQDGGGLCVVRNG
                     QVQSHLPLPIAGLMSTDTAQSLAEQIDALKAAARECGPLPDEPFIQMAFLSLPVIPAL
                     KLTSQGLFDGEKFAFTTLEFTE"
     gene            complement(2938..4329)
                     /gene="uhpT"
                     /locus_tag="IRB70_004337"
     CDS             complement(2938..4329)
                     /gene="uhpT"
                     /locus_tag="IRB70_004337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hexose-6-phosphate:phosphate antiporter"
                     /protein_id="HBC0634178.1"
                     /translation="MLAFLNQVRKPTLDLPLEVRRKMWFKPFMQSYLVVFIGYLTMYL
                     IRKNFNIAQNDMISTYGLSMTQLGMIGLGFSITYGVGKTLVSYYADGKNTKQFLPFML
                     ILSAICMLGFSASMGSGSVSLFLMIAFYALSGFFQSTGGSCSYSTITKWTPRRKRGTF
                     LGFWNISHNLGGAGAAGVALFGANYLFDGHVIGMFIFPSIIALIVGFIGLRYGSDSPE
                     SYGLGKAEELFGEEISEEDKETESTDMTKWQIFVEYVLKNKVIWLLCFANIFLYVVRI
                     GIDQWSTVYAFQELKLSKAVAIQGFTLFEAGALVGTLLWGWLSDLANGRRGLVACIAL
                     ALIIATLGVYQHASNEYIYLASLFALGFLVFGPQLLIGVAAVGFVPKKAIGAADGIKG
                     TFAYLIGDSFAKLGLGMIADGTPVFGLTGWAGTFAALDIAAIGCICLMAIVAVMEERK
                     IRREKKIQQLTVA"
     gene            complement(4467..5786)
                     /gene="uhpC"
                     /locus_tag="IRB70_004338"
     CDS             complement(4467..5786)
                     /gene="uhpC"
                     /locus_tag="IRB70_004338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312631.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter family glucose-6-phosphate
                     receptor UhpC"
                     /protein_id="HBC0634179.1"
                     /translation="MLPFLKAPADAPLMTDKHEIDARYRYWRRHILLTIWLGYALFYF
                     TRKSFNAAVPEILANGVLSRSDIGLLATLFYITYGVSKFVSGIVSDRSNARYFMGIGL
                     IATGIINILFGFSTSLWAFAVLWVLNAFFQGWGSPVCARLLTAWYSRTERGGWWALWN
                     TAHNVGGALIPIVMAAAALHYGWRAGMMIAGCMAIVVGIFLCWRLRDRPQALGLPAVG
                     EWRHDALEIAQQQEGAGLTRKEILTKYVLLNPYIWLLSFCYVLVYVVRAAINDWGNLY
                     MSETLGVDLVTANTAVTMFELGGFIGALVAGWGSDKLFNGNRGPMNLIFAAGILLSVG
                     SLWLMPFASYVMQATCFFTIGFFVFGPQMLIGMAAAECSHKEAAGAATGFVGLFAYLG
                     ASLAGWPLAKVLDTWHWSGFFVVIAIAAGISALLLLPFLNAQTPREA"
     gene            complement(5796..7298)
                     /gene="uhpB"
                     /locus_tag="IRB70_004339"
     CDS             complement(5796..7298)
                     /gene="uhpB"
                     /locus_tag="IRB70_004339"
                     /EC_number="2.7.13.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312632.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal transduction histidine-protein
                     kinase/phosphatase UhpB"
                     /protein_id="HBC0634180.1"
                     /translation="MKTFFSRLITVIACFFIFSAAWFCLWSISLHLVERPDMAVLLFP
                     FGLRLGLMLQCPRGYWPVLLGAEWLLIYWLMQAVGLTHFSLLMIGSLLTLLPVALISR
                     YRHQRDWRTLLLQGAALTAAALLQSLPWLWHGKESWNALLLTLTGGLTLAPICLVFWH
                     YLANNIWLPLGPSLVSQPINWRGRHLVWYLLLFVISLWLQLGLPDELSRFTPFCLALP
                     IIALAWHYGWQGALIATLMNAIALIASQTWRDHSVDLLLSLLVQSLTGLLLGAGIQRL
                     RELNQSLQKELARNQHLAERLLETEESVRRDVARELHDDIGQTITAIRTQAGIVQRLA
                     ADNASVKQSGQLIEQLSLGVYDAVRRLLGRLRPRQLDDLTLEQAIRSLMREMELEGRG
                     IVSHLEWRIDESALSENQRVTLFRVCQEGLNNIVKHADASAVTLQGWQQDERLMLVIE
                     DDGSGLPPGSGQQGFGLTGMRERVTALGGTLTISCLHGTRVSVSLPQRYV"
     gene            complement(7298..7888)
                     /gene="uhpA"
                     /locus_tag="IRB70_004340"
     CDS             complement(7298..7888)
                     /gene="uhpA"
                     /locus_tag="IRB70_004340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator UhpA"
                     /protein_id="HBC0634181.1"
                     /translation="MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLP
                     GRGVQVCICDISMPDISGLELLSQLPKGMATIMLSVHDSPALVEQALNAGARGFLSKR
                     CSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
                     ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW"
     gene            complement(8050..9488)
                     /locus_tag="IRB70_004341"
                     /pseudo
     CDS             complement(8050..9488)
                     /locus_tag="IRB70_004341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(9767..10249)
                     /locus_tag="IRB70_004342"
     CDS             complement(9767..10249)
                     /locus_tag="IRB70_004342"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634182.1"
                     /translation="MVELVYFNDNDCARVRELLKKSNGNIADDKIDEIIACLSSHQGI
                     TCFYYSSVQGYQSYLKNTSQDVSELLSKSLDDAISSTSGLKNSGNTFFGTGKYLKEMD
                     FTINGFSQKMYLMAVNNVGNEVKLQCSRYFTTGRVDKENSKIDKVAFTFFGAATTADL
                     "
BASE COUNT         2880 a         2751 c         2362 g         2465 t
ORIGIN      
        1 taggcggtaa cagacgaggt accgataaac gcacccgcca ccgaactgac gctatcaaca
       61 tacagcgcct tattcatatt ggggaattta ccgttactat ctattaagcc agctttatca
      121 gttacaccaa ttaatgttcc tgatgaatca aataagttga tcagcataaa ggagaaaatg
      181 ataccggcga gttcaagtga taacgcgccg ctcaaatcca cttcaccaat gacgccgcta
      241 atatcaggcg gaatggaata gacgccgcta aaatgaacat caccgaaaaa taatccacag
      301 caagacgtca ccacaataga aacaagcacc gcggcatgaa aatgacgtga tgacaacacg
      361 gttataataa aaaaccctaa aatacctaac aacacgccgt gagaacttaa atcgccaatc
      421 atcaccaggg tgtctttatt ggcgacaata acgccagtat tttttaatcc cattaaggcg
      481 ataaataatc cgattccgct ggtgatacca atacgtaaac ttaatggaat gttggagatc
      541 atccagtacc ggatacgaaa cagcgtgagc aaaaatagcc caactgcgcc ccagaatatc
      601 gcgcccatcc cggtctgcca ggagataccc atcgccccca cgaccacgaa cgcaaagaag
      661 gcgttcagcc ccattgccgg agccagcgcc acgggtaagt tagcaaatat ccccatcgca
      721 atactgccga taccggcaat caaacaggtg gtaacaaaca ccactttcgg gtccatttgt
      781 gccgcgccga ggatttgcgg gttcacaaaa acgatgtaca ccatggttaa aaaagtggtc
      841 atccccgcaa tcaattctgt gcggacggtg gtcccatgct gaggtagttt aaataatcgc
      901 gaaagcgtcc ctgattcatt actcacgtaa tcggtattgt cattattcat ttttttgtcc
      961 attggaggag atttaatccc ttgcttttgt aaaacaaatg acaacaacgg ttcagtgata
     1021 attatcacat ttcaattgca cattaatgga tattctttaa taatctcgcg acgtttcttt
     1081 atgataaata ataatcaaat tgataaaatc aaaatgagaa aaatatgaat aattctatta
     1141 accataaatt tcatcacatt agccgggctg aataccagga attgttagcc gtttcccgtg
     1201 gagacgctgt tgccgattat attattgata atgtctctat tctcgacctg atcaatggcg
     1261 gagaaatttc cggcccaatt gtgattaaag gacgttacat tgccggtgtt ggcgcagaat
     1321 acgctgatgc tccggcgttg cagcggattg atgcccgcgg cgcaacggcg gtgccagggt
     1381 ttattgatgc tcacctgcat attgaatcca gcatgatgac gccggtcact tttgaaaccg
     1441 cgaccctgcc gcgcggcctg acgaccgtta tttgcgaccc tcatgaaatc gtcaacgtga
     1501 tgggcgaagc cggattcgcc tggtttgccc gctgtgccga acaggcaagg caaaaccagt
     1561 acttacaggt cagctcttgc gtacccgctc tggaaggctg cgatgttaac ggtgccagtt
     1621 ttacccttga acagatgctc gcctggcggg accatccgca ggttaccggc cttgcagaaa
     1681 tgatggacta ccctggcgta attagcgggc agaatgcgct gctcgataaa ctggatgcat
     1741 ttcgccacct gacgctggac ggtcactgcc cgggtttggg tggtaaagaa cttaacgcct
     1801 atattgctgc gggtattgaa aactgccacg aaagttatca gctggaagaa ggacgccgga
     1861 aattgcaact cggcatgtcg ttgatgatcc gtgaagggtc cgcagcccgc aatctcaacg
     1921 cgctggcacc gttgatcaac gaatttaaca gcccgcaatg catgctctgt accgatgacc
     1981 gtaacccgtg ggagatcgcc catgaaggac acatcgatgc cttaattcgc cgcctgatcg
     2041 aacaacacaa tgtaccgctg catgtggcat atcgcgtagc cagctggtcg acggcgcgcc
     2101 attttggtct gaatcacctc ggcttactgg cacccggcaa gcaggccgat atcgtcctgt
     2161 tgagcgatgc gcgtaaggtc acggtgcagc aggtactggt gaaaggcgag ccgatcgatg
     2221 cgcaaacctt acaggcgaaa gagtcggcga gactggcaca atccgctccg ccgtatggca
     2281 ataccattgc ccgccagcct gtttccgcca gcgactttgc cctgcaattc acgcccggaa
     2341 aacgctatcg ggtcattgac gtcatccata acgaattgat tacccactcc cgctccagcg
     2401 tctacagcga aaacggtttt gatcgcgatg atgtgtgctt tattgccgtt cttgagcgtt
     2461 acggacaacg actggctccg gcctgtggtt tactcggcgg ctttggcctg aatgaaggtg
     2521 cgctggcggc gacggtcagc catgacagcc ataatattgt ggtgataggt cgtagcgcag
     2581 aagagatggc gctggcggtc aatcaggtga ttcaggatgg cggcgggctg tgcgtggtcc
     2641 gtaacggtca ggtacaaagt catctaccgt tgcccattgc cgggctaatg agcaccgaca
     2701 cggcgcagtc actggcggag caaattgacg ccttgaaagc cgccgcccgt gaatgcggtc
     2761 cgttacccga tgagccgttt attcagatgg cgtttctttc cctgccagtg atccccgcgc
     2821 tgaaactaac cagtcagggg ctgtttgatg gcgagaagtt tgccttcact acgctggaat
     2881 tcacggaata ataaaaaaaa gcccggcgtc atgccgggca aaagtcacca gttacgttta
     2941 tgccactgtc aactgctgaa tttttttctc gcggcggatt ttgcgttctt ccatcaccgc
     3001 cactatcgcc atcaggcaga tacaaccaat cgcggcgata tccagcgcgg cgaaggtgcc
     3061 tgcccagccg gtaaggccaa ataccggcgt cccatcggca atcattccca gacctaactt
     3121 ggcaaagctg tcaccaatca ggtaagcgaa ggtgccttta ataccatcgg cagcgccaat
     3181 cgctttttta ggtacaaagc caacagcagc tacaccaatc aacaattgcg ggccaaagac
     3241 caggaaaccc aacgcaaaga gagaagcaag gtagatatat tcgttgctgg cgtgttgata
     3301 cacaccgagc gtggcgataa tcagcgccag cgcgatacag gccaccaggc cacggcgacc
     3361 gttcgccagg tcagagagcc agccccacag cagcgtaccg accagcgcac cagcttcaaa
     3421 cagcgtaaag ccctgaatcg ccaccgcttt agagagtttc agttcctgga acgcatacac
     3481 ggttgaccac tggtcgatac caatacgcac cacatagagg aaaatgttgg caaagcacag
     3541 cagccagatc actttgtttt tcagcacata ctcaacaaag atctgccact tggtcatatc
     3601 ggtagattct gtctctttat cctcttcact gatctcctcg ccaaacagct cttcagcttt
     3661 gccgaggcca taagattccg gggagtcgct gccgtaacgc agaccgataa aaccaacaat
     3721 cagcgcgata atcgacggga aaataaacat gccgatgaca tgaccatcga acaggtaatt
     3781 tgcgccgaac agcgccacac ctgctgcgcc tgcaccacca aggttgtgag aaatgttcca
     3841 gaaaccgagg aatgtcccgc gtttacgacg cggcgtccat ttggtgatgg tggagtaact
     3901 gcacgaaccg ccggtactct ggaaaaagcc gcttaaggcg tagaaggcaa tcatcaggaa
     3961 caggctaacc gagccgctgc ccatactggc gctgaagccc agcatacaaa tggcagacag
     4021 gatcagcatg aacggcagga attgtttggt gtttttgccg tcggcgtagt aagaaaccag
     4081 cgttttaccc acgccataag tgatggagaa gcccaggccg atcatcccca gctgcgtcat
     4141 gctcaacccg taggtcgaga tcatgtcgtt ctgcgcgatg ttaaagttct tgcgaatcag
     4201 gtacatcgta aggtagccga taaagaccac caggtaggat tgcatgaacg gtttgaacca
     4261 cattttgcgc cgcacttcga gcggaaggtc cagggtcggc ttgcgaacct ggtttaagaa
     4321 agccagcatg ggttactcct gaaatgaata cctgcgtgag gcatgcattg taaaaatcag
     4381 cagcaaatca ggcctgagat agcgtccagg caaaacctgg aaaatttctt agttttgccg
     4441 gatatgaagt gaaaaggtga gatgcatcac gcttctcgcg gtgtctgggc gttcaaaaag
     4501 ggcagtaata gcagtgcgga aatcccggcg gcgatggcga taaccacaaa aaatccgctc
     4561 cagtgccagg tatcgagtac tttcgccagc ggccaaccag caagcgacgc accaagataa
     4621 gcaaacaagc cgacaaatcc cgtcgccgcc cctgctgcct ctttgtggga acactctgcc
     4681 gccgccatgc cgattaacat ctgcgggcca aagacaaaaa aaccaatggt gaagaagcag
     4741 gttgcctgca tcacgtagct ggcaaatggc atcagccaca gcgagccgac tgaaagcaaa
     4801 attccggcag cgaaaatcaa attcatcggc ccgcggttgc cgttaaagag tttgtccgag
     4861 ccccaacccg ctaccagcgc accgataaat ccgcccagtt caaacatcgt cacagccgta
     4921 ttcgccgtga ccagatcgac gcccagcgtc tcggacatat acaaattgcc ccagtcgttg
     4981 atcgccgccc gaaccacata gaccagcaca tagcaaaacg aaagtagcca gatatacgga
     5041 ttcagcaaca catacttggt gaggatctct ttacgcgtca gccctgcccc ttcttgttgt
     5101 tgagcaatct ccagcgcgtc gtgccgccat tcaccaaccg ctggtaaacc taacgcctgc
     5161 gggcgatcgc gcagccgcca gcagagaaaa atccccacga cgatcgccat acaaccagca
     5221 atcatcatcc cggcacgcca gccgtaatgc agcgcagctg ctgccatcac aatgggaatg
     5281 agcgcaccgc caacgttatg cgccgtgttc cataatgccc accaaccgcc gcgctcggta
     5341 cgagaatacc aggcggttaa cagacgcgca cacaccggtg aaccccagcc ctggaaaaag
     5401 gcgttcaaca cccagagcac ggcaaacgcc catagcgacg tcgagaagcc aaacagaatg
     5461 ttgataatgc ccgtggcgat aagccctatc cccataaaat aacgggcatt tgagcggtcg
     5521 ctgacaatgc cggagacaaa cttcgacacg ccgtaagtaa tgtaaaacag ggtcgctaac
     5581 aggccgatat cgctacggct gagcacgccg ttagcaagga tttctggtac ggcggcgtta
     5641 aaacttttac gcgtgaagta aaacagcgcg taacccagcc agatggtcag cagaatatgc
     5701 cgacgccagt agcgatagcg ggcatcaatt tcatgtttat cagtcattaa tggcgcatcg
     5761 gcaggcgctt tcagaaacgg caacatcatc gaaccttaga catagcgttg aggtagagaa
     5821 acgctgacac gcgtgccgtg caaacaggag atggtcaagg tgccgcccag cgccgttacg
     5881 cgctcgcgca ttccggtgag gccaaaacct tgttgcccgg aacccggcgg caaaccgctg
     5941 ccatcgtctt caattaccag catcaaccgt tcatcctgct gccagccttg cagggtgacc
     6001 gcgctggcat cggcatgttt cacaatgttg ttcaaccctt cctggcagac gcgaaacagc
     6061 gtcacgcgct ggttttcgct taacgctgat tcatcgattc gccattcgag atgactgaca
     6121 atgccgcgcc cttccagctc catttcccgc atcagtgagc ggatggcctg ctccagggtg
     6181 agatcatcca gctggcgcgg acgtaaccgc cctaacaaac ggcgcaccgc atcgtaaaca
     6241 cccagcgaca gttgttcgat gagctgcccg ctctgcttca cgctggcgtt atctgccgcc
     6301 agccgctgaa caatacctgc ttgagtacga atagcagtga tggtctgacc gatatcgtcg
     6361 tgcagctcac gcgccacatc acggcgcacg ctctcttcag tttctaacaa acgttcagcc
     6421 agatgctgat tgcgcgctag ttccttttgc agcgactggt taagttcacg caaccgctgg
     6481 atgcctgcgc ccagtaacaa ccctgtcaga ctttgcacca gcagcgagag caataaatcc
     6541 accgaatgat cgcgccaggt ttgactggcg atcagcgcga tggcgttcat caacgtcgca
     6601 atcagcgccc cttgccagcc gtagtgccag gccagcgcga taatcggcag cgccaggcag
     6661 aatggcgtaa agcgcgacag ttcgtccggc aatcccaact ggagccagag actgataaca
     6721 aacagcagca agtaccagac cagatgccgc ccgcgccagt tgatcggttg agaaactaac
     6781 gacggcccga gcggcagcca gatgttattg gcgagatagt gccagaacac cagacatatc
     6841 ggggccagcg tcaggccgcc agttaaagtc agcaacagcg cattccacga ctctttcccg
     6901 tgccaaagcc agggcagcga ctgcaacaac gccgccgccg tcagcgccgc accctgtaac
     6961 agcaaggtgc gccagtcacg ttgatggcga tagcgcgaga tcagcgccac gggcaataac
     7021 gtcagtaaac taccgatcat caataaggag aaatgggtta aaccgaccgc ctgcattagc
     7081 cagtaaatca gcagccactc cgcacccagt agcaccggcc agtatccgcg cgggcattgc
     7141 agcattagcc ctagccgcag gccaaacgga aataacagca ccgccatatc agggcgctca
     7201 acaaggtgca ggctgatact ccacaggcaa aaccatgcgg cagagaagat aaaaaagcag
     7261 gcaataacgg taattaagcg agagaaaaac gtcttcatca ccagccatca aacatgcggc
     7321 gcgccagttc aacgtcgtta ctgacgccca gtttttccat caggttagcg cgatggacgt
     7381 gtaccgtttt cggtgacaag cccagttcgg cggcaatctc tttcaccgcc attccttgcg
     7441 ccagtttttc cgccacctgg cgttcgcgtt tggtcagcgg gtcctggcga ccggatgcca
     7501 gtttaatggc aatatccggc gtcagataac agccgcccgt ggcaaccgta tgcaccgcag
     7561 caatcagttc gtcagggcta caacgcttgg agagaaagcc gcgcgccccc gcgttaagcg
     7621 cctgctcaac cagcgccgga ctgtcatgaa cagagagcat aatcgtcgcc atacctttcg
     7681 gcagctggct tagcagctcc agaccggaga tatcgggcat ggagatatcg caaatacaca
     7741 cctgcacacc gcgccccggc agccccgcca acgcctcgcg ccccgaacca aactcggcaa
     7801 ctacctgcaa atcaggttcc agccccagca gctgcgcaaa gccggagcgg acgatgaggt
     7861 gatcgtctat aagtgcaacg gtgatcatga ttgggtcctg gcggataaaa aacgcgcata
     7921 ccttaacgat aagcgcgatg ttgttcaagt tggatatggg gtatgtattg gcttaatgat
     7981 gttggtctta tcgtcaaaac gcttacctga aaggtaagcg tttggtacgt gttattgcga
     8041 aaaagcgaat tatttgtagg ttgcgattgc aatattgcct gaaaaatttc tcctcctgtt
     8101 gcggaaatcg ttttcaggta acaaagagtc atccagaaac ctataatctt cagcggaacg
     8161 ctcattaaga gagtcatcca ctgagtcgtt atgaatataa tcctcaccgt atgttcgata
     8221 aatgaaatta gcaatattaa aatcgttacc agcttcattt atttcggctt ttacaatata
     8281 atgggtttgt gtgaatgtat gctgtgaaaa gtcagcaaca agcaaatttg tttttcccag
     8341 caaagcacaa aaccctgggt tatcatcaag cccggcagaa acagaatcgt ttgcctgtat
     8401 tacattaata tcccccctat caagcgcgac aggaaatgcc tgtgaacaag cataatacag
     8461 gttacctatt cctgaaatac tggagaggca agaaataata ttttctctga tttttttctc
     8521 aacaccatct ttctgtagag agtttctcac aatattacat tcatctggcg taaatacaat
     8581 ttcactaaaa agcttttcga aagctttata ttttctaaca cctccatggc cagacaaagc
     8641 catggtttta ttcctcagaa attcatggat tgtgctattt attttaactc cacaacatga
     8701 aataattgag ctaccctctc caacgtgtct tgctgcatca gcaagaagtg aactaaactc
     8761 tccctccaga acatctagtt ttttatgtct gatttataac tacaatcatc tggaattaat
     8821 ttatctggag ttaattgagt ttgttcattt aacgcttttt ttaattggcg ctcagcatca
     8881 gtaactccaa aactgcgttt attttcagaa ttattattaa caacttctag cttaagagca
     8941 tttgcagcaa ctgttacttt tgagagttga tacttttcca atacatcgtg ctctgataat
     9001 aaccctataa actctttcac attacgacca ctaaaatccc tgtctctact ctgttttttc
     9061 aaactgttgc cttttaactc acgatacaca tcagtgactt taaacttatc actgccggtc
     9121 tgctcaattt ttatatagct atccatccct gtggtagcga tccatgtttt ataattcgca
     9181 ttcgctgatt caggcgtaac atgaaaataa gaaaccaatt taccactgat atcatgccga
     9241 tagatatgta aagaatctaa aatgtataat aataaacttc ggaaaacctc acgaaaagtg
     9301 gcatttttag ataatgttct acaattatcg agcaggccac tttgttccat cgcatcaaat
     9361 gcttcaatat taccctcgat actatctctt agactctggc tcaggccctg gctctgagtt
     9421 tgactctgaa aatgactatt atcattctct gtttccgttg gatatgtata actcgtcaca
     9481 ctaaccatag taacctcgca atatgacact ttgcatattt tgacattgtt agaagtatca
     9541 atggctagca tgataaatat ttcattgcta accgctattt ttcatttatt tcaataataa
     9601 gactatagtg ccgttaattt ttatcgattt ccccaatgca attgcatcac taattctact
     9661 tattcactat caaaaatcgc tcattttttt caaaaagact gtttacacac agacggttaa
     9721 gaataagcgt tcaccttaat gataaacgcg atttatcagg caaaaatcat aaatcagcag
     9781 ttgttgcggc accgaagaat gtaaaagcga ctttatctat tttggagttt tctttgtcga
     9841 ccctaccggt agtaaaataa cgagaacact gaagcttaac ttcatttcca acattattaa
     9901 ccgccatcaa atacatcttc tgactaaacc catttatagt aaaatccatt tctttaagat
     9961 atttcccagt cccaaaaaag gtatttcctg agttttttaa acccgatgtt gatgaaatgg
    10021 catcatccaa actctttgag agtaactcgc taacatcttg agatgtattt tttaaatagc
    10081 tctgatagcc ttgtacggaa gaataataaa aacatgtaat cccctgatga ctggataagc
    10141 aagcgattat ttcatcaatc ttatcatccg caatgttacc atttgatttc tttaataatt
    10201 cccttacccg agcacagtca ttatcattaa agtaaaccag ttcaaccatt tgttcaaatg
    10261 tgttttgact attctttgta tcttgttcaa ttatttcaat tttctctgca aatattttaa
    10321 gaatatcttt acttaactca acaccgcagc aagttatttt agtagcacca ttttgttgat
    10381 tttgttcttt tatagttcta tgagcatcca taattatgga atcaaaaaaa acatctgttc
    10441 ttttaaaact ttcctgaa
//
LOCUS       DADXDL010000128        10300 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.128, whole genome shotgun sequence.
ACCESSION   DADXDL010000128 DADXDL010000000
VERSION     DADXDL010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 10300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10300
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.128"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(260..1660)
                     /gene="asnS"
                     /locus_tag="IRB70_004343"
     CDS             complement(260..1660)
                     /gene="asnS"
                     /locus_tag="IRB70_004343"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005123540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBC0634183.1"
                     /translation="MSVVPVADVLQGRVAVDSEVTVRGWVRTRRDSKAGISFLAVYDG
                     SCFDPVQAVINNSLPNYNEDVLRLTTGCSVIVTGKVVASPGQGQQFEIQASKVEVAGW
                     VEDPDTYPMAAKRHSIEYLREVAHLRPRTNLIGAVARVRHTLAQALHRFFNEQGFFWV
                     STPLITASDTEGAGEMFRVSTLDLENLPRNDQGKVDFDKDFFGKESFLTVSGQLNGET
                     YACALSKIYTFGPTFRAENSNTSRHLAEFWMLEPEVAFANLNDIAGLAEAMLKYVFKA
                     VLEERADDMKFFAERVDKDAVSRLERFIEADFAQVDYTDAVTILENCGRKFENPVYWG
                     VDLSSEHERYLAEEHFKAPVVVKNYPKDIKAFYMRLNEDGKTVAAMDVLAPGIGEIIG
                     GSQREERLDVLDERMLEMGLNKEDYWWYRDLRRYGTVPHSGFGLGFERLIAYVTGVQN
                     VRDVIPFPRTPRNASF"
     gene            complement(1828..3030)
                     /gene="pncB"
                     /locus_tag="IRB70_004344"
     CDS             complement(1828..3030)
                     /gene="pncB"
                     /locus_tag="IRB70_004344"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBC0634184.1"
                     /translation="MTQFASPVLHSLLDTDAYKLHMQQAVFHHYYDVHVAAEFRCRGD
                     DLLGIYADAIREQVQAMQHLRLQDDEYQWLSALPFFQADYLNWLREFRFNPEQVTVSN
                     DNGKLDIRLSGPWREVILWEVPLLAVISEMVHRYRSPQTDVAQALDTLESKLVDFSAL
                     TAGLDMSRFHLMDFGTRRRFSREVQETIVKRLQQEPWFVGTSNYDLARRLSLTPMGTQ
                     AHEWFQAHQQISPDLANSQRAALAAWLEEYPDQLGIALTDCITMDAFLRDFGVEFASR
                     YQGLRHDSGDPVEWGEKAIAHYEKLGIDPQSKTLVFSDNLDLRKAVELYRHFSSRVQL
                     SFGIGTRLTCDIPQVKPLNIVIKLVECNGKPVAKLSDSPGKTICHDKAFVRALRKAFD
                     LPHIKKAS"
     gene            3296..5908
                     /gene="pepN"
                     /locus_tag="IRB70_004345"
     CDS             3296..5908
                     /gene="pepN"
                     /locus_tag="IRB70_004345"
                     /EC_number="3.4.11.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000193787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase N"
                     /protein_id="HBC0634185.1"
                     /translation="MTQQPQAKYRHDYRAPDYQITDIDLTFDLDAQKTVVTAVSQAVR
                     HGASDAPLRLDGEDLKLVSVHINDEPWTAWKEEEGALVISNLPERFTLKIVNEISPAT
                     NTALEGLYQSGDALCTQCEAEGFRHITYYLDRPDVLARFTTKIIADKTQYPFLLSNGN
                     RVAQGELENGRHWVQWQDPFPKPCYLFALVAGDFDVLRDTFTTRSGREVALELYVDRG
                     NLDRAPWAMTSLKNSMKWDEERFGLEYDLDIYMIVAVDFFNMGAMENKGLNIFNSKYV
                     LARTDTATDKDYLDIERVIGHEYFHNWTGNRVTCRDWFQLSLKEGLTVFRDQEFSSDL
                     GSRAVNRINNVRTMRGLQFAEDASPMAHPIRPDMVIEMNNFYTLTVYEKGAEVIRMIH
                     TLLGEENFQKGMQLYFERHDGSAATCDDFVQAMEDASNVDLSHFRRWYSQSGTPVVTV
                     KDDYNPETEQYTLTISQRTPATPDQAEKQPLHIPFAIELYDNEGKVIPLQKGGHPVNS
                     VLNVTQAEQTFVFDNVYFQPVPALLCEFSAPVKLEYKWSDQQLTFLMRHARNDFSRWD
                     AAQSLLATYIKLNVARHQQGQPLSLPVHVADAFRAVLLDEKIDPALAAEILTLPSVNE
                     MAELFDIIDPIAIAEVREALTRTLATELADELLAIYNANYQSEYRVEHEDIAKRTLRN
                     ACLRFLAFGETHLADVLVSKQFHEANNMTDALAALSAAVAAQLPCRDALMQEYDDKWH
                     LDGLVMDKWFILQATSPAANVLETVRGLLQHRSFTMSNPNRIRSLIGAFAGSNPAAFH
                     AEDGSGYQFLVEMLTDLNSRNPQVASRLIEPLIRLKRYDAKRQEKMRAALEQLKGLEN
                     LSGDLYEKITKALA"
     gene            complement(5951..6718)
                     /gene="ssuB"
                     /locus_tag="IRB70_004346"
     CDS             complement(5951..6718)
                     /gene="ssuB"
                     /locus_tag="IRB70_004346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonates ABC transporter ATP-binding
                     protein"
                     /protein_id="HBC0634186.1"
                     /translation="MNTARLNQGTPLLLNAVSKHYAENIVLNQLDLHIPAGQFVAVVG
                     RSGGGKSTLLRLLAGLETPTAGDVLAGTTPLAEIQEDTRMMFQDARLLPWKSVIDNVG
                     LGLKGQWRDAARRALAAVGLENRAGEWPAALSGGQKQRVALARALIHRPGLLLLDEPL
                     GALDALTRLEMQDLIVSLWQEHGFTVLLVTHDVSEAVAMADRVLLIEEGKIGLDLTVD
                     IPRPRRLGSVRLAELEAEVLQRVMQRGESETRLRKQG"
     gene            complement(6715..7506)
                     /gene="ssuC"
                     /locus_tag="IRB70_004347"
     CDS             complement(6715..7506)
                     /gene="ssuC"
                     /locus_tag="IRB70_004347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415454.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter permease
                     SsuC"
                     /protein_id="HBC0634187.1"
                     /translation="MATPVKKWLLRVAPWFLPVGIVAVWQLASSVGWLSTRILPSPEG
                     VVMAFWTLSASGELWQHLAISSWRALIGFSIGGSLGLILGLISGLSHWGERLLDTSIQ
                     MLRNVPHLALIPLVILWFGIDESAKIFLVALGTLFPIYINTWHGIRNIDRGLVEMARS
                     YGLSGIPLFIHVILPGALPSIMVGVRFALGLMWLTLIVAETISANSGIGYLAMNAREF
                     LQTDVVVVAIILYALLGKLADVSAQLLERLWLRWNPAYHLKEATV"
     gene            complement(7517..8662)
                     /gene="ssuD"
                     /locus_tag="IRB70_004348"
     CDS             complement(7517..8662)
                     /gene="ssuD"
                     /locus_tag="IRB70_004348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMNH2-dependent alkanesulfonate monooxygenase"
                     /protein_id="HBC0634188.1"
                     /translation="MSLNMFWFLPTHGDGHYLGTEEGSRPVDHGYLQQIAQAADRLGY
                     TGVLIPTGRSCEDAWLVAASMIPVTQRLKFLVALRPSVTSPTVAARQAATLDRLSNGR
                     ALFNLVTGSDPQELAGDGVFLDHSERYEASAEFTQVWRRLLLGETVDFNGKHIHVRGA
                     KLLFPPIQQPYPPLYFGGSSDVAQELAAEQVDLYLTWGEPPELVKEKIEQVRAKAAAH
                     GRKIRFGIRLHVIVRETNDEAWQAAERLISHLDDETIAKAQAAFARTDSVGQQRMAAL
                     HNGKRDNLEISPNLWAGVGLVRGGAGTALVGDGPTVAARINEYAALGIDSFVLSGYPH
                     LEEAYRVGELLFPHLDVAIPEIPQPQPLNPQGEAVANDFIPRKVAQS"
     gene            complement(8659..9618)
                     /gene="ssuA"
                     /locus_tag="IRB70_004349"
     CDS             complement(8659..9618)
                     /gene="ssuA"
                     /locus_tag="IRB70_004349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415456.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aliphatic sulfonate ABC transporter
                     substrate-binding protein SsuA"
                     /protein_id="HBC0634189.1"
                     /translation="MRKLIKLALAGLLSVSTLAVAAESSPEALRIGYQKSNISSVLAK
                     NHLLLEKRYPQTKISWVEFPAGPQMLEALNVGSIDLGSTGDIPPIFAQAAGADLLYVG
                     VEPPKPKAEVILVAENSPIKTVADLKGHKVAFQKGSSSHNLLLRALRQAGLKFTDIQP
                     TYLTPADARAAFQQGNVDAWAIWDPYYSAALLQGGVRVLKDGTDLNQTGSFYLAARPY
                     AEKNGAFIQGVLTTFSEADALTRSQREQSIALLAKTMGLPAPVIASYLDHRPPTTIKP
                     LSAEVAALQQQTADLFYENRLVPKKVDIRQRIWQPTQLEGKQL"
     gene            complement(9611..10186)
                     /gene="ssuE"
                     /locus_tag="IRB70_004350"
     CDS             complement(9611..10186)
                     /gene="ssuE"
                     /locus_tag="IRB70_004350"
                     /EC_number="1.5.1.38"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent FMN reductase"
                     /protein_id="HBC0634190.1"
                     /translation="MRVITLAGSPRFPSRSSSLLEYAREKLNGLDVEVYHWNLQNFAP
                     EDLLYARFDGPALKTFTEQLQQADGLIVATPVYKAAYSGALKTLLDLLPERALQGKVV
                     LPLATGGTVAHLLAVDYALKPVLSALKAQEILHGVFADDSQVIDYQHKPLFTPNLQTR
                     LDTALETFWQALHRRDVQVPDLLSLRGNAHA"
BASE COUNT         2530 a         2785 c         2669 g         2316 t
ORIGIN      
        1 atcgacctgg cactaaatcc tcgttcagac atccagaacg ccaaaaaata gtatgaaaat
       61 tgtgctatca gctaaaaaaa aactaatccg caataagaat gcggattatt ttttgtgcgc
      121 aaatgttgca gtgtaatatt ccgtaacaga atgatcgtta tggcggggtt gcaaatagat
      181 tgcttgactt aacaaacaga taacttgaca gaaaggataa aaaaagagcc agcgggcgct
      241 ggctcttgaa gacgctaaat tagaagctgg cgttacgcgg agtacgtggg aacggaatca
      301 catcacgcac gttttgcaca ccagttacgt aagcaatcag gcgttcaaaa ccaagaccga
      361 aacctgaatg cggaacagta ccgtagcgac gcagatcgcg ataccaccag taatcttctt
      421 tattcaggcc catttccagc atacgctcgt ccagcacgtc cagacgttct tcacgctggg
      481 agccaccaat gatctcaccg atgcccggag ccagaacgtc catagccgca acggttttac
      541 cgtcttcgtt aaggcgcata tagaacgctt taatatcttt cggatagttt ttaaccacta
      601 ccggtgcttt aaagtgttct tccgccagat aacgctcatg ctcagaagag agatcaacgc
      661 cccagtaaac cgggttttca aacttcctgc cgcagttttc gagaatggtc actgcgtcgg
      721 tgtaatccac ctgcgcaaaa tcggcttcaa tgaagcgttc cagacgtgaa acggcatctt
      781 tatctacgcg ttcagcgaag aatttcatgt cgtcagcgcg ttcttcgaga accgctttga
      841 agacatattt cagcatggct tcagccagac ccgcgatatc gttcaggtta gcaaacgcca
      901 cttccggctc cagcatccag aattccgcca ggtgacggct ggtgttggag ttttcagcac
      961 ggaaagtcgg gccgaaggta taaattttgg ataatgcgca agcgtaggtt tcgccgttca
     1021 actggccaga tacggtcagg aaagactctt taccaaagaa gtctttgtcg aaatccactt
     1081 tgccctgatc gttacgcggc aggttttcca gatccagcgt agaaacgcgg aacatttcgc
     1141 cagcaccttc ggtatcagac gcagtaatca gtggcgttga aacccagaag aatccctgct
     1201 cgttaaagaa gcgatgcagc gcctgcgcca acgtatggcg aacgcgcgcg acggcaccaa
     1261 tcaggtttgt gcgcggacgc aggtgagcga cttcacgcag atactcaatg ctgtggcgtt
     1321 ttgccgccat cgggtaagtg tctggatctt caacccaacc agcaacttca accttgctgg
     1381 cctgaatttc aaattgttgc ccctggcccg gcgacgccac gactttaccc gtcacaatga
     1441 ccgagcagcc ggtggtcaga cgcaggacgt cttcattgta attgggcaga gaattattga
     1501 tgacagcctg tacaggatca aagcaggaac cgtcataaac ggcgaggaag gagatgccag
     1561 cttttgaatc tcggcgggta cgtacccatc cgcgcacggt gacttcgctg tcaacggcta
     1621 cgcggccctg gagtacgtcg gctacaggca caacgctcat aatattctct ctgttaatag
     1681 tcggaaaaaa taaacacttg tccacccgta aatgggggga tacctatgtt acctggcatc
     1741 tgcaatcaga caagcagaat tcgcaaatgc agcgaaagat ttcggaatta aaggtaaaaa
     1801 agggagccga ttagctccct gatgatatta actggctttt ttaatatgcg gaaggtcgaa
     1861 tgctttgcgc agtgcccgaa caaacgcttt atcgtggcag atagttttgc cagggctgtc
     1921 agaaagtttc gccaccggtt taccgttaca ctcaaccaac ttaatgacaa tattcagggg
     1981 ttttacctgg gggatatcgc aggtcaggcg agtcccaata ccaaaactta attgcacgcg
     2041 ggaagagaaa tggcggtata gctcaaccgc tttgcgtaaa tccagattgt cagagaaaac
     2101 cagcgtttta ctctgtggat caattcccag cttctcataa tgtgcaatgg ctttttcacc
     2161 ccattcaacc gggtcgccag agtcatgacg caggccctga tagcgactgg cgaactcgac
     2221 accgaaatca cgcaggaaag catccatagt gatgcagtcg gttaatgcaa tgccaagttg
     2281 gtcgggatat tcttccagcc aggcagcaag tgcagctcgc tggctgttgg ctagatccgg
     2341 gctgatttgc tgatgcgcct ggaaccattc gtgtgcctgt gttcccatcg gcgtgaggga
     2401 aagccggcgc gccagatcat agttgctggt gcccacgaac cagggttcct gttgcagacg
     2461 cttaacgatg gtttcttgta cttcgcgaga aaaacggcgg cgggtgccaa aatccatcag
     2521 atggaagcgc gacatatcaa gaccggcggt taatgccgag aagtcgacta atttgctttc
     2581 cagcgtgtcg agggcttgcg caacgtcggt ctgcggtgag cgatagcgat gtaccatttc
     2641 actgataacc gccagcaaag gaacttccca gaggatgact tcacgccacg ggccgcttaa
     2701 acgaatatcc agcttgccat tatcgttgga tacggtgact tgttccgggt taaagcggaa
     2761 ctcgcgtaac cagttaagat agtcggcctg aaagaaaggc agggcagaga gccactgata
     2821 ttcatcatcc tgcaggcgca ggtgctgcat cgcctgaacc tgttcacgaa tagcatcggc
     2881 ataaataccc agcagatcgt cacctcggca acgaaactcc gccgcgacat gcacatcgta
     2941 atagtgatga aacacggctt gctgcatatg caacttataa gcatctgtat ccagcaacga
     3001 gtgcagaaca ggagaagcga attgtgtcat aggtgcgcag tagcgtcctc gtacaggagc
     3061 gtttagtaca ataaacatct tcaggaactg ctggagtata ccttgtttcg caatttattg
     3121 aaccccgatc acaccatatg ccacctttct ggtcgatggc attacgcggt gtatgttata
     3181 aaaatgtagc aataaaggcg tttgtacctg aaaagatgaa gattctgcat agcgcgattt
     3241 acgcaacagg aatagactga acaccagact ctataaaaga tgctaaaggt tatttatgac
     3301 tcaacagcca caagccaaat accgtcacga ttatcgtgcg ccggattacc agattactga
     3361 tattgacttg acctttgacc tggacgcgca aaagacggtc gttaccgcgg tcagccaggc
     3421 tgtccgtcat ggtgcatcag atgctccgct tcgtcttgat ggtgaagatc ttaaactggt
     3481 ttctgttcat attaatgatg agccgtggac cgcctggaaa gaagaagagg gcgcactggt
     3541 catcagtaat ttgccggagc gttttacgct taagatcgtt aatgaaatta gcccggcgac
     3601 gaataccgcg ctggaagggc tttatcagtc aggcgatgcg ctttgcaccc agtgtgaagc
     3661 cgaaggtttc cgccatatta cgtattatct cgaccgcccg gacgtgctgg cgcgttttac
     3721 caccaaaatt attgccgata aaacccaata tcccttcctg ctttccaacg gtaaccgcgt
     3781 tgcgcaaggc gaactggaaa acggacgtca ctgggtacag tggcaggacc cgttccctaa
     3841 accgtgctac ttgtttgcgc tggtggcagg cgacttcgac gtgctgcgcg acaccttcac
     3901 cacgcgttct ggtcgcgaag ttgcgctgga gctgtacgtc gatcgcggca accttgatcg
     3961 tgcgccgtgg gcgatgacct cgctgaaaaa ctccatgaaa tgggatgaag agcgcttcgg
     4021 cctggagtat gacctcgaca tctatatgat cgtcgcggtg gatttcttca atatgggcgc
     4081 aatggagaat aaggggctga atatctttaa ctccaaatat gtgctggccc gcaccgatac
     4141 cgccaccgac aaagattacc tcgatattga acgcgttatc ggccatgaat atttccataa
     4201 ctggaccggt aaccgagtga cctgccgcga ctggttccag ctcagcctga aagaaggttt
     4261 aaccgtcttc cgcgatcagg agttcagctc tgaccttggt tctcgcgcgg taaaccgtat
     4321 caacaacgtg cgcaccatgc gcggattgca gtttgcggaa gacgccagcc cgatggcgca
     4381 cccgatccgc ccggatatgg tcattgagat gaacaacttc tacaccctga ccgtttacga
     4441 gaagggcgcg gaagtgattc gcatgatcca caccctgctg ggcgaagaaa acttccagaa
     4501 agggatgcag ctctatttcg agcgccatga tggcagcgcg gcaacctgcg acgactttgt
     4561 tcaggcgatg gaagatgcgt cgaatgtcga tctctctcat ttccgccgtt ggtacagcca
     4621 gtccggtacg ccggttgtga ccgtcaaaga cgactataat ccggaaaccg agcagtacac
     4681 cctgaccatc agccagcgta cgcctgctac gccggatcag gcagaaaaac agccgctgca
     4741 tattccgttt gcaatcgaat tgtatgataa cgaaggcaaa gtgatcccgt tgcagaaagg
     4801 cggtcatccg gtgaattccg tgctaaacgt cactcaggcg gaacagacct ttgtctttga
     4861 taatgtctac ttccagccgg tgcctgcgct gctgtgcgaa ttctctgcgc cagttaaact
     4921 ggaatataag tggagcgatc agcaactgac cttcctgatg cgtcatgcgc gtaatgattt
     4981 ctcccgttgg gatgcggcgc aaagcctgct ggcaacctac atcaagctaa acgtcgcccg
     5041 tcatcagcaa gggcagccgc tgtctctgcc ggtgcatgtg gctgacgctt tccgcgcggt
     5101 gctgctcgat gagaagattg atccggcgct ggcggcagaa atcctgacgc tgccttctgt
     5161 caatgaaatg gctgaactgt tcgatatcat cgacccgatt gctattgccg aagtacgcga
     5221 agcactcact cgtactctgg cgactgaact ggcggatgag ctgctggcta tttacaacgc
     5281 gaattaccag agcgagtacc gtgttgagca tgaagatatt gcgaaacgca ctctgcgtaa
     5341 tgcctgcctg cgcttccttg cttttggtga aacgcatctg gctgacgtgc tggtgagcaa
     5401 gcagttccac gaagcgaaca atatgaccga tgcgctggcg gcgctttctg cggcggttgc
     5461 cgcacaactg ccatgccgtg atgcgctgat gcaggaatac gacgataagt ggcatctgga
     5521 cggtctggtg atggataaat ggtttatcct gcaagccacc agcccggcgg cgaatgtgct
     5581 ggagacggtg cgcggtctgt tgcagcatcg ctcatttacc atgagcaacc cgaaccgcat
     5641 tcgttcgttg attggcgcgt ttgctggcag caacccggca gcgttccatg ccgaagatgg
     5701 cagcggttat cagttccttg tggaaatgct taccgacctc aacagccgta acccgcaggt
     5761 ggcatcgcgc ctgattgagc cgttgattcg cctgaaacgt tacgatgcca aacgtcagga
     5821 gaaaatgcgc gcggcgctgg agcagttgaa agggctggaa aatctctctg gcgatctgta
     5881 cgagaagata actaaagcac tggcttgata aataaccgaa tggcggcaat agcgccgcca
     5941 ttcggagaac ttacccctgt tttctcaggc gagtttcaga ttcaccacgc tgcatcaccc
     6001 gttgcaacac ttccgcttcc agctccgcta atcgcaccga ccctaaccgg cgcggacggg
     6061 ggatatccac cgtcaaatcc agaccaattt ttccctcttc aattaacaac acccggtcag
     6121 ccattgctac cgcttcgctc acatcatgcg tcaccaacag tacggtaaag ccgtgctcct
     6181 gccaaagtga cacaatcaaa tcctgcatct cgagtcgcgt taaggcgtcc agtgccccga
     6241 gcggttcatc aagcaacaat aaacccggtc gatgaatcaa cgctcttgcc agcgccactc
     6301 gctgtttctg cccgcctgaa agtgcggcag gccattcccc ggcgcgattc tccagtccta
     6361 ccgcagccaa cgcccgacgc gcggcatcgc gccactggcc tttaaggcct aacccaacgt
     6421 tatcaatcac cgatttccac ggtagcagac gcgcatcctg aaacatcatt cgcgtgtctt
     6481 cctgaatctc agctagcggt gtggtacccg ctaacacatc gcctgcggtt ggcgtttcca
     6541 gacctgccag caggcgcagc agggtacttt tgccaccacc gctgcggccc accaccgcca
     6601 caaactgacc tgccggaata tgtaaatcca gttggttcag aacgatattt tctgcgtaat
     6661 gtttgcttac tgcattgagt aacaagggtg tgccctggtt cagacgagca gtattcatac
     6721 cgtggcctcc ttcaaatgat aagccggatt ccagcgcagc cagaggcgct ctaacagctg
     6781 cgcgctgacg tcagcaagtt tgccgagcag tgcgtagaga ataatggcga ctaccaccac
     6841 atccgtttgc aaaaactccc gcgcattcat cgccagataa ccaatgccgg aattggcaga
     6901 aatggtttcg gcaacaatca gcgtcagcca catcaggccc aacgcaaaac gtacgccgac
     6961 cataattgag ggcagggcac caggcaggat cacatggata aacagcggta tgccggataa
     7021 tccatagcta cgcgccattt ccaccagacc gcgatcgata ttacggatgc cgtgccaggt
     7081 gttgatataa atggggaata gagtgccgag cgccaccaga aagatttttg cggattcatc
     7141 aatgccaaac cacaaaatca ccagcgggat cagcgccaga tgcggcacgt tgcgcaacat
     7201 ctgaatggag gtatccagca gccgttctcc ccagtgcgac agcccgctaa tcagtcccag
     7261 aatcaagccc agcgatccgc caattgaaaa gccaatcaac gcccgccagg agctgatcgc
     7321 cagatgctgc cacaattcgc cgctggcaga gagcgtccag aacgccatca ccactccttc
     7381 cggtgagggc aaaatacgcg tcgatagcca gccaaccgag gaggccagtt gccacaccgc
     7441 cacgatgccc accggtaaaa accagggggc aacgcgcaat aaccacttct tcactggcgt
     7501 tgccattatt tcttccttag ctttgcgcga ccttacgggg gataaaatca ttcgccaccg
     7561 cttcgccttg cggattcagc ggttgtggct ggggtatttc cgggatggca acatccagat
     7621 gcgggaacag caactcgcca acccgatacg cttcttccag atgcgggtag cccgaaagca
     7681 caaagctgtc gatgccaagc gcggcgtatt cgttgattcg cgcagcgacc gtcggaccat
     7741 cgcccaccag tgccgtcccg gcaccgccgc gcactaagcc aacacccgcc cataaattgg
     7801 ggctgatctc cagattgtcg cgcttgccgt tatgtagcgc cgccattcgc tgttgtccta
     7861 cggaatccgt tcgggcgaat gcggcctgtg ctttggcgat agtttcatca tcaagatgcg
     7921 agattaaccg ctcggcggcc tgccacgctt cgtcgttggt ttcacgaaca atcacatgca
     7981 gacgaatacc gaaacgaatt ttgcgtccat gcgcggcagc tttcgcccgc acttgttcga
     8041 ttttctcttt taccagttcc ggtggttcgc cccaggtgag gtagagatca acttgttctg
     8101 ccgccagctc ctgggcgaca tctgacgatc cgccaaagta aagcggagga taaggctgtt
     8161 gaatcggcgg gaagagcagt ttggctccgc gtacatgaat atgtttgccg ttgaaatcca
     8221 ctgtctcgcc aagcaacaac cgccgccaga cttgggtaaa ttctgccgag gcttcgtaac
     8281 gctcgctatg atcaaggaac acgccgtcgc ctgccagttc ttggggatcg ctgcctgtga
     8341 ccaggttaaa caacgcacgt ccgttagaga gacggtcaag cgtggcggcc tggcgggcgg
     8401 caacggtagg cgatgtcaca ctggggcgca gggcgacaag aaacttcagc cgttgtgtca
     8461 ccgggatcat cgacgccgcc accagccacg catcttcaca cgatcgcccc gtcgggatca
     8521 gcacaccggt atagcccaga cgatccgccg cttgcgcaat ttgttgcaga taaccgtgat
     8581 caaccggacg tgaaccttct tccgttccca gataatgccc gtcaccgtgg gtcggtaaaa
     8641 accagaacat attcagactc ataattgttt tccttccagt tgagtgggtt gccagatgcg
     8701 ctggcgaata tcgacttttt tcggcaccag acggttttca taaaacagat ctgccgtttg
     8761 ctgctgtaag gcggcaactt cagcgctcaa cggtttgatg gtggtgggag gacgatgatc
     8821 cagatacgag gcaataaccg gtgccggtaa gcccatcgtt tttgccagta aagcgatgct
     8881 ttgttcgcgc tggctgcggg ttaacgcatc ggcctcacta aaggttgtca gcacaccctg
     8941 aataaaagcg ccgttttttt ctgcatacgg acgagctgcc agataaaacg atccagtttg
     9001 attgagatcg gtgccgtctt tcagcacccg cacgccgccc tgtaataacg cagcggagta
     9061 gtagggatcc cagatcgccc aggcgtcaac gttaccttgc tggaacgcgg cgcgggcatc
     9121 ggcaggcgtc aggtaagtgg gctgaatatc cgtgaattta agcccggcct ggcgaagggc
     9181 tcgcagtaaa agattgtgcg aactggaacc tttctgaaag gcaactttgt gacctttaag
     9241 atcggctacg gttttgatcg ggctgttttc tgccaccaga atcacctcgg cttttggctt
     9301 cggcggctcg acgcccacat acagcaaatc agccccggca gcctgggcga agattggcgg
     9361 aatatccccg gtactgccga gatcaatact gccaacgttt aacgcctcca acatttgcgg
     9421 tcccgcggga aactccaccc acgagatttt tgtttgcgga tagcgttttt ccagcaacag
     9481 gtggttttta gccagtaccg aactgatgtt gcttttctga tagccaatcc gtaacgcctc
     9541 gggcgaagac tctgcagcaa ccgcaagtgt agagacgcta agtaagcccg ccagcgccag
     9601 tttaatgagc ttacgcatgg gcattacctc gcagagacag aaggtcagga acctgaacat
     9661 cccgacggtg caatgcctgc cagaaagttt ctagcgcggt atcaagacgg gtttgcagat
     9721 ttggcgtgaa tagcggcttg tgctggtaat caatcacctg cgagtcatcg gcaaacacgc
     9781 cgtgcaggat ctcctgggct ttcagggcgc ttaaaactgg tttaagggcg taatcgaccg
     9841 ccagcagatg agccaccgtg ccgcccgtcg ccagtggcag taccactttg ccttgcaaag
     9901 cgcgttctgg cagcaggtcg agcagggttt tcagcgcgcc ggaataggcg gctttataca
     9961 caggtgtagc gacaatcagc ccatcggcct gttgcagctg ttcagtgaag gtcttgagtg
    10021 ccggaccatc gaaacgggca tagagcaaat cttccggggc gaagttttgc agattccagt
    10081 gataaacttc cacatccagg ccattcagtt tttcccgcgc atattccagc aaggagctgg
    10141 agcgagaagg aaagcgagga cttcctgcca gggtgatgac acgcatactc tctccttata
    10201 accaattgtt cttgttttgt taatattgat aacaattcgg tcagtctgtc ggagagacaa
    10261 gagaatgcca aatattaatt ttgtgtatct ttttctgaaa
//
LOCUS       DADXDL010000129         9949 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.129, whole genome shotgun sequence.
ACCESSION   DADXDL010000129 DADXDL010000000
VERSION     DADXDL010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9949
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.129"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(367..1503)
                     /locus_tag="IRB70_004351"
     CDS             complement(367..1503)
                     /locus_tag="IRB70_004351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyD family secretion protein"
                     /protein_id="HBC0634191.1"
                     /translation="MDLLIVLTYVALAWAVFKIFRIPVNQWTLATAALGGVFLVSGLI
                     LLMNYNHPYTFTAQKAVIAIPITPQVTGIVTEVTDKNNQLIQKGEVLFKLDPVRYQAR
                     VDRLQADLMTATHNIKTLRAQLTEAQANTTQVSAERDRLFKNYQRYLKGSQAAVNPFS
                     ERDIDDARQNFLAQDALVKGSVAEQAQIQSQLDSMVNGEQSQIVSLRAQLTEAKYNLE
                     QTVIRAPSNGYVTQVLIRPGTYAAALPLRPVMVFIPEQKRQIVAQFRQNSLLRLKPGD
                     DAEVVFNALPGQVFHGKLTSILPVVPGGSYQAQGVLQSLTVVPGTDGVLGTIELDPND
                     DIDALPDGIYAQVAVYSDHFSHVSVMRKVLLRMTSWMHYLYLDH"
     gene            complement(1506..1868)
                     /locus_tag="IRB70_004352"
     CDS             complement(1506..1868)
                     /locus_tag="IRB70_004352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3302 domain-containing protein"
                     /protein_id="HBC0634192.1"
                     /translation="MFLNYFALGVLIFVFLVIFYGIIAIHDIPYLIAKKRNHPHADAI
                     HTAGWVSLFTLHVIWPFLWIWATLYQPERGWGMQSHVASQEKATDPEIAALSDRISRL
                     EHQLAAEKKTDYSTFPEI"
     gene            2404..4317
                     /gene="mtlA"
                     /locus_tag="IRB70_004353"
     CDS             2404..4317
                     /gene="mtlA"
                     /locus_tag="IRB70_004353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBC0634193.1"
                     /translation="MSSDIKIKVQSFGRFLSNMVMPNIGAFIAWGIITALFIPTGWLP
                     NETLAKLVGPMITYLLPLLIGYTGGKLVGGERGGVVGAITTMGVIVGADMPMFLGSMI
                     AGPLGGWCIKHFDRWVDGKIKSGFEMLVNNFSAGIIGMILAILAFLGIGPVVEALSKM
                     LAAGVNFMVVHDMLPLASIFVEPAKILFLNNAINHGIFSPLGIQQSHELGKSIFFLIE
                     ANPGPGMGVLLAYMFFGRGSAKQSAGGAAIIHFLGGIHEIYFPYVLMNPRLILAVILG
                     GMTGVFTLTILGGGLVSPASPGSILAVLAMTPKGAYFANIAGVCAAMAVSFVVSAILL
                     KTSKVKEEDDIEAAARRVQEMKAESKGASPLSAGDVTNDLSHVRKIIVACDAGMGSSA
                     MGAGVLRKKIQDAGLSQISVTNSAINNLPPDVDLVITHRDLTERAMRQVPQAQHISLT
                     NFLDSGLYTSLTERLVAAQRHTENEVKVKDSLKDSFDDSSANLFKLGAENIFLGRKAA
                     TKEEAIRFAGEQLVKGGYVEPEYVQAMLDREKLTPTYLGESIAVPHGTVEAKDRVLKT
                     GVVFCQYPEGVRFGEEEDDIARLVIGIAARNNEHIQVITSLTNALDDETVIERLAHTT
                     SVDEVLELLAGRK"
     gene            4412..5560
                     /gene="mtlD"
                     /locus_tag="IRB70_004354"
     CDS             4412..5560
                     /gene="mtlD"
                     /locus_tag="IRB70_004354"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBC0634194.1"
                     /translation="MKALHFGAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARH
                     SYQVHVVGETEQVDTVSGVNAVSSIGDDVVDLIAQVDLVTTAVGPVVLERIAPAIAKG
                     LVKRKEQGNESPLNIIACENMVRGTTQLKGHVMNALPEDAKAWVEEHVGFVDSAVDRI
                     VPPSASATNDPLEVTVETFSEWIVDKTQFKGALPNIPGMELTDNLMAFVERKLFTLNT
                     GHAITAYLGKLAGHQTIRDAILDEKIRAVVKGAMEESGAVLIKRYGFDADKHAAYIRK
                     ILGRFENPYLKDDVERVGRQPLRKLSAGDRLIKPLLGTLEYGLPHKNLIEGIAAAMHF
                     RSEDDPQAQELAALIADKGPQAALAQISGLDANSEVVSEAVTAYKAMQ"
     gene            5560..6147
                     /gene="mtlR"
                     /locus_tag="IRB70_004355"
     CDS             5560..6147
                     /gene="mtlR"
                     /locus_tag="IRB70_004355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol operon repressor MtlR"
                     /protein_id="HBC0634195.1"
                     /translation="MVDQAQDTLRPNNRLSDMQATMEQTQAFENRVLERLNAGKTVRS
                     FLITAVELLTEAVNLLVLQVFRKDDYAVKYAVEPLLDGDGPLGDLSVRLKLIYGLGVI
                     NRQEYEDAELLMALREELNHDGNEYAFTDDEILGPFGELHCVAALPPPPQFEPADSSL
                     YAMQIQRYQQAVRSTMVLSLTELISKISLKKAFQK"
     gene            complement(6158..6367)
                     /locus_tag="IRB70_004356"
     CDS             complement(6158..6367)
                     /locus_tag="IRB70_004356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634196.1"
                     /translation="MGKLGENVPLLIDKAVDFMASSQAFREYLKKLPPRNAIPSGIPD
                     ESVPLYLQRLEYYRQLYRPKQVEEK"
     gene            6650..7012
                     /locus_tag="IRB70_004357"
     CDS             6650..7012
                     /locus_tag="IRB70_004357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibL family ribosome-associated protein"
                     /protein_id="HBC0634197.1"
                     /translation="MKEVEKNEIKRLSDRLDAIRHQQADLSLVEAADKYAELEKEKAT
                     LEAEIARLREVHSQKLSKEAQKLMKMPFQRAITKKEQADMGKLKKSVRGLVVVHPMTA
                     LGREMGLQEMTGFSKTAF"
     gene            7571..8254
                     /locus_tag="IRB70_004358"
     CDS             7571..8254
                     /locus_tag="IRB70_004358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001049680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3251 domain-containing protein"
                     /protein_id="HBC0634198.1"
                     /translation="MNLKKTLLSVLIIVPLCLLAGCDYIEKASKVDDLVTQQELQKSK
                     IEALEKQQELDKRKIEHFEKQQTTIINSTKTLAGVVKAVKDKQDEFVFTEFNPAQTQY
                     FILNNGSVGLAGRVLAIDAVENGSVIRISLVNLLSVPVSNIGFHATWGNERPTDAKAL
                     AKWQQLLFNTTLNSTLQLMPGQWQDINLTLKGVSPNNLKYLKLSINMANLQFDTVQSA
                     ETRQRKNKK"
     gene            8298..>9949
                     /locus_tag="IRB70_004359"
     CDS             8298..>9949
                     /locus_tag="IRB70_004359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001033292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adhesin"
                     /protein_id="HBC0634199.1"
                     /translation="MNKIFKVIWNPATGSYSVASETAKSRGKKSGRSKLLISVLVASG
                     LLSSFGALANNYDGQPTDYGDGSAGDGWVAIGKGAKANTFMNTSGASTALGYDAIAEG
                     EYSSAIGSKTLATGGASMAFGVSARAMGDRSVALGASSVANGDRSMAFGRYAKTNGYT
                     SLAIGDSSLADGEKTIALGNTAKAYEIMSIALGDHANASKEYSMALGASSAASAANAI
                     AVGRNSAAAGVDSLAFGRLSAANAANAIAMGAESKAAENATAVGTNAEANGLNSIALG
                     SGSIADVDNTIALGNQSQAVAAGAIAIGQGNKADGANAIALGNGSITGGVNAIALGQG
                     SYAGLENGTAIGAQASAQGKNSVALGAGSVATDADTVSVGNTTAQRQIVNMAAGDIST
                     TSTDAINGSQLYAISKSVADNLGGGATVNAQGVVTSPNYRLKSGIFGTVGDALTGLDN
                     NTLQWDSLKKAYSAAHGTDTTSTITNVKDGAISDTSKDAVNGSQLKTTNDNVATNTAN
                     ITTNTNSINTLTDSVGDLKDDALLWNGTAFSAAHGTEATSKIT"
BASE COUNT         2669 a         2375 c         2463 g         2442 t
ORIGIN      
        1 agagaaaaat agttgtatac atatattcca tgaacctaca ttgtgatcta taaattaaat
       61 atttttaaat gtgactatca tccttcagat aataaagcca tcatcgcaat agatggaaaa
      121 gcactcctgc tcttttttga ttagagccgt ggcagaggaa caactcatat catcattgcg
      181 atctcgacaa tgtatagtct gatccttcgg cagatcaaga cggataaaaa atccaatgag
      241 ttcacactca tcccgaactt cttaacataa tggatattaa cgaaaaatca tcacagccga
      301 tgaaataata tgcaaaaata attagtcctt gcagggagca aagttccata atctcccccg
      361 cccccctcaa tgatccaaat aaagataatg catccaactg gtcattctta gcagcacctt
      421 ccgcatcacc gaaacatggc tgaaatggtc ggagtaaact gctacctggg cgtaaatgcc
      481 gtcgggtaag gcatcgatat catcgttagg gtccagttca atggttccca gcacaccgtc
      541 cgtgccgggt acgacggtta atgattgcag taccccttgc gcctgatacg aaccgcctgg
      601 cacgacaggt aaaatactag tcagtttgcc gtggaacacc tgcccaggta gcgcgttaaa
      661 caccacttcc gcatcatcgc cgggtttcag acgtaacagc gagttctgcc gaaattgggc
      721 gacaatttgc cgtttttgct cggggatgaa aaccatcacc ggacgcaacg gcaaggcagc
      781 tgcgtatgta cctgggcgga tcagtacctg agtaacgtag ccattgcttg gtgcgcgaat
      841 gacagtctgc tcaaggttat attttgcttc agtaagttgc gctcttaagc tcacaatctg
      901 cgactgctcg ccgttaacca tactgtcgag ctggctctgg atctgcgcct gctccgccac
      961 cgagcctttc accagcgcgt cctgcgcgag gaagttttgc cgcgcatcgt cgatgtcacg
     1021 ttccgagaac ggattcactg ccgcctggct gcctttcagg taacgttgat aatttttaaa
     1081 caggcggtcg cgctccgctg aaacctgggt ggtgttggcc tgcgcttcag tgagctgcgc
     1141 gcgcagcgtc tttatattat gcgtcgccgt catcaggtca gcctgaagtc tgtcaactcg
     1201 cgcctggtaa cgaaccgggt cgagcttaaa aagcacctcg cccttctgaa taagctgatt
     1261 atttttgtcg gtgacttcag taacaattcc cgtcacctgt ggcgtgatgg ggatcgctat
     1321 cactgccttt tgcgcggtaa aagtgtaagg gtggttgtag ttcatcaaca aaatcaaacc
     1381 actcaccaga aacacgcctc ccagcgccgc cgtcgccagc gtccactgat ttaccggaat
     1441 gcggaagatt ttaaagaccg cccacgccag cgccacgtaa gttaaaacaa tcaatagatc
     1501 catatttaga tctccgggaa cgtggaatag tcagtctttt tctcggcggc gagttgatgc
     1561 tccagccggg aaattcggtc agaaagtgcg gcgatttccg ggtcagtcgc tttctcctgc
     1621 gacgcaacat gtgactgcat accccagcca cgctccggtt gatagagcgt cgcccagatc
     1681 cacaggaacg gccagataac atgcagagta aacaggctca cccagcccgc tgtatgaata
     1741 gcgtcggcat gggggtgatt acgctttttg gcaatcagat aagggatgtc atgtatcgcg
     1801 atgattccat aaaaaatcac cagaaagacg aagatcagca ctcccaacgc gaagtagttt
     1861 agaaacatat ctgcctcgga ttcacgttta tcagtgttgt ttttggctgg cagccagatg
     1921 ggagtcgggc tgatattttg acaataatcc gggttggcga ttctcgccat aacaccgaag
     1981 aataattttt agaggtgatg agttgcttag ttacataacg attttatgac gaaggcataa
     2041 catgctgcag atcacatcag gtgaacgccg taagaaaata tcttgtgatt cagatcacaa
     2101 agattcaaca aactaacaaa acaaaaatgt gacattactc acatttaaat gccattttta
     2161 gcgaaaatcg ccgccttgtt gcttttttac acaagagttt tgtgatgcac atcacgtcaa
     2221 ttacctctct accccctata tttatgtgat tcatatcaca caaaaagccg tcgactggac
     2281 agttaaccga ttcagtgcca gatttcgcag tatctacaag gtccggctac ctctgccgcc
     2341 acattaacaa aaaacctcgg gcttccagcc tgcgcgacag caaacataag aaggggtgtt
     2401 tttatgtcat ccgatattaa gatcaaagtg caaagctttg gtcgtttcct cagcaacatg
     2461 gtgatgccaa atatcggcgc gtttatcgcg tggggtatca tcaccgcgtt atttattcca
     2521 acagggtggt taccgaacga aacgctggcg aagctggtcg ggccgatgat cacttatctc
     2581 ctgccactgc tgatcggtta taccggtggt aagctggtag gcggcgaacg tggcggcgta
     2641 gtcggtgcca ttaccaccat gggcgttatc gtcggcgcag acatgccgat gttcctcggt
     2701 tctatgattg caggtccgct gggcggctgg tgcattaagc acttcgaccg ctgggtagac
     2761 ggtaagatca aatccggttt tgaaatgctg gtgaataact tctccgcagg catcatcggg
     2821 atgatcctcg ctattctggc atttctcggc attggcccgg ttgttgaagc cctgtctaaa
     2881 atgctggcgg cgggcgttaa cttcatggtt gtccatgaca tgctgccgct ggcgtctatc
     2941 tttgttgaac cggcgaaaat cctgttcctc aacaacgcca ttaaccacgg tatcttctcg
     3001 ccgctgggta ttcagcagtc ccatgaactg ggtaaatcca tcttcttcct gattgaagct
     3061 aacccaggtc caggtatggg cgtgctgctg gcgtacatgt tctttggtcg tggtagcgct
     3121 aaacagtctg cgggcggtgc ggcaatcatc cacttcctgg ggggtatcca cgaaatctac
     3181 ttcccgtatg tgctgatgaa tccgcgtctg attctggccg ttatcctcgg cggtatgact
     3241 ggcgtattca cgctgactat cctgggcggt gggctggttt ctccggcatc tccgggttct
     3301 atccttgctg tactggcgat gacgccaaaa ggtgcttact tcgctaacat cgcgggtgtg
     3361 tgtgcggcga tggcagtctc cttcgttgtc tctgctattt tgctgaaaac cagcaaagtg
     3421 aaagaagaag atgatattga agctgctgcg cgtcgcgttc aggaaatgaa agctgagtct
     3481 aaaggtgcat ctccgctgtc tgcgggcgat gtgactaacg acctgagcca cgtacgtaaa
     3541 atcatcgttg cctgtgacgc cggtatgggt tccagtgcga tgggcgcagg tgtgctgcgt
     3601 aagaaaattc aggatgcagg tctgtcgcag atttctgtta ctaacagcgc gatcaacaac
     3661 ctgccgccag atgtggacct ggtcatcact caccgtgacc tgaccgaacg cgctatgcgc
     3721 caggttccgc aggcacagca tatttcgctg accaacttcc tcgacagcgg cctgtacacc
     3781 agcctgaccg aacgtctggt tgctgcccag cgccatactg aaaacgaagt aaaagtgaaa
     3841 gacagtctga aagacagctt tgacgattcc agtgctaacc tgttcaagct aggcgcggag
     3901 aacatcttcc tcggtcgcaa agcggccacc aaagaagaag cgattcgttt tgctggcgag
     3961 cagctggtga aaggcggtta cgttgagccg gaatacgttc aggcgatgct ggatcgtgaa
     4021 aaactgaccc cgacttatct gggtgagtct atcgcggtgc cacacggtac ggttgaagca
     4081 aaagatcgcg tactgaaaac gggcgtggtg ttctgccagt acccggaagg cgtgcgcttc
     4141 ggtgaagaag aagatgacat tgcccgtctg gtgattggta ttgctgcccg taacaacgag
     4201 cacattcagg ttatcaccag cctgaccaat gcactggatg atgagactgt catcgagcgt
     4261 ctggcacaca ccaccagcgt ggatgaagtg ctggaattgc tggcaggtcg taagtaatcc
     4321 aatcctaccc tctcctcacg gagagggttt gggtgaggga aaagcctcac cccagccctc
     4381 tcgggtaaaa acattgatga aggttaatac tatgaaagca ttacattttg gcgcaggtaa
     4441 tatcggtcgt ggctttatcg gtaaactgct ggcagacgcg ggtatccaac tgacgtttgc
     4501 cgatgtcaat caggtggtac ttgatgccct gaatgcccgt catagctatc aggttcatgt
     4561 ggttggtgaa accgagcagg tagataccgt ttccggcgtc aatgctgtca gcagcattgg
     4621 tgatgatgtc gttgatctga ttgctcaggt tgatttagtc actaccgccg tgggcccggt
     4681 tgtgctggaa cgtattgccc cggcaatcgc caaagggctg gtgaaacgta aagaacaagg
     4741 taatgaatcc ccgctgaaca tcatcgcttg tgaaaacatg gtccgcggca ccacacagct
     4801 gaaaggacat gtgatgaacg ccctgccgga agatgccaaa gcgtgggtag aagaacacgt
     4861 tggctttgtt gattccgccg ttgaccgcat cgtgccgcct tcggcttctg caaccaacga
     4921 tccgctggaa gtgacggtag aaacattcag cgaatggatt gttgataaaa cccagttcaa
     4981 aggcgcgctg ccgaacatcc caggcatgga gttaaccgac aacctgatgg catttgttga
     5041 gcgtaaactc ttcaccctga atacaggtca tgctataacc gcgtacctcg gaaaactggc
     5101 cggtcatcag accattcgtg atgcgattct cgacgagaaa atccgcgcgg tggtaaaagg
     5161 tgcgatggaa gaaagtggtg cagtattgat caagcgctac ggctttgacg cagacaaaca
     5221 tgcggcgtac atccggaaaa tcctcggtcg tttcgagaac ccgtacctga aagatgatgt
     5281 agagcgcgta ggccgtcagc cgctgcgtaa actgagtgct ggcgaccgtc taatcaagcc
     5341 actgctcgga acgctggaat atggtctgcc acataaaaac ctgattgaag gtattgccgc
     5401 tgcaatgcac ttccgcagtg aagatgatcc gcaggctcag gaactggcag cactgatcgc
     5461 tgacaaaggt ccgcaggcgg cgctggcaca gatttccggt cttgatgcca acagcgaggt
     5521 tgtatccgag gcggtaaccg cttataaagc aatgcaataa tggtggacca ggcgcaggat
     5581 accctgcgcc cgaataacag attgtcagat atgcaggcaa caatggaaca aacccaggcc
     5641 tttgaaaacc gtgtgcttga gcgtctgaat gctggcaaaa ccgtgcgaag ctttctgatc
     5701 accgccgtcg agcttttgac cgaggcggta aatcttctgg tgcttcaggt attccgcaaa
     5761 gacgattacg cggtgaagta tgctgtagaa ccgttactcg acggcgatgg tccgctgggc
     5821 gatctttctg tgcgtttaaa actcatttac gggttgggcg tcattaaccg ccaggaatac
     5881 gaagatgcgg aactgctgat ggcattgcgt gaagagctaa atcacgacgg caacgagtac
     5941 gcttttaccg acgacgaaat acttggaccc tttggtgaac tgcattgcgt ggcggcgtta
     6001 ccaccgccgc cacagtttga acctgcagac tccagtttgt atgcaatgca aattcagcgt
     6061 taccaacagg ctgtgcgatc aacaatggtc ctttcactga cagagctgat ttccaaaatc
     6121 agcttaaaaa aagcctttca aaagtaagta ctttcgctta cttctcctct acctgtttcg
     6181 gacgataaag ctgacgataa tactccagac gttgtagata taacggcacg ctttcatcag
     6241 gtattccgga cggaatcgcg ttacggggag gtagtttttt cagatactcc cggaacgcct
     6301 ggctcgatgc catgaaatct acggctttat cgataagaag cggaacgttt tcacctaatt
     6361 tgcccatgat gatatctccg tattaccccg cgccgggaat gcgcggccgc caattttagt
     6421 ttagatcccg gtataaatga cattaaggaa aacgtgctca atcctcaata atcatccgtt
     6481 ttattaacta tcttttttct ttaaatttct taattaatca ataaattgcg tagtttttaa
     6541 gcatgttaat gtttacgtta tagaactatt gcaatgtcat cagttgtgaa caaagcacct
     6601 ggtcgcgcat actaggggct ataaatttat ctttatcaga agccatcaca tgaaagaagt
     6661 cgaaaaaaac gaaatcaaac gtctcagcga tcgcctggac gccatccgtc accagcaggc
     6721 cgatctgtcg ctggttgaag ccgcagacaa atatgccgaa ctggaaaaag agaaagccac
     6781 tctggaagca gaaattgctc gcctgcgcga agttcacagc cagaaactca gcaaagaagc
     6841 gcagaaactg atgaagatgc cgttccagcg tgcaatcacc aaaaaagagc aggctgatat
     6901 gggcaaactg aaaaaaagtg ttcgcggact ggtggttgtg cacccaatga ccgcgctggg
     6961 ccgtgaaatg ggcctgcaag agatgacagg gttctcaaag actgcgtttt aagttccttt
     7021 ctcgtcgctg taatcacagc ctctcacgat ttactcgctc ctgctggcac atgcaggagc
     7081 ctgtttcaga gatcgaatat ttgtaacgtt cttaacatta tatattcaac tccacctaca
     7141 cttctgagcg atctgagcag gctaaattct gaaaagcagg tacaaattaa ataatgatgt
     7201 atcaatatca acaatgaatt accgcatatc aatgcttgaa acataattaa ttatttaaat
     7261 ttttctatca gcatcgcaaa cttcgcaata aaacatcact caactgaata tttacctttc
     7321 cctgccctgg gcctttatcc ggtgaaacat ttgacattga ttgacaccga tcattaaaat
     7381 ccgcgcgatt aatattattg gctacaaacc gaaattgttt gacacttaat aacatattcg
     7441 cacaaccgat taatacaaaa attctctaac aaatttattt gtcggatatg ctccactcca
     7501 atcattcata aaaaaaatga ttgtgccgta attatcaact gtatcgggat tatgaaaagg
     7561 aattcatcct atgaacctaa agaaaacact gttaagcgtg ttaataatag tgcctctctg
     7621 cttattggca gggtgtgact atattgaaaa agcgagtaag gtcgacgacc tcgttacaca
     7681 gcaagagttg caaaaaagca aaattgaggc gcttgagaaa caacaggaac tcgataagcg
     7741 aaagatagaa cattttgaaa aacaacaaac tactatcata aatagtacca agacgctcgc
     7801 tggcgtggtg aaggcggtta aagacaaaca ggacgaattt gtctttacag aatttaaccc
     7861 ggcacaaacc caatacttca ttttaaataa cggctctgtt ggtttggcag gccgggtgct
     7921 ggctattgat gcagttgaaa atggcagcgt tattcgtatt tcgctggtta atttattaag
     7981 cgttcccgta tcaaatattg gctttcatgc gacatggggc aatgaaaggc ccaccgatgc
     8041 caaagctctg gcaaagtggc aacaattact tttcaacacc acactgaatt ccactctgca
     8101 attaatgcct ggtcaatggc aagacattaa tctgacatta aaaggcgttt cgcctaataa
     8161 cctgaagtat ctgaagttgt ccatcaatat ggccaatctc cagttcgaca ctgttcaatc
     8221 tgctgaaact cggcagcgaa aaaacaaaaa ataaatgcag cttctgcgct tatatcaagg
     8281 aatagagagc atcaataatg aacaaaattt ttaaagttat ctggaatcca gcgacgggca
     8341 gttacagcgt tgccagcgaa acggcgaaga gccgtggtaa aaaaagcggg cgcagtaagc
     8401 tgttaatttc tgtactagtt gcgagtgggt tgttgtcgtc gtttggagcg ttagctaata
     8461 actacgacgg gcagccaact gattatggcg atggctcagc aggtgacggc tgggttgcta
     8521 tcggtaaagg ggcaaaagca aataccttta tgaacactag tggcgcgagt acagctttag
     8581 gatatgacgc gatagccgaa ggtgagtaca gttctgccat cgggtcaaaa acccttgcaa
     8641 ctggtggagc atccatggcg ttcggggtta gtgcaagagc aatgggtgac agaagtgtcg
     8701 cgctgggtgc atcgtcagta gcaaatggcg atcgttcgat ggcttttggt cgttacgcaa
     8761 agacgaatgg ttatacatct cttgctattg gggactcctc ccttgccgat ggtgaaaaaa
     8821 ctattgcgtt aggaaatacg gctaaagctt acgaaattat gagcatcgcc ctcggtgatc
     8881 atgccaatgc gtcaaaagaa tattcaatgg cgctgggtgc aagtagtgcc gcatctgcgg
     8941 ctaacgcgat tgcagtaggc cgcaacagtg ctgcagctgg cgtagacagc ctcgcattcg
     9001 gtagactatc cgccgccaac gccgcaaacg cgattgctat gggtgcagag agcaaagctg
     9061 ctgaaaatgc gacggcagtt ggtactaacg cggaggcaaa tggacttaat agtatcgcgt
     9121 tgggctccgg cagtattgca gatgtcgaca acactattgc tctgggcaat caaagtcagg
     9181 cagtagcggc tggcgcaatt gccatcggtc aagggaataa agctgacggc gcaaatgcta
     9241 tcgcgctggg taatggtagt attacaggtg gtgtaaatgc tattgctctt ggacaaggca
     9301 gttatgccgg tttagaaaat ggcactgcaa ttggtgctca agccagtgct caggggaaaa
     9361 attcagttgc tctgggtgct ggttctgtag cgactgacgc ggatactgtt tctgtgggta
     9421 acacaacagc tcagcgacaa attgtcaata tggcagcagg tgatatcagc actaccagta
     9481 ctgatgccat caatggatca cagctttatg ctatcagtaa gtcagtagcg gacaatcttg
     9541 gtgggggggc taccgtcaat gcgcaaggcg tcgttacttc cccaaattac aggctgaaaa
     9601 gtggtatttt cggcactgtt ggcgacgcct taacgggcct ggacaataat acgttacaat
     9661 gggactccct taaaaaggca tatagtgcgg cacatggtac agatactacc agtaccatca
     9721 ccaacgttaa agacggcgct atttctgata ccagtaagga tgcggttaac ggttctcagc
     9781 tgaaaaccac caacgataac gtagcgacca atactgccaa tatcaccacc aacactaaca
     9841 gtatcaatac cctgacggat tccgttggcg accttaaaga cgatgccctg ctgtggaatg
     9901 gcaccgcgtt cagcgccgcg cacggcaccg aagccaccag caaaatcac
//
LOCUS       DADXDL010000130         9899 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.130, whole genome shotgun sequence.
ACCESSION   DADXDL010000130 DADXDL010000000
VERSION     DADXDL010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9899)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9899)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9899
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.130"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..681)
                     /gene="intI1"
                     /locus_tag="IRB70_004360"
     CDS             complement(<1..681)
                     /gene="intI1"
                     /locus_tag="IRB70_004360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1 integron integrase IntI1"
                     /protein_id="HBC0634200.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAFLSWLANERKVSVSTHRQALAALLFFYGKVLCTDLPWLQ
                     EIGRPRPSRRLPVVLTPDEVVRILGFLEGEHRLFAQLLYGTGMRISEGLQLRVKDLDF
                     DHGTIIVREGKGSKDRALMLPESLAPSLREQLSRARAWWLKDQAEGRSGVALPDALER
                     KYPRAGHSW"
     gene            839..1312
                     /locus_tag="IRB70_004361"
     CDS             839..1312
                     /locus_tag="IRB70_004361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /protein_id="HBC0634201.1"
                     /translation="MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVG
                     RKTFDSMGVLPNRKYAVVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQI
                     YNSLIEKADIIHLSTVHVEVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG"
     gene            1443..2231
                     /locus_tag="IRB70_004362"
     CDS             1443..2231
                     /locus_tag="IRB70_004362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="HBC0634202.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKP
                     DSDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYP
                     ARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKE
                     HFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPA
                     EHRPLICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
     gene            2437..2784
                     /locus_tag="IRB70_004363"
     CDS             2437..2784
                     /locus_tag="IRB70_004363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="HBC0634203.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     gene            2778..3617
                     /gene="sul1"
                     /locus_tag="IRB70_004364"
     CDS             2778..3617
                     /gene="sul1"
                     /locus_tag="IRB70_004364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /protein_id="HBC0634204.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     gene            3745..3948
                     /locus_tag="IRB70_004365"
     CDS             3745..3948
                     /locus_tag="IRB70_004365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634205.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLGIASENGK"
     gene            4104..5309
                     /gene="chrA"
                     /locus_tag="IRB70_004366"
     CDS             4104..5309
                     /gene="chrA"
                     /locus_tag="IRB70_004366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004896675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate efflux transporter"
                     /protein_id="HBC0634206.1"
                     /translation="MTNNPTDDSRPWSVFLIFLRLGLTSFGGPIAHLGYFRAEFVTRR
                     RWLSERSYADLVALCQFLPGPASSQVGIAVGLSRAGYSGALAAWAGFTLPSAIALILF
                     ALGISSYGDYVSQGALHGLKVVAVAVVAQAVWGMARNLCTDGLRVTIMAIATCVVLLV
                     PSAWGQVGVIAIAGIAGRLLFKPAKVVEHDPLPITVSHRAGVLWLSLFFVLLIGLPVL
                     AELMPSQTMAMVDSFYRVGSLVFGGGHVVLPLLQAEVVPSGWVNNESFLAGYGAAQAV
                     PGPLFTFAAFLGASMNTAPSGWIGGIVCLLAIFAPSFLLVVGSMPFWERLRRNTGIQA
                     ALAGINAAVVGLLLAALYQPVWTSAIFQPQDFGLALVALVALMFWKLPPWLVVLGSGA
                     AGWLLSVAL"
     gene            5320..5625
                     /locus_tag="IRB70_004367"
     CDS             5320..5625
                     /locus_tag="IRB70_004367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000130000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0634207.1"
                     /translation="MTDKDLYGGLIRLHILHHAAEEPVFGLGIIEELRRHGYEMSAGT
                     VYPMLHGLEKKGYLTSRHERTGRRERRVYDITEQGRTALADAKTKVKELFGELVEGG"
     gene            5669..5734
                     /locus_tag="IRB70_004368"
                     /pseudo
     CDS             5669..5734
                     /locus_tag="IRB70_004368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229646.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EAL domain-containing protein"
     gene            5852..6616
                     /locus_tag="IRB70_004369"
     CDS             5852..6616
                     /locus_tag="IRB70_004369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element IS6100 family transposase"
                     /protein_id="HBC0634208.1"
                     /translation="MTDFKWRHFQGDVILWAVRWYCRYPISYRDLEEMLAERGISVDH
                     TTIYRWVQCYAPEMEKRLRWFWRRGFDPSWRLDETYVKVRGKWTYLYRAVDKRGDTID
                     FYLSPTRSAKAAKRFLGKALRGLKHWEKPATLNTDKAPSYGAAITELKREGKLDRETA
                     HRQVKYLNNVIEADHGKLKILIKPVRGFKSIPTAYATIKGFEVMRALRKGQARPWCLQ
                     PGIRGEVRLVERAFGIGPSALTEAMGMLNHHFAAAA"
     gene            complement(7109..7693)
                     /locus_tag="IRB70_004370"
     CDS             complement(7109..7693)
                     /locus_tag="IRB70_004370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBC0634209.1"
                     /translation="MPRPKLKSDDEVLEAATVVLKRCGPIEFTLSGVAKEVGLSRAAL
                     IQRFTNRDTLLVRMMERGVEQVRHYLNAIPIGAGPQGLWEFLQVLVRSMNTRNDFSVN
                     YLISWYELQVPELRTLAIQRNRAVVEGIRKRLPPGAPAAAELLLHSVIAGATMQWAVD
                     PDGELADHVLAQIAAILCLMFPEHDDFQLLQAHA"
     gene            complement(7693..8931)
                     /locus_tag="IRB70_004371"
     CDS             complement(7693..8931)
                     /locus_tag="IRB70_004371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0634210.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWA
                     GATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTG
                     LIACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGA
                     AIGLLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLWSEPLL
                     RPLFGIVMIFVGIVGANGSVIMPALFVDAGRQVAELGLFSSMMGAGGLLGIAIHASVG
                     ARISAQNWLAVAFCGSAVGSLLLSQLPGVPVLMLLGALVGLLTGSVSPILNAAIYNRT
                     PPELLGRVLGTVSAVMLSASPMVMLAAGAFVDLAGPLPGLVVSAVFAGLVALLSLRLQ
                     FATMAAAATASAPTHTEGEH"
     gene            complement(8928..9833)
                     /locus_tag="IRB70_004372"
     CDS             complement(8928..9833)
                     /locus_tag="IRB70_004372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HBC0634211.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAE"
BASE COUNT         2055 a         2859 c         2919 g         2066 t
ORIGIN      
        1 ccaggaatgc ccggcgcgcg gatacttccg ctcaagggcg tcgggaagcg caacgccgct
       61 gcggccctcg gcctggtcct tcagccacca tgcccgtgca cgcgacagct gctcgcgcag
      121 gctgggtgcc aagctctcgg gtaacatcaa ggcccgatcc ttggagccct tgccctcccg
      181 cacgatgatc gtgccgtgat cgaaatccag atccttgacc cgcagttgca aaccctcact
      241 gatccgcatg cccgttccat acagaagctg ggcgaacaaa cgatgctcgc cttccagaaa
      301 accgaggatg cgaaccactt catccggggt cagcaccacc ggcaagcgcc gcgacggccg
      361 aggtcttccg atctcctgaa gccagggcag atccgtgcac agcaccttgc cgtagaagaa
      421 cagcaaggcc gccaatgcct gacgatgcgt ggagaccgaa accttgcgct cgttcgccag
      481 ccaggacaga aatgcctcga cttcgctgct gcccaaggtt gccgggtgac gcacaccgtg
      541 gaaacggatg aaggcacgaa cccagtggac ataagcctgt tcggttcgta aactgtaatg
      601 caagtagcgt atgcgctcac gcaactggtc cagaaccttg accgaacgca gcggtggtaa
      661 cggcgcagtg gcggttttca tggcttgtta tgactgtttt tttgtacagt ctatgcctcg
      721 ggcatccaag cagcaagcgc gttacgccgt gggtcgatgt ttgatgttat ggagcagcaa
      781 cgatgttacg cagcagggca gtcgccctaa aacaaagtta gccattaagg gagttaaatt
      841 gaaaatatca ttgatttctg cagtgtcaga aaatggcgta atcggtagtg gtcctgatat
      901 cccgtggtca gtaaaaggtg agcaactact ctttaaagcg ctcacatata atcaatggct
      961 ccttgtcgga agaaaaacat ttgactctat gggtgttctt ccaaatcgca aatatgcagt
     1021 agtgtcaaag aacggaattt caagctcaaa tgaaaacgtc ctagtttttc cttcaataga
     1081 aaatgctttg aaagagctat caaaagttac agatcatgta tatgtctctg gcgggggtca
     1141 aatctataat agccttattg aaaaagcaga tataattcat ttgtctactg ttcacgttga
     1201 agtcgaaggt gatatcaaat tccctataat gcctgagaat ttcaatttgg tttttgaaca
     1261 gttttttatg tctaatataa attatacata ccagatttgg aaaaaaggct aacaatgcgt
     1321 tgcagcacca gtcgcttcgc tccttggaca gcttttaagt cgcgtctttg tggttttgct
     1381 gcgcaaaagt attccacaaa gccgcaactt aaaagctgcc gctgaactta acgttaggca
     1441 tcatgggtga atttttccct gcacaagttt tcaagcagct gtcccacgct cgcgcggtga
     1501 tcgagcgcca tctggctgcg acactggaca caatccacct gttcggatct gcgatcgatg
     1561 gagggctgaa gccggacagc gacatagact tgctcgtgac cgtcagcgcc gcacctaacg
     1621 attcgctccg gcaggcgcta atgctcgatt tgctgaaagt ctcatcaccg ccaggcgatg
     1681 gcggaacatg gcgaccgctg gagctaactg ttgtcgctcg aagcgaagta gtgccttggc
     1741 gctatccggc gcggcgtgag cttcagttcg gtgagtggct ccgccacgac atcctttccg
     1801 gaacgttcga gcctgccgtt ctggatcacg atcttgcgat tttgctgacc aaggcgaggc
     1861 aacacagcct tgcgcttcta ggcccatccg cagccacgtt tttcgagccg gtgccgaagg
     1921 agcatttctc caaggcgctt ttcgacacta ttgcccagtg gaatgcagag tcggattgga
     1981 agggtgacga gcggaacgtc gttcttgctc ttgctcgcat ttggtacagc gcttcaactg
     2041 gtctcattgc tcctaaggac gttgctgccg catgggtatc ggagcgtttg cctgccgagc
     2101 atcggcccct catctgcaag gcacgcgcgg cgtacctggg tagcgaggac gacgacctag
     2161 caatgcgcgt cgaagagacg gccgcgttcg ttcgatatgc caaagcaacg attgagagaa
     2221 tcttgcgttg agcggcatgt gcgaaaagtg catcgacccg cgccgagggc atctgatgcc
     2281 taactcggcg ttcaagcgga cgggctgcgc ccgccgctca actatgcgtt agatgcacta
     2341 agcacataat tgctcacagc caaactatca ggtcaagtct gcttttatta tttttaagcg
     2401 tgcataataa gccctacaca aattgggaga tatatcatga aaggctggct ttttcttgtt
     2461 atcgcaatag ttggcgaagt aatcgcaaca tccgcattaa aatctagcga gggctttact
     2521 aagcttgccc cttccgccgt tgtcataatc ggttatggca tcgcatttta ttttctttct
     2581 ctggttctga aatccatccc tgtcggtgtt gcttatgcag tctggtcggg actcggcgtc
     2641 gtcataatta cagccattgc ctggttgctt catgggcaaa agcttgatgc gtggggcttt
     2701 gtaggtatgg ggctcataat tgctgccttt ttgctcgccc gatccccatc gtggaagtcg
     2761 ctgcggaggc cgacgccatg gtgacggtgt tcggcattct gaatctcacc gaggactcct
     2821 tcttcgatga gagccggcgg ctagaccccg ccggcgctgt caccgcggcg atcgaaatgc
     2881 tgcgagtcgg atcagacgtc gtggatgtcg gaccggccgc cagccatccg gacgcgaggc
     2941 ctgtatcgcc ggccgatgag atcagacgta ttgcgccgct cttagacgcc ctgtccgatc
     3001 agatgcaccg tgtttcaatc gacagcttcc aaccggaaac ccagcgctat gcgctcaagc
     3061 gcggcgtggg ctacctgaac gatatccaag gatttcctga ccctgcgctc tatcccgata
     3121 ttgctgaggc ggactgcagg ctggtggtta tgcactcagc gcagcgggat ggcatcgcca
     3181 cccgcaccgg tcaccttcga cccgaagacg cgctcgacga gattgtgcgg ttcttcgagg
     3241 cgcgggtttc cgccttgcga cggagcgggg tcgctgccga ccggctcatc ctcgatccgg
     3301 ggatgggatt tttcttgagc cccgcaccgg aaacatcgct gcacgtgctg tcgaaccttc
     3361 aaaagctgaa gtcggcgttg gggcttccgc tattggtctc ggtgtcgcgg aaatccttct
     3421 tgggcgccac cgttggcctt cctgtaaagg atctgggtcc agcgagcctt gcggcggaac
     3481 ttcacgcgat cggcaatggc gctgactacg tccgcaccca cgcgcctgga gatctgcgaa
     3541 gcgcaatcac cttctcggaa accctcgcga aatttcgcag tcgcgacgcc agagaccgag
     3601 ggttagatca tgcctagcat tcaccttccg gccgcccgct agcggaccct ggtcaggttc
     3661 cgcgaaggtg ggcgcagaca tgctgggctc gtcaggatca aactgcacta tgaggcggcg
     3721 gttcataccg cgccagggga gcgaatggac agcgaggagc ctccgaacgt tcgggtcgcc
     3781 tgctcgggtg atatcgacga ggttgtgcgg ctgatgcacg acgctgcggc gtggatgtcc
     3841 gccaagggaa cgcccgcctg ggacgtcgcg cggatcgacc ggacattcgc ggagaccttc
     3901 gtcctgagat ccgagctcct agggatcgcc tcagaaaacg gaaaataaag cacgctaagc
     3961 cgtaagtaag cgtgctcctg tgaaagccac agctaaaact gcgtagtaca catagaggta
     4021 tttttttcta gatttatatc gaatttcgtt atcgaatttc gcttattatt gatcaactcg
     4081 ttgcagatca tgaaggcgaa agtatgacga ataaccctac cgatgacagc agaccatggt
     4141 cggtctttct tatttttctg cggcttggat tgacatcttt tggcggcccc attgcgcact
     4201 tgggctactt ccgcgccgaa tttgtcacac ggcggcgctg gctctccgaa cggagctatg
     4261 ctgacttggt cgcgctttgt cagttcttgc cagggcctgc aagcagccag gtcggcatag
     4321 cggtaggact gtctcgggct ggatacagcg gggcgctggc tgcttgggct ggcttcacgc
     4381 tgccgtctgc catagccttg atcctttttg cgctcggcat ctccagctat ggcgattacg
     4441 tctcgcaggg cgcgttgcat ggcttaaaag tggtggctgt ggccgtggtc gctcaagcag
     4501 tatggggcat ggcgcgtaac ctatgcacgg atgggctgcg agtcaccatc atggcaattg
     4561 ctacctgcgt cgttttactt gtgccgtccg cgtggggaca ggttggcgtg attgctatcg
     4621 caggcatcgc aggccggtta ttgttcaagc cagcgaaagt tgttgagcat gaccccctac
     4681 ctatcacggt cagtcaccgg gccggcgtgc tttggctctc gctgttcttt gtcttgctga
     4741 ttggcctgcc ggtgttggcc gaactgatgc caagtcaaac catggcaatg gtggattcct
     4801 tctatcgtgt cggatcactg gtgttcggcg gtggtcacgt tgtgctgcca ttactgcaag
     4861 ccgaagtggt gccctccggc tgggtcaaca atgaatcctt tctcgcgggg tacggggcag
     4921 ctcaagcggt gcccggccct ttgttcacgt tcgccgcgtt tcttggtgcc tcgatgaaca
     4981 ccgccccgtc gggctggatc ggcggcattg tgtgtctgct ggctatcttc gcgccctcgt
     5041 tcttgctggt cgtcggatca atgccatttt gggagcgttt gcgccgcaat acaggcatcc
     5101 aagctgcgct ggccgggatc aatgccgctg tagtcggctt gctgctggcc gcgctgtatc
     5161 agcctgtatg gactagcgcc atctttcagc cgcaagactt cggcttggca ttagttgccc
     5221 ttgtcgcact tatgttctgg aagctcccgc cgtggctggt tgtcctcggt agcggtgcag
     5281 ctgggtggct gttgagcgtc gctctgtgag gcacaaaaaa tgactgacaa agacctctac
     5341 ggcggtttga tccgcctgca catccttcac catgcagccg aggaacctgt ctttgggctg
     5401 gggatcatcg aagagctacg ccgacacggc tacgagatga gcgctggcac cgtgtacccg
     5461 atgctgcacg gcctggaaaa aaaaggctat ctgacctcac gccacgaacg caccgggcga
     5521 cgtgaacggc gtgtttatga catcactgaa caaggcagaa ctgcacttgc tgatgcgaaa
     5581 acaaaggtca aggagctgtt cggagagttg gtagaaggtg gttgagtttt tgcttctatg
     5641 tcaggttgag ctatacccta actggattgt cattttcaga agacgactgc accagttgat
     5701 tgggcgtaat ggctgttgtg cagccagctc ctgacagttc aatatcagaa gtgatctgca
     5761 ccaatctcga ctatgctcaa tactcgtgtg ggctctgttg caaaaatcgt gaagcttgag
     5821 catgcttggc ggagattgga cggacggaac gatgacggat ttcaagtggc gccatttcca
     5881 gggtgatgtg atcctgtggg cggtgcgctg gtattgtcgc tatccgatca gctatcgcga
     5941 ccttgaggaa atgctggcgg aacgcggcat ttcggtcgac catacgacga tctatcgctg
     6001 ggtccagtgc tacgccccgg agatggagaa gcggctgcgc tggttctggc ggcgtggctt
     6061 tgatccgagc tggcgcctgg atgaaaccta cgtcaaggtg cggggcaagt ggacctacct
     6121 gtaccgggca gtcgacaagc ggggcgacac gatcgatttc tacctgtcgc cgacccgcag
     6181 cgccaaggca gcgaagcggt tcctgggcaa ggccctgcga ggcctgaagc actgggaaaa
     6241 gcctgccacg ctcaataccg acaaagcgcc gagctatggt gcagcgatca ccgaattgaa
     6301 gcgcgaagga aagctggacc gggagacggc ccaccggcag gtgaagtatc tcaataacgt
     6361 gatcgaggcc gatcacggaa agctcaagat actgatcaag ccggtgcgcg gtttcaaatc
     6421 gatccccacg gcctatgcca cgatcaaggg attcgaagtc atgcgagccc tgcgcaaagg
     6481 acaggctcgc ccctggtgcc tgcagcccgg catcaggggc gaggtgcgcc ttgtggagag
     6541 agcttttggc attgggccct cggcgctgac ggaggccatg ggcatgctca accaccattt
     6601 cgcagcagcc gcctgatcgg cgcagagcga cagcctacct ctgactgccg ccaatctttg
     6661 caacagagcc cgccgtgcta gtctgctcgg tgatggtgga gtgaagccaa cccgcaatcg
     6721 ggttatgaat ctgcatcgcg attcgcaatc agctgtctct tgagcatgtc gaactcctgc
     6781 gatgttatct cgccgtgctc gtgctgctac accaacttgt ccaactcatc cgccacaccg
     6841 ctccccacca cctgcgatgg ccaggttgtt tgctgggcgc attggcggag tatcgtctcg
     6901 acccgggaca cccacaccgg cacaacctta cgggagtgat tcactgtcaa agaatcggcc
     6961 cggtgctctg acgcaagtat cgggatggtc accatttgta agccgtagac ctgagtggtg
     7021 atcaagactt cgataccacc gaccgtaccg gtactaatcg acgacggtcg tgttcgtcgc
     7081 ctgccgcagg gactctgcac acctccgttt acgcatgtgc ctggaggagt tggaaatcgt
     7141 cgtgttcggg aaacattaaa cacaggatgg cagcgatctg agccagcaca tgatcagcta
     7201 gctcaccatc cggatcgacg gcccactgca tcgtcgcgcc agcgatgacc gagtgcagga
     7261 gcaactcagc tgccgcagga gcacctgggg gcagtcgctt gcggatcccc tccaccaccg
     7321 cgcggttccg ctggatcgca agcgtgcgta gctccggcac ctggagctcg taccaggaga
     7381 tgagatagtt caccgagaag tcgttgcgag tgttcatgct ccgaacgagc acctgcaaaa
     7441 attcccagag cccttgcggc cctgcgccta tcggtatcgc attcaggtaa tgccgcacct
     7501 gctcgacgcc gcgctccatc atcctcacca gcagcgtatc gcggttggtg aagcgctgga
     7561 ttaacgctgc gcgggagagc cccacctcct ttgctactcc gctgagcgtg aactctatgg
     7621 gaccgcaacg cttcagcact acggtggcgg cctcgagtac ctcgtcatcg gacttgagct
     7681 tggggcgggg catcagtgtt caccttctgt atgggttggg gcggaggctg tggctgccgc
     7741 cgccattgta gcaaattgaa gacggagcga gagtagagcc acgagccccg caaacacggc
     7801 cgatacaacg aggccaggga gcggaccagc aaggtcgaca aacgcgccgg ccgcaagcat
     7861 aaccatgggc gaggctgaca gcatcaccgc cgagaccgtg ccgagtaccc ggccgagaag
     7921 ttctggcggc gtgcggttgt agatggcagc gttgagaatg ggagagactg agccggtcag
     7981 cagtcccacg agcgcgccca acaacatcag caccggcacg cctggcaact gtgaaagcag
     8041 aagcgagccc accgcagagc cacaaaatgc caccgccagc cagttctgcg ctgatatccg
     8101 ggcgccgacc gacgcatgaa tggcaatgcc aaggagacca ccagccccca tcattgagga
     8161 gaacagcccg agctctgcta cttggcgtcc tgcatctaca aacagcgcag gcatgatgac
     8221 gctgccgttg gcgccaacga tgcccacgaa gatcatcact ataccaaaga gagggcgcag
     8281 caggggttcg ctccagagaa aagcgacgcc ggcgcgcatg gagagagtcg ccgtcgtggt
     8341 catcgtccga gcggcacgcg cgggaagcac ccacgcgccg agcagacctg caaggacgga
     8401 gcagaacgcc gtcagcccga gcgttggcgc agcgccaagc aggccgattg cggccccccc
     8461 aagggccggg ccacctagaa tcgcgacgtt cccgatcacc gctttcagtg acgagacgcg
     8521 ctcaacggag agcccggcga cgtggccgag tttgggcagc tcactgtcct gcgcggccat
     8581 accgggtgcg tcgaacgcgg caccgagcac cacgcaagcg atcagcccag tgttcgagag
     8641 ggcgccaacg gcatcgagca gtgggatgct cgccatggcc acgccgccca ccacacccga
     8701 gatcaatgcg acgggcgcgc gcccgaaccg atcgacgagg ccaccaccaa cccacgcgcc
     8761 gatgatggtc gcgatgacgc tgctagcggc cgtggcgccc gcccaggccg cgctctttgt
     8821 atgagacagg acgaaccatg gaagcgcgag ggccgccacc gcgttgccga tccggaagag
     8881 aaaggtcgcc gcgaacagcg tcgcgagcgg gctatatcga cgttcgctca ttccgctgcg
     8941 gcgagctgcg ccttcgccgc agcgaggtac tcttcgttac ccgagtcgag ggcgaagagt
     9001 gcgtaggtga ccgccccgaa cgcaaggcgc tccgcgatgt ggtgggcgag ccgcggccac
     9061 acccggccac cggccgcttc atacgtgagg aggagcttcg cgagcccctc ttcaccaaag
     9121 accataaggt gcgcggccat gtcgatggca gggtcatcaa cgcgggcctc gctccagtcg
     9181 atcatcccgc tgacgcgctc cgtgttgtcg atgagcacat ggcccacgta gagatcgcca
     9241 tgcaccacca cggagaaatc tggccacgac gaatcgtcgt cgagccagcg ctgccaccgg
     9301 tggaggcgct tgtcgttcac cacgaactcg cgtcggacgc ggtcaacgtc gtcggccacc
     9361 ttctgacggg cctgcgtcgg tgtacggatg agcatccccg catccacggc ggcggaaatg
     9421 gggacggcat gcagggcggc gagcgcggtc gcgaagctct ccgcgaagac ctccgagtcc
     9481 tgcggcacga cccagtcggg cgtggacgaa ccaggctgga tgaccatcgc agtcgagtct
     9541 tcgagcatgg gataggcaac gagctcggcg ttggccacgc gccagtccgg caccgcgaac
     9601 ggcaggcgat tcttgagcat tgccagcacc cgcgcctctg gttcgacctt cgcgcttacc
     9661 tcggctcggc gcgggatgcg cagcacccac cgacgtccat cgtcgacggt ggcgatcacg
     9721 atcctatagt cgagcccaag ctcattgaca gtcagcgggc catggagctt gagcccatgt
     9781 cgggctgcaa gtgcgtacag ttgggaggta tcggcggtcg tgactacggt catgattcac
     9841 tcctgagggc ttgacgggtt tagccaccta aatgtaacag tcacgtcggt tatattcaa
//
LOCUS       DADXDL010000131         9880 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.131, whole genome shotgun sequence.
ACCESSION   DADXDL010000131 DADXDL010000000
VERSION     DADXDL010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9880)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9880)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9880
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.131"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1306)
                     /gene="xanQ"
                     /locus_tag="IRB70_004373"
     CDS             complement(<1..1306)
                     /gene="xanQ"
                     /locus_tag="IRB70_004373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417358.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine/proton symporter XanQ"
                     /protein_id="HBC0634212.1"
                     /translation="MSDINHAGSDLIFELEDRPPFHQALVGAITHLLAIFVPMVTPAL
                     IVGATLQLSAETTAYLVSMAMIASGIGTWLQVNRYGIVGSGLLSIQSVNFSFVTVMIA
                     LGSSMKSDGFHEELIMSSLLGVSFVGAFLVVGSSFILPYLRRVITPTVSGIVVLMIGL
                     SLIKVGIIDFGGGFAAKSSGTFGNYEHLGVGLLVLIVVIGFNCCRSPLLRMGGIAIGL
                     CVGYIASLCLGMVDFSSMRNLPLITIPHPFKYGFSFSFHQFLVVGTIYLLSVLEAVGD
                     ITATAMVSRRPIQGEEYQSRLKGGVLADGLVSVIASAVGSLPLTTFAQNNGVIQMTGV
                     ASRYVGRTIAVMLVILGLFPMIGGFFTTIPSAVLGGAMTLMFSMIAIAGIRIIITNGL
                     KRRETLIVATSLGLGLGVSYDPEIFKILPASIYVLVENPICAG"
     gene            complement(1471..4341)
                     /locus_tag="IRB70_004374"
     CDS             complement(1471..4341)
                     /locus_tag="IRB70_004374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     Mo/Fe-S-binding subunit"
                     /protein_id="HBC0634213.1"
                     /translation="MIIHFTLNGAPQELTVNPGENVQKLLFNMGMHSVRNSDDGFGFA
                     GSDAIIFNGNIVNASLLIAAQLEKADIRTAESLGKWNELSLVQQAMVDVGVVQSGYND
                     PAAALIITDLLDRIAAPTREEIDDALSGLFSRDAGWQQYYQVIELAVARKNNPQATID
                     IAPTFRDDLEVIGKHYPKTDAAKMVQAKPCYVEDRVTADACVIKMLRSPHAHALITHL
                     DVSKAEALPGVVHVITHLNCPDIYYTPGGQSAPEPSPLDRRMFGKKMRHVGDRVAAVV
                     AESEDIALEALKLIDVEYEVLKPVMSIDEAMAEDAPVVHDEPVVYVAGAPDTLEDDNS
                     HAAQRGEHMIINFPIGSRPRKNIAASIHGHIGDMDKGFADADVIIERTYNSTQAQQCP
                     TETHICFTRMDGDRLVIHASTQVPWHLRRQVARLVGMKQHKVHVIKERVGGGFGSKQD
                     ILLEEVCAWATCVTGRPVLFRYTREEEFIANTSRHVAKVTVKLGAKKDGRLTAVKMDF
                     RANTGPYGNHSLTVPCNGPALSLPLYPCDNVDFQVTTYYSNICPNGAYQGYGAPKGNF
                     AITMALAELAEQLQIDQLEIIERNRVHEGQELKILGAIGEGKAPTSVPSAASCALEEI
                     LRQGREMIQWSSPKPQNGDWHIGRGVAIIMQKSGIPDIDQANCMIKLESDGTFIVHSG
                     GADIGTGLDTVVTKLAAEVLHCPPQDVHVISGDTDHALFDKGAYASSGTCFSGNAARL
                     AAENLREKILFHGAQMLGEPVADVQLATPGVVRGKKGEVSFGDIAHKGETGTGFGSLV
                     GTGSYITPDFAFPYGANFAEVAVNTRTGEIRLDKFYALLDCGTPVNPELALGQIYGAT
                     LRAIGHSMSEEIIYDAEGHPLTRDLRSYGAPKIGDIPRDFRAVLVPSNDKVGPFGAKS
                     ISEIGVNGAAPAIATAIHDACGIWLREWHFTPEKILTALEKI"
     gene            complement(4338..5117)
                     /locus_tag="IRB70_004375"
     CDS             complement(4338..5117)
                     /locus_tag="IRB70_004375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-dependent oxidoreductase
                     FAD-binding subunit"
                     /protein_id="HBC0634214.1"
                     /translation="MIEQFFRPDSVEQALELKRRYQDEAVWFAGGSKLNATPTRTDKK
                     IAISLQDLELDWVDWDNGALRIGAMSRLQTLRDARFIPAALREALGFVYSRHIRNQST
                     IGGEIAARQEESVLLPVLLALDAELVFGNGETLSIEDYLTCPCDRLLTEIIIKDPYRT
                     CATRKISRSQAGLTVVTAAVALTDHDGMRIALDGVASKALRLHDVEKQNLEGDALEQA
                     VANAIFPQEDLRGSVAYKRYITGVLVADLYADCQQAGEEAV"
     gene            complement(5168..6496)
                     /gene="ssnA"
                     /locus_tag="IRB70_004376"
     CDS             complement(5168..6496)
                     /gene="ssnA"
                     /locus_tag="IRB70_004376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative aminohydrolase SsnA"
                     /protein_id="HBC0634215.1"
                     /translation="MLILKNVTAVQLHPAKVQEGVDIAIENDVIVAIGDALTQRYPDA
                     SYKEMHGRIVMPGIVCSHNHFYSGLSRGIMANIAPCPDFISTLKNLWWRLDRALDEES
                     LYYSGLICSLEAIKSGCTSVIDHHASPAYIGGSLSTLRDAFLKVGLRAMTCFETTDRN
                     SGIKELQEGVEENIRFARQIDEAKKAATEPYLVEAHIGAHAPFTVPDAGLEMLREAVK
                     TTGRGLHIHAAEDLYDVSYSHHWYGKDLLARLTQFDLIDSKTLVAHGLYLSKDDITLL
                     NQRDAFLVHNARSNMNNHVGYNHHLSDIRNLALGTDGIGSDMFEEMKFAFFKHRDAGG
                     PLWPDSFAKALANGNELMSRNFGAKFGLLEAGYKADLTICDYNSPTPLLADNIAGHIA
                     FGMGSGSVHSVMVNGVMVYEDRQFNFDCDSIYAQARKAAASMWRRMDALA"
     gene            complement(6499..9597)
                     /gene="ygfK"
                     /locus_tag="IRB70_004377"
     CDS             complement(6499..9597)
                     /gene="ygfK"
                     /locus_tag="IRB70_004377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative selenate reductase subunit YgfK"
                     /protein_id="HBC0634216.1"
                     /translation="MGDIMRPIPFEELLTRIFDEYQQQRSIFGIPEQQFYSPVKGKTV
                     SVFGETCATPVGPAAGPHTQLAQNIVTSWLTGGRFIELKTVQILDRLELEKPCIDAED
                     ECFNTEWSTEFTLLKAWDEYLKAWFALHLLEAMFQPSDSGKSFIFNMSVGYNLEGIKQ
                     PPMQQFIDNMMDASDHPKFAQYRDALNKLLQDEAFLARHGLQEKRESLQALPARIPTS
                     MVQGVTLSTMHGCPPHEIEAICRYMLEEKGLNTFVKLNPTLLGYARVREILDVCGFGY
                     IGLKEESFDHDLKLTQALEMLERLMVLAKEKSLGFGVKLTNTLGTINNKGALPGEEMY
                     MSGRALFPLSINVAAVLSRAFDGKLPISYSGGASQLTIRDIFDTGIRPITMATDLLKP
                     GGYLRLSACMRELEGSDAWGLDHVDVERLNKLAADALTMEYTQKHWKPEERIEVAEDL
                     PLTDCYVAPCVTACAIKQDIPEYIRLLGEHRYADALELIYQRNALPAITGHICDHQCQ
                     YNCTRLDYDSALNIRELKKVALEKGWNEYKQRWHKPAGSGSRHPVAVIGAGPAGLAAG
                     YFLARAGHPVTLFEREANAGGVVKNIIPQFRIPAELIQHDIDFVAAHGVKFEYGCSPD
                     LTVEQLKNQGFHYVLIATGTDKNSGVKLAGDNQNVWKSLPFLREYNKGTALKLGKHVV
                     VVGAGNTAMDCARAALRVPGVEKATVVYRRSLQEMPAWREEYEEALHDGVEFRFLNNP
                     ERFDADGTLTLRVMSLGEPDEKGRRRPVETNETVTLHVDSLITAIGEQQDTEALNAMG
                     VPLDKNGWPDVDHNGETRLTDVFMIGDVQRGPSSIVAAVGTARRATDAILSRENIRSH
                     QNDKYWNNVNPAEIYQRKGDISITLVNSDDRDAFVAQEAARCLECNYVCSKCVDVCPN
                     RANVSIAVPGFQNRFQTLHLDAYCNECGNCAQFCPWNGKPYKDKITVFSLSQDFDNSS
                     NPGFLVEDCRVRVRLNNQSWVLNIDSEGQFNNVPPELNDMCRIISHVHQHHHYLLDRV
                     EV"
BASE COUNT         2399 a         2549 c         2544 g         2388 t
ORIGIN      
        1 cgccagcaca aatagggttt tcaactaata cataaataga ggctggcaat attttaaaaa
       61 tttcgggatc gtaggagacg ccaagcccta aacctaaaga agtggcgaca ataagtgttt
      121 cacgccgctt taatccgttg gtgatgatga tgcgaatccc agcgatggca atcatggaaa
      181 acatcaacgt cattgcgcct cccagaactg ccgagggtat ggttgtgaag aagccgccaa
      241 tcatcggaaa caagccgagg ataaccagca ttaccgcgat ggttcgcccg acataacgtg
      301 aagcgacgcc agtcatctga ataaccccat tattttgcgc aaacgtggtt aatggtaatg
      361 atccgacagc ggaggcgata acagaaacca gaccatctgc cagcacgccg cctttcagtc
      421 gggactgata ctcttccccc tgaatggggc ggcgggaaac cattgccgtg gcggtgatat
      481 cgccgactgc ttccagcacg ctaagcagat aaatcgtgcc aaccaccagg aactgatgga
      541 agctaaaact aaagccgtat ttgaacggat gcgggatggt gattaacggc aaattgcgca
      601 tactgctgaa atccaccatg cccaggcata acgatgcgat atagccgaca catagcccaa
      661 tggcgatccc tcccatgcgt agcaacggac tgcgacagca gttaaagccg atcaccacaa
      721 ttaaaaccaa taaaccaacg ccgagatgtt cgtaattgcc gaacgtaccg ctgcttttgg
      781 ctgcaaatcc tccaccaaaa tcgataatgc cgactttaat caggcttaag ccgatcatca
      841 gtaccacaat accgctgacg gtaggcgtaa taacccgacg taaatagggc aggataaatg
      901 aagatccgac aaccagaaat gcgccaacga aggagacgcc gaggagcgac gacatgatta
      961 actcttcgtg aaaaccgtcg cttttcatgc tgctgcccag cgcaatcatg accgtaacaa
     1021 atgaaaaatt gactgactga attgagagaa gaccagaacc gacgatgccg tagcggttta
     1081 cttgtaacca ggtaccaata ccagaggcga tcatcgccat agaaacaaga taggcagttg
     1141 tttcagcgga aagctgtaag gtcgcaccca cgattaacgc gggggttacc atcggaacga
     1201 aaattgccaa cagatgggta atggcaccta cgagagcctg atgaaaggga gggcgatcct
     1261 ccagttcaaa tataaggtca gaacctgcat ggtttatatc agacatccct tcactccttt
     1321 taaagtaaat ttgatcatct gaattagtaa aataaattcc cacgaatttg gggcgcagga
     1381 cgccttgaga acggcttatc tcattttcgc agtcactatt tagtcatcgt ccaaacagag
     1441 aaacaggccg ccgaagcggc catttattac ttatattttt tccagcgcgg tgagtatttt
     1501 ctccggtgtg aaatgccatt cgcgtaacca gatgccgcag gcatcgtgaa ttgcggtagc
     1561 aatcgccgga gctgcgccat ttacaccgat ttccgagatc gatttcgccc cgaatgggcc
     1621 gactttatcg ttgctcggca ccagcacagc gcggaaatca cgcggaatgt caccaatttt
     1681 cggtgcgccg taactgcgta aatcacgcgt taacgggtga ccttcggcgt cataaatgat
     1741 ttcttcgctc atactgtggc cgattgcacg aagggtggca ccgtagattt gtcccaacgc
     1801 taactctgga ttgaccggtg taccgcaatc cagcaaggcg tagaatttat ccaggcggat
     1861 ttcacccgta cgcgtgttga cggcaacttc agcgaagttc gcgccatacg ggaaggcgaa
     1921 atcaggcgtg atataactgc cagttcccac cagtgaacca aagccggtgc cggtttcgcc
     1981 tttatgggca atatccccga aactaacttc gcctttcttg ccgcgaacga cgcccggcgt
     2041 tgctagttga acatctgcca ctggctcacc caacatttgc gcaccgtgga aaagaatttt
     2101 ctcccgcaga ttttccgctg ccaaacgcgc cgcgttaccc gagaagcaag taccggacga
     2161 ggcatatgcg cctttatcaa acagtgcatg atcggtatca ccagagataa catgcacgtc
     2221 ctgcggtggg cagtgcagca cttctgctgc cagtttcgtc accacagtat ccaaaccagt
     2281 accaatatcc gcaccgccag aatgaacgat aaaggtaccg tctgattcca gtttgatcat
     2341 gcagttagcc tgatcgatat ctgggatccc tgatttctgc atgataatgg cgacgccacg
     2401 accgatgtgc cagtcaccgt tttgtggttt tggtgaagac cattggatca tctcgcgacc
     2461 ctgacgcagg atctcttcca gtgcgcagct ggcggcggaa ggaacggagg tcggcgcttt
     2521 accttcaccg attgcaccga gaattttcag ctcttgccct tcgtgtaccc ggttacgttc
     2581 gataatttcc agttggtcga tctgtaactg ttcagccagt tccgctaatg ccatggtgat
     2641 agcgaagtta cctttcggtg cgccataacc ctgataagca ccatttgggc aaatgttgct
     2701 gtagtaggtg gtgacctgga aatcgacgtt atcgcacgga tataacggca gcgacagcgc
     2761 cggtccgtta cacggtacgg tgagtgagtg gttgccgtaa gggccagtgt tggcgcggaa
     2821 atccatcttc actgccgtca ggcgaccatc ttttttcgcg cccagtttga cggtgacttt
     2881 cgcgacgtga cgagaggtgt tagcaataaa ctcttcttca cgggtgtagc ggaacagtac
     2941 cggacgcccg gtcacgcagg ttgcccaggc gcacacttct tccagcagga tgtcctgttt
     3001 ggaaccaaaa ccgccgccaa ctcgctcttt aatgacatga actttatgtt gtttcatgcc
     3061 cacgaggcgc gcgacctggc ggcgtaagtg ccatggtacc tgggtggagg cgtggataac
     3121 cagacgatcg ccgtccatac gggtaaagca gatatgtgtt tcagtcgggc actgctgcgc
     3181 ctgcgttgag ttataggttc gctcaatgat cacatcggca tcggcaaagc ctttgtccat
     3241 atcgccaata tgaccatgaa tactggcagc gatatttttg cgtgggcgag aaccgatcgg
     3301 gaagttgatg atcatatgct cgccgcgctg ggctgcatgg ctgttatcat cttccagagt
     3361 atctggcgca ccagcaacat acaccaccgg ttcatcgtgc accacaggcg catcttccgc
     3421 cattgcctcg tcaatcgaca ttactggctt aagcacttca tattcaacgt cgatgagctt
     3481 cagtgcttcg agcgcaatgt cttcactttc ggctactacc gcagcaacgc gatcgccgac
     3541 gtgacgcatt ttcttgccga acattcggcg gtcaagcggt gacggttccg gtgcgctctg
     3601 accacccggg gtatagtaaa tatccgggca attcaggtga gtaataacgt gaacgacgcc
     3661 cggtaaggct tcagctttgc tgacatccag atgagtaatc agtgcgtgag cgtgtgggct
     3721 acgtaacatt ttaatgacgc aggcgtcagc cgttacgcgg tcttcaacat agcagggttt
     3781 cgcctgcacc attttcgcgg catcagtttt aggataatgc ttaccaatga cttcaaggtc
     3841 atcgcggaaa gtcggagcga tatcaatggt ggcctgcgga ttatttttac gtgcaaccgc
     3901 cagttcaatg acctgatagt attgttgcca gcctgcatcg cggctgaaca aaccagaaag
     3961 cgcgtcgtcg atctcttcgc gggtaggtgc ggcaatgcga tcgagaagat cggtgataat
     4021 cagagccgca gctggatcgt tataaccaga ctgcaccacg ccaacatcaa ccattgcctg
     4081 ttgaaccaga cttaactcgt tccatttgcc cagagactct gcggtacgaa tatctgcctt
     4141 ctctaactgt gcggcgataa gcaaggacgc gttaacgata ttaccgttaa agattattgc
     4201 gtcagaaccg gcaaacccga agccatcatc actgttgcgt acagagtgca ttcccatgtt
     4261 aaacaacagc ttttgcacgt tttcaccagg attaacggtc agctcctgag gcgcgccatt
     4321 taaagtaaag tggatgatca tacggcttcc tccccagcct gttggcagtc ggcatacagg
     4381 tcggctacca gaactcccgt gatatagcgt ttataggcca cgctgccccg caaatcttcc
     4441 tgcgggaaaa tggcgttggc gacagcctgt tcaagggcat cgccttccag gttttgtttt
     4501 tcgacatcgt gcagacgcag tgctttactg gccacgccat ccaacgcaat tcgcataccg
     4561 tcgtgatcgg ttaacgcaac ggctgccgtt actaccgtta acccagcctg agaacggcta
     4621 attttgcggg tcgcacaggt gcgatacgga tctttaatga taatttcggt tagcaggcga
     4681 tcgcatgggc aggtcaggta gtcctcgatt gacagcgttt cgccgttgcc aaaaaccagt
     4741 tcagcatcca gtgccagcag gacgggaagc agcaccgact cttcctgccg ggcggcgatt
     4801 tcaccaccaa tggtcgactg attacgaata tggcgagagt agacaaagcc gagagcctca
     4861 cgcagtgctg caggaataaa ccgtgcatca cgcagtgttt gcaagcgaga catcgcgcca
     4921 atccgcaatg caccgttatc ccagtcaacc cagtccagtt ccagatcctg taaggatatg
     4981 gcaatctttt tatcggtacg ggttggtgtg gcgttgagtt tactgccccc ggcgaaccag
     5041 acggcttcat cctggtagcg gcgcttcagt tccagcgctt gttcgacaga gtcgggtctg
     5101 aaaaattgtt caatcatcgt ctttccttaa tttcccctct tctctgaaag aagaggggag
     5161 ctgttattta tgccagcgca tccatccgac gccacatact ggcagcggct tttctggctt
     5221 gcgcataaat ggaatcgcaa tcgaagttaa actgacggtc ttcatagacc atcacaccat
     5281 tgaccatcac gctgtgaacg ctgcctgagc ccataccgaa agcgatatgc ccggcgatat
     5341 tgtctgccag cagcggcgtc ggcgagttgt aatcgcaaat ggttaaatcg gctttgtaac
     5401 cggcttccag aagcccaaat ttcgcgccaa agttgcggct catcagttcg ttgccgttag
     5461 ccagtgcttt ggcaaaactg tcaggccaca gcgggccacc cgcatcgcga tgtttaaaga
     5521 aggcaaattt catctcttca aacatgtccg aaccaatgcc gtccgttccc aacgccagat
     5581 tgcggatgtc gctaaggtga tggttgtagc cgacatggtt gttcatgttt gaacgggcgt
     5641 tatgcaccag gaacgcatcg cgctgattga gtagggtgat gtcatctttc gacaagtaca
     5701 gcccatgagc gaccagcgtt ttgctgtcga tgagatcgaa ttgcgtcagt cgtgccagta
     5761 ggtctttgcc gtaccagtgg tgactgtagg aaacgtcgta aaggtcttcc gcagcgtgaa
     5821 tatgcaaacc acgacctgtg gttttcacgg cttcacgcag catctccaga ccggcatccg
     5881 gcacggtaaa cggcgcgtga gcgccgatat gtgcttccac cagatacggc tcggttgctg
     5941 ctttcttcgc ctcatcaatc tgacgggcga agcggatgtt ttcttctaca ccttcctgca
     6001 actctttgat gccgctgtta cggtcagtag tttcaaaaca ggtcatcgcg cgcaggccaa
     6061 cttttaaaaa tgcgtcgcgc aatgtggaga gtgacccgcc gatataggct ggagaggcat
     6121 ggtgatcgat aaccgatgta catccgctct taatcgcttc cagggaacaa atcagtccgc
     6181 tgtaatagag cgactcttca tcaagggcgc gatcgagccg ccaccagaga tttttcagcg
     6241 ttgagatgaa atccgggcag ggggcgatat ttgccataat tccgcgggaa agtcccgagt
     6301 aaaaatggtt atgcgagcag acaattcccg gcatcacaat ccgaccatgc atctctttgt
     6361 agctggcatc ggggtagcgt tgcgtcaggg catcgccgat agcgacaatc acatcatttt
     6421 cgatggcgat atcaacgcct tcctgcactt tcgccgggtg taactgcact gcggtgacat
     6481 tcttcagaat caacatgatt acacctccac gcggtccagc agataatgat gatgctggtg
     6541 gacatggcta ataatgcggc acatatcgtt cagctccggt ggtacgttgt tgaactgacc
     6601 ttcgctgtcg atgtttaaca cccagctttg gttattcaga cgtactcgta cccggcaatc
     6661 ttccacaagg aagcctgggt tgctgctgtt atcaaagtct tgcgacaggc tgaagacggt
     6721 gattttgtct ttgtacggtt taccgttcca cgggcagaat tgggcgcagt tgccgcattc
     6781 gttgcagtag gcatcgagat gcagcgtctg gaaacggttc tggaagccag gaaccgcaat
     6841 ggagacgttg gcgcggttcg ggcagacatc cacacacttg ctgcaaacgt agttacattc
     6901 aaggcagcgt gcggcttcct gggcgacaaa cgcgtcacga tcgtcactgt tcaccagagt
     6961 gatagagata tcgcctttac gttgatagat ttccgccgga ttgacgttgt tccagtattt
     7021 atcgttctgg tgggaacgga tattttccct actcaggatt gcatcggtcg cccgacgcgc
     7081 ggttccgaca gcagcgacaa tggaggatgg tccgcgctgt acgtcgccga tcataaagac
     7141 gtcagtcaga cgcgtttcgc cattatggtc gacgtctggc cagccgtttt tgtccagcgg
     7201 cacgcccatt gcattcaggg cttcagtatc ctgctgttca ccaatggcgg tgatcaggct
     7261 gtctacatgc agcgttactg tttcgttggt ttcaaccgga cggcgacgac ctttctcatc
     7321 aggttcgcca agcgacataa cgcgcaaggt taaggtgcca tcagcatcga aacgttccgg
     7381 attattcaga aaacggaact ccacgccgtc gtgcaacgct tcttcatact cttcgcgcca
     7441 tgctggcatc tcttgcagtg aacgacggta aacgaccgtt gctttttcta cgcctggaac
     7501 gcgtaacgcc gcacgagcgc agtccattgc ggtgttaccc gccccgacaa cgaccacatg
     7561 tttgcccagc ttgagcgctg tgcccttgtt gtattcacgc aggaagggga gtgatttcca
     7621 gacattttgg ttgtcgcccg ccagtttcac accgctattt ttatcagtgc cggtggcaat
     7681 cagaacatag tggaagccct gattttttaa ctgttcaacg gtcagatcgg gtgagcagcc
     7741 atactcaaat ttcacgccgt gagcggcaac aaaatcgata tcgtgctgaa ttaactctgc
     7801 aggaatacgg aactgaggaa tgatattttt caccacgccg cccgcattgg cttcgcgttc
     7861 aaacagcgta accggatggc ccgctctggc aaggaagtaa cctgctgcca gacccgccgg
     7921 acctgcacca atcacggcaa ccggatggcg tgaaccagaa ccggctggtt tgtgccagcg
     7981 ttgcttatat tcattccaac ctttttccag cgcgactttt ttcagttcgc ggatattcag
     8041 cgcactgtcg taatccaggc gggtacagtt gtattggcac tggtgatcgc aaatatgacc
     8101 ggtaatggcg ggcagggcgt tgcgttggta gatgagttcc agtgcgtcgg catagcggtg
     8161 ttcgccaagc agacggatgt attccggaat atcctgttta atggcgcaag cagtaacgca
     8221 cggtgcaacg tagcagtcgg tcagcggcag gtcttctgcc acttcaatac gctcttctgg
     8281 cttccagtgt ttctgagtgt attccatggt taacgcgtct gctgccagtt tgttcagtcg
     8341 ttcgacgtca acatggtcaa gcccccaggc gtcggagcct tccagctcgc gcatgcaggc
     8401 acttaagcgc agatagccgc caggtttcag caggtcggtt gccatagtaa tagggcgaat
     8461 accagtatca aaaatatcgc ggatagtcag ctgactggca ccaccggaat aagaaatggg
     8521 cagtttgccg tcaaaggcgc gagagagaac tgctgcaaca ttgatggaga gcgggaacag
     8581 cgcacggcct gacatataca tctcttcacc aggcagtgcg cctttattgt tgatggtgcc
     8641 gagagtgtta gtcagtttta cgccaaagcc gagtgatttt tcttttgcca gtaccatcag
     8701 gcgttccagc atttccagcg cttgcgtcag cttgaggtcg tgatcaaatg actcttcttt
     8761 taagcctatg taaccgaaac cgcagacatc gaggatctca cgaacacgcg cataccccag
     8821 taaggtcggg ttaagtttca caaaggtgtt gagtcctttt tcttccagca tgtagcgaca
     8881 aatggcttcg atttcatgcg gaggacagcc gtgcatggtg gagagggtaa caccttgtac
     8941 catgctggtg gggatgcgag cgggtaaggc ttgcaagctt tcgcgttttt cctgcaatcc
     9001 gtggcgggct aaaaatgcct catcctggag tagcttatta agtgcatcgc gatattgagc
     9061 gaatttcgga tggtcagatg cgtccatcat attgtcgatg aactgttgca tcggcggttg
     9121 cttaatacct tcgaggttgt aaccgacgct catattaaag atgaacgatt taccggaatc
     9181 agaaggctgg aacatcgctt cgagaaggtg cagggcaaac caggctttga ggtattcatc
     9241 ccaggcttta agcagggtaa attcggtaga ccattcggtg ttaaagcact cgtcttcggc
     9301 atcgatacag ggcttttcca gctccaggcg gtcaagaatt tggacggttt ttagttcgat
     9361 gaagcgtccg ccagtcagcc aggaagtgac aatattttgc gcgagctgcg tgtgcggacc
     9421 agcggcaggg ccgacgggag tggcacaggt ttcaccgaag acgctaacag ttttaccttt
     9481 tacgggtgag taaaactgtt gctcgggaat accaaagatt gagcgttgtt gttggtattc
     9541 atcaaatatg cgcgtcaaaa gttcctcaaa cggaatggga cgcataatat cccccataac
     9601 cctctcctta gcttatacag atatcattga gtgaccggtg ttgagaaatc cggtggttta
     9661 gggggataga gcaacaatcg caccactctt gccaggtttg gcgggaaata taaaaaaatg
     9721 tgaggcggct cgaaacttaa tggctttttg tgaatgaact cacaggtgcc aaatgagaat
     9781 taaaatcact cctgaaaatt attattgcca gcccatttat cactttttct cttttctcaa
     9841 aatcagtgat tccttatcat tatgataaag agtacaggag
//
LOCUS       DADXDL010000132         9816 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.132, whole genome shotgun sequence.
ACCESSION   DADXDL010000132 DADXDL010000000
VERSION     DADXDL010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9816)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9816)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9816
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.132"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            200..1513
                     /gene="gltP"
                     /locus_tag="IRB70_004378"
     CDS             200..1513
                     /gene="gltP"
                     /locus_tag="IRB70_004378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate/aspartate:proton symporter GltP"
                     /protein_id="HBC0634217.1"
                     /translation="MKNIKFSLAWQILFAMVLGILLGSYLHYHSDSRDWLVVNLLSPA
                     GDIFIHLIKMIVVPIVISTLVVGIAGVGDAKQLGRIGAKTIIYFEVITTVAIILGITL
                     ANVFQPGAGVDMSQLATVDISKYQSTTEAVQSSSHGIMGTILSLVPTNIVASMAKGEM
                     LPIIFFSVLFGLGLSSLPATHREPLVTVFRSISETMFKVTHMVMRYAPVGVFALIAVT
                     VANFGFSSLWPLAKLVLLVHFAILFFALVVLGIVARLCGLSVWILIRILKDELILAYS
                     TASSESVLPRIIEKMEAYGAPASITSFVVPTGYSFNLDGSTLYQSIAAIFIAQLYGID
                     LSIWQEIILVLTLMVTSKGIAGVPGVSFVVLLATLGSVGIPLEGLAFIAGVDRILDMA
                     RTALNVVGNALAVLVIAKWEHKFDRKKALAYEREVLGKFDKTADQ"
     gene            complement(1705..2394)
                     /locus_tag="IRB70_004379"
     CDS             complement(1705..2394)
                     /locus_tag="IRB70_004379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sel1 repeat family protein"
                     /protein_id="HBC0634218.1"
                     /translation="MKKIIALMLFLTFFAHANDSEPGSQYLKAAEAGDRRAQYFLADS
                     WFSSGDLSKAEYWAQKAADSGDADACALLAQIKITNPVSLDYPQAKVLAEKAAQAGSK
                     EGEVTLAHILVNTQAGKPDYPKAISLLENASEDLENDSAVDAQMLLGLIYANGVGIKA
                     DDNKATWYFKRSSAISRTGYSEYWAGMMFLNGEEGFIEKNKQKALHWLNLSCMEGFDT
                     GCEEFEKLTNG"
     gene            complement(2488..4635)
                     /gene="fdhF"
                     /locus_tag="IRB70_004380"
     CDS             complement(2488..4635)
                     /gene="fdhF"
                     /locus_tag="IRB70_004380"
                     /EC_number="1.17.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_except=(pos:complement(4216..4218),aa:Sec)
                     /transl_table=11
                     /product="formate dehydrogenase subunit alpha"
                     /protein_id="HBC0634219.1"
                     /translation="MKKVVTVCPYCASGCKINLVVDNGKIVRAEAAQGKTNQGTLCLK
                     GYYGWDFINDTQILTPRLKTPMIRRQRGGKLEPVSWDEALNYVAERLSAIKEKYGPDA
                     IQTTGSSRGTGNETNYVMQKFARAVIGTNNVDCCARVUHGPSVAGLHQSVGNGAMSNA
                     INEIDNTDLVFVFGYNPADSHPIVANHVINAKRNGAKIIVCDPRKIETARIADMHIAL
                     KNGSNIALLNAMGHVIIEENLYDKAFVASRTEGFEEYRKIVEGYTPESVEDITGVSAS
                     EIRQAARMYAQAKSAAILWGMGVTQFYQGVETVRSLTSLAMLTGNLGKPHAGVNPVRG
                     QNNVQGACDMGALPDTYPGYQYVKDPANREKFAKAWGVESLPAHTGYRISELPHRAAH
                     GEVRAAYIMGEDPLQTDAELSAVRKAFEDLELVIVQDIFMTKTASAADVILPSTSWGE
                     HEGVFTAADRGFQRFFKAVEPKWDLKTDWQIISEIATRMGYPMHYNNTQEIWDELRHL
                     CPDFYGATYEKMGELGFIQWPCRDTSDADQGTSYLFKEKFDTPNGLAQFFTCDWVAPI
                     DKLTDEYPMVLSTVREVGHYSCRSMTGNCAALAALADEPGYAQINTEDAKRLGIEDEA
                     LVWVHSRKGKIITRAQVSDRPNKGAIYMTYQWWIGACNELVTENLSPITKTPEYKYCA
                     VRVEPIADQRAAEQYVIDEYNKLKTRLREAALA"
     gene            complement(4833..6299)
                     /gene="mdtP"
                     /locus_tag="IRB70_004381"
     CDS             complement(4833..6299)
                     /gene="mdtP"
                     /locus_tag="IRB70_004381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter outer membrane
                     subunit MdtP"
                     /protein_id="HBC0634220.1"
                     /translation="MINRQLSRLLLCSILGSTTLISGCALVRKDSAPHQQLKPEQIKL
                     ADDIHLASSVWPQAQWWKQLNDPQLDALIQRTLSGSHTLAEAKLREEKAQSQADLLDA
                     GSQLQVAALGMLNRQRVSANGFLSPYAMDAPALGMDGPYYTEATVGLFAGLDLDLWGV
                     HRSAVAAAIGAHNAALAETAAVELSLTTGVAQLYYSMQASYQMLDLLEQTRNVIDYAV
                     KAHQSKVAHGLEAQVPFHGARAQILAVDKQIAAVKGQITETRESLRALIGAGASDMPE
                     IKPVALPRVQTGIPATLSYELLARRPDLQAMRWYVQASLDQVDSARALFYPSFDIKAF
                     FGLDSIHLDTLFKKTSRQFNFIPGLKLPLFDGGRLNANLEGTRAASNMMIERYNQSVL
                     NAVRDVAVNGTRLQTLNDEREMQAERVEATRFTQRAAEAAYQRGLTSRLQATEARLPV
                     LAEEMSLLMLDSRRVIQSIQLMKSLGGGYQAAPVVEKK"
     gene            complement(6296..8347)
                     /gene="mdtO"
                     /locus_tag="IRB70_004382"
     CDS             complement(6296..8347)
                     /gene="mdtO"
                     /locus_tag="IRB70_004382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313090.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter permease subunit
                     MdtO"
                     /protein_id="HBC0634221.1"
                     /translation="MSALNSLPLPVVRLLAFFHEELSERRPGRVPQTVQLWVGCLLVI
                     LISMTFEIPFVALSLAVLFYGIQSNAFYTKFVAILFVVATVLEIGSLFLIYKWSYGEP
                     LIRLIIAGPILMGCMFLMRTHRLGLVFFAVAIVAIYGQTFPAMLDYPEVVVRLTLWCI
                     VVGLYPTLLMTLIGVLWFPSRAITQMHQALNDRLDDAISHLTNSLTPLPETRIEREAL
                     ALQKLNVFCLADDADWRTQSAWWQSCVATVTYIYSTLNRYDPTSFADSQAIIEFRQKL
                     ASEINKLQHAIAEGQCWQSDWRITESEAMAARECNLENICQTLLQLGQMDPNTPPTPA
                     TKPPSMVADAFTNPDYMRYAVKTLLACLICYTFYSGVDWEGIHTCMLTCVIVANPNVG
                     SSYQKMVLRFGGAFCGAILALLFTLLVMPWLDNIVELLFVLAPIFLLGAWIATSSERS
                     SYIGTQMVVTFALATLENVFGPVYDLVEIRDRALGIIIGTVVSAVIYTFVWPESEART
                     LPQKLAGALGMLSKVMRIPRQQEVTALRTYLQIRIGLHAAFNACEEMCQRVALERQLD
                     SEERALLIERSQTVIRQGRDILHAWDATWNSAQALDNALQPDRAGQFADALEKYAAGL
                     ATALSRSPQITLEETPASQAILPTLLKQEQHVCQLFARLPDWTAPALTPATEQAQGAT
                     Q"
     gene            complement(8347..9378)
                     /gene="mdtN"
                     /locus_tag="IRB70_004383"
     CDS             complement(8347..9378)
                     /gene="mdtN"
                     /locus_tag="IRB70_004383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter periplasmic adaptor
                     subunit MdtN"
                     /protein_id="HBC0634222.1"
                     /translation="MESTPKKAPRSKFPALLVVALALVALVFVIWRVDSAPSTNDAYA
                     SADTIDVVPEVSGRIVELAVTDNQAVKQGDLLFRIDPRPYEANLAKAEASLAALDKQI
                     MLTQRSVDAQQFGADSVNATVEKARAAAKQATDTLRRTEPLLKEGFVSAEDVDRARTA
                     QRAAEADLNAVLLQAQSAASAVSGVDALVAQRAAVEADIALTKLHLEMATVRAPFDGR
                     VISLKTSVGQFASAMHPIFTLIDTRHWYVIANFRETDLKNIRSGTPATIRLMSDSGKT
                     FEGKVDSIGYGVLPDDGGLVLGGLPKVSRSINWVRVAQRFPVKIMVEKPDPEMFRIGA
                     SAVANLEPQ"
     gene            complement(9397..9672)
                     /locus_tag="IRB70_004384"
     CDS             complement(9397..9672)
                     /locus_tag="IRB70_004384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_001165334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634223.1"
                     /translation="MPTVLSRMAMQLKKTAWIIPVFMVSGCSLSPAIPVIGAYYPSWF
                     FCAIASLILTLITRRIIQRANINLAFVGIIYTALFALYAMLFWLAFF"
BASE COUNT         2217 a         2619 c         2616 g         2364 t
ORIGIN      
        1 ccataaactc gcgttattat gcattaatgc agcgaaaagc tctgttgtta aagggttgcg
       61 caacataccg cgcaaatgat actgatcata agcgttaaaa aaatctacaa accaacgcaa
      121 cacaattcat gccctggcag tatgtcacgt tctcgcgttt ctgaacgggg aacggcgctc
      181 cattgaggaa gttattctga tgaaaaatat aaaattcagc ctggcctggc agattctgtt
      241 tgctatggtg ctgggcattc tcctgggaag ctacctgcac taccatagcg acagccgcga
      301 ctggctggtc gtcaatttgc tctctccggc gggtgatatc ttcatccatc tgatcaaaat
      361 gattgttgtg ccgattgtga tctccacgct ggtggtgggt atcgcgggtg ttggtgatgc
      421 caaacagctc gggcgtattg gcgcgaaaac cattatttac ttcgaggtga tcaccaccgt
      481 cgccatcatt ttggggatta ctctggcgaa cgtcttccag cccggtgccg gggtggatat
      541 gtcgcagctg gcgaccgtcg atatctcgaa atatcagagc actacggaag cggtacaaag
      601 cagttcccac ggcattatgg gcacgatttt gtcgctggtg ccgacgaaca ttgtggcgtc
      661 gatggcgaaa ggcgaaatgc tgccgatcat cttcttctcg gtgctgtttg gtctggggct
      721 ttcctccctg cccgcgacgc atcgtgaacc gctggtgacc gtgttccgct ccatctctga
      781 aaccatgttt aaagtgactc atatggtgat gcgttatgcg ccggtgggtg tgtttgcgct
      841 gattgcggtg acggtggcta actttggttt ctcgtctctg tggccactgg cgaaactggt
      901 gctgctggtg catttcgcca ttctgttctt cgcgctggtc gtactgggaa ttgtggcgcg
      961 cctgtgcggg ttaagcgtct ggatcctgat tcgtattctg aaagatgagc tgattctggc
     1021 gtactccact gccagctctg aaagcgtact gccgcgaatt attgagaaga tggaagccta
     1081 cggagcaccg gcgtcgatca ccagtttcgt ggtgccgacc ggttactctt ttaaccttga
     1141 tggttcgacg ctgtatcaaa gtattgccgc tattttcatc gctcagctgt atggcattga
     1201 cctgtccatc tggcaggaaa tcattctggt gctgacgctg atggtgacct cgaaagggat
     1261 tgctggcgtg ccgggcgtgt cgtttgtggt gttgctggca acgctgggca gcgtagggat
     1321 cccgctggaa ggtctggcgt ttattgccgg tgttgaccgt atcctcgaca tggcgcgtac
     1381 tgcgctgaac gtggtgggta atgcgctggc ggtgctggtg attgccaagt gggaacacaa
     1441 atttgaccgt aagaaagcgc tggcttatga gcgcgaagtg ctgggcaaat ttgataaaac
     1501 tgcggatcaa taattgaaga ttgccgggga tatccacccg gcaatgtgtg gatgcctgat
     1561 gcgacgcttg ccgcgtctta tcaggcctac gtcagacagc gcaatagcct gatttagcgt
     1621 gattttgtag gtcggataag gcgtttacgc cgcatccgac atcaacgcct gatgcgacga
     1681 ttaacgcgtc ttatcaggcc taccttaacc gttagttaat ttttcaaact cttcacaccc
     1741 ggtatcaaac ccttccatac agctcagatt caaccagtgc agcgccttct gtttgttctt
     1801 ctcgataaaa ccttcttcac cgtttaagaa catcattccc gcccagtact cggaataacc
     1861 ggttcgggaa atcgcggagc tacgtttgaa ataccaggtt gctttgttat cgtcggcctt
     1921 aatgcccacg ccgttggcgt aaatcaaacc aagcagcatt tgggcatcga cggcagagtc
     1981 gttctccaga tcttccgagg cgttttctaa cagcgaaatc gcctttggat aatccggttt
     2041 acccgcttgc gtatttacca gaatatgcgc cagcgttact tcaccttctt tactgcccgc
     2101 ttgcgccgct ttctctgcaa gaacttttgc ttgtggatag tccagactga ccggattggt
     2161 gattttgatc tgcgctaaca gcgcgcaggc atcagcatca ccgctgtcgg cggctttctg
     2221 tgcccaatat tcggctttgc tcaaatcgcc ggagctaaac cagctgtcgg caagaaaata
     2281 ttgtgcgcgt cggtccccgg cctctgctgc ctttaaatac tggctgccag gctcggagtc
     2341 gttcgcgtgg gcaaagaatg tcaaaaacaa catcaatgcg ataatttttt tcattttgat
     2401 aatacgattg ggtagggagt aaccagtata aagagttcga atggataaaa aaacagcctc
     2461 cgaaaggagg ctgtagaaag gactgtatta cgccagtgcc gcttcgcgca ggcgagtttt
     2521 caacttgttg tactcgtcaa tcacatactg ctcggcggcg cgctgatcgg cgatcggctc
     2581 gacgcgcacg gcgcagtatt tgtattccgg cgttttcgta atcgggctta agttttcggt
     2641 aaccagctcg ttacaggcac caatccacca ctggtaggtc atgtaaatcg cccctttgtt
     2701 cggacgatcg ctgacctgcg cacgggtgat aattttgcct ttacgcgagt gcacccaaac
     2761 caatgcctca tcttcaatac ccagacgttt ggcgtcttcg gtattgattt gtgcgtagcc
     2821 aggttcatca gccagcgccg ccagtgccgc acagttaccg gtcatcgaac ggcaagagta
     2881 gtgaccgact tcacgcaccg ttgacagtac catcgggtac tcgtcggtga gtttgtcgat
     2941 tggcgctacc cagtcgcagg tgaagaactg cgccagaccg ttcggagtat caaacttctc
     3001 tttaaacaga taagaagtcc cctgatcggc atctgaagta tcgcgacaag gccactgaat
     3061 gaagcccagt tcgcccattt tctcgtaagt cgcaccgtag aaatccgggc acagatgacg
     3121 caactcatcc cagatctcct gggtgttgtt gtagtgcatc ggataaccca tacgggtggc
     3181 gatttcactg atgatttgcc agtccgtttt caaatcccat ttcggttcaa ctgctttaaa
     3241 gaaacgctgg aagccacggt cagccgcagt aaacacgcct tcatgctcgc cccatgacgt
     3301 tgacggtaaa atgacatccg ccgccgacgc ggttttggtc ataaagatgt cctgaacgat
     3361 gaccagttcc agatcttcaa aggctttacg tactgccgac agctccgcgt cagtttgtag
     3421 cggatcttcg cccataatgt acgcggcacg cacttcacca tgcgctgcgc ggtgcggcag
     3481 ctcgctgatg cgataaccgg tatgagcagg caggctttcc acgccccagg ctttggcgaa
     3541 tttctcgcgg ttagccggat ctttcacgta ctggtatccc ggatacgtat ccggcagcgc
     3601 gcccatatcg caggcaccct gtacgttgtt ctgaccacga accgggttta cacccgcatg
     3661 tggcttaccg aggttaccgg tcagcatcgc gaggctggtc agagaacgca cggtttccac
     3721 gccctggtag aactgggtta cacccatgcc ccacaggatg gcggcgcttt tcgcctgggc
     3781 atacatccgt gccgcctgac gaatctcact ggcgctgacg ccggtgatat cttcaaccga
     3841 ctccggcgtg tagccttcaa cgattttacg atactcttca aagccttctg tacgggaagc
     3901 gacgaacgct ttgtcgtaca gattttcttc aataatgaca tggcccatcg cattcaacag
     3961 cgcgatgttc gagccgtttt tcaatgcaat gtgcatgtca gcaatgcgcg cagtttcaat
     4021 tttgcgcgga tcgcagacga taattttcgc cccgttacgt ttagcgttaa ttacgtgatt
     4081 cgccacgatt gggtgggaat ccgccgggtt gtacccgaaa acgaacacta aatcggtatt
     4141 atcaatttcg ttaatagcat tgctcattgc gccattaccg accgattggt gcagacctgc
     4201 aaccgatggg ccgtgtcaga cacgagcgca gcagtcaacg ttattggtac caataacggc
     4261 gcgcgcaaat ttttgcatta catagttggt ttcgttaccc gtaccacgcg aggagccggt
     4321 cgtctggatg gcatccggac cgtacttctc tttgatggcg ctcaggcgct cggcaacgta
     4381 attcagtgcc tcatcccagg aaacaggttc gagtttgccg ccacgctggc gacggatcat
     4441 gggggttttc aggcgcgggg tcaggatctg ggtatcgtta atgaagtccc agccataata
     4501 acccttcaga cacagggtac cctggttggt tttcccctgc gctgcctccg cccggacgat
     4561 tttgccgtta tcgacgacca ggttgatttt gcaacctgac gcgcaatagg ggcaaaccgt
     4621 gacgactttt ttcatcggtc tcgctccagt taatcaaatc acgcatacgc gctctcgact
     4681 acagtatgca tcttttatgc cacattttat ttggggtcat tccctgatat tacgggcact
     4741 atttattcaa aactctgacg aaaaacaggc tgtcgtcagt tttgacgtga cgaaacgaaa
     4801 taccgcgtga cagccatcac gcggtagaca ttttattttt tctcgacgac gggagccgcc
     4861 tgatacccgc cgcccagcga tttcatcaac tgaatgcttt ggatcacccg gcggctgtcc
     4921 agcatcagta atgacatctc ctcggcaagc actggcaacc gggcttcggt ggcctgtaag
     4981 cggctggtta agccgcgttg ataggcggcc tcggcagcgc gctgggtgaa gcgcgttgct
     5041 tccacgcgtt cagcctgcat ctctcgctcg tcgttaagcg tttgcagacg cgtgccgttg
     5101 acagcaacgt cgcgcaccgc gttcagtact gactggttgt aacgttcaat catcatgttg
     5161 ctggcggcgc gcgtgccttc gagattggca ttcaaccgtc caccgtcaaa cagcggcaat
     5221 ttcagacctg ggataaagtt gaactggcga ctggtttttt tgaataaggt atccaggtgg
     5281 atagaatcca ggccgaaaaa cgctttgata tcaaagctcg gatagaacag cgcccgcgcg
     5341 gaatccacct gatctaatga cgcctgaaca taccagcgca tggcttgcag atccgggcgt
     5401 ctggcgagca actcataaga gagcgttgcc ggaatgccgg tctggactcg cggtaatgcc
     5461 accggtttga tctccggcat atcgctggcg cccgcgccaa tcaatgcgcg cagagattcc
     5521 cgcgtttcag tgatttgccc tttaacggca gcaatttgtt tatcgaccgc cagaatctgt
     5581 gcccgcgcgc cgtggaaagg cacttgcgct tccagaccgt gcgccacttt actctggtgc
     5641 gcttttaccg cgtaatcaat cacattgcgt gtttgttcta acagatcgag catctgatag
     5701 ctggcctgca tactgtaata aagctgcgct acgcccgtgg tcagcgatag ctctactgct
     5761 gcggtttctg ccagcgcggc attatgcgcg ccaatggcgg cggcaaccgc tgagcgatgc
     5821 acaccccaca aatcgagatc cagtccggca aacaaaccta ctgtggcttc cgtatagtac
     5881 ggcccgtcca tccccagtgc gggcgcatcc atcgcataag ggcttaaaaa gccgttcgcc
     5941 gagacgcgtt ggcggttaag catccctaac gctgccacct gcaactgtga accggcatct
     6001 aacaaatcgg cctgcgattg cgctttttct tcccgcagtt tcgcttcggc gagggtgtgt
     6061 gaaccactta gcgtccgttg gatcaaagca tccaactgcg ggtcattgag ttgtttccac
     6121 cactgcgcct gcggccagac ggagctggca agatgaatat catcggccag tttgatttgt
     6181 tccggtttga gctgttgatg aggcgcagaa tccttacgta ccagggcaca gccggaaatc
     6241 agcgtcgtgc tgccgagaat gctgcacaac agcaggcgtg aaagttgacg attgatcatt
     6301 gcgtggctcc ttgtgcctgt tccgtggcgg gcgttaatgc cggggctgtc cagtctggca
     6361 agcgggcgaa aagctggcag acgtgttgct cctgttttaa taaggtcggc aggatggcct
     6421 gcgaggcggg tgtttcttca agcgttattt gaggagaacg actgagtgcg gttgccagac
     6481 cggcggcgta tttctccagg gcgtcggcaa actgaccagc tctgtccggc tgtagtgcgt
     6541 tatccagcgc ctgcgccgag ttccaggtgg catcccaggc gtgaagaata tcgcgaccct
     6601 gacgaataac cgtttgcgaa cgttcaatca gtaaggcgcg ttcttcgctg tccagttgac
     6661 gctccagcgc cacgcgttgg cacatctctt cacaggcatt aaacgccgca tgcagaccta
     6721 tgcgaatttg cagataagtg cgcagagccg tgacttcctg ctgccgtggg atccgcatta
     6781 ctttacttaa catacccagc gcgccagcca gtttttgcgg cagggtgcgc gcttcacttt
     6841 caggccagac aaaggtgtaa atcaccgcgg acaccacggt accaatgatg atacccaggg
     6901 cgcgatcgcg aatttccacc aggtcgtaca ccgggccaaa aacattttcg agcgtggcga
     6961 gcgcgaaggt gaccaccatc tgtgtgccga tataagaaga gcgttcagag ctggtggcaa
     7021 tccatgcgcc caacaggaaa atcggtgcca gcacaaacag caattcgaca atattgtcca
     7081 gccagggcat gaccaataac gtgaataaca gcgccagaat cgcgccgcaa aaggccccgc
     7141 caaaacgcag caccatcttc tggtacgacg aaccgacatt gggattagcg acgatcacgc
     7201 aggtcagcat acaggtgtga atgccttccc agtccacgcc gctgtagaag gtgtaacaga
     7261 tcaaacaggc gagcagcgtt tttaccgcgt agcgcatata gtctggattg gtaaaagcgt
     7321 cggcgaccat tgatggcggt ttggtggcgg gcgttggcgg cgtattcggg tccatctgac
     7381 ccagttgcaa caatgtctgg cagatattct ccaggttaca ttcccgtgcc gccatcgctt
     7441 cactttcagt gatccgccag tcgctttgcc agcactgacc ttcggcaatg gcatgctgca
     7501 gcttgttgat ttctgaggct aatttttgcc ggaattcaat gattgcctgc gaatctgcaa
     7561 aagaggtggg atcgtagcga ttcagcgtcg agtaaatgta ggttaccgtt gccacgcagc
     7621 tttgccacca tgcgctctga gtacgccagt cggcatcgtc cgcgaggcaa aagacattga
     7681 gtttttgcag cgccagcgcc tctctttcaa tccgcgtttc gggtagcggt gtgaggctgt
     7741 tcgtcaggtg gctaatggca tcatcaagcc gatcattaag cgcctgatgc atctgcgtga
     7801 tagcgcggct gggaaaccac agcacgccga ttaacgtcat caataacgtc ggatagaggc
     7861 caacaacgat acaccacagc gttaagcgca cgaccacttc cggatagtcg agcatggcgg
     7921 ggaaggtttg cccgtaaatg gcgacaatgg cgacagcgaa aaagaccagt cccagccgat
     7981 gggtgcgcat caaaaacata catcccatca ggatcggccc tgcgatgatc aatcggatca
     8041 acggttcgcc gtatgaccat ttgtagatca aaaacaggct gccgatctcc agcaccgtgg
     8101 caaccacaaa caagatcgcg acaaatttgg tgtaaaacgc gttggactga ataccgtaaa
     8161 acagcaccgc cagcgatagc gccacaaaag ggatctcaaa agtcatcgag atcagaatca
     8221 ccagcaggca gcctacccag agttgcacgg tctgcggcac acgacctggc cgccgctcgc
     8281 ttaactcttc atgaaagaac gccagcagcc tgaccaccgg taatggcagg gagttgagcg
     8341 cgctcattat tgtggctcaa gattagcgac tgccgaagcg ccgatgcgga acatttccgg
     8401 gtcaggtttt tcaaccatga ttttgaccgg aaaacgctgg gcaacgcgga cccagttaat
     8461 agaacgagac actttcggca ggccgcccag caccaggccg ccgtcatccg gtagcacgcc
     8521 gtagccaatc gaatccactt taccctcgaa ggttttgccg ctgtcgctca tcaggcgaat
     8581 cgttgcgggt gtacctgagc gaatattttt cagatcggtt tcgcggaagt tggcgatcac
     8641 gtaccagtga cgagtgtcga ttagggtaaa aatagggtgc atggcagaag caaattgccc
     8701 gacggaggtt ttgagggaaa tgacccggcc atcaaacggc gcgcgaacgg tcgccatttc
     8761 cagatgcagt ttggtcaggg caatatccgc ttcgaccgcc gcacgttggg cgaccagcgc
     8821 atcgacgccg ctgacggcac tggcggctga ctgcgcctgc aacaatacgg cattaagatc
     8881 ggcttctgcg gcgcgctgcg cagttcttgc acggtcaacg tcttccgctg agacaaaacc
     8941 ttctttcagt aatggctcgg tgcggcgtaa tgtatctgtg gcctgtttcg cggcggcacg
     9001 ggctttttct accgtggcat taaccgagtc ggcaccaaac tgttgcgcgt caacgctacg
     9061 ttgggtgagc ataatttgct tatccagcgc cgcgagggag gcttcggctt tcgccagatt
     9121 ggcttcgtac gggcgcgggt cgatgcggaa cagcaaatcg ccctgtttca ccgcctggtt
     9181 gtcggtgacc gccagttcta caatgcgacc gctgacttcc ggcaccacat caatggtatc
     9241 tgctgacgcg taggcgtcat tagttgatgg cgcactgtct acgcgccaga taacgaaaac
     9301 aagggcaacc agcgccaacg caaccactaa cagagcaggg aatttactgc gaggagcttt
     9361 tttcggcgta ctttccatga gcgcgtctca aatagattag aaaaatgcca gccagaacag
     9421 catggcgtag agagcaaaaa gggcggtata aataattccg acaaatgcca gattgatatt
     9481 tgccctctga ataattcgcc tcgtgatgag cgtcaaaata aggctggcaa tggcgcagaa
     9541 aaaccagctg ggataataag cgccgatcac cgggattgcc ggagataatg agcatcccga
     9601 aaccatgaag acgggaatta tccaggctgt ttttttgagt tgcatcgcca tgcgagagag
     9661 aactgttggc atattaaata catcctgtct gctgcgaaca atatctgtag tgaatatcaa
     9721 tatccattga aggcgtcagt atggctattt tctcgatgaa taaaaatagc tttattcagc
     9781 caccgcattc ataacttata tattttattt attaat
//
LOCUS       DADXDL010000133         9378 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.133, whole genome shotgun sequence.
ACCESSION   DADXDL010000133 DADXDL010000000
VERSION     DADXDL010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9378)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9378)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9378
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.133"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(47..832)
                     /locus_tag="IRB70_004385"
     CDS             complement(47..832)
                     /locus_tag="IRB70_004385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634224.1"
                     /translation="MNSKKVCCICVLFSLLAGCASESSIDEKKKKAQVTQSNINKNTP
                     LQLTDKDLFGNETTLAVSEEDIQAALDGNEFRVPLNSPVILVQSGNRAPETIMQEEMR
                     KYYTVSTFSGIPDRQKPLTCNKNKDKNENEDVASAENMNWMQALRFVAAKGHQKAIIV
                     YHDTLQTGKYDTALKSTVWSDYKNEKITNTISLRYLVRFTLVDVTTGEWAAWSPVNYE
                     YKVLPPLPGKNEASTTDMTEQQIMQLKQKTYKAMVKDLVNRYQ"
     gene            complement(1158..1234)
                     /locus_tag="IRB70_004386"
     tRNA            complement(1158..1234)
                     /locus_tag="IRB70_004386"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1198..1200),aa:Asp,seq:gtc)
     gene            complement(1367..2098)
                     /gene="dnaQ"
                     /locus_tag="IRB70_004387"
     CDS             complement(1367..2098)
                     /gene="dnaQ"
                     /locus_tag="IRB70_004387"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706156.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit epsilon"
                     /protein_id="HBC0634225.1"
                     /translation="MSTAITRQIVLDTETTGMNQIGAHYEGHKIIEIGAVEVVNRRLT
                     GNNFHVYLKPDRLVDPEAFGVHGIADEFLLDKPTFAEVADEFMDYIRGAELVIHNAAF
                     DIGFMDYEFSLLKRDIPKTNTFCKVTDSLAVARKMFPGKRNSLDALCARYEIDNSKRT
                     LHGALLDAQILAELYLAMTGGQTSMAFAMEGETQQQQGETTIQRIVRQASKLRVVFAT
                     DEELAAHEARLDLVQKKGGSCLWRA"
     gene            2163..2630
                     /gene="rnhA"
                     /locus_tag="IRB70_004388"
     CDS             2163..2630
                     /gene="rnhA"
                     /locus_tag="IRB70_004388"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI"
                     /protein_id="HBC0634226.1"
                     /translation="MLKQVEIFTDGSCLGNPGPGGYGAILRYRGREKTFSAGYTRTTN
                     NRMELMAAIVALEALKEHCEVILSTDSQYVRQGITQWIHNWKKRGWKTADKKPVKNVD
                     LWQRLDAALGQHQIKWEWVKGHAGHPENERCDELARAAAMNPTLEDTGYQVEV"
     gene            complement(2627..3349)
                     /locus_tag="IRB70_004389"
     CDS             complement(2627..3349)
                     /locus_tag="IRB70_004389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414749.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBC0634227.1"
                     /translation="MKPARVPQTVVAPDCWGDLPWGELYRKALERQLNPWFTKMYGFH
                     LLKIGNLSAEINCEACAVSHQVNVSAQGLPVQVQADPLHLPFADKSVDVCLLAHTLPW
                     CTDPHRLLREADRVLIDDGWLVISGFNPISLMGLRKLVPVLRKTSPYNSRMFTLMRQL
                     DWLSLLNFEVLHASRFHVLPWNKHGGKLLNAHIPALGCLQLIVARKRTIPLTLNPMKQ
                     SKNKPRIRQAVGATRQCRKPQA"
     gene            3383..4138
                     /gene="gloB"
                     /locus_tag="IRB70_004390"
     CDS             3383..4138
                     /gene="gloB"
                     /locus_tag="IRB70_004390"
                     /EC_number="3.1.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacylglutathione hydrolase"
                     /protein_id="HBC0634228.1"
                     /translation="MNLNSIPAFDDNYIWVLNDEAGRCLIVDPGDAEPVLNAIAANNW
                     QPEAIFLTHHHHDHVGGVKELVKKFPQIVVYGPQETQDKGTTQVVKDGETAFVLGHEF
                     SVIATPGHTLGHICYFSKPYLFCGDTLFSGGCGRLFEGTPSQMYQSLKKLSALPDDTL
                     VCCAHEYTLSNMKFALSILPHDLSINDYYRKVKELRAKNQITLPVILKNERQINVFLR
                     TEDIDLINVINEETLLQQPEERFAWLRSKKDRF"
     gene            4210..5568
                     /gene="mltD"
                     /locus_tag="IRB70_004391"
     CDS             4210..5568
                     /gene="mltD"
                     /locus_tag="IRB70_004391"
                     /EC_number="4.2.2.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="murein transglycosylase D"
                     /protein_id="HBC0634229.1"
                     /translation="MKAKAILLASVLLVGCQSTGNVQQHAQSLSAAGQGEAAKFTSQA
                     RWMDDGTSIAPDGDLWAFIGDELKMGIPENDRIREQKQKYLRNKSYLHDVTLRAEPYM
                     YWIAGQVKKRNMPMELVLLPIVESAFDPHATSGANAAGIWQIIPSTGRNYGLKQTRNY
                     DARRDVVASTTAALNMMQRLNKMFDGDWLLTVAAYNSGEGRVMKAIKTNKARGKSTDF
                     WSLPLPQETKQYVPKMLALSDILKNSKRYGVRLPTTDESRALARVHLSSPVEMAKVAD
                     MAGISVSKLKTFNAGVKGSTLGASGPQYVMVPKKHADQLRESLASGEIAAVQSTLVAD
                     NTPLNSRVYTVRSGDTLSSIASRLGVSTKDLQQWNKLRGSKLKPGQSLTIGAGSSAQR
                     LANNSDSITYRVRKGDSLSSIAKRHGVNIKDVMRWNSDTANLQPGDKLTLFVKNNNMP
                     DS"
     gene            complement(5616..6386)
                     /locus_tag="IRB70_004392"
     CDS             complement(5616..6386)
                     /locus_tag="IRB70_004392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBC0634230.1"
                     /translation="MTTQSHHDHVEKQFSSQASEYLTSTVHASGRDLQRLAVRLADYP
                     DASVLDMGCGAGHASFVAAQNVSAVVAYDLSAQMLDVVAQAAEAGHLKNIATRQGYAE
                     SLPFADNAFDIVISRYSAHHWHDVGAALREVNRILKPGGRLIVMDVMSPGHPVRDVWL
                     QTVEALRDTSHVRNYASGEWLTLINEANLIVDNLITDKLPLEFSSWVARMRTPEALVD
                     AIRIYQQSASTEVRTYFALQNDGSFTSDIIMVEAHKAA"
     gene            complement(6463..7263)
                     /locus_tag="IRB70_004393"
     CDS             complement(6463..7263)
                     /locus_tag="IRB70_004393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBC0634231.1"
                     /translation="MRKNTYAMRYVAGQPAERILPPGSFASIGQALPPGEPLSTEERI
                     RILVWNIYKQQRAEWLSVLKNYGKDAHLVLLQEAQTTPELVQFATANYLAADQVPAFV
                     LPQHPSGVMTLSAAHPVYCCPLREREPILRLAKSALVTVYPLPDTRLLMVVNIHAVNF
                     SLGVDVYSKQLLPIGDQIAHHSGPVIMAGDFNAWSRRRMNALYRFAREMSLRQVRFTD
                     DQRRRAFGRPLDFVFYRGLNVSEASVLVTRASDHNPLLVEFSPGKPDK"
     gene            7504..8418
                     /locus_tag="IRB70_004394"
     CDS             7504..8418
                     /locus_tag="IRB70_004394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBC0634232.1"
                     /translation="MKATSEELAIFVSVVESGSFSRAAEQLGQANSAVSRAVKKLEMK
                     LGVSLLNRTTRQLSLTEEGERYFRRVQSILQEMAAAESEIMETRNTPRGLLRIDAATP
                     VVLHFLMPLIKPFRERYPEVTLSLVSSETIINLIERKVDVAIRAGTLTDSSLRARPLF
                     NSYRKIIASPDYISRYGKPETIDDLKQHICLGFTEPASLNTWPIACSDGQLHEVKYGL
                     SSNSGETLKQLCLSGNGIACLSDYMIDREIARGELVELMADKVLPVEMPFSAVYYSDR
                     AVSTRIRAFIDFLSEHVKTAPGGAVREA"
     gene            complement(8415..9218)
                     /gene="dkgB"
                     /locus_tag="IRB70_004395"
     CDS             complement(8415..9218)
                     /gene="dkgB"
                     /locus_tag="IRB70_004395"
                     /EC_number="1.1.1.346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,5-didehydrogluconate reductase DkgB"
                     /protein_id="HBC0634233.1"
                     /translation="MAIPAFGLGTFRLKDDVVISSVKTALELGYRAIDTAQIYDNEAA
                     VGQAIAESGVPRHELYITTKIWIENLSKDKLIPSLKESLQKLRIDYVDLTLIHWPSPN
                     DEVSVEEFMQALLEAKKQGLTREIGISNFTIPLMEKAIAAVGAENIATNQIELSPYLQ
                     NRKVVAWAKQHGIHITSYMTLAYGKALKDEVIARIAAKHNATPAQVILAWAMGEGYSV
                     IPSSTKRKNLESNLKAQNLQLDAEDKKAIAALDCNDRLVSPEGLAPEWD"
BASE COUNT         2511 a         2224 c         2222 g         2421 t
ORIGIN      
        1 ttctgtatta ttgccgccag aaattcctgg cggcagatat aatttattat tgatagcggt
       61 taaccaaatc ttttaccatc gctttatagg tcttttgctt aagttgcatg atttgctgct
      121 ctgtcatatc agtcgtactg gcttcattct tgccgggcaa tggtggaagc actttatatt
      181 cataattcac cggcgaccag gcagcccact cacctgtagt tacatccacc agcgtgaatc
      241 gcaccagata gcgcagtgag attgtgttag taattttttc atttttataa tcggaccata
      301 ctgttgattt cagtgcagtg tcatattttc ctgtctgcaa cgtatcatgg taaacaataa
      361 tcgctttctg atgccctttc gcagccacaa aacgcaatgc ctgcatccag ttcatatttt
      421 cagcactggc aacatcctcg ttctcatttt tatctttgtt tttgttacaa gtcagaggct
      481 tttgcctgtc cgggatacca gagaatgtgg aaacagtata atattttcgc atctcctcct
      541 gcataatggt ttccggtgcg cggttgccgg attgaacaag tattacagga gaattaaggg
      601 gaacgcggaa ctcatttcca tcaagcgcag cttgaatatc ctcctcggat acggccagag
      661 tggtttcatt accgaataaa tctttgtctg tcagttgcag gggggtattt ttattaatat
      721 tactttgtgt gacttgagct tttttcttct tttcatcaat agaagattca gaggcacatc
      781 ctgcaagcag cgagaataac acacatatgc aacaaacctt ttttgaattc ataatcggac
      841 actccctcgc ctgtcataat gattagaata tttagcactg ataacgaact ctaattatat
      901 accccactta aataataaca aataaaatca atttgaaata tacattcact taatcaatat
      961 aaaattattc tctgaaaata tatttaagct gaatggctcg atatcattat tgaattttaa
     1021 tgaatgagac aacaagcgag aatcacgcac ttacgctaga gtaaaatcat tgaacagaga
     1081 aatggcggga ttcaaataca aaaaaccgca aaattaaaaa tcttgcggtt ctctgaactc
     1141 attttcatga gtgaatttgg cggaacggac gggactcgaa cccgcgaccc cctgcgtgac
     1201 aggcaggtat tctaaccgac tgaactaccg ctccgcgttg tgttccgttg ggaacgaggc
     1261 gaatattacg gattgcctca cccttcgtca acggtttttc tcatcttttg aatcgtttgc
     1321 tgcaaaaatc gcccaagtcg ctaattttag cgccttttac aggtatttat gcccgccaga
     1381 ggcagcttcc gccctttttc tgcaccagat cgagacgggc ttcatgtgcc gcaagctctt
     1441 catctgtcgc aaaaacaacg cgtaacttgc ttgcctgacg cacaatgcgc tgaattgttg
     1501 tttcaccttg ttgctgttgt gtctctcctt ccatcgcaaa agccatcgac gtttgaccac
     1561 cagtcatcgc cagataaagt tccgcaagga tctgggcatc gagtaatgcc ccgtgcaacg
     1621 ttcgtttact gttatctatt tcgtagcggg cacataacgc atcgaggctg ttgcgcttac
     1681 cgggaaacat tttcctcgcc accgcaaggc tatcggtgac cttacagaag gtattggtct
     1741 tcggaatatc gcgcttaagc aacgaaaact cgtagtccat aaagccgata tcgaacgctg
     1801 cgttatggat caccagctcc gcgccgcgga tatagtccat gaactcatcg gctacctctg
     1861 caaacgtggg cttatcgagc aaaaattcat cggcaatacc atgtacgcca aaggcttccg
     1921 gatccaccag ccgatcgggt ttgagataaa catggaagtt attgcccgtc aggcgacggt
     1981 tcaccacttc aacggcacca atctcaatga tcttgtggcc ttcatagtgc gcaccaatct
     2041 ggttcatacc ggtagtttcg gtatcgagaa cgatctggcg tgtaattgca gtgctcatag
     2101 cggtcattta tgtcagactt gtcgttttac agttcgattc aattacagga agtctaccag
     2161 agatgcttaa acaggtagaa attttcaccg atggttcgtg tctgggtaat cctggacctg
     2221 ggggttacgg cgctatttta cgctatcgcg gacgcgagaa aacctttagc gcaggctaca
     2281 cccgcaccac caacaaccgt atggagttga tggccgctat tgtcgcgctg gaggcgttaa
     2341 aagaacattg cgaagtcatt ttgagtaccg acagccagta tgtccgccag ggtatcaccc
     2401 agtggatcca taactggaaa aaacgtggct ggaaaacagc agacaaaaaa ccagtaaaaa
     2461 atgtcgatct ctggcaacgt cttgatgctg cgctggggca gcatcaaatc aaatgggaat
     2521 gggttaaagg ccatgccggt catccagaaa acgaacgttg cgatgaactg gctcgtgccg
     2581 cagcgatgaa tcccacactg gaagatacgg gctatcaagt cgaagtttaa gcctgtggtt
     2641 tacgacattg ccgggtggct ccaaccgcct ggcgaattcg tggcttgttt ttactctgtt
     2701 tcatcggatt tagcgttaaa ggaatagtcc gtttccgggc gacaataagt tgtaagcaac
     2761 caagcgcagg aatatgcgca ttcaatagtt ttccaccgtg tttgttccac gggagaacgt
     2821 ggaaacggct ggcgtgtagc acttcaaaat tcaacaaaga gagccagtcc agctgccgca
     2881 tcagagtaaa catccggctg ttatagggcg aggttttgcg caataccggt acaagtttgc
     2941 gtaatcccat taaacttatg ggattgaagc cactaatcac cagccagcca tcatcaatca
     3001 gtacccgatc ggcttcacgc aataaacgat gcggatcggt gcaccacggc aatgtatgtg
     3061 ccagtagaca aacatcaacg gatttatcgg caaaaggaag atgaagtggg tccgcctgca
     3121 cctggacggg cagtccttgc gcagaaacat tcacttgatg agaaaccgcg cacgcttcgc
     3181 aattgatttc tgcgcttaaa ttgccaatct taagcagatg aaaaccatac attttagtga
     3241 accacgggtt gagctggcgc tccagcgcct tgcgataaag ctctccccag ggcaaatcgc
     3301 cccagcaatc aggagccacg acagtttgag ggactcttgc cggtttcatc acaaccttcc
     3361 gtttcacact gagaggtaat ctatgaatct taacagtatt cccgcctttg atgacaatta
     3421 catctgggtt ttgaatgatg aagcaggtcg ctgcctgatt gtcgatcccg gagacgcaga
     3481 gccagtatta aacgccattg ccgccaataa ctggcaaccg gaggccatat ttctcaccca
     3541 ccatcaccac gatcacgttg gcggcgtaaa agaactggtg aaaaagtttc cgcaaattgt
     3601 ggtgtatggt ccacaagaga cacaagataa gggaacaaca caggtagtca aagatggcga
     3661 aactgccttc gttttagggc atgaatttag tgtaattgcc acaccgggtc acactttagg
     3721 acatatctgt tacttcagta aaccttatct attttgcggc gacacgctgt tttctggtgg
     3781 gtgtggtcgg ttgtttgaag ggacaccatc acaaatgtat caatcactta aaaagttaag
     3841 tgcgttacct gacgatacat tggtatgttg tgctcatgaa tataccttat caaatatgaa
     3901 gtttgctttg agtattcttc cgcacgattt gtccataaat gattattatc gtaaagttaa
     3961 ggagttacgg gcaaaaaatc aaataacact acccgtaatt ctgaaaaatg agcggcaaat
     4021 taatgttttt ttaagaacgg aagatattga tttaattaat gtaattaatg aagaaacatt
     4081 attgcaacaa cctgaagaac gttttgcatg gttaaggtca aagaaagata ggttctgata
     4141 aaactttctt gtcatcggct ccgttcgccg ttatgatcgg tcgtctttta agcaactatt
     4201 gacacacaca tgaaggcaaa agcgatatta ctcgcctctg tcctgctcgt gggttgccag
     4261 agcaccggca acgttcaaca gcacgcacag agcctttctg cagctggtca aggggaagca
     4321 gcaaagttta caagtcaggc acgatggatg gacgatggga cgtctatcgc gccagatggt
     4381 gacttgtggg ctttcattgg cgacgagcta aagatgggaa ttccggaaaa cgaccggatt
     4441 cgcgaacaga aacagaaata tttacgcaat aagagctatc tccacgatgt aactttacgg
     4501 gcagagccgt atatgtactg gatagccggg caagttaaaa aacgtaacat gcctatggaa
     4561 ctggtactac tacccatagt ggagagcgct tttgatcctc acgcaacgtc tggcgccaat
     4621 gccgcgggca tctggcagat cattccgagc acggggcgca attatggttt gaaacagacc
     4681 cgcaattatg acgcgcgtcg cgatgttgtt gcttcaacaa ctgccgcgct gaacatgatg
     4741 cagcgtctga acaagatgtt tgacggcgac tggcttctga ccgtagcggc ttataacagc
     4801 ggcgaaggtc gggtcatgaa ggcaattaaa acgaacaaag cgcgtgggaa atccacggac
     4861 ttctggtcgt taccgttgcc gcaggaaacg aagcagtacg tgcctaaaat gctggcattg
     4921 agtgatattc tcaaaaacag caagcgttat ggcgtacgtc tgccaacgac cgatgaaagc
     4981 cgtgctctgg cgcgtgtgca cctgagcagc ccggttgaaa tggcgaaggt tgcagatatg
     5041 gcggggattt ccgtcagcaa gctgaagaca ttcaacgcag gcgtgaaagg ctccacgctg
     5101 ggcgcaagtg gtccgcagta cgtgatggtg ccaaagaagc atgcagatca actgcgtgaa
     5161 tctctggctt caggcgaaat tgctgctgta cagtcgacgc tggttgccga caatacgccg
     5221 cttaacagcc gtgtttacac cgtacgctct ggcgacacgc tttcaagtat cgcttcacgt
     5281 ctcggcgtaa gcaccaaaga tttgcagcag tggaacaaac tgcgcggatc taagctgaag
     5341 ccaggccaaa gtttgacgat tggcgcaggc agtagcgcac agcgactggc aaacaacagc
     5401 gatagcatta cgtatcgtgt gcgcaaaggc gattcgcttt caagcattgc taaacgccac
     5461 ggcgtgaaca tcaaagatgt gatgcgctgg aacagcgaca ctgcgaatct gcaaccaggc
     5521 gataagctga cgttgtttgt gaaaaacaac aacatgccag attcctgaca aatcagataa
     5581 tcaaaaggca ccgattcccc cggtgccttt tttatttatg ccgctttatg tgcttctacc
     5641 atgatgatat cactggtgaa agagccgtca ttctgcaagg caaaatacgt tctcacctct
     5701 gtcgatgcgc tctgttggta aatgcgaata gcgtctacta acgcttctgg cgtacgcatt
     5761 ctcgcgaccc atgaagaaaa ttccagcggt aacttatctg taattaaatt atcaactatc
     5821 agattggctt cattgattaa cgtcaaccac tcaccgctgg cgtagtttcg tacgtgagag
     5881 gtatcgcgta atgcttctac cgtctgtaac cagacgtcgc gcactgggtg acccggagac
     5941 attacgtcca tcacaatcag cctaccgcca ggtttcaata tcctattcac ttctcgcagt
     6001 gctgcaccaa catcatgcca gtgatgggca gaataacggc tgataacaat atcaaatgcg
     6061 ttatcggcaa atggcagact ttcggcatat ccctggcggg tggcgatatt tttcaggtgc
     6121 ccggcttcgg cagcttgtgc cacgacatcc agcatttggg cagataagtc atacgccacc
     6181 accgcgctca cgttttgcgc agcgacaaag ctggcatgcc ctgctccgca gcccatatca
     6241 agtacgcttg catcaggata atcagccaga cgcaccgcca ggcgctgtaa atctcgcccg
     6301 gatgcatgta cggtactggt taaatactca ctggcctgcg agctaaactg cttttctacg
     6361 tggtcatggt gggattgtgt tgtcattgcg ctgtcctttt attgtttgat taaaaagggc
     6421 agcgccaaac gttggtctgc cctgtggcag acctgacata ccttatttat caggcttgcc
     6481 gggactgaat tcaacgagta gcggattgtg atcggaagcg cgcgtaacca gtacagaagc
     6541 ttcgctgacg ttcagaccac ggtagaaaac aaaatcgagc gggcggccaa acgcccgacg
     6601 gcgctgatca tcggtaaaac gcacctggcg cagcgacatt tcccgcgcaa agcgatataa
     6661 cgcgttcatc cttctacggc tccaggcatt gaaatctccc gccataatga ccgggccgct
     6721 gtggtgagct atctgatcgc caataggaag taactgctta ctatagacat ccacgcccaa
     6781 actgaaattg acggcgtgta tattaaccac catcaacagg cgggtgtcag gcaatggata
     6841 gaccgtcacc agggccgact tcgccagacg caaaatgggt tctcgttcac gtaacgggca
     6901 gcaatacact ggatgcgccg ccgaaagggt cattacaccg gaaggatgtt gtggcagcac
     6961 gaaagcgggt acctgatcgg cggcaagata gttagcggtc gcaaactgta ctaactctgg
     7021 cgttgtctgc gcttcctgca ataacaccag atgtgcatct ttgccgtagt tctttaatac
     7081 cgacaaccat tcagcgcgtt gctgtttgta tatgttccac accaggatcc gaatacgctc
     7141 ttcggtactt aacggttctc caggtggtaa tgcctggccg atgctcgcaa aagaccccgg
     7201 cggtaagatc ctttccgcag gttgtccggc aacatagcgc atggcatagg tgttttttcg
     7261 cacttttgac tttgaaacct ctattacgtc aacccttccg cactcgggag ggttctactg
     7321 ttatagggat tttagctcac tctttcaacg agcaattgta tattgctatg taagcaagtg
     7381 cttacaccgg tcagaaattt gctcattatt gagaacatta aatcggatga catatctcgc
     7441 atcctgatgg tttaatgaca aataaattca aaatatctct tctattttgc aacaggagca
     7501 aaaatgaaag ccacgtcgga agaactcgcc atttttgttt cagtcgtcga aagcggcagc
     7561 tttagccggg cagcggaaca attagggcaa gcaaactcag cggtaagccg ggcggtgaaa
     7621 aagctggaga tgaaacttgg cgttagcctg cttaatcgga ccacgcgaca acttagcctg
     7681 acggaagaag gcgagcgtta ttttcgtcgc gtacagtcaa ttttgcagga gatggcagcg
     7741 gcagaatcag aaattatgga gacgcgtaat acaccgcgtg gactgttacg gatcgatgcc
     7801 gcaactccag tggtgctgca ctttctgatg ccgttgatta agccttttcg tgaacgctat
     7861 ccggaagtca ctttatcgct agtctcctcc gaaacgatta ttaatttgat cgaaagaaaa
     7921 gtggatgtcg cgatacgcgc cggtacgtta acggattcca gcttacgtgc caggccgtta
     7981 tttaacagtt atcgaaaaat tatcgcctcc cccgattata tttcccgcta cgggaagcca
     8041 gaaacgatcg acgatttaaa gcaacatatt tgcctgggat tcactgaacc cgcttccctc
     8101 aatacctggc cgatagcctg tagtgatgga caattacatg aggtgaagta cggtttgtca
     8161 tccaatagtg gggaaacact gaaacagctt tgcctgagtg gcaacgggat tgcgtgtttg
     8221 tccgactaca tgatcgacag agaaatcgct cgcggagaat tggtggagtt aatggcagat
     8281 aaagtattgc cagtggaaat gccattcagt gccgtatatt acagcgaccg tgcggtaagt
     8341 acacgcatcc gggcttttat cgatttcctt agcgagcatg taaaaacagc tcccggagga
     8401 gctgtcagag aggcttaatc ccattcagga gccagacctt ccgggctaac caggcggtcg
     8461 ttgcaatcca gtgcggcgat cgctttttta tcttcggcat caagctgtaa attttgtgcc
     8521 ttaagattac tttccaggtt tttacgttta gtagaagaag gaattacgga gtaaccttcc
     8581 cccatagccc acgccagaat cacttgtgcc ggagtcgcat tgtgtttagc tgcgatacga
     8641 gcaataacct catctttcag ggccttacca tacgccagcg tcatatagga agtaatatgg
     8701 atgccgtgct gtttagccca ggcgaccact ttacggtttt gcagataagg tgagagttca
     8761 atctggttag tagcgatgtt ttcagcgcca acagcagcaa tcgccttttc catcaatggg
     8821 atcgtgaagt tggaaatacc gatctcacgc gtcagccctt gttttttggc ttccagcagc
     8881 gcctgcataa actcttcaac agagacttca tcgtttggtg acggccagtg gattagcgtc
     8941 agatcaacat aatcgatacg caatttttgc aggctctctt tcagactcgg gatcaatttg
     9001 tctttgctga gattttcaat ccagatttta gtggtgatgt agagttcatg acgtggcacg
     9061 ccactttctg caatcgcctg acctactgcg gcttcgttat catagatttg tgcggtatca
     9121 attgcgcgat aaccaagttc aagcgccgtt ttcacagatg aaataacaac gtcgtctttc
     9181 agacggaaag tacctaaacc aaatgcaggg atagccataa tatgcctctt ttaatgctat
     9241 tttcgttaac tgaagtgatt atgggcttta gaatgttgcg gaaaaagggc gtaaaacgca
     9301 gaggattttt gcgatttaag caataataga aatatagacg aaaaaaaacc tcgagcgtta
     9361 actcgaggct tcttaata
//
LOCUS       DADXDL010000134         9288 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.134, whole genome shotgun sequence.
ACCESSION   DADXDL010000134 DADXDL010000000
VERSION     DADXDL010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9288
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.134"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..313
                     /gene="appY"
                     /locus_tag="IRB70_004396"
     CDS             <1..313
                     /gene="appY"
                     /locus_tag="IRB70_004396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DNA-binding transcriptional activator AppY"
                     /protein_id="HBC0634234.1"
                     /translation="FNIERQWHLKDIAELIYTSESLIKKRLRDEGTSFTEILRDTRMR
                     YAKKLITSNSYSINVVAQKCGYNSTSYFICAFKDYYGVTPSHYFEKIIGVTDGINKTI
                     D"
     gene            complement(562..1515)
                     /gene="ompT"
                     /locus_tag="IRB70_004397"
     CDS             complement(562..1515)
                     /gene="ompT"
                     /locus_tag="IRB70_004397"
                     /EC_number="3.4.23.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease OmpT"
                     /protein_id="HBC0634235.1"
                     /translation="MRAKLLGIVLTTPIAISSFASTETLSFTPDNINADISLGTLSGK
                     TKERVYLAEEGGRKVSQLDWKFNNAAIIKGAINWDLMPQISIGAAGWTTLGSRGGNMV
                     DQDWMDSSNPGTWTDESRHPDTQLNYANEFDLNIKGWLLNEPNYRLGLMAGYQESRYS
                     FTARGGSYIYSSEEGFRDDIGSFPNGERAIGYKQRFKMPYIGLTGSYRYEDFELGGTF
                     KYSGWVEASDNDEHYDPGKRITYRSKVKDQNYYSVAVNAGYYVTPNAKVYVEGAWNRV
                     TNKKGNTSLYDHNDNTSDYSKNGAGIENYNFITTAGLKYTF"
     gene            complement(2028..2789)
                     /gene="envY"
                     /locus_tag="IRB70_004398"
     CDS             complement(2028..2789)
                     /gene="envY"
                     /locus_tag="IRB70_004398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator EnvY"
                     /protein_id="HBC0634236.1"
                     /translation="MQLSSSEPCVVILTEKEVEVSVNNHATFTLPKNYLAAFACNNNV
                     IELSTLNHVLITHINRNIINDYLLFLNKNLTCIKPWSRLATPVIACHSRTPEVFRLAA
                     NHSKQQPSKPCEAELTRALLFTVLSNFLEQSRFIALLMYILRSSVRDSVCRIIQSDIQ
                     HYWNLRIVASSLCLSPSLLKKKLKNENTSYSQIVTECRMRYAVQMLLMDNKNITQVAQ
                     LCGYSSTSYFISVFKAFYGLTPLNYLAKQRQKVMW"
     gene            complement(2972..3862)
                     /locus_tag="IRB70_004399"
     CDS             complement(2972..3862)
                     /locus_tag="IRB70_004399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4434 family protein"
                     /protein_id="HBC0634237.1"
                     /translation="MRKFIFVLLTLLLVSPFSFAMKGIIWQPQNRDSQVTDTQWQGLM
                     SQLRLQGFDTLVLQWTRYGDAFTQPEQHALLFKRAAAAQQAGLKLIVGLNADPEFFMH
                     QKQSSAALESYLNRLLAADLQQARLWSAVPGVTPDGWYISAEIDDLNWRSEAARQPLL
                     TWLNNAQRLISDVSAKPVYISSFFAGNMSPDGYRQLLEHVKATGVNVWVQDGSGVDKL
                     TAEQRERYLQASADCQSSAPASGIVYELFVAGKGKTFTAKPKPDAEIASLLAKRSSCG
                     KDTLYFSLRYLPVAHGILEY"
     gene            complement(3863..6835)
                     /gene="nfrA"
                     /locus_tag="IRB70_004400"
     CDS             complement(3863..6835)
                     /gene="nfrA"
                     /locus_tag="IRB70_004400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage adsorption protein NfrA"
                     /protein_id="HBC0634238.1"
                     /translation="MKENNLNRVIGWSGLLLTSLLSTSALADNIGTSAEELGLSDYRH
                     FVIYPRLDKALKAQKNNDEATAIREFEYIHQQVPDNIPLTLYLAEAYRHFGHDDRARL
                     LLEDQLKRHPGDARLERSLAAIPVEVKSVTTVEELLAQQKACDAAPTLRCRSEVGQNA
                     LRLAQLPVARAQLNDATFAASPEGKTLRTDLLQRAIYLKQWSQADTLYNEARQQNTLS
                     AAERRQWFDVLLAAQLDDRILALQSQGIFTDPQSYITYATALAYRGEKARLQHYLIEN
                     KPLFTTDAQEKSWLYLLSKYSVNPVQALANYTVQFADNRQYVVGATLPVLLKEGQYDA
                     AQKLLATLPANEMLEERYTVSVATHNKAEALRLARLLYQQEPANLTRLDQLTWQLMQN
                     EQSREAADLLLQRYPFQGDARVSQTLMARLASLLESHPYLATPAKVAILSKPLPLAEQ
                     RQWQSQLPGIADNCPAIVRLLGDMSPSYDAAAWNRLAKCYRDTLPGVALYAWLQAEQR
                     QPNAWQHRAVAYQAYQVEDYATALAAWQKISLHDMSNEDLLAAANTAQAAGNGAARDR
                     WLQQAEQRGLGNNALYWWLHAQRYIPGQPELALNDLTRSINIAPSANAYVARATIYRQ
                     RHNVPAAVSDLRAALELEPNNSNTQAALGYALWDSGDIAQSREMLEQAHKGLPDDPAL
                     IRQLAYVNQRLDDMPATQHYARLVIDDIDNQALITPLTPEQNQQRFNFRRLHEEVGRR
                     WTFSFDSSIGLRSGAISTANNNVGGAAPGKSYRSYGQLEAEYRIGRNMLLEGDLLSVY
                     SRVFADTGENGVMMPVKNPMSGTGLRWKPLRDQIFFLAVEQQLPLNGQNGASDTMLRA
                     SASFFNGGKYSDEWHPNGSGWFAQNLYLDAAQYIRQDIQAWTADYRVSWHQKVANGQT
                     IEPYAHVQDNGYRDKGTQGAQLGGVGVRWNIWTGETHYDAWPHKVSLGVEYQHTFKAI
                     NQRNGERNNAFLTIGVHW"
     gene            complement(6822..9059)
                     /gene="nrfB"
                     /locus_tag="IRB70_004401"
     CDS             complement(6822..9059)
                     /gene="nrfB"
                     /locus_tag="IRB70_004401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage adsorption protein NrfB"
                     /protein_id="HBC0634239.1"
                     /translation="MDWLLDVFATWLYGLKVIAITLAVIMFISGLDDFFIDVVYWVRR
                     IKRKLSVYRRYPRMSYRELYKPDEKPLAIMVPAWNETGVIGNMAELAATTLDYENYHI
                     FVGTYPNDPDTQRDVDEVCARFPNVHKVVCARPGPTSKADCLNNVLDAITQFERSANF
                     AFAGFILHDAEDVISPMELRLFNYLVERKDLIQIPVYPFEREWTHFTSMTYIDEFSEL
                     HGKDVPVREALAGQVPSAGVGTCFSRRAVTALLADGDGIAFDVQSLTEDYDIGFRLKE
                     KGMTEIFVRFPVVDEAKEREQRKFLQHARTSNMICVREYFPDTFSTAVRQKSRWIIGI
                     VFQGFKTHKWTSSLTLNYFLWRDRKGAISNFVSFLAMLVMIQLLLLLAYESLWPDAWH
                     FLSIFSGSAWLMTLLWLNFGLMVNRIVQRVIFVTGYYGLTQGLLSVLRLFWGNLINFM
                     ANWRALKQVLQHGDPRRVAWDKTTHDFPSVTGDTRSLRPLGQILLENQVITEEQLDTA
                     LRNRVEGLRLGGSMLMQGLISAEQLAQALAEQNGVAWESIDAWQIPSSLIAEMPASVA
                     LHYAVLPLRLENDELIVGSEDGIDPVSLAALTRKVGRKVRYVIVLRGQIVTGLRHWYA
                     RRRGHDPRAMLYNAVQHQWLTEQQAGEIWRQYVPHQFLFAEILTTLGHINRSAINVLL
                     LHHERSSLPLGKFLVTEGVISQETLDRVLTIQRELQVSMQSLLLKAGLNTEKVAQLES
                     ENEGE"
BASE COUNT         2243 a         2265 c         2319 g         2461 t
ORIGIN      
        1 ttttaatatt gagcggcaat ggcatttaaa agatattgcg gaattgattt atacgagtga
       61 aagtttaata aaaaaaagat taagggatga aggaacgtca tttactgaaa tattgagaga
      121 tactaggatg aggtatgcaa aaaaactcat aacttcaaac tcttattcta tcaatgtcgt
      181 agcccagaaa tgtggctata acagtacttc atatttcata tgtgcattta aagattatta
      241 tggtgtcacg ccatctcatt attttgagaa aataatcggc gtcacagatg gaataaacaa
      301 aacaattgac tgataatgtt tattacaagt tgcctacatg ttaattataa tattatacag
      361 cgtttttttg atgtgatatt ctggaaccat taatttgtaa ttgggttgct gtcgcctatt
      421 ttatacatgc tataattgat ggttttctat gtgatttagt taataacctt ctgggtttat
      481 tttaagggtt aattgttaca ttgaaatggc tagttattcc ccggggcgat tgtcacctcg
      541 gggaaatttt agttggcgtt cttaaaatgt gtacttaaga ccagcagtag tgatgaagtt
      601 atagttttct atgcctgcac catttttgct gtagtctgaa gtgttatcat tgtgatcata
      661 aagtgaagta ttaccttttt tattcgtaac ccgattccat gcgccttcaa cataaacttt
      721 tgcgttaggt gttacgtaat aacctgcatt gactgcaaca gaatagtaat tttggtcttt
      781 gactttactg cgataagtga ttctttttcc tgggtcatag tgctcatcgt tatcagatgc
      841 ttccacccag ccgctgtatt taaatgtgcc acctagctca aaatcttcat aacgataact
      901 tccagtcaag ccaatgtagg gcattttaaa acgttgtttg tagccgattg ctctttctcc
      961 attcgggaag gagccgatat catctctgaa tccctcctca gaactgtaga tataggaacc
     1021 acctctggct gtaaagctat aacggctttc ctgatatccg gccatgagtc ccaggcggta
     1081 attgggttcg ttgaggagcc agcctttgat attcagatca aattcgttgg cataattgag
     1141 ttgtgtatca gggtgcctac tttcatctgt ccaggttccg gggttactgg aatccatcca
     1201 gtcctgatcg accatattgc cacctcggct gccgagagta gtccagcccg cagccccaat
     1261 agatatctgg ggcatcaaat cccaattaat tgcaccttta ataattgcag cgttattgaa
     1321 tttccagtcg agttgactga cttttcggcc tccttcttcg gctagataaa cacgctcttt
     1381 tgtttttccg ctcagagttc caagactaat gtccgcattt atgttgtcag gagtaaacga
     1441 taaagtctcg gtagaagcaa aagagctgat cgcaataggg gttgtcagga ctattcccag
     1501 aagtttcgcc cgcataaaag ttctccattc aatcgtttta atgattgaat atgtattttt
     1561 tatatctaac ttaatgagtc aattacatat tgctccactg tttatatttt gtttagtatt
     1621 gaatgattat cacaatgcgc tatctgtttt tggtttaatt atctgttatt gtttcatatt
     1681 gcggttttac tgtgtggttt ttttatgctt ttgtggtgct tttatctatt taagtgccat
     1741 gcctttagag gcatataagc gaaaatagca tgaggtttat cctcaattac tatgtttttt
     1801 agtacaaaaa agagggacaa aactgagaca cataaggcct cacaatggct tgcaaggctt
     1861 tacatgtttt gaggtagtgg gacgtgtgag cgcagagatg gcgcggtaag ttgttgactt
     1921 aaaatgtcgt tctaggaact tctaagtcgt gggccgcagg ttcgaatcct gcagggcgcg
     1981 ccatttcttc ttcatttaat cccgtcttat ccgttccgct ttgctcttca ccacatcact
     2041 ttttgtcgct gtttggcgag ataattcaac ggtgtcaggc cgtaaaacgc cttaaaaaca
     2101 gagataaagt acgacgtgct gctatagcca cataattgcg ccacctgagt gatatttttg
     2161 ttatccatca ataacatctg tacggcgtaa cgcatacgac actctgtgac aatctggcta
     2221 tagctggtat tttcgttttt taatttcttt ttgagcaggc tggggcttaa acatagcgaa
     2281 ctggcgacaa ttcgcagatt ccagtaatgc tgaatatcgc tttgaataat gcggcagacg
     2341 ctgtcgcgga cgctgctgcg taagatatac atcagtaggg caataaaccg cgattgctca
     2401 agaaagttag acaatacggt aaaaagcaat gcgcgcgtca actccgcttc gcagggtttg
     2461 ctgggttgct gcttgctgtg gttggcggct agccggaaca cttccggtgt acggctatga
     2521 caagcgataa ccggggttgc cagccgcgac cagggcttta tacaggttaa gttcttattt
     2581 aaaaacaaca gataatcgtt gatgatgtta cggttgatgt gggtgattaa tacgtgattt
     2641 aacgttgaga gttcaatgac gttattgttg cacgcgaagg cggccaggta gtttttcgga
     2701 agggtaaacg tagcatggtt attgacgctt acctctacct ctttttcggt caggatcacc
     2761 acgcaaggtt cactgctgct caattgcatt tcgcactcct cagatatcag aaactccgct
     2821 caaaggatct atgcttcctg catgagtgat cggcccgttc gccgataacg atcttctttc
     2881 tttagcacgc tttttagcaa ttaatcttga tggaattctg acgagagcga aagaggtaag
     2941 ccaggtcgta cccgacttac ctggaggaga tttaatactc gagaatgccg tgcgcgacgg
     3001 gcaaatagcg cagagagaaa tagagcgtgt ctttaccgca agaggaacgt ttcgctaaca
     3061 gcgaggcaat ttctgcgtcc ggtttcggtt tcgctgtaaa ggttttgcct ttgccggcga
     3121 caaacagttc ataaacaatg ccgcttgctg gggcggagct ttggcaatcg gcgctggcct
     3181 gtagataacg ttcacgctgt tcagcggtca gtttatccac gccgctgcca tcctgtaccc
     3241 agacattaac gccggttgct ttaacgtgtt ccagcagttg gcgatagcca tcgggcgaca
     3301 tgtttccggc gaaaaaacta ctgatataaa ccggttttgc tgaaacatcg ctaatcaacc
     3361 gctgcgcgtt gtttaaccat gttagcaaag gctgacgggc ggcttcgctg cgccagttca
     3421 ggtcgtcaat ttccgcgctg atgtaccagc catccggcgt tacgccaggt acggcgctcc
     3481 ataatctggc ttgctggaga tcggcagcca gcaggcggtt aagatagctt tccagcgctg
     3541 cagacgactg tttctggtgc ataaaaaatt ccggatcggc attcagcccg acaatcagct
     3601 tcaggccagc ctgttgcgca gctgcggcac gcttaaacaa taacgcgtgc tgttctggct
     3661 gggtgaatgc atcgccgtaa cgagtccatt gcaaaaccag ggtatcgaag ccttgcaaac
     3721 gtaactgact catcagcccc tgccactggg tatcggtaac ctgactatca cggttttgtg
     3781 gttgccagat aatacctttc atcgcaaagg aaaaagggct gaccaaaagc agtgtcagca
     3841 atacgaaaat gaacttacgc atttaccagt gcactccaat ggtgagaaac gcattgttgc
     3901 gctctccgtt acgttgatta atcgccttaa aggtatgttg atactcgacg ccgagactga
     3961 ctttgtgcgg ccaggcgtcg tagtgcgtct cgccggtcca gatattccag cggaccccga
     4021 caccgccaag ctgcgcgccc tgagtgcctt tatcacgata gccgttgtcc tgaacgtgag
     4081 cgtaaggctc aatagtctgt ccgttagcta ccttctgatg ccagctgacg cgataatctg
     4141 ccgtccacgc ctgaatatcc tggcggatat attgcgctgc atcgaggtac aggttttggg
     4201 caaaccagcc tgaaccgttc gggtgccatt cgtcgctgta tttgccgcca ttaaagaatg
     4261 aggcgctggc gcgcagcatg gtatcggatg cgccattttg cccgttcagc ggcaactgct
     4321 gttcgacggc gaggaaaaag atctgatcgc gcagcggctt ccagcgcaga ccggtgccgg
     4381 acatcggatt tttcaccggc atcatcaccc cgttttctcc agtatcggca aatacacggc
     4441 tgtaaaccga gagcaggtcg ccttccagca gcatattgcg tccgatgcga tactcggctt
     4501 ccagttgccc gtagctacga tagcttttcc ctggcgctgc gccgccgaca ttattgttag
     4561 cggtacttat tgcgccggaa cgcaagccga tagaagaatc gaaactgaac gtccagcggc
     4621 gaccgacctc ctcatgcaga cggcggaaat tgaagcgttg ctgattttgc tctggggtca
     4681 gtggggttat cagcgcctga ttatcaatgt catcaatcac cagccgggcg tagtgctgcg
     4741 tcgcaggcat gtcatccaga cgctggttca cgtaggccag ttgtcggata agtgccggat
     4801 cgtccggtag ccctttatgc gcctgttcga gcatttcccg cgactgtgcg atatcaccgc
     4861 tatcccacaa ggcgtaaccg agcgctgcct gggtgttgct attattcggt tccagttcca
     4921 gcgcggcgcg caaatcactc accgccgccg ggacattatg acgttggcga taaattgtcg
     4981 cccgcgcaac gtaagcgttg gcagaaggcg caatattgat tgagcgcgtg agatcgttca
     5041 gtgcgagttc cggctgacca ggaatgtaac gttgcgcatg cagccaccag tagagggcat
     5101 tgtttcccag cccacgttgt tctgcctgct gaagccagcg atcgcgagcc gcaccatttc
     5161 ctgccgcctg ggcggtattg gcagcagcaa gcagatcctc attgctcatg tcgtgaagac
     5221 tgattttctg ccaggccgcc agtgcggtgg cgtagtcctc aacctgatac gcctgatagg
     5281 ctaccgcacg atgttgccag gcgttcggtt gtcgttgttc ggcctgaagc catgcataca
     5341 acgccacacc gggtagcgtg tcccgataac actttgccag acggttccag gcggcggcat
     5401 cgtaggaagg cgacatatcg cccagcaagc gaactattgc cgggcaatta tctgcaatac
     5461 ccggcaactg actttgccac tgacgttgct ccgccagcgg taaaggtttc gataaaatcg
     5521 ccaccttcgc cggcgttgcc aggtaaggat gactttccag cagagacgcc agtcgcgcca
     5581 ttaacgtctg gctgacacgc gcatcgccct ggaaaggata gcgttgcagc aataaatcgg
     5641 cagcttcgcg tgactgctcg ttctgcatca gttgccaggt cagttgatcc aggcgggtaa
     5701 gatttgccgg ttcttgctga tacagcaatc gtgccagacg cagagcttca gccttgttat
     5761 gggtcgctac gctaacggta taacgctcct caagcatttc attggcgggg agggtggcga
     5821 gcagtttttg cgctgcgtcg tactgacctt cttttaacag caccggtagc gtcgcgccaa
     5881 caacatactg gcggttatcg gcaaactgta ccgtataatt cgccaacgcc tgaacggggt
     5941 tgacgctgta tttagataac agatagagcc aacttttctc ttgtgcgtcc gtggtaaaca
     6001 gcggcttatt ttcaatgaga taatgctgga ggcgcgcttt ttcgccacga taagccagcg
     6061 cggtcgcgta agtaatatat gactgaggat cggtgaagat cccctgtgat tgcagcgcca
     6121 ggatccgatc atccagctgc gcggcaagaa gcacgtcaaa ccactgacgg cgttctgccg
     6181 cgcttaatgt gttctgctgg cgtgcttcat tatatagcgt atctgcctgg gaccattgtt
     6241 tcaggtagat tgcgcgttgc agcagatcgg ttcgcaacgt ttttccttcc ggcgatgcag
     6301 caaacgtcgc atcgtttagt tgcgctctgg cgacaggtaa ttgtgccagc cgcagggcat
     6361 tctgcccgac ttcactgcga caacgcaggg tcggcgcagc gtcgcacgct ttttgctggg
     6421 caagcagttc ttcaacagtc gtaacgcttt tcacttcaac tggaatagcc gccagactgc
     6481 gctcaagtcg ggcatctcct gggtgacgtt tcagttgatc ctcaagcaac agccgcgccc
     6541 ggtcatcatg accaaaatgg cgataggctt ccgcaaggta taaagtcagc ggaatattat
     6601 ccggcacctg ctggtgtata tattcaaatt cgcggatggc ggttgcttcg tcgttatttt
     6661 tctgtgcctt cagcgccttg tcgagacggg gataaataac gaaatggcga taatcgctca
     6721 gccccagctc ttctgcgctg gtgccgatat tgtctgcgag tgcgctggta ctcaataaag
     6781 acgtcagcag taaaccagac catccgatga cgcgattaag gttattctcc ttcattttcg
     6841 gactccagtt gcgcaacctt ttctgtgttt aaacctgctt tgagtaatag tgattgcatc
     6901 gaaacttgta attcgcgttg aattgtcaga acgcgatcca acgtttcctg gctgataacg
     6961 ccttcggtga ccaaaaactt gccgagcggc agagaactgc gttcatggtg caataacaac
     7021 acgttaattg ctgaacgatt aatatgaccg agcgtggtca gtatttcggc gaacaggaac
     7081 tgatgcggca catattgccg ccagatttca ccggcctgct gttccgtgag ccactgatgc
     7141 tgaaccgcat tgtacaacat tgcccgcgga tcgtgaccgc gtcggcgcgc ataccagtgg
     7201 cgtaaccccg tgacaatttg tccccgcaga acaatgacgt aacgcacttt gcgtccgact
     7261 ttacgcgtca gggccgccag cgaaaccggg tcaataccat cttcactgcc gacaattaac
     7321 tcatcatttt ccagacgcag cggcagcact gcataatgca gcgccacgga ggccggcatc
     7381 tcggcaatca gtgatgaagg gatctgccag gcgtcgatcg actcccacgc cacgccgttt
     7441 tgctctgcca gcgcctgtgc cagctgctcg gcgctaatca gcccctgcat cagcattgaa
     7501 ccgccaaggc gtagaccttc gacgcgatta cgcagtgctg tatcgagttg ttcttcagtg
     7561 atgacctgat tttccagcag aatttgacct aacgggcgca acgagcgggt atcgccagtc
     7621 acgctgggga agtcatgcgt tgttttatcc cacgccacgc gacgtggatc gccgtgttga
     7681 agtacctgtt ttaacgcgcg ccagttggcc atgaagttaa tcaggttgcc ccagaaaaga
     7741 cgcaggacag atagtagccc ctgcgtcagg ccgtagtagc cagtgacgaa aatcacccgc
     7801 tgcacgatgc ggttaaccat caagccaaag tttagccaca gcagggtcat taaccatgcg
     7861 ctgccgctga aaatagaaag gaaatgccag gcatcgggcc acaaactttc atacgccagt
     7921 aacagcaaaa gctggatcat caccagcatc gcgaggaagc tgacaaagtt actgattgcc
     7981 cctttgcggt cgcgccagag aaagtagttc agcgtcaggc tggaggtcca tttgtgggtt
     8041 ttaaagccct ggaaaacaat gccgatgatc cagcgagatt tttgtcgaac cgccgtcgaa
     8101 aaggtatcgg ggaaatattc gcgcacgcag atcatgtttg acgtccgcgc gtgctgtaaa
     8161 aatttacgct gctcgcgttc tttggcttcg tccaccaccg gaaaacggac aaaaatttcc
     8221 gtcatacctt tttctttcag gcggaaacca atgtcgtaat cttcagtaag actctgcacg
     8281 tcgaaagcaa taccgtcacc gtcagctaac agtgcggtca cggcgcggcg gctgaaacaa
     8341 gtaccgacac ctgcgctggg cacctgtccg gcgagggctt cacgcaccgg aacatctttg
     8401 ccatgcagtt ctgaaaactc atcaatgtaa gtcatgctgg tgaagtgcgt ccattcgcgt
     8461 tcgaatgggt ataccgggat ctgaatcaga tctttacgct cgaccagata gttgaacaga
     8521 cgcaattcca tcggtgaaat tacgtcttcg gcgtcatgca gaataaaacc agcaaaagcg
     8581 aaattggcgc tacgctcaaa ctgggtgatg gcgtccagca cgttgttcag gcagtcggct
     8641 ttgctggtgg ggccaggacg cgcgcagact accttatgca cgtttgggaa gcgagcgcac
     8701 acttcgtcaa catcacgctg agtatcgggg tcgttggggt aggtgccaac aaagatatga
     8761 tagttttcat agtcgagcgt ggtcgccgcc agctcggcca tattgccgat gacgcccgtt
     8821 tcattccacg ccggaaccat aatcgctaac ggtttttcat ctggtttata cagttcgcgg
     8881 taactcattc gcgggtagcg gcgataaaca ctcaacttgc gtttaatgcg gcgtacccag
     8941 tagacgacat caataaaaaa atcgtccagc ccgctgatga acatgatgac cgctaacgtt
     9001 atcgcgatta cttttaagcc atatagccag gttgcaaaaa catcaagaag ccagtccaca
     9061 caaaaacctt acattaacgc tggttatgtt tagggtggcg tatattaaag ttttttatga
     9121 attgtgacag ctttttatca ttaataggta ggattattgc ggcacgttat ttttacactg
     9181 gttataaaag ttgccgattg cgtagaatgt agacaaaagc gtggtgtcaa ggaggggagg
     9241 gtaacgcagg gaaagattac gaaagcccgc tccccgcaag gactgacg
//
LOCUS       DADXDL010000135         9278 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.135, whole genome shotgun sequence.
ACCESSION   DADXDL010000135 DADXDL010000000
VERSION     DADXDL010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 9278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9278
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.135"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..576
                     /locus_tag="IRB70_004402"
     CDS             <1..576
                     /locus_tag="IRB70_004402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SopA family protein"
                     /protein_id="HBC0634240.1"
                     /translation="SYIHPDEDNKFDNFMRQHRFSKVNFDTQQTIDFINRFNMNKGLI
                     DQNNNFFIQLIDQALRSTDDTIKANAWHLYKEWIRSDDVSPLFIEIEDNLRTFNTNEL
                     TRNDNIFILFSSVDDGPVMVVSSQRLHDMLNPTKDTNWNSTYIYKSRHEMLPVNLTPE
                     TLFGSKSQDKHALFPIFTASWRANRIKNKGI"
     gene            799..1296
                     /gene="ubiC"
                     /locus_tag="IRB70_004403"
     CDS             799..1296
                     /gene="ubiC"
                     /locus_tag="IRB70_004403"
                     /EC_number="4.1.3.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709881.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate lyase"
                     /protein_id="HBC0634241.1"
                     /translation="MSHPALTQLRALRYFTEIPALDPQLLDWLLLEDSMTKRFEQQGK
                     TVSVTMIREGFVEQNEIPEELPLLPKESRYWLREILLCADGEPWLAGRTVVPVSTLSG
                     PELALQKLGKTPLGRYLFTSSTLTRDFIEIGRDAGLWGRRSRLRLSGKPLLLTELFLP
                     ASPLY"
     gene            1309..2181
                     /gene="ubiA"
                     /locus_tag="IRB70_004404"
     CDS             1309..2181
                     /gene="ubiA"
                     /locus_tag="IRB70_004404"
                     /EC_number="2.5.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxybenzoate octaprenyltransferase"
                     /protein_id="HBC0634242.1"
                     /translation="MEWSLTQNKLLAFHRLMRTDKPIGALLLLWPTLWALWVATPGVP
                     QLWILAVFVAGVWLMRAAGCVVNDYADRKFDGHVKRTANRPLPSGAVTEKEARALFVV
                     LVLISFLLVLTLNTMTILLSIAALALAWVYPFMKRYTHLPQVVLGAAFGWSIPMAFAA
                     VSESVPLSCWLMFLANILWAVAYDTQYAMVDRDDDVKIGIKSTAILFGQYDKLIIGIL
                     QIGVLALMAIIGELNGLGWGYYWSILVAGALFVYQQKLIANREREACFKAFMNNNYVG
                     LVLFLGLAMSYWHF"
     gene            complement(2336..4759)
                     /gene="plsB"
                     /locus_tag="IRB70_004405"
     CDS             complement(2336..4759)
                     /gene="plsB"
                     /locus_tag="IRB70_004405"
                     /EC_number="2.3.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418465.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsB"
                     /protein_id="HBC0634243.1"
                     /translation="MSGWPRIYYKLLNLPLSILVKSKSIPADPAPELGLDTSRPIMYV
                     LPYNSKADLLTLRAQCLAHDLPDPLEPLEIDGTLLPRYVFIHGGPRVFTYYTPKEESI
                     KLFHDYLDLHRSNPNLDVQMVPVSVMFGRAPGREKGEVNPPLRMLNGVQKFFAVLWLG
                     RDSFVRFSPSVSLRRMADEHGTDKTIAQKLARVARMHFARQRLAAVGPRLPARQDLFN
                     KLLASRAIAKAVEDEARSKKISHEKAQQNAIALMEEIAANFSYEMIRLTDRILGFTWN
                     RLYQGINVHNAERVRQLAHDGHELVYVPCHRSHMDYLLLSYVLYHQGLVPPHIAAGIN
                     LNFWPAGPIFRRLGAFFIRRTFKGNKLYSTVFREYLGELFSRGYSVEYFVEGGRSRTG
                     RLLDPKTGTLSMTIQAMLRGGTRPITLIPIYIGYEHVMEVGTYAKELRGATKEKESLP
                     QMLRGLSKLRNLGQGYVNFGEPMPLMTYLNQHVPDWRESIDPIEAVRPAWLTPTVNNI
                     AADLMVRINNAGAANAMNLCCTALLASRQRSLTREQLTEQLNCYLDLMRNVPYSTDST
                     VPSASASELIDHALQMNKFEVEKDTIGDIIILPREQAVLMTYYRNNIAHMLVLPSLMA
                     AIVTQHRHISRDVLMEHVNVLYPMLKAELFLRWDRDELPDVIDALANEMQRQGLITLQ
                     DDELHINPAHSRTLQLLAAGARETLQRYAITFWLLSANPSINRGTLEKESRTVAQRLS
                     VLHGINAPEFFDKAVFSSLVLTLRDEGYISDSGDAEPAETMKVYQLLAELITSDVRLT
                     IESATQGEG"
     gene            4930..5298
                     /gene="dgkA"
                     /locus_tag="IRB70_004406"
     CDS             4930..5298
                     /gene="dgkA"
                     /locus_tag="IRB70_004406"
                     /EC_number="2.7.1.107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBC0634244.1"
                     /translation="MANNTTGFTRIIKAAGYSWKGLRAAWINEAAFRQEGVAVLLAVV
                     IACWLDVDAITRVLLISSVMLVMIVEILNSAIEAVVDRIGSEYHELSGRAKDMGSAAV
                     LIAIIVAVITWCILLWSHFG"
     gene            5408..6016
                     /gene="lexA"
                     /locus_tag="IRB70_004407"
     CDS             5408..6016
                     /gene="lexA"
                     /locus_tag="IRB70_004407"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000646075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repressor LexA"
                     /protein_id="HBC0634245.1"
                     /translation="MKALTARQQEVFDLIRDHISQTGMPPTRAEIAQRLGFRSPNAAE
                     EHLKALARKGVIEIVSGASRGIRLLQEEEEGLPLVGRVAAGEPLLAQQHIEGHYQVDP
                     SLFKPNADFLLRVSGMSMKDIGIMDGDLLAVHKTQDVRNGQVVVARIDDEVTVKRLKK
                     QGNKVELLPENSEFKPIVVDLRQQSFTIEGLAVGVIRNGDWL"
     gene            6089..7414
                     /gene="dinF"
                     /locus_tag="IRB70_004408"
     CDS             6089..7414
                     /gene="dinF"
                     /locus_tag="IRB70_004408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313054.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter DinF"
                     /protein_id="HBC0634246.1"
                     /translation="MAFLTSSDKALWHLALPMIFSNITVPLLGLVDTAVIGHLDSPVY
                     LGGVAVGATATSFLFMLLLFLRMSTTGLTAQAYGAKNPQALARALVQPLLLALGAGAL
                     IALLRTPIIDLALHIVGGSEAVLEQARRFLEIRWLSAPASLANLVLLGWLLGVQYARA
                     PVILLVVGNILNIVLDVWLVMGLHMNVQGAALATVIAEYATLLMGLLMVRKILKLRGI
                     SGEMLKTAWRGNFRHLLALNRDIMLRSLLLQLCFGAITVLGARLGSDIIAVNAVLMTL
                     LTFTAYALDGFAYAVEAHSGQAYGARDGSQLLDVWRAACRQSGIVALLFSVVYLLAGE
                     HIIALLTSLTQIQQLADRYLIWQVILPLVGVWCYLLDGMFIGATRAAEMRNSMAVAAA
                     GFALTLLTLPWLGNHGLWLALTVFLALRGLSLAAIWRRHWRNGTWFAAT"
     gene            7530..7739
                     /locus_tag="IRB70_004409"
     CDS             7530..7739
                     /locus_tag="IRB70_004409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBC0634247.1"
                     /translation="MNKDEAGGNWKQFKGKVKEQWGKLTDDDMTIIEGKRDQLVGKIQ
                     ERYGYQKDQAEKEVDSWEKRHDYRW"
     gene            complement(7781..8296)
                     /gene="zur"
                     /locus_tag="IRB70_004410"
     CDS             complement(7781..8296)
                     /gene="zur"
                     /locus_tag="IRB70_004410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418470.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc uptake transcriptional repressor Zur"
                     /protein_id="HBC0634248.1"
                     /translation="MEKTTTQELLAQAEKICAQRNVRLTPQRLEVLRLMSLQDGAISA
                     YDLLDLLREAEPQAKPPTVYRALDFLLEQGFVHKVESTNSYVLCHLFDQPTHTSAMFI
                     CDRCGAVKEECAEGVEDIMHTLAAKMGFALRHNVIEAHGLCAACVEVEACRHPEQCQH
                     DHSVQVKKKSR"
     gene            8614..>9278
                     /locus_tag="IRB70_004411"
     CDS             8614..>9278
                     /locus_tag="IRB70_004411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2713 family protein"
                     /protein_id="HBC0634249.1"
                     /translation="MSGIISSATEFFNNTLHSNQYEIKDASKEKIKDIYNKSVDYATM
                     SNRAAIIAKIDLFIQRITHNLWTASDNNVSLIKRIDALKNWVEECIDQCTNEQLGDRD
                     YISAFVDRAIFHYAMNFVCNPMENSDVTLIDKCTFDVINHNGLPSTIQLFYDKSYCKA
                     PVASLHLKTVSEGFLNLENAYNVKKDTRLKPLASLLLSFSYDSASADIIGAAERVNDD
                     CEN"
BASE COUNT         2237 a         2177 c         2435 g         2429 t
ORIGIN      
        1 agttatatcc atcctgatga agataacaag ttcgataatt ttatgcgtca acatcgattc
       61 agtaaagtga atttcgatac ccaacagacg atcgatttta ttaacagatt taatatgaat
      121 aaagggctga ttgatcaaaa taacaatttt tttatccaac ttatcgatca ggctctacga
      181 tcaacggatg atacgatcaa agcaaatgcc tggcatcttt ataaagagtg gattcgtagt
      241 gatgatgttt cacctttatt tatagaaatt gaagataatt taagaacctt taacacgaat
      301 gaattaacac gaaacgataa tatctttatc ctgttctcct ctgtcgatga tgggccagtt
      361 atggtggtaa gctcccagcg cttacatgat atgttgaatc ctacaaaaga taccaattgg
      421 aattccacgt atatctacaa atccagacat gagatgttgc ctgttaatct tactccggaa
      481 acacttttcg gctccaaatc tcaggataaa catgcgcttt tccccatttt tactgcgagt
      541 tggcgagcta atcgtataaa gaataaaggt atttaagtaa aggaaaacat caccgttcct
      601 ggcatcctgg gcggtgatgc ccctatggtt gacctcgcca gcacgggcat cggcaaagcg
      661 taaggttcaa cagcgtttta ccacttcatg cgattgttgc gtttttgttg cgcattagat
      721 cacttaattt gctttacatc tcccgtaaac acttttctgc gatacaatgc ctttacgtta
      781 tgtaacggag agttcggcat gtcacacccc gcgttaacgc aactgcgtgc gctgcgctat
      841 tttacagaga tccctgctct ggatccgcaa ctgctcgact ggctgttgct ggaagattcc
      901 atgacaaaac gttttgaaca gcagggaaaa acggtaagcg tgacgatgat ccgcgaaggg
      961 tttgtcgagc agaatgaaat ccccgaagaa ctgccgctgc tgccgaaaga gtctcgttac
     1021 tggttacgtg aaattttgtt atgtgccgat ggtgaaccgt ggcttgccgg tcgtaccgtc
     1081 gttcctgtgt caacgttaag cgggccggag ctggcgttac aaaaattggg taaaacgccg
     1141 ttaggacgct atctgttcac atcatcgaca ttaacccggg actttattga gataggccgt
     1201 gatgccggac tgtgggggcg acgttcccgc ctgcgattaa gcggtaaacc gctgttgcta
     1261 acagaactgt ttttaccggc gtcaccgttg tactaagagg aaaaaaatat ggagtggagt
     1321 ctgacgcaga ataagctgct ggcgtttcat cgcttaatgc gtacggataa gccaattggc
     1381 gcgttactgc tgctctggcc aacattatgg gcgttgtggg tggcgacacc gggcgttccc
     1441 cagctctgga tcctggcggt gtttgtcgcg ggtgtctggc tgatgcgcgc tgccggatgt
     1501 gtggtgaatg attatgctga ccgcaagttt gatggtcatg ttaagcgcac ggcgaaccga
     1561 ccacttccca gcggtgcggt aacagagaaa gaggcgcgcg cgctgtttgt agtgctggta
     1621 ctgatttcgt ttttactggt gctgacgctg aatacgatga ccattctatt gtcgattgcc
     1681 gcgctggcgc tggcgtgggt gtacccgttt atgaagcggt atacccatct accgcaagtg
     1741 gtgctgggcg cggcttttgg ctggtcgatt ccaatggctt ttgctgctgt gagtgagtcg
     1801 gtgccattga gttgctggtt aatgttcctc gccaatattc tctgggcggt ggcatacgac
     1861 acgcagtatg cgatggttga ccgtgatgat gatgtgaaga ttggcattaa atccaccgca
     1921 atcctgttcg gccaatacga taaattgatt attggtattt tgcagattgg cgtactggca
     1981 ctgatggcga tcatcggtga gttaaatggc ttaggctggg gatattactg gtcaattctg
     2041 gtggctggcg cgctgtttgt ttatcaacaa aaactgattg ccaaccgcga gcgtgaagcc
     2101 tgctttaaag cgtttatgaa taataactat gttggtctgg tactgttttt agggctggca
     2161 atgagttact ggcatttctg atgatgtaaa aaagccggat gatcatccgg ctttcttctg
     2221 ggctgcctga tgcgctgcgc ttctcaggcc tacacaacag atcgcaattt attgaatttg
     2281 cagatcatgg aaggccggat aaggcgtttg agccgcatcc ggcaattctc actgattacc
     2341 cctcgccctg cgtcgcactc tcaatcgtca aacgcacgtc tgatgtaatc aactccgcca
     2401 gcaactgata aaccttcatc gtttctgccg gttcggcatc gccgctatcg ctgatatacc
     2461 cttcatcacg cagcgtcagc accagcgaac tgaacaccgc tttgtcgaag aactccggcg
     2521 cgttgatacc gtgcagcacg gagagacgtt gcgcgacggt gcggctctct ttttccagcg
     2581 taccgcggtt gatcgacggg ttggcgctca acagccagaa ggtaatggca taacgttgca
     2641 gcgtttcgcg cgcgcctgcg gccagcagct gtagcgtgcg agaatgcgcc gggttgatat
     2701 gcaactcatc atcttgcagg gtaatcagcc cctgacgttg catctcattt gccagcgcat
     2761 caataacgtc tggcaattcg tcgcgatccc agcgcaggaa cagctccgct ttcagcattg
     2821 ggtaaagcac attgacgtgc tccatcaata cgtcgcggga gatgtggcga tgctgagtga
     2881 caattgccgc catcagcgaa ggcagcacca acatatgcgc aatgttgttg cgatagtagg
     2941 tcatcaacac cgcttgctcg cgcggcagaa tgatgatgtc gccgatagtg tctttctcga
     3001 cttcaaactt gttcatttgc agcgcgtgat cgataagctc gctggcgctg gctgaaggaa
     3061 cggtagagtc cgtggagtaa ggtacgttgc gcatcagatc caggtagcag ttgagttgct
     3121 cggttaactg ctcgcgggtg agtgagcgct gacgtgacgc cagtagcgca gtacagcaca
     3181 ggttcatggc gtttgccgcg cctgcgttgt taatgcgtac catcagatcg gcagcaatat
     3241 tattgaccgt cggcgttaac caggccggac gcaccgcttc gatgggatcg atagattcac
     3301 gccagtctgg tacgtgctgg ttaaggtagg tcatcaacgg cattggttca ccgaagttga
     3361 cgtaaccctg accgagatta cgcagcttgc ttaaaccgcg cagcatctgc ggcaggctct
     3421 ctttctcttt cgttgcaccg cgcagttctt tggcgtaagt acccacttcc atgacgtgct
     3481 cataaccgat atagatcgga atcagcgtaa tcggacgcgt gccgccacgc agcatcgcct
     3541 gaatggtcat cgacagcgta ccggttttcg gatccagcaa acgccccgta cgggaacgac
     3601 cgccttccac gaaatactcg acggaataac cacggctgaa cagttcgccg agatactcac
     3661 ggaaaacggt ggaatagagc ttattgcctt taaacgtacg gcgaataaag aacgcaccca
     3721 gacggcggaa aatcggcccg gccggccaga agttcaggtt gatcccggcg gcgatatgcg
     3781 gcggcaccag cccctggtga tacagcacgt aagaaagcag caggtagtcc atgtgactgc
     3841 ggtggcaagg cacatacacc agctcatgac cgtcgtgggc caactggcga acgcgctcgg
     3901 cgttatggac gttgataccc tggtaaaggc ggttccaggt gaagcccaga atgcggtcag
     3961 tcaggcggat catctcgtaa gagaaattcg ccgcaatctc ttccatcagc gcaatcgcgt
     4021 tctgctgcgc tttttcatgg gagatttttt tgctgcgcgc ttcatcttct accgctttgg
     4081 caatggcgcg ggaggcgagc agcttattaa acagatcctg acgagcaggc agacgtgggc
     4141 ctacggcagc cagacgttga cgggcaaagt gcatacgcgc cacgcgcgcc agtttctgag
     4201 cgatagtttt atccgtgccg tgttcatcgg ccatgcggcg cagcgaaact gacggcgaga
     4261 aacgcacaaa actgtcgcga ccgagccaca gtacggcgaa aaatttctgt acgccgttaa
     4321 gcatacgcag cggcgggttt acttcgcctt tttcacgccc cggcgcgcga ccaaacatca
     4381 ccgatactgg caccatctgc acatccagat ttgggttgct acggtgcaaa tcgagatagt
     4441 cgtggaacag cttaatagac tcttctttcg gcgtgtaata ggtgaacaca cgcggcccgc
     4501 cgtgaatgaa cacatagcgc ggcagtagcg tgccgtcgat ttccagcggc tctaacgggt
     4561 caggcaagtc atgtgccaga cactgggcgc gcaacgtcag caagtctgct ttcgagttgt
     4621 acggtaaaac gtacataatt ggacgagagg tatccagccc cagttccggg gcaggatctg
     4681 ccggaataga cttgcttttt accaggatgc ttaatggtaa attcagtaat ttgtagtaaa
     4741 ttcgtggcca gccggacata aacgatgtaa agcctctggt taataatgca aatgcgcggc
     4801 aaggatagca gaaagtcatg ggaaattctg tggtatccgc tcatgtttcg cgcggcgtta
     4861 cgcaaacccg aatcatcgga tttaacggta cactgatatt gacgctcata atgtaaaaag
     4921 gttctttcaa tggccaataa taccactgga ttcacccgaa ttatcaaagc tgctggctat
     4981 tcctggaaag gtttacgcgc tgcatggatc aacgaagcgg cattccgtca ggaaggcgta
     5041 gcggtattgt tggcggtggt catcgcctgc tggctggatg tggacgcgat tacccgcgtg
     5101 ctgcttatca gctccgtgat gctggtgatg attgtggaaa tcctcaatag cgccatcgaa
     5161 gccgtggttg accgaattgg ctctgaatac catgagctat ccggacgcgc taaagatatg
     5221 ggatccgccg cggttctgat tgcgattatc gtcgccgtga ttacctggtg catcctgtta
     5281 tggtcgcatt ttggataacc cttccagatt tcgataaatc tctggtttat tgtgcagttt
     5341 atggttccaa aatcgccttt tgctgtatat actcacagca taactgtata tacacccagg
     5401 gggcggaatg aaagcgttaa cggccaggca acaagaggtg tttgatctca tccgtgatca
     5461 catcagccag acaggtatgc cgccgacgcg tgcggaaatc gcgcagcgtt tggggttccg
     5521 ttccccaaac gcggctgaag aacatctgaa ggcgctggca cgcaaaggcg ttattgaaat
     5581 tgtttccggc gcatcacgcg ggattcgtct gttgcaggaa gaggaagaag ggttgccgct
     5641 ggtaggtcgt gtggctgccg gtgaaccgct tctggcgcaa cagcatattg aaggtcatta
     5701 tcaggtcgat ccttccttat tcaagccgaa tgctgatttc ctgctgcgcg tcagcgggat
     5761 gtcgatgaaa gatatcggca ttatggatgg cgacttgctg gcagtgcata aaactcagga
     5821 tgtacgtaac ggtcaggtcg ttgtcgcacg tattgatgac gaagttaccg ttaagcgcct
     5881 gaaaaaacag ggcaataaag tcgaactgtt gccagaaaat agcgagttta aaccaattgt
     5941 cgttgacctt cgtcagcaga gcttcaccat tgaagggctg gcggttggag ttattcgcaa
     6001 cggcgactgg ctgtaacata tctctgagac cgcgatgccg cctggcgtcg cggtttgttt
     6061 ttcatctctc ttcatcaggc ttgtctgcat ggcattcctc acttcatctg ataaagcact
     6121 ctggcatctc gccttaccca tgattttctc caatatcacc gttccgttgc tgggactggt
     6181 cgatacggcg gtaattggtc atcttgatag tccggtttat ttgggcggcg tggcggttgg
     6241 tgcaacggcg accagctttc tctttatgct gttgctgttt ttacgcatga gcaccaccgg
     6301 gctgactgcg caggcttatg gtgccaaaaa tcctcaggca ttagcccgtg cgctggtgca
     6361 accgttgctg ttggcgttgg gggctggggc gttaattgcg ctgctgcgta cgccgattat
     6421 cgatctggcg ctgcatattg ttggcggcag cgaagcggtg ctagaacagg cgcgacgctt
     6481 tcttgaaatc cgctggttaa gtgcaccggc gtcgctggcg aatctggtat tacttggttg
     6541 gttactcggt gtgcaatatg cccgtgcgcc agtaattttg ttagtggtcg gcaatatcct
     6601 caacattgtg ctggatgtct ggctggtgat ggggctgcat atgaacgtgc agggcgcggc
     6661 gctggcgacg gttattgcgg aatatgcaac attgctgatg ggtctgctaa tggtgcgtaa
     6721 aatcctcaaa ctacgcggaa tctccggcga aatgctgaaa actgcctggc gaggaaactt
     6781 ccgtcacttg ctggcgctta accgcgatat catgctgcgc tcgctgttgc tgcaactctg
     6841 tttcggcgcg atcactgtac ttggcgcgcg actggggagt gacattatcg ctgttaacgc
     6901 ggttctgatg acgctactca cctttaccgc ctatgcgctg gatggttttg cctacgcggt
     6961 tgaagcacat tccggtcagg catacggtgc gcgcgacggt agtcaattgc tggatgtctg
     7021 gcgggcagcg tgccgccagt cggggattgt agcgttactg ttttcggtgg tttatttgct
     7081 ggcaggggaa cacatcattg cgttgctgac gtcgttaacc cagattcagc agctggctga
     7141 ccgctatctt atctggcagg tgattttgcc gttggtcggc gtctggtgtt atctgctcga
     7201 cggcatgttt ataggtgcaa cgcgcgccgc cgaaatgcgt aacagtatgg cggtggccgc
     7261 cgcaggtttt gcgctgacgc tccttacgct gccgtggctg gggaatcatg gtttgtggct
     7321 ggcattaacc gtctttctgg cgttacgcgg gctttctctg gcggctatct ggcggcgtca
     7381 ctggcgcaac ggtacctggt ttgccgcaac gtgacggtta aaaattctga ataaataatc
     7441 ctaagccaaa ttgctgacta cacttaatct cacgttcaga agaaaagtga acgtactctc
     7501 attcacaacc taacgatgag gtcttgatta tgaataaaga tgaagccggc ggtaactgga
     7561 aacagtttaa aggtaaagtg aaagagcaat ggggcaaact gaccgatgat gatatgacga
     7621 tcattgaagg taaacgtgat caactggtcg gtaaaatcca ggaacgctac ggttatcaga
     7681 aagatcaggc agaaaaagag gttgatagtt gggaaaaacg ccatgattac cgctggtaat
     7741 taatccctcc tgcccgacgt gtacaaggat gtacgccctc ttaacgtgat ttctttttca
     7801 cctgtacaga gtgatcatgc tggcactgtt caggatgacg acacgcttcc acttccacgc
     7861 atgccgcaca gagtccatgt gcttcaatca cattatgccg cagggcaaac cccatttttg
     7921 ccgccagcgt atgcataatg tcttccacgc cttctgcaca ttcttctttc actgcgccgc
     7981 agcgatcgca aataaacatg gctgacgtat gcgtgggctg gtcgaacaga tgacagagca
     8041 cataactgtt ggtggattcc accttatgca caaaaccttg ctcaagcaga aaatccagcg
     8101 cgcgataaac cgttggcggc ttggcttgcg gttcagcttc gcgcagcaaa tcaagcagat
     8161 cataagcgct gatagcgcca tcctgcagac tcatcaggcg caacacttcc aggcgctgtg
     8221 gggtcaggcg cacattacgc tgcgcgcaga ttttttcagc ctgcgctaat aactcctgcg
     8281 ttgtggtctt ttccatcggg cacctcaaag tgggggttaa gaatgtcctt actttaccat
     8341 gttccaggaa aaacaccgag aacccttatt gttgccgtaa tgttgatttt ctgttttgta
     8401 cgtaaggtgt tgtgttgcct ggtcgtacca ttatcaacac gataataatt aatacttcat
     8461 ttttaaataa attgctttaa gttaactcgc tatttattta actggggttg atcgcatacc
     8521 tgtacttcag aaattatgag cgatttttga tagtgagcag atggcaaaag aattataagg
     8581 aggacacggt acgacaaaaa aggtgcgtat atcatgtcag gtataatttc aagtgcaaca
     8641 gaattcttca ataatacact ccattcaaat caatacgaaa ttaaagatgc gagcaaagaa
     8701 aaaataaagg atatatataa taaatcggtt gattatgcaa cgatgagtaa tcgcgctgcg
     8761 attattgcaa aaatagattt gtttattcag agaatcaccc ataatttatg gactgcaagt
     8821 gataataatg tttccttaat taagcgaata gatgctctca aaaattgggt tgaggagtgt
     8881 attgatcagt gcactaatga gcaattaggt gatcgtgact atatttctgc atttgtggat
     8941 cgggcgattt ttcattacgc gatgaatttt gtttgtaatc caatggaaaa tagcgatgta
     9001 actctaatag acaagtgtac tttcgacgta ataaatcata atggccttcc ctccacgatt
     9061 cagctatttt atgataaatc ctattgtaaa gcacctgtag cgtcattaca tctaaaaaca
     9121 gtaagcgaag gctttttaaa tttggaaaat gcatataatg taaagaaaga tactcgctta
     9181 aaacccctgg cctccctttt actttcattt tcatatgata gtgcatcagc agatatcata
     9241 ggagcagcag agagagttaa tgatgattgt gaaaacta
//
LOCUS       DADXDL010000136         8735 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.136, whole genome shotgun sequence.
ACCESSION   DADXDL010000136 DADXDL010000000
VERSION     DADXDL010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8735
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.136"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            55..1941
                     /locus_tag="IRB70_004412"
     CDS             55..1941
                     /locus_tag="IRB70_004412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012132915.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FTR1 family iron permease"
                     /protein_id="HBC0634250.1"
                     /translation="MSVWASTNYAPLIEDIEQRLDKTAELYQQQHADEARRTVQMAYF
                     EVFENLEGPIRINISARKSYEMESAFGEIRRMIGEKKPLADVQARIDWLKAALREVEP
                     VLDGGHRLVAEEQHNALSRDDIAVHWQESFRTIDDLLAQAVTEYQAGNYSVASQHVQQ
                     AHYQGFKNSEMEMSLRQNRSAKDAASINQQFSSLIALTAQPDHLNDVSYQVTTLLQDI
                     EDILPGLPTTRDDQQVAAAQSADNIPAADEGNNRTDWAEVTTGINQSIQDAIARYQGG
                     DAKNAILDIQDTYFDRFEASGMENKIGSRDSAFKTTLEAYFTRLVSLMKAGQPVERLN
                     AEASALTQDLQKAVTMLGEGEETQWSLLLYSLMIIVREGLEALLIVAAIVAYMVKNNH
                     QDKLPLIRQSVIVALIASVITAAIFQMLFTNSGASRELLEGITMLIAVVMLFFMSYWL
                     LSKVEARHWKAWLEGKLSHSLSRGSLVGLWLTSFLAVYREGAETVLFYYALIGDANTV
                     SGHMAIGAGFVIGCVVLLLAWLVMRYSVVRLPLKPFFMFTGSFMYLMAFVFAGKGVLE
                     LVEGKLFQPTLINGFPEISWLGIYPYVETLLPQVVLLLAALVALWVMRRKSAVPGETI
                     KNNP"
     gene            1982..2509
                     /locus_tag="IRB70_004413"
     CDS             1982..2509
                     /locus_tag="IRB70_004413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016674077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron transporter"
                     /protein_id="HBC0634251.1"
                     /translation="MTMKKTLIASAVMASIFIAPAAFAFKEYPAGEPVTMNEMELAAV
                     YLQPIDMEPRGMGLPAAKADVHLEADIHAVEGNKNGFGAGEWIPYLTISYTLVNNDTG
                     EKQEGTFMPMVASDGPHYGANIKMMGVGNYKVTYHIEPPSKAGMHRHTDSETGVGRWW
                     KPFDVSYEFKYVGLN"
     gene            2613..3992
                     /locus_tag="IRB70_004414"
     CDS             2613..3992
                     /locus_tag="IRB70_004414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003836820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2318 domain-containing protein"
                     /protein_id="HBC0634252.1"
                     /translation="MSYFFVTTLQVFFCIALLSGVLWSRNDPPSLRPLTWTLLTGLIA
                     GVLAGLFIHGSQPVQLLLVGAEVMVSLLFVLSFWWASTRIRYLWQGILIFGAARHWAL
                     DPNLGGLTSTHVLNTDLLLNLTAVVLAFAILCLAGVLCAMLLRRIRGLYWPLTLILLV
                     MIWLPLSGNLLLLLMKLQVVPLGKSLLSFVAKVTNNTALYNWAGAALLLALALCWLPA
                     LLRAFRQTRETEEPIAHRLALAQRRNALRLWLVTIGCAVVVIAGQLWWDKVASQPPQL
                     SEAVPVTLGSDGMVRLPVEQLRDGKLHRFVWVADDGKAVRFFVINRYPDKLRFGVVFD
                     ACLLCGDQGYVMEGNQVICVACGVHIFIPSIGKAGGCNPVPIENWHNDEKELVIPGKE
                     LATGVNYFSTVMTIKVTDPVDGSTLTNTSADYKYSYGGKTWFFSSEANYERFRETPEQ
                     FVPADMREE"
     gene            3995..5278
                     /locus_tag="IRB70_004415"
     CDS             3995..5278
                     /locus_tag="IRB70_004415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011906231.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0634253.1"
                     /translation="MLWRMLRQSWGRNLRRKVLAIITVFLASSLISALLAVSIDIGDK
                     MSRELKSYGANILIEPAGQAALPALFSESSNPLSGQDFLDEAELPNIKDIFWRNNIVG
                     FAPMLGGEASVEGEPVRILGTFFSQPVDIPDEEGYETGQKTVSPYWQVTGDWPQEPAG
                     AEPQTLVGHALARQMGWKPGDKLTLRTEGEAVQVTVSGILSSGGDEDNQLVMPLSTVQ
                     HLLGLPGKVQAIRVSALTVPENELSRRARENLDALNAEEYDLWYCTAYVSSIAHQLEE
                     AISGAEVRPVWQVAASEGVVIDKIQLLMAVVTVAALVASAMGIASLMTSTIMERAKEI
                     GLMKALGARQWQIMLLFYLEAASSGLAGGALGCIAGWGLAKAIGVMLFDAPLNFAWIV
                     VPCVLVIAVLIALIGTWFPARRIARLYPVEVLYGR"
     gene            5268..6398
                     /locus_tag="IRB70_004416"
     CDS             5268..6398
                     /locus_tag="IRB70_004416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000729219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBC0634254.1"
                     /translation="MAAKRTMLWLLVWRALRLRFQRVSVVFAALMVGATIVTALSAVW
                     FDINTKMSEELRTFGANFYIGPGHGSSMPQQELQSILDQAPQGLVHGASPWLYGMART
                     ELEKVVMVGVWFESLQKMVPYWQVTGSWIGVSFDDRNAMIGVKLAERLNVQPGDSITL
                     VDHNQRKNLQIKGIVESGDATDNMLIVSLDVAQAWLHQPGKISHGLLSVSNDVGQVEN
                     YASRLQAQYPDLEIRPVRKVSASEGQVLDKIKGLMGLVSIVILALSSLCVNTTLMAIV
                     GERAREFALQKALGSSNGDIVRQILLETSIIALAAVACGWVLGYLLAQLLGLTVFNAA
                     ISLRLPVLPITLVLSLLVAILAAIVPVRRAVSVEPAKVLKGE"
     gene            6403..7098
                     /locus_tag="IRB70_004417"
     CDS             6403..7098
                     /locus_tag="IRB70_004417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004863043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0634255.1"
                     /translation="MSVTHIPQVAIETRHLYKRFGDVTALDDINLRIAQGEFVAIMGA
                     SGSGKTTLMNILTCLDTATEGQVFLDGTDAAALDEEGRRRFRAEKIGLVFQQFHLIPF
                     LTALENIMLAQHYHSVVDEAAARKVLEQVGLGHRVTHLPSQLSGGEQQRVCIARALVN
                     EPPVIFADEPTGNLDEENEQRVLDLLTDLHRQGRTIVMVTHNPALGQFADRILRLQHG
                     KYLGEEANQHALA"
     gene            7085..7570
                     /locus_tag="IRB70_004418"
     CDS             7085..7570
                     /locus_tag="IRB70_004418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBC0634256.1"
                     /translation="MRWHNVLLLAAAILISGCKEEKLAVGAPAPALAVFDLQGQESGL
                     ERWQGKAVYLNFWSAGCGGCLAEMDTLEALSKKWGDKVVVVAVNTDPETVRINDLLAK
                     HQITYPVVRDQLNITQERYQVIGTPTSVLIDSEGRVLELHQGMRKPPELEATFARLAA
                     R"
     gene            7595..8080
                     /locus_tag="IRB70_004419"
     CDS             7595..8080
                     /locus_tag="IRB70_004419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005122128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634257.1"
                     /translation="MAFIWNDESLAILRENAGILTTEQIAQLLHTNITAVRNMAYRLK
                     LSLRVTAYNHRRIAQVQALYASETLSLKEIAAKTGLTASTVQYIVYVKSKNKPYATTE
                     YVSFETENAVHYRVQKEFVDTERSLLDNISDNTRFRELYLTDGTFYCARNIKYEVFIS
                     E"
     gene            8202..>8735
                     /locus_tag="IRB70_004420"
     CDS             8202..>8735
                     /locus_tag="IRB70_004420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine-type phosphatase"
                     /protein_id="HBC0634258.1"
                     /translation="MKKLILAAAVAGAVLLSSAAQAQTTPEGYQLQQVLMMSRHNLRA
                     PLANNGSVLEQSTPNQWSEWDVPGGQLTTKGGVLEIYMGHYMREWLAELGMVTSGECP
                     TPDTVYTYANSLQRTVATAQFFITGAFPGCDIPVHHQEKMGTMDPTFNPVITDDSAAF
                     SQKAVQAMEKERSQMQLD"
BASE COUNT         1865 a         2234 c         2693 g         1943 t
ORIGIN      
        1 gtgcgtaact tccgtaactc tttgttggtt actctctttg gcttgtttat aagcatgagt
       61 gtctgggcgt cgacgaatta tgcgcctttg attgaagata tcgagcaacg tcttgataaa
      121 acagcggaac tttatcagca acagcatgcc gacgaggcgc gccgcacggt acaaatggcc
      181 tattttgagg tgttcgagaa cctggaaggg ccgatccgca tcaacatttc cgcgcgcaaa
      241 agttacgaga tggagagcgc attcggcgag atccgtcgaa tgattggcga gaaaaaaccg
      301 ctcgctgacg tccaggcgcg cattgactgg ctgaaagccg cactgcgcga agtggaaccg
      361 gtgctggatg gcggacatcg tctggtggcc gaagagcagc acaacgcgct gtccagggac
      421 gacattgccg ttcactggca ggagagtttc aggacgatcg acgatctgct ggcgcaggcg
      481 gtcactgaat atcaggccgg gaattacagc gttgccagtc agcacgttca acaggcgcac
      541 tatcagggct ttaaaaactc tgagatggag atgtccctca gacaaaaccg ttctgcaaaa
      601 gatgccgcct ccattaacca acaattctca tccctgattg cgctgaccgc gcaacctgac
      661 catctcaacg atgtctccta tcaggtcact acgctgctac aggatatcga ggatatctta
      721 cccggcttgc caaccacccg tgacgatcag caggttgccg cagcgcaaag cgcagacaac
      781 attccggcgg cggacgaggg aaataaccgc accgactggg ctgaggtgac gacgggaatt
      841 aaccagagca ttcaggacgc gatagcgcgc tatcagggcg gcgatgcgaa gaatgcgatt
      901 ctggatatcc aggataccta cttcgaccgc ttcgaagcca gcggcatgga aaacaaaatc
      961 ggctctcgcg attcggcatt taaaaccacg ctggaggcgt attttacccg cctggtcagt
     1021 ctgatgaagg ccggtcagcc ggttgagcgc ctgaatgcag aggccagcgc gctgacgcag
     1081 gatctgcaaa aagccgtgac gatgctgggc gaaggcgaag aaacccagtg gagtctgctg
     1141 ctctatagtc tgatgatcat cgtgcgcgag gggctggaag cgctgctgat tgttgcggca
     1201 atcgtggcct acatggtgaa aaacaaccat caggataagc tgccgcttat tcgtcagtcg
     1261 gtaattgtgg cgctgatcgc cagcgtcatc accgccgcta tcttccagat gctgtttact
     1321 aactccggcg ccagccgtga actgctggaa ggcataacga tgctgattgc cgtcgtgatg
     1381 ctgttcttta tgagttactg gctgctgtcc aaagtggaag cgcgccactg gaaagcctgg
     1441 ctggaaggca aactgtctca ttccctgtcg cgaggctccc tggtcggact atggctgacc
     1501 agcttcctgg cggtgtaccg cgaaggggcg gaaacggtgc tgttctatta cgctctgatt
     1561 ggcgatgcaa acacggtatc cggccatatg gcgattggcg ccggttttgt gattggctgc
     1621 gtggtgctgc tgctcgcctg gctggtgatg cgttactcag tggtgcgcct gccgctgaaa
     1681 cccttcttta tgtttaccgg cagtttcatg tatctgatgg ccttcgtctt tgcgggcaaa
     1741 ggcgttctgg aactggtgga aggcaaactg ttccagccta cgttgattaa cggcttccct
     1801 gaaatcagct ggctggggat ttatccctac gtggaaacgt tgttaccgca ggtcgtattg
     1861 ctgctcgcgg cgctggtggc gctgtgggtg atgcggcgca aaagcgcggt tcccggggag
     1921 acgataaaaa ataacccata atcgttgtat agccgttgtt ttagacgaga ggatacgttt
     1981 gatgaccatg aagaaaaccc tgattgccag cgcagtgatg gccagcattt tcattgcgcc
     2041 agccgcgttt gcttttaaag agtacccggc aggcgagcct gtcaccatga atgaaatgga
     2101 gctggcggcc gtttacctgc aaccgattga tatggaaccg cgcggcatgg gcttaccggc
     2161 agcaaaagcc gatgttcacc ttgaagcgga tatccacgct gtagaaggca ataaaaacgg
     2221 ctttggcgca ggggaatgga tcccgtacct gaccatcagc tacaccctgg tcaacaacga
     2281 cacgggcgaa aaacaggaag gcaccttcat gccgatggtt gccagcgatg gcccgcacta
     2341 tggcgcgaac atcaaaatga tgggcgtggg caactataaa gtgacctacc acattgaacc
     2401 gccgtcaaaa gccgggatgc atcgccatac tgacagcgaa acaggcgtag gccgctggtg
     2461 gaaaccgttt gatgtgagct acgagtttaa atatgtcggt ctgaactaaa accgactaac
     2521 caacgcgcca ggaggattcc cccttctggc gcgttggtca gaccgatcat atgcccgtcg
     2581 cttaattcaa cccgccgtac agagtcgaag ttatgagtta ctttttcgtc acgacgctac
     2641 aggtcttttt ctgcattgcg cttctttccg gtgttctctg gagtcgaaac gatcctccct
     2701 ctttacgtcc gctgacctgg acgctgctga ccgggctgat tgccggcgtg ctggcgggac
     2761 tgtttattca cggcagccaa ccggtacaac tgctgctggt tggggcggag gtcatggtat
     2821 cgctgctgtt tgtcctcagt ttctggtggg cttcaacgcg tatccgctat ctgtggcagg
     2881 ggattctgat tttcggcgct gcccgccatt gggcgctgga ccctaatctg ggcgggctga
     2941 ccagtacgca tgtgctgaat actgacctgc tgttaaacct gacggccgtc gttctcgctt
     3001 ttgcgatcct ctgtctggcg ggcgtactct gcgcgatgct gctgcggcgt attcgcggcc
     3061 tgtactggcc gttaacgctg attctgctgg tgatgatctg gctgccgctg agcggcaacc
     3121 tgctgttgtt gctgatgaaa ttacaggttg ttccgctggg aaaatcactg ctgagcttcg
     3181 tggcgaaagt cacaaataac acggcgctgt ataactgggc gggagccgcg ctgctgctgg
     3241 ccctggcgct gtgctggctt ccggcgctgt tgcgggcttt tcgacagacg cgggaaaccg
     3301 aagaaccgat tgctcaccgt ctggcgctgg cgcagcgtcg caacgctttg cggctgtggt
     3361 tggtcacaat cggctgcgcg gtggtcgtta tcgcaggcca actgtggtgg gataaagtgg
     3421 cctcgcagcc gccgcaactc tctgaagccg tgcccgtaac gctggggagc gatggcatgg
     3481 tgcgcctgcc ggttgaacag cttcgtgacg gtaaactgca tcgtttcgtc tgggtggcgg
     3541 acgatggcaa agcggtgcgc ttcttcgtga ttaaccgcta tcccgacaag ctgcgttttg
     3601 gcgtggtgtt cgacgcctgc ctgctgtgcg gcgatcaggg ttatgtcatg gagggcaatc
     3661 aggttatctg cgtcgcctgc ggagtgcata tttttattcc gtctatcggc aaggccggtg
     3721 gctgtaaccc ggtgccgatt gaaaactggc acaatgatga aaaagagctg gtgatccccg
     3781 gtaaagaact ggcgacaggg gtgaactact tctcgacggt catgactatt aaagtgaccg
     3841 atccggtcga tggttcaacg ttgaccaata cctcagccga ttacaaatac agctatggcg
     3901 gcaagacctg gttcttctcg tcagaggcta actatgaacg cttccgtgaa acgccggagc
     3961 agtttgttcc tgccgacatg agggaggaat aatcatgctg tggcggatgt tacgacaatc
     4021 ctgggggcgc aatttacgcc gcaaagtgct ggcgataatc accgtttttc tggcctccag
     4081 cctgatctcg gcgctgctgg cggtgtccat tgatatcggc gacaaaatgt ccagagagct
     4141 gaagtcttat ggtgcgaaca ttttgattga acccgccgga caggctgcgc tgcccgcgct
     4201 gtttagtgag agcagtaatc cgctttccgg tcaggatttt cttgatgaag ccgagctgcc
     4261 gaacatcaaa gatatcttct ggcgaaacaa cattgtcggg tttgcgccga tgctcggcgg
     4321 cgaagccagc gtggagggag aaccagtgcg gattctgggc actttcttca gtcagccagt
     4381 ggatattcct gatgaagagg gatatgagac ggggcagaaa acggtcagcc catactggca
     4441 ggtgaccggc gactggccgc aggaacccgc aggcgcagag ccgcagacct tagtcgggca
     4501 cgcgctggcg cggcaaatgg gctggaaacc cggtgataag ctgacattac gtaccgaagg
     4561 cgaagcagtg caggtcaccg tcagcggtat cctctccagc ggcggcgatg aagataacca
     4621 actggtgatg ccgctaagca cggtacagca cctgctgggg ctccccggaa aagtgcaggc
     4681 gattcgcgtc tcggcgctga cggtgccgga aaacgaactg tcccgccgcg cgcgggaaaa
     4741 cctggacgcg ctcaatgccg aagagtacga cctctggtat tgcacggcct atgtgtcgtc
     4801 gatcgcgcat cagctggaag aggcgatttc cggtgcggaa gtgcgcccgg tatggcaggt
     4861 cgcggcgtcc gaaggggtgg tgatcgataa aattcagttg ctgatggcgg tcgttaccgt
     4921 cgcggcgctg gtggcttccg caatggggat cgcctcgctg atgaccagca ccattatgga
     4981 acgcgccaaa gagatcggtt tgatgaaagc gctgggtgcg cgacagtggc aaattatgct
     5041 gctgttctac ctggaagcgg cgtccagcgg gctggctggc ggtgcgctgg gatgtattgc
     5101 cgggtggggg ctggcgaaag cgattggcgt catgctcttc gacgcgccgc ttaattttgc
     5161 ctggattgtg gtgccgtgcg tactggtgat tgcggtactg attgcgttga tcggcacctg
     5221 gttcccggcc cggcggattg cccggctgta tcctgtggag gtgctgtatg gccgctaaac
     5281 gtaccatgct ctggctgctg gtgtggcggg cgctgcgtct gcgttttcag cgggtcagcg
     5341 tggtgtttgc cgcgctgatg gtgggggcga ccatcgtgac ggcgctttct gccgtctggt
     5401 tcgacattaa caccaaaatg agcgaagaac tgcgcacctt cggcgcgaat ttttacatcg
     5461 ggccggggca cggttccagt atgccgcagc aggagttgca gagcattctc gatcaggcgc
     5521 cgcaggggct ggtgcatggc gccagtccgt ggttgtacgg catggcgcgt accgagctgg
     5581 aaaaagtggt gatggttggc gtgtggttcg agtcgctgca aaaaatggtg ccgtactggc
     5641 aggtcaccgg tagctggatt ggcgtcagtt ttgacgaccg taatgcgatg atcggcgtca
     5701 aactggcgga acgcctcaac gtgcagccgg gcgacagcat cacgctggtg gatcacaatc
     5761 agcgtaagaa tttgcagatt aaaggcattg tggagtctgg cgatgcgacg gacaacatgc
     5821 tgatcgtcag cctcgacgtg gcgcaggcct ggctgcatca gccgggcaaa atcagccacg
     5881 gcttgctgag cgtcagtaac gatgtcggcc aggtggagaa ctatgccagc cggttgcagg
     5941 cgcagtatcc tgacctggag attcgtccgg tgcgtaaggt ctctgcttcc gaagggcagg
     6001 tgctggataa aattaaaggt ctgatgggac tggtctcgat cgtgattctg gcgctctctt
     6061 cgctgtgcgt gaataccacg ctgatggcga ttgtcggcga gcgggcgcgc gagtttgcgc
     6121 tgcaaaaagc gcttggttcc agcaacggcg atatcgtgcg gcaaattctg ctggaaacca
     6181 gcatcatcgc gctggcggcg gtggcgtgcg gctgggtgct gggatatttg ctggcgcaac
     6241 tgttgggatt aacggtgttt aatgccgcca tatcactgcg tctgccggtg ttgcccatta
     6301 ctctggtgtt gtctttactg gtcgccattc tggcggcgat tgttccggtg cgacgcgcgg
     6361 taagcgtcga gcctgctaaa gtgctgaaag gagagtagcg ccatgtccgt tacgcatatc
     6421 cctcaggtgg cgatcgaaac ccgccactta tacaaacggt tcggtgacgt taccgccctg
     6481 gatgacatta atctgcgcat tgcgcagggt gaatttgtcg ccattatggg cgcttctggt
     6541 tctggtaaaa ccacgctgat gaatattctg acgtgccttg atacggcgac ggaagggcag
     6601 gtgtttcttg atggcaccga tgccgccgcg ctggatgaag aggggcgccg tcgctttcgc
     6661 gccgagaaaa tcggcctggt atttcagcag ttccatttga tcccgttctt aactgcgctg
     6721 gaaaacatca tgctcgccca gcattaccac agcgtggtgg atgaagcggc ggcgaggaag
     6781 gtgctggaac aggtagggct tgggcatcgt gtgacgcacc tgccgagcca gctttccggt
     6841 ggtgagcagc agcgtgtgtg tatcgcccgg gcgctggtca acgaaccgcc ggttattttc
     6901 gcggatgaac cgacgggcaa cctggatgaa gagaatgagc agcgggtgct ggatctgctc
     6961 accgatctgc atcgtcaggg gcgcacgatt gtgatggtga cgcacaaccc tgcgcttggg
     7021 cagtttgccg accgtattct gcggctgcaa cacggtaaat atctgggtga ggaggccaat
     7081 caacatgcgc tggcataatg tgctgttact cgcggcggcg atcctgataa gcgggtgtaa
     7141 agaagaaaag ctggcggtcg gggcaccggc cccggcgctg gcggtgtttg atctgcaagg
     7201 ccaggagtca ggccttgaac gctggcaagg aaaggcggtg tacctgaatt tttggtctgc
     7261 gggatgcggg gggtgcctgg cggaaatgga cacgctggaa gcgctgagca aaaaatgggg
     7321 cgataaagtg gtggttgtgg cggtcaatac cgaccctgaa acggtcagga tcaacgatct
     7381 gctggcaaaa catcagataa cctatccggt ggtgcgcgat cagctcaaca ttacccagga
     7441 acgttatcag gtgatcggca cgccgacctc cgtactgatt gactccgaag gacgcgttct
     7501 ggagctacac cagggtatgc gtaagccgcc tgagttagag gccacgtttg cgcgcctggc
     7561 ggcgcgatga acgacgcgta cggagagata cccaatggca tttatctgga acgacgaaag
     7621 ccttgcgatt ctgcgggaaa acgcgggcat cctcacgaca gagcagatag cgcaactgct
     7681 tcacactaat attaccgccg tgcggaatat ggcctatcgg ctgaaactga gccttcgggt
     7741 gacggcgtat aatcaccgac gcatagcgca ggttcaggcg ctttatgcct ctgagacgtt
     7801 gagtctcaaa gagatcgcgg cgaaaacggg gctgacggcc agtaccgtgc aatatatcgt
     7861 gtacgtgaaa tcaaaaaata agccctacgc caccacggaa tatgtctctt ttgaaacgga
     7921 gaacgccgtt cattaccgcg tgcaaaaaga atttgtcgat acggaacgtt ccctgctgga
     7981 caacatctct gataacacgc gatttcgtga actgtatctg acggacggca ctttttattg
     8041 cgcccgcaat attaagtatg aggtttttat ctcggagtaa ccggaacacg ctgacctgcc
     8101 ggttatcttc tggaatctcc cgttttgcga aaccgttccc ggaaaaatgt catatttctg
     8161 tcacactcta tgaggattga taacaacaag aggttgtagg gatgaaaaaa ttgatactcg
     8221 ccgccgctgt ggcaggggct gttttattgt cgtccgccgc gcaagcgcag acaacgccgg
     8281 aaggttatca actgcaacaa gtgttgatga tgagccgaca caacttgcgc gcgccgttgg
     8341 ccaataatgg cagcgtgctg gagcagtcca cgccgaatca gtggtcggag tgggatgtgc
     8401 ccggcgggca gctcaccacg aaaggcggtg tgctggaaat ttatatgggc cactacatgc
     8461 gagaatggct ggcggagctg gggatggtca cgtcaggcga atgcccgacg ccggacacgg
     8521 tatataccta tgccaacagt ctgcaacgca ccgttgcgac ggcacaattc tttatcaccg
     8581 gcgctttccc tgggtgcgac attccggtac atcatcagga aaaaatgggc acgatggacc
     8641 caacgtttaa tccggtgatc accgatgact ctgcggcgtt tagccagaaa gcggtgcagg
     8701 cgatggaaaa agagcgcagc cagatgcagc ttgac
//
LOCUS       DADXDL010000137         8713 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.137, whole genome shotgun sequence.
ACCESSION   DADXDL010000137 DADXDL010000000
VERSION     DADXDL010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8713)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8713)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8713
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.137"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(309..572)
                     /gene="rpsT"
                     /locus_tag="IRB70_004421"
     CDS             complement(309..572)
                     /gene="rpsT"
                     /locus_tag="IRB70_004421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006117633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBC0634259.1"
                     /translation="MANIKSAKKRAIQSEKARKHNASRRSMMRTFIKKVYAAIEAGDK
                     AAAQKAFNEMQPIVDRQAAKGLIHKNKAARHKANLTAQINKLA"
     gene            675..893
                     /locus_tag="IRB70_004422"
     CDS             675..893
                     /locus_tag="IRB70_004422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2575 family protein"
                     /protein_id="HBC0634260.1"
                     /translation="MCRHSLRSDGAGFYQLAGCEYSFSAIKIAAGGHFLPVICAMAMK
                     SHFFLISVLNRRLTLTAVQGILGRFSLF"
     gene            901..1842
                     /gene="ribF"
                     /locus_tag="IRB70_004423"
     CDS             901..1842
                     /gene="ribF"
                     /locus_tag="IRB70_004423"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional riboflavin kinase/FAD synthetase"
                     /protein_id="HBC0634261.1"
                     /translation="MKLIRGIHNLSQAPQEGCVLTIGNFDGVHRGHRALLQGLQEEGR
                     KRNLPVMVMLFEPQPLELFATDKAPARLTRLREKLRYLAECGVDYVLCVRFDRRFAAL
                     TAQNFISDLLVKHLRVKFLAVGDDFRFGAGREGDFLLLQKAGMEYGFDITSTQTFCEG
                     GVRISSTAVRQALADDNLALAESLLGHPFAISGRVVHGDELGRTIGFPTANVPLRRQV
                     SPVKGVYAVEVLGLGEKPLPGVANIGTRPTVAGIRQQLEVHLLDVAMDLYGRHIQVVL
                     RKKIRNEQRFASLDELKAQIARDELTAREFFGLTKPA"
     gene            1885..4701
                     /gene="ileS"
                     /locus_tag="IRB70_004424"
     CDS             1885..4701
                     /gene="ileS"
                     /locus_tag="IRB70_004424"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBC0634262.1"
                     /translation="MSDYKSTLNLPETGFPMRGDLAKREPGMLARWTDDDLYGIIRAA
                     KKGKKTFILHDGPPYANGSIHIGHSVNKILKDIIVKSKGLSGYDSPYVPGWDCHGLPI
                     ELKVEQEYGKPGEKFTAAEFRAKCREYAATQVDGQRKDFIRLGVLGDWSHPYLTMDFK
                     TEANIIRALGKIIGNGHLHKGAKPVHWCVDCRSALAEAEVEYYDKTSPSIDVAFQAVD
                     QDALKAKFAVSNVNGPISLVIWTTTPWTLPANRAISIAPDFDYALVQIDGQAVILAKD
                     LVESVMQRIGVTDYTILGTVKGAELELLRFTHPFMGFDVPAILGDHVTLDAGTGAVHT
                     APGHGPDDYVIGQKYGLETANPVGPDGTYLPGTYPTLDGVNVFKANDIVVALLQEKGA
                     LLHVEKMQHSYPCCWRHKTPIIFRATPQWFVSMDQKGLRAQSLKEIKGVQWIPDWGQA
                     RIESMVANRPDWCISRQRTWGVPMSLFVHKDTEELHPRTLELMEEVAKRVEVDGIQAW
                     WDLDAKEILGDEADQYVKVPDTLDVWFDSGSTHSSVVDVRPEFAGHAADMYLEGSDQH
                     RGWFMSSLMISTAMKGKAPYRQVLTHGFTVDGQGRKMSKSIGNTVSPQDVMNKLGADI
                     LRLWVASTDYTGEMAVSDEILKRAADSYRRIRNTARFLLANLNGFDPAKDMVKPEEMV
                     VLDRWAVGCAKAAQEDILKAYEAYDFHEVVQRLMRFCSVEMGSFYLDIIKDRQYTAKA
                     DSVARRSCQTALYHIAEALVRWMAPILSFTADEVWGYLPGEREKYVFTGEWYEGLFGL
                     ADSEAMNDAFWDELLKVRGEVNKVIEQARADKKVGGSLEAAVTLYAEPELSAKLTALG
                     DELRFVLLTSGATVADYNDAPADAQQSEVLKGLKVALSKAEGEKCPRCWHYTQDVGKV
                     AEHAEICGRCVSNVAGDGEKRKFA"
     gene            4701..5195
                     /gene="lspA"
                     /locus_tag="IRB70_004425"
     CDS             4701..5195
                     /gene="lspA"
                     /locus_tag="IRB70_004425"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBC0634263.1"
                     /translation="MSQSICSTGLRWLWLVVVVLIIDLGSKYLILQNFALGDTVPLFP
                     SLNLHYARNYGAAFSFLADSGGWQRWFFAGIAIGISVILAVMMYRSKATQKLNNIAYA
                     LIIGGALGNLFDRLWHGFVVDMIDFYVGDWHFATFNLADTAICVGAALIVLEGFLPSK
                     AKKQ"
     gene            5283..5732
                     /gene="fkpB"
                     /locus_tag="IRB70_004426"
     CDS             5283..5732
                     /gene="fkpB"
                     /locus_tag="IRB70_004426"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FKBP-type peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBC0634264.1"
                     /translation="MSESVQSNSAVLVHFTLKLDDGTTAESTRNNGKPALFRLGDASL
                     SEGLEQHLLGLKVGDKTTFSLEPDAAFGVPSPDLIQYFSRREFMDAGEPEIGAIMLFT
                     AMDGSEMPGVIREINGDSITVDFNHPLAGQTVHFDIEVLEIDPALEA"
     gene            5734..6684
                     /gene="ispH"
                     /locus_tag="IRB70_004427"
                     /gene_synonym="lytB"
     CDS             5734..6684
                     /gene="ispH"
                     /locus_tag="IRB70_004427"
                     /gene_synonym="lytB"
                     /EC_number="1.17.7.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005124087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-3-methylbut-2-enyl diphosphate
                     reductase"
                     /protein_id="HBC0634265.1"
                     /translation="MQILLANPRGFCAGVDRAISIVENALAIYGAPIYVRHEVVHNRY
                     VVDSLRERGAIFIEQISEVPDGAILIFSAHGVSQAVRNEAKSRDLTVFDATCPLVTKV
                     HMEVARASRRGEESILIGHAGHPEVEGTMGQYSNPEGGMYLVESPDDVWKLTVKNEEK
                     LSFMTQTTLSVDDTSDVIDALRKRFPKIVGPRKDDICYATTNRQEAVRALAEQAEVVL
                     VVGSKNSSNSNRLAELAQRMGKSAFLIDDAKDIQEEWVKEVKCVGVTAGASAPDILVQ
                     NVVARLQQLGGGEAITLEGREENIVFEVPKELRVDIREVD"
     gene            6750..7664
                     /gene="rihC"
                     /locus_tag="IRB70_004428"
     CDS             6750..7664
                     /gene="rihC"
                     /locus_tag="IRB70_004428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonucleoside hydrolase RihC"
                     /protein_id="HBC0634266.1"
                     /translation="MRLPIFLDTDPGIDDAVAIAAAIFAPELDLQLMTTVAGNVSVEK
                     TTRNALQLLHFWNAEIPLAQGAAVPLVRAPRDAASVHGESGMAGYDFVEHNRKPLGIP
                     AFLAIRDALMRAPEPVTLVAIGPLTNIALLLSQCPECKPYIRRLVIMGGSAGRGNCTP
                     NAEFNIAADPEAAACVFRSGIEIVMCGLDVTNQAILTPDYLATLPELNRTGKMLHALF
                     SHYRSGSMQSGLRMHDLCAIAWLVRPDLFTLKPCFVAVETQGEFTSGTTVVDIDGCLG
                     KPANVKVALDLDVKGFQQWVAEVLALAS"
     gene            7831..8652
                     /gene="dapB"
                     /locus_tag="IRB70_004429"
     CDS             7831..8652
                     /gene="dapB"
                     /locus_tag="IRB70_004429"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBC0634267.1"
                     /translation="MHDANIRVAIAGAGGRMGRQLIQAALALEGVQLGAALEREGSSL
                     LGSDAGELAGAGKTGVTVQSSLDAVKDDFDVFIDFTRPEGTLNHLAFCRQHGKGMVIG
                     TTGFDEAGKQAIRDAAADIAIVFAANFSVGVNVMLKLLEKAAKVMGDYTDIEIIEAHH
                     RHKVDAPSGTALAMGEAIAHALDKDLKDCAVYSREGHTGERVPGTIGFATVRAGDIVG
                     EHTAMFADIGERLEITHKASSRMTFANGAVRSALWLSSKESGLFDMRDVLDLNSL"
BASE COUNT         2000 a         2158 c         2472 g         2083 t
ORIGIN      
        1 tgtataggaa tttaattcaa aaatagagtg gtcttaagtt taatacctca atgtgtatca
       61 caatatccac attctttgta ggggagtctg gagattgagt agatattctt gttcagaatg
      121 tatcagccga tggttctacg attcttaagc cacgaagagt tcagaaagtg taacggcatg
      181 tctgcaaaag ccagcatctt ttgactatct ggcaaccggt agtgtgttct ctcacgcatc
      241 ataaaagcag caggcataaa aaaacccgct tgcgcgggct ttttcacaaa gcttcagcaa
      301 attggcgatt aagccagttt gttgatctgt gcagtcaggt tagccttatg acgtgcagct
      361 ttgtttttgt ggatcagacc tttagcagcc tgacggtcca cgatcggttg catttcgtta
      421 aatgctttct gtgcagcagc tttgtcgcca gcttcgatag ctgcgtatac tttcttgatg
      481 aaagtacgca tcatagagcg acggcttgcg ttgtgcttac gagccttttc agactgaatg
      541 gcgcgcttct tagctgattt gatattagcc aaggtccaac tcccaaatgt gttctatatg
      601 gacaattcaa aggccgagga atatgccctt ttagccttct tttgtcaatg gatttgtgca
      661 aataagcgcc gttaatgtgc cggcactcgt tacgtagtga tggcgcagga ttctaccagc
      721 ttgcggggtg tgaatacagc ttttccgcga taaaaattgc agcaggcggt cactttcttc
      781 ccgtgatttg cgccatggca atgaaaagcc acttctttct gatttcggta ctcaatcgcc
      841 ggttaacctt gaccgctgta caaggtatac tcggacgatt ttcactgttt tgagccagac
      901 atgaagctga tacgcggcat acataatctc agccaggccc cgcaagaagg gtgtgtgctg
      961 actattggta atttcgacgg cgtgcatcgc ggtcatcgcg cgctgttaca gggcttgcag
     1021 gaagaagggc gcaagcgcaa cttaccggtg atggtgatgc tttttgaacc tcaaccactg
     1081 gaactgtttg ctaccgataa agccccggca cggctgaccc ggctgcggga aaaactgcgt
     1141 taccttgcag agtgtggcgt tgattacgtg ctgtgcgtgc gtttcgacag gcgtttcgcg
     1201 gcgttaaccg cgcaaaattt catcagcgat cttctggtga agcatttgcg cgtaaaattt
     1261 cttgccgtag gtgatgattt ccgctttggc gctggtcgtg aaggcgattt cttgttatta
     1321 cagaaagctg gcatggaata cggcttcgat atcaccagta cgcaaacttt ttgcgaaggt
     1381 ggcgtgcgta tcagcagcac cgctgtgcgt caggcgctgg cggatgacaa tctggctctg
     1441 gcagaaagtt tactggggca cccgtttgcc atctccgggc gtgtagtcca cggtgatgaa
     1501 ttagggcgca ctataggttt cccgacggcg aatgtaccgc tacgccgtca ggtttccccg
     1561 gtgaaagggg tttatgcggt agaagtgctg ggcctcggtg aaaagccgtt acccggcgtg
     1621 gcaaacattg gaacacgccc aacggttgcc ggtattcgcc agcagctgga agtgcatttg
     1681 ttagatgttg caatggacct ttacggtcgc catatacaag tagtgctgcg taaaaaaata
     1741 cgcaatgagc agcgatttgc gtcgctggac gaactgaaag cgcagattgc gcgtgatgaa
     1801 ttaaccgccc gcgaattttt tgggctaaca aaaccggctt aagcctgtta tgtaatcaaa
     1861 ccgaaacacg gaaccgagaa tctgatgagt gactataaat caaccctgaa tttgccggaa
     1921 acagggttcc cgatgcgtgg cgatctcgcc aagcgcgaac cgggaatgct ggcgcgttgg
     1981 actgatgatg atctgtacgg catcatccgt gcggctaaaa aaggcaaaaa aaccttcatt
     2041 ctgcatgatg gccctcctta tgcgaatggc agcattcata ttggtcactc ggttaacaag
     2101 attctgaaag acattatcgt gaagtccaaa gggctttccg gttatgactc gccgtatgtg
     2161 cctggctggg actgccacgg tctgccgatc gagctgaaag tagagcaaga atacggtaag
     2221 ccgggtgaga aattcaccgc cgccgagttc cgcgccaagt gccgcgaata cgcggcgacc
     2281 caggttgacg gtcaacgcaa agactttatc cgtctgggcg tgctgggcga ctggtcgcac
     2341 ccgtacctga ccatggactt caaaactgaa gccaacatca tccgcgcgct gggcaaaatc
     2401 atcggcaacg gtcacctgca caaaggcgcg aagccagttc actggtgcgt tgactgccgt
     2461 tctgcgctgg cggaagcgga agttgagtat tacgacaaaa cttctccgtc catcgacgtt
     2521 gcttttcagg cggtcgatca ggatgcactg aaagcaaaat ttgccgtaag caacgttaac
     2581 ggcccaatct cgctggtgat ctggaccact acgccgtgga ctctgcctgc gaaccgcgca
     2641 atctctattg cacctgattt cgactatgcg ctggtgcaga tcgacggtca ggccgtgatt
     2701 ctggcgaaag atctggttga aagcgtaatg cagcgtatcg gcgtgaccga ttacaccatt
     2761 ctcggcacgg taaaaggtgc ggagcttgag ttgctgcgct ttacccatcc gtttatgggc
     2821 ttcgacgttc cggcaatcct cggcgatcac gttaccctgg atgccggtac cggtgccgtt
     2881 cacaccgcgc ctggccacgg cccggacgac tatgtgatcg gtcagaaata cggcctggaa
     2941 accgctaacc cggttggccc ggacggcact tatctgccgg gcacttatcc gacgctggat
     3001 ggcgtgaacg tcttcaaagc gaacgacatc gtcgttgcgc tgctgcagga aaaaggcgcg
     3061 ctgctgcacg ttgagaaaat gcagcacagc tatccgtgct gctggcgtca caaaacgccg
     3121 atcatcttcc gcgcgacgcc gcagtggttc gtcagcatgg atcagaaagg tctgcgtgcg
     3181 cagtcactga aagagatcaa aggcgtgcag tggatcccgg actggggcca ggcgcgtatc
     3241 gagtcgatgg ttgctaaccg tcctgactgg tgtatctccc gtcagcgcac ctggggcgta
     3301 ccgatgtcac tgttcgtgca caaagacacg gaagagctgc atccgcgtac tctcgaacta
     3361 atggaagaag tggcaaaacg cgttgaagtt gacggcatcc aggcgtggtg ggatcttgat
     3421 gcgaaagaga tcctcggcga tgaagctgat cagtacgtga aagtgccgga cacattggat
     3481 gtatggtttg actccggatc tacccactct tctgttgttg acgtgcgtcc ggaatttgcc
     3541 ggtcacgcag cggacatgta tctggaaggt tctgaccagc accgtggttg gttcatgtct
     3601 tccctaatga tctccaccgc gatgaaaggc aaagcgccgt atcgtcaggt actgacccac
     3661 ggctttaccg tggatggtca gggtcgcaag atgtctaaat ccatcggcaa taccgtttcg
     3721 ccgcaggatg tgatgaacaa actgggcgcg gatattctgc gtctgtgggt ggcatcaacc
     3781 gactacaccg gtgaaatggc cgtttctgac gagatcctga aacgtgctgc cgatagctat
     3841 cgtcgtatcc gtaacaccgc gcgcttcctg ctggcaaacc tgaacggttt tgatccagca
     3901 aaagatatgg tgaaaccgga agagatggtg gtactggatc gctgggccgt aggttgtgcg
     3961 aaagcggcac aggaagacat cctcaaggcg tacgaagcat acgatttcca cgaagtggta
     4021 cagcgtctga tgcgcttctg ctccgttgag atgggttcct tctacctcga catcatcaaa
     4081 gaccgtcagt acaccgccaa agcggacagt gtggcgcgtc gtagctgcca gactgcgctg
     4141 tatcacatcg cagaagcgct ggtgcgctgg atggcaccaa tcctctcctt caccgctgat
     4201 gaagtgtggg gctacctgcc gggcgaacgt gaaaaatacg tcttcaccgg tgagtggtac
     4261 gaaggcctgt ttggcctggc agacagtgaa gcgatgaacg atgcgttctg ggacgagctg
     4321 ttgaaagtgc gtggcgaagt gaacaaagtc attgagcaag cgcgtgccga caagaaagtg
     4381 ggtggctcgc tggaagcggc agtaaccttg tatgcagaac cggaactgtc ggcgaaactg
     4441 accgcgctgg gcgatgaatt acgatttgtc ctgttgacct ccggcgctac cgttgcagac
     4501 tataacgacg cacctgctga tgctcagcag agcgaagtac tcaaagggct gaaagtcgcg
     4561 ttgagtaaag ccgaaggtga gaagtgccca cgctgctggc actacaccca ggatgtcggc
     4621 aaggtggcgg aacacgcaga aatctgcggc cgctgtgtca gcaacgtcgc cggtgacggt
     4681 gaaaaacgta agtttgcctg atgagtcaat cgatctgttc aacagggcta cgctggctgt
     4741 ggctggtggt agtcgtgctg attatcgatc tgggcagcaa atacctgatc ctccagaact
     4801 ttgctctggg ggatacggtc ccgctgttcc cgtcgcttaa tctgcattat gcgcgtaact
     4861 atggcgcggc gtttagtttc cttgccgata gcggcggctg gcagcgttgg ttctttgccg
     4921 gtattgcgat tggtattagc gtgatcctgg cagtgatgat gtatcgctcg aaggccacgc
     4981 agaagctaaa caatatcgct tatgcgctga ttattggcgg cgcgctgggc aacctgttcg
     5041 accgcctgtg gcacggcttc gttgtcgata tgatcgactt ctacgtcggc gactggcact
     5101 tcgccacctt caaccttgcc gatactgcca tttgtgtcgg tgcggcactg attgtgctgg
     5161 aaggtttttt gccttctaaa gcgaaaaaac aataataaac cctgccggat aaggcctaca
     5221 gattgctgcg aaatcgtagg ccgcatccgg caaaaatcct caaaatataa gagcaaacct
     5281 gcatgtctga atctgtacag agcaatagcg ccgtcctggt gcacttcacg ctaaaactcg
     5341 acgatggcac caccgccgag tctacccgca acaacggtaa accggcgctg ttccgcctgg
     5401 gtgatgcttc tctttctgaa gggctggagc aacacctgtt ggggctgaaa gtgggcgata
     5461 aaaccacctt ctcgttggag ccagatgcgg cgtttggcgt gccgtcaccg gacctgattc
     5521 agtacttctc ccgccgtgaa tttatggatg caggcgagcc agaaattggc gcaatcatgc
     5581 tttttaccgc aatggatggc agtgagatgc ctggcgtgat ccgcgaaatt aacggcgact
     5641 ccattaccgt tgatttcaac catccgctgg ccgggcagac cgttcatttt gatattgaag
     5701 tgctggaaat cgatccggca ctggaggcgt aacatgcaga tcctgttggc caacccgcgt
     5761 ggtttttgtg ccggggtaga ccgcgctatc agcattgttg aaaacgcgct ggccatttac
     5821 ggcgcaccga tatatgtccg tcacgaagtg gtacataacc gctatgtggt cgatagcttg
     5881 cgtgagcgtg gggctatctt tattgagcag attagcgaag taccggacgg cgcgatcctg
     5941 attttctccg cacacggtgt ttctcaggcg gtacgtaacg aagcaaaaag tcgcgatttg
     6001 acggtatttg acgcgacctg tccgctggtg accaaagtgc atatggaagt cgcccgcgct
     6061 agtcgccgtg gcgaagaatc tattctcatc ggtcacgccg ggcacccgga agtggaaggc
     6121 acgatgggtc agtacagcaa cccggaaggg ggaatgtatc tggttgaatc accagacgat
     6181 gtgtggaaac tgacggtcaa aaacgaagag aaactctcct ttatgaccca gaccacgctg
     6241 tcggtggatg acacgtctga tgtgatcgac gcgctgcgta aacgcttccc gaaaattgtc
     6301 ggtccgcgca aagatgacat ctgctacgcc acgactaacc gacaggaagc ggtacgtgcc
     6361 ctggccgaac aggcggaagt tgtgctggtg gtcggttcga aaaactcctc taactccaac
     6421 cgtctggcgg agctggccca gcgtatgggc aaaagcgcgt ttttgattga tgatgcgaaa
     6481 gatatccagg aagagtgggt gaaagaggtt aaatgcgtcg gcgtgactgc gggcgcatcg
     6541 gctccggata ttctggtgca gaatgtggtg gcacgtttgc aacagctggg cggtggtgaa
     6601 gccattacgc tggaaggacg tgaagaaaac attgttttcg aagtgccgaa agagctgcgt
     6661 gtcgatattc gtgaagtcga ttaagtcatt agcagcctaa gttatgcgaa aatgccggtc
     6721 ttgttaccgg cattttttat ggagaaaaca tgcgtttacc tatcttcctc gatactgacc
     6781 ccggcattga cgatgccgtc gccattgccg ccgcgatttt tgcacccgaa ctcgacctgc
     6841 aactgatgac caccgtcgcg ggtaatgtct cggttgagaa aactacccgc aatgccctgc
     6901 aactgctgca tttctggaat gcggagattc cgctcgccca aggggccgct gtgccgctgg
     6961 tacgcgcacc gcgtgatgcg gcatctgtgc acggcgaatc gggaatggct ggctacgact
     7021 ttgttgagca caaccgaaag ccgctcggga taccggcgtt tctggcgatt cgggatgccc
     7081 tgatgcgtgc accagagcct gttaccctgg tggccattgg cccgttaacc aatattgcgc
     7141 tgttactttc acaatgcccg gaatgcaagc cgtatattcg ccgtctggtg atcatgggtg
     7201 gttctgccgg acgcggcaac tgtacgccaa acgccgagtt taatatcgct gccgatccag
     7261 aagcggctgc ctgtgtcttc cgtagcggaa tcgaaatcgt catgtgcggt ctggatgtca
     7321 ccaatcaggc aatattaacc cctgactatc tcgctacttt gccggagttg aatcgcaccg
     7381 gaaaaatgct tcatgcactg tttagccact accgtagcgg cagtatgcaa agcggtctgc
     7441 gaatgcacga tctctgcgcc atcgcctggc tggtgcgccc ggacttattc accctcaagc
     7501 cgtgttttgt cgcggtagaa actcaaggcg aatttacctc aggcacgacg gtggttgata
     7561 tcgacggttg cctgggcaaa ccagccaatg taaaggtggc attggatctg gatgtgaaag
     7621 gcttccagca gtgggtggct gaggtgctgg ctctggcgtc gtaacctgtc acatgttatc
     7681 ggcatgcagt cattcatcga ctcatgcctt tcactgatat ccctccctgt ttatcattaa
     7741 tttctaatta tcagcgtttt tggctggcgg cgtagcgatg cgctggttac tctgaaaacg
     7801 gtctatgcaa attaacaaaa gagaatagct atgcatgatg caaacatccg cgttgccatc
     7861 gcgggagccg gggggcgtat gggccgccag ttgattcagg cggcgctggc attagaaggc
     7921 gtgcagctgg gcgcggcgct ggagcgcgaa ggatcttctt tactgggcag cgacgccggt
     7981 gagctggctg gtgcagggaa aacaggcgtt accgtgcaaa gcagcctcga tgcggtaaaa
     8041 gatgattttg atgtgtttat cgattttacc cgtccggaag gtacgctgaa ccatctcgct
     8101 ttttgtcgcc agcatggcaa agggatggtg atcggcacta cggggtttga cgaagccggt
     8161 aaacaggcga ttcgtgacgc cgccgccgat attgcgattg tctttgccgc caattttagc
     8221 gttggcgtta acgtcatgct taagctgctg gagaaagcag ccaaagtgat gggtgactac
     8281 accgatatcg aaattattga agcacatcat agacataaag ttgatgcgcc gtcaggcacc
     8341 gcactggcaa tgggagaggc gatcgcccac gcccttgata aagatctgaa agattgcgcg
     8401 gtctacagtc gtgaaggcca caccggtgaa cgtgtgcctg gcaccattgg ttttgccacc
     8461 gtgcgtgcag gtgacatcgt tggcgaacat accgcgatgt ttgccgatat tggcgagcgt
     8521 ctggagatca cccataaggc gtccagccgc atgacatttg ctaacggcgc ggtaagatcg
     8581 gctttgtggt tgagtagtaa ggaaagtggt ctttttgata tgcgagatgt gcttgatctc
     8641 aatagtttgt aaccacaaaa tatttgttat ggtgcaagaa taacacattt aatttattga
     8701 ttataaaggg ctt
//
LOCUS       DADXDL010000138         8338 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.138, whole genome shotgun sequence.
ACCESSION   DADXDL010000138 DADXDL010000000
VERSION     DADXDL010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8338
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.138"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1435
                     /locus_tag="IRB70_004430"
     CDS             <1..1435
                     /locus_tag="IRB70_004430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="3'-5' exoribonuclease"
                     /protein_id="HBC0634268.1"
                     /translation="NQSATDTLSSPVPETDAVETAIPDNEKTECKVEVEPSVEREGPF
                     YFLFTDKDGEKYGRANKLSGLDKALSAGATEITKEEYFARKNGTYSGSQQNTGASDTT
                     AQPGSVKVTADEVNKIMQAANISQPDADELLAVSRGEFVEGISDPNDPKWIKGIQTRD
                     SVNQNQQETEQNDQKAEQNSPNTQQNEPETKQPEPVVQQEPEKICTACGQSGGGNCPD
                     CGAVMGDATYQEIFDGENQPEVQKNDLEEMEGTAHQHKENTGSNQHHASDSETGEASD
                     PLIKVNGHHNLTSTSRAGIHLMIDLETMGKNPDAPIISIGAIFFDPQTGDMGPEFSKT
                     IDLETAGGVIDRDTIKWWLKQSREAQSAIMTDEIPLDDALLQLREFIDENSGEFFVHV
                     WGNGANFDNTILRRSYERQGIPCPWRYYNDRDVRTIVELGKAIDFDARTAIPFEGERH
                     NALDDARYQAKYVSAIWQKLIPSQADS"
     gene            1508..1759
                     /locus_tag="IRB70_004431"
     CDS             1508..1759
                     /locus_tag="IRB70_004431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000005552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excisionase family protein"
                     /protein_id="HBC0634269.1"
                     /translation="MSEVIMIVSPGKWVSEEQLIALKGIKKGTLKKAREKSFMEGREY
                     KHVAHDGMPWDNSPCFYNLEEIDRWIERQASARPRRHLT"
     gene            1794..3074
                     /locus_tag="IRB70_004432"
     CDS             1794..3074
                     /locus_tag="IRB70_004432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001686441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3596 domain-containing protein"
                     /protein_id="HBC0634270.1"
                     /translation="MKYPTGVENHGGKLRIWFVYKGVRVRENLGVPDTAKNRRVAGEL
                     RASVCYAIKTGVFDYAKQFPSSRNLEKFGEARQDLTIKELAEKFLALKETEVAKTSLN
                     TYRAVIKNILSIIGEKNLASSINKEKLLEVRKELLTGYQIPKSNYIVTQPGRSAVTVN
                     NYMTNLNAVFQFGVDNGYLADNPFKGISPLKESRTIPDPLSREEFIRLIDACRNQQAK
                     NLWCVSVYTGVRPGELCALGWEDIDLKNGTMMIRRNLAKDRFTVPKTQAGTNRVIHLI
                     KPAIDALRSQMTLTRLSKEHIIDVHLREYGRTEKHKCTFVFQPEVSARVKNYGDHFTV
                     DSIRQMWDAAIKRAGLRHRKSYQSRHTYACWSLTAGANPAFIANQMGHADAQMVFQVY
                     GKWMSENNNAQVALLNTQLSEFAPTMPHNEAMKN"
     gene            complement(3076..3204)
                     /locus_tag="IRB70_004433"
     CDS             complement(3076..3204)
                     /locus_tag="IRB70_004433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter"
                     /protein_id="HBC0634271.1"
                     /translation="MTIEKHERSTKDLVKAAVSGWLGTALEFMDFKSHTCQLFDKY"
     gene            complement(3262..4281)
                     /locus_tag="IRB70_004434"
     CDS             complement(3262..4281)
                     /locus_tag="IRB70_004434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Zn-dependent oxidoreductase"
                     /protein_id="HBC0634272.1"
                     /translation="MKSILIEKPNQLAIIEREIPTPSAGEVRVKVKLAGICGSDSHIY
                     RGHNPFAKYPRVIGHEFFGVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNV
                     CTTLAVLGVHADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEPFTIAANVTGHGQPTE
                     NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAINNSQTPL
                     GEIFAEKGIKPTLIIDAACHPSILKEAVTLASPAARIVLMGFSSEPSEVIQQGITGKE
                     LSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFEQDQKHCCKVL
                     LTFSE"
     gene            complement(4293..5507)
                     /gene="rspA"
                     /locus_tag="IRB70_004435"
     CDS             complement(4293..5507)
                     /gene="rspA"
                     /locus_tag="IRB70_004435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="starvation-sensing protein RspA"
                     /protein_id="HBC0634273.1"
                     /translation="MKIVKAEVFVTCPGRNFVTLKITTEDGITGLGDATLNGRELSVA
                     SYLQDHLCPQLIGRDAHRIEDIWQFFYKGAYWRRGPVTMSAISAVDMALWDIKAKAAN
                     MPLYQLLGGASREGVMVYCHTTGHSIDEALDDYARHQELGFKAIRVQCGIPGMKTTYG
                     MSKGKGLAYEPATKGQWPEEQLWSTEKYLDFMPKLFDAVRNKFGFNEHLLHDMHHRLT
                     PIEAARFGKSIEDYRMFWMEDPTPAENQECFRLIRQHTVTPIAVGEVFNSIWDCKQLI
                     EEQLIDYIRTTLTHAGGITGMRRIADFASLYQVRTGSHGPSDLSPVCMAAALHFDLWV
                     PNFGVQEYMGYSEQMLEVFPHNWTFDNGYMHPGDKPGLGIEFDEKLAAKYPYEPAYLP
                     VARLEDGTLWNW"
     gene            complement(5713..6039)
                     /locus_tag="IRB70_004436"
     CDS             complement(5713..6039)
                     /locus_tag="IRB70_004436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfA family protein"
                     /protein_id="HBC0634274.1"
                     /translation="MIKTTLLFFATALCEIIGCFLPWLWLKRNASIWLLLPAGISLAL
                     FVWLLTLHPAASGRVYAAYGGVYVCTALIWLRVVDGVKLTLYDWTGALIALCGMLIIV
                     AGWGRT"
     gene            6174..6515
                     /locus_tag="IRB70_004437"
     CDS             6174..6515
                     /locus_tag="IRB70_004437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1283 family protein"
                     /protein_id="HBC0634275.1"
                     /translation="MKITLSKRIGLLAFLLPCALALSTTVHAETNKLVIESGDSAQSR
                     QHAAMEKEQWNDTRNLRQKVNKRTEKEWDKADAAFDNRDKCEQSANINAYWEPNTLRC
                     LDRRTGRVITP"
     gene            6550..7110
                     /gene="speG"
                     /locus_tag="IRB70_004438"
     CDS             6550..7110
                     /gene="speG"
                     /locus_tag="IRB70_004438"
                     /EC_number="2.3.1.57"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="spermidine N1-acetyltransferase"
                     /protein_id="HBC0634276.1"
                     /translation="MPSAHSVKLRPLEREDLRYVHQLDNNASVMRYWFEEPYEAFVEL
                     SDLYDKHIHDQSERRFVVECDGEKAGLVELVEINHVHRRAEFQIIISPEYQGKGLATR
                     AAKLAMDYGFTVLNLYKLYLIVDKENEKAIHIYRKLGFTVEGELMHEFFINGQYRNAI
                     RMCIFQHQYLAEHKTPGQTLLKPTAQ"
     gene            complement(7113..7823)
                     /locus_tag="IRB70_004439"
     CDS             complement(7113..7823)
                     /locus_tag="IRB70_004439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416102.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YnfC family lipoprotein"
                     /protein_id="HBC0634277.1"
                     /translation="MKYKLLPCLLAIFLTGCDRTEVTLSFTPEMASFSNEFDFDPLRG
                     PVKDFTQTLMDEQGEVTKRVSGTLSEEGCFDSLELLDLENNTVVALVLDANYYRDAQT
                     LEKRVRLQGKCQLAELPSAGVSWETDDNGFVINASSKQMQMEYRYDDQGYPLGKTTKS
                     NDKTLSVSATPSTDPIKKLDYTAVTLLNNQRVGNVKQSCEYDSHANPVDCQLIIVDEG
                     VKPAVERVYTIKNTIDYY"
     gene            7931..8236
                     /locus_tag="IRB70_004440"
     CDS             7931..8236
                     /locus_tag="IRB70_004440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707474.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1161 domain-containing protein"
                     /protein_id="HBC0634278.1"
                     /translation="MKLSTCCAALLLALASPAVLAAPGSCERIQSDISQRIINNGVPE
                     SSFTLSIVPNDQVDQPDSQVVGHCANDTHKILYTRTTSGNVSAPAQSTQDGAPAEPQ"
BASE COUNT         2440 a         2000 c         1872 g         2026 t
ORIGIN      
        1 aaatcagagc gcaactgata ctctctcgtc gccagtacca gaaactgatg cagtggaaac
       61 ggcaattcca gacaacgaaa aaaccgaatg caaagtggaa gtcgaaccat ctgtagaacg
      121 tgaggggccg ttctacttcc tcttcaccga caaggatggc gaaaaatacg gtcgcgcaaa
      181 taaactttct ggtctggata aggcgctgtc tgctggggct actgaaatca cgaaagaaga
      241 atatttcgcc cgcaaaaacg gtacatactc aggttcacaa caaaatactg gtgcatctga
      301 cacgaccgca caaccagggt cagtaaaagt taccgctgac gaagtaaaca aaattatgca
      361 ggcagccaat atcagccagc ctgacgccga tgaactgctt gcagtatcac gtggtgaatt
      421 tgttgaaggg attagcgacc cgaatgatcc gaaatggatt aaggggatcc agacccgcga
      481 ttctgtgaac cagaaccagc aagaaacgga acagaacgac cagaaagcgg aacaaaacag
      541 cccaaatacg caacaaaacg agccagaaac gaaacaacct gaaccagtag tgcaacagga
      601 accggaaaag atctgcaccg cctgcggtca gagcggtggc ggcaactgcc ctgattgtgg
      661 tgcggtgatg ggtgacgcaa cataccagga aatattcgat ggagagaatc agcctgaagt
      721 tcagaaaaat gatctggagg aaatggaagg cactgcgcat cagcacaagg agaacactgg
      781 cagcaatcag catcatgcca gcgatagtga aactggcgag gcgtcagatc ccttaattaa
      841 ggtgaacggt catcataatc tcacatccac cagcagagcg gggattcatc tgatgatcga
      901 ccttgaaacc atgggaaaaa atcccgatgc cccgattatc tcaataggtg caatattttt
      961 cgatccgcaa accggagata tgggaccgga atttagtaag actatcgatc tggaaactgc
     1021 tggcggagtc attgatcggg acaccattaa atggtggctt aaacaatcac gcgaagcgca
     1081 atctgccatt atgaccgatg aaatcccgtt agatgatgca ctgttacaat tgcgggaatt
     1141 tatcgacgaa aactccggtg aattttttgt tcatgtctgg ggaaatggag ccaacttcga
     1201 caacacgatt ttgcgccgtt catacgaacg gcaggggatc ccctgcccgt ggcgttacta
     1261 caacgatcgc gatgtacgca caatcgttga gctggggaaa gccatagact tcgatgccag
     1321 aacggctatt ccattcgaag gtgagcgcca taatgcactt gatgacgccc gttaccaggc
     1381 aaaatacgtt tcagctatct ggcaaaaact gatcccgagt caggctgatt cttaatgttc
     1441 aactgtcgcc ggttgtgact ggtattctgc aaccggcgct cgtctgatgt aagagataaa
     1501 gaaatcgatg agcgaagtaa tcatgattgt ctctcccggc aaatgggtat ccgaagagca
     1561 gttaattgcg ctgaaaggaa taaaaaaagg tacgttaaaa aaggcccggg aaaaatcgtt
     1621 tatggaagga agggaatata agcatgtcgc tcatgacggt atgccatggg ataacagtcc
     1681 atgcttttac aacctggaag aaattgatcg ctggattgag cgccaggcat cagcaagacc
     1741 aagacgtcat cttacttgac taaaagccac actaactaat gagagaagtt gaaatgaaat
     1801 atccgacagg cgtggaaaac catggaggga aattacgtat ctggtttgtt tataaaggcg
     1861 taagagtcag ggaaaacctg ggggttcctg acacagcaaa aaacaggcgc gttgcaggtg
     1921 agctacgcgc ctctgtttgt tacgcaataa aaactggtgt tttcgactat gcaaaacagt
     1981 ttccctcctc acgcaatctg gaaaaatttg gtgaggcccg acaagattta accataaaag
     2041 aactggctga aaaatttctg gcactgaaag aaactgaagt cgcaaaaaca tcactcaaca
     2101 cataccgtgc cgtcatcaaa aatatcctga gcataatcgg tgaaaaaaat cttgcctcat
     2161 cgattaataa agaaaaatta ctggaggttc gtaaagagct actgactgga taccagatcc
     2221 ccaaaagtaa ctatattgtt acacaaccag ggagatcggc tgtaactgta aataattaca
     2281 tgacaaatct taacgccgtg ttccagtttg gtgttgataa cggttacctg gcagataacc
     2341 cgtttaaggg gatctcgcca ttaaaggaat caagaaccat tccggatcct ctttcgcggg
     2401 aggaattcat ccgtcttatc gatgcgtgca gaaatcagca agccaaaaat ttatggtgtg
     2461 tttctgttta tactggcgtt cgccctggtg agctgtgtgc acttggatgg gaggacatag
     2521 atctgaaaaa tggaacaatg atgatcagga gaaatttagc aaaagaccgt ttcacggtac
     2581 caaaaacaca ggcgggaacc aatcgggtca ttcatcttat taagccagca atcgacgctc
     2641 tccggagtca gatgacatta acgagactga gcaaagagca tatcattgat gttcacctca
     2701 gagagtatgg cagaacagaa aaacataaat gcacctttgt ttttcaacct gaagtgtcag
     2761 cgagagtaaa aaattatggt gaccatttta ccgttgactc aataaggcag atgtgggacg
     2821 cagcgataaa acgtgccgga ctccgccatc gaaaatcata tcagtcgaga catacttatg
     2881 cctgctggtc gctgacagct ggtgctaacc cggcatttat agcaaaccag atgggccatg
     2941 cagatgcgca aatggtattt caggtatacg gaaaatggat gtctgaaaac aataatgcac
     3001 aggtagcttt gttaaataca cagttaagcg agtttgcccc aaccatgccc cataacgaag
     3061 caatgaaaaa ttaatttaat atttatcaaa tagttgacac gtatgactct tgaaatccat
     3121 aaattcaagc gcagtgccca gccatcccga tactgctgct ttcaccaaat ccttagtgct
     3181 tctttcgtgt ttttctattg tcataatggt tatctctaaa aaagaggtaa gatgcgtact
     3241 acttactcgc cgttattggt attattcaga aaaagtgagt aagactttgc agcaatgctt
     3301 ttgatcctgt tcaaataaac taatggcatc agcaacatgc tggaaatcaa acgtatgggt
     3361 aattagtttt tctggtttaa ttaacccttt acttaaccag tcgataacga ccgggaattt
     3421 atttgcattt aagcgtgaag agaaaataga gagttctttt ccggtaattc cttgctgaat
     3481 cacttcagac ggttcactgg agaagcccat caatacaata cgtgccgctg gagaagccag
     3541 cgttacggcc tctttcagga tagaaggatg acaagccgca tcgataatta atgtcggctt
     3601 tatgcctttt tcagcgaaaa tctcgccaag cggtgtctgg ctgttattaa tcgcccagtc
     3661 tgccccgctc tctttcgctt tttccagtcg ttcatcaatg cgatcggcaa caatcacatt
     3721 cttaacgtta tagacgcctt ttaatacctg aacgatcgtc aggccgattg gaccggcacc
     3781 ataaaccaga acggtatcat tttcagtcgg ttgaccatgt ccggttacgt tagccgcaat
     3841 ggtaaaaggt tcgatcatta ccgcatattg atcggccact gcttcaggaa ttttccacgc
     3901 attttttgcc ggaaccacgg catattcact gaaaccaccg tcagcgtgca cacctaatac
     3961 agccagtgtc gtacaaacgt tcggtttacc tatagagcac ggatagcaat gcccacagct
     4021 gaccaccgga tcgacagcaa cacgttcacc gactctggcg ctttccacgc cttcacccac
     4081 tgcatcaatg acgccaaaga attcatgacc aatgacgcgc ggatatttcg caaaaggatt
     4141 atgcccacga taaatatggc tatctgaacc acaaattccg gcaagtttca cttttactcg
     4201 tacttcaccc gctgacgggg tgggtatttc gcgttcgata attgccagtt gattcggttt
     4261 ttcaattaaa atgcttttca ttatcttact ccttaccagt tccacagcgt gccatcttcc
     4321 agacgtgcga ctggcagata agcaggttca tagggatatt tcgccgccag cttttcatcg
     4381 aattcgatgc caagacccgg tttgtctccc ggatgcatat agccgttatc aaaagtccag
     4441 ttgtgcggga agacttcaag catttgttcg gaataaccca tgtattcctg gacaccgaaa
     4501 ttggggaccc acagatcaaa gtgcagcgcc gcagccatgc agactggcga caaatcggaa
     4561 ggaccgtgtg agccagtacg tacctgatac aacgaagcaa aatcggcaat ccggcgcata
     4621 ccggtaatcc cccccgcgtg agtcagcgtg gtgcggatat agtcgataag ttgttcttca
     4681 atcagctgtt tgcagtccca gatgctgttg aagacttcac ccactgcaat tggcgtgacg
     4741 gtgtgttggc gaatcaggcg gaaacactcc tggttttccg caggcgtcgg atcttccatc
     4801 cagaacatgc gataatcttc aatgctttta ccaaagcgtg ctgcttcaat aggcgttaag
     4861 cgatggtgca tgtcatgcag caaatgttca ttaaaaccaa acttgttacg taccgcgtca
     4921 aacaatttcg gcatgaaatc gaggtatttc tccgtcgacc acagctgctc ttccggccac
     4981 tgtcctttgg ttgcgggttc ataagccaga cctttacctt tcgacatgcc ataggtggtt
     5041 ttcataccag ggattccgca ctgcacgcgg atggctttga atcccagctc ctgatgacgg
     5101 gcataatcat ccagagcttc atcaatactg tgaccggtgg tatggcaata aaccatcacc
     5161 ccttcacgag acgcgccgcc gagtaactgg taaagcggca tgttggcagc tttggcttta
     5221 atatcccaca gcgccatatc aaccgctgaa atggccgaca tcgtaaccgg accgcgacgc
     5281 cagtaagcac ctttatagaa aaactgccag atatcttcga tacggtgcgc atcgcgacca
     5341 ataagctgcg gacaaaggtg atcctgcaaa taagaggcca cggaaagctc acgtccattg
     5401 agggtggcat ccccaaggcc cgtaataccg tcctcagtgg tgatttttaa tgtgacgaaa
     5461 ttacgccccg gacaggtaac aaaaacttca gcctttacga tcttcatgtt cgattccttg
     5521 catcgcttgt cgtgatgcat gaaatctacg caactgagct actaccatac aagtatgaag
     5581 atcaaaaaaa gccggagtga tcacaaaaaa aggcgtatat ttgcgccgtg aatggttgac
     5641 aaaagatgaa atagaatacc ttttgtcagc tgacacttcc tcgtatctta ttgataaaat
     5701 ggatttatgt tcctacgtgc gcccccagcc cgcaacaatg atcaacatgc cgcaaagcgc
     5761 aatcaacgcc cccgtccagt cataaagagt cagtttcacg ccatccacaa cgcgcagcca
     5821 aatcaacgcc gtgcagacat aaacgccacc ataagccgcg taaacacgcc cactcgccgc
     5881 aggatgcaac gttaacaacc agacaaacag cgccagtgaa atccctgccg gaagcaacag
     5941 ccagatactg gcgtttcgct tcaaccacag ccagggcaaa aagcacccaa taatttcaca
     6001 cagcgcagta gcaaaaaata gtaacgttgt tttaatcatc tttgtcactt attgacatca
     6061 tgtatagtta taggacgaca taatatcatc aatataaaca ccctccttga acgttttgcg
     6121 ttcgcagtgg atggtgtaga atcagcttta atcattcata cagggaatga attatgaaaa
     6181 tcactctcag caaacgaatc ggcctgctcg cttttctgct gccttgcgca ctggcattga
     6241 gcacaactgt tcatgccgaa actaacaaac tggtgattga gtctggcgac agtgcacaaa
     6301 gccgccagca cgccgctatg gaaaaagagc aatggaatga cacgcgcaat ctgcgccaga
     6361 aagtgaataa acgcactgaa aaagagtggg ataaagccga cgccgctttt gataaccgcg
     6421 ataaatgtga gcaaagcgcc aacatcaatg cctactggga gccaaatact ttgcgctgcc
     6481 tggaccgtcg aactggccgc gttattaccc cctaacctgt tattgattta aggaatgtaa
     6541 ggacacgtta tgccaagcgc ccacagtgtt aagctacgcc cgctggagcg tgaagattta
     6601 cgctatgtac atcaactcga caataacgcc agtgtgatgc gttactggtt tgaggaaccc
     6661 tacgaagcct ttgttgaact ctctgatctg tacgataagc atattcacga tcagagcgaa
     6721 cggcgctttg tggtggaatg tgacggcgaa aaagccggtc tggtggagct ggtggaaatt
     6781 aaccatgttc atcgccgcgc agaatttcag ataattatct ccccggaata tcaggggaaa
     6841 ggtctggcaa cgcgtgccgc aaaattagca atggactatg gcttcaccgt tctcaatctc
     6901 tataagctgt atctgatcgt cgataaagag aatgaaaaag cgattcacat ttaccgcaag
     6961 cttggcttta cggttgaagg tgaattgatg catgagttct ttattaatgg tcaatatcgg
     7021 aatgccattc gcatgtgcat attccagcat cagtatctgg cagagcacaa aacaccgggt
     7081 cagactctcc tgaagccgac cgcacaatag cattaataat aatcgatagt atttttgatg
     7141 gtgtaaaccc gttcgacggc gggttttact ccttcatcaa caatgattag ctgacagtct
     7201 accggattgg cgtgactgtc atattcacag ctctgtttta cattaccaac ccgttgatta
     7261 ttcagtaaag taaccgctgt gtaatctaat tttttgatcg gatccgttga tggcgtagcg
     7321 ctaacagata atgttttgtc gttacttttc gtggttttac ccagcggata accctgatca
     7381 tcatagcgat attccatctg catctgtttg ctgctggcat taatcacaaa gccattatca
     7441 tcggtttccc aactcacccc ggcagaaggt aattctgcta gctggcattt tccctgcaaa
     7501 cgaactcttt tctccagtgt ctgggcatca cggtaataat tggcgtccag taccagggca
     7561 accacggtat tattttccag atccagtaat tcgagagaat caaaacagcc ttcttccgac
     7621 aaagtccccg aaacacgttt cgtcacttca ccttgctcat ccattaatgt ctgagtgaaa
     7681 tcttttacgg gaccacgcag cggatcaaaa tcgaattcat tagagaaact ggccatctcc
     7741 ggggtaaatg aaagtgttac ttctgtgcgg tcacatcctg tgaggaatat cgcgagtaag
     7801 catggcagta atttgtattt cacaacagtc acctgagagt agagatgatt ctcaatcata
     7861 gtagcaaata cagtacttta cacgttaaat gctatgctta aagaagttat cttcgcgtaa
     7921 ggagcttatg atgaaactct caacctgctg tgccgcgctt ctgctcgccc tcgcctcacc
     7981 cgcggtactc gccgcgccgg gatcctgcga gcgcatacag agcgatatat cacagcgcat
     8041 tatcaataat ggcgtacccg aaagcagctt cacgttaagt attgtaccca atgaccaggt
     8101 tgatcagcct gattcccagg tcgtcgggca ttgcgctaat gatacgcata aaattctcta
     8161 cacccgtacc accagcggta acgtctctgc tcccgcgcag tctacccagg atggcgcgcc
     8221 tgccgaaccg cagtaacaca ttatcgactg aacgccggat acgacacatc cggcgatttg
     8281 aacatacaac ataatcccac cttattactc atacccttct attgatatgg attaataa
//
LOCUS       DADXDL010000139         8309 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.139, whole genome shotgun sequence.
ACCESSION   DADXDL010000139 DADXDL010000000
VERSION     DADXDL010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8309)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8309)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8309
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.139"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            16..1740
                     /gene="iucA"
                     /locus_tag="IRB70_004441"
     CDS             16..1740
                     /gene="iucA"
                     /locus_tag="IRB70_004441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucA"
                     /protein_id="HBC0634279.1"
                     /translation="MILPSEKSATDVAAQCFLNALIRETKDWQLAEYPPDELIIPLDE
                     QKSLHFRVAYFSPTQHHRFAFPAHLVTASGSYPVDFTTLSRLIIDKLRHQLFLPVPLC
                     ETFHQRVLESYAHTQQTIDARHDWAILREKALNFGEAEQALLTGHAFHPAPKSHEPFN
                     RQEAERYLPDMAPHFPLRWFSVDKTQIAGESLHLNLQQRLTRFAAENAPQLLNELSDN
                     QWLFPLHPWQGEYLLQQVWCQALFAKGLIRDLGEAGTSWLPTTSSRSLYCATSRDMIK
                     FSLSVRLTNSVRTLSVKEVERGMRLARLTQTDGWQMLQARFPTFRVMQEDGWAGLRDL
                     NGNIMQESLFSLRENLLLEQPQSQTNVLVSLTQAAPDGGDSLLVSAVKRLSDRLGITV
                     QQAAHAWVDAYCQQVLKPLFTAEADYGLVLLAHQQNILVQMLGDLPVGFIYRDCQGSA
                     FMPHATEWLDTIDEAQAENIFTREQLLRYFPYYLLVNSTFAVTAALGAAGLDSEANLM
                     ARVRTLLAEVRDQVTHKTCLNYVLESPYWNVKGNFFCYLNDHNENTIVDPSVIYFDFA
                     NPLQAQEV"
     gene            1741..2688
                     /gene="iucB"
                     /locus_tag="IRB70_004442"
     CDS             1741..2688
                     /gene="iucB"
                     /locus_tag="IRB70_004442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N(6)-hydroxylysine O-acetyltransferase"
                     /protein_id="HBC0634280.1"
                     /translation="MSGANIVHSGYGLRCEKLDKPLNLGWGLDNSAVLHWPGELPTGW
                     LCDALDQIFIAAPQLSAVVLPWSEWCEEPQALTLFGQVQSDIIHRSAFWQLPLWLSSP
                     ANRASGEMVFDAEREIYFPQRPPRPQGEVYRRYDPRIRRMLSFRIADPVSDAERFTRW
                     MNDPRVEYFWEQSGSLEVQIAYLERQLTSKHAFPLIGCFDDRPFSYFEIYWAAEDRIG
                     RHYSWQPFDRGLHLLVGEQQWRGAHYVQSWLRGVTHYLLLNEPRTQRTVLEPRTDNQR
                     LFRHLEPAGYRTIKEFDFPHKRSRMVMADRHHFFTEVGL"
     gene            2688..4430
                     /gene="iucC"
                     /locus_tag="IRB70_004443"
     CDS             2688..4430
                     /gene="iucC"
                     /locus_tag="IRB70_004443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aerobactin synthase IucC"
                     /protein_id="HBC0634281.1"
                     /translation="MNHKDWDLVNRRLVAKMLSELEYEQVFHAESQGDDRYCINLPGA
                     QWRFIAERGIWGWLWIDAQTLRCADEPVLAQTLLMQLKQVLSMSDATVAEHMQDLYAT
                     LLGDLQLLKARRGLSASDLINLNADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY
                     ANTFRLHWLAVKREHMIWRCDNEMDIHQLLTAAMDPQEFARFSQVWQENGLDHNWLPL
                     PVHPWQWQQKIATDFIADFAEGRMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPL
                     TIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVILGEPAAGYVSHEGYA
                     ALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLD
                     AETWLTQLFRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLV
                     KEEFPEMDSLPQEVRDVTSRLSADYLIHDLQTGHFVTVLRFISPLMVRLGVPERRFYQ
                     LLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRMLPNYLED
                     LQNPLWLVTQEYES"
     gene            4427..5704
                     /gene="iucD"
                     /locus_tag="IRB70_004444"
     CDS             4427..5704
                     /gene="iucD"
                     /locus_tag="IRB70_004444"
                     /EC_number="1.14.13.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001354579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADPH-dependent L-lysine N(6)-monooxygenase"
                     /protein_id="HBC0634282.1"
                     /translation="MKKSVDFIGVGTGPFNLSIAALSHQIEELDCLFFDEHPHFSWHP
                     GMLVPDCHMQTVFLKDLVSAVAPTNPYSFVNYLVKHKKFYRFLTSRLRTVSREEFSDY
                     LRWAAEDMNNLYFSHTVENIDFDKKRRLFLVQTSQGEYFARNICLGTGKQPYLPPCVK
                     HMTQSCFHASEMNLRRPDLSGKRITVVGGGQSGADLFLNALRGEWGEAAEINWVSRRN
                     NFNALDEAAFADEYFTPEYISGFSGLEEDIRHQLLDEQKMTSDGITADSLLTIYRELY
                     HRFEVLRKPRNIRLLPSRSVTTLESSGPGWKLLMEHHLDQGRESLESDVVIFATGYRS
                     ALPQILPSLMPLITMHDKNTFKVRDDFTLEWSGPKENNIFVVNASMQTHGIAEPQLSL
                     MAWRSARILNRVMGRDLFDLSMPPALIQWRSGT"
     gene            5786..7987
                     /gene="iutA"
                     /locus_tag="IRB70_004445"
     CDS             5786..7987
                     /gene="iutA"
                     /locus_tag="IRB70_004445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004213924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferric aerobactin receptor IutA"
                     /protein_id="HBC0634283.1"
                     /translation="MMISKKYTLWALNPLLLTMMAPAVAQQTDDETFVVSANRSNRTV
                     AEMAQTTWVIENAELEQQIQGGKELKDALAQLIPGLDVSSRSRTNYGMNVRGRPLVVL
                     VDGVRLNSSRTDSRQLDSIDPFNIDHIEVISGATSLYGGGSTGGLINIVTKKGQPETM
                     MEFEAGTKSGFSSSKDHDERIAGAVSGGNEHISGRLSVAYQKFGGWFDGNGDATLLDN
                     TQTGLQYSDRLDIMGTGTLNIDESRQLQLITQYYKSQGDDDYGLNLGKGFSAIRGTST
                     PFVSNGLNSDRIPGTERHLISLQYSDSAFLGQELVGQVYYRDESLRFYPFPTVNANKQ
                     VTAFSSSQQDTDQYGMKLTLNSKPMDGWQITWGLDADHERFTSNQMFFDLAQASASGG
                     LNNKKIYTTGRYPSYDITNLAAFLQSGYDINNLFTLNGGVRYQYTENKIDDFIGYAQQ
                     RQIAAGKATSADAIPGGSVDYDNFLFNAGLLMHITERQQAWLNFSQGVELPDPGKYYG
                     RGIYGAAVNGHLPLTKSVNVSDSKLEGVKVDSYELGWRFTGNNLRTQIAAYYSISDKS
                     VVANKDLTISVVDDKRRIYGVEGAVDYLIPDTDWSTGVNFNVLKTESKVNGTWQKYDV
                     KTASPSKATAYIGWAPDPWSLRVQSTTSFDVSDAQGYKVDGYTTVDLLGSYQLPVGTL
                     SFSIENLFDRDYTTVWGQRAPLYYSPGYGPASLYDYKGRGRTFGLNYSVLF"
BASE COUNT         1946 a         2179 c         2209 g         1975 t
ORIGIN      
        1 aggagctgtt tgattatgat cctgccctct gaaaaatccg ccacagatgt ggctgcgcag
       61 tgcttcctga atgccttgat tcgtgaaacc aaagactggc aactggcgga atacccgcca
      121 gacgaattga ttatcccgct ggacgaacag aagtcgctcc atttcagagt ggcttatttc
      181 tccccaaccc agcatcaccg ctttgcattt cctgctcatc tggtcacggc atcaggcagt
      241 tatcctgtcg actttaccac tctctcccgg cttattattg ataagctccg gcatcaactt
      301 tttctgccag ttcccctctg cgaaactttc caccagcgcg tgctggaaag ctacgcccat
      361 acgcaacaga caattgatgc ccgccatgac tgggccatcc tgcgtgaaaa agcgttgaat
      421 tttggcgagg ctgagcaggc actgctgaca ggacacgctt tccaccctgc acctaagtct
      481 catgaaccgt ttaaccgcca ggaagctgaa cgatacctgc ctgacatggc acctcacttc
      541 ccgctgcggt ggttttcggt ggataaaacg caaatcgctg gtgaaagtct gcatcttaac
      601 cttcaacagc ggttgacgcg atttgccgca gaaaatgcgc cccagttact caacgaatta
      661 agtgacaatc aatggctgtt cccgctgcac ccgtggcagg gagaatatct tttgcagcaa
      721 gtgtggtgcc aggcactttt tgctaaagga cttatcagag acttaggcga ggccggcacg
      781 tcgtggctgc cgaccacctc ttcccgctcc ctctactgtg ctaccagccg cgatatgatc
      841 aagttctccc tgagcgttcg gctgaccaac tccgtccgta ctctgtctgt gaaagaggtg
      901 gagcgaggaa tgcgcctggc acgtctgacg caaaccgacg gctggcagat gctacaggcc
      961 cgcttcccta ctttccgggt aatgcaggag gacggctggg ccgggctgcg cgatcttaac
     1021 ggcaacatca tgcaggaaag tttgttttcc ctgcgtgaaa acctgctgct ggagcagccg
     1081 caaagccaga ccaacgttct ggtttccctg actcaggccg caccggatgg cggtgattcg
     1141 ctgctggttt cggcggtaaa acgcctgagc gatcgcctcg gtatcactgt gcaacaggcc
     1201 gcccacgcat gggtcgatgc ttactgtcag caggtgctga agcctctgtt tacggctgaa
     1261 gcggattacg gcctggtgct gctggcgcat cagcaaaata ttcttgtgca gatgcttggg
     1321 gatctgccgg tcggatttat ttaccgtgac tgccagggca gcgcgtttat gcctcacgcg
     1381 acagagtggc tcgataccat tgacgaggcg caggcggaaa atattttcac ccgtgagcag
     1441 ttgctgcgct atttccctta ttacctgctg gttaactcca cttttgccgt aactgctgcg
     1501 ctgggtgctg ccgggctgga cagcgaagcg aatctgatgg ctcgtgtacg aacattgctg
     1561 gctgaagtgc gtgaccaggt gactcataaa acctgtctca actatgttct ggaaagtccg
     1621 tactggaacg taaaaggtaa ctttttctgt tatctgaacg atcataacga gaacaccatc
     1681 gttgaccctt cggtgatcta ttttgatttc gctaacccgc tgcaggctca ggaggtctga
     1741 atgtctgggg caaacattgt tcacagcgga tatggactgc gctgtgaaaa actcgacaag
     1801 cctctgaatc ttggctgggg gctggacaat agcgcggtgt tgcactggcc cggggagctg
     1861 ccaacagggt ggctgtgcga cgcgctggat cagatattta tcgccgcacc acaactttca
     1921 gcagtggttc ttccctggtc cgaatggtgt gaggagccac aggcgctgac gcttttcgga
     1981 caggtacaaa gcgacattat ccatcgttcc gctttctggc agttaccgtt atggctgagt
     2041 tctccggcaa accgggcctc cggtgaaatg gtttttgatg cagagcgtga gatttatttc
     2101 ccgcagcgcc ccccccgtcc gcagggtgaa gtttatcgtc gttacgatcc acgcattcgc
     2161 aggatgctga gtttccgcat tgccgatccc gtttctgatg cagaacgttt cactcgctgg
     2221 atgaacgatc cgcgcgttga gtatttctgg gagcaaagtg gctcactgga ggtacagatc
     2281 gcctatctgg aacgccagct caccagtaaa catgcattcc cgctgattgg ttgtttcgac
     2341 gatcggccgt tcagttattt cgaaatctac tgggcggcgg aagaccgcat tggtcgccac
     2401 tattcgtggc agccctttga ccgtggcctg catctgctgg ttggtgaaca gcaatggcgc
     2461 ggagcccact atgtgcaaag ctggctgcgc ggggtgacac attacctgct gctgaatgag
     2521 ccacgtacgc agcgcacagt actggagcca cgcaccgata accagcgcct gttccgccat
     2581 cttgagcctg cgggataccg gacaattaaa gagttcgact tcccacataa acgctcgcgc
     2641 atggtgatgg cggatcgtca tcacttcttc acggaggtcg gtctgtaatg aatcacaaag
     2701 actgggattt ggtcaaccgc cgcctggtgg caaaaatgtt gtctgagctg gagtatgagc
     2761 aggttttcca cgcggaatct cagggcgatg accgctactg cattaacctg ccgggagcac
     2821 aatggcgctt catcgctgaa cgtggtatct ggggctggct ctggattgat gctcaaactc
     2881 tgcgctgcgc ggacgagcca gtactggctc agacgctgct gatgcagcta aagcaggtac
     2941 tgtcaatgag cgatgcaacc gttgctgagc atatgcagga tttgtatgcc acgctgctgg
     3001 gcgacctgca actactgaaa gcccgtcgcg ggctgagcgc cagtgacctg attaatctta
     3061 atgccgaccg cctgcaatgc ctgctgagcg gtcatcctaa attcgttttt aataaaggtc
     3121 gccgtggctg gggtaaagag gcgctggaac gatatgcgcc agagtatgcc aacaccttca
     3181 gactgcactg gctggcggta aaacgtgaac atatgatctg gcgctgtgat aacgagatgg
     3241 atattcatca gttgttgacg gccgcaatgg atccgcagga gtttgcccgc ttcagtcagg
     3301 tctggcagga aaacggactg gatcataact ggctgccgct gccggtacat ccgtggcagt
     3361 ggcagcaaaa aatcgctacc gacttcatcg ctgattttgc cgaaggcagg atggtgtctc
     3421 tcggcgagtt tggcgaccag tggctcgccc agcagtcgct gcgtaccctg accaacgcca
     3481 gtcgccgggg cgggctggat atcaagctgc cgctgaccat ctacaacacc tcatgctacc
     3541 gggggatccc tggcagatac atcgctgccg gaccactggc ttcacgctgg ctacaacagg
     3601 tttttgcgac cgacgccacc ctggtgcaaa gcggcgcagt gatacttggt gaaccggctg
     3661 caggctatgt ctcccatgaa ggctatgccg cgcttgcccg ggctccctat cgctaccagg
     3721 aaatgcttgg tgttatctgg cgggagaatc cgtgccgctg gctgaaaccg gatgaaagtc
     3781 cggttctgat ggcaacactg atggagtgcg acgaaaacaa tcagccgctg gcaggcgcat
     3841 atatagaccg ctccgggctg gacgctgaaa cctggcttac gcaactgttc cgggtggtcg
     3901 tggttcctct gtatcacctg ctttgccgct acggtgtcgc gcttattgca catggacaaa
     3961 atataactct cgccatgaaa gagggggttc cacagcgtgt tctgctgaaa gacttccagg
     4021 gcgatatgcg actggtgaaa gaagagttcc ccgaaatgga ctctttgcct caggaggttc
     4081 gtgatgttac atcccgcctg agtgcggact acttaatcca tgatttgcag acgggtcact
     4141 tcgtgacagt actgcgtttt atttcgccac tgatggttcg tcttggcgta cctgaaaggc
     4201 gattttatca actgctggca gcagtgttga gtgattacat gaaaaaacat ccacaaatgt
     4261 cagagcgttt tgcgcttttc tcacttttca ggccacaaat cattcgcgtg gtgctgaacc
     4321 cggtaaaact gacctggcct gatctggatg gcggcagccg catgctgccg aattaccttg
     4381 aggatctgca aaatccgctg tggctggtaa ctcaggaata tgaatcatga aaaaaagtgt
     4441 cgattttatt ggtgtaggga cagggccatt taatctcagc attgctgcgt tgtcacatca
     4501 gatcgaagaa ctggactgtc tcttctttga tgaacatcct catttttcct ggcatccggg
     4561 tatgctggta ccggattgtc atatgcagac cgtctttctg aaagatctgg tcagtgctgt
     4621 tgcacctaca aatccctaca gttttgttaa ctatctggtg aagcacaaaa agttctatcg
     4681 cttccttaca agcagactac gtacagtatc ccgtgaagag ttttctgact acctccgctg
     4741 ggctgctgaa gatatgaata acctgtattt cagtcatacc gttgaaaaca ttgatttcga
     4801 taaaaaacgt cgattgtttc tggtgcaaac cagccaggga gaatattttg cccgcaatat
     4861 ctgccttggt acaggaaaac aaccttattt accaccctgt gtgaagcata tgacacaatc
     4921 ctgtttccat gccagtgaaa tgaatcttcg tcggccggac cttagtggaa aacggataac
     4981 cgtggttggt ggaggacaga gtggtgcaga cctgttcctt aatgcattac gcggggaatg
     5041 gggagaagcg gcggaaataa actgggtctc ccggcgtaat aattttaacg cactggatga
     5101 ggctgctttt gctgatgagt attttacacc tgaatatatt tcaggcttct ccggactgga
     5161 ggaagatatt cgccatcagt tactggatga gcagaaaatg acatcggatg gcatcactgc
     5221 cgattcttta ctgaccattt atcgtgagtt gtaccaccgt tttgaagttc tgagaaaacc
     5281 aagaaatatc cgtctgctac ccagccgctc ggtaacaact ctggaaagta gtggtcctgg
     5341 ctggaagttg ctgatggagc atcatctgga tcagggcagg gagagcctgg aaagtgatgt
     5401 ggtgattttc gccacaggtt accgttctgc gttgccacaa atacttccct cactgatgcc
     5461 cctgatcacc atgcacgata agaacacctt taaagtgcgt gatgacttca ctctggaatg
     5521 gagtggcccg aaagagaaca acatcttcgt ggtcaacgcc agtatgcaaa cccatggcat
     5581 cgccgaaccc cagctcagcc tgatggcatg gagatctgca cgtattctta atcgcgtaat
     5641 gggacgtgat ttattcgatc tcagtatgcc gcccgccctg attcagtggc gcagcggcac
     5701 ctagggaaaa cgcagccgga ggctgcttct ttaactcgct acacagcatc tttgggctga
     5761 ttttttccgc ccgtatggag gaataatgat gataagcaaa aagtatacgc tttgggctct
     5821 caacccactg cttcttacca tgatggcgcc agcagtcgct caacaaaccg atgatgaaac
     5881 gttcgtggtg tctgccaacc gcagcaatcg caccgtagcg gagatggcgc aaaccacctg
     5941 ggttatcgaa aacgccgaac tggaacagca gattcagggc ggcaaagagc ttaaagacgc
     6001 actggctcag ctgatccctg gccttgacgt cagcagccgg agccgcacca actacggtat
     6061 gaatgtgcgt ggccgcccgc tggtcgtgct ggttgacggc gtgcgtctca actcttcacg
     6121 taccgacagc cgacaactgg actctataga tccttttaat atcgaccata ttgaagtgat
     6181 ctccggtgcg acgtccctgt acggcggcgg cagtaccggt ggcctgatca acatcgtgac
     6241 caaaaaaggc cagccggaaa ccatgatgga gtttgaggct ggcaccaaaa gtggctttag
     6301 cagcagtaaa gatcacgatg aacgcattgc cggagctgtc tccggcggaa atgagcatat
     6361 ctccggacgt ctttccgtgg catatcagaa atttggcggc tggtttgacg gtaacggcga
     6421 tgccaccttg cttgataaca cccagaccgg cctgcagtac tccgatcggc tggacatcat
     6481 gggaactggt acgctgaaca tcgatgaatc ccggcagctt cagttgatca cacagtacta
     6541 taaaagccag ggcgacgacg attacgggct taatctcggg aaaggcttct ctgccatcag
     6601 agggaccagc acgccattcg tcagtaacgg gctgaattcc gaccgtattc ccggcactga
     6661 gcggcatttg atcagcctgc agtactctga cagcgctttt ctgggacagg agctggtcgg
     6721 tcaggtttac taccgcgatg agtcgttgcg attctacccg ttcccgacgg taaatgcgaa
     6781 caaacaggtg acggctttct cttcgtcaca gcaggacacc gaccagtacg gcatgaaact
     6841 gactctgaac agcaaaccga tggacggctg gcaaatcacc tgggggctgg atgctgatca
     6901 tgagcgcttt acctccaacc agatgttctt cgacctggct caggcaagcg cttccggagg
     6961 gctgaacaac aagaagattt acaccaccgg gcgctatccg tcgtatgaca tcaccaacct
     7021 ggcggccttc ctgcaatcag gctatgacat caataatctc tttaccctca acggtggcgt
     7081 acgctatcag tacactgaaa acaagattga tgatttcatc ggctacgcgc agcaacggca
     7141 gattgccgcc gggaaggcta catccgccga cgccattcct ggcggctcag tcgattacga
     7201 caacttcctg ttcaacgccg gtctgctgat gcacatcacc gaacgccagc aggcatggct
     7261 caacttctcc cagggcgtgg agctgccgga cccgggtaaa tactatggtc gcggcatcta
     7321 tggtgctgca gtgaacggcc atcttcctct aacaaagagt gtgaacgtca gcgacagcaa
     7381 gctggaaggc gtgaaagtcg attcttatga gctgggctgg cgctttactg gcaataatct
     7441 gcgtacccaa atcgcggcct actattcgat ttctgataag agcgtggtgg cgaataaaga
     7501 tctgaccatc agcgtggtgg acgacaaacg ccgtatttac ggcgtggaag gtgcggtgga
     7561 ctacctgatt cctgatactg actggagtac cggagtgaac ttcaacgtgc tgaaaactga
     7621 gtcgaaagtg aacggtacct ggcagaaata cgatgtgaag acagcaagcc catcaaaagc
     7681 gacagcctac attggctggg caccggaccc gtggagtctg cgcgtgcaga gcaccacctc
     7741 ctttgacgtg agcgacgcgc agggctacaa ggtcgatggc tataccaccg tggatctgct
     7801 cggcagttat cagcttccgg tgggtacact cagcttcagc attgaaaacc tcttcgaccg
     7861 tgactacacc actgtctggg ggcagcgtgc accactgtac tacagcccgg gttacggccc
     7921 agcgtcactg tacgactaca aaggcagggg ccgaaccttt ggtctgaact actctgtgct
     7981 gttctgaccg gtattccttt acaacaaagg tacgctgata tcaacatggc cgctgacagc
     8041 caagttgata tcatataata cacgacataa tctgtagtca gggaggatag actctttact
     8101 gactacagat tatgtcgtgt tccgtgctca tttcctcaaa aaaatacaag aaaagaatta
     8161 gtattctaac aaaaagtgaa ataaattgta tcaaactccc tcttttaatc ctgttgagta
     8221 aatcagcttt tgcaatagga ttgaaagagt gtaagtggaa tctcttccgg atactcgtta
     8281 ccaccgtggc tagaatatct acggctgcg
//
LOCUS       DADXDL010000140         8256 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.140, whole genome shotgun sequence.
ACCESSION   DADXDL010000140 DADXDL010000000
VERSION     DADXDL010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8256
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.140"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..192)
                     /locus_tag="IRB70_004446"
     CDS             complement(<1..192)
                     /locus_tag="IRB70_004446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634284.1"
                     /translation="MLQSSADKACNVLVKKVRYLNDVRKITKMMNGKLIYSWLVWPCS
                     EFFSLNYKLTKRIYFITFIY"
     gene            270..1364
                     /gene="ddlA"
                     /locus_tag="IRB70_004447"
     CDS             270..1364
                     /gene="ddlA"
                     /locus_tag="IRB70_004447"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBC0634285.1"
                     /translation="MEKLRVGIVFGGKSAEHEVSLQSAKNIVDAIDKSRFDVVLLGID
                     KQGQWHVSDASNYLLNADDPAHIALRPSATSLAQVPGKHEHQLIDAQNGQPLPTVDVI
                     FPIVHGTLGEDGSLQGMLRVANLPFVGSDVLASAACMDKDVTKRLLRDAGLNIAPFIT
                     LTRANRHNISFAEVESKLGLPLFVKPANQGSSVGVSKVTSEEQYAIAVDLAFEFDHKV
                     IVEQGIKGREIECAVLGNDNPQASTCGEIVLTSDFYAYDTKYIDEDGAKVVVPAAIAP
                     EINDKIRAIAVQAYQTLGCAGMARVDVFLTPENEVVINEINTLPGFTNISMYPKLWQA
                     SGLGYTDLITRLIELALERHAADNALKTTM"
     gene            complement(1388..1600)
                     /locus_tag="IRB70_004448"
     CDS             complement(1388..1600)
                     /locus_tag="IRB70_004448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414914.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2754 domain-containing protein"
                     /protein_id="HBC0634286.1"
                     /translation="MNLPVKIRRDWHYYAFAIGLIFILNGVVGLLGFEAKGWQTYAVG
                     LVTWVISFWLAGLIIRRRDEETENAQ"
     gene            1860..2168
                     /locus_tag="IRB70_004449"
     CDS             1860..2168
                     /locus_tag="IRB70_004449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiY family protein"
                     /protein_id="HBC0634287.1"
                     /translation="MADFTLSKSLFSGKYRNASSTPGNIAYALFVLFCFWAGAQLLNL
                     LVHAPGVYERLMQVQETGRPRVEIGLGVGTIFGLIPFLVGCLIFAVVALWLHWRHRRQ
                     "
     gene            complement(2226..3320)
                     /gene="yaiW"
                     /locus_tag="IRB70_004450"
     CDS             complement(2226..3320)
                     /gene="yaiW"
                     /locus_tag="IRB70_004450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="surface-exposed outer membrane lipoprotein YaiW"
                     /protein_id="HBC0634288.1"
                     /translation="MSRVNHLSSLSLLAVLVLAGCSSQAPQPLKKGEKAIDVASVVRQ
                     KMPASVKDRDAWAKDLATTFESQGLAPTLENVCSVLAVAQQESNYQADPAVPGLSKIA
                     WQEIDRRAERMHIPAFLVHTALKIKSPNGKSYSERLDSVRTEKQLSAIFDDLISMVPM
                     GQTLFGSLNPVRTGGPMQVSIAFAEQHTKGYPWKMDGTVRQEVFSRRGGLWFGTYHLL
                     NYPASYSAPIYRFADFNAGWYASRNAAFQNAVSKVSGVKLALDGDLIRYDSKEPGKTE
                     LATRKLAGKLGMSDSEIRRQLEKGDSFSFEETALYKKVYQLAEAKTGKSLPREMLPGI
                     QLESPKITRNLTTAWFAKRVDERRARCMKQ"
     gene            complement(3333..4553)
                     /gene="sbmA"
                     /locus_tag="IRB70_004451"
     CDS             complement(3333..4553)
                     /gene="sbmA"
                     /locus_tag="IRB70_004451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide antibiotic transporter SbmA"
                     /protein_id="HBC0634289.1"
                     /translation="MFKSFFPKPGTFFLSAFVWALIAVIFWQAGGGDWVARITGASGQ
                     IPISAARFWSLDFLIFYAYYIVCVGLFALFWFIYSPHRWQYWSILGTALIIFVTWFLV
                     EVGVAVNAWYAPFYDLIQTALSSPHKVTIEQFYREVGVFLGIALIAVVISVLNNFFVS
                     HYVFRWRTAMNEYYMANWQQLRHIEGAAQRVQEDTMRFASTLENMGVSFINAIMTLIA
                     FLPVLVTLSAHVPELPIVGHIPYGLVIAAIVWSLMGTGLLAVVGIKLPGLEFKNQRVE
                     AAYRKELVYGEDDATRATPPTVRELFSAVRKNYFRLYFHYMYFNIARILYLQVDNVFG
                     LFLLFPSIVAGTITLGLMTQITNVFGQVRGAFQYLINSWTTLVELMSIYKRLRSFEHE
                     LDGDKIQEVTHTLS"
     gene            4905..6062
                     /gene="ampH"
                     /locus_tag="IRB70_004452"
     CDS             4905..6062
                     /gene="ampH"
                     /locus_tag="IRB70_004452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine-
                     carboxypeptidase/endopeptidase AmpH"
                     /protein_id="HBC0634290.1"
                     /translation="MKRSLLFSAVLCAASLTSVHAAQPITEPEFASDIVDRYADHIFY
                     GSGATGMALVVIDGNQRVFRSYGETRPGNNVRPQLDSVVRIASLTKLMTSEMLVKLLD
                     QGTVKLNDPLSKYAPPGARVPTYNGTPITLVNLATHTSALPREQPGGAAHRPVFVWPT
                     REQRWKYLSTAKLKAAPGSQAAYSNLAFDLLADALANASGKPYTQLFEEQITRPLGMK
                     DTTYTPSPDQCRRLMVAERGASPCNNTLAAIGSGGVYSTPGDMMRWMQQYLSSDFYQR
                     SNQADRMQTLIYQRAQFTKVIGMDVPGKADALGLGWVYMAPKEGRPGIIQKTGGGGGF
                     ITYMAMIPQKNIGAFVVVTRSPLTRFKNMSDGINDLVTELSGNKPLVIPAS"
     gene            complement(6063..6686)
                     /gene="iprA"
                     /locus_tag="IRB70_004453"
     CDS             complement(6063..6686)
                     /gene="iprA"
                     /locus_tag="IRB70_004453"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrogen peroxide resistance inhibitor IprA"
                     /protein_id="HBC0634291.1"
                     /translation="MLSVVKPLQEFGKLDKCLSRYGTRFEFNNEKQVIFSSDVNSEDT
                     FVILEGVISLRREENVLIGITQAPYIMGLADGLMKNDIPYKLISEGNCTGYHLPAKQT
                     ITLIEQNQLWRDAFYWLAWQNRILELRDVQLIGHNSYEQIRATLLSMIDWNEELRSRI
                     GVMNYIHQRTRISRSVVAEVLAALRKGGYIEMNKGKLVAINRLPSEY"
     gene            complement(6772..>8256)
                     /locus_tag="IRB70_004454"
     CDS             complement(6772..>8256)
                     /locus_tag="IRB70_004454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBC0634292.1"
                     /translation="WLSGDSGGQSTALYANNIKVTNDGILDVGNTAANALQVDTLNLT
                     STTDTSGNIHAGVFNIESNRFVLDADLTNDRTNDTTKSNYGYGLIAMNSDGHLTINGN
                     GDNDNTASIEAGQNEVDNNGDHVAAATGNYKVRIDNATGAGSIADYNGNELIYVNDKN
                     SNATFSAANKADLGAYTYQAEQRGNTVVLQQMELTDYANMALSIPSANTNIWNLEQDT
                     VGTRLTNSRHGLADNGGAWVSYFGGNFNGDNGTINYDQDVNGIMVGVDTKIDGNNAKW
                     IVGAAAGFAKGDMNDRSGQVDQDSQTAYIYSSAHFANNVFVDGSLSYSHFNNDLSATM
                     SNGTYVDGSTNSDAWGFGLKAGYDFKLGDAGYVTPYGSVSGLFQSGDDYQLSNNMKVD
                     GQSYDSMRYELGVDAGYTFTYSEDQALTPYFKLAYVYDDSNNHNDVNGDSIDNGTEGS
                     AVRVGLGTQFSFTKNFSAYTDANYLGGGDVDQDWSANVGVKYTW"
BASE COUNT         2087 a         2087 c         2005 g         2077 t
ORIGIN      
        1 ataaataaaa gttatgaaat atattctctt cgttaactta taattaagag aaaaaaactc
       61 actgcatggc catacaagcc aggaataaat tagcttcccg ttcatcattt ttgtgatctt
      121 gcgcacatca ttgagataac gcactttctt caccagtacg ttgcacgctt tgtcagcaga
      181 agattgcaac attctgtcag aaggccgcga atcccccgtt ttgtcgtggt aatgtatgca
      241 ctttgtgtta gacgggatag gtttttaaga tggaaaaact gcgggtagga atcgtttttg
      301 gtggtaaatc agcggaacat gaagtgtctc tgcaatcggc aaaaaacatt gtcgatgcca
      361 ttgataaaag tcgcttcgac gttgtgctgc tgggcattga taaacaaggg caatggcacg
      421 tcagcgatgc cagcaattat ctgctaaatg cagacgatcc tgcccatatt gcgttgcgcc
      481 cttcggcgac cagccttgcg caggtgcctg gtaaacatga acatcagctt atcgacgcgc
      541 aaaacggtca gccgttgccg acggtggatg tcattttccc gattgtccac ggtacgctgg
      601 gcgaagatgg ttccttgcag ggaatgctgc gggtcgccaa tttaccgttt gtaggttctg
      661 atgttctggc ttcagcggcc tgtatggata aagatgtcac caaacgtctg ctgcgcgatg
      721 ccgggctgaa cattgcgcca tttattaccc tgacgcgcgc taatcgtcac aacatcagtt
      781 ttgccgaagt ggagtctaaa ctggggttac cgctgtttgt aaaaccggct aatcagggct
      841 cttctgttgg tgtcagcaaa gtaaccagtg aagaacagta cgcaattgcc gtcgatctgg
      901 cgttcgagtt cgaccataaa gtgatcgttg agcaagggat caaaggtcgt gagatcgaat
      961 gcgcagttct gggcaacgac aatccgcaag ccagcacctg tggcgagatc gtactaacca
     1021 gcgattttta tgcctacgac accaagtaca ttgacgaaga tggcgcgaaa gtggttgttc
     1081 cggcagccat tgcgccagaa atcaacgata agatccgggc gattgccgtt caggcctatc
     1141 aaacgttggg atgcgcaggc atggcgcgtg tagacgtgtt tttaacccca gagaacgaag
     1201 tggtgatcaa cgagatcaac accctgcctg gcttcaccaa catcagtatg tatccgaagt
     1261 tgtggcaagc cagcggtctg ggttacaccg acctgatcac gcgtttgatt gagctggcgc
     1321 tggagcgtca cgctgcagat aacgcactga aaaccacaat gtaatattca aacgcccagt
     1381 aatattctta ttgggcgttt tcagtttctt catcgcgacg acgaataatc aaccccgcca
     1441 gccagaaact aatcacccac gtcaccagac cgacggcata ggtctgccaa ccttttgctt
     1501 caaatcccag taaccccacc acgccattaa gaatgaatat aaggccaatg gcgaacgcat
     1561 agtagtgcca gtcacggcgg atttttacag gcaagttcat ggcagctccg ttaacgaaaa
     1621 acaacatctt tgcatattct gtaacaactg tctgtggggt agacaacact ttcgcatttg
     1681 ttaataaatt taacttaagg ttgccatttt gtgactcaca acgaagattc acgcttcggg
     1741 aatattccca acatcaattt accatgattc tgatattgac aatctaaatg acctgtcaga
     1801 cttgccataa gccgctggta tcacaccaga agagaagcag atgacttccg gaggttttta
     1861 tggctgattt caccctgtca aaatcgctgt ttagcggaaa atatcgcaat gcctcttcaa
     1921 cgcctggcaa tattgcctat gcgttgtttg tgctgttttg cttttgggct ggggcgcaat
     1981 tgctgaacct gctagtgcat gcgcccggcg tctatgagcg cttaatgcag gtccaggaaa
     2041 caggtcgccc acgggtggaa attggtttag gtgtcggcac cattttcggg ctgatcccgt
     2101 ttttagttgg ctgcctcatt tttgcagtag tggcgctatg gctgcactgg cgacatcgcc
     2161 gccagtaaga tttacttgcc agataggacc taaaacgctt tatctggcat gacattcctg
     2221 tttgatcact gtttcataca acgcgcccgc cgttcgtcta cgcgcttcgc aaaccaggcc
     2281 gtagtcaggt tgcgggtgat tttcgggctt tccagttgaa tgccaggcaa catttcgcgg
     2341 ggtagtgatt tacccgtttt cgcttcggca agttgataaa ctttcttgta cagcgccgtc
     2401 tcctcaaaag agaagctgtc ccctttctct aactggcggc gaatttcact gtcgctcatc
     2461 cccagttttc ccgccagttt gcgcgttgcc agttcggttt tcccgggctc tttactgtcg
     2521 taacgaatta aatcaccgtc cagtgccagc ttcacgccgc tgaccttact gaccgcgttc
     2581 tgaaacgcgg cattacggct ggcgtaccag ccagcgttaa aatcagcaaa acggtatatc
     2641 ggcgcgctat agctggcggg ataattcagt aaatggtaag taccaaacca caacccgccg
     2701 cgacgactga agacttcctg acggactgta ccgtccattt tccacggata ccctttggta
     2761 tgctgttcgg caaaggcaat gctgacctgc atcggcccac cggtgcgcac cggattaagc
     2821 gaaccaaaca acgtctgccc cattggcacc atgctgatca gatcgtcaaa aatcgcgctc
     2881 aattgctttt cagtacgcac cgaatctaac cgttcgctat agcttttgcc gtttggcgat
     2941 ttgattttta gcgcggtatg caccagaaaa gcaggaatgt gcatccgttc agcacgacgg
     3001 tcaatctctt gccaggcgat cttgcttaag cccggaacgg ccggatctgc ctgataattt
     3061 gactcctgct gcgccaccgc cagcaccgag cagacgtttt ccagcgtcgg tgccagcccc
     3121 tgactttcaa acgtggtggc gagatctttc gcccaggcat cgcggtcttt cacgctcgca
     3181 ggcatcttct gccgcacgac gctcgccaca tctatcgctt tttcgccctt tttcaacggt
     3241 tgcggagcct gactactaca ccccgctaaa accagaaccg ccaacaatga cagcgaagat
     3301 agatgattga cgcgcgacat tacttctcct ttttagctca aggtatgggt tacttcctga
     3361 attttgtcac catccagctc atgttcaaag ctgcgcagac gtttgtagat agacatcaac
     3421 tcaaccagtg tggtccatga gttaatcagg tactggaaag ctccgcgaac ctgaccaaaa
     3481 acgttggtaa tctgcgtcat caggccgagc gtaatcgtac cggcaacaat tgacggaaac
     3541 agcaagaaca aaccgaaaac gttatcgacc tgcaaataga gaatgcgggc gatattgaaa
     3601 tacatatagt gaaaatagag gcggaaatag tttttccgta cggcgctaaa aagctcgcgt
     3661 accgtaggcg gcgtcgcgcg cgtggcatcg tcttcaccat aaaccagctc tttacggtag
     3721 gcagcctcta cacgctggtt tttaaactcc agccccggca gtttgatccc taccactgcc
     3781 agtaatccgg tccccatcag cgaccagacg atagcggcaa tcaccagacc atacggaatg
     3841 tgcccgacaa tcggcagctc cggcacatgt gcggagagcg ttaccagcac cggcaggaag
     3901 gcgatcaacg tcatgatagc gttgataaag ctgacgccca tattctccag cgttgaagca
     3961 aaacgcatgg tgtcttcctg cacacgttgg gcggcacctt cgatatgacg cagttgttgc
     4021 cagttcgcca tgtaatattc gttcatcgct gtacgccagc ggaacacgta gtgactgaca
     4081 aagaagttgt tcagcacact gatcactacc gcgatcagcg caatccccag aaagacgccc
     4141 acttcgcggt aaaattgttc gatggtgact ttatgcggcg aacttagcgc ggtttgaatc
     4201 agatcataga acggcgcata ccaggcgttg acggcgaccc cgacttccac caaaaaccag
     4261 gtgacgaaga tgatcagtgc agtaccgagt attgaccagt attgccaacg atgcgggctg
     4321 tagataaacc agaacaatgc aaaaagtcct acgcaaacaa tgtagtaagc gtaaaaaatc
     4381 aggaaatcca acgaccagaa acgcgcggcg ctaatcggga tctgcccgga agcgccggtg
     4441 atacgcgcca cccagtcacc cccaccggct tgccagaaga taacggcaat caatgcccaa
     4501 acaaaggccg agagaaaaaa cgttcccggc tttgggaaaa aagacttaaa catatgcact
     4561 cctgctaact tcttatcgtt ttaacaactg ctgtgtatta accgcatgac cgctacaaag
     4621 cgtcagccaa atgaaaccgc ccattgtgac ccatagcaag gcgcttagtt cgccagcctg
     4681 accataagaa ttgtttcgac ggatttcaca aaccaaagat tgtttacata agcggattaa
     4741 cacgcgcagg atcacaaatg caggcattgg tgagcaggaa aaagatcgtg tttacgcgcc
     4801 gttacgtttt taacactatt attgcactaa ttcgcccttt gcaatccatc aatgagtagt
     4861 ataaatacgc tcagttacct tcattcaatt tatggacacc accgttgaaa cgtagtctgc
     4921 ttttttctgc cgtgctgtgt gcggcgtcat tgacctccgt ccatgcggcg cagccgatca
     4981 ctgaaccgga gtttgcctct gatattgtcg atcgttatgc cgatcatatt ttttacggca
     5041 gcggtgccac ggggatggcg ctggttgtta tcgacggtaa ccagcgcgtc tttcgcagtt
     5101 atggcgaaac gcgacctggt aataacgttc gcccgcagct ggattcggta gtgcgtattg
     5161 cttccctcac caagctaatg accagtgaga tgctggtgaa attgctcgac caggggaccg
     5221 tgaagttaaa cgatccgcta agtaaatatg ctccaccagg cgcacgtgtg ccgacttaca
     5281 atggcacgcc tattaccctg gtgaatctag caacccatac cagtgccctg ccccgtgaac
     5341 agccgggagg tgcggcacat cgtccagtgt ttgtctggcc aacgcgcgag caacgctgga
     5401 aatacctttc tacggcgaag ctgaaagccg cgccaggcag tcaggcggca tactctaacc
     5461 ttgcgttcga cctgctggca gatgcactgg cgaatgcttc cggcaagcct tatacccagt
     5521 tgtttgaaga gcagattacc cgtccattgg ggatgaaaga caccacctac accccctcgc
     5581 cggaccagtg ccgccgttta atggtggcag agcgcggtgc cagtccatgc aataacacgc
     5641 tggcggcaat tggcagcggc ggcgtctatt ccacgcctgg cgatatgatg cgctggatgc
     5701 agcagtattt gtcatctgat ttttatcagc gcagtaacca ggctgatcgc atgcagacgt
     5761 tgatttatca gcgagcgcag tttacgaaag tgattggcat ggatgtcccc ggcaaagcgg
     5821 atgcgcttgg tttaggctgg gtatatatgg ccccgaaaga gggtcgtcca gggattattc
     5881 agaagacagg cggtggtggc ggtttcatta cctatatggc gatgatcccg cagaagaata
     5941 ttggcgcgtt tgtggtggtc actcgttcgc cattgacgcg ctttaaaaat atgagcgatg
     6001 gcatcaatga cctggtgacc gaactgagcg ggaataaacc gttggtcatc cccgcgtcct
     6061 gattaatact ctgaaggcaa acggttgata gcgaccagtt tgcctttatt catttcgata
     6121 tagccgcctt tacgtaaagc agcgagaact tctgcgacga cagaacgcga tatgcgtgta
     6181 cgttgatgga tataattcat cacaccaata cgtgagcgta attcttcatt ccagtcaatc
     6241 attgataata aagttgcgcg gatttgttcg taggaattat gcccaatgag ctgtacgtca
     6301 cgtaattcca gaattctatt ttgccaggct aaccagtaaa aagcgtctcg ccagagttga
     6361 ttttgttcaa taagggtaat ggtttgtttg gctggcagat gatatcccgt acaatttcct
     6421 tctgatatta atttgtatgg tatatcgttt ttcattaaac catcagccag tcccataata
     6481 taaggagcct gggtaatacc gataagtacg ttttcttctc tacgcagaga gataacgccc
     6541 tctaaaataa cgaaagtatc ttcgctattg acatcacttg aaaatataac ttgcttttca
     6601 ttattaaact cgaagcgcgt gccatatctg gacaaacatt tatcgagctt accaaattcc
     6661 tgaagaggtt taactacaga taacatttgc gcgtcctttg cagtaatgcc cgtcaaatcc
     6721 ttgacgggca ttatttagat taaataacct atttcttcag agtgaagaat attaccaggt
     6781 atatttaaca cccacgttcg cggaccagtc ttgatctacg tcaccaccac cgaggtagtt
     6841 agcatcggta taggcgctga agttcttggt gaagctgaac tgagtaccca gaccaacacg
     6901 taccgcagac ccttcagtac cgttatcgat ggaatcaccg ttcacatcgt tatggttgtt
     6961 agagtcgtcg taaacgtaag ccagtttgaa gtacggagtc agagcctggt cttcgctgta
     7021 ggtgaaggta taacctgcat ctacacccag ttcataacgc atgctgtcgt aagactgacc
     7081 gtcaactttc atgttgttgc tcagctggta gtcatcacca gactggaaca gaccagaaac
     7141 gctgccgtaa ggagtcacgt aaccagcatc acccagtttg aagtcgtaac cggctttcaa
     7201 accgaagccc caagcgtcgg agttggtgct accgtcaacg taagtaccgt tgctcatggt
     7261 tgcagacagg tcgttgttga agtgagagta gctcaagcta ccgtcaacaa agacgttgtt
     7321 cgcgaagtga gcagaagagt agatgtaggc agtctggctg tcttgatcca cctgaccaga
     7381 acggtcattc atgtcacctt tagcgaagcc tgcagccgca ccgacgatcc acttagcgtt
     7441 gttaccgtca attttggtat caacaccgac catgatgccg ttaacatcct gatcatagtt
     7501 gatggtgcca ttgtcgccgt tgaagttacc accgaagtag cttacccatg cgccgccgtt
     7561 atcagccagg ccatgacgag agttggtcag acgagtacca acggtgtctt gttccaggtt
     7621 ccagatattg gtgttcgcag acgggatgct cagcgccatg ttagcgtagt cggtcagctc
     7681 catctgttgc agaacaacgg tgttaccgcg ctgttcagcc tgataggtgt atgcacccag
     7741 gtcagctttg ttagcagcag agaaggtcgc gttgctgttt ttgtcgttaa cgtagatcag
     7801 ctcgttgccg ttgtagtcag cgatagaacc agcaccagta gcgttgtcga tacgaacttt
     7861 gtagttaccg gttgcagctg caacatggtc accgttgtta tcaacttcgt tctgaccagc
     7921 ttcgatagaa gcagtgttgt cgttatcgcc gttaccgtta atggtcaggt gaccatcaga
     7981 gttcattgcg attaaaccat aaccgtagtt tgacttggta gtatcgttgg tacggtcgtt
     8041 ggtcaggtcg gcatcaagta cgaagcggtt gctttcgata ttgaacacac cagcgtgaat
     8101 gttaccactg gtatcagtag tgctggtcag gttcagagta tcaacctgca gagcattcgc
     8161 cgcagtgtta cctacatcca ggataccgtc gttagtcact ttgatgttgt tggcatacag
     8221 agcagtagac tggccccctg aatctccaga caacca
//
LOCUS       DADXDL010000141         8214 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.141, whole genome shotgun sequence.
ACCESSION   DADXDL010000141 DADXDL010000000
VERSION     DADXDL010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 8214)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8214)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8214
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.141"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..845)
                     /gene="ag43"
                     /locus_tag="IRB70_004455"
     CDS             complement(<1..845)
                     /gene="ag43"
                     /locus_tag="IRB70_004455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HBC0634293.1"
                     /translation="MKRHLNTCYRLVWNHITGAFVVASGLARARGKRGGVAVALSLAA
                     VTSLPVLAADIVVHPGETVNGGTLANHDNQIVFGTTNGMTISTGLEYGPDNEANTGGQ
                     WVQDGGTANKTTVTSGGLQRVNPGGSVSDTVISAGGGQSLQGRAVNTTLNGGEQWMHE
                     GAIATGTVINDKGWQVVKPGTVATDTVVNTGAEGGPDAENGDTGQFVRGDAVRTTINK
                     NGRQIVRAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASDTVVNSDGWQ
                     IVKNGG"
     gene            complement(1173..2045)
                     /locus_tag="IRB70_004456"
     CDS             complement(1173..2045)
                     /locus_tag="IRB70_004456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HBC0634294.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHILEHLRKLTRHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLSGHGHSMVITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQRVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSARTGWELDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRSQAREQFTGAVDRIFDTAESVCVASVVRTALRAVRDT
                     VVSVARAVWNWIFF"
     gene            3276..4760
                     /locus_tag="IRB70_004457"
     CDS             3276..4760
                     /locus_tag="IRB70_004457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001405821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3987 domain-containing protein"
                     /protein_id="HBC0634295.1"
                     /translation="MSFGQPCDEFPLSSLPPLIRDAVIEAQQITQAPLGLVAASALGA
                     VSLVCQNLIDVCRLNTLRGPVSLFFLTLAESGERKTAVDKLLMKPLYQQEMQLYSRYK
                     SELAVWKNKEELLKAQKKALLSKLNKELRKGADESETLRQLEVLQKNSAEEPVRYKFI
                     FNDATTAAIKNQLCGKWRSVGIMSDEAGIIFDGYTLSELPFINKMWDGSVLSVDRKNE
                     PEQMIENARMTLSLMVQPGLFDRYMERKGSVARDSGFLARCLISKPATTQGKRFINGA
                     VIPGGSLTAFHERLMELARGSIEKSSEDERYCLHFSPEAQKIFIEHYNVLEQDLSPSG
                     PLSPFRGHVSKKTENIARIAALFQYFSYGEGKISADIMTSAVVISSWYTDEYKKLFAL
                     PDESELQQKDAEELFDWLIEECRGECPPRVRKNYILQCGPGRFRNRKKLNALLNILES
                     QFRLSVVPEGKTMYVLLPQIASLKLSDVSGIFTSGYHYNKLRAK"
     gene            complement(5082..5684)
                     /locus_tag="IRB70_004458"
     CDS             complement(5082..5684)
                     /locus_tag="IRB70_004458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001590672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634296.1"
                     /translation="MKPQYQTRYELLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRTTPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNCLDDWTENLKRK
                     SEKELEEWIINRQKQSAALTDLMDQYVLLAYRTTVDDKRT"
     gene            complement(5771..5977)
                     /locus_tag="IRB70_004459"
     CDS             complement(5771..5977)
                     /locus_tag="IRB70_004459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HBC0634297.1"
                     /translation="MLTPVSLMDDQMVDMAFITQLTGLTDKWFYKLIKDGDFPAPIKM
                     GRSSRWLKSEVEAWLQARIAQSRP"
     gene            6736..6885
                     /locus_tag="IRB70_004460"
     CDS             6736..6885
                     /locus_tag="IRB70_004460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
                     /protein_id="HBC0634298.1"
                     /translation="MEKVISHTRYKLTSAELEAFNSVVDHWLAELTMNKLYDRVPASV
                     WKYVI"
     gene            7700..>8214
                     /locus_tag="IRB70_004461"
     CDS             7700..>8214
                     /locus_tag="IRB70_004461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HBC0634299.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLRFPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWAREFGECKGKKHYHLMLLVN
                     RDTWCRAGDYRAPGSLAGMIKQAWCSALGVDVGCHATLVHFPAWPAVWLERDDDTGFQ
                     QVLERADYLAK"
BASE COUNT         2050 a         1892 c         2129 g         2143 t
ORIGIN      
        1 cccccgtttt tgacaatctg ccagccgtca ctgttcacaa cagtgtcaga cgctgtaccg
       61 ccgttgtgca catactggta tcccccattc agcgtggtat ccagtgcgtg accatgtaca
      121 gtctggtcgc cgccggcata aaccacagtg gtatttgccg ttccttcagc tctcacaatc
      181 tggcgaccgt ttttattgat ggttgtgcgt acggcatccc cgcgaacaaa ctgcccggta
      241 tcaccgtttt ctgcatccgg tcccccttcc gccccggtat taacaacggt atccgttgcc
      301 actgtaccgg gcttgacgac ctgccagccc ttatcattaa tgacggttcc tgtggctatc
      361 gccccctcat gcatccactg ttcgccacca ttcagcgtgg tgttcactgc ccgtccctga
      421 aggctctgtc cgcctccggc actgataacc gtgtctgaga cacttccacc ggggttcact
      481 ctctgaagac caccactggt gacagtcgtt ttgttggctg ttccgccatc ctgtacccat
      541 tgcccgccgg tattggcctc gttatccggc ccatactcca gcccggtact gatggtcatt
      601 ccgttggtcg taccgaagac aatctggttg tcatgatttg ccagtgttcc gccgttcacg
      661 gtttctcccg ggtgcacaac gatgtcagca gccagcaccg ggagtgacgt gactgcggca
      721 agagacagtg caaccgccac accgccacgt ttaccccgtg cgcgggccag tccggaggca
      781 accacgaaag cgcccgtaat gtgattccat accagcctgt agcaggtatt cagatgtcgt
      841 ttcatcagct tttccttaga ttgagggtga ataaaaaagc cggtacccac aaacgtggat
      901 accggcaggt aaagggttac agtgccggag gtccggctgt gggagtttct gaattgtggt
      961 tctgttgttc cctgaatgtc tttctgtacg tatctgtgca tgttactgac aaaggttatt
     1021 attagcttat cgatcgatat aaacgatcga taaaatagat atcgatcgtt ttattctatt
     1081 attgagctat tgcacggaca agagagacag taacgaaaac agtgcttttg tgagcagact
     1141 cagagtcagg gagggcatca gtcacgacag gttcagaaga aaatccagtt ccataccgca
     1201 cgggcaacag agaccaccgt gtcacgaaca gcgcgcaggg ccgtacggac aacagaggca
     1261 acacagacgc tctccgctgt gtcaaatatc cggtccaccg caccggtaaa ctgttcacgg
     1321 gcctgagagc ggacagattc cgtgcgcagc tcgtcctgca gtcgggtcat caggggactg
     1381 gcggcatggt cgggaagcgc tgtcatgagc gcactgacca gcgtatccag ttcccagccg
     1441 gtgcgggccg atacggccac aaccggatgt acgggtcgga acagacggaa taccgcctcc
     1501 gttttttcgc gaatattctg tgcctgtgca ggagaaggct gaataccggc catatcccat
     1561 tcatggcagg gctccgtttt gtcggcctgc gtcaccacaa acagtacccg ctgatgtccc
     1621 cggtgcagga tgtgtcgcca gaaatactca tccacagaca gggcacggtc atcggcttta
     1681 atcagccaca gtaccaggtc aagttcaggc agaatgtcac ggtacagggc ctcatactct
     1741 gcatccctgt cccggctctc gcccaccccg ggcaggtcag tgataaccat gctgtgaccg
     1801 tggccactca gacggaagcg ccgtacttcc cgggtgccgg cgtgaacatc actgaccggg
     1861 gtgacctccc cctgaaacag tgcattacag agtgaggatt taccggcccc gcttttaccc
     1921 ataatgccaa tcacgggttc gtgacgggtg agtttgcgca gatgttccag gatgtgacgg
     1981 gaaagcgagt aaggcaggga ggagagcggt ttttcaattg cctcaatggc atcagacgga
     2041 ttcatacatg tattcccggt gaaaaaagac aaaaccccgc gcaccggaaa ggtggcgggg
     2101 gattcacgga gataatatct gtctgaaatt gtttttaatc gatgggattg ttgcgtatta
     2161 acatgaagga gatcaggact tatccgttac tgggtgatct ccttccatga aaatacgccg
     2221 ttattgttaa acagcaggct gatttctccg taaaggggaa aatatttatc ggctgcatga
     2281 ttatcaggtg tgtctgtgtt tactgctgtg agtatttttc agtgtattgt gggggagatg
     2341 tcagtgggag atattaaatt tacatttata attatcttac ttcttctgtg tgttttttat
     2401 aagagtgcac acgtaatgat atctgttgat accatgtggt taagtgtttc ccttcctggt
     2461 catgcgtaat gattaaatgc ttttgtgaca ccattcttcc ggtctgaata tttatcccgt
     2521 tcttttttat ttgtgcagtg atactgtcgg aagagaattc agtaatgtga ggtgtcctgg
     2581 tcaggataat atctgctgag atattattag ttgagtgtgt ttttactgag caaaagctgg
     2641 cttttaattc ctgtactgaa acactgtcgc tcgtccgggg ttaactgaaa ctggatgatg
     2701 atgtaaaatg aaggctgttt ttgtgtttgt cgaagaagtg ttattttaat ccattctcat
     2761 cattggctgg cgattataca gaagtatttg aagaaaaaat ggtgcatttt atctgcgtca
     2821 gcagggagga agtattttat tgatgtatca gtattaaatg ttttttgtta tttataaata
     2881 tgtcatcctg tccatagaat attgtactca gcattcagtg caggaactgt agtcttcttt
     2941 attttattct tcttcaggag gggggggatt cctgaaggcg ttattcccgg tgttctgttt
     3001 atgattcatc ccggcaggaa accggtatct gcaatacccg ggatgatgct ttttgttcgt
     3061 acgtggttgt gtaaaatttg aatagtggat gtgctctgaa gggaaggagg ggacacacag
     3121 attcattttg tctttcttca gcagcaaaac acactgtggt tattatttaa ccattaaatc
     3181 aacaaaaatt tttacctcat attgatttga ctgctatttt tgctattaat agccagaatt
     3241 gcagtgcttt tatatctgtg tatagtgagg ttactatgtc attcggtcag ccttgtgatg
     3301 agtttcccct gagttcgctg cctccactca ttcgtgatgc cgttattgaa gctcagcaaa
     3361 ttacgcaggc tccccttggg cttgtggcag cgtctgccct gggcgctgtt tcacttgtct
     3421 gccagaatct gattgatgtc tgcagactga atacactgcg ggggccggtc tctctttttt
     3481 tcctgacgct tgccgagtcc ggagaacgaa aaaccgcagt ggacaaatta ttaatgaagc
     3541 ccctgtacca gcaggagatg cagttatatt ccagatacaa aagtgaactg gctgtctgga
     3601 aaaacaagga agagctttta aaggctcaga aaaaagcatt gttgtcaaaa ctgaataaag
     3661 aactccgcaa aggcgcggat gagtcagaaa ccctcagaca actggaagta cttcagaaaa
     3721 acagtgcgga agaacctgtg aggtataaat tcatttttaa tgatgccacg actgcggcaa
     3781 ttaagaatca gctttgtggt aaatggcgtt cagtgggtat tatgtcagat gaagccggta
     3841 ttatatttga tggatatacc ctgtctgagt tgccttttat taacaaaatg tgggatggct
     3901 ctgtattgtc tgtggacaga aagaatgaac ccgaacagat gattgaaaat gccagaatga
     3961 cgttatccct catggtgcaa cccggtcttt ttgaccgata tatggagcga aaaggttctg
     4021 ttgccaggga cagtggtttt cttgcccgtt gtcttatcag taaacctgca accacgcagg
     4081 ggaaacgctt tattaacgga gctgtgattc cgggaggatc attaacggca tttcatgaac
     4141 gattaatgga actggccaga ggcagtattg aaaaatccag tgaggatgaa cggtattgtc
     4201 tgcatttttc gcctgaagcg caaaaaatat ttattgagca ctataatgtt ctggagcagg
     4261 atttatcccc ttccggaccc ttaagcccgt ttcggggaca tgtttcaaaa aaaacagaaa
     4321 acattgcaag aattgcagcg ttatttcagt atttcagcta tggtgaaggg aaaatctctg
     4381 ccgatatcat gacgtctgct gtcgtaataa gttcgtggta cacagatgaa tataaaaaat
     4441 tatttgcgtt acctgatgaa tctgaactgc agcagaagga cgccgaggag ctgttcgact
     4501 ggctcattga ggagtgccgc ggagaatgcc caccccgtgt caggaaaaat tatattctcc
     4561 agtgtggccc gggtcggttc agaaacagga aaaaactgaa cgcattgctg aacattcttg
     4621 aatctcagtt caggctttct gtcgtgccgg aaggaaaaac catgtatgtt ctgcttcccc
     4681 agatagccag tttaaagttg tctgatgtct ctggtatttt tacctcgggt tatcactaca
     4741 ataagctgag agcgaagtaa ccggtgagca gtttttctcc attatgcttc agacttagat
     4801 gattgattat tatggggatt tcatcaccga tattcagatg tatgaatatc ggtgatgaac
     4861 taaagctcag gagctgcgtg gtggtgatga atcaacaggc atataactga tacccgccgg
     4921 tcagaagttc cagcctgcga ctttcctgtc tgcgtgcccg cagtccggcg ttcaggtgca
     4981 gcgtgtgaca gaacgcacgg agagcgaaac ggcaggcaga caggccgttc agtcagccct
     5041 ggcaccctgc ccggatacca gcttccctga aacaactggc atcaggtgcg cttatcgtca
     5101 accgttgtgc ggtatgccag gagcacgtac tgatccatca gatccgtcag tgctgcgctc
     5161 tgcttctgac ggttgatgat ccattcctcc agctcttttt ctgatttccg tttcagattc
     5221 tccgtccagt cgtcaaggca gtttccggtc attaaatcaa gccagcaaag ccagaccagt
     5281 ttgaggcgca actccgtgcc accaaactga cggaagaggc tgatcagttt atttgccagc
     5341 gaacgctgcc tcagacgttc acattcagac aggagaatgc cttccagcat cggatgatga
     5401 accagcagat gttcactggt gcataaattc actatcagat catcatccag gggcggcgtg
     5461 gtccgtttgt ccggaccata aatcagccgg tgcagactct ggggtacgat ggcaatctcc
     5521 ggtttttcac cattgaatga cacccacccg ggcgtcagat tatggaagta gtagatattc
     5581 ggatgacaca cgccccagga tacggcgtgc cgggtgaagc cggtcagcca tttctggtag
     5641 ctttcgtgga gcagctcgta acgggtctga tactgtggtt tcattttcat attcctcacg
     5701 ggggataaca ggcagcagaa cgccgccggc aggccggaga ctgcgtctgt tgcagatgaa
     5761 cggttaagaa ttacggacgg gactgtgcaa tacgcgcctg cagccaggct tccacttcgc
     5821 ttttcagcca tcgggagctg cggcccattt tgatgggcgc aggaaagtca ccatccttga
     5881 tgagtttgta aaaccactta tcggtcaggc cggtcagttg agtgataaat gccatgtcga
     5941 ccatctggtc atccatcagt gaaactgggg tgagcatgag aatgttcctc cggatgttgt
     6001 taaaccagcc ggtgtggtca tgaaaacaac gcaccacctt caccggcata acaaccgggg
     6061 agaaacgtaa aaaataatcg ggaatgtgac cgccaggaga taaacgggga ggttacggtg
     6121 gctgagccgt accggtatgc cgggtggttg ttacgaaacg atgcttccgc acgcgcgcgc
     6181 gataaagaag ggatgatttt cgtgaggaag aggggaaaac tggcgttctg ataattgcag
     6241 agttatttac ggggcggtta cgatggggca gaccgtgtcc ggtgggcagg cgacaggtat
     6301 caccgatggg ataagactgt ctgattggta ttataaatat ataagagaga tcaaacacat
     6361 gagatcaaat acatgagttc atatatgtga aataaacacg gtgagtgtga tcagtgggta
     6421 tgatgagaac gcagtagcaa cagactgcgc tatccctgat agctggcgta taacccgcgt
     6481 atataaaacg tatctgcaat gtacgtgaac agagtgcatt aagcatccgt ctgagcggta
     6541 aacatatccg acctggtgag tgacagtctg agagaccggt taagtggtgg ctcgggagta
     6601 atgagtttgg ggtgggtacc agaatgccag tctggcggta tgctgacagt atcacgttaa
     6661 ttgcagcata aagtgatgag aggctaatgg aagttaaaac caaagcagtt ccgtcgttgt
     6721 tcatcccggg agacgctgga aaaagtgatt tcccacacgc gttataaact tacctctgcg
     6781 gaactggaag ccttcaactc tgtggttgat cactggctgg cagaactgac aatgaacaag
     6841 ctttacgatc gtgttcccgc ttcagtctgg aaatatgtca tctgagcgtt cggtaatcac
     6901 aactgcatcg caccaggtgt tatccgcttt gtgattctta ttggctcttc tcaggttatt
     6961 aaaagctgaa tatgttcctg ttgtcgggaa ccaggataat accgggaacg ttaagcggta
     7021 tagcgacaac aaagaattcg aaatcaaaag ggaatggtgc cggaggcgtg ggcggtaata
     7081 ggctgatttt caggtattac cggcttacaa cgtgtggttg atattgaggg gctgtgagtt
     7141 tcgcgtattt gtcagaaacc cagatgagtt ttcctttatg ggacgaaata aggcagcggc
     7201 aatacctgga aaaatttaat atggtatgaa ggagaacctg tcggttacgc ttaatataca
     7261 cggtacactg tcagctcagg ggatacatga accgttatct caccagctac acagtataca
     7321 cacactgact gacgctgaca gtagtcagca ggaccacaat aatcagtgcc agcagtatgg
     7381 taacgatacg gtctgtattc cggtaatagc cgaaggggtc gacagaacca caatacgggc
     7441 aacatgtatt atgagtaatc gcgtttccac agtccctgca cttctttttg cgtatcacca
     7501 taactccctc ctcacagcct tacccgtaac cggtttttta cattaaaaaa acaacgctga
     7561 aaattcaacc gtcagtctgg agacgatagt tggggtatca cagagtgcct gagacagtgt
     7621 cctgccggag gtcacttcag ggactctgcg tattttttac gacgtggcta ttccgtatga
     7681 accatacgga gatttaacca tgacctacaa atacaacccc ttctggcagc aacgtattcg
     7741 tgagacggtg cggcacgcac tgaatgttca tccccgcctg acggcattgc gggttgacct
     7801 gcgtttcccg gatgtaccgg cagcaacgga cgcagctgtg atatcccgct tcatcaatgc
     7861 cctgaaagcc cgaatcgacg cttaccagaa acgtaagcat cgggaaggta aacgcgtgca
     7921 tcccacaacc ctgcattacg tctgggcccg ggagtttggg gagtgcaaag gtaaaaaaca
     7981 ctatcacctg atgctgctgg ttaaccggga tacctggtgt cgtgccggtg attaccgtgc
     8041 tccgggatca ctggccggga tgattaaaca ggcgtggtgc agtgccctgg gagtggatgt
     8101 cgggtgccat gccacgctgg tgcattttcc ggcctggccg gcggtgtggc tggaacgcga
     8161 tgatgacact ggctttcagc aggtgctgga acgtgctgac tatctggcga agga
//
LOCUS       DADXDL010000142         7989 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.142, whole genome shotgun sequence.
ACCESSION   DADXDL010000142 DADXDL010000000
VERSION     DADXDL010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7989)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7989)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7989
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.142"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..296
                     /locus_tag="IRB70_004462"
     CDS             <1..296
                     /locus_tag="IRB70_004462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235460.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF2713 family protein"
                     /protein_id="HBC0634300.1"
                     /translation="NLAEMKDLIDKKELDFNVILQEMKNQAGEEKEDIKNITKMQAAG
                     ETLIKFIQSFDPDSTGPIIIGKDMDDKNINDNDLINEDIIKFIYVLLGTELEK"
     gene            658..1695
                     /gene="dusA"
                     /locus_tag="IRB70_004463"
     CDS             658..1695
                     /gene="dusA"
                     /locus_tag="IRB70_004463"
                     /EC_number="1.3.1.-"
                     /EC_number="1.3.1.91"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine(20/20a) synthase DusA"
                     /protein_id="HBC0634301.1"
                     /translation="MHGNSEMQKINQTSAMPEKTDVHWSGRFSVAPMLDWTDRHCRYF
                     LRLLSRNTLLYTEMVTTGAIIHGKGDYLAYSEEEHPVALQLGGSDPAALAQCAKLAEA
                     RGYDEINLNVGCPSDRVQNGMFGACLMGNAQLVADCVKAMRDVVSIPVTVKTRIGIDD
                     QDSYEFLCDFINTVSGKGECEMFIIHARKAWLSGLSPKENREIPPLDYPRVYQLKRDF
                     PHLTMSINGGIKSLEEAKAHLQHMDGVMVGREAYQNPGILAAVDREIFGSSDTDADPV
                     AVVRAMYPYIERELSQGTYLGHITRHMLGLFQGIPGARQWRRYLSENAHKAGADINVL
                     EHALKLVADKR"
     gene            1829..2071
                     /gene="pspG"
                     /locus_tag="IRB70_004464"
     CDS             1829..2071
                     /gene="pspG"
                     /locus_tag="IRB70_004464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313059.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="envelope stress response protein PspG"
                     /protein_id="HBC0634302.1"
                     /translation="MLELLFVIGFFVMLMVTGVSLLGIIAALVVATAIMFLGGMLALM
                     IKLLPWLLLAVAVVWVIKAIKAPKVPKYQRYDRWRY"
     gene            complement(2237..3220)
                     /locus_tag="IRB70_004465"
     CDS             complement(2237..3220)
                     /locus_tag="IRB70_004465"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quinone oxidoreductase"
                     /protein_id="HBC0634303.1"
                     /translation="MATRIEFHKHGGPEVLQTVEFTPADPAENEIQVENKAIGINFID
                     TYIRSGLYPPPSLPSGLGTEAAGIVSKVGSGVKHIKAGDRVVYAQSALGAYSSVHNIN
                     ADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKPDEQFLFHAAAGGVGLIACQW
                     AKALGAKLIGTVGTAQKAQSALKAGAWQVINYREENLVERLKEITAGKKVRVVYDSVG
                     RDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLGILNQKGSLYVTRPSLQGYITTREEL
                     TEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILESRATQGSSLLIP"
     gene            3303..4718
                     /gene="dnaB"
                     /locus_tag="IRB70_004466"
     CDS             3303..4718
                     /gene="dnaB"
                     /locus_tag="IRB70_004466"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBC0634304.1"
                     /translation="MAGNKPFNKQQAEPRERDPQVAGLKVPPHSIEAEQSVLGGLMLD
                     NERWDDVAERVVADDFYTRPHRHIFTEMARLQESGSPIDLITLAESLERQGQLDSVGG
                     FAYLAELSKNTPSAANISAYADIVRERAVVREMISVANEIAEAGFDPQGRTSEDLLDL
                     AESRVFKIAESRANKDEGPKNIADVLDATVARIEQLFQQPHDGVTGVNTGYDDLNKKT
                     AGLQPSDLIIVAARPSMGKTTFAMNLVENAAMLQDKPVLIFSLEMPSEQIMMRSLASL
                     SRVDQTKIRTGQLDDEDWARISGTMGILLEKRNIYIDDSSGLTPTEVRSRARRIAREH
                     GGIGLIMIDYLQLMRVPALSDNRTLEIAEISRSLKALAKELNVPVVALSQLNRSLEQR
                     ADKRPVNSDLRESGSIEQDADLIMFIYRDEVYHENSDLKGIAEIIIGKQRNGPIGTVR
                     LTFNGQWSRFDNYAGPQYDDE"
     gene            4771..5850
                     /gene="alr"
                     /locus_tag="IRB70_004467"
     CDS             4771..5850
                     /gene="alr"
                     /locus_tag="IRB70_004467"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBC0634305.1"
                     /translation="MQAATVVINRRALRHNLQRLRELAPASKMVAVVKANAYGHGLLE
                     TARTLPDADAFGVARLEEALRLRAGGITKPVLLLEGFFDARDLPTISAQHFHTAVHNE
                     EQLAALEEASLDEPVTVWMKLDTGMHRLGVRPEQAEAFYHRLTQCKNVRQPVNIVSHF
                     ARADEPKCGATEKQLAIFNTFCEGKPGQRSIAASGGILLWPQSHFDWVRPGIILYGVS
                     PLEDRSTGADFGCQPVMSLTSSLIAVREHKAGEPVGYGGTWVSERDTRLGVVAMGYGD
                     GYPRAAPSGTPVLVNGREVPIVGRVAMDMICVDLGPQAQDKAGDPVILWGEGLPVERI
                     AEMTKVSAYELITRLTSRVAMKYVD"
     gene            6103..7296
                     /gene="tyrB"
                     /locus_tag="IRB70_004468"
     CDS             6103..7296
                     /gene="tyrB"
                     /locus_tag="IRB70_004468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic amino acid transaminase"
                     /protein_id="HBC0634306.1"
                     /translation="MFQKVDAYAGDPILTLMERFKEDPRSDKVNLSIGLYYNEDGIIP
                     QLKAVADAEARLNAQPHGASLYLPMEGLNSYRHAIAPLLFGADHPVLQQQRVATIQTL
                     GGSGALKVGADFLKRYFPESGVWVSDPTWENHVAIFAGAGFEVSTYPWYDEATNGVRF
                     NDLLATLKTLPARSIVLLHPCCHNPTGADLTNDQWDAVIEILKARELIPFLDIAYQGF
                     GAGMEEDAYAIRAIASAGLPALVSNSFSKIFSLYGERVGGLSVLCEDAEAADRVLGQL
                     KATVRRNYSSPPNFGAQVVAAVLNDEALKASWLAEVEEMRTRILAMRQELVKVLSTEM
                     PERNFDYLLNQRGMFSYTGLSAAQVDRLREEFGVYLIASGRMCVAGLNTANVQRVAKA
                     FAAVM"
     gene            complement(7519..>7989)
                     /locus_tag="IRB70_004469"
     CDS             complement(7519..>7989)
                     /locus_tag="IRB70_004469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001027387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634307.1"
                     /translation="TSLPVELDALNNKDISYSKDFSYAKDFFLYIETQLKIAKDFCRP
                     GEEVSSSIASTVFHAFIDLVNKIRGKKDCMYICTLCCFAEEVKGDYSHYRAFLFDIGN
                     QYKVKLTQSGKKEFSLTLEFNDTIIESQKVTGNKAKHILEDIEIFYRNKPDTYY"
BASE COUNT         1984 a         1885 c         2034 g         2086 t
ORIGIN      
        1 aaaacctggc ggagatgaaa gacttgatag ataaaaaaga attggatttt aatgtaattc
       61 tgcaggagat gaaaaatcag gccggagaag aaaaagaaga catcaaaaac attacaaaaa
      121 tgcaggctgc aggtgagact ttaattaaat ttattcaatc atttgacccg gactcaacgg
      181 gaccaattat aattggtaaa gatatggatg acaaaaatat aaatgacaac gatctaatta
      241 acgaagatat tattaagttc atttatgtcc tattaggtac tgagttagaa aaataaaatg
      301 tgaattttcc ctatagcatg gaagttttta cataaaagaa cccaatattg attgggttct
      361 tttttctcta tcagtgctat tagcagggag agatatcacc gtagtttaat gtgtgatttt
      421 tatttatcgt cgaacctgga ttgtttatca ttggccttaa caaagctaac ggctaataag
      481 attatttcca tcacttcgtg agagcttcat gccttgagag gatctcaatt ttcttttgca
      541 atgagacagg cgcttcctgt tgttatggta tagtaccccg ctattgagcc tcctgaacag
      601 tgatgctgaa taacataacc ccatgatata tcgataaaat aatctctaca tttgaaaatg
      661 cacggtaatt ctgaaatgca aaaaatcaac caaaccagcg caatgcctga aaaaactgac
      721 gttcactgga gtggtcggtt tagcgttgca ccaatgctcg actggacgga cagacattgc
      781 cgctatttct tgcgtctgct ttcccgcaat acgttgctgt ataccgaaat ggtgaccaca
      841 ggggcgatta ttcacggtaa aggtgattat ctggcgtaca gtgaagaaga acatccggta
      901 gcattgcaac tgggcggtag cgatccggcg gcgctggcgc agtgtgcaaa gctggcagaa
      961 gcgcgcggat atgatgagat caacctgaat gtcggctgcc cgtctgaccg ggtgcagaac
     1021 ggcatgtttg gggcgtgtct gatgggtaat gcgcagctgg ttgccgactg cgtgaaagcg
     1081 atgcgcgatg tggtgtcgat tccggtgacg gtgaaaacgc gtattggcat cgacgaccag
     1141 gacagctatg aatttctctg cgatttcatc aacaccgttt ccggcaaagg cgagtgtgag
     1201 atgttcatca tccatgctcg taaagcctgg ctttcggggt taagcccgaa agaaaaccgt
     1261 gaaatcccgc cgctcgatta tccgcgtgtg tatcaactga agcgtgactt tccgcatctg
     1321 acaatgtcga ttaacggtgg tatcaagtcg ctggaagagg ctaaagcgca tttgcaacat
     1381 atggatggcg tgatggtcgg gcgcgaagcg tatcaaaatc cgggtattct ggcggcggta
     1441 gaccgagaga tctttggttc ctcggatacc gatgccgatc cggtggcggt agtgcgcgcc
     1501 atgtatccgt acattgagcg tgaactcagc caggggacgt atcttggcca tattacccgg
     1561 catatgttgg gcttgttcca gggtattcct ggcgcgcggc agtggcggcg ttatttaagt
     1621 gaaaatgccc ataaagcggg tgcagacatt aatgtgctgg aacacgcgct caaactggtg
     1681 gcggataagc gttaactttt caccaaaaag tagtcaaatt caccacgccc tgcgcaccgt
     1741 cgcggggcgt tttgctgtta aatcaataga ttatttttgg catgattctt gtaatgcctg
     1801 caagagattt catatttggg agagcatcat gctggaacta ctttttgtga ttggcttttt
     1861 tgtcatgctg atggtcaccg gcgtttcgtt gctgggcatt atcgccgcgc tggttgtggc
     1921 gacggccatt atgttcctcg gcggtatgct ggcattgatg attaagttgc tgccgtggtt
     1981 actactggcg gttgcggtgg tgtgggttat taaggcgatt aaagcaccaa aagtgccgaa
     2041 atatcagcgt tatgaccgct ggcgttacta agggattgtg cggatgatca caacctaagg
     2101 ttttatcctt agaacaaaat aggaattgat aatcaaatct gtcactattg cgcctctaac
     2161 agattcatcg tgctgtaccc tacatacagc cgaactataa aaagaaaggg cttcccaggt
     2221 ggaagcccta tttcttttat ggaatcaaca ggctggaacc ttgcgtcgcc cggctttcca
     2281 gaatctcatg cgcacgctgc gcatccttca gcggatattt ctgctgctcg gcgacatcga
     2341 ccttaatcac accgctggca atcaaagaga acagttcatt actggcctcg gttaattcct
     2401 cccgcgtggt gatatagcct tgcagggaag ggcgtgtcac atacaacgag cctttctgat
     2461 tgagaatgcc taagttcaca ccggtaaccg cacctgatga gttgccaaaa ctcaccatta
     2521 agccgcggcg ttgcaggcaa tccagcgacc gttcccaggt gtctctgccc acggaatcgt
     2581 acaccacgcg cactttctta ccagcggtga tctctttcaa tcgctcgacc agattctctt
     2641 cacgatagtt aataacctgc cacgcgccgg cttttagcgc gctctgcgct ttttgcgcgg
     2701 ttcctacggt gccgataagt ttcgcgccca gggcttttgc ccactggcag gcaattaagc
     2761 caacgccgcc agccgctgcg tggaacagga actgctcatc gggtttaatt tcataggttt
     2821 tgcgcagcag ataataaacc gttaagcctt tcaggaagga tgccgccgct tgctcaaaag
     2881 aaattgccgc aggcagaatc gccgctttat ccgcattaat gttatgcacc gagctgtaag
     2941 cgcctaacgc cgactgcgca tagactacac gatcgcctgc cttaatatgc tttacaccac
     3001 tgccgacttt actcacgatg cctgccgctt cggtacctaa tccgctgggg agcgatggcg
     3061 gcgggtaaag gccgctgcgg atatacgtgt cgataaaatt gatgccgatg gctttatttt
     3121 cgacctggat ttcattctcc gccggatcgg caggagtgaa ctctacggtt tgaagtactt
     3181 ccgggccacc gtgcttgtga aattcaattc gtgttgccat gtgtcctcca gaacgtatcg
     3241 tcagggtctg cttcatatgg taaagtttcg acccattctt tatctcggta actccattca
     3301 ctatggcagg aaataaaccc ttcaacaaac agcaggctga accccgcgaa cgcgatccac
     3361 aagttgccgg gctgaaagtg cctccgcact cgatcgaagc ggagcagtcg gtgttgggcg
     3421 gtttaatgct ggataacgaa cgctgggacg atgtagccga gcgtgtggtg gcagacgatt
     3481 tttacacccg cccacaccgt catatcttta ctgaaatggc gcgtttacag gaaagcggta
     3541 gtcctatcga tctgattacc cttgcggaat cgctggaacg ccaggggcaa cttgatagcg
     3601 tcggtggttt cgcttatctg gcggagctgt caaaaaatac gccaagtgcg gcgaacatca
     3661 gtgcttatgc tgacatcgtg cgtgaacgtg ccgttgttcg cgagatgatt tcggttgcga
     3721 atgagattgc cgaagccggt tttgatccgc aggggcgtac cagcgaagat ctgctggacc
     3781 tggctgaatc ccgcgtcttt aaaattgccg aaagtcgtgc aaacaaagac gaagggccga
     3841 agaacatcgc cgatgtgctc gacgccacgg tggcgcgtat tgagcagttg tttcagcagc
     3901 cacacgatgg cgttaccggg gtaaacaccg gttatgacga tctcaacaaa aaaaccgctg
     3961 gcttgcagcc gtcggatttg atcatcgtcg ccgcgcgtcc gtcgatgggt aaaacaacat
     4021 ttgcgatgaa cctcgttgaa aacgcggcga tgttgcagga taaaccagta cttatcttct
     4081 cactggagat gccatcagaa cagattatga tgcgttcttt ggcgtcgctg tcgcgcgttg
     4141 accagactaa aatccgtacc gggcagctcg atgatgaaga ctgggcacgt atttccggca
     4201 ccatgggtat tttgctcgaa aaacgtaata tctatatcga tgattcctcc ggcctgacgc
     4261 caacggaagt gcgttcccgc gcgcgccgta ttgcccgtga acacggcggc atcgggctta
     4321 tcatgatcga ctacctgcaa ctgatgcgcg taccggcgct ttccgataac cgtacgctgg
     4381 aaattgcaga aatctcccgc tcgctgaaag cactggcgaa agaactgaac gtgccggtgg
     4441 tggcgctgtc ccagttgaac cgttctctgg aacaacgtgc cgacaaacgc ccggtcaact
     4501 ccgacctgcg tgaatctggc tctatcgagc aggatgcgga cttgatcatg tttatctatc
     4561 gtgatgaggt gtatcacgaa aacagtgatt taaaaggcat cgcggaaatt attatcggta
     4621 aacaacgtaa cggcccaatc gggacggtac gcctgacctt taacggtcaa tggtcgcgct
     4681 tcgacaacta tgcggggccg cagtacgacg acgaataata attattttat gaattaggta
     4741 attaaagcaa acacttatca aggaacacaa atgcaagcgg caactgttgt gattaaccgc
     4801 cgcgctctgc gacacaacct gcaacgtctt cgtgaactgg cacctgccag taaaatggtt
     4861 gcggtggtga aagcgaacgc ttatggtcac ggtcttcttg agaccgcgcg aacgctcccc
     4921 gatgctgacg cctttggcgt agcccgtctc gaagaagctc tgcgactgcg tgcgggggga
     4981 atcaccaaac ctgtactgtt actcgaaggc ttttttgatg ccagagatct gccgacgatt
     5041 tctgcgcaac attttcatac cgccgtgcat aacgaagaac agctggctgc gctggaagag
     5101 gctagcctgg acgagccggt taccgtctgg atgaaactcg ataccggtat gcaccgtctg
     5161 ggcgtaaggc cggaacaggc tgaggcgttt tatcatcgcc tgacccagtg taaaaacgtt
     5221 cgtcagccgg tgaatatcgt cagccatttt gcgcgcgcgg atgaaccaaa atgcggcgca
     5281 accgagaaac aactcgctat ctttaatacc ttttgcgaag gcaaaccagg tcaacgttcc
     5341 attgccgcat cgggtggcat tctgctgtgg ccacagtcgc attttgactg ggtgcgcccg
     5401 ggcatcattc tttacggcgt ctcgccgctg gaagatcgtt ccaccggtgc cgattttggc
     5461 tgtcagccag tgatgtcact aacctccagc ctgattgccg tgcgtgagca caaagccgga
     5521 gagcctgtcg gttatggtgg aacctgggta agcgaacgtg atacccgcct gggcgtagtc
     5581 gcgatgggtt atggcgatgg ttatccgcgc gccgcgccgt ccggtacgcc agtgctggtg
     5641 aacggtcgcg aagtgccgat tgtcgggcga gtcgcgatgg atatgatctg cgtcgactta
     5701 ggtccacagg cgcaggataa agccggggac ccggtcattt tatggggcga aggtttgccc
     5761 gtagaacgta tcgctgaaat gacgaaagta agcgcttacg aacttatcac gcgcctgact
     5821 tcaagggtcg cgatgaaata cgtggattaa tcgttctgta atatttgatt gtctgtgccg
     5881 gatgcggcgt gaatgcctta tccggccaat aaaatcctac caattcaata agttgatttt
     5941 ctttcatgct cttatgaagg tcgtgcctct ggcggatgta cgtttgtcat gagtctcact
     6001 ctgttgctaa ttgccgttcg cccctgaaca tccactcgat cttcgccttc ttccggttta
     6061 ttgtgtttta accacctgcc cgtaaacctg gagaaccatt gcgtgtttca aaaagttgac
     6121 gcctacgctg gcgacccgat tcttacgctt atggagcgtt ttaaagaaga ccctcgcagc
     6181 gacaaagtga atttaagtat cggtctgtac tacaacgaag acggaattat tccacaactg
     6241 aaagccgtgg cggatgcgga agcgcgcctg aatgcgcagc ctcatggcgc ttcgctttat
     6301 ttaccgatgg aagggcttaa cagctatcgc catgccattg cgccgctgct gtttggtgcc
     6361 gaccatccgg tactgcaaca acagcgcgta gcaaccattc aaacccttgg cggctccggg
     6421 gcattgaaag tgggcgcgga tttcctgaaa cgctacttcc cggaatcagg cgtctgggtc
     6481 agcgatccta catgggaaaa ccacgtagca atattcgccg gggctggatt cgaagtaagt
     6541 acttacccct ggtatgacga agcgactaac ggcgtgcgct ttaatgacct gttggcgacg
     6601 ctgaaaacat tacctgcccg cagtattgtg ttgctgcatc catgttgcca caacccaacg
     6661 ggtgctgatc tcactaatga ccaatgggat gcggtgattg aaattctcaa agcccgcgag
     6721 cttatcccat ttcttgatat tgcctatcaa ggatttggtg ctggtatgga agaggatgcc
     6781 tacgccattc gcgccattgc cagcgctgga ttacccgctc tggtgagcaa ttcattctcg
     6841 aaaattttct ccctttacgg cgagcgcgtc ggcggacttt ctgttctgtg tgaagatgcc
     6901 gaagccgcag accgcgtact ggggcaattg aaagcaacag ttcgccgcaa ctactccagc
     6961 ccgccgaatt ttggtgcgca ggtggtggct gcagtgctga atgacgaggc attgaaagcc
     7021 agctggctgg cggaagtaga agagatgcgt actcgcattc tggcaatgcg tcaggaactg
     7081 gtgaaggtat taagcacaga gatgccagaa cgcaatttcg attatctgct taatcagcgc
     7141 ggcatgttca gttataccgg tttaagtgcc gctcaggttg accgactacg tgaggagttt
     7201 ggtgtttatc tcatcgccag cggtcgcatg tgtgtcgccg ggttaaatac ggcaaatgta
     7261 caacgtgtag caaaggcgtt tgctgcggta atgtaatgca ggaaagcagg ctggagttac
     7321 ccagcctgca gtgaaattaa actgtcgtcg ttttcactct ttctttgtag atgatttttt
     7381 tgatgccatc gttttacgtg agggataata aaaggttgtc agttctttta ttgttaagtt
     7441 tatcccaatt atctggaatt tctttccctg ttttttcgtg tggagtaata atttctgcac
     7501 atctaaccat tattaaattt aataataagt atcgggtttg ttacgataga atatttctat
     7561 atcctcaaga atatgctttg ccttattgcc tgtgactttc tgagattcaa ttatagtatc
     7621 gttaaattct aatgttaaag agaactcttt ttttccgctt tgtgtaagtt taaccttata
     7681 ttgattacca atatcaaata aaaaggccct gtaatgagaa taatcacctt taacctcctc
     7741 ggcaaaacag caaagtgtgc aaatatacat acaatctttc ttgcctctga ttttgttaac
     7801 taaatcaata aatgcatgaa aaactgtact tgcaatagaa cttgatactt cttctccagg
     7861 tctacaaaaa tcttttgcaa tttttaactg tgtttctata tataaaaaga aatctttggc
     7921 ataagaaaaa tctttggaat aagagatatc tttattattt agtgcatcta gctcaacagg
     7981 taaagatgt
//
LOCUS       DADXDL010000143         7919 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.143, whole genome shotgun sequence.
ACCESSION   DADXDL010000143 DADXDL010000000
VERSION     DADXDL010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7919)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7919)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7919
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.143"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(745..1125)
                     /locus_tag="IRB70_004470"
                     /pseudo
     CDS             complement(745..1125)
                     /locus_tag="IRB70_004470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416847.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1492..2832)
                     /gene="fadL"
                     /locus_tag="IRB70_004471"
     CDS             complement(1492..2832)
                     /gene="fadL"
                     /locus_tag="IRB70_004471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708225.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="long-chain fatty acid transporter FadL"
                     /protein_id="HBC0634308.1"
                     /translation="MSQKTLFTKSALAVAVALISTQAWSAGFQLNEFSSSGLGRAYSG
                     EGAIADDAGNVSRNPALITMFDRPTFSAGAVYIDPDVNISGTSPSGRSLKADNIAPTA
                     WVPNMHFVAPINDQFGWGASITSNYGLATEFNDTYAGGSVGGTTDLETMNLNLSGAYR
                     LNNAWSFGLGFNAVYARAKIERFAGDLGQLVAGQIMQSPARQTPQGQALAATANGIDS
                     NTKIAHLNGNQWGFGWNAGILYELDKNNRYALTYRSEVKIDFKGNYSSDLNPAFNNYG
                     LPIPTATGGATQSGYLTLNLPEMWEVSGYNRVDPQWAIHYSLAYTSWSQFQQLKATST
                     SGDTLFQKHEGFKDAYRIALGTTYYYDDNWTFRTGIAFDDSPVPAQNRSISIPDQDRF
                     WLSAGTTYAFNKDASVDVGVSYMHGQSVKINEGPYQFESEGKAWLFGTNFNYAF"
     gene            3204..3488
                     /locus_tag="IRB70_004472"
     CDS             3204..3488
                     /locus_tag="IRB70_004472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005129756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcZ/YiiS family protein"
                     /protein_id="HBC0634309.1"
                     /translation="MSKCSADETPVCCCMDVGTIMDNSDCTASYSRVFANRAEAEQTL
                     AALTEKARSVESEPCKITPTFTEESDGVRLDIDFTFACEAEMLIFQLGLR"
     gene            3669..4979
                     /gene="fadI"
                     /locus_tag="IRB70_004473"
     CDS             3669..4979
                     /gene="fadI"
                     /locus_tag="IRB70_004473"
                     /EC_number="2.3.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA C-acyltransferase FadI"
                     /protein_id="HBC0634310.1"
                     /translation="MGQVLPLVTRQGDRIAIVSGLRTPFARQATAFHGIPAVDLGKMV
                     VGELLARTEIPAEVIEQLVFGQVVQMPEAPNIAREIVLGTGMNVHTDAYSVSRACATS
                     FQAIANVAESLMAGTIRAGIAGGADSSSVLPIGVSKKLARVLVDVNKARTMSQRLKLF
                     SRLRLRDLMPVPPAVAEYSTGLRMGDTAEQMAKTYGITREQQDALAHRSHQRAAQAWS
                     DGKLKEEVMTAFIPPYKQPLVEDNNIRGNSSLADYAKLRPAFDRKHGTVTAANSTPLT
                     DGAAAVILMTESRAKELGLVPLGYLRSYAFTAIDVWQDMLLGPAWSTPLALERAGLTM
                     SDLTLIDMHEAFAAQTLANIQLLGSERFARDVLGRAHATGEVDESKFNVLGGSIAYGH
                     PFAATGARMITQTLHELRRRGGGFGLVTACAAGGLGAAMVVEAE"
     gene            4979..7123
                     /gene="fadJ"
                     /locus_tag="IRB70_004474"
     CDS             4979..7123
                     /gene="fadJ"
                     /locus_tag="IRB70_004474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fatty acid oxidation complex subunit alpha FadJ"
                     /protein_id="HBC0634311.1"
                     /translation="MEMASAFTLNVRLDNIAIITIDVPGEKMNTLKAEFASQVRAIIK
                     QLRENKELRGVVFISAKPDNFIAGADINMIGNCKTAQEAEVLARQGQQLMAEIHALPV
                     PVIAAIHGACLGGGLELALACHGRVCTDDAKTVLGLPEVQLGLLPGSGGTQRLPRLIG
                     VSTALEMILTGKQLRAKQALKLGLVDDVVPHSILLEAAVELAKQDRPSSRPLPVRERI
                     LAGPLGRALLFKMVGKKTEHKTQSNYPATERILEVVETGLAQGTSSGYDAEARAFGEL
                     AMTPQSQALRNIFFASTEVKKDPGSDAPPAPLNSVGILGGGLMGGGIAYVTACKAGLP
                     VRIKDINPQGINHALKYSWDQLEGKVRRRHLKASERDKQLALISGTTDYCGFAHRDLI
                     IEAVFENLELKQQMVAEVEQNCATHTIFASNTSSLPIGDIAAHAARPEQVIGLHFFSP
                     VEKMPLVEIIPHASTSAQTIATTVKLAKKQGKTPIVVRDKAGFYVNRILAPYINEAIR
                     MLTEGERIEHIDAALVKFGFPVGPIQLLDEVGIDTGTKIMPVLEAAYGERFSAPANVV
                     SSILNDDRKGRKNGRGFYLYGQKGRKSKKQVDPAIYPLIGAQGQGRLSAPQVAERCVM
                     LMLNEAVRCLDEQVTRSVRDGDIGAVFGIGFPPFLGGPFRYIDSLGAGEVVAIMQRLA
                     TQYGSRFTPCERLVEMSKRGESFWKTTATDLQ"
     gene            7326..7811
                     /gene="sixA"
                     /locus_tag="IRB70_004475"
     CDS             7326..7811
                     /gene="sixA"
                     /locus_tag="IRB70_004475"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohistidine phosphatase SixA"
                     /protein_id="HBC0634312.1"
                     /translation="MQVFIMRHGDAALDAASDSVRPLTTNGCDESRLMANWLKGQNVE
                     IERVLVSPFLRAEQTLEEVGDCLNLPSSAEVLPELTPCGDVGLVSAYLQALTNEGVAS
                     VLVISHLPLVGYLVAELCPGETPPMFTTSAIASVTLDESGKGQFNWQMSPCNLKMAKA
                     I"
BASE COUNT         1967 a         1820 c         2009 g         2123 t
ORIGIN      
        1 attttgagaa aggtcaactt cgttatcgac taaagtagaa attatttctt ttacattatc
       61 gcgtctaaat tttgcatcgt ccacttgaaa attatatctt attgctcgac ctaaacgttt
      121 aaaaacttcg tttggctctc tcagtctttc cccgttgagc tcgtttacaa cctgatgatc
      181 ggaacctgtt gcaaatgatt ctgccatcat agctttactg ctttcaaacc acgctgaagc
      241 attcctggct ttttcactac aatattgggt gagactatca ccattaatac gaattcctct
      301 ttgaatgtgg tagtcgtcct gatcatagta accgagagat aagtaatcat ttccgttttt
      361 atttttaatt acaatagcga gagaatcgcc ttttttatct ttaccgtacc aggtaaataa
      421 gtccgttggt tcgcttttcc cattctcatc aaattccgtt atcgtatgtc tgagtttttg
      481 tgatatctta ttgaagataa aatcaggatc tccatcatat atttctttta atgcgctgaa
      541 gatcatttcc ttgttattga tatcatgagt attctctact acattttcat ggatgatagt
      601 ttggccgact tttttgtttt catcgttcgt aggtgatttt attggttctt gattatagat
      661 accactagta atatcggctg tatcattgga gtcaatagca ccctcattac cactaacaac
      721 gatactacca tcagtaaagt cagcattatt tatatcatca tgagtcttct caactatgtt
      781 gtcattaatg atagcacgga cgagttcttt gtctttatag ctcgcaagta attttattgt
      841 ttcttggtta tcgataccaa tagtaatata gtctgtatca ttggagccaa tatcaatata
      901 agtaactgag gaattattaa tattaaatct atcaggattg tcgtttcctc gtatggcgtt
      961 ttttataagc gcaagtagat gtttaacaca ggtgcttatt ccttgcttac cattaaaaag
     1021 gtttttgagc tcttgtacta atatattaac ttcatcattg ttattttcat tgatggattc
     1081 tgtgtaagct gcgctggtat tgttgattga aatagatggt agcatgattt tattccatgt
     1141 tgattgattt gttacaaata tatattacct gataaaatag actatcaaaa aacgctcatt
     1201 tatttagacc ctatctttaa tttgagtgta tgagcgcaca atagccaggg tggtttgagt
     1261 atcctggaaa ttcagaaaag taaactcttt gagaaagacg agcagaacgc ctgaaaataa
     1321 gcctttccct tcaggtttgt ctgtggatac cacttaatga tttgaaaggg caagctacca
     1381 tcaggctgtt tgcaaaactc aggaggcaag caatgaggaa acaactttcg ttgaagtgtg
     1441 ggagttaaag tcacctgcat agcaggtgac tttatccagg cgaacgcgtt atcagaacgc
     1501 gtagttaaag ttagtaccga acagccaggc tttaccttca gactcgaact ggtatgggcc
     1561 ttcgttaatt ttcacgctct gaccgtgcat ataagaaaca ccaacatcga ctgaagcatc
     1621 tttattaaat gcgtaagtcg tacctgcact cagccagaaa cggtcctggt ccggaatgga
     1681 gatagaacga ttctgtgccg gaactgggct gtcatcaaag gcgataccgg tacggaaggt
     1741 ccagttatca tcgtagtaat aagtggttcc caacgcgatg cggtaagcat ctttaaagcc
     1801 ttcatgtttc tggaacagcg tgtcgccact cgttgaggtc gctttcagct gctggaactg
     1861 actccagctg gtgtaagcca ggctatagtg aatcgcccac tgcggatcaa cacggttata
     1921 acccgacact tcccacattt caggcaggtt cagcgtcaga taacccgatt gcgttgcgcc
     1981 acctgtcgcg gtaggaattg gcaaaccgta gttattaaaa gccgggttaa gatcgctgct
     2041 gtagttaccc ttgaagtcaa ttttcacttc agagcggtag gtcaatgcgt agcggttgtt
     2101 tttatccagt tcgtacagga tcccggcgtt ccagccaaag ccccactggt taccgttcag
     2161 gtgagcgatt ttggtattac tgtcgatgcc gttggcggta gctgctaatg cttgcccctg
     2221 aggagtctgc ctggcaggag attgcataat ctgaccagca accagctgcc ccagatcgcc
     2281 tgcgaaacgt tcaattttcg cgcgagcgta gacggcgttg aaaccaagac caaagctcca
     2341 tgcattattt aagcgatacg caccgcttaa gttcaggttc atggtttcaa ggtcggttgt
     2401 acccccgaca gagccgcctg cataagtatc gttaaactct gttgccaggc catagttaga
     2461 ggtaatagaa gcgccccaac caaattggtc gttaatcggt gcaacaaagt gcatgttcgg
     2521 aacccatgcc gtaggcgcga tgttatcggc tttcaggcta cggccagatg gagacgttcc
     2581 gctgatattt acatccggat caatataaac cgcacccgca gaaaatgtcg ggcggtcaaa
     2641 catggtaatc aatgcggggt tacggctaac gttacctgca tcatcggcaa ttgcgccttc
     2701 ccctgaataa gcccggccca ggccagagga agaaaattcg tttaactgaa agcctgccga
     2761 ccaggcctgg gtggagataa gtgccactgc gactgcgaga gcagactttg taaacagggt
     2821 tttctggctc atgaccataa cctcaatgat ttatttttat acaaactatg ttacgtgctg
     2881 taacaggagc gcgaagtgta gggtctgagg tacatcttag aaatcagacc agtggcgaga
     2941 gtataggtcg gaccagctgg aatgttgcaa gtatgtttct atcttttttc aaatatgatc
     3001 taagaaacgc gatccagctg gcaaaatttg gaggtggcgc actcatggat tcgggtgaat
     3061 tttgttttag atcattttta agtgtgattt cggtcactta tccgattttg cagaattaac
     3121 aactggagca gcactttccg gaagcgtaaa atatccacaa cgtttatctg gcaccttggg
     3181 tgcacataca gaggaaatca acgatgagta aatgtagtgc tgatgaaacc ccggtttgct
     3241 gctgtatgga tgttggcacc attatggaca actccgactg caccgcgtct tacagccgcg
     3301 tgtttgcaaa ccgcgcagaa gcagaacaaa cgctggcggc gctgactgaa aaagcccgta
     3361 gcgtggaatc cgaaccgtgc aaaatcaccc cgactttcac tgaagagtct gacggtgtac
     3421 gcctggatat cgatttcact tttgcctgcg aagctgaaat gttgatcttc cagctgggtc
     3481 tgcgttaatt cctctcgggt acgtacgccc ctgtcagttc ctggcggggg cgttttattt
     3541 tctcttctac ttttctctct gtgtcatagc tcccactttc ccttttctcc acttggctaa
     3601 atgtaaaaaa atggttaaga ctatgatcag gtcagaccac tttatttatt attttacagg
     3661 ggagtgttat gggtcaggtt ttaccgctgg ttacccgcca gggcgatcgt atcgccattg
     3721 ttagcggttt acgtacgcct tttgcccgcc aggcgacggc ttttcatggc attcccgcgg
     3781 ttgatttagg gaagatggtg gtaggcgaat tgctggcacg caccgagatc cccgccgaag
     3841 tgattgaaca actggttttt ggtcaggtcg tacaaatgcc tgaagccccc aacattgcgc
     3901 gtgaaattgt tctcggtacc ggaatgaatg tgcataccga tgcttacagc gtcagccgcg
     3961 cttgcgctac cagtttccag gcgattgcaa acgtcgcaga aagtctgatg gcgggaacta
     4021 ttcgcgcggg gattgccggt ggggccgatt cttcttccgt attgcccatt ggcgtcagta
     4081 aaaaactggc gcgcgtgctg gttgatgtca acaaagctcg aaccatgagc cagcgcctga
     4141 aactcttctc tcgcctgcgt ttacgcgact taatgcccgt accgcctgcg gtagcagagt
     4201 attctaccgg cttgcggatg ggggacaccg ccgaacaaat ggcgaaaacc tacggtatta
     4261 ctcgcgaaca gcaagatgca ctggcgcacc gttcgcatca gcgtgccgct caggcgtggt
     4321 cagacggtaa actcaaagaa gaggtgatga ctgcctttat ccctccttat aaacaaccgc
     4381 ttgtcgaaga caacaatatt cgcggtaatt cctctcttgc tgattacgca aagctgcgtc
     4441 cggcgtttga tcgtaaacac gggacggtaa cggcggcgaa cagtacacca ctgaccgatg
     4501 gcgcagcggc ggtgatcctg atgactgaat cccgggcgaa agaattaggg ctggtaccgc
     4561 tggggtatct gcgcagctac gcatttactg cgatagatgt ctggcaggac atgttgctcg
     4621 gcccggcctg gtcaacgccg ctggcgctgg aacgtgccgg tttgacaatg agcgatctga
     4681 cattgatcga tatgcacgaa gcctttgcag ctcagacact ggcgaatatt cagttgctgg
     4741 gtagcgaacg ttttgctcgt gatgtactgg ggcgtgcaca tgccactggc gaagtggacg
     4801 agagcaaatt taacgtgctt ggcggttcga ttgcttacgg gcatcccttc gcagcgaccg
     4861 gcgcgcggat gattacccag acattgcatg aacttcgccg tcgcggcggt ggatttggtt
     4921 tagtgaccgc ctgtgctgcg ggtggacttg gcgcagcaat ggttgtggag gcggaataat
     4981 ggaaatggca tcagcgttta ctcttaatgt tcgtctggac aacattgcta tcatcaccat
     5041 cgacgtaccg ggtgagaaaa tgaataccct gaaggcggaa tttgcctcgc aggtgcgcgc
     5101 cattattaag caactccgtg aaaacaaaga gttgcgcggc gtggtgttta tctccgcgaa
     5161 accagacaac ttcattgctg gcgcagacat caacatgatc ggcaattgca aaacggcgca
     5221 agaagcggaa gtactggcgc ggcaggggca acagttaatg gcggagattc atgctttgcc
     5281 cgttccggtt atcgcggcta ttcatggcgc ttgcctgggc ggcgggctgg agttggcgct
     5341 ggcgtgccac ggtcgcgtgt gtactgatga tgctaaaacg gtgctcggtt tgcctgaagt
     5401 acaacttgga ttgttacccg gttcaggcgg cacccagcgt ttaccgcgcc tgattggcgt
     5461 cagcaccgcg ctggagatga tcctcacggg caagcaacta cgggcaaagc aggctttaaa
     5521 actggggctg gtggatgacg tcgttccgca ctccatattg ctggaagccg ctgttgagct
     5581 ggcaaagcag gatcgtccat cttcacgccc tctacctgta cgcgagcgta ttctggcggg
     5641 gccgttaggt cgtgcgctgc tgttcaaaat ggtcggcaag aaaacagaac acaaaactca
     5701 aagtaactat ccggcgacag aacgcatcct ggaggttgtc gaaacgggat tagcgcaggg
     5761 caccagtagc ggctatgacg ctgaagcacg ggcgtttgga gaactggcga tgacgccgca
     5821 atcgcaggcg ctgcgcaata tcttttttgc cagtacggaa gtgaaaaaag atcccggcag
     5881 tgatgcgccg cctgcgccat taaacagcgt gggaatttta ggtggtggct tgatgggcgg
     5941 cggtattgct tacgtcactg cttgtaaagc ggggcttccg gtcagaatta aagatatcaa
     6001 cccgcagggc ataaatcatg cattgaagta cagctgggat cagttggagg gcaaagttcg
     6061 ccgtcgtcat ctcaaagcca gcgaacgtga caaacagctg gctttaatct ccggaacgac
     6121 ggactattgc ggctttgccc atcgcgatct gattattgaa gcggtgtttg aaaatctcga
     6181 attaaaacaa cagatggtgg cggaagtgga gcaaaattgc gctactcata ccatctttgc
     6241 ttcgaacacg tcatctttac cgattggcga tatcgccgct cacgccgcgc gacctgagca
     6301 agttattggc ctgcatttct tcagtccggt ggaaaaaatg ccgctggtgg agattattcc
     6361 tcatgcgagt acatcggcgc aaaccatcgc caccacggta aaactggcga aaaaacaggg
     6421 caaaacgcca attgtcgtgc gtgacaaagc cgggttttac gtcaatcgca ttttagcgcc
     6481 ttacatcaat gaagctatcc gcatgttgac cgaaggcgag cgtattgagc atatcgatgc
     6541 cgcgctggtg aaatttggtt ttccggtagg cccaatccaa cttttggatg aggtaggaat
     6601 cgacaccggg actaaaatta tgcctgtact ggaagctgct tatggagaac gttttagcgc
     6661 gcctgcaaat gttgtttctt caattttgaa cgacgatcgc aaaggcagaa aaaatggccg
     6721 gggtttctat ctttatggtc agaaagggcg taaaagcaaa aaacaggtcg atcccgccat
     6781 ttacccgctc attggcgcac aagggcaggg gcgactctcc gcaccgcagg ttgctgaacg
     6841 gtgtgtgatg ttgatgctga atgaagcagt acgttgtctg gacgagcagg ttacccgtag
     6901 cgtacgtgac ggggatattg gcgcggtatt tggcattggt tttccgccgt ttctcggtgg
     6961 accgttccgc tatatcgatt ctctcggcgc aggcgaagtg gttgcaataa tgcaacgact
     7021 ggccacgcag tatggttccc gttttacccc ttgcgagcgt ttagtcgaga tgagcaagcg
     7081 tggggaaagt ttttggaaaa caactgcaac tgacctgcaa taagaaggtc aaagctatat
     7141 gaatccgcgc tgaatggcgg agtgttgctc aaaatgtaaa cgcatattga ctatacttac
     7201 gccattgagg taaaaaacag cgtttcattc ggtgaatgga taaggcacaa tgccggccac
     7261 cgttttcttt ctctggtttc agatgaaaga aaacgggcga atctggttaa caaaagcggt
     7321 gcaatatgca agtttttatc atgcgtcacg gcgacgcagc cctcgatgcc gccagtgatt
     7381 cggttcgtcc tctgactact aacggttgtg acgaatctcg cctgatggcg aactggctga
     7441 aaggtcaaaa cgtggaaatc gaacgcgttc tggtgagccc gttcctgcga gccgagcaaa
     7501 cacttgaaga agtaggggat tgtctgaacc tgccttccag tgcagaagtt ctgccggagt
     7561 taacaccctg cggcgatgtt ggtctggtca gtgcctattt gcaggcgttg accaatgaag
     7621 gtgttgcttc ggtactggtg atctcccact tacccttagt cgggtatctg gttgccgagt
     7681 tatgtccggg cgaaacgccg cctatgttta ccacgtcagc gattgccagc gtaacgcttg
     7741 atgaaagcgg aaaaggccaa ttcaactggc aaatgagccc ttgtaatttg aagatggcaa
     7801 aagcaattta agcaatcaat gcccggttac gtgcgcgtac accgggcagt ttctccgtca
     7861 tacaatcatt ctttttcttg tctaaatgtt gttaatattt aacaactctc gatagttat
//
LOCUS       DADXDL010000144         7849 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.144, whole genome shotgun sequence.
ACCESSION   DADXDL010000144 DADXDL010000000
VERSION     DADXDL010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7849
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.144"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            124..1467
                     /locus_tag="IRB70_004476"
     CDS             124..1467
                     /locus_tag="IRB70_004476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBC0634313.1"
                     /translation="MANSITADEIREQFSQAMSAMYQQEVPQYGTLLELVADVNLAVL
                     ENNPQLHEKMVNADELARLNVERHGAIRVGTAQELATLRRMFAIMGMYPVSYYDLSQA
                     GVPVHSTAFRPIDDASLARNPFRIFTSLLRLELIENEFLRQKAAEILRQRDIFTPRCR
                     QLLEEYEQRGGFNETQAQEFVQEALETFRWHQSATVDEETYRALHNEHRLIADVVCFP
                     GCHINHLTPRTLDIDRVQSMMPECGIEPKILIEGPPRREVPILLRQTSFKALEETVLF
                     AGQKQGTHTARFGEIEQRGVALTPKGRQLYDDLLRNAGTGQDNLTHQMHLQETFRTFP
                     DSEFLMRQQGLAWFRYRLTPSGEAHRQAIHSGDDPQPLIERGWVVAQPITYEDFLPVS
                     AAGIFQSNLGNETQARSHGNASREAFEQALGCPVLDEFQLYQEAEERSKRRCGLL"
     gene            1692..3347
                     /gene="opgD"
                     /locus_tag="IRB70_004477"
                     /gene_synonym="mdoD"
     CDS             1692..3347
                     /gene="opgD"
                     /locus_tag="IRB70_004477"
                     /gene_synonym="mdoD"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucan biosynthesis protein OpgD"
                     /protein_id="HBC0634314.1"
                     /translation="MDRRRFIKGSMAMAAVCGTSGIASLFSQAAFAADSDIADGQTQR
                     FDFSILQSMAHDLAQTAWRGAPRPLPDTLATMTPQAYNSIQYDAEKSLWHNVENRQLD
                     AQFFHMGMGFRRRVRMFSVDPATHLAREIHFRPELFKYNDAGVDTKQLEGQSDLGFAG
                     FRVFKAPELARRDVVSFLGASYFRAVDDTYQYGLSARGLAIDTYTDSKEEFPDFTAFW
                     FDTVKPGATTFTVYALLDSASITGAYKFTIHCEKSQVIMDVENHLYARKDIKQLGIAP
                     MTSMFSCGTNERRMCDTIHPQIHDSDRLSMWRGNGEWICRPLNNPQKLQFNAYTDNNP
                     KGFGLLQLDRDFSHYQDIMGWYNKRPSLWVEPRNKWGKGTIGLMEIPTTGETLDNIVC
                     FWQPEKAVKAGDEFAFQYRLYWSAQPPVHCPLARVMATRTGMGGFPEGWAPGEHYPEK
                     WARRFAVDLVGGDLKAAAPKGIEPVITLSSGEAKQIEILYIEPIDGYRIQFDWYPTSD
                     STDPVDMRMYLRCQGDAISETWLYQYFPPAPDKRQYVDDRVMS"
     gene            3487..3711
                     /locus_tag="IRB70_004478"
     CDS             3487..3711
                     /locus_tag="IRB70_004478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415943.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcH family protein"
                     /protein_id="HBC0634315.1"
                     /translation="MFPEYRDLISRLKNENPRFMSLFDKHNKLDHEIARKEGSDGRGY
                     NAEVVRMKKQKLQLKDEMLKILQQESVKEV"
     gene            3774..4313
                     /gene="rimL"
                     /locus_tag="IRB70_004479"
     CDS             3774..4313
                     /gene="rimL"
                     /locus_tag="IRB70_004479"
                     /EC_number="2.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12-serine
                     acetyltransferase"
                     /protein_id="HBC0634316.1"
                     /translation="MTETIKVSESLELHAVAESHVTPLYLLICKNRTWLQQSLNWPQF
                     VQSEEDTRKTVQGNVMLHQRGYAKMFMIFKEDELIGVISFNRIEPLNKTAEIGYWLDE
                     SHQGQGIISQALQALIHHYAQSGELRRFVIKCRVDNPQSNQVALRNGFILEGCLKQAE
                     FLNDAYDDVNLYARIIDSQ"
     gene            complement(4305..5285)
                     /locus_tag="IRB70_004480"
     CDS             complement(4305..5285)
                     /locus_tag="IRB70_004480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LbetaH domain-containing protein"
                     /protein_id="HBC0634317.1"
                     /translation="MRKYRLSEEQRAFSYQEDGTKKNVLLRQIIAISDFNDVIAGSAG
                     GWIDRETVLAQEGNCWIYDQNAIAFGGTVISGNTRITGTSVLWGEVYATDNVWIDNSE
                     ISQGAHISDSVTIRGSLVCGQCRIFGHALIDQHSMIVAAQGLTPDHQLLLQIYDRARV
                     SASRIVHQAQIYGDAVVRYAFIEHRAEVFDFASIEGNEENNVWLCDCAKVCGHAQVKA
                     GIEEDAIPTIHYSSQVAEYAIVEGNCVLKHHVLIGGNAVVRGGPILLDEHVVIQGESR
                     ITGAVIIENHVELTDHAVVEAFDGDTVHVRGPKVINGEERITRTPLAGLL"
     gene            5409..6401
                     /gene="tehA"
                     /locus_tag="IRB70_004481"
     CDS             5409..6401
                     /gene="tehA"
                     /locus_tag="IRB70_004481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dicarboxylate transporter/tellurite-resistance
                     protein TehA"
                     /protein_id="HBC0634318.1"
                     /translation="MQSDKVLNLPAGYFSIVLGTIGMGFAWRYASQVWQVSHWLGDGL
                     VILAMIIWGLLTGAFITRLIRFPHSVLAEVRHPVLSSFVSLFPATTMLVAIGFVPWFR
                     PLAVCLFSFGVVVQLAYAAWQTAGLWRGSHPEEATTPGLYLPTVANNFISAMACGALG
                     YTDAGLVFLGAGVFSWLSLEPVILQRLRSSGELPTALRTSLGIQLAPALVACSAWLSV
                     NGGEGDTLAKMLFGYGLLQLLFMLRLMPWYLSQPFNASFWSFSFGVSALATTGLHLGI
                     GSDNGFFHTLAVPLFIFTNFIIAILLIRTFALLMQGKLLIRTERAVLMKAEDKE"
     gene            6398..6991
                     /gene="tehB"
                     /locus_tag="IRB70_004482"
     CDS             6398..6991
                     /gene="tehB"
                     /locus_tag="IRB70_004482"
                     /EC_number="2.1.1.265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tellurite resistance methyltransferase TehB"
                     /protein_id="HBC0634319.1"
                     /translation="MIIRDENYFTDKYELTRTHSEVLEAVKVVKPGKTLDLGCGNGRN
                     SLYLAANGYDVDAWDKNAMSIANVERIKSIENLDNLHTRVVDLNNLTFDGQYDFILST
                     VVLMFLEAKTIPGLIANMQRCTKPGGYNLIVAAMDTADYPCTVGFPFAFKEGELRRYY
                     EGWERVKYNEDVGELHRTDANGNRIKLRFATMLARKK"
     gene            7294..>7849
                     /locus_tag="IRB70_004483"
     CDS             7294..>7849
                     /locus_tag="IRB70_004483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3313 domain-containing protein"
                     /protein_id="HBC0634320.1"
                     /translation="MRTTSIAKVAALCGLLALSGCASKITQPDKYSGFLNNYSDLKET
                     NSATGKPVLRWVDPSFDQSKYDSIVWNPITYYPVPKPSTQVGQKVLDKILNYTNTEMK
                     EAIAQRKPLVTTAGPRSLIFRGAITGVDTSKEGLQFYEVVPVALVVAGTQMATGHRTM
                     DTRLYFEGELIDAATNKPVIKVVRQ"
BASE COUNT         1979 a         1844 c         1963 g         2063 t
ORIGIN      
        1 tatgttacag caaaatggat aatattgatg ttttcgcggc gagatcacag tttgtaaatt
       61 cttcccgccg gagtgaatgc ggttacctac actccagatt actgaccact ggaggcagac
      121 actatggcga acagcatcac ggcggatgag attcgggaac agttttcgca ggcaatgtca
      181 gccatgtacc agcaagaagt tccgcagtac ggcacgctgc tggaactggt agctgatgtg
      241 aatctggctg tgctggaaaa caatcctcaa ctgcacgaaa aaatggtaaa tgcagacgag
      301 ctggcgcgac tgaatgttga acgtcatggg gcgattcgtg ttgggactgc acaagagctt
      361 gctactcttc ggcggatgtt tgccattatg gggatgtacc cggtgagcta ttacgatctc
      421 tcgcaggcgg gagtgccggt acattccaca gcatttcggc ccattgatga tgcttctctg
      481 gcgcgtaatc cattccgcat ttttacctca ttactccgcc ttgagcttat cgagaacgaa
      541 tttttgcgcc agaaagcggc ggagattctg cgtcagcgcg atatcttcac cccacgttgt
      601 cgacaactgt tagaggaata tgagcagcgg ggcggtttta acgaaacaca ggcacaggag
      661 tttgtgcagg aagccctgga aacgtttcgt tggcaccagt cagcaacggt agatgaagaa
      721 acctatcgcg ccttgcacaa cgaacatcgg ttgattgctg atgtggtctg ttttcctgga
      781 tgccatatca accacctgac gccacgtacg ctggatattg accgggtgca gtcgatgatg
      841 cctgaatgcg ggattgaacc caaaattctg atcgaagggc cgccgcgccg cgaggtacct
      901 attttactac gccagaccag ctttaaagca ctggaagaga cggtgttgtt tgcagggcag
      961 aaacagggta cgcataccgc gcgctttggt gaaatagagc agcgtggtgt ggcattaacg
     1021 ccgaaagggc gacaactgta tgatgatctt ctgcgtaacg ctggaaccgg gcaggataat
     1081 ctcactcacc aaatgcattt acaggaaacc ttccgcactt ttcctgacag tgagttttta
     1141 atgcgtcagc aagggttggc atggttccgg taccgtctga cgccttcagg tgaggcgcat
     1201 cgtcaggcga ttcattccgg agacgatcca cagcccttaa ttgaacgtgg ttgggtagtg
     1261 gcgcaaccca ttacctatga agatttcttg cctgttagcg cggcggggat cttccagtca
     1321 aatctgggta atgaaacgca ggcacgcagt cacggtaatg ccagtcgcga agcatttgag
     1381 caggcgttgg gctgcccggt tttggatgag ttccagcttt atcaggaagc ggaagaacgc
     1441 agtaaacgtc gctgtggttt gctttaaatt ctgaccatcc gcctttgcaa aaatttgcct
     1501 gattttacaa acgaatcagg ctcatcccat cgacataaaa aaaatgccaa tttatgcata
     1561 ttctctgagt tcaacaattg gattattaat aaatattgtc tagagtgagc ggtcataaat
     1621 aagcactttc ttgccgctga aaacgaccag cgcgggacca ttcacaacac cagaaggact
     1681 cactttcagg tatggatcgt agacgattta ttaaaggttc aatggctatg gccgccgtgt
     1741 gcggtaccag cggcattgct tctctttttt ctcaggcggc attcgcggca gattctgata
     1801 ttgccgacgg gcaaacccag cgttttgact tctccattct acagtcaatg gcgcacgact
     1861 tagcgcaaac cgcgtggcgt ggtgcgccgc gtccgttacc tgacactctg gcgacaatga
     1921 cgccgcaggc ttataacagt attcaatacg acgccgaaaa atcgctctgg cataacgttg
     1981 agaaccgtca actggacgct cagttcttcc atatgggaat gggattccgt cgccgcgttc
     2041 gtatgttttc tgttgatccc gcaacacatc tggcgcgtga aattcacttt cgcccggagt
     2101 tgttcaaata caacgatgcg ggtgttgata ccaaacaatt agaagggcaa agcgatctcg
     2161 gttttgccgg ttttcgcgtg tttaaagccc ccgaactggc gcgccgtgat gtcgtatcat
     2221 tcctcggcgc gagttatttc cgcgccgttg atgatacata tcaatacggt ttgtcggccc
     2281 gcggcctggc gatcgacact tacaccgaca gtaaagaaga gttccccgac tttaccgcct
     2341 tctggtttga tacggtaaaa ccgggggcaa ccacctttac cgtttatgcg ttgctcgata
     2401 gcgccagcat tactggtgcc tataagttca ctatccattg cgagaaaagt caggtgatta
     2461 tggatgtgga aaatcacctg tatgcgcgca aagacattaa acagctgggc attgcgccga
     2521 tgaccagtat gttcagctgc ggtactaatg aacgtcggat gtgcgacacc attcatccgc
     2581 aaatccatga ctctgatcgt ttgtccatgt ggcggggcaa cggcgagtgg atttgtcgtc
     2641 cgctgaacaa tccgcaaaaa ttgcagttca atgcttacac cgacaacaac ccgaaagggt
     2701 ttggtttatt gcaactggat cgtgatttct cccattatca ggacattatg ggctggtata
     2761 acaaacgccc aagtctgtgg gtggaaccgc gtaacaagtg gggtaagggc accatcggcc
     2821 tgatggaaat cccaacaacg ggcgaaacgc tggataacat tgtctgcttc tggcagccag
     2881 aaaaagctgt aaaagcgggt gatgagtttg cattccagta tcgtctgtac tggagtgcgc
     2941 aaccgcctgt tcattgccca ttagcgcgcg ttatggcgac gcgtaccggc atgggtggtt
     3001 tcccggaagg ttgggctcca ggtgaacact atcccgaaaa atgggcgcgt cgttttgccg
     3061 tcgatttagt tggtggtgat ctgaaagctg ccgcgccaaa aggcattgag ccggtgatta
     3121 cgctttccag tggggaagcg aagcaaatcg aaattctcta tattgaaccc attgatggtt
     3181 atcgtattca gtttgactgg tatccgactt cggactccac tgatccggtc gatatgcgga
     3241 tgtatctgcg ttgtcagggc gacgctatca gtgaaacatg gctgtatcag tatttcccgc
     3301 cagcgcccga taaacgtcag tatgttgacg accgcgtgat gagttaatcg ttttttcttc
     3361 ggcaccttct tcgggaggtg ccgtctggtt aaacacgatc ccgctcgcat ttttccctaa
     3421 gttaaatgag taatctgatg gtgtgtattt cagatacacc tagtcagcca ctaacaggga
     3481 gtgcgtatgt ttcctgaata tcgagattta atatcccgtc tgaaaaacga aaatcctcgc
     3541 tttatgtcct tgttcgataa acacaataaa cttgatcatg aaattgccag aaaggaaggt
     3601 tccgacggtc gagggtacaa tgcggaagtg gtccgcatga aaaaacaaaa gctacagtta
     3661 aaagatgaga tgctcaaaat cctgcagcag gagagcgtca aagaggtgta aactttccta
     3721 agccgccagc caggcggctt ttttaacaac tgcatggatt gactggagat aagatgaccg
     3781 aaacgataaa agtaagtgaa tcacttgaat tacatgctgt tgcagaaagt catgtcacac
     3841 ctctttatct gttaatctgt aaaaatagaa cctggctaca gcagtcgcta aactggccgc
     3901 agtttgttca aagtgaagag gacacgcgaa aaacggtgca gggcaatgta atgttgcatc
     3961 aacgcggata tgccaaaatg ttcatgattt tcaaagaaga tgaacttatc ggcgttatct
     4021 cgtttaatcg tattgaacca ctgaataaaa ccgctgaaat cggctactgg ctggacgaat
     4081 ctcatcaggg gcaggggatc atttctcagg cgctgcaggc attgattcat cattacgctc
     4141 agtctggtga acttagacgc ttcgtgatca aatgtcgggt ggacaatccg caaagcaacc
     4201 aggtcgcttt gcgcaatggt tttatccttg aaggttgcct gaaacaggct gagttcctga
     4261 atgatgccta tgatgatgtg aacttatacg cgcgtattat cgattcacaa taaccctgcc
     4321 agcggcgttc gagtaatgcg ctcctcgccg ttaatgactt ttggaccacg gacatgaacc
     4381 gtgtcgccat caaaggcttc aacgacggcg tggtcggtta actccacatg gttttcaatt
     4441 atcaccgcac ctgtaatacg gctctcacct tgtatgacaa cgtgctcgtc gagcagaatc
     4501 ggtccgccac gtaccacggc atttccgcca atcaagacat gatgttttaa cacacaatta
     4561 ccttccacaa tggcatattc cgccacctgc gaactgtaat gaatcgtcgg aatggcatct
     4621 tcttctatgc cagctttcac ctgcgcgtga ccgcagactt tagcacaatc gcatagccag
     4681 acgttgttct cctcattacc ttcaatactg gcaaaatcaa aaacttcggc gcgatgttca
     4741 ataaaagcat accggacgac ggcatcgcca taaatttgtg cctggtggac aatccgcgag
     4801 gcgctaaccc tcgcgcgatc ataaatttgt agcaggagtt gatggtcggg cgttaagcct
     4861 tgtgcggcga cgatcataga atgttgatca attaaggcgt gaccaaatat tctacattga
     4921 ccgcaaacta atgagccacg aatggtgaca ctgtcactta tatgtgcacc ctggctgatt
     4981 tcactattat cgatccagac gttatccgtt gcgtaaacct ctccccacag cacgctggtg
     5041 ccggtgatac gcgtattacc ggaaatcacc gttccgccga acgcaatagc attctggtcg
     5101 taaatccagc aatttccttc ctgtgctaac accgtttcgc gatcgatcca gccgccagcg
     5161 cttcctgcta tcacatcgtt aaaatcgcta atggcgataa tctgccgtaa taacacattt
     5221 tttttagtgc catcttcctg ataactaaag gctcgctgtt cttcacttag acgatatttg
     5281 cgcatagcgt tttcccacag gtgacttact ataaccgtag caaattctgc ggctctggct
     5341 atgctcgaga aaattccata aaatgcattt caaatatact ttataaatta aacaaaatga
     5401 gtaagaagat gcagagcgat aaagtgctca atttgccggc aggctacttt agtattgtgt
     5461 tggggacgat agggatggga tttgcctggc gctatgccag ccaggtttgg caggtcagcc
     5521 actggttggg ggatgggctg gtgattctgg cgatgatcat ctggggatta ttgactggcg
     5581 catttattac ccgactcata cgctttccgc atagcgtgct ggcagaagtg cgccatccag
     5641 tgctgagcag ttttgtgagt ttgtttccgg caacgacgat gctggtggcg attggttttg
     5701 ttccgtggtt tcgcccactg gcggtgtgcc tgttcagttt tggtgtcgtg gttcagttgg
     5761 cttatgccgc ctggcaaact gcgggattat ggcgcggatc tcaccctgaa gaagctacca
     5821 cgcctggact gtatctgccg acagttgcca acaactttat cagcgcaatg gcctgtggtg
     5881 cgttgggcta caccgacgcc ggtctggtgt ttttaggcgc aggcgttttc tcatggctaa
     5941 gcctggaacc ggtgatcttg cagcgtctgc gcagttcggg agaattaccc acggcgctgc
     6001 ggacatcact cggcattcag ctcgctcctg cgctggtggc ctgtagtgcc tggctgagcg
     6061 tcaacggcgg cgagggtgac acgctggcga aaatgctttt cggttatgga ctgctgcaac
     6121 tgctgtttat gctacgtctg atgccatggt atctctccca gccatttaat gcttcattct
     6181 ggagtttctc gttcggcgta tctgcactgg caaccaccgg tttgcatctg gggattggca
     6241 gcgataatgg atttttccat acgctggcgg tgccgctgtt tatctttacc aattttatta
     6301 ttgcaatact gctcatccgt acttttgcgc ttctgatgca gggaaaattg ttaatcagaa
     6361 ccgagcgcgc cgttttaatg aaagcagagg acaaagaatg atcattcgtg acgaaaacta
     6421 ttttactgat aaatatgaat taacccgcac acactctgaa gtgctggaag cggtgaaagt
     6481 ggttaaaccg ggtaaaacgc tggatctggg ctgtggcaat ggtcgtaaca gtctttacct
     6541 ggcagccaat ggttatgatg ttgacgcatg ggataaaaat gccatgagta tcgccaacgt
     6601 cgagcgcatt aagtccattg aaaatctgga taatttacac acccgggtcg ttgatctgaa
     6661 taacctcaca tttgatggac agtacgattt tattctttcg actgtggtgc tgatgttcct
     6721 tgaggctaaa accatcccag ggctgattgc caatatgcaa cgttgcacta aacctggcgg
     6781 ttacaacctg attgtggcgg cgatggatac cgctgattat ccatgtaccg tcggcttccc
     6841 gtttgccttc aaagagggag aattacgtcg atattacgaa ggctgggaga gggtgaaata
     6901 caatgaagac gtcggcgagc tgcaccgcac cgacgccaac ggtaatcgta ttaaactgcg
     6961 tttcgccacg atgctggcac gtaaaaaatg acccgctaag aacaaggcgc gtgaaaattc
     7021 cccccgctga gatggtttac tgttcttctt ttcggtaagc ataattttta tcgaagggat
     7081 gtgaaattaa tcacagtagt cgaagttttt tagcagctta acttactgaa atttaactac
     7141 tgatgattga cttagcccct ttttcggcat tgactatgtc gtctgtaaag gggctgaaaa
     7201 atttattttc accaacactt tttttgccac aacacgaagc ggcgcttttt gctataactt
     7261 aaaaagtaat ataatcatct caggaaacta ttcatgcgta ccacatcaat tgcgaaagtt
     7321 gcagctttat gcggcttgtt ggctctgtct ggttgtgcct ctaaaatcac ccagccagat
     7381 aaatattctg gttttttaaa caattactct gatttaaaag aaacaaattc tgcaacgggt
     7441 aaacctgttt tacgttgggt agacccgagt tttgatcaaa gcaaatatga cagcatcgtc
     7501 tggaacccaa tcacttatta tccggtaccg aaaccttcaa cccaggtagg gcagaaagtt
     7561 ctggataaaa ttttgaacta taccaacacc gaaatgaaag aagcgatagc gcagcgtaaa
     7621 ccactggtta ccaccgctgg gccgcgtagt ctgattttcc gtggggccat taccggtgta
     7681 gataccagca aagaagggct gcaattctat gaagtggttc ctgttgcatt agtggttgcg
     7741 gggacgcaaa tggctacagg ccaccgtacc atggatactc gcttgtattt tgaaggtgag
     7801 ctgattgatg cagcgactaa taaaccggtt atcaaagtcg ttcgtcagg
//
LOCUS       DADXDL010000145         7784 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.145, whole genome shotgun sequence.
ACCESSION   DADXDL010000145 DADXDL010000000
VERSION     DADXDL010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7784
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.145"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..861
                     /locus_tag="IRB70_004484"
     CDS             <1..861
                     /locus_tag="IRB70_004484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HBC0634321.1"
                     /translation="VCQDIGSESNIFADWAASRQGCTVGGQSSSVRDKASDKDKERVL
                     KNQNIIWEALKKNRMFDGNKELKEFIMTLTGTLIFGEDSEITPLPARTTDRDILRAIM
                     EGGTAKIYHCNDSDKCLKVVADANVTIARDKALKSQITKLLTSIQNKAVSDTPLDARE
                     QGFISSTTIPVFKYLIDPQMLGVSNSVVYQLTDYIGYDIMLQYIQELLQQARAMIATG
                     NYPQAVMDNVLENLNQAQQQIAIFQSQVQVQQDALLVVERQMSYMRQQLSARMLSRYQ
                     NNYHFGGNSL"
     gene            858..3677
                     /gene="traG"
                     /locus_tag="IRB70_004485"
     CDS             858..3677
                     /gene="traG"
                     /locus_tag="IRB70_004485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer mating pair stabilization
                     protein TraG"
                     /protein_id="HBC0634322.1"
                     /translation="MNEVYVIAGGEWLRNNLNAIAAFMSTRTWDSIEKIALTLSVLAV
                     AVMWVQRHNVMDLLGWVAVFVLISLLVNVRTSVQIIDNSDLVKVHRVDNVPVGLAMPL
                     SLTTRIGHAMVVSYEMIFTQPDSVTYSKTGMLFGANLIVKSTDFLSRNPEIINLFQDY
                     VQNCVLGDIYLNHKYTLEDLMASADPYTLIFSRPSPLRGVYDNNNNFITCKDASVTLK
                     DRLNLDTKTGGKTWHYYVQQIFGGRPDPDLLFRQLVSDSYSYFYGSSQSASQIMRQNV
                     TINALKEGITSNAARNGDTASLVNLATTSSMEKQRLAHVSIGHVTMRNLPMVQTILTG
                     IAIGIFPLLVLAAVFNKLTLSVLKGYVFALMWLQTWPLLYAILNSAMTFYAKMNGAPV
                     VLSELSQIQLKYSDLASTAGYLSAMIPPLSWMMVKGLGAGFSSVYSHFASSSISPTAS
                     AAGSVVDGNYSYGNMQTENVNGFSWSTNSTTSFGQMMYQTGSGATATQTRDGNMVMDA
                     SGAMSRLPVGINATRQIAAAQQEMAREASNRAESALHGFSSSIASAWNTLSQFGSNRG
                     SSDSVTGGADSTMSAQDSMMASRMRSAMESYAKAHNISNEQATQELASRSTRASAGMY
                     GDAHAEWGVKPKILGVGGGLGVRGGGRAGIDWSDDDAHQASSGSRASNDARHDIDARA
                     TQDFKEASDYFTSRKVSESGSHTDNNADSRVDQLSAALNSAKQSYDQYTTNMTRSHEY
                     AEMASRTESMSGQMSEDLSQQFAQYVMKHAPQDAEAILTNTSSPEIAERRRAMAWSFV
                     QEQIQPGVDNAWRESRGDIGKGMESVPSGGGSQDIIADHQGHQAIIEQRTQDSNIRND
                     VKHQVDNMVTEYKGNIGDTQNSIRGEENIVRGQYSELQNHHKTEALSQNNKYNEEKSV
                     QERMPGADSPQELMKRAKEYQDKYK"
     gene            3696..4193
                     /locus_tag="IRB70_004486"
     CDS             3696..4193
                     /locus_tag="IRB70_004486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000605858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="entry exclusion protein"
                     /protein_id="HBC0634323.1"
                     /translation="MIMRCLAHIALVTVIQFIACYLVGWGKAETVFMLFFIVLWQGLF
                     IWLFSQIRKKRNVSDEFKFSKGVWYITMPVSSLLSPLLSLMVFIIGTLYELRRVSGCI
                     SIKKWGQNQLKNQYDGSEKLDFGGIEQPPTTYYNPSTGYPMHGGFDSAGNTFGTRWQD
                     YYDRQ"
     gene            4225..4956
                     /locus_tag="IRB70_004487"
     CDS             4225..4956
                     /locus_tag="IRB70_004487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="complement resistance protein TraT"
                     /protein_id="HBC0634324.1"
                     /translation="MKTKKLMMVALVSSTLALSGCGAMSTAIKKRNLEVKTQMSETIW
                     LKPDSERTVFLQIKNTSDKDMSGLQGKIADAVKAKGYQVVTSPDKAYYWIQANVLKAD
                     KMDLRESQGWLNRGYEGAAVGAALGAGITGYNSNSAGATLGVGLAAGLVGMAADAMVE
                     DVNYTMITDVQIAERTKATVTTDNVAALRQGTSGAKIQTSTETGNQHKYQTRVVSNAN
                     KVNLKFEEAKPVLEDQLAKSIANIL"
     gene            5159..5938
                     /locus_tag="IRB70_004488"
     CDS             5159..5938
                     /locus_tag="IRB70_004488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000199914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634325.1"
                     /translation="MTSDNIAEYVGENNQFTEKPVTEYPPVIQDNTVTTKDYLYSNNI
                     DTDLLVVIGGLIVILFLMMLIMYFINSLRHKKLTEILGKISFPEKSGSNLLKPEAVSC
                     NLLSLCVLAPVLCTPRKLAEVSREIIVASAQEIAWTPGSSRIDGHQGENITWSLSSQS
                     PADKYDLINKTSRVSPDSGRFYEPDTVLDHRERVRLFIQIQFPHGSDWSEVLRLTDIV
                     TEKVSSGRAAGGYHHRHTGYTWSVSHIILFCPVPDFPGVSS"
     gene            5935..>7784
                     /gene="traD"
                     /locus_tag="IRB70_004489"
     CDS             5935..>7784
                     /gene="traD"
                     /locus_tag="IRB70_004489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001577029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV conjugative transfer system coupling
                     protein TraD"
                     /protein_id="HBC0634326.1"
                     /translation="MSFNAKDMTQGGQIASMRIRMFSQIANIMLYCLFIFFWILVGLI
                     LWVKISWQTFVNGCIYWWCTTLEGMRDLIKSQPVYEIQYYGKTFRMNAAQVLHDKYMI
                     WCGEQLWSAFVLASVVALVICLITFFVVSWILGRQGKQQSENEVTGGRQLTDNPKDVA
                     RMLKKDGKDSDIRIGDLPIIRDSEIQNFCLHGTVGAGKSEVIRRLANYARQRGDMVVI
                     YDRSGEFVKSYYDPSIDKILNPLDARCAAWDLWKECLTQPDFDNTANTLIPMGTKEDP
                     FWQGSGRTIFAEAAYLMRNDPNRSYSKLVDTLLSIKIEKLRTFLRNSPAANLVEEKIE
                     KTAISIRAVLTNYVKAIRYLQGIEHNGEPFTIRDWMRGVREDQKNGWLFISSNADTHA
                     SLKPVISMWLSIAIRGLLAMGENRNRRVWFFCDELPTLHKLPDLVEILPEARKFGGCY
                     VFGIQSYAQLEDIYGEKAAATLFDVMNTRAFFRSPSHKIAEFAAGEIGEKEHLKASEQ
                     YSYGADPVRDGVSTGKDMERQTLVSYSDIQSLPDLTCYVTLPGPYPAVKLSLKYQARP
                     KVAPEFIPRDINPEMENRLSAVLAAREAEGRQMASLFEPEVASGEGVTQA"
BASE COUNT         2005 a         1786 c         2102 g         1891 t
ORIGIN      
        1 gtttgtcagg acattggcag tgaaagcaat atcttcgccg actgggccgc atctcgtcag
       61 gggtgcacgg tcggagggca gtcctcatct gttcgtgaca aagccagcga caaggacaag
      121 gagcgggtgc tgaaaaacca gaatatcata tgggaggcgc tgaaaaaaaa cagaatgttt
      181 gacggcaaca aagagttgaa agaatttatc atgacgctca ccggtacgct gatttttggg
      241 gaagacagcg agattacccc cctgccggcg cgtaccactg accgcgatat cctccgggcg
      301 attatggagg ggggaacggc aaaaatttac cactgcaacg attcggacaa gtgtctgaag
      361 gtggtggcgg atgcaaatgt gaccatcgcc cgggataaag ccctgaagtc acagattaca
      421 aaactgctca ccagtattca gaataaagca gtgagtgaca ctccgcttga cgcccgggaa
      481 caggggttta tttccagcac caccattccc gtttttaaat atctgattga cccgcagatg
      541 ctcggtgtgt ccaacagcgt cgtttaccag ctgacggact atatcggcta cgacatcatg
      601 ctccagtaca ttcaggaact gcttcagcag gcccgggcca tgattgccac cgggaactat
      661 ccgcaggctg tgatggacaa tgttctggag aatctgaatc aggcacagca acagattgcc
      721 attttccaga gccaggtaca ggtccagcag gatgcgctgc tggttgtcga acgtcagatg
      781 agctacatgc gccagcagct ttccgcccgt atgctcagcc gttaccagaa caactatcac
      841 ttcggaggga attcactgtg aatgaagttt atgtgattgc cggtggtgag tggttgcgga
      901 ataacctgaa cgccattgcg gcatttatga gtacgcggac ctgggattcc atcgaaaaaa
      961 ttgcgctcac attgtctgtt ctcgcggtgg ccgtgatgtg ggtacagcgg cacaacgtga
     1021 tggatttgct gggctgggtg gccgtgtttg tgcttatcag cctgctggtt aatgtccgta
     1081 catcggtgca gattattgat aacagtgacc tggtcaaagt ccatcgggtg gataatgtgc
     1141 cggtcggtct ggcgatgcca ctttcactga cgacacgtat cgggcatgca atggtggtca
     1201 gctacgagat gatattcacc caaccggaca gcgtcaccta cagcaagaca ggcatgctgt
     1261 tcggggcgaa tctgattgtg aaaagcaccg atttcctgtc ccggaatccg gaaatcatca
     1321 atctgttcca ggactacgtc cagaactgcg tgctgggtga tatttacctg aatcataaat
     1381 acacgctgga agatctgatg gcctccgctg acccctacac gctgattttt tcccgaccca
     1441 gcccgctacg gggcgtttat gacaacaata ataatttcat aacctgtaag gatgcgtcgg
     1501 tcacgctgaa agacaggctg aatctcgata caaagacggg aggcaagacc tggcattatt
     1561 atgtgcagca gatatttggc ggcagaccgg acccggacct gttattcaga caactggtca
     1621 gtgacagtta cagttatttc tacggctcca gtcagtctgc cagccagatt atgcgccaga
     1681 acgtcacaat aaatgccctg aaagagggta tcaccagtaa tgccgcccgt aatggtgaca
     1741 ccgccagcct ggtgaatctg gccaccacgt catcgatgga gaagcaacgt ctggcgcatg
     1801 tctctatcgg tcatgtgaca atgcgaaacc tgccaatggt acagactatc ctgacgggaa
     1861 ttgccattgg tattttcccg cttctggtac tggcagctgt cttcaacaaa ctgacactgt
     1921 ccgtcctgaa aggctatgtg tttgccctga tgtggctgca gacctggccg ttgttgtatg
     1981 ccattctgaa cagtgccatg acattctatg cgaagatgaa tggtgcgccg gtcgtgctgt
     2041 ctgaactctc tcagatacag ctgaaatact ctgacctggc ctctactgcc gggtatcttt
     2101 cagccatgat ccccccgttg tcatggatga tggtaaaagg ccttggcgca ggtttttcca
     2161 gcgtgtacag ccacttcgcc tcttcctcta tcagtccgac ggccagtgca gcaggcagtg
     2221 tggttgacgg taattactcc tacggcaaca tgcagacgga aaacgtgaac ggcttcagct
     2281 ggagcaccaa cagcaccacg tcgtttggtc agatgatgta ccagaccggc agtggcgcaa
     2341 ctgccacaca gacccgtgac ggtaatatgg tgatggatgc aagcggagcg atgtcccggt
     2401 taccggttgg tatcaatgca acgcgtcaga ttgcagcggc acaacaggaa atggcccggg
     2461 aggcgtcgaa cagagcagaa agtgccctgc atggtttcag cagcagtatt gccagtgcct
     2521 ggaacacgct cagtcagttt ggttctaacc gggggagcag tgattctgtc accggtggcg
     2581 ctgacagcac catgagtgca caggattcca tgatggccag ccgtatgcgc agtgcaatgg
     2641 aaagctatgc gaaggcgcat aatatcagta atgagcaggc gactcaggaa ctggcatcca
     2701 gaagtacgag agcttctgcc gggatgtatg gcgatgctca tgctgaatgg ggggttaaac
     2761 ctaaaattct tggtgttggt ggaggattag gcgttagagg cggtggtcgg gctggcattg
     2821 actggagtga tgatgatgcg catcaggcca gcagtggttc acgggccagc aatgatgctc
     2881 gtcatgatat cgatgccaga gctacacaag actttaaaga ggccagcgat tactttacca
     2941 gtcgcaaggt cagtgagtcc ggcagccata ctgacaataa tgctgattcc cgtgtggatc
     3001 agttgtctgc agccctgaat tcagcgaagc agagttacga ccagtacacg acgaatatga
     3061 ctcgcagcca tgaatatgct gaaatggcat cccgtactga aagcatgagt gggcagatga
     3121 gtgaagactt gtcgcaacag tttgcacagt atgtaatgaa acacgcgcca caggatgcag
     3181 aagctattct gacaaatacc agttcaccgg agattgcaga acgccgtcgg gcgatggcct
     3241 ggtcttttgt gcaggaacag atacagcctg gtgttgataa tgcctggcgg gaatcccgtg
     3301 gcgatattgg taaaggaatg gagagcgtac cttcgggtgg tggcagtcag gatattattg
     3361 ctgaccatca gggacatcag gccattattg agcaaagaac gcaggacagt aatatccgta
     3421 atgatgtaaa acatcaggtt gataatatgg tcacagaata taaagggaat ataggtgata
     3481 ctcagaacag catacgtggc gaggaaaata ttgtaagagg acagtattct gaactacaga
     3541 atcaccataa aacagaggca ttatctcaga ataataaata taatgaagaa aagtcggttc
     3601 aggaaagaat gcccggggct gacagtccac aggaactgat gaaaagggca aaggagtatc
     3661 aggataagta taagtaataa tgctgtgttt gggagatgat aatgagatgt ctagcccata
     3721 ttgctctggt aacggtgata cagtttatcg cctgctatct ggttggttgg gggaaggccg
     3781 aaacagtttt tatgctgttc ttcatagtgc tatggcaggg actgtttata tggttgttct
     3841 ctcaaatacg aaaaaaacgg aatgtgtcgg atgagtttaa attcagtaaa ggcgtttggt
     3901 atataacgat gccagtatct tccttactct ctccgttatt aagcctgatg gtttttatca
     3961 ttggtacact atacgaatta aggcgagtta gtggttgcat aagcataaaa aaatggggtc
     4021 aaaatcaact caaaaaccaa tatgatggga gtgaaaagtt agacttcggg ggcattgaac
     4081 agcccccaac gacctactat aacccttcaa ccggatatcc tatgcatgga ggctttgact
     4141 cagcgggaaa tacttttggg actcgttggc aggattatta tgacaggcaa taagaaaact
     4201 gtagtttgta aaaaaggtaa tttgatgaaa acaaaaaaat taatgatggt tgcactggtc
     4261 agttccactc tggccctttc agggtgtggt gcgatgagca cagcaatcaa gaagcgtaac
     4321 cttgaggtga agactcagat gagtgagacc atctggctta aacccgacag cgaacgcacg
     4381 gtatttctgc agatcaaaaa cacgtctgat aaagacatga gtgggctgca gggcaaaatt
     4441 gctgatgctg tgaaagcaaa aggatatcag gtggtgactt ctccggataa agcctactac
     4501 tggattcagg cgaatgtgct gaaggctgat aagatggatc tgcgggagtc tcagggatgg
     4561 ctgaaccgtg gttatgaagg cgcagctgtt ggtgcagcgt taggtgccgg tattaccggc
     4621 tataactcaa attctgccgg tgccacactc ggtgtgggcc ttgctgctgg tctggtgggt
     4681 atggctgcag atgcgatggt ggaagatgtg aactatacca tgatcacgga tgtgcagatt
     4741 gcagagcgta ctaaggcaac ggtgacaacg gataatgttg ccgccctgcg tcagggcaca
     4801 tccggtgcga aaattcagac cagtactgaa acgggtaacc agcataaata ccagacccgt
     4861 gtggtctcaa atgcgaacaa ggttaacctg aaatttgaag aggcgaagcc tgttctcgaa
     4921 gaccagctgg ccaaatcaat cgcaaatatt ctctgattat cttccggagg ctggtctgac
     4981 cggcctcctg actgacgcct cgctttgctc gttgtccaac cccggaaaga aataaaataa
     5041 attttatttc tccccggcgt ttccgaaata aatatgaaaa cactgagcgg ttgtgcaaat
     5101 tctttgtgcg accgtgaagt gttgccggcg aagccgggat cttccggaga aagtcattat
     5161 gacatcagac aatatcgctg aatatgttgg tgagaataat caatttactg agaagcctgt
     5221 aactgaatac cccccggtga tacaggataa tacagtgacc actaaagact atctgtacag
     5281 caataatatt gatactgacc ttttagtggt tatcggaggg cttattgtta tattgtttct
     5341 catgatgctt atcatgtact ttattaattc tctcaggcat aagaaattaa ctgaaatact
     5401 gggaaaaata tcttttcctg aaaaatccgg gagcaatttg cttaaaccgg aggcggtcag
     5461 ctgtaatttg ttgtccctgt gtgtgctggc accggtactc tgtacaccca gaaagctggc
     5521 agaagtctcc agggagatca tcgtggcgag tgcgcaggaa attgcatgga cgccggggag
     5581 cagtcgtatt gatggtcatc agggcgaaaa tattacctgg tctctgtcat cgcagtctcc
     5641 tgccgataag tatgatctca tcaataaaac gtcccgtgtt tctcctgaca gtggccgttt
     5701 ttatgaaccg gacacagttc tggatcaccg tgaacgggta cgccttttta ttcagatcca
     5761 gtttccgcac gggagtgact ggtctgaagt attgcgcctg actgacattg ttacagagaa
     5821 ggtctcttcc ggcagggctg caggcgggta tcaccaccgg catacagggt acacctggtc
     5881 tgtttcccac atcatccttt tctgccctgt tccagatttt cccggagttt catcatgagt
     5941 tttaacgcaa aggatatgac ccagggcggt cagattgcgt ccatgcgtat ccgcatgttc
     6001 agccagatcg ccaatatcat gctttactgc ctgtttattt ttttctggat actcgttggt
     6061 ctgattttat gggtaaaaat aagctggcag acgtttgtga acggctgtat ttactggtgg
     6121 tgtaccacgc tggaaggcat gcgggattta atcaagtccc agccagtata tgagattcag
     6181 tattacggca aaaccttccg gatgaacgct gcccaggtac tgcatgataa atatatgatc
     6241 tggtgcggtg agcagctatg gtccgcattc gttctggcgt ctgtcgtggc cctggttatt
     6301 tgcctgatca ccttctttgt tgtctcctgg attctggggc gtcagggtaa acaacagagc
     6361 gaaaatgaag tcacaggtgg tcgtcagctg acagacaatc cgaaagacgt tgcccggatg
     6421 ctgaaaaaag acggcaagga ctccgatatc cggattggcg acctgccgat tatccgggat
     6481 tccgaaatcc agaacttctg tctgcacggc acggtcgggg ccggtaagtc ggaggttatc
     6541 cgtcgtctgg ccaactatgc ccgtcagcgc ggtgatatgg tggtgattta tgaccgttca
     6601 ggggaatttg ttaaaagtta ctatgatccc tccatcgata aaatcctgaa tccgctggat
     6661 gcccgctgtg ccgcatggga tttgtggaag gagtgcctga cacagccgga ttttgataat
     6721 accgcaaata ctctgatccc tatgggtaca aaagaggacc cgttctggca gggttcagga
     6781 cgtaccattt ttgcggaagc ggcgtacctg atgcgtaatg accccaaccg cagctacagc
     6841 aaactggtgg acacactgct ttccatcaaa attgaaaaac tgcgtacctt cctgcgtaat
     6901 tcaccggcgg ccaacctggt ggaagagaaa attgagaaaa cggcgatttc catccgtgct
     6961 gtgctgacca actacgtgaa agccatccgt tacctgcagg ggattgagca taacggtgag
     7021 cccttcacca tccgtgactg gatgcgtggt gtccgggaag atcagaaaaa cggctggctg
     7081 tttatttcgt cgaacgccga cacccatgcc tccctgaagc ctgtgatctc catgtggctg
     7141 tccattgcca ttcgtggtct gctggcaatg ggagaaaacc gtaaccgtcg tgtgtggttt
     7201 ttctgtgatg agttacccac gttacacaaa ctgccggacc tggtggagat cctgccggaa
     7261 gcccgtaagt tcggtggctg ttatgtgttt ggtatccagt cctatgccca gctggaagat
     7321 atctacggtg agaaagcggc ggccacgctg tttgacgtca tgaacacccg tgcttttttc
     7381 cgttccccga gccataagat tgcagagttc gctgccggtg agattggtga gaaagagcac
     7441 ctgaaagcca gcgagcagta ttcctacggt gctgacccgg tacgtgacgg ggtatcgacc
     7501 ggtaaggata tggagcgtca gacactggtc agttattccg acattcagtc tctgccggat
     7561 ctgacctgct atgtcactct gcccggaccg tatccggcag taaaactctc cctgaaatat
     7621 caggcacgac cgaaggtcgc tccggagttt attccgcgtg acatcaaccc ggaaatggag
     7681 aaccgtctga gtgccgtact tgctgcaagg gaagcagaag gtcgccagat ggccagcctc
     7741 ttcgaaccgg aggttgcctc cggagaaggc gtgactcagg ctga
//
LOCUS       DADXDL010000146         7781 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.146, whole genome shotgun sequence.
ACCESSION   DADXDL010000146 DADXDL010000000
VERSION     DADXDL010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7781)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7781)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7781
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.146"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..222
                     /locus_tag="IRB70_004490"
     CDS             <1..222
                     /locus_tag="IRB70_004490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000622024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634327.1"
                     /translation="ESRLRSSDPAAPAIQAINAFMDKGNHLQDLYSNKSLSKAGLERR
                     NEILRAQVISGLQASEELAKLLIASGVML"
     gene            232..540
                     /locus_tag="IRB70_004491"
     CDS             232..540
                     /locus_tag="IRB70_004491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001607262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634328.1"
                     /translation="MNDVQNRRILALLNMLYYALGNRTTCDICHKYFILVLSVMNNLT
                     INYGSQTSPELTGISYEDANDLITELILFIEDVNADNDMEYPAHLNKIQALLNFAVAN
                     "
     gene            complement(597..1187)
                     /gene="cobO"
                     /locus_tag="IRB70_004492"
     CDS             complement(597..1187)
                     /gene="cobO"
                     /locus_tag="IRB70_004492"
                     /EC_number="2.5.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cob(I)yrinic acid a,c-diamide
                     adenosyltransferase"
                     /protein_id="HBC0634329.1"
                     /translation="MSDERYQQRQQRVKEKVDARVAQAQDERGIIIVFTGNGKGKTTA
                     AFGTATRAVGHGKKVGVVQFIKGTWPNGERNLLEPHGVEFQVMATGFTWDTQNRESDT
                     AACREVWQHAKRMLADPSLDMVLLDELTYMVAYDYLPLEEVVQALNERPHQQTVIITG
                     RGCHRDILELADTVSELRPIKHAFDAGVKAQIGIDY"
     gene            complement(1184..1942)
                     /locus_tag="IRB70_004493"
     CDS             complement(1184..1942)
                     /locus_tag="IRB70_004493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciK family oxidoreductase"
                     /protein_id="HBC0634330.1"
                     /translation="MHYQPKQDLLNDRIILVTGASDGIGREAAMTYARYGATVILLGR
                     NEEKLRQVASHINEETGRQPQWFILDLLTCTSEDCQQLAQRIAVNYPRLDGVLHNAGL
                     LGDVCPMSEQNPQVWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
                     NWGAYAASKFATEGMMQVLADEYQQRLRVNCINPGGTRTAMRASAFPTEDPQKLKTPA
                     DIMPLYLWLMGDDSRRKTGMTFDAQPGRKPGISQ"
     gene            2162..3211
                     /gene="sohB"
                     /locus_tag="IRB70_004494"
     CDS             2162..3211
                     /gene="sohB"
                     /locus_tag="IRB70_004494"
                     /EC_number="3.4.21.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415788.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protease SohB"
                     /protein_id="HBC0634331.1"
                     /translation="MELLSEYGLFLAKIVTVVLAIAAIAAIIVNVAQRNKRQRGELRV
                     NNLSEQYKEMKEELAAALMDTHQQKQWHKAQKKKHKQEAKAAKAKAKLGEVATDSKPR
                     VWVLDFKGSMDAHEVNSLREEITAVLAAFKPQDQVVLRLESPGGMVHGYGLAASQLQR
                     LRDKNIPLTVTVDKVAASGGYMMACVADKIVSAPFAIVGSIGVVAQMPNFNRFLKSKD
                     IDIELHTAGQYKRTLTLLGENTEEGREKFREELNETHQLFKDFVKRMRPSLDIEQVAT
                     GEHWYGQQAVEKGLVDEINTSDEVILSLMEGREVVNVRYMQRKRLIDRFTGSAAESAD
                     RLLLRWWQRGQKPLM"
     gene            complement(3247..3498)
                     /locus_tag="IRB70_004495"
     CDS             complement(3247..3498)
                     /locus_tag="IRB70_004495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YciN family protein"
                     /protein_id="HBC0634332.1"
                     /translation="MNKETQPIDRETLLKEANKIIREHEDTLAGIEATGVTQRNGVLV
                     FTGDYFLDEQGLPTAKSTAVFNMFKHLAHVLSEKYHLVD"
     gene            3878..6475
                     /gene="topA"
                     /locus_tag="IRB70_004496"
     CDS             3878..6475
                     /gene="topA"
                     /locus_tag="IRB70_004496"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000513601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBC0634333.1"
                     /translation="MGKALVIVESPAKAKTINKYLGSDYVVKSSVGHIRDLPTSGSAA
                     KKSADSTSTKTAKKPKKDERGALVNRMGVDPWHNWEAHYEVLPGKEKVVSELKQLAEK
                     ADHIYLATDLDREGEAIAWHLREVIGGDDARYSRVVFNEITKNAIRQAFNKPGELNID
                     RVNAQQARRFMDRVVGYMVSPLLWKKIARGLSAGRVQSVAVRLVVEREREIKAFVPEE
                     FWEVDASTTTPSGEALALQVTHQNDKPFRPVNKEQTQAAVSLLEKARYSVLEREDKPT
                     TSKPGAPFITSTLQQAASTRLGFGVKKTMMMAQRLYEAGYITYMRTDSTNLSQDAVNM
                     VRGYISDNFGKKYLPESPNQYASKENSQEAHEAIRPSDVNVMAESLKDMEADAQKLYQ
                     LIWRQFVACQMTPAKYDSTTLTVGAGDFRLKARGRILRFDGWTKVMPALRKGDEDRIL
                     PAVDKGDALTLVELTPAQHFTKPPARFSEASLVKELEKRGIGRPSTYASIISTIQDRG
                     YVRVENRRFYAEKMGEIVTDRLEENFRELMNYDFTAQMENSLDQVANHEAEWKAVLDH
                     FFSDFTQQLDKAEKDPEEGGMRPNQMVLTSIDCPTCGRKMGIRTASTGVFLGCSGYAL
                     PPKERCKTTINLVPENEVLNVLEGEDAETNALRAKRRCPKCGTAMDSYLIDPKRKLHV
                     CGNNPTCDGYEIEEGEFRIKGYDGPIVECEKCGSEMHLKMGRFGKYMACTNEECKNTR
                     KILRNGEVAPPKEDPVPLPELPCEKSDAYFVLRDGAAGVFLAANTFPKSRETRAPLVE
                     ELYRFRDRLPEKLRYLADAPQQDPEGNKTMVRFSRKTKQQYVSSEKDGKATGWSAFYV
                     DGKWVEGKK"
     gene            6685..7659
                     /gene="cysB"
                     /locus_tag="IRB70_004497"
     CDS             6685..7659
                     /gene="cysB"
                     /locus_tag="IRB70_004497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012017585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator CysB"
                     /protein_id="HBC0634334.1"
                     /translation="MKLQQLRYIVEVVNHNLNVSSTAEGLYTSQPGISKQVRMLEDEL
                     GIQIFSRSGKHLTQVTPAGQEIIRIAREVLSKVDAIKSVAGEHTWPDKGSLYIATTHT
                     QARYALPNVIKGFIERYPRVSLHMHQGSPTQIADAVSKGNADFAIATEALHLYEDLVM
                     LPCYHWNRAIVVTPDHPLAGKKAITIEELAQYPLVTYTFGFTGRSELDTAFNRAGLTP
                     RIVFTATDADVIKTYVRLGLGVGVIASMAVDPVADPDLVRVDAHDIFSHSTTKIGFRR
                     STFLRSYMYDFIQRFAPHLTRDVVDAAVALRSNEEIEAMFKDIKLPEK"
BASE COUNT         2022 a         1828 c         1994 g         1937 t
ORIGIN      
        1 gaaagcagat tgcgttcatc tgatccggcg gctccagcaa tacaagctat taatgccttc
       61 atggataaag gaaatcatct acaagattta tactctaata aatctctttc aaaagcgggt
      121 ttagagcgta ggaatgagat cctgcgtgct caagttatta gtggtcttca ggcgtcagag
      181 gagctggcaa aacttcttat tgccagcgga gttatgttat aggaggtcat tatgaacgat
      241 gtgcaaaatc gacgaatact ggcattgctc aatatgctgt actatgcctt aggaaaccga
      301 acaacttgcg atatatgtca caaatatttt attctggttt tgtcggtaat gaataatctg
      361 acaattaatt atggctcgca aacgtcacca gaactgactg gtattagtta tgaagatgct
      421 aatgatttga tcactgaatt aatactgttt attgaagacg tcaatgcgga taatgacatg
      481 gaatatcccg cacacttgaa taaaattcaa gctcttctta attttgccgt ggctaattaa
      541 gccattcagt atctaaaatt agcacctcaa gaggcgatct tttgaggtgc tttcccttaa
      601 taatcaatcc ctatttgcgc cttaacaccg gcatcaaacg catgtttgat ggggcgcagc
      661 tcacttaccg tatccgccag ttcgagtata tcccgatgac aaccacgacc cgtgataatc
      721 accgtttgtt gatgtggacg ttcatttaac gcctgcacca cttcttccag tggcaaatag
      781 tcatacgcca ccatataagt cagctcatcg agcaaaacca tatccagtga aggatcggcc
      841 agcattcgtt tggcatgttg ccagacttca cggcaggccg cagtatcaga ttcgcgattt
      901 tgtgtatccc aggtaaagcc cgttgccatc acctgaaact caacgccatg tggctccagt
      961 agattgcgct cgccattagg ccaggtgcct ttaataaact gcacgacgcc cacttttttg
     1021 ccatggccta ctgcacgagt tgccgtacca aatgccgcgg tggttttgcc ttttccattg
     1081 ccggtaaaga cgatgataat accgcgttca tcctgggcct gggccacacg agcatcgact
     1141 ttttctttca ctcgctgctg acgctgttgg tagcgttcat cactcattgg gaaattcctg
     1201 gtttacggcc cggttgggcg tcaaaggtca tgccggtttt acggcggctg tcatcgccca
     1261 tcagccagag gtagagcggc atgatatcag cgggtgtttt aagtttctgt ggatcttcgg
     1321 tcgggaaggc gctggcacgc attgcggtgc gcgtaccgcc tgggttaatg cagttgacgc
     1381 gcaggcgctg ctgatattca tcggccagta cctgcatcat cccttcggtg gcaaatttcg
     1441 acgctgcata tgcgccccag ttggctcgtc cctgacgtcc aacgcttgat gaagtaaaga
     1501 ccagtgaacc ggcgtccgat ttgagtaata aaggaagcag tgcctgggtg agcataaagg
     1561 tggcattaac gttgacctgc atgacgtcct gccagacctg cggattttgt tcgctcattg
     1621 ggcaaacatc gccgagcaat ccggcattat gcaaaacacc atccagacgc ggataattaa
     1681 cggcaatgcg ctgtgccagt tgttggcaat cttcggacgt gcaggtcagc aaatcgagaa
     1741 taaaccactg tggctgacgc ccagtttctt cgtttatgtg gctggctacc tgacgtaatt
     1801 tttcttcatt acggcccaac agaatcactg tcgcaccata gcgtgcatac gtcatcgcgg
     1861 cttcacgacc aataccatca ctggctcccg tcaccaggat aatgcgatca ttgagtaaat
     1921 cttgttttgg ctggtaatgc atggctactc ctcaacgacg ttgtctgtcg cgctgccagt
     1981 gttctttatg actttggggc tttatgcctg aaacagaagg gcatttcaat cagcctgggg
     2041 cgataacacc gcaaaatgga tactttgtca tactttcgct gcaataacat ctctgcgaga
     2101 cggcttaaca tgcctgttgt aaactgtgag ccaaagcgtt gtttaaccaa ggtggggact
     2161 cgtggaattg ttgtctgaat atggtttgtt tttggcgaaa atcgttaccg ttgtgctagc
     2221 gattgcggcg attgccgcca ttattgtcaa tgttgctcaa cgtaataaac gccagcgtgg
     2281 cgagttacgg gtcaacaatc tcagcgaaca gtataaggag atgaaagaag aactggccgc
     2341 ggcgctgatg gacactcatc agcaaaaaca gtggcacaaa gcgcagaaga aaaagcacaa
     2401 gcaagaagcg aaagcagcaa aagcgaaagc taaactgggc gaggtggcaa ctgacagtaa
     2461 acctcgcgtc tgggtgctgg attttaaagg cagcatggac gcccatgaag tgaactcgct
     2521 acgtgaagag ataacggcgg tactcgcagc attcaaaccg caggatcagg ttgtgctccg
     2581 tctggaaagc cctggtggca tggtgcatgg ttacgggttg gcggcttcgc agctgcagcg
     2641 tctgcgtgat aaaaacattc ctttaactgt tacggtagac aaagtcgctg ccagcggcgg
     2701 ttacatgatg gcctgtgtgg cggacaaaat tgtttccgca ccgtttgcta ttgtgggttc
     2761 cattggcgtg gtggcacaaa tgcccaactt taaccgcttc ctgaaaagca aagatattga
     2821 tatcgaactg cacaccgccg ggcagtataa gcgcacgctg accttgctgg gtgaaaacac
     2881 cgaagaaggg cgggagaaat tccgcgaaga gctgaacgaa acgcatcagt tatttaaaga
     2941 ttttgtgaag cgtatgcgtc cgtctctgga tattgaacag gtggcaacgg gtgaacactg
     3001 gtacggacaa caggcggtag agaaaggcct ggttgatgaa atcaacacca gtgatgaagt
     3061 tattcttagc ctgatggaag gccgtgaagt ggtcaatgta cgctatatgc agcgtaaacg
     3121 actcattgac cgattcaccg gcagcgcggc agagagcgcc gatcgattgt tgctacgctg
     3181 gtggcagcgg ggtcaaaagc cattgatgta aaagacaaac gcgagggtaa gacctcgcgt
     3241 tttgctttaa tcaaccaggt gatatttttc tgaaagcaca tgggccaggt gtttgaacat
     3301 attaaacacc gcggtgcttt tggctgttgg caatccttgt tcatctaaaa agtagtcgcc
     3361 ggtaaatacc agcacgccat tacgctgcgt gacgccggtg gcttcaatcc ctgcgagcgt
     3421 atcctcatgc tcacgaatga ttttgttggc ctctttcaac agcgtctcgc ggtcgatggg
     3481 ttgtgtctct ttgttcatta tttactcctt aaacaaggac attagtctac gccaggcatg
     3541 gcttgcagac aaatatacca cgctggtggc aagagcgcct tactggcaac tttggatttt
     3601 gcatgctaat aaagttgcgt atcggatttt atcaggtaca gtgtgacgct ttcgtcaatc
     3661 tggcaataga tttgcttgac attcgaccaa aattccgtcg tgctatagcg cctgtaggcc
     3721 aagacctgtt aactcagtca cctgaatttt cgtgaacaga gtcacgacaa ggggttgata
     3781 tccgcagaga gcgagtccat atcggtaact cgttgccagt ggaaggttta tcaacgtgcg
     3841 acgcattcct ggaagaatca aattaggtaa ggtgaatatg ggtaaagctc ttgtcatcgt
     3901 tgagtccccg gcaaaagcca aaacgatcaa caagtatctg ggtagtgact acgtggtgaa
     3961 atccagcgtc ggtcacatcc gcgatttgcc gaccagtggc tcagctgcca aaaagagtgc
     4021 cgactctacc tccaccaaga cggctaaaaa gcctaaaaag gatgaacgtg gcgctctcgt
     4081 caaccgtatg ggggttgacc cgtggcacaa ttgggaggcg cactatgaag tgttgcctgg
     4141 taaagagaag gtcgtctctg aactgaaaca actggctgaa aaagccgacc acatctatct
     4201 cgcaaccgac cttgaccgcg aaggggaagc cattgcatgg cacctgcggg aagtgattgg
     4261 tggtgatgat gcgcgctata gccgagtggt gtttaacgaa attactaaaa acgcgatccg
     4321 ccaggcattt aacaaaccgg gtgagctgaa tattgatcgt gttaatgccc agcaggcgcg
     4381 tcgctttatg gaccgcgtgg tagggtatat ggtttcgccg ctgctgtgga aaaagatcgc
     4441 tcgtggtctg tctgccggtc gtgtgcagtc ggtggcggtt cgcctggtgg tcgagcgtga
     4501 gcgtgaaatt aaagcgttcg tgccggaaga gttctgggaa gtcgatgcca gcacgaccac
     4561 gccatctggt gaagcgttgg cgttacaggt gactcatcag aacgacaaac cgttccgtcc
     4621 ggtcaacaaa gaacaaactc aggctgcggt aagtctgctg gaaaaagcgc gctacagcgt
     4681 gctggaacgt gaagacaaac cgacaaccag taaacctggc gctcctttta ttacctctac
     4741 gctgcaacaa gctgccagca cccgtcttgg atttggcgtg aaaaaaacca tgatgatggc
     4801 gcagcgtttg tatgaagcag gctatatcac ttacatgcgt accgactcca ctaacctgag
     4861 tcaggacgcg gtaaatatgg ttcgcggtta tatcagcgat aattttggta agaaatatct
     4921 gccggaaagt ccgaatcagt acgccagcaa agaaaactca caggaagcgc acgaagcgat
     4981 tcgtccttct gacgtcaatg tgatggcgga atcgctgaag gatatggaag cagatgcgca
     5041 aaaactgtac cagttaatct ggcgtcagtt cgttgcctgc cagatgaccc cagcgaaata
     5101 tgactccacg acgctgaccg ttggtgcggg cgatttccgc ctgaaagcac gcggtcgtat
     5161 tttgcgcttt gatggctgga caaaagtgat gcctgcactg cgtaaaggcg atgaagatcg
     5221 tatcttaccg gcagtcgata aaggcgatgc tctgacgctc gttgaactga caccagccca
     5281 gcactttacc aagcctccag cccgtttcag tgaagcatcg ctggtcaaag agctggaaaa
     5341 acgcggtatc ggtcgtcctt ctacctatgc gtcgatcatt tcgaccattc aggatcgtgg
     5401 ctatgtgcga gtagaaaatc gtcgtttcta tgcggaaaaa atgggcgaaa tcgtcaccga
     5461 tcgcctggaa gagaatttcc gcgagttaat gaactacgac tttactgcgc agatggaaaa
     5521 cagcctcgac caggtggcca atcacgaagc agagtggaaa gctgtactgg atcacttctt
     5581 ctcggatttc actcagcagt tagataaagc tgaaaaagat ccggaagagg gtggtatgcg
     5641 cccgaaccag atggttctga ccagcattga ctgcccgact tgtggtcgca aaatggggat
     5701 tcgcacagcg agcaccgggg tattccttgg ctgttctggt tatgcgctgc cgccgaaaga
     5761 gcgttgcaaa accaccatta acctggtgcc ggaaaacgaa gtgctgaacg tgctggaagg
     5821 cgaagacgct gaaaccaacg cgctgcgcgc aaaacgtcgt tgcccgaaat gcggcacggc
     5881 gatggacagc tatctcatcg atccgaaacg taagttgcat gtctgtggta ataacccaac
     5941 ctgcgacggt tacgagatcg aagagggcga attccgcatt aaaggttatg acggcccgat
     6001 cgttgagtgt gaaaaatgtg gctctgaaat gcacctgaaa atgggccgtt tcggtaaata
     6061 catggcctgc accaacgaag agtgtaaaaa cacacgtaag attttacgta acggcgaagt
     6121 ggcaccaccg aaagaagatc cggtgccatt acctgagctg ccgtgcgaaa aatcagatgc
     6181 ttatttcgtg ctgcgtgacg gtgctgccgg tgtgttcctg gcggccaata ccttcccgaa
     6241 atcgcgtgaa acacgtgcgc cactggtgga agagctttat cgcttccgcg accgtctgcc
     6301 ggaaaaactg cgttatctgg ccgatgcgcc acagcaggat ccggaaggta ataagaccat
     6361 ggttcgcttt agccgtaaaa ccaaacagca atatgtctct tcggaaaaag acggaaaggc
     6421 gactggctgg tcagcatttt atgttgatgg caaatgggtt gaagggaaaa aataaccttt
     6481 aattttgtca ggtttttata aacaaagggt cgcgaaagcg gccctttttt attgcatatt
     6541 attttttctt cacacctata cactaaggct ataaatgata tagtggttat agttagcccc
     6601 ttttttatta ttaaatcgta ttagtcaccc gcctggcgtg acgaaaaaac gatgttctga
     6661 tggcgtctaa gtggatggtt taacatgaaa ttacaacaac ttcgctatat tgttgaggtg
     6721 gtcaatcata acctgaatgt ctcatcaacg gcggaaggac tttacacatc acaacccggg
     6781 atcagtaaac aagtcagaat gctggaagac gagctaggca ttcaaatttt ttcccgaagc
     6841 ggcaagcacc tgacgcaggt aacgccagca ggacaagaaa taattcgtat cgctcgcgaa
     6901 gtcctgtcga aagtcgatgc cataaaatcg gtcgccggag agcacacctg gccggataaa
     6961 ggctcgctgt atatcgccac cacgcatacc caggcacgct acgctttacc aaacgttatc
     7021 aaaggcttta ttgagcgtta tcctcgcgtt tctttgcata tgcaccaggg ctcgccgaca
     7081 caaattgctg atgccgtctc taaaggcaat gccgatttcg ctatcgccac agaagcgctg
     7141 catctgtatg aagatttagt gatgttaccg tgctaccact ggaatcgggc tattgtagtc
     7201 actccggatc acccgctggc aggcaaaaaa gccattacca ttgaagaact ggcgcaatat
     7261 ccgttggtga catatacctt cggctttacc ggacgttcag agctggatac tgcctttaac
     7321 cgcgcagggt taacgccgcg tatcgtcttc acggcaacgg atgctgacgt cattaaaact
     7381 tacgtccggt tagggctggg ggtaggggtc attgccagca tggcggtgga tccggtcgcc
     7441 gatcccgacc ttgtgcgcgt tgatgctcac gatatcttca gccacagtac aaccaaaatt
     7501 ggttttcgcc gtagtacttt tttgcgcagt tatatgtatg attttattca gcgttttgca
     7561 ccgcatttaa cgcgtgatgt cgttgatgcg gctgtcgcat tgcgctctaa tgaagaaatt
     7621 gaggccatgt ttaaagatat aaaactgccg gaaaaataat ttcttgcgtt attttcggca
     7681 ccttttatgt agcgaaggtg ccggaatatg ttctcttttg ttacttattt ctataccgtg
     7741 cacaatattt ttacccctca tatttatagg gtaaattacc t
//
LOCUS       DADXDL010000147         7673 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.147, whole genome shotgun sequence.
ACCESSION   DADXDL010000147 DADXDL010000000
VERSION     DADXDL010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7673)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7673)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7673
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.147"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..4439)
                     /gene="air"
                     /locus_tag="IRB70_004498"
     CDS             complement(<1..4439)
                     /gene="air"
                     /locus_tag="IRB70_004498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter adhesin EaeX/Air"
                     /protein_id="HBC0634335.1"
                     /translation="MAGKAHGNGDRRGDNTICGLGDRLRRLTAGICLITQTIFPVMAA
                     APTHINPAHSDTAASLILPNVKTIPYTLGALESPPTVAARFGITVDELRRLNQFRTFA
                     RGFDNVRQGDEIDVPLINSNSPEARNLKAMQMERDGKDPQMQVAEVAQQSGTLLARDM
                     DSEQAASMARGWVASSASAQATDWLSRWGTARVSLGVDEDFSLKSSSFEFLHPWYETP
                     DNLVFSQHTLHRTDDRTQTNHGIGWRYFTSSWMSGVNMFIDHDLTRYHTRTGMGVEYW
                     RDYLKLSGNGYLRLSNWRSAPELDNDYEARPANGWDLRAEGWLPAWPQLGGKLVYEQY
                     YGDEVALFGKDERQNDPHAITAGLSYTPVPLISFSAEQRQGKQGENDTRIGMELTLQP
                     GHSLQKQLDPAEVAARRSLVGSRYDLVDRNNNIVLEYRKKELVRLTLTDPLKGKPGEV
                     KSLVSSLQTKYALKGYDIEAASLQSAGGKVAVSGKDIQVTIPPYRFTAMPETDNTYPI
                     AVTAEDSKGNFSRREESMVVVEKPTLSLADSTLSVDQQILLADGKSTSTLTYTARDSS
                     GKPIPGMTLKTQVKGLQDFALSEWKDNGNGTYTQIVTAGKTSGALSLMPQFNGDDIAK
                     TPALIAIVANTASRADSTIETDQDNYVAGKPIVVKVTLRDDNGNGVTGRKELLKQTVK
                     VDNTKADAVSAWTEESEGIYKASYTAHLIGDKLTAQLTMPGWQTKHSDAFSIAGDKDT
                     AKIAAMQITANNAVARRDHNTVAVTVRDVHQNLLQGQNVTFTVVNGAAVFADPNGGIV
                     TTDKDGIASVNLASDQAVNSLIKAEINGSSQSVEVSFITGDISQLTSTIKTDDVSYTA
                     GGKIKVSVTLMDEQKNLVKGMASLLAGSSVVEVSGTDKNETGNWSEESDGVYTTTRTA
                     KIAGDRHYATLKLSTWSSAQQSDAYAIRESGAVLAYSSIVTDKTAYTAGGAIKVTVTL
                     KDSYENLVGGQRDAINLAIQLPNTKAESIAWNEDQKGIYTATYTALLPGTGLKAQLQM
                     SGWANALTSNDYSISGDAASAQIVAMQVTTGNPDVLANGSDRHTVNVRVEDQFGNVLP
                     EQTVTFTVTKGAAVFANAGQSADIRTDAHGMAEVDLSSTVADASTVEAKINQSSDSKT
                     VNFIADVSTAQVAELVVTQDGSVADGATANTLRARVTDAFGNALAGQTVSVLAGNGAT
                     TAPTVTTQPDGTVEISVTSQTAGTSAVTASINNSSQSRNVTFIADVSTAQIADLVVSQ
                     DNAVADGATANTLQVRVTDAFGNALAGQTVSVLADNGATVAPVVTTQPDGTVEISVTS
                     QTAGSSAVTVSINSSSQSRDVTFIADVRTAKIADLVVTRDNSVADGAMANTLRARVTD
                     AFGNALAGQTVSVTAGNGATVAPVVTTQPDGTVEISVTSQTAGVSAVTATINSSTQSQ
                     NVTFIADVRTAKIADLVVIKDDSVADGAMANTLRVKVTDAFGNA"
     gene            complement(4641..5825)
                     /gene="nepI"
                     /locus_tag="IRB70_004499"
     CDS             complement(4641..5825)
                     /gene="nepI"
                     /locus_tag="IRB70_004499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418118.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine ribonucleoside efflux pump NepI"
                     /protein_id="HBC0634336.1"
                     /translation="MSEFIAENRGADAITRPNWSAVFSVAFCVACLIIVEFLPVSLLT
                     PMAQDLGISEGVAGQSVTVTAFVAMFASLFITQTIQATDRRYVVILFAVLLTLSCLLV
                     SFANSFSLLLIGRACLGLALGGFWAMSASLTMRLVPPRTVPKALSVIFGAVSIALVIA
                     APLGSFLGELIGWRNVFNAAAVMGVLCIFWIIKSLPSLPGEPSHQKQNTFRLLQRPGV
                     MAGMIAIFMSFAGQFAFFTYIRPVYMNLAGFGVDGLTLVLLSFGIASFIGTSLSSFIL
                     KRSVKLALAGAPLILAVSALVLTLWGSDKIVATGVAIIWGLTFALVPVGWSTWITRSL
                     ADQAEKAGSIQVAVIQLANTCGAAIGGYALDNIGLTSPLMLSGTLMLLTALLVTAKVK
                     MK"
     gene            6059..6411
                     /locus_tag="IRB70_004500"
                     /pseudo
     CDS             6059..6411
                     /locus_tag="IRB70_004500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312624.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            6395..6718
                     /locus_tag="IRB70_004501"
     CDS             6395..6718
                     /locus_tag="IRB70_004501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HBC0634337.1"
                     /translation="MTAKTKFKSPAFEAIHSAAAGLSSVDAISAETMRTFDKACLTSV
                     QDLQPVEIKALREKLKVSQPVFAHYLNTSVSTVQKWESGAKRPNGISLKLLSIVQKHG
                     LEVLL"
     gene            complement(6834..7286)
                     /locus_tag="IRB70_004502"
     CDS             complement(6834..7286)
                     /locus_tag="IRB70_004502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418119.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1198 domain-containing protein"
                     /protein_id="HBC0634338.1"
                     /translation="MIWIMLATLAVVFVIGFRVLTSGARKAIRRLSDRLNIDVVPVES
                     MVDQMGKSAGDEFLRYLHRPDESHLQNAAQVLLIWQIVIVDGSEQNMLQWHRILQKAR
                     LAAPITDAQVRLALGFLRETEPEMQDINAFQMRYNAFFQPAEGVHWLH"
     gene            complement(7339..>7673)
                     /locus_tag="IRB70_004503"
     CDS             complement(7339..>7673)
                     /locus_tag="IRB70_004503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418120.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBC0634339.1"
                     /translation="VVVGVMFLLVMFFSPLVAMVPPYATAGALIFVGVLMTSSLARVN
                     WDDFTESVPAFITTVMMPFTFSITEGIALGFMSYCIMKVCTGRWRDLNLCVVVVAALF
                     ALKIILVD"
BASE COUNT         1855 a         2143 c         1883 g         1792 t
ORIGIN      
        1 gcattaccga acgcatcggt gaccttcacc cgcagcgtgt tcgccattgc accgtctgcc
       61 actgagtcgt ccttaatgac caccagatcc gcgatcttcg ccgtcctgac atcggcgata
      121 aatgtcacgt tctgactctg agtactgctg ttgatggttg cagtgactgc actgactccc
      181 gccgtctggc tggtgacact gatttccacc gtgccgtccg gctgcgtggt gaccaccgga
      241 gcaaccgttg cgccgttgcc tgccgtcacg ctgaccgtct gcccggcaag tgcattcccg
      301 aacgcatcgg tcaccctcgc ccgcagcgta ttcgccattg caccgtctgc cactgagtta
      361 tcccgggtga ccaccagatc agcgatcttc gccgtcctga catccgcgat aaacgtcacg
      421 tcccggctct gactgctgct gttgatactg acggtgaccg cactgctgcc cgccgtctgg
      481 ctggtgacac tgatttccac cgtgccgtcc ggctgcgtgg tgaccaccgg agcgaccgtt
      541 gcgccgttat ccgccaacac gctgaccgtc tgtccggcaa gtgcattccc gaacgcatcg
      601 gtgaccctca cttgcagcgt attcgccgtc gcgccgtctg ccaccgcgtt atcctggcta
      661 acgaccagat ccgcgatctg cgccgtgctg acatccgcaa taaacgtcac gttccggctc
      721 tggctgctgt tgttgatgct ggcggtgacc gcactggttc cggcggtctg gctggtgaca
      781 ctgatctcca ccgtgccatc cggctgcgtg gtgaccgtcg gagcagtcgt tgcgccgttg
      841 cctgccaaca cgctaaccgt ctgcccggca agtgcattcc cgaacgcatc ggtgaccctc
      901 gcccgcagcg tgttcgccgt cgcgccatct gccactgagc cgtcctgcgt caccaccagc
      961 tcagcgacct gcgccgtgct aacatcagca ataaagttca ccgttttact atcgctgctt
     1021 tgattgatct tcgcctcaac agtgctggca tccgctacgg tactgctcag atcaacctct
     1081 gccatgccat gcgcatccgt cctgatatct gcgctctgcc ctgcattggc aaatacagcc
     1141 gcccccttcg tcaccgtaaa ggtgacggtc tgctccggca gcacattgcc aaactgatct
     1201 tccacccgga cattcaccgt atgtcgatcg ctgccattcg ccagcacatc cgggttaccc
     1261 gttgtcactt gcatcgcgac aatttgtgcg ctggcggcat cgccactaat actgtaatca
     1321 tttgaagtca gagcgttcgc ccagccggac atctgtagct gtgcttttaa accggtgcca
     1381 gggagtaagg cggtatacgt tgcggtataa attccttttt gatcttcatt ccaggcgatg
     1441 ctttccgctt ttgtatttgg cagctggata gccaggttga tagcgtctcg ttgccccccg
     1501 accaggtttt catagctatc cttgagtgtt accgtaactt ttatcgcgcc gcccgcggtg
     1561 taggccgttt tgtcggtaac gatggaggaa taagccagca cagctccgct ttcgcggatg
     1621 gcatacgcat cggattgctg cgcgctactc catgtcgata gtttcagcgt ggcgtaatgg
     1681 cgatcgccag caatcttcgc ggttcgggtg gtggtgtaaa cgccatcaga ctcttcgctc
     1741 cagttacccg tttcattttt atctgtaccg ctcacctcga ccacactgct acccgccagc
     1801 agcgaagcca tccctttcac caggtttttc tgctcatcca taagggtaac tgacactttt
     1861 atcttgccac ccgcggtgta tgacacatcg tctgtcttaa tggtggaggt cagctgcgag
     1921 atatcgccag taataaaact cacttccaca gactgactac tgccattgat ctcggccttg
     1981 ataagactat ttaccgcctg gtcactggca aggttaacgc tggcaatccc gtctttatct
     2041 gtcgtcacaa taccgccatt tggatcggca aaaaccgccg caccattcac gaccgtgaag
     2101 gtaacatttt gtccctgcag taaattttga tgcacatccc tgaccgtcac agcgacggta
     2161 ttgtgatcgc gtctggcaac tgcgttattc gcggtgatct gcatcgctgc gattttggcg
     2221 gtatctttat cacccgcaat actgaacgca tccgaatgtt tggtttgcca gcccggcatc
     2281 gtcagctggg ccgttaattt gtcgccaatg agatgggccg tatagcttgc tttgtaaatt
     2341 ccctcacttt cttccgtcca ggcactaacg gcatcagcct tcgtgttgtc aactttaacg
     2401 gtttgtttga gaagttcttt tcgtccggta accccgttgc cgttatcatc tctcagggtc
     2461 actttaacga ctatcggctt acccgcgacg taattatcct ggtctgtctc aatcgtggag
     2521 tcagcgcggg atgccgtatt cgccacgata gcaatcagcg ctggcgtctt agcgatatcg
     2581 tcgccgttaa attgcggcat cagcgataac gcgccagacg tcttcccggc ggtaactatt
     2641 tgggtatagg ttccgttacc gttgtctttc cattcgctta aggcgaaatc ctgcaaacct
     2701 ttcacctgtg tttttaacgt catacctggg attggcttgc cgctggaatc tcgcgcggta
     2761 taggtcagcg ttgaggttga ttttccatca gcaagcagga tttgctgatc gacagaaagc
     2821 gttgaatcgg cgaggcttaa tgtgggtttt tccacgacca ccatactttc ttcacgccgg
     2881 gagaaatttc ctttcgaatc ttccgctgta accgctatcg ggtaagtgtt gtcggtttca
     2941 ggcattgccg tgaatcggta gggaggaata gtgacctgaa tatccttgcc ggaaacagct
     3001 acttttccgc ccgctgattg cagggaggcg gcttcaatgt cataaccttt cagcgcatat
     3061 ttggtttgca aggaagaaac cagcgattta acctcacccg gcttgccttt caacggatcg
     3121 gtcagcgtca gccgcaccag ctctttcttg cgatattcga ggacaatatt gttattacga
     3181 tcgaccaggt catagcgact gcccacaagg ctgcgtcgtg ctgcaacttc agccggatcg
     3241 agctgttttt gcagtgaatg gccgggttgc aacgtcaact ccataccaat tcgggtgtcg
     3301 ttttctccct gtttgccctg ccgttgctcg gcactaaagg agatcagggg aacgggggtg
     3361 taactcaaac ctgcggtaat cgcgtgagga tcattttgtc gctcgtcttt accaaacagc
     3421 gccacttcat cgccataata ttgttcatag accagcttgc cgcccagctg cggccaggcc
     3481 ggtaaccagc cttcggcgcg aagatcccac ccgttcgccg gacgtgcttc atagtcattg
     3541 tcgagttccg gtgcactacg ccagttactg aggcgcagat aaccgttgcc gctcagtttc
     3601 aggtaatcgc gccagtattc aacgcccatc ccggttcggg tgtgatagcg ggtcaggtca
     3661 tgatcgataa acatattgac gccagacatc cagctcgatg tgaaataacg ccagccgata
     3721 ccgtggttgg tttgagtgcg atcatccgta cggtgaagtg tgtgctggct gaagaccagg
     3781 ttatccggcg tttcgtacca gggatggaga aattcaaatg acgagctttt aaggctgaaa
     3841 tcttcatcca caccaagaga tacccgggca gttccccaac gactgagcca gtccgttgcc
     3901 tgcgcagagg cagaagaagc cacccagcca cgcgccatac tcgccgcctg ttcgctgtcc
     3961 atatcgcgtg ctaaaagtgt tccgctttgc tgcgccactt ccgcgacctg catttgcgga
     4021 tctttgccat cgcgctccat ctgcattgct ttcaggttgc gcgcttcagg gctgttactg
     4081 ttaatgaggg gcacatctat ttcatcgccc tgacgcacat tgtcaaagcc ccgcgcaaag
     4141 gtacggaact gattcaggcg acgtaattca tcaacggtga taccaaagcg tgccgcgacc
     4201 gttggtggcg attccaacgc acccagggta tatggaatag ttttaacgtt cggcaggatc
     4261 agtgacgcgg cagtatccga gtgcgcagga ttaatatgcg taggggcagc agccataaca
     4321 gggaatatag tttgtgttat caggcaaata ccggcggtca gacgacgtaa acgatccccc
     4381 aatccacata tggtgttatc gccccgacga tcgccattcc catgcgcttt ccctgccatt
     4441 tgtcatccct gtcgctatgc gttcagatta aatgaccttt ctttaacatg agggaaaatg
     4501 atgattcatg attagcaaat gatgaataca ggcggaataa tggaaataac aacaagataa
     4561 gaacaatacc tgatcaaggg ttatcagggg gaagaacagg agagctttcc cgccagagca
     4621 ataaccctcc tgtaaatacg ttacttcatt ttcacctttg cggtgaccaa taacgccgtc
     4681 agcaacatca atgtgccgga caacatcaac ggcgaagtca gaccaatatt atccagcgca
     4741 taaccgccga ttgccgcgcc acaggtatta gcaagctgaa taaccgccac ctgaatagac
     4801 ccggcttttt ctgcctgatc ggccagtgag cgggtgatcc acgttgacca gccgacagga
     4861 accaatgcaa aagttagccc ccagataatc gccacgccgg tagcaacgat tttatcgctt
     4921 ccccacaacg tcagcaccaa cgcactcaca gccagtatta acggcgcgcc tgctaaggcc
     4981 agttttaccg aacgtttaag aatgaacgac gaaagcgacg taccaataaa gctggcgata
     5041 ccaaaactca acagcaccag cgttaagcca tccacgccga atcccgccag gttcatatac
     5101 accgggcgaa tatacgtgaa gaaagcaaac tgcccggcga aagacatgaa gatggcgatc
     5161 atccctgcca tcacacccgg acgttgtaat aagcggaaag tattttgttt ctgatgcgag
     5221 ggttcgcctg gcagcgaagg caatgatttg ataatccaga aaatacacag cacgcccatc
     5281 accgccgccg cattaaagac attgcgccaa ccgataagct cgcctaaaaa actgcccaac
     5341 ggtgcggcaa tcaccagcgc aatagaaacc gcgccgaaga tcaccgacag cgccttcggc
     5401 accgtacgcg gcggtaccag acgcatggtc agcgacgccg acatcgccca gaacccaccc
     5461 agcgccagcc ccagacaggc acgaccgatt aaaagcaaac tgaatgagtt agcaaaggaa
     5521 accagcaagc aggagagcgt cagcaaaacg gcaaacaaaa taacaacata gcggcggtca
     5581 gtggcctgaa tggtctgggt aataaacaaa ctggcaaaca ttgccacaaa ggcggtcacg
     5641 gtcaccgatt gcccggcaac cccttccgaa atgcctaaat cctgggccat tggcgtcaac
     5701 aaactgacgg gcaaaaactc aacgataatc agacaggcga cgcaaaacgc caccgagaaa
     5761 acggctgacc agttcggtcg ggtgatggca tccgcgccgc ggttttcggc aataaattca
     5821 ctcatggtgt tacccgtggc atgtttcagg ggaaaagccg accactttaa cattgaaatg
     5881 tgtgacgcat ttaacgtttt tgcaactttt acggtgttgt gggaaaagtt cgaggctgct
     5941 cgaagaaata aaaatcatag ggcaaggtga tatgcatttt cgcaatgggg ttgggaataa
     6001 gggataaagt attgcacttg gtgatatact ttaataacag gatctcaacg atatacgcgt
     6061 gtttaaaacc aaatagtttg caagggaagc caggtctcat gcaatgacag atgaagagtt
     6121 gtgccgggcc attttagaaa cggaacaagg taaagctgat gtacttggtg gtggcgtttt
     6181 taaaaagcgc cttcaccgaa atcgtgagcg tgcaattatt ctggcaaaag ggggaagcaa
     6241 ttggttttac acgtttttat atgcaaaaca ggatatgtcg aacatcaata gtcaggaact
     6301 ggctgggttt cgtgaacttg caaagcatta tgccttcctg acgaaagccc aactaacagc
     6361 aatgattaca ctaaagaact gacagagatc tgctatgact gcaaaaacta aatttaaaag
     6421 tcctgcattt gaggctattc acagcgcagc ggctggattg tccagcgtcg atgctatttc
     6481 tgccgaaaca atgcgtactt ttgacaaagc ctgcctgacc agcgtgcaag acttacaacc
     6541 tgttgagata aaagcactgc gggaaaaatt aaaagtgagt caacccgtct tcgctcacta
     6601 tctcaatacc agcgtttcaa ctgtacaaaa atgggaaagt ggcgctaaac gccccaatgg
     6661 catttcatta aaactgctca gcattgtgca aaaacacggg ctggaggtgc tgctgtaaat
     6721 agaacgtaga taatgcgttc acctactgtc agttccaata ccggatgcgg cgtgaacgcc
     6781 taatccaccc tacaggtcag gcgcggtctg taggctgata agacgaagcg gttttaatgc
     6841 agccagtgaa cgccctcggc aggctgaaag aacgcgttat agcgcatctg aaaagcatta
     6901 atatcctgca tttcaggttc ggtttcgcgc agaaaaccca gcgccagcct gacctgagca
     6961 tcagtaatcg gcgcggcaag gcgggctttt tgtaaaatcc gatgccattg cagcatgttc
     7021 tgttcgctac catcgacaat gacaatttgc cagatgagca acacctgcgc ggcgttttgc
     7081 aggtgcgact catccgggcg atgcaaataa cgtaaaaatt cgtcaccggc tgactttccc
     7141 atttgatcga ccatcgactc cacgggtacg acatcgatgt tcagccgatc gctgagacgg
     7201 cgaatcgctt ttctggcccc ggatgtcagc acccgaaaac caatcacaaa cactaccgcc
     7261 agcgtggcga gcattatcca gatcatgagt tctcctgcgt aatcagaact cataatatct
     7321 ggaaaccctc gccagttact aatccaccag aataatcttc agtgcaaaca gagctgcgac
     7381 caccaccaca cacaggttca gatcgcgcca gcgcccggtg cacactttca tgatgcagta
     7441 cgacataaag ccgagtgcaa tcccttcggt gatcgagaaa gtaaagggca tcatcaccgt
     7501 ggtaataaat gcgggcaccg attcggtaaa atcatcccag ttaacgcgcg ccaggctcga
     7561 agtcatcagc acgccaacaa agattaacgc tccggcggtt gcgtaaggag gaaccatcgc
     7621 caccagcggt gagaagaaca taaccaacag gaacataacg ccgaccacaa ccg
//
LOCUS       DADXDL010000148         7477 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.148, whole genome shotgun sequence.
ACCESSION   DADXDL010000148 DADXDL010000000
VERSION     DADXDL010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7477)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7477)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7477
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.148"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            91..921
                     /locus_tag="IRB70_004504"
     CDS             91..921
                     /locus_tag="IRB70_004504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000843961.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBC0634340.1"
                     /translation="MKSVNVPRKSSNLLKRRLKIAEIVAAQGEIKVDDLSAQLGVSGV
                     TIRGDLSYLEQQGYLKRSFGGAIATPLSSEPEAIQPIAPLSLAQQMEIARHCARLIRD
                     RDTLFLGHGTICRKIIPLLSEVKKLRLITNDPEHALLANQFIDGEIILAGSEMLRPDT
                     ALAGKPLEQALQHFTITHSILEISHLDADGTLNINVPRLAAAWQLCFDNAQNKTVIVA
                     ADPAPSTAAIGHLHQAENVIVSRSINEQYQQQLQSADFVILYTSNECFTWSNRERLQE
                     "
     gene            953..1888
                     /locus_tag="IRB70_004505"
     CDS             953..1888
                     /locus_tag="IRB70_004505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBC0634341.1"
                     /translation="MGELLAEFLSRNPHQKFTQPGEFIGPFPSGAPAIFAAQVAKLSH
                     RAIFFGCVGNDDFGRLIIERLRHEGVITDGIHVMNNAVTGTAFVSYQNPQQRDFVFNI
                     PNSACGLFTAEHIDKDLLKQCNHLHIVGSSLFSFRMIDVMRKAITTIKSAGGTVSFDP
                     NIRKEMLSIPEMAQALDYLIEYTDIFIPSESELPFFARHKNLSEEQIVSDLLHGGVKH
                     VAIKRAQRGASYYKLKNGTLHAQHVAGHDIEIIDPTGAGDCFGATFITLFLSGFPAHK
                     ALQYANASGALAVMQQGPMEGISSLTDIEDFLQQH"
     gene            1981..2223
                     /locus_tag="IRB70_004506"
     CDS             1981..2223
                     /locus_tag="IRB70_004506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhdT family protein"
                     /protein_id="HBC0634342.1"
                     /translation="MDTRFVQAHKEARWALGLTLLYLAVWLVAAYLPGVTPGFTGFPR
                     WFEMACILTPLLFIGLCWAMVKFIYRDIPLEDDDAA"
     gene            2213..3664
                     /gene="panF"
                     /locus_tag="IRB70_004507"
     CDS             2213..3664
                     /gene="panF"
                     /locus_tag="IRB70_004507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312157.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium/pantothenate symporter"
                     /protein_id="HBC0634343.1"
                     /translation="MQLEVILPLVAYLVVVFGISVYAMRKRNTGTFLNEYFLGSRSMG
                     GIVLAMTLTATYISASSFIGGPGAAYKYGLGWVLLAMIQLPAVWLSLGILGKKFAILA
                     RRYNAVTLNDMLFARYQSRLLVWLASLSLLVAFVGAMTVQFIGGARLLETAAGIPYET
                     GLLIFGISIALYTAFGGFRASVLNDTMQGLVMLIGTVVLLIGVVHAAGGLSNAVETLQ
                     TIDPQLVTPQGADDILSPAFMTSFWVLVCFGVIGLPHTAVRCISYKDSKAVHRGIIIG
                     TIVVAILMFGMHLAGALGRAVIPDLTVPDLVIPTLMVKVLPPFAAGIFLAAPMAAIMS
                     TINAQLLQSSATIIKDLYLNIRPDQMQNETRLKRMSAVITLILGALLLLAAWKPPEMI
                     IWLNLLAFGGLEAVFLWPLVLGLYWERANAKGALSAMIVGGVLYAVLATLNIQYLGFH
                     PIVPSLLLSLLAFLVGNRFGTSVPQATVLTTDK"
     gene            3676..4557
                     /gene="prmA"
                     /locus_tag="IRB70_004508"
     CDS             3676..4557
                     /gene="prmA"
                     /locus_tag="IRB70_004508"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBC0634344.1"
                     /translation="MPWIQLKLNTTGANAEDLSDALMEAGAVSITFQDTHDTPVFEPL
                     PGETRLWGDTDVIGLFDAETDMKEVVAILENHPLLGAGFAHKIEQLEDKDWEREWMDN
                     FHPMRFGERLWICPSWRDVPDENAVNVMLDPGLAFGTGTHPTTSLCLQWLDSLDLTGK
                     TVIDFGCGSGILAIAALKLGAAKAIGIDIDPQAIQASRDNAERNGVSDRLELYLPKDQ
                     PEEMKADVVVANILAGPLRELAPLISVLPVSGGLLGLSGILASQAESVCEAYADSFAL
                     DPVVEKEEWCRITGRKN"
     gene            4886..5851
                     /gene="dusB"
                     /locus_tag="IRB70_004509"
     CDS             4886..5851
                     /gene="dusB"
                     /locus_tag="IRB70_004509"
                     /EC_number="1.3.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008785970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBC0634345.1"
                     /translation="MRIGQYQLRNRLIAAPMAGITDRPFRTLCYEMGAGLTVSEMMSS
                     NPQVWESDKSRLRMVHIDEPGIRTVQIAGSDPKEMADAARINVESGAQIIDINMGCPA
                     KKVNRKLAGSALLQYPDVVKSILTEVVNAVDVPVTLKIRTGWAPEHRNCEEIAQLAED
                     CGIQALTIHGRTRACLFNGEAEYDSIRAVKQKVSIPVIANGDITDPLKARAVLDYTGA
                     DALMIGRAAQGRPWIFREIQHYLDTGELLPPLPLAEVKRLLCAHVRELHDFYGPAKGY
                     RIARKHVSWYLQEHAPNDQFRRTFNAIEDASEQLEALEAYFENFA"
     gene            5877..6173
                     /gene="fis"
                     /locus_tag="IRB70_004510"
     CDS             5877..6173
                     /gene="fis"
                     /locus_tag="IRB70_004510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001465625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator Fis"
                     /protein_id="HBC0634346.1"
                     /translation="MFEQRVNSDVLTVSTVNSQDQVTQKPLRDSVKQALKNYFAQLNG
                     QDVNDLYELVLAEVEQPLLDMVMQYTRGNQTRAALMMGINRGTLRKKLKKYGMN"
     gene            6259..7143
                     /gene="yhdJ"
                     /locus_tag="IRB70_004511"
                     /pseudo
     CDS             6259..7143
                     /gene="yhdJ"
                     /locus_tag="IRB70_004511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417728.4"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="adenine-specific DNA-methyltransferase"
     gene            7227..7406
                     /locus_tag="IRB70_004512"
     CDS             7227..7406
                     /locus_tag="IRB70_004512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2556 family protein"
                     /protein_id="HBC0634347.1"
                     /translation="MIRKYWWLVVFAVFVFLFDTLLMQWIELLATETDKCRNMNSVNP
                     LKLVNCDELNFQDRM"
     gene            complement(7409..>7477)
                     /locus_tag="IRB70_004513"
     CDS             complement(7409..>7477)
                     /locus_tag="IRB70_004513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acrEF/envCD operon transcriptional regulator"
                     /protein_id="HBC0634348.1"
                     /translation="RMFMPDENITKLIRQTNELSVI"
BASE COUNT         1836 a         1810 c         1905 g         1926 t
ORIGIN      
        1 ccatgatttt cttttcgaat tgtcgatatt attgaagggt aactttcaaa gaaaaataca
       61 aggggctata gtgttacgca ttaaaggcca atgaagagtg ttaacgtgcc gagaaaatcg
      121 tctaacctac tgaaacgcag attaaaaatt gcagaaattg ttgccgccca gggtgaaatc
      181 aaagttgatg acttatctgc gcaacttggt gtctctggcg tgacgatccg cggcgatctc
      241 agttatctgg agcaacaggg atatttaaag cgatcatttg gcggtgctat tgcgacacca
      301 ctctcctctg aaccagaagc gatacaaccg atcgcgccat tgtctctggc acaacaaatg
      361 gaaatagcac gacattgcgc acggttaatt cgcgatcgtg acacgctatt tcttggacat
      421 gggacaatct gccgtaagat cattcccttg ctcagcgaag tgaaaaaact gcgtctgatc
      481 accaacgatc ccgaacatgc gctgctggca aatcagttta ttgatggcga aataatactg
      541 gctggcagtg aaatgctacg ccccgacacc gcactggccg gaaaacctct cgaacaggca
      601 cttcagcatt tcaccattac acatagcatt ctggaaatca gccacctgga tgctgatggt
      661 actttaaata tcaacgttcc cagacttgcc gctgcctggc aactctgttt cgataatgcc
      721 cagaataaga cggttatcgt tgccgccgat cctgcgccat caacggctgc tatcgggcat
      781 ttgcatcagg cagaaaatgt gatcgtcagc cgcagcatta acgaacaata tcagcaacaa
      841 ttgcagtcgg ctgatttcgt tatcctttat accagtaatg agtgctttac ctggtccaat
      901 cgcgaaaggc ttcaggaatg agaggggttt tgtgacaata actatctgcg ctatgggcga
      961 attgctggcc gagtttttgt cccgcaaccc acatcaaaaa ttcactcagc ctggggagtt
     1021 tatcgggcca tttcccagcg gtgcgccagc aatttttgct gctcaggtgg caaaactgtc
     1081 ccatcgggcc atcttctttg gatgtgttgg taatgatgat tttggccgac tcattataga
     1141 gcgtctccgt catgaaggtg tcattaccga tgggatccat gttatgaaca atgccgtcac
     1201 aggtacggcg ttcgtgagtt atcaaaatcc ccagcagcgg gatttcgtct ttaatatccc
     1261 taacagcgcc tgcggtttgt ttactgccga gcacattgat aaggatctgc ttaaacagtg
     1321 taaccatctg catattgtgg gctcatcgtt gttctcattt cgcatgatcg atgtcatgcg
     1381 taaagcaata acgacgatca aatcggctgg cggcaccgtt tctttcgatc ccaatattcg
     1441 caaagagatg ctgagcattc ccgaaatggc gcaggctctc gattatttga ttgaatatac
     1501 ggatattttt atccccagcg aaagcgaact ccctttcttc gcgcgtcaca aaaatctttc
     1561 agaagaacag attgttagcg atcttctcca cggcggcgta aaacatgtgg cgataaaacg
     1621 cgcccagcgt ggggccagct attacaagct taaaaacggt acattacacg cccagcatgt
     1681 tgcaggtcac gatatcgaaa ttatcgatcc aacgggtgca ggcgactgct ttggcgcaac
     1741 gtttatcact cttttcttat ccggtttccc ggcacacaag gcgctgcaat atgcaaatgc
     1801 cagcggcgcg ctcgccgtaa tgcagcaagg tccgatggaa gggatatcct cactgactga
     1861 cattgaagac tttttgcagc agcactgaac ggcaattttc tgtcagatta ttttccctgc
     1921 ctgaagagtt gccgtagaat tgcccgtttc tcgtatcccc ccatgaggag gaccccttcc
     1981 gtggacactc gttttgttca ggcccataaa gaggcgcgct gggcgctggg gctgaccctt
     2041 ttgtatctgg cggtatggtt agtagccgct tacttacctg gcgttacccc cggttttacc
     2101 ggctttccac gctggtttga gatggcttgc atcctgacgc cgctgctgtt tattggactg
     2161 tgctgggcga tggtgaaatt tatctatcgc gatatcccgc tggaggatga cgatgcagct
     2221 tgaagtgatt ctaccgctgg tcgcctatct ggtggtggtg ttcgggattt cagtttatgc
     2281 aatgcgtaaa cggaacaccg gcaccttcct caatgagtat ttcctcggca gccgttctat
     2341 gggcggtatt gtgctggcga tgacgctcac cgcgacctat atcagtgcca gttcgtttat
     2401 cggcgggcca ggagctgctt ataaatacgg cctgggttgg gtattgctgg cgatgattca
     2461 gcttcctgcg gtctggcttt cgctcggtat tctcggcaag aagttcgcga ttcttgcgcg
     2521 ccgctacaat gcggtgacgc tgaacgatat gctgtttgcc cgctatcaga gtcgtctgct
     2581 ggtgtggctg gcgagtttaa gtttgctggt tgcgttcgtt ggtgcgatga ccgtgcagtt
     2641 tatcggcggt gcgcgcctgc tggaaaccgc ggcgggtatt ccttatgaaa ccgggctgct
     2701 gattttcggt atcagcattg cgttgtatac cgcctttggt ggctttcgcg ccagcgtgct
     2761 gaacgacacc atgcaaggac tggtgatgct gattggcacc gttgtgctgc ttattggcgt
     2821 ggtccatgct gctggcggct taagcaatgc agtagagacg ctgcaaacca ttgatccgca
     2881 actggttacg ccacaaggcg ctgacgatat tctgtcacct gcgtttatga cgtcgttctg
     2941 ggtgctggtg tgctttggcg ttattggcct gccgcatact gcggtgcgct gtatctccta
     3001 taaagacagc aaagcagtac atcgggggat catcatcggt acgattgtag tcgcaatcct
     3061 gatgttcggt atgcacctag ccggagcatt aggtcgtgca gtgatccccg atctcaccgt
     3121 accggacctg gtgatcccga cgttgatggt aaaagtactg ccaccgtttg ctgccgggat
     3181 cttccttgca gctcctatgg ctgcgatcat gtcgacgatc aacgcccaat tgctgcaaag
     3241 ttccgctacg atcattaaag atctctatct gaatatccgt ccggatcaaa tgcaaaacga
     3301 gacgcgcctg aagcggatgt cggcggtgat tacgttgatt ctcggcgcgt tgctgctgct
     3361 tgctgcatgg aagccgcctg aaatgatcat ctggctgaat ttgctggcct tcggcgggct
     3421 ggaagctgtc ttcctgtggc cgctggtact gggtctttac tgggaacgcg ctaacgccaa
     3481 aggcgcgcta agtgcgatga tcgttggcgg cgtgctgtat gccgtacttg cgacactgaa
     3541 tattcagtac ctgggcttcc accctatcgt gccctcgttg ctgctaagtt tgctggcttt
     3601 cctggtcgga aaccgtttcg gtacgtccgt cccgcaagct accgttttga ctactgataa
     3661 ataaagagtt ttgccatgcc ttggatccaa ctgaaactga acaccaccgg cgcgaacgcc
     3721 gaagatctta gcgatgcgct gatggaagcg ggtgccgttt ctatcacttt tcaggatacc
     3781 cacgatacgc ctgtatttga gccgcttccg ggcgaaacgc gtctgtgggg cgacaccgat
     3841 gtgattggcc tgttcgatgc tgaaaccgac atgaaagaag tcgtggcgat tctggagaat
     3901 catccgctgc tcggcgcagg cttcgcgcac aaaatcgaac aactggaaga taaagactgg
     3961 gagcgcgaat ggatggataa tttccaccca atgcgctttg gcgaacgtct gtggatctgc
     4021 ccaagctggc gtgatgtgcc ggacgaaaac gccgtcaacg taatgttaga cccaggtctg
     4081 gcgtttggta cagggactca tccaactacc tctctgtgcc tgcaatggct cgacagcctc
     4141 gatttaaccg gtaaaacggt catcgacttt ggctgtggtt ccggcattct ggctatcgcg
     4201 gcgctgaaac tgggtgcagc aaaagccatt ggtattgata ttgatccgca ggcgattcag
     4261 gccagccgcg acaacgccga acgtaatggc gtttctgacc gtctggaact ctacctacct
     4321 aaagatcagc cagaagaaat gaaagccgac gtggtggtcg ctaacatcct tgcaggccca
     4381 ttacgtgaac tggcaccgtt aatcagcgtc ctgccggttt caggtggctt gctgggcctt
     4441 tccggtattc tggcaagcca ggcagagagc gtttgtgaag cttatgccga cagcttcgct
     4501 ctggacccgg tcgtggaaaa agaagagtgg tgccgcatta ccggtcgtaa gaattaacct
     4561 tcgcatcgcc gtagggtgac gcaaggcgaa gtgcgagcaa ggtcacaaaa ggcacgttaa
     4621 tttgccgatt atttacgcaa atttgcgtgc caaaattttc attcataaag aaaaattgag
     4681 aacttactca aatttcttgg agtgtaaatt ttagtcacta ttttctaata taatgatttt
     4741 tatgagtaat tatcgcgcca agctcatttt aaatgcaatt ctttgatcca tctcagatga
     4801 ttggtcaaag tttggccttt catctcgtgc aaaaaatgcg taatatacgc cgccttgcag
     4861 tcacagtatg gtcatttctt aactcatgcg catcggacaa tatcagctca gaaatcgcct
     4921 gatcgcagcg cccatggctg gcattacaga cagacctttt cggacgttgt gctacgagat
     4981 gggagccgga ttgacagtat ccgagatgat gtcttctaac ccacaggttt gggaaagcga
     5041 caaatctcgt ttacggatgg tgcacattga tgaacccggt attcgcaccg tgcaaattgc
     5101 tggtagcgat ccgaaagaaa tggcagatgc agcacgtatt aacgtggaaa gcggtgccca
     5161 gattattgat atcaatatgg gttgcccggc taaaaaagtg aatcgcaagc tcgcaggttc
     5221 agcccttttg cagtacccgg atgtcgttaa atcgatccta accgaggtcg tcaatgcagt
     5281 ggacgttcct gttaccctga agattcgcac tggctgggca ccggaacacc gtaactgcga
     5341 agagattgcc caactggctg aagactgtgg cattcaggct ctgaccattc atggccgtac
     5401 acgcgcctgt ttgttcaatg gagaagctga gtacgacagt attcgggcag ttaagcagaa
     5461 agtttccatt ccggttatcg cgaatggcga cattactgac ccgcttaaag ccagagctgt
     5521 gctcgactat acaggggcgg atgccctgat gataggccgc gcagctcagg gaagaccctg
     5581 gatctttcgg gaaatccagc attatctgga cactggggag ttgctgcccc cgctgccttt
     5641 ggcagaggtt aagcgcttgc tttgcgcgca cgttcgggaa ctgcatgact tttatggtcc
     5701 ggcaaaaggg taccgaattg cacgtaaaca cgtttcctgg tatctccagg aacacgctcc
     5761 aaatgaccag tttcggcgca cattcaacgc cattgaggat gccagcgaac agctggaggc
     5821 gttggaggca tacttcgaaa attttgcgta aacagaaata aagagctgac agaactatgt
     5881 tcgaacaacg cgtaaattct gacgtactga ccgtttctac cgttaactct caggatcagg
     5941 taacccaaaa acccctgcgt gactcggtta aacaggcact gaagaactat tttgctcaac
     6001 tgaacggtca ggatgtgaat gacctctatg agctggtact ggctgaagta gaacagcccc
     6061 tgttggacat ggtgatgcaa tacacccgtg gtaaccagac ccgtgctgcg ctgatgatgg
     6121 gcatcaaccg tggtacgctg cgtaaaaaat tgaaaaaata cggcatgaac taattcaggt
     6181 tagctaaatg cttgattaaa aaggcgctac tcggcatggg gaagcgcctt ttttataggt
     6241 gtcacaaagg gagtgaccat gagaacagga tgtgaaccga cccgatttgg taatgaagca
     6301 aagaccatca tccagggtga tgcattaacc gaacttaaaa agatccccgc cgatagtgta
     6361 gatctgatct ttgccgaccc accgtataac atcggtaaaa attttgatgg tctgatcgaa
     6421 gcctggaaag aagatctgtt tatcgactgg ctgtttgaag tgattgcata gtgccaccgc
     6481 gttctgaaaa agcagggcag catgtacatc atgaacagca cggaaaacat gccctttatc
     6541 gatctccagt gccgcaagct ttttaccatc aaaagtcgca tcgtctggtc atatgacagt
     6601 tctggagtgc aggcgaaaaa acactacggc tccatgtacg aacccatcct gatgatggtg
     6661 aaagacgcaa agaactacac gttcaacggt gatgctattc tggtagaagc caaaaccgga
     6721 tcgcagcgcg cgttgatcga ttatcgcaaa aatcctccac agccttacaa tcatcaaaaa
     6781 gtaccgggta acgtctggga ttttccgcgc gtgcgttatt tgatggatga atatgaaaac
     6841 cacccgacgc aaaaaccgga agccttactg aaacgcatta ttctcgcctc ttccaaccca
     6901 ggcgatatcg ttctcgaccc gtttgccggt agctttacta ccggtgccgt agccgtcgcc
     6961 agcgggcgaa aattcattgg tattgagatc aacagcgagt acatcaaaat ggggcttcga
     7021 cggctggatg tcgcgtcgca ttactctgcg gaagaactgg cgaaagtgaa aaaaagaaag
     7081 accggcaacc tgtcaaaacg aagccggtta agcgaagttg accccgatct cattgcaaag
     7141 taaaggaagt gtaagcctgg ttttcagatt attcatttcg tgtatatttc ctgccagact
     7201 tggttaaaca tgcacaggct caggtaatga ttcgcaagta ttggtggctc gtcgttttcg
     7261 ctgtcttcgt ttttctgttt gatactttac tgatgcagtg gattgaactg ctggcaacag
     7321 aaacagacaa atgccgcaat atgaactcag ttaatccact aaaactggtt aactgtgacg
     7381 aactgaattt tcaggacaga atgtgaattt atatgacact taattcattc gtttgacgaa
     7441 ttaatttcgt tatgttttca tctggcataa acattct
//
LOCUS       DADXDL010000149         7373 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.149, whole genome shotgun sequence.
ACCESSION   DADXDL010000149 DADXDL010000000
VERSION     DADXDL010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7373)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7373)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7373
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.149"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..552
                     /locus_tag="IRB70_004514"
     CDS             <1..552
                     /locus_tag="IRB70_004514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016235876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBC0634349.1"
                     /translation="PAFPSGNAWTDTVALTVVISGVVSRLVFGKTGLFGKPEQGIRHC
                     YPPQDKCWIPYHSRIPQLSVLGLGIGLMAGFLGLKFGGNGALLAFGISAFSLIFLHFN
                     TQVPVSHHISLPAALVAVPSGSLIWAAIVGIICAILGELMSRIFLIHGDTHIDPPAMV
                     ITIMTTMINLLATIGLFTLVPLF"
     gene            1164..1533
                     /locus_tag="IRB70_004515"
                     /pseudo
     CDS             1164..1533
                     /locus_tag="IRB70_004515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001352292.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="reverse transcriptase/maturase"
     gene            1533..2126
                     /locus_tag="IRB70_004516"
                     /pseudo
     CDS             1533..2126
                     /locus_tag="IRB70_004516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001381615.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="maturase"
     gene            2709..3938
                     /locus_tag="IRB70_004517"
     CDS             2709..3938
                     /locus_tag="IRB70_004517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001584619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PocR ligand-binding domain-containing protein"
                     /protein_id="HBC0634350.1"
                     /translation="MKNKYKLNEFLDVKRLQTLQDNFSKSMMIALVVVDENGIPVTKP
                     SGFSDFCMRSRLNPTLAHHCYESDNAGGRAAMHARKPVVYRCHCGFVEFAVPIMINDH
                     YLGAFISGQVKVEEEKEQSISYILNNNDVWKDNPWLINLHQNTRRMPYERFESTASTL
                     LHVSSYLVEQAHTNNIQRELRKKDLALANELRKRVEIERSLHEAEFKALSYQINPHFL
                     FNVLNTIGRLAFLEDAQRTETMVHDFSDMMRYLLRKNSHGLITLRNEINYVNNYMSIQ
                     KVRMRDRFDYLCDIPEKYLDVVCPFLILQPLVENFFNYVVEPRDSNSHLLIRATDDGL
                     NVIIEVTDNGDGIAPDTINRILSGDQKLQKGSIGINNIKNRLKLLFGESYGLEIMSPN
                     KPRMGTTIKLRFPMQEA"
     gene            3955..5010
                     /locus_tag="IRB70_004518"
     CDS             3955..5010
                     /locus_tag="IRB70_004518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000494232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBC0634351.1"
                     /translation="MFTIVIVEDEPIELESLRQIISQCVENAAIHEASTGKKAIHLID
                     QLSQIDMILVDINIPLPNGKQVIEYLKKKNSDTKIIVITANDDFDIVRSMYNLKVDDY
                     LLKPVKKCILTDTIKKTLAFDEGENEKSRALKQKVFAMIDDCDYTQWHNFIFDTLNGA
                     CPVDMIEEDKRKDVIDFLEIVSQYMTAKGEKLMPTNRKVAALIKDINQYGMMESRYFR
                     IMISLLTISEELFDYALKGYTGNIDFIERAKFHIEKNILRNLTLDDVAAKSFVSACYL
                     SRTFKKITGFGFSNYIATRKITIAKSLLRFSDLQVNTIALELAYQDSNYFCRIFKKDT
                     GMTPSDYRKVVSPGITR"
     gene            5139..6290
                     /locus_tag="IRB70_004519"
     CDS             5139..6290
                     /locus_tag="IRB70_004519"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBC0634352.1"
                     /translation="MNDYLFTSESVAEGHPDKMADQISDAILDAILLQDPWGKVACEC
                     LVKTGATIVAGEISTHAAVDIEKIVRNTIKEIGYDHSRLGFDGNTCCVLNILGKQSAN
                     IADGIRGHSMEELGAGDQGITFGYACDETSELMPATLVYAHRLMERQAQLRKSQRLPF
                     LLPDAKSQVTLRYQDNRVHSVDTVVVSTQHSPDVSLDALREAVIEEIVKPVMPSHWLT
                     PQTRFLVNPAGSFVIGGPVGDCGLTGRKIIVDTYGGAACHGGGAFSGKDPSKVDRSAA
                     YAARYVAKNIVAAGLASRCEVQLGWAIGLPRPVSVRINTFGTQTVSSEALLRGVNSHF
                     DLSVFGIITTLDLLVPRYRKTACYGHFGRDSFPWEVTDKAALLYEDVGR"
     gene            6335..6880
                     /locus_tag="IRB70_004520"
     CDS             6335..6880
                     /locus_tag="IRB70_004520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001564047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMC domain-containing protein"
                     /protein_id="HBC0634353.1"
                     /translation="MSGKSLGLIETVGMSAAVEAADAAMKSANVSLVGYELTKGGGMV
                     TVKLEGEVGAINAAVAAAISAASRVGEVYAHKVIARTAQHIEQIIHSKVTAGVAEPQP
                     EVPAAQPTLQAENAPSQTFPVVNLDTSISASCMDVTDETLKSMEQHQPVKPSIENTKP
                     TKSDVPQEAAKKGPRSSGKKK"
BASE COUNT         1982 a         1710 c         1927 g         1754 t
ORIGIN      
        1 ccggccttcc cgtccggcaa tgcttggacc gataccgtgg cactaaccgt ggtgatttct
       61 ggcgtggtct cgcgtctggt tttcggtaaa actggcctgt ttggaaaacc ggagcaggga
      121 attcgtcact gctatccgcc gcaggataag tgctggatac cttaccatag ccgcattccg
      181 cagctttccg tgctgggctt gggtattggc ttgatggcag gctttttagg cctgaagttt
      241 ggcggcaacg gcgcgctgct ggcgtttggt atttccgcgt tctcactgat tttcctgcat
      301 ttcaatactc aggtaccggt gtcacatcat atttcgctgc ctgccgcgtt ggtagcggtg
      361 ccatcaggta gcctgatttg ggctgctatc gttggcataa tttgcgcgat attgggtgaa
      421 ctgatgtcgc gtatcttcct gatccacggc gatacacata ttgacccgcc ggcgatggtc
      481 atcaccatta tgaccacgat gattaatctg ttggcgacca ttggattatt taccttggtt
      541 cccctgtttt aatcccgcca taacaaaaag ccagcagtgt ctgcctgctg gctttttgtt
      601 atgtgcgccg tgactggcgc tgttcttcaa ctgtggtggc agaagaacga ctaagaggtg
      661 aaagtcctcc acacacccgg tgaggggaag tgttagcgga aggcaagggt gttcatcgcg
      721 aggtgaaatc tgaaggaagc tggatgcaaa atgctggcct gacgaacagg aagcggttaa
      781 ggcggcgcag cagggtaagg tggcacaaat caccaaagcc cgatactcac acggaacgct
      841 gtgacgtaaa gccgacaggc ataagcagga aagtcgcgtg aattaccccg ggagatctgt
      901 cgccctgcca gtgtgctacc ggcgccgtga ggcgccggga tggggcggca gaagtcagcc
      961 gacgccgtag tagtgctgca aaaccggcag catgaagggc cgaacatgat taactgtgat
     1021 taggacatcc gaacccgatg atgattaatg aagcacaagc gcaggcaact gcgaccagcg
     1081 gcagaggaga cggacagtat ccgtcagggc tgcatgatgg cgctgaaatc agcacggcgg
     1141 cgggtgggca aacgaaagcg gaagtgccgc tgacgatgga agcggtgata acgagagaaa
     1201 acctgatgct ggcttatcag cgcgtggtgg aaaacaaagg cacggcgggg gtggataacc
     1261 tcagcgtggc ggagttgaaa ccgtggctga agaagaactg gcgcagcgtc aggcaggcat
     1321 tgattgacgg aaactaccag ccgcgggcaa tacgccggat ggatatcccg aagccgcatg
     1381 gcggcgtgag aacctcaggc atcccgacgg tggtggacag gcttatccag caggcggtgc
     1441 aacaggcaca gcgttacata cggggtggca aacggtgggt ggtggatatg gatctggaga
     1501 agttcttcga ccgggtggat cacagactcc tgatgacgcg tctggccaga acgataaagg
     1561 acaggcgggt gctgtgactg atacgccgct acctgaaagc ggaaatggtt aaagacgggc
     1621 aaagggagaa acggcaggcg ggcatgctgc agggcggccc actgtcgccg ttactgtcga
     1681 acatcctgct ggatgaactg gataaagaac tggagcgtcg tggacacagc ttctgccgct
     1741 acgcagacga ctgcaacatc tacgtaagca gccggaaagc gggcgaccat ctgctgaaga
     1801 acatcagggc gttcgtggag aacaaactga aggtgaatga gaagaagagc gcggtggcgc
     1861 gcccgtggga tcggaagttc ctcgggtaca gtgtgacatg gcacaaacag gcgaagctga
     1921 agatagccct gacgagcgtg aacaggctga aggagaaagt ccacagtctg acgacgggaa
     1981 accggagcaa atcagtgaaa gcgacaatca atgctctgac actagtgctg tgtggatgga
     2041 taagctactt caggctgacg gaagtcagag gagtgctgga ggagctggat ggctggatca
     2101 aacggaaact gcgttgcttg ttgtagcggc agtggaagag accgctaacc cgggcaaaga
     2161 acctgcaaag agcaggactg agtaaggaca gggcaatgat ctctgcgtac aacaaccacg
     2221 ggccatggtg gaactcaggg tcaagccata tgaatcaggc gataaagaat acatggttca
     2281 ggaggcaggg tctgatatca ctgctggaac agtagaggca gttccagagt taacatgaac
     2341 cgccgtatgc ggaaccgcac gtacggtggt gtgagaggac ggcgggagtg atcccgcctc
     2401 ctactcgatc aattttaaaa cacctcctat gtaggtggtg atcgttcatg tggggctttc
     2461 tgacagactg cctcgtcatt ccattcgtat cgccagtaac tggcgtttgt attgtggcag
     2521 ttctggtata cgtttccctg tgtatctgca ctggttcagc aaggtttgaa aaggagtatc
     2581 ccttgcaaat aaccgaagca ttactttcag agccggagct gtttttgttg ctgtgatcca
     2641 tttcaatttt ttcgtgacaa attatttata aatatatgat tatgttttta aaaatgcagg
     2701 ctgaaagtat gaagaataaa tacaaattaa atgagttttt ggatgtaaaa cgccttcaga
     2761 ccctgcagga caacttttca aaatcaatga tgatcgcgct cgtggttgtg gatgagaatg
     2821 gtatcccggt cactaagccc agcggttttt cagacttctg catgcgttcg cgtctcaacc
     2881 cgacactggc gcaccactgt tatgaaagcg acaacgctgg tggccgggcc gcgatgcacg
     2941 ctcgcaaacc ggtggtttat cgctgccact gcggttttgt cgaattcgct gtcccaatca
     3001 tgattaacga tcattatctc ggtgctttta tttccggtca ggtaaaagtc gaagaagaga
     3061 aagaacagag catttcctat attctgaata ataatgacgt ctggaaagat aatccttggt
     3121 taattaattt gcaccagaat acacgtcgca tgccgtatga gcgttttgag tctactgcct
     3181 cgacgttact acacgtatcg tcttatctgg tcgaacaagc gcacaccaat aatatccaac
     3241 gcgaacttcg taaaaaggat cttgcactgg ctaatgagtt aagaaaacgt gtagagatag
     3301 aacgctcact acatgaagct gaatttaaag cgctctctta tcagataaat ccgcactttt
     3361 tatttaacgt attaaatacc attggccggt tagcttttct tgaagatgcg cagcgtaccg
     3421 aaacaatggt gcacgatttc tctgacatga tgcgctattt gttacgtaaa aatagtcacg
     3481 gcctgattac tctgcgtaat gaaataaatt acgtcaacaa ctatatgtcg atccaaaaag
     3541 tgcgtatgag agaccgtttc gattacctgt gcgatatccc ggaaaaatat ctggatgtag
     3601 tctgcccgtt tttgatcctg caaccgctgg tggaaaactt ctttaactac gtagtggagc
     3661 caagggatag caatagtcat ctgctgatcc gtgccacgga cgatggcctg aacgtgatta
     3721 ttgaagtcac tgacaatggc gacggcatcg caccagatac cattaatcgc attttatcag
     3781 gcgaccaaaa attgcaaaaa ggcagtattg gcattaacaa cataaaaaat agattgaagt
     3841 tgttatttgg cgagagctat ggcttggaaa taatgagccc taacaaaccc aggatgggta
     3901 caaccattaa acttcggttc ccaatgcagg aagcctgata caggaaaagg acatatgttt
     3961 accattgtta tcgttgaaga tgagcccatc gaattagaat ccctgcggca gattatctcc
     4021 cagtgtgtgg aaaacgctgc gatccatgaa gcctcaaccg gtaaaaaagc gattcactta
     4081 attgaccaac tgagtcaaat cgatatgatc ttagtggaca ttaatattcc gttgccgaac
     4141 ggtaaacagg tgattgaata tctgaagaaa aaaaacagcg atactaaaat catcgtaatc
     4201 acggccaatg atgactttga tatagtacgc agcatgtaca accttaaagt ggatgattat
     4261 ctgctcaaac cagtgaaaaa atgtatcttg accgacacca tcaaaaaaac cctagcattc
     4321 gacgaaggag aaaatgaaaa atcccgcgcc ctaaaacaga aagtgttcgc catgatagac
     4381 gattgcgatt acacccagtg gcacaacttt atttttgaca cgctcaacgg tgcctgtccg
     4441 gtggatatga tagaagagga taagcgcaaa gacgtgatcg attttctgga aatagttagc
     4501 cagtatatga ccgccaaagg ggaaaagtta atgccgacta accgtaaagt cgccgcgctg
     4561 atcaaagaca tcaaccagta tggcatgatg gaaagccgct atttccgcat catgatcagc
     4621 ctgctgacca ttagcgaaga gctgtttgat tacgcattaa aaggctatac aggcaatatc
     4681 gattttatcg aacgagcgaa attccatatt gagaaaaata ttctcagaaa cttgacgctc
     4741 gatgacgtgg cagcaaaatc gtttgtcagt gcctgctatt tgagccgtac ctttaagaaa
     4801 attaccgggt tcgggttttc gaactatatt gccacgcgta aaattactat cgccaaatcg
     4861 ttattgcggt tcagtgactt acaagtaaat accattgcgc tggaactggc ataccaggat
     4921 tcaaactatt tttgccgcat cttcaaaaaa gatactggca tgaccccctc tgattatcga
     4981 aaagtcgtgt ccccgggaat tacacggtga tggcgtgatt ttgcattggc ccgataatga
     5041 aagcaaaata gtccaacacg cccgcaagat agtttacgcc cacttgtcag gttcctatcc
     5101 taagatagga ataaacttcc caaacaagtg ggctcgcttt gaacgattac ctgtttacct
     5161 ccgaatccgt tgccgaaggg catcccgata aaatggcgga ccaaatttct gatgccattt
     5221 tggatgcgat actcctacag gacccgtggg gtaaggttgc ctgtgaatgc ttggtgaaaa
     5281 ctggtgccac tattgttgcc ggagaaatat ctacccatgc cgccgtggat attgagaaga
     5341 ttgtccgcaa caccataaaa gagattggtt acgaccattc gcgattgggg tttgatggca
     5401 atacctgctg tgtattaaat atccttggca aacagtccgc caatattgct gacggcattc
     5461 gcggccactc gatggaagaa ctgggggcgg gcgatcaggg catcaccttc ggttacgcct
     5521 gtgatgaaac gtcggaactg atgcccgcca cgctggtata cgcccatcgt ctgatggagc
     5581 gccaggcgca gttgcgtaaa tcccaacggt taccattttt actccctgat gccaaaagcc
     5641 aggttaccct gcgctatcag gataatcgtg ttcattcagt agataccgtt gtggtgtcta
     5701 cccaacacag ccctgacgtt tctctggacg cgctacggga agcggtcatc gaagaaattg
     5761 ttaaacctgt gatgccttcg cactggctca cgccacaaac ccgctttctg gtgaaccctg
     5821 caggcagttt tgtgattggc gggccggtgg gtgactgcgg gctaacgggg cgtaaaatta
     5881 ttgttgatac ctatggcggc gcggcttgcc atggcggcgg cgcgttttca ggcaaagatc
     5941 cgtcgaaagt cgatcgttcc gccgcctacg ctgctcgcta tgtggcgaaa aacatcgtcg
     6001 ccgctgggct tgcctcacgc tgtgaagtcc agttgggatg ggccatcggc ctgccccgcc
     6061 ctgtttccgt caggattaac accttcggta cacaaacagt gtcatctgaa gcgttgctga
     6121 gaggcgttaa cagccatttc gatcttagcg tgttcggcat cattactacg cttgatctgc
     6181 tggtcccccg ctatcgtaaa acagcctgct atggtcactt tggtcgcgac agctttccgt
     6241 gggaagttac ggacaaagcg gcgctattat acgaagacgt tggacgttaa gccgacgacg
     6301 cgcagcacag ttgaatttat tacaggagaa atttatgtct gggaaaagtt taggcttaat
     6361 cgaaaccgtc gggatgtctg cggcggtaga agccgccgat gccgcaatga aatccgctaa
     6421 cgttagtctg gtaggctatg aattgacgaa aggcggcggg atggtgaccg tgaagctgga
     6481 aggggaagtg ggcgcaatta acgcggcggt agcggcagcc atcagcgcgg caagccgggt
     6541 tggcgaggtg tatgcccata aggtgatcgc ccgcaccgcg cagcatatcg agcagattat
     6601 tcactctaaa gtgaccgccg gcgtcgcaga acctcaacct gaagtgcctg ctgcacaacc
     6661 gacactgcag gctgaaaacg cgccttcaca gacattcccg gtggttaacc ttgatacgtc
     6721 aatcagcgca tcctgtatgg atgtcactga tgaaacgctg aagtccatgg agcagcatca
     6781 accggttaaa ccctcaatag aaaacactaa acctacaaaa tctgatgtac cgcaggaggc
     6841 agcaaagaaa ggtcctcgtt ccagcggcaa gaaaaaataa gtaaattgct atgacgctgc
     6901 cgcgataaca atttctttat cgcggcattt ttttgcttaa cagataaagt aaaaaaccat
     6961 ctgcatagcg ggcggctttg acacggcccc ctgaaagggg gcttaaacac taccctttca
     7021 ggcccagttg tatttgtctt tcttcttcct cttttgctac cttgttcgaa aagggacgct
     7081 cgtcctcgcc cactgttctg tatgcatacc tgctcccact gcaaattata ttgctgggct
     7141 atgttaacaa gcctatatgc tattaaaaac tcatgagcaa catattgata ataccattct
     7201 tatatatcca cgcttaagta aataacgctt acataactaa ctattccatc tcacttcttc
     7261 cttagcgagt tttcggtatg caataggagc tataccaaag cggcgagtaa atgcccttgt
     7321 aaatgtctgc tgaaaatcaa actgatattt aaaagtgata gtcgtgaccg att
//
LOCUS       DADXDL010000150         7341 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.150, whole genome shotgun sequence.
ACCESSION   DADXDL010000150 DADXDL010000000
VERSION     DADXDL010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7341)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7341)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7341
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.150"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            172..1539
                     /locus_tag="IRB70_004521"
     CDS             172..1539
                     /locus_tag="IRB70_004521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001526835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GGDEF domain-containing protein"
                     /protein_id="HBC0634354.1"
                     /translation="MEKDYLGISSTVLVSLLFGLALVLVNSWFNQPTVEEVVPRSTYL
                     MVMIALFFIDTVAFIFMQLYFIYDRRQFSNCILSLAFLSCLIYFIKTVIIIQQIIEGR
                     LTSSVVQNDIAIYYLFRQMSLCVLIFLALVNKVSENTKQRNLFSKKVTLCITLFFVLG
                     GPIVAHIFSSHYESYDLHIAELTNENGQVVWKASYVTIMIFMWLTLLSVNLYFNGLRC
                     DIWNGVSVIAFCAVLYNISLLFMSRYSVSIWYISRTIEVVSKLTVLVIFMCHIFSALR
                     VTKDIAHRDPLTNIFNRNYFFNELTVQSASAKKTPYCVMIMDIDHFKKVNDTWGHPVG
                     DQVIKTVVNIIGKSIRPDDLLARVGGEEFGVLLTEIDTECAKALAERIRENVERLTGD
                     NPEYAIPQKVTISIGAVVTQKNELNPKEIYQLADNALYEAKETGRNKVVVKEAEILIN
                     RKDDE"
     gene            complement(1644..1731)
                     /locus_tag="IRB70_004522"
     tRNA            complement(1644..1731)
                     /locus_tag="IRB70_004522"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1695..1697),aa:Ser,seq:gga)
     gene            1965..2903
                     /gene="ghrA"
                     /locus_tag="IRB70_004523"
     CDS             1965..2903
                     /gene="ghrA"
                     /locus_tag="IRB70_004523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415551.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxylate/hydroxypyruvate reductase GhrA"
                     /protein_id="HBC0634355.1"
                     /translation="MDIIFYHPTFDTQWWIEALRKAIPQARVRAWKSGDNDSADYALV
                     WHPPVEMLAGRDLKAVFALGAGVDSILSKLQAHPEMLKPSVPLFRLEDTGMGEQMQEY
                     AVSQVLHWFRRFDDYRLQQNSSHWQPLPEYHREDFTIGILGAGVLGSKVAQSLQTWCF
                     PLRCWSRTRKSWPGVQSFAGREELSAFLSQCRVLINLLPNTPETVGIINQQLLEKLPD
                     GAYLLNLARGVHVVEDDLLAALDSGKVKGAMLDVFNREPLPPESPLWQHPRVTITPHV
                     AAITRPAEAVDYISRTIAQLEKGERVCGQVDRARGY"
     gene            2958..3695
                     /gene="ycdX"
                     /locus_tag="IRB70_004524"
     CDS             2958..3695
                     /gene="ycdX"
                     /locus_tag="IRB70_004524"
                     /EC_number="3.1.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding phosphatase"
                     /protein_id="HBC0634356.1"
                     /translation="MYPVDLHMHTVASTHAYSTLSDYIAQAKQKGIKLFAITDHGPDM
                     EDAPHHWHFINMRIWPRVVDGVGILRGIEANIKNVDGEIDCSGKMFDSLDLIIAGFHE
                     PVFAPHDKATNTQAMIATIASGNVHIISHPGNPKYEIDVKAVAEAAAKHQVALEINNS
                     SFLHSRKGSEDNCRAVAAAVRDAGGWVALGSDSHTAFTMGEFEECLKILDAVDFPPER
                     ILNVSPRRLLNFLESRGMAPIAEFADL"
     gene            3719..4273
                     /gene="ycdY"
                     /locus_tag="IRB70_004525"
     CDS             3719..4273
                     /gene="ycdY"
                     /locus_tag="IRB70_004525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone YcdY"
                     /protein_id="HBC0634357.1"
                     /translation="MNEFSILCRVLGSLYYRQPQDPLLVPLFTLIREGKLAANWPLEQ
                     DELLTRLQKSCDMTQVSADYNALFIGDECAVPPYRSAWVEGATEAEVRAFLSERGMPL
                     ADTPADHIGTLLLAASWLEDQSTEDESEALETLFSEYLLPWCGAFLGKVEAHATTPFW
                     RTMAPLTRDAISAMWDELEEDFEE"
     gene            4375..4866
                     /locus_tag="IRB70_004526"
     CDS             4375..4866
                     /locus_tag="IRB70_004526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415554.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1097 domain-containing protein"
                     /protein_id="HBC0634358.1"
                     /translation="MNILLSIAITTGILSGIWGWVAVSLGLLSWAGFLGCTAYFACPQ
                     GGLKGLAISAATLLSGVVWAMVIIYGSALAPHLEILGYVITGIVAFLMCIQAKQLLLS
                     FVPGTFIGACATFAGQGDWKLVLPSLALGLIFGYAMKNSGLWLAARSAKTAHREQEIK
                     NKA"
     gene            complement(4930..5763)
                     /gene="csgG"
                     /locus_tag="IRB70_004527"
     CDS             complement(4930..5763)
                     /gene="csgG"
                     /locus_tag="IRB70_004527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgG"
                     /protein_id="HBC0634359.1"
                     /translation="MQRLFLLVAVMLLSGCLTAPPKEAARPTLMPRAQSYKDLTHLPA
                     PTGKIFVSVYNIQDETGQFKPYPASNFSTAVPQSATAMLVTALKDSRWFIPLERQGLQ
                     NLLNERKIIRAAQENGTVAINNRIPLQSLTAANIMVEGSIIGYESNVKSGGVGARYFG
                     IGADTQYQLDQIAVNLRVVNVSTGEILSSVNTSKTILSYEVQAGVFRFIDYQRLLEGE
                     VGYTSNEPVMLCLMSAIETGVIFLINDGIDRGLWDLQNKAERQNDILVKYRHMSVPPE
                     S"
     gene            complement(5790..6206)
                     /gene="csgF"
                     /locus_tag="IRB70_004528"
     CDS             complement(5790..6206)
                     /gene="csgF"
                     /locus_tag="IRB70_004528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgF"
                     /protein_id="HBC0634360.1"
                     /translation="MRVKHAVVLLMLISPLSWAGTMTFQFRNPNFGGNPNNGAFLLNS
                     AQAQNSYKDPSYNDDFGIETPSALDNFTQAIQSQILGGLLSNINTGKPGRMVTNDYIV
                     DIANRDGQLQLNVTDRKTGQTSTIQVSGLQNNSTDF"
     gene            complement(6231..6620)
                     /gene="csgE"
                     /locus_tag="IRB70_004529"
     CDS             complement(6231..6620)
                     /gene="csgE"
                     /locus_tag="IRB70_004529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="curli production assembly/transport protein
                     CsgE"
                     /protein_id="HBC0634361.1"
                     /translation="MKRYLRWIVAAEFLFAAGNLHAVEVEVPGLLTDHTVSSIGHDFY
                     RAFSDKWESDYTGNLTINERPSARWGSWITITVNQDVIFQTFLFPLKRDFEKTVVFAL
                     IQTEEALNRRQINQALLSTGDLAHDEF"
     gene            complement(6625..7275)
                     /gene="csgD"
                     /locus_tag="IRB70_004530"
     CDS             complement(6625..7275)
                     /gene="csgD"
                     /locus_tag="IRB70_004530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator CsgD"
                     /protein_id="HBC0634362.1"
                     /translation="MFNEVHSIHGHTLLLITKPSLQATALLQHLKQSLAITGKLHNIQ
                     RSLDDISSGSIILLDMMEADKKLIHYWQDTLSRKNNNIKILLLNTPEDYPYRDIENWP
                     HINGVFYAMEDQERVVNGLQGVLRGECYFTQKLASYLITHSGNYRYNSTESALLTHRE
                     KEILNKLRIGASNNEIARSLFISENTVKTHLYNLFKKIAVKNRTQAVSWANDNLRR"
BASE COUNT         1887 a         1589 c         1778 g         2087 t
ORIGIN      
        1 caagcctgtc ttgtcgcgaa gaatgtataa agcactaagg taataataat tgcggtctgc
       61 aactatcatc attggtattg tttgtggtgg atttttatat tgacaacagt acagttctta
      121 tatctattaa tgacagaaag ggatctacaa cctacagatt ggtgtagctt tatggaaaaa
      181 gactatttgg gaattagtag tactgtatta gtgagtttat tgtttgggct tgcgttggtt
      241 ttggtgaata gttggttcaa tcagccaacc gttgaggaag ttgttccacg atcaacctat
      301 ctgatggtta tgattgcttt attttttatc gatactgttg catttatttt tatgcagttg
      361 tatttcattt atgaccgtag gcaattttca aactgtatac ttagtttggc ttttctaagt
      421 tgtttgattt actttattaa aaccgtcatt atcattcagc aaattattga ggggcgtttg
      481 acaagcagtg ttgttcaaaa tgacattgca atttattatt tgtttcgtca gatgagtttg
      541 tgcgtattaa tatttctggc attggtaaat aaagttagtg aaaacacaaa acagcgcaat
      601 ttgttttcca aaaaagtgac tttgtgcata actttgtttt ttgttcttgg ggggccgata
      661 gttgctcaca tattttctag ccattatgag agctacgatt tacacattgc cgagttaacc
      721 aatgaaaatg gtcaggtggt ttggaaagcc tcatatgtta ccataatgat tttcatgtgg
      781 ttaaccttgc tttcggttaa tctatacttt aatggtttac gctgtgatat ctggaacggg
      841 gtgtcggtga ttgctttttg tgccgtgctg tacaatatct ctctgttatt tatgagcagg
      901 tatagcgtgt ccatttggta tattagtcgc actattgaag tagtcagtaa gttaaccgtt
      961 ttggtaattt ttatgtgcca tatattcagt gcgctacgag taacaaagga cattgcacat
     1021 cgcgatccct taaccaatat atttaacaga aattattttt ttaatgaact gacggttcaa
     1081 tcagcatcgg ccaaaaaaac accttattgc gtcatgatta tggatattga ccacttcaaa
     1141 aaagtcaacg acacctgggg acatccggtt ggcgatcaag tgataaagac agtggtgaat
     1201 atcattggga aaagcatacg accagatgac cttttagcgc gcgttggcgg cgaagagttt
     1261 ggcgtcttgc tgacggagat cgatactgaa tgtgcgaaag ctttagcgga aaggattcgg
     1321 gaaaatgttg aacgtttaac tggcgataat cctgaatacg ccataccaca aaaagtgacg
     1381 attagtattg gcgctgttgt aacgcagaaa aatgagttaa accctaagga gatctatcaa
     1441 ctggctgata acgcacttta cgaggcgaaa gagaccgggc gtaataaggt ggtagtaaaa
     1501 gaggcagaaa ttcttatcaa ccgcaaggat gatgaatgag tctgtcgcca gttgtcgacc
     1561 tccgcttggg gcttctcatc cccccggtgt gtgcaatata cgaaaaaaaa gcccgtactt
     1621 tcgtacgagc tcttctttaa atatggcggt gaggggggga ttcgaacccc cgatacgttg
     1681 ccgtatacac actttccagg cgtgctcctt cagccactcg gacacctcac caaattgtcg
     1741 ttcctgtctt gctggaacgg gcgctaattt agggaaatca tgacctgagg tcaacaaact
     1801 tttttaaaaa atcgctcgat tattcaaact tcaatcaata tgcagtttta ataagcgaaa
     1861 tttgcttttt ttgccaccga ccacggattt gttatgctgg tggcttttgt agatcataac
     1921 gataagtgcg aataaatttc gcgcaacgct tttcgggagt cagtatggat atcatctttt
     1981 atcacccaac gttcgatacc caatggtgga ttgaggcact gcgcaaagct attcctcagg
     2041 caagagtcag agcatggaaa agcggagata atgactctgc tgattatgct ttagtctggc
     2101 atcctccagt tgaaatgctg gcagggcgcg atcttaaagc ggtgtttgca cttggggcag
     2161 gtgttgattc tattttgagc aagctacagg ctcaccctga aatgctgaag ccttctgttc
     2221 cactttttcg cctggaagat accggtatgg gcgagcaaat gcaggaatat gctgtcagtc
     2281 aggtgctgca ttggtttcga cgttttgacg attaccgcct ccagcaaaat agttcgcatt
     2341 ggcaaccgct gcctgaatat catcgggaag attttaccat cggcattttg ggcgcaggcg
     2401 tactgggcag taaagttgca cagagtctgc aaacctggtg ctttccgctg cgttgctgga
     2461 gtcgaacccg taaatcgtgg cctggcgtgc aaagctttgc cggacgggaa gaactgtctg
     2521 catttctgag ccaatgtcgg gtattgatta atttgttacc gaatacccct gaaaccgtcg
     2581 gcattattaa tcaacaatta ctcgaaaaat taccggatgg cgcgtatctc ctcaacctgg
     2641 cgcgtggtgt tcatgtcgtg gaagatgacc tgctcgcggc gctggatagc ggcaaagtta
     2701 aaggcgcaat gctggatgtt tttaatcgtg aacccttacc gccggaaagt ccgctctggc
     2761 aacatccacg cgtgacgata acaccacatg tcgccgcgat tacccgtccc gctgaagctg
     2821 tggattacat ttcgcgcacc attgcccagc tcgaaaaagg ggagagggtc tgcgggcaag
     2881 tcgaccgcgc acgcggctac taataaagca tcaggtttcc tgctatcctt ggcgggaatt
     2941 gaatacagga gagagttatg tatcccgtcg accttcatat gcataccgtt gccagcacgc
     3001 atgcatatag cacattgagt gattacattg cccaggccaa acaaaagggc attaaacttt
     3061 ttgcgatcac cgatcatggc ccggatatgg aagatgcgcc gcatcactgg cacttcatta
     3121 acatgcgtat ctggccgcga gtggttgatg gagtagggat cctgcgcggc atcgaagcta
     3181 acattaaaaa tgttgatggt gaaattgatt gcagcggcaa aatgtttgat tcgctggatc
     3241 tgattattgc cggttttcat gagccggttt ttgcgccgca tgataaagcg accaatacac
     3301 aagcgatgat cgccactatc gccagcggca atgtgcatat aataagccat cccggaaatc
     3361 cgaaatatga aatagatgtt aaagccgttg ctgaagcagc cgcgaaacat caggtggcgc
     3421 tggaaatcaa taattcctct tttttacact cacgtaaggg aagtgaagac aattgtcgtg
     3481 cggtagccgc agcggtacgt gacgctggag gttgggtggc attaggctcg gattctcaca
     3541 ccgcgtttac catgggtgaa tttgaagagt gtcttaaaat cctcgacgcg gtagattttc
     3601 cgccagagcg cattttgaat gtttctccgc gccgcttact gaacttcctt gaatctcgcg
     3661 gtatggcacc gattgcggaa tttgcagacc tttaattact agtaatggaa atatattaat
     3721 gaacgagttt tctatcctct gtcgtgtgct gggttcgctc tattaccgcc aaccacaaga
     3781 tcctttactg gtgccgctgt ttaccctgat tcgtgagggg aaactggctg cgaactggcc
     3841 actggagcag gatgagttgc tgacacgttt gcagaaaagc tgtgatatga cgcaagtctc
     3901 tgccgattac aatgcgttgt ttatcggcga tgaatgtgct gtgccgccat atcgtagcgc
     3961 atgggttgag ggcgcgacgg aagcggaagt gcgcgctttt ctttccgaac gggggatgcc
     4021 attagcggat acgccagccg atcacatcgg cacattgctg ctcgcggctt cctggctgga
     4081 agatcagtca acggaagatg agagcgaagc actggaaaca ctgttcagtg agtatctgtt
     4141 accctggtgt ggtgcgttcc ttggtaaagt ggaggcccat gcaactacgc ctttttggcg
     4201 caccatggca ccgctaaccc gcgatgctat tagtgcaatg tgggacgagc tggaagaaga
     4261 ttttgaagag taaatgtgat ctgcatcact cataactgca acagataatt tgttgttgca
     4321 taaaatgtgt gctcgatctc attcatggcc gcgttttctg atatcatgcg cggcatgaac
     4381 atacttctct ctattgcaat cacaacaggt attctctccg gtatctgggg atgggtggct
     4441 gtttccctgg gcttactaag ctgggcgggc ttcctgggct gtacggccta ctttgcctgc
     4501 ccgcaaggtg ggctgaaagg gctggcgatc tccgctgcaa ccctgcttag tggcgtggtg
     4561 tgggcgatgg tcattattta cggtagtgca ctggcaccac atctggaaat tctcggttat
     4621 gtcataaccg gtattgtcgc gtttctgatg tgtattcagg cgaaacagct gctgctttca
     4681 tttgttccgg ggacgtttat aggcgcatgc gcgacgtttg ccgggcaggg tgactggaaa
     4741 ctggtgttac cttcgctggc gcttgggctg atatttggtt acgcaatgaa aaacagcggc
     4801 ctgtggctgg cggcgcgtag tgcaaagacg gcgcaccgtg agcaggaaat caaaaataaa
     4861 gcgtgagggg cactcacgct ttcgcttaaa ccgtaaaatg ccggatgata attccggctt
     4921 ttttatctgt caggattccg gtggaaccga catatggcgg tatttcacca gaatgtcgtt
     4981 ctgccgttct gctttgttct gcaaatccca cagaccacgg tcaataccat cattaatcag
     5041 gaaaatgacc cctgtttcga tagccgacat caggcacagc ataacgggtt cgttcgaggt
     5101 gtaacccact tccccttcca gcaagcgctg gtagtcaata aagcggaaaa ccccggcctg
     5161 aacttcatag gaaagtatcg tcttactggt gttcaccgag gagaggatct caccggtact
     5221 cacattgacg acacgcaagt tcacggcaat ctgatcaagc tggtattgcg tgtcggcacc
     5281 gatcccaaaa tatcttgccc caacaccgcc cgatttaacg ttgctttcat aaccgataat
     5341 cgaaccttca accatgatat ttgccgccgt taaagactgc agcgggattc ggttattaat
     5401 ggcaaccgta ccgttttctt gtgccgcacg aataatcttg cgctcgttaa gcaggttttg
     5461 taagccctgg cgctccagcg gtataaacca gcgagaatct ttcaatgccg tgaccagcat
     5521 tgccgtggcg ctttgcggaa cagcagtgga gaagttactt gccgggtaag gtttaaattg
     5581 cccggtttcg tcctgaatgt tgtataccga aacaaagatc ttacccgtcg gcgctggcag
     5641 atgggtcaaa tctttgtagc tctgagcacg aggcattaat gtcggtctgg ctgcttcttt
     5701 aggcggggcg gttaagcatc cgctcagtaa catgacggca accaaaagaa ataagcgctg
     5761 catgattatt ttccttatga agctggggct taaaaatcgg ttgagttatt ttgtaaaccc
     5821 gaaacctgga tggtcgaggt ttgtccggtt ttacgatctg tcacgttcaa ctgcaattga
     5881 ccatcgcggt tagcaatatc aacaatataa tcgttggtca ccatgcggcc cggtttaccg
     5941 gtattaatat tcgacagtag cccacctaaa atttgtgact ggatggcctg agtaaagtta
     6001 tctaacgctg agggtgtttc aataccaaag tcatcgttat agctcggatc tttatacgag
     6061 ttttgggcct gggcgctatt taataaaaaa gcgccattat ttgggttacc accaaagttt
     6121 ggattacgga actgaaaagt cattgttcca gcccaactta atggcgaaat aagcatgagt
     6181 agaactactg catgtttgac acgcattgca gcctccgaac aattttttat ttagaattca
     6241 tcatgcgcca aatcgcccgt acttaataac gcctgattta tctggcgacg atttagtgct
     6301 tcttcagttt gaatcagtgc aaagacgaca gttttttcga agtctctttt caacgggaat
     6361 aaaaaagtct ggaaaataac gtcctgattg accgttatag tgatccagct tccccatcgt
     6421 gcactgggcc tttcattaat cgttaagtta cccgtatagt cactttccca tttatcacta
     6481 aaggctcggt aaaaatcatg gccaatagat gaaacagtat ggtcagttaa caatcccggg
     6541 acttctacct caacggcgtg aagattccct gcggcgaaca gaaattctgc cgccacaatc
     6601 cagcgtaaat aacgtttcat ggctttatcg cctgaggtta tcgtttgccc aggaaaccgc
     6661 ttgtgtccgg ttttttacag ctatcttctt gaaaaggtta taaagatgcg ttttaaccgt
     6721 attttcgctg atgaacaacg aacgagcgat ctcgttatta gacgcgccga tacgcagctt
     6781 attcaggatc tctttttccc gatgagtaag gagggctgat tccgtgctgt tataacgata
     6841 gttacccgaa tgcgtaatca ggtagctggc aagcttttgc gtaaagtagc attcgccgcg
     6901 caggacgcct tgcaacccat tgacaacacg ttcttgatcc tccatggcat aaaaaacgcc
     6961 gttgatatga ggccagtttt caatgtcgcg gtacgggtaa tcttcaggcg tatttagcaa
     7021 caatattttg atattgttgt ttttcctgct caaagtatcc tgccaataat ggataagctt
     7081 tttatccgct tccatcatat ccagaagaat aatagagcct gaagagatat cgtccagaga
     7141 acgttgaata ttatgtaatt ttcctgtaat tgccagcgat tgtttaaggt gctgcaagag
     7201 agctgtcgcc tgcaaagaag gtttagtgat caacaataat gtatgaccat gaatactatg
     7261 gacttcatta aacatgatga aaccccgctt ttttttattg atcgcacacc tgacagctgc
     7321 ctctaaaata gaagcaccag a
//
LOCUS       DADXDL010000151         7334 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.151, whole genome shotgun sequence.
ACCESSION   DADXDL010000151 DADXDL010000000
VERSION     DADXDL010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7334)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7334)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7334
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.151"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..515)
                     /locus_tag="IRB70_004531"
     CDS             complement(<1..515)
                     /locus_tag="IRB70_004531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inovirus Gp2 family protein"
                     /protein_id="HBC0634363.1"
                     /translation="MTYKYNPFWQQRIRETVRHALNVHPRLTALRVDLRLPDVPAATD
                     AAVISRFINALKARIDAYQKRKHREGKRVHPTTLHYVWAREFGECKGKKHYHLMLLVN
                     RDTWCRAGDYRAPESLAGMIKQAWCSALGVDVGCHATLVHFPAWPAVWLARNDDTGFQ
                     QVLERADYLAK"
     gene            complement(1256..1381)
                     /locus_tag="IRB70_004532"
                     /pseudo
     CDS             complement(1256..1381)
                     /locus_tag="IRB70_004532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000850858.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin activation protein"
     gene            complement(1733..1999)
                     /locus_tag="IRB70_004533"
     CDS             complement(1733..1999)
                     /locus_tag="IRB70_004533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000840368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634364.1"
                     /translation="MAEPYRYTGWLLRKDASARTRDKEGIVFVRTGREAGVLIIAELF
                     SVVVTVSQPVPGEEETDITDGIRLSDWYYKYKKSSESNVKDLPE"
     gene            2140..2346
                     /locus_tag="IRB70_004534"
     CDS             2140..2346
                     /locus_tag="IRB70_004534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000235222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AlpA family transcriptional regulator"
                     /protein_id="HBC0634365.1"
                     /translation="MATPVSLMDDQMVDMAFITQLTGLTDKWFYRLIRDGAFPAPIKL
                     GRSSRWLKSEVEAWLQARIAQPRP"
     gene            2441..3043
                     /locus_tag="IRB70_004535"
     CDS             2441..3043
                     /locus_tag="IRB70_004535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634366.1"
                     /translation="MKQQYQTRYEWLHESYQKWLTGFTRHAVSWGVCHPNIYYFHNLT
                     PGWVSFNGEKPEIAIVPQSLHRLIYGPDKRATPPLDDDLIVNLCTSEHLLVHHPMLEG
                     ILLSECERLRQRSLANKLISLFRQFGGTELRLKLVWLCWLDLMTGNSLEDWKENLKRK
                     SEKELEEWIINRQRQSAALTDLMDQYVLLAYRTTVDDSRN"
     gene            3215..3412
                     /locus_tag="IRB70_004536"
     CDS             3215..3412
                     /locus_tag="IRB70_004536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015953093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634367.1"
                     /translation="MFFTARYTPGSQQTECAGAVIHQKWHAAVHTHPGDNMYVATAIP
                     ALWKRLTQPAGYSFRHPGMSA"
     gene            4244..5161
                     /locus_tag="IRB70_004537"
     CDS             4244..5161
                     /locus_tag="IRB70_004537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634368.1"
                     /translation="MVQKILSDKVMNERANAYYSYYLGERNISVLPLNVYDPPERFIA
                     YIKKNRENLNITLSDFELEQIISGMRLKALAFLVPLEKISWIAGSERACLFSWYLLMQ
                     FIQNNRAKISADLLQKNKLYLKEEYLEGNAFPSDSSTQFRQILRVLDILSDKNLRDEW
                     IIQTKDRWIRAFKSKSPFSYLLPENEHECIWTWNYLKGKNIALEKLASFPGSADIYHA
                     IHLSFDIWVTCTLTSPDDIKNFRNSFNKAKAQRKYKKMQEDKVNVQFFLDAETRAQLK
                     ELSRVRRLSTGEMLHDLIVEEYKRYRHSR"
     gene            5246..6118
                     /locus_tag="IRB70_004538"
     CDS             5246..6118
                     /locus_tag="IRB70_004538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase family protein"
                     /protein_id="HBC0634369.1"
                     /translation="MNPSDAIEAIEKPLSSLPYSLSRHIQEHLRKLTSHEPVIGIMGK
                     SGAGKSSLCNALFQGEVTPVSDVHAGTREVRRFRLSGHGHSMIITDLPGVGESRDRDA
                     EYEALYRDILPELDLVLWLIKADDRALSVDEYFWRHILHRGHQQVLFVVTQADKTEPC
                     HEWDMAGIQPSPAQAQNIREKTEAVFRLFRPVHPVVAVSACTGWELDTLVSALMTALP
                     DHAASPLMTRLQDELRTESVRSQAREQFTGAVDRIFDTAESVCVASVARTVLRAVRDT
                     VVSVARAVWNWIFF"
     gene            6490..>7334
                     /gene="ag43"
                     /locus_tag="IRB70_004539"
     CDS             6490..>7334
                     /gene="ag43"
                     /locus_tag="IRB70_004539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HBC0634370.1"
                     /translation="MKRHLNTSYRLVWNHITGTLVVASELARSRGKRAGVAVALSLAA
                     VTSVPALAADKVVQAGETVNDGTLTNHDNQIVLGTANGMTISTGLEYGPDNEANTGGQ
                     WIQNGGIANNTTVTGGGLQRVNAGGSVSDTVISAGGGQSLQGQAVNTTLNGGEQWVHE
                     GGIATGTVINEKGWQAIKSGAVATDTVVNTGAEGGPDAENGDTGQTVYGDAVRTTINK
                     NGRQIVAAEGTANTTVVYAGGDQTVHGHALDTTLNGGYQYVHNGGTASGTVVNSDGWQ
                     IVKNGG"
BASE COUNT         1794 a         1884 c         1848 g         1808 t
ORIGIN      
        1 tccttcgcca gatagtcagc acgttccagc acctgctgaa agccggtgtc atcattacgc
       61 gccagccaca ccgccggcca ggccggaaaa tgcaccagcg tggcatggca cccgacatcc
      121 actcccaggg cactgcacca cgcctgttta atcatcccgg ccagagactc cggagcgcgg
      181 taatcaccgg cacgacacca ggtatcccgg ttgaccagca gcatcaggtg atagtgtttt
      241 ttacctttgc actccccaaa ctcccgggcc cagacgtaat gcagggttgt gggatgcacg
      301 cgtttacctt cccgatgctt acgtttctgg taagcgtcga ttcgggcttt cagggcattg
      361 atgaagcggg atatcacagc tgcgtccgtt gctgccggta catccgggag acgcaggtca
      421 acccgcaatg ccgtcaggcg gggatgaaca ttcagtgcgt gccgcaccgt ctcacgaata
      481 cgttgctgcc agaaggggtt gtatttgtag gtcatggtta aatctccgta tggttcatac
      541 ggaatagcca cgtcgtaaaa aatacgcaga gtccctgaag tgacctccgg caggacactg
      601 tctcaggcac tctgtgataa cccgaacggt cgtctccgga ctgacgattg aattcccggc
      661 gttgtttttt ttaatgtaaa aaaccggtta cggataaggc gtggcgaggg agctatcgtg
      721 atacgcaaaa agaaatgcgg ggattgcggt aattcgatta ctcataatac agtgtgttgc
      781 ctgtattgtg gcgctgtcgt tccttccggt tattaccgga agaccgatcg tctgctctgt
      841 ttactgagtt actgctggtg ctgattctgg ttaccgtttc aggcgtcagt gtatttgtac
      901 tgttgcagta ggttactggg gagggattat caggaatcgg cggagcagag cgactcgctg
      961 cgtttgttgt gccagacagt aacgcaccgg atccctgcaa aatggtacct gaatcaatca
     1021 cagttaggta ttccgccaat ccgtgatcga atcgagcgga atacgcagcc ccgacaaata
     1081 cgagccccct tcagcagata caggccggta atacctgaaa atcagcctat taccgcccac
     1141 gcctccggca ccattccctt ttgatttcga attctttgtt gtcgctatac cgcttaatgt
     1201 tcccggcacc tccggtgcag ataacaccgg agtcatcgta gcgctgcttc aatattcagg
     1261 tgacatattt ccagacggaa gccggcgcgc gatcgtaaag tttgttcatt gtcagttctg
     1321 ccagccggtt gtcaacggca gagttaaagg cttccagctc cgcaagggta agtttataac
     1381 gcgtgtggga attcactttt cccgcgtctc ctgacgtatt acgggctgcc acttaccagg
     1441 tgtcccgcaa tacagcctta gtgttccgtt atcggggatc cggacgcacc gcaacaaccg
     1501 gggaagtatt tctggtttag agcagtgtca agagggattt ctcagcccct cactcaccgg
     1561 ctcagtctca gggcaggagc attaatacgc tcagttcatg tcttatacag gaatgggcac
     1621 agggggagct ggcgtgtcac tgctgatttt acgcatcagc gttcatgtat ctgcactctg
     1681 atacatgaac gattcacagc gctctgttac cggagagatt tactctctta gcttactctg
     1741 gcaaatcctt tacgttactc tctgatgact tcttatattt ataataccaa tcagacagcc
     1801 ttatcccatc ggtgatatca gtctcctcct cgccaggaac gggctgactc actgtaacca
     1861 ccaccgaaaa caactctgca attatcagaa cgcctgcttc tctccctgtc ctcacgaaaa
     1921 ctatcccctc tttatcgcgc gtgcgtgcgg aagcatcttt tcgcaacaac cacccggtat
     1981 accggtacgg ctcagccacc gcaacctccc cgtttatctc ctggcggtca cattcccgat
     2041 tattttttac gtttctcccc ggttgttatg ccggtgaagg tggcgcgctg ttttcatgac
     2101 cacaccggct ggtttaacaa catccggagg aacattctca tggctacccc agtttcactg
     2161 atggatgacc agatggtcga catggcattt atcactcaac tgaccggcct gacagataag
     2221 tggttttaca ggctcatcag ggatggggcc tttccggctc ccatcaagct gggccgcagc
     2281 tcccgctggc tgaaaagtga agtggaagcc tggctgcagg cgcgtattgc acagccccgc
     2341 ccgtaatttc tgaccgttat ccgttcaccc gcagcagacg taatccccgg cctgccggcg
     2401 gcattctgct gcctgttata tccccgtgag gaatatgaaa atgaaacaac agtatcagac
     2461 ccgctacgaa tggctccacg aaagctacca gaaatggctg accggcttca cccggcacgc
     2521 cgtatcctgg ggcgtgtgtc atccgaatat ctactacttc cataatctga cgcccggttg
     2581 ggtgtcattc aatggtgaaa aaccggagat tgccatcgta ccccagagcc tgcaccggct
     2641 gatttatggc cctgacaaac gggccacgcc gcccctggat gatgatctga ttgtgaattt
     2701 atgcaccagt gaacatctgc tggttcatca tccgatgctg gaaggcattc tcctgtctga
     2761 atgtgaacgt ctgaggcagc gttctctggc aaataaactg atcagcctct tccgtcagtt
     2821 tggtggcacg gagttgcgcc tcaaactggt ctggctttgc tggcttgatt taatgaccgg
     2881 aaacagcctt gaagactgga aagagaacct gaaacggaaa tcagaaaaag agctggagga
     2941 atggatcatc aaccgtcaga ggcagagcgc agcactgacg gatctgatgg atcagtacgt
     3001 gctcctggca taccgcacaa cggttgacga tagccgcaac tgatgccggt tgcttccgga
     3061 aggtgtgaca aaatacggaa atgatgatgc tcccggcccc gcatgctcac ctgcagagcg
     3121 tgttcgtcgt catcatactg agccatgacg ggcgtcttaa gggcatcctg tcattgctga
     3181 gcaggcaaca ccaccagagg agccacggac agggatgttc tttacagccc gatacacgcc
     3241 aggttctcag cagactgaat gtgcaggtgc ggttattcac cagaaatggc atgctgcggt
     3301 acatacccat cctggtgaca atatgtacgt ggcgacagcg atcccggcac tgtggaagag
     3361 actcactcag cctgcaggat attctttccg gcatccggga atgtccgcct gaatgcaaac
     3421 aggatgatat ttgaatccgt aatactgttc tttcatcata aataatttat gcagatacag
     3481 ttaaccgtta cagtagccgg tttgttttac cgggaaataa tatccgtcag actgatgccg
     3541 gaacatatct gaaacacgtt atgatgtttt gttatcagaa atgttgtata ttcttatccg
     3601 tggcgacagt ttaatgccct ctggtatcac ctgataatgc atatcctgcg atgattcgtt
     3661 atatttacgg gacacgcctc ttttcattgt gctccttttc agacttcatt ttccgtaagt
     3721 gttccccggc ataaaggagg tacctttctg gcgtttataa ctctctttat cggtgacgcc
     3781 ggtaatacag ggaataccac accgacaaac gaggtattaa cagacgatat ttcagtgtcc
     3841 ataatttttc tgtccggtta aataacgtca gtctgctgcc ctctgactgt aatcatcaaa
     3901 gccggaatgc ataccgggtt acaacgtaaa aaaagtgatg ctggcccccg gtgcagctgg
     3961 cgggcgaaac atgtttacct ttcaataccc cctgtctgca gtctccactc ttccatcctc
     4021 ttaagctacg tcggccacat gagtgcactt ccatgataac aggtattcct gtcagcataa
     4081 cgaagccggt taccttccct tcctcctgca tttcctgtca gaatgactgt acagcgcgca
     4141 gattgccttt ttattgacca ccttaacata ccattataaa cttcttttta tcatgttatt
     4201 atcaccttat tatgtttaat tttcaagcaa ccggagaaag aggatggttc agaaaatttt
     4261 gtcggataag gttatgaatg aaagagcaaa tgcgtattac tcttattatc ttggagagcg
     4321 taatatctcc gtactgcccc ttaatgttta tgatcccccg gaacgtttta tcgcttacat
     4381 aaaaaaaaac agagaaaatc tgaacatcac actttcagat tttgaacttg aacaaatcat
     4441 ttctggtatg cgtctgaagg ccctggcctt cctggtcccc ctggaaaaaa tatcctggat
     4501 cgcgggcagt gaacgcgcat gcttattttc ctggtatctg ttgatgcagt ttatccagaa
     4561 taacagggca aaaataagcg cagacttgct tcaaaagaat aaactgtatc ttaaagaaga
     4621 gtatctggaa gggaatgcct tcccgtcgga ctcatcgaca cagttcagac aaatactcag
     4681 agttctcgat attctttctg ataagaattt gcgggatgag tggataatcc agaccaaaga
     4741 cagatggata cgggcattta aatcaaagag tcctttcagt tacctcctcc cggagaacga
     4801 acatgaatgc atatggacat ggaattattt gaagggaaaa aatattgcac tggaaaaact
     4861 ggccagtttt cctggttctg ctgatattta ccacgcaatt cacctttcat ttgacatatg
     4921 ggttacctgt acactcacct cacctgacga tataaaaaat ttcagaaaca gtttcaataa
     4981 ggccaaggcg cagcgcaagt acaaaaaaat gcaggaagat aaagtcaatg tacagttttt
     5041 tcttgacgca gaaaccaggg cgcagctcaa agaattatcg agggtcagaa gactcagtac
     5101 cggcgaaatg ctgcatgacc tgattgttga agagtataaa aggtaccgac attccagata
     5161 atttcagaca tatattatct ctgtgagtcc cccgccacct ttccggtgtg cgggggtttt
     5221 gtcttttttc accgggaata catgtatgaa tccgtctgat gccattgagg caattgaaaa
     5281 accgctctcc tccctgcctt actcactttc ccgtcacatc caggaacatc tgcgcaaact
     5341 caccagtcac gaacccgtga ttggcattat gggtaaaagc ggggccggta aatcctcact
     5401 ctgtaatgca ctgtttcagg gggaggtcac cccggtcagt gatgttcacg ccggcacccg
     5461 ggaagtgcgg cgcttccgtc tgagtggcca cggtcacagc atgattatca ctgacctgcc
     5521 cggggtgggc gagagccggg acagggatgc agagtatgaa gccctgtacc gtgacattct
     5581 gcctgaactt gacctggtac tgtggctgat taaagccgat gaccgtgccc tgtctgtgga
     5641 tgagtatttc tggcgacaca tcctgcaccg gggacatcag caggtgctgt ttgtggtgac
     5701 gcaggccgac aaaacggagc cctgccatga atgggatatg gccggcattc agccttctcc
     5761 cgcacaggca cagaacattc gtgagaaaac ggaggcggta ttccggctgt tccggcccgt
     5821 acatccggtt gtggccgtat cggcctgcac cggctgggaa ctggatacgc tggtcagtgc
     5881 gctcatgaca gcgcttcccg accatgccgc cagtcccctg atgacccgcc tgcaggacga
     5941 gctgcgcacg gaatctgtcc ggtctcaggc ccgtgaacag tttaccggtg cggtggaccg
     6001 gatatttgac acggcggaga gcgtctgtgt tgcctctgtt gcccgtacgg ttctgcgtgc
     6061 cgtccgtgac acggtggtct ctgttgcccg cgctgtatgg aactggattt tcttctgaac
     6121 agtctgccag ggaaatgcct gataacatta cgttaaccaa ctgaaaacat gacacaaacc
     6181 cctcatactc ctcctgtttc tcttgcgtga ccgccttgtc gttaatagaa taaaacgatc
     6241 gataaaacag gtatcgatcg ttactatcga tcgtttatag tggttaatgg tctgcgaaaa
     6301 ggcagctgaa tctcttcatc atgcagaacg gaattgcaca caacggactg atacttctct
     6361 ggcggatgag agaggggaag catttatgtc cgggaaaaac cactttatct gagcatgctg
     6421 ttttgtacct gccggtatcc acatttgtgg gtaccggctt ttttattcac cctctgtaag
     6481 gaaaagctga tgaaacgaca tctgaacacc agctacaggc tggtatggaa tcacattacg
     6541 ggcaccctgg tggtggcctc cgaactggcc cgctcacggg gaaaacgcgc tggtgtggcg
     6601 gttgcgctgt ctcttgctgc tgtcacatca gtcccggcac tggctgctga caaggttgta
     6661 caggcgggag aaaccgtgaa cgacggaaca ctgacaaatc atgacaacca gattgtcctc
     6721 ggtacggcca acggaatgac catcagtacc ggtctggagt atgggccgga taacgaggcc
     6781 aataccggcg gacaatggat acaaaatggc ggtatcgcca acaacactac tgtcaccggt
     6841 ggtggtcttc agagagtgaa tgccggagga agcgtttcag acacggttat cagtgccgga
     6901 ggcggacaga gccttcaggg gcaggcagtg aacaccactc tgaacggcgg tgagcagtgg
     6961 gtacatgaag gcgggattgc aacgggtacc gtcattaatg agaagggctg gcaggccatc
     7021 aaatccggcg cagtggcaac cgacacggtt gtgaataccg gcgcggaagg gggaccggat
     7081 gcggaaaatg gtgataccgg gcagaccgtc tacggagatg ccgtacgcac caccatcaat
     7141 aaaaatggtc gtcagattgt ggctgctgaa ggaacggcaa ataccactgt ggtttatgcc
     7201 ggcggcgacc agactgtaca tggtcacgca ctggatacca cgctgaatgg ggggtaccag
     7261 tatgtgcaca acggcggtac ggcgtctggc actgttgtaa acagtgacgg ctggcagatt
     7321 gtcaaaaacg gggg
//
LOCUS       DADXDL010000152         7310 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.152, whole genome shotgun sequence.
ACCESSION   DADXDL010000152 DADXDL010000000
VERSION     DADXDL010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7310)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7310)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7310
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.152"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            251..1021
                     /locus_tag="IRB70_004540"
     CDS             251..1021
                     /locus_tag="IRB70_004540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418784.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter ThrE family protein"
                     /protein_id="HBC0634371.1"
                     /translation="MQTEQQRAVTRLCIQCGLFLLQHGAESALVDELSSRLGRALGMD
                     SVESSISSNAIVLTTIKDGQCLTSTRKNQDRGINMHVVTEVQHIVILAEHHLLDYKGV
                     EKRFSQIQPLRYPRWLVALMVGLSCACFCKLNKGGWDGAVITFFASTAAMYIRQLLAQ
                     RHLHPQINFCLTAFAATTISGLLLQLPTFSNTPTIAMAASVLLLVPGFPLINAVADMF
                     KGHINTGLARWAIASLLTLATCVGVVMALTIWGLRGWV"
     gene            1012..1485
                     /locus_tag="IRB70_004541"
     CDS             1012..1485
                     /locus_tag="IRB70_004541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418783.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter"
                     /protein_id="HBC0634372.1"
                     /translation="MGVIEFLFTLAQDMILAAIPAVGFAMVFNVPVRALRWCALLGAI
                     GHGSRMILMTSGLNIEWSTFMASMLVGTIGIQWSRWYLAHPKVFTVAAVIPMFPGISA
                     YTAMISAVKISQLGYSESLMITLLTNFLTASSIVGALSIGLSIPGLWLYRKRPRV"
     gene            1593..2132
                     /gene="dnaT"
                     /locus_tag="IRB70_004542"
     CDS             1593..2132
                     /gene="dnaT"
                     /locus_tag="IRB70_004542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaT"
                     /protein_id="HBC0634373.1"
                     /translation="MSSRVLTPDVVGIDALVHDHQTVLAKAEGGVVAVFANNAPAFYA
                     VTPARLAELLALEEKLARPGSDVALDDQLYQEPQAAPVAVPMGKFAMYPDWQPDADFI
                     RLAALWGVALREPVTTEELASFIAYWQAEGKVFHHVQWQQKLARSLQIGRASNGGLPK
                     RDVNTVSEPDSQIPPGFRG"
     gene            2135..2872
                     /gene="dnaC"
                     /locus_tag="IRB70_004543"
     CDS             2135..2872
                     /gene="dnaC"
                     /locus_tag="IRB70_004543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication protein DnaC"
                     /protein_id="HBC0634374.1"
                     /translation="MKNVGDLMQRLQKMMPAHIKPAFKTGEELLAWQKEQGAIRSAAL
                     ERENRAMKMQRTFNRSGIRPLHQNCSFENYRVECEGQMNALSKARQYVEEFDGNIASF
                     IFSGKPGTGKNHLAAAICNELLLRGKSVLIITVADIMSAMKDTFRNSGTSEEQLLNDL
                     SNVDLLVIDEIGVQTESKYEKVIINQIVDRRSSSKRPTGMLTNSNMEEMTKLLGERVM
                     DRMRLGNSLWVIFNWDSYRSRVTGKEY"
     gene            2921..3415
                     /locus_tag="IRB70_004544"
     CDS             2921..3415
                     /locus_tag="IRB70_004544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418780.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2501 domain-containing protein"
                     /protein_id="HBC0634375.1"
                     /translation="MMKTVKHLLCCAIAASALISTGVHAASWKDALSSAASELGNQNS
                     TTQEGGWSLASLTNLLSSGNQALSADNMNNAASILQYCAKQKLASVTDAENIKNQVLE
                     KLGLNSEEQKEDTNYLDGIQGLLKTKDGQQLNLDNIGTTPLAEKVKTKACDLVLKQGL
                     NFIS"
     gene            3669..5960
                     /gene="opgB"
                     /locus_tag="IRB70_004545"
     CDS             3669..5960
                     /gene="opgB"
                     /locus_tag="IRB70_004545"
                     /EC_number="2.7.8.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418779.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerol--membrane-oligosaccharide
                     glycerophosphotransferase"
                     /protein_id="HBC0634376.1"
                     /translation="MSELLSFALFLASVLIYAWKAGRNTWWFAATLTVLGLFVVLNIT
                     LFASDYFTGDGINDAVLYTLTNSLTGAGVSKYILPGIGIVLGLTAVFGALGWILRRRR
                     HHPHHFGYSLLALLLALGSVDASPAFRQITELVKSQSRDGDPDFAAYYKEPSKTIPDP
                     KLNLVYIYGESLERTYFDNEAFPDLTPELGALKNEGLDFSHTQQLPGTDYTIAGMVAS
                     QCGIPLFAPFEGNASASVSSFFPQNICLGDILKNSGYQNYFVQGANLRFAGKDVFLKS
                     HGFDHLYGSEELKSVVADPHYRNDWGFYDDTVLDEAWKKFEELSRSGQRFSLFTLTVD
                     THHPDGFISRTCNRKKYDFDGKPNQSFSAVSCSQENIATFINKIKASPWFKDTVIVVS
                     SDHLAMNNTAWKYLNKQDRNNLFFVIRGDKPQQETLAVKRNTMDNGATVLDILGGDNY
                     LGLGRSSLSGQSMSEIFLNIKEKTLAWKPDIIRLWKFPKEMKEFTIDQQKNMIAFSGS
                     HFRLPLLLRVSDKRVEPLPESEYSAPLRFQLADFAPRDNFVWVDRCYKMAQLWAPELA
                     LSTDWCVSQGQLGGQQIVQHVDKTTWKGKTAFKDTVIDMARYKGNVDTLKIVDNDIRY
                     KADSFIFNVAGAPEEVKQFSGISRPESWGRWSNAQLGDEVKIEYKHPLPKKFDLVITA
                     KAYGNNASRPIPVRVGNEEQTLVLGNEVTTTTLHFDNPTDADTLVIVPPEPVSTNEGN
                     ILGHSPRKLGIGMVEIKVVEREG"
     gene            complement(6097..7119)
                     /gene="lgoD"
                     /locus_tag="IRB70_004546"
     CDS             complement(6097..7119)
                     /gene="lgoD"
                     /locus_tag="IRB70_004546"
                     /EC_number="1.1.1.414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418778.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-galactonate oxidoreductase"
                     /protein_id="HBC0634377.1"
                     /translation="MSTMNVLICQQPKELVWKQREIPIPGDNEALIKIKSVGICGTDI
                     HAWGGHQPFFSYPRVLGHEICGEIVGLGKNIADLKNGQQVAVIPYVACQQCPACKSGR
                     TNCCEKISVIGVHQDGGFSEYLSVPVANILPADGIDPQAAALIEPFAISAHAVRRAAI
                     APGEQVLVVGAGPIGLGAAAIAKADGAQVVVADTSPARREHVATRLELPVLDPSAEDF
                     DAQLRAQFGGSLAQKVIDATGNQHAMNNTVNLIRHGGTVVFVGLFKGELQFSDPEFHK
                     KETTMMGSRNATPEDFAKVGRLMAEGKITADMMLTHRYPFATLAETYERDVINNRDLI
                     KGVITF"
BASE COUNT         1824 a         1905 c         1815 g         1766 t
ORIGIN      
        1 aacgcgccca gttatctttt atcctgattc gtaaaggcta aagaataaat tcattatagt
       61 gataatattc atgtgataat ttgtttgcgg cgagagataa ttcccttttt atcaccgagc
      121 ttgtcccgat aaccaggatt aatcagcgca attttgatct taacctaccg caaaactacc
      181 gtgcttcatg atacaaatgg attctcatta tctgaacaat acgcagcacg tctatgacaa
      241 agggcgagtt atgcaaactg agcaacagcg agccgtaaca cggctttgta tccagtgtgg
      301 attatttctt ttgcaacatg gtgcggaaag cgcgttggtt gatgagcttt cctcacgact
      361 gggtcgggcg ttggggatgg acagcgtcga aagttctatc tcttcgaacg ccatagtgct
      421 gacaaccatt aaagatgggc aatgcctgac atcgacacgt aaaaatcaag atcgcggcat
      481 taatatgcat gtggtgactg aagtccagca cattgtgatt ctggcggagc accatctgct
      541 ggattacaaa ggcgtagaga aacgatttag ccaaattcag ccattacgtt acccaagatg
      601 gctggtagcc ttaatggttg gcctttcctg cgcctgtttc tgtaaactca ataaaggtgg
      661 ctgggatggt gccgtcatca ccttctttgc cagtacggcc gcgatgtata tccgccagct
      721 gctggcacaa cgtcatcttc atccacagat caacttttgc cttaccgctt tcgccgccac
      781 caccatttcc ggattgcttt tgcaactccc tactttcagc aataccccca ccatcgcgat
      841 ggccgccagc gttctgctgc tggtgccggg ctttccgttg attaatgccg tcgccgatat
      901 gtttaaaggc cacatcaata ccggactggc acgctgggcg atcgccagtc tgctgacact
      961 ggctacctgc gtcggcgtgg tgatggcact gacgatttgg gggctacgcg gatgggtgtg
     1021 atcgagtttc tgtttacatt ggcgcaggat atgatcctcg ccgccattcc agcggtcggc
     1081 tttgcgatgg tgttcaacgt tcccgttcgg gcgttacgct ggtgtgcgct gcttggcgcg
     1141 attggtcatg gttcacgaat gatcttaatg accagcgggc tgaatattga gtggtcaact
     1201 tttatggctt ctatgctggt cggcaccatt ggtattcaat ggtcgcgctg gtatctggcg
     1261 catccgaaag tgtttaccgt ggcggccgtt atccctatgt tccctggcat atcggcttat
     1321 accgcaatga tttcggcggt aaaaatcagt cagttaggtt acagcgagtc attgatgatt
     1381 accctgttaa ccaactttct tacagcttca tcgattgttg gtgcgttatc catcggtctt
     1441 tccattcctg gattatggtt gtaccgcaag cgccctcgcg tataaaattg cctcgcttaa
     1501 agcacacgga tgagagacag cctcctctcc tccatgtgtt actataaaag ttatctccct
     1561 tctcgttcat cgttccatat ttgagaaaca gtatgtcttc cagagttttg accccggacg
     1621 tcgttggtat tgacgccctg gtacacgatc accaaaccgt tctggcaaaa gctgaaggcg
     1681 gtgtggttgc cgtatttgct aacaatgccc cggcgtttta tgccgtcacg cctgcacgcc
     1741 tggctgaact gctggcgctg gaagaaaagc tggcgcgtcc gggaagcgat gtcgctctgg
     1801 acgatcaact ctatcaggaa ccgcaagccg ctcccgttgc tgtacccatg gggaaattcg
     1861 ccatgtatcc ggactggcaa cccgatgccg actttatccg cctggcggcg ctatggggcg
     1921 tggcgctaag agagccggtg accaccgaag aactggcctc attcattgcc tactggcagg
     1981 cggaaggtaa agtctttcac catgtacagt ggcaacaaaa actggcgcgc agcctgcaaa
     2041 tcggccgtgc cagcaacggc ggactgccga aacgagatgt gaatacggtc agcgaacctg
     2101 acagccaaat tccaccagga ttcagagggt aacgatgaaa aacgttggcg acctgatgca
     2161 acgcctgcaa aaaatgatgc ctgcccatat caaacctgcg tttaaaacgg gtgaagaact
     2221 actggcctgg cagaaagaac aaggggcgat ccgctccgcc gctctcgaac gtgaaaatcg
     2281 ggcgatgaaa atgcagcgca cctttaaccg ctccggtatt cgtccactgc atcagaactg
     2341 ctcctttgag aactatcgcg ttgagtgtga agggcagatg aatgcgttaa gcaaagcgcg
     2401 ccagtatgtc gaagagtttg acggcaacat cgccagcttc atcttttctg gtaagccagg
     2461 aaccggcaaa aaccatctgg cggcggcaat ctgcaacgag ctgctgctac gcggtaaatc
     2521 cgtattgatc atcaccgtgg ccgatattat gtcggcgatg aaagatacct tcaggaatag
     2581 cggtaccagc gaagaacaac tgcttaacga tctgagcaac gttgatctgc tggtgatcga
     2641 tgagatcggc gtgcagaccg aatcgaaata cgaaaaagtg atcatcaacc agatcgtcga
     2701 tcgccgctct tcttccaaac gcccaaccgg gatgctgacc aacagtaata tggaagagat
     2761 gaccaagttg ctgggcgaac gcgtgatgga ccgtatgcgc ctgggtaaca gtttgtgggt
     2821 gatcttcaac tgggatagct accgtagccg tgtaacaggt aaagagtatt aatccccgtt
     2881 tctggcggta tactgcgaca caattccacc ttgagtaatg atgatgaaaa ctgttaaaca
     2941 tcttctgtgc tgtgccattg ccgccagcgc attaatttcc accggggtgc atgctgcgtc
     3001 ctggaaagat gcgctctcca gcgccgccag cgaacttggc aaccaaaaca gcacgacaca
     3061 ggaaggcggt tggtcgctcg cgtcattaac taacttgctt agcagcggga accaggcctt
     3121 aagcgcagat aacatgaaca acgccgcaag cattctgcaa tactgcgcga agcaaaagct
     3181 ggcttcggta accgatgccg aaaacatcaa gaatcaggtg ctggaaaagc tgggcctgaa
     3241 cagtgaagag caaaaagaag acaccaacta tctggacggt attcagggtt tgctgaaaac
     3301 caaagatggt cagcaactca atctggataa catcggaacg actccgctgg cagaaaaggt
     3361 gaaaaccaaa gcctgcgatc tggtgttaaa gcaggggctg aacttcattt cctgaaccgc
     3421 gaaacgccgc gttttagctg ttacccggct gacgcggctc tctcctgccc ttttccctgc
     3481 tcctggacgg ttttccccct gttacacggg aagcgaccgc gatcaaaaaa gtctgtttat
     3541 aaactaattc ctaacaacat cgcatttttt tgacactaga attgcagcaa tatggcgacg
     3601 ccattacatt gtgcttctca aaaagcttaa acgttggcta aacggcccgg tttagtgagg
     3661 atcgcccgtt gtcagaacta ctctctttcg ccctttttct cgcctctgtg ctgatttacg
     3721 catggaaagc gggacgtaac acctggtggt ttgcagccac attaacggtg ctggggctat
     3781 ttgtcgtttt aaatatcacc ctgtttgcca gcgactattt tactggcgat ggtattaacg
     3841 acgcggttct ctatacctta accaacagcc tgaccggtgc tggcgtcagc aaatacatcc
     3901 tgccgggtat cggcattgtg ctggggctga cagcggtgtt cggtgcgctg ggctggatcc
     3961 tgcgccgtcg tcgtcatcat ccgcaccatt ttggttacag cctgctggcg ctcttactgg
     4021 cgctgggttc agtggatgcc agcccggcat ttcgtcagat aacggaactg gtgaaatccc
     4081 agtcacgcga cggcgacccg gactttgcgg cttattataa agagccgtcg aaaactatcc
     4141 ctgacccgaa actcaacctg gtttatatct acggcgaaag tctcgagcga acctattttg
     4201 ataacgaagc tttcccggat ctcacgcctg aactgggcgc gttgaaaaat gaaggcctgg
     4261 atttcagcca cacgcagcag ctgccaggaa cggattacac gattgcgggc atggtggctt
     4321 ctcagtgcgg cataccgctg tttgccccct ttgaaggcaa cgcctccgcc tctgtctcca
     4381 gcttcttccc gcagaacatc tgtctgggcg atatcctgaa aaactcgggt tatcagaact
     4441 atttcgtgca gggcgcgaat ctgcgttttg ccggtaaaga tgtgttcctg aaatcgcacg
     4501 gcttcgacca cttatacggc tcagaagagc tgaaaagcgt ggtggccgac ccgcactatc
     4561 gcaacgactg gggattctac gacgataccg ttctcgatga agcgtggaaa aagtttgaag
     4621 agctttcccg ctcaggtcag cgattctcac tgtttaccct gacggtcgat acccatcacc
     4681 cggatggttt tatctcgcgc acctgtaacc gcaaaaaata tgattttgac ggtaagccta
     4741 atcagtcatt cagcgcggta agttgcagcc aggagaacat cgcgacgttt atcaacaaaa
     4801 tcaaagcgtc accgtggttt aaagataccg tcatcgtcgt ctcttctgac catttagcga
     4861 tgaacaacac ggcgtggaaa tacctcaata agcaggatcg caataacctg ttttttgtca
     4921 ttcgtggcga caagccgcag caagagacgc tggcagtgaa gcgtaacacg atggataacg
     4981 gcgcgacggt gctggacatt ctcggtggcg ataactatct cggacttggt cgtagcagtt
     5041 tatccgggca gtcgatgtcg gaaatcttcc tcaatatcaa agagaaaaca ttggcgtgga
     5101 agccagatat catccgcctg tggaaattcc ctaaagagat gaaagagttc accatcgacc
     5161 agcagaaaaa catgattgcc ttctcgggta gccatttccg tttgccgctg ctgttgcggg
     5221 tttcagacaa acgcgtggaa ccgctgccgg aaagcgaata ctcagcaccg ctgcgtttcc
     5281 agctggccga tttcgctcca cgcgacaatt tcgtctgggt tgaccgttgc tacaagatgg
     5341 cacaactctg ggctccggaa ctggcacttt ccaccgactg gtgtgtctcg caggggcagc
     5401 ttggcggtca gcaaattgtt cagcatgttg acaaaacaac atggaagggc aaaacggcat
     5461 ttaaagatac ggtcatcgac atggcgcgtt acaaaggcaa tgtcgatacg ctgaagattg
     5521 ttgataacga tattcgctac aaagccgaca gtttcatctt taacgtcgcc ggtgcgccag
     5581 aagaagtgaa acagtttagc gggatttccc gtccggagtc gtggggccgc tggtccaacg
     5641 cgcagctggg cgatgaagta aaaatcgagt acaagcatcc gctgccgaag aaatttgacc
     5701 tggtgattac cgccaaagca tacggcaata acgccagccg tcctattccg gtacgcgtag
     5761 gcaatgaaga acaaactctt gtgctgggca atgaagtgac caccaccaca ctgcatttcg
     5821 ataacccaac cgatgccgac acactggtaa ttgtgccgcc ggaacctgtc tcaaccaacg
     5881 aagggaatat cctcggacac tcgccgcgta agctcgggat cggcatggtg gaaattaaag
     5941 tggtagaacg tgaagggtaa ttcctgactg atgtgtaggt cgcataaggt gcgacctaca
     6001 caccttctac ggcttacaac acattattaa gaaacaaaaa aacagcgccc aacacttccc
     6061 cggacgctgc atggcaactt taataatctc gctttatcag aaagtaatta cacccttaat
     6121 caaatcacga ttgttaatca catcgcgctc gtaggtttct gccagcgtgg cgaacggata
     6181 gcgatgggtt aacatcatgt cagcagtgat tttcccttcc gccatcagtc gaccgacttt
     6241 agcgaaatct tccggcgtgg cgttgcggct gcccatcatc gtcgtttctt ttttatggaa
     6301 ttccggatcg gagaactgca actcaccttt aaacaggccg acaaatacca ccgtgccgcc
     6361 gtgacgaatc agattcacgg tgttattcat cgcatgttga ttacctgtcg cgtcgatcac
     6421 tttctgcgcc agcgaaccac caaactgcgc ccgcagctgc gcgtcaaaat cttcggctga
     6481 cgggtccagc acgggcaact ccagacgcgt tgccacatgt tcacggcgcg ccggactggt
     6541 atccgccacc accacctgtg cgccatcggc tttagcgatt gccgccgcgc ccagaccgat
     6601 tggccccgcc ccgaccacca gcacctgctc gccgggagca atggctgcgc gacgcaccgc
     6661 atgagcgcta atagcgaaag gttcaatcaa tgcggccgcc tgcgggtcaa taccgtctgc
     6721 gggcaaaatg ttcgccaccg gcacgctcaa atactcacta aaaccgccat cctgatgcac
     6781 gccgatgact gaaatttttt cacagcaatt ggtacgaccg cttttacacg ctgggcattg
     6841 ctgacaggca acataaggga tcacagcaac ttgctgacca tttttaagat cagcaatatt
     6901 tttacccagc ccaacaatct ccccacatat ttcatggcct aaaacccgtg gataactaaa
     6961 aaatggttga tgtccacccc aggcatgaat atcggtaccg caaatcccga cagacttaat
     7021 ttttattaat gcttcattgt caccaggaat aggtatctcg cgttgtttcc agactaattc
     7081 tttcggctgc tggcaaatta aaacattcat cgtagacatg attcggctct ccattttttg
     7141 ttgccttaga tatcaatgaa aatgaaaaat ggcagcggaa cggaaaatct gttttgtgaa
     7201 aacacacgca taaaaatgtt ttaaatcggg ttttaatgga ctcacaaggg aaggtgcgaa
     7261 taagcgggga aattcttctc ggctgactca gtcatttcat ttcttcatgt
//
LOCUS       DADXDL010000153         7180 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.153, whole genome shotgun sequence.
ACCESSION   DADXDL010000153 DADXDL010000000
VERSION     DADXDL010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 7180)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7180)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7180
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.153"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..799)
                     /locus_tag="IRB70_004547"
     CDS             complement(<1..799)
                     /locus_tag="IRB70_004547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416491.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN/FAD transporter"
                     /protein_id="HBC0634378.1"
                     /translation="MLRHILTAKNLLSNPIFNFPNCLPFLSTVCCICRQFVGENLCSF
                     ADSPSLFEMWFHFLQLRSALNISSALRQVVHGTRWHAKRKSYKVLFWREITPLAVPIF
                     MENACVLLMGVLSTFLVSWLGKDAMAGVGLADSFNMVIMAFFAAIDLGTTVVVAFSLG
                     KRDRRRARVATRQSLVIMTLFAVLLATLIHHFGEQIIDFVAGDATTEVKALALTYLEL
                     TVLSYPAAAITLIGSGALRGAGNTKIPLLINGSLNILNIIISGILIYG"
     gene            804..879
                     /locus_tag="IRB70_004548"
     tRNA            804..879
                     /locus_tag="IRB70_004548"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:837..839,aa:Asn,seq:gtt)
     gene            complement(917..1867)
                     /gene="cbl"
                     /locus_tag="IRB70_004549"
     CDS             complement(917..1867)
                     /gene="cbl"
                     /locus_tag="IRB70_004549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH-type transcriptional regulator Cbl"
                     /protein_id="HBC0634379.1"
                     /translation="MNFQQLKIIREAARQDYNLTEVANMLFTSQSGVSRHIRELEDEL
                     GIEIFVRRGKRLLGMTEPGKALLVIAERILNEASNVRRLADLFTNDTSGVLTIATTHT
                     QARYSLPEVIKSFRELFPEVRLELIQGTPQEIATLLHNGEADIGIASERLSNDPQLVA
                     FPWFRWHHSLLVPLDHPLTQITPLTLESIAKWPLITYRQGITGRSRIDDAFARKGLLA
                     DIVLSAQDSDVIKTYVALGLGIGIVAEQSSGEQEEKNLIRLDTRHLFDANTVWLGLKR
                     GQLQRNYVWRFLELCNAGLSVEDIKRQVMENSEEEIDYQI"
     gene            complement(1969..2886)
                     /gene="nac"
                     /locus_tag="IRB70_004550"
     CDS             complement(1969..2886)
                     /gene="nac"
                     /locus_tag="IRB70_004550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitrogen assimilation transcriptional regulator
                     NAC"
                     /protein_id="HBC0634380.1"
                     /translation="MNFRRLKYFVKIVDIGSLTQAAEVLHIAQPALSQQVATLEGELN
                     QQLLIRTKRGVTPTDAGKILYTHARAILRQCEQAQLAVHNVGQALSGQVSIGFAPGTA
                     ASSITMPLLQAVRAEFPEIVIYLHENSGAVLNEKLINHQLDMAVIYEHSPVAGVSSQA
                     LLKEDLFLVGTQDCPGQSVDVNAIAQMNLFLPSDYSAVRLRVDEAFSLRRLTAKVIGE
                     IESIATLTAAIASGMGVAVLPESAARSLCGAVNGWMSRITTPSMSLSLSLNLPARANL
                     SPQAQAVKELLMSVMSSPVMEKRQWQLVS"
     gene            3212..3287
                     /locus_tag="IRB70_004551"
     tRNA            3212..3287
                     /locus_tag="IRB70_004551"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3245..3247,aa:Asn,seq:gtt)
     gene            complement(3343..4278)
                     /gene="ldtA"
                     /locus_tag="IRB70_004552"
     CDS             complement(3343..4278)
                     /gene="ldtA"
                     /locus_tag="IRB70_004552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310812.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase"
                     /protein_id="HBC0634381.1"
                     /translation="MMRRVNILCLFALLFASHTSLAVTYPLPPEGSRLVGQSLTVTVP
                     DHNTQPLETFAAQYGQGLSNMLEANPGADVFLPKSGSQLTIPQQLILPATVRKGIVVN
                     VAEMRLYYYPPDSNTVEVFPIGIGQAGRETPRNWVTTVERKQEAPTWTPTPNTRREYA
                     KRGESLPAFVPAGPDNPMGLYAIYIGRLYAIHGTNANFGIGLRVSQGCIRLRNDDIKY
                     LFDNVPVGTRVQIIDQPVKYTTEPDGSNWLEVHEPLSRNRAEYESDRKVPLPVTPSLR
                     AFINGQEVDVNRANAALQRRSGMPVQISSGSRQMF"
     gene            complement(4340..5419)
                     /gene="cobT"
                     /locus_tag="IRB70_004553"
     CDS             complement(4340..5419)
                     /gene="cobT"
                     /locus_tag="IRB70_004553"
                     /EC_number="2.4.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide--dimethylbenzimidazole
                     phosphoribosyltransferase"
                     /protein_id="HBC0634382.1"
                     /translation="MQTLADLLNTIPAIDPAAMSRAQRHIDGLLKPVGSLGRLEALAI
                     QLAGMPGLNGIPHVGKKAVLVMCADHGVWEEGVAISPKEVTAIQAENMTRGTTGVCVL
                     AAQAGANVHVVDVGIDSAEPIPGLINMRVARGSGNIASAPAMSRRQAEKLLLDVICYT
                     RELAKNGVTLFGVGELGMANTTPAAAIVSTITGRDPEEVVGIGANLPTDKLANKIDVV
                     RRAITLNQPNPQDGVDVLAKVGGFDLVGMAGVMLGAASCGLPVLLDGFLSYAAALAAC
                     QMSPAIKPYLIPSHLSAEKGARIALSHLGLEPYLNMEMRLGEGSGAALAMPIIEAACA
                     IYNNMGELAASNIVLPGNTTSDLNS"
     gene            complement(5431..6174)
                     /gene="cobS"
                     /locus_tag="IRB70_004554"
     CDS             complement(5431..6174)
                     /gene="cobS"
                     /locus_tag="IRB70_004554"
                     /EC_number="2.7.8.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosylcobinamide-GDP ribazoletransferase"
                     /protein_id="HBC0634383.1"
                     /translation="MSKLFWAMLSFITRLPVPRRWSQGLDFEHYSRGIITFPLIGLLL
                     GAISGLVFMVLQAWCGVPLAALFSVLVLALMTGGFHLDGLADTCDGVFSARSRDRMLE
                     IMRDSRLGTHGGLALIFVVLAKILVLSELALRGEPILASLAAACAVSRGTAALLMYRH
                     RYAREEGLGNVFIGKIDGRQTCVTLGLAAIFAAVLLPGMHGVAAMVVTMVAIFILGQL
                     LKRTLGGQTGDTLGAAIELGELVFLLALL"
     gene            complement(6171..6716)
                     /gene="cobU"
                     /locus_tag="IRB70_004555"
     CDS             complement(6171..6716)
                     /gene="cobU"
                     /locus_tag="IRB70_004555"
                     /EC_number="2.7.1.156"
                     /EC_number="2.7.7.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional adenosylcobinamide
                     kinase/adenosylcobinamide-phosphate guanylyltransferase"
                     /protein_id="HBC0634384.1"
                     /translation="MMILVTGGARSGKSRHAEALIGDSSQVLYIATSQILDDEMAARI
                     EHHRQGRPAHWRTVERWQHLDELIHADINPHEAVLLECVTTMVTNLLFDYSGDKDPDE
                     WDYQAMEQAINAEIQSLIAACQRCPAKVVLVTNEVGMGIVPESRLARHFRDIAGRVNQ
                     QLAAAANEVWLVVSGIGVKIK"
BASE COUNT         1949 a         1942 c         1576 g         1713 t
ORIGIN      
        1 ggccgtaaat caatatgccg ctaataataa tattaagaat attcaggcta ccgttaatca
       61 gtagcggtat tttcgtattc cctgcaccac gaagtgcccc gctaccaatc aaagtgatgg
      121 cagctgctgg ataactgagt accgtcagct ccagataagt caacgccagt gctttaactt
      181 ctgtcgtggc atcacccgcg acgaaatcaa taatttgctc gccaaaatga tgaataagcg
      241 ttgccaacag tacggcaaac aacgtcatga tcaccaatga ctgccgcgtc gccaccctcg
      301 ctcgtcgtcg atcccgctta ccgagactaa atgccacaac gacagtagta ccaagatcga
      361 tagcagcaaa aaaagccata atgaccatat tgaagctgtc cgccaatccc acgccggcca
      421 tcgcatcttt tcccagccag ctgaccagaa aagtgctcag aacccccatc aacaggacac
      481 aggcattctc catgaagata ggaacagcaa gcggggttat ctcgcgccag aacaacactt
      541 tgtagctctt gcgtttagcg tgccagcgag tgccgtgaac aacctggcgt aaagcagagg
      601 agatattcaa agccgacctt aattgcagaa agtgaaacca catttcaaat aatgagggag
      661 aatcagcaaa gctgcaaaga ttttcgccaa caaattgtct gcaaatgcaa caaactgttg
      721 atagaaacgg caaacagttg ggaaaattaa aaatcgggtt tgacaaaaga tttttcgccg
      781 ttaagatgtg cctcaacagc gattcctctg tagttcagtc ggtagaacgg cggactgtta
      841 atccgtatgt cactggttcg agtccagtca gaggagccaa atttctgaaa agcccgcttt
      901 tatagcgggc tttttgctat atctgataat caatttcctc ttcactgttt tccatcacct
      961 gccgcttgat atcctcaact gaaagccctg cattacaaag ttccagaaag cgccagacat
     1021 agttacgctg aagttgtcct cgcttcagtc ccaaccagac agtattagca tcaaaaagat
     1081 gccgcgtatc caggcggatt aaattctttt cctcttgttc accgctggat tgttcggcaa
     1141 ctattccgat cccaagccca agagcaacat aggttttaat gacatcagaa tcctgcgcac
     1201 ttaatacaat atctgccagc aaacctttgc gggcaaatgc gtcatcaata cgtgagcgcc
     1261 ccgtaatccc ctgtcggtaa gtgattaacg gccacttcgc tattgattcc agcgtcaatg
     1321 gtgtaatttg cgtcaaggga tgatcgagtg gaacaagcaa actatggtgc caacgaaacc
     1381 acgggaaggc gacgagctgc gggtcattac tcaaacgctc gctggcgata ccaatatcag
     1441 cttcaccatt atgcaacaac gtcgcaattt cctgtggcgt cccctggatt agctcgagcc
     1501 gaacctccgg gaaaagttcg cgaaaagatt taatgacctc tggcaaacta taacgtgcct
     1561 gagtatgcgt cgttgcaata gtgagaacgc cagacgtatc gttggtaaac aggtctgcaa
     1621 gccgacgaac attactggct tcattcagaa tacgttctgc aatgaccagt aatgctttgc
     1681 ccggttcagt catgcccagc agtcgcttac ctcgtcgaac aaatatttcg atgccaagtt
     1741 catcctccag ttcccgaata tgacggctga cgccggactg tgaggtaaaa agcatattcg
     1801 caacctctgt caggttgtaa tcctgacgtg cagcctcgcg gattatcttt agttgttgga
     1861 aattcacggt aaactccggg cagttcagat tttccgttat tgttaaagtc taatgcccgg
     1921 cataacaaat aataaaaacc cgcatcttat tccatcccga tataacgctt agctcaccaa
     1981 ttgccactgc cttttttcca tcactggaga actcatcact gacattaaca actctttcac
     2041 tgcctgtgcc tgtggcgata agttcgctct ggcgggtaaa tttaatgaca aagagagact
     2101 catggaaggc gtggtaatgc gtgacatcca cccatttact gcgccacata acgaacgcgc
     2161 ggccgattcg ggtaatactg caacgcccat gccgctggca atcgctgcgg taagcgtggc
     2221 aatagactca atttcaccaa tgacttttgc cgtgagccgc cgtagggaaa aagcctcatc
     2281 aacacgaagt ctaacagcac tgtaatcact ggggagaaag aggttcattt gcgcaatagc
     2341 attaacatca acgctttgcc ccgggcaatc ttgagttcct accaggaaaa gatcttcttt
     2401 cagcaaagcc tgactggata ccccagccac aggggaatgc tcataaatca ccgccatatc
     2461 gagttggtga tttatcagtt tttcgttaag cactgcaccg ctattttcat gaagatagat
     2521 aacgatctcc gggaattcag cgcgaaccgc ctgtaataag ggcatggtga tagatgacgc
     2581 agcggttcct ggcgcaaagc caatcgagac ttgccccgat aatgcctgac caacgttatg
     2641 caccgccagt tgggcctgct cacactgacg taaaatggcc cgcgcatggg tatagagaat
     2701 ttttccggcg tctgttggcg taacgccccg ttttgtgcga atcaaaagtt gttgatttaa
     2761 ctcaccttcc agtgtggcaa cctgctggct gagcgctggt tgtgcgatat gcaatacttc
     2821 agcagcctga gtcaggctac caatatctac aatttttacg aagtatttca ggcgtctgaa
     2881 gttcatgttg cctccggttt ttgagaatcg gcccaagtgc cgccattact tacaaccaga
     2941 ctgcaagatg cttgccagtt ttattttggc gttgatgtac aagctaacca actgtcaaat
     3001 aagagattat gatagattcg tcattggctc ttttcaccag cagtcgcgtt cccctgccct
     3061 ataaaaggag ggtatgcacc acgatggttc attaccaata agattgaaat ctcatcactt
     3121 tgttgaaatt ggcagcaaac aaacaaaaaa atgcatttca ccctttgaca tcaccatgca
     3181 ctgccattaa tatgcgcccc gttcacacga ttcctctgta gttcagtcgg tagaacggcg
     3241 gactgttaat ccgtatgtca ctggttcgag tccagtcaga ggagccaaat tcaaaaaagc
     3301 ctgctttcta gcaggctttt tgctttctaa ttaccaacgc tcttaaaaca tctgtcttga
     3361 accagaacta atttgcacag gcattcccga tcgacgttgc aacgcagcat ttgcgcgatt
     3421 cacatcaact tcttgcccgt tgataaacgc ccgcaaagat ggggttaccg gcaatggcac
     3481 ttttcggtca gactcatatt ctgcacgatt gcgcgacagc ggctcatgaa cttccagcca
     3541 gttcgagcca tctggttcag tggtgtattt tactggctgg tcgataattt gcacacgcgt
     3601 tccaacagga acattatcaa acagatattt gatatcgtca ttgcgcagac gaatacagcc
     3661 ctgacttacc cgaagtccaa taccaaaatt ggcattggta ccgtggatgg catacaacct
     3721 gccaatataa atcgcgtaca gccccatggg attatcgggc cccgcaggaa caaatgcggg
     3781 caaactctcc cctcgtttcg catattcgcg ccgagtgttc ggcgttggcg tccaggttgg
     3841 agcttcttgt ttacgttcaa cggtagtcac ccagttacgc ggggtttctc gcccagcctg
     3901 gccgatacca ataggaaaga cttccacagt attactgtct ggcgggtagt aataaagacg
     3961 catctcagcg acgttaacca caatcccctt acgaacagtg gcgggcaaaa tcagttgctg
     4021 cggaatggtg agttgcgagc cagacttcgg caagaaaaca tcagcgcccg gattcgcttc
     4081 cagcatgtta cttaaccctt gcccgtattg tgcggcaaaa gtctccagcg gctgggtatt
     4141 gtgatcagga acagttacag taagcgactg ccccaccaaa cggctaccct ctggaggtaa
     4201 tggataagtt accgccaggc tagtatggct ggcaaaaagc agagcaaata agcaaagaat
     4261 atttacacga cgcatcatgt ccctttccta tgtcgcgaaa gctatccgtt aagtatagct
     4321 tttatcagac ttttcgtttt taactgttca aatcagaagt cgtattcccc ggtagaacaa
     4381 tattactggc agcaagttcg cccatgttgt tatatatcgc acaggcagct tcgatgatgg
     4441 gcatcgccag agctgcgcca ctcccctcac ctaaacgcat ctccatattg agataaggct
     4501 ccagccccaa atgcgacagc gctatacgcg cccctttttc tgccgacagg tgagaaggaa
     4561 tgagatacgg tttgattgca ggagacatct ggcaggctgc gagcgcagca gcataagaaa
     4621 gaaatccatc cagcaacacg ggtaaaccgc aggaagcagc gcctaacatc acgccagcca
     4681 ttccgaccaa atcaaatccc cccacttttg ccagaacatc aacgccatcc tgcggatttg
     4741 gttgattcaa cgtaatcgcc cggcgcacaa catcaatttt attagccagt ttatctgtcg
     4801 gcaggtttgc gccaatccca accacttctt caggatcccg gccagtgatt gtgctgacta
     4861 ttgccgctgc cggtgtcgtg tttgccatcc ccagttcacc tacaccaaac agcgtgacac
     4921 cgttttttgc cagctcccgc gtataacata tgacgtccaa aagcaacttt tcagcctgac
     4981 ggcgactcat tgccggagct gaagcaatat tgccgctacc tcgtgcgaca cgcatgttga
     5041 taagcccggg gataggctca gcactatcaa taccaacatc aactacgtgg acgttagcgc
     5101 ccgcttgtgc tgccagcaca cacacgccgg ttgttccgcg ggtcatattt tcagcctgaa
     5161 tggctgtcac ttcttttggg gaaatagcga ccccttcctc ccagacgccg tgatcggcac
     5221 acataaccag taccgctttt ttgcccacat gcggtatgcc attcaacccc ggcattcccg
     5281 ccagttgtat ggcaagcgcc tccagccttc ccaggctacc aacaggtttg agtaacccgt
     5341 caatatgccg ttgtgcacgc gacatagcgg caggatcgat agcagggatc gtattcagta
     5401 aatcggcaag tgtttgcatg tcacgtctct ttatagcagt gccagcagga agaccagttc
     5461 accaagctct atagcagctc ccagcgtatc gccggtttgc ccgcccagcg tacgtttgag
     5521 aagctgaccg aggatgaaaa tcgccaccat cgtcaccacc atagcagcca caccatgcat
     5581 acccggcaat aatacggcag caaaaatagc ggctaagccg agtgtgacgc aggtttgtcg
     5641 cccatcaatt ttgccaatga acacattgcc aagcccttct tcccgggcat aacgatgacg
     5701 atacatcaat aatgcggcag tcccgcggct gaccgcacat gctgccgcca gcgatgcaag
     5761 gatcggttcg ccacgcagag ccaactcgct taataccaga atctttgcca gtacaacaaa
     5821 aatcaatgcc agaccgccat gggtgcctaa acggctatca cgcatgattt ccaacatgcg
     5881 atcgcggcta cgtgcagaaa atacgccatc acaggtatcg gcgaggccgt ccagatggaa
     5941 tcccccggtc atcagcgcca gcacaagtac gctaaacagt gccgccagtg gtacgccaca
     6001 ccatgcctgc agcaccatga agaccagccc gctaatcgcg ccaagcaata atccaattaa
     6061 aggaaaagta ataataccgc gagaataatg ctcgaaatcc agtccctggg accagcgacg
     6121 cggtacaggc agacgcgtaa taaatgagag catcgcccaa aataatttac tcatttgatt
     6181 tttactccaa tacccgaaac caccagccat acttcatttg ccgcagcggc cagctgctga
     6241 tttacccgcc cggcaatatc acgaaaatgt cgtgccagac gactctccgg cacaatcccc
     6301 attcccactt cgttagtcac taatacaacc tttgcggggc aacgttggca ggcagcaatc
     6361 aacgactgaa tctcagcatt aatcgcctgt tccatcgcct gataatccca ttcatcaggg
     6421 tctttatcgc cgctataatc aaacaacaga ttagtcacca ttgtggtaac gcattccagc
     6481 aacacagctt catgcgggtt aatgtctgca tgaattaatt catcaagatg ttgccaacgc
     6541 tccaccgtgc gccagtgcgc cggacggcct tgccgatgat gttctatccg tgcagccatc
     6601 tcgtcatcaa ggatttgcga ggtagcgata tacagaacct gtgaagagtc cccaataagc
     6661 gcctctgcgt ggcgactctt cccgctccgt gcgccccccg tcaccaaaat catcataccg
     6721 actcctgatt caaatgtatg atggtattca ttgaacagaa caatggatcc cccaccgttg
     6781 ctgaccgcaa aacatttacg cgattaatac tgcgcgtaat ataattaaaa atccagcatt
     6841 ctcaatccat tacgaaataa gatggcatta cggaatagcc agactttctc gtgttaacgt
     6901 ccgacaaaat gcgtcattga cagcggtttc tgtggattga cacatttcat tcagataatg
     6961 aattaatgct actgccggac caaccagcaa acgggcattg tgttctgaaa tccaggctat
     7021 tgattcaacg tcagcgacag atctgcgctg taaaagaact tgtaaaacaa cgcaatagaa
     7081 ttatccggaa tggtggcgac tatgcactag aacaccacaa tttcgctctc tcggtaaggc
     7141 actgtcacag cattcaacag aatgtgactt gccagattta
//
LOCUS       DADXDL010000154         6737 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.154, whole genome shotgun sequence.
ACCESSION   DADXDL010000154 DADXDL010000000
VERSION     DADXDL010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6737)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6737)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6737
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.154"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            137..913
                     /gene="exuR"
                     /locus_tag="IRB70_004556"
     CDS             137..913
                     /gene="exuR"
                     /locus_tag="IRB70_004556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator ExuR"
                     /protein_id="HBC0634385.1"
                     /translation="MEITEPRRLYQQLAADLKERIEQGVYLVGDKLPAERFIADEKNV
                     SRTVVREAIIMLEVEGYVEVRKGSGIHVVSNQPRHQQSADNNMEFANYGPFELLQARQ
                     LIESNIAEFAATQVTKQDIMKLMAIQEQARGEQCFRDSEWDLQFHIQVALATQNSALA
                     AIVEKMWTQRSHNPYWKKLHEHIDARTVDNWCDDHDQILKALIRKDPHAAKLAMWQHL
                     ENTKIMLFNETSDDFEFNADRYLFAENPVVHLDTATSGSK"
     gene            1258..1920
                     /locus_tag="IRB70_004557"
     CDS             1258..1920
                     /locus_tag="IRB70_004557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DedA family protein"
                     /protein_id="HBC0634386.1"
                     /translation="MELLTQLLQALWAQDFETLANPSMIGMLYFVLFVILFLENGLLP
                     AAFLPGDSLLVLVGVLIAKGAMGYPQTILLLTVAASLGCWVSYIQGRWLGNTRTVQNW
                     LSHLPAHYHQRAHHLFHKHGLSALLIGRFIAFVRTLLPTIAGLSGLNNARFQFFNWMS
                     GLLWVLILTTLGYMLGKTPVFLKYEDQLMSCLMLLPVVLLVFGLAGSLVVLWKKKYGN
                     RG"
     gene            1924..2307
                     /gene="mzrA"
                     /locus_tag="IRB70_004558"
     CDS             1924..2307
                     /gene="mzrA"
                     /locus_tag="IRB70_004558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EnvZ/OmpR regulon moderator MzrA"
                     /protein_id="HBC0634387.1"
                     /translation="MQIPRMSLRQLAWSGAVLLLVSTLLLAWSAVRQQESTLAIRAVH
                     QGTTMPDGFSIWHHLDAHGIPFKSITPKNDTLLITFDSSDQSAAAKAVLDRTLPHGYI
                     IAQQDNNSQAMQWLTRLRDNSHRFG"
     gene            2454..2822
                     /locus_tag="IRB70_004559"
     CDS             2454..2822
                     /locus_tag="IRB70_004559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417568.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1090 domain-containing protein"
                     /protein_id="HBC0634388.1"
                     /translation="MKYRIALAVSLFALSAGSYATTLCQEKEQNILKEISYAEKHQNQ
                     NRIDGLNKALSEVRANCSDSQLRADHQKKIAKQKDEVAERQQDLAEAKQKGDADKIAK
                     RERKLAEAQEELKKLEARDY"
     gene            2860..3165
                     /locus_tag="IRB70_004560"
     CDS             2860..3165
                     /locus_tag="IRB70_004560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF883 domain-containing protein"
                     /protein_id="HBC0634389.1"
                     /translation="MSKEHTTEHLRAELKSLSDTLEEVLSSSGEKSKEELSKIRSKAE
                     QALKQSRYRLGETGDAIAKQTRVAAARADEYVRENPWTGVGIGAAIGVVLGVLLSRR"
     gene            3168..3572
                     /locus_tag="IRB70_004561"
     CDS             3168..3572
                     /locus_tag="IRB70_004561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBC0634390.1"
                     /translation="MADTHHAQGPGKSVLGIGQRIVSIMVEMVETRLRLAVVELEEEK
                     ANLFQLLLMLGLTMLFAAFGLMSLMVLIIWAVDPQYRLNAMIATTVVLLLLALIGGIW
                     TLRKSRKSTLLRHTRHELANDRQLLEEESREQ"
     gene            3562..3861
                     /locus_tag="IRB70_004562"
     CDS             3562..3861
                     /locus_tag="IRB70_004562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqjK-like family protein"
                     /protein_id="HBC0634391.1"
                     /translation="MSSKVEHERRKAQLLSQIQQQRLDLSATRREWLEATGAYDRRWN
                     MLLSLRSWALVGSSVMAIWTIRHPNMLVRWARRGFGVWSAWRLVKTTLKQQQLRG"
     gene            4047..4439
                     /locus_tag="IRB70_004563"
     CDS             4047..4439
                     /locus_tag="IRB70_004563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008503138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DoxX family protein"
                     /protein_id="HBC0634392.1"
                     /translation="MKKLEDVGVLVARILMPILFITAGWGKITGYAGTQQYMEAMGVP
                     GFMLPLVILLEFGGGLAILFGFLTRTTALFTAGFTLLTAFLFHSNFAEGVNSLMFMKN
                     LTISGGFLLLAITGPGAYSIDRLLNKKW"
     gene            4509..5495
                     /gene="yqjG"
                     /locus_tag="IRB70_004564"
     CDS             4509..5495
                     /gene="yqjG"
                     /locus_tag="IRB70_004564"
                     /EC_number="1.8.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708909.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathionyl-hydroquinone reductase YqjG"
                     /protein_id="HBC0634393.1"
                     /translation="MGQLIDGVWHDTWYDTKSTGGKFQRSASAFRNWLTADGAPGPTG
                     TGGFIAEKDRYHLYVSLACPWAHRTLIMRKLKGLEPFISVSVVNPLMLENGWTFDDSF
                     PGATGDTLYQHEFLYQLYLHADPHYSGRVTVPVLWDKKNHTIVSNESAEIIRMFNTAF
                     DALGAKAGDYYPPALQTKIDELNGWIYDTVNNGVYKAGFATSQQAYDEAVAKVFESLA
                     RLEQILGQHRYLTGNQLTEADIRLWTTLVRFDPVYVTHFKCDKHRISDYLNLYGFLRD
                     IYQMPGIAETVNFDHIRNHYFRSHKTINPTGIISIGPWQDLDEPHGRDVRFG"
     gene            5778..6143
                     /locus_tag="IRB70_004565"
     CDS             5778..6143
                     /locus_tag="IRB70_004565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HBC0634394.1"
                     /translation="MDWYLKVLKNYVGFRGRARRKEYWMFILVNIIFTFVLGLLDKML
                     GWQRAGGEGILTTIYGILVFLPWWAVQFRRLHDTDRSAWWALLFLIPFIGWLIIIVFN
                     CQAGTPGENRFGPDPKLEP"
     gene            6385..>6737
                     /locus_tag="IRB70_004566"
     CDS             6385..>6737
                     /locus_tag="IRB70_004566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF805 domain-containing protein"
                     /protein_id="HBC0634395.1"
                     /translation="MQWYLAVLKNYVGFSGRARRKEYWMFTLINAIVGAIINVIQLIL
                     GLEFPFLSLIYLAATIIPVIALCVRRLHDTDRSGAWALLYLVPVIGWLVLFVFACLEG
                     NSGSNRYGNDPKFSS"
BASE COUNT         1706 a         1619 c         1654 g         1758 t
ORIGIN      
        1 attttaggaa tatattaata ttcataacat caataaataa tattatttca atcatgcgat
       61 ttatatttta acaatggcat acgcatgcat aaagtggtat gataactttg tccgcattcc
      121 actcctggag acgcatatgg aaatcactga accacgccgt ttgtatcaac aacttgccgc
      181 tgatctgaaa gagcgcatcg aacagggcgt ctatctggtg ggtgataaac tgcctgccga
      241 acgctttatt gccgatgaaa aaaacgtcag ccgcaccgtg gttcgtgaag ccatcatcat
      301 gctggaagtt gaaggctatg tcgaagtgcg taaaggttca ggtattcatg tggtttccaa
      361 ccagccgcgc catcagcaat cggctgacaa taatatggag tttgccaatt acggtccgtt
      421 tgagctactg caagcccgcc agctcatcga aagtaatatt gccgagttcg cggcaactca
      481 ggtcacaaaa caggacatca tgaaattgat ggccatccag gagcaggcac gcggcgaaca
      541 atgcttccgt gattccgagt gggatttgca gttccatatt caggtagccc tggcgacgca
      601 gaactccgcc ctggcggcta tcgttgaaaa aatgtggacc cagcgtagtc ataacccgta
      661 ctggaaaaaa ctgcacgaac acattgatgc ccgtaccgtc gataactggt gtgatgacca
      721 cgatcaaatc ctcaaagcgc tgattcgcaa agatcctcat gctgctaagc tggcaatgtg
      781 gcagcacctg gaaaacacca agatcatgtt atttaacgaa accagcgacg atttcgagtt
      841 caatgccgac cgctatctgt tcgccgaaaa cccggtggtg catctcgata cagccaccag
      901 cggcagtaaa tgaaattcct gtccgacagg cgctacagtg cgcctgtttg tctcgtcggt
      961 aagcgaaaag tataaagtgt cagcctgtgt aaatcctctc gcctccctcc cctgcattca
     1021 gcaaaatcag actccacgga catgtaattt tgataacgaa caacgttgac ctttgttaca
     1081 attagattca atttgaattt atgcttttga atgctttctt atctcacgat ttaacaggga
     1141 atagttcagg ctgtgttgat gtatcaaacc cgcaaaacat accaaaacag caataacatt
     1201 gcggtagtgc atcatttaaa accagcgtgg cgttaaccga ttcaccagga ataatgaatg
     1261 gaacttttga cccaattgct gcaagccctg tgggcgcagg attttgaaac cctggccaat
     1321 ccgtcgatga ttggcatgtt gtattttgtc ttgtttgtca ttttgttcct tgaaaacggc
     1381 ttgcttccgg cggccttttt accgggcgac agtttactgg tactggtcgg cgtattgatt
     1441 gcgaaaggcg cgatgggcta tccgcaaacg attctgctgc tgaccgttgc cgccagcctc
     1501 ggttgctggg tcagctatat tcaggggcga tggctgggca atacccgcac cgtacaaaac
     1561 tggctatctc atttacccgc gcattatcat caacgcgcac accatctttt tcataaacac
     1621 ggtttatcgg cgctgttaat tggtcgcttt attgcgtttg tcagaacact gctgccgacg
     1681 attgccgggt tatcagggct gaataacgcg cgctttcagt tcttcaactg gatgagtggt
     1741 ctgctgtggg tattgatcct gacaactctg ggttacatgc tcggcaaaac gccggtattt
     1801 ttaaagtacg aggaccagct gatgtcatgc ctgatgctgc tcccggtggt gctgctggtg
     1861 tttggcctgg caggttctct ggttgtgtta tggaaaaaga aatatggaaa tcgggggtaa
     1921 gggatgcaaa tacctcgcat gtcacttcgc cagctagcct ggtccggcgc tgttttactt
     1981 ctggtcagca cactattgct ggcctggtcc gcggttcgcc agcaagagtc tacgctggcg
     2041 attcgtgccg ttcatcaagg gacaacgatg ccagacggtt tttcgatctg gcatcacctt
     2101 gacgctcacg gcattccttt caaaagtatc acccccaaaa acgacactct gttaattacc
     2161 tttgactcca gcgaccagag cgccgccgca aaagcggtcc tcgacagaac attgccccat
     2221 ggctacatca ttgcgcagca ggacaataac agtcaggcta tgcagtggct gacccggttg
     2281 cgggataact ctcatcgctt cggataactt cctgttatct gaaacagatc actcactttg
     2341 gtgatttcac cgtaactgtc tatgattaat ggggcggtgg ttaacacgac cgcttcgttg
     2401 tctggacaat cgttcctttg taataggtcc gaatcacaat ggaaggttca agaatgaaat
     2461 accgcatcgc tttagctgtt tctctctttg ctcttagtgc cggtagttat gccactaccc
     2521 tgtgtcagga aaaggagcaa aatatcctta aggagatcag ctatgccgaa aaacaccaaa
     2581 accagaatcg tattgacggt ctgaataaag ccctgagtga agtccgggcc aactgttcag
     2641 atagccaact gcgtgccgat catcagaaga aaatcgcaaa gcagaaagat gaggtggcgg
     2701 aacgccagca agatttagcc gaggcgaagc aaaaaggcga tgcagataag attgccaaac
     2761 gcgaacggaa actggcagaa gcgcaggaag agctgaaaaa gctggaagcg cgcgactact
     2821 aactcacaat agtcactact tactcacctg gagaaaacta tgtcgaaaga acacactacg
     2881 gaacatctgc gtgctgagtt gaaatccctt tccgatacgc tggaagaggt gcttagctca
     2941 tctggcgaga agtcgaaaga agagttgagt aagattcgta gcaaagcgga gcaggcactg
     3001 aaacagagcc gttatcgcct gggtgaaacc ggtgatgcca tcgccaaaca aacccgtgtc
     3061 gcggcggcgc gtgccgatga gtatgtgcgt gaaaatccgt ggaccggcgt gggcattggc
     3121 gctgcaatcg gtgtagtgct cggcgttctg ctgtcgcgtc gttaattatg gcggacactc
     3181 atcacgcgca agggcccggt aaaagcgttc tgggcatcgg gcagcgaatt gtttccatca
     3241 tggttgaaat ggtggaaaca cgtctgcggc tggcggtggt ggagctggaa gaggaaaaag
     3301 cgaatctctt tcaactttta ctgatgctgg gcctgacgat gcttttcgct gcatttggtc
     3361 ttatgagcct gatggtgcta attatttggg cggttgatcc gcaatatcgc ctgaatgcga
     3421 tgattgccac caccgtggtg ttgctgctac tggcactgat tggcggtatc tggacgttac
     3481 gtaaatcgcg taaatccacc ttgctgcgcc atacacgcca tgagctggca aacgatcggc
     3541 agctgctcga ggaggagtcc cgtgagcagt aaagtcgaac atgaacgacg taaggcgcaa
     3601 ctgcttagcc agatccagca acaacggctg gatctttccg ccactcgtcg tgaatggctg
     3661 gaggcaacag gcgcttacga tcgtcgctgg aatatgctgt tgagtctgcg ctcctgggcg
     3721 ctggttggca gtagcgtgat ggctatctgg acgattcgcc atcctaatat gctggtccgc
     3781 tgggccagac gcggttttgg tgtatggagc gcctggcgtc tggttaaaac gaccctcaag
     3841 cagcaacagc ttcgcggtta acttccctct ggccggagcc attccggcct tatccctcaa
     3901 attttttgaa gatttttgac aattttcctt gctaacaatc acgcttcgcc acgtttatga
     3961 ttctctccat cgacagcaac gacgctaata gcgcgccctt gcacaaaaaa acaatcagca
     4021 gcctgagcgg cgcagtggag agtatgatga aaaaattaga agatgttggt gtactggtag
     4081 cgcgtatttt aatgccgatt ctgtttatta ccgcaggctg gggaaaaatt actggctacg
     4141 cgggtaccca acaatatatg gaagcaatgg gcgtccccgg ctttatgctg ccgctggtga
     4201 ttctgcttga gtttggtggt ggtctggcaa tcctgttcgg tttcctgaca cgtaccacag
     4261 ccctgtttac tgcgggcttt acgctgctga cggcattttt atttcacagc aactttgctg
     4321 aaggcgtcaa ctcgctgatg ttcatgaaaa acctgacgat ttctggcggg ttcctgctgc
     4381 tggcgattac cggtccgggc gcgtatagca tcgaccgcct gctgaataaa aagtggtaag
     4441 cacgcgctat acttaacaat aaaaaacgag gaggaagctc ctcgtttttg ctattggagg
     4501 agagaaaaat gggtcaactg attgacggcg tctggcatga cacctggtac gataccaaat
     4561 ccaccggcgg taaatttcaa cgttcagctt ccgcatttcg taactggctc actgccgatg
     4621 gcgcgccagg ccccactggc acaggcggtt ttatcgcaga gaaagatcgt tatcatctct
     4681 atgtttcact cgcctgcccg tgggcgcacc gcacgctgat catgcgtaag ctcaaaggac
     4741 tggaaccgtt tatttccgtt tccgtagtga acccgctgat gctggaaaac ggctggacct
     4801 ttgatgacag ttttccggga gcaaccggcg acacgctcta tcaacatgaa tttctgtatc
     4861 agctttatct ccacgccgat ccacactaca gcggacgagt tactgttccc gtgctgtggg
     4921 acaaaaaaaa ccacaccatc gtcagcaacg aatcagcaga aatcatacgc atgttcaata
     4981 ccgcgtttga tgcgctgggc gcgaaagcgg gtgattacta cccaccagcc ctgcaaacga
     5041 aaattgacga acttaacggc tggatttatg acactgttaa caacggcgtg tataaagctg
     5101 gttttgccac cagccagcaa gcttacgacg aggcggtggc gaaagtgttt gaatcgctgg
     5161 cgcgactgga acagatttta ggtcagcacc gttacctgac cggcaaccag ctaaccgaag
     5221 ccgatattcg cctgtggacc acgctggtgc gttttgatcc agtgtatgtg acccacttca
     5281 agtgtgataa gcaccgcatc agcgattacc tgaatctgta tggcttcctg cgcgatatct
     5341 accagatgcc gggaattgcc gaaacagtca atttcgatca catccgtaat cattacttcc
     5401 gcagccataa gaccatcaac cctacgggga ttatttcaat tggtccgtgg caggatctcg
     5461 atgaaccgca tggacgagat gttcgcttcg gttaaaaaaa ggcaccttac gaggtgcctc
     5521 tgataattag ctaagtgcgt gttgttcatg tcggatgcgg cgtaaacgcc ttatcaaacc
     5581 tacaaaacat ttatattcaa tatgttgcaa tgaccgcgca ggccagataa gcgtagcgca
     5641 tctggcaatt ttgcgcttgc ccttatcctt cacagcgcct tattaattca tcgagataat
     5701 atttactgcc atttcattca cgtctattct taatttgctg ctttaaaaac aagtgattga
     5761 gcaaaattga ggcaaaaatg gactggtatc tgaaagtact aaaaaattat gtcggtttcc
     5821 ggggtcgtgc gcggcgcaaa gagtactgga tgtttattct ggtcaacatc atctttacgt
     5881 tcgtgctggg gctactggat aaaatgttag gctggcaacg tgccggtggc gaaggcatcc
     5941 tgacgacaat ctacggtatt ctggtgtttt taccatggtg ggcagttcag ttccgccgcc
     6001 tgcacgacac cgaccgctcg gcgtggtggg cactgctgtt cttaatcccg tttatcggct
     6061 ggcttattat catcgtcttt aactgccagg cgggtacgcc aggcgaaaac cgctttggac
     6121 ctgatccaaa actggaacct taaaacaaat ctcctcgccg gatgtctgac tcatccggct
     6181 tttatcatca tgttgatgaa tgaataattt actaatgttt atttaaaata tttcaatatc
     6241 gttatataaa ttacctataa aaaataacca tgtatttatc ttaaatatca aaacctttat
     6301 aacatccgaa aaagaaagat acgaatagca tttacacaat acccggaata gactttcgtc
     6361 acttttaatt aaagggatgt ttttatgcag tggtatttag ccgtattaaa aaattatgtt
     6421 ggtttctctg gtcgcgcacg tcgtaaagag tactggatgt ttactctgat taacgccatc
     6481 gtcggcgcta ttatcaatgt cattcaattg attttaggtt tagagtttcc attcctttct
     6541 ctcatttacc tggcagcaac aatcattccg gtcattgctc tgtgcgttcg tcgtctgcac
     6601 gatactgacc gttcaggtgc gtgggcgctt ctctatctgg taccggtcat tggctggtta
     6661 gttctgtttg tatttgcctg tttagaaggc aattctggca gcaatcgtta cggaaacgat
     6721 ccgaagttta gttcaaa
//
LOCUS       DADXDL010000155         6733 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.155, whole genome shotgun sequence.
ACCESSION   DADXDL010000155 DADXDL010000000
VERSION     DADXDL010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6733)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6733)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6733
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.155"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..221
                     /locus_tag="IRB70_004567"
     CDS             <1..221
                     /locus_tag="IRB70_004567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634396.1"
                     /translation="YDNAMAESINGLYKAEVIHRKSWKKRAEVELATLTWVDWYNNRR
                     LLGRLRHTPPAEAEKAYYASIGNDELAT"
     gene            243..476
                     /locus_tag="IRB70_004568"
                     /pseudo
     CDS             243..476
                     /locus_tag="IRB70_004568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013141603.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            553..861
                     /locus_tag="IRB70_004569"
                     /pseudo
     CDS             553..861
                     /locus_tag="IRB70_004569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000244358.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
     gene            complement(920..2230)
                     /locus_tag="IRB70_004570"
     CDS             complement(920..2230)
                     /locus_tag="IRB70_004570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBC0634397.1"
                     /translation="MFKPLTALTVGLSLALSGAALAKEKIDFMFPAPVDGKLTMEMTR
                     VIKQFNDSQQDVEVRGIFTGNYDTTKIKAESAQKAGQPPALVIMSANFTTDLALKDEI
                     LPMDELFKYGDQKAGNFLQTEFWPAMHKNAQVMGTTYAIPFHNSTPLLYYNKTMFDRA
                     GIQQPPQTWAELLADAKKLTDESTGQWGIMLPSTNDDFGGWIFSALVRANGGKYFNED
                     YPGEVYYNSPTTIGALRFWQDLIYKDKVMPSGVLNSKQISAAFFSGKLGMAMLSTGAL
                     GFMRENSKDFELGVAMLPAKEQRAVPIGGASLVSFKGISEAQKKAAYRFLTYLVSPEV
                     NGAWSRFTGYFSPRKASYDTPEMKAYLQQDPRAAIALEQLKYAHPWYSTWETVAVRKA
                     MENQLAAVVNDAKVRPEAAVQAAQKEADALMKPYVDKTALSEVK"
     gene            complement(2223..3296)
                     /locus_tag="IRB70_004571"
     CDS             complement(2223..3296)
                     /locus_tag="IRB70_004571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBC0634398.1"
                     /translation="MLSLQNISKRFDGKPALSALSLDIHEGEFVVLVGPSGCGKSTLL
                     RLLAGLEPVSEGQIWLHDENITATTPRDRNFAMIFQNYALFPHLSVRDNITFGMKVRK
                     EEKSSWQPRVDKVAQMLQLEALLDCKPAKLSGGQRQRVAMARAIVRNPRLFLMDEPLC
                     NLDARLRSEVRDSIMALHQQLKTSTIYVTHDQTEAMSMADRIVVMNGGHVQQVGHPEY
                     LYANPANLFVAGFIGSPAMNLLSLPCANGEVLLGEQRHPLPPRHRDQTRVWLGVRPEH
                     ITDHVEEDHLRLPATVLQRELMGADYLLHVSTPIGTLRFSRRNRGKVPEKDESLPIGF
                     SPADVHLFHAETQHNLQMETDHV"
     gene            complement(3302..4126)
                     /locus_tag="IRB70_004572"
     CDS             complement(3302..4126)
                     /locus_tag="IRB70_004572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphodiesterase"
                     /protein_id="HBC0634399.1"
                     /translation="MLLAHISDTHFRSRGEKLYGFIDVNAANADVVSQLNALRERPDA
                     VVVSGDIVNCGRPEEYQVARQILGSLNYPLYLIPGNHDDKAHFLEHLHPLCPQLGNDP
                     QNMRYVVDDFATRLLFIDSSHAGTSKGWLTDETIGWLEAQLFEGGDKPATIFMHHPPL
                     PLGNAQMDPIACENGHRLLELVERFPSLTRIFCGHNHSLTITQYLQALISTIPGTVHQ
                     VPYCHEDTRSYYDLSPASCLMHRQVGEQWVSYQHSLAHHAGPWLYDENISCPTEER"
     gene            complement(4137..5024)
                     /locus_tag="IRB70_004573"
     CDS             complement(4137..5024)
                     /locus_tag="IRB70_004573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBC0634400.1"
                     /translation="MSADISPLLVHTPAAARPLWLRLRRSSPFTLTVLMCCLALLWVS
                     PFIWMLTTSFSATTFGDDMASLLPRLPLTLDNFRDAWNSADWLSLYANTIIFTFGTFF
                     VQLLTITTAGYVFACHEFRGKQTLFLLFLVQLMIMPVVMMVPNMLTLKTFGLLNTLIG
                     VMMPYFTSAFGVFLMRKAFLAIPKELEEAALMEGCSWWQVLFRVLLPMSWPSVLAFAT
                     VSITYHWNEYLWPLMMLNDPDKQVLTVGLVSFAMGAESGGQWGTIGAGTLMVCLPLML
                     AFILFQKQFLRSFGFSGIK"
     gene            complement(5014..5892)
                     /locus_tag="IRB70_004574"
     CDS             complement(5014..5892)
                     /locus_tag="IRB70_004574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBC0634401.1"
                     /translation="MCVTMRKTWLPWLILSPSLLFLLLFTWFPLGRSVYDSLFDTRMA
                     NAQYVGLDNFARLFADNVFWQSLGNNLLYILLTVMPGVTLALLLAVALSENHRVNRWL
                     RTAFFFPMIIPMVSAAALWLFIFMPGLGLLDHYLAKLFGPMNNNWLGRSNSALLALAL
                     IGVWKFAGYYMLFFLAGLQSIPASTREAALMEGATRTQVFFKVTLPLLRPTLSFVITT
                     ALIYSITQIDHVAVMTRGGPDNATTVLLYYIQNLTWDTHDLGKASAATFLTLAGLFAF
                     SLINLKLLEKGAHYER"
     gene            complement(6023..6463)
                     /locus_tag="IRB70_004575"
                     /pseudo
     CDS             complement(6023..6463)
                     /locus_tag="IRB70_004575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005224837.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding dehydrogenase"
     gene            6437..6631
                     /locus_tag="IRB70_004576"
     CDS             6437..6631
                     /locus_tag="IRB70_004576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000796505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634402.1"
                     /translation="MAEAADADHPLPVGTQLIGEAAAARLAEKNVLLTPSGRASALAF
                     MMTLRADRRYKDAQPLPLVT"
BASE COUNT         1437 a         1869 c         2068 g         1359 t
ORIGIN      
        1 cgtatgacaa cgcgatggcg gagagcatta atggtcttta caaagcggag gtaatacacc
       61 gtaagagctg gaaaaaacgt gcagaagtgg aactggccac actcacgtgg gtggactggt
      121 ataacaatcg acgattgctg ggaaggctga ggcatactcc tccggcagaa gcagaaaaag
      181 cgtattatgc ttccatcgga aatgatgagc tggcaacctg agttcacaga taaaacactc
      241 tccaggaaaa ccggggcggt tcactggcgc tcaatattat tgttctgtgg aacactattt
      301 acatggatgc agcaattcag catctcaggc gtgaggagta cccggtcctg gattcagacg
      361 ttgagaaact gtcaccatta cagtgcgggc atattaatat gcaagggcgc tattcattta
      421 tagtgccgga atcagtcagt aagggtgagc tgagggcgtt caatgaagat gtatgattta
      481 ttgattaata gataattggc tattttaatt aacctcttaa cggcgttact gttccattgc
      541 tccccaaacc cctttatagc ggtacgggtg ctgggcctgc ggcagggagg tatcagtgaa
      601 gaaacacaaa atgacagctg tgagaaaata ctggcgccga cagagtggaa attgctgtgg
      661 gttaagctgg aaggaaaacc gcttccgtca cagacgccga cactgaaatg ggcctgtctg
      721 aaactggcga aactggggcg atggtatgac agcaaacgca caggccgccc cggttgggta
      781 gttatgtggg atggctggtt cagacttcag gatatggttg agggttacct ggtgatgaag
      841 tctcttgatc aggagatctg atcaagagac agccctcagg gagagggcca ggatgagggt
      901 gacgatgacg ggtaacgcgt cacttcactt ccgacaacgc ggtcttatcc acatagggtt
      961 tcattagcgc gtcagcttcc ttctgcgccg cctgtaccgc ggcttccggc cttactttgg
     1021 catcgttgac caccgccgcc agctggttct ccatcgcctt acgcacggcg acggtctccc
     1081 aggtggagta ccatggatgg gcgtacttca gttgctcaag cgcaatcgcc gcccgcggat
     1141 cctgctgcag ataggccttc atctctggcg tatcgtatga cgccttgcgc ggcgagaagt
     1201 agccggtgaa gcggctccat gcgccgttca cctcggggct caccagatag gtcaggaacc
     1261 gatacgctgc tttcttctgc gcctcgctga tgcctttaaa acttacgagg ctggcgccgc
     1321 cgatcggcac tgcgcgctgc tctttggctg gcagcatagc taccccaagc tcaaagtctt
     1381 tgctgttctc acgcataaag cccagcgcgc cggtgctgag catcgccatc ccgagcttgc
     1441 cggagaagaa cgcggcgctg atctgtttcg agttcagcac cccggacggc atcaccttgt
     1501 ctttgtagat cagatcctgc cagaagcgca gggcgccgat tgtggtcggc gagttgtaat
     1561 agacctcgcc cggatagtct tcgttaaagt attttccgcc gttggcgcgc accagcgccg
     1621 agaagatcca gccgccgaag tcgtcgttgg tcgacggcag catgatcccc cactggcctg
     1681 tgctctcgtc ggtcagcttt ttggcatcgg ccagcaactc ggcccaggtc tgcggcggct
     1741 gttggatccc ggcccgatcg aacatcgtct tgttgtagta gaggagcggc gtcgagttat
     1801 ggaacgggat cgcataggtg gtgcccatca cctgggcgtt cttatgcatc gcgggccaga
     1861 attccgtttg cagaaaattg ccggcctttt gatcgccata tttaaacagc tcatccatcg
     1921 gcaggatctc atccttcagc gccagatcgg tggtgaagtt ggcggacatg atcaccagcg
     1981 ccggtggctg gccggccttc tgcgccgatt cggctttgat cttggtggtg tcgtagttgc
     2041 cggtgaagat tccgcgcact tcgacatcct gctgcgagtc gttgaattgc ttaatgacgc
     2101 gggtcatctc catggtcagc ttgccgtcca ccggcgccgg gaacataaag tctattttct
     2161 ctttcgccag cgccgcgccg ctcagggcaa ggctgagccc aaccgtcagg gcggtgaggg
     2221 gtttaaacat gatctgtctc catctgtaaa ttatgctggg tctcagcatg aaaaagatgc
     2281 acatcggcag gcgagaagcc gatcggtagc gactcgtctt tctccggcac cttgccgcgg
     2341 ttgcggcggc taaagcgcag ggtgccgatc ggggtgctga cgtggagcag ataatcggct
     2401 cccatcagtt ctcgttgcag aacggtggcc ggcaggcgca gatggtcctc ctccacgtgg
     2461 tcggtaatat gttccgggcg aacgcccagc cagacgcggg tctgatcccg gtggcgcggc
     2521 ggcagcggat ggcgctgttc tcccaacagt acttcaccgt tggcgcaggg cagcgacagg
     2581 aggttcatcg ccggcgaacc gataaaccca gcgacgaaca ggttggccgg gttggcgtac
     2641 agatactccg ggtgcccgac ctgctgcacg tggccgccgt tcatcaccac gatgcggtcg
     2701 gccatcgaca tcgcctcggt ctgatcgtgg gtcacataga tggtgctggt tttcagctgc
     2761 tgatggaggg ccataatgct gtcgcgcact tcgctgcgca ggcgggcgtc gaggttgcag
     2821 agcggctcgt ccatcaggaa cagccgcgga ttacgcacaa tcgcccgggc catcgccacc
     2881 cgctggcgct ggccgccgga gagcttcgcc ggtttgcagt cgagcagcgc ctccagctgc
     2941 agcatctgcg ccactttatc cactcgcggc tgccagctgc ttttctcttc cttgcgcacc
     3001 ttcatgccga aggtgatgtt gtcgcgcacc gacagatgcg gaaacagggc atagttctgg
     3061 aagatcatcg cgaagttgcg atcgcgcggc gtggtggcgg tgatgttctc atcatgcagc
     3121 cagatttggc cttcgctgac cggttccagc ccggcgagca ggcgtagcag ggtgcttttc
     3181 ccgcagcccg acgggccgac cagcaccacg aattcgcctt cgtggatatc cagcgacagg
     3241 gcgctgagcg ccggtttgcc gtcgaaacgt ttactgatgt tttgcagact gagcatggca
     3301 gttagcgctc ttccgttggg caactgatgt tttcgtcgta cagccacggt ccggcgtggt
     3361 gggccagcga gtgctggtag ctcacccact gctcgccgac ctgacggtgc atcaggcacg
     3421 aggccgggga gagatcgtaa taggaccggg tatcttcgtg gcagtacggc acctgatgga
     3481 cggtgccagg aatggtggag atcagcgcct ggagatactg ggttatggtc aggctgtggt
     3541 tatggccgca gaagatgcgc gtcagcgacg gaaaacgctc caccaactcc agcagacggt
     3601 ggccattttc gcaggcaata ggatccatct gcgcattgcc cagcggcagc ggcgggtggt
     3661 gcataaagat cgttgccggt ttgtcgccgc cctcgaacag ctgggcttcc agccagccga
     3721 tggtctcgtc ggtcagccag ccttttgacg tgccggcatg actggagtcg ataaacagca
     3781 ggcgggtggc gaagtcatcc accacatagc gcatattttg cggatcgttg cccagctgcg
     3841 ggcacagcgg gtgaagatgt tcgagaaaat gggctttgtc gtcgtggttg ccggggatca
     3901 gatacagcgg atagttcagg ctgccgagga tctggcgggc cacctgatac tcctccgggc
     3961 ggccgcagtt gacgatatcc ccgctcacca ccaccgcgtc cgggcgctcg cgcagtgcgt
     4021 taagctggga gaccacgtcg gcgttggcgg cattgacgtc gataaagcca tacagcttct
     4081 cgccgcggct gcgaaaatgg gtatcggaaa tgtgtgctaa cagcatgaat cactccttat
     4141 ttgatcccgg agaagccgaa gctccgcagg aactgtttct gaaaaaggat aaacgccagc
     4201 atcagcggca ggcagaccat cagcgtcccg gcgccgatgg tgccccactg gccaccggat
     4261 tcggcgccca tggcgaaaga gaccagcccg acggtcagca cctgcttatc gggatcgttg
     4321 agcatcatca gcggccacag gtactcgttc cagtggtagg taatgctgac ggtagcgaag
     4381 gccagcaccg acggccagga catcggcagc agcacgcgga acagcacctg ccaccagctg
     4441 cagccctcca tcagcgccgc ctcctccagc tctttcggaa tggcgaggaa cgccttacgc
     4501 attaggaata cgccgaacgc cgaggtgaag tagggcatca tcaccccgat gagggtgttg
     4561 agcagaccga aggttttcag ggtcagcatg ttcggcacca tcatcactac cggcatgatc
     4621 atcagctgca ccaggaacag gagaaacagc gtctgcttgc cgcgaaactc gtgacaggca
     4681 aagacgtagc cggcggtggt gatggtcaac agctgcacga agaaggtgcc gaaggtgaag
     4741 ataattgtgt tggcgtacag gctcagccag tcggcgctgt tccaggcgtc gcggaagtta
     4801 tcgagagtca gcggcaggcg cggcagcagc gaggccatat cgtcgccgaa ggtagttgcg
     4861 ctgaatgagg tggtcagcat ccagataaac gggctgaccc acagcagcgc caggcagcac
     4921 attaatactg tgagcgtaaa gggcgacgag cgacgcaggc gcagccacag cggacgcgca
     4981 gcggcgggtg tgtggaccag cagcggcgag atgtcagcgc tcatagtggg ctcctttctc
     5041 cagcagtttc aggttaatca gcgagaaggc gaacagtccg gccagggtca ggaaggtggc
     5101 tgcggaggct ttaccaaggt cgtgggtatc ccaggtgaga ttctggatgt aatagagcag
     5161 cacggtggtg gcgttatccg gcccgccgcg agtcatcacc gccacgtggt caatctgggt
     5221 gatggagtag atcagcgcgg tggtgatcac aaagctcagc gtcgggcgca gcagcggtag
     5281 cgtgacctta aaaaagacct gcgtgcgggt agccccctcc atcagcgccg cttcccgcgt
     5341 cgaggccgga atgctctgca acccggcgag gaaaaacagc atgtagtagc cggcgaactt
     5401 ccacacgccg atcagcgcca gggccagcag cgcgctgttg ctgcgcccca gccagttgtt
     5461 gttcatcggc ccgaacagct ttgccagata gtggtcgagc aggccgaggc cgggcataaa
     5521 gataaacagc cacagtgcag cggcgctgac catcgggata atcatcggga agaagaaggc
     5581 ggtgcgcagc caacggttga cgcgatggtt ctcgctcagg gcgaccgcca gcagcagggc
     5641 gagcgtcacc ccgggcatca ccgtcagcag gatatagagt aggttattgc ccagcgactg
     5701 ccagaagacg ttatcggcaa acaggcgggc aaagttatcc agcccgacgt attgcgcgtt
     5761 ggccatgcgg gtatcaaaca ggctgtcata caccgaacgc cccagcggaa accaggtaaa
     5821 cagcagtaaa aacagcaggg aaggcgacag gatcagccag ggaagccagg tctttctcat
     5881 ggttacgcac atctcgttca gccatttatc gaagccctaa ttgtgggaag ctatgattac
     5941 agaggtatga cggggaaacg atggtttgat gaagcaacgg ggaaaacgcc gggcgagcgg
     6001 gccgcccggt ggaggagaac catcataagt cggctttcag caccgcgcgg tagcgggctt
     6061 tgccttcgcg aacgtgtttc aacgcttcgt taatttgcga catagggaac agctcggtgg
     6121 tcggagccac tttgctgcgt ccggcgaact tcctcagcgt gcgcagttcg gatgggttac
     6181 cgatcgccga gccggagatg ctgcagtcgt cgccgataag ggtaaaggcc ggtaccggga
     6241 acggcttcat caccgcgtcg acggtgtgga agttgccgcc ctaggacagg gcttcgaagt
     6301 acggctgcca gtcaagatcc accgccacgg tgttgatgct caggtcaaac tgcccggcca
     6361 gcacttttaa ggcttcagga tcgcggctat tgactacgcg atcggcgccc atcgcccgca
     6421 gcagcttaat ggcgatatgg ccgaggccgc cgatgccgat cacccactgc cagtcggcac
     6481 gcagcttatt ggcgaagccg ccgcagcgcg cttggctgaa aaaaatgtcc tgctaacgcc
     6541 atccggcaga gcatccgccc tggcatttat gatgaccttg cgtgccgatc gtcgctataa
     6601 agacgctcaa ccgcttccct tggtaacctg acgcagttgc caattgacct gtcaatatga
     6661 gttcaccgga acgacacgaa tgaattcttg aactcacgca cagttcttat aaagatgatt
     6721 tcccagtcag ccc
//
LOCUS       DADXDL010000156         6472 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.156, whole genome shotgun sequence.
ACCESSION   DADXDL010000156 DADXDL010000000
VERSION     DADXDL010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6472
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.156"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            93..497
                     /gene="ybgC"
                     /locus_tag="IRB70_004577"
                     /pseudo
     CDS             93..497
                     /gene="ybgC"
                     /locus_tag="IRB70_004577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308798.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tol-pal system-associated acyl-CoA thioesterase"
     gene            494..1186
                     /gene="tolQ"
                     /locus_tag="IRB70_004578"
     CDS             494..1186
                     /gene="tolQ"
                     /locus_tag="IRB70_004578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolQ"
                     /protein_id="HBC0634403.1"
                     /translation="MTDMNILDLFLKASLLVKLIMLILIGFSIASWAIIIQRTRILNA
                     AAREAEAFEDKFWSGIELSRLYQESQGKRDNLTGSEQIFYSGFKEFVRLHRANSHAPE
                     AVVEGASRAMRISMNRELENLETHIPFLGTVGSISPYIGLFGTVWGIMHAFIALGAVK
                     QATLQMVAPGIAEALIATAIGLFAAIPAVMAYNRLNQRVNKLELNYDNFMEEFTAILH
                     RQAFTVSESNKG"
     gene            1190..1618
                     /gene="tolR"
                     /locus_tag="IRB70_004579"
     CDS             1190..1618
                     /gene="tolR"
                     /locus_tag="IRB70_004579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015965300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colicin uptake protein TolR"
                     /protein_id="HBC0634404.1"
                     /translation="MARARGRGRRDLKSEINIVPLLDVLLVLLLIFMATAPIITQSVE
                     VDLPDATESQAVSSNDNPPVIVEVSGIGQYTVVVEKDRLERLPPEQVVAEVSSRFKAN
                     PKTVFLIGGAKDVPYDEIIKALNLLHSAGVKSVGLMTQPI"
     gene            1683..2948
                     /gene="tolA"
                     /locus_tag="IRB70_004580"
     CDS             1683..2948
                     /gene="tolA"
                     /locus_tag="IRB70_004580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HBC0634405.1"
                     /translation="MSKATEQNDKLKRAIIISAVLHVILFAALIWSSFDENIEASAGG
                     GGGSSIDAVMVDSGAVVEQYKRMQSQESSAKRSDEQRKMKEQQAAEELREKQAAEQER
                     LKQLEKERLAAQEQKKQAEEAAKQAELKQKQAEEAAAKAAADAKAKAEADAKAAEEAA
                     KKAAADAKKKAEAEAAKAAAEAQKKAEAAAAALKKKAEAAEAAAAEARKKAATEAAEK
                     AKAEAEKKAAAEKAAADKKAAAEKAAADKKAAEKAAAEKAAADKKAAAEKAAADKKAA
                     AAKAAAEKAAAAKAAAEADDIFGELSSGKNAPKTGGGAKGNNASPAGSGNTKNNGASG
                     ADINNYAGQIKSAIESKFYDASSYAGKTCTLRIKLAPDGMLLDIKPEGGDPALCQAAL
                     AAAKLAKIPKPPSQAVYEVFKNAPLDFKP"
     gene            3081..4373
                     /gene="tolB"
                     /locus_tag="IRB70_004581"
     CDS             3081..4373
                     /gene="tolB"
                     /locus_tag="IRB70_004581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001646851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tol-Pal system protein TolB"
                     /protein_id="HBC0634406.1"
                     /translation="MKQALRVAFGFLILWASVLHAEVRIVIDSGVDSGRPIGVVPFQW
                     AGPGAAPEDIGGIVAADLRNSGKFNPLDRARLPQQPGSAQEVQPAAWSALGIDAVVVG
                     QVTPNPDGSYNVAYQLVDTGGAPGTVLAQNSYKVNKQWLRYAGHTASDEVFEKLTGIK
                     GAFRTRIAYVVQTNGGQFPYELRVSDYDGYNQFVVHRSPQPLMSPAWSPDGSKLAYVT
                     FESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLA
                     SGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEGSQN
                     QDADVSSDGKFMVMVSSNGGQQHIAKQDLATGGVQVLSSTFLDETPSLAPNGTMVIYS
                     SSQGMGSVLNLVSTDGRFKARLPATDGQVKFPAWSPYL"
     gene            4408..4929
                     /gene="pal"
                     /locus_tag="IRB70_004582"
     CDS             4408..4929
                     /gene="pal"
                     /locus_tag="IRB70_004582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan-associated lipoprotein Pal"
                     /protein_id="HBC0634407.1"
                     /translation="MQLNKVLKGLMIALPVMAIAACSSNKNASNDGSEGMLGAGTGMD
                     ANGGNGNMSSEEQARLQMQQLQQNNIVYFDLDKYDIRSDFAQMLDAHANFLRSNPSYK
                     VTVEGHADERGTPEYNISLGERRANAVKMYLQGKGVSADQISIVSYGKEKPAVLGHDE
                     AAYSKNRRAVLVY"
     gene            4939..5730
                     /gene="cpoB"
                     /locus_tag="IRB70_004583"
     CDS             4939..5730
                     /gene="cpoB"
                     /locus_tag="IRB70_004583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein CpoB"
                     /protein_id="HBC0634408.1"
                     /translation="MSSNFRHQLLSLSLLVGIAAPWAAFAQAPISSVGSGSVEDRVTQ
                     LERISNAHSQLLTQLQQQLSDNQSDIDSLRGQIQENQYQLNQVVERQKQILLQIDSLS
                     SGGAAAQSTSGDQSGAAASTTPTADAGTANAGAPVKSGDANTDYNAAIALVQDKSRQD
                     DAMVAFQNFIKNYPDSTYLPNANYWLGQLNYNKGKKDDAAYYFASVVKNYPKSPKAAD
                     AMFKVGVIMQDKGDTAKAKAVYQQVISKYPGTDGAKQAQKRLNAM"
     gene            5895..5970
                     /locus_tag="IRB70_004584"
     tRNA            5895..5970
                     /locus_tag="IRB70_004584"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:5928..5930,aa:Lys,seq:ttt)
     gene            6106..6181
                     /locus_tag="IRB70_004585"
     tRNA            6106..6181
                     /locus_tag="IRB70_004585"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6139..6141,aa:Val,seq:tac)
     gene            6184..6259
                     /locus_tag="IRB70_004586"
     tRNA            6184..6259
                     /locus_tag="IRB70_004586"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6217..6219,aa:Lys,seq:ttt)
     gene            6311..6386
                     /locus_tag="IRB70_004587"
     tRNA            6311..6386
                     /locus_tag="IRB70_004587"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6344..6346,aa:Val,seq:tac)
     gene            6390..6465
                     /locus_tag="IRB70_004588"
     tRNA            6390..6465
                     /locus_tag="IRB70_004588"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:6423..6425,aa:Lys,seq:ttt)
BASE COUNT         1719 a         1525 c         1772 g         1456 t
ORIGIN      
        1 ccttaacttg ccctcattcc caaacctcaa tcgcgcgcgt atagtagcag cgtttaaaag
       61 ctctaacttt tgttgcatta ccgggatgta aagtgaatac aacgctgttt tgatggccgg
      121 ttcgcgtcta ctatgaagat accgatgccg gtggtgtggt gtaccacgcc agttacgtcg
      181 ctttttatga aagagcacgc acagagatgc tgcgtcatca tcacttcagt caacaggcgc
      241 tgatggctga acgcgttgcc tttgtggtac gtaaaatgac ggtggaatat tacgcacctg
      301 cgcggctcga cgatatgctc gaaatacaga ctgaaataac atcaatgcgt ggcacctctt
      361 tggttttcac gcaacgtatt gtcaacgccg agaatacttt gctgaatgaa gcagaggttc
      421 tggttgtttg cgttgaccca ctcaaaatga agcctcgtgc gcttcccaag tctattgtcg
      481 cggagtttaa gcagtgactg acatgaatat ccttgatttg ttcctgaagg ctagccttct
      541 ggttaaactt atcatgttga ttttgattgg tttttcaatc gcatcctggg ccattattat
      601 ccagcggacc cgtattctta acgcagcggc gcgtgaagcc gaagcgtttg aagataaatt
      661 ctggtctgga atcgaacttt ctcgcctcta tcaagagagt caggggaaac gggataatct
      721 gactggttcg gaacaaatct tttacagcgg gttcaaagag tttgtgcgcc tgcatcgtgc
      781 caatagccat gcgccggaag ccgtagtgga aggggcgtcg cgtgctatgc gtatctccat
      841 gaaccgtgaa cttgaaaatc tggaaacgca cattccgttc ctcggtacgg ttggctccat
      901 cagcccgtat attggtctgt ttggtacggt ctgggggatc atgcacgcct ttatcgccct
      961 cggggcagta aaacaagcga cactgcaaat ggttgcgccc ggtatcgcag aagcgttgat
     1021 tgcgacggca attggtctgt tcgccgcaat tccggcggta atggcttata accgcctcaa
     1081 ccagcgcgta aacaaactgg aactgaatta cgacaacttt atggaagagt ttaccgcgat
     1141 tctgcaccgc caggcgttta ccgttagcga gagcaacaag gggtaagcca tggccagagc
     1201 gcgtggacga ggtcgtcgcg atctcaagtc cgaaatcaac attgtaccgt tgctggacgt
     1261 actgctggtg ctgttgctga tctttatggc gacagcgccc atcattaccc agagcgtgga
     1321 ggtcgatctg ccagacgcta ctgaatcaca ggcggtgagc agtaacgata atccgccagt
     1381 gattgttgaa gtgtctggta ttggtcagta caccgtggtg gttgagaaag atcgcctgga
     1441 gcgtttacca ccagagcagg tggtggcgga agtgtccagc cgtttcaagg ccaacccgaa
     1501 aacggtcttt ctgatcggtg gcgcaaaaga tgtgccttac gatgaaataa ttaaagcact
     1561 gaacttgtta catagtgcgg gtgtgaaatc ggttggttta atgacgcagc ctatctaaac
     1621 atctgcgttt cccttgcttg aaagagagcg ggtaacaggc gaacagtttt tggaaaccga
     1681 gagtgtcaaa ggcaaccgaa caaaacgaca agctcaaacg ggcgataatt atttcagcag
     1741 tgctgcatgt catcttattt gcggcgctga tctggagttc gttcgatgag aatatagaag
     1801 cttcagccgg aggcggcggt ggttcgtcca tcgacgctgt catggttgat tcaggtgcgg
     1861 tagttgagca gtacaaacgc atgcaaagcc aggaatcaag cgcgaagcgt tctgatgagc
     1921 agcgcaagat gaaggaacag caggctgctg aagaactgcg tgagaaacaa gcggctgaac
     1981 aggaacgcct gaagcaactt gagaaagagc ggttagcggc tcaggaacag aaaaagcagg
     2041 ctgaagaagc cgcaaaacag gccgagttaa agcagaagca agcggaagaa gcggcagcga
     2101 aagcggcggc agatgctaaa gcgaaggctg aagcggatgc aaaagctgcg gaagaagcag
     2161 cgaagaaagc ggctgcagac gcgaagaaaa aagcagaagc agaagccgcc aaagccgcag
     2221 ccgaagcgca gaaaaaagcc gaggcagccg cggcggcact gaagaagaaa gcggaagcgg
     2281 cagaagcagc tgcagctgaa gcaagaaaga aagcggcaac tgaagctgct gaaaaagcca
     2341 aagcagaagc tgagaagaaa gcggctgctg aaaaggctgc agctgataag aaagcggcag
     2401 cagagaaagc ggcagccgac aaaaaagcag cagaaaaagc ggctgctgaa aaggcagcag
     2461 ctgataagaa agcagcggca gaaaaagccg ccgcagacaa aaaagcggca gcggcaaaag
     2521 cagcagctga aaaagccgct gcagcaaaag ctgccgcaga ggcagatgat attttcggtg
     2581 agctaagctc tggtaagaat gcaccgaaaa cggggggagg ggcgaaaggg aacaatgctt
     2641 cgccagccgg gagtggtaat actaaaaaca atggcgcatc aggggccgat atcaataact
     2701 atgccgggca gattaaatct gctatcgaaa gtaagttcta tgacgcatcg tcctatgcag
     2761 gcaaaacctg tacgctgcgc ataaaactgg cacccgatgg tatgttactg gatatcaaac
     2821 ctgaaggtgg cgatcccgca ctttgtcagg ctgcgttggc agcagctaaa cttgcgaaga
     2881 tcccgaaacc accaagccag gcagtatatg aagtgttcaa aaacgcgcca ttggacttca
     2941 aaccgtaatc gcgatgttga ctgttccgac ggtcaacatc aggcaccggt tgccacgggg
     3001 ttctggtagt tttgtgtatt ttagtttgtt aacattctgc taaattatcg tgggccatcg
     3061 gtccagataa gggagatatg atgaagcagg cattacgagt agcatttggt tttctcatac
     3121 tgtgggcatc agttctgcat gctgaagtcc gcattgtgat cgacagcggt gtagattccg
     3181 gtcgtcctat tggagttgtt cctttccagt gggcgggccc tggtgcggca cctgaagata
     3241 ttggcggcat cgttgctgcc gacttgcgta acagcggtaa atttaatccg ttagatcgcg
     3301 ctcgtctgcc acagcagccg ggtagtgcgc aggaagtaca accagctgca tggtccgcgc
     3361 tgggtattga cgctgtagtt gtcggtcagg tcactccgaa tccggatggt tcttacaatg
     3421 ttgcttatca acttgttgac actggcggcg caccgggtac tgtacttgct cagaactcgt
     3481 acaaagtgaa caagcagtgg ctgcgttatg ctggtcatac cgccagtgat gaagtgtttg
     3541 aaaaactgac cggcattaaa ggtgcgtttc gtacccgtat tgcctacgtt gttcagacca
     3601 acggcggtca gttcccgtat gaactgcgcg tatctgacta tgacggttac aaccagtttg
     3661 tcgttcaccg ttcaccgcag ccgctgatgt ctccggcgtg gtcaccagac ggttctaaac
     3721 tggcttatgt gaccttcgaa agcggtcgtt ccgcgctggt tattcagacg ctggcaaatg
     3781 gcgctgtacg tcaggtggct tcattcccgc gtcacaacgg tgcacctgca ttctcgccag
     3841 acggcagcaa actggcattc gccttgtcga aaaccggtag tctgaacctg tacgtaatgg
     3901 atttggcttc tggtcagatc cgccaggtga ctgatggtcg cagtaacaat accgaaccga
     3961 cctggttccc ggatagccag aaccttgcat ttacttctga ccaggccggt cgtccacagg
     4021 tttataaagt gaatatcaac ggcggtgcgc cacaacgtat tacctgggaa ggttcgcaga
     4081 accaggatgc ggatgtcagc agcgacggta aatttatggt aatggttagc tccaacggtg
     4141 gacagcagca cattgccaaa caagatctgg caacgggagg cgtacaagtt ctgtcgtcca
     4201 cgttcctgga tgaaacgcca agtctggcac ctaacggcac tatggtaatc tacagctctt
     4261 ctcaggggat gggatccgtg ctgaatttgg tttctacaga tgggcgtttc aaagcgcgtc
     4321 ttccggcaac tgatggacag gtcaaattcc ctgcctggtc gccgtatctg tgataataat
     4381 taattgaata gtaaaggaat cattgaaatg caactgaaca aagtgctgaa agggctgatg
     4441 attgctctgc ctgttatggc aattgcggca tgttcttcca acaagaacgc cagcaatgac
     4501 ggcagcgaag gcatgctggg tgccggcact ggtatggatg cgaacggcgg caacggcaac
     4561 atgtcttccg aagagcaggc tcgtctgcaa atgcaacagc tgcagcagaa caacatcgtt
     4621 tacttcgatc tggacaagta cgatatccgt tctgacttcg ctcaaatgct ggatgcacat
     4681 gcaaacttcc tgcgtagcaa cccgtcttac aaagtcaccg tagaaggtca cgcggacgaa
     4741 cgtggtactc cggaatacaa catctccctg ggtgaacgtc gtgcgaacgc cgttaagatg
     4801 tatctgcagg gtaaaggcgt ttctgcagac cagatctcca tcgtttctta cggtaaagaa
     4861 aaacctgcag tactgggtca tgacgaagcg gcatactcca aaaaccgtcg tgcggtactg
     4921 gtttactaag agaattgcat gagcagtaac ttcagacatc aactattgag tctgtcgtta
     4981 ctggttggta tagcggcccc ctgggccgct tttgctcagg caccaatcag tagtgtcggc
     5041 tcaggctcgg tcgaagaccg cgtcactcaa cttgagcgta tttctaatgc tcacagccag
     5101 cttttaaccc aactccagca acaactctct gataatcaat ccgatattga ttccctgcgt
     5161 ggtcagattc aggaaaatca gtatcaactg aatcaggtcg tggagcggca aaagcagatc
     5221 ctgttgcaga tcgacagcct cagcagcggt ggtgcagcgg cgcaatcaac cagcggtgat
     5281 caaagcggtg cggcggcatc aacgacgccg acagctgatg ctggtactgc gaatgctggc
     5341 gcgccggtga aaagcggtga tgcaaacacg gattacaatg cagctattgc gctggtgcag
     5401 gataaatccc gccaggatga cgcaatggtg gcatttcaga atttcatcaa aaattaccct
     5461 gattcaactt acctgccaaa cgccaattat tggctgggtc agttaaacta caacaagggt
     5521 aaaaaagatg atgcggcgta ttattttgct tcggtagtga aaaactatcc gaagtcaccg
     5581 aaggctgcag atgcgatgtt taaagtcggc gtcatcatgc aggacaaagg tgacaccgca
     5641 aaagcgaaag ccgtatacca gcaggttatc agtaaatacc ctggtactga tggcgctaaa
     5701 caggcgcaaa aacgtctgaa cgcgatgtaa tgcataacac acgaccagaa gtcgcattat
     5761 ttctggtcgt gtcgtgcgaa tcataagcag ttgagtgatc tacatcgaaa tttttgttgc
     5821 gctcaagtct gaaatcagta atatatgccg ccgttgccac gggatatcaa acaaaccgaa
     5881 agcaacgaaa aagtgggtcg ttagctcagt tggtagagca gttgactttt aatcaattgg
     5941 tcgcaggttc gaatcctgca cgacccacca atcgctaagg tggaagcggt agtaaaacgt
     6001 gaaggataac gttgcgtcag caacggcccg aagggcgaga cgaagtcgag tcatcctgca
     6061 cgacccacca ctaacatagt tagttgtagt atccagcgta gtatcgggtg attagctcag
     6121 ctgggagagc acctccctta caaggagggg gtcggcggtt cgatcccgtc atcacccacc
     6181 accgggtcgt tagctcagtt ggtagagcag ttgactttta atcaattggt cgcaggttcg
     6241 aatcctgcac gacccaccac taattacggt gggttcggtg gaagtagttt gtagtatcca
     6301 gcgcagtatc gggtgattag ctcagctggg agagcacctc ccttacaagg agggggtcgg
     6361 cggttcgatc ccgtcatcac ccaccactcg ggtcgttagc tcagttggta gagcagttga
     6421 cttttaatca attggtcgca ggttcgaatc ctgcacgacc caccaatttt aa
//
LOCUS       DADXDL010000157         6195 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.157, whole genome shotgun sequence.
ACCESSION   DADXDL010000157 DADXDL010000000
VERSION     DADXDL010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6195)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6195)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6195
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.157"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1402)
                     /locus_tag="IRB70_004589"
     CDS             complement(<1..1402)
                     /locus_tag="IRB70_004589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBC0634409.1"
                     /translation="MSKYNELVKKLKEIFQIDRPELDFGIYRILNARADEINDYLDNK
                     LKAKIQSALADAGNANKSELEHQLQLTIKAATDAGVDPADSPKVQELKKQLAAMASGA
                     NEHENAVFSHLLTFFSRYYDNGDFISKRRYKGNTYAIPYSGEEVMLHWANKDQYYIKS
                     GENFANYSFKLEDGRKVSFKLLAADTAKDNRKDNELDRCFVLIEPHVRTKIDEEGDEY
                     EQEYKPVEVVKNSSVVDGKLVETEELVIHFEYKAMKKGTKQDALVQSAISTILADKTV
                     QQHWVDLAKRAPTEKNPSRTELERHLTTYTQRNTADYFIHKDLGGFLTNELDFYIKNE
                     VMNLDNVQNAEVFANVEKQLRMIQCLRAVALELITFLAQIENFQKKLWTKKKFVVGHE
                     YLVSLSNLSDSLYDKIRTNKGQHDEWVELYAVNKIPGYSFPFTKDFLYKNNGMILDTK
                     YFDPSFKEVFLTELTNV"
     gene            complement(1423..4314)
                     /locus_tag="IRB70_004590"
     CDS             complement(1423..4314)
                     /locus_tag="IRB70_004590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBC0634410.1"
                     /translation="MIGTTPYHAKYFAHELSILHSNNGVDRLSQSLFDASVDLNPHQI
                     EAALFAIENPLSKGVVLADEVGLGKTIEAGLVLCQLWAERKRKLLIICPASLRRQWAS
                     ELQEKFNLPSQVLDAKMYSQLQKEGIHNPLNNKSITIMSYHYAARLEEKLVAEMWDLV
                     VIDEAHKLRNAHRESNKMGQALKRALDGRKKLLLTATPLQNSLMELYGMSTLIDEHTF
                     GEVKAFRKQYMQADSDIAELKGRLSRFIKRTLRKNVLEYIKYTERKAITIPFYPSEQE
                     QDLYERVQKLLEREDSYALPKRHRHLTGLILRKLLSSSTKAVLNNLQILKTRLERLKL
                     EGIVEDDMDIIQQIIMDDDLEDDIVEDAESVAPDTECKSVDSDALQAEINELESLIVK
                     AEQIGTDTKSKELLSGLEQGFAQLAEMGAAKKVIIFTESMRTQQYLAHFLENNGYQGK
                     VVTFSGTNNTPQANKIYQQWREEYQGSSRITGSAQIDKRSALIDHFKDHAEIMIATEA
                     AAEGVNLQFCSLLINYDLPWNPQRIEQRIGRCHRYGQKFDVVVINFLNQRNQADQRVL
                     ELLTEKFSLFDGVFGASDSVLGSIENGVDFEKRIQSIYESCRTPEEIELAFERLQKEL
                     EDEINLKMQKTQEQLLEHFDEDIHDILKIRLDEARERLDKVGRWFWAVTCQQLKQYAD
                     FDHEHHRFTLRESVNELPVGQYQLLRKDGRQNSALQMQDHHSFAYRINHPLGEYVIDG
                     AKAQETKTAEVIFDYSNHTTKVSVAEQLKGQSGWLTLNLLTVDAFNRQQFLVFTAKTD
                     NGRVVDGEACKRLFNLSAITNEKLDNSASLDALPDDLILLKNRQIDARLAEVLEQNNV
                     LFEAERDKLEKWAEDMIFAAEEALRDTKMQIKSLKREARLAQSIEEQKQNQEKLKLLE
                     RQQKRQRMEIFDIEDEIADKRDELISALEERMKQKTDITELFTIRWKVI"
     gene            complement(4966..5124)
                     /locus_tag="IRB70_004591"
     CDS             complement(4966..5124)
                     /locus_tag="IRB70_004591"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634411.1"
                     /translation="MMMSDTTLSRPEVVSGHTDVIYSTSVCHILAVRKSTLLPIDTII
                     RHQVSDIS"
     gene            complement(5224..5400)
                     /locus_tag="IRB70_004592"
     CDS             complement(5224..5400)
                     /locus_tag="IRB70_004592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF957 domain-containing protein"
                     /protein_id="HBC0634412.1"
                     /translation="MKSLTTETALDILITWLQDNIDCESGIIFDNDEDKTGSAALLRC
                     IEQAREGIRTLRQQ"
     gene            complement(5417..5908)
                     /locus_tag="IRB70_004593"
     CDS             complement(5417..5908)
                     /locus_tag="IRB70_004593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312567.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634413.1"
                     /translation="MMKLALTLEADSVNVQALNMGRIVVDIDGVNLAELINMVCDNGY
                     SLRVVDESDRTSADCTPPFVALTGIRCSTAHITETDNAWLYSLSHQTSDFGESEWIHF
                     TGTGYLLRTDAWSYPVLRLKRLGLSKTFRRLVVTLIRRYGVSLIHLDASAGYLPGLPT
                     FDW"
     gene            complement(5905..>6195)
                     /locus_tag="IRB70_004594"
     CDS             complement(5905..>6195)
                     /locus_tag="IRB70_004594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin"
                     /protein_id="HBC0634414.1"
                     /translation="LLDQHYSLTLNDTPFVDERVIEQHIEAGISLCDAVNFLVEKYAL
                     VRTDQPGFSAGASSQLINSIDILRARRATGLMTRHNYRTVNNITLGKYPEAK"
BASE COUNT         1609 a         1460 c         1260 g         1866 t
ORIGIN      
        1 caacattagt taactctgtt aaaaaaacct ccttaaatga cggatcaaaa tattttgtat
       61 ccaatatcat accattattt ttatacaaga aatcttttgt gaatggaaat gaatatccag
      121 gaattttatt tacagcataa agctcaaccc attcatcatg ttgcccttta ttagttcgaa
      181 ttttatcgta aagcgaatct gatagatttg aaagtgacac aagatactca tgcccaacaa
      241 caaacttctt cttagtccaa agttttttct ggaaattctc aatttgtgcc aaaaatgtaa
      301 tgagttccag cgcaacagca cgcaaacatt gaatcatgcg caattgtttc tcaacattgg
      361 caaacacttc tgcattttgc acattatcga gattcattac ttcattttta atataaaaat
      421 ccagttcgtt cgttaaaaaa ccaccgagat ctttatggat aaagtagtct gctgtattac
      481 gctgggtata agttgtaagg tgacgctcca actctgtacg tgacggattc ttttctgttg
      541 gcgcacgttt agcaagatca acccaatgct gttgaactgt tttatctgcc agaattgttg
      601 aaatggcgga ctgtactaaa gcatcctgct tagtgccctt tttcattgcc ttatattcga
      661 agtgaataac taactcttct gtttcaacga gtttaccgtc caccacagat gagtttttca
      721 ccacttctac tggcttatat tcttgttcgt actcatcgcc ttcttcatca attttggtac
      781 gaacatgtgg ctcaataagt acaaagcagc gatctaattc attatcttta cggttatctt
      841 ttgctgtgtc cgctgcgagc aatttaaagc taactttacg accgtcttct aatttgaacg
      901 aataattagc gaagttttca ccgcttttaa tgtagtactg gtccttattt gcccagtgca
      961 acatcacttc ttcgccagaa taggggatgg cgtaggtatt acctttataa cggcgtttgc
     1021 tgataaaatc gccgttgtca taataacgcg aaaagaaagt gagcagatgg gaaaatactg
     1081 cattttcatg ctcatttgct ccggatgcca tagccgccag ttgcttttta agctcctgta
     1141 cttttgggct atcagcaggg tctacacccg catcagttgc cgcttttatt gtcagttgca
     1201 actgatgttc taattctgat ttattggcat ttcctgcatc cgccagcgca gactggattt
     1261 tggccttcag cttattatcc agatagtcgt taatttcatc agcacgcgca tttaaaatac
     1321 gataaatacc gaaatccagt tctggtcgat caatctgaaa aatttctttt agcttcttaa
     1381 ctaattcgtt gtacttactc attattttct ctttcaaatc aattaaataa ctttccagcg
     1441 gatggtaaac agctcggtga tatccgtctt ttgcttcatc cgctcttcaa gggcactgat
     1501 gagttcatcc cgcttgtcgg cgatctcatc ttcaatgtca aaaatttcca tacgttggcg
     1561 cttctgctgc cgttccagga gcttaagctt ttcctggttt tgcttttgtt cttcgatcga
     1621 ttgcgccagc ctggcttctc gcttcaacga cttgatttgc attttggtat cgcgtaatgc
     1681 ttcttccgcc gcaaagatca tgtcttcagc ccatttttcc agcttatctc tttccgcttc
     1741 aaaaaggaca ttgttctgct ccaaaacttc tgcaagcctg gcgtcaattt gcctgttctt
     1801 gagtaagatc aagtcatcag gtaatgcatc taaacttgcc gaattatcca gcttttcgtt
     1861 ggttattgca gacaagttga acagacgttt acaagcttca ccatctacca cacgtccgtt
     1921 gtcagttttc gcggtaaaga ctaaaaattg ctgcctgtta aacgcatcaa cagtaagcaa
     1981 atttagtgtt aaccatcctg attgcccttt cagctgctca gccaccgaaa ctttcgttgt
     2041 gtggttactg taatcgaaga tgacttcagc tgttttcgtc tcctgggctt tagctccgtc
     2101 aatgacgtac tcacccagtg gatgattgat ccgatatgca aaactgtggt gatcctgcat
     2161 ttgtaacgca ctattttgcc tgccatcttt gcgcaacagc tggtactgcc cgacaggcag
     2221 ttcattgact gattcacgta aagtgaaacg atgatgctca tgatcaaaat cagcatattg
     2281 tttgagctgc tgacaggtca cggcccaaaa ccaacgaccg actttatcca ggcgctcccg
     2341 agcttcatca agccttattt taaggatatc gtgaatatct tcatcaaaat gctcaagcaa
     2401 ctgttcttgc gtcttctgca tcttgagatt gatttcatct tccagctctt tctgcaacct
     2461 ttcaaaagcc agctctatct cctcgggggt acggcatgac tcataaattg actggatcct
     2521 tttttcaaaa tccacaccat tttctatgct gccaagcaca ctatccgatg cgccaaacac
     2581 gccatcaaac aggctgaact tttcagttaa gagttcaaga acgcgttgat cggcctggtt
     2641 tcgctgattg aggaagttaa taacaaccac atcaaatttt tgcccgtatc ggtgacaacg
     2701 tccaatacgc tgctcaatgc gttgtgggtt ccagggtaaa tcgtaattga tcagtagcga
     2761 acaaaattgc aggttcaccc cttcagctgc agcttctgta gctatcatga tttcagcatg
     2821 atctttgaag tggtcgatca aagccgagcg tttatcaatt tgcgccgacc cggtaatacg
     2881 agaagatccc tgatattcct cgcgccattg ctggtagatc ttgtttgcct gcggtgtatt
     2941 gtttgtgcca ctaaaggtta ctacttttcc ctggtagcca ttgttttcca gaaaatgtgc
     3001 aaggtactgt tgagttcgca tcgactccgt gaagatgatg actttttttg cagcccccat
     3061 ttcggcaagc tgtgcaaaac cttgctccag gccagaaagc aactcttttg atttggtatc
     3121 agtgccaatc tgttctgctt taacaatgag tgattccagc tcattgattt ctgcctgaag
     3181 cgcatctgaa tccacagatt tgcactctgt atctggcgct actgattcgg catcttcaac
     3241 gatgtcatct tcaagatcat catccattat gatctgttgg atgatgtcca tatcatcttc
     3301 aacgatacct tccagcttta acctttctaa acgagtctta aggatctgca agttattcaa
     3361 tacggctttc gtacttgagg aaagtagttt tctgagtata agccccgtca gatgccggtg
     3421 tcgttttggt aaggcatagc tatcctcacg ttcaagcaat ttttgtacgc gttcataaag
     3481 atcctgctcc tgttcgctcg gatagaaagg aatagtgatc gctttacgtt ctgtatactt
     3541 gatatactcc agcacattct tgcgtagagt tcgtttgata aaacgcgaca atcgcccctt
     3601 caactccgca atatcgctat ctgcctgcat atattgcttt ctgaacgctt taacttcgcc
     3661 gaaggtatgt tcatctataa gcgtcgacat gccatacagt tccatcaacg agttctgtaa
     3721 aggcgttgcg gtcagtagta atttcttccg cccatcaagc gcacgcttta acgcttgccc
     3781 cattttgttg ctttctcgat gagcattacg cagtttatgg gcttcgtcga taacaaccag
     3841 atcccacatt tcagccacca atttctcttc taaccgagca gcatagtggt atgacatgat
     3901 agtgatcgat ttattattta agggattatg gatcccttct ttttgaagct ggctatacat
     3961 tttcgcgtcc aacacctgag aaggtagatt gaacttttcc tgtaactcgc tcgcccattg
     4021 gcgacgcagt gaagcaggac aaatgatcaa cagtttacgt tttctttcag cccacaactg
     4081 gcaaagcact agtccagctt caatggtttt acccaaacca acttcatcgg caagcacaac
     4141 acctttgctt agcggatttt cgatagcaaa aagagccgcc tcaatttgat gagggtttag
     4201 atctacgctt gcatcaaaca gcgattgaga cagacggtcc accccattgt ttgaatgaag
     4261 aatggaaagt tcatgcgcaa aatatttcgc atgataaggt gttgtaccaa tcatcttttc
     4321 tctctcttcg ctgtactttg gacgataacc tgctgaattg aatcaagata ttaaaaggat
     4381 acgtcaatag tggttgatca ttgaagtaag gccatctccg gttgcgggac tttgacacat
     4441 aaaatcagca attttacgca tcgtttcatg actaaacaac gacgcactaa gaatgtcact
     4501 cgccaaatgc aatctatttc tgtgccatta gaccaaggca atgaagtttt atatctactt
     4561 aattttcagg atgatgaatg aacatcattg atggaaatgg ggcttccgaa gttcttagat
     4621 tatcagcgtt acatgcaaac aaagtagtga aaacacaggt acaaaaaaag ccgcccttga
     4681 gcgactcgat ttgcatacga tgtggtgcga aggccggact cgaacatgcg atttaacctc
     4741 atgatttaaa attgttaata ataaacaaca tcatcccata ccaacacaga taccaacacg
     4801 aaaaatcact ggttttcggc atcgaaccag gacaatcagg tcctgattga gataccgagc
     4861 tctgttactc gtcatcttcc tcgacaggct ccattgcatc aagtggtact cgcaccatcg
     4921 cgatagaacc aatccggata aaagcatctt ccccatctat atcggttaac tgatatcgct
     4981 tacttgatgc cggataattg tgtcgattgg caacagtgta ctctttcgta cagccagaat
     5041 gtggcagact gaggtggaat agataacgtc cgtatgcccg ctgaccacct ccgggcggga
     5101 gagtgtggta tctgacatca tcatttttcc tttctgttta taaatgaaaa cgccagccgt
     5161 gttcaggctg acgtcaggga agtgaaatcg ggtgagtgat cttcactggt tctggtgcaa
     5221 aagttactgt tggcgcaggg tacggatacc ctccctggcc tgttcgatac agcgcaacag
     5281 tgctgccgaa cctgttttat cctcatcgtt gtcgaagata attcccgatt cgcagtcgat
     5341 attgtcctgc agccacgtaa tcagaatatc cagcgctgtt tccgtggtta atgatttcat
     5401 gttgtgaatt tccggattac cagtcgaaag tgggtaaacc cggcagatat ccggcactgg
     5461 catccagatg aatgagactg acaccataac gccggatgag tgtgacgacc agacgacgga
     5521 acgtttttga cagccccagg cgcttaagcc gcagaaccgg gtatgaccac gcatcggtac
     5581 gtaacagata accggtaccg gtaaaatgaa tccattctga ttcaccgaag tcactggtct
     5641 ggtgtgacag cgagtacagc caggcgttgt ccgtttccgt gatatgtgcg gtactgcagc
     5701 gtatgccggt aagggcaaca aatggtggcg tgcagtctgc tgaggtccgg tcagattcat
     5761 caacaacacg aagggagtag ccgttatcgc agaccatgtt aatcagttca gcgagattaa
     5821 caccatcaat gtcaacgaca attcgcccca tattcagtgc ctgtacgtta acactgtcgg
     5881 cttccagtgt cagggccagt ttcatcattt cgcctccgga tacttaccca gggtgatatt
     5941 gttcaccgtt ctgtagttgt ggcgggtcat caggcctgtt gcccggcgag cccggagaat
     6001 atcaatgctg ttgattaact gcgacgaggc tcctgcgctg aatcccggct ggtcagttcg
     6061 taccagtgcg tatttttcca cgagaaagtt cactgcatca cacagtgaaa tgcctgcctc
     6121 aatatgctgc tcaatcacgc gttcatccac gaacggtgtg tcattcagcg taaggctgta
     6181 atgctggtcc agtaa
//
LOCUS       DADXDL010000158         6138 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.158, whole genome shotgun sequence.
ACCESSION   DADXDL010000158 DADXDL010000000
VERSION     DADXDL010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6138)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6138)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6138
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.158"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..258
                     /locus_tag="IRB70_004595"
     CDS             <1..258
                     /locus_tag="IRB70_004595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0634415.1"
                     /translation="LGTTVTSNDDTLALQSSAAGSAQNVGIQILDRTGEVLILDGATF
                     SAKTDLIDGTNILPFQARYIALGQSVAGTANADATFKVQYL"
     gene            621..1331
                     /locus_tag="IRB70_004596"
     CDS             621..1331
                     /locus_tag="IRB70_004596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus periplasmic chaperone"
                     /protein_id="HBC0634416.1"
                     /translation="MQTTRIPYSISFMATVLLLLLFACHSTIANAAVALGATRVIYPA
                     NQKQVLLPVTNNDPASVYLIQSWIENAGDQKDTQFVITPPLFSMQGKKENTLRIINAT
                     NHQLPGDRESLFWVNVKAIPAMEKDQKNENTLQLAIISRIKMFYRPTNLAMAPEEAPA
                     MLRFRRSGSKLTLINPTPYFITVTNMKAGNSNLPNTMVPPKGEVSVDIPHAATGDISF
                     QTINDYGALTPRIKATMQ"
     gene            1373..4024
                     /locus_tag="IRB70_004597"
     CDS             1373..4024
                     /locus_tag="IRB70_004597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310137.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial biogenesis outer membrane usher
                     protein"
                     /protein_id="HBC0634417.1"
                     /translation="MTAFRAAFKAYRMHQVLLLPRFARLTIALGLATAVFPVDAEYYF
                     NPRFLSNDLAESVDLSAFTKGREAPPGTYRVDIYLNDEFMTSRDITFIADDNNADLIP
                     CLSTDLLVSLGIKKSALLDNKEHSAEKHVSDNSACTPLRDRLADASSEFNVGQQHLSL
                     SVPQIYVGRMARGYVSPDLWEEGINAGLLNYSFNGNSINNRGNHNAGKSNYAYLNLQS
                     GINIGSWRLRDNSTWSYNSGSSNSSDSNKWQHINTSAERDIIPLRSRLTVGDSYTDGD
                     IFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTAQVSVKQNGYDVYQTTVPPGP
                     FTIDDINSAANGGDLQVTIKEADGSIQTLYVPYSSVPVLQRAGYTRYALAMGEYRSGN
                     NLQSSPKFIQGSLMHGLEGNWTPYGGMQIAEDYQAFNLGIGKDLGLFGAFSFDITQAN
                     TTLADGTRHSGQSIKSVYSKSFYQTGTNIQVAGYRYSTQGFYNLSDSAYSRMSGYTVK
                     PPTGDSNEQTQFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASRQSYWNTSRSDQQ
                     ISFGLNVPFSDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFRNSNA
                     SYSMSNDLKGGMTNLSGVYGTLLPDNNLNYSVQVGNTHGGNTSSGTSGYSSLNYRGAY
                     GNTNIGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLGDTMVLVKAPGADNVKIENQT
                     GIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQ
                     IGGKVLMTLKYGNKSVPFGAIVTHGQNKNGSIVAENGQVYLTGLPQSGKLQVSWGKDK
                     NSNCIVEYKLPEVSPGTLLNQQTAICR"
     gene            4038..4568
                     /locus_tag="IRB70_004598"
     CDS             4038..4568
                     /locus_tag="IRB70_004598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBC0634418.1"
                     /translation="MKYNNIIFLGLCLGLTTYSALSADSVIKISGRVLDYGCTVSSDS
                     LNFTVDLQKNSARQFPTTGSTSPAVPFQITLSECSKGTTGVRVAFNGIEDAENNTLLK
                     LDEGSNTASGLGIEILDGNMRPVKLNDLHAGMQWIPLVPEQNNILPYSARLKSTQKSV
                     NPGLVSASATFTLEFQ"
     gene            4581..5084
                     /locus_tag="IRB70_004599"
     CDS             4581..5084
                     /locus_tag="IRB70_004599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 fimbrial protein"
                     /protein_id="HBC0634419.1"
                     /translation="MKRLHKRFLLATFCTLFTATLQAADVTITVNGRVVAKPCTIQTK
                     EANVNLGDLYTRNLQQPGSASGWHNITLSLTDCPIETSAVTAIVTGSTDNTGYYKNEG
                     TAENIQIELRDDQDATLKNGDSKTVIVDEITRNAQFPLKARAITVNGNASQGTIEALI
                     NVIYTWQ"
     gene            5144..6058
                     /locus_tag="IRB70_004600"
     CDS             5144..6058
                     /locus_tag="IRB70_004600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0634420.1"
                     /translation="MGKTISIKVLFGIYFLLMAGKVFAFSCNVDGGSSIGAGTTSVYV
                     NLDPVIQPGQNLVVDLSQHISCWNDYGGWYDTDHINLVQGSAFAGSLQSYKGSLYWNN
                     VTYPFPLTTNTNVLDIGDKTPMPLPLKLYITPVGAAGGVVIKAGEVIARIHMYKIATL
                     GSGNPRNFTWNIISNNSVVMPTGGCTVDSRNVTVDLPDFPGSAEIPLGVYCSSEQKLS
                     FYLSGATTDSARQVFANTAPDATKASGVGVSLIRNGKILATGENVSLGTVNKSKVPLG
                     LSATYGQTGNKVAAGTVQSVIGVTFIYE"
BASE COUNT         1766 a         1329 c         1355 g         1688 t
ORIGIN      
        1 ctgggtacta ctgtcaccag taatgacgat accttagcgc tgcagagttc agcggcaggc
       61 tctgcccaaa atgtcggtat tcaaattttg gaccgtacgg gtgaggtatt aatacttgat
      121 ggtgccactt ttagcgctaa aactgacttg attgatggca cgaatatact gccattccag
      181 gctcgttata ttgctctcgg gcagtcagta gctggtactg caaacgctga tgcgaccttc
      241 aaagttcaat atctataatt caatcttaag gtggctatac gtcatctgaa attgaaacag
      301 ggtgtgtgtg gcatggctac gcacacccga gcaattcagc aatgttcatc tcattattaa
      361 tgaggaatag tttatatttt ggagcggtat gaaaaaatca cataatatct aaacgatcaa
      421 taaacaacag tagttaaact tactgttatt taaaatattt actttgtagc aaggttttcc
      481 tattaaaaga gaaccaacat ttattacaaa cgcattaagt ctggaaaccc ggcgagtcgc
      541 caatgtatta gcaacattta ccgattgtct gatgtaacgg tttccccgct tatcctctta
      601 acacatggag aatgcatcag atgcaaacta cgcgtatccc ctactctatt tcctttatgg
      661 cgacagtgtt acttttattg ctctttgctt gccatagcac cattgccaac gcagctgtcg
      721 cacttggtgc gacgcgggta atttatccgg caaaccagaa acaggtttta ttgcctgtca
      781 cgaataatga tcctgccagt gtctatctca ttcagtcatg gatagaaaat gcaggtgacc
      841 aaaaagacac ccagtttgtc attaccccac cgcttttttc catgcaaggt aaaaaagaga
      901 atacgcttcg gataatcaac gccactaatc atcagttacc aggcgaccgt gaaagcctgt
      961 tttgggttaa tgttaaagct attcctgcta tggaaaaaga ccagaagaat gagaatacat
     1021 tacagctggc aattattagc cgcataaaaa tgttttatcg cccgacgaac ctggcaatgg
     1081 cacctgaaga agcgccagca atgcttcggt ttcgtcgcag cggtagcaaa ctcactctta
     1141 ttaatccaac gccctacttc attaccgtaa caaatatgaa agcaggaaat agcaatctcc
     1201 caaacaccat ggtgccgcca aaaggtgaag tatcggtgga tatcccgcat gctgcaactg
     1261 gggatatcag ttttcagacg atcaatgatt acggtgcatt aactccgcgt attaaggcaa
     1321 ccatgcagta agccagtgac ctaattaata ataaactcaa tcggaattaa taatgacagc
     1381 ctttcgtgcc gcatttaagg catatcgtat gcatcaggtg ttactactgc ctcgctttgc
     1441 acggcttacc attgcccttg gcttagcaac tgcggtattt cccgttgacg cagagtatta
     1501 ttttaatcca cgctttttaa gcaatgatct tgctgaatct gtcgatttat ccgcctttac
     1561 taagggacgc gaggcaccac ctggtacata tcgggtcgac atttatttga acgacgaatt
     1621 tatgactagt cgggatatta cttttattgc agatgataat aatgcagatc tcatcccatg
     1681 cctgagtaca gaccttcttg tcagtcttgg cataaaaaaa tcagcattat tagacaataa
     1741 ggaacattcg gcagaaaaac atgtgtcgga caacagcgca tgcacaccac ttcgggatcg
     1801 tttggctgac gcatcatctg agtttaatgt tggtcagcaa catctgtcac tctccgttcc
     1861 gcaaatttat gttggcagaa tggctcgcgg ctatgtttct ccggatctgt gggaagaagg
     1921 aataaatgct gggctactaa actatagttt taatggtaat tctattaata atcgtggcaa
     1981 ccataatgca ggaaaatcca actatgcata tttgaattta cagagtggca tcaacattgg
     2041 tagttggcga ctgcgcgata actcaacgtg gagttataac agtgggagta gcaattcatc
     2101 tgacagcaat aaatggcagc atatcaatac gtcggctgaa cgtgacatta ttcccttacg
     2161 ctcacgctta acggtaggtg atagttatac cgatggcgat atttttgata gtgtgaactt
     2221 tcgtggcctc aaaataaatt caacagaagc gatgttgccc gatagccaac atggtttcgc
     2281 tccggtgatt catggtattg cccgcggcac cgcacaagtg agtgtaaaac agaatggata
     2341 cgatgtttat cagactactg tcccacccgg cccttttact attgatgata tcaactctgc
     2401 ggccaatggt ggtgatctgc aagtaaccat aaaagaggca gacggcagta ttcagacatt
     2461 atatgttcct tattcgtctg ttccggttct ccaacgtgct ggatatacgc gttatgcgct
     2521 tgccatgggg gaatatcgta gtggaaataa cctgcaaagc tcccccaagt tcatacaagg
     2581 tagcttgatg catggactgg aaggaaactg gacaccttat ggcggaatgc aaattgcaga
     2641 agattatcag gccttcaacc ttggtattgg taaagattta ggactttttg gtgccttttc
     2701 tttcgatatc acgcaggcca atacgacact tgcagatggc acccgtcaca gcgggcaatc
     2761 gattaaatcc gtctacagca aatccttcta ccagacggga accaatatcc aggtcgcagg
     2821 atatcgctat tctacgcaag gtttttataa cttatccgac agtgcctaca gtcgaatgag
     2881 tggttacacc gtcaagcctc ctaccggaga cagcaatgag cagacacaat ttattgatta
     2941 ttttaatctg ttctacagta agcgtggtca ggaacaaata agcatctctc agcagcttgg
     3001 aaattacggt acgacatttt tcagtgccag tcgccaaagt tactggaaca cgtcacgcag
     3061 cgaccagcaa atatcatttg gattaaatgt gccgtttagt gatattacga cttcgctgaa
     3121 ttacagctat tccaataata tatggcaaaa cgatcgggat catttacttg cttttacgct
     3181 taatgttccc ttcagtcatt ggatgcgtac agacagtcag tcggcatttc gtaactcaaa
     3241 cgccagttac agtatgtcaa acgatttgaa aggcggcatg accaatctat cgggagttta
     3301 tggcactctg ctgccggata ataacctgaa ttatagtgtt caggtcggta acacccacgg
     3361 gggtaataca tcgtctggca ccagtggtta cagttctctt aattatcgtg gagcttacgg
     3421 taatacgaat atcggttaca gtcggagtgg tgacagcagc cagatttatt acggaatgag
     3481 tggtggcatt attgctcatg ctgatggcat cacctttgga cagccgctgg gcgacacaat
     3541 ggttctggtt aaggctcctg gcgctgataa tgtcaaaata gagaaccaga ccggtattca
     3601 taccgactgg cgtggctatg ccatattacc atttgcgaca gaatatagag aaaatcgtgt
     3661 cgctcttaac gcgaattccc ttgcagataa tgttgaactg gatgaaaccg ttgtcactgt
     3721 catcccaact cacggtgcta ttgccagagc aacatttaat gcacaaatcg gcgggaaagt
     3781 attaatgacg ttgaagtacg gtaataagag cgttccattc ggtgcaattg tcacacatgg
     3841 acagaataaa aatggcagca ttgtcgcgga aaacggtcag gtttatctga ctggacttcc
     3901 acagtcaggg aaattacagg tttcatgggg caaagataaa aactcaaact gtattgtcga
     3961 gtacaagctt cctgaagttt ctcctggtac cttactgaac cagcagacag caatctgtcg
     4021 ctaaggaaca atagattatg aaatacaata acattatttt cctcggttta tgtctggggt
     4081 taaccaccta ttctgcttta tccgcagata gcgttattaa aattagcggg cgcgtcctcg
     4141 attatggctg cacagtctca tcggattcgc ttaattttac cgtagatctc caaaaaaaca
     4201 gtgccagaca atttccaacg accggtagca caagtccagc cgtccctttt cagattacat
     4261 taagtgaatg cagcaaaggg acaacgggag ttcgggttgc atttaacggt attgaggatg
     4321 cagaaaataa tactctgttg aaactggatg aaggaagcaa tacggcctcc ggtttgggta
     4381 tagaaatact ggacggaaat atgcgtccgg tgaaattgaa tgaccttcat gccgggatgc
     4441 agtggatccc attggtacca gaacagaaca atattttgcc ttactccgct cgtttgaagt
     4501 caactcagaa gtccgtcaat cctggactgg tgagcgcttc ggcaaccttt acccttgaat
     4561 ttcaataatc agagtcagat atgaaaagac ttcacaagag gttcctgtta gctacgtttt
     4621 gcacattatt cacagcaact ctccaggccg ccgatgtcac tatcactgtt aatggtcggg
     4681 tagtcgctaa accatgcact attcaaacca aagaagctaa cgttaatctc ggggatcttt
     4741 atacacgcaa tctgcaacaa cctggttctg catctggctg gcacaatatt actttgtcat
     4801 taaccgattg tccgattgaa acaagtgcag tgacggcaat cgtgacaggt tcaactgaca
     4861 atacgggtta ttacaaaaat gaaggtactg ccgaaaatat tcagatagag ctgagggatg
     4921 accaggatgc gacgttaaaa aatggcgata gcaaaacggt tattgttgat gagatcactc
     4981 gtaatgcaca gtttccactt aaggcaagag ctatcacggt gaatggaaac gcaagccagg
     5041 gaacgatcga ggcgctaatc aatgtgatct acacctggca ataacgtcga ttcgattttc
     5101 ttagccttct ttttaaatca attttttaac cttaggatat atcatgggta aaacaatcag
     5161 tataaaggtc ctgttcggta tttattttct attaatggca ggtaaagttt ttgccttcag
     5221 ttgtaatgtc gatggcgggt caagtattgg agctggtaca acctctgttt atgttaatct
     5281 cgaccctgta atacagccgg gccagaatct ggttgtagac ttgtctcagc atataagttg
     5341 ctggaatgat tacggcggct ggtacgacac tgatcatata aacctggtac aaggctcagc
     5401 tttcgcaggc tctctacagt catataaggg atcgctgtac tggaataatg tgacctaccc
     5461 cttcccgttg acgacaaata ccaacgtatt ggatattggt gataagacac cgatgccatt
     5521 accgttaaaa ctctatatta ccccagtcgg ggcggccggt ggagttgtca taaaagccgg
     5581 ggaagttatt gcccgtattc atatgtataa aattgccacg ttaggaagcg gaaatccgcg
     5641 taattttacg tggaatatta tttcaaataa cagtgttgtt atgccaacag gcggctgcac
     5701 tgttgatagt cgtaatgtca ccgtggatct cccggacttt cctggaagcg cagaaatacc
     5761 ccttggcgta tattgctcaa gcgaacaaaa gctctcattt tatctttcgg gtgccaccac
     5821 tgacagtgcc cgacaagtgt ttgctaacac ggcacctgat gcaacaaaag catcgggagt
     5881 gggtgtctct ctgatacgta atggaaaaat actggcaacg ggagaaaatg tctccctggg
     5941 gacagtaaat aaaagcaaag tacctctggg tttaagcgca acctatggac aaacaggaaa
     6001 caaggttgca gccggaaccg tccagtcagt cattggtgtc acttttatct atgaataatt
     6061 gtgattttga ccttagtcta tgcgctccat tcgcgaaaat tgcgcggata attattttgt
     6121 gaaggctatt atcctaca
//
LOCUS       DADXDL010000159         6063 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.159, whole genome shotgun sequence.
ACCESSION   DADXDL010000159 DADXDL010000000
VERSION     DADXDL010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6063)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6063)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6063
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.159"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            191..4598
                     /locus_tag="IRB70_004601"
                     /pseudo
     CDS             191..4598
                     /locus_tag="IRB70_004601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016244610.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter barrel domain-containing
                     lipoprotein"
     gene            5056..5322
                     /locus_tag="IRB70_004602"
                     /pseudo
     CDS             5056..5322
                     /locus_tag="IRB70_004602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005226947.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
     gene            5756..>6063
                     /locus_tag="IRB70_004603"
     CDS             5756..>6063
                     /locus_tag="IRB70_004603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fimbrial protein"
                     /protein_id="HBC0634421.1"
                     /translation="MKLKHVGMIVVSVLAMSSAAVSAAEGDESVTTTVNGGVIHFKGE
                     VVNAACAIDSESMNQTVELGQVRSSRLAKAGDLSSAVGFNIKLNDCDTNVSSNAAVAF
                     L"
BASE COUNT         1641 a         1254 c         1620 g         1548 t
ORIGIN      
        1 tttaaataaa ataagaacta tgcaattttt aatctatcaa ttcgaaagta ttagcaaatt
       61 agccaaattg acaccttccc acctccaacc aacactcaat acagacctct gacaatttaa
      121 taagtttcat ttttaatgtc tgacgactca tctctttcgt ggctgtattg tttgtatatg
      181 gagcgtttat atgaatagaa tctatcgcgt gatatggaat tgcaccctac aggcatttca
      241 ggtctgctcg gaattaactc gcagggtagg taaaacatcg acggttaatt tgcgtaaatc
      301 ctctggactg acaacgaaac tcagtagatt gacgctgggt gttttgctgg cactaagcgg
      361 ttcagcgtct ggtgcaagtc tggaagttga taatgatcag attaccaata ttgatactaa
      421 tgttgcttat gatgcctacc tggttggctg gtatggcact ggagtgctta atattttggc
      481 tggcggtaat gcctccttaa ccactattac taccagcgtc attggcgcta atgaggactc
      541 agagggcacc gttaatgttt tgggtggcac ctggcgattg tatgatagcg gaaataatgc
      601 aaggccttta aatgtgggtc aatccggaac ggggacgctg aatattaaac agaagggtca
      661 cgtcgatgga ggctatttaa gattaggtac tcaagctgca ggcgtcggga cggttaatgt
      721 tgaggaagag gactcggttt tgacgaccga attattcgaa atagggagtt acggtacggg
      781 ctcattaaat attacggata agggttacgt cacgagttca atcgtcgcca ttttaggcta
      841 tcaggcgggc agtaatggcc aggttgtcgt tgaaaagggc ggtgagtggc taatgaaaaa
      901 taacgattcc tcaattgaat ttcaaattgg taatcaagga actggggaag cgactattcg
      961 cgagggtggg ctaattacgg ctgaaaatac gattatcggt ggcaatgcca ccggtatcgg
     1021 aaccctgaat gtgcaggatc aagactctgt cattacggta cgcagactct ataatggata
     1081 tttcggtaat ggcaaagtca atatttccaa taatggactg attaataaca aagaatattc
     1141 attggtgggc gttcaggacg gttcccacgg tgtcgtcaac gtgaccgata aagggcattg
     1201 gaatttcctc ggaacgggcg aagctttccg ctatatctat atcggtgatg ctggcgacgg
     1261 tgaacttaat gtctctagtg aaggcaaagt cgattcggga attatcactg cggggatgaa
     1321 agaaacaggc acaggcaaca ttactgttaa ggataagaac tccgttatca ctaatctcgg
     1381 aactaatctt ggttatgacg gccacggcga aatgaatatc agtaatgagg ggcttgttgt
     1441 cagcaacgga ggaagctcac tcggttatgg agaaaccggc gtcgggaagg ttagcatcac
     1501 cacggggggg atgtgggagg tcaataagaa tgtctatacc actattggtg ttgcgggcgt
     1561 cggaaacctc aatatcagcg atggcggtaa gttcgtatcg caaaatatta cttttttggg
     1621 cgataaagca agcggtatcg gcacactgaa cctgatggat gcgacatcat cgttcgatac
     1681 tgtaggtatc aatgtcggta attttggtag cggcatcgta aatgtcagta atggtgccac
     1741 ccttaattca acgggctatg gatttatcgg aggaaatgcc tccggtaagg ggatagttaa
     1801 tatttcaacg catagtctct ggaatttaaa aacgtcatct actaacgccc aattgctaca
     1861 ggtcggtgta ttaggcacgg gtgaactgaa tattaccacc ggaggtatag ttaaagcgcg
     1921 tgatacacag atagctctga atgacaaaag taagggcgac gtgcgggtgg atgggcagaa
     1981 ctctcttctt gaaacattca atatgaacgt agggacgact ggcacaggta cgttaaccct
     2041 gacgaataac ggcacgctga atgtcgaagg tggagaagtt tacttaggtg tttttgagcc
     2101 tgctgtagga acgctaaaca ttggtgctgc tcacggtgag gtagcggcag atgccgggtt
     2161 tattaccaat gcgacgaaag tggagtttgg tcttggcgaa ggcgtttttg tctttaatca
     2221 taccaataac agtgatgccg gctaccaggt cgatatgctg attacgggtg acgataaaga
     2281 cggaaaagtg atgcatgatg caggccatac ggtgttcaat gcagggaata cttatagcgg
     2341 taaaacgctg gtcaatgacg gcctcctgac tattgcgtca catacggcag atggggtaac
     2401 aggcatgggt tcgagtgaag tcaccattgc aagccccggt acgctcgaca ttctcgcatc
     2461 aacgaacagc gcaggagatt acacgctgac caatgcgctc aaaggcgatg gcttgatgcg
     2521 agtgcagctg tcatcctccg acaagatgtt tggctttacc catgcaacag ggactgaatt
     2581 cgccggtgtt gcccaactga aagacagtac cttcactctg gaacgcgaca acaccgctgc
     2641 gcttactcac gcgatgttgc agtctgacat tgaaaatacc acatcggtaa acgtgggaga
     2701 gcaatccatt ggtggactgg ccatgaatgg cggtacgctc attttcgata cggatattcc
     2761 tgctgcgacg cttgcagagg gatatatcag cgtcgatacg ctggttgtcg gcgcgagtga
     2821 ctacacctgg aaaggccgta actataaggt aaacgggacg ggcgacgtgc ttatcgacgt
     2881 gcctaaaccg tggaatgatc ccatggcgaa taaccctctg acgacgctca atttgctgga
     2941 acacgatgat agccatgtcg gcgttcaact ggtgaaggcg caaacggtta ttgggtcggg
     3001 tggctcatta acgttacgtg atttacaggg cgacgaggtg gaagcggaca aaacgttaca
     3061 cattgcgcaa aacggaacgg tggtcgccga gggtgattat ggattccgcc tcacgaccgc
     3121 accaggtgat ggtttgtacg ttaactatgg gctgaaagcg ctgaacatcc atggagggca
     3181 aaagctgacg ttagccgaac atggcggagc ctatggcgca acggccgata tgtcggcaaa
     3241 aatcggtggt gaaggggatc tggcaatcaa tacggtgcga caggtttcgc tttccaacgc
     3301 tcagaacgac tatcaggggg caacctacgt tcagatgggg acattacgta ccgatgcgga
     3361 tggtgcactt ggcaacaccc gggaactgaa catcagcaac gcggccatcg tcgatcttaa
     3421 tggatcgacg cagacggtag agacattcac cgggcagatg ggttcgactg ttttgttcaa
     3481 agagggggcg ctgacggtaa ataaaggtgg gatcagtcag ggtgaactga caggtggcgg
     3541 aaacctgaat gttacagggg gaacgctggc tatcgagggg cttaatgcac gctacaatgc
     3601 gttaaccagc attagcccaa atgcggaagt cagcctcgat aatacgcagg ggttaggcag
     3661 cggaaatatt gccaataacg gtctgttaac gctaaaaaac gtgactggcg aactgcgcaa
     3721 tggcataagc gggaagggta tcgtgagcgc aaccgccagg acagatgtag agctggatgg
     3781 cgataatagc cgctttgtgg ggcaattcaa cattgataca ggcagcgcgc tcagcgtcaa
     3841 cgagcagaaa aacctgggtg atgcttccgt tatcaataat ggcctgctca ccatctccac
     3901 tgagcgtagc tgggcgatga cgcacagtat cagcggtagc ggtgatgtga caaaactggg
     3961 taccgggatc ctgactctta acaacgattc cgcggcgtat cagggtacga cggatatcgt
     4021 gggggggaaa ttgctttcgg ttccgactct gccattaata tggcaaggct aggcggcgat
     4081 ttggcgcagt ggagtagcaa cgcgcaggat cgctggcatc tcggcgtcat ggcaggctat
     4141 gccaatcagc acagtaatac tcagagtaat catgtgggtt ataaatcgga tgggcgcatc
     4201 agcggttaca gcgcaggact gtacgcgacc tggtatcaga acgatgcgaa taagaccggc
     4261 gcttatgttg acagctgggc gctgtataac tggtttgata acagcgtcag ttccgataac
     4321 cgttctgctg acgactacac cagcgtgaca atggtaaaca gcgtgagttc cagccttaca
     4381 ttgaagcgaa ctggatcaac aacagcaaag tctacgccgt gaagatgaat ggtcaaaccg
     4441 taagccgtga tggtgcgcgt aatctcggtg aagtacgtac cggggttgag gcgaaagtaa
     4501 ataacaacct tagcctgtgg gggaatgtcg gtgtgcaact aggtgataaa ggctatagcg
     4561 atactcaggg catgctgggt gtgaaatata gctggtaaac cgtataagcc gcatgtcgaa
     4621 gatgcatgcg gcttaatatt gccgacttca aacgactttt aaatcctcct ttttatccgc
     4681 gatcgcggat atcgcagcgt ttatcccgta gagcggataa gatgtagttg aaaccaatgt
     4741 gttgaggttg cacgaccggt taagccgaga atacggtatt aagtaagata tggggttttg
     4801 gtcgttgtta atgagcagga caatcatgac cgccaacgac tggattcttc cttggtttat
     4861 gttggtgcgc ataatgtata ttatgttaaa ttggatttga gtgatgcgaa gcgattttcc
     4921 ggtcgtcgtt attacttcag ggttccagaa cataaagcct ctcctctttc atgattggcc
     4981 tgtgcatacc ggatataggc tggctggtat gcaggtttgc cgtttgccgc atcttccctg
     5041 cgttgaagag tcaggctggc aaaccgcgtg caaatgaaca ccccctcttt ccatcaacac
     5101 ttcagacagc ttgcgggaat gagtccactc cggtatcaga aatggctacg cctcaatgaa
     5161 gccaggcgac tgatactgaa tgaacattac gatgtcacca ctgcagccta tgctgtcggt
     5221 tacgaaagct tatcccattt ctgtcgggaa tattcgcgga tgtttggaga gtcacctaag
     5281 agagatatta ccaggttaag aaagtctgtc ggtcagcttt aataaaccct gcacttatct
     5341 gtttagagca attccgtgtt agttacacca ggcaaacatt aactatagct aatgatttat
     5401 agccatataa gccattggtc gctcttgacc tttcctgaca cttcccttgt tcgcaataat
     5461 attctgttta gtcacggttt ataaataaca tgcataatga aatcgtcatg ttatttagcg
     5521 acataaaatg tctttgcaaa tactctctac aacaagtgct gcaataaact tgttgtgatt
     5581 aggtgtcctt gtaatttaaa gatattatcg ttcttcgtga aatgtaataa ccccggaaac
     5641 tatattctca gggcaatatc ccatcaagaa tgattcttgt tttataagca ataacagaat
     5701 gacttgattg ttaactttct ttattcagct acttaaatat aaattttgga gaattatgaa
     5761 actcaaacat gtcggtatga ttgtcgtttc tgtgttggcg atgtcgtctg ctgcggtaag
     5821 cgcagccgag ggtgatgaat cagtaacgac cactgttaat ggcggtgtta ttcattttaa
     5881 aggtgaagtg gtaaatgccg cttgtgcgat tgattcagaa tcaatgaacc aaacggttga
     5941 gctgggtcag gtccgttctt ctcgcctggc taaagcgggt gacctcagct ccgccgttgg
     6001 cttcaatatc aagctgaatg attgtgatac caatgtttcc agtaatgcag ctgttgcatt
     6061 cct
//
LOCUS       DADXDL010000160         6056 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.160, whole genome shotgun sequence.
ACCESSION   DADXDL010000160 DADXDL010000000
VERSION     DADXDL010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 6056)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6056)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6056
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.160"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(8..772)
                     /locus_tag="IRB70_004604"
     CDS             complement(8..772)
                     /locus_tag="IRB70_004604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001064798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBC0634422.1"
                     /translation="MNNQTIRTSVPALDKTVRVCNYLFSSPGATFSQIQQDLDLPKSS
                     TSSLLNALVEHHLLRQERGRFFLGLKLYEWGNRSLEQFDISKVARPVLEKLRDSTDLI
                     CHLGILDEVAPIYILKLESTQPIGIRTWVGKKLPLHSSGVGKALCAWLPQDVIDTLLP
                     EETLPRFTQTTITRKSDLIQEFARIRERGWAFDNAEDSPGIYCIAAPVFNQTREVIAA
                     ISISGVEIQIPKEKIEYYSTLVLDACQELSEKLKYI"
     gene            1012..1911
                     /locus_tag="IRB70_004605"
     CDS             1012..1911
                     /locus_tag="IRB70_004605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016246833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBC0634423.1"
                     /translation="MLTAFRGIFPPVPTIVDAQGKLDKAGMARMIDHVLENGANGMLI
                     LGSGGEFSQFSSQQRKEIAAFCLSHVDGKVPVLVGIACAGTAETIDLGHHAQEHGADG
                     VMVVNPYYAKLSDDARFMHYKSIADSLKIPVFLYNFPDLTGQDIGLEVITRLAREVPN
                     IVGIKDTIDNISHTREVINRVHAFRPDFIIFSGYDEYMLDTLLLGGHGGIPATFNFAP
                     NITRGIYQAVMENDLDKARSFQQQLAKLSPLYTLEQPFFGVIKTAIKLSGLDISTAVM
                     APALPLSDDKVARVKAILEHIHQ"
     gene            1928..3445
                     /locus_tag="IRB70_004606"
     CDS             1928..3445
                     /locus_tag="IRB70_004606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001044501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBC0634424.1"
                     /translation="MNKTPILKLNNSDDVVIARTELPAGSWLESESMETRDLIPAGHK
                     IALRDIPAGSAVKRYGQIIGFATRDIRQGEHIHVHNLGMGSFERDYAWGIDSHLPEKD
                     VHQDTFMGIRRKDGRVATRNYIGVLSSVNCSATVVRAIEDHFRTRGLSDYPNVDGIVA
                     LPQSFGCAFGSDSEMMKVMRRTMAGYATHANFAGIVIVGLGCESFQIKDMMNAHGLHE
                     SPVFHTMTIQESGGTRNAIEKGISFILDMLPEANNVKREPVPVSEIILALECGGSDSY
                     SGISANPALGYAVDRLVRQGGTAILSETSEIYGAEHLLTRRAISREVGEKLIRRIKWW
                     EEYCKRTGSEMNNNPSAGNKAGGLTTVLEKSLGGIAKAGTTSLMDVYEYAEPVTAKGL
                     VFMDTPGYDPMAVTGQIAGGANLLCFTTGRGSAFGAKPTPCLKLSTNNALWQRQRDDM
                     DLNCGTIVDGEETIEQVGERIYQRIIELASGHRSRSEELGYGSQEFVPWIMNSIM"
     gene            3523..4530
                     /locus_tag="IRB70_004607"
     CDS             3523..4530
                     /locus_tag="IRB70_004607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004093475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxythreonine-4-phosphate dehydrogenase
                     PdxA"
                     /protein_id="HBC0634425.1"
                     /translation="MERKPVLGIFLGEAAGIGPELVAKVVADGTVYKYCRPVLIGDAR
                     VLALGQEIAGVDFQWDVISDPTEADWTTGNVPLLDLKNFNPEKLTMGTIDTASGYATG
                     ESLVTCMSLLKSGKIDGFVFAPLNKEAFKKGGWDIEDEHYLFAEQLGYLDKPRGLLNV
                     LDDLWVFRVTGHIPFKDIASHITPENVSRSIQLCYDTLKMAGYKSPRIAVAALNPHAG
                     DGGTCGTEEIDVLIPVIEMFREKGMDMYGPVPGDTIFIHAFNHEYDAIVTLFHDQGQI
                     ATKLHSFDVGITVAAGLPFAITTPEHGTAFDIAGKGIAKTMATERAIAVAARMASTTQ
                     K"
     gene            4832..>6056
                     /locus_tag="IRB70_004608"
     CDS             4832..>6056
                     /locus_tag="IRB70_004608"
                     /inference="COORDINATES: protein motif:HMM:NF019310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0634426.1"
                     /translation="MSAYEKATNIRWRIFFVLFLLVVVSMIDRASISIAMPTIAKDLG
                     LSDTMQGLILSGFFWTYACMQIPGGFLADKFGARIILACSAILWGTAEALLGLCPTGF
                     ALLAANLLLGASEAPVFPSGARLNAIWLNKNERARGATLMDAGGPFGAAIGGILVAEM
                     MLYFTSWRITFIICGIAAITLGLIAYWVIRDRPEDSPRVNNKELGIINLDRVVQDTVE
                     ENNDPLLKVIPLRSFIGMLLGRCSWAMCFFGLLTWGPGYLTRALNLDLKAVGFATMIV
                     FCAGGCGSLCGGWLADKLASKGFGQARSCKFLLTVSGICTLISFALLPSIPDVKTSII
                     LLSCAAFVLMWGSMYWTFPPLLAPRSRVATVGGMMNMAGSVGGICIPLLVGLILDVTN
                     SFNPVLYFFAGCAVIF"
BASE COUNT         1700 a         1210 c         1415 g         1731 t
ORIGIN      
        1 attcaattca gatatatttt aatttttccg atagttcttg acacgcatca agaaccaaag
       61 ttgaataata ttcaattttt tctttaggta tctgaatttc cacgccacta atgctgatag
      121 ctgcaattac ttcacgagtc tgattaaata ccggagcagc aatacaataa attcccggtg
      181 aatcctctgc gttatcaaaa gcccatccac gttcacgaat acgtgcaaat tcctgtatta
      241 gatcagattt acgagtgata gttgtttgcg taaatcgtgg caacgtttcc tcaggcaaca
      301 atgtgtcaat gacgtcttga ggtaaccacg cacataaagc cttaccaact ccagaactat
      361 ggagtggcaa cttcttgcct acccacgttc tgatgccaat tggttgtgta ctctcgagtt
      421 tcaaaatata gattggagcg acttcatcga gaatgcccag atggcagata agatcagtac
      481 tgtctctcag tttttctaga accggcctcg ctaccttact gatgtcaaac tgctccagag
      541 atcgattccc ccattcatac aatttcagcc caagaaaaaa acgccctctt tcctgacgta
      601 acagatgatg ttcgacaagg gcattcagta aagatgatgt gctgcttttt ggcagatcca
      661 gatcctgctg gatctggctg aaggtggcgc ctggagagct aaaaaggtaa ttgcagactc
      721 tgacagtttt atcgagtgct ggtaccgatg ttctgatggt ttgattattc ataaaaaaat
      781 atgattcctt acaatactga atagtatacc ccattccccc ttgatgcgca gcggcgctta
      841 gcacacatat tatacatggc ctccgcgtac cggcatgcct ctataaacct gacttatttc
      901 acacttttca tatcgcattg taaaaacatt tgacatgcaa aacctgaatt tgattcactt
      961 tattcagcat aaagaactta tgttccatat acagaactta gtgagagtga tatgttgaca
     1021 gcgtttagag gtattttccc gccagttcct acaattgttg acgcacaagg gaaactagat
     1081 aaggctggca tggcccggat gatcgaccat gttttagaaa atggtgcaaa cgggatgttg
     1141 atccttggca gtgggggaga attctcacaa ttttcttccc agcaacgaaa agagatagct
     1201 gcattttgct taagtcatgt agatggcaaa gtgcctgttc tggtggggat cgcctgcgcg
     1261 ggaactgcag aaactattga tttaggacat catgcacagg agcacggagc tgatggtgtg
     1321 atggtggtga atccgtatta tgcaaaactc agcgatgatg cccggtttat gcattacaaa
     1381 tctattgccg attcacttaa aattccagtg tttctctata actttcctga tctgaccggt
     1441 caggatattg ggcttgaggt cattacccgg ctggcccggg aagttccaaa tatcgtgggt
     1501 atcaaggata ccatcgataa tatcagccat acccgggaag tcatcaaccg tgtacatgct
     1561 tttcgtccgg atttcattat attcagcgga tatgacgaat atatgctgga taccctgtta
     1621 ctgggcggcc atggtggtat tccggcgaca ttcaattttg ctccaaatat cacacgtggt
     1681 atttatcagg ccgttatgga aaatgatctt gataaagcac gttcttttca gcaacaactg
     1741 gcaaaactgt ctccgttata cacactggag cagcctttct ttggcgtgat aaaaactgcc
     1801 atcaaactga gtggactgga catatctact gcagttatgg caccggctct tccgctcagt
     1861 gatgacaagg tcgccagggt gaaagccatt ctggaacaca ttcaccagtg attacgagga
     1921 tcgtaagatg aataagactc cgatactcaa attaaataac tcggatgatg tcgttattgc
     1981 caggacagaa cttcctgccg gaagctggct ggaatctgaa agtatggaaa cacgtgacct
     2041 tattccggca gggcacaaaa ttgctcttcg ggatattccg gccggcagtg ccgttaaacg
     2101 ctatggacag ataatcggtt ttgcgacccg tgacatccga cagggcgaac atattcatgt
     2161 gcataatctc ggtatgggga gttttgagcg tgattatgcc tgggggatag acagtcatct
     2221 tccggaaaag gatgttcatc aggatacctt tatggggatc cgcagaaaag acggacgggt
     2281 ggcaacccgt aattatattg gtgtactgag ttctgtaaac tgtagtgcaa ccgtagtaag
     2341 ggcaattgaa gatcatttcc gtacccgtgg tctcagtgat taccctaatg tggatggtat
     2401 tgttgccctc ccacaaagtt ttggttgtgc ctttggctct gacagcgaaa tgatgaaagt
     2461 catgcggagg acaatggcag gctatgccac gcacgcgaac tttgccggga tcgtgatcgt
     2521 gggactggga tgtgaatcat tccagattaa ggacatgatg aatgcccacg gattacatga
     2581 aagtcctgta ttccatacaa tgactattca ggaaagcggc ggaacacgta acgctataga
     2641 aaaaggtatt tccttcattc tcgacatgct cccggaagcc aacaatgtca aacgagaacc
     2701 agttccggta tcagaaatca ttctggctct tgagtgtggc ggctctgata gctattcagg
     2761 aatttccgct aatccggctc tcgggtacgc agttgatcgc ctggttcgcc agggaggaac
     2821 ggctattctg tcggaaacat cggaaattta tggagcagaa caccttctga cacgccgtgc
     2881 cattagtcgc gaagttggcg agaaactaat ccgcagaatt aagtggtggg aagagtactg
     2941 taaacgtaca gggagtgaaa tgaataacaa cccttctgca ggtaataaag cggggggact
     3001 gaccactgtt ctggagaaat cgctgggagg gatagcaaaa gctggtacaa ccagcttaat
     3061 ggatgtgtat gaatatgctg aaccggtgac agcaaaaggg cttgtcttta tggatacccc
     3121 cggatatgac ccgatggcag taaccggaca aatcgccgga ggagccaacc tgctgtgttt
     3181 taccacgggc aggggatctg cctttggcgc aaaacccact ccttgtctga aactgtcaac
     3241 caataacgca ctatggcaac ggcagcgcga cgacatggat ttaaactgtg gcacgattgt
     3301 tgatggcgaa gaaacaatag aacaggttgg agaacgtatt tatcagagaa ttattgagct
     3361 ggcttcaggt catcgtagtc gaagtgaaga gctgggttat gggagccagg aattcgttcc
     3421 ctggataatg aactcaatca tgtaataact acaggcataa tttgttttgc ccggaaataa
     3481 ggaaacaaac tgaatcctgt ttttgataat tagaggtgaa taatggaacg taaaccagta
     3541 ctgggcattt ttttaggtga agctgccggc attggacctg aactggttgc caaagtcgta
     3601 gctgatggta ctgtctataa atattgcaga cctgttctga ttggcgatgc ccgggtactt
     3661 gctcttgggc aagagattgc tggtgtggat tttcagtggg atgtcatcag tgatcccact
     3721 gaagctgact ggactacggg aaatgtacca ttacttgatt tgaaaaattt taatcccgaa
     3781 aaactaacta tgggcaccat tgacactgcc tcaggttatg caacaggaga atcactggta
     3841 acctgtatgt cattacttaa atcaggtaaa attgacggtt ttgttttcgc tccactcaat
     3901 aaagaagcgt tcaagaaggg gggctgggat attgaggacg aacattatct ctttgctgag
     3961 cagttaggat acttggataa accacgtggc ctgttgaatg tccttgatga cctctgggtt
     4021 tttcgcgtga cgggacatat tccattcaaa gatattgcca gccatattac accagaaaat
     4081 gtcagtcgtt cgattcagtt atgctacgat acattaaaga tggcgggtta taaatcacct
     4141 cgcattgcag ttgcggcact aaatcctcat gctggtgatg gtggtacatg tggcactgag
     4201 gaaatagatg tacttatccc tgtaattgaa atgtttcggg agaaaggaat ggatatgtac
     4261 ggtcctgtcc caggggacac catctttatt catgcattta atcatgaata tgatgcgatc
     4321 gttaccctgt tccatgatca aggacaaatt gccaccaagc ttcattcctt tgatgtgggc
     4381 ataactgtag ccgccgggct tccatttgct ataacaacac cggaacatgg cactgcattt
     4441 gatattgcag gtaaggggat cgcaaaaaca atggctacag agagggctat tgctgttgca
     4501 gccagaatgg catcaacaac acagaaataa tttttataat agcagataat aatacaatat
     4561 ataacttata ttgagggata tagatattat ctgcattaaa atgagcttta taaaatgtct
     4621 ttataaagtt atcgcaagta atagtgactg tttaaaatag caatagacta ttttatcttc
     4681 taaggaatac gatacagtct attgttggac ttataggagc actacttctc ggaactattc
     4741 tttgttagta atttcgcaat caatatccag aaagtaaaat caaattttaa catatttagt
     4801 ctaataggtg tattattaaa ggagaataat tatgtccgcc tatgagaaag caacaaatat
     4861 aagatggaga atattttttg tacttttcct tcttgttgtt gtcagtatga ttgatcgagc
     4921 ctcaatatct atagctatgc ctactattgc taaagatctg ggattaagcg atacgatgca
     4981 aggactaatc ttgagtggtt ttttctggac ttatgcatgc atgcaaatac cgggtggatt
     5041 tttagccgat aaatttgggg caagaattat attagcatgc tcggcaatac tttggggaac
     5101 tgcagaagca ctattagggt tatgcccaac aggctttgcc ttacttgctg ctaatctatt
     5161 gcttggtgca agtgaagcac ctgtatttcc ttctggagcc agactgaatg caatctggct
     5221 taacaaaaat gaaagagctc ggggagcaac actaatggat gcaggagggc catttggtgc
     5281 tgcaattgga ggaatattag tagctgaaat gatgttatat tttacatcat ggcggattac
     5341 cttcattatt tgtggcatcg cagctataac tctggggcta atcgcatact gggttattcg
     5401 cgacaggcct gaagattcgc caagagtgaa taacaaagaa ctgggaatca ttaatctcga
     5461 tcgtgttgta caagatacag tagaagaaaa taatgatccc ttattaaaag tgattccact
     5521 acgttccttc atcggcatgc ttctaggccg ttgttcatgg gctatgtgtt tctttggttt
     5581 attaacatgg gggccgggat atcttacacg agcattaaac ctggatttaa aagccgttgg
     5641 gtttgccaca atgatcgttt tctgtgcagg tggttgtggt agcctttgtg gaggatggct
     5701 cgcagataaa cttgcaagta aagggttcgg acaggctaga tcatgtaaat ttctattaac
     5761 agtgtcaggt atctgcacgc ttatatcatt tgctttatta ccaagtattc ctgacgtaaa
     5821 aacatcgatt attttactgt cctgcgctgc atttgtttta atgtggggaa gtatgtactg
     5881 gacattccct cctttactgg caccccgttc tcgcgtagct accgtcggag gaatgatgaa
     5941 tatggcggga agtgttgggg gcatttgcat tcctttatta gtaggactta ttttagatgt
     6001 aacaaattca ttcaatcctg tactctattt ctttgctggt tgcgcagtga tattta
//
LOCUS       DADXDL010000161         5939 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.161, whole genome shotgun sequence.
ACCESSION   DADXDL010000161 DADXDL010000000
VERSION     DADXDL010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5939
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.161"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            131..577
                     /locus_tag="IRB70_004609"
     CDS             131..577
                     /locus_tag="IRB70_004609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBC0634427.1"
                     /translation="MAALTASCIDLNIQGNGAYSVLKQLATMALQNGFITDSHQFLQT
                     LLLREKMHSTGFGSGVAVPHGKSACVKQPFVLFARKTQAIDWQASDGEDVNCWICLGV
                     PQSGEEEQVKIIGTLCRKIIHQDFINQLRQGDADQVLALLNQTLSS"
     gene            588..2039
                     /locus_tag="IRB70_004610"
     CDS             588..2039
                     /locus_tag="IRB70_004610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose-like transporter subunit IIBC"
                     /protein_id="HBC0634428.1"
                     /translation="MESSLRIVAITNCPAGIAHTYMVAEALEQKARSLGHTIKVETQG
                     SSGIENRLSSEEIAAADYVILATGRGLSGDDRARFAGKKVYEIAISQALKNIDQIFSE
                     LPTNSQLFAADSGVKLGKQEVQSGSVMSHLMAGVSAALPFVIGGGILVALANMLVQFG
                     LPYTDMSKGAPSFTWVVESIGYLGFTFMIPIMGAYIASSIADKPAFAPAFLVCYLAND
                     KALLGTQSGAGFLGAVVLGLAIGYFVFWFRKVRLGKALQPLLGSMLIPFVTLLVFGVL
                     TYYVIGPVMSDLMGGLLHFLNTIPPSMKFAAAFLVGAMLAFDMGGPINKTAWFFCFSL
                     LEKHIYDWYAIVGVVALMPPVAAGLATFIAPKLFTQQEKEAASSAIVVGATVATEPAI
                     PYALAAPLPMITANTLAGGITGVLVIAFGIKRLAPGLGIFDPLIGLMSPVGSFYLVLA
                     IGLALNISFIIVLKGLWLRRKAKAAQQELVHEH"
     gene            2029..3099
                     /locus_tag="IRB70_004611"
     CDS             2029..3099
                     /locus_tag="IRB70_004611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBC0634429.1"
                     /translation="MNIELLQQLCEASAVSGDEQEVRDILINTLEPCVNEITFDGLGS
                     FVARKGNKGPKVAVVGHMDEVGFMVTHIDESGFLRFTTIGGWWNQSMLNHRVTIRTHK
                     GVKIPGVIGSVAPHALTEKQKQQPLSFDEMFIDIGANSREEVEKRGVEIGDFISPEAN
                     FACWGEDKVVGKALDNRIGCAMMAELLQTVNNPEITLYGVGSVEEEVGLRGAQTSAEH
                     IKPDVVIVLDTAVAGDVPGIDNIKYPLKLGQGPGLMLFDKRYFPNQKLVAALKSCAAH
                     NDLPLQFSTMKTGATDGGRYNVMGGGRPVVALCLPTRYLHANSGMISKADYDALLTLI
                     RDFLTTLTAEKVNAFSQFRQVD"
     gene            3099..4847
                     /locus_tag="IRB70_004612"
     CDS             3099..4847
                     /locus_tag="IRB70_004612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative frv operon regulatory protein"
                     /protein_id="HBC0634430.1"
                     /translation="MLNERQLKIVDLLKQQPRTPGELAQQTGVSGRTILRDIDYLNFT
                     LNGKARISASGNAGYQLEIFERRSFFQLLQKHDNDDRLLALLLLNTFTPRAQLASALN
                     LPETWVAERLPRLKQRYERGFCLASRPGLGHFIDETEEKRIILLANLLRKDPFLIPLS
                     GVTRDNFQQLTTACEKQRRWPLMQGDYLSSLILAIYALRNQLTDEWPQYPGDEIKQIV
                     EQSGLFLGDNAVRTLTGLIEKQHQQAQVISADHVLGLLQRVPGIASLNIIDTQLVENI
                     TGHLLRCLAAPVWIAEHRQSSMNNLKAAWPAAFDMSLHFITLLREQLDIPLFDSDLIG
                     LYFACALERHQNERQPIILLSDQNAIATINQLAIERDVLNCRVIIARSVSELVAIREE
                     IEPLLIINNSHYLLDDAVNNCITVKNIITAAGIEQIKHFLATAFIRRQPERFFSAPGS
                     FHYSNVRGESWQHITRQICAQLVAQHHITADEAQRIIAREGEGENLIVNRLAIPHCWS
                     EQERRFRGFFITLAQSVEVNNEVINHVLIACAAADARHELKIFSYLASVLCQHPAEVI
                     AGLTGYEAFMELLHKG"
     gene            complement(4897..>5939)
                     /locus_tag="IRB70_004613"
     CDS             complement(4897..>5939)
                     /locus_tag="IRB70_004613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="YiiG family protein"
                     /protein_id="HBC0634431.1"
                     /translation="LSSAIIVAIMALGLTGCDDKKAETETPPPANSQPAAPAPEAKPA
                     EAPVAKAEVKPETPAQPVVDEQAVFDEKMDVYIKCYNKLQIPVQRSLARYADWLKDFK
                     QGPTGKESTVYGIYGISESSLAECEKGVKSAVALTPALQPIDGVAVSYIDAAVALGNT
                     INEMDKYYTQENYKDDAFAKGKTLHQTFLKNLEAFEPVAESYHAAIQEINDKRQLAEL
                     KNIEEREGKTFHYYSLAVMISAKQINNLISQEKFDVDAAMKKVSELETLVAQAKEADK
                     GGMNFSFINSAGQYQLEAKKYVRRIRDKVPYSDWDKEQLQDANSSWMVEDSFPRALRE
                     YNEMVDDYNRLR"
BASE COUNT         1376 a         1520 c         1518 g         1525 t
ORIGIN      
        1 tgtgccttac accgcaaaat ttatccttca ctctgcctta tattgtcacg acttcacgac
       61 atatccgcgc tcatcacaaa accgccccgc cgttacaatt aactattata ttttttcatg
      121 gaatccaata atggcagcac ttactgcaag ctgtattgac ctgaatattc agggcaatgg
      181 cgcttattcc gttctgaagc agttggcgac aatggcgtta caaaacggtt ttatcaccga
      241 ctcacaccag ttcctgcaaa ccctgctgct gcgcgaaaaa atgcactcca cgggatttgg
      301 ttccggtgtc gccgtgccgc acggtaaaag cgcctgcgtt aaacaaccgt tcgtgttatt
      361 cgcccgcaaa acgcaggcca ttgactggca ggccagcgat ggcgaagacg tcaattgctg
      421 gatctgcctc ggcgtgccac aaagtggcga agaggaacag gtcaaaatca tcggcacgct
      481 gtgccgcaaa attatccacc aggattttat caaccaactg cgacagggcg acgccgacca
      541 ggtacttgct ttgttaaatc aaaccctcag ctcataagga agtggcgatg gagtcatcct
      601 tacgtattgt cgcgatcacc aactgccccg ccgggatcgc tcacacctac atggtggcgg
      661 aagccctgga acagaaagcc cgttctctcg gtcataccat taaagttgaa actcaaggat
      721 caagcggcat cgaaaaccgc ttatccagcg aagagattgc cgctgccgat tacgtgattc
      781 tcgctaccgg gcgtggcctg agcggtgatg atcgcgcgcg atttgccggg aaaaaggttt
      841 atgagattgc catctcccag gcgctgaaaa atatcgacca gattttcagt gaattaccga
      901 caaactcgca gctttttgcc gcagatagcg gcgtgaagct cggcaaacag gaagtgcaaa
      961 gtggcagcgt aatgagccat ctgatggcgg gtgtttctgc ggcgctgccg tttgtcatcg
     1021 gtggcggtat cctggtggcg cttgccaaca tgctggtgca gttcggtttg ccgtataccg
     1081 atatgtcgaa aggcgcgccg tcgtttacct gggtggtgga atccatcggt tatctcggct
     1141 tcacctttat gatccccatc atgggcgctt atattgcctc gtcgattgcc gataaaccgg
     1201 ctttcgctcc ggcgtttctg gtttgctatc tggcgaatga caaagccctg ctcggcaccc
     1261 agtctggcgc gggcttcctc ggtgcggtgg tgctggggct ggcgattggc tatttcgtct
     1321 tctggttccg taaagtgcgc cttggcaaag cattacaacc gctgctcggt tccatgctga
     1381 tcccgttcgt cactctgctg gttttcggcg tactgactta ctacgttatc ggaccggtga
     1441 tgtccgacct catgggcggg ttgctgcact tcctgaacac cattcctccg tcaatgaagt
     1501 ttgcggcagc gtttttggtc ggtgcgatgc tggcgttcga tatgggcggt cctatcaata
     1561 aaaccgcctg gttcttctgc ttctcactgc tggaaaaaca catttacgac tggtacgcca
     1621 tcgtcggcgt tgtcgcgctg atgccgcctg tcgcggcggg tcttgcgacg ttcattgcgc
     1681 ccaagctgtt tactcaacag gaaaaagaag ccgccagtag cgccattgtg gtcggtgcca
     1741 cggtcgcgac cgaaccggct attccttacg ctctggcggc accactgcca atgatcaccg
     1801 ccaatacgct ggcgggcggc attaccggcg tgctggtgat cgctttcgga atcaaacgac
     1861 tggcacctgg tttgggtatc tttgacccgc tgatcggcct gatgtcgccg gtaggttcgt
     1921 tttacctggt gctggcgatt ggcctcgcgc tgaacatttc attcattatc gtcctgaaag
     1981 gattatggtt acgccgcaaa gccaaagctg cgcaacagga gcttgtccat gaacattgag
     2041 ttactgcaac agttgtgcga agccagcgcc gtcagcggcg atgaacagga agttcgcgac
     2101 attctgataa acacgctgga accttgcgtt aatgagatca cctttgatgg tctgggcagc
     2161 tttgttgccc gtaaggggaa taaagggcca aaagttgccg ttgtcgggca tatggatgaa
     2221 gtcggcttta tggtcaccca catcgacgag agcggttttt tgcgtttcac caccattggt
     2281 ggctggtgga atcagtcgat gctcaaccac cgggtaacca tacgcacaca caagggagtg
     2341 aaaatccctg gtgtgattgg ttccgtcgcg cctcatgcgt taaccgaaaa gcaaaagcaa
     2401 caaccgctgt catttgatga gatgttcatt gatattggcg cgaacagtcg cgaagaggtg
     2461 gaaaagcgcg gcgtggaaat tggcgatttt attagcccgg aagccaattt tgcctgctgg
     2521 ggcgaagata aagtggtcgg caaggcgctg gataaccgca tcggctgcgc gatgatggct
     2581 gagctactac agacagtaaa taaccccgaa attacgctgt atggcgtcgg cagcgtggaa
     2641 gaagaagttg ggctacgcgg ggcacaaacc tcggcggaac acattaaacc ggacgtcgtg
     2701 atcgtgttgg ataccgccgt agcgggcgat gttccgggca ttgataacat aaaatacccg
     2761 ctgaaactgg gccaggggcc ggggctgatg ctgtttgaca agcgctactt ccccaaccag
     2821 aaactggtgg cggcgttaaa aagctgtgcc gcacataacg atttaccgct gcaattttcc
     2881 accatgaaaa ccggagcgac ggatggcggg cgctacaacg tgatgggcgg cgggcgtcca
     2941 gttgtcgcgc tgtgtctgcc aacgcgttat ctgcacgcca atagcggtat gatttcaaaa
     3001 gccgattacg atgctctgct cacgttgata agggattttc tgaccacctt aaccgcggag
     3061 aaagtcaacg cgtttagcca gttccgtcag gtggattaat gctaaacgaa cgccagttaa
     3121 agattgtcga tctgctgaag caacagccac gcacgcctgg cgagctggcg caacagactg
     3181 gcgtttccgg caggaccatc ctgcgtgata ttgactatct caactttacc cttaacggca
     3241 aagcccgcat ttccgccagt ggcaacgcgg gctatcagct ggaaatcttc gagcgccgca
     3301 gcttttttca gttgctgcaa aagcacgata acgacgatcg gctgctggcg ctgttattac
     3361 tgaatacctt cactccccgt gcgcaactcg cctcggcgct taatttgcca gaaacgtggg
     3421 tagcagagcg cctgccccgc ctgaaacagc gctatgaacg cggtttttgt ctcgctagtc
     3481 gccctggttt gggccatttc attgatgaga cagaagagaa acgcattatt ttgctggcga
     3541 atcttttacg caaagatccg tttttaattc cgctgtcggg cgtaacacga gacaattttc
     3601 aacaattaac caccgcctgc gaaaagcaac gtcgctggcc gctgatgcaa ggcgactatc
     3661 tctcaagcct gattctggcg atttacgccc tgcgtaatca actgaccgat gagtggccgc
     3721 aatatcccgg tgacgagata aaacaaatcg ttgaacagag cggcctgttt cttggtgata
     3781 acgctgtaag aaccctgaca ggtttgatag agaaacagca tcagcaagcg caggtaattt
     3841 ctgccgatca tgtgctgggg ttgctgcaaa gggtgccagg catcgcgtca ttgaatatta
     3901 ttgatacgca gttggttgag aatattaccg ggcatttatt acgttgcctt gccgcaccgg
     3961 tgtggattgc cgagcaccgc caaagcagca tgaataacct gaaagccgcc tggcctgcgg
     4021 cctttgatat gagtctgcac tttattacgc tactgcgtga acaactcgat attccccttt
     4081 tcgacagcga tctgattggt ttgtattttg cctgtgcgct ggaacggcat caaaacgaac
     4141 gccagccgat cattttgctc tctgatcaga acgcgattgc tactattaat cagctcgcca
     4201 ttgagcgcga tgtcctgaat tgtcgggtga ttattgcccg cagcgtaagc gaactggttg
     4261 ccattcgcga agagattgag ccgttattga tcattaataa cagccattat ttactggatg
     4321 atgcggtcaa taattgcatc accgtaaaaa acattattac tgccgccggt atcgaacaaa
     4381 taaaacattt tctggcgacg gcgtttattc gccggcaacc ggagcgtttt ttctctgccc
     4441 ccggaagttt tcattattcg aatgtacgcg gtgaaagctg gcaacatatt acccggcaaa
     4501 tttgtgctca attagtcgca caacaccata ttaccgccga tgaagcgcaa cggatcatcg
     4561 cccgcgaagg cgaaggtgaa aacctgattg ttaatcgcct cgccatccca cattgctgga
     4621 gcgaacagga gcgacgtttt cgtggatttt ttattaccct cgcccaatca gttgaggtga
     4681 ataacgaagt cattaaccat gttttgatcg cctgcgccgc cgccgatgcg cgtcatgagc
     4741 taaaaatatt tagctatctg gcaagcgtat tgtgtcagca tccggcagag gttattgccg
     4801 ggttaacagg atatgaggca tttatggagt tacttcacaa ggggtgaact gtgtcggatg
     4861 cgccgcatcc gacactgcat ttatcatcaa aaacgtttaa cgcaggcgat tataatcatc
     4921 gaccatttcg ttgtactcgc gtaatgctct cgggaaagag tcttcgacca tccagcttga
     4981 gtttgcgtcc tgaagttgct ctttatccca gtcagagtac gggactttat ctctgatgcg
     5041 gcgaacgtat tttttagcct cgagttgata ctggcctgcc gaattaataa acgagaaatt
     5101 catgccgcct ttatccgctt ctttggcctg cgccaccagc gtttccagtt cagacacttt
     5161 cttcattgcc gcatcaacat caaacttctc ttgcgatatc aggttattaa tttgtttcgc
     5221 tgaaatcatg actgccagag aatagtagtg gaatgttttc ccttctcttt cttcaatatt
     5281 tttcagttcc gcaagctgac gcttatcatt aatttcctgg atcgccgcat gataagattc
     5341 ggctacaggt tcaaaggctt ccagattttt taagaatgtc tggtgcagcg ttttcccttt
     5401 cgcaaacgca tcgtctttat aattttcctg ggtgtaatat ttatccattt cgttaatggt
     5461 attacccaac gccacggcag catcgatata actcaccgct acgccatcaa taggttgcag
     5521 cgcaggcgtt aacgccacag cactttttac gcctttttca cactcagcga ggctggattc
     5581 actaatgccg tagatgccat aaacagtact ctctttaccg gtaggcccct gtttaaaatc
     5641 tttcagccag tcagcataac gcgccagact gcgctgtacc gggatctgta acttgttgta
     5701 gcacttgata tagacatcca ttttttcgtc gaaaaccgct tgttcatcga ccaccggttg
     5761 ggcaggcgtt tcaggtttaa cttctgcttt tgcaacggga gcttcagcag gtttcgcttc
     5821 aggagctggt gcggcaggtt gactattggc aggcgggggc gtttctgttt cggctttttt
     5881 atcatcacaa cccgtgagac cgagggccat gatggcgact ataatagcgg aagataata
//
LOCUS       DADXDL010000162         5546 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.162, whole genome shotgun sequence.
ACCESSION   DADXDL010000162 DADXDL010000000
VERSION     DADXDL010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5546
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.162"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(36..773)
                     /gene="bamD"
                     /locus_tag="IRB70_004614"
     CDS             complement(36..773)
                     /gene="bamD"
                     /locus_tag="IRB70_004614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="outer membrane protein assembly factor BamD"
                     /protein_id="HBC0634432.1"
                     /translation="MTRMKYLVAAATLSLFLAGCSGSKEEVPDNPPNEIYATAQQKLQ
                     DGNWRQAITQLEALDNRYPFGPYSQQVQLDLIYAYYKNADLPLAQAAIDRFIRLNPTH
                     PNIDYVMYMRGLTNMALDDSALQGFFGVDRSDRDPQHARAAFSDFSKLVRGYPNSQYT
                     TDATKRLVFLKDRLAKYEYSVAEYYTERGAWVAVVNRVEGMLRDYPDTQATRDALPLM
                     ENAYRQMQMNAQAEKVAKIIAANSSNT"
     gene            908..1888
                     /gene="rluD"
                     /locus_tag="IRB70_004615"
     CDS             908..1888
                     /gene="rluD"
                     /locus_tag="IRB70_004615"
                     /EC_number="5.4.99.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017383977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA pseudouridine(1911/1915/1917) synthase
                     RluD"
                     /protein_id="HBC0634433.1"
                     /translation="MAQRVQLTATVSENQLGQRLDQALAEMFPDYSRSRIKEWILDQR
                     VLVNGKVCDKPKEKVLGGEQVAINAEIEEEARFEPQDIPLDIVYEDDDIIVINKPRDL
                     VVHPGAGNPDGTVLNALLHYYPPIADVPRAGIVHRLDKDTTGLMVVAKTVPAQTRLVE
                     SLQRREMTREYEAVAIGHMTAGGTVDEPISRHPTKRTHMAVHPMGKPAVTHYRIMEHF
                     RVHTRLRLRLETGRTHQIRVHMAHITHPLVGDPVYGGRPRPPKGASEAFISTLRKFDR
                     QALHATMLRLYHPISGIEMEWHAPIPQDMVELIEVMRADFEEHKDEVDWL"
     gene            1885..2616
                     /gene="pgeF"
                     /locus_tag="IRB70_004616"
     CDS             1885..2616
                     /gene="pgeF"
                     /locus_tag="IRB70_004616"
                     /EC_number="1.10.3.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyphenol oxidase"
                     /protein_id="HBC0634434.1"
                     /translation="MSKLIVPQWPLPKGVAACSSTRIGGVSLPPYDSLNLGAHCGDNP
                     DHVEENRKRLFAAGNLPSKPVWLEQVHGKDVLKLTGEPYASKRADASYSNTPGTVCAV
                     MTADCLPVLFCNRAGTEVAAAHAGWRGLCAGVLEETVSCFADNPENILAWLGPAIGPR
                     AFEVGAEVREAFMAVDAEASTAFIQHGDKYLADIYQLARQRLASVGVEQIFGGDRCTY
                     TENETFFSYRRDKTTGRMASFIWLI"
     gene            2746..5319
                     /gene="clpB"
                     /locus_tag="IRB70_004617"
     CDS             2746..5319
                     /gene="clpB"
                     /locus_tag="IRB70_004617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002461515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBC0634435.1"
                     /translation="MRLDRLTNKFQLALADAQSLALGHDNQFIEPLHLMSALLNQEGG
                     SVSPLLTSAGINAGQLRTDINQALNRLPQVEGTGGDVQPSQDLVRVLNLCDKLAQKRG
                     DNFISSELFVLAALESRGTLADILKAAGATTANITQAIEQMRGGESVNDQGAEDQRQA
                     LKKYTIDLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEG
                     LAQRIINGEVPEGLKGRRVLALDMGALVAGAKYRGEFEERLKGVLNDLAKQEGNVILF
                     IDELHTMVGAGKADGAMDAGNMLKPALARGELHCVGATTLDEYRQYIEKDAALERRFQ
                     KVFVAEPSVEDTIAILRGLKERYELHHHVQITDPAIVAAATLSHRYIADRQLPDKAID
                     LIDEAASSIRMQIDSKPEELDRLDRRIIQLKLEQQALMKESDEASKKRLDMLNEELSD
                     KERQYSELEEEWKAEKASLSGTQTIKAELEQAKIAIEQARRVGDLARMSELQYGKIPE
                     LEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLARWTGIPVSRMMESEREKLLRMEQEL
                     HHRVIGQNEAVDAVSNAIRRSRAGLADPNRPIGSFLFLGPTGVGKTELCKALANFMFD
                     SDEAMVRIDMSEFMEKHSVSRLVGAPPGYVGYEEGGYLTEAVRRRPYSVILLDEVEKA
                     HPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNLGSDLIQERFGELDYAHMKEL
                     VLGVVSHNFRPEFINRIDEVVVFHPLGEQHIASIAQIQLKRLYKRLEERGYEIHISDE
                     ALKLLSENGYDPVYGARPLKRAIQQQIENPLAQQILSGELVPGKVIRLEVNEDRIVAV
                     Q"
BASE COUNT         1374 a         1331 c         1516 g         1325 t
ORIGIN      
        1 gctcaagggc tgccgttttg cgtttataac acctgttaag tgttgctgct gttagcggca
       61 ataatttttg cgactttttc agcctgagcg ttcatctgca tctggcggta agcattttcc
      121 atcagcggca gcgcatcacg cgtagcttgg gtatccgggt agtcacgcag catgccttcg
      181 acgcggttga cgacggcaac ccatgcgcca cgttcggtgt agtactctgc aacggagtat
      241 tcatatttcg ccagacgatc tttcaggaac accagacgtt tggttgcatc agtggtgtat
      301 tggctgtttg gatagccgcg caccagtttg gaaaagtcac taaacgcagc tcgagcatgt
      361 tgaggatcgc gatcgctacg gtcaacgcca aagaaccctt gcagcgcact gtcatccagc
      421 gccatattgg tcaggccacg catgtacatg acataatcga tattcggatg ggtcgggttg
      481 aggcgaataa aacgatcgat ggcagcctgt gctaacggca gatcggcgtt tttatagtag
      541 gcgtagatga gatccagctg cacctgctgc gaatacggac caaacggata gcgattatct
      601 aacgcttcca gttgcgttat tgcctgtctc cagttaccgt cctgcagctt ttgttgtgca
      661 gtcgcgtaaa tttcatttgg cggattatca ggtacttctt cctttgaccc cgagcaaccc
      721 gccaaaaaca ggcttagtgt ggcggctgcc accagatatt tcatgcgcgt catgacgttt
      781 tgactttcct caaaatgtaa tacgggagat tctctgttcc tgctcccggt taagaccagc
      841 tacaatagca cactatatta aacggcaaag ccgtaaaacc ccaacgataa acgaagaagc
      901 agtatatatg gcacaacgag tacagctcac tgcaacggtg tccgaaaacc aactcggtca
      961 acgcttagat caggctttgg ccgaaatgtt cccggattat tcacgttcgc ggataaaaga
     1021 atggatcctc gaccagcgcg tgctggttaa cggcaaagtt tgtgataagc cgaaagaaaa
     1081 agtattgggt ggcgagcagg tggccatcaa cgctgagatt gaagaagaag cgcgttttga
     1141 accgcaggat atcccgctgg atatcgtcta tgaagatgac gatatcatcg tcattaataa
     1201 accgcgcgac ctggtggtac atcctggcgc gggtaacccg gatggcacgg tactgaatgc
     1261 attgcttcat tattatccgc ccattgccga tgtaccgcgt gcaggcatcg tccatcgtct
     1321 ggataaagac accactggcc tgatggttgt ggcaaaaacc gttccggctc agacgcgttt
     1381 agtcgaatct ttgcaaaggc gtgaaatgac tcgtgagtat gaagcggtgg caattggtca
     1441 tatgaccgct ggcggtacag tagatgaacc aatcagccgc cacccgacca aacgtaccca
     1501 tatggcggtg catccgatgg gcaaaccagc ggtgactcac tatcgcatca tggaacactt
     1561 ccgtgtgcac acgcgtctgc ggttgcgtct ggaaactgga cgtacgcacc agatccgcgt
     1621 gcatatggcc catatcactc atccgctggt gggcgatccg gtttatggtg gccgtccgcg
     1681 tccgccaaaa ggtgcttcgg aagcgtttat ctccacgctg cgtaaatttg accgccaggc
     1741 gcttcatgca accatgctgc gtctttatca cccgatctcc ggtatcgaaa tggaatggca
     1801 tgcgcctatt ccacaagata tggtggagct gattgaggtg atgcgcgccg atttcgaaga
     1861 gcataaagat gaagtggact ggttatgagt aagctgattg tcccgcagtg gccgctgcca
     1921 aaaggtgttg cggcctgtag ctctactcgt atcggcggcg tgagcttgcc cccgtatgac
     1981 tcgctcaacc tcggtgccca ttgtggcgat aacccggatc acgttgagga gaatcgcaag
     2041 cgactttttg ctgcgggcaa tttgccttct aaaccggtct ggcttgagca ggtacacggc
     2101 aaagatgtgc ttaagcttac tggcgaacct tatgcctcaa aacgagcaga tgcctcttat
     2161 agcaatacgc ccggcacggt ttgcgcagtg atgactgccg actgcctccc tgtgctgttt
     2221 tgcaatcgag cgggaacgga agtcgccgcc gctcatgctg gctggcgtgg actgtgcgca
     2281 ggcgtgctgg aagagacagt ttcctgtttt gctgataatc cagaaaatat tctcgcctgg
     2341 ttagggccgg caattggtcc acgcgcgttt gaagtggggg cggaggttcg cgaggcgttt
     2401 atggcagtag acgccgaagc gagtacagct ttcattcagc atggtgataa gtatctggcg
     2461 gacatttatc agcttgcccg gcagcgtctg gcgagcgttg gtgttgaaca aattttcggc
     2521 ggcgaccgtt gtacatatac ggaaaatgag actttcttct cttatcgtcg cgacaagacc
     2581 accggtcgta tggcaagttt catttggctg atataaccta aagaatcaag acgatccggt
     2641 acgcgtgatt ttcttttcac attaatctgg tcaataacct tgaataattg agggatgacc
     2701 tcatttaatc tccagtagca actttgatcc gttatgggag gagttatgcg tctggatcgt
     2761 cttactaata aattccagct tgctcttgcc gatgcccaat cacttgcact cgggcacgac
     2821 aaccaattca tcgaaccact tcatttaatg agcgccctgc tgaatcagga agggggttcg
     2881 gttagtcctt tattaacatc cgctggcata aatgctggcc agttgcgcac agatatcaat
     2941 caggcattaa atcgtttacc gcaggttgaa ggtactggtg gtgatgtcca gccatcacag
     3001 gatctggtgc gcgttcttaa tctttgcgac aagctggcgc aaaaacgtgg tgataacttt
     3061 atctcgtcag aactgttcgt tctggcggca cttgagtctc gcggcacgct ggccgacatc
     3121 ctgaaagcag caggggcgac caccgccaac attactcaag cgattgaaca aatgcgtgga
     3181 ggtgaaagcg tgaacgatca aggtgctgaa gaccaacgtc aggctttgaa aaaatatacc
     3241 atcgacctta ccgaacgagc cgaacagggt aaactcgatc cggtgattgg tcgtgatgaa
     3301 gaaattcgcc gtaccattca ggtgctgcaa cgtcgtacta aaaataaccc ggtactgatt
     3361 ggtgaaccag gcgtcggtaa gactgccatc gttgaaggtc tggcgcagcg tattatcaac
     3421 ggcgaagtgc ccgaagggtt gaaaggccgc cgcgtactgg cgctggatat gggcgcgctg
     3481 gtggctgggg cgaaatatcg cggtgagttt gaagaacgtt taaaaggcgt acttaacgat
     3541 cttgccaaac aggaaggcaa cgtcatcctg tttatcgacg aattacatac catggtcggc
     3601 gcgggtaaag ccgatggcgc aatggacgcc ggaaacatgc tgaaaccggc gctggcgcgt
     3661 ggtgaattgc actgcgtagg tgccacgacg cttgacgaat atcgccagta catcgaaaaa
     3721 gatgctgcgc tggaacgtcg tttccagaaa gtgtttgttg ccgagccttc tgttgaagat
     3781 accattgcga ttctacgtgg cctgaaagaa cgttacgagc tgcaccacca tgtgcaaatt
     3841 actgacccgg caattgttgc agcggcgacg ttgtctcatc gctacattgc tgaccgccag
     3901 ctgccagata aagccatcga cctgatcgat gaggcagcat ccagcattcg tatgcagatt
     3961 gactcaaaac cagaagaact cgaccgactc gatcgccgta tcatccagct caaactggaa
     4021 caacaggcgt taatgaaaga gtctgatgaa gccagtaaaa aacgtctgga tatgctcaac
     4081 gaagaactga gcgacaaaga acgtcagtac tccgagttag aagaagagtg gaaagcagag
     4141 aaagcatcgc tttctggtac gcagaccatt aaagcggaac tggaacaggc gaaaatcgct
     4201 attgaacagg ctcgccgtgt gggtgacctg gcgcggatgt ctgaactgca atacggcaaa
     4261 atcccggaac tggaaaagca actggaagcc gcaacgcagc tcgaaggcaa aactatgcgt
     4321 ctgttgcgta ataaagtgac cgatgccgaa attgctgaag tgctggcgcg ttggacgggg
     4381 attccggttt ctcgcatgat ggaaagcgag cgcgaaaaac tgctgcgtat ggagcaagaa
     4441 ctgcaccatc gcgttattgg tcagaacgaa gcggttgatg cggtatctaa cgctattcgt
     4501 cgtagccgtg cggggctggc ggatccaaat cgcccgattg gttcattcct gttcctcggc
     4561 ccaacgggtg tggggaaaac tgagctttgt aaggcgctgg cgaactttat gtttgatagc
     4621 gacgaggcga tggtccgtat cgatatgtcc gagtttatgg agaaacactc ggtgtctcgt
     4681 ctggttggtg cgcctccggg atatgtcggt tatgaagaag gtggctacct gaccgaagcg
     4741 gtgcgtcgtc gtccgtattc cgtcatcctg ctggatgaag tggaaaaagc gcatccggat
     4801 gtcttcaaca ttctgttgca ggtattggat gatgggcgtc tgactgacgg gcaggggaga
     4861 acggtcgact tccgtaatac ggttgtcatt atgacctcta acctcggttc cgatttgatt
     4921 caggaacgct tcggtgaact ggattatgcg cacatgaaag agctggtgct cggtgtggta
     4981 agccataact tccgtccgga attcattaac cgtatcgatg aagtggtggt cttccatccg
     5041 ctgggtgaac agcacattgc gtcgattgcg cagattcagt tgaaacgtct gtataaacgt
     5101 ctggaagaac gtggttatga aatccacatt tctgacgagg cgctgaaact gctgagcgag
     5161 aacggttacg atccggtcta tggtgcacgt cctctgaaac gtgcaattca gcagcagatc
     5221 gaaaacccgc tggcacagca aatactgtct ggtgaattgg ttccgggtaa agtgattcgc
     5281 ctggaagtta atgaagaccg gattgtcgcc gtccagtaaa tgataaaacg agcccttcgg
     5341 ggctcgtttt tgtctataag ttagacggga aagactatat ttaagatgtt ttgcctgaaa
     5401 aatgagcgaa cgataaagtt tttatatttt cctcttgtca ggccggaata actccctata
     5461 atgcgccacc actgacacgg aacaacggca agcacgccgc cgggtcagcg gggttctcct
     5521 gagaactccg gcagagaaag caaaaa
//
LOCUS       DADXDL010000163         5488 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.163, whole genome shotgun sequence.
ACCESSION   DADXDL010000163 DADXDL010000000
VERSION     DADXDL010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5488
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.163"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..128
                     /gene="cutA"
                     /locus_tag="IRB70_004618"
     CDS             <1..128
                     /gene="cutA"
                     /locus_tag="IRB70_004618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="divalent cation tolerance protein CutA"
                     /protein_id="HBC0634436.1"
                     /translation="ALQERLRQLHPYELPELLAVEAASGLPEYLQWLAAESRPVN"
     gene            133..1164
                     /locus_tag="IRB70_004619"
     CDS             133..1164
                     /locus_tag="IRB70_004619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein-disulfide reductase DsbD N-terminal
                     domain-containing protein"
                     /protein_id="HBC0634437.1"
                     /translation="MTASTIRLRRWLAGLALLLALPATSAVAQDFELPPVDEVFVLSA
                     QATAPDRIEVRWRIADGYYLYRHRTSVKADAAFTGATMALPKGKAYRDEFFGDVETYR
                     KELLGTLTGTPAAGASATTLTVKYQGCADAGVCYPPQTRTLKVALPGEAGAGGFGCKA
                     RGLHDYVVKNGSADHPNAEVKFALGDVVNTMIGCTNGETIMLCHDTSLPRPYSLGFRV
                     QGTEGLWMDVNKSIYLEGKSPQPHRWEPAEGWFAKYDHPLWKRYADLAAGAGHGGMDW
                     FVIHAFVEALKAKAPMPIDIYDALAWSAITPLSEQSIAEGNRTLDFPDFTRGQWRTRK
                     PIFALNDAY"
     gene            complement(1175..1813)
                     /locus_tag="IRB70_004620"
     CDS             complement(1175..1813)
                     /locus_tag="IRB70_004620"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HBC0634438.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVA
                     GALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKP
                     VWKALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALP
                     WGLAGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
     gene            complement(1818..2183)
                     /gene="ble"
                     /locus_tag="IRB70_004621"
     CDS             complement(1818..2183)
                     /gene="ble"
                     /locus_tag="IRB70_004621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bleomycin binding protein Ble-MBL"
                     /protein_id="HBC0634439.1"
                     /translation="MADHVTPNLPSRDFDVTEAFYAKLGFATSWKDRGWMILQRGGLQ
                     LEFFPYPDLDPATSSFGCCLRLDDLDAMVALVNAAGAEEKSTGWPRFKAPQLEASGLR
                     IGYLIDPDCTLVRLIQNPD"
     gene            complement(2187..2999)
                     /locus_tag="IRB70_004622"
     CDS             complement(2187..2999)
                     /locus_tag="IRB70_004622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="HBC0634440.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQ
                     RFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQIL
                     NWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHS
                     LTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSL
                     GNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
     gene            3198..4214
                     /locus_tag="IRB70_004623"
     CDS             3198..4214
                     /locus_tag="IRB70_004623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5-like element IS5 family transposase"
                     /protein_id="HBC0634441.1"
                     /translation="MFVIWSHGTGFIMSHQLTFADSEFSSKRRQTRKEIFLSRMEQIL
                     PWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLF
                     ARLSLDSALPDRTTIMNFRHLLEQHQLARQLFKTINRWLAEAGVMMTQGTLVDATIIE
                     APSSTKNKEQQRDPEMHQTKKGNQWHFGMKAHIGVDAKSGLTHSLVTTAANEHDLNQL
                     GNLLHGEEQFVSADAGYQGAPQREELAEVDVDWLIAERPGKVRTLKQHPRKNKTAINI
                     EYMKASIRAKVEHPFRIIKRQFGFVKARYKGLLKNDNQLAMLFTLANLFRADQMIRQW
                     ERSH"
     gene            complement(4323..5324)
                     /locus_tag="IRB70_004624"
     CDS             complement(4323..5324)
                     /locus_tag="IRB70_004624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_079376506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBC0634442.1"
                     /translation="MEYIKLSYHHLNFEDRTALMLESRKEGFSARKFAELIKRHPSTI
                     YRELKRNSINDVYQARYASDNTFARRRRGHRKLKIDSILWKFIVEAIRCLWSPQQIAK
                     RLKTFPDLDQTMNVSHTTIYSTIRALPKGELKKDLLSCLRHENKKRKANGEPKKDSIL
                     QDIKTIHERPAEVQERKIPGHWEADLIKGKDNKSSIATLIERNTRLCILATLPDAKAE
                     SVRKALTEALKYLPAELRKTLTYDRGREMSEHKILEEDLGIDVYFCDPHSPWQKGTCE
                     NMNGLIRQYLPKGIDLNQADQHYLNQVAMSLNTRPRKALDWLTPLGKVRISGEILLG"
BASE COUNT         1251 a         1552 c         1476 g         1209 t
ORIGIN      
        1 ccgccctgca ggaacgcctg cgccaactgc atccctacga actcccggag ctgctcgcgg
       61 tcgaagccgc gtccggcctg cccgaatacc tgcaatggct ggccgccgag agccgaccgg
      121 taaactgagc caatgaccgc atccacgatc cgcctgcgcc gctggctggc cgggctcgcc
      181 ctgctgcttg cgctgcccgc gacctcggcc gtcgcccagg acttcgaact gccgccggtc
      241 gacgaggtct tcgtcctgtc cgcgcaggcc accgcgccgg accgcatcga ggtgcgctgg
      301 cggatcgccg acggctatta cctgtaccgg caccgcacct cggtcaaggc cgatgccgcc
      361 ttcaccggcg cgaccatggc gctgccgaag ggcaaggcct accgcgacga attcttcggc
      421 gacgtcgaaa cctaccgcaa ggaattgctc ggcaccctca ccggcacgcc cgcggccggc
      481 gcgagcgcga ccaccctgac cgtgaagtac cagggctgcg ccgatgccgg cgtgtgctac
      541 ccgccgcaga cccgcaccct gaaggtcgcg ttgccgggcg aagcgggcgc tggcggcttc
      601 ggctgtaagg cgcgcgggct gcatgattat gtcgtcaaga acggctctgc cgatcatccc
      661 aacgccgagg tgaaattcgc actgggtgat gtggtcaaca ccatgatcgg ctgcactaat
      721 ggtgaaacga tcatgctgtg ccacgacacc tcgctgccgc gcccctattc tctcggcttt
      781 cgggtgcaag gcaccgaggg gctgtggatg gacgtcaaca agtcgatcta tctggagggc
      841 aagagcccac agccgcaccg ctgggagcct gccgagggct ggtttgcgaa atacgatcac
      901 ccgctatgga aacgctacgc cgatctggcg gcaggggccg ggcatggcgg gatggactgg
      961 ttcgtgatcc acgcttttgt cgaggcgctg aaggccaagg ccccgatgcc aatcgacatt
     1021 tacgacgcgc tggcctggag cgcgatcacg cctctgtcgg aacaatcgat tgctgagggc
     1081 aatcgcacgt tagattttcc cgacttcacc cgagggcagt ggcgcacccg caagccgatc
     1141 tttgcgctga acgacgccta ttgatcgacg cgatttaggc caagcgcacc gcaaaggcga
     1201 aattggtaat cttgtcggta tccttgacgc ccggcgcgct ttcgacgccg ctggaggtat
     1261 cgaccagcgg cgctccggtg cgcgcaatcg cctcggcaac attcgtcgga tttagcccgc
     1321 ctgccagccc ccacggcaag gcaccgcgat atccggccag cagcgaccag tcgaacgcca
     1381 accccatgcc gccgggcagc gcgcctttgg gggtcttggc gtcgaacaag atcaagtccg
     1441 ccgccccggc ataggctgcg gcgcgtgcga catcgctggc gctggcgacg ggcagcgcct
     1501 tccacaccgg cttgccaaac cgcgcgcgca actgggccac gcgttcgggc gattccgaac
     1561 cgtgcagctg cagcgcgttc agcttggctg ccaccagtgc gtcggcgatg acagcatcat
     1621 ccgcatcgac gaacaaaccg accatggcga tctggccagc tgcgcgcgat gtcaaagcgc
     1681 ccgcgacatt cgacgtaacc gcacggggcg acgctggata gaacaccaac ccggcatagt
     1741 ccgcccgcgc cgcgatggtc gcatcgagcg cctcgggtgt gctgatcccg caaatcttga
     1801 ttttcgcggg catgcggtca gtcggggttc tggatcagcc gcaccagcgt gcagtcggga
     1861 tcgatcaggt agccgatcct caggccgctc gcctccagtt gcggagcttt gaagcgcggc
     1921 cagccggtgc ttttttcctc ggctcccgcc gcgttcacca atgccaccat ggcatcgaga
     1981 tcatccaacc gcaggcaaca gccgaacgag ctcgtagctg ggtcgaggtc aggatagggg
     2041 aagaattcga gctgcaaacc gccgcgctgc aggatcatcc agccgcgatc cttccaactc
     2101 gtcgcaaagc ccagcttcgc ataaaacgcc tctgtcacat cgaaatcgcg cgatggcaga
     2161 ttgggggtga cgtggtcagc catggctcag cgcagcttgt cggccatgcg ggccgtatga
     2221 gtgattgcgg cgcggctatc gggggcggaa tggctcatca cgatcatgct ggccttgggg
     2281 aacgccgcac caaacgcgcg cgctgacgcg gcgtagtgct cagtgtcggc atcaccgaga
     2341 ttgccgagcg acttggcctt gctgtccttg atcaggcagc caccaaaagc gatgtcggtg
     2401 ccgtcgatcc caacggtgat attgtcactg gtgtggccgg ggccggggta aaataccttg
     2461 agcgggccaa agttgggcgc ggttgctggt tcgacccagc cattggcggc gaaagtcagg
     2521 ctgtgttgcg ccgcaaccag cccctcttgc ggggcaagct ggttcgacaa cgcattggca
     2581 taagtcgcaa tccccgccgc atgcagcgcg tccataccgc ccatcttgtc ctgatgcgcg
     2641 tgagtcacca ccgccagcgc gaccggcagg ttgatctcct gcttgatcca gttgaggatc
     2701 tgggcggtct ggtcatcggt ccaggcggta tcgaccaaca gcacgcggcc gccatccctg
     2761 acgatcaaac cgttggaagc gactgccccg aaacccggca tgtcgagata ggaagtgtgc
     2821 tgccagacat tcggtgcgag ctggcggaaa accagatcgc caaaccgttg gtcgccagtt
     2881 tccatttgct ggccaatcgt cgggcggatt tcaccgggca tgcacccgct cagcatcaat
     2941 gcagcggcta atgcggtgct cagcttcgcg accgggtgca taatattggg caattccatc
     3001 aagttttcct tttattcagc attaaaaacc ccgcaaatgc gaggcctagt aaatagatga
     3061 tcttaatttg gttcactgta gcaaaaatat ggggcgaatt caaacatgag gtgcgacagt
     3121 ttcaaaagcc atatgataat caacaagctg agcaaatttc tctaaggaag gtgcgaacaa
     3181 gtccctgata tgagatcatg tttgtcatct ggagccatgg aacagggttc atcatgagtc
     3241 atcaacttac cttcgccgac agtgaattca gcagtaagcg ccgtcagacc agaaaagaga
     3301 ttttcttgtc ccgcatggag cagattctgc catggcaaaa catggtggaa gtcatcgagc
     3361 cgttttaccc caaggctggt aatggccggc gaccttatcc gctggaaacc atgctacgca
     3421 ttcactgcat gcagcattgg tacaacctga gcgatggcgc gatggaagat gctctgtacg
     3481 aaatcgcctc catgcgtctg tttgcccggt tatccctgga tagcgccttg cctgaccgca
     3541 ccaccatcat gaatttccgc cacctgctgg agcagcatca actggcccgc caattgttca
     3601 agaccatcaa tcgctggctg gccgaagcag gcgtcatgat gactcaaggc accttggtcg
     3661 atgccaccat cattgaggca cccagctcga ccaagaacaa agagcagcaa cgcgatccgg
     3721 agatgcatca gaccaagaaa ggcaatcaat ggcactttgg catgaaggcc cacattggtg
     3781 tcgatgccaa gagtggcctg acccacagcc tagtcaccac cgcggccaac gagcatgacc
     3841 tcaatcagct gggtaatctg ctgcatggag aggagcaatt tgtctcagcc gatgccggct
     3901 accaaggggc gccacagcgc gaggagctgg ccgaggtgga tgtggactgg ctgatcgccg
     3961 agcgccccgg caaggtaaga accttgaaac agcatccacg caagaacaaa acggccatca
     4021 acatcgaata catgaaagcc agcatccggg ccaaggtgga gcacccattt cgcatcatca
     4081 agcgacagtt cggcttcgtg aaagccagat acaaggggtt gctgaaaaac gataaccaac
     4141 tggcgatgtt attcacgctg gccaacctgt ttcgggcgga ccaaatgata cgtcagtggg
     4201 agagatctca ctaaaaactg gggataacgc cttaaatggc gaagaaacgg tctaaatagg
     4261 ctgattcaag gcatttacgg gagaaaaaat cggctcaaac atgaagaaat gaaatgactg
     4321 agtcagccga gaagaatttc cccgcttatt cgcaccttcc ctaatggtgt aagccaatct
     4381 aacgcctttc taggacgagt attcagtgac atggcaactt gatttaaata atgctgatct
     4441 gcctgattta aatcaatccc tttaggtaaa tattgcctaa ttaaaccatt catattttcg
     4501 catgtgcctt tttgccaggg tgaatgtggg tcacagaaat atacatctat gcctaaatct
     4561 tcttcgagta ttttatgttc tgacatctca cgtccacggt cataggtcaa cgttttacgc
     4621 agttctgcag gtaaatattt cagagcttca gttaaagcct tgcgcactga ttctgccttt
     4681 gcatcaggta atgttgccaa gatacagagc cgtgtatttc gttcaataag tgttgctatc
     4741 gaacttttat tgtctttacc tttaattaaa tcagcttccc aatgacccgg tatttttctt
     4801 tcttgaactt cggctgggcg ctcatgaata gttttaatat cctgtaatat agaatctttt
     4861 ttaggttcac cgttagcttt tcgcttttta ttttcatgac gtagacagga taataagtct
     4921 tttttcaact caccctttgg taatgctcgt atcgttgaat aaatcgttgt atggcttaca
     4981 ttcattgttt gatccaaatc aggaaatgtc tttaaacgct ttgctatttg ctgaggagac
     5041 cataaacaac ggatcgcttc aacaataaat ttccagagga ttgaatcgat tttgagtttt
     5101 ctgtgaccac gtctacgtct agcgaaggtg ttatcagaag catatcgagc ttgataaacg
     5161 tcattgatgc tatttctttt aagctcacga tagatcgtac taggatgtct tttaatgagt
     5221 tcagcaaatt ttctggctga aaagccttct tttcttgact caagcattaa tgcagtacga
     5281 tcttcaaagt taagatgatg gtatgacaat tttatatact ccataaaccc tttaaattaa
     5341 ttaggtggtt tatgtcgcac ttcaagtttt actctgccaa ctttaaatca gtggctccac
     5401 taacactctt cacttattta tttaaaattt agcgacgtta aaagacaatt aagtattttt
     5461 agataatggg gttctaggga ttttccgt
//
LOCUS       DADXDL010000164         5453 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.164, whole genome shotgun sequence.
ACCESSION   DADXDL010000164 DADXDL010000000
VERSION     DADXDL010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5453)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5453)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5453
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.164"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1035
                     /locus_tag="IRB70_004625"
     CDS             <1..1035
                     /locus_tag="IRB70_004625"
                     /inference="COORDINATES: protein motif:HMM:NF015354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HBC0634443.1"
                     /translation="KKKGISDSVILIPQEADQRFLKPEYLWNTIEKSEKRKDAQLARE
                     FNIALPVEMTDEQKKALAIDFCNENFVKNGMIADIAFHKLDSDNPHFHVMLTTRKLTP
                     DGSGFGQKVREWNSKEQLQEWRKSWADTANEHLQAAGIDARIDHRSLKDQKAELDAIP
                     SPTAEQQAQAISLDRPPTIHRGHSGNRERLERFDALQEVKASQEAKALNHIEINTLKP
                     SPPAPASSPAASSMDAKQGGKKAASTGSAAATVSGSNINLVDETTDKNLHLTEAQREE
                     LEDAENKEAAAKKKAYLSGGAGVPDFSETNKIQSKSEFKNRFNKMKNAINKEDEEEEN
                     TYKINRPKLK"
     gene            complement(1052..2743)
                     /locus_tag="IRB70_004626"
     CDS             complement(1052..2743)
                     /locus_tag="IRB70_004626"
                     /inference="COORDINATES: protein motif:HMM:NF013603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBC0634444.1"
                     /translation="MLSEERLSAIRAKVNRANSSQNKKSATLSSVSTNGDRITERKKE
                     SFKTANSFIIRGKIEENETLTKRGERSLNCAQQRYIVVVNGKAHTVFTHRCRSRHCQN
                     CQRIKAFVWQEKMKEIFPDLISKYPNHKYLFITFTVKNPKLKNLKSVLICMSRAYAKM
                     FQRKAFKKWFVGDIRSTEITRGNSGDDEAHPHFHALICVHPTYFKGANYMSADVWGQN
                     WGECLESEFKKEGLEYNASDYPKGFPRVDIRLAKSADRKTDITNQNISEHGEQLINYV
                     LKYSVKGSDLLKNGKADAWFWEFDKQVKNIRMIAASGDIKKSLAKLERDQFDYYKEQE
                     KIEKLISDDVNFKADKAVFKKEDEYNYYLESKKDKFQYIIEAIEAKAYNYQCYYKALL
                     SDHLLAFRSGIDGIIENFRKINKTKTREDFEILEAAEQELVKIQCERIERLRFICDAL
                     VRVGLYKKMSDFVYMNIHTNEKTVIVKNNIVDILKAAEQKLLNDFKQSFMRLESAKTQ
                     DVFNAIVDKVNEKSALIKLVRNEILAAGAYAYDADSLEYIDLETNERLEVIATIE"
     gene            complement(3541..4005)
                     /locus_tag="IRB70_004627"
     CDS             complement(3541..4005)
                     /locus_tag="IRB70_004627"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634445.1"
                     /translation="MADMYYLICGLFIAIFFIACLLSVIYAAEIYQWQHYNAYKFKRW
                     LKSGSIKKDEEQEKIKREVKKMTIDNILRLLKKYKIDFDANELVKNDFNIKMKYYKLI
                     LAEKERLKENKRLDEELKQKIKIETDTFDAEKFQKEAEERFKIFMKNRNKNK"
     gene            complement(3998..4243)
                     /locus_tag="IRB70_004628"
     CDS             complement(3998..4243)
                     /locus_tag="IRB70_004628"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634446.1"
                     /translation="MNIMGFLGFVAKAKPDVDDGGGSLIPAAMGFFIVAFFVAIIASV
                     VSSAFRSAKNSADVSINNAKKYHVALIKEQYRKKGGG"
     gene            complement(4240..4650)
                     /locus_tag="IRB70_004629"
     CDS             complement(4240..4650)
                     /locus_tag="IRB70_004629"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634447.1"
                     /translation="MNNIRPNPNPKKEGTADMMNRLNFYDTSFACLHFLMIDFDNDMQ
                     EMKRKKDFHPLMLLNKHDRASIDLEILNIIRISLASKMLDIQSEELLGADLYFNKRDE
                     LDMGEDARIIGYVFRDFVKQRIETAIKNMEDKNI"
     gene            complement(4643..4984)
                     /locus_tag="IRB70_004630"
     CDS             complement(4643..4984)
                     /locus_tag="IRB70_004630"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634448.1"
                     /translation="MAFNIEKYNKVKKELEQKANLLNRMEQEMKAEKRKEDAARKIKV
                     GAELIRIVRENNIETLDFASDISLLVGALTNNLILKRIHDQREFLRVEGDKRLNEWKL
                     KNNKKRSKTNE"
     gene            5340..>5453
                     /locus_tag="IRB70_004631"
     CDS             5340..>5453
                     /locus_tag="IRB70_004631"
                     /inference="COORDINATES: protein motif:HMM:NF015354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HBC0634449.1"
                     /translation="MSAQTISRSKGHSSVAAAAYRHGEKLMDEHTGEIHDYS"
BASE COUNT         1631 a         1146 c          910 g         1766 t
ORIGIN      
        1 aaaaaaaaag gtatttcaga cagtgtgata ttaataccac aagaagcaga tcaaagattt
       61 ttaaaacctg aatacttgtg gaacactatc gaaaaaagcg agaaaagaaa agatgcgcag
      121 ttagcacgcg agtttaatat tgcgctcccc gtagaaatga cagacgaaca aaaaaaagca
      181 ttagcaatag atttctgtaa tgagaacttt gtaaaaaatg gaatgattgc ggatatagct
      241 tttcataagc tcgatagcga caacccacat tttcacgtaa tgctaacgac aagaaagcta
      301 accccggacg gctccgggtt cgggcaaaag gtcagagaat ggaacagcaa agagcagctg
      361 caggaatggc gtaagagctg ggcagacaca gcgaacgagc acctgcaggc cgctggcatc
      421 gatgcgcgta ttgatcaccg ttcactgaaa gaccaaaaag cagagcttga cgctatcccc
      481 tcccccaccg cggagcaaca ggcgcaggct atcagcttag acagaccgcc aaccatacac
      541 agggggcaca gcggcaacag ggagcgttta gaacgctttg acgcgcttca agaagtgaaa
      601 gcgtcacaag aagctaaagc acttaaccac attgaaataa acacgcttaa gccctcgcct
      661 ccggctcctg cttcctcccc tgccgcgtct tctatggacg ctaaacaggg aggcaaaaaa
      721 gcagcttcaa caggttcagc agcggctaca gtttcaggat ctaatatcaa tctcgtagat
      781 gaaacaacag acaaaaatct acacctaacg gaagcgcagc gcgaagagtt agaagacgca
      841 gaaaataaag aagcggcagc caagaaaaaa gcatacctca gcggcggcgc tggcgttcct
      901 gactttagcg aaacaaacaa aatacagtct aaaagtgagt ttaaaaatag atttaacaaa
      961 atgaaaaatg cgattaataa agaagatgaa gaagaagaaa acacctacaa aataaataga
     1021 ccaaaactaa aataatagct cgcaagagct attattctat agtcgctata acttctaaac
     1081 gctcgttagt ttcaagatct atatattcga gactatcagc atcataagca tacgcgccag
     1141 cggctaaaat ctcatttctt acaagtttaa tcagtgctga tttttcattt actttatcca
     1201 caatagcatt aaatacatct tgggtttttg cgctttcaag tctcatgaaa ctttgcttaa
     1261 aatcgtttaa aagtttttgt tctgctgctt tcaaaatatc tacgatgtta ttttttacaa
     1321 taacagtttt ttcatttgta tgtatattca tatacacaaa atcagacatc tttttatata
     1381 agccgactct tacaagcgca tcacaaataa agcgcaagcg ttctattctt tcgcattgta
     1441 tttttacaag ctcctgttct gctgcttcta atatttcaaa atcttctctc gtttttgttt
     1501 tatttatttt gcgaaagttt tcaatgatgc catcaatacc gcttctaaac gctaaaagat
     1561 gatcagataa taacgcttta taatagcatt gatagttata cgctttagct tcaatcgctt
     1621 caatgatata ttgaaactta tcttttttac tttctaaata atagttgtat tcatcttctt
     1681 ttttaaatac tgctttatct gctttaaagt tcacatcatc agatattagt ttttctatct
     1741 tttcttgttc tttataataa tcaaactgat cgcgttcaag tttagcgagt gattttttaa
     1801 tatcgccgct tgccgcaatc attctaatat tttttacttg cttatcgaac tcccagaacc
     1861 aagcatcagc ctttccgttc ttgagcaagt ccgaaccttt gacgctatat tttaaaacgt
     1921 agtttataag ctgctcgccg tgttcgctga tattttgatt agtaatatct gttttcctat
     1981 cagcagattt agcaaggcga atatcaacac gcggaaaacc cttaggataa tcagaagcgt
     2041 tatattctaa tccttccttt ttgaattcag attctaagca ctcgccccag ttttggcccc
     2101 atacgtctgc gctcatatag ttcgcacctt taaaatatgt aggatggaca caaataagcg
     2161 cgtgaaaatg cgggtgcgct tcatcatctc cgctatttcc tcgcgtgatt tctgtcgatc
     2221 taatatcacc cacaaaccat tttttaaacg ctttacgttg aaacatttta gcgtaagcgc
     2281 gagacataca aatcaataca gatttaagat tttttaactt cggattttta actgtaaatg
     2341 taataaacaa gtatttgtga tttggatatt tagaaatgag atcgggaaat atctctttca
     2401 ttttttcttg ccatacaaaa gcctttattc tctggcagtt ttggcaatga cgagagcggc
     2461 agcgatgagt aaatacagtg tgcgctttac cattcacaac gacaatataa cgctgttgcg
     2521 cacagtttaa agaacgttcg ccgcgttttg ttagcgtttc attttcttca atcttgccgc
     2581 gaataataaa actattggca gtcttaaaac tttctttttt gcgttctgtg attcgatcac
     2641 catttgtaga aacgcttgaa agtgttgcac tttttttatt ttgtgagcta ttagctctat
     2701 tgacttttgc gcgtatagcg cttaatcttt cctctgaaag catataaaaa accccttatt
     2761 gtatggaacc gtcgcaagtt caactctaag gggtttttta tttctgtcaa tcacttacac
     2821 ccgctttgca tacaaatcga acacctcagc cgcccatccc gaacacctaa aaccgcccaa
     2881 aagtgcagac ctgtcccatt tttgcgccca ttttccgccg ctccgctttc cctcatccca
     2941 aaaagcaggg ataaaaaggc ggttttaggt ggtgtcatcc caccttcagc cgtttatccg
     3001 aaaccttttg cagatcacat cccaacacag gagaggaaag ggcgatttta tgcagacccg
     3061 tcccattttc agcaggaacc cgtgcgagta ttttttggtt aaaaaatggg cgttttagct
     3121 accgccattg accaatagat tttcgagcaa agccatacac accaaggctt acaggccgat
     3181 ttttggggtt aaaaaaatct gatttgtttc ttattaaaca agggaagcag gtcactcgct
     3241 tcgctcactc ccaaaaccca aaaccaaagg gcaagggcgg ggcgtcaaat gccccctgac
     3301 tcagctgcag ggctggcact cccaccactt aacaaaccca cccggaacgg caggaggcca
     3361 gcggccagag attaccacag agagggacgg taaagggctt aaaggcggct taacaggcga
     3421 aaggctcgcc ttgctctcct ttcaccatga caagtttttt ttatctggtg agttgtcaat
     3481 aaaaataaag gtatccaccc tacgggcgga acctccttga ttttttttga caagttgagg
     3541 ttatttattt ttattacgat ttttcatgaa tattttaaat cgttcttctg cttctttctg
     3601 aaacttttca gcgtcaaacg tatcagtttc tatttttatt ttttgtttta actcttcatc
     3661 taatctttta ttttctttca gtctttcttt ctctgctaat ataagcttgt aatatttcat
     3721 tttaatatta aaatcatttt tcactaactc gttagcgtca aaatctattt tgtatttctt
     3781 gaggagtctt aaaatattat ctatagtcat tttctttact tcccttttta ttttttcttg
     3841 ctcctcatct ttttttatac ttccactttt caaccagcgt ttaaacttgt aagcgttgta
     3901 atgctgccac tgatatattt cagcggcata tataacggaa agcagacagg caataaaaaa
     3961 tatagctata aatagaccac atattaaata atacatatca gccaccgcct ttttttctat
     4021 attgctcttt tattagtgct acgtgatatt tttttgcatt attaatactc acgtctgccg
     4081 agtttttagc agaacgaaaa gcacttgaaa caactgacgc aatgatagca acaaaaaaag
     4141 caacaataaa aaaccccata gcggcgggaa taagacttcc gccgccatca tccacgtcag
     4201 gttttgcttt tgctacaaaa cccaaaaaac ccattatatt catatatttt tatcctccat
     4261 gtttttaatc gctgtttcta ttctttgttt tacaaagtct ctaaatacat aaccgattat
     4321 tctcgcatct tcgcccatat ctaactcatc tcttttatta aaatataaat cagcgcccaa
     4381 aagttcctcg ctttgaatat ctaacatttt gctagcaagt gatattctaa taatatttaa
     4441 tatctctaaa tcaatgctcg ctctatcgtg tttattcaaa agcatcagtg ggtgaaaatc
     4501 tttttttctt ttcatttctt gcatgtcatt atcaaaatct atcattagaa aatgcaaaca
     4561 agcaaaagac gtatcataga agtttaagcg gttcatcatg tccgccgttc cctctttttt
     4621 agggttcggg ttaggtctta tgttattcat tcgtcttgct cctttttttg ttgtttttta
     4681 acttccactc gttaagtctt ttatcgccct caactctcaa aaactcgcgt tgatcgtgta
     4741 ttctttttaa tattaggtta ttagttaaag cgccaaccaa taaagaaata tcgctagcaa
     4801 aatctaatgt ctctatatta ttttctctaa ctatccttat tagttcagcg ccaactttta
     4861 ttttacgcgc tgcgtcctct tttctttttt cagctttcat ttcttgctcc atacgattta
     4921 ataagtttgc tttttgctca agctcttttt ttactttatt atatttttct atattaaatg
     4981 ccatgtttca cctcttttat tttttgcgat ttctgttata tatattttag gtaatatatt
     5041 tatttattta agtaaagcgc gatatatgta ttttttattt tccgagcgcg attttataga
     5101 taaaaggttt acgtgcagcg gctattttag ttttgctaaa aactacaata gcgcacttat
     5161 acattcttcg aatgtgtgcg ccccataaat ggggatttac tgcaatcaaa aaataataat
     5221 gaatactcgc tttatgctca tattacatta ttgatttttg ataatgcaaa aatagtttta
     5281 cttatttttt atgtatgtgc tttcaatatc aggagataaa aacaatggca atatttcata
     5341 tgagcgctca aacaataagc cgctcaaaag gacatagtag cgtagctgcg gcggcatatc
     5401 gccacggtga aaagttaatg gacgaacaca caggagagat ccacgactac agc
//
LOCUS       DADXDL010000165         5449 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.165, whole genome shotgun sequence.
ACCESSION   DADXDL010000165 DADXDL010000000
VERSION     DADXDL010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5449)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5449)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5449
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.165"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            57..1136
                     /locus_tag="IRB70_004632"
     CDS             57..1136
                     /locus_tag="IRB70_004632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000061479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction enzyme HsdR N-terminal
                     domain-containing protein"
                     /protein_id="HBC0634450.1"
                     /translation="MSMEFIDKLNSLSAKIKQQAGVIETEEATKNAFVMPFINNVLGY
                     DVFDPTEVIPEFVCDIGTKKGEKIDYAILKNSEVQILIECKKIGDPLNINHASQLFRY
                     FHVTNARISILTNGQVYKFFTDLEAPNKMDEKPFLEIDLLDLDETVVPEIKKLTKSAF
                     DLESIINAAGELKYVSLIKKVLHAQMNNPEEDFVKFFAARIYEGMLTQKVKDTFAKLT
                     KKAANQYINSQINERLKSAIGGGSLSVIDSNSHNEEVECINKEETDIATTMEELEGFH
                     IVKAIVRVVLDAPRIVHRDTKSYFGILVDDNNRKPLCRLHFNRNQKYIGLFDLEKNET
                     RHPIESLDDIYSFSDELKATAALYN"
     gene            complement(1177..2715)
                     /gene="aldB"
                     /locus_tag="IRB70_004633"
     CDS             complement(1177..2715)
                     /gene="aldB"
                     /locus_tag="IRB70_004633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001551836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldehyde dehydrogenase AldB"
                     /protein_id="HBC0634451.1"
                     /translation="MTNNPPSAQIKPGEYGFPLKLKARYDNFIGGEWVAPADGEYYQN
                     LTPVTGQLLCEVASSGKRDIDLALDAAHKVKDKWAHTSVQDRAAILFKIADRMEQNLE
                     LLATAETWDNGKPIRETSAADVPLAIDHFRYFASCIRAQEGGISEVDSETVAYHFHEP
                     LGVVGQIIPWNFPLLMASWKMAPALAAGNCVVLKPARLTPLSVLLLMEIVGDLLPPGV
                     VNVVNGAGGEIGEYLATSKRIAKVAFTGSTEVGQQIMQYATQNIIPVTLELGGKSPNI
                     FFADVMDEEDAFFDKALEGFALFAFNQGEVCTCPSRALVQESIYERFMERAIRRVESI
                     RSGNPLDSVTQMGAQVSHGQLETILNYIDIGKKEGADVLTGGRRKLLEGELKDGYYLE
                     PTILFGQNNMRVFQEEIFGPVLAVTTFKTMDEALELANDTQYGLGAGVWSRNGNLAYK
                     MGRGIQAGRVWTNCYHAYPAHAAFGGYKQSGIGRETHKMMLEHYQQTKCLLVSYSDKP
                     LGLF"
     gene            complement(2823..4118)
                     /locus_tag="IRB70_004634"
     CDS             complement(2823..4118)
                     /locus_tag="IRB70_004634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fic family protein"
                     /protein_id="HBC0634452.1"
                     /translation="MAIKSPPGLIPLSHLSGEELLAHLRFNRVTDEKGRYLPFDELQY
                     RIKKGENVDVAWTLTRLARNAAIQRINYCNEAGEQAGFNITPVIAEACELVDKRATAL
                     ALKDQTERLRGAGAELSQLRLEEPITSSQLEGANTTTLVARKMLETGRSPRTEDEHMI
                     AGNARLMAEIPHLLAEPLTPALIRQLHAIGMGGINDAKYRPGEFRETDDVVIADYDGN
                     IVHQPPAAALLPERLEKVCQWLNSHEGYIHPLVRACILHFMLAHEHPFRDGNGRTSRA
                     LFYWYMLKSGYDVFKYISISRLLHAAPVKYAASYQYTESDGMDLTYFLEYQAGVIKRA
                     LQNWQQHIDEITQRSAKLDSVLFSSGVLKRLNPRQVTLLNVMLANPGKEYTVAEISAS
                     LGVSDNTARADLRTIVKEGFAQEKKINDQQAVYFAHYPL"
     gene            complement(4248..5399)
                     /gene="yiaY"
                     /locus_tag="IRB70_004635"
     CDS             complement(4248..5399)
                     /gene="yiaY"
                     /locus_tag="IRB70_004635"
                     /EC_number="1.1.1.103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine dehydrogenase"
                     /protein_id="HBC0634453.1"
                     /translation="MAASTFFIPSVNVIGADSLNDAMNMMADYGFTRTLIVTDNMLTK
                     LGMAGDVQKALEERNIFSVIYDGTQPNPTTENVAAGLKLLKENNCDSVISLGGGSPHD
                     CAKGIALVAANGGDIRDYEGVDRSAKPQLPMIAINTTAGTASEMTRFCIITDEARHIK
                     MAIVDKHVTPLLSVNDSSLMIGMPKSLTAATGMDALTHAIEAYVSIAATPITDACALK
                     AVTMIAENLPLAVEDGSNAKAREAMAYAQFLAGMAFNNASLGYVHAMAHQLGGFYNLP
                     HGVCNAVLLPHVQVFNSKVAAARLRDCAAAMGVNVTGKNDAEGAEACINAIRELAKKV
                     DIPAGLRDLNVKEEDFAVLATNALKDACGFTNPIQATHEEIVAIYRAAM"
BASE COUNT         1456 a         1339 c         1254 g         1400 t
ORIGIN      
        1 attttctata tttttataaa acgcattttt attaaatata tataaaagga gttataatgt
       61 ctatggagtt tatagataag ctgaattcat tatccgcaaa aataaaacaa caagccggag
      121 tcattgaaac ggaggaagct accaaaaatg ctttcgtaat gccgttcatt aacaatgtgt
      181 taggttatga tgtctttgat cctaccgaag ttatcccaga gtttgtatgc gacattggaa
      241 cgaagaaagg tgaaaagatt gactatgcaa tcttaaaaaa tagcgaggtt caaattctca
      301 ttgaatgcaa aaaaattggc gatcctctaa atataaatca tgcttcacag ctttttcgat
      361 actttcatgt aacaaatgca agaatatcta ttctaaccaa tggacaagtt tataaatttt
      421 ttactgattt agaagcacct aataaaatgg atgaaaaacc atttcttgag atagatctac
      481 ttgacttaga tgaaacagtt gttcccgaga taaagaagct tactaaatca gcatttgatt
      541 tggaatcaat aattaatgct gcaggtgaat taaaatatgt tagtttaatt aaaaaagttc
      601 tccatgcaca aatgaataat cctgaagagg attttgtaaa attctttgca gcaagaattt
      661 atgaaggtat gttaacacaa aaggtaaaag atacgtttgc aaaattaaca aagaaagctg
      721 ccaatcaata tattaactct caaataaacg aaagattgaa atcggcaata ggtggtgggt
      781 cattatctgt aattgattcg aattcacaca atgaggaagt agaatgtatt aataaagaag
      841 aaaccgatat tgccactact atggaggaac ttgaaggatt tcatattgtt aaagctatag
      901 tccgcgtagt gcttgatgca ccacgaatag tccacagaga tacaaaaagc tattttggta
      961 tacttgtaga tgacaataat cgaaagccac tctgtagatt acatttcaat cgaaatcaaa
     1021 aatatattgg tttatttgac ttagagaaaa acgaaacccg ccatcctatt gaatctctcg
     1081 atgatattta ttctttcagc gatgagttaa aagcgactgc cgctttatac aactaaaaca
     1141 aaggcagaca actattaacg ttgcctgcct ttcacatcag aacagcccca acggtttatc
     1201 cgagtagctc accagcaggc acttggtttg ctggtaatgc tcaagcatca tcttatgggt
     1261 ttcgcgtccg atgcccgact gtttgtagcc gccaaacgcc gcatgtgccg ggtaagcgtg
     1321 ataacagttg gtccacacgc gcccggcctg aatgccgcgc cccatcttat aggccagatt
     1381 accgttgcgg ctccagacac ccgcgcccag gccatattgc gtgtcgttcg ccagctccag
     1441 cgcctcgtcc atcgttttga aggtggttac cgccagcacc ggaccaaaaa tctcctcctg
     1501 gaacacgcgc atattattct gaccaaacaa aatcgtcggt tcgaggtagt aaccgtcttt
     1561 cagttcgcct tccagcagct tgcgccgccc gccggtgagc acgtctgcgc cctctttttt
     1621 accaatatca atgtagttga ggatggtttc cagttgcccg tgagaaacct gcgcccccat
     1681 ttgcgtcacg ctgtcgagcg ggttaccgct gcgaatgctt tcgacacggc ggatggcgcg
     1741 ttccataaag cgttcgtaga tagactcctg cactaaagca cggcttggac aggtgcaaac
     1801 ttcgccctgg ttaaaggcaa acagtgcaaa gccttccagc gctttatcga aaaaggcatc
     1861 ttcttcatcc atcacatcag caaagaagat atttggggat ttgccgccca gctccagcgt
     1921 caccggaata atgttttgcg tggcgtactg cataatttgt tggcccactt ccgttgagcc
     1981 ggtaaacgcc actttggcga tgcgtttcga ggtcgccaga tattcgccaa tttctccgcc
     2041 cgcaccgttg accacgttca ccacgcccgg cggcagtaaa tcaccgacga tttccattag
     2101 cagcagtact gagagcgggg taagacgtgc gggtttcagc accacacagt tgcccgccgc
     2161 cagcgcggga gccattttcc agctcgccat cagcagcggg aagttccacg gaataatctg
     2221 ccccaccacg cctaacggtt cgtggaagtg ataagccaca gtttcgctat ccacttcact
     2281 aataccgcct tcctgcgccc gaatacacga ggcaaaatag cgaaaatggt caatcgccag
     2341 cggcacatca gcagcactgg tttcgcgaat gggtttgccg ttatcccagg tttcagcggt
     2401 cgctaacagt tcgaggttct gctccatccg atcggcaatc ttaaacagaa tcgccgcgcg
     2461 atcctgcacc gaagtatgcg cccatttatc tttcactttg tgcgcagcat ccagcgccag
     2521 atcgatgtct cgtttgcccg aagacgccac ttcgcacagc agctgtccgg tcaccggcgt
     2581 caggttctgg taatactcgc cgtcggcagg ggctacccat tcgccgccaa taaagttgtc
     2641 gtagcgggct tttaacttga gggggaaacc atactcgccg ggcttaatct gtgctgaagg
     2701 gggattattg gtcatgatcg tctccttgcg gtgtgaggta taacaagggt agacgtgact
     2761 ggcgaaatct tcgccagtcg ataacagctt tacgacggct atcacgaatt tacgggcaag
     2821 ggttacagcg gataatgcgc gaagtacacg gcttgctggt cattaatttt cttctcttgc
     2881 gcaaaccctt ctttaacaat tgtccgtaaa tcagctcgag ccgtattatc agagacgccc
     2941 aggctcgcgc taatttcagc aactgtgtac tctttccccg gattggcgag catcacattc
     3001 aggagcgtta cctggcgcgg attcaggcgt ttaagcacac cagagctaaa cagcacacta
     3061 tcgagttttg cgcttcgttg tgtaatttca tcgatatgct gctgccagtt ttgcagagca
     3121 cgtttaatga cacccgcctg atattcaagg aaataagtca gatccatacc atctgattca
     3181 gtgtactggt agctggcggc atatttgacc ggtgcagcat gaagcaaacg gctgatggaa
     3241 atatatttaa agacatcgta gcccgatttc agcatatacc agtaaaacag cgcccgactg
     3301 gtgcgcccgt tgccatcccg aaacggatgt tcatgggcca gcataaaatg cagaatgcag
     3361 gcacggacca acggatgaat atacccttca tggctgttta accactggca aactttttcc
     3421 agccgttccg gtaacaatgc cgcagcgggc ggttgatgca ctatattgcc atcatagtcg
     3481 gcgatcacaa catcatctgt ttcacgaaat tctcccggac gatatttcgc gtcattgatt
     3541 ccacccatac caatggcatg taactggcga ataagcgcag gtgtcagcgg ttctgcgagt
     3601 aagtgcggaa tttccgccat cagccgggca tttcccgcaa tcatatgctc atcttcagtg
     3661 cgtggcgacc gccctgtttc cagcattttt ctcgccacca gcgttgtagt attcgcacct
     3721 tccagctggg agctggtgat cggctcttcc aggcgtaact ggcttaactc ggctccggcc
     3781 ccgcgtaacc gttcagtctg atctttcagc gccagcgcgg tagcacgttt gtcgacaagc
     3841 tcgcacgctt ctgcaatcac cggggtaatg ttgaatccgg cctgttcacc cgcttcattg
     3901 caataattaa ttcgttggat cgccgcgttg cgcgccagac gggtaagcgt ccacgccaca
     3961 tcgacgtttt ctcctttttt gatgcggtac tgcaactcat caaaaggcag ataacgtcct
     4021 ttttcatcgg taacccggtt aaagcgcagg tgggccagga gttcctcacc cgataagtgt
     4081 gataaaggaa taagtccggg aggtgatttg atagccatgt gcttatctca aaaaagcgca
     4141 atattgagat agtatatagc aggaaagaga aactatctca aaaaaagcaa gttttgagat
     4201 agttgaaaaa gcggctgaca actcgccagc cgttgcggga atgatgatta cattgcggcg
     4261 cgataaatcg ccacaatttc ttcgtgagtt gcctggatcg ggttagtaaa gccacaggca
     4321 tctttcaggg cattagtcgc cagtaccgcg aaatcttctt ctttcacgtt caggtcacgc
     4381 aggcctgccg ggatatccac tttcttcgcc agttcacgga tggcgttaat gcaggcttca
     4441 gcaccttccg cgtcgttttt accagtcacg ttcacgccca ttgcagcggc acagtcacgc
     4501 agacgtgctg cagcgacttt gctattgaat acctgaacgt gtggcagcag aacagcatta
     4561 catacaccgt gtggcaggtt gtagaaaccg cccagctggt gcgccatcgc atgaacataa
     4621 cccagagaag cattattgaa cgccataccg gcgaggaact gggcataagc cattgcttca
     4681 cgcgctttag cattgctgcc atcttcaacg gctaacggca gattttcggc aatcatggtc
     4741 accgctttca gtgcgcaagc gtcagtgatc ggcgtggcgg caatagaaac atacgcttcg
     4801 atagcgtgcg ttaaggcatc catacccgtt gcggcggtca gtgacttcgg cataccgatc
     4861 atcagagagg agtcattgac agaaagcaac ggagttacat gtttatcaac aatcgccatt
     4921 ttgatatgac gcgcttcgtc agtgatgatg cagaaacggg tcatttcaga ggccgtaccc
     4981 gccgtggtat tgatggcgat catcggcagc tgcggttttg cagagcggtc aacgccttcg
     5041 taatcgcgaa tatcgccgcc attggctgcc accagcgcaa taccttttgc gcagtcgtgc
     5101 ggagaaccac cgcctaagga gatcacgcta tcgcaattat tttctttaag taatttcaaa
     5161 cctgcggcga cgttttccgt ggtggggtta ggttgggtgc catcataaat aacgctaaaa
     5221 atattgcgtt cttccagtgc tttttgcaca tcacccgcca tacccaattt cgttaacata
     5281 ttgtcggtga caattaaggt acgggtaaat ccataatctg ccatcatatt cattgcatca
     5341 ttcaatgaat cagcaccaat aacattcacg gaaggaataa aaaaggttga agctgccata
     5401 acacactcct gaaagtgtaa aaaagggcgg gcagcttact gaggatttt
//
LOCUS       DADXDL010000166         5397 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.166, whole genome shotgun sequence.
ACCESSION   DADXDL010000166 DADXDL010000000
VERSION     DADXDL010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5397
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.166"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(88..300)
                     /locus_tag="IRB70_004636"
     CDS             complement(88..300)
                     /locus_tag="IRB70_004636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634454.1"
                     /translation="MNGFRNSSRNGQVWCWQRAGSRAVILEVSGRRMEAAEAWRRAAG
                     VAPRTDWQQFARKRAAHCHRRCRGRG"
     gene            complement(431..991)
                     /locus_tag="IRB70_004637"
     CDS             complement(431..991)
                     /locus_tag="IRB70_004637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fertility inhibition protein FinO"
                     /protein_id="HBC0634455.1"
                     /translation="MTEQKRPVLTLKRKTEGETPVRSRKTIINVTTPPKWKVKKQKLA
                     EKAAREAELAAKKAQARQALSIYLNLPTLDEAVNTLKTWWPGLFDGDTPRLLACGIRD
                     VLLEDVAQRNIPLSHKKLRRALKAITRSESYLCAMKAGACRYDTEGYVTEHISQEEEA
                     YAAARLDKIRRQNRIKAELQAVLDEK"
     gene            complement(1046..1792)
                     /gene="traX"
                     /locus_tag="IRB70_004638"
     CDS             complement(1046..1792)
                     /gene="traX"
                     /locus_tag="IRB70_004638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858383.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer pilus acetylase TraX"
                     /protein_id="HBC0634456.1"
                     /translation="MTTDNTNTTRNDSLAARTDTWLQSFLVWSPGQRDIIKTVALVLM
                     VLDHINLIFQLKQEWMFLAGRGAFPLFALVWGLNLSRHAHIRQPAINRLWGWGIIAQF
                     AYYLAGFPWYEGNILFAFAVAAQVLTWCETRSGWRTAAAILLMALWGPLSGTSYGIAG
                     LLMLAVSHRLYRAEDRAERLALVACLLAVIPALNLATSDAAAVAGLVMTVLTVGLVSC
                     AGKSLPRFWPGDFFPVFYACHLAVLGVLAL"
     gene            complement(1812..>5397)
                     /gene="traI"
                     /locus_tag="IRB70_004639"
     CDS             complement(1812..>5397)
                     /gene="traI"
                     /locus_tag="IRB70_004639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001463032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="conjugative transfer relaxase/helicase TraI"
                     /protein_id="HBC0634457.1"
                     /translation="GEQRPATIISEPDRNVRYARLAGDFAASVKAGEESVAQVSGVRE
                     QAILTEAIRSELKTQGVLGHPEVTMTALSPVWLDSRSRYLRDMYRPGMVMEQWNPETR
                     SHDRYVIDRVTAQSHSLTLRDAQGETQVVRISSLDSSWSLFRPEKMPVADGERLRVTG
                     KIPGLRVSGGDRLQVASVSEDAMTVVVPGRAEPATLPVADSPFTALKLENGWVETPGH
                     SVSDSATVFASVTQMAMDNATLNGLARSGRDVRLYSSLDEPRTAEKLARHPSFTVVSD
                     QIKARAGETLLETAISLQKAGLHTPAQQAIHLALPVLESKNLAFSMVDLLTEAKSFAA
                     EGTGFTELGGEINAQIKRGDLLYVDVAKGYGTGLLVSRASYEAEKSILRHILEGKEAV
                     TPLMERVPGELMETLTSGQRAATRMILETSDRFTVVQGYAGVGKTTQFRAVMSAVNML
                     PASERPRVVGLGPTHRAVGEMRSAGVDAQTLASFLHDTQLQQRSGETPDFSNTLFLLD
                     ESSMVGNTDMARAYALIAAGGGRAVASGDTDQLQAIAPGQPFRLQQTRSAADVVIMKE
                     IVRQTPELREAVYSLINRDVERALSGLESVKPSQVPRQEGAWAPEHSVTEFSHSQEAK
                     LAEAQQKAMLKGEAFPDIPMTLYEAIVRDYTGRTPEAREQTLIVTHLNEDRRVLNSMI
                     HDAREKAGELGKEQVMVPVLNTANIRDGELRRLSTWENNPDALALVDSVYHRIAGISK
                     DDGLITLEDAEGNTRLISPREAVAEGVTLYTPDKIRVGTGDRMRFTKSDRERGYVANS
                     VWTVTAVSGDSVTLSDGQQTRVIRPGQERAEQHIDLAYAITAHGAQGTSETFAIALEG
                     TEGNRKLMAGFESAYVALSRMKQHVQVYTDNRQGWTDAINNAVQKGTAHDVLEPKPDR
                     EVMNAQRLFSTARELRDVAAGRAVLRQAGLAGGDSPARFIAPGRKYPQPYVALPAFDR
                     NGKSAGIWLNPLTTDDGNGLRGFSGEGRVKGSGDAQFVALQGSRNGESLLADNMQDGV
                     RIARDNPDSGVVVRIAGEGRPWNPGAITGGRVWGDIPDSSVQPGAGNGEPVTAEVLAQ
                     RQAEEAIRRETERRADEIVRKMAENKPDLPDGKTEQAVREIAGQERDRADITEREAAL
                     PESVLRESQREQEAVREVARENLLQERLQQIERDMVRDLQKEKTLGGD"
BASE COUNT          997 a         1804 c         1378 g         1218 t
ORIGIN      
        1 acttcccgac cggatattaa aaaaagcaaa tctcataaac ttctttcagc cttctgactc
       61 ctggagtaat gaaggctgct tttttcgtta cccccttccc cggcaacgcc ggtggcagtg
      121 tgcagccctt tttcgggcaa actgctgcca gtctgtccgg ggcgcaacac cggcagcccg
      181 tcgccatgct tctgccgctt ccatcctgcg tccactgacc tccagaataa cggcccggct
      241 tccggcacgc tgccagcacc agacctgacc gttccgtgaa ctgtttctga atccattcat
      301 atttctgtcc ccctttagtt gtcagtatta ttgtgataaa tagctcagtg gaatggcttt
      361 ctttcgggta cggaagttat ttccttttaa gccttatttc cctgcctccc ctccctgagg
      421 gaggcttttt ttatttctca tcaagcacgg cctgaagttc tgcctttatc cggttctggc
      481 ggcggatttt atccagacgc gctgccgcat acgcttcctc ctcctgagaa atatgctccg
      541 tcacataccc ttccgtatca taccggcagg caccggcttt catggcacac agatagcttt
      601 ctgaacgggt gatggccttc agcgccctgc gcagtttttt atgcgagagc gggatattcc
      661 gctgcgccac gtcttccagt aacacgtccc ggataccgca ggccagaagc cggggcgtgt
      721 caccgtcaaa taatcccggc caccaggtct tcagggtgtt cacagcctca tccagtgtgg
      781 gcaggttcag ataaatggac agcgcctgtc tggcctgcgc tttttttgcc gccagctctg
      841 cttcccgggc tgctttctcg gccagcttct gctttttcac cttccacttt ggtggcgtgg
      901 tgacattgat gatggttttc cggctgcgga caggcgtctc cccttccgtt ttccgcttca
      961 gtgtcagtac cggtcgcttc tgctctgtca tgctgtgttc tgcctctgac gaatcatcct
     1021 cttgcggcca aagataccac acccgtcaca gcgccagaac gcccagcaca gccagatgac
     1081 aggcgtagaa taccgggaaa aaatccccgg gccagaaacg gggtaatgat tttcctgcac
     1141 acgacaccag accaacggtc agcaccgtca tcacaagacc ggccaccgcc gctgcatcac
     1201 tggtggcaag gttaagcgcc ggaataacag ccagcaggca ggcgaccagc gccagacgtt
     1261 ccgctctgtc ttccgcccgg tacagccggt ggctgactgc cagcatcagc agcccggcaa
     1321 tgccgtaact ggtgccggac aaaggccccc acagggccat cagaagaatg gccgctgctg
     1381 tacgccaccc actgcgcgtt tcacaccacg tcagcacctg tgccgccact gcaaaggcaa
     1441 acaggatatt cccctcatac cagggaaagc cggccagata atatgcgaac tgggcaataa
     1501 ttccccatcc ccacagccgg ttaatggccg gttgccggat atgcgcatga cgggacagat
     1561 tcagccccca caccagggca aacagcggaa aggctcctcg cccggccaga aacatccatt
     1621 cctgcttcag ctggaatatc agattgatgt ggtccagtac catcagcacc agcgccaccg
     1681 ttttgatgat atcccgctgt ccgggtgacc agaccagaaa cgactgcaac caggtatcgg
     1741 tccgtgcagc cagtgaatcg ttacgtgtcg tgttcgtgtt atccgttgtc atcagcgttt
     1801 atcttcctgt atcagtctcc gcccagggtt ttctctttct gcaggtcacg aaccatatcc
     1861 cgctctatct gctgcagacg ctcctgcagc agattttccc gggcaacctc ccggaccgct
     1921 tcctgctccc gttgtgattc acgcagcaca ctctccggca gcgcggcttc ccgttcagtt
     1981 atgtcagccc ggtcacgctc ctgcccggca atttccctga cagcctgctc tgttttgcca
     2041 tccggcaggt caggtttgtt ctctgccatt ttacggacaa tttcatctgc acggcgttcc
     2101 gtttcacggc ggatggcctc ttcagcctgc cgctgtgcca gcacctctgc cgtgaccggt
     2161 tcgccatttc cggctcccgg ctggacgctg ctgtccggga tatcccccca cacgcgacca
     2221 ccggtgatgg caccgggatt ccacggacga ccttcaccgg caattcttac caccacaccg
     2281 ctgtcaggat tatcacgggc aatccggaca ccatcctgca tattatcagc cagcaggctc
     2341 tctccgttac ggctaccctg cagggccacg aactgcgcat ccccgctgcc tttcacccgt
     2401 ccttcaccgc tgaatccccg cagcccgttt ccgtcatccg tggtcagtgg gttcagccag
     2461 ataccggcgg acttgccgtt acggtcaaac gccggcagtg ccacatacgg ctgcggatat
     2521 ttacgtcccg gtgcaataaa ccgtgcaggg ctgtctcccc cggccagccc tgcctgacgg
     2581 agaacggcac ggcctgccgc cacgtcccgc agttcccgtg ccgtactgaa cagccgctgc
     2641 gcattcatga cctcccggtc cggtttcggc tccagcacat cgtgggcagt tcctttctgt
     2701 acggcattgt taatggcatc cgtccagccc tgacggttat cggtgtacac ctgcacatgc
     2761 tgcttcatac gcgacagggc cacgtaggct gactcaaagc cggccatcag tttccggtta
     2821 ccttccgtgc cttcaagcgc gatggcaaag gtttcacttg tcccctgcgc accgtgggcg
     2881 gtgatggcat aggccaggtc aatatgttgc tctgcccgct cctgaccggg gcgaatcacc
     2941 cgggtctgct gtccgtccga cagcgtgaca ctgtcaccgg aaaccgctgt caccgtccag
     3001 acgctgttgg ccacataacc gcgctcccgg tcactcttcg tgaagcgcat ccggtcaccg
     3061 gttcccaccc ggattttgtc tggtgtgtac agtgtgacac cttcagccac cgcctcccgg
     3121 ggcgaaatca gccgcgtgtt accttccgca tcctccaggg ttatcagccc gtcatccttg
     3181 ctgataccgg caatccggtg atacacacta tccaccaggg caagggcatc cgggttattc
     3241 tcccaggtgg agagacgacg cagttctccg tcacgtatat tcgctgtgtt caggacaggc
     3301 accatgacct gctctttgcc cagctcaccg gccttttccc gtgcatcatg aatcatgctg
     3361 ttcagtacgc gccggtcctc attcaggtgc gtgacaatca gcgtctgctc ccgtgcttcc
     3421 ggtgtcctgc cggtatagtc gcggacaatg gcctcataca gtgtcatggg gatatccggg
     3481 aaagcctcgc ctttcagcat cgccttctgc tgcgcttctg ccagtttcgc ttcctggctg
     3541 tgactgaact ccgtcacgga gtgctccggt gcccatgcgc cctcctgacg gggaacctga
     3601 gacggtttca cactctcaag cccggacagt gccctttcca catcccggtt aatcaggctg
     3661 tataccgcct cccgcagttc cggcgtctga cgcacaatct ccttcatgat gaccacatcg
     3721 gcagcactgc gcgtctgctg cagacggaaa ggctgaccgg gcgcgatggc ctgcagctgg
     3781 tccgtgtcac cactggccac ggcacgaccg ccaccggccg caatcagggc gtatgcccgt
     3841 gccatatcgg tattgcccac cattgagctc tcatcgagca ggaacagcgt gttgctgaaa
     3901 tccggcgttt ctccgctgcg ctgctgcagc tgcgtgtcat gcagaaagga cgccagcgtc
     3961 tgtgcatcca cgccggcgct gcgcatctca ccgaccgcac ggtgcgtggg ccccagcccc
     4021 acaactcggg gacgctcact cgccggcagc atgttcacgg ctgacatcac cgcccggaac
     4081 tgtgtggtct tacccacacc ggcataaccc tgtaccaccg tgaaacggtc ggacgtttcc
     4141 agtatcatac gggtggcggc acgctgtccc gacgttaacg tctccatgag ttcgccgggt
     4201 actctctcca tcaacggcgt gaccgcctcc ttaccttcga gaatatggcg aagaatactt
     4261 ttttctgcct catacgacgc acgggaaacc agcagacctg tgccatagcc ttttgccaca
     4321 tccacataca gtaagtcacc gcgttttatc tgcgcattga tttcccctcc cagttcagta
     4381 aaaccggttc cttctgcagc aaacgacttc gcctctgtca gcaggtccac catgctgaag
     4441 gccaggtttt tactttccag cacaggaagg gccagatgaa tggcctgctg tgccggcgtg
     4501 tgaagcccgg ctttctgcag actgatagcg gtttccagca atgtctcacc ggcacgcgcc
     4561 tttatctgat cagaaaccac cgtaaaggag ggatggcggg caagtttttc cgcagtacgg
     4621 ggttcatcca gcgaggaata cagccggaca tcacgaccac tgcgggccag accgttcagg
     4681 gtcgcgttgt ccatcgccat ctgtgtgacg gaggcaaaaa ccgtcgcact gtcgctgacg
     4741 gaatgcccgg gcgtttccac ccagccgttc tccagcttca gtgccgtgaa tggtgaatca
     4801 gccacaggca gggtggccgg ttcagcccgc cccggcacaa caaccgtcat cgcatcttca
     4861 ctgacggatg ccacctgcag gcggtcaccg ccggagacgc ggagtccggg aattttccct
     4921 gtcaccctca gtcgctcgcc gtctgccacc ggcatttttt ccggccggaa cagcgaccag
     4981 ctgctgtcca gggaggaaat acgcaccacc tgcgtttcgc cctgcgcatc ccgcagggtc
     5041 aggctgtgac tctgcgctgt cacccggtct atcacatagc ggtcatgact gcgtgtctcc
     5101 gggttccact gctccatcac catccccggt cggtacatat cccgcagata acggctccgg
     5161 ctgtccagcc agaccggtga cagtgcagtc atggtcacct cagggtgtcc gagcacgccc
     5221 tgcgttttca gctcactgcg aatggcctct gtcagtatgg cctgttcccg taccccgctg
     5281 acctgtgcca cgctctcttc tccggctttc acgctggccg caaaatctcc ggccagccgg
     5341 gcatagcgga cattacggtc cggttcactg atgatggtgg ccggtcgctg ttctccc
//
LOCUS       DADXDL010000167         5388 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.167, whole genome shotgun sequence.
ACCESSION   DADXDL010000167 DADXDL010000000
VERSION     DADXDL010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5388)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5388)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5388
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.167"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(126..1148)
                     /locus_tag="IRB70_004640"
     CDS             complement(126..1148)
                     /locus_tag="IRB70_004640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrD"
                     /protein_id="HBC0634458.1"
                     /translation="MDKRVIFAVAGSGKTTLLIRRLREDRRTLILTFTVNNEAHLRAQ
                     IIRRFGYIPYGIRVMTWFEFLHGFCFRPFLQEQLSSRGLSFNQPPSRIPRTNIRHYQD
                     PAGRLYHRRLAHLLTARGLLPDIRTRLARYYDELFVDEVQDFAGHDFNFLLELCRAEI
                     SVLCCGDFYQHTFDTSRDGNVNATLHEDITRYEARFRAAGIMVDCETLSRTWRCSATV
                     CEFITGQLNIRISAHGTHTTQIEIVTDEARSAALHADNTMIKLFYREHHRYGCHSMNW
                     GGSKGLDHFQDVCIVMGANHWMRLIQQKLAALPPSSRNRLYVACSRARGNIYFIPESH
                     LRRFRN"
     gene            complement(1133..2698)
                     /locus_tag="IRB70_004641"
     CDS             complement(1133..2698)
                     /locus_tag="IRB70_004641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBC0634459.1"
                     /translation="MPLITRLMLQNFKKFPELDLRFSNDRNILVGDNESGKSTILLAL
                     DLVLSDSRHRVEALGVESLLSQSAVRHFQEGERRADQLPVLTADVFLSNGGEPDLNGR
                     QNLAGIDADGLRMRIAPMMEEYGQDIHHVLQQDPDNFPYEYYSVQFSTFSGGHFAGFR
                     RYLRHLFLDSARIDNEHAAQEYTRTVYSVNVPVADRYRLENSYRQQKMHFCARHLSAI
                     NDTLKTYQFGVRSGAKSGLEANLDITEDGISIRHRGKGRQCFIKTEFALQRHQQQGGE
                     IHALLLEEPENHLSHVSMKRLVNQLATERQTQVFIATHSSHISSRLDLRKAILLGATR
                     PVLMNELSAETAAFFMKAPDNNVLEFALARRVLLVEGDAEFILIEAFYHRLYGRAPED
                     DGVHIIAIGGTSFRRYLELARLLENRVAALRDNDGNYQQNCDERYADVLCSRSRVFAD
                     HDNSRSTFEICLYQDNADLCDALFRGTRRTLTVQDYMLANKAEAAFQLLQLHAEKLTV
                     PDYIQEALAWIRE"
     gene            complement(2773..3189)
                     /locus_tag="IRB70_004642"
     CDS             complement(2773..3189)
                     /locus_tag="IRB70_004642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system VapC family
                     toxin"
                     /protein_id="HBC0634460.1"
                     /translation="MNKIYMLDTNICSFIMREQPEALLKHLEQSVLRGHRIVVSAITY
                     SEMRFGATGPKASPRHVQLVDAFCERLDAVLPWDRAAVDATTEIKVALRLAGTPIGPN
                     DTAIAGHAIAACAILVTNNVREFERVPGLVLEDWVR"
     gene            complement(3186..3416)
                     /locus_tag="IRB70_004643"
     CDS             complement(3186..3416)
                     /locus_tag="IRB70_004643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005229629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB/MazE/SpoVT family DNA-binding
                     domain-containing protein"
                     /protein_id="HBC0634461.1"
                     /translation="MRTVSIFKNGNNRAIRLPRDLDFEGVSELEIVREGDSIILRPVR
                     PTWGSFLELEKADPDFMTEREDVVSDEGRVNL"
     gene            3797..>5388
                     /locus_tag="IRB70_004644"
     CDS             3797..>5388
                     /locus_tag="IRB70_004644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001505097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pcar"
                     /protein_id="HBC0634462.1"
                     /translation="MPVLSANKAQEEQINTSYEPLTPSVITDEKAQSYIEALNFACSR
                     PDIRNIAVTGPYGAGKSSVLLTWERAEDNDFRVMTVSLADFEMQRAYPGDSLSVEGKP
                     DYDDNEKKAGKAEEKTIEYSILQQLLYKEKKSVLPYSRLERISDVSACQIAMMTASLL
                     FILASTATGLLFLFPDYIREKLSLSPELSQFLLELPVLARFGSAGIFLFTALFFALKK
                     LHRTGVFDRRVSIDKVDILKGAITTRPAAPSLLNVYIDEIVYFFEQTQYNVVIFEDLD
                     RHNDGAIFIKLREINQLINNCLPTDNPVRFIYAVRDNLFITPESRTKFFDFVIPVIPV
                     MDSENASEHFLSKFTLDELRQEGFKDCLARLALFIPDMRVMHNIANEFRLYRNIVNNG
                     GDLKRLISLITYKNLYAEDYHRIDQKKGMLYSIVSEYTSGKLREDYCNNLKNKIETCL
                     TELSKLHNEEVVTEHELRSEILRPYISEKTAPRLHIMTGTGGQYDFDDVIQNENTFLS
                     LLSNQIISIKPSGYNITITTID"
BASE COUNT         1358 a         1347 c         1330 g         1353 t
ORIGIN      
        1 tatcatctgc gggtttccct ccacgcaggt ccggtttccg gcgaaaccgg agcctcattt
       61 ttcggcctga agttttgtcg ttgactactt tttaccggct tgtgcccagt tgagaagccg
      121 ctgacttagt ttctgaatct ccgaagatgg ctttccggaa taaaatagat gttgccccgt
      181 gcccgtgagc aggccacgta tagcctgtta cgggatgatg gtggaagtgc tgccagcttc
      241 tgttggatga ggcgcatcca gtggttggcc cccatcacga tgcagacgtc ctgaaagtgg
      301 tcgagtcctt tactgccccc ccagttcatt gagtggcatc cgtaacggtg atgttcgcga
      361 tagaagagct tgatcatcgt gttgtccgcg tgcagggccg ctgaacgcgc ttcatccgtg
      421 acgatttcaa tctgggtggt atgtgttcca tgagccgaaa tgcgaatgtt cagttgtccg
      481 gtaatgaact cacacactgt agctgaacag cgccatgtcc ggctgagcgt ctcacaatcc
      541 accatgatac ccgcagccct gaagcgagcc tcgtatcggg ttatgtcttc atgcagcgta
      601 gcattgacgt taccgtcgcg gcttgtgtca aaggtatgct gataaaaatc cccgcagcac
      661 agcactgaga tttccgcgcg gcatagctcc agcagaaaat taaagtcatg gccggcaaag
      721 tcctggactt catcaacgaa caactcatcg tagtaacggg caagtcgggt acggatatct
      781 ggcagcaacc cccgggctgt cagcaggtgt gcgagccgcc ggtgatacag ccgtccggcg
      841 ggatcctgat aatgccggat attcgtgcgc ggtattctgg aagggggctg gttgaagctc
      901 agaccacgcg atgacagttg ctcctgcagg aaagggcgaa aacagaaacc gtgcagaaac
      961 tcaaaccagg tcatcacacg gatcccgtac ggtatgtagc caaagcgtct gataatctgc
     1021 gcccgcagat gtgcttcatt atttacggtg aaggtcagga tcagcgtccg ccggtcctct
     1081 cttaaccgac gtatcagcag cgtggtttta cccgagccgg caaccgcaaa tatcactctc
     1141 ttatccatgc cagtgcctcc tggatataat caggaacggt cagcttttcg gcgtgcaact
     1201 gtaacagctg gaatgctgct tctgccttat tggccagcat gtaatcctga accgtgagtg
     1261 tccggcgggt tccgcggaaa agcgcatcac acaggtcggc attatcctga tacaggcaga
     1321 tttcaaatgt ggagcggctg ttgtcgtggt cagcaaatac ccgggagcgg gaacaaagca
     1381 cgtcagcata gcgttcatcg caattttgct gatagttgcc gtcattgtcg cgaagggccg
     1441 cgacacgatt ttccagaaga cgggccagtt caagataacg acggaaactc gttccgccga
     1501 tagcgatgat gtgaaccccg tcatcctccg gtgccctgcc atacaggcgg tgataaaagg
     1561 cctcgatcag aataaactca gcatccccct ccacgagcag cacgcgtctg gccagcgcaa
     1621 attccagcac gttattatcc ggtgctttca tgaagaaggc ggcagtctca gcggaaagtt
     1681 cattcatcag taccggccgg gtagctccga ggagaatagc cttacgtagg tcgaggcggg
     1741 aggagatatg gctactgtgt gtggcaataa acacctgcgt ctgccgttcc gtggcaagct
     1801 gattaaccag cctcttcata ctgacatggc tgagatgatt ctccggctcc tcaagcaaca
     1861 gcgcgtggat ctctcccccc tgctgctgat gccgctgcag cgcaaactcc gttttgatga
     1921 aacactgtct tccttttccg cggtgacgaa tggaaatacc gtcctcagta atgtccaggt
     1981 tcgcctcaag acctgattta gcgccggaac gcacgccaaa ctgatacgtt ttcagcgtgt
     2041 cgtttatggc ggacagatgc cgggcgcaga agtgcatttt ctgttgccgg taactgtttt
     2101 caagccggta ccgatcggcc accggcacat tgacgctgta aactgtgcgc gtatactcct
     2161 gtgcggcatg ctcgttatca atgcgtgcac tgtctaagaa cagatggcgc agatagcgtc
     2221 tgaagcctgc gaaatgacca ccggagaatg tgctgaactg cacggaatag tattcatagg
     2281 gaaaattatc aggatcctgc tgcaaaacat ggtgtatatc ctgaccgtat tcctccatca
     2341 tgggagcaat gcgcattctg agaccatccg catcgatacc cgccagattt tgcctgccgt
     2401 tcaggtcagg ctctccccca ttactcagga aaacgtcagc ggtcagcacg ggtaactgat
     2461 cggcacggcg ctcaccttcc tgaaaatgcc tgactgctga ctgtgacagg agcgattcca
     2521 cccccagcgc ctcaacccga tgcctgctgt cactcagcac aaggtcaaga gccagcagaa
     2581 tagtgctttt cccggactca ttgtccccaa ccagaatgtt acgatcgttg ctgaagcgca
     2641 ggtccagttc cggaaacttt ttgaagtttt gcagcataag ccgcgtgatc agtggcattt
     2701 ttttattcct ttatataccg ctgcctgaaa gagcggccgg ccgcgcctga ccgcctgttt
     2761 tgttttacag cgttatctta cccagtcttc cagcacaaga cccggtaccc gctcaaactc
     2821 tctcacatta ttcgtcacca gaatggcaca ggcagcgatg gcgtgtccgg ctatcgccgt
     2881 gtcgttcgga ccgatcggcg tgccggcgag acgcagtgcc accttaatct ccgtggtcgc
     2941 atccaccgcg gcgcggtccc acggcaggac ggcatcgagc ctctcacaga acgcgtcaac
     3001 cagttgcacg tggcgtggcg aggccttcgg accggtggca ccgaagcgca tctcggagta
     3061 ggtgatggcc gagaccacga tacggtgacc gcgcagcacc gactgctcca ggtgcttaag
     3121 caatgcttca ggttgctcgc gcatgatgaa cgagcagatg ttcgtgtcga gcatatagat
     3181 cttgttcaca ggttaactcg tccttcgtcg ctgacaacgt cctcgcgctc cgtcataaag
     3241 tccggatcgg ccttttctag ctccaggaat gagccccagg tcggccggac ggggcgcaga
     3301 atgatgctgt ccccttcccg gacgatctcc agctcgctca ccccctcaaa atccagatcg
     3361 cgtggaaggc ggatagcacg gttgttgcca tttttaaaaa tggatacggt tctcatgatt
     3421 ctctcccggg taagtgtgga tatgtgatgc atatccggaa tgatgttcat tgcaccgggt
     3481 gtgtgcatat gtttagtata ggcagatgtt aggcatatgt atagattcag catatgcaga
     3541 tggtgaggat atgcgtatac catgaatatg cagatgtcag gcatatggat atgttcagcc
     3601 tatgttattt tctctctttc cccgtgcaga tccggtttct ggtgaagtcg gagtccacca
     3661 tctccgagta tttgataagc caattcttgt atccctttgc ctttattatc tttttggttt
     3721 tcagaagtta taatgcctgt taaatcaaca atgttggaag atcaacatga gaagaccatc
     3781 ccgaactgaa gcactgatgc cagtactgag tgctaacaaa gctcaggaag aacagattaa
     3841 cacctcctat gaaccactga ctccctcagt cattacagat gaaaaagcac aaagctatat
     3901 cgaagctttg aattttgcct gttctcgccc ggatatcaga aatattgcag taacagggcc
     3961 gtacggggcc ggtaaaagtt cggtattact gacatgggaa agggcggagg ataatgactt
     4021 tcgggtgatg accgtatcac tggctgactt tgaaatgcag cgggcatacc ccggagattc
     4081 gctgtcagtt gagggtaagc ccgactatga tgataacgaa aaaaaagcgg gaaaagccga
     4141 agagaaaaca atcgagtaca gcatcctgca acaactgctc tataaagaga aaaaaagtgt
     4201 gttaccctat tcccgtctgg agcgcatttc tgacgtaagt gcgtgtcaga tagccatgat
     4261 gacggccagt ctgttattca tactggcttc gacggcaact ggtctgcttt ttcttttccc
     4321 ggattacatc cgggaaaagc tctccctgtc gccagaactg agtcagtttc tgctggagtt
     4381 gcctgtactc gctaggtttg gtagcgccgg gatatttctt tttactgctt tattctttgc
     4441 actgaagaaa ttgcaccgta caggggtatt tgatcggcgt gtaagtattg ataaagttga
     4501 catactgaaa ggtgccatta caacacgccc tgcggcccct tctcttctca atgtgtacat
     4561 tgatgaaatc gtctactttt tcgaacagac acaatacaat gtagtcatat ttgaggatct
     4621 tgaccgtcat aatgacggag ccatttttat caaactccgg gaaataaatc agcttatcaa
     4681 taactgcctc cccacagaca atcctgtccg atttatctac gctgtcaggg ataatctttt
     4741 cataacacca gaatcacgga caaaattttt cgatttcgtc ataccagtaa tcccagtaat
     4801 ggacagtgag aatgcttctg agcattttct aagtaaattt acacttgatg aactcaggca
     4861 ggaaggattc aaagactgcc ttgccagact ggctcttttt attcctgata tgcgggttat
     4921 gcataacatt gcgaatgaat ttcgtcttta ccggaatatt gtgaataatg gaggagattt
     4981 aaagcgtctt atttcactga tcacctataa aaacctttat gctgaagact atcacaggat
     5041 agatcagaaa aaaggaatgc tttatagcat tgtatctgaa tatacatcag gtaaattaag
     5101 agaggattat tgcaataatc taaaaaacaa aattgaaacg tgtctaactg aactatctaa
     5161 actacataat gaagaagtgg tcactgaaca tgagttaaga agtgaaattt tgcggccata
     5221 tatcagtgaa aaaacagcac cccgattaca tattatgaca ggtacaggag ggcaatatga
     5281 ttttgatgat gtaatccaaa atgaaaatac atttctttct ttgctgagca accaaataat
     5341 cagcattaaa cctagtggat ataacattac tataacaaca atcgataa
//
LOCUS       DADXDL010000168         5281 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.168, whole genome shotgun sequence.
ACCESSION   DADXDL010000168 DADXDL010000000
VERSION     DADXDL010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5281
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.168"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            391..519
                     /locus_tag="IRB70_004645"
                     /pseudo
     CDS             391..519
                     /locus_tag="IRB70_004645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014543172.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS481 family transposase"
     gene            complement(554..847)
                     /locus_tag="IRB70_004646"
     CDS             complement(554..847)
                     /locus_tag="IRB70_004646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001105065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634463.1"
                     /translation="MNYDEITKITAERISDYMTEAVNTDSIAVAEMFHNAAWGARTLW
                     FELVTKIDIDIHKKNRYASYDLRRKIEMQHEEFQKMTEREQVPLLKCISSDLI"
     gene            complement(953..1228)
                     /locus_tag="IRB70_004647"
     CDS             complement(953..1228)
                     /locus_tag="IRB70_004647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBC0634464.1"
                     /translation="MELKWTSKALSDLSRLFDFLVLASKPAAARTVQSLTQAPVILLT
                     HPRMGEQLFQFEPREVRRIFAGEYEIRYEINGQTIYVLRLWHTRENR"
     gene            complement(1228..1512)
                     /locus_tag="IRB70_004648"
     CDS             complement(1228..1512)
                     /locus_tag="IRB70_004648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribbon-helix-helix protein, CopG family"
                     /protein_id="HBC0634465.1"
                     /translation="MQMKNNAAQATKVITAHVPLPMADKVDQMAARLERSRGWVIKQA
                     LSAWLAQEEERNRLTLEALDDVTSGQVIDHQAVQAWSDSLSTDNPLPVPR"
     gene            2117..2869
                     /locus_tag="IRB70_004649"
     CDS             2117..2869
                     /locus_tag="IRB70_004649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000562172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBC0634466.1"
                     /translation="MIATKTPAIDKAARIFHFIAGKGSATYSEIHQNVGLPQSTTSAL
                     LASLTTHAFLRQKNGRYYLGLIFYELGNKAIQDFDFRELAEESLVFLRDQTRLACHLG
                     VLDGSTGIYLAKKESQNAIIVRSWTGKRLSLHSSSLGKVLLAWLPEDHIDALLPTEHL
                     PAFTARTITTRKALKAELEVVRLQGWAFDNQEDVDDVTCIAAPVFNSDQAVVAAISIS
                     GVRFQMPEEKIPEYANAVMKAAGMMSEKLCGI"
     gene            complement(2915..3880)
                     /gene="kdgT"
                     /locus_tag="IRB70_004650"
     CDS             complement(2915..3880)
                     /gene="kdgT"
                     /locus_tag="IRB70_004650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001022265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-keto-3-deoxygluconate transporter"
                     /protein_id="HBC0634467.1"
                     /translation="MNIKKTVEKIPGGMMLAPLFLGAVLHTFWPGTGKYFGSFTNGMI
                     TGVVPILAVWLFCMGASIKISATGTVLKKSGTLVATKIATAWVCAFVFAQLLPEGGMV
                     KTGFFAGLSVLAIVAAMDMTNAGLYASLMQEYGTKEEAGASVLISLESGPLMTMIILG
                     SAGQATFEPEHLAGVLIPFLVGFLLGNLDPELRELFSRATKSLIPFFAFALGNTINLG
                     VIIDTGLLGILMALAVIVITGVPLIIMDIMLGKGRGTAGIAASSTAGAAVATPLLVAE
                     IAPDFAEAAPAATTLVASCVVITAIVVPVITALWAKHGASRVRAT"
     gene            complement(3913..4293)
                     /locus_tag="IRB70_004651"
     CDS             complement(3913..4293)
                     /locus_tag="IRB70_004651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003754044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RidA family protein"
                     /protein_id="HBC0634468.1"
                     /translation="MKKDIIYTTGAPVPGGALSQAVKAGETIYLAGQVGFDPHTMQVV
                     STDFDEQARQAFKNLLSVAEAAGGSDRDIVKLNAYLTDVNMFPRFNAIMSEYFSPPYP
                     ARATLGIAALPQGAVIEIEAIMVL"
     gene            complement(4318..5208)
                     /locus_tag="IRB70_004652"
     CDS             complement(4318..5208)
                     /locus_tag="IRB70_004652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001077068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrodipicolinate synthase family protein"
                     /protein_id="HBC0634469.1"
                     /translation="MNQTMKFSGAVCPSVIPLDDSGQIDLTGLEKHMARLSDSGINGI
                     LLSGTIGEFATMSVRERAMLILEARKMSDLPLIAHISSTVEEDMLYLADAAYDSGYDA
                     VMVLPQYYYAQTSRQLLSYFRSLDRKLAGDWFIYNFPARTGCDVDAHLVRMLAESCPR
                     FIGIKDTVDCASHTRAIVNAVTPLRKDFAVFAGFDEYFVPNLMNGGAGVLSGLNNVVP
                     ELFAQIMRAYRAGDLNEVAGLHKEIGRLSGIYAIGDDFVSTIKTAISRKYGYMTPVSR
                     NHNGQLTADQADCLDKLFGL"
BASE COUNT         1348 a         1301 c         1291 g         1341 t
ORIGIN      
        1 cgttattaag ctatcaggta taagtgactt caaaatacat agctacatta ttaaaacaag
       61 tgaatatcct gaagagtttt tttccaatgc agcatgggat aaaaaaaata taaaaccggg
      121 ggattattac tctgtgcagg ctgtttctat gtttacgaca aaccagttta ttctcctttg
      181 tcctaaggat attataaagt tttatcggga aagctggaag ttcgagttgc ttaatgtaga
      241 cttcgatata aataccagga agaaactcca ggaagaagct gcatattgcg taccaatttc
      301 tgcaatatct gtaaaacgat gggatatgcc tcttcagggc tcgaaaccct caagttagaa
      361 ggcaactagg gcgactgtat tctgtgacga aatgaatggc tggctcacta taataatgag
      421 cgaacccatc agggaaaaat gtgcaatggg cggacgccaa tggaaacgtt actcgatgga
      481 aaacgcatct gggccgagaa aaatttaagc cagatgtaat ctgacagata cctgtataaa
      541 taaccgataa ctgtcagatc aggtctgagc taatacattt caataaaggt acttgctcgc
      601 gctctgtcat tttctgaaac tcttcatgct gcatttcgat tttccttcta agatcataac
      661 tcgcatacct gttcttttta tgtatatcta tatctatttt tgtgacgagt tcaaaccaca
      721 atgttcgcgc tccccatgca gcgttatgaa acatttccgc aacggctata gagtctgtat
      781 taactgcttc agtcatgtag tcgctaatac gttcagcggt aattttcgtt atttcatcgt
      841 aattcatttt atctcctaca agattattta atggaatgca aaatatctgg tctgataata
      901 atgttccaga attaatatct gcaggctatg ttaagttgtc cccacacaca atctacctgt
      961 tttctcgtgt gtgccacaga cgcaatacat aaatagtctg gccattaatt tcgtaacgga
     1021 tttcgtactc gccagcaaaa atccgtctga cctccctggg ttcaaactga aacaactgtt
     1081 ctcccatacg tggatgagtt aacagaatga ccggtgcctg tgtcagggac tgtaccgttc
     1141 tggcggcagc aggtttactg gccagcacca gaaaatcaaa taaccgcgac aaatcagaaa
     1201 gcgccttact ggtccacttc agttccatca gcgtggcacc ggtaacggat tgtcagtact
     1261 gaggctgtcc gaccaggcct gtacagcctg atggtcgata acctgtccgg atgtcacatc
     1321 gtccagggct tccagcgtca ggcgattacg ctcctcctcc tgggcaagcc atgcagaaag
     1381 cgcctgtttg ataacccagc cccgggaacg ttccagtctg gcggccatct ggtcgacttt
     1441 atcagccata ggtaatggca catgcgcggt aattactttt gttgcttgtg cggcattgtt
     1501 tttcatttgc atatccgatt agttgttaat catatttaat catagtgatt actttcagac
     1561 ggaacaaggc aaataatgcg cgtcagcgca tgtaaggcgg catacggagg ttacatgtag
     1621 cacaggtgta aaaccgccga agcccggcgt aagccggtac tgattgatag atttcacctt
     1681 acccttttcc atcctgctaa gccacacccg ctttcagcta tgagagagcc tttgtgcgca
     1741 gtcggggcgt atctccgcgt tagcgggccg tgagggacgc ttacgagcgt ggatgagaga
     1801 cgtacagtgg tttcttctag cttttatttc ctctcaggtc ccgaattgtc aacttctgaa
     1861 tcgtgggggc ccctttgggg tgacgattca gtggttgaca actgcacata aaacaccctg
     1921 tgtgtggggt gatggttcac gtagtggtcc atcgccctgc caggggtcag tcgccactac
     1981 accatcactt gagaaagaga agggacttgc tgttatgtca gtgaaacttt ggtaaattat
     2041 cgtatcctgt ggcaggatga tggtttgtta cagcattgca attcattaaa aagggggctt
     2101 acgaagaaca gtggatatga tcgcaactaa aacgcctgcc attgataaag ctgcccgaat
     2161 atttcatttt attgccggga aaggctctgc cacctacagt gaaattcacc agaatgtcgg
     2221 attgcctcaa agcaccacct cggccctgct tgccagcctg accacgcatg cctttctgag
     2281 acaaaaaaat ggccggtatt atctggggct aatcttttac gagcttggta ataaagccat
     2341 tcaggatttt gattttcgtg aactggctga agagtcactc gtttttctcc gtgaccagac
     2401 ccgtcttgcc tgccatctgg gcgttctgga tggttccacc ggcatctatc tggcgaaaaa
     2461 agaaagccag aatgcgatta tcgttcgcag ctggacggga aaacgacttt ccctgcacag
     2521 ttcctccctt gggaaagtgt tgttggcctg gcttccggaa gaccacattg atgctctttt
     2581 acccacagaa caccttcctg cgtttactgc ccggacaatt acaacacgta aagcgttgaa
     2641 agctgagctg gaggtggtcc gcctgcaggg atgggcgttt gataatcagg aagatgtcga
     2701 cgatgtcacc tgtattgccg cgccggtatt taacagtgat caggccgttg ttgccgcaat
     2761 aagtatttcc ggggttcgtt ttcagatgcc tgaggaaaaa atacctgagt atgcgaacgc
     2821 ggtgatgaaa gccgctggca tgatgtctga aaagttatgc ggtatatgac tggtccgctc
     2881 acaggtcatg ataacccgtg agcggcgttc ggccttacgt tgctctgacg cgggaggctc
     2941 cgtgttttgc ccacaacgca gtgatcaccg gcacgacaat ggcggtgatc accacacagg
     3001 atgccaccag agtagtggct gccggtgcgg cctcagcgaa gtccggcgcg atctcggcta
     3061 ccagcaacgg agtggccacg gcagcgccag cagtactcga tgcggcaatt ccagccgtgc
     3121 cacggccctt acccagcatg atatccatga ttatcagtgg tacgcctgtg ataacaatga
     3181 ctgccagagc cataagaata cccagcagtc cggtgtcgat gatgacgcca agattaatgg
     3241 tattccccaa cgcaaatgca aagaatggga tcagactttt ggtggccctg gaaaacaatt
     3301 cccgaagttc gggatcaaga ttacccagca aaaaccccac cagaaagggg atcaggacgc
     3361 cggcgaggtg ttcaggttcg aacgttgcct gcccggcgga ccccagaata atcatcgtca
     3421 tcagggggcc ggactcaagc gagataagta cagaagcacc ggcttcttct tttgtgccgt
     3481 actcctgcat cagggaagca taaagcccgg cattggtcat atccatcgcc gcaacaatcg
     3541 ccagaacaga taaaccggca aagaaacctg tttttaccat tcccccttcc ggtaggagct
     3601 gggcaaaaac aaaggcacag acccaggcag tggcgatttt tgtggctacc agtgtgccag
     3661 actttttgag aacggtcccg gttgcactga ttttaatgga ggcgcccata cagaacagcc
     3721 agacagcgag gatggggacc acgccggtga tcatgccatt agtaaatgaa ccaaagtatt
     3781 tgccggtacc tggccagaag gtatgcagta ccgcccccag aaacaggggg gccagcatca
     3841 ttcctcccgg aattttttca actgtttttt tgatattcat tatcgtccct ttttaatgtc
     3901 agatacggcc agtcagagca ccatgatggc ttcaatttca ataacagccc cctgcggcag
     3961 ggcggcgata cccaacgtag ccctggcggg gtacggtggc gaaaagtatt ccgacataat
     4021 ggcgttaaat cgcgggaaca tgttcacgtc ggtcagatag gcattcagct tcacaatatc
     4081 cctatcactc cctcctgcgg cctctgccac cgacagcaaa tttttaaacg cctgacgggc
     4141 ctgttcatcg aaatctgttg agaccacttg catggtatgc gggtcaaaac cgacctgacc
     4201 ggcgagataa atggtttccc cggctttcac cgcctgagat aatgccccac cggggacagg
     4261 agccccggtg gtataaatga tgtctttttt catgatgtgc ctcctgtcct tttgcggtta
     4321 cagaccgaac aatttgtcta ggcagtctgc ctggtcggct gttaactggc cgttatgatt
     4381 ccgtgagacc ggcgtcatgt agccatactt tctggaaatg gcggttttga tcgtactgac
     4441 aaaatcatca ccaatggcat atatcccgga aagtcgccca atttctttgt gtaatccggc
     4501 gacttcattg aggtcgccgg cccgataggc ccgcataatt tgggcaaaaa gctccggcac
     4561 cacattattc agtccggaaa gaactccggc gcctccgttc atcagattgg gtacaaagta
     4621 ctcatcaaaa ccggcgaata cggcaaaatc ttttctcagc ggtgtgaccg cgttgacgat
     4681 ggcccgggtg tgagacgcac agtccacagt atctttgatg ccaataaacc gcgggcagct
     4741 ttccgccagc attctgacaa ggtgagcatc cacatcacat ccggttctgg ccgggaagtt
     4801 atagataaac cagtcaccgg caagtttacg gtcaagactg cggaaatagc taagtaactg
     4861 acgggatgtc tgggcgtagt aatactgtgg cagtaccatt actgcgtcat agccactgtc
     4921 ataggcggca tcagccagat aaagcatgtc ctcttcaacg gtagatgaaa tatgggcaat
     4981 caaagggagg tcactcattt tccgggcttc caggatgagc attgcccgtt cgcggacgct
     5041 cattgtggca aattccccga tggtacctga tagcagaatg ccgttgatgc cggaatcaga
     5101 aaggcgtgcc atatgttttt ccagccccgt gaggtctatc tgaccgctgt catccagagg
     5161 aatgacggaa gggcagactg cccctgaaaa cttcattgtc tgattcatat tatttgttcc
     5221 ttttgcgtgg tatcagcgtc atgcctgctg atacccgccc cggcctttac ggaagaagga
     5281 t
//
LOCUS       DADXDL010000169         5144 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.169, whole genome shotgun sequence.
ACCESSION   DADXDL010000169 DADXDL010000000
VERSION     DADXDL010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5144)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5144)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5144
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.169"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(339..578)
                     /locus_tag="IRB70_004653"
     CDS             complement(339..578)
                     /locus_tag="IRB70_004653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase V"
                     /protein_id="HBC0634470.1"
                     /translation="MPRHYEIDSAWRASIKREPNGRQTVTTEAFVSQLALINFHWSCR
                     QANQWIETYVTVFKDISTQEGENRTFMLFNPNGGR"
     gene            680..1900
                     /locus_tag="IRB70_004654"
     CDS             680..1900
                     /locus_tag="IRB70_004654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000343760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISKox3 family transposase"
                     /protein_id="HBC0634471.1"
                     /translation="MDEKSLYAHILNLSDPWQVKSLSLDENAGSVTVTIEIAENTRLA
                     CPTCGKSCSVHDHRHRKWRHLDTCQFTTIVEADVPRIMCPEHGCLTLPVPWAGPGSRY
                     TLLFESFVLSWLKISTVDAVRKQLKLSWNAVDGIMTRAVKRGLARIKKPLSARHMNVD
                     EVAFKKGHRYITVISDRDGRALALTDDRGTESLAGYLRTLTDGQLLAIKTLSMDMNAG
                     YIRAARIHLPSAVEKIAFDRFHVAKQLGEVVDKTRQNEHPHLPVESRHQAKGTRFLWQ
                     YSDKWMTESRQEKLMWLRAQMKLTSQCWALKELAKDIWNRPWSEERRSDWQRWLALAA
                     NSDVPMMKNAAKTIGKRLYGILNAMRHSVSNGNAEALNSKIRLLRIKARGYRNRERFK
                     LGVMFHYGKLNMAF"
     gene            complement(1989..2651)
                     /locus_tag="IRB70_004655"
     CDS             complement(1989..2651)
                     /locus_tag="IRB70_004655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBC0634472.1"
                     /translation="MTQTVPKGFVRAYLRASTTEQDATRALDTINTFAIERGLSICNY
                     YIENESGSKLERPELFRLLKDCQQNDILLVEDVDRLSRLVGEDWNTLKKMIRQKDIRV
                     VAVNVPTTWLASGHNDFDSRMFSAINDMLLDMLAAVARRDYEQRRERQQQGIARAKRE
                     GKYKGRQVNQSRYDAINRLIASGSSWSQIQKVLGCSRATISKAVKQQTVNKMNHEPEG
                     RE"
     gene            3032..3694
                     /locus_tag="IRB70_004656"
     CDS             3032..3694
                     /locus_tag="IRB70_004656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000516401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-arginine deiminase"
                     /protein_id="HBC0634473.1"
                     /translation="MGKILLVVSDKGGVGKSTYVANTGSMLVNKGKSVIILKTDKNHD
                     LLSWNEKRTDNGLLTIPVHAAYGNVSNEIKRLSKLCEVLIVDCPGHDSQEFRSALTVS
                     DIVVTLVKPSSDFESETLTSVTEKIRTAQKANAALEPWVLFTRINSAKPRHRKAAIDL
                     DKLLRSDNIWIQPLKTRISELDVYESACNEGAGVHDVSRASSLSTAKAQIELVAQEIG
                     IL"
     gene            3794..4078
                     /locus_tag="IRB70_004657"
     CDS             3794..4078
                     /locus_tag="IRB70_004657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001371664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopG family transcriptional regulator"
                     /protein_id="HBC0634474.1"
                     /translation="MALKLNRPNIDESQQPATNAETARFISGATRAPVAGKPKLMNFR
                     LPAYFEEILEAEAQRTGQSKTTVLKAALAAFDNLDENLKNHWLLESAKLG"
     gene            4284..4595
                     /locus_tag="IRB70_004658"
     CDS             4284..4595
                     /locus_tag="IRB70_004658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000469598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634475.1"
                     /translation="MFIFRYIKTLINIYLLYIQPILGMFLIGIGLWGFYAPDEGTCTN
                     LNIELCAVSAIDVLKPAIFVFLGIITVAGWYFTELQPKLRGEGKYMKVKTGVKPEDFV
                     K"
     gene            4631..4915
                     /locus_tag="IRB70_004659"
     CDS             4631..4915
                     /locus_tag="IRB70_004659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001043731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634476.1"
                     /translation="MNKSWLEQQVQNEKLKKVQEEKKDGTIQKGLYRVRIKDKYRWDL
                     WENDFRVVIAYSKDDAELKFTEMTGFNEHYYIESIEKIVLSDIEKILLEN"
     gene            complement(4936..>5144)
                     /locus_tag="IRB70_004660"
     CDS             complement(4936..>5144)
                     /locus_tag="IRB70_004660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DNA distortion polypeptide 3"
                     /protein_id="HBC0634477.1"
                     /translation="MFFQEFEAINSVILPLVIFDLIDRKPIMVIGFGEVCGVDSLVDS
                     GIEVVSLDGLSDLLLVEKLTPLFN"
BASE COUNT         1507 a         1173 c         1204 g         1260 t
ORIGIN      
        1 aatgtgcgta atgacccccc tgacctccaa cccgtcctca tcgtcatcag gtatagccct
       61 gaagttatcc agcttatcga gttcctggag acaccgcttg gggtgtagtc gcaatcgcat
      121 gatcctgaat tcttgttcca ggacacagag caccaaagac ccgtcaacgg gcgtgccccc
      181 aaaatctact atgagcagcg caccaggctt tatcccttcc cggaaagagt aggtatcact
      241 tcgaaaaaag aatactcccg gcgctcctgt attacagtgc tgatcgagtg acagcctgtt
      301 ttcctggtag tcggttgctg gcgatggaaa acccattttt aacggcctcc gttggggtta
      361 aaaagcatga atgtccggtt ctctccttcc tgagtggaaa tgtctttaaa aacggtcacg
      421 taggtttcaa tccactgatt tgcttggcga caactccagt gaaaattaat cagcgcaagc
      481 tggctgacaa aggcttctgt cgtaactgtc tgacgaccgt tcggctcacg cttaatgctc
      541 gcacgccagg ctgagtcaat ttcatagtgt ctaggcatga aaaacctccg atcaatatag
      601 ctgtatgcat atgggtcttc ccttgttgtg gtggctgaag gcatgataat ggtgtattta
      661 atcgccagag gtcaccgcca tggacgaaaa gtccctctac gctcatattc tcaacctgtc
      721 cgatccgtgg caggtaaagt ccctttctct cgatgaaaat gccggttctg ttactgtcac
      781 tattgagatc gctgaaaaca cccggctagc ctgtccgacc tgcggtaaat cctgttctgt
      841 tcacgatcac cgtcatcgta aatggcgcca tcttgatacc tgccagttca ccactattgt
      901 tgaagccgat gttccacgaa ttatgtgtcc ggagcatggc tgcctgacgt tgcctgttcc
      961 gtgggctggc cccggaagcc ggtatacgtt gctattcgaa tcgttcgttc tctcatggct
     1021 gaaaatcagc accgttgatg ctgtcaggaa gcaacttaag ctcagttgga atgcggttga
     1081 cggcattatg acccgggcag ttaagcgagg tcttgcccgg ataaaaaagc cattatccgc
     1141 ccgtcatatg aatgtggatg aggtcgcctt taaaaaagga catcgttaca taacggtgat
     1201 ctccgatcgc gatggtcggg cgctggcctt aacggatgat cgcggcacag agagtcttgc
     1261 cggctatctt cgcacgctca ctgatgggca gttgctggct atcaaaacgc tctcaatgga
     1321 catgaacgcg ggctatataa gagcagcgcg tatccactta cccagtgcgg ttgagaaaat
     1381 cgcctttgac cgcttccatg tggcgaagca actgggcgag gtagttgata aaacccgtca
     1441 gaatgaacat ccgcacctcc ctgttgaaag ccgacaccag gcaaaaggaa cccgcttcct
     1501 gtggcagtac agcgataagt ggatgaccga atcccggcag gaaaagctga tgtggctgcg
     1561 tgcacagatg aagctgacga gccagtgctg ggcgctgaaa gagctggcaa aggatatctg
     1621 gaacaggcca tggagcgagg aaagacggag tgactggcag agatggttgg cgctggcggc
     1681 taacagtgac gttcccatga tgaaaaatgc cgcgaaaacg ataggaaaaa ggctgtacgg
     1741 gatcctgaat gcgatgcgac acagtgtctc aaacggaaat gcggaggcac ttaacagcaa
     1801 gatcaggctg ctgaggataa aagccagggg ataccgaaac cgggagcgct ttaaactggg
     1861 ggtgatgttc cactacggaa agctgaatat ggcgttctga gccttcccac catgatcggg
     1921 gaagacccat gcatatacag tataaagaat cagttttatt cttcaacaca ctgtttatta
     1981 tgttgtaact actccctacc ttcaggttca tggttcattt tgttaacggt ctgttgcttc
     2041 acagctttgc tgatagtcgc ccggctacaa cccagcactt tttgaatctg gctccaggag
     2101 ctgccgctcg caatcagcct gtttatggcg tcatagcgag actgattaac ctggcggcct
     2161 ttatacttcc cttccctttt cgccctggcg atcccctgct gctgccgttc ccggcgctgt
     2221 tcatagtctc gcctggcgac ggcggccagc atatccagca acatatcgtt tatggccgaa
     2281 aacattcggc tgtcaaaatc attgtgaccc gatgcgagcc aggttgtcgg aacgttgacg
     2341 gccacaaccc ggatatcttt ctgccggatc attttcttca gtgtgttcca gtcctcccct
     2401 accaggcgtg aaagcctgtc cacatcctct accagcaaga tatcgttttg ctgacaatct
     2461 ttcaggagcc ggaacaactc agggcgttca agcttagaac ctgattcatt ttcaatgtag
     2521 tagttacaga tgctcaggcc gcgctcgatg gcgaaggtat ttatcgtgtc cagggcgcgt
     2581 gttgcatcct gttcagtcgt ggatgcgcgt aagtaagctc tgacaaagcc tttcggtact
     2641 gtttgagtca ttatagggaa ccagttcatt ttgagttaac cagacacacc catacagtac
     2701 ccatttcagt tggttcaggg aaggcacact caaaaagaac cagcaaacag accccagccc
     2761 tatagtgaca acgtcacact aaaaatttac aacataaaga tgatgtaaag acacaccaag
     2821 atttacacca taaagcgcac ataaagacac agcaacattt accatgtaaa gacaccataa
     2881 agataaatat atctttattt gtgctttaca tggtaaagcc attgcattat aaagacactg
     2941 taaagacaaa agtatcttta cgaaaaacac accatgtaaa gacattcata tctttacatg
     3001 agctttacaa cataaagaga gggattctga aatgggtaaa atcttgcttg tcgtatcaga
     3061 taaaggtggg gtaggcaaaa gcacctacgt ggctaacaca ggctcaatgc tggtcaacaa
     3121 aggtaagtcg gtaattatcc tgaagacaga taaaaaccac gatctgttga gctggaacga
     3181 aaagcggaca gataacggct tactcactat cccggttcac gcagcttacg gaaacgtcag
     3241 caacgaaatt aagcgcctta gtaagctgtg tgaagttctc attgtcgatt gccccggcca
     3301 cgacagccag gagttccgta gcgccctgac agtatcagat atcgtggtga cactggttaa
     3361 gccgtcctct gatttcgaaa gcgaaacact gaccagtgtt acagagaaaa tccgcaccgc
     3421 tcagaaagct aacgcagctc tggaaccgtg ggtgctgttc accagaatca actcagcgaa
     3481 accccgccac agaaaagcgg ccattgatct ggataaatta ctgcgttcgg acaacatctg
     3541 gattcaacct ctgaaaaccc ggatatccga gctggatgtg tatgaaagcg cctgtaatga
     3601 aggggcaggg gtacatgacg ttagccgggc atcgagcctt tcaacagcga aagcacagat
     3661 tgaacttgtg gcacaggaaa ttggcatttt atagaaatat caacaatatt catcgaaatc
     3721 tttacattgt aaatacacca taaagatact atgatattta caattaatgc ataccgtaca
     3781 aggggaaatt ttcatggctt taaaactaaa ccgcccgaac atcgatgaat ctcagcaacc
     3841 agcaacaaac gcagaaaccg cgcgttttat ctccggcgct accagagcgc ctgtagcggg
     3901 taaaccaaag ttgatgaact tcagactgcc agcgtacttt gaggagatcc tggaagcgga
     3961 ggcgcagaga acaggccaga gcaagacaac cgttctaaag gcagcgctgg ccgcattcga
     4021 taacctggac gagaacctga aaaaccactg gctgcttgaa tctgcaaaat tagggtagcg
     4081 ttatggctaa gaaaaagaga tatgttgtga tggttagaga taaaccaaat acagcggcaa
     4141 tcagcgatta ttagcctggt tagtatggtt cgctaacagg cataataagg ccgttgccta
     4201 tgactgcgga gaatggattg tcgaaccatc acattggtta agaattggaa atccaaaata
     4261 gaaagaaacc taaggaaaga aaaatgttca tattcagata tattaaaact cttattaata
     4321 tctacttgtt atacatccaa ccgatattgg ggatgttcct tataggtata ggcttatggg
     4381 ggttctatgc acctgatgag ggaacttgta ctaatctcaa tattgagtta tgcgctgtat
     4441 cagctattga tgttctgaag cctgctattt ttgtattttt aggcattatt accgttgccg
     4501 gatggtactt taccgaactt cagccgaagc taagggggga gggcaagtat atgaaggtaa
     4561 aaacaggtgt aaaaccggaa gatttcgtta agtaaaaacc gagcctaaag acgttaaccg
     4621 tgggggattt atgaataaat catggcttga acaacaggtg caaaatgaaa aattaaaaaa
     4681 agtacaggaa gagaaaaaag atggcactat ccaaaaagga ttgtacaggg ttcgtataaa
     4741 agacaaatac aggtgggatt tgtgggaaaa tgatttcaga gttgttattg cttattcgaa
     4801 agatgatgca gagctaaaat ttacagaaat gacaggtttt aatgagcatt actatataga
     4861 aagcattgaa aaaatagtgc tttcagatat agaaaaaatc ttactggaaa actgaaaaga
     4921 tagttatcca gaggtttagt taaataatgg cgtcagtttt tcaaccagta gcagatcgct
     4981 taaaccgtct aaagaaacaa cttctatacc agaatcaaca agtgaatcaa ctccacatac
     5041 ttcaccgaag ccgataacca taatcggctt tcggtctatc aaatcaaaaa tcaccaaagg
     5101 caatattaca ctgttaatcg cttcaaactc ctgaaaaaac attt
//
LOCUS       DADXDL010000170         5109 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.170, whole genome shotgun sequence.
ACCESSION   DADXDL010000170 DADXDL010000000
VERSION     DADXDL010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5109)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5109)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5109
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.170"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            42..581
                     /locus_tag="IRB70_004661"
     CDS             42..581
                     /locus_tag="IRB70_004661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000290791.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBC0634478.1"
                     /translation="MAVRGINKVILVGRLGKDPEVRYIPNGGAVANLQVATSETWRDK
                     QTGEMREQTEWHRVVLFGKLAEVAGEYLRKGAQVYIEGQLRTRSWEDNGITRYVTEIL
                     VKTTGTMQMLGRAAGAQTQPEEGQQFSGQPQPEPQSEAGTKKGGAKTKGRGRKAAQPE
                     PQPQPPEGEDYGFSDDIPF"
     gene            644..877
                     /locus_tag="IRB70_004662"
     CDS             644..877
                     /locus_tag="IRB70_004662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_958724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HBC0634479.1"
                     /translation="MSEYFRILQGLPDGPFTRKHAEAVAAQYRNVFIEDDHGEQFRLV
                     VRNNGAMVWRTWNFEDGAGYWMNHVIRDFGILK"
     gene            943..2901
                     /locus_tag="IRB70_004663"
     CDS             943..2901
                     /locus_tag="IRB70_004663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBC0634480.1"
                     /translation="MSVTESKAKTERKSSRKPAKTQETVLSALLAQTEEVSVPLASLI
                     KSPLNVRTVPYSVESVSELAESIKGVGLLQNLVVHTLPGDRYGVAAGGRRLAALNMLA
                     ERNILPADWPVRVKVILQELATAASMTENGHRRDMHPAEQIAGFRAMAQEGKTPAQTG
                     DLLGYSPRHVQRMLKLADLAPVILDALAEDRITTEHCQALALENDTARQVQVFEAACQ
                     SGWGGKPDVRVIRNLITESEVAVAGNSKFRFVGADAFSPDELRTDLFSDDEGGYVDCV
                     ALDAALLEKLQAVAEFLREAEGWGWCAGRMEPVGECREDAGTYRCLPEPEAVLTEAEE
                     ERLNELMTRYDALENQCEESDLLEAEMKLMRCMAKVRAWTPEMRAGGGVVVSWRYGNV
                     CVQRGVQLRSEDDVADDADRTEQVQEKASVGGISLPLLTKMSSERTLAVQAALMQQPD
                     KSLALLAWTLCLNVFGSGAYSKPAQISLECKHYSLTSDAPSGKEGVAFMALMAEKARL
                     AALLPEGWSRDMTTFLSLSQEVLLSLLSFCTACSLNGVQTRECGHTSRSPLDSLETAI
                     GFHMRDWWQPTKANFFGHLKKPQIIAALNEAGLSGAARDAEKMKKGDAAEHAEHHMKD
                     NCWVPGWMCAPHPQTDTTERTDNLADAA"
     gene            2956..3390
                     /gene="psiB"
                     /locus_tag="IRB70_004664"
     CDS             2956..3390
                     /gene="psiB"
                     /locus_tag="IRB70_004664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000845953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugation system SOS inhibitor PsiB"
                     /protein_id="HBC0634481.1"
                     /translation="MKTELTLNVLQTMSAQEYEDIRAAGSDERRELTHAVMRELDAPD
                     NWMMNGEYGSEFGGFFPVQVRFTPAHERFHLALCSPGDVSQVWVLVLVNAGGEPFAVV
                     QVQRRFAPEAVSHSLALAASLDAQGYSVSDIIHILMAEGGQA"
     gene            3387..4106
                     /locus_tag="IRB70_004665"
     CDS             3387..4106
                     /locus_tag="IRB70_004665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001763821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid SOS inhibition protein A"
                     /protein_id="HBC0634482.1"
                     /translation="MSARSQALVPLSTEQQAAWRAVAETEKRRHQGNTLAEYPYAGAF
                     FRCLNGSRRISLSDLRFFMPSLTAEELHGNRLQWLYAIDVLIETQGEVCLLPLPGDAA
                     ERLFPSVRFRVRERSRHKSALVMQKYSRQQAREAEQKARAYQALVAQAEIELAFHSPE
                     TVGSWHARWSDRVAEHDLETLFWQWGERFPSLAGMERWQWQDMPFWQVIAEAGMAARV
                     VGHAVREMERWMVPNKLREAA"
     gene            4266..5109
                     /locus_tag="IRB70_004666"
                     /pseudo
     CDS             4266..5109
                     /locus_tag="IRB70_004666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS150 family transposase"
BASE COUNT         1217 a         1285 c         1583 g         1024 t
ORIGIN      
        1 agatgatggg ggctgaaaac atcaacagaa ggaggcacat catggcagtt cgtggcatta
       61 acaaggtcat tctcgtagga cgcctgggaa aagatccgga agtccgttac atccccaacg
      121 ggggcgcagt ggcaaacctg caggtcgcca cgtcggaaac ctggcgtgac aaacagacag
      181 gggagatgcg ggagcagaca gaatggcatc gcgtggtgct gttcggcaag ctcgcggaag
      241 tggctggcga atatctgcgc aagggcgcgc aggtctacat cgaaggtcag cttcgcaccc
      301 gtagctggga agataacggt atcacccgtt acgtcaccga aattcttgtt aagaccacag
      361 gcaccatgca gatgctggga cgtgccgcag gtgctcagac tcagccggaa gaggggcaac
      421 agttcagcgg tcagcctcag ccggaaccac agtcggaggc cggtacgaaa aaaggtggcg
      481 caaaaacgaa aggccgtgga cgtaaggccg cgcagcccga gcctcagccg caaccgccgg
      541 agggggagga ttacgggttt tcagacgata tcccgttctg atcgggctga ctgtgataac
      601 cgccccgccc cgttctgtgc ggggcatcac cggagagatg agaatgagcg aatatttcag
      661 aatacttcag gggctgcctg acggtccttt tacccgcaaa catgccgaag ctgttgccgc
      721 acagtaccgg aacgtcttta tcgaggatga ccacggcgaa cagtttcgcc tggttgtccg
      781 taataacggt gcaatggtct ggcgtacctg gaattttgag gacggtgccg ggtactggat
      841 gaaccatgtc atcagggatt tcgggattct taagtaagag aggtgccgga cggggacacg
      901 tccggcagac aatcattatt accgttttgg gaggtactaa ctatgtcagt tacagagtct
      961 aaggcaaaaa cggagcgtaa atccagccgt aaacctgcaa aaacgcagga aacagtcctg
     1021 tctgccctgc tggcgcagac ggaggaagtg agcgtgccgc tggcctcact gattaaatca
     1081 ccgctgaatg tgcgcacggt gccgtattct gtggagtccg tcagcgaact ggctgagtcc
     1141 attaagggcg ttggcctgtt gcagaatctg gtcgtgcata ccctgcctgg tgaccgttac
     1201 ggtgtcgccg caggtggtcg ccgactggct gcactcaaca tgctggcaga gcgcaacatc
     1261 cttccggctg actggcctgt acgcgtgaag gttattctgc aggaactggc gactgccgca
     1321 tcaatgactg aaaacggtca tcgtcgggat atgcaccctg ccgaacagat tgccggattc
     1381 cgcgcaatgg cgcaggaagg caaaacacct gcgcagactg gcgacctgct gggctattca
     1441 ccccgccacg tccagcgaat gctgaaactg gcagaccttg cacccgtcat ccttgatgcg
     1501 ctggcagaag accgcatcac caccgaacac tgtcaggcgc tggcgctgga gaacgacacc
     1561 gcgcgtcagg tgcaggtgtt tgaagccgcc tgccagtcag gatggggcgg taaaccggat
     1621 gtgcgggtta tccgcaacct gattaccgaa agtgaagtgg cggtggctgg gaacagtaaa
     1681 ttccgcttcg tgggggctga tgccttctcg ccagacgaac tgcgcaccga tttgttcagc
     1741 gacgacgagg gtggctatgt ggactgcgtg gcgctcgatg ccgccctgct ggaaaaactc
     1801 caggctgtcg cagagttcct tcgggaagcc gaaggctggg gatggtgtgc cggacgcatg
     1861 gagcctgtag gtgagtgccg tgaggatgcc ggaacatacc gctgtctgcc ggagccggaa
     1921 gcggtgctga cggaggcgga agaagaacgt ctgaacgaac tgatgacgcg ttacgacgcg
     1981 ctggaaaacc agtgtgagga atctgacctg ctggaagcag aaatgaagct gatgcgctgc
     2041 atggcgaagg tcagagcgtg gacgccggag atgcgtgccg gaggtggagt ggtggtgtcc
     2101 tggcgttatg gcaacgtgtg tgtccagcga ggtgtgcagt tgcgcagtga ggatgacgtg
     2161 gctgacgacg ctgaccgcac ggaacaggtg caggagaaag cgtcagtggg gggaatcagt
     2221 ctgccactgc tgacgaaaat gtcttccgaa cgcacgctgg cagtccaggc ggcgcttatg
     2281 cagcaaccgg acaaatctct ggcactgctg gcatggacgc tctgcctgaa tgtgtttggc
     2341 agcggagcgt acagtaaacc ggcacaaatc agcctggaat gtaaacatta ttcgctgacc
     2401 agcgatgcgc cgtcagggaa ggaaggtgtc gcattcatgg cgctgatggc agaaaaagcc
     2461 cgtcttgctg ccctgttacc ggagggatgg tcacgagaca tgacgacatt cctgtcactc
     2521 agtcaggagg tgctgttgtc cctgctcagt ttctgcaccg catgcagcct taacggtgtc
     2581 cagacccgtg agtgtggtca cacgtcacgc agtccgcttg actcgctgga aaccgctatc
     2641 ggattccaca tgcgcgactg gtggcagccg acaaaagcaa acttcttcgg acacctgaaa
     2701 aagccgcaga ttatcgcagc cctgaatgag gcaggactgt ccggtgctgc acgggatgca
     2761 gagaagatga agaaaggtga tgcggctgaa catgcagagc accatatgaa agacaactgc
     2821 tgggtgcctg gctggatgtg tgcaccacat ccacagacgg ataccactga acgcaccgat
     2881 aacctggctg atgccgcctg ataaacaacc acaccgcccc gccggagacg gggcggcagc
     2941 aagggagata ccgtgatgaa aactgaactg accctgaatg tattacagac catgagcgca
     3001 caggaatatg aagatatccg ggcagccgga agtgatgaac gtcgtgagct gacacacgcc
     3061 gtgatgcggg aactggatgc gccggacaac tggatgatga atggcgagta tggcagtgag
     3121 ttcgggggct ttttccccgt ccaggttcgt ttcacgccag cccacgaacg tttccacctg
     3181 gcgttatgtt caccgggcga tgtctctcag gtctgggtgc tggttctggt gaatgccggt
     3241 ggtgagccgt ttgcggtggt tcaggtacag cggcggtttg caccggaagc cgtcagccat
     3301 tcactggcac tggcggcgtc actggacgcg caggggtaca gcgtcagtga catcatccat
     3361 atcctgatgg cggaaggagg tcaggcatga gcgcacgttc acaggcactg gttcctctca
     3421 gcacagagca acaggccgca tggcgggcgg tggcggagac cgaaaaacgc cgccatcagg
     3481 gtaacacgct ggctgaatat ccgtatgcgg gggcgttttt ccgctgtctg aacggaagcc
     3541 gcaggatatc gctgtctgac ctgcgatttt tcatgccgtc cctgaccgca gaagaactgc
     3601 acggcaaccg tcttcagtgg ctgtatgcca tcgatgtgct gattgaaaca cagggcgagg
     3661 tctgcctcct tccccttccc ggtgatgcag cagagcgctt gttcccgtcg gtgcggtttc
     3721 gtgtcaggga acgcagtcgc cataaatccg cgctggtcat gcagaagtac agccgccagc
     3781 aggcgaggga ggcagagcag aaagcccgtg cgtaccaggc gctggtcgct caggctgaaa
     3841 tcgaactggc attccattcg ccggaaacag tcggaagctg gcatgcacgc tggagtgacc
     3901 gggtggcaga gcatgacctg gaaaccctgt tctggcagtg gggcgagcgt tttccgtcac
     3961 tggccggaat ggaacgctgg cagtggcagg atatgccatt ctggcaggtc atcgcagagg
     4021 ctggtatggc ggcaagggtg gtcggtcatg ctgttcgtga gatggagcgg tggatggtgc
     4081 cgaacaaact ccgggaggca gcgtgatgcg gcaacaatca cacggatttc ccgtgaacgg
     4141 tctgaatgag cggattattt tcagggaaag tgagtgtggt cagcgtgcag gtatatgggc
     4201 tatgatgtgc ccggcgcttg tactgcaccc attttgttgg acgatgaaat ggaatagccc
     4261 ctaatatgtc aaagccaaaa tacccttttg aaaagcgcct tgaagtcgtg aatcactact
     4321 tcacaactga tgatggttac aggatcatct cggcacgttt tggtgtcccc cgaacccagg
     4381 tcaggacatg ggttgccctc tatgaaaaac atggagaaaa aggtttaatt cccaaaccta
     4441 aaggcgttag tgctgatcca gagttgcgta ttaaggtcgt gaaagctgtg atcgagcagc
     4501 acatgtccct taatcaggct gctgctcact ttatgcttgc tggtagtggt tctgtagcca
     4561 ggtggctgaa ggtctatgaa gagcgcggag aagctggttt acgcgcgctc aagattggca
     4621 ccaaaagaaa cattgcaata tcagttgatc cagaaaaagc ggcatcagca ttggagctgt
     4681 caaaagaccg acgcattgag gatcttgaaa ggcaagttcg atttcttgaa acgcggctta
     4741 tgtatctaaa aaagctgaaa gccttagctc atcccacgaa aaagtgaaag tactcaacga
     4801 gctaaggcag ttttatcctc ttgatgagct tctcagggct gcggagatac cgcgcagtac
     4861 gttttattat catctaaagg ctctcagcaa gcctgacaag tatgcggacg ttaaaaagcg
     4921 tattagtgag atttatcacg agaatagagg ccgatacgga taccgtaggg taacgctgtc
     4981 tcttcatcga gaagggaaac agattaacca taaagctgtt cagcgcctga tgggaaccct
     5041 ctcacttaaa gcagcgatta aggtcaagcg ataccgctct tacagaggag aggtagggca
     5101 aaccgcccc
//
LOCUS       DADXDL010000171         5029 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.171, whole genome shotgun sequence.
ACCESSION   DADXDL010000171 DADXDL010000000
VERSION     DADXDL010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 5029)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5029)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5029
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.171"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            221..880
                     /locus_tag="IRB70_004667"
     CDS             221..880
                     /locus_tag="IRB70_004667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011152976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-1 chloramphenicol O-acetyltransferase"
                     /protein_id="HBC0634483.1"
                     /translation="MEKKITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAF
                     LKTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETF
                     SSLWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNV
                     ANMDNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQGG
                     A"
     gene            complement(1081..1458)
                     /locus_tag="IRB70_004668"
     CDS             complement(1081..1458)
                     /locus_tag="IRB70_004668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBC0634484.1"
                     /translation="MKDYLCKKLFNRLSGTLVIRARCGNNITGLACCNILYPSPRYSG
                     QLHIKELYVSQCDRNKGTGKAIMRFIARLALEQECLSLSWNAEKSNPGANRFYQALGG
                     RINDHIVNYYLHGESLSKLASGI"
     gene            complement(1525..4491)
                     /locus_tag="IRB70_004669"
     CDS             complement(1525..4491)
                     /locus_tag="IRB70_004669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element TnAs3 family transposase"
                     /protein_id="HBC0634485.1"
                     /translation="MPRRSILSAAERESLLALPDSKDDLIRHYTFNDTDLSIIRQRRG
                     PANRLGFAVQLCYLRFPGVILGVDELPFPPLLKLVADQLKVGVESWNEYGQREQTRRE
                     HLSELQTVFGFRPFTMSHYRQAVQMLTELAMQTDKGIVLASALIGHLRRQSVILPALN
                     AVERASAEAITRANRRIYDALAEPLADAHRRRLDDLLKRRDNGKTTWLAWLRQSPAKP
                     NSRHMLEHIERLKAWQALDLPTGIERLVHQNRLLKIAREGGQMTPADLAKFEPQRRYA
                     TLVALATEGMATVTDEIIDLHDRILGKLFNAAKNKHQQQFQASGKAINAKVRLYGRIG
                     QALIDAKQSGRDAFAAIEAVMSWDSFAESVTEAQKLAQPDDFDFLHRIGESYATLRRY
                     APEFLAVLKLRAAPAAKNVLDAIEVLRGMNTDNARKLPADAPTGFIKPRWQKLVMTDA
                     GIDRRYYELCALSELKNSLRSGDIWVQGSRQFKDFEDYLVPPEKFTSLKQSSELPLAV
                     ATDCEQYLHERLTLLEAQLATVNRMAAANDLPDAIITESGLKITPLDAAVPDTAQALI
                     DQTAMVLPHVKITELLLEVDEWTGFTRHFTHLKSGDLAKDKNLLLTTILADAINLGLT
                     KMAESCPGTTYAKLAWLQAWHTRDETYSTALAELVNAQFRHPFAGHWGDGTTSSSDGQ
                     NFRTASKAKSTGHINPKYGSSPGRTFYTHISDQYAPFHTKVVNVGLRDSTYVLDGLLY
                     HESDLRIEEHYTDTAGFTDHVFALMHLLGFRFAPRIRDLGDTKLYIPKGDAAYDALKP
                     MIGGTLNIKHVRAHWDEILRLATSIKQGTVTASLMLRKLGSYPRQNGLAVALRELGRI
                     ERTLFILDWLQSVELRRRVHAGLNKGEARNALARAVFFNRLGEIRDRSFEQQRYRASG
                     LNLVTAAIVLWNTVYLERAAHALRGNGHAVDDSLLQYLSPLGWEHINLTGDYLWRSSA
                     KIGAGKFRPLRPLQPA"
     gene            complement(4494..4991)
                     /locus_tag="IRB70_004670"
     CDS             complement(4494..4991)
                     /locus_tag="IRB70_004670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001774155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBC0634486.1"
                     /translation="MEGVKVDRAFSDKASGKDVKRPQLEALISFARTGDTVVVHSMDR
                     LARNLDDLRRIVQTLTQRGVHIEFVKEHLSFTGEDSPMANLMLSVMGAFAEFERALIR
                     ERQREGIALAKQRGAYRGRKKSLSSERIAELRQRVEAGEQKTKLAREFGISRETLYQY
                     LRTDQ"
BASE COUNT         1002 a         1373 c         1519 g         1135 t
ORIGIN      
        1 cgcactttgc gccgaataaa tacctgtgac ggaagatcac ttcgcagaat aaataaatcc
       61 tggtgtccct gttgataccg ggaagccctg ggccaacttt tggcgaaaat gagacgttga
      121 tcggcacgta agaggttcca actttcacca taatgaaata agatcactac cgggcgtatt
      181 ttttgagtta tcgagatttt caggagctaa ggaagctaaa atggagaaaa aaatcactgg
      241 atataccacc gttgatatat cccaatggca tcgtaaagaa cattttgagg catttcagtc
      301 agttgctcaa tgtacctata accagaccgt tcagctggat attacggcct ttttaaagac
      361 cgtaaagaaa aataagcaca agttttatcc ggcctttatt cacattcttg cccgcctgat
      421 gaatgctcat ccggaattcc gtatggcaat gaaagacggt gagctggtga tatgggatag
      481 tgttcaccct tgttacaccg ttttccatga gcaaactgaa acgttttcat cgctctggag
      541 tgaataccac gacgatttcc ggcagtttct acacatatat tcgcaagatg tggcgtgtta
      601 cggtgaaaac ctggcctatt tccctaaagg gtttattgag aatatgtttt tcgtctcagc
      661 caatccctgg gtgagtttca ccagttttga tttaaacgtg gccaatatgg acaacttctt
      721 cgcccccgtt ttcaccatgg gcaaatatta tacgcaaggc gacaaggtgc tgatgccgct
      781 ggcgattcag gttcatcatg ccgtttgtga tggcttccat gtcggcagaa tgcttaatga
      841 attacaacag tactgcgatg agtggcaggg cggggcgtaa tttttttaag gcagttattg
      901 gtgcccttaa acgcctggtt gctacgcctg aataagtgat aataagcgga tgaatggcag
      961 aaattcgaaa gcaaattcga cccggtcgtc ggttcagggc agggtcgtta aatagccgct
     1021 tatgtctatt gctggtttac cggtttattg actaccggaa gcagtgtgac cgtgtgcttc
     1081 tcaaatgcct gaggccagtt tgctcaggct ctccccgtgg aggtaataat tgacgatatg
     1141 atcatttatt ctgcctccca gagcctgata aaaacggtta gcgccggggt tggatttttc
     1201 agcgttccag ctaaggctaa ggcattcctg ttcaagcgca agccgggcta taaagcgcat
     1261 tatcgcttta cccgtgccct tatttcgatc gcactgagaa acatacagct ctttaatatg
     1321 cagctgaccg ctgtatcggg gcgagggata aagaatattg caacatgcca ggccagtaat
     1381 gttattgccg cagcgcgctc tgatcaccag ggtaccggaa agccggttga ataacttttt
     1441 acagagataa tccttcatca acgcttcctg aatgatacct tcgccataat aggggtcgtc
     1501 tcagaaaacg gaaaataaag cacgctaagc cggttgcaga ggccgtagcg gcctgaactt
     1561 ccccgcgccg atcttggcgc tgctgcgcca taggtaatca ccggtcaggt tgatgtgctc
     1621 ccagccgagt ggcgacaggt actgcaatag cgagtcatcg acggcatgac cattgccgcg
     1681 caacgcatgc gccgcacgct ccaggtagac cgtgttccac agcacgatgg ccgccgtcac
     1741 caggttgagg ccgctggccc ggtagcgctg ctgctcgaaa ctgcggtcac ggatttcacc
     1801 aaggcggttg aagaacacgg cacgggccag cgcattgcgc gcctcgccct tgttcagccc
     1861 ggcatgcacg cggcggcgta gctcgacgct ttgcagccag tcgaggatga acagcgtgcg
     1921 ctcgatgcgg cccaactcgc gcagcgcgac ggccaagccg ttctggcgcg ggtagctgcc
     1981 gagtttcctg agcatcagcg aggccgtcac cgtgccctgc ttgatcgagg tggccagccg
     2041 caggatttcg tcccaatggg cgcggacgtg cttgatgttg agcgtgccgc cgatcatcgg
     2101 cttgagcgcg tcataggcgg catcgccctt cgggatgtag agcttggtgt cgcccaggtc
     2161 gcggatgcgc ggcgcgaagc ggaagcccaa gaggtgcatc agggcgaaga cgtgatcggt
     2221 gaagcccgcc gtgtcggtgt agtgctcctc gatccgcagg tcggattcgt ggtacagcag
     2281 gccgtcgagc acgtaggttg agtcgcgcag gccgacattg accaccttgg tgtggaatgg
     2341 cgcgtattgg tcggagatgt gggtgtagaa agtccgtcct gggctgctgc catattttgg
     2401 gttgatgtgc cccgtgctct ttgccttgct agcggttcgg aaattctgtc cgtccgatga
     2461 tgatgtggtg ccatcgcccc agtgcccggc aaagggatgc cgaaactgag cgttgaccag
     2521 ttcagccaac gctgtcgagt acgtttcgtc gcgggtatgc caggcttgca gccaagcgag
     2581 cttcgcgtag gtcgtgccgg ggcaggactc ggccatcttg gtcaggccca ggttgatcgc
     2641 gtcggccagg atcgtggtca acaacaggtt cttgtccttg gccagatcgc ccgatttcaa
     2701 gtgcgtgaag tgccgggtga agcccgtcca ctcatcgact tcgagcagca gttcggtgat
     2761 cttgacgtgc ggcaggacca tggctgtctg gtctatcagc gcctgcgcgg tgtcgggcac
     2821 cgccgcatcc agcggcgtga tcttcaagcc cgactcggtg atgatggcat ccggcaggtc
     2881 gttggctgcc gccatgcggt tgacggtggc aagttgtgct tccagcagcg tcagccgctc
     2941 atgcagatat tgttcgcagt cggtggccac ggccagcggc aattcgctgg actgcttgag
     3001 gctggtgaac ttctcgggcg gtaccaggta gtcctcgaag tccttgaact ggcgtgaacc
     3061 ctgcacccag atgtcgcccg agcgcaggga gttcttcaac tcggacagcg cgcacagttc
     3121 gtagtagcgc cggtcgatgc cggcgtcggt catcaccagt ttctgccagc gcggcttgat
     3181 gaagccggtc ggtgcatcgg ctggcagctt gcgggcgttg tcggtgttca tgccgcgcag
     3241 cacctcaatg gcatcaagca cgtttttggc ggcgggcgcg gcccgcagct tgagcacggc
     3301 aaggaattcc ggtgcatagc ggcgcagggt ggcgtagctc tcgccgatgc gatgcaggaa
     3361 atcgaagtca tcgggttgcg cgagcttctg cgcctcggtg acgctctcgg caaaggaatc
     3421 ccaggacatg acggcctcga tggcggcaaa cgcatcgcgg cctgattgct tggcgtcgat
     3481 cagcgcctga ccgatgcgcc cgtacagacg taccttggcg ttgatggcct tgcctgacgc
     3541 ctggaactgc tgctgatgct tattcttggc agcgttaaac agcttaccca ggatgcggtc
     3601 gtgcaggtcg atgatttcgt cggtgacggt ggccatgccc tcggtggcca gcgccacgag
     3661 agtggcgtag cgccgttgcg gctcgaattt ggccaggtcg gcgggtgtca tctggccgcc
     3721 ctcgcgggca atcttgagca ggcggttctg gtgaaccagc cgctcgatgc cggtaggcag
     3781 atcgagtgcc tgccatgcct tgaggcgttc gatgtgttcc agcatatgcc gcgaatttgg
     3841 cttggccgga gactggcgca accaagccaa ccaggtcgtc ttgccgttgt cccggcgctt
     3901 gagcagatcg tcgaggcggc ggcgatgcgc gtccgccagt ggttcggcca aggcgtcgta
     3961 gatgcgccgg ttagcacggg tgatcgcctc ggcactcgcc cgctcgacgg cgttgagggc
     4021 gggcagaatg accgactgcc gccgcaggtg cccgatcaag gcgctggcca gcacgatgcc
     4081 tttgtcggtt tgcatcgcca gctcggtcag catctggacg gcctgccggt aatggctcat
     4141 ggtgaagggc cggaaaccga acacggtttg cagctcgctc aggtgctcgc gccgggtctg
     4201 ctcccgctgg ccgtactcgt tccagctttc gacgccgacc ttgagctggt cggcgaccag
     4261 cttcaacaag ggcgggaacg gtagttcatc gacgcccagg atgacgccgg gaaagcgcag
     4321 gtaacagagc tgcaccgcga agcccagccg attggctggc ccgcgccgct gtcggatgat
     4381 cgagaggtcg gtatcgttga atgtgtaatg tcggatcagg tcgtccttgg agtccggcaa
     4441 cgccagcagg ctttcccgct cggcggcgga caggatggaa cgacgtggca tatttactga
     4501 tccgttctca agtattgata cagggtttcg cgactgattc cgaattcacg agcaagcttg
     4561 gtcttttgct cgccagcctc gacacgttgg cgcagttcgg caatacgctc agacgacagg
     4621 gatttcttcc tgccacggta agccccgcgt tgcttggcga gcgcaatacc ctcgcgctga
     4681 cgctcgcgga tcagggcgcg ctcgaactcg gcgaacgcgc ccatcaccga gagcatcagg
     4741 ttcgccatcg gagagtcttc gccagtaaaa ctgaggtgtt ccttgacgaa ttcgatatgc
     4801 acgccgcgtt gtgtcagcgt ttgcacgatc cggcgcaaat catcgagatt gcgcgccagg
     4861 cgatccatgc tatgcaccac cacggtgtcg ccggtgcggg cgaagcttat cagcgcttcc
     4921 agttgcggac gcttgacatc cttgccggat gccttgtcgc taaaagcgcg atcaaccttg
     4981 acgccttcca gttgccgttc cgggttctgg tcgaaggtgc tgaccctga
//
LOCUS       DADXDL010000172         4982 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.172, whole genome shotgun sequence.
ACCESSION   DADXDL010000172 DADXDL010000000
VERSION     DADXDL010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4982)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4982)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4982
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.172"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(64..822)
                     /locus_tag="IRB70_004671"
     CDS             complement(64..822)
                     /locus_tag="IRB70_004671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBC0634487.1"
                     /translation="MSQILLQPANAMITLENVNKWYGQFHVLKNINLTVQPGERIVLC
                     GPSGSGKSTTIRCINHLEEHQQGRIVVDGIELNEDIRNIERVRQEVGMVFQHFNLFPH
                     LTVLQNCTLAPIWVRKMPKKEAEALAMHYLERVRIAEHAHKFPGQISGGQQQRVAIAR
                     SLCMKPKIMLFDEPTSALDPEMVKEVLDTMIGLAQSGMTMLCVTHEMGFARTVADRVI
                     FMDRGEIVEQAAPDEFFAHPKSERTRAFLSQVIH"
     gene            complement(830..1933)
                     /locus_tag="IRB70_004672"
     CDS             complement(830..1933)
                     /locus_tag="IRB70_004672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709065.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBC0634488.1"
                     /translation="MTKVLLSHPPRPASHNSSRAMVWVRKNLFSSWSNSLLTIGCIWL
                     MWELIPPLLNWAFLQANWVGSTRADCTKAGACWVFIHERFGQFMYGLYPHDQRWRINL
                     ALLIGLVSIAPMFWKILPHRGRYIAVWAVIYPLIVWWLMYGGFLGLERVETRQWGGLT
                     LTLIIASVGIAGALPWGILLALGRRSHMPIVRILSVIFIEFWRGVPLITVLFMSSVML
                     PLFMAEGTSIDKLIRALVGVILFQSAYVAEVVRGGLQALPKGQYEAAESLALGYWKTQ
                     GLVILPQALKLVIPGLVNTIIALFKDTSLVIIIGLFDLFSSVQQATVDPAWLGMSTEG
                     YVFAALIYWIFCFSMSRYSQHLEKRFNTGRTPH"
     gene            complement(1943..3124)
                     /locus_tag="IRB70_004673"
     CDS             complement(1943..3124)
                     /locus_tag="IRB70_004673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBC0634489.1"
                     /translation="MSHRRSTVKGSLSFANPTVRAWLFQILAVVAVVGIVGWLFHNTV
                     TNLSNRGITSGFAFLDRGAGFGIVQHLIDYQQGDTYGRVFIVGLLNTLLVSALCIVFA
                     SVLGFFIGLARLSDNWLLRKLSTIYIEIFRNIPPLLQIFFWYFAVLRNLPGPRQAVSA
                     FELAFLSNRGLYIPSPQLGDGFIAFILTVVIAIALSVGLFRFNKTYQIKTGQLRRTWS
                     VAVMLIIGLPLLAQWLFGAALHWDVPALRGFNFRGGMVLIPELAALTLALSVYTSAFI
                     AEIIRAGIQAVPYGQHEAARSLGLPNPVTLRQVIIPQALRVIIPPLTSQYLNIVKNSS
                     LAAAIGYPDMVSLFAGTVLNQTGQAIETIAMTMSVYLIISLTISLLMNIYNRRIAIVE
                     R"
     gene            complement(3192..4217)
                     /locus_tag="IRB70_004674"
     CDS             complement(3192..4217)
                     /locus_tag="IRB70_004674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005121390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBC0634490.1"
                     /translation="MKKMMIATLAAASVLLAVANQAHAGATLDAVQKKGFVQCGISDG
                     LPGFSYADADGKFSGIDVDVCRGVAAAVFGDDTKVKYTPLTAKERFTALQSGEVDLLS
                     RNTTWTSSRDAGMGMAFTGVTYYDGIGFLTHDKAGLKSAKELDGATVCIQAGTDTELN
                     VADYFKANNMKYTPVTFDRSDESAKALESGRCDTLASDQSQLYALRIKLSNPAEWIVL
                     PEVISKEPLGPVVRRGDDEWFSIVRWTLFAMLNAEEMGINSQNVDEKAANPATPDMAH
                     LLGKEGDYGKDLKLDNKWAYNIIKQVGNYSEIFERNVGSESPLKIKRGQNNLWNNGGI
                     QYAPPVR"
     gene            complement(4648..4869)
                     /locus_tag="IRB70_004675"
     CDS             complement(4648..4869)
                     /locus_tag="IRB70_004675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634491.1"
                     /translation="MKRLIPVALLTALLAGCAHDSPCVPVYDDQGRLVHTNTCMKGTT
                     QDNWETAGAIAGGAAAVAGLTMGIIALSK"
BASE COUNT         1386 a         1299 c         1152 g         1145 t
ORIGIN      
        1 catcaaatca agcgaaaggc catccgaaag gatggccttt ttgcttttcg aactaacatt
       61 caattaatgg atcacctgcg ataaaaatgc cctcgtacgc tctgacttag gatgcgcaaa
      121 aaactcatcc ggtgcagctt gctccactat ttccccacga tccataaaaa tcacccggtc
      181 agcgacggtt cgtgcaaacc ccatctcatg tgttacacac agcattgtca tacccgactg
      241 cgccagccca atcatcgtat ccagcacctc tttcaccatc tcaggatcga gcgccgacgt
      301 tggctcatca aataacataa ttttcggctt catacacagc gaacgcgcaa tggcaacgcg
      361 ttgctgctga ccacctgaaa tctgtccggg aaacttatgc gcatgttcgg caattctcac
      421 ccgctcaagg taatgcatcg ccagagcttc tgcctctttc tttggcatct tgcgtaccca
      481 aatcggtgcc agggtacagt tctgtagaac ggtcagatga gggaagagat tgaaatgctg
      541 aaagaccatt cccacttcct gcctgacgcg ctcaatattg cgaatatctt cgttaagctc
      601 gatgccatct accacgatcc gtccctgttg gtgttcttcc agatgattaa tacaacgaat
      661 ggttgtcgat ttaccggaac cagaagggcc acacagaacg atccgttctc ccggttgcac
      721 ggttaaattt atatttttca aaacatggaa ttgcccatac catttattga cgttttccag
      781 cgtaatcatc gcgttagcag gttgcagtaa aatttggctc atagtgtcct caatgcggtg
      841 tacgcccggt gttaaaacgt ttttccagat gttggctata acgtgacatg ctgaaacaga
      901 agatccagta gatcagtgct gcgaaaacat acccttccgt cgacataccc aaccaggcgg
      961 gatcaacggt tgcctgctga acgctactga aaagatcgaa caacccgatg atgatcacca
     1021 ggctggtatc tttgaaaagt gcgatgatgg tatttaccag cccaggaatc accagcttca
     1081 acgcctgtgg cagaataacc agcccctggg ttttccagta acccaacgcc agcgactctg
     1141 ccgcttcata ttgcccttta ggcagcgcct gtaatccgcc tcgcacgact tccgcaacat
     1201 atgctgactg aaacaggatc acgccaacca gcgcgcggat caatttgtcg atactggtgc
     1261 cttctgccat aaacaacggc agcatgaccg aagacataaa cagaacggta atcagcggta
     1321 caccgcgcca gaactcgata aaaatgaccg ataagatacg cacaatcggc atatgggagc
     1381 ggcgacctaa cgccagtaag atcccccacg gcagcgcccc cgcaatccca actgatgcaa
     1441 taattaaagt tagcgtcagc ccgccccatt gccgggtttc aacccgctca agaccaagaa
     1501 acccgccata catcagccac cagacaatca gtgggtaaat caccgcccat accgcaatat
     1561 agcgaccgcg atgcgggagt attttccaga acattggtgc gatcgataca agcccaatca
     1621 gtaatgccag gttaattcgc cagcgttggt cgtgtgggta aagcccatac ataaactgac
     1681 caaatcgttc gtggatgaag acccaacagg caccggcttt tgtgcagtcg gcacgcgttg
     1741 agccaaccca gttagcctgc aaaaatgccc agttcagcaa cggtgggatc agttcccaca
     1801 tcaaccatat gcagccaata gtcagcaggc tattgctcca gctggagaat agattttttc
     1861 gcacccacac catcgcgcgg cttgagttat ggctcgccgg gcgcggggga tgagacagca
     1921 atacttttgt catcatgact ccttagcgtt caacgatcgc gatgcggcgg ttatagatat
     1981 tcatcagcag cgagatagtc aggctgataa tcagatagac cgacatggtc atggctatcg
     2041 tctcgatggc ttgccccgtc tggttcagca cggtgccagc aaacagcgaa accatatccg
     2101 gatagccaat agcggcggca agagaggagt ttttgacgat gttgagatac tggctggtta
     2161 acggcggaat aatcactcgc agtgcctggg gaataatgac ctggcgtagc gtaaccgggt
     2221 tgggtaatcc cagtgaccgt gccgcttcat gttgaccata aggcactgcc tggatcccag
     2281 cgcggataat ctcggcgata aatgcagagg tataaaccga aagtgccagc gttaaggctg
     2341 ccagttcagg aattaaaacc atcccgccac ggaagttaaa gcctcgtagg gctggaacat
     2401 cccagtgtag tgctgcgcca aaaagccatt gcgccagtaa aggcaaacct atgatcaaca
     2461 taacggcgac cgaccaggtt cggcgcaatt gtccggtctt tatctggtac gttttattaa
     2521 aacggaatag tccaacagaa agggctatag caataacaac agtcaggata aatgcaataa
     2581 atccgtctcc cagctgcggc gacggaatat aaagcccacg attgctcaaa aaggccagct
     2641 caaacgcact cactgcctgg cgtggtccgg gcaaattgcg caacacggca aagtaccaga
     2701 agaagatttg cagcagcggc ggaatattac ggaagatctc aatataaatt gtggaaagct
     2761 ttcgtagcag ccagttatcc gaaagtcgcg ccagaccgat aaagaagccc agaacagaag
     2821 cgaatacaat acacaatgca gaaaccagta gcgtattgag taagccaaca atgaaaacgc
     2881 gtccgtaggt atcaccctgc tggtaatcga tcaaatgctg gacaataccg aagccagcgc
     2941 cgcgatccag aaaggcaaaa cctgaagtaa tgccacgatt actgagattc gtcacagtgt
     3001 tgtgaaatag ccaaccaaca atgccaacaa cagcaacaac ggcaaggatc tggaataacc
     3061 aggcgcgaac cgtagggttg gcaaaggaga gtgagccttt aacggttgag cggcgatgag
     3121 acatagaaac ctcggaaagc ataacgctga agagagcgcc gccgtagcga cgctcgttac
     3181 ctcacaccga cttaacgcac gggcggcgcg tactgaattc cgccgttatt ccagagatta
     3241 ttttgcccac gtttaatttt cagcgggctt tctgaaccta cgttacgctc aaaaatttcc
     3301 gagtagttac ccacctgttt gatgatgttg taagcccatt tattatccag cttcagatcc
     3361 ttgccgtaat cgccttcttt acccagcaga tgtgccatat caggcgttgc cggattagcc
     3421 gctttttcat cgacgttctg ggaattgatg cccatctctt cagcattcag catggcgaaa
     3481 agcgtccagc gtacaatcga gaaccattca tcatcgccac gacgaactac cggcccaagc
     3541 ggttctttgg agataacttc cggtaagaca atccattcag ccgggttgct taatttgatg
     3601 cgcagggcat acagttgtga ttgatccgag gccagcgtat cgcagcgacc agattccagt
     3661 gccttcgctg attcgtcaga gcgatcgaaa gtcactggtg tgtacttcat attgtttgcc
     3721 ttaaagtaat cggcaacgtt gagttcggta tcagtacccg cctgaataca gacggtagcg
     3781 ccatccagtt ctttcgcgct ttttagtccc gctttatcgt gagtcaggaa gccaatgccg
     3841 tcgtaataag tgacgccggt aaatgccatt cccatcccgg catcgcgaga tgaagtccag
     3901 gtcgtattac gggagagcaa atccacctcc cctgactgta aagccgtgaa gcgttctttt
     3961 gcagtgagcg gggtatattt cactttcgtg tcgtcaccaa atacagctgc cgcaacacca
     4021 cgacaaacat ctacatcaat acctgaaaac ttaccgtcag catcggcata agagaaccca
     4081 ggtaatccat cactgatccc gcattgcaca aaaccttttt tctgaacggc atcaagcgtc
     4141 gcgccagcat gcgcctgatt tgcaacggca agcagcacgc tggcggcagc cagtgtggct
     4201 atcatcatct ttttcataat gcttcctgtg aggcgaaaat tatcgttata ggacgtttgg
     4261 gaaacgtctt ttacctgtct gtggccatcc tcttataagc aaaagtagtg ccagcttttg
     4321 cgcacgattt cgcgtcgcaa taagctgagt gtagacagga aataataaaa acagcgcccc
     4381 gcaatggtgc gaaaatgaaa catgcgccac attttggcgc aaaatattca cacatttttt
     4441 actaagcaga ataatgattg ttagcgtgag tatatttctg gtaggaagtg tgaaaattaa
     4501 attgatgcgt tatttcgaaa gcagcgaaat aacgcgatat aacatgctaa atcagcaggg
     4561 aattacccag cagaatatag caatatttta tcttatggag agatactgta tcgttaaaca
     4621 gagcgcggta ctccgcgccc tgttcagtta tttcgacaga gcgatgatcc ccatcgtcag
     4681 gccagcaaca gctgctgccc cgccagcaat agccccagcc gtttcccagt tatcctgagt
     4741 cgtgcctttc atacaggtat tggtgtgaac cagtcgaccc tgatcatcat aaaccggaac
     4801 gcagggcgaa tcgtgagcac agcccgccag caatgcggtg agcaatgcca caggaattaa
     4861 tcttttcatg gtgttacctc agtaataaac gctaacgctt aataagttaa ctctcttatt
     4921 aacgagctga atgccatttt atcaccggag gttataaatc ttgcggaatg aataatgaca
     4981 aa
//
LOCUS       DADXDL010000173         4960 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.173, whole genome shotgun sequence.
ACCESSION   DADXDL010000173 DADXDL010000000
VERSION     DADXDL010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4960)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4960)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4960
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.173"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            394..2544
                     /gene="btsT"
                     /locus_tag="IRB70_004676"
     CDS             394..2544
                     /gene="btsT"
                     /locus_tag="IRB70_004676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418774.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate/proton symporter BtsT"
                     /protein_id="HBC0634492.1"
                     /translation="MDTKKIFKHIPWVILGIIGAFCLAVVALRRGEHVSALWIVVASV
                     SVYLVAYRYYSLYIAQKVMKLDPTRATPAVINNDGLNYVPTNRYVLFGHHFAAIAGAG
                     PLVGPVLAAQMGYLPGTLWLLAGVVLAGAVQDFMVLFISSRRNGASLGEMIKEEMGPV
                     PGTIALFGCFLIMIIILAVLALIVVKALAESPWGVFTVCSTVPIALFMGIYMRFIRPG
                     RVGEVSVIGIVLLVASIYFGGVIAHDPYWGPALTFKDTTITFALIGYAFVSALLPVWL
                     ILAPRDYLATFLKIGVIVGLALGIVVLNPELKMPAMTQYIDGTGPLWKGALFPFLFIT
                     IACGAVSGFHALISSGTTPKLLANETDARFIGYGAMLMESFVAIMALVAASIIEPGLY
                     FAMNTPPAGLGITMPNLHEMGGENAPIIMAQLKDVTAHAAATVSSWGFVISPEQILQT
                     AKDIGEPSVLNRAGGAPTLAVGIAHVFHKVLPMADMGFWYHFGILFEALFILTALDAG
                     TRSGRFMLQDLLGNFIPFLKKTDSLVAGIIGTAGCVGLWGYLLYQGVVDPLGGVKSLW
                     PLFGISNQMLAAVALVLGTVVLIKMKRTQYIWVTVVPAVWLLICTTWALGLKLFSTNP
                     QMEGFFYMASQYKEKIANGTDLTAQQIANMNHIVVNNYTNAGLSILFLIVVYSIIFYG
                     FKTWLAVRNSDKRTDKETPYVPIPEGGVKISSHH"
     gene            2594..2797
                     /locus_tag="IRB70_004677"
     CDS             2594..2797
                     /locus_tag="IRB70_004677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbdD/YjiX family protein"
                     /protein_id="HBC0634493.1"
                     /translation="MFGNLGQAKKYLGQAAKMLIGIPDYDNYVEHMKTNHPDKPYMSY
                     EEFFRERQNARYGGDGKGGMRCC"
     gene            2808..3764
                     /gene="yjiA"
                     /locus_tag="IRB70_004678"
     CDS             2808..3764
                     /gene="yjiA"
                     /locus_tag="IRB70_004678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313338.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase"
                     /protein_id="HBC0634494.1"
                     /translation="MNPIAVTLLTGFLGAGKTTLLRHILNEQHGYKIAVIENEFGEVS
                     VDDQLIGDRATQIKTLTNGCICCSRSNELEDALLDLLDNLDKGNIQFDRLVIECTGMA
                     DPGPIIQTFFSHEILCQRYLLDGVIALVDAVHADEQMNQFTIAQSQVGYADRILLTKT
                     DVAGEAEKLRERLARINARAPVYTVTHGDIDLGLLFNTNGFMLEENVVSTKPRFHFIT
                     DKQNDISSIVVELDYPVDISEVSRVMENLLLESADKLLRYKGMLWIDGEPNRLLFQGV
                     QRLYSADWDRPWGDEKPHSTMVFIGIQLPEEEIRAAFAGLRK"
     gene            complement(3798..4100)
                     /locus_tag="IRB70_004679"
     CDS             complement(3798..4100)
                     /locus_tag="IRB70_004679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnA antitoxin family protein"
                     /protein_id="HBC0634495.1"
                     /translation="MSMVKHKRGTSSTLDVQHEAELKALANKSDEDIDYSDIPPSSDE
                     QWSNAERGKFYRPLKTQASVRIDADVMEWLKRPGKGYQTRLNAILREAMLRDQNKK"
     gene            complement(4087..4374)
                     /locus_tag="IRB70_004680"
     CDS             complement(4087..4374)
                     /locus_tag="IRB70_004680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_463387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BrnT family toxin"
                     /protein_id="HBC0634496.1"
                     /translation="MPMEFEWDENKAKSNRVKHGIRFEDAVLLFDDPQHLSQQERIEN
                     GEYRWQTIGLVYGIVVILVAHTIRFESGNEIIRIISARKADRKERNRYEHG"
     gene            complement(4573..4960)
                     /locus_tag="IRB70_004681"
                     /pseudo
     CDS             complement(4573..4960)
                     /locus_tag="IRB70_004681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     N-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS1 family transposase"
BASE COUNT         1118 a         1328 c         1250 g         1264 t
ORIGIN      
        1 ttgatacgtt ttaacatggt ttctctttcc tgtggaccga tgcaagattt tcggcctgga
       61 aaggaaaaac tttatgaata tcccgcggag attacgccga gtaattttat tcacactctg
      121 aatttaaaaa gccattattt acataaatta ttcacaatat aaatatgtga tatgaatcac
      181 atatttatcg tcacttaaac gacgcctttg ccgctcaacc gcaaaactga ccgcttacat
      241 ccctaaaata accactcagt tatttacctt actttacgcg cgcgtaactc tggcaacatc
      301 actacaggat agcggtcaat ttacctcctc aaacgcaacg caaacctaga acggcttcgg
      361 ccaactatta atcaatacat gccaggtttt actatggata ctaaaaagat attcaagcac
      421 ataccctggg tgattctcgg aatcatcggt gcattctgcc tcgcggtagt tgcattacgt
      481 cggggggagc acgtcagcgc cctgtggatc gtggtcgcct ctgtgtcggt gtatctggtg
      541 gcgtatcgct actacagtct gtacatcgcc cagaaggtga tgaaactcga ccccacgcgc
      601 gcgacgcctg cggttattaa caacgacggt ctgaactacg ttccgaccaa ccgttacgtg
      661 ttgtttggtc accacttcgc cgctatcgcc ggtgctggtc cgctggtggg tccggttctc
      721 gccgcgcaga tgggctacct gcctggcacg ctgtggctgc tggcgggggt cgtgctggcc
      781 ggtgcggttc aggactttat ggtgctgttt atctcctctc gccgtaatgg cgcatctctt
      841 ggtgagatga tcaaagaaga gatgggacca gtaccgggga ctatcgcgct gtttggctgt
      901 ttcttaatca tgatcatcat cctcgccgtc ctggcgctga ttgtggttaa agccctggcc
      961 gaaagtccgt ggggtgtctt caccgtttgc tcaaccgtac cgattgcgct gtttatgggt
     1021 atctacatgc gctttattcg tccggggcgt gtgggtgaag tctctgtcat tggtatcgtg
     1081 ctgctggttg cctctatcta cttcggtggc gtgattgctc acgatccgta ctggggtccg
     1141 gcactgacct ttaaagacac caccattacc ttcgcgctga ttggctatgc gtttgtttcc
     1201 gcactgctgc cagtgtggct gatcctcgca ccgcgcgact atctggcaac cttcctgaaa
     1261 atcggcgtta tcgtcggcct ggcgctgggt atcgtggtgc tgaacccgga actgaaaatg
     1321 cctgccatga cccagtacat tgacggtact ggcccgctgt ggaaaggcgc tctgttcccg
     1381 ttcctgttca tcaccatcgc ctgtggtgcg gtatctggct tccacgcgct gatctcttcc
     1441 ggtacgacgc caaaactgct ggctaatgaa accgacgcgc gtttcatcgg ctacggcgca
     1501 atgctgatgg agtccttcgt ggcgattatg gcgctggttg ctgcgtccat catcgaaccg
     1561 ggtctttact tcgcgatgaa caccccgcct gctggccttg gcatcaccat gcctaacctg
     1621 catgaaatgg gtggcgagaa cgcgccgatc atcatggcgc agctgaaaga cgttaccgca
     1681 cacgcggcag cgaccgtcag ctcctggggc ttcgtgattt cgccagagca gatcctgcaa
     1741 accgcgaaag acattggtga gccttctgtc ctgaaccgtg caggtggtgc gccgacgctg
     1801 gcggtaggta tcgctcacgt gttccacaaa gtgctgccga tggctgacat gggcttctgg
     1861 tatcacttcg gtattctgtt cgaagcactg ttcatcctga ccgcgctgga tgcgggtacc
     1921 cgttctggcc gctttatgct gcaagacctg ctgggtaact tcatcccgtt cctgaaaaaa
     1981 accgactctc tggttgccgg tatcatcggt actgcgggct gtgtgggtct gtggggctac
     2041 ctgctgtatc agggcgtggt cgatccgctg ggcggcgtta agagcctgtg gccgctgttc
     2101 ggtatttcca accagatgct ggcagccgta gcgctggtac tgggcaccgt tgtgctgatt
     2161 aagatgaagc gcacccaata catctgggta actgttgttc cggctgtatg gctgcttatc
     2221 tgcaccacct gggcgctggg cctgaaactg ttcagcacca acccgcagat ggaaggcttc
     2281 ttctacatgg caagccagta caaagagaag attgctaacg gtactgacct gacggcgcag
     2341 cagattgcca acatgaacca catcgttgtg aacaactaca ccaacgcagg tctgagtatt
     2401 ctgttcctga ttgtggtgta cagcatcatc ttctacggtt tcaaaacctg gcttgcggtg
     2461 cgtaacagcg acaaacgtac tgacaaagaa acaccgtacg ttccaatccc ggaaggcggc
     2521 gtgaagatct cttcgcacca ctaaccgtgt ttagccccgc ttcggcgggg ctttgttctt
     2581 atcagagtga actatgtttg gtaacttagg acaggcaaaa aaatatctcg gccaggcggc
     2641 gaagatgttg attggcattc cagactacga caactacgtc gagcatatga agaccaacca
     2701 tcccgacaag ccgtacatga gctatgaaga attcttccgc gaacgccaga acgcacgcta
     2761 cggcggcgat ggtaaaggcg gtatgcgctg ttgttaatgg agagagcatg aacccgattg
     2821 cagttaccct actcaccggt tttttaggcg cgggcaaaac caccctgctg cgccatattc
     2881 ttaacgaaca acacggctac aagattgccg tgattgaaaa cgaattcggc gaagtctccg
     2941 ttgatgatca actgattggc gaccgcgcca cgcagatcaa aacgctgacc aacggctgca
     3001 tctgctgttc gcgctccaac gagctggaag acgcactact cgacctgctg gataatctcg
     3061 acaagggcaa tattcagttc gaccgtctgg tcattgaatg caccggcatg gccgatcccg
     3121 gcccgattat tcagaccttt ttctcccatg agattttatg ccagcgctac ctgctggacg
     3181 gcgtgattgc gctggttgat gcggtacatg ccgatgagca gatgaaccag ttcaccatcg
     3241 cccagtccca ggttggctac gccgaccgta ttctgctgac gaaaaccgac gtcgcaggcg
     3301 aagcagagaa actgcgtgaa cgcctggcgc gcatcaacgc ccgcgcaccg gtctacaccg
     3361 ttacccacgg cgatatcgac ctgggccttc tgttcaacac caacggtttt atgctggaag
     3421 aaaacgtcgt cagcaccaaa ccgcgtttcc actttatcac ggacaaacaa aacgatattt
     3481 cgtcgattgt ggtggaactg gattacccgg tagatatcag cgaagtttcc cgggtgatgg
     3541 aaaacctgct gctggagtcg gcggataaac tactgcgtta caaagggatg ctatggattg
     3601 acggcgaacc taaccgcctg ctgttccagg gcgtccaacg cctctacagc gccgactggg
     3661 accgcccgtg gggcgatgaa aaaccgcata gcacgatggt gtttatcggg attcagttgc
     3721 cggaggaaga gattcgggca gcgtttgcgg ggttgaggaa gtaattttgg atgatggccg
     3781 ccatgtggcg gcctgaatta ttttttgttc tgatcgcgca gcatcgcttc acgtaaaatt
     3841 gcgttcaggc gagtttgata gcctttacct ggtcgcttca accattccat cacatcagca
     3901 tcaatacgca ccgaagcctg agttttcaat ggccgataaa acttaccgcg ttcggcgtta
     3961 gaccattgct catcgctgga aggtgggata tcactgtaat caatatcttc gtcggattta
     4021 ttcgccagcg ccttcagttc ggcctcatgc tgcacatcga gtgtagagga ggtccctcgt
     4081 ttatgtttaa ccatgctcat agcgattcct ctctttacga tctgcttttc gtgcactgat
     4141 gattcgaata atttcatttc cgctttcgaa acggatggta tgcgcaacca gaataaccac
     4201 gatgccgtaa accaggccga ttgtctgcca gcgatactca ccgttttcta tgcgttcttg
     4261 ctgtgacaaa tgttgtggat catcaaacaa taacaccgca tcttcaaagc ggatgccatg
     4321 tttcacccga ttacttttgg ccttgttttc atcccattca aactccattg gcataattgc
     4381 catccctaat tgtatataca aaaatgtatc tacaattatt ctgcaattat agcgttgatg
     4441 ttggaaatag catcacgttt cgaataatca accatgaaat tgacaatgag taagttggac
     4501 ttgattcatc caatagaatt tctcgcctga catggcacac taaacacctc gctgtcgggt
     4561 aatgactcca acttactgat agtgttttat gttcagataa tgcccgatga ccttgtcatg
     4621 cagctccacc gattttgaga acgacagtga cttccgtccc agccttgcca gatgttgtct
     4681 cagattcaga ttatgtcgct caatgcgctg agtgtaacgc ttgctgataa cgtgcagctt
     4741 tcccttcagg cgtgattcat acagcggcca gccatccgtc atctatacca cgacctcaaa
     4801 ggccgacagc aggctcagaa gacgctccag tgtggccaga gtgcgttcac cgaagacgtg
     4861 gccacaaccg tcctccgtat cctgtcatac gcgtaaaaca gccagcgctg acgtgattta
     4921 gcaccgacgt agccccaatg ttcgtccatt tcagcgcaga
//
LOCUS       DADXDL010000174         4949 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.174, whole genome shotgun sequence.
ACCESSION   DADXDL010000174 DADXDL010000000
VERSION     DADXDL010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4949)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4949)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4949
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.174"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..474
                     /locus_tag="IRB70_004682"
     CDS             <1..474
                     /locus_tag="IRB70_004682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414844.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634497.1"
                     /translation="DLIEILFYLKKKIRIILFIIAICMAMVLLFLYNREIKLEWSGDK
                     RDLPTAEAEISRVHASIIKWYASEYHNGRQVLDEIQTPSAINSELYTKMIYLTRNWSL
                     YPNGDDCVTISSPEIKSKYPAAICLILGFFLSIVISVMFCLVKKMVDEYQQNSGQ"
     gene            complement(717..1412)
                     /locus_tag="IRB70_004683"
     CDS             complement(717..1412)
                     /locus_tag="IRB70_004683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414842.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate utilization protein C"
                     /protein_id="HBC0634498.1"
                     /translation="MDNRSEFLNNVAQALGRPQRLEPQAEDAPLNNYANERLTELNQQ
                     QRCDAFIQFASDVMLTRCELTSEAQAAEAAIRLCKELGDQSIVISGDTRLEELGISER
                     LQQECNVVVWDPAKGIENISQAEQAKVGVVYAEYGLTESGGVVLFSAAGRGRSLSLLP
                     ESSLFILRKSTILPRVAQLAEKLHQKAQAGERMPSCINIISGPSSTADIELIKVVGVH
                     GPVKAVYLIIEDC"
     gene            complement(1405..2832)
                     /locus_tag="IRB70_004684"
     CDS             complement(1405..2832)
                     /locus_tag="IRB70_004684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster-binding protein"
                     /protein_id="HBC0634499.1"
                     /translation="MSIKTSNTDFKTRIRQQIEDPIMRKAVANAQQRIGANRQKMVDE
                     LGHWEEWRDRAAQIRDHVLSNLDAYLYQLSEKVTQNGGHVYFAKTKEDATRYILQVAQ
                     RKNARKVVKSKSMVTEEIGVNHVLQDAGIQVIETDLGEYILQLDQDPPSHVVVPAIHK
                     DRHQIRRVLHERLGYEGPETPEAMTLFIRQKIREDFLSAEIGITGCNFAVAETGSVCL
                     VTNEGNARMCTTLPKTHIAVMGMERIAPTFAEVDVLITMLARSAVGARLTGYNTWLTG
                     PREAGHVDGPEEFHLVIVDNGRSEVLASEFRDVLRCIRCGACMNTCPAYRHIGGHGYG
                     SIYPGPIGAVISPLLGGYKDFKDLPYACSLCTACDNVCPVRIPLSKLILRHRRVMAEK
                     GITAKAEQRAIKMFAYANSHPGLWKVGMMAGAHAASWFINGGKTPLKFGAISDWMEAR
                     DLPEADGESFRSWFKKHQAQEKKNG"
     gene            complement(2843..3562)
                     /locus_tag="IRB70_004685"
     CDS             complement(2843..3562)
                     /locus_tag="IRB70_004685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(Fe-S)-binding protein"
                     /protein_id="HBC0634500.1"
                     /translation="MNVNFFVTCIGDALKSRMARDSVLLLEKLGCRVNFPEKQGCCGQ
                     PAINSGYIKEAIPGMKNLIAALEDNDAPIISPAGSCTYAVKSYPTYLADEPEWASRAE
                     KVAARMQDLTSFIVNTLGVVDVGASLQGRAVYHPSCSLARKLGVKDEPLTLLKNVRGL
                     ELLTFAEQDTCCGFGGTFSVKMAEISGEMVKEKVVHLMEVRPEYLIGADVSCLLNISG
                     RLQREGQKVKVMHIAEVLMSR"
     gene            complement(4088..4942)
                     /gene="rclR"
                     /locus_tag="IRB70_004686"
     CDS             complement(4088..4942)
                     /gene="rclR"
                     /locus_tag="IRB70_004686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator RclR"
                     /protein_id="HBC0634501.1"
                     /translation="MDALSRLLMLNAPQGTIDKNCVLGSDWQLPHGAGELSVIRWHAL
                     TQGAAKLEMPTGEIFTLRPGNVVLLPQNSAHRLSHVDNESTCIVCGTLRLQHSARYFL
                     TSLPETLFVAPVNHSVEYNWLREAIPFLQQESRSAMPGVDALCSQICATFFTLAVREW
                     IAQVNTEKNILSLLLHPRLGAVIQQMLEMPGHAWTVESLASIAHMSRASFAQLFRDVS
                     GTTPLAVLTKLRLQIAAQMFSRETLPVVVIAESVGYASESSFHKAFVREFGCTPGEYR
                     ERVRQLAP"
BASE COUNT         1299 a         1284 c         1063 g         1303 t
ORIGIN      
        1 gatctgattg agattttatt ttatctgaag aaaaagattc gtattatcct ttttattata
       61 gctatctgta tggcaatggt gctgttgttt ctgtataaca gagaaataaa gctggaatgg
      121 tcaggagata agagagattt accaactgct gaagcggaaa tatctcgcgt gcatgcgtct
      181 attatcaaat ggtatgcgtc agaataccat aacggcaggc aagttctcga tgagatacaa
      241 acaccttcag caattaacag tgagctttat acaaaaatga tatacctgac caggaactgg
      301 tcattgtatc cgaacggtga tgactgtgta accataagct caccggaaat aaaaagtaaa
      361 tatcctgctg ccatttgcct gattctggga ttttttctaa gcattgtgat ttctgtaatg
      421 ttttgccttg tcaaaaaaat ggtagatgaa taccaacaaa actctgggca gtaataaaca
      481 gcattctgat agagagtgcc tgtataaagc tgaagtgaca atgaccggga agggaacccg
      541 ttttcaggaa tggatgcctg tctttttcac tttaaatatc ctggcattag taatgccagg
      601 atatttacag aagagcagca taaccatgac ggaacggggt taagtcaggt tgtcctaaac
      661 gctattttca acctcgtatg ccttcttcag gtttatgtcc agacttcata tctctctcaa
      721 caatcctcaa taatcagata caccgctttc accgggccat gaactccgac gactttgata
      781 agctcaatat ccgccgttga actggggccg ctaatgatgt taatgcagga aggcattcgt
      841 tcaccggcct gcgctttctg atgcaatttt tctgcgagtt gcgctacacg cggcaggata
      901 gtgcttttac gcaggataaa aagagaagat tccgggagca ggctcaatga acgcccgcgc
      961 ccggcggcgg aaaaaagaac cacgcctccc gattcggtta aaccatattc agcatacact
     1021 acgccaactt tagcctgctc tgcttgtgat atgttctcaa tacctttcgc cggatcccaa
     1081 acaacgacat tgcattcctg ctgcaaacgt tcgctaatcc ccaattcctc cagcctcgtg
     1141 tcaccgctaa tcacgatcga ctgatctccc agctctttac acagacgtat tgcagcttct
     1201 gcggcctgcg cctcgctggt cagttcacag cgcgtcaaca taacatcgct ggcaaactgg
     1261 ataaacgcgt cacagcgctg ctgttggtta agttcggtaa gccgctcgtt agcatagttg
     1321 tttagcggcg catcttctgc ttgcggttca agtcgctgcg ggcgacccag tgcctgagca
     1381 acgttattca aaaattcgct ccgattatcc attctttttc tcctgcgcct gatgtttctt
     1441 aaaccaacta cggaaactct ctccgtcagc ttcaggaaga tcgcgtgctt ccatccagtc
     1501 gctaatcgcg ccaaatttga gtggtgtttt gccgccattg ataaaccagc ttgccgcatg
     1561 agcgccggcc atcatcccga ctttccacaa tcctggatga ctattggcat aagcgaacat
     1621 ttttatcgcc cgttgctctg cttttgcggt gatccctttt tcagccatca cccgacgatg
     1681 acgcaaaatc agttttgaca gcggaatacg caccggacac acgttgtcac aagcagtgca
     1741 taaagagcag gcgtagggta aatctttaaa atctttatag ccgccaagta gcggagaaat
     1801 caccgcacca attggccctg gataaataga gccatatcca tgaccgccaa tatggcgata
     1861 tgccggacaa gtattcatac aagccccgca gcgaatacag cgcagcacat cccgaaattc
     1921 agaggccagc acctcagaac gcccgttatc gacaataacc agatgaaact cttcaggacc
     1981 atcaacgtgc cccgcttcgc gcggtcctgt cagccaggtg ttgtatcccg tcaaacgtgc
     2041 accaacggca ctgcgcgcca gcatggtgat caatacatct acctcggcaa acgtgggggc
     2101 aatacgctcc attcccatca ctgcaatatg cgttttaggc agcgtggtac acattcgcgc
     2161 attaccttca ttggtcacca ggcataccga accggtctct gccaccgcga aattacagcc
     2221 ggtaatacct atttcagcac tgaggaaatc ttcgcggatt ttttgccgaa tgaataaggt
     2281 catcgcttca ggcgtttccg gcccttcata gcccagacgt tcgtgtagca ctcgacggat
     2341 ctgatggcga tctttatgaa ttgccgggac cacaacatga gagggcggat cttgatccag
     2401 ctggagaatg tattcaccca gatcggtttc aatcacctga atgccagcat cctgcaacac
     2461 atgattgaca ccaatctctt cggtcaccat cgatttagat ttcaccacct tccgggcatt
     2521 tttgcgttgg gcaacctgta aaatgtagcg ggtagcgtct tctttggttt ttgcaaaata
     2581 gacgtgaccg ccgttttgcg tcactttttc tgagagctgg tacagataag cgtcgagatt
     2641 actcagaaca tgatcacgta tctgggcggc ccgatcgcgc cattcctccc agtgccccaa
     2701 ttcatcgacc attttttgcc gatttgcccc gatacgctgc tgcgcgtttg ccaccgcttt
     2761 gcgcatgatc ggatcttcaa tttgctgacg gatgcgtgtc ttaaaatctg tattactggt
     2821 tttgatcgac atctttatat cctcagcgac tcatcagcac ttcagcaata tgcatcactt
     2881 tgactttctg cccttcccgt tgtaatcgtc cactgatgtt cagcaggcaa ctcacgtcag
     2941 caccaattaa atactcaggg cggacttcca tcaggtgcac aaccttttct ttcaccatct
     3001 cgccggatat ttcggccatt ttgaccgaga acgtgccgcc aaatccgcag caggtatcct
     3061 gttcagcaaa ggtcaacagc tccagtccac gcacattttt cagcagcgta agtggttcgt
     3121 ccttcacccc cagcttacgg gccaggctac aagatgggtg atacaccgct ctcccttgca
     3181 aactggcacc tacatcgact acccctaatg tattaacaat aaaagaggtg agatcctgca
     3241 tacgcgcggc aaccttttcg gcacgtgatg cccattcagg ttcatccgcc agatacgtcg
     3301 ggtaactttt tacggcatag gtgcaagagc cagccggtga aataatggga gcgtcgttat
     3361 cctccagtgc ggcgatcaga tttttcatcc ctggaatcgc ttctttgata taaccactat
     3421 tgatcgcagg ctgaccgcag catccctgtt tctccgggaa atttacgcga cagccgagtt
     3481 tttccagtag cagcacggag tctcgtgcca ttcttgattt cagggcgtca ccaatacagg
     3541 tgacaaagaa attgacattc acaactaata ctccattact tcatgcccat ttatgcccga
     3601 tggttccccc cttccggggg atcaatcatc aataaatatg gcgttctttt ttaattggct
     3661 agcaacatac cacccctcat ttgtatgaca aatgataatc tttcatctaa acttcaaatg
     3721 caataactaa ttttatttct ttcggcatcg ctcacatttt atagggaaat cgacgatcat
     3781 ttttggcata agaaatccat ttaaaaaggc tacacccctt atacctattc agagctactt
     3841 attcaggggt tattgagata tacactgatg gtgtacaaaa aaatcaccga caataatcac
     3901 gcatcaagta atagtcggga ttttatttaa ttgaagcaat ttagtttgca tttttattta
     3961 aaaactgagc tagagtccat caaaaaaata tataaagccc aaaaccaccg ttggaaatag
     4021 aaatagttga aaggctcaca actcccggaa tgcggattat ctttgccctg atttctggcg
     4081 gttttattca gggtgcaagc tgtctgaccc tttcccgata ttctcccggg gtacaaccaa
     4141 actcgcgaac aaacgccttg tgaaaagatg attcactggc atagcctact gactcagcga
     4201 tcaccacaac agggagcgtt tcccgggaaa acatctgggc cgctatttgt agacgcaact
     4261 ttgttaatac agccagcggc gtggttccgg aaacatcacg gaaaagctgg gcaaaacttg
     4321 cccgggacat gtgggcgatg ctggccagcg attcgacggt ccaggcgtgt cctggcattt
     4381 ccagcatttg ctgtattacc gcaccaagac gtggatgcag aagcaaactg agaatgtttt
     4441 tctctgtatt aacctgtgca atccactcac gcaccgcgag ggtaaagaat gtagcgcaga
     4501 tctggctaca cagagcatcc actcccggca ttgccgatct ggattcctgt tgtaaaaacg
     4561 ggatcgcctc cctcagccag ttatattcca cgctatggtt cactggtgct acaaacagcg
     4621 tttccggcaa agacgttaaa aaataacgcg ccgaatgttg cagtcgaaga gtgccacaga
     4681 caatacaggt cgattcatta tcgacatgac tcaggcgatg agctgaattt tgtggtagca
     4741 ggaccacatt tcccgggcgt aatgtaaaaa tctctcccgt cggcatttcc agcttcgccg
     4801 ctccttgcgt taacgcatgc caacgaataa ccgacaattc cccggcacca tgtggaagtt
     4861 gccagtcact tcctaacacg caattcttat cgatcgttcc ttgtggagcg ttaagcatca
     4921 acaaacggct aagagcatcc atatcagac
//
LOCUS       DADXDL010000175         4944 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.175, whole genome shotgun sequence.
ACCESSION   DADXDL010000175 DADXDL010000000
VERSION     DADXDL010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4944)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4944)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4944
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.175"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1178
                     /locus_tag="IRB70_004687"
     CDS             <1..1178
                     /locus_tag="IRB70_004687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS1380-like element ISEc9 family transposase"
                     /protein_id="HBC0634502.1"
                     /translation="IFDFIENDLVFDNDSTNKIKMNHIKTMLCGHFIGIDKLERLKLL
                     QNDPLVNEFDISVKEPETVSRFLGNFNFKTTQMFRDINFKVFKKLLTKSKLTSITIDI
                     DSSVINVEGHQEGASKGYNPKKLGNRCYNIQFAFCDELKAYVTGFVRSGNTYTANGAA
                     EMIKEIVANIKSDDLEILFRMDSGYFDEKIIETIESLGCKYLIKAKSYSTLTSQATNS
                     SIVFVKGEEGRETTELYTKLVKWEKDRRFVVSRVLKPEKERAQLSLLEGSEYDYFFFV
                     TNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGHLLLKSFWANEAVFQMMMLSYNLF
                     LLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTARYVIMKLSENYPYKGVYEKCLV"
     gene            1434..2309
                     /locus_tag="IRB70_004688"
     CDS             1434..2309
                     /locus_tag="IRB70_004688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A extended-spectrum beta-lactamase
                     CTX-M-15"
                     /protein_id="HBC0634503.1"
                     /translation="MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQS
                     GGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKK
                     SDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGD
                     ETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNT
                     TGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESR
                     RDVLASAAKIVTDGL"
     gene            complement(2356..2688)
                     /locus_tag="IRB70_004689"
     CDS             complement(2356..2688)
                     /locus_tag="IRB70_004689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001393253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WbuC family cupin fold metalloprotein"
                     /protein_id="HBC0634504.1"
                     /translation="MRPHRHPHTFELLLPLRGRFVVLNFDDRGTVTHRAILGETCTVL
                     EMAAGTWHAVLSLDTGGIIFEVKHGGYQPVAADDYAHWAPAEGEPGTTELMAWYAQAQ
                     VGDSTFAV"
     gene            2702..4944
                     /locus_tag="IRB70_004690"
                     /pseudo
     CDS             2702..4944
                     /locus_tag="IRB70_004690"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495017.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element Tn3 family transposase"
BASE COUNT         1362 a         1125 c         1229 g         1228 t
ORIGIN      
        1 ggatttttga ttttattgaa aatgacctcg tatttgataa tgactcaaca aataaaatca
       61 agatgaatca tataaagacc atgctctgcg gtcacttcat tggcattgat aagttagaac
      121 gtctaaagct acttcaaaat gatcccctcg tcaacgagtt tgatatttcc gtaaaagaac
      181 ctgaaacagt gtcacggttt ctaggaaact tcaacttcaa gacaacccaa atgtttagag
      241 acattaattt taaagtcttt aaaaaactgc tcactaaaag taaattgaca tccattacga
      301 ttgatattga tagtagtgta attaacgtag aaggtcatca agaaggtgcg tcaaaaggat
      361 ataatcctaa gaaactggga aaccgatgct acaatatcca atttgcattt tgcgacgaat
      421 taaaagcata tgttaccgga tttgtaagaa gtggcaatac ttacactgca aacggtgctg
      481 cggaaatgat caaagaaatt gttgctaaca tcaaatcaga cgatttagaa attttatttc
      541 gaatggatag tggctacttt gatgaaaaaa ttatcgaaac gatagaatct cttggatgca
      601 aatatttaat taaagccaaa agttattcta cactcacctc acaagcaacg aattcatcaa
      661 ttgtattcgt taaaggagaa gaaggtagag aaactacaga actgtataca aaattagtta
      721 aatgggaaaa agacagaaga tttgtcgtat ctcgcgtact gaaaccagaa aaagaaagag
      781 cacaattatc acttttagaa ggttccgaat acgactactt tttctttgta acaaatacta
      841 ccttgctttc tgaaaaagta gttatatact atgaaaagcg tggtaatgct gaaaactata
      901 tcaaagaagc caaatacgac atggcggtgg gtcatctctt gctaaagtca ttttgggcga
      961 atgaagccgt gtttcaaatg atgatgcttt catataacct atttttgttg ttcaagtttg
     1021 attccttgga ctcttcagaa tacagacagc aaataaagac ctttcgtttg aagtatgtat
     1081 ttcttgcagc aaaaataatc aaaaccgcaa gatatgtaat catgaagttg tcggaaaact
     1141 atccgtacaa gggagtgtat gaaaaatgtc tggtataata agaatatcat caataaaatt
     1201 gagtgttgct ctgtggataa cttgcagagt ttattaagta tcattgcagc aaagatgaaa
     1261 tcaatgattt atcaaaaatg attgaaaggt ggttgtaaat aatgttacaa tgtgtgagaa
     1321 gcagtctaaa ttcttcgtga aatagtgatt tttgaagcta ataaaaaaca cacgtggaat
     1381 ttagggacta ttcatgttgt tgttatttcg tatcttccag aataaggaat cccatggtta
     1441 aaaaatcact gcgccagttc acgctgatgg cgacggcaac cgtcacgctg ttgttaggaa
     1501 gtgtgccgct gtatgcgcaa acggcggacg tacagcaaaa acttgccgaa ttagagcggc
     1561 agtcgggagg cagactgggt gtggcattga ttaacacagc agataattcg caaatacttt
     1621 atcgtgctga tgagcgcttt gcgatgtgca gcaccagtaa agtgatggcc gcggccgcgg
     1681 tgctgaagaa aagtgaaagc gaaccgaatc tgttaaatca gcgagttgag atcaaaaaat
     1741 ctgaccttgt taactataat ccgattgcgg aaaagcacgt caatgggacg atgtcactgg
     1801 ctgagcttag cgcggccgcg ctacagtaca gcgataacgt ggcgatgaat aagctgattg
     1861 ctcacgttgg cggcccggct agcgtcaccg cgttcgcccg acagctggga gacgaaacgt
     1921 tccgtctcga ccgtaccgag ccgacgttaa acaccgccat tccgggcgat ccgcgtgata
     1981 ccacttcacc tcgggcaatg gcgcaaactc tgcggaatct gacgctgggt aaagcattgg
     2041 gcgacagcca acgggcgcag ctggtgacat ggatgaaagg caataccacc ggtgcagcga
     2101 gcattcaggc tggactgcct gcttcctggg ttgtggggga taaaaccggc agcggtggct
     2161 atggcaccac caacgatatc gcggtgatct ggccaaaaga tcgtgcgccg ctgattctgg
     2221 tcacttactt cacccagcct caacctaagg cagaaagccg tcgcgatgta ttagcgtcgg
     2281 cggctaaaat cgtcaccgac ggtttgtaat agcggaaacg gaatggggaa actcattccg
     2341 tttttgttta tcgccttaga cggcaaaagt gctgtcgccc acctgcgctt gcgcatacca
     2401 ggccataagc tccgtggttc ctggttctcc ttccgctgga gcccagtgcg catagtcatc
     2461 ggcagccacg ggttgatagc caccgtgttt tacttcaaaa attatgccac cggtatccag
     2521 cgacagcacg gcatgccagg ttcctgcggc catctccagc accgtacagg tttcccccaa
     2581 tatcgcccga tgggtgacgg taccccgatc gtcaaaattc agcaccacga aacgacccct
     2641 taatggcaac agtagctcga aggtgtgagg gtgtcggtgc gggcgcacgt aggtcccagg
     2701 tcatattcct tccggcgtcc ggcattttac cgccagacag ctcgggattc gtgatatcac
     2761 cgttcttgca gaatacggtc agagggaaaa tacccgccgt gagcatgcag cgctgatacg
     2821 tcagcactat cagtatcgtg aatttgcctg gccctggaca tttcgcctta cccgtctttt
     2881 atatacccgg agctggataa gcaacgaacg tcctggcctg cttttcgatc tggcgacagg
     2941 gtggcttatg caacatcgta ttattctccc cggagccact acgctgaccc ggttgatttc
     3001 agaggtaagg gaaaaggcga cgttgcgcct gtggaacaaa ctggcactga taccgtcagc
     3061 cgaacagcgt tcacagctgg agatgctgct ggggccaact gattgcagcc gcctgtcttt
     3121 actggaatca ctgaaaaagg gccctgtgac catcagtggt ccggcgttta atgaagcaat
     3181 tgaacgctgg aaaactctga acgattttgg cctgcatgct gaaaacctga gtacactccc
     3241 ggctgtgcgc ctgaaaaatc tcgcacgtta tgctggtatg acttcggtgt tcaatattgc
     3301 caggatgtca ccgcagaaaa ggatggcggt tctggttgcc tttgtccttg catgggaaac
     3361 gctggcgctg gatgatgcat tggacgttct ggacgccatg ctggccgtta tcatccgtga
     3421 cgccagaaag attgggcaga aaaaacggct ccgctcgctg aaggatctgg ataaatctgc
     3481 attggcgctc gccagcgcat gttcgtacct gctgaaagaa gaaacaccgg acgaatcgat
     3541 tcgtgctgag gtgttcagct acatcccaag gcaaaagctg gctgaaatca tcacgcttgt
     3601 ccgtgaaatt gcccggccct cagacgataa ttttcatgaa gaaatggtgg agcagtacgg
     3661 gcgcgttcgt cgtttcctgc cccatctgct gaataccgtt aaattttcat ccgcacctgc
     3721 cggggttacc actctgaatg cctgtgacta cctcagccgg gagttcagct cacggcggca
     3781 gttttttgac gacgcaccaa cggaaattat cagtcggtca tggaaacggc tggtgattaa
     3841 caaggaaaaa catatcaccc gcaggggata cacgctctgc tttctcagta aactgcagga
     3901 tagtctgagg cggagggatg tctacgttac cggcagtaac cggtggggag atcctcgtgc
     3961 aagattacta cagggtgctg actggcaggc aaaccggatt aaggtttatc gttctttggg
     4021 gcacccgaca gacccgcagg aagcaataaa atctctgggt catcagcttg atagtcgtta
     4081 cagacaggtt gctgcacgtc tttgcgaaaa tgaggctgtc gaactcgatg tttctggccc
     4141 gaagccccgg ttgacaattt ctcccctcgc cagtcttgat gagccggaca gtctgaaacg
     4201 actgagcaaa atgatcagtg atctactccc tccggtggat ttaacggagt tgctgctcga
     4261 aattaacgcc cataccggat ttgctgatga gtttttccat gctagtgaag ccagtgccag
     4321 agttgatgat ctgcccgtca gcatcagcgc cgtgctgatg gctgaagcct gcaatatcgg
     4381 tctggaacca ctgatcagat caaatgttcc tgcactgacc cgacaccggc tgaactggac
     4441 aaaagcgaac tatctgcggg ctgaaactat caccagcgct aatgccagac tggttgattt
     4501 tcaggcaacg ctgccactgg cacagatatg gggtggagga gaagtggcat ctgcagatgg
     4561 aatgcgcttt gttacgccag tcagaacaat caatgccgga ccgaaccgca aatactttgg
     4621 taataacaga gggatcacct ggtacaactt tgtgtccgat cagtattccg gctttcatgg
     4681 catcgttata ccggggacgc tgagggactc tatctttgtg ctggaaggtc ttctggaaca
     4741 ggagaccggg ctgaatccaa ccgaaattat gaccgataca gcaggtgcca gcgaacttgt
     4801 ctttggcctt ttctggctgc tgggatacca gttttctcca cgcctggctg atgccggtgc
     4861 ttcggttttc tggcgaatgg accatgatgc cgactatggc gtgctgaatg atattgccag
     4921 agggcaatca gatccccgaa aaat
//
LOCUS       DADXDL010000176         4735 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.176, whole genome shotgun sequence.
ACCESSION   DADXDL010000176 DADXDL010000000
VERSION     DADXDL010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4735
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.176"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1187..1903
                     /gene="nanC"
                     /locus_tag="IRB70_004691"
     CDS             1187..1903
                     /gene="nanC"
                     /locus_tag="IRB70_004691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313297.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminic acid outer membrane channel
                     NanC"
                     /protein_id="HBC0634505.1"
                     /translation="MKKAKILSGVLLLCFSSPLISQAATLDVRGGYRSGSHAYETRLK
                     VSEGWQNGWWASMESNTWNTIHDNKKENAALNDVQVEVNYAIKLDDQWTVRPGMLTHF
                     SSNGTRYGPYVKLSWDATKDLNFGIRYRYDWKAYRQQDLSGDMSRDNVHRWDGYVTYH
                     INSDFTFAWQTTLYSKQNDYRYANHKKWATENAFVLQYHMTPDITPYIEYDYLDRQGV
                     YNGRDNLSENSYRIGVSFKL"
     gene            1923..3029
                     /gene="nanM"
                     /locus_tag="IRB70_004692"
     CDS             1923..3029
                     /gene="nanM"
                     /locus_tag="IRB70_004692"
                     /EC_number="5.1.3.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418730.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate epimerase"
                     /protein_id="HBC0634506.1"
                     /translation="MNKTITALAIIMASFAANASVLPETPVPFKSGTGAIDNDTVYIG
                     LGSAGTAWYKLDTQAKDKKWTALAAFPGGPRDQATSAFIDGNLYVFGGIGKNSEGLTQ
                     VFNDVHKYNPKTNSWVKLMSHAPMGMAGHVTFVHNGKAYVTGGVNQNIFNGYFEDLNE
                     AGKDSTTIDKINAHYFDKKAEDYFFNKFLLSFDPSTQQWSYAGESPWYGTAGAAVVNK
                     GDKTWLINGEAKPGLRTDAVFELDFTGNNLKWNKLAPVASPDGVAGGFAGMSNDSLIF
                     AGGAGFKGSRENYQNGKNYAHEGLKKSYSADIHLWHNGKWDKSGELSQGRAYGVSLPW
                     NNSLLIIGGETAGGKAVTDSVLISVKDNKVTVQN"
     gene            3094..4074
                     /locus_tag="IRB70_004693"
     CDS             3094..4074
                     /locus_tag="IRB70_004693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sialate O-acetylesterase"
                     /protein_id="HBC0634507.1"
                     /translation="MNAIISPDYYYVLTVAGQSNAMAYGEGLPLPDKEDAPHPRIKQL
                     ARFAHTHPGGPSCHFNDIIPLTHCPHDVQDMQDYHHPLATNHQTQYGTVGQALHIARK
                     LLPFIPDNAGVLIVPCCRGGSAFTAGSEGTYSERHGASHDACRWGTDTPLYQDLVSRT
                     RAALAKNPQNKFLGVCWMQGEFDLMTSDYASHPQHFNHMVDAFRRDLKQYHSQLNKIT
                     DAPWFCGDTTWYWKENFPHAYEAIYGNYQNNVLANIIFVDFQQQGARGLTNAPDEDPD
                     DLSTGYYGSAYRSPENWTTALRSSHFSAAARRGIISDRFVEAILQFWRER"
     gene            complement(4082..4204)
                     /locus_tag="IRB70_004694"
     CDS             complement(4082..4204)
                     /locus_tag="IRB70_004694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012139841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBC0634508.1"
                     /translation="MISYVFLLPVCPNCHAMLHRRKPPFTPEELKALMDANKSN"
     gene            4300..4722
                     /locus_tag="IRB70_004695"
     CDS             4300..4722
                     /locus_tag="IRB70_004695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006174194.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBC0634509.1"
                     /translation="MADEPFFALQQIRKQRDPLFRKHVLRAYNYQCAICSFNICYGNS
                     TVSLEATHIKWKQHGGPCEIPNGLALCAIHHKAFDKGTIGLDENMRVLVLDAVNGGEI
                     IERSFWDFDGKIIALPQVRKNYPFEGVVEWHRKEFFRG"
BASE COUNT         1425 a          979 c         1054 g         1277 t
ORIGIN      
        1 taatcttatc tatatatcat gtgatatgtt ctgtaacaag taaaatcaac ataaaaaatt
       61 cagcaaaatt taatattcgc tcaactagcc gtctcacata tgacattatt agtcaactcc
      121 atttgccaca aaatggctat ttcatggaac gcagtaattt cttagtggct attatcatgc
      181 taattcttag gtccctagcg attattcctg gctggttcgt cagtttagac catgagattg
      241 ttacattcct ttttatcatg gagatatggg ggaaagcagg aaacgatttt ttcatctgca
      301 tccgttggta aatatggctt tggtcactac gacttaaacc ttcctcaatc acagctgttc
      361 gccgggcgat acggcaaaca aactaagtga ggcatcaccc tgaaaacacc aacatcaaca
      421 agcctctcca gatcggcttc aggagtgacc agttacaagc cacaaaccag gaaacatatt
      481 tcatgatgag aattatgcta agcctgatgg cgggtaaaca cttattttca ccaagctcac
      541 tgagttagct tacaaagctt cccttattta gactctaaat aaatttttta taaaacagat
      601 atttaaaaga atatctttag tttttgaaga ccaccgcaag tgttcgtctg gcttcacatg
      661 gcatcttcct cttagaaaaa gatcgacata ttttgtgaca cgaattgcaa atctggtttt
      721 gttgtatgga ttgcgtgatt tttgatctgg tataacaggt ataaaggtgc accgcgatag
      781 acaatgagac agggcatctt gcaatctatg gcaaacatca cttcagttct ttctcatcgg
      841 gtgatgaaaa cgcacttcag tctgaaagga atatgaaaat gagatcaaca aacactctat
      901 tttatgactc tgggtaaaat ggattgagta agtgatatag cttacgaaca ttcaaatcaa
      961 ttaaacatca gaagagattt tatactcagg tatttaatct ggctctctgt ttatttaaat
     1021 aatgtgaaaa gagaattttc acaggagacc ttatacaaaa aatataaaat aagctaccca
     1081 ttgccaaaga cactataagc ctggcaaaaa atattacaca acataaatgc taattgttta
     1141 tgcgggcttt gtattgcttt ctgtatccta caaatgagtg aaatttatga aaaaggctaa
     1201 aatactttct ggcgtattat tactgtgctt ttcgtcacca ttaatttctc aggctgcgac
     1261 actggacgta cgtggtggat atcgtagcgg aagccatgcc tatgagactc ggctcaaagt
     1321 cagtgaggga tggcaaaatg gatggtgggc aagcatggaa agtaatacct ggaataccat
     1381 tcatgataat aaaaaggaaa atgccgcact caatgatgtt caggttgaag ttaattacgc
     1441 gattaaactt gatgatcaat ggacggtgcg cccgggaatg ttaacgcatt ttagcagcaa
     1501 cggcacccgc tacggaccct acgtaaaact gtcctgggac gcgacaaaag atcttaattt
     1561 tggcattcgc tatcgttacg actggaaagc ttaccgacaa caagacttat ccggtgatat
     1621 gtctcgtgat aacgttcatc gttgggatgg atatgtcact taccatatta atagtgattt
     1681 caccttcgca tggcaaacga cgctatacag caaacagaac gattatcgct atgcaaacca
     1741 taagaaatgg gcgacggaaa atgcatttgt tctacaatac catatgacgc ccgatattac
     1801 gccatacata gaatatgact accttgaccg tcagggtgtt tacaacggca gagataattt
     1861 atcggaaaac agttatcgca ttggtgtatc atttaaactg tagtagacag gagacagtca
     1921 caatgaataa aacaataacg gcgcttgcta tcataatggc ttcatttgcc gcaaacgcgt
     1981 ctgtattacc ggaaactcct gtgccattta aaagtggtac cggagcaatt gataacgaca
     2041 ctgtctacat tggtttaggt agcgcaggta cagcatggta caagctggat acacaggcca
     2101 aagataaaaa atggacagcg ttagctgcat tccctggtgg accgagagat caagcaacct
     2161 ctgcatttat tgatggtaat ctgtatgtgt ttggcggcat tggcaaaaac agcgagggct
     2221 tgactcaggt atttaatgac gtacacaaat acaaccccaa aaccaatagc tgggttaaat
     2281 tgatgtcgca cgcgccgatg ggcatggcgg gccatgtgac ttttgtacac aacggcaagg
     2341 cttatgttac tggcggtgtt aaccagaata tcttcaatgg ctattttgaa gatctcaacg
     2401 aagctggaaa agattcaacc actatagata aaatcaacgc ccactatttt gacaaaaaag
     2461 cagaagatta tttcttcaat aagtttctgt tgtcttttga tccctctaca cagcaatgga
     2521 gttacgctgg cgaatctccc tggtacggaa cggctggtgc ggcggttgtg aataaaggtg
     2581 ataaaacctg gcttattaat ggcgaagcca aaccaggatt gcgaacggat gccgtatttg
     2641 aacttgattt caccggtaat aatttaaaat ggaataagct tgctcccgtc gcatcaccag
     2701 atggcgtcgc tggcggtttt gcaggcatga gcaatgactc acttatattt gccggagggg
     2761 ccggattcaa aggttcacga gaaaattacc agaacggtaa gaactatgcg catgaaggcc
     2821 tgaaaaaatc atatagcgct gatattcatc tttggcataa cgggaaatgg gataaatcgg
     2881 gcgaattatc gcaaggtcgg gcctacggag tatcattgcc ctggaataat agtttattaa
     2941 ttattggcgg tgaaactgca ggcggcaaag cggtgacgga ttcagtttta atttctgtga
     3001 aggataataa agtcacagta caaaactaac gcttcagggc cccggtaaag gggccttgct
     3061 atcaatttgt catttgtatt acgcgaaaat tatatgaacg caataatatc gcccgattat
     3121 tactatgttc ttaccgttgc tggtcagtct aatgccatgg cgtatggcga aggactacca
     3181 ttaccggaca aggaagatgc gcctcatccc agaattaaac aattagcgag atttgcgcat
     3241 acacatcccg gaggcccgtc atgtcacttt aacgacatta ttccactgac tcactgccca
     3301 cacgatgttc aggatatgca ggattatcac catcctctgg caacgaatca tcaaacacag
     3361 tacggcaccg ttggccaggc actacatata gcacggaaat tactgccctt tattcctgat
     3421 aatgcagggg ttctcatcgt tccgtgttgc cgtggcggat cggcttttac cgcgggcagc
     3481 gaagggacat attcagaacg gcacggagcc agccatgatg cttgtcgttg gggaacggat
     3541 actccgctat accaggattt agtcagcaga acgcgagccg cactggcaaa aaatccgcag
     3601 aacaaattcc tcggcgtatg ctggatgcaa ggcgaatttg acttaatgac cagtgactac
     3661 gcgtcacacc ctcaacactt taatcatatg gttgacgcct ttcgtaggga tctaaaacaa
     3721 taccattctc agcttaataa aattactgac gcgccgtggt tttgcggcga taccacctgg
     3781 tactggaaag aaaatttccc tcatgcgtat gaagctattt atggcaatta tcaaaataat
     3841 gttctagcca atattatttt cgtcgacttc cagcaacaag gtgcaagagg actgacgaac
     3901 gcgcctgatg aagatccgga cgatttaagc acgggatatt acggttcagc gtaccggtca
     3961 ccggagaact ggacgacggc actgcgaagc agtcatttca gcgcggcagc ccgtcgaggg
     4021 attatttctg acaggtttgt agaagcaatt ttgcagtttt ggcgcgaaag gtgagcgttc
     4081 attaatttga tttattcgca tccatcagcg cttttaactc ctccggcgta aacggtggtt
     4141 tgcgtcggtg caacatcgca tggcaattag ggcacacagg aagtaaaaaa acatatgaga
     4201 tcaaggtaat atatcttcgc ttgcaggctt gaaccgcaga aaatttgcga gcatgatcgc
     4261 aattatttca ctgccaggga tatcaatggc ttccagtaaa tcgctgacga gccttttttt
     4321 gctctccagc aaatccgtaa gcagcgtgac ccattatttc gcaaacatgt attacgcgct
     4381 tataactacc agtgcgcaat atgtagcttt aatatttgtt acggcaactc caccgtctca
     4441 ctggaagcga cacatataaa atggaaacaa catggtggcc cttgtgaaat tcccaatggc
     4501 ctggcgcttt gcgcgataca tcataaagcc tttgataaag gaacgattgg cctggatgaa
     4561 aatatgcggg tactggtatt ggatgcggta aacggcggag agatcattga gaggtcattc
     4621 tgggattttg acggaaaaat tattgcgttg ccacaggtgc gtaaaaatta cccttttgag
     4681 ggggttgtag agtggcatcg gaaagagttt tttagggggt gaggtaacca ttata
//
LOCUS       DADXDL010000177         4732 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.177, whole genome shotgun sequence.
ACCESSION   DADXDL010000177 DADXDL010000000
VERSION     DADXDL010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4732)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4732)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4732
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.177"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            352..552
                     /locus_tag="IRB70_004696"
     CDS             352..552
                     /locus_tag="IRB70_004696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000159335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634510.1"
                     /translation="MTKEEFVSYIFDKTVEMYAATYGSCNPLNKPEGKDDFDKIYRFL
                     EDRYIKRLEDAGIKSPVKSPLS"
     gene            complement(521..898)
                     /locus_tag="IRB70_004697"
     CDS             complement(521..898)
                     /locus_tag="IRB70_004697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001241301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634511.1"
                     /translation="MRLTMEFKDLPSDVQKTAAHTLHSVLREIGKDIASEPAKDLARK
                     IKTAFVELYNVGTDSETVETKTVSSPIFSLEPGVLSGEICTEISSELLPVIREAICRR
                     GLDGSYDHDVLQVLRTMVTSLGI"
     gene            complement(898..1050)
                     /locus_tag="IRB70_004698"
     CDS             complement(898..1050)
                     /locus_tag="IRB70_004698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1391 family protein"
                     /protein_id="HBC0634512.1"
                     /translation="MDTIDLGNSESLVCGVFPNQDGTFTAMTYTKSKTFKTESGARCW
                     LARNTD"
     gene            complement(1243..1650)
                     /locus_tag="IRB70_004699"
     CDS             complement(1243..1650)
                     /locus_tag="IRB70_004699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001003380.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0634513.1"
                     /translation="MNEKTLGQRIRERRKQVGLSQNGLSKAAGVSGSSISLWESDHTA
                     PRGQNLHRLAEVLQCSPTWILFGDEDKTPAPPVSLDSALDLSEDELEMLRLYRALPKS
                     EQQAQLSELRARVENFNRLFTELLEARKRNKHQ"
     gene            1728..1955
                     /locus_tag="IRB70_004700"
     CDS             1728..1955
                     /locus_tag="IRB70_004700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000920568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBC0634514.1"
                     /translation="MFKSDVINFYGTKAKVAKAAGVDPSAVSQWQELVPEGRAMRLQE
                     ASGGELLYDPKVYDEYRKTKRAGRLNNENHS"
     gene            1939..2460
                     /locus_tag="IRB70_004701"
     CDS             1939..2460
                     /locus_tag="IRB70_004701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001578395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634515.1"
                     /translation="MKITPEQAREALDAWICRPGMTQKQATILITEAFWALKERPNID
                     VQRVTDEGGAVDQRALGVNRVKIFERWKAIDTRDKREKFTALVPAIMEAIRINDFRLY
                     REISDGKSITYMIAGLNKEYGDVVESGLLFADPAVVDRETDELIEKAIAFKLAYRQQY
                     QQKAGWNYEPSFC"
     gene            2441..3406
                     /locus_tag="IRB70_004702"
     CDS             2441..3406
                     /locus_tag="IRB70_004702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001373617.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634516.1"
                     /translation="MSLLFAERPLVINTQLAMKIGLNEAIVLQQLHYWLRDTNSGMEC
                     DGVRWIYNTTEQWLEQFPFWSESTLKRAFASLKTLGLLRCEKLNKSKRDMTNFYTINY
                     GSELLDGGKLSESIGLKCAAPSGQNDTMEEVKMKRSIGSKRPNVIGSKWPDDLTENTT
                     EITTENKNTFRPEASQPDPQTAEQDFLTRNPDAVVFSAKKRQWGSREDLACAQWIWGR
                     IVNLYEQAASDDGEIMRPKEPNWTAWANDVRTMRMLDGRSHRQICEMFGRVQRDQFWV
                     KNIMSPSKLREKWDELVIRLGRSPVQRCMNHISEPDTEIPPGFRG"
     gene            3447..3848
                     /locus_tag="IRB70_004703"
     CDS             3447..3848
                     /locus_tag="IRB70_004703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF977 family protein"
                     /protein_id="HBC0634517.1"
                     /translation="MAKVFTQEEREKIKGQVVELVRQSGRETLRQLEAKTGATRYLMS
                     VLARELVASGDVYNSGYGLFPSEQARKDWQNARKKLSRAKVKKTAVVDPDLIWSLPDG
                     EIRRYDSRLNIICRECRMSEVMQRILAFYQG"
     gene            4048..>4732
                     /locus_tag="IRB70_004704"
     CDS             4048..>4732
                     /locus_tag="IRB70_004704"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634518.1"
                     /translation="MSRMIIDTNILYSLVGLSTNQKIINSPIDQFKLSITTPSLIEVI
                     SKYCNDLGAVKKCISPIINGNIELISIGHTPISNEFLYRLHFSDKIDEVKDIIDNVRA
                     LKISREAEFYRFILILVVSGLFEVIREDGYKFDNDVQNQSQLSLVQTLLESNMELILD
                     FFKDELRNGYINGNEQQSALKAFETMLIGLLHAFHVNYHMIKTDTVNISGSQDRLKNL
                     YDSIKNDNFD"
BASE COUNT         1374 a          959 c         1148 g         1251 t
ORIGIN      
        1 catcacaaaa ttcactttaa aaagggcggc agagcagtca cggagtaaaa ctgataccgc
       61 caaacgtcac cagaaaattg ataacagagg gcgttgcagc ggggttgtca cttaagcgta
      121 tggtcaacct gacaactcgg tgtcctcaac ggggaaggaa taaccccgcc atacttaccg
      181 ccgcgccatt tcgcgggttg ccacaaccgg aagcgcacgg tcgaattaaa tttaacgaca
      241 ccgtacagtg agacgaactt cgccgtgcgc tttcgtgttg tatgcctgct tttaaccacg
      301 tcaggcgagg tggtatcctt cttatcccga ataaccaaga aggaaatcta tatgactaaa
      361 gaagaatttg tctcttatat ttttgataaa acggttgaaa tgtatgccgc tacttacggg
      421 tcctgtaatc ctctgaataa accagagggg aaagatgatt tcgacaaaat ttaccgcttc
      481 ttggaggacc gctatatcaa aaggttagag gacgcaggga tcaaatcccc agtgaagtca
      541 ccattgtcct gagaacttgc aggacgtcat gatcgtaact tccatccaaa ccgcgacggc
      601 aaattgcttc tcgtattacc ggaagcagtt cgctggaaat ctcggtgcat atttcacctg
      661 ataatacgcc tggctcaagt gagaatattg gtgaacttac ggtcttggtc tcgacagttt
      721 cagagtcagt gccaacatta taaagctcaa cgaaagcggt cttgattttc cgggccagat
      781 cttttgctgg ctcgcttgca atatctttcc cgatttctcg cagcacagaa tgcaatgtat
      841 gagctgctgt tttctgtaca tcagacggta aatctttaaa ttccatcgtc agcctcatca
      901 gtcagtgttt ctggctaacc agcaacgcgc gccagattcg gttttaaacg ttttgctttt
      961 ggtatatgtc atcgcggtga acgtaccgtc ctggttgggg aacacgccac ataccagaga
     1021 ttcgctgttg ccaagatcga tagtatccat gctgacctca tttcccctta acgccggggt
     1081 agcggaactg tttgctgaga acaccgtgcg gtgtcttgat ggaagtaatt tagttttctc
     1141 attatttttc gtcaaggttt tttgatgaga aaactcaagt attggcgcaa gataaagcca
     1201 atacattgaa atgtaaggct ttaaaatttt gtgaagggat gattattgat gcttgttgcg
     1261 tttgcgagcc tctaatagct cggtgaacag gcgattaaaa ttctcaacgc gggcgcggag
     1321 ttcgctgagt tgtgcttgtt gctctgattt aggaagtgcg cgatacaaac gcagcatctc
     1381 taactcatct tccgataagt ctaaggcact atcgagtgaa acagggggag ctggtgtttt
     1441 gtcctcgtcg ccaaacagta tccaggttgg tgaacattgc aatacctcgg cgaggcgatg
     1501 caaattttgc ccgcgcgggg ctgtatggtc actttcccat aatgaaattg atgagccaga
     1561 tacgccagca gctttgctta aaccgttttg acttaagcct acctgcttac gtctttctct
     1621 aatgcgttga cctaaagttt tctcgttcat atttagatat cttaataacc cttgacttga
     1681 gattccttga gtgattagca ttgagaaaac tcaatattgg aggtgcgatg tttaaatcag
     1741 acgtaattaa tttttacggt acgaaagcca aagtagcgaa agctgctggc gttgacccat
     1801 ctgctgtttc tcaatggcaa gagctggttc ctgaaggtcg cgcgatgcgt ctacaggagg
     1861 catctggcgg cgagcttctg tatgatccca aggtttatga cgaatatcgt aagacgaagc
     1921 gggcggggcg gttgaacaat gaaaatcact cctgaacagg ctcgtgaggc tctggatgcc
     1981 tggatatgtc gaccaggaat gacacagaag caggcgacga tattaatcac tgaagcattc
     2041 tgggctttga aagagcgccc gaacatcgat gttcagcgtg tcacagatga aggtggcgcg
     2101 gttgatcagc gagcgcttgg cgttaatcga gtgaagatat tcgaacgctg gaaggctatc
     2161 gacactaggg ataagcgtga aaagttcacg gcgctagtgc ctgcaattat ggaggctatc
     2221 cggattaatg atttcaggtt gtatcgtgaa attagtgacg gaaaaagcat cacgtacatg
     2281 atcgccgggt taaacaaaga atatggcgat gtggtggagt ccggactgct ttttgctgat
     2341 cctgccgtag tggatcgtga aactgacgaa cttatagaaa aagcaattgc tttcaaactt
     2401 gcgtatcgac agcaatacca acaaaaagct ggatggaatt atgagccttc tttttgctga
     2461 acgcccactg gttataaaca cacagcttgc gatgaagatt ggcttaaatg aagccattgt
     2521 gttgcagcag ttgcattact ggttgagaga taccaattcc ggcatggaat gtgatggtgt
     2581 tcgctggatt tacaacacaa cggaacaatg gctggaacag ttcccattct ggtcagagtc
     2641 aacgttaaag cgcgcgtttg caagtctgaa aacgctgggg cttttgcgtt gtgaaaagct
     2701 caataaatca aagcgcgata tgaccaattt ctacacgatc aactacggga gcgagctttt
     2761 agatggtggc aaattgagcg aatccatcgg tttaaaatgc gccgctccat caggtcaaaa
     2821 tgacacgatg gaagaggtca aaatgaaacg ctccattggt tcaaaacgac ccaatgtcat
     2881 cgggtcaaaa tggcctgatg atcttacaga gaatacaaca gagattacta cagagaataa
     2941 aaacactttt cgtccggaag cttcgcaacc ggacccgcag accgctgaac aggatttttt
     3001 aacccggaac cccgacgcgg ttgtgtttag tgcgaaaaaa cgccagtggg gtagcaggga
     3061 ggatttggcg tgtgcgcagt ggatttgggg gcggatcgtg aacctttacg aacaggctgc
     3121 cagcgacgat ggagagatca tgcgaccaaa agagcctaac tggacagcct gggccaatga
     3181 cgtgcgcaca atgcggatgc tggatggcag aagccacaga caaatttgcg aaatgtttgg
     3241 tcgggtacag cgagatcaat tctgggtaaa aaacatcatg agcccgtcaa aactccgcga
     3301 aaaatgggac gaactggtca tccgcctggg acgttcacct gtacagcgtt gtatgaatca
     3361 tatttctgaa ccggatacag aaattccgcc tggtttcaga ggataagttt tgatttcagg
     3421 tcatgaggta attttaaggg ggacttgtgg caaaagtttt tacacaagaa gagcgggaaa
     3481 aaattaaagg gcaggtggtg gaactcgtgc gccagagcgg tcgtgagacg ttacggcaac
     3541 tggaagctaa aacaggtgcg actagatatc tgatgagcgt tcttgccaga gagctggtag
     3601 ccagtggcga tgtatacaac tccggctacg ggttattccc gtctgaacag gcgcgtaagg
     3661 actggcaaaa cgcccgcaaa aaactatcga gggcaaaggt gaagaaaaca gctgtggttg
     3721 atccggacct tatctggtcg ttacctgatg gagaaatacg tcgctacgac agtcgcctaa
     3781 acataatctg tcgcgagtgc cggatgagtg aagttatgca gcgcatactg gcattttatc
     3841 agggataatg ttaggtattt tagacgttac tagattaaaa agcattagtt caggagtgaa
     3901 ttgacattct catttttcat ggcacagggt agatctggcg tggttgtccg ctttgtgcca
     3961 gaagcggacg ttacaataca atcactatgc taatgcgcat tgatatgtga tataacaata
     4021 atcaaccgtt caaaaaggag catttatatg agcaggatga taattgatac aaatattctt
     4081 tactcactag ttggtctgtc gacaaaccaa aaaataatta actcccctat agatcaattc
     4141 aaattatcca ttacgacacc atcactcata gaagtgatct ctaaatattg caatgactta
     4201 ggggctgtaa aaaaatgcat tagcccaatc ataaacggaa atattgaact aattagcatt
     4261 ggtcatactc caatctcaaa tgaatttctt tataggttgc atttttcaga caaaatagac
     4321 gaagtaaaag atattattga taatgttaga gcactaaaaa tatctagaga ggctgagttt
     4381 tataggttca tactcatact ggttgtctct ggtttgtttg aggttattag agaagatgga
     4441 tacaagtttg ataacgatgt acaaaatcaa agtcaactta gtcttgtgca gactctactt
     4501 gaatctaata tggaattaat tttagacttc tttaaagatg agttgcggaa tggatatatt
     4561 aatggaaatg agcagcaatc agctttgaaa gcttttgaaa ccatgcttat cggactccta
     4621 catgcttttc atgtcaacta tcatatgatt aaaactgaca cagttaacat ttccggaagc
     4681 caagacagac tcaaaaatct gtatgatagt ataaaaaatg ataattttga ta
//
LOCUS       DADXDL010000178         4715 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.178, whole genome shotgun sequence.
ACCESSION   DADXDL010000178 DADXDL010000000
VERSION     DADXDL010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4715)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4715)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4715
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.178"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..671
                     /locus_tag="IRB70_004705"
     CDS             <1..671
                     /locus_tag="IRB70_004705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000409995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBC0634519.1"
                     /translation="KKLSEIDLGDFFNRFNDSMDVAEAELGYGIKCKVQSHKIQPNAQ
                     GTFPTVQINIAFCDRSNASAMKRLESNQSPSVINIDFSFNEKTYDFDFLSLDGDDDND
                     SVKTYSLTDLMAEKYRSVLQQKVRERNREQDIYDINYLLGKYEFSRQDKYKILESLLK
                     KSEGKQLDNLLNVKGIRDVEIIERSSQRYQDLSSTVKSLPLFEDAYEKVACFYESLPW
                     DIFK"
     gene            668..1321
                     /locus_tag="IRB70_004706"
     CDS             668..1321
                     /locus_tag="IRB70_004706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein phosphatase 2C family protein"
                     /protein_id="HBC0634520.1"
                     /translation="MIAFSFSDIGNRCENLDLLSTINCQNDVFGMVIMDGYSCSEWNM
                     KILSGRLDKCVFSGDLNKDIIEPCKSVPVKAAVCFLFKNNTHLHIYNAGDCRVYNKSG
                     VLLTEDNSVAWKRLKENGIDNKKIPHLVCYCPDRNYLTSFVDFCSDEIIFNHSVFDLN
                     DENKEVILCTDGFWEHFNDGTVIDLMKDNPESNLAKFTKNIPGNAENHTVCYVRFPS"
     gene            complement(2310..2504)
                     /locus_tag="IRB70_004707"
     CDS             complement(2310..2504)
                     /locus_tag="IRB70_004707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001041627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rop family plasmid primer RNA-binding protein"
                     /protein_id="HBC0634521.1"
                     /translation="MNKQQQTALNMARFIKSQSLTLLEKLDALDADEQAAMCERLHEL
                     AEELQNSIQVRFETESETGT"
     gene            3580..4536
                     /locus_tag="IRB70_004708"
     CDS             3580..4536
                     /locus_tag="IRB70_004708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634522.1"
                     /translation="MYLIEEALTSWLLNEYKKPVITKEEISLQIYLFYLKKEYNGERI
                     YQIRKNKAGPNEFEKNILKLLKSGVLSRVESNDKHHAYPHLIGGFYEVFFVKGNDGSP
                     ENDIVCSTYPYGYLSYLSAMDWHNITDKIPKIIHFTTCRSEQWKNKFYHDFQKDNPDI
                     DEAKQFMPRFPRNSEVNGIKIIVTQETNYVEPMKARNSPVRVSSIGKTFMDMTRRPDY
                     CGGEEHVLESFIEHGKKYAPLIIKEVDKLGRHIDKVRVGFILDRIIGVNNKKISEWKQ
                     EAGKYRGSSKVLSPKSPFSPYFDEEWFISINVDMVKSYGKRN"
     gene            4520..>4715
                     /locus_tag="IRB70_004709"
     CDS             4520..>4715
                     /locus_tag="IRB70_004709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000409995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBC0634523.1"
                     /translation="MEKEINNWIEESGGKYRLMRQAVHIILKSISIEESLNEMMVMKG
                     GTLLGVKHGSDRYTKDIDFST"
BASE COUNT         1360 a          874 c         1065 g         1416 t
ORIGIN      
        1 aaaaaaaact ttctgaaatt gacttggggg attttttcaa taggtttaat gactcaatgg
       61 atgttgctga ggctgaattg ggatatggta ttaaatgtaa agttcaatct cataaaattc
      121 aacctaatgc acaaggaaca tttccaactg tacagataaa tatagccttt tgcgatcgtt
      181 ctaatgcgtc tgcaatgaaa aggcttgaat ctaatcaatc accttcagtg ataaatatcg
      241 attttagctt taacgaaaaa acgtatgatt ttgacttttt atcattagat ggtgatgatg
      301 acaatgatag cgtaaagacc tacagcttaa ctgatttgat ggctgaaaaa tatcgatccg
      361 ttttgcaaca aaaagttaga gagagaaatc gagagcaaga tatatatgat atcaattatc
      421 ttttaggtaa atatgagttt tctcggcaag ataagtataa aatactggag tctcttttaa
      481 aaaagagtga aggtaaacaa ttggataatc tcttaaacgt taaaggtata agggatgtag
      541 aaattatcga gcgttccagt cagcgatatc aggatttatc atccaccgtt aaatcattac
      601 ctctttttga agatgcttat gaaaaagttg cctgtttcta tgaaagtctt ccgtgggata
      661 tattcaaatg atagcgttca gttttagtga tattggtaac agatgtgaaa acttagactt
      721 attatctacg ataaattgtc aaaatgatgt gtttggaatg gttattatgg atgggtattc
      781 ctgctctgag tggaatatga aaattctctc tggtaggtta gataagtgcg tgttttctgg
      841 tgatctgaat aaagatatta ttgaaccatg caagtcagtt cctgttaagg ctgcagtatg
      901 tttccttttt aaaaataata cgcacctcca tatatataac gcaggagatt gccgtgtata
      961 taacaaaagt ggagtccttc taacagagga taactcggtt gcctggaaaa gattaaagga
     1021 aaatggaatc gataataaaa aaatacctca cctcgtttgt tattgcccag acagaaatta
     1081 tctaacatca tttgttgatt tctgctctga tgagataatt ttcaatcatt cagtttttga
     1141 tttaaatgat gaaaacaaag aggttatttt atgtactgat gggttttggg agcattttaa
     1201 tgatggtact gttattgacc tcatgaaaga taacccagaa tctaacttgg ctaaatttac
     1261 taaaaatatc ccgggtaacg cagagaatca tacggtttgc tacgttagat tcccttcttg
     1321 atttcgtgtt ttttgaagaa gctattgaga tcttcgtgtc atatagataa tctcttttct
     1381 gtaaaagaaa aaaaccgcct ttgcggggcg gttttctctt aggttcaaag agtttgcggc
     1441 tcgaagaacc aaggtaactg gcttggagga gcgcagtcac caaaacctgt tctttcagtt
     1501 tagccttaac tggcgcatga cttcaagact aactcctcta aatcagttac cagtggctgc
     1561 tgccagtggc gttaaggcgt gtcttaccgg gttggactca agacgatagt taccggataa
     1621 ggcgcagcag tcgggctgaa cggggggttc gtgcacacag cccagcttgg agcgaacgac
     1681 ctacaccgaa ctgagatacc aacagcgtga gctatgagaa agcgccacgc ttcccgaagg
     1741 gagaaaggcg gacaggtatc cggtaagcgg cagggtcgga acaggagagc gcacgaggga
     1801 gccaccaggg ggaaacgtct ggtatcttta agtcctgtcg ggtttcgcca cctctgactt
     1861 gagcgtcgat ttctgtgatg ctcgtcaggg gggcggagcc tatggaaaaa cgcctgcggc
     1921 gcggccttct tcctgttctt ggtcttttgc tcacatgttc tttccggcct tatcccctga
     1981 ttctgtggat aaccgtgctg ccgtttttgt gtaagtcagt accgctcgcc gcagccgaac
     2041 gaccgagcgt agcgagtcag tgagcgagga agcggaaaag cgcctggacg cgcattttct
     2101 ccttacgcat ctgtgcggaa tttcacaccc ggcatggggc acttttcata caattcgcac
     2161 tgatgccgca tagttaagcc agtatacact ccgctatcgc tacgtgactg ggtcagggct
     2221 tcgccccgac acccgctgac gcgccctggc gggcttgtct gctgccgaaa acgctcgcgg
     2281 acaagccgtg agcgcctccg tcagcttcgt tatgttcctg tttcactttc ggtctcaaag
     2341 cgaacctgga tgctgttctg gagttcttcc gcgagttcgt gcagtcgttc gcacatggcc
     2401 gcctgttcgt cggcatccag agcatccagt ttttcaagca gtgtcaggct ctggcttttg
     2461 ataaatcgcg ccatattcag cgcagtttgt tgctgtttgt tcaccttccg ttgttctccg
     2521 tcagtaccgg gtgtcgggtg gaccctgacc aggtggtaat tgtaagacgt tgcgggcgac
     2581 ggtattacaa ttgcacatcc tgtcctgttt ttttaggacg tatcatggca cagcatatca
     2641 actgataaat aatccctgtg cagtgcagcc gctgttgcat aaaatttcgc tctgcgtcga
     2701 gtgtttctta atcaataatt ccgctgatac tccggaaaaa cgcgagtctg ttctcatgcc
     2761 tgaaatgccc acaccccacg caaaaacaag tttttgctga tttttcttta taaatagaga
     2821 gttatgacaa attagttctt cttgctctct ttgtgatatt taaaaaagcg gtgtcggcgc
     2881 ggtgttgtag ctgcgccaac accgcttttt aggggtggta ctgactattt tcataaaaaa
     2941 catcatctta tattaggggt gctgctagcg gcgcggtgtg tttttttaca ggacacccct
     3001 gggggcgctg ctaggggtgt ctgttcagat atgtagcaat gagtcaggga ttcacgaact
     3061 gaaaatgtcc gaaaatgtgt ctcatgggca ctgtatgcgc ccaaaccgat cgtcattcac
     3121 tttcatgcat agctatgcag tgagctgaaa gcgatcctga cgcatttttc cggtttaccc
     3181 cggggagaac atctcttttt gcggtgttcg cggcagaatc gctttcagcg cgttttagcg
     3241 gtgcgcgcaa tgcgacgtta tggtaaatga cgctgaaaaa tgatctttta cgctcatcgt
     3301 ttatgagcaa cagatgtcct aatcatggat ttgaactata accgccgctg aattgatcgc
     3361 atgaggtgtt atgaaaacgg tgatataagt aaactttttc ttgacttcct acttattatc
     3421 ctataaaata aatccttagg atttatttta taggatatca aaaatataaa aatggcaaat
     3481 gcttgtttgt tattattttt ttcttgacaa tcaatctcta atagaatata cgtccttagg
     3541 acgtatattc tattagagac taaaccgaaa aggttgaata tgtatcttat cgaagaagcg
     3601 ctaacgtctt ggttgttgaa tgaatataaa aaaccagtca taaccaaaga agaaatctct
     3661 ttgcagattt acctttttta tttaaaaaaa gaatataatg gtgagaggat atatcaaatt
     3721 agaaagaaca aagcaggacc taatgaattt gaaaaaaata tattaaaatt attaaagtca
     3781 ggggttttat caagagttga aagtaacgat aagcatcatg cttaccccca tttaattggc
     3841 ggtttctatg aggtcttttt tgttaaaggt aacgatggtt ctccggaaaa tgatatagtg
     3901 tgctctacgt atccatatgg atacttatcc tatttatccg ctatggattg gcataacatc
     3961 acagataaaa tacccaagat aatccacttt acgacatgtc gttccgaaca gtggaagaat
     4021 aagttctatc atgattttca aaaggataat cctgatatag acgaagccaa acaattcatg
     4081 cctagatttc caagaaattc tgaggtcaat ggaataaaaa ttatcgttac acaagaaaca
     4141 aattatgttg agccaatgaa ggctcgtaat tcccctgtca gggtatcatc tatcggtaag
     4201 acctttatgg atatgaccag gcggcctgat tactgtggtg gtgaggagca tgtattggaa
     4261 tcatttattg agcacggtaa aaaatatgca cctctgatta taaaggaagt cgataagctt
     4321 ggccgtcata ttgacaaggt aagggttgga ttcattttgg atagaattat tggggttaat
     4381 aataaaaaaa taagcgaatg gaaacaagag gcgggtaaat acagaggtag ttcgaaagtg
     4441 ctatctccaa agagtccatt ctcaccttac tttgatgaag aatggtttat ttctattaat
     4501 gttgatatgg ttaagtctta tggaaaaaga aattaataat tggatcgaag agtctggtgg
     4561 gaagtacagg ttgatgcgcc aggctgtaca tataatactt aaatctattt ctatagagga
     4621 gagtttgaat gaaatgatgg ttatgaaggg agggactctt cttggtgtta agcatggtag
     4681 tgatagatac acaaaggata ttgatttttc taccg
//
LOCUS       DADXDL010000179         4591 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.179, whole genome shotgun sequence.
ACCESSION   DADXDL010000179 DADXDL010000000
VERSION     DADXDL010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4591)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4591)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4591
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.179"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(220..633)
                     /locus_tag="IRB70_004710"
                     /pseudo
     CDS             complement(220..633)
                     /locus_tag="IRB70_004710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015377870.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
     gene            631..888
                     /locus_tag="IRB70_004711"
                     /pseudo
     CDS             631..888
                     /locus_tag="IRB70_004711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            complement(1122..1979)
                     /gene="sitD"
                     /locus_tag="IRB70_004712"
     CDS             complement(1122..1979)
                     /gene="sitD"
                     /locus_tag="IRB70_004712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitD"
                     /protein_id="HBC0634524.1"
                     /translation="MMALLLEPLQFTFMSHALLISLVVSIPCALLSVFLVLKSWALMG
                     DAMSHAVFPGIVLAWILGLPLATGAFVAGVFCAVATGYLKDNSRIKQDTVMGIVFSGM
                     FAAGLILYIAVKPDVHLDHILFGDMLGITIGDIIQTVIIAGLVTLVISVKWRDFLLFS
                     FDYQQAQASGLHTRWLHYGLLCMVSLTIVATLKAVGIILSISLLIAPGAIAVLLTQRF
                     HIALLLATGISILVSMTGVWLSFFIDSAPAPTIVVLFAVMFIMTFTVTSINARTKENA
                     EPRDLLSSD"
     gene            complement(1976..2833)
                     /gene="sitC"
                     /locus_tag="IRB70_004713"
     CDS             complement(1976..2833)
                     /gene="sitC"
                     /locus_tag="IRB70_004713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter permease subunit
                     SitC"
                     /protein_id="HBC0634525.1"
                     /translation="MNVLLEPFSYEYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGD
                     ALSHSIVPGVAGAYMLGLPFSLGAFFSGGLAAGSMLFLNQLTRLKEDAIIGLIFSSFF
                     GLGLFMVSLNPTSVNIQTIVLGNILAIDPADILQLTIIGILSIIVLFFKWKDLMVTFF
                     DENHARAIGLHPGRLKILFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFP
                     RLLMIAVTIGSVTSFLGAWVSYFLDGATGGIIVVAQTLLFLLAFVFAPTHGLLANRRR
                     AHKALEDRS"
     gene            complement(2830..3657)
                     /gene="sitB"
                     /locus_tag="IRB70_004714"
     CDS             complement(2830..3657)
                     /gene="sitB"
                     /locus_tag="IRB70_004714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter ATP-binding
                     protein SitB"
                     /protein_id="HBC0634526.1"
                     /translation="MMQSAGIVVNDVTVTWRNGHTALRDASFTVPGGSIAALVGVNGS
                     GKSTLFKAIMGFVRLTSGKISVLGIPTRQALQKNLVAYVPQSEEVDWSFPVLVEDVVM
                     MGRYGHMGMLRIAKKRDRQIVTDALERVDMVDFRHRQIGELSGGQKKRVFLARAIAQQ
                     GDVILLDEPFTGVDVKTEAKIISLLRELRAEGKTMLVSTHNLGSVTTFCDYTVMVKGT
                     VLASGPTDTTFTAENLELAFSGVLRHVTLNGSEESIITDDERPFVAHRPSAVQREER"
     gene            complement(3657..4571)
                     /gene="sitA"
                     /locus_tag="IRB70_004715"
     CDS             complement(3657..4571)
                     /gene="sitA"
                     /locus_tag="IRB70_004715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000949004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron/manganese ABC transporter substrate-binding
                     protein SitA"
                     /protein_id="HBC0634527.1"
                     /translation="MLSIKKVTMLLGCLVLTCSIAFQASAAEKFKVITTFTIIADMAK
                     NVAGDAAEVSSITKPGAEIHEYQPTPGDIKRAQGAQLILANGMNLELWFQRFYQHLNG
                     VPEVIVSSGVTPVGITEGPYEGKPNPHAWMSPDNALIYVDNIRDAFIKYDPANAQTYQ
                     RNADTYKAKITQTLAPLRKQIAELPENQRWMVTSEGAFSYLARDLGLKELYLWPINAD
                     QQGTPQQVRKVVDIVKKNHIPAVFSESTISDKPARQVARETGAHYGGVLYVDSLSTEN
                     GPVPTYIDLLKVTTSTLVQGIKAGKREK"
BASE COUNT         1242 a         1188 c         1074 g         1087 t
ORIGIN      
        1 ttaataccct cgacaattgc tgagcagaag cccccacgac aagtgacaga atgacaacat
       61 ctacagtggg gagcgtttta tcgatgaaca agcaaccaag aagtaacacg gcataggtga
      121 cgacaatgcc agtaagcata gaaataacaa aaacgtgagc tttcatcatt cctccagaat
      181 aaccccgacg tgtaagcctg ggggattggc acaataatgt catttaaagg cagactttcc
      241 ggcaaattgc gccgatgaac ccagttcatc ctcaattctc ataagctggt tatatttttc
      301 aatacgctca ccccggcatg gagctcccgt tttgagatga cctgcgcgca ttgcaactgt
      361 catatcggcg ataaagctgt ccactgtctc accactgcgg tgtgagataa aggtgcccca
      421 gttgttgtca tggcaaagtt gtaccgcatc aaaggtttca ctcagggaac caatctggtt
      481 gagtttaatc aatgctgaat tggcaaggtt ttcgtcaatg ccgcgctgaa tatactttac
      541 gttggtcaca aacagatcgt cgccaaccaa ttctatctgc tctcccaatg caccatgcag
      601 gattttccat ccagcccagt catcttcagc taccgttaag ggcaggaaga tcaactaggt
      661 gctctggggc tggtgaccaa tgcggttgtg ctgtgaaaca cactttacat gcaggaggcg
      721 ttgtcacatc ttcgcaaatc gggagaaact cctgaggagt agcatccggc aagattatcg
      781 ctgctgatac atagccatat aaatatgctg gggcattata cgtcttcgtt accggaagat
      841 attcttaagg gtgagttaag atcattaaac ttcaatacaa acaattaatt aaactcttag
      901 cgtggttttt tacatcactg gccctcgccc cccaattttc tctatgtttt gccactactt
      961 ccctcatttt actgcgctgt ttgctacccc tgagaatcga cattacttgc tatccagtcc
     1021 gcagcaactc tctggcaaca aaacttatca gaatcataag tctgtgcatt attcgttcaa
     1081 gcgcatcgcc aataagcgga tgttgctggc cgagtgttct gctaatcgga tgataacaaa
     1141 tcccgtggtt cggcattttc ctttgtgcgt gcgttgatgc tggtaacggt aaacgtcatg
     1201 atgaacatga ccgcgaataa gacaacaatt gtcggagctg gcgcgctgtc gataaaaaag
     1261 gacagccaga caccagtcat tgagaccaat atcgatatgc cagtcgccag caggagcgca
     1321 atatgaaagc gttgtgtcag gagtaccgca atggcaccag gcgcaatgag aagagaaata
     1381 gagagaatga tacctaccgc tttcagcgtc gccacaatgg tcagggagac catgcacagc
     1441 agcccataat gcagccatct cgtatgcaaa ccgcttgcct gcgcctgttg ataatcaaag
     1501 ctgaacagca aaaaatcccg ccattttacg ctaataacaa gtgtaaccag tccggcaata
     1561 atcaccgtct ggattatatc gccgatggtt atcccgagca tgtcgccgaa aagaatatga
     1621 tcaagatgta cgtctggttt gactgcaata tacaagatca gacctgcggc aaacatgcca
     1681 gaaaaaacaa tccccatcac tgtatcttgc ttgattcggc tgttgtcttt caggtatccc
     1741 gtcgccaccg cacagaatac tccggcgacg aatgcccctg tagccagagg taaccccaga
     1801 atccaggcaa gcacgatgcc aggaaaaacc gcatgactca tcgcgtcacc catcagtgcc
     1861 caacttttca ggaccagaaa gaccgacagc agcgcacagg gtatggaaac aaccagtgaa
     1921 atcagcagtg cgtgactcat aaaggtgaac tgcagtggct ccagtaataa tgccatcatg
     1981 agcgatcctc cagcgcttta tgcgcacgcc gacgatttgc caaaagccca tgggtgggcg
     2041 caaagacaaa tgctaaaaga aacagcagtg tctgcgccac cacgatgatt ccacctgtcg
     2101 cgccgtccag aaagtaactg acccacgcgc cgaggaaact ggtcacactg ccaatagtta
     2161 cagcaatcat gagcaggcgg ggaaaacgat cggttaacaa ccatgctgtt gcaccgggag
     2221 tcaccaccag acagatcacc agaaaggcac caaccgtttg cagcgccgca acggtcgaaa
     2281 ccgacagcag ggtgaagaag aggattttta atctgcccgg atgcaatcca atagcacggg
     2341 cgtgattctc gtcgaaaaag gtcaccataa gatctttcca tttgaaaaaa agcacgatga
     2401 tcgagagaat gccaatgata gtgagttgca ggatatccgc cggatcgatt gccagaatat
     2461 tgcccaggac gatggtctga atgttcacgg atgtcgggtt caatgacacc ataaacagcc
     2521 ccaggccaaa aaaggacgag aagatcaggc cgatgatggc atcttctttt aagcgagtga
     2581 gttggttaag aaacagcatg ctgcccgctg ccagtccgcc ggaaaagaag gctcccagag
     2641 aaaacggaag ccccagcata tatgcccccg caacacccgg gacaatagag tgcgacagcg
     2701 catcgccaat cagcgaccag ccttttagca tcagatagca tgacaggaaa gcgcagagac
     2761 cgccgaccat cgccgagacc cacatcgcat tgagcatata ttcatagctg aagggttcca
     2821 gtagcacgtt catctttctt ccctctgcac cgctgacggt cgatgtgcca caaaagggcg
     2881 ttcatcgtca gtaataatgc tttcttccga gccgttaagt gtgacatggc gcagtacgcc
     2941 gctaaaagcc agctccaggt tctcggctgt aaaagtggtg tctgtcggcc cgcttgccag
     3001 gacggtgcct ttgaccatga ccgtataatc gcaaaatgtc gtgacggatc cgagattgtg
     3061 cgttgagaca agcatcgttt tgccttccgc gcgtaactcc ctcaacaggc tgatgatttt
     3121 cgcttcggtt ttcacatcaa cgccggtaaa aggttcatcc agcaggatca catcaccctg
     3181 ctgtgcaatc gctctcgcca gaaagacgcg tttcttttgt ccaccggaaa gctcgccgat
     3241 ttgtcgatgg cgaaaatcca ccatatcgac acgttccagc gcatcggtga caatctgacg
     3301 atccctcttt ttggcgatac gcaacatacc catatgccca tagcggccca tcatcaccac
     3361 atcttccacc agtacaggaa atgaccagtc aacctcttct gactgaggga cgtaggcaac
     3421 caggtttttc tgtagcgcct gtcgtgtggg aatacccaga acagatatct tcccgctggt
     3481 cagacgcaca aatcccataa tcgctttaaa caacgtcgat tttccggaac cgtttacccc
     3541 aaccagagcg gcaatagatc cgcctggtac tgtgaaggat gcatcgcgca gtgctgtgtg
     3601 cccgttacgc caggtgacag taacatcatt aacgacaatg cctgcagatt gcatcattat
     3661 ttctcccttt ttccggcttt aattccctgt accagcgtac tggtagtaac cttcagaagg
     3721 tcgatatacg taggtaccgg gccgttttct gtgctcaggg aatcgacata gagcacacca
     3781 ccgtagtgcg cgccggtttc acgcgcaacc tgacgcgctg gtttatcgga aatcgtactc
     3841 tcgctaaaga ctgccgggat atgatttttc ttaactatat caacaacctt acgtacctgc
     3901 tgcggtgttc cttgttgatc ggcattaatc ggccacagat aaagctcttt tagccccaaa
     3961 tcgcgtgcga gataagaaaa agccccttca ctggtgacca tccatcgctg attctcaggg
     4021 agttccgcaa tctgcttacg caggggggca agggtttggg taatcttggc tttataagta
     4081 tcggcattac gttggtaggt ttgtgcattt gccggatcgt attttataaa cgcatcacga
     4141 atattatcga cgtaaatcag agcattatct ggcgacatcc aggcatgggg gttaggtttg
     4201 ccctcatagg gcccttcggt gatccctact ggcgtcacac ccgaagagac aattacttct
     4261 ggaaccccat tgagatgctg gtaaaagcgt tggaaccaca attccagatt cataccattg
     4321 gcgagaatca gttgtgcccc ctgcgcacgt ttaatatcgc caggggtagg ctgatactca
     4381 tgaatttctg caccaggctt ggttatggat gagacttctg cagcatctcc agccacgttt
     4441 ttggccatat ctgcgatgat ggtaaaagtt gtaatgacct tgaatttttc agctgcactc
     4501 gcctgaaatg ctatcgagca ggtgaggact aggcacccca agagcatggt tacttttttt
     4561 attgagagca tgatttagta cctatagtga g
//
LOCUS       DADXDL010000180         4586 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.180, whole genome shotgun sequence.
ACCESSION   DADXDL010000180 DADXDL010000000
VERSION     DADXDL010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4586)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4586)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4586
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.180"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            321..506
                     /locus_tag="IRB70_004716"
     CDS             321..506
                     /locus_tag="IRB70_004716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000833473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicA family
                     toxin"
                     /protein_id="HBC0634528.1"
                     /translation="MKSADVIAILKQHGWEHIRTRGSHHQFRHPVHPGLVTVPHPKKD
                     IKPGTLAQIGRQAGLTF"
     gene            523..933
                     /locus_tag="IRB70_004717"
     CDS             523..933
                     /locus_tag="IRB70_004717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000499746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system HicB family
                     antitoxin"
                     /protein_id="HBC0634529.1"
                     /translation="MFYPAYIHSDPDGSASGFFPDVPGCYFAGDTLDNAFQDARSALA
                     AHFETLCEMDEELPLPGSVETHLVQRAQDFIGGQWLLVDINMNQFEGRAERINITMPK
                     RLLNKIDTYVRNNPDYANRSAFLAEAARRVLPGV"
     gene            complement(1045..3024)
                     /locus_tag="IRB70_004718"
     CDS             complement(1045..3024)
                     /locus_tag="IRB70_004718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003581012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 127 protein"
                     /protein_id="HBC0634530.1"
                     /translation="MNISEVDLHKLTVSDPFLGQYQQLVRDVVIPYQWDALNDRIPEA
                     EPSHAIENFRIAAGLQEGEFYGMVFQDSDVAKWLEAVAWSLCQKPDAELEKTADEVIE
                     LIASAQCEDGYLNTYFTVKAPEERWSNLAECHELYCAGHLIEAGVAFFQATGKRRLLE
                     VVCRLTDHIDSVFGPGESKLHGYPGHPEIELALMRLYEVTEEPRYLALTNYFVEQRGA
                     QPHYYDQEYEKRGQTSHWHTYGPAWMVKDKAYSQAHLPIAQQQTAIGHAVRFVYLMTG
                     VAHLARLSHDESKRQDCLRLWNNMAQRQLYITGGIGSQSSGEAFSSDYDLPNDTVYAE
                     SCASIGLMMFARRMLEMEGDSQYADVMERALYNTVLGGMALDGKHFFYVNPLEVHPKS
                     LKFNHIYDHVKPIRQRWFGCACCPPNIARVLTSIGHYLYTPREDALYINIYAGNSMEV
                     PVENGTLRLRVSGNYPWQEQVTIAVESPQPVRHTLALRLPDWCTQPQIILNGEEVEQD
                     IRKGYLHITREWQEGDTLNLTLPMPVRRVYGNPLVRHVAGKVAIQRGPLVYCLEQADN
                     GESLHNLWLPADAPFTTFEGNGLFRHKILIQAPGYRYEQSNPEQQPLWHYDSAPAKRQ
                     PQTLTFIPWFSWANRGEGEMRIWVNEEKHCHPEVG"
     gene            complement(3035..4435)
                     /locus_tag="IRB70_004719"
     CDS             complement(3035..4435)
                     /locus_tag="IRB70_004719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0634531.1"
                     /translation="MTSTPITAADIAKGKIDDALSVREKIGYGLGDAGGTVITCLIMN
                     FLTFFYTDVFGLTPALVGTLFIALRVFDAISDPVMGVIADRTQSRWGRFRPWQLWIAI
                     PIGIIGILTFTVPDASMGVKIAWAFGTYLLLSVGYTAINVPYCALINTMTTRHNEVIS
                     CQSWRFVLCGVAGFLVSVGLPWMVDLFGQGNAARGYQLGVGVLCAIAVVMFLCCFFWV
                     RERVPLSTMGKFTLREHLAGLRNNDQLLLMLVMSFLLINVFNIRGGGYMYFITYVLQG
                     STGYTSLFFTMVTFASIIGSVIVSPLTRRFDTVKIYYYTNLLLAALAVLMWFLPSGPA
                     YQTLWLAVILGNGVILGFTLPLHFSLMAFADDYGEWKTRVRSSGMNFAFNLFFIKLAW
                     ASSAGIISLLFIFVAYQPGVENQTASSLGGITAMETLLPALFHLLLAMAIRFCKLNNP
                     MMSRIASDLRQRHVQP"
BASE COUNT         1117 a         1198 c         1209 g         1062 t
ORIGIN      
        1 atatttatca agaaaataaa acaatgtctt ttattggttg ttttaaatgt tcaatgaata
       61 cgagttggaa ctatagcaag actagcttcg atatcgcatg gataatctaa tacagatttt
      121 ttaacaccta atactatgag ttatatgtaa attgcgagca tcctcgcata ttttctacca
      181 attactgcac accgttattc ttcttccgag cggcattcct gagtcaactt tatccccctg
      241 acggcccata taaatcgcgc tatcgtgatt gttatcacta attgtgtgtg tcgtgtgtat
      301 aatcatggaa gggcagggat gtgaaaagtg cagacgtgat cgccatcctg aagcagcatg
      361 gctgggaaca tattcgaacc cgtggcagtc atcatcagtt ccgccaccct gttcatccgg
      421 gtctggtgac ggttccgcac cctaaaaaag atattaagcc cggtacgctg gcgcaaattg
      481 ggcgtcaggc tggtttaaca ttttaaaatt tcaggaggca atatgtttta tcccgcctat
      541 atccacagtg atcctgacgg cagcgccagc ggttttttcc ctgatgttcc aggctgttat
      601 tttgctggtg atacgctgga caacgctttc caggatgcgc gaagtgcact ggccgcgcac
      661 ttcgaaacct tatgcgagat ggatgaagag ttgccgcttc caggctctgt ggaaacacat
      721 ctggtccagc gtgcgcagga ctttattggc gggcaatggt tgctggtgga tatcaatatg
      781 aatcagttcg aaggtcgggc tgaacgtatc aatattacga tgccgaaaag gttactgaac
      841 aagattgata cctacgtgcg caataaccca gactacgcca acagaagtgc gtttctggca
      901 gaagctgccc ggcgtgtatt gccgggcgtt taatctcgcg tttcgatggt tagcgggcaa
      961 ctgcaccgac tcgtgggcct gataagacgt gttaagcgtc gcatcaggca atgtgctccc
     1021 tacgttggat gcggcgcgag cgccttatcc aacctccgga tggcaatgct tttcctcatt
     1081 cacccagatc cgcatttcgc cttcaccccg gttagcccag ctaaaccacg ggataaacgt
     1141 cagagtttgc ggctggcgtt tggctggcgc actgtcgtaa tgccacagcg gttgctgctc
     1201 tggattgctc tgttcatacc ggtaacccgg tgcctggatt aagatcttat ggcggaacaa
     1261 tccattacct tcaaatgtcg taaatggcgc atcggcgggc agccacaggt tatgcagtga
     1321 ctcgccgttg tcggcctgtt ccaggcaata caccagcggg ccgcgctgaa tcgccacttt
     1381 tccggcgacg tgacgcacca gcgggttacc gtaaacgcga cgtaccggca ttggcaacgt
     1441 cagattcagc gtgtcgccct cctgccattc gcgggtaatg tgcaaatacc ctttacgaat
     1501 atcctgctcg acctcttccc cattcaatat gatctgcggc tgtgtgcacc agtccggcag
     1561 acgtaaagcc agcgtatgac gcaccggctg gggcgattca accgcaattg tcacctgttc
     1621 ctgccacgga tagttcccgc taacccgcag gcgcaacgtg ccattttcta ccggcacttc
     1681 catgctgttt cctgcgtata tgttgatata caacgcatct tcacgcggcg tgtagagata
     1741 atgaccaatc gaggtcagta cgcgggcgat atttggcgga caacaagcgc agccaaacca
     1801 acgctggcgg atcggcttaa cgtgatcgta gatatggttg aatttcagcg attttggatg
     1861 tacttccagc ggattcacat agaagaaatg tttgccatcc agtgccatgc cgccgagcac
     1921 agtgttgtac agcgcgcgct ccatcacatc ggcatattga ctgtcgcctt ccatttccag
     1981 cattcgtcgg gcgaacatca tcaggccgat ggaagcacaa ctttcggcgt aaaccgtgtc
     2041 attcggcaga tcgtaatcgc tgctgaacgc ttcgccgctg ctttgtgagc caatgccgcc
     2101 ggtaatatat aactgacgct gggccatatt gttccacagc cgcaggcagt cctgacgctt
     2161 gctttcatcg tgacttaaac gggcgagatg cgcgacgccg gtcatcaggt agacaaaacg
     2221 taccgcgtga ccaatggcgg tttgctgctg tgcgatgggc aaatgtgcct ggctgtaggc
     2281 tttgtctttc accatccacg ccgggccgta ggtgtgccag tgcgaggtct gcccgcgctt
     2341 ttcatattcc tggtcgtaat agtgcggttg cgcaccacgc tgttcgacaa aatagttcgt
     2401 cagcgccagg tagcgcggct cttcggtcac ttcatacagg cgcattagtg ccagttcaat
     2461 ttccgggtga ccaggataac cgtgtaactt actttcacct ggaccaaata cgctgtcgat
     2521 atgatcggtc agacggcaaa ccacttccag caagcgccgc ttgcccgtgg cctggaagaa
     2581 ggcgactccg gcttcaatca gatgaccggc gcagtaaagt tcatggcact ccgccagatt
     2641 gctccagcgt tcttcgggcg cttttaccgt aaagtaagta ttgagatagc catcttcgca
     2701 ctgggcggaa gcgatcagtt caatcacctc gtcggcggtt ttttccagtt cggcgtccgg
     2761 cttctggcac agcgaccagg ctaccgcttc cagccatttg gcgacgtcgc tgtcctgaaa
     2821 caccatcccg taaaattcac cctcctgaag tccggcggca atgcgaaagt tttcaatcgc
     2881 atggctgggt tccgcttctg ggatacgatc gttcaaggca tcccactgat aaggaatcac
     2941 cacgtcgcgg accagttgtt ggtactgacc gaggaacgga tcgctgaccg tcagtttatg
     3001 cagatcgact tccgaaatgt tcatcttgtg ctccttaagg ctgtacatga cgctgacgca
     3061 ggtcgctagc aatgcgtgac atcatagggt tattgagttt gcaaaagcgg atcgccatcg
     3121 ccagcagcag gtggaacagc gcaggcagca atgtttccat tgctgtgatc ccgccaagcg
     3181 aactggcggt ctggttttcc acgcctggct ggtaggcgac aaaaataaac agcaggctga
     3241 tgatcccggc gctggaggcc caggccagtt tgatgaaaaa cagattgaag gcgaagttca
     3301 tgccggaaga acgtacgcgg gttttccact cgccgtagtc atcggcaaag gccatcaatg
     3361 agaagtgcaa tggcaatgtg aagccaagaa tcacgccatt accgaggatc accgccagcc
     3421 acagcgtttg ataagccggg ccagaaggca ggaaccacat caacaccgcc agcgcggcga
     3481 ggagcaggtt ggtgtagtag taaattttga cggtatcgaa acgccgcgtt aacgggctga
     3541 caatcaccga gccgataatg gaggcgaagg tgaccatagt gaagaacagc gacgtgtagc
     3601 ccgtactgcc ttgtaagacg taggtaatga agtacatata cccaccgccg cgaatattaa
     3661 agacgttaat cagcaggaaa gacatgacca gcatcagcag cagttggtcg ttgttccgca
     3721 gcccggcaag atgttcgcgc agggtaaatt tccccattgt ggagagtggc acccgttcac
     3781 gaacccagaa gaaacagcac aggaacatca ccacagcgat ggcgcacagc acgccgacgc
     3841 ccagttgata gccgcgcgcg gcattaccct gaccgaagag atccaccatc cacggtaagc
     3901 ctaccgaaac cagaaatccc gctacgccgc agagaacgaa tcgccaggac tggcaggaga
     3961 tcacttcatt gtggcgggtg gtcatggtgt tgatcagcgc gcagtacggt acgttgatgg
     4021 cggtataacc gactgaaagg agcaggtaag taccgaacgc ccaggcgatt tttactccca
     4081 tgctggcatc tggcacggtg aacgtcagga tgccgataat gccgatggga atggcaatcc
     4141 acaactgcca cggacgaaag cgcccccagc gactttgcgt ccggtcggca atgacgccca
     4201 tcaccgggtc ggagatggca tcaaacacgc gcagtgcaat aaacagcgtg ccgaccagcg
     4261 ccggagttaa gccaaaaacg tcggtgtaga aaaaggtgag aaagttcatg atcaggcaag
     4321 ttattacggt gccgcctgcg tcacccaggc cgtagcctat tttttcccgt acagataacg
     4381 catcgtcaat tttaccttta gcgatatcag cggcagtaat cggtgtagag gtcatagata
     4441 ttcctcgtga atagggagca atttttagtt ttattgcaat gacctgatta attctgccgt
     4501 gaacgggaat atcaacaagg cgagaaaaga gtaaaaaaag gtgacgattc cgacctgaat
     4561 ttaaaagtgt gaaatggatc aggtga
//
LOCUS       DADXDL010000181         4568 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.181, whole genome shotgun sequence.
ACCESSION   DADXDL010000181 DADXDL010000000
VERSION     DADXDL010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4568)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4568)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4568
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.181"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1..318
                     /locus_tag="IRB70_004720"
                     /pseudo
     CDS             1..318
                     /locus_tag="IRB70_004720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612230.1"
                     /note="internal stop; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1-like element IS1F family transposase"
     gene            complement(338..403)
                     /locus_tag="IRB70_004721"
                     /pseudo
     CDS             complement(338..403)
                     /locus_tag="IRB70_004721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000280980.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="omptin family outer membrane protease"
     gene            636..740
                     /locus_tag="IRB70_004722"
                     /pseudo
     CDS             636..740
                     /locus_tag="IRB70_004722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477168.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            1080..1337
                     /locus_tag="IRB70_004723"
     CDS             1080..1337
                     /locus_tag="IRB70_004723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016230781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biofilm development YmgB/AriR family protein"
                     /protein_id="HBC0634532.1"
                     /translation="MHSDYYNMVFGEKLANILYEANSQFFYERNVIEEAVNALFCERE
                     IINNKNIIKKLMFFLSDVNHTKKDVVQSALNIIIDITSGDI"
     gene            complement(1657..1788)
                     /locus_tag="IRB70_004724"
                     /pseudo
     CDS             complement(1657..1788)
                     /locus_tag="IRB70_004724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     gene            2070..3428
                     /locus_tag="IRB70_004725"
     CDS             2070..3428
                     /locus_tag="IRB70_004725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000823236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase-like activity of phytase family
                     protein"
                     /protein_id="HBC0634533.1"
                     /translation="MKRKIIPVLIGCTLSFSALAAQPTAERYVVSFPEGTHVNYAGAF
                     ASAFPNGLPVGIGSGLLFTGKQGDALTFATITDRGPNADSPKEGKNETKIFVTPDFAP
                     LLMTIRVQNGKAEAIDPRPLHDDKGAINGLPLASDVIGSTNEVAFSDTLHRLKGDNRG
                     LDTEGITPDGKGGYWLCDEYGPFLINIDSKGKILAIHGPQAAEGEKAIAGGLPNILKW
                     RQANRGFEGLTRMPDGRIIVAVQSTLDIDAKSKKKALFTRLVSFDPASGKTAMYGYPI
                     DSAAYSKSSDAKIGDIVALDNQHILLIEQGRDKNNRMRNLIYEVDLNKASDLSGFDKP
                     GEYPEFDDEKTLSQRGITLAQKTQVVDLRSLGWQQEKAEGLALIDSKTLAVANDNDFG
                     VKVAMQHPVEGKTFKDYRVNAEGKLTLDDKQVETTLRVKPLEKPESDSELWIVTLPEA
                     LK"
     gene            complement(3667..>4568)
                     /locus_tag="IRB70_004726"
     CDS             complement(3667..>4568)
                     /locus_tag="IRB70_004726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBC0634534.1"
                     /translation="IVQAPAPSRPIERGIAGPGLLARVLTSKYAEHTPLYCQSEIYGR
                     QGVELSRSLLSGWVDACCRLLSPLEEALHGYVMTDGKLHADDTPVQVLLPGNKKTKTG
                     RLWAYVRDDRNAGSALAPAVWFAYSPDRKGIHPQTHLACFSGVLQADAYAGFNELYRN
                     GGITEAACWAHARRKIHDVHVRIPSALTEEALEQIGQLYAIEADIRGMPAEQRLAERQ
                     RKTKPLLKSLESWLREKMKTLFFGSGHGGERGALLYSLIGTCKLNDVDPESYLRHVLG
                     VIADWPVNRVSELLPWRIALPAE"
BASE COUNT         1207 a         1108 c         1138 g         1115 t
ORIGIN      
        1 tatgacagga tacggaggac ggttgtggcg cacgtcttcg gtgaacgcac tctggccaca
       61 ctggagcgtc ttctgagcct gctgtcggcc tttgaggtcg tggtatagat gacggatggc
      121 tggccgctgt atgaatcacg cctgaaggga aagctgcacg ttatcagcaa gcgttacact
      181 cagcgcattg agcgacataa tctgaatctg agacaacatc tggcaaggct gggacggaag
      241 ttactgtcgt tctcaaaatc ggtggagttg catgacaagg tcatcgggca ttatctgaac
      301 ataaaacact atcagtaagt tggagtcatt acctcctccc gaactcaaag ctatcataca
      361 gataattact ggttaaccct atatagggca ttttaaagtg ttgtgatctt acccagcaat
      421 agtggacacg cggctaagtg agtaaactct cagtcagagg tgactcacaa gacaaaacag
      481 tttcaaccag taaaaaaacg taaacaccat tcgcatgaat ttcgtagtta agatctgaag
      541 cttgcagaat gcatcggtgt tactgccgga gtccgtgaac ttagtctgca tgaatcacca
      601 cagctttaca tctgtcgcag taaacagcaa aatcagcaaa cttacttaat tatatcgagt
      661 gcgattacaa tcgctggcga tggtacagtt ggtgtggcgg tctcagtccg gaacaatttg
      721 aaaatcagaa tctcacttaa aacggcatcc attttacaaa agatggccgt ctgtgtattt
      781 gtaatgaata ccttctacat gtttagagtg cataatccac gacaaggcga tatcctaaaa
      841 attagctagc aggcaacttt gatggcatag ataatatttt tagtaaaaaa gagttgactg
      901 aatataatac agcctcttcc tacataagaa ggaatgtgct cacaaaaaaa aaccattagt
      961 ctgcttcctg ttcttacaat aatcagtatt atgtatttta tttatatagc aaaatatgct
     1021 tgttacacct gtcataatta ggcatggtaa aattattgac tgaaccctgg gggagaaaga
     1081 tgcacagtga ttattataat atggtttttg gtgaaaaatt ggccaatatt ttatatgaag
     1141 ctaactctca atttttttac gagagaaatg tcatagaaga ggcagtcaac gctttattct
     1201 gtgagcgtga aataataaac aacaagaaca taataaagaa gctgatgttc tttttgtcag
     1261 atgttaatca caccaagaaa gatgttgttc agagcgcact taatattatc attgacatta
     1321 catcaggtga tatttgagat tttacataaa agataatctc tcaaggagtc ttatctgaaa
     1381 acgaaatata tagtccctct cgttttgtaa tatcgattgg ctttgttgaa tcggttacgt
     1441 accccggagc cggtcatatt ttcaggtaat acacacgctt tcagacattt cggctttcgt
     1501 catttttgta tcatgggcat agcttctgct acctgaccat cataatcacg cagcttcagt
     1561 gaagcagtga ccacctgttt aacccggtgt atcgttatga tcttatccag caattgaacc
     1621 gccccgggtt tcctggagag tgttttatct gtgaactcag gctgccagat catcgtttcc
     1681 gatggaagca taataagctt tttctgcttc tgccggtggg atatggccct gcctttccag
     1741 caatcgtcga ttgttatacc agtccaccca cgtgagtgtg gtcagctcat catactgaca
     1801 cgtgcattac ccctaccgcg ataatgcaac cgtacaatat agggcgtttc ctaaacgcag
     1861 ccctcatcac tccaatccaa caagacacag catttttgat cacgaagaaa gacaaataat
     1921 ttccgtaaat gtttccgttg ttacaaataa caacagtgtt ttacatttct ttggcctcag
     1981 gcccgcgcat gttgccattc gatgtcattt tcctgactcg tttcttcttt atggtgtagt
     2041 gtgatcttca ctttatggat gctaacaata tgaaaagaaa aattattccc gtgctaatcg
     2101 gttgtacgct ctctttctct gccctggcgg cacaacctac ggctgagcgc tatgtcgtca
     2161 gttttccaga aggcacgcac gtgaactacg ccggcgcatt tgccagtgca ttcccgaacg
     2221 gccttccggt tgggataggt tctggcctgc tgttcaccgg taaacagggc gatgccctga
     2281 cattcgcaac cattaccgat cgcggtccga acgcggattc accgaaagag gggaaaaacg
     2341 aaactaaaat tttcgttacg ccagatttcg cgccgctgct gatgacgatt cgtgtacaaa
     2401 acggcaaagc ggaggccatc gatccccgtc ctctgcatga cgataaaggc gcgatcaacg
     2461 gtctgccgct ggcaagcgac gtgattggct ccaccaatga agtggccttc agcgacacgt
     2521 tacatagact gaagggggat aatcgcgggc tggatacgga agggatcact ccggatggta
     2581 aaggaggtta ctggctgtgc gatgagtatg gcccgttcct gattaacatc gacagtaaag
     2641 ggaaaatcct ggcaatccac ggtccgcagg cggcggaagg ggaaaaagcg attgcgggcg
     2701 gtttgccaaa tatcctcaaa tggcgtcagg cgaaccgcgg ctttgaaggc ctcacccgta
     2761 tgccggacgg gcgtattatt gtcgccgtgc aaagtacgct ggatatcgac gctaagagca
     2821 agaaaaaggc gctgtttacg cgtctggtga gcttcgatcc ggcaagcgga aaaaccgcga
     2881 tgtacggtta tcctatcgac agcgcggcct acagcaaaag cagcgacgct aaaatcggag
     2941 acatcgtggc gctcgataac cagcacatcc tgctgatcga acagggaaga gataaaaaca
     3001 acagaatgcg taacctgatt tacgaggtcg atctcaataa ggcgagcgac ctgtcaggct
     3061 tcgacaagcc gggtgagtat ccggagtttg atgatgagaa aaccctgtca cagcgcggca
     3121 ttacccttgc gcagaaaacg caggttgttg atctgcgctc cttgggctgg cagcaggaga
     3181 aggctgaagg gttggcgctg atcgacagca aaacgctggc ggtggcgaac gataacgact
     3241 ttggcgtgaa ggtggcgatg caacatccgg tcgagggcaa gacattcaag gattatcggg
     3301 tgaacgcgga aggaaagctg acgcttgacg acaagcaggt tgaaacgacc ctcagagtga
     3361 agccactgga gaaaccggag tctgacagtg aactgtggat tgtgacgctg ccggaagcgt
     3421 tgaaataagt ttataaggta cggacagcag tatcgcttag tttttcaaat tcatgtatgt
     3481 gaacaatatt ggggtcccgg cgtagacccc caatgaaagc gtcaccacgt gaaaacatgc
     3541 ctgcacggtt tacacgtcat cccatggtgg cagccggtta actttcctgc gccaccagtg
     3601 gaaaaaggcc ataagcagtc cgaacaaaag taagcgtaca gcgagggccg tattgacggg
     3661 gatgtgttat tcagctggca gtgctatgcg ccacggaagc agttcgctga cccggttgac
     3721 cggccagtct gctatgacgc caagcacatg gcgaaggtag ctttctggat ccacgtcatt
     3781 cagtttgcac gtcccgatca ggctgtacag tagcgctccc cgctcaccac catggccaga
     3841 gccgaagaac agggtcttca tcttttcacg caaccagctt tccagggatt tcaacagcgg
     3901 tttcgttttt cgctgacgtt cagcaagccg ctgctctgcc ggcattcccc ttatatccgc
     3961 ctctatggcg tacaactgac cgatctgctc cagggcttct tccgtcagtg ctgacgggat
     4021 gcggacgtgc acatcgtgga tctttcggcg ggcatgagcc cagcaggcag cttccgttat
     4081 cccaccattg cgatacagct cgttgaaccc ggcgtacgca tccgcttgca gcacaccgct
     4141 gaagcaagca agatgagtct gcggatggat gccttttctg tccgggctgt aagcgaacca
     4201 cactgcaggt gccaacgctg acccggcatt gcggtcatca cgaacatacg cccacaaccg
     4261 cccggtcttc gtcttcttat tacccggcag cagtacctgg accggggtat catcggcatg
     4321 gagtttgccg tcagtcatga catagccatg aagcgcctct tccagcggag acagcagccg
     4381 gcagcatgca tccacccagc ccgacagcag tgaacggctc agctccacac cttgccggcc
     4441 gtatatttct gactggcaat acagcggggt gtgctctgca tacttcgagg tcagcacgcg
     4501 ggccagcagc cccggtccgg cgataccccg ctcgatgggc cgcgaaggtg caggtgcctg
     4561 cacgatgg
//
LOCUS       DADXDL010000182         4515 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.182, whole genome shotgun sequence.
ACCESSION   DADXDL010000182 DADXDL010000000
VERSION     DADXDL010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4515)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4515)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4515
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.182"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            170..1327
                     /gene="acrE"
                     /locus_tag="IRB70_004727"
     CDS             170..1327
                     /gene="acrE"
                     /locus_tag="IRB70_004727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter periplasmic
                     adaptor subunit AcrE"
                     /protein_id="HBC0634535.1"
                     /translation="MTKHARFFLLPSFILISAALIAGCNDKGEEKAHVGEPQVTVHIV
                     KTAPLEVKTELPGRTNAYRIAEVRPQVSGIVLSRNFTEGSDVQAGQSLYQIDPATYQA
                     SYDSAKGELAKSEAAAAIAHLTVKRYVPLVGTKYISQQEYDQAIADARQADAAVIAAK
                     ATVESARINLAYTKVTAPISGRIGKSTVTEGALVTNGQTTELATVQQLDPIYVDVTQS
                     SNDFMRLKQSVEQGNLHKENATSNVELVMENGQTYPLKGTLQFSDVTVDESTGSITLR
                     AVFPNPQHTLLPGMFVRARIDEGVQSDAILIPQQGVSRTPRGDATVLIVNDKSQVEAR
                     PVVASQAIGDKWLISEGLKSGDQVIVSGLQKARPGEQVKATTDTPADTASK"
     gene            1339..4443
                     /gene="acrF"
                     /locus_tag="IRB70_004728"
     CDS             1339..4443
                     /gene="acrF"
                     /locus_tag="IRB70_004728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux RND transporter permease
                     subunit AcrF"
                     /protein_id="HBC0634536.1"
                     /translation="MANFFIRRPIFAWVLAIILMMAGVLAILQLPVAQYPTIAPPAVS
                     VSANYPGADAQTVQDTVTQVIEQNMNGIDNLMYMSSTSDSAGSVTITLTFQSGTDPDI
                     AQVQVQNKLQLATPLLPQEVQQQGISVEKSSSSYLMVAGFVSDNPGTTQDDISDYVAS
                     NVKDTLSRLNGVGDVQLFGAQYAMRIWLDADLLNKYKLTPVDVINQLKVQNDQIAAGQ
                     LGGTPALPGQQLNASIIAQTRLKNPEEFGKVTLRVNSDGSVVRLKDVARVELGGENYN
                     VIARINGKPAAGLGIKLATGANALDTAKAIKAKLAELQPFFPQGMKVLYPYDTTPFVQ
                     LSIHEVVKTLFEAIMLVFLVMYLFLQNMRATLIPTIAVPVVLLGTFAILAAFGYSINT
                     LTMFGMVLAIGLLVDDAIVVVENVERVMMEDKLPPKEATEKSMSQIQGALVGIAMVLS
                     AVFIPMAFFGGSTGAIYRQFSITIVSAMALSVLVALILTPALCATLLKPVSAEHHENK
                     GGFFGWFNTTFDHSVNHYTNSVGKILGSTGRYLLIYALIVAGMVVLFLRLPSSFLPEE
                     DQGVFLTMIQLPAGATQERTQKVLDQVTDYYLKNEKANVESVFTVNGFSFSGQAQNAG
                     MAFVSLKPWEERSGDENSAEAVIHRAKMELGKIRDGFVIPFNMPAIVELGTATGFDFE
                     LIDQAGLGHDALTQARNQLLGMAAQHPASLVSVRPNGLEDTAQFKLEVDQEKAQALGV
                     SLSDINQTISTALGGTYVNDFIDRGRVKKVYVQADAKFRMLPEDVDKLYVRSANGEMV
                     PFSAFTSAHWVYGSPRLERYNGLPSMEIQGEAAPGTSSGDAMALMENLASQLPAGIGY
                     DWTGMSYQERLSGNQAPALVAISFVVVFLCLAALYESWSIPVSVMLVVPLGIVGVLLA
                     ATLFNQKNDVYFMVGLLTTIGLSAKNAILIVEFAKDLMEKEGKGVVEATLMAVRMRLR
                     PILMTSLAFILGVLPLAISNGAGSGAQNAVGIGVMGGMVSATLLAIFFVPVFFVVIRR
                     CFKG"
BASE COUNT         1094 a         1093 c         1190 g         1138 t
ORIGIN      
        1 atattaatct ttttttgtgt ttatgtgcct tgagacgcta gtattcataa ctattcctta
       61 catcgacgaa tgataatttg taggatagcg aactgtattt ttctttctgc gagttaacgc
      121 gttgcctttt tgggtaaata acgcgctttt ggttttttga ggaatagtaa tgacgaaaca
      181 tgccaggttt ttcctcctgc cctcctttat tctgatctcc gcggctttaa tcgccggttg
      241 taacgataag ggagaagaga aagctcacgt cggtgaaccg caggttaccg ttcatattgt
      301 gaaaacggcc ccgttagaag ttaagactga attaccaggc cgcaccaatg cttaccgtat
      361 agccgaagtt cgcccacagg ttagcgggat cgtactgagt cgcaatttca ctgaaggcag
      421 cgatgtgcaa gcaggccagt ctctgtacca gatcgatccc gcgacctatc aggcaagtta
      481 tgacagcgcg aaaggcgaac tggcgaaaag tgaagccgcc gccgccatcg cgcatttgac
      541 ggtaaaacgt tacgttccgc tcgtgggtac gaaatacatc agtcagcagg agtacgacca
      601 ggccattgct gatgctcgcc aggccgatgc cgccgtgatt gccgcaaaag ccacggtcga
      661 aagcgctcgc atcaatctcg cttataccaa agtgactgcg ccaattagtg gacgtatcgg
      721 caaatcgact gtgaccgaag gcgctcttgt cactaatggg caaacgactg aactggcgac
      781 tgtccagcag ctcgatccta tctacgttga tgtgacccaa tccagcaacg attttatgag
      841 gctgaagcaa tccgtagagc aaggaaattt gcataaggaa aacgccacca gcaacgtaga
      901 gttggtcatg gaaaacggtc aaacctatcc cctgaaaggt acgctgcaat tctccgatgt
      961 taccgttgat gaaagcaccg gctccataac cctacgtgcc gtcttcccta acccgcaaca
     1021 tacgctttta cctggtatgt ttgtgcgcgc acggattgat gaaggcgtcc aatctgatgc
     1081 cattcttatc ccgcaacaag gcgttagccg cacaccgcgt ggtgatgcaa ccgtgctgat
     1141 tgttaacgat aaaagtcagg ttgaagcgcg ccctgtcgtt gccagccagg cgattggcga
     1201 taaatggttg attagcgaag ggctgaaatc tggcgatcaa gtcattgtca gcggcctgca
     1261 aaaagcgcgt ccgggagagc aggttaaagc cactaccgat acccccgcag atactgcatc
     1321 gaagtaaggc aatctgacat ggcaaacttt tttattcgac gaccgatatt tgcatgggtg
     1381 ctggccatta ttctgatgat ggcgggtgta ctggcgatcc tacaattgcc cgtcgcccaa
     1441 tacccaacca ttgcgccgcc tgcagtttct gtttcggcaa actatccggg cgctgatgcg
     1501 cagaccgtgc aggatacggt gacgcaggtt atcgaacaga atatgaatgg tatcgataac
     1561 ctgatgtata tgtcctccac cagcgattcc gccggtagcg tgacaattac ccttaccttc
     1621 cagtccggga ccgatccaga tatcgcgcaa gtgcaggtgc agaacaaact ccagctcgcc
     1681 acgccgttgc tgccgcagga ggtacaacag caggggatca gtgttgaaaa gtccagtagc
     1741 agctatttga tggtggcggg ctttgtctct gataacccag gcaccacaca ggacgatatc
     1801 tcggactatg tggcctctaa cgttaaagat acgcttagcc gtctgaatgg cgtcggtgac
     1861 gtacaacttt tcggcgcaca gtatgcgatg cgtatctggt tggacgccga tctgctaaac
     1921 aaatacaaac tgacgccggt tgatgtgatt aaccagttga aggtacagaa cgatcagatc
     1981 gctgccggac agttgggcgg aacgccagcg ttaccagggc aacagttgaa cgcctcgatt
     2041 attgctcaga cgcggttaaa aaatccggaa gaattcggca aagtgacctt gcgcgtaaac
     2101 agtgacggct cggtggtacg cctgaaagat gtcgcacggg ttgaacttgg cggtgaaaac
     2161 tataacgtta tcgctcgcat caacggtaaa ccggcggcgg gcctgggtat taagctggca
     2221 accggcgcta atgctctcga taccgcgaaa gccattaagg caaaactggc ggaattacag
     2281 ccattcttcc cgcagggaat gaaggttctc tacccttatg acaccacgcc attcgtccag
     2341 ctttctattc acgaagtggt aaaaacgctg ttcgaagcca ttatgctggt gttcctggtg
     2401 atgtatctgt tcttgcagaa tatgcgagca acgctgatcc ccaccattgc ggtacccgta
     2461 gtgttgttag ggacgtttgc catcctcgcc gcttttggtt actccatcaa tacactaacg
     2521 atgttcggga tggtgcttgc catcgggctg ctcgtcgatg atgcgatagt ggtggtggag
     2581 aacgtcgagc gcgtgatgat ggaggataag ctcccgccaa aagaagcgac ggaaaaatca
     2641 atgtcgcaaa tccagggcgc actggtgggt atcgcgatgg tgctgtcagc ggtatttatt
     2701 ccaatggcat tcttcggcgg ttctactggg gcaatttacc gccagttctc tatcaccatc
     2761 gtttcggcaa tggcgctttc tgttctggtg gcattgattc ttaccccagc gttatgtgca
     2821 acactgctca aacccgtctc tgctgagcat cacgaaaata agggcggttt cttcggctgg
     2881 tttaatacca ccttcgatca tagcgttaac cactacacca acagcgtcgg caaaatcctc
     2941 ggttccacag gacgatattt actgatctat gcactaattg ttgctggaat ggtggtgttg
     3001 tttttacgtc ttccgtcttc cttcttacct gaagaggatc agggagtctt cctgactatg
     3061 attcagttac ccgctggcgc gacgcaagag cggacgcaaa aagtgttgga tcaagtgacg
     3121 gattactatc tgaagaacga gaaagcgaac gtagaaagtg tctttacggt taacggcttt
     3181 agcttcagcg gccaggcaca aaacgccggt atggctttcg tcagtctgaa accgtgggaa
     3241 gagcgtagtg gtgacgaaaa cagtgcggaa gcggtaatcc atcgtgccaa aatggagttg
     3301 ggcaagatcc gcgacggttt tgtcattcca ttcaatatgc cagccattgt tgaactgggc
     3361 acggcaacgg gtttcgactt tgagttaatt gatcaggctg ggctgggtca cgatgccctg
     3421 acccaggccc gtaaccagtt gcttggcatg gcggcgcaac atcctgccag cttagtcagc
     3481 gtgcgtccta atggtctgga agacaccgcg cagtttaaac tggaagttga ccaggaaaag
     3541 gcgcaggcat taggtgtttc actttctgac atcaatcaga ctatttcaac ggcgttgggt
     3601 gggacttacg ttaacgactt cattgaccgt ggtcgcgtga aaaaggtgta tgttcaggcg
     3661 gatgccaaat tccgtatgct gccagaagat gtcgataaac tttatgtccg cagcgccaac
     3721 ggcgaaatgg tgccattctc tgcctttacc tctgcacatt gggtgtatgg ctctccgcga
     3781 ctggagcgct acaacggtct gccgtcaatg gagattcagg gggaagccgc gccaggaacc
     3841 agttccggcg atgccatggc gttgatggaa aaccttgcat cacaattacc agctggcatt
     3901 ggttatgact ggacgggtat gtcatatcag gaacgcttat cgggaaacca ggctcccgct
     3961 ctggtagcaa tttcctttgt ggttgttttc ctgtgccttg ctgcactcta tgaaagctgg
     4021 tcaattcctg tctcggttat gttggtcgtg ccgttaggga ttgtcggcgt gctactagcg
     4081 gcgacactct ttaatcaaaa aaatgacgtc tactttatgg tgggcttgct aacgacaatt
     4141 ggcttgtcgg ctaaaaacgc tattttgatt gttgagttcg ctaaagatct catggaaaaa
     4201 gagggtaaag gtgttgttga agcgacacta atggcagtac gtatgcgtct gcgtcctatc
     4261 ctgatgacct ctctcgcctt tattctcggc gtattaccgc tagctatcag taacggtgcc
     4321 ggcagtggcg cgcagaacgc agtgggtatc ggggtaatgg gcgggatggt ttctgcaacg
     4381 ttgctggcaa tcttcttcgt gccggtgttc tttgtggtga tccgccgttg ctttaaagga
     4441 taaatcagaa acataaaggc actttcgggt gcctttatta ttttcagtga aacccataaa
     4501 aattaataag atatt
//
LOCUS       DADXDL010000183         4511 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.183, whole genome shotgun sequence.
ACCESSION   DADXDL010000183 DADXDL010000000
VERSION     DADXDL010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4511)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4511)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4511
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.183"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..209)
                     /gene="tuf"
                     /locus_tag="IRB70_004729"
     CDS             complement(<1..209)
                     /gene="tuf"
                     /locus_tag="IRB70_004729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="EF-Tu; promotes GTP-dependent binding of
                     aminoacyl-tRNA to the A-site of ribosomes during protein
                     biosynthesis; when the tRNA anticodon matches the mRNA
                     codon, GTP hydrolysis results; the inactive EF-Tu-GDP
                     leaves the ribosome and release of GDP is promoted by
                     elongation factor Ts; many prokaryotes have two copies of
                     the gene encoding EF-Tu; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBC0634537.1"
                     /translation="MSKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGGAA
                     RAFDQIDNAPEEKARGITINTSHVE"
     gene            complement(324..399)
                     /locus_tag="IRB70_004730"
     tRNA            complement(324..399)
                     /locus_tag="IRB70_004730"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(364..366),aa:Thr,seq:ggt)
     gene            complement(406..480)
                     /locus_tag="IRB70_004731"
     tRNA            complement(406..480)
                     /locus_tag="IRB70_004731"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(445..447),aa:Gly,seq:tcc)
     gene            complement(597..681)
                     /locus_tag="IRB70_004732"
     tRNA            complement(597..681)
                     /locus_tag="IRB70_004732"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(645..647),aa:Tyr,seq:gta)
     gene            complement(690..765)
                     /locus_tag="IRB70_004733"
     tRNA            complement(690..765)
                     /locus_tag="IRB70_004733"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(730..732),aa:Thr,seq:tgt)
     gene            1127..2077
                     /gene="coaA"
                     /locus_tag="IRB70_004734"
                     /gene_synonym="panK"
     CDS             1127..2077
                     /gene="coaA"
                     /locus_tag="IRB70_004734"
                     /gene_synonym="panK"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBC0634538.1"
                     /translation="MSIKEQTLMTPYLQFDRNQWAALRDSVPMTLSEDEIARLKGINE
                     DLSLEEVAEIYLPLSRLLNFYISSNLRRQAVLEQFLGTNGQRIPYIISIAGSVAVGKS
                     TTARVLQALLSRWPEHRRVELITTDGFLHPNQVLKERGLMKKKGFPESYDMHRLVKFV
                     SDLKSGVPNVTAPVYSHLIYDVIPDGDKTVVQPDILILEGLNVLQSGMDYPHDPHHVF
                     VSDFVDFSIYVDAPEDLLQTWYINRFLKFREGAFTDPDSYFHNYAKLTKEEAIKTAMT
                     LWKEINWLNLKQNILPTRERASLILTKSANHAVEEVRLRK"
     gene            complement(2106..3071)
                     /gene="birA"
                     /locus_tag="IRB70_004735"
     CDS             complement(2106..3071)
                     /gene="birA"
                     /locus_tag="IRB70_004735"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional biotin--[acetyl-CoA-carboxylase]
                     ligase/biotin operon repressor BirA"
                     /protein_id="HBC0634539.1"
                     /translation="MKDNTVPLKLIALLANGEFHSGEQLGETLGMSRAAINKHIQTLR
                     DWGVDVFTVPGKGYSLPEPIQLLNAEQILGQLDGGSVTVLPVIDSTNQYLLDRIGELK
                     SGDACVAEYQQAGRGRRGRKWFSPFGANLYLSMFWRLEQGPAAAIGLSLVIGIVMAEV
                     LRKLGADKVRVKWPNDLYLQDRKLAGILVELTGKTGDAAQIVIGAGINMAMRRVEESV
                     VNQGWITLQEAGINLDRNTLAAMLIRELRAALELFEQEGLAPYLSRWEKLDNFINRPV
                     KLIIGDKEIFGISRGIDKQGALLLEQDGIIKPWMGGEISLRSAEK"
     gene            complement(3068..4096)
                     /gene="murB"
                     /locus_tag="IRB70_004736"
     CDS             complement(3068..4096)
                     /gene="murB"
                     /locus_tag="IRB70_004736"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBC0634540.1"
                     /translation="MNHSLKPWNTFGIDHNAQHIVCAEDEQQLLNAWQHATAKGQSVL
                     ILGEGSNVLFLEDYRGTVIINRIKGIEIHDEPDAWYLHVGAGENWHRLVKYTLQEGMP
                     GLENLALIPGCVGSSPIQNIGAYGVELQRVCAYVDCVELATGKQVRLTAKECRFGYRD
                     SVFKHEYQDRFAIVAVGLRLPKEWQPVLTYGDLTRLDPTTVTPQQVFNAVCHMRTTKL
                     PDPKVNGNAGSFFKNPVVSAETAKALLAQFPTAPNYPQADGSVKLAAGWLIDQCQLKG
                     MQMGGAAVHRQQALVLINEDNAKSEDVVQLAHHVRQKVGEKFNVWLEPEVRFIGASGE
                     VSAVETIS"
     gene            complement(4233..4348)
                     /gene="rrf"
                     /locus_tag="IRB70_004737"
     rRNA            complement(4233..4348)
                     /gene="rrf"
                     /locus_tag="IRB70_004737"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         1150 a         1130 c         1011 g         1220 t
ORIGIN      
        1 tattcaacgt gagaagtgtt gatggtgata ccacgagctt tttcttccgg cgcgttatcg
       61 atctggtcga atgcgcgagc agcaccgccg taggttttag ccagtacggt agtgattgca
      121 gcggtcagcg ttgttttacc atggtcaacg tggccgatag taccgacgtt aacgtgcggt
      181 tttgtacgtt caaacttttc tttagacatc gattgtccct ctaagacacg gataaatcgg
      241 tgatatcacc acatcaacca ggcaacatgc ccgacttgtt gaatgcaata aacagaagga
      301 aaaaacaggg aggagaaaag aagtggtgct gataggcaga ttcgaactgc cgacctcacc
      361 cttaccaagg gtgcgctcta ccaactgagc tatatcagca catcttggag cgggcagcgg
      421 gaatcgaacc cgcatcatca gcttggaagg ctgaggtaat agccattata cgatgcccgc
      481 atcctggaac tcggctacct gattttcatt ctgcactgaa tatcgagaga agctctcttt
      541 attcgagccg gtaagcgaac ttatcgtctc gggctacgcc atcgcgtggc cgaaattggt
      601 ggtgggggaa ggattcgaac cttcgaagtc tgtgacggca gatttacagt ctgctccctt
      661 tggccgctcg ggaaccccac cggacttgat ggtgccgact accggaatcg aactggtgac
      721 ctactgatta caagtcagtt gctctaccta ctgagctaag tcggcatcaa gtagcgcgca
      781 ttctatggag acatgcgagt tcatgcaact aaaaaattgc ataatttgtt ttattggtca
      841 cattttatgc gacacgatga agaaacagcc gaatggaggg cagattagca cactttttca
      901 acatcattgt gctcaacaat gcgctcctgc taaaccataa ttctttttat cagatggaat
      961 atctgtcaca ttgcttttca acgatagctt cctgggagag attttttctt attattcctc
     1021 cccatctggt gttaccctcc tgcccattaa cccattcaac agaactgtga cgcgccatgg
     1081 caaatatcgc tttgccgata gagctatgac cgccagaaac atgcttatga gtataaaaga
     1141 gcaaacgtta atgacgcctt acctacagtt tgaccgcaac cagtgggcag ctctgcgtga
     1201 ttccgtacct atgacgttat cggaagatga gatcgcccgt ctcaaaggta ttaatgaaga
     1261 tctctcgtta gaagaagttg ccgagatcta tttacctctg tcacgtttgc tgaacttcta
     1321 tataagctcg aatctgcgcc gtcaggcagt tctggaacag tttcttggta ccaacgggca
     1381 acgcattcct tacattatca gtattgctgg tagtgtcgcg gtggggaaaa gtacaaccgc
     1441 ccgtgtattg caggcgctat taagccgttg gccggaacat cgtcgtgttg aactgatcac
     1501 tacagatggc ttccttcacc ctaatcaggt tctgaaagaa cgaggtctga tgaagaagaa
     1561 aggcttcccg gaatcgtatg atatgcatcg cctggtgaag tttgtttccg atctcaagtc
     1621 cggcgtgcca aacgttacag cccctgttta ctcgcatctt atttatgatg tgatcccgga
     1681 tggagataaa acggttgttc agcctgatat tttaattctt gaagggttaa atgtcttaca
     1741 gagcgggatg gattatccac acgatccaca tcatgtattt gtttctgatt ttgtcgattt
     1801 ttcgatatat gttgatgctc cggaagactt acttcagaca tggtatatca accgttttct
     1861 gaaattccgc gaaggggctt ttacagaccc ggattcctat tttcataact acgcgaaatt
     1921 aactaaagaa gaagctatta agactgccat gacgttgtgg aaagagatca actggctgaa
     1981 cttaaagcaa aatattctac ctactcgtga gcgcgccagt ttaatcctga cgaaaagtgc
     2041 taatcatgcg gtagaagagg tcagactacg caaataattt gcaggggagc taatgctccc
     2101 ctttcttatt tttctgcact acgcagggat atttcaccgc ccatccaggg ttttattatt
     2161 ccatcctgct caagcaataa agcgccctgt ttgtctattc cgcgtgaaat gccaaatatt
     2221 tctttatcac caatgataag tttcactggg cgattaataa aattatccag cttttcccag
     2281 cgcgaaagat aaggtgccaa tccttcttgt tcgaagagtt ccagcgccgc gcgtaattca
     2341 cgtattagca tggccgccaa cgtattacga tcgagattga tccccgcttc ctgcagcgtg
     2401 atccacccct gattaacgac actctcttca acacgacgca ttgccatgtt gatcccggct
     2461 ccaatgacta tttgcgccgc atcgccggtt ttaccagtca gctccacaag aatgcctgcc
     2521 agcttgcgat cctgcagata gaggtcatta ggccatttaa cacgaacttt atctgcaccc
     2581 agcttgcgta atacttccgc catcacgata ccgataacca gacttaaacc aatcgccgcc
     2641 gccgggcctt gttccagacg ccagaacatc gacaaatata agtttgcgcc aaaaggcgaa
     2701 aaccatttcc gaccccggcg accacggcca gcctgctggt attctgcaac acaggcatcg
     2761 cccgatttaa gctctccgat acgatcaaga aggtactgat tcgtggagtc aataacgggt
     2821 agcacagtta cactaccgcc atccagctga cccaatatct gttcagcatt aagtaactgg
     2881 ataggctcag gcaggctgta tcctttaccc ggaacggtaa agacatcaac gccccagtca
     2941 cgcagtgtct gaatgtgttt attaatagcc gcccggctca ttcctaacgt ttcacccaac
     3001 tgctcaccag agtgaaattc gccattcgct aacagcgcga ttaatttcag cggaacggta
     3061 ttatccttca tgaaatcgtc tccactgcgc taacttcacc tgatgcacca ataaagcgaa
     3121 cttcaggctc aagccagaca ttaaattttt cacccacttt ttgtcttaca tgatgtgcca
     3181 gttgcaccac atcttcgctt tttgcattgt cttcattaat gaggactaac gcctgttgac
     3241 ggtgcaccgc agccccaccc atttgcatcc cttttagctg gcactgatcg ataagccaac
     3301 ctgctgccag ttttactgaa ccatccgcct ggggataatt tggtgctgtt ggaaattgtg
     3361 ccagtaatgc tttagccgtt tcggcagata caacagggtt tttgaagaaa ctaccggcat
     3421 tgccattcac ttttggatca gggagtttgg tggtgcgcat atgacacacc gcattaaata
     3481 cttgctgtgg cgttacggtt gtaggatcca gacgagttaa gtcaccatac gttagtacag
     3541 gttgccactc ttttggcaga cgcagaccta cggctacaat ggcgaagcgg tcctggtatt
     3601 catgtttaaa aacactgtcg cgatagccaa aacggcactc tttggcagtt aagcgcactt
     3661 gcttgcctgt cgccagttca acacagtcaa cataagcgca aactcgctgt aattctacgc
     3721 cataagcacc aatattctgg ataggtgatg agccgacaca accaggaatt aatgccagat
     3781 tttccagacc aggcatacct tcctgcaaag tgtattttac caggcgatgc cagttttctc
     3841 cggctcctac atgtaaatac cacgcatcag gttcatcatg aatttcgata cctttgatcc
     3901 ggttgatgat caccgtaccg cgatagtctt ccagaaaaag tacattactt ccttcaccca
     3961 gaataagaac ggattgtcct tttgcggttg catgctgcca ggcattgagt agttgttgtt
     4021 cgtcttcggc acatacaatg tgctgagcat tatgatcaat gccaaatgtg ttccagggtt
     4081 ttaaggagtg gttcatagct gctttcctga tgcaaaaacg aggctagttt accgtatctg
     4141 tggggggatg gcttgtagtt atgacgacag ggagtgtttg tagaaacgca aaaaggccca
     4201 gtcttccgac tgggccttct gctaaatttg atgcctggca gttccctact ctcgcatggg
     4261 gagaccccac actaccatcg gcgctacggc gtttcacttc tgagttcggc atggggtcag
     4321 gtgggaccac cgcgctaagg ccgccaggca aattctgttt atcagaccgc ttctgcgttc
     4381 tgatttaatc tgtatcaggc tgaaaatctt ctctcatccg ccaaaacatc ttcggcgttg
     4441 taaggttaag cctcacggtt cattagtacc ggttagctca acgcatcgct gcgcttacac
     4501 acccggccta t
//
LOCUS       DADXDL010000184         4461 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.184, whole genome shotgun sequence.
ACCESSION   DADXDL010000184 DADXDL010000000
VERSION     DADXDL010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4461)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4461)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4461
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.184"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(105..326)
                     /locus_tag="IRB70_004738"
     CDS             complement(105..326)
                     /locus_tag="IRB70_004738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HBC0634541.1"
                     /translation="MKIITRGEAMRIHRQHPASRLFPFCTGKYRWHGSAEAYTGREVQ
                     DIPGVLAVFAERRKDSFGPYVRLMSVTLN"
     gene            complement(389..865)
                     /locus_tag="IRB70_004739"
     CDS             complement(389..865)
                     /locus_tag="IRB70_004739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HBC0634542.1"
                     /translation="MQQISFLPGAMTPGERSLIQRALKTLDRHLHEPGVAFTSTRAAR
                     EWLILNMAGLEREEFRVLYLNNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAA
                     VVLAHNHPSGEVTPSKADRLITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL"
     gene            complement(881..1360)
                     /locus_tag="IRB70_004740"
     CDS             complement(881..1360)
                     /locus_tag="IRB70_004740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBC0634543.1"
                     /translation="MKIVSQNTTALSSATAPGNNQPQLVATPVPDEQRISFWPQHFGL
                     IPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFNAMN
                     GNRAEMSPEAAGIAACLMAYSHHACRTENYAMTVHYYRLRDYALQHPEYDAIMRIID"
     gene            complement(1626..2444)
                     /locus_tag="IRB70_004741"
     CDS             complement(1626..2444)
                     /locus_tag="IRB70_004741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBC0634544.1"
                     /translation="MQLASRFGHVNQIRRERPLTREELMYHVPSIFGEDRHTSRSERY
                     AYIPTITVLENLQREGFQPFFACQTRVRDQSRREYTKHMLRLRRAGQITGQHVPEIIL
                     LNSHDGSSSYQMLPGYFRAICTNGLVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFD
                     RIEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTTDILTPRRREDYGKDLWS
                     TYQTIQENMLKGGISGRSARGKRIHTRAIHSIDTDIKLNRALWVMAETLLESLR"
     gene            complement(2534..2767)
                     /locus_tag="IRB70_004742"
     CDS             complement(2534..2767)
                     /locus_tag="IRB70_004742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HBC0634545.1"
                     /translation="MSDCHPVLLPEGPFSRKQAMAATTAYRNVLIEDDYGTHFLLVIR
                     NAEGQLRWRCWNFESDAGKQLNSYLASEGILRQ"
     gene            complement(2773..3450)
                     /locus_tag="IRB70_004743"
     CDS             complement(2773..3450)
                     /locus_tag="IRB70_004743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001097314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634546.1"
                     /translation="MNTRALFPLLFTVASFSASAGNWAVKNGWCQTMTEDGQALVMLK
                     NGTIGITGLMQGCPNGVQTLLGSRISINGNLIPTSQMCNQQTGFRAVEVEIGQAPEMV
                     KKAVHSIAERDVSVLQAFGVRMEFTRGDMLKVCPKFVTSLAGFSPKQTTTINKDSVLQ
                     AARQAYAREYDEETTETADFGSYEVKGNKVEFEVFNPEDRAYDKVTVTVGADGNATSA
                     SVEFIGK"
     gene            complement(3598..4278)
                     /locus_tag="IRB70_004744"
     CDS             complement(3598..4278)
                     /locus_tag="IRB70_004744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001278649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WYL domain-containing protein"
                     /protein_id="HBC0634547.1"
                     /translation="MSDNRSRHDRLAVRLSLIISRLMAGESLSLKTLSDEFGVTERTL
                     QRDFHQRLVHLDLEYRNGRYSLRRQSSPGAIPEMLSFIQNTGIARILPLRNGRLITCL
                     TDNQEPSPCLIWLPAPNITATFPECFSQLILAIRQCIHISLMTERWYPSLEPCRLIYY
                     SGSWYLIALQKGKLQVFPLADIKSVSLTSERFERRGHIHSLVAEERFISALPHFSFIH
                     KLINTFNL"
BASE COUNT         1056 a         1116 c         1211 g         1078 t
ORIGIN      
        1 gcgcagaccg gcttcggtaa aggtgtattc gttgatgagc aggacctcat ccacagcggc
       61 gtctgagctc agccagtcgt actcgttttc cgggtgacgg aacatcagtt cagggtgacg
      121 ctcatcagcc ggacatacgg accaaaactg tccttacggc gttctgcaaa cacggccagc
      181 acaccgggaa tatcctgcac ttcacgaccg gtatacgctt cagcactgcc gtgccagcgg
      241 tatttgccgg tacagaacgg aaaaagacgg gatgctggat gctgacggtg aatacgcatg
      301 gcttcgccac gggtgatgat tttcatagtg ggatacctct gaagacagaa gataaaagtg
      361 aaaacaggtg tgatgtggtt gtgacgggtt aaagcagacc atgttcggca aaggagaaaa
      421 cctggttgcc accgactatc agatggtccg gcacccggat atccaccagg cccagtgcct
      481 gtaccagacg ttcggtgata agccggtctg ccttactggg tgtgacttca ccggacgggt
      541 gattgtgcgc cagcaccaca gcagcggcat tgtggtacag ggcgcgttta atcacttccc
      601 ggggatggac ttccgtgcgg ttgatggtgc cggtgaagag ggtttcaccg gcaatcagct
      661 gattctggtt attcagatac agcacccgga attcttcacg ctccagtccc gccatgttca
      721 gaatcagcca ttcccgtgcc gcacgggtgg aggtgaaggc cacgccgggt tcatgaagat
      781 ggcggtccag ggttttcagg gcccgctgaa tgagactgcg ctcgccgggc gtcatcgctc
      841 cgggcagaaa ggaaatctgt tgcattgttc ctgccccctt tcagtcaatg atgcgcataa
      901 tggcgtcgta ttccggatgt tgcagggcgt aatcccgcag ccggtaataa tggaccgtca
      961 tggcataatt ctccgtacga caggcatgat gactgtatgc catcagacag gctgcaatgc
     1021 cggcggcttc cggactcatt tcagcgcggt taccgttcat ggcattgaac agtacccatg
     1081 tttcgtcatc atcgtcatcc ggttcggggg ccataaatgc gccaccgttg ttcagggtgt
     1141 acagattcca gatgcccccg cagtagtctt cgcacagacg gtccatccag ccgaagacac
     1201 ggggctccag ggtcacccac tgtggaatga ggccaaaatg ctgcggccag aagctgatac
     1261 gttgttcatc agggacggga gtagcaacca gttggggctg gttattccct ggtgctgtgg
     1321 ctgaagaaag agcagttgtg ttctgagaaa cgattttcat gagtgaaatc cttacaatgt
     1381 gtataaatga gaggaaataa aggccggggg ctgacaacat cacgttcatc actgaccgtg
     1441 agacccggca atatcaggga tgaatgatat tcggctgaaa ttccggacag ccgtacgcgt
     1501 aaccgttccg gtcacagacg gatggccaga agatgccatt gcctgtactc agtctgcaca
     1561 gactgagttc tccggggcgt cgggtgattc tggtgcctga atcacgcctt cagggacaga
     1621 ttgcatcagc gcaggctctc cagtagcgtt tctgccatca cccacaatgc gcgattgagc
     1681 ttaatgtcgg tgtcgatgct gtgaatggca cgggtgtgga tacgttttcc tctggcactg
     1741 cgaccggaaa ttccgccttt cagcatattc tcctggatgg tctgataagt actccacagg
     1801 tccttaccgt aatcctcccg gcgtcgtggc gtcagaatgt cggtagtggt gacgggctga
     1861 tgttcatcac cataacggta agtcagcgcc gcctgtgcca gcgcctggcg tgccggtggc
     1921 ggcaggacca gcgactgcat ggcatcacgc ttttcctcaa tccggtcaaa cacgcccacc
     1981 acttcgtaag caccttctat gaccctgtcc accacgtttc cccggtgtgg cacccggact
     2041 tctcccagcg actgaccgca gaccaggcca ttggtacaaa tggcacgaaa atatccgggt
     2101 aacatctggt agctggatga accgtcatgg gagttgagca gaataatttc aggcacatgc
     2161 tgaccggtta tctgtccggc ccgccgcaga cgcagcatat gtttggtata ttcccggcgg
     2221 ctctggtcgc gcacacgggt ctggcaggcg aagaacggct gaaagccttc ccgctgcaga
     2281 ttttccagga cggtgatggt gggaatgtac gcataccgtt cactgcggga ggtgtgccgg
     2341 tcttctccaa aaatactcgg gacgtggtac atcagttctt cgcgtgtcag tgggcgctcc
     2401 cgacggatct gatttacatg accaaaacga ctggctaatt gcatactttg ctccttatga
     2461 atgaattagc ggtataaacg aaaaggccgc gtctcccgga gaagacgcgg cctgatggat
     2521 gaaatgaaga cgtttattgc ctgagaattc cctcactggc gaggtacgaa tttagctgtt
     2581 ttccggcgtc agactcaaaa ttccagcacc gccagcgtag ctgcccttcg gcattgcgga
     2641 taaccagcag gaaatgcgtt ccatagtcat cttcaataag cacattgcgg taagctgttg
     2701 tggcagccat tgcctgtttg cgtgagaaag ggccttcggg caataaaaca gggtgacagt
     2761 ccgacatacc ggctattttc cgataaattc aacgctggca ctggtggcat taccgtcagc
     2821 accaaccgtg acggtcactt tgtcgtacgc acggtcttca ggattgaata cttcaaactc
     2881 aaccttattg ccttttactt cgtaagagcc aaaatcagcg gtttctgttg tttcctcgtc
     2941 atattcccgg gcgtatgcct gccgggcagc ctgcaggacg gagtctttat taatagtggt
     3001 cgtctgtttc ggggaaaaac cggcaagtga tgtgacaaat ttcggacaga ccttcagcat
     3061 atcaccgcgg gtgaattcca ttcgtacacc aaatgcctgt aaaacggaca catcacgctc
     3121 tgctatggag tgaacggctt ttttgaccat ttccggcgcc tgtccgattt ccacctcaac
     3181 agccctgaat cccgtctgct gattacacat ttgtgatgtg gggatcaggt taccgttaat
     3241 actgatacgg ctgcccagga gcgtctgtac gccattcggg catccctgca tcaggccggt
     3301 aataccaatc gtgccatttt tcagcattac cagcgcctga ccatcttccg tcatggtctg
     3361 acaccagccg tttttgacag cccagttgcc ggcggaggcg gagaatgatg ccacagtgaa
     3421 cagcagggga aaaagagctc tggtattcat gactgacctc tgaaatgaac gtacggtgtt
     3481 attgataatg atggaaggta tgcagtgact gttcagggaa tgacgtagcc gtatatttag
     3541 ttttctgttc aacatattgt ctccatacct gtcgggacgg ctttggcagg ccggcgatca
     3601 caggttaaag gtgttgataa gtttatggat gaaagagaaa tgtggcaggg cggagataaa
     3661 acgctcttca gcgaccagac tgtggatgtg gcctctccgt tcaaaccgtt ctgatgtcag
     3721 gctgactgat ttgatatctg ccagaggaaa gacctgcagt tttcccttct gtaacgcgat
     3781 cagataccag ctaccgctgt aataaatgag ccggcagggc tccagtgacg gataccatcg
     3841 ctcagtcatc agagagatgt ggatacactg tcttattgcc aggatgagtt gcgagaaaca
     3901 ctcggggaac gttgcagtga tattcggcgc cggtagccag ataaggcagg gagagggctc
     3961 ctggttgtcg gtaagacagg ttatcagtcg tccgttccgg agcggaagta tccgtgcgat
     4021 cccggtattc tgtataaaag aaagcatttc agggatcgca cctgggctgc tctgtcgtct
     4081 gaggctgtac ctgccatttc tgtactctaa atccaggtga accagacgct gatgaaaatc
     4141 gcgctgtaaa gtacgttctg taacgccaaa ttcatctgac agtgttttta gtgacagaga
     4201 ttctccggcc atcagtcggc tgataatgag tgataagcga accgccaggc gatcatgccg
     4261 ggaacgatta tcagacatag atgtgcactc cgtaagaaaa catcttttat ttcatgatgt
     4321 tattatgtct catggtgttg aaaggatgtg tcgtatctga ataatcagga ataaaatgca
     4381 gcagaaaaaa tattccttta attatctgat ttttaatgat gatttcataa aaagaagaat
     4441 actcattaat ccagcgacac a
//
LOCUS       DADXDL010000185         4452 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.185, whole genome shotgun sequence.
ACCESSION   DADXDL010000185 DADXDL010000000
VERSION     DADXDL010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4452)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4452)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4452
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.185"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..217
                     /locus_tag="IRB70_004745"
     CDS             <1..217
                     /locus_tag="IRB70_004745"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634548.1"
                     /translation="KKPVIQPKNKEKVIEKEIKKKPFYMVEHENRFKSKLHKTKNTIN
                     EKIINQNQLTDENDDGGDNDGGGRFRM"
     gene            complement(227..496)
                     /locus_tag="IRB70_004746"
     CDS             complement(227..496)
                     /locus_tag="IRB70_004746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001722510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid replication protein"
                     /protein_id="HBC0634549.1"
                     /translation="MKVKNRKRELTAKEYAEQYDISVRTVKRYFSQDREDYEKEAKQR
                     RLKAFVLRESGMKWADVGIALGTTKHGAIALYKRYQQIDAPIKEA"
     gene            complement(493..1326)
                     /locus_tag="IRB70_004747"
     CDS             complement(493..1326)
                     /locus_tag="IRB70_004747"
                     /inference="COORDINATES: protein motif:HMM:NF020291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBC0634550.1"
                     /translation="MYKIENNKDILKSQIPLKPYASNDLDFGLTIQNKNKALDMLYLQ
                     VNHPLYLHTMIFDLDKENCFYEFENAHLPIPSFITKSPESGRCHYGYMLNAPITSTEK
                     SRQKPIKFARALYYNMATRLGADLSYAGLITKNPYSPHWSPFWSGADLYELNDLADCF
                     DDLEEPKKRENTGLAFGRNVEMFDTIRQWAYKNVLKYKNESSFNDFQNELLLKCQMHN
                     AYLNANDLLPYNEIKATSKSIAKWCWSKFENEEFSKIQSNRAKKGKPKGKTRKFLEAI
                     K"
     gene            1624..1917
                     /locus_tag="IRB70_004748"
     CDS             1624..1917
                     /locus_tag="IRB70_004748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016241877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634551.1"
                     /translation="MQKPKRRLGFMVGKSNATLPDETTDAAIDEEVTNLFFESLLESA
                     KEAVEIHNGKRPAARRTLHKVNRTTKDTIERSEAGTDVFTASGSDDLFKKLKL"
     gene            2555..2815
                     /locus_tag="IRB70_004749"
     CDS             2555..2815
                     /locus_tag="IRB70_004749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000564493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634552.1"
                     /translation="MNENDIDQSLLELLARYFYYIDPNEENTAFLEANKDEQDLCYFV
                     AYRYIKENKTQDLIGALKDQKDEDYIKAMKDYVYGGGKYGYR"
     gene            2802..3173
                     /gene="mobC"
                     /locus_tag="IRB70_004750"
     CDS             2802..3173
                     /gene="mobC"
                     /locus_tag="IRB70_004750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000379199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBC0634553.1"
                     /translation="MDTDRKRGRIGLNHEVRRDISIQFRVNKAEFDYLKELVEASGLE
                     RGHYIRKEILNSEPIVKRKMPDFEQSLFKEIQHQGNNINQIAKKLNTNEDFKQSLAAE
                     ANFAIKQLMKRILKACEVYTV"
     gene            3170..>4452
                     /locus_tag="IRB70_004751"
     CDS             3170..>4452
                     /locus_tag="IRB70_004751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020231148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBC0634554.1"
                     /translation="MKGSVAKTGKSFKNRVDYILKDDHDFICSNMASDYNNVSDLTDE
                     FKIVSSFRQDIKKPVFHAFLSLPKNEHLTDEQWQEIAKDYLKEMNINIEKHQYICVRH
                     NDTDQDHIHIVANRVGLDGSVWLGQHSAFNTIAACERLEIKHGLTITQSLKGQKSDVS
                     APTKAEIEQALRTGEKPARIVLQNALQAAMVGKPDLETFIDRLQAVGIDPAFNVASTG
                     NVAGVSFGIKNNEKNIYFKGSQLGKKYSWNTIKGKVKYDKNRDDELVRRFAARKTDDE
                     NSIRRSLVEPNINDDRTIIRNDDDTIGIGQYSIKPDTTDTYEGKQLVRSNHNRFKLSE
                     KYNRPTSPKVRRTTQKATQILNRVKKQHNKEPIKTYNKNGLNSWRDKSDSGSIGRILD
                     HAETANAATHSFRLKSGSRFNSRATKIEEIRDKLG"
BASE COUNT         1555 a          786 c          814 g         1297 t
ORIGIN      
        1 aaaaaaacca gttattcagc caaagaataa agaaaaagtg attgaaaaag aaataaagaa
       61 aaaaccgttt tatatggttg agcatgaaaa tagatttaaa tctaaactac ataaaaccaa
      121 aaacactatc aatgaaaaaa tcattaatca aaatcagcta acagatgaaa atgatgacgg
      181 cggtgataat gatggaggcg gtaggtttag gatgtaaaaa gaggctttaa gcctctttta
      241 ttggtgcgtc tatttgttga taacgtttat aaagagctat agccccgtgt tttgtagttc
      301 caagagcaat accaacatct gcccatttca tcccgctttc acgtaataca aatgctttta
      361 atcttctttg ttttgcttct ttctcatagt cttcacgatc ttgagaaaaa tatcttttta
      421 ctgttctaac actaatatca tattgttcag catactcttt tgctgtaagt tctctttttc
      481 tatttttaac tttcatttta tcgcctccaa aaacttacga gttttgcctt ttggttttcc
      541 cttttttgct ctatttgatt gtatcttact aaactcctca ttttcaaatt tagaccaaca
      601 ccatttagca atgctttttg atgttgcttt tatttcattg tatggcagta aatcattagc
      661 atttaaatat gcattatgca tttgacactt taacaataac tcattttgaa aatcattaaa
      721 tgaactttca ttcttatatt ttagcacatt tttataagcc cactgtctta tggtgtcgaa
      781 catttcaaca ttacgcccaa aagcaagccc tgtattttct cgttttttgg gttcttctaa
      841 atcatcaaaa caatcagcta aatcatttag ctcatataaa tcagcacctg accagaacgg
      901 cgaccaatgc ggactgtatg ggtttttagt aatcagtccg gcataactga gatcagcacc
      961 aagacgagta gccatattgt aatataatgc tctggcaaac tttatgggct tctgtctgct
     1021 tttctctgtt gatgttatag gagcattaag catataacca taatggcaac gtccagattc
     1081 gggtgattta gttataaaag acgggatagg caaatgggca ttttcaaact cataaaagca
     1141 gttttctttg tctaaatcaa atatcattgt atgaagatat aagggatgat ttacttgtaa
     1201 ataaagcata tctaaggctt tattcttatt ttgaatagtc aaaccaaaat caagatcatt
     1261 tgatgcatac ggctttaaag gtatttgact ttttaatata tctttgttat tttctatctt
     1321 gtacatatag cagtatcctt tctgtaatgc cccgtttctt gttggtcgcc aaactttcca
     1381 agaaacgcgg gcttttcttt tatttataat ctcttacagt tttactatat caaaaaaagt
     1441 tgtcaataga tccttcaaaa aaagttgtta actgtgccat tagccatatc aggtattaga
     1501 cggagttttt ggaaaactac accacagcga agcacaggtc gaagactact gcagagtaag
     1561 tcacactgta acgtatacta aactctatgc aggatctggc tgtgctggat aggagaacat
     1621 gagatgcaga aaccaaagcg tagactcggt tttatggttg gtaagagcaa tgcaacattg
     1681 cctgatgaaa caactgatgc agctatcgat gaggaagtta ccaacctgtt ttttgagtct
     1741 ctgcttgagt cggcaaaaga agctgtcgaa atccacaacg ggaaacgccc tgcagctcgt
     1801 agaacgctgc ataaggtaaa caggaccact aaagacacga tagaacgctc agaagcaggt
     1861 acagacgttt tcacagcctc cggttctgat gacctgttca aaaaactgaa gctgtagggt
     1921 aggggagagc tggccatctt caccagtaga acaaaccgac ccggaacggt gagagaaggc
     1981 caaccctcga tgcagtatat actatactaa tatatactat agtctgttga ttttatgagc
     2041 atttcaaacc catagacgcc agcaacagca gaaaagcaag ttttctactg ttctgtcgcc
     2101 gccgatcaaa ccccatccct ttgcatctgg tgaaatctga ctaccaagag gtcacgaact
     2161 ttgtcagatt tcacgtagca gcagcatttt ttacgcaaag ctacctatta cgcacagcta
     2221 cccatcaaga caatatatta tttaccctat tttttatttg cattttattt gttgtgcagg
     2281 gtatttattt atgtagccgc tatattgaca aactttttag atcggttatt tatttaaata
     2341 aggttgagtt cagctttatt ttttagcttt tcggaaactg aggcaaggtg taatcccgta
     2401 gccggtatta tacccaatcc ttcggattgc cctatctcgc tttgctcgta gggttgaaaa
     2461 agatctaccc ttccgcctat tccccttatc aaaggggagg cggtaaacca tagttttaca
     2521 ttgaatatta taaatatata taggagtgtt taaaatgaat gagaatgata tagatcagtc
     2581 cttgctagaa ctattagcaa gatattttta ttatatagac ccaaatgaag aaaatacagc
     2641 atttcttgaa gcaaataaag atgaacaaga tttatgttat tttgtagctt atcgctatat
     2701 taaagaaaat aaaactcaag atcttattgg tgctttgaaa gatcaaaaag atgaagatta
     2761 tatcaaagca atgaaagatt atgtttatgg aggtggtaaa tatggataca gatagaaaaa
     2821 gagggcgtat aggattaaat cacgaagtac gtagagatat atctatacag tttagagtaa
     2881 acaaagcaga gtttgattat ttaaaagagc ttgtggaagc atcagggctt gaaagaggtc
     2941 attacatccg aaaggagatt ttaaactctg aacctattgt taaaagaaaa atgccggatt
     3001 ttgaacaatc cttgtttaag gaaatacaac atcaaggtaa taatataaat cagattgcta
     3061 aaaaactaaa taccaacgaa gactttaaac aatctttagc cgcagaagct aactttgcca
     3121 taaagcaact tatgaaaaga atattaaaag cttgcgaggt ttatacagta tgaaaggaag
     3181 cgtagctaag acgggtaagt cttttaaaaa tagagttgat tacattctta aagatgacca
     3241 cgattttata tgtagcaata tggcaagtga ttataataat gttagtgatt taactgatga
     3301 gtttaaaatt gtaagtagct ttagacaaga tataaaaaaa ccagtttttc atgctttttt
     3361 atctcttccc aagaatgaac atttaacaga tgaacaatgg caagagatag caaaagacta
     3421 tttgaaagaa atgaatatta atatagaaaa acatcaatat atttgtgtgc gtcataacga
     3481 tacagatcaa gaccatatcc atatagtagc aaatagagtc ggtttagacg gttcagtatg
     3541 gcttgggcag cactcagcat ttaacacaat agcagcttgt gaacgtttgg agataaagca
     3601 cggcttaact attacacaaa gccttaaagg acaaaaatca gacgtatcag caccaaccaa
     3661 agcagagatc gagcaagcct tgaggacagg tgagaaacca gctcgtatcg tgctacagaa
     3721 cgcactacaa gcagctatgg taggaaaacc agaccttgag acattcatag acagactgca
     3781 ggctgtaggc atcgatccgg ccttcaacgt tgcaagcact ggcaacgtcg ccggagtgtc
     3841 gtttggtatc aaaaataatg aaaaaaatat ttattttaaa ggctcacagt taggtaaaaa
     3901 atacagttgg aacactatta aaggcaaggt gaaatatgac aaaaatagag atgatgaact
     3961 cgttagaaga ttcgcagcaa gaaaaacaga tgacgaaaat agtattagac gatcacttgt
     4021 tgaaccaaat atcaatgacg atagaaccat tatcagaaac gatgatgata ctatcggaat
     4081 cggtcagtac agcattaaac cagacacaac agacacttac gagggtaaac aactcgttag
     4141 aagcaaccac aaccgcttta aactcagcga aaaatacaat agaccaacaa gcccaaaagt
     4201 tagaagaaca acacagaaag ctacacaaat actcaacaga gttaaaaaac aacacaataa
     4261 agaaccaatc aaaacttata ataaaaatgg cctcaatagt tggcgtgata aatctgatag
     4321 cggttctatt ggtaggatac ttgatcatgc agaaacagca aacgcagcca cccattcatt
     4381 tagactcaag agcggtagcc gtttcaatag tagagcaact aagatcgaag agataagaga
     4441 taaacttgga at
//
LOCUS       DADXDL010000186         4448 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.186, whole genome shotgun sequence.
ACCESSION   DADXDL010000186 DADXDL010000000
VERSION     DADXDL010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4448)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4448)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4448
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.186"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..68)
                     /locus_tag="IRB70_004752"
     CDS             complement(<1..68)
                     /locus_tag="IRB70_004752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001575626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysis protein"
                     /protein_id="HBC0634555.1"
                     /translation="MSRVAAIIYTLVICTIVCLSWAV"
     gene            complement(65..598)
                     /locus_tag="IRB70_004753"
     CDS             complement(65..598)
                     /locus_tag="IRB70_004753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706619.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HBC0634556.1"
                     /translation="MSAKIKYGLSAAVLALIAAGASAPQILDQFLDEKEGNHTTAYRD
                     GSGLWTICRGATMVDGKPVIPGMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQK
                     AGIASFYPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGHDCRIRSNNCYGQ
                     VIRRDQESALACWGIDQ"
     gene            complement(654..968)
                     /locus_tag="IRB70_004754"
     CDS             complement(654..968)
                     /locus_tag="IRB70_004754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1327 domain-containing protein"
                     /protein_id="HBC0634557.1"
                     /translation="MTQNYKLIVKGIRNFENKVTVTLALRDKKRFDGEIFDLDISLDR
                     VEGAALEFYEAAARRSIRQVFLDVAAGLCEGDELLPETRPCSEARYTIKINSSDNSIT
                     GC"
     gene            complement(973..1188)
                     /locus_tag="IRB70_004755"
     CDS             complement(973..1188)
                     /locus_tag="IRB70_004755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II holin family protein"
                     /protein_id="HBC0634558.1"
                     /translation="MYQMEKITTGVSYTTSAVGTGYWFLQLLDRVSPSQWAAIGVLGS
                     LLFGLLTYLTNLYFKIREDRRKAARGE"
     gene            complement(1338..3191)
                     /locus_tag="IRB70_004756"
     CDS             complement(1338..3191)
                     /locus_tag="IRB70_004756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1737 domain-containing protein"
                     /protein_id="HBC0634559.1"
                     /translation="MAFKHYDVVRAASPSDLAEKLTHKLKEGWQPFGSPVAITPYTLM
                     QAIAAEGDVVVSGATEPEWYYVIVLAGQSNAMAYGEGLPLPDSYDAPHPRIKQLARRN
                     TVTPGGEVCVFNDIIPADHCLHDVQDMSTINHPRADLSKGQYGCVGQGLHIAKKLLPY
                     IPNNAGILLVPCCRGGSAFTQGTEGTFSESTGASQDSARWGVGKPLYQDLLFRTKAAL
                     QKNPKNVLLAICWMQGEFDMTNASYAQQPAAFLAMVQQFRADLAGLAAQCHGGSPASV
                     PWICGDTTYAWKQEHGTQYEVVYGAYKGKESQQIYFVPFMTDGSGVNTPTNNPSEDPD
                     IVGSGYYGSASRTNKNWVSSNRPTHFSSWARRGIIPDRMATAILNAAGRTSAFISGKA
                     PEIKPSPGGDTPSGPSADTSVRTISLLPTAGEAAAQGWSIKNGGIQLSDGVFKITKQS
                     NKAWSLTRPVDDAVSLLTRGGRLSCKFRLSGALTNNQFGLGIYLYTDVALPDVVAMTG
                     TGNPFLMSFFTQTTDGKLNLMHHKKAGNTKLGEFGNYSNDWQTLELVFTAGSATVTPK
                     LNGVAGPAFQVIKDSLTVGLNALTLTDITKNATYGVEIESLVLEINAPASS"
     gene            3452..3787
                     /gene="iraM"
                     /locus_tag="IRB70_004757"
     CDS             3452..3787
                     /gene="iraM"
                     /locus_tag="IRB70_004757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anti-adapter protein IraM"
                     /protein_id="HBC0634560.1"
                     /translation="MKWIVIDTVIQPSCGISFSVIWSKIKLIIWYQSDAFLPPESIFT
                     LTHTGIMLNNKVLPVTIYNVVPFNKTFWNLIKNSQECPTNTDNVLNECFNNRCTLQIC
                     PYGLKQQSP"
     gene            complement(4068..4199)
                     /locus_tag="IRB70_004758"
     CDS             complement(4068..4199)
                     /locus_tag="IRB70_004758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 family protein"
                     /protein_id="HBC0634561.1"
                     /translation="MIAYCFCEWHCSSRIMSVLADGVLVAGVVVAAFPLLKKKTPDC"
BASE COUNT         1174 a         1218 c          953 g         1103 t
ORIGIN      
        1 accgcccacg acaggcagac gatggtgcag ataaccagag tataaataat cgctgcgact
       61 ctgctcactg atctatcccc caacaggcta atgcgctttc ctggtcacga cgaataacct
      121 gtccatagca gttatttgaa cgtatgcggc aatcgtgccc accatctttt atccaccagc
      181 gaatcgcctc gcatgcgccc ttacgatcac cggcattcag ccgcttataa aacgtcgacg
      241 ggaaacactt accggggcca atgttatagg gatagaatga cgctataccc gctttctgtg
      301 gttcggtcag tggtacttta atattgcgct ccacccatgc cagcgcctta tcacgttcaa
      361 tagcgttaac ctggtcgcat ttttccttcg acagcttcat tcccggtatg acgggcttac
      421 catccaccat tgtggcacca cgacagatgg tccataaacc ggaaccatcg cggtatgccg
      481 tagtgtggtt accctctttt tcatccagaa actggtcaag tatttgagga gcagacgcgc
      541 ctgcagcaat cagcgccaga acagcagctg acaggccgta tttgattttt gcgctcatgg
      601 atatttatca ggatgctacc aatgaaagat accggaaagc caactgcaaa aagctaacaa
      661 cccgtaatcg agttatcaga actgttaatt tttatggtat accgcgcctc tgaacagggg
      721 cgcgtttctg gcaacagctc gtccccttca cataacccgg cagcaacatc caggaagacc
      781 tgtctgatgc tccttctggc tgctgcctca taaaactcca gcgcggcacc ttcaacacgg
      841 tccagcgaga tgtccaggtc aaaaatttca ccgtcaaagc gttttttgtc ccgtaacgct
      901 aaagttaccg taactttatt ctcaaaattg cggatccctt tcacaatcag tttatagttt
      961 tgagtcattg aattactctc cccgtgcagc cttacgacgg tcctctctga ttttgaaata
     1021 caggttagtc agatatgtca gcagcccaaa cagcagactc cccagcacgc ctattgccgc
     1081 ccactgagac ggggaaaccc tgtccagcaa ctgcaggaac cagtagcccg ttcccaccgc
     1141 tgacgtggtg tatgacacac ctgttgtgat tttttccatc tggtacatac cccgtctccc
     1201 gttatccgga agctgacaac aataaaaaag ccaccagtta agtactgatg gctctgataa
     1261 ctcatgcagg cgtctcagac gacccactga cactaccggt gagtttaacg ataccttcca
     1321 tttgactggc tcacttttta tgatgatgcc ggtgcattta tctccagcac cagactttct
     1381 atctcaacgc catacgttgc atttttggta atatccgtca gcgtcagtgc atttagtccc
     1441 actgtcagac tgtcttttat gacctggaat gccgggccag ccactccatt cagtttcgga
     1501 gtaaccgtgg cactgccggc ggtgaacacc agctccagcg tctgccagtc gttactgtaa
     1561 ttcccgaact cgcccaactt tgtgtttccg gctttcttgt gatgcatcag attcagtttg
     1621 ccgtctgtgg tctgggtgaa gaacgacatc aggaacgggt taccagtccc ggtcatcgcc
     1681 acgacgtcag gtaacgctac atcggtatac agataaattc ccagaccgaa ctggttgttg
     1741 gtcagtgcgc ctgacagtcg aaacttacag ctcagtctgc caccccgtgt cagcagggag
     1801 actgcgtcat ccaccgggcg cgtcagggac caggctttat tgctctgctt ggtgatctta
     1861 aatacaccat ctgacaactg aattccgcca ttcttaatgc tccagccctg cgcagcagcc
     1921 tctccggctg tcggcagcag ggagattgtg cgaacggacg tatctgcaga cggacccgat
     1981 ggcgtgtcgc cgccgggcga gggtttgatt tccggtgcct taccactgat gaaggctgag
     2041 gtgcgcccgg ctgcgttcag aatagcggtt gccatacgat cgggaataat gccacgacgc
     2101 gcccatgagc tgaaatgcgt cgggcgattt gatgataccc agtttttgtt cgttcgggat
     2161 gccgaaccgt aataaccaga cccgacaata tcaggatctt ctgacgggtt gtttgtcggt
     2221 gtattaactc cgctaccatc ggtcataaag ggaacaaaat aaatctgctg ggattcttta
     2281 cctttatatg caccatatac cacttcatat tgcgtaccgt gttcttgttt ccacgcgtat
     2341 gtcgtgtcgc cacaaatcca ggggactgat gccggacttc caccgtgaca ctgcgccgcc
     2401 agcccggcaa ggtcagcacg gaactgctgt accattgcaa gaaatgctgc tggctgctgg
     2461 gcgtaactgg cattcgtcat atcgaattcc ccctgcatcc agcatatcgc cagcaaaacg
     2521 tttttcgggt ttttctgcaa tgctgccttc gtgcggaaaa gcagatcctg atataacggc
     2581 ttacccactc cccagcgagc cgaatcctga ctggcccccg tggactcgct gaatgtcccc
     2641 tccgtgccct gggtgaatgc cgaaccacca cgacagcatg gtaccagcag gatccccgcg
     2701 ttattaggga tatacggaag cagttttttg gcaatatgta agccctgtcc gacacagccg
     2761 tactgccctt tgctcaggtc agcccgggga tggttaatcg tactcatatc ctgaacatca
     2821 tgcagacaat ggtcagcagg aatgatgtcg ttaaatacgc atacttcacc accgggagtc
     2881 actgtgttac gacgggccag ttgcttaatg cgcggatggg gcgcatcgta tgaatccgga
     2941 agcggaagcc cttcaccgta agccatggca ttggactgcc cggccagtac gatgacgtag
     3001 taccactccg gctcagttgc accactgacg accacatcac cttctgctgc aatcgcctgc
     3061 atcagggtat aaggggttat ggccaccgga ctaccaaacg gctgccagcc ctctttcagt
     3121 ttatgtgtca gcttttccgc aagatctgac ggcgacgccg ccctgacaac atcatagtgt
     3181 ttaaatgcca tggttctttc caccatctga aaaatgattc tttaaaatac ctgacatgta
     3241 atacagaaaa aacacaaaac cataccttaa ttaaaaacct catcatcaag cagatatgca
     3301 tggataaact acaagacgag atataaacca ccctgcattt aaataaacaa taaacaacat
     3361 cagaaaaata attctgctct atggtttaca atcaaaaata tcatttatac ttttcagaac
     3421 atcaccagca aggcataaac aaggaaacta aatgaagtgg attgtgattg atacagttat
     3481 ccagccatca tgcggaatat ctttttcagt catatggagt aaaataaaat taataatctg
     3541 gtatcaatcg gatgctttct tacctcctga aagtatattt acactgactc acacaggcat
     3601 catgctcaat aacaaagtgc tgcctgtaac catttacaac gtagtaccat tcaataaaac
     3661 attctggaat ttaatcaaaa acagccagga atgccctaca aatacagata acgtattgaa
     3721 tgaatgcttt aataaccgtt gcactctgca aatatgtcct tatgggctaa aacaacaaag
     3781 tccataagga gtttactcac atctgacaaa atcaatataa acagcccctc cggagagggg
     3841 ctggagagtg gcgctatgtg ccattgcatg gtgccgggtg cctcccggtg aattcagtac
     3901 cagcacctga atccgcgatt atcccatata cctactcgct gattgcccct ccgcacaggg
     3961 ggattcacca tgccagtttc ttttaacaaa ctccccgcaa accagacaac agtcaaccgc
     4021 ctgaattgtg aagtatttaa aaatttctcc cgctaactga tacccggcta acagtctggc
     4081 gttttctttt tcagcaacgg gaaagcagca accaccacac ccgccaccag cacaccgtca
     4141 gccagcactg acattatccg gctgctgcaa tgccattcac aaaaacagta agcaatcact
     4201 ttttaccgta accggtgata atccagatat gtatctaccc cagatgagta atccgaagtt
     4261 catccatacc acaggtcctg gctattctgt tgtactcctg aacaagagca aataattctg
     4321 aattagccac catgaactca tcgcaaaccc tctgtatagc atcactattc agaataataa
     4381 cgtctcttcc cgaaagacga tcaggagtac agaacaaaac tgtcaaacgg ctgaaggcct
     4441 ttgctcgt
//
LOCUS       DADXDL010000187         4406 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.187, whole genome shotgun sequence.
ACCESSION   DADXDL010000187 DADXDL010000000
VERSION     DADXDL010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4406
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.187"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..255)
                     /locus_tag="IRB70_004759"
     CDS             complement(<1..255)
                     /locus_tag="IRB70_004759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634562.1"
                     /translation="MSGKPAARQGDMTQYGGSIVQGSAGVRIGAPTGVACSVCPGGVT
                     SGHPVNPLLGAKVLPGETDIALPGPLPFILSRTYSSYRTKT"
     gene            484..1092
                     /locus_tag="IRB70_004760"
     CDS             484..1092
                     /locus_tag="IRB70_004760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione S-transferase"
                     /protein_id="HBC0634563.1"
                     /translation="MKLVGSYTSPFVRKLSILLLEKGITFEFINELPYNADNGVAQFN
                     PLGKVPVLVTEEGECWFDSAIIAEYIELMNVAPAMLPRDPLESLRVRKIEALADGIMD
                     AGLVSVREQARPAAQQSEDELLRQREKINRSLDVLEGYLVDGTLKTDTVNLATIAIAC
                     AVGYLNFRRVAPGWCVDRPHLVKLVENLFSRESFARTEPPKA"
     gene            1190..2581
                     /gene="selA"
                     /locus_tag="IRB70_004761"
     CDS             1190..2581
                     /gene="selA"
                     /locus_tag="IRB70_004761"
                     /EC_number="2.9.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-seryl-tRNA(Sec) selenium transferase"
                     /protein_id="HBC0634564.1"
                     /translation="MTTETRSLYSQLPAIDRLLRDSSFLSLRDTYGHTRVVELLRQML
                     DEAREVIRDSQTLPAWCENWAQEVDARLTKEAQSALRPVINLTGTVLHTNLGRALQAE
                     AAVEAVTKAMRSPVTLEYDLDDAGRGHRDRALAQLLCRITGAEDACIVNNNAAAVLLM
                     LAATASGKEVVVSRGELVEIGGAFRIPDVMRQAGCTLHEVGTTNRTHANDYRQAVNEN
                     TALLMKVHTSNYSIQGFTKAIDEAELVALGKELDVPVVTDLGSGSLVDLSQYGLPKEP
                     MPQELIAAGVSLVSFSGDKLLGGPQAGIIVGKKEMIARLQSHPLKRALRADKMTLAAL
                     EATLRLYLHPEALSKKLPTLRLLTRSAEVIQIQAQRLQAPLAAHYGAEFAVQVMPCLS
                     QIGSGSLPVDRLPSAALTFTPHDGRGSHLESLAARWRELPVPVIGRIYDGRLWLDLRC
                     LEDEQRFLEMLLK"
     gene            2578..>4406
                     /gene="selB"
                     /locus_tag="IRB70_004762"
     CDS             2578..>4406
                     /gene="selB"
                     /locus_tag="IRB70_004762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418047.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="selenocysteine-specific translation elongation
                     factor"
                     /protein_id="HBC0634565.1"
                     /translation="MIIATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAY
                     WPQPDGRVPGFIDVPGHEKFLSNMLAGVGGIDHALLVVACDDGVMAQTREHLAILQLT
                     GNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFITAATEGRGIDALREH
                     LLQLPEREHASQHSFRLAIDRAFTVKGAGLVVTGTALSGEVKVGDSIWLTGVNKPMRV
                     RALHAQNQPTETAHAGQRIALNIAGDAEKEQINRGDWLLADVPPEPFTRVIVELQTHT
                     PLTQWQPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRIVLRDISARNTLAG
                     ARVVMLNPPRRGKRKPEYLQWLASLARAQSDADALSVHLERGAVNLADFAWARQLNGE
                     GMRELLQQPGYIQAGYSLLNAPVAARWQRKILDTLATYHEKHRDEPGPGRERLRRMAL
                     PMEDEALVLLLIEKMRESGDILSHHGWLHLPDHKAGFSEEQQAIWQKAEPLFGDEPWW
                     VRDLAKETGTDEQAMRLTLRQAAQQGIITAIVKDRYYRNDRIVEFANMIRDLDQECGS
                     TCAADFRDRLGVGRKLAIQILEYFDRIGFTRRRGNDHLLRDAL"
BASE COUNT          983 a         1123 c         1310 g          990 t
ORIGIN      
        1 cgtttttgtc cggtaactgc tgtaggtgcg ggagagaatg aacggcagcg ggccgggcag
       61 ggcgatgtct gtctcgccgg gaaggacctt tgcaccgagc agcggattga ccggatggcc
      121 ggacgttact ccgccggggc acaccgaaca ggccacgccg gtgggggcac caatacgtac
      181 cccggctgaa ccctggacaa tgctaccgcc atactgcgtc atgtcgccct gacgcgccgc
      241 cggttttccg ctcatctgct catccttgtt ttatcgggtt atttgtctgc tgacaggcga
      301 aaccctacag atttataaga aagccttaag tgagatatct gtcagataag aacaattagg
      361 aaaatattta tatcaccatg ataaatatgt gatttattgg gaagtaacaa accatcaaca
      421 ttttctgccc tttttcccat caccaggcca tactgatatt tttcctcgca caaaggactc
      481 ggcatgaaac tcgtcggtag ctacaccagc ccgtttgtac gcaaactttc tattctgttg
      541 ttagaaaagg gcataacttt cgaatttatt aatgaactgc cctataacgc ggacaacggc
      601 gtggcgcaat ttaacccgtt agggaaagtg ccggtgctgg tgaccgaaga gggtgaatgt
      661 tggtttgatt cggcgatcat cgctgaatat attgaattaa tgaatgtcgc tccggcgatg
      721 ttgccgcgcg atccgctgga gtcgttgcga gtgcgcaaaa ttgaggcact ggcggatggc
      781 attatggatg ccgggctggt atcggtgcgt gaacaggcgc gtccggcggc gcagcagtct
      841 gaagatgaat tgttacgcca gcgggagaaa atcaaccgca gtctggatgt gctggaagga
      901 tatctggtcg atggcacgct caaaaccgat acggtcaatc tggcgactat cgccattgcc
      961 tgtgccgtcg gatatctcaa tttccgccgc gttgcgccag gctggtgtgt cgaccgccca
     1021 cacttagtca aactggtcga aaacctgttt agccgcgaaa gttttgctcg caccgaaccg
     1081 ccaaaggctt gatgcgcgat atgtcctcct gacccatctc acgttacaat ccgtggttat
     1141 gttaaacgcc cttctccgtg tgagagggcc ttgatcagcc aggtttccta tgacaaccga
     1201 aacgcgttcc ctctatagtc aacttccggc tattgatcgc ttattgcgcg atagctcctt
     1261 cctttctttg cgtgatactt atggtcacac ccgcgtggtg gaattgctgc gtcagatgct
     1321 tgacgaagcg cgagaagtga ttcgagacag ccagacgctt cccgcgtggt gtgaaaactg
     1381 ggcgcaagaa gtcgatgccc ggttgacgaa agaggcgcaa agcgcgctgc gtccggtaat
     1441 caacctgacg ggaaccgtgc tgcataccaa ccttgggcga gctttacagg cggaagccgc
     1501 ggtggaagcc gttacgaagg ctatgcgttc gccagtgacc ctcgagtacg atctggacga
     1561 cgccggacgc ggacatcgcg atcgggcgct ggcgcagctg ctgtgccgta ttacgggggc
     1621 ggaagatgcc tgtatcgtta ataacaatgc ggcggcggtg ttattgatgt tggcggccac
     1681 tgccagcggg aaagaggtgg tggtttctcg cggcgaactg gtggagattg gcggcgcgtt
     1741 tcgtattccc gatgttatgc gtcaggcagg ctgcacccta cacgaagtgg ggaccaccaa
     1801 ccgcacgcac gctaatgatt atcgccaggc ggtgaatgaa aataccgcgc tgttgatgaa
     1861 agtacatacc agtaactaca gcattcaggg attcaccaaa gcgatagatg aagcggaact
     1921 ggtggcgctc ggcaaagagc tggatgtccc cgtagtgact gatttaggca gtggctcgct
     1981 ggtcgatctt agccagtacg gtttgccgaa agagccaatg ccgcaggagt tgattgcggc
     2041 gggcgtcagt ctggtgagct tctccggcga caagttgtta ggcgggccgc aggcaggaat
     2101 tattgttggt aaaaaagaga tgatcgcccg actgcaaagc cacccgctga agcgtgcatt
     2161 acgcgcggat aaaatgaccc ttgcggcgct ggaagccacg ttgcgtcttt atttacaccc
     2221 tgaagctctg agtaaaaaat taccgaccct gcgcctgctt acccgcagcg cagaggtcat
     2281 tcaaatccag gcacaacgtt tacaggctcc ccttgccgca cattacggcg cggagtttgc
     2341 ggtacaggtt atgccatgtc tttcgcagat tggcagtggt tcgctgccgg ttgatcgcct
     2401 gccgagcgcg gcattaacgt ttacacccca tgatggacgc ggtagccacc ttgagtcatt
     2461 agccgcccgc tggcgtgaat tgccagtgcc ggtgattggt cgtatttatg acggacgatt
     2521 gtggctggat ttacgctgcc ttgaagatga gcaacggttt ttggagatgt tgttgaaatg
     2581 attattgcga ctgccggaca cgttgaccac ggcaaaacaa ccttattgca ggcgattact
     2641 ggcgtaaatg ccgaccgtct gccggaagaa aaaaagcgcg gcatgaccat cgatctcggc
     2701 tatgcctact ggccgcagcc ggatggtcgt gttccgggtt ttatcgacgt tcccggtcat
     2761 gaaaagtttc tttccaacat gctggcgggc gttggtggta tcgatcacgc gctgttggtg
     2821 gtggcgtgcg atgacggcgt gatggcacag acccgtgagc atctggcgat tttgcagctg
     2881 accggtaacc cgatgctgac agtggcgctg accaaagccg atcgcgtgga cgaagcgcgt
     2941 gttgatgagg ttgaacgcca ggtaaaggag gtgctgcggg aatacggttt tgctgaggca
     3001 aaactgttta tcaccgcagc aaccgaaggt cggggaattg atgccctgcg cgagcatttg
     3061 cttcagttac cagaacgtga acacgccagc caacatagtt tccgcctcgc gatcgaccgc
     3121 gcatttaccg taaaaggtgc cgggctggtc gtcaccggta cggcgttaag cggggaagtg
     3181 aaggtaggcg attcaatctg gctgactggt gtaaataaac cgatgcgcgt gcgtgcgcta
     3241 catgcgcaaa atcagccaac agaaactgcc catgccgggc agcgtatcgc gcttaacatc
     3301 gcgggtgatg cggaaaaaga gcagattaac cgtggcgact ggctgcttgc cgatgtgccg
     3361 ccggagccgt ttacgcgggt gatagtcgag cttcaaaccc atacaccgct gacccagtgg
     3421 cagccactgc atattcacca cgccgccagc cacgttacgg gacgcgtttc gctgctggaa
     3481 gataaccttg ccgagctggt gttcgacacg ccgctgtggc tggcggataa cgatcgcata
     3541 gtgctgcgcg atatctcggc ccgcaacacg ctggcggggg cgcgtgtggt gatgcttaac
     3601 ccgccgcgtc gcggtaagcg taagccggaa tatctgcaat ggctggcgtc tcttgcacgg
     3661 gcgcagagcg atgccgatgc gttatctgtt catctggaac gcggcgcggt taaccttgcg
     3721 gatttcgcct gggcacggca gctcaacggc gaagggatgc gcgaactgct gcaacagcct
     3781 ggctatattc aggctggtta cagcttgttg aatgcgccag ttgccgcccg ctggcagcgg
     3841 aaaattctcg acacattagc gacttatcat gagaaacatc gcgatgaacc tggtcctggg
     3901 cgcgaacgtc tgcgacgtat ggcgttgcca atggaagatg aagcgctggt actgttgctg
     3961 attgaaaaga tgcgtgaaag cggtgacatc ctcagtcatc acggctggct gcatctgccg
     4021 gatcacaaag cgggcttcag cgaagagcag caggccatct ggcaaaaagc agagccactg
     4081 tttggtgacg aaccgtggtg ggtgcgagac ctggcaaaag agacgggaac cgacgagcag
     4141 gcaatgcgtc tgacgctacg tcaggcggcg cagcaaggaa taattaccgc gatcgtcaaa
     4201 gatcgttatt accgtaacga tcggattgtc gagtttgcca atatgatccg cgatctcgat
     4261 caggagtgtg gttcaacctg cgcggcggat ttccgcgatc gcttaggcgt aggccgaaag
     4321 ctggcaattc agattctgga atattttgac cgcattggct ttacgcgtcg tcgtggaaat
     4381 gatcatttat tgcgcgacgc attatt
//
LOCUS       DADXDL010000188         4360 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.188, whole genome shotgun sequence.
ACCESSION   DADXDL010000188 DADXDL010000000
VERSION     DADXDL010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4360
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.188"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            333..923
                     /locus_tag="IRB70_004763"
     CDS             333..923
                     /locus_tag="IRB70_004763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415892.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBC0634566.1"
                     /translation="MSRIFAYCRISTLDQTTENQRREIESAGFKIKPQQIIEEHISGS
                     AATSERPGFNRLLARLKCGDQLIVTKLDRLGCNAMDIRKTVEQLTETGIRVHCLALGG
                     IDLTSPTGKMMMQVISAVAEFERDLLLERTHSGIVRARGAGKRFGRPPVLNEEQKQVV
                     FERIKSGVSISAIAREFKTSRQTILRAKAKLQTPDI"
     gene            complement(1021..1131)
                     /locus_tag="IRB70_004764"
                     /pseudo
     CDS             complement(1021..1131)
                     /locus_tag="IRB70_004764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415891.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            complement(1151..1444)
                     /locus_tag="IRB70_004765"
     CDS             complement(1151..1444)
                     /locus_tag="IRB70_004765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634567.1"
                     /translation="MDITPFLHALCAVAAQVLVGLFTGNWVYGAIAGCTFFIAREHTQ
                     AEYRWIEMFGHGKRMNMPWWGGFDLRAWDVASLMDFAVPVVACLLVWLLVNRV"
     gene            complement(1487..2527)
                     /locus_tag="IRB70_004766"
     CDS             complement(1487..2527)
                     /locus_tag="IRB70_004766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HBC0634568.1"
                     /translation="MANLTVIPDDIKTLKSDVSKLKKDQGSYATKSYVDNKTTWNGYC
                     NVIYDQKTLPTTGTIFSGKIHLSNKTGETENAYGEMYTRKNIDGTKDTMTRIVTHNGT
                     KGIFWDFSDLYGGTLIFPGSDGYLKMGNCLMSYGVRGSNALIKFDCTDTLQIKYANHG
                     STMTINTQGTAHAGVTASLWGNSSRPVVYEVGADGGAYMFYAQKHTDNTYMLSVNGAC
                     HATAFNQHSDRDLKDNIQVIDNATDRIRKMNGYTYTLKENGIPYAGVIAQEALEAIPE
                     VVGSAMKYQDGGSGSKGEEGERYYTVDYSGVTGLLVQVARESDDRITALEEENAELRQ
                     RLSAIEVALASK"
     gene            complement(2538..2816)
                     /locus_tag="IRB70_004767"
     CDS             complement(2538..2816)
                     /locus_tag="IRB70_004767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001546830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634569.1"
                     /translation="MKDFTLKFRDREGYKAFLNEINWEDNEVLQDQLLIDEIGFAFDE
                     VGRNADDEPIYQRRDGYFVNIRILDEKLDASPFTGNVVILDAPLREWA"
     gene            complement(2813..4060)
                     /locus_tag="IRB70_004768"
     CDS             complement(2813..4060)
                     /locus_tag="IRB70_004768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001353818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634570.1"
                     /translation="MIAGFGPGYKKITVRDDVVTIPSDKIVPFSRASSATYINKSGAL
                     TIAEINEPRFEKEGLLIEGQRTNYLKNSNTPELWYYHSLLAKEYGVDNYGFNYATVTV
                     TDSLVGTTSSYQIHSVTGENRFSLSIGETCTFSARFRGVNSRCRVHISLVIGENVKTS
                     VDVCLEPDTGEVKAYGNKALVTFRTEKQGDWCYFETTYTAAENIDEVVCGFFITNPED
                     GGFSSDSSLTMTTPQIEKGPCASSFIISGNTPTTRASDMVIFSTRNNISSVPLSCLVE
                     IHKNWDSTPNQAPRILTTIGVATNDEQLVLAFRTPTSPDVEPLPYVQFGVRSAYLSPS
                     VKAGRKMIAGFVCNSSTEFRCCCNGYLSPVQTSSWKNTGAAHEIRIGGTSAGGERHLF
                     GHVRNLRIWHKELTDAQMGESVE"
BASE COUNT         1194 a         1046 c          846 g         1274 t
ORIGIN      
        1 aaatggtaaa atgtaatata ataaacttac ttttttatca tttttccact ttaacaacat
       61 tttgctccac ttttccacga ccaaacaact tgaaatctgg ttaaaataac acgcaacact
      121 attcttcttc cttgagtccg cccggaactc gaaaaacaaa ccgagttaaa gccttttttc
      181 acaaaatcga ttttgggtct caccaaaatt acggggttgc atacgcattc gtttattttc
      241 gaacgtgtac atacaaatat gcacaaaaat aatcataatt attttctgag atgcattatg
      301 atatgaacac caatttcgta tagagtctca ctatgtctcg aatttttgct tactgtcgga
      361 tatcaacgct ggatcagacc accgaaaatc aacgccggga aatcgaaagt gcaggtttta
      421 aaatcaaacc tcagcaaata atcgaagaac acattagcgg ctcagcagca accagtgagc
      481 gtcctggttt taaccggttg cttgctcgcc tgaaatgtgg tgatcaattg attgtgacaa
      541 aactggatcg ccttggttgt aatgcaatgg atatcaggaa aacagtggaa caactgaccg
      601 aaacaggtat cagagtgcat tgcttagcat tgggtggcat tgacctgacc agtccaacag
      661 gaaaaatgat gatgcaagta atttcagcag tcgctgaatt tgaacgagac cttttacttg
      721 aacgcactca ttccgggata gtaagagccc gcggcgcagg gaaacgtttt ggtcgaccac
      781 ctgtgttaaa tgaagaacag aaacaggtgg tattcgaacg aattaagtca ggtgtaagta
      841 taagtgccat tgcccgggaa ttcaaaacct cgcggcaaac cattttaaga gccaaagcaa
      901 aacttcagac acctgacata taaaaaataa tctcggtgtg agatgcttta cgtcttccaa
      961 gcccccttcc ttgccgtaaa tggaaagata catctaatta tagaatttat atgttttacc
     1021 ctacggcagt gctggccatt caatatcctg tgcagttgac gtatcaacac ggttcagcaa
     1081 tacccgatac tttttccatg cttccagcaa cggggtttct tcctccgttg catatacagc
     1141 tcaccttttt tcacacacga ttaaccaaca gccagaccag cagacacgcc accaccggca
     1201 cagcaaaatc catcaggctt gctacatccc acgcgcgtag atcaaaaccg ccccaccacg
     1261 gcatattcat tcgcttgcca tgcccgaaca tttcaatcca gcgatattct gcctgggtgt
     1321 gttcacgcgc aatgaagaac gtacaaccgg ctatcgcacc gtaaacccag tttccggtaa
     1381 aaaggccaac cagtacctgc gcagccacag cacaaagtgc atgaaggaaa ggtgttatat
     1441 ccattttcat cccacccaat aaaacggggc gctcggcccc ttaatattat ttagacgcaa
     1501 gcgccacctc aattgcagat aatctttgtc ttaattctgc gttttcttct tccagtgctg
     1561 ttattctgtc gtctgactct ctggctacct gaacaagcaa gccagtaaca ccagaataat
     1621 ctactgtgta ataacgttca ccttcttcac ctttcgaccc gcttccacca tcctgatatt
     1681 tcattgcaga gcctacaact tctgggattg cttctagtgc ttcttgcgcg ataacaccag
     1741 cgtaaggtat gccattttct ttaagagtgt atgtatagcc gttcatttta cggatgcggt
     1801 cggttgcatt atcgatcacc tgaatgttgt ctttcagatc ccggtcggaa tgctggttaa
     1861 atgcggtggc atgacatgca ccattaacgc ttaacatata ggtgttatcg gtatgtttct
     1921 gcgcatagaa catatacgcg ccaccatcag caccaacttc atatacaacc ggacggctag
     1981 agttgcccca caagctagca gtaacgccag cgtgagcggt tccttgtgtg tttattgtca
     2041 tggttgaccc atgattagca tatttgattt gtaatgtgtc tgtgcagtca aacttaataa
     2101 gcgcgttact tccccgcaca ccatacgaca tgagacagtt ccccatctta aggtaaccat
     2161 cactgcctgg aaaaattaat gttccaccgt aaagatcgct aaaatcccaa aagatacctt
     2221 ttgttccatt gtgtgtgaca atccttgtca ttgtatcttt tgtaccgtca atattttttc
     2281 tggtgtacat ctcaccataa gcgttttcgg tttctcctgt cttatttgac aagtgaatct
     2341 taccgctaaa tatagttcca gtggtcggca atgtcttttg atcatagatt acattgcaat
     2401 aaccattcca tgttgtttta ttgtctacat atgattttgt tgcgtagctt ccttgatctt
     2461 tttttaattt gctaacgtcg gattttagcg ttttgatgtc atcaggaatt actgttaagt
     2521 tcgccatata ttacccctca agcccattca cgaagaggag catcaagaat cactacattt
     2581 ccggtaaatg gtgatgcgtc cagcttttca tctaagattc taatatttac aaaataaccg
     2641 tcgcgtcgtt gataaattgg ttcgtcgtcg gcatttctgc cgacttcatc gaaagcgaat
     2701 ccaatttcat caatcaggag ttgatcttgc aatacttcat tatcttccca attaatttca
     2761 ttcaagaatg ctttatagcc ttcccgatct cgaaacttca gcgtaaaatc tttcattcta
     2821 ctgactcccc catttgcgca tcagttaatt ctttatgcca tattctcagg ttacgaacgt
     2881 gaccaaacaa gtgacgttct cctccagcag aagttccccc aatacgtatt tcatgtgcag
     2941 ctccggtatt cttccatgac gaagtctgaa caggtgacag gtaaccatta caacagcaac
     3001 gaaattcagt cgagctatta cagacaaaac cagcaatcat tttgcgcccg gccttcacag
     3061 atggactaag atatgcagat ctcactccaa actgaacata aggtaaaggt tctacatccg
     3121 gacttgtagg cgtcctgaaa gccaatacca gttgttcatc attagtcgcc acgccaatag
     3181 tggttaaaat tcgtggggcc tgatttggcg tagagtccca atttttatgt atttcaacaa
     3241 gacagcttaa agggacagaa cttatgttat ttctggttga aaaaataacc atatcactgg
     3301 cgcgcgtggt tggtgtgttt ccggaaataa taaacgatga agcgcatggc cctttttcaa
     3361 tttgcggcgt agtcattgtt aatgacgaat cagaagaaaa accaccatct tcaggattgg
     3421 ttataaaaaa accgcatacc acttcgtcaa tattctctgc ggcggtatat gttgtttcaa
     3481 agtaacacca gtccccctgt ttttccgttc tgaatgtcac cagcgcctta ttaccgtacg
     3541 ccttaacctc acctgtatct ggctccagac atacatcaac ggatgtttta acattttcgc
     3601 caataacaag agatatatgg acgcgacaac gtgaattaac tccacgaaag cgggcagaaa
     3661 aagtgcaggt ttcaccgatg gacagagaaa acctgttctc tccagttaca ctatgaatct
     3721 gataactact ggttgtgcct acaagactgt ctgtcacggt gacggttgca taattaaaac
     3781 cgtaattatc aaccccatac tctttcgcca gtaaactgtg gtagtaccac aattccggtg
     3841 tattagaatt ttttagatag ttagttctct gcccttcaat taacagccct tctttttcaa
     3901 aacgtggctc attaatttct gcaatggtaa gagcgccgga cttattgata taggtcgcgg
     3961 aactcgcgcg ggaaaacggg acaattttgt cggatggtat agtgaccaca tcatcgcgca
     4021 ctgttatttt tttatatccc gggccaaatc ctgcaatcat atccatcgag tcattaaacg
     4081 gtatccacac atcaggcagt ggctgcaaaa cttgtttata cggctcagct gcctggcttg
     4141 cgtactccct ggctgcatct tcacttgctt tagccgctgt ctggcttgca gcggatgctt
     4201 tcgccgagtt agctgccgca gtctcgcttg tctttgcgtt ggtttcactg gtttttgctg
     4261 ctttttgact gttagctgat gcagtggcag aagcagccgc cgcgcttgca gaaccagctg
     4321 caacactctc gctttcggct gctgcatcct ggctgttttt
//
LOCUS       DADXDL010000189         4351 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.189, whole genome shotgun sequence.
ACCESSION   DADXDL010000189 DADXDL010000000
VERSION     DADXDL010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4351)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4351)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4351
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.189"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            23..1387
                     /locus_tag="IRB70_004769"
     CDS             23..1387
                     /locus_tag="IRB70_004769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000701230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634571.1"
                     /translation="MKIPRWVYDRITEITGCVVGDTQWAVTRRQTLRQFLVYIWLEAD
                     DDGWTICTVRDIRSCYASLLSECEINYQGRASISMLVDFLPTLSDIEFRAGKASKDPE
                     KRKASAWLFNPQQPVSDLGKLNLVDLETGESVSFRALLQGNGKAPGHAIDVEKRQTAL
                     KQTEKAFLAKVGRGRMSIQFVKELRSREPDHYYRAGICSLNHLYNGKIEGEYVTYDHH
                     YRLTFGGRYYDQAFQNLPNELKSKFRSGLLNYDIEACNLACLNHLFREYGVDYCVDTS
                     IYAGMMEHTGLSRKQCKQMVHTTTYRIGRVTIGINDGLGAKVYEWCGNSKKKALKILR
                     WWNRYVSPLKSALESLLERVHEVHRENCSSPRNYHRYANEVGLILDLDSEVYQREKTH
                     HQQYARNKALLAFMICGVEQAYIREVVSLNPGRVCMLDHDGVVATGALSLPDWRGFTM
                     KVKD"
     gene            complement(1679..3121)
                     /locus_tag="IRB70_004770"
     CDS             complement(1679..3121)
                     /locus_tag="IRB70_004770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010836078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
                     /protein_id="HBC0634572.1"
                     /translation="MANHIQGQGRHQVTLLPDALDDFVTEDNPVRVVDIFVDGLKLDS
                     LGFRRVDAKRTGRPGYHPATLLKLYIYGYLNRIQSSRRLEKEAHRNVELMWLLERLTP
                     DFKTIADFRKDNGEGIRNACRAFIGLCRQMQMFTDVVVAIDGSKFKAVNSKPNNFTSQ
                     KAKDHIERVEQSITYYLNKLDEADKNTEPDANTKLTATKLAWLKKRLRELQEIQQAVA
                     QQPDKQLSLTDPDSRLMKTNNMNRQVCYNVQTAVDTKNHLIVAHKVTNTTDNGQLGSV
                     ATLAQKAVGRKDITVLADKGYYSRSDIKTVLDSGAVALVPKGDTSGAERKGLYNRSIF
                     RYNREKDVYVCPMGNELQNRFISIEDGLEQHLYFNNIACRDCSQRSRCTTSKRDPRRI
                     RRWVHEAEMEEMHARLESFPQAVVMRKQTVEHPFGTIKMWMGATHFLMRKFKNVSTEI
                     SLHILAYNLKRMISIWGTTGLIFQLQEQYG"
     gene            3089..3205
                     /locus_tag="IRB70_004771"
     CDS             3089..3205
                     /locus_tag="IRB70_004771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007370422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBC0634573.1"
                     /translation="MPALSLNVIGHVGIRSIHSYISNFNEKVSSSHGFIKNG"
     gene            3419..3754
                     /locus_tag="IRB70_004772"
     CDS             3419..3754
                     /locus_tag="IRB70_004772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001059831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634574.1"
                     /translation="MNNIPSMPQLGIYVSKIDPTLRITVTDVDIVDDDDESPDDELFY
                     LVRWIEGEDESDMSAMEFELGPVEWHAFVESEQLVFERDPYMDSAPVNSNLAKIRDLL
                     MKTKQNDRS"
     gene            3956..4339
                     /locus_tag="IRB70_004773"
     CDS             3956..4339
                     /locus_tag="IRB70_004773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013096817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634575.1"
                     /translation="MDTLSIKGILEVFVNNWVPGIFTFFLGICYSNIVEKKKLKQKLK
                     NDILEIFIPVFNAGNEISFEIAENACRKMKGTFQAYKRIYPGIFNKEVESELEDLLKD
                     GFLINGEVNPHYFEPANIENLIKKL"
BASE COUNT         1155 a          899 c         1032 g         1265 t
ORIGIN      
        1 gagtactgaa aaggattatc cagtgaagat cccgagatgg gtttatgatc gtattactga
       61 aataacgggc tgtgtagtag gggatacgca atgggcggtc acccggcgac agacattgcg
      121 ccagttcctg gtctacatat ggctggaggc agacgatgat gggtggacta tatgcactgt
      181 ccgggatatc cgtagttgtt acgccagcct tctaagtgaa tgtgagatca attaccaggg
      241 cagggcctcc atatccatgc tagtcgattt cctgccgaca ctgtcggata ttgaatttcg
      301 tgcagggaaa gcgagtaaag acccggaaaa gcgtaaagcc agtgcatggc tgttcaaccc
      361 gcagcaacca gtgtctgatt tgggtaaatt aaatctggtt gaccttgaaa ccggcgagtc
      421 tgtcagtttt agagctctgc ttcaggggaa cgggaaagct cctgggcatg cgatagatgt
      481 agagaaacgc cagacggccc taaaacaaac ggaaaaggca ttcctggcca aagttgggcg
      541 ggggcgcatg agtatacagt ttgtgaagga attgcgtagc cgtgagccgg atcactatta
      601 ccgcgcaggt atatgcagcc ttaaccatct ctacaatggc aaaattgagg gagaatatgt
      661 tacttacgac catcattatc gtctgacgtt tggagggcgg tattacgatc aagctttcca
      721 gaatctgccc aatgagttga aatctaaatt tcgtagcgga ttactcaact atgatatcga
      781 agcctgtaat ttggcctgtc tgaaccatct gttcagggaa tatggtgttg attactgcgt
      841 agacacttct atctatgcgg ggatgatgga acatacaggg ctgtcccgga agcagtgcaa
      901 acagatggtc cataccacca cctacagaat tggtcgcgtg actattggta ttaatgatgg
      961 ccttggggca aaagtgtatg aatggtgcgg taacagcaaa aaaaaggcgc taaagatttt
     1021 gcgttggtgg aaccgttatg tcagcccttt gaaatccgcg cttgagtcat tgctggaacg
     1081 tgttcatgaa gtacaccgag aaaactgttc atcgccgcgt aactatcaca ggtacgctaa
     1141 tgaagtcgga ttaatactgg atctggatag tgaggtgtat cagcgtgaaa agactcacca
     1201 tcagcaatat gcgcggaata aggcactctt ggcgtttatg atctgtggtg tggagcaggc
     1261 gtatatccgt gaggtagtca gtctgaaccc tggtcgtgtc tgcatgctcg atcacgatgg
     1321 agtagtggca acgggcgctc tttcactgcc ggactggcgg ggtttcacga tgaaggtgaa
     1381 ggactagctt actttcttga atttaactat ctgcgatctc tgataagggc gtattacgtt
     1441 gtggcgtatg cgcattggag cacgatgtgc atatccagca agtgatccac gtccgctttg
     1501 agcgcaggct gtgtgaaaac tcatagcttt gagtagccaa aaaatatttc tcatctgtgt
     1561 tttgagaatg ctgtttaagt tgacgagtta atctgtgatt ttattcgggt gtttcagaga
     1621 tttttattgc gggaaagagc ctaatatttg tttctggagg ataaaacggc cggaaccgtt
     1681 agccgtattg ttcctgaagc tgaaatatca atcctgtagt accccatatc gatatcatcc
     1741 ttttcaggtt ataagccaat atatgtagac ttatttccgt actgacattt ttaaatttcc
     1801 gcatcaggaa gtgcgttgca cccatccaca ttttaattgt cccaaacgga tgttctaccg
     1861 tttgctttcg catgactacc gcctgaggaa atgactcaag cctcgcatgc atttcttcca
     1921 tttcagcttc atgaacccaa cgccgtatac gccttggatc gcgtttcgat gtagtgcacc
     1981 tggagcgctg gctgcaatcg cgacaggcaa tattgttaaa gtataaatgt tgctccagtc
     2041 cgtcctctat tgagataaat cgattctgaa gctcattgcc cattgggcat acataaacat
     2101 ctttttccct gttatatctg aatattgagc gattatagag ccccttacgt tcagcaccag
     2161 aggtatctcc ttttggcact aacgccacgg ctccgctatc cagaactgtt ttaatatcgc
     2221 tgcgactgta ataccctttg tcggcaagta ctgttatgtc cttccggcca acagctttct
     2281 gagccagtgt tgctactgaa ccaagttgcc cattatctgt tgtgttggta actttatgcg
     2341 caacaatcaa gtggttcttc gtatccacag ctgtctgaac gttgtagcaa acttgccgat
     2401 tcatattatt tgttttcatc aaccgggagt cagggtcggt taaagagagt tgtttatctg
     2461 gctgttgtgc gactgcttgt tggatctcct gaagctcacg taaacgcttt tttagccagg
     2521 ccagtttagt ggcagttaac tttgtgtttg catctggctc agtattcttg tcggcttcat
     2581 ccagcttgtt taaataataa gtaatacttt gctcaacgcg ctcaatatgg tctttggctt
     2641 tctgagatgt gaagttgttg ggtttgctgt ttactgcttt aaatttgctg ccgtcgatgg
     2701 caacaacgac atcagtgaac atttgcattt gccggcacag gccaataaag gccctacagg
     2761 cattcctgat accttcaccg ttatcttttc tgaagtctgc aatggtttta aaatcaggcg
     2821 ttaatcgttc aagtaaccac atcagttcaa cgttccgatg ggcctctttt tccagtctgc
     2881 gggaggactg aattcggttg agatatccgt aaatgtacaa cttcagtagg gttgcagggt
     2941 gatatccggg tcgtccggtt cgctttgcat caactcttct gaaaccaaga gaatcgagct
     3001 ttagtccatc aacaaagata tcaacgactc tgacggggtt atcttcagtg acaaaatcat
     3061 ccagtgcatc agggagtaat gtcacctggt gcctgccttg tccttgaatg tgattggcca
     3121 tgtcggtatc cgcagtattc attcgtatat ttctaatttt aatgaaaaag tcagttcgtc
     3181 gcatgggttt atcaagaatg gttgatcata tgaaaccatc gcttagacca agaagtgatc
     3241 aggagttttc acacagcctg agcgaggaac ggaagttcgt tttcaggtaa catactccct
     3301 ctgaaagaga atggggcgtc taagcgggat acttattacg attcttgccg tattcacagt
     3361 aagcacactg tttggcgtat ttttattcga atagcaaaca ctaataaaag gaattctcat
     3421 gaacaacatt ccctctatgc cgcagttagg gatttatgtc tcaaaaatcg atcccaccct
     3481 tcgcatcact gtaaccgacg ttgatattgt tgatgacgat gatgagtctc ctgatgatga
     3541 attgttttat ttagtccgct ggatcgaggg ggaagatgaa agtgatatgt cggcgatgga
     3601 atttgagcta ggcccagtag agtggcatgc ttttgttgag tctgagcaat tagtgtttga
     3661 gcgcgatcca tacatggatt cagcccccgt aaattcaaac cttgcgaaaa tccgggattt
     3721 actcatgaag actaaacaga atgatcgttc gtaagccccc atcaggaaag tggtttagcg
     3781 agtgttatct atttagggca agcggcaaac ggattcgcat gcaattttcc accaaaggtg
     3841 aagcactttc acatgaacgc tgtataataa ataacgtgtt cgaccttcag tttaataccc
     3901 gacttgtacg gggtttgtac tttatgaacc tcaatcttaa ttcaggagta agatagtgga
     3961 cactttgtct attaaaggga ttcttgaagt tttcgttaac aattgggttc ctggtatctt
     4021 caccttcttt ttaggtatct gttactcaaa tatcgttgaa aaaaagaaac ttaagcagaa
     4081 gctaaagaac gatattcttg agatcttcat accggtcttt aatgcaggaa acgagatctc
     4141 attcgaaatc gcggaaaatg cctgcaggaa gatgaaaggt acctttcagg catacaagag
     4201 aatatatcca ggtatcttca acaaagaggt agagagtgaa cttgaagacc tacttaaaga
     4261 tggtttcctc ataaatggtg aagttaatcc gcattacttt gaaccagcca atattgagaa
     4321 tctgattaaa aaattatagt ttcgttcaaa c
//
LOCUS       DADXDL010000190         4347 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.190, whole genome shotgun sequence.
ACCESSION   DADXDL010000190 DADXDL010000000
VERSION     DADXDL010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4347)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4347)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4347
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.190"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..383
                     /locus_tag="IRB70_004774"
     CDS             <1..383
                     /locus_tag="IRB70_004774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634576.1"
                     /translation="DSAGATERKNIDLVETFNYLIGLHVKSIESDIARGYVRIEGTLP
                     TGERTLILWRDCDKIGYEELNKYANRFDLYAKENTFDVIYINGDHNLPTAFTVDEEDG
                     EIVRSLKIRQIEPEFLNLMFAEEV"
     gene            386..3766
                     /locus_tag="IRB70_004775"
     CDS             386..3766
                     /locus_tag="IRB70_004775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001395336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBC0634577.1"
                     /translation="MAKKPTTGKAVKKETNSKLSFHKQLVLNRFMFHFFKDGTLQGLK
                     NRLGEDRFEGIHEDGQSLFFHELSNYLFEVDLIDLDELRRYDLNIVQHWQQITEHRNR
                     KEDTVLNMKYFQYLSLLFTEIYLDWYFNRKQQLLDGLNNELAAYNAENDKTAKDRANQ
                     FKSYVLDDLNKLAYWNATGSGKTLLLHVNILQYLHYFQNGNSHHYPDKIILLTPDERL
                     SKQHLDELENSGFTQYQLFDKSKSAPFKGTIEVIDINKLADEMGDKTVAVEAFEGNNL
                     VLIDEGHKGTGSAAGAWMRRRDKLTRDGFAFEYSATFGQAVAGGNNVEAVETEIQKKK
                     AKLLFETTALGKLSEEQLAQIALTSEEQRDARIQATREVYGKSILFDYSYKFFYEDGY
                     GKESLILNLNPEEDKKDERRYEYFTACLLSFYQQQYLFNKNKEKLNEFNIEKPLWVFV
                     GNTVSGEDSDIHAVLRFLAWFLNHESQAKSWIKDLIENKARILDTKERNIFENRFTAL
                     MNGPEDIYADILSRLFNTTHSGQRLRVLNLIGSKGELALQVGEAEPFGLINIGDAPSL
                     YKMCEEDTTFDYQRDDFAKSLFHTLNDKDSQLHILIGSRKFTEGWSSWRVSTMGLLNM
                     GRGEGSQIIQLFGRGVRLKGRNYSLKRSTPGERPKGLHLEKLETLNVFGVRADYMATF
                     KQYLEDEGITPSDEILELNFETRPNMPATRLKTLKLKDGYKDNQRLGFKRVYFPELYE
                     VPADFQGKIKQPHIKLDLYPKLESIDTSRKGDNTPVNVRNEAKLDYKIISAFDFDRLY
                     LAIQNYKLQRGWSNLRVDKQRLIDFCTGKTKIGNSWYTLLIPASELEIKQYADIAKQE
                     DIMLRLLTDYTDRFYNTLKNAYEGQFYEVTQVKEDDPGMIKMYHFEIEETDDGLAYAS
                     RLEQLQQLVIDGEIGKAKSWSASGMVAITFDKHLYYPLLSIEKNANIPLKMRPAALGA
                     SSEITFVHDLQSFVDSTKGQKIIGDKSLYLLRNADSKNRGLGFATAGNFYPDFLLWLV
                     DDKSGKQWLSLIDPKGIRNLNLDDPKFGLYKEIKNLEHKLSDDNLSLSAFIVSETCYV
                     DLVNVPDSKENLEARNVLFIEDTGSLYLEKLFSKMVSE"
     gene            complement(3813..4115)
                     /locus_tag="IRB70_004776"
     CDS             complement(3813..4115)
                     /locus_tag="IRB70_004776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001507529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634578.1"
                     /translation="MELLNTYDDKETAEIFFERIEGEKRLASERDATETVYNLFGQPT
                     WKNLYLLDMFNLKELQGIIECRKNGQSFDQERHREIIKMLEYAAKSFDLIIPAHWR"
BASE COUNT         1355 a          771 c          917 g         1304 t
ORIGIN      
        1 cggattccgc cggtgccact gagcgtaaaa acatcgattt agttgaaact ttcaattatc
       61 tcattggctt acatgtgaaa tccatcgaat ctgatatcgc acgtggctat gtgcgtattg
      121 aaggaacgct gccaacaggc gagcgtaccc ttattctgtg gcgcgattgc gacaagatcg
      181 gttatgaaga attgaataaa tatgccaacc gatttgattt gtatgcaaaa gaaaacacgt
      241 tcgacgttat ctacatcaat ggcgatcata acttacctac cgcctttacc gttgatgaag
      301 aagacggcga gattgttcgt agcctgaaaa ttcgccagat cgaacctgaa ttcttgaacc
      361 tgatgtttgc ggaggaggtt taagaatggc taaaaaaccg accaccggta aagcagttaa
      421 aaaagagact aacagcaagc tgagctttca taagcagttg gttttaaacc gctttatgtt
      481 ccattttttt aaagatggca cattgcaagg tttgaagaat cggttaggcg aggatcgctt
      541 tgaaggcatc catgaagatg gccaaagctt attcttccat gagctgagta actatttatt
      601 cgaggtcgat cttatcgatc tcgatgaact gcgtcgttac gatctcaata tcgtgcagca
      661 ctggcagcag ataaccgagc accgtaatcg taaagaagac acagtgctga acatgaaata
      721 ttttcagtac ttgtcgcttc tgtttaccga gatctacctg gactggtact tcaaccgtaa
      781 acagcaatta ctcgatgggc taaataacga gctggcagca tacaatgctg aaaatgataa
      841 aacagcaaaa gaccgggcta atcagttcaa atcatacgtt ctggatgatt tgaataaact
      901 ggcatactgg aacgctactg gttctggtaa gacactgcta ttacatgtca atattttgca
      961 atatttacat tatttccaga acggtaatag ccatcattac ccggataaaa tcatcctgct
     1021 tacaccggat gaacgcctat cgaagcaaca tttagatgaa ctggaaaact caggatttac
     1081 ccaataccag ttattcgata agagtaaatc cgcgccattt aaaggcacga ttgaagttat
     1141 tgatatcaat aaacttgccg atgaaatggg tgacaaaact gttgccgttg aggcatttga
     1201 aggcaacaat ctggtcttga ttgatgaagg gcataaaggc acaggaagtg ctgctggtgc
     1261 ctggatgcgc cgtcgtgaca aattaacgcg tgacggattt gcgtttgaat attcagcaac
     1321 ttttggccag gcagtggccg gtggcaataa tgttgaggca gttgaaacag aaattcagaa
     1381 gaaaaaagca aagctgcttt ttgaaacaac tgccttaggt aaactgagcg aagaacagtt
     1441 agcgcaaata gcattaacca gcgaagaaca acgtgatgcg cgtattcagg cgacacgaga
     1501 agtctatggg aaatcgattc tgttcgatta ctcctataaa ttcttctatg aggatggtta
     1561 tggtaaagaa tcactgattc ttaaccttaa tcctgaagag gataaaaaag atgagcgtcg
     1621 gtatgagtat tttaccgcgt gtttgctcag cttttatcag caacaatatt tattcaataa
     1681 gaataaagaa aaattaaatg aatttaatat cgaaaaaccg ctatgggttt ttgtcggtaa
     1741 caccgtaagt ggtgaagatt cagacattca cgcagtactg cgttttttag catggttttt
     1801 aaatcatgaa tcgcaggcaa aatcgtggat taaagatctc attgaaaata aagcgcgaat
     1861 tcttgatacc aaagagcgta acatttttga aaatcgcttt accgcactaa tgaacggccc
     1921 ggaagatatc tacgcagata ttctttctcg tttgtttaac accactcact caggtcagag
     1981 actgcgagtt ctgaatttaa taggcagtaa aggtgaactg gcattacagg ttggtgaggc
     2041 cgaaccgttt ggtcttatca atattggtga tgcaccgtct ctttacaaaa tgtgtgaaga
     2101 ggatacgaca tttgattatc agagagatga ttttgcgaag tcactctttc atacgttaaa
     2161 tgacaaagac tcgcaactac atattttgat cggctcgcga aaatttactg aaggctggag
     2221 cagttggcgc gtctcaacga tgggattgct caatatgggc cgtggagaag gttcacagat
     2281 cattcagtta tttggtcgtg gcgttcgcct taaaggtcgc aattattctt tgaaacgcag
     2341 tacacccggt gagcgtccga aagggttgca tctggaaaaa ttagagacac tgaatgtatt
     2401 cggtgtacgt gccgattaca tggcaacctt taaacaatac ctggaagatg aagggattac
     2461 gccaagtgac gagatccttg agctgaattt tgaaactcgg ccaaatatgc cagcaaccag
     2521 gcttaaaaca cttaagctta aagatggtta taaagataat caaagactcg gctttaaacg
     2581 tgtctatttt cccgaattgt atgaagttcc tgctgatttt caggggaaaa ttaagcagcc
     2641 gcatattaag ctggacctat acccgaaact tgagtcgatt gataccagca gaaaagggga
     2701 caatactccg gttaacgtgc gtaatgaagc gaagttagat tataaaatca ttagtgcgtt
     2761 tgattttgat cggctttatc tcgccattca gaattataaa ctacaacgcg gctggtcaaa
     2821 tttacgtgtg gataaacaac gtttgatcga cttttgtacc ggtaagacaa agatcggaaa
     2881 tagttggtat acccttttga ttccagcttc agagcttgag attaagcaat atgcagatat
     2941 tgctaagcag gaagatatta tgcttcgtct gctgactgat tatactgatc gcttttacaa
     3001 cacattgaaa aatgcttatg aaggtcagtt ttatgaagtc acgcaggtga aagaagatga
     3061 tcctggtatg atcaaaatgt accatttcga gatcgaagaa actgatgatg ggttggcata
     3121 tgccagtcgg ctggaacaat tacaacaatt ggtcatcgac ggcgaaatcg gtaaagcaaa
     3181 atcctggagt gcatccggga tggttgctat tacctttgat aaacatctct attatccact
     3241 tctttcgatt gaaaaaaatg ccaacatacc gctaaaaatg cgaccggcag cactgggtgc
     3301 atcaagtgag attacttttg tccatgatct tcagtctttt gttgattcga caaaagggca
     3361 gaaaattatt ggtgataaaa gtttatatct gctaagaaat gcggattcta aaaatagagg
     3421 cctgggcttt gctactgcgg gtaattttta tccggatttc ttattgtggt tagtcgatga
     3481 taaaagtggt aaacaatggt taagtcttat tgatccaaaa ggcatccgca atcttaatct
     3541 tgatgatcca aagttcggat tatataaaga aatcaagaat cttgaacata aattatcgga
     3601 tgataactta tcattaagtg catttattgt ttctgaaact tgttatgttg acttagtaaa
     3661 cgtacctgat tcaaaagaga atctggaagc cagaaatgtg ctttttattg aggatactgg
     3721 ctcattgtat ctggagaaat tattcagtaa gatggttagc gagtaaataa atatgattct
     3781 gctccatatc tctgtgagat atggagcaga tattatcgcc aatgtgcagg aataattaag
     3841 tcaaacgatt ttgctgcata ttcaagcatt tttattattt cccggtgtcg ttcctggtcg
     3901 aaagactgtc cattttttct acactctata atcccttgta attcttttag gttaaacata
     3961 tcaagaagat ataaattttt ccaggttggt tgcccgaaga ggttatagac tgtttccgta
     4021 gcatctcgtt cacttgctaa tcttttctct ccttctattc tttcaaaaaa tatttcagct
     4081 gtttctttat catcataagt atttaataat tccattatga ttttcctgat taatgaattg
     4141 atatcacgat aattatatca tgaatagatg taaatttact atgtatataa attaatgtac
     4201 agttcaacat gctaattatt ttttaatttg taatgtcgat tggttaataa ttggattctc
     4261 ttataatgaa tatatattta ctctgactag aatatttgta aacgtgtttt atattgagat
     4321 tttaaaattg atttatggct atgtact
//
LOCUS       DADXDL010000191         4298 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.191, whole genome shotgun sequence.
ACCESSION   DADXDL010000191 DADXDL010000000
VERSION     DADXDL010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4298)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4298)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4298
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.191"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            465..617
                     /locus_tag="IRB70_004777"
                     /pseudo
     CDS             465..617
                     /locus_tag="IRB70_004777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000127484.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
     gene            complement(795..953)
                     /locus_tag="IRB70_004778"
     CDS             complement(795..953)
                     /locus_tag="IRB70_004778"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634579.1"
                     /translation="MRAITPLTPARPISDYQTMFSLSQLARELANGTPGQCETLARGA
                     VSARYEMR"
     gene            1207..1722
                     /locus_tag="IRB70_004779"
     CDS             1207..1722
                     /locus_tag="IRB70_004779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001025391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaJ domain-containing protein"
                     /protein_id="HBC0634580.1"
                     /translation="MNIQEALNVFGLSGDLTEKDIKAAYKKAALKYHPDRNPLGAELM
                     KAVNAAFDFLMANIDKINQFQSTDENARYNYGEDLEKVLNTLSGLTGIVYEVIGNWVW
                     ISGETKEHKDILKEMGCKWASKKKQWFYRPEEHKSRWNRKEHSIEEIREMYGTAGKRK
                     ASGWTRVEASA"
     gene            1781..2017
                     /locus_tag="IRB70_004780"
     CDS             1781..2017
                     /locus_tag="IRB70_004780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006122499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634581.1"
                     /translation="MKNKTITEAELINIFESYGAYICPDEIEVTAKECNENGSVLHRG
                     LNAEGWAHLFAKEEAYQQECEAQEAASDDGHFDE"
     gene            2077..2628
                     /locus_tag="IRB70_004781"
     CDS             2077..2628
                     /locus_tag="IRB70_004781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634582.1"
                     /translation="MKEQKNFFERYKPVFEIVCRILGNGWRVNLLDDCQYRIKLTSPD
                     FKNYSIHIRMEKGRLVIIGSVDSRSWRSPYHTCTVSPERNPVEIAADIEKKILSDALD
                     NVDMAREYEQQLQQKREKKLILKGMLSRLVHLESWHGTLTGFKVENGLDGNVSERGDG
                     YEMVIRGLSVDQLIKVAGFIKQL"
     gene            2694..2906
                     /locus_tag="IRB70_004782"
     CDS             2694..2906
                     /locus_tag="IRB70_004782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001446884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634583.1"
                     /translation="MSEDATRLFIELEKLMKVRSKEADKKTTKKIVFQKSFYYEEFSN
                     VKDEIDDPILLKFYTDTIVKVQNHEF"
     gene            2896..3138
                     /locus_tag="IRB70_004783"
     CDS             2896..3138
                     /locus_tag="IRB70_004783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000008707.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634584.1"
                     /translation="MSFKPTPEEVKQARIKAGFTQQEAAERFGFTLSAWQAKETSGKT
                     SRGLAAGTYELLLLLADEHPDYQLVKREKNQDKVTK"
     gene            3232..3570
                     /locus_tag="IRB70_004784"
     CDS             3232..3570
                     /locus_tag="IRB70_004784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634585.1"
                     /translation="MNTYVITFQALNTKKEKITCSAFVHSETLFLAVHSFEDKNRGRG
                     YVITSVSELLSEELTAKNSLKKNINFWFNECGLSKSEVINEVINWKNFAYTLKELEEA
                     KNEAIRELRS"
     gene            3645..3809
                     /locus_tag="IRB70_004785"
     CDS             3645..3809
                     /locus_tag="IRB70_004785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634586.1"
                     /translation="MSERMLSAIQTVEKGGRPVFPLMPFSAFPEYMALLRKALEKKET
                     KALIEKQEVL"
     gene            3806..4063
                     /locus_tag="IRB70_004786"
     CDS             3806..4063
                     /locus_tag="IRB70_004786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001547192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634587.1"
                     /translation="MKKQEFLDFISAEQRRGAVRFSLGFNSKGEIVLHWTNEAGLRVW
                     SILSGNRGKSPSRANRERMSNLRRWLHDARQGMEGDTPEAE"
BASE COUNT         1310 a          886 c         1021 g         1081 t
ORIGIN      
        1 gaaaaatcct ctcaccttta gcaatttttt tccataattt tcaggtaatt gaagcgagct
       61 aagtttttaa gtttttaaga tcaagaagaa aatataaggc ttttaatgca cagcgtctgt
      121 ggataactca gcataaatcc agaggataga tccgtctggc ctccctgagc actgcaccac
      181 caaaaattga gcaaatatta accttagcgc gtaagtgctc tattgaaacc ccgtggaaat
      241 tccgcttcct cgctcactcg cgggcttcgc cctgtcgttc ggctgcggcg agcggtgtaa
      301 tctctctaaa agatccagac gggatccttt tccgatccaa ttcttaaatg ctctcaaaag
      361 ccctcagagg cgttttaacc gctttaaccc ggtcatggtt caacggagcg ggtaaaatgc
      421 gcttagaacg tcatacagct cgtttttaac ctgatcccta atcagggggt ataacagagg
      481 cggccaaaaa atccggcctt gctcgtcaga gtatctaccg cgcattatcc ccgaacggaa
      541 acccgaccat cacaacactt gcacagcttg cagcagtagc cgggttacag ttcactctca
      601 gtaagcccaa ccactaacct ttcagacaag cccctcatac cggggggatt atttcttacg
      661 ccagcaaaat ttcacgaccg gcgaggatgg ccaagtgttt tttgctggca attttcgtgc
      721 agcagctggc gcccggattc attttttgct gtcaggcatc aatcggtttc agcaacccgc
      781 cccgtaattc gctgctaacg catctcataa cgcgcagata cagcgccccg cgccagtgtt
      841 tcacactgac ccggcgtacc gttcgcaagc tcacgcgcta actgcgacag gctaaacatc
      901 gtctgatagt cagaaattgg cctggcaggg gtgagggggg ttatcgctct cattcgggct
      961 tgttggttcg ccagtcctgg cgaacgtctc cggcgcgatg ttacgacagc gcattatgta
     1021 actacagttc gcgcctcttt cggaaatccc ttcatgcgcg gtaaagcaat atacatcttt
     1081 atgtaatctt tacaatgtaa agcattaaaa atgattccat aaccatcatt tgatggtata
     1141 atgaatttgt tggttgggaa tggttccctg ccagattcca gaagcccaca cgggcgggag
     1201 cgaaaaatga atattcagga agcattaaac gtttttggtt tatccggtga tctgactgaa
     1261 aaggacatca aggcggcata caaaaaagcg gctttaaaat atcatccaga ccgcaatcca
     1321 ttgggtgccg agctgatgaa agcagtaaat gctgcgtttg attttctcat ggctaacatt
     1381 gataaaatca atcagtttca aagcactgat gaaaacgcac gttacaacta cggtgaagat
     1441 ctggaaaaag ttctgaatac gctttccggc cttacaggga ttgtctatga agttattggt
     1501 aattgggtct ggattagcgg agaaactaaa gaacacaaag acattttaaa ggaaatgggc
     1561 tgtaagtggg catctaagaa aaaacaatgg ttttaccgtc ctgaagaaca caaaagccgc
     1621 tggaaccgta aagaacacag cattgaagaa attcgtgaaa tgtatggtac agcgggtaaa
     1681 cgtaaggcgt caggctggac acgtgtagaa gcaagcgcat aaccggaatg ggggcgaaag
     1741 ccccctagaa catggcaaag attgattcgg agacacgttg atgaaaaaca agaccataac
     1801 ggaagcggag ctgataaaca tttttgaaag ttacggagcc tacatttgcc cggatgagat
     1861 cgaagttaca gccaaagaat gcaatgaaaa tggttcagtc ttgcaccgtg gcttaaacgc
     1921 agaaggatgg gcgcatcttt ttgcgaagga agaagcatat cagcaggaat gcgaagccca
     1981 ggaagctgca agtgatgatg gacactttga tgaatagtct taaaactgcc gtaattcgat
     2041 ttacggcttt tttattgagt tcaaaaggct gaatcgatga aagaacagaa aaatttcttt
     2101 gaacggtata aaccggtgtt tgaaatcgtt tgtcgaatcc tggggaacgg ctggcgtgta
     2161 aatctgctcg atgattgcca gtacaggatt aagctaacct cacctgattt taaaaattac
     2221 tctatacata ttcgaatgga gaaaggaagg ttagttatca ttggaagcgt agatagtcgc
     2281 agctggagaa gtccttacca tacttgcaca gtatcgccag agcgtaaccc tgtagaaatc
     2341 gccgccgata ttgaaaagaa aatcctgtcg gatgctttag ataatgtaga tatggcgcga
     2401 gagtatgaac aacagttaca gcaaaaacgc gagaaaaaac tgatcctgaa aggaatgcta
     2461 tctcgtttag tgcatcttga aagctggcat gggacattga ccgggtttaa agttgagaat
     2521 gggttagatg gtaacgtatc agaacggggc gacggatatg aaatggtaat tcgtggcctg
     2581 agtgtagatc agctcataaa ggtagcgggg tttattaaac agctatgagg caaaaaatga
     2641 atgaagtcct gagcgacagg aaaaacaaag gtaatgtaac atacaggatt gttgtgtctg
     2701 aagatgcaac acgtttgttt attgaacttg aaaaactgat gaaggtacgc tctaaagaag
     2761 cggataaaaa aacaactaaa aagattgttt tccaaaaatc attttattac gaagaattct
     2821 cgaacgttaa agatgaaatt gatgatccaa ttttattgaa attctataca gatactattg
     2881 tgaaggtaca aaatcatgag ttttaagcca acacctgaag aggtgaaaca agcacgtatt
     2941 aaagctggct ttacgcagca ggaagccgct gaacggtttg gttttacgtt atcagcctgg
     3001 caagccaaag aaacatccgg taaaacgtct cgtggtttag ccgctggtac gtatgaatta
     3061 cttttgctcc tggctgatga acatccagat taccagctcg ttaagagaga aaaaaatcag
     3121 gataaagtga ctaaataaat tgcattacca tcatatgatg gtataattta tttgtaggtc
     3181 gggaatagtt ccttaccatg atccagtagc ccaaacgggc gggagactaa aatgaacacg
     3241 tatgttatca ctttccaggc tttaaacact aagaaagaaa aaatcacctg ctctgctttt
     3301 gtccattcag aaactctctt ccttgccgtt cattctttcg aagataaaaa tcgcggtcgt
     3361 ggttatgtta tcacgtctgt tagtgaattg ttgtccgagg aactgacggc gaaaaattcc
     3421 ctcaagaaaa atattaactt ttggtttaat gagtgtggtt taagtaaatc tgaggttata
     3481 aacgaagtaa ttaactggaa gaatttcgca tataccctta aagaactgga ggaagccaaa
     3541 aatgaagcga taagagaact gcggagttaa tcaattaggg gtggtatcag gttgtggagg
     3601 caacctgata ccgtgacact caattccctc gcgaggaata taaaatgtcg gaacgcatgt
     3661 tatcagcaat acagactgtt gaaaagggtg ggcgtccggt ttttcccttg atgccattct
     3721 ctgcttttcc tgagtacatg gcattactca gaaaagccct ggaaaagaaa gaaacaaaag
     3781 cactgataga aaaacaggag gtgctatgaa aaaacaggag tttttagatt ttatcagtgc
     3841 agaacagagg cggggagctg tccggttttc gctgggattt aacagcaaag gggaaattgt
     3901 attgcactgg actaacgagg ccgggttaag agtctggagt atactaagcg gtaacagggg
     3961 aaaaagtccc agccgggcaa accgggaaag aatgagtaac ctccgccgct ggctccatga
     4021 tgcccggcag ggcatggaag gcgacacacc agaggcagaa taaaattccc gttcctgaat
     4081 cgccgaagcc ctcccgttta cgggaggtgc tttttttgta tattccgtaa aacagcgctc
     4141 gcgccccctg ccaggccatt cgcgtagcga atttatttcc gcccaagtta gccgcgaatc
     4201 cgttgtctcc ggtcgcagac gcaccagatc acagccacga tagcctttca ttttttgcat
     4261 ttcgatggac gctgaagcac aatttatgtg tggaggta
//
LOCUS       DADXDL010000192         4216 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.192, whole genome shotgun sequence.
ACCESSION   DADXDL010000192 DADXDL010000000
VERSION     DADXDL010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4216)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4216)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4216
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.192"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            437..2218
                     /locus_tag="IRB70_004787"
     CDS             437..2218
                     /locus_tag="IRB70_004787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001600713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YopB/SseC family type III secretion system
                     translocon subunit"
                     /protein_id="HBC0634588.1"
                     /translation="MSAPITGQTITFEQISETLRTQYSDAEKRLQDSSKTQVDPMRLN
                     KNPKSLDNDIRARLENKPMLAPPEIQVSDSDNATTAKTNDARLTMILGNLTGIADQDI
                     TKRLHNNLDSTLLRHEMAHNKFRELSDAYSSSLDDAQKADDIMHQANNNYNAVDKKVQ
                     SLEKKVNTLNQELSQLQPGDPQYNKVLTQKNAAEKTLTLSLQKKSLAEKSLNTAIMDA
                     DAAIGQSMEIFDEIQQQEQINNFTTNICLTQENQKNRNATATFILLITSVMEVIGDTN
                     CDSIKNQSEVMKEINHVRENKLNETARKYTTTTKVLKIVNECVTVVTFAVSAVLIVVG
                     LLAAVPSGGSSIAGALALIGGIAGAVVLGVDITCQIALGTTATGWILGKVVEGLSAAI
                     KTVDPTLLAITALLDVIGVDQDTIELVKSIYASAAASIVMATVMIGAAVICSVAIGAV
                     VSALSKTAAEEVTKEITSTIKSTIESIINSVSKNIIKVLDSVCSVLQTSAVVLKLIAK
                     ISNGLEKIGLLICAIATSTMNCFVAGNSADMAILQQDMSNLSKTREQMLSVLQRVDKT
                     VEQEVSQMVRVLQHRTEALKFASHSIV"
     gene            2231..3382
                     /locus_tag="IRB70_004788"
     CDS             2231..3382
                     /locus_tag="IRB70_004788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000257045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634589.1"
                     /translation="MATYEIKNATSIHNINNLDKTIFDRDYGKENNIPNDNKIVQYYN
                     LKDIKHDISSQFIILKNTDREVCPELRVKLLDNLNYSRNTLDNLRGDLDQATISFSQS
                     SSSAEQSSIKISKYNILDMLDNLTMRQQAVMEEFLRVFTSMYKASAMSEAIMSNVFEQ
                     LVQYQKTETVHATMASSAGVLAGSTVGAAGAAASVVANFRSHPEKMQTLTPDQKHTIS
                     GTDDKTQRGLKREVQDQQAYLKQIDEEIKTTTKDTTLDEEQKEETLKYYDKEKETTEE
                     KIRDKNERISIKHNRKYNKYFTIGKADVLSQLVNQSTQASLRILESTTHAEKDIVEQA
                     KNVMHSVMSSYLDQINRDVQGRDQALNLLQQIIQTIIDTDSAIVQGIRS"
     gene            3426..>4216
                     /locus_tag="IRB70_004789"
     CDS             3426..>4216
                     /locus_tag="IRB70_004789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IpaD/SipD/SspD family type III secretion system
                     needle tip protein"
                     /protein_id="HBC0634590.1"
                     /translation="MINKDNNLNIDILRQQNANIPLQEASSQSEEPHQLENSKSEGNL
                     HNSASKDNNIGAMLKKDVEKLSTLVSERSPRNEDWKCQHDIQLNFVKNMLRNFPTENL
                     SEKGSALLHESYSLIKNVLQLTENVNTIDGKLKDPAKILTLHNSVRKTLANVAHNTTG
                     SSAMASTKGTLNHAIASLESSAPEMRSSATSSTLTASSSNEFKSDKYICSDIADLMSV
                     LGSDYLEIYANSVEIMSAYWQDFSEHIQSNMGKWTHSNKKGDAIV"
BASE COUNT         1536 a          773 c          833 g         1074 t
ORIGIN      
        1 ccgataacga tttctctttg gtttattata tgggtcaatg ccagatgggc ttaaaaaaca
       61 ttaaaatggc cactgagtta tttaatactg tcgtaaccta tagtcaaaat gaaaaaatta
      121 aagagatggc tactgcttat cttgaacttt tgacagccaa taccgaagag gaagttcgaa
      181 cagagtgagt cggcaaaatg aacataaacg gaaaaaacgc ttcttttacg tctgaagagt
      241 tagccaggaa atatcatgag gaaggcacag ttgatttaaa aaaataacca tggcgataaa
      301 ataaatgaga agaataacaa taaacacatt acttactttc ccgttgatgc cattttagat
      361 gggaataaac atctgccatg agttaaataa aaaagaatta attacacccg atgatagctt
      421 aaaaaggagg tgaattatgt cggcaccgat tacgggacaa acgatcacgt ttgaacaaat
      481 cagtgaaaca ttgcgtacac agtatagcga tgcggaaaaa agactgcagg acagcagcaa
      541 aacgcaagtt gatcccatgc ggcttaataa aaacccgaaa tcccttgata acgatattcg
      601 cgctcgtctt gaaaacaaac cgatgcttgc tccgcctgaa atacaggttt cagattcaga
      661 caacgccact acagcaaaga cgaatgatgc ccgcctgaca atgattttgg gtaatttaac
      721 aggcattgcc gatcaggata ttacaaaacg attgcataat aaccttgaca gcaccctgct
      781 tcgacacgaa atggcacata ataagtttcg tgaattaagt gacgcttatt cctcgtcatt
      841 agatgatgcg caaaaagccg acgatatcat gcatcaggcc aataataatt acaatgcggt
      901 cgataaaaag gtgcaatcgc tggagaaaaa agtcaacaca ttgaatcaag agctgtcgca
      961 actgcaacct ggcgatccgc aatataataa agtactgacg caaaaaaatg cggctgaaaa
     1021 aacactcacg ctgtcattac aaaaaaaatc gttagctgag aaatcgttaa atacagccat
     1081 tatggatgct gatgctgcga tcggccaaag tatggaaatt tttgacgaaa ttcaacagca
     1141 agaacagatt aataacttca ccaccaatat ttgcctgaca caggaaaacc agaaaaatag
     1201 aaacgcgaca gccacattta tccttttgat tacttcagta atggaagtta ttggtgatac
     1261 caattgcgac tctattaaaa atcaatctga ggtaatgaaa gagattaacc atgtcaggga
     1321 aaataaactc aatgaaacag cacgtaaata tactaccacg actaaagttt taaaaatcgt
     1381 taatgagtgt gtaactgtag ttacctttgc cgtaagcgca gtcttaattg ttgttggtct
     1441 tcttgctgca gttccaagtg gtggttcaag tattgcgggt gcattggcac ttattggagg
     1501 aatagcgggc gcagtagtat taggtgtaga tatcacttgt caaatcgctc tgggcaccac
     1561 ggctaccggc tggattttag ggaaagttgt tgaaggtctt tcggctgcga ttaaaacagt
     1621 tgatcccact ctgctcgcaa tcaccgcgct tctggacgtt attggtgtcg atcaagatac
     1681 gattgaactg gttaaaagta tttacgcaag tgcagccgct tctattgtca tggcgacagt
     1741 aatgattggt gcagctgtaa tatgttctgt agcaataggg gccgttgttt ctgcattatc
     1801 aaaaacagcc gccgaagaag tcaccaaaga aataacaagc actataaaat caaccattga
     1861 atccattatt aattcagttt caaaaaatat tataaaggta ttagacagcg tatgcagcgt
     1921 gctacaaaca tcagccgtag tgttgaagtt gattgccaaa ataagtaatg gcctggagaa
     1981 aataggctta ctcatctgtg caatagcaac atcgacgatg aattgttttg ttgctggaaa
     2041 ctctgccgac atggcaattt tacaacagga catgagtaat ctatcaaaaa cgcgtgaaca
     2101 aatgctttca gtattgcaaa gggtggataa aaccgtcgaa caagaggtaa gccagatggt
     2161 aagagtatta caacaccgaa ctgaagcctt aaaatttgct tcccattcta tcgtataaga
     2221 gggttttaac atggccacct atgaaattaa aaatgcgacc agcatacata atattaacaa
     2281 tctcgataaa acaatctttg atagagatta tggtaaagaa aacaacatac caaatgataa
     2341 taaaattgtg caatactata accttaaaga tattaagcat gacataagct ctcagtttat
     2401 aatattaaaa aatacagaca gagaagtctg tccggaacta agagtaaaac ttttggataa
     2461 tcttaattac tcaaggaata cgctagataa tttgaggggt gaccttgacc aagctacaat
     2521 ttcattcagt caatcaagca gttctgcaga acagagttct attaaaatat ctaaatataa
     2581 tatccttgat atgctagata atttgaccat gcgacaacag gctgttatgg aggaattttt
     2641 aagggtattc acatcaatgt ataaagcctc tgctatgtct gaggctatta tgagcaacgt
     2701 ttttgaacaa cttgtccagt atcagaaaac agaaaccgta cacgccacaa tggcaagttc
     2761 ggcaggtgtt cttgccgggt caacagttgg cgcagctgga gctgcagcat ctgttgtagc
     2821 aaatttcaga agccatcccg aaaagatgca aacccttaca cctgatcaga agcacactat
     2881 cagtggaact gatgataaaa cacagcgagg attaaaaagg gaagttcaag atcaacaagc
     2941 ttatctcaag caaatagatg aagaaataaa aacaacaacg aaagatacaa cacttgatga
     3001 agaacaaaaa gaagagaccc tgaaatatta cgataaagaa aaagaaacta cggaagaaaa
     3061 aattagagat aaaaacgagc gtattagtat aaaacataac aggaaatata ataaatattt
     3121 tactataggt aaagcagatg tactttcaca gcttgttaat caatcaactc aagcatcact
     3181 tagaattcta gaaagtacta ctcatgcaga aaaagacatt gttgaacagg ctaaaaatgt
     3241 catgcattca gttatgagta gctatctgga tcaaattaat cgtgatgttc aaggaagaga
     3301 tcaggcactc aatttattac agcaaataat acaaaccatt attgatactg atagtgctat
     3361 tgttcaagga attcgctcat aaattattgc aataatagtt tcttatattt aaggaggaat
     3421 gacacatgat taataaagat aataatttaa atatagatat tctacgtcag cagaatgcaa
     3481 acattcctct tcaagaggca tcctcgcaaa gtgaggagcc tcatcaactg gaaaacagca
     3541 aaagcgaggg taatttgcat aacagcgcca gtaaggataa taatattggc gctatgctca
     3601 agaaagatgt tgaaaaacta tcaactttag tcagtgaacg tagcccgcga aatgaagact
     3661 ggaaatgcca gcatgacata cagcttaact tcgttaaaaa catgctcaga aatttcccaa
     3721 ctgagaacct gtcagagaaa ggatctgcgc tcttacacga aagttattcg ctgataaaaa
     3781 acgttctgca gcttacagaa aatgttaata ctattgacgg aaaattaaag gatcccgcta
     3841 aaatattgac cttgcataac tctgtgagaa aaaccctggc taacgttgct cacaacacaa
     3901 ccgggtcaag tgcaatggca tcgaccaaag gtaccttaaa tcacgctatc gcttctttag
     3961 agagttctgc gcctgaaatg agaagttcag caaccagcag tactttaacg gccagtagtt
     4021 caaacgaatt taaaagtgat aaatatatat gcagtgatat tgctgatttg atgagtgtgc
     4081 tcggtagcga ctacctcgaa atctatgcaa atagcgttga gataatgagc gcatactggc
     4141 aggacttcag tgaacatatc caaagcaata tgggaaaatg gactcactct aataaaaaag
     4201 gcgatgcgat agtttt
//
LOCUS       DADXDL010000193         4160 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.193, whole genome shotgun sequence.
ACCESSION   DADXDL010000193 DADXDL010000000
VERSION     DADXDL010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4160)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4160)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4160
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.193"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..3168
                     /gene="air"
                     /locus_tag="IRB70_004790"
     CDS             <1..3168
                     /gene="air"
                     /locus_tag="IRB70_004790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inverse autotransporter adhesin EaeX/Air"
                     /protein_id="HBC0634591.1"
                     /translation="GNGATVAPTVITGQDGTVEISVTSQTAGVSAVTATINNSSQSRN
                     VMFIADVRTAQIADLVVIKDDSVADGSTANTLRARVTDAFGNMLAGQTVSVLADNGAT
                     TAPTVITEPDGTVELSVTSQTAGTSAVTASINNSSQSRNVTFIADVRTAQIASLVVIK
                     DGSEADGATANTLRARVTDAFGNALAGQTVSVSAGNSATVAPAVITEPDGTVEISVTS
                     QTAGVSAVTATINNSSQSRNVTFIADVRTAQIADLVVTRDNSVADGSTANTLQVKVTD
                     ANGNTLAGQTVSVLAGNSATVASTVTTKPDGTVEISVTSQTAGTSTVTASINNSSQSQ
                     NVTFVPGDASQLTSTVETNKSNYTVGETITITVTLRDAFDNLVTGAASQLAANGVLAV
                     DGTDPSETGSWVESGGVYTTTRMATIASTNQHANLQLQTWSDGVTSDRYDIQSGSPAQ
                     ATSTIATDKNAYTAGDTITVAVTLKDAHGNQVEGGESLLSGDNVTVEGAVRSGGWSET
                     AGVYTATWSAQMAGDSHHATLKLSEWGSSKQSESYSIHSGAPVQANSAIRTDKSAYIA
                     GEPLTVTITLRDEFGNPALGLTSEVIESYIDNFAVGGATPDSMRWVEQNNGEYTIVWT
                     AWVAEENLVASLKLKTWAEEIKSSLYGIQPGAAAKNQSTIVTDKTIYIAGDSITVTVV
                     LKDAQGNFITDGVVQLNEENVQVRNADPIQGNNWVYNGNGQYQRQYMAHFAEANLNAQ
                     LKMAGWSDANYSNNYTIKPGEVSPLGSQLRIREVLVVEGADLPVSVLLVDDFGNPVDN
                     GLDLLDDTVYLQNVEKKEGEKWRYVGDGIYERTYMAYQEGENLTSFMEIKGWRIYGQP
                     SYTILPFVEVELLSVNGVKFRATDGFPETGFDGAKFTLLLTHNMKNTDYNWTAGIYGI
                     NVDSNGEVTLSVLIRSEVTITGKPKNGKGNDVVFKFKIKKWFTSLGATSSNTWDIINT
                     SCSYGQMPSSLELAQRPSGGVVPRKVGTLWGEYGNLKIYGNAFSGTDYWTSTQLMGVH
                     EKFNPETGISELGTGKSSGLCVEYY"
     gene            complement(3220..>4160)
                     /gene="eilA"
                     /locus_tag="IRB70_004791"
     CDS             complement(3220..>4160)
                     /gene="eilA"
                     /locus_tag="IRB70_004791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="HilA family transcriptional regulator EilA"
                     /protein_id="HBC0634592.1"
                     /translation="SLDSAVMYMNGRMEMYRYTPESLKRALVIFRDCVSTQPQNTLPY
                     CCLAECHISLALLGISEQKQAITTAVTSIEKALEINPSNSQALGLLGLISGLKDEHSV
                     SNVLFKQAHLLKPNSPDVYYYQSLLCFLNGDLARAFNLIEKSIALEPNKMGISILKLI
                     ILYYTSPLDNAISFALNLNSQNTCNNPIITSILAMFMALKGHNDKAKSLLLKLEPEHG
                     LDYTCVNSLYTKFLIYGASIKNDIMKLLANINTNKINGVILPLIYTVYGKKEYEKRWQ
                     QLIKENDLWSNVLLHDPRLLSVKNEFNTIGVMRTSA"
BASE COUNT         1186 a          873 c         1092 g         1009 t
ORIGIN      
        1 ggcaacggcg caacggttgc cccgactgtc atcacagggc aggacggtac ggtggagatc
       61 tcagtcacca gccagacggc gggagtcagt gcagtcactg cgaccatcaa caacagcagc
      121 cagagccgga acgtgatgtt tatcgccgat gtcaggacgg cgcagatcgc ggacctggtg
      181 gtcattaagg acgactcagt ggcagacggt tcgacggcaa acacgctgcg ggcgagggtg
      241 accgatgcgt tcgggaacat gctagccggg cagacggtca gcgtgttggc ggacaacggc
      301 gcaacgactg ccccgacggt catcacagag ccggacggta cggtggagct ctctgtcacc
      361 agccagaccg ccggaaccag tgcggtcacc gccagcatta acaacagcag ccagagccgg
      421 aacgtcacgt ttatcgccga tgtcagaacg gcgcagatcg cgagtctggt ggtcattaag
      481 gacggttcag aggcggacgg tgcgacggcg aacacgctgc gggcgagggt gaccgatgcg
      541 ttcggcaatg cacttgccgg gcagacggtc agcgtgtcgg caggcaacag cgcaacggtt
      601 gctccggcgg tcatcacaga gccggacggc acggtggaga tatctgtaac cagccagacg
      661 gcgggagtca gtgcagtcac tgcgaccatc aacaacagca gccagagccg aaacgtgacg
      721 tttatcgccg atgtcaggac ggcgcagatc gctgatctgg tggtcacccg ggataactca
      781 gtggcagacg gttcgacggc gaatacgctg caggtgaagg tcaccgatgc taacggtaat
      841 acgcttgccg gacagacggt cagcgtgttg gcgggcaaca gcgcaacggt tgcttcgacg
      901 gtgaccacaa agccggacgg cacggtggag atcagtgtca ccagccagac ggcgggcacc
      961 agtacagtca ccgccagcat caacaacagc agccagagcc agaacgtcac ctttgtacct
     1021 ggtgatgcat cgcagctcac ttcaaccgtt gaaacaaata agtcgaacta tacggttgga
     1081 gagacaatca ccatcacggt aacgctccgg gatgcgttcg ataatctggt aaccggtgca
     1141 gcttcacagt tagccgctaa tggtgtgctg gcggtggatg gcaccgaccc gtcagaaacg
     1201 ggaagctggg ttgaatcagg tggcgtgtat accacaacac gaatggcgac gattgccagt
     1261 accaatcagc acgccaacct gcaattgcag acgtggagtg atggcgtaac gtcagatcgc
     1321 tatgacatac agtccggttc tccggcgcaa gccacatcaa ctatcgctac ggataaaaac
     1381 gcctacaccg ctggcgacac tataaccgtc gccgtgacgc tgaaagacgc gcacggtaac
     1441 caggttgaag ggggcgagtc cttattgtct ggtgataacg taacagtaga aggagccgta
     1501 cgttcaggag gatggtctga aaccgccggt gtttatactg ctacatggtc ggcgcaaatg
     1561 gcgggagact ctcaccacgc gacgctgaag ttgtctgaat ggggcagcag taaacaatca
     1621 gagagttatt ccatccacag cggtgctccg gtgcaggcaa attctgctat caggacagat
     1681 aaatcggcat atatcgccgg ggagccatta accgtcacaa taacgttgcg ggatgagttt
     1741 ggtaaccctg ctttagggct gacatcagaa gtcatcgagt cttatatcga taatttcgcg
     1801 gtaggcggcg caactcccga ttctatgcgg tgggtcgagc agaataatgg tgaatatact
     1861 attgtctgga cagcatgggt tgccgaggaa aatctggttg ccagtctgaa attaaaaaca
     1921 tgggcagagg agattaagtc ctcgttatac ggaatacaac caggtgcagc ggcaaaaaat
     1981 caatccacga ttgtcacgga caaaacgata tatatcgctg gggatagcat aacggtaacc
     2041 gttgttctta aagacgccca gggtaacttt attactgatg gtgtcgttca gcttaatgag
     2101 gaaaacgtac aagtcaggaa tgcggatcct atccagggca ataattgggt ttacaacggc
     2161 aatgggcaat atcaaagaca gtatatggcg cattttgcgg aagcgaattt gaatgcgcaa
     2221 ctgaagatgg ctggttggag cgatgccaat tattcaaaca attacactat caaaccaggt
     2281 gaagtgagtc cgcttggttc acagcttcgt atacgagaag ttttagtagt ggaaggggcg
     2341 gatttacctg tcagtgtttt attagttgat gattttggaa atccggtgga taacggtctg
     2401 gatttgctgg atgatacagt gtacttacaa aatgtagaaa aaaaagaagg ggaaaaatgg
     2461 agatatgtgg gtgatggcat atatgaacgt acatatatgg cctaccaaga aggagaaaat
     2521 ttaacttcat ttatggagat taaaggttgg cgtatatacg gacaaccatc ctataccatc
     2581 cttccttttg tggaagtcga gttgctgagt gttaatggtg taaaattcag ggcgacagat
     2641 ggttttccag aaacagggtt tgatggtgca aaattcacgc tgttactaac ccataatatg
     2701 aaaaatacgg attataattg gacggctggg atttatggaa ttaatgttga cagtaatgga
     2761 gaagtaacat tatctgtgct gataagaagt gaagttacta ttaccgggaa acccaagaat
     2821 ggtaaaggga atgatgttgt atttaaattc aagattaaaa aatggtttac tagtttaggt
     2881 gctaccagta gtaatacctg ggatatcata aacacttcat gtagctatgg tcaaatgccg
     2941 tcatctttag aattagcgca gcggccaagc ggtggggtag taccgcgaaa agtaggtacg
     3001 ttgtggggcg aatatggtaa tttaaaaatt tatgggaacg cttttagcgg tacggattat
     3061 tggacaagca ctcagctcat gggagtacac gagaaattta atcctgaaac tggtatatca
     3121 gagcttggaa caggaaagtc ctctggcttg tgcgtagagt attattaacg aagtaatcac
     3181 taaattgccc tgcatcagca gggcaattta tattcgttat tacgcagaag tacgcatcac
     3241 accaatagta ttaaattcat tttttacact gagcaaacgg gggtcatgaa gcaaaacatt
     3301 tgaccataaa tcattctctt taattaattg ttgccagcgc ttttcatatt ctttcttacc
     3361 ataaacagtg taaattaacg gcaaaatcac accattgatt ttgttagtgt taatatttgc
     3421 cagtaacttc ataatgtcat tttttataga tgcgccatag atcagaaact tcgtataaag
     3481 cgagttaacg caggtgtaat caagaccatg ttcaggctca agtttaagca ataaactttt
     3541 ggctttgtca ttatgtcctt tcagtgccat gaacatagcc agaatagagg taataattgg
     3601 attattacag gtgttttgac tgttaagatt taatgcaaaa gatatcgcgt tatcgagggg
     3661 ggatgtgtaa taaagtataa ttaatttaag aatgcttatg cccattttat tgggttcaag
     3721 agcaatgctt ttttctatta aattaaatgc tcttgctagg tcaccgttca aaaaacatag
     3781 cagagactga taataataaa cgtctggcga attaggtttg agtaaatgtg cttgcttaaa
     3841 tagcacatta gacactgaat gttcatcttt tagcccactg attaaaccca gtaaacccaa
     3901 tgcctgagaa tttgaagggt taatttccag agccttttca atggaggtta ctgccgtagt
     3961 tattgcttgt ttttgttcac tgattccaag gagtgctaat gatatatggc attccgccag
     4021 gcaacagtag ggcaaggtat tttgcggttg cgtactcaca caatctctaa atattactaa
     4081 tgctcgtttc aaactttctg gtgtataacg gtacatttcc atcctgccat tcatatacat
     4141 aacagcagaa tccagagatg
//
LOCUS       DADXDL010000194         4126 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.194, whole genome shotgun sequence.
ACCESSION   DADXDL010000194 DADXDL010000000
VERSION     DADXDL010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4126)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4126)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4126
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.194"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            643..1620
                     /locus_tag="IRB70_004792"
     CDS             643..1620
                     /locus_tag="IRB70_004792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052630.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBC0634593.1"
                     /translation="MDKSSGELVTLTPNNNNTVQPVALMRLGVFVPTLKSLKNSKKNT
                     LSRTDATEELTRLSLARAEGFDKVEITGPRLDMDNDFKTWVGIIHSFARHNVIGDKVE
                     LPFVEFAKLCGIPSSQSSRRLRERISPSLKRIAGTVISFSRTDEKHTREYITHLVQSA
                     YYDTERDIVQLQADPRLFELYQFDRKVLLQLKAINALKRRESAQALYTFIESLPRDPA
                     PISLARLRARLNLKSPVFSQNQTVRRAMEQLREIGYLDYTEIQRGRTKFFCIHYRRPR
                     LKAPNDESKENPLQPSPAEKVSPEMAEKLALLEKLGITLDDLEKLFKSR"
     gene            complement(1905..2645)
                     /locus_tag="IRB70_004793"
     CDS             complement(1905..2645)
                     /locus_tag="IRB70_004793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBC0634594.1"
                     /translation="MNNVIPLQNSPERVSLLPIAPGVDFATALSLRRMATSTGATPAY
                     LLAPEVSALLFYMPDQRHHMLFATLWNTGMRIGEARMLTPESFDLNGVRPFVRILSEK
                     VRARRGRPPKDEVRLVPLTDISYVRQMESWMITTRPRRREPLWAVTDETMRNWLKQAV
                     RRAEADGVHFSIPVTPHTFRHSYIMHMLYHRQPRKVIQALAGHRDPRSMEVYTRVFAL
                     DMAATLAVPFTGDGRDAAEILRTLPPLR"
     gene            complement(2766..2948)
                     /locus_tag="IRB70_004794"
     CDS             complement(2766..2948)
                     /locus_tag="IRB70_004794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001312821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein kinase"
                     /protein_id="HBC0634595.1"
                     /translation="MHVAQLPSLCIFLLSLRSSLPWHYPISPKNGKPALSPRHDWLNT
                     GSLLQNIPLRIWFYPQ"
     gene            complement(3291..3598)
                     /locus_tag="IRB70_004795"
                     /pseudo
     CDS             complement(3291..3598)
                     /locus_tag="IRB70_004795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_461876.3"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system ParD family
                     antitoxin"
BASE COUNT         1078 a          986 c          990 g         1072 t
ORIGIN      
        1 tgtagtttgt atacacaatc cctggcattg aaacacacat atgaagtgta cttcggatat
       61 gaccgtacgc tcaggaagta cggcagattc cgtcaaaaat tacctgtaaa gacagacatc
      121 agaaaaaaca gtgctcgccg cagaccggtg accgggcgaa gcccgcgaac cggcgaggaa
      181 gcgcaatgta tctgtagtta cagggagcag gtacgccctg aagccctttc ataaaacggt
      241 tgtgtgcgct gtccttctgg aatgatttat ccacatatcc ggaggcccga tccagtaaac
      301 agatccatga atgatcaaca aaggatccat taaagatccc catatcgctg caaaccttgt
      361 cactcatggg ccgggaccac gatcacataa gctgtggcat gttactgata aactgtaaca
      421 tgctaatgat aagctgtatt cagtaatcca tatactgaag taagttaatg acataaacta
      481 tggtcagtat gccagactca gttgttaaat acaggctgca ggtttttctt cagtcagtta
      541 gcggagttct gacacacgat tttctgttta ttcttttact gtccacaggc tggaggcttt
      601 ctggaaaacg aaaattcaga catcaaaaaa ctgttcggcg aggtggataa gtcctccggt
      661 gagctggtga cactgacacc aaacaataac aacaccgtac aacctgtggc gctgatgcgt
      721 ctgggcgttt ttgtaccgac ccttaaatca ctgaagaaca gtaaaaaaaa tacactgtca
      781 cgtactgatg ccacggaaga gctgacacgt ctttccctgg cccgtgctga gggattcgat
      841 aaggttgaga tcaccggccc ccgcctggat atggataatg atttcaagac ctgggtgggg
      901 atcattcatt cctttgcccg ccataacgtg attggtgaca aagttgaact gccttttgtt
      961 gagtttgcaa aactgtgtgg tataccttca agccagtcat cccgcaggct gcgtgagcgc
     1021 atcagccctt ccctgaagcg cattgccggt accgtgattt cgttttcccg taccgatgag
     1081 aagcacaccc gggaatatat cacccatctg gtacagtcag cttactacga tactgagcgg
     1141 gatattgtgc agttacaggc cgatccccgc ctgtttgaac tgtaccagtt tgacagaaaa
     1201 gtccttctcc agcttaaggc gattaatgcc ctgaagcgac gggagtccgc ccaggcactc
     1261 tacaccttta tagagagcct gccccgggat ccggcaccga tatcgctggc gcggctgcgt
     1321 gcacgcctca atctgaagtc tcctgtattt tcccagaacc agacggtcag acgggcaatg
     1381 gagcagttgc gcgagattgg atatcttgat tacacggaga tccagcgggg gcggacaaaa
     1441 ttcttctgta ttcactaccg gcgtccccgg ttaaaagcgc cgaatgacga gagtaaggaa
     1501 aatccgttgc aaccttcacc tgcggaaaaa gtcagtccgg agatggcgga gaagcttgcc
     1561 ctgcttgaga aactgggcat cacgctggat gacctggaaa aactcttcaa atcccgctga
     1621 acataaactg tagtcagtga agagcgctcc tttactgact acagcttata ttaaccggtg
     1681 cagtgagtgg tctgctcact gcagtttata ttctgtttcc tgcagtgctg tctgtagctg
     1741 agctgccatc tgcctgtccc ttacgtaagt gatcccgtaa cctgatgctg aggcattgct
     1801 cccttcataa aacatgactt actcactaca gcttatatac atgctccagc ttatgttatg
     1861 tctgttctgc tgaccacagc ttatataagg aagcgcgtat gccgtcacct caggggaggc
     1921 agtgtacgca ggatctccgc agcatcccgc ccgtcacctg tgaaaggcac tgccagcgtg
     1981 gcagccatat ccagtgcaaa cactctggta taaacctcca tcgaacgtgg atccctgtga
     2041 ccagccagtg cctggatgac tttccggggc tggcggtgat agagcatgtg catgatatag
     2101 ctgtgccgga aggtgtgtgg tgtgaccgga atcgaaaagt gtaccccgtc agcttcggcc
     2161 cgtctgacag cctgcttcag ccagttgcgc atggtttcgt cggtcacggc ccataatggt
     2221 tcacgacgac ggggccgggt ggtgatcatc cagctttcca tctgcctgac atagcttata
     2281 tctgtcagcg gcaccagtcg cacttcatct tttggcgggc gtccgcgtcg cgcacgcact
     2341 ttttcggaca ggatccgcac aaacggtctt actccattca ggtcaaatga ttccggcgtc
     2401 agcatccggg cttcgccaat acgcattccg gtattccaga gggtggcgaa cagcatatgg
     2461 tgacgctgat ccggcatata gaagagaagg gcactcactt ccggggccag caggtaggcc
     2521 ggtgtggccc ccgtggaagt ggccattctt ctcagggaga gcgctgttgc aaaatccacc
     2581 cccggcgcaa tgggtaacag ggagacgcgt tctggtgaat tctgcagggg aatgacattg
     2641 ttcatgagtt atttttcacg tagcacacgc actgtttatg gatacaggta ttctgacctg
     2701 aacgcccgga tccttccacg acaataaatc gcagcgcgcg gatccttttg tttgcttatc
     2761 acgcattatt gcgggtaaaa ccaaatacgt aaaggtatgt tttgcagcag ggatcccgta
     2821 ttaagccagt cgtggcgcgg gctgagggct ggtttgccgt ttttgggaga aatggggtaa
     2881 tgccagggca aagatgatcg caaggaaagg agaaaaatac acagagaggg gagttgcgct
     2941 acgtgaattc tggctaggta cacccctgta accctgccag ttttcacgca acgcaatgtg
     3001 gtggctgatt actgtcagtt gaaatgacgg ctggcatcct gatgctgact taatatacga
     3061 ataataacaa tttcagtatc agtctgcaga aaataaacca tatgccgttc aacgggtagt
     3121 gcgaatgtgt attccccagt tcaggagggg gagtaccgat attatgatta ctcataacct
     3181 gaaaaatgtc ggatatctga ttaatatatt tatcagccta ctcttcaccg aaatggtggt
     3241 acccgtaatg ctagatatcc tccagatcct gactggcttt aggtgtgagt ttaacggttt
     3301 tcaccggaag ccctcgcgcc agctttcact tttttcagaa acgcattttt ttcccacgac
     3361 acaggttcac cgctgctcaa gccttctgcc agtaaatccc gcaggacacc tggagacgtg
     3421 actctgcctg tttctctcga aggagacgaa gtgactcgcg gattacctca ctctgtgtac
     3481 gataatcacc tgattctatg agagattcta tgtactccca gagttcatct ccgagagcaa
     3541 ctgtcattgt tctggccata tcaagcctcg tgattgtaag tttaaatttt acatgcagtt
     3601 tattcgatac tcaaaggtgc ttccagtaca gaacatttgg gagaattggg gtaatgcctg
     3661 gaacagacag atacggagaa aaaccctgca gataacctta tacgacaact gaaggtgtct
     3721 gatgccatat tcttagctac ttctctgtct tcaggcggct tagtcacaac ataagaccga
     3781 tgcataataa gcatattttt tcatgttatg gtcttgttca tgcatgaact attatctatt
     3841 cagtcacttt taaagtttta tatcatactg catatgatat atatcatctc ctatattcag
     3901 actaaaaata ttatgacgat ggtcaaatga atttagtgaa aacgctacct aaaacaatat
     3961 gcttatgata taacttatca agaatatgcg acaatcttct tgaaaggtta cggagaagag
     4021 tcagataatg aagtgttata actcattcag cttttttatg ttctctttat agtaaaacca
     4081 ggagattaag atgaatcaga agtggaagac gttaattatt tcatta
//
LOCUS       DADXDL010000195         4122 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.195, whole genome shotgun sequence.
ACCESSION   DADXDL010000195 DADXDL010000000
VERSION     DADXDL010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4122)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4122)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4122
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.195"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..314
                     /locus_tag="IRB70_004796"
     CDS             <1..314
                     /locus_tag="IRB70_004796"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634596.1"
                     /translation="KKSWWRSTVNFIKNIKAKFSTKKDIKTVHEKEPELMTDPVTGLT
                     ITKQKWQEMSDRANVRTPQAAISYKVRQSDGEELKTPQNALQDVLEHAHRAGSAKRKM
                     R"
     gene            706..1569
                     /locus_tag="IRB70_004797"
     CDS             706..1569
                     /locus_tag="IRB70_004797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019843928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBC0634597.1"
                     /translation="MLIQEEYNRDKYINQIQSWTLCADSFENGTYRKPKEKALNKKYI
                     GYNNNYFINGFVFDIDQPSGAIAWDDCGLPKPNIIIQNTANGHAHLLYALKAPVCKTD
                     NARVKPLKLASLIQTGFTDRLKADRAYADVLMKNPINEAEWRTIWGNVEAYDLSYLSE
                     FIPDDIQEQKRLPSIGLGRNVNLFEDLRHYAYKSVLKFKEKSNYERWEKELVLKANGL
                     NIFCNSSNPLSYNEIKATARSVAKWTWRNFNKECFSSIQSCRGKKNAGKKKTKVRSKA
                     MLEQIMKADAE"
     gene            1575..1847
                     /locus_tag="IRB70_004798"
     CDS             1575..1847
                     /locus_tag="IRB70_004798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000125721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBC0634598.1"
                     /translation="MTAIRAAKRKNTAKDLAKKLGIHERTVRRYIALRRNDYESEAES
                     RRKTAYNLHFKDGLKWREVAEKMNTTEHAVKALAKRYKQIDQIERG"
     gene            complement(1863..2138)
                     /locus_tag="IRB70_004799"
     CDS             complement(1863..2138)
                     /locus_tag="IRB70_004799"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634599.1"
                     /translation="MSQKKEQKTAEKPTAGPLRKHRSRTEKIDDLKKQISDLRKAERE
                     ERQRARNEILLAVGKAVYEKAGKPKNIYGLQQYVESEEFKVDFKNDF"
     gene            complement(2271..2549)
                     /gene="traD"
                     /locus_tag="IRB70_004800"
     CDS             complement(2271..2549)
                     /gene="traD"
                     /locus_tag="IRB70_004800"
                     /inference="COORDINATES: protein motif:HMM:NF018152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraD"
                     /protein_id="HBC0634600.1"
                     /translation="MGSKKTLEQRMALAQDRLSKLKKEASEKERKAREHIKFKAGGEV
                     TKVFGLDYDPAVLVGFLAVYEKLKPEQKAQIKIDGENIIKSRLENADK"
     gene            complement(2528..2935)
                     /locus_tag="IRB70_004801"
     CDS             complement(2528..2935)
                     /locus_tag="IRB70_004801"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634601.1"
                     /translation="MNKKEIEIRLLILKNEIDIEDIKNYFINDEIEEGVFTDYLNLHY
                     AVDNAMHNNKKSLFERLVYLINKDRENEGKQKEVIADHDLVYLKLNNDIDINEFKRLF
                     SLQKNIPMNDFLNMFGYVVKIRREVEKWEVKKR"
     gene            3231..>4122
                     /locus_tag="IRB70_004802"
     CDS             3231..>4122
                     /locus_tag="IRB70_004802"
                     /inference="COORDINATES: protein motif:HMM:NF015354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HBC0634602.1"
                     /translation="MALYRLEMQNVSRSDGVSSVAKAAYRHRSVMIDERTGEMHGEKS
                     ANRDDLVYAEILAPKGTPDFLTKSSNDLWNFVEKTEKRKDARTAKEFKITLPCELTNE
                     QNIKLLKEYLTKNFVSKGIICDFVIHNDKDNRNPHAHVMITTREITPTGFGKKVRSWD
                     EEKTLHEWRKDWAKVQNQHLKKLGLKSRVSHRTLEEQKNIMIDLAKKAEDAKDFDKSI
                     LYLAKAIELDRPPMQNLSRKKWRSKEGQEQRKRDQAIRDKAREDARAVRVLRGVAVVD
                     VASFTVQPLQKKEQSKNNDFS"
BASE COUNT         1454 a          705 c          754 g         1209 t
ORIGIN      
        1 aaaaaaaatc gtggtggcgt tcgactgtta attttataaa aaatattaaa gctaagttct
       61 caactaaaaa agatattaaa accgttcacg aaaaagaacc tgagttaatg actgatccgg
      121 tgactggttt aacgattacc aagcaaaaat ggcaagagat gagtgacagg gcaaacgtaa
      181 ggactccaca ggctgcgatt tcgtacaagg taaggcaatc ggacggggaa gagctaaaaa
      241 cgcctcagaa tgcgttacag gacgttttag agcacgctca tagagcagga agcgcaaaaa
      301 ggaagatgcg ataatcagat cacggacagt acaaaatagg aaaggcagaa gcaatgaaca
      361 tagtattatg tatattatcc ttatggatca gttggttaat ggtagagccg cgaggctttg
      421 gaggtttttt agccgtactg atggtttcag tagtaatcga tatagtgctc atatgggtat
      481 acgcatacat aagagcttta ctcatcgtta ggcggtaaca caacacaggc agggcaagcc
      541 ctgccttaag cccaaaaaca gatcactatc tgatatggtt aaatcgcccg acttgacaca
      601 ctcgtaaaaa gtgttagaac ggtaacagaa aacaaaaacc cccgattttc gattgtttgg
      661 cgacagaaaa aatcgggggg catataaaaa aagggaaaac aaaatatgtt aatacaagaa
      721 gaatataaca gagataagta tataaatcaa attcaaagtt ggactttgtg tgcagatagt
      781 ttcgaaaacg gaacatacag aaagccaaaa gaaaaggcgt taaataaaaa atacattggc
      841 tataacaaca actattttat caatggtttt gtgtttgata tagatcagcc ttcaggtgcg
      901 attgcttggg atgattgcgg attacctaag cctaatataa tcattcaaaa tacggctaac
      961 ggtcatgctc atttgcttta tgctttaaaa gctcctgtat gtaaaacaga taatgcaaga
     1021 gtgaagccgc taaaacttgc aagccttatc cagactggat ttacagatag attaaaagca
     1081 gatcgtgcat atgctgatgt gctaatgaaa aacccaatca atgaagcaga atggcgtacg
     1141 atttggggta atgttgaagc ttatgatctc agctacctaa gcgagtttat acctgatgac
     1201 attcaagaac aaaaaagatt gccatctatt ggacttggac gcaatgttaa tttgtttgaa
     1261 gacctaagac attatgcata taaatccgtt ttaaaattta aagaaaaaag caactatgaa
     1321 agatgggaaa aagaacttgt attaaaagcc aatggattaa atatattctg caatagcagt
     1381 aatccattaa gttataatga gataaaagca acagcaagat cggtagctaa atggacgtgg
     1441 cgaaacttca ataaagaatg cttttcatct attcaatcat gcagaggaaa aaagaatgct
     1501 ggaaagaaaa aaacaaaagt tagaagcaaa gcaatgttag aacagatcat gaaagcagat
     1561 gcggagtaat tattatgaca gcaataagag cagctaaaag aaaaaataca gctaaagatt
     1621 tagctaaaaa actaggcatt catgaaagaa ctgtcagacg ttatattgca ttgcgtcgta
     1681 atgattatga gtcagaagct gaaagccgca gaaaaactgc atacaaccta cattttaaag
     1741 acggtttgaa atggcgtgaa gtagctgaaa aaatgaatac aacagaacat gcagttaaag
     1801 cattagccaa aagatataaa caaatagacc aaatcgaaag gggctaaaat gcccctttat
     1861 gtttagaaat cgtttttaaa atccacttta aattcttctg attctacata ttgctgcaag
     1921 ccatatatat tcttaggctt tcctgctttt tcgtaaacag ctttaccaac tgccaataat
     1981 atttcatttc tagccctttg gcgttcttct ctttctgctt ttctcaggtc actaatctgt
     2041 ttcttcaaat cgtctatttt ttcagttcta gatctgtgtt tacgaagtgg ccctgcagtt
     2101 ggtttttctg ctgttttttg ctcttttttt tgagacattt tttactctcc cggatgatat
     2161 gttttttaaa cataccacaa agccgggcta tcgtgaatac taacgcacaa gccccgccgc
     2221 tggcgggttc ttgcttgttc aacccttcca agtgtcagat tagaaatctg tcacttgtca
     2281 gcattttcta gacgtgattt tatgatgttt tcaccgtcaa tttttatctg tgctttttgc
     2341 tcaggtttca gcttttcata gacagccaga aaacctacca aaacagcagg atcataatcc
     2401 aagccaaaaa cttttgtaac ttctccgcca gctttaaatt ttatatgctc ccttgctttc
     2461 ctttccttct ctgacgcttc ttttttaagt ttagataatc tatcttgtgc aagtgccatt
     2521 ctttgttcta acgttttttt acttcccatt tttcaacctc tcttctaatt ttaacgacgt
     2581 agccaaacat gtttaaaaaa tcattcattg gtatgttttt ttgtaatgaa aataaccgct
     2641 taaactcatt aatatctata tcattattta gttttaaata tactaaatca tgatcagcta
     2701 taacttcctt ttgtttacct tcgttttcac gatctttatt tattaaataa actaaccttt
     2761 caaataatga ttttttattg ttatgcattg cattatcaac ggcgtaatgc agatttaaat
     2821 aatcagtaaa aacaccttct tctatttcat cgtttatgaa atagttttta atgtcttcaa
     2881 tatcgatctc attttttaaa atcaataatc ttatttctat ttctttttta ttcattttat
     2941 caccaaagta tactgcttga tttttattca atatcgtaac ttttaaatat tgtcaaattt
     3001 gactttaatt taatcagagt taatttatat gtatcagtga aagaaaaact atataggttt
     3061 tcattcctct tttagtttga gcgttagcga aaaataaaag ataaggaatg cccggttacg
     3121 cattgtaaac aatgccgggg tctgccgacg gctaaaacct gtttttctta cgaaaaacta
     3181 aaaccaaaac ccaaaacaaa aaataggggt tctcatgagg atataattat atggctttat
     3241 atagattaga aatgcagaac gttagtcgtt ctgatggtgt cagctcagtt gcaaaggcag
     3301 cttatcgtca tcgttcagtc atgatagatg aacgaacagg agaaatgcac ggcgagaaat
     3361 cagctaatcg tgacgatctc gtttatgctg aaatattagc accaaaaggc acgccggatt
     3421 ttcttactaa atcgagcaat gatctatgga actttgtcga aaaaacagag aagagaaaag
     3481 acgcaagaac agcaaaagaa tttaaaataa ctttgccttg tgaacttacc aatgaacaaa
     3541 atataaaact attgaaagaa tacttaacaa aaaactttgt tagtaaagga attatttgcg
     3601 actttgttat acataacgat aaagacaaca gaaacccaca cgctcacgtt atgattacga
     3661 caagagaaat aacgcctacg ggatttggta aaaaagtaag atcatgggat gaagaaaaaa
     3721 cccttcatga atggcgtaag gattgggcaa aagttcaaaa tcagcattta aaaaaattag
     3781 gcttaaaatc tcgtgttagt catagaacgc tagaagaaca aaaaaacata atgatcgatt
     3841 tagctaaaaa agcagaagat gcaaaagatt ttgacaagtc tattttatat ctagcaaaag
     3901 ctattgaact agatcgccca ccaatgcaga acttatcacg taaaaaatgg cgttctaaag
     3961 aggggcaaga acaacgcaaa cgtgaccaag cgatcagaga caaggcaaga gaagatgcaa
     4021 gggctgtcag ggtgttgagg ggtgttgcag ttgttgatgt tgcttcattc acagttcaac
     4081 cgctgcagaa aaaagagcag tcaaaaaata atgacttttc ag
//
LOCUS       DADXDL010000196         4069 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.196, whole genome shotgun sequence.
ACCESSION   DADXDL010000196 DADXDL010000000
VERSION     DADXDL010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4069)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4069)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4069
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.196"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(46..753)
                     /locus_tag="IRB70_004803"
     CDS             complement(46..753)
                     /locus_tag="IRB70_004803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001296720.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBC0634603.1"
                     /translation="MTSNPLIAYKSNALVEASYKLTLQEQRFLLLCISRLNSGTDVAS
                     PELQKTMTITAAEYFDSFPDMGRKNAEVQLQEAIDRLWDRSIILKDDEKREEFRWIQY
                     RAQYARGEGKAQITFSDAVMPYLTQLKGQFTRVVIKNISNLSRSYSIRIYEILQQFRS
                     TGERIIALDDFKSSLMLDGKYKDFKTLNRDLIQPCVDELNKKSDLAVTVETIKKGRTV
                     VALHFRFKEDKQIKMTI"
     gene            complement(1285..1539)
                     /locus_tag="IRB70_004804"
     CDS             complement(1285..1539)
                     /locus_tag="IRB70_004804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein"
                     /protein_id="HBC0634604.1"
                     /translation="MSRTLEQKIADAEARLQRLKAKSRSLDTAQKVIVGAALLAKVRK
                     PEEVQLRAWLLQFLKAEVTRQADVTRILPLINELEALPGQ"
     gene            1718..3877
                     /locus_tag="IRB70_004805"
     CDS             1718..3877
                     /locus_tag="IRB70_004805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HBC0634605.1"
                     /translation="MAIYHLSMKIISRNSGYSAVASAAYRSGSLMLDERTGLTHDYTR
                     KSGVAEAVILTPATAPAWCTNRAELWNAVEKAEHRKNSQLAREIELAIPRELPQDAAR
                     ETVLAFVRENFVSQGMIADVAFHHMDKTNPHAHIMLTTRAVGPAGFGGKVRDWNDRTH
                     AETWRASWADHANRALANAGYQEEIDHRSYERQGLEKTPGIHLGKSACAMETRGIETE
                     RGEQNRLINRLNLEIQISRTELRNSGLTEPARRVADLLNIVLPDNATSYTLRDIIEAL
                     PKDSNAAWKLTSNAMSMMADMQATRRRWEELNTERKEAMSHAASLKKSSPFSSGFSRI
                     PLMQWAAPEYRSEQGKIQSLSQQMEKLRQHYRKVEKQDIPASQTAFEKQWQQWGASGL
                     AALRVQLLKREEELRRKEQEDTERSRAERRAEQLRKNDNAVMDSGVLSAVVTGYGEAP
                     MPGNGEMTCYLLLHNRNGEYTLWGNELEKYRTRIFERVDLMRDRSGYICDRSEIGQHP
                     PLQRVYSSATFEQLLTQVCQTWPQYTRNLRQPKTWPESFCLGEDRQPAMPSLAARKVD
                     FTQGRLLPTLMPVMSSVDRETRQLQLLLVMGVDDSLGGVVRLNGTLYPAFAVPSADNS
                     QLVISALTDKGLRYAGYGVAVNHDADSHISPAPELMEFHLKTREAPLFAAVNTPEKQP
                     DHLFRSLGFNRTWDEWRREEDARTHATERRHDRGWSQ"
BASE COUNT         1060 a         1042 c          991 g          976 t
ORIGIN      
        1 aaaaaaaacg cagcagggag cgttttaggt gccttaaaat cgattctaga tcgtcatctt
       61 gatctgtttg tcttccttga agcgaaaatg cagggctaca accgtgcgcc cctttttgat
      121 cgtctcaacc gttacagcca ggtcgctttt tttgttcagt tcgtcaacac agggttgtat
      181 tagatccctg tttaacgttt tgaaatcttt atatttacca tcaagcatca gtgatgattt
      241 aaaatcatcg agggcgataa tacgttcccc agtactgcgg aattgctgga gaatttcgta
      301 tattcttatg ctgtaacttc ttgataaatt agaaatattt ttaatgacga ctctggtgaa
      361 ttgccccttc aactgtgtca gataaggcat taccgcgtca gaaaaagtga tttgtgcttt
      421 cccctctccc ctcgcgtact gtgcccgata ctgaatccag cggaactcct cgcgcttctc
      481 gtcgtccttg agaatgatcg acctgtccca caaacgatcg atcgcttcct gtagctgaac
      541 ctcggcattt ttccgcccca tatcagggaa tgaatcaaaa tattccgcag ctgtaatggt
      601 cattgtcttt tgcaattcag gtgaagctac gtcagtaccg gagttaagtc ggcttatgca
      661 gagcaataag aaacgctgtt cttgtaaagt tagcttgtaa ctggcctcaa ccagcgcatt
      721 ggacttatag gctatcagag ggtttgatgt cattttaacc accaggccaa aaatgaggtg
      781 aaataaaaac ctatcacctt tagcattggt gagcaattat attttcaccc cccattttcc
      841 tgtgaatatt accttaaatc tcctcacctt taccttaaat tacctcaccc aagcacctta
      901 aattatatca cctttacctt aaatcatatc acctatagcg ttgtaacatt ttgttttcta
      961 taaggaattt tggcgctaaa acaagtatta aaaacaagat cttaaaaaca agatctaaaa
     1021 acttaacgac gagcctgtgg ataacttgga gtgctgaaaa caaaaaacca ataaaaacaa
     1081 tgcgttgcaa aaaagcagaa ttgcaagttc cgaatacacc ccctccaacc ctgtggaaat
     1141 ccagtattca tgcgggttca gcgcatatca cctcccgaaa aaccgtgcgt atgtgctcaa
     1201 tcaggcgacg gattcacttc cgcttcctcg cccactcgct cgctaacgct cggtcgctgg
     1261 gactgcggcg agcggacgat acaatcactg tcctggcagc gcttccagct cgttaatcag
     1321 cggcagtatg cgcgtcacat cagcctgtcg tgtcacctct gccttcagga actggagtaa
     1381 ccaggcacgc aactgcacct cctccggctt tctgaccttt gccagcaatg ctgcacccac
     1441 aatgaccttc tgcgctgtgt ccagactcct gctcttcgcc ttcaggcgct gtaatctggc
     1501 ctcagcatca gcaatcttct gttcgagtgt tctgctcatg atgtaactcc gtgcgcgatg
     1561 aaaaatcgca ttttagcgcg tcactggtag tttaaaaact gagctggcat aatgcacgga
     1621 aaatcacgaa gtgcgcactt atacaatctc cactccgttt cgattgtgtg cgccctgcgg
     1681 ggctgaaaga aaaccacaaa aaggcattac ggcagaaatg gcgatttatc atctcagcat
     1741 gaaaatcatc tccagaaaca gcggctacag cgccgttgct tctgctgcct atcgttccgg
     1801 ttcactgatg cttgatgagc gtaccggact gactcacgac tacacccgca aaagcggtgt
     1861 ggctgaagct gtgattctga ctcccgcgac agcccctgcc tggtgtacga accgtgccga
     1921 actctggaat gccgttgaga aggccgaaca ccggaagaac tcacaacttg cgcgggaaat
     1981 tgaactcgcc atcccccgcg aactgccgca ggatgccgca cgggaaaccg ttctcgcctt
     2041 tgtcagagaa aactttgtca gtcagggcat gattgctgat gtggcgttcc atcacatgga
     2101 taaaacaaat ccccatgcgc acatcatgct gaccacgaga gctgtcggac ctgctggatt
     2161 cggtggaaag gtcagggact ggaacgaccg gacacatgcc gagacgtggc gtgcatcatg
     2221 ggctgaccat gcgaacaggg cactggcgaa cgccggttat caggaagaga tagaccatcg
     2281 ttcatacgag cgacaggggc ttgagaaaac gcctggtatt cacctcggaa agtctgcctg
     2341 tgcgatggaa acacgcggta tcgaaacaga acgcggcgaa cagaatcgtc tgattaacag
     2401 acttaacctg gaaatacaga tttcccgtac cgaactcaga aacagcgggc tgacagagcc
     2461 tgcccgccgt gtggctgacc ttctgaatat cgtgcttcct gacaacgcaa cttcgtacac
     2521 actacgtgac atcatcgaag cgttgccgaa ggacagtaat gcggcatgga aactcaccag
     2581 taatgccatg tcgatgatgg cagatatgca ggcgacgcgc agacgctggg aagagctgaa
     2641 caccgaacga aaggaagcga tgagccatgc tgccagcctg aaaaaatcat cgccgttttc
     2701 gtccggtttt tcccgtattc ccctgatgca atgggcggca ccggaatacc gtagcgaaca
     2761 gggaaaaatc cagtcgctga gccagcaaat ggaaaaattg cgacagcatt accggaaggt
     2821 ggagaaacag gacattcccg cgagtcagac ggcatttgaa aaacagtggc agcagtgggg
     2881 ggcatccggc cttgcagctc tcagagtcca gttgcttaaa cgtgaagagg aattgcgccg
     2941 gaaggagcag gaggatacag aacgtagtcg cgcggagcga cgagcggaac agctcaggaa
     3001 aaatgacaat gccgttatgg attcaggggt actgagcgca gtcgttacgg ggtatggcga
     3061 ggcccccatg cctggtaacg gggaaatgac ctgttacctt ctgcttcaca accggaacgg
     3121 agaatacacg ctctggggga acgagctgga gaaataccgc accagaatct ttgagcgtgt
     3181 tgatttaatg cgtgacagga gtggttatat ctgtgaccga agcgaaatcg gtcaacatcc
     3241 accactgcaa cgtgtttatt cctctgcgac ctttgagcaa cttctgacgc aggtttgcca
     3301 gacatggccg caatataccc gcaatctccg ccagccgaag acatggccgg agtctttctg
     3361 tcttggagaa gaccgccagc cagccatgcc atcactggca gcaaggaagg tggattttac
     3421 gcagggacgt ctgctaccga cgctgatgcc ggtaatgagt tctgtcgacc gggaaacccg
     3481 ccagcttcag cttttgctgg tcatgggcgt ggatgactct ctgggcggtg ttgtccggct
     3541 taatggtacg ctgtatcccg cgtttgccgt tccctcagcc gataacagcc agctggtcat
     3601 cagtgcactg accgataagg ggttacggta tgcagggtat ggtgttgccg taaatcacga
     3661 tgcagacagc cacatatcac ctgcgccgga acttatggag tttcatctga aaacccgtga
     3721 ggcaccgctt tttgctgccg tcaacacacc agaaaaacag ccggatcatc tgttccgctc
     3781 gctgggtttt aatcgtacct gggacgaatg gcggcgcgag gaagatgcac gaacacacgc
     3841 caccgagagg agacatgatc gcggttggtc acagtgaatg tgaacaatat tttgttttgt
     3901 ttaacatcgt gttatgttcg tcgatgttca tcgacaggga tgaatgcaag aagcacacac
     3961 agcatagttt tgtttttccg cccccaaaaa ttgggggttc ttttttcgct gcattagagc
     4021 gcttttgacg caatttttca cttcaatagt accttcgcac tactaacac
//
LOCUS       DADXDL010000197         4050 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.197, whole genome shotgun sequence.
ACCESSION   DADXDL010000197 DADXDL010000000
VERSION     DADXDL010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 4050)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4050)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4050
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.197"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            142..735
                     /gene="tetC"
                     /locus_tag="IRB70_004806"
     CDS             142..735
                     /gene="tetC"
                     /locus_tag="IRB70_004806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000428546.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracyline resistance-associated
                     transcriptional repressor TetC"
                     /protein_id="HBC0634606.1"
                     /translation="MENKNHQQENFKSTYQSLVNSARILFVEKGYQAVSIDEISGKAL
                     VTKGAFYHHFKNKKQLLSACYKQQLIMIDAYITTKTDLTNGWSALESIFEHYLDYIID
                     NNKNLIPIQEVMPIIGWNELEKISLEYITGKVNAIVSKLIQENQLKAYDDDVLKNLLN
                     GWFMHIAIHAKNLKELADKKGQFIAIYRGFLLSLKDK"
     gene            complement(848..2053)
                     /gene="tet(B)"
                     /locus_tag="IRB70_004807"
     CDS             complement(848..2053)
                     /gene="tet(B)"
                     /locus_tag="IRB70_004807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HBC0634607.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
     gene            2135..2758
                     /gene="tetR(B)"
                     /locus_tag="IRB70_004808"
     CDS             2135..2758
                     /gene="tetR(B)"
                     /locus_tag="IRB70_004808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HBC0634608.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            complement(2736..3422)
                     /locus_tag="IRB70_004809"
     CDS             complement(2736..3422)
                     /locus_tag="IRB70_004809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBC0634609.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(3430..3816)
                     /locus_tag="IRB70_004810"
     CDS             complement(3430..3816)
                     /locus_tag="IRB70_004810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000460649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid-binding protein"
                     /protein_id="HBC0634610.1"
                     /translation="MFDVHVVLDNQIGQLALLGKTLGNKGIGLEGGGIFTVGDECHAH
                     FLVEQGKEAKIALEQAGLLVLAIRTPLIRKLKQEKPGELGEIARVLAENNINILVQYS
                     DHANQLILITDNDSMAASVTLPWAIK"
     gene            complement(3809..4024)
                     /locus_tag="IRB70_004811"
     CDS             complement(3809..4024)
                     /locus_tag="IRB70_004811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001384468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBC0634611.1"
                     /translation="MSIERFQSLATEGKMLSLSWWENEYAVLQWKNHVLHAKAQQEGR
                     ESIFDFYKISIAHITREYSFKKDKDNV"
BASE COUNT         1332 a          853 c          730 g         1135 t
ORIGIN      
        1 taattggatg ttattagctt tattttgata gcgagaatgc tgttcaatat acataaaata
       61 acctaaatgt tcttaagatt gtcacgacca catcatcatg ataccataaa catactgacg
      121 gtatgttatt ttaaatctat catggaaaat aaaaatcatc aacaagaaaa ttttaagagt
      181 acctatcaat cactggttaa ctcagcacga atattgtttg ttgaaaaagg ctatcaagct
      241 gtttcaatag atgagatctc gggaaaagcg ttggtgacca aaggtgcctt ttatcatcac
      301 tttaaaaata aaaaacaatt actcagtgcc tgttataagc agcaattaat tatgattgat
      361 gcctacatca caacaaaaac tgatttaaca aatggttggt ctgccttaga aagtatattt
      421 gaacattatc ttgattatat tattgataat aataaaaacc ttatccctat ccaagaagtg
      481 atgcctatca ttggttggaa tgaacttgaa aaaattagcc ttgaatacat tactggtaag
      541 gtaaacgcca ttgtcagcaa attgatccaa gagaaccaac ttaaagctta tgatgatgat
      601 gtgcttaaaa acttactcaa tggctggttt atgcatatcg caatacatgc gaaaaaccta
      661 aaagagcttg ccgataaaaa aggccaattt attgctattt accgcggctt tttattgagc
      721 ttgaaagata aataaaatag ataggtttta tttgaagcta aatcttcttt atcgtaaaaa
      781 atgccctctt gggttatcaa gagggtcatt atatttcgcg gaataacatc atttggtgac
      841 gaaataacta agcacttgtc tcctgtttac tcccctgagc ttgaggggtt aacatgaagg
      901 tcatcgatag caggataata atacagtaaa acgctaaacc aataatccaa atccagccat
      961 cccaaattgg tagtgaatga ttataaataa cagcaaacag taatgggcca ataacaccgg
     1021 ttgcattggt aaggctcacc aataatccct gtaaagcacc ttgctgatga ctctttgttt
     1081 ggatagacat cactccctgt aatgcaggta aagcgatccc accaccagcc aataaaatta
     1141 aaacagggaa aactaaccaa ccttcagata taaacgctaa aaaggcaaat gcactactat
     1201 ctgcaataaa tccgagcagt actgccgttt tttcgcccca tttagtggct attcttcctg
     1261 ccacaaaggc ttggaatact gagtgtaaaa gaccaagacc cgctaatgaa aagccaacca
     1321 tcatgctatt ccatccaaaa cgattttcgg taaatagcac ccacaccgtt gcgggaattt
     1381 ggcctatcaa ttgcgctgaa aaataaataa tcaacaaaat gggcatcgtt ttaaataaag
     1441 tgatgtatac cgaattcgat tgcgtctcaa cccctacttc ggtatctgta ttatcacgtg
     1501 tatttttggt ttcacggaac caaaacataa ccacaaggaa agcgacaata tttagcaacg
     1561 cagcgataaa aaagggacta tgcggtgaaa tctctcctgc aaaaccacca ataataggcc
     1621 ccgctattaa accaagccca aaacttgccc ctaaccaacc gaaccacttc acgcgttgag
     1681 aagctgaggt ggtatcggca atgaccgatg ccgcgacagc cccagtagct cctgtgatcc
     1741 ctgaaagcaa acggcctaaa tacagcatcc aaagcgcact tgaaaaagcc agcaataagt
     1801 aatccagcga tgcgcctatt aatgacaaca acagcactgg gcgccgacca aatcggtcag
     1861 acatttttcc aagccaagga gcaaagataa cctgcattaa cgcataaagt gcaagcaata
     1921 cgccaaagtg gttagcgata tcttccgaag caataaattc acgtaataac gttggcaaga
     1981 ctggcatgat aaggccaatc cccatggcat cgagtaacgt aattaccaat gcgatctttg
     2041 tcgaactatt catttcactt ttctctatca ctgataggga gtggtaaaat aactctatca
     2101 atgatagagt gtcaacaaaa attaggaatt aatgatgtct agattagata aaagtaaagt
     2161 gattaacagc gcattagagc tgcttaatga ggtcggaatc gaaggtttaa caacccgtaa
     2221 actcgcccag aagctaggtg tagagcagcc tacattgtat tggcatgtaa aaaataagcg
     2281 ggctttgctc gacgccttag ccattgagat gttagatagg caccatactc acttttgccc
     2341 tttagaaggg gaaagctggc aagatttttt acgtaataac gctaaaagtt ttagatgtgc
     2401 tttactaagt catcgcgatg gagcaaaagt acatttaggt acacggccta cagaaaaaca
     2461 gtatgaaact ctcgaaaatc aattagcctt tttatgccaa caaggttttt cactagagaa
     2521 tgcattatat gcactcagcg ctgtggggca ttttacttta ggttgcgtat tggaagatca
     2581 agagcatcaa gtcgctaaag aagaaaggga aacacctact actgatagta tgccgccatt
     2641 attacgacaa gctatcgaat tatttgatca ccaaggtgca gagccagcct tcttattcgg
     2701 ccttgaattg atcatatgcg gattagaaaa acaacttaaa tgtgaaagtg ggtcttaaaa
     2761 gcagcataac ctttttccgt gatggtaact tcacggtaac caagatgtcg agttaaccac
     2821 cctttagatt cataaagcga aaataatgcg gctccaacgt acccacctaa atggaaacgg
     2881 cgttcactcc aatctaaaca cgcacaacag attttacgtg aatgtttgga aggaacgtca
     2941 attcccattt catgaaaata ttgaatacca cttaatgtga tcattgaacc attttcagtg
     3001 atccattgct gttgacaaag ggaatcatag atcttaacgg caacttcgcc agctaaatga
     3061 tcatagcaag tacgtgcttt tcgtaaatgc actggcgtgg aaactttggc atgtacgcca
     3121 tggtttaagg agatccccat catactttcc atcaattcag caatatcttt tcctgctagc
     3181 cgaaaataac gatgcttgcc ttgagctact actgtgatta gctggcaatc taataattta
     3241 gataaatgac tgctcgccgt tgaagctgat atattcgcca cagaacttag ctcagtggcc
     3301 gtccaagctc gcccatccat caaagcactg agtattttaa ctcgtgaaat gtcagacata
     3361 gccgccccta tcgcggctat tgaggactca aaggtaacct cttttcgtat taaattagcc
     3421 atcgcaagtt cactttattg cccaagggag cgtaacagat gcagccatac tatcattgtc
     3481 cgttattaat atcagttggt tagcatggtc actgtattgc actaaaatat taatgttatt
     3541 ctccgccaat actcgtgcta tttcgccaag ttcccccggt ttttcctgtt ttaacttacg
     3601 aattaatggt gtccggatcg caagtactaa cagtccagct tgctctagcg ctattttagc
     3661 ttcctttcct tgttcaacaa gaaaatgagc atggcattca tcaccaaccg taaatatccc
     3721 tcccccttcc aatccaatac ctttattacc taatgttttt cctagtaatg ctaattgtcc
     3781 tatttgatta tctaaaacaa cgtgaacatc aaacattatc cttgtccttt ttaaatgaat
     3841 attcgcgagt aatatgagca atactaattt tgtaaaaatc aaatattgac tctcgccctt
     3901 cttgttgagc tttcgcatgt aaaacatgat ttttccattg cagaactgcg tattcgtttt
     3961 cccaccaaga tagcgataac atttttcctt ctgtagctag actttgaaaa cgttcaattg
     4021 aaataaaacc agctacatga cttaatagtg
//
LOCUS       DADXDL010000198         3977 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.198, whole genome shotgun sequence.
ACCESSION   DADXDL010000198 DADXDL010000000
VERSION     DADXDL010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3977)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3977)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3977
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.198"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            98..799
                     /locus_tag="IRB70_004812"
     CDS             98..799
                     /locus_tag="IRB70_004812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001281399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBC0634612.1"
                     /translation="MSDLIAYKSNALIEASYKLTLQEQRFLLVCISRLKSGEDSPSPD
                     EQKTMTITAAEFHDAFPDMGRQHAEARLKEAIDRLWDRSVIIKNEEKREEFRWVQYRA
                     QYFKGEAKVDITFSDAIMPYLTQLKGQFTRVVVKNVSSLSSTYSIRIYELLQQFRSTG
                     DRTIAIDDFRTMLAVEDKYQQFKDLNKMIIKPAIAELNEKSDLVVTVETIKKGRTVVA
                     LHFRFKEDKQIKMTI"
     gene            complement(1047..3194)
                     /locus_tag="IRB70_004813"
     CDS             complement(1047..3194)
                     /locus_tag="IRB70_004813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016240513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobA/MobL family protein"
                     /protein_id="HBC0634613.1"
                     /translation="MAIYHLSMKIISRSSGYSAVASAAYRSGSLMLDERTGLTHDYTR
                     KSGVAEAVILTPATAPAWCTNRAELWNAVEKAERRKNSQLAREIELAIPHELPQDAAR
                     ETVLAFVRENFVSQGMIADVAFHHMDKTNPHAHIMLTTRAIGPAGFSGKVRDWNDRTH
                     AETWRASWADHANRALANAGYQEEIDHRSYERQGLEKTPGIHLGKSACAMETRGIETE
                     RGEQNRLINRLNLEIQISRTELRNGGLTEPARRVADLLNIGLPDNATSYTLRDIIEAL
                     PKDSNSAWKLTSNAMSMMADMQATRRRWEELNTERKEAMSHAASLKKSSPFSSGFSRI
                     PLMQWAAPEYRSEQGKIQSLSQQMEKLRQHYRKVEKQDIPASQMAFEKQWQQWGESGL
                     AALRAQLLKREEELRRKEQEDTERSRAEQLRKNDNAVMDSGVLRAVVTGYGEAPMPGN
                     GEMTCYLLLHNRNGEYTLWGNELEKYRTRIFESVDLMRDRSGYICDRSEIGQRPPLQR
                     VYSSATFEQLLTQVCQTWPQHTRNLRQPKTWPESFCLGEDRQPAMPSPAARKVDFMQG
                     RLPPTLMPVMSSVDRETRQLQLLLVMGVDDSLGGVIRLNGTLYPAFAVPSADNRHLVI
                     SALTDKGLRYAGYGVAVNHDADSHISPAPELMQFHLKTREAPLFAAVNTPEKQPDHLF
                     RSLGFNRTWEEWQREEDARTHTTERRHDRGWSQ"
     gene            3373..3627
                     /locus_tag="IRB70_004814"
     CDS             3373..3627
                     /locus_tag="IRB70_004814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000091744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein"
                     /protein_id="HBC0634614.1"
                     /translation="MSRTLEQKIADAEARLQRLKAKSRSLDTAQKVVVGAALLAKVRK
                     PEEVQLRAWLLQFLKAEVTRQADVTRILPLINELEALPEQ"
BASE COUNT          944 a         1024 c         1021 g          988 t
ORIGIN      
        1 aatccacaga aaaagggggt tgcaaaaaaa aaacttccac ccatatgata agtggcgtac
       61 agtaaaaaaa cgccaccaat agcaacgagc aagcgaaatg tcagatctga tagcttacaa
      121 atcaaacgcc cttatcgagg caagctacaa gctcactttg caggaacagc gcttcctgct
      181 ggtctgtatc agccgcctaa aatccggaga agattcccct tcgccggatg aacaaaaaac
      241 catgaccatc acggctgcag agtttcatga tgcctttcct gacatgggac ggcagcacgc
      301 tgaagctagg ctcaaggaag cgatagatcg cctctgggac aggtcagtaa tcatcaagaa
      361 cgaggaaaaa cgagaagagt tccgctgggt gcagtaccgg gcgcagtatt tcaaaggtga
      421 ggcgaaagta gatatcacct tctccgatgc catcatgccg tatctgacac agctcaaggg
      481 gcagtttacg cgggtagtcg tgaagaacgt ctccagcctt tccagcacct acagcatccg
      541 catttacgag ctgctccagc agttccgcag caccggtgac agaacgatag ctatcgatga
      601 tttccgaacc atgcttgccg ttgaagataa atatcaacaa ttcaaagact tgaataagat
      661 gataatcaag ccagccatcg ccgaactgaa cgaaaaaagc gatctggttg taactgttga
      721 gacgatcaaa aaggggcgca cggttgtagc cctgcatttt cgcttcaagg aagacaaaca
      781 gatcaagatg acgatctaaa atcgatttta aggcacctaa aacgctccct gctgcgtttt
      841 ttttgtgtta gtagtgcgaa ggtactattg aagtgaaaaa ttgcgtcaaa aacgctctga
      901 tgcagcgaaa aaagaccccc caatttttgg gggcggaaaa acaaaactat gcttgcgtta
      961 tgtgagtgtg cttcttgcat tcatccctgt cgatgaacat cgacgaacat aacacgatgt
     1021 taaacaaaac aaaatattgt tcacattcac tgtgaccaac cgcgatcatg tctcctctcg
     1081 gtggtgtgtg ttcgtgcatc ttcctcgcgc tgccattcct cccaggtacg attaaaaccc
     1141 agcgagcgga acagatgatc cggctgtttt tctggtgtgt tgacggcagc aaaaagcggt
     1201 gcctcacggg ttttcagatg aaactgcatc agttctggtg caggtgatat gtggctgtct
     1261 gcatcgtgat ttacggcaac accataccct gcataccgta accccttatc ggtcagcgca
     1321 ctgatgacca gatgcctgtt atcggctgag ggaacggcaa acgcgggata cagcgtacca
     1381 ttaagccgga taacaccgcc cagagagtca tccacgccca tgaccagcaa aagctgaagc
     1441 tggcgggttt cccggtcgac agaactcatg accggcatca gcgtcggtgg cagacgtccc
     1501 tgcataaaat ccaccttcct tgccgctggt gatggcatgg ctggctggcg gtcttctcca
     1561 agacagaaag actccggcca tgtcttcggc tggcggagat tgcgggtatg ttgcggccat
     1621 gtctggcaaa cctgcgtcag cagttgctca aaggttgcag aggaataaac acgttgcagt
     1681 ggcggacgtt ggccgatttc gcttcggtca cagatataac cactcctgtc acgcattaaa
     1741 tcaacactct caaagattct ggtgcggtat ttctccagct cgttccccca gagcgtatat
     1801 tctccgttcc ggttgtgaag cagaaggtaa caggtcattt ccccgttacc aggcatggga
     1861 gcctcgccat accccgtaac gactgctctc agcacccctg aatccataac ggcattgtca
     1921 tttttcctga gctgctccgc gcgactacgt tcagtatctt cctgttcctt ccggcgcaat
     1981 tcctcttcac gtttaagcaa ctgggctctg agagctgcaa ggccggattc cccccactgc
     2041 tgccactgtt tttcaaatgc catctgactc gcgggaatgt cctgtttctc caccttccgg
     2101 taatgctgtc gtaatttttc catttgctgg ctcagagact ggatttttcc ctgctcacta
     2161 cggtattccg gtgccgccca ttgcatcagg ggaatacggg aaaaaccgga cgaaaacggc
     2221 gatgattttt tcaggctggc agcatggctc atcgcttcct ttcgttcggt gttcagctct
     2281 tcccagcgtc tgcgcgtcgc ctgcatatct gccatcatcg acatggcatt actggtgagt
     2341 ttccatgccg agttactgtc cttcggcaac gcttcgataa tgtcacgtag tgtgtacgaa
     2401 gttgcgttgt caggaagccc gatattcaga aggtcagcca cacggcgggc aggctctgtc
     2461 agccctccgt tcctgagttc ggtgcgggaa atctgtattt ccaggttaag cctgttaatc
     2521 agacgattct gttcgccgcg ttctgtttcg ataccgcgtg tttccatcgc acaggcagac
     2581 tttccgaggt gaataccagg cgttttctca agcccctgtc gctcgtatga acgatggtct
     2641 atctcttcct gataaccggc gttcgccagt gccctgtttg catggtcagc ccatgatgcc
     2701 cgccacgtct cggcatgtgt ccggtcgttc cagtccctga cctttccgct gaacccagca
     2761 ggtccgatag ccctcgtggt cagcatgatg tgcgcatggg gatttgtttt atccatgtga
     2821 tggaacgcca catcagcaat catgccctga ctgacaaagt tttctctgac aaaggcgaga
     2881 acggtttccc gtgcggcatc ctgcggcagt tcgtggggga tggcgagttc aatttcccgc
     2941 gcaagttgtg agttcttccg gcgttcggcc ttctcaacgg cattccagag ttcggcacgg
     3001 ttcgtacacc aggcaggggc ggtggcgggg gtcagaatca cagcctcagc cacaccgctt
     3061 ttgcgggtgt agtcgtgagt cagtccggta cgctcatcaa gcatcagtga accggaacga
     3121 taggcagcgg aagctacggc gctgtagccg ctgcttctgg agataatttt catgctgaga
     3181 tgataaatcg ccatttctgc cgtaatgcct ttttgtagtt ttctttcagc cccgcagggc
     3241 gcacacaatc gaaacggagt ggagattgta taagtgcgca cttcgtgatt tgccgtgcat
     3301 tatgccagct cagtttttaa actaccagtg acgcgctaaa atgcgatttt tcatcgcgca
     3361 cggagttaca tcatgagcag aacgctcgaa cagaagattg ctgatgctga ggcgagatta
     3421 cagcgcctga aggcgaagag ccggagcctg gacacagcgc agaaggttgt tgtgggtgct
     3481 gcattgctgg caaaggtcag aaagccggag gaggtgcagt tgcgtgcctg gttactccag
     3541 ttcctgaagg cagaggtgac acgacaggct gatgtgacgc gcatactgcc gctgattaac
     3601 gagctggagg cgctgccaga acagtgattg tatcgtccgc tcgccgcagc cccagcgacc
     3661 gagcgttagc gagcgagtgg gcgaggaagc ggaagtgaat cagtcgccag gttgagcaca
     3721 tacgcacggt ttttcggcag gtgatatgcg ctgaacccgc atgaatactg ggtttccaca
     3781 gggttggagg gggtgtattc gaaacttgca attctgcttt attgcaacgc attgttttta
     3841 ttggtttttt gttttcagca ccccaagtta tccacaggct cgccgttaag tttttaagat
     3901 cttattttta gatctttttt tttaaaacct ttttaggtct tgtaacacca tgattttaaa
     3961 gatgttctgg caagata
//
LOCUS       DADXDL010000199         3959 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.199, whole genome shotgun sequence.
ACCESSION   DADXDL010000199 DADXDL010000000
VERSION     DADXDL010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3959
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.199"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            244..1653
                     /locus_tag="IRB70_004815"
     CDS             244..1653
                     /locus_tag="IRB70_004815"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634615.1"
                     /translation="MFKPENVGSIPNEEIVKFVSMLEENDDIEKVSTDINNAHKAYIY
                     NKALEVINEENIFEIMSLIPQPFLTRKSEKEADILSVIYNKFLENTEIPGALPVFSFF
                     SFLSAFCVKNNITYSIPLSEDKNPLDTWITVLAPSGSAKTFSNAQINKMIPKTPDGKK
                     VIEQNFSRPNGAAKFIQELSDLPLTKDGESQYGFWIEDEAAQMFKQIEKIGSPLSEIK
                     EYLLKAYDHDVLTRKTKTETVETKNIILTLFFINTFESYVNNISQESMTDGLMRRFNL
                     VYSEKDGRDFTDYSIYNVNKIRDEVLTDKMLEFFFSINPDQHFTFSVECLELYQKYFK
                     IYWHRKYKTILPGKENFYRTYMMQSWKFAIFYHFILGKEGNVIDEECLVYGMKISLLF
                     AESMKKFFDFKTKPQHIEKAKTDLDKYVNYLNANTEIKMRDFTRKFTVKKAEALTILK
                     AIKQARLVSNHILFKEIKE"
     gene            2041..2391
                     /gene="mobC"
                     /locus_tag="IRB70_004816"
     CDS             2041..2391
                     /gene="mobC"
                     /locus_tag="IRB70_004816"
                     /inference="COORDINATES: protein motif:HMM:NF017524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBC0634616.1"
                     /translation="MKNYKDRYQRKHSITLCFNDEEFAQVEELASMLKKPRATAVRDL
                     ILNKDFKLKKEISKNKTGDVYFELHKIGVNINQIARAINTDIDKFISYEFAEDFLNLF
                     EEITNEIEEIKRRI"
     gene            2393..3796
                     /locus_tag="IRB70_004817"
     CDS             2393..3796
                     /locus_tag="IRB70_004817"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634617.1"
                     /translation="MYHKIIGGKKSKGQRNINKSIEYLLREKNPEQQKDIKILSTTTK
                     QDLINFENYILDKNKSNPYVCGVLSFEEKTISEELKTKIITEFEDVLFTGIQPENRPP
                     VLWVEHNDKGRVELNYLTFNSLQDRRSYTVYLDKRDRGLVNDYSEIINYENNLSSPFE
                     EKENKNTLVNTPKTNIPKDKKEFIEKLNTEILALIINEELENREEAIKHIESIQGVKI
                     NRVRKNQISIKCDFFNDDKPIVLKGDIYEEGRNYSDYRKEYDSKPKRDPQLVEAKLTE
                     LKRSFSGRIEKRKIRNRERFKISQSKNKSENTKDIERENINIEYRFINNNIDFTVNNN
                     GFTNNNDSLFAMEKLKNESINSEHKTKTTTEETARSERKRDIEQINQQQQFINRRVEE
                     IRRTQQQIGKSLDSTEERIGRNRRALYSIVSTFRRYIRTFSAYSRKNQNKRYFEEKRR
                     IEEEKQFTQRRRKKFIY"
BASE COUNT         1690 a          525 c          623 g         1121 t
ORIGIN      
        1 aaaaaaaaga caaatatatt tctaaatgtt aataaatcaa aatgtcagaa atttgtcaga
       61 gttgaaaaac tgacaaagaa atgtagataa aacaacagta taagccactt tgtcagatgt
      121 cagactgtca gaaccaaacc cctaacactg tcagattttt ttgaagtttt tttctgactt
      181 tttattgaca gagtgttttt tgtactttat atatatatta taattaatat aggagaattt
      241 attatgttta aacctgaaaa cgtaggatct ataccaaatg aagaaatagt aaaatttgta
      301 tctatgcttg aagaaaatga tgatattgaa aaagtatcaa ccgatataaa caatgcacat
      361 aaagcttata tttacaataa agcactggag gttataaacg aggaaaatat atttgaaata
      421 atgtcattaa tacctcagcc atttttaaca agaaaaagcg aaaaagaggc tgatatatta
      481 tcagtaatat ataataagtt tttagaaaat acagaaatac ccggagcatt accagtattt
      541 tcatttttta gttttttaag tgctttttgt gtgaaaaata atatcacata ttcgatccca
      601 ttatctgaag ataaaaaccc attagataca tggatcacgg ttcttgcacc gtcaggttct
      661 gcgaaaacct tttctaatgc tcaaataaat aaaatgatac ctaaaacccc agacggtaaa
      721 aaagttattg agcagaattt ctcaagaccg aacggagccg caaaattcat tcaagaactg
      781 tcagatcttc cactgacaaa agacggtgaa tcacagtatg gtttttggat agaagacgaa
      841 gcggctcaaa tgtttaagca gattgaaaaa atcggctctc cgttgtcaga aataaaagaa
      901 tatttattaa aagcatatga tcacgatgtt ttgaccagaa aaacaaaaac agaaacagta
      961 gaaacaaaaa atatcattct aactttattt tttataaata cttttgaaag ttatgtaaat
     1021 aatatatctc aagagtcaat gactgatggt ttaatgcgaa gatttaacct tgtatatagt
     1081 gaaaaagacg gtagagattt tacagattac tcaatatata atgtaaataa aattagagat
     1141 gaagtactca cagataaaat gcttgagttt ttcttctcaa taaatcccga tcaacatttt
     1201 acattttcag tagaatgttt agagctttac cagaaatatt ttaaaatata ttggcatagg
     1261 aaatacaaaa ctattttacc gggtaaagaa aatttttaca gaacttatat gatgcaatct
     1321 tggaagtttg ctatatttta tcatttcatt cttggcaaag aaggaaatgt aatagacgaa
     1381 gaatgtttag tttatggaat gaaaatatca ttattgtttg ctgaaagtat gaaaaagttt
     1441 ttcgacttta aaactaaacc acagcacatt gaaaaagcaa aaacagattt agataaatat
     1501 gtaaactatt taaatgctaa tacagaaatt aaaatgcgag attttactcg taaatttaca
     1561 gtaaaaaaag cagaagcatt aacaattcta aaagcaatta aacaagcaag attggtttct
     1621 aaccatattt tatttaaaga aataaaagaa taaaaccgtc ctaccggaca ggtcaaccct
     1681 tcaaaaataa taaagcccta taagggcttt tttattttct cagcgttttc ataaaaaaat
     1741 agtggttatt ttacatactg ctattgacat tatttttaaa tatattaatt aatatataag
     1801 ggaaaattat ataacagcaa gctcagacaa tacttcgtat tgtcgcttgt gaggggttcc
     1861 cccttcaatc cccttaaaac ccaaaaccca aggagttaga tatgattgaa tattgcgagt
     1921 attgcggttg tgataccgaa cacaccatag accaaacgga cgaagtaaat gacaaggggc
     1981 aggagtatgt gtacatatcc tgtcttgaat gtcgttctgg ttacttagag ttaaacgctg
     2041 atgaaaaact ataaggatag ataccaaaga aagcacagta tcacactgtg cttcaatgac
     2101 gaggaatttg cacaggttga agaactggct tctatgttga aaaaacccag agcaacagcc
     2161 gttagagatc ttattctcaa taaagatttc aaactcaaaa aagaaatatc aaaaaataaa
     2221 actggcgatg tatattttga actccataaa ataggagtaa acattaacca gattgcaaga
     2281 gcaataaata ctgatattga taaatttatt tcctatgagt ttgcagaaga ttttttaaat
     2341 ttgtttgagg aaataacaaa tgagatagaa gaaataaaaa ggagaatata atatgtatca
     2401 taaaataata ggaggtaaaa aaagcaaagg gcaaagaaat ataaataaaa gcattgaata
     2461 tttattgaga gagaaaaacc cagaacaaca gaaagacata aaaatattat caacaaccac
     2521 aaaacaagac ctaatcaatt ttgaaaatta tattttagat aaaaacaaat caaaccccta
     2581 tgtttgtggt gttttatctt ttgaagaaaa aacaatatcg gaagaattaa aaacaaaaat
     2641 aataacagag tttgaagatg tattatttac agggattcaa ccagaaaaca ggccccctgt
     2701 tttatgggtt gaacataatg acaaaggcag agtagagtta aattatttaa cttttaatag
     2761 tcttcaagat agaagatctt acactgtata tttagacaaa agagatcgag gcttggtaaa
     2821 tgattattcc gaaataatca attatgaaaa taatctatca agtccatttg aggaaaaaga
     2881 aaataaaaat acattagtaa acacaccaaa aaccaatata ccaaaagaca aaaaagaatt
     2941 tatagaaaaa ttaaatactg aaatcttagc attaattatt aatgaagagt tagaaaatag
     3001 agaagaagca attaaacaca ttgaaagtat tcaaggtgta aaaattaata gagttagaaa
     3061 aaatcaaata tcaatcaaat gtgatttttt taacgacgat aaaccaatag ttttaaaagg
     3121 tgatatatat gaagagggaa gaaattacag cgattataga aaagaatacg actcaaaacc
     3181 taaacgagat ccacagcttg ttgaagcaaa actcacagag cttaaaagat cattttcagg
     3241 aagaattgaa aaaagaaaaa ttaggaatag agaaagattt aaaatctcac agagcaaaaa
     3301 taaatcagag aatacaaaag atattgaaag agaaaatatc aatattgaat atagatttat
     3361 taacaataat attgatttta ctgtcaacaa caacggcttt acaaataaca acgatagttt
     3421 atttgctatg gagaaattaa aaaatgagtc aattaattca gaacataaaa caaaaacaac
     3481 aacagaagaa acagcaagat cagaaagaaa aagagatatt gaacagatta atcagcaaca
     3541 acaattcatt aatagaagag ttgaagagat tagacgaacg cagcagcaga tcggaaaatc
     3601 tcttgactca acagaggaaa gaattggaag aaatcgaaga gcattatact caattgtatc
     3661 tacttttaga agatacatta gaacgttttc agcatattct agaaaaaacc aaaacaaaag
     3721 atactttgaa gaaaaaagac gaattgaaga agaaaaacaa tttacccaaa ggagaagaaa
     3781 aaaatttata tattgaggat ataaaatcaa tgcttaattt ccttttggaa caatacgaaa
     3841 aacaaaacac tataaccgcg aacaaataaa gtcctgattt atcagggctt ttttgtgagg
     3901 ggttgacctg tccggtagga cggttttttc ttttatatat tcgtcagata tatttgaat
//
LOCUS       DADXDL010000200         3849 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.200, whole genome shotgun sequence.
ACCESSION   DADXDL010000200 DADXDL010000000
VERSION     DADXDL010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3849)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3849)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3849
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.200"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            689..973
                     /locus_tag="IRB70_004818"
     CDS             689..973
                     /locus_tag="IRB70_004818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088880.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634618.1"
                     /translation="MSRLSHLSEHSAAAVCKGPSSLNARGLPGGEDDVSSYLSPRRKR
                     SFLTVASIGWAPVALFSVAVRACVLPCVIEKVLMVNPAANAESVVRLAAR"
     gene            1253..2668
                     /locus_tag="IRB70_004819"
     CDS             1253..2668
                     /locus_tag="IRB70_004819"
                     /EC_number="2.7.7.13"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019725197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-1-phosphate
                     guanylyltransferase/mannose-6-phosphate isomerase"
                     /protein_id="HBC0634619.1"
                     /translation="MLLPVIMAGGTGSRLWPMSRELYPKQFLRLFGQNSMLQETITRL
                     SGLEVHEPMVICNEEHRFLVAEQLRQLNKLSSNIILEPVGRNTAPAIALAALQATRHG
                     EDPLMLVLAADHIINNQPVFHDAIRVAEQYADEGHLVTFGIVPNAPETGYGYIQRGVA
                     LTDSAHTPYQVARFVEKPDRERAGAYLASGEYYWNSGMFMFRAKKYLSELAKFRPDIL
                     EACQAAVNAADNGSDFISIPHDIFCECPDESVDYAVMEKTADAVVVGLDADWSDVGSW
                     SALWEVSPKDGQGNVLSGDAWVHNSENCYINSDEKLVAAIGVENLVIVSTKDAVLVMN
                     RERSQDVKKAVEFLKQNQRSEYKRHREIYRPWGRCDVVVQTPRFNVNRITVKPGGAFS
                     MQMHHHRAEHWVILAGTGQVTVNGKQFLLSENQSTFIPIGAEHCLENPGCIPLEVLEI
                     QSGSYLGEDDIIRIKDQYGRC"
     gene            2692..>3849
                     /gene="rfbK2"
                     /locus_tag="IRB70_004820"
     CDS             2692..>3849
                     /gene="rfbK2"
                     /locus_tag="IRB70_004820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O9 family phosphomannomutase RfbK2"
                     /protein_id="HBC0634620.1"
                     /translation="MTQLTCFKAYDIRGELGEELNEDIAYRIGRAYGEFLKPGKIVVG
                     GDVRLTSESLKLALARGLMDAGTDVLDIGLSGTEEIYFATFHLGVDGGIEVTASHNPM
                     NYNGMKLVRENAKPISGDTGLRDIQRLAEENQFPPVDPARRGSLRQISVLKEYVDHLM
                     GYVDLANFTRPLKLVVNSGNGAAGHVIDEVEKRFAAAGAPVTFIKVHHQPDGHFPNGI
                     PNPLLPECRQDTADAVRAHQADMGIAFDGDFDRCFLFDDEASFIEGYYIVGLLAEAFL
                     QKQPGAKIIHDPRLTWNTVDIVTRSGGQPVMSKTGHAFIKERMRQEDAIYGGEMSAHH
                     YFRDFAYCDSGMIPWLLVAELLCLKNSSLKSLVADRQAAFPASGEINRKLGN"
BASE COUNT          813 a         1053 c         1149 g          834 t
ORIGIN      
        1 tggcgtccag cacatcacgc gactagatgg gcatcttatt cttctttgct tcaatcctag
       61 agcttcttcc agagaggatt taaagtccat catctcaacc agtgagttgt agccaaagga
      121 tgcagtgtgc aaatagtggt cggcatctcg tggcgatgag attacgtagg tgtaccagtt
      181 tgtcagcccc taagagcaag agtgttcagt ccgttctaca taagtgccga ttttacactg
      241 gcttgcggtt gggatcactt gctttgccgc gtcatgtccg ccagacgtga ggtgaaggac
      301 gttttttctg gcaaaataac cgtggcaaaa ggtgataaat aacaacattt ctcatttgac
      361 tgttagcatc cgaataataa ctttgtgagc ggtcggtggt ttagcgattc gtggcgatac
      421 cctaaaggca gccaataccc tccgggacgg cgtaattttg cttaaagtta tatttttcgt
      481 cagcggaaca tttagcaaat gggcaaaaat cgcgccatgc tttccttcgt tttgtctttt
      541 atatcatagg cttatttttg tttaatgaat gtttaagata tgtattattt gagtaatcta
      601 ttaatcagta ggctttttta tttttattcc cggcgtccag cgctataatc tgcggacgat
      661 tttctttgtg gaatgtgcat tgtagagcat gagtcgctta tcccacctgt cggaacatag
      721 cgccgccgcc gtgtgcaaag ggccatcaag cctgaacgcg cgcggtcttc ctggcggtga
      781 agacgatgtc tcttcttatc tttccccacg tcgtaaacgc tcctttctga cggttgccag
      841 catcggctgg gcgcccgttg cgcttttttc ggtggcggta agggcatgcg ttttgccctg
      901 cgtaattgag aaagtcctga tggttaaccc ggcggcaaat gcggaaagtg tggtgcgttt
      961 ggcggctagg tgagggaaga tacatgttaa aagcagagat atgcctgaag gtatatctct
     1021 gcttttaggt tttcaggaca cgcgttccgc cagactgtca ttgttgccgc tgactgaacg
     1081 atctgccgac agcctgaagc gaaagagggt ggcgcttagc ttggagcacg ggagcagtac
     1141 gcattttggt tgcgacagcc aatggcggta gcgtgcctca aaaaggccac gccacctgac
     1201 ggtcgattga ttgatagtaa aataaagcaa ttatttattt aaggatctca ttatgttact
     1261 tcctgtaatt atggctggcg gtaccggcag tcgtctctgg ccgatgtctc gcgagcttta
     1321 cccgaaacag ttcctccgtc tgttcgggca gaactccatg ctgcaggaaa ctatcacccg
     1381 actctcgggc cttgaagtcc atgaaccgat ggtcatctgt aacgaagagc accgcttcct
     1441 ggtggccgaa cagctgcgcc agctcaacaa gctgtccagc aacattattc ttgagccggt
     1501 cgggcgcaac accgccccgg ccatcgccct ggcggctctc caggccaccc gccacggcga
     1561 ggacccgctg atgctggtcc tcgccgccga ccatatcatc aataaccagc cggtcttcca
     1621 cgacgccatc cgcgttgccg agcagtatgc cgatgaaggc catctggtca ccttcggtat
     1681 cgtgccgaac gccccggaaa ccggctacgg ttacatccag cgcggcgtgg cgctcaccga
     1741 cagcgcccac accccgtacc aggtggcccg cttcgtggag aagccggacc gcgagcgcgc
     1801 cggggcctac ctcgcctccg gggagtacta ctggaacagc ggcatgttta tgttccgcgc
     1861 aaaaaaatac ctctctgagc tggccaaatt ccgcccggat atcctcgaag cctgccaggc
     1921 cgcggtgaat gccgccgaca acggtagcga cttcatcagc attccgcatg acattttctg
     1981 cgagtgcccg gacgagtccg tggactacgc ggtgatggag aaaaccgctg atgcggtggt
     2041 ggtcggtctc gatgctgact ggagcgacgt tggctcctgg tccgcactat gggaggtcag
     2101 cccgaaagac gggcagggta atgtcctcag cggtgacgcg tgggtgcaca acagcgaaaa
     2161 ctgctacatc aacagcgacg agaagctggt agcggccatc ggtgtggaga acctggtgat
     2221 tgtcagcacc aaggacgccg tgctggtgat gaaccgcgag cgttcccagg acgtgaagaa
     2281 ggcggtcgag ttcctcaagc agaaccagcg cagcgaatac aagcgccacc gcgagattta
     2341 ccgtccctgg ggccgctgcg acgtggtggt ccagaccccg cgcttcaacg tcaaccgcat
     2401 cacggtgaaa ccaggcggtg ccttctcgat gcagatgcac caccatcgcg ccgagcactg
     2461 ggttattctc gccggcaccg gtcaggtgac ggtcaacggc aagcagttcc tgttgtccga
     2521 gaaccagtcc acctttattc cgattggcgc cgagcactgc ctggaaaacc ctggctgtat
     2581 tccgctggaa gtgctggaga tccagtcggg gtcgtacctc ggcgaggacg acattattcg
     2641 tattaaagac cagtatggtc gttgctaatt tttttcggga caaaacgcag aatgacacag
     2701 ttaacatgct ttaaggctta tgacatccgt ggtgaactgg gcgaggagct gaacgaggac
     2761 atcgcctacc gtatcggccg cgcctacggc gaatttctga aacccgggaa gatagtggtg
     2821 gggggcgatg tgcgcctcac cagcgagtcg ctgaagctgg cgttggcccg cgggctgatg
     2881 gacgccggca ccgacgtgct ggatatcggc ctgagcggca cggaagagat ttacttcgcc
     2941 accttccacc tcggggtgga cggcggcatc gaggtgacgg cgagccataa cccgatgaac
     3001 tacaacggca tgaagctggt gcgcgagaac gcgaagccca tcagcggcga caccggcctg
     3061 cgggatatcc agcgcctggc ggaggagaac cagttcccgc cagtggaccc ggcgcgtcgc
     3121 gggagcctgc gccaaatttc ggtgctgaag gagtacgttg accacctgat gggctacgtg
     3181 gacctggcga acttcacccg tccgctgaag ctggtggtga actccggcaa cggggcggcg
     3241 gggcacgtga ttgatgaggt ggagaaacgc ttcgcggcgg ccggggcgcc ggtgaccttt
     3301 atcaaggtgc atcaccagcc ggacggccat ttcccgaacg gtatcccgaa cccgctgctg
     3361 ccggagtgcc gccaggacac cgccgacgcg gtgcgtgcgc atcaggcgga catgggtatc
     3421 gcctttgacg gcgacttcga ccgctgcttc ctgttcgatg acgaggcgtc gtttatcgag
     3481 gggtactaca ttgtcggcct gctggcggaa gcgttcctgc agaagcagcc gggggcgaaa
     3541 atcattcacg acccgcgtct gacgtggaac acggtggaca tcgtgacccg cagcggcggc
     3601 cagccggtga tgtcgaagac ggggcatgcg ttcatcaagg agcggatgcg ccaggaagac
     3661 gccatctacg gcggggagat gagcgcgcac cattacttcc gcgacttcgc ctactgcgac
     3721 agcgggatga tcccgtggct gctggtggcg gagctgctgt gcctgaagaa cagctcgctg
     3781 aaatcgctgg tggcggaccg ccaggcggcg ttcccggcgt cgggggagat caaccgcaag
     3841 ctgggaaat
//
LOCUS       DADXDL010000201         3782 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.201, whole genome shotgun sequence.
ACCESSION   DADXDL010000201 DADXDL010000000
VERSION     DADXDL010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3782)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3782)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3782
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.201"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            109..2388
                     /gene="ydeP"
                     /locus_tag="IRB70_004821"
     CDS             109..2388
                     /gene="ydeP"
                     /locus_tag="IRB70_004821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance putative oxidoreductase YdeP"
                     /protein_id="HBC0634621.1"
                     /translation="MKKKIESYQGAAGGWGAVKSVANAVRKQMDIRQDVIAMFDMNKP
                     EGFDCPGCAWPDPKHSASFDICENGAKAIAWEVTDKQVNASFFAENTVQSLLTWGDHE
                     LEAAGRLTQPLKYDAVSDCYKPLSWQQAFDEIGERLQSYSDPNQVEFYTSGRTSNEAA
                     FLYQLFAREYGSNNFPDCSNMCHEPTSVGLAASIGVGKGTVLLEDFEKCDLVICIGHN
                     PGTNHPRMLSSLRALVKRGAKMIAINPLQERGLERFTAPQNPFEMLTNSETQLASAYY
                     NVRIGGDMALLKGMMRLLIERDDAASAAGRPSLLDDEFIQTHTVGFDELRRDVLNSEW
                     KDIERISGLSQTQIAELADAYAAADRTIICYGMGITQHEHGTQNVQQLVNLLLMKGNI
                     GKPGAGICPLRGHSNVQGDRTVGITEKPSAEFLARLGERYGFTPPHAPGHAAIASMQA
                     ICTGQARALICMGGNFALAMPDREASAVPLTQLDLAVHVATKLNRSHLLTARHSYILP
                     VLGRSEIDMQKSGAQAVTVEDSMSMIHASRGVLKPAGVMLKSECAVVAGIAQAALPQS
                     VVAWEYLVEDYDRIRNDIEAVLPEFADYNQRIRHPGGFHLINAAAERRWMTPSGKANF
                     ITSKGLLEDPSSAFNSKLVMATVRSHDQYNTTIYGMDDRYRGVFGQRDVVFMSAKQAK
                     ICRVKNGERVNLIALTPDGKRSSRRMDRLKVVIYPMADRSLVTYFPESNHMLTLDNHD
                     PLSGIPGYKSIPVELEPSN"
     gene            2636..2833
                     /gene="safA"
                     /locus_tag="IRB70_004822"
     CDS             2636..2833
                     /gene="safA"
                     /locus_tag="IRB70_004822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system connector SafA"
                     /protein_id="HBC0634622.1"
                     /translation="MHATTVKNKITQRDNYKEIMSVIVVVLLLTLTLIAIFSAIDQLG
                     ISEMGRIARDLTHFIINSLQD"
     gene            2908..3669
                     /gene="ydeO"
                     /locus_tag="IRB70_004823"
     CDS             2908..3669
                     /gene="ydeO"
                     /locus_tag="IRB70_004823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid stress response transcriptional regulator
                     YdeO"
                     /protein_id="HBC0634623.1"
                     /translation="MSLVCSVIFIHHAFNANILDKDYAFSDGEILMVDNAVRTHFEPY
                     ERHFKEIGFNENTIKKYLQCTNIQTVTVPVPAKFLRASNVPTGLLNEMIAYLNSEERN
                     HHNFSELLLFSCLSIFAACKGFITLLTNGVLSVSGKVRNIVNMKLAHPWKLKDICDCL
                     YISESLLKKKLKQEQTTFSQILLDARMQHAKNLIRVEGSVNKIAEQCGYASTSYFIYA
                     FRKHFGNSPKRVSKEYRCQRHTGMNTDNTMSALAI"
BASE COUNT         1062 a          837 c          867 g         1016 t
ORIGIN      
        1 agtagtcccc tactcttata tatccatatt gacgataatc cctttgtata tactgtgcat
       61 catcgctatt tcaaatccta ataattcatt tccacacagg ataagtagat gaagaaaaaa
      121 attgaatcct accagggggc tgccggtggt tggggtgctg ttaaatccgt agcgaatgca
      181 gtacgtaagc agatggatat acgccaggat gttattgcca tgtttgacat gaataagcca
      241 gagggctttg actgtccggg ttgtgcatgg ccagatccta agcacagtgc gtcattcgac
      301 atttgtgaaa acggcgcaaa agcaatcgcc tgggaagtca cggataagca ggtaaacgcc
      361 tctttctttg ctgagaatac ggttcaatca ttacttacct ggggagacca cgagcttgag
      421 gctgcggggc gtctcaccca gcctttgaaa tatgatgccg tcagcgactg ttacaagcca
      481 ttaagctggc aacaagcttt cgacgaaatt ggcgaacgcc ttcaaagcta tagtgatccc
      541 aatcaggttg aattctatac ttcgggccgc acttccaatg aagctgcctt tctttatcag
      601 ctttttgccc gtgaatacgg gagcaataac ttccccgact gctccaacat gtgccatgaa
      661 ccgaccagtg tgggtttggc agcgagtatc ggtgtaggta aagggaccgt gttgctggaa
      721 gactttgaga aatgcgattt agtcatttgc attgggcata accctggtac aaaccaccct
      781 cgcatgctga gttcgttgcg cgctttagtg aaacggggag cgaaaatgat cgccatcaat
      841 cctctacagg aacgtggcct ggagcgattt accgcaccgc aaaacccgtt tgaaatgctg
      901 acgaactctg agactcagtt ggccagtgcc tactacaacg tgcgcattgg tggtgatatg
      961 gcgttgctca aggggatgat gcgcctgtta attgagcgcg atgatgctgc aagcgccgca
     1021 ggtcggccct cattgctgga tgacgaattt attcaaacgc ataccgtcgg ctttgacgag
     1081 ctacgccgtg acgttctcaa ttccgagtgg aaagatatcg agcgtatttc tggactaagt
     1141 cagactcaaa tcgccgaact ggctgatgca tatgccgctg ccgaccgcac cattatctgt
     1201 tacggaatgg ggatcactca gcacgaacat ggtacccaga atgtacagca actggtcaat
     1261 ctgctgttga tgaaaggtaa cattggcaag cctggtgcgg gcatctgccc actacgaggt
     1321 cactctaatg tacagggcga ccgaaccgtc ggtatcaccg agaaaccgtc tgcagagttt
     1381 ctggctcgcc tgggtgagcg ctatggtttc accccacctc atgcacctgg acatgctgca
     1441 attgccagca tgcaagcaat atgtacgggg caagctcgag cattgatctg catggggggc
     1501 aactttgcgc tggcaatgcc agatcgggaa gcgagcgctg taccgttaac gcaattagat
     1561 ttggctgtac acgtagccac taagcttaac cgctctcatc tgctgaccgc acggcatagc
     1621 tatattctgc cggttctggg acgtagcgag attgacatgc aaaaaagcgg tgcgcaggcg
     1681 gtaaccgttg aagattcaat gtcgatgatt catgcctcgc gtggtgtgtt aaaacccgcc
     1741 ggtgtaatgc tgaaatcaga gtgtgcagtg gtcgcgggaa tcgcgcaggc agcactaccc
     1801 cagagcgtgg tagcctggga gtatctggtg gaagattatg atcgcattcg caatgacatt
     1861 gaagctgtgc tgccagagtt tgccgactat aaccagcgca tccgtcatcc tggtggtttt
     1921 cacctgataa acgcagctgc tgaaaggcgc tggatgacgc cgtcaggtaa ggctaatttc
     1981 attaccagca aagggctgtt agaagatccc tcttcagcgt ttaacagtaa actggtcatg
     2041 gcgacagtac gcagccacga tcagtacaac acgacgattt atggtatgga tgatcgctat
     2101 cgaggtgtat tcggtcaacg agatgtggtc tttatgagtg ctaaacaagc taaaatttgc
     2161 cgtgtaaaaa acggcgaaag agttaatctt attgcactca cgccagacgg taaacgtagc
     2221 tcacgacgca tggatagatt aaaagtggtc atttacccta tggctgaccg ctcactggtg
     2281 acctattttc cagaatcgaa tcacatgcta acacttgata accacgatcc attaagtggc
     2341 attcctggct ataaaagtat tccggttgaa ttagaaccat caaattaatg cctcttctca
     2401 tttcttctgc tgtcatccgc acagcagaag aattcctcat tgactattat cgcgcaattt
     2461 gctcacatgg attaaattag actacatact ataagatata aacttctgcc tacagctgta
     2521 agaaactccg ctcagtactg aagcaccagt cctatttcct cttttttcca gcctgttata
     2581 ttaagcatac tgattaacga tttttaacgt tatccgctaa ataaacatat ttgaaatgca
     2641 tgcgaccaca gtgaaaaaca aaatcacgca aagagacaac tataaagaaa tcatgtctgt
     2701 aattgtggtt gtcttattac tgacacttac gttgatagcc attttttcgg caattgatca
     2761 gctgggtatt tcagaaatgg gtcgcattgc aagagatctt acacatttca ttatcaatag
     2821 tttgcaagac tgaaaataaa cagcaaatta taaatatgaa atgttaaaaa agtatcgata
     2881 aaaactttat tgttttaagg agataaaatg tcgctcgttt gttctgttat atttattcat
     2941 catgccttca acgctaacat tttagataaa gattacgcct tctctgacgg cgagatcctg
     3001 atggtagata acgctgttcg tacgcatttt gaaccttatg agcggcattt caaagaaatc
     3061 ggatttaatg aaaataccat taaaaaatat ctacaatgca ctaacattca gacagtgacg
     3121 gtgcctgttc ctgcgaagtt tttacgtgct tcaaatgtac cgactggatt gcttaatgaa
     3181 atgattgctt atctcaactc ggaagaacgc aatcatcata atttttcaga acttttgctt
     3241 ttttcttgcc tgtctatttt tgccgcatgc aaaggtttca ttacactatt aactaacggt
     3301 gtgctatccg tttccgggaa agtgagaaat attgtcaaca tgaagctggc gcacccatgg
     3361 aagctgaaag atatttgtga ctgcctgtac atcagtgaaa gcctgttgaa gaaaaaacta
     3421 aagcaagagc aaacgacatt ctcacagatt cttttagatg ccagaatgca gcacgcaaaa
     3481 aatttgatac gcgtagaagg ttcagtcaat aaaattgccg aacaatgtgg ttatgcgagt
     3541 acatcttatt ttatttatgc gttccgcaaa catttcggca acagtccaaa gagagtttct
     3601 aaggagtacc gttgtcaaag gcacaccggt atgaacacgg acaacacgat gagtgcttta
     3661 gctatttgat tatttgctaa cgagtagtca accacacacg ctgcgtaaga attaaatggg
     3721 gcagccattc cctgccccgc gttgttttta ggtgatatat ttcttgaaat aaataagtga
     3781 ca
//
LOCUS       DADXDL010000202         3775 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.202, whole genome shotgun sequence.
ACCESSION   DADXDL010000202 DADXDL010000000
VERSION     DADXDL010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3775
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.202"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(254..364)
                     /locus_tag="IRB70_004824"
                     /pseudo
     CDS             complement(254..364)
                     /locus_tag="IRB70_004824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008439260.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber assembly protein"
     gene            complement(384..677)
                     /locus_tag="IRB70_004825"
                     /pseudo
     CDS             complement(384..677)
                     /locus_tag="IRB70_004825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000355605.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(720..1760)
                     /locus_tag="IRB70_004826"
     CDS             complement(720..1760)
                     /locus_tag="IRB70_004826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001544649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tail fiber domain-containing protein"
                     /protein_id="HBC0634624.1"
                     /translation="MVTKTVIPDDIKTLKSDVSKLKTDQGNYATKSYVDNKTTWNGYC
                     NVIYDQKTLPTTGTIFSGKLHLSNKTGETENAYSDIYTRKNIDGTKDTMTRIVTHNGT
                     KGIFWDFSDLYGGTLIFPGSDGYLKMGNCLMSYGVRGSNALIKFDNTDSLQIKYANHG
                     STMTLNTQGTAYSGVSTLLWGNSSRPVVYEIRDDGGLFLFYAQRNPDKTYQLEINGSC
                     KATSFDQVSDRDLKENIQVIDNATERIRLMNGYTYRLKSNGMPYAGVIAQEALNAIPE
                     SVGSTIKYKSGDNGSDGEEGERYYTVDYSGVTGLLVQVARESDDRITALEEENAELRQ
                     RLSAIEAALASK"
     gene            complement(1773..2042)
                     /locus_tag="IRB70_004827"
     CDS             complement(1773..2042)
                     /locus_tag="IRB70_004827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001204893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634625.1"
                     /translation="MRDITLRFDNREQFNAIVYDSGLFSLEEENGVLVDVIGCIIDYE
                     EPENERCTGIDRGGFFVNMRIVDSSKNISSLMPFITTDQHVRTWA"
     gene            complement(2042..>3775)
                     /locus_tag="IRB70_004828"
     CDS             complement(2042..>3775)
                     /locus_tag="IRB70_004828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001598826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBC0634626.1"
                     /translation="ETAAKNSQAAAAESESAAAGSATSAAGSATAAANSQKAAKTSET
                     NAKSSQTAAKTSETNAKASETAAKNSQDAAAQSESAAAGSASAAANSQKAAKTSETNA
                     KTSETKAAASEIEATSAATRAENAARIAEDAADPASVPPLPDIWLPLNDSLEAITGYA
                     PGYKTITIGSDEITMPVNGICQFSRASSATYIDKSGHITVAGNNVPRFEKYGLLIENQ
                     RTNMFVNSFNPDAWNKSGGISVTSSTDEFEFKYGRFTVGSDIAGTTTGRNICTVAGNK
                     GIDVTGDDQYSKGPYVTASFRVRSDLNVRARIRFERYNSEGYTFLCDAYLSLQTHELQ
                     ITGGNAQLLTANFEIDPGSGWIYFQATLKCLPEWGMVGTQLQIAADRAVGAFATGDWI
                     EVTTPQFEYGACATSFIITTTEPATRASDLCKFPLMKNMYTMPFTFMVEVHKNWFISH
                     NAAPRVIDSENHQSGGPFIMGFGSSGTISQDGYSYCDIGGANRRVYESCGVRDLVMGF
                     RVKADGMTCSFANKHISTETKTVWKYIREAAVIRIGGQTTTGLRHLNGHIKNLRFWNR
                     ALSDTQLKEYV"
BASE COUNT          985 a          948 c          693 g         1149 t
ORIGIN      
        1 aaaagagtat catttttact tgcatttctt atcaagtcac attcaacaac agtaaaaaaa
       61 cattattaga accattcaat taacaaaaaa ccaacatcca gcttgcttaa tttttcttta
      121 ttaaacgaca ttgaaaatca attgataaaa tacatctaaa caaccttttg gggcgcaaaa
      181 gcataacatc aaacaaacaa ataacacacc gaaaaaactc acaattaata acctatgata
      241 tacatactgt ttattatggt tgaataagcc actcgatatc tggtgctacg gaagtgtcca
      301 cacggtttag cagcacccga tactttttcc aggcttccag caacgagttt tcttcctccg
      361 ttgcatatac agctcacctt ttttcaccca cgattaacca acagccagac cagcagacac
      421 gccaccaccg gcacagcaaa atccatcagg cttgccacat cccacgcgcg cggatcaaaa
      481 ccgccccacc acggcatatt cattcgcttg ccatgcccga acatttcgat ccagcgatat
      541 tctgcctagg tgtgttcacg cgcaatgaag aacgtacaac cggctatcgc cccgtaagcc
      601 cagttcccgg taaaaagacc aatcagtagc tgcgcagcca cagcacaaag cgcatgaagg
      661 aaaggtgtta tatccatttt catcctaccc aataaaacgg ggcgctcggc cccttaatat
      721 tatttagacg caagcgccgc ctcaattgca gataatcttt gtcttaattc tgcgttttct
      781 tcttccagtg ctgttatcct gtcgtctgac tctctggcta cctgaacaag caaacccgtt
      841 acgcctgagt aatcaacggt atagtatctt tctccctctt ctccatcaga cccattgtcc
      901 ccgctcttgt actttattgt gctaccaact gattcaggga ttgcattaag tgcctcttgc
      961 gcaataacgc cagcataagg cataccatta gacttgagac ggtaagtata cccattcatt
     1021 aatctgatgc gctcagtggc attatcaata acctgaatgt tttctttaag atctctgtcc
     1081 gacacctggt cgaatgatgt agccttgcat gacccgttta tctcaagctg ataggtttta
     1141 tctgggttcc tttgtgcata aaacaaaaaa agcccgccat catccctaat ttcataaaca
     1201 actggacgac tggaatttcc ccataataac gtcgacacac cagaatacgc cgtaccttgc
     1261 gtgtttagtg tcatggtcga cccgtgatta gcatatttga tctgcaatga gtctgtatta
     1321 tcaaacttaa taagcgcgtt acttccccgc acaccatacg acatgagaca gttccccatc
     1381 ttaaggtaac catcactgcc tggaaaaatt aaagttcctc cgtaaagatc actaaagtcc
     1441 caaaagatac cttttgtccc gttatgtgtg acgatcctcg tcattgtatc tttagtacca
     1501 tcaatatttt ttctggtata tatgtcacta taagcgtttt ccgtttcacc agtcttattt
     1561 gacaaatgca gcttaccgct gaatatagtt ccagttgttg gcaatgtttt ttgatcatag
     1621 attacattgc aataaccatt ccatgttgtt ttattgtcta cataagattt tgttgcgtag
     1681 tttccttgat cggtttttaa tttactaaca tccgatttta gcgttttgat gtcatcagga
     1741 attactgttt ttgtaaccat tgtcttactc cattaagccc atgtccttac atgctgatct
     1801 gtcgtaatga aaggcattaa agaagatatg tttttactgc tatcaacaat cctcatgttt
     1861 acgaaaaaac caccgcgatc aatgcccgta catctttcgt tttctggctc ctcgtaatca
     1921 ataatgcagc caataacatc aacaagaacc ccattttctt cttcaagact gaacaggcca
     1981 ctgtcatata caattgcgtt aaactgttct ctgttatcga atcgtaatgt tatatcccgc
     2041 attatacgta ttccttaagc tgcgtatctg acaatgctct gttccagaaa cggaggtttt
     2101 ttatatgacc attaaggtgt cgtaatcctg tcgtcgtttg ccccccgatt cgaatcacgg
     2161 ctgcttcacg aatatatttc catactgttt tggtttcagt gcttatatgc ttatttgcaa
     2221 atgagcatgt catgccgtca gccttaaccc tgaatcccat aacgagatct cttactccgc
     2281 atgactcata tacacgccgg ttagccccgc ctatatcgca atacgaataa ccatcctgac
     2341 tgatagttcc agaagaacca aaccccataa taaatgggcc tccggactgg tgattttctg
     2401 aatcaatgac acgcggtgca gcattatgag aaataaacca gtttttatgg acttccacca
     2461 tgaacgtaaa aggcatggta tacatatttt tcatcagcgg aaatttacat aaatctgatg
     2521 cacgagtcgc tggctctgtt gtcgttatga taaaggaagt tgcacaagca ccatactcga
     2581 attgcggggt ggttacttct atccagtcac ctgttgcaaa agcccccact gctctgtcgg
     2641 ctgcaatttg cagctgcgta ccaaccattc cccattctgg cagacatttc agtgttgcct
     2701 gaaaatatat ccatccacta ccagggtcga tttcaaagtt tgctgttaat agctgggcat
     2761 taccacccgt aatttgtagt tcatgagtct gtaatgacaa ataggcgtca caaaggaaag
     2821 tgtatccttc cgagttatac cgttcaaaac ggatacgtgc gcgaacattg agatcacttc
     2881 ttaccctgaa cgacgcggta acatacggac ctttactgta ctgatcatcg ccagtcacat
     2941 ctatgccttt attaccagca actgtgcata tatttctccc tgttgtcgtt cctgctatgt
     3001 cgcttcctac tgtgaaacgt ccatatttaa actcaaattc atctgttgat gatgttacag
     3061 atataccacc gcttttattc cacgcatcag gattaaaact atttacgaac atgtttgttc
     3121 gctgattctc tatcagcaaa ccatattttt caaaacgagg aacgttattc cctgccacgg
     3181 taatatgccc ggacttatca atatacgttg ctgatgaagc gcggctaaat tggcatatgc
     3241 cattaacagg cattgttatt tcatcactgc cgatggttat tgttttatag cccggggcat
     3301 accctgttat cgcttccaga gaatcattca agggtagcca gatatcagga agcggaggga
     3361 ctgaagcagg atcagcggca tcttctgcaa tccgggctgc attctctgct cttgttgcgg
     3421 ctgacgttgc ttctatctcg ctggctgctg cttttgtttc actcgtcttt gcgttagttt
     3481 cactggtttt tgcagctttt tggctattag ctgccgcact tgcagaacca gctgcggcac
     3541 tctcgctttg ggccgctgca tcctgactgt tttttgccgc agtttcgctg gctttggcat
     3601 tcgtttcgct ggtcttcgct gccgtctggc tggactttgc gttagtttca ctcgtcttcg
     3661 cagctttctg gctgttagcc gcagcagttg ctgatccagc tgctgaagtc gcagaaccgg
     3721 ctgctgcgct ctcgctttca gctgctgcag cctggctatt tttcgccgca gtttc
//
LOCUS       DADXDL010000203         3692 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.203, whole genome shotgun sequence.
ACCESSION   DADXDL010000203 DADXDL010000000
VERSION     DADXDL010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3692)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3692)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3692
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.203"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1043)
                     /locus_tag="IRB70_004829"
     CDS             complement(<1..1043)
                     /locus_tag="IRB70_004829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000382418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBC0634627.1"
                     /translation="MDVFNTPVSRKGTYCTQWDFCEDRFGVKDVLPFSISDMDLPIPE
                     AIIRALRKRLEHPILGYSRWQHGEYLNAIVNWYYQQYQTDIKPEWITYSPSVMYSIAK
                     AIELLTSHGDNILVFTPVYNAFFDVIKHSERNILTASLIIKNEGGYAINWQDFDLKIK
                     SAKMVLLCNPHNPTGTVWSEEELHKIAASCTRHNVWLCSDEIHSDFVFNRSFTSALKI
                     KKEKVVVFNSISKTFNVPALTGSYMISTDDNFNHKFRTISRYRDFVNSPSVLNIIATI
                     IAYNECEGWLKSLKAHIASNIQFTQQYLNENIPELIVRPADGCYFSWIDCSAIGYPFD
                     EFYSRLIHEGKVG"
     gene            complement(1043..2623)
                     /locus_tag="IRB70_004830"
     CDS             complement(1043..2623)
                     /locus_tag="IRB70_004830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000810568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBC0634628.1"
                     /translation="MKQKKAWSFFQSLGKAFMYPIALLSVCGMMLGLGSGLASDDMAK
                     LIPFLAIPIIKTILDFIVSLGLFAFVNLPVLFAIAIPLGLLKEKEDKAYGAFSGLIGF
                     MAMHLGTNFYLKQHDLLVAADQMSTHGQTIILGIQSYNTSVLGGIVAGLLVASMYKKI
                     VNLRIPESLGFYSGPRLVPIITLIVMSGFGLIIPFIWPPFFNLFMLIGHWISTSGPVG
                     YFFYAVAERVTIPFGLNHLVTSVFRFTPIGGSAVIGGEEYYGTLNMFMAYVKENAVIP
                     LDLAGKMEQGKLMIQYGLAGAALAMYRTAHAQNRKAIKALLISGVLTVIIGGVSEPIE
                     FLFLFVSPLLFVFHAFMNGFANMVLPYMGVKMGFTGDLIQFISFGVLRGTRTGWPIAV
                     CVEVAYFFIYYFVFRWTILKFNLMTVGREESSPVTLNAHEDTAIADIPTLDKSELQAA
                     EQMVKALGGKENIKSLDNCVTRLRLTIADMGLIDEAAIKRAGGIAVVKLDQNTLQVII
                     GTKVIALRRDMDNYMGIC"
     gene            complement(2655..3479)
                     /locus_tag="IRB70_004831"
     CDS             complement(2655..3479)
                     /locus_tag="IRB70_004831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001606056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBC0634629.1"
                     /translation="MIIEKVMNNNCVQASMNGQEVIISGPGVGYNKKYGMSVPEHPAN
                     RIFYVRNEQKNKLYKLIEHVDIEYVFVAEKIVYYAECNLERKLNPSLLLILADHISNA
                     ISRVSSGIQINNFFLEEIKALYKAEYAISRDALTIINEQFSFQLPDDEIGFIALHILN
                     NYENSSDYESVRIIELSQKITEIIEGIYNRKVDRSSFNYSRFMMHLKYFSNRVLCNEK
                     IKQKDIGDIYEQFLEKDILLQRAIHEIERYLYATFKYELILEEKLYLSIRTKVLMD"
BASE COUNT         1167 a          791 c          648 g         1086 t
ORIGIN      
        1 atgcccactt tgccttcatg aattaatcga ctgtaaaatt catcaaaagg ataaccaata
       61 gcagaacaat ctatccagga aaaatagcaa ccatcagctg gccttacgat caattctgga
      121 atattttcat tcagatactg ctgggtgaat tgaatgttag aggcaatatg tgcctttaat
      181 gactttaacc atccctcaca ttcgttatag gcaataatag ttgcaattat attcagtact
      241 gatggggagt ttacaaaatc gcgatacctc gatatcgttc tgaacttatg attaaaatta
      301 tcgtcagttg aaatcatata cgatcctgtt agtgcaggaa cattaaatgt tttcgatatc
      361 gagttaaata ctactacttt ttcttttttt attttaagcg cggatgtaaa gctacgatta
      421 aaaacaaaat cactatggat ttcatctgaa cataaccaga cattatgcct tgtacagctt
      481 gcagcgattt tatgcagttc ttcttccgac cagactgttc ctgtcgggtt atgaggatta
      541 cataataaca ccatctttgc gcttttaatc ttaagatcaa aatcttgcca gttgatagcg
      601 tagcccccct cattttttat aatcaaagag gctgtcagaa tatttcgctc gctatgttta
      661 attacatcaa aaaatgcatt atagacaggt gtaaaaacga gaatattatc accatgcgat
      721 gtcaataact ctattgcttt tgcaatagag tacatcacac tggggctata ggttatccat
      781 tcaggtttaa tatctgtttg atattgttga taataccagt ttactatcgc attcagatat
      841 tcaccatgtt gccaacgact gtaccctaaa atcgggtgtt ccagacgttt tcttaatgcc
      901 ctgatgatag cttccggtat cggaagatcc atatctgaaa tagagaatgg taatacatct
      961 tttacaccaa atctgtcctc gcaaaagtcc cattgggtac aatatgttcc tttgcgggaa
     1021 acaggggtat taaaaacatc catcagcata tccccatgta gttatccata tcccgacgca
     1081 aggcgatgac tttagtaccg ataatgactt gtagggtatt ttgatcaagt ttaacaaccg
     1141 caattccgcc agctcttttt attgctgcct cgtcaatcaa tcccatatct gcgattgtta
     1201 aacgtaaacg agttacgcaa ttatccaggg atttaatatt ctctttacca ccaagtgcct
     1261 taaccatctg ctccgctgct tgcagctctg atttatcaag cgttgggata tccgctatag
     1321 ccgtatcctc atgagcgttc agcgtgacag gactggactc ttcacggcct acggtcatca
     1381 ggttaaattt aagaatagtc caacggaaca caaagtaata aataaagaaa taggccactt
     1441 cgacacacac cgctattggc caacctgttc ttgtgccacg caatacgcca aagctaataa
     1501 attgaatcag atcgccagta aatcccatct tcacgcccat atatggcaag accatgttgg
     1561 cgaatccatt cataaatgca tggaagacaa acagcagtgg actgacaaat aagaacagaa
     1621 actcaatcgg ttcgctgacg ccgccaataa tgactgtaag caccccggaa ataagcaatg
     1681 ctttgatagc ttttctgttt tgagcatgag cagtgcgata catcgccagc gcggcaccag
     1741 ccagaccata ctgaatcatc agtttgccct gttccatttt ccccgccaaa tccagcggaa
     1801 tgaccgcatt ctctttgacg tacgccataa acatgttcag ggtgccataa tactcttcgc
     1861 cgccaatcac agccgaaccg ccgattggcg taaagcggaa aactgacgtc accagatggt
     1921 ttaagccaaa aggaatcgtc acgcgttcgg caactgcata gaagaaataa ccaacaggac
     1981 cggaagttga tatccagtgg ccaatgagca tgaagagatt gaaaaacggc ggccagataa
     2041 aaggaatgat cagaccaaat ccactcatca caatcagtgt aatgataggc accagacgtg
     2101 ggccgctata aaaacctaat gattctggaa tgcgtaaatt aacgatcttt ttatacatgc
     2161 tggcgactaa taacccagca acaattcctc ctaacacgct ggtattgtag gactggatcc
     2221 ccagaatgat ggtttgccca tgtgtcgaca tttggtcagc agcgaccaat aagtcgtgct
     2281 gtttaagata aaagttcgtt cccagatgca tcgccataaa accaattaag ccagaaaaag
     2341 cgccataggc tttatcctct ttctctttta ataatcctaa gggaattgct atcgcaaaca
     2401 atacaggtaa attaacaaag gcaaacaaac caaggctaac aatgaaatca agtatggttt
     2461 taattattgg aatagccaga aatggaatta actttgccat atcatcactg gctaaaccac
     2521 ttcccagccc tagcatcatg ccacatacac ttagcagagc aatgggatac ataaatgcct
     2581 tccccaggct ctgaaaaaaa ctccaggctt tcttttgttt catgtgggtt atctcatata
     2641 aatgttatat ataattagtc cattaatact ttggtacgaa tagagagata tagtttttct
     2701 tctaaaatta attcatattt aaaagtggca tacagatacc gttcaatttc atgaattgcg
     2761 cgctgtaaca ggatgtcttt ctcaagaaac tgctcataga tgtcaccaat atctttctgt
     2821 tttatctttt cattacataa aactcgatta gaaaaatact taaggtgcat cataaatctt
     2881 gaatagttaa atgaacttct gtccaccttt cggttataaa taccctcgat aatctccgtg
     2941 attttttgag ataattcaat aatccgtacc gattcataat cagatgaatt ttcatagtta
     3001 tttaaaatat gcaatgcaat aaaaccaatc tcatcatccg gaagttgaaa gctaaattgc
     3061 tcattgatga tggttaatgc atcccggctt attgcatatt ctgctttgta caacgctttg
     3121 atttcctcaa gaaaaaaatt attgatttgt attccggagg agactctgga tattgcattt
     3181 gaaatgtgat cggcaagaat aagcaatagc gatggattta actttctttc aagattacac
     3241 tccgcgtagt acactatctt ttcggcaaca aacacatact caatatctac atgttcaatc
     3301 aatttataaa gtttgttttt ttgttcattt ctgacataaa aaatccggtt agccggatgc
     3361 tcagggaccg acattccata ttttttgttg taaccgacgc caggcccaga aatgataacc
     3421 tcctgtccat tcatcgatgc ctgtacacaa ttattgttca tgactttttc gatgatcatt
     3481 ccatagctcc caaaaaaaaa ggcaaggcac gtcagaagta ataattactt caaacattgc
     3541 cttgcctgat ttaacagtta caagatgatt aactaatgca tatacattac acggaattgt
     3601 gcttaattaa agagatggtc ggcttatttt tcaagccgac attcaaatat ccgacatcag
     3661 tcacaaaacc agggtctaat attcaggtaa at
//
LOCUS       DADXDL010000204         3472 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.204, whole genome shotgun sequence.
ACCESSION   DADXDL010000204 DADXDL010000000
VERSION     DADXDL010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3472)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3472)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3472
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.204"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(1..285)
                     /locus_tag="IRB70_004832"
                     /pseudo
     CDS             complement(1..285)
                     /locus_tag="IRB70_004832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611787.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3 family transposase"
     gene            429..3446
                     /locus_tag="IRB70_004833"
     CDS             429..3446
                     /locus_tag="IRB70_004833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032490160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Tn3-like element IS3000 family transposase"
                     /protein_id="HBC0634630.1"
                     /translation="MAFEERVQILSEAEQDELYGPPAFTSADQRFFFSLNDKELAIAK
                     SLRHRGQRYMLVVLLGYFKAKPVVLNPGFHQIKQDLKYVYQTVLPGPGCRPFNLTPKE
                     NERIYQRVFQLCNYQRWNVKDHGAALRDYLSQQARAWTAPRHLFDAANEYCSGQKIAI
                     PAYSTLQKIISQVVGDEQEHMAAHLERAMSRGLKQALAELVNGTGPLPFRQLRQSARN
                     FTGTELEKELIVYRHIQHWMPEVDLLLSTLSLSQKNLQHLAEKVDYYGAKLKRQTVGS
                     QWLYLLCYLQTRWQQALERIADGFVHHVRQTKQKAKDYAQEAVFKDWQKAAKNVSKAA
                     EVLHLFIDDSIDLQLPFATVRQQALSLLTKRDLESVCLFLNEQRRSVDEAMWQYCDEK
                     ESLRKGLLRELFLCLRFEGCDGTQHLAAALAKTQNELNGQDAQLQTADTRLLSKKSRE
                     FLLDGEGNILIDRYEWFLYQQIPDRLNGQLTLPDITKYRALDADLIDGEHWRKNKYTL
                     LQQSHFTKLAEEPEKLIKQMAMELDTRLYEVGEYLEQEDNRNIILRNPQGKRFWRLPS
                     ASKHHLVNNPFFQQIPTTGIADVLRMVDRDTGFIDCFAHVLGSQSRSRSHEYDLLAIL
                     VGNATNQGIYGMAQISDRTYDQLSTIQANYLRLETLNAANDNINNATAKLPIFRYYNI
                     QEDVIHASADGQKFEARRETFKTRYSSKYFGTQKGVSAMTLIANHAAINARVIGANEH
                     ESHYIFDLLMSNTSDIIPDVLSTDTHGVNHVNFALLDLFGYQFAPRYAQVGKVINDMF
                     DVKEDKEHRIQLCLKKPINTHRIAQHWDTIQRIAVSLKQRKTTQATLVRKLSEYKRNH
                     PLLEALTEYNRLVKANYLLCYIDDASLRNYVQRALNRGEAYHQLRRAVSSVNGDQFRG
                     SSDEEIQLWNECARLVTNAIVYFNSRILSQLLTSFEYQGDTKRIDIVKQASPVAWHNI
                     NLKGTYHFELSEKLPDLEELMRSIEGYLPVSEK"
BASE COUNT          933 a          901 c          857 g          781 t
ORIGIN      
        1 gtcggtatat cgttttctta tctcaccttt ttgaccgtga cagatggctc tggcaacggc
       61 atggcgactt tctccccgat taagctgggt cagaatgcgc cggcggtaat cttcatcatc
      121 aatataatta agcagataca gcgttttgtt gatgcgcccc acttcaatga ttgcctgagt
      181 cagtccggaa ggacgttcac ttttcagcaa tgaacggacc agcactgaaa cctgtacttt
      241 gcccagcttc agggagccag cggtccggat catttcgtcc cactgagggg ttctagggat
      301 tttccgtcca aaaacgacaa agtgctctgg aggccccgcc gtctgtggcc tccagagggg
      361 tattactttt ttcgagatcc ctatttgggc tctgtttgag taagatttag tctttttggg
      421 ctaaatccat ggcattcgaa gaacgtgtcc aaatcttgtc cgaggcagaa caagatgagt
      481 tatatggacc ccccgctttc acctccgccg accaacgctt ctttttctcg ctgaacgata
      541 aggaactggc gatcgctaaa agcctccgtc atcggggcca gcgttacatg ctggtggtac
      601 tgctgggcta tttcaaagcc aagccggtgg tgctgaatcc cggctttcat cagatcaagc
      661 aggacctcaa atacgtttat caaaccgttc taccaggccc aggctgtaga ccctttaatc
      721 tcacgccaaa agagaacgaa cggatttacc aacgtgtttt ccagctctgc aactaccagc
      781 gctggaatgt caaagaccat ggagcggcgt tgagagatta cttatcccag caagccagag
      841 cctggacagc gcctaggcac ctcttcgatg cggccaatga atattgttcg gggcagaaga
      901 tcgcaatccc tgcctacagc acgctgcaaa agatcatcag tcaggtggtg ggagacgaac
      961 aggaacacat ggccgcgcac cttgagcgtg caatgtcacg cggtcttaag caagcactgg
     1021 cggagctcgt gaacggcaca ggtccactgc cgttccgaca gttgcgacaa tcggctcgta
     1081 acttcaccgg aaccgagttg gagaaagaac tgattgtcta tcgccatatc cagcattgga
     1141 tgccggaagt ggatctgctg ttgagcacgc tatcactgtc gcagaaaaat ctgcaacacc
     1201 tggcagagaa agtcgactac tacggtgcca aactgaaacg tcaaaccgta ggcagccaat
     1261 ggctgtattt attgtgctat cttcaaacgc gatggcagca agcgctggaa cgtattgccg
     1321 atggctttgt gcatcatgtc agacagacca aacagaaggc aaaggattat gcgcaggaag
     1381 cggtgtttaa ggattggcaa aaagcagcta aaaatgtcag caaggcagct gaagtactgc
     1441 acctgttcat tgatgacagc attgatctgc aactaccgtt tgcaacagta agacagcaag
     1501 cactgagcct gctgaccaaa agggatctgg aatctgtatg tctcttcctg aacgagcagc
     1561 gacgatcggt cgatgaagcc atgtggcagt actgcgacga gaaagaaagt ctgcggaaag
     1621 gtttgctgcg agagttgttc ctatgtctgc gcttcgaagg ctgcgacggc acccagcact
     1681 tagcggccgc cttggcgaaa acacaaaacg aactcaacgg ccaggacgct cagttgcaaa
     1741 ctgccgacac cagactcctt tccaaaaaat cacgtgaatt cctgctggat ggtgaaggga
     1801 atatcctgat cgatcgttat gagtggttcc tctatcaaca gattcctgat cgcctgaatg
     1861 gccagctgac gctgcctgat atcactaaat accgggcact cgacgccgac ctgatcgacg
     1921 gggaacattg gcgaaaaaac aaatatacgc tgcttcaaca gagccatttt acaaaattag
     1981 cggaggagcc tgaaaagctg atcaaacaga tggccatgga attggatacc cgtttgtacg
     2041 aagtcggcga atatcttgaa caggaagaca accggaatat catcttgcgt aatccgcagg
     2101 gtaaacgctt ctggcgcctg ccttcggcca gcaaacatca tctggtcaac aatcccttct
     2161 tccagcaaat tcccacaacg gggattgcgg atgtactgcg catggttgat cgtgacaccg
     2221 gtttcattga ctgcttcgct catgtgctgg gttcccaatc cagaagccgt tcccatgaat
     2281 atgacctgtt ggcaattctg gtcggcaatg caaccaatca aggcatttac ggcatggcac
     2341 agatctctga tcgtacctat gatcagctca gcactatcca ggcgaactat cttcgcctgg
     2401 aaacattgaa tgctgctaac gacaacatca ataacgcgac agccaagcta cccatcttcc
     2461 ggtactacaa catccaggaa gatgtgatcc acgccagtgc cgatggtcaa aagttcgaag
     2521 cccggcgcga gaccttcaaa acccgttatt cgtcgaagta ctttggcact caaaaaggtg
     2581 tttctgccat gaccttgatc gccaatcacg ctgcgatcaa cgccagagtg atcggcgcca
     2641 acgaacatga atcgcactac atctttgatt tgttgatgag caatacgtca gacatcattc
     2701 cggatgtgct ctcaaccgat acccatgggg tgaaccatgt gaacttcgcg ttactggatc
     2761 tgttcggata ccagtttgcc ccacgctatg cccaggttgg caaagtgatc aatgacatgt
     2821 ttgatgtcaa ggaagacaaa gaacaccgaa ttcagctgtg cttaaaaaag ccaatcaata
     2881 cccatcgtat tgcgcagcac tgggatacca tccaacggat tgcagtatca cttaagcagc
     2941 ggaaaacaac gcaagccacc ttggtgagaa agctctcgga gtacaagcgc aatcacccgc
     3001 tgctggaagc cctgacggaa tacaatcgcc tggtgaaagc gaattatcta ctgtgctaca
     3061 tcgatgatgc cagtttaaga aactatgttc agcgcgcgct gaaccgggga gaggcctatc
     3121 accaactgcg tcgggccgtg agcagcgtca atggggatca gttccggggc agttcagacg
     3181 aagaaatcca gctatggaat gagtgcgctc gcctggtcac caatgccatc gtttacttca
     3241 actccaggat actcagccag ctgttgacca gcttcgaata ccaaggagat accaagagaa
     3301 tagatatcgt caaacaggca tcccctgtgg cctggcacaa cattaacctc aaggggactt
     3361 accacttcga attgagcgaa aaattgccag atctggagga gcttatgcgc tcaatcgagg
     3421 gatatttacc cgtcagcgaa aagtaatacc cctctggagg ccacggacgg cg
//
LOCUS       DADXDL010000205         3440 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.205, whole genome shotgun sequence.
ACCESSION   DADXDL010000205 DADXDL010000000
VERSION     DADXDL010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3440)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3440)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3440
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.205"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..541
                     /locus_tag="IRB70_004834"
     CDS             <1..541
                     /locus_tag="IRB70_004834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBC0634631.1"
                     /translation="IVLGFMSNISIEKGIKDAVNTTLMLREKGIDAKLKIGGVCDNIE
                     IENYLNDTIKSNPSDFEFVGFVDKNSKLDFFKELDWFLFPTRYVNEAQPNVLFESVAA
                     GVPFITIERGCIIGDFPDYPYVMREKENFPEFATKAIIDNITPSSYEKNRAELILKVR
                     HQLNDAELKENTMFENILN"
     gene            558..1676
                     /gene="gmd"
                     /locus_tag="IRB70_004835"
     CDS             558..1676
                     /gene="gmd"
                     /locus_tag="IRB70_004835"
                     /EC_number="4.2.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose 4,6-dehydratase"
                     /protein_id="HBC0634632.1"
                     /translation="MMKKALITGVTGQDGSYLAELLLSKGYEVHGIKRRASSFNTERI
                     DHIYQDPHESNPKFHLHYGDLTDTSNLTRILSEVRPDEVYNLGAMSHVAVSFESPEYT
                     ADCDAIGTLRLLEAIRFLGLEKTTKFYQASTSELYGLVQEIPQKETTPFYPRSPYAVA
                     KLYAYWITVNYRESYGMYACNGILFNHESPRRGETFVTRKITRGLSYISQGLEKCLYM
                     GNLDSLRDWGHAKDYVKMQWLMLQQETAEDFVIATGIQYSVRDFISMAALELGITLKF
                     EGEGVDEKGIVASVNNEISPAVNVGDVIVAVDPRYFRPAEVETLLGDPTKAKDKLGWV
                     PETTLQEMVTEMVASDLEAAKKHSLLKKHGFNVNISME"
     gene            1680..2645
                     /locus_tag="IRB70_004836"
     CDS             1680..2645
                     /locus_tag="IRB70_004836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-L-fucose synthase"
                     /protein_id="HBC0634633.1"
                     /translation="MSRKRIYIAGHNGMVGSALVRNLETRNDVELILKTRQELNLLDQ
                     QAVNNFFKTEDIDEVYLSAAKVGGIMANNTYPADFIYENLMIASNIIHAAHVNDVNKL
                     LFLGSSCIYPKLANQPISEAELLQGTLEPTNEPYAIAKIAGIKLCESYNRQYNRDYRS
                     VMPTNLYGPFDNFHPTNSHVVPALIRRFHEAKENDQAEVIVWGSGNPKREFLYVDEMA
                     AASVYVMELNKNVYDQFTEPMLSHINVGTGRDCSIKELASTIASVVGYKGKITFDSTK
                     PDGTPRKLLDVSRLAALGWTSKLSLHDGLVDTYQWYLDNQDTFRR"
     gene            2649..3095
                     /locus_tag="IRB70_004837"
     CDS             2649..3095
                     /locus_tag="IRB70_004837"
                     /EC_number="3.2.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GDP-mannose mannosyl hydrolase"
                     /protein_id="HBC0634634.1"
                     /translation="MLTDEEFINVIKLTPLISIDFIVKNKRNEILLGKRVNSPARGYY
                     FVPGGRILKDETIDDAFLRLSQTELGISIPKDLWNFHGVYEHFYEDNKYNNLFSTHYI
                     VLAYETKLTDKINFPTNQHSEYKWVLESLVGKDERIHNYTKNYFPA"
     gene            3102..>3440
                     /locus_tag="IRB70_004838"
     CDS             3102..>3440
                     /locus_tag="IRB70_004838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaI"
                     /protein_id="HBC0634635.1"
                     /translation="MKILIYGINFSPELTATGKYSGEMAEWMAREKQDVRAVTAPPYY
                     PEWKVKSPYSSWKYKKEVISNVTVFRCPLYVPKQVSTLKRLIHLTSFTLSSFPQLFRN
                     FFWKPDLVICV"
BASE COUNT         1133 a          558 c          669 g         1080 t
ORIGIN      
        1 aatagtatta gggttcatga gtaatatttc tatagagaaa ggaataaaag atgcagtaaa
       61 tactacctta atgctaagag aaaaagggat tgatgcaaag ttaaagatag gtggtgtctg
      121 tgataatatt gaaatcgaaa attatttgaa tgacacaata aaatcaaatc ctagtgattt
      181 tgaatttgtt gggtttgttg acaagaatag taaactcgat ttttttaaag aacttgattg
      241 gtttttattc ccaacaagat atgttaatga agctcaaccg aatgttttat ttgaatcagt
      301 tgccgctgga gtaccattta ttacaattga aagaggatgc attattggtg atttcccgga
      361 ttatccttat gtaatgaggg aaaaggaaaa ttttccagag tttgctacaa aagctattat
      421 tgataatatc actccttctt cttatgaaaa aaatagggca gaactaattt tgaaagttag
      481 gcatcaattg aatgatgcag aactaaaaga aaacacaatg tttgaaaaca ttttaaatta
      541 accaataatt ggaatagatg atgaaaaagg cgttaattac tggtgtaact ggtcaagatg
      601 gatcttattt ggctgaattg cttttgagta aagggtatga agttcatggt atcaaacgca
      661 gggcgtcctc attcaacacc gaacgtatcg atcatatcta ccaggatcct catgaaagta
      721 atccaaaatt ccatcttcac tatggtgatt taactgacac atcaaactta acccgtattt
      781 tatctgaagt acgtcctgat gaagtttata atttaggggc aatgagtcat gtggctgttt
      841 cgtttgaatc acctgaatat accgccgatt gtgatgcaat aggaactctt cgtcttttag
      901 aggctattcg ctttttagga ttagaaaaga caactaaatt ctatcaagcc tctacttcag
      961 aactttatgg gttagtacaa gaaatacctc agaaagaaac aacaccattt tatccacgat
     1021 ctccatatgc tgtggcaaaa ctctatgcat attggattac tgtaaattac cgtgaatctt
     1081 atggcatgta tgcttgtaat gggattttat tcaaccatga atcaccacgt cgtggtgaaa
     1141 cttttgtgac cagaaaaatt acgcgtggtt tatcctatat ttctcaaggt ttggaaaaat
     1201 gcctatatat gggtaactta gattcattac gtgattgggg acacgctaaa gattacgtga
     1261 aaatgcaatg gcttatgctt caacaagaaa cggcagaaga ttttgtcatt gcaactggta
     1321 tccagtattc agttcgcgat tttatatcaa tggccgctct agaattgggt attactctta
     1381 agtttgaagg agagggtgtt gacgagaagg gaattgttgc ttctgtaaat aatgaaatct
     1441 ctccggctgt caatgtaggt gatgtcattg ttgctgttga tcctcgatat tttcgtccag
     1501 ctgaagtcga aacattactg ggcgatccaa ctaaagctaa agacaaactt ggttgggtac
     1561 cagaaacaac attacaagaa atggtaaccg aaatggttgc ttctgacctt gaggcagcca
     1621 aaaaacattc actccttaag aagcatggct tcaatgtaaa tatctcaatg gagtaaatta
     1681 tgtcccgaaa gcgtatatat atagcaggcc ataatggcat ggtaggttcg gctcttgttc
     1741 gtaatcttga aacgagaaat gatgttgaac ttattttaaa aactagacag gaacttaatt
     1801 tactcgatca gcaagcagta aacaatttct tcaaaactga agacatcgat gaggtttatc
     1861 tctctgctgc taaagttggt ggtattatgg caaataatac ttatcctgct gattttatat
     1921 atgaaaattt aatgatagct tctaatatta ttcatgctgc tcatgtcaat gatgttaata
     1981 aactattgtt tttaggttct tcctgtatat atcctaaact tgctaatcag ccgataagtg
     2041 aagctgaact tttacaagga acgcttgaac cgacgaatga accttatgca atagcaaaaa
     2101 ttgcaggtat aaaattatgc gaatcatata acagacaata taatcgcgat taccggtcag
     2161 ttatgcctac taatctatat gggccttttg ataacttcca tccaactaat tctcatgtgg
     2221 tacctgcgct aatcagacgt ttccatgaag caaaggaaaa tgatcaggct gaggttatag
     2281 tctggggaag cggaaatcct aagcgtgaat ttttatatgt cgacgaaatg gctgctgcca
     2341 gcgtatatgt catggagttg aataaaaatg tatacgatca gtttacggaa ccaatgctct
     2401 ctcatatcaa tgttggcacc ggccgcgatt gctcgataaa agaattagca tctacaattg
     2461 ctagtgtggt cggttataaa ggcaagatta ctttcgatag tactaaaccg gatggcacac
     2521 ctaggaaatt gctagatgtg agccgtttgg ccgcactggg atggacttca aaattatctt
     2581 tacacgatgg gttggttgat acctatcaat ggtatttaga taatcaagat acctttagaa
     2641 ggtgataaat gttaacggat gaagaattta ttaatgtcat caaacttacg cctcttattt
     2701 ctatagattt tattgtaaag aacaagcgta atgaaattct tctaggtaaa cgagtaaata
     2761 gccccgcaag gggctattat ttcgtgcccg gaggacgtat tttgaaagat gaaactatag
     2821 atgatgcatt tcttcgatta agtcaaacgg agttaggtat aagcatacca aaagatttat
     2881 ggaattttca tggcgtttat gaacattttt atgaagataa taaatataac aatttattta
     2941 gcacccatta cattgtactt gcgtatgaaa caaaattaac agacaaaata aactttccta
     3001 ccaaccagca ctctgaatat aaatgggtcc tcgaatcatt agttggtaaa gacgaaagaa
     3061 ttcataatta cacaaaaaat tattttccgg catgaggtta tatgaaaatt ttaatttatg
     3121 ggataaattt tagtccagag ttgaccgcta ctgggaagta ttcaggcgaa atggctgaat
     3181 ggatggctag agaaaaacaa gatgttagag cagttactgc accgccttat taccctgaat
     3241 ggaaagtgaa gtcaccttat tcttcttgga aatataagaa agaggtcata tcaaacgtaa
     3301 ctgtctttcg ttgtcctctt tatgttccta agcaagtttc tacgttaaag cgattaatcc
     3361 atttaacatc atttacactt tcatctttcc ctcaactttt tagaaacttt ttttggaaac
     3421 cagatcttgt aatttgtgta
//
LOCUS       DADXDL010000206         3396 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.206, whole genome shotgun sequence.
ACCESSION   DADXDL010000206 DADXDL010000000
VERSION     DADXDL010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3396)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3396)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3396
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.206"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(26..319)
                     /gene="ybgE"
                     /locus_tag="IRB70_004839"
     CDS             complement(26..319)
                     /gene="ybgE"
                     /locus_tag="IRB70_004839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyd operon protein YbgE"
                     /protein_id="HBC0634636.1"
                     /translation="MSKIIATLYAVMDKRPLRALSFVMALLLAGCMFWDPSRFAAKTS
                     ELEIWHGLLLMWAVCAGVIHGVGFRPQKVLWQGIFCPLLADIVLIVGLIFFFF"
     gene            complement(319..432)
                     /gene="cydX"
                     /locus_tag="IRB70_004840"
     CDS             complement(319..432)
                     /gene="cydX"
                     /locus_tag="IRB70_004840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_588444.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome bd-I oxidase subunit CydX"
                     /protein_id="HBC0634637.1"
                     /translation="MWYFAWILGTLLACSFGVITALALEHVESGKAGQEDI"
     gene            complement(447..1586)
                     /gene="cydB"
                     /locus_tag="IRB70_004841"
     CDS             complement(447..1586)
                     /gene="cydB"
                     /locus_tag="IRB70_004841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000568269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome d ubiquinol oxidase subunit II"
                     /protein_id="HBC0634638.1"
                     /translation="MIDYEVLRFIWWLLVGVLLIGFAVTDGFDMGVGMLTRFLGRNDT
                     ERRIMINSIAPHWDGNQVWLITAGGALFAAWPMVYAAAFSGFYVAMILVLASLFFRPV
                     GFDYRSKIEETRWRNMWDWGIFIGSFVPPLVIGVAFGNLLQGVPFNVDEYLRLYYTGN
                     FFQLLNPFGLLAGVVSVGMIITQGATYLQMRTVGELHLRTRATAQVAALVTLVCFALA
                     GVWVMYGIDGYVVKSTMDHYAASNPLNKEVVREAGAWLVNFNNTPILWAIPALGVVLP
                     LLTILTARMDKAAWAFVFSSLTLACIILTAGIAMFPFVMPSSTMMNASLTMWDATSSQ
                     LTLNVMTWVAVVLVPIILLYTAWCYWKMFGRITKEDIERNTHSLY"
     gene            complement(1602..3170)
                     /gene="cydA"
                     /locus_tag="IRB70_004842"
     CDS             complement(1602..3170)
                     /gene="cydA"
                     /locus_tag="IRB70_004842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415261.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome ubiquinol oxidase subunit I"
                     /protein_id="HBC0634639.1"
                     /translation="MLDIVELSRLQFALTAMYHFLFVPLTLGMAFLLAIMETVYVLSG
                     KQIYKDMTKFWGKLFGINFALGVATGLTMEFQFGTNWSYYSHYVGDIFGAPLAIEGLM
                     AFFLESTFVGLFFFGWDRLGKVQHMCVTWLVALGSNLSALWILVANGWMQNPIASDFN
                     FETMRMEMVSFSELVLNPVAQVKFVHTVASGYVTGAMFILGISAWYMLKGRDFAFAKR
                     SFAIAASFGMAAVLSVIVLGDESGYEMGDVQKTKLAAIEAEWETQPAPAAFTLFGIPD
                     QEEETNKFAIQIPYALGIIATRSVDTPVIGLKELMVQHEERIRNGMKAYSLLEQLRSG
                     STDQAVRDQFNSMKKDLGYGLLLKRYTPNVADATEAQIQQATKDSIPRVAPLYFAFRI
                     MVACGFLLLAIIALSFWSVIRNRIGEKKWLLRAALYGIPLPWIAVEAGWFVAEYGRQP
                     WAIGEVLPTAVANSSLTAGDLIFSMVLICGLYTLFLVAELFLMFKFARLGPSSLKTGR
                     YHFEQSSTTTQPAR"
BASE COUNT          966 a          924 c          827 g          679 t
ORIGIN      
        1 ataaattttt aaagagaatt ctgatttaaa agaagaagaa aatcagcccg acaatgagaa
       61 caatatcggc aagcaaaggg caaaaaatcc cttgccagag aaccttctgc ggacgaaagc
      121 ccacgccgtg aatcacacca gcacagacgg cccacatcag caataaacca tgccagattt
      181 ccagttcact ggtcttcgcg gcgaaacgtg atgggtccca aaacatacat cctgctaaca
      241 gaagcgccat cacgaaggaa agcgcccgca gggggcgctt gtccattacc gcatacaagg
      301 ttgcgataat cttactcatc agatgtcttc ttgaccggct ttgcctgatt cgacgtgctc
      361 aagcgccagc gcggtgatta ccccaaacga acaggcaaga agcgttccca gaatccatgc
      421 gaaataccac atttttagct ccttacttag tacagagagt gggtgttacg ttcaatatct
      481 tctttggtga tacgaccgaa cattttccag tagcaccagg cggtgtagag cagaatgatc
      541 ggtaccagaa ccaccgcaac ccaggtcatg acgttaagcg tcagctggct ggaagttgca
      601 tcccacattg tcagacttgc gttcatcatg gtgctggacg gcatcacaaa cgggaacatt
      661 gcgataccgg cagtcaggat gatgcaggcc agcgtcaggg aggagaacac aaacgcccac
      721 gcggctttat ccatacgtgc agtcaggatg gtcagcagcg gcagaaccac acccagtgcc
      781 ggaatagccc acagaattgg cgtgttgttg aagttaacca gccatgcgcc agcttcacga
      841 accacttctt tattcagcgg gttagaggct gcgtaatggt ccattgttga tttcacaaca
      901 taaccatcga taccgtacat cacccatacg ccagccagtg cgaagcagac cagtgtcacc
      961 agtgccgcca cctgagccgt tgcacgggta cgcaagtgca gttcacccac ggtacgcatt
     1021 tgcagatagg ttgcgccctg agtaatgatc atccctacgc tcaccacgcc tgccagcagg
     1081 ccgaacgggt taagcagctg gaaaaagtta ccggtgtagt acagacgcag atattcatca
     1141 acgttgaacg gtacgccctg caacaggtta ccgaacgcta caccaatcac cagcggcgga
     1201 acgaagctac caatgaagat gccccagtcc cacatgttac gccagcgggt ttcttcaatc
     1261 ttggagcggt agtcaaaacc gaccggacgg aagaacaaag acgccagcac gaggatcatc
     1321 gccacataga agccggagaa cgcagcggca tagaccatcg gccaggcagc aaagagtgcg
     1381 ccgcccgcgg tgatcagcca aacctggtta ccgtcccagt gtggtgcaat ggagttaatc
     1441 ataattcgac gctcggtgtc gttacgaccg aggaaacggg tgagcatgcc cacccccatg
     1501 tcgaaaccgt cagtgactgc aaaaccaatc agcagaacgc caaccagcag ccaccagata
     1561 aaacgcaata cttcataatc gatcatttga cgactcctgt cttagcgtgc cggctgagta
     1621 gtcgtggaag actgctcaaa gtgatagcga ccggttttca ggctgcttgg gccgaggcgt
     1681 gcaaacttga acattaagaa caattctgcc accaggaaca gggtatacag gccgcaaatc
     1741 agcaccattg agaagatgag atcgcctgcg gtcagtgacg agttcgccac agctgtcggc
     1801 agcacttcac cgatagccca cggttggcgg ccatattcag ccacaaacca gcccgcttct
     1861 acagcaatcc acggcagcgg aataccgtac agcgcggcgc gcagcagcca ttttttctcg
     1921 ccaatgcggt tgcggatgac actccagaaa gagagcgcga tgattgccag cagcaggaag
     1981 ccacacgcca ccataatacg gaacgcgaag tacagcggcg ctacacgcgg aatggagtct
     2041 ttggttgcct gttgaatctg cgcttcagtc gcatcagcca cgtttggcgt atagcgtttc
     2101 agcagcagac cgtaaccgag gtctttcttc atgctattga actggtcacg aaccgcctgg
     2161 tcggtagaac cagaacgcag ttgctcgagc agagagtacg ccttcatccc gttacgaatg
     2221 cgttcttcat gctgcaccat cagttctttc aggccgataa ctggagtatc cacggaacgc
     2281 gttgcaatga tgcccagcgc gtaagggatc tggatcgcaa atttgttcgt ctcctcttcc
     2341 tgatcaggaa tgccgaacag agtaaaggca gcaggcgcag gttgcgtttc ccactcggct
     2401 tcaatagcag ccagtttggt tttctgcacg tcgcccattt cgtaaccaga ttcatcaccc
     2461 agaacaataa cagacagaac ggcagccata ccgaagctgg cagcgatagc aaaggagcgt
     2521 ttagcgaagg cgaagtcacg acctttcagc atataccatg cgctgatacc gaggatgaac
     2581 atcgcgccag tcacataacc agacgctaca gtgtgaacga atttcacctg agcaaccggg
     2641 ttaagcacca gctcggagaa gctcaccatc tccatacgca tagtttcaaa gttgaaatcg
     2701 gacgcgattg ggttttgcat ccagccgttc gcaaccagaa tccacagtgc ggacaggttt
     2761 gaaccgagcg ccaccagcca ggtgacacac atatgctgaa ctttacccag acgatcccaa
     2821 ccgaagaaga acagacctac aaaggtggat tcgaggaaga aggccattag accttcgatt
     2881 gccagcggcg caccgaagat atcccctaca tagtgggaat agtaagacca gttagtcccg
     2941 aactggaact ccatggtcag accggtagcc acacccagag cgaagttgat accaaacaac
     3001 ttgccccaga acttggtcat atctttataa atctgtttgc cggaaaggac gtagaccgtt
     3061 tccataatgg ccagcaggaa cgccataccg agcgtcagtg gcacaaaaag gaagtggtac
     3121 atcgcggtca aggcaaactg taagcgcgac agttcgacta tatctaacat catgactcct
     3181 tgctcatcgc atgaagactc cgagagtgaa ccccgttaga aagggtcaca cgcatgcccc
     3241 aatacaaaat tatttgctcg cctctatcgt tgccatttca tcaaaagagg aaaagacaat
     3301 gataaaaaag ttacaaatat gttaatgaat aaaccaaatt gatcccgtaa ttatattacg
     3361 ccgcaaaatc cttacaataa acaggttttt attgag
//
LOCUS       DADXDL010000207         3365 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.208, whole genome shotgun sequence.
ACCESSION   DADXDL010000207 DADXDL010000000
VERSION     DADXDL010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3365
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.208"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..815
                     /locus_tag="IRB70_004843"
     CDS             <1..815
                     /locus_tag="IRB70_004843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HBC0634640.1"
                     /translation="KIHLYHCDHRGLPLALVSTEGATEWCAEYDEWGNLLNEENPHQL
                     QQLIRLPGQQYDEESGLYYNRHRYYDPLQGRYITQDPIGLKGGWNLYGYQLNPISDID
                     PLGLSMWEDAKSGACTNGLCGTLSAMIGPDKFDSIDSTAYDALNKINSQSICEDKEFA
                     GLICKDNSGRYFSTAPNRGERKGSYPFNSPCPNGTEKVSAYHTHGADSHGEYWDEIFS
                     GKDEKIVKSKDNNIKSFYLGTPSGNFKAIDNHGKEITNGKGLPNVCRVHGNM"
     gene            787..1170
                     /locus_tag="IRB70_004844"
     CDS             787..1170
                     /locus_tag="IRB70_004844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417940.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbbC/YhhH family protein"
                     /protein_id="HBC0634641.1"
                     /translation="MSAEFMVICKKIFFRNCVIVSLFVFTYNTWAQCNNNIKIMRKYE
                     SEGKYTVRNLVKNKAIALELAEIYVKNRYGQDAAEEEKPYKITELTTSWVVEGTIHSD
                     QIAGGVFIIEIGKNDGVILNFGHGK"
     gene            1275..2117
                     /locus_tag="IRB70_004845"
     CDS             1275..2117
                     /locus_tag="IRB70_004845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418051.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HEAT repeat domain-containing protein"
                     /protein_id="HBC0634642.1"
                     /translation="MSNTYQKRKASKEYGLYNQCKKLNDDELFRLLDDHNSLKRISSA
                     RVLQLRGGQDAVRLVIEFCSDKNYIRRDIGAFILGQIKICKKCEDNVFNILNNMALND
                     KSACVRATAIESTAQRCKKNPIYSPKIVEQSQITAFDKSTNVRRATAFAISVINDKAT
                     IPLLINLLKDPNGDVRNWAAFAININKYDNSDIRDCFVEMLQDKNEEVRIEAIIGLSY
                     RKDKRVLSVLCDELKKNTVYDDIIEAAGELGDKTLLPVLDTMLYKFDDNEIITSAIDK
                     LKRS"
     gene            2165..2710
                     /locus_tag="IRB70_004846"
     CDS             2165..2710
                     /locus_tag="IRB70_004846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HBC0634643.1"
                     /translation="MLDRLESEILADRVSEESRRWLASCGLTVEQMQNQMDPVFTPAR
                     KIHLYHCDHRGLPLALISKEGTTEWYAEYDEWGNLLNEENPHQLQQLIRLPGQQYDEE
                     SGLYYNRHRYYDPLQGRYITQDPIGLKGGWNFYQYPLNPTTTVDPLGLKFKVEGDRSA
                     FDSAIEYLKQDDEMKKNNYGP"
     gene            2778..3080
                     /locus_tag="IRB70_004847"
     CDS             2778..3080
                     /locus_tag="IRB70_004847"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634644.1"
                     /translation="MRIHWDPKAALLCTGVQKDGNFDFKNDNLEPVVALGHEIAHAEA
                     YLNEEFSVYMKRVNTPDPIYDNAEERRVITGIEKHVAQTLKQCVRKNHGGIIYHVP"
BASE COUNT         1133 a          566 c          770 g          896 t
ORIGIN      
        1 gaaaaatcca cctgtaccac tgcgaccatc gcggcctgcc gctggcgctt gtcagcacgg
       61 aaggggcaac agaatggtgc gcagaatacg atgagtgggg caacctgctg aatgaagaga
      121 acccgcacca gctgcaacag cttatccgcc tgccgggtca gcagtatgat gaggagtcag
      181 gcctgtatta caaccgccac cgctattatg acccgctgca ggggcggtat atcactcagg
      241 atccgattgg gctgaagggg ggatggaacc tgtatggata tcaattgaat ccgatatcag
      301 acatcgaccc cctgggttta tctatgtggg aggatgcaaa atcgggggca tgtactaatg
      361 gtctttgcgg cacactatcc gctatgatag gtccagataa gtttgattct atagatagca
      421 ccgcatatga cgccttaaat aaaataaata gccaatctat ttgcgaagat aaagagttcg
      481 ctggtttaat atgtaaggat aatagtggca gatatttctc aacagcacct aaccgagggg
      541 aaagaaaagg atcatatcca ttcaatagcc cttgccctaa tggtactgag aaagtatcag
      601 cttatcatac tcatggtgca gatagtcatg gagaatattg ggacgaaata ttttcaggca
      661 aagatgagaa aatagttaaa agtaaagata acaatatcaa gtcattttat ttgggcacgc
      721 ccagtggtaa ttttaaagca atagataacc acgggaagga aataacaaac ggaaaaggat
      781 tacctaatgt ctgcagagtt catggtaata tgtaaaaaaa tattttttag gaactgtgtc
      841 attgtatctt tgtttgtttt tacatacaac acatgggcgc agtgtaataa taatattaaa
      901 ataatgcgca agtatgaaag tgagggtaaa tataccgtta gaaatttggt taaaaataaa
      961 gctatagcat tggaattagc tgagatatat gttaagaatc gttatgggca ggatgccgca
     1021 gaagaagaaa aaccatataa aatcactgag ttaacaacaa gttgggttgt tgaaggcacc
     1081 attcactcag accaaattgc tggtggggtt tttattatag aaataggcaa aaatgatggg
     1141 gtaattctga attttggcca cggaaaataa gtatgtaagg ataatcaaac atcgtgtgcg
     1201 ctgatggcag agtaggtgga ggactccaga cagtcaaacg ataaaaaaag atagccttta
     1261 tggaggctcc tgcaatgtca aatacatacc agaaaagaaa ggcaagtaaa gagtatggtt
     1321 tatataatca atgtaagaaa ctaaatgatg atgaattatt tcgcttactt gatgatcaca
     1381 attccttgaa aaggatttca tctgccagag tattacagtt aagaggtggg caagacgctg
     1441 ttagattggt aattgagttc tgctctgata aaaattatat ccgtagagat atcggagcat
     1501 ttatactcgg gcaaataaaa atttgcaaaa aatgcgaaga taatgtgttt aatattttga
     1561 acaatatggc attgaatgat aagagcgctt gcgttcgagc tacggcaatc gagtcaacgg
     1621 ctcagcgatg caagaaaaac ccaatttatt cacctaaaat agtagaacaa tctcaaatta
     1681 ctgcttttga taaatcgact aatgtcagac gtgctacagc atttgctatt tctgttatca
     1741 atgataaagc aacaattcca ctattgatta atctgttaaa agatccaaat ggagatgtca
     1801 gaaactgggc cgcatttgca ataaatatca ataaatatga taatagtgat attagggatt
     1861 gttttgtgga gatgcttcag gataaaaatg aggaagtccg tattgaagca ataatcggac
     1921 tttcctacag aaaagataaa agggttttat ctgttttatg cgatgagtta aaaaaaaata
     1981 ctgtttatga tgatatcatt gaagctgcgg gtgaattagg tgataaaacg ctacttcctg
     2041 ttttagatac tatgttgtac aagtttgatg acaatgaaat tataacttcc gctattgata
     2101 agctgaagcg ttcatagcgt gagttgccta tgcacagtgg ggtattcccg ccggcacggt
     2161 gcagatgctc gatcggctgg aaagtgaaat cctggctgac cgggtgagtg aggaaagccg
     2221 ccgctggctg gcatcgtgcg gcctgacggt ggagcagatg caaaaccaga tggacccggt
     2281 gttcacgccg gcgcgaaaaa tccacctgta ccactgcgac catcgcggcc tgccgctggc
     2341 ccttatcagc aaggaaggga caacagaatg gtacgcagaa tatgatgaat ggggcaacct
     2401 gctgaatgaa gagaacccgc accagctgca acagctcatc cgcctgccgg gtcagcagta
     2461 tgatgaggag tccggcctgt attacaaccg ccaccgctat tatgacccgc tgcaggggcg
     2521 gtatatcact caggatccga ttgggctgaa ggggggatgg aatttttatc agtatccgtt
     2581 gaatccgacg acaacggttg atcctcttgg attaaaattt aaggtagaag gtgaccggtc
     2641 agcttttgat tctgcaattg aatatttgaa acaagatgat gagatgaaaa aaaataatta
     2701 cggcccttga aaaggataaa cacactatag tggttagttg taataataat tatgataact
     2761 catttaatcg atggacaatg agaatacact gggatcctaa agctgctcta ttgtgtacgg
     2821 gtgtacagaa agatggtaat tttgatttta aaaatgacaa tcttgagcct gtagtagcat
     2881 taggtcatga aatagcccat gcagaggctt atttaaatga agaattcagt gtttatatga
     2941 agcgagtaaa tacacctgat cctatatatg ataacgcaga ggaaagaaga gtaataacag
     3001 gtattgagaa acatgttgca caaacattaa aacaatgtgt tagaaaaaac cacgggggaa
     3061 taatttacca tgtaccttaa caatatacgg ttgtagttgc tatatttgta aagagatcac
     3121 cccatcgaac cggaataaat gaaaatgact atattttatg agttactatc atcattgaac
     3181 aatcagcata taagataacc tcaccaaaag cagtttaaac catggtaagt tgtagaagtg
     3241 gaaaattcgt cggcatagtt attttttgta acgaaaagat tatgagaaat tatttatatg
     3301 tttaattttg tttttatata ttagtatatt acacgcagaa agtgtaaaga aaatcagcac
     3361 attat
//
LOCUS       DADXDL010000208         3365 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.209, whole genome shotgun sequence.
ACCESSION   DADXDL010000208 DADXDL010000000
VERSION     DADXDL010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3365)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3365)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3365
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.209"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(118..690)
                     /locus_tag="IRB70_004848"
     CDS             complement(118..690)
                     /locus_tag="IRB70_004848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775089.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBC0634645.1"
                     /translation="MTKGIIGKALVKAVMSFRELYYTTINRIFLGLIWDLGKSCAFEG
                     AIYVPAVKGNVKVGDNVRFGPFVRIGATEGAKIIIGDNVSVNQGSFIISRESIVIGNN
                     TRVGEYVSIRDNDHEWRDKNTPILQQGFITNAVEIGSDVWIGRNVVISKGVKIGDGAV
                     IGANAVITKNVNQYEVVVGNPGRVIKVRGE"
     gene            complement(724..2145)
                     /gene="wbaP"
                     /locus_tag="IRB70_004849"
     CDS             complement(724..2145)
                     /gene="wbaP"
                     /locus_tag="IRB70_004849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014230067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-phosphate galactose
                     phosphotransferase WbaP"
                     /protein_id="HBC0634646.1"
                     /translation="MTLFSRNFIVSLSLAISDFVSLSCSIYIASALLLFITSNKAPLQ
                     NIDEWVLLHTILSVICIAWFSIRLRHYFYRKTFWLELKEILRTLVIFSVIEIAVMTFA
                     TWSFSRVLWIITWSSILLFVPLLRMLTKKILDTLDLWKRDTWIIGNGVNAIEAYKAIS
                     SENNLGLVVVGFISSNNDKNPAIDNINNVPVLEKNVSWLDTIDNKTQFIVAVEAHESE
                     IRNRWLRSFMIKGYRYVSVIPTLRGMPLDSTDMSFIFSHEVMIFRVQQNLAKLSSRIL
                     KRSFDIIGSTLIIAMISPLLIYISRKVKADGGPAIYGHERIGKGGRKFKCLKFRSMVI
                     NSQEVLSELLASSPEAKAEWDATFKLKEDPRITKIGNFLRRTSLDELPQLFNVLKGEM
                     SLVGPRPIITAELERYNEEVEYYLLSKPGMTGLWQVSGRSDVDYETRVYLDAWYVKNW
                     SMWNDIAILFKTITVVLKRDGAY"
     gene            complement(2229..>3365)
                     /locus_tag="IRB70_004850"
     CDS             complement(2229..>3365)
                     /locus_tag="IRB70_004850"
                     /EC_number="2.7.10.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis tyrosine autokinase"
                     /protein_id="HBC0634647.1"
                     /translation="LEKRKTLQDEKNKLNKRVSAMPSTQQEILRLSRDVESGRAIYMQ
                     LLNRQQELSIAKSSAIGNVRIIDKAITQTKPIKPKKVVIVLSGILIGIIFSVIIVLLR
                     VFLRRGIESPEQLEEQGINVYASIPVSEEFAHNILKKNKAGTKKNVEYAHFLAVENPA
                     DLAIESIRGLRTSLHFAMMEARNNILMISSASPNAGKTFVSSNLAAVISQTGKKVLFI
                     DADMRKGYTHKLFKASNENGLSDYLSGKVELQNIIQKIPVGDFDFIPRGIVPPNPAEL
                     LMHRRFGELTNWANEHYDIVIMDTPPVLAVTDAAIIGNYVGTTLLIVRFEQNTVKEIE
                     VSIKRFEQSGVIVKGCILNGVVKKVSSYYGYGYQHYGYSYSDDK"
BASE COUNT         1061 a          718 c          468 g         1118 t
ORIGIN      
        1 taatatttgc aacttccggc gttaagcctt taaatgccaa aaatagggtt aatagaaaaa
       61 aaacaccttg tcccataatg gggcctgaag caatgtgtat aaatttttta aacaaattta
      121 ttcacctcta acttttataa cacggccagg atttccgact actacctcgt attggtttac
      181 attttttgtt ataaccgcat tagcgccaat gacggcgcca tctcctattt taaccccttt
      241 actaatcact acatttcttc caatccaaac atcacttcca atctcaacag catttgtaat
      301 gaatccttgc tgtaaaatcg gcgtattttt atctctccat tcatgatcat tatcacggat
      361 tgaaacatat tctccaaccc gcgtattatt cccaataact atagattccc tagatataat
      421 aaagcttcct tgattaacgc tgacattatc accaataatt atttttgccc cttctgtagc
      481 accaattcta acaaacggac cgaatctaac attatcgcct acttttacat ttcctttgac
      541 tgctggtaca tatatagcac cttcaaaagc acaagactta ccaagatccc agattaaccc
      601 taagaagatt cgattaatag ttgtataata taattctcga aaagacatta ctgccttaac
      661 aagggctttg cctataatcc ctttagtcat atttgatacc gctcatcaaa aggttaatta
      721 ttattaatat gcaccatctc gttttaagac aacggtaatc gttttaaata atatcgctat
      781 atcattccac atagaccagt tcttaacata ccaagcatcc agatatactc ttgtctcata
      841 atcaacatcg cttcgcccac taacctgcca taaacctgtc attccgggtt tgctcaagag
      901 ataatattcc acttcctcat tatatctttc aagttctgca gtaattattg gcctaggacc
      961 aactaaactc atttcaccct ttagaacatt aaacaattga ggcagttcat caagactggt
     1021 tcttctcaga aaattcccaa ttttagttat acgtgggtcc tcttttaatt taaatgtggc
     1081 atcccattca gcctttgctt cggggctgga ggctaataat tcactcaata cttcttgaga
     1141 attaataacc attgagcgaa atttcaggca tttaaattta cgacctcctt tcccaatcct
     1201 ttcatgccca tatattgctg gcccaccatc cgctttaact ttcctactaa tatatattag
     1261 caatggggat atcattgcta taattagcgt ggatccaata atatcaaatg accgttttaa
     1321 aatacgagag gataatttgg caagattttg ttgcacacgg aaaatcatta cctcatgact
     1381 aaaaataaat gacatatctg tactatctaa tggcatccct ctcagagtag gtataaccga
     1441 tacataacga tagcctttaa tcatgaaact tctcagccaa cgattccgta tttcactttc
     1501 atgtgcttcc acagcaacaa taaattgtgt tttgttatca atcgtatcaa gccatgatac
     1561 atttttttcc aggactggga cattattaat attgtcaatt gcaggattct tatcattatt
     1621 ggaggaaata aaaccaacaa ctaccaaccc taaattattc tcactactaa ttgctttata
     1681 tgcttcaatg gcattaaccc catttcctat aatccatgta tctcgtttcc ataagtctaa
     1741 agtatccaat attttttttg ttaacatgcg caaaagaggc acaaataata gaatgctact
     1801 ccatgttatt atccacagaa ctctagaaaa cgaccatgtt gcaaaggtca taacagctat
     1861 ctctatcaca gaaaagatga ctaaagttct taagatttct ttgagttcaa gccaaaatgt
     1921 tttccgataa aaataatgtc ttagcctaat tgaaaaccat gcaatacaaa taactgataa
     1981 gatagtatgt aataaaaccc attcatctat attttgcaat ggagccttat ttgaagttat
     2041 aaatagtaat aatgcagaag cgatatagat cgagcaagaa agacttacaa agtcagaaat
     2101 tgccagagat aaactgacga taaaatttct agaaaaaagt gtcatttttt cctcacgtgt
     2161 tgacgcgatt attcttctca aaaatagtat ataacaaggc agtctgtctg ccttgtcgtt
     2221 tttaagtcct atttatcgtc agaatatgaa tagccataat gttgatagcc ataaccgtaa
     2281 taactgctta ctttttttac cacgccattt aggatacagc cttttacaat aacgccactt
     2341 tgttcaaatc tcttaatact cacttcaatt tctttaacag tattctgttc aaaacgaact
     2401 ataagtaaag tagtccctac ataattgcca ataatcgctg catctgttac tgctaaaact
     2461 ggcggggtgt ccataattac gatatcgtaa tgctcattag cccagtttgt taattcacca
     2521 aatcgcctat gcattaacaa ctctgcagga ttaggtggaa caatgcctct tggtatgaaa
     2581 tcaaagtctc ctacagggat tttctgaata atattttgca gttcgacttt cccagataaa
     2641 taatctgata atccattttc attactcgct ttaaatagct tatgcgtgta tccctttcgc
     2701 atatccgcat caataaacag gacttttttg ccagtctgag atataactgc tgctaaattt
     2761 gaactaacaa aagttttacc agcattcgga ctagcactag agatcattaa tatattattt
     2821 ctagcttcca tcattgcaaa atgaaggctg gtgcgtaatc ctcttattga ttcaattgcc
     2881 aaatctgcag gattttctac agccaggaaa tgagcatatt caacattctt cttagttcct
     2941 gctttatttt ttttcagtat attatgagca aattcctcgg acacaggtat actagcataa
     3001 acattgatac cctgctcctc caattgttct ggagattcga taccacgtct taaaaacaca
     3061 cgcaacaata caattatgac tgaaaatatg atacctatta atattcccga taaaactata
     3121 acgacctttt tcggttttat tggttttgtc tgagtaatcg ctttatctat aattcgtacg
     3181 ttaccgattg cgctagattt agcaatgctc aactcctgtt gccgattgag cagttgcata
     3241 tatatcgctc gacctgactc tacatctcta ctcaaccgaa gaatttcttg ttgtgtagaa
     3301 ggcattgcag aaacccgttt atttaattta ttcttctcat cttgtaacgt ttttcttttt
     3361 tctaa
//
LOCUS       DADXDL010000209         3353 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.210, whole genome shotgun sequence.
ACCESSION   DADXDL010000209 DADXDL010000000
VERSION     DADXDL010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3353)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3353)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3353
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.210"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            244..1926
                     /locus_tag="IRB70_004851"
     CDS             244..1926
                     /locus_tag="IRB70_004851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310130.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase"
                     /protein_id="HBC0634648.1"
                     /translation="MKSALKKSVVSTSISLILASGMAAFAAHAADDVKLKATKTNVAF
                     SDFTPTEYSTKGKPNIIVLTMDDLGYGQLPFDKGSFDPKTMENREVVDTYKIGIDKAI
                     EAAQKSTPTLLSLMDEGVRFTNGYVAHGVSGPSRAAIMTGRAPARFGVYSNTDAQDGI
                     PLTETFLPELFQNHGYYTAAVGKWHLSKISNVPVPEDKQTRDYHDNFTTFSAEEWQPQ
                     NRGFDYFMGFHAAGTAYYNSPSLFKNRERVPAKGYISDQLTDEAIGVVDRAKTLDQPF
                     MLYLAYNAPHLPNDNPAPEQYQKQFNTGSQTADNYYASVYSVDQGVKRILEQLKKNGQ
                     YDNTIILFTSDNGAVIDGPLPLNGAQKGYKSQTYPGGTHTPMFMWWKGKLQPGNYDKL
                     ISAMDFYPTALDAADISIPKDLKLDGVSLLPWLQDKKQGEPHKNLTWITSYSHWFDEE
                     NIPFWDNYHKFVRHQSDDYPHNPNTEDLSQFSYTVRNNDYSLVYTVENNQLGLYKLTD
                     LQQKDNLAAANPQVVKEMQGVVREFIDSSQPPLSEVNQEKFNNIKKALSEAK"
     gene            1978..3135
                     /locus_tag="IRB70_004852"
     CDS             1978..3135
                     /locus_tag="IRB70_004852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416014.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic sulfatase maturase"
                     /protein_id="HBC0634649.1"
                     /translation="MHVTAKPSSFQCNLKCDYCFYLEKESQFTHEKWMDDSTLKEFIK
                     QYIAASGNQVYFTWQGGEPTLAGLDFFRKVIHYQQRYAGQKRIFNALQTNGILLNNEW
                     CAFLKEHEFLVGISIDGPQELHDRYRRSNSGNGTFAKVIAAIERLKSYQVEFNTLTVI
                     NNVNVHYPHEVYHFLKSIGSKHMQFIELLETGTPNIDFSGHSENTFRIIDFSVPPTAY
                     GKFMSTIFMQWVKNDVGEIFIRQFESFVSRFLGNGHTSCIFQESCKDNLVVESNGDIY
                     ECDHFVYPQYKIGNINKSELKTMNSVQLTAQKKRISAKCQQCAYKPICNGGCPKHRIT
                     KVNNETVSYFCEGYKILFSTMVPYMNAMVELAKNRVPLYHIMDVAKQMENN"
     gene            complement(3101..3226)
                     /locus_tag="IRB70_004853"
     CDS             complement(3101..3226)
                     /locus_tag="IRB70_004853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634650.1"
                     /translation="MKTKHPTGIYVGCLVKVIRRRLRMELRGSVINYSPFVLQHP"
BASE COUNT         1024 a          709 c          667 g          953 t
ORIGIN      
        1 tatgatctca attcggtatt ttgtcggtga aattaaataa tttgttaaat atcaatagat
       61 tagttgttta tcaacgagaa attacttagt agaacagaaa gtaatgtcaa cagtttatgg
      121 actgttattt ctcttttttt agctaaatct gctatctctt tatgtgactc acttcactta
      181 catccactta tttctcttcg taaaattact ttggaattaa gtacaataag aagaggaaca
      241 tttatgaagt ctgcattaaa gaaaagtgtc gtaagtacct cgatatcttt gatactggca
      301 tctggtatgg ctgcatttgc tgctcatgcg gcagatgatg taaagctgaa agcaaccaaa
      361 acaaacgttg ctttctcaga ctttacgccg actgaataca gtaccaaagg aaagccaaat
      421 attatcgtac tgaccatgga tgatcttggt tatggacaac ttccttttga taagggatct
      481 tttgacccaa aaacaatgga aaatcgtgaa gttgtcgata cctacaaaat agggatagat
      541 aaagccattg aagctgcgca aaaatcaacg ccgacgctcc tttcattaat ggatgaaggc
      601 gtacgtttta ctaacggcta tgtggcgcac ggtgtttccg gcccctcccg cgccgcaata
      661 atgaccggtc gagcgcccgc ccgctttggt gtctattcca ataccgatgc tcaggatggt
      721 attccgctaa cagaaacttt cttgcctgaa ttattccaga atcatggtta ttacactgca
      781 gcagtaggta aatggcactt gtcaaaaatc agtaatgtgc cggtaccgga agataaacaa
      841 acgcgtgact atcatgacaa cttcaccaca ttttctgcgg aagaatggca acctcaaaac
      901 cgtggctttg attactttat gggattccac gctgcaggaa cggcatatta caactcccct
      961 tcactgttca aaaaccgtga acgcgtccca gcaaaaggtt atatcagcga tcagttaacc
     1021 gatgaggcaa ttggcgttgt tgatcgtgcc aaaacacttg accagccttt tatgctttac
     1081 ctggcttata atgctccgca cctgccaaat gataatcctg caccggagca atatcagaag
     1141 caatttaata ccggtagtca aacagcagat aactactacg cttccgttta ttctgttgat
     1201 cagggtgtaa aacgcattct cgaacaactg aagaaaaacg gacagtatga caatactatt
     1261 attctcttta cctccgataa tggtgcggtt atcgatggtc ctctgccgct gaacggggcg
     1321 caaaaaggct ataagagtca gacttatcct ggcggtactc acaccccaat gtttatgtgg
     1381 tggaaaggaa aacttcaacc cggtaattat gacaagctga tttccgcaat ggatttctac
     1441 ccgacagctc ttgatgcagc cgatatcagc attccaaaag accttaagct ggatggcgtt
     1501 tccttgctgc cgtggttgca agataagaaa caaggcgagc cacataaaaa tctgacctgg
     1561 ataacctctt attctcactg gtttgatgag gaaaatattc ccttctggga taattaccac
     1621 aaatttgtcc gccatcagtc agacgattac ccgcataacc ccaacaccga ggatttaagc
     1681 caattctctt atacggtgag aaataacgat tattcgctag tctatacagt agaaaacaat
     1741 cagttaggtc tatacaaact gacggatcta cagcaaaaag ataaccttgc ggccgccaat
     1801 ccgcaggtcg ttaaagagat gcaaggcgtg gtaagagagt ttatcgacag cagccaacca
     1861 ccgcttagcg aggtaaatca ggagaagttt aacaatatca agaaagcact aagcgaagcg
     1921 aaataactaa accttcatgc ggcggatttt tccgccgcct tattgagcga gatagcgatg
     1981 cacgttacag ccaagccctc cagttttcaa tgtaatctca aatgtgatta ctgtttttac
     2041 cttgaaaaag agtcgcagtt tactcatgaa aaatggatgg atgacagcac tctgaaagag
     2101 ttcatcaaac aatatatcgc agcgtctggc aatcaggtct attttacctg gcaagggggt
     2161 gaacccactc tggctggcct ggattttttc cgtaaagtta ttcactatca acaacgctat
     2221 gcaggccaaa aacgtatttt taatgcatta caaacgaatg gcattttatt gaataatgaa
     2281 tggtgtgcct ttctcaaaga acatgagttt ctggttggta tctcgatcga tggcccccag
     2341 gagctacatg accgttacag acgcagtaat tcaggcaacg gtacttttgc aaaagtgata
     2401 gcagccatcg agcgtctgaa atcatatcaa gtagagttta atacgttaac cgtcattaat
     2461 aacgttaatg tccattaccc tcatgaggtt tatcattttt taaaatctat cggcagtaaa
     2521 catatgcaat ttatcgaatt gctagaaacc gggacgccga atattgattt cagtggccat
     2581 agtgagaaca cattccgtat cattgatttt tctgtgcctc ccacggctta tggcaagttt
     2641 atgtcaacca tttttatgca atgggttaaa aacgatgtgg gtgaaatttt catccgtcag
     2701 tttgaaagct ttgtcagccg ttttttgggg aatgggcata ccagttgtat tttccaggaa
     2761 tcctgcaagg ataatctggt tgttgaaagt aatggagata tttacgaatg cgatcatttt
     2821 gtctatccac agtacaaaat tggaaacatt aataaatctg aactcaaaac gatgaacagt
     2881 gttcaactga cagcgcaaaa aaaacggatt tcagcgaaat gtcagcaatg tgcatataaa
     2941 cctatctgca atggtggttg ccctaagcat cgtattacta aagtaaacaa tgagactgtt
     3001 tcctattttt gcgaaggtta taaaatcctt ttttcaacca tggtacctta tatgaacgcc
     3061 atggtggagt tagctaagaa cagagtaccg ctttaccaca ttatggatgt tgcaaaacaa
     3121 atggagaata attaataacg ctccccctta gctccattct tagcctcctt cttatgacct
     3181 taacaaggca cccgacataa attcctgtcg ggtgtttcgt cttcatcatc ttcctttgcg
     3241 aaaatcctgg cttacgaggt atgcgtcagg gcattagcaa tacccttgat tatcaatagc
     3301 ataaccataa ccactgaaaa tgaaatattt ctttatattt catattgtta aat
//
LOCUS       DADXDL010000210         3284 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.211, whole genome shotgun sequence.
ACCESSION   DADXDL010000210 DADXDL010000000
VERSION     DADXDL010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3284
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.211"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            44..1255
                     /gene="bluF"
                     /locus_tag="IRB70_004854"
     CDS             44..1255
                     /gene="bluF"
                     /locus_tag="IRB70_004854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="blue light-responsive regulator BluF"
                     /protein_id="HBC0634651.1"
                     /translation="MLTTLIYRSHIRDDEPVKKIEEMVSIANRRNMLSDVTGILLFNG
                     SHFFQLLEGPEEQVKMIYRAICQDPRHYNIVELMCDYAPARRFGKAGMELFDLRLHER
                     DDVLQAVFDKGTSKFQLTYDDRALQFFRTFVLATEQATYFEIPAEDSWLFIADGSDKE
                     LDSCTLSPTINDHFAFHPIVDPLSRRIIAFEAIVQKNEDSPSAIAVGQRKDGEIYTAD
                     LKSKALAFAMAHALELGDKMISINLLPMTLVNEPDAVSFLLDEIKANALVPEQIIVEF
                     TESEVISRFDEFAEAIKSLKAAGISVAIDHFGAGFAGLLLLSRFQPDRIKISQELITN
                     VHKSGPRQAIIQAIIKCCTSLEIQVSAMGVTTPEEWMWLESAGIEMFQGDLFAKAKLN
                     GIPSVAWPEKK"
     gene            1460..2191
                     /gene="bluR"
                     /locus_tag="IRB70_004855"
     CDS             1460..2191
                     /gene="bluR"
                     /locus_tag="IRB70_004855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional repressor BluR"
                     /protein_id="HBC0634652.1"
                     /translation="MAYYSIGDVAERCGINPVTLRAWQRRYGLLKPQRSEGGHRLFDE
                     EDIQRIEEIKRWISNGVPVGKVKALLETTSQDTEDDWSRLQEEMMSILRMANPAKLRA
                     RIISLGREYPVDQLINHVYLPVRQRLVLDHNTSRIMSSMFDGALIEYAAASLFEMRRK
                     PGKEAILMAWNVEERARLWLEAWRLSLSGWHISVLADPIESPRPELFPTQTLIVWTGM
                     APTRRQNELLQHWGEQGYKVIFHAP"
     gene            2412..2816
                     /locus_tag="IRB70_004856"
     CDS             2412..2816
                     /locus_tag="IRB70_004856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1398 domain-containing protein"
                     /protein_id="HBC0634653.1"
                     /translation="MDQVVVFQKMFEQVRKEQNFSWFYSELKHHRIAHYIYYLATDNI
                     RIITHDDTVLLLRGTRNLLKVSTTKNPAKIKEAALLHICGKSTFREYCSTLADAGVFR
                     WVTDVNHNKRSYYAIDNTLLYIEDVENNKPLI"
     gene            2869..2979
                     /locus_tag="IRB70_004857"
     CDS             2869..2979
                     /locus_tag="IRB70_004857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634654.1"
                     /translation="MEIKVQRLSLWMINTVFLLPPINNHQANTINLIFEM"
     gene            3216..3260
                     /locus_tag="IRB70_004858"
     CDS             3216..3260
                     /locus_tag="IRB70_004858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_009518766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634655.1"
                     /translation="MFSKLAQSSIKAMF"
BASE COUNT          977 a          683 c          683 g          941 t
ORIGIN      
        1 gttaccgtct tactctcgcc tctcccatta ccctggacag ttaatgctta ccacccttat
       61 ttatcgtagc catatacgtg acgacgaacc tgtcaaaaaa atcgaagaaa tggtttcgat
      121 agcaaatcgc aggaacatgc tgtctgacgt aacagggatc ttactgttta atggttctca
      181 ttttttccag cttctggaag gtccggaaga acaggttaaa atgatatatc gggctatatg
      241 ccaggatcca cggcactata atattgttga gctgatgtgc gattacgcgc ctgctcgccg
      301 ttttggcaaa gcgggaatgg aattatttga tttgcgcctg cacgagcgag atgacgtttt
      361 acaggccgta ttcgacaaag gcacatcaaa atttcagcta acttatgatg acagagcgct
      421 acaatttttt cgtacttttg tccttgcaac cgaacaagca acctatttcg agatccctgc
      481 cgaagactcc tggcttttta tcgctgacgg atctgataaa gaacttgatt cctgtaccct
      541 ttcaccaact ataaacgacc actttgcctt tcatcctatt gtcgatccct tatcgcggcg
      601 gataatcgct tttgaagcca ttgtgcaaaa aaatgaagat agcccatcag ctatagcggt
      661 tgggcagcgt aaagacgggg aaatctatac agcggatctc aaaagtaagg cgcttgcatt
      721 cgcgatggca cacgcacttg agctcggtga taaaatgatt tcaatcaatc tattacctat
      781 gaccctggtt aacgaacctg acgcagtctc ttttttactt gatgaaataa aggccaatgc
      841 tctggtgcct gaacaaatca tcgttgaatt tactgaaagt gaagtcatat ctcggtttga
      901 tgagtttgca gaagcgatta aatcgcttaa ggctgccggt atcagtgtag caattgatca
      961 ttttggcgca ggttttgccg gtttgttact cctgtcacgc ttccagcctg acagaattaa
     1021 aatcagtcag gaattgatta ccaatgttca taaaagcggg ccacggcagg caattattca
     1081 agcgatcata aaatgctgta catcacttga aattcaagtc tctgctatgg gtgtgacaac
     1141 accagaagag tggatgtggc ttgaatctgc aggaattgag atgtttcagg gagatctgtt
     1201 tgcgaaagct aaattgaatg gtatcccttc agttgcgtgg ccggagaaaa aataatttcc
     1261 agcacattat ttcgtatgat ttctgaaaat catcgtgaaa atgaatacgt tatgtttaaa
     1321 tttaatccac attaaaaata atgtttcatt caatttagct gaaatcttat ttatactttg
     1381 tacaatttta gcgtatattg tacaaagtat tattgggtcg tgtacaggcg acggagattt
     1441 gtgaccgcaa ggaggaattg tggcttatta cagcattggt gatgttgctg aacgttgcgg
     1501 gattaatcct gtcactctcc gggcctggca acgccgctac ggtttgttaa aaccacagcg
     1561 cagtgaaggc ggacaccgac tctttgatga agaagacata caacgcatcg aagagatcaa
     1621 gcgttggata agtaatggcg tccctgtagg caaagttaaa gcattactgg aaaccaccag
     1681 ccaggatacg gaagatgact ggagccgcct gcaagaagag atgatgtcaa ttcttcgtat
     1741 ggctaatcct gccaaactac gcgcgagaat tatttcactg ggccgagagt acccagtaga
     1801 tcaattgatt aatcatgttt accttcctgt tcgccagcgt ctcgtgcttg atcacaacac
     1861 ctcccgcatt atgagcagta tgtttgacgg cgcattaatt gaatacgcag cagcctcgct
     1921 tttcgaaatg cgccgtaagc ccggtaaaga agccattctg atggcgtgga atgttgaaga
     1981 gagagcacga ttgtggctgg aagcatggcg tttatcattg tcaggatggc acatttctgt
     2041 tcttgctgat cccattgaat cgccgcgccc ggaactgttc ccgacgcaaa cattaattgt
     2101 ctggacaggc atggcaccaa cgagaaggca aaacgaactt ttacaacact ggggtgagca
     2161 aggttataaa gtcatcttcc atgcccccta atttcacctt tatcccgccc cttagacaga
     2221 atgttataat ctgaacccac aacagcgttt gtaccggagc tggtccatta caaaatgctc
     2281 accgggagaa ttcaggtaat ccccctttca cactttgtac atatcacagc caaaggacag
     2341 accagattga agtggtaaaa ccgatcgtgc acactacgca gtctcacaac taacaagagg
     2401 ttattatcct gatggatcag gtcgttgttt ttcaaaagat gtttgagcaa gtgagaaaag
     2461 agcaaaactt ctcctggttt tattcagaat taaaacatca ccgtattgca cattacattt
     2521 attatctagc tacggataac atcagaatta ttactcacga tgacacggtt ttgttattaa
     2581 gaggaaccag gaacctgtta aaagttagta cgaccaagaa ccctgctaaa ataaaagagg
     2641 ccgcattgct tcatatttgc ggaaaatcta catttcggga atactgttca acactggcag
     2701 acgcgggcgt tttccggtgg gttactgatg ttaatcataa caaacgcagt tactacgcca
     2761 ttgataatac gcttttatat attgaagatg tagaaaacaa taaaccatta atctagctaa
     2821 agttggaagc ttaagaaatg cttcataatt cagtaaggca ttagcataat ggaaataaaa
     2881 gtgcagagac tatccctatg gatgataaat actgtctttt tattgccacc cataaataat
     2941 caccaggcca atactatcaa cttaatattt gaaatgtgat cacttgactt tctatacgtt
     3001 attttataac ggttaacata tttataaaac caacgggcgt gccatacgcc cgtttcaata
     3061 cttaacgcac atgtgttttg gtttagtcat catccgatta tatgtatttt agtcaggaac
     3121 gggtttaacc atttttatat aactaaaaaa ttgaaacctt attctcaggt catgcttata
     3181 ttcatcatta tcgttatatt aaaaggccaa ccataatgtt tagcaaattg gctcaaagta
     3241 gcataaaggc tatgttttaa ttacagaata ttcagtcatt tgaa
//
LOCUS       DADXDL010000211         3223 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.212, whole genome shotgun sequence.
ACCESSION   DADXDL010000211 DADXDL010000000
VERSION     DADXDL010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3223)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3223)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3223
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.212"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            127..1101
                     /gene="hemB"
                     /locus_tag="IRB70_004859"
     CDS             127..1101
                     /gene="hemB"
                     /locus_tag="IRB70_004859"
                     /EC_number="4.2.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308450.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="porphobilinogen synthase"
                     /protein_id="HBC0634656.1"
                     /translation="MTDLIQRPRRLRKSPALRAMFEETTLSLNDLVLPIFVEEEIDDY
                     KAVEAMPGVMRIPEKHLAREIERIANAGIRSVMTFGISHHTDETGSDAWREDGLVARM
                     SRICKQTVPEMIVMSDTCFCEYTSHGHCGVLCEHGVDNDATLENLGKQAVVAAAAGAD
                     FIAPSAAMDGQVQAIRQALDAAGFKDTAIMSYSTKFASSFYGPFREAAGSALKGDRKS
                     YQMNPMNRREAIRESLLDEAQGADCLMVKPAGAYLDIVRELRERTELSIGAYQVSGEY
                     AMIKFAALAGAIDEEKVVLESLGSIKRAGADLIFSYFALDLAEKKILR"
     gene            complement(1141..1992)
                     /gene="tauD"
                     /locus_tag="IRB70_004860"
     CDS             complement(1141..1992)
                     /gene="tauD"
                     /locus_tag="IRB70_004860"
                     /EC_number="1.14.11.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine dioxygenase"
                     /protein_id="HBC0634657.1"
                     /translation="MSERLSITPLGPYIGAQISGADLTRPLSDNQFEQLYHAVLRHQV
                     VFLRDQAITPQQQRALAQRFGELHIHPVYPHAEGVDEIIVLDTHNDNPPDNDNWHTDV
                     TFIETPPAGAILAAKELPSTGGDTLWTSGIAAYEALSVPFRQLLSGLRAEHDFRKSFP
                     EYKYRKTEEEHQRWREAVAKNPPLLHPVVRTHPVSGKQALFVNEGFTTRIVDVSEKES
                     EALLGFLFAHITKPEFQVRWSWQPNDIAIWDNRVTQHYANADYLPQRRIMHRATILGD
                     IPFYRAG"
     gene            complement(1989..2816)
                     /gene="tauC"
                     /locus_tag="IRB70_004861"
     CDS             complement(1989..2816)
                     /gene="tauC"
                     /locus_tag="IRB70_004861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter permease TauC"
                     /protein_id="HBC0634658.1"
                     /translation="MSVLINEKLHSHRLKWRWPLSRQVTLSIGTLAVLLTVWWAVAAL
                     QLISPLFLPPPQQVLAKLLTIAGPQGFMDATLWQHLAASLTRILLALLAAVLIGIPVG
                     IAMGLSPTVRGILDPIIELYRPVPPLAYLPLMVIWFGIGETSKILLIYLAIFAPVAMS
                     ALAGVKSAQQVRIRAAQSLGASRAQVLWFVILPGALPEILTGLRIGLGVGWSTLVAAE
                     LIAATRGLGFMVQSAGEFLATDVVLAGIAVIAIIAFLLELGLRALQRRLTPWHGEVQ"
     gene            complement(2813..>3223)
                     /locus_tag="IRB70_004862"
     CDS             complement(2813..>3223)
                     /locus_tag="IRB70_004862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBC0634659.1"
                     /translation="GAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFT
                     RDQMQTLLLKLWQETGKQVLLITHDIEEAVFMATELVLLSSGPGRVLERLPLNFARRF
                     VAGEPSRSIKSDPQFIAMREYVLSRVFEQREAFS"
BASE COUNT          760 a          942 c          850 g          671 t
ORIGIN      
        1 tattacaaag atgtcctggc ctctcattca ttctcttctt gtcaacatcg cgacaacttt
       61 cgtaaaacat ccccaccctg cttcaggtat actatgcccc tcgattccac aaacatcagg
      121 cagaccatga cagacttaat ccaacgccct cgtcgcctgc gcaaatctcc tgcgctgcgc
      181 gctatgtttg aagagacaac acttagcctt aacgacctgg tgttgccgat ctttgttgaa
      241 gaagaaattg acgactacaa agccgttgaa gccatgccag gcgtgatgcg cattccagag
      301 aaacatctgg cacgcgaaat tgaacgcatc gccaacgccg gtattcgttc cgtgatgact
      361 ttcggcatct ctcaccatac cgatgaaacc ggcagcgatg cctggcggga agatggtctg
      421 gtggcgcgta tgtcgcgcat ctgcaagcag accgtgccag aaatgatcgt catgtcagac
      481 acctgtttct gtgaatacac ttctcacggt cactgcggtg tgctgtgcga gcatggcgtc
      541 gacaacgacg cgaccctgga aaatttaggc aagcaggccg tggttgcagc tgctgcaggt
      601 gcagacttca tcgccccttc cgccgcaatg gatggccagg tacaagcgat tcgccaggcg
      661 ctggacgctg cgggctttaa agatacggcg attatgtcgt attcgaccaa gttcgcctcc
      721 tccttttatg gcccgttccg tgaagctgcc ggaagcgcat taaaaggcga ccgcaaaagc
      781 tatcagatga acccaatgaa ccgtcgtgag gcgattcgtg agtcactgct ggatgaagcc
      841 cagggcgcag actgcctgat ggttaaacct gctggagcgt acctcgacat cgtgcgtgag
      901 ctgcgtgaac gtactgaatt gtcgattggc gcgtatcagg tgagcggtga gtacgcgatg
      961 attaagttcg ccgcgctggc gggtgctata gatgaagaga aagtcgtgct cgaaagctta
     1021 ggttcaatta agcgtgcggg tgcggatctg attttcagct actttgcgct ggatttggct
     1081 gagaagaaga ttctgcgtta atgatcatta tgccgggtta tccaacccgg catttccccc
     1141 ttaccccgcc cgataaaacg gaatatcccc aagaatcgtc gcccgatgca taatccgccg
     1201 ctgtggcagg taatccgcat tggcatagtg ctgagtcaca cggttatccc aaatcgcaat
     1261 atcattcggt tgccagctcc agcgcacctg aaactccggt ttggtgatat gggcaaacaa
     1321 aaaacctaac aaggcttcgc tctctttctc gctgacatca acaattcgcg tggtaaagcc
     1381 ttcattcaca aacagcgcct gtttaccgct caccggatgc gttcgcacca ccggatgtag
     1441 caacggcgga tttttcgcga ccgcctcgcg ccagcgttga tgctcctcct cggttttgcg
     1501 gtatttgtat tccgggaacg atttacggaa atcatgctcc gcacgcaacc cgctcagcag
     1561 ctggcggaag ggaacagaga gcgcctcata ggccgcaata ccgctggtcc agagcgtatc
     1621 gccgccggtc gagggtaact cttttgccgc cagaatcgcc cctgcgggtg gcgtttcaat
     1681 aaatgtcaca tcggtatgcc agttgtcgtt atccggcgga ttatcgttat gagtatccag
     1741 gacgatgatc tcgtcaaccc cttcggcatg agggtaaaca ggatgaatat gcagttcgcc
     1801 aaaacgttgg gccagcgcgc gttgctgctg cggcgtaata gcttgatcgc gcagaaacac
     1861 cacctgatgg cgcagcaccg catggtaaag ctgttcaaac tgattatcgc ttaacgggcg
     1921 cgtcaggtcg gcacccgaaa tttgtgcgcc aatatacggc cccagcgggg taatgctcag
     1981 acgttcactc attgtacttc tccatgccag ggcgtcaggc ggcgctgtaa cgcgcgcaaa
     2041 cccagttcta aaagaaaagc gataatcgca atcaccgcga tccccgccag caccacgtca
     2101 gtcgcgagaa attcacccgc tgactgaacc ataaatccta aaccgcgcgt cgcggcaatc
     2161 agctccgccg ctaccagcgt agaccagccc acacccagac caatgcgtaa tccggtgagg
     2221 atttccggca gcgcgccggg caaaatgaca aaccacagca cctgcgcacg actggcaccc
     2281 agcgactggg cggcacgaat gcgaacctgc tgcgcgcttt tcacccccgc cagcgccgac
     2341 atcgccaccg gtgcaaaaat cgctaaatag atcagtaaga tcttcgaggt ttcgccaata
     2401 ccaaaccaga tcaccatcag cggcaaataa gccagcggcg gcaccggacg ataaagctcg
     2461 attatcggat ccagaatgcc gcgcaccgtc gggcttagcc ccatggcgat cccgaccgga
     2521 ataccgatca acaccgccgc gagtagcgcc agcaaaatgc gcgtcaggct ggctgccaga
     2581 tgctgccaca gcgtggcgtc cataaatccc tgcggtccgg caatggtgag cagttttgcc
     2641 aggacctgtt gcggtggcgg caaaaacagc gggctaatca gttgcagcgc cgccaccgcc
     2701 caccatacag tgagtaaaac cgctaacgtg ccaatgctta aggtcacctg acgcgagagc
     2761 ggccagcgcc atttcagccg atgcgaatgc agtttttcat taatgagcac actcatgaga
     2821 atgcctcccg ttgctcaaat acgcggctta aaacatattc gcgcatggcg atgaattgtg
     2881 gatcggactt gatgctgcgg ctcggttccc cggcaacaaa gcggcgagca aagttgagcg
     2941 gcagccgctc cagcacgcgg ccagggccgg atgaaagcag aaccagttca gtcgccataa
     3001 acaccgcttc ttctatatcg tgggtaatca acagcacctg cttgcccgtc tcctgccaga
     3061 gtttcagcag cagggtttgc atctgatcgc gggtgaaggc gtccagcgcg ccaaacggtt
     3121 cgtcgagtaa taacagctgg ggattcgccg ccagcgcgcg ggcaatccct acccgctgac
     3181 gttgaccgcc ggaaagctgc cagatatagc gtttttccgc ccc
//
LOCUS       DADXDL010000212         3198 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.213, whole genome shotgun sequence.
ACCESSION   DADXDL010000212 DADXDL010000000
VERSION     DADXDL010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3198
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.213"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..603)
                     /gene="dsbA"
                     /locus_tag="IRB70_004863"
     CDS             complement(<1..603)
                     /gene="dsbA"
                     /locus_tag="IRB70_004863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiol:disulfide interchange protein DsbA"
                     /protein_id="HBC0634660.1"
                     /translation="MKKIWLALAGLVLAFSASAAQYEDGKQYTTLEKPVAGAPQVLEF
                     FSFFCPHCYQFEEVLHISDNVKKKLPEGVKMTKYHVNFMGGDLGKDLTQAWAVAMALG
                     VEDKVTVPLFEGVQKTQTIRSASDIRDVFINAGIKGEEYDAAWNSFVVKSLVAQQEKA
                     AADVQLRGVPAMFVNGKYQLNPQGMDTSNMDVFVQQYADTV"
     gene            complement(620..1606)
                     /gene="srkA"
                     /locus_tag="IRB70_004864"
     CDS             complement(620..1606)
                     /gene="srkA"
                     /locus_tag="IRB70_004864"
                     /EC_number="2.7.11.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stress response kinase SrkA"
                     /protein_id="HBC0634661.1"
                     /translation="MNNSAFTFQTLHPDTIMDALFEQGIRVDSGLTPLNSYENRVYQF
                     QDEDRRRFVVKFYRPERWTADQILEEHQFALQLVNDEVPVAAPVAFNGQTLLNHQGFY
                     FAVFPGVGGRQFEADNIDQMEAVGRYLGRMHQTGRKQLFIHRPTIGLNEYLIEPRKLF
                     EDATLIPSGLKAAFLKATDELIAAVTAHWREDFTVLRLHGDCHAGNILWRDGPMFVDL
                     DDARNGPAIQDLWMLLNGDKAEQRMQLETIIEAYEEFSEFDTAEIGLIEPLRAMRLVY
                     YLAWLMRRWADPAFPKNFPWLTGEDYWLRQTATFIEQAKVLQEPPLQLTPMY"
     gene            complement(1683..1952)
                     /locus_tag="IRB70_004865"
     CDS             complement(1683..1952)
                     /locus_tag="IRB70_004865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015966571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihD family protein"
                     /protein_id="HBC0634662.1"
                     /translation="MKCKRLNEVIELLQPAWQKEPDLNLLQFLQKLAKESGFDGELAD
                     LTDDILIYHLKMRDSAKDAVIPGLQKDYEEDFKTALLRARGVIKE"
     gene            2022..2606
                     /gene="mobA"
                     /locus_tag="IRB70_004866"
     CDS             2022..2606
                     /gene="mobA"
                     /locus_tag="IRB70_004866"
                     /EC_number="2.7.7.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdenum cofactor guanylyltransferase MobA"
                     /protein_id="HBC0634663.1"
                     /translation="MNLMTTITGVVLAGGKARRMGGVDKGLLELNGKPLWQHVADALM
                     TQLSHVVVNANRHQEIYQASGLKVIEDSLADYPGPLAGMLSVMQQEAGEWFLFCPCDT
                     PYIPQDLAARLNHQRKDAPVVWVHDGERDHPTIALVNRAIEPLLQEYLQAGERRVMAF
                     MRQAGGHAVDFSDHKDAFVNVNTPEELARWQERQ"
     gene            2588..3115
                     /gene="mobB"
                     /locus_tag="IRB70_004867"
     CDS             2588..3115
                     /gene="mobB"
                     /locus_tag="IRB70_004867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molybdopterin-guanine dinucleotide biosynthesis
                     protein B"
                     /protein_id="HBC0634664.1"
                     /translation="MAGKTMIPLLAFAAWSGTGKTTLLKKLIPALCARGIRPGLIKHT
                     HHDMDVDKPGKDSYELRKAGAAQTIVASQQRWALMTETPDEEELDLHFLASRMDASKL
                     DLILVEGFKHEEIAKIVLFRDGTGHRPEELVIDRHVIVVASDVPLNLDVALLDINDVE
                     GLADFVVEWMQKQDG"
BASE COUNT          845 a          785 c          771 g          797 t
ORIGIN      
        1 cacagtatca gcatactgct gaacaaaaac atccatattg ctggtatcca taccctgcgg
       61 attcagctga tatttaccgt taacaaacat cgccggaacg ccacgcaatt gcacgtcagc
      121 tgcagctttt tcctgctgag cgaccaggga tttcaccacg aagctgttcc acgccgcgtc
      181 gtactcttca cctttaatac ctgcgttgat aaatacatcg cggatatcag atgctgaacg
      241 aatggtctgg gttttctgta cgccttcaaa cagcggaaca gtgactttgt cttccacgcc
      301 cagtgccatc gccactgccc atgcctgagt cagatctttg cccaggtcac cacccatgaa
      361 gttgacgtgg tatttagtca tcttcacgcc ttccggcagt tttttcttca cgttatcaga
      421 aatatgcaga acttcttcaa actgatagca gtgcgggcag aagaaagaga aaaactccag
      481 cacttgcggc gcgccagcaa ctggtttttc cagggtagtg tactgtttac catcttcata
      541 ctgcgccgcc gatgcgctaa acgctaaaac taaaccagcc agcgccagcc aaatcttttt
      601 catgatctac tctctccgat taatacatag gtgttaattg caaagggggt tcttgtagaa
      661 cttttgcctg ttctataaaa gtcgccgtct gtcgtagcca gtaatcttcc ccggttaacc
      721 acgggaaatt tttcgggaac gcgggatcag cccaacgccg cattagccag gcaagataat
      781 aaaccaaacg catggcgcgt aaaggttcaa tcagtccgat ttcagcagtg tcgaactcgc
      841 taaattcttc ataagcttca ataatagttt ccagttgcat ccgctgctcg gctttatcgc
      901 cattgagcaa catccacaaa tcctgaatag ccggaccatt acgtgcatca tccagatcaa
      961 caaacattgg accatcgcgc cagagaatat tcccagcgtg gcagtctcca tgtagccgca
     1021 gaacggtgaa atcttcccgc cagtgtgctg taacggcggc gatcagctca tctgtcgctt
     1081 tcagaaatgc cgctttcaac ccggaaggta tcagtgtagc gtcctcaaac agcttgcgag
     1141 gctcaatgag atattcattc agaccgatgg tcgggcgatg gataaaaagc tgtttgcgcc
     1201 ccgtctggtg catacgccct aaataacgcc caaccgcttc catctgatcg atattatcag
     1261 cttcgaactg gcgaccaccg acgcctggaa aaacagcgaa ataaaatccc tgatgattca
     1321 ataaagtctg accgttaaag gccacaggtg ctgcgaccgg aacttcatca tttaccaact
     1381 gcaacgcaaa ttgatgttct tcgaggattt gatcggctgt ccaacgttca ggacgataaa
     1441 atttgacgac aaaacgtcga cgatcttcgt cctgaaattg atagacacgg ttttcatagc
     1501 tgttaagcgg ggtaagaccg gaatccaccc ggatcccttg ctcaaacaga gcatccatga
     1561 tggtatccgg gtgtagtgtc tggaaagtaa aagcgctgtt gttcatccca tcatccggaa
     1621 aacattacga atgatgaagg atatcatttc atgatgattt tggtggcacc gcttacaagc
     1681 ttttactctt taattacgcc acgtgcgcgt aatagcgccg ttttgaaatc ttcttcataa
     1741 tctttctgca aacccggaat caccgcatct ttcgcggaat cacgcatttt caggtgatag
     1801 atcagaatgt catccgtcaa atccgccagt tcgccgtcaa aacctgactc tttcgccagt
     1861 ttctgcaaaa attgcagcag gttaaggtct ggctcttttt gccaggctgg ctggaggagt
     1921 tcaataactt cattcagacg tttacatttc atagtaatgc tccttactct tgagacagac
     1981 acgttagcag ggtcaatccc acaataaaag aggcgatatc ggtgaatctg atgacgacga
     2041 taacaggcgt tgtgctggca ggcggtaaag ccagacgaat gggcggcgta gataaaggat
     2101 tgcttgaatt aaacggcaaa ccattatggc aacatgtcgc tgacgcgctt atgacgcagc
     2161 tctctcacgt cgtggttaat gctaatcgtc atcaggaaat ctatcaggca agcggtctga
     2221 aagtgattga agattcactg gcggattacc caggccctct ggcaggaatg ctttcagtaa
     2281 tgcagcagga agcgggtgag tggtttttgt tttgtccgtg cgatacgcct tatattcccc
     2341 aggatttagc cgcccggctt aatcatcagc gcaaagatgc gcctgtcgtg tgggtccacg
     2401 acggtgaacg cgatcacccg actattgctc tggtaaaccg cgctattgag cctttattac
     2461 aagaatattt gcaagcagga gaacgccggg taatggcatt tatgcgtcag gctggcggtc
     2521 atgcggttga tttcagcgat cataaagatg catttgttaa cgtgaatacg ccagaggagc
     2581 ttgcccgatg gcaggaaaga caatgatacc gttactcgcc tttgccgcgt ggagtggcac
     2641 cggaaaaacg acgctgctga aaaaactgat cccggcatta tgcgccagag ggatccgtcc
     2701 ggggctgatt aagcatacgc accatgatat ggatgttgat aaaccgggca aagatagcta
     2761 tgagctgcgc aaggctggcg cggcgcaaac catcgttgcc agccagcaac gatgggcttt
     2821 gatgacagaa acgccagacg aagaagaact ggatctgcat tttctcgcaa gccggatgga
     2881 tgcttcaaag ctggatttga ttctggtcga agggtttaag catgaagaga tcgcaaagat
     2941 tgtgctgttt cgcgatggaa ccggacatcg accagaagaa ttagtgatag acagacatgt
     3001 tattgttgta gccagtgatg tgccgcttaa tcttgatgtc gcgttactgg atattaatga
     3061 tgttgagggg ctggctgatt ttgtggtgga gtggatgcaa aagcaggacg gataagcaag
     3121 agtaggctgg agcaaacgcg ccagcgtcgc atccggcatt tattccgcac caacgcaaaa
     3181 aagcccagtc ttccgact
//
LOCUS       DADXDL010000213         3140 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.214, whole genome shotgun sequence.
ACCESSION   DADXDL010000213 DADXDL010000000
VERSION     DADXDL010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3140)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3140)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3140
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.214"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(1..430)
                     /locus_tag="IRB70_004868"
                     /pseudo
     CDS             complement(1..430)
                     /locus_tag="IRB70_004868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311759.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="YopN family type III secretion system gatekeeper
                     subunit"
     gene            complement(435..2138)
                     /locus_tag="IRB70_004869"
     CDS             complement(435..2138)
                     /locus_tag="IRB70_004869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscC/YscC/HrcC family type III secretion system
                     outer membrane ring protein"
                     /protein_id="HBC0634665.1"
                     /translation="MKIKLRITIILISALCIFNGLLTPGAYAATANGYVANKENLRSF
                     FETVSSYAGKPTIVSKLAMKKQISGNFDLTEPYALIERLSAQMGLIWYDDGKAIYIYD
                     SSEMRNALINLRKVSTNEFNHFLKKSGLYNSRYEIKGGGNGTFYVSGPPVYVDLVVNA
                     AKLMEQNSDGIEIGRNKVGIIHLVNTFVNDRTYELRGEKIVIPGMAKVLSTLLNNNIK
                     QSTGVNVLSEISSRQQLKNVSRMPPFPGAEEDDDLQVEKIISTAGAPETDDIQIIAYP
                     DTNSLLVKGTVSQVDFIEKLVATLDIPKRHIELSLWIIDIDKTDLEQLGADWSGTIKI
                     GSSLSASFNNSGSISTLDGTQFIATIQALAQKRRAAVVARPVVLTQENIPAIFDNNRT
                     FYTKLVGERTAELDEVTYGTMISVLPRFAARNQIELLLNIEDGNEINSDKTNVDDLPQ
                     VGRTLISTIARVPQGKSLLIGGYTRDTNTYESRKIPILGSIPFIGKLFGYEGTNANNI
                     VRVFLIEPREIDERMMNNANEAAVDARAITQQMVKNKEINDELLQKWIKTYLNREVVG
                     G"
     gene            complement(2135..2884)
                     /locus_tag="IRB70_004870"
     CDS             complement(2135..2884)
                     /locus_tag="IRB70_004870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0634666.1"
                     /translation="MIEEGLLLPMNVLLQGQRLTLLDPEMWFLRGNENKDVTLVITIG
                     NNHQKLMVVEDILLLIDRSQIEVTAGKVIYHPLRIDILSKLLAFIDESTGSVEREHHE
                     LFADALPFASEVVLFSKVASEAWFLATYLSSDNINEILFQHLRKTECYKLVRYLLSQS
                     LIQTSLYDLGELYGVSYSHFRRLCSYALGGKVKTELCGWRVARAVLEIIEGNSDMTTI
                     AHKYGYSSSSHFSAEVKSRLGKTPRELCKKL"
BASE COUNT          893 a          681 c          516 g         1050 t
ORIGIN      
        1 gcgtttagcc gcacattttc agatatttgt ttttacgtaa aattgcacgt aatacaacca
       61 ccagatcgct ttcatctgga aataattttt tagcaaagct atacacttca tagtcatggg
      121 tagttgctgc cttaagcgcc tccatgactt tatcggtttt ttctattggc tgatcttcca
      181 ggacatattc ttctccgtcc agaaagttgg ccagttgttc ttcgtagatt tttttcttca
      241 taaactgcgt taacgctgct gacatctcgt cagtagcttg taagaatcga gcttctttac
      301 cggcgggatc atcccccatt ttaggcattt cagcttcaat atcttcatta tcttctgtga
      361 taatgtcctc taagcgagaa acttctctgg ctctttctaa tacaccgaca tgttctacat
      421 gaatcgccat ttcactatcc tccgacgact tcacgattca ggtaagtttt tatccatttc
      481 tgcagtaatt catcgttgat ttctttattt tttaccattt gctgtgttat tgctctggcg
      541 tcaaccgcag cctcattcgc attattcatc atgcgctcat cgatctctct tggctcaata
      601 agaaagacac gaacgatgtt attcgcattt gttccttcat atccaaataa tttaccaata
      661 aatggaatac tgcctaatat tgggatcttg cgactttcat aggtattcgt atctcgtgta
      721 tatccaccaa tcaaaagact tttcccttga ggcacgcgcg caatagtact tataagcgtt
      781 ctaccaacct gaggcagatc atcaacattg gtcttgtcag aattgatttc attgccatct
      841 tcaatattca agagtaattc aatttgattt cgcgcagcaa atcgtggtag cacgctaatc
      901 atcgtaccat aggttacttc atccaattcc gcagtacgct cgccgactaa tttagtatag
      961 aaagtacggt tattatcaaa tatagcagga atattctcct gtgttaaaac gacaggacga
     1021 gcaacaacgg cggctcttct tttttgcgca agtgcctgta ttgttgcaat aaactgtgtc
     1081 ccatccaggg tactaattga acctgaatta ttaaatgatg cacttaggct ggatccaatt
     1141 tttatcgtgc ccgaccagtc agctcctaac tgttctagat cagtcttatc aatatctatt
     1201 atccataaag ataattcaat atgtcgcttt ggaatatcga gcgtagctac taacttctcg
     1261 ataaaatcaa cctgagatac tgttccttta acaagtaaac tgttggtatc aggatatgca
     1321 ataatttgta tatcgtcagt ctctggcgct ccagctgtcg atattatttt ctctacttgt
     1381 aggtcatcat cttcttcagc accaggaaaa ggaggcatac gtgatacgtt ttttagttgt
     1441 tgacgacttg aaatttcaga aagtacgtta accccagtgc tttgcttaat gttattattt
     1501 aacaatgtcg atagtacttt tgccatgcca ggaataacta tcttttcgcc acgtaattca
     1561 taagtccgat cattaacgaa tgtgttgacc agatgaatta ttcctacttt atttcgtccg
     1621 atctcgatgc catcgctgtt ttgctccatc aattttgcag cattaacgac caggtcaaca
     1681 tacaccggtg gccctgaaac atagaaagta ccattgcctc cccctttaat ttcataacga
     1741 gagttataca gacctgattt ttttaaaaaa tgattaaact cattcgtcga tacctttctc
     1801 agattaatca gtgcattacg catctctgat gagtcataga tataaatagc tttgccatca
     1861 tcataccaaa taagccccat ctgcgccgac aggcgttcaa tcaaggcata gggttcggtt
     1921 aaatcaaaat ttccgctgat ctgtttcttc atggcaagct tactaactat tgtaggctta
     1981 cccgcatatg atgaaaccgt ttcaaaaaaa ctacgtagat tttctttatt tgctacgtat
     2041 ccattcgctg ttgcggcata tgcaccagga gtcaataatc cattaaaaat gcataaggct
     2101 gaaattaata taatagtaat acgtaatttt attttcataa ctttttacat agttctctcg
     2161 gtgtttttcc taaccggctt tttacttcgg ctgaaaagtg tgatgaggat gagtagccat
     2221 atttatgcgc aatagttgtc atatcactgt ttccttcaat gatttccaac acggctctgg
     2281 caactctcca gccacataat tccgttttaa ctttaccacc caatgcataa ctacataaac
     2341 ggcgaaaatg tgaatacgat acgccgtaaa gctcaccaag atcatagagt gaagtctgta
     2401 tgagcgattg cgataataaa tagcgaacca gtttatagca ttctgttttt cttagatgct
     2461 gaaacagaat ttcattaata ttatcgctgc tcagataagt ggctaaaaac caggcttcac
     2521 ttgcaacttt actgaatagc acaacttctg atgcaaaggg caaggcatca gcaaacaact
     2581 catggtgttc cctttccaca ctccccgttg attcatcaat aaaagctaat aatttactca
     2641 ggatatcaat gcgaagtgga tgataaatta ctttccctgc agttacctca atttggcttc
     2701 ggtcaatgag cagtaatatg tcttccacta ccattaattt ttgatggtta ttaccaatcg
     2761 taataacaag ggttacatcc ttgttttcat ttccccgtaa gaaccacatt tcagggtcga
     2821 gtagggttaa cctctgtcct tgaagcaaaa cattcattgg aagtaacagc ccttcttcaa
     2881 tcatgtttca tctccttatt ccatattctc attctccata aacttgcaat aaaaacatga
     2941 ttaaaaagtg atgattccta tttataaaat aatgattttg ttatgagcga atagctatca
     3001 gctacttaca gtagtaagtc atcctgtcca tatacagaat tgcaactgtt gatatgtttt
     3061 acttaaacat accccgtatt tcttataaca cttgtttggt gactattttc aataaaaatc
     3121 atatttgtta gttacacatt
//
LOCUS       DADXDL010000214         3117 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.215, whole genome shotgun sequence.
ACCESSION   DADXDL010000214 DADXDL010000000
VERSION     DADXDL010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3117)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3117)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3117
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.215"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            148..1464
                     /gene="shiA"
                     /locus_tag="IRB70_004871"
     CDS             148..1464
                     /gene="shiA"
                     /locus_tag="IRB70_004871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate transporter"
                     /protein_id="HBC0634667.1"
                     /translation="MDSTLISTRPDEGTLSLSRARRAALGSFAGAVVDWYDFLLYGIT
                     AALVFNREFFPQVSPAMGTLAAFATFGVGFLFRPLGGVIFGHFGDRLGRKRMLMLTVW
                     MMGIATALIGILPSFSTIGWWAPILLVTLRAIQGFAVGGEWGGAALLSVESAPKNKKA
                     FYSSGVQVGYGVGLLLSTGLVSLISMMTTDEQFLSWGWRIPFLFSIVLVLGALWVRNG
                     MEESAEFEQQQHYQAAAKKRIPVIEALLRHPGAFLKIIALRLCELLTMYIVTAFALNY
                     STQNMGLPRELFLNIGLLVGGLSCLTIPCFAWLADRFGRRRVYITGTLIGTLSAFPFF
                     MALEAQSIFWIVFFSIMLANIAHDMVVCVQQPMFTEMFGASYRYSGAGVGYQVASVVG
                     GGFTPFIAAALITYFAGNWHSVAIYLLAGCLISAMTALLMKDSQRA"
     gene            1566..3020
                     /gene="amn"
                     /locus_tag="IRB70_004872"
     CDS             1566..3020
                     /gene="amn"
                     /locus_tag="IRB70_004872"
                     /EC_number="3.2.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AMP nucleosidase"
                     /protein_id="HBC0634668.1"
                     /translation="MNNKGSGLTPAQALDKLDALYEQSVVALRNAIGNYITSGELPDE
                     NARKQGLFVYPSLTVTWDGSTTNPPKTRAFGRFTHAGSYTTTITRPTLFRSYLNEQLT
                     LLYQDYGAHISVQPSQHEIPYPYVIDGSELTLDRSMSAGLTRYFPTTELAQIGDETAD
                     GIYHPTEFSPLSHFDARRVDFSLARLRHYTGTPVEHFQPFVLFTNYTRYVDEFVRWGC
                     SQILDPDSPYIALSCAGGNWITAETEAPEEAISDLAWKKHQMPAWHLITADGQGITLV
                     NIGVGPSNAKTICDHLAVLRPDVWLMIGHCGGLRESQAIGDYVLAHAYLRDDHVLDAV
                     LPPDIPIPSIAEVQRALYDATKLVSGRPGEEVKQRLRTGTVVTTDDRNWELRYSASAL
                     RFNLSRAVAIDMESATIAAQGYRFRVPYGTLLCVSDKPLHGEIKLPGQANRFYEGAIS
                     EHLQIGIRAIDLLRAEGDRLHSRKLRTFNEPPFR"
BASE COUNT          721 a          771 c          771 g          854 t
ORIGIN      
        1 ccgtcagtag ctgaacagga gggacagctg atagaaacag aagccactga agcacctcaa
       61 aaacaccatc atacactaaa tcagtaagtt ggcagcatca ccccttttcc atactaatta
      121 taaaaagaca gtacaaacag gatcattatg gactccacgc tcatctccac tcgtcccgat
      181 gaagggacgc tttcgttaag tcgcgcccga cgagctgcgt taggcagctt cgctggtgcc
      241 gtcgtcgact ggtatgattt tttactctat ggcatcaccg ccgcactggt gtttaatcgc
      301 gagtttttcc cgcaagtaag cccggcgatg ggaacgctcg ccgcatttgc tacctttggc
      361 gtcggatttc ttttccgtcc gctcggcggt gtcattttcg gtcactttgg cgaccgactg
      421 ggacgtaagc gcatgttaat gctgaccgtc tggatgatgg gcatcgcgac agccttgatt
      481 ggtattcttc cttcattctc gaccattggg tggtgggcac ctattttgct ggtgacactg
      541 cgtgccattc agggatttgc agtcggcggc gaatggggag gcgcggcgtt gctttccgtt
      601 gaaagtgcac cgaaaaataa aaaagccttt tacagtagcg gtgtacaagt tggctacggt
      661 gtaggtttac tgctttcaac cggactggtt tcattgatca gtatgatgac gactgacgaa
      721 cagtttttaa gctggggctg gcgcattcct ttcctgttta gcatcgtact ggtactggga
      781 gcattgtggg tgcgcaatgg catggaggag tccgcggaat ttgaacaaca gcaacattat
      841 caagctgccg cgaaaaaacg catcccggtt atcgaagcgc tgttacgaca tcccggtgct
      901 ttcctgaaga ttattgcgct acgactgtgc gaattgctga cgatgtacat cgttactgcc
      961 tttgcactta attattcaac ccagaatatg gggctaccgc gcgaactttt ccttaatatt
     1021 ggtttgctgg taggtggatt aagctgcctg acaattccct gttttgcctg gcttgccgat
     1081 cgttttggtc gccgtagggt ttatatcaca ggtacgttaa tcggaacgtt gagcgcattt
     1141 cctttcttta tggcgcttga agcacaatct attttctgga tagttttctt ctccataatg
     1201 ctggcaaaca ttgcgcatga catggtggtg tgtgtgcaac aaccgatgtt taccgaaatg
     1261 tttggtgcca gttatcgcta tagtggcgct ggagtcggtt atcaggttgc cagtgtggtt
     1321 ggcggtggat ttacaccttt tattgccgct gcactcatca cttactttgc cgggaactgg
     1381 catagcgtcg ccatttattt gctggctgga tgcctgattt ccgcaatgac cgctttgttg
     1441 atgaaagaca gtcaacgcgc ttgatagcct ggcgaagatc atccgatctt cgccttacac
     1501 ttttgtttca catttctgtg acatactatc ggatgtgcgg taattgtatg gaacaggaga
     1561 cacacatgaa taataagggc tccggtctga ccccagctca ggcactggat aaactcgacg
     1621 cgctgtatga gcaatctgta gtcgcattac gcaacgccat tggcaactat attacaagtg
     1681 gcgaattacc tgatgaaaac gcccgcaaac aaggtctttt tgtctatcca tcactgaccg
     1741 taacctggga cggtagcaca accaatcccc ccaaaacgcg cgcatttggt cgctttaccc
     1801 acgcaggcag ctacaccacc acgattactc gccctactct ctttcgttcg tatcttaatg
     1861 aacaacttac gttgctgtat caggattatg gtgcgcatat ctcagtgcaa ccctcgcagc
     1921 atgaaatccc ttatccttat gtcatcgatg gctctgaatt gacacttgat cgctcaatga
     1981 gcgctgggtt aactcgctac ttcccgacaa cagaactggc gcaaattggc gatgaaactg
     2041 cagacggcat ttatcatcca actgaattct ccccgctatc gcattttgat gcgcgccgcg
     2101 tcgatttttc cctcgcacgg ttgcgccatt ataccggtac gccagttgaa cattttcagc
     2161 cgttcgtctt gtttaccaac tacacacgtt atgtggatga attcgttcgt tggggatgca
     2221 gccagatcct cgatcctgat agtccctaca ttgccctttc ttgtgctggc gggaactgga
     2281 tcaccgccga aaccgaagcg ccagaagaag ccatttccga ccttgcatgg aaaaaacatc
     2341 agatgccagc atggcattta attaccgccg atggtcaggg tattactctg gtgaatattg
     2401 gcgtgggacc gtcaaatgct aaaaccatct gcgatcatct ggcagtgcta cgcccggatg
     2461 tctggttgat gattggtcac tgtggcggat tacgtgaaag tcaggccatt ggcgattatg
     2521 tacttgcaca cgcttattta cgcgatgacc acgttcttga tgcggttctg ccgcccgata
     2581 ttcctattcc gagcattgct gaagtgcaac gtgcgcttta tgacgccacc aagctggtga
     2641 gcggcaggcc cggtgaggaa gtcaaacagc ggctacgtac tggtactgtg gtaaccacag
     2701 atgacaggaa ctgggaatta cgttactcag cttctgcact tcgttttaac ttaagccggg
     2761 ccgtagcaat tgatatggaa agtgcaacca ttgccgcgca aggatatcgt ttccgcgtgc
     2821 catacgggac actactgtgt gtttcagata aaccgttgca tggcgagatt aaacttcccg
     2881 gccaggctaa ccgtttttat gaaggcgcta tttccgaaca tctgcaaatt ggcattcggg
     2941 cgatcgattt gctgcgcgca gaaggcgacc gactgcattc gcgtaaatta cgaaccttta
     3001 atgagccgcc gttccgataa taagttctga accttcttat cagaaataga tgtgaaggag
     3061 taagtaagac acctggcaaa tagcctgcaa taatcgtggg ctgtttgctt ccttggg
//
LOCUS       DADXDL010000215         3072 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.216, whole genome shotgun sequence.
ACCESSION   DADXDL010000215 DADXDL010000000
VERSION     DADXDL010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3072)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3072)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3072
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.216"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            285..713
                     /gene="tolA"
                     /locus_tag="IRB70_004873"
     CDS             285..713
                     /gene="tolA"
                     /locus_tag="IRB70_004873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001479285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell envelope integrity protein TolA"
                     /protein_id="HBC0634669.1"
                     /translation="MGFRSASILTLIISGIIIGCTDAVSTNYHDRTSYYSDKAIETQY
                     VSSSERTSDVSEDIRLYAHQIKSAIEKQFGDASKYSGKECTLRMHMAPNGLLLEVKRE
                     SGDLDLCREAMNAIKNVDIPAPPSPEVYKVFQNGVLDFKP"
     gene            885..1259
                     /locus_tag="IRB70_004874"
     CDS             885..1259
                     /locus_tag="IRB70_004874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tolA family protein"
                     /protein_id="HBC0634670.1"
                     /translation="MLTFWVGFVAGCTPLHPSDCHKTTATGSCSSGRWDDQDEWGAQA
                     RGIRAAINAKLDEPHNWKGKKCRLHMEFSQDGTALKISTSNGDKAYCEAIKSAAHKAK
                     FPAFNNPEVYRDFQKSGFDMRG"
     gene            1511..1726
                     /gene="essD"
                     /locus_tag="IRB70_004875"
     CDS             1511..1726
                     /gene="essD"
                     /locus_tag="IRB70_004875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_415086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage lysis protein EssD"
                     /protein_id="HBC0634671.1"
                     /translation="MKSMDKISTGIAYGTSAGSAGYWFLQLLDKVTPSQWAAIGVLGS
                     LVFGLLTYLTNLYFKIKEDRRKAARGE"
     gene            1731..2042
                     /locus_tag="IRB70_004876"
     CDS             1731..2042
                     /locus_tag="IRB70_004876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1327 domain-containing protein"
                     /protein_id="HBC0634672.1"
                     /translation="MTQYYELVVKGVRNFENKVTVTVALQDKERFDGEIFGLDVAMDR
                     VEGAALEFYEAAARMSVRQVFLEVAEKLSEKVESYLQHQYSFKIENPANKHERPHHKY
                     L"
     gene            2039..2572
                     /locus_tag="IRB70_004877"
     CDS             2039..2572
                     /locus_tag="IRB70_004877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme"
                     /protein_id="HBC0634673.1"
                     /translation="MNTKIRYGLSAAVLALIGAGASAPQILDQFLDEKEGNHTMAYRD
                     GSGIWTICRGATVVDGKNVFPNMKLSKEKCDQVNAIERDKALAWVERNIKVPLTEPQK
                     AGIASFCPYNIGPGKCFPSTFYKRLNAGDRKGACEAIRWWIKDGGRDCRIRSNNCYGQ
                     VIRRDQESALTCWGIEQ"
     gene            2569..3066
                     /locus_tag="IRB70_004878"
     CDS             2569..3066
                     /locus_tag="IRB70_004878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2514 domain-containing protein"
                     /protein_id="HBC0634674.1"
                     /translation="MNQIFTVILLVLVGFVVGNVWSDRGWQKKWAERDAAELSQEVNV
                     QFAARIIEQGRSISRDEAVKDAQQKAAEISARAADLSDSVNQLRAEATKYAIRLDAAQ
                     HTANLAAAVRGKTTKAAEGMLTNMLGDIAAEAQLYAEIADKRYIAGVTCQRIYESLRD
                     KKYQM"
BASE COUNT          891 a          611 c          768 g          802 t
ORIGIN      
        1 taaaagaaac tggcatggtg aatccccctg tgcggagggg caatcagcga gtaggtatat
       61 gggataatcg cggattcagg tgctggtact gaattcaccg ggaggcaccc ggcaccatgc
      121 acttcaatag attctctcca cattatggat attctttcag aatatcccac gcagactttg
      181 tgtaaatgtt aacaaatgtg cgttttattt gatctgattc gctgtttgag cgtccaaaac
      241 aacggtatat ataatccttt actatatgac atatgtgagg aaaaatgggt tttcgtagcg
      301 catcaattct tacgttgatt attagtggga ttattatcgg gtgcactgat gctgtatcga
      361 caaattatca tgaccgtaca tcatattact ccgataaagc aatagagaca cagtatgtga
      421 gttcatctga acgtacttct gatgttagtg aggatatccg tctgtatgcc catcaaatca
      481 agagcgccat cgaaaaacag ttcggggatg cgagtaagta ttcaggaaaa gagtgtacac
      541 tgagaatgca tatggccccg aatggccttc tactggaggt taaaagagaa agtggagacc
      601 tcgatttatg tcgtgaagcg atgaatgcga taaagaatgt tgatatacct gccccccctt
      661 cgccggaagt atataaagta tttcaaaatg gggtgctgga ttttaaaccc tgatatttat
      721 tgttttgtaa taaacggttt cggcttaggt ttgttctgac acaactacgg cactgagcta
      781 aatttagcgg atagtcagct ctgagccagt ggcggacgta acaactacta ttgctgagat
      841 tttaatggat tgaggagcaa gaagtgggat taaagaaaat cgttatgttg actttttggg
      901 tcggttttgt tgcgggatgc acacctttac acccttcaga ttgccacaaa actactgcta
      961 caggtagttg cagttcagga cgctgggatg atcaggatga atggggggcg caagcgcggg
     1021 gaatcagagc tgcaattaat gccaaacttg atgagccgca taactggaaa gggaaaaaat
     1081 gcaggttgca tatggaattc tctcaggatg gcacggcgtt aaaaatatct accagtaacg
     1141 gtgataaagc ctattgcgaa gcgataaagt ccgcagctca taaagccaaa tttccggcct
     1201 tcaacaatcc ggaagtctac agagattttc agaaatctgg ctttgacatg cgaggttagc
     1261 tcttcaatta ctatatctca ttcatagcaa actgacagat ttgatgatgt tctatatacg
     1321 aaacctgtga tgtcaagtct gagctaatac aaataaacat aatatcagag aaatacattt
     1381 tattagctcg ctacggcgag ctttttatat tgcatcgtct ccagcatata tatcaattaa
     1441 ggctctgatt gatgtgtctg gaagcctaca cataataact atgccatccg ttccgtgcgg
     1501 aggtgaggct atgaaatcca tggacaaaat ttcaacaggc attgcctacg gcacctccgc
     1561 aggcagtgct ggctactggt ttttacagct gctcgataaa gtcacgccct cacagtgggc
     1621 agcaataggt gtgctgggta gcctggtatt tggcctgctg acgtacctga caaatcttta
     1681 tttcaagatt aaagaagaca ggcgtaaggc tgcgagagga gagtaatcca atgactcaat
     1741 actatgaact ggttgtgaaa ggagtccgta attttgagaa taaagttacg gtaactgtag
     1801 ccttacagga caaagaacgc tttgacggtg aaatttttgg cctggatgtc gccatggacc
     1861 gtgttgaagg agctgcgctg gagttttatg aggcagcagc cagaatgagc gtccggcaag
     1921 tcttcctgga agtagcagaa aaattgtcag aaaaagttga gtcttatctg cagcatcagt
     1981 actcctttaa gattgaaaat cctgccaata agcacgagcg tcctcatcat aaatatctat
     2041 gaacacaaaa atcagatacg gcctgtcggc tgccgttctg gcgctgattg gtgctggcgc
     2101 atctgctcct cagatacttg accagtttct ggacgaaaaa gaaggtaacc acacaatggc
     2161 ataccgcgat ggttctggca tatggaccat ctgtcggggt gccacagtgg tggatggaaa
     2221 aaacgttttt cccaatatga aactgtcgaa ggaaaaatgc gaccaggtca acgccattga
     2281 gcgtgataag gcgctggcat gggtggagcg caatataaaa gttccactga ccgagccaca
     2341 gaaagccggt atcgcgtcat tctgtcccta taacattggc cctggtaagt gttttccgtc
     2401 gacgttttat aagcggctta atgccggtga tcgtaaaggc gcatgcgagg cgattcgctg
     2461 gtggataaag gacggtggac gtgattgccg cattcgttca aataattgtt acggtcaggt
     2521 tattcgtcgt gaccaggaga gtgcattaac ctgctggggg atagaacagt gaatcagata
     2581 ttcacggtga ttttgctcgt gttggtagga tttgtcgtag gtaatgtctg gagcgacaga
     2641 ggatggcaaa aaaaatgggc ggagcgtgat gctgccgaat tatctcaaga ggtaaatgtc
     2701 caatttgctg ctcgaataat tgaacagggg cgaagtatat cccgtgatga ggctgttaaa
     2761 gatgcacaac agaaagccgc tgaaatttct gccagggctg ctgatctgtc tgatagtgtt
     2821 aaccagctgc gtgccgaagc aacaaaatat gccatacgcc ttgacgcagc gcagcatacc
     2881 gcaaatcttg ccgctgccgt cagaggcaaa acaaccaaag ccgccgaagg aatgctcacc
     2941 aacatgctcg gagatattgc agcagaagct cagctttatg ctgaaattgc tgacaaacgc
     3001 tacatcgcag gagtgacttg tcaacggatt tatgaatctt taagagataa aaaatatcag
     3061 atgtagatta at
//
LOCUS       DADXDL010000216         2987 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.217, whole genome shotgun sequence.
ACCESSION   DADXDL010000216 DADXDL010000000
VERSION     DADXDL010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2987)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2987)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2987
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.217"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            296..1021
                     /locus_tag="IRB70_004879"
     CDS             296..1021
                     /locus_tag="IRB70_004879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBC0634675.1"
                     /translation="MLPGCCKNGIVISKIPVMQAGLKEVMRTHFPEYEIISSASAEDL
                     TLLQLRRSGLVIADLAGESEDPRSVCEHYYSLISQYREIHWVFMVSRSWYSQAVELLM
                     CPTATLLSDVEPIENLVKTVRSGNTHAERISAMLTSPAMTETHDFSYRSVILTLSERK
                     VLRLLGKGWGINQIASLLKKSNKTISAQKNSAMRRLAIHSNAEMYAWINSAQGARELN
                     LPSVYGDAAEWNTAELRREMSHS"
     gene            979..1656
                     /gene="bglJ"
                     /locus_tag="IRB70_004880"
     CDS             979..1656
                     /gene="bglJ"
                     /locus_tag="IRB70_004880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418786.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional activator BglJ"
                     /protein_id="HBC0634676.1"
                     /translation="MEHSRIKKRNVALIEKCVMSSIGIESLFRKFAGNPYKLHTYTSQ
                     ESFQDAMSRISFAAVIFSFSAMRSERREGLSCLTELAIKFPRTRRLVIADDDIEARLI
                     GSLSPSPLDGVLSKASTLEIFHQELFLSLNGVRQATDRLNNQWYINQSRTLSPTEREI
                     LRFMSRGYSMTQIAEQLKRNIKTIRAHKFNVMSKLGVSSDAGLLEAADILLCMRHCEA
                     INVLHPY"
     gene            complement(1694..2482)
                     /gene="fhuF"
                     /locus_tag="IRB70_004881"
     CDS             complement(1694..2482)
                     /gene="fhuF"
                     /locus_tag="IRB70_004881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore-iron reductase FhuF"
                     /protein_id="HBC0634677.1"
                     /translation="MAYRSAPLYEDIIWRTHLQPQDAGLAQAVRATIAEHREHLLEFI
                     RLDEPAPLRAMTLAQWSSPNTLSSLLAVYSDHIYRNQPTMIRENKPLISLWAQWYIGL
                     MVPPLMLALLTQEKALDVTPEHFHVEFHETGRAACFWVDVCEDKNATLHSPQQRMETL
                     ISQALVPVVQALEATGEINGKLIWSNTGYLINWYLTEMKQLLGEATVESLRHALFFEK
                     TLTNGEDNPLWRTVVLRDGLLVRRTCCQRYRLPDVQQCGDCTLK"
     gene            2623..2859
                     /locus_tag="IRB70_004882"
     CDS             2623..2859
                     /locus_tag="IRB70_004882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313355.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1435 domain-containing protein"
                     /protein_id="HBC0634678.1"
                     /translation="MLQRMLGSGWGVLLPGLLIAGLMYADLSPDQWRIVILMGLVLTP
                     VMLYHKQLRHYILLPSCLALIAGIMLMIVNLNQG"
     gene            complement(2898..2984)
                     /locus_tag="IRB70_004883"
     tRNA            complement(2898..2984)
                     /locus_tag="IRB70_004883"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(2948..2950),aa:Leu,seq:cag)
BASE COUNT          796 a          641 c          740 g          810 t
ORIGIN      
        1 gaagggatat cagttaatta taaattaaat gaatgagaac tctgtttttc attaagtatt
       61 tctaacaact taatgtagat attttaaatg tctccaggct atttcaccag gttatcattt
      121 gatgctaacc ttctgacaca tgctgtggag ttgttgtgca gcaggagtat gctgatatga
      181 aagtgaatgc taaggataat ttattcgctt aatctattaa tttgctggaa acatttaagg
      241 aatgaatatc ctgaataaac catcatgatt tttagacagt ggatgtggag gaaatatgtt
      301 gccaggatgc tgcaaaaatg gaattgttat cagtaaaata cctgttatgc aagcagggtt
      361 aaaagaggtc atgaggactc acttccctga atatgaaata atatccagcg cctctgcgga
      421 ggaccttacc ttattacaat tacgtcgttc cggattagtc attgctgatt tagccggtga
      481 aagtgaagat ccacgttctg tttgtgaaca ttattattct ttaatctcac aatatcggga
      541 aattcactgg gttttcatgg tgtcacgctc ctggtattcc caggcagtag aactgctcat
      601 gtgccctacg gcgacgttat tgtctgatgt tgaacccatt gagaatctgg tcaagaccgt
      661 acgttccggc aatacgcacg cagagcgtat cagcgccatg ctgacctctc cggcaatgac
      721 tgaaactcat gattttagct atcgctccgt cattctcact ctttcagagc gcaaggtact
      781 gcggctatta ggtaaaggat ggggcatcaa ccagatagct tcattgctta agaaaagtaa
      841 taaaactatc agcgcccaaa aaaacagtgc gatgcgtcga ctggcaattc acagcaacgc
      901 tgaaatgtat gcatggataa atagcgcgca gggtgcaaga gaacttaact tgccttctgt
      961 ttatggagat gccgcagaat ggaacacagc cgaattaaga agagaaatgt cgcactcata
     1021 gaaaaatgcg tcatgagcag tatcggtatt gagagtttat tcagaaagtt tgcaggtaac
     1081 ccttataagc tccataccta taccagtcag gagtcatttc aggatgccat gtcgcggatc
     1141 tcgtttgcgg cggtcatttt ttctttttct gccatgagaa gtgaacgcag agagggatta
     1201 tcttgcctga ctgaactggc gattaagttt ccgcgtaccc gacgtttagt tattgcggat
     1261 gatgatattg aagctcggct gatcggttca ttgtcgccat caccgctgga cggtgtatta
     1321 agtaaagcgt caacgctgga gatttttcat caggaactct ttttgtcatt aaatggtgta
     1381 cgtcaggcga ccgaccgact gaacaatcag tggtacatta accaaagccg gacgctaagc
     1441 ccgacggaga gagaaatatt gcgctttatg tcgcgtggct actcaatgac acaaattgcc
     1501 gagcagctta aacgcaatat caaaacgatc cgtgcacata aatttaatgt gatgtcgaaa
     1561 ctgggcgtca gttctgatgc agggttgttg gaggccgcag atattctgtt atgtatgcgg
     1621 cattgcgaag caattaatgt gttgcatccc tattaatttg catgatgccg ggtttacttc
     1681 cccggcagtg ctttcatttc agcgtacaat cgccacattg ctgcacatcc ggtaagcgat
     1741 aacgctggca gcaagtgcgg cgcaccagca ggccgtcgcg cagcaccacg gtacgccaga
     1801 gtggattatc ttcaccgttc gtgagcgttt tctcaaaaaa gagggcatgg cgcagcgatt
     1861 caaccgtcgc ctcgccgagt agctgtttca tctcagtcag ataccagttg atcaaataac
     1921 cggtattgct ccagataagt ttaccgttaa tctctcccgt tgcttctagt gcctgcacaa
     1981 ccggaacaag cgcctggctg attaacgttt ccattcgctg ctgcggcgaa tgtagtgttg
     2041 cgtttttatc ttcacacaca tcgacccaga aacaggcggc gcgtccggtt tcgtgaaact
     2101 caacgtggaa atgttccggc gtcacatcta atgctttttc ctgcgtcagc agcgccagca
     2161 ttaatggtgg caccatcagg ccgatatacc attgtgccca cagtgagatc agcggcttgt
     2221 tctcgcggat catcgttggt tggttgcggt agatatgatc ggaatagacc gccagtaggg
     2281 aacttagcgt attcggtgat gaccattgcg ccagcgtcat ggcgcgaagc ggggcgggtt
     2341 catccagacg gataaactcc agcaaatgtt cacgatgttc ggcgatcgtc gcacgtacgg
     2401 cttgtgcaag cccagcatcc tgtggctgga gatgcgttcg ccagatgata tcttcataga
     2461 gcggtgcgga acgataggcc ataatcggga tagtaatcta aatgataatg attgctaatc
     2521 ctagcgatag gtttacccga tagcaaggga tttctctggc ttgcaaatga taaaaattat
     2581 catatgatat tggttatcat tatcaatgaa agagatgaaa ccatgttgca acgtatgctg
     2641 ggcagtggct ggggagtgtt gctgccggga ttgctgattg cagggctgat gtatgcggat
     2701 ttatcgccgg atcagtggcg gattgtcatt ctgatgggat tagtattgac gcctgtgatg
     2761 ctgtatcaca aacagttgcg gcattacatt ttgctaccat cgtgcctggc gcttattgct
     2821 ggcatcatgc tgatgatagt gaatttgaat cagggatgac aaaacaggga agaaacaaga
     2881 aaggaagtaa agataattgg tgcgaggggg gggacttgaa cccccacgtc cgtaaggaca
     2941 ctaacacctg aagctagcgc gtctaccaat tccgccacct tcgcaca
//
LOCUS       DADXDL010000217         2972 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.218, whole genome shotgun sequence.
ACCESSION   DADXDL010000217 DADXDL010000000
VERSION     DADXDL010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2972
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.218"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>2972
                     /locus_tag="IRB70_004884"
     CDS             <1..>2972
                     /locus_tag="IRB70_004884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="RHS repeat protein"
                     /protein_id="HBC0634679.1"
                     /translation="PGWKMPADIRLQLRDNTLILSDNGGRSLYFEHLFPGEDGYSRSE
                     SLWLVRGGVAKLDEGHRLAALWQALPEELRLSPHRYLATNSPQGPWWVLGWCERVPEA
                     DEVLPAPLPPYRVLTGLVDRFGRTQTFHREAGGEFSGEITGVTDGAGRHFRLVLTTQA
                     LRAEEARQKAISGGTEPSAFPDTLPDYTEYGRDNGIRLSAVWLTHDPEYPENLPAAPL
                     VRYGWTPRGELAVVYDRSNTQVRSFTYDDKYRGRMVAHRHTGRPEIRYRYDSDGRVTE
                     QLNPAGLSYTYQYEKDRITITDSLDRREVLHTAGEGGLKRVVKKEHADGSVTQSQFDA
                     VGRLKTQTDAAGRTTEYSPDVVTGLITRITTPDGRASAFYYNHHSQLTSATGPDGLEI
                     RREYDESGRLIQETAPDGDITRYRYDNPHSDFPCATEDATGSRKTMTWSRYGQLLSFT
                     DCSGYQTRYDHDRFGQMTAVHREEGLSQCRAYDSRGQLIAVKDTQGHETRYEYNIAGD
                     LTAVIAPDGSRNGTQYDAWGKAIRTTQGGLTRSMEYDAAGRVIRLTNENGSHTTFRYD
                     VLDRLIQETGFDGRTQRYHHDLTGKLIRSEDEGLVTHWHYDEADRITQRTVNGETAEQ
                     WRYDERGWLTQISHLSEGHRVTVHYGYDEKGRLTGERQTVHHPQTEALLWQHETRHAY
                     NAQGLANRCIPDNLPAVEWLTYGSGYLAGMKLGDTPLVEYTRDRLHRETLRSFGRYEL
                     TTAYTPAGQLQSQHLNSLQYDRDYTWNDNGELIRISSPRQTRSYSYSDSGRLTGVHTT
                     AANLDIRIPYATDPAGNRLPDPELHPDSTLSMWPDNRIARDAHYLYRYDRHGRLTEKT
                     DLIPEGVIRTDDERTHRYHYDSRHRLVHYTRTQYAEPLVESRYLYDPLGRRVAKRVWR
                     RERDLTGWMSLSRKPEVTWYGWDGDRLTTIQNDRTRIQTVYQPGSFTPLIRVETATGE
                     QAKTQRRSLADALQQSGG"
BASE COUNT          674 a          911 c          930 g          457 t
ORIGIN      
        1 gccccggctg gaaaatgcct gcggatatcc gcttacagct gcgcgataac acactgatac
       61 tcagtgataa cggcggcaga agcctgtatt ttgagcacct gtttcccggt gaggacggtt
      121 acagccgcag cgagtcactc tggctggtgc gcggcggcgt ggcgaaactg gatgaaggtc
      181 accggctggc cgcactctgg caggcgctgc cggaagagct tcgcctgagt ccgcatcgtt
      241 atctggcgac gaacagtcca caggggccgt ggtgggtact cggctggtgt gagcgggtgc
      301 cggaggcgga tgaggtgctg cctgcgccgc tgccgccgta ccgggtactg accgggctgg
      361 tggaccgctt cgggcgcaca cagacgttcc accgtgaggc tggcggcgaa ttcagcggcg
      421 aaatcaccgg cgtgacggat ggcgcaggcc gtcacttccg gctggtactg accacgcagg
      481 cgctgcgggc agaagaggcc cggcagaagg ccatttccgg cgggacggaa ccgtccgctt
      541 ttcctgatac cctgccggac tacacggaat atggccggga caacggtatc cgtctgtctg
      601 ccgtgtggct gacacacgac cctgaatacc cggagaattt acctgccgcg ccgctggtgc
      661 gctatggctg gacgccacgc ggcgaactgg cggtggtgta tgaccgcagc aatacacagg
      721 tgcgcagctt tacttacgat gataaatacc ggggccggat ggtggcgcac cgtcacacgg
      781 gccggccgga aatccgttac cgttacgaca gtgacgggcg ggtgacagaa cagctaaacc
      841 cggcaggctt aagctacacg tatcagtatg agaaagaccg catcaccatc accgacagcc
      901 tggaccgccg tgaagtcctg cataccgcag gcgaaggcgg cctgaagcgg gtggtgaaaa
      961 aggaacacgc ggacggcagc gtcacgcaga gtcagtttga cgcggtgggc aggcttaaga
     1021 cacagacgga tgccgcaggc cggacaacag aatacagccc ggatgtggtg acgggcctca
     1081 tcacgcgcat caccacgccg gatggcaggg catcggcgtt ttactataac caccacagcc
     1141 agttaacgtc agccaccggg cctgacgggc tggaaatacg ccgggaatat gatgaatccg
     1201 gccgtctgat tcaggaaacc gcccctgacg gcgatatcac ccgctaccgt tatgataatc
     1261 cacacagtga cttcccctgc gcaacggaag atgccaccgg cagccggaaa accatgacgt
     1321 ggagccgtta cggtcagttg ctgagcttca ccgactgttc cggctaccag acccgttatg
     1381 accatgaccg cttcgggcag atgacggcgg tgcaccgcga ggaaggcctg agccagtgcc
     1441 gcgcatacga cagccgtgga cagttaattg ccgtgaaaga cacgcagggc catgaaacgc
     1501 ggtatgaata caacatcgcc ggtgacctga ccgccgtcat tgccccggac ggcagcagaa
     1561 acgggacaca gtacgatgcg tggggaaagg ccatccgtac cacgcagggc gggctgaccc
     1621 gcagtatgga atacgatgct gcaggacggg tcatccgcct gacaaacgaa aacggcagcc
     1681 acaccacctt ccgttacgat gtactcgacc ggctgataca ggaaaccggc tttgacggcc
     1741 gcacacagcg ttaccaccac gacctgaccg gcaaacttat ccgcagcgag gatgaggggc
     1801 tggtcaccca ctggcactat gacgaagcag accgcatcac gcagcgaacg gtgaatggtg
     1861 aaaccgcaga acagtggcgg tacgacgaac gcggctggct gacacaaatc agccatctca
     1921 gcgaagggca ccgggtgacg gtgcattacg ggtatgatga gaaaggccgc ctgaccggtg
     1981 agcgccagac ggtgcatcat ccgcagacgg aagcactgct ctggcagcat gagaccagac
     2041 atgcgtacaa cgcgcagggg ctggcgaacc gctgtatacc ggacaacctg cccgccgtgg
     2101 aatggctgac ttatggcagt ggttacctgg cagggatgaa actcggcgac acaccgctgg
     2161 tggagtacac ccgcgaccgc ctgcaccggg aaacgctgcg cagcttcggc cgttatgaac
     2221 tcaccaccgc ttatacccct gccgggcagt tacagagcca gcacctgaac agcctgcagt
     2281 atgaccgcga ttacacctgg aacgacaacg gcgaactcat tcgcatcagc agcccgcgcc
     2341 agacccggag ttacagctac agcgactccg gcaggctgac cggcgttcac accaccgcag
     2401 cgaacctgga tatccgcatc ccgtatgcca cggacccggc aggtaaccgc ctgcccgacc
     2461 cggagctgca cccggacagc accctcagca tgtggccgga taaccgtatc gcccgtgacg
     2521 cgcactatct ttaccggtat gaccgtcacg gcaggctgac ggagaaaacc gacctcatcc
     2581 cggaaggggt tatccgcacg gatgatgagc ggactcaccg gtaccattac gacagccggc
     2641 accggctggt gcactacacg cggacacaat atgcagagcc gctggtcgaa agtcgctatc
     2701 tttacgaccc gctgggccgc agggtggcaa aacgggtgtg gcggcgtgaa cgggacctga
     2761 cgggctggat gtcgctgtca cggaaaccgg aagtgacctg gtacggctgg gacggcgacc
     2821 gcctgaccac gatacagaac gacagaaccc gcatccagac ggtttatcag ccggggagct
     2881 tcacaccact catcagggtc gaaaccgcca ccggtgagca ggcgaaaacg cagcgccgca
     2941 gcctggcgga tgcgcttcag cagtccggcg gc
//
LOCUS       DADXDL010000218         2898 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.219, whole genome shotgun sequence.
ACCESSION   DADXDL010000218 DADXDL010000000
VERSION     DADXDL010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2898)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2898)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2898
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.219"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..2784)
                     /gene="yfaL"
                     /locus_tag="IRB70_004885"
     CDS             complement(<1..2784)
                     /gene="yfaL"
                     /locus_tag="IRB70_004885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AIDA-I family autotransporter adhesin YfaL/EhaC"
                     /protein_id="HBC0634680.1"
                     /translation="MRIIFLRKEYLSLLPSMIASLFSANGVAAVIDSCQGYDIKASCH
                     ASRQSLSGNMQDWSIADGQWLIFSGMANNASGGAVFLQQSAEFTISPQNETGMTLFAD
                     NSVSGEYNNGGAIFAKENSTINLANVIFDSNVAGGYGGAIYSAGTNDTGAADLRVTNA
                     VFHNNIANDGKGGAIYTINNDVYLSDDAFNNNQAYTSTSYSDGDGGAIDVTDNSTDNT
                     HLSGKTIINNTSFTNNYAEGYGGAIYTSSTTSPYLIDISVDDNYDQNNGVMIDENNSA
                     SGYDHSATAAAGGFMYIGHSVAEFNIAADKTLVIGNTSNDGAIDSLAGTGVIVKEGAG
                     ELVLNADNNAFTGEMSIQNGEVTLGRSDELMNVGDTHCQSDPQDCFGLMVGSTVHSEY
                     QAELNVGNTQQTFVHSLTGFANGILNIDAGGNVTVNQGGFSGSIQGEGQLTVAQDGSY
                     LLTGAQSMALTGDIVVEDNAVLSLAGNQADLRAMQSDPQSIVLNGGVLDLSDFTTWDG
                     DSSYNDGLQISGSGGTVIGSNDVVDISSGDDLHIGGSDASQNGVYVVINAGDQRVTLA
                     NNNGYLGNTQIASGTLEVSDNSQLGDTRYNRSVIFTDPQQHSEMDVTTDVDTRSATTG
                     QGRNIEMRADGEIHVEDGVDTQWGGLMADSTGQQLESVSTLTKSGGGTLELTASGTAT
                     SAVRVEDGTLKGEAENIIPYVSSLWVGEDGVFETGQNQDIRSIDATSGGDIDITDGTV
                     LRLTQQDTNQVLDASLFSGDGTLVNATDGVTLTGELNTNLETDSLTYLSDVTVNGNLT
                     NTSGAISLQNGVAGDTLTVNGDYTGGGTLLLDSELNGDDSASDQLVLNGNTAGNTAVV
                     INPITGIGEPTSTGIKVVDFAADPTQFQNNAQFRLAGSGYVNMGAYDYTLVEDNNDWY
                     LRSQEVTPTPPPDP"
BASE COUNT          707 a          796 c          610 g          785 t
ORIGIN      
        1 cggatcgggc ggcggcgtcg gagtgacttc ttgcgatcgc agataccagt cgttgttatc
       61 ttccaccagc gtatagtcat acgcccccat attgacgtag ccgcttcctg ccagacggaa
      121 ctgcgcattg ttttgaaact gcgtgggatc agctgcgaaa tcaaccactt taatacctgt
      181 agatgtcggc tcaccaatac ccgtaatggg gttaattacc acggccgtgt tgccagcagt
      241 attaccgttc aataccagtt ggtcacttgc cgagtcatcg ccgtttaatt cgctgtcgag
      301 cagtagcgta ccgccgccgg tataatcacc atttaccgtc agcgtgtcgc cagcgacgcc
      361 attttgcagg ctaatcgcac cggacgtatt ggtcagattg ccattaaccg tcacgtcgga
      421 aagataagtc aggctgtcag tttcaaggtt ggtattaagc tcgcctgtca gcgtcacgcc
      481 atcggtggca ttcaccaacg taccgtcgcc gctaaacagc gaggcatcca gcacctggtt
      541 cgtatcctgc tgcgtcaatc gcaacacagt accatcggtt atgtcgatat cgccgccaga
      601 ggtggcatcg attgagcgaa tatcctgatt ttgcccggtt tcaaaaacac cgtcttcccc
      661 cacccacagt gaagaaacat aaggaataat attctccgct tcacctttta gcgttccgtc
      721 ctccacacgt accgcagacg tcgcagtgcc gctggcggtc aactccagcg taccgccgcc
      781 acttttagtc aacgtgctta cgctctccag ttgttgcccg gtactatccg ccatcaaccc
      841 gccccattgc gtatctacgc catcctcaac gtgtatttcg ccatcagcgc gcatttcaat
      901 attcctgccc tgacctgttg tagccgagcg agtgtcaaca tcagtcgtca catccatttc
      961 actgtgttgt tggggatctg tgaagatcac tgaacggttg tatcttgtgt cccccaattg
     1021 cgaattatcg ctgacttcaa gcgtaccgga ggcgatttgc gtattaccga gataaccgtt
     1081 gttattcgcc agcgttacgc gctgatcccc cgcattaatg acgacataaa cgccattctg
     1141 gctggcatca ctgccgccaa tatgtaaatc atcgccactg ctgatatcaa cgacatcatt
     1201 actgccaatc actgtccccc cgctgccgct gatttgcaga ccgtcattgt atgagctatc
     1261 gccatcccag gtggtgaaat cagagagatc caatactccg ccatttagca cgatcgattg
     1321 cggatcgctc tgcattgccc gtaaatcggc ctgattcccc gctagcgaca atacggcgtt
     1381 atcttccacc acaatatcgc cggttaatgc catcgactgc gcccctgtca ggagatagct
     1441 gccatcttgc gctaccgtca actgtccttc accctgaatc gagccggaaa aaccgccctg
     1501 gtttacggta acattgccgc ctgcgtcgat attcaaaatg ccattagcaa aaccggttaa
     1561 tgagtgcaca aacgtttgtt gtgtattgcc aacattcagt tctgcctgat actcagaatg
     1621 aacagtgctg ccgaccatca aaccaaagca atcctgcgga tcgctctgac agtgcgtgtc
     1681 gccgacattc attaactcat cgctgcgccc caacgtcacc tcgccattct ggatactcat
     1741 ctcgccggta aacgcattat tgtcggcatt gaggactaac tctcccgctc cctctttcac
     1801 gatgactccc gttccggcaa gagaatcaat cgcgccatcg ttgctggtat tgcctattac
     1861 cagcgtttta tcggcggcaa tgttgaattc agccacacta tgaccgatat acataaagcc
     1921 ccccgccgct gccgtcgccg aatggtcata tcccgaggcg ctgttatttt catcaatcat
     1981 cacaccattg ttttggtcat aattatcatc aacagaaata tcaataagat acggggatgt
     2041 ggtgctgctg gtataaattg ctccgccata accttctgca tagttattgg taaaggaggt
     2101 attattaatt atcgtttttc ctgaaagatg tgtgttatcc gtactattat ccgtaacatc
     2161 aatggcaccg ccgtccccat cactatagct ggttgatgta tatgcctggt tattattaaa
     2221 agcatcatca cttaaataga cgtcattatt gatggtataa attgcaccgc ctttgccgtc
     2281 attagcgatg ttattgtgaa atacggcgtt agtgacacgt aaatcggcgg caccggtatc
     2341 attggtaccg gcagaataga ttgctccgcc atagcctcct gcaacattac tgtcgaaaat
     2401 aacattcgca agatttatcg ttgagttttc tttagcaaag atagccccac cattattata
     2461 ttcgccacta accgagttat cagcaaacag ggtcatccct gtttcatttt gtggtgaaat
     2521 cgtaaattca gcactttgct gcaaaaatac tgcgccaccg ctggcattat tggccatacc
     2581 cgaaaaaatc aaccattgcc catccgcgat gctccagtcc tgcatattgc ctgaaaggct
     2641 ttgcctgctg gcgtgacaac tcgctttgat atcatatccc tgacatgaat caatgaccgc
     2701 cgcgacaccg ttagcagaga aaagagacgc aatcattgac gggagtaaag ataaatactc
     2761 cttgcgtaga aaaataatcc gcatattaat ctgaccatca ttttctataa gacggcatat
     2821 ttaatcgcat tatacgatat gggttatttt tcttttgtaa attgttcaac ccagtgtaat
     2881 ggctattttg ttattatt
//
LOCUS       DADXDL010000219         2830 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.221, whole genome shotgun sequence.
ACCESSION   DADXDL010000219 DADXDL010000000
VERSION     DADXDL010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2830
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.221"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..957)
                     /locus_tag="IRB70_004886"
     CDS             complement(<1..957)
                     /locus_tag="IRB70_004886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416078.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF968 domain-containing protein"
                     /protein_id="HBC0634681.1"
                     /translation="MRVLLRPVLVPELGLVVLKPGRESIQIFHNPRVLVEPEPKSMRN
                     LPSGVVPAVGQPLAEDKTLLPFFSNERVIRAAGGVGALSDWLLRHVTSCQWPNGDYHH
                     TETVIHRYGTGAMVLCWHCDNQLRDQTSESLELLAQQNLTAWVIDVIRHAISGTQERE
                     LSLAELSWWAVCNQVVDALPEAVSRRSLGLPAEKICSVYRESDIVPGEQTATSILKQR
                     TKNLAPLPHAHQQQNPPQEKTVVSIAVDPESPESFMKRPKRRRWVNEKYKRWVKTQPC
                     ACCGKPADDPHHLIGHGQGGMGTKSHDIFTLPLCREHHNELHA"
     gene            complement(959..1237)
                     /locus_tag="IRB70_004887"
     CDS             complement(959..1237)
                     /locus_tag="IRB70_004887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634682.1"
                     /translation="MARNVKYYNSDNSPVLACTHERYSHAFKSEWFQHPPCTEEQAEW
                     IIQCYRRRGYEVKKALSLDYRHWIISVRLPYSERPPRASRTFQQRIWR"
     gene            complement(1304..1555)
                     /locus_tag="IRB70_004888"
     CDS             complement(1304..1555)
                     /locus_tag="IRB70_004888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634683.1"
                     /translation="MMNIEELRKIFCEDGLYAVCVENGNLVSHYRIMCLRKNGAALIN
                     FVDGRVTDGFILREGEFVTSLQALKEIGIKAGFSAFAEE"
     gene            complement(1772..1927)
                     /gene="hokD"
                     /locus_tag="IRB70_004889"
     CDS             complement(1772..1927)
                     /gene="hokD"
                     /locus_tag="IRB70_004889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system toxin HokD"
                     /protein_id="HBC0634684.1"
                     /translation="MKQQKAMLIALIVICLTVIVTALVTRKDLCEVRIRTGQTEVAVF
                     TAYEPEE"
BASE COUNT          738 a          703 c          638 g          751 t
ORIGIN      
        1 cgcatgaagc tcgttgtgat gctcccgaca cagcggtagc gtgaaaatat cgtgagattt
       61 tgtccccatt ccgccctgac catgaccaat caggtgatgg ggatcgtcgg ctggcttacc
      121 acaacacgca cacggctgtg tcttcaccca gcgtttgtat ttctcgttaa cccagcggcg
      181 acgtttaggt cgtttcatga aagattccgg agactcagga tcaacggcaa tgctgaccac
      241 cgtcttttcc tgtggtgggt tctgttgctg gtgggcgtga ggcagcggcg caagattttt
      301 tgtgcgctgt ttcagtatgc tggtggcggt ctgctctccc ggtacgatgt cgctttcgcg
      361 gtacaccgag cagatttttt ccgctggtaa tcccagcgaa cgacgcgata cagcctcagg
      421 tagtgcatcc accacctgat tgcagaccgc ccaccaggat aattcagcca aagataattc
      481 ccgctcctgc gtaccgctta ttgcgtgacg gatgacgtca atcacccatg ctgtcagatt
      541 ttgttgagca agcagctcca gtgattccga tgtctggtca cgcagttggt tgtcgcagtg
      601 ccaacacaac accattgcgc cggtaccata acggtgaatg actgtttcag tgtgatggta
      661 atctccatta ggccactggc aggatgtaac atgacgtaat agccagtcag acaatgcgcc
      721 aacgccgcca gcagcacgaa tcacccgttc gttactaaaa aacggcagca atgttttgtc
      781 ttccgccagc ggctggccaa cggcaggaac gactccggat ggcagattac gcatgctttt
      841 tggttccggt tccaccagca ctcgaggatt atgaaatatc tgtatggatt cacggcccgg
      901 cttaaggacc accagcccaa gctcaggcac cagaacaggt ctaagtaata cccgcacgtt
      961 acctccagat ccgttgctgg aaagtgcggg acgcacgtgg tgggcgttcg gagtaaggca
     1021 atctgactga gattatccag tgacggtagt cgagactaag ggctttctta acctcgtatc
     1081 cgcgcctgcg gtaacactga attatccatt cagcctgctc ttcagtgcat ggagggtgtt
     1141 ggaaccattc agacttgaat gcgtgagaat accgctcgtg cgtgcaggca agaacgggcg
     1201 aattatcaga attgtaatat tttacgttgc gtgccatcgg ttttctccgg tggcacggtg
     1261 ttactcagcg ggagttcagc cccgcgcaag attgtagatg agtttattct tctgcaaaag
     1321 ctgaaaagcc tgcttttatt ccgatctctt tcagtgcctg taatgaagtg acaaactcac
     1381 cttcgcgcaa gataaatccg tctgtcactc gaccatccac aaaattaatt aacgcagccc
     1441 cattctttcg caaacacata atgcggtaat gactaacaag atttccattt tcaacgcaca
     1501 ccgcatagag gccatcttca caaaaaattt tacgcagttc ttcgatgttc atcatcagaa
     1561 tccttccgga taattagctc tcccctttaa gggaccatcc ctcttatccc tgcgcgctac
     1621 ttaagtattt ttgattctat tccggcaccg tccagaactt caaacgcgtt gaaaataaaa
     1681 acaaaaaccc gccgaagcgg gttaagtgcg ggtgcgttga ggatgcctgc cacatcagag
     1741 gtggcgaggg atttctccct cgccgggtct cttactcctc aggttcgtaa gctgtgaaga
     1801 cagcgacctc cgtctgcccg gttcggattc gtacctcgca gaggtctttc ctcgttacca
     1861 gtgccgtcac tatgacggtt aaacagatga cgatcagggc gattaacatc gccttttgct
     1921 gcttcatagc ctgcttctcc ttgcctttcg gcacgtaaga ggctaaccta catgtgtcta
     1981 gcatgaaatt ggcctcagat taatgttaag cgtcttgcag gacgcgtaat gttaactggg
     2041 gcttttctct atctgccgtt ggtgttcatg cccgaggcag atagcctcaa gcacccgcag
     2101 ccattctact taactaccgt tacctcgcca atgtgaaatc agtcagaaag gcgatccata
     2161 agaacaatag caagacaata aatcgccatt acagccgtaa tagccagcgc acatttgaga
     2221 accagcacca caacctcctg tattggacgt acaccagtcc tgatgaatat gaggctgtct
     2281 cgtcagtgat tcaatacaac tattgggtat agtttctctg attttttctg tggaaatggg
     2341 gctcaaccac tagtcattta atacgcaaag tccgacacaa gctaaccttc tagtccgctt
     2401 tgagcgatga gcggacatcg actttaaaaa acactagcgt aaacaggaag gcagttatga
     2461 tccagaatga atactcacta cctctttgac taaaatgatg ataagtgctc atttgatgat
     2521 aattaacatg ttttttaata attaaagcta acataataat ttaacgaata ttctttgctt
     2581 tctgaataat aaacctagag caaactaaat gacatcacca ggacttaaca ccatagggtt
     2641 ggtttcgaat attcttggcg tgatattaat ttttcttttg attaccacaa tcctctcata
     2701 atgagggagt gtcactggca ttggaagata atacgcaatt gaatgatgga actactgtca
     2761 aataaaagaa cttaaaaaca aaaaaagaag tatatttaca atatctttcg tatacttagc
     2821 gttagcatta
//
LOCUS       DADXDL010000220         2742 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.223, whole genome shotgun sequence.
ACCESSION   DADXDL010000220 DADXDL010000000
VERSION     DADXDL010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2742
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.223"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1355
                     /locus_tag="IRB70_004890"
     CDS             <1..1355
                     /locus_tag="IRB70_004890"
                     /EC_number="4.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutamate decarboxylase"
                     /protein_id="HBC0634685.1"
                     /translation="RFGAKAISTIAESKRFPLHEMRDDVAFQIINDELYLDGNARQNL
                     ATFCQTWDDENVHKLMDLSINKNWIDKEEYPQSAAIDLRCVNMVADLWHAPAPKNGQA
                     VGTNTIGSSEACMLGGMAMKWRWRKRMEAAGKPTDKPNLVCGPVQICWHKFARYWDVE
                     LREIPMRPGQLFMDPKRMIEACDENTIGVVPTFGVTYTGNYEFPQPLHDALDKFQADT
                     GIDIDMHIDAASGGFLAPFVAPDIVWDFRLPRVKSISASGHKFGLAPLGCGWVIWRDE
                     EALPQELVFNVDYLGGQIGTFAINFSRPAGQVIAQYYEFLRLGREGYTKVQNASYQVA
                     AYLADEIAKLGPYEFICTGRPDEGIPAVCFKLKDGEDPGYTLYDLSERLRLRGWQVPA
                     FTLGGEATDIVVMRIMCRRGFEMDFAELLLEDYKASLKYLSDHPKLQGIAQQNSFKHT
                     "
     gene            1724..2548
                     /gene="gadX"
                     /locus_tag="IRB70_004891"
     CDS             1724..2548
                     /gene="gadX"
                     /locus_tag="IRB70_004891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acid resistance transcriptional activator GadX"
                     /protein_id="HBC0634686.1"
                     /translation="MQPLHGNCLIAYARHKYILTMVNGEYRYFNGGDLVFADASQIQV
                     DKCVENFVLVSRDTLSLFLPMLKEEALKLHAHKKVPSLLVHHCTRDIPVFQEVAQLSQ
                     NKNLRYAEMLRKRALIFALLSVFLEDTQFIPLLLNVLQPNMRTRVCTVINNNIAHEWT
                     LARIASELLMSPSLLKKKLREEGTSYSQLLTECRMQRALQLIVIYGVSIKRVAVSCGY
                     HSVSYFIYVFRNYYGMTPTEYQERSAQELPNCGPAASMAAQGNFYGTDRSAEGIRL"
BASE COUNT          723 a          622 c          651 g          746 t
ORIGIN      
        1 cacgttttgg tgcaaaggcc atttctacta tcgcggagtc aaaacgattt ccgctgcacg
       61 aaatgcgcga tgatgttgca tttcagatta tcaatgatga attatatctt gatggcaacg
      121 ctcgtcagaa cctggccact ttctgccaga cctgggacga cgaaaacgtc cataaattga
      181 tggatttgtc gatcaataaa aactggatcg acaaagaaga atatccgcaa tccgctgcaa
      241 tcgacctgcg ttgcgtaaac atggttgccg atctgtggca tgcgcctgca ccgaaaaatg
      301 gtcaggccgt tggcaccaac accattggtt cttccgaggc ctgtatgctc ggcgggatgg
      361 cgatgaaatg gcgttggcgc aagcgtatgg aagccgcagg caaaccaacg gataaaccaa
      421 acctggtgtg cggtccggta caaatctgct ggcataaatt cgcccgctac tgggatgtgg
      481 agttgcgtga gatccctatg cgccccggtc agttgtttat ggacccgaaa cgcatgattg
      541 aagcctgcga cgaaaatacc atcggcgtgg tgccgacttt cggcgtgacc tacaccggta
      601 actatgagtt cccgcagccg ctgcacgatg cgctggataa attccaggcc gacaccggta
      661 tcgacatcga catgcacatc gacgccgcca gcggtggctt cctggcaccg ttcgtcgccc
      721 cggatatcgt ctgggacttc cgcctgccgc gtgtgaaatc gatcagtgct tcaggccata
      781 aattcggtct ggctccgctg ggctgcggct gggttatctg gcgtgatgaa gaagcgctgc
      841 cgcaggaact ggtgttcaac gttgactacc tcggcggtca gattggtact ttcgccatca
      901 acttctcccg cccggcgggt caggtgattg cacagtacta tgaattcctg cgcctcggtc
      961 gtgaaggcta taccaaagta cagaacgctt cctaccaggt tgccgcttat ctggcggatg
     1021 aaatcgccaa actggggccg tatgagttca tctgtaccgg tcgcccggac gaaggcatcc
     1081 cggcggtttg cttcaaactg aaagatggtg aagatccagg atacaccctc tacgacctct
     1141 ctgaacgtct gcgtctgcgc ggctggcagg ttccggcctt cactctcggc ggtgaagcca
     1201 ctgacatcgt ggtgatgcgc attatgtgtc gtcgcggctt cgaaatggac tttgctgaac
     1261 tgttgctgga agactacaaa gcctccctga aatatctcag cgaccacccg aaactgcagg
     1321 gtattgccca gcagaacagc tttaaacata cctgataaca taacgttgta aaaaccgaat
     1381 gcccaacctt taaaaaacag ctgggcattc ggttgcttat taatcgcaat aatatattgg
     1441 ctgtctattc atcgtgttga taagatatat gttatatgaa tgtttattaa atgtagcgat
     1501 tatatttaat gtaacgaaaa gggattattt gcttactatt aatttccctg cgttcttaaa
     1561 cacgtttttg tattataaat ccagtcatcc tgcccgtaga acatcacaca ttatcatcct
     1621 gttctcccgc ttcgtttaaa tttatttatc aatcaatttg acttaagagg gcggcgtgct
     1681 acattaataa acagtaatat gtttatgtaa tattaagtca actatgcaac cactacatgg
     1741 taattgtcta attgcgtacg caagacataa atatattctc accatggtta atggtgaata
     1801 tcgctatttt aatggcggtg atctggtttt tgcggatgca agccaaattc aagtggataa
     1861 gtgtgttgag aatttcgtat tagtttcaag agacacgctt tcattatttc tcccgatgct
     1921 caaggaggag gcattaaaac ttcatgcaca taaaaaagtt ccttcattac tcgttcatca
     1981 ctgtaccaga gatattcctg tttttcagga agttgcgcaa ctgtcgcaga ataagaatct
     2041 tcgctatgca gaaatgctac gtaaaagggc attaatcttt gcgttgttat ctgtttttct
     2101 tgaggatacg cagtttatac cgttacttct gaacgtgttg caaccgaata tgcgaacacg
     2161 agtttgtacg gtcatcaata ataatatcgc ccatgagtgg acattagccc gaatcgctag
     2221 cgaattgttg atgagtccaa gcctgttaaa gaaaaaattg cgcgaagaag gtacgtcata
     2281 ttcacagttg cttactgagt gtaggatgca gcgtgcttta caacttattg ttatatatgg
     2341 ggtttcaatt aagcgagttg cagtatcctg tggatatcac agcgtgtcgt atttcattta
     2401 cgtttttcga aattattatg ggatgacgcc cacagagtat caggagcgat cggcgcagga
     2461 attaccgaac tgtggcccgg cggcaagtat ggctgcgcaa gggaattttt acggcactga
     2521 ccgttctgcg gaaggaataa gattatagag ttttactcag acataaaaaa aacccggcat
     2581 aggggaccgg gaagaggata gtctgccgtc tccagactaa taaaccgtta taacactccc
     2641 tgttggcacg ggaaactttg tgctctcagt aagttaaata taacttttac tggaaataag
     2701 atcagccatt tttttataaa cataagctat acgctgtgcg aa
//
LOCUS       DADXDL010000221         2726 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.224, whole genome shotgun sequence.
ACCESSION   DADXDL010000221 DADXDL010000000
VERSION     DADXDL010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2726)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2726)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2726
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.224"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(91..1497)
                     /gene="gndA"
                     /locus_tag="IRB70_004892"
     CDS             complement(91..1497)
                     /gene="gndA"
                     /locus_tag="IRB70_004892"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBC0634687.1"
                     /translation="MSKQQIGVVGMAVMGRNLALNIESRGYTVSVFNRSREKTEEVIA
                     ENPGKKLVPYYTVQEFVESLETPRRILLMVKAGAGTDSAIDSLKPYLDKGDIIIDGGN
                     TFFQDTIRRNRELSAEGFNFIGTGVSGGEEGALKGPSIMPGGQKEAYELVAPILKQIA
                     AVAEDGEPCVTYIGADGAGHYVKMVHNGIEYGDMQLIAEAYALLKGGLALSNEELAQT
                     FTEWNEGELSSYLIDITKDIFTKKDEEGKYLVDVILDEAANKGTGKWTSQSSLDLGEP
                     LSLITESVFARYISSLKDQRVAASKVLSGPQAQPAGDKAEFIEKVRRALYLGKIVSYA
                     QGFSQLRAASDEYNWDLNYGEIAKIFRAGCIIRAQFLQKITDAYAQNAGIANLLLAPY
                     FKQIADDYQQALRDVVAYAVQNGIPVPTFSAAIAYYDSYRSAVLPANLIQAQRDYFGA
                     HTYKRTDKEGVFHTEWLE"
     gene            complement(1671..>2726)
                     /locus_tag="IRB70_004893"
     CDS             complement(1671..>2726)
                     /locus_tag="IRB70_004893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634688.1"
                     /translation="KDNSIKLDDVSGFRKGDIVRISSHESTLSFGFWVENYIQLSRII
                     KVDSLNKTLIIEHPISFHGELELCLASTNSVKARFGRPLFCCSDTIVRNTEVNTWDYW
                     IADSCTYNMLFENIYGSAKSVVYGNSYCYTTFKNIRIKFTGSVSELAFGSHFTTLEGI
                     YAISSNDGVSKKEMISWTEAGRNCTLSRFLLRINNNETPSTIIRISGHSNAIIRNGQI
                     FIFSNPNNILSVENYGNGQPECVNITYSNIDVYAKESINVFCDVFKANDTAAIEKVSF
                     HNVRYFGMKPKVALLRLRGTPLNTISGVDAIIYSKYGGDAKIAHAKENYIHLASVAYE
                     STTEDFSTNNVTYSKVN"
BASE COUNT          812 a          613 c          555 g          746 t
ORIGIN      
        1 cgtacaaata agatgacttt gatcagttta ttgtaggaaa aaacaataga taacagtcag
       61 gccaattggc ctgactgtgg tatataaaga ttattccaac cactcggtat ggaatacacc
      121 ttctttatca gtacgtttat aggtgtgcgc accaaagtaa tcacgctgag cctggatcag
      181 gttagctggc agaactgcgg aacggtagct gtcgtagtaa gcaatcgcgg ctgagaacgt
      241 cggtaccgga ataccattct gcaccgcata cgccacgaca tcacgcagcg cttgctgata
      301 gtcatcagcg atctgtttga agtatggcgc cagcaggagg ttagcaatac cagcgttttg
      361 cgcataagca tcggtgatct tttgcaggaa ctgcgcacga ataatgcagc cagcgcggaa
      421 aatcttagcg atctcgccgt agttcagatc ccagttgtat tcatcagaag cagcacgcag
      481 ctgggagaag ccctgagcat aggaaacgat tttaccgagg tacaacgcgc gacgcacttt
      541 ttcgataaat tcagctttat cacccgccgg ctgagcctgc ggaccactca gcactttcga
      601 agcagctaca cgctggtctt ttagcgaaga gatataacga gcaaatacgg actcggtgat
      661 cagagacaga ggttcgccga gatccagtga gctctggctg gtccacttac cggtaccttt
      721 gtttgctgct tcatcaagga tgacatcgac gaggtattta ccctcttcat cctttttagt
      781 gaagatatct ttggtaatat caatcaggta gctgctcagc tcgccttcgt tccattcagt
      841 gaaggtttgt gccaactctt cattggagag cgccagaccg cctttcaaca gcgcataagc
      901 ttcagcaatc agttgcatat cgccatactc gatgccgtta tgaaccatct tcacataatg
      961 accagcgcca tcagcaccga tataggtgac acaaggctct ccgtcttcag caaccgccgc
     1021 gatctgtttc agaatcggag caaccagctc ataggcttct ttttggccac ctggcataat
     1081 ggaaggccct ttcagagccc cctcttcacc accggaaaca ccggtaccga taaagttaaa
     1141 accttcggca gacagttcac ggttacgacg gatggtgtcc tggaagaagg tgttgccgcc
     1201 atcaatgatg atgtcgcctt tatcaaggta aggcttcagg gaatctatgg cgctatcggt
     1261 gccagccccg gccttcacca tcaacaggat acgacgtggt gtttcgaggg attcaacaaa
     1321 ctcttgtact gtgtaataag gaacgagttt cttgcctgga ttttcggcaa tcacttcttc
     1381 ggtcttttca cgggagcggt tgaatacgga gacggtataa ccacggcttt cgatgttcag
     1441 cgcaaggtta cgccccatca cagccatacc gacaaccccg atctgttgct tggacattac
     1501 atactcctgt caggtgtagt cactgcgaca cattcacagc ttaatgagac atctatccta
     1561 acgcaaataa agtgaggcgc ctagtttgta aaacccaaaa agttgcgcaa aatcgaatag
     1621 tataaagaaa cataggtaac tagagggaaa agaatgccaa atagaatcct ttaatttacc
     1681 ttagaatatg taacattatt tgtagaaaaa tcctctgtag ttgattcata tgcaacacta
     1741 gctaagtgaa tataattttc tttagcatgt gcaatttttg catcaccgcc atatttggag
     1801 taaatgatag cgtcaactcc tgagatggta ttcaaagggg ttccgcgaag tcgtaataaa
     1861 gcgaccttag gtttcatgcc aaagtatcta acattatgga aagatacctt ttcgatagca
     1921 gcagtgtcat tagctttaaa aacatcacaa aaaacattaa tgctttcttt agcataaaca
     1981 tcaatgtttg aataagtaat attcacacat tcgggctgac cattcccata attttcaacg
     2041 ctaagtatat tattcggatt tgagaaaata aaaatctgcc catttctaat gatggcattt
     2101 gaatgcccgg aaattctaat aatcgtactt ggtgtttcat tgttattaat tctgagcaaa
     2161 aatctagaaa gcgtacaatt tcttccagcc tccgtccagc tgatcatttc ttttttagaa
     2221 acaccatcat tagatgaaat cgcataaata ccttcaagag ttgtaaagtg cgagccaaat
     2281 gccaactcag agaccgagcc tgtaaattta attctgatat ttttaaaagt ggtgtaacaa
     2341 tagctgttgc catacacaac agatttagct gaaccatata tgttttcaaa aagcatatta
     2401 tatgtacagc tatctgcaat ccaataatcc caagtattaa cttcagtgtt acggacaatt
     2461 gtatctgagc aacaaaataa tggacgcccg aatcttgctt ttaccgagtt cgtagatgcg
     2521 agacataact caagctcacc atgaaaagaa ataggatgct caattatcaa ggttttattc
     2581 aaagaatcaa ctttgattat tcttgaaagc tgaatatagt tttcaaccca aaagccgaaa
     2641 ctcaatgtcg actcatgaga agatattctt actatatcac cttttctaaa accgctaaca
     2701 tcatcaagtt taattgaatt atcttt
//
LOCUS       DADXDL010000222         2690 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.225, whole genome shotgun sequence.
ACCESSION   DADXDL010000222 DADXDL010000000
VERSION     DADXDL010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2690)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2690)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2690
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.225"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..83)
                     /locus_tag="IRB70_004894"
     CDS             complement(<1..83)
                     /locus_tag="IRB70_004894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634689.1"
                     /translation="MELKKLMEHISIIPDYRQAWKVEHKLS"
     gene            complement(311..2419)
                     /locus_tag="IRB70_004895"
     CDS             complement(311..2419)
                     /locus_tag="IRB70_004895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion system tip protein VgrG"
                     /protein_id="HBC0634690.1"
                     /translation="MSTGLRFTLEVDGLPPDAFAVVSFHLTQSLSSLFSLDLSLVSQQ
                     FLSLEFAQVLDKMAYLTVWQGDDVQRRVKGVVTWFELGENDKNQMLYSIKVRPPLWRA
                     GLRQNFRIFQNEDIRSILGTILQENDVTEWSPLFSEPHPSREFCVQYGETDYDFLCRM
                     AAEEGIFFYEEHAQKSTDQSLVLCDTVRYLPESFEIPWNPNTRTEVSTLCISQFLYSA
                     QIHPSSVVTKDYTFKRPGWAGRFDQEGQHQDYQRTQYEVYDYPGRFKGAHGQNFACWQ
                     MDGWRNNAEVARGTSRSPEIWPGRRIALTGHPQANLNREWQVVASELHGEQPQAVPGR
                     SGSGTTLNNHFAVIPADRTWRPQPLLKPLVDGPQSAVVTGPAGEEIFCDEHGRVRVKF
                     NWDRYNPSNQDSSCWIRVAQAWAGTGFGNLAIPRVGQEVIVDFLNGDPDQPIIMGRTY
                     HQENRTPGSLPGTKTQMTIRSKTYKGSGFNELKFDDATGKEQVYIHAQKNMNTEVLNN
                     RTTDVINNHAETIGNNQVIAVTNNQIQTVGVNQIETVGSNQIIKVGSVQVETIGLVRA
                     LTVGVAYQTTVGGIMNTSVALMQSSQIGLHKSLMVGLGYDVKVGNNVTFTVGKTKKDD
                     TGQTAIYSAGEHLELCCGKARLVLTKDGQIFLNGTKIHLQGKEQVNGDSLLINWNCAA
                     SKSPPKTPDEKQDTPDMREY"
BASE COUNT          599 a          724 c          656 g          711 t
ORIGIN      
        1 tccgataatt tatgttccac tttccaggct tgtctgtaat cggggataat agaaatatgc
       61 tccatcaatt ttttaagttc cattttgttc tccttaatta tgtaaggagt atttgatcat
      121 gtataagcaa taaaaaacag cttcaggtaa tgaggaatat ctcaattttt aaacataaaa
      181 tgcgaattgt ttagtacaaa aagtgtactt ctgatgatct ttccctggct ggttttccgc
      241 tcatgattca attccttctt ctgtttattt ttaatgcttg tttgttactg aatactgaac
      301 aggtacggga tcagtactct ctcatatccg gcgtatcctg cttttcatca ggggtcttcg
      361 gtggggattt cgaggctgca cagttccagt taatcaacag tgagtcacca ttaacctgct
      421 ccttaccctg caaatgaatt tttgtgccgt tgagaaaaat ttgtccgtcc ttagtcagca
      481 ccagccttgc cttaccacag cagagttcca gatgctcacc ggcggagtaa atcgcggtct
      541 gcccggtatc atcctttttc gttttaccaa cggtgaaggt aacgttattt ccgactttga
      601 cgtcataacc cagcccgacc atcaacgatt tatgcaaacc gatctgcgag gactgcatca
      661 gggccaccga ggtgttcata atgccaccta ccgtcgtctg atacgccacg cccacagtca
      721 gcgcacgaac aagtccaatc gtttccacct gaacagagcc cactttaatg atctggttac
      781 tgcccaccgt ctctatctgg ttaacgccca ccgtctgtat ctgattgttg gtaaccgcaa
      841 tcacctgatt gttgccgatg gtctcagcat ggttgtttat cacatccgtg gtgcggttat
      901 tcagcacctc ggtgttcatg ttcttctgcg cgtggatgta gacctgttct ttccctgtcg
      961 catcgtcaaa cttcagttca ttaaacccgc tgcccttata ggtttttgaa cgaatggtca
     1021 tttgcgtctt tgttcccggc aggctgccgg gggtgcggtt ttcctggtgg taggtgcgcc
     1081 ccataataat cggctggtcc ggatcgccgt tgaggaagtc cacaatgacc tcctgaccca
     1141 cacgcggtat cgccaggtta ccaaacccgg tgcctgccca cgcctgtgcc acacggatcc
     1201 agcatgaact gtcctggttt gacgggttat aacggtccca gttaaatttc acccgcacgc
     1261 ggccatgttc atcacagaag atttcttctc ctgccggtcc cgtcacgacg gcgctctgcg
     1321 ggccgtccac cagcggtttc agcaacggct gtggccgcca tgttctgtct gccggtatta
     1381 ccgcaaagtg gttattcagc gtggtacctg aaccactgcg tcccggcacc gcctgcggct
     1441 gctcgccgtg cagttcactt gccaccacct gccattcccg gttcaggttc gcctgcggat
     1501 gccccgtcag cgcaattcgc cgtcccggcc atatctccgg cgaacggctt gttccgcgcg
     1561 ccacttctgc gttgtttcgc cagccatcca tctgccagca ggcaaagttc tgcccgtggg
     1621 cacccttgaa acgtccgggg tagtcataca cttcatactg tgtgcgctgg taatcctggt
     1681 gctggccttc ctgatcaaaa cgccctgccc agccgggtcg tttaaaggtg tagtctttgg
     1741 tcaccacgga agatgggtgg atttgtgcgc tgtagaggaa ctggctgatg catagggtgc
     1801 tcacctcggt acgggtgttc ggattccagg ggatctcaaa ggactccggc agataacgca
     1861 cggtgtcgca caggaccagg ctctggtcgg tacttttttg cgcgtgctcc tcataaaaga
     1921 agatgccttc ctccgccgcc atccggcaca ggaaatcgta atcggtttcg ccgtactgga
     1981 cacaaaactc acgggaagga tgcggctcgc tgaacagcgg actccactcc gtgacgtcat
     2041 tttcctgcag tatggtgccg aggatgcttc tgatgtcctc gttctggaag atacggaagt
     2101 tctgacgcag tcctgcccgc cacagcggcg ggcgcacctt tatgctgtac agcatctggt
     2161 ttttgtcgtt ctccccgagt tcaaaccagg tcaccacgcc tttcacccgg cgctgtacgt
     2221 catcgccctg ccataccgtc aggtaggcca ttttgtccag cacctgcgca aattcaaggg
     2281 agagaaactg ctgactgacc agagaaaggt caagggaaaa aagtgaagag agtgactggg
     2341 tgagatgaaa ggaaaccacc gcaaacgcgt ccggtggcag gccgtccact tccagcgtga
     2401 aacgtaatcc ggttgacata gcaacctccg tgaaaatgaa taataatccg cacatattgc
     2461 atgtacaaca tgtcgggcgg atgagataag cgagtcgaca tctggcgtta ccggggaata
     2521 tcagaaaaat gtcatggtta tgtgatgatt tagtctggga ttttacttca gagaaacggg
     2581 tgtctgttta gtcaacaaaa taatcacaaa cgcaacggat gggttctcga cgttattcac
     2641 gacaggctcg tacattacag cgagtaataa aaaacctgat atgcaaagtc
//
LOCUS       DADXDL010000223         2677 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.226, whole genome shotgun sequence.
ACCESSION   DADXDL010000223 DADXDL010000000
VERSION     DADXDL010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2677)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2677)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2677
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.226"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            428..571
                     /locus_tag="IRB70_004896"
     CDS             428..571
                     /locus_tag="IRB70_004896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416338.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YobF family protein"
                     /protein_id="HBC0634691.1"
                     /translation="MCGIFSKEVLSKHVDVEYRFSAEPYIGASCSNVSVLSMLCLRAK
                     KTI"
     gene            584..793
                     /gene="cspE"
                     /locus_tag="IRB70_004897"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
     CDS             584..793
                     /gene="cspE"
                     /locus_tag="IRB70_004897"
                     /gene_synonym="gicA"
                     /gene_synonym="msmC"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antiterminator/RNA stability
                     regulator CspE"
                     /protein_id="HBC0634692.1"
                     /translation="MAKIKGQVKWFNESKGFGFITPADGSKDVFVHFSAIQGNGFKTL
                     AEGQNVEFEIQDGQKGPAAVNVTAI"
     gene            959..1768
                     /gene="rlmA"
                     /locus_tag="IRB70_004898"
     CDS             959..1768
                     /gene="rlmA"
                     /locus_tag="IRB70_004898"
                     /EC_number="2.1.1.187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416336.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (guanine(745)-N(1))-methyltransferase"
                     /protein_id="HBC0634693.1"
                     /translation="MSFSCPLCHQPLSREKNSYICPLRHQFDMAKEGYVNLLPVQHKR
                     SRDPGDSAEMMQARRAFLDAGHYQPLRDAIVAQLRERLDEKATAVLDIGCGEGYYTHA
                     FADALPEITTFGLDVSKVAIKAAAKRYPQVTFCVASSHRLPFSDTSMDAIIRIYAPCK
                     AEELARVVKPGGWVITATPGPRHLMELKGLIYNEVHLHAPHAEQLEGFTLQQSDELCY
                     PMRLRGDEAVALLQMTPFAWRAKPEVWQTLAAKEVFDCQTDFNIHLWQRSY"
     gene            complement(1765..2331)
                     /gene="mntP"
                     /locus_tag="IRB70_004899"
     CDS             complement(1765..2331)
                     /gene="mntP"
                     /locus_tag="IRB70_004899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416335.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese efflux pump MntP"
                     /protein_id="HBC0634694.1"
                     /translation="MNITATVLLAFGMSMDAFAASIGKGATLHKPKFSEALRTGLIFG
                     AVETLTPLIGWGMGMLASRFVLEWNHWIAFVLLIFLGGRMIIEGFRGADDEDEEPRRR
                     HGFWLLVTTAIATSLDAMAVGVGLAFLQVNIIATALAIGCATLIMSTLGMMVGRFIGS
                     IIGKKAEILGGLVLIGIGVQILWTHFHG"
BASE COUNT          719 a          615 c          633 g          710 t
ORIGIN      
        1 gatttttttg cgcattcatc aatttttctt attttaaatt tacaatacca ttggggattg
       61 acttctcttt ggggtaattg gtggccgtta actgactgtt ttatgagaaa aagtgatata
      121 actttttatt cattgcatag cagaaaatgt gatattgcac gcactatgta ataacttctc
      181 ccactggcct ggaacaactg aacttattga actatgttag aaaatacgtc agtttaagta
      241 tctgcctgaa ctggcaaggt taagcacaat gatatatcgg cgcgtattcc gttgcataag
      301 tgtgcaaaaa aagtggaaga cgtatcgaga tttgtgcgtc tgatcgagac atgtttaaaa
      361 atggcttgcc ataattaacg ttgtatgtga taacagattt cgggttaaac gaggtacagt
      421 tctgtttatg tgtggcattt tcagtaaaga agtcctgagt aaacacgttg acgttgaata
      481 ccgcttctct gccgagcctt atattggtgc ctcatgcagt aatgtgtcag ttttatctat
      541 gttatgcctg cgggcgaaga aaacaatcta aggaattttt caaatggcaa agattaaagg
      601 tcaggttaag tggttcaacg agtctaaagg ttttggcttc attactccgg ctgatggcag
      661 caaagacgtg ttcgtacact tctccgctat ccagggtaat ggcttcaaaa ctctggctga
      721 aggtcagaac gttgagttcg aaattcagga cggccagaaa ggtccggcag ctgttaacgt
      781 aacagctatc tgatcgaatc cactgatctg aagtgtgaat acgcttcaat ctcgctataa
      841 agcctcgccg aatgcgaggc tttttacttt gctttatctt cgctccaggc gttcggatat
      901 ttgcccgccg cgtgattcgc gttacacttg cggcctttag tatcctgccg gagttgtcat
      961 gtcgttttcc tgtccacttt gccatcagcc tctttcgcgt gaaaaaaaca gctatatctg
     1021 tcccctgcga catcagtttg atatggcgaa agaagggtat gtcaatctgc tgcccgttca
     1081 gcataaacgg tctcgtgatc cgggcgacag cgcggaaatg atgcaagcac gccgcgcatt
     1141 cttagatgcc ggacattatc agccgctgcg tgatgcaatt gtcgcccaac tgcgggaacg
     1201 gcttgatgaa aaggccacgg cggtgctgga tattggctgt ggtgaagggt attacacaca
     1261 cgcatttgcc gatgcgctgc ccgaaatcac cacgtttggt ctggatgtct cgaaggtagc
     1321 gataaaagcg gcggcgaaac gctatccgca ggtcactttt tgtgttgctt ccagccaccg
     1381 tttgccgttt tccgatacca gtatggacgc cataatacgt atttacgcgc cgtgtaaagc
     1441 agaagaatta gcgcgcgtag tgaagcctgg cggttgggtc attactgcca cgccgggacc
     1501 gcgacatttg atggagctga aggggctgat ttacaatgaa gtacatcttc atgcaccaca
     1561 tgcagaacaa ctggaaggtt ttacattaca gcagagtgat gagttgtgtt atccgatgcg
     1621 tcttcgcggt gacgaagccg tcgcattatt gcagatgacg ccgtttgcct ggcgtgcgaa
     1681 gccagaagtc tggcaaacac tggcagcaaa agaagtgttc gactgccaga cggactttaa
     1741 tattcacctc tggcagcgtt cttattaacc gtggaagtgc gtccagagga tctggacgcc
     1801 gatgccgatc agcaccagcc cgccgagaat ttccgctttt ttcccaataa ttgagccgat
     1861 aaagcgacct accatcatcc ctaatgtcga cataatcaag gttgcacaac caatggccaa
     1921 tgcggtcgcg ataatgttga cctgaaggaa agcaagacca acacccacag ccatggcatc
     1981 caggctggtg gcaatcgcag tggttaccag taaccaaaaa ccgtgtcgac ggcgcggttc
     2041 ttcatcttca tcatctgcgc cacgaaaacc ctcaataatc attcgcccgc cgagaaatat
     2101 cagcagcaca aacgcaatcc agtggttcca ttcaaggaca aaccggctgg ctaacatgcc
     2161 cattccccag ccgatcagcg gcgtcagggt ttcgacggca ccaaaaataa ggccggttcg
     2221 caacgcttca gaaaatttcg gtttatggag ggtggcacct ttaccgattg atgcagcaaa
     2281 tgcatccatc gacataccaa acgcaagaag aacagtagca gtgatattca tgacaacgtc
     2341 ctgaccgggg tatccataaa acacatcatc gcccccagca aacatgcata catgaacaac
     2401 aagccgcgat gggttttcgc gttcatgcag gcatagcgat tgatgtgcat atggtctcgc
     2461 ctgactgaaa gtgttcagtc cgtacgtgcc acgttttgca acgagtatgt tgacacgtac
     2521 atttccggaa tctggaaatc ggctactccc caaatgaggg cgcaacctta acatattttg
     2581 agaatataaa acaactgttg gaatatatta tttcattgct ttattgataa cgattttcat
     2641 ttagatttat atatcaatga aacgttaaaa taaataa
//
LOCUS       DADXDL010000224         2668 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.227, whole genome shotgun sequence.
ACCESSION   DADXDL010000224 DADXDL010000000
VERSION     DADXDL010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2668
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.227"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            224..823
                     /locus_tag="IRB70_004900"
     CDS             224..823
                     /locus_tag="IRB70_004900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0634695.1"
                     /translation="MAKAKVLIDDTEEAIIKNALDVDDMNEVNINVTRKKKTGFLGTY
                     SIVFHDSVKTLSKMNLKPNAYKIVMYLFGIIEMGNILVNFSQKKIADDLGLQPSNVSR
                     AFKELFDKKVLIKDSEDGHVYLNSNLCTMGVPKNFDQKRMKSLQKSNIETEDFKNQIN
                     LFSPTNTTKIKTNDKKVIKKKEKENVLEFPMQNDWVDIE"
     gene            1553..2344
                     /locus_tag="IRB70_004901"
     CDS             1553..2344
                     /locus_tag="IRB70_004901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019704625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mobilization protein"
                     /protein_id="HBC0634696.1"
                     /translation="MLHDGKLAVSKLAKEDKKKLHQTVYTEAMIKFQDDFYTKVSNKF
                     GLSRTGEEPRERYKSRPEYLRFKKRQETALNILSDIEEFEADIKEKARKTGYSKGAKQ
                     FQNKTWVIKVGEAIKLLGKEHKAELDQKEKELEKIKKEKTEIETELNLKKEELSNAYS
                     QRNEASRKNSVYIDKVNALKKENKLLLPYKDQFDLKLQQEKEPLQAEVNSLTSENTNL
                     KNENSELKKENLDFKEFILGVKDYYGSKFDEWCKEIFKTKTKYKY"
BASE COUNT         1100 a          356 c          472 g          740 t
ORIGIN      
        1 aaaaaaaaaa ttatgaaaat cataattttc aattatgaaa atcataatgc aaaattatga
       61 aaatcataat cggacttatg aaaatcataa ttttacatac aagtgcattg ataagatttg
      121 atgttgaaat gataactttc ttatcgtttt gatattgaca ttgcatttag atcggttata
      181 aatgcaacat aggttattat ttttactaca aaaggaatat aaaatggcaa aagcaaaagt
      241 tttaatagac gatacagaag aagcaataat aaaaaatgca ttagatgttg atgatatgaa
      301 tgaagtaaat attaacgtca cgagaaaaaa gaaaactgga tttttaggga cttattcaat
      361 agtttttcat gattctgtaa aaacactctc taaaatgaat ttaaagccta atgcttacaa
      421 aatagttatg tatctttttg gcataataga gatgggtaat attttagtta acttctcaca
      481 gaaaaagatt gctgatgatc taggtttgca gccttcaaac gtatcaagag ctttcaaaga
      541 actttttgat aaaaaagttt taatcaaaga tagcgaagac ggacacgttt acttaaattc
      601 aaacttgtgc actatgggtg ttccgaaaaa ttttgatcaa aagagaatga aaagtttaca
      661 aaaatcaaat attgaaactg aagattttaa aaatcagatc aatttattta gtcctacaaa
      721 cacaacaaaa ataaaaacta atgataagaa agttatcaag aaaaaagaaa aagaaaacgt
      781 tttagagttt cctatgcaaa atgattgggt tgatattgaa tagtaaaact aatactaccg
      841 cacttcgttt gctgaatccc tgaagcccgc aaatataaaa tttgcaggct tcagggattt
      901 gctttttggt tttgaagttg actttaaccc cgtagggccg catctatgga gcagcatatg
      961 aaatatgcta gcgtaataga tatagtcggt tcctataact attgacagaa aaattatagg
     1021 tgttaattaa aaataaggaa acgaaaaaaa tataggagaa tataaaatga aatcacaatt
     1081 tatgcatgta gaactctaca gcagagaaga accagctaaa aagacaataa ataaaagtaa
     1141 aaatataaat cataaatctg atgttagaac aacaaccgta aacggtgtgt tgtcagaaat
     1201 gaaaagagag gaaggtttta catcacattt agagagcata catgcacctg atgtgctgta
     1261 cggctctata agcgatctag aacgctctat agagcgttac gaggctgaat ttaagactac
     1321 tgataaaaac ggcaaggaga agaagctacg caaagatgca tgcatcttgc tagctggtgt
     1381 agtttctcta gatcgagcag atgaagaaat ttgggatgaa tacaagaaat catctattga
     1441 atatttgaaa aataaatatg gtgaaaattt aaaatgtgtt gttgagcata cagacgaaac
     1501 aaacccacat ttccactttt atgtggtcgg taatcaaaaa caggatttaa atttgcttca
     1561 tgatggaaag ctcgcagtat ctaaattagc aaaagaagat aagaaaaaat tacatcaaac
     1621 agtctacaca gaagctatga tcaaatttca agatgatttt tatacaaagg tgtctaataa
     1681 atttggattg agcagaacgg gcgaggagcc gcgagaacgc tataaatccc gcccggaata
     1741 tttgagattt aaaaaaaggc aggaaacagc attaaatata ttatctgata tagaagaatt
     1801 tgaagctgat attaaagaaa aggcaaggaa aacgggatat agtaaaggtg caaaacaatt
     1861 tcaaaataaa acatgggtaa ttaaagttgg tgaagcaatt aaattacttg gaaaagagca
     1921 taaagcagaa ttagaccaaa aagaaaaaga gttagaaaaa ataaaaaaag aaaaaacaga
     1981 aattgaaact gagcttaatt taaaaaaaga agaattatct aatgcatata gtcaaagaaa
     2041 tgaagcatcg agaaaaaaca gcgtttatat tgataaagta aacgctctaa aaaaagaaaa
     2101 taaattatta cttccataca aagatcaatt tgatttgaaa ttacagcagg aaaaagagcc
     2161 attacaagca gaagtcaact ctttgacttc tgaaaatacc aatttgaaaa atgagaattc
     2221 agaactgaaa aaagaaaatt tagatttcaa agaatttatt ttgggtgtta aagattatta
     2281 tggatctaaa tttgatgaat ggtgtaaaga aatattcaaa acaaagacaa aatacaaata
     2341 ttaatctgaa atatattcat atctgccgcc tatgtggtgt atgagacacc accagaagcg
     2401 gcctgacagc gtttagctgt catagctggg atttatccca aaaaaagtag tttgcacgca
     2461 gttagtaacc tttaaatatc aataacttat aaagaaaaaa tacttaaacc gtgaaccgtg
     2521 aaaactgcag aacctctggt tctgtggttt gagcggttgt ccaacgaccc gaaggggagg
     2581 cggtaaggca gttgaagtta cggtttcttc tttcttattt tcttacttct taagcaccct
     2641 ttaaagcctt atatatcaac actttacc
//
LOCUS       DADXDL010000225         2595 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.229, whole genome shotgun sequence.
ACCESSION   DADXDL010000225 DADXDL010000000
VERSION     DADXDL010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2595
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.229"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1047)
                     /locus_tag="IRB70_004902"
     CDS             complement(join(<1..789,789..1047))
                     /locus_tag="IRB70_004902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611153.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBC0634697.1"
                     /translation="MTRRPRRNHSPAFKAKVALAAIRGEQTLVELSQQFDVHANQIKQ
                     WKDQLLEGATGVFGDETKAEPSGPTIDVKTLHAKIGELTLENGFFIRCARQGGIAGRK
                     EMIDREHKLSVVRQAKLLGFSRGSVYYLPRPVSDGDLALMRRIDELHLDYPFAGSRML
                     QGLLRGEGLETGRRHVATLMKKMGIKAIYRRPNTSKPAPGHIRKLAVTRPNQVWAMDL
                     TYIPMARGFVYLCAVVDWFSRKVLSWRLSITMEAAFCIEAVEEALARHGRPEIFNTDQ
                     GSQFTSIDFTAVLKRSQIAISMDGKGAWRDNVFVERLWRSIKYEEVYLHAYKTVSEAR
                     AGIARYLNFYNTRRP"
     gene            complement(1139..1681)
                     /locus_tag="IRB70_004903"
     CDS             complement(1139..1681)
                     /locus_tag="IRB70_004903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBC0634698.1"
                     /translation="MIIWINGPFGAGKTTLAERLRDRRPKSLIFDPEEIGFVVKETVP
                     IPASGDYQDLPLWRGLTIAAVSEIRRNYSQDIIIPMTLVHPDYLTEILDGLRQIDDQL
                     LHIFLMLNEDLLRHRISNQTMHPDPNRNAEIREWRLANVARCLAARERLPSTTRVLDS
                     GAHTSDELAAMVLDRLDQRT"
     gene            complement(1694..2554)
                     /gene="aac(3)-IIe"
                     /locus_tag="IRB70_004904"
     CDS             complement(1694..2554)
                     /gene="aac(3)-IIe"
                     /locus_tag="IRB70_004904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(3)-IIe"
                     /protein_id="HBC0634699.1"
                     /translation="MHTRKAITEAIRKLGVQTGDLLMVHASLKAIGPVEGGAETVVAA
                     LRSAVGPTGTVMGYASWDRSPYEETLNGARLDDKARRTWPPFDPATAGTYRGFGLLNQ
                     FLVQAPGARRSAHPDASMVAVGPLAETLTEPHELGHALGEGSPVERFVRLGGKALLLG
                     APLNSVTALHYAEAVADIPNKRWVTYEMPMLGRNGEVAWKTASEYDSNGILDCFAIEG
                     KPDAVETIANAYVKLGRHREGVVGFAQCYLFDAQDIVTFGVTYLEKHFGATPIVPAHE
                     AAQRSCEPSG"
BASE COUNT          513 a          795 c          718 g          569 t
ORIGIN      
        1 gtgggcgtct ggtgttgtag aagttcagat atcgggcgat gccagcgcgt gcctcggaca
       61 cagtcttgta ggcatggagg tagacttcct cgtatttgat cgaacgccag agccgctcga
      121 cgaagacatt gtctcgccac gcacccttgc catccatcga gatggcaatc tgtgacctct
      181 tcagcacggc ggtgaagtcg atggaggtga actgcgatcc ctggtcggta ttgaagattt
      241 ccggcctgcc atgacgggca agtgcctcct ccaccgcctc gatgcagaag gctgcttcca
      301 tcgtgatcga caaccgccat gacaagacct tccggctgaa ccagtccacg acggcgcaca
      361 gatagacaaa tccccgcgcc atggggatgt aggtcaggtc cattgcccac acctgattgg
      421 gccgggtgac tgccagcttt cgtatgtgcc ctggcgctgg tttcgaggtg ttcgggcggc
      481 ggtagatcgc cttgatgccc atcttcttca tcagcgtggc gacgtgtcgc cgcccggtct
      541 ccagaccttc tcctctcaag agcccttgca acatccgact tccggcaaag gggtagtcga
      601 gatgcaattc gtcaatccgg cgcataaggg ccagatcgcc gtcagacacc ggacgaggca
      661 gatagtagac gctgccacgg ctgaagccga gaagcttcgc ctggcgcacg acggatagct
      721 tgtgctcgcg gtcgatcatt tctttccgcc cagcaatccc gccttgccga gcgcaccgga
      781 taaaaaatcg ttctccagtg tcagttcgcc gattttcgcg tgcagcgttt tgacatcgat
      841 ggtcggaccc gacggctccg ctttcgtttc atcgccgaac acacctgtcg ccccctcaag
      901 gagctggtct ttccattgct tgatctggtt ggcgtgcaca tcgaactgct gggacaactc
      961 caccagcgtc tgctcacctc ggatggcggc aagtgccacc ttcgccttga aagccgggct
     1021 atggttccgg cgcggtcgtc tcgtcatggt ctctcctgtt cccggcatct aagccgaagt
     1081 caggcagaaa ctccacttat ccccgctgtg cagatttccc gagccagctc taaggcgatc
     1141 aggtgcgctg atcgagtctg tcgagcacca tcgctgcaag ttcatcgctg gtgtgtgcac
     1201 cactatcgag aacacgggtt gtggacggaa gccgttccct tgcggccaag catcgggcga
     1261 cattcgctaa tcgccactct cgaatctccg cattccgatt cgggtcagga tgcatggtct
     1321 ggttcgagat ccggtgacgc aataggtcct cgttaagcat cagaaagatg tgcagcagct
     1381 gatcgtcgat ctgccttaac ccgtcgagta tctcagtcag atagtccggg tgcacgagcg
     1441 tcattgggat gatgatgtcc tgcgagtaat tcctgcgaat ctcgctgacc gcagcgatcg
     1501 taagtcccct ccacaagggg agatcctgat agtctccgct cgctggtatg gggaccgttt
     1561 ctttcaccac gaacccgatt tcctcagggt caaagatcag cgatttcgga cgccgatcgc
     1621 gcagccgctc agcgagagtc gtctttccgg cgccgaaagg tccgttgatc cagattatca
     1681 ttgtcgacgg cctctaaccg gaaggctcgc aagagcgctg ggcggcttcg tgtgctggca
     1741 cgatcggagt ggctccgaag tgcttctcaa gataggtgac gccgaacgtc acgatgtcct
     1801 gcgcgtcgaa caggtagcac tgagcaaagc ccacgacacc ttctcgatgg cgaccgagct
     1861 tcacgtaagc atttgctata gtttcgaccg catccggctt tccttcgata gcaaagcaat
     1921 cgagaatgcc gtttgaatcg tattctgatg ccgttttcca ggcgacttca ccgtttcttc
     1981 caagcatcgg catctcatac gtcacccatc gtttgttggg gatatccgca accgcctcgg
     2041 cgtagtgcaa tgcggtaacg gagtttagcg gcgcacccaa cagcagggcc ttcccgccaa
     2101 ggcggacgaa ccgctcgacg ggcgaccctt cccccaaggc gtgaccgagt tcgtgaggct
     2161 ccgtcagcgt ttcagctagc ggaccaaccg cgaccatcga tgcatcgggg tgcgcgctgc
     2221 gccgcgcgcc gggggcttga accagaaatt gattcagcag gccgaaccca cggtaagtcc
     2281 cggccgttgc gggatcgaac ggcggccagg tacggcgggc tttgtcatcc aaccgagcgc
     2341 cattcagagt ctcctcgtag ggtgatcggt cccacgacgc gtatcccatc acagtgccag
     2401 tcggcccaac cgcggagcgt aacgcggcaa cgaccgtctc cgctcctcct tcgaccggac
     2461 caatcgcttt aagtgaggca tgcaccatca acaggtcacc ggtttggact cctaattttc
     2521 gaattgcctc cgttattgcc ttccgcgtat gcatcgcgat atctcctcta aactgcaaaa
     2581 cactatacct atcga
//
LOCUS       DADXDL010000226         2577 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.230, whole genome shotgun sequence.
ACCESSION   DADXDL010000226 DADXDL010000000
VERSION     DADXDL010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2577
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.230"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..745
                     /locus_tag="IRB70_004905"
     CDS             <1..745
                     /locus_tag="IRB70_004905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416772.1"
                     /note="ElaD; specific cysteine protease which targets
                     ubiquitin and ubiquitin-like proteins covalently bound to
                     target proteins; SseL in Salmonella is required for
                     macrophage killing and virulence, and it is secreted by
                     the salmonella pathogenicity island 2 type III secretion
                     system; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="deubiquitinase"
                     /protein_id="HBC0634700.1"
                     /translation="TNFWDKNRQLTTDEIDCYLQKIAASAKNTQVNYPTGLYLPDSNS
                     TYLEIALNDNIKSDPSWPKEVQLFPINTGGHWILVSLQKIVNEKNNTQQIKCVIFNSL
                     RALGHDNENSLKRIINSFNSELIGEMSNNNIKVHLTEPEIIFLHADLQQYLSQSCGAF
                     VCMAAQEVIEQRESNSDSAPYTLLKNYADRFKKYSAEEQYEIDFQHRQANRNCYLDKY
                     GDANINHYYRNLEIKYSHPQNKASGKRVS"
     gene            complement(816..>2577)
                     /locus_tag="IRB70_004906"
     CDS             complement(816..>2577)
                     /locus_tag="IRB70_004906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBC0634701.1"
                     /translation="NKNIIMLLMSSLILSGCGPESENKESLQQQPSTPTDQQVLAAQH
                     AAIKEAEQRSVAAKATADAKAKALAQQEAQQYSDKQALQGRLQAAPKYQHAAREKAAS
                     QIANPGTARYQQFDDNPVKQVAQNPLATFSLDVDTGSYANVRRFLNHGQLPPPDAVRV
                     EEMVNYFPSDWVINDKSNNKEPVPASKPIPFAMRYELAPAPWNEQRTLLKVDILAKDR
                     KSEELPASNLVFLIDTSGSMISYERLPLIQSSLKLLVKELREQDNIAIVTYAGDSRIA
                     LPSISGSHKAEINAAIDSLDADGSTNGGAGLELAYQQAAKGFIKGGINRILLATDGDF
                     NVGIDDPKSIESMVKKQRESGVSLSTFGVGDSNYNEAMMVRIADVGNGNYSYIDTLAE
                     AQKVLNSEMRQTLISVAKDVKAQIEFNPAWVTEYRQIGYEKRQLRAEDFNNDNVDAGD
                     IGAGKHITLLFELTLKGQKASIDKLRYAPDNKSAKSDKTKELAWLKIRWKYPQGKESQ
                     LVEFPLGPTINAPSEDMRFRAAVAAYGQKLRGSEYLDEISWQQIKQWAQQAKGEDQQG
                     YRAEFIRLVELAGGVTDISQ"
BASE COUNT          719 a          606 c          516 g          736 t
ORIGIN      
        1 gacaaacttc tgggataaaa atcgtcaatt aaccacggat gaaatagatt gctatcttca
       61 gaagatcgcc gctagtgcaa aaaatactca agtcaattat cctactggtc tctacctccc
      121 cgattccaac agcacttacc tggaaatcgc tctcaatgat aatattaaga gcgatccatc
      181 atggccgaaa gaagtccagt tattccccat aaatactggc ggacactgga tattagtttc
      241 gctacaaaaa atagttaatg aaaaaaataa cacacaacaa ataaaatgcg tcatattcaa
      301 ctcattacgt gcactaggcc atgataacga aaattcactt aagcgtatca ttaatagttt
      361 taattctgaa ctcataggag aaatgtcgaa taataatata aaagttcatt taactgaacc
      421 cgagataata tttttacatg ccgatcttca gcaatattta agccaaagtt gcggtgcatt
      481 tgtgtgcatg gcagcccagg aagtgattga acaaagggaa agcaattctg acagcgctcc
      541 ctatacgtta ttaaaaaact atgctgacag atttaaaaaa tattcagcag aagagcagta
      601 cgaaattgat tttcaacatc gacaggcaaa cagaaattgt tatttagata aatatggcga
      661 tgcaaatatc aatcattatt atagaaactt agaaataaaa tattcacacc cccaaaataa
      721 agcatcagga aaaagagtaa gttaacatca ttgttaatta attcgaccag tcagtaaata
      781 tgctgactgg tcgaacatag tttgctaaaa agtcatcact gactgatgtc agtcacacca
      841 cccgccagtt caaccaggcg aataaattcc gccctgtaac cctgttgatc ttcccctttt
      901 gcctgctgag cccactgttt tatctgctgc catgagattt cgtccaggta ttcagaaccg
      961 cgtaactttt gcccatatgc agctactgct gcgcgaaaac gcatatcttc agagggcgcg
     1021 tttattgttg gccccagcgg gaattcaact aactgacttt cttttccctg cgggtatttc
     1081 caacgaatct ttaaccaggc aagttctttt gttttgtccg atttcgctga tttgttatcc
     1141 ggggcatagc gtaacttatc aattgatgct ttttgccctt tcagcgttaa ttcgaataac
     1201 aacgttatat gtttacctgc gccaatatca cccgcatcaa cgttgtcgtt attaaaatct
     1261 tccgcccgaa gttggcgctt ttcataacca atctgacggt attccgttac ccacgcgggg
     1321 ttaaactcaa tttgcgcttt gacatctttt gctacgctaa tcaacgtctg ccgcatttca
     1381 ctgttcaata ctttctgtgc ttcagcgagg gtatcaatgt agctgtagtt accgttgcca
     1441 acatcggcga ttcgcaccat cattgcctcg ttgtaattgc tatcccccac gccaaacgtg
     1501 gacagagaaa caccggactc ccgctgtttt ttgaccattg attcaatcga tttaggatcg
     1561 tcaatgccga cgttaaaatc accatcagtg gccaataaaa tgcgattgat gccaccctta
     1621 ataaacccct tcgccgcctg ctgataagcc agttccagcc cggcaccgcc attggtactg
     1681 ccatcggcat ccagcgaatc aattgcggca ttaatttccg ccttgtgact cccggagata
     1741 gaaggcaacg caatacggga gtcgccagcg taggtcacga tggcaatgtt atcctgctca
     1801 cgaagttctt tgaccaataa tttcaacgaa gactggataa gaggcaaacg ttcataagaa
     1861 atcattgaac cagaagtgtc gataagaaag accagattag aagctggtaa ctcttcactt
     1921 ttgcgatctt tcgccaggat atcaactttc agcaatgttc gctgttcatt ccacggcgca
     1981 ggtgccagtt cgtagcgcat agcgaaaggt attggcttac tggcgggaac aggttcttta
     2041 ttattgcttt tatcattaat aacccagtct gacggaaaat aattcaccat ctcctccacc
     2101 cgcactgcat ctggcggagg caactgccca tgattgagaa aacggcgtac attcgcataa
     2161 ctgccggtgt cgacgtcaag gctaaatgtc gccaacgggt tttgcgctac ctgcttaacc
     2221 ggattatcat cgaactgctg atagcgagcg gttcctggat ttgcgatttg ggaggctgct
     2281 ttttctctgg ctgcatgttg atattttgga gccgcctgta agcgcccctg caaagcctgt
     2341 ttgtctgaat attgttgcgc ttcttgctgg gctaaggctt ttgctttcgc gtctgcagtg
     2401 gctttagcgg cgacggatct ttgctcggcc tcttttattg cagcatgttg cgcggcaagc
     2461 acttgctggt ctgtgggagt actgggttgt tgttgcagac tttccttatt ctcagattcc
     2521 ggcccacatc ctgacaaaat caaactactc ataagcaaca tgattatatt tttattt
//
LOCUS       DADXDL010000227         2554 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.231, whole genome shotgun sequence.
ACCESSION   DADXDL010000227 DADXDL010000000
VERSION     DADXDL010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2554
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.231"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            182..625
                     /locus_tag="IRB70_004907"
     CDS             182..625
                     /locus_tag="IRB70_004907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001074369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634702.1"
                     /translation="MAKIYEFPQGAERSKLKKEIIRERKKRLRETNGNPVIRHAKWFW
                     FYLRLATAGALHLVSVISLAVLGAFSKAIFWIGGMLCVVTWFHLERQFWTPQNFTIPV
                     IVTLWGLSLFATPLMELLNKKMPWYRLLVPDAKHTSTEATNDDQP"
     gene            744..818
                     /locus_tag="IRB70_004908"
                     /pseudo
     CDS             744..818
                     /locus_tag="IRB70_004908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000202958.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
     gene            813..1358
                     /locus_tag="IRB70_004909"
     CDS             813..1358
                     /locus_tag="IRB70_004909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000757693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA distortion polypeptide 1"
                     /protein_id="HBC0634703.1"
                     /translation="MKKVQFRIEESQHDDLLDCLKTLYPDEPGLTVAKGMKLLANALL
                     KSKVKNEDVNVSKDNDDFIKTTMYLTGKQRTLIEKAAHRHGWNLSRECRYRIQTTLEN
                     ELDFFDQELLVMNRCRNAIDKIGRNFHYIIVNDNARVLDKDGFYQDAERLSSEIMSLK
                     SEFENYIMLCKGRTVSNKVEV"
     gene            1361..2521
                     /locus_tag="IRB70_004910"
     CDS             1361..2521
                     /locus_tag="IRB70_004910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001549912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBC0634704.1"
                     /translation="MGVYVDKEFRVKRKSSEAGRKSAFAHKVKNGGKNYQRNVQERIN
                     RKGASKEVVVKISGGAITRQGVRNSIDYMSRESELPVMSESGQVWKGDEIQEAKEHMI
                     DRANDPQNVFDDKGKENKKVTQNIVFSPPVSAKVKPEDLLESVRKTMNKKYPNHRFVL
                     GYHNDKKEHLHVHVVFRIRDNDGKRADIRKKDLREIRTGFCEELKMKGYDVKATHKQQ
                     HGLNQSIKDAHKTAPKRQKGVYEVVDVGYDHYQNDKTKPKQHFIKLKTLNKGVEKTYW
                     GADFGELTTRENVKKGDLVKLKKLGQKEVKIPALDKNGVQHGWKTAHRNEWQLENLGV
                     KGIDRISSSSKELVLNSAEMIKKQQLQMRNFSQIKQSMIQSEQKVKIGIRLG"
BASE COUNT          823 a          455 c          621 g          655 t
ORIGIN      
        1 agaaaacgga aataaatcag ttatctttct ctgttgttgg gaaaaaaggg agaatggctc
       61 acatgcttag atttgagttt agtataaatg aaaaatcctc atccttttcg gaagatgata
      121 tggcattttt agaggagttt gacaaagtcg ttccaccaaa aaagaataag tgaggcaaaa
      181 catggctaaa atatatgagt ttccgcaggg agccgaacga agtaagctga aaaaagaaat
      241 catccgggaa cgtaaaaaac gattgcgaga aacgaacggt aacccggtta tccggcacgc
      301 taaatggttc tggttttatc tacgtcttgc tacggctggc gcactgcatt tagtctctgt
      361 tatttctctg gcagtcctgg gggctttcag taaagctatt ttctggattg gtggaatgct
      421 ctgtgttgtt acatggttcc accttgagcg ccagttctgg acgccgcaaa atttcacgat
      481 tccagtaatc gtaacgctgt ggggattgag tttgtttgcc actcccctga tggagctgct
      541 taacaaaaaa atgccgtggt atcgtcttct ggttcctgat gcaaagcaca ctagcactga
      601 ggcaaccaat gatgatcagc cgtgaagcaa caatgttatc cagtcggctt gcagtgcttc
      661 tttcagcctt ttatcatcgg ttaatcatag cgcacgaggc gagttctttt cactgcgatg
      721 caggataggg caaacgccgc aaaatgacgt ctctgacgcc attccgcaac gtttgcccgg
      781 tgacctacag tcggttcttg ttggagagtt ttatgaaaaa agttcaattc aggattgaag
      841 aaagccaaca tgatgatcta cttgattgtc ttaaaacact ttatccagat gaaccgggtt
      901 taaccgtggc aaaaggaatg aagctgcttg ccaatgcttt actgaaaagc aaggttaaaa
      961 atgaagatgt taatgtgtca aaagacaatg atgattttat caaaaccaca atgtatttga
     1021 cagggaaaca aagaacttta atagagaaag cggctcatcg tcatggctgg aatttatcca
     1081 gagaatgtcg ttatcgaatc cagacgacac ttgaaaatga acttgatttt ttcgatcagg
     1141 aacttctggt gatgaatcgt tgccgtaatg caatagataa aatagggcga aactttcatt
     1201 atattatcgt taatgataat gccagagtac ttgataaaga tgggttctat caggacgctg
     1261 agcggttgag ttcagagata atgagtctca aaagtgagtt tgaaaactac attatgttat
     1321 gcaaagggcg aactgtttct aacaaggttg aggtgtaatc atgggcgttt atgttgacaa
     1381 ggaattcagg gttaagcgta agtcctctga agctggccgc aagtctgctt tcgcccataa
     1441 agttaaaaat ggtggtaaaa actatcaacg caacgttcag gaacgtatca accgcaaggg
     1501 tgccagtaag gaggttgttg tcaaaatctc aggaggtgcg attacccggc agggagttcg
     1561 aaacagtatt gactatatga gccgggagtc agagctgcca gtgatgagtg aaagcggtca
     1621 ggtatggaaa ggtgatgaga ttcaggaggc taaagagcac atgatagatc gtgctaatga
     1681 ccctcaaaat gttttcgatg ataaaggtaa ggaaaataaa aaagtaaccc aaaatattgt
     1741 gttttcaccg cctgtatcag caaaggtaaa acctgaagat ctgcttgagt ctgtcaggaa
     1801 aacgatgaac aagaagtacc caaatcatcg ttttgtgctt ggctatcata acgacaaaaa
     1861 agaacatcta cacgtgcatg tcgtttttcg tattcgtgat aatgacggta aacgagctga
     1921 tatcaggaaa aaagatttac gggaaattcg tacaggtttt tgtgaagagc tgaagatgaa
     1981 gggctatgac gttaaagcca ctcataagca gcagcatgga cttaaccagt ctattaaaga
     2041 tgcgcacaaa acagcgccaa aacgacagaa gggcgtttat gaggttgttg atgttggcta
     2101 cgaccattat cagaacgata aaaccaaacc aaagcagcat ttcataaagc ttaagacact
     2161 gaacaagggc gtggagaaaa catattgggg ggctgatttt ggtgagttaa ccactcgcga
     2221 gaacgttaag aaaggtgatc ttgttaagct gaagaagtta ggacaaaagg aggtgaaaat
     2281 ccctgcactt gataagaacg gtgtacagca tggctggaag actgcacaca ggaatgagtg
     2341 gcagctagag aacctggggg ttaagggcat agacagaatc tcttcatcca gtaaagagct
     2401 ggtgctgaac agcgcggaga tgattaagaa acagcaactc cagatgagaa atttctcgca
     2461 aataaaacag tcgatgattc aaagcgaaca gaaagtgaaa atcggaattc gtttaggata
     2521 attcatactc tccggtaact tattgattaa gatc
//
LOCUS       DADXDL010000228         2411 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.232, whole genome shotgun sequence.
ACCESSION   DADXDL010000228 DADXDL010000000
VERSION     DADXDL010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2411)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2411)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2411
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.232"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..488
                     /locus_tag="IRB70_004911"
     CDS             <1..488
                     /locus_tag="IRB70_004911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBC0634705.1"
                     /translation="TDTLEIFNNSDEWASQLKHALSQGENLALLHGLTPDILDRIYAY
                     AFDYHEKGNITDAEIYYKFLCIYAFENHEYLKGFASVCQSKKKYQQAYDLYKLSYNYS
                     PYDDYSVIYRMGQCQIGAKNIDNAMQCFYHIINNCEDESVKSKAQAYIELLTDNSEDN
                     G"
     gene            823..2199
                     /gene="ygeH"
                     /locus_tag="IRB70_004912"
     CDS             823..2199
                     /gene="ygeH"
                     /locus_tag="IRB70_004912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HilA family transcriptional regulator YgeH"
                     /protein_id="HBC0634706.1"
                     /translation="MDLENKFSYHFLEGLTLTEDGILTQGNEQIYIPPKELGVLIVLL
                     ESAGHVVLKDMIIESVWKNIIVSDESLTRCIYSLRCIFEKIGYDRCIETIYRKGYRFS
                     GQVFKTKINEDNTSDYSIAIFPFTTSLNTLDPLILNQELVQNISDKKFDGLYTYPMAA
                     TNFCNDHITQNSFLRRFKPDYFVTGRINQNNAVKTLYIELIDAKNLFLIASNHLPVDE
                     LHNTSQFIIDNILQTVHNPERSVRLAKPNQGYKNHYLSDELLAGKKELYEFTPESIYR
                     AMAIFDGLQNKSDIQTLKIECYCLLAECHMSLALHGKYELELAAQKALELLHYVSDIT
                     NVDGKILAIMGLITGLSGQAKVSHILFEQAKIHTTDIASLYYYRALVNFHNERIEEAR
                     ICIDKSLQLEPRRRKAVVIKECVDMYVPNPLKSNMKLYYKETSSESHRVIIDNILKLK
                     QLTRICMR"
BASE COUNT          878 a          399 c          404 g          730 t
ORIGIN      
        1 gcacagatac acttgaaata ttcaataaca gtgatgaatg ggcaagtcaa ctaaaacacg
       61 cattatcgca aggagaaaat ctggcattac tacatggatt gactcctgat atccttgata
      121 gaatatatgc atatgcattc gactaccatg aaaaaggtaa tataacggac gcagaaattt
      181 attataaatt tctgtgcatt tatgcgttcg aaaatcatga atatctaaaa ggttttgcat
      241 cagtatgcca gtcaaaaaag aaatatcaac aagcatatga cctttacaaa ctaagttaca
      301 attactcccc gtatgatgac tattcagtta tttatcgtat gggtcaatgt caaattgggg
      361 ctaaaaatat cgataacgca atgcaatgtt tctatcatat tattaacaat tgtgaggatg
      421 aaagtgttaa gagcaaagcg caggcatata ttgaactctt aaccgataat tcagaagata
      481 atggctaagc attacaagca tttggttaaa attgctggtt atagtgcagt taaccactat
      541 gaccagcttc tcttatgttt tcttaaatca acatcttaaa acagttaaga acacactata
      601 aattactatt tttcaacgcg ttagagaaca atctatttta tcaaaattga ataagactat
      661 ttcagattac atcactgaat tcctaagata aattagtgaa cacaaccata gatatgtcga
      721 atgtaaactc ctgtagcatt aatgacacat aaatatgaat agccacaatt tctattgctt
      781 atgcaggatg caagaaacca attttttcat agaggttaac taatggactt agaaaataaa
      841 ttctcatatc attttcttga gggattaacg ctcacggaag atggaattct tactcaagga
      901 aatgagcaga tttatattcc accgaaagag ttaggagtat tgatcgtatt acttgaatcc
      961 gctggtcatg ttgtcctgaa agatatgatc atcgaatcag tatggaaaaa tattattgta
     1021 agtgacgagt ccctgacaag atgtatctat tctttgcgct gcatttttga aaaaattggc
     1081 tatgatcgtt gcatagaaac aatctaccgg aaaggttatc gtttcagtgg acaggttttc
     1141 aaaactaaaa taaatgaaga taacacttca gactattcca tagctatatt tcctttcacc
     1201 acttcattga ataccctgga tccattaata cttaatcagg aattagtgca aaacatttcg
     1261 gataaaaaat tcgatggcct ttatacctat ccgatggctg cgacaaattt ttgtaatgat
     1321 cacataacgc aaaattcatt tttgagaaga ttcaagccag attatttcgt tacaggaaga
     1381 ataaaccaga ataacgcggt gaaaacttta tacattgaac tgatcgacgc taaaaatctt
     1441 ttcctcatcg ccagtaatca tcttcctgtt gatgaactac ataacacatc acaatttatt
     1501 atagataata tccttcaaac ggtacataat ccagagcgtt ctgtaagatt agctaaaccg
     1561 aaccaaggtt acaagaatca ttatttatca gatgaactgt tggctggtaa gaaagaactt
     1621 tacgagttta ctcctgaaag catttacagg gctatggcta tatttgatgg attacaaaat
     1681 aaaagtgata tacagacgct aaaaatagaa tgttattgtc tgctagcgga atgccatatg
     1741 tctttggcac ttcatggaaa gtatgaactt gaacttgctg ctcaaaaagc attagagctt
     1801 ttacattatg tatcagacat aaccaatgtc gatggaaaaa ttttagctat tatgggactg
     1861 ataactggtt tgtctggaca agcaaaagta tctcatatct tatttgaaca ggctaagata
     1921 cacacaactg atatagcctc tctctactac tatagagcac ttgtcaattt tcataatgaa
     1981 agaattgaag aggcaaggat ttgtatagac aaatcactac aactcgaacc cagaagacga
     2041 aaagcagttg tgataaaaga gtgtgtagat atgtatgtgc ctaacccgct caaaagcaac
     2101 atgaaactct actataaaga aacttcgagt gaaagccatc gagtgataat tgacaacatt
     2161 ttgaaactaa agcaactaac gagaatttgt atgcgataaa tctttattgt cgcaatttta
     2221 ttgtttagat gtatgcaact ggttatgtaa acaacagaga tgaaaacatc taagataatt
     2281 accttattgc aatatatatc aaatactcta gattaaaaag tattgtgtat aggctattgg
     2341 cctggacaaa taaaaaaggg aactttatga ctaatccaat caatatgaat aatttttctc
     2401 aaagtttaaa t
//
LOCUS       DADXDL010000229         2409 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.233, whole genome shotgun sequence.
ACCESSION   DADXDL010000229 DADXDL010000000
VERSION     DADXDL010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2409)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2409)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2409
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.233"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..370
                     /locus_tag="IRB70_004913"
     CDS             <1..370
                     /locus_tag="IRB70_004913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634707.1"
                     /translation="MGFSPRLCRPFRAQTKGKVERMVQYTRNSFYIPLMTRLRPMGIT
                     VDVETANRHGLRWLHDVANQRKHETIQARPCDRWLEEQQSMLALPPEKKEYDVHLDEN
                     LVNFDKHPLHHPLSIYDSFC"
     gene            379..825
                     /gene="istB"
                     /locus_tag="IRB70_004914"
                     /pseudo
     CDS             379..825
                     /gene="istB"
                     /locus_tag="IRB70_004914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858162.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
     gene            907..1311
                     /locus_tag="IRB70_004915"
     CDS             907..1311
                     /locus_tag="IRB70_004915"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBC0634708.1"
                     /translation="MKSLTAVRKKSPNYPVEFKIKMVELSHRPEISVAQLAREHGIND
                     NLLFKWRQYWREGKLRPPSTTENNVPELLPITLDAEDVVPTTSPRSQPVAAATPESLN
                     ISCEVTFRHGSLRLNGAISENILNLLIRELKR"
     gene            1308..1655
                     /gene="tnpB"
                     /locus_tag="IRB70_004916"
     CDS             1308..1655
                     /gene="tnpB"
                     /locus_tag="IRB70_004916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004966400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBC0634709.1"
                     /translation="MIPLPSGTKIWLVAGITDMRNGFNGLAAKVQTTLKDDPMSGHVF
                     IFRGRNGSQVKLLWSTGDGLCLLTKRLERGRFAWPSARDGKVFLTPAQLAMLLEGIDW
                     RQPKRLLTSLTML"
     gene            1704..>2409
                     /locus_tag="IRB70_004917"
     CDS             1704..>2409
                     /locus_tag="IRB70_004917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66-like element ISEc22 family transposase"
                     /protein_id="HBC0634710.1"
                     /translation="MSSSLPDDINALKRLLAEQEALNRALQEKLNEREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLKALQKESDTLTGRVDDPAVQRPLRQTRTRKPF
                     PESLPRDEKRLLPAASCCPECGGSLSYLGEDAAEQLELMRSAFRVIRTVREKHACTQC
                     DAIVQAPAPSRPIERGIAGPGLLARVLISKYAEHTPLYRQSEMYGRQGVELSRSLLSG
                     WVDACCRLLSPLEEALQ"
BASE COUNT          594 a          677 c          646 g          492 t
ORIGIN      
        1 gatgggcttc tctccccgac tgtgtcgccc cttcagggca cagactaaag gtaaggtgga
       61 acggatggtg cagtacaccc gtaacagttt ttacatccca ctaatgactc gcctgcgccc
      121 gatggggatc actgtcgatg ttgaaacagc caaccgccac ggtctgcgct ggctgcacga
      181 tgtcgctaac caacgaaagc atgaaacaat ccaggcacgt ccctgcgatc gctggctcga
      241 agagcagcag tccatgctgg cactgcctcc ggagaaaaaa gagtatgacg tgcatcttga
      301 tgaaaatctg gtgaacttcg acaaacaccc cctgcatcat ccactctcca tctacgactc
      361 attctgctga ggagtggcgt gatgatggaa ctgcaacatc aacgactgat ggcgctcgcc
      421 gggcagttgc aactggaaag ccttataagc gcagcgcctg cgctgtcaca acaggcagta
      481 gaccaggaat ggagttatat ggacttcctg gagcatctgc ttcatgaaga aaaactggca
      541 cgtcatcaac gtaaacaggc gatgtatacc cgaatggcag ccttcccggc ggtgaaaacg
      601 ttcgaagagt atgacttcac attcgccacc ggagcaccgc agaagcaact ccagtcgtta
      661 cgctcactca gcttcataga acgtaatgaa aatatcgtat tactggggcc atcaggtgtg
      721 gggaaaaccc atcttgcaat agcgatgggc tatgaagcag tccgtgcagg tatcaaagtt
      781 cgcttcacaa cagcagcaga tctgttactt cagttatcta cggcagtaag cgtcgtctca
      841 gcaccgtctg gcagatcctg aaattcctga gagaatagtg gacaccaaat atggtggacg
      901 ctatccatga aatcattaac cgcagtgcgt aaaaaaagcc ctaattatcc cgttgagttc
      961 aaaatcaaaa tggttgaact ctcgcatcga ccagagatct ccgtagcgca actcgctcgt
     1021 gagcatggga tcaacgataa tttgctgttc aagtggcgcc agtactggcg cgaaggaaaa
     1081 ctacgtcctc cttcaacaac agaaaacaac gtgcctgagc tgctcccgat aacacttgat
     1141 gccgaagatg ttgtccctac aacctccccc cggtcacaac ctgtagctgc tgcgacacct
     1201 gaatcactca atatcagctg tgaagtgacg ttccggcacg gatcactccg tctgaatggt
     1261 gccatcagcg aaaatatcct gaacctgctg atacgggagc tcaaacgttg atcccattac
     1321 catcagggac aaagatctgg ctggtcgctg gcatcaccga tatgagaaac ggcttcaacg
     1381 gcctggcggc aaaggtgcag acgacgctga aagacgatcc gatgtcaggt cacgttttta
     1441 tcttccgtgg gcgtaatggc agtcaggtaa agctcctctg gtctaccggc gatggactgt
     1501 gtctgctgac caaacggctg gagcgcggcc gcttcgcctg gccgtcagcc cgggatggca
     1561 aagtgttcct cacaccggca cagctggcga tgctgctgga aggtatcgac tggcggcagc
     1621 ctaaaagact acttacgtcc ctgactatgt tgtaagcctc tttatcctgg tcgacgctga
     1681 atgagcctgg taatataccc ggtatgagca gctcacttcc tgacgatatc aatgcactga
     1741 aacgtctcct tgccgaacag gaggcgctga accgtgccct gcaggaaaag ctgaacgagc
     1801 gtgaacgcga aatagaccat ctgcaggcac agctggataa gctgcgccgg atgaacttcg
     1861 gcagccgctc ggaaaaagtc tcccgtcgta tcgcacagat ggaagctgac ctgaaggcac
     1921 ttcagaaaga aagtgatacc cttaccggtc gggttgacga cccggccgtg cagcgcccgc
     1981 tgcgtcaaac ccgcacccgc aaaccgttcc ccgaatcact cccccgcgat gaaaaacggc
     2041 tgctgccggc agcgtcatgc tgcccggaat gtggaggctc gctgagctat ctgggtgagg
     2101 atgccgccga acagctggag ttgatgcgca gcgccttccg ggttatccgg actgtacgtg
     2161 aaaagcatgc ctgtactcag tgcgatgcca tcgtgcaggc ccccgcgcct tcacggccca
     2221 tcgagcgggg tatcgcagga ccggggctgc tggcccgcgt gctgatctca aagtatgcag
     2281 agcacacccc gctgtaccgc cagtctgaaa tgtacggccg ccagggcgtg gagctgagtc
     2341 gttcactgct gtcgggctgg gtggatgcat gctgccggct actgtcaccg ctggaagaag
     2401 cgcttcagg
//
LOCUS       DADXDL010000230         2404 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.234, whole genome shotgun sequence.
ACCESSION   DADXDL010000230 DADXDL010000000
VERSION     DADXDL010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2404
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.234"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..616
                     /locus_tag="IRB70_004918"
     CDS             <1..616
                     /locus_tag="IRB70_004918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="capsule assembly Wzi family protein"
                     /protein_id="HBC0634711.1"
                     /translation="GFTGHDNTGTDNEPGNQLAGFDFKFKLEPTLGWPVSFYGQMIGE
                     DESGYLPSANMYLGGVEGHHSWGKDAVNWYLEAHDTRTNMSRTNYSYTHHIYKDGYYQ
                     QGYPLGDAMGGDGQLVAGKVELITEDNQRWSTRLVYAKVNPENQSINKAFPHADTLKG
                     VQLGWSGDVYQSVRLNTSLWYTNANNSDSDDVGASAGIEIPFSL"
     gene            762..1895
                     /locus_tag="IRB70_004919"
     CDS             762..1895
                     /locus_tag="IRB70_004919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide export protein"
                     /protein_id="HBC0634712.1"
                     /translation="MKKKIVRFSALALAIGFLSGCTVIPGQGLNSLRKNVVELPDSDY
                     DLDKLVNVYPMTPGLIDQLRPETVLARPNPQLDNLLRSYEYRIGVGDVLMVTVWDHPE
                     LTTPAGQYRSASDTGNWVNSDGTIFYPYIGKVQVAGKTLSQVRQDIASRLTTYIESPQ
                     VDVSVAAFRSQKAYVTGEVAKSGQQPITNIPLTVMDAINNAGGLAPDADWRNVVLTHN
                     GKDTKVSLYALMQKGDLTQNHLLYPGDILFVPRNDDLKVFVMGEVGKQSTLKMDRSGM
                     TVAEALGNAEGMSQAFSDATGIFVIRQLKDDKQGKIANIYQLNAQDASAMVLGTEFQL
                     QPYDIVYVTTAPLVRWNRVISQLVPTITGVHDMTETGKFIRTW"
     gene            1901..2341
                     /locus_tag="IRB70_004920"
     CDS             1901..2341
                     /locus_tag="IRB70_004920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775086.1"
                     /note="Wzb shows phosphatase activity towards the
                     autophosphorylated Wzc protein, which induces colanic acid
                     biosynthesis; catalyzes the phosphorylation of UDP-glucose
                     dehydrogenase, an enzyme involved in colanic acid
                     biosynthesis; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein tyrosine phosphatase"
                     /protein_id="HBC0634713.1"
                     /translation="MFNSILVVCTGNICRSPLGERYLRAALPEKKIDSAGTGALVGYQ
                     ADPTAIKIALEHDISLEGHIAKQFTSTMSRHYDLILVMEKYHIEKIGRIAPEARGKTM
                     LFGHWLKQREIPDPYKKSEEAFASVYQLIEQAGMRWVDKLSGSY"
BASE COUNT          697 a          477 c          601 g          629 t
ORIGIN      
        1 tggcttcact ggccatgaca ataccggaac ggataacgaa cctggtaacc agctggccgg
       61 atttgacttt aagtttaaac tcgagccaac tctcggctgg ccggtgagct tctacggaca
      121 gatgatcggc gaagatgagt caggttatct gccttcggcc aatatgtatc tgggcggtgt
      181 ggaaggccac cacagctggg gtaaggatgc tgttaactgg tacctggaag cacatgacac
      241 gcgcaccaat atgagccgaa ccaattacag ttatacgcat catatctata aggatggcta
      301 ctatcagcag ggttatccgc tgggtgacgc aatgggcggg gatggtcaac tcgttgccgg
      361 taaagttgag cttattacgg aggataacca gcgctggagc acgcgtttag tatacgcgaa
      421 ggttaacccg gagaatcagt cgatcaacaa agcgttccct catgcggata ctctaaaagg
      481 tgtacagctg ggctggagcg gcgatgttta tcagtcggtc cgcttgaata cttcactgtg
      541 gtacaccaac gctaacaaca gcgacagcga tgacgttggg gccagcgcag ggatagagat
      601 accatttagt ttataaggct gaatgctgaa aacaggggag agtaggtggt agcgctgcag
      661 gacgcagtca gcttttctct cttcataagc cggcagggaa gcaacggcga tgacagctgc
      721 tcaggaattg gcaaattttg atttactgat gatgtgacat tatgaagaaa aaaattgtta
      781 gattttcggc attagcattg gcgattggtt ttttatcggg ttgtacggtt atcccaggcc
      841 aagggttaaa tagtctgcgg aagaacgtgg ttgagcttcc tgatagcgac tacgatctgg
      901 acaaactggt gaacgtgtat ccgatgactc caggactgat cgatcagctc cgtccggaaa
      961 ccgttcttgc tcgtccaaat ccccagttag ataatttact gcgcagttat gaatatcgca
     1021 ttggagttgg cgatgtgttg atggttacgg tatgggacca cccggaactg acgactcctg
     1081 caggtcaata ccgtagcgcc agcgacaccg gtaactgggt taactctgac ggtaccatct
     1141 tctatcctta tatcggtaaa gtacaggtgg cagggaaaac acttagccag gtacgccagg
     1201 atattgccag ccgtttgaca acatacatcg aaagtccaca ggttgacgtt agtgttgcag
     1261 cattccgttc gcaaaaagcc tatgtgactg gcgaggtagc aaaatcagga cagcagccaa
     1321 ttactaatat cccccttacg gttatggatg ccattaataa tgctggtgga ctggctcctg
     1381 atgccgactg gcggaatgtt gtgttaacac ataatggtaa agacacaaaa gtctctttat
     1441 atgcattaat gcagaaaggt gacttgactc aaaatcactt actttatccc ggcgatatcc
     1501 tttttgtacc acgtaatgat gatctaaaag tatttgtcat gggtgaggtg ggcaaacaaa
     1561 gtactttaaa aatggaccgt agtggtatga cggtagctga agctttaggt aatgccgaag
     1621 gaatgtctca agcattcagt gacgcaacag gaatatttgt cattcgtcag ttaaaagatg
     1681 ataagcaggg taaaattgct aatatttatc agctcaacgc ccaagacgct tctgctatgg
     1741 tacttggtac agaattccag ttacagccat acgatatagt atatgtcaca actgctcctt
     1801 tggtacgttg gaatcgtgtc atctcgcagc ttgtaccgac tataactggc gtgcatgata
     1861 tgacagaaac tgggaaattc ataaggactt ggtaataact atgtttaatt caatccttgt
     1921 tgtttgtacc ggtaatattt gtcgctcacc attaggcgaa agatatttaa gagcagcctt
     1981 gcctgaaaaa aaaatagatt ctgctggaac aggggcatta gttggttatc aggcagatcc
     2041 aacagcaatt aaaattgctt tagagcatga tatatcgctc gaaggacata tagccaaaca
     2101 atttacttcc acaatgtcta gacattacga tttgatttta gtaatggaga aatatcatat
     2161 agaaaaaata ggtcgaatag ctcctgaagc tagaggcaaa acaatgctgt tcggtcattg
     2221 gttaaaacaa agggaaattc ctgacccgta caaaaaaagt gaggaagcgt ttgcttcagt
     2281 ttatcagtta attgagcaag ccggcatgcg ttgggttgat aaattaagcg gcagttatta
     2341 ggaataatta tatggcatct attactaata agaatgaaat aaagggctcg ggtgaactgg
     2401 attt
//
LOCUS       DADXDL010000231         2333 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.235, whole genome shotgun sequence.
ACCESSION   DADXDL010000231 DADXDL010000000
VERSION     DADXDL010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2333)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2333)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2333
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.235"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            103..342
                     /locus_tag="IRB70_004921"
     CDS             103..342
                     /locus_tag="IRB70_004921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311745.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system needle complex
                     protein"
                     /protein_id="HBC0634714.1"
                     /translation="MADWNGYIMDISKQFDQGVDDLNQQVEKALEDLATNPSDPKFLA
                     EYQSALAEYTLYRNAQSNVVKAYKDLDSAIIQNFR"
     gene            362..694
                     /gene="sctI"
                     /locus_tag="IRB70_004922"
     CDS             362..694
                     /gene="sctI"
                     /locus_tag="IRB70_004922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system inner rod subunit
                     SctI"
                     /protein_id="HBC0634715.1"
                     /translation="MSVSNMPPIDRAEQSAAHEIQQAKVIDLNDRVLNLDNPDDKMIS
                     AFANYAVQTENWQQNALQALRSDKKGLTPEKLLVLQDHVLNYNVEVSLVGTLARKIVA
                     AVETLTRS"
     gene            691..1425
                     /locus_tag="IRB70_004923"
     CDS             691..1425
                     /locus_tag="IRB70_004923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscJ/YscJ/HrcJ family type III secretion inner
                     membrane ring protein"
                     /protein_id="HBC0634716.1"
                     /translation="MKYISLFLFILLLCGCKQQELLNHLDQQQANDVLAVLQRHNINA
                     EKKDQGKIGFSIYVEPTDFASAVDWLKIYNLPGKPDIQISQMFPADALVSSPRAEKAR
                     LYSAIEQRLEQSLKIMDGIVSSRVHVSYDVDTGDSGKTALPIHISVLAVYEKDINPEI
                     KINDIKRFIVNSFASVQYENISVVLSKRRDIIEQAPTYEINEPIFAYDKTMPVSILLA
                     LMSIATCWLLWKYRAILTNLIRLKNK"
     gene            1441..2022
                     /locus_tag="IRB70_004924"
     CDS             1441..2022
                     /locus_tag="IRB70_004924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion apparatus protein OrgA/MxiK"
                     /protein_id="HBC0634717.1"
                     /translation="MNLALRKIIYDPISYIHPQRVSWNNARISNPVLRSITNEMILLQ
                     YNLSVEHFSLNSSLIYYINNWKLFPLICLLSGCHFYRERFAERGFFYKVPDVLRNYLS
                     AIPVEINEKARYKPGIVNYQNIITCGFSTLLPYVRQQPLAMQQRFNLLFPDFVDHIQL
                     PLPVASTLLERITFYAKKNRDELDKLSCKWCCD"
     gene            1964..>2333
                     /locus_tag="IRB70_004925"
     CDS             1964..>2333
                     /locus_tag="IRB70_004925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019842356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634718.1"
                     /translation="MRKKIEMSLINSPANGVVIKRIISDGLKEIVSLKEQILLETTAK
                     IQSIEEKREEKIIQGYYDGYAKGIIDVMDNFIPLISLLSSELEKNRVNMINDLKSILL
                     KSSEEVEVFIKIFESWVTKLP"
BASE COUNT          787 a          372 c          457 g          717 t
ORIGIN      
        1 aaaatcagga cacaaataac agttcattta gctacggaga taatcgattc gagaagtctc
       61 aaggtagcaa gtggacattt caggaataat tgaggaggac ttatggcaga ttggaatggt
      121 tatattatgg atatcagcaa acaatttgat cagggggttg atgatctgaa ccagcaagtt
      181 gaaaaagcgt tggaggattt agcaaccaat ccttccgacc cgaaattcct tgccgaatat
      241 cagagtgcat tagctgagta tacattatat cgaaatgcgc aatctaacgt tgtaaaagcg
      301 tataaagatc ttgattcggc aatcatacaa aacttccgct aaactggata aggattttat
      361 tatgtcagta agcaatatgc cacctattga tagagctgag caatcagctg ctcatgaaat
      421 acagcaagcg aaagttattg atttaaatga ccgggttctc aatcttgata acccggatga
      481 taaaatgatc tccgcttttg ctaactatgc ggtacaaact gaaaattggc agcaaaatgc
      541 gttacaagca ttaaggtctg ataaaaaggg gttaactcct gaaaaattat tagtcttgca
      601 ggatcatgtg cttaattata atgtcgaggt ttcattggtg ggaacattag caagaaaaat
      661 tgtcgctgca gttgagacgt tgactcgctc atgaaatata tatcattatt cttgtttatc
      721 ctgctgttgt gcggttgcaa gcagcaggaa ttactgaacc atcttgatca acagcaagct
      781 aatgatgtcc ttgctgtttt acaaagacat aatattaatg ctgagaagaa ggatcaaggc
      841 aaaattggat tttcaatcta tgtagaacca acggattttg cttctgcggt ggattggcta
      901 aaaatctaca atctcccggg taagcctgat attcaaatat cgcagatgtt tcctgcagat
      961 gcactcgttt cctctccacg agcggaaaaa gcaagattgt attctgctat tgaacagcgt
     1021 ttggagcaat ctctcaaaat tatggatggc attgtttctt caagagtaca tgttagttac
     1081 gatgttgata caggtgatag tggcaaaact gctttaccaa ttcatatttc tgtacttgct
     1141 gtatatgaaa aagatatcaa tccagaaata aaaataaatg acattaaaag atttattgtt
     1201 aatagctttg caagcgtaca atatgagaat atttcagtcg tattgtcaaa acgaagagat
     1261 attattgaac aagcaccaac atatgaaatt aacgaaccta tttttgctta tgataagact
     1321 atgccggttt ctatcttact tgcattaatg tccattgcga cttgctggct gttatggaag
     1381 tacagggcta ttctaactaa tttaatcagg ttaaaaaata agtagacata tgagaacgtt
     1441 atgaatcttg ccctaagaaa gattatatat gatccaatta gttatattca tcctcaacga
     1501 gtaagttgga ataatgcacg tattagcaat ccggtactta gatctattac caatgaaatg
     1561 atactcctac agtacaatct ttcagttgag cattttagtc tgaatagttc acttatttac
     1621 tacataaaca attggaaatt atttccattg atctgtttac tcagtggttg tcacttttat
     1681 cgagaaaggt ttgcagaacg cggatttttt tacaaggttc ctgatgtgct aaggaattat
     1741 ttatcagcga taccggtgga aataaatgaa aaggcacgat ataaacctgg catcgttaac
     1801 tatcagaata tcatcacatg tggtttttca acgttgttgc cctatgtaag gcaacaaccg
     1861 ttggcaatgc agcaacgatt taatttatta tttcctgatt ttgttgacca catacaattg
     1921 ccgttaccag ttgcgtctac tcttttggag agaattacat tttatgcgaa aaaaaataga
     1981 gatgagcttg ataaactctc ctgcaaatgg tgttgtgatt aaaagaataa tttctgatgg
     2041 attgaaagaa atagtttctc taaaagaaca gatccttctt gaaaccaccg caaaaattca
     2101 gagtattgag gaaaagagag aagaaaaaat tattcaaggt tattatgatg gctatgcgaa
     2161 aggcattatt gatgtgatgg ataattttat acccttgata agtttgctga gctcagaatt
     2221 agaaaaaaac agagtaaaca tgataaacga tctgaagagc atattgttaa aatcttcaga
     2281 ggaagttgaa gtttttatca aaatttttga aagttgggta acaaaattac cgt
//
LOCUS       DADXDL010000232         2284 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.236, whole genome shotgun sequence.
ACCESSION   DADXDL010000232 DADXDL010000000
VERSION     DADXDL010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2284)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2284)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2284
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.236"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1371)
                     /locus_tag="IRB70_004926"
     CDS             complement(<1..1371)
                     /locus_tag="IRB70_004926"
                     /inference="COORDINATES: protein motif:HMM:NF015210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF262 domain-containing protein"
                     /protein_id="HBC0634719.1"
                     /translation="MNFDATPLNIKNILSVKQRYVIPRNQREFSWEKLQLEELWQDIV
                     RNIRLNEDGQNLECSEYFIGTIVLSGADSDDVLEVVDGQQRFSVITILLSLISRKLRS
                     LGQDSLADDIFKTYIVTVSPTFSRSQLASNGETFIEKLAKNSDRTYFKLKYQDREEHQ
                     VDESCEEDVRISYAGIFLSRKLGRKSLCSALLRDGAKHYNNQDYIFCLTAVYRMITNY
                     LKLVKISVGKEDDAYDIFEVLNARGINLSSIDLIKNKVFQTCTQTYPVDIAKTKWDYI
                     VTQIESRDSNSTIADYIRTWWLSKYNYIGEDQLYRAFKREIQDENTLLSSASFLNELY
                     DDVELYCKIIAPNTDDWPQPDQREIYNSLKAFEIFNVSIPRPFVLSLLRKRKEKPRAL
                     TQSMLIECLKSLESFHFKFNAVCRLRPSGIDAKYSVLAVRMNKALNKRDVEGVINDAL
                     DYFTQKV"
     gene            1905..>2284
                     /locus_tag="IRB70_004927"
     CDS             1905..>2284
                     /locus_tag="IRB70_004927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000883169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634720.1"
                     /translation="MLDARKNIDLIKDIDEISEKGIQAFGLLYDESGHSNLHDPLLRW
                     CDFLLRYIAPQKRIILKSDRFPENIHDGARVGLQRIEMLFTTGGDVNPYQSKTLTLFN
                     DTSGKKATKRTDNLWADWGIHHLHL"
BASE COUNT          757 a          438 c          357 g          732 t
ORIGIN      
        1 tactttctgt gtaaaataat ctaacgcgtc attaataaca ccctcaacat ctcttttatt
       61 taatgcctta ttcattctta ctgctaatac agaatatttt gcatcgattc cagatggtct
      121 tagacgacat actgcattaa acttaaagtg aaatgactct aaggacttca aacattctat
      181 cagcattgat tgtgtaaggg ctctcggttt ctctttacgt tttctaagta atgagagtac
      241 aaatggtcga ggaatactca cattaaaaat ctcgaatgct tttaacgagt tgtaaatttc
      301 acgctgatca ggttgaggcc agtcatctgt atttggcgct attattttac agtataattc
      361 aacatcatca tataattcgt tcagaaatga tgctgatgac aataaagtat tctcatcttg
      421 aatctcacgt ttaaaagcac gataaagttg atcttctcca atataattat acttagaaag
      481 ccaccacgtt ctaatataat cagcaatagt gctattacta tccctagact caatttgagt
      541 aacgatataa tcccattttg tttttgcaat atctaccgga tatgtttgag tgcaagtttg
      601 gaatacttta ttctttatca aatcaattga acttaagttt atccctcgag cattcaacac
      661 ttcaaaaata tcataagcat catcctcctt acctacagat atttttacca acttcaaata
      721 attggtaatc attctatata cagcagtcaa acaaaatata taatcttggt tattataatg
      781 ttttgcacca tctcgcaaca atgcagaaca gagtgatttc ctccctagtt ttctagaaag
      841 aaaaattcct gcataactta tacgtacatc ctcttcacaa gattcatcaa cttgatgctc
      901 ttcgcgatct tgatatttta acttaaaata tgttctatcg ctattttttg ctaatttttc
      961 aataaatgtc tcaccatttg aagctaattg gcttctgcta aatgtaggac tcacagtaac
     1021 gatatatgtt ttaaatatat catccgctaa tgaatcttgc cctaaggaac gcaatttacg
     1081 cgatattaat gaaagcaata tagtaataac tgaaaatcgt tgttgtccat caaccacttc
     1141 taatacatca tcactatctg ctccagaaag aacaatagtc cctataaaat attctgaaca
     1201 ctccaagttc tgtccatctt cattcaacct tatgtttctg acaatatctt gccataactc
     1261 ttcaagctga agcttttccc aactaaactc acgttgatta cgaggaataa catatctttg
     1321 ttttacagat agaatgtttt ttatatttag tggtgttgca tcaaaattca taacttatcc
     1381 tcagagacaa caaattgata ataatgtcct attcaaatgg ctaatgatat gacataaaaa
     1441 aagaaaaatg caatgtacta caagaatatc agtaaacgtt tctagcgcgc gctcgtatcc
     1501 ccgccacgcc tgcccacttt atgcagtggt tttcatgcag ctgcatgaca tgagcaaaag
     1561 cccgccattt ctggctggtc taagcataga cgatcctcga tcgatcatgc gatttcatgc
     1621 agcatagtta tgcactgcca tgggaagtta acgtatctga ataatcgctt gaaaaacgaa
     1681 catatgggct tgcaaagatg aaagcccgct tgagcgaaaa gtggaaaatc aacatgttac
     1741 aaagcttgaa aattactttt gttcttgaaa aatcagccca accattacta tagtattatc
     1801 taaattggtt aatgtgccct gaaatcaccg gaaaattcag ctataacggc gtatagatat
     1861 taattaactg aaatactaaa aaattatatt taaacggagt tagtatgttg gacgcacgaa
     1921 aaaatattga tctaatcaaa gatattgacg aaatttcaga gaagggaatt caagcatttg
     1981 ggttattata tgatgaatcc gggcactcaa atcttcacga tcctctactg aggtggtgtg
     2041 attttctttt acgctacatt gctccacaaa aacgaataat tttaaaatca gatcgatttc
     2101 ctgaaaatat tcacgatggc gcaagggttg gattgcagag aatcgagatg ttgtttacta
     2161 ctggtggtga tgtaaatcct tatcagagta aaacattaac attattcaat gacacaagcg
     2221 gtaaaaaggc gacgaaaaga acggataacc tatgggctga ttgggggatt catcacctcc
     2281 atct
//
LOCUS       DADXDL010000233         2274 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.237, whole genome shotgun sequence.
ACCESSION   DADXDL010000233 DADXDL010000000
VERSION     DADXDL010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2274)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2274)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2274
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.237"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..708)
                     /locus_tag="IRB70_004928"
     CDS             complement(<1..708)
                     /locus_tag="IRB70_004928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000364797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBC0634721.1"
                     /translation="MDLLAESITEVAVSGEIANTDRVLNIAYGIDRNFLFGAAVSMQS
                     VVMHNPDLAVKFHLFTDYIDEDYLQRVNAFTSKNANVEVRIYKVSSAFIDIFPSLKQW
                     SYATFFRLVAFQYLSETIENLLYIDADVICKGSLAGLLDINFDGDKFAAVIKDVPFMQ
                     EKPAKRLAIEGLPGNYFNAGVVYLQLEAWAKNDFMNKAIAMLASDPQHTKYKCLDQDI
                     LNILFFGHCIFISGDYDC"
     gene            complement(734..1426)
                     /gene="rfaY"
                     /locus_tag="IRB70_004929"
     CDS             complement(734..1426)
                     /gene="rfaY"
                     /locus_tag="IRB70_004929"
                     /EC_number="2.7.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000633080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipopolysaccharide core heptose(II) kinase RfaY"
                     /protein_id="HBC0634722.1"
                     /translation="MITSIRYRGFSFYYKDNDNKYKEIFDEILAYNFKTVKVLRNIDD
                     TKVSLIDTKYGRYVFKVFAPKTKRNERFLKSFVKGDYYQNLIVETDRVRSAGLTFPND
                     FYFLAERKIFNYASVFIMLIEYVEGVELNDMPIIPENVKAEIKASMEKLHALNMLSGD
                     PHRGNFIVSKDGVRIIDLSGKSCTAERKARDRLAMERHLGIVNEIKDYGYYSVIYRTK
                     LRKFIKKLKGKA"
     gene            complement(1436..>2274)
                     /locus_tag="IRB70_004930"
     CDS             complement(1436..>2274)
                     /locus_tag="IRB70_004930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001001722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="lipopolysaccharide 1,2-glucosyltransferase"
                     /protein_id="HBC0634723.1"
                     /translation="VFHVFTDYVDDDYLKSFNETAKQFNTSIIVYLIDPKYFADLPTS
                     QFWSYATYFRVLSFEYLSESISTLLYLDADVVCKGSLKPLTKIIFKDEFAAVIPDNDS
                     TQAACAKRLNIPEMNGRYFNAGVIYVNLKKWHEANLTPYLLTLLRGETKYGSLKYLDQ
                     DALNIAFNMNNIYLAKDFDTIYTLKNELHDRSHRKYQQTITDKTVLIHYTGITKPWHS
                     WAGYPSASYFNIAREQSPWKKYPLKEARTVAEMQKQYKHLFAHGEYIKGITSLIKYKL
                     KK"
BASE COUNT          719 a          444 c          394 g          717 t
ORIGIN      
        1 gcaatcataa tcgccgctaa taaaaataca atgaccaaag aacagaatat ttaaaatatc
       61 ctgatcaagg catttatact tcgtgtgctg cgggtcactt gccagcatag caatggcttt
      121 attcataaaa tcatttttcg cccatgcttc aagctgcaga tatactacac cggcgttgaa
      181 ataattccct ggaagtccct ctatagccag acgcttcgct ggtttttcct gcataaaagg
      241 cacatcttta ataacagctg cgaacttatc gccatcaaaa ttaatatcaa gcaatccagc
      301 taatgagcct ttacagatga catcagcatc gatatataac agattttcaa tagtttcact
      361 cagatactgg aacgcaacta aacggaagaa tgttgcataa gaccactgtt tcaggctggg
      421 gaagatatca ataaaggcac tggagacttt ataaattctt acttcaacgt tagcattttt
      481 gctggtaaaa gcattaacac gttgtagata atcttcatca atgtagtcag taaagagatg
      541 aaacttaacc gcaaggtccg ggttatgcat aacaactgat tgcatagata ctgccgcacc
      601 aaataaaaag ttgcggtcaa taccgtaagc gatatttaac acacgatcgg tgttagcaat
      661 ttccccagag acagcgactt cagtaatact ctcagctaat aaatccatgt tggttccgtt
      721 ttgactgtgt ggtttacgct ttgcctttta attttttaat aaatttgcgt agtttggttc
      781 tgtagattac tgaatagtag ccataatctt ttatttcgtt gacaataccc aggtgacgtt
      841 ccatggccag acgatcacga gctttacgct ctgccgtaca gcttttaccg gataggtcaa
      901 ttatcctgac accatcttta ctaacgataa agttaccccg gtgtgggtcg cccgatagca
      961 tatttaaggc atgcaatttt tccattgaag ccttaatttc tgctttaaca ttttctggaa
     1021 taatcggcat atcattgagc tctacgccct cgacatactc gataagcatg ataaaaacac
     1081 tggcatagtt gaaaatttta cgctcagcca gaaaataaaa atcattagga aaagtaagac
     1141 ctgcacttct gacacgatcg gtttcaacga tcaaattctg atagtagtca ccttttacaa
     1201 aagattttaa aaaacgttca ttccttttcg ttttcggagc aaagacttta aaaacatagc
     1261 gaccatattt cgtatcaatc aacgatactt tggtatcatc aatattacgt aatactttta
     1321 ctgttttaaa attataggcc agtatttcat caaagatttc tttatattta ttatcattat
     1381 ctttgtaata aaatgagaag ccgcgataac gtatacttgt aatcataaga gtaatttatt
     1441 tcttaagctt gtacttaatt aatgaagtta tgccttttat atactcacca tgggcaaaca
     1501 gatgcttata ttgtttctgc atttctgcaa cagtccgcgc ctctttaaga ggatatttct
     1561 tccagggaga ttgttcacgc gcgatattaa agtatgatgc agacggatat ccagcccagc
     1621 tatgccatgg tttagttatc cctgtatagt gaatcaatac tgttttatct gtaatggttt
     1681 gctgatactt tcgatgacta cgatcatgaa gttcgttttt cagggtataa atagtatcaa
     1741 aatccttcgc gaggtagata ttattcatat taaatgcgat attcaacgca tcctgatcta
     1801 aatatttaag agagccatat ttagtttccc ctcgtaaaag cgtgagtaaa tacggtgtca
     1861 aatttgcttc atgccatttt ttaagattga catagataac gcctgcattg aaataacgtc
     1921 cattcatttc gggaatgtta agacgttttg cacatgccgc ctgagtacta tcattgtcag
     1981 gaataaccgc agcaaactca tctttaaata taatttttgt gagaggtttc agacttcctt
     2041 tacaaacgac atcggcatcc agatacagca gtgtggaaat actttcactc agatattcaa
     2101 aggacaatac cctgaagtat gtcgcgtacg accaaaactg tgacgtcggc agatcagcaa
     2161 agtatttggg gtcaattaaa tatacaataa ttgaggtatt aaattgtttt gctgtttcat
     2221 taaatgactt taaataatca tcatccacat aatcagtgaa aacatgaaag acaa
//
LOCUS       DADXDL010000234         2268 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.238, whole genome shotgun sequence.
ACCESSION   DADXDL010000234 DADXDL010000000
VERSION     DADXDL010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2268
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.238"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1..613
                     /gene="virK"
                     /locus_tag="IRB70_004931"
                     /pseudo
     CDS             1..613
                     /gene="virK"
                     /locus_tag="IRB70_004931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858370.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="virulence factor VirK"
     gene            678..1622
                     /gene="lpxM"
                     /locus_tag="IRB70_004932"
                     /gene_synonym="msbB"
     CDS             678..1622
                     /gene="lpxM"
                     /locus_tag="IRB70_004932"
                     /gene_synonym="msbB"
                     /EC_number="2.3.1.243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858371.1"
                     /note="LpxM is lauroyl-Kdo(2)-lipid IV(A)
                     myristoyltransferase, an enzyme characterized in
                     Escherichia coli and involved in biosynthesis of the form
                     of lipid A found in that species and some closely related
                     species; Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lauroyl-Kdo(2)-lipid IV(A) myristoyltransferase"
                     /protein_id="HBC0634724.1"
                     /translation="MKKYKSEFIPEFKKNYLSPVYWSTWFLLGMIAGISMFPPSFRDP
                     VLAKIGRWVGRLSKKARRRATINLSLCFPEKSDTEREIIVDKMFATALQSIVMMAELA
                     IRGPEKFQKRVFWKGLEILEEIRHNNRNVIFLVPHGWSVDIPAMLLAAQGKKMAAMFH
                     QQRNPVIDYVWNSVRRKFGGRLHAREDGIKPFIQSVRQGYWGYYLPDQDHGPEYSEFA
                     DFFATYKATLPIIGRLMNISQAMIIPLFPVYDEKKHLLTIEIRPPMDACIASADNKMI
                     ARQMNKTVEILVGPHPEQYVWVLKLLKTRKSNEADPYP"
     gene            1803..>2268
                     /locus_tag="IRB70_004933"
     CDS             1803..>2268
                     /locus_tag="IRB70_004933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634725.1"
                     /translation="MSRKTQRYSKEFKAEAVRTVLENQLSISEGASRLSLPEGTLGQW
                     VTAARKGLGTPGSRTVAELESEILQLRKALNEARLERDILNCTGVAEKYALIEQWRQQ
                     FPIEAMCQVFGVSRSGYYNWVQHEPSDRKQSDERLKLEIKVAHIRTRETYGTR"
BASE COUNT          685 a          446 c          528 g          609 t
ORIGIN      
        1 aaaaatcggt atcattagtc caattcatcg ggaaagatgg agagaatttt gatatccagt
       61 gttctcccag tggttttgac cgggaaggag agttgatgtt gtcattgttt tacaataaaa
      121 cagttattgc ccggttaaca ttttcagtca ttctgactca aaatggacac attgctttta
      181 ttggcggatt acagggagcc cctaaaaata ccggacctga tgttattcgg tgcgcaaccc
      241 gggcctgtta tgggattttc ccaaaacgga ttatttttga agcattttgt gcgttgatga
      301 aagcttgcaa tatctctgag tgtctggcag tcagtgagca cagtcatgtt ttccggcaat
      361 tgagatactg gtatcagaaa cgcaaaacct ttgttgcggt ctatagtgat ttctgggagt
      421 ctgtagcagg aaaaaccgtg gtgactggta cagattacca acccaggtga ttcgaaagcc
      481 gctaagcgat atagccagta aaaaacgctc tgagtaccga aaacgatacg ctttgctgga
      541 ttatatccat gaaactacta tccgctcttt ggatgcatat cctgtacact cagaacatca
      601 gaatttaaat taaggtttga tgtattctct gaataaaaca gtaatgataa ttttggtaga
      661 ggcattcgca ctaaataatg aaaaaatata aatctgagtt tattcctgaa tttaagaaaa
      721 attacctttc ccctgtttac tggtctacat ggttcctttt gggaatgatt gcaggtattt
      781 caatgtttcc cccttcattc agagatcctg tcttggcaaa aatagggcgt tgggtgggca
      841 gattgagcaa aaaagctcgt cgcagggcga cgattaattt atcgctttgt ttcccagaaa
      901 agagtgatac agaacgggaa ataattgtcg acaaaatgtt tgccacagca ttgcaatcca
      961 tagtgatgat ggcagaactg gcaattcgtg gtccggaaaa gttccagaaa cgagtgttct
     1021 ggaaaggcct cgaaattctt gaggaaattc gacacaataa tagaaatgtg atttttctgg
     1081 ttccccatgg ctggagcgtg gatattcctg caatgttgct ggcagctcag ggaaaaaaaa
     1141 tggccgccat gtttcatcag caacgaaatc cagtgattga ttatgtctgg aattcagtac
     1201 ggcgtaaatt cggggggcgc ttacatgccc gggaggatgg gataaaacca tttattcagt
     1261 cagtacgcca gggatactgg ggatattacc tcccagatca ggatcatggt cctgaataca
     1321 gtgaatttgc tgattttttt gcgacctata aagcgacatt accaatcatt ggacgtctga
     1381 tgaacatcag tcaggctatg attataccac ttttcccggt ttatgatgaa aaaaaacatc
     1441 tcctgactat tgaaattcgg ccaccaatgg atgcttgcat tgccagcgcg gacaataaaa
     1501 tgattgcccg acaaatgaac aaaacagtgg aaattttggt ggggccacat ccggaacagt
     1561 atgtctgggt tttaaaattg ttaaaaacac gcaaatcaaa cgaagcggac ccgtaccctt
     1621 gaaattataa agtacaagta tttccactag ttgtttgtaa gcgtacagcc tgaaccgtct
     1681 ggtcagaatc tgacgaatta gacaaagtgg tgtccaccaa ataagtagtg ggaaccaatg
     1741 aggtagcctg agtttaacgg acactccttc ctgaaataga atggcatcag aaggagctaa
     1801 taatgagcag aaaaacccaa cgttactcta aagagttcaa agccgaagct gtcagaacgg
     1861 ttcttgaaaa tcaactttcg atcagtgaag gtgcttcccg attatctctt cctgaaggca
     1921 ctttaggaca atgggttacc gccgccagaa aagggctcgg tactcctggt tcccgcacgg
     1981 tggctgaact ggaatctgaa attctgcaac tgcgtaaggc gttaaatgaa gctcgccttg
     2041 agcgagatat attaaattgc acaggagtcg ctgaaaaata cgcgttaatc gaacaatggc
     2101 gacaacaatt tcccattgaa gcgatgtgtc aggtatttgg tgtatccagg agcggttatt
     2161 acaactgggt acagcatgaa ccctcagaca gaaaacaaag tgatgagcgg ctaaaactgg
     2221 agattaaggt ggcgcatatc cgcactcgcg aaacatatgg aacccggc
//
LOCUS       DADXDL010000235         2244 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.241, whole genome shotgun sequence.
ACCESSION   DADXDL010000235 DADXDL010000000
VERSION     DADXDL010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2244
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.241"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            133..825
                     /locus_tag="IRB70_004934"
     CDS             133..825
                     /locus_tag="IRB70_004934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312724.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBC0634726.1"
                     /translation="MPLSAQQLAAQKNLSYVLAEKLAQRILKGEYEPGTILPGEIELG
                     EQFGVSRTAVREAVKTLTAKGMVLPRPRIGTRVMPQSNWNFLDQELLTWWMTEENFHQ
                     VIDHFLVMRICLEPQACLLAATVGTAEQKAHLNTLMAEMAALKENFRRERWIEVDMAW
                     HEHIYEMSANPFLTSFASLFHSVYHTYFTSITSDTVIKLDLHQAIVDAIIQSDGDAAF
                     KACQALLRSPDK"
     gene            848..>2244
                     /gene="mdtD"
                     /locus_tag="IRB70_004935"
     CDS             848..>2244
                     /gene="mdtD"
                     /locus_tag="IRB70_004935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug transporter subunit MdtD"
                     /protein_id="HBC0634727.1"
                     /translation="MSDKKKRSMAGLPWIAAMAFFMQALDATILNTALPAIAHSLNRS
                     PLAMQSAIISYTLTVAMLIPVSGWLADRFGTRRIFTLAVSLFTLGSLACALSNSLPQL
                     VVFRVIQGIGGAMMMPVARLALLRAYPRNELLPVLNFVAMPGLVGPILGPVLGGVLVT
                     WATWHWIFLINIPIGIAGLLYARKHMPNFTTARRRFDITGFLLFGLSLVLFSSGIELF
                     GEKIVASWIALTVIVTSIGLLLLYILHARRTPNPLISLDLFKTRTFSIGIVGNIATRL
                     GTGCVPFLMPLMLQVGFGYQAFIAGCMMAPTALGSIIAKSMVTQVLRRLGYRHTLVGI
                     TVIIGLMIAQFSLQSPAMAIWMLILPLFILGMAMSTQFTAMNTITLADLTDDNASSGN
                     SVLAVTQQLSISLGVAVSAAVLRVYEGMEGTTTVEQFHYTFITMGIITVASAAMFMLL
                     KTTDGNNLIKRQRKS"
BASE COUNT          536 a          542 c          552 g          614 t
ORIGIN      
        1 tctgaccgcg cattttttca gcaaaagccc cgttaatgtg ccataaaaca agcaatttgc
       61 cgtttttgca accgtaatca cacttcctgg tggcatacta aggaggaata aaaagaaaaa
      121 ggaagattag taatgccttt aagcgcacaa cagttagctg cacagaaaaa cctttcgtat
      181 gttctggctg agaagctggc gcaacgcatc ttaaaaggtg aatatgaacc cggcaccatt
      241 ttgcctggtg agattgagct gggcgagcaa tttggagtga gtcgtacagc ggtacgcgaa
      301 gcggtcaaaa cgttaacggc aaaagggatg gttttaccgc gaccgcgaat tggtacccgg
      361 gtcatgccac aatcaaactg gaattttctt gatcaggaat tgcttacctg gtggatgaca
      421 gaagagaact ttcatcaggt catcgatcac tttctggtta tgcgtatctg tctggagccg
      481 caagcttgcc tactggcagc aacggttggc accgcggaac agaaggcgca tctcaatacg
      541 ttaatggccg aaatggcggc attaaaagag aactttcgcc gtgaacgctg gatcgaagtc
      601 gatatggcct ggcatgagca tatctatgaa atgagcgcca atccgttttt gacctcattc
      661 gcctcgctat tccattcggt ttatcacact tacttcacgt caattaccag cgacacagtg
      721 ataaagctgg atctgcacca ggcgattgtt gacgcgatta tccaaagcga tggcgacgcg
      781 gcatttaaag cttgtcaggc gctgctacgc tcacctgata agtgacaccc cgataacagg
      841 acattgaatg agcgataaaa agaagcgcag tatggcgggt ttgccgtgga tcgcggcgat
      901 ggccttcttc atgcaggcac ttgatgccac tattctgaat accgccttac ccgcaatcgc
      961 tcatagcctt aatcgttctc ctctcgcgat gcaatcagcc atcatcagtt atacgctgac
     1021 ggtggcgatg cttattccgg taagcggatg gctagccgat cgcttcggta cgcgtcgcat
     1081 atttaccctt gccgtgagtc tgttcacgtt gggttctctg gcctgcgcac tttctaactc
     1141 gctaccacag ctggttgtct tccgggttat tcaggggata ggcggcgcaa tgatgatgcc
     1201 tgttgctcgg ctggccttac tgcgcgctta tcctcgtaat gagcttcttc ctgtattgaa
     1261 ttttgtcgcc atgccgggtc tggtggggcc aattttaggc cccgttcttg gcggcgtgct
     1321 ggtcacctgg gcaacctggc actggatatt tttaatcaat atccccatag gtattgcggg
     1381 ccttctttac gcgcgcaaac atatgcccaa tttcaccacc gcacgacgca gattcgatat
     1441 cactggcttt ttgctgtttg gccttagcct tgttctcttc tcaagcggaa tagagctatt
     1501 cggggaaaag attgtcgcca gttggattgc cttgacggta attgtcacca gcatcgggtt
     1561 actgcttctc tatattctcc atgcacgacg cacgccaaac ccattaattt cattagattt
     1621 atttaaaacc cgcactttct cgatcggtat cgtaggcaat attgcaaccc gtctggggac
     1681 cggttgtgta ccgttcctta tgccattgat gttacaggta ggatttggtt atcaggcgtt
     1741 tattgccggc tgtatgatgg caccgacagc gttaggttcc attattgcaa aatcgatggt
     1801 tacccaagtc ttacgtcgtc tgggctatcg ccatacgtta gtggggatca cggtgattat
     1861 tgggctaatg atcgctcagt tctctttgca atcaccagca atggcgatat ggatgctgat
     1921 cttgccgttg tttatattag ggatggctat gtcgacgcaa tttaccgcga tgaataccat
     1981 cacacttgcc gatctgaccg atgacaacgc cagcagcggt aacagtgttc tggcggtcac
     2041 gcagcaactg tctatcagtt taggcgttgc tgtaagtgcg gccgtccttc gcgtttatga
     2101 agggatggaa ggcacaacga ctgtcgaaca attccactat acgtttatca caatgggcat
     2161 tattactgtt gcttcagcag caatgttcat gcttctgaaa acaaccgatg gtaataattt
     2221 gatcaaaaga cagcgtaaat ctaa
//
LOCUS       DADXDL010000236         2183 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.242, whole genome shotgun sequence.
ACCESSION   DADXDL010000236 DADXDL010000000
VERSION     DADXDL010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2183)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2183)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2183
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.242"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..441)
                     /locus_tag="IRB70_004936"
     CDS             complement(<1..441)
                     /locus_tag="IRB70_004936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBC0634728.1"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSAL
                     DAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDV"
     gene            complement(579..1409)
                     /locus_tag="IRB70_004937"
     CDS             complement(579..1409)
                     /locus_tag="IRB70_004937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-1"
                     /protein_id="HBC0634729.1"
                     /translation="MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCF
                     LLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGM
                     EIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLT
                     EAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGA
                     GFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL
                     "
     gene            complement(1540..2094)
                     /locus_tag="IRB70_004938"
     CDS             complement(1540..2094)
                     /locus_tag="IRB70_004938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
                     /protein_id="HBC0634730.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLA
                     DVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGRWEEETDPGVRGIDQL
                     LANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTV
                     TTPYGPAVYMVQTRQAFERTRSDA"
BASE COUNT          518 a          492 c          495 g          678 t
ORIGIN      
        1 cacatctttt gtcaccaacg agcggctgcc tatcaccgca ccgtgcccga tcttgattcc
       61 gggcatgacc attgcctcag agccgatcca aacgtcattg ccaatgacag tattacctgc
      121 tttttggaag gcatcgagtg cgcttgagaa tgcaggttct tcctgcatat aaaagaacgg
      181 gaaagatgat gcccagtcgt accgatgccc ctgattgcca gccatgataa aggaagcccc
      241 actcccgata gagcagaaac taccgatgat caacttatca acgtcatcac ggtccggaaa
      301 cagataccgt gcgcagtcat cgaatgagtg cccatgatag tagccagagt aatagctgta
      361 ccgcccaact ttgatattgg ggttcttcac ttgctcagaa agcagcttgc ctttgaaggg
      421 gctatcaaag tagttggtca taagagatcc cgcggtctgt gactttgccg tctaacgttt
      481 gaaataaggg gcgccgagcg ccagcgaggg gagccaaaag cttgcttttg gccgtcccga
      541 cttgattgaa gggttgggcg attttgccat tagatttttt ataaatttag tgtgtttaga
      601 atggtgatcg catttttctt ggcttttatg cttgatgtta aattcgaccc caagtttcct
      661 gtaagtgcgg acacaaaaac atatttatgt cctgatttgc ttataataaa cccttcaaac
      721 catccgtttt gtaaggttct atttgctgtg aatcctgcac cagttttccc atacagtttt
      781 gtactattat ccagatcttg tagatacatg ttctctatgg tgttttctat ggctgagttt
      841 ttaactggga gattgtgatt aataatttta cgcaggaatt gaatttgttc ttctggtgaa
      901 atttttaagc tactttcgag ccatgcttct gttaatccgt tgtttctttc tttatctcca
      961 gagaagtctt gatttccata atcaaaatct ttgagataat tcttgatttt atttaatcca
     1021 attttttggg ttatttcttg cgaaacccaa acaacagaaa attgcatcca cgtctttggt
     1081 gtatgattgc tgttccagat ctccattcct ttgggggttt tatcccattt gaatatggtt
     1141 ttctgatcta ttatttccgc atcaaatgcc ataagtgata atgcgatctt gaaagttgaa
     1201 tctggtgcca tttgcgttgc acactttgct ttattgaatt gagcaatttc agcgtttgtg
     1261 gatgcatcgt aaagtaaaaa acaaccttca gttccttcaa ataatggaga tgcaacagta
     1321 gagatatctg ttgatgcact ggcgctgctg tagataatat ttgcaattat taaaaaaata
     1381 gcgaagttga tatgtattgt gtttttcata ataagtattg gtttggtaaa gggcttaatt
     1441 ttaacggcta acaattaatg aggctccggg ttcgcccaac gtttgacatg aggggcggcc
     1501 aagggcgcca gcccttggac gtccccctcg atggaagggt taggcatcac tgcgtgttcg
     1561 ctcgaatgcc tggcgtgttt gaaccatgta cacggctgga ccatatgggg tggttacggt
     1621 accttgcctc tcaaaccccg ctttctcgta gcatcggatc gctcgcaagt tgctcggcga
     1681 cgggtccgtt tggatcttgg tgacctcggg atcattgaac agcaactcaa ccagagctcg
     1741 aaccagcttg gttcccaagc ctttgcccag ttgtgatgca ttcgccagta actggtctat
     1801 tccgcgtact cctggatcgg tttcttcttc ccaccgtccg tccccgcttc caagagcaac
     1861 gtacgactgg gcatacccaa tcggctctcc attcagcatt gcaatgtatg gagtgacgga
     1921 ctcttgcgct aaaacgcttg gcaagtactg ttcctgtacg tcagcaagtg tcgggcgtgc
     1981 ttcttctccg ccccaccact cgacgatatg agatcgattt agccactcat agagcatcgc
     2041 aaggtcatgc tcagtcatga ggcgcagtgt gacggaatcg ttgctgttgg tcacgatgct
     2101 gtactttgtg atgcctaact ttgtttttgc gttgctcatg atgtctaact cccaatttgt
     2161 gtagggctta ttatgcacgc tta
//
LOCUS       DADXDL010000237         2101 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.243, whole genome shotgun sequence.
ACCESSION   DADXDL010000237 DADXDL010000000
VERSION     DADXDL010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2101
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.243"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(60..1025)
                     /locus_tag="IRB70_004939"
     CDS             complement(60..1025)
                     /locus_tag="IRB70_004939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012421200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBC0634731.1"
                     /translation="MSEDKFLSDYSPRDAVWDTQRTLTDSVGGIYQTAAEFERYALRM
                     ASCSGLLRFGWSTIMETGETRLRLRSAQFCRVRHCPVCQWRRTLMWQARFYQALPKIV
                     VDYPSSRWLFLTLTVRNCEIGELGTVLTAMNAAFKRMEKRKELSPVQGWIRATEVTRG
                     KDGSAHPHFHCLLMVQPSWFKGKNYVKHERWVELWRDCLRVNYEPNIDIRAVKTKTGE
                     VVANVAEQLQSAVAETLKYSVKPEDMANDPEWFLELTRQLHKRRFISTGGALKNVLQL
                     DRETNQDLVIADDVGDGTDDGKRTAFVWDSGKRRYKRAPEKDKSD"
     gene            complement(1891..>2101)
                     /locus_tag="IRB70_004940"
     CDS             complement(1891..>2101)
                     /locus_tag="IRB70_004940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001024536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634732.1"
                     /translation="RSEAVIPDRFKNLILLIDGLSFGTFGFHPHEGFEDELILYIQKT
                     NERVKTLFVKIDLNGIKFGFLRTHS"
BASE COUNT          581 a          550 c          441 g          529 t
ORIGIN      
        1 aaaaaaaata aaccaatagt cttatttcca ttcaggtatt caatattaat attcatacgt
       61 taatccgatt tatccttctc aggggcgcgt ttgtaacgcc gtttacctga atcccagaca
      121 aacgccgtcc gcttcccgtc atcagtgcca tcccctacat cgtcggcaat gacaagatcc
      181 tgattggttt ctcgatccaa ctggaggacg ttttttagcg ccccaccggt cgagataaaa
      241 cggcgcttgt gaagctgccg cgtcagctca agaaaccact caggatcgtt tgccatatct
      301 tccggtttaa cggagtattt cagcgtttca gcaaccgcgc tttgcagttg ctcggcaacg
      361 ttggccacaa cctcacctgt cttagttttt actgcccgaa tatcgatatt cggctcatag
      421 ttcacccgca agcaatcgcg ccagagttct acccaacgtt cgtgcttaac gtagttcttc
      481 cctttaaacc aagaaggttg caccatcagc agacagtgaa aatgcggatg tgcgctgcca
      541 tccttacctc gcgtcacctc cgtagccctg atccacccct gaacaggtga tagctccttt
      601 cgcttttcca ttcgcttaaa cgccgcattc attgctgtaa ggactgttcc aagttcacct
      661 atctcgcagt tcctgacagt taacgtcaga aacaaccatc gggaagacgg gtaatccaca
      721 acgattttcg gtagagcctg ataaaaacgg gcttgccaca tgagggttct tctccactgg
      781 cagacagggc aatgacggac acggcaaaat tgcgcactac gaagccgtag gcgcgtttct
      841 ccggtttcca tgatggtaga ccaaccaaaa cgtaacaaac cgctacagga ggccatacgg
      901 agtgcatagc gctcgaattc agcagcagtc tggtagatac ccccgacaga atcggtaagc
      961 gtgcgctggg tatcccaaac tgcatcacgg gggctgtagt ccgaaaggaa tttatcttct
     1021 gacattaagc ctgctccgat ctgggcaggc tgtgatttga tgtggtatat tcatcacgta
     1081 cctgtgcatt gcgagccagt acatgtcacc agagtttgcc gctgaggtga cacattcgaa
     1141 atgttgggga gtgttgacgc actccccaac gccgattaaa aacgcctcaa ttctgctcca
     1201 ttttctttga cctgtcaaaa cccactcaaa gcctcgtcat tactgggcta aaccactatt
     1261 tcatatccgc catttatccc ttaagtataa atacaaggat cacgcgcgag aattgcgcaa
     1321 aaaataacca caattttaac cccccaaaac aagcaccccc gaacggctta ccccaacctt
     1381 ttccacacac ccgatcacca aaacagggaa taaaaacaaa accctgtctt acaggtggat
     1441 ggcctcactt cgtgaaacca tccaccccgc ataagttttt taatcggtgg tgtcgtcaat
     1501 cactaaatcg gaaccccaaa ggggaccccc acgatttagc atttgacgag attaactctc
     1561 ggagatggca tcatgctttt aacggacttt aaaaaacggt gaacggatgc ggattttaat
     1621 ccgtgtctgt gaggcgttga gcaacgagca aagcgaggcg gtagaaagag agccagcggc
     1681 aggctcagga cgataatccg gggaaaatgt accactcgca gagtgttaac atttgacatc
     1741 ggattgtcta tcctgcattg gtgtcgagtt ggcaaggctg aggataatgc tgaggataat
     1801 gctgaggata atgcaggata gacagagcac tagagattgc atgcaatctc gtacctatca
     1861 cctcagcctg ccgctggctc ttttccagaa ctaagaatgc gttcttaaaa atccaaactt
     1921 gataccgttt aaatctattt tcacaaaaag agtttttacc ctctcgtttg ttttctgaat
     1981 atataaaatt aattcatcct caaaaccttc gtgcggatga aaaccaaatg tgccaaaact
     2041 taatccatca ataagcaaaa taaggttttt aaacctgtca ggaatcaccg cttcacttct
     2101 t
//
LOCUS       DADXDL010000238         2041 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.244, whole genome shotgun sequence.
ACCESSION   DADXDL010000238 DADXDL010000000
VERSION     DADXDL010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2041)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2041)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2041
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.244"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..906
                     /locus_tag="IRB70_004941"
     CDS             <1..906
                     /locus_tag="IRB70_004941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004144152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase"
                     /protein_id="HBC0634733.1"
                     /translation="DYYDVKLKESRLEKLESPSFTFYKLDLADRDGMAKLFETEQFER
                     VIHLAAQAGVRYSLENPYAYADSNLTGYLNILEGCRHNKVQHLLYASSSSVYGLNRKM
                     PFSTDDSVDHPVSLYAATKKANELMAHTYSHLYSIPTTGLRFFTVYGPWGRPDMALFK
                     FTKAMLEGKSIDVYNYGKMKRDFTYIDDIVEAIVRIQDVIPQPDPEWTVEEGSPATSS
                     APYRVYNIGNSSPVELMDYINALEQALGLEAKKNMMPIQPGDVLNTSAETQALYKTIG
                     FKPETPVQQGVKNFVDWYKEYYQYN"
     gene            956..1049
                     /locus_tag="IRB70_004942"
                     /pseudo
     CDS             956..1049
                     /locus_tag="IRB70_004942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227854.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
     gene            complement(1256..>2041)
                     /locus_tag="IRB70_004943"
     CDS             complement(1256..>2041)
                     /locus_tag="IRB70_004943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBC0634734.1"
                     /translation="PVQEPGSGKTRTARLWAYVRDDRNAGSQMPPAVWFAYSPDRKGI
                     HPQNHLAGYSGVFQVDAYGGYRVLYESGRITEAACMAHARRKTHDVHARVPTDITTEA
                     LQRIGELYVIEAEVRGCLAEQRLATRKARAAPLMQSLYDWIQTQMKTLSRHSDTAKAF
                     AYLLKQWEALNVYCSNGWVEIDNNIAENALRGVTVGRKNWLFAGSDSGGEHAAVLYSL
                     IGTCRLNNVEPEKWLRYVIEHIQDWPANRVRDLLPWKVDLTSQ"
BASE COUNT          497 a          507 c          486 g          551 t
ORIGIN      
        1 gattattatg atgtaaagtt aaaagaatct cgtcttgaaa aattagaatc tccctctttt
       61 actttttaca agttagatct cgctgaccgt gatggtatgg ctaaactttt cgaaacggag
      121 cagtttgaac gtgttatcca tcttgcggct caagcgggtg tacgttattc tctcgaaaat
      181 ccatatgctt acgcagattc caatttaacg ggctacctga atattttgga aggttgccgt
      241 cataataaag tgcaacatct attatatgct tcatccagtt ctgtctacgg tctaaaccgt
      301 aaaatgccat tctcaacaga tgattcagtc gaccaccccg tttcgttgta tgctgccaca
      361 aaaaaagcta atgagctgat ggcacatact tattcccatc tgtacagcat cccgacgaca
      421 ggactgcgct tctttacggt ctatggtccc tggggccgtc cggacatggc gttattcaaa
      481 ttcacgaaag cgatgctgga agggaaaagc attgatgttt ataactatgg taaaatgaag
      541 cgtgatttta cctatataga tgatattgtc gaagctattg ttcgtatcca ggatgtaatc
      601 cctcagcctg atcctgaatg gacagtcgag gaaggctctc cggctaccag ctccgcgcca
      661 tatcgggtct acaacattgg taacagctca ccggtggaac tgatggatta tatcaatgca
      721 ttggagcagg cattgggatt ggaagcgaag aagaatatga tgcctatcca gccgggtgat
      781 gtgttgaata ccagtgccga gacacaagct ctctataaaa ctattggttt taaaccggaa
      841 acgccagtac agcaaggtgt taaaaacttt gtagattggt ataaagagta ctatcaatat
      901 aactagttta ttggaagggg gggatagaaa cgttttcgcg cctccctcat accggcagca
      961 agtagcggat gtatcattac cgtatggcgg aaaagcgggt ggatgttgcg gacaaggtat
     1021 acacccgtga tctgtttggt aacgattagt tgtgcctgtc tgacccaggc ggttccctgc
     1081 cgccagtgtt cttctttctc tcccccgcta tatccctcac tacgcgtatt tctcgcacat
     1141 tcagattaac ctcaataaat tgtgatggac attacgatcc tgttcaaaag ccgtgcgggt
     1201 tgaaaacagg ttcgataagt taaacgtaag cggctcgcca gaaccgtatt gatatttact
     1261 gagaggtcag atcaactttc cagggcaaca gatcgcgtac ccggtttgcc ggccagtctt
     1321 ggatatgctc aataacgtaa cgcagccatt tttctggctc tacattgttc agacggcatg
     1381 tgccgatcag cgagtacaac accgccgcat gttcgccacc gctgtcggaa cccgcgaaga
     1441 gccagttttt ccggcctacg gtcactcccc gtaaggcgtt ctctgcaatg ttgttgtcga
     1501 tttccaccca gccattactg cagtacacgt tcagggcctc ccactgtttc agcaggtatg
     1561 cgaacgcttt tgccgtatcc gagtgacgcg acagtgtttt catctgagtc tgtatccagt
     1621 catacagtga ctgcatcagt ggcgcagctc tggcttttct tgtcgccaga cgctgttctg
     1681 ctaaacatcc ccggacttct gcctcgatga catacagttc accgatacgc tgcagggctt
     1741 ccgtggtgat gtcggttggc actcttgcat gcacatcgtg ggtttttctc cgggcatgag
     1801 ccatacacgc ggcttccgtt attctgccgg attcgtataa cacccggtaa ccaccgtaag
     1861 catcgacctg aaacacaccg ctgtaaccgg ccagatgatt ttgtggatgg atacctttcc
     1921 ggtccggtga gtacgcgaac cagaccgccg ggggcatctg tgaaccggca ttacggtcat
     1981 cacggacgta ggcccacagc cgggcagtcc ttgttttacc actgcccggc tcctggaccg
     2041 g
//
LOCUS       DADXDL010000239         1988 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.245, whole genome shotgun sequence.
ACCESSION   DADXDL010000239 DADXDL010000000
VERSION     DADXDL010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1988)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1988)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1988
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.245"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(241..1056)
                     /locus_tag="IRB70_004944"
     CDS             complement(241..1056)
                     /locus_tag="IRB70_004944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014640325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na(+)-translocating NADH-quinone reductase
                     subunit C"
                     /protein_id="HBC0634735.1"
                     /translation="MIRSGDFFDFHFDRDNNSMRKGKIIVASMMVLCVLIFVAAAAWF
                     MLFQGEMTEPTEEEKQAAILHAAGLMKSETQDKKSVETLYHRYIIQRHVNLDSGELVA
                     GSSADTARQKCEKLAPERDPAQVRQRCTVADVFFVKDKNNEIQQVIIPVTGKGAKSMM
                     HAFLALGLDGRTVRNLYYYQQRETPFLGARVEDANWRKQWPGKRLLDNSGHPALKIVQ
                     DKPEHADEYTVDGISGATLTSTGVEKSINYWMGPQGYGQFLQRLASDRNNLNL"
     gene            complement(1239..1745)
                     /locus_tag="IRB70_004945"
     CDS             complement(1239..1745)
                     /locus_tag="IRB70_004945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003846856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein disulfide oxidoreductase"
                     /protein_id="HBC0634736.1"
                     /translation="MLSKLRRWLREGAILLVVLAGVIILLDVWRSPQMPAMFDSTPLH
                     TLDGETVTLASISEERPVLLYFWASWCGICRFTTPDVARLQSEGESVMTIALRSGNDG
                     EVSRWLSRKRVTFPVVNDSGGEISRNWEISVTPTLVVVSKGQVVTTTSGWTSYWGMKL
                     RLWRAAMF"
     gene            complement(1735..1893)
                     /locus_tag="IRB70_004946"
     CDS             complement(1735..1893)
                     /locus_tag="IRB70_004946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001351253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBC0634737.1"
                     /translation="METLSTNLQLARLVGVQGTPATIIGDEMIPGAVSWETLEAVVKE
                     KLAVAHAQ"
BASE COUNT          504 a          559 c          438 g          487 t
ORIGIN      
        1 cgttatacat gacctggatc ataaaaatgt cagcagacga caagttatgt aaacttattt
       61 catcaaatcg tgatgaacac acacattatg cgttgataaa agggacgtta tctccctgtt
      121 tttctcatgg aattaacggc aaggcaggcg cggtaacaga ggaataaatc cccctgccga
      181 cagtgatatt attcattatc ggcaggcaga aataaaacgc gttattgcgt acagcaatat
      241 tcaaagatta aggttatttc gatcgctggc aagacgctgt aagaattgac catatccctg
      301 cggccccatc cagtagttaa tacttttctc aacgccggtt gatgtcaacg tcgcaccgga
      361 aataccgtca acggtatatt catcggcatg ttcaggttta tcctgtacta ttttcaatgc
      421 aggatgtccg ctgttatcta ataatcgttt ccctggccac tgtttgcgcc agttggcgtc
      481 ttccacccta gcccccagaa acggcgtttc ccgttgctga taataataca gatttctcac
      541 cgtacgaccg tccagcccca gagcaagaaa cgcatgcatc atggatttcg cacccttacc
      601 ggtaactgga atgataacct gctgaatttc attattttta tctttcacaa agaacacatc
      661 cgccaccgta cagcgctgac gaacctgcgc tgggtcgcgt tcaggggcaa gtttttcaca
      721 cttctgccgc gcggtgtccg cgctgctgcc agccaccagt tcgccggaat ctaaattaac
      781 atggcgttga ataatataac gatgatagag cgtttcgact gattttttat cctgggtctc
      841 tgatttcatc aggcccgcag cgtgtaaaat tgccgcctgt ttttcctcct ctgtcggctc
      901 cgtcatttct ccctggaaca gcataaacca tgccgccgcc gcaacaaaaa taaggacaca
      961 aagcaccatc attgatgcaa caataatttt acccttgcgc attgaattgt tatccctgtc
     1021 aaaatggaaa tcgaaaaaat cgcctgaacg tatcacagac tttcattcaa ttaaaacaga
     1081 tatgccatta tcaattcagg tttgcaacgt caggcagcgg taaaaaataa taactggcgt
     1141 cggtaaaaaa gcagcaaaaa taacagaaaa cacgctctcc gctcgtttta cacatcctta
     1201 caatgggtta aaaaatgccg ggtttccccg gcacgctatc aaaacatggc tgcccgccac
     1261 agacgtaact tcatgcccca gtagctggtc cagccgctgg tcgtagttac cacctgcccc
     1321 ttcgacacca ccaccagcgt tggcgtgacg ctgatttccc agtttcgtga tatctcaccg
     1381 ccgctatcat tcacgacggg gaacgtcacc cttttacgcg ataaccagcg ggaaacctcc
     1441 ccgtcattac cggaacgcag cgcgatggtc atgacgctct ccccttccga ctgcaaacgg
     1501 gcgacatccg gcgtggtgaa acggcagata ccgcaccagc tcgcccagaa gtagagcagc
     1561 accgggcgtt cttcactgat cgacgccagc gttacggttt ccccgtccag cgtatgcagc
     1621 ggcgtgctgt caaacatggc cggcatctgc ggagaacgcc agacatccag caggattatc
     1681 acgccagcca gcacaaccag taagatcgcg ccttcacgca gccagcggcg cagtttactg
     1741 agcatgggcc accgccagtt tttctttcac caccgcctca agggtctccc acgataccgc
     1801 gccggggatc atctcgtcgc caatgatggt tgccggcgtc ccctgaacgc caaccagccg
     1861 ggcgagttgc agattggtgc tcaacgtctc catgcttttc tcatcggggt cagtttggat
     1921 atagagaatt attgtactat aagggcttcc ccggcatgtc aatgccggtg tttacggttt
     1981 ctgtctgc
//
LOCUS       DADXDL010000240         1953 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.246, whole genome shotgun sequence.
ACCESSION   DADXDL010000240 DADXDL010000000
VERSION     DADXDL010000240.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1953
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.246"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(47..1732)
                     /locus_tag="IRB70_004947"
                     /pseudo
     CDS             complement(47..1732)
                     /locus_tag="IRB70_004947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_490592.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="conjugative relaxase"
     gene            complement(1732..>1953)
                     /locus_tag="IRB70_004948"
     CDS             complement(1732..>1953)
                     /locus_tag="IRB70_004948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000009331.1"
                     /note="type IV secretion system coupling protein; similar
                     to F plasmid TraD; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraD"
                     /protein_id="HBC0634738.1"
                     /translation="GIEQELKMKPEEEMEQQLPPGISESGEVVDMAAYEAWQQENHPD
                     IQQQMQRREEVNINVHRERGEDVEPGDDF"
BASE COUNT          367 a          656 c          474 g          456 t
ORIGIN      
        1 gggatgataa gtttatcacc accgactatt tgcaacagtg ccctcccccc tgccagcgat
       61 atgtgttcac cccggcatcc ttcatggcca tcagtgcact gcctgtaccg gttcgctgcc
      121 cgctgtcggt tatcaggacc tgtacgttat gacgtgcggc accatccagc agggttaacg
      181 tctctttcag ggagagtttt tcgccctggt cgacgataac ggtactgccc ggcgggaagg
      241 ccatgccttc cagcaactga cgacgtccgg ttatcagttc accggacagc cgttcatcct
      301 gcttcaggtt catctgcgag cgacggtcag cagcgataat ctgcacctcc cgcccctgct
      361 cccgggccat catgaccagt tcagccaccc gctcacgctg cccggctgca ccgccctgcc
      421 cggacacaat ggccagcgac gggcgatcct gtgccagaac actgacggca tcgctgtaac
      481 cggccgtccg ggggacactt ttctccggat gtacggtcac ccggttctgt ttcatgatgt
      541 cacgactgag tgcccggact gacagctcat cgagcacatg aatcccggac gtgaacagcc
      601 ccttctcacg atcgaggggg ataagctgct cacggctgat ggcctcatcg ataccggcgc
      661 gtgcccgttc aatcacacca ttttccggcg gcagtatgcc gaccgtcctg gccagcacgt
      721 ccgtatacgt gaactgcact tttcgttcac ttaatccggc aatggcctgt gtcaccgcct
      781 gctgcacatc cggcccgtcc tgtgaagcag gcccgggcgc ctgcgtgcgg atctccgcac
      841 gctgatccgc cgcgtcacga tatgcccgga tgtcgaaccc ggtttccttc agcgtctgca
      901 tccattcagc cattctgact tcaggatcga cgtgctgttt ggatttacgc gtatccagtg
      961 ccgccacatc ccgggatttc agcgaggcgt cttcaccgac ggcctcccgg atagcctgtg
     1021 agcgtccgga gaaggcttcc accggtacgc ccggcatctc ccacataccg tgcttaccga
     1081 ccacttcggt ttcataaccc agcgcctcaa cgcgctgacg taactcactc tgatatattt
     1141 tcccgaacgc aatccggttc gcgagcacgt tctcggaaaa tccggttttc cccactttgt
     1201 cactgctcag tgtcttccat tcgccgttat gctgcgtgac attagccacc accacatgcg
     1261 tgtgtaactg tgggtcctga tcgcgactgg tgtcatggtt aaacagtgcc atcaccagat
     1321 taccggtcag caccgtttct gactgtccgt ccgtcatcac ccgtgtggaa gccagcgcct
     1381 ccacctgacg gacagcaaaa tccacagcct ggttatgtgc atcaataaga cgtttatccc
     1441 ccccgagcat ggccatcatg gagacacttt tgggggcgga gaaggtcagg tcgtagccgg
     1501 gacgatgctt attactgcca tcctgcatgc ggcttaaatc cgccccgtcc ggcagcctgc
     1561 cctccagaag acgggtaaaa acatccttat cgacgctgcc ctgcagccca agctgttcag
     1621 ccccctgacc ggcccagcgt tctcccatgc tgcccagcac atagtaatta tccttgtcgg
     1681 tgtaatagtt tccggcactg cctgccgatt taacaacgct gaaactcaac atcagaaatc
     1741 atctcccggc tcaacatcct ccccgcgctc ccggtgcaca ttaatgttca cctcttcacg
     1801 acgctgcatc tgctgctgga tgtccggatg attttcctgt tgccatgcct cataagcggc
     1861 catatccacc acttcaccgg attcactgat cccgggtggc agttgctgtt ccatctcttc
     1921 ttccggtttc attttcagct cctgctcgat ccc
//
LOCUS       DADXDL010000241         1912 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.247, whole genome shotgun sequence.
ACCESSION   DADXDL010000241 DADXDL010000000
VERSION     DADXDL010000241.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1912)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1912)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1912
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.247"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..323)
                     /locus_tag="IRB70_004949"
     CDS             complement(<1..323)
                     /locus_tag="IRB70_004949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF932 domain-containing protein"
                     /protein_id="HBC0634739.1"
                     /translation="MRLASRFGYANQIRRDRPLTHEELMHYVPGIFGEDKHTSRSQNY
                     TYIPTITVLESLQREGFQPFFACQTRVRDPGRRGYTKHMLRLRRAGEINGEHVPEIIL
                     LNSHDG"
     gene            complement(423..656)
                     /locus_tag="IRB70_004950"
     CDS             complement(423..656)
                     /locus_tag="IRB70_004950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001119724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF905 family protein"
                     /protein_id="HBC0634740.1"
                     /translation="MPGYTEYVLAEGSFSYGQAVAVITAYRNVFIQDDPGMHFRRVIR
                     NAEGQRRWRCRNSEPDAGKVLNTRLASDGLLRQ"
     gene            714..1391
                     /locus_tag="IRB70_004951"
     CDS             714..1391
                     /locus_tag="IRB70_004951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001743492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBC0634741.1"
                     /translation="MSIIFNGHYRMKHRTWITEALRLHFEEHLPRVVAGRRLGVPKST
                     VCSMFVRFRRAGLSWPLPAGMSEQELDACLYGQFSTVPVVRPESTVISEAPVVKKRPR
                     RPNFPYEFKIALVEQSLQPGACVAQIARENGINDNLLFNWRHQYRKGGLLPSGKNMPA
                     LLPVTLTPEPDNKIPAPAQEPEQINTPSDSLCCELVLPAGTLRLKGKLTPALLQTLIR
                     EIKGSSH"
     gene            1391..1738
                     /gene="tnpB"
                     /locus_tag="IRB70_004952"
     CDS             1391..1738
                     /gene="tnpB"
                     /locus_tag="IRB70_004952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_858152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBC0634742.1"
                     /translation="MISLPAGSRIWLVAGITDMRNGFNGLASKVQNVLKDDPFSGHLF
                     IFRGRRGDQIKVLWADSDGLCLFTKRLERGRFVWPVTRDGKVHLTPAQLSMLLEGINW
                     KHPKRTERAGIRI"
     gene            1758..>1912
                     /locus_tag="IRB70_004953"
     CDS             1758..>1912
                     /locus_tag="IRB70_004953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634743.1"
                     /translation="MDTSLAHENARLRALLQTQQDTIRQMAEYNRLLSQRVAAYASEI
                     NRLKALVA"
BASE COUNT          440 a          524 c          508 g          440 t
ORIGIN      
        1 ccgtcatgag agttgagcag aataatttca gggacatgtt ctccgtttat ctctccggcc
       61 cgccgcagac gcagcatgtg ttttgtgtat ccccggcggc ccgggtcgcg cacacgggtc
      121 tggcaggcga agaatggctg aaagccttcc cgctgcaggc tttccagtac ggtgatggtg
      181 gggatgtacg tatagttctg gcttcgggac gtgtgtttat cttccccgaa aatccccggc
      241 acatagtgca tcagttcttc gtgtgtcagc ggacggtcac ggcgtatctg gttcgcataa
      301 ccaaaacgac tggctagtcg cataatttgc tccttatcgg tggttaagat ttactggtgt
      361 aataaatgaa aaagccacgt ctcccggaga agacgcggcc tgatgggtga aatgaatgac
      421 gtttattgtc tgagaagacc gtcactggcg agccgcgtat taagcacctt tccggcatcg
      481 ggttcagaat tccggcagcg ccagcgtcgc tgaccttccg cgttgcggat aacccgacgg
      541 aaatgcattc ccgggtcatc ctggataaac acattgcggt aagcggttat gacagcaacc
      601 gcctgcccgt atgagaaaga tccttcagcc aggacatact ctgtgtaacc cggcatatct
      661 gtaaccggct catttaaacc gtctggtctg tttcctccgg ctctacaaaa ataatgtcca
      721 tcatttttaa tggacactat cgtatgaaac accggacctg gatcactgaa gctttacgtc
      781 ttcactttga agaacattta ccccgggttg tggccgggcg tcgcctgggt gtaccaaaat
      841 caacagtttg tagtatgttc gtgcgctttc ggagagctgg cctttcgtgg cctttgcccg
      901 caggcatgtc ggagcaggaa cttgatgcct gcctttacgg acaattttcc acggtaccag
      961 tcgtacgtcc tgaaagcacc gttatatccg aagcccccgt ggtaaaaaaa cgtccccggc
     1021 ggcccaactt cccttatgag tttaaaatcg ccttagtgga gcagtcactg cagcccggag
     1081 cctgtgtggc gcagatcgcc cgggaaaacg gaatcaatga taacctgctc ttcaactggc
     1141 gccatcaata ccggaaaggt ggcctgctgc cttccggaaa aaatatgccg gcactgcttc
     1201 ccgtgacgtt aacgccggag ccggataata aaatcccggc ccccgcacag gaaccagagc
     1261 agataaatac accgtccgac agtctgtgtt gtgagctggt tctgccggcc ggaactctca
     1321 ggcttaaagg taaactgacg ccggcgttat tacagacact tatccgcgaa ataaaaggga
     1381 gcagccactg atgatatctc tccctgcagg ttcgcgtatc tggctggttg caggtatcac
     1441 cgatatgcga aatggcttta acggcctggc atcaaaagtt cagaacgtcc tgaaggatga
     1501 cccgttctcc ggacacctgt tcatcttccg cggacgccgg ggtgaccaga taaaagtgtt
     1561 gtgggctgac agtgacggac tgtgcctctt caccaaacgc ctggagcggg gccgcttcgt
     1621 ctggccagtc acccgtgacg gcaaggtgca ccttactccg gctcagttat ccatgcttct
     1681 tgaaggtatc aactggaagc acccgaaacg aacggaacgc gctggaatcc gcatataacc
     1741 cgttgtaaag tgaggatatg gacacctcac ttgctcatga gaacgcccgc ctgcgggcac
     1801 tgttgcagac gcaacaggac accatccgcc agatggctga atacaaccgc ctgctctcac
     1861 agcgggtggc ggcttatgct tccgaaatca accggctgaa ggcgctggtt gc
//
LOCUS       DADXDL010000242         1905 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.248, whole genome shotgun sequence.
ACCESSION   DADXDL010000242 DADXDL010000000
VERSION     DADXDL010000242.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1905)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1905)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1905
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.248"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            42..326
                     /gene="traQ"
                     /locus_tag="IRB70_004954"
     CDS             42..326
                     /gene="traQ"
                     /locus_tag="IRB70_004954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001617873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     chaperone TraQ"
                     /protein_id="HBC0634744.1"
                     /translation="MISKCRFSLPRLDITGMWVFALGVWFHIVARLVYSKPWMAFFLA
                     ELIAAILVLFGAYQVLDAWIARVSLEEREALEARQQAMMEGQQEGGHVSH"
     gene            313..858
                     /gene="trbB"
                     /locus_tag="IRB70_004955"
     CDS             313..858
                     /gene="trbB"
                     /locus_tag="IRB70_004955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000052622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type-F conjugative transfer system pilin
                     assembly thiol-disulfide isomerase TrbB"
                     /protein_id="HBC0634745.1"
                     /translation="MSLTKLLPVILLMMATGVQASTRDEIERLWNPQGMAVQPAQPAA
                     DTSARTEKPAPRWFRLSNGRQVNLADWKVVLFMQGHCPYCHQFDPVLKQLAQQYGFSV
                     FPYTLDGQGDTAFPEALPVPPDVMQTFFPNIPVATPTTFLVNVNTLEALPLLQGATDA
                     ASFMARMDTVLQIYGEEKGAK"
     gene            788..1135
                     /gene="trbJ"
                     /locus_tag="IRB70_004956"
     CDS             788..1135
                     /gene="trbJ"
                     /locus_tag="IRB70_004956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001444236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-type conjugative transfer protein TrbJ"
                     /protein_id="HBC0634746.1"
                     /translation="MPPVLWRGWIPFCRYTERKKVRNKQVVLLIAGISGIATGIIVSL
                     NIPFIRQGLFYPASPVEIVVSLCLTFSVSVVFFVGAIVGWISVSEIYYSRMTCLHESS
                     EISEGTYDERKNK"
     gene            1083..1508
                     /gene="trbF"
                     /locus_tag="IRB70_004957"
     CDS             1083..1508
                     /gene="trbF"
                     /locus_tag="IRB70_004957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001323332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F-type conjugal transfer protein TrbF"
                     /protein_id="HBC0634747.1"
                     /translation="MNHQKYQRELMMKEKINDTEPGIKQIEREIERGCDNAKKYFWLF
                     VVFFAAGLIVRNVMHDFFSAGIDSWKADPELNNFRYMWNTLMYVIPIMLYALAAGFLA
                     AASLSPLCEIIFGGVRIFLLKRRMRRENTLREGSNNASH"
     gene            1495..>1905
                     /locus_tag="IRB70_004958"
     CDS             1495..>1905
                     /locus_tag="IRB70_004958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001137361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraH"
                     /protein_id="HBC0634748.1"
                     /translation="MLRIKPLLVLCAALLTFTPAASADVNSDMNQFFNKLGFASNTTQ
                     PGVWQGQAAGYAYGGSLYARTQVKNIQLISMTLPDINAGCGGIDAYLGSFSFINGDQL
                     QRFVKQIMSNAAGYFFDLALQTTVPEIKTAKDFLQ"
BASE COUNT          440 a          445 c          507 g          513 t
ORIGIN      
        1 agacatgaat attctcatgt aaataataac cggagtttaa catgataagt aaatgcagat
       61 tctctttacc ccggcttgat attacgggaa tgtgggtatt tgctctgggt gtctggtttc
      121 atatcgtcgc ccgtcttgtt tacagcaaac cctggatggc tttttttctg gcggagttga
      181 ttgcggccat ccttgtgctg ttcggcgcat accaggtgct ggatgcatgg attgcacgtg
      241 tcagcctgga agagcgtgag gcactggaag ccaggcaaca ggccatgatg gaagggcagc
      301 aggagggcgg acatgtctct cactaaatta ctgccggtca ttttgttgat gatggccaca
      361 ggtgtgcagg cctccacccg ggatgaaatt gaacgactct ggaatccgca gggtatggcc
      421 gtgcagcctg cacaaccggc agcagacaca tcagccagaa cagaaaagcc ggctccccgc
      481 tggttccgcc tcagcaacgg caggcaggtt aacctggccg actggaaggt ggtgctgttt
      541 atgcaggggc attgccctta ctgtcaccag tttgacccgg tactgaaaca gctggcacag
      601 cagtacggct tttctgtttt tccctacacc ctggatggtc agggtgatac cgcctttccg
      661 gaagcattac cggtgccacc ggacgtgatg cagaccttct tcccgaatat cccggtggcc
      721 acaccgacca ccttcctggt caacgtcaac acacttgagg cattaccgct tttgcagggg
      781 gcaacggatg ccgccagttt tatggcgcgg atggataccg ttctgcagat atacggagag
      841 gaaaaaggtg cgaaataagc aggtggtgtt actcattgcc ggaatatccg gcatcgcgac
      901 gggaataatc gtcagcctga atatcccctt tatccgtcag gggctttttt atcccgccag
      961 ccctgtggaa attgtcgttt cgctgtgtct taccttttct gtttctgttg tgttttttgt
     1021 gggggcaatt gtgggatgga tttcggtgtc tgaaatatat tacagccgca tgacctgtct
     1081 gcatgaatca tcagaaatat cagagggaac ttatgatgaa agaaaaaata aatgatacag
     1141 aaccgggaat caaacaaatt gaaagggaga ttgaacgtgg ttgtgataat gcaaaaaaat
     1201 acttctggct ttttgtggtt ttctttgctg ccggattgat tgtaaggaac gttatgcatg
     1261 attttttcag tgccggtatt gattcgtgga aagctgaccc ggaattaaat aattttcgtt
     1321 atatgtggaa caccctgatg tatgtcattc cgattatgtt atatgcgctt gcagctggtt
     1381 ttcttgctgc ggcttctctg tcgccgttgt gcgaaataat atttgggggt gtccggatat
     1441 tcctgctgaa acgccgtatg cgccgggaga acacattaag ggagggcagc aataatgctt
     1501 cgcattaaac ctcttctggt tctttgtgcc gctttactga cgttcacacc cgcagcgtca
     1561 gcggatgtga acagcgatat gaatcagttc tttaacaagc tgggcttcgc ctccaatacc
     1621 acacagccgg gcgtctggca ggggcaggcc gccgggtatg cctatggtgg ctccctgtat
     1681 gcccgcaccc aggtcaaaaa tatccagctg atttccatga cgctgccgga tatcaatgcc
     1741 ggatgtggcg gcatcgacgc ctatctcggc tcgttcagtt ttattaatgg cgatcagttg
     1801 cagcgttttg ttaagcagat tatgagcaat gctgccggtt acttttttga ccttgccctg
     1861 cagacaacgg tgccggaaat aaaaaccgca aaagacttcc tgcag
//
LOCUS       DADXDL010000243         1884 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.249, whole genome shotgun sequence.
ACCESSION   DADXDL010000243 DADXDL010000000
VERSION     DADXDL010000243.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1884
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.249"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..1568)
                     /locus_tag="IRB70_004959"
     CDS             complement(<1..1568)
                     /locus_tag="IRB70_004959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter outer membrane beta-barrel
                     domain-containing protein"
                     /protein_id="HBC0634749.1"
                     /translation="MHSWKKKLVVSQLALACTLAITSQANAATNDISGQTYNTFHHYN
                     DATYADDVYYDGYVGWNNYAADSYYNGDIYPVINNATVNGVISTYYLDDGISTNTNAN
                     SLTIKNSTIHGMIYSECMTTDCADRANDYYHDRLALTVDNSTIDDNYEHYTYNGTYNN
                     AADTHVVDVYNIGTAITLDQEVDLSITNNSHVAGITLTQGYEWEDIDDNTVSTGVNSS
                     EVFNNTITVKDSTVTSGSWTDEGTTGWFGNTGNASDYNGDGWNADDVALAVIAHPYAD
                     NAMQTTATFDNSTLMGDVFFSSNFDENFFPQGRDSYRDADGDVDTNGWDGTDRLDLTL
                     NNGSKWVGAAMSAHQVDLGSDIGTDTDGDGDVDNDILDGKIDKNSPLDGIYDAYAMGS
                     DATATLIDIAANSLWPSSTVGVENSDSEYSEFDHIIGNEVYQSGLFNVTLNTGSQWDT
                     TKTSLIDTLSINSGSTVNVADSTLISDSISLTGLSALNINEDGHVATDSLTVDNSTVT
                     ISDEVSAGWAVGDAA"
BASE COUNT          564 a          413 c          385 g          522 t
ORIGIN      
        1 gcagcatcac ctacagccca accagcagaa acttcatcag aaatggttac ggtactgttg
       61 tcgacagtca gtgaatcagt tgcaacatga ccatcttcgt tgatgttcag cgcagaaaga
      121 cctgtcagag agatagagtc agaaatcagc gttgaatcag caacattaac agttgaacca
      181 ctgttgatgc tcagagtatc aatcagagaa gttttggtgg tatcccactg tgaaccggtg
      241 ttcagggtca cattgaacag accgctctgg taaacttcgt taccgatgat gtgatcaaat
      301 tcgctatatt cagagtcgct attttctaca ccaacagttg atgaaggcca caggctgtta
      361 gctgcgatat cgatcagagt tgcagttgcg tcggaaccca tcgcataagc atcgtaaata
      421 ccatccaacg ggctattttt atcgatctta ccatcaagga tatcgttatc aacatcaccg
      481 tcaccatcgg tatctgtccc aatatctgaa cccagatcaa cctgatgtgc agacattgcc
      541 gcaccgaccc acttgctgcc attgttcagg gtcagatcca ggcgatcagt accatcccaa
      601 ccgttagtat ctacatcacc atcagcatca cgatagctat cacgaccttg tgggaagaag
      661 ttctcatcaa aattacttga gaagaataca tcgcccatca gtgtagaatt gtcgaatgtt
      721 gcagtggttt gcatggcgtt atcagcatat ggatgtgcaa taacagctaa tgcaacatca
      781 tcagcattcc acccatcacc attgtaatca ctggcattac cagtattacc aaaccaacca
      841 gtagtacctt catcagtcca tgaaccagag gtcacggtag aatctttaac agtgatggtg
      901 ttattaaata cttcgctgct gtttacacca gtgctgacag tgttgtcgtc gatatcttcc
      961 cactcataac cctgagtcag cgtaataccc gctacgtgag agttattagt gatggacaga
     1021 tcaacttcct gatccagagt gatagccgta ccaatgttat aaacgtctac aacatgagta
     1081 tcagcggcat tattgtaggt gccgttatat gtgtagtgtt cgtagttgtc gtcgattgtt
     1141 gaattatcaa cagtcagcgc cagacgatca tggtaataat cattcgcacg atcagcacaa
     1201 tcagttgtca tgcactcgga ataaatcata ccgtgaatag tgctgttttt gattgtcaga
     1261 ctattggcat tggtattggt agaaataccg tcgtccagat agtaggtaga aatcacgccg
     1321 ttaacagtag cgttattaat gaccgggtag atatcgccgt tgtaatagct atcagcggca
     1381 tagttgttcc agcctacata accatcatag taaacgtcat cagcataggt ggcgtcgttg
     1441 tagtgatgaa aagtattgta agtttgacca gaaatatcgt tggtcgctgc attagcctga
     1501 gaggtgatag ccagagtgca agccaatgct aattgtgata ctacaagttt ctttttccag
     1561 gagtgcattt gtcatccctc ctcagggacg taataagttg atccatcaat tatcaatgca
     1621 tagaaaacat attatgtttc gcgctaacga ttatgcggcg ttattgagga atggttcaat
     1681 tattctttcc ccgaagtccg gttacggaca tatataaagc acggaggaac acacaaagaa
     1741 aaaattgata aaggcttaat gtttcaacaa gttaacagga tttccatttt taaagcatat
     1801 gcatttaaaa tatcaaacac acaaaccaga caaataatct atcaataacc aatgaacttt
     1861 aaatcattcc gtttttgata acgc
//
LOCUS       DADXDL010000244         1856 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.250, whole genome shotgun sequence.
ACCESSION   DADXDL010000244 DADXDL010000000
VERSION     DADXDL010000244.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1856)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1856)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1856
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.250"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            143..1435
                     /gene="sctN"
                     /locus_tag="IRB70_004960"
     CDS             143..1435
                     /gene="sctN"
                     /locus_tag="IRB70_004960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311757.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system ATPase SctN"
                     /protein_id="HBC0634750.1"
                     /translation="MKKLKLLNKYSYLHSINGSLIEAELDDVSVGEVCEIYASWQANE
                     RIARAQVVGFRNGKTLLNLIGSSVGLTRTAVLKPTGEQLTIQISDAFLGSVLNASGQI
                     MERFVPDTPGERGNLRLIDELPPSYQERRVINTPLETRIRVIDGVLTCGIGQRVGIFA
                     SAGCGKTVLMHMLVNNTEADVFVIGLIGERGREVTECAESLKKSVNAAKCVLVYATSD
                     FSSVDRCNAALMATTVAEYFRDRGKRVVLFIDSMTRYARALRDMKLAAGEPPARRGYP
                     ASVFDSLPRLLERPGPTLKGSITAFYTVLLEGEDESDPLGDEIRSILDGHIYLSRKLA
                     GQGHYPAIDVLKSVSRVFGQVTDEKHRDNAARVRKILTTLEDLQVFIDLGEYRAGQNV
                     ENDFAMNARPKLTNWLKQSVNEKMPMSETLKELERIVK"
     gene            1425..>1856
                     /locus_tag="IRB70_004961"
     CDS             1425..>1856
                     /locus_tag="IRB70_004961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311756.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion protein"
                     /protein_id="HBC0634751.1"
                     /translation="MLSKVNRLIRRTAQSLAACEASLQKLNVEKEKLVEKERLYDMQL
                     KNLQSLLDMKELLGEVVFRQDIFYSLRKVAVIQQQIAEINLEKQKIAERRKILNKEIV
                     QQQAQRKHWWLKGEKYDRLKKRIKKQLLNQMLYQDELEQEEK"
BASE COUNT          593 a          328 c          454 g          481 t
ORIGIN      
        1 attcgtcgtt ttatcaaaaa acttattgaa tctagttatc gagacctcga agtactttcg
       61 tacggggaac taacggaaaa tgttcccgtt aatattctga aaactattta ggataatgtc
      121 ttgcgatatg gagcatgctg gtatgaaaaa attaaagcta ttaaataaat acagctactt
      181 acatagcata aacggctcgc tgattgaagc agagcttgac gacgtttcag tgggcgaagt
      241 atgcgaaatt tatgcgagct ggcaagcaaa tgaacgtata gccagggctc aggtcgttgg
      301 ctttcgcaat ggaaagacat tattaaacct tataggcagc tctgtggggc ttacacgtac
      361 tgcagttttg aaaccaacgg gagagcagtt aaccatacag atcagtgatg cctttcttgg
      421 ttcagttttg aatgcttctg gtcaaattat ggaaaggttt gtcccggaca ctccaggcga
      481 aaggggaaat ttacgcctga ttgatgaact gccaccgtcg tatcaggaac gtcgagttat
      541 taatacacca ctagagacac ggataagagt cattgatggc gtactgacat gtggcattgg
      601 tcaacgtgtt gggattttcg catcggctgg ctgtggcaaa acggttttaa tgcatatgct
      661 tgtaaacaac actgaagctg atgtgtttgt tattggcttg attggcgaac gtggaaggga
      721 agttacggaa tgcgcggaat cgctgaaaaa atcagtaaat gcagcaaaat gtgttttggt
      781 ttatgccacc tctgattttt cgtcagtaga tcggtgtaat gccgccctga tggcgacaac
      841 cgtggcagag tattttagag atcgtggaaa gagagttgta ctttttatcg actcaatgac
      901 gcggtatgca cgagcactac gcgatatgaa gctggcagcg ggtgaaccac ctgccaggcg
      961 tggttatcct gcttctgttt ttgacagttt acctcgctta ctggagaggc cgggaccaac
     1021 actaaaagga agtattactg cgttttatac cgtattactg gagggggagg atgaatcaga
     1081 cccactgggt gatgaaattc gctcaatcct tgatggccat atctatctaa gtcgcaaact
     1141 cgctgggcaa ggtcattatc cggcaataga tgttctaaaa agtgtgagtc gagtatttgg
     1201 tcaggtcact gatgaaaaac acagagataa tgctgcacgg gtaaggaaga tcctcacaac
     1261 tttggaagat ctacaggtgt ttattgattt aggggaatat cgcgctgggc aaaatgttga
     1321 aaatgatttt gctatgaatg cccggcctaa actcacaaat tggttaaaac agtcagttaa
     1381 tgaaaaaatg ccaatgagtg aaacgctaaa agagcttgaa cgaattgtta agtaaagtta
     1441 atcgacttat cagaagaaca gcgcagagcc tggctgcatg tgaagcatca ttacaaaagt
     1501 taaatgtaga aaaagaaaag ttagtcgaaa aggaacggct gtatgatatg caacttaaaa
     1561 acctacagtc actgttagat atgaaggagt tactcggcga agtagtattt cgccaggata
     1621 tattttactc gttacgtaaa gttgcagtca ttcagcagca gatcgctgag ataaatcttg
     1681 aaaagcaaaa aatagcagag cggcgaaaaa tacttaacaa ggaaatagtt caacagcaag
     1741 cacaaagaaa acactggtgg ctaaaaggag aaaagtacga tcgactaaag aagcgcatca
     1801 aaaaacaact tttaaatcag atgctttatc aagacgagct tgaacaggag gagaaa
//
LOCUS       DADXDL010000245         1815 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.252, whole genome shotgun sequence.
ACCESSION   DADXDL010000245 DADXDL010000000
VERSION     DADXDL010000245.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1815)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1815)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1815
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.252"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..125)
                     /locus_tag="IRB70_004962"
     CDS             complement(<1..125)
                     /locus_tag="IRB70_004962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_047234906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBC0634752.1"
                     /translation="MRRTFTAEEKASVFELWKNGTGFSEIPNILGSKPGTIFTML"
     gene            complement(196..468)
                     /locus_tag="IRB70_004963"
                     /pseudo
     CDS             complement(196..468)
                     /locus_tag="IRB70_004963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558235.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(643..765)
                     /locus_tag="IRB70_004964"
     CDS             complement(643..765)
                     /locus_tag="IRB70_004964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634753.1"
                     /translation="MMIILTGSIFTAVEENLCAAASGFSDATAHGLTATSALTT"
     gene            1055..>1815
                     /locus_tag="IRB70_004965"
     CDS             1055..>1815
                     /locus_tag="IRB70_004965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsule assembly Wzi family protein"
                     /protein_id="HBC0634754.1"
                     /translation="MIKITSIAVTLGLLSSLGAQAYAAGLVVNDNDLRNDLAWLSVRG
                     VIHLSLSTWPLSQEEIARALKKAKPSYSSEQVVLARINQRLSALKADFRVTGYTSTDQ
                     PGTPQGFGQTQPADNSLGLAFNNSGEWWDVHLQGNVEGGERISNGSRFNANGAYGAVK
                     FWNQWLSFGQVPQWWGPGYEGSLIRGDAMRPMTGFLMQRAEQAAPETWWLRWVGPWQY
                     QISASQMNQYTAVPHAKIIGGRFTFTPFQSLELGAS"
BASE COUNT          424 a          459 c          458 g          474 t
ORIGIN      
        1 cttaacatag tgaagatcgt tccgggtttt gaacccagga tattcggtat ttcactgaag
       61 cctgttccgt tcttccatag ttcaaaaaca gaggcttttt cctctgctgt aaatgttcgt
      121 ctcattcaaa aaacctccgc aaccccatgt tttcacataa ctgttgcgtt gaccaattga
      181 atctacagca gcctgcttta gtatttcttt ttccatctca aggcacttta tctgcgcttt
      241 aagctgctga atttcgcgtt gttcagggct aatagcatta ccagcgggct caataccctg
      301 aagttcctgc ttatacaacc gtatccattt acgcaaatgg tcagggttga gctcaagtgc
      361 cagcgcgcct tctctgacat cacgctggta tttaaccacc acctgctcga aagcttcaag
      421 cttgaactcc gcggaaaagg tacgtttagt ccgacgagtt ttgattatgc atcacctcat
      481 tttcactgtt ttaacattaa caggatttcg aggtgtcctg aattatcgat ccactacagt
      541 aacaacactc ccaattgtga ccgaaatccc gtaaacttag cgcagccaaa aataatgacc
      601 tgaccaatta ttcatccaca ggtcgataaa aaattaagtc gttcaggtag tcagtgcgct
      661 ggtagctgtt aagccatggg cggtagcgtc gctgaagccg cttgctgctg cacagaggtt
      721 ctcttcaacg gctgtaaata tcgacccggt caggatgatc atcatcaata gatatctatc
      781 aattttctat ggatttcctc agaagttgtt caggagcggc tgctgatatc gcctggacat
      841 taactttcat gtctcattga tggcctgtag ggtaaattcg tcgacattgt gagcttagtg
      901 gatgttataa ggctaacaag cagcttaggg taaatgtact tgcctcgccg gtgttgcaca
      961 gcgaagtcag ctggtgccgc gagcgctctc tatcttggta ttcccctcat tctcattgag
     1021 atacgacagc agggctgaaa atggatcttg tacaatgata aaaattacga gcattgccgt
     1081 gacgttgggt ttgctttcct cactgggagc ccaggcttac gcggccgggt tagtggtaaa
     1141 tgacaacgac ttgcgtaacg acctggcctg gctttccgtt cgtggggtca tccatctgag
     1201 cctgtcgacg tggccgctga gccaggaaga gatcgcccgg gcgctgaaaa aggccaaacc
     1261 ttcctattct tctgagcaag tggtgctggc tcgtatcaac cagcgactgt ctgctttaaa
     1321 agccgatttc cgggtcaccg gctacacctc aaccgaccag ccgggcactc cgcaggggtt
     1381 tggccagacg cagccagcag ataactcgtt aggcctggcg tttaacaaca gcggcgaatg
     1441 gtgggatgtc cacctccagg gtaacgtcga agggggggag cggatcagta acggctcgcg
     1501 cttcaacgcc aacggcgcct acggtgcggt gaaattctgg aaccagtggc tctcctttgg
     1561 ccaggtaccg cagtggtggg gaccgggtta tgaaggaagc ttgatccgcg gggatgcgat
     1621 gcgaccgatg accggttttc tgatgcagcg agccgagcag gcggcgccgg aaacctggtg
     1681 gctgcgctgg gtgggtccat ggcagtacca gatctccgcc agccagatga atcaatatac
     1741 cgctgtgcct catgccaaaa ttattggcgg acgttttacc ttcacgccgt tccagtcatt
     1801 agaattaggt gcgtc
//
LOCUS       DADXDL010000246         1775 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.254, whole genome shotgun sequence.
ACCESSION   DADXDL010000246 DADXDL010000000
VERSION     DADXDL010000246.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1775
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.254"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(477..1430)
                     /locus_tag="IRB70_004966"
     CDS             complement(477..1430)
                     /locus_tag="IRB70_004966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016248779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634755.1"
                     /translation="MNESYYFRTSDPDYIRHAPSRLEILSKAFTTIITQQESEHELQR
                     LIHLLNKLKGSNRCYNIIAQKLRQCRNGSPCNSLICPHCQRERILAQLAMLHVLPGNS
                     AEYVGVVLFFNKDTQTPPPWKNTDALRAQIGRYKQRISRVLNRLGYAGPATGTFSMMR
                     HMPDGPEARIFWVPQLCLFLPNDSTLIKGLKAHMSRSSGEFIDATTVNTPVIVPRYKD
                     PARLLSCALDPAWHTTDYTLTDKDALVKSRVAPLKGRTLLKSLLALDSLGTGAVSFSF
                     GQPQGKCIDFPVMQPLQCTFVVDQIAVERRVTLATTAFSLL"
BASE COUNT          448 a          456 c          403 g          468 t
ORIGIN      
        1 cggtcccctc tcagcatcct catatcatta cattaaccaa actcaacact gagcaatttg
       61 aaagtcaaaa ccccagtcgc gaggacgggc tccgcccatg atttgctcca ctccggtcgc
      121 aaatctttcc ccctgttcag gctgacgcct tccctcactc gctgcgctcg ttcgccatgt
      181 tgtttcatga ctggagaagc ggatgaagcc tccgttatgc tgcgcgtccc caggctctcc
      241 gttgcgctca atggcaatgg tgctcgctga ccgctccccc attgtgtgta gaatattcac
      301 tggcagaaac gcagaaagcc ctcgcagatg cgctaactcg tcagttgatg gcaaggatcg
      361 ggtgcgcaga ggcatccgta agaccctgca gaaaacagac ggttacgtta aaatcggaac
      421 agttggaatt ttaaagtgca tcagtgccag cagaatcaca ggcgagcgct gcagttttac
      481 aacaacgaaa atgcagtggt tgccagtgtt acccgtcgtt ccactgcaat ttgatcaaca
      541 acaaaagtgc attgcagtgg ctgcattacc gggaaatcaa tgcactttcc ctggggttgc
      601 ccaaacgaaa aagaaacggc acctgttccc agtgagtcca gggccagtaa actttttaac
      661 agtgtccgac ctttcaatgg cgctactctg gacttaacaa gagcgtcttt atcagtcagt
      721 gtataatccg ttgtgtgcca ggcgggatcc agggcgcatg aaagtagcct ggcggggtct
      781 ttatacctgg gcacgatcac cggcgtgtta actgtcgtcg catcaataaa ttccccacta
      841 cttcgcgaca tatgcgcttt tagcccctta atcaacgtac tgtcattggg caggaacaaa
      901 cacaactgtg gaacccagaa aatacgcgct tctgggccat caggcatatg gcgcatcata
      961 ctaaaggtgc ctgtggccgg accggcgtac cccagtcggt taagtacccg gcttatcctc
     1021 tgcttataac gaccaatttg cgccctgagc gcatcggtgt tcttccatgg cggcggagtt
     1081 tgcgtatcct tgttgaaaaa caggaccact cccacatatt ctgctgaatt ccccggcagg
     1141 acatgcagca tagccagttg cgccagaatg cgttcccgct ggcaatgcgg gcatataaga
     1201 ctgttgcatg gagatccgtt tctgcactgc ctgagttttt gagcaatgat gttgtagcag
     1261 cgattgctgc ctttcagttt atttagtaaa tgaataagac gctgcaattc atgctcactt
     1321 tcctgctgcg taataatagt ggtgaatgct ttacttaaaa tctcaagcct tgacggtgcg
     1381 tggcgaatgt aatccgggtc tgatgttctg aagtaataag attcgttcat ttaatattcc
     1441 tggttgtatt cattaccctg ccacctgagt aaagcaacag ggtaatgtgt ccggttttta
     1501 ttcaggaaaa attgctatat cctgttaagt attaaaaaat atcctgatgc cgttcaacta
     1561 agtcatttgc agtccagcca gatgaatatt catcatcagt cggccttaaa taatctaaat
     1621 ttaacgtcgt atgacccggt aaactattcc ccaccgaaac gccctggtaa tgtaattgtt
     1681 tagcagcgtt acattgcgca caggctccac ttccacatgg aatgtattta cacctgtcaa
     1741 gaatacacgc tattttaccg tatatgttgc actca
//
LOCUS       DADXDL010000247         1761 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.255, whole genome shotgun sequence.
ACCESSION   DADXDL010000247 DADXDL010000000
VERSION     DADXDL010000247.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1761)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1761)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1761
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.255"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..804
                     /locus_tag="IRB70_004967"
     CDS             <1..804
                     /locus_tag="IRB70_004967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF945 domain-containing protein"
                     /protein_id="HBC0634756.1"
                     /translation="FGRYNSIRRERPLTDDELMQFVPSVFSGDKHESRSERYTYIPTI
                     NIINKLRDEGFQPFFACQSRVRDLGRREYSKHMLRLRREGHINGQEVPEIILLNSHDG
                     SSSYQMIPGIFRFVCTNGLVCGNNFGEIRVPHKGDIVGQVIEGAYEVLGVFDKVTDNM
                     EAMKEIHLNSDEQHLFGRAALMVRYEDENKTPVTPEQIITPRRREDKQNDLWTTWQRV
                     QENMIKGGLSGRSASGKNTRTRAITGIDGDIRINKALWVIAEQFRKWKS"
     gene            complement(1101..1703)
                     /locus_tag="IRB70_004968"
     CDS             complement(1101..1703)
                     /locus_tag="IRB70_004968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transglycosylase SLT domain-containing protein"
                     /protein_id="HBC0634757.1"
                     /translation="MVLLVVRTTNLLSLFVEWVKLFTDKVTRGGKMKKWMLAICLMFI
                     NEICQATDCFDLAGRDYKIDPDLLRAISWQESRYRVNAIGINPVTGYGSGLMQVDSQH
                     FNELARYGIKPEHLTTDPCMNIYTGAYYLAIAFKKWGVTWEAVGAYNAGFRKTERQNQ
                     RRLAYASDVYRIYTGIKSSKGIRLPATKKSLPEINSVQNN"
BASE COUNT          468 a          368 c          409 g          516 t
ORIGIN      
        1 tttggtcggt ataattccat ccgccgtgaa cgtcctttaa cggatgatga attaatgcag
       61 ttcgtgcctt cggtattttc cggtgataaa catgagtccc ggagtgaacg ttatacgtat
      121 attccaacaa tcaatatcat caataagtta cgtgatgaag gtttccagcc attctttgcc
      181 tgtcagagtc gggttcgtga tttgggacgt cgcgaataca gtaaacatat gttacgtctt
      241 cgcagggaag ggcatattaa cggacaggaa gttcctgaaa ttatcctgct taattcacat
      301 gatggttcat ccagttatca gatgatcccc ggaatttttc gttttgtctg cacaaatggc
      361 ctggtgtgcg gaaataattt tggcgaaatc cgcgttccac ataaaggtga tattgtcggg
      421 caggttatcg agggagcgta tgaagtgctc ggtgtctttg ataaggtcac tgataatatg
      481 gaggcgatga aagaaattca tcttaacagt gacgagcaac atttatttgg cagagctgca
      541 ctgatggtca ggtatgaaga tgaaaataaa acgccagtga cacctgaaca gataattact
      601 ccccgtcgtc gggaagacaa acagaacgat ctctggacaa cctggcagcg ggttcaggag
      661 aatatgataa aaggtggatt atcggggcga agtgcctccg ggaaaaatac caggacaaga
      721 gccattacag gtattgatgg tgatataaga atcaacaagg cgttatgggt gattgccgaa
      781 cagttcagaa agtggaagtc atgataatat aagtaaagcc ccgaaaaaat tttcggggct
      841 ttacttatat tatcattttt cggcattgct gtgtcgtctg atatacctca atttcatcaa
      901 ccggctttcc ggttgtctgt aaatattgtg cctgcgaaaa atggtctggc aggaggctgc
      961 gcagttaccg ggtatatata agatgggttc ccgcttcgcg gggcttcggc cagtcagtat
     1021 tgtcactcat atgatatttt tgtgtgtggc cttccatgcc gcttttgcgg cataaccggt
     1081 atctgacaat gtctgtaaga ttaattgttc tgcacgctgt taatttccgg aagtgatttc
     1141 ttcgtggccg gaagccggat acctttactg ctttttatcc cggtataaat ccggtaaaca
     1201 tctgatgcgt aggcaagacg tctctggttc tggcgttcgg ttttcctgaa tccggcattg
     1261 tatgcaccaa cggcctccca ggtgacgccc cattttttaa atgctattgc cagataataa
     1321 gcaccggtat aaatgttcat gcagggatct gttgtcagat gttctggctt aattccgtag
     1381 cgggccagtt cgttaaaatg ctgggaatct acctgcatca gtccgctgcc atatcccgtt
     1441 accggattaa taccgatggc attaacccgg taacgggatt cttgccatga tattgctctc
     1501 agtaaatcag gatctatttt gtaatcccgg cctgcaagat caaagcaatc agtggcttgg
     1561 cagatctcat ttataaacat caggcagatg gctaacatcc attttttcat ttttccacct
     1621 ctggtgactt tatccgtaaa taatttaacc cactccacaa aaaggctcaa caggttggtg
     1681 gttctcacca ccaaaagcac cacacactac gcaaaaacaa gtttttgctg atttgctact
     1741 tgaatcatta acttatgttt t
//
LOCUS       DADXDL010000248         1678 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.256, whole genome shotgun sequence.
ACCESSION   DADXDL010000248 DADXDL010000000
VERSION     DADXDL010000248.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1678)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1678)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1678
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.256"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..440)
                     /locus_tag="IRB70_004969"
     CDS             complement(<1..440)
                     /locus_tag="IRB70_004969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscU/YscU/HrcU family type III secretion system
                     export apparatus switch protein"
                     /protein_id="HBC0634758.1"
                     /translation="MANKTEKPTQKKLQDASKKGQILKSRDLTVSVIMLVGTLYLGYV
                     FDVHHIMSILEYILDHNAKPDIWDYFKAMGIGWLKTIIPFLLVCMFTTILVSWFQSKM
                     QLATEAIKFKFDSLNPVNGLKRIFGLKTVKEFVKAILYIIFFALA"
     gene            complement(449..1216)
                     /gene="sctT"
                     /locus_tag="IRB70_004970"
     CDS             complement(449..1216)
                     /gene="sctT"
                     /locus_tag="IRB70_004970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion system export apparatus
                     subunit SctT"
                     /protein_id="HBC0634759.1"
                     /translation="MGEAILYQLHSLLAATALGFCRLAPTFYLLPFFASGNIPTVVRH
                     PIIIVVSCALVQHYHYELSTLNEIDIALLAAREIIIGLFIACLLASPFWIFLAIGSFI
                     DNQRGATLSSTLDPATGVDTSELARLFNLFSAAVYLTNGGLNFILETLWQSYNLWPSG
                     NFNFPKLEPLFSYINNIMTHTIVYASPVIAVMLGGEAVLGLLARYASQLNAFAISLTV
                     KSALAFLILIIYFGPILAERVMPLSFFPEQLQLYIDK"
     gene            complement(1218..1478)
                     /locus_tag="IRB70_004971"
     CDS             complement(1218..1478)
                     /locus_tag="IRB70_004971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscS/YscS/HrcS family type III secretion system
                     export apparatus protein"
                     /protein_id="HBC0634760.1"
                     /translation="MDDIVFAGNRALYLILVMSAGPIAVATFVGLLVGLFQTVTQLQE
                     QTLPFGVKLLCVSICFFLMSGWYGEKLYSFGIEMLNLAFARG"
     gene            complement(1488..>1678)
                     /locus_tag="IRB70_004972"
     CDS             complement(1488..>1678)
                     /locus_tag="IRB70_004972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311752.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="EscR/YscR/HrcR family type III secretion system
                     export apparatus protein"
                     /protein_id="HBC0634761.1"
                     /translation="IYLPFVVVDLVISSVLLTLGMMMMSPVTISTPIKLILFVAMDGW
                     TMLSKGLILQYFDLSINP"
BASE COUNT          584 a          336 c          285 g          473 t
ORIGIN      
        1 gccaatgcaa aaaaaataat ataaagtatt gctttaacaa attcttttac ggtttttaag
       61 ccaaatatac gttttaagcc atttactgga tttaatgaat caaacttaaa cttaatagct
      121 tcagttgcta attgcatttt actttgaaac catgagacaa gtattgttgt aaacatgcaa
      181 accagcaaaa aaggaatgat cgttttcaac caacctatcc ccatagcttt aaaatagtcc
      241 caaatatccg gtttagcgtt atgatcaagg atgtattcaa gaatcgacat aatgtgatgc
      301 acatcaaata catatccgag atataaagta cccacaagca ttattacaga gactgttaag
      361 tctctacttt ttagaatttg ccctttttta gaagcatcct ggagtttctt ttgtgttggc
      421 ttttcagttt tatttgccat gaaacactct atttatcaat gtataattgc aattgttctg
      481 ggaaaaagga taacggcata actcgttcag ccagtattgg gccaaaataa ataattaata
      541 ttaaaaatgc cagcgcactt ttgacagtca gtgagatggc aaaagcattt agttgtgaag
      601 catagcgtgc cagcaatccc aggacagctt caccgcccag cataaccgca atcacggggc
      661 ttgcgtaaac gatagtatga gtcattatat tattaatata tgagaataaa ggctctaatt
      721 taggaaaatt aaaatttcct gaaggccata agttataact ttgccataga gtctccagaa
      781 taaagttcaa tccaccgtta gtaagataaa ctgctgcaga gaaaaggtta aataatcttg
      841 ctaattccga tgtatcgaca cctgtagccg gatccaaagt actacttaac gttgcaccac
      901 gttggttatc gataaagctg cctatagcaa ggaaaatcca aaatggggat gctaataagc
      961 aagcaataaa cagccctatg ataatttctc tggcagctaa caaagcgata tctatttcat
     1021 ttaaggtcga taattcatag tggtaatgct gaactaatgc acatgatacc actattatta
     1081 ttgggtgacg aactactgtt ggtatattcc cactggcgaa aaatggtaac aaatagaaag
     1141 ttggcgccaa tcggcaaaaa ccgagcgctg tagcagccag cagactatgc aactgataga
     1201 gtatcgcctc ccccatgcta tcctctcgcg aatgctaaat tcagcatttc aataccaaaa
     1261 gagtataatt tttcaccgta ccatccgctc attaaaaaaa agcaaatact tacgcataat
     1321 aatttgacgc caaatggcaa cgtctgttct tgcaactgtg ttaccgtttg aaaaagccct
     1381 accaataaac caacaaatgt cgcaactgca ataggtcctg cagacataac taaaatcaga
     1441 tacagcgccc tattccccgc aaaaacaatg tcgtccatat tttttcctca gggattaatg
     1501 gatagatcaa aatattgtaa aatgagtcct ttcgataaca ttgtccaacc gtccatcgcg
     1561 acaaacagaa ttaattttat cggtgtagat atggttaccg gactcatcat catcatacct
     1621 aacgttaaca gaacactgga tataaccaga tcaactacaa caaagggtaa atagatat
//
LOCUS       DADXDL010000249         1675 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.257, whole genome shotgun sequence.
ACCESSION   DADXDL010000249 DADXDL010000000
VERSION     DADXDL010000249.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1675
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.257"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..191
                     /locus_tag="IRB70_004973"
     CDS             <1..191
                     /locus_tag="IRB70_004973"
                     /EC_number="5.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032248255.1"
                     /note="capsular polysaccharide biosynthesis protein;
                     catalyzes the formation of D-mannose 6-phosphate from
                     alpha-D-mannose 1-phosphate; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="phosphomannomutase CpsG"
                     /protein_id="HBC0634762.1"
                     /translation="RAQYEPAAAHIDTTDGISIEYPEWRFNLRTSNTEPVVRLNVESR
                     ADTALMNAKTEEILALLK"
     gene            355..1521
                     /gene="ugd"
                     /locus_tag="IRB70_004974"
     CDS             355..1521
                     /gene="ugd"
                     /locus_tag="IRB70_004974"
                     /EC_number="1.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005227854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 6-dehydrogenase"
                     /protein_id="HBC0634763.1"
                     /translation="MKITISGTGYVGLSNGVLIAQNHEVVALDIVQAKVDMLNQKISP
                     IVDKEIQEYLAEKPLNFRATTDKHDAYRNADYVIIATPTDYDPKTNYFNTSTVEAVIR
                     DVTEINPNAVMIIKSTIPVGFTRDIKERLGIDNVIFSPEFLREGRALYDNLHPSRIVI
                     GERSARAERFADLLKEGAIKQDIPTLFTDSTEAEAIKLFANTYLALRVAYFNELDSYA
                     ESQGLNSKQIIEGVCLDPRIGNHYNNPSFGYGGYCLPKDTKQLLANYESVPNNIIAAI
                     VDANRTRKDFISDSILARKPKVVGVYRLIMKSGSDNFRASSIQGIMKRIKAKGIPVII
                     YEPVMQEDEFFNSRVVRDLDAFKQEADVIISNRMAEELADVVDKVYTRDLFGND"
BASE COUNT          446 a          389 c          405 g          435 t
ORIGIN      
        1 tccgggcaca gtatgagccg gcggccgcac acatcgacac aacggacggt atcagtattg
       61 aataccctga gtggcgcttt aacctgcgca cgtccaatac ggagccggtg gtgcgtctga
      121 acgtggagtc cagagcggat actgcgttaa tgaatgcaaa aaccgaagag attttagctc
      181 ttctcaagta atgcattatc cataatggaa gccataggat cagattttaa tcgtattatt
      241 gaccttatgg cttattcttg acatcccact ggtcaaagcg taaaaccgcc cacagtatta
      301 tttaaattcg tggctatccg ccattaccca gttaactgat taaagtgtaa tctcatgaaa
      361 attactattt ccggtacagg ttatgttggt ttatcgaacg gtgtcctgat tgcgcaaaac
      421 cacgaagtgg ttgccctgga tatcgtacag gccaaagtgg atatgcttaa ccagaagatc
      481 tctccgattg tggataaaga gattcaggaa tatctggcag aaaaaccgtt aaatttccgt
      541 gccaccacgg acaagcacga cgcctatcgt aatgccgact acgtgattat tgcgacgccg
      601 accgattatg atcccaaaac caactacttc aacacctcta cagtggaagc ggttattcgc
      661 gatgtcacag agatcaaccc gaacgcggtg atgatcatta aatcgaccat ccctgtgggg
      721 tttacccgcg acatcaaaga acgtttaggg atagataatg ttattttctc tcctgagttc
      781 ctgcgtgaag gccgtgcgct gtacgacaac ctgcacccgt cgcgcattgt tattggtgag
      841 cgctctgcgc gtgctgaacg tttcgcagac ctgttgaaag aaggcgcgat taagcaggat
      901 atcccgaccc tgtttaccga ctccactgaa gcggaagcga tcaaactgtt cgcgaacacc
      961 tatctggcgc tgcgcgttgc ctatttcaac gagctcgaca gctatgctga aagccagggg
     1021 ctgaacagca agcagattat cgaaggggta tgcctggatc cgcgtatcgg caaccactat
     1081 aacaacccgt cctttggcta tggcggctac tgcctgccga aagataccaa gcagctactg
     1141 gcgaactacg aatcggtccc gaataatatc attgccgcta ttgtggacgc caaccgtacc
     1201 cgtaaggact ttatttctga ttccatcctc gctcgtaagc cgaaagtggt gggtgtatat
     1261 cgcctgatca tgaagagtgg ttcggacaat ttccgcgcct cttctatcca gggcatcatg
     1321 aagcgcatca aggcgaaagg tattccggtc attatctatg aaccggtgat gcaggaagat
     1381 gagttcttca actcacgcgt cgtgcgcgac ctggatgcct tcaaacaaga ggcggatgtg
     1441 atcatctcta accgtatggc ggaagagttg gcggatgtgg tggacaaggt ttacacccgc
     1501 gatctgtttg gtaatgatta ggatttataa cctttggctg gatgagaata tctccagcca
     1561 aattttatat gaaattggat ttcattgatg ttaattaact tgtggaaatg gttatccagt
     1621 tagttattta cggttagtga gtttttctgg tgatataaac aaagtttgta aaaca
//
LOCUS       DADXDL010000250         1663 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.258, whole genome shotgun sequence.
ACCESSION   DADXDL010000250 DADXDL010000000
VERSION     DADXDL010000250.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1663)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1663)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1663
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.258"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            162..>1663
                     /locus_tag="IRB70_004975"
     CDS             162..>1663
                     /locus_tag="IRB70_004975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004119118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BCCT family transporter"
                     /protein_id="HBC0634764.1"
                     /translation="MSENDTIPKKSTSQINKAVFFTSALLIFLLVAFAAVFPDVADKN
                     FKLLQQQIFTNASWFYILAVALILLSVTFLGLSRYGDIKLGPDHAQPDFSYHSWFAML
                     FSAGMGIGLMFFGVAEPVMHYLSPPVGTPETVAAAKEAMRLTFFHWGLHAWAIYAIVA
                     LILAFFSYRHGLPLTLRSALYPIIGDRIYGPVGHAVDIFAVIGTVFGVATSLGYGVLQ
                     VNAGLNHLFGVPINETVQVILIVVITGLATISVVSGLDKGIRILSELNLGLALLLLAL
                     VLCLGPTVLLLKSFVENTGGYLSELVSKTFNLYAYEPKSSNWLGGWTLLYWGWWLSWS
                     PFVGMFIARVSRGRTIREFVTGVLFVPAGFTLMWMTVFGNSAIYLIMNQGATDLANTV
                     QQDVALALFNFLEHFPFSSVLSFIAMAMVIVFFVTSADSGAMVVDTLASGGVANTPVW
                     QRIFWASLMGIVAIALLLAGGLSALQTVTIASALPFSVILLISIYGLLKA"
BASE COUNT          341 a          399 c          429 g          494 t
ORIGIN      
        1 ctgcttaaaa aaagaacaaa tggtagtgtc cgctattgcc agtacacctc aacattccac
       61 catgcattcc gattaacgcc gcatagccag ttgaactttg ctactttgtg agaggtagta
      121 ccttctatcc agtgcgaatt taattaatgg aataaatgat tatgagtgaa aatgatacaa
      181 tcccaaagaa gtctacaagt cagattaaca aagcggtatt ctttacatct gctttgctaa
      241 ttttccttct tgtcgccttt gccgccgtat tcccggatgt cgccgacaaa aattttaaac
      301 tacttcagca acaaatcttc acgaatgcca gctggttcta catccttgct gtggccctga
      361 ttttactgag tgtcacgttc cttggactct cacgctacgg tgatatcaag ctgggcccgg
      421 accatgcgca gcctgatttc agctaccact cctggtttgc gatgcttttt tcggcaggga
      481 tggggatcgg cctgatgttc tttggcgttg ccgaacctgt aatgcattat ctttcgccac
      541 ccgttggcac tccagaaacc gttgcggcag ctaaggaagc aatgcgtctg acctttttcc
      601 actggggact gcacgcatgg gcaatttatg ccattgtggc gctgattctg gcgttcttca
      661 gttaccgtca cggtctgcct ttaactctgc gctccgcact ctatcccatt attggcgatc
      721 gcatatacgg acctgtagga catgcggttg atattttcgc tgttataggc acggtctttg
      781 gcgttgcgac atcactgggt tacggtgttt tgcaggtgaa tgccggtttg aaccatcttt
      841 tcggggtgcc catcaatgaa acggtgcagg taattctgat cgtggtcatc acggggttag
      901 cgacgatttc agtggtgtcc ggtctggata agggaatacg tatcctgtct gaactcaatc
      961 tgggtctggc tttgttgctc ctggcgctgg tcctgtgtct gggaccaacc gtgcttctgc
     1021 tgaagtcatt tgtggaaaat acgggcggtt atctttcgga actggtgagt aaaacgttca
     1081 acctttacgc gtatgagccc aagtcgagca actggctggg gggctggaca ttactgtact
     1141 ggggatggtg gctttcatgg tcgccgtttg tggggatgtt catcgcacgg gtctcccgcg
     1201 ggcgaaccat tcgcgagttt gtcaccggcg tgctgtttgt tcccgcgggt tttacgctaa
     1261 tgtggatgac ggtgtttggt aacagcgcga tctatctcat tatgaaccag ggggccacag
     1321 acctcgccaa tactgttcag caggatgtgg cgctggccct gtttaatttc ctggagcatt
     1381 tcccgttctc ttctgtgctg tcattcattg caatggcgat ggtcatcgtc ttctttgtaa
     1441 cgtctgctga ttcgggggca atggttgtgg atactctggc atcaggtgga gtggcaaaca
     1501 cacccgtctg gcagcgaata ttctgggcct cgctcatggg cattgttgca attgcgcttc
     1561 tccttgccgg agggctaagt gcgctgcaaa cggtgacaat agcgagtgca ttgcccttct
     1621 cagtgatctt actaatatct atatacggac ttttaaaagc ttt
//
LOCUS       DADXDL010000251         1654 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.259, whole genome shotgun sequence.
ACCESSION   DADXDL010000251 DADXDL010000000
VERSION     DADXDL010000251.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1654)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1654)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1654
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.259"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(3..887)
                     /locus_tag="IRB70_004976"
     CDS             complement(3..887)
                     /locus_tag="IRB70_004976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001557377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosome-binding GTPase"
                     /protein_id="HBC0634765.1"
                     /translation="MPFSNSSLSAQVKSYLTFLPEEIRQKILEHLHGVIHYEPVIGIM
                     GKSGTGKSSLCNAIFQSRICATHPLNGCTRQAHRLTLQIGERRMTLVDLPGIGETPQH
                     DQEYRELYRQLLPELDLIIWILRADERAYAADIAMHQFLLNEGADPSRFLFVLSHADR
                     VFPAEEWNATEKCPSRHQELSLATVTARVATLFPSSFPVLPVAAPVGWNLPAFVSLMI
                     HALPPQATSAVYSHIRGENRSEQAQKHAQQTFGDAIGKSFDDAVARFTFPVWMLQLLR
                     KARDRIIRLLETLWDRLF"
     gene            988..>1654
                     /locus_tag="IRB70_004977"
     CDS             988..>1654
                     /locus_tag="IRB70_004977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001702852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634766.1"
                     /translation="MAKNKGICRNKKCSNPVSEFDEANALRLCDDHYKLWKRNKENRR
                     VRNICRIISRYDKSLDWEIFYRVRDAAKNKTGKRIIEDAKILHQWRASKQVRKSFHKG
                     VLRSREWLNTQELLSRKHISVTGELFKFYIKDIIRLYCYKFLYSREYLNENAYKKRYQ
                     RDIHPRKVNVPILQLEVAWINNNCRSSDSSTDIIILPRMIRRMVVFNYTKINKQLEKV
                     LGGI"
BASE COUNT          508 a          320 c          422 g          404 t
ORIGIN      
        1 tgtcagaaca gacgatccca cagtgtttct agcaggcgga taatgcggtc ccgggcttta
       61 cgcagaagct gtaacatcca gaccggaaaa gtgaaccggg caacggcgtc gtcaaaactt
      121 ttcccgatgg cgtcaccaaa agtctgttgt gcgtgtttct gggcctgttc agagcggttt
      181 tccccccgga tatgtgaata aaccgcactg gttgcctgcg gtggcagggc gtggatcatc
      241 agcgacacaa acgccggaag attccagccg acaggcgcag caacggggag taccggaaat
      301 gatgacggga acagggttgc caccctggct gtaacagttg ccagtgagag ttcctggtga
      361 cgggatgggc atttttctgt ggcattccat tcttcagcag gaaacacgcg atcggcatgg
      421 ctgagaacaa acagaaaacg cgagggatct gcaccttcat tcagtaaaaa ctgatgcatg
      481 gcaatatcgg cagcatacgc acgttcatca gcccgcagga tccagataat cagatccagt
      541 tccggcagta actgacggta aagctcccgg tattcctgat catgctgcgg tgtctcacca
      601 atgccgggca gatcgaccag cgtcattctg cgttcaccaa tctgcagggt gaggcgatga
      661 gcctggcggg tgcagccgtt caggggatgc gtggcgcaga tacgggactg aaaaatggca
      721 ttacacagac tgcttttgcc ggtgccggat ttacccataa tgccaatcac gggctcgtaa
      781 tgaataacac cgtggagatg ttcaaggatt ttctggcgaa tttcttcagg aagaaacgtc
      841 agatatgatt tcacttgcgc ggagagggaa gaattgctga atggcatacc ggtatcctgt
      901 tgatttcact gaaccggatc acactaatcc ggtttatcat tcaggtaata tgggtgtgaa
      961 aatttttcca ttgacgggaa gaagagtatg gctaaaaaca aaggtatctg tcggaataaa
     1021 aaatgcagta atcctgtttc agaatttgat gaggcaaatg ccttaaggtt atgcgatgat
     1081 cattataagc tatggaagcg aaataaagag aatcgtcggg tcaggaatat ttgtcgtata
     1141 attagtagat atgacaaaag tctggactgg gagatatttt atagagtaag agatgctgca
     1201 aaaaataaaa cgggaaagag aattattgag gacgcaaaaa tattacatca atggcgtgct
     1261 tcaaagcaag taagaaaaag ttttcacaag ggtgtgcttc ggtcacggga atggcttaat
     1321 acacaggagt tactgagcag aaaacatata tctgttacag gtgaactatt taaattttac
     1381 ataaaagata ttatcagatt atattgctat aagtttctct acagcagaga atatcttaat
     1441 gaaaacgcat acaaaaaacg atatcagaga gatattcacc ccagaaaagt taatgttccg
     1501 atactgcaac ttgaagttgc atggataaat aataattgcc gctcaagtga ttcaagcact
     1561 gatattatta tccttccgag gatgataaga agaatggttg tatttaatta tacgaagata
     1621 aataaacaat tagagaaagt gttggggggg atag
//
LOCUS       DADXDL010000252         1630 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.260, whole genome shotgun sequence.
ACCESSION   DADXDL010000252 DADXDL010000000
VERSION     DADXDL010000252.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1630)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1630)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1630
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.260"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1100
                     /gene="ompC"
                     /locus_tag="IRB70_004978"
     CDS             <1..1100
                     /gene="ompC"
                     /locus_tag="IRB70_004978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="porin OmpC"
                     /protein_id="HBC0634767.1"
                     /translation="KLKIVAVVVTGLLAANVAHAAEVYNKDGNKLDLYGKVTALRYFT
                     DDKRDDGDKTYARLGFKGETQINDQMIGFGHWEYDFKGYNDEANGSRGNKTRLAYAGL
                     KISEFGSLDYGRNYGVGYDIGSWTDMLPEFGGDTWSQKDVFMTYRTTGVATYRNYDFF
                     GLIEGLNFAAQYQGKNERTDNGHLYGADYTRANGDGFGISSTYVYDGFGIGAVYTKSD
                     RTNAQERAAANPLNASGKNAELWATGIKYDANNIYFAANYAETLNMTTYGDGYISNKA
                     QSFEVVTQYQFDFGLRPSLAYLKSKGRDLGRYGDQDMIEYIDVGATYFFNKNMSTYVD
                     YKINLIDESDFTRAVDIRTDNIVATGITYQF"
     gene            1264..>1630
                     /locus_tag="IRB70_004979"
     CDS             1264..>1630
                     /locus_tag="IRB70_004979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine-rich repeat domain-containing protein"
                     /protein_id="HBC0634768.1"
                     /translation="MIMTNINTACVKNNASYQLNNALPNKETISSNFCERLAQWGNKS
                     LNNGEERAIAVERIKEAYNSNMASLDLSYLDLSELPPIPSTVNTLNLENNCLTCLDFT
                     DNASLVNINLSFNKIKTITF"
BASE COUNT          482 a          339 c          339 g          470 t
ORIGIN      
        1 tgaaattaaa aatagttgcg gtggttgtaa ctggtttgtt agctgcgaac gtagcacacg
       61 ctgccgaagt ctataacaag gatggtaata aactcgacct ttatggcaag gttaccgctc
      121 tacgttattt tactgatgat aagcgtgacg atggtgataa aacttatgcc cgtctcggct
      181 ttaaaggaga aacgcaaatc aatgatcaaa tgattggttt tggtcactgg gaatatgatt
      241 ttaaaggcta taacgatgaa gccaacggct cgcgcggtaa caagacccgt ctggcctatg
      301 caggtttaaa aattagtgaa tttggctctc tggactatgg tcgtaactac ggtgtcggct
      361 atgacattgg ttcatggacc gatatgttgc cagaatttgg tggcgatacc tggagtcaga
      421 aagatgtctt catgacatac cgtactaccg gtgtggcaac ctatcgcaac tacgatttct
      481 tcggcttaat tgaaggtctg aactttgccg cgcaatatca aggcaaaaat gaacgcactg
      541 acaatggtca tctttatggt gctgactata cgcgtgccaa tggtgacggt ttcggtatct
      601 cctcaactta tgtttatgat ggctttggta tcggtgcggt gtataccaaa tccgatcgga
      661 caaatgcgca ggaaagagcc gctgctaatc ctctcaatgc ctccggtaag aatgcagaac
      721 tgtgggctac aggtataaaa tatgatgcca acaacatcta ctttgcagct aattacgctg
      781 aaacattaaa catgaccacc tatggcgatg gttatatctc taacaaagca caaagttttg
      841 aagtagtgac acaatatcaa ttcgacttcg gcttgcgtcc atcactcgct tacctgaaat
      901 cgaaaggcag agatctgggc cgctacggcg accaggacat gattgagtat atcgacgttg
      961 gtgcgacgta tttcttcaac aaaaatatgt cgacctatgt tgattataaa atcaacctga
     1021 ttgatgaaag cgactttacc cgtgccgtag atattcgcac cgataacatc gtcgcaacgg
     1081 gaattaccta tcagttctaa catcctctcc tgaccagccc ttctctgggc tggtttttga
     1141 tttaagtgct gctgtatgac tccttaagta aaaatgagca atttttgata tttctggtca
     1201 ttcacctcaa ttaatattat tccataccct ccggggacat cttactataa tatttattga
     1261 tgagtgatta tgaccaatat taatacagct tgtgtaaaaa ataatgccag ttatcaatta
     1321 aataacgcat tacctaacaa agaaaccatc tccagcaatt tttgtgaacg actggcacaa
     1381 tggggtaata agtcgcttaa taatggtgaa gaaagagcaa ttgccgtgga gcgaattaaa
     1441 gaagcttaca attcgaacat ggcatctctt gatttgtcat atcttgattt gagtgagtta
     1501 ccccctatcc cctcgacagt taacacgtta aatctggaaa acaattgtct cacttgtctt
     1561 gactttactg acaatgccag cctcgtcaat atcaacctca gctttaataa aattaaaacg
     1621 ataacctttc
//
LOCUS       DADXDL010000253         1626 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.261, whole genome shotgun sequence.
ACCESSION   DADXDL010000253 DADXDL010000000
VERSION     DADXDL010000253.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1626
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.261"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(45..224)
                     /locus_tag="IRB70_004980"
     CDS             complement(45..224)
                     /locus_tag="IRB70_004980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GhoT/OrtT family toxin"
                     /protein_id="HBC0634769.1"
                     /translation="MINKLLLAYLIGLVVTSTLIFIFSEEKVTYRLFAAAITGLTWPL
                     SLIPSIISLMIRKSD"
     gene            complement(291..>1626)
                     /locus_tag="IRB70_004981"
     CDS             complement(291..>1626)
                     /locus_tag="IRB70_004981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001613747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634770.1"
                     /translation="LTLTEKPWGTFILASTFEDDKTAAETHYDAVWLRDSLWGYMALV
                     SDQGNSVAAKKVLLTLWDYMSTPDQIKRMQDVISNPKRLDGIPGQMNAVHIRFDSNSP
                     VMADVQEEGKPQLWNHKQNDALGLYLDLLIQAIDTGTINAEDWQKGDRLKSVALLIAY
                     LDEANFYIMEDSGAWEEDARLNTSSVALVTSGLERLSNLLSKKDSVFVSDLLREAKAN
                     ELDATFSTTRLNHLIDKGYERITLQLDLGGESPGYLEKDKHYREADAALLNVIYPANL
                     SKINTRRKEQVLKIVKKLAGPYGIKRYEKDNYQSANFWFNDIKTDTDQNSHAKREMSF
                     IPSTEAEWFFDSWYAKSAAIVYKESRKEEYLNDSVQFMNRSLAQITGENMIGANGRSV
                     PEMALPESYNYIHKSGTLHEAPSPIIPLNWSKASMTLMLKEMSNLINDEGNK"
BASE COUNT          424 a          357 c          299 g          546 t
ORIGIN      
        1 ctttttcgat tctatttttc ttaatcgttc atataatttt cttgttagtc ggatttacga
       61 atcatgagac ttatgatgga tggaatgagg ctaagcggcc aggtcaaccc tgtaattgct
      121 gcagcaaaca accgatatgt tactttttct tccgagaaga taaatattaa ggtcgatgtc
      181 acaaccagac ctatcaggta agctaacagt aatttattga tcacttttac ctcccctttc
      241 gatttctctt tgagcggtcc ttttaatcca ggaccgcctc attatgaaaa ctatttattt
      301 ccctcatcat tgataaggtt ggacatctct ttcaacatga gagtcattga agctttcgac
      361 caatttagcg gaatgatagg gcttggcgct tcatgcaaag ttcccgactt gtggatatag
      421 ttatagcttt cgggaagtgc catttcaggt acactcctgc catttgcacc aatcatattc
      481 tcgcctgtta tttgggccaa tgatctattc ataaattgca cagagtcatt caaatactct
      541 tcttttcttg attctttata aacaattgct gctgattttg cataccatga gtcaaaaaac
      601 cattctgctt ctgttgatgg aatgaagctc atttctcttt tcgcatgtga attttgatcg
      661 gtatcggttt taatatcatt gaaccaaaaa tttgccgact gataattatc cttctcgtat
      721 ctttttatac catacggacc tgctagtttt ttaactattt ttagaacttg ctcttttctt
      781 ctggtattta tctttgaaag atttgcagga taaataacat taagtaaagc cgcatcggct
      841 tctctgtaat gtttatcttt ttccagataa cctggggatt ctccccctaa atcaagctgt
      901 aacgttattc tttcataacc tttatctatg aggtggttca acctcgttgt tgaaaaagtt
      961 gcatccagtt cattggcttt agcttcgcgt agtaaatcag agacaaaaac agagtctttc
     1021 ttcgagagta ggtttgacaa acgttccagt ccagaggtca ccagtgcaac ggaagatgtg
     1081 tttaatcggg catcttcttc ccacgctccg gaatcttcca taatatagaa attggcttca
     1141 tccagataag caatcagcag cgcaaccgat tttaatcggt cacctttttg ccaatcttca
     1201 gcgttaatag taccagtgtc gattgcttgt ataaggagat caagataaag acctaacgca
     1261 tcattttgtt tatggttcca cagctgcggc ttgccttctt cctgcacatc tgccatcacg
     1321 ggggagttgc tgtcaaatcg gatatgtaca gcattcattt gcccaggaat accatccagt
     1381 cgttttgggt tgctaatgac gtcctgcatc cgcttaatct ggtcgggcgt agacatataa
     1441 tcccacagag tgagcagaac cttttttgcg gctacactat ttccctgatc tgatactaat
     1501 gccatatagc cccataaact atccctcagc cagacagcat catagtgggt ttctgccgct
     1561 gttttgtcat cttcgaaagt agaagcaaga ataaatgttc cccagggttt ctccgtcaac
     1621 gttaac
//
LOCUS       DADXDL010000254         1588 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.262, whole genome shotgun sequence.
ACCESSION   DADXDL010000254 DADXDL010000000
VERSION     DADXDL010000254.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1588)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1588)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1588
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.262"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     repeat_region   207..1519
                     /inference="COORDINATES: alignment:crt:1.2"
                     /inference="COORDINATES: alignment:pilercr:v1.02"
                     /rpt_family="CRISPR"
                     /rpt_type=direct
                     /rpt_unit_range=270..297
                     /rpt_unit_seq="ggtttatccccgctggcgcggggaacac"
BASE COUNT          366 a          396 c          435 g          391 t
ORIGIN      
        1 tattaaaaaa aataatatat tgaaatttct taacggttta aggattatac aaataacact
       61 ttgattaaat ttgatttttt gtatcgataa ttgtgaactt atctggcatg gagaactatt
      121 ttgaacatga ggtgttatgt ggatatgttg cttattacaa gtacagctaa tataaaaact
      181 tgagaaagag ataacgggtt atatggtggt tcatccccgc tggcgcgggg aacacgtcct
      241 gtttttgacc ggcggtaaat gttgcctgcg gtttatcccc gctggcgcgg ggaacacaat
      301 atccgttcct cgctctgcgt tttcgttgac ggtttatccc cgctggcgcg gggaacacgg
      361 tcgggtattt cattatgcat cctgaactaa cggtttatcc ccgctggcgc ggggaacact
      421 atgcgcttgc tgctgcgttg atgtacgcgg ccggtttatc cccgctggcg cggggaacac
      481 ttaactacct gaacaccggg aagactccgg accggtttat ccccgctggc gcggggaaca
      541 cgattcaatg tccgacgcat ccaagtaaat attcggttta tccccgctgg cgcggggaac
      601 acggatgagc agggagcaac aaaagtagcc ggaatggttt atccccgctg gcgcggggaa
      661 cacccataca ttaacacggt gtggccacat ttcaacggtt tatccccgct ggcgcgggga
      721 acacgcgcgg ccgcgatatc gttagcactg gctcccgcgg tttatccccg ctggcgcggg
      781 gaacaccaaa acacctgaac gttgagatag ggctaaatcg gtttatcccc gctggcgcgg
      841 ggaacacgtt gtcgtattcc ttagaaatct gatgccagcc cggtttatcc ccgctggcgc
      901 ggggaacact gactgaccgg gaaaagaaaa cacctggcga acggtttatc cccgctggcg
      961 cggggaacac aatttttcca gtggtgtcgt tgtaattaag gacggtttat ccccgctggc
     1021 gcggggaaca caggttaaag aggcgcgccg ggcgctggct gggcggttta tccccgctgg
     1081 cgcggggaac acatccgtta attattgaga gagctatcag ctatcggttt atccccgctg
     1141 gcgcggggaa cactctaatt gcgctttgat aaatggagtt aaagccggtt tatccccgct
     1201 ggcgcgggga acacgaattc ggaatcacat taaaagggaa cccgataggt ttatccccgc
     1261 tggcgcgggg aacacccagg tcccatttgt cgatcggcag cgccattcgg tttatccccg
     1321 ctggcgcggg gaacactgtt aattcagcaa gttgagattg tgtcagtccg gtttatcccc
     1381 gctggcgcgg ggaacacaag agaacagctt atatctgatg ccggtttgcc ggtttatccc
     1441 cgctggcgcg gggaacacac accggcgaga tcgtattttt tgccgctgag cggtttatcc
     1501 ccgctggcgc ggggaacact ctaaacataa cctattatta attaatgatt ttttaagcca
     1561 gtcacaatct accaacttta tagtatca
//
LOCUS       DADXDL010000255         1579 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.263, whole genome shotgun sequence.
ACCESSION   DADXDL010000255 DADXDL010000000
VERSION     DADXDL010000255.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1579)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1579)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1579
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.263"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            6..158
                     /locus_tag="IRB70_004982"
     CDS             6..158
                     /locus_tag="IRB70_004982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001435887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein A"
                     /protein_id="HBC0634771.1"
                     /translation="MTKRASFKEVKVFLEPKYKAMLMQMCNEDGLTQAEVLTALIKSE
                     AQKRCM"
     gene            264..398
                     /locus_tag="IRB70_004983"
                     /pseudo
     CDS             264..398
                     /locus_tag="IRB70_004983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012615301.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="protein CopA/IncA"
     gene            395..469
                     /gene="tap"
                     /locus_tag="IRB70_004984"
     CDS             395..469
                     /gene="tap"
                     /locus_tag="IRB70_004984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001375168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepA leader peptide Tap"
                     /protein_id="HBC0634772.1"
                     /translation="MTGKVQDFFLCSLLLCNISAGWCD"
     gene            462..1319
                     /gene="repA"
                     /locus_tag="IRB70_004985"
     CDS             462..1319
                     /gene="repA"
                     /locus_tag="IRB70_004985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="incFII family plasmid replication initiator
                     RepA"
                     /protein_id="HBC0634773.1"
                     /translation="MTDLHQTYYRQVKNPNPVFTPREGAGTLKFCEKLMEKAVGFSSR
                     FDFAIHVAHARSRGLRRRMPPVLRRRAIDALLQGLCFHYDPLANRVQCSITTLAIECG
                     LATESGAGKLSITRATRALTFLSELGLITYQTEYDPLIGCYIPTDITFTLALFAALDV
                     SEDAVAAARRSRVVWENKQRKKQGLDTLGMDELIAKAWRFVRERFRSYQTELKSRGIK
                     RARARRDANRKRQDIVTLVKRQLTREISEGRFTANREAVKREVERRVKERMILSRNRN
                     YSRLATASP"
BASE COUNT          404 a          401 c          422 g          352 t
ORIGIN      
        1 cgttcgtgac aaaaagagct tcgttcaagg aagtaaaagt atttctcgaa ccaaagtata
       61 aggccatgct catgcaaatg tgtaatgaag atggcctgac ccaggctgaa gttctgaccg
      121 cactgataaa aagtgaagcg caaaaacgat gcatgtgatg atgggcttac attctgagtg
      181 ttcagaagat tagtgctaga ttactgatcg tttaaggaat tttgtggctg gccacgccgt
      241 aaggtggcag ggaactggtt ctgatgtgga tctacaggag ccagaaaagc aaaaaccccg
      301 ataatcttca ccaggtttgg cgactaagag aagattaccg gggctaacaa gaaactgcat
      361 agaagctgtt gctctatgcg gggagtatag ttatatgacc ggaaaagttc aagacttctt
      421 tctgtgctca ctccttctgt gcaacataag tgcaggatgg tgtgactgat cttcaccaaa
      481 cgtattaccg ccaggtaaag aacccgaatc cggtgttcac accccgtgaa ggtgccggaa
      541 cgttgaagtt ctgcgaaaaa ctgatggaaa aagcggtggg cttcagctcc cgttttgatt
      601 tcgctattca tgtggcgcat gcccgttcgc gtggtctgcg tcgacgcatg ccaccggtgc
      661 tgcgtcgacg ggctattgat gcgctgctgc aggggctgtg tttccattat gacccgctgg
      721 ccaaccgcgt ccagtgttcc atcaccacgc tggccattga gtgcggactg gcgacagagt
      781 ccggtgcagg aaaactctcc atcacccggg ccacccgggc cctgacgttc ctgtcagagc
      841 tgggactgat tacttaccag acggaatatg acccgcttat cgggtgctac attccgaccg
      901 atatcacgtt cacactggcg ctgtttgccg cccttgatgt gtctgaggat gcagtggcag
      961 ctgcgcgccg cagccgtgtg gtatgggaaa acaaacagcg caaaaagcag gggctggata
     1021 ccctgggtat ggatgaactg atagcgaaag cctggcgttt tgtgcgtgag cgtttccgca
     1081 gttaccaaac agagcttaag tcccggggaa taaagcgtgc ccgtgcgcgt cgtgatgcga
     1141 acaggaaacg tcaggatatc gtcaccctgg tgaaacgaca gctgacgcgt gaaatctcgg
     1201 aagggcgctt cactgccaat cgtgaggcgg taaaacgcga agtggagcgt cgtgtgaagg
     1261 agcgcatgat tctgtcacgt aaccgcaatt acagccgcct ggccacagct tccccctgaa
     1321 agtgacctcc tctgaataat tcggcacgcg ccggaggcat tcgcacgcct gaagcccgcc
     1381 agtgcacaaa aaatcagcac cacatacaaa aaaacaacct catcatccac cttcaggtgc
     1441 atccggtccc ccttgttttt gatacaaaac acgcctcaca gacgggtaat tttgcttatc
     1501 cacattaaac tgcaagggac ttccccataa ggttacaatc gttaatgtca taaagcgcca
     1561 gccgtcagcc ctacagggt
//
LOCUS       DADXDL010000256         1575 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.264, whole genome shotgun sequence.
ACCESSION   DADXDL010000256 DADXDL010000000
VERSION     DADXDL010000256.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1575
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.264"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..356)
                     /locus_tag="IRB70_004986"
     CDS             complement(<1..356)
                     /locus_tag="IRB70_004986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBC0634774.1"
                     /translation="MLQISHLYADYGGKPALEDINLTLESGELLVVLGPSGCGKTTLL
                     NLIAGFVPYQHGSIQLAGKGIQGPGAERGVVFQNEGLLPWRNVQDNVAFGLQLAGVEK
                     MQRLEIAHQMLKKVGL"
     gene            complement(369..1331)
                     /gene="tauA"
                     /locus_tag="IRB70_004987"
     CDS             complement(369..1331)
                     /gene="tauA"
                     /locus_tag="IRB70_004987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_414899.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="taurine ABC transporter substrate-binding
                     protein"
                     /protein_id="HBC0634775.1"
                     /translation="MAISSRNTLLAALAFIAFQAQAVNVTVAYQTSAEPAKVAQADNT
                     FAKESGATVDWRKFDSGASIVRALASGDVQIGNLGSSPLAVATSQQVPIEVFLLASKL
                     GNSEALVVKKTISKPEDLIGKRIAVPFISTTHYSLLAALKHWGIKPGQVEIVNLQPPA
                     IIAAWQRGDIDGAYVWAPAVNAMEKDGKVLTDSEQVGQWGAPTLDVWVVRKDFAEKHP
                     EVVKAFAKSAIDAQQPYIANPDVWLKQPENISKLARLSGVPEGDVPGLVKGNTYLTQQ
                     QQTAELTGPVNKAIIDTAQFLKDQGKVPAVANDYSQYVTSRFVQ"
BASE COUNT          350 a          441 c          371 g          413 t
ORIGIN      
        1 tccaggccga cttttttcag catctggtgc gcgatttcca gtcgctgcat tttctctacg
       61 cctgccagtt gcaggccgaa tgccacgttg tcctgtacat tgcgccacgg tagtagccct
      121 tcattctgaa aaactacgcc acgctctgcc cccggtccct gaataccctt acccgccagt
      181 tgaatgctgc catgctgata aggcacaaaa ccggcaatca aattcagcaa cgtagttttg
      241 ccgcagccag acggccccag aactaccaga agctcgccgc tttccagcgt caggttgata
      301 tcttccagtg ccggtttgcc gccataatcg gcgtaaagat gagagatttg cagcatctgc
      361 gcctcctttt attgcacgaa gcgcgaggtc acgtactggc tgtaatcatt cgccacggca
      421 gggactttgc cctgatcttt caaaaactgc gcggtatcga tgatcgcttt attcaccggt
      481 ccggtcagtt ctgccgtttg ttgctgctgc gtcagatagg tattcccctt caccagcccc
      541 ggaacgtcac cttcaggcac gccgcttaaa cgcgccagtt tgctgatgtt ttccggctgt
      601 ttcagccaca cgtctgggtt agcaatgtac ggttgctgag catcgatggc gcttttggcg
      661 aacgctttca cgacctctgg atgtttctcg gcaaaatctt tccgcacgac ccagacgtcc
      721 agtgtcggcg cgccccactg cccgacctgt tcagaatcgg tcagcacctt gccatctttt
      781 tccatggcgt taaccgccgg tgcccagaca taagcaccat caatgtctcc ccgctgccat
      841 gcggcgataa tcgcgggcgg ctgcaggttc acaatctcca cttgcccggg tttaataccc
      901 cagtgtttca gcgccgccag caggctgtag tgggtggtgg agataaacgg tacggcgatg
      961 cgtttaccaa tcaagtcttc cggtttactg atagttttct ttaccaccag cgcttcggag
     1021 ttacccagtt ttgacgccag caagaagact tcaatcggca cctgttggct ggttgcaacc
     1081 gctaacgggc tggaaccgag gttgccgatt tgcacgtcgc ctgaagccag cgcccgcacg
     1141 atgctggctc cgctgtcaaa cttacgccag tccacggttg ctccgctttc tttagcaaag
     1201 gtgttgtcgg cctgagccac tttcgccggt tcggctgagg tttgatacgc cacggtgacg
     1261 ttcaccgcct gtgcctgaaa agcgatgaat gccagtgcgg caagaagtgt gttacgcgat
     1321 gaaattgcca tgattgtctg ctcccctgtc ttgttatggg agcagtattc aggaataaaa
     1381 acattcatta aaagaattag tcgttatcgc acagatgatt ttattcttag caaaaaaacg
     1441 gcaaaggaaa gattaaatat gcaattactc cgttctaaca attgggaaaa ttactacact
     1501 tcattttagt gatgcataaa caaccacatt acgagattta ttacttcatt atttctatca
     1561 atatcaatac atata
//
LOCUS       DADXDL010000257         1566 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.265, whole genome shotgun sequence.
ACCESSION   DADXDL010000257 DADXDL010000000
VERSION     DADXDL010000257.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1566)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1566)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1566
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.265"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(1..692)
                     /locus_tag="IRB70_004988"
                     /pseudo
     CDS             complement(1..692)
                     /locus_tag="IRB70_004988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308756.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RHS repeat protein"
     gene            complement(738..1058)
                     /locus_tag="IRB70_004989"
     CDS             complement(738..1058)
                     /locus_tag="IRB70_004989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000873948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634776.1"
                     /translation="MYYFLFRAIWLALSLLILFFSMHRLSLLDSTRDVSELISLMSYG
                     MMVICFPTGIVFFIALIFIGTVSDIIGVRIDSKYIMAIIIWLYFLSGGYVQWFVLSKR
                     IINK"
     gene            complement(1063..1482)
                     /locus_tag="IRB70_004990"
     CDS             complement(1063..1482)
                     /locus_tag="IRB70_004990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001466636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634777.1"
                     /translation="MGGTGERSGPDIWGNPFYHQYLCVPDGKGDYTCGGQDQRGESKG
                     DGLWGPGKASNDTKEAAGRCDLVETDNSCVENCLKGKFKEVRPRYSVLPDIFTPINLG
                     LFKNCQDWSNDSLETCKMKCSGNNIGRFIRFVFTGVM"
BASE COUNT          391 a          421 c          340 g          414 t
ORIGIN      
        1 atctgcgcca ccgtcaggcc gcacgatgcc agccagcggc ggctttcctc actcacccgg
       61 tcagccagga tttcactttc cagccggtcg agcatctgca ccagcaccgg cgggaacacc
      121 acactgccac cgtcttcgcc gccggactgc tgaagcgcat ccgccaggct gcggcgctgc
      181 gttttcgcca gctcaccggt ggcggtttcg accctgatga gtggcgtgaa gctccccggc
      241 tgataaaccg tctggatgcg ggttctgtcg ttctgtatcg tggtcagccg gtcgccgtcc
      301 cagccgtacc aggtcacttc cggtttccgt gacagcgaca tccagcccgt caggtcccgt
      361 tcacgccgcc acacccgttt tgccaccctg cggcccagcg ggtcgtaaag atagcgactt
      421 tcgaccagcg gctctgcgta ttgtgtccgc gtgtagtgca ccagccggtg ccggctgtcg
      481 taatggtacc ggtgagtccg ctcatcatcc gtgcggataa ccccttccgg gatgaggtcg
      541 gttttctctg tcagcctgcc gtgacggtca taccggtaaa ggtagtgcgc gtcacgggcg
      601 atacggttat ccggccacat gctgagggtg ctgtccgggt gcagctccgg gtcgggcagg
      661 cggttacctg ccgggtctgt ggcatacggg atatcaatgc ccaggttaca tataataata
      721 agagcaatta acttaattta tttgtttata atgcgcttac ttaatacaaa ccattgaaca
      781 taccctcctg acagaaaata aagccatatt attatcgcca taatatactt actatcaatc
      841 cttacgccaa taatgtctga aacagtccct ataaatatta gagcaataaa gaatactatg
      901 cctgttggaa aacatattac catcattcca taagacatga gactaattaa ctcgctcaca
      961 tcacgagtgg agtctaatag tgaaagtcta tgcatggaaa agaatagtat taaaagcgat
     1021 aaagccagcc atatagctct gaataaaaaa taatatattt cattacatca ctccggtgaa
     1081 tacaaatcta ataaaacgtc caatgttatt tccggagcac ttcatcttac atgtttctaa
     1141 agaatcatta gaccagtctt ggcagttttt aaatagccct aaatttatag gtgtgaatat
     1201 atcaggcaat acagaataac gcggccttac ctctttaaac ttccctttta aacagttctc
     1261 cacacaacta ttatcggttt caacgaggtc acaacggcca gcagcttctt ttgtatcatt
     1321 acttgcttta cctggccccc atagaccatc tccttttgat tctccccgtt ggtcttggcc
     1381 accacaagta tagtcccctt taccatctgg gacacaaaga tattgatgat agaacggatt
     1441 cccccatata tctggaccgc ttctttcacc agttccgccc attgaatgca gtggcttaat
     1501 gcattttagt gtttctaatc ctaatggatc tatatttgag ttcggattca acggatactg
     1561 ataaaa
//
LOCUS       DADXDL010000258         1527 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.267, whole genome shotgun sequence.
ACCESSION   DADXDL010000258 DADXDL010000000
VERSION     DADXDL010000258.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1527
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.267"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            75..1268
                     /locus_tag="IRB70_004991"
     CDS             75..1268
                     /locus_tag="IRB70_004991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_709453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0634778.1"
                     /translation="MSSKIEDTPQKTLSCWPLAFSAGLLGIGQNGLLVVLPVLVIQTN
                     LSLSVWAALLMLGSMLFLPSSPWWGKQISLTGSKTVVLWALGGYGVSFTLLGLGSVLM
                     ATGAVTTAVGLGILIIARIVYGLTVSAMVPACQVWALQRAGEGNRMAALATISSGLSC
                     GRLFGPLCAAAMLVIHPLAPVWMLMAAPVWAVVMLLRLPGTPPQPTPERKSVSLKRDC
                     LPYLLCAMLLAAAMSMMQLGLSPALTRQFDTDTTTISQQVAWLLGLSAIAALIAQFVV
                     LRPQRLTPVALLLSAGVLMSSGLAIMLTEQLWLFYLGCAVLSFGAALATPAYQLLLND
                     KLADGAGAGWLAASHTLGYGLCALLVPLASKTGVSIALIVTALFAAVLFTIVSACIWH
                     YRTIK"
BASE COUNT          318 a          379 c          434 g          396 t
ORIGIN      
        1 aatgagaaat gttattgtca gaaaaattaa ttttacaaat aaacacaatt aatacatggt
       61 gttgaaacat tacaatgtca tctaagatcg aagatacgcc ccaaaaaacc ctgtcctgct
      121 ggccactggc gttcagtgcc ggtcttctcg gtatcggaca gaacggtctg ctggttgtac
      181 tccctgttct ggtcatacag acaaatctga gtctgtctgt atgggctgcc ctgctgatgc
      241 tgggctcaat gctgtttctg ccatcttccc catggtgggg aaagcaaatt tcccttactg
      301 gcagtaagac tgtggtgctg tgggctctgg gaggatatgg cgtaagcttt accctgcttg
      361 ggctgggaag cgtgctgatg gctaccggtg ccgtaacaac agcggtgggg ttgggaatat
      421 taatcatcgc ccggatcgtc tacggtctga ccgtgtcagc aatggtgcca gcctgtcagg
      481 tctgggcatt gcagagagcg ggagaaggga atcgcatggc cgctctggca accatcagct
      541 ccggcctgag ctgcggcagg ctattcgggc cgctgtgcgc ggcggcaatg ttggtcattc
      601 accctctggc gccagtgtgg atgctgatgg cagctccggt gtgggctgtg gtgatgcttc
      661 tgcggttgcc cggcacacca ccacagccca caccggagcg caagagcgtc agcctgaagc
      721 gggattgcct gccttatctg ctttgcgcaa tgttactggc tgcggcaatg agcatgatgc
      781 agcttggact ttcgccagcc cttactcgcc agttcgatac tgataccacc actattagcc
      841 aacaggtggc gtggttgttg gggctgtccg caatagctgc gcttatcgcg cagttcgtgg
      901 tactccgtcc acagcgcctg actccagtgg ctctgctcct gagtgccggg gtgttgatga
      961 gtagtggtct ggctatcatg ctcactgaac agctatggtt gttttacctg ggctgtgcag
     1021 tgctgtcatt tggggccgct ctggcaacac ccgcttatca acttttactg aatgataagc
     1081 tggccgacgg cgcaggcgcg ggctggcttg cggccagtca cacacttggc tatgggctgt
     1141 gcgcattgtt ggtgccactg gcgtcgaaaa caggtgtctc aatcgcgctg attgtgacgg
     1201 cattatttgc cgctgtatta tttaccatag tgtctgcatg tatttggcat taccgtacaa
     1261 tcaagtaagg ctatgatgtt gtactcacag ctggcataac gtcctgtgca atttcgctgt
     1321 cgaaaccgcc tgtgctgacc gcccagtgca ctcacctgaa gcacatcgca gcatgccacc
     1381 aggatgccag atcgtcttct gaaatgggtg gatacattgg caacgttaac cgcaacaatt
     1441 tttcagagag aattttgggg ggtgagggcc agtgatgtaa aaaatacgcc aagaggttaa
     1501 ttcattgttt atactgatat gtcaggt
//
LOCUS       DADXDL010000259         1504 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.269, whole genome shotgun sequence.
ACCESSION   DADXDL010000259 DADXDL010000000
VERSION     DADXDL010000259.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.269"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            121..407
                     /locus_tag="IRB70_004992"
                     /pseudo
     CDS             121..407
                     /locus_tag="IRB70_004992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000766809.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing N-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2726 domain-containing protein"
     gene            479..613
                     /locus_tag="IRB70_004993"
     CDS             479..613
                     /locus_tag="IRB70_004993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001300273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HBC0634779.1"
                     /translation="MTKYTLIGLLAVCATVLCFSLIFREQLCELNIHRGNTVVQVTLA
                     "
     gene            910..1020
                     /locus_tag="IRB70_004994"
                     /pseudo
     CDS             910..1020
                     /locus_tag="IRB70_004994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052674.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
     gene            complement(1089..>1504)
                     /gene="istB"
                     /locus_tag="IRB70_004995"
     CDS             complement(1089..>1504)
                     /gene="istB"
                     /locus_tag="IRB70_004995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016243248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS21-like element IS100kyp family helper ATPase
                     IstB"
                     /protein_id="HBC0634780.1"
                     /translation="GYEAVRAGIKVRFTTAADLLLQLSTAQRQGRYKTTLQRGVMAPR
                     LLIIDEIGYLPFSQEEAKLFFQVIAKRYEKSAMILTSNLPFGQWDQTFAGDAALTSAM
                     LDRILHHSHVVQIKGESYRLRQKRKAGVIAEANPE"
BASE COUNT          384 a          344 c          377 g          399 t
ORIGIN      
        1 tcagccagag gaaattccca ttctggacca gcgggagcat acgaacaata attttcggct
       61 tcgcgctata gcgggctcaa gttaggttgt cccctgaatc tccagacaac taatatctga
      121 tcgcgccagt ggtggctgtt attcaggatg gtatctcagt gcatgtcgat gtggttatcg
      181 ttgaacggcg ttcgttcagt attgttgcag cagtatagct ggctgatgac agtcatttac
      241 gttcggaacg cagatgctgg gatactcttc tggaagaggt tctgaggcag gctggcattc
      301 cgttgctcag aagtcacgat gcaagaaaac tgctgcagat gaccgaagaa tggctgaata
      361 agacgcaggt ttcagaaatg cgaagacccc actcgttaat ccattaactc gtgaggtctg
      421 catgatgcac tttagcacta ctgattgtag cctcttcttt gcaaagatgt caaagtttat
      481 gacgaaatat acccttatcg ggttgcttgc cgtgtgcgcc acggtgttgt gtttttcact
      541 gatattcagg gaacagttat gtgaactgaa tattcacagg ggaaatacag tggtgcaggt
      601 aactctggcc tgaagcacgg aagtaagctg ccgggcgggg acggaagtcc ccgctttccg
      661 gaagtgtgag gtatttcagg ggcagacacc cgaaatgcta gaaactgccg gtcccgcccg
      721 gggccggtac cctggttaaa gcatttccta cttttcagtc attttattat caaaattaca
      781 ttaaacggtc gtaatcagac atgatttgtg cgccaacaca gatcatcgtc acaactttca
      841 agtcgctgat ttcaaaaaac tgtagtattc tctgcgaaac gatccctgtt taagtattga
      901 ggaggcgaga tgtcgcagac agaaaataca gtgacttcct catctggcgc aaaacgagca
      961 tacagaaagg ggaatccgct ttctgatgca gagaaacaaa gattatcagt ggcccgtaaa
     1021 agtgtcaacg acggatgaaa agtgatccac ttatatctcc accaacggcc caatattgat
     1081 ccaccgtttt actcaggatt agcttctgct ataaccccgg cctttcgttt ctgtctgagt
     1141 cgatagcttt ctcctttgat ttgaacgaca tgtgagtggt gtaagatacg gtccagcatc
     1201 gctgaggtca gtgctgcatc accggcgaac gtttgatccc actgcccgaa cggcagattg
     1261 gatgtcagga tcattgcgct cttttcgtaa cgtttagcga tgacctggaa gaacagcttt
     1321 gcttcttcct gactgaacgg cagatagcct atttcatcaa tgatgagcag gcggggggcc
     1381 attactccac gctgaagcgt cgttttataa cggccctgac gttgtgccgt agataactga
     1441 agtaacagat ctgctgctgt tgtgaagcga actttgatac ctgcacggac tgcttcatag
     1501 ccca
//
LOCUS       DADXDL010000260         1491 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.270, whole genome shotgun sequence.
ACCESSION   DADXDL010000260 DADXDL010000000
VERSION     DADXDL010000260.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1491)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1491)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1491
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.270"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            22..462
                     /locus_tag="IRB70_004996"
     CDS             22..462
                     /locus_tag="IRB70_004996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020218801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EscU/YscU/HrcU family type III secretion system
                     export apparatus switch protein"
                     /protein_id="HBC0634781.1"
                     /translation="MKSKRRERHQEILSEQLKSDVSNSRLMIANPTHIAIGIYFKPHL
                     SPIPLISVRETNEVALAVRKYAKEIGIPIITDKKLARKIYATHRRYDYVSFENIDEIL
                     RLLLWLEDVENAGQPVPDELLPSEDKFKEGEDTKSENKDNNLKN"
     gene            complement(523..816)
                     /locus_tag="IRB70_004997"
     CDS             complement(523..816)
                     /locus_tag="IRB70_004997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000060689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="invasion protein"
                     /protein_id="HBC0634782.1"
                     /translation="MSLVRYNSKIIITVALISLLSACTRENSLKDTQNKRSGESQAIV
                     DARQFFSEHPEYISSAQLEQKLYREFAQVTTVPAYKEMSMYQLLVISQDRLTH"
     gene            complement(818..1318)
                     /locus_tag="IRB70_004998"
     CDS             complement(818..1318)
                     /locus_tag="IRB70_004998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBC0634783.1"
                     /translation="MQVFSSDVYFTVGTNALLASQKEYYSDLVALVDLGHSFVVIDEH
                     QHRNLKPNTEPVNTLLSNNFIRINKNITLSDLTHFLVSNLHTQNVYSTQEPLTHDEID
                     ILRLCVSYSLKQIAIIKGIDYKTVSYHKIRALNKLNIKGTVELFIALCEWDKHYFKLQ
                     SCIRES"
BASE COUNT          503 a          249 c          271 g          468 t
ORIGIN      
        1 gaacaagaag gaaatccaga aattaagtct aaacgcagag agcgccatca agaaattctg
       61 tcagagcaat tgaaatctga tgtcagtaat agccgtctga tgattgccaa ccctacgcac
      121 attgccatag ggatatactt taagccacat ctgtcaccta tcccattgat ttctgtaaga
      181 gaaactaatg aggtagcatt agccgtaagg aaatatgcaa aggaaatcgg aataccaatt
      241 attacagata aaaaattagc acgaaaaatt tatgctaccc atcgtcgcta cgattatgtt
      301 agcttcgaaa atatagatga gatcttgcgt cttctgctgt ggcttgaaga tgtggagaat
      361 gctggacaac ctgttccaga tgaactgctc ccctcagaag ataaattcaa agaaggtgaa
      421 gacacaaaaa gcgagaataa agacaataat ttaaaaaatt aaacatctat catagtcaga
      481 aatttataag aatctacacg caaaaagcgt gtagattctt atttaatgag ttaaacgatc
      541 ttgcgaaatg acaagcaatt gatacatact catctcttta taagctggaa cagtagtaac
      601 ctgtgcaaat tcgcgatata gcttctgctc tagttgtgct gatgatatat attccgggtg
      661 ttcgctaaag aactgtcttg catctactat cgcttgagat tcgccacttc ttttattctg
      721 agtatccttt aatgaatttt ctctggtgca tgcagagagc aacgatatca gcgcgacagt
      781 tattatgatt ttactattat atcttactaa tgacatatca actttctctt atgcaagatt
      841 ggagtttaaa ataatgttta tcccattcac agagtgctat aaacaactca acagtacctt
      901 ttatgttaag tttatttagg gctcttattt tgtgatatga tactgtttta taatcaattc
      961 ctttgataat ggctatttgt tttaacgaat aagaaacaca taaccgcagg atatctatct
     1021 catcatgggt aagtggttct tgagtggaat acacattttg tgtatgaaga ttcgaaacca
     1081 ggaaatgcgt taaatcagat aatgtaatat tcttattgat cctgatgaaa ttgttgctca
     1141 aaagggtgtt tacaggttct gtatttggtt tgagatttcg atgttggtgc tcatcaataa
     1201 caacgaacga atgtccaaga tcaaccaacg caaccaaatc gctgtaatat tccttttggg
     1261 atgctaataa tgcattagtg cctacagtga agtagacatc actggaaaag acttgcatat
     1321 gccaacctgc actctaaaat catttagggt aaatattacg tgtaaaattt aaaataatgg
     1381 taattgttat atttgcatat caatgaggga atagggtgta taccttaaat tgcaaataaa
     1441 gttatgtatg tagccattta aaatggctct cgaaaattat aatcttttta t
//
LOCUS       DADXDL010000261         1463 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.271, whole genome shotgun sequence.
ACCESSION   DADXDL010000261 DADXDL010000000
VERSION     DADXDL010000261.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1463
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.271"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..671
                     /gene="espX1"
                     /locus_tag="IRB70_004999"
     CDS             <1..671
                     /gene="espX1"
                     /locus_tag="IRB70_004999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type III secretion system effector EspX1"
                     /protein_id="HBC0634784.1"
                     /translation="STENTITNKFDVVFSYCGNNVKEFILLLPYNKSLEMHELNEQNI
                     QYLTALNINIHKMLLSNITIEKSDLSYGYYFGCVLSNILCFESDLSNTIFSNGEINNL
                     FIKKSNIFGTSFTNTMIKNLRCEDIMPGRWTTQLVNKHLGYRYTGVFKTLASIDDKPS
                     RFEILIPLVQTLVRDNVKLNNDVYKELNKFMHDYDKTSSKMRKYLQSINECMLLIKNI
                     VHQD"
     gene            905..1463
                     /locus_tag="IRB70_005000"
                     /pseudo
     CDS             905..1463
                     /locus_tag="IRB70_005000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308049.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="fimbria/pilus outer membrane usher protein"
BASE COUNT          528 a          264 c          236 g          435 t
ORIGIN      
        1 gctcaactga aaacacaatc accaataaat ttgatgttgt cttttcttac tgcggaaata
       61 atgtaaagga atttatactt ttattaccct ataataaatc tctggagatg catgaactta
      121 acgagcaaaa catccagtat ttgactgccc ttaatattaa tatacataaa atgttgctat
      181 caaatataac aatagaaaag agcgaccttt catatgggta ttattttggt tgtgtattat
      241 ccaatatatt atgttttgaa agcgacttat caaacaccat cttttcaaat ggagaaataa
      301 acaacctctt cattaaaaaa agcaacatat ttggaacatc gttcactaat accatgataa
      361 aaaatttgcg ctgtgaagat attatgcctg gccgatggac cactcaactt gtcaataagc
      421 acttaggtta cagatacaca ggagtattca aaaccctggc aagtattgat gacaaaccgt
      481 cccgtttcga aattttgata ccattggtac aaactttagt tcgcgacaat gtaaagctaa
      541 ataatgatgt gtataaagaa cttaataagt ttatgcacga ttacgacaaa acatcatcaa
      601 aaatgagaaa ataccttcag agcatcaacg agtgcatgct ccttataaaa aatatagttc
      661 atcaggatta aaacactcaa agaaagaggt aattttagaa tgaaattatc tgtgatgatt
      721 attaatacac tgcagagaaa taaaaaacaa tctgaagcat gctctgaaac atcctactct
      781 gtcactctaa tgatggcacc ttgctcttct tataaagaag ggaacaatta agaatattaa
      841 attttcaaac tttcatcaac ttcacatcaa gaaattaaaa aatttaaaca ttaatctaaa
      901 taataacaac ctgatcacat aatcgggtac gattttatcc gataactata atgctataac
      961 tctgggaaat ggttggaata caccgctggg tgccatctct ttttacgctg cccgatcgag
     1021 tagtaagtta aataatgata ccagacacga aggtacgagc tatcaggtcg cctataataa
     1081 atatctagta caaacagcca ctcgatttag cgtggccgcc tggcgttatg cttcgcagga
     1141 ttacaggaca ttcagcgacc atctttacga aaatgataaa cactatcatc agagtgatta
     1201 tgatgatttt tatgatattg gcagaaaaaa tagcctttct gctaatatta tgcaaccttt
     1261 atccaataat ctgggaaatg tatcattaag tgcgctttgg cggaattact gggggcgaag
     1321 tggaaatgct aaagattacc aattcagtta ctccaataac tggcaacaca ttagttatac
     1381 tttctctgcc agccaatctt atgatgaaaa taataaagaa gaggagcgtt ttaatctgtt
     1441 tatctccatt cctttctact ggg
//
LOCUS       DADXDL010000262         1451 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.272, whole genome shotgun sequence.
ACCESSION   DADXDL010000262 DADXDL010000000
VERSION     DADXDL010000262.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1451
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.272"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..588)
                     /locus_tag="IRB70_005001"
     CDS             complement(<1..588)
                     /locus_tag="IRB70_005001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000369293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III effector protein"
                     /protein_id="HBC0634785.1"
                     /translation="MDNLIGTPPNHSVPHKYIDMEQMEYLCHLNRFSKLSDDFLINGP
                     RDDLFTYKYVLDGSFSNLQHLLPKGQLQKIQQRLSSLIDKNKFHCFHIFLLKLCSIEN
                     IPVPNADYAFFDDEMPFTLTDEQIENISFLNAYHKEKKGNNDIVTFDFMSYDHHHNFS
                     TTIALTNDSFHISSINNHNAQVIFDENVLLYTNELP"
     gene            889..>1451
                     /locus_tag="IRB70_005002"
     CDS             889..>1451
                     /locus_tag="IRB70_005002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III effector"
                     /protein_id="HBC0634786.1"
                     /translation="MVAKLKPDVFVNTNPFLEAMYKERLSHKGYSDKIALSINDKKYN
                     VNSKDIENILDGKGDLFKKRTLWEFVRDLFPGSHIKEVKGLIYEFVTKVDNKAEVFDK
                     IKSLAKKEQQWRFSTKTDFTTNENNEVIVSRSFNLYTGATSNDNEKKQVSSERLTLDN
                     YIDDLHFDNSPLKRFTFDDYAVKLTTL"
BASE COUNT          506 a          202 c          257 g          486 t
ORIGIN      
        1 tggtaattca ttggtgtata aaaggacgtt ttcatcgaat ataacctgtg cattatggtt
       61 atttattgaa gatatatgga agctatcatt tgttaaagct atggttgtgc taaaattatg
      121 atggtgatca tagctcatga aatcaaatgt aacaatgtcg ttgttccctt tcttttcttt
      181 gtgatatgcg tttaaaaaag aaatattttc gatctgttca tcagttaatg taaatggcat
      241 ttcgtcatca aagaaagcat aatcggcatt tgggactgga atattttcaa ttgagcatag
      301 ttttaataaa aaaatatgaa aacaatggaa cttatttttg tcaataagag aacttaatct
      361 ctgttgtatc ttctgtagtt gtcctttggg aagtaaatgc tgtaaatttg aaaaagagcc
      421 atctaaaaca tatttgtatg taaaaaggtc atctcttgga ccatttatta aaaaatcgtc
      481 agacaattta gaaaaacgat tgagatgaca taaatattcc atttgctcca tgtctatata
      541 cttatgggga actgagtggt ttggtggtgt gccaataaga ttatccataa atcaccttga
      601 taaaatttaa taaaatctat ttattttaac ctcgacaata aaagcggcta taaaaaaacg
      661 ctcattttct gttgctgcgg ttaacccgtg gaatgtaccg ttaaccccca aaaaattgca
      721 aatccagggt gaacaccctg ggttaaaatg gaaataatga gctatttttt acagtattca
      781 ccggtaatat aagtaacact tgttgctaac ctaactagca gtacagttaa ttaacaacat
      841 agaagttatt gtttttcaaa caactcaata tttcacgccg gaggatttat ggtcgctaaa
      901 ttaaaaccag atgtttttgt taatactaat ccttttttag aagcaatgta taaggagagg
      961 cttagtcata aaggctattc tgataaaatt gctttaagta ttaatgataa gaaatataat
     1021 gtaaactcta aggatattga aaatattctt gatggcaaag gggatttatt taaaaaacgt
     1081 acactgtggg agtttgttcg cgatcttttt cctggatctc atattaaaga agtcaaaggt
     1141 ttaatttacg aatttgtcac gaaagttgat aataaagccg aggtgttcga taagattaaa
     1201 tctctggcaa aaaaagaaca acaatggcga tttagtacta agacagactt taccacaaat
     1261 gaaaataatg aagttattgt gagtagatcc tttaatctct acacgggggc tacttcgaat
     1321 gataacgaaa aaaaacaggt ttcttcagag agattaacgc ttgataatta tattgatgat
     1381 ttacattttg ataattctcc cttgaagaga tttacgtttg atgattatgc tgtaaaactt
     1441 acgacactga t
//
LOCUS       DADXDL010000263         1442 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.273, whole genome shotgun sequence.
ACCESSION   DADXDL010000263 DADXDL010000000
VERSION     DADXDL010000263.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1442)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1442)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1442
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.273"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            59..1192
                     /locus_tag="IRB70_005003"
     CDS             59..1192
                     /locus_tag="IRB70_005003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000555401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBC0634787.1"
                     /translation="MHSENIAAYIGLDVHKETLAVAIAAPERLGEVRYYGTINNEAQA
                     VRRLFQKLQGLYGNILSCYEAGPCGFGLYHQLTAMNIKFQVIAPSRIPKSPTDRIKND
                     HRDAISLARLLRAGELTPVWIPDLTHEAMRDLIRARAAAKRDSRVARQRILSMLLRTD
                     KRYAGKHWTGKHRTWLANQSFSQPSQQIAFQHYCQSLEQIEDRILQLDQEISRLLPEW
                     SLCNLVCQLQALKGVGQLIAITLVAELGDFSRFSNPKQLMAFLGLVPGEYSSGNSIRP
                     RGITKVGNSELRRLLYEAAWSYRTPAKVGAWLIYYRPDSVTQYSKDIAWKAQQRLCSR
                     YRTLTAKGKKSQVAITAVARELTGFMWDIALAAQSSFSQQKQN"
BASE COUNT          411 a          321 c          337 g          373 t
ORIGIN      
        1 tggtatgacc tttatatact cactatagca ttggtgggat attccagagg aggtcattat
       61 gcattcggaa aatattgcag cttacatcgg gctggatgta cataaagaaa cgttggcggt
      121 tgctattgct gcacctgaac ggcttggcga agttcgttat tatggtacga ttaacaacga
      181 agcccaggct gtacgtcgat tatttcagaa attgcaggga ctttacggaa acattctttc
      241 ctgctatgag gctggcccct gtggttttgg gctatatcat caactcacag cgatgaatat
      301 aaaattccag gttattgccc cttcccggat accaaaatca ccgacagaca gaatcaaaaa
      361 tgatcatcgg gacgcaattt ctcttgccag gttactgcgg gctggtgaac ttacccctgt
      421 ctggatccct gacctgactc atgaagctat gcgggatcta atcagagccc gtgcagcagc
      481 taaacgagac agcagagttg cccgacagcg aattctgagc atgctattgc gaacagacaa
      541 acgttatgca gggaagcact ggaccggcaa acatcgaacc tggttagcta atcaatcatt
      601 tagtcagcca tctcagcaga ttgcttttca acactattgt caaagtctgg agcagattga
      661 agatcgcata cttcaactcg accaggaaat atctcgcctg ttacctgagt ggtctctgtg
      721 caatctggtc tgccagttgc aggctctaaa aggtgttggt cagctaattg caataaccct
      781 ggttgctgaa ctgggtgatt tttcgcgatt ttccaatccc aaacagctca tggcttttct
      841 gggactggtg ccaggtgaat attccagtgg aaacagtatt cgtcccagag gaataacaaa
      901 agttggaaac agcgaactga gacgtctgct ttacgaagcc gcctggtctt atcgtacacc
      961 tgcaaaagtt ggtgcatggc ttatatatta ccgaccggac tctgtaacac aatattccaa
     1021 agatattgca tggaaagctc aacaacgatt gtgttctcgt taccgaactc tgacagcaaa
     1081 agggaaaaaa tcacaagtag ccattacggc ggtggctcgt gagttgactg gatttatgtg
     1141 ggatattgca cttgctgccc aatcatcatt cagtcagcag aagcaaaatt aaaccctgaa
     1201 gcagtcagac acggaatgag tgatcctcga aaaagaattc agggaagcca gaatgcgcta
     1261 atacctgcac gtagaaagag gccagctcac tgcgtaaatc gtcatggggc taaaatcccc
     1321 gaataagagt ttgtaaaatc caagatacag tctgactgtt tcaggttctt taatccgcga
     1381 tataacgaag ctcccggagc tgcgtaggtc tttttgggct taatatttga caaaggtcat
     1441 aa
//
LOCUS       DADXDL010000264         1360 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.274, whole genome shotgun sequence.
ACCESSION   DADXDL010000264 DADXDL010000000
VERSION     DADXDL010000264.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1360
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.274"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..968
                     /locus_tag="IRB70_005004"
     CDS             <1..968
                     /locus_tag="IRB70_005004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708766.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634788.1"
                     /translation="RLIRRGHLTYTQARNITRFGTIESVTYDIAEGSVVSLAAGGISF
                     ALTASVFWLSTGDRDAALQTAAVQAGKTFTRTLAVYVTTQQLHRLSVVQGMLKHIDFS
                     TASPTVRLALQKGTGAGNISALNKVMKGTLVTSLALVAVTTGPDMIKMLRGRISGAQF
                     IRNLAVASSGVAGGAVGSVAGGILFSPLGPFGALTGRVVGGVLGGMIASAVSGKIAGV
                     LVEEDRVKILAMIQEQVTWLAGSFLLTGHEIENLNENLARVIDQNALEIIFAAGIQQR
                     AATNMLIKPLVVSIIRQRPVMEYDASHLGNMVNRLEEALPPELPA"
     gene            1044..>1360
                     /locus_tag="IRB70_005005"
     CDS             1044..>1360
                     /locus_tag="IRB70_005005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634789.1"
                     /translation="MIHLFKTCMITAFILGLTWSAPLRAQDQRYISIRNTDTIWLPGN
                     ICAYQFRLDNGGNDEGFGPLTITLQLKDKYGQTLVTRKMETEAFGDSNATRTTDAFLE
                     TECV"
BASE COUNT          319 a          346 c          373 g          322 t
ORIGIN      
        1 cccggctgat tcgtcgggga catctgactt atactcaggc ccgtaatatc acccggttcg
       61 ggaccatcga atcggtcact tatgatattg ccgagggttc ggttgtcagt ctggcggccg
      121 gagggatcag ttttgccctg acggcatcgg tcttctggct cagcaccggc gatcgcgatg
      181 ctgccctgca gacagctgct gtccaggcag gaaaaacctt cacccgcaca ctggctgtct
      241 acgtcacaac ccagcaactc caccggctca gtgttgttca gggtatgctg aagcacattg
      301 atttttcgac tgccagcccg actgtccgac tggctcttca gaaggggacc ggtgcaggaa
      361 atatcagtgc cctgaacaaa gtaatgaagg gtacgctggt gacatctctg gcactggtag
      421 ctgtcacaac cggccctgac atgatcaaaa tgttgcgggg acggatctcc ggtgcgcagt
      481 tcatcaggaa tcttgccgtg gcatcttccg gtgtggcagg tggtgctgtc gggtcagtgg
      541 cgggcgggat actgttcagt ccactgggac catttggtgc actgacaggg cgtgtggttg
      601 gcggtgttct ggggggaatg attgcctccg ctgtatcagg aaaaattgcc ggagtgctgg
      661 ttgaagaaga tcgcgtcaaa attctggcaa tgattcagga gcaggtgaca tggcttgccg
      721 gcagtttcct gctgaccgga catgagattg aaaatctgaa cgagaatctg gcccgtgtta
      781 tcgatcagaa tgctctggag atcattttcg ccgccggtat acaacaacgg gccgcgacca
      841 atatgttaat caaaccactg gtggtcagta tcatcaggca acgccccgtc atggaatatg
      901 atgcatccca tctcggcaat atggttaacc gactggaaga agcattaccc ccggagttac
      961 cggcataacg gctattctgc gccttttacg ctttatcacc tgatttgtca gtgtcatcgt
     1021 catgactcag agaggtaaat accatgattc acctgttcaa aacctgcatg attaccgcct
     1081 tcattctggg gttaacgtgg tctgccccac tccgggcaca ggatcaacgt tacatcagta
     1141 tacgcaatac agatacgata tggctcccgg gaaatatttg tgcttaccag ttccggctgg
     1201 ataatggcgg aaacgatgaa ggatttggcc ccctcaccat cactctgcaa ctcaaagaca
     1261 aatatggtca gacgctggtg accagaaaaa tggaaacgga agcttttggt gacagtaatg
     1321 ccacgcgaac cacagacgca tttctggaaa cggagtgcgt
//
LOCUS       DADXDL010000265         1356 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.275, whole genome shotgun sequence.
ACCESSION   DADXDL010000265 DADXDL010000000
VERSION     DADXDL010000265.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1356)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1356)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1356
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.275"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            24..380
                     /locus_tag="IRB70_005006"
     CDS             24..380
                     /locus_tag="IRB70_005006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001459679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RusA family crossover junction
                     endodeoxyribonuclease"
                     /protein_id="HBC0634790.1"
                     /translation="MLIDLVLPYPPTVNTYWRRRGSTYFISEEGKRYRRAVALIVRQQ
                     RLKLSLSGRLAIKVIAEPPDKRRRDLDNILKAPLDALTHAGVLMDDEQFDEINIVRGQ
                     PVSGGRLGVKIYPIMH"
     gene            395..1216
                     /locus_tag="IRB70_005007"
     CDS             395..1216
                     /locus_tag="IRB70_005007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_707426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitermination protein"
                     /protein_id="HBC0634791.1"
                     /translation="MKLEDLPKYYSPKSPGLTDASASTSKDALSITDVMAAQGMTQNR
                     AEMGFSAFLGKMGISMNDRARATELLADYALSRCDRVAALRKLPAEIKPVVMRIMASY
                     AFEDYARSAASKKQCPCCYGEKFIESIVFTNKVQYPDGKPPVWAKCTKGVYPSYWEEW
                     KKVREVVKVACPECGGKGEVSTACKDCRGRGVAIHREESVKRGMPVVRDCQRCGGRGY
                     ERLPSTEAFNAICEVTNQITRASWEKTVKKFYDALVTRFDIEEAWAERQLKKVTR"
BASE COUNT          355 a          269 c          401 g          331 t
ORIGIN      
        1 tgcttgggta aaagaggtga ctgatgctca tagatttggt tttaccttac ccgccgacgg
       61 tgaacactta ctggcgacgc cgtggcagca catattttat ctcggaggag ggaaagcgtt
      121 atcgccgggc tgtggcgctt attgttcgcc agcagcggct gaaattaagc ctgtccggaa
      181 ggctggcgat aaaggtgatt gcagagccac cggataagcg tcgtcgcgac ctggacaata
      241 tcctgaaagc accgctggat gcgctgacgc atgcgggagt gttaatggac gatgagcagt
      301 ttgatgaaat caatatcgtt cgtggtcagc cagtatctgg cggacgtctg ggggtgaaga
      361 tttaccccat aatgcattaa gagcaggtca aaaaatgaaa ctggaagatt taccgaaata
      421 ctactcccca aaatcccctg gcctgaccga tgcatcggcc tcaacgtcaa aagatgcgct
      481 gagtatcact gatgtgatgg ccgcgcaggg catgacacag aatcgggctg agatgggttt
      541 ttctgcgttc ctggggaaaa tgggcatcag tatgaatgac agggcgcggg caacagaatt
      601 actggcagat tatgcactca gtcggtgcga tcgtgtggcg gcgttgagaa aacttccggc
      661 agaaataaaa ccggtagtga tgcgcattat ggcttcgtac gcttttgagg attatgcccg
      721 cagcgcagcg agtaaaaagc agtgcccttg ttgctatggg gaaaaattta ttgaaagcat
      781 agtttttaca aacaaggtcc agtatccgga tggtaagccg ccggtatggg caaagtgtac
      841 gaaaggtgtg tatccgtctt actgggaaga atggaaaaaa gtcagggagg tggtaaaagt
      901 tgcctgtccg gagtgtggcg gaaagggtga ggtttccacc gcctgtaagg attgccgtgg
      961 gcgtggtgtc gccattcatc gtgaagagtc ggtaaaacgt ggtatgcctg ttgtcagaga
     1021 ctgccagcgt tgtggtggtc gtggctatga aagactacca tcaacggagg catttaatgc
     1081 tatatgcgag gtgacaaacc agataacacg cgcgtcatgg gaaaaaacag ttaagaaatt
     1141 ctatgatgcg ctggtgaccc ggtttgatat tgaagaagca tgggctgagc ggcagttaaa
     1201 aaaggtaact aggtaacaag gttgattttt ccggaatctg tggtaaattc gtcataatga
     1261 tgggcttttt atgcctgacg ttagaagagt ttctacaacc cgccgccgag cgggtttttt
     1321 attgcggaat taattacgga ccgttattat tctgct
//
LOCUS       DADXDL010000266         1313 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.276, whole genome shotgun sequence.
ACCESSION   DADXDL010000266 DADXDL010000000
VERSION     DADXDL010000266.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1313)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1313)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1313
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.276"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>1313)
                     /locus_tag="IRB70_005008"
     CDS             complement(<1..>1313)
                     /locus_tag="IRB70_005008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HBC0634792.1"
                     /translation="KCIIKCKDAYDISRYHESISKKFKTVSIHETFRNDEASGKFKSV
                     NSALKSDNIRVLIHQHKLDEGVDLPEAKLLVLTYQVGSGRELVQTIGRVVRNYNSIEP
                     MIIDLASSSNERMWQSYRVFDDYISTPSGSKGFIKSLSTTNLIKGFLDNFPEYSYFSS
                     RFRERLDLQSINANDISIPLASVCFIEKGPNYSTPLLLDKIYWELHTQGSLVKEIKND
                     HNVFMYLYISFNSSRYLSDKLFFEPKLEIIIIKELSNSIAIFDSAGAKYANRIDLNLA
                     NPININRLTALAAATKVREIKEAHSRAIGTAKNRPEAMSLKGKNLENINSTQRNAMYA
                     LTTLKVVNKDEQGKNDSSFYIGARSGRVSDQMERNFSIEELSEWIEKIDLGTAKEATN
                     NGRLIKSFSQPINEKPNSDIVSIILDLSDFDTELISEKNFLPDYY"
BASE COUNT          371 a          218 c          219 g          505 t
ORIGIN      
        1 ataatagtcc ggtaggaaat tcttttcgga aattaattcg gtatcgaaat ctgataaatc
       61 tagaataatt gaaactatat cggaattggg tttttcattg atgggttgtg agaatgactt
      121 tattaatcgg ccattattag ttgcttcttt tgctgttcct aaatcaattt tttcaatcca
      181 ttcagatagt tcttctatac taaaattcct ttccatttgg tcagagacac gaccagacct
      241 agcccctata tagaaactac tgtcattttt cccttgttca tccttattaa ctactttcaa
      301 tgttgttagt gcgtacatgg cattgcgctg agtgctattt atattttcta ggtttttacc
      361 ttttaaggac atcgcttccg gtctattttt tgcagtacct atagcccttg agtgagcttc
      421 ttttatttca cggacttttg tggctgcagc taatgctgtt aatctattaa tatttatagg
      481 gtttgcaaga tttaagtcga ttctatttgc atacttggca ccagcgctgt caaagatagc
      541 tatgctatta gataactctt taattattat tatttctagc tttggttcaa aaaataattt
      601 atcagaaaga tacctggagc tattgaatga tatgtataga tacatgaata cattatggtc
      661 attttttatt tctttaacaa gtgaaccttg tgtatgcagt tcccaatata ttttatccaa
      721 aagaagggga gttgagtaat taggcccttt ttctataaag caaacggatg ccaatggtat
      781 tgaaatatca ttggcattta tggattgcaa gtccaatcgt tctctgaaac gactagagaa
      841 gtagctgtat tcagggaagt tatcaagaaa tccttttatt aggttagttg tgcttagcga
      901 ttttataaat ccttttgaac cgctaggtgt ggatatgtag tcatcaaata cgcggtaact
      961 ttgccacatt ctttcattgg atgaactagc tagatctatt atcatcggtt ctattgaatt
     1021 gtaattccta acaactctcc caatagtttg aaccaattct ctaccacttc caacttgata
     1081 ggttaaaact agtaattttg cttcaggcaa atctacacct tcatcaagtt tatgttgatg
     1141 aattagaact cttatgttgt cagattttaa tgcggaattt actgatttaa atttaccgct
     1201 agcttcatca tttctaaatg tctcatgtat acttactgtt ttgaattttt tagaaattga
     1261 ttcgtggtat cgagatatat cataggcatc tttacatttt attatgcatt tta
//
LOCUS       DADXDL010000267         1308 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.277, whole genome shotgun sequence.
ACCESSION   DADXDL010000267 DADXDL010000000
VERSION     DADXDL010000267.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1308
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.277"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..802
                     /locus_tag="IRB70_005009"
     CDS             <1..802
                     /locus_tag="IRB70_005009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001090972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="amidohydrolase family protein"
                     /protein_id="HBC0634793.1"
                     /translation="PEDYFADVGDINIVETCYMETEWNPTDPCGESDFITSVAKMTGY
                     PNAVVGQAWLNHDDIDSVLKMQSSYKLMRSIRHKPEGPDKPEDVGQYTTLMSDEKWRY
                     GYSLLSKYNLMFDLQTQWWNLHEAVKLANDFPDTVIILNHTGLPAQRSAEGLAGWHSA
                     MASLAECQNVMVKISGIGLKGIPWTMENNLWIISETLSMFGPDRVMFASNFPVDSLCG
                     SFTNIFHGFMTVCEMKGYSHAAQRKMFHDNCKRIYRTIPPHKLKEKHS"
BASE COUNT          429 a          250 c          252 g          377 t
ORIGIN      
        1 tccagaagat tattttgcag atgtaggtga tattaatatt gttgaaacat gttatatgga
       61 aactgaatgg aatccaacgg atccatgtgg tgaaagcgat ttcattacat cagtggcaaa
      121 aatgacaggt tatccaaatg ctgttgtcgg tcaggcttgg ttaaaccatg atgatataga
      181 ttctgtatta aaaatgcaga gctcatataa gctaatgcga agcatcagac ataaacctga
      241 aggcccggat aaaccagaag atgttggaca gtataccaca ctgatgagtg atgaaaaatg
      301 gcgatatggc tattcgttac tttcgaaata taatttaatg tttgaccttc agacccagtg
      361 gtggaacctg catgaagcag taaaacttgc aaatgatttt ccagatacag tcataatact
      421 taaccataca ggacttcctg cacaacgatc tgctgaaggg cttgccggtt ggcattcagc
      481 aatggcttct ttagctgagt gtcaaaatgt tatggtcaaa atttcgggaa taggtttaaa
      541 aggaatccca tggacaatgg agaataattt atggattata tctgaaacct tatcaatgtt
      601 tggtcctgac agggtaatgt ttgcaagcaa tttccccgta gatagccttt gtggcagctt
      661 tactaatata ttccatggtt ttatgacagt gtgtgaaatg aaaggatatt cgcatgccgc
      721 tcagcggaag atgtttcatg acaattgtaa gagaatttat cgaacaatcc caccacataa
      781 attgaaagaa aagcatagct aataaccata caacaaaacc tgatatttat tgtgatatat
      841 aacgtatcaa actttataac ttttaaatat atgttatgtt catactatgt cgaatgatag
      901 tgctcaagta gcacatctaa aaagacaatg caaaacagta ataacccccc ttgctaaaaa
      961 aaggggggta tcatccctac accgtctcca aaggagatgg agatagttcc tataaggtca
     1021 tagcctaaaa aatacccatg acggaatatc tcaacttact caccacaatt aaaaagagac
     1081 aaaatgacat ggagtttatg tgacctcatc ccattttgca cagcctccat tgttctgaca
     1141 ttgacggcag gttgccgctt tatatccggc tttattgcag ccataaagtt atgtgccact
     1201 atataattct ctgactcaca cttcatttac tgcacgggct tcaagcccaa acctcatgca
     1261 ggtttagtga gtcccaatct tacctgtctt tatcatctgt cacgaacg
//
LOCUS       DADXDL010000268         1299 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.278, whole genome shotgun sequence.
ACCESSION   DADXDL010000268 DADXDL010000000
VERSION     DADXDL010000268.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1299
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.278"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..546)
                     /locus_tag="IRB70_005010"
     CDS             complement(<1..546)
                     /locus_tag="IRB70_005010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001368704.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBC0634794.1"
                     /translation="MGNAMHSLKTLLQLPCGWRCSRQIISSDGITLHLHGKRKTAQCP
                     ECFKRSDSVHSCRRRRIQHLPCSGQTLWLVFSVRHWYCRNPACSRKIFAESLAPFAGS
                     HQQSSQALQNLQRQLGLIAGGEAGKRAATAAGLRCSADTLLRRVINTPETKQSGAPHV
                     GIDEWAWHRGHCCGMLIVNLDT"
     gene            complement(830..1239)
                     /locus_tag="IRB70_005011"
                     /pseudo
     CDS             complement(830..1239)
                     /locus_tag="IRB70_005011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016238421.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
BASE COUNT          320 a          362 c          297 g          320 t
ORIGIN      
        1 agtatcaaga ttgactatta acataccgca gcagtggccc cgatgccacg cccactcatc
       61 aataccgaca tgaggcgcgc ctgactgttt cgtctccggg gtattgataa ccctgcgaag
      121 aagagtatca gcactgcaac ggagacccgc tgccgttgca gcccgttttc cagcctcacc
      181 tccagctatt aatcccagtt gacgttgtaa attttgtaac gcctgtgaag actgctggtg
      241 tgaaccggcg aagggagcaa gcgactcggc aaaaatttta cgtgaacaag ccgggttacg
      301 gcagtaccag tggcggacgg aaaatacaag ccatagcgtc tgccctgagc agggtagatg
      361 ctgtatccgg cgccgacgac aactatgaac agagtcgcta cgcttaaagc attcaggaca
      421 ttgtgctgtt ttgcgttttc cgtggagatg gagggttata ccgtcagagc taataatttg
      481 tcgactgcat cgccatccgc aaggtaactg tagaagtgtc ttaagagagt gcattgcgtt
      541 gcccataact taaaacagct tagatccttg ttcgccagaa agtttcatcc attttcttcc
      601 acccaggtag cggaagaacc acttttcatc cgtcgttgac agatgtgaag tatgcgggag
      661 aaaaagtgaa tatctaactg taataactca gaccggtacg agtactcgga acgtctacaa
      721 tcattcaggg caaagtgcta aaatttctct atcccgggat gcccctacca acgcagcact
      781 cccggagata tcattacagc tctgcaactg atttccgcga ctgaaccgct cagttcctat
      841 ccttccagtt gccttcctgc agcccccctc cctgctgtat accccggtac cacaacgcgg
      901 gcagcacttt tctccttcat aatcttcgtc acacatcaca caaaaccact ttctcacctt
      961 caccgtataa tccggaaccg tcataccctg cagatgcaaa cgacgggcct ctttctctgc
     1021 cgggtcaagc caggtgcatc gcagcaggat tttctcagcg acagtcatct ggtcatgttc
     1081 aaaccacggt ggttgtccgt cattgccccg ctgaagtgtt aacgggcatc cacaggacac
     1141 acagcacaaa acgtcctggc ggttgtgctt cgctgcttct ttcgccgtaa caaaatggcc
     1201 tttgctgtca ttcgccatat aacagttcag aattcgcata tttcctcctg agttgtccgg
     1261 ggaatactga atcctccggt ctggcagtgt gtgcagtac
//
LOCUS       DADXDL010000269         1290 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.279, whole genome shotgun sequence.
ACCESSION   DADXDL010000269 DADXDL010000000
VERSION     DADXDL010000269.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.279"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..531
                     /locus_tag="IRB70_005012"
     CDS             <1..531
                     /locus_tag="IRB70_005012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000608445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IpaD/SipD/SspD family type III secretion system
                     needle tip protein"
                     /protein_id="HBC0634795.1"
                     /translation="MHFYYIDKYPNGDFHYHYNPDYVLYPPAPADKIGVPLEEAEKWC
                     AALGLPVIPPDPKHRTPSPIVEVEPQGSGLYVIIPNPQIIDSMSQSSDSMVHRDDKGK
                     EKNISKEFTGYEISTAEYQAWLAGYNGQAENMKTDVQVITTKYSTANSTYDTIIKLLS
                     STITALFDSAKDYLRF"
     gene            734..>1290
                     /gene="eilA"
                     /locus_tag="IRB70_005013"
     CDS             734..>1290
                     /gene="eilA"
                     /locus_tag="IRB70_005013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001176839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HilA family transcriptional regulator EilA"
                     /protein_id="HBC0634796.1"
                     /translation="MQLQHGKNNTQQYIFGDFVLKNNGILLFKNKEYHIPPKELGVII
                     LLLNADGEIVSKEEIIDKVWSASVASDESLTRCIYALRKLLHENKQCKYIETVYGRGY
                     RFTVPIVIVTDNEPVKSTTTLAVFPFRTEGSINVLKLHYELVQGLSKYAFCGLDILPA
                     SVTNEASDFSTIHQFINKTGPEYYI"
BASE COUNT          417 a          260 c          230 g          383 t
ORIGIN      
        1 atgcattttt attatatcga taaatatcct aatggtgatt tccactatca ttacaatcca
       61 gactatgttt tataccctcc ggcacctgct gacaaaattg gtgtaccact agaagaagca
      121 gaaaaatggt gcgccgcttt aggacttccg gtaattccac ccgatcccaa acaccgcaca
      181 ccttctccga ttgtcgaagt tgaaccgcaa ggtagcggtc tgtatgttat tattcccaac
      241 cctcagatta ttgacagtat gagtcagtct tcagactcaa tggtgcatag ggacgataaa
      301 gggaaggaaa aaaatatatc taaagaattc accggttatg aaataagcac agctgaatac
      361 caggcatggc tggcgggtta taacggccag gcagaaaaca tgaaaaccga cgtgcaggtt
      421 atcacgacta aatacagtac agccaactcc acctacgata caattatcaa attattatct
      481 tcaaccatta ctgcgttgtt tgattcagcg aaagattatt tacgtttctg attaagtaac
      541 acccacaatt atcgcctact atctggtccc gaaaaatggg accagcgttt catattatta
      601 agcatcagct ttcattcatt tcttcatcac aatcttacaa aatgagcgtt ttttgataga
      661 gcaattctgc caatacttta ttttatatta atcaaattaa tactatgaat agagaaaacg
      721 gaaggagcgt tctatgcaac tgcaacatgg aaaaaataat acacaacaat atatatttgg
      781 cgactttgta ttaaaaaaca atggaatatt attattcaaa aacaaagaat atcatattcc
      841 cccgaaagaa cttggcgtta tcattctatt acttaatgct gacggtgaaa ttgttagcaa
      901 agaagagatt atcgataagg tctggagcgc gagtgttgcc agtgatgaat ctctaacacg
      961 atgtatttat gcattgcgca aacttttgca tgagaataaa cagtgtaagt atatcgaaac
     1021 ggtctatggt cgtggatacc gttttactgt acctattgtg attgtgaccg ataatgaacc
     1081 ggtaaagtcg accaccactc ttgccgtttt tccctttcgt actgaaggtt cgatcaatgt
     1141 tctaaaactc cattacgaac ttgtccaggg cctttcaaaa tatgcttttt gtggtttaga
     1201 tattttaccc gcttcggtaa caaatgaggc cagtgatttc tccaccatcc atcagtttat
     1261 caataaaaca ggtccagaat attatattat
//
LOCUS       DADXDL010000270         1290 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.280, whole genome shotgun sequence.
ACCESSION   DADXDL010000270 DADXDL010000000
VERSION     DADXDL010000270.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.280"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1227
                     /gene="ag43"
                     /locus_tag="IRB70_005014"
     CDS             <1..1227
                     /gene="ag43"
                     /locus_tag="IRB70_005014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HBC0634797.1"
                     /translation="GRATGKTILNLVNAGNSASGLATSGKGIQVVEAINGATTEEGAF
                     IQGNRLQAGAFNYSLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRILAGSRSH
                     QTGVSGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLLRTEVAGMS
                     VTAGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLIHNASGLWADIVAQGTRH
                     SMKASSDNNDFRVRGWGWLGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGQDNAGY
                     VKFGHGSAQHVRAGFRLGSHHDMNFGKGTSSRDTLRGSAKHSVRELPVNWWVQPSVIR
                     TFSSRGDMRVGTSTAGSGMTFSPSQNGTSLDLQAGLEARVRENITLGVQAGYVHSVSG
                     SSAEGYNGQATLNVTF"
BASE COUNT          270 a          365 c          403 g          252 t
ORIGIN      
        1 ggcagggcaa ccggaaaaac catcctgaac ctggtgaacg ccggcaacag tgcgtcgggg
       61 ctggcgacca gcggtaaggg tattcaggtg gtggaagcca ttaacggtgc caccacggag
      121 gaaggggcct ttatccaggg gaacaggctg caggccggtg cctttaacta ctccctcaac
      181 cgggacagtg atgagagctg gtatctgcgc agtgaaaatg cttatcgtgc agaagtcccc
      241 ctgtatgcct ccatgctgac acaggcaatg gactatgacc ggattctggc aggctcccgc
      301 agccatcaga ccggtgtaag cggtgaaaat aacagcgtcc gtctcagcat tcagggcggt
      361 catctcggtc acgataacaa cggcggtatt gcccgtggag ccacgccgga aagcagcggc
      421 agctatggct tcgtccgtct ggagggtgac ctgctcagaa cagaggttgc cggtatgtct
      481 gtgaccgcgg gggtatatgg tgctgctggc cattcttccg ttgatgttaa ggatgatgac
      541 ggctcccgtg ccggcacggt ccgggatgat gccggcagcc tgggcggata cctgaatctg
      601 atacacaacg cctccggcct gtgggctgac attgtggccc agggaacccg ccacagcatg
      661 aaagcctcat cggacaataa cgacttccgc gtccggggct ggggctggct gggttcgctg
      721 gaaaccggtc tgcccttcag tatcactgac aatctgatgc tggagccgca actgcagtac
      781 acctggcagg gactctccct ggatgacggc caggataacg ccggttatgt gaagttcggg
      841 catggcagtg cacaacatgt gcgtgccggc ttccgtctgg gcagccacca cgatatgaac
      901 tttggtaaag gcacctcatc ccgtgacacc ctgcgcggca gtgccaaaca cagtgtgcgt
      961 gaactgccgg tgaactggtg ggtacagcct tctgttatcc gcaccttcag ctcccgggga
     1021 gatatgcgtg tggggacttc cactgcaggc agcgggatga cgttctctcc ctcacagaat
     1081 ggtacgtcac tggacctgca ggccggactg gaagcccgtg tccgggaaaa tatcaccctg
     1141 ggcgttcagg caggttatgt ccacagcgtc agcggcagca gcgctgaagg ctataacggt
     1201 caggccacgc tgaatgtgac cttctgacag aaccatcgcc tctctgtggt cccggtcatc
     1261 atgatcggga cccggaccgg cgcaacggat
//
LOCUS       DADXDL010000271         1290 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.281, whole genome shotgun sequence.
ACCESSION   DADXDL010000271 DADXDL010000000
VERSION     DADXDL010000271.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.281"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..1227
                     /gene="ag43"
                     /locus_tag="IRB70_005015"
     CDS             <1..1227
                     /gene="ag43"
                     /locus_tag="IRB70_005015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HBC0634798.1"
                     /translation="GRATGKTILNLVNAGNSASGLATSGKGIQVVEAINGATTEEGAF
                     VQGNRLQAGAFNYSLNRDSDESWYLRSENAYRAEVPLYASMLTQAMDYDRIVAGSRSH
                     QTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESSGSYGFVRLEGDLMRTEVAGMS
                     VTAGVYGAAGHSSVDVKDDDGSRVGTVRDDAGSLGGYLNLIHNASGLWADIVALGTRH
                     SMKASTDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGKDNAGY
                     VKFGHGSAQHVRAGFRLGSHNDMTFGEGTSSRAPLRDSAKHSVSELPVNWWVQPSVIR
                     TFSSRGDMRVGTSTAGSGMTFSPSQNGTSLDLQAGLEARVRENITLGVQAGYAHSVSG
                     SSAEGYNGQATLNVTF"
BASE COUNT          277 a          356 c          402 g          255 t
ORIGIN      
        1 ggcagggcaa ccggaaaaac catcctgaac ctggtgaacg ccggcaacag tgcgtcgggg
       61 ctggcgacca gcggtaaggg tattcaggtg gttgaagcca ttaacggtgc caccacggag
      121 gaaggggcct ttgtccaggg gaacaggctg caggccggtg cctttaacta ctccctcaac
      181 cgggacagtg atgagagctg gtatctgcgc agtgaaaatg cttatcgtgc agaagtcccc
      241 ctgtatgcct ccatgctgac acaggcaatg gactatgacc ggattgtggc aggctcccgc
      301 agccatcaga ccggtgtaaa tggtgaaaac aacagcgtcc gtctcagcat tcagggcggt
      361 catctcggtc acgataacaa tggcggtatt gcccgtgggg ccacgccgga aagcagcggc
      421 agctatggat tcgtccgtct ggagggtgac ctgatgagaa cagaggttgc cggtatgtct
      481 gtgaccgcgg gggtatatgg tgctgctggc cattcttccg ttgatgttaa ggatgatgac
      541 ggctcccgtg tcggcacggt ccgggatgat gccggcagcc tgggcggata cctgaatctg
      601 atacacaacg cctccggact gtgggctgac attgtggccc tgggaacccg ccacagcatg
      661 aaagcgtcaa cggacaataa cgacttccgc gcccggggtt ggggctggct gggttcactg
      721 gaaaccggtc tgcccttcag tatcactgac aacctgatgc tggagccaca actgcagtat
      781 acctggcagg gactttccct ggatgacggt aaggacaacg ccggttatgt gaagttcggg
      841 catggcagtg cacaacatgt gcgtgccggt ttccgtctgg gcagccacaa cgatatgacc
      901 tttggcgaag gcacctcatc ccgtgccccc ctgcgtgaca gtgcaaaaca cagtgtgagt
      961 gaattaccgg tgaactggtg ggtacagcct tctgttatcc gcaccttcag ctcccgggga
     1021 gatatgcgtg tggggacttc cactgcaggc agcgggatga cgttctctcc ctcacagaat
     1081 ggcacatcac tggacctgca ggccggactg gaagcccgtg tccgggaaaa tatcaccctg
     1141 ggcgttcagg ccggttatgc ccacagcgtc agcggcagca gcgctgaagg gtataacggt
     1201 caggccacac tgaatgtgac cttctgacag aaccatcgcc tctctgtggt cccggtcatc
     1261 atgaccggga cccggaccgg cgcaacggat
//
LOCUS       DADXDL010000272         1253 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.282, whole genome shotgun sequence.
ACCESSION   DADXDL010000272 DADXDL010000000
VERSION     DADXDL010000272.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1253)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1253)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1253
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.282"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            359..499
                     /locus_tag="IRB70_005016"
     CDS             359..499
                     /locus_tag="IRB70_005016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004031751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634799.1"
                     /translation="MAESGYGLAGLGMGKVKSINQYRLTPGFGGFTPVSYETTECRLP
                     CR"
     gene            597..1250
                     /locus_tag="IRB70_005017"
     CDS             597..1250
                     /locus_tag="IRB70_005017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001757010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBC0634800.1"
                     /translation="MIQTRNQYLQFMLVMLAAWGISWGARFVMEQAVLLYGSGKNYLF
                     FSHGTVLMYLLCVFLVYRRWIAPLPVVGQLRNVGVPWLVGAMAVVYVGVFLLGKALAL
                     PAEPFMTKLFADKSIPDVILTLLTIFILAPLNEETLFRGIMLNVFRSRYCWTMWLGAL
                     ITSLLFVAAHSQYQNLLTLAELFLVGLITSVARIRSGGLLLPVLLHMEATTLGLLFG"
BASE COUNT          282 a          318 c          335 g          318 t
ORIGIN      
        1 tgtcctatgg acagacagat atgcacctcc caccgtaaac ggcgggcccc aaccggagcc
       61 actttagtta caacacacaa aaccaacctc cagaaaaacc ccgaaccagc gcagaactga
      121 aaccacaaag cccctccctc ataactgaaa agcggccccg ccccggccca aagggccgga
      181 acagagtcgc ttttaattat gaatgttgta actacatctt catcgctgtc agtcttctcg
      241 ctggaagttc tcagtacacg ctcgtaagcg gccctcacgg cccgctaacg cggagatacg
      301 ccccgacttc gggtaaaccc tcgtcgggac cactccgacc gcgcacagaa gctctctcat
      361 ggctgaaagc gggtatggtc tggcagggct ggggatgggt aaggtgaaat ctatcaatca
      421 gtaccggctt acgccgggct tcggcggttt tactcctgta tcatatgaaa caacagagtg
      481 ccgccttcca tgccgctgat gcggcatatc ctggtaacga tatctgaatt gttatacatg
      541 tgtatatacg tggtaatgac aaaaatagga caagttaaaa atttacaggc gatgcaatga
      601 ttcaaacacg taatcaatat ctgcagttta tgctggttat gctggctgca tggggcatta
      661 gttggggagc cagatttgtc atggagcagg ccgttctgct ttatggatca ggaaaaaact
      721 atttgttctt cagtcatggt actgttctga tgtacctgct gtgtgttttc ctggtatacc
      781 gccgttggat agctccgcta ccggtcgttg gtcagctgcg caacgttggc gtaccgtggc
      841 tggtcggtgc gatggccgtg gtgtatgtcg gtgtatttct gctcggtaag gcgctggctc
      901 tgcctgctga gccatttatg acgaaacttt ttgccgataa gtccatacct gacgtgatcc
      961 tgacgttgct gaccatcttt atccttgccc cgttgaatga ggaaacgctg ttccggggga
     1021 ttatgctgaa cgtcttccgt tcacggtact gctggacgat gtggctgggg gcgctgataa
     1081 cgtcgttgtt gttcgtcgcc gcgcacagcc agtatcagaa cctgctgaca ctggcagaac
     1141 tgttcctggt ggggttgatt acatcagtgg ccaggatcag aagtggtggc ctgctgctgc
     1201 cggtattgct gcatatggaa gcaaccacgc tgggtttact gtttggttga aag
//
LOCUS       DADXDL010000273         1244 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.283, whole genome shotgun sequence.
ACCESSION   DADXDL010000273 DADXDL010000000
VERSION     DADXDL010000273.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1244
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.283"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            176..1156
                     /locus_tag="IRB70_005018"
     CDS             176..1156
                     /locus_tag="IRB70_005018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110-like element IS621 family transposase"
                     /protein_id="HBC0634801.1"
                     /translation="MEHELHYIGIDTAKEKLDVDVLRPDGRHRTKKFANTTKGHDELV
                     SWLKGHKIDHAHICIEATGTYMEPVAECLYDAGYIVSVINPALGKAFAQSEGLRNKTD
                     TVDARMLAEFCRQKRPAAWEAPHPLERALRALVVRHQALTDMHTQELNRTETAREVQR
                     PSIDAHLLWLEAELKRLEKQIKDLTDDDPDMKHRRKLLESIPGIGEKTSAVLLAYIGL
                     KDRFAHARQFAAFAGLTPRRYESGSSVRGASRMSKAGHVSLRRALYMPAMVATSKTEW
                     GRAFRDRLAANGKKGKVILGAMMRKLAQVAYGVLKSGVPFDASRHNPVAA"
BASE COUNT          306 a          304 c          370 g          264 t
ORIGIN      
        1 tgcagagaaa atcggccagt tttctctgcc tgcagtccgc atgccgtatc gggccttggg
       61 ttctaacctg ttgcgtagat ttatgcagcg gactgccttt ctcccaaagt gataaaccgg
      121 acagtatcat ggaccggttt tcccggtaat ccgtatttgc aaggttggtt tcactatgga
      181 acatgaactt cattatatcg gtatcgacac cgctaaagag aaactggatg tcgatgtgtt
      241 gcgtcctgat ggtcgtcatc gcaccaaaaa attcgctaac accactaaag ggcacgatga
      301 gctggtgagc tggctgaaag gtcacaagat tgaccatgcg catatctgca tcgaagcgac
      361 cggcacctat atggaacctg tcgctgagtg cctttacgat gctggctaca tagtgtcagt
      421 cattaatcct gcgctgggta aagctttcgc tcagagtgaa ggactgcgta acaagactga
      481 taccgtggat gcgcgcatgc tggcagagtt ctgtcgtcag aagcgccctg cagcctggga
      541 agcgcctcac ccgcttgaac gcgcgttgcg tgccctggta gtccgccacc aggcgctgac
      601 agatatgcac acgcaggaac tgaatcgcac tgaaacggcg cgggaagtcc agagaccgag
      661 cattgatgct caccttctgt ggcttgaagc agagctgaag cgtcttgaga agcagataaa
      721 agacctgaca gacgatgatc cggatatgaa acaccgcagg aaactgctgg aaagcatccc
      781 gggtatcgga gagaaaacat ctgcggtatt gctggcttat atcggtctga aggaccgctt
      841 cgcccatgcc agacagttcg ccgcttttgc gggtctgaca ccacggcgtt atgaatcagg
      901 tagcagtgtg agaggggcga gccggatgag taaggccgga catgtgtcgc ttcgcagggc
      961 gttgtatatg cccgcaatgg tagccaccag taagactgag tggggacggg cgttccgcga
     1021 ccgtctggcg gctaatggca agaaaggaaa ggtgattctc ggcgcgatga tgcgcaagct
     1081 ggcacaggtg gcgtatggag tgctgaagtc aggcgtgccg ttcgatgcgt cacggcataa
     1141 tccggtagcg gcgtaaaaat cgcggaaggg atgaaaaaaa cagcgcctga cggcgctgtg
     1201 tctggcatgc ctgcaatcag ggaaaccgga ccaggaaaaa actt
//
LOCUS       DADXDL010000274         1233 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.285, whole genome shotgun sequence.
ACCESSION   DADXDL010000274 DADXDL010000000
VERSION     DADXDL010000274.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1233
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.285"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..113
                     /locus_tag="IRB70_005019"
     CDS             <1..113
                     /locus_tag="IRB70_005019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HBC0634802.1"
                     /translation="ILTNDKVFKAGLRRKMRKAAMDRNYLTSVLAGSGLS"
     gene            91..228
                     /locus_tag="IRB70_005020"
                     /pseudo
     CDS             91..228
                     /locus_tag="IRB70_005020"
                     /inference="COORDINATES: protein motif:HMM:TIGR03696.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            220..384
                     /locus_tag="IRB70_005021"
                     /pseudo
     CDS             220..384
                     /locus_tag="IRB70_005021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001328206.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
     gene            388..666
                     /locus_tag="IRB70_005022"
                     /pseudo
     CDS             388..666
                     /locus_tag="IRB70_005022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001348663.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretion protein Rhs"
     gene            755..1192
                     /locus_tag="IRB70_005023"
     CDS             755..1192
                     /locus_tag="IRB70_005023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000763815.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634803.1"
                     /translation="MADKAILWALISASTQEGRKACSLSYFSCKAAEAELGLAYMAAN
                     DNKAFLTSLSRIMMYKIDAGLSESYTCYLLSKGKIIRPYLKNLNPHQLVADCIETVNK
                     IKDKNKKIIDIDSVNICNDNKNINWRVNSTIVAIDDSIKCIDE"
BASE COUNT          411 a          203 c          249 g          370 t
ORIGIN      
        1 atattttgac gaatgataag gtattcaagg cagggttaag acgtaagatg cgaaaagcag
       61 ccatggacag aaactatctg acgtcagtcc ttgctgggag cgggctttcg taatctttcc
      121 ctgctgcagg ggcggtatat cactcaggat ccgattgggc tgaagggggg atggaatttt
      181 tatcagtatc cgttgaatcc gataactgat attgacccgt tgggattagc gacctgttta
      241 tacagcataa ctttaggtat gctttcatgc gtttcagata cgtcaagtga tgataattct
      301 tatggtgtgc ttactatttc agtcgcctct ggtaataatg gtaataatat gcaatgtaaa
      361 aataatcctg gttgtacaca cttacaaaat agaggcccaa tacctcaagg ggtatggagc
      421 tggaatgtta atggtcctgg agcaactaat agaaaaccta atggtatacg tttagtaccg
      481 tcagcaaata cagaaacgta taatcgtgat ggatttttaa cacatagttg tttaaacgct
      541 tttggtccat ctttaggacc tcgattctgt tccgaggggt gtataactgg ttcatctaat
      601 gacatgcaaa aattaaatga gctaatattt tcagagccag atagcacatt aacagtgacg
      661 gactagaaat atggcaaggt tattaacaat tgtgcttttt ttctctattt ctgcgaatgc
      721 agttactgta aaccaatttc agagagagtt ggatttggca gacaaggcaa tattatgggc
      781 actaatatca gccagtaccc aagagggacg aaaagcgtgt tcacttagct atttttcatg
      841 taaagccgca gaggctgaac tcggactggc atatatggct gctaatgata acaaggcatt
      901 tctcacatcc ttatctagaa taatgatgta caaaatagat gctggacttt ccgaatccta
      961 tacatgctat ttattaagca agggaaagat cataagacca tatctgaaga atctaaatcc
     1021 acaccaactt gtcgctgatt gcattgaaac tgtaaataaa ataaaagata aaaataaaaa
     1081 aatcattgat atagattcag ttaatatttg caatgataat aaaaatataa attggagagt
     1141 taatagtact attgtagcca ttgatgattc tataaaatgc atcgatgaat aataacttaa
     1201 ttatatttaa aaatatatta ataactcact ctc
//
LOCUS       DADXDL010000275         1198 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.286, whole genome shotgun sequence.
ACCESSION   DADXDL010000275 DADXDL010000000
VERSION     DADXDL010000275.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1198)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1198)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1198
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.286"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..969
                     /locus_tag="IRB70_005024"
     CDS             <1..969
                     /locus_tag="IRB70_005024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004389801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30-like element IS30 family transposase"
                     /protein_id="HBC0634804.1"
                     /translation="SEREEIRAGLSAKMSIRAIATALNRSPSTISREVQRNRGRRYYK
                     AVDANNRANRMAKRPKPCLLDQNLPLRKLVLEKLEMKWSPEQISGWLRRTKPRQKTLR
                     ISPETIYKTLYFRSREALHHLNIQHLRRSHSLRHGRRHTRKGERGTINIVNGTPIHER
                     SRNIDNRRSLGHWEGDLVSGTKNSHIATLVDRKSRYTIILRLRGKDSVSVNQALTDKF
                     LSLPSELRKSLTWDRGMELARHLEFTVSTGVKVYFCDPQSPWQRGTNENTNGLIRQYF
                     PKKTCLAQYTQHELDLVAAQLNNRPRKTLKFKTPKEIIERGVALTD"
     gene            976..1198
                     /locus_tag="IRB70_005025"
                     /pseudo
     CDS             976..1198
                     /locus_tag="IRB70_005025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611997.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT          388 a          269 c          280 g          261 t
ORIGIN      
        1 tctgagcgcg aggagatacg agctggtttg tcagccaaaa tgagcattcg tgcgatagct
       61 actgcgctga atcgcagtcc ttcgacgatc tcacgtgaag ttcagcgtaa tcggggcaga
      121 cgctattaca aagctgttga tgctaataac cgagccaaca gaatggcgaa aaggccaaaa
      181 ccgtgcttac tggatcaaaa tttaccattg cgaaagcttg ttctggaaaa gctggagatg
      241 aaatggtctc cagagcaaat atcaggatgg ttaaggcgaa caaaaccacg tcaaaaaacg
      301 ctgcgaatat cacctgagac aatttataaa acgctgtact ttcgtagccg tgaagcgcta
      361 caccacctga atatacagca tctgcgacgg tcgcatagcc ttcgccatgg caggcgtcat
      421 acccgcaaag gcgaaagagg tacgattaac atagtgaacg gaacaccaat tcacgaacgt
      481 tcccgaaata tcgataacag acgctctctg gggcattggg agggcgattt agtctcaggt
      541 acaaaaaact ctcatatagc cacacttgta gaccgaaaat cacgttatac gatcatcctt
      601 agactcaggg gcaaagattc tgtctcagta aatcaggctc ttaccgacaa attcctgagt
      661 ttaccgtcag aactcagaaa atcactgaca tgggacagag gaatggaact ggccagacat
      721 ctagaattta ctgtcagcac cggcgttaaa gtttacttct gcgatcctca gagtccttgg
      781 cagcggggaa caaatgagaa cacaaatggg ctaattcggc agtactttcc taaaaagaca
      841 tgtcttgccc aatatactca acatgaacta gatctggttg ctgctcagct aaacaacaga
      901 ccgagaaaga cactgaagtt caaaacaccg aaagagataa ttgaaagggg tgttgcattg
      961 acagattgaa tctacaacag cgtattttgc acaggagtcg ctgaaaaata cgcgttaatc
     1021 gaacaatggc gacaacaatt tcccattgaa gcgatgtgtc aggtatttgg tgtatccagg
     1081 agcggttatt acaactgggt acagcatgaa ccctcagaca gaaaacaaag tgatgagcgg
     1141 ctaaaactgg agattaaggt ggcacatatc cgcactcgcg aaacatatgg aacccggc
//
LOCUS       DADXDL010000276         1196 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.287, whole genome shotgun sequence.
ACCESSION   DADXDL010000276 DADXDL010000000
VERSION     DADXDL010000276.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1196)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1196)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1196
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.287"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..759
                     /locus_tag="IRB70_005026"
     CDS             <1..759
                     /locus_tag="IRB70_005026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001314987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III secretion protein"
                     /protein_id="HBC0634805.1"
                     /translation="EIVAGSILQLLRQAQDSQFPTFGKKNGQMKSIDNKSSLQVDRNS
                     SFSLQTNGIEQLSTKKVLNMTSRYQGVNSELSDKAIQFKGEIHNGIHTENITVQNHSN
                     NKEREKKYRDGDKKNGEQAHLLDITNERRFADNKIMFTQHIEKQRNVHTLNQNDINNS
                     VNSANVPENELTYQFQRWGQNHTVRILESSEGIRLKPSDTIVSDRLHEAQHNDVTAQR
                     WVLTEQDERQGQRHQPHDEQENEGKFENDQKDES"
     gene            759..>1196
                     /locus_tag="IRB70_005027"
     CDS             759..>1196
                     /locus_tag="IRB70_005027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001578916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YscQ/HrcQ family type III secretion apparatus
                     protein"
                     /protein_id="HBC0634806.1"
                     /translation="MFGLRKVNGNTHSFETTFQNWKEKGEDVALLMPEFSAKWLPIAE
                     ESGSWSGWVLLREIFPLISAELAGMALMPETERLIGEWLSLTSSPLNLEYPELKYNRL
                     CVGKVFDGVLSSAQPLIRIWTGELNLWLDKVTVCQYENAPTLDK"
BASE COUNT          426 a          211 c          260 g          299 t
ORIGIN      
        1 gagattgttg ctggatccat tctccagtta ttacgtcagg ctcaggatag ccaattccct
       61 acgtttggga aaaagaatgg gcaaatgaag tctattgata acaaatcgtc tctccaggtt
      121 gacaggaatt catctttttc tttgcaaaca aatggaatag agcaactttc tacaaagaaa
      181 gtcctcaata tgacttcacg atatcagggt gttaattctg aactatctga taaagcgata
      241 caatttaagg gggaaatcca taatggtatc catacagaaa acatcacggt tcaaaaccac
      301 agtaataata aagagcgtga aaaaaaatat cgcgatggag acaaaaaaaa tggagagcag
      361 gcccatttat tagatattac taacgaaaga aggtttgctg ataacaaaat catgtttact
      421 caacatatcg aaaagcaaag gaatgttcat acgctcaatc agaatgatat aaataattct
      481 gttaatagtg ccaatgtacc cgaaaatgaa ttgacatatc agtttcagcg ttggggacag
      541 aatcatacag ttcggattct ggaaagtagt gaagggatac gactaaaacc atcagacacg
      601 attgtctccg acagactcca tgaagcccaa cacaatgatg ttacagcaca acgttgggta
      661 ttgactgagc aagatgaacg acaagggcaa cgacatcagc ctcatgatga gcaagaaaat
      721 gaaggtaaat tcgaaaacga tcagaaggac gaaagttaat gttcggtctg agaaaagtaa
      781 atggaaacac tcattccttt gaaaccactt ttcaaaactg gaaagaaaag ggtgaagatg
      841 ttgcgttatt aatgcccgaa tttagcgcca aatggctacc gatagcagaa gagagcggca
      901 gctggtctgg atgggtgtta cttcgagaaa tatttccctt aatttctgcc gagctcgctg
      961 ggatggcttt aatgccagaa acggaaaggt taatagggga atggctcagt ttaaccagtt
     1021 ccccgttaaa tctagagtat cctgaactaa aatataatcg tttgtgcgta ggtaaagtat
     1081 ttgatggagt attgagttca gctcaaccac tgataagaat atggacaggg gaattgaatc
     1141 tttggttaga taaagtcaca gtctgccaat acgaaaacgc tccaacgtta gacaaa
//
LOCUS       DADXDL010000277         1143 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.288, whole genome shotgun sequence.
ACCESSION   DADXDL010000277 DADXDL010000000
VERSION     DADXDL010000277.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.288"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1..1143
                     /locus_tag="IRB70_005028"
                     /pseudo
     CDS             1..1143
                     /locus_tag="IRB70_005028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611435.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS2 family transposase"
BASE COUNT          282 a          284 c          343 g          234 t
ORIGIN      
        1 ccggagaaac gcagacggcg taccacacag gaaaagatcg caattgttca gcagagcttt
       61 gaaccgggga tgacggtctc cctcgttgcc cggcaacatg gtgtagcagc cagccagtta
      121 tttctctggc gtaagcaata ccaggaagga agtcttactg ctgtcgccgc cggagaacag
      181 gttgttcctg cctctgaact tgctgccgcc atgaagcaga ttaaagaact ccagcgcctg
      241 ctcggcaaga aaacgatgga aaatgaactc ctcaaagaag ccgttgaata tggacgggca
      301 aaaaagtgga tagcgcacgc gcccttattg cccggggatg gggagtaagc ttagtcagcc
      361 gttgtctccg ggtgtcgcgt gcgcagttgc acgtcattct cagacgaacc gatgactgga
      421 tggatggccg ccgcagtcgt cacactgatg atacggatgt gcttctccgt atacaccatg
      481 ttatcggaga gctgcccacg tatggttatc gtcgggtatg ggcgctgctt cgcagacagg
      541 cagaacttga tggtatgcct gcgatcaatg ccaaacgtgt ttaccggatc atgcgccaga
      601 atgcgctgtt gcttgagcga aaacctgctg taccgccatc gaaacgggca catacaggca
      661 gagtggccgt gaaagaaagc aatcagcgat ggtgctctga cgggttcgag ttctgctgtg
      721 ataacggaga gagactgcgt gtcacgttcg cgctggactg ctgtgatcgt gaggcactgc
      781 actgggcggt cactaccggc ggcttcaaca gtgaaacagt acaggacgtc atgctgggag
      841 cggtggaacg ccgcttcggc aacgatcttc cgtcgtctcc agtggagtgg ctgacggata
      901 atggttcatg ctaccgggct aatgaaacac gccagttcgc ccggatgttg ggacttgaac
      961 cgaagaacac ggcggtgcgg agtccggaga gtaacggaat agcagagagc ttcgtgaaaa
     1021 cgataaagcg tgactacatc agtatcatgc ccaaaccaga cgggttaacg gcagcaaaga
     1081 accttgcaga ggcgttcgag cattataacg aatggcatcc gcatagtgcg ctgggttatc
     1141 gct
//
LOCUS       DADXDL010000278         1143 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.289, whole genome shotgun sequence.
ACCESSION   DADXDL010000278 DADXDL010000000
VERSION     DADXDL010000278.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1143)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1143)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1143
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.289"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>1143
                     /locus_tag="IRB70_005029"
     CDS             join(<1..237,237..>1143)
                     /locus_tag="IRB70_005029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612262.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBC0634807.1"
                     /translation="FTPEFRLECAQLIVDKGYSYRQASEAMNVGSTTLESWVRQLRRE
                     RQGIAPSATPITPEQQRIRELEKQVRRLEEQNTIFKKGYRALDVRLTERFTIVSRLSD
                     SHSVVSLCSALGIHRSSYRYWRKRRDTVNSARVRLCSEIRRAWNQSRGSAGARTLAEM
                     LTQNGVPMSRYRAGRLMKYLNLSSCQPGKHQYKNACQEHTCLPNLLERQFAVPEPDRV
                     WCGDITYIWAGNRWCYLAVVMDLFARRVIGWSLSANADTALISSALRMAYEVRGQPRD
                     VMFHSDQGSQYTGLKYQQLLWRYRIKQSVSRRGNCWDNSPMERFFRSLKTEWVPTDGY
                     VGKDEARQQISGYILNYYNSVRPHHYNGGLTPEESENRYRFYCKTVA"
BASE COUNT          289 a          280 c          328 g          246 t
ORIGIN      
        1 ctttcacccc tgagttcagg ctggaatgtg cacagctgat tgttgataag ggctattcgt
       61 atcgacaagc cagtgaggcg atgaatgtcg gttctaccac gcttgagagc tgggtacgtc
      121 agctcaggcg agagcgccaa ggtattgcgc cctctgcaac acccattacc cctgaacagc
      181 aacgtattcg cgagctggaa aagcaggttc gccgactgga ggaacaaaat acgatattaa
      241 aaaaggctac cgcgctcttg atgtccgact cactgaacgg tttacgatag tttccagact
      301 gagtgacagc cactcagttg tcagcctctg ttccgcactg ggaatacacc gtagcagtta
      361 ccggtactgg cgaaaacgac gcgatacggt taattcggct cgcgtcaggt tgtgcagcga
      421 aatacgccgg gcatggaacc agagccgggg ctctgcaggc gcgcgcacgc tggctgaaat
      481 gctgacccaa aacggcgtcc cgatgagccg ttatcgtgcc ggacggctga tgaaatacct
      541 gaacctgagc agttgtcagc ccggaaaaca tcaatacaaa aatgcctgtc aggagcatac
      601 gtgtttgccg aatctgctcg agcgtcagtt cgctgtaccg gagccagaca gggtatggtg
      661 cggagatatt acgtatatct gggcaggaaa tcgctggtgc tatctggcgg tcgtcatgga
      721 tctttttgcc cgcagggtta tcggctggag cctgtcagcg aatgccgata ctgcactgat
      781 aagcagtgcc ttgcggatgg cgtatgaggt gcgtggtcag ccgcgggacg tcatgttcca
      841 tagcgaccag ggaagtcagt atacaggact gaaatatcaa cagcttctct ggcgttacag
      901 gataaagcaa agtgtcagcc gacggggaaa ctgctgggat aacagtccta tggaacgctt
      961 cttccgcagt ctgaaaacag aatgggtgcc gacggatggt tacgtaggca aggacgaggc
     1021 ccggcaacaa attagcggtt atatcctgaa ttattacaat agcgtcaggc ctcaccatta
     1081 caacggtggg ttgacgccgg aagaatcaga gaacagatac cgtttttact gtaaaaccgt
     1141 ggc
//
LOCUS       DADXDL010000279         1094 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.290, whole genome shotgun sequence.
ACCESSION   DADXDL010000279 DADXDL010000000
VERSION     DADXDL010000279.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1094)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1094)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1094
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.290"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(164..677)
                     /locus_tag="IRB70_005030"
                     /pseudo
     CDS             complement(164..677)
                     /locus_tag="IRB70_005030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001566943.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4113 domain-containing protein"
     gene            complement(738..842)
                     /locus_tag="IRB70_005031"
                     /pseudo
     CDS             complement(738..842)
                     /locus_tag="IRB70_005031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000544830.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
     gene            complement(844..1094)
                     /locus_tag="IRB70_005032"
                     /pseudo
     CDS             complement(844..1094)
                     /locus_tag="IRB70_005032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          241 a          284 c          246 g          323 t
ORIGIN      
        1 gctttttcgg ttgaaaagaa attgattgaa ttactggaaa aacaatctgg tctccatacg
       61 tctgtggatt gcagtactcc ccttacagag cagagtctgt cgagaaatga cggtgaagac
      121 cagaccagaa gaaacgctga aaatatgttc ggagatgact gaactaaccc agcctggcca
      181 ggggaatatc tcgccattta gttgtataac actgactcaa catttcccgt ttcatttgcc
      241 attcaggggc ggttcctcgc cccgcaaacc acactttccc ttttcccgac tggttcagtt
      301 catcgagtgt tttcattaac ttttcactgt ttttacgggg ctggatttca tcaaataatc
      361 ccggctgcgc tatacccgat ggtgtgaaat cagccagcat gactcctgcc ttcatatagc
      421 ggtacccttc acgccagaca tggtttaagg ctctgcatgc ggcggcaata atgtcccggc
      481 tgtcctgtgt gggcaatgaa agcttttcca cagcggcatt gctgtaacag ggttcagggg
      541 gatgtccgta caaatgtcgt cacctgccgg caatactgac tctccccacg tagtttctct
      601 gcggcccgct ctgcatactg aacaacagcc tggtgcatgg catctttgtc tgtgattcgt
      661 tcaccaaaac tgcgactatg tcaacgccac gatgtttgac cgttatttgc cattttcatg
      721 cccgctaaat actttcgtta ctgatgctgt ccgctttgca ccatttcatc atcactgatt
      781 ggcgttgtgt ttttggtcag cactccagct ttacgtttct cttttaaccg gtaactctct
      841 ccttgttctt tttgacggac gcattttacg tttgggctgg atgtagtaac gcagcatgga
      901 acgtccgccc gtataaccca ttgccttaat ctccgcgaag ataacctcgc tattccagac
      961 attctctgcc aggcgcatgt cgatgtaatc cataaacggt ttcagcttaa ccattttgtg
     1021 gcgggtcttt ctggctggcg gttcagggta tttgaggtag cgtctgaccg tccgttcaga
     1081 gcaaccaatc tgag
//
LOCUS       DADXDL010000280         1085 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.291, whole genome shotgun sequence.
ACCESSION   DADXDL010000280 DADXDL010000000
VERSION     DADXDL010000280.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1085)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1085)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1085
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.291"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..485
                     /locus_tag="IRB70_005033"
     CDS             <1..485
                     /locus_tag="IRB70_005033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Ail/Lom family outer membrane beta-barrel
                     protein"
                     /protein_id="HBC0634808.1"
                     /translation="TDMPGSDDLKGINVKYRYEFTDTLGLVTSFSYANAKDEQKTHYS
                     DTRWHEDSVRNRWFSMMAGPSVRVNEWFSAYAMAGVAYSRVSTFSGDYLRVTDNKGKT
                     HDVLTGSDDDRHSNTSLAWGAGVQFNPTESVAIDIAYEGSGSGDWRTDGFIVGVGYKF
                     "
     gene            550..>1085
                     /locus_tag="IRB70_005034"
     CDS             550..>1085
                     /locus_tag="IRB70_005034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HBC0634809.1"
                     /translation="MAAVKISGVLKDGAGKPIQNCTIQLKAKRNSTTVLVNTVASENP
                     DEAGRYSMDVEYGQYSVTLLVEGFPPSHAGTITVYEGSRPGTLNDFLGAMTEDDVMPE
                     ALRRFEAMVEEAARNAEAASQSAAVAKKSETAAASSKNAAKTSETNAANSAQAAASSQ
                     TASANSATAAKKSETNAK"
BASE COUNT          288 a          258 c          316 g          223 t
ORIGIN      
        1 atactgatat gccaggcagt gatgacctga agggcattaa cgtgaaatac cgttatgaat
       61 ttacggacac gctggggctg gtgacgtcat tcagttatgc caatgccaaa gatgagcaaa
      121 aaacgcatta cagcgatacc cgctggcatg aagattcagt gcgtaaccgc tggttcagca
      181 tgatggcggg gccatctgta cgcgtgaatg aatggttcag tgcttatgcg atggcaggtg
      241 tggcttacag ccgtgtttcg acgttctccg gggattatct ccgcgtaact gacaacaagg
      301 ggaaaacgca cgatgtgctg accggaagtg atgacgatcg ccacagcaac acgtctctgg
      361 cgtggggagc tggcgtgcag tttaacccga ccgaatccgt ggccattgat attgcttatg
      421 aaggctccgg cagtggcgac tggcgcactg acggtttcat cgtgggtgtc ggttataaat
      481 tctgattagc caggtaacac agtgttatga cagcccgccg gttcaggcgg gcttttttgt
      541 ggagtggata tggcagcagt aaaaatctca ggtgtgctga aagatggtgc gggaaaacca
      601 atacagaact gcactattca actgaaggca aagcgtaaca gcaccacggt actggtgaac
      661 acggtggcct ctgaaaatcc ggatgaagcc gggcgttaca gcatggatgt tgagtatggc
      721 cagtacagcg tcaccctgct ggttgaaggt tttccgcctt cacatgccgg aaccattacc
      781 gtctatgaag gttccagacc aggtacgctg aatgattttc tcggtgccat gacggaagat
      841 gatgtcatgc cggaggcatt gcgtcgtttt gaggcaatgg tggaagaagc ggcacgcaac
      901 gccgaagccg cctctcagag cgcagcggtg gcaaagaaat ccgaaactgc agcggcatca
      961 tcgaagaacg cggcgaaaac ctcagaaacg aatgcagcta acagcgcaca ggcggcagcg
     1021 tcctcgcaga ctgcatcggc aaactccgcg acagcagcca aaaaatcaga aaccaacgcg
     1081 aaaaa
//
LOCUS       DADXDL010000281         1079 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.292, whole genome shotgun sequence.
ACCESSION   DADXDL010000281 DADXDL010000000
VERSION     DADXDL010000281.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1079)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1079)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1079
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.292"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>1079)
                     /locus_tag="IRB70_005035"
     CDS             complement(<1..>1079)
                     /locus_tag="IRB70_005035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HBC0634810.1"
                     /translation="VTSQTAGISAVTASINNSSQSRNVTFIADVSTAQIASLEVTQDN
                     AVADGAMANTLLVRVTDAFGNTLAGQTVSVLADTGTTVAPTVITGLDGTVEISVTSQT
                     AGTSAVTASINSSTASRNVTFVADVRTAKIADLVVIKDGSVADGAMANTLRVKITDAF
                     GNTLAGQTVSVLADNGATTAPTVTTQPDGTVEISVTSQTAGISAVTATINNSTASQNV
                     MFIADVRTAKIADLVVTRDNSVADGAMANTLQVKVTDANGNTLAGQTVSVLADNSATT
                     APTVITEPDGMVEISVTSQTAGTSAVTASINNSSLSQSVKFIADVSTAQIAMLEVTQD
                     NAVADGAMANTLQVKVTDAFGNALSG"
BASE COUNT          173 a          357 c          296 g          253 t
ORIGIN      
        1 ccggaaagtg cattcccgaa cgcatcggtc accttcacct gcaacgtgtt cgccattgcg
       61 ccgtctgcca ccgcgttatc ctgcgtcacc tccagcatcg cgatctgcgc cgtgctgaca
      121 tcggcaataa acttcacgct ctggctcagg ctgctgttgt tgatgctggc ggtgaccgca
      181 ctggtgcccg ccgtctggct ggtgacactg atctccacca taccgtccgg ctctgtgatt
      241 accgtcgggg cagtcgttgc gctgttgtcc gccaacacgc tgaccgtctg cccggcaagc
      301 gtattaccgt tagcatcggt aaccttcact tgcagcgtgt tcgccattgc gccgtcagcc
      361 actgagttat cccgggtgac caccagatca gcgatcttcg ccgtcctgac atcggcgata
      421 aacatcacgt tctggctcgc ggtgctgttg ttgatggttg cagtgaccgc actgattccg
      481 gcggtctggc tggtgacact gatttccacc gtgccgtccg gctgcgtggt gaccgtcgga
      541 gcagtcgtgg caccgttgtc cgccaacacg ctgactgtct gcccggcaag cgtattaccg
      601 aatgcatcgg tgatcttcac ccgcagcgtg ttcgccattg cgccgtcagc cactgagcca
      661 tccttaatga ccaccagatc agcgatcttc gccgtcctga catctgcaac aaacgtcacg
      721 ttccggctcg cggtactgct gttgatactg gcggtgaccg cactggtgcc tgccgtctgg
      781 ctggtgacac tgatttccac cgtgccgtcc agccctgtga tgacagtcgg agcgaccgtt
      841 gtgccggtat ccgccaatac gctgaccgtc tgcccggcaa gcgtattacc gaacgcatcg
      901 gtcaccctca ccagcagcgt attcgccatt gcgccgtctg ccacggcgtt atcctgcgtc
      961 acctccagac tcgcgatctg cgccgtgcta acatcggcga taaacgtcac gttccggctc
     1021 tggctgctgt tgttaatgct ggcggtgacc gcactgattc cggcggtctg gctggtgac
//
LOCUS       DADXDL010000282         1075 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.293, whole genome shotgun sequence.
ACCESSION   DADXDL010000282 DADXDL010000000
VERSION     DADXDL010000282.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1075)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1075)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1075
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.293"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>1075
                     /locus_tag="IRB70_005036"
     CDS             <1..>1075
                     /locus_tag="IRB70_005036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706746.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBC0634811.1"
                     /translation="ESHPLLYRHTMGSKIANVIFEKLYSRIDFNKEQYISFIKDAFIH
                     FYDYSRRYAISENIAKDAVTNNIALMSTFYDSDNTSGEVLNNDFTEEESFETALDVEH
                     AIVLGFADDNFETKPVHYQDLLTRFSAFQDTVFNLFPEMHSSHYNDICSVSVDMTKGT
                     QCMIHLMVNEEVFMSLPVPVATMVREDATNLVNLKTLLNDGCFIKYSHFNDVALIKQN
                     ISNLYLSHTIVNESILKKCCFENGSLGDVKITNSNIVNNVFKNVSFRTVKINNVNTHS
                     LKFINCHFFNVDMIRVNFSKCLFHDCSMHGVKIKPWLPVKWTKELINDYLYGCLLSLY
                     SICARDIYNMIAGNNVKVAADAFL"
BASE COUNT          364 a          147 c          200 g          364 t
ORIGIN      
        1 ttgaatcgca cccattatta tacaggcata ctatgggtag taagattgcg aatgtgattt
       61 ttgaaaaatt atacagtcgt attgacttta acaaagagca atatatatcc tttataaagg
      121 atgcgtttat tcatttttat gattatagca ggcgatatgc aattagtgag aatatcgcaa
      181 aagacgctgt aacaaacaat atcgcattga tgagcacttt ttatgacagt gataatacgt
      241 caggtgaggt tttaaataat gattttacag aagaagagtc atttgaaact gcgttagatg
      301 tagagcatgc aatagtgctt ggatttgctg atgataattt tgaaacaaaa cctgttcatt
      361 atcaggattt attaacacga tttagtgcct ttcaagatac cgtgtttaat ttgtttcctg
      421 aaatgcactc ttcgcattac aacgatattt gtagcgtaag tgtggatatg acaaagggaa
      481 cgcaatgcat gatccacttg atggtgaatg aagaagtttt catgtcgttg cctgttccag
      541 ttgccacgat ggtacgtgaa gatgcaacta atttagtcaa tcttaaaaca ctactcaatg
      601 atggttgctt tattaaatat agtcatttta atgacgtggc attaataaag caaaacataa
      661 gtaatctcta tttatcacac actattgtga atgaaagcat attgaaaaaa tgttgttttg
      721 aaaacggcag tttaggtgat gttaaaataa caaatagcaa tatagtaaac aatgtattca
      781 aaaacgtttc gtttagaact gttaaaatta acaatgtgaa tactcattct ttaaaattta
      841 ttaactgcca ttttttcaat gttgatatga taagagttaa tttcagtaaa tgtctttttc
      901 atgactgtag tatgcatggt gtcaagataa aaccatggtt gccagtaaaa tggacaaaag
      961 aattaataaa tgattatttg tatggctgtt tactatctct gtactctatc tgtgcaagag
     1021 atatatataa tatgatcgcc ggtaataacg tgaaggttgc tgcggatgct ttcct
//
LOCUS       DADXDL010000283         1042 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.294, whole genome shotgun sequence.
ACCESSION   DADXDL010000283 DADXDL010000000
VERSION     DADXDL010000283.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1042)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1042)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1042
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.294"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            347..865
                     /locus_tag="IRB70_005037"
     CDS             347..865
                     /locus_tag="IRB70_005037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hcp family type VI secretion system effector"
                     /protein_id="HBC0634812.1"
                     /translation="MPTPCYISITGQTQGNITAGAFTADSVGNIYVQGHEDEMLVQEF
                     LHNVTVPTDPQSGQPAGQRAHKPFIFTVALNKAVPLMYNALASGEMLPTTELHWWRTS
                     VEGKQEHYFTTRLTDSTIVDMKLHMPHCQDPAKREFTQLLEVSLAYRKIEWEHVKSGT
                     SGADDWRAPLEA"
BASE COUNT          288 a          234 c          254 g          266 t
ORIGIN      
        1 taagtgggta tttttaagga atatctcaaa aattatcaaa acgataattc agaaaggata
       61 aatgcaatat ttattcatga ttcagctttg gccattttat ggaggcaata cggactttga
      121 acagttgggt atggttatcc agatatatat tattaactta ttgctgaata agagatttaa
      181 tgattttaaa aatagttttt acgacaaccg taaattctag ctcggtttgt atgtaaaaaa
      241 tactgaaaaa tgatgcggtt ccgtgaagtg agctgcatct gcctgtctgg gattaacggc
      301 aggtcattgt aagtagtaat taaccacgtt aacaaggagt ttacaaatgc caacaccgtg
      361 ttatatctcc atcactggtc agacccaggg aaatattact gcaggtgcat ttaccgctga
      421 ttctgtcggc aacatctatg tgcaggggca cgaagacgag atgctggtgc aggaattcct
      481 gcataacgtt actgtcccga ccgatcctca gtccggccag cctgcgggtc agcgtgctca
      541 caagccgttc atttttaccg tggcgctgaa caaagctgtt ccgctgatgt acaacgcact
      601 ggcctccggc gaaatgctgc caaccactga acttcactgg tggcgtacct ctgtggaagg
      661 caaacaggag cattatttca ccacccgcct gaccgattcg acgattgtcg atatgaaact
      721 gcatatgccg cattgccagg atccggcgaa acgcgagttc acccagttgc tcgaagtttc
      781 actggcctac cgcaaaatag agtgggaaca cgtcaagtct ggcacctccg gtgccgacga
      841 ctggcgcgca ccgctggaag cataagttaa gccaacagca tccggctatc aggccggatg
      901 ctgtttttgt attacgccgt aaaaagaaag gttgtcagta aggggttacg ttcacgggag
      961 atggcggatg ccggaaactt cggcggtagc gtgcctgaat gcaagcgtaa cactgtactg
     1021 tcacagccgc tttaacagcg aa
//
LOCUS       DADXDL010000284         1036 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.295, whole genome shotgun sequence.
ACCESSION   DADXDL010000284 DADXDL010000000
VERSION     DADXDL010000284.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1036)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1036)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1036
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.295"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1..1036
                     /locus_tag="IRB70_005038"
                     /pseudo
     CDS             1..1036
                     /locus_tag="IRB70_005038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558238.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
     misc_feature    165..281
                     /locus_tag="IRB70_005038"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /pseudo
                     /db_xref="RFAM:RF01497"
BASE COUNT          246 a          251 c          321 g          218 t
ORIGIN      
        1 attggctgta cgccggagac tctgcgtgtc tgggttcgcc agcatgagcg ggataccggg
       61 ggcggtgatg gagggctcac caccgctgaa cgtcagcgtc tgaaagagct ggaacgtgaa
      121 aatcgtgaac tgcgccgcag taacgatatc cttcgccagg cttccgctta ttttgcgaag
      181 gcggagttcg accgcctctg gaaaaagtga tgccactgct ggataagctg cgtaagctgt
      241 acggggtcgg accggtatgc agtgaactac atattgcccc gtcaacgtat taccactgtc
      301 agcaacagcg acatcatccg gataaacgca gtgcccgtgc gcagcgcgat gactggctga
      361 agaaagagat acagcgcgta tacgatgaaa atcacaaggt atacggtgtg cgtaaagtct
      421 ggcgtcagtt gttacgggaa ggtatcagag tggccagatg cactgtggca cgtctcatgg
      481 cggttatggg acttgccggt gttctccggg gtaaaaaggt ccgtacgacc atcagccgga
      541 aagccgttgc cgcaggcgac cgcgtaaacc gtcagttcgt ggcagaacga cctgaccagc
      601 tgtgggtggc tgattttact tacgtcagca catggcgggg cttcgtctat gtggcgttca
      661 tcattgatgt gtttgccgga tacatcgtgg ggtggcgggt ctcatcgtcc atggaaacga
      721 cattcgtgct ggatgcactg gagcaggcgt tatgggcccg tcgaccgtcc ggcacggtcc
      781 atcacagtga taaaggttct cagtatgtat cgctggccta cacacagcgg cttaaggaag
      841 ccggattact ggcatcaaca ggaagtacag gcgactcgta tgacaacgcg atggcggaga
      901 gcatcaatgg tctttacaaa gcggaggtaa tacaccgtaa gagctggaaa aaccgtgcag
      961 aagtggaact ggccacactc acgtgggtgg actggtataa caatcgacga ttgctggaaa
     1021 ggctgggcca tactcc
//
LOCUS       DADXDL010000285         1025 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.296, whole genome shotgun sequence.
ACCESSION   DADXDL010000285 DADXDL010000000
VERSION     DADXDL010000285.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1025)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1025)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1025
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.296"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>1025
                     /locus_tag="IRB70_005039"
     rRNA            <1..>1025
                     /locus_tag="IRB70_005039"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          244 a          233 c          322 g          226 t
ORIGIN      
        1 cgaagatacc agctggctgc aactgtttat taaaaacaca gcactgtgca aacacgaaag
       61 tggacgtata cggtgtgacg cctgcccggt gccggaaggt taattgatgg ggttagcggt
      121 aacgcgaagc tcttgatcga agccccggta aacggcggcc gtaactataa cggtcctaag
      181 gtagcgaaat tccttgtcgg gtaagttccg acctgcacga atggcgtaat gatggccagg
      241 ctgtctccac ccgagactca gtgaaattga actcgctgtg aagatgcagt gtacccgcgg
      301 caagacggaa agaccccgtg aacctttact atagcttgac actgaacatt gagccttgat
      361 gtgtaggata ggtgggaggc tttgaagtgt ggacgccagt ctgcatggag ccggccttga
      421 aataccaccc tttaatgttt gatgttctaa cgttggcccc tgatcggggt tgcggacagt
      481 gtctggtggg tagtttgact ggggcggtct cctcctaaag agtaacggag gagcacgaag
      541 gttggctaat cctggtcgga catcaggagg ttagtgcaat ggcataagcc agcttgactg
      601 cgagcgtgac ggcgcgagca ggtgcgaaag caggtcatag tgatccggtg gttctgaatg
      661 gaagggccat cgctcaacgg ataaaaggta ctccggggat aacaggctga taccgcccaa
      721 gagttcatat cgacggcggt gtttggcacc tcgatgtcgg ctcatcacat cctggggctg
      781 aagtaggtcc caagggtatg gctgttcgcc atttaaagtg gtacgcgagc tgggtttaga
      841 acgtcgtgag acagttcggt ccctatctgc cgtgggcgct ggagaactga ggggggctgc
      901 tcctagtacg agaggaccgg agtggacgca tcactggtgt tcgggttgtc atgccaatgg
      961 cactgcccgg tagctaaatg cggaagagat aagtgctgaa agcatctaag cacgaaactt
     1021 gcccc
//
LOCUS       DADXDL010000286         1019 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.297, whole genome shotgun sequence.
ACCESSION   DADXDL010000286 DADXDL010000000
VERSION     DADXDL010000286.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1019
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.297"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            61..495
                     /locus_tag="IRB70_005040"
     CDS             61..495
                     /locus_tag="IRB70_005040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001556209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-ribbon domain-containing protein"
                     /protein_id="HBC0634813.1"
                     /translation="MRILNCYMANDSKGHFVTAKEAAKHNRQDVLCCVSCGCPLTLQR
                     GNDGQPPWFEHDQMTVAEKILLRCTWLDPAEKEARRLHLQGMTVPDYTVKVRKWFCVM
                     CDEDYEGEKCCPRCGTGVYSRAWGRQEVPSEDARADNPLLRL"
     gene            829..>1019
                     /locus_tag="IRB70_005041"
     CDS             829..>1019
                     /locus_tag="IRB70_005041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010904653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634814.1"
                     /translation="MGTKVSDMQKNVNPGRRKGCPNYPPEFKQQLVAASCEPGISISK
                     LALENGINANLLFKWRQQWR"
BASE COUNT          252 a          230 c          292 g          245 t
ORIGIN      
        1 gtactgcaca cactgccaga ccggaggatt cagtattccc cggacaactc aggaggaaat
       61 atgcgaattc tgaactgtta tatggcgaat gacagcaaag gccattttgt tacggcgaaa
      121 gaagctgcga agcacaaccg acaggacgtt ttgtgctgtg tgtcctgtgg atgcccgtta
      181 acacttcagc ggggcaatga cggacaacca ccgtggtttg aacatgacca gatgactgtc
      241 gctgaaaaaa tcctgctgcg atgtacctgg cttgacccgg cagagaaaga ggcccgtcgt
      301 ttgcatctgc agggcatgac ggttccggat tatacggtga aggtgagaaa gtggttttgt
      361 gtgatgtgtg acgaagatta tgagggggaa aagtgctgcc cacgctgcgg taccggggta
      421 tacagcaggg cgtgggggcg gcaggaggtg ccgtcggaag atgccagggc tgataatccg
      481 ttactgaggc tgtaatggtt gcctccggag cagtttgcgg taatgccttt cccgggaatg
      541 gattgccagt gcggggactg tggagcttaa ttccggtgtt ggtggccttt ccgttgattt
      601 tatgccaaca gccccctgtg actgacaggc tgcctcgtca ttccattcgt atctccagta
      661 acagggggtt gtattgtatt ttattgtgcc ggttcagatg tgcgtttccc ggctcgtctg
      721 caccggctta accaaattca acagggataa aatagtggta agcgtacagc ctgaaccgtc
      781 tggtcagaat ctgacgaatt agacaaagtg gtgtccacca aataagtagt gggaaccaaa
      841 gtgtcagata tgcagaaaaa tgtgaatccc ggcaggcgaa aaggctgccc taattatcct
      901 cccgaattta aacagcagct cgttgctgcc tcctgtgaac ccgggatatc catctcaaaa
      961 cttgctcttg aaaatggcat taacgccaat ctgttgttca aatggcgaca acaatggcg
//
LOCUS       DADXDL010000287         1004 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.298, whole genome shotgun sequence.
ACCESSION   DADXDL010000287 DADXDL010000000
VERSION     DADXDL010000287.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1004)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1004)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1004
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.298"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>1004
                     /gene="ag43"
                     /locus_tag="IRB70_005042"
     CDS             <1..>1004
                     /gene="ag43"
                     /locus_tag="IRB70_005042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_026164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autotransporter adhesin Ag43"
                     /protein_id="HBC0634815.1"
                     /translation="NQKGRLQVDAGGTATNVTLKQGGALVTSTAATVTGINRLGAFSV
                     VEGKADNVVLENGGRLDVLTGHTATNTRVDDGGTLDVRNGGTATTVSMGNGGVLLADS
                     GAAVSGTRSDGKAFSIGGGQADALMLEKGSSFTLNAGDTATDTTVNGGLFTARGGTLA
                     GTTTLNNGAILTLSGKTVNNDTLTIREGDALLQGGSLTGNGSVEKSGSGTLTVSNTTL
                     TQKAVNLNEGTLTLNDSTVTTDVIAQRGTALKLTGSTVLNGAIDPTNVTLASGATWNI
                     PDNATVQSVVDDLSHAGQIHFTSTRTGKFVPATLKVKNLNGQNGTISLRVRPDMAQNN
                     A"
BASE COUNT          247 a          296 c          293 g          168 t
ORIGIN      
        1 aatcagaagg gcagactgca ggtggacgcc ggtggtacag ccacgaatgt caccctgaag
       61 cagggcggcg cactggttac cagtacggct gcaaccgtta ccggcataaa ccgcctggga
      121 gcattctctg ttgtggaggg taaagctgat aatgtcgtac tggaaaatgg cggacgcctg
      181 gatgtgctga ccggacacac agccactaat acccgcgtgg atgatggcgg aacgctggat
      241 gtccgcaacg gtggcaccgc caccaccgta tccatgggaa atggcggtgt actgctggcc
      301 gattccggtg ccgctgtcag tggtacccgg agcgacggaa aggcattcag tatcggaggc
      361 ggtcaggcgg atgccctgat gctggaaaaa ggcagttcat tcacgctgaa cgccggtgat
      421 acggccacgg ataccacggt aaatggcgga ctgttcaccg ccaggggcgg cacactggcg
      481 ggcaccacca cgctgaataa cggcgccata cttacccttt ccgggaagac ggtgaacaac
      541 gataccctga ccatccgtga aggcgatgca ctcctgcagg gaggctctct caccggtaac
      601 ggcagcgtgg aaaaatcagg aagtggcaca ctcactgtca gcaacaccac actcacccag
      661 aaagccgtca acctgaatga aggcacgctg acgctgaacg acagtaccgt caccacggat
      721 gtcattgctc agcgcggtac agccctgaag ctgaccggca gcactgtgct gaacggtgcc
      781 attgacccca cgaatgtcac tctcgcctcc ggtgccacct ggaatatccc cgataacgcc
      841 acggtgcagt cggtggtgga tgacctcagc catgccggac agattcattt cacctccacc
      901 cgcacaggga agttcgtacc ggcaaccctg aaagtgaaaa acctgaacgg acagaatggc
      961 accatcagcc tgcgtgtacg cccggatatg gcacagaaca atgc
//
LOCUS       DADXDL010000288          999 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.299, whole genome shotgun sequence.
ACCESSION   DADXDL010000288 DADXDL010000000
VERSION     DADXDL010000288.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 999)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 999)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..999
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.299"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..101
                     /locus_tag="IRB70_005043"
     CDS             <1..101
                     /locus_tag="IRB70_005043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="malate transporter"
                     /protein_id="HBC0634816.1"
                     /translation="ESNGHRVSLPLSVFNPQDYHPLLITVSGKNVN"
     gene            complement(214..>999)
                     /locus_tag="IRB70_005044"
     CDS             complement(214..>999)
                     /locus_tag="IRB70_005044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBC0634817.1"
                     /translation="PVQEPGSGKTRTARLWVYVRDDRNAGSQMPPAVWFAYSPDRKGI
                     HPQNHLAGYSGVLQADAYGGYRALYESGRITEAACMAHARRKIHDVHARAPTYITTEA
                     LQRIGELYAIEAEVRGCSAEQRLAARKARAAPLMQSLYDWIQQQMKTLSRHSDTAKAF
                     AYLLKQWDALNVYCSNGWVEIDNNIAENALRGVAVGRKNWMFAGSDSGGEHAAVLYSL
                     IGTCRLNNVEPEKWLRYVIEHIQDWPANRVRDLLPWKVDLSSQ"
BASE COUNT          203 a          292 c          253 g          251 t
ORIGIN      
        1 aagaaagtaa cggccatcgt gtcagtctgc cgttatcggt tttcaatccc caggactacc
       61 atccactgct gattaccgtt tccggaaaaa acgttaactg atccctgaag tcagtttcat
      121 gcttcagcct ctgtcacaac gcgtggcaga ggctttttat ttatcaggag aaaacagata
      181 tgcgtaagcg actcgtcaga accgtattga tatttactga gagctcagat caactttcca
      241 gggcaacaga tcgcgtaccc ggtttgccgg ccagtcctgg atatgttcaa tgacgtaacg
      301 cagccacttt tctggctcca cattgttcag acggcatgtg ccgatcagcg agtacaacac
      361 cgccgcatgt tcaccaccgc tgtcggaacc cgcgaacatc cagtttttcc ggcctacggc
      421 cactccccgt aaggcgttct ctgcgatgtt gttgtcgatt tccacccagc cattactgca
      481 gtacacgttc agtgcatccc actgtttcag caggtatgcg aacgcttttg ccgtatctga
      541 gtgacgcgac agtgttttca tctgttgctg tatccagtca tacagtgact gcatcagtgg
      601 cgcggctctg gcttttcttg ccgccagacg ctgttctgct gaacagcccc ggacctctgc
      661 ctcgatggca tacagttcac cgatacgctg cagggcttcc gtggtgatgt aggtgggcgc
      721 tcttgcatgc acatcgtgga tttttctccg ggcatgagcc atacacgcgg cttccgttat
      781 tctgccggat tcgtataacg cccggtaacc accgtaagca tcggcctgaa gcacaccgct
      841 gtaaccggcc aggtgatttt gtggatggat acctttccgg tccggactgt acgcgaacca
      901 gaccgccggg ggcatctgtg aaccggcgtt acggtcatca cggacgtaga cccacagccg
      961 ggctgtccgg gttttaccgc tgcccggctc ctggaccgg
//
LOCUS       DADXDL010000289          997 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.300, whole genome shotgun sequence.
ACCESSION   DADXDL010000289 DADXDL010000000
VERSION     DADXDL010000289.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 997)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 997)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..997
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.300"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            17..208
                     /locus_tag="IRB70_005045"
     CDS             17..208
                     /locus_tag="IRB70_005045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1482 family protein"
                     /protein_id="HBC0634818.1"
                     /translation="MNTAFALVLTVFLVSGEPVDIAVSVHRTMQECVTAATEQKIPGN
                     CYPVDKVIHQDNNEIPAGL"
     gene            301..>997
                     /locus_tag="IRB70_005046"
     CDS             301..>997
                     /locus_tag="IRB70_005046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBC0634819.1"
                     /translation="MSKVFICAAIPDEQAIKEEGAVAVATAIEAGDERRARAKFHWQF
                     LEHYPAAQDCAYKFLVCEDKPGIPRPALDSWDAEYMQENRWDEASASFVPVETESDPM
                     NVTFDNLAPEVQNAVMVKFDTCENITVDMVISAQELLQEDMATFDGHIVEALMKMPEV
                     NAMYPELKLHAIGWVKHKCKPGAKWPEIQAEMRIWKKRREGERKEAGKYTSVVDLARA
                     RANQQHTENSTGKI"
BASE COUNT          289 a          226 c          243 g          239 t
ORIGIN      
        1 aaaaaggatg ctggcaatga atacagcatt tgcacttgtt ctgacagttt ttcttgtttc
       61 cggagagcca gttgatattg cagtcagtgt tcacaggaca atgcaggagt gtgtgactgc
      121 agcaaccgaa cagaaaattc ccggtaactg ttacccggtc gataaagtta ttcaccagga
      181 taataacgaa atcccggcag gtctttaaaa cagttccgta ataaatatcc ggtttcattc
      241 ttatatgcca gcaatggcag ggatttgttc acccttaaat ctgtaatgag gtaaaacaaa
      301 atgagtaaag tctttatttg cgccgccatt ccggacgaac aggcaataaa ggaagaaggt
      361 gccgtcgctg tagccactgc cattgaagcc ggtgatgaac gtcgcgcccg cgcaaaattt
      421 cactggcaat tcctggaaca ttatccggct gctcaggact gcgcttataa atttcttgtt
      481 tgcgaggata aacccggtat accccgccct gccctcgatt cctgggatgc tgaatatatg
      541 caggaaaacc gctgggatga ggcgtctgct tcctttgtcc cggtcgagac tgaatccgat
      601 ccgatgaacg tcacttttga caacctagcc cctgaagtac agaacgctgt catggttaag
      661 ttcgacacat gtgaaaacat cactgttgat atggtgatta gcgcacagga attgttgcag
      721 gaagacatgg caacattcga cggccatatc gttgaagcgt tgatgaaaat gccagaagtt
      781 aacgctatgt atccggagct taagctgcat gccatcgggt gggttaagca taaatgtaag
      841 cctggtgcca aatggcccga aattcaggca gagatgcgca tctggaaaaa acgtcgcgaa
      901 ggtgaacgca aggaagccgg aaaatacacg tctgttgttg atctcgcccg cgccagagcc
      961 aatcaacagc acactgaaaa ttcaacagga aaaatca
//
LOCUS       DADXDL010000290          984 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.301, whole genome shotgun sequence.
ACCESSION   DADXDL010000290 DADXDL010000000
VERSION     DADXDL010000290.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..984
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.301"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..872)
                     /locus_tag="IRB70_005047"
     CDS             complement(<1..872)
                     /locus_tag="IRB70_005047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_417258.4"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YgcG family protein"
                     /protein_id="HBC0634820.1"
                     /translation="MRYFILIFTFVCSFVAAQPTIVPQLQQQVTDLTSSLNSQEKKEL
                     TRKLESIFNNTQVQIAVLIIPTTKDETIEQYATRVFNNWRLGDAKRNDGILIIVAWSD
                     RTVRIQVGYGLEEKVTDALAGDIIRSNMIPAFKQQKLAKGLELAIIALNNQLTSQHQY
                     SANPSESESASSSDYYYFAIFWVFAVMFFPFWFFHQGSNFCRACKSSVCISAIYLLDL
                     FLFSDKTFSIAVFFFFFTFTTIMVFTCLCVLQKKASGRSYHSDNSGSGGGSSGGGFSG
                     GGGSSGGGGASGRW"
     gene            complement(886..>984)
                     /locus_tag="IRB70_005048"
     CDS             complement(886..>984)
                     /locus_tag="IRB70_005048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_002791252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634821.1"
                     /translation="TFTEIILIFSVFVFNYNESQITGAAVNLFIQL"
BASE COUNT          319 a          193 c          203 g          269 t
ORIGIN      
        1 taccagcgac cggacgcgcc gccaccgcca gaagaaccgc ccccgccgct aaatccgccg
       61 ccacttgagc cgccaccgga accgctgttg tctgaatgat aacttctacc agatgctttt
      121 ttctgaagta cacataaaca ggtaaagacc ataatggtgg tgaaagtaaa aaagaagaaa
      181 aatacagcaa tggaaaaagt tttatcggag aacaggaata aatctaaaag atagattgct
      241 gaaatacaga cactgctttt acatgcgcga caaaaattac tgccttgatg aaaaaaccag
      301 aaagggaaga acatcactgc aaatacccaa aaaatagcaa agtagtaata atcgctggaa
      361 gacgctgatt cactttctga aggattagcc gaatattggt gttgtgaagt gagttggtta
      421 ttcaaagcga ttatagctaa ctctaatccc ttagctaatt tttgttgttt aaatgcgggt
      481 atcatgttgc tacggatgat atctccagcc agagcatcgg ttaccttttc ttccagccca
      541 taacctacct ggatgcggac agtgcgatcc gaccaggcaa caatgatcag tatcccatca
      601 ttgcgtttgg catctcctaa acgccaattg ttaaaaaccc ttgtagcata ttgttcaatt
      661 gtctcgtctt tggttgtggg aataattaat acagcaattt gtacttgggt attattgaaa
      721 atagattcta acttccgcgt cagttctttc ttttcttgtg agtttaagct actcgtaaga
      781 tccgtaactt gttgctgtaa ttgtgggaca atagttggtt gggctgcaac aaaggaacac
      841 acgaatgtga atattagtat gaaatagcgc attataaatg tcccattaaa gctggataaa
      901 taaattgacg gcggcaccgg taatttgaga ttcgttataa ttaaaaacga acacagaaaa
      961 aataagtata atttcggtga atgt
//
LOCUS       DADXDL010000291          975 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.302, whole genome shotgun sequence.
ACCESSION   DADXDL010000291 DADXDL010000000
VERSION     DADXDL010000291.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 975)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 975)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..975
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.302"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1..975
                     /locus_tag="IRB70_005049"
                     /pseudo
     CDS             1..975
                     /locus_tag="IRB70_005049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558238.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
     misc_feature    113..229
                     /locus_tag="IRB70_005049"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /pseudo
                     /db_xref="RFAM:RF01497"
BASE COUNT          235 a          228 c          305 g          207 t
ORIGIN      
        1 ataccggggg cggtgatggt gggctcacca gcgctgaacg tcagcgtctg aaagagctgg
       61 aacgtgaaaa tcgtgaactg cgccgcagta acgatatcct tcgccaggct tccgcttatt
      121 ttgcgaaggc ggagttcgac cgcctctgga aaaaatgatg ccactgctgg ataagctgcg
      181 tgagcagtac ggggtcggac cggtatgcag cgaactgcat attgccccgt caacgtatta
      241 ccattgtcag caacagcgac atcatccgga taaacgcagt gcccgtgcgc agcacgacga
      301 ctggctgaag agagagatac agcgcgtata cgatgaaaat catcaggtgt acggtgtgcg
      361 taaagtctgg cgtcagttgt tacgggaagg aatcagggtg gccagatgta cagtggcacg
      421 tctcatggcg gttatgggac ttgccggtgt tctccggggt aaaaaggtcc gtacgaccat
      481 cagccggaaa gccgttgccg caggcgaccg cgtaaaccgt cagttcgtgg cagaacgacc
      541 tgaccagctg tgggtggctg attttactta cgtcagcaca tggcagggct tcgtctatgt
      601 ggcgtttatc attgatgtgt ttgccggata catcgtgggg tggcgggtct catcgtctat
      661 ggaaacgaca ttcgtgctgg atgtgctgga gcaggcgttg tgggcccgtc gtccgtctgg
      721 caccatccat cacagcgata aaggctctca gtatgtgtca ctggcctata cggagcgact
      781 aaaagaagcc ggattactgg catcaacagg gagtacaggc gactcgtatg acaacgcgat
      841 ggctgagagc atcaatggtc tttacaaagc ggaggtaata caccgtaaga gctggaaaaa
      901 ccgtgcagaa gtggaactgg ccacactaac gtgggtggac tggtataaca atcgacgatt
      961 gctgggaagg ctggg
//
LOCUS       DADXDL010000292          957 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.303, whole genome shotgun sequence.
ACCESSION   DADXDL010000292 DADXDL010000000
VERSION     DADXDL010000292.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 957)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 957)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..957
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.303"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(154..825)
                     /gene="queE"
                     /locus_tag="IRB70_005050"
     CDS             complement(154..825)
                     /gene="queE"
                     /locus_tag="IRB70_005050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001199960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="7-carboxy-7-deazaguanine synthase QueE"
                     /protein_id="HBC0634822.1"
                     /translation="MQYPINEMFQTLQGEGYFTGVPAIFIRLQGCPVGCAWCDTKHTW
                     EKLEDREVSLFSILAKTKESDKWGAASSEDLLAVIGRQGYTARHVVITGGEPCIHDLL
                     PLTDLLEKNGFSCQIETSGTHEVRCTPNTWVTVSPKLNMRGGYEVLSQALERANEIKH
                     PVGRVRDIEALDELLATLTDDKPRVIALQPISQKDDATRLCIETCIARNWRLSMQTHK
                     YLNIA"
BASE COUNT          265 a          227 c          213 g          252 t
ORIGIN      
        1 tccagcgaaa aattaacgcc acagaatttg tagagaatga taatgattag ttcaggatgg
       61 gcaagatgga tgagttttca gaggcgacaa acaatataaa tgagtagaag tctttacagg
      121 ttccacccat ttataacgct tataaatgtt taatcaggca atatttagat atttatgtgt
      181 ttgcatcgac aaacgccaat tacgcgcaat gcaggtttca atgcacaaac gtgtggcatc
      241 atccttttgg ctaatcggct gcagtgcaat gactcgcggt ttatcatcgg tcagcgttgc
      301 cagtagttca tccagtgctt caatatcacg tacgcgcccc actggatgct tgatttcgtt
      361 ggctcgctcc agtgcctgtg acaacacttc atagccgccg cgcatgttca actttggtga
      421 tacggtaacc caggtattcg gtgtgcagcg tacctcatga gtaccactgg tttcgatctg
      481 gcagctaaaa ccgttctttt cgagcagatc agtcagtggc agcaaatcat gaatgcaagg
      541 ctcaccaccc gtaatcacca catgccgtgc ggtgtatccc tggcgaccaa tgacagccag
      601 caaatcttca ctgctcgcag ccccccactt atcactctct ttggtcttcg ccagaatgct
      661 gaaaagggag acttcccgat cctcaagctt ttcccaggtg tgtttggtgt cgcaccaggc
      721 acagccaacc gggcatccct gtaaacgaat aaaaatggcg gggacgccgg taaagtaacc
      781 ctcaccttgc agggtctgga acatctcgtt aatcgggtac tgcatagcat tctctgtgaa
      841 gtggataatt gttaattatt gcagatcctg ccacaacaat catgtcttat taacattctg
      901 ttacaggcag gtttaaagaa aaatgagaaa cagatcgtta ataataaaag gaagtaa
//
LOCUS       DADXDL010000293          953 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.304, whole genome shotgun sequence.
ACCESSION   DADXDL010000293 DADXDL010000000
VERSION     DADXDL010000293.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 953)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 953)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..953
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.304"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..944)
                     /locus_tag="IRB70_005051"
     CDS             complement(<1..944)
                     /locus_tag="IRB70_005051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein/permease"
                     /protein_id="HBC0634823.1"
                     /translation="MITIPITFCMLIAKYLCLLKPFWLRKNNKTSVLLIIIILAMILG
                     VVKIQVWLNDWNNDFFNALSQKETDKLWQLVLWFPALLGIFVLISVNKTWLIKLLTIR
                     WREWLTDYYLNRWFADKNYYFTQIYGEHKNTDNPDQRIAEDILLLISKTLSLSFGFIQ
                     SLSMLITFTVILWQSAGTLSFTVGGTEWNIQGYMVYTVVLIVIGGTLFTHKVGKRIRP
                     LNVEKQRSEATFRTNLVQHNKQAELIALSNAESLQRQELSENFHTIKENWHRLMNRQR
                     WLDYWQNIYSRSLSVLPYFLLLPQFISGQINLGGLMKSR"
BASE COUNT          292 a          201 c          201 g          259 t
ORIGIN      
        1 cgcgatttca tcagtccgcc cagattgatc tgtccgctaa taaactgcgg caataacaga
       61 aagtagggaa gaacgctaag cgagcgcgaa taaatattct gccagtaatc aagccaccgc
      121 tgacgattca ttaaacgatg ccagttctct ttaatggtat gaaaattttc gctcaactcc
      181 tggcgttgta gagactcagc attgcttagc gcaatcagtt ctgcctgctt attatgctgc
      241 acaagattag ttcgaaatgt cgcttcgcta cgttgttttt ccacattaag cggacgaata
      301 cgtttaccaa ccttatgggt aaataaagtt ccaccgatca caatgagcac gacggtatag
      361 accatatacc cctggatatt ccattcagtt ccaccaacag tgaatgagag cgtacccgcg
      421 ctttgccaaa gaataacggt aaaggtgatc agcatgctaa gtgactggat gaagccaaat
      481 gaaagactga gcgttttgct gatcagtaag agaatgtctt cagcgatacg ttggtcaggg
      541 ttatctgtat ttttatgctc gccgtagatc tgcgtgaagt agtagttttt atctgcaaac
      601 cagcgattaa ggtagtaatc tgttaaccat tcgcgccagc gaatagtcag tagtttaatt
      661 aaccatgttt tgtttacgga tattaataca aagatcccca gcagggcagg gaaccaaagg
      721 acaagctgcc aaagcttatc agtttctttc tggcttagcg cattgaaaaa atcattattc
      781 cagtcgttta accagacctg aattttaacc acgccaagga tcatggcgag gataataatg
      841 attaacaaca ctgaagtttt attattctta cgcagccaaa agggcttcag cagacagaga
      901 tactttgcta tcaacataca aaacgtaatg ggaatggtta tcattagcga aaa
//
LOCUS       DADXDL010000294          939 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.305, whole genome shotgun sequence.
ACCESSION   DADXDL010000294 DADXDL010000000
VERSION     DADXDL010000294.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 939)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 939)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..939
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.305"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>939
                     /locus_tag="IRB70_005052"
     CDS             <1..>939
                     /locus_tag="IRB70_005052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III effector"
                     /protein_id="HBC0634824.1"
                     /translation="CSFKNVIFSGVINSPNLEGPVFENCYFEDCKFNNIQLYETNDDT
                     VGSGNKKPIKGMFKGCFISKCKIENYRCETSKIYTVTQPDSIQEKLGSYLFMQSFVQD
                     CIIQGGRCPGSSILLSHFYNCTIAKLDAHGMDFLANAFNKSGDNETRAQDQGTVFDCC
                     NLNSIKMNCGLGNVSSDEYKFNPEEYFSDYIERRSRNLKLDDNFSNCVENIEKAVTTS
                     FSKENSENDNISFNCCDLRRANLDNYYRDDLCKDCSIDPDSIYLEDGVTPIKYIYMNL
                     DGAISKDQIPNFLKKVSAINSDVKDFYNTELKIKEEY"
BASE COUNT          322 a          116 c          191 g          310 t
ORIGIN      
        1 tgtagtttta aaaatgtaat tttttcagga gtgataaaca gccctaacct tgaaggtccg
       61 gtttttgaaa attgttattt cgaggattgt aaattcaaca acatacagct ttatgagact
      121 aatgatgata ctgtggggtc aggaaataaa aaaccaataa aaggtatgtt taaaggttgt
      181 tttatttcta aatgcaaaat tgaaaattat agatgtgaga cgtctaaaat ctacaccgtt
      241 acacaacctg atagtattca agaaaaatta ggttcttatc tctttatgca gtctttcgtt
      301 caggattgta taattcaggg aggacgttgt cctggttcga gtatacttct gagtcatttt
      361 tataactgta cgatagcgaa acttgatgct catgggatgg attttttggc aaacgcattc
      421 aataagtctg gtgataacga aaccagggcg caggatcagg gaactgtgtt tgattgttgt
      481 aatttgaata gtattaaaat gaactgtggt cttggtaatg tgagttcaga tgaatataag
      541 tttaaccccg aagagtattt ttctgattac attgaaagaa gatcgagaaa tcttaagttg
      601 gatgataatt tttctaactg cgtagagaat atcgagaagg ctgttacaac ttcatttagc
      661 aaggaaaatt cagagaatga taatatctcc tttaattgtt gtgatttgag gagggccaat
      721 ttagacaatt attacagaga tgatttgtgc aaagactgtt ctattgatcc agattcaatt
      781 tatttagaag atggtgttac accgataaaa tatatttata tgaatctgga cggagctata
      841 agtaaagacc aaatacctaa tttcttaaaa aaggtaagtg ctatcaatag cgatgtaaaa
      901 gatttttata atactgagct aaagattaag gaagaatat
//
LOCUS       DADXDL010000295          916 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.306, whole genome shotgun sequence.
ACCESSION   DADXDL010000295 DADXDL010000000
VERSION     DADXDL010000295.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 916)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 916)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..916
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.306"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>916
                     /locus_tag="IRB70_005053"
     CDS             <1..>916
                     /locus_tag="IRB70_005053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4-like element IS4 family transposase"
                     /protein_id="HBC0634825.1"
                     /translation="HWCGLTLLAIDGVFWRTPDTPENDAAFPRQTHAGNPALYPQVKM
                     VCQMELTSHLLTAAAFGTMKNSENELAEQLIEQTGDNTLTLMDKGYYSLGLLNAWSLA
                     GEHRHWMIPLRKGAQYEEIRKLGKGDHLVKLKTSPQARKKWPGLGNEVTARLLTVTRK
                     GKVCHLLTSMTDAMRFPGGEMADLYSHRWEIELGYREIKQTMQLSRLTLRSKKPELVE
                     QELRGVLLAYNLVRYQMIKMAEHLKGYWPNQLSFSESCGMVMRMLMTLQGASPGRIPE
                     LMRDLASMGQLVKLPTRRERAFPRVVKER"
BASE COUNT          262 a          213 c          273 g          168 t
ORIGIN      
        1 cactggtgcg gcctgaccct gctggccatc gatggtgtgt tctggcgcac accggataca
       61 ccagagaacg atgcagcctt cccccgccag acacatgccg ggaacccggc gctctacccg
      121 caggtcaaaa tggtctgcca gatggaactg accagccatc tgctgacggc tgcagccttc
      181 ggcacgatga agaacagcga aaatgagctt gctgagcaac ttatagaaca aaccggcgat
      241 aacactctga cgttaatgga taaaggttat tactcactgg gactgttaaa tgcctggagc
      301 ctggcgggag aacaccgcca ctggatgata cctctcagaa agggagcgca atatgaagag
      361 atcagaaaac tgggtaaagg cgatcatctg gtgaagctga aaaccagccc gcaggcacga
      421 aaaaagtggc cgggactggg aaatgaagtg acagcccgcc tgctgaccgt gacgcgcaaa
      481 ggaaaagtct gccatctgct gacgtcgatg acggacgcca tgcgcttccc cggaggagaa
      541 atggcggatc tgtacagtca tcgctgggaa atcgaactgg gatacaggga gataaaacag
      601 acgatgcaac tgagcaggct gacgctgaga agtaaaaaac cggagcttgt ggagcaagag
      661 ctgcggggtg tcttactggc ttataatctg gtgagatatc agatgattaa aatggcggaa
      721 catctgaaag gttactggcc gaatcaactg agtttctcag aatcatgcgg aatggtgatg
      781 agaatgctga tgacattgca gggcgcttca ccgggacgta taccggagct gatgcgcgat
      841 cttgcaagta tgggacaact tgtgaaatta ccgacaagaa gggaaagggc cttcccgaga
      901 gtggtaaagg agaggc
//
LOCUS       DADXDL010000296          885 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.308, whole genome shotgun sequence.
ACCESSION   DADXDL010000296 DADXDL010000000
VERSION     DADXDL010000296.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 885)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 885)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..885
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.308"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..441
                     /locus_tag="IRB70_005054"
     CDS             <1..441
                     /locus_tag="IRB70_005054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="colanic acid biosynthesis glycosyltransferase
                     WcaI"
                     /protein_id="HBC0634826.1"
                     /translation="IVGEGAGKKRLEEKVLSSQLTNVLFRPLQPYNKLPLLLSMADCH
                     LVIQKRGAADAVLPSKLTNILAVGGNAIITAEIHTELGQLTTNYPGIAVRVEPESDVS
                     LTEGLIHALSLPKFNSIAESYANKMLDKEVILNEYLEVISSKVN"
     gene            480..>885
                     /locus_tag="IRB70_005055"
     CDS             480..>885
                     /locus_tag="IRB70_005055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001775097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634827.1"
                     /translation="MNRRKFISFLSFSALYSSSRLSWGSDLYHINSMSELRNFKPEYI
                     GQEVYLESYYVGVGRGGGYFTFHEGVCNDNGGTVISAVGGGYWLRSLHNDLCLVYDFG
                     ARDDIDGFDSTNAIQGAIDNCNHISLGGGHFNI"
BASE COUNT          269 a          133 c          190 g          293 t
ORIGIN      
        1 atcgtgggtg aaggtgctgg taaaaaacgt ctcgaagaaa aagtactcag cagtcaatta
       61 acaaatgtat tatttcgtcc cttacagcct tataataaat taccgctatt gctaagtatg
      121 gctgattgcc acttagttat tcagaaaaga ggcgcagctg atgcggtgtt accttcaaaa
      181 cttacaaaca tccttgctgt tggtggtaac gctattatta cagctgaaat tcatacagaa
      241 ctaggtcagt taacaactaa ctatcctggt attgcagtac gagttgaacc agagagtgat
      301 gtttcactta cggaaggatt aattcatgca ttatcacttc ctaaattcaa tagtatagct
      361 gaatcttatg ctaataaaat gcttgataaa gaagtgatcc taaatgaata ccttgaggta
      421 atatctagta aggttaacta attttatatt atgatatgaa tcatcttttg aggaatcata
      481 tgaatcgaag aaaatttatt tcttttttgt ctttttcggc attgtattct tcttctcgat
      541 tgagttgggg aagtgattta tatcatataa actctatgtc tgaattacgt aattttaaac
      601 cggagtatat cgggcaggag gtttatctcg agtcctacta cgttggagtt ggcagaggag
      661 gaggctattt tacattccac gaaggtgttt gtaatgataa tggtggtaca gttataagcg
      721 cagttggagg aggctactgg cttcgaagtt tacataacga tctttgtttg gtttacgatt
      781 ttggtgcacg agatgacata gatggttttg atagcacaaa tgctattcag ggagcgatag
      841 ataattgtaa tcatataagc ttgggagggg gccatttcaa tatat
//
LOCUS       DADXDL010000297          877 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.309, whole genome shotgun sequence.
ACCESSION   DADXDL010000297 DADXDL010000000
VERSION     DADXDL010000297.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 877)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 877)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..877
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.309"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..468
                     /locus_tag="IRB70_005056"
     CDS             <1..468
                     /locus_tag="IRB70_005056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF932 domain-containing protein"
                     /protein_id="HBC0634828.1"
                     /translation="YFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFDR
                     IEEKRDAMQSLVLPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWSA
                     YQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETMLESLR"
     gene            550..>877
                     /locus_tag="IRB70_005057"
     CDS             550..>877
                     /locus_tag="IRB70_005057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBC0634829.1"
                     /translation="MKTVSQNTPTIYSATTPENNPPQLVASLVPDEQRISFWPQHFGL
                     IPQWVTLEPRVFGWMDRLCEDYCGGIWNLYTLNNGGAFMAPEPDDDDDETWVLFSAMN
                     GNRAEMS"
BASE COUNT          206 a          227 c          251 g          193 t
ORIGIN      
        1 tacttcaggt tcgtctgcca gaacggctgc gtctgtggtc agtctctggg ggaagtacgt
       61 gttccgcacc ggggaaatgt ggtggacaga gtcattgaag gggcttacga ggtggtgggc
      121 gtgtttgacc ggatagagga gaagcgtgat gccatgcagt cgctggtcct gccgccaccg
      181 gcacgccagg cgctggcaca ggcggcactg acttaccgtt atggtgacga acatcagccc
      241 gtcaccaccg ccgacattct gacgccgcga cgccgggagg attacggtaa ggacctgtgg
      301 agcgcatatc agaccatcca ggagaatatg ctgaaaggcg ggatttccgg tcgcagtgca
      361 aaaggaaaac gtatccatac ccgggccatt cacagcattg ataccgacat taagctcaat
      421 cgcgcattgt gggtgatggc agaaacgatg ctggagagcc tgcgctgatg ccgtttccct
      481 gagtgaggga atcattcagc tttcgttcct gaaaaacaca catttatttg ttatttaagg
      541 agttatctca tgaaaaccgt ttctcagaat acccccacaa tttattcagc tacaacacca
      601 gagaataatc cgcctcagtt ggttgccagc ctcgtccctg atgaacagcg catcagcttc
      661 tggccgcagc attttggcct cattccacag tgggtgaccc tggagccccg tgtcttcggc
      721 tggatggacc gtctgtgcga agactactgc ggtggtatct ggaatctgta caccctgaac
      781 aacggcgggg catttatggc acccgaaccg gatgacgatg atgacgaaac atgggtactg
      841 ttcagtgcca tgaacggtaa ccgcgcagaa atgagcc
//
LOCUS       DADXDL010000298          873 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.310, whole genome shotgun sequence.
ACCESSION   DADXDL010000298 DADXDL010000000
VERSION     DADXDL010000298.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..873
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.310"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            294..>873
                     /locus_tag="IRB70_005058"
     CDS             294..>873
                     /locus_tag="IRB70_005058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634830.1"
                     /translation="MSPDNISSAVNRFSGWPSNDPLKTDKESMTSPMTVQVIKMIAAI
                     LDPYRIVVGIDTLYTTQRETFTSESQQLIESALQTLHVINLNNLETNLDEDGHYLAFG
                     YNVDTPDRITVSAYNEKKPDCYGQCLLIQDDETDLFNLIKVKIFEARHNYVAQLMSDP
                     EFMFKFSYSAQQNRLEPHLLVPTYFPLKTNEPV"
BASE COUNT          275 a          172 c          158 g          268 t
ORIGIN      
        1 accaattgat tagattagcc aatttgttgc tattttacat aacatatttt tatcaaagtt
       61 aattgattgt tgcctttatg agcaccggcc gtaagcccgt tatgttattg tttcattagt
      121 aataatcact taaatgtatc gatgaaacag gtatgactta gcgggagtga ttgtttctga
      181 gtgaacagag accactttcg cctgataaat gaaaaatgag cgatttttgc aagttagttt
      241 ttctatagcc gagtacgctc agcgcctcgc ttgattacaa tgaggttgct gctatgagtc
      301 ctgataatat cagttctgct gtcaatcgct tctcaggttg gccatctaat gatcctctaa
      361 aaacagataa agaatcaatg acatcaccca tgactgtgca ggtaataaag atgattgccg
      421 ccatccttga cccatatcgg atagtcgttg gaatcgatac actttataca acgcagcgcg
      481 aaacatttac ctcagagagt caacagctca ttgaatcagc attgcaaaca cttcatgtga
      541 taaatttaaa taacctggaa acaaatctcg atgaggacgg tcactatctg gcttttggat
      601 ataacgttga cactcctgac agaataaccg tttctgctta taatgaaaaa aagcctgact
      661 gctatggcca atgtctttta atacaggatg acgaaacaga cttatttaac ctgataaaag
      721 ttaaaatttt tgaagccagg cataattatg tcgctcaatt gatgagcgat cccgaattta
      781 tgttcaaatt tagttatagc gctcaacaaa atagattaga acctcatctt ctggttccca
      841 cttatttccc tctaaaaaca aacgaaccgg tta
//
LOCUS       DADXDL010000299          871 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.311, whole genome shotgun sequence.
ACCESSION   DADXDL010000299 DADXDL010000000
VERSION     DADXDL010000299.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 871)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 871)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..871
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.311"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>871
                     /locus_tag="IRB70_005059"
     rRNA            <1..>871
                     /locus_tag="IRB70_005059"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          222 a          196 c          285 g          168 t
ORIGIN      
        1 gagtaatgtc tgggaaactg cctgatggag ggggataact actggaaacg gtagctaata
       61 ccgcataacg tcgcaagacc aaagaggggg accttcgggc ctcttgccat cggatgtgcc
      121 cagatgggat tagctagtag gtggggtaaa ggctcaccta ggcgacgatc cctagctggt
      181 ctgagaggat gaccagccac actggaactg agacacggtc cagactccta cgggaggcag
      241 cagtggggaa tattgcacaa tgggcgcaag cctgatgcag ccatgccgcg tgtatgaaga
      301 aggccttcgg gttgtaaagt actttcagcg gggaggaagg gagtaaagtt aatacctttg
      361 ctcattgacg ttacccgcag aagaagcacc ggctaactcc gtgccagcag ccgcggtaat
      421 acggagggtg caagcgttaa tcggaattac tgggcgtaaa gcgcacgcag gcggtttgtt
      481 aagtcagatg tgaaatcccc gggctcaacc tgggaactgc atctgatact ggcaagcttg
      541 agtctcgtag aggggggtag aattccaggt gtagcggtga aatgcgtaga gatctggagg
      601 aataccggtg gcgaaggcgg ccccctggac gaagactgac gctcaggtgc gaaagcgtgg
      661 ggagcaaaca ggattagata ccctggtagt ccacgccgta aacgatgtcg acttggaggt
      721 tgtgcccttg aggcgtggct tccggagcta acgcgttaag tcgaccgcct ggggagtacg
      781 gccgcaaggt taaaactcaa atgaattgac gggggcccgc acaagcggtg gagcatgtgg
      841 tttaattcga tgcaacgcga agaaccttac c
//
LOCUS       DADXDL010000300          850 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.312, whole genome shotgun sequence.
ACCESSION   DADXDL010000300 DADXDL010000000
VERSION     DADXDL010000300.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 850)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 850)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..850
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.312"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>850
                     /locus_tag="IRB70_005060"
     rRNA            <1..>850
                     /locus_tag="IRB70_005060"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          239 a          184 c          260 g          167 t
ORIGIN      
        1 gtacacaaaa atgcacatac tgtgagctcg atgagtaggg cgggacacgt ggtatcctgt
       61 ctgaatatgg ggggaccatc ctccaaggct aaatactcct gactgaccga tagtgaacca
      121 gtaccgtgag ggaaaggcga aaagaacccc ggcgagggga gtgaaaaaga acctgaaacc
      181 gtgtacgtac aagcagtggg agcctcttaa tggggtgact gcgtaccttt tgtataatgg
      241 gtcagcgact tatattctgt agcaaggtta accgaatagg ggagccgaag ggaaaccgag
      301 tcttaactgg gcgttaagtt gcagggtata gacccgaaac ccggtgatct agccatgggc
      361 aggttgaagg ttgggtaaca ctaactggag gaccgaaccg actaatgttg aaaaattagc
      421 ggatgacttg tggctggggg tgaaaggcca atcaaaccgg gagatagctg gttctccccg
      481 aaagctattt aggtagcgcc tcgtgaattc atctccgggg gtagagcact gtttcggcaa
      541 gggggtcatc ccgacttacc aacccgatgc aaactgcgaa taccggagaa tgttatcacg
      601 ggagacacac ggcgggtgct aacgtccgtc gtgaagaggg aaacaaccca gaccgccagc
      661 taaggtccca aagtcatggt taagtgggaa acgatgtggg aaggcccaga cagccaggat
      721 gttggcttag aagcagccat catttaaaga aagcgtaata gctcactggt cgagtcggcc
      781 tgcgcggaag atgtaacggg gctaaaccat gcaccgaagc tgcggcagcg acactatgtg
      841 ttgttgggta
//
LOCUS       DADXDL010000301          848 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.313, whole genome shotgun sequence.
ACCESSION   DADXDL010000301 DADXDL010000000
VERSION     DADXDL010000301.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..848
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.313"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(386..544)
                     /locus_tag="IRB70_005061"
     CDS             complement(386..544)
                     /locus_tag="IRB70_005061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_052660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Hok family toxin"
                     /protein_id="HBC0634831.1"
                     /translation="MKLPRSSLVWCVLIVCLTLLIFTYLTRKSLCEIRYRDGHREVAA
                     FMAYESGK"
     gene            complement(742..>848)
                     /locus_tag="IRB70_005062"
     CDS             complement(742..>848)
                     /locus_tag="IRB70_005062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBC0634832.1"
                     /translation="VTEYIEYYNSRRISLKLKGLTPIEYRNQTYMPRV"
BASE COUNT          232 a          219 c          221 g          176 t
ORIGIN      
        1 cgccagcagc tgcctgtcgg agtcgggcct gacgaccgga tgccgccagg cagccgggag
       61 ccgaaggtgc gcccggcaga caggacaaca ctgcagtagt cagaatcaga gcaggaagaa
      121 aaagagaata atcacaggga aggtgatgtg atttctgaca ggccataacc agagaaggcg
      181 ggggaaaaga acgggcgccg caggcgcgcg ttcatccccg ttcctgaagg gaaacgacct
      241 tcctgaagtc aggttgttca tgcccgtaca acatcagcaa ggagaaaggg gctaccggcg
      301 aaccagcagc ccctttataa aggcgcttca gtagtcagac cagcatcagt cctgaaaagg
      361 cgggcctgcg cccgcctcca ggttgctact taccggattc gtaagccatg aaagccgcca
      421 cctccctgtg tccgtctctg taacgaatct cgcacagcga ttttcgtgtc agataagtga
      481 atatcaacag tgtgagacac acgatcaaca cacaccagac aagggaactt cgtggtagtt
      541 tcatggcctt cttctccttg cgcaaagcgc ggtaagaggc tatcctgatg tggactagac
      601 atagggatgc ctcgtggtgg ttaatgaaaa ttaacttact acggggctat cttctttctg
      661 ccacacaaca cggcaacaaa ccaccttcac gtcatgaggc agaaagcctc aagcgtgtac
      721 tgaccccaaa aagttggaca gttaaacacg aggcatatag gtctgattcc gatattcaat
      781 tggagtcaga ccttttaatt tcaggctaat tcttctgctg ttgtagtatt caatatattc
      841 cgtaacag
//
LOCUS       DADXDL010000302          832 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.314, whole genome shotgun sequence.
ACCESSION   DADXDL010000302 DADXDL010000000
VERSION     DADXDL010000302.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 832)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 832)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..832
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.314"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..750
                     /gene="yeeO"
                     /locus_tag="IRB70_005063"
     CDS             <1..750
                     /gene="yeeO"
                     /locus_tag="IRB70_005063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416491.3"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic metabolite efflux MATE transporter YeeO"
                     /protein_id="HBC0634833.1"
                     /translation="IGFNPALRISLKSYFKPLNFSIIWEVMGIGIPASVESVLFTSGR
                     LLTQMFVAGMGTSVIAGNFIAFSIAALINLPGSALGSASTIITGRRLGVGQIAQAEIQ
                     LRHVFWLSTLGLTAIAWLTAPFAGVMASFYTQDPQVKHVVVILIWLNALFMPIWSASW
                     VLPAGFKGARDARYAMWVSMLSMWGCRVVVGYVLGIMLGWGVVGVWMGMFADWAVRAV
                     LFYWRMVTGRWLWKYPRPEPQKCEKKPVVSE"
BASE COUNT          176 a          161 c          237 g          258 t
ORIGIN      
        1 attggtttta atcctgcgct aaggatttcg ttaaagagct attttaaacc gctgaatttt
       61 agcattatct gggaagtcat ggggattggt attcccgcga gtgtcgaatc agtgttattt
      121 accagtggtc ggttattaac ccaaatgttc gttgccggga tggggaccag tgttattgcc
      181 ggaaatttta tcgcgttttc aattgcggct cttatcaact tacccggaag tgcgctcggc
      241 tctgcttcta cgatcattac aggccgaagg ttgggtgtag gacagatagc gcaagcagag
      301 attcagttgc ggcatgtgtt ctggctttcc actcttggat taacggccat cgcctggcta
      361 acggctccct ttgccggggt tatggcatcg ttttacaccc aggatccaca ggttaaacat
      421 gtcgttgtga ttctgatttg gctaaatgct ttatttatgc ctatttggtc tgcctcatgg
      481 gtgctacccg ctggatttaa gggtgctcgc gatgcacgtt acgccatgtg ggtttctatg
      541 ttgagcatgt ggggttgccg ggttgtagtc ggttatgtgc tgggaatcat gcttggctgg
      601 ggtgtggttg gtgtctggat gggaatgttt gccgactggg ctgtgcgggc cgtgctgttt
      661 tactggcgaa tggttactgg acgttggctg tggaaatatc ctcgacctga gccgcaaaag
      721 tgtgagaaaa agccagttgt gtcggaataa acgacaaagt gcagattatt tcagcaaacg
      781 atttcaaatt taaaaaacag gctttgacat tgtggatgag cgtcgctaat at
//
LOCUS       DADXDL010000303          824 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.315, whole genome shotgun sequence.
ACCESSION   DADXDL010000303 DADXDL010000000
VERSION     DADXDL010000303.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 824)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 824)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..824
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.315"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>824)
                     /locus_tag="IRB70_005064"
     CDS             complement(<1..>824)
                     /locus_tag="IRB70_005064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="FHIPEP family type III secretion protein"
                     /protein_id="HBC0634834.1"
                     /translation="LIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVIREGEGLN
                     DEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDA
                     QKLTKIGCYTRTAMDEMYNHLSVCLAHNINEYFGIQETKYILDQLEMKYPDLLKEILR
                     YITVQRISEVIQRLIQERISVRNMRLVMEVLALWSPREKDIITLVEHVRGALGRYICH
                     KFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGIN"
BASE COUNT          262 a          176 c          126 g          260 t
ORIGIN      
        1 attgattcca gaaagagcca gtttaaaatt atccagaatc atctcagctt cggatgcatc
       61 gagattaaga aaagtaccgc cagcggtagg cctgacacca tctctgattc tgtcctctat
      121 ttcaggcgaa atcacaattg ctttaatttc tccagaatat gaaaacttat ggcaaatgta
      181 gcgacctaat gcacctcgta catgctcgac gagtgtaatt atatctttct ctcgtgggct
      241 ccataatgct aaaacctcca taactaaacg catattgcgc actgaaattc gctcctggat
      301 cagacgctga attacctctg aaatgcgctg cacggttata tatcttaata tttcttttaa
      361 tagatcagga tacttcatct ctaattgatc aagaatatat ttagtttctt gtataccaaa
      421 atactcatta atattatgcg ccagacatac agataaatga ttgtacattt catccatggc
      481 cgtgcgagta taacagccaa tttttgttaa tttttgggca tcactttttg taacccaata
      541 atattgttca ccattactat ttacgatgac aggtttcttg atcaaagtcg aaaccacttc
      601 atctgaatat tcaaccaaca agacgagatc atgataaatt ttaaattgcg aggctctgac
      661 ttcatttagc attaatatga catcttcatc attaaggcct tccccctcgc gaatgacaat
      721 accgggaata cggataccat attcaataaa aaactgacta cgaatcctat cagcaagatt
      781 gatttcagtg tattttttag cctgtacact attcataatc aaaa
//
LOCUS       DADXDL010000304          808 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.316, whole genome shotgun sequence.
ACCESSION   DADXDL010000304 DADXDL010000000
VERSION     DADXDL010000304.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..808
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.316"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            27..284
                     /gene="pemI"
                     /locus_tag="IRB70_005065"
     CDS             27..284
                     /gene="pemI"
                     /locus_tag="IRB70_005065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system antitoxin PemI"
                     /protein_id="HBC0634835.1"
                     /translation="MHTTRLKRVGGSVMLTVPPALLNALSLGTDNEVGMVIDNGRLIV
                     EPYRRPQYSLAELLAQCDPNAEISAEEREWLDAPATGQEEI"
     gene            217..618
                     /gene="pemK"
                     /locus_tag="IRB70_005066"
     CDS             217..618
                     /gene="pemK"
                     /locus_tag="IRB70_005066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001398199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system toxin
                     endoribonuclease PemK"
                     /protein_id="HBC0634836.1"
                     /translation="MLKYQLKNENGWMHRRLVRRKSDMERGEIWLVSLDPTAGHEQQG
                     TRPVLIVTPAAFNRVTRLPVVVPVTSGGNFARTAGFAVSLDGVGIRTTGVVRCDQPRT
                     IDMKARGGKRLERVPETIMNEVLGRLSTILT"
BASE COUNT          186 a          185 c          231 g          206 t
ORIGIN      
        1 aaatataact tttatggagg tgaagaatgc ataccacccg actgaagagg gttggcggct
       61 cagttatgct gaccgtccca ccggcactgc tgaatgcgct gtctctgggc acagataatg
      121 aagttggcat ggtcattgat aatggccggc tgattgttga gccgtacaga cgcccgcaat
      181 attcactggc tgagctactg gcacagtgtg atccgaatgc tgaaatatca gctgaagaac
      241 gagaatggct ggatgcaccg gcgactggtc aggaggaaat ctgacatgga aagaggggaa
      301 atctggcttg tctcgcttga tcctaccgca ggtcatgagc agcagggaac gcggccggtg
      361 ctgattgtca caccggcggc ctttaatcgc gtgacccgcc tgcctgttgt tgtgcccgta
      421 accagcggag gcaattttgc ccgcactgcc ggctttgcgg tgtcgttgga tggtgttggc
      481 atacgtacca caggtgttgt acgttgcgat caaccccgga caattgatat gaaagcacgg
      541 ggcggaaaac gactcgaacg ggttccggag actatcatga acgaagttct tggccgcctg
      601 tccactattc tgacttgaac atggggtttg aggggcaact ggatgaaaac gtacgattta
      661 gggcactaaa accgctgttg tcccaccatt ctggtgattc ccaaacgtta tttggctaaa
      721 aagtagtttt gatgtggttt attttccgaa ttccaagcgc agccctactt tcttgtgcgt
      781 atttgcgtgt tttgcgcagt tttgaagt
//
LOCUS       DADXDL010000305          806 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.317, whole genome shotgun sequence.
ACCESSION   DADXDL010000305 DADXDL010000000
VERSION     DADXDL010000305.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 806)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 806)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..806
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.317"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(105..326)
                     /locus_tag="IRB70_005067"
     CDS             complement(105..326)
                     /locus_tag="IRB70_005067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_708771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF987 domain-containing protein"
                     /protein_id="HBC0634837.1"
                     /translation="MKIITRGEAMRIHRQHPASRLFPFCTGKYRWHGSTEAYTGREVQ
                     DIPGVLAVFAERHKDSFGPYVRLMSVTLN"
     gene            complement(389..>806)
                     /locus_tag="IRB70_005068"
     CDS             complement(389..>806)
                     /locus_tag="IRB70_005068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="RadC family protein"
                     /protein_id="HBC0634838.1"
                     /translation="RALKTLDRHLHEPGVAFTSTRAAREWLILNMAGLEREEFRVLYL
                     NNQNQLIAGETLFTGTINRTEVHPREVIKRALYHNAAAVVLAHNHPSGEVTPSKADRL
                     ITERLVQALGLVDIRVPDHLIVGGNQVFSFAEHGLL"
BASE COUNT          181 a          202 c          245 g          178 t
ORIGIN      
        1 gcacagaccg gcttcggtga aggtgtattc gttgatgagt agggcctcat ccacagcggc
       61 gtctgagctc agccagtcgt actcgttttc cgggtgacgg aacatcagtt cagggtgacg
      121 ctcatcagcc ggacatacgg gccaaaactg tccttatggc gttcagcaaa cacggccagc
      181 acaccgggaa tatcctgcac ttcacgaccg gtatacgctt cagtgctgcc gtgccagcgg
      241 tatttgccgg tacagaaagg aaaaagacgg gatgccggat gctgacggtg aatacgcatg
      301 gcttcgccac gggtgatgat tttcatagtg tgatacctct gaagacagaa gataaaagtg
      361 aaaacaggtg tgatgtggtt gtgaagggtt aaagcagacc atgttcggca aaggagaaaa
      421 cctggttgcc accgactatc agatggtccg gcacccggat atccaccagg cccagtgcct
      481 gtaccagacg ttccgtgata aggcggtctg ccttactggg tgtgacttca ccggaggggt
      541 gattgtgtgc cagcaccacg gcagcggcat tgtggtacag ggcgcgttta atcacttccc
      601 ggggatggac ttccgtgcgg ttgatggtgc cggtaaagag ggtttcaccg gcaatcagtt
      661 gattctggtt attcagatac agcacccgga attcttcacg ctccagtccc gccatgttca
      721 gaatcagcca ttcccgtgct gcacgggtgg aggtgaaggc cacgccgggt tcatgaagat
      781 ggcggtccag ggttttcagg gcccgt
//
LOCUS       DADXDL010000306          795 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.318, whole genome shotgun sequence.
ACCESSION   DADXDL010000306 DADXDL010000000
VERSION     DADXDL010000306.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 795)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 795)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..795
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.318"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            22..738
                     /locus_tag="IRB70_005069"
     CDS             22..738
                     /locus_tag="IRB70_005069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBC0634839.1"
                     /translation="MGRKWANIVAKKTAKDGATSKIYAKFGVEIYAAAKQGEPDPELN
                     TSLKFVIERAKQAQVPKHVIDKAIDKAKGGGDETFVQGRYEGFGPNGSMIIAETLTSN
                     VNRTIANVRTIFNKKGGNIGAAGSVSYMFDNTGVIVFKGSDPDHIFEILLEAEVDVRD
                     VTEEEGNIVIYTEPTDLHKGIAALKAAGITEFSTTELEMIAQSEVELSPEDLEIFEGL
                     VDALEDDDDVQKVYHNVANL"
BASE COUNT          261 a          140 c          166 g          228 t
ORIGIN      
        1 attttcgagg agatcattcc agtgggacgt aaatgggcca atattgttgc taaaaaaacg
       61 gctaaagacg gtgcaacgtc taaaatttat gcaaaattcg gtgtagaaat ctatgctgct
      121 gctaaacaag gtgaacccga tccagaatta aacacatctt taaaattcgt tattgaacgt
      181 gcaaaacagg cacaagttcc aaagcacgtt attgataaag caattgataa agccaaaggc
      241 ggcggagatg aaacattcgt gcagggccgt tatgaaggct ttggtcctaa tggctcaatg
      301 attatcgccg agacattgac ttcaaatgtt aaccgtacga ttgctaacgt tcgcacaatt
      361 ttcaataaaa aaggcggcaa tatcggagcg gcaggttctg tcagctatat gtttgacaat
      421 actggtgtga ttgtatttaa aggatcagac cctgaccata tttttgaaat tttacttgaa
      481 gctgaagttg atgttcgtga tgtgactgaa gaagaaggta acattgttat ttataccgaa
      541 cctactgacc ttcataaagg aatcgctgct ctaaaagcag ctggaatcac ggagttctca
      601 acaacagaat tagaaatgat tgctcaatca gaagttgagc tttccccaga agatttagaa
      661 atctttgaag ggcttgttga tgcccttgaa gatgacgacg atgtacaaaa agtttatcat
      721 aacgtcgcaa atctctaatt atattttaaa gaaatctgtc tttatggcag atttctttaa
      781 tctcatagaa tcctt
//
LOCUS       DADXDL010000307          777 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.319, whole genome shotgun sequence.
ACCESSION   DADXDL010000307 DADXDL010000000
VERSION     DADXDL010000307.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 777)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 777)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..777
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.319"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>777)
                     /locus_tag="IRB70_005070"
     CDS             complement(<1..>777)
                     /locus_tag="IRB70_005070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Ig-like domain-containing protein"
                     /protein_id="HBC0634840.1"
                     /translation="VTSQTAGTSAVTASINSSSLSRNVTFVADVRTAKIASLEVTQDN
                     SVADGAMANTLRVKVTDAFGNALNGQTVSVMADNGATVAPTVITEPDGTVEISVTSQT
                     AGTSTVTASINNSSQSRNVTFIADVRTAQIADLVVIKDGSEADGATANTLRARVTDAF
                     GNALAGQTVSVLADNGATTAPTVITEPDGTVEISVTSQTAGISAVTATINNSTASQNV
                     MFIADVRTTKIADLVVIKDDSVADGAMANTLQVKVTDANGN"
BASE COUNT          118 a          262 c          210 g          187 t
ORIGIN      
        1 attcccgtta gcatcggtga ccttcacttg cagcgtgttc gccattgcac cgtctgccac
       61 tgagtcgtcc ttaatgacca ccaggtccgc gatcttcgtc gtcctgacat cggcgataaa
      121 catcacattc tgactcgcgg tgctgttgtt gatggttgca gtgaccgcac tgattccggc
      181 ggtctggctg gtgacagaga tctccaccgt accgtcgggc tctgtgatga ccgtcggggc
      241 agtcgttgcg ccgttgtccg ccaacacgct gaccgtctgc ccggcaagcg cattaccgaa
      301 tgcatcggtc accctcgccc gtagcgtgtt cgccgtcgca ccgtccgcct ctgaaccgtc
      361 cttaatgacc accagatccg cgatctgcgc cgtcctgaca tcggcgataa acgtcacgtt
      421 ccggctctgg ctgctgttgt tgatactggc agtgactgta ctggttcccg ccgtctggct
      481 ggtgacactg atttccaccg tgccgtccgg ctcggtgatc accgtcgggg caaccgttgc
      541 gccgttgtcc gccatcacgc tgaccgtctg tccattcagc gcattcccga acgcatcggt
      601 gaccttcacc cgcagcgtgt tcgccattgc gccgtcagcc actgagttat cctgcgtcac
      661 ctccagactc gcgatcttcg ccgtcctgac atcggcaaca aacgtcacgt tccggctcag
      721 gctgctgctg ttgatgctgg cagtgaccgc actggtgcct gccgtctggc tggtgac
//
LOCUS       DADXDL010000308          776 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.320, whole genome shotgun sequence.
ACCESSION   DADXDL010000308 DADXDL010000000
VERSION     DADXDL010000308.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..776
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.320"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..742
                     /locus_tag="IRB70_005071"
     CDS             <1..742
                     /locus_tag="IRB70_005071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020802722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="type III restriction endonuclease subunit R"
                     /protein_id="HBC0634841.1"
                     /translation="SIPALLSKGLKEKGKYDKKDMYINTTSTSFDKNSIFYLIDQLKN
                     HSNSNATLPQLGPFHPYIPNCDLVLCTDMDTEPCDFIVSSPDKLCFIHVKCGKSFSSP
                     KSSAGAIAEVGSQAIKNLTYLISHSDANTPGNYSIWDKAWPSHKAKHKLESRFRLAFN
                     EIGKIPNKENKLKEKTWELISNRRKSPLCNKEIWIVMGNSFSKKHFIEEMSKDTDQQS
                     ETIQAFQLIEDWLSSADEMGVDIKIFTS"
BASE COUNT          292 a          141 c          124 g          219 t
ORIGIN      
        1 aagcattcca gccctgcttt caaagggtct taaagaaaaa ggaaagtatg ataaaaaaga
       61 tatgtatatt aatactacaa gtacaagctt tgataagaat tctatatttt atttaattga
      121 tcaattaaaa aaccactcaa atagcaatgc tactcttcca caattgggcc cctttcatcc
      181 ttatattcca aattgcgatc tcgttctttg cactgacatg gatacagaac catgtgattt
      241 tatcgtatca tcaccggata aattatgttt cattcatgta aaatgtggga aatcattcag
      301 ttctccaaaa tcctcagcag gagcgatagc agaagtcgga agtcaagcaa ttaaaaactt
      361 aacctatctg atttcacact cagatgctaa taccccagga aactattcta tttgggataa
      421 agcatggcca tcccataaag ccaaacataa acttgagtct cgttttagat tagcctttaa
      481 cgaaattgga aagatcccta ataaagaaaa taaacttaag gaaaaaacct gggagttaat
      541 atctaataga agaaaatcac cactgtgcaa taaagaaata tggatagtaa tgggcaactc
      601 tttttcgaaa aaacatttca ttgaagagat gtcaaaagat actgaccagc aatctgaaac
      661 aatacaagct tttcaactaa tcgaagattg gttaagtagt gctgatgaga tgggtgtaga
      721 tataaaaata ttcacatcat aacaaactca cttccccgac acatttaagt gtgtcg
//
LOCUS       DADXDL010000309          774 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.321, whole genome shotgun sequence.
ACCESSION   DADXDL010000309 DADXDL010000000
VERSION     DADXDL010000309.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 774)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 774)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..774
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.321"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>774)
                     /locus_tag="IRB70_005072"
     CDS             complement(<1..>774)
                     /locus_tag="IRB70_005072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FHIPEP family type III secretion protein"
                     /protein_id="HBC0634842.1"
                     /translation="MLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSI
                     LLITTLFRLALAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIV
                     ITKGSERVAEVAARFSLDGMPGKQMSIDADLRAGIIDADLAKERRSVLERESQLYGSF
                     DGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLVSQIP
                     ALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIIVT"
BASE COUNT          270 a          174 c          137 g          193 t
ORIGIN      
        1 tgtcacaata atgacaaaag aattacttaa taactgggac attatatttt gccccatatt
       61 atcactatcg ccattcacgc gcgttacgat aaaccctgcg ctaatagcaa ttaataaagc
      121 tggaatttga gaaacaagac catcaccgac ggtaagaatt gtgtagacgg tcaacgctgt
      181 cgagaaatcc attccatttt ggcctactcc tactgatagc ccaccgataa tattaacaaa
      241 gataataata atgtttgcaa tagcatcacc tttgataaat ttcatcgcac catcaaagga
      301 accatacagc tgactctctc gttctaatac gctacgacgt tcttttgcta aatctgcatc
      361 aatgatcccg gcgcgtagat cggcgtcaat actcatttgt ttacctggca taccgtcaag
      421 cgaaaagcgg gcagcaactt cagccacacg ttccgaacct ttagtaatca cgataaactg
      481 aacaatagtc acaatggaga aaataacaaa accaactacc aggctatcgc caataacgaa
      541 ttcaccaaaa ctcgttataa tttctccggc gtccgcctca agaagtataa gtcggctggt
      601 actgatcgcc agcgccaaac gaaataacgt tgtgatgaga agaattgatg ggaatgaaga
      661 aaaacttaag atcctatcaa catagaatga tcctaaaaat acaagtattg ccaatgttaa
      721 gttcagccca atcaaaaaat cgattaagta ggtgggcaat ggaattatga gcat
//
LOCUS       DADXDL010000310          749 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.322, whole genome shotgun sequence.
ACCESSION   DADXDL010000310 DADXDL010000000
VERSION     DADXDL010000310.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..749
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.322"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..225)
                     /locus_tag="IRB70_005073"
     CDS             complement(<1..225)
                     /locus_tag="IRB70_005073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3289 family protein"
                     /protein_id="HBC0634843.1"
                     /translation="MNNILLPPINIPCTLFETINLFDDFSADDMQYGDMVEQDFLSLG
                     LSDISAKVDPYRLIKYHFPSPGSINVAFSAS"
     gene            382..558
                     /locus_tag="IRB70_005074"
     CDS             382..558
                     /locus_tag="IRB70_005074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001351582.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA"
                     /protein_id="HBC0634844.1"
                     /translation="MLNLPIRKLFPTRIASSDGMNFEFMPELKWSFGYPGAIIFMILA
                     GLAPYLYFKRKNWL"
BASE COUNT          239 a          137 c          151 g          222 t
ORIGIN      
        1 tgaggcacta aaagcaacat taatagaacc tgggctaggg aaatggtatt taataagtcg
       61 gtaaggatca acttttgctg agatatcgct taggccgagt gagagaaagt cttgttctac
      121 catatcacca tattgcatat catcagcaga aaaatcatcg aataaattaa tagtttcgaa
      181 aagtgtacag ggaatattaa ttggcggaag taatatgtta ttcatttgca tttgccttag
      241 ttatatttaa gctcaatatc aattcgagaa caaatgctag ggtaaaaaaa tatttaaaaa
      301 agaagtacac ttcacatttt ttcattacat ctctgaagag aacgtcgtta atgattggtc
      361 ttgctcattg ttaataacaa aatgttgaat ttaccgatta ggaaactttt tcctacgcgg
      421 attgcctcca gcgatggcat gaactttgag tttatgccgg aactgaagtg gagtttcggc
      481 taccctggcg cgattatctt tatgatcctc gcgggcctgg caccgtatct gtactttaag
      541 cggaagaact ggttgtaaaa aactagagcg gtggcttagc ctggctaagc cacctgttat
      601 tcaaaggctc caggtattta acccttttac ctctttctca taaaaccatt tgttcgtgtt
      661 aacagcaaca taggctgcta cggcaattcc cagaatgtta acgccaatta gtgcaccaac
      721 aaatagagat agaatgccaa gtaatagaa
//
LOCUS       DADXDL010000311          721 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.323, whole genome shotgun sequence.
ACCESSION   DADXDL010000311 DADXDL010000000
VERSION     DADXDL010000311.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 721)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 721)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..721
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.323"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(61..192)
                     /locus_tag="IRB70_005075"
     CDS             complement(61..192)
                     /locus_tag="IRB70_005075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014639590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3927 family protein"
                     /protein_id="HBC0634845.1"
                     /translation="MIAYCFCEWHCSSRIMSVLADGVLVAGVVVVAFPLLKKKTPDC"
BASE COUNT          238 a          184 c          120 g          179 t
ORIGIN      
        1 aacagtcaac cgcctgaatt gtgaagtatt taaaaatttc tcccgctaac tgatacccgg
       61 ctaacagtct ggcgttttct ttttcagcaa cgggaaagca acaaccacca cacccgccac
      121 cagcacaccg tcagccagca ctgacattat ccggctgctg caatgccatt cacaaaaaca
      181 gtaagcaatc actttttacc gtaacaggtg ataatccaga tatgtatcta ccccagatga
      241 gtaatccgaa gttcatccat accacaggtc ctggctattc tgttgtactc ctgaacaaga
      301 gcaaataatt ctgaattagc aaccatgaac tcatcgcaaa ccctctgtat agcatcacta
      361 ttcagaataa taacgtctct tcccgaaaga cgatcaggag cacagaacaa aactgtcaaa
      421 cggctgaagg cctttgctcg tgctgcattg actatatcaa tacgctgcct aaggatgaaa
      481 caccccgacg cctcatcaat attcactcta cccacaccat atgaatgata aatatttaat
      541 gctgaaaaaa ccattagacc gtataacaaa cactcaatca atacttaaca gaacttttat
      601 ttttgacaaa catattatgt tttcaacaat atcctgagcc aggtatattc cagtataagg
      661 ctctgccgga aggaatctgg aagaatgaat atggcgcgct gtactggatt cgaaccagtg
      721 a
//
LOCUS       DADXDL010000312          704 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.324, whole genome shotgun sequence.
ACCESSION   DADXDL010000312 DADXDL010000000
VERSION     DADXDL010000312.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 704)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 704)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..704
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.324"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            6..206
                     /locus_tag="IRB70_005076"
     CDS             6..206
                     /locus_tag="IRB70_005076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001398364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634846.1"
                     /translation="MNETLNKIDDEIATIDKEIVKLKDETERLEKEYEQENTLNDVVQ
                     NIRSWLKENQNMVKAIKKIDTE"
BASE COUNT          257 a          115 c          144 g          188 t
ORIGIN      
        1 gtaagattaa tgaaacacta aataaaatag atgacgaaat agcaacaata gataaagaga
       61 ttgtaaagct taaggatgaa acagagagat tggagaaaga gtatgaacaa gaaaatacac
      121 ttaatgatgt agttcaaaat atcaggagtt ggctaaaaga aaatcaaaat atggtgaaag
      181 ctattaagaa aattgatact gaataacatg gcgaataaat aaacggatca agtcgttcct
      241 gtgacaatga ggttatacaa aaagacgctt actcatcaga aatctggtat gctttaatta
      301 aaccagtgtc gctgatgtgt aagcgttgac gttgggaggc gattaaatgg ttataccact
      361 cctacgcctt ttccagacgg cgtataagag tgcaacatgt tgagttttcc gagtgaatgg
      421 tgcattttac taaccgagcc atttgaatca accaacgcaa taaaaaagac tggaataata
      481 agcctgtatt tattattcat cgcaaccgca ctctacggtt ttatcctgca gaaatgagac
      541 tacttccagc ggttgtggat tatccctggg cgatagtcat agtctggtgt caggattcac
      601 aaatgacctg ttacctgaca tggatataaa cacaacatag agtgcggtag ttaatctgaa
      661 tcatctattt ttcggctaca cagcacaaaa caacattatt gatt
//
LOCUS       DADXDL010000313          696 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.325, whole genome shotgun sequence.
ACCESSION   DADXDL010000313 DADXDL010000000
VERSION     DADXDL010000313.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 696)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 696)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..696
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.325"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>696
                     /locus_tag="IRB70_005077"
     CDS             <1..>696
                     /locus_tag="IRB70_005077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634847.1"
                     /translation="TCAISQTLEEQPVLNSKSWLTSLQNDYSLPDSLTERIWLTLISQ
                     RISRGELREFELADGNWLLNNAWYERNMAGFNEQLKENLSFTPDELKTLFRNRLNLSP
                     EANDDFLDRCLDGGDWYPFSEGRRFVSFHHVDELRICASCGLTEVHHAPENHKPDPEW
                     YCSSLCRETETLCQEIYERPYNSFISDATANGLILMKLPETWSTNEKMFASGGQGHGF
                     AAERGNHIVDRVRL"
BASE COUNT          185 a          168 c          178 g          165 t
ORIGIN      
        1 acctgtgcca tcagccagac actggaagaa caaccggtgc tcaacagtaa atcgtggctg
       61 accagtttgc aaaacgatta cagccttcct gactcactga cggagcgcat ctggctgacg
      121 ctcatttctc aacggatttc ccggggagag ctgagggaat ttgaactggc agacggaaac
      181 tggttactga acaatgcctg gtatgaaaga aacatggcag ggtttaacga acagttgaaa
      241 gagaacctgt cattcacacc tgatgaactg aaaacgctct tccggaaccg cctgaattta
      301 tcaccggaag cgaatgacga ttttctcgat cgttgcctgg acggcggtga ctggtatccc
      361 ttttcagaag gtcgccgttt tgtatcattc catcacgtgg atgagcttcg tatctgtgcc
      421 tcctgcgggc tgacagaagt acatcatgcc ccggaaaatc ataagccgga tccggaatgg
      481 tactgctcct ctctttgtcg cgaaacagaa acactgtgtc aggaaattta tgaacgccct
      541 tacaacagct ttatttccga tgcaacggcg aatggtctga ttctcatgaa actgccggaa
      601 acctggagta caaatgagaa aatgtttgct tccggagggc agggacatgg gtttgccgct
      661 gaacggggaa accatattgt cgacagagtc cgtctg
//
LOCUS       DADXDL010000314          687 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.326, whole genome shotgun sequence.
ACCESSION   DADXDL010000314 DADXDL010000000
VERSION     DADXDL010000314.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 687)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 687)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..687
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.326"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            137..>687
                     /gene="acrS"
                     /locus_tag="IRB70_005078"
     CDS             137..>687
                     /gene="acrS"
                     /locus_tag="IRB70_005078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux transporter transcriptional
                     repressor AcrS"
                     /protein_id="HBC0634848.1"
                     /translation="MAKRTKAEALKTRQELIETAIAQFAQHGVSKTTLNDIADAANVT
                     RGAIYWHFENKTQLFNEMWLQQPSLRELIQEHLTAGLEHDPFQQLREKLIVGLQYIAK
                     IPRQQALLKILYHKCEFNDEMLAEGVIREKMGFNPQTLHEVLQACQQQGCIANNLDLD
                     VVMIIIDGAFSGIVQNWLMNMAG"
BASE COUNT          208 a          136 c          152 g          191 t
ORIGIN      
        1 ataataaacg ttatttattt gacgatttat agcaactcaa tattagcctc tcgtataaat
       61 acacattagg tgatagatta accttcgcta ttttctcact ctgtgtcgaa tatatttatt
      121 tcctgaataa ttaatcatgg caaaaagaac caaagccgaa gctctgaaga cccggcaaga
      181 actgattgaa actgccatcg cccagtttgc gcaacatggc gtaagcaaga cgacgctcaa
      241 cgacattgcc gatgccgcta acgttacgcg tggcgctatc tactggcact tcgagaacaa
      301 gacccaactg tttaatgaga tgtggttgca acagccttca ttgcgggagt taatccagga
      361 acacttgacg gctgggttag agcatgaccc gtttcaacaa ttgcgtgaaa aattgattgt
      421 tggcttgcaa tatattgcca aaattccccg ccagcaggcg ttgctgaaaa tcttatatca
      481 caaatgtgaa tttaatgatg agatgctggc agagggagtg atacgcgaaa agatgggctt
      541 taatccgcag actctccacg aagtattgca ggcatgtcag caacaaggtt gtatagcaaa
      601 taatctcgat ttagatgttg tgatgattat tattgatggt gccttcagcg gaattgttca
      661 aaactggtta atgaatatgg cgggtta
//
LOCUS       DADXDL010000315          675 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.328, whole genome shotgun sequence.
ACCESSION   DADXDL010000315 DADXDL010000000
VERSION     DADXDL010000315.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 675)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 675)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..675
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.328"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            92..339
                     /locus_tag="IRB70_005079"
                     /pseudo
     CDS             92..339
                     /locus_tag="IRB70_005079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612254.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            442..>675
                     /locus_tag="IRB70_005080"
     CDS             442..>675
                     /locus_tag="IRB70_005080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000952428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBC0634849.1"
                     /translation="MLSREDFYMIKQMRQQGAYIVDIATQIGCSERTVRRYLKYPEPP
                     ARKTRHKMVKLKPFMDYIDMRLAENVWNSEVIFA"
BASE COUNT          189 a          176 c          160 g          150 t
ORIGIN      
        1 gcaaccagcg ccttcagccg gttgatttca gaagcataag ccgccacccg ctgtgtgtag
       61 tggcacagta agtttggcca cctgattaaa ggtgatattc tcacctcaac acaaaacagg
      121 tgacttaatg aacaagaaaa ccaaacgtac tttcaccccc gagttcagac tggaatgtgc
      181 gcaactgatt gttgataagg gctactcata tcgacaagcc agtgaatcga tgaatgtcgg
      241 ctctaccact cttgagagct gggtacgtca gctcagacga gagcgccagg ggattgcccc
      301 tctgccacac cgattactcc agaccagcaa cgtatccgcg tgtcagcgcc agtgatataa
      361 gacggtaatt caccatttgg attgtccgct ccacccaaca tgttgtttcc ttaaggttct
      421 cacaccagaa aggacatcaa catgctgagc agagaggact tttacatgat aaagcaaatg
      481 cgccagcagg gcgcgtacat tgtcgatatt gcgactcaga ttggttgctc tgaacggacg
      541 gtcagacgct acctcaaata ccctgaaccg ccagccagaa agacccgcca caaaatggtt
      601 aagctgaaac cgtttatgga ttacatcgac atgcgcctgg cagagaatgt ctggaatagt
      661 gaggttatct tcgcg
//
LOCUS       DADXDL010000316          658 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.329, whole genome shotgun sequence.
ACCESSION   DADXDL010000316 DADXDL010000000
VERSION     DADXDL010000316.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..658
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.329"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..495
                     /locus_tag="IRB70_005081"
     CDS             <1..495
                     /locus_tag="IRB70_005081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4329 domain-containing protein"
                     /protein_id="HBC0634850.1"
                     /translation="LYTYPLSPVNGMDPLGLYEFKSKNIDDIGIFALAMCNGESINEN
                     KEYGGLICKKQGEYFPMNPISSNDNDSVDLRNIKSPEGSERVGDYYTHGFYSDDKGNK
                     VTKENDVYDSLNFSSKDLTNSYMNGMEKKECSSYLGTPNNTYIKYNPEAKGNGVTIIR
                     QGSN"
     gene            497..>658
                     /locus_tag="IRB70_005082"
     CDS             497..>658
                     /locus_tag="IRB70_005082"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634851.1"
                     /translation="MKAIQCCYFLALVSSHLMAGVMSDDNIFLSNLDLAALYCVAKIF
                     PDGENILIYK"
BASE COUNT          251 a           77 c          132 g          198 t
ORIGIN      
        1 ctgtatacat atccgctgag cccggtgaat ggcatggatc cattaggatt atatgaattt
       61 aaatcaaaaa atatagatga cattggaata tttgcattgg caatgtgtaa tggagaatca
      121 attaacgaga ataaagaata tggtggacta atatgtaaga agcaaggtga atatttcccc
      181 atgaatccga taagttcaaa tgataatgat agtgtagact tgcgaaatat aaaaagccct
      241 gaaggttcag agagagtagg cgattattac actcacggtt tttactctga cgataaagga
      301 aataaagtaa caaaagaaaa tgatgtttat gatagtctaa atttttcaag caaagattta
      361 acgaattctt atatgaatgg aatggaaaaa aaagaatgca gtagttactt gggaacacca
      421 aataacacct atataaaata taatcccgaa gctaaaggga atggagttac aattatcagg
      481 caagggagta attaaaatga aggcaataca atgttgttat ttccttgctt tagtctccag
      541 tcatttaatg gctggggtta tgagtgatga caatatattt ttaagtaatt tggatttagc
      601 tgctttatat tgtgtggcta aaatatttcc agatggagaa aatattttaa tatataaa
//
LOCUS       DADXDL010000317          650 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.330, whole genome shotgun sequence.
ACCESSION   DADXDL010000317 DADXDL010000000
VERSION     DADXDL010000317.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.330"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..468
                     /locus_tag="IRB70_005083"
     CDS             <1..468
                     /locus_tag="IRB70_005083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF932 domain-containing protein"
                     /protein_id="HBC0634852.1"
                     /translation="YFRFVCQNGCVCGQSLGEVRVPHRGNVVDRVIEGAYEVVGVFDR
                     IEEKRDAMQSLILPPPARQALAQAALTYRYGDEHQPVTTADILTPRRREDYGKDLWSA
                     YQTIQENMLKGGISGRSAKGKRIHTRAIHSIDTDIKLNRALWVMAETLLESLR"
     gene            523..>650
                     /locus_tag="IRB70_005084"
     CDS             523..>650
                     /locus_tag="IRB70_005084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein"
                     /protein_id="HBC0634853.1"
                     /translation="MKTISHNSTTSSVSVTAASGNDQPQLVATLVPDEQRISFWPQ"
BASE COUNT          151 a          175 c          179 g          145 t
ORIGIN      
        1 tacttcaggt tcgtctgcca gaacggatgc gtctgtggtc agtctctggg ggaagtgcgt
       61 gttccgcacc ggggaaatgt ggtggacaga gtcattgaag gggcttacga ggtggtgggc
      121 gtgtttgacc ggattgagga aaagcgtgat gccatgcagt cgctgattct gccgccaccg
      181 gcacgccagg cgctggcaca ggcggcactg acttaccgtt atggtgacga acatcagccc
      241 gtcaccaccg ccgacattct gacgccacga cgccgggagg attacggtaa ggacctgtgg
      301 agtgcttatc agaccattca ggagaatatg ctgaaaggcg gaatttcagg tcgcagcgct
      361 aaaggaaaac gtatccatac ccgtgccatt cacagcattg acactgacat taagctcaac
      421 cgcgcattgt gggtgatggc ggaaaccctg ctggagagcc tgcgctgatt cagccattac
      481 cctgaaaacc acgcatttat ttgtccttta aggagtcatt tcatgaaaac catttcacat
      541 aattccacca catcttctgt ttccgtaacc gctgcatcag ggaatgacca gcctcagctg
      601 gttgccaccc tcgtccctga tgaacagcgc atcagcttct ggccgcagca
//
LOCUS       DADXDL010000318          640 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.331, whole genome shotgun sequence.
ACCESSION   DADXDL010000318 DADXDL010000000
VERSION     DADXDL010000318.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..640
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.331"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            84..>640
                     /locus_tag="IRB70_005085"
     CDS             84..>640
                     /locus_tag="IRB70_005085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001599750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634854.1"
                     /translation="MIRYSGIFLSLLMLSGCATEALKNEQAETVITAGNKAVAANASF
                     FKQYYASRENFLVNFYATNPDCALRPDYETIMENNTNKESLCLQSEKGGKTSYKDITK
                     IQLATTEKQKLLASLEVVNSMSSYVELLTVGMDVEDSKQIILLNQALDHANNAQKLLG
                     FSEGEELTKSAVAVKDLVQYFNGLY"
BASE COUNT          216 a          102 c          132 g          190 t
ORIGIN      
        1 catacttgct tatgaatatt accaggaaat agccacatta ctatttaatt atctgagata
       61 aactcaacgt caagaggtgg gttatgatta gatatagtgg aatatttcta tcgctgttaa
      121 tgctttcagg ttgtgcaacc gaagcattga agaatgaaca agctgaaact gttattactg
      181 cgggtaacaa ggcggttgcg gcgaatgcaa gtttctttaa acaatactat gcttctcgtg
      241 aaaacttcct tgttaatttt tatgcgacta atccggattg tgcattgcga cctgattatg
      301 aaacgattat ggaaaataat actaataaag agtccttatg tttgcaatca gagaaagggg
      361 gcaaaacatc gtataaagat attactaaaa ttcaattggc aacaacagaa aaacaaaaac
      421 tactggcttc acttgaggtc gttaacagta tgagctccta tgtggagttg ttgacggtgg
      481 gtatggatgt tgaggatagt aaacaaatta tattacttaa tcaggcgctc gatcacgcaa
      541 acaacgccca aaaactactt ggcttttcag aaggtgaaga actgactaag tcagctgtgg
      601 ctgttaaaga tttagttcaa tatttcaatg gattatacaa
//
LOCUS       DADXDL010000319          602 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.332, whole genome shotgun sequence.
ACCESSION   DADXDL010000319 DADXDL010000000
VERSION     DADXDL010000319.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 602)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 602)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..602
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.332"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>602
                     /locus_tag="IRB70_005086"
     CDS             <1..>602
                     /locus_tag="IRB70_005086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000099160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBC0634855.1"
                     /translation="LHADDTPVPVLLPGNKKTKTGRLWTYVRDDRNAGSTLAPAVWFA
                     YSPDRKGIHPQTHLAGFSGVLQADAYAGFNELYRDGRITEAACWAHARRKIHDVHVRT
                     PSALTEEALKRIGELYAIEAEIRGMTAEQRLAERQLKTKPLLKSLESWLREKMKTLSR
                     HSELAKAFAYALNQWPALTYYADDGWAEADNNIAENALRM"
BASE COUNT          143 a          165 c          192 g          102 t
ORIGIN      
        1 gctccatgct gatgacacgc ctgtcccggt gctgttgcca ggcaataaga aaacgaagac
       61 cgggcggtta tggacctacg ttcgtgacga ccgtaacgcc gggtcaacgc tggcgccggc
      121 ggtgtggttc gcttacagcc cggacagaaa aggcatccat ccgcagaccc atcttgcggg
      181 gttcagtggt gtactgcagg cggatgcata cgccgggttc aacgagctgt accgggatgg
      241 ccggataacg gaagccgcct gttgggctca cgcccgccgt aaaatccacg atgtgcacgt
      301 tcgcaccccg tcagccctga cggaggaagc gctgaaacgg atcggcgaac tgtacgccat
      361 cgaggcagag ataaggggaa tgacggcgga gcagcgcctt gccgaacgtc agttgaaaac
      421 gaaaccgctg ctgaaatccc tggaaagctg gctgcgtgaa aagatgaaaa ccctgtcgcg
      481 acactcagaa ctggcgaaag cgttcgcata cgccctgaac cagtggccgg cgctgacgta
      541 ctatgcagat gatggctggg ctgaggcgga caataacatc gctgaaaatg cgttgcggat
      601 gg
//
LOCUS       DADXDL010000320          587 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.333, whole genome shotgun sequence.
ACCESSION   DADXDL010000320 DADXDL010000000
VERSION     DADXDL010000320.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 587)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 587)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..587
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.333"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>587
                     /locus_tag="IRB70_005087"
     CDS             <1..>587
                     /locus_tag="IRB70_005087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012904571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634856.1"
                     /translation="GKSSEKLRAKTERQIQEAQERISALQEEMAETLGEQYDPVLPSA
                     LRQSSARKPLPASLPRETRVIRPEEECCPACGGELSSLGCDVSEQLELISSAFKVIET
                     QRPKQACCRCDHIVQAPVPSKPIARSYAGAGLLAHVVTGKYADHLPLYRQSEIYRRQG
                     VELSRATLGRWTGAVVELLEPLYDVLRQYVLMPGKV"
BASE COUNT          141 a          158 c          169 g          119 t
ORIGIN      
        1 ggtaaaagct cagaaaaact tcgtgcaaaa accgaacggc agatacagga agcacaggag
       61 cgaatcagcg cacttcagga agaaatggcg gaaacgctgg gtgagcaata tgacccggta
      121 ctgccatccg ccctgcgcca gtcttcagcc cgtaaaccgt taccggcctc acttccccgt
      181 gaaacccggg ttatccggcc ggaagaggaa tgctgtcctg cctgtggtgg tgaactcagt
      241 tctctgggat gtgatgtgtc agagcaactg gagcttatca gcagcgcctt taaggttatc
      301 gaaacacaac gtccgaaaca ggcctgttgc cggtgcgacc atatcgtgca ggcaccagta
      361 ccttcaaaac ccattgcacg cagttatgcc ggagcggggc ttctggccca tgttgtcacc
      421 gggaaatatg cagaccatct gccgttatac cgccagtcag aaatataccg tcgtcaggga
      481 gtggagctga gccgtgccac actggggcgc tggacaggtg ctgttgttga actgctggag
      541 ccgctgtatg acgtcctgcg ccagtatgtg ctgatgcccg gtaaagt
//
LOCUS       DADXDL010000321          572 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.334, whole genome shotgun sequence.
ACCESSION   DADXDL010000321 DADXDL010000000
VERSION     DADXDL010000321.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 572)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 572)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..572
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.334"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..263)
                     /locus_tag="IRB70_005088"
     CDS             complement(<1..263)
                     /locus_tag="IRB70_005088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001052917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 25 protein"
                     /protein_id="HBC0634857.1"
                     /translation="MNLPIYIVSLKRDIERRNKINDVFHRLNINFDFFDAIDAKDPQN
                     KEIIDKMRLSGVGAEMTDGEIACTLSHQLIYQDMIDKNIEWAV"
     gene            complement(295..>572)
                     /locus_tag="IRB70_005089"
     CDS             complement(295..>572)
                     /locus_tag="IRB70_005089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001626264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBC0634858.1"
                     /translation="YKKTITDDTKLIHYVGVTKPWNDWTNYPCQKYFNEAYQASCWND
                     VAFIPATNEKQYQVKSRHLKRNGKIASSLYYFMLYYSKKIARKHFSK"
BASE COUNT          180 a          103 c           81 g          208 t
ORIGIN      
        1 atgactgccc attctatatt tttatctatc atatcctgat atataagttg atgacttaat
       61 gtacaagcaa tttctccatc agtcatttct gcgccgacac cacttaatct cattttatca
      121 ataatttctt tattttgagg gtctttagca tctatggcat caaaaaaatc aaaattaata
      181 tttaatcgat gaaaaacatc atttatttta tttcttcgct caatatctct tttaagtgag
      241 acaatataaa tgggcaagtt cattaaaaaa tctctggatg attaatctta ataattattt
      301 ggaaaaatgc ttacgcgcta ttttcttact ataatagagc atgaaatagt aaagtgaaga
      361 tgcaattttt ccatttcttt tcaaatgtct ggatttcact tgatactgct tttcattcgt
      421 ggctggaata aacgccacat cattccagca agaagcctga taagcctcat taaaatactt
      481 ctggcaggga taattcgtcc agtcgttcca gggcttcgtt acgccaacat aatgaatcag
      541 cttagtatca tcggtaatgg tctttttata at
//
LOCUS       DADXDL010000322          569 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.335, whole genome shotgun sequence.
ACCESSION   DADXDL010000322 DADXDL010000000
VERSION     DADXDL010000322.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.335"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            54..>569
                     /gene="istA"
                     /locus_tag="IRB70_005090"
     CDS             54..>569
                     /gene="istA"
                     /locus_tag="IRB70_005090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element IS100 family transposase"
                     /protein_id="HBC0634859.1"
                     /translation="MVTFETVMEIKILHKQGMSSRAIARELGISRNTVKRYLQAKSEP
                     PKYTPRPAVASLLDEYRDYIRQRIADAHPYIIPATVIAREIRDQGYRGGMTILRAFIR
                     SLSVPQEQEPAVRFETEPGRQMQVDWGTMRNGRSPLHVFVAVLGYSRMLYIEFTDNMR
                     YDTLETCHRNAF"
BASE COUNT          139 a          146 c          145 g          139 t
ORIGIN      
        1 acgcctgaaa tcagatccag ggggtaatct gctctcctga ttcaggagag cttatggtca
       61 cttttgagac agttatggaa attaaaatcc tgcacaagca gggaatgagt agccgggcga
      121 ttgccagaga actggggatc tcccgcaata ccgttaaacg ttatttgcag gcaaaatctg
      181 agccgccaaa atatacgccg cgacctgctg ttgcttcact cctggatgaa taccgggatt
      241 atattcgtca acgcatcgcc gatgctcatc cttacataat cccggcaacg gtaatcgctc
      301 gcgagatcag agaccaggga tatcgtggcg gaatgaccat tctcagggca ttcattcgtt
      361 ctctctcggt tcctcaggag caggagcctg ccgttcggtt cgaaactgaa cccggacgac
      421 agatgcaggt tgactggggc actatgcgta atggtcgctc accgcttcac gtgttcgttg
      481 ctgttctcgg atacagccga atgctgtaca tcgaattcac tgacaatatg cgttatgaca
      541 cgctggagac ctgccatcgt aatgcgttc
//
LOCUS       DADXDL010000323          559 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.336, whole genome shotgun sequence.
ACCESSION   DADXDL010000323 DADXDL010000000
VERSION     DADXDL010000323.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 559)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 559)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..559
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.336"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>559
                     /locus_tag="IRB70_005091"
     CDS             <1..>559
                     /locus_tag="IRB70_005091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_310313.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBC0634860.1"
                     /translation="HYPAAQDCAYKFLVCEDKPGIPRPALDSWDAEYMQENRWDEESA
                     SFVPVETESDPMNVTFDKLAPEVQNAVMVKFDTCENITVDMVISAQELLQEDMATFDG
                     HIVEALMKMPEVNAMYPELKLHAIGWVKHKCIPGAKWPEIQAEMRIWKKRREGERKET
                     GKYTSVVDLARARANQQYTENSTEKI"
BASE COUNT          161 a          128 c          139 g          131 t
ORIGIN      
        1 cattatccgg ctgctcagga ctgcgcttat aaatttcttg tctgcgagga taaacccggt
       61 ataccccgcc ctgccctcga ttcctgggat gctgaatata tgcaggaaaa ccgctgggat
      121 gaggagtctg cttcctttgt cccggttgag actgaatccg atccgatgaa cgtcactttt
      181 gacaagctgg cccctgaagt acagaacgct gtcatggtta agttcgacac atgtgaaaac
      241 atcaccgttg atatggttat tagcgcacag gaattgttgc aggaagacat ggcaacattc
      301 gacggacata tcgttgaagc gttgatgaaa atgccagaag ttaacgccat gtatccggag
      361 cttaagttgc acgccattgg gtgggttaag cataaatgta ttcctggtgc taaatggccc
      421 gaaattcagg cagagatgcg catctggaaa aaacgtcgcg aaggtgaacg caaggaaacc
      481 ggaaaataca cgtctgttgt tgatctcgcc cgcgccagag ccaatcaaca gtacactgaa
      541 aattcaacag aaaaaatca
//
LOCUS       DADXDL010000324          526 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.337, whole genome shotgun sequence.
ACCESSION   DADXDL010000324 DADXDL010000000
VERSION     DADXDL010000324.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 526)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 526)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..526
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.337"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            36..>526
                     /locus_tag="IRB70_005092"
     CDS             36..>526
                     /locus_tag="IRB70_005092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416505.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634861.1"
                     /translation="MLQIVGALILLIAGFAILRLLFRALISTASALAGLILLCLFGPA
                     LLAGYITERITRLFHIRWLAGVFLTIAGMIISFMWGLDGKHIALEAHTFDSVKFILTT
                     ALAGGLLAVPLQIKNIQQNGITPEDISKEINGYYCCFYTAFFLMACSACAPLIALQYD
                     ISPS"
BASE COUNT          115 a          132 c          124 g          155 t
ORIGIN      
        1 attaacaata acatgatatt catcacggag tgactatgtt acagatagtc ggcgcgctga
       61 tcctgctgat cgcaggattt gccattcttc gccttttgtt cagagcatta atcagcacgg
      121 cttctgcgct ggcagggctc atattgctgt gtctgttcgg cccggcctta ctggctggct
      181 atatcaccga acgcataacc cggttgttcc atattcgctg gctggcaggc gtatttctga
      241 cgattgccgg aatgatcatc agcttcatgt ggggacttga tggtaaacat atcgcgctgg
      301 aggctcacac ctttgactct gtgaaattta ttctgaccac cgctctcgcc ggtggtctgc
      361 tggctgttcc cctgcagatc aaaaacattc agcagaacgg gatcacacca gaagatatca
      421 gcaaggaaat taacgggtat tactgctgtt tttatactgc ctttttcctt atggcgtgtt
      481 ctgcatgcgc accattgatc gcgttacagt acgatatttc accgtc
//
LOCUS       DADXDL010000325          525 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.338, whole genome shotgun sequence.
ACCESSION   DADXDL010000325 DADXDL010000000
VERSION     DADXDL010000325.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 525)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 525)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..525
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.338"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>525)
                     /locus_tag="IRB70_005093"
     CDS             complement(<1..>525)
                     /locus_tag="IRB70_005093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001018451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type III effector protein"
                     /protein_id="HBC0634862.1"
                     /translation="AFQSGMLKIQFPNDNEKLSVYLKNKIPFENITIDLSVLEKEALA
                     SLKYCNFKKVTFTGAISYENLNGSVFGNCFFEDCIFENVSLVSSRYRVKPNNEIPIYG
                     VFKECFLYRCEIKNFNIDTSKIYSVNQDPNVGKPVGAYLFMQSFVDECTLQDGVCKNA
                     SVIASSLLCCKIAKL"
BASE COUNT          175 a           99 c           72 g          179 t
ORIGIN      
        1 aagctttgct attttacaac ataacaaact gcttgcaata acacttgcat ttttacacac
       61 tccatcctga agagtacact catctacaaa tgactgcata aacagatatg caccaactgg
      121 cttacccaca ttgggatctt gatttacaga gtatattttt gatgtatcta tgttaaaatt
      181 ttttatttca catcgataca gaaaacactc tttaaacacg ccgtaaatag gtatttcatt
      241 atttggtttt actcgatacc tggagctaac aagtgacaca ttctcaaaaa tacagtcctc
      301 aaaaaaacaa tttccaaata ctgaaccatt aagattttcg taagatatag caccagtgaa
      361 tgtcactttt ttaaagttac aatattttag agatgccagg gcttcttttt ccagcacaga
      421 taaatcgatt gtgatatttt caaaggggat tttatttttt aaatatacgc taagcttttc
      481 attatcattt gggaactgta ttttcagcat ccctgattga aaagc
//
LOCUS       DADXDL010000326          508 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.339, whole genome shotgun sequence.
ACCESSION   DADXDL010000326 DADXDL010000000
VERSION     DADXDL010000326.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 508)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 508)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..508
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.339"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>508
                     /locus_tag="IRB70_005094"
     CDS             <1..>508
                     /locus_tag="IRB70_005094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001608780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific DNA-methyltransferase"
                     /protein_id="HBC0634863.1"
                     /translation="YERISKSYNLLKISAINFTAIDHAELYNLGKIKDEIYGEQNRIA
                     VVTVQHNPKGRNQAKFFSENTEYMLVYAKDFNAANFNSVAIDEDVLLTFTEQDNIGRY
                     RWENFIRARTSWSRANRPNNWYPLYVSSDLKSISVDYVDGYIEVYPTTKQGDFSWKNI
                     KESFVELN"
BASE COUNT          179 a           72 c           95 g          162 t
ORIGIN      
        1 tgtatgaaag gatatctaaa agctataatt tactgaaaat ttctgcaatt aattttaccg
       61 cgatagatca tgcggaatta tataatcttg gtaagatcaa ggatgaaatc tatggagaac
      121 aaaacaggat agcagttgtt actgttcagc ataatcctaa agggcgtaac caggcaaagt
      181 tcttttctga aaatactgag tatatgttag tatatgctaa agattttaat gctgctaact
      241 ttaactctgt agctatcgat gaggatgtgc ttttaacatt cacagaacaa gataatatag
      301 gccgttatcg ttgggaaaac tttattcgtg caagaacaag ttggtccaga gcaaatagac
      361 caaataactg gtatccttta tacgtctctt ccgacttaaa atcaatttct gttgattatg
      421 tagatgggta tatcgaagta tatcctacaa ctaaacaggg ggatttttcg tggaaaaata
      481 ttaaagaatc atttgttgaa ttaaataa
//
LOCUS       DADXDL010000327          498 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.340, whole genome shotgun sequence.
ACCESSION   DADXDL010000327 DADXDL010000000
VERSION     DADXDL010000327.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.340"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..498
                     /locus_tag="IRB70_005095"
     rRNA            <1..498
                     /locus_tag="IRB70_005095"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          122 a          122 c          148 g          106 t
ORIGIN      
        1 acaggtgctg catggctgtc gtcagctcgt gttgtgaaat gttgggttaa gtcccgcaac
       61 gagcgcaacc cttatccttt gttgccagcg gtccggccgg gaactcaaag gagactgcca
      121 gtgataaact ggaggaaggt ggggatgacg tcaagtcatc atggccctta cgaccagggc
      181 tacacacgtg ctacaatggc gcatacaaag agaagcgacc tcgcgagagc aagcggacct
      241 cataaagtgc gtcgtagtcc ggattggagt ctgcaactcg actccatgaa gtcggaatcg
      301 ctagtaatcg tggatcagaa tgccacggtg aatacgttcc cgggccttgt acacaccgcc
      361 cgtcacacca tgggagtggg ttgcaaaaga agtaggtagc ttaaccttcg ggagggcgct
      421 taccactttg tgattcatga ctggggtgaa gtcgtaacaa ggtaaccgta ggggaacctg
      481 cggttggatc acctcctt
//
LOCUS       DADXDL010000328          487 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.341, whole genome shotgun sequence.
ACCESSION   DADXDL010000328 DADXDL010000000
VERSION     DADXDL010000328.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.341"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..153
                     /locus_tag="IRB70_005096"
     CDS             <1..153
                     /locus_tag="IRB70_005096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634864.1"
                     /translation="AAELFSGIRHIAINILTNDKVFKAGLRRKMRKAAMDRNYLASVL
                     AGSGLS"
BASE COUNT          151 a           88 c           97 g          151 t
ORIGIN      
        1 gccgcagaat tattttcagg gatacggcac atcgctatta atattttaac gaatgataag
       61 gtattcaagg cagggttaag acgtaagatg cgaaaagctg ccatggacag aaactatctc
      121 gcgtcagtcc ttgcggggag cgggctttcg taatctttcc ctgtccttgt aacccaccag
      181 ttggagagaa attcaataaa acaacacatt atgatcatga tcatgctgaa tgcttacaga
      241 gaactggttc gaaagtgcat tggcattatc agacacataa ccaaattccc tatcctgatt
      301 gtacatgtaa acttcaaaaa catgcatttg gtgactgtgg agttgcacca ccataagtta
      361 tcaatctata ctttaaaatc ataatggatt cttatacttc cattgtgctg attgtatgtg
      421 cagtagtgag tatagatgtc atgaatatta aattttctct cgatgtttaa tatttggtga
      481 gtataat
//
LOCUS       DADXDL010000329          483 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.342, whole genome shotgun sequence.
ACCESSION   DADXDL010000329 DADXDL010000000
VERSION     DADXDL010000329.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..483
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.342"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            24..100
                     /locus_tag="IRB70_005097"
     tRNA            24..100
                     /locus_tag="IRB70_005097"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:58..60,aa:Ile,seq:gat)
     gene            143..218
                     /locus_tag="IRB70_005098"
     tRNA            143..218
                     /locus_tag="IRB70_005098"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:176..178,aa:Ala,seq:tgc)
     gene            402..>483
                     /locus_tag="IRB70_005099"
     rRNA            402..>483
                     /locus_tag="IRB70_005099"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          136 a          101 c          126 g          120 t
ORIGIN      
        1 aaaatgagca gtaaaacctc tacaggcttg tagctcaggt ggttagagcg cacccctgat
       61 aagggtgagg tcggtggttc aagtccactc aggcctacca aatttgcacc gcaaatttga
      121 agaggtttta actacatgtt atggggctat agctcagctg ggagagcgcc tgctttgcac
      181 gcaggaggtc tgcggttcga tcccgcatag ctccaccatc tctgtagtga ttaaataaaa
      241 aatacttcag agtgtacctg caaaggttca ctgcgaagtt ttgctcttta aaaatctgga
      301 tcaagctgaa aattgaaaca ctgaacaacg aaagttgttc gtgagtctct caaattttcg
      361 caacacgatg atgagtcgaa agaaacatct tcgggttgtg aggttaagcg actaagcgta
      421 cacggtggat gccctggcag tcagaggcga tgaaggacgt gctaatctgc gataagcgtc
      481 ggt
//
LOCUS       DADXDL010000330          469 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.343, whole genome shotgun sequence.
ACCESSION   DADXDL010000330 DADXDL010000000
VERSION     DADXDL010000330.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 469)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 469)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..469
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.343"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
BASE COUNT          127 a          118 c          106 g          118 t
ORIGIN      
        1 catcacaaaa ttcactttaa aaagggcggc agagcagtca cggagtaaaa ctgataccgc
       61 caaacgtcac cagaaaattg ataacagagg gcgttgcagc ggggttgtca cttaagcgta
      121 tggtcaacct gacaacccgg tgtcctcaat gggggaagga ataaccccgc catacttacc
      181 gccgcgccat ttcgcggatt gccacaaccg gaagcgcacg gtcgacgaaa atttaacgac
      241 aggctatcta tgaaccagct acctcgctgt gcgctttcgc gttatggtct gacttttcag
      301 ggaaatatcc tttcagtaaa ctgtcagtgc cggatgctca cccgtgtccg gcgcacgcac
      361 tccacctcac ctgtgaataa attaatgatt aattgatatt ttgttgtttg attcaacttt
      421 cccatcggat gtgtgatgct ttaaatcaca ggaattaata ctgcttgct
//
LOCUS       DADXDL010000331          459 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.344, whole genome shotgun sequence.
ACCESSION   DADXDL010000331 DADXDL010000000
VERSION     DADXDL010000331.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..459
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.344"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>459
                     /locus_tag="IRB70_005100"
     CDS             <1..>459
                     /locus_tag="IRB70_005100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001615228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="prophage tail fiber N-terminal domain-containing
                     protein"
                     /protein_id="HBC0634865.1"
                     /translation="AKRNSTTVLVNTVASENPDEAGRYSMDVEYGQYSVTLLVEGFPP
                     SHAGTITVYEGSRPGTLNDFLGAMTEDDVMPEALRRFEAMVEEVARNAEAASQSAAAA
                     KKSETAAASSKNAAKTSETNAANSAQAAAASQTASANSATAAKKSETNAK"
BASE COUNT          132 a          120 c          130 g           77 t
ORIGIN      
        1 ggcaaagcgt aacagcacca cggtactggt gaacacggtg gcttctgaaa atccggatga
       61 agccggacgt tacagcatgg atgttgagta tggccagtac agcgtcaccc tgctggttga
      121 aggttttccg ccttcacatg ccgggaccat taccgtctat gaaggctcca gaccaggtac
      181 gctgaatgat tttctcggtg ccatgacgga agatgatgtc atgccggagg cattgcgtcg
      241 ttttgaggca atggtggaag aagtggcacg caacgccgaa gccgcctctc agagcgcagc
      301 ggcggcaaag aaatccgaaa ctgcagcggc atcatcaaag aacgcggcga aaacctcaga
      361 aacgaatgca gctaatagtg cacaggcggc agcggcctca cagactgcat cggcaaactc
      421 cgcgacagca gccaaaaaat cagaaaccaa cgcgaaaaa
//
LOCUS       DADXDL010000332          451 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.345, whole genome shotgun sequence.
ACCESSION   DADXDL010000332 DADXDL010000000
VERSION     DADXDL010000332.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 451)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 451)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..451
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.345"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            4..451
                     /locus_tag="IRB70_005101"
                     /pseudo
     CDS             4..451
                     /locus_tag="IRB70_005101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     misc_feature    267..383
                     /locus_tag="IRB70_005101"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01497"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="AL1L pseudoknot; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /pseudo
                     /db_xref="RFAM:RF01497"
BASE COUNT          113 a          113 c          131 g           94 t
ORIGIN      
        1 gggatgataa gtttatcacc accgactatt tgcaacagtg ccctggaaag tcagggcgaa
       61 tatgactcac aatgggcggc aatttgttcc attgctccaa agactggctg tacgccggag
      121 actctgcgtg tctgggttcg ccagtatgag cgggataccg ggggcggaga tggagggctc
      181 accagtgctg aacgtcagcg tctgaaagag ctggaacgtg aaaatcgtga actgcgccgc
      241 agcaacaata tccttcgcca ggcttccgct tattttgcga aggcggagtt cgaccgcctc
      301 tggaaaaagt gatggcactg ctggataagc tgcgtgagca gtacggggtc agaccggtat
      361 gcagtgaact gcatattgcc ccgtcaacgt attaccactg tcagcaacag cgacatcatc
      421 ctgataaacg cagtgcacat gcacagcgcg a
//
LOCUS       DADXDL010000333          435 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.346, whole genome shotgun sequence.
ACCESSION   DADXDL010000333 DADXDL010000000
VERSION     DADXDL010000333.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 435)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.346"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            1..435
                     /locus_tag="IRB70_005102"
                     /pseudo
     CDS             1..435
                     /locus_tag="IRB70_005102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076612086.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
BASE COUNT           97 a          108 c          132 g           98 t
ORIGIN      
        1 cgcctcatgg cggttatggg acttgccggt gttctccggg gtaaaaaggt ccgcactacc
       61 gtcagccgga aaaccgttgc cgcaggtgac cgcgtaaacc gtcagttcgt ggcagaacgt
      121 cctgaccagc tgtgggtggc tgattttact tacgtcagca catggcaggg cttcgtctat
      181 agtggcgttc atcattgatg tatttgccgg atatatcgtg ggatggtggg tatcatcgtc
      241 catggaaacg acattcgtgc tggatgcact ggagcaggcg ttgtgggccc gtcgtccgtc
      301 cggcaccatc catcacagcg ataaaggctc tcagtatgtg tcactggcct atacggagcg
      361 actaaaagaa gcaaaactgc tggcatcaac agggagtaca ggcgactcgt atgacaacgc
      421 gatggcggag agcat
//
LOCUS       DADXDL010000334          433 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.347, whole genome shotgun sequence.
ACCESSION   DADXDL010000334 DADXDL010000000
VERSION     DADXDL010000334.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..433
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.347"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(65..>433)
                     /gene="crcB"
                     /locus_tag="IRB70_005103"
     CDS             complement(65..>433)
                     /gene="crcB"
                     /locus_tag="IRB70_005103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001318207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoride efflux transporter CrcB"
                     /protein_id="HBC0634866.1"
                     /translation="LFAVIIGGSVGCTLRWLLSTRFNSLFPNLPPGTLVVNLLAGLII
                     GTALAYFLRQPHLDPFWKLMITTGLCGGLSTFSTFSVEVFALLQAGNYIWALTSVLVH
                     VIGSLIMTALGFFIITILFA"
BASE COUNT          155 a           88 c           95 g           95 t
ORIGIN      
        1 ccatggagcg aaattctatc ctaagcgtca cattagttga taaacctgta acgttaatga
       61 attctcatgc gaaaagtatg gttatgataa aaaagcctaa agctgtcatg atgagggagc
      121 caatgacgtg aacaagtaca gacgtcaaag cccatatata atttcccgcc tggagtaatg
      181 cgaatacttc aacagaaaat gtagagaaag tactcagacc tccacaaagt cccgttgtta
      241 tcattaattt ccaaaaagga tcaaggtgtg gttgtcgtaa aaagtacgcc aacgcagtac
      301 caataattaa cccggcaagg aggttcacca ccagtgtacc tggaggtaga tttggaaaaa
      361 gactgttaaa gcgtgtggac agtaaccagc gcagagtaca tccaacagaa ccgccgataa
      421 tgacggcaaa aag
//
LOCUS       DADXDL010000335          406 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.348, whole genome shotgun sequence.
ACCESSION   DADXDL010000335 DADXDL010000000
VERSION     DADXDL010000335.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..406
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.348"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            56..>406
                     /locus_tag="IRB70_005104"
     CDS             56..>406
                     /locus_tag="IRB70_005104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416244.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634867.1"
                     /translation="MLSTNLIQSNYGDLNIKNLAFDSFKERLQSTMTALTFFISTGQC
                     ACDEIAESNFNYMIAYMSNINYDASKPGAPALSFDTYLQDNVKYRVIINNLYGSEIRI
                     RGINKDFIGMDVTSV"
BASE COUNT          142 a           59 c           73 g          132 t
ORIGIN      
        1 taaatgactt agatttaaat gagataataa ttttgttaac aatatgaggc gggagatgct
       61 ttctacaaac ttaatacaga gtaattatgg tgatttaaat attaaaaacc ttgccttcga
      121 ctcttttaaa gaaagattgc agtctaccat gacagcactc actttcttta tatcaacggg
      181 tcaatgtgcc tgcgatgaaa tagcagaatc aaacttcaat tatatgattg cctatatgtc
      241 taacattaac tatgatgcct caaagccggg agcgccagca cttagttttg atacgtatct
      301 gcaggacaat gttaaatata gagtaataat taataatctt tatggtagtg aaattcggat
      361 aagaggtata aataaagatt ttattggaat ggatgtcact tctgta
//
LOCUS       DADXDL010000336          400 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.349, whole genome shotgun sequence.
ACCESSION   DADXDL010000336 DADXDL010000000
VERSION     DADXDL010000336.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 400)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 400)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..400
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.349"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>400)
                     /locus_tag="IRB70_005105"
     CDS             complement(<1..>400)
                     /locus_tag="IRB70_005105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_311759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="YopN family type III secretion system gatekeeper
                     subunit"
                     /protein_id="HBC0634868.1"
                     /translation="GINSALKAKLFGQALSLNPKLLRASYRQFLMAEDDAVDTYVEWI
                     GSYGYQNRMLVTKFIKETLFSDINALDASCSSLEFGMFLNKLSQLLSLQSAEALFLKT
                     LMNNPIINKFISAEDYWIFFLISLIKFPETA"
BASE COUNT          135 a           76 c           59 g          130 t
ORIGIN      
        1 tgcagtctca ggaaatttta ttaacgatat cagaaaaaat atccaataat cttctgcgct
       61 aataaattta ttaattattg ggttattcat taaagttttc agaaataaag cctctgccga
      121 ctgaagagac aatagttgtg acaacttatt gagaaacata ccaaattcca atgatgaaca
      181 gctcgcatca agtgcattta tatctgagaa aagcgtctct ttgataaatt ttgtcaccag
      241 cattctattt tgatagccat aactaccaat ccattcgaca taagtatcta cagcatcgtc
      301 ttctgccatt aaaaattgtc gataacttgc ccttagtaat tttggattta atgacaacgc
      361 ctggccaaat aactttgctt ttaatgccga gttaataccg
//
LOCUS       DADXDL010000337          399 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.350, whole genome shotgun sequence.
ACCESSION   DADXDL010000337 DADXDL010000000
VERSION     DADXDL010000337.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 399)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 399)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..399
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.350"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(32..>399)
                     /locus_tag="IRB70_005106"
     CDS             complement(32..>399)
                     /locus_tag="IRB70_005106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="HBC0634869.1"
                     /translation="AAYRFLGKILNNVKKWQIPRFINTDKAPAYGRALALLKREGRCP
                     SDVEHRQIKYRNNVIECDHGKLKRIIGATLGFKSMKTAYATIKGIEVMRALRKGQASA
                     FYYGDPLGEMRLVSRVFEM"
BASE COUNT           85 a          104 c           98 g          112 t
ORIGIN      
        1 atgaggcagc cttttgtctt attcaaaggc cttacatttc aaaaactctg cttaccaggc
       61 gcatttcgcc caggggatca ccataataaa atgctgaggc ctggcctttg cgtagtgcac
      121 gcatcacctc aatacctttg atggtggcgt aagccgtctt catggattta aatcccagcg
      181 tggcgccgat tatccgtttc agtttgccat gatcgcattc aatcacgttg ttccggtact
      241 taatctgtcg gtgttcaacg tcagacgggc accggccttc gcgtttgagc agagcaagcg
      301 cgcgaccata ggcgggcgct ttatccgtgt tgatgaatcg cgggatctgc cacttcttca
      361 cgttgttgag gattttaccc agaaaccggt atgcagctt
//
LOCUS       DADXDL010000338          392 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.351, whole genome shotgun sequence.
ACCESSION   DADXDL010000338 DADXDL010000000
VERSION     DADXDL010000338.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 392)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 392)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..392
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.351"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>392
                     /locus_tag="IRB70_005107"
     CDS             <1..>392
                     /locus_tag="IRB70_005107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001341848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="PrgH/EprH family type III secretion apparatus
                     protein"
                     /protein_id="HBC0634870.1"
                     /translation="LSQDLLESYAIRLLSGPLNGCEYEILNGRVLVIVGNDVSLGRSD
                     SFSELPENTIVIPYGELTGSFEVIITTDPDLVVTIRELTAQEPEDRTLTLNQQIEVLG
                     LKFAVKGKNEVWQYSIPGIVENNITSTR"
BASE COUNT          130 a           61 c           83 g          118 t
ORIGIN      
        1 cttatcacaa gacttattgg aatcttatgc cattcgttta ttgagcggac cattgaatgg
       61 atgcgagtat gaaatactta atgggcgtgt actcgttatc gttggtaatg atgtttcgtt
      121 aggaagaagt gattcttttt ctgagttacc agagaatacg atagtcattc cttatggaga
      181 gcttacaggc agttttgagg taataatcac taccgaccct gatctggttg taacaatcag
      241 agaattaaca gcacaagaac ctgaagatag aacgttaaca ttgaatcagc aaatagaagt
      301 tttaggcctc aaatttgctg taaaaggaaa aaatgaagtt tggcagtatt caataccagg
      361 tattgttgaa aataacatta cttcaacaag gc
//
LOCUS       DADXDL010000339          387 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.352, whole genome shotgun sequence.
ACCESSION   DADXDL010000339 DADXDL010000000
VERSION     DADXDL010000339.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..387
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.352"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..341)
                     /locus_tag="IRB70_005108"
     CDS             complement(<1..341)
                     /locus_tag="IRB70_005108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_706683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase domain-containing protein"
                     /protein_id="HBC0634871.1"
                     /translation="MFPDFFMHIGQALDLVSRYDSLRNPLTSLGDYLDPELISRCLAE
                     SGTVTLRKRRLPLEMMVWCIVGMALERKEPLHQIVNRLDIMLPGNRPFVAPSAVIQAR
                     QRLGSEAVRRV"
BASE COUNT          106 a           98 c          113 g           70 t
ORIGIN      
        1 aacacgcggc ggacagcctc acttcccagg cgctggcggg cctgaataac ggcactgggg
       61 gcaacgaagg ggcgattgcc cggcagcatg atgtccaggc gattcacaat ctggtgaaga
      121 ggttctttac gctcaagcgc catgccaaca atacaccaga ccatcatttc gaggggaaga
      181 cggcgcttgc gtagcgttac agtacctgat tcggcaaggc aacgagagat gagttcgggg
      241 tcgaggtaat cccccagaga agtcagtggg ttacgcagag aatcgtaacg ggataccaga
      301 tcaagagcct gtccaatgtg cataaaaaaa tccggaaaca agtgagcgtt tccggattct
      361 tacacagcca ctggatcggt caactga
//
LOCUS       DADXDL010000340          372 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.353, whole genome shotgun sequence.
ACCESSION   DADXDL010000340 DADXDL010000000
VERSION     DADXDL010000340.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..372
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.353"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>372
                     /locus_tag="IRB70_005109"
     CDS             <1..>372
                     /locus_tag="IRB70_005109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBC0634872.1"
                     /translation="NGIIVGRDRLARLRKELRLRCKQKRKFRATTNSNHNLPVAPNLL
                     NQTFAPTAPNQVWVADLTYVATQEGWLYLAGIKDVYTCEIVGYAMGERMTKELTGKAL
                     FMALRSQRPPAGLIHHSDRGS"
BASE COUNT           95 a          100 c          102 g           75 t
ORIGIN      
        1 gaatggcatc atcgttggtc gtgaccgact ggcacgtctt cgtaaggagc taaggctacg
       61 ctgtaagcag aaacgcaagt tcagagcgac tacgaactcg aaccacaatc tgccagttgc
      121 gccaaatctg ctgaaccaga cgttcgctcc tacagcacca aatcaggtct gggtggcgga
      181 cctgacgtat gttgccacac aggagggatg gttgtacctc gctggcatca aagatgttta
      241 tacgtgcgaa attgtcggct acgccatggg agagcgcatg acaaaagagc tgacaggtaa
      301 agccctgttt atggcgctca ggagccagcg cccacctgcc gggctaatcc accactctga
      361 tcgaggttca ca
//
LOCUS       DADXDL010000341          361 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.354, whole genome shotgun sequence.
ACCESSION   DADXDL010000341 DADXDL010000000
VERSION     DADXDL010000341.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 361)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 361)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..361
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.354"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(11..331)
                     /gene="trbA"
                     /locus_tag="IRB70_005110"
     CDS             complement(11..331)
                     /gene="trbA"
                     /locus_tag="IRB70_005110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001464974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TrbA"
                     /protein_id="HBC0634873.1"
                     /translation="MTCLFAPSLIFVIIAGYFFSERNDRKMFLLSSLVFLVINIACLY
                     VLTASLWFLCGAIMNQGAAMVVPMVIGSLPNVTSFDRFRRIFICIMLSSAWSGVMWFF
                     IRGL"
BASE COUNT          132 a           84 c           64 g           81 t
ORIGIN      
        1 acttagcctg tcataagccc cttataaaaa accacatcac tccggaccat gctgatgaca
       61 acataataca gataaatatt cttctgaacc tgtcgaagct cgtaacgttc ggtaatgagc
      121 caataaccat tggaacaacc attgctgcgc cctgattcat aattgcacca cacagaaacc
      181 agagactggc ggtaagcaca tataaacacg cgatattaat aacaaggaaa accagtgagc
      241 tcaggagaaa cattttcctg tcattacgct cagaaaagaa ataaccggca ataatgacaa
      301 atattaagga aggtgcgaat aagcaggtca tttcttccca agctgactcg ctgattaaaa
      361 t
//
LOCUS       DADXDL010000342          355 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.355, whole genome shotgun sequence.
ACCESSION   DADXDL010000342 DADXDL010000000
VERSION     DADXDL010000342.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 355)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 355)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..355
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.355"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            41..328
                     /locus_tag="IRB70_005111"
     CDS             41..328
                     /locus_tag="IRB70_005111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001825190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634874.1"
                     /translation="MSTRNIHVNTASYTLLVAGKKKNTGEEWDVLEFSSLTELKKYRK
                     SHPEKMAFSYSYALSQGVDKQFRHINIAEADHFKQFLRQIKRAGLDIRAIC"
BASE COUNT          104 a           86 c           97 g           68 t
ORIGIN      
        1 agatgatggg ggctgaaaac cagagagagg agaaagcagg atgagtaccc gaaatatcca
       61 cgttaacacc gcgtcgtaca cgcttcttgt tgccgggaag aaaaaaaaca ccggggaaga
      121 gtgggacgtc ctggaattca gcagcctgac tgagctgaaa aaatatcgca aaagccaccc
      181 ggaaaagatg gccttcagtt atagctacgc gctcagtcag ggtgtggata agcagttccg
      241 ccatatcaac attgcggaag ccgatcactt caaacagttc ctgcgtcaga ttaagcgtgc
      301 cggcctcgat atccgggcga tctgctgacc ggatgtgatg aatacccctc ctgat
//
LOCUS       DADXDL010000343          296 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.357, whole genome shotgun sequence.
ACCESSION   DADXDL010000343 DADXDL010000000
VERSION     DADXDL010000343.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 296)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 296)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..296
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.357"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>296
                     /locus_tag="IRB70_005112"
     CDS             <1..>296
                     /locus_tag="IRB70_005112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBC0634875.1"
                     /translation="REYKQTWKTLDDELAYALWPGDVDAGNIDGSIHRWAKNEVIDND
                     REDWKRISASMRKQPDALRYDRQTIFGLVRERPIDIHKDPVALNKYITEYLTTK"
BASE COUNT           87 a           79 c           71 g           59 t
ORIGIN      
        1 tcgcgaatac aagcagacat ggaaaacact ggatgacgaa ctggcctacg ctctctggcc
       61 tggtgatgtg gatgccggaa acattgacgg cagcatccat cgctgggcaa aaaatgaagt
      121 tatcgacaac gaccgcgaag actggaagcg tatctcggca tcaatgcgca aacagcctga
      181 tgcccttcgc tacgaccgcc agactatttt tggccttgtc cgtgaacgtc cgatcgacat
      241 tcacaaagac cctgtggcac tgaacaaata cattactgaa tacctgacta caaagg
//
LOCUS       DADXDL010000344          294 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.358, whole genome shotgun sequence.
ACCESSION   DADXDL010000344 DADXDL010000000
VERSION     DADXDL010000344.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..294
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.358"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>294)
                     /locus_tag="IRB70_005113"
     CDS             complement(<1..>294)
                     /locus_tag="IRB70_005113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004020115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634876.1"
                     /translation="FIALDGNGRLTGARTAQAAPYANYTCHLCGSALRYHPQYDTELP
                     WFEHTDDRLTEHGQQCPYVRPERREIQLIKRLQQFVPDALPVVRKASWHCRQC"
BASE COUNT           62 a           73 c           87 g           72 t
ORIGIN      
        1 gacattgtct gcagtgccag ctggctttac gcaccacggg taaggcatcc ggtacgaatt
       61 gctgcagacg tttaatcaac tgtatttctc tgcgctccgg cctgacataa gggcactgtt
      121 gaccgtgctc tgtcagcctg tcgtcagtgt gttcaaacca gggaagttca gtgtcgtatt
      181 gcggatggta tctgagtgca ctgccacaca agtggcaggt gtagttagca taaggtgcgg
      241 cctgtgcagt acgggcgccc gtcagacgtc cgttgccatc aagagcgata aagg
//
LOCUS       DADXDL010000345          293 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.359, whole genome shotgun sequence.
ACCESSION   DADXDL010000345 DADXDL010000000
VERSION     DADXDL010000345.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 293)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 293)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..293
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.359"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>293
                     /locus_tag="IRB70_005114"
     CDS             <1..>293
                     /locus_tag="IRB70_005114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS6-like element IS26 family transposase"
                     /protein_id="HBC0634877.1"
                     /translation="NPFKGRHFQRDIILWAVRWYCKYGISYRELQEMLAERGVNVDHS
                     TIYRWVQRYAPEMEKRLRWYWRNPSDLCPWHMDETYVKVNGRWAYLYRAVDSR"
BASE COUNT           63 a           77 c           87 g           66 t
ORIGIN      
        1 tgaacccatt caaaggccgg cattttcagc gtgacatcat tctgtgggcc gtacgctggt
       61 actgcaaata cggcatcagt taccgtgagc tgcaggagat gctggctgaa cgcggagtga
      121 atgtcgatca ctccacgatt taccgctggg ttcagcgtta tgcgcctgaa atggaaaaac
      181 ggctgcgctg gtactggcgt aacccttccg atctttgccc gtggcacatg gatgaaacct
      241 acgtgaaggt caatggccgc tgggcgtatc tgtaccgggc cgtcgacagc cgg
//
LOCUS       DADXDL010000346          287 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.360, whole genome shotgun sequence.
ACCESSION   DADXDL010000346 DADXDL010000000
VERSION     DADXDL010000346.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..287
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.360"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
BASE COUNT           50 a           98 c           80 g           59 t
ORIGIN      
        1 cctctgtcgc gccgtggcct gcgctcctgg catcccggca aaagaccgcc gggatgtaag
       61 gggcaacgcc gtttcgcaaa ccgcgcttca cgtcgttgcg gcgggtccct gcccgttgtt
      121 ctgtccggtg ccattcacct gtttaagccc ctgtcgccgg gggcaaagac agccacaacc
      181 gtctccgcca gtccaggggt gaaatgtaca tcccgcaaaa ctttttgccc agaagcaggc
      241 aaaaactttt gcggtctgcc cccggacagt cgtttccgtc cgtggca
//
LOCUS       DADXDL010000347          281 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.361, whole genome shotgun sequence.
ACCESSION   DADXDL010000347 DADXDL010000000
VERSION     DADXDL010000347.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 281)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 281)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..281
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.361"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..251)
                     /locus_tag="IRB70_005115"
     CDS             complement(<1..251)
                     /locus_tag="IRB70_005115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_309432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system YeeU family
                     antitoxin"
                     /protein_id="HBC0634878.1"
                     /translation="MSDTLSGTTHPDDNDDHPWWGLPCTVTPCFGARLVQEGNRLHYL
                     ADRAGIRGRFRDADAYPLDQAFPLLMKQLKLMLTSGELNP"
BASE COUNT           66 a           75 c           80 g           60 t
ORIGIN      
        1 ggattcagtt caccactggt gagcattaat ttcagttgtt tcatcagcag cggaaaggcc
       61 tggtccagag ggtacgcatc cgcatctctg aaccggcctc tgataccggc acggtcggca
      121 aggtaatgca accggttacc ctcctgcacc agacgggcgc cgaaacaggg cgtcactgtg
      181 cagggtagtc cccaccaggg atggtcgtca ttgtcatcgg gatgcgttgt cccggaaagt
      241 gtgtctgaca cgataaaatc ctcacagaaa atcggtgaat g
//
LOCUS       DADXDL010000348          278 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.362, whole genome shotgun sequence.
ACCESSION   DADXDL010000348 DADXDL010000000
VERSION     DADXDL010000348.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 278)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 278)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..278
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.362"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            62..>278
                     /locus_tag="IRB70_005116"
     CDS             62..>278
                     /locus_tag="IRB70_005116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000998048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBC0634879.1"
                     /translation="MNDISSDDIFLLKQRLAEQEALIHALQEKLSNREREIDHLQAQL
                     DKLRRMNFGSRSEKVSRRIAQMEADLNR"
BASE COUNT           76 a           80 c           69 g           53 t
ORIGIN      
        1 accatgctgt aaatctcttt atcctggttg tcacagaata agcccggtaa aatacgggct
       61 tatgaacgac atctcttctg acgacatctt cctgctgaaa cagcgcctgg ccgaacagga
      121 agcgctgatc cacgccctgc aggaaaagct gagcaaccgg gagcgcgaaa tagaccatct
      181 gcaggcgcag ctggataaac tccgccggat gaacttcggc agtcgttccg aaaaagtctc
      241 ccgccgtatc gcacaaatgg aagccgatct gaaccggc
//
LOCUS       DADXDL010000349          272 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.363, whole genome shotgun sequence.
ACCESSION   DADXDL010000349 DADXDL010000000
VERSION     DADXDL010000349.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..272
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.363"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>272)
                     /locus_tag="IRB70_005117"
     rRNA            complement(<1..>272)
                     /locus_tag="IRB70_005117"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT           55 a           94 c           55 g           68 t
ORIGIN      
        1 tttccggatt tgcctggaaa accagcctac acgcttaaac cgggacaacc gtcgcccggc
       61 caacatagcc ttctccgtcc ccccttcgca gtaacaccaa gtacaggaat attaacctgt
      121 ttcccatcga ctacgccttt cggcctcgcc ttaggggtcg actcaccctg ccccgattaa
      181 cgttggacag gaacccttgg tcttccggcg agcgggcttt tcacccgctt tatcgttact
      241 tatgtcagca ttcgcacttc tgatacctcc ag
//
LOCUS       DADXDL010000350          269 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.364, whole genome shotgun sequence.
ACCESSION   DADXDL010000350 DADXDL010000000
VERSION     DADXDL010000350.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 269)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 269)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..269
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.364"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>269)
                     /locus_tag="IRB70_005118"
     CDS             complement(<1..>269)
                     /locus_tag="IRB70_005118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000907441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="invasin"
                     /protein_id="HBC0634880.1"
                     /translation="DNGATVAPTVTTQPDGTVEISVTSQTAGISAVTASINSSSQSQN
                     VTFVADVRTAKIADLVVIKDGSEADGSTANTLRVRVTDAFGNALNG"
BASE COUNT           43 a           94 c           71 g           61 t
ORIGIN      
        1 ccattcagcg cattcccgaa cgcatcggtg accctcaccc gcagcgtgtt cgccgtcgaa
       61 ccgtccgcct ctgaaccgtc cttaatgacc accagatcag cgatcttcgc cgtcctgaca
      121 tcggcgacaa acgtcacgtt ctgactctga ctgctgctgt tgatgctggc agtgactgca
      181 ctgattcctg ccgtctggct ggtgacagag atctccaccg tcccgtccgg ctgcgtggtg
      241 accgtcggag cgaccgttgc gccgttgtc
//
LOCUS       DADXDL010000351          268 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.365, whole genome shotgun sequence.
ACCESSION   DADXDL010000351 DADXDL010000000
VERSION     DADXDL010000351.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 268)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 268)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..268
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.365"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..>268)
                     /locus_tag="IRB70_005119"
     CDS             complement(<1..>268)
                     /locus_tag="IRB70_005119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000420980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISAs1 family transposase"
                     /protein_id="HBC0634881.1"
                     /translation="EHISVIPEYRQAWKVEHKLSDILLLTICAVISGAEGWEDIEDFG
                     ETHLDFLKQYGDFENGIPVHDTIARVVSCISPAKFHECFINWMRD"
BASE COUNT           89 a           62 c           44 g           73 t
ORIGIN      
        1 agtcacgcat ccagttaata aagcactcgt gaaattttgc aggactgata caggatacaa
       61 ctctggcaat ggtatcgtga acaggaatac cattttcaaa atcaccatat tgcttcaaaa
      121 aatcgagatg tgtttcccca aaatcctcta tatcttccca gccttctgca ccagaaataa
      181 cggcacaaat agtcaacagt agaatatccg acaatttatg ttccactttc caggcttgtc
      241 tgtactcggg aataacagaa atatgttc
//
LOCUS       DADXDL010000352          262 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.366, whole genome shotgun sequence.
ACCESSION   DADXDL010000352 DADXDL010000000
VERSION     DADXDL010000352.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 262)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 262)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..262
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.366"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
BASE COUNT           63 a           64 c           77 g           58 t
ORIGIN      
        1 caggcaacag ccgtcccggt acgggcagcg tggtcagggt gtgaatggcg gttcagttaa
       61 aatctggact ggagtttggg taaagcaggc tggttgctgt tacagcactg tggttgtcac
      121 acaatggaac actgacgtaa aaaacagtca gtgggcgagt ggatacatcg ttgccgccag
      181 acaacaaccc atacttttgg tttgccggat attggcgcgc cagtcgtgct caactccggc
      241 tacagccaaa attgcgctca cc
//
LOCUS       DADXDL010000353          233 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.denovo.369, whole genome shotgun sequence.
ACCESSION   DADXDL010000353 DADXDL010000000
VERSION     DADXDL010000353.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 233)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 233)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..233
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.denovo.369"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..>233
                     /locus_tag="IRB70_005120"
     CDS             <1..>233
                     /locus_tag="IRB70_005120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_312217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBC0634882.1"
                     /translation="AHVDCPGHADYVKNMITGAAQMDGAILVVAATDGPMPQTREHIL
                     LGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVR"
BASE COUNT           52 a           59 c           72 g           50 t
ORIGIN      
        1 gcacacgtag actgcccggg gcacgccgac tatgttaaaa acatgatcac cggtgctgct
       61 cagatggacg gcgcgatcct ggtagttgct gcgactgacg gcccgatgcc gcagactcgt
      121 gagcacatcc tgctgggtcg tcaggtaggc gttccgtaca tcatcgtgtt cctgaacaaa
      181 tgcgacatgg ttgatgacga agagctgctg gaactggttg aaatggaagt tcg
//
LOCUS       DADXDL010000354         3370 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.207, whole genome shotgun sequence.
ACCESSION   DADXDL010000354 DADXDL010000000
VERSION     DADXDL010000354.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 3370)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3370)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3370
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.207"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..660
                     /locus_tag="IRB70_005121"
     CDS             <1..660
                     /locus_tag="IRB70_005121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_418578.1"
                     /note="part of four member fumarate reductase enzyme
                     complex FrdABCD which catalyzes the reduction of fumarate
                     to succinate during anaerobic respiration; FrdAB are the
                     catalytic subcomplex consisting of a flavoprotein subunit
                     and an iron-sulfur subunit, respectively; FrdCD are the
                     membrane components which interact with quinone and are
                     involved in electron transfer; the catalytic subunits are
                     similar to succinate dehydrogenase SdhAB; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="succinate dehydrogenase/fumarate reductase
                     flavoprotein subunit"
                     /protein_id="HBC0634883.1"
                     /translation="VGLHGANRLGSNSLAELVVFGRLAGEQAMERASTAGNGNEAAIE
                     AQAAGVEQHLKDLVNQDGGENWAKIRDEMGMAMEEGCGIYRTPELMQKTIDKLAELQE
                     RFKRVRITDTSSVFNTDLLYTIELGHGLNVAECMAHSAMARKESRGAHQRLDEGCTER
                     DDVNFLKHTLAFRDADGTTRLEYSDVKITTLPPAKRVYGGEADAADKAEAANKKEKAN
                     G"
     gene            653..1387
                     /gene="frdB"
                     /locus_tag="IRB70_005122"
     CDS             653..1387
                     /gene="frdB"
                     /locus_tag="IRB70_005122"
                     /EC_number="1.3.5.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_020882957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase iron-sulfur protein"
                     /protein_id="HBC0634884.1"
                     /translation="MAEMKNLKIEVVRYNPEVDTAPHSAFYEVPYDATTSLLDALGYI
                     KDNLAPDLSYRWSCRMAICGSCGMMVNNVPKLACKTFLRDYTDGMKVEALANFPIERD
                     LVVDMTHFIESLEAIKPYIIGNSRTADQGTNIQTPAQMAKYHQFSGCINCGLCYAACP
                     QFGLNPEFIGPAAITLAHRYNEDSRDHGKKERMAQLNSQNGVWSCTFVGYCSEVCPKH
                     VDPAAAIQQGKVESSKDFLIATLKPR"
     gene            1398..1793
                     /gene="frdC"
                     /locus_tag="IRB70_005123"
     CDS             1398..1793
                     /gene="frdC"
                     /locus_tag="IRB70_005123"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdC"
                     /protein_id="HBC0634885.1"
                     /translation="MTTKRKPYVRPMTSTWWKKLPFYRFYMLREGTAVPAVWFSIELI
                     FGLFALKNGPEAWAGFVDFLQNPVIVIINLITLAAALLHTKTWFELAPKAANIIVKDE
                     KMGPEPIIKSLWAVTVVATIVILFVALYW"
     gene            1804..2163
                     /gene="frdD"
                     /locus_tag="IRB70_005124"
     CDS             1804..2163
                     /gene="frdD"
                     /locus_tag="IRB70_005124"
                     /EC_number="1.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_313159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fumarate reductase subunit FrdD"
                     /protein_id="HBC0634886.1"
                     /translation="MINPNPKRSDEPVFWGLFGAGGMWSAIIAPVMILLVGILLPLGL
                     FPGDALSYERVLAFAQSFIGRVFLFLMIVLPLWCGLHRMHHAMHDLKIHVPAGKWVFY
                     GLAAILTVVTLIGVVTI"
     gene            2226..3359
                     /locus_tag="IRB70_005125"
     CDS             2226..3359
                     /locus_tag="IRB70_005125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BlaEC family class C beta-lactamase"
                     /protein_id="HBC0634887.1"
                     /translation="MFKTTLCTLLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGM
                     AVAVIYQGKPYYFTWGYADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLS
                     DPTTKYWPELTAKQWNGITLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAP
                     GTQRLYANSSIGLFGALAVKPSGLSFEQAMKTRVFQPLKLNHTWINVLSAEEKNYAWG
                     YREGKAVHVSPGALDAEAYGVKSTIEDMARWVQSNLKPFDINEKTLQQGIQLAQSRYW
                     QTGDMYQGLGWEMLDWPLNPDIIINGSDNKIALAARPVKPITPPTPAVRASWVHKTGA
                     TGGFGSYVAFIPEKELGIVMLANKNYPNPARVAAAWQILNALQ"
BASE COUNT          842 a          874 c          898 g          756 t
ORIGIN      
        1 gttggtctgc acggtgcgaa ccgtctgggc tccaactcgc tggcggaact ggtggtcttc
       61 ggtcgtctgg ccggtgagca agctatggaa cgcgcatcta ctgccggtaa tggcaacgaa
      121 gcggcaattg aagcgcaggc agctggcgtt gaacaacatc tgaaagatct ggttaaccag
      181 gatggcggcg aaaactgggc taagatccgc gacgaaatgg gcatggccat ggaagaaggc
      241 tgcggtatct accgtacgcc agaactgatg cagaaaacca tcgacaagct ggcagaattg
      301 caggaacgct tcaagcgcgt gcgcatcacc gacacttcca gcgtgttcaa caccgacctg
      361 ctctacacca ttgaactggg ccacggtctg aacgttgctg aatgtatggc gcactccgca
      421 atggcacgta aagagtctcg cggcgcgcac cagcgtctgg acgaaggttg caccgagcgt
      481 gacgacgtca acttcctcaa acacaccctc gccttccgcg atgctgatgg cacgactcgc
      541 ctggagtaca gcgacgtgaa gattactacg ctgccgccag ctaaacgcgt ttacggtggc
      601 gaagcggatg cagccgataa ggcggaagca gccaataaga aggagaaggc gaatggctga
      661 gatgaaaaac ctgaaaattg aggtggtgcg ctataacccg gaagtcgata ccgcaccgca
      721 tagcgcattc tatgaagtgc cttatgacgc aactacctca ttactggatg cgctgggcta
      781 catcaaagac aacctggcac cggacctgag ctaccgctgg tcctgccgta tggcgatttg
      841 tggttcctgc ggcatgatgg ttaacaacgt gccaaaactg gcatgtaaaa ccttcctgcg
      901 tgattacacc gacggtatga aggttgaagc gttagctaac ttcccgattg aacgcgatct
      961 ggtggtcgat atgacccact tcatcgaaag tctggaagcg atcaaaccgt acatcatcgg
     1021 caactcccgc accgcggatc agggtactaa catccagacc ccggcgcaga tggcgaagta
     1081 tcaccagttc tccggttgca tcaactgtgg tctgtgctac gccgcgtgcc cgcagtttgg
     1141 cctgaaccct gagttcatcg gtccggctgc cattacgctg gcgcatcgtt ataacgaaga
     1201 tagccgcgac cacggtaaga aggagcgtat ggcgcagttg aacagccaga acggcgtatg
     1261 gagctgtact ttcgtgggct actgctccga agtctgcccg aaacacgtcg atccggctgc
     1321 ggccattcag cagggcaaag tagaaagttc gaaagacttt cttatcgcga ccctgaaacc
     1381 acgctaagga gtgcaacatg acgactaaac gtaaaccgta tgtacggcca atgacgtcca
     1441 cctggtggaa aaaattgccg ttttatcgct tttacatgct gcgcgaaggc acggcggttc
     1501 cggctgtgtg gttcagcatt gaactgattt tcgggctgtt tgccctgaaa aatggcccgg
     1561 aagcctgggc gggattcgtc gactttttac aaaacccggt tatcgtgatc attaacctga
     1621 tcactctggc ggcagccctg ctgcacacca aaacctggtt tgagctggca ccaaaagcag
     1681 ccaatatcat tgtaaaagac gaaaaaatgg gaccagagcc aattatcaaa agtctctggg
     1741 cggtaactgt ggttgccacc atcgtaatcc tgtttgttgc cctgtactgg taaggagcct
     1801 gagatgatta atccaaatcc aaagcgttct gacgaaccgg tattctgggg cctcttcggg
     1861 gccggtggta tgtggagcgc aattattgcg ccggtgatga tcctgctggt tggtattctg
     1921 ctgccactgg ggctatttcc gggtgatgcg ctgagctacg agcgcgttct ggcgttcgcg
     1981 cagagcttca ttggtcgcgt attcctgttc ctgatgatcg ttctgccgct gtggtgtggt
     2041 ttacaccgta tgcaccacgc gatgcacgat ctgaaaatcc acgtacctgc gggtaaatgg
     2101 gttttctacg gtctggctgc tatcctgaca gttgtcacac tgattggtgt cgttacaatc
     2161 taacgcatcg ccaatgtaaa tccggcccgc ctatggcgga ccgttttgta tggaaaccag
     2221 accttatgtt caaaacgacg ctctgcacct tattaattac cgcctcttgc tccacatttg
     2281 ccgcccctca acaaatcaac gatattgtgc atcgcacaat taccccgctt atagagcaac
     2341 aaaagatccc cggtatggcg gtggcggtaa tttatcaggg taaaccttat tactttacct
     2401 ggggctatgc ggacatcgcc aaaaagcagc ccgtcacaca gcaaacgttg tttgagttag
     2461 gttcggtcag caaaacattt acgggcgtgc ttggtggcga cgctattgct cgaggggaaa
     2521 tcaagttaag cgatcccaca acaaaatact ggcctgaact taccgctaaa cagtggaatg
     2581 ggatcacact attacatctc gcaacctaca ccgctggcgg cctgccattg caggtgccgg
     2641 atgaggtgaa atcctcaagc gacttgctgc gcttctatca aaactggcag cctgcatggg
     2701 ctccaggaac acaacgtctg tatgccaact ccagtatcgg tttgttcggc gcactggctg
     2761 tgaagccgtc tggtttgagt tttgagcagg cgatgaaaac tcgtgtcttc cagccactca
     2821 aactcaatca tacgtggatt aatgtactgt ccgcagaaga aaagaactac gcctggggat
     2881 atcgcgaagg taaggcagta catgtttcgc caggggcgtt agatgctgaa gcttatggtg
     2941 tgaagtcgac cattgaagat atggcccgct gggtgcaaag caatttaaaa ccatttgata
     3001 tcaatgagaa aacacttcaa caagggatac aactggcaca atctcgctac tggcaaaccg
     3061 gcgatatgta tcagggtctg ggctgggaaa tgctggactg gccgctaaat cctgacatca
     3121 tcattaacgg cagtgacaat aaaattgcac tggcagcacg ccccgtaaaa ccgattacgc
     3181 ccccaactcc tgcagtacgc gcatcatggg tacataaaac gggggcgacc ggcggatttg
     3241 gtagctatgt cgcgtttatt ccagaaaaag agctgggtat cgtgatgctg gctaacaaaa
     3301 actatcccaa tccagcgaga gtcgccgccg cctggcagat tctcaacgct ctacagtaaa
     3361 atttcatcgg
//
LOCUS       DADXDL010000355         2851 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.220, whole genome shotgun sequence.
ACCESSION   DADXDL010000355 DADXDL010000000
VERSION     DADXDL010000355.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2851)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2851)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2851
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.220"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            262..921
                     /locus_tag="IRB70_005126"
     CDS             262..921
                     /locus_tag="IRB70_005126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011152976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type A-1 chloramphenicol O-acetyltransferase"
                     /protein_id="HBC0634888.1"
                     /translation="MEKKITGYTTVDISQWHRKEHFEAFQSVAQCTYNQTVQLDITAF
                     LKTVKKNKHKFYPAFIHILARLMNAHPEFRMAMKDGELVIWDSVHPCYTVFHEQTETF
                     SSLWSEYHDDFRQFLHIYSQDVACYGENLAYFPKGFIENMFFVSANPWVSFTSFDLNV
                     ANMDNFFAPVFTMGKYYTQGDKVLMPLAIQVHHAVCDGFHVGRMLNELQQYCDEWQGG
                     A"
     gene            complement(1122..1499)
                     /locus_tag="IRB70_005127"
     CDS             complement(1122..1499)
                     /locus_tag="IRB70_005127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000656306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBC0634889.1"
                     /translation="MKDYLCKKLFNRLSGTLVIRARCGNNITGLACCNILYPSPRYSG
                     QLHIKELYVSQCDRNKGTGKAIMRFIARLALEQECLSLSWNAEKSNPGANRFYQALGG
                     RINDHIVNYYLHGESLSKLASGI"
     gene            complement(1566..>2851)
                     /locus_tag="IRB70_005128"
     CDS             complement(1566..>2851)
                     /locus_tag="IRB70_005128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001138064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="Tn3-like element TnAs3 family transposase"
                     /protein_id="HBC0634890.1"
                     /translation="AQALIDQTAMVLPHVKITELLLEVDEWTGFTRHFTHLKSGDLAK
                     DKNLLLTTILADAINLGLTKMAESCPGTTYAKLAWLQAWHTRDETYSTALAELVNAQF
                     RHPFAGHWGDGTTSSSDGQNFRTASKAKSTGHINPKYGSSPGRTFYTHISDQYAPFHT
                     KVVNVGLRDSTYVLDGLLYHESDLRIEEHYTDTAGFTDHVFALMHLLGFRFAPRIRDL
                     GDTKLYIPKGDAAYDALKPMIGGTLNIKHVRAHWDEILRLATSIKQGTVTASLMLRKL
                     GSYPRQNGLAVALRELGRIERTLFILDWLQSVELRRRVHAGLNKGEARNALARAVFFN
                     RLGEIRDRSFEQQRYRASGLNLVTAAIVLWNTVYLERAAHALRGNGHAVDDSLLQYLS
                     PLGWEHINLTGDYLWRSSAKIGAGKFRPLRPLQPA"
BASE COUNT          639 a          726 c          801 g          685 t
ORIGIN      
        1 accatcatac actaaatcag taagttggca gcatcacccg acgcactttg cgccgaataa
       61 atacctgtga cggaagatca cttcgcagaa taaataaatc ctggtgtccc tgttgatacc
      121 gggaagccct gggccaactt ttggcgaaaa tgagacgttg atcggcacgt aagaggttcc
      181 aactttcacc ataatgaaat aagatcacta ccgggcgtat tttttgagtt atcgagattt
      241 tcaggagcta aggaagctaa aatggagaaa aaaatcactg gatataccac cgttgatata
      301 tcccaatggc atcgtaaaga acattttgag gcatttcagt cagttgctca atgtacctat
      361 aaccagaccg ttcagctgga tattacggcc tttttaaaga ccgtaaagaa aaataagcac
      421 aagttttatc cggcctttat tcacattctt gcccgcctga tgaatgctca tccggaattc
      481 cgtatggcaa tgaaagacgg tgagctggtg atatgggata gtgttcaccc ttgttacacc
      541 gttttccatg agcaaactga aacgttttca tcgctctgga gtgaatacca cgacgatttc
      601 cggcagtttc tacacatata ttcgcaagat gtggcgtgtt acggtgaaaa cctggcctat
      661 ttccctaaag ggtttattga gaatatgttt ttcgtctcag ccaatccctg ggtgagtttc
      721 accagttttg atttaaacgt ggccaatatg gacaacttct tcgcccccgt tttcaccatg
      781 ggcaaatatt atacgcaagg cgacaaggtg ctgatgccgc tggcgattca ggttcatcat
      841 gccgtttgtg atggcttcca tgtcggcaga atgcttaatg aattacaaca gtactgcgat
      901 gagtggcagg gcggggcgta atttttttaa ggcagttatt ggtgccctta aacgcctggt
      961 tgctacgcct gaataagtga taataagcgg atgaatggca gaaattcgaa agcaaattcg
     1021 acccggtcgt cggttcaggg cagggtcgtt aaatagccgc ttatgtctat tgctggttta
     1081 ccggtttatt gactaccgga agcagtgtga ccgtgtgctt ctcaaatgcc tgaggccagt
     1141 ttgctcaggc tctccccgtg gaggtaataa ttgacgatat gatcatttat tctgcctccc
     1201 agagcctgat aaaaacggtt agcgccgggg ttggattttt cagcgttcca gctaaggcta
     1261 aggcattcct gttcaagcgc aagccgggct ataaagcgca ttatcgcttt acccgtgccc
     1321 ttatttcgat cgcactgaga aacatacagc tctttaatat gcagctgacc gctgtatcgg
     1381 ggcgagggat aaagaatatt gcaacatgcc aggccagtaa tgttattgcc gcagcgcgct
     1441 ctgatcacca gggtaccgga aagccggttg aataactttt tacagagata atccttcatc
     1501 aacgcttcct gaatgatacc ttcgccataa taggggtcgt ctcagaaaac ggaaaataaa
     1561 gcacgctaag ccggttgcag aggccgtagc ggcctgaact tccccgcgcc gatcttggcg
     1621 ctgctgcgcc ataggtaatc accggtcagg ttgatgtgct cccagccgag tggcgacagg
     1681 tactgcaata gcgagtcatc gacggcatga ccattgccgc gcaacgcatg cgccgcacgc
     1741 tccaggtaga ccgtgttcca cagcacgatg gccgccgtca ccaggttgag gccgctggcc
     1801 cggtagcgct gctgctcgaa actgcggtca cggatttcac caaggcggtt gaagaacacg
     1861 gcacgggcca gcgcattgcg cgcctcgccc ttgttcagcc cggcatgcac gcggcggcgt
     1921 agctcgacgc tttgcagcca gtcgaggatg aacagcgtgc gctcgatgcg gcccaactcg
     1981 cgcagcgcga cggccaagcc gttctggcgc gggtagctgc cgagtttcct gagcatcagc
     2041 gaggccgtca ccgtgccctg cttgatcgag gtggccagcc gcaggatttc gtcccaatgg
     2101 gcgcggacgt gcttgatgtt gagcgtgccg ccgatcatcg gcttgagcgc gtcataggcg
     2161 gcatcgccct tcgggatgta gagcttggtg tcgcccaggt cgcggatgcg cggcgcgaag
     2221 cggaagccca agaggtgcat cagggcgaag acgtgatcgg tgaagcccgc cgtgtcggtg
     2281 tagtgctcct cgatccgcag gtcggattcg tggtacagca ggccgtcgag cacgtaggtt
     2341 gagtcgcgca ggccgacatt gaccaccttg gtgtggaatg gcgcgtattg gtcggagatg
     2401 tgggtgtaga aagtccgtcc tgggctgctg ccatattttg ggttgatgtg ccccgtgctc
     2461 tttgccttgc tagcggttcg gaaattctgt ccgtccgatg atgatgtggt gccatcgccc
     2521 cagtgcccgg caaagggatg ccgaaactga gcgttgacca gttcagccaa cgctgtcgag
     2581 tacgtttcgt cgcgggtatg ccaggcttgc agccaagcga gcttcgcgta ggtcgtgccg
     2641 gggcaggact cggccatctt ggtcaggccc aggttgatcg cgtcggccag gatcgtggtc
     2701 aacaacaggt tcttgtcctt ggccagatcg cccgatttca agtgcgtgaa gtgccgggtg
     2761 aagcccgtcc actcatcgac ttcgagcagc agttcggtga tcttgacgtg cggcaggacc
     2821 atggctgtct ggtctatcag cgcctgcgcg g
//
LOCUS       DADXDL010000356         2749 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.222, whole genome shotgun sequence.
ACCESSION   DADXDL010000356 DADXDL010000000
VERSION     DADXDL010000356.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2749
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.222"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..362)
                     /locus_tag="IRB70_005129"
     CDS             complement(<1..362)
                     /locus_tag="IRB70_005129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_416498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HBC0634891.1"
                     /translation="MFVIWSHGTGFIMSHQLTFADSEFSSKRRQTRKEIFLSRMEQIL
                     PWQNMVEVIEPFYPKAGNGRRPYPLETMLRIHCMQHWYNLSDGAMEDALYEIASMRLF
                     ARLSLDSALPDRTTIMNFR"
     gene            561..1373
                     /locus_tag="IRB70_005130"
     CDS             561..1373
                     /locus_tag="IRB70_005130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032492661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="subclass B1 metallo-beta-lactamase NDM-5"
                     /protein_id="HBC0634892.1"
                     /translation="MELPNIMHPVAKLSTALAAALMLSGCMPGEIRPTIGQQMETGDQ
                     RFGDLVFRQLAPNVWQHTSYLDMPGFGAVASNGLIVRDGGRVLLVDTAWTDDQTAQIL
                     NWIKQEINLPVALAVVTHAHQDKMGGMDALHAAGIATYANALSNQLAPQEGLVAAQHS
                     LTFAANGWVEPATAPNFGPLKVFYPGPGHTSDNITVGIDGTDIAFGGCLIKDSKAKSL
                     GNLGDADTEHYAASARAFGAAFPKASMIVMSHSAPDSRAAITHTARMADKLR"
     gene            1377..1742
                     /gene="ble"
                     /locus_tag="IRB70_005131"
     CDS             1377..1742
                     /gene="ble"
                     /locus_tag="IRB70_005131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bleomycin binding protein Ble-MBL"
                     /protein_id="HBC0634893.1"
                     /translation="MADHVTPNLPSRDFDVTEAFYAKLGFATSWKDRGWMILQRGGLQ
                     LEFFPYPDLDPATSSFGCCLRLDDLDAMVALVNAAGAEEKSTGWPRFKAPQLEASGLR
                     IGYLIDPDCTLVRLIQNPD"
     gene            1747..2385
                     /locus_tag="IRB70_005132"
     CDS             1747..2385
                     /locus_tag="IRB70_005132"
                     /EC_number="5.3.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylanthranilate isomerase"
                     /protein_id="HBC0634894.1"
                     /translation="MPAKIKICGISTPEALDATIAARADYAGLVFYPASPRAVTSNVA
                     GALTSRAAGQIAMVGLFVDADDAVIADALVAAKLNALQLHGSESPERVAQLRARFGKP
                     VWKALPVASASDVARAAAYAGAADLILFDAKTPKGALPGGMGLAFDWSLLAGYRGALP
                     WGLAGGLNPTNVAEAIARTGAPLVDTSSGVESAPGVKDTDKITNFAFAVRLA"
     gene            complement(2396..>2749)
                     /locus_tag="IRB70_005133"
     CDS             complement(2396..>2749)
                     /locus_tag="IRB70_005133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004201169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634895.1"
                     /translation="DVNKSIYLEGKSPQPHRWEPAEGWFAKYDHPLWKRYADLAAGAG
                     HGGMDWFVIHAFVEALKAKAPMPIDIYDALAWSAITPLSEQSIAEGNRTLDFPDFTRG
                     QWRTRKPIFALNDAY"
BASE COUNT          534 a          809 c          831 g          575 t
ORIGIN      
        1 cggaaattca tgatggtggt gcggtcaggc aaggcgctat ccagggataa ccgggcaaac
       61 agacgcatgg aggcgatttc gtacagagca tcttccatcg cgccatcgct caggttgtac
      121 caatgctgca tgcagtgaat gcgtagcatg gtttccagcg gataaggtcg ccggccatta
      181 ccagccttgg ggtaaaacgg ctcgatgact tccaccatgt tttgccatgg cagaatctgc
      241 tccatgcggg acaagaaaat ctcttttctg gtctgacggc gcttactgct gaattcactg
      301 tcggcgaagg taagttgatg actcatgatg aaccctgttc catggctcca gatgacaaac
      361 atgatctcat atcagggact tgttcgcacc ttccttagag aaatttgctc agcttgttga
      421 ttatcatatg gcttttgaaa ctgtcgcacc tcatgtttga attcgcccca tatttttgct
      481 acagtgaacc aaattaagat catctattta ctaggcctcg catttgcggg gtttttaatg
      541 ctgaataaaa ggaaaacttg atggaattgc ccaatattat gcacccggtc gcgaagctga
      601 gcaccgcatt agccgctgca ttgatgctga gcgggtgcat gcccggtgaa atccgcccga
      661 cgattggcca gcaaatggaa actggcgacc aacggtttgg cgatctggtt ttccgccagc
      721 tcgcaccgaa tgtctggcag cacacttcct atctcgacat gccgggtttc ggggcagtcg
      781 cttccaacgg tttgatcgtc agggatggcg gccgcgtgct gttggtcgat accgcctgga
      841 ccgatgacca gaccgcccag atcctcaact ggatcaagca ggagatcaac ctgccggtcg
      901 cgctggcggt ggtgactcac gcgcatcagg acaagatggg cggtatggac gcgctgcatg
      961 cggcggggat tgcgacttat gccaatgcgt tgtcgaacca gcttgccccg caagaggggc
     1021 tggttgcggc gcaacacagc ctgactttcg ccgccaatgg ctgggtcgaa ccagcaaccg
     1081 cgcccaactt tggcccgctc aaggtatttt accccggccc cggccacacc agtgacaata
     1141 tcaccgttgg gatcgacggc accgacatcg cttttggtgg ctgcctgatc aaggacagca
     1201 aggccaagtc gctcggcaat ctcggtgatg ccgacactga gcactacgcc gcgtcagcgc
     1261 gcgcgtttgg tgcggcgttc cccaaggcca gcatgatcgt gatgagccat tccgcccccg
     1321 atagccgcgc cgcaatcact catacggccc gcatggccga caagctgcgc tgagccatgg
     1381 ctgaccacgt cacccccaat ctgccatcgc gcgatttcga tgtgacagag gcgttttatg
     1441 cgaagctggg ctttgcgacg agttggaagg atcgcggctg gatgatcctg cagcgcggcg
     1501 gtttgcagct cgaattcttc ccctatcctg acctcgaccc agctacgagc tcgttcggct
     1561 gttgcctgcg gttggatgat ctcgatgcca tggtggcatt ggtgaacgcg gcgggagccg
     1621 aggaaaaaag caccggctgg ccgcgcttca aagctccgca actggaggcg agcggcctga
     1681 ggatcggcta cctgatcgat cccgactgca cgctggtgcg gctgatccag aaccccgact
     1741 gaccgcatgc ccgcgaaaat caagatttgc gggatcagca cacccgaggc gctcgatgcg
     1801 accatcgcgg cgcgggcgga ctatgccggg ttggtgttct atccagcgtc gccccgtgcg
     1861 gttacgtcga atgtcgcggg cgctttgaca tcgcgcgcag ctggccagat cgccatggtc
     1921 ggtttgttcg tcgatgcgga tgatgctgtc atcgccgacg cactggtggc agccaagctg
     1981 aacgcgctgc agctgcacgg ttcggaatcg cccgaacgcg tggcccagtt gcgcgcgcgg
     2041 tttggcaagc cggtgtggaa ggcgctgccc gtcgccagcg ccagcgatgt cgcacgcgcc
     2101 gcagcctatg ccggggcggc ggacttgatc ttgttcgacg ccaagacccc caaaggcgcg
     2161 ctgcccggcg gcatggggtt ggcgttcgac tggtcgctgc tggccggata tcgcggtgcc
     2221 ttgccgtggg ggctggcagg cgggctaaat ccgacgaatg ttgccgaggc gattgcgcgc
     2281 accggagcgc cgctggtcga tacctccagc ggcgtcgaaa gcgcgccggg cgtcaaggat
     2341 accgacaaga ttaccaattt cgcctttgcg gtgcgcttgg cctaaatcgc gtcgatcaat
     2401 aggcgtcgtt cagcgcaaag atcggcttgc gggtgcgcca ctgccctcgg gtgaagtcgg
     2461 gaaaatctaa cgtgcgattg ccctcagcaa tcgattgttc cgacagaggc gtgatcgcgc
     2521 tccaggccag cgcgtcgtaa atgtcgattg gcatcggggc cttggccttc agcgcctcga
     2581 caaaagcgtg gatcacgaac cagtccatcc cgccatgccc ggcccctgcc gccagatcgg
     2641 cgtagcgttt ccatagcggg tgatcgtatt tcgcaaacca gccctcggca ggctcccagc
     2701 ggtgcggctg tgggctcttg ccctccagat agatcgactt gttgacgtc
//
LOCUS       DADXDL010000357         2616 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.228, whole genome shotgun sequence.
ACCESSION   DADXDL010000357 DADXDL010000000
VERSION     DADXDL010000357.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2616
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.228"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            15..701
                     /locus_tag="IRB70_005134"
     CDS             15..701
                     /locus_tag="IRB70_005134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001284954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBC0634896.1"
                     /translation="MANLIRKEVTFESSIAAIGAAMSDISRVKILSALMDGRAWTATE
                     LSSVANISASTASSHLSKLLDCQLITVVAQGKHRYFRLAGKDIAELMESMMGISLNHG
                     VHAKVSTPVHLRKARTCYDHLAGEVAVKIYDSLCQQQWITENGSMITLSGIQYFHEMG
                     IDVPSKHSRKICCACLDWSERRFHLGGYVGAALFSLYESKGWLTRHLGYREVTITEKG
                     YAAFKTHFHI"
     gene            complement(679..1302)
                     /gene="tetR(B)"
                     /locus_tag="IRB70_005135"
     CDS             complement(679..1302)
                     /gene="tetR(B)"
                     /locus_tag="IRB70_005135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000088605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance transcriptional
                     repressor TetR(B)"
                     /protein_id="HBC0634897.1"
                     /translation="MSRLDKSKVINSALELLNEVGIEGLTTRKLAQKLGVEQPTLYWH
                     VKNKRALLDALAIEMLDRHHTHFCPLEGESWQDFLRNNAKSFRCALLSHRDGAKVHLG
                     TRPTEKQYETLENQLAFLCQQGFSLENALYALSAVGHFTLGCVLEDQEHQVAKEERET
                     PTTDSMPPLLRQAIELFDHQGAEPAFLFGLELIICGLEKQLKCESGS"
     gene            1384..2589
                     /gene="tet(B)"
                     /locus_tag="IRB70_005136"
     CDS             1384..2589
                     /gene="tet(B)"
                     /locus_tag="IRB70_005136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001089064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline efflux MFS transporter Tet(B)"
                     /protein_id="HBC0634898.1"
                     /translation="MNSSTKIALVITLLDAMGIGLIMPVLPTLLREFIASEDIANHFG
                     VLLALYALMQVIFAPWLGKMSDRFGRRPVLLLSLIGASLDYLLLAFSSALWMLYLGRL
                     LSGITGATGAVAASVIADTTSASQRVKWFGWLGASFGLGLIAGPIIGGFAGEISPHSP
                     FFIAALLNIVAFLVVMFWFRETKNTRDNTDTEVGVETQSNSVYITLFKTMPILLIIYF
                     SAQLIGQIPATVWVLFTENRFGWNSMMVGFSLAGLGLLHSVFQAFVAGRIATKWGEKT
                     AVLLGFIADSSAFAFLAFISEGWLVFPVLILLAGGGIALPALQGVMSIQTKSHQQGAL
                     QGLLVSLTNATGVIGPLLFAVIYNHSLPIWDGWIWIIGLAFYCIIILLSMTFMLTPQA
                     QGSKQETSA"
BASE COUNT          665 a          506 c          586 g          859 t
ORIGIN      
        1 aaagtgaact tgcgatggct aatttaatac gaaaagaggt tacctttgag tcctcaatag
       61 ccgcgatagg ggcggctatg tctgacattt cacgagttaa aatactcagt gctttgatgg
      121 atgggcgagc ttggacggcc actgagctaa gttctgtggc gaatatatca gcttcaacgg
      181 cgagcagtca tttatctaaa ttattagatt gccagctaat cacagtagta gctcaaggca
      241 agcatcgtta ttttcggcta gcaggaaaag atattgctga attgatggaa agtatgatgg
      301 ggatctcctt aaaccatggc gtacatgcca aagtttccac gccagtgcat ttacgaaaag
      361 cacgtacttg ctatgatcat ttagctggcg aagttgccgt taagatctat gattcccttt
      421 gtcaacagca atggatcact gaaaatggtt caatgatcac attaagtggt attcaatatt
      481 ttcatgaaat gggaattgac gttccttcca aacattcacg taaaatctgt tgtgcgtgtt
      541 tagattggag tgaacgccgt ttccatttag gtgggtacgt tggagccgca ttattttcgc
      601 tttatgaatc taaagggtgg ttaactcgac atcttggtta ccgtgaagtt accatcacgg
      661 aaaaaggtta tgctgctttt aagacccact ttcacattta agttgttttt ctaatccgca
      721 tatgatcaat tcaaggccga ataagaaggc tggctctgca ccttggtgat caaataattc
      781 gatagcttgt cgtaataatg gcggcatact atcagtagta ggtgtttccc tttcttcttt
      841 agcgacttga tgctcttgat cttccaatac gcaacctaaa gtaaaatgcc ccacagcgct
      901 gagtgcatat aatgcattct ctagtgaaaa accttgttgg cataaaaagg ctaattgatt
      961 ttcgagagtt tcatactgtt tttctgtagg ccgtgtacct aaatgtactt ttgctccatc
     1021 gcgatgactt agtaaagcac atctaaaact tttagcgtta ttacgtaaaa aatcttgcca
     1081 gctttcccct tctaaagggc aaaagtgagt atggtgccta tctaacatct caatggctaa
     1141 ggcgtcgagc aaagcccgct tattttttac atgccaatac aatgtaggct gctctacacc
     1201 tagcttctgg gcgagtttac gggttgttaa accttcgatt ccgacctcat taagcagctc
     1261 taatgcgctg ttaatcactt tacttttatc taatctagac atcattaatt cctaattttt
     1321 gttgacactc tatcattgat agagttattt taccactccc tatcagtgat agagaaaagt
     1381 gaaatgaata gttcgacaaa gatcgcattg gtaattacgt tactcgatgc catggggatt
     1441 ggccttatca tgccagtctt gccaacgtta ttacgtgaat ttattgcttc ggaagatatc
     1501 gctaaccact ttggcgtatt gcttgcactt tatgcgttaa tgcaggttat ctttgctcct
     1561 tggcttggaa aaatgtctga ccgatttggt cggcgcccag tgctgttgtt gtcattaata
     1621 ggcgcatcgc tggattactt attgctggct ttttcaagtg cgctttggat gctgtattta
     1681 ggccgtttgc tttcagggat cacaggagct actggggctg tcgcggcatc ggtcattgcc
     1741 gataccacct cagcttctca acgcgtgaag tggttcggtt ggttaggggc aagttttggg
     1801 cttggtttaa tagcggggcc tattattggt ggttttgcag gagagatttc accgcatagt
     1861 ccctttttta tcgctgcgtt gctaaatatt gtcgctttcc ttgtggttat gttttggttc
     1921 cgtgaaacca aaaatacacg tgataataca gataccgaag taggggttga gacgcaatcg
     1981 aattcggtat acatcacttt atttaaaacg atgcccattt tgttgattat ttatttttca
     2041 gcgcaattga taggccaaat tcccgcaacg gtgtgggtgc tatttaccga aaatcgtttt
     2101 ggatggaata gcatgatggt tggcttttca ttagcgggtc ttggtctttt acactcagta
     2161 ttccaagcct ttgtggcagg aagaatagcc actaaatggg gcgaaaaaac ggcagtactg
     2221 ctcggattta ttgcagatag tagtgcattt gcctttttag cgtttatatc tgaaggttgg
     2281 ttagttttcc ctgttttaat tttattggct ggtggtggga tcgctttacc tgcattacag
     2341 ggagtgatgt ctatccaaac aaagagtcat cagcaaggtg ctttacaggg attattggtg
     2401 agccttacca atgcaaccgg tgttattggc ccattactgt ttgctgttat ttataatcat
     2461 tcactaccaa tttgggatgg ctggatttgg attattggtt tagcgtttta ctgtattatt
     2521 atcctgctat cgatgacctt catgttaacc cctcaagctc aggggagtaa acaggagaca
     2581 agtgcttagt tatttcgtca ccaaatgatg ttattc
//
LOCUS       DADXDL010000358         2265 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.239, whole genome shotgun sequence.
ACCESSION   DADXDL010000358 DADXDL010000000
VERSION     DADXDL010000358.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2265
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.239"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            131..685
                     /locus_tag="IRB70_005137"
     CDS             131..685
                     /locus_tag="IRB70_005137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003159191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fluoroquinolone-acetylating aminoglycoside
                     6'-N-acetyltransferase AAC(6')-Ib-cr5"
                     /protein_id="HBC0634899.1"
                     /translation="MTNSNDSVTLRLMTEHDLAMLYEWLNRSHIVEWWGGEEARPTLA
                     DVQEQYLPSVLAQESVTPYIAMLNGEPIGYAQSYVALGSGDGRWEEETDPGVRGIDQL
                     LANASQLGKGLGTKLVRALVELLFNDPEVTKIQTDPSPSNLRAIRCYEKAGFERQGTV
                     TTPYGPAVYMVQTRQAFERTRSDA"
     gene            816..1646
                     /locus_tag="IRB70_005138"
     CDS             816..1646
                     /locus_tag="IRB70_005138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxacillin-hydrolyzing class D beta-lactamase
                     OXA-1"
                     /protein_id="HBC0634900.1"
                     /translation="MKNTIHINFAIFLIIANIIYSSASASTDISTVASPLFEGTEGCF
                     LLYDASTNAEIAQFNKAKCATQMAPDSTFKIALSLMAFDAEIIDQKTIFKWDKTPKGM
                     EIWNSNHTPKTWMQFSVVWVSQEITQKIGLNKIKNYLKDFDYGNQDFSGDKERNNGLT
                     EAWLESSLKISPEEQIQFLRKIINHNLPVKNSAIENTIENMYLQDLDNSTKLYGKTGA
                     GFTANRTLQNGWFEGFIISKSGHKYVFVSALTGNLGSNLTSSIKAKKNAITILNTLNL
                     "
     gene            1784..>2265
                     /locus_tag="IRB70_005139"
     CDS             1784..>2265
                     /locus_tag="IRB70_005139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002075262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CatB-related O-acetyltransferase"
                     /protein_id="HBC0634901.1"
                     /translation="MTNYFDSPFKGKLLSEQVKNPNIKVGRYSYYSGYYHGHSFDDCA
                     RYLFPDRDDVDKLIIGSFCSIGSGASFIMAGNQGHRYDWASSFPFFYMQEEPAFSSAL
                     DAFQKAGNTVIGNDVWIGSEAMVMPGIKIGHGAVIGSRSLVTKDVGHCCKVSDEAAFC
                     L"
BASE COUNT          697 a          515 c          513 g          540 t
ORIGIN      
        1 gacaaaaggc tgcctcatcg ctaactttgc aacagtgcct ttaagcgtgc ataataagcc
       61 ctacacaaat tgggagttag acatcatgag caacgcaaaa acaaagttag gcatcacaaa
      121 gtacagcatc gtgaccaaca gcaacgattc cgtcacactg cgcctcatga ctgagcatga
      181 ccttgcgatg ctctatgagt ggctaaatcg atctcatatc gtcgagtggt ggggcggaga
      241 agaagcacgc ccgacacttg ctgacgtaca ggaacagtac ttgccaagcg ttttagcgca
      301 agagtccgtc actccataca ttgcaatgct gaatggagag ccgattgggt atgcccagtc
      361 gtacgttgct cttggaagcg gggacggacg gtgggaagaa gaaaccgatc caggagtacg
      421 cggaatagac cagttactgg cgaatgcatc acaactgggc aaaggcttgg gaaccaagct
      481 ggttcgagct ctggttgagt tgctgttcaa tgatcccgag gtcaccaaga tccaaacgga
      541 cccgtcgccg agcaacttgc gagcgatccg atgctacgag aaagcggggt ttgagaggca
      601 aggtaccgta accaccccat atggtccagc cgtgtacatg gttcaaacac gccaggcatt
      661 cgagcgaaca cgcagtgatg cctaaccctt ccatcgaggg ggacgtccaa gggctggcgc
      721 ccttggccgc ccctcatgtc aaacgttggg cgaacccgga gcctcattaa ttgttagccg
      781 ttaaaattaa gccctttacc aaaccaatac ttattatgaa aaacacaata catatcaact
      841 tcgctatttt tttaataatt gcaaatatta tctacagcag cgccagtgca tcaacagata
      901 tctctactgt tgcatctcca ttatttgaag gaactgaagg ttgtttttta ctttacgatg
      961 catccacaaa cgctgaaatt gctcaattca ataaagcaaa gtgtgcaacg caaatggcac
     1021 cagattcaac tttcaagatc gcattatcac ttatggcatt tgatgcggaa ataatagatc
     1081 agaaaaccat attcaaatgg gataaaaccc ccaaaggaat ggagatctgg aacagcaatc
     1141 atacaccaaa gacgtggatg caattttctg ttgtttgggt ttcgcaagaa ataacccaaa
     1201 aaattggatt aaataaaatc aagaattatc tcaaagattt tgattatgga aatcaagact
     1261 tctctggaga taaagaaaga aacaacggat taacagaagc atggctcgaa agtagcttaa
     1321 aaatttcacc agaagaacaa attcaattcc tgcgtaaaat tattaatcac aatctcccag
     1381 ttaaaaactc agccatagaa aacaccatag agaacatgta tctacaagat ctggataata
     1441 gtacaaaact gtatgggaaa actggtgcag gattcacagc aaatagaacc ttacaaaacg
     1501 gatggtttga agggtttatt ataagcaaat caggacataa atatgttttt gtgtccgcac
     1561 ttacaggaaa cttggggtcg aatttaacat caagcataaa agccaagaaa aatgcgatca
     1621 ccattctaaa cacactaaat ttataaaaaa tctaatggca aaatcgccca acccttcaat
     1681 caagtcggga cggccaaaag caagcttttg gctcccctcg ctggcgctcg gcgcccctta
     1741 tttcaaacgt tagacggcaa agtcacagac cgcgggatct cttatgacca actactttga
     1801 tagccccttc aaaggcaagc tgctttctga gcaagtgaag aaccccaata tcaaagttgg
     1861 gcggtacagc tattactctg gctactatca tgggcactca ttcgatgact gcgcacggta
     1921 tctgtttccg gaccgtgatg acgttgataa gttgatcatc ggtagtttct gctctatcgg
     1981 gagtggggct tcctttatca tggctggcaa tcaggggcat cggtacgact gggcatcatc
     2041 tttcccgttc ttttatatgc aggaagaacc tgcattctca agcgcactcg atgccttcca
     2101 aaaagcaggt aatactgtca ttggcaatga cgtttggatc ggctctgagg caatggtcat
     2161 gcccggaatc aagatcgggc acggtgcggt gataggcagc cgctcgttgg tgacaaaaga
     2221 tgtggggcac tgttgcaaag ttagcgatga ggcagccttt tgtct
//
LOCUS       DADXDL010000359         2261 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.240, whole genome shotgun sequence.
ACCESSION   DADXDL010000359 DADXDL010000000
VERSION     DADXDL010000359.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 2261)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2261)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2261
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.240"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..200
                     /locus_tag="IRB70_005140"
     CDS             <1..200
                     /locus_tag="IRB70_005140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="QacE family quaternary ammonium compound efflux
                     SMR transporter"
                     /protein_id="HBC0634902.1"
                     /translation="LKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLI
                     IAAFLLARSPSWKSLRRPTPW"
     gene            194..1033
                     /gene="sul1"
                     /locus_tag="IRB70_005141"
     CDS             194..1033
                     /gene="sul1"
                     /locus_tag="IRB70_005141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000259031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfonamide-resistant dihydropteroate synthase
                     Sul1"
                     /protein_id="HBC0634903.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     GPAASHPDARPVSPADEIRRIAPLLDALSDQMHRVSIDSFQPETQRYALKRGVGYLND
                     IQGFPDPALYPDIAEADCRLVVMHSAQRDGIATRTGHLRPEDALDEIVRFFEARVSAL
                     RRSGVAADRLILDPGMGFFLSPAPETSLHVLSNLQKLKSALGLPLLVSVSRKSFLGAT
                     VGLPVKDLGPASLAAELHAIGNGADYVRTHAPGDLRSAITFSETLAKFRSRDARDRGL
                     DHA"
     gene            1161..1364
                     /locus_tag="IRB70_005142"
     CDS             1161..1364
                     /locus_tag="IRB70_005142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000376616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBC0634904.1"
                     /translation="MDSEEPPNVRVACSGDIDEVVRLMHDAAAWMSAKGTPAWDVARI
                     DRTFAETFVLRSELLGIASENGK"
     gene            1520..>2261
                     /locus_tag="IRB70_005143"
     CDS             1520..>2261
                     /locus_tag="IRB70_005143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004896675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromate transporter"
                     /protein_id="HBC0634905.1"
                     /translation="MTNNPTDDSRPWSVFLIFLRLGLTSFGGPIAHLGYFRAEFVTRR
                     RWLSERSYADLVALCQFLPGPASSQVGIAVGLSRAGYSGALAAWAGFTLPSAIALILF
                     ALGISSYGDYVSQGALHGLKVVAVAVVAQAVWGMARNLCTDGLRVTIMAIATCVVLLV
                     PSAWGQVGVIAIAGIAGRLLFKPAKVVEHDPLPITVSHRAGVLWLSLFFVLLIGLPVL
                     AELMPSQTMAMVDSFYRVGSLVFGGGHVV"
BASE COUNT          407 a          640 c          686 g          528 t
ORIGIN      
        1 ttctgaaatc catccctgtc ggtgttgctt atgcagtctg gtcgggactc ggcgtcgtca
       61 taattacagc cattgcctgg ttgcttcatg ggcaaaagct tgatgcgtgg ggctttgtag
      121 gtatggggct cataattgct gcctttttgc tcgcccgatc cccatcgtgg aagtcgctgc
      181 ggaggccgac gccatggtga cggtgttcgg cattctgaat ctcaccgagg actccttctt
      241 cgatgagagc cggcggctag accccgccgg cgctgtcacc gcggcgatcg aaatgctgcg
      301 agtcggatca gacgtcgtgg atgtcggacc ggccgccagc catccggacg cgaggcctgt
      361 atcgccggcc gatgagatca gacgtattgc gccgctctta gacgccctgt ccgatcagat
      421 gcaccgtgtt tcaatcgaca gcttccaacc ggaaacccag cgctatgcgc tcaagcgcgg
      481 cgtgggctac ctgaacgata tccaaggatt tcctgaccct gcgctctatc ccgatattgc
      541 tgaggcggac tgcaggctgg tggttatgca ctcagcgcag cgggatggca tcgccacccg
      601 caccggtcac cttcgacccg aagacgcgct cgacgagatt gtgcggttct tcgaggcgcg
      661 ggtttccgcc ttgcgacgga gcggggtcgc tgccgaccgg ctcatcctcg atccggggat
      721 gggatttttc ttgagccccg caccggaaac atcgctgcac gtgctgtcga accttcaaaa
      781 gctgaagtcg gcgttggggc ttccgctatt ggtctcggtg tcgcggaaat ccttcttggg
      841 cgccaccgtt ggccttcctg taaaggatct gggtccagcg agccttgcgg cggaacttca
      901 cgcgatcggc aatggcgctg actacgtccg cacccacgcg cctggagatc tgcgaagcgc
      961 aatcaccttc tcggaaaccc tcgcgaaatt tcgcagtcgc gacgccagag accgagggtt
     1021 agatcatgcc tagcattcac cttccggccg cccgctagcg gaccctggtc aggttccgcg
     1081 aaggtgggcg cagacatgct gggctcgtca ggatcaaact gcactatgag gcggcggttc
     1141 ataccgcgcc aggggagcga atggacagcg aggagcctcc gaacgttcgg gtcgcctgct
     1201 cgggtgatat cgacgaggtt gtgcggctga tgcacgacgc tgcggcgtgg atgtccgcca
     1261 agggaacgcc cgcctgggac gtcgcgcgga tcgaccggac attcgcggag accttcgtcc
     1321 tgagatccga gctcctaggg atcgcctcag aaaacggaaa ataaagcacg ctaagccgta
     1381 agtaagcgtg ctcctgtgaa agccacagct aaaactgcgt agtacacata gaggtatttt
     1441 tttctagatt tatatcgaat ttcgttatcg aatttcgctt attattgatc aactcgttgc
     1501 agatcatgaa ggcgaaagta tgacgaataa ccctaccgat gacagcagac catggtcggt
     1561 ctttcttatt tttctgcggc ttggattgac atcttttggc ggccccattg cgcacttggg
     1621 ctacttccgc gccgaatttg tcacacggcg gcgctggctc tccgaacgga gctatgctga
     1681 cttggtcgcg ctttgtcagt tcttgccagg gcctgcaagc agccaggtcg gcatagcggt
     1741 aggactgtct cgggctggat acagcggggc gctggctgct tgggctggct tcacgctgcc
     1801 gtctgccata gccttgatcc tttttgcgct cggcatctcc agctatggcg attacgtctc
     1861 gcagggcgcg ttgcatggct taaaagtggt ggctgtggcc gtggtcgctc aagcagtatg
     1921 gggcatggcg cgtaacctat gcacggatgg gctgcgagtc accatcatgg caattgctac
     1981 ctgcgtcgtt ttacttgtgc cgtccgcgtg gggacaggtt ggcgtgattg ctatcgcagg
     2041 catcgcaggc cggttattgt tcaagccagc gaaagttgtt gagcatgacc ccctacctat
     2101 cacggtcagt caccgggccg gcgtgctttg gctctcgctg ttctttgtct tgctgattgg
     2161 cctgccggtg ttggccgaac tgatgccaag tcaaaccatg gcaatggtgg attccttcta
     2221 tcgtgtcgga tcactggtgt tcggcggtgg tcacgttgtg c
//
LOCUS       DADXDL010000360         1830 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.251, whole genome shotgun sequence.
ACCESSION   DADXDL010000360 DADXDL010000000
VERSION     DADXDL010000360.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1830)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1830)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1830
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.251"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            83..943
                     /gene="aac(3)-IIe"
                     /locus_tag="IRB70_005144"
     CDS             83..943
                     /gene="aac(3)-IIe"
                     /locus_tag="IRB70_005144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000557454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(3)-IIe"
                     /protein_id="HBC0634906.1"
                     /translation="MHTRKAITEAIRKLGVQTGDLLMVHASLKAIGPVEGGAETVVAA
                     LRSAVGPTGTVMGYASWDRSPYEETLNGARLDDKARRTWPPFDPATAGTYRGFGLLNQ
                     FLVQAPGARRSAHPDASMVAVGPLAETLTEPHELGHALGEGSPVERFVRLGGKALLLG
                     APLNSVTALHYAEAVADIPNKRWVTYEMPMLGRNGEVAWKTASEYDSNGILDCFAIEG
                     KPDAVETIANAYVKLGRHREGVVGFAQCYLFDAQDIVTFGVTYLEKHFGATPIVPAHE
                     AAQRSCEPSG"
     gene            956..1498
                     /locus_tag="IRB70_005145"
     CDS             956..1498
                     /locus_tag="IRB70_005145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBC0634907.1"
                     /translation="MIIWINGPFGAGKTTLAERLRDRRPKSLIFDPEEIGFVVKETVP
                     IPASGDYQDLPLWRGLTIAAVSEIRRNYSQDIIIPMTLVHPDYLTEILDGLRQIDDQL
                     LHIFLMLNEDLLRHRISNQTMHPDPNRNAEIREWRLANVARCLAARERLPSTTRVLDS
                     GAHTSDELAAMVLDRLDQRT"
     gene            1569..>1830
                     /locus_tag="IRB70_005146"
     CDS             1569..>1830
                     /locus_tag="IRB70_005146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634908.1"
                     /translation="MPGTGETMTRRPRRNHSPAFKAKVALAAIRGEQTLVELSQQFDV
                     HANQIKQWKDQLLEGATGVFGDETKAEPSGPTIDVKTLHAKIG"
BASE COUNT          409 a          498 c          558 g          365 t
ORIGIN      
        1 atgataagtt tatcaccacc gactatttgc aacagtgcct ctcgataggt atagtgtttt
       61 gcagtttaga ggagatatcg cgatgcatac gcggaaggca ataacggagg caattcgaaa
      121 attaggagtc caaaccggtg acctgttgat ggtgcatgcc tcacttaaag cgattggtcc
      181 ggtcgaagga ggagcggaga cggtcgttgc cgcgttacgc tccgcggttg ggccgactgg
      241 cactgtgatg ggatacgcgt cgtgggaccg atcaccctac gaggagactc tgaatggcgc
      301 tcggttggat gacaaagccc gccgtacctg gccgccgttc gatcccgcaa cggccgggac
      361 ttaccgtggg ttcggcctgc tgaatcaatt tctggttcaa gcccccggcg cgcggcgcag
      421 cgcgcacccc gatgcatcga tggtcgcggt tggtccgcta gctgaaacgc tgacggagcc
      481 tcacgaactc ggtcacgcct tgggggaagg gtcgcccgtc gagcggttcg tccgccttgg
      541 cgggaaggcc ctgctgttgg gtgcgccgct aaactccgtt accgcattgc actacgccga
      601 ggcggttgcg gatatcccca acaaacgatg ggtgacgtat gagatgccga tgcttggaag
      661 aaacggtgaa gtcgcctgga aaacggcatc agaatacgat tcaaacggca ttctcgattg
      721 ctttgctatc gaaggaaagc cggatgcggt cgaaactata gcaaatgctt acgtgaagct
      781 cggtcgccat cgagaaggtg tcgtgggctt tgctcagtgc tacctgttcg acgcgcagga
      841 catcgtgacg ttcggcgtca cctatcttga gaagcacttc ggagccactc cgatcgtgcc
      901 agcacacgaa gccgcccagc gctcttgcga gccttccggt tagaggccgt cgacaatgat
      961 aatctggatc aacggacctt tcggcgccgg aaagacgact ctcgctgagc ggctgcgcga
     1021 tcggcgtccg aaatcgctga tctttgaccc tgaggaaatc gggttcgtgg tgaaagaaac
     1081 ggtccccata ccagcgagcg gagactatca ggatctcccc ttgtggaggg gacttacgat
     1141 cgctgcggtc agcgagattc gcaggaatta ctcgcaggac atcatcatcc caatgacgct
     1201 cgtgcacccg gactatctga ctgagatact cgacgggtta aggcagatcg acgatcagct
     1261 gctgcacatc tttctgatgc ttaacgagga cctattgcgt caccggatct cgaaccagac
     1321 catgcatcct gacccgaatc ggaatgcgga gattcgagag tggcgattag cgaatgtcgc
     1381 ccgatgcttg gccgcaaggg aacggcttcc gtccacaacc cgtgttctcg atagtggtgc
     1441 acacaccagc gatgaacttg cagcgatggt gctcgacaga ctcgatcagc gcacctgatc
     1501 gccttagagc tggctcggga aatctgcaca gcggggataa gtggagtttc tgcctgactt
     1561 cggcttagat gccgggaaca ggagagacca tgacgagacg accgcgccgg aaccatagcc
     1621 cggctttcaa ggcgaaggtg gcacttgccg ccatccgagg tgagcagacg ctggtggagt
     1681 tgtcccagca gttcgatgtg cacgccaacc agatcaagca atggaaagac cagctccttg
     1741 agggggcgac aggtgtgttc ggcgatgaaa cgaaagcgga gccgtcgggt ccgaccatcg
     1801 atgtcaaaac gctgcacgcg aaaatcggcg
//
LOCUS       DADXDL010000361         1788 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.253, whole genome shotgun sequence.
ACCESSION   DADXDL010000361 DADXDL010000000
VERSION     DADXDL010000361.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1788)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1788)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1788
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.253"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            <1..503
                     /locus_tag="IRB70_005147"
     CDS             <1..503
                     /locus_tag="IRB70_005147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_031587700.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBC0634909.1"
                     /translation="EEGRETTELYTKLVKWEKDRRFVVSRVLKPEKERAQLSLLEGSE
                     YDYFFFVTNTTLLSEKVVIYYEKRGNAENYIKEAKYDMAVGHLLLKSFWANEAVFQMM
                     MLSYNLFLLFKFDSLDSSEYRQQIKTFRLKYVFLAAKIIKTARYVIMKLSENYPYKGV
                     YEKCLV"
     gene            759..1634
                     /locus_tag="IRB70_005148"
     CDS             759..1634
                     /locus_tag="IRB70_005148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011091028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A extended-spectrum beta-lactamase
                     CTX-M-15"
                     /protein_id="HBC0634910.1"
                     /translation="MVKKSLRQFTLMATATVTLLLGSVPLYAQTADVQQKLAELERQS
                     GGRLGVALINTADNSQILYRADERFAMCSTSKVMAAAAVLKKSESEPNLLNQRVEIKK
                     SDLVNYNPIAEKHVNGTMSLAELSAAALQYSDNVAMNKLIAHVGGPASVTAFARQLGD
                     ETFRLDRTEPTLNTAIPGDPRDTTSPRAMAQTLRNLTLGKALGDSQRAQLVTWMKGNT
                     TGAASIQAGLPASWVVGDKTGSGGYGTTNDIAVIWPKDRAPLILVTYFTQPQPKAESR
                     RDVLASAAKIVTDGL"
     gene            complement(1681..>1788)
                     /locus_tag="IRB70_005149"
     CDS             complement(1681..>1788)
                     /locus_tag="IRB70_005149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000243817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin fold metalloprotein, WbuC family"
                     /protein_id="HBC0634911.1"
                     /translation="ADDYAHWAPAEGEPGTTELMAWYAQAQVGDSTFAV"
BASE COUNT          522 a          375 c          447 g          444 t
ORIGIN      
        1 gagaagaagg tagagaaact acagaactgt atacaaaatt agttaaatgg gaaaaagaca
       61 gaagatttgt cgtatctcgc gtactgaaac cagaaaaaga aagagcacaa ttatcacttt
      121 tagaaggttc cgaatacgac tactttttct ttgtaacaaa tactaccttg ctttctgaaa
      181 aagtagttat atactatgaa aagcgtggta atgctgaaaa ctatatcaaa gaagccaaat
      241 acgacatggc ggtgggtcat ctcttgctaa agtcattttg ggcgaatgaa gccgtgtttc
      301 aaatgatgat gctttcatat aacctatttt tgttgttcaa gtttgattcc ttggactctt
      361 cagaatacag acagcaaata aagacctttc gtttgaagta tgtatttctt gcagcaaaaa
      421 taatcaaaac cgcaagatat gtaatcatga agttgtcgga aaactatccg tacaagggag
      481 tgtatgaaaa atgtctggta taataagaat atcatcaata aaattgagtg ttgctctgtg
      541 gataacttgc agagtttatt aagtatcatt gcagcaaaga tgaaatcaat gatttatcaa
      601 aaatgattga aaggtggttg taaataatgt tacaatgtgt gagaagcagt ctaaattctt
      661 cgtgaaatag tgatttttga agctaataaa aaacacacgt ggaatttagg gactattcat
      721 gttgttgtta tttcgtatct tccagaataa ggaatcccat ggttaaaaaa tcactgcgcc
      781 agttcacgct gatggcgacg gcaaccgtca cgctgttgtt aggaagtgtg ccgctgtatg
      841 cgcaaacggc ggacgtacag caaaaacttg ccgaattaga gcggcagtcg ggaggcagac
      901 tgggtgtggc attgattaac acagcagata attcgcaaat actttatcgt gctgatgagc
      961 gctttgcgat gtgcagcacc agtaaagtga tggccgcggc cgcggtgctg aagaaaagtg
     1021 aaagcgaacc gaatctgtta aatcagcgag ttgagatcaa aaaatctgac cttgttaact
     1081 ataatccgat tgcggaaaag cacgtcaatg ggacgatgtc actggctgag cttagcgcgg
     1141 ccgcgctaca gtacagcgat aacgtggcga tgaataagct gattgctcac gttggcggcc
     1201 cggctagcgt caccgcgttc gcccgacagc tgggagacga aacgttccgt ctcgaccgta
     1261 ccgagccgac gttaaacacc gccattccgg gcgatccgcg tgataccact tcacctcggg
     1321 caatggcgca aactctgcgg aatctgacgc tgggtaaagc attgggcgac agccaacggg
     1381 cgcagctggt gacatggatg aaaggcaata ccaccggtgc agcgagcatt caggctggac
     1441 tgcctgcttc ctgggttgtg ggggataaaa ccggcagcgg tggctatggc accaccaacg
     1501 atatcgcggt gatctggcca aaagatcgtg cgccgctgat tctggtcact tacttcaccc
     1561 agcctcaacc taaggcagaa agccgtcgcg atgtattagc gtcggcggct aaaatcgtca
     1621 ccgacggttt gtaatagcgg aaacggaatg gggaaactca ttccgttttt gtttatcgcc
     1681 ttagacggca aaagtgctgt cgcccacctg cgcttgcgca taccaggcca taagctccgt
     1741 ggttcctggt tctccttccg ctggagccca gtgcgcatag tcatcggc
//
LOCUS       DADXDL010000362         1560 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.266, whole genome shotgun sequence.
ACCESSION   DADXDL010000362 DADXDL010000000
VERSION     DADXDL010000362.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1560)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1560)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1560
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.266"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            19..924
                     /locus_tag="IRB70_005150"
     CDS             19..924
                     /locus_tag="IRB70_005150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000219391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mph(A) family macrolide 2'-phosphotransferase"
                     /protein_id="HBC0634912.1"
                     /translation="MTVVTTADTSQLYALAARHGLKLHGPLTVNELGLDYRIVIATVD
                     DGRRWVLRIPRRAEVSAKVEPEARVLAMLKNRLPFAVPDWRVANAELVAYPMLEDSTA
                     MVIQPGSSTPDWVVPQDSEVFAESFATALAALHAVPISAAVDAGMLIRTPTQARQKVA
                     DDVDRVRREFVVNDKRLHRWQRWLDDDSSWPDFSVVVHGDLYVGHVLIDNTERVSGMI
                     DWSEARVDDPAIDMAAHLMVFGEEGLAKLLLTYEAAGGRVWPRLAHHIAERLAFGAVT
                     YALFALDSGNEEYLAAAKAQLAAAE"
     gene            921..>1560
                     /locus_tag="IRB70_005151"
     CDS             921..>1560
                     /locus_tag="IRB70_005151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000004160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBC0634913.1"
                     /translation="MSERRYSPLATLFAATFLFRIGNAVAALALPWFVLSHTKSAAWA
                     GATAASSVIATIIGAWVGGGLVDRFGRAPVALISGVVGGVAMASIPLLDAVGALSNTG
                     LIACVVLGAAFDAPGMAAQDSELPKLGHVAGLSVERVSSLKAVIGNVAILGGPALGGA
                     AIGLLGAAPTLGLTAFCSVLAGLLGAWVLPARAARTMTTTATLSMRAGVAFLW"
BASE COUNT          226 a          516 c          524 g          294 t
ORIGIN      
        1 agccctcagg agtgaatcat gaccgtagtc acgaccgccg atacctccca actgtacgca
       61 cttgcagccc gacatgggct caagctccat ggcccgctga ctgtcaatga gcttgggctc
      121 gactatagga tcgtgatcgc caccgtcgac gatggacgtc ggtgggtgct gcgcatcccg
      181 cgccgagccg aggtaagcgc gaaggtcgaa ccagaggcgc gggtgctggc aatgctcaag
      241 aatcgcctgc cgttcgcggt gccggactgg cgcgtggcca acgccgagct cgttgcctat
      301 cccatgctcg aagactcgac tgcgatggtc atccagcctg gttcgtccac gcccgactgg
      361 gtcgtgccgc aggactcgga ggtcttcgcg gagagcttcg cgaccgcgct cgccgccctg
      421 catgccgtcc ccatttccgc cgccgtggat gcggggatgc tcatccgtac accgacgcag
      481 gcccgtcaga aggtggccga cgacgttgac cgcgtccgac gcgagttcgt ggtgaacgac
      541 aagcgcctcc accggtggca gcgctggctc gacgacgatt cgtcgtggcc agatttctcc
      601 gtggtggtgc atggcgatct ctacgtgggc catgtgctca tcgacaacac ggagcgcgtc
      661 agcgggatga tcgactggag cgaggcccgc gttgatgacc ctgccatcga catggccgcg
      721 caccttatgg tctttggtga agaggggctc gcgaagctcc tcctcacgta tgaagcggcc
      781 ggtggccggg tgtggccgcg gctcgcccac cacatcgcgg agcgccttgc gttcggggcg
      841 gtcacctacg cactcttcgc cctcgactcg ggtaacgaag agtacctcgc tgcggcgaag
      901 gcgcagctcg ccgcagcgga atgagcgaac gtcgatatag cccgctcgcg acgctgttcg
      961 cggcgacctt tctcttccgg atcggcaacg cggtggcggc cctcgcgctt ccatggttcg
     1021 tcctgtctca tacaaagagc gcggcctggg cgggcgccac ggccgctagc agcgtcatcg
     1081 cgaccatcat cggcgcgtgg gttggtggtg gcctcgtcga tcggttcggg cgcgcgcccg
     1141 tcgcattgat ctcgggtgtg gtgggcggcg tggccatggc gagcatccca ctgctcgatg
     1201 ccgttggcgc cctctcgaac actgggctga tcgcttgcgt ggtgctcggt gccgcgttcg
     1261 acgcacccgg tatggccgcg caggacagtg agctgcccaa actcggccac gtcgccgggc
     1321 tctccgttga gcgcgtctcg tcactgaaag cggtgatcgg gaacgtcgcg attctaggtg
     1381 gcccggccct tgggggggcc gcaatcggcc tgcttggcgc tgcgccaacg ctcgggctga
     1441 cggcgttctg ctccgtcctt gcaggtctgc tcggcgcgtg ggtgcttccc gcgcgtgccg
     1501 ctcggacgat gaccacgacg gcgactctct ccatgcgcgc cggcgtcgct tttctctgga
//
LOCUS       DADXDL010000363         1507 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.268, whole genome shotgun sequence.
ACCESSION   DADXDL010000363 DADXDL010000000
VERSION     DADXDL010000363.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1507)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1507)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1507
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.268"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            37..825
                     /locus_tag="IRB70_005152"
     CDS             37..825
                     /locus_tag="IRB70_005152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000503573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ANT(3'')-Ia family aminoglycoside
                     nucleotidyltransferase AadA5"
                     /protein_id="HBC0634914.1"
                     /translation="MGEFFPAQVFKQLSHARAVIERHLAATLDTIHLFGSAIDGGLKP
                     DSDIDLLVTVSAAPNDSLRQALMLDLLKVSSPPGDGGTWRPLELTVVARSEVVPWRYP
                     ARRELQFGEWLRHDILSGTFEPAVLDHDLAILLTKARQHSLALLGPSAATFFEPVPKE
                     HFSKALFDTIAQWNAESDWKGDERNVVLALARIWYSASTGLIAPKDVAAAWVSERLPA
                     EHRPLICKARAAYLGSEDDDLAMRVEETAAFVRYAKATIERILR"
     gene            1031..1378
                     /locus_tag="IRB70_005153"
     CDS             1031..1378
                     /locus_tag="IRB70_005153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000679427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="quaternary ammonium compound efflux SMR
                     transporter QacE delta 1"
                     /protein_id="HBC0634915.1"
                     /translation="MKGWLFLVIAIVGEVIATSALKSSEGFTKLAPSAVVIIGYGIAF
                     YFLSLVLKSIPVGVAYAVWSGLGVVIITAIAWLLHGQKLDAWGFVGMGLIIAAFLLAR
                     SPSWKSLRRPTPW"
     gene            1372..>1507
                     /locus_tag="IRB70_005154"
     CDS             1372..>1507
                     /locus_tag="IRB70_005154"
                     /EC_number="2.5.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001747810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydropteroate synthase"
                     /protein_id="HBC0634916.1"
                     /translation="MVTVFGILNLTEDSFFDESRRLDPAGAVTAAIEMLRVGSDVVDV
                     G"
BASE COUNT          304 a          411 c          423 g          369 t
ORIGIN      
        1 acttaaaagc tgccgctgaa cttaacgtta ggcatcatgg gtgaattttt ccctgcacaa
       61 gttttcaagc agctgtccca cgctcgcgcg gtgatcgagc gccatctggc tgcgacactg
      121 gacacaatcc acctgttcgg atctgcgatc gatggagggc tgaagccgga cagcgacata
      181 gacttgctcg tgaccgtcag cgccgcacct aacgattcgc tccggcaggc gctaatgctc
      241 gatttgctga aagtctcatc accgccaggc gatggcggaa catggcgacc gctggagcta
      301 actgttgtcg ctcgaagcga agtagtgcct tggcgctatc cggcgcggcg tgagcttcag
      361 ttcggtgagt ggctccgcca cgacatcctt tccggaacgt tcgagcctgc cgttctggat
      421 cacgatcttg cgattttgct gaccaaggcg aggcaacaca gccttgcgct tctaggccca
      481 tccgcagcca cgtttttcga gccggtgccg aaggagcatt tctccaaggc gcttttcgac
      541 actattgccc agtggaatgc agagtcggat tggaagggtg acgagcggaa cgtcgttctt
      601 gctcttgctc gcatttggta cagcgcttca actggtctca ttgctcctaa ggacgttgct
      661 gccgcatggg tatcggagcg tttgcctgcc gagcatcggc ccctcatctg caaggcacgc
      721 gcggcgtacc tgggtagcga ggacgacgac ctagcaatgc gcgtcgaaga gacggccgcg
      781 ttcgttcgat atgccaaagc aacgattgag agaatcttgc gttgagcggc atgtgcgaaa
      841 agtgcatcga cccgcgccga gggcatctga tgcctaactc ggcgttcaag cggacgggct
      901 gcgcccgccg ctcaactatg cgttagatgc actaagcaca taattgctca cagccaaact
      961 atcaggtcaa gtctgctttt attattttta agcgtgcata ataagcccta cacaaattgg
     1021 gagatatatc atgaaaggct ggctttttct tgttatcgca atagttggcg aagtaatcgc
     1081 aacatccgca ttaaaatcta gcgagggctt tactaagctt gccccttccg ccgttgtcat
     1141 aatcggttat ggcatcgcat tttattttct ttctctggtt ctgaaatcca tccctgtcgg
     1201 tgttgcttat gcagtctggt cgggactcgg cgtcgtcata attacagcca ttgcctggtt
     1261 gcttcatggg caaaagcttg atgcgtgggg ctttgtaggt atggggctca taattgctgc
     1321 ctttttgctc gcccgatccc catcgtggaa gtcgctgcgg aggccgacgc catggtgacg
     1381 gtgttcggca ttctgaatct caccgaggac tccttcttcg atgagagccg gcggctagac
     1441 cccgccggcg ctgtcaccgc ggcgatcgaa atgctgcgag tcggatcaga cgtcgtggat
     1501 gtcggac
//
LOCUS       DADXDL010000364         1240 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.284, whole genome shotgun sequence.
ACCESSION   DADXDL010000364 DADXDL010000000
VERSION     DADXDL010000364.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 1240)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1240)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1240
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.284"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            90..950
                     /locus_tag="IRB70_005155"
     CDS             90..950
                     /locus_tag="IRB70_005155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032489893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A broad-spectrum beta-lactamase TEM-1"
                     /protein_id="HBC0634917.1"
                     /translation="MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDQLGARVGY
                     IELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVE
                     YSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRL
                     DRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPL
                     LRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIA
                     EIGASLIKHW"
     gene            complement(1130..1240)
                     /locus_tag="IRB70_005156"
                     /pseudo
     CDS             complement(1130..1240)
                     /locus_tag="IRB70_005156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010349194.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
BASE COUNT          341 a          280 c          294 g          325 t
ORIGIN      
        1 atgataagtt tatcaccacc gactatttgc aacagtgcct gagacaataa ccctggtaaa
       61 tgcttcaata atattgaaaa aggaagagta tgagtattca acattttcgt gtcgccctta
      121 ttcccttttt tgcggcattt tgccttcctg tttttgctca cccagaaacg ctggtgaaag
      181 taaaagatgc tgaagatcag ttgggtgcac gagtgggtta catcgaactg gatctcaaca
      241 gcggtaagat ccttgagagt tttcgccccg aagaacgttt tccaatgatg agcactttta
      301 aagttctgct atgtggtgcg gtattatccc gtgttgacgc cgggcaagag caactcggtc
      361 gccgcataca ctattctcag aatgacttgg ttgagtactc accagtcaca gaaaagcatc
      421 ttacggatgg catgacagta agagaattat gcagtgctgc cataaccatg agtgataaca
      481 ctgctgccaa cttacttctg acaacgatcg gaggaccgaa ggagctaacc gcttttttgc
      541 acaacatggg ggatcatgta actcgccttg atcgttggga accggagctg aatgaagcca
      601 taccaaacga cgagcgtgac accacgatgc ctgcagcaat ggcaacaacg ttgcgcaaac
      661 tattaactgg cgaactactt actctagctt cccggcaaca attaatagac tggatggagg
      721 cggataaagt tgcaggacca cttctgcgct cggcccttcc ggctggctgg tttattgctg
      781 ataaatctgg agccggtgag cgtgggtctc gcggtatcat tgcagcactg gggccagatg
      841 gtaagccctc ccgtatcgta gttatctaca cgacggggag tcaggcaact atggatgaac
      901 gaaatagaca gatcgctgag ataggtgcct cactgattaa gcattggtaa ctgtcagacc
      961 aagtttactc atatatactt tagattgatt taaaacttca tttttaattt aaaaggatct
     1021 aggtgaagat cctttttgat aatctcatga ccaaaatccc ttaacgtgag ttttcgttcc
     1081 actgagcgtc agaccccttg atcgaggtgg ccagccgcag gatttcgtta ataaataaat
     1141 ttgccgcatg gagtaagccg ctatcaatgt cgggcgacaa taacggatgc tgaagacaac
     1201 tgctacattt accacaacgt tcggcacttg gctcatcgag
//
LOCUS       DADXDL010000365          900 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.307, whole genome shotgun sequence.
ACCESSION   DADXDL010000365 DADXDL010000000
VERSION     DADXDL010000365.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..900
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.307"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            complement(<1..193)
                     /locus_tag="IRB70_005157"
     CDS             complement(<1..193)
                     /locus_tag="IRB70_005157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_005221021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage integrase N-terminal SAM-like
                     domain-containing protein"
                     /protein_id="HBC0634918.1"
                     /translation="MKTATAPLPPLRSVKVLDQLRERIRYLHYSLRTEQAYVHWVRAF
                     IRFHGVRHPATLGSSEVEAF"
     gene            351..824
                     /locus_tag="IRB70_005158"
     CDS             351..824
                     /locus_tag="IRB70_005158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001389366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrA17"
                     /protein_id="HBC0634919.1"
                     /translation="MKISLISAVSENGVIGSGPDIPWSVKGEQLLFKALTYNQWLLVG
                     RKTFDSMGVLPNRKYAVVSKNGISSSNENVLVFPSIENALKELSKVTDHVYVSGGGQI
                     YNSLIEKADIIHLSTVHVEVEGDIKFPIMPENFNLVFEQFFMSNINYTYQIWKKG"
BASE COUNT          255 a          180 c          211 g          254 t
ORIGIN      
        1 gaaatgcctc gacttcgctg ctgcccaagg ttgccgggtg acgcacaccg tggaaacgga
       61 tgaaggcacg aacccagtgg acataagcct gttcggttcg taaactgtaa tgcaagtagc
      121 gtatgcgctc acgcaactgg tccagaacct tgaccgaacg cagcggtggt aacggcgcag
      181 tggcggtttt catggcttgt tatgactgtt tttttgtaca gtctatgcct cgggcatcca
      241 agcagcaagc gcgttacgcc gtgggtcgat gtttgatgtt atggagcagc aacgatgtta
      301 cgcagcaggg cagtcgccct aaaacaaagt tagccattaa gggagttaaa ttgaaaatat
      361 cattgatttc tgcagtgtca gaaaatggcg taatcggtag tggtcctgat atcccgtggt
      421 cagtaaaagg tgagcaacta ctctttaaag cgctcacata taatcaatgg ctccttgtcg
      481 gaagaaaaac atttgactct atgggtgttc ttccaaatcg caaatatgca gtagtgtcaa
      541 agaacggaat ttcaagctca aatgaaaacg tcctagtttt tccttcaata gaaaatgctt
      601 tgaaagagct atcaaaagtt acagatcatg tatatgtctc tggcgggggt caaatctata
      661 atagccttat tgaaaaagca gatataattc atttgtctac tgttcacgtt gaagtcgaag
      721 gtgatatcaa attccctata atgcctgaga atttcaattt ggtttttgaa cagtttttta
      781 tgtctaatat aaattataca taccagattt ggaaaaaagg ctaacaatgc gttgcagcac
      841 cagtcgcttc gctccttgga cagcttttaa gtcgcgtctt tgtggttttg ctgcgcaaaa
//
LOCUS       DADXDL010000366          685 bp    DNA     linear   BCT 16-APR-2021
DEFINITION  TPA_asm: Escherichia coli strain Escherichia coli ARLG-4248
            SAMN15868262-rid10733343.guided.327, whole genome shotgun sequence.
ACCESSION   DADXDL010000366 DADXDL010000000
VERSION     DADXDL010000366.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN15868262
            Sequence Read Archive: SRR12508843
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Escherichia coli
  ORGANISM  Escherichia coli
            Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
            Enterobacteriaceae; Escherichia.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (08-OCT-2020) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 08-OCT-2020
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT000858000.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT000858000.1
            Genome Coverage       :: 96x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 04/16/2021 10:45:54
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 5,159
            CDSs (total)                      :: 5,084
            Genes (coding)                    :: 4,956
            CDSs (with protein)               :: 4,956
            Genes (RNA)                       :: 75
            rRNAs                             :: 2, 2, 4 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 2, 4 (16S, 23S)
            tRNAs                             :: 62
            ncRNAs                            :: 5
            Pseudo Genes (total)              :: 128
            CDSs (without protein)            :: 128
            Pseudo Genes (ambiguous residues) :: 0 of 128
            Pseudo Genes (frameshifted)       :: 49 of 128
            Pseudo Genes (incomplete)         :: 72 of 128
            Pseudo Genes (internal stop)      :: 32 of 128
            Pseudo Genes (multiple problems)  :: 23 of 128
            CRISPR Arrays                     :: 2
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Escherichia coli"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN15868262-rid10733343.guided.327"
                     /strain="Escherichia coli ARLG-4248"
                     /isolation_source="urine"
                     /host="Homo sapiens"
                     /db_xref="taxon:562"
                     /country="USA: Northeast"
                     /collection_date="2017"
                     /collected_by="MDRO network"
     gene            259..>685
                     /gene="gpt"
                     /locus_tag="IRB70_005159"
     CDS             259..>685
                     /gene="gpt"
                     /locus_tag="IRB70_005159"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_308292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBC0634920.1"
                     /translation="MSEKYIVTWDMLQIHARKLASRLMPSEQWKGIIAVSRGGLVPGA
                     LLARELGIRHVDTVCISSYDHDNQRELKVLKRAEGDGEGFIVIDDLVDTGGTAVAIRE
                     MYPKAHFVTIFAKPAGRPLVDDYVVDIPQDTWIEQPWDMG"
BASE COUNT          177 a          160 c          178 g          170 t
ORIGIN      
        1 taagtctcct tgtcgatcac ccgcaaaaca gtattgcagg tcacagggtt agcagaaaat
       61 gttgtcaaca caagacaggc ttgcgagata tgtttgagaa taccacttta tcccgcgtca
      121 gggagaggca gtgcgtaaaa agacgcggac tcatgtgaaa tactggtttt tagtgcgcca
      181 gatctctata atctcgcgca acctattttc ccctcgaaca ctttttaagc cgtagataaa
      241 caggctggga cacttcacat gagcgaaaaa tacatcgtca cctgggacat gttgcagatc
      301 catgcacgta aactcgcaag ccgactgatg ccttctgaac aatggaaagg cattattgcc
      361 gtaagccgtg gcggtctggt accgggtgcg ttactggcgc gtgaactggg tattcgtcat
      421 gtcgataccg tttgtatttc cagctacgat cacgacaacc agcgcgagct taaagtgctg
      481 aaacgcgcag aaggcgatgg cgaaggcttc atcgttattg atgacctggt agataccggt
      541 ggtactgcgg ttgcgattcg tgaaatgtat ccaaaagcgc actttgtcac catcttcgca
      601 aaaccggctg gtcgtccgct ggttgatgac tatgttgttg atatcccgca agatacctgg
      661 attgaacagc cgtgggatat gggcg
//
